model_p beta_cntot stde_cntot t_val_cntot pval_cntot beta_loh stde_loh tval_loh pval_loh gene class fdr_model fdr_loh fdr_cntot ass_coeff_CN ass_coeff_LOH 4.55530030531295e-17 241.582467094759 30.4321685494473 7.93839146566985 5.57633216094125e-14 -265.038440593182 101.767339807259 -2.60435657545092 0.00971642775001486 DPM1 other 6.33961143490403e-13 1 8.0299183117554e-10 7.93839146566985 -2.60435657545092 7.596354327003e-14 116.977254759934 14.7339418097898 7.93930478822785 5.36986034095552e-14 -83.7597235299213 50.4208346207769 -1.6612125554821 0.0978229126194425 SCYL3 other 9.72029499683304e-10 1 7.73420984907823e-10 7.93930478822785 -1.6612125554821 1.43951921024184e-12 146.938299970221 19.2818081768903 7.62056642313918 4.21547524535376e-13 -69.4645179905161 65.9840301955423 -1.05274742668278 0.293391076712799 C1orf112 other 1.76384288830933e-08 1 5.99187651374583e-09 7.62056642313918 -1.05274742668278 0.66806104138503 -27.3833314147576 68.2621005128964 -0.401149850488181 0.688625916990106 -88.9583063994829 99.8929077596882 -0.890536759761657 0.37396765065382 FGR other 1 1 1 -0.401149850488181 -0.890536759761657 0.0378541658417756 -302.250796128459 153.714197342594 -1.96631671864903 0.0502978668213391 -782.258397373207 418.631760013741 -1.86860738264945 0.0627724455009361 CFH other 1 1 1 -1.96631671864903 -1.86860738264945 0.0345283623736139 107.36340952459 84.4732876119664 1.27097467802805 0.20481956533939 -256.166788262994 149.04929184708 -1.71867162257848 0.0868078425724061 FUCA2 other 1 1 1 1.27097467802805 -1.71867162257848 1.1796763244663e-06 2828.66196444491 611.709858089795 4.62418894682859 5.88369580698646e-06 -1357.16424796499 1426.33908507752 -0.951501828817394 0.342216708989712 GCLC other 0.0104495728821225 1 0.0615199233578504 4.62418894682859 -0.951501828817394 2.40629933503403e-10 199.148674651298 35.6857857318578 5.58061621923354 5.77367663739154e-08 -131.340261838869 74.6773292941598 -1.7587702061694 0.0797368920625271 NFYA other 2.68807698716652e-06 1 0.000691397777327637 5.58061621923354 -1.7587702061694 0.0412603735551784 40.5889386803236 26.630438656609 1.52415584300751 0.128631598480921 -29.9698551330544 39.7899481150213 -0.753201664058976 0.451980168328883 STPG1 other 1 1 1 1.52415584300751 -0.753201664058976 0.000769937082743005 58.5228862773784 49.4715132549006 1.18296131302555 0.237857429254515 -167.392426548562 73.9180067954143 -2.26456899753615 0.0243263724459131 NIPAL3 other 1 1 1 1.18296131302555 -2.26456899753615 0.491346292559716 33.4881215733052 35.8978932398656 0.932871501665611 0.35171670070963 -36.8948451255147 91.5274723212549 -0.403101322365993 0.687191521838304 ENPP4 other 1 1 1 0.932871501665611 -0.403101322365993 0.0403606501258964 428.110052963944 218.640052345626 1.95805868307783 0.051249015377558 -462.201714052907 517.49191583183 -0.893157361327959 0.372565353786214 SEMA3F other 1 1 1 1.95805868307783 -0.893157361327959 0.641390799772535 -33.1407497293503 57.8684558966685 -0.57269110115064 0.567335800135633 -148.869172109402 166.094904109506 -0.896289822421364 0.370905369974469 CFTR other 1 1 1 -0.57269110115064 -0.896289822421364 4.20564370957532e-76 549.405991670239 20.723859562763 26.5107949610612 7.08505480968786e-77 -55.2355573499372 190.116802040065 -0.290534854138231 0.771631783960272 ANKIB1 other 6.71346905359509e-72 1 1.13105814981857e-72 26.5107949610612 -0.290534854138231 5.39807180918134e-76 1027.7857393922 38.76018638344 26.516532434202 5.12108422844275e-77 206.282318519491 355.603155400492 0.580091361358055 0.562338580441755 CYP51A1 other 8.61586241463434e-72 1 8.17581097070886e-73 26.516532434202 0.580091361358055 7.80695230443848e-92 473.520460524576 14.953451315457 31.666299005843 9.93747861970996e-93 21.2863545011803 137.189600155689 0.155160117654862 0.876811449443872 KRIT1 other 1.24700449158796e-87 1 1.58731345992627e-88 31.666299005843 0.155160117654862 9.0733934500929e-18 68.4293257888081 7.27554328983793 9.40539050662874 2.62517829223565e-18 6.36516745067067 32.7382814004945 0.194425827452706 0.845991996752623 RAD52 other 1.28016508187361e-13 1 3.97583252359089e-14 9.40539050662874 0.194425827452706 0.000272384114114345 137.048302105123 50.1974249975818 2.73018590319572 0.0067416426692272 -225.256281988517 110.626568189161 -2.03618611402054 0.0426968125797377 BAD other 1 1 1 2.73018590319572 -2.03618611402054 0.000250865166167958 -17.533736192589 176.69407966744 -0.0992321657046442 0.921027571083704 -804.116033493124 254.393495037424 -3.16091428900267 0.00175191317702073 LAP3 other 1 1 1 -0.0992321657046442 -3.16091428900267 0.000127358767438292 -65.9454298898346 118.203505171834 -0.557897414243077 0.577375012757602 -614.425140214866 171.32029831717 -3.58641180438155 0.000397616157080571 HS3ST1 other 0.931374666276233 1 1 -0.557897414243077 -3.58641180438155 0.89973411351564 12.0034983533469 27.9199653194652 0.429925260149885 0.667589165675489 2.24683327883355 70.4058492424109 0.03191259395363 0.974565073727691 AOC1 other 1 1 1 0.429925260149885 0.03191259395363 0.44582598097878 -52.0147489964367 58.66219886835 -0.886682565601887 0.376041846095413 -188.78868261932 160.442430798621 -1.17667553202481 0.240365209021323 WNT16 other 1 1 1 -0.886682565601887 -1.17667553202481 0.00159374592636057 28.4326085730025 8.40949632874875 3.38101206796448 0.000828554179882703 -4.96243918385235 24.5063321013878 -0.20249620234157 0.839680765929079 HECW1 other 1 1 1 3.38101206796448 -0.20249620234157 7.06687872279295e-09 204.98273585392 33.234408254548 6.16778653869574 2.51882338697767e-09 0.939219911311307 81.5196704246931 0.0115213899469693 0.990815972616941 MAD1L1 other 7.26545801490343e-05 1 3.20595840694517e-05 6.16778653869574 0.0115213899469693 2.8425374284211e-06 439.233237399454 183.270727025209 2.39663608329025 0.0172423214435186 -995.949985978894 350.71273490033 -2.83978848461815 0.00486571038353978 LASP1 other 0.024354860686712 1 1 2.39663608329025 -2.83978848461815 4.54346189735303e-05 81.630336749963 26.6377393679107 3.06446187578138 0.00240051970790389 -120.472044714163 56.3056682892152 -2.13960775841174 0.0332797774006767 SNX11 other 0.349277937971252 1 1 3.06446187578138 -2.13960775841174 0.172396873057274 -156.699164328752 92.4562961758727 -1.69484578995761 0.0912449586069372 -338.192772002652 233.147282798805 -1.45055420737842 0.148052009268796 TMEM176A other 1 1 1 -1.69484578995761 -1.45055420737842 8.52652597414728e-30 1053.62903513326 82.3065173994462 12.8012831598722 1.15781171810772e-29 -247.196242010301 384.801993469186 -0.642398548359121 0.521157517231834 M6PR other 1.33465711073327e-25 1 1.82471126773776e-25 12.8012831598722 -0.642398548359121 0.00633842358680192 59.3198410069559 23.098955825003 2.56807456823422 0.0107609062273218 211.096711304595 102.374466598493 2.06200548162564 0.0401570116917578 CYP26B1 other 1 1 1 2.56807456823422 2.06200548162564 0.0239164469307048 -42.8912540315541 42.7336621471351 -1.00368776923158 0.316424472480194 -305.990610672344 112.701363048133 -2.71505687594622 0.0070519788496454 ICA1 other 1 1 1 -1.00368776923158 -2.71505687594622 2.83913857674401e-06 118.008823813723 46.8575798475986 2.51845750885 0.0123855991418732 -174.493913048733 76.3534835733203 -2.28534318124687 0.0230950228965418 DBNDD1 other 0.0243285784641194 1 1 2.51845750885 -2.28534318124687 3.64672557366916e-23 299.354045901089 27.9322795530681 10.7171362556483 1.49926157841491e-22 2.63958110870435 63.8242052376972 0.041357054096857 0.967041928627746 ALS2 other 5.51348439483041e-19 1 2.32130670185981e-18 10.7171362556483 0.041357054096857 0.158344452960024 36.9485164071384 33.0237579493498 1.11884651237476 0.264226471862301 -78.9985610807973 73.5816066034223 -1.07361832294 0.283977842604377 CASP10 other 1 1 1 1.11884651237476 -1.07361832294 0.181243881084298 26.0133837803066 197.921413103096 0.131432892340741 0.895533356017755 -742.905497404043 440.996920449879 -1.68460472840984 0.0932511237109152 CFLAR other 1 1 1 0.131432892340741 -1.68460472840984 0.42923479513386 -238.708482435895 213.678840207979 -1.11713673756163 0.264936366928194 -519.167006161729 536.270948765475 -0.968105781894172 0.333864384838483 TFPI other 1 1 1 -1.11713673756163 -0.968105781894172 3.471816445192e-13 87.4345644101243 10.9638354395602 7.97481546417953 4.2550442388191e-14 42.1854554776962 40.5304426839223 1.04083381981985 0.298876950705481 NDUFAF7 other 4.34845009760298e-09 1 6.13960333219208e-10 7.97481546417953 1.04083381981985 2.28790475130262e-05 212.18249643512 104.665603411618 2.02724189723219 0.0436163972172065 -829.553043971718 247.729558468778 -3.34862359219144 0.000927330798332526 RBM5 other 0.181591000110889 1 1 2.02724189723219 -3.34862359219144 1.81138653536986e-05 51.4170971475123 15.1067851856915 3.40357637415883 0.000765637748439922 -15.3147466897692 25.4089072262495 -0.602731418293654 0.547191411322613 MTMR7 other 0.145182630809895 1 1 3.40357637415883 -0.602731418293654 0.201122360035078 95.7208576859427 122.810122059189 0.779421566243613 0.436411545146592 -168.934732854039 206.560890321119 -0.817844716835865 0.414164344634117 SLC7A2 other 1 1 1 0.779421566243613 -0.817844716835865 6.12711206691834e-16 977.519617659678 146.24727686259 6.68401927632559 1.30483520672955e-10 -1092.18477117639 392.075188732317 -2.78565133057185 0.00571624434933284 ARF5 other 8.29672244981412e-12 1 1.73869291296712e-06 6.68401927632559 -2.78565133057185 4.24287403144684e-12 253.93455538074 37.3272934371033 6.80291904390608 7.21784834077935e-11 -16.4504751511887 86.7259766259397 -0.189683365828691 0.849707566726583 SARM1 other 5.10035887320224e-08 1 9.68635247332589e-07 6.80291904390608 -0.189683365828691 1.20348776517474e-32 863.006588469076 76.2417135114983 11.3193493262572 2.36783343010964e-24 -483.133771234237 177.139472355832 -2.72742017806022 0.00682476671380799 POLDIP2 other 1.89525253259717e-28 1 3.69263623425598e-20 11.3193493262572 -2.72742017806022 0.000861921395742509 251.283692296071 83.250303930621 3.01841171061051 0.00278300788485575 -684.018196389282 386.417120207788 -1.77015499732896 0.0778256432267519 PLXND1 other 1 1 1 3.01841171061051 -1.77015499732896 4.64321458822336e-16 495.773898287649 136.044940009925 3.64419211954139 0.000321638420468678 -956.071502031166 193.576373850625 -4.93898859149479 1.37813364766594e-06 AK2 other 6.30687837518379e-12 0.0215168006410084 1 3.64419211954139 -4.93898859149479 0.0784094821127922 -16.6754033198859 60.9337423669149 -0.273664519396729 0.784552453720762 -166.693833225159 89.2642238047549 -1.86742040786423 0.0629303801195655 CD38 other 1 1 1 -0.273664519396729 -1.86742040786423 2.33522835761713e-17 2123.22065155596 229.53496801499 9.25009670603785 6.9620501953586e-18 -0.876230583867956 1084.37670021223 -0.000808049991941421 0.999355863951763 FKBP4 other 3.27118788335008e-13 1 1.05043413347571e-13 9.25009670603785 -0.000808049991941421 9.15599985936981e-13 754.133188445947 187.715206491638 4.0174325913204 7.61964771517108e-05 -857.094053244162 277.604621846828 -3.08746319690987 0.00222737527538073 KDM1A other 1.13012506264202e-08 1 0.724018925895556 4.0174325913204 -3.08746319690987 0.00149735366037181 212.686351467851 131.714067718177 1.61475805244226 0.107531060317183 -779.970862259334 307.099355589026 -2.53979973602786 0.0116526859952315 RBM6 other 1 1 1 1.61475805244226 -2.53979973602786 1.44363204856275e-08 137.844556451613 26.5206042031743 5.19764012145373 3.95919782960948e-07 -145.663849929873 79.8749105154011 -1.82364961650614 0.0692983803940012 CAMKK1 other 0.000145518110495125 1 0.00451150592684001 5.19764012145373 -1.82364961650614 3.38107667904808e-16 300.017030672845 33.6639405247794 8.91211860512908 8.69788932687646e-17 59.7408963691661 152.463776698855 0.391836655648153 0.695497431018937 RECQL other 4.60806940587462e-12 1 1.29981258100842e-12 8.91211860512908 0.391836655648153 1.64225625949459e-25 151.285603469135 12.929320094775 11.7009713086361 9.3341541642304e-26 -37.0999416433792 60.577540226016 -0.612437241673377 0.540775656856317 VPS50 other 2.52332674271344e-21 1 1.46126183441027e-21 11.7009713086361 -0.612437241673377 0.19148609180487 29.2076619516512 29.237486442751 0.998979922875443 0.318702183542856 201.445796405406 116.974156504266 1.72213933765839 0.0861937371763496 HSPB6 other 1 1 1 0.998979922875443 1.72213933765839 4.44613049302353e-07 93.6492884420801 17.3495310946949 5.39779939474651 1.48601464249807e-07 -1.75680238802442 69.311033458398 -0.0253466482948763 0.979797328511624 ARHGAP33 other 0.00407710166210258 1 0.00173893433465124 5.39779939474651 -0.0253466482948763 4.71497697926349e-18 425.798743224723 54.2561394194274 7.84793661659345 9.74424012907244e-14 -155.750992423763 113.601853891723 -1.37102509411698 0.171497276445888 NDUFAB1 essential 6.68630885429355e-14 1 1.39849334332448e-09 7.84793661659345 -1.37102509411698 0.422126622479228 -100.891347444663 92.1347139449081 -1.09504163115968 0.274492650481779 -353.031534555067 383.745832094547 -0.919961873274724 0.358429343492996 PDK4 other 1 1 1 -1.09504163115968 -0.919961873274724 0.445964566480791 0.0079066357834664 1.70738397458689 0.00463084807000103 0.996308538047396 -3.75662619112152 3.19977446015987 -1.17402843165822 0.241414331347191 SLC22A16 other 1 1 1 0.00463084807000103 -1.17402843165822 0.973118717663847 7.82402220411494 42.1421790018659 0.18565775167365 0.852852044855704 -7.20736693536669 99.7449310638155 -0.0722579770069269 0.942449906143503 ZMYND10 other 1 1 1 0.18565775167365 -0.0722579770069269 1.48136404999139e-09 185.381847256313 29.1284131970644 6.36429612564671 8.63184867755574e-10 -75.4293334730188 120.43166637677 -0.626324751141766 0.531643121438124 SLC25A13 other 1.58639276113578e-05 1 1.11773808525669e-05 6.36429612564671 -0.626324751141766 1.0365420436848e-12 270.608154289012 42.003676663561 6.44248731977716 5.39688868817881e-10 -177.165361141372 89.5014301076867 -1.9794696121415 0.0487825068475232 CDC27 essential 1.2766051810022e-08 1 7.0386222271228e-06 6.44248731977716 -1.9794696121415 1.43594887373678e-32 670.014115518202 48.0888006070836 13.9328514552203 1.14130411027698e-33 473.319315059312 143.878692434904 3.28971098533898 0.00113515216448784 DVL2 other 2.26118869147331e-28 1 1.80736918903462e-29 13.9328514552203 3.28971098533898 0.018058649591882 5.52035025271791 116.795273316239 0.0472651854477948 0.962336687493854 -502.181887713829 211.476438393691 -2.37464698917878 0.0182622874897949 PRSS22 other 1 1 1 0.0472651854477948 -2.37464698917878 1.42242144281928e-17 861.305018683159 133.565063200641 6.44858017541093 5.13286773750916e-10 -1022.92211055276 308.93054627984 -3.31117179207706 0.00105470566703522 UPF1 essential 2.00035127503676e-13 1 6.69941897099696e-06 6.44858017541093 -3.31117179207706 5.20547879662057e-05 85.1326372935069 40.7491427618973 2.08918842270986 0.0376235287069259 -361.607455801484 113.582943889715 -3.18364222142886 0.00162399031735825 SKAP2 other 0.398167073153508 1 1 2.08918842270986 -3.18364222142886 4.26051995348994e-07 133.918009740946 41.407290494673 3.23416500188956 0.00137234746851177 -113.172318140751 65.1512440014239 -1.73707071714974 0.0835193450529824 MCUB other 0.00391286152528516 1 1 3.23416500188956 -1.73707071714974 0.000910055124295909 27.8357106824466 7.34620001477263 3.78913052006087 0.000186302592951438 21.5453589550587 20.3042466125604 1.06112575197597 0.28957750759254 HOXA11 og 1 1 1 3.78913052006087 1.06112575197597 5.63096090428251e-25 287.666282207862 26.7355457799487 10.7596936518726 1.0858774115778e-22 -197.107352727424 108.941366573753 -1.80929759673965 0.071521000246921 POLR2J essential 8.62269043272781e-21 1 1.68224128601633e-18 10.7596936518726 -1.80929759673965 1.2003995601721e-23 401.945305771334 36.0492157198328 11.1499043112386 5.0080492899479e-24 109.799941404605 105.375461530639 1.04198776270773 0.298342601363399 DHX33 essential 1.82172637251718e-19 1 7.80203998880983e-20 11.1499043112386 1.04198776270773 0.270729381885168 -13.6529346132389 9.73108223526514 -1.40302324892098 0.161754562765053 -26.2439771976735 19.9814264996235 -1.31341859892576 0.190152844261325 MEOX1 other 1 1 1 -1.40302324892098 -1.31341859892576 0.425695688858915 22.7037108240378 26.3768782686891 0.860742904932327 0.390140534416559 -52.2849782466051 67.0905523627697 -0.77931953762866 0.436471527513768 THSD7A other 1 1 1 0.860742904932327 -0.77931953762866 1.48323838839081e-19 388.191759711967 60.1746209782082 6.4510877410021 5.11172497787852e-10 -441.011564702094 117.529899522127 -3.75233507809702 0.00021446672027722 LIG3 other 2.154997054493e-15 1 6.67233461362483e-06 6.4510877410021 -3.75233507809702 5.98105137586975e-13 181.684444729798 27.8030255111759 6.53470050073388 3.17967630992111e-10 -156.384239275378 71.2179295091293 -2.19585489712014 0.0289562614095078 RPAP3 essential 7.43384875506851e-09 1 4.17936654176031e-06 6.53470050073388 -2.19585489712014 9.4566400192601e-05 108.627699897719 30.6097154661088 3.5487980937945 0.000456273936702045 -29.3365050237659 61.4479824223715 -0.47742015062622 0.633449203002321 ACSM3 other 0.703101185431988 1 1 3.5487980937945 -0.47742015062622 2.06700460572954e-23 367.371493765297 51.7367307276502 7.10078678336276 1.07566817952158e-11 -259.966523343067 90.8166666703347 -2.8625420076994 0.00452821116668264 CIAPIN1 essential 3.13130527721969e-19 1 1.47839834593446e-07 7.10078678336276 -2.8625420076994 2.81255760335683e-06 137.215880199454 71.7928357123763 1.91127539172825 0.0570240157434057 -350.516622814366 120.80917586573 -2.90140728386341 0.00401986476725108 SPPL2B other 0.0241064312183714 1 1 1.91127539172825 -2.90140728386341 1.22700808264091e-11 67.3533717359745 22.1400285076244 3.0421537945527 0.00258558981590148 -260.752100640307 59.0224168756992 -4.41784858097983 1.45608448740328e-05 FAM214B other 1.45093705772288e-07 0.223232312763796 1 3.0421537945527 -4.41784858097983 0.0589425995009054 16.3640847008276 41.8114607311074 0.391377971845238 0.695825420598371 -184.664092409814 88.3792053859237 -2.08945182979916 0.0375996315357527 COPZ2 other 1 1 1 0.391377971845238 -2.08945182979916 0.33388158290159 23.6926312564084 20.7171846209872 1.14362215184427 0.253785860534803 -44.3724946675882 73.4493536515552 -0.604123691517994 0.546264948497933 PRKAR2B other 1 1 1 1.14362215184427 -0.604123691517994 2.86337268403805e-13 668.533716535468 127.238373093729 5.25418315466041 2.99895004726706e-07 -558.997083893638 233.391543283661 -2.39510427853952 0.0172898026697706 CREBBP og 3.59754144022541e-09 1 0.00344429412928622 5.25418315466041 -2.39510427853952 0.206360265129594 48.4715291203479 29.1082897391014 1.66521391516986 0.0970172102782637 -9.31840168048477 61.9898146245354 -0.150321496151024 0.880621976794993 TSPOAP1 other 1 1 1 1.66521391516986 -0.150321496151024 5.20550595768818e-07 100.8400907164 18.5000523021771 5.45080030419875 1.1342469370729e-07 103.306674576543 78.2069162084768 1.32094039229418 0.187643823887883 GCFC2 other 0.00474638033222009 1 0.00133773083758377 5.45080030419875 1.32094039229418 5.6434877735133e-05 133.971198455126 29.9144360560372 4.47847982840674 1.11052996428386e-05 -33.0892945455033 128.886287834283 -0.256732466281039 0.797580827973746 WDR54 other 0.430090203219449 1 0.113618320645882 4.47847982840674 -0.256732466281039 0.0620634323005433 15.1507781330094 37.6806779756842 0.402083480100499 0.687952929554815 -273.445068301319 129.73863220573 -2.10766110026279 0.036017779511285 CROT other 1 1 1 0.402083480100499 -2.10766110026279 0.676964456806578 -0.604200361245233 2.06051461283354 -0.293227894372639 0.769580084709998 -6.22434981760659 7.04753600363645 -0.883195178342458 0.377940487269478 ABCB4 other 1 1 1 -0.293227894372639 -0.883195178342458 9.67836260508358e-09 254.84633619341 48.0249618512711 5.3065390657185 2.34375961042251e-07 -331.946446253005 184.125354697134 -1.80282855014195 0.072538426988096 KMT2E other 9.87483336596678e-05 1 0.00271079236541467 5.3065390657185 -1.80282855014195 6.99414770698804e-05 389.115242347726 106.66835610693 3.64789761977447 0.000317045453128123 -451.852226995812 345.651864988611 -1.307246604935 0.192237020630738 RHBDD2 other 0.527428678583968 1 1 3.64789761977447 -1.307246604935 0.121122832943273 -24.6667328773312 13.487352722967 -1.82887875656484 0.06851264777797 -44.7247421882535 24.6620634110626 -1.81350365712674 0.0708561867228398 SOX8 other 1 1 1 -1.82887875656484 -1.81350365712674 1.23264284000354e-13 212.139746053631 31.7263056877113 6.68655683210541 1.30045708193028e-10 -178.862351165883 77.0269639773479 -2.32207452988129 0.0209702422316011 IBTK other 1.56705884249651e-09 1 1.73298910738029e-06 6.68655683210541 -2.32207452988129 1.10674984064366e-11 118.239091357019 27.9494322961287 4.23046486612884 3.19018041140011e-05 -87.6382451530783 41.4803322189989 -2.11276623076172 0.0355319206336462 ZNF195 other 1.31083451125835e-07 1 0.313881850677657 4.23046486612884 -2.11276623076172 3.59410810439544e-18 843.499200255919 102.060217259475 8.26472079822673 8.38800521018576e-15 -215.583553262954 206.764221869919 -1.04265404968652 0.298119788819234 MYCBP2 other 5.10650879472505e-14 1 1.22330667985349e-10 8.26472079822673 -1.04265404968652 2.37840473953555e-09 311.113115802944 61.0659638446688 5.09470572828933 6.90560418409939e-07 -186.667226487523 123.713792074134 -1.50886350954035 0.132601466979303 FBXL3 other 2.5184927786942e-05 1 0.007740491729957 5.09470572828933 -1.50886350954035 0.0128904617301478 -223.39520524536 77.0422657943445 -2.89964479811235 0.00404651636462064 -127.733196023409 156.662354510597 -0.815340714254167 0.4156040204126 ITGAL other 1 1 1 -2.89964479811235 -0.815340714254167 5.64859317846889e-07 111.234594571992 26.6506137643669 4.17380986252249 4.04821960882012e-05 -120.041681629682 59.9127270384042 -2.00360904207773 0.046114740079627 PDK2 other 0.00513344148059253 1 0.394579965271697 4.17380986252249 -2.00360904207773 0.00593113823857977 1267.33394033173 586.708377287337 2.16007473114886 0.0316502746725888 3961.69436949174 1323.67584214503 2.99294906151023 0.00301973057001051 ITGA3 other 1 1 1 2.16007473114886 2.99294906151023 0.00423164570116098 22.7597128683362 7.15097630897362 3.18274203199016 0.0016282182015576 4.59683064744993 14.7926053448239 0.31075192910885 0.756227215377432 ITGA2B other 1 1 1 3.18274203199016 0.31075192910885 0.772300894671862 -12.7160330740252 20.0082226233092 -0.635540363251019 0.525626552374384 -37.3437237815143 84.5652485882759 -0.44159657075367 0.65914264592612 ASB4 other 1 1 1 -0.635540363251019 -0.44159657075367 1.57740653762086e-14 289.261543775307 87.0156206513917 3.32424846952672 0.00100925897572715 -835.814822918605 167.505228869263 -4.98978347458606 1.0843452692101e-06 GDE1 other 2.05709586571136e-10 0.0169710878084073 1 3.32424846952672 -4.98978347458606 0.0644122974768139 378.961420349611 162.375788127419 2.33385423233317 0.0203319359218066 290.510469011725 375.56857853965 0.773521763032833 0.439885387866967 CRLF1 other 1 1 1 2.33385423233317 0.773521763032833 0.0644797476327311 41.8085379259799 18.1943817044008 2.29788176401001 0.0223332637034083 11.5905412527121 38.4702069268631 0.301286168664162 0.76342818785108 OSBPL7 other 1 1 1 2.29788176401001 0.301286168664162 6.54007308315803e-08 293.473556912366 73.9654962351642 3.96770888928133 9.30525019611858e-05 -298.168790372536 146.150425070931 -2.04015000454379 0.0423083896702936 TMEM98 other 0.000633667681027181 1 0.875624043454759 3.96770888928133 -2.04015000454379 0.772970239064223 10.6057586822814 15.5935162383926 0.68013900906898 0.496997054155214 18.8749282169689 46.6543265640384 0.404569728191467 0.686112941620098 YBX2 other 1 1 1 0.68013900906898 0.404569728191467 0.75630176552692 -6.8863503791561 39.0548253640829 -0.176325212440694 0.860170149388468 -55.9691165986129 76.4463732150715 -0.732135669028423 0.464718452104967 KRT33A other 1 1 1 -0.176325212440694 -0.732135669028423 0.125676128833069 33.170711942195 29.9076985093651 1.10910279277451 0.268369103006412 -76.8817001017344 64.3484155560044 -1.19477223234536 0.233220623946999 MAP3K14 other 1 1 1 1.10910279277451 -1.19477223234536 0.25623251752319 15.7765227403426 19.7623163301424 0.798313440428012 0.425385069147538 -28.7414596662242 37.2927914331562 -0.77069746086829 0.441555190759924 ABCC8 other 1 1 1 0.798313440428012 -0.77069746086829 0.0519329172137175 133.838309191813 267.167772252347 0.500952296991118 0.616809837222173 -1179.1059767684 569.837125899201 -2.06919823784344 0.0394719233933221 TMEM132A other 1 1 1 0.500952296991118 -2.06919823784344 2.43909085254495e-14 1492.94383760879 210.582815398773 7.08958057561185 1.15998662857781e-11 -294.233210935517 407.16944753659 -0.722630867113566 0.470527559763861 AP2B1 other 3.16667165385911e-10 1 1.59312563568877e-07 7.08958057561185 -0.722630867113566 0.859468068835981 -17.861113366012 43.4380124947146 -0.411186247717603 0.681268297640087 -82.5027568765806 185.194400868826 -0.44549271732582 0.656327436514993 TAC1 other 1 1 1 -0.411186247717603 -0.44549271732582 3.69254232805646e-16 241.629032426055 36.6055353589326 6.60088781810677 2.12061842652284e-10 -113.334933334127 65.6159072081715 -1.72724782992884 0.0852542034762843 ZNF263 other 5.02813488811448e-12 1 2.80536611644706e-06 6.60088781810677 -1.72724782992884 0.323742377886295 277.537440882155 405.633919565401 0.684206688581444 0.494425048887421 -480.92108490353 712.034176594472 -0.675418541289249 0.499981569688516 CX3CL1 other 1 1 1 0.684206688581444 -0.675418541289249 6.02137944541964e-06 322.476532659624 71.9437794724867 4.48234072527351 1.09048766180025e-05 -104.93737563276 158.952112162719 -0.660182329161723 0.509697552564238 SPATA20 other 0.0502002404364635 1 0.111655031691728 4.48234072527351 -0.660182329161723 0.990415755087772 -0.0403766031394303 3.38502829425167 -0.0119279957594435 0.99049183824323 0.950560043623633 7.47795313847025 0.127115004068893 0.898943642616948 CACNA1G other 1 1 1 -0.0119279957594435 0.127115004068893 0.0295042621777257 159.505135845423 141.097608971164 1.13045952378982 0.259282137774534 -364.11015077485 254.452080221164 -1.43095765009417 0.1535944584536 TNFRSF12A other 1 1 1 1.13045952378982 -1.43095765009417 1.87549939951425e-07 87.6566437942343 15.7254987045892 5.57417258688613 6.11727342027352e-08 -12.4558231198573 63.8804011236874 -0.194986614059294 0.845552836089579 DLX6 other 0.00176478249083801 1 0.000731197691925294 5.57417258688613 -0.194986614059294 3.44843531263798e-05 89.6827171441166 28.0862746233463 3.19311543972332 0.00157289606421024 -73.4124063137499 51.1088881613275 -1.43639216102726 0.152039927152691 MAP3K9 other 0.268322751676361 1 1 3.19311543972332 -1.43639216102726 1.24387907594821e-13 243.228710831159 50.8415941934658 4.78404964851435 2.81563160447423e-06 -608.228558131803 131.263428230774 -4.63364827758785 5.56980816553121e-06 RALA other 1.58097030553017e-09 0.0861148040472781 0.030220174010822 4.78404964851435 -4.63364827758785 1.7274022127114e-12 448.248460279099 63.993524407695 7.00459092428418 2.04065463961898e-11 -525.698691462119 277.260935428657 -1.89604312864835 0.0590421033183276 BAIAP2L1 other 2.11088550393333e-08 1 2.78324886297632e-07 7.00459092428418 -1.89604312864835 9.78296575647568e-11 247.898581647538 42.9103240720384 5.7771314248609 2.06714040069245e-08 -195.295756659695 118.445599650929 -1.64882238964765 0.100334262186781 KDM7A other 1.11359499205963e-06 1 0.000252666571176638 5.7771314248609 -1.64882238964765 0.000279858452471551 214.743699554932 58.3421145569339 3.68076647865363 0.000280359765880541 -147.252247837176 151.455167896819 -0.972249741504323 0.331790122115668 ETV1 other 1 1 1 3.68076647865363 -0.972249741504323 9.24822454898778e-26 213.570794558464 21.1949166021083 10.0765102579937 1.64842743361277e-20 -129.348928781925 57.7145598720598 -2.24118366437624 0.025818074349308 AGK other 1.4234867225802e-21 1 2.52901736864872e-16 10.0765102579937 -2.24118366437624 0.684529847025576 -5.47632045732584 81.6802826221704 -0.0670458069134962 0.946595602410076 -293.822260286278 341.378974695829 -0.8606923157704 0.390182643410611 ALDH3B1 other 1 1 1 -0.0670458069134962 -0.8606923157704 0.44332286993618 -67.7833711048162 71.8634685664397 -0.943224317681641 0.346406290244177 -156.381098340754 127.150883782982 -1.22988605102943 0.219806400094588 TTC22 other 1 1 1 -0.943224317681641 -1.22988605102943 6.4535630374451e-09 210.209640571658 36.2858472723158 5.7931578390354 1.91871492131685e-08 -63.5869717193346 112.00219701615 -0.567729682214766 0.570690310662177 PHTF2 other 6.65233277899841e-05 1 0.000234850706369182 5.7931578390354 -0.567729682214766 0.00768935831196306 26.7756795498637 8.66719529559239 3.08931305187967 0.00221481242906261 10.4631401608922 28.085482213102 0.372546217348233 0.709777394799297 CCL26 other 1 1 1 3.08931305187967 0.372546217348233 7.39148580519577e-13 218.722005105295 51.4950549443934 4.24743706636453 2.98198651807789e-05 -293.538721792466 83.2052182557798 -3.52788836981478 0.000492421215994849 FARP2 other 9.15657261547652e-09 1 0.294530808390553 4.24743706636453 -3.52788836981478 0.00899253057436886 63.4163773690833 24.705209849411 2.5669232423296 0.0107958334788774 -1.56435944857295 46.6203567858688 -0.033555286926657 0.973256388263297 USH1C other 1 1 1 2.5669232423296 -0.033555286926657 1.14727614468651e-10 381.844506284103 69.836162184841 5.46771893440314 1.03220965004201e-07 -477.439011586848 190.758592933657 -2.50284406193379 0.012906862576436 GGCT other 1.30124060330344e-06 1 0.00121945248055963 5.46771893440314 -2.50284406193379 2.75234812600432e-13 149.956893302461 19.2748067764009 7.77994275335932 1.65780095109159e-13 20.9650249829394 66.5310818347916 0.315116249499733 0.752923267156273 DBF4 other 3.45942635957483e-09 1 2.37115270034629e-09 7.77994275335932 0.315116249499733 0.321606272898438 -1.99413192609444 4.65756243549482 -0.428149263421003 0.668882520120634 7.34773637551602 7.84465726906301 0.936654862474783 0.349770068215572 TBXA2R other 1 1 1 -0.428149263421003 0.936654862474783 1.29216589367425e-13 321.285802419361 45.4529552796916 7.06853493776919 1.35665963618096e-11 -203.121544666588 130.789927191776 -1.55303660631872 0.121594469151592 IFRD1 other 1.64130911814504e-09 1 1.85957336331324e-07 7.06853493776919 -1.55303660631872 8.98736816049127e-35 173.54903782259 13.8377700341175 12.5416911391574 9.25054689162166e-29 -59.4212323193969 37.3007357634049 -1.59303110523879 0.112318877473151 COX10 other 1.41937505358639e-30 1 1.45594357527233e-24 12.5416911391574 -1.59303110523879 3.00679883424302e-06 194.359806736044 41.0771904828428 4.73157497996909 3.59101583164461e-06 -72.4746789613984 138.268484473346 -0.524159060811643 0.600596345267968 GTF2IRD1 other 0.0257111368316121 1 0.0382012264170353 4.73157497996909 -0.524159060811643 4.67956653723066e-66 567.113369304624 24.5568616977427 23.0938861929883 7.04040236683222e-66 -106.578339802563 185.882647840758 -0.573363576646846 0.566875783877446 PAF1 essential 7.46344067022918e-62 1 1.12308498555708e-61 23.0938861929883 -0.573363576646846 1.31060763491115e-17 269.084779284517 37.8246458650574 7.11400657244747 9.99296749362004e-12 -347.98302216769 97.6471883735817 -3.56367682432766 0.000431749915079682 VPS41 essential 1.84402494231999e-13 1 1.37503232712212e-07 7.11400657244747 -3.56367682432766 0.189455876813883 21.203342095381 41.3805771472478 0.512398413872563 0.6087926553236 -164.386155964451 118.532987165922 -1.38683888675095 0.166639025426596 ARHGAP44 other 1 1 1 0.512398413872563 -1.38683888675095 1.00376223364937e-34 646.119777150885 49.6147707530491 13.0227302745559 2.16304279797639e-30 -88.0249765859256 139.57529541416 -0.63066301471711 0.528796311048543 ELAC2 essential 1.58514131937908e-30 1 3.41393044804614e-26 13.0227302745559 -0.63066301471711 0.33541696341985 105.856393760465 88.589397701053 1.1949104126171 0.233162879545606 -135.699048206574 229.91725999185 -0.590208182767074 0.555541096885037 SCIN other 1 1 1 1.1949104126171 -0.590208182767074 1.95525752072342e-31 912.951224177504 70.2237920243793 13.0005970606167 2.33203963151058e-30 -537.328400247519 331.861690687895 -1.61913355872359 0.106581669159783 ADIPOR2 other 3.07190509080857e-27 1 3.68019174248684e-26 13.0005970606167 -1.61913355872359 2.58804710797394e-05 4.47736578136875 3.0857037642052 1.45100311744345 0.147927056966909 -15.6465701558634 4.94399917895844 -3.16475986129912 0.00172773837598493 CDKL3 other 0.204171036348064 1 1 1.45100311744345 -3.16475986129912 0.00127956236127506 259.464332577512 75.8436270063717 3.4210433073792 0.000720028273828207 92.8633268124782 137.326962459678 0.676220642685114 0.49947726543968 PRSS21 other 1 1 1 3.4210433073792 0.676220642685114 7.88179604265816e-15 217.240339039546 34.9037674533057 6.22397967010783 1.82658424735339e-09 -330.116906930786 98.5919629057247 -3.34831458063625 0.000927883153143358 MARK4 other 1.0366138155304e-10 1 2.33747986133814e-05 6.22397967010783 -3.34831458063625 0.0671303847210587 286.194494996416 131.102603399498 2.18298102078355 0.0299018032554659 158.041941874425 192.057334354586 0.822889385638562 0.411299771989426 PROM1 other 1 1 1 2.18298102078355 0.822889385638562 4.46827166631221e-12 274.8194258059 46.9036115849156 5.85923805266805 1.33553137689086e-08 -180.4055588867 107.379078623714 -1.68008108468588 0.0940854257920399 CCDC124 other 5.36281965390791e-08 1 0.000164911414418484 5.85923805266805 -1.68008108468588 0.517295609518511 -0.328003338664304 3.50139868468178 -0.0936778037014984 0.925434068815008 -11.4807195055041 10.2790086429037 -1.1169092180334 0.26501877310639 CEACAM21 other 1 1 1 -0.0936778037014984 -1.1169092180334 1.74044089467917e-18 770.944122298365 93.5485587513937 8.24111170271642 7.28902521667484e-15 -818.081180811809 286.385445715262 -2.85657386941788 0.00461289283038136 PAFAH1B1 essential 2.48830834712281e-14 1 1.06405190113019e-10 8.24111170271642 -2.85657386941788 0.486855568322028 -532.980840145495 452.34436620782 -1.17826346465566 0.23979862848291 -756.217087575597 1059.71289965121 -0.713605626414945 0.476128833269657 NOS2 other 1 1 1 -1.17826346465566 -0.713605626414945 0.847204528958055 12.7794317914139 33.480158797401 0.381701648093914 0.702984016779104 -24.8660617013131 97.1480751775515 -0.255960415642482 0.798177026559016 DNAH9 other 1 1 1 0.381701648093914 -0.255960415642482 7.5921368792084e-17 1135.24987341909 152.899313131625 7.42481996921593 1.6603322198308e-12 -633.591390341029 345.480059181213 -1.83394489349874 0.0678184162714767 KIAA0100 other 1.0511313509264e-12 1 2.32745370575882e-08 7.42481996921593 -1.83394489349874 0.199468381577374 -118.001656380468 68.7018762863481 -1.71759001004047 0.0870180048439058 -224.294835723361 207.175838117809 -1.08263028044717 0.27993847151848 GAS7 other 1 1 1 -1.71759001004047 -1.08263028044717 3.93453729930835e-12 186.266007527493 25.8215230973837 7.21359490782193 5.42215384875785e-12 21.0630123898051 72.5792773898742 0.290206972944369 0.771879025334957 TRAPPC6A other 4.73796981582712e-08 1 7.50697200360525e-08 7.21359490782193 0.290206972944369 0.806939363161496 -0.886559284417253 11.766890069501 -0.075343551200088 0.939996754744377 9.67647286300355 19.7720201259116 0.489402337312126 0.624951314852993 MATK other 1 1 1 -0.075343551200088 0.489402337312126 0.449853064536049 -17.5145210350371 23.6305435496093 -0.74118147127118 0.459225182927388 -84.2032541088364 69.7080898799511 -1.20794091839051 0.228123067270717 CEACAM7 other 1 1 1 -0.74118147127118 -1.20794091839051 0.457256845060487 -17.3467787484119 21.1961606123651 -0.818392494077081 0.41385213494862 -52.3462613353737 46.9685364495306 -1.11449632652748 0.266053736678796 CD79B og 1 1 1 -0.818392494077081 -1.11449632652748 0.0142917505509478 3.46836360371455 1.77546638538974 1.95349437886045 0.0517860783404663 -6.5980414037248 3.93326828690998 -1.67749589461854 0.0945942349843386 SCN4A other 1 1 1 1.95349437886045 -1.67749589461854 9.47765580457448e-09 32.0527750621787 28.808976587704 1.11259679650888 0.26686037905342 -173.469078118187 42.4854107045645 -4.08302697894244 5.84431812214883e-05 ST7L other 9.67384327972918e-05 0.879803650108285 1 1.11259679650888 -4.08302697894244 0.000907859866085608 103.977181217386 28.552646855119 3.64159518187522 0.000326490321885355 41.9901911513776 56.6348700545688 0.741419396052631 0.459103229947178 PAX6 other 1 1 1 3.64159518187522 0.741419396052631 1.6897063547764e-13 162.741771936063 33.4662335283356 4.86286488732803 1.96336307185755e-06 -162.256873201293 61.26024570477 -2.64864874984755 0.00855552609196586 RPUSD1 other 2.13866133324048e-09 1 0.0213260496865167 4.86286488732803 -2.64864874984755 0.000912854429732464 50.9338855534504 45.0671619666547 1.13017734711444 0.259443019487564 -196.319888699822 82.426759666074 -2.38174944029282 0.0179505393367572 RHBDF1 other 1 1 1 1.13017734711444 -2.38174944029282 0.000974516822500134 132.147632047728 52.4911248140573 2.51752334353366 0.0124153834358831 -90.6586809457046 95.7864424882499 -0.94646672943121 0.344782665632993 LUC7L other 1 1 1 2.51752334353366 -0.94646672943121 0.839301302540128 113.927900722974 251.598929706344 0.452815522132571 0.651045229005827 303.19460118732 594.181701329006 0.510272531969875 0.610277438857907 CACNA2D2 other 1 1 1 0.452815522132571 0.510272531969875 0.00541459415495588 6.06990626171163 32.0476940825534 0.189402277932254 0.849918795443975 -152.003487688057 58.6002516488205 -2.59390503301902 0.0100034000335378 BAIAP3 other 1 1 1 0.189402277932254 -2.59390503301902 3.91788244442928e-17 173.435373879931 34.2135240719666 5.06920519251736 7.39381688812324e-07 -229.090656633146 62.5605422732018 -3.6619033069232 0.00030078059394882 TSR3 other 5.46270349226774e-13 1 0.00827072357105465 5.06920519251736 -3.6619033069232 1.08716887382102e-13 141.824038768813 41.9099761536478 3.38401621248523 0.000820726299150239 -327.240165940499 76.8849352588091 -4.25623257454724 2.87424874026593e-05 PIGQ other 1.38429212703631e-09 0.437144490907046 1 3.38401621248523 -4.25623257454724 2.25819460872255e-10 191.248802775205 43.1789057378705 4.42921837658957 1.3716228868022e-05 -154.763176525893 78.9540344351136 -1.96016806022852 0.0509969025332467 CRAMP1 other 2.52646812823878e-06 1 0.139233439239291 4.42921837658957 -1.96016806022852 2.18792253573268e-11 342.391187082084 59.3084623256164 5.77305790196147 2.11218254203843e-08 -221.633353110017 115.692199060634 -1.91571562222497 0.0564457703284063 TEAD3 other 2.56030695131438e-07 1 0.000258003097509994 5.77305790196147 -1.91571562222497 0.301026263097127 -56.4053781433212 49.9949508214549 -1.12822149470173 0.260220543670271 -194.012700876845 171.087084487299 -1.13399969061514 0.257793122846561 SELE other 1 1 1 -1.12822149470173 -1.13399969061514 2.11520620212603e-19 369.601847366938 53.7547661625988 6.87570375153259 4.27348736669887e-11 -215.658282174035 86.3810572134624 -2.49659229848399 0.0131357267732365 DNAJC11 essential 3.06641443122211e-15 1 5.77477829823004e-07 6.87570375153259 -2.49659229848399 0.0492237747184397 -533.05303395208 237.51879514432 -2.24425622245258 0.0256261947925176 -902.608853455518 787.38616639161 -1.14633567616757 0.252671195418015 FMO3 other 1 1 1 -2.24425622245258 -1.14633567616757 0.00130542347852724 290.143534298408 94.0912602268951 3.0836395813888 0.00225520618388463 -147.357041233155 177.845543674259 -0.828567520944202 0.408075627763322 MYLIP other 1 1 1 3.0836395813888 -0.828567520944202 3.93005140710872e-05 71.5163817691607 29.3824262707825 2.43398489662086 0.0155775521316372 -74.6337093382132 43.4525123792047 -1.71759249929887 0.0870091196714143 E2F2 other 0.304185978910215 1 1 2.43398489662086 -1.71759249929887 1.07124471131649e-16 1674.64454444695 198.999558663723 8.41531788156791 2.31631667658176e-15 -335.268045979183 375.1256692414 -0.8937486113845 0.372252361081961 PSMB1 essential 1.47671083454978e-12 1 3.40452225123988e-11 8.41531788156791 -0.8937486113845 1.34993201928124e-06 284.884000194255 63.7287713172304 4.47025722143854 1.14789545390616e-05 -137.425575621454 120.356430533879 -1.14182162940408 0.254532350852186 JARID2 other 0.0119050504780413 1 0.117314915389209 4.47025722143854 -1.14182162940408 0.341904088119701 -2.4756925896191 1.95427153911351 -1.26681095235216 0.206322713353555 -4.78577347421233 5.37159530025718 -0.890940811193129 0.373760065954281 CAMK1G other 1 1 1 -1.26681095235216 -0.890940811193129 8.60216989129133e-07 139.042831815559 50.6759972014431 2.74376113927955 0.00648398857207299 -192.870587228722 80.1894888479236 -2.4051853927451 0.0168424542210505 CDK11A other 0.00769722161872748 1 1 2.74376113927955 -2.4051853927451 4.18582163979762e-10 283.827156502771 66.2637385272661 4.28329525032734 2.5686427060015e-05 -221.302490582474 104.855466396281 -2.11054795890283 0.0357377140089163 NADK other 4.61737985086075e-06 1 0.255066220705949 4.28329525032734 -2.11054795890283 0.844753170144206 15.207784602614 31.4377471464993 0.483742824565197 0.62896638187128 -13.0892273608298 80.1461430170621 -0.163316996527746 0.870392863481068 TFAP2B other 1 1 1 0.483742824565197 -0.163316996527746 0.000773883169684823 136.615302438664 36.5541778487673 3.737337576128 0.00022667142010716 52.8992337729302 114.104798997733 0.463602181832694 0.643303553539131 DLEC1 other 1 1 1 3.737337576128 0.463602181832694 0.000610186203463504 103.950582921962 30.7149734216951 3.38436180604141 0.000818514515600445 -94.6559439580145 81.3657721672228 -1.16333860586338 0.245711675025232 CYTH3 other 1 1 1 3.38436180604141 -1.16333860586338 0.621900998921797 6.07307693801685 16.6859404465566 0.363963718884668 0.716178641649981 -43.6542419983054 57.4311414141001 -0.7601144766311 0.447869607479024 ADAM22 other 1 1 1 0.363963718884668 -0.7601144766311 1.11590805271268e-10 975.435739560452 165.953545824583 5.87776377246866 1.2272908037423e-08 -1345.10459567377 594.626350206374 -2.26210055307325 0.0244893445082809 SYPL1 other 1.26633245821835e-06 1 0.00015177905369881 5.87776377246866 -2.26210055307325 0.00979499992977381 127.442381595257 69.2442455953882 1.84047613631226 0.0667916465884993 -302.975257319048 153.93982545043 -1.96814083965951 0.0500711582128097 CYB561 other 1 1 1 1.84047613631226 -1.96814083965951 1.85061092414924e-10 452.657422033429 72.3181229193913 6.25925291974155 1.5064511985832e-09 -146.654220120819 159.75982687403 -0.917966819258355 0.359452490335769 SPAG9 other 2.07786594563477e-06 1 1.93413269386098e-05 6.25925291974155 -0.917966819258355 0.0116161053552531 49.9681720186086 20.2334773821735 2.46957905825089 0.0141507245619352 -37.7117219882392 55.3411569606883 -0.681440794868597 0.496181033882917 AASS other 1 1 1 2.46957905825089 -0.681440794868597 3.38693144064828e-09 170.257739800444 28.4348128849787 5.98765114049288 6.76313411764261e-09 -166.873720911825 131.961488866823 -1.2645637931551 0.2071181987742 PLEKHG6 other 3.54668648772464e-05 1 8.45662290070032e-05 5.98765114049288 -1.2645637931551 6.73139863158005e-13 106.665648854961 16.6277299849911 6.41492548599494 6.2205898527685e-10 -97.0782325308295 43.7066794297181 -2.22113035804824 0.0271657177326558 SS18L2 essential 8.35299256192769e-09 1 8.09485357540765e-06 6.41492548599494 -2.22113035804824 9.33017543699453e-19 86.8310525747266 20.8769297132291 4.15918689996375 4.28149780384689e-05 -179.402456676389 37.4328711203888 -4.79264484146589 2.70659768445599e-06 MPND other 1.3383203646825e-14 0.0421038335793973 0.416504106358226 4.15918689996375 -4.79264484146589 0.0170245765063314 757.246445168647 266.144241717095 2.84524827696097 0.00478026637527456 342.083454506919 1129.29194771485 0.302918528020264 0.762186943762544 MGST1 other 1 1 1 2.84524827696097 0.302918528020264 0.00450377403315918 54.9133558890988 26.2888608360292 2.08884501430504 0.037651264434647 -107.245967482013 58.4501432380041 -1.83482813797935 0.0676231769811488 CRY1 other 1 1 1 2.08884501430504 -1.83482813797935 0.0742163803497777 -8.22890756765517 127.535480805841 -0.0645224961372344 0.948601939799429 -586.511446320618 284.879109259756 -2.0588082005895 0.0404718527585272 NFIX other 1 1 1 -0.0645224961372344 -2.0588082005895 0.879574637017848 51.0100721141712 101.53518436542 0.50238813700863 0.615800999618816 6.67482462894026 426.625589523595 0.0156456264997932 0.987528575268239 ST3GAL1 other 1 1 1 0.50238813700863 0.0156456264997932 0.749196302381001 -4.19887037516961 10.7208370325015 -0.391655088351797 0.695619737962947 -14.6505907282345 19.2749953969384 -0.760082709568977 0.447863454886955 MMP25 other 1 1 1 -0.391655088351797 -0.760082709568977 0.0257599761591513 -725.739363080631 268.758468608357 -2.70034044634404 0.0073612965882568 -845.440953854598 483.20091328779 -1.74966754119329 0.0813034309178167 IL32 other 1 1 1 -2.70034044634404 -1.74966754119329 0.363773177636081 42.9341981747663 45.2508528954723 0.948804175557589 0.343597902507958 -52.1435191514775 95.6428774780053 -0.545189778125076 0.586088578936735 MAPK8IP2 other 1 1 1 0.948804175557589 -0.545189778125076 0.118946659740333 -139.172696327862 181.97397399702 -0.764794510286078 0.445054506933145 -603.031946490546 303.416758862141 -1.98747079347893 0.0478692945727775 RHOBTB2 other 1 1 1 -0.764794510286078 -1.98747079347893 0.000107964643649429 109.81494886284 25.6023375832752 4.28925478017981 2.49322544589358e-05 93.0132131571166 94.5622981012165 0.983618366143748 0.326177304085193 HEATR5B other 0.796887034776437 1 0.247826609321822 4.28925478017981 0.983618366143748 6.27566770721865e-30 661.075464488706 50.0673071170585 13.203735182783 8.29185719254248e-31 847.084638268549 488.561513932573 1.73383415212164 0.0841329022524188 SEC62 other 9.82895076304585e-26 1 1.30961592499016e-26 13.203735182783 1.73383415212164 2.06841462617638e-07 2358.45173042567 438.302611624567 5.38087537668114 1.65440816590551e-07 -4.67806162856263 1350.84170710535 -0.0034630716566984 0.9972395297047 RPS20 essential 0.00194182765105439 1 0.00193185241532786 5.38087537668114 -0.0034630716566984 1.78791926560808e-30 2067.42749050454 537.14257222049 3.84893619948614 0.000147798057921303 -5759.12684551046 788.857026459215 -7.30059649891224 3.13956861897296e-12 CSDE1 other 2.8038149923266e-26 5.01043755901895e-08 1 3.84893619948614 -7.30059649891224 2.37731585231246e-18 508.449387460298 86.4475347888544 5.88159498940219 1.21603318572625e-08 -934.211831850608 220.517684397759 -4.23644858416672 3.13277657335366e-05 UBE3C other 3.38910147905664e-14 0.475774778195221 0.000150435465406195 5.88159498940219 -4.23644858416672 4.92272811543369e-05 174.397248764786 41.6299573845383 4.18922477277286 3.79445195378701e-05 0.719719124541726 76.5152493574084 0.00940621811450767 0.992501980680079 REV3L essential 0.377228655485684 1 0.37056617780684 4.18922477277286 0.00940621811450767 0.142095454194935 63.253744400896 33.235880958359 1.90317640384337 0.0580731853035955 78.2001647918153 50.0457850022676 1.56257244817465 0.119315882856717 PAX7 other 1 1 1 1.90317640384337 1.56257244817465 2.96912901411433e-07 10.9104065784554 2.9008238125451 3.7611407253593 0.000206969504311761 -6.65475603179724 4.54242401225723 -1.46502308323488 0.144065300592395 MASP2 other 0.00275921159281644 1 1 3.7611407253593 -1.46502308323488 0.748123860704883 -2.58879995093079 6.29317865201394 -0.411366035207394 0.681128091834074 5.36366669733492 11.569183552309 0.46361669975099 0.643293163435274 IYD other 1 1 1 -0.411366035207394 0.46361669975099 4.89233377204027e-17 35.7328444211626 14.2308027718909 2.51095071683118 0.0126252525549499 -124.988435346739 20.8057995229383 -6.00738439342067 6.07575740603275e-09 FAM76A other 6.802790110022e-13 9.65984669985147e-05 1 2.51095071683118 -6.00738439342067 0.562609129375678 -7.77673494894954 24.6592797826774 -0.315367481024833 0.752728082196794 -71.6539504907117 67.7795632476142 -1.05716158466444 0.291389827885928 TRAF3IP3 other 1 1 1 -0.315367481024833 -1.05716158466444 1.45322262230878e-07 103.27941757547 24.6431275971963 4.19100283306656 3.75455165925208e-05 -75.5374447674218 46.4367727352059 -1.62667300757861 0.104960226291498 POMT2 other 0.00137692843463757 1 0.366894788142113 4.19100283306656 -1.62667300757861 3.18235907473782e-14 355.166308926474 56.1676478848393 6.32332530026312 1.0508515622966e-09 -306.565385929008 100.562192165175 -3.04851534486707 0.00252712413921348 VTA1 other 4.12051852997053e-10 1 1.35685953723737e-05 6.32332530026312 -3.04851534486707 0.0178937619696045 35.1586114295486 12.4172145564824 2.83144108283078 0.00498255923177243 53.8949219599424 42.11205946747 1.27979782137167 0.201714812177724 MLXIPL other 1 1 1 2.83144108283078 1.27979782137167 1.40009729751712e-17 734.045882295761 87.8196614854179 8.35855968788545 3.44012913870448e-15 -462.860716057972 297.026002363564 -1.55831715868237 0.120333774819331 BAZ1B other 1.96923684895783e-13 1 5.04460536899625e-11 8.35855968788545 -1.55831715868237 6.31041056591895e-16 376.798350165245 45.484758148332 8.28405746242408 5.46687801562608e-15 -15.1137752805591 86.1964429908355 -0.175341055339906 0.860942110161281 RANBP9 other 8.54240278308448e-12 1 7.9974958490594e-11 8.28405746242408 -0.175341055339906 0.464965641727432 10.6218867096289 17.8929660573447 0.593634765504337 0.553247952158209 -27.4381639037343 35.0347248056563 -0.783170527410692 0.4342058483515 ETV7 other 1 1 1 0.593634765504337 -0.783170527410692 1.99238212769069e-11 92.7096896351784 12.7421869782876 7.27580671929815 3.6906020522233e-12 -6.5338977684574 35.9344671322574 -0.181828152464576 0.855853020036563 SPRTN essential 2.3362672829301e-07 1 5.13436557505305e-08 7.27580671929815 -0.181828152464576 8.66679142228521e-16 271.487748375116 30.8085891225829 8.812079881195 1.53252358617078e-16 -50.1220241411327 99.8952198865307 -0.501745971409498 0.616255107213318 METTL13 other 1.16958350243739e-11 1 2.28499266698063e-12 8.812079881195 -0.501745971409498 6.26880731336498e-07 72.2303272954098 13.1589907214248 5.48904766516845 9.3138177751904e-08 60.7773818252456 60.1615771007792 1.0102358474319 0.313286777621187 DYRK4 other 0.00567515126078932 1 0.00110331485364906 5.48904766516845 1.0102358474319 4.2034283868498e-11 1262.74655107962 194.949788116943 6.47729122086631 4.35422877287142e-10 -439.156174235012 464.136311768624 -0.946179307888186 0.344896918843234 UQCRC1 essential 4.86252595790785e-07 1 5.69794377217954e-06 6.47729122086631 -0.946179307888186 0.00222194979981426 78.7967393039392 39.3728969378225 2.00129392125691 0.0463503808977841 -211.869626823189 101.653410232753 -2.08423530836867 0.0380684390540961 STARD3NL other 1 1 1 2.00129392125691 -2.08423530836867 1.29724982861952e-10 6270.83605827805 959.796213114644 6.53350781404784 3.18437140834134e-10 -5855.41976327801 4448.75572810965 -1.31619268872874 0.18922566710528 CD9 other 1.46718955616868e-06 1 4.18521934198303e-06 6.53350781404784 -1.31619268872874 2.89119576739936e-26 1932.85778628917 163.572487614061 11.8165213140832 3.00416320705942e-26 -364.505155174154 772.880192246456 -0.471619222268696 0.637579483207055 NCAPD2 essential 4.45880211248329e-22 1 4.70662249649999e-22 11.8165213140832 -0.471619222268696 0.244077684832899 -11.7033102018707 8.77883420297499 -1.3331280590656 0.183613520270583 31.2914834418819 41.4800017133922 0.75437517235635 0.45128140794067 IFFO1 other 1 1 1 -1.3331280590656 0.75437517235635 0.073999855393598 -9.20226094453449 4.45811537877081 -2.06415944018742 0.0399473166587886 -20.8755097383362 12.3715556465323 -1.68737952887822 0.092672548716666 GIPR other 1 1 1 -2.06415944018742 -1.68737952887822 2.81740012280478e-05 20.2362560348856 4.67827753743513 4.32557835078338 2.1407205626344e-05 -2.7843015106681 11.4078566025787 -0.244068768364314 0.807362234873595 PHF7 other 0.221363127648772 1 0.213857984207176 4.32557835078338 -0.244068768364314 0.480080475804454 -84.072262887401 69.6769045671599 -1.2066015763712 0.228637846832076 -87.0993303223806 169.905297292282 -0.512634577676213 0.608624536165531 SEMA3G other 1 1 1 -1.2066015763712 -0.512634577676213 0.000117852314962903 255.932409282044 105.923769607751 2.41619430869761 0.0163450115878095 -671.92308051706 258.292323364871 -2.60140553835927 0.00979446907115861 NISCH other 0.865271696457632 1 1 2.41619430869761 -2.60140553835927 0.0122565713565358 -351.453667653016 146.012156999602 -2.40701647640185 0.0167525256175965 -877.643856097186 356.046800549137 -2.46496768049476 0.0143229525137334 STAB1 other 1 1 1 -2.40701647640185 -2.46496768049476 4.21508476167748e-05 66.5129932227348 19.7257094756885 3.3718935840919 0.000854491980724171 -63.2034426842959 41.0557380540715 -1.53945454837653 0.124851612091899 FUZ other 0.325235940211035 1 1 3.3718935840919 -1.53945454837653 0.00328803357112723 56.1915900402158 17.3595279417695 3.23693076382629 0.00136258276371854 37.2993611496043 49.0969847085484 0.759707777799845 0.44810713355074 PRSS3 other 1 1 1 3.23693076382629 0.759707777799845 2.98703274139163e-11 66.0156656432397 11.5910218531237 5.6954137848898 3.18896649745729e-08 -17.8558509726567 20.8227544357799 -0.857516282378803 0.391914547188229 ZNF200 other 3.47541259460916e-07 1 0.000386279511837002 5.6954137848898 -0.857516282378803 0.503364822966642 -58.7396028749277 86.4450203714673 -0.679502447017941 0.49739739908594 330.30667560801 408.808562695465 0.807973965687373 0.419811621791933 CD4 other 1 1 1 -0.679502447017941 0.807973965687373 3.68626380577125e-05 51.6232258636533 11.2441116196506 4.5911342407376 6.74364565173864e-06 28.5419220414408 53.1747125544544 0.536757429806735 0.591873936780353 LRRC23 other 0.286090933965907 1 0.0702283258172061 4.5911342407376 0.536757429806735 0.00130454044787319 54.7095001541855 23.5692083657259 2.32122773515565 0.021016596655479 -74.2612679418415 41.3993270247011 -1.79377959205794 0.0739630990550442 HFE other 1 1 1 2.32122773515565 -1.79377959205794 1.28566827799246e-19 276.958766160113 31.5030718527948 8.79148444489051 1.74121266693447e-16 -56.4103780638054 63.3202985915469 -0.890873532162024 0.373787258424056 SCMH1 other 1.86936167620104e-15 1 2.59510335879914e-12 8.79148444489051 -0.890873532162024 0.101929451327072 95.2069800066179 65.721869817111 1.44863468236003 0.148599956407765 -107.065221271531 116.640487333021 -0.917907869896392 0.35948631826374 FYN other 1 1 1 1.44863468236003 -0.917907869896392 0.00541435389202954 80.6132763975156 65.002944424035 1.24014807501102 0.21598938172454 -279.772903726708 115.617011251178 -2.41982473598891 0.0161838089687846 HIVEP2 other 1 1 1 1.24014807501102 -2.41982473598891 0.858058542548634 36.1517732388029 81.4923793649202 0.443621520448144 0.657671529949174 95.7588253910124 270.151135362938 0.354463901335687 0.723267936040833 FMO1 other 1 1 1 0.443621520448144 0.354463901335687 3.31174658715242e-22 409.426128892549 75.8598664583272 5.39713748530604 1.47486323414968e-07 -506.042092777349 112.186167200327 -4.51073519495258 9.61791595105073e-06 ELOA other 4.96653075300767e-18 0.148029344402622 0.0017263274155722 5.39713748530604 -4.51073519495258 5.65426213741236e-17 274.130340121192 81.4609967702736 3.36517291697598 0.00087514121325098 -604.719131768182 120.469458102665 -5.01968832011212 9.36882046203422e-07 LYPLA2 other 7.85037755158332e-13 0.0146762572537766 1 3.36517291697598 -5.01968832011212 4.18743766607133e-11 141.113939861075 27.2505850318452 5.17838203092405 4.35980852895788e-07 -60.5306591508489 42.6432449236747 -1.41946653588839 0.156908046333775 CLCN6 other 4.84444663587792e-07 1 0.00495448641230774 5.17838203092405 -1.41946653588839 0.0299952808262838 -430.7345265136 217.592766667334 -1.97954432544225 0.0487665190400343 589.733757459262 474.56961243267 1.24267071049125 0.215063358849192 MRC2 other 1 1 1 -1.97954432544225 1.24267071049125 1.61708804193235e-09 3117.93216908269 528.042415969197 5.90470021875017 1.05435834026057e-08 -1088.4724941771 1154.21693103086 -0.943039791666331 0.346500489983207 NME1-NME2 other 1.72769686400052e-05 1 0.000130793152109324 5.90470021875017 -0.943039791666331 0.000310535848896882 224.98131999841 69.7193449200869 3.22695688343437 0.00140428670021992 -614.375037537607 329.72248961327 -1.86330947051323 0.0634963826009521 TSPAN9 other 1 1 1 3.22695688343437 -1.86330947051323 1.36186226121149e-16 222.114748032094 34.8715576864975 6.36951036225428 8.05361064392539e-10 -212.055734523499 70.0956523220271 -3.02523376983913 0.00272211924182502 BTBD7 other 1.87296916784416e-12 1 1.04382847555917e-05 6.36951036225428 -3.02523376983913 5.76953358247545e-13 67.7082184410518 19.5745162310384 3.45899830380942 0.000629192241562929 -126.217494451544 32.8912504994184 -3.8374185394312 0.000154646933657713 APBA3 other 7.17499196316647e-09 1 1 3.45899830380942 -3.8374185394312 2.51264538768971e-20 137.383361440685 14.2897883813571 9.61409348930039 4.90578524573928e-19 -30.9515000341505 30.6469943529174 -1.00993590685359 0.313420274594569 MKS1 other 3.68780963551219e-16 1 7.46856745811348e-15 9.61409348930039 -1.00993590685359 1.6002314317479e-07 74.6604228895983 29.6012315463075 2.52220664443644 0.0122332367036236 -314.882785715338 77.764742159479 -4.04917160362443 6.70779552091913e-05 ABHD5 other 0.00151077849471319 1 1 2.52220664443644 -4.04917160362443 1.42073151883826e-08 248.975756126199 46.1488922646853 5.39505379020166 1.4864393929295e-07 -40.0295468962263 103.854997708762 -0.385436885844242 0.700213909812906 AKAP8L other 0.000143280773674839 1 0.00173928273366681 5.39505379020166 -0.385436885844242 9.24539949574793e-10 167.096792279934 28.7018369845294 5.82181525071029 1.64217853213385e-08 -82.3005406713809 62.7376612131176 -1.3118203496909 0.19069093302769 MBTD1 other 1.00053713342984e-05 1 0.000201807319813928 5.82181525071029 -1.3118203496909 2.35041801690221e-18 267.921942267461 32.1915432843123 8.32274302294869 4.26827014534452e-15 -150.741885606878 70.3656054344952 -2.14226658999199 0.0330632097970069 UTP18 essential 3.35122600849918e-14 1 6.25258893591519e-11 8.32274302294869 -2.14226658999199 3.56670304671937e-13 330.715964352112 48.4651430417351 6.82379012205371 5.71392615191431e-11 -345.886292943174 129.093162342095 -2.6793540933375 0.00782439712462208 RNF216 other 4.46551221449265e-09 1 7.69722991924377e-07 6.82379012205371 -2.6793540933375 8.03080901514449e-18 269.391138179309 37.0073050973164 7.27940436275767 3.58133600237754e-12 -273.714543601513 96.4030248695519 -2.83927339387837 0.00486153693971418 TTC19 other 1.13435177338916e-13 1 4.98378718090859e-08 7.27940436275767 -2.83927339387837 0.0214357134968225 6.56506276311049 3.08483941442023 2.12817002156475 0.0342493795899432 -23.4828488394384 16.9745533025115 -1.38341483401298 0.167706408949119 DPF1 other 1 1 1 2.12817002156475 -1.38341483401298 0.803263784115068 75.1340610964038 113.669421177767 0.660987452191757 0.509183961381729 60.1320384306497 232.159283214271 0.259011992103503 0.795823346346636 SYT7 other 1 1 1 0.660987452191757 0.259011992103503 3.47214864330007e-09 170.678345126202 28.3203542667753 6.02670233283194 5.40406150219709e-09 -15.8457099775886 74.4210829635842 -0.212919637105284 0.831548550452886 LARS2 essential 3.63325634034919e-05 1 6.78642043445911e-05 6.02670233283194 -0.212919637105284 5.75890674565165e-22 341.882366530825 50.5772370535955 6.75960939045643 8.41050003945409e-11 -321.337598997738 95.4425747060921 -3.3668161194024 0.000870152711831178 PIK3C2A other 8.61647627284399e-18 1 1.12658648028488e-06 6.75960939045643 -3.3668161194024 0.113114013596543 57.9518549320649 95.3864345356272 0.607548182445373 0.543994056008161 -435.134077503868 263.400348907072 -1.65198747575458 0.0996910020821529 PLAUR other 1 1 1 0.607548182445373 -1.65198747575458 9.7822897835276e-09 501.284420027596 90.5588656141122 5.5354538357808 7.2837931599138e-08 -219.238643850472 236.520809718792 -0.926931732185139 0.354780711766336 ANLN essential 9.97793557919815e-05 1 0.000867281251550936 5.5354538357808 -0.926931732185139 1.12300985144118e-16 329.811267421887 58.0621166110299 5.68031767824382 3.43994375307223e-08 -517.329011205405 130.664912887168 -3.95920373552868 9.59879123580145e-05 WIZ other 1.54728297331565e-12 1 0.000416129995809148 5.68031767824382 -3.95920373552868 0.544666462347754 -115.026245091971 1659.51446424413 -0.0693131922440718 0.94479163105523 4001.07770200454 3838.19652637973 1.04243690350542 0.298141643991534 DCN other 1 1 1 -0.0693131922440718 1.04243690350542 5.81472653675173e-15 100.763059559568 13.3486165538511 7.54857697448035 6.60747162018207e-13 -39.6984792566177 37.0432657007016 -1.07167871151991 0.284810840781856 QPCTL other 7.67892786443434e-11 1 9.34428636526148e-09 7.54857697448035 -1.07167871151991 2.2689046379293e-33 438.691913129422 39.1623024881358 11.2018927707921 3.46340243377241e-24 -326.731570221208 96.9420284393051 -3.3703809945113 0.000859839391602013 PPP5C other 3.57738194262313e-29 1 5.39840537352105e-20 11.2018927707921 -3.3703809945113 3.55237781503718e-06 141.693786154314 28.5546643765366 4.96219406699607 1.24809914746646e-06 -185.70980976561 168.173625068598 -1.10427428611269 0.270475841585848 CEP68 other 0.0302023161834461 1 0.013747812109343 4.96219406699607 -1.10427428611269 3.03423430375134e-10 198.879657214225 29.3203812204579 6.78298333568256 7.28035041550781e-11 213.979356886376 111.765707454509 1.91453498358135 0.0565969982631803 MAP4K3 other 3.37194458175887e-06 1 9.76877418752838e-07 6.78298333568256 1.91453498358135 0.262240080804778 0.722037152794969 1.15207281417762 0.626728748312997 0.531368571290035 -6.08087834826954 4.60924525553171 -1.31927853935992 0.188197846181162 ZBTB32 other 1 1 1 0.626728748312997 -1.31927853935992 0.984340503634731 -11.6740648460808 78.3244100747663 -0.149047593654865 0.881628171938835 -40.0912632306851 310.081528150136 -0.129292652386806 0.897223065404875 TYROBP other 1 1 1 -0.149047593654865 -0.129292652386806 1.08665972299343e-05 170.296463931767 88.5245062431011 1.92372113846202 0.0554408066089511 -509.744736616571 173.368935148674 -2.94023110991272 0.00356369888918709 TMEM159 other 0.0887257663824138 1 1 1.92372113846202 -2.94023110991272 1.20695122920742e-12 176.879436275429 32.9563040197818 5.36708959139525 1.73338840198018e-07 -168.984460008871 61.8492794351639 -2.73219771599791 0.00670948830405993 BRCA1 ts 1.4826188899584e-08 1 0.0020204375213481 5.36708959139525 -2.73219771599791 1.2735070396897e-25 383.206437279899 42.1347361729229 9.09478667926629 2.02247810642556e-17 -467.518665972718 118.376373627477 -3.94942547778975 9.97720485242113e-05 ERCC1 ts 1.95814442422688e-21 1 3.04059358520019e-13 9.09478667926629 -3.94942547778975 0.344812670848302 -1114.65047684416 762.57930889743 -1.4616846586826 0.144977735000867 -1048.13467235025 1982.05431878128 -0.528812284516361 0.597365340533672 LTF other 1 1 1 -1.4616846586826 -0.528812284516361 2.25740907330734e-16 260.63422631242 99.4811117003335 2.61993680868311 0.00929236162993623 -886.498785392671 169.250884850828 -5.23777932489985 3.27498936328826e-07 EXTL3 other 3.08926431682109e-12 0.00515352326207041 1 2.61993680868311 -5.23777932489985 8.746864578097e-16 1002.85471183597 118.203305416116 8.48415116908595 1.55487971314573e-15 109.405525547575 275.617586132825 0.396946824339616 0.691726168451943 ELOVL5 other 1.18012696887685e-11 1 2.28940488963578e-11 8.48415116908595 0.396946824339616 0.0357941743657851 -214.797328687574 138.27906103333 -1.55336120365903 0.121512562833087 -564.871995627521 217.531048610975 -2.59674193286181 0.00992895801460138 ALOX5 other 1 1 1 -1.55336120365903 -2.59674193286181 0.462750413921433 -57.9678856845539 91.7070931255957 -0.632098169387673 0.527851721659278 -302.292432754761 248.190847225121 -1.21798380614966 0.224281743794857 CALCOCO1 other 1 1 1 -0.632098169387673 -1.21798380614966 1.44062080405301e-18 244.055853759319 36.1440947570365 6.75230228893219 8.78141280918215e-11 -240.970403304889 72.6535912837824 -3.31670326334822 0.0010348480918486 UBR7 other 2.06138430851945e-14 1 1.17556773276521e-06 6.75230228893219 -3.31670326334822 4.64358025378252e-17 286.109356622997 40.8337976364157 7.00668008326131 1.94578731624014e-11 -138.128984635291 76.1590250125064 -1.813691609269 0.0708353097773128 MAP4K5 other 6.46200628116376e-13 1 2.65561052920454e-07 7.00668008326131 -1.813691609269 0.460298846993111 35.1877128548754 28.2842653036804 1.24407378014152 0.214543430211943 10.2855753680847 108.181503148235 0.0950770239713802 0.924323652799615 EHD3 other 1 1 1 1.24407378014152 0.0950770239713802 6.13888978458286e-48 1083.92762887876 60.7404844011836 17.8452252984936 9.67692887415101e-48 -125.235525622376 425.964467643633 -0.294004629811398 0.768977770895122 PSMC4 essential 9.77065698114207e-44 1 1.5404703074761e-43 17.8452252984936 -0.294004629811398 3.33750992416261e-14 258.706177386949 92.0354623307554 2.81094016192601 0.00530016210309414 -578.859228348329 139.053921670956 -4.16284000762012 4.22638738783146e-05 MAN2B2 other 4.31740283789676e-10 0.639621467274413 1 2.81094016192601 -4.16284000762012 0.000102014889882385 73.0440772194459 16.7845659494765 4.35185976445963 1.93897804902264e-05 -30.9474456060745 163.553705616712 -0.189218859269382 0.850068346361204 SLC7A14 other 0.755522274468942 1 0.19444071875599 4.35185976445963 -0.189218859269382 5.06042643441612e-06 697.529520813179 171.454541562674 4.06830588712169 6.2092890319484e-05 -414.602660657125 354.673160465048 -1.16897106088743 0.243438727616204 SLC25A39 other 0.0425068546299306 1 0.595160353712254 4.06830588712169 -1.16897106088743 0.000146401577016117 -506.025202181683 258.604778730709 -1.95675116548646 0.0514267412050413 -2190.37088583788 513.013182711561 -4.26961910464084 2.73028855931304e-05 MVP other 1 0.415440707185072 1 -1.95675116548646 -4.26961910464084 2.39742373608401e-09 163.627859445674 63.5283792585312 2.57566557427483 0.0105331391847304 -710.948135405639 161.818220726435 -4.39349865678937 1.59988535372768e-05 NUB1 other 2.53743328227132e-05 0.24510243619108 1 2.57566557427483 -4.39349865678937 5.07529366597591e-17 291.6643575282 37.201152931442 7.84019672900213 1.01447067658648e-13 -202.889999182607 88.8646144112917 -2.28313598755486 0.0231910869394044 PGM3 other 7.05313560760673e-13 1 1.45566397383395e-09 7.84019672900213 -2.28313598755486 0.000151097328500608 30.9004413928396 7.98620663262283 3.86922638172352 0.000136612819339024 -9.30966977276444 19.0771284514976 -0.488001629618088 0.625940386724356 RWDD2A other 1 1 1 3.86922638172352 -0.488001629618088 0.00217153753600106 65.2888270926455 71.2866413558343 0.91586341916082 0.36057120279556 -493.510373249112 163.969875030258 -3.00976245275569 0.00286652270602291 CLK1 other 1 1 1 0.91586341916082 -3.00976245275569 3.64168724436281e-07 72.1272422849531 16.9894480266667 4.24541410478681 2.99711690768353e-05 -83.3014632598317 37.774009185378 -2.20525872302898 0.0282726748449002 POLR3B essential 0.00336309817016905 1 0.295875381126518 4.24541410478681 -2.20525872302898 1.38926817454519e-23 233.690632256548 26.8163786141418 8.71447392726288 2.92209297393812e-16 -121.970297757267 50.2077864260097 -2.42931040062905 0.0157754278013218 ANGEL1 other 2.10751982078505e-19 1 4.34339899646161e-12 8.71447392726288 -2.42931040062905 8.8234654364645e-13 225.899953316336 48.7309113332894 4.63566034649588 5.51982545695763e-06 -288.576516321327 80.8609422848835 -3.5687998206184 0.000423517044420992 RNF14 other 1.08969798140337e-08 1 0.0578808897416577 4.63566034649588 -3.5687998206184 5.53705280325551e-24 464.296454942642 40.7093562571516 11.4051534494868 7.69684903744808e-25 279.014641921577 264.446763914461 1.05508813112883 0.292331717209533 DDX11 essential 8.4257332507139e-20 1 1.20240175663014e-20 11.4051534494868 1.05508813112883 1.64905006796375e-10 184.241176632693 26.3553610190791 6.99065273662225 2.11465871955745e-11 147.502387673072 112.90309867054 1.30645119053371 0.192502773753553 HEBP1 other 1.8563356615068e-06 1 2.8822798347568e-07 6.99065273662225 1.30645119053371 0.180139783086009 -36.3246235316301 25.8207897564244 -1.40679754083015 0.160628973125808 -89.5924222675817 55.0726777380581 -1.62680345222561 0.104936732076154 CD6 other 1 1 1 -1.40679754083015 -1.62680345222561 1.09106170614155e-43 944.558520352456 58.2097784377595 16.2268015048781 7.04444406021106e-42 328.884844392585 157.797998866881 2.08421429139943 0.0380737922709034 TACC3 essential 1.73446079425322e-39 1 1.11964393892995e-37 16.2268015048781 2.08421429139943 3.47706597523613e-14 162.046966928151 30.9243395957877 5.24011083328759 3.24559508754794e-07 -223.724276105173 56.8244818600199 -3.93711070971646 0.000105099117338413 UFL1 essential 4.49549859938279e-10 1 0.00372075020836496 5.24011083328759 -3.93711070971646 5.49250889151374e-09 190.090362901881 37.7435103360004 5.03637211297143 8.68863390965075e-07 -196.395069068602 87.8769812848087 -2.2348863854584 0.0262429759026597 POLA2 essential 5.68529595360587e-05 1 0.00967740044856901 5.03637211297143 -2.2348863854584 2.06753830858925e-13 150.170885080962 20.4547067360603 7.34162982724266 2.5110443865798e-12 -104.608579857033 77.7566569265512 -1.34533278553688 0.179650765012483 ZC3H3 other 2.61026711459393e-09 1 3.50667348585869e-08 7.34162982724266 -1.34533278553688 5.10052948030262e-07 844.606363768253 379.590496780765 2.22504612452419 0.0269015098340624 -3676.98858984366 883.815491388708 -4.16035770550496 4.26978590873672e-05 CAPN1 other 0.00465490852989977 0.646104003710041 1 2.22504612452419 -4.16035770550496 0.00805272196906221 32.0932214474318 12.6429572154444 2.53842680162101 0.011693237311118 -85.5130027786925 61.7858414527597 -1.38402262991068 0.167486086958876 ACPP other 1 1 1 2.53842680162101 -1.38402262991068 6.94048512072906e-20 1099.23727586851 107.367177044883 10.2381128583551 6.35949696517214e-21 370.650759556718 671.96803854956 0.551589864834593 0.581697726470783 MDH1 other 1.01303320822161e-15 1 9.7751827851661e-17 10.2381128583551 0.551589864834593 2.03733871598062e-23 274.248641811469 64.6726343689754 4.24056704180015 3.06533233576731e-05 -488.899442209597 94.9630023638559 -5.14831492307238 5.06976810622004e-07 SLC30A9 other 3.08677188858224e-19 0.00796308476443982 0.302149808336584 4.24056704180015 -5.14831492307238 0.68802606922633 18.2885841903854 32.9261388645527 0.555442721833212 0.579067642768127 -72.2719427125651 111.652091916208 -0.647295912438466 0.518009352401032 MTMR11 other 1 1 1 0.555442721833212 -0.647295912438466 1.33416712271438e-26 333.576932892792 31.3200244051782 10.6505961993325 2.21890438526253e-22 -6.29308008115004 50.5199706929216 -0.124566186298912 0.900958670551624 COX15 essential 2.06008745418328e-22 1 3.43353264575524e-18 10.6505961993325 -0.124566186298912 9.24328150220033e-16 807.23852858942 98.9825956544912 8.15535825517415 1.3062265382892e-14 41.7183944242986 212.448610578012 0.196369344618422 0.844468264290181 CCDC88C other 1.24639207639039e-11 1 1.9001677452493e-10 8.15535825517415 0.196369344618422 0.000907245362795115 38.4713771588396 14.6595713301965 2.6243180166936 0.00919193169191376 -72.0775343751836 39.3437485616084 -1.83199458644153 0.0680873662444984 YAF2 other 1 1 1 2.6243180166936 -1.83199458644153 1.00846764224687e-17 206.18118782032 74.9081760114732 2.75245238635554 0.00633996056833947 -750.423890104991 128.180369946246 -5.85443691900475 1.46716433803262e-08 ZMYND11 other 1.42173768203963e-13 0.00023295635359282 1 2.75245238635554 -5.85443691900475 0.422456677508434 -24.3771546770856 28.0986785169803 -0.867555200589032 0.386428758029759 -59.9033570625021 45.7860388936819 -1.30833237619881 0.191902842057103 DPEP1 other 1 1 1 -0.867555200589032 -1.30833237619881 2.01968551020292e-08 311.983377594841 66.364304470186 4.70107206103544 4.19466119434957e-06 -369.228209545343 189.655287099374 -1.94683847306549 0.0526267963841376 BID other 0.000201968551020292 1 0.0444046834033845 4.70107206103544 -1.94683847306549 1.31228070854522e-07 1069.78429772812 214.05028357937 4.99781770824633 1.04381558218217e-06 -60.0529998744905 352.026164193963 -0.170592433127788 0.864672012295481 MATR3 other 0.00124719158540138 1 0.0115623452038319 4.99781770824633 -0.170592433127788 0.0453271448711578 9.37722366327322 4.10339966418576 2.28523283878904 0.0230718288549139 -3.28870009176157 11.890030581254 -0.276593072598701 0.782303419107447 NPC1L1 other 1 1 1 2.28523283878904 -0.276593072598701 3.7510030216645e-09 362.205424243614 60.5012473943277 5.98674308122732 6.76988465377305e-09 -41.9065148261987 135.011782705022 -0.310391537587185 0.756501806236857 XYLT2 other 3.91829775643074e-05 1 8.46438678261245e-05 5.98674308122732 -0.310391537587185 6.47203394130691e-32 508.826769218116 47.7656653676581 10.6525632020744 2.310492690323e-22 -701.749888424303 138.406021453944 -5.07022657722892 7.37344196856951e-07 NUDCD3 essential 1.01753317625227e-27 0.0115645063835044 3.57479429046775e-18 10.6525632020744 -5.07022657722892 0.00389886986249643 26.9054029694344 8.52241515791613 3.15701622965915 0.00178256546330962 12.0495854820148 13.7272264597314 0.877787331429408 0.380872669750975 ISL1 other 1 1 1 3.15701622965915 0.877787331429408 0.709099212736845 -3.09966165709353 37.0684353389614 -0.0836199755600576 0.933420091777885 -75.7426862853105 93.3812220147149 -0.81111260541627 0.418010175940004 CHDH other 1 1 1 -0.0836199755600576 -0.81111260541627 0.0642765270274248 77.8998035124016 49.7679666111556 1.56525992152832 0.118693228918557 -110.75677742284 91.039516369303 -1.21657914980077 0.224826796020703 IL20RA other 1 1 1 1.56525992152832 -1.21657914980077 0.0369594401283811 -118.117022654002 166.726781132109 -0.708446608588993 0.479272426420777 -753.493628337429 300.787154554046 -2.50507249704388 0.0128255277998448 CLCA4 other 1 1 1 -0.708446608588993 -2.50507249704388 5.21693751796261e-11 138.702873160477 35.1682160476778 3.94398376569446 0.00010202587235836 -372.3380168185 84.4600590310232 -4.40845082385907 1.50022204964031e-05 GLT8D1 other 6.01252048945191e-07 0.229924031327874 0.956186475742551 3.94398376569446 -4.40845082385907 4.55791223305668e-07 608.273361671978 132.718004832495 4.58320152144907 6.99595188928518e-06 -1388.23428976266 617.17439832294 -2.24933875017327 0.0252939482122082 ATP2C1 other 0.00417550339670322 1 0.0727928794080123 4.58320152144907 -2.24933875017327 0.359731530158337 -22.5934488849497 56.8014163243178 -0.397762069099622 0.691118719591877 -179.048531678911 124.979074583317 -1.43262808014751 0.153116656340656 IGF1 other 1 1 1 -0.397762069099622 -1.43262808014751 5.17009549767756e-13 602.116506895103 84.5985738772866 7.11733637222415 1.01556204555469e-11 -59.1412307119779 186.244761424788 -0.317545740666971 0.751077725691342 RALBP1 other 6.43676889460856e-09 1 1.39721026227415e-07 7.11733637222415 -0.317545740666971 1.80838953319974e-14 117.570339047426 31.7394660035262 3.70423179250602 0.000257131151812512 -259.241516218064 59.4541247196225 -4.36036216899352 1.84844919033528e-05 RUFY3 other 2.3539806553661e-10 0.282590912218458 1 3.70423179250602 -4.36036216899352 0.0635054028208761 83.8898778422399 133.167094535642 0.629959511655388 0.529278582295342 -707.149414035128 356.658077405289 -1.98270965620542 0.0484604692272086 CNTN1 other 1 1 1 0.629959511655388 -1.98270965620542 0.377410982730556 -31.0304835814487 96.3676303508534 -0.3220011062685 0.747700101256716 -188.788975767272 143.534891729299 -1.31528281028226 0.189526634769367 SLC11A1 other 1 1 1 -0.3220011062685 -1.31528281028226 5.0815755453325e-05 311.856358989661 70.6223332010098 4.41583200178385 1.45894793637627e-05 -253.817312300845 447.336284982556 -0.567397103301698 0.570917624325036 WWTR1 other 0.38894379223975 1 0.147776836475552 4.41583200178385 -0.567397103301698 4.46263032280835e-09 330.594547325963 52.324746166396 6.31812997763337 1.11400530493563e-09 131.693044409671 156.851424166148 0.839603753104418 0.40188739668751 AGPS other 4.63979674662384e-05 1 1.43751244548893e-05 6.31812997763337 0.839603753104418 0.524744155583028 -12.467846949283 12.4748645909792 -0.999437457485415 0.318467851580504 22.1657206779576 46.6377876333317 0.475273845582587 0.63497182969981 ATP1A2 other 1 1 1 -0.999437457485415 0.475273845582587 1.09925111041799e-07 97.4620482017718 17.6730538824465 5.51472591268305 8.1705132803156e-08 146.240777264781 69.4808239063582 2.10476458169055 0.0362359725351296 TTC27 essential 0.00105033443600439 1 0.000969921631506264 5.51472591268305 2.10476458169055 0.0820307968356524 6.12173643121747 3.24749373112327 1.88506489559874 0.060483074707031 -2.60303678756358 7.40801602566141 -0.351381095632981 0.7255734980014 ZNF582 other 1 1 1 1.88506489559874 -0.351381095632981 0.311006366218171 -20.7336376935047 75.9049879353473 -0.273152506277516 0.784943265086397 -196.162519638603 135.934392285009 -1.44306761770279 0.150152053198188 VSIG2 other 1 1 1 -0.273152506277516 -1.44306761770279 0.612160681615615 146.649400625725 245.89365216087 0.596393600798542 0.551408329482483 712.532932878304 762.656425681037 0.934277754549863 0.350989289597889 MARCO other 1 1 1 0.596393600798542 0.934277754549863 0.548443885082566 -62.2450836760704 207.898220503283 -0.299401714576424 0.76486304619299 -706.610817676827 643.970231181867 -1.09727248786019 0.273496316374637 CYP24A1 other 1 1 1 -0.299401714576424 -1.09727248786019 0.00039529495064829 112.05181553216 40.5856907397675 2.76086998865261 0.00616748694495956 -102.619216630968 82.3778207271346 -1.2457141464191 0.213969606155509 PRDM11 other 1 1 1 2.76086998865261 -1.2457141464191 0.638903104119185 -15.6663750149139 157.927722199633 -0.0991996515666221 0.921054750089126 -280.513127169634 320.549961084157 -0.875099551473627 0.382312188609129 SYT13 other 1 1 1 -0.0991996515666221 -0.875099551473627 0.0469737910322042 124.487123374051 72.037247905172 1.72809382637608 0.0853253476469001 -288.782028129439 245.50077330606 -1.17629783499469 0.240702573739367 SNAI2 other 1 1 1 1.72809382637608 -1.17629783499469 0.0131393462731056 -4478.60232110924 5849.43900731955 -0.765646468918652 0.444550554577469 -28191.9654369078 9759.98011427261 -2.88852693415646 0.00418183827338346 CD74 other 1 1 1 -0.765646468918652 -2.88852693415646 0.427468235231934 -14.7560235658151 22.8118890419908 -0.646856713122402 0.518284562683504 -88.1525750704066 68.5139939672182 -1.2866360573372 0.19934401219761 HGF other 1 1 1 -0.646856713122402 -1.2866360573372 8.02418194167967e-14 176.286146811382 41.2112617827105 4.27762070816623 2.61541716633121e-05 -195.666529289059 57.4308802879307 -3.40699164470545 0.000755751034872531 ZRANB1 other 1.02589166124375e-09 1 0.259527845415046 4.27762070816623 -3.40699164470545 0.000145752801940304 58.5714172327939 45.8012620465626 1.27881666608333 0.202051609590658 -184.295713701984 65.503534512967 -2.81352319492777 0.00525764281926295 NCDN other 1 1 1 1.27881666608333 -2.81352319492777 0.0804283751889586 13.6605214176827 54.5955697533567 0.250213002252675 0.802663798544733 -198.626733344561 112.801928230503 -1.76084519529384 0.0796996128060771 ADGRA2 other 1 1 1 0.250213002252675 -1.76084519529384 2.10055128960549e-06 167.972385923556 32.5432626404185 5.16151031872679 4.74409067005046e-07 42.5190548352698 101.807709046993 0.417640817510623 0.676540446163052 ZFP64 other 0.0182138802321692 1 0.00537220827476514 5.16151031872679 0.417640817510623 5.22941755961192e-22 175.687406838369 20.0183585846976 8.77631430644206 1.90566355208979e-16 -36.9856773520138 35.8194386753602 -1.03255882056733 0.30272761658252 MNAT1 essential 7.82791514498308e-18 1 2.83943869261378e-12 8.77631430644206 -1.03255882056733 0.020914332606195 129.517537659152 47.4054943787917 2.73212080912493 0.00670631496201019 66.1253661846861 91.2597462030574 0.724584156058838 0.469332291452886 SAMD4A other 1 1 1 2.73212080912493 0.724584156058838 0.185483724449694 39.8494486353181 90.1876140033934 0.441850569789092 0.65894971895807 -158.32955031687 132.946388529758 -1.19092780231056 0.234723993571964 RUNX3 other 1 1 1 0.441850569789092 -1.19092780231056 9.31959458312439e-16 202.275829111101 29.1896641143844 6.92970732100413 3.11387928652911e-11 -61.468705927733 52.0325157288759 -1.18135179640412 0.238506364355222 MRE11 other 1.25646774169683e-11 1 4.22304308839078e-07 6.92970732100413 -1.18135179640412 0.618499865404006 34.3160774154628 63.188598095447 0.543073884368 0.587533707729958 -100.5092912865 171.723737682219 -0.585296433929807 0.558844602500633 PLEKHB1 other 1 1 1 0.543073884368 -0.585296433929807 0.113981938063156 -270.130189901843 298.513328141209 -0.904918355183325 0.366327511206229 -1123.37118573082 537.301338009682 -2.09076565841453 0.0374981866316544 SERPINB1 other 1 1 1 -0.904918355183325 -2.09076565841453 0.000151125932442042 248.323964916997 58.2797835878876 4.26089373757742 2.8154195328944e-05 -0.292729391725434 229.124372488481 -0.00127760040778792 0.998981566067024 SPAST other 1 1 0.278642071170559 4.26089373757742 -0.00127760040778792 0.00366522134150933 95.7790108443161 28.3070968653608 3.38356883787402 0.00082038336690794 82.0770404436957 53.5528813726194 1.53263537535181 0.126523716019623 NRXN3 other 1 1 1 3.38356883787402 1.53263537535181 0.00205212856267246 -24.6068747007045 49.060350760663 -0.501563366734722 0.616380403574939 -219.477509494653 72.7893134180646 -3.01524357338126 0.00281036072312992 OSBPL5 other 1 1 1 -0.501563366734722 -3.01524357338126 9.60521810592052e-21 359.807932216901 47.861994500826 7.51761258529858 8.40186840798982e-13 -206.282791785416 85.2514814837399 -2.41969744331962 0.0161992136053022 AQR essential 1.41744203589069e-16 1 1.1853355949992e-08 7.51761258529858 -2.41969744331962 0.395138710328177 197.482035886914 374.213774693368 0.527725191432974 0.59813000298595 881.688230844836 649.712924562881 1.35704277614305 0.175918011942095 CPS1 other 1 1 1 0.527725191432974 1.35704277614305 0.532017592874857 -16.1373471217671 15.4899149700859 -1.04179701134135 0.298434297524527 -5.74706673522634 24.5404289327989 -0.234187705152343 0.815016084805621 C8B other 1 1 1 -1.04179701134135 -0.234187705152343 3.70994319933356e-27 488.684295162411 47.6221317925942 10.2617055719124 4.47116285911623e-21 -569.484839819151 147.243368354061 -3.86764338649039 0.00013778624615063 RTFDC1 essential 5.74484704416802e-23 1 6.87776372782422e-17 10.2617055719124 -3.86764338649039 0.089019538020447 -125.265285667466 107.739183044313 -1.16267157526101 0.245978110310075 -526.472416767785 240.436964796678 -2.18964840623816 0.0293961927900184 NLRP2 other 1 1 1 -1.16267157526101 -2.18964840623816 0.00470697894888507 77.696120552114 29.7588561575333 2.61085708875425 0.00953444827867102 -159.858641516755 115.63049734922 -1.38249549367552 0.167957852633318 SLC45A4 other 1 1 1 2.61085708875425 -1.38249549367552 2.1687437335251e-08 291.682243489806 100.575283250319 2.90013842430697 0.00403567449889347 -884.576984849601 209.863376517723 -4.21501359373629 3.40591130401466e-05 RNF10 other 0.000216397249731135 0.516676744819024 1 2.90013842430697 -4.21501359373629 6.03934055821808e-13 89.9284015489402 12.6885172011958 7.08738461106119 1.20109384764411e-11 0.730504285454022 28.0784694908139 0.0260165279198359 0.979263445046016 ZNF839 other 7.5050885116976e-09 1 1.6489817434306e-07 7.08738461106119 0.0260165279198359 7.03589705621916e-10 134.962705788063 34.8505241377237 3.87261624114208 0.00013493181271611 -115.42668214057 49.0219116132982 -2.35459365703841 0.0192539453708543 ZDHHC6 other 7.6698313809845e-06 1 1 3.87261624114208 -2.35459365703841 0.838976467609203 10.4433933971987 25.1206387306131 0.415729612180278 0.677934460785513 -7.36918453376589 45.4920795940533 -0.161988297732803 0.871434894540798 GRAMD1B other 1 1 1 0.415729612180278 -0.161988297732803 5.68448036514055e-08 240.174591390916 192.283515285493 1.24906490831685 0.212715202305644 -1069.30791417688 308.872704295866 -3.46196960529279 0.000622578907273878 RNH1 other 0.000552588336295313 1 1 1.24906490831685 -3.46196960529279 4.45329373677698e-25 695.157736847125 69.5160197361452 9.99996460507468 3.18208963776495e-20 -295.174220819338 136.194105647026 -2.16730540148589 0.0310890588636279 NDUFS1 other 6.82289133411602e-21 1 4.8749613250559e-16 9.99996460507468 -2.16730540148589 8.21159712029419e-09 249.133615629486 63.5825501378324 3.91827026581069 0.000115393375799166 -677.682084264404 206.446806832139 -3.28259901261357 0.00117658259216275 RB1CC1 other 8.41113893031734e-05 1 1 3.91827026581069 -3.28259901261357 3.07565955920637e-22 402.442416807238 57.902561936004 6.95033869575636 2.75115477958227e-11 -505.757938605591 111.918984531648 -4.51896468433893 9.31636647413575e-06 ERP44 other 4.61471960263323e-18 0.14342546186932 3.73744376806252e-07 6.95033869575636 -4.51896468433893 0.000574746937107858 225.305281769893 75.3810666638941 2.98888423500923 0.00305691119158028 -248.329465831794 178.174956758065 -1.39373944773276 0.164538152065286 ALAS1 other 1 1 1 2.98888423500923 -1.39373944773276 0.439094188056372 254.486090902655 276.231631025333 0.921277878127276 0.357730858293341 604.529857664748 488.796136383815 1.23677298707217 0.217250040082005 BIRC3 og 1 1 1 0.921277878127276 1.23677298707217 1.40411695489703e-08 120.966172976269 53.655693526245 2.2544890397717 0.0249611273998583 -332.460027464874 85.2342902209257 -3.90054315702218 0.000121008800270423 AKAP11 other 0.000141661359579562 1 1 2.2544890397717 -3.90054315702218 0.000417670348447728 23.4322455561342 6.14111984639793 3.81563072244525 0.000169653673440865 -15.9362219768222 16.8529462551447 -0.945604509476046 0.345224926590432 GLRX2 other 1 1 1 3.81563072244525 -0.945604509476046 1.33404903702687e-07 252.697130957171 46.6154151718725 5.42089199517947 1.30845570207197e-07 83.0703192641159 83.4627483917133 0.995298152347492 0.320475870139803 SNAPC1 essential 0.00126654615575331 1 0.00153756629550477 5.42089199517947 0.995298152347492 1.03168271146484e-11 352.187859527102 48.2543673839552 7.29856961391242 3.33458095225798e-12 62.8945552337235 199.220409837835 0.315703372384985 0.752474297043157 DERA other 1.22326619098386e-07 1 4.64340397601923e-08 7.29856961391242 0.315703372384985 1.09520037127733e-21 1132.88047567751 110.482042246834 10.2539784080609 4.9786351189576e-21 -302.676429800776 459.269546770248 -0.659038753884962 0.510436727700121 STRAP essential 1.63349135376013e-17 1 7.6556472224211e-17 10.2539784080609 -0.659038753884962 0.995271065961204 1.95244360372424 138.236361151976 0.0141239510896684 0.988741408291183 -17.3074458854014 222.978654925291 -0.0776192945069123 0.938187751275656 ABCC2 other 1 1 1 0.0141239510896684 -0.0776192945069123 0.00246164890460736 75.1158474164665 30.578494161044 2.4564926912641 0.0146552016408404 -79.4694397050945 58.803352117474 -1.35144403921625 0.177676130623091 DEF6 other 1 1 1 2.4564926912641 -1.35144403921625 0.00413551613992869 139.959851701859 41.8059771420558 3.34784309014661 0.000933497363045294 16.403767492823 141.905022411678 0.115596807033611 0.908060304825939 PLEKHO1 other 1 1 1 3.34784309014661 0.115596807033611 0.038026289344002 1359.70248378387 537.574333126265 2.52932924806234 0.011991343590988 1507.01825995289 866.928319003277 1.73834240607751 0.0832779622408936 GCLM other 1 1 1 2.52932924806234 1.73834240607751 9.83618940606662e-18 246.832245811956 28.6526434497731 8.61464130681843 5.97026421158643e-16 -51.6086907225262 64.2708651683041 -0.802987334733711 0.422688341670156 UBR2 other 1.38680434436133e-13 1 8.83897616525371e-12 8.61464130681843 -0.802987334733711 0.0056632326340374 364.563569099073 246.61764469167 1.47825420016018 0.140492554902795 -1010.6354013195 509.9433097455 -1.98185833994741 0.0484978996828382 EHD2 other 1 1 1 1.47825420016018 -1.98185833994741 1.18627341957122e-10 228.228685893191 41.0342205134042 5.56191108391197 6.39603291085644e-08 -28.6681150588627 63.3397123816284 -0.452608860711813 0.651192531937855 DEPDC1 other 1.34452229374202e-06 1 0.000763558408898042 5.56191108391197 -0.452608860711813 1.1318059099011e-08 103.610819530111 20.7626422358404 4.99025212461919 1.07973871419233e-06 -79.2222671035506 37.9502046493127 -2.0875320129528 0.0377741017198825 CCDC28A other 0.00011490093597316 1 0.0119462291338239 4.99025212461919 -2.0875320129528 3.31219003349638e-07 220.876372369625 41.5442952070036 5.3166474787708 2.20623510091549e-07 -29.774045792573 96.7926659524608 -0.30760642347837 0.758617232748323 RRAGD other 0.00306851119389676 1 0.00255548211739041 5.3166474787708 -0.30760642347837 1.6908664506526e-09 167.072780629175 29.9488940060886 5.57859601076449 5.92376975813631e-08 -70.3523565118392 53.6706649227844 -1.31081581741264 0.191042119202755 HSF2 other 1.80432358949139e-05 1 0.000708897526956172 5.57859601076449 -1.31081581741264 1.60483477331449e-20 231.377985074884 24.2499487786094 9.54138036278986 9.34852502776682e-19 -190.619937465602 102.926408861628 -1.85200221764141 0.0651292957777486 PHF20 other 2.36039098459096e-16 1 1.42078883372e-14 9.54138036278986 -1.85200221764141 0.883385758143312 -21.7596143964739 49.9994467552853 -0.435197103339424 0.663764478797447 11.2285888418192 133.825249067848 0.083904860405875 0.933193793565335 HSD17B6 other 1 1 1 -0.435197103339424 0.083904860405875 0.0594951665924843 0.18512307486431 36.2216268072977 0.00511084374672572 0.995925942550521 -162.800338288633 76.5630908035883 -2.1263553571299 0.034384247546688 NR1H3 other 1 1 1 0.00511084374672572 -2.1263553571299 0.291263130323577 -49.9618956411833 324.215895664351 -0.154100697434363 0.877648521127728 -1010.09261312006 684.18179174408 -1.47635120564256 0.141045939874221 TYMP other 1 1 1 -0.154100697434363 -1.47635120564256 3.24567392607682e-17 419.194615690515 55.5096424214518 7.55174411875722 7.09009673344856e-13 -199.519198024069 117.140112865719 -1.70325256774154 0.0897021354932814 NCAPH2 essential 4.53323277255149e-13 1 1.00211427230562e-08 7.55174411875722 -1.70325256774154 5.6254689939623e-14 325.280896977789 44.8707420888318 7.24928721557182 4.34940613198122e-12 -285.617475213316 153.334505686942 -1.86270842256767 0.0635812595157702 TOMM34 other 7.22985275104035e-10 1 6.03697571118993e-08 7.24928721557182 -1.86270842256767 1.48162014133825e-14 412.754759510043 79.2290624039509 5.20963831940362 3.77798236501487e-07 -571.566152363638 138.230163463528 -4.1348873360368 4.75509422879625e-05 SEC63 essential 1.93351428444642e-10 0.718399636086537 0.00431105567671847 5.20963831940362 -4.1348873360368 8.89514566145681e-18 340.729687920366 92.7066945730593 3.6753514887951 0.000287051054453455 -700.438947179624 131.925584270167 -5.30934883521315 2.3173336073567e-07 KPNA6 other 1.2553719072014e-13 0.00365258123191562 1 3.6753514887951 -5.30934883521315 0.492121232697502 -327.413259948174 1684.97556792814 -0.194313357522901 0.846075572862228 -3096.54634673356 2861.69544519926 -1.08206704942285 0.280181098267675 VIM other 1 1 1 -0.194313357522901 -1.08206704942285 0.0774074173089098 8.35502469872342 79.6930146622109 0.104840113454577 0.91658109977394 -197.211302760801 114.601185569125 -1.72084871357502 0.0864324239087644 FAS ts 1 1 1 0.104840113454577 -1.72084871357502 0.293565442836613 131.91442566008 108.981605862596 1.21042835271117 0.227169219323236 -120.0885353218 203.577006850484 -0.589892430288056 0.555754279126667 RNASET2 other 1 1 1 1.21042835271117 -0.589892430288056 1.33210365085774e-06 3956.4040399042 932.615834997275 4.24226556255692 3.05413138356265e-05 -2359.40882999148 2150.01828825109 -1.09739012123042 0.273459584304 CD44 other 0.011751818407867 1 0.301137354419277 4.24226556255692 -1.09739012123042 1.20604697864867e-06 148.424380033348 28.3305537896769 5.23902148666897 3.26302160152937e-07 29.7799198211942 94.7393903184146 0.314335143187066 0.753510160133213 KCNG1 other 0.0106723097140621 1 0.00373942275535265 5.23902148666897 0.314335143187066 0.000165259779709772 120.609142838645 36.1431487914638 3.33698492996631 0.000966345432866221 -98.3658741561736 66.9134529884731 -1.47004630254425 0.142717849442648 AGPAT4 other 1 1 1 3.33698492996631 -1.47004630254425 0.570005814147332 -72.3004555096434 68.3868767408034 -1.05722704348194 0.291349485724636 6.37501379403337 241.254713520284 0.0264244113659457 0.978938271101501 SLAMF7 other 1 1 1 -1.05722704348194 0.0264244113659457 0.778916523133077 39.9230132091232 71.5034035393823 0.558337243165419 0.577075115615966 -23.7477022308016 124.714070540979 -0.190417184907765 0.849124794857016 BTN3A1 other 1 1 1 0.558337243165419 -0.190417184907765 4.59840136391261e-10 183.998727779934 34.2654403876748 5.36980484412853 1.69632955603006e-07 -22.7268145599143 52.5982610332439 -0.432083002621516 0.666024679130387 MIPEP essential 5.06238006153139e-06 1 0.00197910769302028 5.36980484412853 -0.432083002621516 1.40330842736622e-08 174.449504236052 51.660672164301 3.37683380659924 0.000840309562757735 -255.257742513966 92.6233948256004 -2.75586684114297 0.00624928489981736 PRKCH other 0.000141593820321252 1 1 3.37683380659924 -2.75586684114297 0.0115872166562381 470.948605831796 240.858796252466 1.95528921160161 0.0515804269086914 -708.169585543424 440.598035588656 -1.60729174517831 0.109159138754109 IFNGR1 other 1 1 1 1.95528921160161 -1.60729174517831 7.48410524579488e-06 108.976247057711 30.8216917050495 3.53569973058478 0.000477610380218664 -76.7317747494736 51.6332449637657 -1.48609243527733 0.138408575345163 B4GALT7 other 0.0619234868037068 1 1 3.53569973058478 -1.48609243527733 0.0647599768271509 36.8204454060323 16.0318247455758 2.29670957550814 0.0223954275765445 -18.8652167631459 52.2577861077886 -0.361002984784582 0.718377438195299 SH2D2A other 1 1 1 2.29670957550814 -0.361002984784582 0.00597750998196513 185.931974142916 57.5541139707387 3.23055923052601 0.00139398794341651 -14.4024049616382 340.301255737829 -0.0423225148858515 0.966273955701275 VRK2 other 1 1 1 3.23055923052601 -0.0423225148858515 2.85605150568211e-12 242.538032214666 50.0445014116383 4.84644716948388 2.11496522815901e-06 -492.846957604627 115.332184369187 -4.27328208773874 2.66662596496381e-05 VEZT essential 3.45639353217648e-08 0.405887138127142 0.0228987285252776 4.84644716948388 -4.27328208773874 0.0327607387575952 -8.05522313068113 20.0202083894932 -0.402354609600797 0.687741420669086 -139.554527088041 54.4080274919632 -2.56496207491908 0.0108595792986929 POU2F2 other 1 1 1 -0.402354609600797 -2.56496207491908 3.96839423559698e-23 398.669804882118 35.9441005083893 11.0913835439857 9.5241228567129e-24 -77.7575256204445 208.374996434684 -0.373161497064826 0.709325449602325 BRD9 other 5.99743420825771e-19 1 1.48252496387593e-19 11.0913835439857 -0.373161497064826 5.34783288164907e-10 418.741140091827 92.43620751643 4.53005539000935 8.82287067968248e-06 -517.624336878357 183.165338633829 -2.82599503126055 0.00506160715663906 SNX1 other 5.86496832130453e-06 1 0.0909990881902451 4.53005539000935 -2.82599503126055 0.0930334789845416 133.434578417473 65.0531950608433 2.05116102741263 0.0412126136250701 -10.5564494897764 118.866304311221 -0.0888094363743073 0.929298952584791 TBPL1 other 1 1 1 2.05116102741263 -0.0888094363743073 1.82852259069939e-11 629.79214035464 86.058655815776 7.31817310396787 2.85918037998087e-12 289.178830616331 539.92603103661 0.535589717838077 0.592681400829834 ARNTL2 other 2.1477826350355e-07 1 3.98769887595931e-08 7.31817310396787 0.535589717838077 1.78944726725898e-10 452.530549014244 81.2089601110717 5.57242142240592 6.07764416722607e-08 -353.057291955837 148.553878263308 -2.37662790149478 0.0181691557132824 BCLAF1 essential 2.01026506003873e-06 1 0.000726703913075221 5.57242142240592 -2.37662790149478 2.57375093934929e-18 497.030372854007 74.363489918048 6.68379568255548 1.32167434097655e-10 -404.514231971695 136.50491789719 -2.96336746106362 0.00331329363755144 SLC39A9 other 3.66759508857274e-14 1 1.76099889191715e-06 6.68379568255548 -2.96336746106362 0.325882475349458 9.57883513919155 13.3842621193008 0.715678985797686 0.475127351639039 -29.8254809505369 34.1293544117859 -0.873895257164233 0.383352784613438 ANK1 other 1 1 1 0.715678985797686 -0.873895257164233 0.264266466594242 3.0674825107199 5.06395548771746 0.605748316342832 0.545187017651993 12.3095786838568 7.86212771252689 1.56568032649021 0.118586111468119 IBSP other 1 1 1 0.605748316342832 1.56568032649021 5.59901975138392e-08 46.2344783171902 10.6918321948357 4.32428020517586 2.14739510470917e-05 -52.2386684134605 20.8518017943466 -2.5052352275679 0.0128197636908667 TFB1M other 0.000544616651217114 1 0.21448518391546 4.32428020517586 -2.5052352275679 2.7383547143979e-27 401.894345110788 35.3668221498025 11.3635978773692 9.26465810522538e-25 -187.231243049019 108.860367197175 -1.71992110507851 0.0865800700634549 RABEP1 other 4.24335446543099e-23 1 1.44686165629305e-20 11.3635978773692 -1.71992110507851 1.13011819621325e-10 414.699367088609 76.6513752718237 5.41020126015989 1.39616440131772e-07 -272.589181388232 163.009715502772 -1.67222659427067 0.0956466623235278 NUP160 essential 1.28200608178431e-06 1 0.00163728199342529 5.41020126015989 -1.67222659427067 7.40385128914818e-07 212.019174385948 51.3377249933884 4.12989033723744 4.83829628457789e-05 -132.179405186525 94.5633828780642 -1.39778634354659 0.163320331459478 BAK1 other 0.00666050461971771 1 0.467572952941607 4.12989033723744 -1.39778634354659 0.000224935600950633 -66.621009011014 36.9742527877237 -1.80182164582198 0.0726888715849959 -241.596979641786 58.4470610440396 -4.13360356066053 4.77022637644537e-05 IKZF2 other 1 0.720638098689602 1 -1.80182164582198 -4.13360356066053 0.123724100757636 1112.29072640405 581.278410235229 1.91352492509387 0.0567304942050335 76.77407301168 1202.44030277183 0.0638485526763389 0.949137714404543 GRN other 1 1 1 1.91352492509387 0.0638485526763389 0.000129954588325336 11.1767629213179 34.9881477402695 0.319444258789786 0.749634858983538 -209.578159271428 57.6529279548945 -3.63516939565315 0.000332132063302583 FAM13B other 0.949448222304908 1 1 0.319444258789786 -3.63516939565315 0.263700344200455 -6.07594825282036 58.3910647513619 -0.104056130483194 0.917201771079542 -360.945859014597 222.057323821136 -1.62546252833946 0.105226376714087 ARHGAP31 other 1 1 1 -0.104056130483194 -1.62546252833946 4.35906484286252e-14 90.9220314029408 11.4463275600581 7.94333649162838 5.51677739125206e-14 1.35250298535171 28.9700064221609 0.0466863198317104 0.962798133704128 CENPQ other 5.62188592783979e-10 1 7.94471112114209e-10 7.94333649162838 0.0466863198317104 5.6898617052147e-20 531.930233380168 140.171678256461 3.79484814619211 0.000182137876233897 -1050.6348329401 208.987615672316 -5.02725881416555 9.03681758536945e-07 SARS essential 8.31288795131868e-16 0.0141579821109983 1 3.79484814619211 -5.02725881416555 5.66522050515183e-28 276.571584485993 45.6101027961679 6.0638228710423 4.42901924992849e-09 -540.48136236524 85.7939642954216 -6.29975974188762 1.19444582003787e-09 RANBP3 other 8.80545223115748e-24 1.9021549684103e-05 5.58100715683489e-05 6.0638228710423 -6.29975974188762 1.50785978132584e-09 68.9543323092335 18.8897916730168 3.65034900875755 0.000313972325504675 -103.302147128024 35.0219814622443 -2.94963742241111 0.00345821473513418 ARID4A other 1.61401310993118e-05 1 1 3.65034900875755 -2.94963742241111 6.41583589396231e-09 412.145435214594 82.7293458942035 4.98185294178026 1.12131058156283e-06 -205.271942533881 183.701725425813 -1.11741978502417 0.264800898118517 PNPLA6 other 6.61472680667514e-05 1 0.0123848753733615 4.98185294178026 -1.11741978502417 6.84287531654676e-07 60.928154355568 15.9900389492405 3.81038186016814 0.000173386886094524 -23.5340598647875 24.1193968283596 -0.975731691478959 0.330107888558879 IFT88 other 0.00617501068565179 1 1 3.81038186016814 -0.975731691478959 1.59128650663012e-30 178.728627971873 19.7899270718387 9.03129290588471 3.2157434693826e-17 -154.383044774749 38.7205612033238 -3.98710762388166 8.60005913416239e-05 ALG1 essential 2.49577375699868e-26 1 4.82297205538003e-13 9.03129290588471 -3.98710762388166 9.74773822360178e-08 62.576408838271 20.3798266661774 3.07050741222072 0.00235324887314304 -165.09302865737 42.2353710540095 -3.90888074467852 0.000117123511167502 ZCCHC8 other 0.000934223231349994 1 1 3.07050741222072 -3.90888074467852 1.86116119845749e-20 430.2647648567 52.8378624325347 8.14311452144904 1.38482538933674e-14 -332.597000809066 133.298215496918 -2.4951346840555 0.0131819367782022 ABCF2 other 2.73609307785236e-16 1 2.01367459863455e-10 8.14311452144904 -2.4951346840555 0.320381814362439 1.01665089959118 13.2787472782086 0.076562259849585 0.939028484451636 -24.9858725557418 20.851468680414 -1.19827878499567 0.231859253853951 LRRC7 other 1 1 1 0.076562259849585 -1.19827878499567 3.61044515359957e-06 312.666489457857 72.602637927425 4.30654447804506 2.31769761793496e-05 -30.9179528452712 134.762467086483 -0.229425547882184 0.818710603467477 FUT8 other 0.0306707315798284 1 0.23093539065104 4.30654447804506 -0.229425547882184 1.19481751569248e-13 436.854209043056 89.992081490066 4.85436275958657 2.04620333386307e-06 -512.436324136041 171.443942197849 -2.98894389365289 0.00305730722058278 UBA6 other 1.51944943470613e-09 1 0.0221972137657466 4.85436275958657 -2.98894389365289 1.2299327278066e-05 365.751381900066 79.2657877339883 4.61424017039367 6.1026269964105e-06 78.3498813517786 199.498442406177 0.392734301114286 0.69482561067495 GAB2 other 0.0999812314433981 1 0.0637480416045041 4.61424017039367 0.392734301114286 4.40153321196344e-07 125.276289215026 38.5367744104373 3.25082446913607 0.00129617511598116 -208.359768412549 74.3599766846437 -2.80204187389933 0.00544426766657128 PIAS1 other 0.00403752641533406 1 1 3.25082446913607 -2.80204187389933 5.62333776425689e-07 197.155993941982 37.4901109240121 5.25887998415352 2.9445637923748e-07 27.9762080437011 97.7974977788124 0.286062615906336 0.775048712335569 SLC4A7 other 0.00511161402770952 1 0.00338359825381788 5.25887998415352 0.286062615906336 7.95334060068902e-05 165.003900411218 42.1535640360938 3.91435230173975 0.000114734275434328 24.9194220256386 77.8205857133698 0.320216325760156 0.749051102069595 APBA2 other 0.596341478239662 1 1 3.91435230173975 0.320216325760156 1.21034952440622e-07 313.051140682118 76.9587409459756 4.06777887520115 6.2165959329599e-05 -230.116879199892 188.357627601535 -1.22170194077141 0.222874251833703 MAP2K3 other 0.00115297895694937 1 0.595736388255547 4.06777887520115 -1.22170194077141 0.188162843434244 27.1420003603226 16.7276353084419 1.62258441554049 0.106078570212135 -17.6493111197504 56.9146385972979 -0.310101435320163 0.756770855015651 EFCAB1 other 1 1 1 1.62258441554049 -0.310101435320163 0.664315422225563 -749.232177109978 1411.9711657199 -0.530628525071884 0.59611894360846 -4599.61575554136 5810.91031543746 -0.791548226673172 0.429329403885107 TMSB10 other 1 1 1 -0.530628525071884 -0.791548226673172 4.0705144256595e-16 56.1079820521901 6.96118419806149 8.06012029789625 2.45392666656141e-14 -80.0471720392017 32.3713777529742 -2.47277618673018 0.0140207037065543 ASTE1 other 5.53712077322462e-12 1 3.55475816918086e-10 8.06012029789625 -2.47277618673018 0.00052169627184528 276.11299045485 88.4097256502318 3.12310651824905 0.00198348590457155 -514.757445572205 341.386654649273 -1.50784290645762 0.13275959897844 RNF19A other 1 1 1 3.12310651824905 -1.50784290645762 2.78911133158677e-10 114.019029142131 20.5084647158014 5.5596082262697 6.4337713763275e-08 -71.9888869154151 36.1862575634857 -1.98939851099873 0.0476549813035693 PEX3 other 3.10511764545555e-06 1 0.000767999289192214 5.5596082262697 -1.98939851099873 5.88793333198801e-07 266.425647951416 109.806197940366 2.42632613594461 0.0159053315214426 -501.158931966177 187.622263691287 -2.6711058810738 0.00801755727445458 GABARAPL2 other 0.00534035553211313 1 1 2.42632613594461 -2.6711058810738 0.556078772902909 -15.7760311964295 14.8894892160558 -1.05954146361298 0.290300181475084 -15.2160528678569 48.2214209745345 -0.315545509865676 0.752591262156436 MYOC other 1 1 1 -1.05954146361298 -0.315545509865676 0.00122081113249449 82.4164644602508 56.5343455815736 1.45781230175083 0.14608988467684 -461.102653982867 167.817727362457 -2.74763972334679 0.00641937293452803 SH3YL1 other 1 1 1 1.45781230175083 -2.74763972334679 3.86065358530598e-07 263.761433718843 47.5014665467795 5.55270085101668 6.66645182397587e-08 200.730519349074 219.490046621956 0.914531307630578 0.36124476097052 FAM136A other 0.00355720621350093 1 0.000795041044527362 5.55270085101668 0.914531307630578 3.56593103177654e-07 661.51995934687 250.024069179518 2.64582510602968 0.00863081171823023 -910.562803899418 391.673702460541 -2.32479943937812 0.0208300045171469 VCL other 0.00329634664577423 1 1 2.64582510602968 -2.32479943937812 2.92171692962459e-11 166.891511966319 24.7082671787486 6.75448062621976 8.82753207572388e-11 56.6334392252 44.5701274940876 1.27065912550312 0.204947753702511 DEPDC1B other 3.40175502116191e-07 1 1.1816534436564e-06 6.75448062621976 1.27065912550312 0.610618715574869 -13.9001722278559 41.4358892151871 -0.335462143835475 0.737534140601126 -81.5709196696411 82.2055283014602 -0.992280219531078 0.321939519186885 DAPK2 other 1 1 1 -0.335462143835475 -0.992280219531078 1.48052955129489e-07 110.648036779324 27.3947351656178 4.03902560511681 7.05531718444025e-05 -204.391072316103 83.2108623869728 -2.45630277650027 0.0146868386354557 NSMAF other 0.00140161732621087 1 0.672724493536378 4.03902560511681 -2.45630277650027 7.03187724512444e-10 396.812715314751 61.4460794581425 6.45790128213246 4.89112060369325e-10 -197.163097159652 166.895406895572 -1.18135723940575 0.23849651419841 ADSS other 7.66615257263466e-06 1 6.38731439636302e-06 6.45790128213246 -1.18135723940575 0.0621789322813363 -8.3757258305896 5.8378629956047 -1.43472463072457 0.152527143652243 -23.5397121403381 9.94584717178486 -2.36678804065252 0.0186516997698739 STAP1 other 1 1 1 -1.43472463072457 -2.36678804065252 0.428411587602669 -448.294397928863 343.983372863612 -1.30324438125272 0.193589403633705 -253.62062604807 772.052939056898 -0.328501600366784 0.742784266098642 TIMP2 other 1 1 1 -1.30324438125272 -0.328501600366784 3.72357875205541e-24 358.178015191426 63.0439690844264 5.68140014648769 3.44264316728306e-08 -433.396413113193 101.479774970682 -4.27076639890466 2.69806187232454e-05 RFC1 other 5.67324458663163e-20 0.410618036349072 0.000416422117514559 5.68140014648769 -4.27076639890466 1.88247331686079e-18 295.49772152428 34.0742919592327 8.67216028664132 4.14200189667218e-16 -263.165687688567 124.424955617985 -2.11505550780785 0.0353481817291475 TBC1D23 other 2.68986612246238e-14 1 6.14590241428219e-12 8.67216028664132 -2.11505550780785 3.19994746647471e-08 151.031008150127 70.322812554432 2.14768156539848 0.0326291917719078 -372.948685021575 102.773850765109 -3.62882856140083 0.000340440359319383 CUL3 essential 0.000316186809162366 1 1 2.14768156539848 -3.62882856140083 0.000303794721884331 28.0099306790015 12.9549461174161 2.16210321719101 0.0315332730000248 -30.4887850064891 21.5007217468841 -1.41803542064385 0.157391793870449 MYOM2 other 1 1 1 2.16210321719101 -1.41803542064385 0.480556245902418 3.43304766574923 2.99609033091559 1.1458425102624 0.25287863995503 0.95135239879861 6.58139413978816 0.144551804464522 0.88517299231349 CYP46A1 other 1 1 1 1.1458425102624 0.144551804464522 6.54063224717503e-24 281.824955324258 36.8021391754134 7.65784168091342 3.3841068714637e-13 -213.271246164163 63.5042221439221 -3.35837900164839 0.000896914740313755 ZZZ3 other 9.94830164795322e-20 1 4.82032182771289e-09 7.65784168091342 -3.35837900164839 0.000386963420037683 28.7239735874721 9.74930009251623 2.94626007148157 0.00349605326620629 -15.4371690901108 17.625735128203 -0.875831219397466 0.381897425792439 USP2 other 1 1 1 2.94626007148157 -0.875831219397466 0.000594156432598739 98.7831912039963 30.3486484486663 3.25494531893519 0.00127988785786169 -31.5817342592168 56.7896737010897 -0.556117550973194 0.578594498129556 TUBG2 other 1 1 1 3.25494531893519 -0.556117550973194 4.94025383612313e-11 96.6947088067043 15.7992877411881 6.12019417524911 3.24882232621007e-09 -9.62081648724207 25.6042139601365 -0.375751292432598 0.707394678976225 RPL26L1 other 5.70105292688609e-07 1 4.11918182740175e-05 6.12019417524911 -0.375751292432598 0.593328053641273 28.6573507164048 47.0055059985632 0.609659445369672 0.542596364444893 -36.3675361661184 77.2095363407541 -0.471023890178735 0.638001210523381 FLT4 other 1 1 1 0.609659445369672 -0.471023890178735 3.71031692981995e-29 765.86187993063 59.1145167291073 12.9555635790816 3.35105976125509e-30 676.568483687684 341.672757689981 1.98016513889461 0.0486963250101694 NSUN2 other 5.79365988591385e-25 1 5.28663187935603e-26 12.9555635790816 1.98016513889461 1.8337775650581e-17 171.73029019832 32.5439530066772 5.27687248574521 2.6809163730846e-07 -187.584292981422 50.5488714219402 -3.71094918055881 0.000250208684141924 FBXO42 other 2.57278992377652e-13 1 0.00309163276144116 5.27687248574521 -3.71094918055881 3.55114181711638e-05 77.881384761826 20.5786519943462 3.78457173886915 0.000189574831697088 -19.0451889252161 34.2731213039433 -0.555688778863128 0.578882084473311 MFAP3 other 0.276065764862627 1 1 3.78457173886915 -0.555688778863128 1.37367541703931e-13 190.524031664534 33.6334129137508 5.66472490178477 3.78002346253073e-08 -192.250917429326 73.5294608862935 -2.61461073033875 0.00943667127951605 MRI1 other 1.7437435743897e-09 1 0.000456173231458209 5.66472490178477 -2.61461073033875 1.49555936382491e-07 103.259377025523 22.6855974900772 4.55175919746832 8.02919680645634e-06 -105.867676014137 58.805133949861 -1.80031349141052 0.0729190023946773 METTL1 essential 0.00141569649379666 1 0.0830941577500166 4.55175919746832 -1.80031349141052 0.000206526393863005 38.70291270204 11.1308337731192 3.47709017050519 0.00058992031676485 -32.85870278805 30.5413274181213 -1.07587670759044 0.28293576547229 HOXC8 other 1 1 1 3.47709017050519 -1.07587670759044 1.04606850391506e-08 140.372553420867 36.4472719494832 3.85138711109644 0.000146516938026085 -86.4935767978447 53.7351598065593 -1.60962723678895 0.108639187695014 AGA other 0.000106458391643436 1 1 3.85138711109644 -1.60962723678895 8.55524491127397e-10 52.5864652474082 30.1775805296798 1.74256730739859 0.0825605781206178 -162.869808200324 43.4709782992179 -3.74663314635489 0.000219629860817209 PI4K2B other 9.28072967975e-06 1 1 1.74256730739859 -3.74663314635489 2.61638343810295e-15 223.009586099179 70.1765169864248 3.1778377679006 0.00165630316426158 -411.935273609639 102.371031188791 -4.02394377419091 7.43725716265663e-05 BOD1L1 other 3.4868542079598e-11 1 1 3.1778377679006 -4.02394377419091 4.89029529884663e-10 314.99421695169 89.3816316008184 3.52414932811325 0.000497965345530815 -484.272873723907 143.973427153071 -3.36362676988326 0.000879437713174663 MAT2B other 5.37687968108187e-06 1 1 3.52414932811325 -3.36362676988326 0.000244454171950981 -4.82135689031786 19.608176440745 -0.245885021735079 0.805957360941274 -98.5052569727557 28.5711935065381 -3.44771235931093 0.00065526108714014 TLL1 other 1 1 1 -0.245885021735079 -3.44771235931093 2.57794398828794e-16 386.471533753918 63.4385726793284 6.09205909640288 3.82495592734787e-09 -260.987916915964 114.303699143422 -2.28328495815775 0.0231907732805594 EDC4 essential 3.5230182543943e-12 1 4.83589177894591e-05 6.09205909640288 -2.28328495815775 6.7226342918025e-19 884.44001262571 89.5873557324635 9.87237546408815 1.04401961224628e-19 44.5779337613624 596.357838412077 0.0747503107866581 0.940471302610008 TRIO other 9.67521527276216e-15 1 1.59620158516334e-15 9.87237546408815 0.0747503107866581 0.0210016222033847 -810.962597114315 682.351508083646 -1.18848216426145 0.235680126477761 1733.1243567753 1069.93884595362 1.61983496844681 0.106426512347936 VCAN other 1 1 1 -1.18848216426145 1.61983496844681 1.23974608204756e-06 128.846752341647 39.3360950592712 3.27553490369346 0.00119349700842905 -159.728562714292 76.3906998241128 -2.09094252418242 0.0374750887305235 CLEC16A other 0.0109593553653004 1 1 3.27553490369346 -2.09094252418242 0.441470421353123 -213.98040558818 223.157843437088 -0.958874679430685 0.338479725132669 -473.062323842265 376.598031564379 -1.25614656528388 0.210148650454563 MSR1 other 1 1 1 -0.958874679430685 -1.25614656528388 4.01562515101665e-08 1881.33353290397 573.887705359038 3.27822588868142 0.00118155564981141 -2796.65185723937 1056.86270229877 -2.64618275501293 0.00861831907922229 CDH1 ts 0.000394213921075305 1 1 3.27822588868142 -2.64618275501293 4.55514347445618e-30 422.811064537834 51.2156525648578 8.25550477956713 6.69979436917524e-15 -375.97864650579 92.8251523611747 -4.0503962228135 6.68110380312888e-05 SKIV2L2 essential 7.13699879577794e-26 1 9.78705961449119e-11 8.25550477956713 -4.0503962228135 2.92035533291231e-08 175.783801152119 29.4897257600771 5.96084896083006 8.1403988265146e-09 -101.539699342153 192.351079509997 -0.52788733809459 0.598027756117164 DNAH5 other 0.000289494824151597 1 0.000101470071372504 5.96084896083006 -0.52788733809459 1.12978829368625e-07 64.3619886230333 37.3817036852787 1.72175107814521 0.0862473539362424 -234.159131147904 58.6688407578466 -3.99120091897481 8.45351684283342e-05 ZFYVE16 other 0.00107849590515289 1 1 1.72175107814521 -3.99120091897481 0.0109465909260142 192.389889027736 98.638706863947 1.95045023545473 0.0521570692772858 -146.367246503801 173.912758244291 -0.841613047722479 0.400749375147119 RIPOR1 other 1 1 1 1.95045023545473 -0.841613047722479 0.0690070810566589 7.68763812262176 4.83073194108449 1.59140234158716 0.112757943073454 -43.9822930689679 31.3429123970296 -1.40326120661129 0.161755446195024 C6 other 1 1 1 1.59140234158716 -1.40326120661129 3.40731233613724e-09 1191.61803701055 191.770262391605 6.21377904034568 1.96867223554971e-09 -817.551265436438 1241.00282935765 -0.658782757054317 0.510600868645437 RAI14 other 3.56677455346846e-05 1 2.51675058592675e-05 6.21377904034568 -0.658782757054317 5.85658754636502e-13 216.738827600604 58.1416729671433 3.72777074583124 0.000235010634357061 -606.405349744676 121.574885369642 -4.98791627811069 1.08955657977883e-06 PNKP essential 7.28208095515027e-09 0.0170504709169589 1 3.72777074583124 -4.98791627811069 7.72256121864102e-10 54.0180342199743 14.5094469105803 3.7229561231989 0.000239482989103898 -66.8629824696037 25.137968604287 -2.65984032051822 0.00828349909064509 PHLPP2 other 8.40214660588143e-06 1 1 3.7229561231989 -2.65984032051822 1.09485661198384e-09 142.832869242827 24.9928463795212 5.71495007306821 2.86909270310106e-08 -11.3427110537394 40.2308870420308 -0.281940366909862 0.778202845558205 SPDL1 essential 1.17948902809019e-05 1 0.000348307854156468 5.71495007306821 -0.281940366909862 5.64351306014026e-15 262.701141473539 31.8723329438907 8.24229409048934 7.68300047544591e-15 24.0646835005187 106.872593545558 0.225171699330572 0.82201794735425 STAU2 other 7.45508075244529e-11 1 1.12094976936756e-10 8.24229409048934 0.225171699330572 4.38390556791086e-12 99.3699530829845 23.9252233197994 4.1533553001677 4.38995741808065e-05 -92.9556859654594 35.135462863788 -2.64563715371638 0.00862831316032003 PQLC2 other 5.26463219650415e-08 1 0.426616061889078 4.1533553001677 -2.64563715371638 9.15767929163221e-12 101.760819427486 15.0704909356974 6.75232279171781 8.72829001138141e-11 -53.4582824582831 45.2114728070921 -1.18240524227951 0.238073741998502 CTNS other 1.08729126229549e-07 1 1.16854346672374e-06 6.75232279171781 -1.18240524227951 1.20566305352542e-37 276.664995872332 18.1677828228697 15.22833020241 9.29114629167963e-38 76.7498764695926 80.8776035334852 0.948963286700457 0.343530773575759 RTN4R other 1.91013197570033e-33 1 1.47496947380414e-33 15.22833020241 0.948963286700457 2.43982542873576e-17 209.765530877595 24.3024173738909 8.63146771164234 5.24609294138178e-16 -92.1677772409173 72.7105355279344 -1.26759865776958 0.206029390831768 PHF23 other 3.41575560023007e-13 1 7.77366052053952e-12 8.63146771164234 -1.26759865776958 6.09078641884305e-05 293.372452239054 67.5174560439157 4.34513486480051 1.97980894717575e-05 -124.901269249506 300.529756985421 -0.415603667677957 0.678033854829031 INPP4A other 0.462717044239506 1 0.198317462238595 4.34513486480051 -0.415603667677957 0.0167917824393976 -48.5627246479286 65.5670124894844 -0.74065788273817 0.459551742865428 -299.891988013166 109.403401726938 -2.74115780020873 0.00653571559359153 RAB27B other 1 1 1 -0.74065788273817 -2.74115780020873 1.17638394204547e-09 843.097789041625 141.014606305327 5.97879759502457 7.01353540960896e-09 -181.535320428264 273.258892119139 -0.66433454011486 0.50703693629639 PSMA4 other 1.26531856806411e-05 1 8.76236090000969e-05 5.97879759502457 -0.66433454011486 0.401126195385646 2.36341725432795 5.04274517401468 0.468676717298083 0.63968603245121 -8.80375166243412 9.26154715750121 -0.950570300266051 0.342688682876769 MYO16 other 1 1 1 0.468676717298083 -0.950570300266051 5.56916958028046e-22 483.970781146624 45.7160940509673 10.5864420658305 3.91563390067626e-22 -440.834100132574 352.05674740814 -1.25216773539498 0.21159232753376 LSG1 essential 8.33537611080576e-18 1 6.05317844705543e-18 10.5864420658305 -1.25216773539498 8.22834170975741e-05 1.10343252939 33.3334233366779 0.0331028865005849 0.973616908526227 -327.075989829543 78.7887665226632 -4.15130232728622 4.43173446329107e-05 PARP3 other 0.61630279406083 0.67038847226204 1 0.0331028865005849 -4.15130232728622 0.204279850525932 3656.06872046781 2055.44699287036 1.77872196809232 0.0764063052985326 3552.39037074758 3821.7020373363 0.929530961870478 0.353441215064731 TNC other 1 1 1 1.77872196809232 0.929530961870478 2.54626959766008e-19 199.356140662048 34.9714830935817 5.70053435047587 3.12502931884181e-08 -213.545997087433 55.3805213426692 -3.85597664865068 0.000144164142577724 THAP3 other 3.6854706156532e-15 1 0.000378753553443628 5.70053435047587 -3.85597664865068 0.857670458355313 -1.45682826332009 13.8534865242504 -0.105159683865136 0.916327180399617 -25.3964856799537 46.0021601816016 -0.55207158924052 0.581355978793672 RIPOR3 other 1 1 1 -0.105159683865136 -0.55207158924052 5.87690814647977e-26 181.984206617998 17.0693651737607 10.6614513642105 2.28489080210451e-22 -23.8563281279267 36.7509182902927 -0.649135565524848 0.516804591088083 TDP1 other 9.0510262363935e-22 1 3.53541153809631e-18 10.6614513642105 -0.649135565524848 5.67412394543907e-06 154.451092226398 50.987867993375 3.02917337603656 0.00268802676539629 -98.5560233153568 79.7944729222953 -1.23512343281385 0.217850381422242 AIFM2 other 0.0474243279359797 1 1 3.02917337603656 -1.23512343281385 0.000580637294969178 14.9576621510891 7.38888449192662 2.02434645817409 0.0439189414183804 -30.8436722250116 14.7568114951098 -2.09013120722134 0.0375415169505827 SPATA7 other 1 1 1 2.02434645817409 -2.09013120722134 1.63816283646122e-15 164.483438557274 28.0596576722331 5.86191893281866 1.34071668773617e-08 -119.050807412139 49.94958898192 -2.38341915997009 0.0178495072049136 MED17 essential 2.1946467520071e-11 1 0.00016551147510103 5.86191893281866 -2.38341915997009 0.0177738014020572 110.346497616526 46.150272575096 2.39102591294492 0.0174942957616445 -242.281128619351 190.083356141695 -1.27460464470517 0.203557357627258 RETSAT other 1 1 1 2.39102591294492 -1.27460464470517 0.211192315839934 -204.942813162077 186.934773412517 -1.09633327936168 0.273920798793476 -1161.45824174612 769.945379022814 -1.50849433400094 0.132610415270046 CAPG other 1 1 1 -1.09633327936168 -1.50849433400094 1.2857382024434e-13 342.095223692742 73.965830827918 4.62504402186233 5.79733407513055e-06 -711.393202635452 170.478788891808 -4.17291328299456 4.05027937161342e-05 AP2S1 essential 1.63327323856385e-09 0.61333380524342 0.0606748984303164 4.62504402186233 -4.17291328299456 0.207175011524933 17.4325511508688 10.8474385325656 1.60706613810567 0.109208637312664 -23.7719988818134 46.651471032059 -0.50956590126552 0.610771847986814 TG other 1 1 1 1.60706613810567 -0.50956590126552 0.00193368565317551 -67.6946176358308 69.4148029219579 -0.975218754304308 0.330318265956372 -385.731978502051 116.695028743299 -3.30547052994494 0.0010755433223639 ADAM28 other 1 1 1 -0.975218754304308 -3.30547052994494 0.0230563302773193 75.9149191703304 69.2119515862997 1.0968469668952 0.273685584664488 -206.14372909262 127.206046688056 -1.62054976520213 0.106281504541342 BARX2 other 1 1 1 1.0968469668952 -1.62054976520213 2.42942267787388e-31 368.086477457241 26.8904006581016 13.6883969167021 2.24134513871507e-32 237.65857745361 288.681792243957 0.823254475477176 0.411129534488686 DCUN1D1 other 3.81565125786871e-27 1 3.54401493333627e-28 13.6883969167021 0.823254475477176 8.09045598149381e-06 472.304816230519 203.002028056797 2.32660146675173 0.0207185167209977 -876.830360818246 330.205388347066 -2.65540900228025 0.008386785671641 JADE2 other 0.0667867141272314 1 1 2.32660146675173 -2.65540900228025 0.00261804225856062 49.5357335204742 38.3003160099601 1.2933505172018 0.196991215587252 -159.935028479102 69.0989538325757 -2.31457959358717 0.0213836525902667 ZIC2 other 1 1 1 1.2933505172018 -2.31457959358717 0.217212574182669 -102.866337239033 79.2192201812619 -1.29850227007618 0.195210596431622 -212.586166262756 128.389179010653 -1.65579504363929 0.0989123034298681 LCP2 other 1 1 1 -1.29850227007618 -1.65579504363929 3.28795204657888e-34 296.07146464375 21.7565161109493 13.6084041734397 1.91678814789608e-32 -19.9722983951008 59.702438707498 -0.334530696358178 0.73823981359758 TRIT1 other 5.18871712470613e-30 1 3.03140045589765e-28 13.6084041734397 -0.334530696358178 0.506108252832554 -5.98154436860063 25.7945366491462 -0.231891909901728 0.816795694642255 -38.9842491467575 36.3205351079028 -1.07333906372638 0.284066836899306 ADRB1 other 1 1 1 -0.231891909901728 -1.07333906372638 3.77138809950656e-25 742.268793968184 69.5614585523871 10.6706904860136 1.95857487106421e-22 -193.363410039175 169.379512613851 -1.14159857384879 0.254624935720467 CUL7 other 5.78153795654355e-21 1 3.0318739004074e-18 10.6706904860136 -1.14159857384879 3.26262155493341e-09 1101.08392455173 328.711445161706 3.34969755619572 0.000923447407244462 -1795.79210587597 544.914156008036 -3.29555047538439 0.00111271557812574 CTNNA1 ts 3.4198799138812e-05 1 1 3.34969755619572 -3.29555047538439 1.291474775949e-18 143.490619079289 18.7034888187901 7.67186381479447 3.44559265475525e-13 -206.901934867292 62.9616429908094 -3.28615844566657 0.0011559587881975 CNTLN other 1.84900443672618e-14 1 4.90686849963696e-09 7.67186381479447 -3.28615844566657 0.952749926564161 0.384816589591843 25.4446635259846 0.0151236658798361 0.987947610697721 14.9109488236485 52.3382757005083 0.284895683399515 0.775999580004614 EPHA3 other 1 1 1 0.0151236658798361 0.284895683399515 0.00532886917996045 2309.99449740324 781.620378858929 2.95539184990999 0.00339532488553977 -71.2134173497122 1503.31376009123 -0.0473709608999991 0.962252207913888 HSPA5 essential 1 1 1 2.95539184990999 -0.0473709608999991 1.07042064346395e-13 2671.35744110995 439.290232602795 6.08107634281362 4.13188702282456e-09 -1991.00127703878 846.777501089857 -2.35126851442821 0.0194395236572312 DSG2 other 1.36318068945134e-09 1 5.21568098891144e-05 6.08107634281362 -2.35126851442821 0.00990485729751158 42.1201300089804 15.3588904266245 2.74239406877761 0.00650719652182869 -15.8873763575045 49.0810207339202 -0.323696942727286 0.746418072867266 PREX2 other 1 1 1 2.74239406877761 -0.323696942727286 5.65009301921138e-13 13.7499080904882 26.0691723531199 0.527439379518413 0.598343530845754 -272.632549500598 44.4651681376541 -6.13137340798058 3.26583818467402e-09 WDR37 other 7.02928072520088e-09 5.19529538417943e-05 1 0.527439379518413 -6.13137340798058 1.0323518768539e-07 102.326011258303 31.9248312778381 3.2052169788392 0.0015099502895108 -147.488993273717 52.6094902023609 -2.80346744867523 0.00541822377982643 YTHDC2 other 0.000988476922087605 1 1 3.2052169788392 -2.80346744867523 4.43575655160204e-18 224.834059468221 29.8454996284642 7.53326505728163 9.13051972768444e-13 -298.069007211237 97.152466725502 -3.06805392860905 0.0023926537249525 ATP6V1H essential 6.29389497106813e-14 1 1.28722067120895e-08 7.53326505728163 -3.06805392860905 6.77187452350349e-42 1300.07689209057 91.3458915322444 14.2324615840183 2.37692349727353e-34 -347.515147382907 200.593280199597 -1.73243663515107 0.0843862900146442 POLR2B essential 1.07537367433235e-37 1 3.76623528142992e-30 14.2324615840183 -1.73243663515107 3.4585831531871e-08 -19.5935721928151 28.7013508135156 -0.682670732820993 0.49539806313859 -321.315007698544 56.0514437703372 -5.73250189620604 2.63366877995036e-08 FAM214A other 0.000340774198083525 0.000417778878563526 1 -0.682670732820993 -5.73250189620604 1.00328256383444e-08 85.5113891659796 62.2055904153093 1.37465762474195 0.170381630114031 -385.56633560307 98.279870454679 -3.92314655910003 0.000111031047672102 ARAP2 other 0.00010223449325473 1 1 1.37465762474195 -3.92314655910003 5.15718451326727e-06 549.954017736898 119.672658592591 4.59548592138443 6.71754949907619e-06 -733.918483086101 370.072449300132 -1.98317514441851 0.0483919260698097 TPR essential 0.0432739352508256 1 0.0699699955823776 4.59548592138443 -1.98317514441851 0.4151806494587 326.312317648932 290.98812576566 1.12139392901454 0.263127751732639 1496.25140765552 1804.18384850771 0.829323136271902 0.407662390740474 CP other 1 1 1 1.12139392901454 0.829323136271902 7.13547174649669e-64 691.352993207855 30.3866667142627 22.7518536241211 3.57856240361334e-64 419.415464058455 96.2179198736374 4.35901612308052 1.87339794285743e-05 KIAA0556 other 1.13789367941383e-59 0.286311407606901 5.70673346504219e-60 22.7518536241211 4.35901612308052 9.4973112651563e-15 131.542492371827 16.4054140625037 8.01823665472009 3.19867805325874e-14 2.60390708404185 30.982820430737 0.0840435779519479 0.933083605278328 DTNBP1 other 1.24652210355176e-10 1 4.62464872940149e-10 8.01823665472009 0.0840435779519479 0.381959099827707 -0.452143688968716 2.22048784938148 -0.203623581680333 0.838800480702311 -14.107727767611 10.1630917168419 -1.38813346968346 0.166236487451455 ANO2 other 1 1 1 -0.203623581680333 -1.38813346968346 9.10401287056221e-17 110.362323631086 11.980253402975 9.21201913839982 8.96719061624265e-18 87.6466854675585 55.2771236996532 1.58558694087964 0.113994903971885 C12orf4 other 1.25735521755335e-12 1 1.35171431349242e-13 9.21201913839982 1.58558694087964 5.64912319764573e-09 45.0822918506017 15.4501256235183 2.91792396703734 0.00382028159374472 -51.5762776647826 22.2441604355482 -2.31864348462255 0.0211613884220794 FAM184B other 5.84006356172616e-05 1 1 2.91792396703734 -2.31864348462255 0.397588629555786 395.62358342535 329.281128704031 1.20147663785783 0.230607632188478 -195.301388969605 822.46636767595 -0.237458206979903 0.812479442607669 MAP4 other 1 1 1 1.20147663785783 -0.237458206979903 3.08471177168984e-11 152.815766086519 41.1554196945483 3.71313832347486 0.000248327395222261 -335.606074155033 74.446529846915 -4.50801501218583 9.73330754542956e-06 GOPC other 3.58782826165246e-07 0.149785869816615 1 3.71313832347486 -4.50801501218583 0.410077955310017 -40.3326046996871 105.214464594174 -0.383337071145637 0.701769289489388 -253.790468147118 190.323700666208 -1.33346749384733 0.183494061519672 ROS1 og 1 1 1 -0.383337071145637 -1.33346749384733 6.77229627335606e-17 431.585028947223 52.8078035005936 8.17275100151385 1.13697274181319e-14 64.5255185206004 93.3497048465413 0.691223594404232 0.490012390749796 USP28 other 9.3884343237535e-13 1 1.65577340390255e-10 8.17275100151385 0.691223594404232 0.697060623170472 6.21824740557166 162.808168436422 0.0381937065276914 0.969561567808599 -355.93281443385 440.433546639255 -0.808141925495479 0.419722973774377 HDAC9 other 1 1 1 0.0381937065276914 -0.808141925495479 1.23744322386267e-07 289.706021324566 68.129994576583 4.25225369714239 2.90929117280838e-05 -174.773084575538 113.408864381445 -1.54108839312329 0.124453567336551 TSPAN17 other 0.00117816969343965 1 0.287583432432108 4.25225369714239 -1.54108839312329 2.95931595920707e-12 251.848108970715 46.9182083259095 5.36781172932467 1.70438140040612e-07 -185.298485190788 78.0137421852555 -2.37520313729815 0.0182302364650944 NOP16 essential 3.58047637904464e-08 1 0.00198782002729366 5.36781172932467 -2.37520313729815 4.0383274319714e-05 75.7266333235766 28.6146603054137 2.64642782808957 0.00861403487057394 -44.0791325705997 41.9187357017869 -1.0515377392148 0.293955382539866 CC2D2A other 0.31212232721707 1 1 2.64642782808957 -1.0515377392148 2.13326344428188e-07 137.319077860404 26.6128274125315 5.15988307938085 4.76007162058623e-07 -129.474370360114 106.446053530749 -1.21633791075882 0.224906829730407 RRM2B other 0.00200078778439198 1 0.00538982909598978 5.15988307938085 -1.21633791075882 6.71953597954309e-17 87.2898095871161 13.5443022995872 6.44476235514741 5.21981154789144e-10 -128.193362053733 36.3110000697496 -3.53042774386514 0.000486802298252658 ZNF800 other 9.31596468203854e-13 1 6.81133208884354e-06 6.44476235514741 -3.53042774386514 0.0158545329863066 -23.5729451195599 9.58389561846701 -2.45964126259239 0.0145394784188286 -47.5016830683893 18.5898644264976 -2.55524634169367 0.011164047127234 TNFRSF17 other 1 1 1 -2.45964126259239 -2.55524634169367 3.59565013445149e-05 241.645861601085 62.0251008889857 3.8959366149777 0.000123617621269225 -26.9471848966317 124.59237411765 -0.216282778841553 0.828931865112657 SNX29 other 0.279417971948225 1 1 3.8959366149777 -0.216282778841553 0.879063645204706 36.1572875963138 75.7744955472472 0.477169624623484 0.633630221415459 92.1332833588702 320.947221144015 0.28706677387784 0.774283016136438 LMO3 other 1 1 1 0.477169624623484 0.28706677387784 4.91408137340981e-22 351.444513773504 36.9713410985143 9.50586328034574 1.1158633593016e-18 -137.015981438034 83.5108364092513 -1.64069703201841 0.102020413914074 MRPS10 essential 7.35785404040651e-18 1 1.69499644277913e-14 9.50586328034574 -1.64069703201841 0.0869192376582435 84.578224486164 38.5682224970427 2.19295106204724 0.0291609037801974 39.2411649756465 87.1129993439128 0.450462792822993 0.652736943950876 GUCA1A other 1 1 1 2.19295106204724 0.450462792822993 7.76324202888276e-15 347.707702782723 45.5743786389818 7.62945569784056 4.019540388179e-13 -73.9358056168726 116.02792807693 -0.637224216982063 0.524516761535446 RSF1 other 1.02125448889953e-10 1 5.716992294107e-09 7.62945569784056 -0.637224216982063 2.59595159159153e-06 297.824763076068 96.6669084581121 3.08093811860263 0.00227506203930429 -275.045971876146 153.549222863048 -1.79125603339238 0.0743639232469454 VPS13D essential 0.0223225877360956 1 1 3.08093811860263 -1.79125603339238 0.226364212773689 -26.7964972101674 122.703405291941 -0.218384299493661 0.827292855913468 -317.136565593944 207.574912476269 -1.52781741208827 0.127715643000364 CELF2 other 1 1 1 -0.218384299493661 -1.52781741208827 1.51186843004837e-19 871.903718959462 157.820378106738 5.52465866207575 7.83579562142464e-08 -1606.27800661411 301.393903704763 -5.32949733511389 2.09659121447934e-07 FAM120A other 2.19614008148826e-15 0.00330590502699103 0.000931832815299818 5.52465866207575 -5.32949733511389 9.06681715073038e-07 199.762419396053 49.3610148086588 4.04696743311304 6.7934800080481e-05 -218.938060094094 119.360622272308 -1.83425702653101 0.0677244565379778 R3HDM1 other 0.00809848107903238 1 0.64830179716803 4.04696743311304 -1.83425702653101 0.0107200082152465 366.203585005748 160.118316883766 2.28708115431655 0.0229621683931358 -279.737842528698 317.009532938419 -0.882427225250158 0.378327866991847 COL9A2 other 1 1 1 2.28708115431655 -0.882427225250158 0.929488447236654 15.4954270721984 119.778186780445 0.129367687796124 0.897162325262335 -87.9411058206208 283.349668946121 -0.310362479503524 0.75652300024764 KITLG other 1 1 1 0.129367687796124 -0.310362479503524 8.79866415588454e-25 64.9859680613133 7.71296719822009 8.42554705487533 2.21888204329755e-15 -33.1257705355745 13.9135619194729 -2.38082604061387 0.0179729507081999 ERCC8 other 1.34522776279319e-20 1 3.26197849185173e-11 8.42554705487533 -2.38082604061387 0.0316156732284128 13.9642224426886 5.28005692394012 2.64471058623893 0.00865314237019974 11.8570935052971 8.36576945848622 1.41733448000641 0.157533817331791 ADAMTS6 other 1 1 1 2.64471058623893 1.41733448000641 0.0603362089383918 230.671867009464 162.013059694734 1.4237856345908 0.155650450294877 -223.475799841678 256.916978296444 -0.869836634867395 0.385153833531652 H6PD other 1 1 1 1.4237856345908 -0.869836634867395 2.70267333780339e-14 555.501834051767 112.542365811539 4.93593528131442 1.39261223272478e-06 -571.190309406605 180.104697656567 -3.17143482007216 0.0016905678719218 VAMP3 other 3.50482678446343e-10 1 0.0152839192541545 4.93593528131442 -3.17143482007216 5.80415086720083e-06 200.703033998938 78.1323542590253 2.56875702648822 0.010740250518022 -290.390471910348 125.037393158966 -2.32242903161905 0.0209481236217896 PER3 other 0.0484704638919941 1 1 2.56875702648822 -2.32242903161905 6.36810156749574e-06 29.178605039621 12.1065931334071 2.41014170692705 0.0166102957401921 -47.7231124523288 19.3745198105636 -2.46318943225156 0.0143902823472952 UTS2 other 0.052950764533727 1 1 2.41014170692705 -2.46318943225156 0.204114286162214 24.362008037135 39.6109519999997 0.615032126396134 0.539047695982522 -70.0841894057847 63.3905150509755 -1.10559425727061 0.269879115680377 TNFRSF9 other 1 1 1 0.615032126396134 -1.10559425727061 0.000482813938552411 131.549252226378 43.1259262075091 3.05035192968151 0.00251223621046108 -133.049502969234 95.2821371064982 -1.39637404249783 0.163744552517735 EPN3 other 1 1 1 3.05035192968151 -1.39637404249783 0.182700883326385 600.316285287157 362.158483923912 1.65760657815566 0.0985582883552669 1283.79203369885 1393.2720152451 0.921422392506041 0.357652516029961 LTBP1 other 1 1 1 1.65760657815566 0.921422392506041 0.442000862525648 -200.739144922336 158.796852472341 -1.2641254646864 0.207271199734418 -307.800856743733 534.520493548822 -0.575844818783582 0.565197953620954 ELN other 1 1 1 -1.2641254646864 -0.575844818783582 1.54534464445018e-17 285.434626031681 33.4753903692701 8.52670044719497 1.07360984534982e-15 -147.893394038037 112.680332785805 -1.31250405799892 0.190460608501033 RFC2 essential 2.1715182943814e-13 1 1.58411132681367e-11 8.52670044719497 -1.31250405799892 7.67134178085139e-15 747.007973428385 103.928243900538 7.18772823818026 6.31175647376268e-12 -459.115832067739 205.975979600508 -2.22897753882854 0.0266294485051239 ARID1B other 1.00947186494223e-10 1 8.72284744674002e-08 7.18772823818026 -2.22897753882854 5.15068390583464e-36 1326.75176786535 88.9324010002507 14.9186545392113 5.09283628532263e-37 365.757298481961 516.885275908648 0.707617948371591 0.479799744062584 CLPTM1L other 8.14683673385865e-32 1 8.08131261754995e-33 14.9186545392113 0.707617948371591 5.3413223732905e-14 733.287866954563 154.528572089039 4.74532222126563 3.37876073683374e-06 -826.219833868223 259.177104314188 -3.18785810982221 0.00160199214056506 NEDD4L other 6.86787230757693e-10 1 0.0360277257368582 4.74532222126563 -3.18785810982221 8.30667957349671e-05 345.623728904347 138.20858812499 2.50073988594529 0.0129820193440093 -425.227690932162 216.359142496123 -1.96537888820567 0.0503877744622732 HEXB other 0.621588832484759 1 1 2.50073988594529 -1.96537888820567 3.32902591636657e-15 79.1730085423648 11.5188529836145 6.87334135221519 4.30645469261703e-11 -21.8735247064504 17.9241755980054 -1.22033644375167 0.223398181396341 PTCD2 other 4.42660576099263e-11 1 5.81888158066414e-07 6.87334135221519 -1.22033644375167 2.43492733352811e-14 176.937263013754 31.9769914649579 5.53326798137503 7.38743673070456e-08 -159.672266819073 59.2858630571255 -2.69326039270473 0.00751523371283878 JKAMP other 3.1615096498529e-10 1 0.000879326594055764 5.53326798137503 -2.69326039270473 0.021326362510888 145.599022745606 278.406942041509 0.522971954930269 0.601429108386781 -841.297894613709 436.751431298329 -1.92626247866615 0.0551371224931897 DKK3 other 1 1 1 0.522971954930269 -1.92626247866615 0.019735957286574 24.6474892697816 103.699583106537 0.237681662080162 0.812306288287995 -753.841813766635 289.920630850175 -2.60016616118708 0.00982524678870489 NFE2L3 other 1 1 1 0.237681662080162 -2.60016616118708 6.89247353222153e-14 269.230211549393 35.7468365680459 7.53158145999578 7.42438191058612e-13 -29.7246386426928 67.7424765081064 -0.438788780317705 0.661162923416674 MCUR1 other 8.82994784212901e-10 1 1.04854545723208e-08 7.53158145999578 -0.438788780317705 0.0169403706229431 199.002320891832 234.165779844659 0.849835193783851 0.396164119947468 -1366.62192608657 597.657227993399 -2.286631637795 0.0229859457617731 LIMA1 other 1 1 1 0.849835193783851 -2.286631637795 2.6796933456685e-08 193.626000036365 39.5922845200081 4.89049829742751 1.71980928552818e-06 -168.308252118259 100.8086579868 -1.66958131850438 0.0961484430016392 LETMD1 other 0.000266093549224882 1 0.0187493608308283 4.89049829742751 -1.66958131850438 0.105868335648529 41.1323593585222 21.0595490414165 1.9531453060856 0.0518238776513636 -5.14743263391394 53.6211765097706 -0.0959962643299331 0.923593968807131 SLC4A8 other 1 1 1 1.9531453060856 -0.0959962643299331 0.735340031515056 31.8290643381538 49.9450216041986 0.63728202162752 0.524475233569919 -16.5054662860323 97.1704609055651 -0.169860944696693 0.86524530048193 LAMC3 other 1 1 1 0.63728202162752 -0.169860944696693 0.903621013764306 -3.50972399393217 12.2621137801093 -0.28622503891828 0.774924448594589 -8.63034116668535 19.2344812749992 -0.448691131478705 0.654013044427308 PTGER3 other 1 1 1 -0.28622503891828 -0.448691131478705 0.0112895949530252 -34.519354398727 31.4073818271623 -1.09908411304993 0.272714072899571 -134.72378154126 46.135392407227 -2.92018284687127 0.00379467213657414 TNIP3 other 1 1 1 -1.09908411304993 -2.92018284687127 1.15616317095942e-16 252.428673213794 37.7903284427315 6.67971630879924 1.34586755554566e-10 -169.577808429735 62.0730204950309 -2.73190843747181 0.00670897842925427 MAPK9 other 1.59261476799661e-12 1 1.79256099723127e-06 6.67971630879924 -2.73190843747181 0.932929597802934 8.17563765419037 28.9203017572227 0.282695447745408 0.77762452642648 16.6621825657712 48.5006580284626 0.343545494908399 0.731452547467802 COL23A1 other 1 1 1 0.282695447745408 0.343545494908399 2.08938754105096e-07 307.847106775584 126.589169870131 2.43185974828184 0.0156720565500238 -604.371502487954 214.441055326119 -2.81835724772402 0.00518404105903882 BCAR1 other 0.00196047232976812 1 1 2.43185974828184 -2.81835724772402 2.24162540206884e-15 141.515539281647 39.5554370114348 3.57765075988763 0.000410059063495486 -245.574303677269 60.0391303064549 -4.09023752382481 5.67576109997598e-05 FAM160A2 other 2.9927940743021e-11 0.854883136878382 1 3.57765075988763 -4.09023752382481 0.00646412743276122 157.310209272748 168.974359563352 0.930970886229454 0.352691147987875 -581.55369278401 303.183337010621 -1.91815849287138 0.0561339368982908 HERPUD1 other 1 1 1 0.930970886229454 -1.91815849287138 6.63545343518628e-06 289.165418975218 69.7497438331559 4.14575599971969 4.52913286859122e-05 -100.930318257956 161.32831407332 -0.625620609982237 0.532088385982367 HOMER3 other 0.0550941698723517 1 0.439371179582034 4.14575599971969 -0.625620609982237 1.34934118456763e-13 164.572499666861 23.4680132095434 7.01263026390051 1.86415618276019e-11 1.57526177476557 40.7894967312777 0.038619299108872 0.969222349247251 RAD51 essential 1.71312356792707e-09 1 2.54587809879559e-07 7.01263026390051 0.038619299108872 1.12434654999842e-12 134.003163858435 17.9867362325111 7.4501100214181 1.26328322796254e-12 -75.2677086727563 69.6929868260229 -1.07998971059527 0.281110532231428 POLQ other 1.38272138718806e-08 1 1.77567090522415e-08 7.4501100214181 -1.07998971059527 2.69304381710101e-05 135.430020538836 37.5306663815039 3.60851627738694 0.000367354093639159 -475.591829369893 192.985370963413 -2.46439316615381 0.0143524239289816 PIK3CB other 0.212104131034875 1 1 3.60851627738694 -2.46439316615381 0.0125999905716469 24.7076480982693 195.32536955599 0.126494823250223 0.899434393117627 -751.134414608775 320.83351797481 -2.34119682803139 0.0199497590477066 CYBA other 1 1 1 0.126494823250223 -2.34119682803139 8.59402057780702e-05 484.591892238028 114.790720048852 4.22152498069354 3.30763673632702e-05 159.250382407667 190.869471761258 0.834341819769166 0.404817868063443 THOC3 essential 0.642145217573741 1 0.324843003874677 4.22152498069354 0.834341819769166 1.23084941992727e-05 379.4066106654 108.451923561949 3.49838525868727 0.000546941397925372 -425.894543641039 198.229716961695 -2.14848989429439 0.0325610452576477 HEBP2 other 0.100043440851688 1 1 3.49838525868727 -2.14848989429439 5.05847671371226e-07 117.264815223963 23.4648349757484 4.99747027179863 1.04128018703239e-06 -44.3001279225857 48.8334633789305 -0.907167439237972 0.365121230701799 MPHOSPH9 other 0.00461838923961929 1 0.0115363431921319 4.99747027179863 -0.907167439237972 1.46602157632263e-12 416.783675468694 53.7321728031652 7.7566875435222 1.86688748988905e-13 297.456658696228 240.486500996533 1.23689544928144 0.217216793044163 PLEKHA5 other 1.79587643099523e-08 1 2.66852897804742e-09 7.7566875435222 1.23689544928144 0.00104708662814983 343.280679432727 198.065109864796 1.73317087329039 0.0842241728036112 -830.18689078468 408.74629570596 -2.03105667135365 0.0432436087552461 PRSS8 other 1 1 1 1.73317087329039 -2.03105667135365 6.16451898139037e-27 139.552531626642 44.376864390781 3.14471365975179 0.00184609502010113 -462.484338706622 65.172643349009 -7.09629554581592 1.10557656233407e-11 SIKE1 other 9.53897667180345e-23 1.76350517457908e-07 1 3.14471365975179 -7.09629554581592 1.13045498090443e-13 380.184977504327 66.1998473141872 5.74298873681617 2.4756252763434e-08 -238.493804438033 105.446045205719 -2.26176149112796 0.0244988319218563 RRP12 essential 1.43884309969515e-09 1 0.000301531158658627 5.74298873681617 -2.26176149112796 2.57689870780077e-07 92.0206749949732 72.2073698339484 1.27439450026484 0.203611324903621 -395.595724455002 106.183920611159 -3.72557089791079 0.000236968714161255 FNIP2 other 0.00240244266528266 1 1 1.27439450026484 -3.72557089791079 0.000474431020711055 363.945440021402 193.313670847554 1.8826678859583 0.0608165615716922 -465.833911094387 280.802851397813 -1.65893582908971 0.0982855697814613 MSMO1 other 1 1 1 1.8826678859583 -1.65893582908971 2.53032748198045e-09 250.589952091572 53.7130035858384 4.66534982894981 4.934819815061e-06 -219.298620623132 110.832807643375 -1.97864355587532 0.0489114178382469 TTC17 other 2.67253188646775e-05 1 0.0519488481931472 4.66534982894981 -1.97864355587532 0.307318262299332 22.8633025590859 14.9160079643853 1.53280305385168 0.126521841177009 25.2062836111585 30.7707665581779 0.819163330348023 0.413432098340054 ALX4 other 1 1 1 1.53280305385168 0.819163330348023 0.805664010988014 40.180961218515 61.6956718791454 0.651276823716659 0.515415641460186 39.5548828730251 98.8504971391348 0.400148547734166 0.689360036499305 FSTL4 other 1 1 1 0.651276823716659 0.400148547734166 2.57541474913287e-12 577.795135151996 85.7819465226179 6.73562630103818 9.80524850525744e-11 -89.1868965732392 185.599136201282 -0.480535084368691 0.631236080199858 FOXN3 other 3.12500825659782e-08 1 1.31076562018281e-06 6.73562630103818 -0.480535084368691 0.846439651197312 -1.82640822511886 5.74270863454048 -0.318039507373511 0.750699906938541 -6.10422775546409 10.7622964104417 -0.567186362711744 0.571057085773094 METTL24 other 1 1 1 -0.318039507373511 -0.567186362711744 7.24799949722517e-18 208.293207301017 57.8429775300504 3.60101115460049 0.000376673681914767 -423.9841394125 84.9454887744409 -4.99124962996354 1.07247214548562e-06 AKR7A2 other 1.02464968892272e-13 0.016786334021141 1 3.60101115460049 -4.99124962996354 6.1967221362882e-17 236.80897385127 69.3026245604211 3.4170274986456 0.000729910718723307 -519.105729160351 104.941178208605 -4.94663522958029 1.32422341283643e-06 MRTO4 essential 8.59609294745899e-13 0.0206856939319178 1 3.4170274986456 -4.94663522958029 0.736393794819008 -2.02328290408496 6.89176648590591 -0.293579724185766 0.769305445387088 -19.7355209416193 25.40374464651 -0.776874481153732 0.437915432143343 NNAT other 1 1 1 -0.293579724185766 -0.776874481153732 9.48989888023269e-21 117.117871545195 14.901616378084 7.85940723299265 9.04394343522772e-14 -89.2092455985052 33.1780389973198 -2.68880404913961 0.00761360752211857 USE1 other 1.40070907472235e-16 1 1.29861983786435e-09 7.85940723299265 -2.68880404913961 2.56820589844042e-16 192.170997856058 21.3054418943742 9.01980812267508 4.57444869625181e-17 274.818775078047 228.717090270411 1.20156641881518 0.230641962582451 MCF2L2 other 3.51022382198837e-12 1 6.85069436750671e-13 9.01980812267508 1.20156641881518 0.000544878758910852 12.0661684126135 3.4159601786403 3.53229188327845 0.000484088780731001 -16.9828301256989 16.137792244049 -1.05236390882164 0.293570053692176 NRIP2 other 1 1 1 3.53229188327845 -1.05236390882164 0.360119709098801 383.56001866062 453.224840632808 0.846290812580088 0.398226588700012 -775.705685777944 1072.48907110554 -0.723276074951823 0.470208778201126 LAMA3 other 1 1 1 0.846290812580088 -0.723276074951823 1.96430839109064e-23 177.010162452637 26.3404194082904 6.72009658270381 1.06798428928546e-10 -210.7197602061 48.8791492454696 -4.31103575775986 2.27677656701609e-05 AP5M1 other 2.97651650501965e-19 0.347253962001293 1.42585085475189e-06 6.72009658270381 -4.31103575775986 5.8574729471623e-17 90.557329011921 24.9686649058596 3.62683905420467 0.00034361646540371 -145.941438941549 35.967505387503 -4.05759135556443 6.51532587893813e-05 ANAPC4 essential 8.12958670336656e-13 0.978927713310454 1 3.62683905420467 -4.05759135556443 9.11411461483839e-05 -112.228621433621 63.3058644257999 -1.7727997627323 0.0773810539477553 -386.862889683681 92.7577887294472 -4.17067822533016 4.08778899504628e-05 KCNQ1 other 0.679092679951608 0.618850375960057 1 -1.7727997627323 -4.17067822533016 7.56324993214895e-18 55.3315971250107 51.8820839076604 1.06648756097557 0.287152487086177 -562.040119636351 74.126493011116 -7.58217604537243 5.43269343541262e-13 TRAPPC3 essential 1.06883848041129e-13 8.67275180029271e-09 1 1.06648756097557 -7.58217604537243 1.31816014510595e-09 500.200753654198 134.229216455438 3.72646706032333 0.000236334410404539 -532.663897747973 191.779904083661 -2.77747504512051 0.00586077278911521 THRAP3 other 1.41517673178575e-05 1 1 3.72646706032333 -2.77747504512051 0.000283131921377404 177.901449630935 53.7693092481358 3.30860582214198 0.00106500935110714 -101.174953735839 101.225860614591 -0.999497096113162 0.318448852534555 PHPT1 other 1 1 1 3.30860582214198 -0.999497096113162 0.445898612361701 12.8310843382406 23.6766262449533 0.541930434069997 0.588313377350926 -38.4176208200438 44.5735104580777 -0.861893542268257 0.389510928604968 ENTPD2 other 1 1 1 0.541930434069997 -0.861893542268257 0.516974984435051 -100.539440303387 87.6271412832546 -1.14735501844563 0.252243112450621 -111.884686805283 229.321440984473 -0.487894574205378 0.626017558226903 LY75 other 1 1 1 -1.14735501844563 -0.487894574205378 1.74718934802834e-13 381.245171980346 51.5245396027407 7.39929313138524 1.69511594578641e-12 -314.803355806956 139.552342524757 -2.25580846664117 0.024874304676627 ARID4B other 2.21001980632105e-09 1 2.37604402120882e-08 7.39929313138524 -2.25580846664117 0.621530109977768 28.7322058301677 45.0072556192171 0.638390531368006 0.523760597661304 -80.5800879839584 120.653877929776 -0.667861567042698 0.504792430198346 OPN3 other 1 1 1 0.638390531368006 -0.667861567042698 4.59308543344302e-08 167.374614111225 30.6353932491579 5.46343938691977 1.0578572668589e-07 -149.82208161397 83.2096444038715 -1.80053745797523 0.0728876571153338 SDCCAG8 other 0.000449341547953731 1 0.00124932943216036 5.46343938691977 -1.80053745797523 0.455692917166376 -46.9899991009732 78.9743205864564 -0.595003524589126 0.552339441171257 -146.663184229208 117.173916168272 -1.25167092664708 0.211773094470047 PTPRN other 1 1 1 -0.595003524589126 -1.25167092664708 0.00431651750685293 44.2972180017812 14.8789569763115 2.97717226229673 0.0031732377032106 -46.1825155977196 40.5379014929904 -1.13924287880825 0.255611581929923 HHAT other 1 1 1 2.97717226229673 -1.13924287880825 6.1935359611446e-08 509.430121289533 107.851664938214 4.723433074319 3.72028797933e-06 -85.036130874467 172.787087650193 -0.492144013947516 0.623014508292582 KIF1B other 0.000600587182152192 1 0.0395355003563399 4.723433074319 -0.492144013947516 0.00768821468228899 102.643840201836 70.0242187891894 1.46583342130313 0.143888215170861 -249.137213989117 125.350692393799 -1.98752164213368 0.0479016787553522 FOXC1 other 1 1 1 1.46583342130313 -1.98752164213368 1.17411944499432e-25 207.494772235426 28.8284403337902 7.19757190583143 6.21638316310326e-12 -364.381401107289 62.5349994635114 -5.82683943764807 1.62206833716006e-08 TBC1D22A other 1.80614794223476e-21 0.000257487127840789 8.59290644635763e-08 7.19757190583143 -5.82683943764807 6.00374227967142e-07 766.331306925324 199.846860884684 3.83459266526841 0.000156342762299555 -567.382434108922 371.576107118169 -1.52696156518073 0.127932541888981 SYNE2 other 0.00544299275075011 1 1 3.83459266526841 -1.52696156518073 4.82198935011822e-06 75.763523557484 25.0123661996689 3.02904263245942 0.00269004365819869 -91.9843375672076 45.3514834385678 -2.02825421778778 0.0435123008653925 PLEKHH1 other 0.0405384644664439 1 1 3.02904263245942 -2.02825421778778 6.14640929289313e-08 459.021822398709 93.4513627303838 4.91187938824425 1.56504959325023e-06 -600.105597919668 295.785110671721 -2.02885668097641 0.0434540778526767 ATP9A other 0.000596324629596491 1 0.0171294677981237 4.91187938824425 -2.02885668097641 0.89980233061274 -0.794478209208852 3.93175411349133 -0.202067114645521 0.840015861095967 -4.68923744641674 10.2155546466794 -0.459029157848123 0.646581183564389 CHRDL2 other 1 1 1 -0.202067114645521 -0.459029157848123 1.38229975780818e-06 245.827649762083 60.7401590478597 4.04720128520548 6.80704129761397e-05 -257.726098611879 146.321496823316 -1.76136865879034 0.0793292133234093 FAM168A other 0.0121752962667744 1 0.649527880618325 4.04720128520548 -1.76136865879034 2.64854984655298e-05 61.2978069147296 17.3343136385399 3.53621194313944 0.000479269401554234 -66.8200019304979 41.4081396415631 -1.6136924408801 0.107788768888549 RELT other 0.208732213406841 1 1 3.53621194313944 -1.6136924408801 1.32931529620018e-05 153.996662420475 40.007605771118 3.84918466007398 0.000147887646581063 -71.3154129495183 79.4999189867573 -0.89705013361583 0.370488369050697 GALC other 0.107741004757025 1 1 3.84918466007398 -0.89705013361583 1.1032914302806e-13 626.214689705242 78.7466855473152 7.952267265001 5.14827283200048e-14 89.5141086309753 179.495483558642 0.498698389821773 0.618400937814736 NOP58 essential 1.40448999074721e-09 1 7.41711666906309e-10 7.952267265001 0.498698389821773 3.06055896259343e-31 802.638197195705 128.475498650847 6.24740285598738 1.59524600277115e-09 -1329.13800070324 196.887196108426 -6.75075894712462 8.80928672474383e-11 SZRD1 other 4.80630179485672e-27 1.40446458252591e-06 2.045902998554e-05 6.24740285598738 -6.75075894712462 0.253693770797818 67.8996871687786 54.5007116184772 1.24584955227922 0.213887748738999 -65.3595553408774 137.434586393967 -0.475568465375368 0.634762146271662 KCNH2 other 1 1 1 1.24584955227922 -0.475568465375368 1.60217812036755e-26 503.937271194312 51.460406139758 9.7927184994557 1.48443587309432e-19 -375.339959432048 133.618063505155 -2.8090510338639 0.00533458057467788 CUL1 essential 2.47280171097528e-22 1 2.26703046538965e-15 9.7927184994557 -2.8090510338639 5.66257389872716e-08 55.412448229675 16.8947072403532 3.27987028371357 0.00117391606098997 -80.3064112568027 28.1657301249163 -2.85120999529002 0.00468909714459502 FAM114A2 other 0.000550572060173242 1 1 3.27987028371357 -2.85120999529002 0.0131637239610854 116.498536427588 90.3122372886982 1.28995294464006 0.198162630214666 -253.227120562789 147.372047250797 -1.71828460882984 0.0868826592138489 CYFIP2 other 1 1 1 1.28995294464006 -1.71828460882984 3.3580791028309e-15 499.696945266204 76.1508281727807 6.56193710897573 2.68747682907782e-10 -427.425259030896 139.853734099909 -3.05623058105514 0.00246512275793768 TAB2 other 4.46456616721369e-11 1 3.54048197462712e-06 6.56193710897573 -3.05623058105514 9.60249042935409e-11 210.551460362191 45.5597828457653 4.62143248300758 5.90071163081127e-06 -287.032177204615 83.6721793925119 -3.43043744394571 0.000696560701720058 GINM1 other 1.09362763499914e-06 1 0.061686039388501 4.62143248300758 -3.43043744394571 0.00701122447487659 262.096665682635 83.45059903491 3.14074037470949 0.00187112682397597 212.804306956076 308.495119228009 0.689814177574693 0.49089915752254 EIF2AK2 other 1 1 1 3.14074037470949 0.689814177574693 2.62433888220843e-13 403.396261232115 52.0591222521107 7.74881027149396 1.83353722660829e-13 17.2769464062411 113.525934676149 0.152185017947893 0.879153419186895 USP36 essential 3.30115587992998e-09 1 2.62104146543655e-09 7.74881027149396 0.152185017947893 1.52446825930168e-09 297.98187003421 65.5510666885581 4.54579742309858 8.2914538662797e-06 -384.195022920219 165.340286488718 -2.32366249677712 0.0208918867318783 KMT2C other 1.63148593110465e-05 1 0.0857253415234658 4.54579742309858 -2.32366249677712 0.0656459773973969 69.0152862252711 29.451499668889 2.34335388693891 0.0198291068035691 66.0352894547555 50.5553288713308 1.30619839548118 0.192584548059123 MCOLN3 other 1 1 1 2.34335388693891 1.30619839548118 0.414220137089151 -5.98562062668526 10.720730857691 -0.558322068349587 0.577094121067059 -65.7123329616614 52.7875890895148 -1.24484436768327 0.214284570178449 CCDC85A other 1 1 1 -0.558322068349587 -1.24484436768327 8.48990440385663e-08 579.603175865015 102.592209071545 5.6495827617945 4.07682637990942e-08 -132.780433196393 335.665595642609 -0.395573555705623 0.692732021182712 PUM2 other 0.000816474106518892 1 0.000491420651834281 5.6495827617945 -0.395573555705623 1.41897237338101e-12 436.67709293198 70.6743849336479 6.17871798024066 2.35001299588424e-09 -26.6514305541346 100.877738776237 -0.264195360417938 0.791829450746655 MRPL43 essential 1.73909254081576e-08 1 2.99391655675652e-05 6.17871798024066 -0.264195360417938 0.124044567174393 6.86327960756829 10.1514595744677 0.67608796126523 0.499559246151182 -39.3014435879468 24.3797659155704 -1.6120517204329 0.108110359315906 ITIH4 other 1 1 1 0.67608796126523 -1.6120517204329 2.56692064679148e-11 91.259690698827 21.44685388233 4.25515514767485 2.88064012540383e-05 -66.739824370908 31.267808619411 -2.13445800386139 0.0337027091190002 HPF1 other 2.99456962654695e-07 1 0.284952921204947 4.25515514767485 -2.13445800386139 1.88552141146563e-19 376.979012061038 38.5759326926289 9.77238878615814 1.92005328291497e-19 -234.910617429789 249.82621820276 -0.940296095100533 0.347928518008501 ZFR other 2.73457170304861e-15 1 2.93019331505653e-15 9.77238878615814 -0.940296095100533 0.410766064560346 8.17293285758526 7.63296262333057 1.07074189418984 0.285238185762299 -2.75717614089969 16.5522127340637 -0.166574474675857 0.867829094605527 NPFFR2 other 1 1 1 1.07074189418984 -0.166574474675857 0.200208906213902 6.06235359732292 4.09919253573734 1.47891408965801 0.140316177630067 14.0366982710541 9.19884826077416 1.52591910129766 0.128187675010235 PHF21B other 1 1 1 1.47891408965801 1.52591910129766 0.440289100773432 12.998999591954 58.730541316183 0.221332875547192 0.824999320289762 -118.002779233245 112.324095305994 -1.05055624006391 0.294394923377528 TRAF1 other 1 1 1 0.221332875547192 -1.05055624006391 2.21190128558271e-15 202.953074993513 38.4527239177838 5.27798954964671 2.67270505425413e-07 -300.757463310556 73.4060153253622 -4.09717734953314 5.52332317738637e-05 RC3H2 other 2.95355178663859e-11 0.832199103136804 0.00308269800957671 5.27798954964671 -4.09717734953314 0.57680724944281 14.5365961129906 32.8092832700989 0.443063507158008 0.658071972885889 -63.5914863482581 82.6517476978195 -0.769390704002448 0.442329013713447 IL17RB other 1 1 1 0.443063507158008 -0.769390704002448 2.1760381818795e-06 168.01686356576 53.6571888905577 3.13130201264284 0.00193157723226188 -245.052561816473 94.2837116284597 -2.59909752791811 0.00986083934243007 TRAF3IP2 other 0.0188444906550765 1 1 3.13130201264284 -2.59909752791811 2.13776472501271e-06 306.370926745396 96.5136696687491 3.17437859110436 0.00167478278164937 -1006.86419834374 335.554975494779 -3.00059385756123 0.00294545980724951 DCBLD2 other 0.0185301446364102 1 1 3.17437859110436 -3.00059385756123 0.014492671951544 -1828.09001279399 734.291130743637 -2.48959838442095 0.0133864942619343 -3338.00733391529 1300.40083716387 -2.56690647877109 0.0107963427749407 SERPINB3 other 1 1 1 -2.48959838442095 -2.56690647877109 0.00240879914046064 165.35191384564 47.2802075002664 3.49727555330015 0.000550366542816635 99.7252928162957 146.977642781158 0.678506546500961 0.49803822038277 SOAT1 other 1 1 1 3.49727555330015 0.678506546500961 1.05797040509384e-12 266.387165021157 35.7444294417629 7.452550486368 1.32254439904194e-12 -198.861777150917 225.299082855253 -0.882656842765218 0.378227752851492 PKP2 other 1.30257316275153e-08 1 1.85830713509383e-08 7.452550486368 -0.882656842765218 1.53246562242702e-16 1618.78329185717 263.684755314143 6.13908562870319 2.93954461899917e-09 -922.293844624676 453.549813319647 -2.03350065977135 0.0429761869546565 GDI2 other 2.10514802552799e-12 1 3.73292771166705e-05 6.13908562870319 -2.03350065977135 0.0521045684158283 -142.19325131329 58.6855449875974 -2.42296891582657 0.0160648030391023 -122.542033846101 100.213699034988 -1.2228072112508 0.222488885698579 PRDM1 other 1 1 1 -2.42296891582657 -1.2228072112508 5.61270941012516e-10 157.129809152403 33.7708593578617 4.65282234862123 5.1849055877293e-06 -162.268788537639 57.5751284015436 -2.8183834416475 0.00519188657136757 ATG5 other 6.14816188785109e-06 1 0.0544622482935086 4.65282234862123 -2.8183834416475 3.62389514667594e-20 205.455536870199 50.3556884616481 4.08008594752265 5.92014052826023e-05 -391.020465018279 74.4690433689248 -5.25077867700189 3.05710089929137e-07 PITHD1 other 5.30755683182158e-16 0.00481309965584433 0.568333490712982 4.08008594752265 -5.25077867700189 8.3630853155707e-16 313.9341467177 35.3064971697432 8.89168203824916 8.41742447653816e-17 151.239598096211 142.018238707895 1.0649308108044 0.287848206714998 MTA3 other 1.1291001484552e-11 1 1.25798408801863e-12 8.89168203824916 1.0649308108044 8.56998682493632e-17 120.481130425998 13.0804913646902 9.21074958630592 1.06198672227158e-17 124.730654461247 142.1707950617 0.877329654146732 0.381108317281997 USP13 other 1.18505777815219e-12 1 1.59988299710213e-13 9.21074958630592 0.877329654146732 7.50970952705144e-28 723.167463858271 57.2255379929827 12.6371457433384 8.98857119668839e-29 712.430090024605 613.632226799292 1.16100501067332 0.246721307289471 ATP11B other 1.16670847212271e-23 1 1.41489099207072e-24 12.6371457433384 1.16100501067332 0.060909214222626 -1803.94848293631 1690.86638497504 -1.06687819863599 0.286976351079409 -11386.4994901286 5205.84894847476 -2.18725122507918 0.0295788768712511 LAMC2 other 1 1 1 -1.06687819863599 -2.18725122507918 0.000419790471967362 115.628537469934 30.8519461647007 3.74785230249852 0.000218618762862467 -104.804990901859 139.212387795002 -0.752842419858425 0.452207865193725 CDK14 other 1 1 1 3.74785230249852 -0.752842419858425 1.41477398479311e-10 1583.86774225063 255.043094825624 6.21019652907496 1.98132187587611e-09 -1982.16812428817 967.062951044153 -2.0496784848887 0.0413582526936726 SEC61A1 essential 1.5967139192375e-06 1 2.53212935736967e-05 6.21019652907496 -2.0496784848887 3.11615455202304e-13 293.921365096188 48.9373641567161 6.0060726637205 6.24463583147006e-09 -355.114592607638 110.184633174397 -3.22290488588888 0.00142777615920367 PPP1R12A essential 3.90672296187129e-09 1 7.8207819153331e-05 6.0060726637205 -3.22290488588888 0.821218850570295 25.6277360777249 56.8488012541067 0.450805215103346 0.652487780658014 62.4603507268311 110.16192475383 0.56698674125753 0.571189074582152 RASGRF1 other 1 1 1 0.450805215103346 0.56698674125753 0.655641116573686 0.870483590501376 26.1688387409823 0.0332641275800341 0.973488446394143 -65.3066982723231 75.6939439042324 -0.862773095228713 0.38902510244598 CAMK2B other 1 1 1 0.0332641275800341 -0.862773095228713 0.039681522087314 87.9693333973222 97.4749946592563 0.902481028132774 0.367602827234568 -204.348087100306 146.670666137735 -1.393244419497 0.164687590289932 CROCC other 1 1 1 0.902481028132774 -1.393244419497 0.471786533041888 242.439409188587 200.937379241829 1.20654210830932 0.228656858293176 -69.6735349853566 591.47861915717 -0.117795525871482 0.906316612610406 ATP2B4 other 1 1 1 1.20654210830932 -0.117795525871482 0.000288087681526618 432.38259935261 114.4693837131 3.7772772537704 0.000194780826809251 -421.673465168785 336.951707391944 -1.2514359058531 0.211850690747588 ZC3H11A other 1 1 1 3.7772772537704 -1.2514359058531 9.47488687548628e-24 137.032899446426 15.1777874277146 9.02851618518551 3.22663091783626e-17 -43.0638715863188 26.430699061988 -1.62931262186146 0.10440015633198 RIOK2 essential 1.43904581864886e-19 1 4.83897838747904e-13 9.02851618518551 -1.62931262186146 3.00794202759294e-13 37.9123493280972 27.6579532194207 1.37075759103809 0.171580583869391 -293.434602222951 48.9639074752179 -5.99287551491814 6.52262158160549e-09 YIPF1 other 3.77406486202087e-09 0.000103696637904364 1 1.37075759103809 -5.99287551491814 1.16702641064425e-21 519.934970079395 59.6356648003031 8.71852392055085 2.84156338764557e-16 -81.0335531867182 105.575244499828 -0.767543125953641 0.443424425205896 NDC1 other 1.74003637827058e-17 1 4.22483644475143e-12 8.71852392055085 -0.767543125953641 2.900986094617e-11 79.0426622842641 10.8763021607149 7.26742059169389 4.04316586275857e-12 138.886321815063 101.05302098381 1.37439059676716 0.170472936937155 DGKG other 3.37790820857203e-07 1 5.6183832828893e-08 7.26742059169389 1.37439059676716 5.89872715357681e-06 225.947991218134 74.7305138842634 3.02350378010332 0.00273811715637072 -234.398348213629 135.311493923076 -1.73228704685563 0.0843602432434005 FLYWCH1 other 0.0492012831879842 1 1 3.02350378010332 -1.73228704685563 1.28320279495524e-05 112.376167820778 38.6747531377218 2.90567253061975 0.00396599997567178 -112.507816226137 70.7180448143474 -1.59093505089823 0.112785720708227 UNKL other 0.104080578698819 1 1 2.90567253061975 -1.59093505089823 0.038899057217262 -54.0387964216037 23.5907706955092 -2.29067532888575 0.0227445739686601 -125.226186500753 65.117731960406 -1.9230735274517 0.0555109001765403 TBXAS1 other 1 1 1 -2.29067532888575 -1.9230735274517 0.000114364427149902 65.543417051866 52.6573214895969 1.24471612299564 0.214303585618542 -491.927207644222 145.350289347064 -3.38442537578724 0.000817931720990122 PARP12 other 0.841379090541831 1 1 1.24471612299564 -3.38442537578724 1.49904806337098e-10 562.70616667492 101.480272430348 5.54498084404671 6.95664332889602e-08 -149.531390730905 159.490679971745 -0.937555666308495 0.349304531315968 ALDH18A1 other 1.69032659625712e-06 1 0.000828814486204671 5.54498084404671 -0.937555666308495 0.00196297091435839 239.427408530502 68.7698562778397 3.48157494416133 0.000580864016855931 -66.1535882887387 187.079262352425 -0.353612620965528 0.723904151154626 TARBP1 other 1 1 1 3.48157494416133 -0.353612620965528 8.56732610670384e-27 136.646124763705 16.8992349410403 8.08593556101501 2.06927636536875e-14 -66.6919974795212 25.0606548519672 -2.66122325507732 0.008250430798873 GATB other 1.32467996261855e-22 1 3.00045072978469e-10 8.08593556101501 -2.66122325507732 0.947668972777296 -25.3450963812442 78.5241118347872 -0.322768329230768 0.74711958612883 -28.1711609348783 368.209533506322 -0.0765085049988112 0.939071000157458 MXD1 other 1 1 1 -0.322768329230768 -0.0765085049988112 4.37878406887605e-06 93.011241375649 26.8085858989558 3.46945720024986 0.000606200782574053 -158.639993213626 61.0980891974864 -2.59648043494219 0.00993055564337306 CDK17 other 0.0369963465979337 1 1 3.46945720024986 -2.59648043494219 8.83106688948261e-20 60.6361477987649 9.39924399886656 6.45117286093189 5.0572807478866e-10 -74.8987626666821 18.2119556574247 -4.11261503572502 5.18679177353399e-05 DNAJC25 other 1.28686306713541e-15 0.782583142790808 6.60228001636596e-06 6.45117286093189 -4.11261503572502 0.0116034151611029 747.904666819393 250.734097228133 2.98285983074294 0.0031147677504961 191.250170340754 1156.20624211845 0.165411812680009 0.868742729161567 SLC2A3 other 1 1 1 2.98285983074294 0.165411812680009 0.0472590279223251 33.9542428514661 38.0714217055809 0.891856445867603 0.373258163806686 -70.8359307382873 53.6970975300152 -1.31917615656399 0.188219656979468 PSD other 1 1 1 0.891856445867603 -1.31917615656399 3.07096819764099e-16 186.266042838598 33.9038079899937 5.49395639845448 9.5713633578628e-08 -169.184227607096 51.1989241243412 -3.30444888248466 0.0010892948964175 CTDP1 other 4.19125739614043e-12 1 0.00113277085340306 5.49395639845448 -3.30444888248466 1.00478777570626e-14 2081.69708073874 257.101187798098 8.09680071324095 1.90426545086544e-14 -1241.91751811125 1143.68655561976 -1.08588975887564 0.278489194224949 YBX3 other 1.3179801253939e-10 1 2.76308916920575e-10 8.09680071324095 -1.08588975887564 2.26953336769831e-06 54.1223677563628 10.8589254519114 4.98413659768115 1.10924723111653e-06 -27.9539073110316 48.5577537937981 -0.575683698832912 0.565304961575527 STYK1 other 0.0196125598732496 1 0.0122549634093754 4.98413659768115 -0.575683698832912 2.50194169701842e-12 1111.67937137377 150.578873022388 7.38270481814864 2.04517743077778e-12 -443.195634720711 677.074676121469 -0.654574229920246 0.513313944161728 WNK1 essential 3.03685683184096e-08 1 2.8603851546858e-08 7.38270481814864 -0.654574229920246 4.7964709969289e-06 139.959711665493 77.4071060991388 1.80809900690823 0.071695528958187 -318.786927577511 121.115757063427 -2.63208467095297 0.0089710793287406 CCAR1 essential 0.0403479140261659 1 1 1.80809900690823 -2.63208467095297 6.03921510604866e-07 193.874790050573 44.4758058473158 4.3591068527491 1.8560657482675e-05 -246.052605375168 124.543673679058 -1.97563311011069 0.0492107186798433 OGFR other 0.00547394457212251 1 0.186460365070953 4.3591068527491 -1.97563311011069 0.000189524574380275 -46.5848014332635 109.069544666101 -0.427110992127781 0.669637626233805 -672.586657482558 183.057662937443 -3.67417919954765 0.000287528788229548 GNA15 other 1 1 1 -0.427110992127781 -3.67417919954765 0.0114240731875151 3.38868694870224 20.7345087666956 0.16343222725128 0.870299942635366 -70.6077633304509 29.9581399969899 -2.35688074551843 0.0191408309965632 PIGV other 1 1 1 0.16343222725128 -2.35688074551843 0.000808851711536137 297.774063041834 145.870567867075 2.04135808474525 0.0421802046042267 -330.953225447918 211.73090696521 -1.56308415333194 0.119195484891044 PTPRU other 1 1 1 2.04135808474525 -1.56308415333194 1.10893736088475e-16 246.604688793864 61.5259819900628 4.00813901407853 7.93740075172258e-05 -400.697579275895 88.2317396860198 -4.54142217643913 8.45282781217501e-06 SNRNP40 essential 1.52811568329918e-12 0.130224265274368 0.752624339278335 4.00813901407853 -4.54142217643913 0.471000931769937 29.8810032777541 24.3819119789417 1.2255397896425 0.221435907738505 10.6404446344592 50.8180555439754 0.20938315172747 0.834306455304158 RIMBP2 other 1 1 1 1.2255397896425 0.20938315172747 0.103172112750753 -647.83073818514 338.253809737948 -1.91522081802132 0.0565286207484913 -192.578973049896 479.740982998447 -0.401422809129734 0.688428755050235 COL11A1 other 1 1 1 -1.91522081802132 -0.401422809129734 7.43731233702443e-17 406.346429891627 61.3653468686128 6.62175723966233 1.95390165251801e-10 -384.69405411335 136.601021201767 -2.81618724903336 0.00522364760083081 QSER1 other 1.02999338555451e-12 1 2.5883335190906e-06 6.62175723966233 -2.81618724903336 1.06137694412141e-09 254.570269334489 39.0310674617403 6.52224717102673 3.39790948654677e-10 41.4825271504564 73.2708517494956 0.566153199532609 0.571759893049994 MPC1 other 1.14458889654053e-05 1 4.46111536488725e-06 6.52224717102673 0.566153199532609 4.70856962310058e-19 318.912109374999 37.6884751930494 8.46179389697925 1.62614926331362e-15 -239.466040039061 117.705797874796 -2.03444557840542 0.0428730819956541 ACAA1 other 6.79116996739797e-15 1 2.39401694545031e-11 8.46179389697925 -2.03444557840542 0.463028750420774 88.6346481900367 75.6638685049154 1.17142633520355 0.24247567811607 -83.7531600147288 453.600678910943 -0.184640728968513 0.853651530931401 BCAT1 other 1 1 1 1.17142633520355 -0.184640728968513 0.182942913566979 -93.0662790824204 100.156598268401 -0.929207667706729 0.35361145666992 -462.744083913722 255.069914843883 -1.81418527620925 0.0707590729293422 HDAC7 other 1 1 1 -0.929207667706729 -1.81418527620925 0.000327945120035321 119.347794190324 54.9949404958407 2.17015952948164 0.0308602229496055 -132.195911262424 91.4102974642066 -1.44618182994304 0.149277500782367 LZTS1 other 1 1 1 2.17015952948164 -1.44618182994304 0.296978725544936 -22.0338665175914 15.0559404850113 -1.46346663229221 0.144490146343775 -29.0058851640128 24.4472830892943 -1.18646661300023 0.236469577913886 PRDM6 other 1 1 1 -1.46346663229221 -1.18646661300023 0.0160915175547309 40.971704079735 16.9530500500896 2.41677479619772 0.0163320461163341 -73.6121666793936 72.204637699628 -1.0194936090618 0.308895022483572 SPAG4 other 1 1 1 2.41677479619772 -1.0194936090618 1.78893762022475e-11 1205.87581007748 193.420677254863 6.23447206985292 1.73829041600605e-09 -777.118801953182 494.219380816859 -1.57241668804801 0.117025012138255 NCKAP1 other 2.10253838505015e-07 1 2.22553321961255e-05 6.23447206985292 -1.57241668804801 3.388108466663e-41 655.978462737278 40.535103395482 16.1829724803512 1.01245449249707e-41 197.650598189379 249.23452360619 0.793030577504113 0.428451197690546 MRPS35 essential 5.37862219082752e-37 1 1.60909392492559e-37 16.1829724803512 0.793030577504113 0.000591164095940219 64.9557300980314 41.1289573706286 1.57931866623048 0.115420916016252 -118.687153245847 60.9696726911158 -1.94665885524988 0.0526012430263576 GUCY1B3 other 1 1 1 1.57931866623048 -1.94665885524988 2.58956331821653e-07 139.117914492592 41.6163950056267 3.34286317865309 0.000946008572906244 -314.124640754485 87.4739951034574 -3.59106315406039 0.000390904738089996 SFSWAP essential 0.00241373196890962 1 1 3.34286317865309 -3.59106315406039 7.40006600945748e-13 439.490344100186 55.7898589222368 7.87760271472946 8.20059397524563e-14 332.011114551781 431.255195575892 0.769871570146345 0.442049113306756 TNK2 other 9.16646176591498e-09 1 1.17793331860428e-09 7.87760271472946 0.769871570146345 1.27354855871354e-08 133.996963686609 29.6773684815144 4.5151228206124 9.46120959940681e-06 -220.893453698133 84.1006652496861 -2.62653634239781 0.00911856371865079 MON2 other 0.000128870378656223 1 0.0973463855682967 4.5151228206124 -2.62653634239781 2.34914216439414e-05 2505.51133077156 690.262827057344 3.62979322159473 0.000339012863743713 -899.587595525571 1269.80058053734 -0.708447932150806 0.479276063940636 CDH3 other 0.186099042263304 1 1 3.62979322159473 -0.708447932150806 2.99464172315118e-23 316.356902038628 57.4278979673928 5.50876687526076 8.37423647172778e-08 -544.061243731536 104.844755302031 -5.18920800725068 4.13540542698573e-07 GPBP1 other 4.53119239130006e-19 0.00650333857447776 0.000993603157370501 5.50876687526076 -5.18920800725068 0.00611697762447324 107.229076474592 39.8106982784559 2.69347389298672 0.00751219264443795 -51.7995917182562 94.9078137734295 -0.545788483147613 0.585660320590237 DGAT2 other 1 1 1 2.69347389298672 -0.545788483147613 1.28615661083624e-10 21.1975775200004 4.26571522971082 4.96929034839427 1.18997595053901e-06 -37.9399403298878 12.3249811230723 -3.07829601936382 0.00229463722050407 ZNF112 other 1.45502897383904e-06 1 0.0131242447584947 4.96929034839427 -3.07829601936382 5.95328299974559e-10 719.818470969901 126.903762734258 5.67216019021621 3.60121459568883e-08 -546.639357747326 337.828136223058 -1.61809896552369 0.1068002605228 CS other 6.51348693002165e-06 1 0.000435134759597081 5.67216019021621 -1.61809896552369 0.799198037586265 7.42127844672474 13.6640712913129 0.543123516300951 0.587489558492079 -1.40961306522731 23.8946206041499 -0.0589929042431621 0.953001077327257 LTK other 1 1 1 0.543123516300951 -0.0589929042431621 8.41261723769505e-22 433.915846958797 47.7411808132568 9.08892154670601 2.17894622323945e-17 -372.445129714407 138.091704819976 -2.69708546360512 0.0074333443608103 MRPS24 essential 1.25642438444976e-17 1 3.27386670041727e-13 9.08892154670601 -2.69708546360512 2.16654943453588e-17 215.262409695348 26.4648654877427 8.13389396575803 1.54142141519261e-14 -195.468095227655 87.7788386176767 -2.22682480545251 0.0267870031928932 ELMO2 other 3.03685234238895e-13 1 2.23953117413334e-10 8.13389396575803 -2.22682480545251 7.21578136674306e-17 223.878380849013 56.0687296967741 3.99292764540541 8.42590477212788e-05 -323.598803127627 79.9770002878725 -4.04614829216965 6.80933994750958e-05 WAPL other 9.99602192734916e-13 1 0.796248000966084 3.99292764540541 -4.04614829216965 1.00021964580701e-15 206.644681414941 27.9320323370675 7.39812552560707 1.79504955056719e-12 -154.37674630961 59.951185395435 -2.57504076510496 0.0105617315512365 APPBP2 other 1.3469957970083e-11 1 2.51468491538958e-08 7.39812552560707 -2.57504076510496 1.6720378892184e-11 273.233250659035 54.8851767961257 4.97827039300568 1.14508961273158e-06 -372.849614843437 117.687542350293 -3.16813154049612 0.00171053139815261 POLD1 other 1.96665096529868e-07 1 0.0126394991453312 4.97827039300568 -3.16813154049612 1.65052121241413e-11 1339.45010985042 215.557966684874 6.21387430235215 1.92396811447824e-09 -948.884883179452 580.25604645081 -1.63528650667821 0.103141437215736 EIF4B essential 1.94233336276895e-07 1 2.46075521841767e-05 6.21387430235215 -1.63528650667821 0.0758026419417121 10.6058081622416 4.67617022668379 2.26805433679922 0.0241101905714423 11.2612009438839 9.70535997257113 1.16030739464686 0.246941079138244 SLC6A16 other 1 1 1 2.26805433679922 1.16030739464686 7.98768110427505e-11 35.3695855204343 17.6492164967452 2.00403148360478 0.0460544625892105 -194.12900108377 36.4941441477854 -5.31945619268758 2.17011283879054e-07 BICRA other 9.12832196596553e-07 0.00342161691292104 1 2.00403148360478 -5.31945619268758 2.09179800053337e-10 93.6370776798272 18.9325977928625 4.94581243970269 1.3267828606984e-06 -95.3502447581688 39.420721200447 -2.41878488912799 0.0162267176072385 SPHK2 other 2.34427801919775e-06 1 0.0145839972047968 4.94581243970269 -2.41878488912799 1.54792884957752e-09 2733.00777584595 616.303342772384 4.4345172030899 1.33879302909184e-05 -3388.56730069558 1283.24292926631 -2.64062807081508 0.00875183289046514 RPL18 essential 1.6553551117382e-05 1 0.136088311407186 4.4345172030899 -2.64062807081508 0.121757002462885 9.6666870527795 26.4139145620397 0.365969498011166 0.714671265139888 -93.2684348707377 54.9980289633123 -1.69585049916888 0.0910542170243568 CA11 other 1 1 1 0.365969498011166 -1.69585049916888 4.59912584152499e-10 144.999790024243 40.5829365101757 3.57292503926833 0.000418200673461795 -340.974268425373 90.0318451056525 -3.78726291819566 0.000187918152531902 ISOC2 other 5.0627177263507e-06 1 1 3.57292503926833 -3.78726291819566 8.87405644305968e-10 633.210915671383 128.472957562397 4.92874864629658 1.44604985583628e-06 -621.907628581055 287.242504063944 -2.16509611141187 0.0312563491664067 U2AF2 essential 9.61326534476656e-06 1 0.0158559366692448 4.92874864629658 -2.16509611141187 4.27798336489379e-17 641.234174357577 115.481559451128 5.55269756838492 6.70623509849492e-08 -1171.5043937082 257.879453353728 -4.54283727715706 8.36364990641424e-06 EPN1 other 5.95794743228759e-13 0.128875481407937 0.00079958441079355 5.55269756838492 -4.54283727715706 1.64910068225679e-66 566.717979994288 24.2191281122924 23.3996028827582 6.56763264295494e-67 85.1698451204771 183.326180573036 0.464580917216819 0.642606006137391 MED29 other 2.63097522847248e-62 1 1.04780011185703e-62 23.3996028827582 0.464580917216819 1.43678532190075e-06 42.6762479159338 8.78571246732465 4.85746011773695 2.04003917506016e-06 -79.6868033100328 50.5377618746259 -1.57677745025037 0.116044241593513 AHRR other 0.0126365269061171 1 0.0221364650885778 4.85746011773695 -1.57677745025037 0.00581423393559218 3439.96315263552 1158.69793172265 2.96881789330657 0.00325492792655742 812.85673245066 1861.30840492601 0.436712546023758 0.662665032093225 GPC1 other 1 1 1 2.96881789330657 0.436712546023758 2.05957586430633e-12 56.184599072757 9.49151978419738 5.91945234801068 9.66694373283941e-09 -30.3990775672698 17.8855360543047 -1.69964587446365 0.0903365816099096 ADCK1 other 2.50938723307083e-08 1 0.000120131109767995 5.91945234801068 -1.69964587446365 0.00428641613193177 10.8044433769941 63.2374652347058 0.170855098902105 0.864465669542246 -306.546942210624 115.879472484033 -2.645394698814 0.0086379000611449 HAGH other 1 1 1 0.170855098902105 -2.645394698814 7.27184197828547e-26 311.301620535762 63.6052404348051 4.89427629559617 1.69930244928878e-06 -537.979548480046 99.1232020674344 -5.42738266378898 1.2732455604676e-07 RNF4 essential 1.11957279097683e-21 0.00201070938909044 0.0185325925119434 4.89427629559617 -5.42738266378898 4.86416753389742e-08 100.827253827159 28.951161184627 3.48266700544978 0.000580554177345824 -206.919283169379 62.7731177366735 -3.29630406502004 0.00111342074799873 CASP8 other 0.000474888676334405 1 1 3.48266700544978 -3.29630406502004 0.0365454891931405 442.036400152573 368.795062374954 1.19859630794936 0.231735912326293 -514.119500600703 543.007778255578 -0.946799514092267 0.344587526545443 LIMCH1 other 1 1 1 1.19859630794936 -0.946799514092267 2.23136991818691e-29 285.749289089945 22.2305122914363 12.8539228131068 7.97205575705542e-30 28.788105003549 139.419195847976 0.206485949287355 0.836566961836397 INTS13 other 3.48740804513433e-25 1 1.25679459009979e-25 12.8539228131068 0.206485949287355 2.6309625513862e-12 519.42615606678 69.2444461142828 7.50134032712899 9.06874140428804e-13 -94.2211385492636 434.434846877535 -0.21688209227798 0.828463416587639 TM7SF3 other 3.19083138232118e-08 1 1.27860185059057e-08 7.50134032712899 -0.21688209227798 0.205987887426726 8.87942608149488 13.5101786745325 0.657239722390435 0.511586649145191 -41.8155981635805 30.6689602343921 -1.36345014125026 0.173876454485284 DLX3 other 1 1 1 0.657239722390435 -1.36345014125026 0.000106943274155822 50.1985667056556 14.857782298329 3.37860426931287 0.000834728863238714 -18.3054967053768 26.6372917085176 -0.687213133590581 0.492531801063412 SPA17 other 0.789776079640744 1 1 3.37860426931287 -0.687213133590581 0.086036987118695 -7.8913701356995 4.91072076920629 -1.60696779690346 0.10921738140806 -16.0240414514513 7.22180359477315 -2.21884204425731 0.0273199214146403 TSPAN32 other 1 1 1 -1.60696779690346 -2.21884204425731 0.985910475245209 -4.72273808199081 29.5370193797394 -0.159892168579146 0.873084689141481 -9.53786451915145 100.935354648062 -0.0944947838387031 0.924785698523096 WISP2 other 1 1 1 -0.159892168579146 -0.0944947838387031 9.85008334060461e-07 51.8899556250173 10.2069049747702 5.08380902470248 7.03228551113644e-07 6.16467384587058 32.9842213508866 0.1868976617726 0.851884965152635 DMRT3 other 0.00877248422314247 1 0.00787686300102393 5.08380902470248 0.1868976617726 0.000562783136458597 11.6684203841073 9.61426886532293 1.21365655023373 0.225935581436553 -108.176254953765 33.6782395591036 -3.21205194719044 0.0014769740869172 ST3GAL6 other 1 1 1 1.21365655023373 -3.21205194719044 0.00196293155811341 6.18889161420405 69.3694737653369 0.0892163552391912 0.928975382365094 -341.709487784976 119.534631905665 -2.85866516119486 0.00458226083555676 ATP2C2 other 1 1 1 0.0892163552391912 -2.85866516119486 0.321918716771808 227.8076471065 153.746487397499 1.48170960496497 0.139583687238267 253.026016217802 343.28484400743 0.737073076877013 0.461717913537234 NGFR other 1 1 1 1.48170960496497 0.737073076877013 0.107643976208743 94.2038214313315 51.2304190326232 1.83882590090358 0.067030868481664 -1.16664622611402 92.0898685443438 -0.0126685621833877 0.989901507140251 CDON other 1 1 1 1.83882590090358 -0.0126685621833877 5.27597744174346e-18 214.862316628765 23.1847587410497 9.26739497393783 6.15597694329816e-18 -111.038433295887 98.4755297248898 -1.12757386130437 0.26049726565113 TAF2 essential 7.47553243720631e-14 1 9.29367839129723e-14 9.26739497393783 -1.12757386130437 0.0014514478404716 271.765405908924 98.5284493696901 2.75824300136125 0.00620381889188629 -326.355487401209 271.968611765248 -1.1999748253409 0.231189424202566 HIPK2 ts 1 1 1 2.75824300136125 -1.1999748253409 4.45454834855206e-23 456.583754590786 52.5667370768876 8.68579219446237 3.56088495160188e-16 -464.58137579963 142.097100506281 -3.26946414912312 0.00121624277064871 TNPO3 essential 6.73037709982731e-19 1 5.28720197613846e-12 8.68579219446237 -3.26946414912312 2.46715720498464e-20 293.066879795398 36.412427886965 8.04853992997018 2.619652358318e-14 -185.724011082694 83.8601421431343 -2.21468753017013 0.0276104503547355 RFXANK other 3.62203349263794e-16 1 3.79325661484446e-10 8.04853992997018 -2.21468753017013 2.67653362514085e-23 265.692133745652 33.9611542314112 7.82341294807667 1.14261841798271e-13 -292.002763819095 78.5507652794151 -3.71737643523146 0.000244398882953634 TMEM161A other 4.0514689483757e-19 1 1.63817202586181e-09 7.82341294807667 -3.71737643523146 1.09437717946341e-13 147.955928606868 24.3166448762306 6.0845535788325 4.00259678682977e-09 -125.417797781479 56.0454412459009 -2.23778767716727 0.0260536758572963 LPAR2 other 1.39336102489281e-09 1 5.05568000144468e-05 6.0845535788325 -2.23778767716727 4.93227372886377e-07 603.016928862703 154.429744720727 3.90479780921226 0.00011920924312187 -1348.13759239853 511.978658507072 -2.63319099340916 0.0089462744501767 CTSA other 0.00450809818818149 1 1 3.90479780921226 -2.63319099340916 1.33926730836577e-10 542.473916591504 95.8968749746631 5.65684665673236 3.90061303275191e-08 -266.04715242881 221.80556249166 -1.19946113812549 0.231392483256061 SUGP2 other 1.51310420499165e-06 1 0.000470491944010536 5.65684665673236 -1.19946113812549 0.117314195821818 169.328856601023 135.745638080861 1.24739814107439 0.213324469374409 -182.634760958309 218.46275493191 -0.835999532346976 0.403888956417627 SLC12A2 other 1 1 1 1.24739814107439 -0.835999532346976 7.1927162665526e-08 42.223082847678 19.5647772009949 2.15811723353185 0.0317939093690457 -119.377572593676 31.7580769022476 -3.75896730022804 0.000208835221017321 SNX24 other 0.000695176027162309 1 1 2.15811723353185 -3.75896730022804 0.0018386611181477 152.391995315731 90.9038529168224 1.67640853963771 0.0948242708749301 -770.003580276675 301.294812810837 -2.55564831366715 0.0111514733753246 EYA2 other 1 1 1 1.67640853963771 -2.55564831366715 0.00246763587988004 18.9284148505119 309.211544070009 0.0612150976039441 0.951233027079742 -1581.94727632648 544.22824716103 -2.9067717167911 0.0039536478963243 CNN2 other 1 1 1 0.0612150976039441 -2.9067717167911 0.005183148118919 -59.7511759253211 51.1613365212755 -1.167897087686 0.243874743638098 -288.472363331666 90.0465879471992 -3.20359016269243 0.00151941923476949 ABCA7 other 1 1 1 -1.167897087686 -3.20359016269243 0.0022169884791961 135.730989881942 39.9015132333888 3.40165018524573 0.000770441784480051 52.6451859887591 64.7692183132847 0.812811816473028 0.417036814077785 SNCAIP other 1 1 1 3.40165018524573 0.812811816473028 3.1750635195017e-23 102.394906175576 19.1009371836361 5.36072681623695 1.76596968487177e-07 -120.425590907942 28.0687875697754 -4.29037380430415 2.47861583659563e-05 DDX20 essential 4.80291858595022e-19 0.377567550388613 0.00205770787681259 5.36072681623695 -4.29037380430415 4.88113963611527e-10 294.426652841448 53.3371470788225 5.52010501060996 7.94894503665487e-08 -189.244364323192 103.878437743128 -1.82178677726323 0.0695936936705934 BTBD1 other 5.36730114387235e-06 1 0.000944652628156064 5.52010501060996 -1.82178677726323 4.08978579778313e-17 100.447162311891 10.7725946373305 9.32432396219656 4.10275010960936e-18 101.119732579253 66.2788250909128 1.5256717728558 0.128257813396157 FAR2 other 5.69829855205123e-13 1 6.20499926577319e-14 9.32432396219656 1.5256717728558 0.0544120299405241 -77.3524749984274 46.3184124980885 -1.670015676846 0.096070839625289 -308.164821686898 143.472506557121 -2.14790156721913 0.0326082351440928 BCAS1 other 1 1 1 -1.670015676846 -2.14790156721913 0.754278090742829 54.766017182391 113.074140361603 0.4843372410991 0.628534882033611 124.826570730246 166.162214708702 0.751233190705108 0.453159411884585 CHI3L2 other 1 1 1 0.4843372410991 0.751233190705108 0.0530349245700817 -235.530132416274 141.484753898619 -1.66470326961903 0.0971319424146218 -593.170427628687 246.94242858281 -2.40205958543804 0.0169788414924414 SBNO2 other 1 1 1 -1.66470326961903 -2.40205958543804 1.89048722797749e-09 81.9642578852865 14.2102632060401 5.76796197908899 2.19981666339141e-08 -50.7055194695197 36.0127239853557 -1.40798900661163 0.160288928032188 PMS1 other 2.01374699524162e-05 1 0.000268443627433654 5.76796197908899 -1.40798900661163 1.04573881348782e-13 283.40597572394 74.6977328614649 3.79403717981035 0.000182840337027058 -470.207529215049 125.81218635064 -3.73737666321587 0.000226798170826006 HMG20B other 1.33227124838348e-09 1 1 3.79403717981035 -3.73737666321587 0.717785083859638 10.75593827898 159.833740589225 0.0672945414361724 0.946397212343962 316.911837415792 398.965053560129 0.794334828546655 0.427700738877167 CALCRL other 1 1 1 0.0672945414361724 0.794334828546655 5.00214316366253e-21 265.379965332949 27.4453256337999 9.66940486966289 3.41783663098915e-19 1.91791853242847 52.9436406333784 0.0362256639226906 0.971129091781585 TAF11 other 7.40867423970057e-17 1 5.20844124196437e-15 9.66940486966289 0.0362256639226906 2.67076783017138e-10 258.173579011989 50.6358620352633 5.09863106176003 6.43212778533681e-07 -215.163964321826 97.6795436325502 -2.20275357889905 0.0284540259447885 ANKS1A other 2.97683782350902e-06 1 0.00722392271571177 5.09863106176003 -2.20275357889905 1.06787965497501e-17 655.30831541766 166.612652534238 3.93312455837048 0.000106577570586087 -1436.62547282026 282.941004509252 -5.07747357196254 7.12132325882829e-07 AP3D1 other 1.50453564589429e-13 0.0111712197961239 0.996820017691672 3.93312455837048 -5.07747357196254 1.22977854149958e-08 135.37192340104 29.6012146937299 4.57318812088191 7.30289678753448e-06 -122.053991224246 56.924014687351 -2.14415641438178 0.0329067368708848 ZNF76 other 0.000124564268468493 1 0.0758624918289082 4.57318812088191 -2.14415641438178 0.0771644193367703 -149.029985340972 125.980952802723 -1.18295648687737 0.237866982627785 -524.190124067346 230.853755754325 -2.27065885220074 0.0239555591829544 SLC9A3R2 other 1 1 1 -1.18295648687737 -2.27065885220074 7.63676033446222e-09 86.7803393937378 19.9268301439875 4.35494952115713 1.89163040756622e-05 -47.8707820789954 36.5149133791802 -1.3109926232576 0.190974155916642 NTHL1 other 7.83684345522513e-05 1 0.189862944007421 4.35494952115713 -1.3109926232576 3.67999649606477e-17 295.815630323679 35.4529313067367 8.3438976530403 3.65634528307061e-15 -29.6910270779159 68.3933584107504 -0.434121496119555 0.664544367634568 UHRF1BP1 other 5.13327065724203e-13 1 5.36056781950982e-11 8.3438976530403 -0.434121496119555 1.77392645987815e-21 1386.32644545161 157.249886677558 8.81607277908108 1.56065658983038e-16 -410.65813208158 282.691209075585 -1.45267386780244 0.147488507329821 IPO5 other 2.63924778700672e-17 1 2.32678290977811e-12 8.81607277908108 -1.45267386780244 1.30131769071652e-08 831.964860381212 178.310075676395 4.66583201888768 4.82775170413383e-06 -199.337878629684 248.882979001759 -0.800930137646235 0.423871143507996 OAT other 0.000131628284415976 1 0.050865191954754 4.66583201888768 -0.800930137646235 1.23738910085306e-22 491.741245043237 68.0316453423954 7.22812512571701 5.40492235772122e-12 -323.19582331364 121.080217515863 -2.6692702568964 0.00807816766280616 WDR3 essential 1.86202311896369e-18 1 7.48473648097234e-08 7.22812512571701 -2.6692702568964 4.78355559679079e-22 448.857473644007 54.0495073091913 8.3045617988025 4.76388520072039e-15 -178.825798709219 98.0780037141319 -1.8233017795758 0.0693552009475671 PKN2 other 7.16289615063453e-18 1 6.97528071089479e-11 8.3045617988025 -1.8233017795758 3.38404015082371e-13 182.660949729775 43.0992047405175 4.23815127980902 3.09292646659003e-05 -256.901258173678 75.856820677612 -3.3866599717578 0.000812368582287664 WDR18 essential 4.23986390496703e-09 1 0.304746044753116 4.23815127980902 -3.3866599717578 0.00204743668475324 93.5736763555221 54.0393286705756 1.73158473018694 0.0845069206418529 -305.951228164254 129.092297988078 -2.37001922603089 0.018500895392709 TRAM2 other 1 1 1 1.73158473018694 -2.37001922603089 0.00272073285968752 461.1367688563 135.159565122543 3.41179529867686 0.000743472607507205 211.795908805828 408.585514688787 0.518363723606672 0.604625930547048 NTN1 other 1 1 1 3.41179529867686 0.518363723606672 1.51304672598159e-10 174.002536990621 31.7292099949012 5.48398579789988 9.50246471678873e-08 -27.3036781591643 53.4604148322537 -0.510727016332306 0.609956476905805 MCM10 other 1.70580887887164e-06 1 0.00112499679782062 5.48398579789988 -0.510727016332306 0.0209255920648271 -55.5033627550604 122.839621686976 -0.451835995526719 0.651747221335762 -906.524338582048 328.784497318904 -2.75719915620829 0.00622457883135539 DGKA other 1 1 1 -0.451835995526719 -2.75719915620829 0.000838876403478424 364.567677245805 147.880743884389 2.46528160238915 0.0143083924613746 -757.415394783937 393.670565894545 -1.92398279272632 0.0554001038371367 ERBB3 other 1 1 1 2.46528160238915 -1.92398279272632 0.887530834483635 -3.29086492136947 10.5040571775738 -0.313294650413315 0.754298694465228 -11.6762712247808 26.1842858700586 -0.445926663141594 0.656007598506384 ANKRD44 other 1 1 1 -0.313294650413315 -0.445926663141594 2.95499120720422e-29 1062.78909965205 125.281613955734 8.48320089512544 1.44332463111663e-15 -687.017947880277 214.333544885709 -3.20536828822862 0.00151040731325746 KARS essential 4.61599176477371e-25 1 2.12630584656103e-11 8.48320089512544 -3.20536828822862 2.10195107686553e-18 131.701488589345 20.606955149112 6.39111832079764 7.15872320207036e-10 -84.3619074244526 35.2104311539954 -2.3959350868352 0.0172564942408312 ADAT1 other 2.9996943817948e-14 1 9.29631795020857e-06 6.39111832079764 -2.3959350868352 7.53137074269688e-25 141.120751926174 14.8602835207331 9.4965046749802 1.24082609401385e-18 -78.426024783662 29.0312491785795 -2.70143472990918 0.00734266237002902 TBC1D22B other 1.15214909621777e-20 1 1.88382217593183e-14 9.4965046749802 -2.70143472990918 1.87060850125878e-16 584.14290973818 64.5008192047555 9.05636419723352 2.74032603805217e-17 161.647629091245 248.497058499277 0.650501177227077 0.515919647327874 NDUFB4 essential 2.56366895097516e-12 1 4.11322938311631e-13 9.05636419723352 0.650501177227077 3.39053475810515e-09 565.54867664406 128.762783040622 4.39217500033098 1.60697776872224e-05 -323.013005013271 200.00069943919 -1.61505937688724 0.107452934097584 SPEN other 3.54988989173609e-05 1 0.162256545307884 4.39217500033098 -1.61505937688724 0.879035662503129 56.1711823587455 171.536088662428 0.327459852890122 0.743571989520261 -215.105161350837 670.429139136821 -0.320846975159501 0.748572730654717 MYLK other 1 1 1 0.327459852890122 -0.320846975159501 3.193520117087e-17 486.254299041218 56.5823074945798 8.59375166146764 6.98413074589916e-16 -91.6776004349894 145.602919414551 -0.629641224253003 0.529463754045543 ZC3H15 other 4.46134760357054e-13 1 1.03302277862594e-11 8.59375166146764 -0.629641224253003 7.33885355115854e-28 283.858308686604 24.8766697765617 11.4106233364905 7.37754260739554e-25 -23.610629130609 70.8910284127823 -0.333055249151271 0.739352009044432 MAP2K4 other 1.14038445331452e-23 1 1.15266725697948e-20 11.4106233364905 -0.333055249151271 0.000208115440129944 120.986275175887 29.2095131374978 4.14201615091524 4.59916060681139e-05 93.6541502423846 79.6717902555076 1.17549950794422 0.240822844895251 TMEM206 other 1 1 0.445566679587887 4.14201615091524 1.17549950794422 0.620862486593898 14.5039133882701 21.8504463390813 0.663781103744719 0.507390592114221 -24.6345540882744 52.2303908566437 -0.471651727743886 0.637552123995667 SNAP91 other 1 1 1 0.663781103744719 -0.471651727743886 8.60369477380388e-11 442.566296670428 136.083919664549 3.25215718184315 0.0012892428154077 -694.923941667652 206.03836310795 -3.37278908250479 0.000851829721268229 SLK other 9.8133742590007e-07 1 1 3.25215718184315 -3.37278908250479 0.00076953530428758 91.8155478168924 25.1582032118122 3.64952723546583 0.000314728326063117 1.49355590290161 60.1371142086733 0.0248358425999464 0.980204045493455 CYB5R4 other 1 1 1 3.64952723546583 0.0248358425999464 4.8920653457687e-08 97.2878975505737 47.4248193610842 2.0514131389693 0.041184349375984 -249.979843623496 71.9231341265912 -3.47565281545586 0.000592954447128408 GSTO2 other 0.000477563419053941 1 1 2.0514131389693 -3.47565281545586 3.56725153880783e-11 75.35685843097 18.4658872604402 4.08086854252642 5.91292677618962e-05 -80.3769533811042 31.3040049741228 -2.56762524308143 0.0107785270343936 SEC61A2 other 4.13729833470933e-07 1 0.567700099781965 4.08086854252642 -2.56762524308143 0.000627225789681248 28.7080112070488 15.9707402526378 1.79753791952801 0.0733634028131373 -48.1922840253729 27.4939731271511 -1.75283084050815 0.080761817853075 PRKCQ other 1 1 1 1.79753791952801 -1.75283084050815 0.00719200597110542 -10.9737108053388 58.251365882206 -0.188385467690655 0.850715481705642 242.470417051135 98.1138458927322 2.47131701794901 0.01407675085395 TLE2 other 1 1 1 -0.188385467690655 2.47131701794901 2.7057108172913e-12 87.0538493155379 28.2739726055715 3.07893943769272 0.00228905696713714 -202.24470526448 45.1521111924041 -4.47918602084111 1.10259108465687e-05 ASB1 other 3.28013322380224e-08 0.16953440517684 1 3.07893943769272 -4.47918602084111 5.61704471430309e-06 55.5154739247379 133.254848585677 0.416611286673324 0.677291323254741 -875.57232141323 224.520543844119 -3.89974256440928 0.000121388236235429 FAM107B other 0.0469697279010024 1 1 0.416611286673324 -3.89974256440928 5.45216425234556e-07 1120.40885425645 218.502430808967 5.12767226482715 5.56566927914693e-07 -164.014445823613 522.299049968007 -0.314024017148143 0.753742623319242 ME1 other 0.00496092425320922 1 0.00627417897838233 5.12767226482715 -0.314024017148143 0.000223037616022346 62.6533925104701 70.3551401130775 0.890530420517551 0.373971046790943 -296.885884584233 112.914138461436 -2.62930655655341 0.00904465264179065 TBC1D1 other 1 1 1 0.890530420517551 -2.62930655655341 3.68730366918059e-18 246.131161143995 34.352570914809 7.16485417508854 7.26510397610781e-12 -334.174981099372 86.3711455687215 -3.86905810845688 0.000136702193772986 CDK13 other 5.23781486207103e-14 1 1.0027296507824e-07 7.16485417508854 -3.86905810845688 9.45841790060421e-11 1289.35793514354 182.999409403349 7.04569451533946 1.5363770348797e-11 941.246036044824 788.452588899926 1.19378901064689 0.233608321712911 MTHFD2 other 1.07750296723683e-06 1 2.10314652304682e-07 7.04569451533946 1.19378901064689 3.27316687607389e-14 231.264896737143 28.5243500589669 8.10763071758201 1.7926106330178e-14 -74.9515554961013 133.608694560624 -0.560978129025074 0.575275982641666 FOXJ2 other 4.23580525432722e-10 1 2.60284468197149e-10 8.10763071758201 -0.560978129025074 2.93258870422493e-20 2358.65560391956 337.277305433573 6.99322357573832 2.09621085345031e-11 -2241.73427947237 631.56849021577 -3.5494713783243 0.000454892324347717 YBX1 essential 4.29917504039375e-16 1 2.85734501433811e-07 6.99322357573832 -3.5494713783243 0.0193358687308597 39.628029343553 33.8628059945622 1.17025238103176 0.242923738451484 -118.890348756244 69.2678530324799 -1.71638564718464 0.0872299899049588 PDE4A other 1 1 1 1.17025238103176 -1.71638564718464 0.000197025973259409 368.637838981151 87.9894699238124 4.18956767554508 3.78094155347489e-05 203.137720405847 239.99984386812 0.846407718987814 0.398069368319454 PPP2R5A other 1 1 0.369360180358962 4.18956767554508 0.846407718987814 0.687879371995472 -13.9322985601412 17.4312339573209 -0.799272076449288 0.424851185668359 -27.7787470420727 71.5682034729641 -0.38814369641913 0.698222496401186 CTNNA2 other 1 1 1 -0.799272076449288 -0.38814369641913 6.907821590551e-22 386.940857149818 53.8684893185857 7.18306494287219 6.49553754377388e-12 -461.86175134803 124.155382905972 -3.7200300183345 0.000241802160259595 ELAVL1 other 1.03265024957147e-17 1 8.97423467047799e-08 7.18306494287219 -3.7200300183345 0.894926665648035 -25.5529292964483 66.0093818431834 -0.387110567966742 0.698979302258584 -51.9081183313004 123.505875092068 -0.420288656653825 0.674608880973437 TIE1 other 1 1 1 -0.387110567966742 -0.420288656653825 1.9087215415376e-06 699.201992343343 171.554672466561 4.07568026151913 6.0325855410991e-05 -718.32024856205 433.856975319205 -1.65566140323906 0.0989478813266284 DIP2B other 0.0166287820698756 1 0.578645605102226 4.07568026151913 -1.65566140323906 5.20054979528208e-10 383.617796161316 70.7964623449403 5.41860120484865 1.32009435565416e-07 -360.755052145073 180.729067968373 -1.99610973597343 0.0469151794854363 SMARCD1 other 5.70916356526067e-06 1 0.00155071483958695 5.41860120484865 -1.99610973597343 3.81416210121206e-16 635.442832791665 85.5233691148499 7.4300491125218 1.4329332970065e-12 -178.769579671261 163.56115241403 -1.09298312608322 0.275375429583431 KDM4A other 5.19221886837998e-12 1 2.01198164232683e-08 7.4300491125218 -1.09298312608322 2.01874790168481e-27 387.755303569366 39.3804075719278 9.84640148432024 9.19715856014989e-20 -221.758053996091 78.7642694898208 -2.81546512692217 0.00522688130639544 NFYC other 3.1306742459328e-23 1 1.40642948701812e-15 9.84640148432024 -2.81546512692217 0.0255906686344786 4.48289005733965 3.92922496702671 1.14090949104701 0.25491110579927 -12.8277970878858 7.60005142031734 -1.68785661812669 0.0925849883467968 ZMYND12 other 1 1 1 1.14090949104701 -1.68785661812669 0.0118754276245812 49.59838138795 16.5171250288263 3.00284591303808 0.00293124082619955 33.4831099622193 95.0109094356046 0.352413319282172 0.724809487543622 SLC9A3 other 1 1 1 3.00284591303808 0.352413319282172 0.119103164763677 -4.79510346948939 27.4116929529359 -0.174929125235799 0.861264988923445 -77.1816600712049 41.9140617371752 -1.84142640613495 0.0666438973614096 NGEF other 1 1 1 -0.174929125235799 -1.84142640613495 8.04490586656197e-06 236.613649633661 49.9893958293602 4.73327684217963 3.64552946877743e-06 -128.39169947074 129.600955079592 -0.990669392767131 0.322775225773411 ASPM other 0.0664348326460688 1 0.0387629148415104 4.73327684217963 -0.990669392767131 0.229219754573669 -27.6605644033964 23.7328801404512 -1.16549547462007 0.244839520376549 106.099200947387 89.5175849001532 1.18523305857423 0.236959779251925 CD84 other 1 1 1 -1.16549547462007 1.18523305857423 0.0385816053247269 -131.604058574526 69.3381523407052 -1.89800353963669 0.0587620901132797 -354.19336918955 147.498875574945 -2.4013292834194 0.017012039129008 SPI1 other 1 1 1 -1.89800353963669 -2.4013292834194 5.62404745872576e-15 170.266296319144 22.4126231273844 7.59689284700941 4.85867055162876e-13 -43.7856586655585 42.3202380686173 -1.03462694596767 0.301758782020599 ZNRD1 essential 7.43049150246847e-11 1 6.89396764570604e-09 7.59689284700941 -1.03462694596767 0.163436250199026 47.7863438766184 26.0182599795947 1.83664641348406 0.0673906060436392 19.6810125491859 49.7868508747662 0.395305431120588 0.692937931719498 MPPED2 other 1 1 1 1.83664641348406 0.395305431120588 0.365055135089851 291.099932874644 234.86344807571 1.23944332444956 0.216261609874618 -641.495879482017 1217.07421337995 -0.52708033119896 0.598572203723089 CLDN18 other 1 1 1 1.23944332444956 -0.52708033119896 6.15489736589953e-22 183.015540544883 19.505920112111 9.38256383154417 3.08832962738379e-18 -200.748803425788 71.88159589071 -2.79277054075162 0.00560822646463741 ZBTB11 essential 9.20649547991252e-18 1 4.67356922511989e-14 9.38256383154417 -2.79277054075162 2.1043290236096e-23 188.182538972801 19.451090993001 9.67465213342089 3.22359812741498e-19 -52.2271570507234 41.642670188943 -1.25417406745908 0.210855484307414 ATXN3 other 3.18742717206146e-19 1 4.91340826580591e-15 9.67465213342089 -1.25417406745908 3.05771959315268e-26 425.580410284659 40.0554651548408 10.6247776337014 2.77384481233489e-22 -61.9267092200283 86.8325801135055 -0.713173662916375 0.476349712256169 GOLGA5 other 4.71530938460074e-22 1 4.28947361779468e-18 10.6247776337014 -0.713173662916375 0.458039978783419 197.184919886896 362.455917920876 0.544024556194283 0.586870227403644 -318.876952077144 504.366171238848 -0.632233028820912 0.527765684425364 FGFR2 og 1 1 1 0.544024556194283 -0.632233028820912 3.57790612660261e-19 99.9957493989698 21.7319311099054 4.60132828938483 6.464069371453e-06 -159.565275692378 34.1254089266948 -4.67584948315613 4.62948423423398e-06 LRRC40 other 5.16900098110279e-15 0.0717107107882844 0.0674331716829977 4.60132828938483 -4.67584948315613 2.58373798619738e-15 174.580058854075 27.4192954048902 6.3670512416938 8.16672528676071e-10 -92.9407420229661 44.8316204526972 -2.0731069072337 0.0391038358863994 ISOC1 other 3.44360598800387e-11 1 1.05832592991132e-05 6.3670512416938 -2.0731069072337 0.0124088995772631 86.9361733984527 38.1714431554724 2.27751864251926 0.0235402857340776 -62.54197354818 83.6561934777862 -0.74760721170976 0.455350145546272 EML1 other 1 1 1 2.27751864251926 -0.74760721170976 1.97205836554356e-09 72.4546218807969 13.8815058940931 5.21950733829447 3.58236848251755e-07 -49.9065846418174 25.8262513194418 -1.93239754482866 0.0543563985384379 TRMT11 other 2.09767848342868e-05 1 0.00409536364921406 5.21950733829447 -1.93239754482866 6.33335053907361e-23 256.246089284639 33.445888405505 7.66151241605119 3.3055860163663e-13 -218.383996901511 67.141504961638 -3.25259311697417 0.00128899482544139 THUMPD1 other 9.55639262840817e-19 1 4.70880728031379e-09 7.66151241605119 -3.25259311697417 1.82246717590718e-16 180.548995552829 27.6642566918709 6.52643581079418 3.33477668652232e-10 -151.71997438141 53.4718225455899 -2.83738176779096 0.00489475443709942 MSANTD3 other 2.49860249816874e-12 1 4.38056265541573e-06 6.52643581079418 -2.83738176779096 0.16324162032408 4.16271621710194 19.4441388958322 0.214085912438849 0.830653873282074 -71.1788695636629 44.5490679551582 -1.59776338385596 0.111353750373985 KIF26A other 1 1 1 0.214085912438849 -1.59776338385596 2.94378342199632e-20 221.269865917264 25.5914871311537 8.6462293020831 4.80829047403817e-16 -84.3630236490511 57.7470585572582 -1.46090598823146 0.145203961375288 ATG2B other 4.3152921183044e-16 1 7.13021394395121e-12 8.6462293020831 -1.46090598823146 4.89653382782695e-13 308.202271992929 55.638972902681 5.53932353373976 7.24749656454056e-08 -588.648214172697 178.584343153636 -3.29619161331675 0.00111229455007354 ARFGEF1 other 6.10059149608959e-09 1 0.00086303189090549 5.53932353373976 -3.29619161331675 3.66973014599941e-05 82.9810366815094 18.4342112348891 4.50146934003105 1.00164535623468e-05 -18.6359344333465 77.3683785055675 -0.240872754390289 0.809835200852677 ZFAT other 0.284917848535394 1 0.102828912271052 4.50146934003105 -0.240872754390289 6.74996447108759e-20 334.162294122941 34.5369601999506 9.67549813846728 3.47876673230146e-19 45.612666126661 110.061952675435 0.414427193211532 0.678892789180966 MTFR1 other 9.85494812778789e-16 1 5.30094474668097e-15 9.67549813846728 0.414427193211532 0.0175904737490478 31.5181002291789 12.1298652780763 2.59838831731671 0.00987689858566262 -31.4351258025441 53.4833080789493 -0.587755823857066 0.557183832787741 STAG3 other 1 1 1 2.59838831731671 -0.587755823857066 6.17580814269243e-08 258.686450107194 67.8723196093698 3.8113689291309 0.000171222112792057 -211.728835440389 114.129500614624 -1.85516307615613 0.0646628344852346 FECH other 0.000598929873678312 1 1 3.8113689291309 -1.85516307615613 0.000291902893108807 94.8578326974952 34.7817384424119 2.72723092477253 0.00680850438001975 -114.797341218646 64.6940027786888 -1.77446650829994 0.0771212245668802 MYO9A other 1 1 1 2.72723092477253 -1.77446650829994 1.68921222315374e-05 881.05682745952 289.065981834751 3.0479436627835 0.00254072754024754 -601.577745580721 493.234871384283 -1.21965777458591 0.223695625360768 PFKP other 0.135728202130403 1 1 3.0479436627835 -1.21965777458591 1.47840947953361e-06 497.473946716991 120.112685497072 4.14172695130622 4.67984189074442e-05 -61.2037998855542 204.871511981595 -0.298742364390089 0.765378044537286 IDI1 other 0.0129848704587437 1 0.452961896605152 4.14172695130622 -0.298742364390089 3.76014619335762e-06 51.7896845984579 85.0981448432354 0.608587704160447 0.543307523143675 -521.740782152888 132.584525533372 -3.93515593206663 0.000105728680067205 SP100 other 0.0319161208892195 1 1 0.608587704160447 -3.93515593206663 0.00862846436230162 339.333036024182 376.881643489481 0.900370293661312 0.368746920842429 -1215.32615890031 641.912959896866 -1.89328808549927 0.0594172241131139 KLF6 other 1 1 1 0.900370293661312 -1.89328808549927 0.0345798335937046 36.1909357894925 64.0442212300086 0.565092916963051 0.572478061903967 -210.111481878853 116.07612703948 -1.810117956532 0.0713851062088801 PLPP1 other 1 1 1 0.565092916963051 -1.810117956532 0.0015253203979135 499.040984261404 161.887415751648 3.08264222975172 0.00226575011562085 -166.15419030119 304.613129834362 -0.545459712756107 0.585891066776801 NEO1 other 1 1 1 3.08264222975172 -0.545459712756107 5.60238018692007e-05 815.146735290456 212.502708121388 3.83593575110967 0.000155655452808611 -643.812752832738 676.563288953134 -0.951592797517773 0.342151459904183 TRAM1 other 0.427069441648917 1 1 3.83593575110967 -0.951592797517773 4.48142732804505e-09 668.119169816309 107.132425375556 6.23638611255368 1.71981239491844e-09 -158.520347031417 497.184715639208 -0.318835921630483 0.750097448455638 TNFRSF1A other 4.65754742203722e-05 1 2.20273571541154e-05 6.23638611255368 -0.318835921630483 0.00149596194009063 28.9764961995424 14.6162079601802 1.982490689684 0.0484609552784315 -47.8632314958306 27.9700438296492 -1.71123190894302 0.0882128605476534 CACNB1 other 1 1 1 1.982490689684 -1.71123190894302 0.000416427419740265 58.3956408775984 18.7824535796622 3.10905285243615 0.00207533131105897 -19.2216512702079 33.2309863460751 -0.578425541451862 0.563453712744777 EVI5 other 1 1 1 3.10905285243615 -0.578425541451862 0.00445622551915827 25.1331417753129 19.0659054105809 1.31822440288437 0.188545749561256 -80.8395820932046 35.7104190782969 -2.26375338569844 0.024383068766556 STOML1 other 1 1 1 1.31822440288437 -2.26375338569844 5.85923729266334e-07 11397.9306413797 2224.88796720785 5.12292340530012 5.75924147249177e-07 634.845851622993 4134.82505732133 0.153536326887374 0.878090889782666 PKM essential 0.00531784376682125 1 0.00648720959461473 5.12292340530012 0.153536326887374 4.45734351930742e-27 276.709252423124 32.9282570607971 8.40339808791646 2.47848973850424e-15 -173.962339291884 59.6803970189714 -2.91489916256059 0.0038552212122619 DHX29 other 6.90041350223982e-23 1 3.64189282175813e-11 8.40339808791646 -2.91489916256059 5.06210302529706e-13 534.69596436054 82.796627281876 6.45794378242246 4.84035141801426e-10 -68.8836738607649 133.34672246429 -0.516575680210002 0.605870592563379 DNTTIP2 essential 6.30383689740242e-09 1 6.32246702221023e-06 6.45794378242246 -0.516575680210002 5.60405901935797e-16 107.979596847401 14.0331050920559 7.69463323612735 2.72557972001425e-13 -4.70162365527169 26.9048851494794 -0.174749813245818 0.861408167741253 METTL22 other 7.59518118893585e-12 1 3.88722179668433e-09 7.69463323612735 -0.174749813245818 6.99004818115656e-13 503.412473446124 80.5307858248385 6.25118044347773 1.56893445592127e-09 -162.702202049819 144.094082014112 -1.12913868339079 0.259834174211138 TP53BP1 other 8.66975675908849e-09 1 2.01247222661022e-05 6.25118044347773 -1.12913868339079 1.41379282152538e-10 135.184572116594 20.5937174854538 6.56435984479637 2.62158833876918e-10 -99.5303130503542 56.7934416706389 -1.75249659331369 0.0808110594002596 RRP15 essential 1.5957479576557e-06 1 3.45577774816553e-06 6.56435984479637 -1.75249659331369 0.0204120224834142 657.482126547866 528.398678536618 1.24429176917842 0.214459424901388 -2496.5608773532 1259.17214126833 -1.98270021669833 0.0484031658746567 RHOA other 1 1 1 1.24429176917842 -1.98270021669833 2.9392799325847e-14 287.596529452699 51.8919315746284 5.54222054808447 7.07679843219208e-08 -357.7928118054 103.909053454185 -3.44332663912827 0.000665523636612898 DHX8 essential 3.80842500865e-10 1 0.00084298822924272 5.54222054808447 -3.44332663912827 3.73104856848534e-07 185.51245781685 56.0577702797997 3.30930853815459 0.00106343023401628 -186.566602552748 89.4819767503636 -2.08496290904738 0.0380191653584021 PRKCZ other 0.00344151919957088 1 1 3.30930853815459 -2.08496290904738 3.94701129112e-08 678.515044973892 113.651577428454 5.97013310616853 7.40779710187725e-09 -34.8730800788286 319.469993801659 -0.109159172239754 0.913157026501238 IARS2 essential 0.000387635978900895 1 9.24789390198356e-05 5.97013310616853 -0.109159172239754 0.617743037236668 58.6459140915817 109.472531312158 0.535713510856477 0.592602524990796 -153.009770207733 246.73502866551 -0.620138012163495 0.535695835655052 SYT1 other 1 1 1 0.535713510856477 -0.620138012163495 0.705867066831316 4.28280608162176 13.8730493216739 0.308714110525846 0.757778849635128 -21.9762603360897 33.818615893406 -0.649827314203436 0.51636036806989 NAV3 other 1 1 1 0.308714110525846 -0.649827314203436 5.23397955799191e-12 147.871429391504 34.8650583741763 4.24125001612011 3.04635446626485e-05 -223.095873198113 67.6127925367096 -3.29961039661223 0.00109686943859494 ROGDI other 6.26821391865112e-08 1 0.300401013918377 4.24125001612011 -3.29961039661223 4.73576217406288e-09 346.920362477881 70.3456052141753 4.93165651815266 1.58810437099122e-06 -309.230267655339 151.751224523082 -2.03774479334302 0.0427508831223387 ROCK1 other 4.91666828911208e-05 1 0.0173786261317569 4.93165651815266 -2.03774479334302 1.33234795357691e-18 235.484621104689 53.6317162577023 4.3907716839263 1.62286406925277e-05 -457.86815512273 93.4025203337877 -4.90209636192332 1.63834142565057e-06 CBFB other 1.90725609554534e-14 0.0255548495572977 0.163698298665526 4.3907716839263 -4.90209636192332 0.0126978077584173 -40.5914985590776 159.271958494931 -0.2548565293141 0.79902649731351 -1090.70850144092 377.802575496891 -2.88698005831858 0.00420182888895218 HYAL2 other 1 1 1 -0.2548565293141 -2.88698005831858 0.0351437777490406 95.4480534099144 45.0893611272662 2.11686417868085 0.0351759823358426 -15.4906998038179 72.1069421479311 -0.214829520464728 0.830060626388885 HDAC4 other 1 1 1 2.11686417868085 -0.214829520464728 0.0011444281535467 -13.3123198847264 34.4748356913584 -0.386145999473562 0.699690413497964 -296.662680115275 81.7763643839531 -3.62773134205864 0.000341386919017534 RASSF1 other 1 1 1 -0.386145999473562 -3.62773134205864 2.16204936979972e-72 10533.2444368103 422.610255432556 24.9242518405739 3.4162966375826e-72 7183.99450739291 1145.63316332124 6.27076339739171 1.40584743892759e-09 FGFR3 og 3.45019838432639e-68 2.23839029226051e-05 5.45240943358182e-68 24.9242518405739 6.27076339739171 0.00543061411571151 107.333676219161 48.8463863934479 2.19737188652217 0.0288497605968498 -109.980967302881 91.6702855888494 -1.19974500566254 0.231297933643926 IFI35 other 1 1 1 2.19737188652217 -1.19974500566254 7.45836968411642e-16 153.2203794523 18.2609068484089 8.39062269602727 2.92085566344221e-15 -19.1049246976399 39.4635463369781 -0.484115759250412 0.628703556404509 HEATR6 other 1.00762574432413e-11 1 4.28664777166779e-11 8.39062269602727 -0.484115759250412 2.21569871627647e-11 408.842668717646 71.8586330651938 5.6895414131622 3.3100220947177e-08 -225.501113438837 134.668977479723 -1.67448448528386 0.095193292612098 COASY essential 2.59236749804347e-07 1 0.000400578873902736 5.6895414131622 -1.67448448528386 0.193704993441582 88.0723543282169 51.7408360571852 1.70218266730126 0.0898807121039594 15.0923128443609 96.8196393219696 0.155880696830237 0.876244410391283 PLEKHH3 other 1 1 1 1.70218266730126 0.155880696830237 2.12714105110236e-35 470.089335876623 32.8912696872484 14.2922222324203 5.63441989130048e-35 -60.5494177207929 127.878050889337 -0.473493436126824 0.636239588485373 MEF2A other 3.36215914537239e-31 1 8.93224585367865e-31 14.2922222324203 -0.473493436126824 7.53226595874929e-12 150.328656105732 35.8649190058757 4.1915236468568 3.77510053453534e-05 -116.184267577863 49.9437851034871 -2.32630080673944 0.020754174706694 INPP5A other 8.97243521006215e-08 1 0.368865073229448 4.1915236468568 -2.32630080673944 4.99131803911048e-07 182.448485524194 33.1909813852783 5.49692952450988 8.92143838395662e-08 64.7414967926613 70.7641324543171 0.914891408220912 0.361061961556849 PRR11 other 0.00456006816053134 1 0.00105745809165038 5.49692952450988 0.914891408220912 0.580953924597987 -2.31354479211317 16.4776112864369 -0.140405350745075 0.888445593116479 -71.0973996285183 68.1496571116575 -1.04325395962053 0.297774339977267 REEP1 other 1 1 1 -0.140405350745075 -1.04325395962053 0.00704391008732888 310.188878178095 176.483057464687 1.75761278523952 0.0799680209047112 -550.203033067667 334.515691775694 -1.644774958529 0.101201889091605 ATP11A other 1 1 1 1.75761278523952 -1.644774958529 1.54323541780565e-05 334.912315678604 70.690050648306 4.73775747233292 3.5152383008086e-06 400.806162776481 300.787533886571 1.33252252045667 0.183824637513591 POLR1A essential 0.124400207029314 1 0.0374197117121075 4.73775747233292 1.33252252045667 3.56292018530049e-06 901.420752429593 197.108520580536 4.57322062879206 7.32345789274849e-06 -831.002841414009 644.908122806474 -1.28856004758895 0.198654122253092 LAPTM4A other 0.0302848215750542 1 0.0760467867583003 4.57322062879206 -1.28856004758895 0.0553965734392376 97.7864044750399 48.2859574412691 2.02515202466429 0.0438466802932035 -213.060457206647 199.289493301811 -1.0691003006565 0.28599005324512 TTC7A other 1 1 1 2.02515202466429 -1.0691003006565 2.2847403719768e-05 319.84751142712 89.6761959854785 3.56669356803352 0.000426780160538665 -380.060027650807 213.943021190229 -1.7764544294851 0.0767716793269896 IP6K2 other 0.181385538131238 1 1 3.56669356803352 -1.7764544294851 0.00039934736198486 42.1217244709965 10.5456862682462 3.99421369075124 8.38286516143648e-05 39.5812420627111 52.4665324046763 0.75440933960376 0.451263374437425 STON1-GTF2A1L other 1 1 0.792348415058976 3.99421369075124 0.75440933960376 3.40677502360453e-09 74.5435454545457 11.7530681793831 6.342475370415 9.43139903963278e-10 98.8661079545454 47.2339691870345 2.09311454565803 0.0372686812284297 SRBD1 essential 3.56655277221159e-05 1 1.21957420981491e-05 6.342475370415 2.09311454565803 1.45928438057791e-05 168.825141107746 46.5548732713235 3.62636882553256 0.000343765840490849 -57.1724158327472 74.3001985224029 -0.769478641641969 0.442284355918944 KIF2A other 0.117924770794501 1 1 3.62636882553256 -0.769478641641969 0.638074060894344 -17.6490713373671 18.8115204195055 -0.938205468977775 0.348974233093903 -6.84657448850416 43.2460336657997 -0.158316819096375 0.874325063063113 RASGRP2 other 1 1 1 -0.938205468977775 -0.158316819096375 5.06345758722163e-11 646.360066371684 91.3772409293406 7.07353450156692 1.30665532999831e-11 801.546932422897 436.347894633778 1.83694465420906 0.0673212304836878 PSME4 other 5.84120467261887e-07 1 1.79220845062569e-07 7.07353450156692 1.83694465420906 2.29340945786396e-09 133.063849418074 20.5419068559256 6.47767757644613 4.73987269189799e-10 -96.5260084475004 133.294726368646 -0.724154743980972 0.469631992090486 IFT80 other 2.43032600249844e-05 1 6.19311765923391e-06 6.47767757644613 -0.724154743980972 6.35051953237972e-16 185.76619147517 24.0610067209682 7.72063254166679 2.32984500287803e-13 -364.135248408143 121.807592086577 -2.98942982264462 0.00305556868909973 SIRT2 other 8.59542818707594e-12 1 3.32608672610868e-09 7.72063254166679 -2.98942982264462 6.19710484312979e-11 433.734005957527 61.0384989209249 7.10590878913041 1.0651769743211e-11 413.735488476165 291.460478242175 1.41952518218402 0.156899450023008 ERLEC1 other 7.11613549136594e-07 1 1.46440530429665e-07 7.10590878913041 1.41952518218402 2.75185751128562e-05 81.6085584341659 25.5342774115794 3.1960394695625 0.00155887602284926 -135.369343830838 59.0043706645644 -2.29422570406525 0.0225454002297091 PPP2R5B other 0.216433593262614 1 1 3.1960394695625 -2.29422570406525 0.526409290912689 -0.402863638476399 3.04395474778852 -0.132348760693334 0.894806653124484 7.2019646416453 6.99778468536429 1.0291777991838 0.304313807564372 PYGM other 1 1 1 -0.132348760693334 1.0291777991838 0.0123880944251917 93.207644810347 426.505721070398 0.218537853551939 0.827173346201815 -1724.37698996094 693.759016136001 -2.48555615113318 0.0135337666709942 PITX1 other 1 1 1 0.218537853551939 -2.48555615113318 3.62535329091661e-08 18.7388810770713 101.837643619604 0.184007410335091 0.854144243552524 -815.968201596565 159.61352846753 -5.11214938627559 5.99964974325088e-07 MAST4 other 0.000356771017359103 0.00941945009690387 1 0.184007410335091 -5.11214938627559 0.522596461930605 -208.64078455798 208.850933128385 -0.998993786777693 0.318682337689039 106.792884967165 528.282533371877 0.202151080569589 0.839949175172798 ADGRF5 other 1 1 1 -0.998993786777693 0.202151080569589 0.130303726967646 114.556000342962 95.8167739396637 1.1955735476452 0.232900486158851 -271.350160214591 212.579497062907 -1.27646440020645 0.202876185110044 SDK2 other 1 1 1 1.1955735476452 -1.27646440020645 1.52763771426733e-14 329.700424213943 40.0308106591357 8.23616656233515 7.62447679405148e-15 -110.44480094192 112.807288293486 -0.979057316355131 0.328424856180916 NUP133 essential 1.99326168957602e-10 1 1.11256365378799e-10 8.23616656233515 -0.979057316355131 1.25781450422208e-10 2023.76946920886 306.749894955344 6.59745774160243 2.16334624676654e-10 -1556.98424857657 867.349868678141 -1.79510518742505 0.0737429576871759 NUCKS1 other 1.42409758168024e-06 1 2.86102541134874e-06 6.59745774160243 -1.79510518742505 1.5906956055075e-20 547.803658575316 122.440367407847 4.47404455060632 1.14844229290808e-05 -1131.52587371453 216.718431340009 -5.2211796971679 3.64285970860243e-07 VPS35 essential 2.33975416614099e-16 0.0057313111795442 0.117359317912277 4.47404455060632 -5.2211796971679 6.88698696809722e-22 414.982331706597 69.6190809377027 5.96075567383511 8.14448801220692e-09 -503.685372096456 123.225193876583 -4.08751941263672 5.81495835893154e-05 DNAJA2 other 1.02967342160022e-17 0.875500130520732 0.000101512898584147 5.96075567383511 -4.08751941263672 0.658172655867276 -13.657416810323 55.6938559497646 -0.245223042603513 0.806471406366879 -76.1603803208596 87.5587330115917 -0.869820493071513 0.38517688464878 KCNAB2 other 1 1 1 -0.245223042603513 -0.869820493071513 0.268314205917992 -24.179831314518 17.4430021690786 -1.38621958996152 0.166858429062787 -89.1801347056726 78.9992480442534 -1.1288732097262 0.259983889751322 ABCC9 other 1 1 1 -1.38621958996152 -1.1288732097262 0.0382934488986808 41.2315606827162 16.849705104555 2.4470197209309 0.0150719574641321 -15.8683022861237 72.7289398892904 -0.218184154894582 0.827458104737491 GAL other 1 1 1 2.4470197209309 -0.218184154894582 0.00587582687368319 62.6207605250343 19.5007577533058 3.21119626822802 0.00148182558521891 87.4386083302725 88.4621838957491 0.988429230204367 0.323827422913601 CLEC2D other 1 1 1 3.21119626822802 0.988429230204367 0.00859729770499763 34.8230626871975 47.277745827717 0.736563515826132 0.46202029592363 -230.634973498161 93.470600843546 -2.4674600507191 0.0142212903582846 RORA other 1 1 1 0.736563515826132 -2.4674600507191 0.792834859047644 0.950084581776569 2.49427104616505 0.380906711496862 0.703569801813811 -0.644750453334 4.0066473828087 -0.160920188809334 0.872275714270067 DRD4 other 1 1 1 0.380906711496862 -0.160920188809334 5.31985755096589e-05 310.062898466984 72.2204252057394 4.29328541868434 2.45120357638371e-05 123.939833450344 127.8169668347 0.969666520178262 0.333074188461969 TGFBR3 other 0.406224322591756 1 0.24377219567136 4.29328541868434 0.969666520178262 6.73010930014282e-08 28.0146118315865 5.27931913915463 5.30648197109608 2.31478496557612e-07 4.15472848937054 9.34047202543255 0.444809264248949 0.656810047906294 KIAA1107 other 0.000651541881346826 1 0.00267751176968189 5.30648197109608 0.444809264248949 0.248264889113403 0.188236753939657 3.75468153549365 0.0501338801068008 0.960052631727036 -10.3270463663813 7.32973919732169 -1.40892412245102 0.160003959619351 PLA2G10 other 1 1 1 0.0501338801068008 -1.40892412245102 0.0100619589526077 -28.5975871601301 139.779832690154 -0.204590223136993 0.838047583188013 -583.029898169282 219.753953864526 -2.65310310880098 0.00845164417256228 HES2 other 1 1 1 -0.204590223136993 -2.65310310880098 0.000458368012173694 1224.01285502266 307.716877419569 3.97772415113171 8.96717529550594e-05 810.032338075436 1628.70460364721 0.497347607578136 0.619353257118674 ATP1B3 other 1 1 0.844797584589615 3.97772415113171 0.497347607578136 1.38319871929093e-06 84.1573295197584 21.1239581788558 3.98397538980153 8.73137693216391e-05 -65.3436360969526 40.8102160398693 -1.60115878909133 0.110515427129796 NEDD4 other 0.0121818311207952 1 0.823281530933735 3.98397538980153 -1.60115878909133 8.78838048459746e-11 19.884437180855 11.3028489986387 1.75924115975094 0.079664996428934 -121.821817889401 21.8587675543931 -5.57313295849187 6.03705511187283e-08 PIGB other 1.00213902665865e-06 0.000955363971453876 1 1.75924115975094 -5.57313295849187 7.86393403680948e-09 719.432947916823 141.199220038728 5.09516233672888 6.55489144311406e-07 -329.203656490256 275.381262312066 -1.1954468278862 0.232961398753605 MAPK6 other 8.06446435474813e-05 1 0.00735983211232846 5.09516233672888 -1.1954468278862 4.58016168841211e-10 137.951147124881 30.0364192072344 4.59279603780647 6.70401528316576e-06 -154.05605011741 58.5770476203053 -2.62997293950348 0.00902739205859307 GNB5 other 5.04275801894173e-06 1 0.0698424312200208 4.59279603780647 -2.62997293950348 0.0801818013727982 -61.493908597026 56.2505916773432 -1.09321354253052 0.275270864880792 -244.612357668198 108.783954241998 -2.2486069694069 0.0253411245307452 RAB27A other 1 1 1 -1.09321354253052 -2.2486069694069 1.92215797451808e-17 407.68522765223 50.7449014161545 8.03401359101753 3.34331920891383e-14 -249.928599855283 145.722670584663 -1.71509758126536 0.0875233838521561 HDHD5 other 2.69563434346415e-13 1 4.83209925264316e-10 8.03401359101753 -1.71509758126536 1.33617599485272e-46 904.313937393179 51.500907961182 17.5591843560271 4.18861192725803e-46 175.020956878369 203.707267410224 0.859178757358288 0.391030312618186 UFD1 other 2.12598962541017e-42 1 6.66533815984571e-42 17.5591843560271 0.859178757358288 4.77806769350023e-13 359.363779334626 47.2538709800686 7.6049595912725 4.69924414335002e-13 -114.692832832711 210.875002439525 -0.54389013162242 0.586964248044793 LRP6 other 5.95490576640933e-09 1 6.67057706148535e-09 7.6049595912725 -0.54389013162242 0.903546692763301 4.07472430714384 13.9214025876157 0.292694955231643 0.7699784815897 -15.0785856177989 58.1774731224468 -0.259182546241959 0.795690441838269 GUCY2C other 1 1 1 0.292694955231643 -0.259182546241959 3.86302630059771e-12 311.831979623435 85.2849774039075 3.65635296057601 0.000307050996794783 -352.040748401432 137.428698855601 -2.56162469217094 0.0109578828949735 PHRF1 other 4.65417408696012e-08 1 1 3.65635296057601 -2.56162469217094 5.21332807682827e-09 1496.48848240126 235.450725915774 6.35584569374651 8.78697017427073e-10 1631.13397085074 1509.23257693182 1.08077044968558 0.280763639988556 PFN2 other 5.40205055320945e-05 1 1.13764902846283e-05 6.35584569374651 1.08077044968558 7.40640443856008e-11 185.733315564414 42.8714562349448 4.33233045657595 2.07771457526879e-05 -256.342517933088 83.018047521212 -3.08779266180152 0.00222499207297931 PTPN3 other 8.47737052037586e-07 1 0.207750680381126 4.33233045657595 -3.08779266180152 4.68514796733017e-06 91.1856046159348 60.4018891769368 1.50964822224058 0.132298232954938 -248.495880594017 89.0813262886371 -2.78953952469065 0.00565275154576938 DAPP1 other 0.0394676864767894 1 1 1.50964822224058 -2.78953952469065 0.359310203985226 5.64657970963814 4.88884435313589 1.15499273484054 0.249209537605542 -20.6331065063323 31.5010169178937 -0.654998108794768 0.513078484217101 FGF10 other 1 1 1 1.15499273484054 -0.654998108794768 1.06972441438841e-11 620.525112356532 214.58147385161 2.89179257285578 0.00414225716370338 -2033.7661790423 423.246723543186 -4.80515516343928 2.56869882765557e-06 SLC44A1 other 1.26751645860882e-07 0.0399792285536313 1 2.89179257285578 -4.80515516343928 5.09085256522985e-07 144.463605091756 32.9028422569261 4.3906117278165 1.62190338816244e-05 -37.5836259897557 61.0568462235743 -0.615551380628706 0.538707246168661 TMEM260 other 0.00464743930679833 1 0.163633832831709 4.3906117278165 -0.615551380628706 8.39443506911639e-19 365.991654528373 41.1861081181573 8.88628887872563 9.01285292128591e-17 -268.364139379152 128.796149865127 -2.08363479545141 0.0381304058602709 SMG6 essential 1.20485326547028e-14 1 1.34661035496933e-12 8.88628887872563 -2.08363479545141 1.53436993563097e-21 358.416054142884 50.5374221583908 7.09209213361857 1.15051082367065e-11 -302.996890955882 93.7808226160518 -3.23090459758902 0.00138632790808751 EXOC5 essential 2.28406308618027e-17 1 1.580341667394e-07 7.09209213361857 -3.23090459758902 3.99112842544419e-33 263.985661443279 19.0563244581356 13.8529159714521 4.36837925960733e-33 64.5725131224431 75.143154472876 0.859326622303985 0.390948902360305 CLTCL1 other 6.29041751134259e-29 1 6.91252334040264e-29 13.8529159714521 0.859326622303985 0.0774498718444474 264.909256327655 137.042743526859 1.93304110462248 0.0542766779841062 494.528566628583 241.071504557867 2.05137711126648 0.0411949906353855 FSTL3 other 1 1 1 1.93304110462248 2.05137711126648 1.28422923960387e-35 1212.56901028799 93.5647940777179 12.9596716611249 5.44994832403451e-30 -1252.48635722942 367.268341324377 -3.41027585637501 0.000751794840736494 DGCR2 other 2.03049485073767e-31 1 8.59347851733762e-26 12.9596716611249 -3.41027585637501 4.73502262694034e-19 124.294090138222 45.5467765455253 2.72893274925804 0.00677127023013905 -526.4114584068 80.1212064718974 -6.57018886243856 2.57615266581491e-10 RNF126 other 6.82837613031066e-15 4.10535688824264e-06 1 2.72893274925804 -6.57018886243856 1.0674097727251e-06 172.060024056183 32.6395515873619 5.27151923627545 2.7596144596298e-07 23.1168082877427 100.71197912214 0.229533849788687 0.818626521882458 MNT other 0.00948180101111704 1 0.00317824797315564 5.27151923627545 0.229533849788687 7.5333715961405e-17 221.669010158097 25.7916721103657 8.59459631812735 7.04211476710411e-16 -175.730280266794 98.2925905231073 -1.78782835340454 0.0749334536197767 ZXDC other 1.04314596491758e-12 1 1.04138793175936e-11 8.59459631812735 -1.78782835340454 1.05150860164864e-11 150.485347145507 21.1661972646352 7.10970162774303 1.02593139976506e-11 -10.4532275882197 46.7161758826366 -0.223760344050441 0.823111758444398 JMJD6 essential 1.2464582963943e-07 1 1.41127123351682e-07 7.10970162774303 -0.223760344050441 8.32731162555401e-12 194.221592344969 36.2637370009582 5.35580743760185 2.66762282219319e-07 -239.643270006409 93.5444942785332 -2.56181052508403 0.011260707646948 POLB other 9.90450444743394e-08 1 0.00307710292539985 5.35580743760185 -2.56181052508403 0.907337976586818 23.0862288179752 74.6782375512589 0.309142657553064 0.757449680381954 63.744669320716 164.823262130267 0.386745587345163 0.699246953356188 ST6GALNAC1 other 1 1 1 0.309142657553064 0.386745587345163 1.93064725559506e-08 299.692256246117 50.7604617516316 5.90404905519766 1.0620153293095e-08 -26.9268857784368 114.161487200683 -0.235866634525376 0.813714974985974 WIPI1 other 0.000193277096757621 1 0.000131732381447551 5.90404905519766 -0.235866634525376 4.43789360905689e-35 383.898801124452 37.0027683155796 10.37486703293 2.18879135512088e-21 -389.941038092114 103.638612294304 -3.76250732675573 0.000207115528651691 GBA2 other 7.01054053422717e-31 1 3.37227084083473e-17 10.37486703293 -3.76250732675573 0.000534902264045093 507.184386432265 199.684242010486 2.53993195119338 0.0116442225286916 -483.622020408893 333.179682481896 -1.45153515006178 0.147783290524775 NDST1 other 1 1 1 2.53993195119338 -1.45153515006178 3.5344393923133e-12 767.795145618204 101.0508921268 7.59810358383339 5.18927337242177e-13 1028.26959336935 431.068851000529 2.38539525874507 0.0177638615266152 ASNS other 4.26571490258292e-08 1 7.35787071475682e-09 7.59810358383339 2.38539525874507 6.13227876925836e-13 141.618352110318 31.863278353338 4.44456312812151 1.55453599530314e-05 -336.258573692968 81.7161386999691 -4.11495916281095 5.94036718366573e-05 AP3M2 other 7.61935637080352e-09 0.894025261141692 0.157116953045288 4.44456312812151 -4.11495916281095 0.00191793570726911 66.3229711738707 22.128991591106 2.99710770374764 0.00297635034594041 7.21595349089556 38.6928328680764 0.186493284570257 0.85219645152894 CNGB1 other 1 1 1 2.99710770374764 0.186493284570257 0.043617765862509 256.559786554819 103.609486268091 2.47621907796134 0.0138869803444535 44.5146507279121 230.735678783329 0.192924869541799 0.847161781185425 ST6GALNAC2 other 1 1 1 2.47621907796134 0.192924869541799 3.58716264331693e-07 72.6251605751083 22.5721666039321 3.2174652016992 0.00144980298258032 -88.2640404843911 39.1461606463569 -2.25473045190207 0.0249457582482435 TESK2 other 0.00331489699868918 1 1 3.2174652016992 -2.25473045190207 3.47980672460428e-23 209.388715724804 32.024405076252 6.53841079096511 3.04634898294028e-10 -197.420482550581 56.0638850447422 -3.52134858997068 0.000503022084890722 CFAP20 other 5.26251170961906e-19 1 4.00747208705793e-06 6.53841079096511 -3.52134858997068 1.10927206625583e-24 394.600307178028 65.6290709540762 6.01258407960931 5.8365251594567e-09 -521.818995849079 114.894271440848 -4.54173205770083 8.38047687282961e-06 CSNK2A2 other 1.69496771723892e-20 0.129118007179686 7.31783524492681e-05 6.01258407960931 -4.54173205770083 0.691714431113874 -24.0314092400946 43.750003398672 -0.549289311388352 0.583262607976685 -72.6956874535337 86.9476018592798 -0.836086170279749 0.403848481490944 PTPN21 other 1 1 1 -0.549289311388352 -0.836086170279749 2.70909694894243e-17 92.0745913912895 21.7809460215107 4.227299920782 3.23612857966791e-05 -188.391083892538 37.6875859062976 -4.9987570008048 1.03704681474986e-06 EIF2B3 essential 3.78840117340109e-13 0.0162360049317239 0.318046716809762 4.227299920782 -4.9987570008048 0.214648761439548 0.247346082592434 5.36510583213896 0.0461027406226993 0.963262067431531 -13.6995723018915 8.95318239853518 -1.53013439155813 0.127141348608289 CAMK2A other 1 1 1 0.0461027406226993 -1.53013439155813 3.82275975370837e-11 801.202276326921 114.77242473277 6.98079070989743 2.24442941246865e-11 304.872757177524 191.501540858359 1.59201203191895 0.112543454263432 TCOF1 other 4.42943172662189e-07 1 3.05691285978231e-07 6.98079070989743 1.59201203191895 1.16196946976158e-15 412.763850286243 304.638775121355 1.35492880091123 0.176568624379019 -2789.8478561359 452.553293928406 -6.16468357111828 2.55134138479927e-09 CDC42 essential 1.56273273988236e-11 4.05943927735412e-05 1 1.35492880091123 -6.16468357111828 2.19285849532676e-06 139.98257609868 39.0393858906701 3.5856756684314 0.000398688195962304 -291.230217484632 111.02148943991 -2.62318780763844 0.00920453026179718 OSBPL3 other 0.0189813831355484 1 1 3.5856756684314 -2.62318780763844 2.09039236172076e-25 145.516614420062 12.9115381047582 11.2702772697883 2.11134062787233e-24 -2.58864239209118 36.3111904793935 -0.0712904853273877 0.943219344386715 RAD18 other 3.20979747142223e-21 1 3.29305797729247e-20 11.2702772697883 -0.0712904853273877 2.36016956166376e-07 1220.60574123097 235.800744762509 5.17642869389717 4.41171447210338e-07 -440.828381748132 542.569141356192 -0.812483328200806 0.417227497511263 ATP2B1 other 0.00220557845537478 1 0.00501038412596781 5.17642869389717 -0.812483328200806 0.675171110378394 -5.45537008365748 40.0100398840195 -0.1363500286296 0.891645068411614 -43.6898453051612 58.8395601055791 -0.74252501593768 0.458407708017913 TRPM5 other 1 1 1 -0.1363500286296 -0.74252501593768 0.0146938837859166 193.512877583466 68.0864087367796 2.84216602364184 0.00482018345905711 -8.21414944356092 239.224516477485 -0.0343365703670845 0.972633947023424 NCK2 other 1 1 1 2.84216602364184 -0.0343365703670845 4.96484197381745e-05 578.980442854553 144.887918588456 3.99605742490585 8.29889536535433e-05 -751.697362459285 541.794394623646 -1.38742181520989 0.166448841643421 MAP4K4 other 0.380257246774679 1 0.785075501562519 3.99605742490585 -1.38742181520989 0.857267771878623 22.4254560255354 57.7408490936173 0.388381126664352 0.698038940251768 112.297254742344 246.791976236175 0.455027981277956 0.649453421554594 MGAT4A other 1 1 1 0.388381126664352 0.455027981277956 1.47196330739859e-09 3203.52445430695 485.077702733016 6.60414699801231 2.09225965747069e-10 3344.86372814403 1925.10812216557 1.73749395664144 0.0834319104971924 RPL31 essential 1.57647270222389e-05 1 2.76847797876521e-06 6.60414699801231 1.73749395664144 2.69017794416244e-23 1032.63389063422 316.440517019976 3.26327962158221 0.00124260315760377 -2742.46887981164 459.599532112194 -5.96708370700032 7.53113342889138e-09 WDR1 essential 4.0716855187469e-19 0.000119692303585371 1 3.26327962158221 -5.96708370700032 4.13128462529886e-10 154.998479307389 28.6873915723536 5.40301752135466 1.43962188394397e-07 -204.482101275481 76.9056506562462 -2.65886966081956 0.00830852960245054 SNX13 other 4.56011196940488e-06 1 0.00168651703704036 5.40301752135466 -2.65886966081956 5.54428696413556e-12 80.7398161043034 24.0776039965142 3.35331605736153 0.000913251560343859 -113.063373746426 35.2668199925445 -3.20594183910905 0.00150874972188736 ARHGAP10 other 6.63429378128461e-08 1 1 3.35331605736153 -3.20594183910905 0.0798698947089667 71.4942968189949 116.862250162984 0.611782647683783 0.541196369011794 -414.869916756478 219.379001488951 -1.8911104250667 0.059680013809212 RPS6KA2 other 1 1 1 0.611782647683783 -1.8911104250667 2.39866594419138e-10 45.052614747614 9.29245527562694 4.84830041267801 2.10454547375065e-06 -71.5078825093737 25.4149991006813 -2.8136094841513 0.00525896483820848 ING3 essential 2.68002945944503e-06 1 0.0227922274807195 4.84830041267801 -2.8136094841513 0.425504100348403 -25.6339025895773 45.4131643512654 -0.564459732233193 0.57290646799297 -111.268878045913 85.0261882667181 -1.30864243492692 0.191760129123268 VASH1 other 1 1 1 -0.564459732233193 -1.30864243492692 0.246718471759844 -8.32084280209456 72.8763478802424 -0.114177549288943 0.909181905535942 -329.26293008444 202.833302824362 -1.62331789454494 0.105688386131358 LMCD1 other 1 1 1 -0.114177549288943 -1.62331789454494 5.51811883601611e-16 506.328939951484 65.2918648436616 7.75485492968941 1.81546129470557e-13 -386.943563727261 221.432502638274 -1.74745603792124 0.0816951308308857 BUD23 other 7.48036189410344e-12 1 2.59538346691108e-09 7.75485492968941 -1.74745603792124 5.87979882057218e-07 393.512092026261 114.86632911002 3.42582630676175 0.000707261640295198 -484.173397828724 217.953697729813 -2.22145071577969 0.0271407392830268 SEL1L other 0.00533356551014103 1 1 3.42582630676175 -2.22145071577969 5.87110400147503e-15 276.765899733613 32.1081402502767 8.61980474659311 6.10024675529499e-16 218.353941571643 186.137182890811 1.17308072562659 0.241812820726883 TRIP13 other 7.75161861314749e-11 1 9.02897522251211e-12 8.61980474659311 1.17308072562659 1.1640886351054e-15 602.897213634263 150.927092125348 3.99462551848243 8.36912689278296e-05 -1178.19855699952 265.51915006393 -4.43733929065321 1.3295589455976e-05 TCF3 other 1.56546639648974e-11 0.20406070697032 0.791300947712629 3.99462551848243 -4.43733929065321 0.0161430958410856 264.119075805071 102.351577179698 2.58050811802693 0.0103960143942366 -196.571080868634 322.15729987328 -0.6101711212068 0.5422635753991 TRIB2 other 1 1 1 2.58050811802693 -0.6101711212068 0.000106233208313078 218.692735908847 102.442918577167 2.13477650721277 0.0336797509939597 -357.798488234634 178.650691622342 -2.00278255284341 0.0462002712780885 DAZAP1 other 0.78474470980871 1 1 2.13477650721277 -2.00278255284341 1.77555055751341e-12 361.418006909033 118.728751177615 3.04406475537137 0.00256528896175443 -898.538326842176 208.87407725745 -4.3018182947359 2.37290231436548e-05 MBD3 other 2.16830234083538e-08 0.36163255106505 1 3.04406475537137 -4.3018182947359 7.80286658250492e-07 213.030558400432 43.8979819478602 4.85285539215582 2.07605710387422e-06 -522.729578730471 269.518629937379 -1.93949330646243 0.0534985056047173 HLTF other 0.00700697419108942 1 0.022498230834685 4.85285539215582 -1.93949330646243 0.136680935315799 -6.8721270632201 17.9405802689643 -0.383049319486523 0.701983483803255 -96.8647150420427 49.1323025402191 -1.97150774610554 0.049682933979681 MYO3B other 1 1 1 -0.383049319486523 -1.97150774610554 0.568966788047034 179.442321994591 227.102451617844 0.790138198492662 0.430137910283552 627.778524046278 667.528229764232 0.940452397448429 0.347823070704354 CYBRD1 other 1 1 1 0.790138198492662 0.940452397448429 0.307278186593577 8.37550100673039 14.1951857670594 0.590024050700775 0.555669816236208 -20.9604019374507 23.5092167324671 -0.891582317521603 0.373413649715432 CDH19 other 1 1 1 0.590024050700775 -0.891582317521603 5.51527204987794e-20 404.930808309156 43.033035724798 9.40976627581523 2.26846923511856e-18 -74.418321339313 81.1197594313896 -0.917388338685291 0.359757901539984 PDCD2 essential 8.06057010089661e-16 1 3.43741143197516e-14 9.40976627581523 -0.917388338685291 0.334052725979914 169.083585461088 113.993700114042 1.48327131492296 0.139199686101474 90.953286945234 266.415191415393 0.341396774193031 0.733077503566395 SLC6A15 other 1 1 1 1.48327131492296 0.341396774193031 2.66986464912774e-20 541.048751907619 68.332793461566 7.91784916874404 6.24337872542161e-14 -231.474487557343 123.89845591755 -1.86825966347298 0.0628048854626392 RDH11 other 3.91749239966514e-16 1 8.98234897226406e-10 7.91784916874404 -1.86825966347298 2.85202121803865e-12 197.457094203362 44.6604900328668 4.42129260243334 1.42499765595225e-05 -433.381065821494 112.273541835083 -3.86004626502369 0.000142022730915156 PRKACA other 3.45180128019218e-08 1 0.14445201238388 4.42129260243334 -3.86004626502369 4.5440319896463e-15 572.072817359738 75.169132228405 7.61047520971064 4.62103065371854e-13 -109.907551551028 188.970266688562 -0.581612935606235 0.561314485667399 ADGRL1 other 6.0240232086741e-11 1 6.56093932214958e-09 7.61047520971064 -0.581612935606235 9.39785165882405e-07 2120.59662883845 519.422308539261 4.08260599126379 5.85997175616321e-05 -1105.37283044058 944.807597692031 -1.16994490004185 0.243047251160179 ACTN1 other 0.00837912453900752 1 0.562908886897038 4.08260599126379 -1.16994490004185 2.47136490447585e-14 196.863165842333 35.664448823925 5.51987125370264 7.91204919555598e-08 -188.595256658383 65.0430780011071 -2.89954384777383 0.00404195498316674 ZFYVE26 other 3.2080787825001e-10 1 0.00094066352885965 5.51987125370264 -2.89954384777383 2.18120575986123e-20 334.590191024921 50.4534557535347 6.63166052805968 1.80268268854834e-10 -394.441734759673 130.262083935828 -3.02806252473274 0.00269939378838295 EPN2 other 3.20397314066016e-16 1 2.39107831809051e-06 6.63166052805968 -3.02806252473274 0.113025988505924 121.735043931497 99.8425160277746 1.21927059508028 0.223797776764825 -317.66232762472 270.629780291995 -1.17378925291215 0.24150619451769 PTPN18 other 1 1 1 1.21927059508028 -1.17378925291215 0.892083273725289 13.1243050508648 69.9943424426293 0.187505226749177 0.851404836467346 90.3332296695681 189.408499062859 0.47692278919115 0.633801455807847 LIMS2 other 1 1 1 0.187505226749177 0.47692278919115 8.56034582723105e-21 348.711360650422 36.162004913389 9.64303172585741 8.2751689784652e-19 8.00228955599651 77.6082967711632 0.103111263729858 0.917960770872896 LNX1 other 1.26402066484894e-16 1 1.25774293303693e-14 9.64303172585741 0.103111263729858 1.31456031913111e-10 1484.62852846401 287.790332188333 5.15871578164223 4.83121849525021e-07 -771.099445757248 751.016980367483 -1.02674036128975 0.305465105303127 ALDH3A2 other 1.48624189680963e-06 1 0.00546652372737561 5.15871578164223 -1.02674036128975 4.1073480810541e-27 8625.39705006547 695.989795404071 12.3929935568349 3.46135144963075e-28 5033.63261801118 5369.78152435315 0.937399891444845 0.349396878942947 TFRC essential 6.35899629908797e-23 1 5.44366742483428e-24 12.3929935568349 0.937399891444845 1.02016868353091e-05 1100.06559198182 262.217326256888 4.19524372277413 3.69311891793585e-05 -214.659719067847 662.458392081933 -0.32403502111767 0.746160547813547 SREBF1 other 0.08349060506017 1 0.361371686120023 4.19524372277413 -0.32403502111767 1.72255693011621e-08 332.174488981528 108.12511407346 3.07213076099832 0.00234010980917806 -546.794203292472 173.24102248735 -3.15626284953612 0.00177702268026269 AFF4 og 0.000172944715783667 1 1 3.07213076099832 -3.15626284953612 6.99351600819662e-13 78.7886604707704 30.6770937335885 2.56832218706899 0.0107614634368692 -197.401566179322 45.474959480622 -4.34088492730685 2.01338555930691e-05 UBE2D1 other 8.67335855336545e-09 0.307403707194979 1 2.56832218706899 -4.34088492730685 5.11692861143952e-14 136.309374006719 28.4404261108627 4.79280350707037 2.7140545776125e-06 -180.076898626914 51.6660980702616 -3.48539768538403 0.000572981152264827 MPP5 other 6.5824169657558e-10 1 0.0291679445456015 4.79280350707037 -3.48539768538403 0.00134326886891823 15.3379983973918 29.2979978991043 0.523516946455263 0.601045566107582 -114.487411695357 43.9383611643822 -2.60563682079622 0.00968109830514978 RHOBTB1 other 1 1 1 0.523516946455263 -2.60563682079622 2.33994605799329e-07 169.548979465227 81.7178756119374 2.07480894719269 0.0389444696969647 -746.305723059744 173.644604752446 -4.29789180103641 2.40400880289806e-05 MARK2 other 0.00218738157501212 0.366322861385606 1 2.07480894719269 -4.29789180103641 1.14984734540894e-07 258.454049099707 45.9727847555176 5.62189239729897 4.66337329136075e-08 106.535296368935 74.5621085666449 1.42881281681717 0.15420119776242 HMMR other 0.00109706935225467 1 0.000561190341882353 5.62189239729897 1.42881281681717 0.24917805934055 30.4098029738722 36.4429688175449 0.834449112148952 0.40476837305301 -93.1773525641582 75.25143462106 -1.23821363716674 0.216716375711449 CHFR other 1 1 1 0.834449112148952 -1.23821363716674 0.744414176480642 1.01514126108352 8.85197111126194 0.114679685272809 0.908785208632847 -16.8868190734007 24.5346026931071 -0.688285817570828 0.491870371383874 TRHDE other 1 1 1 0.114679685272809 -0.688285817570828 0.00340981500953674 571.042192025562 176.689822460121 3.2318906888621 0.0013805806374493 185.299071536516 283.097278263248 0.654542045311398 0.513313700872088 P4HA2 other 1 1 1 3.2318906888621 0.654542045311398 0.133419667969876 -51.5485972142202 25.8881927555315 -1.99120107382566 0.0474553163534205 -39.2993767839944 90.7248984512085 -0.433170799360327 0.665232735188627 FCGR2B og 1 1 1 -1.99120107382566 -0.433170799360327 6.63270241076717e-16 80.3806792277647 60.5328844464392 1.32788450381689 0.185333617266237 -737.935384666399 109.176577022823 -6.75909984347772 8.48669002890136e-11 NFATC3 other 8.97139328080368e-12 1.35311785820803e-06 1 1.32788450381689 -6.75909984347772 2.65008837302262e-15 103.945630614864 14.6941818405184 7.07393114792139 1.38261373231549e-11 -103.455733392731 41.2931867444537 -2.50539475272218 0.0128411507124579 TRNT1 essential 3.53150776588994e-11 1 1.89445733601868e-07 7.07393114792139 -2.50539475272218 3.1259778663795e-07 972.291852777572 190.348689646289 5.10795138429536 6.13593610031729e-07 -514.173145231558 569.511408628713 -0.902832037148473 0.367413869585004 ACADVL other 0.00290059486221354 1 0.00690170092563688 5.10795138429536 -0.902832037148473 0.00683108594170535 61.4069935688744 64.7936265302239 0.947732004786463 0.344107128577991 -232.024291983981 105.004092849585 -2.20966902991437 0.0279612266897592 STK10 other 1 1 1 0.947732004786463 -2.20966902991437 2.61343278738703e-11 190.424678363696 43.5130799131755 4.37626292470362 1.72264554373558e-05 -212.769406217288 70.5169895258633 -3.01727863948661 0.00279217513398296 FBXW11 other 3.04830800320823e-07 1 0.173453179798735 4.37626292470362 -3.01727863948661 0.0477305315352253 -65.903708415795 27.7640324146027 -2.3737080922414 0.0183078119457035 -110.772500235605 80.7164935035481 -1.37236511928922 0.171084584092607 ACAP1 other 1 1 1 -2.3737080922414 -1.37236511928922 0.613679054523708 26.9405174885982 144.063534082809 0.187004418988588 0.851797091689843 -138.148243739535 223.041057392376 -0.619384813516659 0.536183248354103 CRMP1 other 1 1 1 0.187004418988588 -0.619384813516659 0.000872493711675821 41.3849139446247 44.9623680566079 0.920434481843146 0.358164358088576 -154.328762291973 69.6113293211772 -2.21700639532283 0.0274527267713101 EVC other 1 1 1 0.920434481843146 -2.21700639532283 7.26673712417728e-16 203.158535863185 25.8086293610424 7.8717289872762 8.34704366359204e-14 -137.383471527731 75.441203812288 -1.82106679884864 0.069695248271705 DERL2 other 9.81881520218835e-12 1 1.19888588140172e-09 7.8717289872762 -1.82106679884864 0.14556281769571 6.11985917280828 13.6218875379713 0.449266605362073 0.653595798451141 -93.9133860501929 52.2584142572372 -1.79709597746141 0.0734255543112952 SIDT1 other 1 1 1 0.449266605362073 -1.79709597746141 0.0974855082110547 -35.3714392288514 32.1319972816008 -1.10081670052629 0.271956865009205 -107.86031764729 50.0190280266371 -2.15638571764829 0.0319366581258204 MRVI1 other 1 1 1 -1.10081670052629 -2.15638571764829 0.00286604525553236 35.6943812645218 10.3237498572165 3.45750156272632 0.000632885816857528 33.8780756661174 22.9631378334965 1.47532431812081 0.1412862316706 TMEM38A other 1 1 1 3.45750156272632 1.47532431812081 5.66312122820793e-10 125.621874569895 35.840703819732 3.50500579457745 0.000533798885765987 -289.8087532502 80.3220675999406 -3.60808382938606 0.000367013795473322 AP1M1 other 6.20168405701051e-06 1 1 3.50500579457745 -3.60808382938606 2.13272030616253e-13 285.143062054612 40.7922865702245 6.99012205564242 2.12144972903521e-11 -171.861775329439 116.970072936965 -1.46927988513827 0.142912520269503 PVR other 2.6912797543465e-09 1 2.89089954575628e-07 6.99012205564242 -1.46927988513827 1.99557117477778e-22 254.067500595688 28.3048116400389 8.97612405363242 4.73655210089907e-17 -216.080264038216 80.8256730047738 -2.67341125666166 0.00796239536028077 XRCC1 other 2.99814613298614e-18 1 7.09203946067617e-13 8.97612405363242 -2.67341125666166 1.85289971409955e-05 427.579247524706 106.867846592741 4.00100929472411 8.14396775215886e-05 -307.717257174278 219.955689811758 -1.39899657716346 0.162957469911983 SCARB1 other 0.148294323766458 1 0.771396625484487 4.00100929472411 -1.39899657716346 0.166763848088336 48.2929680817186 26.2569304208503 1.8392465268282 0.0669892196070784 -2.77953697830433 62.7606938185931 -0.0442878625009859 0.964708050012151 CYP2W1 other 1 1 1 1.8392465268282 -0.0442878625009859 3.6559064800275e-15 1136.99746249862 142.767594842105 7.96397434415062 4.61745400831904e-14 -1030.32210355493 547.282300448402 -1.88261543030125 0.0608237041681113 MCM2 essential 4.85577498677253e-11 1 6.65929217079772e-10 7.96397434415062 -1.88261543030125 0.00161568195251075 12.7165419038247 5.08276844350384 2.50189282576456 0.0129518941169979 -14.0556458583629 10.8483195054675 -1.2956519073096 0.196214428382705 MOV10L1 other 1 1 1 2.50189282576456 -1.2956519073096 9.64811800237692e-07 365.253983921912 78.2573213248532 4.66734585005421 4.84162140926704e-06 -77.9305415340467 166.889474263256 -0.466958997133138 0.640911463888743 PANX2 other 0.00859743795191808 1 0.0509967983038097 4.66734585005421 -0.466958997133138 8.23368990608202e-12 154.157832382131 28.8972286785986 5.33469261349275 2.04852904298474e-07 -153.345411077588 61.6254584260198 -2.4883451578973 0.0134463080435176 SELENOO other 9.79562088126578e-08 1 0.00237793251309669 5.33469261349275 -2.4883451578973 4.82767220284914e-08 2137.08681945429 356.526815040594 5.99418256719614 6.77204525955988e-09 966.044468699062 2942.15265041797 0.32834614089851 0.742913229365261 TP63 other 0.000471518744052275 1 8.46641098350176e-05 5.99418256719614 0.32834614089851 6.92127026408203e-15 25.7814739121814 31.3218955392066 0.823113463229258 0.41117257025979 -311.76091021398 48.6032928438135 -6.414398942389 6.33405703887029e-10 ALPK1 other 9.11738931887525e-11 1.00907862686243e-05 1 0.823113463229258 -6.414398942389 0.0885312133159037 159.855592115114 73.9453763844992 2.16180645675398 0.031508544453957 13.5480198335284 171.252002367726 0.0791115995504508 0.937002242070218 LLGL2 other 1 1 1 2.16180645675398 0.0791115995504508 3.74687779891302e-07 119.082962257371 23.7183165471624 5.0207173017774 9.4212650498836e-07 -38.5166999119998 47.5377204182266 -0.810234474289852 0.418526977494591 PDE8A other 0.00345537070615759 1 0.0104698518499356 5.0207173017774 -0.810234474289852 1.16753584772576e-23 211.439540860591 24.5343874477515 8.61808925577917 5.67060676175563e-16 -112.615700214004 47.9228857121732 -2.34993570484003 0.0194915824331766 NLE1 essential 1.77220266326293e-19 1 8.3981686141601e-12 8.61808925577917 -2.34993570484003 1.31900032580863e-23 649.946974624104 57.134647282899 11.3757064326647 1.15214495381071e-24 353.240354558943 328.653732968472 1.07481010901169 0.283441088351535 SDHA ts 2.00118729431686e-19 1 1.79849827289852e-20 11.3757064326647 1.07481010901169 4.46338320195291e-14 549.673414118525 86.3254699819311 6.36745347848761 8.47928291477298e-10 -451.387112597239 192.643172997785 -2.34312540420225 0.0198656354352637 SMARCE1 other 5.75285460899711e-10 1 1.09832151595054e-05 6.36745347848761 -2.34312540420225 2.7979693004427e-09 9.4010761787168 2.36706372684036 3.97161938316959 9.1459252376591e-05 -12.0944029653697 4.62357271794032 -2.6158132905407 0.00939873183852094 FNDC8 other 2.94877984573656e-05 1 0.861271779630357 3.97161938316959 -2.6158132905407 2.26983420249424e-30 191.886299423155 14.8370078532991 12.9329512608223 5.18511977049686e-30 -0.210661838486514 66.0033359443278 -0.003191684715212 0.997455800665832 GSDMB other 3.55864606267047e-26 1 8.17693387807355e-26 12.9329512608223 -0.003191684715212 1.00724124046409e-25 537.856991672704 46.6955938158771 11.5183671031896 4.13343722637571e-25 -222.030417280732 209.810587832373 -1.05824219632864 0.290919729364812 KDM5A other 1.55004354495018e-21 1 6.46180241599315e-21 11.5183671031896 -1.05824219632864 0.000114894475462132 21.756617029738 5.64408978738639 3.85476097108881 0.000144501361109032 -4.63180961218386 11.8063196098364 -0.392316129433333 0.695130758031493 ADAM11 other 0.844589289122135 1 1 3.85476097108881 -0.392316129433333 8.07461362102195e-15 186.236036041705 21.9387283497602 8.48891663512212 1.40692787106559e-15 14.2958087675474 110.697893852719 0.129142554297985 0.897340999091683 PPP2R3A other 1.06140796048333e-10 1 2.07282683244093e-11 8.48891663512212 0.129142554297985 0.573116932891566 45.0117656559723 76.3114114334524 0.589843180861947 0.5557909035758 -75.3369150576316 145.45132885207 -0.517952745101781 0.604916957345578 FERMT2 other 1 1 1 0.589843180861947 -0.517952745101781 0.107751012942624 -17.2255590011426 68.0572241943935 -0.2531040489095 0.800378296128259 -354.433708720961 172.870945906413 -2.05027922339732 0.0412921231019442 DHRS9 other 1 1 1 -0.2531040489095 -2.05027922339732 0.00960656969334858 -447.421035302654 218.941376294508 -2.04356546430405 0.0419928851381598 -1595.52379814043 679.459776636048 -2.34822406418191 0.0196042171571278 PTGS2 other 1 1 1 -2.04356546430405 -2.34822406418191 7.45263990030017e-22 512.050882555803 47.437293438307 10.7942685056797 8.60206003327452e-23 136.005240697763 457.70512112832 0.297145988584281 0.766585237164138 IGF2BP2 other 1.11364798030186e-17 1 1.33314726395689e-18 10.7942685056797 0.297145988584281 6.10580894674114e-21 296.889983957548 28.7756212516966 10.3174135272594 3.10508548847322e-21 -337.703090446543 299.0197843488 -1.12936704566886 0.25975287390435 MAP3K13 other 9.0317125940195e-17 1 4.78090012660221e-17 10.3174135272594 -1.12936704566886 0.888942435086571 -30.786552712462 63.9482755903644 -0.481428974092631 0.630605973530179 -60.3015048806093 570.367600823611 -0.105723931011393 0.915880777200434 ST6GAL1 other 1 1 1 -0.481428974092631 -0.105723931011393 0.362788452817215 -4.60983876877977 3.32267199399662 -1.3873890582967 0.166467218643653 -1.10865814946415 7.02545880568316 -0.15780580032258 0.874727780878996 TBX21 other 1 1 1 -1.3873890582967 -0.15780580032258 0.434157646035929 60.4947045422034 75.0965994704227 0.805558506893906 0.421203705934559 -52.4207260452578 116.561674862483 -0.449725230073284 0.653268075213815 FRY other 1 1 1 0.805558506893906 -0.449725230073284 3.6536736190253e-13 678.024205670447 139.1379205392 4.87303678999158 1.87967498653869e-06 -952.488467319755 285.835817458015 -3.3322922081298 0.000982125388637771 PICALM other 4.57293790157206e-09 1 0.0204489841785544 4.87303678999158 -3.3322922081298 6.53218193605058e-10 226.373327435585 54.7716347836057 4.13303945244561 4.79620524713351e-05 -440.195278887178 118.739041106734 -3.70724973676928 0.000254770205274914 NSF essential 7.13444911055445e-06 1 0.463601199187925 4.13303945244561 -3.70724973676928 0.0159340148889624 149.703944738965 61.9098548272512 2.4180955545234 0.016261695906691 -147.089326920902 184.482018344747 -0.797309831281395 0.425969126343574 GLI2 other 1 1 1 2.4180955545234 -0.797309831281395 8.47333144398096e-05 315.300344130165 103.499925086509 3.04638234150049 0.00254451675747702 -651.762289824012 308.434407592165 -2.11313094058501 0.0355037876794752 CLASP1 other 0.633466258752017 1 1 3.04638234150049 -2.11313094058501 2.65940550875576e-15 341.340869106364 60.8225879752889 5.61207407427392 4.95266360684947e-08 -258.305999789405 111.454331439934 -2.31759498668399 0.0212192522669188 MRPS34 essential 3.5431259593153e-11 1 0.000595359692179375 5.61207407427392 -2.31759498668399 1.30369754922073e-07 1581.47970251541 512.361085087162 3.08665070112882 0.00223326256443712 -3504.23054959991 1157.95193152781 -3.02623144725568 0.00271344820280009 NOTCH3 other 0.0012391645205343 1 1 3.08665070112882 -3.02623144725568 1.83264250548221e-37 941.339281530022 67.3068740004696 13.9857822177784 7.88363306914548e-34 -49.628096464907 170.034467979681 -0.291870801576758 0.770608711312252 CLNS1A essential 2.90308899293436e-33 1 1.24860980549126e-29 13.9857822177784 -0.291870801576758 0.0120511386751489 19.902175602174 146.509345035542 0.135842362801812 0.892046750828953 -491.486948741496 224.135809311243 -2.19280868260993 0.0291712819980219 PPP2R2C other 1 1 1 0.135842362801812 -2.19280868260993 2.08781976614199e-05 277.115213730338 82.0774731414196 3.37626395068069 0.000841981253929228 -280.660732840917 170.351245540827 -1.64754141920056 0.100601496370421 TEAD2 other 0.166232209780225 1 1 3.37626395068069 -1.64754141920056 3.03733457475657e-07 5.69734868225942 3.86344460611981 1.47468108465556 0.141450567029754 -26.6085232033492 6.43107148479451 -4.13749454756674 4.68044945671304e-05 CDHR2 other 0.0028210763530339 0.707215912909341 1 1.47468108465556 -4.13749454756674 0.00257349863847507 11.5079571205216 3.34462537492473 3.4407312719681 0.000670966370924197 5.93799291100754 5.56744746435005 1.06655571498971 0.287114804055936 SNCB other 1 1 1 3.4407312719681 1.06655571498971 1.41050022888721e-27 411.585234718948 51.896857846675 7.93083149532757 5.67593380787512e-14 -365.751519403032 99.0458905169171 -3.69274805339411 0.00026807494393302 TSG101 essential 2.18867320516429e-23 1 8.17107430981703e-10 7.93083149532757 -3.69274805339411 1.55554404147238e-20 353.562655451544 36.7925966628055 9.60961409415738 5.06788043967973e-19 -125.633021299688 110.377789988417 -1.1382092476473 0.256030995281544 NCBP3 other 2.28867194821831e-16 1 7.71432760528048e-15 9.60961409415738 -1.1382092476473 0.195614510945228 -106.873185483871 100.465630541846 -1.06377857688711 0.288369038326154 -515.826542776996 302.58297239106 -1.70474411927694 0.089379806908994 ATP2A3 other 1 1 1 -1.06377857688711 -1.70474411927694 0.600635389265674 367.043958343394 464.29271415311 0.790544299220586 0.429896154196271 -245.567384466285 921.120038121109 -0.266596506756264 0.78998110072096 CA12 other 1 1 1 0.790544299220586 -0.266596506756264 0.25338822280827 46.2507583836521 119.026281884673 0.388576015744702 0.697894913140435 -682.276712758138 451.013270941994 -1.51276416175764 0.131504863381461 MGLL other 1 1 1 0.388576015744702 -1.51276416175764 0.229579694503535 -71.8385676108059 88.7167288448409 -0.809752214111121 0.418790420010479 -344.986760535215 204.455911022121 -1.68734060468366 0.0926842364834935 NTN4 other 1 1 1 -0.809752214111121 -1.68734060468366 1.13908368177974e-16 98.772503277334 26.5135907995391 3.72535368838274 0.000237495659499523 -198.110559721026 39.4621831081251 -5.02026355658555 9.38202209458343e-07 BCS1L essential 1.56931558838795e-12 0.0146959994089555 1 3.72535368838274 -5.02026355658555 0.154290825992845 54.734934302427 124.717976911295 0.438869645402898 0.661105682621826 -450.160187852862 270.076313655444 -1.66678884852955 0.0967116595958773 NUAK1 other 1 1 1 0.438869645402898 -1.66678884852955 6.48480966533962e-13 174.729785666545 29.0322350956756 6.0184751566913 5.6970803518514e-09 -129.115252967149 58.437972925511 -2.20944099364514 0.0279803439526886 DPP8 other 8.05283664241874e-09 1 7.14698730139759e-05 6.0184751566913 -2.20944099364514 6.35933133783891e-11 104.407105861975 16.8594643238304 6.19278903864096 2.19254528305222e-09 -25.3597133541643 33.9502247792246 -0.746967465431416 0.455733170602144 SLC24A1 other 7.30114830897286e-07 1 2.79703001758971e-05 6.19278903864096 -0.746967465431416 9.18042071392157e-09 394.861584449214 125.935688693457 3.13542244097586 0.00190487784577354 -619.340895543138 210.98079860233 -2.93553204673621 0.00361532035300673 ZNF532 other 9.37504563305671e-05 1 1 3.13542244097586 -2.93553204673621 0.0824106117047674 -46.2021488871833 24.2777030150957 -1.90306920133487 0.0580911316248619 -123.637950384228 75.1945704132488 -1.64424039800677 0.101286064898931 SCARF1 other 1 1 1 -1.90306920133487 -1.64424039800677 2.57559877159574e-17 1277.31323912569 209.668734635208 6.09205393139813 3.79331794588147e-09 -1109.94788677471 358.60769816922 -3.09515911800352 0.00217231617769472 LMAN1 other 3.60403536109392e-13 1 4.79665054256712e-05 6.09205393139813 -3.09515911800352 1.2731730899518e-11 931.939675315852 154.4516129606 6.03386172181696 5.25984125163903e-09 -460.028854775172 311.022158047714 -1.47908707746989 0.14028276954788 HACD3 other 1.50501790963202e-07 1 6.60951651680961e-05 6.03386172181696 -1.47908707746989 6.75883398690634e-07 82.4333622382644 15.8794855357725 5.19118595199841 4.09563504276921e-07 0.480634687265539 30.1939549544263 0.0159182421776476 0.987311286420048 IPCEF1 other 0.00610187532337904 1 0.00466451875020985 5.19118595199841 0.0159182421776476 8.67222886716865e-10 302.199043104595 48.8851053481584 6.18182247848994 2.29982535140008e-09 -119.675110125794 148.000300741031 -0.808613965826999 0.419441330388751 ZZEF1 other 9.40243053778425e-06 1 2.9311274103594e-05 6.18182247848994 -0.808613965826999 4.63805931093779e-19 23011.1964503016 2791.51805146975 8.24325547104598 7.10036742385206e-15 -1702.75165397751 4465.04181672834 -0.381351782103838 0.70323885949438 ENO1 essential 6.69040055602777e-15 1 1.03686665490512e-10 8.24325547104598 -0.381351782103838 9.05029066062637e-05 266.26990471541 84.2387688035498 3.16089501897123 0.00174999638501019 -105.806937555031 155.258545502635 -0.681488656308683 0.496140036848848 MYDGF other 0.67460866584309 1 1 3.16089501897123 -0.681488656308683 0.016411242689579 17.2222752040914 18.3867592022305 0.936667251399157 0.349760641795558 -82.9721797973842 40.9376136365397 -2.02679571247225 0.0436587388958276 ANO8 other 1 1 1 0.936667251399157 -2.02679571247225 1.08701062118359e-09 95.3071013657119 19.2888816061944 4.9410382266593 1.36223617830372e-06 -80.4727930570562 35.016816386972 -2.29811848592255 0.0223167528486514 TUBE1 essential 1.17179744963591e-05 1 0.0149674595381712 4.9410382266593 -2.29811848592255 3.77204111721349e-06 91.9785674129022 59.4901934201519 1.54611310074754 0.123235660216201 -273.598809743572 89.3734490094232 -3.06129854868558 0.00242349670145138 ARHGEF10L other 0.0320095409206737 1 1 1.54611310074754 -3.06129854868558 0.243049768848488 -0.821003202757112 3.24831290611154 -0.252747572813086 0.800667706246727 -7.8904446982413 5.3462935804867 -1.47587194370329 0.141216853071947 TXK other 1 1 1 -0.252747572813086 -1.47587194370329 0.00793699057600398 76.2027163408078 29.4990239273307 2.5832283986253 0.0103144268285345 -56.0090829783962 62.7839068873382 -0.892092986167633 0.373137439324067 WSCD2 other 1 1 1 2.5832283986253 -0.892092986167633 0.00368188295550526 14.9823391539221 14.7513595020715 1.01565819420361 0.310694759550847 139.632211192989 41.3049050427552 3.38052371863472 0.000829559777432566 KCNQ2 other 1 1 1 1.01565819420361 3.38052371863472 0.00745970778113684 2.15177955142399 2.56886036682147 0.837639748433056 0.402968468795864 -7.56548850982483 4.03797643719568 -1.87358411508685 0.0620599492098896 TACR2 other 1 1 1 0.837639748433056 -1.87358411508685 4.54239227867131e-07 168.024026001238 35.5107861853502 4.73163351338459 3.58408056507192e-06 -101.619243245239 73.2815703496601 -1.38669576484738 0.166669983608127 ACTR6 essential 0.00416310252340225 1 0.0381346172123652 4.73163351338459 -1.38669576484738 3.93475803984726e-11 79.512852065111 12.2724011671933 6.47899714015752 4.33416273396092e-10 -7.85837822093129 24.6738766560369 -0.318489807275931 0.750358738483457 TIPIN other 4.55841718916305e-07 1 5.67255218620805e-06 6.47899714015752 -0.318489807275931 0.0008003703141747 206.929696512987 76.3914423807236 2.70880729652518 0.00719752976348912 -473.40175196869 262.930803585589 -1.80048037549388 0.0729348935133764 SRI other 1 1 1 2.70880729652518 -1.80048037549388 5.34995895510903e-09 447.679722409448 100.195516342042 4.46806143381889 1.15892181988882e-05 -153.571527451554 146.810733131511 -1.04605109024275 0.29646613021537 EIF4G3 other 5.54148748570193e-05 1 0.11841863155624 4.46806143381889 -1.04605109024275 8.48941328431128e-11 189.558419518527 28.390130830807 6.67691250344051 1.37605837367912e-10 -28.0638022182416 62.466264190925 -0.44926333568574 0.653600783086789 NUP37 other 9.6898163227129e-07 1 1.83180890704164e-06 6.67691250344051 -0.44926333568574 0.527350192889491 10.5817682586303 42.9540050449343 0.246351143451249 0.805603319667148 -141.167867706373 145.377268625812 -0.971044985510947 0.332421477506388 SEMA3A other 1 1 1 0.246351143451249 -0.971044985510947 1.26463665037641e-08 141.69638755861 26.0562966757256 5.43808620703251 1.20959747911577e-07 -37.9259880895029 57.0563789986095 -0.664710743218163 0.506804947742053 GTSE1 other 0.000128019168117604 1 0.00142357527317135 5.43808620703251 -0.664710743218163 0.998836263482524 -6.41133140907882 165.676461499962 -0.0386979016272646 0.969160164959141 -20.0328265547103 497.803067892911 -0.0402424730717405 0.96792989103515 SEMA3C other 1 1 1 -0.0386979016272646 -0.0402424730717405 0.000186836161565498 72.7078759176138 20.6005797037127 3.52940921873719 0.000489725166759418 -32.2872143412499 45.1098058098605 -0.715747136605768 0.474768323550972 TTC38 other 1 1 1 3.52940921873719 -0.715747136605768 2.89198027710396e-08 233.403590421821 49.7643575414904 4.69017590003495 4.34676516444381e-06 -93.0339636381904 87.6154343218439 -1.06184446106199 0.289258671685175 ACAT1 other 0.0002867976840804 1 0.0459583480836644 4.69017590003495 -1.06184446106199 5.16262783221372e-07 161.153074190079 59.6509369880062 2.70160172374964 0.00734240472125562 -445.921127445026 131.593510159019 -3.38862552496828 0.000808436471453936 GRAMD4 other 0.00470831658297891 1 1 2.70160172374964 -3.38862552496828 5.51481832910101e-10 937.938027267528 275.929081421314 3.39919961475679 0.000779071263912482 -2492.99015915442 608.715943330202 -4.09549016494559 5.58920824546436e-05 CELSR1 other 6.04313792502889e-06 0.841958330096751 1 3.39919961475679 -4.09549016494559 3.32780519067418e-05 282.989034992551 61.992186211539 4.5649145849913 7.56449991778579e-06 278.697472427326 276.622693466025 1.00750039317203 0.314586508984602 ZNF638 other 0.259535526820679 1 0.078428735147603 4.5649145849913 1.00750039317203 2.88193227887842e-08 93.8139812158174 19.0541727820707 4.92353996622163 1.50266701009348e-06 -131.378367642065 65.7695168291028 -1.99755713552591 0.0467946997332173 SLC25A40 other 0.000285887682064739 1 0.0164572090945438 4.92353996622163 -1.99755713552591 2.63376665208841e-17 135.785813313846 24.2193346855105 5.60650468219022 5.12951508428696e-08 -122.606575728974 37.3521083937237 -3.28245394976352 0.00116570372193923 TIMM21 other 3.6849029229369e-13 1 0.000615746990717806 5.60650468219022 -3.28245394976352 0.0176248601382392 242.736428351223 87.5793587601294 2.77161687168836 0.00596138921253974 -223.575120011851 397.096270986954 -0.563024979953024 0.573879970685072 ADD2 other 1 1 1 2.77161687168836 -0.563024979953024 0.859301560725451 -9.23870875402695 17.157459581326 -0.538466007175227 0.590767207060306 -15.4908286482645 57.7746961178183 -0.268124796652752 0.788839467518195 FGF4 other 1 1 1 -0.538466007175227 -0.268124796652752 0.00324376883868575 119.952116885886 39.5078725959673 3.03615732774561 0.00263301446272894 -154.239834191623 123.978813894502 -1.24408218909782 0.214560376981683 RASAL2 other 1 1 1 3.03615732774561 -1.24408218909782 1.36002629288677e-06 5.7770627441971 37.7690913070425 0.152957419526794 0.878549140691807 -261.511642312515 61.5437157487046 -4.24920138686978 2.98096289182924e-05 VPS9D1 other 0.0119886317717969 0.453106359558044 1 0.152957419526794 -4.24920138686978 6.95145257772242e-05 6.82285743298116 29.3674952992295 0.232326841750109 0.816472732122413 -181.033179325752 49.9346124599547 -3.62540471243133 0.000349040559569638 ZNF37A other 0.524626126040711 1 1 0.232326841750109 -3.62540471243133 6.26705615554956e-30 616.598883434207 53.334496386848 11.5609769512375 2.38120474407195e-25 -80.9433292538181 125.706769134311 -0.643905891554135 0.520187120840231 MARK3 other 9.81609005643728e-26 1 3.7232517378309e-21 11.5609769512375 -0.643905891554135 3.30643333042123e-10 1465.25099088528 238.106151383201 6.15377209859293 2.72203268380606e-09 -592.73584773243 513.629097468736 -1.15401532088728 0.249514340323114 SLC25A3 essential 3.6665039201041e-06 1 3.45943133784912e-05 6.15377209859293 -1.15401532088728 2.53539435072576e-06 262.94152673705 50.7766265118809 5.17839692787637 4.45383633201697e-07 -205.474558823734 518.55409020126 -0.396245180023526 0.692245453124331 FNDC3B other 0.0218196037823459 1 0.00505644038773886 5.17839692787637 -0.396245180023526 0.290242051985866 -71.9981943839106 256.970980507872 -0.280180253200634 0.779551402110405 -1538.09678724861 988.679149913577 -1.55570873258839 0.120935853455001 FOSL2 other 1 1 1 -0.280180253200634 -1.55570873258839 0.673018373698426 -16.0598795276487 38.9520667443626 -0.412298521489184 0.680447795994938 -74.409532037835 85.6875002419441 -0.868382574211349 0.385956133805573 CACNG4 other 1 1 1 -0.412298521489184 -0.868382574211349 1.16736529026157e-14 101.476002438616 50.2202273782758 2.0206201312922 0.0443853165025913 -446.617315335356 82.462226924663 -5.41602297186786 1.43039221257621e-07 FRYL other 1.52866484759752e-10 0.00225816018599406 1 2.0206201312922 -5.41602297186786 0.000152282465434421 316.668217958217 76.3915924666038 4.14532814061514 4.56572554783937e-05 -108.633050173787 335.677296382815 -0.323623466181338 0.746477410659973 TMEM131 other 1 1 0.442647091863027 4.14532814061514 -0.323623466181338 1.95061812928528e-05 2941.35545810748 620.356471073796 4.74139562535099 3.42248453065765e-06 1156.69767314445 1633.93218720262 0.70792269238834 0.479597214935081 FSCN1 other 0.155854388529894 1 0.0364528827360347 4.74139562535099 0.70792269238834 0.0324493312599202 6976.41372081059 3485.45747460192 2.00157763267715 0.0463196383796311 -11470.8216896474 9180.20754264134 -1.24951659713207 0.21254637995602 ACTB essential 1 1 1 2.00157763267715 -1.24951659713207 0.135234001601928 108.169002229845 54.8976955667147 1.97037418626055 0.0498364357624389 46.3741015969982 99.0256052542287 0.468304146972309 0.63995205495168 MOCOS other 1 1 1 1.97037418626055 0.468304146972309 1.90124075320379e-13 239.758364422608 29.9109250546497 8.01574555064912 3.59504392839008e-14 382.65192723055 299.892486593628 1.27596370144833 0.203094067321362 PLD1 other 2.40278806389895e-09 1 5.19196244138096e-10 8.01574555064912 1.27596370144833 0.357970462759593 -69.1287306116555 75.209740135096 -0.919145984116984 0.358833593191556 -171.860825739673 120.153212927204 -1.43034731700265 0.153765087830359 ATP12A other 1 1 1 -0.919145984116984 -1.43034731700265 6.95165516950227e-17 194.789072663073 22.3273655312472 8.72423002124748 2.81237463038241e-16 -86.8580103119072 92.3341806651046 -0.940691840077518 0.347703641054933 WDR62 other 9.63499406493015e-13 1 4.18171983791561e-12 8.72423002124748 -0.940691840077518 2.13017750246867e-15 517.013953908308 59.8899714807644 8.63273000679861 6.0112764830405e-16 -295.479528365066 434.198542908032 -0.680517088763359 0.496780334386805 DLG1 other 2.84591714329814e-11 1 8.89909370549315e-12 8.63273000679861 -0.680517088763359 6.46950880733863e-22 1890.97661182733 186.872200091403 10.1190900032344 1.28984802048364e-20 -1480.30137485711 713.397679388612 -2.07500166825009 0.038933440116541 RAB7A other 9.67450347049419e-18 1 1.98030366584854e-16 10.1190900032344 -2.07500166825009 3.17081302618652e-05 156.748115371203 38.2335181764773 4.09975651855236 5.47109777354932e-05 -139.016240373894 134.790896459803 -1.03134739826699 0.303297485662717 BCAP29 other 0.247830746126738 1 0.526593160704122 4.09975651855236 -1.03134739826699 0.012888620791151 -26.6408149870399 17.082820130702 -1.55950919012253 0.120038634910051 -72.7222869920239 24.4932566905363 -2.96907381124709 0.00325330132164747 SEC31B other 1 1 1 -1.55950919012253 -2.96907381124709 1.88485748405153e-12 335.894684999392 56.9803119560602 5.89492534295729 1.111180596248e-08 -369.056419838337 122.586602737043 -3.01057710710843 0.00285339770065062 SART3 essential 2.29990310203967e-08 1 0.000137708611293015 5.89492534295729 -3.01057710710843 0.0362265221617727 -37.9860098477733 15.1883097597167 -2.50100310361867 0.0129837134977951 -12.1108387714856 35.6049039315477 -0.340145245013702 0.734014594296147 ARHGAP15 other 1 1 1 -2.50100310361867 -0.340145245013702 0.00449626300779828 178.335279348247 94.1823272510351 1.89351107106229 0.059347224784836 -481.765863679457 247.64617151188 -1.94537981644649 0.0527556800255796 EXOSC7 essential 1 1 1 1.89351107106229 -1.94537981644649 0.000130588069399687 158.066730983217 39.3776700138973 4.01412097077941 7.7283827236215e-05 -181.398575074518 136.715687171974 -1.32683073045113 0.185681578430177 KIFAP3 other 0.953945846964712 1 0.733655371953389 4.01412097077941 -1.32683073045113 1.35663646063426e-36 241.484051283271 17.9037690144579 13.4878891192276 4.05327643677099e-32 -109.175397231273 52.0775478955932 -2.09640049585575 0.0369670886614472 MKRN2 other 2.14755551718403e-32 1 6.40741939124757e-28 13.4878891192276 -2.09640049585575 4.65211341741255e-05 463.343633820663 107.598988155897 4.3062080950923 2.32930771295609e-05 60.1261610462261 260.222097844446 0.231057091401084 0.81744609251168 MCM6 essential 0.357189268188935 1 0.232022341287557 4.3062080950923 0.231057091401084 1.18948304730307e-13 177.649558916682 51.8081546867324 3.42898835117507 0.000699771206147522 -404.781238895668 90.9491398312322 -4.45063295427303 1.25011901955827e-05 REXO2 other 1.5130224361695e-09 0.191968276643368 1 3.42898835117507 -4.45063295427303 4.46653179068549e-13 145.534039118143 32.5484947596917 4.47129860205927 1.14270132688503e-05 -182.805092928761 57.1388349786838 -3.19931431918342 0.00154067299261178 RBM7 other 5.57065844934295e-09 1 0.116829783660726 4.47129860205927 -3.19931431918342 0.913698178634471 12.3693150027975 74.8982728474375 0.165148200786859 0.868950006807828 85.0303732715214 200.46781852642 0.424159717487598 0.671784602888547 RBMS2 other 1 1 1 0.165148200786859 0.424159717487598 1.80437754621978e-11 659.436190438127 106.627172908396 6.18450412264661 2.2756863275428e-09 -490.658990088722 285.391317262089 -1.71924988747337 0.0867065351919907 BAZ2A other 2.12014361680824e-07 1 2.90104493035156e-05 6.18450412264661 -1.71924988747337 5.23027887748714e-06 286.043980115697 62.5328593650506 4.57429874501414 7.27774811702015e-06 -110.425274494246 161.613215359936 -0.683268841897072 0.495020712049629 PTPN23 essential 0.0438558883877297 1 0.0756158029358394 4.57429874501414 -0.683268841897072 7.63217883036594e-31 255.534109592404 20.7294838629265 12.327085000385 4.89627357499361e-28 -56.4089151186486 64.7024041887194 -0.871821006127052 0.384074916942146 MLH1 ts 1.19741253669611e-26 1 7.69743168724746e-24 12.327085000385 -0.871821006127052 7.17509106414401e-10 455.916720825381 77.7494891190371 5.86391918443807 1.31194232485511e-08 -240.569925667168 167.269104159928 -1.43822092475102 0.151525178035197 UNG other 7.8172617143849e-06 1 0.0001620773548126 5.86391918443807 -1.43822092475102 0.0311214024480762 -37.5025747868014 19.2458168756393 -1.94860914603583 0.0523778841157278 -122.212344012811 63.1541480511236 -1.93514357780395 0.0540169189138813 FMO4 other 1 1 1 -1.94860914603583 -1.93514357780395 4.96284443132068e-14 105.032967258124 13.1107129360589 8.01123232354874 3.42329244516568e-14 -59.205182252182 42.0372793367565 -1.40839709862989 0.160163964210203 KLHL20 other 6.38718078310971e-10 1 4.94734224175345e-10 8.01123232354874 -1.40839709862989 0.594588294908809 -29.5033361090323 30.7185860801927 -0.960439260843973 0.337719695246932 -45.9438260374614 56.0556492038201 -0.819610988187973 0.413182868457433 RGS11 other 1 1 1 -0.960439260843973 -0.819610988187973 2.19759949951881e-12 251.158872114591 36.5906794386541 6.86401225578961 5.0342613339073e-11 -22.5052057623103 85.0145327324924 -0.264721866238157 0.791436743155557 SLC46A1 other 2.67403907101449e-08 1 6.79121853944095e-07 6.86401225578961 -0.264721866238157 0.672743511390151 21.463280328953 103.599845021886 0.207174830468317 0.836028909611996 -241.026447077092 286.849418693336 -0.8402542636308 0.401506542434216 PLXNA2 other 1 1 1 0.207174830468317 -0.8402542636308 6.70614880412108e-21 547.265872656512 61.3485441873646 8.920600804888 9.07688145629777e-17 -182.369211994382 139.107699481541 -1.31099294053513 0.191034902998817 SPAG5 other 9.91437039201261e-17 1 1.35608608957089e-12 8.920600804888 -1.31099294053513 0.000613741200510134 77.0757137159552 52.9865545894364 1.45462776950063 0.146929587185588 -341.714712390802 113.228956705238 -3.01790921981526 0.00278747419472488 ANKRD13A other 1 1 1 1.45462776950063 -3.01790921981526 2.96290261834495e-09 927.763279139372 162.965067771323 5.69301931896984 3.282951541797e-08 -423.244203005183 509.486700373729 -0.830726695504938 0.406870262436216 TPD52 other 3.11697355449889e-05 1 0.000397335625103691 5.69301931896984 -0.830726695504938 0.114307071641962 48.2444961208825 26.6144302124356 1.81271948096564 0.0709815337934748 -25.9563040740892 57.2578926215864 -0.453322727848764 0.650679132392692 ACACB other 1 1 1 1.81271948096564 -0.453322727848764 8.78997360309863e-12 698.413714569017 109.047365356059 6.40468215154551 6.97780748336397e-10 -192.405506020396 246.38230808397 -0.780922573202056 0.435555754246404 TRAF4 other 1.0450399616724e-07 1 9.06486970163813e-06 6.40468215154551 -0.780922573202056 0.0426965275974019 44.1059289072722 29.646581447193 1.4877239382839 0.137999343601189 -132.093989852999 96.2389311487688 -1.37256293556299 0.171035803266722 PAG1 other 1 1 1 1.4877239382839 -1.37256293556299 6.67288470021382e-27 102.15939358515 8.91787181157252 11.4555799571575 5.59016881364971e-25 -55.1629561675506 32.041944336211 -1.72158579356903 0.0863028165834443 GPATCH1 other 1.03242872081708e-22 1 8.73687483885313e-21 11.4555799571575 -1.72158579356903 0.0623913971460518 17.2977231423722 30.3625140363889 0.569706550703976 0.569346956985964 -114.389167835301 64.6537070525964 -1.76925922812507 0.0779711536343079 ICAM3 other 1 1 1 0.569706550703976 -1.76925922812507 1.00312897090253e-13 221.349419735448 84.939904947788 2.60595323095205 0.00966669150661106 -633.797102791903 128.81744745817 -4.92011847228779 1.49999780072861e-06 NT5C2 other 1.27838756051818e-09 0.0234119656737722 1 2.60595323095205 -4.92011847228779 6.45325113571892e-11 195.815053350591 45.9583432422689 4.26070740449355 2.81119027661674e-05 -310.838561051282 102.471712552466 -3.03340847252973 0.00265181510006942 CAMSAP3 other 7.40575100335104e-07 1 0.278251613579524 4.26070740449355 -3.03340847252973 0.000948477089965932 368.825721737795 97.5898552331164 3.77934490072526 0.000193251131543207 330.63449812519 143.339093874128 2.30665960826803 0.0218254579680855 RAP1GAP other 1 1 1 3.77934490072526 2.30665960826803 1.04141375413086e-28 453.591395785212 43.5655720201518 10.4116937928738 1.38390288548698e-21 -161.202021846273 97.1366341406078 -1.659538888417 0.0981597279259548 XAB2 essential 1.6227309116867e-24 1 2.13411663970948e-17 10.4116937928738 -1.659538888417 6.12817648328624e-26 576.53195152311 62.3667098823567 9.24422584758168 7.13240298364103e-18 -331.548631268286 139.05687448781 -2.38426638373315 0.0177990336073704 STXBP2 other 9.43677896661248e-22 1 1.07606563814192e-13 9.24422584758168 -2.38426638373315 8.28505948227268e-30 308.321342626672 30.4100910208168 10.1387839456191 1.03813088339345e-20 -179.625831204791 70.088776252211 -2.5628330356121 0.010918744573753 MAP2K7 other 1.29694321135497e-25 1 1.59498428924569e-16 10.1387839456191 -2.5628330356121 0.129970195432219 135.358606695975 75.465793584772 1.7936418642961 0.073981052161178 19.240284071694 115.299427121944 0.166872330175109 0.867594491114562 DGKD other 1 1 1 1.7936418642961 0.166872330175109 0.00522026802482485 31.6396225180531 17.8315143749094 1.77436542140095 0.0771422258456266 -103.065119502243 51.1802781729026 -2.01376630181761 0.0450371857108574 CTTNBP2 other 1 1 1 1.77436542140095 -2.01376630181761 0.044777107643767 90.1882841783784 39.2307349377419 2.29891905725204 0.0222733952650505 179.09625221726 105.667454440488 1.69490457743664 0.091246456464495 RARB og 1 1 1 2.29891905725204 1.69490457743664 2.31600052651876e-21 1502.59724538352 174.602456220276 8.6058196311274 6.16819634277191e-16 -315.022413672024 274.398075786084 -1.14804891677743 0.251957058859514 TM9SF3 other 3.44273478267013e-17 1 9.12708012839959e-12 8.6058196311274 -1.14804891677743 0.0130465730960756 201.274453377653 202.508737948403 0.99390503055199 0.321152455003783 -468.773530722806 285.62451742383 -1.6412230117739 0.101906874907842 NFKB2 other 1 1 1 0.99390503055199 -1.6412230117739 9.14634005870704e-11 266.961069298547 38.7418551523403 6.89076628490828 3.83112763484936e-11 -105.983253885405 105.893832920456 -1.00084443977975 0.317788295488687 UBE2T other 1.04249983989143e-06 1 5.18313257718769e-07 6.89076628490828 -1.00084443977975 0.28802959883947 -121.339545765419 82.6013954716472 -1.46897694733339 0.142990392125574 -169.192443209488 233.063305362904 -0.725950586455632 0.46849095781061 PPP1R12B other 1 1 1 -1.46897694733339 -0.725950586455632 9.97332832375203e-07 573.306985994161 126.004939212814 4.54987708875352 8.10791577037747e-06 -394.422248550755 330.636968215451 -1.1929163598359 0.233945506026801 DNAJC10 other 0.00888025153946881 1 0.0839007123918661 4.54987708875352 -1.1929163598359 3.91595683580783e-71 4824.65049807054 193.173694396625 24.97571169377 1.35063252266315e-71 3227.59400850442 609.33076644917 5.29694902378389 2.47712799054279e-07 GTF3C1 essential 6.24869232289856e-67 0.00390345828749733 2.15547444291812e-67 24.97571169377 5.29694902378389 0.236840338816685 -90.2466560038774 98.0811902557572 -0.920121949667919 0.358339588167774 -510.461380184982 307.561611341149 -1.65970446688412 0.0981479394545752 IL4R other 1 1 1 -0.920121949667919 -1.65970446688412 3.93373999987675e-17 306.616315481754 48.5600735972016 6.314164966575 1.11182194273136e-09 -222.425328750699 83.7932188219669 -2.65445500098617 0.00841517177428206 USP33 other 5.48402693382818e-13 1 1.43480621709482e-05 6.314164966575 -2.65445500098617 1.22310975867372e-07 175.154692345012 33.7887640111662 5.18381472276193 4.25562943078587e-07 -119.223469107937 119.440960472059 -0.99817908895523 0.319082956369685 SNRPA other 0.00116488973416085 1 0.00483779953691737 5.18381472276193 -0.99817908895523 0.053113506784644 36.842984976795 25.1669502050508 1.46394317454488 0.144372740835936 -34.0598440910876 42.1063431383 -0.808900549240685 0.419284558163797 SPAG6 other 1 1 1 1.46394317454488 -0.808900549240685 1.07316535781318e-17 195.995842068483 23.744765361107 8.25427579880478 6.59522506107988e-15 -137.153703703703 72.025743851048 -1.90423168676109 0.0579311922993101 EXOSC5 essential 1.51187535608721e-13 1 9.63628333674381e-11 8.25427579880478 -1.90423168676109 7.02325590564103e-20 294.097491513264 32.6332833210349 9.01219434832945 3.79864674169465e-17 -143.8439597728 96.6681626099868 -1.48801793567906 0.137913132120821 DYNC1I2 essential 1.02483350175114e-15 1 5.69417146580028e-13 9.01219434832945 -1.48801793567906 0.184041161581732 -24.9613275998976 28.2295090062085 -0.884228188113647 0.377356842256526 -85.7297692513301 46.5449165489328 -1.84187180056929 0.0665864950100983 APBB1IP other 1 1 1 -0.884228188113647 -1.84187180056929 4.65833128403492e-09 157.019901161635 30.2662672811689 5.18795065486418 4.16088142569242e-07 -325.046467664519 131.76501158638 -2.46686479021352 0.0142466997243746 LRCH4 other 4.83814287159867e-05 1 0.00473466697429541 5.18795065486418 -2.46686479021352 2.63252173955846e-08 95.3023704099545 21.585403326105 4.4151303994722 1.46336584326456e-05 -51.1548973204064 38.4774156248757 -1.32947851329533 0.184816494019319 FAM76B other 0.000261488384390342 1 0.148209692605834 4.4151303994722 -1.32947851329533 2.01281730276914e-12 39.1309231520333 18.0500701165286 2.16790975876603 0.0310296489922873 -150.626962001731 31.5852142450358 -4.76890740183611 3.01810959421912e-06 SIRT6 other 2.45322172861502e-08 0.0469074593133536 1 2.16790975876603 -4.76890740183611 1.35045744177912e-22 227.456068663928 22.4742873849944 10.1207243979534 1.24444129447028e-20 -4.5214513526283 58.3930999496604 -0.0774312608257852 0.938337610112288 POLD3 essential 2.03149312966833e-18 1 1.91096405178856e-16 10.1207243979534 -0.0774312608257852 0.152274033178748 1.7143934894621 7.2279132221796 0.237190657491751 0.812686777591376 39.2884083211608 20.1846809742567 1.94644683120178 0.0526268174742258 ACTN2 other 1 1 1 0.237190657491751 1.94644683120178 1.65194937229942e-24 453.689179441598 181.935165332059 2.49368602608268 0.0132368160966398 -2041.33300954012 267.181466174724 -7.64024929859912 3.71734976815888e-13 CAPZB other 2.52252669150121e-20 5.93512063984246e-09 1 2.49368602608268 -7.64024929859912 0.130986964981929 59.4589058674083 34.2384012959982 1.7366145502348 0.0835832637443222 -80.4572231700566 95.4270029774613 -0.843128471603154 0.399894696149198 GPR137B other 1 1 1 1.7366145502348 -0.843128471603154 0.00813569399799037 11.5495888571909 3.87625904496802 2.97957095312915 0.00315333573625523 4.30486898568792 7.82742739976928 0.549972393971333 0.582799796841863 NAALAD2 other 1 1 1 2.97957095312915 0.549972393971333 2.52032184995566e-09 93.922936297046 44.4340869666316 2.11375866387395 0.0354496195631667 -212.056827053685 62.1554890855546 -3.41171520284873 0.000744060060190317 JADE1 other 2.66284600002105e-05 1 1 2.11375866387395 -3.41171520284873 0.199967275272069 379.187428314897 244.233265682806 1.55256257682506 0.122165925298645 -14.1567833611173 526.735174998145 -0.0268764723395722 0.978586028615176 FGFR1 og 1 1 1 1.55256257682506 -0.0268764723395722 0.561006674255989 -5.63592779573602 8.75958457514204 -0.643401264910401 0.520503847755982 -20.4858351796026 19.5674297347925 -1.04693541549697 0.296055396057534 SMC1B other 1 1 1 -0.643401264910401 -1.04693541549697 0.00108504163745943 1657.74126956743 472.953485435743 3.50508310143885 0.000533353901018072 193.648079123233 1056.49805817864 0.183292413671896 0.854704641068804 FBLN1 other 1 1 1 3.50508310143885 0.183292413671896 0.263183413794668 56.9874615502927 70.6043501216897 0.807138107667194 0.420294741550691 -85.5744309443242 119.077306412726 -0.718646008398277 0.472978210656462 ITGA8 other 1 1 1 0.807138107667194 -0.718646008398277 0.0474374888091536 -37.9988368195691 16.0009916098143 -2.37478012276829 0.0182744280806323 -75.3475103178965 53.2759479597446 -1.41428755758282 0.158455735638506 CST7 other 1 1 1 -2.37478012276829 -1.41428755758282 0.525943313844178 148.129730434117 135.164085410491 1.09592522291887 0.274099020951712 62.0297605846139 234.426329724358 0.264602362104758 0.791519942797691 MAP2 other 1 1 1 1.09592522291887 0.264602362104758 2.02592947153541e-25 390.311649480414 37.9179307397073 10.2935904429954 3.43793487959805e-21 -70.5781859728775 65.3004081859371 -1.08082304435085 0.280736726625529 PIAS2 other 3.11142248238408e-21 1 5.29132557318936e-17 10.2935904429954 -1.08082304435085 0.588003332270897 10.834772417203 15.4622992664425 0.700721945067867 0.484075538305025 -19.2413613763929 39.9170967666299 -0.482033086947304 0.630170078779488 AMPH other 1 1 1 0.700721945067867 -0.482033086947304 1.03772600156142e-22 239.893334958785 21.7774003028994 11.0157012142007 2.35693224501023e-23 395.495210539147 233.791196709485 1.69165997738828 0.0919276746263887 MCCC1 other 1.56271158575134e-18 1 3.6650296409909e-19 11.0157012142007 1.69165997738828 0.331934222145181 97.8898566663382 117.333109902915 0.834290139819317 0.404895328847646 1553.30088483333 1259.6291474789 1.23314142733375 0.218654114751623 LAMP3 other 1 1 1 0.834290139819317 1.23314142733375 0.368066984879265 -80.6422196604513 57.0079770306283 -1.41457781631376 0.158348761959098 -66.3092608453236 141.727887539665 -0.467863184842617 0.640261255869208 FAP other 1 1 1 -1.41457781631376 -0.467863184842617 0.00027035346614152 251.363875001525 149.565778620007 1.68062425322674 0.0939881203474547 -545.761405965367 252.129559268756 -2.16460698836036 0.0312909721662502 NEBL other 1 1 1 1.68062425322674 -2.16460698836036 2.55778686933609e-09 151.2416396696 31.3838047203 4.81909829026472 2.40451499602234e-06 -189.34118394625 81.4847670713216 -2.32363901562759 0.0208848362723383 ACER3 other 2.70076715533198e-05 1 0.0259278852021089 4.81909829026472 -2.32363901562759 5.30284102805205e-21 425.871686834591 95.0514140425963 4.48043504795985 1.10110459724349e-05 -610.78562298608 141.000754357515 -4.33178975367323 2.08755174051018e-05 UBE2K other 7.85032585792826e-17 0.318581271119259 0.112676033435926 4.48043504795985 -4.33178975367323 8.62065188082015e-24 269.721179591184 35.7475093387852 7.5451740437352 7.12276814991244e-13 -221.285613523287 57.0453005432209 -3.87912082881618 0.000132100491888191 PIK3C3 essential 1.309735640253e-19 1 1.00658959494563e-08 7.5451740437352 -3.87912082881618 7.47808198360407e-12 135.837421174773 29.4949685005333 4.60544384620439 6.36623031857626e-06 -62.5516371866463 42.8850105851574 -1.4585897574267 0.145849010194569 N4BP2 other 8.91163029986097e-08 1 0.0664316133743433 4.60544384620439 -1.4585897574267 2.24457755644745e-12 76.8809160625284 10.3326962574799 7.44054737957425 1.31907693350634e-12 -27.3646084598137 47.7361906092936 -0.573246589443736 0.566951360897747 TIGAR other 2.73030413966268e-08 1 1.85356690696311e-08 7.44054737957425 -0.573246589443736 2.48100260715333e-22 286.925937398819 27.1137715434143 10.5822953084707 3.82560964420339e-22 -111.451271923762 128.228689847088 -0.86916018604469 0.385525814945973 TULP3 other 3.7247292141193e-18 1 5.91439250993843e-18 10.5822953084707 -0.86916018604469 1.638622223395e-05 137.261971402766 35.3303513387579 3.8851006627887 0.000128529815972055 -99.6139673966505 68.7542313962104 -1.44884126218508 0.148533761445492 SYNJ2 other 0.131745226760958 1 1 3.8851006627887 -1.44884126218508 0.0331144208963616 48.9922989622021 19.5910545595148 2.50074843155434 0.0129861118197741 -64.516228356468 114.553903070052 -0.563195374643981 0.573769244585483 ADCY2 other 1 1 1 2.50074843155434 -0.563195374643981 1.61513732197684e-18 634.454181786539 92.0825073746622 6.89006196589645 3.92223153634383e-11 -656.287415312496 204.295646390919 -3.21243955466722 0.00147566448783875 PPP2R5C other 2.30996939789128e-14 1 5.30521037605866e-07 6.89006196589645 -3.21243955466722 1.77066700933021e-23 2524.97628776299 373.445473767402 6.76129840935132 8.47962166928869e-11 -2450.65555192718 596.425091921686 -4.10890753108852 5.28167532821477e-05 GNB1 other 2.68415411944367e-19 0.796529456248069 1.13576052638453e-06 6.76129840935132 -4.10890753108852 0.081834716503112 67.9618461042776 79.1326326280522 0.858834640618104 0.391190757905992 -247.197495077842 152.473513398691 -1.62124876358994 0.106127177394355 EDN1 other 1 1 1 0.858834640618104 -1.62124876358994 3.65504830285269e-21 224.254511761155 37.16522272285 6.033988103165 5.27764278351327e-09 -236.069389883676 62.70855110443 -3.76454862576148 0.000204901463161608 MLLT10 og 5.42153314762139e-17 1 6.63135815748442e-05 6.033988103165 -3.76454862576148 2.08401978051246e-06 19.0322519722666 4.69901882545029 4.05026084790005 6.67842389367123e-05 -48.2115735588173 20.7190323840265 -2.32692206205471 0.020703878331676 ZCWPW1 other 0.0180767875761651 1 0.637856266084539 4.05026084790005 -2.32692206205471 0.000635281455173632 27.8806583607037 7.3970806538557 3.7691434858387 0.000200764784342558 5.87324538064922 20.2748601341003 0.289681178651931 0.772280042773729 ADCYAP1R1 other 1 1 1 3.7691434858387 0.289681178651931 1.09157510790045e-12 665.202828786826 107.767570345362 6.17256960192248 4.59048384209275e-09 -520.110590631227 277.992940091001 -1.87094891856235 0.0630311098603638 VDAC3 other 1.3431831702715e-08 1 5.78171439911582e-05 6.17256960192248 -1.87094891856235 2.65518595517097e-15 655.141476768196 126.619402625909 5.17410020250829 4.46206237583743e-07 -524.013302245004 214.636741382653 -2.44139609495281 0.0152706996635166 PCM1 other 3.5377697666698e-11 1 0.00506488700281307 5.17410020250829 -2.44139609495281 0.00647170977912499 65.6604942865808 25.6241401208957 2.56244673877024 0.0109326000515794 -65.2423092324806 56.9157478873819 -1.14629626516679 0.252680012865731 TNRC6C other 1 1 1 2.56244673877024 -1.14629626516679 4.30513217616024e-09 260.819611127745 42.9264413527348 6.07596630208735 4.21319241427462e-09 -161.601298553951 215.503416726931 -0.749878127262916 0.45398588059009 CBFA2T2 other 4.48035105572996e-05 1 5.31620618833172e-05 6.07596630208735 -0.749878127262916 0.0373673509186743 35.7362807331248 16.9845814320294 2.10404247382474 0.0362892826716294 71.9461391744897 31.9146177359824 2.25433184785959 0.0249682108835555 BRINP1 other 1 1 1 2.10404247382474 2.25433184785959 2.51760418387271e-17 258.204128392266 29.6641712505979 8.7042421044229 3.47438919192597e-16 -209.525843668004 131.451255497772 -1.59394326721783 0.112140716988528 ITCH other 3.52338705532986e-13 1 5.16016282784845e-12 8.7042421044229 -1.59394326721783 0.000539032882352251 4.15626018835055 4.62954477848465 0.89776865485055 0.370099961572506 -22.5684237981239 7.63576065888219 -2.95562221058769 0.00339286995752174 PKD2L2 other 1 1 1 0.89776865485055 -2.95562221058769 0.0111744418198431 -84.151272447425 55.4221937280579 -1.51836776545391 0.130109326835613 -706.812736421383 245.169471862828 -2.88295574098575 0.00426148053455618 TP53INP2 other 1 1 1 -1.51836776545391 -2.88295574098575 5.89995962927116e-14 881.268556793672 184.35443279782 4.78029491029463 2.92122444335492e-06 -850.408872085855 289.433022779196 -2.93818882144149 0.00359541461348799 SDF4 other 7.57613815994709e-10 1 0.0313213684816515 4.78029491029463 -2.93818882144149 0.688424076562272 -30.5932299631001 48.0581485086801 -0.636587777774554 0.524938759727563 -157.495118103713 224.142794163895 -0.702655281385273 0.48288275662697 MYH7B other 1 1 1 -0.636587777774554 -0.702655281385273 0.537087655983884 -13.1229608623131 11.765526645638 -1.11537385937401 0.265689385979912 -11.2413605332997 60.37138936083 -0.186203442596159 0.852426087748369 BPIFB2 other 1 1 1 -1.11537385937401 -0.186203442596159 4.41424449483681e-06 274.031205512215 93.5299737185649 2.92987578866199 0.00368299031437733 -268.032453379256 147.049156639913 -1.82274050054976 0.0694568611011718 TP73 other 0.0372738805144021 1 1 2.92987578866199 -1.82274050054976 1.04203170616995e-06 -85.2618645369402 95.2682727051053 -0.894965995666374 0.371593644661684 -644.933506347579 143.410630426 -4.49711087965941 1.01953215887202e-05 TOLLIP other 0.00926261983614464 0.156814241356105 1 -0.894965995666374 -4.49711087965941 8.42535348971428e-14 94.4430384984341 14.427353144793 6.5461098477734 2.9450514121221e-10 -111.363919192161 41.7314375482111 -2.66858574098975 0.00807637268283426 UBE2D4 other 1.07684442952038e-09 1 3.87480414292905e-06 6.5461098477734 -2.66858574098975 0.00215310506764257 30.2740845953947 10.640411128251 2.84519876445517 0.0048076407683744 -19.2323557860813 23.3969830433383 -0.822001526883067 0.411862434005504 CLUL1 other 1 1 1 2.84519876445517 -0.822001526883067 0.36344149460221 7.37711392684197 8.58377280506913 0.859425580612459 0.390873842285367 -25.3657530344657 30.2236789141713 -0.83926755265297 0.402067188706154 RUNX1T1 other 1 1 1 0.859425580612459 -0.83926755265297 0.713707253427798 -1.36339726761967 4.52990498354339 -0.300977012227128 0.763664529434836 -13.1261499158534 16.03734575533 -0.818473961720936 0.413811056096302 CDH17 other 1 1 1 -0.300977012227128 -0.818473961720936 3.42111662329697e-12 265.09008174713 39.4787759788756 6.71474925891763 1.276264151385e-10 -65.7891136904072 86.7790321236127 -0.75812223391353 0.449097624209446 THOC1 essential 4.13134043429343e-08 1 1.70100486096593e-06 6.71474925891763 -0.75812223391353 0.986296706762021 -0.194308174557286 10.8070001094784 -0.0179798438594321 0.985668411825698 -4.9545799840815 30.5526880491903 -0.162165108880258 0.871298949828398 FKBP7 other 1 1 1 -0.0179798438594321 -0.162165108880258 0.0110969052709273 61.6161208781245 22.7402145649074 2.70956638083839 0.0071714477880964 -26.4176837174198 64.3190396979325 -0.410728826821539 0.681599585543884 OSBPL6 other 1 1 1 2.70956638083839 -0.410728826821539 3.81015908920475e-07 289.749226541194 53.1964397248007 5.446778544582 1.1641794060828e-07 -111.914501866607 355.992147685942 -0.314373512433027 0.753482878329366 SLC1A3 other 0.00351220464842893 1 0.00137175259418737 5.446778544582 -0.314373512433027 1.06332337522267e-17 1757.91723143917 345.059989951046 5.09452640883856 6.53213018251004e-07 -2073.66760946129 519.033453738247 -3.99524846525029 8.31825759085539e-05 XRCC5 essential 1.49822263568874e-13 1 0.00733492898194052 5.09452640883856 -3.99524846525029 0.194589727676675 33.3626031961836 18.3877365103364 1.81439423919465 0.0707784618882335 19.9086313464916 124.59126911186 0.159791544691766 0.873170311962724 LXN other 1 1 1 1.81439423919465 0.159791544691766 0.0735259877471112 -27.1053187112008 18.2669456031129 -1.4838451539803 0.139012111396865 -64.7981868436588 28.4602481075727 -2.27679627383211 0.0235781975210342 SP140 other 1 1 1 -1.4838451539803 -2.27679627383211 0.000387039097788724 92.5960733246516 45.6897932729309 2.02662491317312 0.043676338213706 -150.766298025794 80.384608300738 -1.87556176751824 0.0617865922704001 MKNK1 other 1 1 1 2.02662491317312 -1.87556176751824 0.395852596756895 704.895522388063 778.20132899296 0.905800974794325 0.365839936289612 -417.303482587063 1170.70466724357 -0.356454957653499 0.721775210730587 TNS1 other 1 1 1 0.905800974794325 -0.356454957653499 2.70727691649821e-12 393.286893283216 95.6969525482562 4.10971178089393 5.24855110741534e-05 -371.947720215722 149.762839463109 -2.48357817966816 0.01360967667238 SAR1A other 3.28149035048748e-08 1 0.505802870221616 4.10971178089393 -2.48357817966816 0.0518699228754937 7.89812998767712 21.1683592033684 0.37311016464707 0.7093581278076 -52.1674995490832 30.421991658072 -1.71479566937694 0.0875258740956214 CDC14A other 1 1 1 0.37311016464707 -1.71479566937694 0.322668169860326 -40.8678444295083 28.7508000072543 -1.42145068725728 0.156339771849347 0.738033280575053 73.2199798748317 0.010079670628655 0.991965166203496 RAPGEF3 other 1 1 1 -1.42145068725728 0.010079670628655 0.0124089645251352 26.3032182430133 46.1566056039678 0.569868990555756 0.569242167755208 -365.723433786462 142.549660946689 -2.56558613579049 0.010842567072867 CEACAM1 other 1 1 1 0.569868990555756 -2.56558613579049 1.96805181962837e-12 174.957922540515 26.9548767702552 6.49077063240673 4.07219014388447e-10 -127.107433271624 68.6124135970135 -1.85254280687711 0.0650391585850597 SENP1 other 2.39885836294502e-08 1 5.33497630750305e-06 6.49077063240673 -1.85254280687711 0.629887487691622 1.99381401321765 3.90605154620955 0.510442319982299 0.610163352959622 -2.059620384001 6.02905748547558 -0.341615648708405 0.732908865600979 DUSP13 other 1 1 1 0.510442319982299 -0.341615648708405 5.20770519603344e-10 391.302426171583 97.5243891068059 4.01235454797917 7.79757695066537e-05 -966.883367807542 266.533920652054 -3.62761844887187 0.00034218455557518 CIC og 5.71649799368591e-06 1 0.74006802838765 4.01235454797917 -3.62761844887187 1.58223587556982e-05 26.3997534507378 8.80209165187073 2.99925909600441 0.00296085634717735 -57.2978795811518 24.1285574974308 -2.37469146621188 0.0182679807723396 LIPE other 0.127417455059638 1 1 2.99925909600441 -2.37469146621188 5.71936271061538e-14 1468.1088772491 276.901980914693 5.30190817848066 2.3799048611264e-07 -848.020318550197 466.720259583365 -1.8169777316014 0.0703250152954266 FDFT1 other 7.34709333805652e-10 1 0.00275117001946212 5.30190817848066 -1.8169777316014 9.58724743489887e-13 297.180477923819 46.4314524567461 6.4004131294549 6.85848766833278e-10 -233.691584788454 126.897047786812 -1.84158409406859 0.066636871766395 PAFAH1B3 other 1.18287458851782e-08 1 8.91191887623161e-06 6.4004131294549 -1.84158409406859 7.66305644631739e-18 624.717471836151 82.7153069022636 7.55262230453086 6.92089264545523e-13 -229.315944405584 164.08839411696 -1.39751470931046 0.163427714888185 KIF22 other 1.08271324530018e-13 1 9.78268175435097e-09 7.55262230453086 -1.39751470931046 0.618299028532981 18.6912564891915 101.264764444554 0.18457808687666 0.853697517401418 -147.123819693387 177.586356478228 -0.828463529581028 0.408134393002313 SCGN other 1 1 1 0.18457808687666 -0.828463529581028 6.01669070869543e-05 196.332712414374 59.1509113066639 3.31918322266415 0.00102700697690387 -165.016921967589 104.119545051701 -1.58487939882612 0.114164243879105 CARMIL1 other 0.457388827675026 1 1 3.31918322266415 -1.58487939882612 1.84290547104738e-37 503.891885419303 35.562054968741 14.1693691734694 1.54480936259112e-34 -255.282838545979 141.262809051495 -1.80714825267931 0.0718399764442474 PGM1 other 2.91916226613904e-33 1 2.44805939689815e-30 14.1693691734694 -1.80714825267931 9.98180694217293e-13 596.280484973378 79.6586921068181 7.4854415657967 1.03825508310207e-12 -106.345394539743 249.015084806963 -0.427064065705827 0.669676839788623 DDX1 essential 1.23035752369224e-08 1 1.46217463353265e-08 7.4854415657967 -0.427064065705827 1.58977872288106e-15 487.982087612116 107.264704964504 4.54932578030769 8.1514387753823e-06 -910.007700506953 205.81488902262 -4.42148624343178 1.42380774829639e-05 DNM2 other 2.13093940014977e-11 0.218326680123768 0.0843103312537791 4.54932578030769 -4.42148624343178 0.0119541960676038 211.578831450095 98.6231342025945 2.14532658245745 0.03281219142424 -231.615440025394 184.026958936941 -1.25859516107507 0.209255787696455 EPB41L2 other 1 1 1 2.14532658245745 -1.25859516107507 0.929645585599391 -1.25047793475843 3.7128384183916 -0.336798371985211 0.736540594294671 0.608986838067281 8.55917717252498 0.0711501614924077 0.943332943484582 RIMS1 other 1 1 1 -0.336798371985211 0.0711501614924077 0.183107384674268 -176.315279715192 182.233057999169 -0.96752631850142 0.334143647402565 -620.345604925433 344.603268796829 -1.80017330390205 0.0729452785086595 MOXD1 other 1 1 1 -0.96752631850142 -1.80017330390205 7.45461113981347e-05 174.513899083305 51.8753916589006 3.36409795671129 0.000878843478411288 -164.343514422764 97.5032880981834 -1.68551766436096 0.0930397728566733 STX7 other 0.56044088570162 1 1 3.36409795671129 -1.68551766436096 4.22174397460689e-11 113.129241345178 24.3541268508545 4.64517746983846 5.41064785837327e-06 -152.138905609725 50.7530080620819 -2.99763327177822 0.00298526313501494 RABL2B other 4.88286908103033e-07 1 0.0567955705693442 4.64517746983846 -2.99763327177822 8.43561818376993e-20 889.846099305425 137.3800880002 6.47725672809389 4.35509077632196e-10 -1096.14323909437 280.874253465818 -3.90261202502056 0.000120033473266002 KEAP1 other 1.22999748737549e-15 1 5.69863628081729e-06 6.47725672809389 -3.90261202502056 0.364645209119198 3.56720207924243 8.84171528077757 0.403451362768686 0.686940327205254 -23.7812696467085 20.3715072860536 -1.16737899227463 0.244102723999319 DDX43 other 1 1 1 0.403451362768686 -1.16737899227463 0.30029964488263 -29.3310038633468 23.8281867661509 -1.23093729922467 0.219413567215825 -73.4061317987825 53.1978527976391 -1.37987020036343 0.168763974915298 PTPRH other 1 1 1 -1.23093729922467 -1.37987020036343 2.08903730628574e-26 349.963382160778 36.0214402829252 9.71541891196024 2.55005856363494e-19 -507.148783575404 119.429660656616 -4.24642237771703 2.99466109017365e-05 SLC35C2 other 3.22275785240701e-22 0.455098645873689 3.88883930954328e-15 9.71541891196024 -4.24642237771703 2.69463525980835e-05 126.242037244327 40.0921832060248 3.14879428230678 0.00183309696636435 -338.225552050473 144.41253616541 -2.34207888754942 0.0199406363530959 CRYBG3 other 0.212202526709908 1 1 3.14879428230678 -2.34207888754942 0.188546741527447 2.51072113824039 5.56851817637013 0.450877784487546 0.652470015449346 -31.5730629808452 20.139785115762 -1.56769611986253 0.118221980264069 EPHA6 other 1 1 1 0.450877784487546 -1.56769611986253 0.329399634982668 -28.5956115358898 19.2810050589004 -1.48309755889461 0.13920622646505 -35.659432508649 58.3676839350394 -0.61094479178472 0.54174632574789 SCTR other 1 1 1 -1.48309755889461 -0.61094479178472 2.33241597569247e-11 60.8927833489451 17.3015143051125 3.51950599670641 0.000508726248424622 -275.54646261502 59.344890068443 -4.64313713105256 5.40592497210907e-06 RFX3 other 2.72566130919422e-07 0.0836026296936668 1 3.51950599670641 -4.64313713105256 3.25398090632976e-10 377.903953194664 60.017450109119 6.29656795661242 1.23927528362545e-09 -47.6337587634153 140.030387292281 -0.340167300001754 0.73399700758163 RIF1 other 3.61029181557287e-06 1 1.59668227542302e-05 6.29656795661242 -0.340167300001754 5.84207290329704e-11 327.561598079759 58.0688674069289 5.64091591083233 4.32011134304177e-08 -432.985487338173 164.506964855868 -2.63201918361044 0.00898383296851227 RAB21 other 6.71604700963027e-07 1 0.000520452027175815 5.64091591083233 -2.63201918361044 0.022892690986368 -22.9279241045134 27.5684505391708 -0.831672569770874 0.406325999015105 -161.917509450619 59.8626240850406 -2.70481810521034 0.00726702887881118 SLC4A4 other 1 1 1 -0.831672569770874 -2.70481810521034 6.07351764412939e-14 1588.07490543637 213.575105910723 7.43567420306095 1.44409931279806e-12 -625.710467917404 730.218632490461 -0.856880994372021 0.392284870990881 SMARCA2 other 7.79535989624007e-10 1 2.02708220537464e-08 7.43567420306095 -0.856880994372021 0.000293571586944442 82.4108648064853 42.7380577519998 1.92827819375178 0.0548729126746098 -192.281017623861 74.5233574172233 -2.58014432371001 0.0104067025139803 SESN1 other 1 1 1 1.92827819375178 -2.58014432371001 0.0304805697922007 241.006662769695 123.001466472321 1.95938040156561 0.0510895144527451 -151.772387681084 244.499682199587 -0.620746768730729 0.535286040138489 COL5A3 other 1 1 1 1.95938040156561 -0.620746768730729 8.88780758896753e-13 730.625105499444 162.990135506922 4.48263389208862 1.09673682644112e-05 -1167.1097525977 335.701066304408 -3.47663403469615 0.000592848646530493 SRCAP essential 1.09746648108571e-08 1 0.112251014186248 4.48263389208862 -3.47663403469615 6.7026746454191e-40 378.86650443247 26.8408135301645 14.1153137555495 4.33375832913825e-34 -171.882554029781 91.9887545725391 -1.86851702502658 0.0627975286623978 PUM3 other 1.06331230574929e-35 1 6.8651065691879e-30 14.1153137555495 -1.86851702502658 0.411831356124154 33.7861482570575 37.0581846660313 0.911705431918446 0.362734080700561 76.2614154096683 58.6229419007942 1.30088004690592 0.194404542900015 CPB2 other 1 1 1 0.911705431918446 1.30088004690592 0.001688066916989 19.2412167636443 5.38336640865557 3.57419787230303 0.000415260731101715 18.3516608971055 10.4319175101299 1.75918385850781 0.0796664785958233 CHRNA3 other 1 1 1 3.57419787230303 1.75918385850781 0.947145736960308 -0.206588921282781 5.30759154901696 -0.0389232892875949 0.968979996711794 2.34762054272263 8.68151021891889 0.270416146905714 0.787044439024486 KCNN2 other 1 1 1 -0.0389232892875949 0.270416146905714 8.38260373448291e-17 101.464491902532 14.7547318742726 6.87674250993694 4.19300583846317e-11 -116.472665614976 40.2052878925977 -2.89694892687039 0.0040745130418857 CNOT4 other 1.15956557459102e-12 1 5.66684739068297e-07 6.87674250993694 -2.89694892687039 3.19412568484954e-17 314.316509967403 52.7582295826214 5.95767736055607 7.92436794109171e-09 -351.116997130032 96.5800121387617 -3.63550375853715 0.000331933800716472 PSEN1 other 4.46187416916633e-13 1 9.88089438574725e-05 5.95767736055607 -3.63550375853715 4.84964163333034e-16 360.020012257393 44.2787819576595 8.13075690748795 1.53792468191359e-14 -194.889865422721 155.1060665189 -1.25649415136817 0.210018870315141 CPOX other 6.58435844557260e-12 1 2.23460456282045e-10 8.13075690748795 -1.25649415136817 1.57404117025206e-11 902.877265959206 126.794302800062 7.12080311197364 9.86983464922099e-12 77.3236746945221 451.926231636736 0.171098000694671 0.864275816988037 CLDND1 other 1.8540630944399e-07 1 1.35848404111878e-07 7.12080311197364 0.171098000694671 1.58227946987286e-07 129.96340538268 23.0495194245723 5.63844317049538 4.31982094269434e-08 71.2151359783477 51.1032355994302 1.39355434431909 0.164598243779093 MOK other 0.00149493764313588 1 0.000520452027175815 5.63844317049538 1.39355434431909 1.44229184767632e-13 6525.9049070192 979.06147892346 6.66546999090889 1.48846861279365e-10 -2833.97286006036 2171.08398637758 -1.3053262231411 0.192897156358311 HSP90AA1 other 1.82911452122311e-09 1 1.97966325501555e-06 6.66546999090889 -1.3053262231411 5.66124997843537e-11 112.571754613203 16.9693916663473 6.63381203207469 1.79039904173805e-10 -59.6259542881045 65.9784648319956 -0.903718424487947 0.366953310558865 RBL1 other 6.51383422518773e-07 1 2.37514336876969e-06 6.63381203207469 -0.903718424487947 7.56609622649553e-19 613.535535824733 69.105532682066 8.87824045358896 9.98771424325877e-17 -588.792542888768 287.194000113718 -2.05015614064231 0.0413220750427323 DLGAP4 other 1.08800463737006e-14 1 1.4913654908034e-12 8.87824045358896 -2.05015614064231 0.678058799630248 7.50879125499258 12.3058966101382 0.610178314744368 0.542293544375707 -5.66196552449026 22.4230713372665 -0.252506244096911 0.800855625103338 IGSF9B other 1 1 1 0.610178314744368 -0.252506244096911 2.02493086852337e-05 23.6891778018539 6.33954407171094 3.73673209522473 0.000227190817099046 -3.21584807993259 9.62382908171352 -0.334154737436381 0.738520289893643 CROCCP3 other 0.161488236764739 1 1 3.73673209522473 -0.334154737436381 2.3061306937826e-11 225.794026059022 33.1652189713455 6.80815725215341 6.81225798399019e-11 12.4730208549595 71.6832601973576 0.174001863484151 0.861999399899356 NDC80 essential 2.69586678103186e-07 1 9.15363105308761e-07 6.80815725215341 0.174001863484151 2.70390060463235e-13 72.252035570036 12.3421100887431 5.8541072029438 1.38757835601983e-08 -58.7063650032003 23.7973504212193 -2.4669286270985 0.0142488207470874 AP4E1 other 3.39988462026471e-09 1 0.000171143914431486 5.8541072029438 -2.4669286270985 1.1385957302191e-17 106.611425201611 26.7652771634641 3.98319899885591 8.72709547473723e-05 -158.865343983701 39.3391475640453 -4.0383524763739 6.9997740769448e-05 RSBN1 other 1.60313979179809e-13 1 0.823052374222468 3.98319899885591 -4.0383524763739 0.00936997024744993 36.5871210719179 57.6933620744114 0.634165175271442 0.526504048611958 -160.816393381944 84.9447159806813 -1.89318889968999 0.0593902218815469 MAGI3 other 1 1 1 0.634165175271442 -1.89318889968999 0.309412616399191 -193.475432970716 247.496754869993 -0.781729170842444 0.435063819655054 -755.280252929758 492.025016572546 -1.53504441337364 0.125952605005094 CXCL2 other 1 1 1 -0.781729170842444 -1.53504441337364 0.31455896242971 38.6354191668097 69.2851257843364 0.557629342942524 0.577554462976495 -93.7331504657405 104.434330828688 -0.897531967907165 0.370225959191694 COL4A4 other 1 1 1 0.557629342942524 -0.897531967907165 0.146810350983038 66.779451404987 44.1126296379621 1.51383973145683 0.131223336704941 -24.4878449710102 70.6784647449646 -0.346468263839231 0.729257718428954 TCF7 other 1 1 1 1.51383973145683 -0.346468263839231 0.00310949971599091 68.9677880377886 44.5374519230374 1.54853466150169 0.122669279583709 -172.712514638274 77.6610033935764 -2.22392844659743 0.0269837141620248 OSTM1 other 1 1 1 1.54853466150169 -2.22392844659743 3.7402383629154e-17 605.009505569017 75.0437929235966 8.0620859100897 2.62313531009647e-14 -672.937632155689 276.545149679499 -2.43337347603308 0.0156229871493171 PCNP other 5.2168844685944e-13 1 3.79803761548868e-10 8.0620859100897 -2.43337347603308 1.87249637956093e-18 149.132482573782 24.8971167018698 5.9899499351498 6.65306591064168e-09 -177.39953937714 45.3464513657317 -3.91209309734875 0.000115754909769193 EXD2 other 2.67598457603052e-14 1 8.32165484103061e-05 5.9899499351498 -3.91209309734875 2.91003938197984e-18 311.22345119168 40.5008209439541 7.68437389509605 2.82860552521174e-13 -98.8576898233275 73.4345681502316 -1.34620101014396 0.179362667598906 ARG2 other 4.14418708387749e-14 1 4.0330257578469e-09 7.68437389509605 -1.34620101014396 0.0670282310085162 -98.8547267293393 54.4739212566669 -1.81471655516704 0.0706689410465194 -186.407969186897 85.9388258458479 -2.16907744959496 0.0309431418301774 MEF2C other 1 1 1 -1.81471655516704 -2.16907744959496 0.53535872685778 -127.055450035026 125.562232485299 -1.01189225072039 0.312498874042514 119.162006109758 334.449038545793 0.356293462908078 0.721900089881466 PTPRC other 1 1 1 -1.01189225072039 0.356293462908078 0.27896861712168 2547.72042626821 1634.55121265973 1.55866662759534 0.120233777830689 2435.28912770825 4500.26225153535 0.541143824868741 0.588849747878262 PKP1 other 1 1 1 1.55866662759534 0.541143824868741 1.1937926181591e-16 186.888379431782 21.876115776261 8.54303302026702 9.35001160719995e-16 -197.95553031169 107.440656770241 -1.84246388901935 0.0664916138835441 UBA5 other 1.64361367668145e-12 1 1.38062271391914e-11 8.54303302026702 -1.84246388901935 0.506712871943651 40.8399742911222 76.6264481680582 0.532974909675461 0.594486124944111 -163.171876244386 191.109483685977 -0.853813599917957 0.393959579164231 STK17B other 1 1 1 0.532974909675461 -0.853813599917957 1.07021087231425e-14 120.743089528776 22.9869920153999 5.25267026881485 3.03611277664415e-07 -171.938895667455 44.4701172829175 -3.86639177435906 0.000138346012499352 CDC14B other 1.40293943251676e-10 1 0.00348667191269815 5.25267026881485 -3.86639177435906 4.93232017593132e-13 57.2571509636198 9.64360595529353 5.93731755829265 8.8793060307693e-09 -42.6667927674213 18.63453319199 -2.28966254897984 0.0228126385987028 ZNF510 other 6.14419124315765e-09 1 0.000110511842858955 5.93731755829265 -2.28966254897984 0.585715113691963 -10.9166559594957 30.6526150656608 -0.356141097133512 0.722009967449129 -80.5872993273579 77.8601628795564 -1.03502608197751 0.301572687983071 LRP2 other 1 1 1 -0.356141097133512 -1.03502608197751 0.000126173532968196 56.4295371290201 15.0739979633946 3.74350170844208 0.000221763320020728 -9.61371649429678 34.8795990514167 -0.275625774256321 0.783046337934422 ZNF506 other 0.923211740728288 1 1 3.74350170844208 -0.275625774256321 0.000480941242982502 106.47400400195 26.9612915097896 3.9491433102635 9.98833203646272e-05 11.9823811600524 74.7203540853849 0.16036301362223 0.872713716966939 JMJD4 other 1 1 0.937305078301661 3.9491433102635 0.16036301362223 1.40708676076428e-20 109.788017275882 10.6119139514939 10.345731955396 2.21351171588967e-21 -21.5430881078774 37.1893405118644 -0.5792812620865 0.562877088615498 DUSP12 other 2.07151312919717e-16 1 3.41013614949962e-17 10.345731955396 -0.5792812620865 7.01166698990785e-06 230.618134860877 70.2407623347029 3.28325216292446 0.00116045774410263 -386.023312888591 143.615018916748 -2.68790350619501 0.00763362742975012 AACS other 0.058133731013326 1 1 3.28325216292446 -2.68790350619501 9.28583416735521e-11 158.240205408123 46.4472608538678 3.40687916787985 0.000756049710836922 -310.31332818616 77.0715994516989 -4.02629931639909 7.3469305779002e-05 KIAA0141 other 1.0582136617118e-06 1 1 3.40687916787985 -4.02629931639909 0.0938467141743483 -26.2926829906792 39.1478056614596 -0.671625971019978 0.502398206333949 -232.278074430586 106.618638014052 -2.17858789754912 0.0302305148310923 CADPS2 other 1 1 1 -0.671625971019978 -2.17858789754912 0.574731554567868 9.65962406387935 17.1348159983314 0.563742503264698 0.573392169018523 -15.7196012222611 29.8924777156884 -0.525871470801866 0.599404414844489 PCDHB4 other 1 1 1 0.563742503264698 -0.525871470801866 1.24280608760467e-05 167.131352073915 37.873515812231 4.41288189093712 1.48552419270975e-05 29.5434659603321 67.9489099830462 0.434789402327475 0.664069148398758 PCDHA6 other 0.100953138496127 1 0.150409324511862 4.41288189093712 0.434789402327475 0.00157416738880547 152.335377765665 176.677171043603 0.862224456424366 0.389323543888269 -834.992801579009 305.06788757657 -2.73707209307447 0.0066073945170485 PCDHGA2 other 1 1 1 0.862224456424366 -2.73707209307447 6.18488655507703e-10 96.2319980251916 27.084017398803 3.55309172225848 0.000448690031696007 -145.488841687816 47.9478474582495 -3.03431435195293 0.00264412793070518 HSPB11 other 6.76255495932122e-06 1 1 3.55309172225848 -3.03431435195293 3.13793642652384e-14 327.064938561444 48.6125886859872 6.7279885190669 1.00758208162937e-10 -86.3312232788055 86.258761618904 -1.00084004985165 0.317790414285775 PHLPP1 other 4.06362767234837e-10 1 1.34633117747317e-06 6.7279885190669 -1.00084004985165 2.20450545405257e-06 297.022970551752 134.899061278592 2.20181643768702 0.0285240902952981 -639.136496706462 226.254262265119 -2.82485947582963 0.00508300388160463 ATP8B1 other 0.0190752419018702 1 1 2.20181643768702 -2.82485947582963 0.0160413574817988 -46.8986327503977 29.3869733861587 -1.59589870430437 0.111672578005161 -131.253997039636 45.3131814356412 -2.8965963739725 0.00407895488709262 IL12RB2 other 1 1 1 -1.59589870430437 -2.8965963739725 0.137413594815144 53.5517537396159 32.5583182563911 1.64479483608168 0.101163052838352 -29.2428256921523 82.915925547771 -0.352680447078944 0.72460015389293 SMARCD3 other 1 1 1 1.64479483608168 -0.352680447078944 1.10423860114024e-37 216.72629538081 14.2772336612258 15.1798521004385 7.0704203567407e-38 -23.6080067450244 95.8280249773795 -0.246358064361622 0.805595785626596 WDR70 essential 1.7495556396466e-33 1 1.12249993583615e-33 15.1798521004385 -0.246358064361622 5.12628128135914e-10 64.2440799031474 11.2201965312399 5.72575353063341 2.76594196653453e-08 -32.2863559322033 24.0712757599529 -1.34128146153008 0.180968876588059 STRADB other 5.62865684693233e-06 1 0.000336144927192942 5.72575353063341 -1.34128146153008 8.57605461700136e-06 688.741378204753 166.961893690568 4.12514115035855 4.9639737860318e-05 -538.507966326568 384.037181757575 -1.40222872134944 0.162017268383856 BZW1 other 0.0706409618802402 1 0.47922202930351 4.12514115035855 -1.40222872134944 0.929363574037119 -0.599176311323829 7.78303311840577 -0.0769849366189721 0.938692544479739 3.95824216502885 14.0457332531847 0.281811002222428 0.778304309940638 PGR other 1 1 1 -0.0769849366189721 0.281811002222428 0.732973119642873 3.07740475413336 16.2370150780446 0.189530202401214 0.84982074949631 -75.442896404267 105.156792346854 -0.717432461760745 0.473732143588944 C1QTNF3 other 1 1 1 0.189530202401214 -0.717432461760745 6.84250035370956e-13 246.586111430212 52.4187417272642 4.70415930075553 4.08041742501512e-06 -253.338636798776 83.1843484973471 -3.04550845651998 0.00255341880088846 ME2 other 8.48880593881208e-09 1 0.0432565051225853 4.70415930075553 -3.04550845651998 1.1126262904163e-29 228.249812673918 17.7007914519837 12.8948930500132 9.10779238344818e-30 -86.9963911667918 115.363665093035 -0.754105645799597 0.451465591887491 C5orf22 other 1.74126014450151e-25 1 1.43566131340294e-25 12.8948930500132 -0.754105645799597 2.96835909606861e-07 88.9170193637252 34.4442273971939 2.58147811934865 0.0103655813350997 -313.695404936282 84.9226704969581 -3.69389472917622 0.000267289420014539 CCNT2 other 0.00275879294388616 1 1 2.58147811934865 -3.69389472917622 3.59671091180066e-07 153.407110208228 39.5177252728279 3.88198230412087 0.000131778355168262 -250.889041005145 91.330879147485 -2.74703411756279 0.00643914429613512 FAM135A other 0.00332300121141263 1 1 3.88198230412087 -2.74703411756279 0.114582262403333 37.6543930929406 21.9769575724096 1.71335786443037 0.0878526127465444 -32.9446419502287 50.7917609684703 -0.648621770973438 0.517162020347083 COL19A1 other 1 1 1 1.71335786443037 -0.648621770973438 0.0183402163478423 179.814726772089 75.5406103743276 2.38037164223389 0.017997296350426 -78.2918768254864 165.906015726014 -0.471904990803841 0.637380028503407 EPB41L3 other 1 1 1 2.38037164223389 -0.471904990803841 0.00235134498985241 328.30544762509 104.98173432834 3.12726256358355 0.00195663072381323 -77.8157640155421 257.007405224686 -0.302776349761255 0.762292583346816 COBLL1 other 1 1 1 3.12726256358355 -0.302776349761255 0.0656125522770707 53.0199360343445 23.2729641480384 2.27817718865061 0.0234917794996295 -13.3806963093924 63.315677758399 -0.211333066044885 0.832785634508951 KCNK2 other 1 1 1 2.27817718865061 -0.211333066044885 0.574386699833258 41.6900481940935 39.6956917628118 1.05024113052868 0.294549860881254 23.0383195672337 108.166227739034 0.212989951196383 0.831496122945176 SERTAD4 other 1 1 1 1.05024113052868 0.212989951196383 0.478197649094497 25.2536017431318 23.4627522778053 1.07632733978189 0.282734616040293 -27.8081568327548 64.3093590635069 -0.432412283961556 0.665784414645298 TRAF5 other 1 1 1 1.07632733978189 -0.432412283961556 8.49882123360937e-17 161.669692271854 25.6424152255761 6.3047763188314 1.15577750968874e-09 -124.149968271309 42.7816144569964 -2.90194677893942 0.00401088407124659 MRPL22 other 1.17547196482051e-12 1 1.4904906764946e-05 6.3047763188314 -2.90194677893942 3.93880785334591e-13 208.881556392728 26.733122973931 7.8135860369333 1.20580686846011e-13 104.518607471906 44.6013431356288 2.3433959635268 0.0198269157690851 GEMIN5 essential 4.92390369746772e-09 1 1.72804182319018e-09 7.8135860369333 2.3433959635268 0.190520847532042 17.4105330934532 12.2171886393839 1.4250850672247 0.155384845508374 -22.5344143429526 39.7691453499719 -0.566630591244742 0.571475572412763 OPRK1 other 1 1 1 1.4250850672247 -0.566630591244742 2.5772354501853e-05 1450.69447857897 410.898107202422 3.53054553708206 0.000487153117603776 -1487.39022939595 868.53813701161 -1.71252149561749 0.0879444487606509 NFE2L1 other 0.203369649374122 1 1 3.53054553708206 -1.71252149561749 0.12191704938478 24.4077269964473 16.6983486233454 1.46168507718923 0.144981845217739 -76.9423427586119 65.6610634426373 -1.17181079203553 0.242298419259296 SEMA5B other 1 1 1 1.46168507718923 -1.17181079203553 1.60343576315795e-16 457.675229675529 54.4221581717365 8.40972216190459 2.37478061684856e-15 -415.631509813373 209.667821116012 -1.98233332898232 0.0484518413058661 GSK3B other 2.20183798996849e-12 1 3.48997759452064e-11 8.40972216190459 -1.98233332898232 6.50406188284645e-05 726.354340474933 205.722708030068 3.53074460000191 0.00048708501021934 -1593.64450485659 789.336165976335 -2.01896805638622 0.0444788002027143 ITGB5 other 0.492747728244447 1 1 3.53074460000191 -2.01896805638622 4.20487369904158e-12 322.036777137763 43.4126542242253 7.41803934572742 1.62660586100485e-12 -38.6661184290207 195.347018595874 -0.197935544176447 0.843247818691279 ERC1 other 5.0559401357276e-08 1 2.28082673830101e-08 7.41803934572742 -0.197935544176447 1.72796527599481e-17 1220.46041132784 131.818390070373 9.25865056215812 8.16867600254458e-18 1859.68097016207 834.058738099914 2.22967626284769 0.0266265769751206 XPO1 essential 2.42502646833111e-13 1 1.23191802794375e-13 9.25865056215812 2.22967626284769 1.12378699911378e-10 326.842039408696 46.2666558405702 7.06431086212408 1.37217874330622e-11 159.153441935428 296.567971700626 0.536650808995948 0.591950743269641 RNF13 other 1.2750487291945e-06 1 1.88043374982684e-07 7.06431086212408 0.536650808995948 0.156825807158697 3.95503840888625 10.5581687662344 0.374595111752209 0.708257844121829 -29.7649814430799 19.9577961303467 -1.49139620670946 0.137033606700601 TRPM3 other 1 1 1 0.374595111752209 -1.49139620670946 6.26290933113448e-27 233.687667723517 21.8584679531686 10.6909444991382 1.67951483655669e-22 -25.6007922741311 45.7674008745198 -0.55936740529183 0.576371291624173 PALB2 other 9.69059960806439e-23 1 2.60022486995706e-18 10.6909444991382 -0.55936740529183 1.89283279897003e-13 139.716527709661 22.3921828230526 6.23952246253653 1.66717154830809e-09 -156.586153343142 53.4895436188457 -2.9274161406001 0.00370583820333677 DOPEY1 other 2.39235137461821e-09 1 2.1369804906213e-05 6.23952246253653 -2.9274161406001 7.74957739267198e-25 366.565416285453 34.7089931880752 10.5611077307593 4.49004063038152e-22 -163.465840898962 80.8673240564022 -2.02140781590534 0.0442168226198478 LYRM2 other 1.18522036643525e-20 1 6.93845978612857e-18 10.5611077307593 -2.02140781590534 6.90289298401298e-15 121.476456948524 16.4906493131672 7.36638410299156 2.16999123613354e-12 -69.238274849281 38.3249317131935 -1.80661182562383 0.0719444197964392 BCKDHB other 9.0938712171387e-11 1 3.03364774811469e-08 7.36638410299156 -1.80661182562383 7.57277584752595e-15 521.598474489334 73.9951512953684 7.04908991140859 3.87788504606359e-11 -326.408711118729 188.922910930705 -1.72773492378832 0.0857799703516391 KAT6A other 9.96728757051365e-11 1 5.24561510181021e-07 7.04908991140859 -1.72773492378832 1.66910419738145e-20 142.486255018946 25.5828787277402 5.56959427964782 6.11131257016898e-08 -253.418063494691 48.2981879536813 -5.24694764403423 3.10786138458318e-07 ZCCHC6 other 2.45441772224942e-16 0.00489239539161083 0.000730546304638 5.56959427964782 -5.24694764403423 1.00218662531091e-10 96.615986190862 31.3392097873647 3.08291073215941 0.00226377768332618 -291.688812954286 81.7975320212433 -3.56598549793083 0.000429169246285932 ULK2 other 1.14018772361622e-06 1 1 3.08291073215941 -3.56598549793083 0.04543812191493 127.892211091892 63.1014589226852 2.02677106481153 0.0436576982887228 -241.078491005975 252.059765893857 -0.956433844771139 0.339699273378195 GRHL2 other 1 1 1 2.02677106481153 -0.956433844771139 6.69829577836523e-07 1019.36937684264 202.940737210754 5.02299041017097 9.2225808515314e-07 184.492022217945 315.941582458961 0.583943464427983 0.559742291885713 TNPO1 other 0.00604990074701948 1 0.0102555099069029 5.02299041017097 0.583943464427983 6.64270210024591e-07 1611.61296362135 538.14367386577 2.99476337247316 0.0029985762238618 -1859.18653165804 842.68363202227 -2.20626871225251 0.0281980132885268 PLOD1 other 0.00600168134757218 1 1 2.99476337247316 -2.20626871225251 0.0599762953288355 33.2353819020486 14.001113999713 2.37376696616639 0.0182998135020521 18.854293854294 42.0033419991391 0.44887604073696 0.653877182884964 P2RX5 other 1 1 1 2.37376696616639 0.44887604073696 7.28020872583883e-05 73.6495726495725 25.3736350973328 2.90260234164534 0.00400275325943153 -183.717948717948 76.1209052919984 -2.41350188904362 0.0164587470974917 ITGAE other 0.547981310793889 1 1 2.90260234164534 -2.41350188904362 4.02315363547141e-15 281.658075655472 44.8146122314131 6.28496067758099 1.43350260266374e-09 -241.078451379084 92.0932912792428 -2.61776344433269 0.00938635648760984 DIS3 essential 5.34033413572476e-11 1 1.84262424546397e-05 6.28496067758099 -2.61776344433269 5.74927426202717e-19 75.2542759567759 14.0686787178367 5.34906493112009 1.99035523980224e-07 -149.896581583361 28.9333306388594 -5.18075791046467 4.54086628861473e-07 PIBF1 other 8.28355435672875e-15 0.0071377877190735 0.00231199664655429 5.34906493112009 -5.18075791046467 5.04634948716008e-10 52.4227994102407 15.7335310138425 3.33191572598158 0.000987758153902755 -96.3062748163085 26.3981617692507 -3.64821898047798 0.000319033159067584 TDRD3 other 5.54391954659407e-06 1 1 3.33191572598158 -3.64821898047798 7.38618101480478e-22 84.0045561051805 10.1938257382691 8.24072907091349 7.30770262308493e-15 -31.7880825305908 16.1071048819526 -1.97354414487039 0.049445619508481 NUFIP1 other 1.10379089085243e-17 1 1.06670535189171e-10 8.24072907091349 -1.97354414487039 3.34674826486271e-07 134.15485079595 42.0125821002418 3.19320651313118 0.0015724181629425 -149.317031310748 64.9333022426417 -2.29954470439194 0.0222317114566096 PDS5B other 0.00309975824291584 1 1 3.19320651313118 -2.29954470439194 6.91752247369358e-18 280.790434744078 29.3120080816746 9.5793653563989 9.36235866565759e-19 125.422822614227 190.192082442964 0.659453437825621 0.510202086921562 OXCT1 other 9.78137677780272e-14 1 1.42279764641998e-14 9.5793653563989 0.659453437825621 0.608085501138088 3.56550454031579 6.71359993532351 0.531086834882122 0.595795206916673 -10.4330731920791 15.5275030778347 -0.671909265757747 0.502215977465166 EPYC other 1 1 1 0.531086834882122 -0.671909265757747 2.48828526737218e-05 -22.785555054604 55.6743228319898 -0.409265059646342 0.682673267168568 -405.769286644625 99.625586588162 -4.07294250945812 6.12384156029887e-05 CYLD other 0.196624301827749 0.921148247500156 1 -0.409265059646342 -4.07294250945812 6.08005720656122e-08 36.6363497452985 10.9136960035511 3.35691499317717 0.000905089813324639 -86.9216637445972 26.6422604179754 -3.26254838669588 0.00125073140213406 SLC27A5 other 0.000590191153040898 1 1 3.35691499317717 -3.26254838669588 1.69701307439183e-14 53.7196283578246 9.95815118801803 5.39453833784547 1.53182877558172e-07 -95.4761062109328 24.268084802738 -3.93422501145047 0.000106866341844358 ZNF324 other 2.21103833462512e-10 1 0.00179162693592038 5.39453833784547 -3.93422501145047 0.283553795637384 -2.60746820931569 6.06182519231501 -0.430145727828205 0.667431493041732 -22.9975232737405 14.5491419774539 -1.58067900563337 0.115117861105256 ZNF671 other 1 1 1 -0.430145727828205 -1.58067900563337 9.44106492248895e-12 25.6733556298774 5.39303975713022 4.76046103608531 3.14775308525891e-06 -39.2368243249249 11.9666088930547 -3.27885908828336 0.00117848716857158 ZNF416 other 1.12055999565021e-07 1 0.0336431849752472 4.76046103608531 -3.27885908828336 4.16367936555785e-09 48.2378051152842 8.35355833462847 5.77452184841056 2.11025422970968e-08 -9.01426296833836 20.1801048013019 -0.446690592397559 0.65545522538617 ZNF586 other 4.33605569129194e-05 1 0.000257788656701335 5.77452184841056 -0.446690592397559 3.73029245336698e-11 45.1436566575597 11.4815130268512 3.93185606740025 0.00010796359636066 -116.062199900309 28.0284021063271 -4.14087822274068 4.6698986729697e-05 ZNF446 other 4.32378198269767e-07 0.705668388472452 1 3.93185606740025 -4.14087822274068 9.72472107247354e-10 64.878241882297 28.0721021104869 2.31112873652808 0.0215736101006415 -297.930756662013 62.5615415992762 -4.76220292924271 3.11745881836322e-06 ZNF264 other 1.05104785351294e-05 0.0484390751197278 1 2.31112873652808 -4.76220292924271 1.5464398798286e-10 5877.46118011093 866.727205424547 6.78121229300975 7.7300694152971e-11 1923.82741967192 2104.55484244679 0.91412558174785 0.361481833300641 RPS5 essential 1.74268310057885e-06 1 1.03667960928549e-06 6.78121229300975 0.91412558174785 2.6754230706167e-05 779.884561261393 540.601425343127 1.44262394566642 0.150294124628873 -2166.61860666261 839.221857422881 -2.58169944872022 0.0103630794632686 FAT1 other 0.210743075272478 1 1 1.44262394566642 -2.58169944872022 7.77293591895397e-19 377.355864805795 50.0562856641494 7.53863095910969 7.49142314054945e-13 -178.08301910096 105.173449128443 -1.69323170987268 0.0915820766235208 YTHDC1 essential 1.11720407963125e-14 1 1.05771403321418e-08 7.53863095910969 -1.69323170987268 0.00247802945086521 -39.691877486675 63.1133750734625 -0.628898033744425 0.530056609318022 -449.002439756773 132.567382329751 -3.38697522622808 0.000834594936808552 CHMP2B other 1 1 1 -0.628898033744425 -3.38697522622808 0.0418044522322395 44.6674514902543 61.9335332072838 0.721215941947925 0.471398395439412 -236.366538971106 123.487709410007 -1.91408958916158 0.0566618600821191 SMAP2 other 1 1 1 0.721215941947925 -1.91408958916158 6.80727967466254e-52 476.01386415179 26.7215831701426 17.8138346489764 1.79034126534895e-47 -132.219609462562 73.0254377137425 -1.81059660307493 0.0713148155252438 PPIE essential 1.08412736098676e-47 1 2.84950715792938e-43 17.8138346489764 -1.81059660307493 1.32009328456477e-14 402.193655512334 54.9421757380498 7.32030812594482 2.82145828451207e-12 -99.3746166982302 108.77702069516 -0.913562589443594 0.361758783367435 ZMPSTE24 other 1.72496589494079e-10 1 3.93621645272279e-08 7.32030812594482 -0.913562589443594 3.76736105375105e-15 1823.90102742886 209.772958301722 8.69464320947168 3.8822299278242e-16 1349.40575459722 940.94091514896 1.43410253807871 0.152735421509962 STARD7 other 5.00230200717065e-11 1 5.76317032785502e-12 8.69464320947168 1.43410253807871 1.3838997052638e-36 269.814307411621 20.7735409529644 12.9883638048292 4.83581136178327e-30 -67.496814253336 45.6181734199274 -1.47960361393714 0.14019433619606 NOA1 other 2.19043645349154e-32 1 7.62655809866839e-26 12.9883638048292 -1.47960361393714 1.00851042323243e-14 138.267876231587 29.6239830370836 4.66743030667082 4.89742037485076e-06 -288.561309753322 65.0535216232273 -4.43575232444129 1.35746442944677e-05 REST other 1.32276227111166e-10 0.208289342054312 0.0515698365471785 4.66743030667082 -4.43575232444129 0.291338259351132 6.61356631537082 14.5625310097263 0.454149509515455 0.650083399397986 -43.2921554981109 33.0322967142252 -1.31060083023132 0.191098195410486 HAL other 1 1 1 0.454149509515455 -1.31060083023132 0.105698285939719 132.754600105609 82.6448162737625 1.60632700381179 0.109366618578703 -151.720561355052 177.800838799201 -0.85331746677752 0.394236859791258 SSH1 other 1 1 1 1.60632700381179 -0.85331746677752 0.000227204195428198 3235.23628969428 1099.94622441803 2.94126768915999 0.00355432913490616 -6134.2510894785 3201.60244630042 -1.91599400374237 0.0564296655450391 GSTP1 other 1 1 1 2.94126768915999 -1.91599400374237 4.20862005801049e-10 4761.23479445699 951.577683520747 5.00351666176205 1.01595944430327e-06 -2499.35807591432 1745.56917271282 -1.43182986671907 0.153349095796394 APLP2 other 4.64210792398557e-06 1 0.011262926399546 5.00351666176205 -1.43182986671907 1.47104835488578e-10 176.162166240836 26.9529022344546 6.53592569395526 3.10682918490895e-10 -108.549962665953 115.462891145036 -0.940128569356544 0.347985751433213 FAM234B other 1.65934254431116e-06 1 4.08548037815527e-06 6.53592569395526 -0.940128569356544 4.18622190173971e-06 49.2062563442997 10.9228199460409 4.50490409870166 1.00099899890374e-05 -67.3528907574647 49.835252299527 -1.3515109816772 0.177697544513448 SLCO1A2 other 0.0354196235106197 1 0.10280072947302 4.50490409870166 -1.3515109816772 2.44965125037776e-37 894.352508600492 60.9984329397853 14.6618931913112 3.1031971980449e-36 -196.756472224239 258.65061879599 -0.760703659400211 0.44749544656171 WBP11 essential 3.88000261547334e-33 1 4.92229139553882e-32 14.6618931913112 -0.760703659400211 1.51987661490076e-17 849.625168146356 228.415330167973 3.71965037338586 0.000243170699695276 -1690.60268137387 325.044766480433 -5.20113798379103 3.9478530462911e-07 EIF3I essential 2.13588260692004e-13 0.00620957805651127 1 3.71965037338586 -5.20113798379103 0.0196648711249935 41.0689754099874 15.0075460017902 2.73655502405845 0.00662213080985294 21.2692212978 21.5427556759304 0.987302721051794 0.324381465087935 NKAIN1 other 1 1 1 2.73655502405845 0.987302721051794 0.000727686172113381 952.967783158461 422.65939497069 2.25469442889007 0.0249630176596087 -814.397677338353 601.462363484883 -1.35402932382954 0.176871942424981 COL16A1 other 1 1 1 2.25469442889007 -1.35402932382954 2.69722602922735e-10 250.585149313965 120.730972167406 2.07556640036413 0.0388913656160313 -747.312133440944 171.805327717065 -4.34976111259857 1.94121503980761e-05 TXLNA other 3.00524924176511e-06 0.296578833781806 1 2.07556640036413 -4.34976111259857 0.380432469746409 -1.56176815685005 1.74820091399911 -0.893357362042222 0.372464355311177 -7.0631533038851 5.76592485899063 -1.22498185054766 0.221653620359228 APOB other 1 1 1 -0.893357362042222 -1.22498185054766 1.48559802718314e-05 279.22771468778 58.231076963836 4.79516658881636 2.68004136647411e-06 23.3251989623774 203.557445173238 0.11458779580637 0.908856393337902 NCOA1 other 0.119947184714767 1 0.0288211648550626 4.79516658881636 0.11458779580637 2.44336952530893e-14 450.143936568716 53.6960315820176 8.38318816691596 2.77009405238365e-15 152.137367019063 200.383918181064 0.759229425195657 0.448370375131757 AGBL5 other 3.17198231775605e-10 1 4.06760610652015e-11 8.38318816691596 0.759229425195657 0.493607244240877 4.01706721659057 16.4970071800363 0.243502786460067 0.80779947346568 67.9006060316365 57.3981830525691 1.18297483335751 0.237852079742318 EFR3B other 1 1 1 0.243502786460067 1.18297483335751 0.00436913277011698 172.760167644703 53.9939386065421 3.199621514993 0.00153909213454099 214.081761253988 203.398753445355 1.05252248417296 0.293494022952583 KIF3C other 1 1 1 3.199621514993 1.05252248417296 0.100365993315846 402.553564788605 196.505189315546 2.04856455033454 0.041464420413943 -426.367915395101 732.659150849771 -0.581945799626716 0.561085200492784 RAB10 other 1 1 1 2.04856455033454 -0.581945799626716 4.71289690997561e-06 489.772327874125 98.1781792310296 4.98860675264316 1.08599620320886e-06 396.237773728129 366.052121462688 1.08246271636078 0.280005653803005 HADHA other 0.0396873048789046 1 0.0120122040036932 4.98860675264316 1.08246271636078 0.551763201413841 38.7193615250145 41.8579999776604 0.925016999036719 0.355773995221313 -84.8999408973615 156.206516489674 -0.543510877812667 0.587221638053275 MAPRE3 other 1 1 1 0.925016999036719 -0.543510877812667 6.04107074593937e-06 514.039689829343 110.264712241801 4.66186941749868 4.9069266158961e-06 779.69642845322 412.430925388668 1.89048972920362 0.0597514760999828 CAD other 0.0503342014551668 1 0.05166503033877 4.66186941749868 1.89048972920362 0.000376898932110643 1477.67293863234 485.368574867696 3.04443471445412 0.00256312656491441 -1124.88446298257 1110.58745997702 -1.01287336974419 0.312034211932494 CD59 other 1 1 1 3.04443471445412 -1.01287336974419 0.0376974946726288 -14.7551822895837 221.519484217677 -0.0666089592150029 0.946943238118317 -1071.2382696683 458.518613135488 -2.33630269083921 0.0202212768825714 CD82 other 1 1 1 -0.0666089592150029 -2.33630269083921 9.05742128973526e-17 94.646055010832 14.0422992862409 6.74006820973891 9.49505021857365e-11 -45.9153801166097 21.6982502123133 -2.11608676586067 0.035249339413169 AK6 essential 1.25119217696403e-12 1 1.2701528677386e-06 6.74006820973891 -2.11608676586067 0.412940534152608 -38.7206824201661 30.9090622646559 -1.25272912159625 0.21137629945356 -3.88845986726589 57.760793322198 -0.0673200564537868 0.946376187012442 FCN1 other 1 1 1 -1.25272912159625 -0.0673200564537868 5.29806924495641e-20 189.198249066393 18.5771799756682 10.1844439960316 1.047178226721e-20 -212.693288460535 173.788075930419 -1.2238658338429 0.222115025260723 MYNN other 7.74418781535279e-16 1 1.60877990971148e-16 10.1844439960316 -1.2238658338429 0.629143920082243 -21.1300651015979 33.8849183849192 -0.623583178261455 0.533452267333394 227.821961377436 316.379568913574 0.72009062456138 0.472121048466155 MECOM og 1 1 1 -0.623583178261455 0.72009062456138 1.39586758710766e-10 422.992222620594 93.081095027989 4.54434085131253 8.29643945719138e-06 -357.188550888509 147.023602176892 -2.42946401529977 0.0157688899910085 SCAMP1 other 1.57593450584454e-06 1 0.0857685911084445 4.54434085131253 -2.42946401529977 4.09132687641375e-15 340.494681891555 61.0822987392989 5.5743593302668 6.09220170477983e-08 -419.641533012304 104.25047739803 -4.02532001278141 7.4244824088868e-05 PREP other 5.43000903037633e-11 1 0.000728322713806429 5.5743593302668 -4.02532001278141 2.18133484958717e-09 85.9577377737441 19.3180004717733 4.44961878427025 1.26414880328627e-05 -89.7492914534528 32.9463548565189 -2.72410383012962 0.00687313100122843 HACE1 other 2.31526880935182e-05 1 0.128753555614707 4.44961878427025 -2.72410383012962 4.34248352717434e-16 382.648929471033 52.5092073008798 7.28727301630054 4.09789324154658e-12 -243.447084753297 119.174702126025 -2.04277485414527 0.0421194883866564 SEH1L essential 5.90230361013536e-12 1 5.69320308048067e-08 7.28727301630054 -2.04277485414527 5.34074946635595e-07 63.1592658377731 58.8344180968414 1.07350880455405 0.283994332431 -311.036352871523 87.7186098537729 -3.54584224932453 0.000460649644773491 WDR47 other 0.00486542276385027 1 1 1.07350880455405 -3.54584224932453 0.000158719847023973 -20.3631525754856 77.8527616614886 -0.261559797506305 0.793858791752738 -424.177039207722 114.188532042793 -3.71470787494457 0.000246865608252141 WDFY1 other 1 1 1 -0.261559797506305 -3.71470787494457 0.0163479507594972 11.5133296508766 5.23456678353583 2.19948089822623 0.0286821456051608 -0.558292928600074 7.69218503020593 -0.0725792380718548 0.942194094341449 OVGP1 other 1 1 1 2.19948089822623 -0.0725792380718548 2.22633211297248e-10 59.2436022594496 62.1050812606255 0.953925203170292 0.340981104746382 -442.93783186672 92.5044546471336 -4.78828650529691 2.78567399667207e-06 SLC25A24 other 2.4917109008388e-06 0.0433172306482507 1 0.953925203170292 -4.78828650529691 1.41606767480871e-06 221.101293266234 63.7772822504202 3.46677195177561 0.000613024019186372 -328.502185048048 118.073779410276 -2.78217726821963 0.00578174902914948 MAP3K4 other 0.0124613955383166 1 1 3.46677195177561 -2.78217726821963 0.541732060731164 3.17894064621647 13.8872244278975 0.228911159513662 0.819109984135968 -61.5440832294605 61.2319003889668 -1.00509836928971 0.315742782292257 PILRA other 1 1 1 0.228911159513662 -1.00509836928971 2.08963728829109e-05 750.253457604511 161.050944202528 4.65848530922635 4.99001039430763e-06 -330.651499784501 601.232347720422 -0.54995627071326 0.582800666647498 IGSF9 other 0.166356024520853 1 0.0524849293273276 4.65848530922635 -0.54995627071326 0.314219524947327 -9.55974122563663 6.57021595804242 -1.45501172057135 0.14686306131145 0.286816123027998 22.4719753150866 0.0127632804418151 0.989826365402374 ABCB1 other 1 1 1 -1.45501172057135 0.0127632804418151 2.20104691739983e-15 121.452815742408 22.6594464918023 5.3599197926722 1.7731207940761e-07 -123.217412570674 40.6988982398535 -3.02753681056693 0.00270125351852121 ZNF213 other 2.93949815818747e-11 1 0.00206568572509866 5.3599197926722 -3.02753681056693 7.87375443701996e-05 534.936911335856 174.007142256721 3.07422387609032 0.0023259244485282 -802.594626791588 466.805161248307 -1.71933537462467 0.0866951488412207 AKR1B1 other 0.590842010395153 1 1 3.07422387609032 -1.71933537462467 4.48094995923402e-09 573.390944951501 96.5416994732159 5.93930858976208 8.85250752469234e-09 -163.608113925237 325.917724951996 -0.501992071616646 0.616085264697639 CPNE3 other 4.65749938762784e-05 1 0.000110187161159845 5.93930858976208 -0.501992071616646 1.72331179114521e-23 325.445126087398 39.268568142122 8.28767488820924 5.60483586762134e-15 -174.692053320986 77.0687452217807 -2.26670426277571 0.0242055097300403 RRN3 essential 2.61271300655525e-19 1 8.19763293998297e-11 8.28767488820924 -2.26670426277571 1.96572982404959e-09 959.556271623363 199.772887044868 4.80323574343626 2.80175255982916e-06 -1755.05625805576 639.120954485448 -2.74604712259629 0.00650470448335077 CTTN other 2.09114338682395e-05 1 0.030076813729766 4.80323574343626 -2.74604712259629 0.540038034138865 60.9794884169886 55.2585698852228 1.10352997813097 0.270776012135709 73.5432888245388 130.615699289112 0.563050913671211 0.573865744850658 WNT11 other 1 1 1 1.10352997813097 0.563050913671211 3.25156876984063e-21 325.778246816363 31.0519190896117 10.4914046013134 8.92579876881905e-22 390.100764395237 152.895914196686 2.55141392394181 0.0112887848243978 MTIF2 other 4.82695383882841e-17 1 1.37760778197953e-17 10.4914046013134 2.55141392394181 9.54853632174142e-19 272.312666690977 45.1211938497954 6.03513877752177 7.58550266597949e-09 -380.431710086416 96.0227381513791 -3.96189191654448 0.00010340036678985 DDHD2 other 1.36935559390094e-14 1 9.46443167634261e-05 6.03513877752177 -3.96189191654448 0.115159845872719 76.7796648217169 51.4663913183314 1.49184084710383 0.136917031410728 -31.0632515435126 81.65246587602 -0.380432497784925 0.703925743835046 TTC39A other 1 1 1 1.49184084710383 -0.380432497784925 3.96540036980981e-05 59.3629085346557 58.7318707076253 1.01074438493832 0.313047067818301 -296.993304146007 94.2019926447634 -3.15272847004385 0.00180066645730278 EPS15 other 0.306723718604789 1 1 1.01074438493832 -3.15272847004385 2.10784993154534e-07 112.669539244194 26.276306628451 4.2878757976663 2.51660063788825e-05 -29.8865261513618 42.288824164104 -0.706723980675971 0.480349736220669 ORC1 other 0.00197758480577584 1 0.250099771393334 4.2878757976663 -0.706723980675971 0.000683500115693119 90.6333434747242 65.8966284532947 1.37538665637442 0.170151639204469 -196.736571765413 97.8351827027317 -2.01089798506524 0.0453301979822858 MGST2 other 1 1 1 1.37538665637442 -2.01089798506524 4.69430141102888e-20 502.379156546699 65.1385548409093 7.71247009967723 2.33940805757006e-13 -380.648550753729 146.575382063544 -2.59694735497062 0.00991739996346725 CHERP essential 6.86635467391194e-16 1 3.33950500218126e-09 7.71247009967723 -2.59694735497062 2.40469625665927e-16 79.8660389875044 26.4312749739674 3.02164912839678 0.00275258622662734 -226.999520894215 40.4801076539218 -5.6076807610027 5.01986834383117e-08 ATG16L1 other 3.28866260060721e-12 0.000795147145662857 1 3.02164912839678 -5.6076807610027 2.93373590654651e-08 168.458234697328 57.009376126006 2.95492156106025 0.00340136668162778 -252.082164355766 87.1010307540752 -2.8941352607813 0.00411008597483214 USP40 other 0.000290762565697824 1 1 2.95492156106025 -2.8941352607813 2.45311028633342e-19 466.685808778931 89.3750986175543 5.22165363728358 3.5279428398946e-07 -727.275463590482 157.051403343757 -4.6308116203114 5.64965544005531e-06 POMGNT1 other 3.55259431666806e-15 0.0873210744814949 0.00403596660883942 5.22165363728358 -4.6308116203114 1.89327050241772e-12 174.834862138544 30.1404642206989 5.80066918871397 1.83098844185958e-08 -72.3189043541636 52.9633228551574 -1.36545255198469 0.173239008842528 RAD54L other 2.30979001294962e-08 1 0.000224369323665473 5.80066918871397 -1.36545255198469 2.94107985105965e-13 625.975590812286 96.8777960115402 6.4614970259823 4.76697645897927e-10 -122.029551016704 170.235267449252 -0.716828850126968 0.474094770337309 MAST2 other 3.69223164502029e-09 1 6.22757804601052e-06 6.4614970259823 -0.716828850126968 4.05373735120582e-26 1414.96481030911 161.783797875774 8.74602295710474 2.90842213183231e-16 -1109.83649716654 436.083831304998 -2.54500721534508 0.0115105973549507 DNAJA1 other 6.24883612688378e-22 1 4.32336949896872e-12 8.74602295710474 -2.54500721534508 3.5916059312589e-15 2052.12839572358 260.610585485279 7.87430944872153 9.32178741662407e-14 668.642756992502 733.312947330737 0.911810925235078 0.362712890265022 B4GALT1 other 4.77108931908432e-11 1 1.33842223727888e-09 7.87430944872153 0.911810925235078 2.40594160368999e-20 773.827658767123 93.0280781818941 8.31821611163555 5.06658993687656e-15 -244.800823157056 268.509285645596 -0.911703379525456 0.362769409413128 CHMP5 other 3.53240346253764e-16 1 7.41546103161253e-11 8.31821611163555 -0.911703379525456 1.72580199107967e-42 508.311803615167 41.4601541401806 12.2602487655139 1.41489990921011e-27 -405.95504814326 119.667487370527 -3.39235875226745 0.000800906543352505 NFX1 other 2.74126388263095e-38 1 2.22294924736001e-23 12.2602487655139 -3.39235875226745 2.21142503244845e-08 110.945257005199 32.9067464935177 3.37150489876153 0.000857324172971701 -134.607009770446 52.5181925197247 -2.56305488274165 0.0109199950459638 DIMT1 essential 0.000220567532736408 1 1 3.37150489876153 -2.56305488274165 5.12414999769941e-15 991.619765873006 137.491079379647 7.21224802617848 5.42654669158734e-12 -1120.43405945073 364.324218132726 -3.07537628212941 0.00231564486600571 EIF2AK1 other 6.78232493695494e-11 1 7.51251123983351e-08 7.21224802617848 -3.07537628212941 0.391888434612855 29.0459996794854 37.9952246244069 0.76446448117133 0.445250756581286 -79.0566066592369 98.4397381972379 -0.803096474117352 0.422617614871297 EPDR1 other 1 1 1 0.76446448117133 -0.803096474117352 0.0068598550268407 47.2141628961235 38.1061710975433 1.23901618914337 0.21640368719002 -257.209443588923 106.567718506786 -2.41357746222693 0.0164554073683309 SNX10 other 1 1 1 1.23901618914337 -2.41357746222693 2.35545467749305e-10 269.817773790703 71.3071892775965 3.78387896822453 0.000189797006253944 -320.222783003309 120.028901633514 -2.66788064078974 0.00808948708611549 SEPHS1 other 2.63339832943724e-06 1 1 3.78387896822453 -2.66788064078974 1.30963348116548e-19 379.66319528623 48.5885333514899 7.81384349553718 1.34711185322059e-13 -95.1667405213399 88.6649461589458 -1.07332993075684 0.284110679863914 MRPL28 essential 1.90394515491838e-15 1 1.92866004025592e-09 7.81384349553718 -1.07332993075684 0.000444587396011811 315.651488573199 91.7311530698534 3.44105004689988 0.000670909904749882 -288.649979235976 323.034203546151 -0.893558564595581 0.372350957474253 ITPKC other 1 1 1 3.44105004689988 -0.893558564595581 0.319265669954325 -27.5191136532508 798.41281828711 -0.0344672743509924 0.97252991124313 -3329.27033286044 2301.23686957918 -1.44673083282785 0.149127977699273 CEACAM6 other 1 1 1 -0.0344672743509924 -1.44673083282785 0.0108486394881455 1206.78985532106 532.34221127253 2.26694376242737 0.024176002780967 -631.992680285086 888.362143279911 -0.711413340905898 0.477435555286614 FAT2 other 1 1 1 2.26694376242737 -0.711413340905898 1.80024400919302e-24 290.926736686303 32.3339267536558 8.99756899008283 4.01071090922606e-17 -119.946010873792 53.9582168448936 -2.22294245227903 0.0270387352421942 RBM22 essential 2.74825250443407e-20 1 6.01045136856617e-13 8.99756899008283 -2.22294245227903 0.000202691962468729 1177.97626282228 354.929735095266 3.31889990143006 0.00102705927022909 -1175.10181182205 739.238914786217 -1.58961032531936 0.113084283859904 TMED2 essential 1 1 1 3.31889990143006 -1.58961032531936 0.417986041941389 0.766786263454673 53.571892680279 0.0143132195838387 0.988590547416302 -196.878780112762 149.740022477425 -1.31480399732439 0.189679191989979 ERO1B other 1 1 1 0.0143132195838387 -1.31480399732439 9.12772938712574e-09 336.357242459734 66.9980192997351 5.02040576684726 9.33685726161896e-07 -240.245487996688 132.005348292713 -1.81996783542406 0.0698629571835822 ZFAND6 other 9.32397556894894e-05 1 0.0103797842177418 5.02040576684726 -1.81996783542406 0.327562700203064 -6.66014018259001 41.8504188087362 -0.159141542000524 0.87367502794775 -90.9684100122435 70.160407502433 -1.29657756062903 0.195871448116092 HSD17B2 other 1 1 1 -0.159141542000524 -1.29657756062903 0.0267296648967919 -47.2782078228328 19.7495870632101 -2.39388335925786 0.0173512576843415 -128.926286076793 66.4783895905695 -1.93937137874174 0.0534938866234375 LAT2 other 1 1 1 -2.39388335925786 -1.93937137874174 5.06707319328093e-14 216.004578625898 32.1569394036649 6.71719954173501 1.07368321014171e-10 -29.4564152286734 56.8446442213127 -0.518191566367995 0.604744325171679 ZW10 essential 6.51980307779457e-10 1 1.43325971721817e-06 6.71719954173501 -0.518191566367995 4.67927752293372e-20 124.802672269675 18.7935404306108 6.64072172725888 1.70025173746187e-10 -100.788350459975 33.3167263120901 -3.02515767953469 0.0027236804200247 ALG9 other 6.84484716054744e-16 1 2.25759425700187e-06 6.64072172725888 -3.02515767953469 0.433367571448298 -16.3438605563041 19.4759557113751 -0.839181439848848 0.402109880847879 -51.3789293569984 41.7613187456598 -1.23029949484864 0.219655790366295 MYBPC2 other 1 1 1 -0.839181439848848 -1.23029949484864 0.0227177238300549 11.8513388908917 14.1422126870619 0.838011643095569 0.402770910521589 -55.7695139114905 28.9592062182171 -1.92579566895753 0.0551877335124647 NOX4 other 1 1 1 0.838011643095569 -1.92579566895753 2.60371023428177e-17 28.020029831664 26.1074104875973 1.07325963427033 0.284112919546114 -239.386295464604 38.4232367317935 -6.23024804327645 1.77975987578791e-09 ACOX3 other 3.64311135980706e-13 2.83319974626677e-05 1 1.07325963427033 -6.23024804327645 2.9273179429268e-19 370.299555309566 53.1134644975762 6.97185843198881 2.41713122085425e-11 -242.680280937477 94.6782794778148 -2.56320966409558 0.0109152463256773 MTMR2 other 4.23290174547216e-15 1 3.28971559158263e-07 6.97185843198881 -2.56320966409558 0.111462329225772 327.51510444823 235.770946611484 1.38912410182552 0.165927067202804 -431.13473579409 491.103137883448 -0.877890411476885 0.380775137190103 PPP1R15A other 1 1 1 1.38912410182552 -0.877890411476885 0.109731103835512 40.0116462951152 26.3771280520919 1.51690685263751 0.130447281344313 -39.0672925827416 54.9214335183312 -0.711330533091458 0.47748677367239 HSD17B14 other 1 1 1 1.51690685263751 -0.711330533091458 0.169314901300859 5.98951569578808 10.441748939493 0.573612306759683 0.566702416654357 -71.4492163209973 44.6264189269555 -1.60105197860365 0.110521901310704 ACHE other 1 1 1 0.573612306759683 -1.60105197860365 2.06127314279411e-07 30092.927583861 5869.50703871933 5.12699403635556 5.5839780565508e-07 -2561.68364643995 12225.9903774066 -0.20952770019956 0.834192584906912 FTL other 0.00193553548108367 1 0.00629370166753841 5.12699403635556 -0.20952770019956 1.7124345669413e-06 303.342054390632 65.1653475071658 4.65495951444554 5.06183225799328e-06 -348.417251301815 278.506609786062 -1.25101968520408 0.211998334038278 SRRT essential 0.0149735278533347 1 0.0532150425282833 4.65495951444554 -1.25101968520408 3.02303954371518e-14 218.325871052236 42.7445792563418 5.10768557909817 6.13040232765262e-07 -353.673030122048 89.0355546431635 -3.97226738845507 9.11445705365059e-05 BAX og 3.9154408170199e-10 1 0.00689608957837643 5.10768557909817 -3.97226738845507 4.73244498863672e-19 189.583829803714 22.842405156304 8.29964395195895 6.21542958475334e-15 -79.5837926894594 53.4621531222111 -1.48860059016957 0.137833075126861 NLK other 6.82513216261187e-15 1 9.083850338117e-11 8.29964395195895 -1.48860059016957 2.85866281480669e-19 526.421663689856 76.0875529144727 6.91863049244845 3.64147709915219e-11 -626.98238571829 172.528371867906 -3.63408278261811 0.000337088731898541 PIGS other 4.13448402905492e-15 1 4.92946754912231e-07 6.91863049244845 -3.63408278261811 0.674831094301311 -82.7701452956394 135.139257661718 -0.612480390434217 0.540729791333767 69.2272811919355 225.193728006932 0.307412119354428 0.758764083950476 ADAMTS2 other 1 1 1 -0.612480390434217 0.307412119354428 0.152600467149193 134.458260073044 142.655328438696 0.942539346722167 0.346791530797465 -342.025654835451 331.090044604087 -1.03302911219949 0.302550196828581 TMPRSS11E other 1 1 1 0.942539346722167 -1.03302911219949 1.73861130443879e-06 274.288602008131 67.1290728786292 4.08598823499396 5.78013176080809e-05 -205.811158647671 138.86409901979 -1.48210487880197 0.139469985921939 ATXN7L3 other 0.0151937241894906 1 0.555412860896049 4.08598823499396 -1.48210487880197 6.38640103772108e-09 181.523592834379 29.0395679429176 6.25090542638912 1.56426201626288e-09 35.7870867236027 63.5190069722914 0.563407528383023 0.573619874028908 PGS1 essential 6.58629539020175e-05 1 2.00663531446202e-05 6.25090542638912 0.563407528383023 5.97033622975735e-14 661.453578227812 81.8018109759958 8.08605054504125 2.06770411636029e-14 44.8607605325442 181.264494581264 0.247487852688284 0.80471809217252 PSMC5 essential 7.66412061813951e-10 1 2.99837773913406e-10 8.08605054504125 0.247487852688284 7.10564717623341e-19 156.820030019472 20.6352212303923 7.59962921010518 4.77463177641795e-13 -74.5350780209743 34.5686227370768 -2.15614832525657 0.0319456383207869 UIMC1 other 1.02214734630118e-14 1 6.77520249073707e-09 7.59962921010518 -2.15614832525657 0.459708283059015 -6.38390866640693 6.53794989899039 -0.976438908990836 0.329714621369491 -14.133106990233 11.7595938500941 -1.20183631938274 0.230472274690737 CETP other 1 1 1 -0.976438908990836 -1.20183631938274 0.358815952083324 -356.033133987834 909.723239294468 -0.391364228821893 0.695833313660755 -2194.74867068082 1627.58519204091 -1.34846930373501 0.178625115063249 MMP2 other 1 1 1 -0.391364228821893 -1.34846930373501 0.545713647753598 -11.0593374536505 32.0501367972391 -0.345063658343048 0.730312218115131 -60.1241559332246 57.4305837169227 -1.04690135537501 0.296071077764631 MT3 other 1 1 1 -0.345063658343048 -1.04690135537501 2.37305399579078e-06 141.509030765627 63.7964691834845 2.21813264239803 0.0273688253312817 -288.201402867234 114.569786236106 -2.51550964992906 0.0124604660160182 LPCAT2 other 0.0204675907136955 1 1 2.21813264239803 -2.51550964992906 0.238097657523984 39.6391023648292 36.8820401456683 1.07475351711217 0.283434064684427 -27.7875307261137 66.0888628225503 -0.42045708670648 0.674482335176728 GNAO1 other 1 1 1 1.07475351711217 -0.42045708670648 8.51388457782426e-20 177.908717770841 35.6947846019088 4.98416560724469 1.10687939398981e-06 -268.542183746354 64.0455980271055 -4.1929842490143 3.72387059654408e-05 OGFOD1 other 1.24132437144678e-15 0.56438982761222 0.0122299104241934 4.98416560724469 -4.1929842490143 6.50028983686048e-14 368.552621846777 104.943046348216 3.51192989599204 0.000520968359347388 -591.678176580502 164.860063926991 -3.58897214089719 0.000393908577142625 SH3BP2 other 8.33402159983883e-10 1 1 3.51192989599204 -3.58897214089719 2.64277562084484e-17 426.994001965396 65.3358192631096 6.5353738084446 3.13341295330396e-10 -113.548773577445 102.932818491859 -1.10313479453033 0.270947255794974 NOP14 essential 3.69697881599985e-13 1 4.11918466841338e-06 6.5353738084446 -1.10313479453033 1.55674773773809e-21 542.550954401537 201.966182288019 2.68634554683921 0.0076700364218372 -2021.85488684729 317.278360803554 -6.37249537512311 7.95707420159403e-10 ADD1 other 2.3169076580756e-17 1.26756192031393e-05 1 2.68634554683921 -6.37249537512311 7.33195574121243e-20 96.9491958302206 14.5931919956972 6.64345373231615 1.69257741547739e-10 -92.3763391832006 27.0363309968773 -3.41674834480574 0.000731757216826061 L2HGDH other 1.06965902308548e-15 1 2.24774280775397e-06 6.64345373231615 -3.41674834480574 0.0589334075640396 28.3441737651516 20.8801796880437 1.35746790442527 0.17577456361779 -45.314688903671 39.8783334372221 -1.13632353706573 0.256836254254248 TXNDC16 other 1 1 1 1.35746790442527 -1.13632353706573 0.840590981805116 15.5956410504691 35.6104788905785 0.437950893566761 0.661773336761274 37.4922507434268 68.0360326204219 0.551064624132316 0.582046772812299 NID2 other 1 1 1 0.437950893566761 0.551064624132316 1.51803759204179e-08 205.121140456341 33.1648989341206 6.184886643671 2.28083081864521e-09 134.452311432309 155.514423276889 0.864564897578151 0.388042269341112 GMCL1 other 0.000152836024766767 1 2.90737504452705e-05 6.184886643671 0.864564897578151 7.34901253022293e-12 1083.05072952036 179.596602908574 6.0304633382832 5.3366765471957e-09 -1031.79976951547 427.379140984264 -2.41424924749301 0.016430637365082 SF3B2 essential 8.76002293602573e-08 1 6.70393307858724e-05 6.0304633382832 -2.41424924749301 1.44957083341806e-11 234.961376954245 34.2043743298222 6.86933708211076 4.41064610900153e-11 -287.836053370104 210.33861230224 -1.36844134426686 0.17230736053745 KLHL42 other 1.7097687980166e-07 1 5.95790076403927e-07 6.86933708211076 -1.36844134426686 9.12655670667264e-10 5695.58195002016 1055.01406636252 5.3985838972341 1.46416760024983e-07 -7575.4824475104 3165.67813658708 -2.39300463302234 0.0173894633785839 GNAS other 9.88223560198513e-06 1 0.00171395459285245 5.3985838972341 -2.39300463302234 2.06595536233911e-39 654.524284511283 42.2124819407361 15.5054679189486 5.40817712109306e-39 -166.86590706323 273.482393701752 -0.610152283679391 0.54228578335344 DNM1L essential 3.2763986091336e-35 1 8.58926690372e-35 15.5054679189486 -0.610152283679391 0.0146478439770834 1015.2897326105 374.662141237946 2.70988077219602 0.00715996635943399 -1295.93374416268 2303.97182858176 -0.562478120646295 0.574255285059509 PTHLH other 1 1 1 2.70988077219602 -0.562478120646295 0.00661175617280022 45.476504396466 15.0373856565613 3.02422943955174 0.00273087380715777 80.9852553671823 44.6878348198892 1.81224388457366 0.0710511017306924 PHACTR3 other 1 1 1 3.02422943955174 1.81224388457366 1.24078875557847e-42 462.171883598671 27.6823402061657 16.6955495870877 1.61017230442093e-43 302.373766647028 169.554539782276 1.78334220384369 0.0756496987166392 ERGIC2 other 1.97111701711195e-38 1 2.56114006741192e-39 16.6955495870877 1.78334220384369 3.00199345888432e-05 197.43066321335 54.9430939637548 3.59336631722255 0.000387860436975233 -314.668895512395 169.879128012388 -1.8523105174489 0.0650726075680292 TFAP2C other 0.235086107765231 1 1 3.59336631722255 -1.8523105174489 1.13688503427793e-11 234.003163603493 33.808938627037 6.92134012797317 3.25245179774138e-11 -73.8306834774146 102.478433764572 -0.720450935530773 0.471870659912379 AURKA essential 1.34595819208164e-07 1 4.40934890219798e-07 6.92134012797317 -0.720450935530773 0.307354454887287 -14.5733434390872 14.5054712290825 -1.00467907653139 0.315950940979802 -62.6986230135298 44.849618505847 -1.39797450017007 0.163268106813085 CASS4 other 1 1 1 -1.00467907653139 -1.39797450017007 1.3416004313857e-12 82.8006533521421 11.3618026476049 7.28763347861856 3.45644258187956e-12 8.88338654193594 28.9260426535575 0.307106874187071 0.758997881019451 AAMDC other 1.64507044896515e-08 1 4.81136807397635e-08 7.28763347861856 0.307106874187071 0.056196624247038 37.5747942631703 28.6215043056391 1.31281688977358 0.190355291875483 129.975476462431 53.898581009973 2.41148234381868 0.0165531250914927 RFX2 other 1 1 1 1.31281688977358 2.41148234381868 9.95788378070368e-14 151.237657741462 19.974243517195 7.57163381988748 5.91503800337143e-13 -42.26171086203 43.1688037482066 -0.978987305474864 0.32846587005267 METTL2A other 1.26923186668849e-09 1 8.3733277975726e-09 7.57163381988748 -0.978987305474864 0.0125214718176696 11.6195601841739 42.2572712032964 0.274971853442052 0.783545847012145 -228.152280831604 87.9864519925959 -2.59303876522721 0.0100261034273879 SULT2B1 other 1 1 1 0.274971853442052 -2.59303876522721 3.7040692195185e-42 127.959247736834 8.60302477369831 14.8737509309562 4.68963844978798e-37 -56.4003710993022 26.57080225891 -2.12264464391133 0.0346837336809317 ALG6 other 5.88280273443928e-38 1 7.44245621981352e-33 14.8737509309562 -2.12264464391133 4.76738210854031e-23 415.414103461291 47.8205592241538 8.68693528894302 3.48318811087403e-16 -414.915764126328 122.24876107054 -3.39402837699856 0.000790909221531744 CNOT3 other 7.20065393673929e-19 1 5.17288266345902e-12 8.68693528894302 -3.39402837699856 5.97513774652177e-07 70.2819431927201 14.731946636182 4.77071665601245 2.99830658790701e-06 -52.506882867692 44.5967210932093 -1.17737092729194 0.24007667074172 PTPN4 other 0.00541765739477129 1 0.0321178601696599 4.77071665601245 -1.17737092729194 9.52358802598583e-15 678.218874974432 83.8195712350647 8.0914142721206 1.99566089941565e-14 -51.7740490448688 259.853480229351 -0.199243238917455 0.842221885755495 DDX18 essential 1.24987569253038e-10 1 2.89450656851246e-10 8.0914142721206 -0.199243238917455 2.37752163348441e-10 167.028889220663 76.2099970053048 2.19169263592854 0.0292527428279061 -529.420912619777 127.907602318951 -4.13908870951714 4.65946551842981e-05 GNA11 other 2.65735592974553e-06 0.704185023800297 1 2.19169263592854 -4.13908870951714 8.72016606763119e-05 135.63537931492 53.3121747604172 2.5441726945948 0.0115071081266203 -111.030281984151 78.8412744540057 -1.40827609336685 0.160191292264099 ASAP3 other 0.651047598609345 1 1 2.5441726945948 -1.40827609336685 3.22133194980142e-14 217.303540134696 29.0209699288638 7.48781107824274 1.04128494730736e-12 -267.956592596979 128.107960007409 -2.091646706274 0.0374221414643721 EDEM2 other 4.17001420901794e-10 1 1.46623333430349e-08 7.48781107824274 -2.091646706274 3.13271058926086e-07 126.45208039138 23.6346663109397 5.35027991204809 1.88529589553888e-07 336.975215217995 119.467489299016 2.82064365121609 0.00515100625331534 DNMT3B other 0.0029062156136573 1 0.00219241059692216 5.35027991204809 2.82064365121609 0.168099567323812 -5.6883539740683 3.26873888959971 -1.74022892809431 0.0830347430438609 -15.7988807488808 14.8009918924312 -1.06742040423385 0.286799511931596 REM1 other 1 1 1 -1.74022892809431 -1.06742040423385 1.70563081297397e-13 846.272748415611 104.643518009799 8.08719703342125 2.54367887372343e-14 314.22444037444 473.830401867364 0.663158039534995 0.507833098764906 TPX2 essential 2.15830523073726e-09 1 3.68401011281365e-10 8.08719703342125 0.663158039534995 0.000487735806303625 244.133854956434 62.4344739070154 3.91024124460512 0.000117196990878816 53.7909601383426 269.501133233602 0.199594560115326 0.841950751166645 FER1L4 other 1 1 1 3.91024124460512 0.199594560115326 2.20162080735184e-16 186.932997434535 21.5957751762515 8.65599849548823 5.7162676287024e-16 -119.258445235399 97.8514552397732 -1.21877027728581 0.224062112246938 PDRG1 essential 3.0135785611032e-12 1 8.46464910458252e-12 8.65599849548823 -1.21877027728581 0.0906553047783031 124.070589456036 81.5820463268982 1.52080751883677 0.129487074138451 -396.072184560045 339.044839287738 -1.16820000974535 0.243764252492749 EPB41L1 other 1 1 1 1.52080751883677 -1.16820000974535 0.0343613628424781 22.5218792778902 14.1029016821081 1.59696775780994 0.11144692017779 -28.3317797059483 25.3960733133445 -1.11559686241184 0.265590336475964 SLC15A1 other 1 1 1 1.59696775780994 -1.11559686241184 2.17447617267823e-07 294.334407930038 99.6332707047644 2.95417791514861 0.00341244093055676 -538.10229025831 179.4165416665 -2.99917881183184 0.00296064242643896 DOCK9 other 0.0020374841737995 1 1 2.95417791514861 -2.99917881183184 2.93693447865424e-13 318.272066457653 62.6827470266108 5.07750667536215 7.21511262420008e-07 -430.094831647527 123.73184213938 -3.47602382871694 0.000594477388112872 ANKRD10 other 3.6873212379504e-09 1 0.00807659707152957 5.07750667536215 -3.47602382871694 9.35043810395617e-14 115.745920785211 16.2610245437581 7.11799680725785 1.08362204871812e-11 2.25194824166623 28.3613589112972 0.0794019866505484 0.936774440178747 TGDS other 1.19330291082689e-09 1 1.48900505714357e-07 7.11799680725785 0.0794019866505484 0.00137295864780421 61.6516764450157 17.6700991594096 3.48903964198669 0.000565564352232728 2.9530420042814 41.7660467405739 0.0707043695713878 0.943685190834118 DOCK3 other 1 1 1 3.48903964198669 0.0707043695713878 0.06092070748843 24.7998809733732 11.389087008447 2.17751264477827 0.0303082133410878 -4.78800035267194 26.8967244938661 -0.178014254254783 0.858845266158591 C3orf18 other 1 1 1 2.17751264477827 -0.178014254254783 6.70701991759387e-28 282.837207283533 43.1400521096436 6.55625557810364 2.74758526757281e-10 -364.353404087494 75.4309485511951 -4.83029063117517 2.2752008643685e-06 COQ9 other 1.04227089519409e-23 0.0354294278599463 3.61856979739339e-06 6.55625557810364 -4.83029063117517 2.42858585951437e-07 268.511334173782 54.115200282272 4.96184681518671 1.230139823738e-06 -164.598692347945 157.407467237979 -1.04568541274534 0.296631279194307 TMEM40 other 0.00226829919278643 1 0.013554910717769 4.96184681518671 -1.04568541274534 0.00211260665783393 26.5061189634074 8.61916871829059 3.07525236246498 0.00231737974845052 -17.7003321722993 22.3157232714987 -0.793177615484499 0.428365683566388 KIF9 other 1 1 1 3.07525236246498 -0.793177615484499 8.18658221726605e-05 147.214153164819 37.3337347856433 3.94319384358595 0.000102520846802604 -22.810027382636 82.4924116671253 -0.276510613784446 0.782367456540545 ARHGAP28 other 0.6132568738954 1 0.960620334540399 3.94319384358595 -0.276510613784446 8.76973183969322e-12 193.007252696893 33.5006653521805 5.76129610167072 2.25528197122355e-08 -400.688801964459 122.42502264491 -3.27293222666289 0.0012019814565742 CRLS1 essential 1.04272111573952e-07 1 0.000275099294849848 5.76129610167072 -3.27293222666289 9.98945757757168e-20 434.647759832881 48.0301501196127 9.04947743761885 3.07408886046568e-17 -23.2630991023445 112.886369158436 -0.206075359458986 0.836889091289651 PPP1R13B other 1.45426523414288e-15 1 4.61082588181248e-13 9.04947743761885 -0.206075359458986 2.50692879083732e-11 869.769341034992 130.009224226191 6.69005869554118 1.2666688668538e-10 -727.817842418086 465.815059640977 -1.56246095387952 0.119342128810134 ATRN other 2.92683936330257e-07 1 1.68846959951611e-06 6.69005869554118 -1.56246095387952 8.34102005379524e-09 233.852345708143 37.1835770592301 6.2891298848316 1.26805316975688e-09 125.232749161076 134.767050285574 0.92925347030825 0.353581670573144 SMOX other 8.54037043308095e-05 1 1.63325248264686e-05 6.2891298848316 0.92925347030825 0.1659038761854 -66.8618178310468 39.1985397322924 -1.70572215923556 0.089205594932492 -170.342376409691 141.7185980416 -1.20197616095305 0.230422031768986 SIGLEC1 other 1 1 1 -1.70572215923556 -1.20197616095305 1.87751517935048e-27 706.638500962447 58.4163481894653 12.0965880761763 3.18013126810406e-27 -280.65556620538 233.317929406008 -1.20288898037063 0.230069139329419 NSFL1C other 2.91221379469053e-23 1 4.99376013030381e-23 12.0965880761763 -1.20288898037063 7.6983911684832e-05 297.326743713182 74.6046256089545 3.98536607195968 8.65985731747233e-05 -313.748608938084 271.430777658805 -1.1559065322079 0.248733689767 SLC4A11 other 0.578149176753088 1 0.816884340757165 3.98536607195968 -1.1559065322079 1.16839289132875e-08 174.754526053326 30.9234887103413 5.65119051379497 4.01722466666174e-08 -177.243194978898 112.507589443137 -1.57538878804686 0.116329084742359 C20orf194 other 0.000118498407038562 1 0.000484356778059406 5.65119051379497 -1.57538878804686 2.39126771648254e-19 95.3957039681175 10.3671785311547 9.20170359577014 9.48413266170586e-18 -73.4728502154033 38.5038107302964 -1.90819684654204 0.0574146571684555 ZNF343 other 3.46422954086825e-15 1 1.42925879211907e-13 9.20170359577014 -1.90819684654204 0.000309743075752192 80.0022076949482 20.3384453151076 3.93354587607155 0.000106310459637798 -16.9790620026838 72.5423138320087 -0.234057353643329 0.815116525872722 EBF4 other 1 1 0.994534349911601 3.93354587607155 -0.234057353643329 0.535644671732449 46.033162230474 51.9978285918747 0.885290087626223 0.376782139808005 -89.512341248791 185.463674428097 -0.48264082723916 0.629738981001386 CPXM1 other 1 1 1 0.885290087626223 -0.48264082723916 2.46927580920901e-22 737.587611835919 74.0850971326638 9.95595120183381 4.20404275622017e-20 -601.355297294312 267.847633435372 -2.24513948315101 0.0255657082758264 MAVS other 3.70786455510824e-18 1 6.43933228970244e-16 9.95595120183381 -2.24513948315101 7.30947095982729e-06 191.642077387809 43.3940692577966 4.41631957236592 1.44832545990379e-05 -212.742615880524 156.311496110946 -1.36101707918863 0.174630696688481 LZTS3 other 0.0605151100764102 1 0.146729852342853 4.41631957236592 -1.36101707918863 0.00587493184997918 -2.02678041417215 8.44992221925352 -0.239857878165321 0.810622431335066 -34.564231723795 13.0211437113612 -2.65446972170632 0.00841481413885677 F11 other 1 1 1 -0.239857878165321 -2.65446972170632 1.11291226048955e-20 620.553698854244 71.8246408033083 8.63984409686962 5.16866533303426e-16 -751.407436945621 238.980948227337 -3.14421481092637 0.00185266580868521 XRN2 essential 1.64087783686579e-16 1 7.66047889009008e-12 8.63984409686962 -3.14421481092637 0.0243661446553865 45.1687458561967 27.7841855274259 1.6256998360312 0.105184466124236 -152.158967496308 92.4860408664858 -1.64521008868751 0.101094456308335 KIZ other 1 1 1 1.6256998360312 -1.64521008868751 0.0782484610385968 343.825807304848 159.254523357627 2.15897043334049 0.0317302025632227 8.09851191914403 332.305223683735 0.0243707030222661 0.980574852189516 DYNLL1 essential 1 1 1 2.15897043334049 0.0243707030222661 0.611251192212892 -67.1474088369322 97.7159272665327 -0.687169540476028 0.492561368102588 -182.240318881289 206.435424366639 -0.882795767443581 0.378126160295032 TESC other 1 1 1 -0.687169540476028 -0.882795767443581 1.40520483920717e-20 524.895830435141 56.7045720514025 9.25667563383294 6.76280646070467e-18 -414.75026764167 193.634492713517 -2.14192348599428 0.0330944000350656 SNX5 other 2.06888308476472e-16 1 1.02050749492033e-13 9.25667563383294 -2.14192348599428 1.5129485763683e-07 1425.88423220786 275.689562380602 5.17206462187118 4.49616802711979e-07 -539.592604416105 583.622714840494 -0.924557236542065 0.356015762305695 RPL6 essential 0.00143155194295969 1 0.00510225147717554 5.17206462187118 -0.924557236542065 0.172461437378583 -8.56599708952046 4.56750943853677 -1.87541967997873 0.0618022718157306 -2.69269744446825 18.0199834642463 -0.149428408178668 0.881325925877923 SIRPG other 1 1 1 -1.87541967997873 -0.149428408178668 1.18949264167932e-10 161.201531407562 33.0021749072927 4.88457296709678 1.78137347208098e-06 -238.756082090757 69.1908073008953 -3.45069079845333 0.00064907053258694 MAPKAPK5 other 1.34793306155101e-06 1 0.0194062826048502 4.88457296709678 -3.45069079845333 0.282313262499466 -22.3507172128496 17.3480488735824 -1.28837066206824 0.198711810556845 -46.9775115393477 35.9155777724564 -1.30799821283607 0.19197824513509 P2RX7 other 1 1 1 -1.28837066206824 -1.30799821283607 6.13063918232106e-16 189.729765345153 22.9199526169699 8.27793008632474 6.13354083374024e-15 -83.1550981681838 80.464005983787 -1.03344467071325 0.302334505040104 ESF1 essential 8.30088545286272e-12 1 8.96478328259473e-11 8.27793008632474 -1.03344467071325 3.29125818600865e-08 118.208138354954 26.9768513298769 4.38183600115104 1.68625702916691e-05 -258.967856856062 91.0580255364503 -2.84398717554443 0.00479607248848931 RBBP9 other 0.000324913008122774 1 0.169907258258857 4.38183600115104 -2.84398717554443 1.02346302877326e-09 580.266528513772 119.187962239915 4.86849944917883 1.90906410845237e-06 -676.97629741617 246.754234932259 -2.74352453404505 0.00648241207277649 ANAPC5 essential 1.10441895434923e-05 1 0.0207629812435279 4.86849944917883 -2.74352453404505 1.10257548865739e-08 187.02878367271 31.4758348059212 5.94198008808732 8.59303960333751e-09 -50.584422331596 113.641764718783 -0.445121760092092 0.656585789840344 SLC23A2 other 0.000112054746912251 1 0.000107017715219965 5.94198008808732 -0.445121760092092 0.00963414815031921 15.8508419459265 41.8547170958026 0.378711004297197 0.70519900195081 -250.360831567796 88.4155321534834 -2.83163857605004 0.00497826460409953 SLC8B1 other 1 1 1 0.378711004297197 -2.83163857605004 9.227637363577e-15 535.753601836199 71.1198609081009 7.53310812191387 7.35289120131887e-13 -521.877629210014 256.774333388945 -2.03243689632915 0.0430808411806862 TMEM230 other 1.21140423309039e-10 1 1.03859588218629e-08 7.53310812191387 -2.03243689632915 0.0215942967792814 15.4062835955154 8.8901027942305 1.73297024253913 0.0842427256852694 -48.903685664207 29.9929556982726 -1.6305057146143 0.104160599207865 DZANK1 other 1 1 1 1.73297024253913 -1.6305057146143 0.478379234189602 1.94280914713129 4.55074533654886 0.426921087305812 0.669775775141636 -14.5722770993777 14.9831537749272 -0.972577423837362 0.331630653858225 CFAP61 other 1 1 1 0.426921087305812 -0.972577423837362 0.0168405254566343 13.4034953963978 9.41550141709767 1.42355619766126 0.155725260026811 -40.4699970299341 20.0280697986445 -2.02066387009861 0.0442979771891293 LHX5 other 1 1 1 1.42355619766126 -2.02066387009861 8.98876750196299e-17 53.0712835093419 6.79638231264828 7.80875487398267 1.33503947188526e-13 -60.7303682642838 23.9451800039029 -2.5362251715955 0.0117780142638153 TASP1 other 1.24197800574623e-12 1 1.91177652373969e-09 7.80875487398267 -2.5362251715955 0.316800652550082 126.585861910975 131.105626542842 0.965525776802647 0.335142348676737 -239.384655073033 277.174347576682 -0.863660930984265 0.388537919626911 OAS1 other 1 1 1 0.965525776802647 -0.863660930984265 2.01904390841721e-09 876.778661507597 169.905929567155 5.16037706124347 4.79237743998321e-07 -792.840044903028 354.860016193262 -2.2342332433171 0.0262895034572954 GCN1 other 2.14604177025665e-05 1 0.005424971262061 5.16037706124347 -2.2342332433171 1.65894454904371e-07 6360.25650257952 1316.47607534148 4.83127389985398 2.28128050326991e-06 -3969.12858865959 2749.54925118769 -1.44355609812957 0.150027438551302 RPLP0 essential 0.00156504828756784 1 0.0246469545573282 4.83127389985398 -1.44355609812957 0.0210314537001797 558.558290341072 282.490548392003 1.97726364128112 0.0490326700007831 -741.838337154867 590.000601110321 -1.25735183279272 0.209716784579692 PXN other 1 1 1 1.97726364128112 -1.25735183279272 0.0871008171970462 2.01593699245248 1.39613126696376 1.44394516486738 0.149918041934847 -3.33762658832521 2.91591450201188 -1.1446242974622 0.25338224950419 SIRT4 other 1 1 1 1.44394516486738 -1.1446242974622 9.73753925201071e-16 254.02213744339 31.1994528531185 8.14187795661935 1.4620038670397e-14 -161.577447809525 111.050786344929 -1.45498697602786 0.146838782656326 KIF16B other 1.31174391263836e-11 1 2.1250226207422e-10 8.14187795661935 -1.45498697602786 8.38274661929078e-19 215.576445604773 25.1660150526136 8.56617327590707 8.0909007668457e-16 -250.961333985266 91.9668290259143 -2.72882447555684 0.00677032003626606 TRMT6 other 1.203259449733e-14 1 1.19510695227078e-11 8.56617327590707 -2.72882447555684 0.662312534778375 -26.7663735974264 125.729300087489 -0.212888909576375 0.831573078027896 -417.400924855073 459.465871752832 -0.90844815799423 0.364445686158604 CHGB other 1 1 1 -0.212888909576375 -0.90844815799423 0.0036990477434913 389.831785952743 236.084054732035 1.651241488525 0.0998518529219473 -1131.37154621475 490.518758929961 -2.30647967201658 0.021841250193482 PEBP1 other 1 1 1 1.651241488525 -2.30647967201658 0.835645776387297 -10.016167633706 18.4048551521031 -0.544213336694557 0.58674215154686 -15.2718273330929 39.1496647168353 -0.390088330093046 0.69677765337827 TBX5 other 1 1 1 -0.544213336694557 -0.390088330093046 2.89045560802905e-11 106.252803245303 21.1747746890582 5.01789534035551 9.50824821907925e-07 -158.719492130739 44.07830153435 -3.60085317731787 0.00037759617108519 BRAP other 3.36651364667143e-07 1 0.0105617621217532 5.01789534035551 -3.60085317731787 3.41965187666265e-07 763.37390133972 173.76683219199 4.39309327165663 1.60677151281954e-05 -749.039367171684 364.650914157051 -2.05412721617114 0.0409260983218777 ERP29 other 0.00316557174222662 1 0.162251787364517 4.39309327165663 -2.05412721617114 0.340720988896939 63.784275279359 44.1852747485525 1.44356407518884 0.150012372282844 16.3854446361482 92.6166276942232 0.17691687814682 0.85970534387369 NOS1 other 1 1 1 1.44356407518884 0.17691687814682 5.70492991630128e-07 1512.76495679555 308.74453754388 4.89973027160212 1.66946070613635e-06 153.013553261077 637.155055358594 0.240151203343996 0.810398009077202 FUS other 0.00518292882895971 1 0.0182221636074782 4.89973027160212 0.240151203343996 0.0100050514453067 309.827919424661 101.380903410533 3.0560777128809 0.00246549355179705 222.905339123111 418.421717648333 0.532728894608799 0.594656204979161 FXYD5 other 1 1 1 3.0560777128809 0.532728894608799 4.41541158099837e-16 143.098555894775 16.5710653790237 8.63544694452263 5.25114778912535e-16 -31.8730764267367 64.3118781970113 -0.495601704075529 0.620580083013054 ZNF302 other 5.99966125626058e-12 1 7.78062567914703e-12 8.63544694452263 -0.495601704075529 8.38516078956341e-07 211.768026254102 45.1803816046868 4.6871677204279 4.38482635953306e-06 -313.825550867323 188.485357489371 -1.66498636842398 0.0970668628134142 GRAMD1A other 0.00750639593881717 1 0.0463476146202644 4.6871677204279 -1.66498636842398 1.39272701139969e-07 147.989078064288 41.6768615003077 3.55086906107831 0.000452325471681966 -172.721711569956 81.3307223843958 -2.12369577579326 0.0345981764955408 CDIP1 other 0.00132141938841603 1 1 3.55086906107831 -2.12369577579326 0.000137139753989875 2.05368956889552 1.71064196609526 1.20053734773227 0.23097138413989 -8.24370728303873 2.98880064810112 -2.75819910848728 0.00620462902860814 CMTM1 other 0.998925968062253 1 1 1.20053734773227 -2.75819910848728 6.17236026451029e-08 2788.38282981823 585.443526467892 4.76285534599922 3.12424084634139e-06 -2209.60156438026 1195.66243896777 -1.84801453350648 0.0656978604996883 GANAB other 0.000598657222054853 1 0.0333950104065431 4.76285534599922 -1.84801453350648 0.000509673003271848 68.6540992575395 24.5290139903362 2.79889355864803 0.0054988832600961 -72.182850763724 56.5349134065397 -1.27678360882347 0.202779718154195 GMIP other 1 1 1 2.79889355864803 -1.27678360882347 5.23692297389453e-12 745.357026829926 102.067343011095 7.30260046789796 3.10068675245691e-12 19.643238508845 223.254570629595 0.0879858291521181 0.929952444754316 BIRC5 other 6.27121526123869e-08 1 4.32111705822395e-08 7.30260046789796 0.0879858291521181 0.0666563441087206 28.8866565243885 13.5642939318289 2.12961003864753 0.0341017481106827 87.1357167686759 64.1471247553789 1.35837291384396 0.175470925545744 LAG3 other 1 1 1 2.12961003864753 1.35837291384396 7.02514866155033e-25 1835.88494941292 161.577978650457 11.3622225302403 9.68580078519031e-25 -494.463112037458 764.121067141705 -0.647100483549109 0.518112633266606 MLF2 other 1.07505849967705e-20 1 1.51243779260747e-20 11.3622225302403 -0.647100483549109 1.6620438825398e-08 38.0625995615351 9.38688842766189 4.05486864522324 6.54933841717601e-05 -45.3944273141649 19.105454182794 -2.37599310018216 0.0181920651312853 OTUB2 other 0.000167002169317599 1 0.626116752682026 4.05486864522324 -2.37599310018216 3.68291769083692e-20 697.906171632259 84.7110052513414 8.23867181792424 7.32157556150526e-15 -318.667876520038 172.415198292822 -1.84825862032665 0.06564634466771 DDX24 essential 5.39326466646158e-16 1 1.06865716895731e-10 8.23867181792424 -1.84825862032665 1.30088543216075e-21 106.286913253321 15.007874377496 7.08207642067525 1.20577055545232e-11 -98.0665154438542 27.833580966977 -3.52331651325083 0.000499463994041367 ZBTB25 other 1.93831929391951e-17 1 1.65528181852494e-07 7.08207642067525 -3.52331651325083 1.92104652210678e-13 216.30673155214 27.172495114371 7.96050309850786 4.72365567697475e-14 0.513621078010392 127.276575721477 0.00403547216052042 0.996783136787484 NECAP1 other 2.42743438533412e-09 1 6.80914965835911e-10 7.96050309850786 0.00403547216052042 0.673944406436071 -2.41247850789987 4.58508584647334 -0.526157762074499 0.599205769609956 -7.13221287458359 8.02328843366256 -0.88893886011372 0.374818533267023 ANKRD24 other 1 1 1 -0.526157762074499 -0.88893886011372 3.3930236088796e-17 279.258029075734 47.5367518506383 5.8745711098051 1.2302972163613e-08 -167.419311704019 65.6501442409965 -2.55017431628841 0.0113134931034129 DHX32 other 4.73632165563504e-13 1 0.000152126250803075 5.8745711098051 -2.55017431628841 1.47647185009933e-20 389.798082653777 50.4213640632282 7.73081192656691 2.16114197478612e-13 -306.645584523992 111.807132008816 -2.74262991112063 0.00650574228029485 RCOR1 essential 2.17321891616121e-16 1 3.08719131098197e-09 7.73081192656691 -2.74262991112063 2.07750126696803e-13 211.493548102643 28.6922585242333 7.37110143922678 2.03892794581606e-12 25.3191705123305 53.7199600584721 0.471317746416258 0.637791649166944 GPATCH2L other 2.62242984929374e-09 1 2.85184851781293e-08 7.37110143922678 0.471317746416258 0.0109084844383466 383.909621751694 186.914861217857 2.05392775753787 0.040938454636758 -1243.87573968499 780.826250745256 -1.59302500203827 0.112315963695708 LTBP4 other 1 1 1 2.05392775753787 -1.59302500203827 3.0887991594145e-09 412.52093495482 67.5404649058021 6.10775977823306 3.52359840113654e-09 -178.1276756471 287.587427184459 -0.619386172027782 0.536186221328603 BLVRB other 3.24447463704899e-05 1 4.46158029551909e-05 6.10775977823306 -0.619386172027782 3.27052973243885e-06 277.652026259461 114.946670048373 2.41548559991009 0.016378633848644 -391.006289834623 167.353697824506 -2.33640663407777 0.0202018837475909 SLC9A1 other 0.0278845364987736 1 1 2.41548559991009 -2.33640663407777 4.64277533855964e-23 236.707751576713 37.7040552483218 6.27804489511108 1.35580025623872e-09 -420.164268333212 73.9787359988264 -5.67952753801953 3.47648548394687e-08 SPTLC1 essential 7.01384070396204e-19 0.000551022949205579 1.74423702965111e-05 6.27804489511108 -5.67952753801953 1.65247144812384e-23 1070.08773252397 117.817857132093 9.08255979672273 2.31714619826793e-17 -619.127514729452 266.999360164674 -2.31883520000797 0.0211508231146661 PAPOLA other 2.50564245679018e-19 1 3.48104873365791e-13 9.08255979672273 -2.31883520000797 1.13819724843153e-22 490.168409399851 53.5147580583547 9.15949968166446 1.37006217319847e-17 -187.906748203812 117.553770473204 -1.59847487194505 0.111111236174033 CCNK essential 1.71344213778882e-18 1 2.06276560796762e-13 9.15949968166446 -1.59847487194505 0.0238665700563289 48.3454083161025 41.9190635253152 1.15330363444084 0.249801961289049 -195.517495086471 99.0822717362671 -1.97328433896723 0.049479107470598 PCBP4 other 1 1 1 1.15330363444084 -1.97328433896723 0.900005364557102 -32.5324605281245 124.675545434402 -0.260936981785586 0.79434453577881 123.919029339086 346.108604183983 0.358035101817964 0.720603145725079 RGS1 other 1 1 1 -0.260936981785586 0.358035101817964 7.87369416837891e-05 122.022754289244 56.6001695603417 2.15587259255744 0.0319870901250688 -263.387090198672 113.218783344688 -2.32635506598588 0.0207484041154537 YPEL3 other 0.590842010395153 1 1 2.15587259255744 -2.32635506598588 5.19623172372187e-14 262.40609170958 35.7710128093213 7.33571881535325 2.52277485680396e-12 -81.3410666057379 98.7389201537639 -0.82379943470181 0.410772627735352 MRPS33 other 6.68235399670633e-10 1 3.52280281004105e-08 7.33571881535325 -0.82379943470181 3.54935003366521e-16 370.28265637907 51.0841093196823 7.24849001598239 4.33769463277242e-12 -319.461825755312 141.00774328447 -2.26556228980155 0.0242616969348414 NDUFB2 other 4.83527955086212e-12 1 6.02115391975139e-08 7.24849001598239 -2.26556228980155 3.25712153319737e-18 615.090147717825 106.19609867222 5.79202207433562 1.9235697735558e-08 -457.54741926915 153.074563668677 -2.98904931233049 0.00305531347995742 NUDC essential 4.63292966881994e-14 1 0.000235425704585495 5.79202207433562 -2.98904931233049 7.00212305918777e-83 866.360564273345 32.9854360612087 26.2649419782022 1.87958301474586e-76 55.6725397879097 89.6287908479085 0.621145719597854 0.535025847156722 MAEA other 1.11823905255229e-78 1 3.00037836643882e-72 26.2649419782022 0.621145719597854 0.335124541054469 901.511491311591 1011.40015922573 0.891349959843529 0.373526364526006 3139.5417618821 2147.14179932791 1.46219581904876 0.144837740400741 ICAM1 other 1 1 1 0.891349959843529 1.46219581904876 3.44526638480551e-21 495.166152635792 75.4935691379939 6.55905076802877 2.73273994642876e-10 -822.80151112322 173.933331478775 -4.73055684110567 3.60768910578487e-06 STRN4 other 5.11277531505138e-17 0.0559805118544639 3.59956505743596e-06 6.55905076802877 -4.73055684110567 0.560898476245481 -782.514407034513 935.440278944148 -0.836519898328255 0.403602225448237 1917.41898596126 3954.13206858383 0.484915261479364 0.628129637068871 LYZ other 1 1 1 -0.836519898328255 0.484915261479364 1.45202475598831e-12 126.179800347837 34.6304777359146 3.64360553469864 0.000321715227951324 -170.547665803251 50.7837788435642 -3.35830987151647 0.000895838814404619 MUL1 other 1.77887552856128e-08 1 1 3.64360553469864 -3.35830987151647 9.99688591713125e-11 167.444532488114 26.0757547390214 6.42146446628212 5.99290049500353e-10 34.1456418383516 50.4065315284759 0.6774051061034 0.498724715376107 TFAP4 other 1.13764561736954e-06 1 7.8039550245936e-06 6.42146446628212 0.6774051061034 5.17586207391406e-17 171.70552341129 21.38125190092 8.03065808339789 2.97985740586642e-14 -46.9555598774735 42.1897970226474 -1.11296008018877 0.26671181232758 PDCD7 essential 7.1908251792888e-13 1 4.31095970906695e-10 8.03065808339789 -1.11296008018877 7.19672428918201e-13 467.349044759636 76.8265835503801 6.08316839252867 3.99959531566586e-09 -331.577919552125 151.595331318955 -2.18725680182386 0.0295784654056271 SPG21 other 8.91890041158327e-09 1 5.05268876228068e-05 6.08316839252867 -2.18725680182386 3.12436810576916e-08 71.7113257693564 12.4418212474567 5.76373220150669 2.26521452874531e-08 290.627814167184 114.408099429954 2.54027307170783 0.0116436637677654 FETUB other 0.000309093736703743 1 0.000276288216071066 5.76373220150669 2.54027307170783 7.07911500867055e-27 640.135219080199 53.0610780326502 12.064120119955 5.0573630712277e-27 -615.203730252157 487.990628158064 -1.2606875926578 0.208526110715836 DNAJB11 other 1.09513909184133e-22 1 7.93854281290613e-23 12.064120119955 -1.2606875926578 0.298267533613505 185.196393216958 120.547132492847 1.53629861936323 0.125671890262996 -131.398600143072 996.725002989895 -0.131830344125926 0.895219664350996 P3H2 other 1 1 1 1.53629861936323 -0.131830344125926 0.0406934187400493 1.5052498210937 1.97895697563455 0.760627865904484 0.447545565656191 52.7199920354156 21.5180147435965 2.45003977660645 0.0149216426864118 THPO other 1 1 1 0.760627865904484 2.45003977660645 0.0517346543714153 17.0614044795612 7.00614864878017 2.43520446608447 0.0155335134636976 -13.1620443559761 76.1807415605588 -0.172773906979012 0.862959072321006 CHRD other 1 1 1 2.43520446608447 -0.172773906979012 0.0028745650251705 2.49932475538723 7.9685241288123 0.313649643897076 0.75402754710796 -50.0427041796107 16.5451516373517 -3.0246144173521 0.0027275149728288 FLT3LG other 1 1 1 0.313649643897076 -3.0246144173521 7.9325216579144e-09 365.637917665783 76.4321289705949 4.78382484683178 2.86385070991246e-06 -106.378208354614 139.391030641603 -0.763163941503021 0.446047044124966 RAB11FIP3 other 8.13321445585963e-05 1 0.0307233904159409 4.78382484683178 -0.763163941503021 2.78434321195384e-12 65.2127009337994 44.1301552513948 1.47773558833646 0.140635525996277 -436.605856174423 80.6934251297998 -5.41067448149733 1.37766470620565e-07 GNPTG other 3.37267493263969e-08 0.00217505703815748 1 1.47773558833646 -5.41067448149733 0.00599032942205462 57.2264539372107 24.3313623474024 2.3519625872211 0.0193985710608566 -83.4940800743903 50.2404329987043 -1.66189013690514 0.0977040068476877 ZNF268 other 1 1 1 2.3519625872211 -1.66189013690514 0.000283048733003632 172.895356973469 71.2697383612878 2.42592944703978 0.0159247842310274 -393.936363521603 146.686102701017 -2.68557386328917 0.00768897854974877 GOLGA3 other 1 1 1 2.42592944703978 -2.68557386328917 1.38166669643775e-20 1028.25330656411 105.178083650788 9.77630767620861 1.60273337809384e-19 -130.443807854729 287.433403462166 -0.453822716091867 0.650320994142002 PABPC4 other 2.03450421050458e-16 1 2.44721359501148e-15 9.77630767620861 -0.453822716091867 0.391997395481809 -22.5319267520855 21.2009053297586 -1.06278134832565 0.288823769631165 12.131879598674 47.2709180431243 0.256645736975245 0.797646279020799 CD209 other 1 1 1 -1.06278134832565 0.256645736975245 8.90526624289423e-08 310.535147947199 60.0792716534233 5.16875686740295 4.55879321194777e-07 -1.82777715628133 138.104970277837 -0.0132346949758886 0.989450215979949 CERS4 other 0.000855350822629991 1 0.00517012738166997 5.16875686740295 -0.0132346949758886 3.89072013277535e-19 175.819897249522 21.6524268363348 8.12010120521362 1.63184310082364e-14 -59.7783937924613 48.0795312291908 -1.24332314114094 0.214819368400712 MCOLN1 other 5.61781079971432e-15 1 2.37041528825643e-10 8.12010120521362 -1.24332314114094 1.06679548819292e-18 355.856595126275 60.0284312862018 5.92813417744722 9.29449838057758e-09 -240.628101047511 89.1746767859863 -2.69839050412263 0.00740503664003034 USP48 other 1.52893129367809e-14 1 0.000115586381860863 5.92813417744722 -2.69839050412263 6.69126246166602e-09 378.876967625292 104.752922989394 3.61686296489934 0.000355125719738543 -476.66838694552 189.312676134083 -2.51788943392208 0.0123785346868768 PDPR other 6.89066208302366e-05 1 1 3.61686296489934 -2.51788943392208 2.8648872149175e-14 1201.2039394586 218.612877244004 5.49466232091115 8.97374544912211e-08 -968.047502539842 395.083856825879 -2.45023299690647 0.014904404377124 AARS essential 3.71375329669755e-10 1 0.00106356831062995 5.49466232091115 -2.45023299690647 7.27861951149268e-14 1512.20505292905 282.597060839273 5.35109971928941 1.86277927073212e-07 -1008.67284516354 480.301448080962 -2.10008287335731 0.0366459282781004 GLG1 other 9.31881656056407e-10 1 0.00216771623735097 5.35109971928941 -2.10008287335731 7.5196405354104e-14 321.138873920225 51.4832146905359 6.23773934573785 1.7147005840503e-09 -210.648546300904 110.217503311334 -1.91120774806411 0.0570405952499758 TNRC6A other 9.62513988532532e-10 1 2.19653144816843e-05 6.23773934573785 -1.91120774806411 4.6012324166021e-21 314.401574363923 29.9407263278507 10.5007998443735 7.46491894134687e-22 92.9169657602046 225.91018686483 0.411300468782314 0.681178502618742 PLEKHG2 other 6.81810619492099e-17 1 1.1528074321122e-17 10.5007998443735 0.411300468782314 4.50439111757939e-30 161.660244000366 12.2144287450148 13.2351866284656 3.51289470608735e-31 181.866476157917 92.3233886331888 1.96988519215313 0.0498697060006347 DLL3 other 7.05838088124691e-26 1 5.54931976720619e-27 13.2351866284656 1.96988519215313 0.000234639093743286 64.8540100118354 21.713989174768 2.98673861766482 0.0030797104848843 -66.7075730667382 47.9996219156106 -1.3897520522978 0.16575325367153 NAT14 other 1 1 1 2.98673861766482 -1.3897520522978 0.00539911088001524 66.167725808055 35.2221267728995 1.87858405696744 0.0613707789283046 -147.561864606089 73.0549564340864 -2.01987478754062 0.0443767173501836 PITPNM2 other 1 1 1 1.87858405696744 -2.01987478754062 6.53904699632226e-36 355.3225340942 28.658372456965 12.3985594306785 6.38963118137316e-28 -151.625495287365 63.3992160040055 -2.39159890049406 0.0175032923670148 EXOC1 essential 1.03415028246837e-31 1 1.00432222908823e-23 12.3985594306785 -2.39159890049406 6.43950882533531e-11 193.621136138801 30.9120670329735 6.26361012779469 1.4633965201313e-09 -5.39867970474138 51.6397869391347 -0.104544964740163 0.916813934778988 RBM27 other 7.39062427883733e-07 1 1.87973283010866e-05 6.26361012779469 -0.104544964740163 0.0122194085200022 135.455538876245 72.1266444994885 1.87802357667152 0.0614596545585746 -283.72235404258 170.99921911391 -1.65920262977096 0.0982403598138857 OSBPL8 other 1 1 1 1.87802357667152 -1.65920262977096 0.0214333271359373 27.221784080487 56.7319607819196 0.479831539493741 0.631735650711476 -468.074125650654 189.896047847373 -2.46489661557813 0.0143280462029551 DTX2 other 1 1 1 0.479831539493741 -2.46489661557813 0.741427663708744 -5.04414511333244 8.8342586236976 -0.570975486250957 0.568491181117844 -18.8718006185844 34.731494163893 -0.543362762613409 0.587328377028531 NLRC4 other 1 1 1 -0.570975486250957 -0.543362762613409 2.04528442886105e-18 251.711024876236 27.7679838859354 9.06479296121059 2.714928563162e-17 -120.901679582117 105.151270491947 -1.14978810067137 0.251256153631063 PUS7 other 2.91984805064204e-14 1 4.07565075901879e-13 9.06479296121059 -1.14978810067137 0.370343111744796 -3.65582718259066 5.80838515911794 -0.629405089786751 0.529618060522611 -26.5448159616457 19.149166219306 -1.38621262448929 0.166829912034135 LAMB4 other 1 1 1 -0.629405089786751 -1.38621262448929 0.0335761239390052 311.868105387845 142.416659260859 2.18982882344268 0.0293988016607499 -386.167798105083 469.287057352907 -0.822881841837548 0.411306772228583 NRCAM other 1 1 1 2.18982882344268 -0.822881841837548 0.0177847851115789 531.762702870839 249.770031544317 2.12900923134362 0.0341585721426905 -1135.80635268366 878.72324472115 -1.2925643648406 0.197266815832102 LAMB1 other 1 1 1 2.12900923134362 -1.2925643648406 0.0613468647096717 29.4033090249995 25.1087014843429 1.17104060691209 0.242611094978635 203.569577044831 88.5198261482092 2.2997060195757 0.0222252377205707 SLC26A4 other 1 1 1 1.17104060691209 2.2997060195757 1.76992033025495e-18 446.931732933232 51.539188526885 8.6716874228645 4.03733023642881e-16 -380.936869810673 181.321524814733 -2.10089160787667 0.0365776635351776 DLD other 2.53010111209945e-14 1 5.99139807086035e-12 8.6716874228645 -2.10089160787667 0.0560220261097 70.3350485947352 112.401664599666 0.625747393023434 0.532011183304147 -311.482873414229 189.223994115533 -1.64610664133878 0.100909614041783 WDR7 other 1 1 1 0.625747393023434 -1.64610664133878 3.26476545030701e-24 555.987863614405 76.8096386786811 7.23851684734877 4.79467378502137e-12 -495.142269504108 129.306526304796 -3.82921329382075 0.000160118657431869 TXNL1 other 4.97582902281291e-20 1 6.64685626817513e-08 7.23851684734877 -3.82921329382075 0.0221604322589631 -3.49746237311871 8.26419213834609 -0.423206807703609 0.67249288626497 -63.4604400674582 23.2238060590607 -2.73255985285406 0.00671369641782203 IL5RA other 1 1 1 -0.423206807703609 -2.73255985285406 8.29140174417011e-25 1666.31717410582 152.012667813137 10.9616994299065 2.33313726631311e-23 -496.473271779885 499.297773032673 -0.994343052572352 0.320949470471556 CMTM6 other 1.26783824070105e-20 1 3.62826176284351e-19 10.9616994299065 -0.994343052572352 6.25199571639327e-05 2225.07135697711 591.114257560466 3.76419842444674 0.000205023400473432 -1883.67029836196 1772.01765179941 -1.06300876656007 0.288727790576962 ITGA6 other 0.474588994831413 1 1 3.76419842444674 -1.06300876656007 0.654842712309753 8.55741158312033 13.2417733527648 0.646243622749636 0.51867050071635 -16.7014351324651 40.0418226774326 -0.41709977258048 0.676936870186444 RAPGEF4 other 1 1 1 0.646243622749636 -0.41709977258048 4.32295235235628e-06 412.145361900237 81.5826491228662 5.05187520056541 8.0683186506757e-07 257.636523103145 246.697922000828 1.0443400617792 0.297262186285279 MAP3K20 other 0.03654623918682 1 0.00900227808541059 5.05187520056541 1.0443400617792 1.92337015853126e-11 376.871478391974 51.2934008180655 7.34736773895562 2.40323499040015e-12 50.1845447398938 137.505556287761 0.364963759245272 0.715424167822176 FH ts 2.25745955506814e-07 1 3.35659831109189e-08 7.34736773895562 0.364963759245272 0.0141765837270147 -1.57482925241525 263.311156858122 -0.00598086792525773 0.995232452454502 -841.968886570327 379.301235712511 -2.2197894636138 0.0272732684688248 SEL1L3 other 1 1 1 -0.00598086792525773 -2.2197894636138 0.711693850842268 -16.5842736700802 22.3094878956015 -0.743373122130245 0.457895064456512 -53.1239140451908 111.876630044782 -0.474843709753559 0.635278013924643 TF other 1 1 1 -0.743373122130245 -0.474843709753559 5.40100982803254e-15 740.911413019468 90.3750442586302 8.19818589409671 9.59629172996892e-15 -583.44319159725 453.208762079967 -1.28736079355479 0.199058896543628 CDV3 other 7.14067509364181e-11 1 1.39865951964297e-10 8.19818589409671 -1.28736079355479 0.0311125430934909 7.72904436897094 5.53603576929448 1.39613338696978 0.163812725854825 -17.9278833320675 13.7325345032548 -1.30550433554843 0.192824333598952 MYO15A other 1 1 1 1.39613338696978 -1.30550433554843 2.91503788640039e-22 876.501079655805 94.0738757607892 9.31715710198408 4.24093781984999e-18 -127.972142709887 233.357008259464 -0.548396397710061 0.583869562277094 ALKBH5 other 4.37459735612106e-18 1 6.41314617117716e-14 9.31715710198408 -0.548396397710061 0.94808844833465 2.22765020529417 6.82817053994282 0.326244078448695 0.744493361380431 0.912968925779372 14.9651930338085 0.0610061576697904 0.951399605616051 APOH other 1 1 1 0.326244078448695 0.0610061576697904 0.0416224779731726 11.1500737463122 96.6553540168446 0.115359090654916 0.908245307921422 -689.487687572147 286.481881194117 -2.4067409942235 0.0167599576118779 NLRP1 other 1 1 1 0.115359090654916 -2.4067409942235 2.32012788585258e-05 180.810940455814 39.433995842973 4.58515391581942 6.91505282273114e-06 22.4404421066648 118.135840113526 0.189954564889877 0.849485897332862 PITPNM3 other 0.183939738790393 1 0.0719580396733402 4.58515391581942 0.189954564889877 1.01383997478551e-20 294.959531628863 29.3691198113682 10.0431859559744 2.20922239456549e-20 -10.8595960836076 93.0540576333412 -0.116702015578916 0.907182630743765 SPAG7 other 1.49561673080358e-16 1 3.38695885310835e-16 10.0431859559744 -0.116702015578916 3.8205071555794e-09 145.726570191505 28.5818449247982 5.0985711585423 6.59746744473812e-07 -18.6757221253857 50.5896276533769 -0.369161090754521 0.712308112035485 ORC6 essential 3.98792130390188e-05 1 0.00740565720671854 5.0985711585423 -0.369161090754521 0.0066722528777898 113.411059667863 37.9745570869985 2.98650118309588 0.00308301833257586 4.1191126033944 118.361946274129 0.0348009874208594 0.97226433898957 ZFHX4 other 1 1 1 2.98650118309588 0.0348009874208594 1.20971775504514e-22 95.8324782766988 10.4549919277641 9.16619342595643 1.26250604509762e-17 -65.6633342618541 27.9742045895712 -2.34728154831374 0.0196308021858113 ZC3HC1 other 1.82074619311843e-18 1 1.90133410391701e-13 9.16619342595643 -2.34728154831374 0.0662849199348861 18.5253227312854 16.4380488628171 1.12697820075165 0.260744924316215 -49.0259352490374 31.2134165031046 -1.5706686656413 0.117422145256172 ESR1 other 1 1 1 1.12697820075165 -1.5706686656413 0.365757825357746 -0.0833247094340665 16.9681859733456 -0.00491064333953887 0.996085488842956 -43.4935463495926 32.2640580378601 -1.34804947035972 0.178764039929775 RGS17 other 1 1 1 -0.00491064333953887 -1.34804947035972 0.311413045861275 74.3355814097253 89.5483972472934 0.830116268909236 0.407201034480938 -76.9130494282678 150.046663051344 -0.512594201458175 0.608651213200852 ANGPT2 other 1 1 1 0.830116268909236 -0.512594201458175 3.09081219145231e-09 142.684928354454 27.2347444301365 5.23907719128683 3.24626201672656e-07 -75.9385012707573 56.4817846627456 -1.34447772364468 0.179918232872845 TMEM101 other 3.24628004468236e-05 1 0.00372119014977366 5.23907719128683 -1.34447772364468 0.00197934544081577 175.543506022413 49.2641807841335 3.5633091473014 0.000432585280577774 102.987434104309 183.025671947298 0.562693927079062 0.574108506477034 CD200 other 1 1 1 3.5633091473014 0.562693927079062 0.325273300646336 -235.983067074603 283.193419379323 -0.833292904869781 0.405413373241274 -1472.26089490288 1052.11667073224 -1.39933235149504 0.162856903891271 CCDC80 other 1 1 1 -0.833292904869781 -1.39933235149504 3.61114097279342e-07 586.233095588969 181.758956714224 3.2253326393741 0.00141198041461474 -787.073040606202 361.760874707618 -2.17567209622193 0.0304407708678939 PSME1 other 0.00333597203066656 1 1 3.2253326393741 -2.17567209622193 3.85374322104403e-06 41.9270369304639 20.1848670951239 2.07715199376232 0.0387508431672514 -107.121946470335 37.8364159944204 -2.83118640217223 0.00499311179229806 PPP2R3C essential 0.0326874500008955 1 1 2.07715199376232 -2.83118640217223 0.25338087315189 0.225286550308573 13.3735218345594 0.0168457159673822 0.986572003626975 -38.0915472111011 27.162605773527 -1.40235246679557 0.161946102573871 JPH4 other 1 1 1 0.0168457159673822 -1.40235246679557 3.70229221464205e-07 2345.71745210586 542.494265180465 4.32394884640031 2.15041677802889e-05 -778.610923405644 1104.57043887543 -0.704899294786809 0.481473850050391 SLC7A8 other 0.00341610502645022 1 0.214762123621745 4.32394884640031 -0.704899294786809 1.82731508293803e-16 143.499915690495 22.2080452594946 6.4616184816691 4.76366051037095e-10 -117.20577139891 47.3556531818264 -2.47501118713086 0.0139329718835774 OSGEP essential 2.50506624719974e-12 1 6.22372245679965e-06 6.4616184816691 -2.47501118713086 0.0214410196569172 53.8270885124316 31.76518424095 1.69453097152324 0.0913089843063912 -64.3258437640815 64.4215259245186 -0.998514748617578 0.318917276222338 SLC22A17 other 1 1 1 1.69453097152324 -0.998514748617578 2.16585443673513e-25 243.444091654616 34.1167232749525 7.13562347980075 8.75513178907448e-12 -290.271083156252 67.9036448999311 -4.27474966305597 2.65022486906419e-05 RNF31 other 3.3248031458321e-21 0.403417229568951 1.20671981448814e-07 7.13562347980075 -4.27474966305597 7.3590020662391e-25 273.040484567831 35.3441409795003 7.72519792534202 2.28510228831498e-13 -226.493743899394 63.8300762368159 -3.54838592169434 0.000458055684891315 SCFD1 essential 1.12592731613458e-20 1 3.26266904725613e-09 7.72519792534202 -3.54838592169434 1.12146714353837e-18 150.353316081387 23.8969899536444 6.29172612839707 1.28572350424326e-09 -138.297786756861 43.1569886351532 -3.20452819185377 0.00151780161474034 G2E3 other 1.60650168311872e-14 1 1.6558833011149e-05 6.29172612839707 -3.20452819185377 8.88380370408885e-13 477.871111503329 115.404613121434 4.14083197003999 4.6505991305264e-05 -738.008780832194 208.263632845989 -3.54362771237142 0.000466018683471945 HECTD1 essential 1.09706091941793e-08 1 0.450224501826261 4.14083197003999 -3.54362771237142 4.76460193683875e-07 1006.35010200193 237.994335342682 4.22846241509453 3.21692633744298e-05 -436.696847991881 504.621522033221 -0.865394813586908 0.38758475090898 HNRNPC essential 0.00435913431201377 1 0.316384705287517 4.22846241509453 -0.865394813586908 0.00243689475268269 2.93147455611159 1.06640483963882 2.74893215704501 0.00638081825543118 -0.957111323039323 2.2618450504933 -0.423155124101264 0.67251769268582 RPGRIP1 other 1 1 1 2.74893215704501 -0.423155124101264 1.2312033733181e-29 1097.242515028 115.453049845822 9.50379844008688 1.13258874274868e-18 -684.333797848911 244.774584468372 -2.79577146187469 0.00554794177326674 SUPT16H essential 1.9263407978935e-25 1 1.72028904136097e-14 9.50379844008688 -2.79577146187469 1.3521741781668e-40 615.029939937975 50.4981860237201 12.1792481743618 1.65306959671364e-27 -307.592186973678 107.920994554874 -2.85016078884704 0.00470539287699133 TOX4 other 2.14603563816854e-36 1 2.59664172251778e-23 12.1792481743618 -2.85016078884704 2.50195266606025e-19 110.257192471393 14.1078910634432 7.81528521701547 1.36347809252517e-13 -30.1296895076564 26.3555693688345 -1.14320009884836 0.254007049893859 GEMIN2 other 3.62282746045524e-15 1 1.95168254164052e-09 7.81528521701547 -1.14320009884836 0.00506750436747335 131.091740701702 109.547955576729 1.19666076844203 0.232480788294321 -418.674278472117 214.684933483004 -1.95018006936785 0.0521818047346201 TGM1 other 1 1 1 1.19666076844203 -1.95018006936785 1.20202224494752e-14 269.360384354765 48.6796763241406 5.53332324071324 7.38534457984408e-08 -240.098937785475 95.3992524881254 -2.51678007451223 0.0124187951521069 TINF2 other 1.57344711863631e-10 1 0.00087915141878464 5.53332324071324 -2.51678007451223 0.168336223307 188.550234278666 114.047461261423 1.65326112649246 0.0994313964526815 300.778138773677 187.845986147236 1.60119545241666 0.110494367255567 SEMA6A other 1 1 1 1.65326112649246 1.60119545241666 2.67336326524855e-11 342.457977456546 59.5938444308036 5.74653272879861 2.44617410131133e-08 -183.151493687588 113.714109680106 -1.61063120665341 0.108424230475318 TRPM7 essential 3.11660689462676e-07 1 0.000297992929021746 5.74653272879861 -1.61063120665341 9.13724099214675e-10 156.955540517976 34.9740423838601 4.48777235400185 1.06347568983156e-05 -119.752279218554 61.3576473788911 -1.95170910773467 0.0519989236898486 TYRO3 other 9.89289082219729e-06 1 0.109006258207735 4.48777235400185 -1.95170910773467 0.00073801524231418 112.059883475635 31.3607639501573 3.57325107429577 0.000417196939417156 27.4043264557366 56.339520820806 0.486413907262347 0.627066850275229 WDR76 other 1 1 1 3.57325107429577 0.486413907262347 0.140013230796791 -17.0765776841746 18.0592280527165 -0.945587354804233 0.345195254432933 -62.7120488067368 31.5226835739564 -1.98942607978175 0.0476519222462687 CAPN3 other 1 1 1 -0.945587354804233 -1.98942607978175 5.16540232229203e-08 141.459919999386 56.2008121217597 2.51704405432632 0.0124097108381041 -340.444856784092 98.1517856888627 -3.46855489581503 0.000608152868290577 SNAP23 essential 0.000503626726423473 1 1 2.51704405432632 -3.46855489581503 0.00284219509627525 16.9286065495992 10.7195079744016 1.57923354225074 0.115522124777206 -30.7131351411969 18.9562165227175 -1.62021440852343 0.106422173710798 TBX15 other 1 1 1 1.57923354225074 -1.62021440852343 8.04181022753583e-19 2628.96895339609 282.976373926012 9.29041854951278 7.81160139862701e-18 1166.5978163309 502.26971314157 2.32265212456098 0.0210012803591069 PHGDH other 1.15472353057187e-14 1 1.1783019549689e-13 9.29041854951278 2.32265212456098 0.000974927791113107 325.210358801336 86.9696000061006 3.73935672670133 0.000225106782407476 126.391848507955 244.336335408864 0.517286339325891 0.605378238591182 COL9A3 other 1 1 1 3.73935672670133 0.517286339325891 2.68907794949768e-07 1635.95841207298 436.259611809327 3.74996531374533 0.000215937642775384 -2457.86086318571 863.969183949577 -2.8448478358334 0.00477970977998245 EZR other 0.00250406938657224 1 1 3.74996531374533 -2.8448478358334 0.659498986054168 385.172327603126 872.56309276058 0.441426334437929 0.659255081871213 -1410.09975524435 2322.83390983141 -0.607060086937812 0.544317439488523 MYL6 other 1 1 1 0.441426334437929 -0.607060086937812 1.0408063574479e-10 412.78727223003 97.6116854931855 4.22887147316853 3.2150039645712e-05 -368.494931078533 139.753535861999 -2.63674853595409 0.00885356316871998 AGO1 other 1.1827723446038e-06 1 0.316227789955223 4.22887147316853 -2.63674853595409 0.0138478590540485 35.2948567806837 12.8673051681551 2.74298746469726 0.00649424724579887 9.07281531421526 18.3841537343937 0.493512807023666 0.622049997924336 TEKT2 other 1 1 1 2.74298746469726 0.493512807023666 8.22651471274539e-08 142.375037441234 30.0069942392319 4.74472838919298 3.38218078947824e-06 -21.4828681938349 42.9619007635724 -0.500044639832377 0.617449434134556 CLSPN other 0.000792048836543126 1 0.036060811577417 4.74472838919298 -0.500044639832377 1.23790162548998e-15 332.197372991543 59.3601394268169 5.59630378565901 5.35686402505957e-08 -385.094288218006 115.943492232857 -3.3213963181702 0.00101874362971978 RFFL other 1.66361599449598e-11 1 0.000642770114366898 5.59630378565901 -3.3213963181702 0.145993845337275 -57.3559685750433 78.6071567965449 -0.729653264568454 0.466232351280237 296.195387743234 183.546407739271 1.61373568347892 0.107748537099884 UNC13D other 1 1 1 -0.729653264568454 1.61373568347892 9.39274262038757e-10 268.598515955562 45.5458969686584 5.89731531998136 1.09296920785994e-08 -147.05059716114 100.524912761506 -1.46282740388958 0.144669133910402 MFSD11 other 1.01601296924732e-05 1 0.00013547353331424 5.89731531998136 -1.46282740388958 0.0359507986281077 255.790985573831 334.472086510443 0.764760336931268 0.445077252287043 -834.233336619153 568.484236006995 -1.46746960386935 0.143403679110365 DPYSL2 other 1 1 1 0.764760336931268 -1.46746960386935 0.347264319236543 64.7122308881141 69.822851074049 0.926805907989707 0.354845930003491 -195.265054091939 192.557755662749 -1.01405966962936 0.311452161826988 TGFB2 other 1 1 1 0.926805907989707 -1.01405966962936 1.98253141860563e-09 95.7464737806962 15.5935527928259 6.1401320823274 2.89782046936368e-09 -67.5128434580648 42.8721589790133 -1.57474792652998 0.116472763272527 GPATCH2 other 2.10842216368709e-05 1 3.6805217781388e-05 6.1401320823274 -1.57474792652998 7.4114336884824e-16 337.54582682599 62.4807267143287 5.40239918093943 1.43247522478783e-07 -610.12426451894 139.57137113909 -4.37141413414159 1.75659500303723e-05 NUP50 other 1.00135880565086e-11 0.268741469514665 0.00167843122088391 5.40239918093943 -4.37141413414159 8.57703573219468e-43 385.937988560724 23.4125902672022 16.4842071789625 2.51371907018802e-42 68.7695809150633 92.6064214231284 0.742600565471026 0.458391361580754 CDC45 essential 1.36280520748841e-38 1 3.99631057778492e-38 16.4842071789625 0.742600565471026 0.0686970927066118 -236.314471780029 110.741532528835 -2.13392813322767 0.0337882165857198 -522.917185238785 318.013266641264 -1.64432506467934 0.101322271540645 ADA2 other 1 1 1 -2.13392813322767 -1.64432506467934 0.747080086085958 -2.61694599015144 9.37353372091315 -0.279184570949247 0.780315342353102 10.2863295024963 17.5286638614549 0.586829069448679 0.557805246783633 VNN3 other 1 1 1 -0.279184570949247 0.586829069448679 2.10062155196977e-06 195.844138000479 56.0709059264194 3.49279425335986 0.000557703726730454 -262.854174423087 104.399192778687 -2.51777975889435 0.0123844243236876 ECHDC1 other 0.0182138802321692 1 1 3.49279425335986 -2.51777975889435 2.03817420635927e-18 329.669983558687 35.5579177214494 9.27135233680522 5.8798092745836e-18 36.1038453044082 110.986012953129 0.325300858583462 0.745203464421162 LRRFIP2 other 2.90990131441913e-14 1 8.8790999855487e-14 9.27135233680522 0.325300858583462 0.00106794151297527 132.67175572519 42.3452419469096 3.13309712320282 0.00191877757037693 -100.828068115093 111.306228620384 -0.905861867433963 0.365810693408556 SEC22C other 1 1 1 3.13309712320282 -0.905861867433963 4.15451617869342e-21 156.590234375 15.0624355597507 10.396076634076 1.5168408639296e-21 78.6107177734381 47.0418605798391 1.67108011469956 0.0958517480829169 XYLB other 6.15782388005939e-17 1 2.33836187583388e-17 10.396076634076 1.67108011469956 0.0683769710025436 -392.685611534785 298.955042268966 -1.31352730682994 0.190108154924281 -1122.35011227961 484.511111699713 -2.31645897313333 0.0212738280949989 GABRP other 1 1 1 -1.31352730682994 -2.31645897313333 0.403766613082121 -145.989267419968 234.043604924929 -0.623769521353916 0.533303638541682 369.280536961427 457.843224985275 0.806565472216617 0.420624124546526 KRT31 other 1 1 1 -0.623769521353916 0.806565472216617 2.0256888949192e-29 240.697387302694 20.2123794442597 11.9084142451646 1.64543604677606e-26 -206.788406416612 89.1374232728926 -2.31988315147425 0.0211015813259657 CDC6 essential 3.16655688053769e-25 1 2.5797146341355e-22 11.9084142451646 -2.31988315147425 1.31287234793322e-17 249.350111153219 32.7705871383144 7.60896074582948 4.53949503814424e-13 -76.795398373921 53.9988659402602 -1.42216687400215 0.156123510643015 CDC23 essential 1.84708010630725e-13 1 6.44789875218007e-09 7.60896074582948 -1.42216687400215 3.44766582523981e-16 235.97847692992 33.1100743601418 7.12708991115988 9.15852191112157e-12 -247.879308569228 89.1283265535476 -2.78115070880753 0.00579384400458964 AAAS other 4.69778945347177e-12 1 1.26195273413344e-07 7.12708991115988 -2.78115070880753 0.922411409251468 -56.3049715971298 170.421641021631 -0.330386277585387 0.7413643258324 -139.250947425828 564.955891228121 -0.246481096290755 0.805497124368185 FMO2 other 1 1 1 -0.330386277585387 -0.246481096290755 2.90439971827968e-09 328.049153792565 51.6471745638244 6.35173475728415 8.99372250679302e-10 -136.38229162398 165.597913300537 -0.823574940684582 0.410907978258923 SUCO other 3.05746158343302e-05 1 1.16405750405422e-05 6.35173475728415 -0.823574940684582 1.57952549786817e-09 308.925937348095 46.7002875202991 6.61507570405889 2.01952880542361e-10 132.958557840153 221.617005897198 0.599947451243107 0.549050076080674 MSH2 ts 1.68851275722108e-05 1 2.67325027973923e-06 6.61507570405889 0.599947451243107 1.53429176455934e-08 174.918330842924 54.2711903686131 3.22304209019313 0.00142348603328372 -264.155452898261 99.0969714579055 -2.6656258916093 0.00814594585573976 MAP3K1 other 0.000154441809020543 1 1 3.22304209019313 -2.6656258916093 2.62921587825399e-19 286.179147510947 36.692916497241 7.79930228583671 1.36265706451775e-13 -161.375972523516 81.9618611372178 -1.96891542339853 0.0499853972318196 DHPS essential 3.80473829742135e-15 1 1.95064358785715e-09 7.79930228583671 -1.96891542339853 2.4301051627443e-08 273.605178223398 68.1013149603195 4.01761960665251 7.6280037659696e-05 -338.025349212138 152.119565651298 -2.22210303957211 0.0271052386997727 HOOK2 other 0.000241819764744685 1 0.724584077729452 4.01761960665251 -2.22210303957211 1.00032127484695e-28 1352.35994392306 143.843377022919 9.40161425511845 2.36035368628169e-18 -680.876006241897 255.659495130016 -2.66321423303928 0.00820303174922549 ARCN1 essential 1.55880064259401e-24 1 3.57593583471676e-14 9.40161425511845 -2.66321423303928 2.97799801956191e-13 206.808611401018 39.9409991129966 5.17785273262541 4.38119516151796e-07 -240.55004897645 77.4297799802453 -3.10668645885113 0.00209294874937331 EPB41L4B other 3.73708971474824e-09 1 0.00497747582300055 5.17785273262541 -3.10668645885113 2.05028398715127e-13 153.172469847486 36.1379176800653 4.23855273575932 3.08774648380766e-05 -297.445417690038 71.1921782693626 -4.17806316537504 3.96930268667708e-05 TMEM38B other 2.58909861897463e-09 0.601269970977844 0.304297415979245 4.23855273575932 -4.17806316537504 1.9196307109096e-16 195.906682679378 37.5758772834518 5.21362897801602 3.66958089233246e-07 -327.086011907521 71.865103344957 -4.55138859729301 8.04234883825515e-06 PSMD5 other 2.63046996315943e-12 0.124013019085894 0.0041899274628652 5.21362897801602 -4.55138859729301 0.568242774913911 3.89687323170825 56.5952732709251 0.0688551005497169 0.945155363699376 107.198048377601 108.180580239161 0.990917668777627 0.322603237652117 PTGS1 other 1 1 1 0.0688551005497169 0.990917668777627 2.87908098358951e-20 626.471759625234 85.4769802485484 7.32912835483414 2.6707534180694e-12 -572.595749558052 159.298477017317 -3.59448351471562 0.000386037581989682 NUP188 other 4.22188435433565e-16 1 3.72730347025766e-08 7.32912835483414 -3.59448351471562 2.25381694197155e-06 144.125058214551 60.7184240540757 2.37366269727609 0.0183126150562753 -368.679596022833 113.519323922388 -3.24772543813681 0.00131039526543463 CRAT other 0.019486501280286 1 1 2.37366269727609 -3.24772543813681 0.948658429071499 -8.61800440314953 52.4755573733866 -0.164228925513428 0.869672902376954 18.1854248292845 97.6903775879825 0.186153695771175 0.852462989169881 SH2D3C other 1 1 1 -0.164228925513428 0.186153695771175 2.44366488759138e-08 155.174472870623 44.1274662928188 3.51650538557832 0.000512751522703226 -260.579382435523 85.5873836647048 -3.04460039877329 0.00256000173791182 NANS other 0.000243144656315343 1 1 3.51650538557832 -3.04460039877329 2.49547597545069e-09 294.308714266184 102.882183387845 2.8606383007707 0.00455837723110093 -819.082192273653 199.998927451847 -4.09543292411335 5.57364673311617e-05 TBC1D2 other 2.63796765364893e-05 0.839669880343951 1 2.8606383007707 -4.09543292411335 0.530627460411227 45.4947428500908 42.4743657676966 1.07111058700472 0.285069196131344 11.4478980655909 78.7397149107892 0.145389122611902 0.884511332046207 WHRN other 1 1 1 1.07111058700472 0.145389122611902 9.68283351513189e-16 223.91825655516 32.0662614432596 6.982986056899 2.21487988474807e-11 -22.9786352360089 45.9764351919877 -0.499791581057885 0.617625901626017 CWF19L1 other 1.30466498782887e-11 1 3.01688789101534e-07 6.982986056899 -0.499791581057885 1.36053792768087e-06 58.0826592949043 19.6684566713713 2.95308677571267 0.00342100807456047 -53.4797902233143 28.073954037083 -1.90496109499477 0.0578397497942367 SEMA4G other 0.0119917812945792 1 1 2.95308677571267 -1.90496109499477 2.58127224321764e-07 157.781296244195 59.101465031221 2.6696681065494 0.00805106485176968 -193.371930907899 85.1310331940362 -2.27146228176455 0.0239033279213669 BTAF1 other 0.00240626198512749 1 1 2.6696681065494 -2.27146228176455 2.95883909104477e-09 48.3435839880284 24.983314438967 1.93503484520156 0.0540188377668214 -141.432389421278 34.7096350937011 -4.07472994283781 6.04417112795054e-05 IKZF5 other 3.1132904915973e-05 0.909466429622718 1 1.93503484520156 -4.07472994283781 4.50024082048179e-05 35.3210228583133 27.8944894684096 1.26623657688068 0.206511747668895 -138.403118225191 43.837838257615 -3.15716111300604 0.00177242833798259 BLNK other 0.346068519095049 1 1 1.26623657688068 -3.15716111300604 0.0583184151573486 2.92149542497138 11.7033162223196 0.249629709175912 0.803062137831947 -35.6586865289829 18.3924528969348 -1.93876731552894 0.0535639868260578 TLL2 other 1 1 1 0.249629709175912 -1.93876731552894 0.831158625924343 -24.1378158186936 50.7786849593519 -0.475353306963657 0.634916670111872 9.73958283662881 86.4145904242055 0.112707620192581 0.910345495080404 CYP26A1 other 1 1 1 -0.475353306963657 0.112707620192581 0.0207210885903066 35.026720183486 18.2078720551569 1.92371300047474 0.0554340938373387 71.2220183486235 25.6816080398786 2.77326942448578 0.00593346469346971 TDRD1 other 1 1 1 1.92371300047474 2.77326942448578 0.0866248489489493 -76.5350291561028 63.9701732171339 -1.19641741310157 0.232575535448831 -223.171575828136 100.538224622069 -2.21976841810223 0.0272592074714391 SORBS1 other 1 1 1 -1.19641741310157 -2.21976841810223 0.542961771417661 -76.0268920538384 127.524366494931 -0.596175414499003 0.551552036032994 -224.347475476803 203.126452096415 -1.10447198364059 0.270360946634978 CRTAC1 other 1 1 1 -0.596175414499003 -1.10447198364059 0.0153550373188741 437.197306375132 154.133404597028 2.83648640291931 0.00490292314333378 245.560651563049 266.461830876079 0.921560325378271 0.357571633688499 BAMBI other 1 1 1 2.83648640291931 0.921560325378271 0.0357577584576172 7.83410829088297 9.17441775355248 0.853907953760824 0.393915758917454 -38.0500354457509 20.3531293975062 -1.86949312327435 0.0626406030424951 IL11 other 1 1 1 0.853907953760824 -1.86949312327435 0.0418110558285513 29.5891624696884 17.5135051210224 1.6895054568015 0.092272659072623 -19.5591657340049 28.935124100207 -0.675966194797311 0.499638551719016 MYO3A other 1 1 1 1.6895054568015 -0.675966194797311 9.24175866270011e-23 730.267187829295 114.129778514617 6.39856834328094 6.79449823670774e-10 -861.516092377942 197.304599998906 -4.36642679584114 1.79447682318695e-05 WAC essential 1.39227094253577e-18 0.274483174874676 8.82945045860171e-06 6.39856834328094 -4.36642679584114 0.00575985881302809 105.903294217447 38.2734130768615 2.7670198632343 0.00605255848560103 4.01350205004959 63.6392962591833 0.0630664115722436 0.949760807711636 CREM other 1 1 1 2.7670198632343 0.0630664115722436 4.4338278633735e-16 310.769323235679 51.6839580545033 6.01287778517188 5.89688821958039e-09 -197.74068863904 94.7082520308833 -2.08789291744672 0.0377447176361066 NUBP2 essential 6.02379853517924e-12 1 7.39233907206598e-05 6.01287778517188 -2.08789291744672 0.409182364091308 -23.3687257929172 21.8069552971195 -1.07161799868521 0.28484154746889 -50.4367086411779 39.8747274862893 -1.26487908057855 0.206997297338737 TPSD1 other 1 1 1 -1.07161799868521 -1.26487908057855 0.344149454609987 2.74455061212302 6.37496149037115 0.430520343733595 0.66715936187255 -9.62385651076304 10.6994629464722 -0.899470988301909 0.369200378035262 SMIM24 other 1 1 1 0.430520343733595 -0.899470988301909 0.00220657578359917 125.046771323139 49.3322391741394 2.53478806996238 0.011814582328382 -130.55942756993 95.0538302707635 -1.37353147367158 0.170722372754091 HIVEP1 other 1 1 1 2.53478806996238 -1.37353147367158 0.257581472964649 -41.7305937787457 25.3368830150521 -1.64702950058831 0.10070252860399 -26.5680592346097 53.0208517873134 -0.501086993871472 0.616713683044785 TREM2 other 1 1 1 -1.64702950058831 -0.501086993871472 0.719080515215509 3.91805513453435 23.5166373796629 0.166607796483806 0.867805233753934 -42.1575699015532 59.5295408712925 -0.708178986172614 0.479454205643465 CRISP3 other 1 1 1 0.166607796483806 -0.708178986172614 0.146861563750903 225.960341838624 148.576046269394 1.52083964752245 0.129457434354975 -165.497784613054 291.262990009297 -0.568207394313201 0.570361204531409 FKBP5 other 1 1 1 1.52083964752245 -0.568207394313201 9.64486321935284e-18 709.440135286292 82.2287165050096 8.62764451933372 5.23770042092357e-16 -77.8718905439741 161.005193026273 -0.48366073839163 0.629014372106748 SRPK1 other 1.36021505982533e-13 1 7.76174825376663e-12 8.62764451933372 -0.48366073839163 1.00649243041687e-13 310.798378203992 41.9797155068184 7.40353702858019 1.65058777974991e-12 -35.0685990887481 82.1969803937235 -0.426640965650678 0.669977093921268 BRPF3 other 1.28257330408022e-09 1 2.31428912598735e-08 7.40353702858019 -0.426640965650678 8.86251008095571e-32 332.710497839353 26.8653029876286 12.3843940264722 3.54312640465362e-28 -100.097201866987 65.3562343821215 -1.53156317546914 0.126805420682824 MRPS18A essential 1.39300933452462e-27 1 5.57192058395829e-24 12.3843940264722 -1.53156317546914 0.279876369563353 -278.853841376078 206.601299678805 -1.34971968622463 0.178228139303198 138.225844218897 441.08658155975 0.313375763393457 0.754235365491845 PGC other 1 1 1 -1.34971968622463 0.313375763393457 0.00743702381869636 210.464080268881 88.9249101733901 2.36676179777419 0.0186610364867594 -255.108012746914 212.429008373617 -1.20090949301158 0.230854581680382 TMEM14A other 1 1 1 2.36676179777419 -1.20090949301158 0.000353705868986936 64.5157667368655 21.2063408590532 3.04228660501433 0.00258086683391458 -75.7873893118034 50.7459816002479 -1.49346582570457 0.136491650742084 EFHC1 other 1 1 1 3.04228660501433 -1.49346582570457 4.25756256299467e-34 15399.7007514661 1144.32252790831 13.4574828126603 6.50316228682741e-32 -722.358830656262 2651.97001364349 -0.272385746045381 0.785534394560632 HSP90AB1 other 6.71673069938039e-30 1 1.02782479943307e-27 13.4574828126603 -0.272385746045381 3.49946909653971e-35 547.209357622667 40.2488022818865 13.5956681093323 2.00443368724049e-32 -51.0819202421696 93.5605121525088 -0.545977347354654 0.585532331305426 CDC5L essential 5.5295111194424e-31 1 3.16981143300211e-28 13.5956681093323 -0.545977347354654 0.000112227794722565 603.803816359735 254.402464763031 2.37341967941294 0.0183218163100934 -1043.32262102638 468.605838759079 -2.22643965296979 0.0268069507397594 ITPR3 other 0.826669935926416 1 1 2.37341967941294 -2.22643965296979 2.87417747818990e-09 73.3021456793292 13.1731400541862 5.56451577815231 6.3109021546035e-08 -21.5777999629161 22.9326153257421 -0.940921899068996 0.347582839325125 ZNF184 other 3.02650888453396e-05 1 0.000753711044324296 5.56451577815231 -0.940921899068996 0.00135715614224069 5631.08619928072 2126.62226598853 2.6479014582607 0.00858117198102159 -5106.01762160272 3839.62025942264 -1.32982359624556 0.184711322692096 DSP other 1 1 1 2.6479014582607 -1.32982359624556 1.64251506588789e-09 61.5457023874404 26.3320435992519 2.33729304584582 0.0201496124971116 -142.343968619429 41.1467698638523 -3.45942024344612 0.000628249128375401 SIRT1 other 1.75387758735509e-05 1 1 2.33729304584582 -3.45942024344612 1.71774178676176e-05 398.092540761805 131.694691222994 3.02284425488138 0.00274299065132324 -222.846272356068 205.787717600376 -1.0828939401953 0.279814528396285 HNRNPH3 other 0.137969020312705 1 1 3.02284425488138 -1.0828939401953 8.31844761021523e-18 92.2467249063499 11.4750100043912 8.03892326638925 4.06784412774305e-14 -53.0890761499254 32.3574973753613 -1.64070402398766 0.102163309904152 IFT74 other 1.1747311715146e-13 1 5.87071264515877e-10 8.03892326638925 -1.64070402398766 3.4702284763393e-09 252.022722981053 53.8391112671306 4.68103423421321 4.54477150949413e-06 -474.173125476453 189.107118477411 -2.50743139282244 0.0127553722672942 JAK2 og 3.63159410048908e-05 1 0.0479609737396915 4.68103423421321 -2.50743139282244 0.249112875544628 -11.3059255342461 8.90169293107454 -1.2700871195836 0.205135037996615 -31.4563967674767 20.3913286820746 -1.54263595364087 0.12407746203995 IL12RB1 other 1 1 1 -1.2700871195836 -1.54263595364087 3.72357769453543e-08 387.734242657938 81.9864958056557 4.7292452110289 3.61726419118017e-06 -249.243562628326 159.229467898781 -1.56531052899559 0.118668503709636 ABL1 og 0.000366251102034505 1 0.0384696046732011 4.7292452110289 -1.56531052899559 2.83290786551083e-06 291.036995506358 96.8192896903747 3.00598151914857 0.00289828851052176 -280.103445353493 152.213815901309 -1.84019724947376 0.0668449499219421 ACOT7 other 0.0242780204074278 1 1 3.00598151914857 -1.84019724947376 7.02501692796915e-10 147.429492133198 105.495032833155 1.3975017417774 0.163397385588258 -947.304929147338 188.996485571553 -5.01228859511619 9.68494458588372e-07 SH3GLB1 other 7.65937595656477e-06 0.0151675917159525 1 1.3975017417774 -5.01228859511619 8.3570063391433e-11 170.197805035411 26.8041800739947 6.34967398986161 9.0116683275293e-10 22.0252301921025 47.4385049075679 0.464290142259285 0.642811274919084 CDC7 essential 9.54197075768346e-07 1 1.16619999826557e-05 6.34967398986161 0.464290142259285 2.14950248364157e-07 56.7435985261808 11.8990457455318 4.76875202765637 3.02025829055176e-06 -3.80575141779251 20.4254512565901 -0.186323982270141 0.852329078724497 SYDE2 other 0.00201577789371101 1 0.0323409257752283 4.76875202765637 -0.186323982270141 9.78646358241665e-07 108.348531304305 41.9771531910307 2.58113099788424 0.0103737843546428 -234.483067765236 78.9068228062745 -2.97164502923808 0.00322804251487938 PCSK5 other 0.00871876040557499 1 1 2.58113099788424 -2.97164502923808 8.26693405986412e-06 7591.51641988627 1597.46420450783 4.75222943867164 3.26285356490364e-06 3659.12298116608 2290.43568424821 1.59756635225805 0.111300555489505 SCD essential 0.0681608713235797 1 0.0348179103910868 4.75222943867164 1.59756635225805 6.36327280346011e-14 200.015715585598 27.5900119874494 7.24956972387634 4.44371250137672e-12 1.21241648251673 52.9385249062938 0.0229023472917469 0.98174514727975 TMED1 other 8.16217002499828e-10 1 6.1656510956602e-08 7.24956972387634 0.0229023472917469 0.00348663614768787 -45.8379587155911 356.569314695118 -0.1285527296559 0.897806571217351 -1440.39587155963 502.92935667101 -2.86401231595207 0.00450908098196614 ABLIM1 other 1 1 1 -0.1285527296559 -2.86401231595207 8.91210087630643e-09 903.697468881098 160.262536496025 5.6388566450994 4.38084259560209e-08 -343.971295098851 561.187096521072 -0.612935146284026 0.540444883074416 ERMP1 other 9.11173193593569e-05 1 0.000527672490640271 5.6388566450994 -0.612935146284026 1.47446481706681e-07 639.552655165579 137.02056458226 4.66756692409939 4.79778718211708e-06 -95.5790462026562 226.605224406649 -0.421786595842719 0.67351517719662 RAB18 other 0.00139631818176227 1 0.0505542835379677 4.66756692409939 -0.421786595842719 0.112757002382818 208.641906153595 161.039633136264 1.29559352620391 0.196209953942623 -204.295889013604 278.785986223879 -0.732805446144426 0.464305822113355 NRP1 other 1 1 1 1.29559352620391 -0.732805446144426 0.000101622099097843 53.5628890064266 25.4946710591345 2.10094450256637 0.0365661430471896 -85.3164758189023 42.018444013707 -2.03045300275924 0.0432833310018017 PRTFDC1 other 0.752816510116823 1 1 2.10094450256637 -2.03045300275924 0.0221533986618062 26.6155457331415 64.5854531295513 0.412098149714204 0.680590879127835 -212.875369152362 103.303219067254 -2.0606847596276 0.0402804117624608 PALMD other 1 1 1 0.412098149714204 -2.0606847596276 4.15261603871028e-06 -38.4166691209736 83.7146410147113 -0.458900243199067 0.646672290918418 -561.748862763157 131.590549736249 -4.26891493263831 2.71600780637798e-05 TSPAN15 other 0.0351518947676825 0.413294907896537 1 -0.458900243199067 -4.26891493263831 5.3759599644589e-07 335.575562455738 83.8239427931936 4.00333784445876 8.06132679124394e-05 -60.4083760963129 131.181937913556 -0.460493091176315 0.645530263355527 H2AFY2 other 0.00489534914363628 1 0.763730100202451 4.00333784445876 -0.460493091176315 5.67859408578119e-16 142.170033698613 56.4344140027141 2.51920811460496 0.0123375979356241 -477.535251445137 87.4472910489965 -5.46083527250233 1.07193003978012e-07 WASHC2A other 7.69563070505066e-12 0.00169332788384066 1 2.51920811460496 -5.46083527250233 0.000944342616954871 32.5340221606121 17.302849696175 1.88026959326845 0.0611359756944165 -82.414331143102 39.6360667597921 -2.07927622189559 0.0385253842908138 MAST3 other 1 1 1 1.88026959326845 -2.07927622189559 1.38586832441424e-06 26.9770253322273 19.3423248550557 1.39471472712733 0.164301533160699 -197.521636234087 46.8245438714022 -4.21833551174691 3.40998261562895e-05 MZF1 other 0.0122039564647918 0.517260262964755 1 1.39471472712733 -4.21833551174691 0.873304947354113 2.51803442510077 10.0154650382483 0.25141462882498 0.801683397345907 -6.59302606471927 22.2991574326128 -0.295662564141409 0.767713372328693 OCEL1 other 1 1 1 0.25141462882498 -0.295662564141409 7.60069383752621e-08 181.460156978458 77.0006322730697 2.35660606441439 0.0191520674969474 -649.742918855122 171.43978985605 -3.78991901122068 0.000185604015832544 MYO9B other 0.000733238934506153 1 1 2.35660606441439 -3.78991901122068 0.00293883553342908 71.6873410567959 26.899127798303 2.66504332758769 0.00817029517354987 -238.242759254026 145.377305462766 -1.63878920781789 0.102443827429824 KCNK6 other 1 1 1 2.66504332758769 -1.63878920781789 0.124956612922542 13.9450331229789 7.28109442490825 1.91523860414084 0.0565384037786823 -13.3995027628646 39.3509371846589 -0.34051292603238 0.733740069543593 CATSPERG other 1 1 1 1.91523860414084 -0.34051292603238 4.97843141181042e-21 894.322134799896 90.3113739617539 9.90265229691483 6.95809169060425e-20 -839.164809155503 483.725869303771 -1.73479415182677 0.0839356028617524 PSMD8 other 7.37405260717359e-17 1 1.06486635233007e-15 9.90265229691483 -1.73479415182677 2.55050257797912e-10 267.178664018587 49.5298216101475 5.39429893613524 1.52076790811674e-07 -114.282635936631 102.829797678302 -1.11137664876244 0.267409774902188 FBXL19 other 2.84559572625131e-06 1 0.00177914637570577 5.39429893613524 -1.11137664876244 0.257301375142633 5.04840009736284 5.59150999415727 0.902868831968118 0.367409320842626 -8.77681168673112 11.60433263868 -0.756339201918079 0.450112664027557 STX1B other 1 1 1 0.902868831968118 -0.756339201918079 0.00133916181058154 49.5671424410139 38.808611265578 1.27722020511923 0.202634050426782 -191.026507427906 80.5413984490006 -2.37178036521014 0.0184121346089843 HSD3B7 other 1 1 1 1.27722020511923 -2.37178036521014 3.51988424715193e-11 246.925025754511 50.5542902685552 4.88435352257528 1.79351947271764e-06 -236.40901980236 104.956716400138 -2.25244298707927 0.0251097877263088 SETD1A essential 4.08412169197039e-07 1 0.0195314270578951 4.88435352257528 -2.25244298707927 1.33165688658703e-10 271.309113457071 55.7498324426599 4.86654580955234 1.94461343189618e-06 -238.025936965827 116.050780106074 -2.05104986582826 0.0412379536315605 BCL7C other 1.504905447532e-06 1 0.0211360033912796 4.86654580955234 -2.05104986582826 5.32278780061875e-07 310.374144367929 207.443270823322 1.49618805727505 0.135768318445313 -1311.34541703921 361.189843247332 -3.63062650170161 0.00033797111156298 CIRBP other 0.00485065652270387 1 1 1.49618805727505 -3.63062650170161 1.17115614439755e-09 104.261720060155 59.2502876956903 1.75968293345078 0.0795940377824658 -455.646152061105 103.232776279996 -4.41377407912839 1.47001202519338e-05 ATP5D other 1.25992978014289e-05 0.225338143341893 1 1.75968293345078 -4.41377407912839 0.85664088134069 2.1111429120847 6.5754078514269 0.321066458505166 0.748408407936859 -2.32569439164987 11.4764816632988 -0.202648726315429 0.839562222581988 CBARP other 1 1 1 0.321066458505166 -0.202648726315429 0.0946224083067326 -0.955854914678329 2.78253829489705 -0.343519051087739 0.731475351676731 -10.0349099378894 5.09886138830135 -1.9680687851043 0.0500832752909006 IGFALS other 1 1 1 -0.343519051087739 -1.9680687851043 1.03726930059471e-06 171.866184667246 149.890249538039 1.1466135068621 0.252549045720429 -1417.32905847406 345.763781894897 -4.09912527768711 5.4797406664946e-05 HNRNPM essential 0.00922236135158761 0.825851715847401 1 1.1466135068621 -4.09912527768711 1.25773649226566e-16 261.870898941406 31.234772789461 8.38395402158214 2.79069824328292e-15 48.0334135702311 71.8592832485007 0.668437137121505 0.504421443916343 MARCH2 other 1.73102273430523e-12 1 4.09758223061231e-11 8.38395402158214 0.668437137121505 7.82074087505795e-12 451.495309336588 72.1064252698304 6.26151286306375 1.48750039639974e-09 -211.603622130516 178.023553742598 -1.18862710962658 0.235626976594512 NDUFB7 essential 9.31059201175649e-08 1 1.91039675909619e-05 6.26151286306375 -1.18862710962658 5.48594856918522e-12 190.855300781569 65.1812619068632 2.92807004955321 0.00369937243226408 -436.391618556139 108.101405857707 -4.03687274086479 7.04807960770737e-05 TIMM13 essential 6.56558324760088e-08 1 1 2.92807004955321 -4.03687274086479 5.98311806155775e-09 228.346667693832 46.7589047322298 4.88349051376386 1.78699049588045e-06 -66.0262759382222 82.253457754714 -0.802717329344591 0.422844150618149 CDC34 other 6.18115926939532e-05 1 0.0194656874716258 4.88349051376386 -0.802717329344591 5.23064380684964e-18 428.559939424973 45.177379652749 9.48616194031287 3.78514449672287e-18 35.4921918710051 146.214470736707 0.242740624044778 0.808429451379536 MTAP other 7.41234533868662e-14 1 5.72616659464237e-14 9.48616194031287 0.242740624044778 0.0081089118983425 -56.2382097351542 70.1890304940354 -0.801239301060489 0.423697658776004 260.649269572318 123.469326059857 2.11104472576417 0.0356877253668056 MISP other 1 1 1 -0.801239301060489 2.11104472576417 1.68175358222691e-14 924.305562018756 119.582382358738 7.72944595840137 2.2017616964779e-13 -0.336089000957503 287.768137179449 -0.00116791596266241 0.99906901021719 CEP170B other 2.19149309299989e-10 1 3.14433587874008e-09 7.72944595840137 -0.00116791596266241 1.13227483967853e-20 476.779079982003 102.095535151905 4.66993075919152 4.74698553654216e-06 -937.644923558404 177.517166983075 -5.28199576127645 2.62675131535902e-07 POLR2E essential 1.66931279613806e-16 0.0041381840222166 0.0500284805696178 4.66993075919152 -5.28199576127645 2.92025758160484e-19 206.625914549129 43.6986169673547 4.72843144448921 3.64884047877404e-06 -374.126289067149 76.8701141578757 -4.86699276000513 1.9296315301686e-06 POLRMT essential 4.22298448875875e-15 0.0300752370292078 0.0387944719703256 4.72843144448921 -4.86699276000513 0.51982842958834 6.97416205436251 6.1769272565443 1.12906656735735 0.259871900412723 8.39674315803876 10.8658153577303 0.772766965165211 0.440336253871801 HCN2 other 1 1 1 1.12906656735735 0.772766965165211 0.138446107040803 -5.28086684830305 11.3953805811899 -0.463421718184653 0.643434079383472 -36.3110501982597 19.3515941278501 -1.87638547803161 0.0616769863978897 IZUMO4 other 1 1 1 -0.463421718184653 -1.87638547803161 0.0146996404140993 5.55942888886202 61.5022228742533 0.0903939504792982 0.928040692494064 -210.778052643399 99.1050326050572 -2.12681482567458 0.0343356031146583 RASSF7 other 1 1 1 0.0903939504792982 -2.12681482567458 0.0876957613971496 55.649860522071 188.867486055577 0.29465029521119 0.768486620344839 617.838585683478 313.940493726736 1.9680117666543 0.0500860918467856 GADD45B other 1 1 1 0.29465029521119 1.9680117666543 0.933753130364099 11.7001222834786 53.0375899005169 0.220600564720693 0.825570179461548 34.4728070261099 93.2982751686874 0.369490292974672 0.712051925947743 PALM other 1 1 1 0.220600564720693 0.369490292974672 1.11087007580415e-08 865.361092109333 342.404904139384 2.52730344001459 0.0120633202350772 -2083.25069613789 603.540049093266 -3.45171906863129 0.000646014946969419 MKNK2 other 0.000112853291000943 1 1 2.52730344001459 -3.45171906863129 4.79640069894512e-32 250.058741123715 18.6492789652291 13.4084937862713 1.53183956875144e-31 -6.18373046064448 82.2632335366837 -0.0751700388471475 0.940137005467372 ARVCF other 7.54377901930089e-28 1 2.42061288654102e-27 13.4084937862713 -0.0751700388471475 2.89941897943346e-45 397.004391768088 23.693272003699 16.7559968798783 3.0933683089485e-43 -123.907938785929 104.525823685533 -1.18542896307334 0.236930184271206 TRMT2A other 4.61152588678892e-41 1 4.9193836217208e-39 16.7559968798783 -1.18542896307334 3.406249478063e-60 964.570842763606 44.991241802092 21.4390802326944 2.0533255695237e-59 101.541392935872 198.484473029494 0.51158355807904 0.609376697429737 RANBP1 other 5.42990229298023e-56 1 3.27341162293468e-55 21.4390802326944 0.51158355807904 5.55717763302849e-51 731.876257590493 38.9821005788027 18.7746747025856 4.19365785582459e-50 23.3453496682137 173.536798972857 0.134526796658646 0.893091316207345 ZDHHC8 other 8.84924966283456e-47 1 6.67798076961507e-46 18.7746747025856 0.134526796658646 1.47844607070741e-18 103.915163898019 12.3789342916805 8.3945161553897 3.55907351243873e-15 -142.148174469219 52.7812837065908 -2.69315493081631 0.00755874652463669 KLHL22 other 2.11506494875402e-14 1 5.21866949128891e-11 8.3945161553897 -2.69315493081631 2.30987781758345e-29 1036.29437569733 82.3862066946653 12.5784936250067 2.14857908037096e-28 -137.490947357744 351.310041739658 -0.39136640295535 0.69586246584651 MED15 other 3.60964606553765e-25 1 3.38035946714763e-24 12.5784936250067 -0.39136640295535 0.746107567540013 -27.2082503036379 35.591496828058 -0.76445928742701 0.44532625251969 -38.3052406793984 151.606680969843 -0.252661956810583 0.800740440020688 SERPIND1 other 1 1 1 -0.76445928742701 -0.252661956810583 7.4717119940628e-51 272.198870361111 15.0342857752898 18.1052079513145 3.83626560355582e-47 -139.782248217122 64.0405256950858 -2.18271550240956 0.0300027601024745 SNAP29 other 1.18972070081462e-46 1 6.10541670805909e-43 18.1052079513145 -2.18271550240956 1.57507380224729e-32 1007.64204827699 82.9079418170931 12.153745783486 6.22124447699319e-27 -1287.47924821794 353.15732703384 -3.64562519212456 0.000325468406991045 CRKL other 2.47979619425814e-28 1 9.76299895774541e-23 12.153745783486 -3.64562519212456 2.27916923809987e-34 561.572182611767 39.3658438793546 14.2654679100194 4.72999344493558e-34 88.120718175938 167.684010676986 0.525516522536472 0.599697528104759 LZTR1 other 3.59721280849302e-30 1 7.49183661743346e-30 14.2654679100194 0.525516522536472 0.396002292912576 250.213110710815 435.747120464812 0.574216326303916 0.566297724420399 -1159.81439108512 1220.80435086521 -0.950041167745787 0.342937814534271 MMP11 other 1 1 1 0.574216326303916 -0.950041167745787 1.23683177367139e-06 123.065154397452 33.2989937830426 3.69576195603011 0.000267322218516381 -215.802446469651 95.6238550534428 -2.25678463129355 0.0248521259959211 CECR2 other 0.0109360665428024 1 1 3.69576195603011 -2.25678463129355 1.75034771825565e-26 756.594622976317 76.3006772150941 9.91596209354016 5.64152562612988e-20 -684.614475257399 214.634261326371 -3.18967936911237 0.00159165994861497 SMARCB1 other 2.70113659881212e-22 1 8.63717573360484e-16 9.91596209354016 -3.18967936911237 1.43470355395277e-36 58.240692041466 3.8039429614451 15.3106112872262 1.2771138679776e-37 53.8030146814719 16.2033973948702 3.32047738942113 0.00103503875195371 P2RX6 other 2.27070531484105e-32 1 2.02729055402765e-33 15.3106112872262 3.32047738942113 0.00569910535996963 -215.676647632939 66.4634572294855 -3.24504105900253 0.00132177251030689 -200.794643334677 186.96210267483 -1.07398579959226 0.283784384973826 DERL3 other 1 1 1 -3.24504105900253 -1.07398579959226 1.07546503067692e-08 44.0746239499105 7.27691002850877 6.05677736528819 5.16724649238914e-09 0.613944339447931 30.996959258782 0.0198065989093427 0.984213709037044 SLC7A4 other 0.000109374793619842 1 6.49626229023163e-05 6.05677736528819 0.0198065989093427 2.29723336559615e-18 381.301959383078 54.7934232831148 6.95890011129458 2.76264049880583e-11 -589.600546079747 156.58813132872 -3.76529524349465 0.000205568835458601 BCL2L13 other 3.27585477934011e-14 1 3.75221832547807e-07 6.95890011129458 -3.76529524349465 5.50712874406012e-18 367.537802722847 43.6513501085542 8.41984959935574 2.21757966385063e-15 -171.542813526006 122.791508914614 -1.39702504710885 0.163548902857207 DDTL other 7.80029715308676e-14 1 3.2602856217932e-11 8.41984959935574 -1.39702504710885 0.0346119357365265 9.27030741655224 7.12790867277383 1.30056484196573 0.194512322412843 -34.9989295620956 20.7481885018625 -1.68684266382841 0.0927843197045117 GSTT2 other 1 1 1 1.30056484196573 -1.68684266382841 0.0359271049142722 -13.6503514387411 11.0768182135537 -1.23233506008417 0.218888111023947 50.1907221551357 29.3342077199907 1.71099634373052 0.0882218634800541 OSM other 1 1 1 -1.23233506008417 1.71099634373052 5.28662727240375e-15 445.404567159947 66.295319216627 6.7184919300945 1.07811115068045e-10 -527.468137046318 192.158454877587 -2.74496450016907 0.00645632316495048 CABIN1 other 6.9947365441174e-11 1 1.43873933058306e-06 6.7184919300945 -2.74496450016907 7.4042741698319e-12 78.4422877607712 25.8929225175918 3.02948760254765 0.00268444018037142 -460.082746460307 82.1380463337415 -5.60133539810418 5.18748928635814e-08 TBC1D10A other 8.82441395560566e-08 0.000821438928494811 1 3.02948760254765 -5.60133539810418 0.756810964704746 -133.452943251134 281.995286186123 -0.473245298019103 0.636419152393781 313.359568754296 820.764059613352 0.381790071195264 0.702916277325561 SUSD2 other 1 1 1 -0.473245298019103 0.381790071195264 7.48447484758124e-13 520.403936953072 82.5080127494693 6.30731391547689 1.13936648672043e-09 -663.359511139516 261.733567136598 -2.53448389672277 0.0118204354434269 SF3A1 essential 9.26802520375985e-09 1 1.46955489457202e-05 6.30731391547689 -2.53448389672277 0.604862626679552 -1.41195084496892 36.4734001197417 -0.0387117965512813 0.96914867031753 -101.487556772343 106.158001273904 -0.956004781123279 0.339921841376144 GGT5 other 1 1 1 -0.0387117965512813 -0.956004781123279 2.11234662807184e-17 145.632845907075 17.1006700114438 8.51620701467358 1.12284189996865e-15 -64.9073004262607 54.2470872024464 -1.19651217740099 0.232534824288465 RNF215 other 2.96150997255671e-13 1 1.65619180245376e-11 8.51620701467358 -1.19651217740099 0.0344533349693858 16.0974139621996 47.2955889360605 0.340357617366007 0.733848979175985 -353.778556408358 150.032012522819 -2.35802046816208 0.0190781378420943 SEC14L2 other 1 1 1 0.340357617366007 -2.35802046816208 6.05423252681928e-18 405.047759919233 50.819553665261 7.97031321028924 4.42957444986851e-14 -341.359278297175 147.518521374134 -2.31400962480789 0.0214153813128001 SPECC1L other 8.57037156496537e-14 1 6.3905470588253e-10 7.97031321028924 -2.31400962480789 4.15010907628206e-19 339.655802939463 39.5690850756204 8.58386799417646 7.79389642350741e-16 -329.180235870421 137.291018643302 -2.39768223095254 0.017188972553836 PPIL2 other 5.99068245161315e-15 1 1.15154819657322e-11 8.58386799417646 -2.39768223095254 0.000468400381969932 62.2390067329162 15.8255139290313 3.93282689030029 0.000107072707195971 33.0630261010939 54.8933343094514 0.602314042625047 0.547476281426046 YPEL1 other 1 1 1 3.93282689030029 0.602314042625047 5.84619956580459e-29 765.225678121398 69.1524974485747 11.065770671413 9.87823619912201e-24 -501.99820390706 200.194495997468 -2.50755247493622 0.0127422590618128 SNRPD3 essential 9.12007132265516e-25 1 1.53754746439334e-19 11.065770671413 -2.50755247493622 6.48860794492032e-31 984.989946103896 85.0127858513894 11.5863741699484 1.68998373079479e-25 -800.581052346074 269.744823375124 -2.96791998574422 0.00326514820681629 PES1 essential 1.01825724479635e-26 1 2.64330355333613e-21 11.5863741699484 -2.96791998574422 2.76412008106592e-38 1078.77100286559 79.5806506234618 13.5556946872655 3.11392474241975e-32 -919.05982997206 274.594086637409 -3.34697604462853 0.00093398472615807 MAPK1 other 4.38030109246516e-34 1 4.92280362529138e-28 13.5556946872655 -3.34697604462853 2.25648937040621e-14 279.447014051413 37.8150981574114 7.38982648909623 1.82844615488358e-12 -216.87834241995 130.660163043873 -1.65986584868356 0.0980981072026537 PPM1F other 2.93185663896879e-10 1 2.56073883991445e-08 7.38982648909623 -1.65986584868356 3.61327876056916e-23 89.288893285609 8.58975834159138 10.3948085306748 1.57098328002277e-21 -22.2133115519351 27.26021792494 -0.81486184788026 0.415864281624154 SLC35E4 other 5.46327748598057e-19 1 2.4215136278271e-17 10.3948085306748 -0.81486184788026 1.12493121534162e-23 159.53787620199 15.6755886167876 10.1774727636788 8.16616565800368e-21 -99.8638214333532 54.16288901201 -1.84376836714174 0.066308551388853 TOP3B other 1.70775807801012e-19 1 1.25481301500885e-16 10.1774727636788 -1.84376836714174 0.0225884133149915 -72.7370541393315 28.04497821678 -2.59358568857119 0.0100105613625303 -2.60165451167603 66.2405580159948 -0.0392758543949436 0.968699163479401 CYTH4 other 1 1 1 -2.59358568857119 -0.0392758543949436 1.57419994325965e-10 64.8015056561574 11.4283241618532 5.67025442561906 3.64891127482064e-08 -65.2877054329254 33.446016924094 -1.95203230271325 0.0519641277822826 CRYBB2P1 other 1.77317881608766e-06 1 0.000440751992885585 5.67025442561906 -1.95203230271325 0.546958183474079 -28.6552218074485 26.1213940878199 -1.09700200958302 0.273610746153807 -20.1892380704342 61.4499960542016 -0.328547426636552 0.742750586586507 MFNG other 1 1 1 -1.09700200958302 -0.328547426636552 0.0412609737293012 59.2027105414768 41.4479318046653 1.42836344212507 0.15433452263968 -139.726929420956 97.5053336467646 -1.4330183200762 0.153000963999543 CARD10 other 1 1 1 1.42836344212507 -1.4330183200762 1.2001885986406e-06 32.4291412548858 7.75751882036595 4.18034967182406 3.92782888299458e-05 -39.234542084427 22.6998152140841 -1.7284079942679 0.0850499351013623 LRP5L other 0.010622869286568 1 0.383081150958462 4.18034967182406 -1.7284079942679 5.11293271875746e-43 1078.18806042132 67.550572447608 15.9611979788559 1.58825514806149e-40 -325.943911175926 266.685072776724 -1.22220530673951 0.222728407939974 SLC25A1 other 8.12547267664936e-39 1 2.5235786047549e-36 15.9611979788559 -1.22220530673951 1.23674785570949e-05 123.231404082684 37.2459576803862 3.30858465608948 0.00106411445656124 -242.283310540908 109.556616810058 -2.21148952564829 0.0278335361907727 GRK3 other 0.100485763276396 1 1 3.30858465608948 -2.21148952564829 0.0198180752835319 27.8025172714667 15.2548677167807 1.82253414370046 0.0694758931699183 -72.5342423948642 48.6366412752029 -1.49134974153417 0.137032783639115 PLA2G3 other 1 1 1 1.82253414370046 -1.49134974153417 0.0482950513003306 -9.73801058645484 3.94384694315773 -2.46916544348901 0.0141574698145486 -9.49525830129156 9.56422699059713 -0.99278889037521 0.321695197155667 LGALS2 other 1 1 1 -2.46916544348901 -0.99278889037521 6.64327240391558e-12 251.15508396029 47.2524921979326 5.31517116405721 2.22249765870677e-07 -372.624017325484 114.59206398375 -3.25174365808024 0.00129159714935127 GGA1 other 7.92940994131364e-08 1 0.00257343003901657 5.31517116405721 -3.25174365808024 1.22380312797659e-30 271.525203680728 23.6311337625471 11.4901471257831 5.33155497104966e-25 -336.452941758892 93.4708508091218 -3.59954936588699 0.000381374030446806 HIRA other 1.91965758654407e-26 1 8.33322041975061e-21 11.4901471257831 -3.59954936588699 2.07946305350663e-11 397.377929870162 84.0957726866326 4.72530208326782 3.69493569503751e-06 -757.833172603935 203.970587200257 -3.71540418158378 0.000246390114206522 SH3BP1 other 2.43650685979372e-07 1 0.0392734715025537 4.72530208326782 -3.71540418158378 0.662403241269316 77.4247346547055 91.6337389602815 0.844936979907206 0.39888589716931 -4.36681767287772 260.326721550958 -0.0167743735520555 0.98662886647128 SEZ6L other 1 1 1 0.844936979907206 -0.0167743735520555 0.898755271526029 159.143981149722 428.465922791102 0.371427394069124 0.71060944617755 -140.005695164757 1039.22519616605 -0.13472122854726 0.892932291361443 LGALS1 other 1 1 1 0.371427394069124 -0.13472122854726 4.08108059230986e-26 335.854422421576 37.0722253838355 9.05946214299878 2.59485683196173e-17 -454.941927674261 105.320278363358 -4.31960430359574 2.19041324279051e-05 HPS4 other 6.29057762498642e-22 0.334147540187692 3.89617753319053e-13 9.05946214299878 -4.31960430359574 0.00031098370611707 181.699238866532 63.8343540761456 2.84641775570863 0.00475941256849397 -393.123961422461 203.483250282031 -1.93197209538173 0.0544052897307063 PIK3IP1 other 1 1 1 2.84641775570863 -1.93197209538173 2.56033073820075e-11 91.3776766302697 15.4272939069611 5.92311763692001 9.54909359146281e-09 -76.8482139603801 37.4182208758513 -2.05376450727982 0.0409579151997345 NOL12 essential 2.98713787225881e-07 1 0.000118685684248291 5.92311763692001 -2.05376450727982 1.04721200242937e-26 218.756051609743 24.1438927949804 9.06051287865323 2.5757114868766e-17 -310.42388782202 68.1261186041447 -4.55660610324473 7.84774639249483e-06 SRRD other 1.61815198615387e-22 0.121027944865055 3.8676883686939e-13 9.06051287865323 -4.55660610324473 3.87149056342331e-10 244.402362830854 40.5185693477669 6.03186062008193 5.29614971525077e-09 -171.538689461926 128.841375253298 -1.33139443074622 0.184178119936098 PATZ1 other 4.28148141408984e-06 1 6.65408250224107e-05 6.03186062008193 -1.33139443074622 4.89746982675339e-08 316.135989563536 77.2121298850741 4.09438245045289 5.59193585906336e-05 -523.348229651415 187.711824269687 -2.78804082634409 0.00567822332684729 TRIOBP other 0.000478042029789398 1 0.537944229641895 4.09438245045289 -2.78804082634409 5.48305547768872e-33 375.247197930221 34.5958750990389 10.8465878332601 4.98729737768019e-23 -446.261343977429 97.6181724390897 -4.57149865467805 7.3470472739535e-06 TFIP11 essential 8.63965051619412e-29 0.113364939437103 7.74477409779956e-19 10.8465878332601 -4.57149865467805 4.4857714210814e-13 191.262736508803 27.1214075587325 7.0520947740126 1.46751352066316e-11 -77.128270467291 65.9353510541549 -1.16975596905434 0.243126940037769 GCAT other 5.59420553923061e-09 1 2.00961301519613e-07 7.0520947740126 -1.16975596905434 0.980231693140951 -0.46315073122886 3.70882243762763 -0.124878108622832 0.900711953777627 1.43197624654221 12.7231659013118 0.112548736505477 0.910471041822894 GGTLC2 other 1 1 1 -0.124878108622832 0.112548736505477 4.07086772189069e-17 1581.21879947449 206.846457672072 7.64440840452439 3.65336492220239e-13 -1283.63693584477 502.868214762887 -2.55263088451521 0.0112399650781935 EIF3L essential 5.67234708368249e-13 1 5.19983429377067e-09 7.64440840452439 -2.55263088451521 4.45896247547342e-14 640.888947333814 94.2344877324771 6.80100208273257 6.66414305710899e-11 -411.899817772532 217.977376877455 -1.88964480476384 0.0598767177305931 SNU13 other 5.74760263088524e-10 1 8.960800968495e-07 6.80100208273257 -1.88964480476384 3.37749561363664e-09 538.897895731308 141.879548801524 3.79827748455259 0.000179897358673994 -1281.62466309681 344.925971757742 -3.71565138039811 0.000246161078037762 MICALL1 other 3.53725115616165e-05 1 1 3.79827748455259 -3.71565138039811 1.23436597014089e-13 286.566892270984 37.8118604736737 7.5787567361438 5.50256491916564e-13 -33.6725958594253 91.9134714719575 -0.366351039952818 0.714387945848524 POLR2F essential 1.56912602124309e-09 1 7.79768474694963e-09 7.5787567361438 -0.366351039952818 0.616284624140317 -74.4234964228045 84.1935075813526 -0.883957665629885 0.377499722905562 -142.961134288149 204.658471185003 -0.698535142280612 0.485439387402746 SOX10 other 1 1 1 -0.883957665629885 -0.698535142280612 1.83716717485725e-11 21.271355015558 4.55110465053589 4.67388835215057 4.67813769380154e-06 -37.2981552822639 10.5277051345943 -3.5428571379437 0.000466480806923434 CCDC134 other 2.15756913015236e-07 1 0.0493262838434434 4.67388835215057 -3.5428571379437 1.24691396191239e-13 89.1765093729799 13.8415495715994 6.44266806340494 5.36369053898627e-10 -90.687923169268 36.0590346024542 -2.51498477896288 0.0124850467292585 DEPDC5 other 1.58470295419446e-09 1 6.99639793905369e-06 6.44266806340494 -2.51498477896288 1.00069362327967e-06 73.3780844372134 25.0399459352458 2.9304410092167 0.00367212870659842 -202.353232310515 60.8673661530353 -3.32449463644854 0.00100746723617203 PICK1 other 0.00890917532805888 1 1 2.9304410092167 -3.32449463644854 0.000245851153235233 102.647069882935 35.4783651492484 2.8932299854045 0.00412275232370342 -180.279015859896 99.4859383165167 -1.81210549863172 0.0710766104027123 TTC28 other 1 1 1 2.8932299854045 -1.81210549863172 0.0887335531646261 7.20474050206636 3.28289276349447 2.19463169256777 0.029035510143104 3.69571286604677 7.98009054785949 0.463116658123394 0.643651070856726 SLC16A8 other 1 1 1 2.19463169256777 0.463116658123394 4.06237342179403e-10 119.837622791035 20.7143590490564 5.78524406703736 2.00782946655931e-08 -59.4572578898416 47.4781067758753 -1.25230894674286 0.211544991840081 CENPM other 4.48729768171369e-06 1 0.000245557543760203 5.78524406703736 -1.25230894674286 0.408732143712899 43.1286057618629 33.3400370352575 1.29359801599062 0.196918107640164 11.7955859251111 76.1137913663224 0.154973043825147 0.876959218875848 SEPT3 other 1 1 1 1.29359801599062 0.154973043825147 0.0917708961575287 -9.04260590286263 18.7155242868224 -0.483160704679246 0.629373186382394 -107.439755826838 49.4085394872924 -2.17451794652767 0.0305345875088996 SLC5A1 other 1 1 1 -0.483160704679246 -2.17451794652767 0.0569485776867974 121.67202279928 50.9357757501013 2.38873406770561 0.01762866674532 88.345055910612 147.470985087661 0.59906737490156 0.549655654419502 TPTEP1 other 1 1 1 2.38873406770561 0.59906737490156 4.63331729718366e-05 161.516271324753 45.1040065462389 3.58097392432695 0.000405110660736412 -166.347857078967 110.318999264404 -1.50788040308702 0.13274147595285 KDELR3 other 0.355885101596677 1 1 3.58097392432695 -1.50788040308702 0.47767623405721 7.00144273970561 5.91505390854387 1.18366507693067 0.237590602125847 2.33787412849162 13.5006682002185 0.173167290227441 0.862650162495192 CYP2D6 other 1 1 1 1.18366507693067 0.173167290227441 0.001881460074748 496.941917270429 323.222717372848 1.53745974698056 0.125338947229044 -2032.91325207168 790.564064049149 -2.57147186991956 0.0106564642329242 DDX17 other 1 1 1 1.53745974698056 -2.57147186991956 0.23592869367202 5.44804066192471 3.30147155307372 1.65018555342466 0.100054986051585 1.04687659748492 8.10416606281603 0.12917758463616 0.897312251218643 DMC1 other 1 1 1 1.65018555342466 0.12917758463616 3.71071888132577e-12 384.844100470059 83.0232729280174 4.63537616499081 5.56128185173674e-06 -741.850287073794 189.494411720971 -3.91489268911087 0.000114685182982976 TCF20 other 4.47512697087888e-08 1 0.058304478933608 4.63537616499081 -3.91489268911087 4.02460191776357e-12 63.2326189025079 10.8592466569387 5.82292868926634 1.63248198444547e-08 -74.771160722703 28.3019098140692 -2.64191219652369 0.00872311393593032 HSCB essential 4.84360840802846e-08 1 0.000200664685528037 5.82292868926634 -2.64191219652369 7.20901238643184e-12 122.290665576117 20.3290034360117 6.01557601980063 5.74213909438200e-09 -115.957195924071 49.9018746908822 -2.32370420234448 0.0208758335283629 CBY1 other 8.59386366586539e-08 1 7.20236506608334e-05 6.01557601980063 -2.32370420234448 1.40837369691974e-14 800.534914630406 102.659046337595 7.79799679804 1.33402972023863e-13 -159.899243431142 251.998524293091 -0.634524523029225 0.526269936877906 TOMM22 essential 1.8390543734378e-10 1 1.91046396235375e-09 7.79799679804 -0.634524523029225 6.94839941234433e-13 18.5848013151028 2.48274496471648 7.48558614727675 9.93148018902937e-13 -1.72011443141607 8.42546241310227 -0.204156679726107 0.838383732233541 RSPH14 other 8.61879463107191e-09 1 1.39924624383235e-08 7.48558614727675 -0.204156679726107 0.906418515143198 -111.435101456478 336.369287356799 -0.331287979149756 0.74068394809812 -342.784092735165 879.574225960644 -0.38971593598117 0.697053840605894 XBP1 other 1 1 1 -0.331287979149756 -0.38971593598117 1.9055780988377e-15 498.996961926529 79.6270006012295 6.26668037423005 1.4450416488322e-09 -734.451673742619 208.115021120678 -3.52906613750258 0.000489763261927864 RTCB essential 2.54890126500531e-11 1 1.85687851874938e-05 6.26668037423005 -3.52906613750258 4.97876244976292e-18 483.411358756773 73.4687729789135 6.57982077495044 2.39675633534394e-10 -815.747870020107 180.344772650886 -4.52326872594885 9.09021849336696e-06 JOSD1 other 7.05888940127387e-14 0.139962094142371 3.163718362654e-06 6.57982077495044 -4.52326872594885 8.19427783668859e-23 418.79521690016 50.505855033806 8.29201320559448 5.2463170821197e-15 -516.932644125398 129.901823149223 -3.97941023146057 8.87523239746393e-05 FBXO7 other 1.23520544110244e-18 1 7.67641115455754e-11 8.29201320559448 -3.97941023146057 4.54640845464625e-14 262.840529013978 58.7948674432034 4.4704672438948 1.14530321830433e-05 -747.823322427836 144.324541872052 -5.18153955472663 4.28329497517602e-07 GTPBP1 other 5.85895657550262e-10 0.00673505301896678 0.117084348007252 4.4704672438948 -5.18153955472663 9.16160186307365e-22 412.253169485876 56.5890199568061 7.28503815405437 3.51253545366719e-12 -611.155013067923 129.147046279402 -4.7322415082241 3.58014087482516e-06 POLDIP3 other 1.36773554213827e-17 0.0555602062364117 4.88839559086862e-08 7.28503815405437 -4.7322415082241 3.31184010196848e-13 138.225676358496 18.2509777533585 7.57360390366266 5.68590557315277e-13 -16.9359708183322 61.9366585165335 -0.273440176205361 0.784722383738829 RAB36 other 4.1500668317767e-09 1 8.05294806325626e-09 7.57360390366266 -0.273440176205361 0.54069886522499 767.5023323001 963.464291337557 0.79660693105148 0.426374101321986 -1045.61841463782 2422.82458065253 -0.431570004278314 0.666395833669634 TIMP3 other 1 1 1 0.79660693105148 -0.431570004278314 1.33709960169886e-18 282.457206362883 44.4804319862532 6.35014530547225 9.34935997850466e-10 -387.232824479956 94.4567689017873 -4.09957728791874 5.51424046209844e-05 PPP6R2 other 1.91379065991157e-14 0.830885752828993 1.20943320681936e-05 6.35014530547225 -4.09957728791874 4.9622590727982e-12 540.867059790869 107.655732534703 5.02404328182448 9.35418848724518e-07 -662.218519166002 227.182235547662 -2.91492210017923 0.0038641754313042 SBF1 other 5.94627504693408e-08 1 0.0103981159224217 5.02404328182448 -2.91492210017923 7.25981977912176e-09 612.412592927979 166.728576763078 3.67311114157845 0.000288294485733368 -1517.23670892547 409.270851431983 -3.70717021165046 0.000253787618908927 SUN2 other 7.4587388410697e-05 1 1 3.67311114157845 -3.70717021165046 3.71415143393367e-20 1195.05693706414 174.365978505043 6.8537277014138 4.87185598577239e-11 -1840.33832927661 398.045857531066 -4.62343293984155 5.85723066527749e-06 CYB5R3 other 5.43826052956568e-16 0.0905059282398678 6.57554402399699e-07 6.8537277014138 -4.62343293984155 6.4604322352372e-11 125.805599777995 22.030489044408 5.71052233676711 2.93656475008838e-08 -121.2555720274 54.0785340084817 -2.2422126311409 0.025750669058408 DNAL4 other 7.41334598993469e-07 1 0.000356293401128223 5.71052233676711 -2.2422126311409 6.51487317583179e-13 462.258554245568 92.2805791683392 5.00927235623772 1.00336462889524e-06 -645.080686837094 194.736571657606 -3.3125811004381 0.00105406696378464 LMF2 other 8.08951802243033e-09 1 0.0111273137344482 5.00927235623772 -3.3125811004381 4.40026792137982e-10 126.20376140888 27.7996816591502 4.53975563304123 8.49027000401523e-06 -235.961340155846 72.9175178032009 -3.23600346342958 0.00136329040986846 RHBDD3 other 4.84821519577629e-06 1 0.0876875086014693 4.53975563304123 -3.23600346342958 3.56190450648421e-14 322.310491138954 64.2270674757151 5.01829686153463 9.4505991755214e-07 -634.625903711194 146.037550943358 -4.34563507544263 1.96578817859302e-05 PACSIN2 other 4.60447395553214e-10 0.300254486398297 0.0105015058038394 5.01829686153463 -4.34563507544263 3.22149550012018e-05 30.0954285241437 8.54736610513184 3.52101783800677 0.000503907274819916 -29.3382525031407 19.3525867812285 -1.51598609709365 0.130684128309255 TTLL1 other 0.251631013514387 1 1 3.52101783800677 -1.51598609709365 5.51358140338334e-19 950.563378405578 128.773273422302 7.38168218562151 1.92402672807916e-12 -1252.62725706573 337.784972891945 -3.70835696550194 0.000253004719571418 AP1B1 other 7.94617351855607e-15 1 2.6932526139652e-08 7.38168218562151 -3.70835696550194 3.88966610739301e-13 147.901049970515 30.6442032076312 4.8263956797442 2.32903728034095e-06 -299.736423548169 71.930655035254 -4.16701924097959 4.15866412756196e-05 HMGXB4 other 4.86286056746275e-09 0.629413815706502 0.0251489445531215 4.8263956797442 -4.16701924097959 6.14493198083132e-06 158.631388276147 50.1197931171392 3.16504475398365 0.00172811831048121 -290.52289678293 117.645400166563 -2.46947943881875 0.0141499182307338 TOM1 other 0.0511688486043824 1 1 3.16504475398365 -2.46947943881875 0.219354607252977 144.205596404745 83.530287096559 1.72638693601097 0.085417481296557 74.8963660666243 219.108165947119 0.341823709503828 0.732748484170147 NEFH other 1 1 1 1.72638693601097 0.341823709503828 0.00272906319538063 28.8563258129065 46.9825396457169 0.61419254962598 0.539623088386423 -279.446877406077 99.3029964169016 -2.81408303363658 0.00526407248088853 CHKB other 1 1 1 0.61419254962598 -2.81408303363658 0.0415531470847133 25.9499185153038 21.0091720500246 1.23517092694157 0.217832736712926 -75.9574593074737 47.4991844491723 -1.59913186275343 0.110952213700662 BIK other 1 1 1 1.23517092694157 -1.59913186275343 0.983245932032358 -125.861454943544 734.063944845537 -0.171458434687223 0.863991741340628 -213.702848242952 1723.05672406431 -0.124025428332315 0.901387422593104 HMOX1 other 1 1 1 -0.171458434687223 -0.124025428332315 9.23897501177042e-14 68.4550418339662 11.4828585361454 5.96149831668528 7.73249492683538e-09 -78.1050853648488 25.9613474683067 -3.00851430998328 0.00287127138455542 MCAT other 1.17926277050238e-09 1 9.64474092224176e-05 5.96149831668528 -3.00851430998328 3.9804454475119e-22 360.102081532614 41.1857936021802 8.7433566294945 2.42890897077213e-16 -337.162467291047 108.034391032543 -3.12088089791225 0.00199800670583079 THOC5 essential 5.96469750309658e-18 1 3.614459439406e-12 8.7433566294945 -3.12088089791225 1.40878712147028e-10 570.350228682787 119.343851730323 4.7790499503199 2.89093302952543e-06 -868.324211872944 283.48874852688 -3.06299356283133 0.00241192828959044 MCM5 essential 1.59023890271565e-06 1 0.0310081476746898 4.7790499503199 -3.06299356283133 0.537448589329884 -2.97127872127872 2.81815650126371 -1.05433417907996 0.292662158434727 0.0739029489029519 7.08736461095199 0.0104274230210692 0.991687886778585 APOBEC3H other 1 1 1 -1.05433417907996 0.0104274230210692 0.0011130133387655 64.7752185957038 55.5842630955628 1.16535175584391 0.244944637804288 -311.924758376398 115.857696198393 -2.69230934682373 0.00755673225217221 ARSA other 1 1 1 1.16535175584391 -2.69230934682373 4.45728912342572e-07 399.497226783851 145.452609468067 2.74657999086333 0.00642397788058247 -1139.67593302877 328.850670996769 -3.46563359464749 0.000614513367870652 TSPO other 0.00408688839726904 1 1 2.74657999086333 -3.46563359464749 0.24731748802754 19.0919762169903 57.5673399751585 0.331645968447194 0.740412935365054 -192.794681965213 136.745152171359 -1.40988312129426 0.159720820730512 RASD2 other 1 1 1 0.331645968447194 -1.40988312129426 6.06335058116426e-11 663.756981969856 170.328828421868 3.8969150913542 0.000122737345397454 -1593.71005041373 385.092778475878 -4.13850931383684 4.66576225274651e-05 TTLL12 other 6.96618348269961e-07 0.705089991635052 1 3.8969150913542 -4.13850931383684 0.360155619463152 20.7077922077921 48.5358529693461 0.426649392993476 0.669970962304777 -141.599506974507 122.062520851152 -1.16005720664396 0.247039021606767 CBX7 other 1 1 1 0.426649392993476 -1.16005720664396 0.0391676550444397 62.484272608126 48.6016440336224 1.28564113108807 0.199657805873147 -198.425143196932 120.143445610517 -1.65156860774736 0.0997722721822598 PDGFB other 1 1 1 1.28564113108807 -1.65156860774736 0.334176575824113 13.2278881561031 16.3274179371911 0.810164118232817 0.418556695350487 61.8982233562642 42.8284245537737 1.44526033822578 0.149540115693612 CABP7 other 1 1 1 0.810164118232817 1.44526033822578 1.18481037112543e-05 3428.10550458717 826.78083345573 4.14632919132701 4.51386770020342e-05 -2035.32041284404 2043.80530887779 -0.995848481263406 0.320205616094259 RPL3 essential 0.0964198680021878 1 0.438070860304742 4.14632919132701 -0.995848481263406 1.03821267092819e-05 54.8055992990516 14.2366836793178 3.84960434140079 0.00014764768936669 -56.7359543909919 37.344222779202 -1.51926992098466 0.129860348571661 ZMAT5 essential 0.0849050322285077 1 1 3.84960434140079 -1.51926992098466 1.20583062089049e-15 414.758137827508 74.5074144555251 5.56666931550933 6.24135132023795e-08 -759.707128997793 176.621394446664 -4.30133128196544 2.372130779596e-05 RBFOX2 other 1.62075693753891e-11 0.361560173426022 0.00074571665574203 5.56666931550933 -4.30133128196544 0.000182712943418077 75.5649160223939 36.8917569650445 2.04828726628533 0.0414917691797197 -255.242094700672 91.7615587236339 -2.78157976227721 0.00578781295880409 SYNGR1 other 1 1 1 2.04828726628533 -2.78157976227721 6.45050080484309e-18 145.967564205101 20.3143416354428 7.18544399934816 6.44866416624869e-12 -179.889017249721 50.5282427909 -3.56016768669657 0.000437298169692787 TAB1 other 9.12874873901395e-14 1 8.91076414492244e-08 7.18544399934816 -3.56016768669657 7.12521282508855e-17 475.35834693301 71.882740814709 6.61296914315404 1.9986552307479e-10 -719.590220785538 189.17098592068 -3.8039143121412 0.000176054416158504 ASCC2 other 9.87126984787768e-13 1 2.64661925655637e-06 6.61296914315404 -3.8039143121412 1.19204876445217e-14 262.211916365352 52.4498196554181 4.99929109552743 1.03231742617965e-06 -656.130797044489 138.037702981025 -4.75327235150155 3.24734894669944e-06 MTMR3 other 1.56063024242079e-10 0.0504410711890824 0.0114391093994967 4.99929109552743 -4.75327235150155 2.38549795920732e-24 354.310161734648 42.3516221925358 8.36591713356124 3.15200077073474e-15 -495.977159177305 105.341983862244 -4.70825724932138 3.98562845135461e-06 MIEF1 other 3.63907713677077e-20 0.0618091260236074 4.62381274477015e-11 8.36591713356124 -4.70825724932138 0.405080860005182 38.9192264066111 51.6146236213112 0.754034877637696 0.45148054103308 -92.194772265116 122.358991862579 -0.753477704104162 0.451814609166863 APOL4 other 1 1 1 0.754034877637696 -0.753477704104162 0.0519840522146719 -1614.97587465627 737.026761645793 -2.19120384590921 0.0292884817972764 -3198.91524479913 1757.26043080262 -1.82039906477496 0.0698011656899862 APOL1 other 1 1 1 -2.19120384590921 -1.82039906477496 6.47775907693658e-10 27.3956091100249 6.85330124115589 3.99743249946566 8.24612924555703e-05 -55.4087047707472 15.9615542967775 -3.47138528870799 0.000601725795734215 PNPLA3 other 7.07630401564552e-06 1 0.780496133091973 3.99743249946566 -3.47138528870799 1.35122305245194e-11 6523.20573433189 1630.42847517437 4.00091499483548 8.13966023378845e-05 -16566.7433822134 3877.71963788114 -4.27229014196235 2.67776651610234e-05 MYH9 other 1.59633491416672e-07 0.407556063750776 0.77107001394678 4.00091499483548 -4.27229014196235 0.335297228206524 9.54021835937937 7.56269584724399 1.26148380843004 0.208219350092839 -5.74480373244359 18.812395318637 -0.305373326210742 0.760316255863285 CACNA1I other 1 1 1 1.26148380843004 -0.305373326210742 8.61308025886659e-24 328.244076572272 36.6401596646362 8.95858750553103 5.27204964385395e-17 -255.904149212157 85.3360850997772 -2.99878004613109 0.00296058785678057 SAMM50 essential 1.30867141453219e-19 1 7.89014949699182e-13 8.95858750553103 -2.99878004613109 1.17949632241671e-15 346.353118259725 51.1686060209564 6.76885975978854 7.91535110499307e-11 -333.045925174071 120.570773699387 -2.76224424008788 0.00613036851292352 TXN2 other 1.58571485585702e-11 1 1.06121112264642e-06 6.76885975978854 -2.76224424008788 1.80037850768084e-06 260.731574181939 80.6830747418931 3.23155228052507 0.00138215550975161 -506.218532893498 190.116978017563 -2.66266873254599 0.00821255507397819 FOXRED2 other 0.0157209051290691 1 1 3.23155228052507 -2.66266873254599 0.26548889477344 -9.3291832866784 6.66655754481821 -1.3994003987755 0.162840760836612 5.44904562143638 16.6302686933871 0.327658303176013 0.743423951778859 GRAP2 other 1 1 1 -1.3994003987755 0.327658303176013 6.88717216115044e-22 1470.29949884081 175.115980154669 8.39614692812269 2.53770335258282e-15 -1326.40323385763 412.63326981641 -3.21448446085739 0.0014637802944836 EIF3D essential 1.02967342160022e-17 1 3.72813999527943e-11 8.39614692812269 -3.21448446085739 1.11831024697489e-13 216.437002161921 41.6054201779327 5.20213475158504 3.90978734673064e-07 -434.869626130275 103.793424221903 -4.18976085807279 3.79016103258483e-05 TNRC6B other 1.42349711337434e-09 0.574285199657254 0.00445637561780359 5.20213475158504 -4.18976085807279 6.76023428882668e-06 148.378643071682 52.6794009978385 2.81663497042744 0.00521110723873437 -387.160626690228 131.872858551764 -2.93586285261464 0.00361266706027515 SGSM3 other 0.0561234650658391 1 1 2.81663497042744 -2.93586285261464 7.45271858463511e-11 157.083054591171 29.0875365739613 5.40035606630881 1.44729099921412e-07 -158.646846176619 68.5402058499576 -2.3146537745147 0.0213740193482096 IFT27 other 8.52963642011488e-07 1 0.00169521194737949 5.40035606630881 -2.3146537745147 0.0390724239772539 25.8610912467271 12.2866555074461 2.10481129149056 0.0362216857123253 -16.5702350148855 28.9515715965349 -0.572343195934438 0.56756050803209 PVALB other 1 1 1 2.10481129149056 -0.572343195934438 2.92546223829815e-11 693.747643736606 168.673167464767 4.11296979931035 5.17414756565251e-05 -1468.75839674209 376.787314991841 -3.89810999017812 0.000122065626890211 KIAA0930 other 3.4058231378267e-07 1 0.498994791231528 4.11296979931035 -3.89810999017812 0.0129324804379923 -52.6201859306335 21.023450788437 -2.50292810919389 0.0129017002601366 27.6092669273387 49.5384557936694 0.557329987077775 0.577758653533612 NCF4 other 1 1 1 -2.50292810919389 0.557329987077775 0.956312416769906 -16.3551684563836 127.804413533263 -0.127970294641873 0.89826669680718 61.1791604029781 301.151002933145 0.203151109599857 0.839168257470993 CSF2RB other 1 1 1 -0.127970294641873 0.203151109599857 3.40176618679264e-18 151.66108635516 20.8433292457579 7.27624097700353 3.73859609643528e-12 -169.463346513291 51.6479014626673 -3.28112743623832 0.00116993274146518 SLC25A17 other 4.83595081114441e-14 1 5.20001331053184e-08 7.27624097700353 -3.28112743623832 1.91575450442131e-05 119.944230559692 37.025337683054 3.23951753219494 0.00134552548014797 -158.539779537282 82.7083393402108 -1.91685361841383 0.0563003247211749 FAM118A other 0.15314541508344 1 1 3.23951753219494 -1.91685361841383 0.0327629642359098 32.6409877853262 17.3072744184935 1.88596927488756 0.0603605931928454 -40.8418705329166 40.7818705557609 -1.00147124142022 0.31748586547666 KCTD17 other 1 1 1 1.88596927488756 -1.00147124142022 4.94339766871332e-20 953.953260606711 111.046635497811 8.59056428256678 7.0391270364062e-16 -534.23807476614 264.068695693129 -2.02310263760674 0.0440478809140716 ST13 other 7.22873041095948e-16 1 1.04101649741411e-11 8.59056428256678 -2.02310263760674 0.0432918655419893 -110.737185959996 44.6314639204731 -2.48114617430685 0.0136985362903195 -52.4474123214008 105.416843340387 -0.49752402613736 0.619220048862864 IL2RB other 1 1 1 -2.48114617430685 -0.49752402613736 0.000151368527070804 222.444847748809 64.9879954949031 3.42286057686231 0.000715802319075774 -166.688887610965 153.392682020902 -1.08668083388914 0.278147064296771 RBX1 essential 1 1 1 3.42286057686231 -1.08668083388914 2.22652306324754e-18 172.511559176624 25.4308053492992 6.78356649768379 7.34377349542017e-11 -237.360895567926 60.0233098502406 -3.95447862105816 9.79684270368772e-05 L3MBTL2 other 3.17568984510996e-14 1 9.85167214410616e-07 6.78356649768379 -3.95447862105816 0.00766985637885921 -3.7130668081882 7.36431698546177 -0.504197037623223 0.614532589204863 -53.4091655699173 17.3817020020541 -3.07272357814014 0.00233724824645782 CHADL other 1 1 1 -0.504197037623223 -3.07272357814014 1.6823485546701e-11 799.974403476645 168.43699646426 4.74939841168675 3.31653032449183e-06 -1377.20195502696 397.608921790127 -3.46370989067972 0.000619402656315422 RANGAP1 essential 1.97844190029204e-07 1 0.0353774289713544 4.74939841168675 -3.46370989067972 5.59327649805801e-10 533.819772050182 127.914261197634 4.17326236380637 4.0530271254315e-05 -1030.21143927 301.951783420476 -3.41184088267299 0.000744112182953063 ZC3H7B other 6.12743440362255e-06 1 0.3949674933733 4.17326236380637 -3.41184088267299 7.78918771576768e-10 278.002213901112 43.5402773509444 6.38494356984344 7.45105123237198e-10 40.6162395698706 102.780286370313 0.39517538824062 0.693025477305743 PHF5A essential 8.47385731598366e-06 1 9.67146449961883e-06 6.38494356984344 0.39517538824062 7.13320139707627e-25 871.97760991509 104.698208646721 8.32848642957559 4.15812401826243e-15 -1117.43950971792 245.769249035132 -4.54670189254712 8.23426320739763e-06 ACO2 essential 1.09145114576664e-20 0.12691469881562 6.09289912395994e-11 8.32848642957559 -4.54670189254712 8.62811949521572e-24 607.010311322622 72.3504449146924 8.38986286868507 2.75068839031065e-15 -673.083146478746 169.510178139624 -3.97075357872807 9.19362813656262e-05 POLR3H essential 1.31078391371317e-19 1 4.03966097001023e-11 8.38986286868507 -3.97075357872807 5.661485868761e-08 126.843075204987 30.600931976785 4.14507229064837 4.55601095786315e-05 -154.008313379157 67.0079249675068 -2.29835968587056 0.0223085187648849 TRMU other 0.00055052288587832 1 0.441796382583989 4.14507229064837 -2.29835968587056 3.93272723190777e-10 129.167663097037 26.7824047271442 4.82285531911645 2.36742637495852e-06 -170.86900183451 62.7570692905934 -2.72270524685131 0.00689668209472102 PMM1 other 4.34802322759723e-06 1 0.0255421631594275 4.82285531911645 -2.72270524685131 9.33036678004761e-18 276.355167203206 40.8967621246343 6.75738500669086 8.6250126608415e-11 -357.543757864892 95.8301153523887 -3.73101666996981 0.00023247684697904 DESI1 other 1.31632814532912e-13 1 1.15497544541329e-06 6.75738500669086 -3.73101666996981 8.98726149244277e-09 269.217083740725 61.030069476342 4.41122033860842 1.49018748478418e-05 -325.746151269634 134.640832876412 -2.41937118413875 0.0162134329257652 CERK other 9.18587997142575e-05 1 0.15086658095955 4.41122033860842 -2.41937118413875 4.53227287848031e-15 242.081630332293 45.1162270375073 5.36573304613966 1.74519232588991e-07 -391.238118872869 98.8647920254768 -3.95730482872051 9.71365703332927e-05 BRD1 other 6.00934060957704e-11 1 0.00203402165582469 5.36573304613966 -3.95730482872051 1.56372561424205e-13 227.809899141702 40.5831584243708 5.61340979821076 4.98133515042103e-08 -266.320377901936 87.8067924789662 -3.0330270629773 0.00266046780854965 ZBED4 other 1.98077123556041e-09 1 0.000598607045026095 5.61340979821076 -3.0330270629773 0.500154613811857 8.9746728153668 15.5051458779806 0.57881898603173 0.563199273724691 -22.6204156274662 33.1024037196763 -0.683346617938217 0.494980394065497 MLC1 other 1 1 1 0.57881898603173 -0.683346617938217 7.40581206375716e-09 183.302894049614 38.9382629429897 4.70752622729964 4.03901683853113e-06 -151.860317632853 83.0387000381037 -1.82878967954905 0.0685507478630447 HDAC10 other 7.6057689894786e-05 1 0.0428458906231382 4.70752622729964 -1.82878967954905 0.00937033484427955 25.0158906417421 10.7317948792365 2.3310071542778 0.0204894251370672 -15.9426770031566 21.4077022141396 -0.744716870763766 0.457090601520423 KCNK10 other 1 1 1 2.3310071542778 -0.744716870763766 1.61448927751433e-07 533.506378366851 133.049165607056 4.00984384932179 7.85451018588495e-05 -326.219518595258 252.800817190552 -1.29042113953835 0.198000342836027 ABHD4 other 0.00152375498011802 1 0.745078836233046 4.00984384932179 -1.29042113953835 1.66078703084597e-14 452.710384731673 88.0147587976081 5.14357354284968 5.17594639389828e-07 -515.58017144782 173.025153609824 -2.97979895229838 0.00314603426308302 KHNYN other 2.16473426751414e-10 1 0.00584623145190811 5.14357354284968 -2.97979895229838 5.18358049534018e-16 430.574901648763 71.9916941601368 5.98089691695547 7.40052005820348e-09 -326.744204521456 130.632304612151 -2.5012511682433 0.0129983704494867 FKBP3 other 7.03152694192895e-12 1 9.23954929266705e-05 5.98089691695547 -2.5012511682433 2.14138054520494e-12 244.016614241126 50.7557895314118 4.80766069238483 2.53472362172031e-06 -257.031303513523 99.7790416088613 -2.57600493419348 0.0105250273962167 SDR39U1 other 2.60670253767798e-08 1 0.0272939039586843 4.80766069238483 -2.57600493419348 0.191848777062866 -4.81313903518692 7.19323315424942 -0.669120398571196 0.503990405314114 15.5053862806553 14.0896207653378 1.10048286883635 0.272101950204862 CTSG other 1 1 1 -0.669120398571196 1.10048286883635 0.564910064256255 -14.1186384051181 13.2150014812823 -1.06837963091535 0.286303565574002 -13.1337619955411 25.8846551045896 -0.507395672937221 0.612291409615608 GZMH other 1 1 1 -1.06837963091535 -0.507395672937221 0.3870644251144 -12.4883408187665 33.2927017627347 -0.375107460721168 0.707875035283334 61.2762060163492 65.2115025373972 0.939653337709997 0.348235268547067 GZMB other 1 1 1 -0.375107460721168 0.939653337709997 3.28332777964716e-11 183.354957074088 53.4782294223744 3.42859064435248 0.000700754390057066 -356.71541566328 101.087170204883 -3.52879020097498 0.000489970203323863 RBM23 other 3.8142418816161e-07 1 1 3.42859064435248 -3.52879020097498 1.31923202155746e-22 549.416539814995 74.2565646485973 7.39889520091573 1.71333251224403e-12 -404.46420665257 140.363397788972 -2.88155041145882 0.00427268927550021 PRMT5 essential 1.98465265323104e-18 1 2.40140684916124e-08 7.39889520091573 -2.88155041145882 0.0469203772304112 98.036113318049 97.144223842078 1.00918108602546 0.313804904570065 -248.967169091776 175.438503864122 -1.41911361307893 0.157036605644799 COCH other 1 1 1 1.00918108602546 -1.41911361307893 3.94780055881209e-17 68.7486562000154 10.1641369236342 6.76384593365299 8.56311279652551e-11 -37.0161931044582 18.3423635743035 -2.01807106017218 0.0445914526805797 AP4S1 other 5.50323397898405e-13 1 1.1467720657107e-06 6.76384593365299 -2.01807106017218 3.2446609902875e-16 77.9361329002579 13.1738319644337 5.91598049152799 1.0153767296934e-08 -64.1726084160624 24.0405643499311 -2.66934700375477 0.00806908594927082 POLE2 other 4.42474419245506e-12 1 0.000126038713456841 5.91598049152799 -2.66934700375477 3.36674863506342e-17 59.9462531904164 8.08450772261601 7.41495403891071 1.58854705101809e-12 -18.9258054894965 14.9779038609171 -1.26358171779169 0.207474170539973 VCPKMT other 4.69998109454854e-13 1 2.22793723905288e-08 7.41495403891071 -1.26358171779169 1.53540558549305e-14 147.707025053514 29.3349268685512 5.03519322599248 8.75617980666302e-07 -184.833864079669 54.3478625389969 -3.40094081799524 0.000773534753367331 SOS2 other 2.00324366739278e-10 1 0.0097491305967386 5.03519322599248 -3.40094081799524 3.3847553392374e-05 15.2628299623352 5.92475509021237 2.57611154046675 0.0105258442096494 -22.4902347513257 10.9766005779713 -2.04892531085269 0.0414395845243513 CDKL1 other 0.263706288479986 1 1 2.57611154046675 -2.04892531085269 5.21376258400573e-12 285.364106107106 49.8511036687395 5.72432875314758 2.75848524992283e-08 -167.756650210391 95.4321538977569 -1.75786297760942 0.0799039552941672 NIN other 6.24556619938047e-08 1 0.000335266297275621 5.72432875314758 -1.75786297760942 1.11460310562335e-10 1059.87966434751 186.558979392344 5.68120423792909 3.45740336676304e-08 -397.825006249221 357.138035512399 -1.11392505611576 0.266301969983996 PYGL other 1.26496306457194e-06 1 0.00041817293720999 5.68120423792909 -1.11392505611576 0.000172000541315029 62.555718729603 16.2590494123022 3.84744010201919 0.000149006887082034 6.5266372953379 31.1254113059698 0.209688387124578 0.834069022618281 TRIM9 other 1 1 1 3.84744010201919 0.209688387124578 8.98249284465293e-17 391.380175611187 48.5528399748329 8.06091210759364 2.49638478340687e-14 -35.3577904705975 92.5428446575105 -0.382069414458268 0.702711538850481 PSMC6 essential 1.24120086127414e-12 1 3.61601335876486e-10 8.06091210759364 -0.382069414458268 2.12788586722452e-15 322.977867997944 44.0072304135512 7.3392000578725 2.54930937563963e-12 -82.5226106746939 83.8788068850252 -0.983831479479789 0.326082425244854 GNPNAT1 other 2.84306830719868e-11 1 3.55960068120562e-08 7.3392000578725 -0.983831479479789 3.08245425195197e-05 98.4457663901323 25.8031925150757 3.8152552763622 0.000168816365644673 -32.3325312385289 49.1814863523585 -0.657412649281967 0.511477734557546 DDHD1 other 0.241171220672722 1 1 3.8152552763622 -0.657412649281967 6.56348566423542e-13 185.964186510596 26.262852688582 7.08088297625966 1.24063137579504e-11 8.89431847190145 50.5666976626961 0.175892808568018 0.86051000286077 CDKN3 other 8.14856745214828e-09 1 1.70264250014111e-07 7.08088297625966 0.175892808568018 2.52020253645756e-09 668.076092518616 126.410143745481 5.28498799798649 2.5946281632686e-07 -232.880644431833 243.391058696938 -0.956816760971517 0.339515681486655 CNIH1 other 2.66284600002105e-05 1 0.00299446036322829 5.28498799798649 -0.956816760971517 1.77290760278469e-05 55.1049861079003 15.3116042764839 3.59890349259696 0.000379832293763629 -32.4620231671451 29.4761849558668 -1.101296630339 0.271744762389231 CGRRF1 other 0.142187189743332 1 1 3.59890349259696 -1.101296630339 2.91326522562958e-16 257.415601231307 41.937750807098 6.13804022097768 2.95657092216759e-09 -207.230184155238 76.1859171026322 -2.72005892999978 0.00694902194437764 ATP6V1D essential 3.9771896860295e-12 1 3.75336678569176e-05 6.13804022097768 -2.72005892999978 7.71448388605871e-07 420.641299101218 81.8411341564204 5.13972959242304 5.2614792098362e-07 146.32291883808 148.483150508443 0.985451334626414 0.325278189922197 PLEK2 other 0.00693069232323515 1 0.00594073617582605 5.13972959242304 0.985451334626414 1.51989123729118e-15 88.4964371322081 13.3193630771176 6.64419436723992 1.66614213647473e-10 -42.1055997725042 24.150169127628 -1.74349088612945 0.0823819478004529 PIGH other 2.03817414920747e-11 1 2.21296998566574e-06 6.64419436723992 -1.74349088612945 9.58101994327637e-16 590.320367205987 82.1525181231506 7.18566369835515 6.43995519615965e-12 -138.022372565345 152.312106802932 -0.906181231830275 0.365641964022101 PSMA3 essential 1.29132986795479e-11 1 8.89937408557302e-08 7.18566369835515 -0.906181231830275 1.97506975069864e-28 550.174193554772 58.2703600445261 9.44175037076084 1.76976537911533e-18 -295.824071196655 105.653629385679 -2.79994234856595 0.00547878343247725 VTI1B other 3.07399855998737e-24 1 2.68349524435258e-14 9.44175037076084 -2.79994234856595 3.50026503452038e-18 171.167083946197 21.7527264192787 7.86876461584593 8.50969351302279e-14 -37.2223930666806 40.3299091168635 -0.922947605927445 0.356852484379591 TIMM9 essential 4.97457666706036e-14 1 1.2220770854052e-09 7.86876461584593 -0.922947605927445 2.81047189562566e-18 166.659784784785 24.4180536520145 6.82526900628033 5.66387253323922e-11 -138.877551464508 46.0126501233419 -3.0182471796828 0.00278265357705089 GSTZ1 other 4.00295512093962e-14 1 7.63036907677988e-07 6.82526900628033 -3.0182471796828 1.89049309596494e-17 81.1929562441555 13.0829569044682 6.20600960753956 2.01908208567096e-09 -73.7594439109583 24.2560152123928 -3.0408722646774 0.00258908630627892 KIAA0586 other 2.65141656709082e-13 1 2.57917545623609e-05 6.20600960753956 -3.0408722646774 1.44350914069047e-14 133.960895105632 23.2816054626515 5.75393717243999 2.33673168130017e-08 -127.664671536525 43.8711611387703 -2.90999071423491 0.00391215153674912 TMED8 other 1.88421248134327e-10 1 0.000284847591950491 5.75393717243999 -2.90999071423491 9.2935949601788e-05 10.7180733364944 3.13167050528384 3.42247797730016 0.00071566370151593 -5.16781770328677 5.90122625311401 -0.875719296571585 0.381952496979166 SAMD15 other 0.691629336936506 1 1 3.42247797730016 -0.875719296571585 2.10804575513364e-15 735.166732521997 96.7149130146928 7.60137924551833 4.72163900984474e-13 -73.2069827264334 182.246689997233 -0.401691700011367 0.688225208670396 AHSA1 other 2.81698154258509e-11 1 6.70189441057362e-09 7.60137924551833 -0.401691700011367 4.14886872341703e-12 235.367069633944 55.444030832615 4.24512911668553 3.00069071917896e-05 -342.475251890813 102.794136305148 -3.33166135930323 0.000982878415491718 DAAM1 other 4.990259300526e-08 1 0.296198180890155 4.24512911668553 -3.33166135930323 0.000227984441712521 26.0924740530004 7.04124456988119 3.70566222974423 0.000255229207975877 0.131667136243799 13.2683107115745 0.00992342876994437 0.992089627050522 ISM2 other 1 1 1 3.70566222974423 0.00992342876994437 1.0905326658638e-08 337.952887097624 84.0203742110752 4.02227305306475 7.46649973491091e-05 -386.144847364528 158.325480683327 -2.4389305227304 0.015368231836346 SPTLC2 other 0.000110885361465031 1 0.710213454784726 4.02227305306475 -2.4389305227304 0.0898284804541422 -79.3024557144483 36.7374300007066 -2.15862829035463 0.0317537957895498 -105.727542388954 79.3411122166041 -1.33256945151354 0.183788382629305 RIN3 other 1 1 1 -2.15862829035463 -1.33256945151354 2.92982756845154e-05 176.6281570722 120.602892717841 1.46454328823964 0.144200388439413 -879.891381147982 261.443982821327 -3.36550633773547 0.000874126849846858 LGMN other 0.229698481366601 1 1 1.46454328823964 -3.36550633773547 2.78223509923956e-29 86.3175346399031 8.36329058184473 10.3210014999698 2.66434112219346e-21 -36.5941192909157 15.7595346830813 -2.3220304423202 0.0209671922600174 ALKBH1 other 4.34668589554196e-25 1 4.10335176229014e-17 10.3210014999698 -2.3220304423202 1.25126439647382e-26 395.611012328118 41.6869950693441 9.49003428215538 1.20377882934729e-18 -199.293390644649 78.5537269331439 -2.53703291270019 0.0117367253335705 SNW1 essential 1.93232760747452e-22 1 1.82793815236387e-14 9.49003428215538 -2.53703291270019 0.59186977159062 -436.271530962917 679.226345346814 -0.64230655060966 0.521215151044064 -1359.02860589948 1357.31419980342 -1.00126308712921 0.317589535001586 CHGA other 1 1 1 -0.64230655060966 -1.00126308712921 7.8908406504441e-11 284.998908001737 61.4312153449738 4.63931742846523 5.4384542997974e-06 -341.149399141941 122.759462247213 -2.77900695308468 0.00583255526391652 ITPK1 other 9.02080903158769e-07 1 0.0570711394220739 4.63931742846523 -2.77900695308468 4.07421740521916e-09 317.668613692631 63.3280008800057 5.0162425669263 9.52381520415554e-07 -107.264162419427 113.159574899476 -0.947901779541979 0.344020841904795 DHRS7 other 4.24492711449784e-05 1 0.0105781015472556 5.0162425669263 -0.947901779541979 1.41903956454538e-16 223.966216300278 43.259658849023 5.17725341020196 4.38387155881586e-07 -300.275945486038 77.2998442652146 -3.88456080785617 0.000128800593838768 PPM1A other 1.95089559333699e-12 1 0.00498007809081481 5.17725341020196 -3.88456080785617 0.00587252580257893 86.3142404883415 33.2833789426788 2.59331363672521 0.010020194896091 -20.4397570003637 59.5549303356663 -0.343208478041367 0.731706740656994 SIX4 other 1 1 1 2.59331363672521 -0.343208478041367 0.32171245925483 -4.25925865237484 14.755135563428 -0.288662793646695 0.773059301222248 -38.6537474507353 26.8791081520277 -1.43805915107415 0.151566794899025 GALNT16 other 1 1 1 -0.288662793646695 -1.43805915107415 0.0440409159326552 63.6705163793512 26.7389528416789 2.38118959842384 0.0179427175968308 18.5717271856221 54.4227027251277 0.341249630313697 0.733178159988348 ASB2 other 1 1 1 2.38118959842384 0.341249630313697 9.77007197390701e-11 41.5088192808161 7.53099167824908 5.51173352119103 8.22453944940878e-08 -19.9053372695998 14.3087131074906 -1.3911339978701 0.16531748193344 CEP128 other 1.11225056356251e-06 1 0.000976088341855835 5.51173352119103 -1.3911339978701 2.26397976640167e-14 681.184372030058 97.4984621776549 6.98661657646304 2.16685099330735e-11 -133.053848412965 177.610818840943 -0.74913143963443 0.454425346154887 ERH essential 2.94113611453241e-10 1 2.95211779328193e-07 6.98661657646304 -0.74913143963443 1.7466571611975e-06 1714.95958025464 408.327295609966 4.19996311462061 3.62158417194597e-05 -449.386972490681 731.091168217828 -0.614679799218676 0.539280050107076 HIF1A other 0.0152622902745437 1 0.354661737958669 4.19996311462061 -0.614679799218676 0.0447039150664103 147.88034454778 121.629056128987 1.21583073366082 0.225111358098268 -297.546878375978 221.74914067383 -1.3418175036522 0.180782532551014 SUSD6 other 1 1 1 1.21583073366082 -1.3418175036522 4.35793747895817e-05 318.67595031521 162.044149998065 1.96659953672511 0.0502535154415197 -789.902855386919 295.43229354 -2.67371872560699 0.00795869440095863 SRSF5 other 0.335691924004148 1 1 1.96659953672511 -2.67371872560699 3.51843503142486e-25 1540.48320225971 148.975632128075 10.3405045526865 2.61401509218814e-21 -208.810625444325 351.128194006533 -0.594684872956799 0.552555863759978 EIF5 essential 5.39552012069002e-21 1 4.02610604498818e-17 10.3405045526865 -0.594684872956799 2.42243407046848e-21 548.941356474081 60.1627299500916 9.12427605810873 1.66965503007186e-17 -142.45580020345 133.535531362757 -1.06680071400967 0.287007795295618 DICER1 other 3.59997927212321e-17 1 2.51182902724011e-13 9.12427605810873 -1.06680071400967 4.27746486743357e-26 387.569803676669 37.179017234349 10.424423035007 1.43399571443348e-21 -83.2331839993454 87.3827013659649 -0.952513285790502 0.341698215931947 ZFYVE21 other 6.59242885368862e-22 1 2.21122139165642e-17 10.424423035007 -0.952513285790502 3.45831717373269e-21 515.201205882773 75.2594592345001 6.84566712441373 5.0159376809358e-11 -511.971069893661 139.576078493526 -3.66804308746508 0.000293792133174335 MTHFD1 other 5.13179685410193e-17 1 6.76700152535049e-07 6.84566712441373 -3.66804308746508 0.370544382665225 -15.6081561166865 11.2319057735367 -1.38962669660751 0.165787043794452 -20.2891133862908 25.0623657765519 -0.809545019300338 0.418914568326843 TCL1A og 1 1 1 -1.38962669660751 -0.809545019300338 1.67380665482922e-16 275.046921540392 37.1824518373921 7.39722390398672 1.77499837047241e-12 -111.144260098499 73.8954232540139 -1.50407501850884 0.13373520585428 ZC3H14 other 2.2972996337531e-12 1 2.4869502168689e-08 7.39722390398672 -1.50407501850884 8.07904685896496e-09 170.781074374147 48.7479107307401 3.50335166808397 0.000536979764991653 -214.11697899419 89.1371413124774 -2.4021073128606 0.0169716710144583 TELO2 essential 8.27940722106729e-05 1 1 3.50335166808397 -2.4021073128606 2.26954369959089e-10 242.899044270184 47.5689965519763 5.10624696496971 6.1866178851805e-07 -153.322062088978 87.4937169908299 -1.75237796909517 0.080835611171155 PCNX1 other 2.53893853673233e-06 1 0.00695561448830844 5.10624696496971 -1.75237796909517 0.00286422012535785 14.5557412034415 6.29386451404175 2.31268740707196 0.0214919349231326 -19.1912674851695 14.2020727744802 -1.35130046084923 0.177730354252376 BDKRB1 other 1 1 1 2.31268740707196 -1.35130046084923 5.99417282918093e-16 271.919412848292 34.545790354292 7.87127490960728 8.54510044831102e-14 -40.4404890721902 77.9523975403351 -0.518784416492963 0.604336014286207 GSKIP other 8.11850767984265e-12 1 1.22707642437746e-09 7.87127490960728 -0.518784416492963 1.92298155562703e-27 242.609399428011 21.9363792433292 11.0596829466188 1.06815226164518e-23 -30.1794504715558 49.7123217555373 -0.607081894504237 0.544306737911153 VRK1 essential 2.98235209462196e-23 1 1.66236536479839e-19 11.0596829466188 -0.607081894504237 4.58444040892525e-28 180.941642976281 15.5362815758587 11.6463931277764 1.13745951998902e-25 13.0432825956965 33.8250370971665 0.385610296841009 0.700088942172772 PSMC1 other 7.12697105971519e-24 1 1.78023789473482e-21 11.6463931277764 0.385610296841009 0.88449950876314 26.7413339843592 60.8335095535562 0.439582298976469 0.660589995447233 0.140809186846697 111.362741653887 0.00126441918325187 0.998992069976763 PAPLN other 1 1 1 0.439582298976469 0.00126441918325187 6.73145647678371e-22 382.712068304499 36.7725454636282 10.4075489874107 1.46496936700816e-21 130.322972713926 79.0082417469591 1.64948579834637 0.100206754434674 RPS6KA5 other 1.0064873724087e-17 1 2.25883626698988e-17 10.4075489874107 1.64948579834637 3.91105848849384e-28 665.465388991802 60.7591512879259 10.9525129118129 2.28403644750254e-23 -161.367633656217 130.078734347272 -1.24053815918452 0.215845387424206 PPP4R3A other 6.08208705545677e-24 1 3.55213348315596e-19 10.9525129118129 -1.24053815918452 7.16359334089524e-10 32.1973852040815 7.99646331692298 4.02645318661589 7.34915494700994e-05 -37.1034460722548 15.6048981187538 -2.37767948178171 0.0181133627294673 C14orf93 other 7.80545130423945e-06 1 0.699345584757466 4.02645318661589 -2.37767948178171 1.3340967125857e-21 873.767219387753 120.148247783391 7.27240917373198 3.76916653451399e-12 -635.786985922912 234.466299850176 -2.71163483336062 0.00712161061964969 PSMB5 essential 1.98767069208143e-17 1 5.24215681620206e-08 7.27240917373198 -2.71163483336062 2.28815510968093e-09 625.013844305682 137.01408859827 4.56167574225338 7.67372714158726e-06 -402.86750873607 270.512803631716 -1.48927334798003 0.137569717705817 ACIN1 essential 2.42498678523985e-05 1 0.0794921394597024 4.56167574225338 -1.48927334798003 5.28151971896135e-15 280.024303675316 43.9580168814985 6.37026698520549 8.01911763972687e-10 -206.948625415996 99.147382978548 -2.08728278244895 0.0377933588425659 CCNB1IP1 other 6.98850689212966e-11 1 1.03951821963779e-05 6.37026698520549 -2.08728278244895 2.72465313852332e-20 265.707373408095 30.1781181204071 8.80463693421685 1.5659792644359e-16 -81.2792997833611 64.6080685275324 -1.25803636659908 0.20945748845397 TRIP11 other 3.99679368889985e-16 1 2.33456188742104e-12 8.80463693421685 -1.25803636659908 9.00074653346662e-25 1009.07991472914 117.593032543894 8.58111992606772 7.30477443572992e-16 -693.852220315615 250.751239052301 -2.76709388531035 0.00604384322419303 APEX1 other 1.37603413003638e-20 1 1.0797917570896e-11 8.58111992606772 -2.76709388531035 1.97518031344981e-09 600.702789271632 127.831823187536 4.69916468601384 4.15324655236742e-06 -373.955982027625 259.249908610259 -1.44245366963584 0.150324928607309 PABPN1 essential 2.10080178138522e-05 1 0.0439787277430186 4.69916468601384 -1.44245366963584 1.3651713020823e-06 298.881291832309 89.1170859757652 3.35380458819746 0.000910390722972838 -318.639340048074 180.734310273707 -1.76302628740233 0.0790189453112699 EFS other 0.012027159171345 1 1 3.35380458819746 -1.76302628740233 3.36248238794587e-18 325.859185680356 70.815346451483 4.60153345297277 6.51870245127587e-06 -643.832481950222 130.13477308043 -4.94742847518779 1.3406610360779e-06 ARHGAP5 other 4.78178620389782e-14 0.0209371034004285 0.0679965852692586 4.60153345297277 -4.94742847518779 2.69883763799249e-28 244.967189285881 22.6365233093469 10.8217673685222 6.77732883204338e-23 -58.5212477750043 50.0924512329694 -1.16826480506682 0.243734312983601 CINP essential 4.19885159718871e-24 1 1.05129924842657e-18 10.8217673685222 -1.16826480506682 0.0985432273771943 550.572089932804 306.131069213147 1.79848484947296 0.0732047842797317 -43.9465067165778 621.774701603045 -0.0706791488995546 0.943704863386756 DHRS2 other 1 1 1 1.79848484947296 -0.0706791488995546 1.21101076884524e-19 235.709538354145 40.6592378723176 5.79719519323862 1.91196346038474e-08 -297.888195292779 75.7437654861388 -3.93284111742891 0.000107256345651041 SRP54 essential 1.76129406220852e-15 1 0.0002340625668203 5.79719519323862 -3.93284111742891 8.90042294851339e-23 576.411000125659 69.1335115192805 8.33764967898246 3.86117223122045e-15 -289.38372063555 147.747036234669 -1.9586431512299 0.0511801030642518 CHD8 other 1.34102672565251e-18 1 5.65932013929981e-11 8.33764967898246 -1.9586431512299 6.66509467348729e-08 216.471315625542 60.5528932373405 3.57491284152303 0.000414426089021184 -255.464681835104 120.52043002238 -2.11967947498749 0.034938822580088 PCK2 other 0.000645447768180509 1 1 3.57491284152303 -2.11967947498749 2.92887350772394e-13 446.073045102777 87.7249596147908 5.08490453642304 6.96357756491374e-07 -414.708730969189 164.439926675603 -2.52194670329246 0.0122573030619699 KIAA0391 other 3.67749357629817e-09 1 0.00780199230372935 5.08490453642304 -2.52194670329246 6.67277464562123e-19 195.901211224755 49.2350777965193 3.97889512908628 8.88552352682945e-05 -547.324775511934 97.9942068988153 -5.58527685291722 5.65348308383978e-08 DCAF11 other 9.60545910237176e-15 0.000894889837340999 0.837371737168408 3.97889512908628 -5.58527685291722 9.61910667527512e-10 693.525945942437 147.92063866 4.68850021352683 4.40903963869265e-06 -425.231407300994 277.27637700682 -1.53360128219843 0.126320745045259 PSMA6 essential 1.04001781373075e-05 1 0.046594730901704 4.68850021352683 -1.53360128219843 0.359549454635815 467.918633481245 421.494594132949 1.11014148222659 0.267944388394611 -134.412330083015 790.089165703063 -0.170122988540676 0.865043220359825 NFKBIA other 1 1 1 1.11014148222659 -0.170122988540676 4.39992751453639e-16 92.8809668209858 16.1441186098418 5.75323862922834 2.35325401921948e-08 -90.3688757652293 32.1321742557233 -2.81241085791551 0.00527533697246998 EMC9 other 5.9790614995035e-12 1 0.000286814599862471 5.75323862922834 -2.81241085791551 3.52770869548559e-23 115.993507681054 14.4261798147912 8.04048675187908 3.09345220493972e-14 -60.8431922092174 26.962276275683 -2.2566044345481 0.0248571802169469 BRMS1L other 5.33424831844376e-19 1 4.47344123356333e-10 8.04048675187908 -2.2566044345481 0.690920715435981 -18.1046590603475 38.2403756288866 -0.473443546581465 0.636276518557157 -65.5228440279151 76.1608769577173 -0.860321554126691 0.390369485187329 REC8 other 1 1 1 -0.473443546581465 -0.860321554126691 4.02223252076492e-28 473.573181571616 56.1099098855734 8.44009877287965 1.90862543323817e-15 -390.888015413205 111.750469827385 -3.49786462658268 0.000547658940387018 TM9SF1 other 6.25457156978946e-24 1 2.80854232500997e-11 8.44009877287965 -3.49786462658268 2.59360789376464e-12 340.987395628543 66.0567743555001 5.16203521827207 4.85781051297184e-07 -250.202090865635 123.40355415127 -2.0275112219129 0.0436301651853744 SEC23A other 3.14682445750464e-08 1 0.00549515525227374 5.16203521827207 -2.0275112219129 1.92817505173214e-25 325.440568062038 40.558424262732 8.0239943730032 3.07968967380799e-14 -250.451384706119 79.4837527471828 -3.15097584160048 0.00180902645889348 GMPR2 other 2.96167687946057e-21 1 4.45384720626112e-10 8.0239943730032 -3.15097584160048 8.22885562252937e-06 533.853962086704 145.616608487835 3.66616121354937 0.000298499997594599 -224.919055938011 272.032765846923 -0.826808694304775 0.409103638513129 PNN essential 0.0678798300302448 1 1 3.66616121354937 -0.826808694304775 1.13833562187429e-12 139.671237388947 28.5998279501422 4.88363907756489 1.77906455459036e-06 -143.205313582292 56.0480761943671 -2.55504422820287 0.0111621617382766 RABGGTA essential 1.39958364709444e-08 1 0.019382908322262 4.88363907756489 -2.55504422820287 0.0468882323454766 52.3908485167894 50.4497280597656 1.03847633142292 0.299970614155551 -134.49907518948 98.8680843538005 -1.36038921021442 0.174833085266802 NFATC4 other 1 1 1 1.03847633142292 -1.36038921021442 0.000157808430976932 1098.30568158214 310.242964372047 3.54014694194657 0.000470802904311835 -1270.98330618448 1028.54393107819 -1.23571124944769 0.217639961938477 PLTP other 1 1 1 3.54014694194657 -1.23571124944769 7.89886499464709e-21 263.009418285577 29.080528993977 9.04417585870084 3.03503425978266e-17 -242.412842009257 96.4102495276227 -2.51438870034044 0.01250567605229 PCIF1 other 1.16705730295911e-16 1 4.55255138967399e-13 9.04417585870084 -2.51438870034044 1.42207011051614e-16 472.570579179367 53.8839906658536 8.77014811523296 2.14292212419185e-16 -202.435792518545 251.314472224502 -0.805507899034587 0.421243418165273 GSS other 1.95477757391548e-12 1 3.19102533513409e-12 8.77014811523296 -0.805507899034587 0.375576361970718 317.803147900409 354.208464892519 0.897220646595339 0.37039755761254 -908.490529759357 1177.23807203837 -0.771713514316031 0.440956523061517 MMP9 other 1 1 1 0.897220646595339 -0.771713514316031 6.43019808751129e-33 549.160449556283 42.3742690379087 12.9597621864579 4.18544529512916e-30 -546.798910700148 197.664370300405 -2.76629981351286 0.00606707218550665 TRPC4AP other 1.01294910472565e-28 1 6.60212140853674e-26 12.9597621864579 -2.76629981351286 0.00270065519219795 452.537031646072 236.011052105592 1.91743999956242 0.0562735296581102 -1721.65702681785 780.327842997881 -2.20632525452835 0.0282324542388354 PYGB other 1 1 1 1.91743999956242 -2.20632525452835 1.44881077663487e-08 240.453197471627 49.1156469574665 4.89565367386601 1.71858869338413e-06 -362.479480515272 162.464994497104 -2.23112358226641 0.0265227205181616 ABHD12 other 0.000146011150069262 1 0.0187377725239671 4.89565367386601 -2.23112358226641 0.0017470955848575 160.094983328672 46.2936253540406 3.45825115454472 0.000633278639981674 -57.3377379823442 204.355054982327 -0.280579004944619 0.779252241664702 PROCR other 1 1 1 3.45825115454472 -0.280579004944619 2.30695954773432e-08 193.633895295092 34.4597829832178 5.61912695124614 4.9163387609723e-08 -80.1932556488956 113.986250808996 -0.703534462092919 0.482349868673723 GINS1 essential 0.00022984237974077 1 0.00059114057261931 5.61912695124614 -0.703534462092919 0.000321085403705616 117.021900511405 30.7183101210938 3.80951621525063 0.000173676164476644 -26.2978193143266 101.610187260807 -0.258810853746652 0.795985175797893 NINL other 1 1 1 3.80951621525063 -0.258810853746652 0.0063503265453271 118.24814901073 55.7715073520392 2.12022508669755 0.0348957279314475 -314.153274059378 185.360736112591 -1.69482103193935 0.0912580768672913 CD40 other 1 1 1 2.12022508669755 -1.69482103193935 1.23268131644839e-25 235.255607275609 21.0841311591209 11.1579464906638 5.72287705503436e-24 -178.770385661716 93.2067007939801 -1.91799928694893 0.0561816954488356 UQCC1 other 1.89561732843434e-21 1 8.91395330092152e-20 11.1579464906638 -1.91799928694893 1.72781008969154e-06 363.843851914481 74.9198429955852 4.85644172980876 2.03032715082106e-06 -145.984125066865 248.397936204983 -0.587702648811044 0.557224913219167 ZMYND8 essential 0.0151045158040834 1 0.022035140567861 4.85644172980876 -0.587702648811044 0.228594819461418 1.72716087986977 4.50245151275579 0.383604548539077 0.701571233596372 -23.8123438353882 15.5801265898849 -1.5283793554571 0.127580425515945 SGK2 other 1 1 1 0.383604548539077 -1.5283793554571 9.34157396477546e-17 224.765718013833 26.7781377299573 8.39362767793904 2.61414132047295e-15 -143.532412102155 92.662136281119 -1.54898665045564 0.122547632610645 IFT52 other 1.2898845330562e-12 1 3.84017359977476e-11 8.39362767793904 -1.54898665045564 1.97282158783249e-11 793.010470503852 110.122474297307 7.2011682952464 5.85374616198461e-12 146.785970349118 383.035737681999 0.383217428319916 0.701857886624244 MYBL2 essential 2.31411972252751e-07 1 8.09631631664092e-08 7.2011682952464 0.383217428319916 0.913811945044675 0.03850485313886 20.2124965996102 0.00190500233106298 0.998481425361696 -28.5277997930641 69.6860185693758 -0.409376233263538 0.682585761225284 HNF4A other 1 1 1 0.00190500233106298 -0.409376233263538 8.15830192971921e-11 196.893156297 31.3972850608602 6.27102489643116 1.4234488965512e-09 -226.517372513145 130.541698136822 -1.73521086171048 0.0838487378076958 NDRG3 other 9.32004412451123e-07 1 1.83012824629588e-05 6.27102489643116 -1.73521086171048 1.32817522988022e-05 68.2978901121715 19.2209790392798 3.55329923478917 0.00044915015396988 -185.017418018281 79.9158028720049 -2.31515434205935 0.0213572854760506 SLA2 other 0.10766188413409 1 1 3.55329923478917 -2.31515434205935 5.12814220392488e-07 612.631814562856 134.982308418944 4.53860822013379 8.54569391594452e-06 -1095.33217469389 561.221128682982 -1.9516944724877 0.0520121310707059 C20orf24 other 0.00467840413264066 1 0.0882171982942953 4.53860822013379 -1.9516944724877 0.536793739849879 2.90298921578877 37.0356547548177 0.0783836342305017 0.937581165562305 -128.316265312532 120.882434660508 -1.06149636771382 0.289416461628893 NFATC2 other 1 1 1 0.0783836342305017 -1.06149636771382 3.09553427779468e-07 126.63121865173 22.4945904904024 5.62940759938525 4.49891140336122e-08 118.645387279489 76.8696204454912 1.54346263962135 0.123881173287812 RIMS4 other 0.00287327491664902 1 0.000541578954736624 5.62940759938525 1.54346263962135 7.62566532338716e-07 265.099630311947 52.2801634073148 5.07074984151359 7.33920518290188e-07 -96.586744808088 178.654344459536 -0.540634738552156 0.589201801644078 PABPC1L other 0.00685471055919272 1 0.00821183667914892 5.07074984151359 -0.540634738552156 3.39258748627564e-13 199.213980143176 31.0704694621442 6.41168233347409 6.33664449877575e-10 -303.29546194521 106.175535653218 -2.85654750954881 0.00461326455034366 STK4 other 4.25023360280613e-09 1 8.24460815735713e-06 6.41168233347409 -2.85654750954881 8.48690948050791e-07 79.4882395661292 14.7012968497125 5.40688623450821 1.41185997067908e-07 40.9344867862457 46.5314211442336 0.879717098245526 0.379794882641464 SALL4 other 0.00759578398505458 1 0.00165498225763002 5.40688623450821 0.879717098245526 4.76094372496749e-12 563.032411267809 88.4550909936839 6.3651781366435 8.37588519120039e-10 -646.978996725038 292.929030809793 -2.2086544134478 0.0280419496953307 ADNP other 5.70837152623602e-08 1 1.08509592652001e-05 6.3651781366435 -2.2086544134478 7.3809841757003e-13 144.868680193391 20.9610997008315 6.91131106006066 3.45392350542257e-11 -114.276110426972 64.7414830034965 -1.7651141914806 0.0786749948058173 PFDN4 other 9.1443012952751e-09 1 4.67833938809486e-07 6.91131106006066 -1.7651141914806 0.658542845916883 -2.57141817663769 3.64360569983857 -0.705734480751201 0.480959483387163 -8.48243679720958 11.2895091616273 -0.751355676829697 0.453090608123476 DOK5 other 1 1 1 -0.705734480751201 -0.751355676829697 4.89736641135273e-23 178.435100934016 19.3543948579001 9.21935830306684 8.8141802697697e-18 -207.246667593729 58.6651977862614 -3.53270210302204 0.000483652270167817 CSTF1 essential 7.39600275442489e-19 1 1.32882581747048e-13 9.21935830306684 -3.53270210302204 0.302559302597204 218.829497833453 145.768508027374 1.50121244152653 0.134473483968161 31.9019157401322 454.427891453037 0.0702023716856939 0.944084747067861 BMP7 other 1 1 1 1.50121244152653 0.0702023716856939 2.22520992338998e-18 328.456192750763 37.6529659231448 8.72324887822093 2.8732782942734e-16 -188.199891793986 117.381718060766 -1.60331519169415 0.110038562982859 RAE1 essential 3.1742619557158e-14 1 4.27170284009626e-12 8.72324887822093 -1.60331519169415 4.03238201195477e-16 868.644462910035 113.563540786912 7.64897304972144 3.64951301861018e-13 -848.161912303185 319.783703971482 -2.65229873120371 0.00847128033397715 TPD52L2 other 5.48645896546567e-12 1 5.19471683068973e-09 7.64897304972144 -2.65229873120371 1.0341955455215e-05 309.135325404717 101.484549664611 3.04613191294988 0.00254918954282282 -837.305453184784 285.770459099379 -2.92999302945307 0.00368164477650867 DNAJC5 other 0.084597195623659 1 1 3.04613191294988 -2.92999302945307 1.85096773392308e-12 637.694828308803 93.7610278451864 6.80127813190928 6.5717653988351e-11 -481.580856910412 278.687694197015 -1.72803057665677 0.085117693611018 NELFCD essential 2.25910611925312e-08 1 8.84033881451298e-07 6.80127813190928 -1.72803057665677 0.00396999406561148 307.200795353045 234.078993465162 1.31238087965705 0.190498010485361 -1829.9801138982 695.757463927089 -2.63019832165245 0.00901974560515488 CTSZ other 1 1 1 1.31238087965705 -2.63019832165245 1.88305762583943e-18 845.984316493915 92.9075673465253 9.10565566030348 2.07244168942862e-17 -286.814558917291 261.57378242491 -1.09649581949073 0.273849830178558 PRPF6 essential 2.69051273579937e-14 1 3.11508710338016e-13 9.10565566030348 -1.09649581949073 0.392618026377047 1.37028292494211 5.0858439102141 0.269430786538712 0.787802473984275 -18.479206467506 15.1167510100655 -1.22243241654252 0.222602352856305 TUBB1 other 1 1 1 0.269430786538712 -1.22243241654252 3.74802047296144e-08 403.61055767637 100.814810840298 4.00348474903887 8.05660031426789e-05 -984.707797076877 299.653788142993 -3.2861516724994 0.00114903334354686 PRELID3B other 0.000368617813515758 1 0.763362879776882 4.00348474903887 -3.2861516724994 5.74670260285326e-19 180.428572995804 20.7156535975087 8.70976974713959 3.06226549901226e-16 -118.305006915413 58.7683397269073 -2.0130738330395 0.0450956266586488 MTG2 essential 8.28042378045127e-15 1 4.54991407843242e-12 8.70976974713959 -2.0130738330395 4.33970128323525e-13 1037.88240585832 159.750300723301 6.49690423842147 3.91062017990721e-10 -1136.1304015641 453.196414981162 -2.50692716007324 0.0127642988778951 PSMA7 essential 5.41638117160591e-09 1 5.12682305585835e-06 6.49690423842147 -2.50692716007324 0.0137847106270628 86.4568857636386 38.2739457239115 2.25889659736924 0.024684757785114 -126.518292265005 107.176873264827 -1.1804626167101 0.238851343079265 SLCO4A1 other 1 1 1 2.25889659736924 -1.1804626167101 0.5010111286838 -2.5414581290955 6.17623102393905 -0.411490133585486 0.681038415759675 -20.3098911304886 17.295032356527 -1.17431934857432 0.241298029144565 NTSR1 other 1 1 1 -0.411490133585486 -1.17431934857432 4.05502329776185e-14 230.134476988156 29.1010235286924 7.90812312018006 6.65255502194001e-14 -19.9828305456875 81.4903363533498 -0.24521718083283 0.806473863656537 MRGBP essential 5.23462957508077e-10 1 9.56770463255413e-10 7.90812312018006 -0.24521718083283 9.32848520623289e-13 107.070012712926 15.1695256570498 7.05823076696979 1.41381742310828e-11 -60.2932362537224 42.6179528096518 -1.41473797493313 0.158293297119274 TCFL5 other 1.15132164415326e-08 1 1.93692986965835e-07 7.05823076696979 -1.41473797493313 2.05844354003104e-13 376.044017087869 52.2627100387035 7.19526440189166 6.11608571838074e-12 -237.881760320072 146.829225942135 -1.62012541300068 0.106368357716838 DIDO1 essential 2.59919665799719e-09 1 8.45610011423321e-08 7.19526440189166 -1.62012541300068 1.16414954920549e-16 681.727964197855 84.2352101976143 8.09314730263667 1.97291863892249e-14 -479.492770516914 236.654216768121 -2.02613237602579 0.0437307315231286 GID8 other 1.60349958907565e-12 1 2.86171848575707e-10 8.09314730263667 -2.02613237602579 0.101688963382324 34.7841827420701 21.6061768506487 1.60991844982634 0.108579837830396 -57.1678965672069 60.7013723589971 -0.941789194305317 0.347139346781312 SLC17A9 other 1 1 1 1.60991844982634 -0.941789194305317 0.137743117852172 0.157477373504212 1.67538265681238 0.0939948690908811 0.925182434019488 -8.90513120330439 4.69059638098727 -1.89850724300223 0.058687632241925 BIRC7 other 1 1 1 0.0939948690908811 -1.89850724300223 0.462896892746413 -2.86515215938772 7.21783779415071 -0.396954356844874 0.691712402340662 -25.0796407094698 20.2078991913475 -1.24108104815805 0.215645103008617 NKAIN4 other 1 1 1 -0.396954356844874 -1.24108104815805 1.63806295207547e-09 443.291827127497 75.8463304968541 5.84460479793263 1.44927999839223e-08 -297.836989005649 212.348219013198 -1.40258764773129 0.16188016184255 ARFGAP1 other 1.7492874265214e-05 1 0.000178609267001858 5.84460479793263 -1.40258764773129 0.0266192482803494 258.318723401514 98.4699085402382 2.6233265292001 0.0091990431382099 373.994511463776 275.723076320672 1.35641353075871 0.176092432525247 EEF1A2 other 1 1 1 2.6233265292001 1.35641353075871 0.249727589985112 -29.7221180773845 70.0760848000387 -0.424140677410792 0.671799707291078 -327.655380922443 196.209610756056 -1.66992523791208 0.0960887533494242 PTK6 other 1 1 1 -0.424140677410792 -1.66992523791208 8.22717214033662e-10 116.475535234612 20.9322307650818 5.56441100529577 6.31430509890101e-08 -127.055210226515 58.6092225670456 -2.16783647114874 0.0310416851475268 GMEB2 other 8.9355316616196e-06 1 0.000754054314910759 5.56441100529577 -2.16783647114874 4.6921615036123e-14 296.613933971592 39.497058164389 7.50977282249902 8.59810186194018e-13 -251.370065742133 142.797863085024 -1.76032092015595 0.0794814504710205 C20orf27 other 6.043973232803e-10 1 1.21267628660804e-08 7.50977282249902 -1.76032092015595 0.205533716062072 1.2005811850387 2.97693231730241 0.403294753481874 0.687049405246829 -17.2547525159921 10.7628160986128 -1.60318195144262 0.110059323887883 SPEF1 other 1 1 1 0.403294753481874 -1.60318195144262 7.69871518966473e-14 977.40266959269 122.05467905255 8.00790823571682 3.46092002353127e-14 -14.6057210669655 441.277101593022 -0.0330987513610801 0.973620203035919 CDC25B other 9.84819647061913e-10 1 5.00068334200033e-10 8.00790823571682 -0.0330987513610801 0.550740962403417 -11.5018364643545 10.7063163960348 -1.07430380710721 0.283660082277858 -18.8339053468208 37.7935817712634 -0.498336078882612 0.618658970699031 ISM1 other 1 1 1 -1.07430380710721 -0.498336078882612 1.06730472340657e-08 257.01795403574 44.6676755450499 5.75400333461549 2.3517252169406e-08 -183.673351215152 161.491739214117 -1.13735446846371 0.256394738222986 RNF24 other 0.00010857690951215 1 0.000286651786692889 5.75400333461549 -1.13735446846371 5.48459918723928e-07 175.107422566313 37.1836202321539 4.70926234382341 3.97401057269245e-06 -159.169685408875 104.123681992349 -1.52865978577833 0.127515154045846 ARFRP1 other 0.00498933988063157 1 0.0421682261868396 4.70926234382341 -1.52865978577833 4.19490336198639e-07 44.0120157765795 9.54859178905363 4.60926770657787 6.27834371251701e-06 -59.0706934682117 33.521794730164 -1.76215784219506 0.0791911844421829 NDUFAF5 other 0.00385595517033789 1 0.0655207949838275 4.60926770657787 -1.76215784219506 9.35042190821407e-12 526.742598345189 71.4783075357269 7.36926511699941 2.20449051493588e-12 -6.40622856313422 271.097916929043 -0.0236306816212498 0.981165049762318 TRIB3 other 1.10998858472409e-07 1 3.08143684177737e-08 7.36926511699941 -0.0236306816212498 0.871511235384275 -8.67910420893926 54.7529388773737 -0.158513942573516 0.87416902830846 89.6358310663976 199.776091672465 0.448681472922979 0.654017378803953 RASSF2 other 1 1 1 -0.158513942573516 0.448681472922979 6.03553616032787e-33 843.781988677604 61.917373793991 13.6275480850496 2.2135957212663e-32 -299.530736785351 234.835877288755 -1.27548967493177 0.2032571781788 CSNK2A1 other 9.50898722059656e-29 1 3.50035891403841e-28 13.6275480850496 -1.27548967493177 0.000178463184088716 58.4224084954329 17.1311437673829 3.41030402223738 0.00074891595646151 -121.476724515668 64.9542015651781 -1.87019040475423 0.0625474241883074 SLC52A3 other 1 1 1 3.41030402223738 -1.87019040475423 0.106227218579211 27.3079908477193 13.292829451206 2.05433996937663 0.0409053587809298 -9.41987803875584 50.6719742519924 -0.185899171638955 0.852663416415045 RSPO4 other 1 1 1 2.05433996937663 -0.185899171638955 1.56346144119052e-14 288.895449822427 39.7565951696767 7.26660441090223 3.90722743187588e-12 -344.599115172757 143.538993076758 -2.40073521338192 0.01703407482454 CDS2 other 2.03937910388891e-10 1 5.43182757579385e-08 7.26660441090223 -2.40073521338192 8.0309124075613e-13 709.089633118209 110.305425669917 6.42842025958105 6.37644739754601e-10 -1636.34747659748 499.467766063 -3.27618234404958 0.00119941097971142 HM13 other 9.93584483063484e-09 1 8.2951204194676e-06 6.42842025958105 -3.27618234404958 0.146070905026905 25.2410351649284 13.9852451598601 1.8048332279061 0.0722148573289592 -26.8995268344452 53.5074061104904 -0.502725300847118 0.615567221679948 SNPH other 1 1 1 1.8048332279061 -0.502725300847118 0.861267524578854 -0.849788507538987 15.8865706178331 -0.0534909973953144 0.957379825097682 33.1642020213992 62.676551343623 0.529132527403704 0.597143485058049 SIRPB1 other 1 1 1 -0.0534909973953144 0.529132527403704 9.05501489867969e-18 375.387995415421 48.0249053512662 7.81652754273515 1.21894261659437e-13 -510.676835473537 162.103909177052 -3.1503054927304 0.0018144235721048 SEC23B other 1.2776626022037e-13 1 1.74674476957973e-09 7.81652754273515 -3.1503054927304 7.64233035316152e-05 371.36583268531 109.774589462892 3.38298539308904 0.000822459687096269 -793.470505855669 401.160886195818 -1.97793586852422 0.0489450519219684 FERMT1 other 0.574091856129493 1 1 3.38298539308904 -1.97793586852422 0.836319939328284 5.04396335240629 8.52959611945069 0.59134843921908 0.554810815255286 7.75425414808103 38.7160341863923 0.20028534200454 0.84141706475915 CCM2L other 1 1 1 0.59134843921908 0.20028534200454 1.46279054996345e-05 166.307584358777 36.4082322668139 4.56785660836289 7.56793186706883e-06 -48.4871479063794 134.091855356963 -0.361596517382081 0.717942799347974 PLCB4 other 0.118193476437047 1 0.0784567496659025 4.56785660836289 -0.361596517382081 0.216026282844525 431.226846480495 252.015796009667 1.71111038795344 0.0882134927917647 40.146062726977 1047.81575555449 0.0383140475929686 0.969465709149522 MYL9 other 1 1 1 1.71111038795344 0.0383140475929686 0.366838079287946 29.2414847949933 73.5587848169044 0.397525392348153 0.69131132334459 502.448268875874 355.817204452777 1.41209661193479 0.159135913801982 HCK other 1 1 1 0.397525392348153 1.41209661193479 5.99309537511665e-14 555.132502206534 74.2820285751683 7.47330832039378 1.23894915071651e-12 -773.334841129744 359.315665892072 -2.15224359675437 0.0323132680497404 TM9SF4 other 7.69273722349973e-10 1 1.74208640082249e-08 7.47330832039378 -2.15224359675437 0.167689408225569 -11.4925478809377 10.6572372735669 -1.07837965749741 0.281830397020599 -75.0751805815802 41.9713785410529 -1.78872324882415 0.0747845702350176 TLDC2 other 1 1 1 -1.07837965749741 -1.78872324882415 8.83940134160707e-20 212.550589405728 24.4590790472718 8.69004875428602 3.50778493651817e-16 -219.186496950914 80.2247758900446 -2.73215468063544 0.00670564433129084 CRNKL1 essential 1.28798916948557e-15 1 5.20870985223583e-12 8.69004875428602 -2.73215468063544 0.211117910414987 -181.756314991489 128.272363787126 -1.4169561519356 0.157652837441951 -704.69099380659 505.174821453815 -1.39494480698503 0.164183194576532 SAMHD1 other 1 1 1 -1.4169561519356 -1.39494480698503 0.0214368685294719 23.7747804703442 10.9333709460291 2.17451512325931 0.030557996598029 -40.6560601341585 39.8899027875726 -1.0192067990405 0.309041434501851 PAK5 other 1 1 1 2.17451512325931 -1.0192067990405 2.06222790051091e-14 284.258420322624 37.9335844163654 7.49358186673203 1.06104362807372e-12 -437.22504745271 186.432346478863 -2.34522096465852 0.0197710457227336 KIF3B other 2.68192738461444e-10 1 1.49373721960218e-08 7.49358186673203 -2.34522096465852 4.27512269411424e-16 43.3810985483418 5.11497527054036 8.48119419035998 1.50256462893714e-15 -14.3814401987266 19.57959538539 -0.734511613526894 0.463276774979252 MROH8 other 5.81202930264832e-12 1 2.21282692903573e-11 8.48119419035998 -0.734511613526894 5.59118193151092e-15 280.426604236571 38.1627759804319 7.3481710130406 2.39123415772789e-12 -361.318548712911 146.061066298356 -2.4737499038577 0.0139857026874501 MANBAL other 7.38762868610538e-11 1 3.34079324176164e-08 7.3481710130406 -2.4737499038577 2.67843180051028e-25 440.752478909567 41.4456606139105 10.634466247635 2.50775047316627e-22 -425.663161213209 153.929621938551 -2.76531024927181 0.00607461994427383 IDH3B other 4.10898222516282e-21 1 3.87923920694091e-18 10.634466247635 -2.76531024927181 4.13820374785888e-29 901.476132516379 72.8019523673523 12.3825818292291 3.75917254345135e-28 -457.09289086365 367.996160849893 -1.24211320522471 0.215280639970814 MAPRE1 other 6.46097751153207e-25 1 5.91129882457725e-24 12.3825818292291 -1.24211320522471 6.24933638599233e-07 2026.62955991658 425.900056891018 4.75846275933972 3.23334279245817e-06 -1817.02414984106 1518.11133252732 -1.19689782357142 0.232432396691487 JAG1 other 0.00565877409751606 1 0.0345256343378683 4.75846275933972 -1.19689782357142 2.92205221301202e-30 200.372311392121 15.4639297446871 12.9573992316515 3.65487344283275e-30 -8.69628045774989 77.9500013775871 -0.111562287415819 0.911253673018607 CDK5RAP1 other 4.58002463867504e-26 1 5.76556285606866e-26 12.9573992316515 -0.111562287415819 7.20215653079406e-08 111.967851039148 19.7918900704566 5.65725914203025 3.92985233637219e-08 -44.674387456567 99.4630745647948 -0.449155504714104 0.653681132489068 SNTA1 other 0.000696016407135938 1 0.00047397949028985 5.65725914203025 -0.449155504714104 3.08002596488311e-26 265.4640319607 23.7679498274513 11.1689915995235 4.61072351855954e-24 -141.954890269075 85.2440446052805 -1.66527633603488 0.097017491186232 TTI1 essential 4.74940003784975e-22 1 7.18396831426761e-20 11.1689915995235 -1.66527633603488 7.93794029256368e-11 167.090293089317 24.1193684432164 6.92763964706181 3.15272770709105e-11 -15.1852994500265 121.1519064745 -0.125340986303197 0.900347226868713 E2F1 other 9.07385954842955e-07 1 4.27478349804476e-07 6.92763964706181 -0.125340986303197 6.85311812391056e-23 290.387744008133 29.7759024294378 9.75244141453938 1.90730575640323e-19 -283.328538921863 106.791640561522 -2.65309660411704 0.00844823250513346 RPRD1B essential 1.03365580662943e-18 1 2.91093004542262e-15 9.75244141453938 -2.65309660411704 0.00242202961533103 53.8637754677073 24.0267829942044 2.24182219819857 0.0257882260014627 -249.024932249726 116.323252140834 -2.1408009806004 0.0331890916826256 PXMP4 other 1 1 1 2.24182219819857 -2.1408009806004 1.67228529473195e-15 635.677626600846 87.0873326035039 7.29931216856755 3.26625835656713e-12 -1343.5000868495 421.06353001826 -3.19073011806849 0.00158737540483341 CHMP4B essential 2.23969169523451e-11 1 4.5492446390267e-08 7.29931216856755 -3.19073011806849 0.114740338139974 257.325985443352 208.328588475864 1.23519286203566 0.217840480167828 -839.423564552734 683.315653037104 -1.2284565132114 0.220353325291114 CST3 other 1 1 1 1.23519286203566 -1.2284565132114 0.67514295993182 -82.4608100271104 99.3655777330896 -0.829872999366161 0.407349189784051 -179.674395830867 325.918085150188 -0.55128697675083 0.581896283496346 CST4 other 1 1 1 -0.829872999366161 -0.55128697675083 4.91972960758211e-18 77.0350886285891 8.72598874452618 8.82823607547205 1.37013903543089e-16 -44.9515676093372 31.7644365061739 -1.4151539442735 0.158175686964463 ACTR5 other 6.97568461059067e-14 1 2.04356237134517e-12 8.82823607547205 -1.4151539442735 0.0171704599596146 -211.092556835877 209.395044024514 -1.00810674779468 0.314302472914384 -2047.41292432264 715.066385153522 -2.86324873722468 0.00452086555121192 WFDC2 other 1 1 1 -1.00810674779468 -2.86324873722468 5.36261303620333e-15 2051.09734245352 251.290432952957 8.16225798312624 1.33946011799417e-14 -1032.24958191363 1081.68459108101 -0.954298129440875 0.340802431037026 AHCY essential 7.09172970920046e-11 1 1.94797684959893e-10 8.16225798312624 -0.954298129440875 0.35686940268782 -34.4983414533016 24.020910499066 -1.43617959255304 0.152108845037734 -26.1138648849856 87.4411724226327 -0.298644953646876 0.765440677785636 PPP1R16B other 1 1 1 -1.43617959255304 -0.298644953646876 0.000165219593439625 283.938702878269 72.0527095213234 3.94070819493942 0.000103530349356501 -128.363713322718 262.287035165336 -0.489401671118825 0.624954705844008 FAM83D other 1 1 0.969458191374279 3.94070819493942 -0.489401671118825 1.43825959862152e-06 137.555617448806 28.6868248196248 4.7950799125982 2.69054062635674e-06 -101.562827796181 104.87576158645 -0.968410872634878 0.333705875317888 DHX35 other 0.0126480549102777 1 0.0289286928145877 4.7950799125982 -0.968410872634878 3.15493687959575e-14 188.00968575704 26.7810288883045 7.02025626204173 1.78006033761691e-11 -208.496662585589 87.7225878138337 -2.37677282193343 0.0181595799739218 DNTTIP1 other 4.08532776538853e-10 1 2.43227444531975e-07 7.02025626204173 -2.37677282193343 0.0371776850066069 24.3933834441209 20.7238140997095 1.17707017283382 0.240223630172925 -182.100803231935 91.6884997836102 -1.98608117333911 0.0480545267016863 MAP1LC3A other 1 1 1 1.17707017283382 -1.98608117333911 0.129662718611809 22.3507921254615 12.0922501678633 1.84835674214395 0.0656647733567351 53.7889137267598 39.5281322981782 1.36077549328681 0.174740813013874 SYNDIG1 other 1 1 1 1.84835674214395 1.36077549328681 9.49044122720164e-18 189.487660173142 22.0632639519763 8.58837842785128 7.66676605055706e-16 -215.261370160529 97.6146361067228 -2.20521613096198 0.028297888430666 PIGU other 1.33872163950906e-13 1 1.13291801929082e-11 8.58837842785128 -2.20521613096198 0.0680853836303784 3.24396227270668 1.60093380287934 2.02629382106386 0.0437140790758972 -2.79046992850555 5.24393803886108 -0.532132513356624 0.59507020182083 TNNC2 other 1 1 1 2.02629382106386 -0.532132513356624 3.29076786411915e-20 123.124263427753 14.6846277205952 8.38456825535117 2.85069824296389e-15 -162.429065730436 48.683730033111 -3.33641373863432 0.000967792946412461 ACOT8 other 4.82196215129379e-16 1 4.18482502067099e-11 8.38456825535117 -3.33641373863432 2.22818424177598e-15 1187.40144164625 156.423470829702 7.59094166206667 5.58739204415245e-13 -975.873971729422 520.615258842186 -1.87446286899024 0.0619792981370931 APMAP other 2.97507159961929e-11 1 7.9162170481552e-09 7.59094166206667 -1.87446286899024 0.141990646676969 8.83039879222718 10.9356973111637 0.807483833994992 0.420109252449176 -25.121907128034 19.3875793274746 -1.29577327337783 0.196176862683877 CELF4 other 1 1 1 0.807483833994992 -1.29577327337783 4.12756876726139e-13 219.639405750018 46.7124069523506 4.7019500830703 4.14219668166497e-06 -211.086440293078 71.7849592276655 -2.9405385552093 0.00356463629700708 ZNF516 other 5.15698441781638e-09 1 0.043865862858832 4.7019500830703 -2.9405385552093 2.53583084624592e-10 262.308026369406 48.7242849155227 5.38351720962536 1.68232442066373e-07 -69.2773960304478 73.6885924955573 -0.940137322267683 0.348054604656271 ADNP2 other 2.8294800582412e-06 1 0.00196293613403044 5.38351720962536 -0.940137322267683 2.19783063090999e-13 118.534570352419 22.8102907483226 5.1965392138255 4.19505657733027e-07 -89.4499255452716 34.3572823830911 -2.60352156343117 0.00977451089481671 RBFA other 2.77190399170368e-09 1 0.00477061833973998 5.1965392138255 -2.60352156343117 2.37186544462858e-18 730.538214757901 88.9322720529986 8.21454571994452 1.18228840548734e-14 -325.953539313438 195.483682104088 -1.66742070644996 0.0966930043937195 USP14 other 3.38156856440696e-14 1 1.72105723186792e-10 8.21454571994452 -1.66742070644996 4.92448739710798e-21 925.127831260493 108.522780480014 8.52473395142017 1.16499336465465e-15 -545.164112166251 240.441242213549 -2.26734859272629 0.0241716190915543 VAPA other 7.29464318133606e-17 1 1.71801571485621e-11 8.52473395142017 -2.26734859272629 3.15394255968999e-12 97.4675448431503 15.5711129965435 6.25951047075353 1.60117055880509e-09 -53.0647105508957 33.4830868682454 -1.5848213385971 0.114231853152588 METTL4 other 3.81122418912939e-08 1 2.05334112461165e-05 6.25951047075353 -1.5848213385971 0.00124699928922068 193.184748881667 78.0906100493343 2.47385375475517 0.0139982462181175 -263.950472759243 168.676689109461 -1.56483076679288 0.118825011292002 LPIN2 other 1 1 1 2.47385375475517 -1.56483076679288 1.7088080899186e-16 502.160930116361 65.3947011866022 7.67892384252139 3.26112915001958e-13 -216.230308830718 141.344020214002 -1.52981575381353 0.127278059609395 SMCHD1 other 2.34465558017731e-12 1 4.64613070003289e-09 7.67892384252139 -1.52981575381353 0.208300714250423 5.33023762939468 6.59590532971708 0.808113119116478 0.419755803222241 -16.2151524293017 14.2472375615103 -1.13812606544218 0.256103563167669 MYOM1 other 1 1 1 0.808113119116478 -1.13812606544218 6.03090844245153e-06 741.766708182139 259.024199562213 2.86369655590416 0.00452481868067199 -1491.11218658691 559.495493168514 -2.66510133646029 0.00817256266352278 MYL12A other 0.050273652776276 1 1 2.86369655590416 -2.66510133646029 3.99513611167051e-15 99.2574085049637 12.9280818403525 7.67765935663797 3.61104538213927e-13 -22.1676915098535 29.3415265927861 -0.755505731433337 0.450653977825605 CEP76 other 5.3035431882426e-11 1 5.14032310147524e-09 7.67765935663797 -0.755505731433337 6.41348443716551e-09 214.755297081049 42.7680689983864 5.02139334579617 9.73723247285979e-07 -158.986590606016 97.0662507659412 -1.637918322295 0.102691701567087 CEP192 essential 6.61294380316135e-05 1 0.0108073543216271 5.02139334579617 -1.637918322295 1.76267187891546e-12 378.561684651404 55.392151776056 6.83421157173827 6.30976683201581e-11 -90.8300733523987 125.941411086323 -0.72120895398053 0.471457575626881 RNMT essential 2.15292743290735e-08 1 8.49357713257649e-07 6.83421157173827 -0.72120895398053 0.000750195747746255 46.7272337719011 46.2913735482397 1.00941558200271 0.313682467630385 -202.076750016249 73.9415019793743 -2.7329273088423 0.00669347836727102 SMAD7 other 1 1 1 1.00941558200271 -2.7329273088423 0.0670061870753141 102.05279895058 49.8858860087633 2.04572489566793 0.0417523650038217 5.53898201135978 78.9319380412496 0.0701741544527278 0.944106991688268 LIPG other 1 1 1 2.04572489566793 0.0701741544527278 0.336170324198964 200.411440649503 147.552798836983 1.35823543998591 0.17552701798363 1.56403471214472 324.218217877325 0.00482401859582273 0.996154580488218 LAMA1 other 1 1 1 1.35823543998591 0.00482401859582273 0.00210264847843033 18.9877589294311 11.9360075953253 1.59079648515535 0.112838661032732 -50.4837331279485 23.2468168865512 -2.17164067555221 0.030763276644712 RNF125 other 1 1 1 1.59079648515535 -2.17164067555221 1.50490595053838e-09 190.85505554675 37.454754454967 5.09561625283703 6.58444229371782e-07 -147.948095490789 82.4570851254296 -1.79424357853225 0.0739055480495722 ANKRD12 other 1.61100182005133e-05 1 0.00739235336315699 5.09561625283703 -1.79424357853225 0.589796762681707 0.127735162333392 36.1227389138861 0.0035361427780408 0.997181212718407 -60.3240578281107 65.0461096681218 -0.927404546342526 0.354554098929361 NOL4 other 1 1 1 0.0035361427780408 -0.927404546342526 2.75426918317641e-19 102.924787604821 21.4398003980915 4.80064112975525 2.62729148274816e-06 -171.780975558725 35.6257659764077 -4.82181844658392 2.38309518879497e-06 POLI other 3.98487665421964e-15 0.0371047920895377 0.0282775382288185 4.80064112975525 -4.82181844658392 3.99802118464481e-12 557.857547212626 90.7939514954073 6.14421487361793 3.52647366712173e-09 -392.408024144247 204.161614156605 -1.92204605045513 0.0558408791741801 MIB1 other 4.81241809995695e-08 1 4.46486830994282e-05 6.14421487361793 -1.92204605045513 6.43637328579109e-15 956.414455818279 125.898265596375 7.59672463546484 6.84654287301547e-13 -238.552489808562 290.483656886158 -0.821225167590244 0.412336429352259 RIOK3 other 8.49022000128702e-11 1 9.67827300529467e-09 7.59672463546484 -0.821225167590244 0.00082375695939768 63.4579676707054 32.0086589899728 1.98252503144804 0.0484265568957768 -191.199746159363 73.3578228161878 -2.6063988654414 0.0096544346110004 EEA1 other 1 1 1 1.98252503144804 -2.6063988654414 0.876739710615848 -3.54526031421573 16.1936819199013 -0.218928612513919 0.826869240251937 7.47110915375412 25.4757767227941 0.293263252973537 0.769543740513167 RUBCNL other 1 1 1 -0.218928612513919 0.293263252973537 0.0543632791965912 3.68861647433734 11.4623187016564 0.321803691761274 0.747850415521483 -41.9000572630742 20.7913064631855 -2.01526812840094 0.0448674459017609 NALCN other 1 1 1 0.321803691761274 -2.01526812840094 0.369303012506872 6.97830957604125 57.2330857309506 0.121927893401482 0.903046822329016 -127.267835776957 104.618384691041 -1.21649589747351 0.224858437361299 FGF14 other 1 1 1 0.121927893401482 -1.21649589747351 3.38682819683407e-09 411.808323489169 97.2414109299115 4.23490691415396 3.22831888210306e-05 -400.956024203899 165.848360524236 -2.41760619723043 0.0163477515978396 NDFIP2 other 3.54668648772464e-05 1 0.317431705170535 4.23490691415396 -2.41760619723043 0.647636735877359 -6.6351366771155 28.6576105524574 -0.231531399485312 0.817079333774322 38.0427492555821 52.4756502522422 0.72496003522999 0.469111398990685 TNFSF13B other 1 1 1 -0.231531399485312 0.72496003522999 4.92790873234958e-05 152.19233581805 74.4806051352026 2.04338210654679 0.0419745776191835 -301.912168561173 119.811462111358 -2.51989386692037 0.0123098985747511 FNDC3A other 0.377576367072625 1 1 2.04338210654679 -2.51989386692037 4.68658129322619e-16 43.4972517460552 6.39735727247118 6.79925317493689 6.61077438071769e-11 -18.0617916577755 10.2909573179774 -1.75511287236835 0.0803616727733187 CDADC1 other 6.36484605433048e-12 1 8.89083046462722e-07 6.79925317493689 -1.75511287236835 0.00593762460099433 46.9959252714686 41.2722922092406 1.13867979595634 0.255834953296474 -137.644287827602 66.3916957347486 -2.07321542708482 0.0390902017049183 CAB39L other 1 1 1 1.13867979595634 -2.07321542708482 0.00869039749106017 1087.06774769691 478.112221998303 2.27366651108276 0.0238311710747445 -873.47805917123 975.478537050819 -0.895435446290834 0.371412264888258 KLF5 other 1 1 1 2.27366651108276 -0.895435446290834 7.88315006156711e-25 1528.96672194401 172.774522337512 8.84949181892222 1.21927452195683e-16 -884.514493734407 310.865168409542 -2.84533162161521 0.00477905291425137 STK24 other 1.20557013891546e-20 1 1.81940144166399e-12 8.84949181892222 -2.84533162161521 0.649168532924762 -113.190704573367 161.993121320321 -0.698737722014423 0.48531515753101 -301.911332338236 346.147145993594 -0.872205175841094 0.383868550146527 ACP5 other 1 1 1 -0.698737722014423 -0.872205175841094 2.03513360862351e-09 231.998890278486 81.7420470019688 2.83818302559634 0.0048936371704652 -529.534962099196 142.374454987126 -3.7193116008562 0.000244554439879695 DNAJC3 other 2.16232945916248e-05 1 1 2.83818302559634 -3.7193116008562 5.3237312190658e-15 120.695051170491 21.1786468962102 5.69890285068633 3.2500116349864e-08 -102.605517488389 36.8879716107438 -2.78154403747439 0.00580464077751128 UGGT2 other 7.04169928345833e-11 1 0.000393543908880503 5.69890285068633 -2.78154403747439 1.19476832210068e-26 469.083494531634 48.4450023841901 9.68280465364819 3.5147807745293e-19 -260.740292256466 95.6274201718978 -2.72662685857011 0.00682548487721807 ARHGEF7 other 1.84543915031671e-22 1 5.35547146615029e-15 9.68280465364819 -2.72662685857011 0.0517047373242774 6.90133369102818 9.45283888327684 0.730080537312175 0.465990750339526 -21.392722186027 14.3898083316094 -1.48665789654992 0.138303008125968 FGF9 other 1 1 1 0.730080537312175 -1.48665789654992 6.24446025720423e-06 62.6860001358689 12.5285841253056 5.00343849783104 1.01844313572414e-06 51.3227082047771 19.1289524113037 2.68298582699434 0.00774884215445735 SGCG other 0.0519726427207108 1 0.0112894421595021 5.00343849783104 2.68298582699434 1.44942805284465e-06 282.412499613005 99.8032858119212 2.82969140059387 0.0050064675610732 -333.623286911387 159.443250694048 -2.09242652454176 0.0373272286032867 PARP4 other 0.0127404725845045 1 1 2.82969140059387 -2.09242652454176 1.03523165401275e-18 191.407393161914 38.3973502082137 4.98491151404947 1.10518236522794e-06 -291.487105401986 59.8349228563977 -4.87152137058065 1.88240359093564e-06 SUPT20H other 1.48379752969648e-14 0.0293447895790958 0.0122144755004992 4.98491151404947 -4.87152137058065 1.72092910018082e-23 88.8857251870153 12.1998365193817 7.28581280952442 3.44164989701918e-12 -74.14861391061 19.3908402692998 -3.82389895852035 0.000162796599805976 MRPS31 essential 2.60927270169416e-19 1 4.79112082164039e-08 7.28581280952442 -3.82389895852035 1.41986779075294e-11 56.5494390509922 9.41797890223644 6.00441343498483 6.10208051760946e-09 -11.0169049078059 14.9692599784245 -0.735968573174948 0.462381697940846 SLC25A15 other 1.67572796664662e-07 1 7.64529668051289e-05 6.00441343498483 -0.735968573174948 1.59742989857954e-16 378.647361556332 58.1531287664773 6.51121220109838 3.56405529171223e-10 -221.504284518908 93.5466538062352 -2.36784829287121 0.0185890233920709 KPNA3 other 2.19375047971928e-12 1 4.67639694825561e-06 6.51121220109838 -2.36784829287121 0.308267927818125 -58.5887407830115 82.2965295390743 -0.711922375234471 0.477125256546274 99.7457679291871 129.673751140616 0.769205541228034 0.442441185684354 FLT1 other 1 1 1 -0.711922375234471 0.769205541228034 0.790544533711681 104.594156340026 255.317679352682 0.409662803630394 0.682375754789488 276.252828259323 405.582702417876 0.68112576451719 0.496371371817218 RGCC other 1 1 1 0.409662803630394 0.68112576451719 2.70916802969308e-10 117.066927113207 56.8960867551378 2.05755674580969 0.0405857959608216 -424.603782811184 90.3817889997137 -4.69789088610017 4.17726429041708e-06 DGKH other 3.01828410188106e-06 0.0647517737657551 1 2.05755674580969 -4.69789088610017 0.00086705917221447 13.4673183900524 17.4540847846691 0.77158548020126 0.441037241196476 -76.0347306016851 27.6457995685858 -2.75031765361144 0.00635766653104725 KATNAL1 other 1 1 1 0.77158548020126 -2.75031765361144 3.06643527174206e-18 176.092043575159 34.3919543966739 5.1201522758529 5.7847059984362e-07 -267.779076221521 56.319225129104 -4.75466549136062 3.22674843805096e-06 INTS6 other 4.36476396579765e-14 0.0501243102366837 0.00651473589543884 5.1201522758529 -4.75466549136062 9.7967253254136e-10 49.5044754303861 13.5016576907597 3.66654795760864 0.000295626258694375 -70.243986378316 22.0556464303889 -3.18485275868096 0.001616817693969 DHRS12 other 1.05853617141094e-05 1 1 3.66654795760864 -3.18485275868096 0.0882010153446677 -53.4866090285022 29.2462250257187 -1.828838045986 0.0685309840075988 -90.3354217127761 44.6766487737063 -2.02198294170044 0.0441679007003361 MEDAG other 1 1 1 -1.828838045986 -2.02198294170044 0.000297889635017065 539.755132237783 377.073251851156 1.43143309579233 0.153449914227375 -1554.58261807152 596.335658578547 -2.60689193360849 0.00963902241195286 TSC22D1 other 1 1 1 1.43143309579233 -2.60689193360849 1.57711679549347e-10 197.086766982968 38.64690006352 5.09967854236785 6.72610384956088e-07 -167.304684956525 78.3270650376312 -2.13597541125977 0.0336531413663317 CLN5 other 1.7763066467643e-06 1 0.00754803373997722 5.09967854236785 -2.13597541125977 0.411691181316579 -204.42048055549 355.203655416926 -0.575502187091932 0.565431025104824 -784.706113802121 589.482386683272 -1.33117821928027 0.184253282799775 OLFM4 other 1 1 1 -0.575502187091932 -1.33117821928027 0.0429503307828823 -426.708219500037 303.446190274163 -1.4062072063403 0.160808185427189 -1401.81467683377 555.461018899312 -2.52369586548408 0.012184870024102 MSLN other 1 1 1 -1.4062072063403 -2.52369586548408 1.29648048315957e-10 193.474630872483 59.6453432652296 3.24375081575345 0.00132698436558104 -433.689981696156 116.395493326449 -3.72600320941815 0.000236582703536292 MGRN1 other 1.46644907450179e-06 1 1 3.24375081575345 -3.72600320941815 7.5198128153283e-10 226.570748967224 45.9642063890737 4.92928665077709 1.45097493006465e-06 -152.92492265529 95.6806823391786 -1.59828419819568 0.111162450004218 ZNF629 other 8.18531624948485e-06 1 0.0159055871833687 4.92928665077709 -1.59828419819568 2.92637794592281e-08 98.9267093853771 28.3385815810194 3.49088429505717 0.000562469560916462 -110.190467697691 49.4075402395635 -2.23023585394877 0.0265569340909157 TRADD other 0.000290062581999869 1 1 3.49088429505717 -2.23023585394877 0.372008427398659 39.4379593535292 42.4687765456368 0.928634224043383 0.353911197719769 -27.4785463748547 74.0431478584998 -0.371115318157025 0.710843748722968 HSF4 other 1 1 1 0.928634224043383 -0.371115318157025 0.0226247051027506 -326.290574324844 120.357777088165 -2.71100532278715 0.00714288781181053 -440.930861410121 240.105414898422 -1.83640532054081 0.0674094328127041 CORO1A other 1 1 1 -2.71100532278715 -1.83640532054081 2.86104857814018e-06 128.973090369743 66.2682102922736 1.94622866380292 0.0526762266084879 -425.387836254663 132.36037926587 -3.21386081404461 0.00147049719816769 MAPK3 other 0.0245106031689269 1 1 1.94622866380292 -3.21386081404461 0.00123715426414749 10.1539541544597 9.05629908339647 1.12120349173048 0.263208639807229 -46.0012220069409 18.1155493312548 -2.53932249946044 0.0116745854736429 GDPD3 other 1 1 1 1.12120349173048 -2.53932249946044 1.32189700638282e-10 222.942767341198 59.1827126542779 3.7670251555305 0.000202831966554723 -297.548179505036 103.069879314295 -2.8868587164802 0.00420575902732244 ELMO3 other 1.49427237601514e-06 1 1 3.7670251555305 -2.8868587164802 1.63019917463943e-17 304.662274647591 73.1260795937175 4.16626019527191 4.21301007080074e-05 -600.444386854135 129.047821266396 -4.65288279152445 5.20956603346327e-06 PHKB other 2.28945172086362e-13 0.0805971961037102 0.410010140090328 4.16626019527191 -4.65288279152445 4.16260051753267e-05 124.954072918255 44.4856729588212 2.80886102440037 0.00533488215284128 -151.61313523229 87.1220193995041 -1.74023899213191 0.0829564140910527 LYRM1 other 0.321394385958697 1 1 2.80886102440037 -1.74023899213191 3.20021577112346e-19 614.826628236518 91.064401310391 6.75155845082531 8.92661160056564e-11 -407.146489859778 164.079951525306 -2.48139084680912 0.0136960965036159 NUTF2 essential 4.62623191873607e-15 1 1.1947376966197e-06 6.75155845082531 -2.48139084680912 1.85982741213369e-13 454.71697948367 94.2576529450774 4.82419162026692 2.34443496493439e-06 -399.895569113386 169.319898886279 -2.3617753834236 0.0188925401342485 NUP93 essential 2.35156577990183e-09 1 0.0253105198814316 4.82419162026692 -2.3617753834236 1.84630649368225e-07 183.187064070751 46.4627196279429 3.9426677030025 0.000102733746969004 -110.66895178717 83.7165860049073 -1.32194774140316 0.187304432079183 CENPT essential 0.00173755904120437 1 0.962409741605633 3.9426677030025 -1.32194774140316 0.000675995224553638 17.8551753943615 6.88345738535892 2.59392546430801 0.0100066700730559 -12.2227706459188 12.4026220769468 -0.985498918703463 0.325261351929912 TSNAXIP1 other 1 1 1 2.59392546430801 -0.985498918703463 3.22643461112043e-06 143.861038773275 65.9074940561792 2.18277209342307 0.0299077936123063 -347.646912134946 121.55928780776 -2.85989592736619 0.00456626376362186 NFAT5 other 0.0275182607982462 1 1 2.18277209342307 -2.85989592736619 2.87326801585313e-29 333.08234276455 67.165592064175 4.95912166524637 1.27426315629355e-06 -846.400321097252 118.386784323201 -7.14944937423543 8.67408057577107e-12 LONP2 other 4.48861929436576e-25 1.38386281505852e-07 0.0140258145613231 4.95912166524637 -7.14944937423543 9.9492294336721e-10 13.1005784353137 72.4881358441258 0.180727208428762 0.856721420067983 -692.23078391319 127.768356392509 -5.41785778152011 1.36652853366145e-07 N4BP1 other 1.07471576342526e-05 0.00215761190179807 1 0.180727208428762 -5.41785778152011 3.60672456070923e-14 294.074117818531 79.1950451358015 3.71328935180554 0.000248016306775658 -530.681587901513 139.015935388364 -3.81741551009219 0.000166909016301274 ARL2BP other 4.66169149471667e-10 1 1 3.71328935180554 -3.81741551009219 2.75721009416741e-10 251.171772203429 105.445499008316 2.38200562912241 0.0179038360807125 -706.99149859022 185.094972191727 -3.81961481837494 0.000165503116998733 PLLP other 3.07042916086483e-06 1 1 2.38200562912241 -3.81961481837494 0.348189908303716 21.2867196127826 21.2063079928306 1.00379187268143 0.316387775450405 -10.823630845232 37.9827702527254 -0.284961596355794 0.775894472620995 ZNF423 other 1 1 1 1.00379187268143 -0.284961596355794 0.453052236116127 -18.6692014253619 19.4744687258721 -0.958650101738569 0.338583262112031 -41.9353938090235 34.1847331670335 -1.22672871553856 0.220981498733119 CCL22 other 1 1 1 -0.958650101738569 -1.22672871553856 6.6435813082577e-18 74.4990828345239 12.6033977322541 5.91103164536882 1.02678393895846e-08 -67.1212796182388 21.6221690635352 -3.10428058447826 0.00211099160232354 DHODH essential 9.39801011866134e-14 1 0.000127423886824745 5.91103164536882 -3.10428058447826 0.488934892611524 -2.6406087441636 4.20978945423471 -0.627254349147403 0.531016769285874 -8.82169069912765 7.38970244621965 -1.19378158502722 0.233599719281116 CCL17 other 1 1 1 -0.627254349147403 -1.19378158502722 6.79116876579792e-12 148.171522429277 48.1817861720794 3.07526005574155 0.00231895055324055 -339.568965603077 84.9507013700087 -3.99724734612915 8.2745886387631e-05 CTCF other 8.10118522072034e-08 1 1 3.07526005574155 -3.99724734612915 4.93735064183483e-17 170.32661807585 22.5958046765443 7.53797532391748 7.25645182873326e-13 -13.4723789087981 39.8393170489079 -0.338167918196465 0.735499447406801 ACD other 6.86341112721459e-13 1 1.02519151436344e-08 7.53797532391748 -0.338167918196465 5.55659897626157e-23 587.918415835799 79.6921835106794 7.37736613474787 1.9447500440768e-12 -335.918861144616 139.342831089967 -2.41073658771673 0.0165813637193223 POLR2C essential 8.38824181456446e-19 1 2.72187216168988e-08 7.37736613474787 -2.41073658771673 0.110050522859539 9.80480448336562 13.7386524166153 0.713665662835161 0.476050375462866 -30.334898262978 24.2230156122056 -1.25231716598047 0.211537978237778 PARD6A other 1 1 1 0.713665662835161 -1.25231716598047 7.57801962265256e-08 48.1300444101177 10.2101288415992 4.71395074017297 3.90335311446917e-06 -7.17224781397405 17.5163187470121 -0.409460909998424 0.682527297291434 ZNF821 other 0.000731127333193519 1 0.0414419000163191 4.71395074017297 -0.409460909998424 5.10169596021253e-06 74.4390387134655 68.1033779427019 1.0930300516972 0.275344168071878 -398.623952859215 119.22594480825 -3.34343295413023 0.000943257059432462 MMP15 other 0.0428287375859842 1 1 1.0930300516972 -3.34343295413023 1.44690505645905e-13 271.428151962776 78.3255998430212 3.46538235911079 0.000614735035674659 -535.457253567431 137.121592585524 -3.90498129048101 0.00011882785354751 USB1 other 1.83482030209571e-09 1 1 3.46538235911079 -3.90498129048101 4.55500009604096e-07 425.76250179902 144.705814932217 2.94226256213998 0.00354006763318017 -656.74455773652 261.486065929338 -2.51158529385652 0.0126009302921653 CYB5B other 0.00417329108799273 1 1 2.94226256213998 -2.51158529385652 0.00220945758652835 29.0256583999636 26.696930391807 1.0872283058007 0.277894896505961 -97.3122022958046 46.7372815504282 -2.08211087739041 0.038263620035216 CCDC113 other 1 1 1 1.0872283058007 -2.08211087739041 0.000400809465449636 6.39454307268371 4.01220869650373 1.59377130064445 0.112144343231917 -14.3331325633806 7.02401829481936 -2.04058872881241 0.0422536945382685 PRSS54 other 1 1 1 1.59377130064445 -2.04058872881241 0.000431077316928666 33.2298095273014 43.340434492336 0.766716114329161 0.443920178776365 -221.683502265111 79.4191650085997 -2.79130990915237 0.00562420078183121 NME3 other 1 1 1 0.766716114329161 -2.79130990915237 0.00596205864224152 180.686678411708 184.542088947426 0.979108231852643 0.328393355442881 -618.402011714926 323.070684249413 -1.91413842810175 0.0566478690397757 NDRG4 other 1 1 1 0.979108231852643 -1.91413842810175 3.17506238183644e-27 738.187382113822 97.7745264698655 7.54989472990528 6.66898321657874e-13 -687.14588617886 172.721404692667 -3.97834818100013 8.91275230699211e-05 PSMD7 essential 4.9191241481792e-23 1 9.42860847159902e-09 7.54989472990528 -3.97834818100013 6.32266144239539e-16 117.50133261056 44.8581927180233 2.61939515372741 0.00930122035242887 -421.342212384495 78.5314997693154 -5.36526379379204 1.72628596358226e-07 SETD6 other 8.5583545284264e-12 0.00272356136474373 1 2.61939515372741 -5.36526379379204 1.4040322230983e-13 208.279577178479 40.4529014375012 5.14869316605798 5.02619854293767e-07 -145.86091159597 70.8193270263174 -2.05962013084036 0.0403829436458404 SLC38A7 other 1.78171689111174e-09 1 0.00568060959322816 5.14869316605798 -2.05962013084036 1.58002078067223e-20 233.963206082614 46.3019980971355 5.05298293157435 8.00859249946218e-07 -397.43466572918 79.9714300943684 -4.9697081227658 1.18999691646076e-06 VAC14 other 2.32452657252498e-16 0.0186032217950311 0.00893999180714963 5.05298293157435 -4.9697081227658 0.0039015648467499 924.929256134973 520.456454445376 1.77715013088006 0.0766734591099927 -1436.69599422591 944.348438242856 -1.5213621752784 0.129343559791496 HAS3 other 1 1 1 1.77715013088006 -1.5213621752784 1.3057419494721e-14 62.7134433962268 14.347758729427 4.37095748394503 1.76887857834963e-05 -105.633855900851 26.5025878418314 -3.98579401118406 8.66848202753467e-05 TANGO6 essential 1.70660472796003e-10 1 0.177966873767756 4.37095748394503 -3.98579401118406 6.76794247816156e-25 315.826394094384 49.6580955005281 6.36001825907773 8.49889817624422e-10 -447.684692177499 89.8357268248024 -4.98337029153861 1.11328115563487e-06 COG4 essential 1.03583359628263e-20 0.0174183969610631 1.10077729178715e-05 6.36001825907773 -4.98337029153861 0.423738146533386 -7.7635658694742 23.896952161027 -0.324876821829005 0.745524950226789 -55.2176988074039 43.8398394081198 -1.25953241510225 0.208921777249656 SMPD3 other 1 1 1 -0.324876821829005 -1.25953241510225 1.10003830728923e-15 160.836643372305 34.7137102266416 4.6332311447616 5.59742444974868e-06 -246.713856160092 62.5519161001305 -3.94414546414794 0.000102048471988688 SLC7A6OS essential 1.48043155394984e-11 1 0.0586554108089164 4.6332311447616 -3.94414546414794 2.00614069756928e-11 160.897457210098 47.357421366778 3.39751305215639 0.000782091051393454 -315.932979253313 85.413427903426 -3.69886781280488 0.00026217621396261 SLC7A6 other 2.35199935383022e-07 1 1 3.39751305215639 -3.69886781280488 4.69492897219061e-07 99.1222480363705 30.842763638066 3.21379268082301 0.00146837978765285 -117.272374599381 55.6277367371701 -2.10816368736102 0.0359349363376178 PLA2G15 other 0.00429773798114329 1 1 3.21379268082301 -2.10816368736102 0.0476973548097418 229.441746903564 92.9238112120291 2.46913836088831 0.0141631074547212 256.382392918146 158.003237719201 1.6226401219308 0.105833365693071 FA2H other 1 1 1 2.46913836088831 1.6226401219308 2.32692466099372e-19 216.18533965678 40.1941238079127 5.37853096860445 1.6280583973748e-07 -260.313017846481 68.2579714603184 -3.81366472336222 0.00016971960575261 WDR59 other 3.3717138337799e-15 1 0.0019017350139735 5.37853096860445 -3.81366472336222 3.64498722437202e-20 166.175757269737 43.6463794581948 3.80732054600092 0.000173508352852398 -410.05808879416 72.6531131209088 -5.64405393216591 4.15616425987128e-08 MON1B other 5.33808379009282e-16 0.000658461103691407 1 3.80732054600092 -5.64405393216591 1.44292849303119e-14 258.681937172773 39.4562235138281 6.55617578509798 2.74885490269564e-10 -33.3531299795134 66.0496289613471 -0.504970739487908 0.613986773768111 CMC2 other 1.88359885480292e-10 1 3.61996702135989e-06 6.55617578509798 -0.504970739487908 7.1329233938569e-12 287.884411463988 56.0527130925162 5.1359585572393 5.48418734425976e-07 -178.088329626545 102.285672062962 -1.74108774019613 0.082842046173745 AXIN1 ts 8.50601114717435e-08 1 0.00618451806812173 5.1359585572393 -1.74108774019613 2.77714948372254e-07 166.093546416938 50.3670819442483 3.29766069435565 0.00110520636725046 -189.931256786102 90.8308005276197 -2.09104462013794 0.0374554048014357 HCFC1R1 other 0.00258330444975871 1 1 3.29766069435565 -2.09104462013794 9.72582916109576e-18 287.365327853941 51.6828128610216 5.56017197877145 6.67878720626481e-08 -319.319959760704 94.5266266758516 -3.37809536836333 0.000841761015946345 NPRL3 other 1.37143917000611e-13 1 0.000796445374347079 5.56017197877145 -3.37809536836333 6.73005983127335e-16 56.160039372928 11.3144403061954 4.96357202416602 1.2201567977683e-06 -62.4627895269299 19.4892616159515 -3.2049849172226 0.00151112353060954 MLYCD other 9.09904089188157e-12 1 0.0134485682250022 4.96357202416602 -3.2049849172226 3.38977433424062e-08 158.445292751577 50.2417201125638 3.15365979501874 0.00180166229020686 -234.740535311051 91.8909025598857 -2.55455685787904 0.0112028462786956 MPG other 0.000334197851612782 1 1 3.15365979501874 -2.55455685787904 0.00175512953111107 46.163622019889 15.8778682510298 2.9074193896838 0.00394346835835417 -1.84610943036317 27.3498219862 -0.0674998700647728 0.946233174323256 NECAB2 other 1 1 1 2.9074193896838 -0.0674998700647728 2.62744997825389e-12 205.683638041364 40.6045630948534 5.06553013662236 7.50939638558581e-07 -124.009305731078 70.0412599978405 -1.77051791665229 0.0777568443627432 HSDL1 other 3.18683407862414e-08 1 0.00839550515908493 5.06553013662236 -1.77051791665229 3.16349589710791e-08 221.256101711065 66.3552656154643 3.33441663836096 0.000973122551520512 -250.474521387717 114.625781811599 -2.18514994994234 0.0297279699915468 TAF1C essential 0.00031280647430603 1 1 3.33441663836096 -2.18514994994234 2.02512962480309e-15 87.0492860794846 12.9270293969203 6.73389712413146 9.73094229220868e-11 -37.4776821040586 25.2684750043413 -1.4831794201122 0.13918025524689 NAGPA other 2.70780082132421e-11 1 1.30112429389122e-06 6.73389712413146 -1.4831794201122 0.0969429762434368 -28.1362046200128 12.9700085103096 -2.16932815407545 0.0309207299514123 -27.5810784300381 22.405115130017 -1.23101703651086 0.21937598015694 WFDC1 other 1 1 1 -2.16932815407545 -1.23101703651086 0.345107891334716 -1.46121032921375 11.1310287519438 -0.131273610173596 0.895655554784609 -28.8468734418527 21.7578310650476 -1.3258156732448 0.186009043008047 SEC14L5 other 1 1 1 -0.131273610173596 -1.3258156732448 0.000457516488196691 107.259251456082 244.18255710084 0.439258449618854 0.66082175478448 -1198.69615454933 407.344461344219 -2.94270885774091 0.00353302210389941 COTL1 other 1 1 1 0.439258449618854 -2.94270885774091 3.98739059089066e-25 554.977345185131 71.882704120987 7.72059637949957 2.19927246777071e-13 -321.685989396064 119.914467838246 -2.68262867021176 0.00775018820072488 USP10 essential 6.11147355865812e-21 1 3.14100093847013e-09 7.72059637949957 -2.68262867021176 0.401952254036658 -207.051906946058 165.665673912422 -1.2498177930059 0.212436477582407 -317.151774650149 275.93842139698 -1.1493570668576 0.251414709394656 CRISPLD2 other 1 1 1 -1.2498177930059 -1.1493570668576 2.33774279855781e-11 377.511189848836 83.5335406668458 4.5192767699678 9.27713174324487e-06 -334.412293525541 152.906570538501 -2.18703677904631 0.0295947029703558 TSC2 ts 2.7316524601148e-07 1 0.0955359026919357 4.5192767699678 -2.18703677904631 8.44227332497209e-17 83.889322617681 12.3588482891482 6.78779451410056 7.07569349120773e-11 -48.0642939150403 23.9671546336994 -2.00542344928416 0.0459046118615535 ZNF500 other 1.16773524631014e-12 1 9.4998260812955e-07 6.78779451410056 -2.00542344928416 1.25932483097036e-05 505.742238937747 127.327494673647 3.97197981656685 9.20775646000766e-05 -25.1200891766634 232.278743194148 -0.108146310898828 0.91396209158685 NME4 other 0.102231989778174 1 0.866910270709722 3.97197981656685 -0.108146310898828 0.0943474221282677 1424.43169232694 906.808694812907 1.57081829990705 0.117400327005492 -903.579382902755 1827.34106691496 -0.494477686329371 0.621372440283221 ABCC1 other 1 1 1 1.57081829990705 -0.494477686329371 7.03027071269704e-15 879.272808827487 121.043618556505 7.26409883737101 4.09432464088534e-12 -59.4843904189474 245.519652493081 -0.242279547950337 0.808748860283402 NOMO3 other 9.258866528622e-11 1 5.6886546560461e-08 7.26409883737101 -0.242279547950337 9.602262220722e-05 -19.5193521318245 9.54166860273801 -2.04569587820556 0.041748103347054 -75.9062443646273 17.447251581651 -4.35061327621691 1.92217612349142e-05 LMF1 other 0.71325603775523 0.293727733430724 1 -2.04569587820556 -4.35061327621691 0.455471797049037 -35.3875350306452 33.8748127265097 -1.04465625585442 0.297105982604924 -66.4132183466234 56.4883714072342 -1.17569716903041 0.240740193761785 FOXF1 other 1 1 1 -1.04465625585442 -1.17569716903041 2.42864666833531e-16 147.354247425262 29.429696152449 5.00699180385523 9.97269861713616e-07 -186.740536123141 53.8713272226847 -3.46641795831803 0.000613129412358332 NARFL essential 3.32093145428171e-12 1 0.0110637118458509 5.00699180385523 -3.46641795831803 2.53807584999759e-16 86.372317229137 16.715675763823 5.16714480763432 4.59473433061068e-07 -84.5617155232057 27.8744360446544 -3.0336655201827 0.00264875489222252 MTHFSD other 3.46980349453171e-12 1 0.00520950978404638 5.16714480763432 -3.0336655201827 7.8176655206331e-09 287.324461358452 82.5326420064821 3.48134331306013 0.000581027209938212 -367.087719090898 150.913622002364 -2.43243594726756 0.0156428759337196 CLCN7 other 8.01936129106544e-05 1 1 3.48134331306013 -2.43243594726756 0.000176516801453704 38.7720370636348 17.2283779641744 2.25047518369167 0.0252208363208939 -53.6692710393501 31.5367029960619 -1.70180348421495 0.0899390624826804 HAGHL other 1 1 1 2.25047518369167 -1.70180348421495 6.55655615767177e-05 4.20291218662084 10.433252424067 0.402838157823703 0.687384890418103 -66.1047760444308 19.0981637194719 -3.46131581106054 0.000624362649994682 FAM173A other 0.496396866697329 1 1 0.402838157823703 -3.46131581106054 4.9807833233511e-11 5400.14680770341 867.973701335814 6.22155579067957 1.84324475461263e-09 972.433220118515 1416.63467299382 0.686438951874189 0.493018952395693 SLC7A5 essential 5.74732587681483e-07 1 2.35861598800231e-05 6.22155579067957 0.686438951874189 0.013248503856902 4.20305312613057 29.5467732204738 0.142250833780325 0.886987578703535 -128.367732686522 54.0856378635138 -2.37341626644878 0.0183219820886816 METRN other 1 1 1 0.142250833780325 -2.37341626644878 2.13371081316931e-12 41.9735012470003 16.1070496590869 2.60590872539595 0.00966604669791728 -116.961844932787 26.9003524551317 -4.34796700630123 1.94161387876962e-05 FBXO31 other 2.59800628611495e-08 0.296620352259635 1 2.60590872539595 -4.34796700630123 1.13049945137982e-21 455.864012190691 88.694877390111 5.13968817145597 5.27439463376309e-07 -804.851431323287 162.356782010505 -4.9573009600006 1.26177978985182e-06 STUB1 other 1.68591383184272e-17 0.0197178327760144 0.00595479154151853 5.13968817145597 -4.9573009600006 0.0539030968123425 0.350830698238188 13.4241086316384 0.0261343756866909 0.979169392592432 -49.1069523501567 24.5729532857471 -1.99841475215109 0.0466706719614267 RHBDL1 other 1 1 1 0.0261343756866909 -1.99841475215109 1.3324897990917e-14 87.4913992628845 15.2689036187636 5.73003808573188 2.6951992552901e-08 -77.079764045235 29.7433954730088 -2.59149175201542 0.0100798786625455 NUBP1 essential 1.7408979225133e-10 1 0.000327763181435829 5.73003808573188 -2.59149175201542 1.31809941169359e-28 719.488665966942 82.4691083497126 8.72434151847416 2.72972151830431e-16 -436.991352073876 150.797448643205 -2.89786966560569 0.00406293338379725 UBE2I essential 2.05293983371276e-24 1 4.05964184202218e-12 8.72434151847416 -2.89786966560569 0.0681985360497947 -12.1864368904901 5.25707976883033 -2.31810005295041 0.0211858354482429 -13.2682725517939 9.42526008059153 -1.40773542993428 0.160351234101318 MEFV other 1 1 1 -2.31810005295041 -1.40773542993428 0.316970482119835 -19.6051989674691 39.4956318334059 -0.496389045000332 0.620022333906263 -116.212954001847 77.8706169256865 -1.49238517158214 0.136761414695145 CRYM other 1 1 1 -0.496389045000332 -1.49238517158214 1.36436363135724e-06 160.063418601734 66.3667518570279 2.41180130295595 0.0165515548786793 -313.715347459909 121.006264131634 -2.59255460625279 0.0100535362901214 CAPN15 other 0.0120214079558887 1 1 2.41180130295595 -2.59255460625279 2.29219256676424e-19 901.653486456147 125.571403238182 7.18040463994742 6.85430574546271e-12 -628.406789430481 245.0321428959 -2.56458920859805 0.0108750508550824 GSPT1 essential 3.32161624849805e-15 1 9.46373994276037e-08 7.18040463994742 -2.56458920859805 2.8860702468596e-15 60.7156690468292 10.1911365846152 5.95769358429433 7.86334607755346e-09 -41.2093997318782 18.2677473755 -2.25585557347627 0.024871313966089 ZNF174 other 3.84222531964419e-11 1 9.80559255870916e-05 5.95769358429433 -2.25585557347627 0.00550814875923693 88.7055531583437 33.9941845074631 2.60943318522229 0.009571347269045 -17.6079890722267 60.9471501859564 -0.288905863826328 0.772873478213576 CLUAP1 other 1 1 1 2.60943318522229 -0.288905863826328 5.9455628028616e-18 502.790444498321 61.7994596800135 8.13583884230832 1.47003829089594e-14 -104.042333355187 129.396106399758 -0.804060773156165 0.422064042153949 UBFD1 other 8.41713326001116e-14 1 2.13655365198817e-10 8.13583884230832 -0.804060773156165 1.37206228492067e-24 285.57011237584 29.7156963595311 9.61007640274417 5.15205464579059e-19 -89.433657880617 62.2189162783944 -1.43740301551464 0.15175288735739 EARS2 essential 2.09596234644481e-20 1 7.84194237635786e-15 9.61007640274417 -1.43740301551464 8.04930133060396e-09 434.51280899614 118.844769404483 3.65613742340897 0.000307497586966597 -520.16052728179 219.959716468541 -2.36479904426584 0.0187447818378185 ELOB other 8.249728933736e-05 1 1 3.65613742340897 -2.36479904426584 2.61398690892667e-05 101.250057490341 103.298793070278 0.980166897220727 0.327874735284107 -783.979100570118 216.287677728858 -3.62470534060164 0.0003452210226186 GGA2 other 0.206112867768868 1 1 0.980166897220727 -3.62470534060164 0.00852595342422802 32.2601000108182 35.2501563571806 0.91517608273663 0.360921890110224 -151.279324265078 70.7140314697658 -2.13931126709638 0.0333140362796177 CPPED1 other 1 1 1 0.91517608273663 -2.13931126709638 0.000276864202241885 166.617468599733 82.7313918429608 2.01395703478558 0.0449985483806614 -335.164529100226 158.308858933454 -2.11715586454397 0.0351543346316772 USP31 other 1 1 1 2.01395703478558 -2.11715586454397 4.83632936316536e-16 308.667608618863 49.634805827401 6.21877336827342 1.8804241909148e-09 -232.541151536559 96.8603313213002 -2.40078831410544 0.01703165601483 HMOX2 other 6.56725164224225e-12 1 2.40543862501822e-05 6.21877336827342 -2.40078831410544 6.3835868750443e-29 654.52739415893 60.1901619499563 10.8743251879455 4.15474739400205e-23 -54.5874394385341 116.352424940334 -0.469156009997444 0.639333954738675 DNAJA3 essential 9.9558420903191e-25 1 6.45481555132158e-19 10.8743251879455 -0.469156009997444 4.05209036685614e-10 139.591691193117 30.8245520173313 4.5285878320188 8.89257324730294e-06 -126.970142630745 59.5863386760427 -2.13085994964472 0.033997620937752 CORO7-PAM16 other 4.47634422826598e-06 1 0.0916557524599514 4.5285878320188 -2.13085994964472 5.27503997663189e-26 351.837605028983 43.836931007689 8.02605467447689 3.07153957903871e-14 -307.321484705062 85.5767042983313 -3.59118158644787 0.000390735250068973 BFAR other 8.1267265879991e-22 1 4.44236769316368e-10 8.02605467447689 -3.59118158644787 0.273186214782515 21.6653509875971 18.6598916641056 1.1610652075367 0.246644659712575 -8.2631900266106 33.3739200953632 -0.247594229356312 0.804637255077612 SALL1 other 1 1 1 1.1610652075367 -0.247594229356312 0.0944035591880964 47.368813963198 35.3578746215527 1.33969630443579 0.18147058577107 -39.7361902667612 63.4431997692978 -0.626327020252072 0.531629617578512 TOX3 other 1 1 1 1.33969630443579 -0.626327020252072 1.07573739181494e-06 12.0845963877627 5.1648121813648 2.33979396799079 0.0200428268211636 -32.0405307777368 10.4168907600127 -3.07582478456343 0.00232060668738764 RRN3P2 other 0.00955469951410029 1 1 2.33979396799079 -3.07582478456343 1.88930171706305e-11 193.120609499202 83.2275341202771 2.32039326336536 0.0210596185556192 -646.145264400586 149.125254219238 -4.33290302023993 2.07266586302331e-05 RBL2 ts 2.21804021583203e-07 0.316371717331877 1 2.32039326336536 -4.33290302023993 0.0542864018164941 78.9365910118865 47.2385294379298 1.67102134531108 0.0958760968110535 -63.9032500934091 95.671168568741 -0.667946791592639 0.504738110718892 XYLT1 other 1 1 1 1.67102134531108 -0.667946791592639 0.329060729800649 -13.7304049353374 62.8351702586253 -0.218514645203061 0.827196334963038 -181.234315148479 129.820434933804 -1.39603842215512 0.163871333064967 PYCARD other 1 1 1 -0.218514645203061 -1.39603842215512 2.33002964976163e-11 62.8443461809779 12.9847326714174 4.83986446015279 2.17656141831143e-06 -38.1111955268908 23.2601529716975 -1.63847570449188 0.102474446180548 RPGRIP1L other 2.72310565167642e-07 1 0.0235416883004564 4.83986446015279 -1.63847570449188 4.43711402194202e-11 1018.62245754026 249.09964493056 4.08921681853147 5.74501751465039e-05 -1563.13388579773 494.157154733859 -3.16323232563453 0.00174199066933944 MAZ other 5.12886009796278e-07 1 0.552325983858489 4.08921681853147 -3.16323232563453 2.32544004092812e-07 114.985599563026 35.8932687775569 3.20354215370108 0.00152281284483491 -186.17009725466 74.5186929091003 -2.49830062749162 0.013083072120799 STX4 other 0.00217428643826779 1 1 3.20354215370108 -2.49830062749162 3.40561553580701e-15 342.292236265698 78.8345471340024 4.34190654617286 2.0122708530936e-05 -690.58202226059 156.389847594246 -4.41577271724383 1.46715464345332e-05 CDIPT essential 4.52674417019467e-11 0.224914806841393 0.201367944269077 4.34190654617286 -4.41577271724383 4.40985053765599e-18 292.075806116969 41.9950373147179 6.95500765788356 2.73034862935139e-11 -205.157422663217 86.6650161259695 -2.36724611422233 0.0186371496910286 BCKDK other 6.25757791293385e-14 1 3.71054378728854e-07 6.95500765788356 -2.36724611422233 7.91752471444814e-19 173.695503197618 27.4972955079067 6.31682134512728 1.11671869293704e-09 -197.523084073749 56.7460755125487 -3.48082369202905 0.000584053237236849 KAT8 essential 1.13751077572476e-14 1 1.44090212949667e-05 6.31682134512728 -3.48082369202905 2.95458500220612e-11 927.650979109713 153.378136407545 6.04813046264189 4.88564994324067e-09 -109.036055410047 300.821085879234 -0.362461478028903 0.717291811204519 NOMO1 other 3.43854602556749e-07 1 6.14712475858542e-05 6.04813046264189 -0.362461478028903 0.233651973677879 -21.1907310371977 16.4255681525866 -1.290106426782 0.1981341096 32.102384738722 51.7007081539132 0.620927369953097 0.535179097653067 IL21R other 1 1 1 -1.290106426782 0.620927369953097 0.0102146773737922 38.0008114615224 31.8011097092605 1.19495237144056 0.23315034909154 -112.060914603335 62.1799720935815 -1.80220271624893 0.0726246344499099 SYT17 other 1 1 1 1.19495237144056 -1.80220271624893 0.00309142567743317 -30.8527769509775 73.4626988129802 -0.419978811689478 0.674834941022668 -450.19262068758 142.924250729832 -3.14986867790949 0.0018170410741287 TMC5 other 1 1 1 -0.419978811689478 -3.14986867790949 2.13424831530854e-08 121.278252651813 34.3540622471044 3.5302448886386 0.000487682501285528 -174.066025830161 67.7807320599385 -2.5680753296709 0.0107628753322401 CCP110 other 0.000213083351800405 1 1 3.5302448886386 -2.5680753296709 1.85456560354562e-14 212.884530794638 44.8857530688169 4.74280849133248 3.41769704465856e-06 -323.62060747361 88.9164252341918 -3.63960434330603 0.000327148044367524 C16orf62 other 2.41334621989392e-10 1 0.0364087266167476 4.74280849133248 -3.63960434330603 0.002692044275972 36.1149266240438 15.1500124561702 2.38382157958789 0.0178175775163816 -17.6793250342376 27.2073628963011 -0.649799287847965 0.516368258846621 SLC6A2 other 1 1 1 2.38382157958789 -0.649799287847965 1.26270052070866e-18 640.999662468291 95.2856743928784 6.72713570589158 1.04957685588455e-10 -584.588547332138 198.349956613776 -2.94725825662992 0.00348941356430745 RNF40 essential 1.80793460555066e-14 1 1.40149997566265e-06 6.72713570589158 -2.94725825662992 6.99017651904468e-22 297.062055566349 33.3694996371435 8.90220287377907 8.19350350183856e-17 -55.579560909269 66.1033048735851 -0.840798520067317 0.401204800416705 KNOP1 other 1.04482168430161e-17 1 1.22468296841981e-12 8.90220287377907 -0.840798520067317 0.0841139213928875 -72.4260389282858 34.99323521492 -2.06971543166736 0.0394265407906121 -109.195421096991 68.2592858825007 -1.59971525756885 0.110826905542846 AQP9 other 1 1 1 -2.06971543166736 -1.59971525756885 5.92445645420815e-13 378.91100780342 56.9210846268335 6.65677771756295 1.55697994296102e-10 -124.035869745686 109.015159479755 -1.13778551843261 0.256218694165846 AAGAB other 7.36528426387157e-09 1 2.07016053216098e-06 6.65677771756295 -1.13778551843261 0.225952016562037 14.853569274702 8.96991355036964 1.65593226638063 0.0988887049536486 19.7188379936017 17.3039678589935 1.13955586107687 0.255473911155753 IQCH other 1 1 1 1.65593226638063 1.13955586107687 0.0766666180748291 17.9112141259034 20.4705509729727 0.874974696555634 0.382356797776236 -64.4262914759496 40.6119547384641 -1.58638735541904 0.11380903009925 LACTB other 1 1 1 0.874974696555634 -1.58638735541904 0.518910839688112 -7.49100611283704 11.3253951860885 -0.661434412640947 0.508897810079434 -24.4152316017484 21.7429856016754 -1.12290152093313 0.262476815670034 CORO2B other 1 1 1 -0.661434412640947 -1.12290152093313 1.56708722730237e-07 327.162249471409 92.2077607598458 3.54809884521 0.000457978151730161 -468.68484489755 173.680091245605 -2.69855250268594 0.00740649226373393 CSK other 0.00148136755596893 1 1 3.54809884521 -2.69855250268594 6.030483796058e-05 214.788314937504 58.9326351856034 3.64464128001481 0.000320688120627957 -112.731346603672 116.965327891295 -0.963801398551562 0.336001578695323 HERC1 other 0.458377073338368 1 1 3.64464128001481 -0.963801398551562 4.87046990743232e-15 107.212510490178 15.9701814072757 6.71329321540041 1.09865227761301e-10 -72.1574188382662 31.6454316344318 -2.28018437769562 0.0233679678313262 TRIP4 other 6.44996329841262e-11 1 1.4660415992468e-06 6.71329321540041 -2.28018437769562 2.65412629540266e-13 74.365709805583 11.5777504466749 6.42315708462527 5.96515014211499e-10 -43.0714771930067 22.8453854614125 -1.88534692337573 0.0604527000079221 MTFMT other 3.33809464172792e-09 1 7.76841503007635e-06 6.42315708462527 -1.88534692337573 0.459255660085966 -32.8687729650133 28.2097257376854 -1.16515748046085 0.244979810698027 -48.7524640721266 55.6638408477049 -0.875837228076165 0.381894164652745 RASL12 other 1 1 1 -1.16515748046085 -0.875837228076165 0.033185235904485 72.8771133115773 30.668241618279 2.37630556778126 0.0181847024329666 -13.0623855816167 59.7288981903669 -0.218694567912244 0.827053195685899 AP3B2 other 1 1 1 2.37630556778126 -0.218694567912244 7.47287594735407e-07 168.210522211424 37.8421921781872 4.4450522691543 1.28074876537402e-05 -100.30553113233 73.6489559736037 -1.36194097806736 0.174343381282728 ACSBG1 other 0.00672185191464499 1 0.130393031802729 4.4450522691543 -1.36194097806736 0.723761951388328 2.82197893874267 6.81367711451812 0.41416387822807 0.679080500477652 -6.37003976701718 13.6566086668371 -0.466443750598623 0.641271253909717 IGDCC4 other 1 1 1 0.41416387822807 -0.466443750598623 4.26704771122564e-08 743.547400998504 151.703552228153 4.90131832826336 1.64431057315272e-06 -358.379927998918 305.488335751731 -1.17313784540098 0.241774426167624 RAB11A other 0.000418323508745827 1 0.0179558714588277 4.90131832826336 -1.17313784540098 0.252559510664058 -1127.51056599731 680.598407351157 -1.65664590721788 0.0987398965187341 -945.23905401515 1318.86739709887 -0.716705148746877 0.474168736164912 CTSH other 1 1 1 -1.65664590721788 -0.716705148746877 9.03363288288115e-47 178.986418710534 10.1937069008933 17.5585211984905 1.03555630449978e-46 10.118864884203 39.3495317136934 0.257153374983665 0.79725408418315 TTC23 other 1.43743166432405e-42 1 1.64798430298095e-42 17.5585211984905 0.257153374983665 5.50976836840446e-08 920.932072988977 175.409916476779 5.25017109343923 3.08126627552775e-07 -158.574862037948 328.54257340428 -0.482661532704371 0.62972716994252 CD276 other 0.000536210657613122 1 0.00353729368430586 5.25017109343923 -0.482661532704371 0.000122587036285813 189.815582586847 53.8426255727828 3.52537753438975 0.000496044543586918 -117.56804421703 106.085442764088 -1.10823918111439 0.268737518850145 FAH other 0.898195214866152 1 1 3.52537753438975 -1.10823918111439 0.213010555413952 -203.026704957589 186.904777065197 -1.08625744159963 0.278326829771464 -616.009318609093 366.420197991322 -1.68115546573577 0.0938805606229129 CEMIP other 1 1 1 -1.08625744159963 -1.68115546573577 9.20665760351475e-14 242.390908911165 41.3003432228785 5.86898049740399 1.27227609551761e-08 -138.174319025117 72.2226934485669 -1.91317039599911 0.056776059865611 RPAP1 essential 1.17532190966469e-09 1 0.000157266048166932 5.86898049740399 -1.91317039599911 0.305768256134975 29.9437604737868 51.9726347214364 0.576144746832246 0.564997285554414 -115.398833174501 101.220938800469 -1.14006878954146 0.255267967823305 HOMER2 other 1 1 1 0.576144746832246 -1.14006878954146 0.0172778979547258 106.61771995976 92.0297790718668 1.15851326641241 0.247678302188964 -267.200877307038 159.565641488137 -1.67455145615983 0.0951801271148126 EHD4 other 1 1 1 1.15851326641241 -1.67455145615983 9.01198336403985e-12 463.297545676135 99.1857351179233 4.67100984960502 4.70901685759768e-06 -474.114721755989 173.13035385819 -2.73848410281847 0.00657834488113685 TMEM87A other 1.07053350381429e-07 1 0.0496471647296523 4.67100984960502 -2.73848410281847 0.00253975870037658 265.751768723363 106.560255821913 2.49391076132077 0.0132286302275101 -166.913617578282 186.101926244821 -0.896893551540695 0.370568849268838 ZNF106 other 1 1 1 2.49391076132077 -0.896893551540695 6.82059618932693e-08 77.9714968669644 15.2704413605531 5.10604081610777 6.2201523378685e-07 -15.1223740544726 28.9704976261819 -0.521992209095015 0.602103719584672 CEP152 other 0.000659960887279274 1 0.00699207324299798 5.10604081610777 -0.521992209095015 0.703282031980318 -4.88184195468334 6.27100952998457 -0.778477840185223 0.436966541546035 -7.38087028876985 11.9893466386302 -0.615619058422114 0.538662634058684 ATP8B4 other 1 1 1 -0.778477840185223 -0.615619058422114 0.922631441880898 -18.7439857426208 49.2873812025629 -0.380299891884824 0.704018533927039 -8.56677585804383 91.6347164860602 -0.0934883217469991 0.925584200280104 OCA2 other 1 1 1 -0.380299891884824 -0.0934883217469991 3.92903788868668e-08 48.2272356413225 14.0428339107593 3.43429509654543 0.000687132492822935 -81.1956071446749 26.8480541673197 -3.02426412873931 0.00273147143528104 DTWD1 other 0.000385910101426806 1 1 3.43429509654543 -3.02426412873931 0.245018426493478 -27.3627614003018 17.9986256815526 -1.52026948526114 0.129604826052093 -43.684804369611 31.9059077344975 -1.36917603890573 0.172073742860617 TGM5 other 1 1 1 -1.52026948526114 -1.36917603890573 0.10809309199174 10.2676975554944 9.79500858643812 1.04825814749266 0.295453661869134 38.2723200531121 18.0827724225507 2.11650731197521 0.0352132647391882 FAM189A1 other 1 1 1 1.04825814749266 2.11650731197521 9.41825054283383e-06 302.139000201269 132.470356637337 2.28080461071327 0.02333641757247 -609.847371729507 244.556325874357 -2.49368880379247 0.0132389271738043 TJP1 other 0.0773615099588371 1 1 2.28080461071327 -2.49368880379247 0.425564699396319 48.8375946406629 82.9483053966414 0.588771457200141 0.556501423935628 -102.261733910637 143.883283867839 -0.710726994558779 0.47786016631095 BMF other 1 1 1 0.588771457200141 -0.710726994558779 0.00436956491879692 95.4767068768348 40.645617134314 2.34900374525821 0.0195474669849959 -88.6856552414031 79.321995895226 -1.11804618933877 0.264544752228537 DMXL2 other 1 1 1 2.34900374525821 -1.11804618933877 0.998335567082072 -3.09114767854895 67.5365839803873 -0.0457699737885266 0.963527550512063 -6.76475483495579 131.873211083913 -0.0512974149893968 0.959126598561014 SCG3 other 1 1 1 -0.0457699737885266 -0.0512974149893968 6.85476466019861e-05 14.1689607295679 34.7574260336073 0.407652762200162 0.683851661737295 -218.387084477151 60.6413036524141 -3.60129270519825 0.000376751580576613 DNAJC17 essential 0.518083113017811 1 1 0.407652762200162 -3.60129270519825 9.23179259953573e-19 491.09066877001 62.9537055061496 7.80082228395655 1.32278180944221e-13 -177.133226156998 112.848594668133 -1.56965380630493 0.117658216404041 EIF3J other 1.3243929663294e-14 1 1.89448810748313e-09 7.80082228395655 -1.56965380630493 2.10862007446187e-08 225.652128862671 59.3442893128222 3.80242364472828 0.000177063068589405 -261.081602836446 106.449187548125 -2.45264063399651 0.0148118742587948 SPG11 other 0.000210630059237996 1 1 3.80242364472828 -2.45264063399651 0.0446358800489817 -88.7138498221792 148.752742150907 -0.596384634927809 0.551417980781873 -621.123702164712 258.673951848596 -2.40118379808208 0.0170186593525276 RHOV other 1 1 1 -0.596384634927809 -2.40118379808208 1.42630967564456e-07 96.941572851389 34.5201064704062 2.80826401663901 0.005343133064321 -175.414624849181 59.8014714201116 -2.93328275514953 0.00364079361244838 VPS18 essential 0.0013522842034786 1 1 2.80826401663901 -2.93328275514953 5.06724447968476e-10 71.0383573561102 13.5002413587134 5.26200646851845 2.89239267278547e-07 -24.097817848693 23.6081280940034 -1.0207424219633 0.308283498087318 OIP5 essential 5.56586133648574e-06 1 0.00332625157370329 5.26200646851845 -1.0207424219633 0.000358596765125149 39.0115361084006 13.341409051549 2.92409414610304 0.00374656841664976 -25.2124118889858 23.9332673340089 -1.05344629870737 0.293074835844528 SLC30A4 other 1 1 1 2.92409414610304 -1.05344629870737 1.5475923697479e-13 255.661336969344 47.5869534692824 5.37250902465052 1.67349549922592e-07 -243.099578545601 85.528541474195 -2.84232110539319 0.00481918210098615 BLOC1S6 other 1.96079953247059e-09 1 0.00195296924759665 5.37250902465052 -2.84232110539319 0.0170509137621912 111.36121958546 41.233890340177 2.70072066125067 0.00735637080818141 24.0413287273449 78.0769015781397 0.307918580801829 0.758381690078462 MYEF2 other 1 1 1 2.70072066125067 0.307918580801829 2.00196806151864e-06 63.3308768746827 17.7734630749296 3.56322662655507 0.000433498947884403 -131.188870839575 57.0474626545231 -2.29964427399775 0.0222373478836232 SGK3 other 0.0174051103268431 1 1 3.56322662655507 -2.29964427399775 0.000104932296738995 -21.7759280085114 28.2421246106934 -0.771044257777488 0.441352426525885 -184.838342011575 47.6864857712732 -3.87611582237674 0.00013321482981439 PDGFRL other 0.775659537494647 1 1 -0.771044257777488 -3.87611582237674 2.22502344067223e-12 98.1903357579622 15.7305714967946 6.24200689580605 1.68208330173748e-09 -98.304698213118 50.4903960592525 -1.94699796170649 0.0525795164097027 CSPP1 other 2.70674101557777e-08 1 2.15575795950675e-05 6.24200689580605 -1.94699796170649 0.00538561499181351 119.970742926969 104.337115775165 1.14983763961323 0.251224445567118 -304.959295584635 175.490156403139 -1.73775727274456 0.0833895720964455 ZDHHC2 other 1 1 1 1.14983763961323 -1.73775727274456 2.46683309828879e-17 100.018381362337 18.8481582053122 5.3065334168379 2.80692019860032e-07 -154.804801805058 38.8811080618942 -3.98149151404396 9.40878615684152e-05 BRF2 essential 3.45282628767481e-13 1 0.00323048445656911 5.3065334168379 -3.98149151404396 7.92995031367259e-20 153.657364170448 29.8676020704726 5.14461669229063 5.13820117622811e-07 -188.907015286768 50.70441817996 -3.72565196619158 0.000236896283116642 TRIM35 other 1.15666255275228e-15 1 0.00580411204866728 5.14461669229063 -3.72565196619158 4.85379014442495e-11 177.424332898658 27.0266796250584 6.5647847001581 2.67264230787698e-10 -33.7038784227458 86.7998171742829 -0.388294348075328 0.698105340349791 ZFAND1 other 5.60175920568084e-07 1 3.52147350485871e-06 6.5647847001581 -0.388294348075328 0.105239225983076 17.2315077142257 9.6260870477273 1.79008434359566 0.0746220793497396 -14.7459265187252 30.2783511490529 -0.487012203740374 0.626666407756729 RP1 other 1 1 1 1.79008434359566 -0.487012203740374 0.00631877120062947 291.050946133534 102.491035451071 2.83976978915859 0.00485933900745123 -169.392037796634 340.818019302534 -0.497016085426721 0.619583667669994 CA2 other 1 1 1 2.83976978915859 -0.497016085426721 6.00457305742674e-12 153.605606116201 30.496886903548 5.03676347694134 8.67242108594904e-07 -68.5615248381587 51.885478613965 -1.3214010291447 0.187486318524839 FZD3 other 7.17486434631921e-08 1 0.00966020984763864 5.03676347694134 -1.3214010291447 5.15285340122541e-27 129.231277797614 20.3825979994518 6.34027506214319 9.59558083388654e-10 -154.211065239963 34.6776658201977 -4.4469851586765 1.27345421114758e-05 INTS9 essential 7.97558649441668e-23 0.195538894121711 1.24042073439651e-05 6.34027506214319 -4.4469851586765 0.000386483871300057 63.7737565338122 20.6364219396984 3.09034951505476 0.00220895284821013 -117.640609686377 71.868785085589 -1.6368804557678 0.102824771381353 RIPK2 other 1 1 1 3.09034951505476 -1.6368804557678 0.00470903656173688 44.8070176733203 15.4508879021644 2.89996393456739 0.00403785303902963 -28.327550455669 49.582811127389 -0.571317959017882 0.568257630727179 EYA1 other 1 1 1 2.89996393456739 -0.571317959017882 1.11664432418105e-08 224.767980657661 42.45422912315 5.29436019214153 2.48324485463305e-07 -262.940481756018 147.851884291847 -1.77840467177946 0.07646682927032 NBN ts 0.000113417564007069 1 0.00286889278055756 5.29436019214153 -1.77840467177946 0.367703097136181 204.555972044088 157.106248555527 1.30202314627728 0.194014047216451 -58.0611632426101 515.892121724128 -0.112545163606236 0.910474482048009 TRPA1 other 1 1 1 1.30202314627728 -0.112545163606236 0.0378242674769986 67.4717647433658 30.1289632056786 2.23943201373252 0.0259391433586481 -67.6422328870554 109.929968561107 -0.615321133740296 0.538859035152555 CPQ other 1 1 1 2.23943201373252 -0.615321133740296 0.00024511202629889 108.170198422309 32.812502478224 3.29661532198272 0.00111017441755739 -173.05654599297 114.273428582663 -1.51440757610405 0.131096577979759 DECR1 other 1 1 1 3.29661532198272 -1.51440757610405 0.817702748230422 28.030601547274 140.610629217868 0.199349094042117 0.842140279580607 310.500029219096 489.693180413623 0.634070560175719 0.526573587927849 CALB1 other 1 1 1 0.199349094042117 0.634070560175719 2.30889508046226e-17 576.366770211068 76.8001620064612 7.50475982280582 9.70932002697574e-13 -652.622658303468 235.172506082075 -2.77508059584016 0.00591783077300223 IMPAD1 other 3.23453111821957e-13 1 1.36833447140169e-08 7.50475982280582 -2.77508059584016 0.598228811648123 -18.9180102843998 272.200068296641 -0.0695003877213696 0.944667209808207 -647.710170089944 691.18489044288 -0.937101170824091 0.349941586448873 SFRP1 other 1 1 1 -0.0695003877213696 -0.937101170824091 5.32224037985728e-12 1976.28544195228 270.972954096691 7.29329407999545 3.33714536554522e-12 56.0915976431593 987.77812028725 0.0567856247178746 0.954757810451494 LAPTM4B other 6.37125395872715e-08 1 4.64664120698516e-08 7.29329407999545 0.0567856247178746 5.01215921590149e-08 182.248089335064 33.7343934426891 5.40244156589571 1.45174282716869e-07 -78.6567188799615 111.869052311439 -0.703114196953992 0.482594921823376 UBE2W other 0.000489036374695508 1 0.00170028119917997 5.40244156589571 -0.703114196953992 1.70278156402547e-06 65.1010231875971 13.0486889599581 4.98908536998386 1.087937988764e-06 -15.4642666655944 48.0368762949831 -0.321924901415986 0.747758687834288 POP1 essential 0.0148908247774027 1 0.012031506217741 4.98908536998386 -0.321924901415986 0.0207969903959019 75.7010613528708 48.9738235979119 1.54574537561936 0.123337335047733 -330.270608242603 180.290105242325 -1.83188427228821 0.0680702062006832 NIPAL2 other 1 1 1 1.54574537561936 -1.83188427228821 8.62784740668887e-11 123.870402770787 45.6190767125171 2.71532024971473 0.0072849014290036 -566.709491801543 117.059112847981 -4.84122489923106 2.82291954399946e-06 IKBKB other 9.84005996732866e-07 0.0438907530701036 1 2.71532024971473 -4.84122489923106 0.175122985523465 238.873974868482 520.459325860251 0.458967613797014 0.646823735356046 -1898.2347292734 1334.76304566235 -1.4221510967375 0.156752176865754 PLAT other 1 1 1 0.458967613797014 -1.4221510967375 0.00113657006700239 74.1271436672667 24.556898467837 3.01858737431168 0.0027842222019589 -89.9328198148301 81.4349000811964 -1.1043523074893 0.270430868434811 JPH1 other 1 1 1 3.01858737431168 -1.1043523074893 0.645244405297037 -367.510734307934 569.509080228017 -0.645311456949541 0.519575372287502 -1316.64419123558 1469.08298214149 -0.896235411641828 0.371365296596742 DKK4 other 1 1 1 -0.645311456949541 -0.896235411641828 1.83805433684831e-17 162.891312764625 19.3292129504866 8.42720876333062 2.16548725042719e-15 -133.817861266878 72.095440877252 -1.8561209923761 0.064529762382868 STK3 other 2.5786064291645e-13 1 3.18434900175318e-11 8.42720876333062 -1.8561209923761 0.000247764715929324 88.3835105647883 22.4365593492316 3.93926311022439 0.000104303110945478 4.6490087709683 74.40349078136 0.0624837453477787 0.950224180964313 GDAP1 other 1 1 0.976381421560616 3.93926311022439 0.0624837453477787 5.47581910794452e-15 578.751346318114 81.1934500649628 7.12805461345781 9.7305788641798e-12 -507.635138171716 246.544490246096 -2.05900013285637 0.0404751674448011 RAB2A other 7.23793769688107e-11 1 1.33941418065435e-07 7.12805461345781 -2.05900013285637 7.2883136448364e-11 1096.2042353172 154.958259977568 7.07419040118214 1.30145627006597e-11 244.670846619376 641.442842327041 0.381438267721179 0.703179178758469 EIF3E other 8.34366146060871e-07 1 1.7852075656495e-07 7.07419040118214 0.381438267721179 2.89884518736525e-21 217.670180331041 21.0894259266093 10.3212947136887 3.01655782918991e-21 -54.2911582416559 87.231173373619 -0.622382528423892 0.534219534642371 EMC2 other 4.30623452583108e-17 1 4.64519740116954e-17 10.3212947136887 -0.622382528423892 2.90824200535439e-08 552.469180404289 96.0137353088572 5.7540640266427 2.36710464162048e-08 -105.366434292495 345.824365543044 -0.304681927564702 0.760844002536056 ESRP1 other 0.000288381277250942 1 0.000288479042674288 5.7540640266427 -0.304681927564702 0.813120731161246 24.3022170946506 37.9078153593169 0.641087249800525 0.522009780079322 24.7481066558082 161.756116654912 0.152996419347809 0.878515375786002 WISP1 other 1 1 1 0.641087249800525 0.152996419347809 0.000584741159121239 9748.64764370307 2529.80956404646 3.85351047061028 0.00014543193167774 -798.777887240332 10804.9867305354 -0.0739267809541076 0.941123182978479 NDRG1 other 1 1 1 3.85351047061028 -0.0739267809541076 0.00278628585895421 194.631421180261 57.6282332956393 3.37736227626102 0.000840849474654006 90.6928418254986 180.275259499567 0.503079801838901 0.615322907777644 ZC2HC1A other 1 1 1 3.37736227626102 0.503079801838901 0.000735029395166567 31.9848812610349 8.97960759254547 3.56194643600991 0.00043578820255992 -1.58820722454631 28.0904167345507 -0.0565391122372652 0.95495462509625 IL7 other 1 1 1 3.56194643600991 -0.0565391122372652 0.792503257474435 -23.9569522982478 44.4026069755917 -0.539539318297617 0.589964428761354 -81.467785895556 138.818324843274 -0.586866222363172 0.557789438015122 STMN2 other 1 1 1 -0.539539318297617 -0.586866222363172 2.02442938126152e-11 252.349414512963 38.2123101978032 6.60387747316755 2.16751617316734e-10 -77.6613793651211 121.516333332301 -0.639102392538019 0.523306276942732 ARMC1 other 2.37303612071476e-07 1 2.86610663577917e-06 6.60387747316755 -0.639102392538019 0.0161399224565698 120.205723043504 48.0077639147851 2.50388089844952 0.0128721531605996 -200.649629330986 189.703553650696 -1.05770095219431 0.291133701862452 TRPS1 other 1 1 1 2.50388089844952 -1.05770095219431 1.78036529318189e-05 68.7315664214625 18.2470017300187 3.7667320603357 0.000203207992248248 -133.105913745853 71.4384069476635 -1.86322623128156 0.0635201587258255 SPAG1 other 0.142749689207324 1 1 3.7667320603357 -1.86322623128156 1.82678794837318e-14 215.525745662389 26.8007569361749 8.04177830408508 2.80020876308265e-14 -82.2281259969029 105.127873073503 -0.782172449540674 0.434798636348943 CHRAC1 other 2.3775645148077e-10 1 4.05302216368582e-10 8.04177830408508 -0.782172449540674 0.655520454027872 27.7746671240334 40.3958381733589 0.687562590107384 0.492311991715346 -71.4687957301244 161.575374384913 -0.442324803530195 0.658604406570467 NCALD other 1 1 1 0.687562590107384 -0.442324803530195 9.67591912728941e-08 54.6751165995695 10.3692383558744 5.27281895960997 2.75556120278364e-07 -15.7001350346994 33.314811693283 -0.471265909567331 0.637831410738383 SNX16 other 0.00092743684835069 1 0.00317440650560675 5.27281895960997 -0.471265909567331 1.26380156108606e-14 595.838342102974 77.1375279397021 7.72436397713883 2.14655101622768e-13 -532.045218611938 309.638730125248 -1.71827735631369 0.0868798156183098 UBR5 other 1.65305244190056e-10 1 3.06677743688449e-09 7.72436397713883 -1.71827735631369 2.60355280523417e-05 218.785484462609 50.5046622899098 4.3319858908614 2.08837299829269e-05 -115.447105677674 191.988755915267 -0.601322223936 0.548131781663489 GSDMD other 0.205316174220767 1 0.208795532369303 4.3319858908614 -0.601322223936 6.81694333020374e-06 393.652420479027 80.277346507509 4.9036551107504 1.62957870535234e-06 657.844416945589 304.174835260026 2.16271808410195 0.0314441031128525 TSTA3 other 0.0565738126973609 1 0.0178047769346797 4.9036551107504 2.16271808410195 4.66930465158386e-15 169.443542256198 20.1305359276921 8.41723950444394 2.316352561741e-15 20.3478524703796 76.2375064600729 0.266900813197979 0.789750024381445 PYCR3 other 6.18822945474408e-11 1 3.40452225123988e-11 8.41723950444394 0.266900813197979 1.64474018210834e-11 1565.91231997297 213.401709365452 7.33786212223509 2.57062462985938e-12 887.871776780146 808.185845363354 1.09859852393352 0.272925531153574 EEF1D other 1.93585919434152e-07 1 3.58884904574668e-08 7.33786212223509 1.09859852393352 0.0139196456184524 -5.52791489677886 19.3131330880437 -0.286225692723107 0.774924757934827 233.757909695477 82.2295928613804 2.84274677231513 0.00481422292703375 ANXA13 other 1 1 1 -0.286225692723107 2.84274677231513 3.4570834324304e-11 714.957307759288 98.903796013454 7.22881564284986 5.05074306349077e-12 209.322985546185 433.991432881949 0.482320547565103 0.629970477690388 SQLE other 4.01229103167873e-07 1 6.99780451446647e-08 7.22881564284986 0.482320547565103 3.54136142060313e-08 40.0326453943405 37.8529740025119 1.05758256647639 0.291184136846785 -261.059846678707 63.7007688216435 -4.09822128536081 5.49992549444922e-05 SH2D4A other 0.00034871785908679 0.828838772013497 1 1.05758256647639 -4.09822128536081 1.07259233298462e-26 345.608843006973 57.8639701540029 5.97278137132912 7.27408982758638e-09 -478.204218329583 96.1790789579527 -4.97201910759244 1.17472352362783e-06 INTS10 essential 1.65715515446123e-22 0.018370326462492 9.08242855872435e-05 5.97278137132912 -4.97201910759244 3.00324664751813e-30 105.857510331929 15.3381605439773 6.90157793227006 3.66117421275284e-11 -135.115137768531 27.1820025385292 -4.97075730814945 1.18649110725011e-06 ERI1 other 4.70698847065517e-26 0.0185496019707482 4.95576541438225e-07 6.90157793227006 -4.97075730814945 0.000516297952566163 219.516987264462 163.072670283466 1.34612983820575 0.179381455167972 -583.507666284568 272.44406082795 -2.14175219863962 0.0331017251205925 SLC39A14 other 1 1 1 1.34612983820575 -2.14175219863962 1.89696079761463e-24 97.6575559413963 16.4877636761865 5.92303224738989 9.55348567402397e-09 -120.024846583426 27.7902430220232 -4.31895635055471 2.20167989600794e-05 MTMR9 other 2.89552096147897e-20 0.335844251337051 0.00011873071995677 5.92303224738989 -4.31895635055471 5.59963565875832e-21 205.636971545285 50.0249642158523 4.11068702933966 5.23295224019985e-05 -437.312159393662 87.0340985887683 -5.02460721124877 9.17078051443097e-07 LEPROTL1 other 8.28746077496231e-17 0.0143669447539076 0.504418308574328 4.11068702933966 -5.02460721124877 2.10799750191201e-31 133.638976712086 22.2200048799896 6.01435406670122 5.82638930147971e-09 -223.778657564142 38.6586602445805 -5.78857767311047 1.9589908604629e-08 DCTN6 essential 3.31145327575358e-27 0.000310872259646857 7.30570954512541e-05 6.01435406670122 -5.78857767311047 1.76385199661829e-28 136.587205361339 24.4835159116898 5.57874146237815 5.82979457848983e-08 -228.79885714544 40.82292033473 -5.60466657626131 5.09882308990063e-08 R3HCC1 other 2.74561201793603e-24 0.00080760258920936 0.000697943006936802 5.57874146237815 -5.60466657626131 0.000199243477523764 1227.20074051276 453.542338050795 2.70581296949464 0.00724587668357928 -642.253829246841 789.078996513997 -0.813928430593384 0.416400539587393 GSR other 1 1 1 2.70581296949464 -0.813928430593384 6.3162577972029e-10 73.9829662024151 31.4066836371867 2.3556440105894 0.0191980952937265 -185.687834970717 52.3663573778957 -3.5459375879579 0.000460223410746047 TNFRSF10A other 6.90240652078333e-06 1 1 2.3556440105894 -3.5459375879579 9.04803299243367e-12 63.7645188065993 12.5919371963603 5.06391652152063 7.59998943770418e-07 -24.9428884971818 21.9076199363741 -1.13854853104185 0.255896989902241 UBXN8 other 1.0744539178515e-07 1 0.00849526819346573 5.06391652152063 -1.13854853104185 5.72689827226144e-24 238.953051117764 85.2372189964018 2.803388636223 0.00542223120883378 -1027.30844128592 148.296848140762 -6.92737879574359 3.1161498664259e-11 PPP2CB other 8.71290303141855e-20 4.96901257700274e-07 1 2.803388636223 -6.92737879574359 3.02496415244927e-19 121.772797288971 22.5805363323595 5.39282129957479 1.59617778035273e-07 -127.95573012939 37.4921373728906 -3.41286837975556 0.000748805714608597 ERICH1 other 4.37349317161115e-15 1 0.00186545297189824 5.39282129957479 -3.41286837975556 0.648127440092744 43.4074987941687 47.8175752872261 0.907772895916044 0.364798829825811 57.9025688308195 79.9627108943138 0.724119632554091 0.4696123633514 NEFM other 1 1 1 0.907772895916044 0.724119632554091 6.29612358270666e-14 333.68383553741 167.27104672472 1.9948690587592 0.0470660130179941 -1436.405125588 278.695756368593 -5.15402582480754 4.94252538472987e-07 TUSC3 other 8.07792655661264e-10 0.0077652016319491 1 1.9948690587592 -5.15402582480754 0.000158978136652481 83.4122851584283 57.8340073983177 1.44227054134337 0.150448363175338 -219.173541183906 95.9393035220165 -2.28450210849831 0.023160856888951 ARHGEF10 other 1 1 1 1.44227054134337 -2.28450210849831 1.95217556224732e-07 985.016035625431 188.164761503344 5.23485921463528 3.82182047195141e-07 -460.458403127678 647.27583966734 -0.711378943734909 0.477596243939038 MCM4 essential 0.00183484981095626 1 0.00435802188416619 5.23485921463528 -0.711378943734909 1.22625881633307e-26 96.392538765504 28.822307084704 3.34437276246562 0.000940635272801064 -350.048787961907 48.9877268801484 -7.1456425977536 8.23389922520958e-12 KCTD9 other 1.89395674182642e-22 1.31371862138219e-07 1 3.34437276246562 -7.1456425977536 0.219345996109115 50.6297652577046 57.9460566378312 0.873739615693711 0.383033662573211 -65.9127667340366 98.226279028217 -0.671029864778876 0.502773025576954 FGL1 other 1 1 1 0.873739615693711 -0.671029864778876 0.00424248926085621 -41.110692592804 372.534749613824 -0.110353980763996 0.912210026632787 -1711.38260597243 629.352594525246 -2.71927472907841 0.00696349750572166 ASAH1 other 1 1 1 -0.110353980763996 -2.71927472907841 3.52654440356489e-18 706.246481317983 165.904968237351 4.25693388704065 2.8560140257836e-05 -1172.26852772516 281.979761307318 -4.15727895608633 4.3197048573542e-05 BNIP3L other 5.01121959746571e-14 0.653571344917691 0.282574027711029 4.25693388704065 -4.15727895608633 4.84534268165744e-07 230.71841995693 115.234406664815 2.00216607725525 0.0462781953505739 -934.360224031949 257.060380581889 -3.63478892358637 0.000333679449381438 MAN2B1 other 0.00443058134810756 1 1 2.00216607725525 -3.63478892358637 0.023582698744991 51.4826969674452 52.5392247461686 0.979890685790896 0.328010824596218 -297.367712510097 145.081952133131 -2.04965337271741 0.0413571773473212 KCNN4 other 1 1 1 0.979890685790896 -2.04965337271741 3.63944901740536e-10 1262.67738357388 286.558506865067 4.40635107080746 1.5119173190446e-05 -1800.7372440872 596.891957771761 -3.01685626794081 0.00279503347491324 NUCB1 other 4.02850611736599e-06 1 0.152975794340932 4.40635107080746 -3.01685626794081 0.00497466993817762 5.00790355255515 2.68098898706368 1.8679314151305 0.0628428941320754 -9.56761648591004 5.58441200283923 -1.7132719579153 0.0877977654241361 DHDH other 1 1 1 1.8679314151305 -1.7132719579153 2.00557361832518e-13 493.165914501793 97.9271528705605 5.03604873669366 8.64764592365589e-07 -758.648519889312 203.979043007252 -3.71924737318403 0.000242516062398971 GYS1 other 2.53283892258287e-09 1 0.00963434232354503 5.03604873669366 -3.71924737318403 0.00564168060975573 22.6654113698857 9.60189959389472 2.36051326596846 0.018968921200972 -77.0270869708048 45.2067447848795 -1.70388483703804 0.089566055687369 MAP4K1 other 1 1 1 2.36051326596846 -1.70388483703804 1.97386119901894e-24 931.736009480871 86.383455017602 10.7860470421218 9.43034634712508e-23 -657.590446509722 354.114465923729 -1.85699967041549 0.0644123838982739 ECH1 other 3.0125069619427e-20 1 1.46113786302356e-18 10.7860470421218 -1.85699967041549 1.97974341828089e-11 616.105512091673 88.8170927078582 6.93678990504902 3.02483447398221e-11 -322.814797224648 364.090754910565 -0.886632777324829 0.37607453828154 HNRNPL essential 2.32184308095983e-07 1 4.10379293085167e-07 6.93678990504902 -0.886632777324829 1.20950024193281e-25 156.148452187238 14.4094038715592 10.8365657302061 6.42941822478631e-23 -212.016785253683 72.7639886558575 -2.91375980303158 0.00387343692409312 NFKBIB other 1.86009042206846e-21 1 9.97524237575597e-19 10.8365657302061 -2.91375980303158 0.176144510750847 49.7922931406403 27.3619546568808 1.81976374732859 0.0698941389870947 66.6721186014769 50.7693758404147 1.31323494720616 0.190210537756473 TUBB4A other 1 1 1 1.81976374732859 1.31323494720616 5.20374892599307e-24 155.821583855765 15.5011160988884 10.0522815816429 2.26855365468477e-20 -275.806644535591 78.276870162471 -3.52347563160265 0.000500909016471781 SARS2 other 7.92218736493185e-20 1 3.47769275263175e-16 10.0522815816429 -3.52347563160265 3.9706931634459e-06 60.9346102370535 173.826774046257 0.350547897879288 0.726198874500003 -1647.10287287539 365.386042866343 -4.50784288298031 9.74065391656112e-06 SNRNP70 essential 0.0336476538670406 0.149889182468043 1 0.350547897879288 -4.50784288298031 1.58670485920401e-40 1289.1884346143 91.3957906432651 14.105555907342 2.9635022645467e-34 -675.181646233214 258.885271329227 -2.60803421827184 0.00961145213763323 CLPTM1 other 2.51794194107084e-36 1 4.69507663772134e-30 14.105555907342 -2.60803421827184 4.71081628395545e-06 447.795358147625 99.8890563829241 4.48292710295514 1.08770143410069e-05 -191.917263376182 282.943068630474 -0.678289326206565 0.498167026357819 RELB other 0.0396744947434728 1 0.111391503866252 4.48292710295514 -0.678289326206565 2.66680017632187e-11 178.433146086333 33.8394450967937 5.272933571338 2.74716147752374e-07 -281.309167710691 95.8527068244087 -2.93480671574584 0.00362351687580251 CLASRP essential 3.10922232557367e-07 1 0.00316500473825511 5.272933571338 -2.93480671574584 0.00260139301366441 6.99560702320219 6.70547325576051 1.04326820141926 0.297750427681479 -36.8672236664673 14.0949882543205 -2.61562641992031 0.00940374771194575 LIN7B other 1 1 1 1.04326820141926 -2.61562641992031 7.71255802136062e-15 269.684767850719 43.2939978352139 6.22914910462175 1.77462077703746e-09 -400.166489503674 121.691004296992 -3.28838184724855 0.00114031741292341 PPP1R37 other 1.01481838445063e-10 1 2.27133713253025e-05 6.22914910462175 -3.28838184724855 0.0017417799703469 239.440447824967 143.488363344046 1.66870986778805 0.0963212909145448 -670.185218260458 297.988828115622 -2.24902800047397 0.0253080613902221 FCGRT other 1 1 1 1.66870986778805 -2.24902800047397 9.58835141632339e-15 175.066688997337 39.9797092353487 4.37888849983304 1.70337921377599e-05 -409.855298225775 83.0103970350488 -4.9373971558373 1.38307112728985e-06 PIH1D1 other 1.25827935636412e-10 0.0215925064392491 0.171564354411518 4.37888849983304 -4.9373971558373 0.175470812774688 6.88203977562467 4.2391468212916 1.62344926131335 0.105651727831136 -3.38525242223355 11.9141556666019 -0.284136997783502 0.77652157371637 CKM other 1 1 1 1.62344926131335 -0.284136997783502 6.4111879893385e-19 343.124283784525 46.5151816777961 7.37660848368383 1.96990236377843e-12 -239.342467464094 103.287642859328 -2.31724203242846 0.0212332304296808 ARHGEF18 other 9.23211070464743e-15 1 2.75628738739878e-08 7.37660848368383 -2.31724203242846 0.00114271535580023 193.800673125956 118.744451530239 1.632081925753 0.10381937394229 -847.077019013624 333.732220118169 -2.5381937012665 0.0117008445957906 PPP1R13L other 1 1 1 1.632081925753 -2.5381937012665 7.62259785317727e-09 22.6188083858896 4.13566562604599 5.46920627321482 1.02443840782476e-07 -1.92698250514842 9.18330615426882 -0.209835376581959 0.83395324628265 PEX11G other 7.82307217671584e-05 1 0.00121047642268573 5.46920627321482 -0.209835376581959 7.95436201850882e-19 205.844949855516 27.8493264014615 7.39137984481782 1.79593521501173e-12 -269.901888735097 78.27075209816 -3.44831091435803 0.000653526760603071 ERCC2 ts 1.14256456033861e-14 1 2.51574604918843e-08 7.39137984481782 -3.44831091435803 3.78572889842502e-09 145.513476135493 64.6516939261131 2.25072952151559 0.0252044988333651 -420.398718597879 109.605470705371 -3.83556327884353 0.000155879315684083 DOT1L other 3.95343668862525e-05 1 1 2.25072952151559 -3.83556327884353 0.311426487821039 20.7681185797307 14.0451045957698 1.47867311618212 0.1403848010794 6.83463428848576 29.1620357224308 0.234367530221105 0.814875981283791 SLC17A7 other 1 1 1 1.47867311618212 0.234367530221105 7.38207364154988e-25 478.097057260958 47.965561346426 9.96750676611402 3.9493697402378e-20 -90.1073073078888 107.141842451801 -0.841009499611927 0.40108680585526 RNASEH2A other 1.12938344642072e-20 1 6.04964456809626e-16 9.96750676611402 -0.841009499611927 0.000487018270870998 85.9021451640319 36.1720849949012 2.3748187359435 0.0182513940794871 -213.717166654525 101.661930945694 -2.10223398932575 0.0364520933298283 KLC3 other 1 1 1 2.3748187359435 -2.10223398932575 0.0541206655594143 -15.3726754810279 57.682646923245 -0.266504335376347 0.790052741562201 -276.673818737427 119.719947183752 -2.31100852653047 0.021580350834582 CD37 other 1 1 1 -0.266504335376347 -2.31100852653047 2.5910443216654e-14 277.192327808672 79.9262274555707 3.46810223168305 0.000609462910560385 -587.870200049013 134.133264375189 -4.38273237281887 1.67765984580183e-05 SF3A2 essential 3.36239821622519e-10 0.256883275589176 1 3.46810223168305 -4.38273237281887 0.629441787277126 -6.00811915587911 6.89802898632092 -0.870990708765281 0.384532987006721 -11.7313770495298 15.2969029181712 -0.766911911011354 0.443803946612393 LYL1 other 1 1 1 -0.870990708765281 -0.766911911011354 1.91294856843209e-12 1152.85170624719 542.487668634976 2.12512057490271 0.0344813545207751 -4517.40529497485 910.410064302662 -4.96194569030276 1.234429888587e-06 OAZ1 other 2.33284077920293e-08 0.0192933640025776 1 2.12512057490271 -4.96194569030276 4.55805499650082e-20 338.775643888785 40.6165019180514 8.34083753870051 3.82687382096783e-15 -131.668567434047 90.0701762703845 -1.46184422953483 0.144946789940477 TRMT1 other 6.66980187637965e-16 1 5.60943164677464e-11 8.34083753870051 -1.46184422953483 1.66070906598707e-14 156.979296636944 29.9187871520571 5.24684693397242 3.13211312005282e-07 -229.398738721108 66.3471816952369 -3.45755061269733 0.0006331154848125 STX10 other 2.16473426751414e-10 1 0.00359441301657261 5.24684693397242 -3.45755061269733 0.307135605103343 -1.25175719443398 6.58638797337685 -0.190052149902765 0.849410022564704 18.4160001344712 14.6854391945564 1.25403128163151 0.210907296763658 RETN other 1 1 1 -0.190052149902765 1.25403128163151 0.734892597053125 -7.67092934685009 11.3959520405281 -0.673127556133048 0.501437649103446 0.912445050351515 25.4091561917894 0.0359100886099617 0.971380390952419 FCER2 other 1 1 1 -0.673127556133048 0.0359100886099617 5.69540905913115e-08 146.897743857749 32.1296320849665 4.57203317701488 7.32965980412386e-06 -162.981370893216 85.876717192013 -1.89785283162144 0.0587703013318577 DMPK other 0.000553593760547547 1 0.0761038577462181 4.57203317701488 -1.89785283162144 0.0142546767548688 -46.1681503246346 48.026193188996 -0.961311885431987 0.337246034449157 -293.254173427827 100.021925122021 -2.93189891186431 0.00365439646517885 IL4I1 other 1 1 1 -0.961311885431987 -2.93189891186431 0.0333241207069825 -2.10997657699677 5.67186401653245 -0.372007609993219 0.710177905302952 18.1800681396457 9.5532247804783 1.9030294541793 0.0580963405902723 TLE6 other 1 1 1 -0.372007609993219 1.9030294541793 1.12525780419201e-11 102.300057110484 22.0494400812607 4.63957618576567 5.45767831542123e-06 -147.71347853195 48.2045472511913 -3.06430589965348 0.00240340783857304 CCDC130 essential 1.33253029172418e-07 1 0.0572619608853996 4.63957618576567 -3.06430589965348 2.16964513737202e-09 328.007569370845 98.3469782415439 3.33520739768177 0.000970919768982377 -804.016321016796 205.644626237761 -3.90973659621532 0.00011673145083274 PTOV1 other 2.3030783133204e-05 1 1 3.33520739768177 -3.90973659621532 1.11235631625067e-05 125.981950338672 350.488309604336 0.359446939844847 0.719540687683748 -2221.49665902215 589.281696747031 -3.7698382136851 0.000200525762677683 AES other 0.0907187646349758 1 1 0.359446939844847 -3.7698382136851 0.524347971392048 7.98951636949134 10.2729451359488 0.777724037630953 0.437410139175646 27.0915761226072 25.3531359007887 1.06856904126658 0.286214806878062 NOVA2 other 1 1 1 0.777724037630953 1.06856904126658 3.18978621535042e-17 300.98850784895 70.3610569549148 4.27777126829994 2.61978334583795e-05 -513.942692473422 118.29918970511 -4.34443121507891 1.97588994038103e-05 SGTA other 4.45645032146608e-13 0.301757911694992 0.259934903574041 4.27777126829994 -4.34443121507891 0.25512897550098 -15.8194953784313 17.9946749129347 -0.87912093188525 0.380108842434202 -67.7622910349592 41.3044343285919 -1.64055729454821 0.102040965207459 LILRB1 other 1 1 1 -0.87912093188525 -1.64055729454821 0.964114953209417 -0.315264610542547 3.98347580711635 -0.0791430965839776 0.936976785313599 1.8662443458913 9.14355028199495 0.204105001704449 0.838423516197166 LILRA1 other 1 1 1 -0.0791430965839776 0.204105001704449 2.58810861878421e-27 166.659681112955 14.9743360239393 11.1296875431751 5.67033535349718e-24 13.9646925548573 34.5126519479623 0.404625311781691 0.686069789656813 SNAPC2 essential 4.01130954825365e-23 1 8.83268138014256e-20 11.1296875431751 0.404625311781691 3.05818631965136e-17 649.010137492346 80.1317498490914 8.09928821864739 1.93795700792922e-14 -88.1431972920585 175.184254461137 -0.503145659769395 0.615273587751668 C19orf53 essential 4.27381538171278e-13 1 2.81158802710371e-10 8.09928821864739 -0.503145659769395 1.13130945939443e-39 447.672464750561 34.9014549319728 12.8267565241372 8.56012534655616e-30 -179.166175316453 80.4404124910101 -2.22731547201447 0.0267416259736019 TIMM44 essential 1.79436993354551e-35 1 1.34941815963111e-25 12.8267565241372 -2.22731547201447 2.09576928076835e-16 68.8773093207705 9.35370463240734 7.36363954471414 2.15367371865229e-12 -46.8492337050511 23.0844944252064 -2.02946760895468 0.0433878066679651 CCDC61 other 2.87015603001225e-12 1 3.01105122604776e-08 7.36363954471414 -2.02946760895468 0.350910977788873 2.42974682411825 45.5960572240514 0.0532885291414317 0.957541572070769 -149.861919036155 115.570633562136 -1.29671279300881 0.195841227725125 IL27RA other 1 1 1 0.0532885291414317 -1.29671279300881 6.48010584192828e-15 261.560972255877 39.331993248105 6.65008179488791 1.62839688149265e-10 -217.16891017017 98.8780505128474 -2.19633082411908 0.028921807973463 ASF1B other 8.54661159491921e-11 1 2.16413945550374e-06 6.65008179488791 -2.19633082411908 0.0190778034032919 88.5665454656638 66.6623198268498 1.32858480916519 0.185102641371578 -253.715340823675 148.215585708863 -1.71179933345231 0.0880777059021623 TNNT1 other 1 1 1 1.32858480916519 -1.71179933345231 1.34804114689471e-18 154.07798724166 20.5400164128685 7.50135657852392 8.98970598912279e-13 -125.193260100352 42.4053932586553 -2.95229569825529 0.00342950855234702 VRK3 other 1.92931648943571e-14 1 1.2677283385861e-08 7.50135657852392 -2.95229569825529 4.55039346283229e-30 349.297839152177 40.9719169136146 8.52529892337324 1.06947831570751e-15 -475.765518190579 91.8215528519471 -5.18141442192447 4.29578854520708e-07 FAM32A essential 7.13001151691192e-26 0.00675426832962909 1.57812220265801e-11 8.52529892337324 -5.18141442192447 1.09938993524461e-16 525.124341284638 93.6091481031093 5.60975451572554 4.99690660244882e-08 -875.745253648813 207.333894433495 -4.22384027484575 3.28310094258826e-05 PPP6R1 other 1.51517920875412e-12 0.498276230056621 0.00060042829735025 5.60975451572554 -4.22384027484575 3.64271662980536e-19 186.566449547361 24.2925514366381 7.67998577810898 2.88213872724998e-13 -123.639568237018 54.6633252275853 -2.26183767127699 0.0244969646464206 C19orf44 other 5.26190417175384e-15 1 4.10906518344029e-09 7.67998577810898 -2.26183767127699 3.25926036748209e-18 60.0409306612124 9.96771484195033 6.02354016073201 5.54199476831544e-09 -91.3491273030066 22.4458906655089 -4.06974838576474 6.17912192824615e-05 MED26 other 4.63564602066978e-14 0.929278146788938 6.95686603266638e-05 6.02354016073201 -4.06974838576474 0.051435256157324 105.529995330067 71.4257859224842 1.47747755193894 0.140704593903981 -140.688471580808 141.978648383293 -0.9909128814989 0.322608794150476 OLFM2 other 1 1 1 1.47747755193894 -0.9909128814989 0.134157916530336 -29.3492227979275 18.3677040649581 -1.5978710618449 0.111228435954169 -74.8329184501016 41.4981775901229 -1.80328204262909 0.0724464363595039 RASAL3 other 1 1 1 -1.5978710618449 -1.80328204262909 2.45668691825037e-21 161.826574764628 21.4895074355856 7.53049250894654 7.41095627333622e-13 -165.976830533005 48.3607002457351 -3.43206011678135 0.000691863954747977 AKAP8 other 3.65063676052005e-17 1 1.04672346404601e-08 7.53049250894654 -3.43206011678135 0.00208348853161844 79.9069298943788 43.6337058828624 1.83131201619441 0.0681476979837608 -189.390026129749 98.5420125135337 -1.92192163828335 0.0556602235625998 EPHX3 other 1 1 1 1.83131201619441 -1.92192163828335 1.50838563768105e-21 546.243732590528 60.502949101055 9.02838193355112 3.22967990779819e-17 -159.033441322515 136.25706952297 -1.16715735836154 0.244165269727082 ILVBL other 2.24568453737955e-17 1 4.84322798973417e-13 9.02838193355112 -1.16715735836154 8.79075402528051e-11 41.3878337200527 11.0780539566066 3.73602023263032 0.000227802907601631 -97.5316617842444 24.5716386902279 -3.96927787413024 9.23125906033925e-05 ZNF419 other 1.00232177396248e-06 1 1 3.73602023263032 -3.96927787413024 0.124732923869885 32.4550835654596 16.6505490409955 1.94918999280754 0.052296741834451 53.590953130677 37.4982550765444 1.42915858408032 0.154101899084389 SYDE1 other 1 1 1 1.94918999280754 1.42915858408032 0.371397169247358 188.802750696378 176.656807993568 1.0687544558331 0.286124420218431 -139.061379738404 397.844060928028 -0.349537402705027 0.726955373219176 CASP14 other 1 1 1 1.0687544558331 -0.349537402705027 0.0837903305969805 67.2633814482111 44.0808872229431 1.52590806777596 0.12819467577352 234.267669672243 110.577519675949 2.11858314744961 0.0350323073498178 SLC1A6 other 1 1 1 1.52590806777596 2.11858314744961 0.0163729255194198 2.52966340869255 3.10439460386878 0.814865289850722 0.415862314607896 -15.1209441193072 6.91845987828434 -2.18559395954132 0.0296982147607212 AURKC other 1 1 1 0.814865289850722 -2.18559395954132 8.24648498998135e-23 205.791350362342 19.3781683005051 10.6197524539499 8.69166294174025e-22 -92.1805320976764 64.0002403676747 -1.44031540456893 0.151103471050993 POP4 essential 1.24291021768999e-18 1 1.34164509168703e-17 10.6197524539499 -1.44031540456893 7.26119142768698e-06 82.687460186882 19.2828636484568 4.28813176789223 2.61995154204762e-05 -102.168699886576 65.1425201082204 -1.56838727941204 0.118119325764427 CCNE1 og 0.0601226650212482 1 0.259934903574041 4.28813176789223 -1.56838727941204 4.97766901627164e-22 721.398006454807 69.8672161006689 10.3252719475093 6.42218548601469e-21 -379.70084115768 247.0998505812 -1.53662918154175 0.125701422443266 URI1 essential 7.4525660511619e-18 1 9.87089909200458e-17 10.3252719475093 -1.53662918154175 1.99036279327657e-20 479.889510809023 47.4384755424302 10.1160398879133 1.48850362244995e-20 -73.8043671916078 173.776657229688 -0.424708176392515 0.671394040956194 PDCD5 other 2.92523619727858e-16 1 2.28455535973618e-16 10.1160398879133 -0.424708176392515 3.99149862112525e-27 373.804779542971 30.6746245034244 12.1861240551206 1.93821228866031e-27 3.09935686772626 112.339004790852 0.0275893210332113 0.978010386096126 ANKRD27 other 6.18003731508823e-23 1 3.04396239934101e-23 12.1861240551206 0.0275893210332113 3.08362274490187e-50 6018.58590874944 323.255312290685 18.6186759502881 2.44392577498439e-50 -741.461047790069 2439.59159631432 -0.303928349691912 0.761416568952767 RPS16 essential 4.90943577215826e-46 1 3.89219618924014e-46 18.6186759502881 -0.303928349691912 2.217679527544e-65 693.512433515301 30.1150714549945 23.0287493938615 1.16863884995754e-65 48.0660769044439 227.27693080553 0.211486826815572 0.832666954774569 TIMM50 other 3.53675531052717e-61 1 1.86409582956727e-61 23.0287493938615 0.211486826815572 1.30996405211218e-48 1382.7808304818 77.5726970535182 17.8256123997829 1.13793746803485e-47 -691.299666575185 564.966074743495 -1.22361270433636 0.222153413933997 FBL essential 2.08533177455738e-44 1 1.81125506787107e-43 17.8256123997829 -1.22361270433636 1.51915220601594e-35 148.06324525966 10.2610143172654 14.429688984112 1.94836469114764e-35 -34.4921791051849 74.3793545998562 -0.463733240100628 0.643209761020617 DYRK1B other 2.40147580727e-31 1 3.08971672722193e-31 14.429688984112 -0.463733240100628 0.00167648534917613 8.82765136854112 2.60881538366827 3.38377771911499 0.0008209990871469 -4.89543153613877 11.5635130810427 -0.42335158025327 0.672375791397806 CNTD2 other 1 1 1 3.38377771911499 -0.42335158025327 9.22441769461835e-15 6151.79397035258 747.905844108761 8.22535887212292 8.49619527825453e-15 -810.345964274542 2720.46214543847 -0.29787070025337 0.766032636140442 GPI other 1.21107379912644e-10 1 1.23874527156951e-10 8.22535887212292 -0.29787070025337 7.11301278986708e-30 721.196895876138 61.9547083968689 11.6407116511033 1.189050045631e-25 -877.005864390199 274.612793785363 -3.19360890765951 0.00157157165734889 AKT2 og 1.11368441250949e-25 1 1.86062551140339e-21 11.6407116511033 -3.19360890765951 2.17700680450138e-16 2326.97973742285 295.318071275804 7.87957109217891 8.18076883860589e-14 -3289.95260847591 1309.93299822551 -2.51154266129079 0.0126067830635083 PLD3 other 2.98010461468193e-12 1 1.17524925135412e-09 7.87957109217891 -2.51154266129079 0.00560706231679434 101.693269341431 31.530684422736 3.22521604599557 0.00141430706035966 165.446156909836 139.202650233553 1.18852734938776 0.235673914765703 PRX other 1 1 1 3.22521604599557 1.18852734938776 4.67301983251193e-14 74.8542980951552 24.1033240779351 3.10555912757606 0.00209914779362592 -184.924872165102 41.4067611361352 -4.46605498935583 1.16751905061942e-05 PIAS4 other 6.02025145022512e-10 0.179447678080205 1 3.10555912757606 -4.46605498935583 9.31522583272088e-08 118.875621957202 24.0607987746478 4.94063489207427 1.36216413707419e-06 -169.532164649464 98.8098817411744 -1.71574099333042 0.087348156555223 NUMBL other 0.000893609614132914 1 0.0149674595381712 4.94063489207427 -1.71574099333042 0.180478514916819 13.9126247973111 8.45352702606694 1.64577752628113 0.100960330659903 24.7651232286082 14.9452827362201 1.65705284173645 0.0986575264047322 EBI3 other 1 1 1 1.64577752628113 1.65705284173645 6.35786769255342e-23 86.5676305476115 17.9074249941246 4.83417524161148 2.23466805652015e-06 -169.734935042806 31.9804750677779 -5.30745508573833 2.30361665647443e-07 CCDC94 essential 9.5927507745246e-19 0.00363119093560064 0.0241478230187567 4.83417524161148 -5.30745508573833 7.74201651270852e-15 366.547880472553 46.1815091481506 7.93711351650863 5.50496827366361e-14 -234.54132014588 186.958163200413 -1.25451232581088 0.210736747987434 TBCB essential 1.01853969241193e-10 1 7.92825530773032e-10 7.93711351650863 -1.25451232581088 0.0153620977243664 35.9030295665325 13.4391596249733 2.67152341131627 0.00800445913891383 60.3833263892105 24.0967583412985 2.50586927643798 0.0127973269048626 FSD1 other 1 1 1 2.67152341131627 2.50586927643798 4.52281739133419e-20 177.846374797314 19.1372869107142 9.29318641806773 5.12302559757573e-18 -158.07636224553 77.4741249357745 -2.0403762207908 0.0422821082428298 POLR2I essential 6.61869097047845e-16 1 7.7424285856162e-14 9.29318641806773 -2.0403762207908 0.95358832804315 4.27296668898937 27.7077557960887 0.154215546016634 0.877555852173541 33.8729577295714 114.472766216253 0.29590407263839 0.767532489945366 CLIP3 other 1 1 1 0.154215546016634 0.29590407263839 0.499751408361425 -6.97148429618672 7.3991105049728 -0.942205727499451 0.346923398339313 0.485330217230457 12.4327975322345 0.0390362841486111 0.968890095879358 ZFR2 other 1 1 1 -0.942205727499451 0.0390362841486111 1.92265295524099e-06 1982.97848111147 408.5021841727 4.85426653257046 2.0433495054715e-06 240.292140965377 941.168189831354 0.255312646094036 0.798675294325791 SLC1A5 other 0.0167424619342386 1 0.0221682987848603 4.85426653257046 0.255312646094036 7.14909197626882e-20 179.028334419706 41.7373289664027 4.28940564365818 2.49454793529111e-05 -665.400668976637 101.344361488791 -6.56573941758204 2.6289718055207e-10 PRKD2 other 1.04305251933762e-15 4.18926657209724e-06 0.247933119288584 4.28940564365818 -6.56573941758204 0.0909210965632696 -35.0746978237188 46.9096738946128 -0.747707133980884 0.455285143625428 99.5833251200978 79.0092069410239 1.26040152756414 0.208608716978603 TJP3 other 1 1 1 -0.747707133980884 1.26040152756414 0.15208197119406 -34.0338479616151 46.6968577844867 -0.72882522671411 0.466744983448346 295.547759711647 186.553022939755 1.58425607398005 0.114314728905998 APLP1 other 1 1 1 -0.72882522671411 1.58425607398005 7.12771927311359e-15 102.954721987625 30.8015522564638 3.34251732284109 0.000947141064847021 -235.338745431035 51.8785575402431 -4.53633941630852 8.60656320454443e-06 CACTIN other 9.38578073883598e-11 0.132566893039598 1 3.34251732284109 -4.53633941630852 3.66234432902256e-11 87.2726936510936 24.2641711611442 3.59677209130675 0.000382577419962278 -205.528372198285 49.8742131547498 -4.12093463130077 5.01362594445454e-05 CCDC9 other 4.24575578063586e-07 0.756856972574858 1 3.59677209130675 -4.12093463130077 7.05750482559936e-33 2483.32559365098 201.465840490613 12.326286121774 4.71903073212284e-28 -1518.27298633585 611.112672676945 -2.48444035644873 0.0135752887796507 HNRNPUL1 other 1.11162758508016e-28 1 7.41926011704352e-24 12.326286121774 -2.48444035644873 5.54397606377082e-16 185.559591983428 67.4353067294111 2.7516682429873 0.00632921669091108 -611.307737632993 113.580199182057 -5.3821682127281 1.59434798108636e-07 FZR1 other 7.51485955444135e-12 0.00251604054895238 1 2.7516682429873 -5.3821682127281 0.000104278424401334 328.140162694293 94.3553651111614 3.47770539923942 0.000588307885165702 -400.820568140956 286.211097693146 -1.40043685018352 0.162518060543442 TGFB1 other 0.771243226872265 1 1 3.47770539923942 -1.40043685018352 0.150757867211449 83.7437042256042 72.2182518590868 1.15959196006303 0.247235625948056 -355.213331342172 280.609991726563 -1.26586130863189 0.206649883411132 DENND3 other 1 1 1 1.15959196006303 -1.26586130863189 0.624813323470183 -0.42212828933367 1.29336181374013 -0.326380665370784 0.744388274491068 -3.70265947945464 3.81530714137908 -0.970474811659928 0.332675235662963 CEACAM4 other 1 1 1 -0.326380665370784 -0.970474811659928 0.00201666827666999 72.9405231810347 83.4040593071599 0.874544042423761 0.382590753504834 -358.556325589739 153.30195980788 -2.33888937909917 0.0200627962198484 PLIN3 other 1 1 1 0.874544042423761 -2.33888937909917 0.00183426845533505 587.350346959218 443.429612594259 1.32456274970668 0.186436253155476 -2464.47095897424 950.823963005706 -2.59193189787061 0.0100633941407736 MYH14 other 1 1 1 1.32456274970668 -2.59193189787061 3.76160652105757e-29 547.365645084502 60.8254099201868 8.99896352203361 3.9716220356558e-17 -526.422936999128 129.128692446389 -4.07673094976693 5.99538532713808e-05 MRPL4 essential 5.8733724219793e-25 0.90224553788101 5.95226994483734e-13 8.99896352203361 -4.07673094976693 0.332755546091101 -6.19155274799727 5.28960043478238 -1.17051426177372 0.242818577997949 -15.1345452552708 11.6629651611359 -1.29765844673043 0.195504144976272 SIGLEC8 other 1 1 1 -1.17051426177372 -1.29765844673043 0.00277520582807823 -112.620951469502 54.425707385515 -2.06926022424975 0.0394660630054032 -509.218584963275 154.557868821611 -3.29467913116095 0.00111603709382189 CD79A og 1 1 1 -2.06926022424975 -3.29467913116095 5.84612114072007e-05 166.251475839086 37.0636645431894 4.48556498360697 1.07231447959706e-05 143.465789891296 78.6839340008336 1.82331744991012 0.0693487996727927 ICAM4 other 0.444889818808797 1 0.109880064724311 4.48556498360697 1.82331744991012 7.05006416029063e-17 6967.28925878183 866.650863515427 8.0393265063167 2.81450101364598e-14 -4490.35275178724 2491.93688064097 -1.80195284506253 0.0726640509831473 RPS19 essential 9.76997891333076e-13 1 4.07314586694846e-10 8.0393265063167 -1.80195284506253 7.54081000926829e-08 228.76408651181 149.643562983858 1.52872654159195 0.127490061708233 -1392.76463963402 309.425280115307 -4.50113397042091 1.00173366419804e-05 NOP53 other 0.00072768816589439 0.154096689563584 1 1.52872654159195 -4.50113397042091 0.783796098743875 7.69470170583665 27.9682483645081 0.275122760837653 0.783431566353336 42.8763483077979 61.4019754474226 0.698289395338953 0.485594983434015 NKG7 other 1 1 1 0.275122760837653 0.698289395338953 0.00187882978856859 131.848167103071 39.2892423555902 3.3558337905773 0.000903573706204932 37.0604975005952 83.4087020415276 0.444324112394693 0.657160284522004 ICAM5 other 1 1 1 3.3558337905773 0.444324112394693 0.00463841536591279 526.982163958268 167.400903405508 3.14802461180104 0.00182742909012218 97.8744874410422 367.514834208393 0.266314386062425 0.790199606575325 ETFB other 1 1 1 3.14802461180104 0.266314386062425 0.678060222548516 -4.74149859109409 9.52027859992791 -0.498041999645892 0.618858360825112 -18.0537265308596 20.9009840454367 -0.863773997033464 0.388475903632889 CD33 other 1 1 1 -0.498041999645892 -0.863773997033464 0.104799277286865 1466.67884113648 815.602240263144 1.79827711196976 0.0732459257277249 -1216.70353792172 2350.78132917699 -0.517574103052659 0.605177675027166 CEACAM5 other 1 1 1 1.79827711196976 -0.517574103052659 1.59270928976995e-17 293.590224058227 45.3734658599172 6.47052673835047 4.52652298886208e-10 -331.786045834565 101.022773741372 -3.28426980914195 0.0011564361326999 BABAM1 other 2.23743801026882e-13 1 5.92023660701632e-06 6.47052673835047 -3.28426980914195 7.87120371069009e-08 536.763539704674 147.316862344875 3.6435987785844 0.000321929252931451 -755.528468238369 313.695409100123 -2.408477925787 0.0166845673913716 TYK2 other 0.000758547901599204 1 1 3.6435987785844 -2.408477925787 8.60501980298919e-18 476.565993846984 89.6586178988784 5.3153395068445 2.21503813599276e-07 -906.942787436261 185.391488981751 -4.89204112021311 1.70746029732495e-06 NAPA essential 1.21502879618207e-13 0.0266244284161879 0.00256501416147962 5.3153395068445 -4.89204112021311 3.16202467327288e-07 200.737636441247 55.6996862956302 3.60392759441798 0.000373125493562481 -404.627386285279 151.389227795914 -2.67276207281242 0.00798082634786343 RABAC1 other 0.00293246168199327 1 1 3.60392759441798 -2.67276207281242 0.00223985771370084 32.5993658149887 9.44084005173956 3.45301537112495 0.000643393582412057 50.7301289478251 25.6597762075676 1.97702928261953 0.049055523253131 ATP1A3 other 1 1 1 3.45301537112495 1.97702928261953 0.358634201747712 8.63653907766055 18.9566741721585 0.455593581407067 0.64904441575583 -40.2713242287351 39.1662170753862 -1.02821582567501 0.304758448453311 MEIS3 other 1 1 1 0.455593581407067 -1.02821582567501 3.15858238540396e-07 175.918055788147 145.848891749417 1.20616655826492 0.228801362338682 -1037.54321751063 267.906621074772 -3.87277930402869 0.000134846280560713 PTPRS other 0.00292958516246217 1 1 1.20616655826492 -3.87277930402869 0.215986887856703 34.4388126532538 40.4925744298963 0.850496989586989 0.39580521847991 -123.187977609696 110.666108436481 -1.11314999099658 0.26663772653312 CNFN other 1 1 1 0.850496989586989 -1.11314999099658 1.85372409712153e-15 448.386344598608 66.4153868964017 6.7512419267846 8.99768232119048e-11 -495.272200164869 181.513092501757 -2.72857562690733 0.00677998073117604 MEGF8 other 2.47991209712918e-11 1 1.20415982504492e-06 6.7512419267846 -2.72857562690733 1.42389856935191e-17 929.293578324694 144.843935826591 6.41582661380632 6.18871532323902e-10 -1097.39822812515 301.653931598239 -3.63793775970647 0.000328748186459781 KDELR1 other 2.00228616822265e-13 1 8.05399412166326e-06 6.41582661380632 -3.63793775970647 1.72385217905967e-10 245.912360100299 65.8925845345258 3.73201873681929 0.000231111229053307 -527.641347842422 137.198985185841 -3.8458108646191 0.000149596156963685 CYTH2 other 1.93864416057051e-06 1 1 3.73201873681929 -3.8458108646191 2.72743345627756e-21 290.732021632578 35.0913627875267 8.2850023064912 5.36705535436638e-15 -194.599562031406 73.0658752763626 -2.66334402065748 0.00819651516292835 GRWD1 essential 4.0524206293372e-17 1 7.85253868897345e-11 8.2850023064912 -2.66334402065748 0.65126994648584 -0.297141767437724 34.2639931922379 -0.00867212895387331 0.993087085933424 -60.2941429415416 71.3586537103502 -0.844945074023955 0.398884103615334 GRIN2D other 1 1 1 -0.00867212895387331 -0.844945074023955 0.332554940161337 5.33484334402447 15.6425648563641 0.341046586222337 0.733331800893432 -41.4592565917928 34.5590969895606 -1.19966261283727 0.231314324872952 CLEC11A other 1 1 1 0.341046586222337 -1.19966261283727 0.815062594322116 -1.02528062578991 9.74221991625126 -0.105240965057627 0.916262171976887 -12.5181400299633 20.2892784116983 -0.616983008264388 0.537762034386368 CCDC114 other 1 1 1 -0.105240965057627 -0.616983008264388 0.00512832341524244 21.3529864865874 29.4176839846953 0.725855458155589 0.468551468753679 -159.193025423961 61.2656648816969 -2.59840525245846 0.00987642346898261 CARD8 other 1 1 1 0.725855458155589 -2.59840525245846 1.24291212637486e-12 257.719159118005 56.3706257256737 4.5718697601866 7.33497138445077e-06 -448.129036011978 117.333670555498 -3.81927058013596 0.000165722428018399 LIG1 other 1.52617179997569e-08 1 0.0761516729133679 4.5718697601866 -3.81927058013596 0.310132808734813 -2.38800746459292 2.22087421598902 -1.07525561213717 0.283209677660762 -6.94188474216575 4.87351080988161 -1.42441147931595 0.155469465296131 SIGLEC6 other 1 1 1 -1.07525561213717 -1.42441147931595 1.63331920984745e-05 19.0717986443661 7.75914869835486 2.45797566019192 0.0145938630244065 -51.8217792203242 17.9467761792739 -2.8875257986541 0.00419360171399062 ZNF175 other 0.131335197663834 1 1 2.45797566019192 -2.8875257986541 0.101845955274278 -2.84335829127251 15.0965812354007 -0.188344516346852 0.850746517755738 -63.5017957088685 31.4230552949508 -2.02086637065723 0.0442696442295512 PLA2G4C other 1 1 1 -0.188344516346852 -2.02086637065723 0.409660083208072 -5.44844818322288 5.90284864541086 -0.923020140023198 0.356811758850504 -16.9952632696297 13.6531863968247 -1.24478365530718 0.214278792693552 SIGLEC5 other 1 1 1 -0.923020140023198 -1.24478365530718 0.65976184643287 1.58697401883968 5.7502262090736 0.275984624106702 0.782768676233986 -9.3424945503252 13.3001733523059 -0.702434043741651 0.483007010456822 HAS1 other 1 1 1 0.275984624106702 -0.702434043741651 1.93984629056243e-07 276.743620014493 92.5499104757341 2.99020948363913 0.00304314247664408 -511.39538388784 180.873982777346 -2.82735734590066 0.00504204053975935 RAB3D other 0.00182364949775774 1 1 2.99020948363913 -2.82735734590066 7.61314778815733e-07 19.6110154905335 26.8802954454846 0.729568450254059 0.466279511173592 -258.425436439636 55.9691091595245 -4.6172869341741 5.99274061163648e-06 DBP other 0.00684498117633225 0.0925698642279487 1 0.729568450254059 -4.6172869341741 1.43073580294467e-05 191.71994746995 56.8822308818472 3.37047166571544 0.00085914999096283 -154.711918265421 111.167213409222 -1.39170456396983 0.165148904249748 TMEM205 other 0.115717911742165 1 1 3.37047166571544 -1.39170456396983 0.332091288883019 25.1913351659729 133.066823967465 0.189313417235631 0.849988367747112 340.054009879364 250.302666393661 1.35857126405736 0.175408101633684 CAPS other 1 1 1 0.189313417235631 1.35857126405736 0.0339048207745637 15.1401062168497 29.3568125206496 0.515727182785942 0.606463903929613 -114.653750761244 57.3731900437655 -1.99838549458003 0.0466701826095704 PLPPR2 other 1 1 1 0.515727182785942 -1.99838549458003 0.0135307620822649 3.93763596809273 34.3795771735681 0.114534159283381 0.908898559724973 -189.283668289651 71.5838228634112 -2.64422408189658 0.00866173102534062 FAM83E other 1 1 1 0.114534159283381 -2.64422408189658 0.211888289534782 -5.56024533230822 43.2146482508927 -0.12866575472342 0.897716869727724 -149.199578069868 89.9798653682938 -1.65814404655068 0.0984369212106833 RASIP1 other 1 1 1 -0.12866575472342 -1.65814404655068 3.66421783839866e-13 206.771206654027 42.1690084482904 4.90339266353819 1.61919903034549e-06 -326.21258857038 87.8026747056361 -3.71529215555253 0.000246154390673028 BCAT2 other 4.58576862475592e-09 1 0.0176946070036155 4.90339266353819 -3.71529215555253 4.37971395313641e-12 45.3020972649702 22.0427419289631 2.05519337888928 0.0408258408597745 -195.833166397038 38.7697492089146 -5.05118476113352 8.11237513246743e-07 MIER2 other 5.26003645771683e-08 0.0127169592576559 1 2.05519337888928 -5.05118476113352 0.000406143512857094 -3.78114925255802 40.6524860231589 -0.0930115135001577 0.925962635031584 -312.296461615654 84.6450305001551 -3.68948371535033 0.000271188966592743 PLEKHA4 other 1 1 1 -0.0930115135001577 -3.68948371535033 2.58788911614662e-22 1584.08926654832 186.745544618058 8.48260808464364 1.44914866948126e-15 -1401.07073060313 431.33707546677 -3.24820380693444 0.00130771663720547 PPP2R1A other 3.88493914115931e-18 1 2.13474090501285e-11 8.48260808464364 -3.24820380693444 1.51685798489728e-21 582.593050233349 87.1543139751246 6.68461518037571 1.32301402522958e-10 -842.572710077525 194.678713535234 -4.32801663200343 2.12125701203381e-05 TNPO2 other 2.25814648211658e-17 0.323682607466239 1.76265158581337e-06 6.68461518037571 -4.32801663200343 3.65277533971012e-22 559.317132480155 65.0302049825138 8.60088219974936 6.55965308563588e-16 -284.883624060577 145.259552505247 -1.96120405954223 0.0508828729673052 WDR83OS other 5.47587551175943e-18 1 9.70500674019829e-12 8.60088219974936 -1.96120405954223 1.1036716677085e-22 181.600323318235 21.9225389730284 8.28372678646667 5.61434477809661e-15 -132.944552379011 48.9692402803916 -2.71485838084863 0.00705769144999291 GCDH other 1.66179843006869e-18 1 8.2109792379663e-11 8.28372678646667 -2.71485838084863 0.613772670601657 -5.95785221573536 10.2266466040891 -0.58258121614891 0.560656111833709 -24.9951794106005 26.1434600000385 -0.956077711617502 0.339878827571978 LILRB5 other 1 1 1 -0.58258121614891 -0.956077711617502 1.4259316251852e-21 441.871364490336 68.9799058662985 6.4057983109864 6.6182932718942e-10 -724.637887945476 154.083137406732 -4.70290195372033 4.09692862896338e-06 DNASE2 other 2.12363996938833e-17 0.0635146845348192 8.60245759480808e-06 6.4057983109864 -4.70290195372033 0.0411718339086999 16.4168490129384 7.79735391089712 2.10543848599653 0.0361767979893245 38.9689244263793 17.4171393143618 2.23738948876905 0.0260769559699464 MAST1 other 1 1 1 2.10543848599653 2.23738948876905 4.60537855799878e-24 76.6136128613949 9.10026755646424 8.41883080755945 2.17645441457737e-15 -97.974907036738 23.2639779257593 -4.21144257226337 3.44932524924636e-05 LENG1 other 7.01307046812055e-20 0.52309017404821 3.20025857119456e-11 8.41883080755945 -4.21144257226337 2.57200140964563e-24 465.018305657878 50.7667136490631 9.15990561989943 1.27586416585995e-17 -419.576626616008 129.780327706543 -3.23297555207865 0.00137554315168376 PRPF31 essential 3.92333095027344e-20 1 1.92119626095192e-13 9.15990561989943 -3.23297555207865 6.92992462302909e-16 66.0263876528992 12.3241268329606 5.35749011250948 1.79482076962015e-07 -148.078643843026 31.5054708905338 -4.70009302059086 4.12915077207995e-06 TFPT other 9.36648612048612e-12 0.0640100952687833 0.00209006878622267 5.35749011250948 -4.70009302059086 0.0627019824125912 -46.4202010211562 53.994237130918 -0.859725101932688 0.390694910800566 -303.361284750088 128.671212992331 -2.35764688693943 0.0190969515019064 JAK3 og 1 1 1 -0.859725101932688 -2.35764688693943 1.53626680688141e-19 1137.26369819931 130.681217767266 8.70257958741015 3.12695183291334e-16 -247.462014395286 311.420471867368 -0.794623464897578 0.427522804978965 RPL18A essential 2.23142753699525e-15 1 4.64508694779277e-12 8.70257958741015 -0.794623464897578 0.0613807392254376 -11.6001613721841 20.962995457174 -0.553363730669238 0.58046725533616 91.6143045740919 49.9559619091786 1.83390132174112 0.0677571068135793 SLC5A5 other 1 1 1 -0.553363730669238 1.83390132174112 0.0515487647262993 11.3445208220196 4.88355689774935 2.32300371625605 0.0209140255797043 19.447074786508 11.1868848555753 1.73838159930787 0.0832710475875385 KCNN1 other 1 1 1 2.32300371625605 1.73838159930787 0.832795931456295 17.9629767246882 40.7894404699514 0.440383013783213 0.660008208651109 -16.0545811195484 93.4373825092497 -0.171821820008273 0.863704907384621 ARRDC2 other 1 1 1 0.440383013783213 -0.171821820008273 2.5305616575064e-05 498.157579958271 189.788283291728 2.6248068179875 0.00915833479926401 -994.313280647099 434.752725641499 -2.28707773868454 0.0229566934691944 PIK3R2 other 0.199863759709856 1 1 2.6248068179875 -2.28707773868454 0.720464623871972 5.08650832213871 8.22418629134051 0.618481651795077 0.536773562851825 -3.54691001631297 18.839347426141 -0.188271384145258 0.850803787241718 RAB3A other 1 1 1 0.618481651795077 -0.188271384145258 1.55824586079006e-05 633.875869471875 132.097070003198 4.79856116003579 2.63851824701981e-06 596.974930227569 303.04174922578 1.96994286019249 0.0498593091354467 ISYNA1 other 0.125532286545248 1 0.0283825407831921 4.79856116003579 1.96994286019249 5.24966217336809e-10 110.86414254625 20.4439799560794 5.42282582865094 1.29928893440405e-07 -60.1470076239643 46.9705092893051 -1.28052704844014 0.201454726816592 ELL other 5.7604543028368e-06 1 0.00152705428460508 5.42282582865094 -1.28052704844014 3.40157522870039e-05 105.23699587682 23.9485433641397 4.39429631592545 1.59441206379305e-05 38.0526381909548 55.3920045167517 0.68696987088537 0.492686987749295 CRTC1 og 0.2648806630589 1 0.16101967432246 4.39429631592545 0.68696987088537 0.469287422970804 -7.3947794528199 79.7990229270544 -0.0926675438066403 0.926235898262136 194.937269681742 184.571886949357 1.05615905490108 0.291832712177806 COMP other 1 1 1 -0.0926675438066403 1.05615905490108 0.89543889549489 -13.2420189800638 31.1066639548945 -0.425697175346899 0.670667647003236 -36.22452461084 121.954965273962 -0.297031978398457 0.766670478629252 UPK1A other 1 1 1 -0.425697175346899 -0.297031978398457 5.21395831817007e-20 814.785312244985 101.896433982837 7.9962102734844 3.69733058752096e-14 -504.361767169179 235.682297899998 -2.14000699952096 0.0332438875119309 COPE essential 7.62332845699645e-16 1 5.33820590226276e-10 7.9962102734844 -2.14000699952096 1.58278389969079e-29 436.250301722287 44.7349473331634 9.75189036154025 1.83626135086797e-19 -352.56310720268 103.470109520135 -3.40739087682199 0.000755070932584954 DDX49 essential 2.47515746233646e-25 1 2.80268569982979e-15 9.75189036154025 -3.40739087682199 1.10436569121593e-06 4.2534213397246 0.9389707092617 4.52987648897909 8.86758153834491e-06 -6.26026231424554 3.68127358199913 -1.70056970089299 0.090175248540724 ETV2 other 0.00980234987523259 1 0.091424765660336 4.52987648897909 -1.70056970089299 5.23408136293173e-10 22.215512187662 3.33845437736686 6.65443036702033 1.58759443169454e-10 38.685504351017 13.0443359258855 2.96569365974765 0.00329117564710828 ATP4A other 5.74492770395387e-06 1 2.11054803749472e-06 6.65443036702033 2.96569365974765 3.55427630204617e-24 300.397471331014 31.7575227381447 9.45909647323339 1.53306474002096e-18 -119.203140703518 73.4538554685641 -1.62283027818101 0.105784097068019 ARMC6 other 5.41636165668816e-20 1 2.3262724365078e-14 9.45909647323339 -1.62283027818101 1.01444783456662e-20 416.157458305367 44.8466530962179 9.27956557677798 5.85139575931893e-18 -443.098279296085 175.229235452401 -2.52867780968231 0.0120215616570337 TMEM147 other 1.49641200076922e-16 1 8.83677787572344e-14 9.27956557677798 -2.52867780968231 1.04011411269074e-07 15.80825991283 2.76315576657251 5.72108894622286 2.8152532030524e-08 2.10690405591894 10.7964728465596 0.195147441749026 0.845424837535128 GAPDHS other 0.00099580525149011 1 0.000341884348978684 5.72108894622286 0.195147441749026 0.463210782049982 14.1946473822101 45.0606053241349 0.315012354585643 0.752993799429866 126.669891122278 104.223343177503 1.21536967881126 0.225278990053888 TMEM59L other 1 1 1 0.315012354585643 1.21536967881126 0.302475199897378 0.0193706193120632 1.53943222601851 0.0125829633709579 0.989969736907741 -9.46752419768072 6.28517737558461 -1.5063256980556 0.133144025355882 HAMP other 1 1 1 0.0125829633709579 -1.5063256980556 1.61291632732553e-29 605.392330078496 52.1489648897513 11.608904057029 1.41709720782404e-25 -683.639017232715 212.913234337657 -3.21088080484719 0.00148217681799639 USF2 other 2.5219559694062e-25 1 2.21704858164071e-21 11.608904057029 -3.21088080484719 6.62120319720579e-14 1154.50872692858 151.865775518309 7.60216528699976 4.74050593101903e-13 -856.54802499408 620.035958895019 -1.381448950994 0.168274675118128 LSR other 8.48639613785866e-10 1 6.7282000678953e-09 7.60216528699976 -1.381448950994 5.96778694687085e-31 453.663184461178 41.8405879663203 10.8426579671002 5.44922531719704e-23 -229.512773651109 96.1297032165024 -2.38753232322171 0.0176475089112306 KXD1 other 9.36584483441911e-27 1 8.46101215001185e-19 10.8426579671002 -2.38753232322171 8.27680852603119e-13 947.331880592368 143.362832394819 6.60793222879016 2.05807755621088e-10 -291.781831656599 329.379370612204 -0.885853388796862 0.376481910482191 FKBP8 other 1.02342737424376e-08 1 2.7238656456451e-06 6.60793222879016 -0.885853388796862 1.20048675765806e-17 121.152440560746 16.6759520777733 7.26509886786168 4.00556860862222e-12 -86.1595606730006 38.5706245343497 -2.2338129525559 0.0263144529726168 SUGP1 essential 1.68956506272795e-13 1 5.56653869540229e-08 7.26509886786168 -2.2338129525559 0.140731500064827 49.6237223000664 28.2307057203726 1.75779248282325 0.0799076466882343 -61.7722976247271 117.71064141221 -0.524780910915328 0.600162946974035 HPN other 1 1 1 1.75779248282325 -0.524780910915328 1.41497247950833e-11 60.0594033279521 9.08165522363342 6.61326617769611 2.0064072474418e-10 -2.10622704936941 21.013966811775 -0.100229864653122 0.92023621914826 ZNF14 other 1.67023351481163e-07 1 2.65648319561294e-06 6.61326617769611 -0.100229864653122 0.0488132367357747 9.96505954055321 5.01423773934313 1.98735282580731 0.0478861150805532 -21.0463028598219 20.9186013767255 -1.00610468552828 0.315259400842724 SCN1B other 1 1 1 1.98735282580731 -1.00610468552828 0.000215308547850344 19.009014418976 4.5714969016113 4.15815975119134 4.31308962779495e-05 22.836989825512 10.5197237638587 2.17087352654356 0.030812043852679 PBX4 other 1 1 0.419447966303059 4.15815975119134 2.17087352654356 1.1331926716624e-13 360.732456340688 57.6448811412379 6.2578402314135 1.52542086851434e-09 -401.549599157676 156.658922668828 -2.5632092466673 0.010913222627556 ERF other 1.44221431322474e-09 1 1.95787768473816e-05 6.2578402314135 -2.5632092466673 1.82894869927321e-28 573.032552261758 57.2274420934604 10.0132476885113 2.81979166242523e-20 -571.857675852371 155.524467185356 -3.67696277120707 0.000284749914538643 GSK3A other 2.84675865041876e-24 1 4.32133072266667e-16 10.0132476885113 -3.67696277120707 5.35393294579093e-24 535.359406045227 62.6640342246315 8.54332812544635 9.85058207763381e-16 -446.5699709463 144.830209957932 -3.08340346310354 0.00225934621219809 ATP13A1 other 8.14975673008296e-20 1 1.45443844376263e-11 8.54332812544635 -3.08340346310354 6.41656226590753e-25 167.816958236271 18.1828207517929 9.22942378012073 8.20675246243418e-18 -164.781998695287 49.4146410515977 -3.33467966555145 0.000973605077858013 ZNF574 essential 9.82183186042466e-21 1 1.23757827133507e-13 9.22942378012073 -3.33467966555145 0.084461687883783 30.3635282639184 17.0327777751236 1.78265275721875 0.0757663569248615 -27.1800916566207 46.2943195211079 -0.587115048623361 0.557617059053551 GRIK5 other 1 1 1 1.78265275721875 -0.587115048623361 2.14738473805258e-14 427.18216294213 56.652325604615 7.54041706819766 7.47555322786227e-13 -700.112081214279 308.11648195009 -2.27223184161789 0.0238740104554564 SIPA1L3 other 2.79138542099455e-10 1 1.05554811577415e-08 7.54041706819766 -2.27223184161789 0.000268287212539374 24.3325217352906 7.15015376701741 3.40307670690005 0.000768157719737778 -8.92546340817211 16.0278815711193 -0.556871060505896 0.578080259988867 ZNF85 other 1 1 1 3.40307670690005 -0.556871060505896 0.000117663934138737 45.0916496457602 35.1368690665474 1.28331438866562 0.200474246306962 -340.082120712996 100.334922758045 -3.38946910372469 0.000804029390933143 ETHE1 other 0.864006268380747 1 1 1.28331438866562 -3.38946910372469 6.73300503758821e-07 181.041746711002 57.0719025797525 3.17216946566682 0.00168579604430817 -470.092804282061 157.141994546928 -2.99151608478327 0.00302961428906275 CADM4 other 0.00607990354894215 1 1 3.17216946566682 -2.99151608478327 3.78627548668787e-22 278.751669906216 32.7125442810399 8.52124700272182 1.09942796502422e-15 -295.662810436312 90.3325050277002 -3.27305005375029 0.00120149967130942 SMG9 other 5.67486969944778e-18 1 1.62187613400373e-11 8.52124700272182 -3.27305005375029 2.44614181216231e-17 348.518738298067 43.5444389765256 8.00374850359078 3.48096707737082e-14 -234.715450244791 116.329439614706 -2.01767885259476 0.0446030044050076 AVL9 other 3.42435392284602e-13 1 5.02895313667763e-10 8.00374850359078 -2.01767885259476 1.75119761212045e-05 17.4665914230351 4.08065315589832 4.28034208146024 2.61329853726013e-05 -21.5053104294236 17.3978003249511 -1.2360936456192 0.217522420970163 CFAP69 other 0.140551120348787 1 0.259343746837696 4.28034208146024 -1.2360936456192 2.98484442551275e-66 1035.88603925067 44.0223553885225 23.5309090144856 4.65938732969248e-67 -81.7424689494263 403.824812146604 -0.202420620255871 0.839742063737044 CDK6 og 4.76112534313539e-62 1 7.43405248452435e-63 23.5309090144856 -0.202420620255871 1.8011372849639e-26 369.466028583192 32.4503549502045 11.3855774197276 8.95662797993022e-25 -171.597037607087 128.689095304538 -1.33342329589782 0.183520968354911 PMPCB essential 2.7793349444278e-22 1 1.3988461579055e-20 11.3855774197276 -1.33342329589782 2.52600625483165e-21 340.893239863812 34.4351245449553 9.89957911779215 6.65142755681448e-20 -176.931456138457 136.560140287818 -1.29563030446184 0.196213552357389 DNAJC2 other 3.75339269405434e-17 1 1.01800098757046e-15 9.89957911779215 -1.29563030446184 0.00412745257898833 203.827898917912 66.7543866464382 3.05340081989635 0.00249382400773079 -274.004012880447 307.67735784196 -0.890556311333092 0.373978103240482 TFPI2 other 1 1 1 3.05340081989635 -0.890556311333092 2.36838539692776e-24 190.433128363422 16.7560037885374 11.3650683520193 1.20688611814878e-24 -41.7785602770583 77.3455477517481 -0.540154688814833 0.589544002826747 BET1 other 3.61320876155298e-20 1 1.88370785320661e-20 11.3650683520193 -0.540154688814833 0.000135540568510037 2050.92314453113 519.223101036899 3.94998439097836 9.98979134214572e-05 -1100.6251946275 1860.42266212712 -0.591599541885335 0.554615616681749 NAMPT other 0.987819663301152 1 0.937342121633533 3.94998439097836 -0.591599541885335 1.96895369962894e-17 160.506446854711 19.2413019695806 8.34176643079885 3.80304494928037e-15 -107.461421365135 53.1778223628866 -2.0207939436071 0.0442880613709896 TWISTNB essential 2.76106377298966e-13 1 5.5748835911501e-11 8.34176643079885 -2.0207939436071 0.851780939764883 -7.09596893796367 17.3352483009302 -0.409337600176336 0.682614074476469 -30.0239374264581 61.5877965588582 -0.487498158791325 0.626298021638688 PIK3CG other 1 1 1 -0.409337600176336 -0.487498158791325 0.570856974968808 31.9248984783992 45.8560278075295 0.696198515327078 0.486916987363148 -129.228803685039 193.811637536311 -0.666775253167281 0.505498015749442 PON3 other 1 1 1 0.696198515327078 -0.666775253167281 0.000725899424559863 249.941044082392 83.5597720865837 2.99116474161043 0.00304184946350286 -662.94538853644 353.167446780085 -1.87714183337303 0.0616013694772139 PON2 other 1 1 1 2.99116474161043 -1.87714183337303 4.07726349211791e-05 462.729727699738 130.353417581055 3.54980894468692 0.000454874581569225 -665.185438684014 360.267901505394 -1.84636331991973 0.0659379277461229 ITGB8 other 0.315050150035951 1 1 3.54980894468692 -1.84636331991973 7.43918299821564e-06 204.349013449278 52.4936707240174 3.89283147150505 0.000124710925946866 -358.532557147729 186.107632673735 -1.92647959676255 0.0550863698239715 HBP1 other 0.0615741176762308 1 1 3.89283147150505 -1.92647959676255 3.83049653281883e-21 74.9280178508498 7.55491383622911 9.91778589075857 5.56642253366041e-20 -27.5936932820064 26.6345776488968 -1.03601016865193 0.301120953183692 DUS4L other 5.68024330851704e-17 1 8.52386282579419e-16 9.91778589075857 -1.03601016865193 2.2983234607607e-06 44.1952752589074 11.9887633918367 3.68639148296149 0.000274898558469704 -84.2333922969316 33.5079588899771 -2.51383238750862 0.0125249565208309 SP4 other 0.0198529180540509 1 1 3.68639148296149 -2.51383238750862 0.000859391850350519 188.763840086187 71.9974766472954 2.62181188669865 0.00923899054840248 -294.23578193351 191.844980239092 -1.53371634518042 0.126261746945183 WDR91 other 1 1 1 2.62181188669865 -1.53371634518042 4.97206512278507e-13 223.975501836515 29.8552081999754 7.50205794366891 9.18688828336501e-13 -33.3282096923411 83.4447590175434 -0.399404469312856 0.689912121170425 DNAH11 other 6.19320431694108e-09 1 1.29507564130596e-08 7.50205794366891 -0.399404469312856 4.86265768193775e-16 121.201679729039 15.9567784063725 7.59562341735823 4.98715445707267e-13 -148.459058795744 56.2550497204479 -2.63903524276473 0.00879557957313383 CBLL1 essential 6.6015440689987e-12 1 7.07427859735759e-09 7.59562341735823 -2.63903524276473 3.1350551369413e-07 436.707934144657 78.5672862990924 5.5583940176091 6.63348665612032e-08 73.1623463183535 319.157430760587 0.22923591703317 0.818862379230643 DLX5 other 0.00290807714502675 1 0.000791308623208593 5.5583940176091 0.22923591703317 5.19432001794331e-15 1143.82423598627 160.256045936586 7.13747945858397 8.59384836577045e-12 -694.247369479679 436.660294772893 -1.58990267214645 0.11301408900913 MTPN other 6.87416311174618e-11 1 1.18466199722146e-07 7.13747945858397 -1.58990267214645 0.00314704524611398 39.8664207288896 12.4478984790548 3.20266274632381 0.00152601819566836 -10.4441859353338 35.1268888161313 -0.297327383304653 0.766446910378652 STEAP1B other 1 1 1 3.20266274632381 -0.297327383304653 0.0369812890689962 374.501330564803 159.843269409225 2.34292836945182 0.0198512765239338 -31.6118927433506 435.557292744816 -0.0725780357025759 0.942195050284877 PTN other 1 1 1 2.34292836945182 -0.0725780357025759 9.55380914365935e-11 123.924961518727 18.3100681343704 6.7681321887658 8.04572519993723e-11 -5.02327200762278 52.0707739029742 -0.0964700854452992 0.92321853367046 MPP6 other 1.0881788614628e-06 1 1.07852946305159e-06 6.7681321887658 -0.0964700854452992 0.381912764617059 2.77359447829454 27.5617740396134 0.100631928638126 0.91991678473193 -95.072783807384 76.1618150648744 -1.24829986951337 0.212994696139521 ATP6V0A4 other 1 1 1 0.100631928638126 -1.24829986951337 0.000215076525741688 63.6370933441133 34.6627370800478 1.8358934898059 0.0674609126333861 -267.092386241805 95.6797406632527 -2.79152498104947 0.00561638883012016 ZC3HAV1 other 1 1 1 1.8358934898059 -2.79152498104947 5.91665277900576e-14 56.8432500834842 9.80384493221051 5.79805683143007 1.85014094898666e-08 -89.1185709849962 27.0616061983341 -3.29317374334131 0.00112129908476752 TTC26 other 7.59639050296549e-10 1 0.000226642266250866 5.79805683143007 -3.29317374334131 1.63150486456032e-16 667.294385909733 94.894426499234 7.0319660545619 1.6581495375875e-11 -990.562506640939 275.24904863152 -3.5987863048603 0.00037999559896137 OGDH essential 2.23972987806841e-12 1 2.26751949265091e-07 7.0319660545619 -3.5987863048603 0.00298454688806668 79.6986410976501 31.9690186777887 2.49299616922626 0.0132732110572687 -134.114642964616 76.4140271066997 -1.75510502511989 0.080388226010645 ADAP1 other 1 1 1 2.49299616922626 -1.75510502511989 0.0548224398229547 -30.1809196648958 14.8795059383715 -2.02835495949263 0.0435241390531314 -82.0010611990056 42.9518354975968 -1.90913985977604 0.0573240605214378 TFEC other 1 1 1 -2.02835495949263 -1.90913985977604 3.72765550506963e-19 607.000127137566 78.4024453812537 7.74210707568953 1.93301742668554e-13 -872.693756583911 226.118255716858 -3.85945731722204 0.000142006102218349 H2AFV other 5.38348008042157e-15 1 2.76286180796164e-09 7.74210707568953 -3.85945731722204 0.00678785591972177 366.344264083035 183.690745324095 1.99435340869609 0.0471417981558427 -888.040390453167 527.099599384672 -1.68476772035086 0.0932151275458667 CAV2 other 1 1 1 1.99435340869609 -1.68476772035086 0.532068572413319 118.093614510065 584.845955176283 0.201922597676973 0.840132156230682 -1639.65161022258 1678.35399139904 -0.97694027518938 0.329489698675334 CAV1 other 1 1 1 0.201922597676973 -0.97694027518938 8.82728856693416e-07 464.31053087966 136.380718509377 3.40451741239167 0.00076548552166226 -1116.56173523461 391.376774061965 -2.85290750303398 0.00467381039771761 MET other 0.00789336143655252 1 1 3.40451741239167 -2.85290750303398 4.08784194031318e-09 17.7840449221806 4.07270615977796 4.36664080944895 1.80641857131022e-05 -23.2936288021956 10.3858271194657 -2.24282847521479 0.0257285143705389 RNF32 other 4.25871373341827e-05 1 0.181635387345243 4.36664080944895 -2.24282847521479 4.25950510938437e-17 278.876785391865 42.410674109614 6.57562727418772 2.53828430961147e-10 -315.257527354142 108.151659373939 -2.91495783956607 0.00385906239633345 LMBR1 other 5.93263871635054e-13 1 3.3474893475156e-06 6.57562727418772 -2.91495783956607 0.994562773010563 1.91436763148815 24.778646948506 0.077258763784258 0.938475557403362 -2.90797910941384 71.12004156849 -0.0408883212844216 0.967415486001122 WNT2 other 1 1 1 0.077258763784258 -0.0408883212844216 0.000729226384910989 24.1449220401363 7.71982755600506 3.12765043842911 0.00195414158845662 -25.6877937482902 21.5203011796316 -1.19365400762155 0.233657197415641 HOXA1 other 1 1 1 3.12765043842911 -1.19365400762155 4.09052529503349e-12 380.054954670003 81.0073206904313 4.69161245466171 4.34024046373105e-06 -661.863460422141 206.640326083928 -3.20297336422767 0.00152571050493579 DNAJB6 other 4.92090192992529e-08 1 0.0458980041829051 4.69161245466171 -3.20297336422767 0.0446287183088667 0.561308054008628 2.48272356548813 0.226085602848124 0.821305263908106 -16.0049042356951 6.94529023226623 -2.30442554601102 0.0219551106186149 HOXA2 other 1 1 1 0.226085602848124 -2.30442554601102 0.00252006265723873 20.3578399180413 11.4229841466966 1.78218227886875 0.0758390668111956 -73.7574734685296 31.9552048887833 -2.30815210621352 0.021743850660115 HOXA3 other 1 1 1 1.78218227886875 -2.30815210621352 0.0586704935823448 153.462088089582 64.9469847264027 2.36288241457336 0.0188426119902045 26.9560777411714 178.672471217855 0.150868668001484 0.880191969617111 LFNG other 1 1 1 2.36288241457336 0.150868668001484 0.476307284209657 -4.60554139960071 10.5378858391232 -0.437046051732887 0.662425999475519 -35.9064700010507 29.4791883416185 -1.21802776877538 0.224272818096002 HOXA5 other 1 1 1 -0.437046051732887 -1.21802776877538 0.0333973253989859 2.74221140016178 1.86810714354918 1.46790905951567 0.143288588190473 -8.32185181362933 5.16328279451051 -1.61173659178168 0.108183256492487 HOXA6 other 1 1 1 1.46790905951567 -1.61173659178168 2.5010739260596e-09 338.686698840677 55.2571227908133 6.12928581393646 3.11628171863853e-09 -127.031806877963 152.015166262361 -0.835652191826181 0.404089474376215 BRAT1 essential 2.64338503245239e-05 1 3.9536266164367e-05 6.12928581393646 -0.835652191826181 3.17165273476498e-07 137.429116150208 29.9157630882561 4.59386965141992 6.67208659061146e-06 -173.790769362853 81.6114724858966 -2.12948944638741 0.03411513247213 IQCE other 0.00294075641567409 1 0.0695231422741714 4.59386965141992 -2.12948944638741 0.066152646024555 -14.8801609075457 48.0120855317529 -0.309925318651377 0.756856821293338 -298.253210246784 131.313745874231 -2.27130227883715 0.0239160602874547 TSPAN12 other 1 1 1 -0.309925318651377 -2.27130227883715 1.0348986060812e-17 450.0076315523 53.7336599338494 8.37478094933969 2.93200524621526e-15 -154.84160281725 145.362739199644 -1.06520834479176 0.287722851486711 SSBP1 essential 1.45868958527146e-13 1 4.30242449829627e-11 8.37478094933969 -1.06520834479176 0.000200447876168285 32.2257472502015 8.06571175334663 3.99540031130302 8.32816022231695e-05 0.731814812863724 22.2929133724173 0.0328272397886401 0.973836520185636 HOXA13 other 1 1 0.787677393826737 3.99540031130302 0.0328272397886401 0.127317740387262 -47.2976579766361 31.8992960032994 -1.48271792492674 0.139319952142815 -161.209243593247 87.2452906686964 -1.84777014733575 0.0657333456595874 CPED1 other 1 1 1 -1.48271792492674 -1.84777014733575 1.03278184537651e-10 186.021210244035 31.8271425725405 5.84473487747304 1.4482744338953e-08 -173.968196664208 87.9699172742214 -1.97758736230149 0.0489846177281236 HIBADH other 1.17406640182402e-06 1 0.000178499823977595 5.84473487747304 -1.97758736230149 2.81159064906616e-19 594.421354966252 82.5337830359714 7.20215811151151 5.81816214745534e-12 -999.062414419078 228.122585917187 -4.37949802472324 1.69893617346032e-05 TAX1BP1 other 4.06752819200402e-15 0.26009013879504 8.04768188236023e-08 7.20215811151151 -4.37949802472324 0.416419229970274 6.26428954423594 60.5815688037857 0.103402563979896 0.917719674244049 -203.128717369832 166.595459591808 -1.21929323804825 0.223789199515263 CPVL other 1 1 1 0.103402563979896 -1.21929323804825 9.59631751418244e-07 335.872570087064 82.2252379565633 4.08478684202159 5.86724305323796e-05 -478.936379942915 217.603053913534 -2.20096350363366 0.0286110790421861 GRB10 other 0.00855223816863939 1 0.563548695263506 4.08478684202159 -2.20096350363366 4.22291000699376e-10 271.19513708998 42.2024072022534 6.42605848975126 5.89699300191095e-10 -21.951147536139 143.126324642903 -0.153369043681563 0.878221816955054 ABHD11 essential 4.65744744671341e-06 1 7.68024368568882e-06 6.42605848975126 -0.153369043681563 0.575890718303567 -12.282511636666 47.3048972640593 -0.259645667722395 0.795341795722902 -131.51594581428 125.181061666244 -1.05060577106245 0.29441146882433 COBL other 1 1 1 -0.259645667722395 -1.05060577106245 5.44439721458291e-09 116.329751475362 24.2654149677389 4.79405572210588 2.69376614880325e-06 -165.265809885673 66.5072989692943 -2.48492740566678 0.0135593724666522 FKBP14 other 5.63658443625768e-05 1 0.0289606798657837 4.79405572210588 -2.48492740566678 1.63276224433816e-11 86.9112825334959 13.5698925371707 6.40471413428133 6.59322949853181e-10 -53.8174443787311 37.1927247545812 -1.44698848320066 0.149051610031873 PLEKHA8 other 1.92208771403489e-07 1 8.57119834809135e-06 6.40471413428133 -1.44698848320066 0.406636538278769 9.47873506070733 16.6892341012028 0.567955066315727 0.570537474619266 -54.8946399052498 56.6002959632743 -0.969864891534645 0.332981844555727 STX1A other 1 1 1 0.567955066315727 -0.969864891534645 5.38409124694857e-05 46.8425064475457 16.9335054464339 2.76626163411489 0.00605885984517691 -115.961460680052 46.2541407107464 -2.5070503721002 0.0127577813003455 NOD1 other 0.411075366704523 1 1 2.76626163411489 -2.5070503721002 2.23595916783113e-16 932.611924777725 125.14872498367 7.45202897512071 1.21687250958964e-12 -874.816488164218 343.023553985761 -2.55031025712168 0.0113091871292163 GARS essential 3.06035731301046e-12 1 1.71128781023592e-08 7.45202897512071 -2.55031025712168 0.080110847672878 9.45095287563492 4.33940210960706 2.17793895032482 0.0302665616113168 1.5505058667273 11.8939856079632 0.130360496290597 0.896377223252546 CRHR2 other 1 1 1 2.17793895032482 0.130360496290597 0.0507424104448314 62.3178778288648 63.1954149577359 0.98611391143712 0.324950372526236 -292.812712724666 172.083506091979 -1.7015733778004 0.0899738822611812 EPHB6 other 1 1 1 0.98611391143712 -1.7015733778004 0.000865582883671159 25.9812794730177 12.0799581097823 2.15077562661233 0.0323717642465329 -75.8502954182646 33.1102866877574 -2.29083777297254 0.0227350365518035 MINDY4 other 1 1 1 2.15077562661233 -2.29083777297254 3.49821045788635e-12 247.775599438457 45.0463767027123 5.50045569866085 8.76243296187851e-08 -342.678599662328 122.315240161561 -2.80160182173292 0.00545148564140542 CASP2 other 4.22268984371462e-08 1 0.00103904930061955 5.50045569866085 -2.80160182173292 3.85616154346707e-10 1016.41320624156 160.988098051221 6.31359223784463 1.31559651588939e-09 -706.583832332492 502.358315770427 -1.40653356409331 0.160864661214995 CHCHD2 other 4.26530028322892e-06 1 1.69383051420759e-05 6.31359223784463 -1.40653356409331 0.83441839519364 3.28456446610181 7.43969219948734 0.441491983543102 0.659208917382677 -6.10947188914658 24.1078383275745 -0.253422634005247 0.800133785232138 CCL24 other 1 1 1 0.441491983543102 -0.253422634005247 0.0150524574015339 3034.08216876895 1449.39933732673 2.09333762658193 0.0372520570593922 -6074.92994118388 4696.67118133915 -1.29345438644307 0.196959436430812 HSPB1 other 1 1 1 2.09333762658193 -1.29345438644307 0.962830011162591 -12.5567772302714 123.698487141413 -0.101511162508531 0.919221172094332 -151.23834742958 558.89405451969 -0.270602891919387 0.786906319238889 NPTX2 other 1 1 1 -0.101511162508531 -0.270602891919387 1.0326788148973e-26 746.48969055244 65.4743177976945 11.4012595420845 8.50798329562286e-25 -718.123883739529 301.237902370197 -2.38390945524847 0.017828877010582 PDAP1 essential 1.59579857266079e-22 1 1.32886191094333e-20 11.4012595420845 -2.38390945524847 3.96580215039303e-16 387.65863996439 45.2817221916046 8.56104011071078 8.97692940161624e-16 -245.718085881644 208.334679421269 -1.17943919161333 0.23927319791501 BUD31 essential 5.39706014646987e-12 1 1.32562316473667e-11 8.56104011071078 -1.17943919161333 1.71008947572731e-22 398.741577104333 38.063900018003 10.4755838712203 9.51862948557909e-22 -252.579344954977 175.207437693339 -1.44160172810163 0.150582225191999 PTCD1 other 2.57060649991329e-18 1 1.46891490221456e-17 10.4755838712203 -1.44160172810163 0.811859554862692 4.3082915594093 11.9489571807052 0.360557954493819 0.718712886994992 -24.6739827484984 54.2487163884663 -0.454830720266485 0.649597866930276 CYP3A5 other 1 1 1 0.360557954493819 -0.454830720266485 4.14763616972676e-08 328.827946145987 62.2003396870246 5.28659405721192 2.56123724640261e-07 -441.37450094913 274.255307361834 -1.60935627899011 0.108698416634879 ZKSCAN1 other 0.000406883108250195 1 0.00295694840097182 5.28659405721192 -1.60935627899011 3.73993857924786e-11 1621.0891146442 243.403205410525 6.6600976429627 1.52707208832884e-10 -718.195605071746 597.036328536542 -1.20293451293356 0.230055431317565 EIF3B essential 4.33458881334827e-07 1 2.03085317026853e-06 6.6600976429627 -1.20293451293356 1.13913921763531e-11 216.584683881243 30.8382394314228 7.02325060945445 1.7602114137426e-11 -55.2983032416998 75.6421807084031 -0.731051150612275 0.465381846849113 NUDT1 other 1.34851300583668e-07 1 2.405680939162e-07 7.02325060945445 -0.731051150612275 2.88564605783695e-09 1234.68234426415 212.567088894666 5.80843605980782 1.78205607546387e-08 -331.756782427029 581.398264322107 -0.570618804330018 0.568736183865337 PTPRZ1 other 3.03800816969074e-05 1 0.000218551357094889 5.80843605980782 -0.570618804330018 1.85466209784966e-24 410.794990561403 37.8306053588842 10.8588003460254 4.67794334082147e-23 -253.771840749958 166.803659796562 -1.52138053241437 0.129326010921725 TAF6 essential 2.8311416923675e-20 1 7.26578159696391e-19 10.8588003460254 -1.52138053241437 3.382217329457e-18 253.778535130616 40.0779568903043 6.33212256366316 9.99950558712117e-10 -477.863776156071 109.145260453991 -4.37823661942253 1.71029119723996e-05 WASL other 4.80883659902197e-14 0.261794273561521 1.29193612185606e-05 6.33212256366316 -4.37823661942253 4.18627408268484e-12 237.936323660172 34.3506554792357 6.92668947187922 3.08848596722614e-11 -151.697149785789 91.4974034125864 -1.65793939639736 0.0984782644375063 AIMP2 other 5.03441321183679e-08 1 4.18891351734882e-07 6.92668947187922 -1.65793939639736 0.000293509747517918 30.6055241557556 8.09791993966984 3.77943032084402 0.000193188180491554 -22.9187469113012 35.2545130446283 -0.650093986046228 0.516180192178647 TFR2 other 1 1 1 3.77943032084402 -0.650093986046228 5.18963848231167e-14 225.574738950078 35.6740649576829 6.32321377498354 1.04161803616377e-09 -228.804263645095 95.6388115470633 -2.39237878371692 0.0174160151698892 FSCN3 other 6.67439405210104e-10 1 1.34504137009827e-05 6.32321377498354 -2.39237878371692 8.77867821379314e-14 94.6887329944048 12.7115717927615 7.44901846428814 1.25061384000134e-12 -88.7846329063594 55.3401709234373 -1.60434330839332 0.109798847381933 MOSPD3 other 1.12121278146566e-09 1 1.75811293627388e-08 7.44901846428814 -1.60434330839332 0.00400848248601455 470.413865772956 140.826018729979 3.34039029161885 0.000953684543655686 672.959515464798 613.089873859822 1.0976523086706 0.273327085504986 PCOLCE other 1 1 1 3.34039029161885 1.0976523086706 1.42614572039728e-07 13.9758840069301 2.45575578433259 5.69107241692941 3.26226618091097e-08 3.59457070635351 10.691199095345 0.336217731453395 0.736965908082105 FBXO24 other 0.0013522713720807 1 0.000394962566522891 5.69107241692941 0.336217731453395 4.27648945140142e-19 270.51205475579 33.3248934919173 8.11741693402262 1.66114800398287e-14 -199.774948764752 89.7261326696043 -2.22649681671199 0.0268000428171733 RBM28 essential 6.17225722520767e-15 1 2.41265136098472e-10 8.11741693402262 -2.22649681671199 2.99946150359933e-10 105.265780905367 16.8230801388967 6.25722400632106 1.51672004346941e-09 -66.2344888332975 44.5653293245419 -1.48623357747347 0.138375509185709 USP42 other 3.33360151510029e-06 1 1.94686184779733e-05 6.25722400632106 -1.48623357747347 9.15597545257337e-14 615.237990573401 87.0492305805444 7.06770164963304 1.32536445419516e-11 -264.842546835742 234.377067514149 -1.1299848984575 0.259478057030373 IMPDH1 other 1.16903494578457e-09 1 1.81733973959241e-07 7.06770164963304 -1.1299848984575 1.80376796693894e-08 70.6633786815869 15.3510492483632 4.60316278961333 6.39211311486749e-06 -195.574312249709 66.8312072738541 -2.92639202892602 0.00371876540292414 AGFG2 other 0.000180935964763645 1 0.0666939076691853 4.60316278961333 -2.92639202892602 1.66371106488972e-14 210.757659743611 32.625880410246 6.45983057295288 4.78829903190692e-10 -263.53521331729 87.1603923317595 -3.02356616654722 0.00273577466708387 LSM5 essential 2.16831463087077e-10 1 6.25495502538001e-06 6.45983057295288 -3.02356616654722 0.775716985811814 -220.716482462594 421.547451587648 -0.523586328493562 0.600992611746824 -1097.05429478406 1825.28322093527 -0.601032367032847 0.54831895612569 SERPINE1 other 1 1 1 -0.523586328493562 -0.601032367032847 1.70780181735043e-16 336.240226771724 41.9952688857799 8.00662159554784 3.45271989709493e-14 -399.67470588316 181.837796355273 -2.19797376504871 0.0287937098052294 AP1S1 other 2.34344565376827e-12 1 4.98918025130218e-10 8.00662159554784 -2.19797376504871 0.00105042939163097 84.8949011413463 30.1019049147036 2.82025012642567 0.00515046463796853 -145.115936901426 79.6705706594923 -1.82144969842935 0.0696328683889142 C1GALT1 other 1 1 1 2.82025012642567 -1.82144969842935 1.66406227474432e-10 543.306520235049 88.4817378469495 6.14032379398819 2.90705817162078e-09 -647.225741714243 383.122305313356 -1.68934497610333 0.0922992036166342 PLOD3 other 1.87273568399725e-06 1 3.6919638779584e-05 6.14032379398819 -1.68934497610333 8.84351955031089e-12 183.172381492671 26.5592966334566 6.89673314849499 3.72038453197851e-11 -98.2668859125712 70.0655426747456 -1.40249946209281 0.161906449669181 RPA3 essential 1.05114073374995e-07 1 5.03516842557972e-07 6.89673314849499 -1.40249946209281 6.19508662272183e-10 295.831435373425 50.2731257378404 5.88448462337709 1.17517830100123e-08 -374.491256224873 213.868108874974 -1.75103833009436 0.0810707172804283 ZNHIT1 other 6.77308820462178e-06 1 0.000145498825446962 5.88448462337709 -1.75103833009436 4.22574096940202e-07 41.5093020098161 8.71454910828091 4.76321855486159 3.10831177646159e-06 -58.4799811392552 37.0727721845885 -1.57743750178914 0.115861449786521 CLDN15 other 0.0038817656544927 1 0.0332402861374802 4.76321855486159 -1.57743750178914 0.411866594593728 17.3444292691959 13.1427168936671 1.31969891838372 0.188053435622375 10.7430854880899 37.0806468664572 0.289722170348868 0.772251155874104 NOBOX other 1 1 1 1.31969891838372 0.289722170348868 0.577707282182875 13.0262543372429 31.1797216218277 0.417779686914321 0.676437809028613 -70.234511959976 82.2545922819695 -0.853867364866529 0.393929837801199 GLCCI1 other 1 1 1 0.417779686914321 -0.853867364866529 2.66861600569574e-08 211.682886872464 40.1054743725267 5.27815442116979 2.67715229458519e-07 -190.911998931499 102.036510611794 -1.87101653895082 0.0624203120350579 PHF14 other 0.000265020255525644 1 0.0030875597413451 5.27815442116979 -1.87101653895082 1.08551780885364e-07 40.6387545286856 9.1249234430295 4.45359950496126 1.2357757609869e-05 -44.7612854078236 24.667892103122 -1.8145565588135 0.0706976840065222 NRF1 essential 0.0010376464734832 1 0.125962623317395 4.45359950496126 -1.8145565588135 2.08283888064403e-05 289.219990065456 95.0192521763826 3.04380410749373 0.00256482128717265 -707.54131969203 246.604748127876 -2.86913096792904 0.00443888545138627 TMEM106B other 0.16587728845449 1 1 3.04380410749373 -2.86913096792904 8.68883739167713e-12 328.025504044576 49.6686878255859 6.60427159252635 2.13803164553724e-10 -78.3307302231242 128.965827942999 -0.607375856631925 0.544115775992012 EZH2 other 1.03318965424433e-07 1 2.82818826071666e-06 6.60427159252635 -0.607375856631925 0.00075518738472938 35.1613169942496 15.6946282722939 2.24034085957427 0.025876369758089 -86.9933428256655 42.1300614337866 -2.06487576483571 0.0398824194033232 CEP41 other 1 1 1 2.24034085957427 -2.06487576483571 5.69966698292533e-06 47.8448501689269 20.7362468566106 2.30730519846576 0.0218001898937622 -169.776169025119 52.9821375427759 -3.20440391609433 0.00151716041129731 ZNF862 other 0.047626417309324 1 1 2.30730519846576 -3.20440391609433 0.315010706719525 -140.34813432044 114.292403293161 -1.22797430342282 0.220514288651519 -376.265963339878 296.113902979395 -1.27067982811351 0.204924327050945 SFRP4 other 1 1 1 -1.22797430342282 -1.27067982811351 0.0848778163439502 612.01814934347 295.281119064352 2.07266265883424 0.039145523492029 3.10618207056137 792.641371976897 0.00391877358459647 0.996876151589333 MEST other 1 1 1 2.07266265883424 0.00391877358459647 0.121088561384376 -11.896101119532 10.2065731449307 -1.16553332353675 0.24482423526076 -51.3117681731628 26.6128391682146 -1.92808320257869 0.0548856564415057 MEOX2 other 1 1 1 -1.16553332353675 -1.92808320257869 1.39555663986533e-09 86.7544959046144 14.7582324611053 5.87837982178775 1.2098232428507e-08 -62.1559057934373 39.7040387847966 -1.56548068397611 0.1186328841845 ANKMY2 other 1.49617627359962e-05 1 0.000149691429837917 5.87837982178775 -1.56548068397611 0.00182860372691933 15.3085308230915 7.47956754701018 2.04671335967957 0.0416616711495657 -36.5857684963034 19.1106654582405 -1.91441624972445 0.0566317465759632 ACTR3C other 1 1 1 2.04671335967957 -1.91441624972445 0.000356221215260609 39.9932334062794 11.3306078547623 3.52966353781896 0.00048842696331321 -20.2435669746275 29.2508224274812 -0.692068300808139 0.489484789167663 POU6F2 other 1 1 1 3.52966353781896 -0.692068300808139 0.232213297755868 147.184011487077 176.112655837508 0.835737845114766 0.40403593200979 -580.242476879638 472.247201179899 -1.22868378135416 0.220252373992083 TSPAN13 other 1 1 1 0.835737845114766 -1.22868378135416 0.100306992452748 -209.564541203545 101.874679698544 -2.05708171867303 0.040646073012356 -362.690946481909 260.294851292908 -1.39338501964365 0.164657904808575 RARRES2 other 1 1 1 -2.05708171867303 -1.39338501964365 0.317940016631373 -295.874951446143 313.863713079983 -0.942686073973592 0.346678023128289 -1171.57125960712 841.627532950901 -1.39203057616161 0.165050265781876 AGR2 other 1 1 1 -0.942686073973592 -1.39203057616161 0.00310458629303126 357.181576955431 147.129220269625 2.42767260168218 0.0158501260308843 -677.492760363955 394.426533581608 -1.71766527523377 0.0870042451257997 AHR other 1 1 1 2.42767260168218 -1.71766527523377 2.73183362630958e-07 315.971343718769 66.1879533043531 4.77384974068971 2.96066627006708e-06 -170.412411327668 178.235139838291 -0.95611006607496 0.339868749753144 CHCHD3 other 0.00254251755600633 1 0.0317235390837687 4.77384974068971 -0.95611006607496 0.173099079897327 -15.1999944978801 15.6596251355445 -0.970648681964867 0.332582440503653 -73.8828459624116 39.5971825080229 -1.86586118715497 0.0631331444353429 GIMAP2 other 1 1 1 -0.970648681964867 -1.86586118715497 0.0242441323948052 -275.58470265491 108.891189553149 -2.53082644964953 0.0119414766293255 -556.679756298919 274.591196220464 -2.02730372991264 0.043602849324227 TMEM176B other 1 1 1 -2.53082644964953 -2.02730372991264 0.177623837678168 34.3434665604371 45.0298639580379 0.762681996828612 0.446316412293709 -176.438750961108 128.209884872426 -1.37617119878604 0.1699047395797 GLI3 other 1 1 1 0.762681996828612 -1.37617119878604 3.16903654311769e-18 633.731618408144 85.7989286608937 7.38624162677911 1.86992642988287e-12 -929.314017173252 251.22101500856 -3.69918900750236 0.000261860712084292 PSMA2 other 4.50890519354785e-14 1 2.61827098712199e-08 7.38624162677911 -3.69918900750236 2.02245033082259e-16 211.372892721169 28.0413225974289 7.53790738602856 7.19557321375069e-13 -208.588679254834 82.1055651283373 -2.54049380122765 0.0116280459005556 MRPL32 essential 2.7701502181277e-12 1 1.01673449510297e-08 7.53790738602856 -2.54049380122765 3.48824080552166e-18 256.060791366907 33.3096470105238 7.68728624731469 2.77626540473199e-13 -305.282733812948 96.3483907242947 -3.16852966113911 0.00170760514027135 COA1 other 4.95783665688794e-14 1 3.95923209368829e-09 7.68728624731469 -3.16852966113911 5.34592581758048e-11 167.017616189041 38.253076372849 4.36612246714843 1.80127398330403e-05 -447.645075204094 110.645576866284 -4.04575662111716 6.80709400995611e-05 BLVRA other 6.15743735668919e-07 1 0.181172137240719 4.36612246714843 -4.04575662111716 1.2743295228394e-20 230.962962720733 26.4066967428048 8.74637842704292 2.3787416452293e-16 -204.215138434706 76.3815580126049 -2.67361839360498 0.00795930404587205 URGCP other 1.87708738714244e-16 1 3.54004331643025e-12 8.74637842704292 -2.67361839360498 2.44483448324928e-15 421.086127240119 67.7991145860713 6.21079094927631 2.09837302514563e-09 -804.818547838626 204.249975519058 -3.9403605596199 0.000104803571594967 TMEM248 other 3.26067575030956e-11 1 2.67836332929588e-05 6.21079094927631 -3.9403605596199 1.48931929430861e-08 63.8239674504802 11.8547154134481 5.3838464462907 1.63952564223081e-07 -45.6184063766697 35.7132294096302 -1.27735315822121 0.202625866591066 STAG3L4 other 0.00014998934612982 1 0.00191480199756136 5.3838464462907 -1.27735315822121 1.11058896591511e-14 357.504802087843 52.8762802900325 6.76115642263199 8.33397050472602e-11 -246.603133668619 134.318496531969 -1.835958114748 0.0674553223312801 RHEB other 1.45531578093516e-10 1 1.11666870792824e-06 6.76115642263199 -1.835958114748 0.000298287356634435 32.7238168840023 22.696107541599 1.44182507172315 0.150510601197332 -161.758205619676 57.3760529130741 -2.81926339312227 0.00516985201241163 PRKAG2 other 1 1 1 1.44182507172315 -2.81926339312227 1.45161461202756e-28 1000.86450363186 89.5592134857592 11.1754499026614 4.24697476930484e-24 -635.125328151857 259.052002604979 -2.45172908051339 0.0148486092401498 POLD2 essential 2.26030911238812e-24 1 6.61806078300774e-20 11.1754499026614 -2.45172908051339 0.0114064213093657 6.69842258447021 2.25889046482617 2.96535962622946 0.00329258987386858 2.62352529015107 6.53389054908972 0.401525748011891 0.688349532351038 GCK other 1 1 1 2.96535962622946 0.401525748011891 1.00536327933801e-18 246.964965749744 31.1737071785172 7.92221997645297 6.19701626957294e-14 -316.212183183013 105.436544225632 -2.9990757522015 0.00296161123854041 BCL7B other 1.44118826093104e-14 1 8.91626700866155e-10 7.92221997645297 -2.9990757522015 1.33611232434855e-23 833.752155104363 88.8221176383125 9.38676286124406 2.62535064492675e-18 -804.062245413492 256.919936590093 -3.12962184284027 0.00194153548733029 YKT6 essential 2.02701600726919e-19 1 3.97583252359089e-14 9.38676286124406 -3.12962184284027 2.76908590267846e-25 404.94937664025 37.445228982698 10.8144451948034 7.16523856325475e-23 -142.532166420256 126.648252614431 -1.12541755198299 0.261415247434125 TBL2 other 4.24694704893796e-21 1 1.11132850116081e-18 10.8144451948034 -1.12541755198299 2.40129470974498e-05 195.366368483109 48.5091788643887 4.02741033875818 7.3277873211187e-05 -177.315486107551 163.285038869126 -1.08592610404233 0.278476686098315 CLIP2 other 0.190086489223413 1 0.697458797224078 4.02741033875818 -1.08592610404233 9.70837796486986e-23 1482.3078125801 156.772798979915 9.45513394048674 1.60751879350659e-18 -1387.14991413339 527.707398358984 -2.62863457750833 0.00906208817341598 EIF4H other 1.4622758890687e-18 1 2.43844525787014e-14 9.45513394048674 -2.62863457750833 2.76214705172935e-12 473.566155738966 71.8694313849229 6.58925702643465 2.2939283417252e-10 -417.456047828985 241.917162316761 -1.72561567699929 0.0855564753862903 LIMK1 other 3.34661736787529e-08 1 3.03004994658481e-06 6.58925702643465 -1.72561567699929 1.29404829903237e-24 33.1048459012557 3.46128129911964 9.56433269658715 7.76743127159981e-19 -34.1911265962802 12.1678817764534 -2.80994894792986 0.00532015223082166 SPATA6L other 1.97691758643176e-20 1 1.18088257622132e-14 9.56433269658715 -2.80994894792986 0.290956882256881 -12.0028548862159 32.5782160921047 -0.368431925562824 0.712842052834476 -177.757852993928 113.873185051584 -1.56101590478394 0.119700050861253 SLC1A1 other 1 1 1 -0.368431925562824 -1.56101590478394 2.34631080387478e-06 40.9296926662568 11.5346586560526 3.54840952703699 0.000456380554407556 -43.0446549547508 22.1135940528653 -1.94652460616972 0.0526212106498616 LHX2 other 0.0202486622374394 1 1 3.54840952703699 -1.94652460616972 1.63149071218343e-17 100.715357481781 16.4963641792255 6.10530638070029 3.55633920422633e-09 -119.196828352642 32.5379072289375 -3.66332190678307 0.000299592423542788 FKTN other 2.2910048128444e-13 1 4.50090289686884e-05 6.10530638070029 -3.66332190678307 0.0328500997292087 14.7114182885996 8.2960519120972 1.77330354781743 0.0773056764689693 -15.1289309865292 16.3633734409313 -0.924560637886915 0.356020060571479 FSD1L other 1 1 1 1.77330354781743 -0.924560637886915 9.64525319173904e-05 32.5218600852455 11.5778683835574 2.80896785209894 0.00536596404688084 -43.4502619709991 26.8073009505529 -1.62083687765302 0.106323358460811 CNTNAP3 other 0.716352954550459 1 1 2.80896785209894 -1.62083687765302 6.3955223142568e-19 435.747762080078 75.4853176196569 5.7726161301414 2.13162104057507e-08 -649.728420873348 142.140828305745 -4.57101895787313 7.38428788677906e-06 SPIN1 other 9.21083123699265e-15 0.113932177805114 0.000260228296633405 5.7726161301414 -4.57101895787313 9.51715833473395e-14 77.2118195297604 29.6793168997537 2.6015362749269 0.0097870514430926 -314.059326810283 56.0461989867333 -5.60357941284518 5.12759659647957e-08 NMRK1 other 1.21391354559532e-09 0.000812057472984469 1 2.6015362749269 -5.60357941284518 4.94951576951242e-25 518.330783826516 75.9797355887665 6.8219608795684 5.84835588579488e-11 -806.099962260399 146.68397034001 -5.49548775092381 8.98725809135088e-08 TMEM245 other 7.58117330416217e-21 0.00142079563166166 7.87715054257712e-07 6.8219608795684 -5.49548775092381 0.536591008680319 -15.3105019692307 36.2475708414199 -0.422386979701698 0.67307750186326 -75.5915517206263 67.9864705387353 -1.11186168544458 0.267183017050186 PRUNE2 other 1 1 1 -0.422386979701698 -1.11186168544458 6.45425053397015e-15 598.965176989919 112.969971067852 5.30198575186118 2.37300343456213e-07 -837.966382580147 216.058791772863 -3.87841834948831 0.000131919808572734 MEGF9 other 8.51315645430662e-11 1 0.00274390387138419 5.30198575186118 -3.87841834948831 1.03232312603512e-10 236.665314974002 58.4148690288931 4.05145674223704 6.66537326720072e-05 -401.760060617146 113.424279019402 -3.54209931145712 0.000467762676826138 TRIM14 other 1.17364816198933e-06 1 0.636743108215685 4.05145674223704 -3.54209931145712 4.34134633039905e-13 372.197547830967 97.4625893099719 3.81887604737467 0.000166355151859095 -889.352001381506 189.463449227082 -4.69405579286996 4.26422156668054e-06 CORO2A other 5.41800022033801e-09 0.0660954342835484 1 3.81887604737467 -4.69405579286996 2.66649016625973e-07 337.861756092647 120.151448487642 2.81196573445719 0.00528513296972805 -758.435570841639 233.569701167066 -3.24714878279161 0.00131295222179778 TGFBR1 ts 0.00248369751949278 1 1 2.81196573445719 -3.24714878279161 1.60205764106439e-13 287.186104375481 53.5635729220399 5.36159349925127 1.77221250681058e-07 -336.128007828522 104.125483948103 -3.22810511974237 0.00140004096638794 SEC61B essential 2.02884579664394e-09 1 0.002064804791685 5.36159349925127 -3.22810511974237 0.0694743055410944 37.9507022760983 23.5262790413008 1.61311961868152 0.107886665595901 -36.9630752051711 45.3764591669439 -0.814587032213792 0.416026625469359 C5 other 1 1 1 1.61311961868152 -0.814587032213792 0.812236350317658 -34.1336878233929 52.9885729363344 -0.644170732138879 0.520011574349175 -25.3308990974729 104.089839921039 -0.24335611541615 0.807914325228098 OGN other 1 1 1 -0.644170732138879 -0.24335611541615 0.0245901172757224 -139.013676807546 63.3911375476675 -2.19295128917687 0.0291672307064259 -302.619712833034 124.876337173667 -2.42335513422512 0.0160380720975937 ASPN other 1 1 1 -2.19295128917687 -2.42335513422512 0.122427491444522 -25.4187712197486 20.5050493186605 -1.23963472726771 0.216190887012797 -81.3608087616306 40.3935873615498 -2.01420111646427 0.0449837531289809 ECM2 other 1 1 1 -1.23963472726771 -2.01420111646427 6.06615617645364e-06 76.4388069220416 37.7058622131992 2.02723933190642 0.0436130560715714 -221.914024365747 70.6431324248901 -3.14133896315672 0.00186744154996004 TLE4 other 0.0505310809498588 1 1 2.02723933190642 -3.14133896315672 0.542697348256801 5.7430126198284 9.64815030743208 0.595244936783841 0.552174655429806 20.3068215975253 18.4968871313436 1.09785076014843 0.273240561193134 LHX6 other 1 1 1 0.595244936783841 1.09785076014843 3.85215312514909e-13 2080.18166991648 386.507987379107 5.38198882776551 1.59154611317558e-07 -2115.90644487133 748.897073875045 -2.82536348275862 0.00507261052354553 PTGR1 other 4.81673226768642e-09 1 0.00186019909707962 5.38198882776551 -2.82536348275862 1.91441329886316e-05 44.7708284432662 16.25996833588 2.75343884554023 0.00629903507669492 -70.160830236127 31.5379506417353 -2.22464772784826 0.0269347463143834 SUSD1 other 0.15305734324411 1 1 2.75343884554023 -2.22464772784826 0.0965389144678238 67.9459591259065 39.1758908041966 1.73438198165051 0.0839832436575717 -31.0331561661118 72.8058557267411 -0.426245332279139 0.670266210313995 AMBP other 1 1 1 1.73438198165051 -0.426245332279139 0.267412017989684 -35.9563522525367 63.5581775634601 -0.565723462046026 0.572048166850912 -191.474373312617 118.118756483877 -1.6210327556128 0.106169246294643 AKNA other 1 1 1 -0.565723462046026 -1.6210327556128 0.0986110826913272 87.1553767507107 51.5639160273942 1.69023967660656 0.0921319788665296 -46.3325395696203 95.8730259736545 -0.483269815457294 0.629294378403233 TNFSF8 other 1 1 1 1.69023967660656 -0.483269815457294 0.00116588449856911 141.777271539983 57.1487912599643 2.48084462355558 0.0137121023287112 -158.237314825181 106.390237213833 -1.48732927916253 0.138086169816265 DNM1 other 1 1 1 2.48084462355558 -1.48732927916253 0.882241270292631 -110.457970446659 270.681861883051 -0.408073040721077 0.683541087125835 47.1692954960994 503.911051490502 0.093606392153097 0.925490744691451 ENG other 1 1 1 -0.408073040721077 0.093606392153097 0.0802586300262586 117.739904474047 69.0255958141696 1.70574267538416 0.0891975558279427 -81.187958505915 128.500522068614 -0.631810339747599 0.528041467182894 AK1 other 1 1 1 1.70574267538416 -0.631810339747599 5.0639201810603e-36 139.190057532439 10.4980774626289 13.2586235935034 3.42193051321093e-31 -62.9766231373222 36.9052250904337 -1.70644191934888 0.0890842257831961 CDC37L1 other 8.01010894240119e-32 1 5.40596582477063e-27 13.2586235935034 -1.70644191934888 2.28010051038279e-32 232.800090281579 18.4715504371284 12.6031699977736 7.89140712647198e-29 -70.0449796570238 64.7781677642059 -1.08130535448284 0.280548050176226 PLGRKT other 3.58865019329147e-28 1 1.24234422392048e-24 12.6031699977736 -1.08130535448284 1.46630770679122e-18 202.726508804069 28.5406014611684 7.10309168080752 1.07586211532812e-11 -170.143264300677 53.189459111707 -3.19881546348022 0.00154386544152761 TBC1D13 other 2.09799306687687e-14 1 1.47855730509543e-07 7.10309168080752 -3.19881546348022 1.13599259379766e-28 242.275650185768 22.539370147855 10.7489982460235 1.36429952568565e-22 -217.295940506811 78.9364766671535 -2.75279502812204 0.00631882416875451 RIC1 other 1.76976286187737e-24 1 2.11302710538193e-18 10.7489982460235 -2.75279502812204 3.74683353331751e-35 134.540076492961 12.128604722329 11.0927909329314 9.42220553389497e-24 -198.84479607218 41.4509766493094 -4.79710762316847 2.68479721062995e-06 KDM4C other 5.91962229928833e-31 0.0417727598001915 1.46675473546143e-19 11.0927909329314 -4.79710762316847 0.266855141131505 -56.5001149976929 67.5814273492555 -0.836030211461868 0.403896818565211 -359.403978255464 224.036429759588 -1.60422114671769 0.109865465611355 DOCK8 other 1 1 1 -0.836030211461868 -1.60422114671769 3.87928431045914e-08 243.317467540249 50.2712028247028 4.84009639452439 2.21070635733864e-06 -265.584043498857 164.427160870369 -1.61520786525189 0.107460127546937 KANK1 other 0.000381100890659506 1 0.023893314310116 4.84009639452439 -1.61520786525189 0.00306389350247451 9.92281146878704 4.40472369931331 2.25276592725532 0.0252133036574486 -21.3446740014147 12.6742535651133 -1.68409712585894 0.0935135973067165 ELAVL2 other 1 1 1 2.25276592725532 -1.68409712585894 2.88595106832578e-08 252.657761976436 73.3241306578758 3.44576553052248 0.000659106015880466 -443.227053165172 140.119934058477 -3.16319770019444 0.00173670330822543 NCS1 other 0.000286257486467234 1 1 3.44576553052248 -3.16319770019444 1.69979739708906e-38 518.502888211389 39.5657769919023 13.1048327021989 1.24309769418669e-30 -139.206351924505 112.179866392097 -1.24092099947724 0.215724137041804 TESK1 other 2.69417887438616e-34 1 1.96285125912079e-26 13.1048327021989 -1.24092099947724 0.338129683804648 8.2561098314443 5.73603368134895 1.4393412399738 0.151199466457707 2.56400251128833 10.7195453878904 0.239189482250322 0.811138127067261 KCNT1 other 1 1 1 1.4393412399738 0.239189482250322 0.0759338471207385 113.949358974938 134.728337200253 0.845771285706361 0.398440510681222 -528.773869826363 375.461663892764 -1.40832985275798 0.160201131219864 CA9 other 1 1 1 0.845771285706361 -1.40832985275798 1.26628330139146e-14 279.459625265998 48.758993430704 5.73144779256291 2.63075374419007e-08 -313.866635525338 93.176787545508 -3.36850672569114 0.000864631214599557 FUBP3 other 1.65604530155975e-10 1 0.000320083808055606 5.73144779256291 -3.36850672569114 0.50639885791625 -2.75955800389995 8.13664303965938 -0.339151907051765 0.734769062286868 -31.2738078781657 26.8660869741603 -1.1640626306408 0.245465693110446 TYRP1 other 1 1 1 -0.339151907051765 -1.1640626306408 7.37881339741238e-39 563.515684121714 40.9755700373688 13.7524794312269 7.61170535327343e-33 30.0374897299765 114.76577050731 0.261728646069286 0.793733968652886 CREB3 other 1.16983707602576e-34 1 1.20424790394139e-28 13.7524794312269 0.261728646069286 4.10378533226473e-39 499.53555178118 39.6046093883365 12.6130659914624 6.95204558342425e-29 -213.169953688179 110.925937282832 -1.92173227389237 0.0557117996515561 RGP1 essential 6.50696202283895e-35 1 1.09466909756598e-24 12.6130659914624 -1.92173227389237 0.00478571440504217 33.4433974809554 30.6128529334268 1.09246261868125 0.275637164435486 -262.21607553335 103.824988710272 -2.52555843049572 0.0121440498521491 MPDZ other 1 1 1 1.09246261868125 -2.52555843049572 1.13569817343064e-09 253.493712329786 51.0714013393927 4.96351589503497 1.25897639013708e-06 -190.195234020388 140.037892842239 -1.35816977933718 0.175596294169227 DDX58 other 1.22269265351542e-05 1 0.0138638480081895 4.96351589503497 -1.35816977933718 6.56138326683227e-11 787.884416035941 137.672069932481 5.72290673353243 2.77915937209224e-08 -471.212833635187 259.180821854999 -1.81808526673633 0.0701591742299367 EDF1 other 7.52590660705662e-07 1 0.000337612280521765 5.72290673353243 -1.81808526673633 0.0140671289710094 22.4264683636475 20.8420056955688 1.07602256189843 0.282892135578383 -76.4556029598028 40.3207030163342 -1.89618724973198 0.0590188732399975 PIP5K1B other 1 1 1 1.07602256189843 -1.89618724973198 0.291363580342731 9.95448636730105 17.3441592443456 0.573938824422771 0.566490558250659 -70.3024287101199 60.6243954430077 -1.1596392540724 0.247227809448307 GLIS3 other 1 1 1 0.573938824422771 -1.1596392540724 7.51648624799055e-13 491.69902807962 92.9749881507113 5.28850863936204 2.61729651483204e-07 -587.807995597464 268.356050551134 -2.19040336295849 0.029383281846833 BAG1 other 9.30691327226190e-09 1 0.00302009844846469 5.28850863936204 -2.19040336295849 7.0787393358006e-09 535.295810441443 103.375762289421 5.17815587122615 4.35460809343005e-07 -302.844853171956 207.030918658443 -1.46280012248598 0.144672370500297 RAPGEF1 other 7.27694403720302e-05 1 0.00494901209818325 5.17815587122615 -1.46280012248598 0.0570639165338996 113.098630506853 62.0107444807473 1.82385538915706 0.0692793139365802 -89.2304485373629 116.741149648166 -0.764344439011314 0.445329480539986 NPDC1 other 1 1 1 1.82385538915706 -0.764344439011314 4.98620006203321e-07 72.3942474347863 21.0719187056838 3.43557928662942 0.000685844305862509 -88.9088727418174 40.765490064944 -2.18098378310123 0.0300606651630371 APBA1 other 0.00455589099667975 1 1 3.43557928662942 -2.18098378310123 1.06494766518361e-15 396.914974657673 64.4106318560115 6.1622586709748 2.56364564224656e-09 -461.186774891868 125.690784636344 -3.66921708879614 0.000292509899686381 SETX other 1.43341955733713e-11 1 3.26172635063029e-05 6.1622586709748 -3.66921708879614 0.000526545131606771 10.8464501444454 5.30162861763558 2.0458713589189 0.0417674882733078 -49.381773614637 18.8449349425105 -2.62042685556008 0.00929472274891838 SH3GL2 other 1 1 1 2.0458713589189 -2.62042685556008 0.570744222673093 -168.317475575979 176.213961571239 -0.955188079736416 0.340340181090587 22.3368356594755 331.267228393771 0.0674284497376365 0.946290711029387 PTGDS other 1 1 1 -0.955188079736416 0.0674284497376365 0.00274793290989259 318.252537593869 97.9641854350453 3.24866211238887 0.00130625179058302 16.9435503259127 184.426936457503 0.0918713429359435 0.926868385811282 ABCA2 other 1 1 1 3.24866211238887 0.0918713429359435 5.73344549589763e-12 377.997438387808 55.5808041213596 6.80086307428114 7.0646802150137e-11 12.1859660701697 133.305926723564 0.0914135355394939 0.927234126562688 SHB other 6.85777415764316e-08 1 9.48645259272039e-07 6.80086307428114 0.0914135355394939 3.59876948461248e-43 788.215497126709 62.1757564818213 12.6772160360793 4.38908741182642e-29 -529.353087667265 176.11445466167 -3.00573333792616 0.00290447494845739 UBE2R2 other 5.71952434189462e-39 1 6.9132515823678e-25 12.6772160360793 -3.00573333792616 1.10643657294633e-21 106.166659035372 20.3531380107666 5.21623048884209 3.65801305758738e-07 -224.877223507636 38.3891539754651 -5.85783223176414 1.37027946534792e-08 ABHD17B other 1.65013950489215e-17 0.000217586676302596 0.00417708511045903 5.21623048884209 -5.85783223176414 1.23638045318742e-41 295.387941419896 20.754962896099 14.2321594550003 2.07171117600601e-34 -50.054343244938 50.3902225960182 -0.993334434067239 0.321467014324887 EXOSC3 essential 1.96312488357099e-37 1 3.28283352949912e-30 14.2321594550003 -0.993334434067239 6.96944804531994e-25 863.211579192591 141.349992291831 6.10690927672926 3.54011855668264e-09 -1586.12695372789 267.382224104991 -5.93205834470534 9.16966470955629e-09 ZFAND5 other 1.06660432885576e-20 0.000145715141899559 4.48108206904889e-05 6.10690927672926 -5.93205834470534 4.27311520351414e-10 1723.91757911733 316.618759300399 5.44477397020472 1.15961962286435e-07 -421.962926024792 497.611407648623 -0.847976793817299 0.39719647041064 PDLIM1 other 4.71068220035399e-06 1 0.00136649576358335 5.44477397020472 -0.847976793817299 1.40359769678028e-05 59.8319992276668 16.1792597328641 3.69806778650899 0.000262784812055848 -21.5037043695084 25.3713094058786 -0.847559896318393 0.397428282908434 CCNJ other 0.113607197577396 1 1 3.69806778650899 -0.847559896318393 0.235867135136219 -6.87731628435706 97.0935524361259 -0.0708318535247886 0.943583439686705 -234.777683987184 164.009153676576 -1.43149134499018 0.153433244936418 GATA3 other 1 1 1 -0.0708318535247886 -1.43149134499018 0.0767831405790932 29.632634761632 29.1409056778327 1.01687418672692 0.310130398035003 93.0055136030098 41.2742727417265 2.25335317680801 0.0250454962123191 ATRNL1 other 1 1 1 1.01687418672692 2.25335317680801 3.20337439310643e-16 278.784022191403 52.130446705802 5.3478157163072 1.88381366072413e-07 -309.787519347121 81.9610520495395 -3.77969183655521 0.000192854538614478 HPS1 other 4.36908233475785e-12 1 0.00219087528742216 5.3478157163072 -3.77969183655521 3.42835348055664e-08 135.812303568653 35.0971763029615 3.86960769710676 0.00013641049731142 -98.0883121215912 59.0778512624088 -1.66032294718892 0.0979976053915595 PHYH other 0.000337898519043663 1 1 3.86960769710676 -1.66032294718892 0.637782701709691 -76.679732868758 81.03324954354 -0.946274934063421 0.344857602527805 -64.535827013733 127.47589992177 -0.50625904232359 0.61308946656592 RASSF4 other 1 1 1 -0.946274934063421 -0.50625904232359 2.69302573908628e-08 213.851212881639 46.7917439264179 4.57027661157339 7.39773290740273e-06 -101.941031933477 75.4491129903384 -1.35112300056504 0.17777880606656 DNMBP other 0.000267390525633877 1 0.0767884675788403 4.57027661157339 -1.35112300056504 0.000800048471606842 5.67003097483747 25.8491367962145 0.219350882760148 0.826541242501139 -109.623004907249 36.0799026418534 -3.03833982024343 0.00261021545684071 RAB11FIP2 other 1 1 1 0.219350882760148 -3.03833982024343 0.683129095612912 17.8426252531951 115.701281973376 0.154212857013122 0.877557970256992 -109.058476984189 182.331117387814 -0.598134199727546 0.550255523303323 CXCL12 other 1 1 1 0.154212857013122 -0.598134199727546 3.81173788290642e-16 420.348683405456 70.7906918869234 5.93790895668733 8.78399020960798e-09 -219.592269526427 101.499317701698 -2.1634851790019 0.0313747446597065 ERLIN1 other 5.18929995378879e-12 1 0.00010935189411941 5.93790895668733 -2.1634851790019 1.20701979600608e-09 823.809231862811 311.59363890109 2.64385766913655 0.0086762060188589 -1570.47054955796 432.633121695281 -3.6300284717084 0.000338935471393373 EIF3A essential 1.29802908862494e-05 1 1 2.64385766913655 -3.6300284717084 0.842431981311339 -2.08126508771736 4.50756502662115 -0.461727135476838 0.644646065240242 -3.61739662480117 6.4629227727974 -0.559715279289254 0.576134281836297 PKD2L1 other 1 1 1 -0.461727135476838 -0.559715279289254 0.0243685973335252 -3.45377288151069 3.445944671362 -1.00227171672655 0.317106458370169 -15.6739070892741 5.85808696163787 -2.67560164127228 0.00791359141905029 CUBN other 1 1 1 -1.00227171672655 -2.67560164127228 0.000285054936887727 10.9114391701482 8.81538005662885 1.2377729717896 0.216867620091466 -37.993334516965 14.9716906499567 -2.53767830268888 0.0117176804222224 TRDMT1 other 1 1 1 1.2377729717896 -2.53767830268888 1.08327036511376e-27 263.531253753237 32.4174147585715 8.12931122718713 1.53512904682616e-14 -130.75013297188 50.7222130936528 -2.57776869338222 0.0104708029425929 DDX50 other 1.68145226072957e-23 1 2.23069601794309e-10 8.12931122718713 -2.57776869338222 1.11529515735865e-12 158.637796624689 40.1635151702661 3.9497986157878 9.97105806031383e-05 -194.636123766579 63.3085566226078 -3.07440469582707 0.00232375045781584 MAPK8 other 1.37214763209835e-08 1 0.935783798960453 3.9497986157878 -3.07440469582707 3.24477961561928e-10 141.361162201786 44.3903906521662 3.18449917031509 0.00162001143100727 -204.976542716248 61.633970927166 -3.32570722984038 0.00100420085762694 SEC23IP other 3.60073193945271e-06 1 1 3.18449917031509 -3.32570722984038 1.12506805671512e-12 120.745523091423 30.4655625706289 3.96334460627457 9.45088901661253e-05 -143.127412455594 42.3935667446877 -3.37615877705146 0.000842290123085488 ATE1 other 1.38349618934258e-08 1 0.888667094232076 3.96334460627457 -3.37615877705146 8.00918405593503e-15 194.909330819981 33.6016666223863 5.80058522127373 1.83180446960729e-08 -93.2536359022699 46.7575313400645 -1.99440888407992 0.0471054069029874 NSMCE4A other 1.05304751967434e-10 1 0.000224451001660981 5.80058522127373 -1.99440888407992 0.00633808675603498 252.657089412645 156.722186460397 1.6121335154834 0.108088308063427 -306.639586750697 217.736118096598 -1.40830832032496 0.16017758317397 PLEKHA1 other 1 1 1 1.6121335154834 -1.40830832032496 0.0657752091830224 -23.1666743670929 38.5748728770831 -0.60056385515287 0.548630589794633 -129.699237657802 60.5597728770202 -2.14167311890658 0.0331081555514378 PALD1 other 1 1 1 -0.60056385515287 -2.14167311890658 0.00149799739360717 -86.650491241897 139.472285995068 -0.621273901289328 0.534939727201756 -698.601367052139 218.961446468384 -3.19052225092517 0.00158656019487817 UNC5B other 1 1 1 -0.621273901289328 -3.19052225092517 0.153847178833967 -47.4929804380345 56.6600235022788 -0.83820968475462 0.402648917256178 -167.797766411626 88.8224791606183 -1.88913626367257 0.0599372107462082 CDH23 other 1 1 1 -0.83820968475462 -1.88913626367257 0.0975370359526781 -94.6334765482999 115.984122287692 -0.815917512515782 0.415261249703475 -377.166820350617 181.821267413466 -2.07438230805492 0.0389843647793684 VSIR other 1 1 1 -0.815917512515782 -2.07438230805492 0.422837790700447 -783.645290560473 641.246872481733 -1.22206489292904 0.222741069918443 -1149.69385233409 1005.24379354572 -1.14369654377955 0.253755050898502 SPOCK2 other 1 1 1 -1.22206489292904 -1.14369654377955 1.09732038153893e-19 259.662705582478 47.1993938092448 5.50139916270744 8.74567270247263e-08 -238.632420958701 73.7383614359324 -3.23620455230805 0.00136236654214815 MICU1 other 1.59682061921545e-15 1 0.00103714932578623 5.50139916270744 -3.23620455230805 1.55004098141972e-12 197.346792880224 53.4245383093508 3.69393539233793 0.000267248729148723 -271.138073961701 84.6174634435105 -3.20428033325188 0.00151653467919835 PPP3CB other 1.89771517355216e-08 1 1 3.69393539233793 -3.20428033325188 5.64248870633386e-08 76.7651923086705 54.1359711765127 1.41800711505432 0.157346058602162 -283.351541624891 77.6998382734716 -3.64674557786864 0.000318818891329053 CCSER2 other 0.000548788451578031 1 1 1.41800711505432 -3.64674557786864 4.16936360210035e-13 95.0772892747132 29.91922410657 3.17779929506377 0.00165851515370867 -159.959395127415 42.6157099620135 -3.7535311571718 0.000213966688844913 BMPR1A ts 5.20753513902334e-09 1 1 3.17779929506377 -3.7535311571718 1.1858037631162e-12 183.218791751694 31.2072586467701 5.87103128235384 1.2964718451933e-08 -15.1519023189889 44.6797893730348 -0.339122062382267 0.734787372448861 MINPP1 other 1.45699708374087e-08 1 0.000160192061192084 5.87103128235384 -0.339122062382267 0.152274892172371 -864.600171105044 495.116171274024 -1.74625718420845 0.0819120453191428 -1250.0821367215 711.993396948939 -1.75574962082289 0.08027353508285 ACTA2 other 1 1 1 -1.74625718420845 -1.75574962082289 0.462227802389265 -40.8106837830374 288.121651359993 -0.141643932659703 0.887467284177805 -438.833121620376 413.544314134588 -1.06115138480071 0.28957289912712 LIPA other 1 1 1 -0.141643932659703 -1.06115138480071 0.336907726509688 3.72495819255308 26.459809945777 0.140777964777014 0.888149549845423 -42.2110530926135 37.767655116984 -1.11765088306028 0.264702322136925 TLX1 other 1 1 1 0.140777964777014 -1.11765088306028 3.82524080527924e-13 142.896436981672 29.3052380938406 4.87613977146654 1.84235199227698e-06 -97.0800894167434 41.829103372903 -2.32087426190522 0.0210332284293657 TWNK other 4.78461119924327e-09 1 0.0200521590839426 4.87613977146654 -2.32087426190522 1.82879019409535e-10 308.759837548205 101.04904555729 3.0555443235053 0.0024697355324202 -482.722949159869 144.233292314982 -3.34682056695815 0.000932697342198131 LZTS2 other 2.05373138796908e-06 1 1 3.0555443235053 -3.34682056695815 1.67678224227841e-05 -29.2814238421896 67.3212766865316 -0.434950513171828 0.663943241227597 -397.503103420816 96.0916486226603 -4.13670812311442 4.70032682475224e-05 SFXN3 other 0.134779756634338 0.710172379951816 1 -0.434950513171828 -4.13670812311442 0.000688820286448527 14.1607112385244 18.2076499952571 0.777734152524524 0.437401692700675 -68.539581129199 25.9888580802665 -2.63726789832453 0.0088385680770325 KAZALD1 other 1 1 1 0.777734152524524 -2.63726789832453 1.56579972741669e-07 48.5751939211648 78.1025862340517 0.621940914678529 0.534501678949717 -462.672708564192 109.361329630651 -4.23067925496872 3.18732952941272e-05 FBXW4 other 0.00148046364227248 0.483932242450733 1 0.621940914678529 -4.23067925496872 6.23591638946366e-09 435.004469015234 86.1173635953851 5.05129802926927 8.0563763428462e-07 -12.3396573349097 120.583835199192 -0.102332599676614 0.918568080699614 NPM3 other 6.43733648884334e-05 1 0.00899091599861636 5.05129802926927 -0.102332599676614 2.32477673433679e-16 273.589238423397 72.9265852015167 3.75157067436234 0.00021477992796994 -437.70160105545 104.872052168498 -4.17367250859357 4.03761264244487e-05 TNKS2 other 3.18052705024616e-12 0.611456058571851 1 3.75157067436234 -4.17367250859357 6.23915750928754e-10 179.849480790323 115.683323487797 1.55467076297556 0.121182985409067 -706.98009196263 162.88618744751 -4.34033175581849 2.00579039668072e-05 GBF1 essential 6.82064698915314e-06 0.306284193573146 1 1.55467076297556 -4.34033175581849 5.74577582355631e-12 252.444434902596 110.572444064807 2.28306823673571 0.0231979742933116 -864.88757189727 182.237379710423 -4.74593946242854 3.35788909509637e-06 ARHGAP21 other 6.87137330739099e-08 0.0521480176468466 1 2.28306823673571 -4.74593946242854 3.38667558940566e-05 5.46202666599771 9.49321740932911 0.575360958301671 0.565524611591963 -43.7563711164348 13.4506395222546 -3.25310711390623 0.00128619934457471 CPEB3 other 0.263822028414701 1 1 0.575360958301671 -3.25310711390623 3.39725174874284e-12 56.1080440902253 15.1650446763442 3.69982715433392 0.000260880443825095 -66.6673434271437 21.3529161794995 -3.12216574385984 0.00198814756019219 FBXL15 other 4.10286093695673e-08 1 1 3.69982715433392 -3.12216574385984 8.17902183380035e-11 177.063589086398 47.6074901072688 3.71923805870546 0.000242524570707325 -175.788089975545 67.0330201771564 -2.62241041073442 0.00922136293179823 CUEDC2 other 9.34207873856676e-07 1 1 3.71923805870546 -2.62241041073442 1.30770112685154e-09 52.3294221919489 32.1456414849135 1.62788545428493 0.104702673833302 -207.29600686074 47.9203963846466 -4.32584082144939 2.13321834614622e-05 SUFU ts 1.40447101023856e-05 0.325486455254991 1 1.62788545428493 -4.32584082144939 5.5954806845792e-12 38.8423933124644 11.7594778641608 3.30307125547162 0.00108491697721517 -77.7286307164327 19.4659438725235 -3.99305737371142 8.40626588824841e-05 ANKRD26 other 6.69499263909901e-08 1 1 3.30307125547162 -3.99305737371142 4.483182546227e-17 146.781069225335 27.9734523441018 5.24715603279064 3.11972037299896e-07 -172.263538978601 46.3055978795243 -3.72014501198729 0.000242032453670931 ACBD5 other 6.24059010434799e-13 1 0.00358050307209091 5.24715603279064 -3.72014501198729 3.67711606528714e-09 119.304996707543 36.6044976905627 3.25929883579038 0.00125841601798071 -142.323660107845 51.0110206270971 -2.79005709664713 0.00564119430855992 LHPP other 3.84221857661853e-05 1 1 3.25929883579038 -2.79005709664713 1.39033284528476e-26 354.107276782431 73.359100450322 4.82703951668858 2.38012311450149e-06 -798.940396814655 125.125749746337 -6.38509977709877 7.96388831190053e-10 LARP4B other 2.14667391311967e-22 1.26856776920264e-05 0.0256767681592421 4.82703951668858 -6.38509977709877 3.43637826414701e-21 500.634224651356 89.8134186071264 5.57415843217477 6.27881504528661e-08 -634.685578891395 153.19123696328 -4.14309324392706 4.65378056255681e-05 GTPBP4 essential 5.09992898182057e-17 0.703372394224837 0.000749941669009032 5.57415843217477 -4.14309324392706 2.6268603958082e-08 78.5173230471215 25.4298135328487 3.0876090752965 0.00222553512535709 -88.3829260770885 35.1195835108525 -2.51662796769149 0.0124219045610444 EDRF1 other 0.000260952311719587 1 1 3.0876090752965 -2.51662796769149 1.1504425202056e-20 535.459605256182 66.0742653934559 8.1039055382251 1.79649008894004e-14 -64.5889932394335 91.2511874460352 -0.7078153725685 0.479663760022347 BCCIP other 1.69563723053103e-16 1 2.60778501310536e-10 8.1039055382251 -0.7078153725685 0.0536065289321393 90.9167632911892 39.1887501035689 2.31997098787056 0.0210828107330222 42.2526278338743 59.4325454039645 0.710934178347606 0.477734199155611 NEURL1 other 1 1 1 2.31997098787056 0.710934178347606 0.0100469036104645 441.197834460878 284.990062418565 1.54811655787805 0.122756928471982 -561.484054120245 432.207834636388 -1.29910660826548 0.195007461426193 SH3PXD2A other 1 1 1 1.54811655787805 -1.29910660826548 9.92617949401205e-13 362.685926656689 99.7815715796647 3.63479869994956 0.000335020907546055 -600.100683147985 170.257843251692 -3.52465808145388 0.000500588172094309 PITRM1 other 1.22360014622687e-08 1 1 3.63479869994956 -3.52465808145388 2.23768004688032e-08 81.2239955487024 34.0840412999809 2.38305061403467 0.0178541539435363 -170.913927713341 51.6050690990001 -3.31196005930069 0.00105137755899882 STN1 other 0.000223074323873499 1 1 2.38305061403467 -3.31196005930069 0.00940731379770186 43.5221775013213 39.5332055152618 1.10090180986006 0.271909120328181 -129.406984061329 68.0651072967239 -1.90122353729923 0.0583256447842194 MAP3K8 other 1 1 1 1.10090180986006 -1.90122353729923 0.196278106866472 -6.9695145104425 173.247186930462 -0.0402287311784168 0.967940836321712 -393.479644697587 263.783507365115 -1.4916764456883 0.136964526645591 DKK1 other 1 1 1 -0.0402287311784168 -1.4916764456883 0.0206862725683411 6.96423999695823 12.0315885484705 0.578829634083816 0.563183134269573 -30.7749901775644 16.5656358720276 -1.85776087409542 0.0642835139803477 EBF3 other 1 1 1 0.578829634083816 -1.85776087409542 1.73945601933331e-08 700.080474265218 135.747093437776 5.15724098789728 4.83257170612948e-07 64.1851852321245 186.902744514327 0.343414888844526 0.731551648019617 GLRX3 essential 0.000174590789316138 1 0.0054675716283149 5.15724098789728 0.343414888844526 8.33747974291043e-12 177.338846282094 71.0156318155774 2.49718043405754 0.0131144620379178 -533.038123819051 122.001313028248 -4.36911792658846 1.78058958810681e-05 FAM208B other 9.91576465824338e-08 0.272376789292698 1 2.49718043405754 -4.36911792658846 9.73754523069088e-10 306.74247876062 78.3899796112581 3.91303174566161 0.000115233551621608 -254.651423177302 111.800548361748 -2.27772964362695 0.0235188249880372 XPNPEP1 other 1.05233651308076e-05 1 1 3.91303174566161 -2.27772964362695 5.48980263468689e-11 335.255334038793 86.6988772023669 3.86689360758689 0.000138076686967743 -350.874522041049 122.989217477991 -2.85288848271466 0.00466637882849429 SMC3 essential 6.31986079305155e-07 1 1 3.86689360758689 -2.85288848271466 6.1464051440401e-10 146.01016136292 43.1633853353041 3.38273192032266 0.000824002786659626 -182.75775588488 61.17650824033 -2.98738455563566 0.0030724376012661 SHOC2 other 6.72232330603665e-06 1 1 3.38273192032266 -2.98738455563566 6.39508507883247e-18 336.99085065196 55.6297141014818 6.05774910216524 4.65476901861825e-09 -179.964915933136 82.7710300095613 -2.17425004753894 0.0305614140838826 TFAM essential 9.05096391207159e-14 1 5.8612851482441e-05 6.05774910216524 -2.17425004753894 8.19520139347234e-15 315.550565057611 97.9184229518152 3.22258626666088 0.00142686175884127 -650.087887872674 146.848772640369 -4.42692081237023 1.39079876658516e-05 CCDC6 other 1.07701336713013e-10 0.213376346769496 1 3.22258626666088 -4.42692081237023 5.97704961921933e-17 204.336585135964 37.4934410469196 5.44992882569129 1.14577703858635e-07 -212.298943295054 62.3423941253791 -3.40537039479254 0.00076239767294899 CUL2 essential 8.29375405162875e-13 1 0.00135110028390102 5.44992882569129 -3.40537039479254 7.76592024789411e-19 412.829916584196 81.6031082991658 5.05899744738542 7.84886908555063e-07 -603.32435238858 135.685949259132 -4.44647626141713 1.28147631435457e-05 CCNY other 1.1162733764323e-14 0.196745058542857 0.00876561699474294 5.05899744738542 -4.44647626141713 8.88117881263246e-08 185.076556239605 44.5332551488292 4.15591799029922 4.35761548287441e-05 -200.528954603768 98.7954907749119 -2.02973792660879 0.043367391074835 UBE2S other 0.0008532148485296 1 0.423603801090221 4.15591799029922 -2.02973792660879 0.0176247749283676 274.115269311482 249.362270848373 1.09926521112795 0.272631602866226 -539.664135105427 381.076059512706 -1.4161585899558 0.157881670838115 ZMIZ1 other 1 1 1 1.09926521112795 -1.4161585899558 0.561691459072348 -3.60680225553201 48.5042340914201 -0.0743605650742564 0.940778143515155 -67.7827211477739 75.7933029413178 -0.894310163527958 0.371946607548696 DNAJC12 other 1 1 1 -0.0743605650742564 -0.894310163527958 8.04299294974428e-07 1123.58144274785 218.447698707187 5.14348033601363 5.19006858443465e-07 579.175230267198 332.638996786633 1.74115252830294 0.082795888578671 PPIF other 0.00721376037662565 1 0.00586062544554361 5.14348033601363 1.74115252830294 1.55988985464445e-06 3.88139719985627 9.63456515703084 0.402861689821447 0.687366431577502 -59.2669425136166 15.0550880625878 -3.93667192561273 0.000105009678681109 PBLD other 0.0136833538049411 1 1 0.402861689821447 -3.93667192561273 2.32071943727215e-07 570.195061721546 209.955197103819 2.71579398646463 0.00703831720504646 -736.902001547546 319.42887870953 -2.30693606828718 0.0218154001746999 TSPAN14 other 0.00217033681773691 1 1 2.71579398646463 -2.30693606828718 2.66124784893441e-18 44.9458602424725 7.58768836957313 5.92352480140155 9.49245705281153e-09 -53.4848542993189 12.8864843653236 -4.15046127268363 4.44247149222148e-05 TBC1D12 other 3.79147981037685e-14 0.671968237913422 0.0001180007336235 5.92352480140155 -4.15046127268363 9.5077865150909e-08 208.609351561989 35.7425775751916 5.83643838005632 1.5191946415184e-08 190.855369138459 60.8145439540757 3.13831785506086 0.00188682002328244 CYP2C18 other 0.000911796726797217 1 0.00018705843621016 5.83643838005632 3.13831785506086 0.151444104806051 -281.34272736014 147.095309697734 -1.91265600472423 0.0568461050988796 -138.497880156269 332.664984920311 -0.416328397740586 0.677499246679077 KRT23 other 1 1 1 -1.91265600472423 -0.416328397740586 3.88095822283606e-20 727.756110294576 92.6626377807395 7.85382466681566 1.04103521297526e-13 -514.048561597731 204.531599866598 -2.51329653673569 0.0125615113157931 NUFIP2 other 5.681722838232e-16 1 1.49346911653431e-09 7.85382466681566 -2.51329653673569 7.60199652040558e-13 500.230733580745 95.5936431686272 5.23288701005294 3.4223668764975e-07 -583.966120825203 198.778608338807 -2.9377714518952 0.00360010130062074 GIT1 other 9.4112716922621e-09 1 0.00391758336352668 5.23288701005294 -2.9377714518952 5.10830941823096e-17 4051.67379306797 600.063632635944 6.75207356804792 9.17739061917674e-11 -2973.98330274914 1162.81524309231 -2.55757165243237 0.01109778647291 RPL19 essential 7.09850676757374e-13 1 1.22811841265823e-06 6.75207356804792 -2.55757165243237 2.1973852621106e-19 137.371767109604 19.7531839050189 6.95441138857115 2.75914534281149e-11 -123.037650815548 38.3084776038509 -3.21176038598778 0.00148214351994883 FBXL20 other 3.18489019890311e-15 1 3.74802303367512e-07 6.95441138857115 -3.21176038598778 0.698988811278833 -10.5012124873996 39.2091233679615 -0.26782574016894 0.789036440339896 -68.4733522326756 81.1085176119141 -0.844219007432796 0.399288918209135 RUNDC3A other 1 1 1 -0.26782574016894 -0.844219007432796 0.00339789788774208 262.927461822413 88.8493117892055 2.95925152967089 0.00335542293969227 -73.5813180307668 183.794876065751 -0.400344773509593 0.689216844297362 UBTF essential 1 1 1 2.95925152967089 -0.400344773509593 0.167681230112946 -13.1947199217497 47.3129067767956 -0.278882039186419 0.780552860951217 369.461210635846 211.064474883224 1.75046611155316 0.0811951524691873 CSF3 other 1 1 1 -0.278882039186419 1.75046611155316 5.78374899200523e-59 1215.67965427858 61.6108169160449 19.731594468795 5.25555587577057e-54 -928.980324265618 274.079483338009 -3.38945590874437 0.000806508509049848 PSMD3 essential 9.21871751835714e-55 1 8.37367717686526e-50 19.731594468795 -3.38945590874437 0.000185864679498075 247.586379187054 86.9142526976606 2.8486280615943 0.0047325809472487 -886.674450449021 382.959525226187 -2.31532157327938 0.0213536641404273 RAPGEFL1 other 1 1 1 2.8486280615943 -2.31532157327938 2.37484378228928e-06 84.7951564510752 20.5859874319538 4.11907161273474 5.05700434909202e-05 -95.1588769719931 44.7533275350462 -2.12629724342787 0.0343823891052077 RGS9 other 0.0204782779346804 1 0.487950349643889 4.11907161273474 -2.12629724342787 0.000995366002812717 187.000422909618 59.3191290131311 3.15244721257156 0.00179957415408888 -140.39268319887 126.327649070818 -1.11133773351681 0.267400782907563 RNF43 other 1 1 1 3.15244721257156 -1.11133773351681 0.28398918366606 -5.27980317602327 5.53485310089086 -0.95391929646217 0.340968359813835 -25.065912693396 16.7568407116081 -1.49586148873706 0.135844860662428 ASPA other 1 1 1 -0.95391929646217 -1.49586148873706 1.71763795743333e-14 105.558540143112 13.9686710706693 7.55680619932111 6.32646129662272e-13 -45.0379490044729 29.7666117151821 -1.5130357944469 0.131431596144251 RAD51C essential 2.23756696714841e-10 1 8.95067744246182e-09 7.55680619932111 -1.5130357944469 0.630864294932469 13.36572619623 20.2129347429869 0.661246195378306 0.50901210737737 -20.9923151280811 43.046021905314 -0.487671431619322 0.626173986497842 SEPT4 other 1 1 1 0.661246195378306 -0.487671431619322 4.44485210879728e-11 379.006222812952 56.9488390140902 6.6552054330586 1.54475869380416e-10 -103.118712124029 121.279814279976 -0.85025453523517 0.395928662139642 MTMR4 other 5.13736006734789e-07 1 2.0540656351514e-06 6.6552054330586 -0.85025453523517 8.42032259319477e-16 230.249100641791 30.3222581607541 7.59340216091825 5.01273940173477e-13 -151.320959695979 64.6221707503841 -2.34162606948761 0.0199219224473594 TRIM37 other 1.13657514362943e-11 1 7.10956829348042e-09 7.59340216091825 -2.34162606948761 6.82966571342643e-05 -32.0697356630825 7.21929592779944 -4.44222483519357 1.29483623043307e-05 -19.0584346267725 21.7431176077112 -0.876527229012154 0.381514106497514 P2RX1 other 0.516391024592172 1 0.131762534808869 -4.44222483519357 -0.876527229012154 1.79885342812808e-15 413.701590395773 56.6546737564776 7.30216172762749 3.15837257264494e-12 -319.752867304575 121.212320266977 -2.6379568232033 0.00882288221266919 DHX40 other 2.40758542820662e-11 1 4.40087634272346e-08 7.30216172762749 -2.6379568232033 9.65678959447488e-08 72.3893681761231 13.8289228972591 5.23463531570277 3.36737729896434e-07 -30.1180802372856 29.8856099577569 -1.00777866939498 0.314480027047577 TUBD1 other 0.000925699850526362 1 0.00385564700731417 5.23463531570277 -1.00777866939498 4.53576089312042e-12 1388.77702455111 204.662216955822 6.78570302427091 7.29608068449439e-11 -389.409472128327 432.737861847576 -0.899873818449215 0.368989284830623 KPNB1 essential 5.44155234347657e-08 1 9.78842184631768e-07 6.78570302427091 -0.899873818449215 3.05905274381902e-06 77.2830461589554 18.4164963031562 4.19640331617859 3.68337075531046e-05 -54.1717418542092 39.1112777818243 -1.3850670427184 0.16717527006486 GOSR2 essential 0.0261457238014212 1 0.360491495822235 4.19640331617859 -1.3850670427184 1.38066473540669e-09 114.604667325104 26.6314861680237 4.30335230268559 2.35475995104898e-05 -186.380728606531 56.3150071635907 -3.30961031515293 0.00106134497926997 PNPO other 1.48090099519722e-05 1 0.234486995925458 4.30335230268559 -3.30961031515293 1.37861295481211e-11 227.848691605513 31.4410871742884 7.24684519789255 4.66426038240559e-12 39.2354445268354 67.9471622569284 0.577440517360747 0.564132179869947 RPS6KB1 other 1.62841762222407e-07 1 6.46792719897751e-08 7.24684519789255 0.577440517360747 8.15145929430683e-10 1523.45907734782 228.229433887736 6.67512095787432 1.37472787156537e-10 1536.76037780415 592.978220006169 2.5915966657058 0.010067187607174 TRIM16L other 8.85493023140551e-06 1 1.83017521541497e-06 6.67512095787432 2.5915966657058 4.55153633538654e-06 539.767000874691 112.888336636833 4.78142398900911 2.86461777326082e-06 1.71023822623182 238.713958593205 0.00716438299758691 0.994288988911143 CDK5RAP3 other 0.0383967605253208 1 0.0307287548537689 4.78142398900911 0.00716438299758691 8.30879671999405e-12 700.593907195038 109.915644203618 6.37392349625131 7.89287901694608e-10 -362.073606779415 232.334798266694 -1.5584131584275 0.12030235881812 CBX1 other 9.88414457810492e-08 1 1.02354855091757e-05 6.37392349625131 -1.5584131584275 1.00727977219097e-06 128.937196387398 27.0648339181377 4.76401210431926 3.09705009917363e-06 -79.8226276660518 62.6801461950854 -1.27349140854924 0.203934937584682 RECQL5 other 0.00896378269272742 1 0.033122950810662 4.76401210431926 -1.27349140854924 2.72531332109556e-14 68.6298546088458 10.9263531538818 6.28113091736046 1.32026869566376e-09 -72.9112377118415 28.5680555128601 -2.55219462448258 0.0112496496518263 PIGL other 3.53391378346461e-10 1 1.69958189192796e-05 6.28113091736046 -2.55219462448258 7.93972602377603e-11 120.364754857853 17.4817207538971 6.88517775522874 3.98677843953443e-11 -8.10516809077383 40.7892062575878 -0.198708649528233 0.842639102707565 GALK1 other 9.075106845176e-07 1 5.39092180593846e-07 6.88517775522874 -0.198708649528233 7.76048141046449e-17 137.445186087601 16.941978616495 8.11269977367235 1.79414161790061e-14 -75.512575731926 36.6762076836139 -2.05889813863343 0.0404703415989278 INTS2 essential 1.07405062720829e-12 1 2.60455538670631e-10 8.11269977367235 -2.05889813863343 2.56139290618263e-07 192.475568582916 38.5870995591034 4.98808075191305 1.09090797096976e-06 -150.433059144901 122.26059920551 -1.23042959156478 0.219603225277946 CAMTA2 other 0.00238824274572469 1 0.0120621694350126 4.98808075191305 -1.23042959156478 2.68922578682051e-13 446.524586186444 63.0753828181027 7.07922118323301 1.28064945889848e-11 -240.455587734635 137.00623587419 -1.75507038931747 0.0803941622448982 MED13 other 3.3817014269268e-09 1 1.75705105760871e-07 7.07922118323301 -1.75507038931747 0.203092917215235 3.20112814333126 24.6217281889227 0.13001232564867 0.896653481740992 -88.9091939829447 54.1003691930961 -1.64341196389267 0.1014616678212 HOXB6 other 1 1 1 0.13001232564867 -1.64341196389267 6.59869881765251e-17 487.000936128419 65.1698850183192 7.47279109041736 1.08588733756074e-12 -666.581082532763 206.486346046555 -3.22820900895053 0.00139896469995831 ENO3 other 9.15173539020227e-13 1 1.52838642761675e-08 7.47279109041736 -3.22820900895053 4.81684153062461e-17 2933.75661659514 393.384688747987 7.45772954695393 1.19394680674479e-12 -3758.07932250153 1189.7650604603 -3.15867346200905 0.00176426396279429 PFN1 essential 6.69926320079271e-13 1 1.67976376240925e-08 7.45772954695393 -3.15867346200905 8.97009358819811e-27 723.117846924178 67.9643870769344 10.6396581801823 2.54764235567858e-22 -571.994200899243 205.553635951342 -2.78270047742986 0.00576983616614585 RNF167 other 1.38659706686366e-22 1 3.94043843152806e-18 10.6396581801823 -2.78270047742986 4.71866074271365e-20 473.044706723891 49.3404634972316 9.587358390957 6.19534551753847e-19 -107.722256284487 149.226854056666 -0.721869109721914 0.470997340495783 SLC25A11 other 6.90151320229298e-16 1 9.42559867038302e-15 9.587358390957 -0.721869109721914 0.0350484671474466 112.049160731712 70.8022600642772 1.58256474623817 0.114678479224312 -210.77956083538 182.398794318458 -1.15559733617192 0.24885626733297 RASD1 other 1 1 1 1.58256474623817 -1.15559733617192 0.00136767934755496 34.2753538794602 10.5983883028065 3.23401567296642 0.00137130001615145 -23.1808166035488 31.4525960143606 -0.737008054691731 0.46175268642921 CHRNE other 1 1 1 3.23401567296642 -0.737008054691731 4.8683187779132e-10 452.076210594736 82.4916602416747 5.48026563255357 9.68413178414413e-08 -244.38007799805 210.871218053739 -1.15890675007042 0.247510616176125 RAI1 other 5.35369016007115e-06 1 0.00114582647269993 5.48026563255357 -1.15890675007042 4.44495798527718e-23 440.766489862264 41.1242904856753 10.7179111093915 1.33046478400303e-22 -36.0836721257808 126.104739698075 -0.286140490929792 0.774987531592052 NUP88 essential 6.71633151575382e-19 1 2.0607569039423e-18 10.7179111093915 -0.286140490929792 6.07747755406202e-28 1312.23083779984 109.347280849598 12.0005804223404 6.52175018460838e-27 -126.302938184982 319.633033800165 -0.395149827548635 0.693042024638713 C1QBP essential 9.44500786676778e-24 1 1.02339303896875e-22 12.0005804223404 -0.395149827548635 0.745169382307772 18.9972413944394 154.581222141444 0.122894884199173 0.902283841067422 -194.154151024971 311.217824910898 -0.623852927063409 0.533262843909958 SLC6A4 other 1 1 1 0.122894884199173 -0.623852927063409 2.17626026225524e-13 524.997416892208 95.1664838136519 5.51662093474232 8.23874560196504e-08 -542.639374021394 191.598343489629 -2.83217153206111 0.00497957985261529 BLMH other 2.74535232083498e-09 1 0.000977691940585191 5.51662093474232 -2.83217153206111 0.00010018238792882 869.298819974759 223.977637558297 3.8811857712737 0.000131489470690632 -27.837886701613 451.332402688788 -0.0616793443939995 0.950865036137286 CPD other 0.742551859328412 1 1 3.8811857712737 -0.0616793443939995 4.60860599134201e-21 247.986582138239 33.9549611040637 7.30339762069586 3.34462803809173e-12 -250.132999938451 68.2031700788658 -3.66746882365164 0.000296421404681103 GOSR1 other 6.82857149737145e-17 1 4.65672561743511e-08 7.30339762069586 -3.66746882365164 2.4846970868253e-13 695.215651378211 93.5868022299012 7.42856508410636 1.43421710164994e-12 -260.36075277781 207.378836767535 -1.25548371683494 0.210384657807353 CCDC47 other 3.12873057173041e-09 1 2.01364081071652e-08 7.42856508410636 -1.25548371683494 2.73310101935194e-05 38.8413881632284 13.5738957649937 2.86147682549604 0.00454300341896817 -113.412477528464 40.6644963446359 -2.78898025853514 0.00565945472086606 MED31 other 0.215067719212804 1 1 2.86147682549604 -2.78898025853514 9.82436057219761e-41 273.646511627906 23.9368807226932 11.4320038102742 5.63135277270693e-25 -284.693023255814 59.3165981315905 -4.79955075347104 2.62653066819657e-06 DRG2 other 1.55932251001921e-36 0.040874070258475 8.80067811318639e-21 11.4320038102742 -4.79955075347104 5.00647624687047e-15 501.896019366155 60.4332071174321 8.30497078188958 4.80945084984844e-15 -45.6358556034193 133.913841434155 -0.340785202744396 0.7335293306201 FTSJ3 essential 6.62807390323182e-11 1 7.0415169892631e-11 8.30497078188958 -0.340785202744396 2.6553943401366e-38 146.537558623751 15.7365834321602 9.31190428058725 4.64875067180049e-18 -211.694243921528 41.0579084706699 -5.15599191012746 4.89556473438551e-07 AKAP10 other 4.20826895024849e-34 0.00769240086713996 7.02844614069516e-14 9.31190428058725 -5.15599191012746 0.0165146018672139 4877.35213748655 1900.65522135649 2.56614249795689 0.0108256145501923 1806.10599785177 4959.94543739129 0.36413827947303 0.716040809278131 ALDH3A1 other 1 1 1 2.56614249795689 0.36413827947303 2.55646227216425e-14 755.881820449492 99.8266786545452 7.57194199623986 5.79789233250678e-13 -383.464273082071 221.205768382711 -1.73351841539066 0.0841409434441411 SMARCD2 other 3.31803238304198e-10 1 8.21039533206284e-09 7.57194199623986 -1.73351841539066 0.521565050832747 -39.1165858601407 37.5081803076373 -1.04288146050572 0.297929203225178 -57.8975257811298 83.0935112699112 -0.696775535132488 0.486538323052369 ICAM2 other 1 1 1 -1.04288146050572 -0.696775535132488 0.000212977420125234 1156.24394593055 285.628318069986 4.04807182195164 6.73757596646114e-05 73.2297601911765 632.499105076204 0.11577844079693 0.907913566987 SYNGR2 other 1 1 0.64316900175838 4.04807182195164 0.11577844079693 4.38386036195813e-14 107.731383258061 16.246542239682 6.63103457146276 1.79907041713708e-10 -23.1961641184145 41.9296605425965 -0.553216120002915 0.58057151496485 B9D1 other 5.65254955070882e-10 1 2.38646690833234e-06 6.63103457146276 -0.553216120002915 3.61988372473558e-17 256.307442144267 38.8047866452581 6.60504706513024 2.1653180758564e-10 -216.399324627995 76.1142841377724 -2.84308427884964 0.00481583639172451 UTP6 other 5.05046177275108e-13 1 2.86341662351251e-06 6.60504706513024 -2.84308427884964 4.34165717236499e-18 172.50680471739 25.9985337914784 6.63525128382173 1.80651342096872e-10 -163.567548234062 50.9382367086433 -3.21109560917147 0.0014848125441282 C17orf75 other 6.16167985902039e-14 1 2.39597875023082e-06 6.63525128382173 -3.21109560917147 0.00806523454173144 218.409639672835 77.0487190667523 2.83469527226809 0.00492968992165107 -80.4313969957051 168.021039718902 -0.478698364980161 0.63253639163718 CYTH1 other 1 1 1 2.83469527226809 -0.478698364980161 4.58943242879488e-16 1118.33579276512 181.542218041098 6.16019681169671 2.66194597155131e-09 -1059.22720618478 355.776132805262 -2.9772295230511 0.00317569862924296 PSMD11 essential 6.23428501127497e-12 1 3.38439810823034e-05 6.16019681169671 -2.9772295230511 0.000129685814244724 2948.18111735459 686.649841760876 4.29357284899993 2.44538927704082e-05 1515.38043599777 1541.15015508215 0.983278904395262 0.326340798298008 LGALS3BP other 0.947614244686197 1 0.24321841749448 4.29357284899993 0.983278904395262 0.233144166651295 -1.42165826423585 1.92649546612693 -0.737950485341125 0.461187806001868 3.86430530362944 3.76586687362736 1.02613964680787 0.305747606822963 CCL7 other 1 1 1 -0.737950485341125 1.02613964680787 0.754965430737316 18.8583515632417 257.911815341547 0.0731193781807474 0.941765460362225 350.636584013927 504.159796266987 0.695486999578684 0.487350532166615 CCL2 other 1 1 1 0.0731193781807474 0.695486999578684 0.534093421078352 17.9662315866099 16.3013213678741 1.10213345171005 0.271388761605576 10.5241617294685 31.9671561862556 0.329217953206403 0.742247134215053 CCL8 other 1 1 1 1.10213345171005 0.329217953206403 1.48674337433139e-17 54.0740554334572 8.64833019605966 6.25254288487902 1.55701176116147e-09 -57.2978058960922 16.7218574857374 -3.42652160173972 0.00070589019607181 PEX12 other 2.08976648696021e-13 1 1.99764608957016e-05 6.25254288487902 -3.42652160173972 0.621821756545497 0.639712309968797 2.09347870917592 0.305573831329107 0.760162872465382 -2.8403743974918 4.07264588295423 -0.697427293981042 0.486131119472642 KRT32 other 1 1 1 0.305573831329107 -0.697427293981042 0.0848690049060807 14.6134036697677 25.5647060829129 0.571624161152985 0.568050419615675 -80.0860540433894 47.5752146192315 -1.6833566529202 0.0934576223619518 DHX58 other 1 1 1 0.571624161152985 -1.6833566529202 3.22337380344872e-05 370.960566245649 112.218059946891 3.30571181163898 0.00107563255054678 -304.877130971424 207.665722808828 -1.46811484749501 0.143237016805169 KAT2A other 0.251713260311311 1 1 3.30571181163898 -1.46811484749501 1.57141844975812e-17 546.681099395674 91.1129781931788 6.00003545308984 6.32336438357671e-09 -664.523175918971 168.609602435705 -3.94119413318923 0.000103332255169097 RAB5C other 2.20768578006519e-13 1 7.91685220823804e-05 6.00003545308984 -3.94119413318923 2.15807072608355e-05 152.988390685109 40.7719491905741 3.75229523538398 0.00021449911652263 -72.3626103544527 76.4099798888236 -0.94703087816199 0.344469838654337 NAGLU other 0.171652945552686 1 1 3.75229523538398 -0.94703087816199 0.000338127310677832 98.8115729038585 30.8096644742051 3.20716160302839 0.00150198389244687 -48.0777428325681 57.7398404930728 -0.832661511046884 0.405771561686245 HSD17B1 other 1 1 1 3.20716160302839 -0.832661511046884 2.6395488349191e-13 280.766250822261 50.3451803176601 5.57682481323389 5.94136655745114e-08 -262.854140102002 94.2738646677788 -2.78819735489046 0.00567697074371733 MLX other 3.32002452456124e-09 1 0.000710943922264604 5.57682481323389 -2.78819735489046 0.373870211165946 30.2131306205193 24.7338122521578 1.22153149350777 0.222954288942148 53.5266784219144 46.3130129979095 1.15575893160591 0.248805269793626 CNTNAP1 other 1 1 1 1.22153149350777 1.15575893160591 0.280506034606042 -27.5545488673792 17.6008438534042 -1.56552430649794 0.118626950598334 -31.661074838515 38.7769609314567 -0.816491908545388 0.414935987762767 ABI3 other 1 1 1 -1.56552430649794 -0.816491908545388 4.40160187036908e-05 71.8857923746303 35.1081464918877 2.04755304844249 0.0415786258690897 -183.898149016937 65.9433072627455 -2.78873105778894 0.00567074535590778 EZH1 other 0.338835311981012 1 1 2.04755304844249 -2.78873105778894 0.0360509122889944 23.3230156237734 11.9228941839221 1.95615387203757 0.0514779556697683 -26.9434914029992 27.0657240303467 -0.995483858949775 0.320392298222271 DLX4 other 1 1 1 1.95615387203757 -0.995483858949775 0.00862058841902536 198.952268557008 67.1262444295429 2.96385221976529 0.0033102977584405 14.4405324701516 150.90520598057 0.0956927388708573 0.923835856040768 PPP1R9B other 1 1 1 2.96385221976529 0.0956927388708573 0.0701711453585203 -17399.6932373733 7677.99946037118 -2.26617536601547 0.024235332863356 -5200.46915323269 17260.7614195095 -0.301288513689478 0.763427263415279 COL1A1 other 1 1 1 -2.26617536601547 -0.301288513689478 0.882874729938797 -1.87181705931258 11.2491478066952 -0.166396343214419 0.867970052587709 9.82404970508513 25.288990636993 0.388471404260572 0.697974488389947 SGCA other 1 1 1 -0.166396343214419 0.388471404260572 1.08766324101673e-09 110.759457314768 22.0856030476313 5.01500715538065 9.66005531639648e-07 -73.0070688531637 41.448174333115 -1.7614061421961 0.0793099489449358 PTGES3L-AARSD1 other 1.17228344116783e-05 1 0.010725559417795 5.01500715538065 -1.7614061421961 1.54922294840115e-08 163.606414603258 30.0808805471095 5.43888382346504 1.19802425211259e-07 -68.1965908405614 67.1271003973191 -1.0159323199857 0.310567761798263 MRPL27 essential 0.000155898305297608 1 0.00141043395201216 5.43888382346504 -1.0159323199857 0.0798477626728039 373.568370251832 207.270014615742 1.80232712842902 0.0726174567181613 -167.917589502493 388.984791644255 -0.431681631543225 0.666319890758822 VAT1 other 1 1 1 1.80232712842902 -0.431681631543225 1.22243118486012e-10 957.647427276148 144.692438401288 6.61850361952033 1.93530544219314e-10 -35.2708072685085 322.888946820724 -0.109235102705735 0.913096859727759 LRRC59 other 1.38464780309106e-06 1 2.5642797109059e-06 6.61850361952033 -0.109235102705735 9.83422013518054e-06 99.541366726021 24.6631718287465 4.03603264889065 7.09868306042959e-05 -33.9895553260643 46.285512030657 -0.734345453574143 0.463380229128705 RND2 other 0.0806189134683845 1 0.676717456150753 4.03603264889065 -0.734345453574143 0.00879994822409717 102.830826051707 38.2765316041331 2.68652413743264 0.0076627348624046 -88.6937212863707 114.6683241458 -0.773480574928408 0.439907254605376 ALOX12 other 1 1 1 2.68652413743264 -0.773480574928408 2.52905117772315e-05 181.536348692717 52.7998658415588 3.43819715825545 0.000677363127375363 -173.163494836883 109.578199931265 -1.58027321990599 0.115206453644602 HDAC5 other 0.199769752528352 1 1 3.43819715825545 -1.58027321990599 0.0645124891119905 201.295139933284 144.111543655194 1.39680094201828 0.163616234268327 -428.141655767228 318.360520647993 -1.34483275406066 0.179803670616972 ABCC3 other 1 1 1 1.39680094201828 -1.34483275406066 7.94494964736302e-06 446.784516860496 110.393789905005 4.04718886130241 6.76796174272104e-05 -342.467680815886 243.873762913482 -1.40428259573533 0.161379739093772 LUC7L3 essential 0.0656411739865132 1 0.645934268725296 4.04718886130241 -1.40428259573533 0.0573131883488761 25.6308741571488 19.1702320214599 1.33701429009605 0.182339196950905 -50.589411036191 39.1046828563324 -1.29369188907765 0.196873396004297 MPP2 other 1 1 1 1.33701429009605 -1.29369188907765 1.56183093363066e-06 188.824758475031 36.9744064212951 5.10690439012104 6.16702112932439e-07 -19.9360280104132 81.9420875000681 -0.243294119281458 0.807960940822531 SMURF2 other 0.0136988191188745 1 0.00693481525992527 5.10690439012104 -0.243294119281458 6.03355859262903e-06 249.331643406955 61.6856566389618 4.04197113222383 6.91156179914692e-05 -135.736263229792 126.248236503415 -1.07515373671078 0.283262195242037 DUSP3 other 0.0502861796553888 1 0.659155648784642 4.04197113222383 -1.07515373671078 1.29294794552961e-09 562.926339976139 111.885828337778 5.03125684762051 8.84778569872705e-07 -502.745741338086 234.043025346482 -2.14809110672626 0.0325865105428419 EFTUD2 essential 1.38901397788246e-05 1 0.00984716448957328 5.03125684762051 -2.14809110672626 0.0738072412719677 32.7885093638923 35.0534457104721 0.935386199539774 0.350431372569844 -123.490179293008 72.71922657659 -1.69817784245745 0.09063486907556 HLF other 1 1 1 0.935386199539774 -1.69817784245745 0.0127625280025918 19.0883531042982 7.44139005902905 2.56515959422626 0.0108555799877527 35.2831402921527 16.7394506529461 2.10778364378063 0.0359749546655951 SLC16A6 other 1 1 1 2.56515959422626 2.10778364378063 3.7119117932333e-05 730.481336783608 170.84572633088 4.27567813647776 2.64601346670084e-05 -219.587676439904 385.397838897272 -0.569768831782254 0.569308249849171 PRKAR1A other 0.287970116919039 1 0.262458075762056 4.27567813647776 -0.569768831782254 0.00286871956272462 68.6002891544488 28.6081646206066 2.39792695771317 0.017159940687273 -144.992220502859 84.4023269761147 -1.71786994147556 0.0869542398075136 EFNB3 other 1 1 1 2.39792695771317 -1.71786994147556 0.00035945998000686 -163.14308958357 46.1629422930286 -3.53407043571846 0.000481266205116013 104.554451863433 104.135459393443 1.00402353312148 0.316266221178295 FAM20A other 1 1 1 -3.53407043571846 1.00402353312148 1.24961393367903e-26 4843.56009209516 426.62080147627 11.3533144078643 1.07368919907774e-24 -1939.73893014124 1321.35926847846 -1.46798753103298 0.143267284362299 YWHAE other 1.9299037591739e-22 1 1.67635094652008e-20 11.3533144078643 -1.46798753103298 0.557138947458581 25.6049817293016 23.7718105701191 1.07711533598904 0.282393744310303 10.0169724982932 51.0588939405157 0.196184674700613 0.844613747826337 MMD other 1 1 1 1.07711533598904 0.196184674700613 6.58876940583171e-13 119.431585884876 16.1890216913327 7.3773195293708 1.94531746512658e-12 -25.1161384851962 48.1998534940271 -0.521083295166211 0.602731160272619 RANGRF other 8.17929834039949e-09 1 2.72247179244464e-08 7.3773195293708 -0.521083295166211 1.06233156665251e-27 428.2165659206 36.7907787391663 11.6392362596211 1.11777470969923e-25 -170.216254028606 114.101233429643 -1.49180029796579 0.136910375981921 DPH1 essential 1.64905729091469e-23 1 1.74954097562123e-21 11.6392362596211 -1.49180029796579 0.00634204512657691 62.5772073982447 22.0847458462992 2.83350362434581 0.00495276957907444 -34.7785680626731 48.5959626363542 -0.71566784925988 0.474817211530722 MAP2K6 other 1 1 1 2.83350362434581 -0.71566784925988 2.08358765020539e-20 128.953289941971 20.424374382364 6.31369595601026 1.09909587575744e-09 -168.991913884834 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679.68032544524 98.4668353319412 6.90263196896673 4.00454718411162e-11 -14.282463511791 223.273349346653 -0.063968510140528 0.949045221045093 ALDOC other 3.73602293152651e-08 1 5.41454824763732e-07 6.90263196896673 -0.063968510140528 6.70086694576216e-19 837.114003974022 101.483226801959 8.24879174967131 8.35790397201973e-15 -338.425991280882 229.304046456109 -1.47588320621136 0.14119938470773 SUPT6H essential 9.64522788173006e-15 1 1.2190838733588e-10 8.24879174967131 -1.47588320621136 3.39883017516053e-06 291.981595444871 64.3286357424232 4.53890545128281 8.66452820899986e-06 -36.7043020647622 145.433597384166 -0.252378423726995 0.800948745220933 RAB34 other 0.0289342412811416 1 0.0894179311168786 4.53890545128281 -0.252378423726995 4.37249109834541e-13 237.659250594551 38.9139486234884 6.10730236846486 3.65850108547543e-09 -177.554556417149 87.9224220338612 -2.01944569212127 0.0444629699555232 PHF12 essential 5.4559943925154e-09 1 4.62836972323497e-05 6.10730236846486 -2.01944569212127 5.74040960100767e-22 296.358123729937 91.2832589758777 3.24657694143295 0.00131549240373055 -766.136008066188 134.037099655634 -5.7158503879488 2.88400558416018e-08 TMEM33 other 8.58937488598778e-18 0.000457403285647804 1 3.24657694143295 -5.7158503879488 2.7757995909963e-20 346.541027370378 63.1524474001421 5.48737288318612 9.96054878840065e-08 -387.738880531824 103.872752303758 -3.73282571157784 0.000234267606145907 SLAIN2 other 4.07098768015517e-16 1 0.00117783489422838 5.48737288318612 -3.73282571157784 2.47645214572774e-20 409.359022034151 97.7465994001529 4.1879617761261 3.90900620645836e-05 -732.287093137569 156.304382622876 -4.68500678515456 4.60888331419822e-06 OCIAD1 other 3.63543174992833e-16 0.0713962114202446 0.381284465377949 4.1879617761261 -4.68500678515456 0.226889004749374 -19.8697078498001 24.9624467001474 -0.795983987005682 0.426799535574963 -67.3974909704858 39.9168855404384 -1.68844563041392 0.0925776452698421 CWH43 other 1 1 1 -0.795983987005682 -1.68844563041392 1.04596839260911e-16 235.026632454433 32.7577548385042 7.17468683715092 9.22607843842999e-12 -102.383715271634 61.2186605536748 -1.67242658277155 0.0957597997872438 DCUN1D4 other 1.4422858165687e-12 1 1.27061552254058e-07 7.17468683715092 -1.67242658277155 3.15783958654903e-23 322.106922126082 35.2102152180207 9.14811000533807 2.68226058635983e-17 -124.878370339034 71.3814736341108 -1.74945071853152 0.0815020766346311 USP46 other 4.77717972653137e-19 1 4.02687781830201e-13 9.14811000533807 -1.74945071853152 0.209183017485486 -17.5821434845462 68.4111670727322 -0.257006922069514 0.797367733091728 -230.034042974248 140.442397783927 -1.63792449149265 0.102593713767667 SULT1E1 other 1 1 1 -0.257006922069514 -1.63792449149265 0.700407683717732 -53.0060734143402 95.8558252097654 -0.552977070494618 0.580733292308758 -163.658651678734 196.783982938106 -0.831666527098442 0.406326714976781 ODAM other 1 1 1 -0.552977070494618 -0.831666527098442 9.05785253472416e-16 141.065769805681 19.4879062232595 7.23863139475259 5.98560709596638e-12 -74.4672300793376 43.6346219103264 -1.70660880784931 0.0891775670085063 CHIC2 other 1.22172314988359e-11 1 8.2780946137215e-08 7.23863139475259 -1.70660880784931 4.78427790519949e-05 52.5714769924649 16.5110512793542 3.18401754697482 0.00163592950211056 -57.6865044488957 36.4703004911806 -1.58173921442862 0.114968355643401 NMU other 0.366954115328801 1 1 3.18401754697482 -1.58173921442862 0.0915155014922162 13.0770039142711 13.8042628445227 0.94731635159061 0.344364023894406 -41.7867233373462 30.4118135145383 -1.37402931651446 0.170625096651628 KIAA1211 other 1 1 1 0.94731635159061 -1.37402931651446 2.28022849829395e-17 168.138582514225 44.8661191928978 3.74756242659029 0.000218380425716277 -289.435051363536 66.7224275215501 -4.3378974973603 2.03407550223242e-05 LAMTOR3 other 3.19528419465931e-13 0.310521966170802 1 3.74756242659029 -4.3378974973603 7.10243390296497e-12 122.329706399019 106.899087145707 1.14434753060407 0.253492999089303 -793.792568018664 156.599165311715 -5.06894507667775 7.43492365910946e-07 NFKB1 other 8.47036267267602e-08 0.0116594472822155 1 1.14434753060407 -5.06894507667775 0.0347241629652967 220.342378793043 99.4968086191436 2.21456729970581 0.0276280923161877 -6.97438501074529 197.707914816429 -0.0352762053922878 0.971885659204613 AREG other 1 1 1 2.21456729970581 -0.0352762053922878 2.54932616134532e-07 219.583480632059 70.5117596285976 3.1141398511207 0.00204334188658645 -179.156760814558 103.294452715466 -1.73442770744004 0.0839835130221281 MANBA other 0.00237775651068678 1 1 3.1141398511207 -1.73442770744004 2.56354242789485e-16 633.517553034181 222.590833781684 2.84610800126447 0.00476390815345974 -1601.87966115347 325.463332268864 -4.92184372963454 1.490771109043e-06 UBE2D3 essential 3.50410614468946e-12 0.0232694462410521 1 2.84610800126447 -4.92184372963454 1.0884261520607e-05 67.1075602058513 38.073998016901 1.76255617222185 0.0791067591591507 -145.274981792255 58.1263575989852 -2.49929615054343 0.0130382187207808 MAPK10 other 0.088848226792715 1 1 1.76255617222185 -2.49929615054343 3.62983004930392e-22 108.472176136984 27.3180340240984 3.97071678149666 9.19496954447133e-05 -226.724432993122 40.5584460473786 -5.59006705356198 5.54923712299213e-08 ELF2 other 5.44184120991644e-18 0.000878555221312115 0.865798332307421 3.97071678149666 -5.59006705356198 4.038005912314e-11 152.61198237299 39.428322836523 3.87061815958409 0.000136203306523793 -143.423183700247 58.5383085434722 -2.45007393053963 0.014917879192683 NDUFC1 other 4.67439564409468e-07 1 1 3.87061815958409 -2.45007393053963 6.22853478642305e-09 85.1235309997514 81.0835193171719 1.04982531242602 0.294733732384628 -518.672504747837 120.467176536382 -4.30550893330844 2.3306227685586e-05 TBC1D9 other 6.43033931350315e-05 0.355256828611387 1 1.04982531242602 -4.30550893330844 7.97307541322923e-27 167.707675876272 23.2712165569081 7.20665700764526 5.70183621365832e-12 -118.345537033129 34.5744459143587 -3.42291926604616 0.000715283703520642 ZNF330 other 1.2330361126559e-22 1 7.88792021797491e-08 7.20665700764526 -3.42291926604616 3.9612711319949e-05 -36.4310036483273 43.6808428090121 -0.8340270312003 0.405003013346933 -262.030954245773 64.8517336886007 -4.04046182487535 6.96021167774648e-05 INPP4B ts 0.306483547482446 1 1 -0.8340270312003 -4.04046182487535 4.73005943958596e-08 208.84297391701 53.6748834341627 3.89088826197779 0.000125971563335004 -74.9759602240067 78.4447909800502 -0.95577997324353 0.340041549716758 GAB1 other 0.000462126807247548 1 1 3.89088826197779 -0.95577997324353 9.0292072455229e-12 -5.38248490174704 31.4689624093812 -0.171041066805001 0.864319111567581 -277.810820237347 45.7110681119564 -6.07753946061657 4.12506128953529e-09 KLHL2 other 1.07248923662321e-07 6.56132248713484e-05 1 -0.171041066805001 -6.07753946061657 0.0377388722861913 165.034231873656 547.475947877464 0.301445629736767 0.763305881014968 -1481.15757062832 795.250571579831 -1.86250425156675 0.0636140937502346 CPE other 1 1 1 0.301445629736767 -1.86250425156675 6.35736543115325e-05 862.203663432963 317.735605332292 2.71358843316052 0.00708730667268987 -627.285139996475 501.507150227568 -1.25079999300475 0.212098332385285 RPL34 essential 0.482396888915909 1 1 2.71358843316052 -1.25079999300475 3.98521516695155e-05 88.295804195803 139.442263759792 0.633206904528634 0.527132523947973 -650.710235219328 213.324307964183 -3.0503332762649 0.00251238701447176 WFS1 other 0.308136836708694 1 1 0.633206904528634 -3.0503332762649 0.0358765995098081 159.193634228038 90.4345285493842 1.76031916991867 0.0794859261222281 -59.078787925169 133.146675938047 -0.443712075490779 0.65760613193108 ANXA10 other 1 1 1 1.76031916991867 -0.443712075490779 9.56745037970291e-13 198.86749611649 44.8500533330046 4.43405261170885 1.34501075964846e-05 -140.165989169727 67.6300960793444 -2.07253866688705 0.0391606495141401 GRPEL1 essential 1.18052770235154e-08 1 0.136653093180284 4.43405261170885 -2.07253866688705 6.1898082922948e-15 147.766995331844 22.643311852488 6.52585612451422 3.34593000447793e-10 -23.4494907871601 35.6275408962479 -0.658184376391516 0.510982549761125 GAR1 essential 8.16869000334145e-11 1 4.39487906088176e-06 6.52585612451422 -0.658184376391516 1.50931436405643e-19 104.546742475772 16.2256886060113 6.44328539850314 5.42843916194503e-10 -52.9888954443132 25.0870496299678 -2.11220116458076 0.0355978973020761 FRG1 other 2.19258097666477e-15 1 7.07922751109251e-06 6.44328539850314 -2.11220116458076 3.34412450654586e-17 375.854405617812 107.962485809465 3.48134264230568 0.000581346303314718 -752.706864266963 157.400724735086 -4.78210545430341 2.85070155687977e-06 CLCN3 other 4.66906663603933e-13 0.0443170064032528 1 3.48134264230568 -4.78210545430341 8.08681293090989e-06 55.3809728618958 15.6102127191825 3.54773979433614 0.000458028413196239 -13.4527517428009 22.7437476840397 -0.591492305036489 0.554685501681025 AADAT other 0.0667647275575921 1 1 3.54773979433614 -0.591492305036489 0.0011042277272834 256.942216004211 128.602343911587 1.99795904327263 0.0467203725000938 -248.181073618939 187.119501528168 -1.32632393519699 0.185849097596935 GALNT7 other 1 1 1 1.99795904327263 -1.32632393519699 1.65525821063052e-19 677.323913542152 123.409307126335 5.48843461902571 9.42497195401321e-08 -495.139793252971 177.771816621753 -2.78525473082433 0.0057315966296282 DHX15 essential 2.40293834437232e-15 1 0.0011160109290747 5.48843461902571 -2.78525473082433 0.0576998480304872 -202.801488815386 227.484065429899 -0.89149755800316 0.373464979540998 -742.592091963208 327.69210447455 -2.26612750756978 0.0242442843464552 SOD3 other 1 1 1 -0.89149755800316 -2.26612750756978 1.02667426419976e-16 41.3796183245645 13.9764906683243 2.96065867366444 0.00334579937595876 -93.0643046891764 20.1332151841795 -4.62242636547717 5.91129874846492e-06 SEPSECS essential 1.41609181261073e-12 0.0913236543650345 1 2.96065867366444 -4.62242636547717 0.254357041701749 -64.6068677792038 49.0547474442394 -1.31703598826276 0.188943234793634 -117.040025015635 71.8350212754077 -1.62928920932474 0.104417922688268 CPZ other 1 1 1 -1.31703598826276 -1.62928920932474 7.23718174026339e-06 696.872320235001 217.917163960447 3.19787715464894 0.00154934029731463 -375.717912960251 323.498664116196 -1.16142029206432 0.246496740432845 TRIM2 other 0.0599455763546016 1 1 3.19787715464894 -1.16142029206432 2.96080037517066e-05 15.0013916689849 40.2651303426571 0.372565332368794 0.709763182277009 -190.10183339327 58.4812439323423 -3.2506462005699 0.00129695721274039 SLC2A9 other 0.232008317398373 1 1 0.372565332368794 -3.2506462005699 2.0051803793781e-16 90.8063432052094 25.6990807594827 3.53344713202253 0.000482071594818014 -177.662722583958 38.1103520468944 -4.66179694077204 4.92399949824072e-06 FBXW7 ts 2.74669608367212e-12 0.0762185882332681 1 3.53344713202253 -4.66179694077204 9.19763741428793e-07 65.3304433038814 13.292568240529 4.91480969830112 1.53780311121161e-06 23.0351440322356 19.597578651001 1.17540765838738 0.240859509478395 NEIL3 other 0.00820705186476912 1 0.0168374062646559 4.91480969830112 1.17540765838738 1.44382618276754e-16 20.4134126578906 7.46770052718557 2.73356069697456 0.00668413050073861 -51.5146824427819 10.7572655549065 -4.78882687982779 2.78375669609597e-06 TBC1D19 other 1.9843947055957e-12 0.0432902003809885 1 2.73356069697456 -4.78882687982779 0.440015229023382 -5.26378896229446 4.96177556616869 -1.06086800825596 0.289694427348556 -8.97539854144999 7.2205313794531 -1.24303850641666 0.214928014598721 CLNK other 1 1 1 -1.06086800825596 -1.24303850641666 1.49619930660068e-67 2129.52736530575 92.1333814697922 23.1135266212275 3.93909421533907e-66 1060.40725648027 249.759810378206 4.24570812603724 2.9934340817808e-05 NSD2 other 2.38733561361204e-63 0.454942111749046 6.28403700173043e-62 23.1135266212275 4.24570812603724 4.32140667858519e-07 719.787798408483 204.929249379118 3.51237219962134 0.000520435809525215 -378.171703296709 301.062911196862 -1.25612185769846 0.210157593169985 SH3D19 other 0.00396661919027334 1 1 3.51237219962134 -1.25612185769846 6.1548255981168e-11 183.97371634071 94.789507832059 1.94086582522046 0.0533269258794323 -535.906712988655 136.544831150674 -3.92476748092571 0.000110517696575704 STIM2 other 7.06881719943714e-07 1 1 1.94086582522046 -3.92476748092571 0.00107953727167911 14.2586014929548 4.98899087088551 2.85801314573743 0.00459387649344087 0.498571217015968 7.27573672299879 0.0685251866577266 0.945418104012789 NKX3-2 other 1 1 1 2.85801314573743 0.0685251866577266 9.4585971976717e-12 344.141331940725 134.780411941292 2.55334827208145 0.011217393002418 -814.056400052441 212.338772744897 -3.8337623860643 0.000156965991084438 MFSD10 other 1.12254631541968e-07 1 1 2.55334827208145 -3.8337623860643 0.037576431742967 16.0650968284506 17.4919932850044 0.918425737232757 0.359206733656713 -36.2420141008951 25.7958861420469 -1.40495325112407 0.161172016481609 GLRB other 1 1 1 0.918425737232757 -1.40495325112407 0.767174028303428 20.5485150446909 44.6552131029087 0.460159377077352 0.64577355526797 47.6131862164927 65.41716923383 0.727839293172441 0.467345012575582 BST1 other 1 1 1 0.460159377077352 0.727839293172441 3.16406711793771e-08 22.3384047850802 52.6457010469266 0.424315838536721 0.671670895159722 -359.619492995895 77.0035823100354 -4.67016575343181 4.73443274915373e-06 RAPGEF2 other 0.000312831315950501 0.0733316288516422 1 0.424315838536721 -4.67016575343181 2.42889104184654e-07 32.8045009242841 48.3257713185085 0.678820017337626 0.497831199860361 -293.49766496778 74.5125410084734 -3.9389029148047 0.000104179658522394 SNX25 other 0.00226834134398049 1 1 0.678820017337626 -3.9389029148047 5.27921530153858e-05 0.689742012452005 10.483052153404 0.0657959153840552 0.947588819645788 -55.8206986541402 16.1092744699537 -3.46512803902213 0.000615951388273169 LRP2BP other 0.403384841190563 1 1 0.0657959153840552 -3.46512803902213 1.6389113754175e-16 113.828551988965 26.0176826309178 4.37504575652323 1.73381938646462e-05 -138.260298997129 39.9812940392086 -3.45812466353744 0.000631486063465381 UFSP2 other 2.2497336450356e-12 1 0.174543597635393 4.37504575652323 -3.45812466353744 0.0132721829539953 103.419940764575 124.18217281197 0.832808272095288 0.405686205098947 -340.346296668719 198.791481940103 -1.71207686238421 0.0880264754552086 KLF3 other 1 1 1 0.832808272095288 -1.71207686238421 8.09089600617378e-06 91.6169555656891 105.445262266017 0.868857960963271 0.385690825612362 -552.773837994799 169.1162673973 -3.26860240296211 0.00121981070957213 KLHL5 other 0.0667867141272314 1 1 0.868857960963271 -3.26860240296211 0.00720884035070327 21.4269715009355 11.7820678653879 1.81860873199359 0.0700789748915328 -15.7185201517388 18.1559066357631 -0.865752422452804 0.387394565263234 FAM149A other 1 1 1 1.81860873199359 -0.865752422452804 3.57546811405375e-07 280.601764471214 51.5085523063459 5.44767328738617 1.14910259212779e-07 195.334450206841 74.1589116635464 2.63399833984969 0.00892557230704863 NCAPG essential 0.00330444763100847 1 0.00135467704585946 5.44767328738617 2.63399833984969 0.00200722305617145 888.332123854896 379.083971534423 2.34336503402975 0.0198338553803058 -387.302301706714 610.198829245485 -0.634714921012904 0.526149836381175 UGDH other 1 1 1 2.34336503402975 -0.634714921012904 0.0140631044910585 60.945301573909 34.6255186538567 1.76012674880527 0.079531334202836 -30.9518081115307 49.8782587464422 -0.620547085833033 0.535426980295353 PPARGC1A other 1 1 1 1.76012674880527 -0.620547085833033 0.841273920261588 0.276105385889636 9.5925134775026 0.0287834243378639 0.977058428167421 -8.57098275937379 17.2431403418842 -0.497066229783826 0.619543878971742 DDX25 other 1 1 1 0.0287834243378639 -0.497066229783826 0.223551445301239 321.212753119599 733.847151628012 0.437710703662201 0.661944656237366 -1535.46727489544 1300.94618392788 -1.18026963287558 0.238927934196518 CRYAB other 1 1 1 0.437710703662201 -1.18026963287558 2.40569362647812e-13 573.499185693307 99.892887790342 5.74114132026079 2.49984306905216e-08 -323.646930328054 192.305091219525 -1.68298680121056 0.0935208526633643 HTATIP2 other 3.03021169191184e-09 1 0.0003043558936571 5.74114132026079 -1.68298680121056 6.62113692862601e-05 758.02428281857 539.214549512673 1.40579345179697 0.160943739457454 -3409.3041606766 1105.9115133748 -3.08280013314335 0.00226458995762054 CTSC other 0.50102143138913 1 1 1.40579345179697 -3.08280013314335 3.78082667417932e-11 237.574955714919 35.7180260299622 6.6514021663915 1.63479086663429e-10 40.5839142507271 68.8947346855438 0.589071348281756 0.556311470284592 CCDC34 other 4.38122195003899e-07 1 2.17214662449698e-06 6.6514021663915 0.589071348281756 0.477972041984946 13.499206281768 21.9300992961453 0.61555609482082 0.538702240531929 -21.6540682404561 38.4982572619731 -0.562468791589821 0.574259922117742 ZBTB16 other 1 1 1 0.61555609482082 -0.562468791589821 5.35120810744428e-23 107.235258008056 11.5526186792097 9.28233338135173 6.40795478347001e-18 -27.5721521052036 22.8703132953743 -1.20558698733613 0.22906031450679 ELP4 other 8.07925400061938e-19 1 9.67344854112633e-14 9.28233338135173 -1.20558698733613 1.29691270426115e-21 333.978014842301 46.3244423022141 7.2095420526269 5.55935090091834e-12 -235.631629723659 80.2578136407029 -2.93593382419476 0.00360971634678061 ZPR1 other 1.93252962061955e-17 1 7.6930297766908e-08 7.2095420526269 -2.93593382419476 7.4804003215154e-12 513.678204984318 93.0960583547377 5.5177223833363 8.02281637130418e-08 -420.460572117155 199.245816736288 -2.11026047625209 0.0357523943106831 MTCH2 other 8.91364502311774e-08 1 0.000953030356747224 5.5177223833363 -2.11026047625209 4.21884650293063e-09 422.751310487465 85.6642600603418 4.93497883702817 1.40435255142378e-06 -277.801137029359 183.230559537908 -1.5161288473383 0.130656642290671 FNBP4 essential 4.39181920955078e-05 1 0.0154113648993246 4.93497883702817 -1.5161288473383 0.033057335341091 -2.10631169486903 2.36340741163687 -0.891218198139706 0.373596907227306 -11.0718144951227 4.27324160472573 -2.59096384414082 0.0100852636928718 TECTA other 1 1 1 -0.891218198139706 -2.59096384414082 5.43278973497215e-10 584.364417678884 161.0055315858 3.6294679563073 0.000338990673977449 -947.175043380622 291.075255275281 -3.25405552761551 0.00128098096612663 SC5D other 5.95542410747647e-06 1 1 3.6294679563073 -3.25405552761551 0.153952585875916 0.411123441891095 4.60828542221751 0.089213970972584 0.92897727541698 14.446597689315 8.36046039997136 1.72796676237644 0.0851249973888845 CRTAM other 1 1 1 0.089213970972584 1.72796676237644 0.193481678407104 7.48059644457802 5.35763129281607 1.39625070030642 0.16387259906298 16.642630237388 9.7703600349314 1.7033794228551 0.0897348400846467 B3GAT1 other 1 1 1 1.39625070030642 1.7033794228551 0.000104365970390599 4217.68196222563 1137.0191062456 3.70942048296118 0.000251650691628669 -290.941455613408 2062.80695330777 -0.141041533308231 0.887941146617923 HSPA8 other 0.771786351038478 1 1 3.70942048296118 -0.141041533308231 0.0130933353219526 25.1971508086782 54.6388531344 0.461158120334234 0.645052355160317 -226.376692612953 98.1398870959006 -2.30667366054479 0.0218218942562565 VWA5A other 1 1 1 0.461158120334234 -2.30667366054479 0.00011168996505636 38.5890960879434 27.6203066209422 1.39712772264029 0.163509696032314 -209.409150384974 60.8704477162802 -3.44024330757413 0.000672126525428346 DNAJC4 other 0.823266732430428 1 1 1.39712772264029 -3.44024330757413 1.42728120630774e-06 70.3387423343229 51.8635982270589 1.35622565226539 0.176147997220316 -351.516903180956 92.9819650933303 -3.78048477280645 0.000192271970460535 SIAE other 0.0125576419083378 1 1 1.35622565226539 -3.78048477280645 8.0304731718741e-07 101.5369253659 21.4798638859541 4.72707489698276 3.67141204340058e-06 -57.0095751215912 49.6354696129557 -1.14856524106928 0.251751823367222 SNX15 other 0.00720333443517107 1 0.0390271100213481 4.72707489698276 -1.14856524106928 0.490386383193162 -33.3184562225096 39.658364907311 -0.840136911856579 0.401566792159717 -106.565048930543 96.3264462323627 -1.10629067196647 0.26957462959884 LPXN other 1 1 1 -0.840136911856579 -1.10629067196647 0.0195259215821626 -167.923307863838 80.1594599005475 -2.09486575972664 0.0371079085783585 -474.582455723854 185.963248426418 -2.55202283106834 0.0112570898149865 DTX4 other 1 1 1 -2.09486575972664 -2.55202283106834 3.39321761031733e-06 132.161878214365 46.1148626563883 2.8659280457828 0.00448391259012316 -334.911794138474 106.014020050397 -3.15912738691793 0.00176161683505162 ATG2A other 0.0288898547342417 1 1 2.8659280457828 -3.15912738691793 0.0685501873470525 112.616141613875 121.784185214754 0.924718931405486 0.355934800390159 -487.382134488612 279.971148334095 -1.74082985832172 0.0828483552228883 EHD1 other 1 1 1 0.924718931405486 -1.74082985832172 1.66363888901279e-13 324.924567600252 60.632322106939 5.35893326050044 1.79595309414816e-07 -518.862151984594 141.313907881049 -3.67169912547706 0.000290393217580005 OSBP other 2.10600046960129e-09 1 0.00209120778282612 5.35893326050044 -3.67169912547706 0.00180537367179984 57.9001294217505 31.231139520285 1.85392304959426 0.064857111231686 -335.583266804761 130.529107463242 -2.570945847456 0.0106863703688606 UNC93B1 other 1 1 1 1.85392304959426 -2.570945847456 8.77742221994269e-20 66.3944091448233 10.0016870263683 6.63832101222346 1.71454065707338e-10 -61.919231816028 17.9786552769245 -3.44404132913662 0.000663492138466832 PUS3 other 1.27922151433445e-15 1 2.27605272226491e-06 6.63832101222346 -3.44404132913662 1.5077364489876e-12 84.7325328473405 18.8363256852217 4.49835781475252 1.01538066408747e-05 -112.361408291317 34.0969651675299 -3.29534924117872 0.00111348185451554 DCPS other 1.84652482907512e-08 1 0.104218671361938 4.49835781475252 -3.29534924117872 1.93244822703294e-45 490.973270112534 29.138248570595 16.8497865931449 7.60421290757976e-44 -140.249070893392 122.025168670899 -1.14934543767477 0.251445939441486 KMT5B other 3.0739453947413e-41 1 1.20960214720871e-39 16.8497865931449 -1.14934543767477 2.48789377977965e-17 233.811582736795 30.5266694366986 7.65925621927532 3.38537014439072e-13 -56.0079323401788 54.8869873186428 -1.02042278281787 0.308444826170008 FOXRED1 other 3.48205613417959e-13 1 4.8217826966557e-09 7.65925621927532 -1.02042278281787 5.80278212275546e-61 1009.78501162622 46.6918376195818 21.6265853542404 7.09168658173388e-60 -103.973310242063 201.537524276141 -0.515900503469528 0.606365730219546 PPP6R3 other 9.25137553830904e-57 1 1.13062759172583e-55 21.6265853542404 -0.515900503469528 0.82709064864396 8.56094476692506 27.3863855836097 0.312598562551776 0.7548260802327 37.9135276056005 62.9588957469548 0.60219492663885 0.547547902112059 NRXN2 other 1 1 1 0.312598562551776 0.60219492663885 0.20407137553777 -51.9986410769633 105.776629653606 -0.491589127458938 0.623404835135568 -444.712042200251 249.560198575794 -1.78198304352282 0.0758634285956559 MS4A6A other 1 1 1 -0.491589127458938 -1.78198304352282 0.414461034822991 -28.8701190898562 47.5679450866156 -0.606923823118428 0.544405883768882 -148.239126942155 112.227680731871 -1.32087846755312 0.187648014357879 MS4A4A other 1 1 1 -0.606923823118428 -1.32087846755312 0.0707324631838555 2.67385155895284 67.5275666440888 0.0395964447089536 0.968443909280035 -243.71906360606 122.236423716012 -1.9938333943104 0.0471686754440624 ST3GAL4 other 1 1 1 0.0395964447089536 -1.9938333943104 8.96307748661749e-17 678.221799729722 74.3811376768004 9.118196103382 2.26766314205046e-17 163.002332633349 321.055164209222 0.507708178545682 0.612093447475267 CPT1A other 1.23860767787567e-12 1 3.40693710461662e-13 9.118196103382 0.507708178545682 9.94478261206938e-06 1202.14111703423 275.787547108327 4.35893908060337 1.95813589404262e-05 -848.076404076828 928.665555162024 -0.913220480034779 0.362066540862387 CCND1 og 0.0814875487232965 1 0.196229069150315 4.35893908060337 -0.913220480034779 2.42475961319209e-06 241.773010358653 58.4742256523366 4.13469366479746 4.73447401099639e-05 -182.069941252681 123.907688889237 -1.4693998644058 0.142875784051773 CCDC86 essential 0.0208990031061027 1 0.458013015823791 4.13469366479746 -1.4693998644058 3.11190854667856e-10 907.233512857713 161.649912675017 5.61233531057715 4.91535972579829e-08 -618.816618711525 344.780064092403 -1.79481554520994 0.0737932987644906 PRPF19 essential 3.45546325023187e-06 1 0.000591072007027244 5.61233531057715 -1.79481554520994 0.000142947437069938 -180.569955077917 171.995375357412 -1.04985354811248 0.294717336813591 -1559.98729393634 366.845707232418 -4.25243437003883 2.91035472436972e-05 TMEM109 other 1 0.442490332293172 1 -1.04985354811248 -4.25243437003883 0.0758833071886423 28.2662379670841 16.6513331119864 1.69753603372073 0.0907349466078978 -3.96619757609035 25.2741881779168 -0.156926804064702 0.875418527296478 CCKBR other 1 1 1 1.69753603372073 -0.156926804064702 0.126555160747662 -0.0244410516509877 2.77226425123203 -0.0088162777556742 0.992972158239994 -6.79177598862306 4.20787500275955 -1.61406315163092 0.107668937509156 HPX other 1 1 1 -0.0088162777556742 -1.61406315163092 6.9378156068747e-09 24.0999378946275 15.0051636109771 1.60610963795137 0.109405854663991 -87.7091263394289 22.7755535363874 -3.85102062170741 0.000146610221828159 TRIM3 other 7.136930914792e-05 1 1 1.60610963795137 -3.85102062170741 2.48846318996037e-13 307.032581000911 43.6792331068451 7.0292575936457 1.74594158462715e-11 -8.27363390906328 88.2503044262486 -0.0937519021928997 0.925376816966998 CHORDC1 essential 3.1329751561601e-09 1 2.38652755202685e-07 7.0292575936457 -0.0937519021928997 0.261690254406078 16.9087589773773 118.272309490405 0.142964647010204 0.886426745197036 -449.084527093497 304.116921228444 -1.4766837875363 0.140947755732313 FOLR1 other 1 1 1 0.142964647010204 -1.4766837875363 1.41979958528114e-10 121.488828953327 22.7608641698979 5.33761934724783 2.02433917280619e-07 -138.911306660154 58.5256512337716 -2.37351150703637 0.0183332525600873 ANAPC15 essential 1.60210185203124e-06 1 0.00235106751529711 5.33761934724783 -2.37351150703637 0.848971943939402 2.21470048610001 6.76808821622758 0.327226894116112 0.743754617608718 -5.60349970761189 17.4029758934285 -0.321985144490593 0.747717797615863 FOLR3 other 1 1 1 0.327226894116112 -0.321985144490593 3.56908862284633e-11 156.873205286101 36.2773870063704 4.32426969612099 2.15787086514279e-05 -178.761639307071 64.9121148121307 -2.75390256232514 0.00629036605716632 PANX1 other 4.13907207591489e-07 1 0.215463405884508 4.32426969612099 -2.75390256232514 0.0266261205053889 121.158734223596 60.502094198527 2.002554388052 0.0462476991746912 -144.019531519321 144.527162564404 -0.996487642626651 0.319925735744814 ARHGEF17 other 1 1 1 2.002554388052 -0.996487642626651 0.293608620106089 -2.5253056721397 1.92402300212237 -1.31251324404857 0.190449387648818 -4.75791773900931 3.33804319580817 -1.42536134492932 0.155195085217502 APOC3 other 1 1 1 -1.31251324404857 -1.42536134492932 1.91720366650498e-07 124.66065064883 35.5848300865569 3.503196456063 0.000536980953106553 -130.180882219916 63.7118053723801 -2.04327724601492 0.0419850269685502 CEP164 other 0.00180293832798128 1 1 3.503196456063 -2.04327724601492 1.08944044467825e-07 109.254905293282 71.4272759978021 1.5295964149136 0.127283052150133 -402.967028271193 111.191710131609 -3.62407438283153 0.000346244379507694 RNF141 other 0.00104128717702347 1 1 1.5295964149136 -3.62407438283153 0.2148571960927 25.8369834275483 14.7327548656626 1.75371026417918 0.08061902602803 20.1333169481409 26.0713005663719 0.772240605983034 0.440649861700371 CEP126 other 1 1 1 1.75371026417918 0.772240605983034 5.75264786641367e-13 4002.76907182331 1032.35751448066 3.87730899003235 0.00013314606119036 -5398.39354184738 1609.78684039636 -3.3534834590387 0.000914068836288207 EIF4G2 essential 7.15456815145868e-09 1 1 3.87730899003235 -3.3534834590387 0.124396548428016 -135.995684635874 66.3751721238867 -2.04889389035471 0.0414284352472799 -130.922403045172 118.674936702244 -1.1032017937676 0.270911055136756 IL10RA other 1 1 1 -2.04889389035471 -1.1032017937676 0.000386262616608136 162.320260390741 77.3208312144239 2.09930826972875 0.0367250925934892 -194.805990335068 122.725922778131 -1.58732552931988 0.113618026544842 GALNT18 other 1 1 1 2.09930826972875 -1.58732552931988 1.01979369405523e-11 397.639223898927 59.7767919611081 6.65206697873045 1.59128459165089e-10 -109.370929173878 130.74307253203 -0.836533263719069 0.403591995554566 BIRC2 other 1.20927136241069e-07 1 2.11513547922237e-06 6.65206697873045 -0.836533263719069 1.07596617061064e-18 303.093635033031 49.9904728910771 6.06302796321678 4.50354560481767e-09 -314.217770161191 88.6298857154944 -3.54528010077598 0.000462404423325693 UBE4A other 1.54185952248504e-14 1 5.67401710750979e-05 6.06302796321678 -3.54528010077598 5.20050106620413e-09 493.093377962039 123.686005721697 3.98665455388331 8.61557794641743e-05 -495.409347939091 221.71517647114 -2.2344404015283 0.0262666079334582 DDX6 essential 5.38979930501396e-05 1 0.812965935023948 3.98665455388331 -2.2344404015283 0.529053243976312 -33.55940120219 69.5045494986223 -0.482837475305917 0.629600949059506 -140.14437264243 124.684803355703 -1.12398920213735 0.26201224521323 UPK2 other 1 1 1 -0.482837475305917 -1.12398920213735 2.56775024111689e-08 253.763864453454 56.4361261364367 4.49647914954277 1.02517962997361e-05 -122.216720758524 101.433254348146 -1.20489795525088 0.229293839099056 CBL other 0.000255234373967019 1 0.105193681831592 4.49647914954277 -1.20489795525088 5.57648589469773e-09 2814.19138817351 873.628501700499 3.22126783031431 0.00143140618500435 -5038.00802485597 1581.06372549481 -3.18646740394938 0.00160814655382107 NECTIN1 other 5.76998995524374e-05 1 1 3.22126783031431 -3.18646740394938 2.99449547156981e-06 222.42886511372 86.8771203041412 2.56026977338839 0.0110098955904626 -572.348668799677 198.872242296486 -2.87797161730796 0.00432605089762099 HIPK3 other 0.0256149142638081 1 1 2.56026977338839 -2.87797161730796 0.70928163533126 24.9668256060224 85.641303597539 0.291527855803678 0.770873159261456 -110.932828218881 195.958623521183 -0.566103324393321 0.571797253843648 KIAA1549L other 1 1 1 0.291527855803678 -0.566103324393321 7.88142133485516e-19 219.650143736044 30.2857789133732 7.25258360910289 4.39612310062718e-12 -194.063423709109 69.2978656189212 -2.80042425514649 0.00547502359884358 FBXO3 other 1.13240261739199e-14 1 6.10006041443028e-08 7.25258360910289 -2.80042425514649 3.41604961265393e-27 304.951220712073 30.5353286735181 9.98683275928004 3.58653785524201e-20 -166.386473613037 70.4223988727359 -2.36269249949469 0.0188573955344196 PDHX other 5.29146085000093e-23 1 5.49421734044523e-16 9.98683275928004 -2.36269249949469 0.429722943425418 4.00216741553018 5.88676397098568 0.679858651587835 0.497182980771587 -9.63139090675164 13.5711294203725 -0.709697078880797 0.478511319031489 SLC1A2 other 1 1 1 0.679858651587835 -0.709697078880797 5.93679843289775e-13 173.520221619357 29.5492688952971 5.87223400464481 1.28817899007507e-08 -142.768736406839 65.5658754095723 -2.17748539945515 0.0303300173527273 COMMD9 other 7.38003413193519e-09 1 0.000159193159593477 5.87223400464481 -2.17748539945515 0.122478984951644 -86.006840780726 88.535028616704 -0.971444208292705 0.332190190511125 -384.89109673823 188.83470046939 -2.03824347845761 0.0424928019979498 SLC15A3 other 1 1 1 -0.971444208292705 -2.03824347845761 0.0939795927004818 -36.8595180713017 19.1126333266839 -1.92854210308323 0.0548283316826537 -66.5680676126537 40.7649768212161 -1.6329720461906 0.103631891533725 CD5 other 1 1 1 -1.92854210308323 -1.6329720461906 0.0473799234822984 12.1800327443429 21.1206233787461 0.576689074272295 0.56464089326426 -82.6760468286952 43.5704897116131 -1.89752392906108 0.0588498407693337 ACCS other 1 1 1 0.576689074272295 -1.89752392906108 0.000673248321201671 1447.66830557648 485.967666503772 2.97893955783423 0.00315962752359774 -886.776894757947 1046.62793031794 -0.847270428268207 0.397606075410277 MDK other 1 1 1 2.97893955783423 -0.847270428268207 4.22572557705528e-16 156.357917775344 28.8545898811201 5.41882308566966 1.34437767955357e-07 -244.344165813349 62.1440926404006 -3.93189690977156 0.000107559660547284 AMBRA1 other 5.74614163967978e-12 1 0.00157843383356385 5.41882308566966 -3.93189690977156 2.95248150354339e-09 138.649519315076 46.5325300586424 2.9796256326562 0.00314874893608038 -375.950253827388 98.9858487659448 -3.79802020707358 0.00018021058614127 MADD other 3.10719153432906e-05 1 1 2.9796256326562 -3.79802020707358 5.47822610844594e-15 215.01975696085 36.6791222811311 5.86218381434561 1.32900252119182e-08 -239.444644550045 78.5295180373911 -3.04910370691484 0.00252320851199347 PTPMT1 essential 7.240571447533e-11 1 0.000164118521341977 5.86218381434561 -3.04910370691484 3.33462496935247e-05 110.877297671523 45.6392859616882 2.42942665151683 0.0157704799657123 -287.146450756468 97.4933921528073 -2.94529141325195 0.00350562039830904 NAA40 other 0.260000708860412 1 1 2.42942665151683 -2.94529141325195 2.93153412984526e-14 195.794093651109 71.2561634250684 2.74774958740239 0.00640173630350094 -443.125964200948 104.475740852445 -4.24142447409672 3.04751986380599e-05 CARS other 3.79897507886647e-10 0.463040168106682 1 2.74774958740239 -4.24142447409672 0.000315834601872077 31.7269712690515 52.642094392543 0.602692040184969 0.547215721812961 -197.263231216499 76.2280881466464 -2.58780242313053 0.010177924258753 SLC22A18 other 1 1 1 0.602692040184969 -2.58780242313053 2.93260056181002e-06 293.429455770812 602.908225171255 0.486690085688355 0.626868465827037 -3101.08119982826 886.648822544193 -3.49753038743103 0.000548013296352875 CD81 other 0.025100128208532 1 1 0.486690085688355 -3.49753038743103 1.65678865762257e-07 286.561794429656 62.1036075915266 4.61425359239122 6.11168360049391e-06 -78.09336547637 109.339993941415 -0.714225075942596 0.475707299941022 SLC35F2 other 0.0015631800984669 1 0.0638304235235584 4.61425359239122 -0.714225075942596 0.0808510904205548 -10.7988550760463 6.72248445941362 -1.6063785853643 0.109346759260798 -22.2347816187663 9.88621929783368 -2.24906821798283 0.0253054693330298 C11orf21 other 1 1 1 -1.6063785853643 -2.24906821798283 0.470588024311607 426.603671543139 429.490857913383 0.993277653488898 0.321477347580582 -11.3621843873585 717.059186124621 -0.0158455321502343 0.987369501894714 CALCA other 1 1 1 0.993277653488898 -0.0158455321502343 9.36449727263055e-26 903.857777900562 107.095395571829 8.43974452005589 1.93816015638147e-15 -478.249786826625 201.86300256483 -2.36917999212378 0.018528772207378 C11orf58 other 1.44128977523057e-21 1 2.85142122206842e-11 8.43974452005589 -2.36917999212378 5.45343796388499e-06 228.001328903655 52.9247367645863 4.30802953102676 2.31706719322799e-05 -182.892580287929 153.977249799508 -1.18778962818255 0.235971851337518 PITPNM1 other 0.045661636071609 1 0.230907360009686 4.30802953102676 -1.18778962818255 1.16461280929069e-16 2081.1404179051 292.979529365974 7.10336460164579 1.06641545101263e-11 -521.882323472586 552.871652305487 -0.943948421475987 0.346033708413269 RPS13 essential 1.60402122223606e-12 1 1.46600132050707e-07 7.10336460164579 -0.943948421475987 2.80482550405338e-12 231.206668617562 35.9550008493433 6.43044536659453 5.84063456766694e-10 -214.309830788563 104.606134782429 -2.04873099684171 0.0414660199119378 AIP other 3.39692416795905e-08 1 7.60801058784296e-06 6.43044536659453 -2.04873099684171 3.76768943298177e-23 619.304600938968 125.776668498886 4.92384325590921 1.4826138353356e-06 -893.773524808983 186.194710389514 -4.80020900131499 2.63251751437447e-06 NUP98 essential 5.69599288478184e-19 0.0409646050411811 0.0162420345661015 4.92384325590921 -4.80020900131499 0.307607394744034 -56.5457538831566 61.7939634705697 -0.915069218858042 0.36098406101944 -366.323648977825 258.780784200911 -1.41557515604953 0.158069680320043 TCIRG1 other 1 1 1 -0.915069218858042 -1.41557515604953 2.64180121508095e-48 908.561208824882 49.4889334318583 18.3588763349666 3.44014047473351e-49 523.332250909433 207.249774629886 2.52512820264349 0.0121473128704624 CHKA other 4.20521917416586e-44 1 5.47773567791816e-45 18.3588763349666 2.52512820264349 0.0272009358163669 38.8112322055369 29.6549892977937 1.30875893482195 0.19173301290505 -73.7021997890614 52.2107567644088 -1.41162864429697 0.159214964408504 EXPH5 other 1 1 1 1.30875893482195 -1.41162864429697 4.58670692292745e-08 105.765161462128 38.9922559455397 2.71246581910648 0.00710425705796958 -220.620196296721 74.4172744484755 -2.96463687943144 0.00329907398115441 HPS5 other 0.000448809272408451 1 1 2.71246581910648 -2.96463687943144 3.83728896900162e-24 271.954428388435 35.9714497422065 7.56028545797924 6.18818715020579e-13 -209.925940172364 68.6520228917798 -3.05782599448354 0.00245163663241739 GTF2H1 essential 5.84610974427397e-20 1 8.75628481754119e-09 7.56028545797924 -3.05782599448354 0.520311894705066 20.5781724605302 125.909961909995 0.163435618185956 0.870297275545887 -202.82092554446 226.329445207369 -0.896131413032138 0.370977898514929 POU2AF1 og 1 1 1 0.163435618185956 -0.896131413032138 0.651944992009078 -337.695003113541 444.655141249124 -0.759453724441122 0.448243733055817 -1356.53865680883 2032.91827882983 -0.667286369026931 0.505159124545373 VWF other 1 1 1 -0.759453724441122 -0.667286369026931 8.26639008511555e-10 212.069151241954 36.1754167162045 5.86224487490033 1.3189563158844e-08 -101.952262527907 75.5510909188725 -1.34944792044611 0.178315255296782 PSMD9 other 8.97729963243549e-06 1 0.000162917484138041 5.86224487490033 -1.34944792044611 0.0311640653288288 117.629285898246 44.378095104654 2.65061593159527 0.00850537796823757 102.617813912185 209.869176928141 0.488960863211088 0.625263430090673 P3H3 other 1 1 1 2.65061593159527 0.488960863211088 1.76936687139788e-05 221.99158086658 46.5322552809929 4.77070323641196 3.00364493623267e-06 309.703614328614 291.940138628603 1.06084629466662 0.289704278699227 PPFIBP1 other 0.141938610423538 1 0.0321690372670519 4.77070323641196 1.06084629466662 0.00115845199409646 60.1904619524595 40.4961581240826 1.48632524023717 0.138347046858196 -280.167850201824 103.9912820649 -2.69414747696805 0.00749415955575414 PRPF40B other 1 1 1 1.48632524023717 -2.69414747696805 0.108077393938289 -20.8102934161297 19.8634465989279 -1.04766780087666 0.295728618099003 145.504594963409 90.1074659798731 1.61478955579451 0.10752423199428 CD69 other 1 1 1 -1.04766780087666 1.61478955579451 3.64915290672737e-08 149.994182142168 31.9701503045976 4.69169461867053 4.30296657817258e-06 -157.717471525741 71.0834554258738 -2.21876483889011 0.0273313349374648 PRDM4 other 0.000359040154492906 1 0.0455296893636441 4.69169461867053 -2.21876483889011 0.145145444850926 107.622903012946 55.1107496322803 1.95284774261005 0.0518706933740536 23.6200624296709 250.001427138231 0.0944797103762567 0.924798175671702 CLEC2B other 1 1 1 1.95284774261005 0.0944797103762567 2.59979418535261e-06 129.674791640704 28.5668376741976 4.53934709608513 8.49329427318117e-06 -57.0998325241419 59.6084128922582 -0.95791566581968 0.338959079176194 COQ5 other 0.0223454275066303 1 0.0877102499591419 4.53934709608513 -0.95791566581968 0.681604139371562 -48.3570768512124 71.1509950978746 -0.679640204394794 0.497312415951974 49.702724521711 153.073201444289 0.324699059356907 0.745659348347237 SELPLG other 1 1 1 -0.679640204394794 0.324699059356907 0.0147428725262211 606.019654535116 261.457932081476 2.31784765415442 0.0212025213819469 -569.923336650556 562.4967388251 -1.0132029171244 0.311866995581793 CORO1C other 1 1 1 2.31784765415442 -1.0132029171244 0.00154241012636452 70.0818179525336 20.5264868604438 3.41421395823886 0.000736801601494267 -0.695492004842502 52.3999747456051 -0.0132727545808757 0.989419879279083 ASIC1 other 1 1 1 3.41421395823886 -0.0132727545808757 5.89893641162772e-08 164.323678876589 27.6386159643091 5.94543804540671 8.46620273752485e-09 162.063179308639 180.21476141417 0.899278050459944 0.369302925848976 CAPRIN2 other 0.0005729636936614 1 0.000105471953704085 5.94543804540671 0.899278050459944 0.518926052731977 -0.911872848671523 20.6479323940513 -0.044162913325609 0.964807067001036 150.111401619575 134.632725998112 1.11496963688962 0.265851213293816 TSPAN11 other 1 1 1 -0.044162913325609 1.11496963688962 0.00659487771034 128.819006661522 61.2489078952914 2.1032049564336 0.0363698152884435 -220.268100857062 131.769997082988 -1.67161042523464 0.0957554005830692 KCTD10 essential 1 1 1 2.1032049564336 -1.67161042523464 4.20431016280059e-07 219.064263700498 57.3098766950397 3.82245219033002 0.000163705882141312 -354.165235554021 145.920646637513 -2.4271084573372 0.0158670086498239 SLC11A2 other 0.00386418147063002 1 1 3.82245219033002 -2.4271084573372 0.000100020773576071 701.30087001376 200.568786143012 3.49656037462235 0.00055022644604446 -576.213391372179 418.516054555413 -1.37680116473497 0.169705875933774 MLEC other 0.741554015292992 1 1 3.49656037462235 -1.37680116473497 0.0103857228056998 45.2138287501528 32.1918914536364 1.40450985352231 0.161312169892532 -149.735895040416 69.2571604736752 -2.16202763752249 0.0314913136695415 MVK essential 1 1 1 1.40450985352231 -2.16202763752249 2.30599430840904e-05 67.7779584808186 27.3462333290011 2.47851167162167 0.0138000582869288 -195.439538493043 68.3816755052947 -2.85806887662339 0.00459185521528701 CSRNP2 other 0.182957588429173 1 1 2.47851167162167 -2.85806887662339 1.32001696125197e-07 209.934775180112 56.0739715328021 3.74388989118248 0.000221121900289408 -343.681165817126 116.089659435055 -2.96048043804793 0.00334248734863942 CAMKK2 other 0.00125421043586499 1 1 3.74388989118248 -2.96048043804793 0.365444067431044 -18.281354635033 26.3083805716579 -0.694887113451884 0.487719210461203 59.849036972264 65.7864328764075 0.9097474107572 0.363761168592323 BIN2 other 1 1 1 -0.694887113451884 0.9097474107572 0.200547503275582 1.84041527644676 16.1257705749425 0.114128826767915 0.909219867961226 -71.0117774224462 42.9281126194915 -1.65420217869544 0.0992399323232818 IL23A other 1 1 1 0.114128826767915 -1.65420217869544 1.44923521018623e-11 4221.6065376754 616.931788731642 6.8429064846126 5.13104524399003e-11 -640.067410678612 1651.23927648574 -0.387628504114097 0.698594128627071 ATP5B essential 1.70951785393568e-07 1 6.92024072056936e-07 6.8429064846126 -0.387628504114097 6.76766368636907e-06 1150.64624273496 297.575617100364 3.86673563495249 0.000138050969112912 -1343.58160818481 796.471434371724 -1.68691750915669 0.0927656771951575 PTGES3 other 0.0561716085968633 1 1 3.86673563495249 -1.68691750915669 2.55318619010925e-07 151.868811217548 50.5417482529917 3.00481911423708 0.00290523199782072 -386.369946302704 105.554671212677 -3.66037752629845 0.000302492192262769 BCL7A other 0.00238084612227688 1 1 3.00481911423708 -3.66037752629845 8.45872928017026e-05 125.141554247663 54.2684692908576 2.30597169743177 0.0218644512653526 -331.334619594717 112.466556981881 -2.94607240131035 0.00349705790632908 RSRC2 essential 0.632543775571132 1 1 2.30597169743177 -2.94607240131035 0.491449246183859 8.9185417568152 11.7449139233621 0.759353522299988 0.448296280384388 -18.6718411942882 30.6412907386495 -0.609368624629654 0.542786923710332 CYP27B1 other 1 1 1 0.759353522299988 -0.609368624629654 0.0310789134988522 112.574501851525 45.3153862191548 2.48424456336068 0.0136055962898819 167.156238108938 101.833432377007 1.64146719016692 0.101895710971638 LIN7A other 1 1 1 2.48424456336068 1.64146719016692 0.000119124603037864 2085.84323684943 582.104449407573 3.5832800092359 0.000401709779856175 -1572.48058725299 1525.87232333518 -1.03054532361917 0.303666217764986 KRT18 other 0.873540714076657 1 1 3.5832800092359 -1.03054532361917 0.934480254183762 9.45443705664803 31.751355598045 0.297764831723599 0.76611596499139 -8.72729936743399 69.8578879051264 -0.1249293333816 0.900674212467221 ACSS3 other 1 1 1 0.297764831723599 -0.1249293333816 0.749588951096019 -31.3539250629102 117.492722262755 -0.266858444157858 0.789779618524113 -240.240274655896 316.276236760928 -0.759590025214233 0.448155090781748 TNS2 other 1 1 1 -0.266858444157858 -0.759590025214233 0.073626948433207 38.3966974060784 20.9379581888124 1.83383198398947 0.0677674352425903 -38.7519193204016 56.0756026079984 -0.691065588564433 0.490111519456227 GLI1 og 1 1 1 1.83383198398947 -0.691065588564433 0.000749083409656709 164.257286132383 63.2168178249431 2.59831626747231 0.00988274484180006 -331.307942343188 179.145817371157 -1.84937581688987 0.0654964258668851 PPM1H other 1 1 1 2.59831626747231 -1.84937581688987 2.34009964630905e-17 551.600389048465 68.3269563932558 8.07295419210143 2.22962266838436e-14 -358.227366105517 157.465793640612 -2.27495354910609 0.0236871942636535 METAP2 essential 3.27754356462046e-13 1 3.2316150955563e-10 8.07295419210143 -2.27495354910609 0.32352873244774 187.747936965599 189.589510147406 0.990286523867409 0.322914202422326 -343.109582602722 430.047287034852 -0.79784152335535 0.425658440681716 LTA4H other 1 1 1 0.990286523867409 -0.79784152335535 0.00347387673197941 -95.2995873931196 75.9190270775913 -1.25527935567089 0.210454723377668 -583.555356206726 172.207690202159 -3.38867187360608 0.000806274598990151 ELK3 other 1 1 1 -1.25527935567089 -3.38867187360608 0.708929251513195 -2.79253733052213 3.86472010255062 -0.722571688614428 0.470587545744103 4.42168564339025 17.3647903423391 0.254635129835644 0.799204671893826 SLC6A12 other 1 1 1 -0.722571688614428 0.254635129835644 0.0255604735025635 51.9302792654934 24.6449271884751 2.10713867678936 0.0360244620339576 -152.909751963836 116.466328118653 -1.31290952873568 0.190324112710605 WNT5B other 1 1 1 2.10713867678936 -1.31290952873568 4.67137003187064e-20 152.5412605813 14.8886786725161 10.2454532021626 4.8041736512085e-21 92.2330655910817 66.5775629915348 1.38534757727328 0.167081206397008 MAGOHB other 6.83374721962357e-16 1 7.38833865819355e-17 10.2454532021626 1.38534757727328 0.0217389377631522 74.1198811223907 65.7675359094022 1.12699799524942 0.260740231384642 -294.542249797366 140.541115265882 -2.09577282235265 0.0370300529055017 TRPV4 other 1 1 1 1.12699799524942 -2.09577282235265 1.53312896351854e-26 1346.12787098132 112.835172015249 11.9300378325243 1.18381426985203e-26 -216.824003072744 533.059657776348 -0.406753728048419 0.684509929086074 FOXM1 other 2.36669118098357e-22 1 1.85645753798196e-22 11.9300378325243 -0.406753728048419 0.922631759276475 23.0620297315387 81.7643958749501 0.282054670431487 0.778116077417723 -82.3757934848789 363.719985471197 -0.226481350421703 0.820997169270009 PRR4 other 1 1 1 0.282054670431487 -0.226481350421703 0.0866047002247242 7.77666842549926 3.50902639059548 2.21618978025969 0.0275061930518269 9.23929526731718 16.5336160079235 0.558818788514828 0.576745163290322 PRMT8 other 1 1 1 2.21618978025969 0.558818788514828 2.16168973549982e-15 90.3842497157159 11.0610322908286 8.17141179405643 1.16046934162263e-14 -80.621137070775 51.1010420332755 -1.57768088208998 0.115801201397628 PARP11 other 2.88758514868067e-11 1 1.68975940833671e-10 8.17141179405643 -1.57768088208998 0.0084116626951786 425.424434237782 161.351228077146 2.6366358614536 0.00885642909092074 -276.576102255328 344.797493625421 -0.802140698144961 0.423174412809032 ARPC3 essential 1 1 1 2.6366358614536 -0.802140698144961 8.02016778260545e-07 141.243274537806 27.4441380937146 5.14657352530061 5.10115358753264e-07 -8.23166467250752 58.6464084729394 -0.140360934059684 0.888479089578545 GPN3 essential 0.00719489251777535 1 0.00576277320783562 5.14657352530061 -0.140360934059684 0.000779878253633171 229.27287815045 74.8780013951109 3.06195242766483 0.00242004797551455 -205.922056042301 160.009610812326 -1.28693554716426 0.199214912013425 VPS29 essential 1 1 1 3.06195242766483 -1.28693554716426 4.56327265613888e-24 217.123909008399 19.0325874868384 11.4080079315829 6.78668464365288e-25 72.8856708974198 87.8167312031297 0.829974765615304 0.407280896102533 RAD51AP1 other 6.9494079280339e-20 1 1.0604873424172e-20 11.4080079315829 0.829974765615304 0.488247000899482 42.924395460757 67.8114591903793 0.632996192284369 0.527267946800781 -109.98501412437 141.304960152736 -0.778352111670304 0.437038017528028 SH2B3 other 1 1 1 0.632996192284369 -0.778352111670304 0.00128372947652323 7.06312803647757 1.96726831174564 3.59032267957906 0.000392207322609148 -1.53860889505399 8.9404856753759 -0.17209455402313 0.863492114514439 AKAP3 other 1 1 1 3.59032267957906 -0.17209455402313 0.00322161687739764 126.066384076476 52.9776689562572 2.37961364779124 0.0180231224177322 -441.837096327139 236.41800848661 -1.86888088244835 0.0627180563345523 MANSC1 other 1 1 1 2.37961364779124 -1.86888088244835 0.766732653812197 -3.64371395380043 11.9088275974079 -0.305967478662092 0.759865189480191 -37.6354938185792 52.9804569631484 -0.710365594708956 0.478090563991063 KCNA1 other 1 1 1 -0.305967478662092 -0.710365594708956 2.36924459880875e-07 292.10055610799 53.836638428598 5.42568341252203 1.27717714271805e-07 -82.5673746548713 232.960506812606 -0.35442648964225 0.723293903660986 DUSP16 other 0.00221358522866702 1 0.00150144944897934 5.42568341252203 -0.35442648964225 0.000687185276093829 135.696943657243 35.2853245816034 3.84570484376361 0.000149774065946463 77.3688613829329 152.685742228867 0.506719620663478 0.612762075483286 CREBL2 other 1 1 1 3.84570484376361 0.506719620663478 2.05473110594894e-05 72.3978931699775 26.4403791631197 2.73815639039555 0.00659085550314519 -159.861963512147 55.0394052616185 -2.90450019858092 0.00398386359778732 ACAD10 other 0.163762069144131 1 1 2.73815639039555 -2.90450019858092 0.98559336201734 -64.4365374706596 398.873443304662 -0.161546321401605 0.871784397465488 -82.0522222858347 830.311734892388 -0.0988209835387537 0.921354006740873 ALDH2 other 1 1 1 -0.161546321401605 -0.0988209835387537 2.76102375962515e-07 481.612069974671 85.5151517394571 5.63189166104763 4.44125805255075e-08 322.289468166258 370.038948769105 0.870960933270184 0.384543531503572 CDKN1B ts 0.00256885650595524 1 0.000534816294688162 5.63189166104763 0.870960933270184 0.250017941407352 5.76027736113243 10.1926363410659 0.565141065410567 0.572443643178704 -60.8003829200345 43.6639902483305 -1.3924605280975 0.164920247430503 GPRC5D other 1 1 1 0.565141065410567 -1.3924605280975 6.71921127812781e-08 145.094046671943 34.1747484412928 4.24565075939603 3.0009120640243e-05 -195.524673432605 72.2794204816803 -2.70512231738441 0.0072621793907989 NAA25 essential 0.000650554035948334 1 0.296198180890155 4.24565075939603 -2.70512231738441 0.0311602941501981 499.390833154305 211.565190286491 2.36045841226553 0.0189636259010971 -712.620409972919 981.840732187366 -0.725800414070547 0.468589781111587 SCNN1A other 1 1 1 2.36045841226553 -0.725800414070547 5.77969882791491e-12 1109.37276805666 155.199593996306 7.14803911202928 8.23376465845705e-12 -758.608561298368 733.928106721557 -1.03362789127542 0.30223507477458 LTBR other 6.91078588853785e-08 1 1.13543614640123e-07 7.14803911202928 -1.03362789127542 7.16838301501077e-08 64.6760251769343 15.6172575451111 4.1413177051166 4.61235273059408e-05 -92.7299589517048 32.3920834461319 -2.86273524535447 0.00452675121445878 OGFOD2 other 0.000692967586061091 1 0.446752485485342 4.1413177051166 -2.86273524535447 0.000369117175455343 511.476270191399 163.98650690328 3.11901436191375 0.00200952036353957 -561.815496777238 341.547059646117 -1.64491387324296 0.101142708718199 CDK2AP1 other 1 1 1 3.11901436191375 -1.64491387324296 0.0879055232674683 342.431511738578 231.817263448592 1.47716139274725 0.140793520708895 -580.8671875 489.699802850344 -1.18616994354298 0.236594099405389 OAS3 other 1 1 1 1.47716139274725 -1.18616994354298 0.133602464374603 255.013107093693 193.932355675853 1.3149590546919 0.189635278111371 -454.61281779661 409.670250299666 -1.10970424985478 0.268110218826109 OAS2 other 1 1 1 1.3149590546919 -1.10970424985478 0.791053272314411 -2.18374526939245 4.03015306403687 -0.541851695132657 0.588365899719044 -9.1442623479952 17.088989562809 -0.535096724963541 0.593021770366388 ART4 other 1 1 1 -0.541851695132657 -0.535096724963541 0.338555258949996 -353.096411329423 256.889023627641 -1.3745095307818 0.170419082654091 188.223794744948 1072.90381131932 0.175433988358653 0.860869644632357 MGP other 1 1 1 -1.3745095307818 0.175433988358653 0.265691069667065 81.0464790985547 65.5530153626939 1.23635013050335 0.217398909512807 -95.3584480932202 138.476739056475 -0.688624304290773 0.491648807144095 RASAL1 other 1 1 1 1.23635013050335 -0.688624304290773 0.369228002085764 -196.34794930969 146.087448033213 -1.34404394048317 0.180062440717579 56.3982595612455 609.107863467386 0.0925915801516577 0.926296697279043 ARHGDIB other 1 1 1 -1.34404394048317 0.0925915801516577 7.65018927206061e-09 218.505298400409 40.4362544480362 5.40369778019885 1.42695391479614e-07 -147.639482785726 84.2196353263058 -1.753029233785 0.0807235310076949 GTF2H3 essential 7.84985921206139e-05 1 0.00167210459735812 5.40369778019885 -1.753029233785 2.86862153420766e-10 251.685300316381 40.7154136589199 6.18157296459745 2.31304650023223e-09 -113.465040874077 84.8010612585424 -1.33801439734514 0.182009263392464 EIF2B1 essential 3.19134145680603e-06 1 2.94751515524593e-05 6.18157296459745 -1.33801439734514 2.99921353200607e-06 123.173300925562 30.8903643368716 3.98743438511467 8.58888320996085e-05 -135.848038830373 64.3376903983844 -2.11148454333985 0.0356428224971227 DDX55 essential 0.0256492741257159 1 0.810532908524005 3.98743438511467 -2.11148454333985 0.000319994141740402 706.445370810618 219.605910212848 3.21687777039294 0.00145821119040544 -758.214709318829 554.932097818637 -1.36631979353739 0.173005656893445 SLC38A1 other 1 1 1 3.21687777039294 -1.36631979353739 0.873159348693064 0.771574156780819 11.8200012578858 0.0652769944729114 0.948002675353035 -25.3428962152028 51.9730496035408 -0.487616108897259 0.626224935779384 RERGL other 1 1 1 0.0652769944729114 -0.487616108897259 0.812680915068605 2.08166997354497 6.11794690730716 0.340256299226569 0.733928092111854 -6.37035714285716 15.6751416094967 -0.406398698114325 0.684771604287155 ENDOU other 1 1 1 0.340256299226569 -0.406398698114325 0.079630669980939 165.291281958014 81.5234130743001 2.02753142593979 0.0435829991258629 -65.5883467547736 172.226993537152 -0.380825011269938 0.703630357880672 C12orf49 other 1 1 1 2.02753142593979 -0.380825011269938 0.0403006463957368 -159.141266255477 63.2666142570351 -2.51540671370416 0.0124704625678345 -68.9630115396424 161.121785184413 -0.42801792110676 0.668979281575907 VDR other 1 1 1 -2.51540671370416 -0.42801792110676 0.143484941564913 137.993334868068 72.4901902777753 1.90361391436954 0.0580197849126536 -9.02509838743256 151.087844099798 -0.0597341132319768 0.952411427222828 FZD10 other 1 1 1 1.90361391436954 -0.0597341132319768 7.62058787637091e-09 216.638473932801 38.7458488020703 5.59126927479327 5.49799096000417e-08 -90.034597420924 80.578211988554 -1.11735660545202 0.264831486797183 RFC5 essential 7.82177139630711e-05 1 0.0006593190759237 5.59126927479327 -1.11735660545202 0.959467801772521 -4.28327016039131 18.3019842070801 -0.234033103292392 0.815135332966184 -8.38096130400343 37.9909866929068 -0.220603938817104 0.825566329401607 STX2 other 1 1 1 -0.234033103292392 -0.220603938817104 0.931204708252489 21.4359159822558 58.1828980086129 0.368422968190457 0.712845504955435 0.938239119203273 122.717758769154 0.0076455040298463 0.993905454879422 ADGRD1 other 1 1 1 0.368422968190457 0.0076455040298463 3.72295235558658e-10 646.018564495593 127.076971340355 5.0836792668385 6.91208602969377e-07 -944.065967927698 348.600488995429 -2.70816019406122 0.00719619143795056 COPZ1 essential 4.11944678145655e-06 1 0.00774637481347781 5.0836792668385 -2.70816019406122 0.000167811802311633 82.7626197293204 21.2634120497929 3.89225489942601 0.000125197641967926 -29.2396932965951 63.3065602829263 -0.461874617194783 0.644543160934174 TBC1D30 other 1 1 1 3.89225489942601 -0.461874617194783 7.65123056266573e-17 787.949408642666 95.0671370880209 8.28834687546253 5.51082654235935e-15 -893.716527142198 396.920449990547 -2.25162630739606 0.0251529499230718 CAND1 other 1.05915984678982e-12 1 8.06068598350901e-11 8.28834687546253 -2.25162630739606 0.761378741340096 1.23684784602646 1.7110290615493 0.722867819034309 0.47038911548822 0.0260018740982771 7.14381905103805 0.00363977221602483 0.997098586108579 IFNG other 1 1 1 0.722867819034309 0.00363977221602483 2.13957192576114e-08 340.999662306474 118.57394173652 2.87583981195633 0.00434839050255385 -1313.48062303013 315.653475345348 -4.16114735183284 4.25149238650146e-05 RAB5B other 0.000213572069629477 0.643378342849266 1 2.87583981195633 -4.16114735183284 1.76173787821852e-14 64.7650841068832 8.39467385129272 7.71502088754881 2.34578576188118e-13 -61.4269184770846 35.4845197794616 -1.73109059552888 0.0845779850801485 MDM1 other 2.2944874125918e-10 1 3.34837459650919e-09 7.71502088754881 -1.73109059552888 2.54923903535326e-35 433.675976054351 30.5370336180869 14.2016405875614 1.44249164583114e-34 -106.633909518387 129.080890171835 -0.826101442099089 0.409475925848186 NUP107 essential 4.02907229537583e-31 1 2.28606076031318e-30 14.2016405875614 -0.826101442099089 5.07494253302886e-44 416.160464806338 25.8334865250576 16.1093418189092 2.69718167993025e-41 -245.275594450265 106.41419951139 -2.30491415221343 0.0219358166405296 CNOT2 other 8.06865113326259e-40 1 4.28609140757717e-37 16.1093418189092 -2.30491415221343 9.46498997697652e-12 583.671594490688 90.2899547205339 6.46441341450743 4.68797637225853e-10 -332.19016763453 240.359201852634 -1.38205720885277 0.168088049408087 TIMELESS essential 1.1232103605678e-07 1 6.12577872563023e-06 6.46441341450743 -1.38205720885277 9.73319276960884e-06 179.97190567314 42.6572319385488 4.21902447707821 3.35327793101501e-05 -280.889366810525 180.31330546897 -1.55778502357311 0.120455559887051 CPSF6 essential 0.0798511134818709 1 0.329224827267054 4.21902447707821 -1.55778502357311 1.96962623835295e-08 329.353135003566 64.3812580757006 5.11566789540376 5.9511246215829e-07 -253.147405525614 151.70549093133 -1.66867661790965 0.0963449330286742 KRR1 essential 0.000197041408884829 1 0.00669977609897803 5.11566789540376 -1.66867661790965 7.65478895018406e-22 716.923944735061 67.3472532957179 10.6451846163212 2.51231328704817e-22 40.9641349672188 318.480485879363 0.128623688996555 0.89775117704302 MRPL51 other 1.1436254691575e-17 1 3.8860461924061e-18 10.6451846163212 0.128623688996555 9.09087632110493e-14 35498.4959139629 4477.45555347647 7.92827432678823 5.89417979919681e-14 -11462.9735758227 21155.9826436752 -0.541831299868724 0.588381579501035 GAPDH essential 1.16081399744189e-09 1 8.48290356700405e-10 7.92827432678823 -0.541831299868724 3.7784808318397e-21 615.562051890113 59.8857979382641 10.2789321188421 3.93240550719618e-21 -170.22348518776 282.96046418615 -0.601580456398233 0.547958211813214 NOP2 essential 5.60386492170146e-17 1 6.05000587282132e-17 10.2789321188421 -0.601580456398233 1.32742811007782e-06 755.561066634821 157.062725670257 4.81056892022282 2.5054468713807e-06 -997.486424660669 742.121559569321 -1.34410112709776 0.180043973240152 CHD4 essential 0.0117118982152166 1 0.026996190039127 4.81056892022282 -1.34410112709776 0.000104161869234884 11.7459450615351 2.75913154049537 4.25711673732896 2.85382637774572e-05 22.4339974411299 13.0591938520762 1.7178700075398 0.0869583961556512 ACRBP other 0.770485346730435 1 0.282386120077939 4.25711673732896 1.7178700075398 6.54762689948544e-05 58.5427740558046 18.9141699373125 3.0951807163536 0.00217372563656649 -85.0661120518299 39.3165963467996 -2.16361841959787 0.0313708731713528 UHRF1BP1L other 0.495786308829037 1 1 3.0951807163536 -2.16361841959787 6.96212543804315e-21 540.592143201228 53.5629490021587 10.0926508579548 1.49680629097654e-20 -247.966105503537 253.517791392606 -0.978101395335719 0.328893300001466 COPS7A other 1.02921100350592e-16 1 2.2971486147617e-16 10.0926508579548 -0.978101395335719 1.91217030671562e-05 132.008674457504 28.9297368332822 4.56307899440118 7.63728906705019e-06 299.710205144987 136.926795932155 2.18883530505956 0.0294590494918884 ING4 other 0.152916259428048 1 0.07912231473464 4.56307899440118 2.18883530505956 0.00211794670432867 17.3987343731748 4.90236368638486 3.54905010852124 0.000455321142367761 16.7974223039109 23.1838484603207 0.724531232709694 0.469362419950953 GNB3 other 1 1 1 3.54905010852124 0.724531232709694 9.80085448726968e-21 245.69934783557 23.7060429292229 10.3644184130238 1.97326769060302e-21 58.1532586407566 112.108636164905 0.518722380631024 0.60437609946375 CDCA3 other 1.44611607959664e-16 1 3.04060818445019e-17 10.3644184130238 0.518722380631024 0.0498346474922717 87.0009056467164 57.1374243815382 1.52266061322196 0.129009641923376 -178.819628379011 125.718386712511 -1.42238246174707 0.156065228853606 CHPT1 other 1 1 1 1.52266061322196 -1.42238246174707 9.45480335744233e-27 885.90304437223 74.1333370499947 11.9501303951121 9.71267851619054e-27 -155.215427474502 350.585179308141 -0.442732427482561 0.658311159527495 USP5 essential 1.46133440692629e-22 1 1.52372500561997e-22 11.9501303951121 -0.442732427482561 1.24813370864266e-22 5119.55491114716 472.903339051422 10.8257956507904 6.01823799211751e-23 -215.904119585054 2236.41493171895 -0.0965402781580903 0.923162578323731 TPI1 essential 1.87806679139462e-18 1 9.33910171616795e-19 10.8257956507904 -0.0965402781580903 0.000114746835768183 234.868927142563 91.0022207976156 2.58091423576244 0.0103801402693402 -520.850600123583 200.230453328389 -2.60125566049316 0.00979864303940104 GNPTAB other 0.843733483403452 1 1 2.58091423576244 -2.60125566049316 0.00135157542018267 562.291533965605 156.244492427307 3.59879266929816 0.000379752599840078 -45.0104819177063 738.898390026555 -0.0609156583980224 0.951471113430842 ENO2 other 1 1 1 3.59879266929816 -0.0609156583980224 4.30209151864542e-19 1456.98698325783 148.655702309906 9.8010837163879 1.30930166640015e-19 -2.4049446172825 714.132089427022 -0.00336764676015622 0.997315489364294 ATN1 other 6.20834827055721e-15 1 2.0008748065927e-15 9.8010837163879 -0.00336764676015622 1.37722060727116e-06 335.828626820755 68.5823746464258 4.89671914325085 1.67683643885888e-06 969.458442717209 329.46515836988 2.94252189674281 0.0035371969380375 C12orf57 other 0.0121319363294516 1 0.0182942855479504 4.89671914325085 2.94252189674281 2.58339745769394e-06 228.975595678927 44.245478055316 5.17511858257379 4.43997420863916e-07 100.938613010044 212.552328638353 0.47488829530438 0.635249074096046 PTPN6 other 0.022224968328541 1 0.00504159071390977 5.17511858257379 0.47488829530438 4.34661212553524e-12 516.948184804391 70.7190979683443 7.30988091838772 3.01046347740648e-12 -246.157063707426 339.729834845108 -0.724567107330022 0.469342736658648 LPCAT3 other 5.22201980761803e-08 1 4.19688713385237e-08 7.30988091838772 -0.724567107330022 0.0037918455009686 80.5550079268363 38.1997209752386 2.1087852442444 0.0358740008798396 -154.607479625695 82.7900156257633 -1.86746527896032 0.062908150448827 NT5DC3 other 1 1 1 2.1087852442444 -1.86746527896032 0.00563398940783577 73.4384789467226 22.9134062563857 3.20504416170145 0.00151712806856852 17.0702166085106 104.606731018369 0.163184686514227 0.870498343898161 SLCO1B3 other 1 1 1 3.20504416170145 0.163184686514227 2.07971175361847e-09 274.757273218654 57.5188389021354 4.77682231531369 2.9256878415064e-06 -338.302406918702 119.508577169229 -2.83077930414695 0.00499257667089079 SUDS3 other 2.20906982469354e-05 1 0.0313662993487901 4.77682231531369 -2.83077930414695 4.33069190135757e-09 353.279161578543 54.9419704753666 6.43004170622051 6.01069080401678e-10 437.072036437277 248.831841649241 1.756495605789 0.080172069270641 GOLT1B other 4.50608492336255e-05 1 7.82591942682985e-06 6.43004170622051 1.756495605789 1.16918469897745e-19 3810.14457252185 383.258883915775 9.94143836561183 5.75172584137654e-20 77.2757370508882 1735.77709514356 0.0445193897690516 0.964524308154184 LDHB other 1.70081298160249e-15 1 8.80531709056334e-16 9.94143836561183 0.0445193897690516 7.01953188678753e-05 176.138306479312 47.8960001871406 3.67751598862325 0.000284162832452791 -115.912011418366 98.821575395032 -1.17294235550299 0.241852682161234 PRKAB1 other 0.529202508944912 1 1 3.67751598862325 -1.17294235550299 1.85592611202556e-31 430.761765519352 32.2233547464839 13.3679987359589 1.67995243822228e-31 -90.6301089252823 190.498328016234 -0.475752778877718 0.634642462996264 CMAS other 2.91640229243696e-27 1 2.65449284763503e-27 13.3679987359589 -0.475752778877718 0.0236517297492601 1.62356438319154 15.6686286299386 0.103618792782499 0.917547951849962 -87.2928153069797 33.7924164373534 -2.58320725505999 0.0103091979141944 HCFC2 other 1 1 1 0.103618792782499 -2.58320725505999 0.763639560673023 2.41688842073052 8.62543626820481 0.280204774063393 0.779539013210666 36.6177534675431 50.9919342796824 0.718108735916953 0.473322854176091 ST8SIA1 other 1 1 1 0.280204774063393 0.718108735916953 0.019737085919433 13.270793108541 6.53718703133796 2.03004641674217 0.0433285275428037 70.0106777250854 30.6203304737923 2.28641156518565 0.0230018423809992 CLEC4A other 1 1 1 2.03004641674217 2.28641156518565 3.83085685431627e-22 218.755732553418 20.3626261727465 10.7430019437376 1.38558297446345e-22 -10.1958989719477 120.379962621709 -0.0846976419488353 0.932565721381512 C2CD5 other 5.74092208187837e-18 1 2.14557523595665e-18 10.7430019437376 -0.0846976419488353 2.22589845630535e-11 224.280370969489 41.4630789756444 5.40915861798956 1.395796814781e-07 -256.815543707268 85.8411124223666 -2.99175460872001 0.00303020710039455 RAB35 other 2.603856014186e-07 1 0.00163699050437515 5.40915861798956 -2.99175460872001 1.45207587876912e-29 441.798881850939 34.2046349550797 12.9163454728035 4.59406483080837e-30 43.4693688342808 159.914574598306 0.271828686931588 0.785960716900269 PHC1 other 2.2710466743949e-25 1 7.24575905115096e-26 12.9163454728035 0.271828686931588 0.000486508580812025 505.876454445806 137.482135906008 3.67957954036775 0.000281793367687887 -65.2902291761498 286.874312650887 -0.227591758121631 0.820135237992684 COX6A1 other 1 1 1 3.67957954036775 -0.227591758121631 0.130974613977583 51.9304236726452 25.7790142840019 2.01444566888938 0.0449469249018027 23.9868946264498 57.3165603041039 0.418498501989351 0.675912923456865 RFX4 other 1 1 1 2.01444566888938 0.418498501989351 2.33744758235366e-06 65.3373811400963 15.8249022810465 4.12876995887368 4.85558893540808e-05 -63.3972420700839 35.1847807641366 -1.80183706401559 0.0726782342077588 RIC8B other 0.0201745100832945 1 0.469147002939129 4.12876995887368 -1.80183706401559 9.77216657377821e-13 794.450923342602 127.146523045254 6.24831025115676 1.6016094077526e-09 -664.037757730973 265.307715538361 -2.50289651917402 0.0129071784850015 SRSF9 other 1.20500586021259e-08 1 2.05374374356116e-05 6.24831025115676 -2.50289651917402 3.13108011575763e-38 219.685913592163 14.2709188097326 15.3939572161492 7.49293067177498e-39 66.3224697912197 89.5347536996056 0.740745543498511 0.459489068350361 FGFR1OP2 other 4.96150955142954e-34 1 1.18995231998458e-34 15.3939572161492 0.740745543498511 0.0758997849687957 -7.29337540743009 4.25360024520828 -1.71463583481925 0.087559473434118 22.4104759182032 19.2958023411593 1.1614171580935 0.246498012094255 KLRB1 other 1 1 1 -1.71463583481925 1.1614171580935 0.255691803058616 -848.047785610132 555.371667444131 -1.52699144612998 0.127946857670107 -1405.10629334959 1276.3113579803 -1.10091184612906 0.271926529861732 COL12A1 other 1 1 1 -1.52699144612998 -1.10091184612906 0.731503078262577 -34.1682807535056 54.2946787126772 -0.629311777206037 0.529675104720897 -64.5956360008243 94.699133968401 -0.682114326646096 0.495749242222092 BTN3A3 other 1 1 1 -0.629311777206037 -0.682114326646096 7.67143707306961e-05 367.084061253811 88.0635968969556 4.16839731953421 4.13953298851098e-05 -0.572639672087169 153.596326641762 -0.00372821202568703 0.997028087380105 TDP2 other 0.576201638558258 1 0.403066327091314 4.16839731953421 -0.00372821202568703 9.17382936991812e-07 225.637061806456 59.400180850794 3.79859216882232 0.000179412484475777 -237.384609983467 107.838931193575 -2.20128860102808 0.0285525154129145 FRK other 0.00818764271265193 1 1 3.79859216882232 -2.20128860102808 0.0245109852879874 214.469649028867 117.209263819951 1.82980117815876 0.0683700988802148 -258.722663032012 212.685176812733 -1.21645836775834 0.224861039601965 DSE other 1 1 1 1.82980117815876 -1.21645836775834 3.47949931311201e-08 148.970306187022 37.6523140588678 3.95647146558145 9.70313394508166e-05 -189.926876957276 68.3230046160887 -2.77983788951448 0.00581665885428153 RWDD1 other 0.000342800272327795 1 0.911609434140422 3.95647146558145 -2.77983788951448 0.791680660223954 1.00076262798361 15.8608052411111 0.0630965838600451 0.949735767130327 -17.5199108103868 28.7806446108217 -0.608739347130507 0.543203403863896 RSPH4A other 1 1 1 0.0630965838600451 -0.608739347130507 0.06494037279798 8.83168380896973 4.10989210416127 2.14888458994523 0.032532711130398 -0.894227542743178 7.65587201746268 -0.116802833263603 0.907103132187459 MAK other 1 1 1 2.14888458994523 -0.116802833263603 2.09077831672714e-11 781.009372627209 112.05696170055 6.96975324669518 2.43141374978832e-11 71.1738196318943 208.738754133353 0.340970798294717 0.733390740172008 TMEM14C other 2.44934679804584e-07 1 3.30842468933696e-07 6.96975324669518 0.340970798294717 4.01792961240725e-19 247.400217137111 27.6428954797295 8.94986624387916 5.87577573925836e-17 -46.2141549117546 51.4929503308932 -0.897485085138507 0.37025969892057 PAK1IP1 essential 5.8010867743936e-15 1 8.79133566107836e-13 8.94986624387916 -0.897485085138507 0.0515836851535929 116.761597538196 55.0537741282154 2.12086454356914 0.0348447334535779 -38.966736564356 102.553701684081 -0.379964213133857 0.704270690018665 GCNT2 other 1 1 1 2.12086454356914 -0.379964213133857 0.429026442244909 7.6358140575912 233.112774989502 0.0327558798866132 0.973893373961118 -529.880737336867 440.631960033128 -1.2025472171765 0.230201218365026 NEDD9 other 1 1 1 0.0327558798866132 -1.2025472171765 0.133542617225142 6.39629556695893 8.31454426906715 0.76928997669244 0.442388693829547 -22.0738616223981 15.1351859160294 -1.45844667814884 0.145871185575069 CEP85L other 1 1 1 0.76928997669244 -1.45844667814884 0.6106227597638 19.5710418110518 50.1907666310702 0.389933111699803 0.696892294416982 -68.6068489640492 96.7080491860214 -0.709422323596679 0.478672343624495 ADTRP other 1 1 1 0.389933111699803 -0.709422323596679 2.30753786632137e-05 189.16058798318 43.953647670253 4.30363799160179 2.34635391872195e-05 -19.1548054535563 80.0099930493927 -0.239405163324179 0.810971725982372 ASF1A other 0.183056978935274 1 0.233696850304706 4.30363799160179 -0.239405163324179 4.83131792012016e-13 106.943981744257 17.5176293612122 6.10493460839252 3.53381960584459e-09 -80.7998586801661 31.887806307848 -2.53387949927055 0.0118424387556712 MCM9 other 6.02078839205374e-09 1 4.47381562099925e-05 6.10493460839252 -2.53387949927055 0.000305894230914785 70.8003546117149 17.9293923765027 3.94884294598304 0.000100087642500135 15.8013418829679 32.620337189008 0.484401549604229 0.628490736893106 FAM184A other 1 1 0.93892217429377 3.94884294598304 0.484401549604229 1.34537015145382e-15 165.573361343578 22.0256869222898 7.51728479242205 8.12805031367675e-13 -98.9689569065215 49.3936083795245 -2.00367942641639 0.0460960672317535 RNGTT essential 1.80629396534189e-11 1 1.14686789925979e-08 7.51728479242205 -2.00367942641639 0.244487499074755 -112.098148774817 127.69268608496 -0.877874467299031 0.380786610877308 -385.161693142723 232.321229252613 -1.65788419070355 0.0984936408156689 MAN1A1 other 1 1 1 -0.877874467299031 -1.65788419070355 0.000455227554711158 251.366456211275 198.554004703534 1.26598532518443 0.206617703988187 -1093.67640707796 355.823672598857 -3.07364712159254 0.00233275076284781 SERINC1 other 1 1 1 1.26598532518443 -3.07364712159254 2.41303521772488e-09 423.244406998201 76.1357620213759 5.55907494403708 6.54927546348718e-08 -185.719033530054 141.340006816095 -1.31398772162013 0.189973933637245 HDDC2 other 2.5532325638747e-05 1 0.000781394055548655 5.55907494403708 -1.31398772162013 4.51749735108789e-05 635.790659508977 185.811624997114 3.42169473798451 0.000719501157024554 -567.314093652464 344.944552288428 -1.64465300260229 0.101213804154094 TPD52L1 other 0.347350371325148 1 1 3.42169473798451 -1.64465300260229 2.3890373472219e-09 135.860654776454 33.1193783455848 4.10214990628186 5.42349835717504e-05 -206.379670591294 61.6179105655044 -3.34934548570739 0.000925457594671821 HINT3 other 2.52879603203438e-05 1 0.522228656812384 4.10214990628186 -3.34934548570739 0.0466826934790816 342.696835383716 246.380787078893 1.39092353525919 0.165393807261939 -665.791621276539 458.386300155592 -1.45246841157894 0.147532511064602 NCOA7 other 1 1 1 1.39092353525919 -1.45246841157894 0.559774030132118 19.6110957986969 22.0860763649175 0.887939327686471 0.375366634231874 33.9809685125661 38.6027638744666 0.880272941675103 0.379497215771566 RIPOR2 other 1 1 1 0.887939327686471 0.880272941675103 0.0169174459035107 39.1596563341084 69.783357976595 0.561160389375965 0.575153630541633 -302.400856876065 123.555243796634 -2.44749512512639 0.0150226651373278 SASH1 other 1 1 1 0.561160389375965 -2.44749512512639 0.00438948521317118 143.204077272428 63.0333358450456 2.27187844896018 0.0238807383736554 -174.506394330564 115.862232978926 -1.50615424753901 0.13319659576154 UST other 1 1 1 2.27187844896018 -1.50615424753901 0.000353952579690609 34.1055317893496 15.267445780147 2.23387279578217 0.0263044158921315 -69.1113206470962 28.6046370352905 -2.41608801264743 0.0163472317696193 ULBP1 other 1 1 1 2.23387279578217 -2.41608801264743 4.68627464562456e-14 175.90548087457 22.0391462260709 7.98150160038798 4.07236120126118e-14 16.6579059745181 41.9062057700111 0.397504514389581 0.691307222308121 FBXO5 essential 6.03685899849355e-10 1 5.87682444954e-10 7.98150160038798 0.397504514389581 1.48626758829986e-15 70.1644095840663 9.75054725690613 7.19594580031086 6.04507640104407e-12 -46.6929075069951 18.5401210884824 -2.51847910184372 0.0123604301287488 MTRF1L other 1.99412522322192e-11 1 8.35852713972364e-08 7.19594580031086 -2.51847910184372 1.87543304021043e-07 153.110310066333 63.7032930502887 2.40349129118748 0.0169064618627031 -478.601980340905 124.265134710948 -3.85145826666649 0.000146361974666476 PPARD other 0.00176478249083801 1 1 2.40349129118748 -3.85145826666649 8.14415296502693e-12 262.556181282705 37.7940979447706 6.94701542199485 2.73308378037126e-11 8.77894905633148 73.724425339804 0.119077890615876 0.9053012223277 FANCE other 9.69072761308555e-08 1 3.7139875491465e-07 6.94701542199485 0.119077890615876 1.05722260399343e-08 325.601417650153 66.3483340149346 4.9074543089034 1.58870296310839e-06 -228.745514476639 129.911140281454 -1.76078444066505 0.0793945000956461 MAPK14 other 0.000107561827730292 1 0.017383587822332 4.9074543089034 -1.76078444066505 2.86727006561855e-09 359.051043335597 67.516957552764 5.31793872754118 2.19210599622071e-07 -194.027961249787 132.583972374881 -1.46343451455183 0.144503149327448 KCTD20 other 3.0195221061029e-05 1 0.00253977400722131 5.31793872754118 -1.46343451455183 2.36017509280808e-05 314.319377857853 79.1061203331378 3.97338886718457 9.08193582346727e-05 -130.307256998593 155.341769728535 -0.838842361756975 0.402294367255246 STK38 other 0.186878663848544 1 0.855336715854147 3.97338886718457 -0.838842361756975 0.000240418584474199 708.027039721899 180.944821973164 3.91294446561675 0.000115369282721233 67.4358369391398 355.242381409534 0.189830494524801 0.849584067639496 SRSF3 essential 1 1 1 3.91294446561675 0.189830494524801 4.71383686055028e-15 368.389184812759 50.340357798773 7.31796913890307 2.84017597227708e-12 -213.046109588668 99.701228516753 -2.13684538052477 0.0335027684166799 MRPL18 essential 6.24536245654307e-11 1 3.96176146372929e-08 7.31796913890307 -2.13684538052477 4.15837140752924e-10 953.935459484994 159.436903260747 5.98315346055677 7.01325508244733e-09 -338.713524686981 343.232871681413 -0.986833000661353 0.324617930978279 MCM3 essential 4.58793117392701e-06 1 8.76236090000969e-05 5.98315346055677 -0.986833000661353 7.93073744379983e-16 146.675339110324 18.7499647618192 7.82269945429447 1.18310585138567e-13 -35.2017630648553 36.5114704552795 -0.964128878566303 0.335847231760033 RNF8 essential 1.07112539915961e-11 1 1.69586392737621e-09 7.82269945429447 -0.964128878566303 0.393951074704209 -25.868411588934 38.0167771507563 -0.68044725323118 0.496802224972967 -99.2256422495241 73.3326883239895 -1.35308884097004 0.177154924026703 PHACTR1 other 1 1 1 -0.68044725323118 -1.35308884097004 0.892779722859418 46.0425859548093 97.2481326837288 0.473454704827592 0.636274234572175 43.2441011744071 190.723121231965 0.226737591620115 0.820800643064055 MDGA1 other 1 1 1 0.473454704827592 0.226737591620115 0.00276914244684351 217.258053900915 76.1376958051981 2.8534886905007 0.00466422123851581 -168.964608895305 181.882165393406 -0.928978432436403 0.353742494797334 ICK other 1 1 1 2.8534886905007 -0.928978432436403 7.86876627872172e-13 299.282992878626 42.177051323266 7.09587283816433 1.1746032683146e-11 -85.4538293328263 97.1564138059719 -0.879549028059883 0.379900540810411 FBXO9 other 9.738385146546e-09 1 1.61308266837645e-07 7.09587283816433 -0.879549028059883 0.489099046988242 -94.0928102115519 79.3027796325964 -1.18650078405166 0.236459902282406 -41.3085104288144 150.412305992597 -0.27463517799433 0.783805013381583 CD83 other 1 1 1 -1.18650078405166 -0.27463517799433 2.20962501946679e-13 457.903012689063 66.0581871225257 6.93181318826896 3.05440616034118e-11 -321.570016971728 154.036390049437 -2.08762368988603 0.0377692224424428 MDN1 essential 2.78637565429335e-09 1 4.14330195650281e-07 6.93181318826896 -2.08762368988603 5.46914732746527e-24 120.668682499653 12.4657789922714 9.67999533558757 3.10071934222252e-19 -55.8474382512564 26.0608649030959 -2.14296181108794 0.0330034984155717 SAYSD1 other 8.32349531766939e-20 1 4.72735670915245e-15 9.67999533558757 -2.14296181108794 0.00496801363042792 129.409713261858 40.044971572614 3.23160956743841 0.00138782868735969 39.3900234012098 97.0247363094776 0.405979185303512 0.68508800479672 BMP5 other 1 1 1 3.23160956743841 0.405979185303512 0.00510751756783341 17.8232208254975 18.8265056052244 0.94670892194415 0.344636759043832 -100.918577117231 37.1869854115287 -2.71381441653359 0.00708097992286805 BACH2 other 1 1 1 0.94670892194415 -2.71381441653359 0.188776544483136 13.33245289229 8.48173716465966 1.57190120767259 0.117135940814406 -5.63165473545629 15.9912168736061 -0.352171744024776 0.724982168519639 RBM24 other 1 1 1 1.57190120767259 -0.352171744024776 1.12874999129985e-08 82.5676125392633 14.7312128896926 5.60494326960923 5.12286714168619e-08 -20.9015309254958 27.7521937864699 -0.753148781185217 0.452014291378106 CAP2 other 0.000114613274116587 1 0.000615102657702261 5.60494326960923 -0.753148781185217 0.714001070005913 0.111941279167996 6.2668701185016 0.0178623901646714 0.985761679997628 -9.91695574892479 13.1142726406409 -0.75619563666782 0.450183935182287 TREML2 other 1 1 1 0.0178623901646714 -0.75619563666782 6.4240856984817e-10 144.031443176415 27.1830703955518 5.29857154032107 2.53240515122015e-07 -125.775796481217 57.8069372412865 -2.17579070062521 0.0304930375429549 ZNF451 other 7.01831362559126e-06 1 0.00292416822811391 5.29857154032107 -2.17579070062521 6.43818274455483e-09 225.338318447766 37.7195988496475 5.9740380417612 7.77946106290194e-09 -4.47674130124604 80.2136937343504 -0.055810187672843 0.955536894177035 BAG2 other 6.63712259136157e-05 1 9.70254383765131e-05 5.9740380417612 -0.055810187672843 7.5631979486483e-07 123.046561330604 25.3352430970214 4.85673497820395 2.08834479707613e-06 -36.9395790692383 53.8773871527742 -0.685623060459349 0.493576118136565 RAB23 other 0.00680234023501428 1 0.0226293042211169 4.85673497820395 -0.685623060459349 0.936069460836254 -2.00466847090664 14.0221689334011 -0.142964221899472 0.886426267193637 -9.37671844050914 25.7925785346284 -0.363543273811116 0.716486772075589 FHL5 other 1 1 1 -0.142964221899472 -0.363543273811116 0.0101344893005869 19.7609962785275 6.96261624423467 2.83815674817501 0.00488454866905378 0.850571866915945 12.8005544414104 0.0664480488567204 0.947070659745204 GPR63 other 1 1 1 2.83815674817501 0.0664480488567204 0.546817912566437 -1.26771724448447 5.20436386991916 -0.243587357873223 0.807762927353317 10.2537795787683 10.4488986180136 0.981326353486777 0.327441029145199 KHDRBS2 other 1 1 1 -0.243587357873223 0.981326353486777 5.73139143437853e-15 145.121970445268 22.1502097023683 6.55171993381855 2.91418827452648e-10 -105.347965375126 40.4827167892681 -2.60229484902194 0.00977745424318379 FBXL4 other 7.56944866738373e-11 1 3.8347803504494e-06 6.55171993381855 -2.60229484902194 1.8456451025151e-07 415.195662100457 88.2159827493509 4.706580929673 4.04266358028246e-06 -186.383789954337 159.759412507262 -1.16665295039105 0.244387619455724 CCNC other 0.00173712117048721 1 0.042880532596056 4.706580929673 -1.16665295039105 0.000794042818647867 19.4718378995434 5.09029276547413 3.82528840612367 0.000162556192183084 12.3354566210046 9.21853564804386 1.33811454356334 0.181993325670658 PRDM13 other 1 1 1 3.82528840612367 1.33811454356334 5.28670412815374e-10 262.367706155491 42.7599215830275 6.13583225698972 3.01872472709019e-09 -62.4134025938071 79.4394599582656 -0.785672543929638 0.432750830787112 E2F3 other 5.80057176941029e-06 1 3.83076167867745e-05 6.13583225698972 -0.785672543929638 0.000537738725557258 823.547030132827 263.940787934201 3.12019614921409 0.0020323921862464 -835.449419224874 530.709045921445 -1.57421364049735 0.116777663362663 PTP4A1 other 1 1 1 3.12019614921409 -1.57421364049735 1.00753885405926e-10 286.794015972924 60.9488481565253 4.70548705426551 4.07645867412465e-06 -315.194994746506 107.783512531947 -2.92433404091447 0.00374937254999603 ASCC3 other 1.1460754464924e-06 1 0.0432186148630696 4.70548705426551 -2.92433404091447 0.0395921079758563 71.9302756788962 36.097152200667 1.99268560796791 0.0473138187119448 -43.5302539631277 61.5627682301105 -0.707087338899697 0.480128864165118 BVES other 1 1 1 1.99268560796791 -0.707087338899697 0.512323742565597 -7.02271203656681 16.5175051980942 -0.425167841774137 0.67107009760381 -44.0612670302737 38.1742182944516 -1.15421530548218 0.24948407659238 COL9A1 other 1 1 1 -0.425167841774137 -1.15421530548218 4.3662081833891e-12 173.804161649073 29.7882947956212 5.83464622065652 1.53376912078891e-08 -149.202978801635 55.6412074443195 -2.68151942876049 0.00777859212188977 MED23 other 5.24468926988699e-08 1 0.000188806978769115 5.83464622065652 -2.68151942876049 0.0730706807748853 180.554336175246 88.7578289315574 2.03423560883259 0.0429015355052132 -34.9449606802277 166.33928769488 -0.210082423488119 0.833761201008067 WASF1 other 1 1 1 2.03423560883259 -0.210082423488119 0.000324104489850113 25.9937186699675 7.64594449915709 3.39967399355739 0.00077697743985057 -12.5266240316172 13.3035376007452 -0.941600979194856 0.347241789364792 GPLD1 other 1 1 1 3.39967399355739 -0.941600979194856 0.00134434571316615 145.759158829439 42.3751209114504 3.43973434634029 0.000674754955138027 -4.39073763654674 73.7304612195068 -0.0595512026362461 0.952557300301431 ALDH5A1 other 1 1 1 3.43973434634029 -0.0595512026362461 0.00105180181535498 75.0167980596392 136.116466740756 0.55112213721 0.582014305203925 -747.989438818216 231.935038082259 -3.22499543407896 0.00141778587364445 CRYBG1 other 1 1 1 0.55112213721 -3.22499543407896 0.789776028077757 -108.671456094844 159.117742385237 -0.682962531178589 0.495213946273256 -86.3537718119446 299.07250010436 -0.288738589411637 0.773002166378782 VNN1 other 1 1 1 -0.682962531178589 -0.288738589411637 0.833606013392661 24.6185969953039 45.563177618611 0.540317824217071 0.589420000190195 -7.21451868787144 85.2038994807813 -0.0846735740011378 0.932583193235841 VNN2 other 1 1 1 0.540317824217071 -0.0846735740011378 3.33878877655796e-08 237.326557344079 45.0533633564795 5.26767680952608 2.83350234622267e-07 -81.5430712378581 78.5799281229568 -1.03770865137806 0.300337595748276 ACOT13 other 0.000329371512807443 1 0.00325994444932918 5.26767680952608 -1.03770865137806 1.28243689645197e-21 325.919390553581 34.9780861514325 9.3178165649933 5.59953341891988e-18 -204.163548038069 80.8391509645768 -2.52555284910813 0.0121535519727073 SMAP1 other 1.91121570678237e-17 1 8.45809522927847e-14 9.3178165649933 -2.52555284910813 8.63426864919234e-08 4029.33918456331 724.904399732626 5.55844216982198 6.49172318331544e-08 -83.3610651689173 1355.58327658793 -0.0614946101863553 0.951010467907511 RPS12 essential 0.000829925902560368 1 0.000774722244696865 5.55844216982198 -0.0614946101863553 6.26263544005588e-14 894.163978587092 129.460814505989 6.90683109015759 3.57122814934616e-11 -434.747999817413 225.799379685091 -1.92537287048233 0.055236890071326 C6orf62 other 8.0355875331357e-10 1 4.8354429142147e-07 6.90683109015759 -1.92537287048233 8.41262347808493e-19 236.453395789386 28.2926823062261 8.3574046896696 3.95435149140064e-15 -173.455293253921 64.8991959144406 -2.67268786323015 0.0080022551297049 B3GAT2 other 1.20737972157475e-14 1 5.79510211064764e-11 8.3574046896696 -2.67268786323015 1.54780366468492e-12 350.390669034115 47.0922805259315 7.44051180195384 1.35330657366767e-12 35.4398225205934 82.1361102298617 0.431476757560267 0.666467345754008 GMNN other 1.89513080704022e-08 1 1.90112507468835e-08 7.44051180195384 0.431476757560267 0.0474457105627608 40.1958158245004 23.2078187721136 1.73199455835115 0.0844124020971143 -48.4584822890754 42.5864290865444 -1.13788555012673 0.256173271928341 EYA4 other 1 1 1 1.73199455835115 -1.13788555012673 0.0456430946936693 39.7374522245602 21.4544696740118 1.85217592549933 0.0651084177291836 -32.0677479861397 37.4970961340746 -0.855206170405255 0.393206649595579 SOBP other 1 1 1 1.85217592549933 -0.855206170405255 0.455370612791202 4.99103392769208 5.85069617304856 0.853066674472597 0.394381263890862 -5.28860262930304 10.2019966507083 -0.51838897917457 0.60461303389861 NR2E1 other 1 1 1 0.853066674472597 -0.51838897917457 4.39784500735581e-05 558.776506656018 182.736012517019 3.05783462689915 0.00245411042708166 -616.515089319336 318.641086893258 -1.93482609330247 0.0540599641668633 SNX3 other 0.338590087116323 1 1 3.05783462689915 -1.93482609330247 4.381467201932e-13 390.735795841599 63.1987991198336 6.18264589332957 2.30939003763821e-09 -333.427829551869 115.676421963576 -2.88241824817904 0.00426247519632372 HBS1L other 5.46631848113036e-09 1 2.94308666396613e-05 6.18264589332957 -2.88241824817904 0.0295687832917263 76.4670481581238 46.7381038130719 1.63607510616931 0.102984687710629 -110.625405851928 82.095504195446 -1.34752087749605 0.178938027499823 TRIM38 other 1 1 1 1.63607510616931 -1.34752087749605 2.07314671895365e-13 54.690228025821 9.00770553891133 6.07149376603966 4.28175857826986e-09 -54.146792440396 16.4776102320355 -3.28608285290816 0.00115032787378761 PEX7 other 2.61714041800709e-09 1 5.39972574305612e-05 6.07149376603966 -3.28608285290816 1.2146495851011e-06 76.5067030962405 23.7560499162259 3.22051449487756 0.00143622337367607 -110.478750325021 41.6598984165213 -2.6519207805175 0.00847694401928143 ZBTB24 other 0.0107460048793895 1 1 3.22051449487756 -2.6519207805175 1.10853265290192e-08 116.442983097191 23.7894159185968 4.89473905099806 1.69563484180374e-06 -77.1493887151217 44.2145987080752 -1.7448849694305 0.0821426564119989 FIG4 other 0.000112626917534835 1 0.0184942892195534 4.89473905099806 -1.7448849694305 0.00540550198353728 2726.36944361031 2360.01608722478 1.15523341487741 0.249012413907812 -11031.3210240383 4313.66549924206 -2.55729634714992 0.0110938925869212 PERP other 1 1 1 1.15523341487741 -2.55729634714992 0.00162614911904263 161.658701411902 70.8019395611699 2.28325244214865 0.0231898329388667 -257.880044609678 129.412627997629 -1.99269614256194 0.0472976077476735 ARFGEF3 other 1 1 1 2.28325244214865 -1.99269614256194 0.195349938008024 31.8293121961851 17.7861301642822 1.78955803776272 0.074641508956028 14.1019315869207 33.3875712965453 0.422370691826267 0.673089374133996 SLC16A10 other 1 1 1 1.78955803776272 0.422370691826267 1.38230624191626e-05 149.457336015584 73.6421135714295 2.02950905083159 0.0433835600717879 -479.34766405971 134.603931864675 -3.56117133741402 0.000435963110493362 HECA other 0.111897690283122 1 1 2.02950905083159 -3.56117133741402 0.00331240817205047 196.600010829393 75.4944729724048 2.60416429294441 0.00971792419042141 -164.408111215085 135.164814343397 -1.21635288010231 0.224908884865536 ADGRG6 other 1 1 1 2.60416429294441 -1.21635288010231 0.0382515006329741 36.9728926718855 55.4738993873087 0.666491684922806 0.505659725849729 -206.766979538116 97.8811841401947 -2.11242826038929 0.0355577880276607 PHACTR2 other 1 1 1 0.666491684922806 -2.11242826038929 7.32594699494658e-08 27.7659333973773 6.82847573067933 4.06619785915458 6.26844587636168e-05 -32.256416491532 12.0214108572355 -2.68324715581262 0.00773957163787724 EPM2A other 0.00070753996077194 1 0.600391746037922 4.06619785915458 -2.68324715581262 8.91713652226321e-13 1002.30964484643 178.303153765657 5.621379227895 4.69027771135633e-08 -801.315652820967 327.226185957654 -2.4488127393468 0.0149643301419705 SLC39A7 essential 1.10099884640384e-08 1 0.00056428731145328 5.621379227895 -2.4488127393468 0.270436967442333 -14.5270163048357 9.65409541027605 -1.50475168179639 0.133552499276623 2.24303373812239 18.0337941611074 0.124379468795304 0.901107035644156 CCR6 other 1 1 1 -1.50475168179639 0.124379468795304 7.44198737164173e-08 213.811575522884 48.3664851839685 4.42065564015294 1.42331049947414e-05 -140.80529977261 89.1075121261293 -1.58017316849004 0.115229363062834 PHF1 other 0.000718375040984576 1 0.144295218436688 4.42065564015294 -1.58017316849004 6.5346978937559e-11 516.216889554297 90.1069306547742 5.72893656240577 2.67457893570587e-08 -221.931872931536 166.007605998832 -1.33687773880131 0.182379598154689 CUTA other 7.49660542371677e-07 1 0.000325282290160548 5.72893656240577 -1.33687773880131 0.45899714085719 7.12879580523732 8.95760872508038 0.795836927468982 0.426833794901568 -11.3516010142427 16.6841970056802 -0.680380422886284 0.496853158141621 PACRG other 1 1 1 0.795836927468982 -0.680380422886284 0.000281419425080598 273.501652796805 124.545821646516 2.19599219934535 0.0289495161863733 -615.165276272655 231.852440893501 -2.65326202261215 0.00844776967443076 QKI other 1 1 1 2.19599219934535 -2.65326202261215 0.527697293438972 -0.380275223507509 5.49761608494667 -0.0691709311148085 0.944904951678776 -11.2160763857891 10.1885342305118 -1.10085279511552 0.271944822503524 C6orf118 other 1 1 1 -0.0691709311148085 -1.10085279511552 0.713672496945241 18.9984856821488 24.7218476311476 0.768489716691412 0.442867940796942 23.6960725119659 46.4780563272351 0.509833551238255 0.610584560002409 PDE10A other 1 1 1 0.768489716691412 0.509833551238255 1.02752927279838e-07 249.384632045571 79.6156206130227 3.13235807402321 0.00192273027537486 -588.886724569042 169.955869128307 -3.46493903146391 0.000615706153647196 MDFI other 0.00098406478455901 1 1 3.13235807402321 -3.46493903146391 0.127156973630169 -19.2105227855258 19.5820316311681 -0.98102807447972 0.327450669949564 -84.4804011424543 41.8069557433327 -2.02072596869068 0.044287878755052 TFEB other 1 1 1 -0.98102807447972 -2.02072596869068 0.352782144054544 -47.8619263384158 210.57144138302 -0.227295430111803 0.820365402627909 508.110749437872 395.052002746357 1.28618699792823 0.199475587369619 SMOC2 other 1 1 1 -0.227295430111803 1.28618699792823 0.00793747740068852 239.499691206902 102.952460328029 2.32631343091562 0.0207395445917981 -266.750111563958 232.53593316875 -1.14713501663581 0.252337569798045 CCND3 other 1 1 1 2.32631343091562 -1.14713501663581 1.53894882895572e-25 260.149939082537 25.3925412678536 10.2451320778941 4.93529919977821e-21 -119.25066717018 57.3534450797265 -2.07922413386694 0.0385371144228435 BYSL essential 2.36505656033915e-21 1 7.58950310941894e-17 10.2451320778941 -2.07922413386694 1.07429759005342e-11 146.34066475767 34.0238249226428 4.30112325966858 2.37703418765991e-05 -284.840611381134 64.1368763828585 -4.4411363235217 1.30613530907369e-05 FAM120B other 1.2728277846953e-07 0.20047870858972 0.236657523723421 4.30112325966858 -4.4411363235217 5.29463886631512e-25 135.044998775479 12.7066253844031 10.6279200566691 2.86259967425446e-22 -35.5984184846093 23.9527232277873 -1.48619504120984 0.138394266247013 TBP essential 8.1087394237616e-21 1 4.42643787629968e-18 10.6279200566691 -1.48619504120984 0.703808380647513 0.453212955895594 3.11010885741846 0.145722537915211 0.884249159410045 -5.05511840276829 6.98126044575776 -0.724098240145172 0.469632358841427 PRPH2 other 1 1 1 0.145722537915211 -0.724098240145172 0.000131299289743445 51.3086991032722 17.8980961000361 2.86671268365627 0.00447437140818277 -89.4641610925694 43.4692518721451 -2.05810215818086 0.0405400910432685 BICRAL other 0.958878712996378 1 1 2.86671268365627 -2.05810215818086 6.80588860308173e-42 685.249682580945 44.6471271603469 15.348124866353 1.00843305278238e-38 -71.4562208614335 108.714060852145 -0.657285914088118 0.511552885031614 PPP2R5D other 1.08070705128335e-37 1 1.60139168781842e-34 15.348124866353 -0.657285914088118 1.19214154408462e-44 371.076727587705 22.7342584805479 16.3223589590665 3.19437499740792e-42 2.48633597539732 55.3570569279037 0.044914526049235 0.964208394405075 MRPL2 essential 1.89586269755778e-40 1 5.07809793337938e-38 16.3223589590665 0.044914526049235 1.42343812897128e-19 2139.51547549625 231.13566952916 9.25653526283762 6.53418576798598e-18 -395.278446317791 562.806586682499 -0.702334435436844 0.4830712121103 PTK7 other 2.06854028902106e-15 1 9.86073974246764e-14 9.25653526283762 -0.702334435436844 7.11172349935572e-23 649.310286301725 62.4799109213482 10.3923049301254 1.60078541552578e-21 -44.4825824572883 152.240515325416 -0.292186231517978 0.770366977784644 SRF essential 1.07230566923286e-18 1 2.46729056094989e-17 10.3923049301254 -0.292186231517978 1.46752527881091e-13 346.673096949339 47.3782709133422 7.31713273334575 2.8549986132928e-12 -104.019831856566 115.443384484882 -0.901046277538648 0.368360828224088 CUL9 other 1.86067530100435e-09 1 3.9821520658208e-08 7.31713273334575 -0.901046277538648 4.54660741985976e-19 298.428548950353 31.8186824240444 9.37903540357911 2.72406576906337e-18 -2.0339783705795 77.5304019768879 -0.0262345908020164 0.979089462759706 DNPH1 other 6.55893586388969e-15 1 4.12478038751576e-14 9.37903540357911 -0.0262345908020164 0.000170012099852301 161.398766904498 53.1039381047211 3.03929939407166 0.00261505074736786 -147.994719595665 93.3416368468817 -1.58551665253564 0.114073875215163 DUSP22 other 1 1 1 3.03929939407166 -1.58551665253564 7.59532667758058e-11 175.711136828159 30.7642871870421 5.71152959793487 3.0320098590062e-08 -93.9289069901527 55.223585558746 -1.70088388937065 0.0901512884800039 EXOC2 other 8.68753465381667e-07 1 0.000367661515503092 5.71152959793487 -1.70088388937065 7.76401119489736e-07 788.38991308959 147.886991775127 5.33102948154086 2.08066797634376e-07 227.821192930885 339.862219059133 0.670333976990969 0.503224285696318 COX7A2 other 0.00697285845413732 1 0.00241419905295167 5.33102948154086 0.670333976990969 7.91508901519102e-10 753.264847048739 185.623964638525 4.05801507642405 6.51063605059628e-05 -1627.8136879784 428.363354443428 -3.80007689988658 0.000179348674197023 TMEM30A other 8.60845081292176e-06 1 0.622677231879028 4.05801507642405 -3.80007689988658 4.44178994800946e-09 200.643285052827 38.3141430442653 5.23679427779499 3.33189776693561e-07 -92.198064179892 69.074442367793 -1.33476378555436 0.183099294034908 GMDS other 4.61857318794023e-05 1 0.00381642154104562 5.23679427779499 -1.33476378555436 7.7552847487318e-27 641.025461629433 59.4062678592032 10.7905358260968 9.39058818051887e-23 -302.300810275749 137.091502299761 -2.20510246955165 0.028302715454878 SENP6 essential 1.19943233923886e-22 1 1.4550716385714e-18 10.7905358260968 -2.20510246955165 3.76046382500676e-09 2342.77067848627 433.03902648672 5.41006822755298 1.39323956248821e-07 -1632.29754271736 1053.47034889965 -1.54944801666445 0.12244972611625 VEGFA other 3.92780446521956e-05 1 0.00163413068284242 5.41006822755298 -1.54944801666445 3.39715062254512e-13 396.357230011649 60.2900313635979 6.5741752168164 2.54540790967913e-10 -176.626537944402 108.006060649558 -1.635339136361 0.103151894168277 PRPF4B other 4.25561058486227e-09 1 3.35662941049387e-06 6.5741752168164 -1.635339136361 1.17498740176195e-18 294.048090895039 32.2905305888309 9.10632577207474 2.02766471189281e-17 -42.84553640439 75.0444907473474 -0.570935134314366 0.568522037432565 TTK essential 1.68258195932312e-14 1 3.04818836138846e-13 9.10632577207474 -0.570935134314366 1.33893361808116e-12 473.518733229518 67.5493890767279 7.00996322397022 1.92079782781973e-11 -129.037615117032 156.545860019784 -0.824279959244682 0.410510766960666 SLC29A1 other 1.64193429585292e-08 1 2.62208111475671e-07 7.00996322397022 -0.824279959244682 0.0111524481581484 19.4841718121106 10.9593981241758 1.77785053443123 0.0765497039203938 -31.7412126267235 19.8955667654027 -1.59539122463803 0.111790265935966 WISP3 other 1 1 1 1.77785053443123 -1.59539122463803 8.54219940891931e-08 120.44105239185 26.2271911665089 4.59222078442193 6.7211834290579e-06 -76.0386079449945 45.7446723837447 -1.66223964415176 0.0976209269011097 BTN2A1 other 0.000821247051173503 1 0.070001125413638 4.59222078442193 -1.66223964415176 0.203261969721648 -108.68677308359 128.838154397603 -0.84359150898868 0.399641709895247 -416.475331724858 233.891320828493 -1.78063611017978 0.0760920972127985 LAMA4 other 1 1 1 -0.84359150898868 -1.78063611017978 0.226127839378314 -30.8431770211119 40.1467725263806 -0.76826043739493 0.443001410569901 -166.883493013878 97.4706614641893 -1.71214076632886 0.0880146825309729 FAM46A other 1 1 1 -0.76826043739493 -1.71214076632886 0.568136948213351 -155.36517094585 158.249152085768 -0.98177569293796 0.32708603068665 28.9846180784081 403.481752831868 0.0718362549854544 0.942785206785213 CLIC5 other 1 1 1 -0.98177569293796 0.0718362549854544 1.46699186946079e-06 255.661497234869 73.4627747111556 3.48015029707346 0.000583827660481491 -476.15846118509 152.48881810139 -3.12257952493599 0.00198691538310808 FBRSL1 other 0.0128875235732131 1 1 3.48015029707346 -3.12257952493599 1.10784910350334e-05 82.2999302719394 17.4603870743524 4.71352266828206 3.89796525909198e-06 14.5753810140454 44.2642974993199 0.32928074853711 0.742197837293497 ENPP5 other 0.0903672513727675 1 0.0413924930862977 4.71352266828206 0.32928074853711 0.602932475352293 -17.3696154468226 17.8149614621455 -0.97500157290437 0.330438705100603 -4.97160971151452 32.2211575374294 -0.154296434128392 0.87749213836216 LY86 other 1 1 1 -0.97500157290437 -0.154296434128392 1.16315916976164e-06 122.65891360839 24.1040751847227 5.08872100125759 6.74649106143806e-07 17.7243862768146 41.9618619190459 0.422392750612663 0.673073295452331 PRSS16 other 0.0103102428807671 1 0.00756821367272122 5.08872100125759 0.422392750612663 4.46037303306438e-06 81.7108926530451 18.6066297780365 4.3914934422728 1.61372416604276e-05 -45.9791399658405 44.4903324263347 -1.03346361913503 0.302304971864283 TBX18 other 0.0376455483990634 1 0.162873180078696 4.3914934422728 -1.03346361913503 8.57045214733326e-07 133.698618528059 72.3346044481112 1.84833551725533 0.0656512774070307 -388.292926748523 114.482072332363 -3.39173565640247 0.000798878156429835 ERBIN other 0.00766969762664854 1 1 1.84833551725533 -3.39173565640247 0.139738041034968 73.9807586338351 38.4547258093773 1.923840492338 0.0554180294922928 29.0248349477551 66.9488686877854 0.433537347480983 0.664968068498425 PCDHB2 other 1 1 1 1.923840492338 0.433537347480983 2.21466282868694e-12 148.045822688324 27.887852635681 5.30861320239866 2.3019743192921e-07 -116.710548014485 47.142339740094 -2.47570546260402 0.0139087868259133 HARS2 essential 2.69458026366341e-08 1 0.00266315408998903 5.30861320239866 -2.47570546260402 7.64003215382149e-07 60.0520519452815 16.8686237429411 3.55998526378959 0.000437331014832835 -55.678364132512 28.0327819298077 -1.98618760963243 0.0480124031057186 NUDT12 other 0.00686647715752543 1 1 3.55998526378959 -1.98618760963243 2.5906355481549e-16 72.7088505131776 8.01622613312749 9.0702095107702 2.7983112589135e-17 71.4295871636815 46.1114712046244 1.54906328723943 0.122564422056072 CEP72 other 3.54010347655367e-12 1 4.19970553737739e-13 9.0702095107702 1.54906328723943 7.07908530083923e-07 246.622303405242 71.8660458777047 3.43169434735455 0.000692758693875831 -257.805831844484 119.429137963332 -2.15865103140606 0.0317487970164991 MAN2A1 other 0.00638108749017648 1 1 3.43169434735455 -2.15865103140606 4.53817097065591e-08 479.412269204721 82.0667039905605 5.84173904754191 1.48219781863526e-08 -464.882454855916 515.043643753283 -0.90260788671844 0.367538559597569 SEMA5A other 0.000444150792898094 1 0.000182577127299492 5.84173904754191 -0.90260788671844 0.11220954181367 63.8520444093412 138.040710887517 0.462559515948677 0.644074585859887 -1739.63298290392 895.640238650839 -1.94233455335196 0.0531975944231389 C7 other 1 1 1 0.462559515948677 -1.94233455335196 3.61123028509983e-27 350.854104511789 28.327076008854 12.3858214099515 3.20510687193932e-28 293.036411710918 166.091114958707 1.764311184158 0.0788061521556643 PAPD7 other 5.59307346556261e-23 1 5.04099208818617e-24 12.3858214099515 1.764311184158 0.000458175559026188 69.0075396317891 17.75673031205 3.88627514295014 0.000130320714826103 -23.4662289764348 113.713932882617 -0.20636195039229 0.836675482691397 GHR other 1 1 1 3.88627514295014 -0.20636195039229 1.92198217882674e-20 1462.68697509501 144.680171189859 10.1097957174489 2.41635147379231e-20 -1008.77608350508 932.111664092487 -1.08224810649401 0.280193466361657 HMGCS1 essential 2.82512160465743e-16 1 3.70378353902885e-16 10.1097957174489 -1.08224810649401 2.72565220164099e-18 731.651850689834 77.3640153688354 9.45726313715311 1.64476543421295e-18 -707.986783988394 485.695754058639 -1.4576754646756 0.146096451308696 DAP other 3.88269156123759e-14 1 2.49445125752737e-14 9.45726313715311 -1.4576754646756 0.00023565333101165 -2.45286830003939 6.61524900088368 -0.370790018593665 0.71108254311428 -41.6737533844103 10.9005048476081 -3.82310305504381 0.000163420703165848 NME5 other 1 1 1 -0.370790018593665 -3.82310305504381 1.65895097335913e-10 283.733615155907 54.5022127035066 5.20591001872575 3.81102155433646e-07 -150.921900505172 89.8079019702173 -1.68049689608851 0.0940086707949141 BRD8 essential 1.8671493205157e-06 1 0.00434685118487616 5.20591001872575 -1.68049689608851 1.33775356537445e-06 299.453997413586 59.5134912076948 5.03169939011859 8.84740744795443e-07 79.1029228022315 98.0654090754405 0.806634302023648 0.420581926804149 KIF20A essential 0.011800324200168 1 0.00984716448957328 5.03169939011859 0.806634302023648 3.14488968873487e-17 449.737091844811 48.8698392892628 9.20275364898984 1.49762236830234e-17 -178.238844043695 314.84720296654 -0.56611220415586 0.57182940407813 NNT other 4.3946688510381e-13 1 2.25392166429502e-13 9.20275364898984 -0.56611220415586 6.42916201599471e-25 226.095708226773 19.1943072242559 11.7793106875488 1.28725798041852e-25 24.6554300773497 121.351211038403 0.203174157607272 0.839169638723331 MRPS30 other 9.8404753816815e-21 1 2.01404383616282e-21 11.7793106875488 0.203174157607272 9.98836666056313e-20 1916.30134285493 239.642758306494 7.99649176297683 3.69049703578083e-14 -683.392354265302 397.262502745474 -1.72025386121869 0.0865236585246105 HSPA9 essential 1.45420630211139e-15 1 5.32870866996394e-10 7.99649176297683 -1.72025386121869 9.56004891284528e-19 416.913940454989 60.1832653057714 6.92740645321894 3.11563259058332e-11 -248.699035085072 93.6495514732665 -2.65563509031932 0.00838478705909346 MRPS27 essential 1.37091101410201e-14 1 4.22488114697038e-07 6.92740645321894 -2.65563509031932 6.55704558595821e-23 236.773529043022 38.9632963141955 6.07683516131971 4.15822452635995e-09 -338.429010232324 64.0195179644134 -5.28634111897635 2.57730780717316e-07 PFDN1 essential 9.89130326641795e-19 0.00406054845020131 5.24809517471889e-05 6.07683516131971 -5.28634111897635 0.388697553754782 -90.1933822607541 182.630255047575 -0.493857834438542 0.62180809166704 -409.601080775251 300.074736993028 -1.36499688337565 0.173390364447118 HBEGF other 1 1 1 -0.493857834438542 -1.36499688337565 0.164941472429646 171.813436547768 199.750855540396 0.860138676667756 0.390470095208192 -345.652039570176 324.241005474833 -1.06603431932981 0.287353457811272 LOX other 1 1 1 0.860138676667756 -1.06603431932981 0.130234880704411 -16.3032905384517 16.8263449170675 -0.968914557428024 0.33345175240188 -61.5704888072593 30.4966929520329 -2.0189234584911 0.0444798141137512 GZMK other 1 1 1 -0.968914557428024 -2.0189234584911 2.32929679890621e-09 66.7009094328339 15.084258253734 4.42188858814603 1.41946150096687e-05 -52.441584451238 24.7845288670544 -2.11589999279541 0.0352687586687874 TMCO6 other 2.46788995844113e-05 1 0.143923392026937 4.42188858814603 -2.11589999279541 0.490632875787172 -2882.07956606121 3167.61620990708 -0.909857563251246 0.363700223261755 1350.19467860563 5286.05522112285 0.255425761200963 0.798586608884438 SPARC other 1 1 1 -0.909857563251246 0.255425761200963 1.20682895104388e-08 664.247486650402 118.640664574751 5.59881798564847 5.27152251541324e-08 54.1320373788604 185.726464619907 0.29146108762498 0.770920847361772 HMGCR essential 0.000122312114188298 1 0.000632582701849589 5.59881798564847 0.29146108762498 3.67093108639679e-07 97.5128199778865 46.7462885540629 2.08600132746606 0.0379102571126075 -260.482392088956 73.724934884483 -3.53316544120515 0.000482284548188012 COL4A3BP other 0.00338900357896152 1 1 2.08600132746606 -3.53316544120515 1.04648176203477e-17 411.229833659183 58.7399972819914 7.00084870084354 1.97487845117457e-11 -242.054267360401 97.7783196214945 -2.47554128867634 0.0139105208033106 FAF2 essential 1.4745974508832e-13 1 2.69491913447281e-07 7.00084870084354 -2.47554128867634 0.649822884408178 13.5635900952633 15.8121088540382 0.857797667627321 0.391756636214414 19.6665620120133 27.5559151986702 0.713696564611375 0.476024524357935 PCDHB3 other 1 1 1 0.857797667627321 0.713696564611375 0.00962578749224846 136.067698259188 44.2757162966335 3.07319021893574 0.00233209750633265 107.402133032452 77.2410315273967 1.39048030442676 0.165515555644884 PCDHB5 other 1 1 1 3.07319021893574 1.39048030442676 0.0150280679735566 66.0661607895653 23.2061830132713 2.84692061386325 0.00474960454160223 76.8471822700543 40.4842578209156 1.89819911260303 0.0587244905983246 PCDHB6 other 1 1 1 2.84692061386325 1.89819911260303 0.622045525133044 9.5053811436791 13.1458433648749 0.723071230947196 0.470255149701146 20.9978832239473 22.9335307643057 0.915597490842048 0.360686083999644 PCDHB7 other 1 1 1 0.723071230947196 0.915597490842048 0.000963419082192683 5.21134063267074 21.3259904718554 0.244365702007994 0.80713183403327 -106.403550382893 33.6848630564506 -3.15879420986743 0.00176288019918616 PDE8B other 1 1 1 0.244365702007994 -3.15879420986743 0.00249262208698745 16.1897762388354 21.3512619921089 0.758258516279687 0.448950317734117 -97.3360141921228 35.5793747046588 -2.73574268800675 0.00663189242609166 CLK4 other 1 1 1 0.758258516279687 -2.73574268800675 0.297649879235908 5.99221346029851 10.0820833189319 0.594342783206968 0.552775082980666 -17.6044638970175 17.5886598938811 -1.00089853367065 0.317762187857426 PCDHB15 other 1 1 1 0.594342783206968 -1.00089853367065 0.0807185598509331 -23.8862375677206 21.6808162556322 -1.10172224542124 0.271556370905668 -79.7411094040592 35.3788852273371 -2.25391808960797 0.0249975089207753 ITK other 1 1 1 -1.10172224542124 -2.25391808960797 0.000149920947231007 266.544905614955 84.8080887375921 3.1429184359959 0.00185774951770212 -169.251559710328 139.302685297658 -1.21499136465802 0.225423012974687 RNF130 other 1 1 1 3.1429184359959 -1.21499136465802 8.55936710327909e-15 59.2653917684155 12.6655320015854 4.6792658816856 4.54409945769367e-06 -82.9954475620605 20.6676906323049 -4.01570978773668 7.67237315602623e-05 THG1L essential 1.12435846268674e-10 1 0.047958425676499 4.6792658816856 -4.01570978773668 0.367390702481099 41.9536449801193 29.6074187335907 1.41699772471287 0.157623754395077 34.3624528048407 46.4674630550875 0.739494918500367 0.460241912189267 ARSB other 1 1 1 1.41699772471287 0.739494918500367 2.5347662248618e-11 431.578200048514 107.417277169508 4.0177726658205 7.60928071985296e-05 -598.348160426943 175.284153308843 -3.41358958657649 0.000738795511688258 CLINT1 other 2.95832566103621e-07 1 0.723186039614826 4.0177726658205 -3.41358958657649 0.0184405186898564 117.757689076389 48.8124736566842 2.41245075807101 0.0165052607745692 -9.50613862894884 76.6089011905674 -0.124086607185528 0.901338015196328 THBS4 other 1 1 1 2.41245075807101 -0.124086607185528 1.72725244468319e-13 318.896415450521 44.954461558875 7.09376565511468 1.13075299865247e-11 -29.9927975589741 73.8405652630372 -0.406183206373527 0.684927365284624 CNOT6 other 2.18531979301318e-09 1 1.55354154484863e-07 7.09376565511468 -0.406183206373527 3.05294488753917e-20 251.057136247976 39.6520360819498 6.33150680406703 9.9394687701713e-10 -263.897518441412 64.7702370331377 -4.07436394445179 6.05313518749952e-05 TTC1 essential 4.47500661615492e-16 0.910754720311178 1.28437815448154e-05 6.33150680406703 -4.07436394445179 2.74619311571649e-11 85.701529093071 17.7737577673214 4.82180134415022 2.36626522524247e-06 -66.4865327122856 27.895083993461 -2.38344981244261 0.0178352067782851 MSH3 other 3.200413457056e-07 1 0.0255320017803663 4.82180134415022 -2.38344981244261 0.469942853572127 1.61398420378277 18.7589782985377 0.0860379588961186 0.931499309274228 32.6856476589393 29.4413416745964 1.11019558891714 0.267891658067179 RASGRF2 other 1 1 1 0.0860379588961186 1.11019558891714 0.787746407878288 5.52488001024964 9.30822466603485 0.593548201560884 0.55330577995213 -0.27609058445933 15.0967765342584 -0.0182880486991915 0.985422420125368 GABRG2 other 1 1 1 0.593548201560884 -0.0182880486991915 8.7366906847557e-06 204.345008722047 85.8766349991707 2.37951811600467 0.0180225911920718 -362.529006967782 139.281164197429 -2.60285738604182 0.00975034822114463 CCNG1 other 0.0719379110982784 1 1 2.37951811600467 -2.60285738604182 0.0259595422826182 37.535914522795 14.8867783888804 2.52142629803855 0.0122618965053167 8.97262358632631 23.932605480182 0.374912108660978 0.708019065001442 POLR3G other 1 1 1 2.52142629803855 0.374912108660978 4.15983372900927e-31 646.622771576875 47.8555495178009 13.5119704630358 6.31217871757451e-32 165.94619651046 302.545714716353 0.548499576885563 0.583815992390048 DROSHA other 6.53093895454455e-27 1 9.97702968099827e-28 13.5119704630358 0.548499576885563 0.749645656811351 -22.1058549113736 53.8531350168088 -0.410484086107036 0.681786361544496 -232.186373922603 335.484609080815 -0.692092476488755 0.489492149090213 CDH6 other 1 1 1 -0.410484086107036 -0.692092476488755 4.05565208103389e-07 711.377200962316 133.408659817819 5.33231652228394 2.03539757943309e-07 257.252001622127 213.368741690755 1.20566864473041 0.228989215955925 LMNB1 other 0.00373241661017548 1 0.00236330012947976 5.33231652228394 1.20566864473041 8.90302984833353e-06 72.5633255788429 257.382800247137 0.281927640499552 0.778214169418778 -1707.83030641892 413.624310843279 -4.12894083265336 4.85712425826191e-05 ARRDC3 other 0.0732808386816333 0.733474334240131 1 0.281927640499552 -4.12894083265336 1.43961674702609e-23 534.508091243954 51.0332730996997 10.4737176116399 1.13751861114358e-21 -927.416581394167 335.694184932057 -2.76268289122098 0.00613897804317599 GOLPH3 other 2.18375464356388e-19 1 1.75496371327231e-17 10.4737176116399 -2.76268289122098 2.31705891784262e-12 669.32371100618 93.9923798622252 7.12104228010058 1.02326064314782e-11 -1079.38617923702 609.528940937026 -1.77085304198631 0.0777433894854528 SUB1 other 2.81615340874592e-08 1 1.40769966677845e-07 7.12104228010058 -1.77085304198631 0.309856651039893 80.5315179719132 77.0833088360306 1.04473353814141 0.297105423534495 -470.437801982459 499.875709792833 -0.941109545365639 0.347512326653412 NPR3 other 1 1 1 1.04473353814141 -0.941109545365639 0.164095562712484 32.691232473602 17.1398814820749 1.90731963390709 0.0575324591389826 25.5424023426228 28.0243766246287 0.911435165347275 0.362873175215057 SLC27A6 other 1 1 1 1.90731963390709 0.911435165347275 1.02183854319025e-20 731.468665804563 69.8764777738103 10.4680242781029 1.15432658536822e-21 438.258210373427 464.163513465822 0.944189273088347 0.345939510619384 TARS essential 1.50721185120562e-16 1 1.78077962324755e-17 10.4680242781029 0.944189273088347 0.000188437398000213 96.2734969701933 23.6869934972829 4.06440340270439 6.33875252951007e-05 213.169670024078 139.6268692597 1.52670951625788 0.128016963581782 IRX4 other 1 1 0.606745392124704 4.06440340270439 1.52670951625788 3.75734897366923e-08 229.082853998123 62.168595784748 3.68486453821954 0.000275915492807961 -252.66465397698 109.738189408668 -2.30243140823154 0.0220633124364072 LNPEP other 0.000369460124580895 1 1 3.68486453821954 -2.30243140823154 0.0690272636158623 35.0327724502285 54.278998086787 0.645420396194757 0.519202878718075 -151.976803379058 99.7534493725651 -1.52352429249284 0.128797962322875 PDE4D other 1 1 1 0.645420396194757 -1.52352429249284 1.98158617512135e-32 278.217679679904 20.8050176768164 13.372624046839 1.29110225149891e-31 -184.660334711495 134.785867768326 -1.37002742029969 0.171820721269317 RAD1 other 3.11921479825851e-28 1 2.04032888804373e-27 13.372624046839 -1.37002742029969 2.12423590590722e-24 374.938918714563 33.0652814676631 11.3393536081416 1.2806730923178e-24 -65.0787507957563 214.214317183166 -0.303802059785342 0.76151355213251 BRIX1 essential 3.24158399241441e-20 1 1.99823422594346e-20 11.3393536081416 -0.303802059785342 0.465085078450599 23.7823348997328 23.9608462234087 0.992549873989782 0.321818029495765 -85.0150093687862 155.206402206021 -0.54775452662022 0.584312993267665 PRLR other 1 1 1 0.992549873989782 -0.54775452662022 0.000471262990473316 501.695463831688 129.125355602411 3.88533655137767 0.000129051624381025 -262.577906373581 750.485600418254 -0.349877341053904 0.726707612412805 SLC12A7 other 1 1 1 3.88533655137767 -0.349877341053904 1.65298082325933e-11 315.173656255572 57.899601786195 5.44345119020695 1.16420579101381e-07 -153.765023259197 92.7683295504877 -1.65751635287895 0.0985637714800386 RAD50 other 1.94473193856461e-07 1 0.00137175259418737 5.44345119020695 -1.65751635287895 0.771129540166804 16.3705085674968 61.5314777326308 0.266050957505533 0.790400782403898 72.0473408034376 100.635948438152 0.715920522652157 0.474652332269173 ST8SIA4 other 1 1 1 0.266050957505533 0.715920522652157 5.60858750744555e-07 417.102775882502 77.8715549698778 5.35629185835374 1.80561745561732e-07 162.126701260458 129.215053438821 1.25470443996852 0.210659168655174 GNPDA1 other 0.00509988862052024 1 0.00210228040357524 5.35629185835374 1.25470443996852 0.188157067157543 -11.2334901425648 53.3442837533698 -0.21058470284279 0.833368441532165 -152.372400976766 88.5160759729735 -1.72140935193839 0.0863094058301875 PCDH12 other 1 1 1 -0.21058470284279 -1.72140935193839 4.70362998840913e-16 985.406925994728 211.831114145332 4.65185168840997 5.13302849004257e-06 -1490.48178303766 339.401619352183 -4.3914987379334 1.6116528407792e-05 SKP1 essential 6.3875295242596e-12 0.246889098678965 0.0539532624588374 4.65185168840997 -4.3914987379334 8.16202556693832e-28 484.026827885424 38.5927109314212 12.5419234928983 1.16522921546171e-28 210.851548751907 259.828519125845 0.811502715180328 0.417802581977503 NUP155 essential 1.26748095028985e-23 1 1.83360469345055e-24 12.5419234928983 0.811502715180328 3.03319234341262e-24 843.692330265 121.429260648781 6.94801504808034 2.71668446193665e-11 -892.894442030329 194.557290921197 -4.58936510578772 6.78683162576993e-06 PPP2CA essential 4.6237984082982e-20 0.104761532975385 3.6922458522181e-07 6.94801504808034 -4.58936510578772 0.360353855720956 -15.4949814512671 21.4149895949239 -0.723557738965229 0.469956805636482 -50.8354822449495 35.5642764995314 -1.42939734049192 0.154033360689837 FGF1 other 1 1 1 -0.723557738965229 -1.42939734049192 0.000260423252916917 125.529299968564 98.7365741162013 1.27135563586428 0.204688241468273 -468.312550085979 163.967396354304 -2.85613213662331 0.00461912563283991 NR3C1 other 1 1 1 1.27135563586428 -2.85613213662331 5.89941928619735e-10 369.699081231466 89.8535862786932 4.11446105317147 5.14276255642628e-05 -384.000029431062 143.965879661411 -2.66729887897173 0.00810314134985638 C5orf15 other 6.45632446681438e-06 1 0.496070876192879 4.11446105317147 -2.66729887897173 7.36661454806467e-21 124.476245438118 18.1928384458132 6.84204643540734 5.18984632550392e-11 -94.103028558268 28.8248960997157 -3.26464415457845 0.00123686070168977 PPWD1 essential 1.08878563020396e-16 1 6.99850776994204e-07 6.84204643540734 -3.26464415457845 3.58277709873079e-08 539.33977488902 91.7762000234326 5.87668452988154 1.25313054501205e-08 -260.061185616436 618.322167119621 -0.42059172296523 0.674394104042547 LIFR other 0.000352652749828072 1 0.00015491199797439 5.87668452988154 -0.42059172296523 2.18721789559315e-10 47.3174679734356 12.9676209549513 3.64889351237313 0.000316083033254699 -65.0027762745315 20.5283278325428 -3.16649153329892 0.00171985459486832 TRIM23 other 2.44902787769565e-06 1 1 3.64889351237313 -3.16649153329892 5.28052402067817e-11 65.0796391378032 18.6341535719728 3.49249236819041 0.000558927240191079 -105.0679581009 29.4987040981754 -3.56178216342048 0.000435255655785615 TRAPPC13 other 6.08421977662539e-07 1 1 3.49249236819041 -3.56178216342048 0.0018063021972949 3.48022531127333 1.03393723393364 3.36599282534078 0.000877481877356051 -4.53479832771806 6.83958173677321 -0.663022755227354 0.50790110440603 C9 other 1 1 1 3.36599282534078 -0.663022755227354 0.00445990104497945 84.3398588650403 41.7237402894733 2.02138778258858 0.0442153151257275 -88.2446885369843 67.8683065260952 -1.30023413068447 0.194617366120982 SEC24A other 1 1 1 2.02138778258858 -1.30023413068447 9.14530016094101e-07 0.0651455454268901 52.4355011684506 0.00124239387390631 0.999009620719619 -401.607039946235 85.292177581876 -4.70860343037571 3.97291173863137e-06 TXNDC15 other 0.00816492398368814 0.061615888154434 1 0.00124239387390631 -4.70860343037571 1.65761661107363e-17 62.5602374481477 6.83283296447541 9.15582713252389 1.71192084733715e-17 -40.5730138749822 44.4721500731869 -0.912324090654758 0.362449825245304 TTC33 other 2.32729372194738e-13 1 2.57490014647981e-13 9.15582713252389 -0.912324090654758 7.37923440741009e-14 360.361258813154 51.8657161491305 6.94796650984245 2.73540835219418e-11 -45.2653871952129 83.9698144176883 -0.539067372116017 0.590281313792121 RARS essential 9.44615796492566e-10 1 3.71687286896146e-07 6.94796650984245 -0.539067372116017 0.000634299985941813 151.046014927414 77.3186346445955 1.95355253777715 0.0517753973059366 -250.584590518089 124.459503707411 -2.01338253049107 0.0450556939764736 WWC1 other 1 1 1 1.95355253777715 -2.01338253049107 1.60766485407975e-15 1292.28539841223 231.489558412261 5.5824781354103 5.71846412528321e-08 -1192.91566346032 376.54352651307 -3.16806844219885 0.00170889220154545 H2AFY other 2.15475320392309e-11 1 0.000685129186850181 5.5824781354103 -3.16806844219885 6.52029701138851e-06 266.258229967276 62.7623000380989 4.24232747693517 3.03604136108274e-05 -34.5673616924145 104.84681591562 -0.329693957709065 0.74188497423745 TCERG1 essential 0.0541771478676271 1 0.299475119857202 4.24232747693517 -0.329693957709065 0.327286720865209 573.138569486279 508.436961441182 1.12725590968386 0.260624096686177 1192.14656355178 854.898728532529 1.39448863796785 0.164303823752949 DPYSL3 other 1 1 1 1.12725590968386 1.39448863796785 3.31710576448565e-08 365.218149763676 72.6407996679694 5.0277275502615 8.99805198394173e-07 -72.0777541733687 120.740939799607 -0.596962010507749 0.551027494271602 SMAD5 other 0.000327431510012379 1 0.0100094330269368 5.0277275502615 -0.596962010507749 8.53734015350666e-14 1047.23753242683 266.342308635457 3.93192331249252 0.000106901396901502 -1988.60786385092 441.25301271339 -4.50672926088913 9.77475027535087e-06 CSNK1A1 essential 1.09081595141355e-09 0.150404082486824 0.999421159632145 3.93192331249252 -4.50672926088913 1.53098296032004e-09 272.69931581372 52.8658730999689 5.15832426143891 4.79630813950667e-07 -108.368501618983 88.2215224323233 -1.22836807426571 0.220366736645156 HMGXB3 other 1.63799866924641e-05 1 0.00542894118310759 5.15832426143891 -1.22836807426571 1.17288696074664e-12 618.256217448229 172.10213122683 3.59237978658944 0.000388786235660521 -1210.04275466008 278.90749653477 -4.33850925376341 2.02384815688669e-05 ERGIC1 other 1.44136078606155e-08 0.308980898111891 1 3.59237978658944 -4.33850925376341 0.668667743092969 -207.111726737176 270.581726604594 -0.76543131473114 0.44467597554998 24.3739458662913 451.541428593904 0.0539794231997527 0.956991038171145 PDGFRB other 1 1 1 -0.76543131473114 0.0539794231997527 0.355186763413747 -8.40493927601723 6.66570038607286 -1.26092365231091 0.208412871591519 -13.4570864250777 11.1235888419938 -1.20977920131986 0.227410155261291 CDX1 other 1 1 1 -1.26092365231091 -1.20977920131986 1.91320756352015e-11 641.784462861771 197.162618316542 3.25510215040558 0.0012769908614739 -1345.95374487414 319.520344651805 -4.21241954511812 3.43907283410974e-05 ATP6V0E1 other 2.24572303805996e-07 0.521569786021084 1 3.25510215040558 -4.21241954511812 4.15931021738187e-10 65.2418154404632 14.6099399831097 4.46557723822877 1.17151901706633e-05 -56.613753133133 23.676765396018 -2.39111011095521 0.0174775491190606 BNIP1 essential 4.58855103181567e-06 1 0.119658952403155 4.46557723822877 -2.39111011095521 0.00199332949630706 588.938427335324 184.603416296737 3.19028996943721 0.00158778948840587 41.576323598613 299.166990693618 0.138973633094408 0.889573822735111 STC2 other 1 1 1 3.19028996943721 0.138973633094408 0.000686321304143401 3.21466482280061 52.1510967038391 0.0616413656851048 0.950893703861739 -283.942753699736 84.5156984374569 -3.3596451185913 0.000892119110557018 CPEB4 other 1 1 1 0.0616413656851048 -3.3596451185913 0.0580788259994523 158.000428111912 78.6314813534716 2.00937875507716 0.0454810593790074 -33.2101103834485 129.903239611198 -0.255652672580352 0.798411556264544 HRH2 other 1 1 1 2.00937875507716 -0.255652672580352 8.50979682559612e-05 669.068073063756 166.212434071069 4.02537918900626 7.38770910932207e-05 58.6362459413934 279.961725518849 0.209443793906912 0.834259166636179 DBN1 other 0.635937116776798 1 0.702866644660901 4.02537918900626 0.209443793906912 5.30233202603634e-15 81.7475836866909 11.4157319694669 7.16095857062318 7.44103877798285e-12 -19.1179556259679 19.1239108761707 -0.999688596634793 0.318346484180678 ZNF346 other 7.01445503724348e-11 1 1.02664012019829e-07 7.16095857062318 -0.999688596634793 0.127196426161925 0.697766189940101 7.76130541668473 0.0899031995880603 0.928430060896759 -22.7890880768443 12.9194320195397 -1.76393885136571 0.0788607100229678 UNC5A other 1 1 1 0.0899031995880603 -1.76393885136571 1.25379425169731e-25 100.011619707013 8.54007436600092 11.7108605172306 7.41241237888991e-26 -145.380938144031 89.3937258360583 -1.62629912540673 0.105061265027762 EHHADH other 1.92795942083495e-21 1 1.16070965441037e-21 11.7108605172306 -1.62629912540673 0.194842005753292 -8.89177211639402 7.81278739850947 -1.13810496342066 0.25608181343482 -30.0147295705343 17.1228328525589 -1.7529067665955 0.0807487549202192 CNTN3 other 1 1 1 -1.13810496342066 -1.7529067665955 5.17439957491514e-11 609.060248666132 86.4456381707794 7.04558681680261 1.70433078592714e-11 -674.273646780748 560.93856167073 -1.20204545177364 0.230456649027102 SMC4 essential 5.96504782996217e-07 1 2.32982018436241e-07 7.04558681680261 -1.20204545177364 0.000191063603909303 75.6324337083952 55.2899784246184 1.36792300998112 0.17246521840824 -468.170996931313 139.284156540359 -3.36126526203757 0.000887111518738838 SELENOK other 1 1 1 1.36792300998112 -3.36126526203757 5.37831961577046e-13 86.3346762137065 14.9000224144764 5.79426485491902 1.89425825730488e-08 -126.098103706036 37.5355012529492 -3.35943572076659 0.000892768243343565 ACTR8 essential 6.69439442574949e-09 1 0.000231914038441836 5.79426485491902 -3.35943572076659 1.12052329614271e-29 114.285878891107 8.83685368653424 12.9328698816478 5.18849095603425e-30 -79.6532593989313 81.2705271230873 -0.980100193989062 0.327927223433432 TBCCD1 other 1.75350690613372e-25 1 8.18173138857041e-26 12.9328698816478 -0.980100193989062 1.03665740063984e-16 489.281408498944 57.7115325527859 8.47805259809073 1.49468732601483e-15 -433.90838077465 219.47310820341 -1.97704577260782 0.0490498892720735 TIMMDC1 other 1.42975788696246e-12 1 2.20137549375465e-11 8.47805259809073 -1.97704577260782 1.69395559076144e-06 164.114659899662 37.7312771437061 4.34956546195355 1.95798312862018e-05 -147.72349943255 106.031400054242 -1.39320521427595 0.164743131815782 CRBN other 0.0148153355967996 1 0.196229069150315 4.34956546195355 -1.39320521427595 0.0391252966462699 106.672599344224 41.9301121032884 2.54405709866581 0.0115255929302075 -22.8818173081006 352.121142801685 -0.0649827986074316 0.948236689615952 BCL6 og 1 1 1 2.54405709866581 -0.0649827986074316 0.00832418562110954 11.8383480522235 48.4235001157978 0.244475265602731 0.80704775437517 579.339752339916 186.55727926209 3.10542560778889 0.00210158030582818 HGD other 1 1 1 0.244475265602731 3.10542560778889 0.896604974791287 -0.979514538568929 22.3736153256388 -0.0437798953952009 0.965113073410898 -80.4805884356766 172.226132128332 -0.46729603365712 0.64067501943544 CLDN16 other 1 1 1 -0.0437798953952009 -0.46729603365712 6.53692372019555e-07 40.427139513585 9.30503882510517 4.34465027749393 2.01002393800578e-05 -62.681202449434 33.5168640965681 -1.87013923107001 0.0626012486090098 ARL6 other 0.00590937904305677 1 0.201163195715619 4.34465027749393 -1.87013923107001 5.33187747480167e-07 77.9484449959829 16.4895472540776 4.72714282538639 3.6520339033686e-06 -162.084614245782 80.8918514931248 -2.00371992053561 0.046088060289539 NPHP3 other 0.00485840675503928 1 0.0388247724267116 4.72714282538639 -2.00371992053561 0.649251643294283 -7.52285798178587 19.0711969947634 -0.394461762617811 0.693550398831993 -67.2773725971813 75.0319658017416 -0.896649473038593 0.370701806712749 CD86 other 1 1 1 -0.394461762617811 -0.896649473038593 0.00360619026636703 118.897365648708 50.8830020377056 2.33668142380047 0.0201792596948704 -520.678410218796 257.001533697247 -2.02597394158809 0.0437398881672736 AMOTL2 other 1 1 1 2.33668142380047 -2.02597394158809 1.72291078791107e-16 427.742971215953 47.5202676005796 9.00127446274601 4.23694178025471e-17 144.316857933206 173.523992640287 0.831682441933969 0.406328624801317 NIT2 other 2.36383360101399e-12 1 6.34736248099958e-13 9.00127446274601 0.831682441933969 1.41508158009431e-13 964.682437595152 118.98448412077 8.10763222384518 1.79259275617871e-14 350.185332422745 468.412574874539 0.747600195226483 0.455349556079449 FAM162A other 1.79545550882366e-09 1 2.60284468197149e-10 8.10763222384518 0.747600195226483 2.11389481709416e-15 140.642015945649 19.3889223007684 7.25373044277327 4.23145877636651e-12 -131.533702029703 53.8754882871378 -2.44143869896219 0.0152665666882594 OGG1 other 2.82458625460122e-11 1 5.87749624037308e-08 7.25373044277327 -2.44143869896219 6.93280552249324e-24 758.092005376145 66.5300663900936 11.3947279254335 7.78688088115589e-25 266.348149895426 261.912466441646 1.01693574771008 0.31009102057058 KPNA1 other 1.05420240775032e-19 1 1.21638866244536e-20 11.3947279254335 1.01693574771008 2.11326589183979e-12 328.518236823798 44.0137494492577 7.46399116036542 1.17784031212105e-12 -187.921724977987 225.469725352479 -0.833467662606177 0.405323227210709 PCCB other 2.57332387649332e-08 1 1.65733910318553e-08 7.46399116036542 -0.833467662606177 8.00739579724493e-15 483.577758620776 78.7604012249543 6.13985900401381 2.96527295186832e-09 -277.793849272729 146.427905388658 -1.89713735599367 0.0588847539870496 UBE3A other 1.05289247337974e-10 1 3.76411748510164e-05 6.13985900401381 -1.89713735599367 1.53806388881725e-21 199.581472467446 19.6639977213887 10.1495878556963 1.07985832785909e-20 -212.254197171649 101.529343591996 -2.09056997378619 0.0375087908539016 ARMC8 other 2.28925429211559e-17 1 1.65866239159156e-16 10.1495878556963 -2.09056997378619 1.66278376903066e-08 119.505658645166 21.6457391184165 5.52097842403954 7.96061735690192e-08 -226.548529851647 111.292379573341 -2.03561583210064 0.042772549672707 CEP70 other 0.00016705988527451 1 0.000945880554347087 5.52097842403954 -2.03561583210064 0.0346011782116818 393.821423665003 206.304221708155 1.90893535965598 0.057334484751432 -1658.69054904666 1061.84028893427 -1.56209042577527 0.119442343473002 RBP1 other 1 1 1 1.90893535965598 -1.56209042577527 3.39722928476534e-18 593.103386669647 61.4826317687209 9.64668182879228 4.11359084879131e-19 54.9455410092867 315.200240490681 0.174319476799102 0.861745027784633 SLC25A36 other 4.82984087415088e-14 1 6.26582158087892e-15 9.64668182879228 0.174319476799102 0.128763100607019 1.80124938631093 0.886211614855439 2.0325273965234 0.0430898498514591 1.00321319135249 4.6906004929741 0.213877347443077 0.830805941096725 GRK7 other 1 1 1 2.0325273965234 0.213877347443077 1.56976850272443e-08 388.227033825044 63.2177373851222 6.14110928171893 2.94488489187159e-09 -69.0081506262302 335.055080493336 -0.205960615563932 0.836978045029051 RNF7 other 0.000157918711374077 1 3.73912034720936e-05 6.14110928171893 -0.205960615563932 1.14149048092293e-09 305.332046222746 47.9432585334277 6.36861272184613 8.29681972882982e-10 -324.886856562659 253.387164319062 -1.28217566756288 0.20089316549555 TFDP2 other 1.22881450271353e-05 1 1.07493596406719e-05 6.36861272184613 -1.28217566756288 1.2705121816998e-11 164.681341081605 23.0833601069829 7.13420144720558 9.16277799698016e-12 -153.754889853539 123.98467404432 -1.24011206254878 0.216022672292387 XRN1 other 1.50199950120551e-07 1 1.26244755242393e-07 7.13420144720558 -1.24011206254878 0.167532286353884 -14.8669442047493 36.2755438778275 -0.409833805795433 0.682252839850696 -172.989919656985 92.0263554541562 -1.87978670678925 0.06121388840674 KAT2B other 1 1 1 -0.409833805795433 -1.87978670678925 0.329631916077094 36.1130259663229 26.4497926098903 1.36534249999447 0.173343977513574 -122.446692266787 218.555376689904 -0.560254769849562 0.575795616081945 BCHE other 1 1 1 1.36534249999447 -0.560254769849562 1.76829569651587e-16 344.572318611638 37.8318646646017 9.10799194452727 2.39068386670039e-17 -206.94623284792 345.356094488083 -0.59922565766408 0.549548231372284 PDCD10 other 2.42504071820186e-12 1 3.59080716778399e-13 9.10799194452727 -0.59922565766408 0.168328136801609 984.861358092682 521.090013625996 1.89000236492644 0.0598207970380932 916.956566212907 1312.70774736248 0.698523009447666 0.485446960148832 WNT5A ts 1 1 1 1.89000236492644 0.698523009447666 4.38884216294387e-05 292.412645391292 108.531504757394 2.69426509882948 0.0074915849790936 -709.633741265284 267.502589861718 -2.65281073215822 0.00844994640244493 PFKFB4 other 0.337940846546678 1 1 2.69426509882948 -2.65281073215822 5.49910651033407e-10 81.3323393552613 11.9710156433366 6.79410517690982 6.94206619219064e-11 81.8602119188405 94.5503726954037 0.865784127393713 0.387377206264739 FGF12 other 6.0264708246751e-06 1 9.32458330935047e-07 6.79410517690982 0.865784127393713 5.80441000761404e-05 292.005618334179 65.4371718441986 4.46238139737188 1.18633065562215e-05 141.247979092605 156.115300037471 0.904767047552047 0.366386558605521 PRKAR2A other 0.441889733879657 1 0.121100633325909 4.46238139737188 0.904767047552047 0.612461014587659 -31.9099765017226 37.4555044047414 -0.851943579691405 0.395000422753667 -172.185851856922 288.442469266149 -0.59695041543291 0.55104071827282 HES1 other 1 1 1 -0.851943579691405 -0.59695041543291 1.76964280415043e-06 146.869172277564 56.1589855325784 2.61523905541996 0.00941230927925218 -467.129004623239 133.826659560075 -3.49055267581825 0.000561891261099113 USP4 other 0.015457829894254 1 1 2.61523905541996 -3.49055267581825 1.52815001247628e-32 794.929757121387 57.3597541686206 13.8586674340432 2.36460324669532e-33 -24.161184499934 441.701408380898 -0.0547002659296454 0.956417710533741 ACAP2 other 2.40622500964515e-28 1 3.74293047919402e-29 13.8586674340432 -0.0547002659296454 1.7860580577794e-19 456.578994625855 45.1883661588928 10.1039057933721 1.70959758100167e-20 251.337108136828 461.542206422799 0.544559315787879 0.586518061927736 ECT2 essential 2.59121303022635e-15 1 2.62269364901467e-16 10.1039057933721 0.544559315787879 0.0442853248404298 -447.238040345822 394.956963021486 -1.13237158024605 0.258475488684761 -2331.89195965419 936.861449121295 -2.489046765497 0.0134068077870458 GNAI2 other 1 1 1 -1.13237158024605 -2.489046765497 1.68464643870181e-24 1109.34709429532 102.084850915125 10.8669120280898 5.1062631234886e-23 -456.832268708754 378.539124416632 -1.20682972840068 0.228565847253662 TFG other 2.57228664725379e-20 1 7.92900537815309e-19 10.8669120280898 -1.20682972840068 0.286608206760746 -74.1074207492798 57.1216013610525 -1.29736245104306 0.195605778850298 -174.187579250722 135.49584192122 -1.28555663982661 0.199691267188 HYAL1 other 1 1 1 -1.29736245104306 -1.28555663982661 0.00895781435620476 90.5258645533137 51.3451011088196 1.76308669373258 0.0790087356830078 -222.420864553315 121.793639140048 -1.82621084420968 0.0689146466401935 TUSC2 other 1 1 1 1.76308669373258 -1.82621084420968 2.53716329917685e-05 87.8641016500307 21.5602668141029 4.07527895677791 6.04239378907482e-05 -43.2599380147257 51.030283151589 -0.847730707004291 0.397336043149421 NPRL2 other 0.200334414103004 1 0.579525988310166 4.07527895677791 -0.847730707004291 9.92224089608005e-08 1354.72947369098 262.557470599716 5.15974453363142 4.86429337740793e-07 -1253.8357298483 967.554972606375 -1.29588061179691 0.196148428915502 RPL24 essential 0.000950749122662391 1 0.00550200223918611 5.15974453363142 -1.29588061179691 0.0692765522226953 37.5193522102262 19.3707068549218 1.93691187891231 0.053795401274659 -26.087827023252 45.8478860292441 -0.569008285498961 0.569821787947899 CYB561D2 other 1 1 1 1.93691187891231 -0.569008285498961 0.856974345875963 2.69037183365231 37.882278642237 0.0710192715454205 0.943434798858386 -38.2579926058537 79.9953305899274 -0.478252822054978 0.632855848598132 C3orf14 other 1 1 1 0.0710192715454205 -0.478252822054978 4.51721074078151e-37 1083.02261594968 70.6612669653877 15.3269628816616 3.53747198471199e-38 440.843809660498 769.273684861471 0.573064981080022 0.567097887853122 FXR1 other 7.15255148695344e-33 1 5.6167980173257e-34 15.3269628816616 0.573064981080022 4.06290744515342e-06 172.280437854469 40.2066041647796 4.28487909967249 2.5546331838521e-05 -275.332024581111 156.905214972478 -1.754766561643 0.0804462506551467 CBLB other 0.0344047002455591 1 0.253700621488352 4.28487909967249 -1.754766561643 4.37631720365431e-14 323.228238058948 44.6026983005561 7.24683147824081 4.59101122904212e-12 -423.937983113777 175.819965169534 -2.41120502273446 0.0165754882446323 BBX other 5.64326103411223e-10 1 6.36727347355851e-08 7.24683147824081 -2.41120502273446 0.000217330585968607 146.319798596211 47.4269177183666 3.08516356608068 0.00224567070806271 -389.040204138234 187.677311389302 -2.07292080890504 0.0391282862852387 IFT57 other 1 1 1 3.08516356608068 -2.07292080890504 0.000308699361853934 143.240251324663 35.1164975851376 4.07900164238722 6.00616689180899e-05 86.9991683988231 379.548376856306 0.229217600979915 0.818878623070902 GNB4 other 1 1 0.576231651600154 4.07900164238722 0.229217600979915 0.607584065819621 -1.31177694638219 4.85423895222985 -0.270233286678153 0.787187226280755 -19.164112338884 19.2091444948132 -0.997655691749241 0.319339603011759 HHLA2 other 1 1 1 -0.270233286678153 -0.997655691749241 0.261060456477166 -1.43786911761083 23.819689948911 -0.0603647285373907 0.951911882563597 -282.293124706936 172.212217453579 -1.63921659497259 0.102386931255004 IQCG other 1 1 1 -0.0603647285373907 -1.63921659497259 0.000354118923754493 263.345073360375 70.0670998353033 3.75846972372743 0.000211969319770248 23.1700824583015 151.054775512294 0.153388612705037 0.878213137051728 GBE1 other 1 1 1 3.75846972372743 0.153388612705037 0.541717962634634 3.1678420741526 7.6259345459258 0.415403784949222 0.678175046865317 -27.9776979765095 30.1464553134423 -0.928059292066559 0.354202650099422 MORC1 other 1 1 1 0.415403784949222 -0.928059292066559 2.26541858429332e-19 331.895899023606 33.89118374968 9.79298632573551 1.41908244158904e-19 -47.8725492373058 130.03687000592 -0.368145966871751 0.713052853767437 UMPS essential 3.28327115421631e-15 1 2.16764842952726e-15 9.79298632573551 -0.368145966871751 3.07800216482702e-20 622.709684086116 60.8649956365898 10.2309985825706 6.70267153654759e-21 -206.269444589246 441.125374765665 -0.467598230319035 0.640459141574336 NCBP2 essential 4.51142777298696e-16 1 1.03006656173663e-16 10.2309985825706 -0.467598230319035 5.38551879345335e-24 252.866768289985 23.0988862182943 10.9471411695043 2.60750314115263e-23 -111.395985254206 87.4968038233194 -1.2731434793795 0.204066270939985 SNX4 other 8.196759603636e-20 1 4.05362438323588e-19 10.9471411695043 -1.2731434793795 0.000503548956872851 36.1056510475549 12.2564302338653 2.94585375665035 0.00350050400280794 -88.5519728198785 45.6756430430269 -1.93871321606708 0.053574432612313 C3orf52 other 1 1 1 2.94585375665035 -1.93871321606708 0.0124726347042547 197.209072978303 69.5753061571258 2.83446935228621 0.00493565056484306 46.1263971071665 145.183904828035 0.31771012883144 0.750949490713879 FRMD4B other 1 1 1 2.83446935228621 0.31771012883144 9.68751637386799e-14 245.159029010397 32.4619093166762 7.55220608309861 6.6307540745807e-13 -216.199577934755 123.925606717924 -1.74459164381469 0.0821938400907674 SLC41A3 other 1.23525521283191e-09 1 9.37654933686457e-09 7.55220608309861 -1.74459164381469 0.0722887892747239 4.52676712873467 2.06765390981229 2.18932535433148 0.0294293545737074 -2.40948712605188 7.89341325417801 -0.30525287964323 0.760408749771796 ROPN1B other 1 1 1 2.18932535433148 -0.30525287964323 9.72509030971985e-06 768.96763526579 216.022512471839 3.55966434454851 0.000438359083973941 -2189.77232827343 828.096163593591 -2.64434545713959 0.00866224343401207 PLXNA1 other 0.0797943659912513 1 1 3.55966434454851 -2.64434545713959 1.14286310672229e-21 719.815623443965 67.8593145337757 10.6074697097875 3.16221694837795e-22 68.5808038490687 260.403358773407 0.263363745276208 0.792469628581044 ATP6V1A essential 1.70423746474427e-17 1 4.88941984558198e-18 10.6074697097875 0.263363745276208 1.58643947340811e-05 105.488428972618 24.4095628708288 4.32160254285766 2.17712347480074e-05 -115.112274952185 93.5711057937303 -1.23021176222861 0.219684633347585 ABTB1 other 0.127731865088709 1 0.217364007724106 4.32160254285766 -1.23021176222861 0.00265699188200414 216.483172719753 68.7737873769826 3.14775703035087 0.00182904287091437 -228.208060887388 263.63599252233 -0.865618001184184 0.387465335113854 PODXL2 other 1 1 1 3.14775703035087 -0.865618001184184 0.917888225627817 157.908578168938 402.344321939355 0.392471248029044 0.695018555715535 306.66864941227 1530.08861484066 0.200425417480938 0.841298209850293 UPK1B other 1 1 1 0.392471248029044 0.200425417480938 0.723126004013334 7.39408837096373 10.0486202527307 0.735831207170394 0.462467485275465 -2.50341911467213 25.9933104823669 -0.0963101301148374 0.923345187163204 CSPG5 other 1 1 1 0.735831207170394 -0.0963101301148374 7.13818360760244e-07 86.5609879100046 16.691762369089 5.18585072061082 4.20376936211844e-07 -5.04616791511456 43.216319591442 -0.116765332236062 0.907132184104911 KLHL18 other 0.00643221724881056 1 0.00478010614166488 5.18585072061082 -0.116765332236062 5.3731009753829e-09 462.170569605229 77.3225716530052 5.97717535416796 7.13046397081093e-09 -81.6661648118391 199.836526773721 -0.408664852869023 0.68310837253298 SCAP essential 5.56492068020408e-05 1 8.90594949954285e-05 5.97717535416796 -0.408664852869023 0.490142266655358 4.50017671276052 9.33291834619386 0.482183229921407 0.630066434542199 -35.4102203655884 35.6290678166229 -0.993857615019264 0.321182036346843 EFCC1 other 1 1 1 0.482183229921407 -0.993857615019264 5.85703411875898e-11 33.4106836395823 4.75020282189486 7.03352780760944 1.65399037688079e-11 -3.18159305757653 18.1342311382191 -0.17544681289912 0.860860063275228 KIAA1257 other 6.73207501610157e-07 1 2.26199723942217e-07 7.03352780760944 -0.17544681289912 6.9401740189062e-07 18.1570669423811 6.02681873153676 3.01271163962007 0.00283405978910468 -118.066836667603 29.6682319243027 -3.97957104315639 8.86956436924988e-05 NEK11 other 0.00626142499985718 1 1 3.01271163962007 -3.97957104315639 3.75498323053701e-17 628.65583827102 69.9474076171937 8.98755021360492 4.44243583877149e-17 -338.105854818063 341.992520856271 -0.988635230886112 0.323723510672763 MRPL3 essential 5.23707511162997e-13 1 6.65388039931194e-13 8.98755021360492 -0.988635230886112 0.00819753551276621 52.1728296096772 19.6659647252015 2.65295043180968 0.00845357584179467 -139.088112377202 112.187699971216 -1.23978040741443 0.216137069786336 PLSCR4 other 1 1 1 2.65295043180968 -1.23978040741443 8.21290001144129e-07 100.116095044966 25.0827286552687 3.9914355579466 8.46839008423559e-05 -127.500396755423 59.2359371470952 -2.15241630159092 0.0322508917662757 HEMK1 other 0.00735875841025139 1 0.800093495158579 3.9914355579466 -2.15241630159092 0.15861141899543 -67.5344295538706 55.1655189013567 -1.22421452564656 0.221938439255785 -235.621583494974 130.280132406617 -1.80857648163556 0.0716292311822424 CISH other 1 1 1 -1.22421452564656 -1.80857648163556 2.38720609655491e-05 181.192999470993 56.1508120986317 3.22689900108157 0.00140573314749876 -286.309057779343 132.607023021565 -2.1590791441927 0.0317249426286894 MAPKAPK3 other 0.188995106664253 1 1 3.22689900108157 -2.1590791441927 3.64736111698642e-21 232.012890625 22.0126777579269 10.5399667035715 5.12859595808453e-22 173.048852539063 68.7483318331595 2.51713529513738 0.0124044461350493 ACVR2B other 5.41049548093766e-17 1 7.92368075524059e-18 10.5399667035715 2.51713529513738 3.32508996735485e-08 140.749144691511 33.8870549236638 4.15347822372206 4.38322301691781e-05 -203.023175972501 90.0532275229846 -2.25447972889903 0.0249587924374056 WDR48 other 0.000328186379777923 1 0.426005445014242 4.15347822372206 -2.25447972889903 9.64665749328022e-13 264.740338801563 35.1099148871484 7.54032983709875 7.2131248757283e-13 -306.448682455458 222.96629628567 -1.37441706464383 0.170456173052245 COMMD2 other 1.18981873522118e-08 1 1.01914241369165e-08 7.54032983709875 -1.37441706464383 1.67268508370301e-11 120.483240334715 31.3783762403181 3.83969009141734 0.000153177779606096 -341.886027903567 83.386533920891 -4.10001485645051 5.45458447798487e-05 GORASP1 other 1.96724492694311e-07 0.822169518366659 1 3.83969009141734 -4.10001485645051 0.198456449644131 -0.412116364975389 8.73907221320347 -0.0471579081761953 0.962423163861949 172.329555303465 95.5977785638381 1.80265229895888 0.0725875620191178 PEX5L other 1 1 1 -0.0471579081761953 1.80265229895888 2.71164532079426e-13 259.756727333834 33.1556313027043 7.83446784536561 1.0742593552112e-13 73.2229828958043 78.3685272057213 0.934341699488499 0.350959429462888 RRP9 essential 3.40935166183463e-09 1 1.5407027672439e-09 7.83446784536561 0.934341699488499 2.64148613402232e-27 1998.70508472454 163.449110404364 12.228302006538 1.45280010912657e-27 4994.53841251951 1856.01576301878 2.69099999689441 0.00757680015680945 ABCC5 other 4.09377521050779e-23 1 2.28234897143784e-23 12.228302006538 2.69099999689441 0.178142807163582 24.0020526876619 18.8470050942786 1.2735207831481 0.203936739343306 177.463492318143 123.510959309256 1.43682385199354 0.151934432651867 AADAC other 1 1 1 1.2735207831481 1.43682385199354 0.000683249190343329 184.154102157569 74.1008329374107 2.48518262018883 0.0135521136415115 -345.31287673435 175.148923843547 -1.97153867210056 0.049679379828297 ABHD14B other 1 1 1 2.48518262018883 -1.97153867210056 2.81151992426916e-07 233.61636497228 45.7954392646948 5.10130197948297 6.32219828731761e-07 -23.7610580455528 119.631099780161 -0.198619406569171 0.842708304569643 EIF1B other 0.00261443237757789 1 0.00710298977580133 5.10130197948297 -0.198619406569171 1.31334387676751e-05 75.6569406796376 50.5347591456615 1.49712676895449 0.135524044480603 -459.210646101691 119.446817669804 -3.84447786102702 0.000150604220841169 ABHD14A-ACY1 other 0.10648592152831 1 1 1.49712676895449 -3.84447786102702 3.44599688996115e-07 186.889786953384 33.3089904577122 5.61079109229239 5.03307314011065e-08 106.644945120585 212.227797621086 0.502502246717891 0.615728465578855 ARHGEF26 other 0.00318961472134804 1 0.000604673407052894 5.61079109229239 0.502502246717891 4.52555120458848e-18 437.714761646727 45.2951077482249 9.66362115926042 4.30409091968167e-19 38.4837312611839 525.796061149466 0.0731913646843472 0.941709683249316 KLHL24 other 6.41994693882922e-14 1 6.55556087976716e-15 9.66362115926042 0.0731913646843472 0.0019177561500586 30.3324449192865 8.77915587125975 3.4550525544928 0.000640867130267815 67.6010652352478 59.4594865633211 1.13692648797524 0.256599909505746 PLCH1 other 1 1 1 3.4550525544928 1.13692648797524 0.437328907324569 -137.961832061068 118.287346173159 -1.1663279000199 0.244503504545439 -280.037433940105 310.923206261407 -0.900664306493307 0.36856357925076 VIPR1 other 1 1 1 -1.1663279000199 -0.900664306493307 0.34391533951776 9.18574236302395 27.6766431648795 0.331895104052224 0.740225007955077 -80.7505607633689 65.4180806580809 -1.23437679539126 0.218131830452098 DNAH1 other 1 1 1 0.331895104052224 -1.23437679539126 2.12233399206225e-08 689.978722382326 112.263371375811 6.14607163428726 2.94340064393466e-09 453.123208453412 762.359238071565 0.594369669605651 0.552777783200282 SSR3 other 0.000211957495787257 1 3.73753013766824e-05 6.14607163428726 0.594369669605651 0.492505706054698 -6.29083969465643 24.0967541381818 -0.261065853873176 0.794239277040656 -74.9828302994716 63.339319881 -1.183827525151 0.237514872658103 ZBTB47 other 1 1 1 -0.261065853873176 -1.183827525151 0.09280701232749 -5.02881171157159 69.9879457614841 -0.0718525405604784 0.942772258341802 -357.070207132849 170.663763055365 -2.09224384099049 0.0373471283303269 TNNC1 other 1 1 1 -0.0718525405604784 -2.09224384099049 0.00318120693800152 187.331297709923 105.880814531797 1.76926574033548 0.0779700648737844 -608.952618907815 278.312122140295 -2.18802046502612 0.0295190158219668 NKTR other 1 1 1 1.76926574033548 -2.18802046502612 1.2972091690015e-28 116.722351573987 9.10913672080348 12.8137665677381 1.15562817964418e-29 -27.0824851299595 99.0473975296181 -0.273429547927911 0.784732857133247 CLCN2 other 2.02066272255364e-24 1 1.82138557393718e-25 12.8137665677381 -0.273429547927911 0.0532749335714455 16.9807234329352 101.197213673084 0.167798329781996 0.866866628727668 -465.442979105822 216.615261995583 -2.148708151115 0.0325402859905902 FOXP1 other 1 1 1 0.167798329781996 -2.148708151115 3.3543250612377e-34 3418.47156961529 236.957499394938 14.4265177440859 2.45749898014034e-35 979.390999593398 2576.53654342389 0.380119196094114 0.704156892133192 EIF4G1 essential 5.29312494663309e-30 1 3.89661038291053e-31 14.4265177440859 0.380119196094114 4.35152669131336e-07 291.719271198317 79.9369035698875 3.64936916706152 0.000315115728454009 -534.675234758236 191.976629838627 -2.78510584964262 0.00572699817785389 SPCS1 other 0.00399296089194914 1 1 3.64936916706152 -2.78510584964262 2.51352429836002e-06 111.53889278206 23.5589344275387 4.73446255072043 3.53821612804048e-06 -28.2658374211638 56.579184732042 -0.499580146922058 0.617774605748871 NEK4 other 0.021636417160283 1 0.0376572342507348 4.73446255072043 -0.499580146922058 9.94217163636551e-05 -39.2083422294309 47.9119048362101 -0.818342379904684 0.41388603336425 -288.041051275231 71.1541682094299 -4.04812618183425 6.75535657850425e-05 SLC4A3 other 0.737311448552866 1 1 -0.818342379904684 -4.04812618183425 6.24578727410606e-12 91.9259161301273 19.0290785102672 4.83081280475713 2.2861465542757e-06 -137.408805428685 37.52100274991 -3.66218371999706 0.000301063722162232 INO80D other 7.45934374146487e-08 1 0.0246949550792861 4.83081280475713 -3.66218371999706 8.85988817669077e-05 620.484978384409 166.805269325049 3.71981641164637 0.000242672764391267 -268.237370750232 326.800851935485 -0.820797648358597 0.412488317380693 EEF1B2 essential 0.660947657981132 1 1 3.71981641164637 -0.820797648358597 0.31635369961325 467.279285697123 389.998899540207 1.19815539543323 0.231911098995537 1000.33342661202 764.076417605727 1.30920599505822 0.191581783590753 ADAM23 other 1 1 1 1.19815539543323 1.30920599505822 6.3050137231409e-07 229.196957590194 41.7734646053702 5.48666383684943 9.40050788172294e-08 68.9084304861269 183.303871686464 0.375924577326948 0.70726707589367 DGUOK other 0.0057054069180702 1 0.00111330214843245 5.48666383684943 0.375924577326948 1.64401915555164e-08 782.30035127923 129.601342421092 6.03620561843743 5.17204144954517e-09 958.357167625456 568.696613172355 1.68518177430223 0.0931046208516669 MOB1A other 0.000165273245707606 1 6.50177330622324e-05 6.03620561843743 1.68518177430223 1.31020735236769e-11 327.909629746711 45.4121531181505 7.22074614902261 5.47657152725874e-12 -121.034417354882 206.264220733524 -0.5867930798878 0.557842233630936 KANSL3 essential 1.54814100755766e-07 1 7.58012265087883e-08 7.22074614902261 -0.5867930798878 3.07392380976026e-09 171.605355253749 26.4652800452897 6.48416925723374 4.32024425942114e-10 174.498179933042 120.237235319673 1.45128237079892 0.147879557159473 LMAN2L other 3.2297717469151e-05 1 5.65476771115633e-06 6.48416925723374 1.45128237079892 0.0156031227149062 136.734459019224 55.7898132455172 2.45088576327526 0.0148850258482121 405.067555731992 240.370298631502 1.68518139736132 0.0931089561275156 RTKN other 1 1 1 2.45088576327526 1.68518139736132 1.24334195426138e-05 227.05386931277 51.9933899254394 4.36697567976188 1.79026970660426e-05 -154.242816912946 164.825386860447 -0.935795267045481 0.350205648352563 TTL other 0.100984233525109 1 0.180101132484389 4.36697567976188 -0.935795267045481 0.683137141290609 26.1215843507898 96.018511723002 0.272047377969639 0.78579197660237 -223.258889538378 304.245680868304 -0.73381120448845 0.463695849297273 IL1A other 1 1 1 0.272047377969639 -0.73381120448845 0.0184723368431474 -528.692165266583 262.85076653684 -2.01137768107853 0.0452682678511109 -1100.90789759414 396.198225814415 -2.77867952419814 0.00583685712203805 CCL20 other 1 1 1 -2.01137768107853 -2.77867952419814 8.6666522356896e-08 167.150953336678 55.2762826400807 3.02391813185131 0.00273631644821823 -295.205092824888 95.8509365818506 -3.07983524577041 0.00228564332058867 PIKFYVE other 0.00083286527984977 1 1 3.02391813185131 -3.07983524577041 0.304196535719127 12.8741606940778 8.52930745421139 1.50940281648789 0.132414811531087 21.3820098076199 37.9149862469828 0.563946131177124 0.573278780250306 KCNIP3 other 1 1 1 1.50940281648789 0.563946131177124 8.67756438367875e-16 125.262768766503 14.2091952855017 8.81561314695388 1.7770275685826e-16 1.36155865711063 63.1635624255147 0.0215560776629127 0.982818667733698 FAHD2A other 1.17095053793361e-11 1 2.64794877994493e-12 8.81561314695388 0.0215560776629127 2.30631333097356e-10 4115.60507863464 809.56423240734 5.08372889251342 6.88070663231333e-07 -1629.34622326625 1256.15076613547 -1.29709447877735 0.195693801834064 NCL essential 2.57868893536154e-06 1 0.00771327213482325 5.08372889251342 -1.29709447877735 3.29463289635001e-06 251.239494706488 51.6084489846392 4.86818533882441 1.92986042750059e-06 -207.641677214571 234.624301550405 -0.884996463889157 0.376954825047822 ACTR1B other 0.0280768615426948 1 0.0209853022886414 4.86818533882441 -0.884996463889157 1.19368071256152e-07 454.468873823676 80.1343511764483 5.67133653859602 3.64012318804297e-08 73.5388961119379 243.357993612232 0.302184017136151 0.762744431887189 SLC35F5 other 0.00113792520999974 1 0.000439763282347472 5.67133653859602 0.302184017136151 0.299584910449868 -26.8824444386663 18.0467123862675 -1.48960341713665 0.1375132536936 -53.6067813045342 78.6100781247221 -0.681932680686084 0.495874857734065 ZAP70 other 1 1 1 -1.48960341713665 -0.681932680686084 4.01351822685179e-10 2178.04836668834 325.94395987773 6.68227865767288 1.34124416929607e-10 367.417307067242 989.851005734265 0.371184455982539 0.710791234867244 ACTR3 other 4.43493764067123e-06 1 1.7866713579193e-06 6.68227865767288 0.371184455982539 0.0934294919080903 -69.9844917948275 105.094363809602 -0.665920504753397 0.50602419805042 -699.517591717501 319.871903140138 -2.1868678832071 0.0296008861059226 STEAP3 other 1 1 1 -0.665920504753397 -2.1868678832071 0.0473706902963385 107.732992702852 46.4003672673245 2.32181336156618 0.0209817879461906 -20.4536732854612 140.463734273995 -0.145615331894589 0.884332914569788 EPB41L5 other 1 1 1 2.32181336156618 -0.145615331894589 0.730213333502405 62.7413137319994 150.856099007209 0.415901737781255 0.677811060376946 -232.995162556224 449.557924704417 -0.518276177000813 0.60468847409995 TFCP2L1 other 1 1 1 0.415901737781255 -0.518276177000813 1.91896496956302e-13 436.851272782759 54.9361124751516 7.95198737406753 4.94197642704297e-14 446.135438191958 192.039290465749 2.32314667019418 0.0209089434890309 SF3B6 other 2.42499603203679e-09 1 7.12287062429704e-10 7.95198737406753 2.32314667019418 0.142298111718766 69.9782662213253 44.9746160333295 1.55595027580594 0.120882657444755 -164.770128007324 157.217046545052 -1.04804238235138 0.295549443639353 TP53I3 other 1 1 1 1.55595027580594 -1.04804238235138 4.75901523804028e-05 28.1613628371158 6.21635672178442 4.53020379902394 8.82957595691041e-06 1.90883850195807 21.6286249465198 0.0882551945247546 0.929738791892001 DNAJC27 other 0.365159239214831 1 0.0910517288945597 4.53020379902394 0.0882551945247546 0.498668716645421 32.0315224577096 27.8740076731113 1.14915382220436 0.251502040709849 -16.4105449596096 99.1911865693776 -0.16544357948709 0.86871775157969 POMC other 1 1 1 1.14915382220436 -0.16544357948709 3.69855372690837e-05 37.821949097237 27.3514398525359 1.3828138226416 0.167864516786521 -228.785888790349 63.5767985747183 -3.59857517080652 0.000380526081876556 STAM2 other 0.28697078367082 1 1 1.3828138226416 -3.59857517080652 0.751293215397538 4.50672105219344 10.8976456289283 0.413549972686774 0.679528388804479 -25.0968151169566 40.6680506126025 -0.617113796676043 0.537674008451224 OTOF other 1 1 1 0.413549972686774 -0.617113796676043 5.38294609893508e-08 475.773636597579 90.0377941976583 5.28415473565603 2.59237061190207e-07 -191.809424470549 241.860246466628 -0.793058914280961 0.428434716854341 GPD2 other 0.000524406608958255 1 0.00299211416025737 5.28415473565603 -0.793058914280961 2.3334442634389e-06 83.3924798135352 16.0693973786224 5.18952128998159 4.11953419225669e-07 43.6234862232581 59.9680966109837 0.727444903016449 0.467576838525447 CENPA essential 0.0201422908820045 1 0.00469008967788424 5.18952128998159 0.727444903016449 0.00845028176332474 -79.3032268359679 27.2773969259847 -2.90728719647082 0.00394620690741947 1.85319663068623 72.727850063192 0.0254812513923623 0.979689786953814 CYTIP other 1 1 1 -2.90728719647082 0.0254812513923623 0.000752530000817438 139.60604903514 55.1050520134737 2.53345281301985 0.0118565254947029 -265.851788950565 146.922815671703 -1.80946565538608 0.0714825184773457 ACVR1 other 1 1 1 2.53345281301985 -1.80946565538608 1.22983899156196e-09 297.00307663118 56.9766806411045 5.21271287286809 3.68609717495696e-07 -293.589542616222 149.156063039463 -1.96833797187678 0.0500446050221189 TANC1 other 1.32232288372742e-05 1 0.00420841714464836 5.21271287286809 -1.96833797187678 0.0731816975619862 36.0154555745323 17.9944906559759 2.0014712426757 0.0463311646074969 77.3929926123051 67.3060699316679 1.14986646361729 0.251205173269192 SLC30A3 other 1 1 1 2.0014712426757 1.14986646361729 2.78619723290634e-09 235.003079861249 36.2520735335643 6.48247277893413 4.20492205732333e-10 90.5616617680159 135.596202363624 0.667877567287318 0.504775967074776 MPV17 other 2.93720912292987e-05 1 5.50688238481978e-06 6.48247277893413 0.667877567287318 4.12833557983693e-10 367.259506858111 54.9104711049932 6.68833283465883 1.2722225510031e-10 311.462233222121 205.385530428789 1.51647602716643 0.130556073890696 GTF3C2 essential 4.55768248013996e-06 1 1.69574543823204e-06 6.68833283465883 1.51647602716643 4.6555694383212e-06 126.421864863434 25.0115065020254 5.05454818777895 7.91532573179807e-07 40.5683841733859 93.5523120885128 0.433643843403922 0.664889557340667 EIF2B4 essential 0.0392371392261711 1 0.00883746117955255 5.05454818777895 0.433643843403922 1.00379801173145e-06 516.327288629834 101.66787844985 5.07856853612348 7.05359867878515e-07 708.812034959157 380.275578096311 1.86394308703053 0.0634030595602443 NRBP1 essential 0.00893480610242165 1 0.00790003052023937 5.07856853612348 1.86394308703053 0.0179908032500201 31.699284068793 18.5544351343247 1.70844780987976 0.088689903747086 160.05487647456 69.4004699865579 2.30625061336849 0.0218458648363051 FNDC4 other 1 1 1 1.70844780987976 2.30625061336849 0.857368946336231 14.2900238725801 27.9428958951237 0.511400963100387 0.609485207359922 28.5971707262487 76.5660083034042 0.373496951975453 0.709069548661738 ITGA4 other 1 1 1 0.511400963100387 0.373496951975453 7.05959901776148e-09 543.503020416484 99.1028865377088 5.48422996952445 9.54502766126796e-08 -195.375352512636 240.873372719365 -0.811112288199087 0.418015606720916 PSMD14 essential 7.25938566996413e-05 1 0.0011299403745409 5.48422996952445 -0.811112288199087 1.91857026193025e-09 571.789119699197 89.120032146045 6.41594382239652 6.15396969246988e-10 -458.198382121249 333.341978420611 -1.37455949680329 0.170395287933703 SNX17 other 2.04289361490333e-05 1 8.00939155474955e-06 6.41594382239652 -1.37455949680329 5.7480386228276e-16 109.66816804257 12.4958827823731 8.7763441729199 1.9625976141901e-16 -68.8257591983023 59.5330643065581 -1.15609300478626 0.248665055252533 ASB3 other 7.7885923339314e-12 1 2.92387792562041e-12 8.7763441729199 -1.15609300478626 1.61292648521388e-09 794.690870304908 120.484656969951 6.59578481020287 2.18449129262804e-10 201.745103004065 450.657309659358 0.447668546986534 0.654747441210733 PPM1G other 1.72357324209956e-05 1 2.88789748885426e-06 6.59578481020287 0.447668546986534 0.202297943761616 -26.0419442784924 14.6802575604714 -1.7739432820725 0.0771953762909053 -32.1576632994386 38.0223182151513 -0.845757565792614 0.398434138713418 PDE1A other 1 1 1 -1.7739432820725 -0.845757565792614 0.566251460501937 -28.9189742628853 27.4600730850841 -1.05312808794357 0.293227333746059 -20.6793634648072 48.3092542470074 -0.428062154697579 0.668948385397029 REEP6 other 1 1 1 -1.05312808794357 -0.428062154697579 0.158379986508939 8.75010000698936 8.05106899557442 1.08682462065586 0.278087217164914 -10.4684632234521 14.1638785105299 -0.739095807385628 0.460493248113293 PCSK4 other 1 1 1 1.08682462065586 -0.739095807385628 4.19665911036049e-05 15.9122247720788 8.11656701929042 1.96046243864686 0.0509737237102763 -33.8555453846381 14.1608355591733 -2.3907872698025 0.0175002370699865 APC2 other 0.323856183546519 1 1 1.96046243864686 -2.3907872698025 0.692229603676411 9.3903900664516 61.3769999020777 0.152995260137075 0.878516713670134 -110.423400088117 152.589742571818 -0.723662011790505 0.469902082429293 IFIH1 other 1 1 1 0.152995260137075 -0.723662011790505 7.13554985303101e-16 1134.18391264443 239.480641862334 4.73601500240013 3.52510134191192e-06 -1566.36175183289 416.922124037791 -3.75696481794502 0.000210733562246796 RPS15 essential 9.64226851640081e-12 1 0.0375211786833105 4.73601500240013 -3.75696481794502 0.560649074282828 -4.10963787620243 30.5327759106708 -0.134597584190377 0.893030703960362 -78.9334353998336 75.9077247771204 -1.03986037826318 0.299338504379248 GCA other 1 1 1 -0.134597584190377 -1.03986037826318 2.40915932685879e-09 147.879313901274 22.6576810939498 6.52667469756038 3.33019106948559e-10 -8.27212854264074 97.2974650937291 -0.0850189522889624 0.93230956441515 INO80B other 2.54937239968197e-05 1 4.37520502709017e-06 6.52667469756038 -0.0850189522889624 4.5686952005448e-09 580.163718007712 93.4859872943165 6.20588961831485 2.04769090593074e-09 791.276318622907 401.451037632903 1.9710406611191 0.0497442150752738 MOGS other 4.74687431336605e-05 1 2.61469651778296e-05 6.20588961831485 1.9710406611191 9.03737694090503e-07 115.181711136754 21.2971326449271 5.40832012727264 1.40170318441838e-07 49.1554698039638 91.7586533464003 0.535703914685798 0.592604196832038 TTC31 other 0.00807399255900455 1 0.00164349698373055 5.40832012727264 0.535703914685798 1.76325913226154e-14 96.7367550967844 40.8740465261262 2.36670364983197 0.0186506015250742 -390.914686598847 71.1678445825771 -5.4928555008472 9.10864679385877e-08 NDUFS7 other 2.29611604203098e-10 0.00143980379870526 1 2.36670364983197 -5.4928555008472 3.74642976053773e-07 75.7932239047327 13.5565792028327 5.59088120762023 5.52596936810934e-08 24.6749696935035 58.408494344052 0.422455157774774 0.673029047600327 PCGF1 other 0.00345533216814395 1 0.000662508467542628 5.59088120762023 0.422455157774774 0.000991537105176026 27.7473634128936 7.93079609516634 3.49868576621268 0.000546352219720853 0.737984543408359 19.4155044096518 0.0380100628774544 0.969707643543759 GRB14 other 1 1 1 3.49868576621268 0.0380100628774544 0.000374910182959222 261.83987680015 66.7218452408549 3.92435005139548 0.000110133829068203 -233.926770344185 255.675231003463 -0.914937162376192 0.361032029949062 CLIP4 other 1 1 1 3.92435005139548 -0.914937162376192 0.00846378730800551 12.0408591008643 4.05927003391772 2.96626216050063 0.003284267075785 19.3428901127367 17.4893568111578 1.10598064420508 0.269719367511436 TLX2 other 1 1 1 2.96626216050063 1.10598064420508 0.809953690055728 313.623479890778 515.168128398023 0.608778887129581 0.543186668365804 657.613556617787 2454.57480438621 0.267913430644959 0.788972038918135 SPTBN1 other 1 1 1 0.608778887129581 0.267913430644959 2.06748132563723e-06 625.079504509809 119.824711259663 5.21661598795968 3.63350626506226e-07 407.426610057159 516.264528475239 0.789181877864963 0.430698155471129 AUP1 other 0.0179416029438799 1 0.00415055420658062 5.21661598795968 0.789181877864963 0.000109335107432442 763.419785711482 175.711287839142 4.34473957307949 1.98314048004274e-05 201.560209541502 835.309550989963 0.241300017822883 0.809507799940051 RTN4 other 0.806565087529123 1 0.198631350481081 4.34473957307949 0.241300017822883 1.64295672774499e-11 191.610672821045 25.968014156503 7.37871874477011 1.97619817210169e-12 10.3127529513089 111.883136984103 0.0921743278683211 0.926627886775683 HTRA2 other 1.93392436422863e-07 1 2.76470124277026e-08 7.37871874477011 0.0921743278683211 4.36732701104407e-05 58.5248217150668 12.89243162175 4.53947117441627 8.50091520287837e-06 40.2516496085573 56.1723302581558 0.716574324468462 0.474256150740021 LOXL3 other 0.336371526390614 1 0.0877804503849221 4.53947117441627 0.716574324468462 0.0845357789582309 22.8950863213812 11.5846670762505 1.9763266540752 0.0491354651691913 -47.3225194460255 50.4743995570323 -0.93755487655786 0.349311092081547 DOK1 other 1 1 1 1.9763266540752 -0.93755487655786 7.36337025339302e-09 523.897773509504 88.4866953354328 5.92063893361061 9.67739418618344e-09 35.9870242340093 213.289869452994 0.168723551316816 0.866139953780148 GALNT3 other 7.56291758725997e-05 1 0.000120251300157515 5.92063893361061 0.168723551316816 0.000568360525201827 149.077840987929 38.8581572430242 3.8364619314183 0.000155583983025521 -103.382581088492 169.293610689795 -0.610670306264096 0.541933478502065 POLE4 other 1 1 1 3.8364619314183 -0.610670306264096 0.00512277321594293 30.8066694417465 9.69517831506676 3.17752479022191 0.00165868867718391 -27.4906638387282 42.2390524845 -0.650835239469827 0.515708383932669 TACR1 other 1 1 1 3.17752479022191 -0.650835239469827 0.000111975837665129 125.405443735011 38.8700729125521 3.22627240800762 0.00141110270886495 599.414774816153 191.391563133524 3.13187668778258 0.0019308918804475 CCDC88A other 0.824925996079007 1 1 3.22627240800762 3.13187668778258 0.886683594571194 7.26252088816216 14.8315538856186 0.489666891559101 0.624771698261091 6.68767968929654 25.7235990681644 0.259982270427051 0.795077816252533 ACADL other 1 1 1 0.489666891559101 0.259982270427051 0.85982812662782 -8.89107811849596 31.1721055291395 -0.285225459351299 0.775690900167766 61.7776632506753 135.807734392209 0.454890610812068 0.649554832342193 EVA1A other 1 1 1 -0.285225459351299 0.454890610812068 5.1982665915003e-12 236.320311828087 31.8078133826133 7.42963085784652 1.4366995955804e-12 268.664655797324 134.578599018623 1.99634011467267 0.0469010098176111 MRPL19 essential 6.22752337661736e-08 1 2.01698256223532e-08 7.42963085784652 1.99634011467267 8.12409701539284e-07 353.144891023842 90.2481742235626 3.9130419430872 0.000115718049704811 -226.359087308686 156.524924378411 -1.44615362829657 0.149306944442049 LANCL1 other 0.00728325297429968 1 1 3.9130419430872 -1.44615362829657 1.91101231620167e-18 429.469897047797 47.024318375689 9.1329318931676 1.6812718284505e-17 -89.8327340001403 119.813080674044 -0.749774010439925 0.454048490052802 WDR75 essential 2.73026329615733e-14 1 2.52913721153809e-13 9.1329318931676 -0.749774010439925 4.84092716366912e-05 911.793459178033 279.964214294866 3.25682145296508 0.0012729120685675 4683.69432248434 1378.51011280301 3.39764959210977 0.000783719367093673 EFEMP1 other 0.371153885638511 1 1 3.25682145296508 3.39764959210977 1.99732564546047e-05 172.179016522404 36.4238653545877 4.72709348242519 3.72882404119535e-06 -88.8118641964612 215.364050696595 -0.412380171663744 0.680399308349267 FANCL other 0.159366613251291 1 0.0396224842617418 4.72709348242519 -0.412380171663744 0.456068421464665 -3139.26843816124 7452.48698114145 -0.42123769502787 0.673912974241144 -13696.9036096689 11209.9060146323 -1.22185713170033 0.222815643138337 FN1 other 1 1 1 -0.42123769502787 -1.22185713170033 0.451581807832117 615.810186172567 537.25547587545 1.14621481552908 0.252744140742319 -302.511295717356 1372.29050328723 -0.220442606716807 0.825696843915286 STAT1 other 1 1 1 1.14621481552908 -0.220442606716807 0.334928658689192 126.585239196403 120.362513654639 1.05169986362713 0.293888170616179 -211.397972267574 302.1440274554 -0.699659609517779 0.484749015861724 GLS other 1 1 1 1.05169986362713 -0.699659609517779 1.68918552956247e-17 135.790324743507 14.4324975798397 9.40865044267792 2.77574425100091e-18 125.989870161634 91.9590501408693 1.37006493617141 0.171848530831161 PAPOLG other 2.37110972784684e-13 1 4.20275437044048e-14 9.40865044267792 1.37006493617141 0.657128986889745 -11.6487571930947 13.2181070342131 -0.881272724070371 0.378965818659071 7.96735800298378 54.398585736348 0.146462594479918 0.883667153767376 DNAH6 other 1 1 1 -0.881272724070371 0.146462594479918 0.00288141438144233 43.141494679383 14.4844359791196 2.97847253020931 0.00315727809300136 2.98830195533567 21.7872458431345 0.137158316239284 0.891006757148973 PECR other 1 1 1 2.97847253020931 0.137158316239284 1.38503218337669e-07 142.280642281779 24.7701704984253 5.74403160813223 2.47861455788159e-08 25.8327665724426 106.294563293101 0.243029989231059 0.808166012910611 UNC50 essential 0.00131425703880615 1 0.000301854897005175 5.74403160813223 0.243029989231059 0.251782017081007 2543.40585892354 3092.01426549811 0.822572485290203 0.411469039977606 -3594.07517540216 4636.93686148541 -0.775096854402891 0.438953272077651 IGFBP2 other 1 1 1 0.822572485290203 -0.775096854402891 0.00049157396511505 40.7039194915256 13.3323125306768 3.05302770227358 0.00249415225619884 -117.525529661017 54.9130171839675 -2.1402125704965 0.0332438248358223 ELMOD3 other 1 1 1 3.05302770227358 -2.1402125704965 0.446624021849701 854.427627602066 3760.69873331915 0.227199169141623 0.820438919693583 -5249.47175466052 5639.7290193808 -0.930802124822102 0.352778295794286 IGFBP5 other 1 1 1 0.227199169141623 -0.930802124822102 1.83566138497846e-14 656.917034207567 80.2283450418911 8.18809155124112 1.21625236700726e-14 1165.47807068152 506.948955502124 2.29900477756609 0.0223010694419011 USP34 other 2.38892972641097e-10 1 1.77025532017906e-10 8.18809155124112 2.29900477756609 0.831586395492288 -29.0071128456621 115.563510094616 -0.251005813356768 0.801998433610839 -106.390789841098 176.703281515183 -0.602087233065656 0.547615791196629 EFHD1 other 1 1 1 -0.251005813356768 -0.602087233065656 2.59522069017608e-18 2012.03652998152 209.598769769927 9.5994672687731 6.97145812653664e-19 2446.02790264611 1322.41780187464 1.84966347184578 0.0654924862389647 CCT4 essential 3.6979299614319e-14 1 1.06007992272116e-14 9.5994672687731 1.84966347184578 0.00549867480465785 163.909759276754 51.2705159799723 3.19695942480434 0.00155731628061621 -58.1459682144865 217.187380498186 -0.267722590884934 0.789121117130086 GGCX other 1 1 1 3.19695942480434 -0.267722590884934 3.28034514357869e-05 264.781784182806 57.4733369751686 4.60703689951402 6.39197888337984e-06 207.880485456076 355.717071577779 0.584398394302596 0.559457090845567 EHBP1 other 0.25593252810201 1 0.0666939076691853 4.60703689951402 0.584398394302596 1.78353281282328e-06 153.454268381692 29.106566557644 5.27215286893369 2.82196722432151e-07 -30.8776526709621 180.316691704762 -0.171241233293693 0.864166264750035 OTX1 other 0.0155755920543857 1 0.00324695548830433 5.27215286893369 -0.171241233293693 6.47413334885771e-06 136.899186664519 27.6714721059453 4.94730407332055 1.32005810932186e-06 177.460444516025 117.874057733716 1.50550891288495 0.133353650634652 TXNDC9 other 0.0538065222623565 1 0.0145113987957752 4.94730407332055 1.50550891288495 1.82196095935915e-09 180.982956329475 29.3859659987421 6.15882276380578 2.65862392133512e-09 -42.8860727664238 73.23389624071 -0.585604139174339 0.558632527321175 COQ10B other 1.94166379438905e-05 1 3.38044031597761e-05 6.15882276380578 -0.585604139174339 0.944942419036531 -5.1117589527535 37.144688429815 -0.137617494420829 0.890646450567207 -50.6650511115706 158.051368294738 -0.320560661120562 0.748794093910744 GNLY other 1 1 1 -0.137617494420829 -0.320560661120562 3.11463126204309e-12 1377.0525496411 210.184076285829 6.55165022001217 2.88341568671254e-10 -1064.80407912839 523.807821557568 -2.03281439357309 0.0430532546848528 SF3B1 essential 3.76465480643148e-08 1 3.7945750437137e-06 6.55165022001217 -2.03281439357309 0.282699975862558 -6.65046644598253 35.6700612166243 -0.186443931385322 0.852238223305529 -241.82789930033 151.776800957612 -1.5933126655362 0.11227316427221 ST3GAL5 other 1 1 1 -0.186443931385322 -1.5933126655362 0.00124277345077574 121.048645508615 33.6906618129519 3.59294353375036 0.000388221876722204 -27.9962707261565 133.665511110209 -0.209450220132501 0.834254155511755 CHST10 other 1 1 1 3.59294353375036 -0.209450220132501 5.88005320527377e-12 108.303327420681 14.6470641238222 7.39420040119405 1.77906346919025e-12 -6.23577616707156 58.1112749652795 -0.107307509098662 0.914624425602189 PDCL3 other 7.02842759626374e-08 1 2.49246792033554e-08 7.39420040119405 -0.107307509098662 2.08765445662274e-11 276.325102308378 40.3891837570754 6.8415619382249 5.2711813240382e-11 -72.7537929972877 100.655438471522 -0.722800417961235 0.470430461616985 MOB4 other 2.4458959613792e-07 1 7.1060795429359e-07 6.8415619382249 -0.722800417961235 5.07363061298012e-08 574.778956179042 101.379956975068 5.6695521810134 3.68612674125537e-08 -75.812359131925 252.652890509626 -0.300065275243849 0.764359114099949 HSPE1 essential 0.000494881929990081 1 0.000445099804006586 5.6695521810134 -0.300065275243849 2.07747649884728e-05 523.277193445218 111.883175723235 4.67699625133674 4.62821927758014e-06 -56.8916130875838 462.736978652841 -0.122945897371789 0.902242433613607 KDM3A other 0.165491777898174 1 0.0488092005013601 4.67699625133674 -0.122945897371789 0.000724744405110002 9.22576488119712 9.63881435672935 0.957147273487651 0.339349163769043 -37.479098305181 14.3461766445113 -2.61247991251524 0.00949230982333668 PLCD4 other 1 1 1 0.957147273487651 -2.61247991251524 6.97293864043283e-05 336.156286062845 78.7878246278495 4.26660194834243 2.75847188368504e-05 -225.030004286327 325.858107684637 -0.690576661987214 0.490431503005892 CHMP3 essential 0.526038491034253 1 0.273226640079004 4.26660194834243 -0.690576661987214 6.19551747953401e-09 73.9537928378902 34.3451548706481 2.15325256550502 0.0321844694133868 -197.306507508663 51.1184924226101 -3.859787293363 0.000142050838149447 ZNF142 other 6.39739118062081e-05 1 1 2.15325256550502 -3.859787293363 0.0490567607040574 171.139795262173 72.5844051560708 2.3578039235038 0.0190916512434092 -80.3681319881722 271.42238106376 -0.296099870884608 0.767379753972153 IL1R2 other 1 1 1 2.3578039235038 -0.296099870884608 0.102215409655852 -342.199974163179 159.563448939195 -2.14460126324784 0.032870767059479 -217.70616502701 596.672124662299 -0.3648673300269 0.715493968996662 IL1R1 other 1 1 1 -2.14460126324784 -0.3648673300269 0.0645789046383688 5.01682730313641 14.4063181939458 0.348237990831322 0.727932819308941 -37.7724004947748 21.3746026279883 -1.76716270015307 0.0783306219923851 WNT6 other 1 1 1 0.348237990831322 -1.76716270015307 0.0575927629933734 15.5790972499932 6.72336663377062 2.31715717714119 0.0212379226731242 -5.13290005993762 25.1413809423501 -0.204161421033614 0.838380030922845 IL1RL2 other 1 1 1 2.31715717714119 -0.204161421033614 0.657428955383704 -65.5860475454546 76.1879856518411 -0.860845013611011 0.390081591568883 43.9861905978661 284.897622700221 0.154392971696186 0.877414390783957 IL1RL1 other 1 1 1 -0.860845013611011 0.154392971696186 0.841800661824872 7.94651112645699 13.6455596746576 0.582351425366243 0.560812396155806 9.08304543956316 51.0262540538768 0.178007294636457 0.858849745467754 IL18R1 other 1 1 1 0.582351425366243 0.178007294636457 0.215486420941552 -6.03974041306954 3.48417134844195 -1.73347973134857 0.084147825788192 -0.414911156239325 13.0212083367178 -0.0318642591002356 0.974603756154999 IL18RAP other 1 1 1 -1.73347973134857 -0.0318642591002356 0.339902972913253 64.4284974215495 58.7776709856493 1.09613899872419 0.273987504090694 -169.164308394944 220.580323512553 -0.766905704466958 0.443802707646045 SLC9A2 other 1 1 1 1.09613899872419 -0.766905704466958 0.971661916366871 -27.5175119236873 119.377074491017 -0.230509183115874 0.817869403857259 -49.1113294912555 419.436469824904 -0.117088839489225 0.906876063068677 FHL2 other 1 1 1 -0.230509183115874 -0.117088839489225 0.0920640610051982 -132.977916268755 159.128938415739 -0.835661430238021 0.404076171688646 -548.050358918687 252.546538631899 -2.17009649741231 0.0308618665322271 MLPH other 1 1 1 -0.835661430238021 -2.17009649741231 1.72604046578379e-18 95.4976758605093 59.1536943937369 1.6143991823209 0.107608869463926 -634.416494353181 87.7661241839666 -7.22848935454162 5.02206570072738e-12 CNPPD1 other 2.46806526202424e-14 8.01371023865067e-08 1 1.6143991823209 -7.22848935454162 3.19021764432633e-08 361.39701654101 60.5480984919726 5.96875914425163 7.43437103897198e-09 63.2247564426374 217.475626514911 0.290721114158062 0.771486164956235 UXS1 essential 0.000315257307612328 1 9.27883849374093e-05 5.96875914425163 0.290721114158062 0.278188089216724 293.143474149875 199.498601444852 1.46940114881411 0.142888219446803 75.9515920525996 295.995359349701 0.256597239292753 0.797685118559746 ABCB6 other 1 1 1 1.46940114881411 0.256597239292753 1.24083631576934e-18 114.49963511909 31.4095314049449 3.64537864773952 0.000320227756964241 -265.149021455742 46.6022090775529 -5.68962344713091 3.30860282323189e-08 STK16 other 1.77675352055012e-14 0.000524512805566951 1 3.64537864773952 -5.68962344713091 0.575287439596113 -17.8763080573552 23.3824291486081 -0.764518859171625 0.445223287160395 -72.5692795373025 81.6324298517088 -0.888976105074047 0.374804322626293 SLC5A7 other 1 1 1 -0.764518859171625 -0.888976105074047 1.18389232104406e-11 2057.57330681971 646.696575645037 3.18166723670589 0.00163600513941881 -4334.30619441875 1044.92615416986 -4.14795454886678 4.50246263837374e-05 HDLBP other 1.40042622656302e-07 0.680817375548493 1 3.18166723670589 -4.14795454886678 3.54654406803222e-16 138.273406635761 38.5679220595209 3.58519202622238 0.000399638635620589 -318.388612479562 60.7653782148857 -5.2396384558595 3.24518917616921e-07 PPP1R7 essential 4.8318116382871e-12 0.00510695420653748 1 3.58519202622238 -5.2396384558595 5.55750881096057e-05 71.7331777351904 35.4262464944719 2.02485966856195 0.0438658334070147 -134.183582356639 55.8155366433318 -2.40405432655944 0.0168884568759345 PASK other 0.423760046835744 1 1 2.02485966856195 -2.40405432655944 1.26727725585858e-22 365.363993596275 82.4458132157007 4.43156516196139 1.365002144225e-05 -862.592344636878 133.183827530392 -6.47670487199385 4.46105133793053e-10 STK25 other 1.90674535916483e-18 7.1082392018585e-06 0.138615967746048 4.43156516196139 -6.47670487199385 0.411290595348883 9.61490560008085 9.72831998251938 0.988341832645069 0.323890221991704 -15.2067641539053 28.8873633600272 -0.526415788259428 0.599041324124909 TPO other 1 1 1 0.988341832645069 -0.526415788259428 0.160376415238489 4.61739672012273 7.25913768785549 0.636080608836999 0.525260709189571 -29.4747606447999 19.6436215551894 -1.50047487740433 0.134655570402254 PROC other 1 1 1 0.636080608836999 -1.50047487740433 0.905789867316212 27.2614291934252 66.152557784124 0.4120993973111 0.680593557177322 -4.95732712373116 199.007521171391 -0.0249102500978431 0.98014495176231 ID2 other 1 1 1 0.4120993973111 -0.0249102500978431 2.30532087786977e-12 102.628622598971 13.4858200169032 7.6101136208503 4.54739896180058e-13 55.6617151215525 40.7156584681368 1.3670837514543 0.17273195796562 TAF1B essential 2.80257859122628e-08 1 6.45867074544537e-09 7.6101136208503 1.3670837514543 0.0205967869688603 131.206073552323 68.4087620696488 1.91797175658198 0.0561654293424158 -298.37529205759 212.027492201203 -1.40724813070207 0.160499702515643 HPCAL1 other 1 1 1 1.91797175658198 -1.40724813070207 0.226918528648574 849.229951952568 874.634663865341 0.970953916003626 0.332437027947485 -2945.63669852182 2710.86025767872 -1.08660588098486 0.278176569115833 ODC1 other 1 1 1 0.970953916003626 -1.08660588098486 2.46780180761872e-07 358.983269084225 68.5853822921389 5.23410757638032 3.33462654327066e-07 643.706883993006 269.640374622718 2.38727929707739 0.0176619603643298 BIRC6 other 0.00230393976759283 1 0.00381914778000789 5.23410757638032 2.38727929707739 1.99906194395339e-16 258.652721597885 29.8185399423608 8.67422489826333 3.91123268354817e-16 -12.4474971014809 92.4201820615202 -0.134683754390304 0.892961893071579 NOL10 essential 2.73871486321615e-12 1 5.8058337954589e-12 8.67422489826333 -0.134683754390304 4.05482168290177e-06 357.897453775655 104.111025858566 3.43765178398928 0.000678671294202088 -596.918221606515 265.858703217393 -2.2452461190199 0.0255557979896554 PLEKHB2 other 0.0343402848324951 1 1 3.43765178398928 -2.2452461190199 5.73115008870745e-16 644.944495431431 85.2196724019277 7.56802364118032 5.89125876819942e-13 -402.716527650972 233.439954722008 -1.72513967512779 0.0856381596285493 GORASP2 other 7.76628148520747e-12 1 8.34025503813992e-09 7.56802364118032 -1.72513967512779 2.2767961208488e-08 215.110773828982 35.6084681574895 6.04100049678038 5.01812172000461e-09 188.312990550912 131.519966482898 1.43182054852028 0.153343263980647 STRN other 0.000226905501403792 1 6.3107898750778e-05 6.04100049678038 1.43182054852028 9.67255875434192e-13 389.88097605693 49.8097662203146 7.82740023979311 1.11343917218318e-13 147.480584515468 184.13372637897 0.800942811595169 0.423863818543265 CEBPZ essential 1.19281994558545e-08 1 1.59656042899347e-09 7.82740023979311 0.800942811595169 0.000338020601754951 151.938712885133 41.9805639800013 3.61926326091077 0.000352218543631972 320.133498547257 155.191205815693 2.06283272859837 0.0400777062941459 PRKD3 other 1 1 1 3.61926326091077 2.06283272859837 6.99374752747378e-15 144.401515991188 17.6864200475957 8.16454181245222 1.22889268952704e-14 21.437473836557 51.5913830976757 0.415524309475682 0.678086940627901 DCAF17 other 9.21216424318847e-11 1 1.78853042033766e-10 8.16454181245222 0.415524309475682 0.953530091879653 -13.9369183201008 53.0584110448401 -0.262671234318015 0.793002831319066 28.3698683985644 196.14311976933 0.144638610989405 0.885103323315447 QPCT other 1 1 1 -0.262671234318015 0.144638610989405 9.88995310468886e-13 328.14014432655 54.6823340643104 6.00084378147855 6.32081536041788e-09 -326.514417897672 133.046115189846 -2.45414469585799 0.0147561544607955 RAB3GAP1 other 1.21923341874604e-08 1 7.91429291277923e-05 6.00084378147855 -2.45414469585799 8.24662955134272e-08 105.578660144379 22.7524279409714 4.64032499820639 5.43084423510326e-06 -124.645282647717 67.398532422636 -1.84937680639845 0.0654962825810491 SLC25A12 other 0.000793903026907764 1 0.0570021410916438 4.64032499820639 -1.84937680639845 0.497319232946361 4.57343669733339 7.78970486669219 0.587112961992801 0.557614853105375 -28.3989554631922 28.7712944698393 -0.98705866338279 0.324491092775653 RMDN2 other 1 1 1 0.587112961992801 -0.98705866338279 0.664410030722223 14.7665124325075 31.3396087710969 0.471177306020679 0.637894595572298 -52.7910939536256 92.835966489004 -0.568649155603701 0.570066926395337 DLX2 other 1 1 1 0.471177306020679 -0.568649155603701 4.95801666845042e-15 831.423051175689 104.881187362295 7.92728488383404 5.99561012800182e-14 -63.0469230033602 253.649249566267 -0.248559469863083 0.803891218504009 DARS essential 6.56441406902835e-11 1 8.62828253520742e-10 7.92728488383404 -0.248559469863083 3.97526333498772e-05 373.097711860426 82.0830035848703 4.54537109469512 8.25882069496462e-06 -97.2434840488008 302.239820501045 -0.321742793148809 0.747894673473684 SRSF7 essential 0.30743703774352 1 0.0853962059859341 4.54537109469512 -0.321742793148809 0.0182389866809499 1432.61808136417 1449.69463298204 0.988220587129619 0.323929383913775 -11390.3475655771 4743.1731598689 -2.40141929920431 0.0170079441524292 SDC1 other 1 1 1 0.988220587129619 -2.40141929920431 0.541003536506353 14.2133891859439 13.0554109111847 1.08869719096832 0.277269134109569 2.83404344986758 32.0968137744089 0.088296722216309 0.929707033378831 PLCL1 other 1 1 1 1.08869719096832 0.088296722216309 0.0300075076020739 418.164661294478 179.557210367771 2.32886588312432 0.0206184559459851 -1272.2909445487 1057.50803359348 -1.20310286459515 0.230010257644059 SLC1A4 other 1 1 1 2.32886588312432 -1.20310286459515 2.48231557415288e-05 259.609606740693 55.4272673485436 4.68378866863829 4.45226667834214e-06 -8.44556389093357 204.090086895591 -0.0413815488022904 0.967022081180904 SOS1 other 0.196201660384838 1 0.0470203883899714 4.68378866863829 -0.0413815488022904 0.263561397129285 122.473723443906 148.091962812114 0.827011278115681 0.408969150166691 -348.482758648152 349.43255323569 -0.997281894377776 0.319530645054019 KYNU other 1 1 1 0.827011278115681 -0.997281894377776 0.00204535505136615 -224.290654485514 71.8879618512214 -3.12000297003418 0.00200450555649747 133.128461746985 208.432895680648 0.638711376686716 0.523552133432088 WIPF1 other 1 1 1 -3.12000297003418 0.638711376686716 3.22653158987211e-21 284.195488581753 29.0907986431657 9.76925701036123 1.96409631789142e-19 -41.4693526555653 65.0297266509047 -0.637698400274428 0.524224818725874 ORC2 other 4.79043145148312e-17 1 2.99701457147052e-15 9.76925701036123 -0.637698400274428 4.56719502218183e-12 859.198677089598 113.573525293882 7.56513170535424 5.94767105366844e-13 169.671176588494 457.25280986971 0.371066449294954 0.710875826437732 COX7A2L other 5.47789370960489e-08 1 8.41892837646767e-09 7.56513170535424 0.371066449294954 1.48707170072271e-15 324.281020147106 37.5136106793532 8.64435638890884 4.94021856536071e-16 409.32695075152 193.528432955646 2.11507396871927 0.0353431530999634 PNO1 essential 1.99490668651952e-11 1 7.32436804500379e-12 8.64435638890884 2.11507396871927 1.89568383811745e-07 164.138157383311 34.3953937101986 4.7720970652719 3.00018471758114e-06 -93.1371411006805 79.8301143704522 -1.16669181592897 0.244371945335702 ORC4 essential 0.00178326978651708 1 0.0321349785100116 4.7720970652719 -1.16669181592897 0.719443662065128 -50.1103117280765 64.0712094093418 -0.782103415715613 0.43483913318569 -83.3299636103313 331.175111255541 -0.251619040133823 0.801526948465499 PLEK other 1 1 1 -0.782103415715613 -0.251619040133823 0.0128617582773993 386.711812627292 146.13745562438 2.646219690736 0.00861919992220452 -106.876512263477 341.226789649139 -0.313212548092637 0.754361896110821 RND3 other 1 1 1 2.646219690736 -0.313212548092637 2.19422155393392e-08 178.879566838933 32.5333381491977 5.49834652744801 8.882865839594e-08 -80.0222679853446 94.32758562037 -0.848344282948167 0.396997719979534 ATF2 other 0.000218917484435988 1 0.00105297491662547 5.49834652744801 -0.848344282948167 2.86730471760268e-15 204.832858988636 23.5225540957539 8.70793444261272 3.05692367063027e-16 70.969536769757 94.3555261725805 0.752150294196342 0.452611058904582 THADA other 3.81752950101621e-11 1 4.54228288218951e-12 8.70793444261272 0.752150294196342 1.00962078323575e-05 206.604246519409 48.8116219771621 4.23268553985103 3.16428218783604e-05 623.024049434846 229.255362465331 2.71759858846949 0.00699949209283888 AAK1 other 0.0826677497313432 1 0.311460295748701 4.23268553985103 2.71759858846949 0.0110984829920201 109.284673123486 57.5696676234484 1.89830300633826 0.0587344722846138 -185.14627118644 123.507225645692 -1.49907238397187 0.135036263487477 TRAK2 other 1 1 1 1.89830300633826 -1.49907238397187 3.1323216970565e-08 44.2362951467644 7.28815398427881 6.06961587833983 4.27317073558453e-09 11.6152882704154 33.970936117796 0.341918404312993 0.732675357182973 C2orf42 other 0.000309849262272829 1 5.38932293171921e-05 6.06961587833983 0.341918404312993 0.00222713115553219 276.551908881121 78.6946799561302 3.51423894264886 0.000516075601246971 -63.7559585662039 363.624541054133 -0.175334586552871 0.860946710205004 TIA1 other 1 1 1 3.51423894264886 -0.175334586552871 0.000172972624909575 446.445958893941 107.786514664203 4.14194633052933 4.59578936308122e-05 542.583096044588 498.049194029947 1.08941667318904 0.276930890554868 PCYOX1 other 1 1 0.44528603138894 4.14194633052933 1.08941667318904 0.721178025342367 -673.851665937227 1120.58771217311 -0.601337725389167 0.548119599856747 -2756.97577196454 4503.54066027445 -0.612179611540695 0.540934117455098 EPAS1 other 1 1 1 -0.601337725389167 -0.612179611540695 2.09805882336487e-06 150.81260478498 35.3289228759489 4.26881411908682 2.7202737743503e-05 -14.1490242566234 62.1807242956999 -0.227546790695744 0.820170164202497 ARID3A other 0.0181943661162202 1 0.269524725562627 4.26881411908682 -0.227546790695744 2.47256976611937e-11 440.231649070922 71.1592479259412 6.18656972778987 2.28996027379173e-09 -315.271822713192 162.200650444666 -1.9437149101985 0.0529764718953633 SUMO1 other 2.8874669728742e-07 1 2.91878336497494e-05 6.18656972778987 -1.9437149101985 0.0830005792905091 -23.3048821501639 11.2741960372923 -2.06709924797094 0.0396673341173656 -50.0893432679255 51.1186798826255 -0.97986378722879 0.32802089292022 CD207 other 1 1 1 -2.06709924797094 -0.97986378722879 0.433551511345169 -8.28945605510894 7.10195461889013 -1.1672076913953 0.244152491262642 -13.8157177290981 12.4998059994185 -1.10527457224063 0.270020924250024 GRIN3B other 1 1 1 -1.1672076913953 -1.10527457224063 0.0325131127814261 11.7382080098652 4.48500426940257 2.61721222651785 0.00935942058866396 -3.10520605204049 20.335596149068 -0.152698058580535 0.878749188121097 VAX2 other 1 1 1 2.61721222651785 -0.152698058580535 0.224963563273377 90.8709116896945 53.4426983160767 1.70034288224475 0.0902052889768281 -56.9245576877649 242.316186293615 -0.234918511051463 0.814448087085916 ATP6V1B1 other 1 1 1 1.70034288224475 -0.234918511051463 3.41145998826142e-07 2078.60926919581 443.798527817975 4.68367770261815 4.52124582892776e-06 -1946.42097526272 1320.17078463101 -1.47437058744392 0.141577829290204 NFE2L2 other 0.00315867080313125 1 0.0477217497243325 4.68367770261815 -1.47437058744392 8.29551217796205e-22 1079.75114931961 100.554844763957 10.7379326362068 1.28068836088784e-22 -49.3822198820794 480.518487263747 -0.102768615965809 0.918223183248497 MSH6 ts 1.23901769890041e-17 1 1.98378627101526e-18 10.7379326362068 -0.102768615965809 9.73335239845671e-11 90.1323166971451 14.2644572912105 6.31866427562464 1.10520402496434e-09 -41.3515119378112 40.3273350045693 -1.02539659347998 0.306107667264424 PLEKHA3 other 1.10823950408828e-06 1 1.42637631461897e-05 6.31866427562464 -1.02539659347998 2.01812799020987e-06 244.687394617927 48.47172509162 5.04804386795447 8.18280105840989e-07 359.253140720329 212.887163818694 1.68752842715444 0.0926481014599995 SPR other 0.0175375322349238 1 0.00912709630055039 5.04804386795447 1.68752842715444 0.00641248470265053 -124.654223191081 87.0505630113701 -1.43197492214725 0.153299114133762 -411.106655216516 128.915243625869 -3.18896853198841 0.00159479966788343 EPHA4 other 1 1 1 -1.43197492214725 -3.18896853198841 0.383143529959617 14.0995955769426 33.1947093509746 0.424754301291348 0.671355332647253 -74.8846031655215 68.5717938852828 -1.09206131154742 0.275783254792823 PARD3B other 1 1 1 0.424754301291348 -1.09206131154742 1.05498056723237e-10 253.288738687902 70.6452959531162 3.58535887309464 0.000398907752062045 -334.502159173054 104.023540320282 -3.21563905768965 0.0014587153785472 FARSB essential 1.19835242631925e-06 1 1 3.58535887309464 -3.21563905768965 1.96875426619407e-05 200.678434292686 42.3059052656588 4.74350880881833 3.40104032723122e-06 111.249742816813 181.090920042093 0.614330871978308 0.53951210537908 ALMS1 other 0.157214997746318 1 0.0362380846866486 4.74350880881833 0.614330871978308 0.0338775194942884 102.420563892905 39.8513404340277 2.5700657186791 0.0107411958184901 -59.7956050256769 135.105127784677 -0.442585755301425 0.658443533275363 BCL9 og 1 1 1 2.5700657186791 -0.442585755301425 0.214292711390833 -206.412436939784 206.397172265322 -1.00007395776936 0.318170141685036 -1042.61685303186 693.602094901784 -1.50319161475355 0.133958363046883 PRRX1 other 1 1 1 -1.00007395776936 -1.50319161475355 0.00133189124943212 1360.32686327649 990.972153706489 1.37271956450898 0.170974449980408 -3796.14061779993 1754.52806224705 -2.1636249083062 0.0313671215832443 DHCR24 other 1 1 1 1.37271956450898 -2.1636249083062 7.07373291445486e-17 138.800219168378 26.3530653377738 5.26694778726272 2.81578052726875e-07 -145.94930439868 40.8527910722262 -3.57256629395643 0.000417740152249118 DNAJC16 other 9.80207169956009e-13 1 0.00324011865272815 5.26694778726272 -3.57256629395643 0.0134147181492793 102.583077645323 46.0860223436406 2.22590435079018 0.0268402029462972 -215.069656120584 128.034125962763 -1.67978384281027 0.0941475384451743 MARK1 other 1 1 1 2.22590435079018 -1.67978384281027 0.451389239405048 -13.8458025270004 11.4928998891009 -1.20472662779659 0.229375614389368 9.15699470606993 36.686582805 0.249600644321169 0.803088119977699 TNR other 1 1 1 -1.20472662779659 0.249600644321169 1.57046712315407e-10 43.1550003221887 9.34536599193873 4.61779670902285 6.03467915392608e-06 -30.6836914608785 14.8945351627041 -2.06006371636964 0.0403615423793555 MORN1 other 1.76913121423306e-06 1 0.0630563624793736 4.61779670902285 -2.06006371636964 4.72053810657891e-06 150.065937305833 41.725876986309 3.59647173755202 0.000383234583086769 -84.0959966374677 73.9427290574492 -1.13731258920847 0.256412207971369 GPX7 other 0.0397445872780251 1 1 3.59647173755202 -1.13731258920847 9.39097019618396e-14 542.071958635559 66.2714876168089 8.17956527202008 1.16595258184592e-14 25.3408798316951 211.656546130687 0.11972641666395 0.904789910392141 CACYBP other 1.19828779703307e-09 1 1.69751036390948e-10 8.17956527202008 0.11972641666395 2.98973112044976e-09 252.976858809078 84.1574310133012 3.00599549871115 0.00289531472107408 -490.729027650297 147.719544333117 -3.32203182636193 0.00101651760563726 SCP2 other 3.14459919248906e-05 1 1 3.00599549871115 -3.32203182636193 0.182794896056487 15.0062242142065 8.86013810882344 1.69367836368854 0.0914882728102833 25.8018623763526 28.2729708699926 0.91259820183019 0.362274102690648 PAPPA2 other 1 1 1 1.69367836368854 0.91259820183019 1.13395097997337e-08 236.185412272526 37.7374894495848 6.25864135949099 1.54731019960815e-09 47.8796681646047 117.33655075416 0.408054164340663 0.683562165594156 RALGPS2 other 0.000115107363977096 1 1.98550844813717e-05 6.25864135949099 0.408054164340663 0.450031407812772 -5.29307892284298 7.52284131706701 -0.703601033140845 0.482296686724142 22.7874462484263 23.3906458773515 0.974211929329011 0.330836418188829 ANGPTL1 other 1 1 1 -0.703601033140845 0.974211929329011 1.03733621089866e-14 202.178106710609 37.9074698241036 5.33346350069645 2.05018080359335e-07 -152.198379218256 59.7794225350957 -2.54599948885257 0.0114568079122075 CEP104 other 1.3603627069725e-10 1 0.0023796448587308 5.33346350069645 -2.54599948885257 3.31503277149327e-11 726.024737986625 100.016882181864 7.25902189858776 4.2924925646471e-12 86.0128987007387 310.980834803103 0.276585850556345 0.782312920299966 FAM20B other 3.85041056408943e-07 1 5.95970359979754e-08 7.25902189858776 0.276585850556345 1.0283422169591e-10 226.769637992466 240.966489701101 0.941083709497343 0.347496991310445 -2326.91448756642 426.855702127867 -5.45129062577072 1.12195515877777e-07 TMEM59 other 1.16932793490419e-06 0.00177212817328948 1 0.941083709497343 -5.45129062577072 2.00566239760926e-22 215.258329609056 39.755142569459 5.41460338704515 1.35064068130684e-07 -371.646712605699 70.3800135531454 -5.28057176807817 2.63876787127837e-07 LRRC42 other 3.01310661992839e-18 0.00415685102762482 0.00158524696764984 5.41460338704515 -5.28057176807817 2.6843225488571e-16 170.5014805535 37.2766197621466 4.57395229614245 7.32168326601238e-06 -232.323399814244 58.6068324460819 -3.96410094382734 9.45602602967211e-05 WRAP73 other 3.66678460173879e-12 1 0.0760356807175386 4.57395229614245 -3.96410094382734 2.60968411090269e-23 553.983822471047 77.9353132645929 7.10825169317347 1.03505860084667e-11 -501.611146455526 138.057092110103 -3.63336021923078 0.000334361166599911 MRPL37 other 3.95053980708449e-19 1 1.42341258788434e-07 7.10825169317347 -3.63336021923078 1.51465661550728e-15 545.579350387729 118.204438150782 4.61555724068318 6.07624796815822e-06 -685.778257200416 185.579240425156 -3.69533928271999 0.000266030469407331 ICMT other 2.03160891837991e-11 1 0.063484638771317 4.61555724068318 -3.69533928271999 8.70598660797287e-13 1506.47017943672 255.611828910974 5.8935855427935 1.12757076719709e-08 -424.693703381065 401.306835809952 -1.05827677349156 0.290878659606891 RPL22 other 1.07553758554897e-08 1 0.000139706018055719 5.8935855427935 -1.05827677349156 0.555271802060106 265.21151081599 247.086368984994 1.07335549065476 0.284073563138208 189.137383625411 753.534130628572 0.251000420468863 0.802005405070746 QSOX1 other 1 1 1 1.07335549065476 0.251000420468863 2.07156674192508e-20 109.622996598828 32.1804397929864 3.40651020632476 0.000758178945102821 -264.447489134811 48.0752578817872 -5.50069829651385 8.77698777887536e-08 STXBP3 other 3.04396017058472e-16 0.00138772953771798 1 3.40651020632476 -5.50069829651385 1.09136599982214e-12 151.11312335468 37.113474594979 4.07165119956522 6.13771242051851e-05 -199.986428558092 58.7725595282251 -3.40271769961031 0.000768337472695487 PHF13 other 1.34303499938112e-08 1 0.588483866879315 4.07165119956522 -3.40271769961031 0.00133016758523008 915.523018820874 311.558506950509 2.9385267883772 0.00358059206029733 -173.265541055082 498.595798053676 -0.347507022183988 0.728479191326451 ERRFI1 other 1 1 1 2.9385267883772 -0.347507022183988 5.67562870124486e-20 997.331797946117 149.435749158903 6.67398399351953 1.39183919527269e-10 -741.103347237112 239.146211537943 -3.09895499690794 0.00214562374627519 PARK7 other 8.29266109538887e-16 1 1.8522596010689e-06 6.67398399351953 -3.09895499690794 0.25392687355408 -267.396339793043 236.242219419764 -1.1318736356685 0.25868443600056 -583.108890715166 352.223065114062 -1.65551023901951 0.0989742891415508 KIAA1324 other 1 1 1 -1.1318736356685 -1.65551023901951 0.129141598171506 17.5596613016096 12.4160533217509 1.41427077079703 0.158430250163623 -7.75559132260315 18.045558713337 -0.429778398430591 0.667698373805317 OPRD1 other 1 1 1 1.41427077079703 -0.429778398430591 4.85091009465938e-11 231.482159772656 61.10616434248 3.78819653079964 0.00018669223767867 -218.556062519735 90.9810442839552 -2.40221536518765 0.0169642918701996 AMPD2 other 5.59892043125585e-07 1 1 3.78819653079964 -2.40221536518765 1.20257795207972e-19 506.629486354095 99.0985488682611 5.11238047519338 6.01938383018491e-07 -641.590090972705 144.030364212105 -4.45454744548081 1.23070081377859e-05 SRSF4 other 1.74914963129996e-15 0.189023337988253 0.00677361262410708 5.11238047519338 -4.45454744548081 8.76930890056665e-19 54.6632507891345 17.5107889746121 3.12168976899828 0.00199198230099882 -154.144953985684 25.4168835117552 -6.06466775969576 4.40856273442426e-09 MECR other 1.25848352032032e-14 7.01137817282834e-05 1 3.12168976899828 -6.06466775969576 2.91069212160093e-06 -18.4249507600121 42.5975547173592 -0.432535409186379 0.665693800789291 -271.108057314057 63.2787816394648 -4.284343824107 2.54242332039563e-05 KCNC4 other 0.0249213459451472 0.387211071696255 1 -0.432535409186379 -4.284343824107 1.11451044948801e-05 162.4980424983 36.3800440640766 4.46668074981137 1.16590704203478e-05 -194.577910653781 111.814195414439 -1.74018969534752 0.082956705790875 EDEM3 other 0.0908771820512523 1 0.119109063414273 4.46668074981137 -1.74018969534752 2.65268411563279e-20 239.739373069733 68.6183568771298 3.49380812920103 0.000555681464392337 -540.768192080452 100.552587949249 -5.37796394015625 1.6240272723241e-07 WDR77 essential 3.89254867127955e-16 0.00256271503572742 1 3.49380812920103 -5.37796394015625 1.51344442363391e-17 295.203936570038 144.354266566759 2.04499626918554 0.0418175377125881 -1249.84714456158 211.535159764825 -5.90846054126935 1.02942564112828e-08 ATP5F1 essential 2.1269947929751e-13 0.000163555145862462 1 2.04499626918554 -5.90846054126935 5.86621317322862e-07 54.6989651815291 84.1719351180902 0.649848017688894 0.516336826439624 -474.456238334375 123.690484055968 -3.83583459920564 0.00015547535616176 RAP1A other 0.00532358845470497 1 1 0.649848017688894 -3.83583459920564 2.26723584300611e-15 759.842120540277 215.575913751205 3.52470787352063 0.000498395458107863 -1449.3263230461 308.100677625261 -4.70406730104274 4.08892614715065e-06 HDAC1 other 3.02630640324456e-11 0.0633947109854236 1 3.52470787352063 -4.70406730104274 4.3313880051607e-19 436.955902801924 214.511726614476 2.0369790952605 0.042620262867134 -1947.29453173885 314.904475104624 -6.18376265085429 2.28508080795807e-09 CAPZA1 other 6.24975975264638e-15 3.63670610586527e-05 1 2.0369790952605 -6.18376265085429 4.77737554408819e-10 142.827081811541 33.5702713914747 4.25457036513005 2.89099827375796e-05 -103.251095690285 47.8734729678573 -2.15674964211619 0.0319079810426292 S100PBP other 5.25415762338819e-06 1 0.2859486392574 4.25457036513005 -2.15674964211619 2.08524619075323e-05 79.8763305394126 130.488853216637 0.612131447019481 0.540965933624598 -672.368917228024 185.670698460085 -3.62129793664007 0.000350029482377015 RNF19B other 0.16604815416968 1 1 0.612131447019481 -3.62129793664007 3.30237713020209e-10 336.027791690668 49.8526969819787 6.74041349883515 9.59031769621071e-11 -160.417216573591 166.96719212296 -0.960770882793875 0.337530177162127 SCAMP3 other 3.66233623739411e-06 1 1.28270499186818e-06 6.74041349883515 -0.960770882793875 2.05161466877359e-05 39.482691768663 16.5585045001371 2.38443585097531 0.0177935572475763 -52.8823729328226 23.9246789967363 -2.21036917318876 0.027915142463181 TRIM62 other 0.163534205247943 1 1 2.38443585097531 -2.21036917318876 0.0338828159227079 13.7224916947047 6.74189695470503 2.03540513699606 0.0427829695442271 -3.25997431461415 9.68686733872522 -0.336535455748604 0.7367275687813 DLGAP3 other 1 1 1 2.03540513699606 -0.336535455748604 2.07262875580307e-07 1344.89490389908 312.877253344285 4.2984745280258 2.39810077459647e-05 -427.792390400449 449.057432016368 -0.952645162734678 0.341615671227563 SFPQ other 0.00194516208732118 1 0.238682970095587 4.2984745280258 -0.952645162734678 0.149536704654842 24.5280388252861 36.503970436245 0.671927972003071 0.502199865121271 195.841967811514 102.849816542175 1.90415476075454 0.0579451200711285 RHOU other 1 1 1 0.671927972003071 1.90415476075454 2.5857346593554e-09 379.354916627706 58.9911129642595 6.43071299328669 5.74251069236293e-10 -104.683476760225 193.539278398352 -0.540890085085265 0.589029297491779 GON4L other 2.72950150641557e-05 1 7.48191718107966e-06 6.43071299328669 -0.540890085085265 0.000149738660227993 464.899563659029 109.464287184564 4.24704326512608 2.98349339552213e-05 -10.149591074633 359.132725041584 -0.0282613929807086 0.977474549851285 ARHGEF2 other 1 1 0.294619972807811 4.24704326512608 -0.0282613929807086 2.72886387931838e-09 155.453734171617 24.0348759255528 6.46784009425008 4.62048402622909e-10 -17.0730862055356 79.1129503600131 -0.215806465665134 0.829300947362713 LAMTOR2 essential 2.87785984712917e-05 1 6.03989671908666e-06 6.46784009425008 -0.215806465665134 0.00148280775607597 171.110015361343 46.991603467989 3.64128913962054 0.000324695075149517 -7.6045802600874 156.622209880033 -0.0485536519112599 0.961310639008235 MEF2D other 1 1 1 3.64128913962054 -0.0485536519112599 2.03603273783567e-57 478.749411547452 23.6113274942912 20.2762598444838 2.15308615030046e-56 144.708197992842 73.5000580124503 1.9688174663526 0.0499854594855181 DOCK7 other 3.24482537428871e-53 1 3.43180401496391e-52 20.2762598444838 1.9688174663526 5.27470194562964e-11 301.789856071025 92.1116240269727 3.27634931268449 0.00118756388733014 -515.370764788619 144.238354283582 -3.57304939694034 0.000417004561928057 SRM other 6.07803905194903e-07 1 1 3.27634931268449 -3.57304939694034 3.66482173421612e-05 84.8916146007017 57.2763860284815 1.48213985705188 0.139456448436206 -255.129953156709 89.6895668416413 -2.84458897663287 0.00478348164893774 FBXO2 other 0.284573407661882 1 1 1.48213985705188 -2.84458897663287 8.6577175159227e-05 1.73732341898133 28.2428962634002 0.0615136423254409 0.950995159781125 -161.563289889143 44.2257849676158 -3.65314691434979 0.000310528138227017 FBXO6 other 0.646644921264267 1 1 0.0615136423254409 -3.65314691434979 0.0027112382222757 148.708779899274 46.0728568013704 3.22768741127531 0.00140083902567333 -160.162806424639 141.605089994293 -1.13105260856861 0.2590292120652 C1orf21 other 1 1 1 3.22768741127531 -1.13105260856861 3.18227605090538e-08 27.6922230306723 5.01895109954431 5.51753194670229 8.03063208880194e-08 -34.9738618145649 15.4035527510077 -2.27050618645604 0.0239620175813291 SWT1 other 0.000314536164871488 1 0.000953878479507895 5.51753194670229 -2.27050618645604 6.83444154143128e-19 425.611310872552 76.656489554646 5.55218890592618 6.70380276529223e-08 -463.054162178227 119.956377275859 -3.86018795076948 0.000141604272768164 MAD2L2 essential 9.83271104565718e-15 1 0.000799361441733445 5.55218890592618 -3.86018795076948 0.0125446931285072 34.6734680035024 12.8297039632735 2.7025929906691 0.0073129207574261 -26.373995584989 50.6875609052456 -0.520324811728308 0.603260457499617 DNAJC6 other 1 1 1 2.7025929906691 -0.520324811728308 0.0189762874716042 59.2348835201697 21.5957297344774 2.74289798253965 0.00649445381815314 1.02739514348788 85.3203526241189 0.0120416185809041 0.990401237913063 LEPR other 1 1 1 2.74289798253965 0.0120416185809041 0.155476776765177 324.22327816666 278.23195136298 1.16529850931348 0.244926629443969 -1273.83199637694 854.056440715856 -1.49150797962396 0.136995589596319 IVNS1ABP other 1 1 1 1.16529850931348 -1.49150797962396 7.44767248865821e-20 1176.94585059732 175.833820678034 6.69351235194054 1.23411993467996e-10 -759.596651793076 275.903720025521 -2.7531221823425 0.00629898331139579 MFN2 essential 1.08646646264546e-15 1 1.64557552090227e-06 6.69351235194054 -2.7531221823425 0.930213145262735 -80.1518330192373 262.506895992187 -0.305332295048062 0.760354594812027 -191.178007720055 813.886265991128 -0.234895237465696 0.814472825045419 PRG4 other 1 1 1 -0.305332295048062 -0.234895237465696 1.13679437015013e-14 125.873160491927 31.091282819418 4.04850328058235 6.71956923809258e-05 -196.701584806955 48.785839704583 -4.03194012848931 7.18247280479663e-05 MIIP other 1.48920062489667e-10 1 0.641517275160698 4.04850328058235 -4.03194012848931 2.12252655061772e-08 704.895253224707 115.178240193237 6.12003840345268 3.25161466482469e-09 -55.1624098486789 354.905113999007 -0.155428613657095 0.876598709255436 SMG7 essential 0.000211957495787257 1 4.12239707206475e-05 6.12003840345268 -0.155428613657095 0.912635827055495 25.9869894600295 60.8381579724598 0.427149511525206 0.669608359842279 0.936664488789748 187.463998012823 0.00499650332180411 0.996017046267877 NCF2 other 1 1 1 0.427149511525206 0.00499650332180411 0.000108177634648504 22.5571383147855 36.9179863113289 0.611006735973122 0.54170537705607 -182.883999780714 56.9256108814421 -3.21268400898855 0.00147324494950196 SLC35D1 other 0.798350943705959 1 1 0.611006735973122 -3.21268400898855 0.467916760129519 66.3714917886638 54.0463165412581 1.22804838583212 0.220526699671425 26.1293220704732 164.140417415357 0.159188836496943 0.873642276446096 PLA2G4A other 1 1 1 1.22804838583212 0.159188836496943 0.000171593805744652 71.4761042886556 99.0218318973745 0.721821672242268 0.471026461452672 -464.305054358864 152.848385406343 -3.03768373558231 0.00261659151661789 GADD45A other 1 1 1 0.721821672242268 -3.03768373558231 8.4627620311042e-05 413.020740600907 154.658130912865 2.67054010133878 0.00803072785481306 -331.966218901518 238.727613366047 -1.39056481242706 0.165498289465363 WLS other 0.632760717065661 1 1 2.67054010133878 -1.39056481242706 3.99672893302214e-11 286.894052747274 58.2656249005282 4.92389900970019 1.47080846036456e-06 -184.426890281752 97.7673030610499 -1.88638618952788 0.0603041994423685 PRDM2 other 4.62821210443964e-07 1 0.0161200607255956 4.92389900970019 -1.88638618952788 0.635685995711256 -27.3675375047033 131.893047737589 -0.207497953638565 0.835782179827091 330.42006100255 361.91599579959 0.912974460475406 0.362095314483858 RGS2 other 1 1 1 -0.207497953638565 0.912974460475406 4.0912697308862e-07 150.744417324959 28.9335470696536 5.21002201914828 3.83703092632742e-07 -129.470001945074 79.4017257327395 -1.63056911862168 0.104187389080883 TROVE2 other 0.00376355902544222 1 0.00437459895910589 5.21002201914828 -1.63056911862168 0.0740174121934278 -7.90996500882254 3.53237195285761 -2.23927862478456 0.0259432742309373 -5.51813360449005 5.18770356175632 -1.06369485819692 0.288406905643277 AMPD1 other 1 1 1 -2.23927862478456 -1.06369485819692 2.9651566524185e-06 159.402182810936 30.9645104539209 5.14789933618188 5.17654323962583e-07 -10.2856539924094 84.9669624563828 -0.121054745221584 0.903740460371147 UCHL5 other 0.0253698803180927 1 0.00584638793483341 5.14789933618188 -0.121054745221584 1.04042566356449e-23 161.217116250601 42.1839241974318 3.82176668761452 0.000164138390787835 -356.73466719963 61.8495784066553 -5.76777847787631 2.1719862043381e-08 BCAS2 essential 1.57978232755633e-19 0.000344629051042326 1 3.82176668761452 -5.76777847787631 5.21670504624615e-12 938.480769230761 189.632069017614 4.94895601831772 1.31499326270061e-06 -564.115384615389 297.777121973836 -1.89442150852997 0.0592376103229148 SRSF11 essential 6.24856930439364e-08 1 0.0144596659166559 4.94895601831772 -1.89442150852997 3.53129226574944e-06 35.4775428586206 9.70611946990437 3.65517269477522 0.000308601308226279 -13.4548314529266 15.2251215854496 -0.88372571459693 0.377627605286428 CTH other 0.0300265781356675 1 1 3.65517269477522 -0.88372571459693 0.0188866651610272 12.560578471688 12.7061201393597 0.988545546077373 0.3237608731055 -33.6985175694447 19.6971572277715 -1.71083152658864 0.0882481648983203 AGMAT other 1 1 1 0.988545546077373 -1.71083152658864 0.740184351571008 -38.2571529595319 119.652859758351 -0.319734547396488 0.74941411633417 -131.36989915449 175.863731122469 -0.746998248678155 0.455707482077796 OLFML3 other 1 1 1 -0.319734547396488 -0.746998248678155 0.916142969066854 -0.410802292298039 3.91238314658492 -0.105000527020628 0.916452777612238 -2.71206379292606 6.78609258047433 -0.399650278973426 0.689727759836612 TNNI3K other 1 1 1 -0.105000527020628 -0.399650278973426 0.3726402832881 2.23404083787221 3.23242561650261 0.691134492458754 0.490086005727375 -10.2222808743432 9.00112009199632 -1.13566764690015 0.257121740756762 CFHR3 other 1 1 1 0.691134492458754 -1.13566764690015 2.06826102438636e-14 463.28101500295 101.420193080947 4.56793663006724 7.4639331578835e-06 -545.738521085227 157.530841400406 -3.46432810384151 0.000617046754694941 PLEKHM2 other 2.68956663611202e-10 1 0.0774308425798834 4.56793663006724 -3.46432810384151 0.00150170773608394 126.675769074157 61.5173396590059 2.05918802367475 0.0404281168514658 -157.255618136109 106.70283215868 -1.47377173552667 0.141699415104198 CRYZ other 1 1 1 2.05918802367475 -1.47377173552667 0.000179432956762757 28.7590265818233 23.8750738753688 1.20456283117486 0.229415348043505 -81.3857795097057 35.0911760991478 -2.31926622464164 0.0211188385054335 PHTF1 other 1 1 1 1.20456283117486 -2.31926622464164 2.75610243189682e-17 181.691248433354 33.2718953801973 5.46080246878548 1.06613611826692e-07 -178.041923473902 51.6795473860464 -3.4451138308919 0.000660630252026528 ZBTB17 essential 3.85358242027813e-13 1 0.0012585736876141 5.46080246878548 -3.4451138308919 2.61098743564277e-07 -19.4305505543694 26.8909619360582 -0.722568073264605 0.47056837602619 -226.878345009738 45.784025825283 -4.95540400653125 1.27311752726048e-06 CD58 other 0.0024331791912755 0.0198937344809723 1 -0.722568073264605 -4.95540400653125 0.0901471749477297 1.22420461796922 7.02431250849416 0.174281058322625 0.86177470785624 -17.9335043692292 10.0569158815545 -1.78320119015027 0.0756726997200256 TFAP2E other 1 1 1 0.174281058322625 -1.78320119015027 0.173694057224885 -56.7017702232597 37.3511300810602 -1.51807375306194 0.130157220793075 0.0700188336036182 63.3761087064517 0.00110481433828534 0.999119295718055 CD2 other 1 1 1 -1.51807375306194 0.00110481433828534 5.00755976680088e-14 292.111428869785 50.6741594915159 5.76450466669687 2.24032029727732e-08 -120.544326018644 86.9698546547019 -1.38604722863161 0.16688035276232 TTF2 essential 6.44422866389605e-10 1 0.000273341479470806 5.76450466669687 -1.38604722863161 0.506212345862778 6.25463272168972 5.59099020308524 1.11869856581724 0.264259385466108 7.08645964329725 15.1691679212099 0.467162053983778 0.640759327179155 NR5A2 other 1 1 1 1.11869856581724 0.467162053983778 0.908460612755571 6.6813952628651 15.5384923368217 0.429989931972496 0.667542178272355 5.66716257899648 42.78072780319 0.132469989876467 0.894710142092756 KIF21B other 1 1 1 0.429989931972496 0.132469989876467 1.1800508050104e-05 565.646134092892 118.393496516536 4.77767910177303 2.89916684534649e-06 -121.854787853214 325.962122859203 -0.37383112732349 0.708820116258423 TMEM9 other 0.0960561355278469 1 0.0310906652494957 4.77767910177303 -0.37383112732349 2.29535054685103e-26 137.453984324088 32.9640552871182 4.16981415444364 4.10669771859676e-05 -358.853511592528 47.0973721527369 -7.61939563058347 4.28605726360655e-13 ADPRHL2 other 3.54057821851772e-22 6.84269042134786e-09 0.399951290814139 4.16981415444364 -7.61939563058347 4.33192341731065e-07 188.016530116978 160.710377333118 1.16990908264287 0.243065416769365 -929.454602044138 229.614845143841 -4.04788549913611 6.7490053767427e-05 MAP7D1 other 0.00397540612006598 1 1 1.16990908264287 -4.04788549913611 2.99236214551747e-29 109.307120175668 14.5487536855848 7.51316040795798 9.75164310940032e-13 -115.553680950724 25.7277969901436 -4.4913943076818 1.07310844406913e-05 WARS2 other 4.67377043508373e-25 0.165033347613392 1.37420154697669e-08 7.51316040795798 -4.4913943076818 0.000519808500785794 34.6946401914754 14.3027601527546 2.42573040594499 0.0159308914336135 -28.7144173595417 20.4350590926494 -1.40515460363266 0.16112058713416 OSCP1 other 1 1 1 2.42573040594499 -1.40515460363266 4.01609137632458e-09 237.677626382423 98.5351618409076 2.41210976814725 0.0165252792409973 -544.38146804118 140.782047200513 -3.86683869759209 0.000138106132031926 MRPS15 other 4.18677525981837e-05 1 1 2.41210976814725 -3.86683869759209 2.26944687262782e-06 64.092753104952 12.4461677863409 5.14959738653779 5.01544549163218e-07 -9.10360351971112 35.0996581672304 -0.259364449543568 0.795550246883229 EXOC8 other 0.0196125598732496 1 0.00566895803919186 5.14959738653779 -0.259364449543568 5.87291828194177e-20 326.715464355289 32.875490844069 9.93796460423743 4.69337950343433e-20 -115.904108109316 92.7127538785958 -1.25014200593252 0.212322154672147 GNPAT other 8.57857173443234e-16 1 7.18838004746001e-16 9.93796460423743 -1.25014200593252 1.67745879597784e-10 304.986356502203 44.9277857593267 6.78836829698179 7.13793514941846e-11 -119.733103776069 127.626394547674 -0.938153147712272 0.349001067655011 TSNAX other 1.88747663723427e-06 1 9.58267793809428e-07 6.78836829698179 -0.938153147712272 2.59394762014717e-10 42.3795517998179 24.1950884828932 1.75157664043187 0.0809820402695464 -180.566115605531 37.1590970073807 -4.85927081515641 2.0001170158355e-06 C1orf109 essential 2.89328917551215e-06 0.0311638232237329 1 1.75157664043187 -4.85927081515641 6.84008216660449e-08 105.609131262469 54.9501933598157 1.92190645392158 0.0556698899325344 -336.122902112002 86.904334926868 -3.86773458878498 0.000137737457615125 RRAGC other 0.000661709548797318 1 1 1.92190645392158 -3.86773458878498 1.09344549553545e-17 210.533081933493 22.7193940073562 9.26666802227761 5.97330022390141e-18 -53.0574791452407 61.5346527870934 -0.862237401888277 0.389313654293834 TBCE essential 1.54000863591213e-13 1 9.01908600806874e-14 9.26666802227761 -0.862237401888277 0.922945951557208 76.8844584193556 248.137172885963 0.309846596240095 0.756913997405359 199.636854717358 687.728528848935 0.290284387433358 0.771819058587712 NID1 other 1 1 1 0.309846596240095 0.290284387433358 8.19983838559669e-06 272.939645901218 66.4081847026553 4.11003021876465 5.23654940927879e-05 -429.933659850077 185.45159316376 -2.31830664010759 0.0211717059570539 LGALS8 other 0.0676486666811727 1 0.50469863206629 4.11003021876465 -2.31830664010759 0.182257429228897 5.64011287390318 4.00594599754883 1.40793532348021 0.160300537191058 -7.76494731488026 10.9475534464396 -0.709286084134676 0.478758987496871 HPCAL4 other 1 1 1 1.40793532348021 -0.709286084134676 0.000336017830346044 170.832522776643 42.0862069790814 4.05910950496332 6.44431258372662e-05 48.6256606037027 117.216102846355 0.414837717881137 0.678587708254932 MTR other 1 1 0.616462941759289 4.05910950496332 0.414837717881137 0.00100083805381669 36.6156207949764 10.4205492437743 3.51378991053204 0.000517787967371504 -5.60710957427323 28.567873459707 -0.196273257167064 0.844543937657465 BMP8B other 1 1 1 3.51378991053204 -0.196273257167064 0.00940395870272908 242.021863281291 88.6076081472952 2.73138919266357 0.00672393825588389 -123.64970482499 243.149696737042 -0.50853324714903 0.611496230168516 MYCL other 1 1 1 2.73138919266357 -0.50853324714903 0.122604303740153 219.84030629493 122.5833111953 1.79339507271654 0.0740165112351507 416.652018517231 344.655735356043 1.2088933268057 0.22774980042403 SIPA1L2 other 1 1 1 1.79339507271654 1.2088933268057 2.54003765835206e-12 201.987128666697 33.8612753754421 5.96513647011621 7.67040032299792e-09 -98.9441931321797 57.8923334528319 -1.70910701350111 0.0885844611627033 RLF other 3.0828437059419e-08 1 9.56805736290761e-05 5.96513647011621 -1.70910701350111 0.893667763153198 13.842897188486 33.3350163032004 0.415265949252197 0.678277029734283 -16.4940684685664 89.3633466981738 -0.184573083685814 0.85370245641808 KMO other 1 1 1 0.415265949252197 -0.184573083685814 3.71161395201465e-21 21.1117524844104 2.60564955173742 8.10229927901598 1.83617906990543e-14 -14.6580718208173 5.21152766421281 -2.81262477439644 0.00527192996814059 ZNF684 other 5.50506581362813e-17 1 2.66484668415375e-10 8.10229927901598 -2.81262477439644 0.0260698002855229 13.2754989854165 4.91253232429283 2.70237386933176 0.00731761400065378 8.45551333075706 9.82549556302408 0.860568637634663 0.390233577376464 KCNQ4 other 1 1 1 2.70237386933176 0.860568637634663 0.000846141058575426 55.3474267510655 19.6062419692474 2.82294928512453 0.00510985053436837 -44.7575811417238 39.2142037465673 -1.1413614676708 0.254723378481061 RIMS3 other 1 1 1 2.82294928512453 -1.1413614676708 1.5716274412252e-05 317.895172475504 66.3113402198209 4.79397899999739 2.69943119649342e-06 150.60281935415 180.110077085011 0.836170978279392 0.403795388093552 AKT3 og 0.126578874116278 1 0.0290161859311077 4.79397899999739 0.836170978279392 0.0292786008026168 114.45365790796 45.5093821681713 2.51494642324562 0.0124842086116607 -106.14583381201 145.994047142162 -0.727055903235906 0.467819300311857 ETV3 other 1 1 1 2.51494642324562 -0.727055903235906 1.39662041249883e-11 187.63968175927 47.5541203614177 3.94581332454861 0.000101379179359488 -265.961496253457 81.752800216351 -3.25324020155414 0.00128561992000205 ACADM other 1.64898972103736e-07 1 0.9504298064952 3.94581332454861 -3.25324020155414 0.865059151694591 -0.962181269597147 19.2070363392351 -0.0500952490849229 0.960083661848501 14.0077309631774 32.4320979152263 0.431909492866974 0.666153182732591 ST6GALNAC5 other 1 1 1 -0.0500952490849229 0.431909492866974 0.168638209017853 -10.8287678201983 6.0886608672763 -1.7785138729598 0.0764364060400228 11.7835234531333 22.3236156211249 0.527850132036071 0.598033695303773 SLAMF1 other 1 1 1 -1.7785138729598 0.527850132036071 0.729449729718508 -10.3100694315464 35.4921203655097 -0.290488968406787 0.771663542527916 93.5224808655442 130.129181094097 0.71868953665295 0.47294915332964 CD48 other 1 1 1 -0.290488968406787 0.71868953665295 0.0224684400565349 266.711412093057 152.01178367088 1.75454432315926 0.0804674361841161 -192.127197011181 231.064587387415 -0.831486984585184 0.406430605319941 ADGRL2 other 1 1 1 1.75454432315926 -0.831486984585184 0.494347986313892 -34.6597857187033 259.088068037107 -0.133776078463557 0.893678206094481 -403.745364560233 388.052486368367 -1.04044009185131 0.299056037623116 PADI2 other 1 1 1 -0.133776078463557 -1.04044009185131 3.72913030055351e-14 262.008176361 80.0567944920644 3.27277875692327 0.00120208696978366 -521.248659227338 120.322156939634 -4.33210866963471 2.07717797392793e-05 SDHB ts 4.81803634831514e-10 0.317039674160621 1 3.27277875692327 -4.33210866963471 0.00210609540656783 442.309471238988 228.761785203231 1.93349370326885 0.0542091716525739 -446.892642006904 343.819804373289 -1.29978737793041 0.194770269056621 MFAP2 other 1 1 1 1.93349370326885 -1.29978737793041 6.52129763986633e-35 236.378737760988 25.0822763797974 9.42413416476746 1.93479305836727e-18 -198.555231519766 43.0552856553434 -4.61163428595495 6.14591515129212e-06 RPF1 essential 1.03010417519329e-30 0.0949236595117068 2.93333975579062e-14 9.42413416476746 -4.61163428595495 0.182449464694792 180.625322714057 131.019276423605 1.37861639633902 0.169141674686352 -404.410066172048 369.676389305345 -1.09395697932446 0.274938139039851 KDM5B other 1 1 1 1.37861639633902 -1.09395697932446 5.87510210934362e-06 200.583150087063 42.291787354571 4.74283927528033 3.40002538664481e-06 -197.261683815382 146.120765450644 -1.34999076419437 0.178137168258263 UAP1 other 0.0490159768982538 1 0.0362306705200871 4.74283927528033 -1.34999076419437 0.466029655174147 44.7625513251211 54.975155004765 0.814232380449701 0.416224102352921 -23.2377795310328 82.780257616215 -0.280716443753625 0.779141296311272 ACTL8 other 1 1 1 0.814232380449701 -0.280716443753625 3.55662323571075e-09 17.2274682311724 27.7634547666809 0.620508808285893 0.535440509520067 -246.58114568399 47.6576949260259 -5.17400487091816 4.44366696968351e-07 CTBS other 3.71844959293559e-05 0.00698544447634248 1 0.620508808285893 -5.17400487091816 0.86823269062172 2.62814242122756 16.4423537316986 0.159839793262741 0.873125473826466 -26.9274702594345 54.5398351404525 -0.493721152440049 0.621900095289812 RGS4 other 1 1 1 0.159839793262741 -0.493721152440049 4.22491778330665e-12 275.772699196482 37.1105093745194 7.43112136816509 1.38801518533256e-12 -89.6159443123553 104.708860293956 -0.855858272745693 0.392826725051903 KLHL12 other 5.07961865086959e-08 1 1.94960612931812e-08 7.43112136816509 -0.855858272745693 0.319939606466545 -7.39343038447189 19.2052575976774 -0.384969081870896 0.700561170881306 -40.8448708812651 28.918811986682 -1.41239795397112 0.158975926229536 IGSF21 other 1 1 1 -0.384969081870896 -1.41239795397112 1.04816447758577e-14 275.743701282497 44.5606385243886 6.18805543218548 2.22150157037509e-09 -136.333043005965 76.4911043798788 -1.78233853611123 0.0758053305506982 SSX2IP other 1.37445807945823e-10 1 2.83330310285638e-05 6.18805543218548 -1.78233853611123 1.13985482672859e-17 181.752533432501 26.073570754213 6.97075729081463 2.36868508985606e-11 -84.5597723702946 44.7569040337046 -1.88931236858153 0.0599096259252365 ZNHIT6 essential 1.60468762506851e-13 1 3.22425414431207e-07 6.97075729081463 -1.88931236858153 0.195598770129862 -69.3785453079721 39.862059843614 -1.74046563524706 0.0829040452159769 -36.6932472837223 58.4556195494699 -0.627711203243162 0.530717838854839 PLA2G2D other 1 1 1 -1.74046563524706 -0.627711203243162 2.7001689130202e-11 153.28107091648 21.5288908934891 7.11978483586611 9.71596691997572e-12 -61.5687875508241 62.0435602050897 -0.992347752890127 0.321913125148286 RBBP5 essential 3.14731688501635e-07 1 1.33750000620386e-07 7.11978483586611 -0.992347752890127 0.0614692314742898 -78.1567772510475 58.7816583435153 -1.32961164168431 0.184760250265302 -252.014388395564 106.38554333336 -2.36887814358268 0.0185409896400809 GBP3 other 1 1 1 -1.32961164168431 -2.36887814358268 0.684780003600356 -139.657901197562 160.392864371805 -0.870723904985089 0.384672739212746 -123.825314450117 290.285822207852 -0.426563424656181 0.670034747953748 GBP1 other 1 1 1 -0.870723904985089 -0.426563424656181 1.31804080791989e-12 213.953211646788 77.8795552317542 2.74723206893138 0.0064100765659273 -483.071810556122 114.206282093038 -4.22981820004075 3.19527571604783e-05 PINK1-AS other 1.61670885499454e-08 0.485106759210382 1 2.74723206893138 -4.22981820004075 0.123269864208818 11.7055468184428 8.56722960125821 1.36631645972506 0.172968121761023 -5.38090747964935 12.5530692847874 -0.428652734847109 0.66851522913648 KIF17 other 1 1 1 1.36631645972506 -0.428652734847109 0.0325979852823526 149.398081306991 81.252071243341 1.83869874356261 0.0670456464853682 -388.522606382979 229.744082986559 -1.69111039262635 0.0919569491389075 CDK18 other 1 1 1 1.83869874356261 -1.69111039262635 0.0139670808482813 91.912020438232 31.9040635697309 2.88088757839091 0.00428023498693905 -29.1101975327141 90.2102520737086 -0.322692785615197 0.747174917436837 RAB29 other 1 1 1 2.88088757839091 -0.322692785615197 0.747759064726393 0.888801559782513 1.5210000875041 0.584353391616826 0.559513756322114 2.59408520034279 5.12754967456815 0.505911276337126 0.613368324864012 CD160 other 1 1 1 0.584353391616826 0.505911276337126 0.00120035989371002 353.397760101047 664.906871766973 0.531499635673642 0.59550478743994 -2573.09423162194 977.24511617274 -2.63300802330857 0.0089455495506487 ECE1 other 1 1 1 0.531499635673642 -2.63300802330857 2.2417205079236e-14 122.793722760457 39.749624684708 3.0891794258298 0.00221498657585025 -265.251308083388 58.7841535877022 -4.51229271656774 9.55243783681296e-06 HMGCL other 2.91289162799592e-10 0.147040675622062 1 3.0891794258298 -4.51229271656774 5.84942401411695e-08 128.96121205973 89.8319373051387 1.43558311140144 0.152269962239768 -508.83822685931 132.848912197594 -3.83020243404389 0.000159012324216164 GALE other 0.000568330037211603 1 1 1.43558311140144 -3.83020243404389 0.129326744911914 -134.770721562598 156.961802784627 -0.858621136936879 0.391305580673181 -462.640303405112 232.124624961397 -1.99306860908037 0.0472528660679547 ID3 other 1 1 1 -0.858621136936879 -1.99306860908037 0.716332094512409 -44.6517396522801 56.0413244043588 -0.796764532724125 0.426285266756472 15.5556078079048 157.012627678254 0.0990723360147884 0.92115408051229 CR2 other 1 1 1 -0.796764532724125 0.0990723360147884 0.00129179983102596 985.785574877202 272.199202465253 3.62155937985542 0.00034969235963047 -251.512423950709 763.684663593347 -0.329340676775246 0.742153537188635 CD46 other 1 1 1 3.62155937985542 -0.329340676775246 1.10399678909795e-08 283.40026658703 45.2140335869877 6.26797133774392 1.49007795201536e-09 -0.468462192402387 153.47323249214 -0.00305240324189026 0.997566852348308 PRPF3 essential 0.000112188153708133 1 1.91355810597812e-05 6.26797133774392 -0.00305240324189026 1.61893638987139e-15 1325.64057367198 151.025832098764 8.77757503633599 2.1653315677654e-16 -304.025576018404 512.637798559143 -0.593061176668831 0.553649841544416 APH1A other 2.16921286878868e-11 1 3.2239621712459e-12 8.77757503633599 -0.593061176668831 2.70790290648151e-07 210.031224039289 61.8694435813244 3.39474887572269 0.000789700864624995 -285.578043856582 115.853603084607 -2.46499061102163 0.0143220565317054 P3H1 other 0.00252105760593429 1 1 3.39474887572269 -2.46499061102163 0.00533268872512901 5964.52528498188 2221.76669100511 2.68458668911072 0.00771111917591737 -1762.8414311672 4190.46149718698 -0.420679543852289 0.674323735374907 SLC2A1 other 1 1 1 2.68458668911072 -0.420679543852289 1.23226141638484e-15 584.732987352919 83.6102682463405 6.99355473457068 2.12084401850181e-11 -226.869199828422 157.57677495843 -1.43973754944707 0.15110437802467 CDC20 essential 1.65615934362123e-11 1 2.89028622841427e-07 6.99355473457068 -1.43973754944707 0.730971147528696 40.055064975128 57.3006613097872 0.699033205892276 0.485130777424915 70.6369940487665 106.801644512618 0.661384891319919 0.508927430486636 ARTN other 1 1 1 0.699033205892276 0.661384891319919 4.71372511075569e-08 181.548258975051 49.4509338452215 3.67128069903162 0.000290652308743132 -221.916586331444 92.170682442931 -2.40766999277505 0.0167232143624452 IPO13 essential 0.000460751550516915 1 1 3.67128069903162 -2.40766999277505 3.99551576824569e-10 401.079975321021 199.211372706602 2.013338746035 0.0450675827964653 -1778.38833404028 371.306398989974 -4.78954399621942 2.75500455883913e-06 ATP6V0B essential 4.41544447548832e-06 0.0428540959127426 1 2.013338746035 -4.78954399621942 4.41106357712051e-12 326.332317896117 74.1346448171264 4.40188684657633 1.54519732846833e-05 -460.506105476934 138.178195518933 -3.33269734597045 0.000979828053381218 B4GALT2 other 5.29592293069089e-08 1 0.156219449908149 4.40188684657633 -3.33269734597045 7.07815100380873e-23 344.287011908746 56.6978272258461 6.07231403308169 4.24497607073337e-09 -503.96413084336 99.521847628041 -5.0638542476312 7.60225848555804e-07 ERI3 other 1.06731438986432e-18 0.0119211015312036 5.35503731323014e-05 6.07231403308169 -5.0638542476312 0.823477363559469 2.38263378121995 4.89266551443006 0.486980721284295 0.626665636206036 -0.705850248200211 8.52962685550872 -0.0827527698640591 0.934109214141889 PTCH2 other 1 1 1 0.486980721284295 -0.0827527698640591 7.80632466597105e-09 -19.0679095194187 137.818629836392 -0.138355094242736 0.890062157231685 -1310.29330281208 239.014283311925 -5.48207113255271 9.5955454389392e-08 AKR1A1 other 8.0085084748197e-05 0.00151648000116995 1 -0.138355094242736 -5.48207113255271 0.273272484968816 -316.954611615569 1813.06161032351 -0.174817342009141 0.861353216590756 -4602.15447367754 3144.33267771038 -1.46363471852117 0.144448445576628 PRDX1 other 1 1 1 -0.174817342009141 -1.46363471852117 3.21118161156203e-08 341.316093454022 67.4315497348657 5.06166764364817 7.66600698263578e-07 -28.3751511468251 118.491835861594 -0.239469250691407 0.810922087352723 PIK3R3 other 0.000317232631406213 1 0.00856676280309548 5.06166764364817 -0.239469250691407 0.0179774207190511 -289.215367150716 314.830778155378 -0.918637525991758 0.359099088072954 -1543.11627115268 553.225856977098 -2.78930612459888 0.00565531218955807 TSPAN1 other 1 1 1 -0.918637525991758 -2.78930612459888 4.82728664390501e-07 97.7186693719633 18.7754192073016 5.20460652798429 3.83542281624113e-07 -101.487230348353 64.2511229519114 -1.57954018055545 0.115374385900788 BLZF1 other 0.00441503636451552 1 0.00437314909507814 5.20460652798429 -1.57954018055545 0.613389604802744 2.20504709800432 3.70361132243011 0.5953775669304 0.552086144991789 10.4596741139513 12.6740811385457 0.825280665289439 0.409935471884092 CCDC181 other 1 1 1 0.5953775669304 0.825280665289439 0.00019019117578142 96.6955411233959 23.0057483728284 4.20310348337117 3.57471875264204e-05 31.3272583028786 78.727678513218 0.397919243835177 0.691001841107444 SLC19A2 other 1 1 0.350179449008814 4.20310348337117 0.397919243835177 8.24452975723463e-09 107.194350395672 30.2552349307682 3.54300175295153 0.000465416713783085 -136.388896443103 53.2297267012912 -2.56226933511185 0.0109380518587791 FAAH other 8.44322292438399e-05 1 1 3.54300175295153 -2.56226933511185 3.83725826780097e-20 113.469440497219 21.7495654736837 5.21708999816634 3.60782857216683e-07 -186.761870778449 38.2186966234915 -4.88666247879459 1.75414843313952e-06 NSUN4 essential 5.6181298298874e-16 0.0273506823695114 0.00412230492655782 5.21708999816634 -4.88666247879459 7.96352834812603e-06 206.309337054058 85.639739070306 2.40903743161441 0.0166595582395033 -325.66032813143 138.323359291086 -2.35434079826036 0.0192667799356137 TMED5 other 0.065778744155521 1 1 2.40903743161441 -2.35434079826036 2.18721615374557e-23 262.29994045593 71.540619140729 3.66644772726882 0.000295543057479155 -821.714716545979 115.546021085097 -7.11157951463173 1.00701638208707e-11 DR1 essential 3.31275758646304e-19 1.6064932343435e-07 1 3.66644772726882 -7.11157951463173 0.38977253651314 -5.69349381187633 16.7908071456678 -0.339083985807394 0.734810035471262 -75.0910613557744 55.662328789665 -1.34904634765689 0.178452342922884 FMO6P other 1 1 1 -0.339083985807394 -1.34904634765689 1.04013948525809e-07 362.674968219114 310.750824223215 1.16709253829236 0.244195138532174 -2120.44958395932 503.215931439432 -4.21379660594974 3.41944408949671e-05 CNN3 other 0.00099580525149011 0.518661279494861 1 1.16709253829236 -4.21379660594974 5.8844154963787e-05 1006.70852751547 231.243981679565 4.35344747224801 1.90378373089246e-05 -605.006315026136 758.815110280295 -0.797303989904281 0.425975095391745 PRRC2C other 0.447627486809528 1 0.191044697395058 4.35344747224801 -0.797303989904281 1.45307559293006e-05 2241.24254911666 504.274412094128 4.44448993517106 1.28218378598774e-05 653.285561604726 815.64443980582 0.800944050768314 0.423860543663746 F3 other 0.117437569420607 1 0.130526309413552 4.44448993517106 0.800944050768314 5.32059281134563e-10 117.608530051 49.7848645679723 2.36233504041025 0.0188620325910712 -332.484960154361 80.5251010114166 -4.1289604853426 4.84691748383541e-05 ABCD3 other 5.83669031404616e-06 0.731981478408824 1 2.36233504041025 -4.1289604853426 8.12468682875449e-07 114.303491212971 21.3831943010826 5.34548251320824 1.92080368050053e-07 -38.7542410788051 69.2520743465716 -0.559611267163778 0.576208550621023 VAMP4 other 0.00728325297429968 1 0.00223274219821381 5.34548251320824 -0.559611267163778 1.06506932591433e-11 130.670283960498 29.4331587620563 4.43956032775358 1.31332852213615e-05 -89.801618360006 42.3795811663052 -2.11898314916347 0.0350015278219072 DPH5 other 1.26210715120848e-07 1 0.133591777271689 4.43956032775358 -2.11898314916347 0.264330231032584 0.289738966520502 2.82064659132948 0.102720761761202 0.918260845031309 14.7839089114726 9.04392531880347 1.63467834931531 0.10328182167551 FASLG other 1 1 1 0.102720761761202 1.63467834931531 6.88645417363824e-10 82.1425709019453 25.463430450098 3.22590355855329 0.00140869052693156 -130.79976412242 41.3577120374791 -3.16264507098185 0.00173988502258168 PTBP2 other 7.51036692176986e-06 1 1 3.22590355855329 -3.16264507098185 0.502351549898333 -6.5127238454289 8.65702232081227 -0.752305308231875 0.452522824104921 -26.8415802701853 27.7572750848373 -0.967010637324694 0.334404088996775 TNFSF4 other 1 1 1 -0.752305308231875 -0.967010637324694 2.3888044196811e-10 1582.54409293939 228.410295131906 6.92851472402099 3.11546430718264e-11 741.936690673277 732.358905780238 1.01307799334103 0.311929890814965 PRDX6 other 2.66925005855167e-06 1 4.22488114697038e-07 6.92851472402099 1.01307799334103 3.69706161742644e-13 364.118319984116 45.7701260229443 7.9553707106156 4.99075012368515e-14 2.67121304971506 146.620390999049 0.0182185644951144 0.985477998283826 DARS2 other 4.6261332018857e-09 1 7.19217000324266e-10 7.9553707106156 0.0182185644951144 0.535091714939634 6.45021516591681 12.3070379030563 0.524107849242504 0.600636706130348 35.3828805768003 33.827656820982 1.04597491821703 0.296515080462308 HSD11B1 other 1 1 1 0.524107849242504 1.04597491821703 3.58780755947291e-05 1108.39372983167 380.094497253935 2.91610043775816 0.0038442520703879 -3333.31755553727 1044.74417921934 -3.19055862845584 0.00158893128271426 IRF6 other 0.278844403522235 1 1 2.91610043775816 -3.19055862845584 9.70497549666087e-10 188.375140830818 28.8843350686491 6.52170598295265 3.44541830310835e-10 -57.8360629196289 79.3927329956359 -0.728480564119239 0.466955517474531 DIEXF essential 1.04910785118904e-05 1 4.52245606466002e-06 6.52170598295265 -0.728480564119239 0.641174715908785 -4.27338909541514 9.45371111670576 -0.452032968075742 0.651605495489671 -14.2496254365214 15.162029780007 -0.939823074039289 0.348142170876234 PLPPR4 other 1 1 1 -0.452032968075742 -0.939823074039289 3.07139711551716e-10 96.8915785514265 46.4724997841444 2.08492288991272 0.0380088750066965 -281.374746520667 68.409062230313 -4.11312094256404 5.17610099273705e-05 RCAN3 other 3.41262933505111e-06 0.781021878794093 1 2.08492288991272 -4.11312094256404 1.95375787622465e-12 146.515827160577 40.481015544579 3.61937133220458 0.000352299890840127 -204.171351875831 59.4523550619082 -3.43420124675004 0.000687360441837329 SYF2 essential 2.38182622690547e-08 1 1 3.61937133220458 -3.43420124675004 0.000178921026047561 14.3788366174274 83.5989891003763 0.17199773313243 0.863569118025345 -409.458708460513 123.656531722501 -3.3112582308178 0.00105633992512008 RSRP1 other 1 1 1 0.17199773313243 -3.3112582308178 4.64710450790713e-05 201.539136910045 63.4716044630865 3.17526457090359 0.0016692068874674 -96.7647478169556 101.645790136226 -0.951979887088992 0.341952350701951 SLC35A3 other 0.356897626207268 1 1 3.17526457090359 -0.951979887088992 1.10476405526452e-10 175.07711227353 26.6484290421101 6.56988492630734 2.55270216525732e-10 -130.842138081546 73.0410214222211 -1.79135142874303 0.0743485832969156 RCOR3 other 1.25412815553628e-06 1 3.3659930751083e-06 6.56988492630734 -1.79135142874303 2.31827967347971e-15 152.981536363764 45.6988895288128 3.34759855088623 0.000930629098400918 -307.305913836364 65.6136488401249 -4.68356689909366 4.46389108786521e-06 MTFR1L other 3.09374422425868e-11 0.0691679924064714 1 3.34759855088623 -4.68356689909366 0.00836873533353285 90.1738392397494 31.7311241311296 2.84181042143682 0.00482668058563615 26.4645220835478 45.5589809185553 0.580884856288988 0.56180081882871 MAN1C1 other 1 1 1 2.84181042143682 0.580884856288988 2.14947525454362e-07 162.481077117974 30.2287244416381 5.37505568359896 1.64789729670971e-07 -102.584654283087 82.8542990665267 -1.23813314986489 0.216734271649007 NEK2 other 0.00201577789371101 1 0.0019244144630976 5.37505568359896 -1.23813314986489 3.84375682854797e-12 184.32524238179 97.0370752244535 1.89953419304356 0.0585559319249642 -687.028950580469 139.653713644713 -4.91951794657113 1.50712003026485e-06 RPS6KA1 other 4.6317269784003e-08 0.0235216223123436 1 1.89953419304356 -4.91951794657113 6.03469160789366e-22 110.201238146755 34.9743983922068 3.15091161571805 0.00181010107827305 -334.535941162601 50.3344170943282 -6.64626632182251 1.64611178989716e-10 DHDDS essential 9.02729517624813e-18 2.62373758191708e-06 1 3.15091161571805 -6.64626632182251 1.333345324852e-05 330.933988809056 70.6738475738141 4.68255231842893 4.47719099536057e-06 -100.992577827059 192.769798453853 -0.523902492180254 0.600772978164258 NENF other 0.108054305126006 1 0.0472612281470262 4.68255231842893 -0.523902492180254 8.72821421398651e-07 178.09951352079 35.8783624870054 4.96398110658741 1.22020286461152e-06 -140.500032688325 97.8617259835861 -1.4356995166005 0.152236848639171 NSL1 essential 0.00780826043583234 1 0.0134485682250022 4.96398110658741 -1.4356995166005 0.276973889278902 -39.0853664521003 50.7380694570712 -0.770336098127855 0.441769101127126 -209.070465994022 138.58089198746 -1.50865291019299 0.132548160168091 PROX1 other 1 1 1 -0.770336098127855 -1.50865291019299 1.72602193373641e-10 807.980113273287 210.300624477906 3.84202431770796 0.000152038970346585 -767.974402402253 303.851690939653 -2.52746463258873 0.0120579144939135 ARID1A other 1.94091166448659e-06 1 1 3.84202431770796 -2.52746463258873 0.00391743733048255 412.71856832216 137.674936799238 2.99777561491821 0.00297098815076775 -396.514818136651 374.554005168406 -1.05863189998027 0.290706667643354 CENPF other 1 1 1 2.99777561491821 -1.05863189998027 6.70388325973761e-17 148.334154860341 62.0743583515525 2.38962042942537 0.0175496186294199 -549.967371657929 90.6304606733963 -6.06823983428528 4.34083257803704e-09 RPA2 essential 9.29493413962619e-13 6.90409421536792e-05 1 2.38962042942537 -6.06823983428528 8.92450921883559e-22 180.7239392352 46.6836608544296 3.87124608326539 0.00013587138429802 -421.217964388213 68.2527123945972 -6.17144652000022 2.46824872716205e-09 PPP1R8 essential 1.33242922637215e-17 3.92772419953298e-05 1 3.87124608326539 -6.17144652000022 0.00895418612094892 54.6490309062332 84.1686464919939 0.649280143900512 0.51670924743251 -263.68968404275 123.056725126463 -2.14283033919325 0.0330207567325852 STX12 other 1 1 1 0.649280143900512 -2.14283033919325 0.942730763636046 5.83259095320858 19.0874930241948 0.305571346945109 0.760164762250948 10.1395898186804 53.0280193840672 0.191211927891219 0.848502210406801 MARC2 other 1 1 1 0.305571346945109 0.191211927891219 0.829009118914873 3.90744386793733 7.13152410291481 0.547911471874613 0.584208745032103 0.712487720428929 12.216468897862 0.0583219035210429 0.953535682656822 SLC5A9 other 1 1 1 0.547911471874613 0.0583219035210429 1.52491614701388e-13 278.044267327778 71.8511613916113 3.86972544274337 0.000136787753170343 -434.922073003481 115.244457487568 -3.77390880642046 0.000197734384271928 OSBPL9 other 1.93252623311069e-09 1 1 3.86972544274337 -3.77390880642046 1.76953066100074e-12 271.899941422639 86.476314541356 3.14421287337132 0.00185196038793676 -568.787280268928 139.174112698149 -4.08687556357954 5.7764027673639e-05 TXNDC12 other 2.1611277962802e-08 0.869810728709656 1 3.14421287337132 -4.08687556357954 3.8760339899185e-13 506.192295873947 94.5110123405982 5.35590809301391 1.86860151415983e-07 -683.747950061743 242.709040695295 -2.81715072542413 0.00521554493882581 ESYT2 other 4.84620529759509e-09 1 0.00217411786172496 5.35590809301391 -2.81715072542413 4.99801440087211e-18 163.158499571623 22.7319035817659 7.17751150864894 6.72128715891343e-12 -217.097397034062 63.8646531596935 -3.39933572474293 0.000776334335750087 CD3EAP other 7.08568501611639e-14 1 9.28276969517534e-08 7.17751150864894 -3.39933572474293 8.49988869224048e-09 870.047935278338 168.491952270028 5.16373585537182 4.69300868018211e-07 -473.824333877876 329.025624496152 -1.44008338135809 0.150998026036903 RCN2 other 8.69793609876969e-05 1 0.00531717883464633 5.16373585537182 -1.44008338135809 0.151002179025219 15.4585930751873 7.96379617433172 1.94110857897295 0.0532741723647705 7.59866284558781 15.432288730067 0.492387291250145 0.622841321795715 CHRNB4 other 1 1 1 1.94110857897295 0.492387291250145 0.650723247742868 -318.349962926279 574.763250548917 -0.553880163044949 0.580117583217108 140.062147047235 888.365679116569 0.157662717436944 0.874839988982799 MUC5B other 1 1 1 -0.553880163044949 0.157662717436944 6.21207184234008e-06 -3454.83950655891 2125.07702145346 -1.62574790074947 0.10515708085013 -14421.0437780453 3133.14524210286 -4.60273707846572 6.39466801627606e-06 CTSD other 0.0517092860156389 0.0987336741713024 1 -1.62574790074947 -4.60273707846572 0.119446600400854 13.7327808524818 13.8558930123573 0.991114815929533 0.322526852509195 -55.6695239023483 40.545145201398 -1.37302563909498 0.170896376739374 COLEC11 other 1 1 1 0.991114815929533 -1.37302563909498 1.04083769428578e-08 143.508858429986 25.9064150997884 5.53951049873967 7.21877570534895e-08 -274.503786754706 132.254724914616 -2.07556884589134 0.0388840026704624 STAG1 other 0.000105946868901349 1 0.000859683998750006 5.53951049873967 -2.07556884589134 2.1180197207815e-14 103.285231627857 58.0939871684298 1.77789882674787 0.0765459051365015 -597.514191184473 101.39516719738 -5.8929257448861 1.12734485990517e-08 STK11 ts 2.75342563701595e-10 0.000179090004444536 1 1.77789882674787 -5.8929257448861 1.49876234577676e-07 389.017367243613 82.0891773621851 4.73896047864181 3.47813997827e-06 -57.0383817485552 145.720928222291 -0.391422031443182 0.695794035428603 KMT2A og 0.00141857856027771 1 0.037035234488619 4.73896047864181 -0.391422031443182 0.050844002084982 1.02398847307142 25.9549029652635 0.0394526026331853 0.96855859010246 -96.0854250925807 46.1308509684846 -2.0828886325601 0.0381989507665955 TREH other 1 1 1 0.0394526026331853 -2.0828886325601 3.72572659787167e-12 131.334086218311 28.836176263456 4.55449033944042 7.94442560887408e-06 -148.157455879271 51.251871428329 -2.89077162941173 0.00415415008453208 IFT46 other 4.49248113171365e-08 1 0.0822327494774556 4.55449033944042 -2.89077162941173 0.318771702832136 -3.47347041728124 2.83783142936545 -1.22398757774627 0.222019969969503 -7.85222463456364 6.20687039619991 -1.26508596657199 0.20692723591651 MMP8 other 1 1 1 -1.22398757774627 -1.26508596657199 0.783040722846847 -0.782464013359202 1.50156956168705 -0.521097412550162 0.602721339471816 -1.75146624796469 2.60511649439382 -0.672317822152606 0.501949997609658 APOA1 other 1 1 1 -0.521097412550162 -0.672317822152606 0.497112997222166 6.62785488470582 8.97951888750213 0.738108017561007 0.461082818148132 21.3947794253522 18.5673883437657 1.15227726319065 0.250215173065726 SLC8A2 other 1 1 1 0.738108017561007 1.15227726319065 1.86920064351071e-10 54.900268195598 14.6764866427395 3.74069554464912 0.000223653635503947 -113.050580091596 30.347285910508 -3.72522868848878 0.000237110192379337 KPTN other 2.09855156246947e-06 1 1 3.74069554464912 -3.72522868848878 2.72188783447425e-12 1469.87363267804 258.764879405274 5.68034439625767 3.46168327763741e-08 -681.501681036522 465.080891017013 -1.46534010362424 0.143987371206972 RPS25 essential 3.29811148903245e-08 1 0.000418655975597468 5.68034439625767 -1.46534010362424 1.59136290976957e-05 104.975989739527 23.2013856108958 4.52455691655885 9.03888140895391e-06 -68.1252664139271 64.0234727877186 -1.06406702803843 0.288238593020164 KIF14 other 0.128088800607352 1 0.0931275951564521 4.52455691655885 -1.06406702803843 0.365558146128302 3.51074010857776 17.5216163978912 0.200366223575143 0.841343354390645 68.535715155171 48.240684201632 1.42070362992183 0.15654406650358 TNNT2 other 1 1 1 0.200366223575143 1.42070362992183 1.29972848923729e-14 127.54081241316 15.8438845130507 8.0498448665227 2.56888664619852e-14 -76.5351468790614 43.7206865997128 -1.75054768878136 0.0811471457993818 DDX59 essential 1.69899571213836e-10 1 3.72000475236007e-10 8.0498448665227 -1.75054768878136 2.27401483386703e-06 336.17095129419 65.0500960718574 5.16787786020854 4.57835687038718e-07 -26.5324380567972 179.503635064762 -0.147810032076648 0.882601800842805 CAMSAP2 other 0.0196474881646112 1 0.00519185669101906 5.16787786020854 -0.147810032076648 3.28991040879941e-09 280.994924549962 43.37800259592 6.47782073249245 4.31878683847172e-10 34.5895306748063 152.017752559812 0.227536127145394 0.820177190344896 ATF6 other 3.44716812634002e-05 1 5.65329197155948e-06 6.47782073249245 0.227536127145394 0.0158123990191753 9.68157563862732 60.8780656406373 0.159032248097001 0.873761052558767 -215.172759054249 91.5717660307315 -2.3497718607069 0.0194973531450049 MREG other 1 1 1 0.159032248097001 -2.3497718607069 1.67854877003284e-16 165.51816474263 29.6606729382934 5.58039141886555 5.85112337083216e-08 -202.502547327101 51.5115209809849 -3.93120885329426 0.000107568556010393 FASTKD2 other 2.30347247711607e-12 1 0.000700437978722318 5.58039141886555 -3.93120885329426 0.324121863351864 -183.77567391571 202.979127116483 -0.905391980576642 0.366067965353844 -586.192509146505 404.980940583819 -1.44745702921587 0.148933353415695 NRP2 other 1 1 1 -0.905391980576642 -1.44745702921587 4.14922629952598e-10 112.9091580996 36.3473182529319 3.1063958367958 0.00209647275419449 -252.761798629618 63.1326915037066 -4.00365947671941 8.07308901935186e-05 CREB1 other 4.57825629889697e-06 1 1 3.1063958367958 -4.00365947671941 0.00386090702801718 -11.3257286368521 75.0705265731289 -0.150867845929112 0.880193036067952 -400.34493383703 130.374553964783 -3.0707290775865 0.00235403718355514 KLF7 other 1 1 1 -0.150867845929112 -3.0707290775865 9.6624885076646e-10 98.2935459214967 21.3670770051195 4.60023361632225 6.53583695524711e-06 -100.535604533173 41.1872578290385 -2.44093950003857 0.0153017262863886 B4GALT6 other 1.04461163256362e-05 1 0.0681622436062721 4.60023361632225 -2.44093950003857 1.11362744675571e-08 64.4539918858482 10.3167489577371 6.24750996170266 1.67025170251767e-09 24.2046841068555 35.0188798862111 0.691189557904341 0.490056058915494 C1orf54 other 0.000113122276041445 1 2.14076160711689e-05 6.24750996170266 0.691189557904341 0.191561461152072 -0.510266514192496 1.7180775705823 -0.296998530758744 0.766702061596132 -10.5377352797031 5.83179374877526 -1.80694581009764 0.0719135023746327 CA14 other 1 1 1 -0.296998530758744 -1.80694581009764 0.903751548579083 -0.00508004156965415 2.5201573680009 -0.00201576363212741 0.998393165302313 6.67758411359707 15.1241488878215 0.441518009583606 0.659196717787436 CASC1 other 1 1 1 -0.00201576363212741 0.441518009583606 0.525506721479325 -18.5181929691326 51.2279112435368 -0.36148639520158 0.718022835539914 -346.023601520889 307.43260984291 -1.12552666972348 0.261380418600427 LRMP other 1 1 1 -0.36148639520158 -1.12552666972348 0.00594075261345632 -48.9176497802456 44.7895969214872 -1.09216543890749 0.275723271611738 -233.475775567379 73.1622659484065 -3.19120481768599 0.00158232508642491 ATP10B other 1 1 1 -1.09216543890749 -3.19120481768599 6.81628245875812e-19 285.888279852215 33.5891173218846 8.51133648772451 1.17622749720178e-15 -126.937413851556 87.0590115287636 -1.45806174022108 0.145977177179213 SPCS2 essential 9.80726720166119e-15 1 1.73434744462402e-11 8.51133648772451 -1.45806174022108 0.00592374385342975 24.2740527008658 15.7340895700266 1.54276817815425 0.124058230791353 -80.0386767423713 39.6000147306131 -2.02117795376719 0.0442480347378449 USP35 other 1 1 1 1.54276817815425 -2.02117795376719 7.61516526103366e-07 80.1718349049314 17.4653751017804 4.59032997789774 6.80876672136994e-06 -52.7116787756994 40.5902336172161 -1.29862959826233 0.19518736123104 ELOVL4 other 0.00684603356966926 1 0.0708656440360183 4.59032997789774 -1.29862959826233 0.849254137265024 -16.4199784986116 32.3049376992258 -0.508280766596404 0.611677714397546 6.40126501548548 74.5499187288359 0.0858654861686586 0.931637943389097 FILIP1 other 1 1 1 -0.508280766596404 0.0858654861686586 4.07231845260522e-14 186.48656076787 24.9388675079246 7.47774776495412 1.05248187148741e-12 -86.6855821789962 58.1285913759792 -1.49127271325583 0.137052988145835 CASP8AP2 other 5.25654865862282e-10 1 1.48189447505428e-08 7.47774776495412 -1.49127271325583 3.85118121269035e-07 378.054289689288 89.4021176443121 4.22869502032809 3.22822846710603e-05 -434.512559901066 207.774114206488 -2.09127379298676 0.0374451428445194 HMGN3 other 0.00354924860561542 1 0.317431705170535 4.22869502032809 -2.09127379298676 1.35225437948373e-12 35.0994214927672 4.72507830158406 7.42832589271596 1.42441209162293e-12 0.876818574716385 11.324617301203 0.0774258901113809 0.938341668558922 UBE3D other 1.657999094685e-08 1 2.00030190026608e-08 7.42832589271596 0.0774258901113809 0.534221987662197 20.1495812899883 22.3209140865958 0.902722048560211 0.367472150595202 50.7688485106508 56.1318806346486 0.904456575062846 0.366553730139882 CNR1 other 1 1 1 0.902722048560211 0.904456575062846 4.21005516262301e-11 77.1463226484865 18.8115875197653 4.10100011854019 5.44349149803911e-05 -75.7702183225448 29.5080550050734 -2.56778084185886 0.010771800285355 ANKRD13C other 4.86977080660604e-07 1 0.524044926516225 4.10100011854019 -2.56778084185886 0.44992000444742 -11.331355718253 10.5496330816585 -1.07409950948471 0.283733516008401 -0.558618948541458 16.3144345445654 -0.0342407790484865 0.972710354807755 SGIP1 other 1 1 1 -1.07409950948471 -0.0342407790484865 4.15958521601397e-11 430.030352912105 74.4390723978865 5.77694400346014 2.36822763935427e-08 -427.796584979434 152.961680397104 -2.79675657242279 0.0055837527314776 PHF3 other 4.81305605344976e-07 1 0.000288592220131711 5.77694400346014 -2.79675657242279 0.0101505270227609 62.2755017556325 41.3504747998311 1.50604079051317 0.133212869278884 -145.598439741505 72.9610408294594 -1.99556418173679 0.0469749528609937 PLAGL1 other 1 1 1 1.50604079051317 -1.99556418173679 0.00028113996153885 117.018396762421 38.5023601291942 3.03925256451208 0.00260345539122673 -107.467738401127 67.7827246286834 -1.58547386505691 0.114024865287173 FBXO30 other 1 1 1 3.03925256451208 -1.58547386505691 0.226060460180837 -57.1982907300265 295.163341884725 -0.193785211824729 0.846489237946131 -915.114234792536 539.503070094055 -1.69621691797416 0.0909931449113145 TNFAIP3 ts 1 1 1 -0.193785211824729 -1.69621691797416 1.8362037548332e-06 64.8158309092015 13.7265597893956 4.72192828382788 3.7520204531605e-06 -16.8318847183358 25.6396804845266 -0.656477943572415 0.512073694294712 AKAP7 other 0.0160245501684293 1 0.0398614652943772 4.72192828382788 -0.656477943572415 0.000349094938331292 183.681602040134 48.6340766913508 3.77680866043459 0.00019541686593981 -7.99700995567892 85.8935911252603 -0.093103686211195 0.925890236179983 RAB32 other 1 1 1 3.77680866043459 -0.093103686211195 0.0009392955519526 360.497836930195 109.895435172413 3.28037134904298 0.00117243007205343 -159.05373038861 201.147979200847 -0.790729944295356 0.429793036529246 MYB other 1 1 1 3.28037134904298 -0.790729944295356 0.0071756216852671 44.0102518007893 38.5478097162423 1.14170564098861 0.254584193343252 223.370297645484 70.556288483467 3.16584534768754 0.00172286695188483 ALDH8A1 other 1 1 1 1.14170564098861 3.16584534768754 0.170828150010666 858.70503073616 714.89159566063 1.20116817143812 0.230734720064683 -1314.49891460354 1308.09310984574 -1.00489705565268 0.315842834086614 SGK1 other 1 1 1 1.20116817143812 -1.00489705565268 1.17212149435607e-06 69.5020940681097 21.3722309172677 3.2519812431914 0.00129055880245644 -116.761575671976 39.7932513979791 -2.93420546374118 0.00362924952709858 RNF146 other 0.0103873406829835 1 1 3.2519812431914 -2.93420546374118 0.0264365632205785 8.57148367438317 3.19021143114087 2.68680739800304 0.00765971974841678 7.39763008287059 5.95895861945887 1.24143001408229 0.215520374985689 ARG1 other 1 1 1 2.68680739800304 1.24143001408229 0.456891801371447 77.951204846451 358.948731773259 0.217165288372411 0.828242940063764 -748.292531339286 678.773147186639 -1.10241917265111 0.271257543845891 CTGF other 1 1 1 0.217165288372411 -1.10241917265111 0.411864454598292 8.02165311115046 62.6648057502928 0.128008904122598 0.898236866268952 -139.967024629086 114.502198745982 -1.22239595537895 0.222620012731775 TCF21 other 1 1 1 0.128008904122598 -1.22239595537895 1.96021751915504e-08 29.1103280081659 11.360669654615 2.56237782570683 0.010942843316076 -63.8239276389165 19.6152240986094 -3.25379548650893 0.00128487948691135 PMFBP1 other 0.000196158967141844 1 1 2.56237782570683 -3.25379548650893 1.98396121988327e-06 10.1463447743399 145.103759146194 0.0699247547688773 0.94430550303962 -826.527300185381 212.568175336133 -3.88829277420478 0.000127253101296447 FBXL5 other 0.0172564946905447 1 1 0.0699247547688773 -3.88829277420478 1.66413023840605e-19 422.729175250314 79.9627348302416 5.28657725561482 2.57429671832307e-07 -337.905303368862 115.125530094172 -2.93510312692985 0.00362124614057282 MED28 essential 2.41565145407022e-15 1 0.00297176813163215 5.28657725561482 -2.93510312692985 0.768396510256279 -16.178487930515 24.0943231470388 -0.671464719377409 0.502496482156938 2.22451278656804 63.3098094937887 0.0351369369826691 0.971996414830945 SLC16A7 other 1 1 1 -0.671464719377409 0.0351369369826691 2.25166689608901e-13 187.597659546146 25.665981276664 7.30919490371145 3.02332697749076e-12 -77.5174833754852 75.6718500447175 -1.0243899591417 0.306564649506248 TMEM5 other 2.83890162258903e-09 1 4.21451780662212e-08 7.30919490371145 -1.0243899591417 2.77149436929183e-17 52.823276755098 10.2480559707826 5.15446801868551 4.94339287197705e-07 -107.052267556001 22.7236629199748 -4.71104803538953 3.96168980058051e-06 ZNF430 other 3.87482627770691e-13 0.0614458088070038 0.00558850564177006 5.15446801868551 -4.71104803538953 0.198485629948788 179.853608554627 131.141907659008 1.3714426743149 0.171392763295315 -563.607204220081 557.555650314356 -1.01085372178062 0.313005058826681 VAMP8 other 1 1 1 1.3714426743149 -1.01085372178062 1.17759331772375e-16 95.1152188076817 20.3682151630842 4.6697866281416 4.73504954489354e-06 -90.8802235489164 29.9368550164153 -3.03573049002923 0.00263127861697722 DCLRE1B essential 1.6215459985056e-12 1 0.0499121572527228 4.6697866281416 -3.03573049002923 3.81772981382426e-09 1826.63640203066 405.803964386314 4.50127786403722 1.01547382984171e-05 -2190.69941131349 876.541611045599 -2.49925318285834 0.0130557220539561 MYL12B other 3.98570992563253e-05 1 0.104218671361938 4.50127786403722 -2.49925318285834 7.91577925865826e-10 388.381284630122 90.691205363339 4.28245807379159 2.57465367309166e-05 -494.451914044881 158.140389792858 -3.12666431828418 0.00196194820298283 FOXO3 other 8.60845081292176e-06 1 0.255637363201271 4.28245807379159 -3.12666431828418 3.28301712957273e-06 20.4658400610773 5.78640761572892 3.5368818479787 0.000476678160578311 -20.890135354898 10.0898951798654 -2.07040162286173 0.0393688319826025 ARMC2 other 0.0279877210296075 1 1 3.5368818479787 -2.07040162286173 0.740731796271601 -43.9227257456101 62.826693749584 -0.699109297724281 0.485085521852444 -120.895591193444 240.457714233624 -0.502772770583622 0.61553388734062 GHRH other 1 1 1 -0.699109297724281 -0.502772770583622 3.79312473379622e-21 2928.3337006075 301.443153915359 9.71438117791765 2.56935864948653e-19 -1890.89595037528 1153.89316139061 -1.63870972950085 0.102442760498154 RPN2 essential 5.62520398021979e-17 1 3.91801500460202e-15 9.71438117791765 -1.63870972950085 9.03000625952659e-08 333.188492391202 57.8436460792072 5.76015716462542 2.29228709541248e-08 73.7339291023212 240.498749206125 0.306587578295992 0.75939448481805 TGIF2 other 0.000866790300851957 1 0.000279498565543643 5.76015716462542 0.306587578295992 0.348202738584854 2.19949886539263 16.0371943083191 0.137149854463737 0.89101418483283 -23.6619915005688 23.4155019554475 -1.010526767506 0.313144373044624 CASQ2 other 1 1 1 0.137149854463737 -1.010526767506 3.32747883621226e-08 39.6946338775227 41.6551131094715 0.952935448121421 0.341468831871812 -264.67454457783 64.7604731380568 -4.08697669662783 5.75699481109939e-05 PKD2 other 0.000328355611557426 0.867003418551568 1 0.952935448121421 -4.08697669662783 0.382399608066405 29.168974305986 26.6904201861291 1.09286306107481 0.275420898537949 0.422398191461933 41.4951277401343 0.0101794647821601 0.991885564528707 ABCG2 other 1 1 1 1.09286306107481 0.0101794647821601 0.941613898500107 -350.384781934792 4620.55227055212 -0.0758317970273549 0.939608663171476 1560.71567237092 7173.71472588933 0.217560320141868 0.827934817290325 SPP1 other 1 1 1 -0.0758317970273549 0.217560320141868 0.00127678870309621 12.2944939115006 30.8727996564844 0.398230612328619 0.690774914598176 -139.860080487303 50.4861206163919 -2.77026792274257 0.00598978479178034 STBD1 other 1 1 1 0.398230612328619 -2.77026792274257 7.64737258407175e-19 1349.16780002764 351.477137066124 3.83856489582656 0.000154083919384544 -3046.64257492054 582.288906306057 -5.23218378699317 3.3581633992491e-07 CCNI other 1.09938628268615e-14 0.00528373429237853 1 3.83856489582656 -5.23218378699317 0.543051901508999 46.2114229972767 86.2696462354247 0.535662599927308 0.592653212757085 583.68964324868 584.544199024207 0.998538081847441 0.318954099564202 RARRES1 other 1 1 1 0.535662599927308 0.998538081847441 4.96735306052035e-05 185.434902852733 40.8713487607857 4.53703898880503 8.74955576890748e-06 115.252568277894 278.097950700229 0.414431562647971 0.678902435912348 MFSD1 other 0.380399897374648 1 0.0902691668678185 4.53703898880503 0.414431562647971 1.04778690083124e-09 200.872784853806 32.0137770539455 6.27457311629681 1.38247378328018e-09 -138.062488018465 89.989434272745 -1.53420775599074 0.126145152481681 RAB3GAP2 other 1.13003817254649e-05 1 1.77786128529831e-05 6.27457311629681 -1.53420775599074 4.2785960992845e-25 151.783707381307 18.1005618541496 8.38557988444488 2.76021978597138e-15 -104.808758962031 35.4151842270042 -2.95943000861518 0.00335354141472329 EEF2KMT other 6.55652066254356e-21 1 4.05338275569896e-11 8.38557988444488 -2.95943000861518 2.51397795419739e-09 989.479805440963 315.445073771177 3.13677368174317 0.00189501146874217 -2082.3649793734 617.511314789087 -3.37218918828173 0.000853612311746717 PPL other 2.65652050420038e-05 1 1 3.13677368174317 -3.37218918828173 7.78020308954343e-21 503.768229457019 67.3596550885548 7.47878279356888 1.02794208640985e-12 -344.281302263353 131.862414841977 -2.61091306932258 0.00952920174988462 UBN1 other 1.14960280851094e-16 1 1.44806201712555e-08 7.47878279356888 -2.61091306932258 7.23900814610679e-08 89.3602276848364 23.0934181864479 3.86951065292172 0.000139069286835763 -110.383305214361 46.7671620461456 -2.36027375587693 0.0190270838985196 KLF12 other 0.000699360576995377 1 1 3.86951065292172 -2.36027375587693 3.63966701127276e-12 165.33253181123 28.8963616001632 5.72156917534894 2.99598785068325e-08 -122.442612068557 58.5188738448387 -2.0923610456553 0.0374108967174306 UCHL3 other 4.39125824910059e-08 1 0.000363383366409372 5.72156917534894 -2.0923610456553 0.520533187096111 36.1493483988885 70.2180122953007 0.514815888647817 0.607117374511047 135.321950293161 118.35402597142 1.1433658397547 0.253934358651745 PCDH17 other 1 1 1 0.514815888647817 1.1433658397547 2.38394233669048e-10 170.017926346961 27.5039215998159 6.18158853201859 2.33324305282034e-09 -158.40991882891 89.988511894423 -1.76033490824652 0.0794832533295605 HS1BP3 other 2.66405556125161e-06 1 2.97301829790368e-05 6.18158853201859 -1.76033490824652 5.08829465459542e-06 106.165093308424 22.0644521857425 4.81158981037495 2.49368891680332e-06 -34.1366439629891 72.1914222579048 -0.472862881701312 0.636693034249353 LDAH other 0.0427264102146378 1 0.0268744854563894 4.81158981037495 -0.472862881701312 0.00209604507386794 51.4384244769092 15.7180626757915 3.27256771638486 0.00120506478195885 -33.5921534095576 51.4269406600695 -0.653201473360057 0.514184300792961 WDR35 other 1 1 1 3.27256771638486 -0.653201473360057 4.24471040412103e-06 1107.40691414561 239.268621211565 4.6282998102222 5.71351944360281e-06 -1351.96513699136 1105.40097418521 -1.22305404876985 0.22236786732497 CCND2 og 0.0358975158876516 1 0.059826262093965 4.6282998102222 -1.22305404876985 2.60783093274629e-08 656.240360228167 164.754243034428 3.98314694748733 8.72890229588375e-05 -598.34868862177 286.904124699834 -2.08553533082794 0.0379494205373884 ELL2 other 0.000259166238096326 1 0.823135486501837 3.98314694748733 -2.08553533082794 0.745491155500213 -1.44085386879433 9.68643005266981 -0.148749731424241 0.881861338552038 -18.4647202480657 24.1583512009594 -0.764320383227664 0.445338884119437 DNAH7 other 1 1 1 -0.148749731424241 -0.764320383227664 4.40142230717402e-17 86.0907950315757 10.1490854379066 8.48261605031214 1.50826786659487e-15 -26.7590539215323 22.9559762842756 -1.16566830311032 0.244784955597003 CYP20A1 other 6.12854042050911e-13 1 2.2210752603476e-11 8.48261605031214 -1.16566830311032 8.03168599248145e-09 191.633864818885 32.2489754435903 5.94232412605138 8.88392313872333e-09 -0.271295640907807 72.0895319373124 -0.00376331533326808 0.997000168812121 NDUFB3 other 8.23247814229349e-05 1 0.000110560423461412 5.94232412605138 -0.00376331533326808 1.73251903837363e-19 407.015811382263 42.2248756929759 9.63924238265952 4.34148103665659e-19 -26.81030734905 105.257254152527 -0.254712205490364 0.799139283196459 GTF3C3 other 2.51388512468014e-15 1 6.61207561882798e-15 9.63924238265952 -0.254712205490364 0.0957448857834821 69.5964658103937 37.0240826927808 1.87976205617011 0.06122530485705 -43.7069045990478 86.7226670981631 -0.503984783465839 0.614686119685911 SATB2 other 1 1 1 1.87976205617011 -0.503984783465839 9.85437824068774e-12 235.383408844208 70.6373125176308 3.33228148771171 0.000980322781964382 -472.243983511679 113.177038943967 -4.17261299569326 4.05105455884123e-05 UBE2B other 1.16892634691038e-07 0.61341068129974 1 3.33228148771171 -4.17261299569326 0.0202864041973833 14.5563439949163 8.29314325655963 1.7552264014495 0.0803422186901064 -17.2641785923539 15.6607094008448 -1.10238803048236 0.271263894216683 TRPM6 other 1 1 1 1.7552264014495 -1.10238803048236 0.00832491975874799 104.318533438166 85.9155912294104 1.21419793480343 0.225737016973399 -318.136189385337 162.520715394073 -1.95751162314253 0.0513212282389719 GDA other 1 1 1 1.21419793480343 -1.95751162314253 0.0302175170118572 -55.7710805787351 94.3493201968064 -0.591112691245685 0.554944990957956 -458.500237250724 178.483109240013 -2.56887186245821 0.0107468781876745 KLF9 other 1 1 1 -0.591112691245685 -2.56887186245821 7.15086319891062e-10 124.413489100726 71.1817867952564 1.74782756519701 0.0816477215339836 -675.291597226853 137.707460954862 -4.90381270952486 1.63794313685145e-06 TJP2 other 7.79301071417279e-06 0.0255502749917458 1 1.74782756519701 -4.90381270952486 0.288254330382055 -5.06724960254375 10.9125455149137 -0.46435083323305 0.642767854305204 52.3266693163752 38.3416965702522 1.364745798885 0.173460855504155 C2orf40 other 1 1 1 -0.46435083323305 1.364745798885 1.31942395075747e-12 361.533234935985 52.4261513951204 6.89604758913574 3.75985251501045e-11 -187.773747896141 157.782167017989 -1.19008219651802 0.235055592727568 ITGB1BP1 other 1.61827347560404e-08 1 5.08783242331214e-07 6.89604758913574 -1.19008219651802 2.28951486054938e-17 335.032693730763 38.8755559583601 8.61808109161496 5.75030517477871e-16 -92.3166363853627 117.370976119775 -0.786537178417561 0.432240091288139 CPSF3 essential 3.20783927111573e-13 1 8.51447687229483e-12 8.61808109161496 -0.786537178417561 1.56919481574732e-05 34.0330865138387 7.08641745366776 4.80257996884222 2.6327048332477e-06 32.8699782858508 51.3595461940016 0.639997443935549 0.522731395848775 PIGZ other 0.126398642408446 1 0.0283279040057452 4.80257996884222 0.639997443935549 3.53536529583889e-22 262.320286237418 24.221753619 10.8299461039703 7.63466117366345e-23 -80.4386034392962 175.54967401065 -0.458209927717759 0.647180000900779 SENP5 other 5.30092672458083e-18 1 1.18383056158826e-18 10.8299461039703 -0.458209927717759 0.0406967832572507 -47.2911948795758 45.3818449489271 -1.04207299048325 0.298303160910442 -235.457663562344 93.4861713414195 -2.51863628795356 0.0123550428344604 CCDC92 other 1 1 1 -1.04207299048325 -2.51863628795356 0.520643239591976 93.0283175709304 94.4294048192071 0.985162595793554 0.325419715434076 -122.403049610088 266.054537240122 -0.460067514276651 0.645835308001347 C1orf198 other 1 1 1 0.985162595793554 -0.460067514276651 1.02520478476208e-10 469.086951636462 69.1791831793906 6.78075296755179 7.37718921245772e-11 -257.22489084897 193.189887539157 -1.3314614658432 0.184147914513056 HEATR1 essential 1.16586288123144e-06 1 9.89576160959078e-07 6.78075296755179 -1.3314614658432 3.37728546972954e-14 562.433879703754 150.037658801409 3.74861807493407 0.000217666715889821 -1448.87756883347 291.014113922889 -4.97871924252233 1.14498709847743e-06 PTBP3 other 4.36818102654818e-10 0.017909888194384 1 3.74861807493407 -4.97871924252233 3.43103493072727e-30 1177.30602009783 143.159205944046 8.2237534941203 8.38295585737887e-15 -1560.07800403437 276.698055686997 -5.63819648157971 4.32535883243012e-08 RAD23B other 5.37711794343577e-26 0.000685223346233579 1.22265411179871e-10 8.2237534941203 -5.63819648157971 1.30581336783021e-11 246.773427737177 62.7213639008397 3.9344397568796 0.000105936954270527 -454.01953084549 118.565699467988 -3.82926540207415 0.000159587662410846 FKBP15 other 1.54307965676496e-07 1 0.991146144155052 3.9344397568796 -3.82926540207415 8.1860531150487e-18 507.557104552652 72.495821764514 7.00119113348814 1.99768584991428e-11 -371.518145537626 139.958041273479 -2.65449660596261 0.00841239974808297 CTNNAL1 other 1.15619814196948e-13 1 2.72544280503805e-07 7.00119113348814 -2.65449660596261 8.19355810907e-24 147.114862715658 18.922512432837 7.77459458609542 1.58279407087583e-13 -144.550997017467 36.5311780956909 -3.95692130811728 9.70268196033103e-05 FAM206A other 1.24533889699755e-19 1 2.26402863898078e-09 7.77459458609542 -3.95692130811728 4.69114469053036e-07 272.727242712329 81.247112940623 3.35676226319135 0.000901526727586684 -398.322123466387 151.415519311295 -2.63065586194951 0.00900973376205321 WDR34 other 0.0042952120786496 1 1 3.35676226319135 -2.63065586194951 4.82777527870346e-32 2171.35375510103 228.331567329625 9.50965204021227 1.08580945348685e-18 -2198.23815511689 425.528262987555 -5.1659039982056 4.64375722912602e-07 SET other 7.59215940328906e-28 0.00729859323701737 1.64967030268258e-14 9.50965204021227 -5.1659039982056 8.60324173148411e-20 731.167526206092 106.381343743622 6.87308037740335 4.34092831314134e-11 -792.149918690497 198.890837630701 -3.98283766173963 8.76302514605231e-05 PTPA other 1.25409454719844e-15 1 5.86502824388527e-07 6.87308037740335 -3.98283766173963 1.73202423555849e-29 384.793016530467 41.9931580795063 9.16323120547238 1.26744679047174e-17 -362.949518638756 78.1759675215826 -4.64272499778854 5.35599381325229e-06 GLE1 essential 2.70801989229571e-25 0.0828358003157599 1.90864812177139e-13 9.16323120547238 -4.64272499778854 4.00230448275754e-25 493.209847858551 87.0899439020607 5.66322385525019 3.78516974025035e-08 -1161.48150647048 167.465446382156 -6.93564870582307 2.96518406549608e-11 RAB14 other 6.1339318502742e-21 4.7285790292466e-07 0.000456756432556009 5.66322385525019 -6.93564870582307 3.11890969875746e-07 117.513720911469 31.4936242637136 3.73134955594382 0.000232020703661692 -134.051710670482 60.5591599811549 -2.21356621710401 0.0276915680143432 CNTRL other 0.0028946600914168 1 1 3.73134955594382 -2.21356621710401 1.29386592183333e-14 125.718054130691 21.0309694482657 5.97775839292364 7.10796364946938e-09 -111.506081777632 39.1029781193018 -2.85160075116096 0.00468476033355085 TRIM32 other 1.69147091961271e-10 1 8.8785573945522e-05 5.97775839292364 -2.85160075116096 3.29865324954977e-13 243.691459320604 56.9404253621186 4.2797618347742 2.59493483316161e-05 -469.071814923351 108.900439563565 -4.30734546897358 2.30985935387283e-05 FBXW2 other 4.13420211766073e-09 0.352161157091452 0.257599180887953 4.2797618347742 -4.30734546897358 3.63025620844781e-10 161.090080774545 31.984717196747 5.03647038001414 8.64818792167858e-07 -127.901542691805 61.1718254630274 -2.09085705263299 0.0374689310274116 PHF19 other 4.01905664837257e-06 1 0.00963434232354503 5.03647038001414 -2.09085705263299 0.250679085480111 70.1289925409379 43.5797734935172 1.60920966125191 0.108730476663409 24.1754660180271 83.5486726298373 0.289357870772365 0.772527961427529 NEK6 other 1 1 1 1.60920966125191 0.289357870772365 0.00624599115774679 53.7689694675802 31.087175340258 1.72961901102508 0.0848328150400831 -95.9259050917018 58.3998518738964 -1.64257103423543 0.10162724264653 BSPRY other 1 1 1 1.72961901102508 -1.64257103423543 1.10938123317545e-32 324.507393078564 40.4751118270102 8.01745513305812 3.18060798343557e-14 -552.897320745608 77.8469883802217 -7.10235979900901 1.06538263288409e-11 PPP6C other 1.74716450412802e-28 1.69949837597671e-07 4.59884108324949e-10 8.01745513305812 -7.10235979900901 1.00485635618495e-23 301.193962228379 39.7599219034209 7.57531574030746 5.62433831721563e-13 -339.601545917398 76.22546958375 -4.45522405794133 1.22544876786515e-05 NDUFA8 essential 1.52607534813808e-19 0.188228930744087 7.96687522633594e-09 7.57531574030746 -4.45522405794133 2.41929682725462e-11 92.9697482290765 28.9775935577117 3.20833226002422 0.00149488619266793 -241.115778738492 54.436826534086 -4.42927690848246 1.37127584202954e-05 HDHD3 other 2.82549676455067e-07 0.210394852442593 1 3.20833226002422 -4.42927690848246 3.11275198950842e-23 183.254921455558 25.5870778083145 7.16201055972126 7.44739453606684e-12 -234.346689202625 49.0540958795725 -4.77731135393758 2.9090433328889e-06 RBM18 other 4.70928248492729e-19 0.045221078609758 1.02744255019578e-07 7.16201055972126 -4.77731135393758 0.756213398117242 12.9276149464991 17.7244980323817 0.729364234907024 0.466406481192801 6.10336370634785 33.5056091932368 0.182159460857672 0.855593270349894 SLC46A2 other 1 1 1 0.729364234907024 0.182159460857672 5.24191254653833e-10 175.933077799648 42.5568367079028 4.1340731926858 4.76106584178477e-05 -238.066567018395 80.4325209421544 -2.95982973341851 0.00335138452450768 HSDL2 other 5.75247482857117e-06 1 0.460442677559005 4.1340731926858 -2.95982973341851 4.41942792552369e-25 420.316359792712 59.3635269306626 7.08038052192632 1.21830193778051e-11 -644.752637268868 114.17563985818 -5.64702451477154 4.09240465709399e-08 MAPKAP1 other 6.7714474674874e-21 0.000648400593869971 1.67224123979753e-07 7.08038052192632 -5.64702451477154 0.125498493305726 37.4510385756676 63.1540115512031 0.593011238016187 0.553671852621355 -187.14620352592 122.911627046131 -1.52260781199879 0.129031519122185 NR4A3 other 1 1 1 0.593011238016187 -1.52260781199879 2.85775077341088e-24 94.8270203956449 11.1180147203392 8.52913247381917 1.08497884001861e-15 -69.469110054695 21.489842174575 -3.23264868538147 0.00137937490457898 INVS other 4.35692682914223e-20 1 1.60077778056346e-11 8.52913247381917 -3.23264868538147 1.22835830815554e-06 54.0459594615011 24.096594674436 2.2428878516531 0.0257154757837169 -161.194678332698 46.8428345067419 -3.44118113325312 0.000670952820079769 GALNT12 other 0.0108636008773276 1 1 2.2428878516531 -3.44118113325312 1.35290927483543e-20 222.784354233816 30.6524671552503 7.26807252106154 3.87184592178019e-12 -215.719806517547 58.7651733442766 -3.67087841728552 0.000290895629940136 DENND1A other 1.99242948905014e-16 1 5.383027385051e-08 7.26807252106154 -3.67087841728552 1.30303541141484e-26 176.742243072694 23.0302477537716 7.67435265839679 3.04481356405851e-13 -240.03496211658 44.7698979359805 -5.3615257836822 1.77281301467935e-07 ALG2 essential 2.01214728230679e-22 0.00279625796805373 4.33916381013979e-09 7.67435265839679 -5.3615257836822 0.515333033518416 8.45018558300005 122.473350346727 0.068996116780322 0.945043970402742 -164.298790500045 173.005295409204 -0.94967492244347 0.34312987960613 CSF3R other 1 1 1 0.068996116780322 -0.94967492244347 8.64585454814893e-22 469.055429316045 64.494008634203 7.27285276957171 3.72991838088915e-12 -384.251145309455 114.4389440472 -3.3576956560432 0.000897751751847407 KDSR other 1.29117191822056e-17 1 5.18868945965489e-08 7.27285276957171 -3.3576956560432 8.10155722408241e-21 368.469673799498 65.9430396565835 5.58769622568818 5.56645585002595e-08 -582.663760405785 117.010122108614 -4.97960133624108 1.13107255200622e-06 VPS4B other 1.19676203314145e-16 0.0176956300761373 0.00066725106274261 5.58769622568818 -4.97960133624108 0.162408688649812 14.4739884393066 30.0330234966902 0.481935774495088 0.630241987777408 -66.4808698045691 50.5015003664517 -1.31641375646599 0.189151598311505 ONECUT2 other 1 1 1 0.481935774495088 -1.31641375646599 1.59258712357723e-16 87.5959555635718 23.6851858278926 3.69834360600268 0.000263053472675569 -205.757336078224 41.3231383293096 -4.97922820959328 1.14223444220986e-06 C19orf25 other 2.18741841423333e-12 0.0178679733794888 1 3.69834360600268 -4.97922820959328 1.11678754259803e-12 53.8246421480793 12.429563451417 4.33037269236862 2.12410972859183e-05 -131.680935536007 30.0438676210351 -4.38295552346966 1.69819668447265e-05 ZBTB45 other 1.3738720349041e-08 0.259993912392763 0.21221980298361 4.33037269236862 -4.38295552346966 6.40028076155748e-14 457.59809804386 71.4295361921593 6.40628684488209 6.53444266029991e-10 -234.691062170794 140.119253648407 -1.6749379978835 0.095095656419308 YLPM1 other 8.20708002054516e-10 1 8.49804267972003e-06 6.40628684488209 -1.6749379978835 3.18278500930702e-09 83.0136843147392 18.1459626453837 4.57477434165543 7.25172214956813e-06 -64.6429311763059 33.2677320382545 -1.94311205530852 0.0530342200448341 DCAF4 other 3.33905975326399e-05 1 0.0753598965783121 4.57477434165543 -1.94311205530852 4.73962721769591e-09 6.50947298850344 1.19430632399421 5.45042160267002 1.12690821428898e-07 -1.17692339596036 2.34280270692853 -0.502357024123183 0.615822852161279 PROX2 other 4.92020701469013e-05 1 0.00132918823875386 5.45042160267002 -0.502357024123183 2.09266369825656e-25 279.450744572985 29.7118547623208 9.40536182639703 2.21417920614481e-18 -123.874672886623 58.2105759891405 -2.12804410163769 0.0342292860596439 FCF1 essential 3.21307584230312e-21 1 3.35581000483307e-14 9.40536182639703 -2.12804410163769 1.53735513455385e-08 462.518419378777 76.3901459396844 6.05468694540745 4.65623758853327e-09 239.846880631824 150.637551269037 1.5922117600243 0.112498570885539 PGF other 0.000154734794292845 1 5.86266874772224e-05 6.05468694540745 1.5922117600243 2.05068771594323e-06 162.022597511159 33.0487545012256 4.90253263568982 1.62572858046758e-06 35.0252920800278 67.2652572561624 0.520704053009758 0.602995008330353 IFI27L2 other 0.0178040707498191 1 0.0177643361987693 4.90253263568982 0.520704053009758 0.000452514636681176 31.4212971405066 11.4267544336779 2.74980068250168 0.00636141386303809 -29.1559638863327 22.3284716143542 -1.30577517305705 0.1927282769583 BBOF1 other 1 1 1 2.74980068250168 -1.30577517305705 4.29523696607966e-15 437.350722389622 68.4008564550352 6.39393634898598 7.08005714389391e-10 -284.723562530943 128.531472961953 -2.21520500753325 0.0275806602324461 NEK9 other 5.69677278811145e-11 1 9.19557821848941e-06 6.39393634898598 -2.21520500753325 2.44819047041664e-07 47.3875908185831 9.90623777351869 4.78361128634115 2.83107367682378e-06 -9.01278233472815 18.6204841895362 -0.484025132912114 0.628758939993247 ACYP1 other 0.00228587544222802 1 0.0303774205523191 4.78361128634115 -0.484025132912114 1.15042900528585e-12 108.550516301939 16.4363707385049 6.60428740802499 2.10215566516914e-10 -20.7396011793656 30.5818484445194 -0.678167025024362 0.498244436911185 IFT43 other 1.4142223761979e-08 1 2.78115194501878e-06 6.60428740802499 -0.678167025024362 0.000590252832952338 43.0424132037947 17.1627041231009 2.50790393489682 0.012725563195207 -51.0994599488574 33.5368152052668 -1.52368254517002 0.128745563457767 DNAL1 other 1 1 1 2.50790393489682 -1.52368254517002 1.88391735153106e-07 183.15583646466 74.5457344023245 2.45695931407913 0.0146366031597282 -482.21614515444 139.791077021642 -3.44954882263183 0.000650663713185914 IRF2BPL other 0.00177238944432042 1 1 2.45695931407913 -3.44954882263183 6.40718477836172e-07 71.2052791813104 20.7505675697711 3.43148585897189 0.000693626440126489 -90.6906989413866 40.5997376698209 -2.23377549084018 0.0263109020755627 ACOT2 other 0.00579465791355034 1 1 3.43148585897189 -2.23377549084018 0.302258063506973 -284.066327465519 332.191911024503 -0.855127166069272 0.393230585496034 -1003.09186926406 650.820443030437 -1.54127283493637 0.124408695366383 LTBP2 other 1 1 1 -0.855127166069272 -1.54127283493637 1.40605323666039e-17 295.73921010518 39.4097620289903 7.5042120246154 8.75321439740332e-13 -131.239193905533 77.2104254565659 -1.69976001465451 0.0903150708881223 AREL1 other 1.97747327203917e-13 1 1.23446582646579e-08 7.5042120246154 -1.69976001465451 4.03549599383673e-13 93.1062305502339 14.9084220239817 6.24521028452662 1.62962118191157e-09 -41.0283131813885 28.0673788026712 -1.46177929438441 0.144960289723805 MLH3 other 5.04356289309715e-09 1 2.08933731732883e-05 6.24521028452662 -1.46177929438441 7.90119752360382e-16 161.718942015225 25.9050396900242 6.24275986257229 1.65965756478297e-09 -134.633366890684 48.5487880892497 -2.77315608050155 0.00593836260747003 TTLL5 other 1.0672937614884e-11 1 2.12751503229529e-05 6.24275986257229 -2.77315608050155 0.190586740351378 -21.7903170975645 23.641614757226 -0.921693265089027 0.357511426729545 -80.8148416213422 44.3068900364681 -1.82397910471318 0.0692605493494789 FLVCR2 other 1 1 1 -0.921693265089027 -1.82397910471318 2.35116091494853e-16 182.381725195178 26.2597312602893 6.94530052068661 2.76144474659075e-11 -104.023797659991 51.3128786873926 -2.02724540740976 0.0436088519859303 ABCD4 other 3.2161530155581e-12 1 3.75087039929422e-07 6.94530052068661 -2.02724540740976 3.72226020928037e-25 536.115668398177 63.9540043614354 8.38283190788688 2.81192750835057e-15 -443.867300964698 126.114101398138 -3.51956915240924 0.000506545743188339 DLST other 5.70659712684773e-21 1 4.12847196776031e-11 8.38283190788688 -3.51956915240924 0.000264775738784278 57.9704647141172 15.7020676846844 3.69190006553473 0.000268746963209324 0.112431720238366 32.4114231566938 0.00346889180690438 0.997234763777121 PPP4R4 other 1 1 1 3.69190006553473 0.00346889180690438 0.787143723636895 -33.5737662032276 57.3552284083168 -0.585365399719325 0.558787367150067 6.29950030863273 107.385083563116 0.0586627127307692 0.953263833275488 TGFB3 other 1 1 1 -0.585365399719325 0.0586627127307692 0.0115471571545383 8.66796690601015 5.15956120522112 1.67998140951187 0.0941132812301811 -13.9002045599476 9.69828607421351 -1.43326402764159 0.152935051933139 ZC2HC1C other 1 1 1 1.67998140951187 -1.43326402764159 3.56756930502617e-16 241.420710183868 32.5564378103869 7.41545225524778 1.53164462892414e-12 -72.3290292580912 61.348377867459 -1.17898845531589 0.239429279553481 SLIRP other 4.85938615037615e-12 1 2.14859108545479e-08 7.41545225524778 -1.17898845531589 0.000557851107726041 219.109882784565 104.178251004699 2.10322097627347 0.0363684031245768 -373.752177995769 190.710280201348 -1.95979040878745 0.0510450613391659 RBM25 essential 1 1 1 2.10322097627347 -1.95979040878745 9.54250298648068e-08 128.661816030635 28.5382904947871 4.50839254208785 9.70373264037294e-06 -70.8910356175074 55.7653017690649 -1.27123916429397 0.204725625312472 ALDH6A1 other 0.000915030611373632 1 0.0997349640777531 4.50839254208785 -1.27123916429397 0.91561701719217 6.24870373923656 26.5567155869302 0.235296556864578 0.814156271253011 23.6110828710883 56.9992864973203 0.414234709274795 0.679029897883317 GPR68 other 1 1 1 0.235296556864578 0.414234709274795 0.137117278345656 3.4417301078745 17.5760537480017 0.195819275317464 0.844897832166666 61.141109902707 32.9073051022024 1.85797985319117 0.0642522964975717 ESRRB other 1 1 1 0.195819275317464 1.85797985319117 1.2700609806918e-21 253.955269899614 27.9703698827913 9.07943909800991 2.32949256860952e-17 -44.5056223540774 52.6584883020005 -0.84517470571571 0.398758864217999 EIF2B2 essential 1.89289888562305e-17 1 3.49936373656521e-13 9.07943909800991 -0.84517470571571 2.54686988300054e-25 290.843489531093 26.9279163345181 10.8008167404423 7.71719686824563e-23 5.53849724139615 58.6264972424154 0.0944708877710186 0.924805177145592 NRDE2 essential 3.90766246148773e-21 1 1.19655137442148e-18 10.8008167404423 0.0944708877710186 4.34078621007979e-21 120.305865714492 15.1109034811357 7.96152697717121 4.59377214835523e-14 -75.6899413089298 29.5274901901593 -2.56337199069345 0.0109022143938938 COQ6 other 6.43304516333824e-17 1 6.62559756957275e-10 7.96152697717121 -2.56337199069345 1.37693998941777e-10 350.041880997918 57.5494622224458 6.08245268469933 3.98242232397079e-09 -40.3350638859091 112.454638026349 -0.358678526682538 0.720112814354429 ZNF410 other 1.55511602404843e-06 1 5.03179060633709e-05 6.08245268469933 -0.358678526682538 1.75884689854766e-06 300.057446675727 56.8543562063221 5.27765094352368 2.7041305638448e-07 133.503799961169 234.445254973618 0.569445519279934 0.569530802922027 RHOQ other 0.0153652865057124 1 0.00311759212705668 5.27765094352368 0.569445519279934 1.38278540429802e-10 17.1001761634797 2.44451786636395 6.99531649932875 2.08405117895241e-11 14.0257345101969 11.6726387279771 1.20159073171517 0.230575034717068 GPR75 other 1.56157955707375e-06 1 2.84160378250161e-07 6.99531649932875 1.20159073171517 1.64616446252134e-08 209.938612953622 34.7459485551711 6.04210337272192 4.96803114987231e-09 182.509554024176 129.96273626227 1.40432218706033 0.161359584938188 SUPT7L other 0.00016545599012802 1 6.24878958030939e-05 6.04210337272192 1.40432218706033 0.443443339711898 30.7886660343461 24.4833460858995 1.25753505776231 0.209646541579974 -2.97340396819877 82.2866520486651 -0.0361347058626261 0.971201649759148 KLHL29 other 1 1 1 1.25753505776231 -0.0361347058626261 2.13297008839606e-05 318.918093411353 67.5396286715581 4.72194028430681 3.74561392654927e-06 155.042256385742 244.348481460526 0.634512870548731 0.526279479765777 DNMT3A other 0.169699100232791 1 0.0397971479695859 4.72194028430681 0.634512870548731 4.48238928018911e-05 307.790258053774 74.3433308577837 4.1401192884748 4.6303562653002e-05 573.313887455257 277.435920104436 2.06647317780424 0.0397268192834704 TMEM214 other 0.344785383432146 1 0.448403700731671 4.1401192884748 2.06647317780424 9.2258583043488e-05 83.3640214577823 19.0302368899684 4.38060870917098 1.69514706226192e-05 27.5378441457628 63.9591694646001 0.430553498056355 0.667136546584427 ATAD2B other 0.686964347020807 1 0.170752163581643 4.38060870917098 0.430553498056355 0.011155527638457 30.1209080890456 12.5206517566028 2.40569809580089 0.016809314102063 91.307921534053 43.7682422576646 2.08616834545288 0.0378950037130654 FKBP1B other 1 1 1 2.40569809580089 2.08616834545288 2.20862947585122e-06 443.6724186242 85.7279417267554 5.17535367918126 4.42466644884488e-07 341.292563707406 316.636367862942 1.07786912163904 0.282047145617199 ATL2 essential 0.0191046449661131 1 0.00502465121930824 5.17535367918126 1.07786912163904 0.020975391536755 261.460629385988 93.9485066506741 2.78302060040367 0.00576148812426164 -109.730075893059 360.00662232335 -0.304800159466239 0.760750594217853 YPEL5 other 1 1 1 2.78302060040367 -0.304800159466239 3.41393250626273e-07 168.911662360487 30.7907069126745 5.48580007726154 9.41507552396218e-08 162.823918242059 115.88640424044 1.40503037702537 0.161153279980531 FAM98A other 0.00316061871429804 1 0.0011149332435476 5.48580007726154 1.40503037702537 2.61539451308096e-09 259.633705380488 40.3237883495821 6.43872304679376 5.48590271562069e-10 204.537462459097 158.531177248169 1.29020339096397 0.198083916231696 YIPF4 other 2.76002582965434e-05 1 7.15306855089782e-06 6.43872304679376 1.29020339096397 1.97970796087276e-19 370.252299232339 36.750021391368 10.0748866317478 2.06463955904177e-20 -35.503561035149 229.650045371239 -0.154598536994652 0.877255947751376 AFTPH other 2.8705765432655e-15 1 3.16571183587874e-16 10.0748866317478 -0.154598536994652 3.86529168783191e-08 187.526155576422 31.1064017227726 6.02853898845961 5.55045858250089e-09 -11.352240579993 194.383194798593 -0.0584013478724611 0.95347312159586 LGALSL other 0.000379764908329485 1 6.96693561275511e-05 6.02853898845961 -0.0584013478724611 0.404137407469174 -17.7583379511793 13.1765958061724 -1.34771819765926 0.178878773309181 -1.08254412521303 68.1079789550874 -0.0158945272172427 0.987330274710567 CNRIP1 other 1 1 1 -1.34771819765926 -0.0158945272172427 0.0699821999606773 99.4556635871925 54.1061827613742 1.83815709243109 0.0671888609179324 -451.26525941579 325.534347182008 -1.38622932824808 0.166873714668787 BCL11A og 1 1 1 1.83815709243109 -1.38622932824808 1.08060338235179e-08 189.923163356961 30.4334323644241 6.24060937598929 1.7031588794024e-09 15.0971570415965 125.496558621729 0.120299370814639 0.904336476412546 CRIPT other 0.000109886557951354 1 2.18208715629036e-05 6.24060937598929 0.120299370814639 5.18108629606525e-18 2901.10291113568 303.487299048739 9.5592234674367 8.22227742303463e-19 -202.898673445561 1440.20412109399 -0.140881886444983 0.888069480743267 EPCAM other 7.34315360741328e-14 1 1.24978616830126e-14 9.5592234674367 -0.140881886444983 0.120306773656894 18.0525247345253 21.7241219365374 0.8309898456316 0.406721850962654 -76.6672395255312 50.0790980563951 -1.53092292994563 0.126972363128681 SLC17A5 other 1 1 1 0.8309898456316 -1.53092292994563 0.0233560429616592 96.5614701961666 93.5267573116996 1.0324475366376 0.302821912917052 -458.29165482498 213.026301085947 -2.15133836755715 0.0323709208699171 OGFRL1 other 1 1 1 1.0324475366376 -2.15133836755715 2.4000345871333e-13 78.3442885908327 33.3340804934524 2.35027597675063 0.0194741357865348 -233.762368747369 47.5797089358694 -4.91306849023493 1.55040213872842e-06 SLF2 other 3.02332356941181e-09 0.0241924749727183 1 2.35027597675063 -4.91306849023493 4.67275271472e-10 146.102632661072 61.0128399363073 2.39462107998237 0.0173146164474689 -306.165590331585 86.3034509976637 -3.54754748265944 0.000457809878954918 IDE other 5.14236436254936e-06 1 1 2.39462107998237 -3.54754748265944 0.000594546133087103 56.4633160198068 16.9929795882449 3.32274370875287 0.00101356104005786 8.12428789920791 23.9061295363743 0.339841206283368 0.73423838869801 ELOVL3 other 1 1 1 3.32274370875287 0.339841206283368 0.190508147549772 98.2694748816148 164.323535687691 0.598024345510572 0.550324972873152 -234.364548215001 235.414140980094 -0.995541505022918 0.320364327526248 IFIT3 other 1 1 1 0.598024345510572 -0.995541505022918 0.0295853690662656 10.5711351066632 5.53174835490692 1.9109934921906 0.0570526629882614 -6.37600393903653 8.9110792396157 -0.715514223091063 0.474902857746936 NKX2-3 other 1 1 1 1.9109934921906 -0.715514223091063 0.4359777569382 -2.68755305259802 88.2526720523584 -0.0304529368924213 0.975728324905685 -131.141423530085 126.433057160418 -1.03723999462967 0.300552052241114 IFIT2 other 1 1 1 -0.0304529368924213 -1.03723999462967 5.07083517230168e-06 109.83805023829 24.0205249894363 4.57267483898016 7.31953051812451e-06 24.8668753351168 34.2280754544355 0.726505215527517 0.46815384491377 GPAM other 0.0425848737769895 1 0.0760206439612412 4.57267483898016 0.726505215527517 7.42110647839506e-13 112.821915298358 17.9285362694327 6.29286817411383 1.23593647798358e-09 -32.2325851667374 28.9191705338828 -1.1145750231312 0.266012828787654 CUTC other 9.19178248414013e-09 1 1.59250415188184e-05 6.29286817411383 -1.1145750231312 0.057012310550277 61.5557836530696 34.1373104661046 1.80318199684153 0.0724662403073682 -7.18877159407733 48.8603408777343 -0.147128969322301 0.883139219351858 PPP1R3C other 1 1 1 1.80318199684153 -0.147128969322301 0.00107646055601383 50.7148404993069 23.8855693751694 2.12324184961771 0.0346332160637785 -62.7459546925564 37.5536086586662 -1.67083688981449 0.0958998456301813 CNNM1 other 1 1 1 2.12324184961771 -1.67083688981449 5.67015481455649e-10 269.474707759024 71.4732552952913 3.7702873144044 0.000200183308552845 -260.467366940622 101.390468054788 -2.56895319587513 0.0107363093184813 MXI1 other 6.2082525064579e-06 1 1 3.7702873144044 -2.56895319587513 5.94250551816929e-16 251.102487471363 38.7365025871444 6.48232211739987 4.25225474665157e-10 -81.2947303652266 54.9507939982525 -1.47940956718136 0.140192359904803 SMNDC1 essential 8.04971797491212e-12 1 5.5674771397909e-06 6.48232211739987 -1.47940956718136 2.23227690628295e-10 41.0216984661428 10.7372013515497 3.82052055494164 0.000164927391312524 -40.1354715243603 14.9173297942646 -2.69052652705925 0.00757380838251524 C10orf88 other 2.49791785813062e-06 1 1 3.82052055494164 -2.69052652705925 1.02276407689459e-18 445.879400231523 47.1441286783085 9.45779278845123 1.57708999189369e-18 151.724430150656 80.2138200484335 1.89149986946195 0.059623883941437 HELLS other 1.4660300278207e-14 1 2.39244551770273e-14 9.45779278845123 1.89149986946195 4.98875761913836e-23 331.120322775476 36.5797136330038 9.05202063902229 2.77943146437423e-17 -64.5526909819423 57.4902220971453 -1.1228464359185 0.262492845140974 TCTN3 other 7.53352288066083e-19 1 4.17164868487929e-13 9.05202063902229 -1.1228464359185 2.18841428947471e-10 89.2542301597877 22.4957988644415 3.96759549183511 9.30943224443117e-05 -80.0565166525989 31.2343593472455 -2.56309136238644 0.0109168388269462 FAM45A other 2.45014863849588e-06 1 0.875924479878529 3.96759549183511 -2.56309136238644 1.07032231301546e-07 181.575023109836 69.4756573845269 2.61350564996993 0.00945899232594807 -362.99822680237 110.663900393859 -3.28018645204479 0.00117213831107194 AVPI1 other 0.00102354922793669 1 1 2.61350564996993 -3.28018645204479 6.19542047319466e-09 296.01888725991 81.4903831470343 3.63256222179983 0.000335778261731472 -265.831021665409 113.145566685452 -2.34946034080528 0.0195213092637876 WDR11 other 6.39739118062081e-05 1 1 3.63256222179983 -2.34946034080528 1.08117224246008e-18 93.5783478038505 25.6064602352551 3.65448199181437 0.000309192281622657 -184.784891805994 35.8548503127669 -5.15369302044462 4.91663834762163e-07 C10orf76 other 1.54921170622105e-14 0.00772502217178311 1 3.65448199181437 -5.15369302044462 0.000363236964393824 3.65160555765273 4.29528331410251 0.850143119934273 0.395993222900174 -16.0227079553342 6.01437054802421 -2.66407063339286 0.00818099692406916 KCNIP2 other 1 1 1 0.850143119934273 -2.66407063339286 0.0255319833240785 -3.48632136766119 5.55403765761895 -0.627709349949888 0.53072097909873 -21.4195339059681 8.4230957708372 -2.54295267306917 0.0115464062492906 CFAP58 other 1 1 1 -0.627709349949888 -2.54295267306917 1.96973587637089e-18 809.30624176982 85.2685269692466 9.4912656584499 1.19313402182791e-18 359.954839633121 137.358851436952 2.62054345873982 0.00927073526301242 GOT1 other 2.81357072580817e-14 1 1.81201263895004e-14 9.4912656584499 2.62054345873982 1.05576898564382e-07 12.0307398047954 6.54046048417635 1.83943314601502 0.0669372818759739 -30.6670998413692 9.20919835546525 -3.33005096183749 0.000987897593381683 C10orf95 other 0.00101015976546401 1 1 1.83943314601502 -3.33005096183749 0.165967193229538 -2.49825081770236 25.9489711548615 -0.096275524867363 0.923372385158652 -70.4582058421035 41.3326691291482 -1.70466140529056 0.0893952638877272 SFRP5 other 1 1 1 -0.096275524867363 -1.70466140529056 6.68244121615549e-10 605.977856858648 111.147266079872 5.45202665104858 1.12089571436906e-07 -626.091019297842 241.630867595712 -2.59110529017921 0.0100850581944025 GNA13 other 7.29254809919048e-06 1 0.00132232067424118 5.45202665104858 -2.59110529017921 0.313006491352318 25.7525031853405 46.0146519877718 0.559658762434715 0.576176193688339 -117.419120621802 101.413579356354 -1.15782443896597 0.247958859663015 HOXB8 other 1 1 1 0.559658762434715 -1.15782443896597 5.80421851063518e-10 227.362335859001 48.8265703492708 4.65652889876581 5.09102464198509e-06 -316.68249560098 105.709396353732 -2.99578378577884 0.00299665654728749 KANSL1 essential 6.35445842544339e-06 1 0.0535168510365473 4.65652889876581 -2.99578378577884 0.241720708799686 -3.93532322880054 17.5015618582951 -0.224855544931571 0.822261105998233 -63.5814335052622 38.459396488376 -1.65320934051784 0.0994461969971458 HOXB5 other 1 1 1 -0.224855544931571 -1.65320934051784 0.339056310108892 -11.811395713539 48.7279003347434 -0.242394924312332 0.808656834895092 -155.219087614606 107.089359410756 -1.44943520503509 0.148368048186122 HOXB3 other 1 1 1 -0.242394924312332 -1.44943520503509 0.0334058892853747 712.859281916338 829.894069969304 0.858976232885609 0.391109983930977 -2364.87241306456 1344.92045969565 -1.75837343838142 0.0798085990404496 DUSP1 other 1 1 1 0.858976232885609 -1.75837343838142 5.16436914288883e-06 377.481590480413 96.1435574565046 3.9262286570911 0.000109507792779982 -146.496841908956 155.462727543913 -0.942327747772052 0.346864139076727 PANK3 other 0.0433290571088373 1 1 3.9262286570911 -0.942327747772052 0.0408158625781404 119.602727464235 48.1136606635306 2.48583719914067 0.0135255452633797 130.277649562976 78.5188553126509 1.65918936342397 0.0982301851411546 MSX2 other 1 1 1 2.48583719914067 1.65918936342397 0.353828550018025 -70.0015537764667 76.1249801694347 -0.919560880287406 0.358714185443308 -294.753542083642 211.251066184925 -1.39527599745045 0.164206449870585 TEK other 1 1 1 -0.919560880287406 -1.39527599745045 2.47857826554977e-40 255.896110027065 17.3862089501496 14.7183385843792 2.61520357788101e-36 -61.5913022294015 61.0681677023936 -1.00856640286896 0.314095752826116 RCL1 other 3.93300799177438e-36 1 4.14849743559265e-32 14.7183385843792 -1.00856640286896 2.75167641085855e-25 188.416411758475 19.0920416189936 9.86884564357069 1.68157876703375e-19 -123.367535703266 54.6964204383913 -2.25549560125646 0.0250036283557685 CAAP1 other 4.22052127897484e-21 1 2.56726630363042e-15 9.86884564357069 -2.25549560125646 0.0334773359378605 93.906154929224 36.8967608061466 2.54510566449455 0.0115463971897745 44.8982349835314 99.4644941880067 0.451399621041305 0.652105809111669 MOB3B other 1 1 1 2.54510566449455 0.451399621041305 2.76947151876649e-20 529.055850175232 52.3165649424897 10.1125876814888 1.56479027626609e-20 275.795327395131 183.469775979369 1.50321940452003 0.133977743866526 CD274 other 4.06198387657481e-16 1 2.40101419990269e-16 10.1125876814888 1.50321940452003 2.6329920523814e-22 294.487438447835 32.4514537531486 9.07470712060973 2.40843349391767e-17 -158.214601167526 60.7450960467083 -2.604565824472 0.00970682803693065 NUP43 essential 3.95212107062448e-18 1 3.61722626451495e-13 9.07470712060973 -2.604565824472 8.62450885221642e-10 252.175213591664 57.6774660355459 4.37216179775046 1.75535113785922e-05 -346.249652974641 105.376358011575 -3.2858381093092 0.00115077438471893 MTHFD1L other 9.35155494845826e-06 1 0.176640985002774 4.37216179775046 -3.2858381093092 0.0272309789426202 196.455466370342 100.891355631616 1.94719820286347 0.0525400078325319 -204.414705969895 188.750443030336 -1.08298927773664 0.279772285286596 LRP11 other 1 1 1 1.94719820286347 -1.08298927773664 0.443684778646317 -15.5210315921539 22.1343290601096 -0.701219881117873 0.483765281520892 -52.0817226564399 42.0042142343562 -1.23991660374499 0.216074859087468 CCDC170 other 1 1 1 -0.701219881117873 -1.23991660374499 1.79008034219176e-17 442.933122829655 55.2507967647993 8.01677349043862 3.26494980882498e-14 -196.355183237211 103.422638063149 -1.89857063128982 0.0586831630950515 PCMT1 other 2.51166172812926e-13 1 4.72013793861827e-10 8.01677349043862 -1.89857063128982 2.13955090661445e-06 281.464115688276 66.2921111129428 4.24581614558543 2.99544631000104e-05 -179.114964558652 121.973978939158 -1.46846865303949 0.143136720440064 PLEKHG1 other 0.0185434877076274 1 0.295740414186403 4.24581614558543 -1.46846865303949 0.507217044398141 -7.58273768953244 22.2104894487492 -0.341403448448519 0.733063470099318 -49.2496553414052 42.2320053392503 -1.16616899779639 0.244567621674319 MYCT1 other 1 1 1 -0.341403448448519 -1.16616899779639 0.00188613772672286 84.5326788245849 71.6866510290931 1.1791969301269 0.239357810966807 -283.302674934822 117.786359920827 -2.40522480807838 0.016835618587888 CYSTM1 other 1 1 1 1.1791969301269 -2.40522480807838 1.80080906268894e-19 191.551628239747 30.3490112232368 6.31162665665644 1.12249213953933e-09 -194.267188257287 50.2557257224716 -3.8655732349801 0.000138786376940378 WDR55 essential 2.61207354543031e-15 1 1.44823935843364e-05 6.31162665665644 -3.8655732349801 0.000663461851603759 18.8648892905551 45.0738479851417 0.418532921723785 0.675887793812009 -243.358299442689 74.7201784251089 -3.25692877843705 0.00126911126232408 ARAP3 other 1 1 1 0.418532921723785 -3.25692877843705 0.203822717907929 21.7969548182315 13.2856275614525 1.64064171733025 0.102023415588146 3.05567816738027 23.1773907498235 0.131838747526123 0.895208948794448 PCDHB8 other 1 1 1 1.64064171733025 0.131838747526123 0.05842351399554 31.4787977979469 16.1475117605607 1.94945191957265 0.0522653162832864 -9.19775289722089 28.1700798837513 -0.326507874140826 0.744290304401424 PCDHB10 other 1 1 1 1.94945191957265 -0.326507874140826 0.10390229383731 48.9968258691663 31.7066662167857 1.54531622890164 0.123428182181101 -32.5368338320478 55.3137432824684 -0.588223322111709 0.556868704455433 PCDHB14 other 1 1 1 1.54531622890164 -0.588223322111709 0.064773024757431 17.598968407479 7.48496942966788 2.35124118713467 0.0194220911296131 13.9821262268068 13.0578747913455 1.07078115315318 0.285213588150364 PCDHB12 other 1 1 1 2.35124118713467 1.07078115315318 0.3973943159918 5.64175452971369 4.92934657094007 1.14452381233924 0.253431434399514 -10.0042643209037 15.8678703898941 -0.63047302978194 0.528924384963241 TNN other 1 1 1 1.14452381233924 -0.63047302978194 1.17365898570868e-15 127.712525250939 14.5436435298154 8.78132945084359 1.98388065850207e-16 -17.1018149276228 46.4491966058702 -0.368183223333974 0.713028347230915 MRPS14 essential 1.57810187218389e-11 1 2.95499024083884e-12 8.78132945084359 -0.368183223333974 1.67734160274683e-14 116.886707566638 14.1824134818163 8.24166547650734 7.52892661474449e-15 -51.6178747714847 45.4320577787284 -1.13615533381481 0.256902736063857 CENPL other 2.18591157669967e-10 1 1.09877155015581e-10 8.24166547650734 -1.13615533381481 0.531271374082106 14.2251977215916 14.0530024788366 1.01225327064549 0.312323225120738 -17.9943364203854 45.0585710787872 -0.399354351227015 0.689947826968475 TNFSF18 other 1 1 1 1.01225327064549 -0.399354351227015 0.336196282020568 5.19367233985362 12.3860802549961 0.419315250097679 0.67532291293191 -53.2666902879763 38.9978475630923 -1.36588795578523 0.173123553251796 SEC16B other 1 1 1 0.419315250097679 -1.36588795578523 5.56890457217302e-09 93.5156390579516 14.8626928183972 6.29197146173921 1.25378142615627e-09 -37.5288700714476 49.9985015657773 -0.750599895920384 0.453544703565517 GORAB other 5.76270245128464e-05 1 1.61499585503189e-05 6.29197146173921 -0.750599895920384 4.05991123030495e-12 564.091807016383 85.2808628340707 6.61451805563841 1.96972987530134e-10 -262.355379224782 168.902390950681 -1.55329582812944 0.121515213869576 ACAT2 other 4.88488519230291e-08 1 2.60890721983662e-06 6.61451805563841 -1.55329582812944 4.35128064984488e-23 1934.43682977962 206.340753779411 9.37496250424495 2.8047266748147e-18 -1204.42131239178 408.666675098236 -2.94719727783593 0.00348475876451895 TCP1 essential 6.5752201899806e-19 1 4.24635618566945e-14 9.37496250424495 -2.94719727783593 1.14453853500496e-15 280.378806591715 61.9220423774583 4.52793215189204 8.95660691734518e-06 -473.889274909593 112.704337933246 -4.20471193566901 3.56259565183787e-05 SNX19 other 1.53974769114217e-11 0.540089500818621 0.0922978342832421 4.52793215189204 -4.20471193566901 0.0858748837184033 -9.11312454427335 29.5964568016896 -0.307912687161698 0.758386169900424 -110.754146661356 53.9342163373442 -2.05350432772803 0.0409868700606628 KCNJ5 other 1 1 1 -0.307912687161698 -2.05350432772803 0.0377284227751758 25.0797777892355 14.1679202729421 1.77018061268547 0.0778172332648175 -18.814976770308 25.372609687854 -0.741546770386603 0.459001758701699 MSANTD2 other 1 1 1 1.77018061268547 -0.741546770386603 0.0362275200265817 65.4180366566442 40.4149579550379 1.61865903038728 0.106688149514227 -67.490956305813 73.6489877898913 -0.916386746527377 0.360281846239983 TP53AIP1 other 1 1 1 1.61865903038728 -0.916386746527377 6.75219899384308e-19 29.202367861897 10.6875632434847 2.73236912817327 0.00670451777825169 -84.6608448460692 15.3628200665896 -5.51076198765004 8.36214722308991e-08 SLC10A7 other 9.71708957203958e-15 0.00132238996185944 1 2.73236912817327 -5.51076198765004 6.50073834275983e-16 178.833558149676 20.7024783580591 8.63826808832574 5.30034704617927e-16 -54.2949712133661 82.7124537964018 -0.656430425181366 0.512112550975067 NUDCD1 other 8.79744919925688e-12 1 7.85246414891459e-12 8.63826808832574 -0.656430425181366 5.89314675470008e-11 248.604952061809 35.1973147887659 7.06317949405496 1.4116192215708e-11 8.5586521455832 139.246422640667 0.0614640719903396 0.951035610239666 ENY2 other 6.77240425050133e-07 1 1.93405949547416e-07 7.06317949405496 0.0614640719903396 4.81642711188761e-12 165.785781005673 32.450517838842 5.10887936608621 6.12197910437808e-07 -108.454002500731 53.7166672008785 -2.01900095728496 0.0444717036457266 MASTL essential 5.77393282173087e-08 1 0.00688722649242534 5.10887936608621 -2.01900095728496 7.30053924446626e-09 247.162651306855 191.039545636855 1.29377742436994 0.196843882861464 -1405.48168988064 315.166009458472 -4.45949641681089 1.20452881278427e-05 KIAA1217 other 7.49984396584019e-05 0.185063806796175 1 1.29377742436994 -4.45949641681089 0.00958899895551886 135.015897977455 164.691555633592 0.819810690706209 0.413049826417089 -555.14555354041 277.922052753031 -1.99748651840064 0.0467793988510049 PLXDC2 other 1 1 1 0.819810690706209 -1.99748651840064 6.84300103029121e-15 55.9551875304429 24.7061355702609 2.26482961575735 0.0243072528012327 -251.757819945361 42.7703679932505 -5.88626733314735 1.15551337839936e-08 EPC1 other 9.0163381575117e-11 0.000183553300158738 1 2.26482961575735 -5.88626733314735 0.438486206390294 -8.35095282220701 6.50276871214843 -1.28421495394813 0.200205512407808 -9.42126626646793 28.9030005444134 -0.325961529564755 0.744714654133243 IQSEC3 other 1 1 1 -1.28421495394813 -0.325961529564755 9.90496747061877e-20 95.2312218763646 9.67496634284572 9.84305459075675 1.17649887117406e-19 -26.7247077431902 43.4711331363492 -0.614769062020237 0.539240780727484 CCDC77 other 1.44216326372209e-15 1 1.79839617447667e-15 9.84305459075675 -0.614769062020237 9.72023257861154e-18 78.6861525542342 23.6602362998366 3.32567061279847 0.0010038587862759 -192.332316305108 34.3879147629111 -5.59302061875955 5.44849131241243e-08 TAF12 other 1.3707471982358e-13 0.000862659629494259 1 3.32567061279847 -5.59302061875955 0.319990294981109 -1.36287141577235 6.73956685055378 -0.202219437241781 0.839895790733676 -14.9244621476859 10.6585232885879 -1.40023732590287 0.162577721796802 ENOX1 other 1 1 1 -0.202219437241781 -1.40023732590287 0.0016730648356191 -1.40212246449717 6.57435726843039 -0.213271413044446 0.831275033139241 -33.8104477954359 10.443638663609 -3.23742029808527 0.00135564795561171 TNFSF11 other 1 1 1 -0.213271413044446 -3.23742029808527 3.20956038194184e-19 47.1607966779958 8.68187564275982 5.43209769623056 1.23644087945127e-07 -63.0359671863582 13.7915188410531 -4.57063271368776 7.38607040544068e-06 MTRF1 other 4.63941953209693e-15 0.113952294215139 0.00145454905058647 5.43209769623056 -4.57063271368776 0.0483604218074873 50.8056641280747 22.8016769044148 2.22815472480613 0.0266909693121943 8.43693693063523 34.8648895668344 0.241989492450908 0.808971324166884 SOHLH2 other 1 1 1 2.22815472480613 0.241989492450908 0.000549212724096384 87.701162777168 55.9029720062145 1.5688103803751 0.117850438437783 -206.812256865931 88.4097067722619 -2.33924830673477 0.0200439196322632 DNAJC15 other 1 1 1 1.5688103803751 -2.33924830673477 6.07022393668924e-19 445.012261674701 61.5716628741512 7.22754983220575 4.97479269804068e-12 -216.325712725914 96.0625370718656 -2.25192587370535 0.0251248167604228 PROSER1 other 8.74355055840717e-15 1 6.89506267948438e-08 7.22754983220575 -2.25192587370535 7.08787395676661e-13 245.614977189038 64.9587047926264 3.78109412700171 0.000191965882608293 -416.232764008802 101.225711384815 -4.11192727929044 5.20135913376477e-05 UFM1 other 8.78541976941221e-09 0.784625025328415 1 3.78109412700171 -4.11192727929044 2.48935462679658e-19 80.4484197012771 14.3291820586944 5.61430648112007 4.85047700884351e-08 -99.8305401600268 22.6613852292986 -4.40531499508499 1.518678224783e-05 WBP4 other 3.60483443506413e-15 0.232722251165747 0.000583415374623697 5.61430648112007 -4.40531499508499 2.12850413921602e-08 220.769547904666 72.4970497675496 3.04522113123953 0.00255231211475553 -354.263672118663 115.360848571395 -3.07091770306643 0.00234931485440646 ELF1 other 0.00021253113830072 1 1 3.04522113123953 -3.07091770306643 0.0933633573305207 20.6684256612379 29.310133016426 0.70516314783201 0.48131212427498 -63.1511555646371 44.7470094514923 -1.41129332079936 0.159300946475218 SMAD9 other 1 1 1 0.70516314783201 -1.41129332079936 2.05832325105396e-09 883.008765515707 235.906399574943 3.74304710303203 0.000222305315494186 -946.283318861475 360.371547029097 -2.6258546954182 0.0091382336867569 HSPH1 other 2.18676262191972e-05 1 1 3.74304710303203 -2.6258546954182 1.18653087276061e-06 76.3207721336844 19.9958487365739 3.81683084019775 0.000167284660662393 -42.8255640322535 31.6231330825574 -1.35424797791067 0.17677714064614 KBTBD7 other 0.0105067308782952 1 1 3.81683084019775 -1.35424797791067 1.90265358930325e-06 83.3683847233595 41.7412404723085 1.99726658288143 0.0467922976740144 -200.177338251496 63.7252543645793 -3.14125600984281 0.0018679518604468 ALG5 other 0.0165797233771885 1 1 1.99726658288143 -3.14125600984281 6.7439900502069e-18 174.009851773985 27.5134890832546 6.32452871562161 1.03879883343005e-09 -122.175933162419 42.0041203962454 -2.90866543591138 0.00392938342733251 EXOSC8 essential 9.5373507290026e-14 1 1.34150481349156e-05 6.32452871562161 -2.90866543591138 9.99702654969395e-16 706.92449739967 114.782790417683 6.15880215864454 2.6244742820012e-09 -512.385376077002 190.278641907129 -2.69281602465445 0.00752499144088356 ETF1 essential 1.34639953571278e-11 1 3.33728149699272e-05 6.15880215864454 -2.69281602465445 0.40090754081253 1580.78177481394 1260.26344278225 1.25432645362155 0.210796257859147 302.039188203912 2094.76483150163 0.144187635605566 0.885458685427836 TGFBI other 1 1 1 1.25432645362155 0.144187635605566 5.59880233064886e-09 256.941118095899 50.5234213222532 5.085584296777 6.83423819772168e-07 -84.7336065605805 83.2517111551505 -1.01780017953827 0.30967737354925 FAM53C other 5.79140113082319e-05 1 0.00766186444346577 5.085584296777 -1.01780017953827 2.68690120248803e-09 182.224124993215 46.1242671135959 3.95072130998699 9.94337483119679e-05 -201.198151796632 75.8609216700616 -2.65219756585206 0.00846840990096343 SIL1 other 2.83441207850463e-05 1 0.933285161656131 3.95072130998699 -2.65219756585206 2.01400118349472e-10 433.083795011641 90.7858251342954 4.77039002918132 3.0079558771107e-06 -323.274817271184 149.31611492716 -2.16503635544553 0.0312577296518897 PAIP2 other 2.25829952705262e-06 1 0.0322121994879785 4.77039002918132 -2.16503635544553 1.96089011562783e-10 442.131715959777 90.3035942489201 4.8960588959621 1.67884551769601e-06 -303.444587600826 149.833862934089 -2.02520699699446 0.0438226743563585 KDM3B other 2.19992262072286e-06 1 0.0183145257525458 4.8960588959621 -2.02520699699446 0.289738229615175 682.784429092597 923.392760786877 0.73943012993816 0.460283509623131 -1340.39674765195 1530.73400489777 -0.875656216797425 0.381989565354606 EGR1 other 1 1 1 0.73943012993816 -0.875656216797425 1.68319072635286e-12 974.3028852781 125.889508339872 7.73934935584711 2.00610120902705e-13 581.245153870012 822.268123728537 0.706880319322586 0.480250460772792 SERP1 other 2.05803730111164e-08 1 2.86671862769966e-09 7.73934935584711 0.706880319322586 0.0600923792690299 67.6372844689784 29.7128765419812 2.27636272016322 0.0236103086692107 159.654105461283 163.419000258348 0.976961707077429 0.329465870961324 PLS1 other 1 1 1 2.27636272016322 0.976961707077429 7.18884851997186e-12 48.661842994491 6.74219261750723 7.21751005275826 5.45702302943556e-12 -15.6666065996662 33.1067982065593 -0.473214187065733 0.636445579043408 ZFP30 other 8.57126409036245e-08 1 7.55361127734471e-08 7.21751005275826 -0.473214187065733 2.01838534786185e-12 90.1412209577135 15.9049630641763 5.66749011575789 3.6900617158269e-08 -123.45466858161 36.6544591465565 -3.36806684523696 0.000866373489418791 NR2C1 other 2.45980622343924e-08 1 0.00044553805156894 5.66749011575789 -3.36806684523696 3.32287025816076e-06 130.478215783914 39.8067129992995 3.27779427018276 0.00118329374906378 -250.670252959162 87.582452248635 -2.862105895911 0.00453795051021679 UTP20 essential 0.0283108545995297 1 1 3.27779427018276 -2.862105895911 4.03801874823098e-07 877.471389413184 193.792401923345 4.52789366716384 8.93244387316944e-06 -751.389577131581 418.068240723782 -1.79728930337003 0.0734029492570622 TMPO other 0.00371699625774662 1 0.0920577665568843 4.52789366716384 -1.79728930337003 0.00057220610986526 172.325397429736 69.7694538061223 2.46992613570689 0.0141303600876736 -339.733079510913 153.512400484626 -2.21306603530662 0.0277264437438916 ARL1 other 1 1 1 2.46992613570689 -2.21306603530662 0.233902383392324 -32.1432238886636 19.1415883342067 -1.67923493742797 0.0942503455901293 -34.1486943597516 41.2825231575122 -0.827194942263057 0.408849022365883 GLT8D2 other 1 1 1 -1.67923493742797 -0.827194942263057 8.39129740793817e-05 48.3730984756952 14.844617807518 3.25862875709718 0.00126181856676558 -61.2014895399981 33.0052352810092 -1.85429641749024 0.064779081628838 MTERF2 other 0.627669046113775 1 1 3.25862875709718 -1.85429641749024 0.528022965975754 63.9260948937583 84.2498001591655 0.758768504767828 0.448650465742316 -116.269234555951 193.07261590395 -0.602204688694915 0.547541414338271 SOCS2 other 1 1 1 0.758768504767828 -0.602204688694915 5.01420385253157e-07 97.8071882178079 31.5228697952816 3.10273743643886 0.00211856678213481 -229.908199244521 67.9851420683519 -3.38174183725868 0.000825635665902548 NFYB essential 0.00457997379890234 1 1 3.10273743643886 -3.38174183725868 0.00716982376330945 46.0139735483749 17.5066465941782 2.62837164735346 0.00906891851054215 -36.7311096824932 38.5195410956831 -0.953570801667977 0.341150704699645 WASHC3 other 1 1 1 2.62837164735346 -0.953570801667977 0.000119637086446739 47.1592857040651 20.1749971455926 2.33751139411523 0.0201434896200193 -121.61395640718 43.5203606254089 -2.79441518083784 0.00557199810061394 APAF1 other 0.877059480741041 1 1 2.33751139411523 -2.79441518083784 0.262492673181052 148.880891471186 110.001315490371 1.35344646386722 0.177045027316933 21.8659998940077 189.363386262689 0.115471107300937 0.908157551036687 DUSP4 other 1 1 1 1.35344646386722 0.115471107300937 5.22399205173515e-12 89.0175359712235 155.769319733456 0.571470274913863 0.568151084135678 -1451.32329136691 259.724075292546 -5.58794285717323 5.55936952287696e-08 TNFRSF10B other 6.25677528036319e-08 0.000880103789166651 1 0.571470274913863 -5.58794285717323 6.24388421877158e-10 144.897637852316 120.527084974164 1.20219980333363 0.230335536727397 -923.89157701999 201.255198577494 -4.59064701707193 6.76836809922178e-06 SORBS3 other 6.82518983953921e-06 0.104483298347687 1 1.20219980333363 -4.59064701707193 1.65065742755147e-06 8.86021999440239 138.994439962938 0.0637451397103718 0.949219982008494 -970.931862429766 235.962438227926 -4.11477296861927 5.14133656240911e-05 PTK2B other 0.0144498551207856 0.775879100633159 1 0.0637451397103718 -4.11477296861927 3.1460746375407e-12 10.7892285117923 16.9347949128652 0.637104173230694 0.524592851651975 -160.905319545221 28.2928113418972 -5.68714496416783 3.32999131948618e-08 PPP3CC other 3.80203119946794e-08 0.000527836924051755 1 0.637104173230694 -5.68714496416783 0.0406157647275981 -52.4328988686267 70.1398200328053 -0.747548237849814 0.455383252246799 -280.2253030028 116.963562228276 -2.39583420395395 0.0172636733317043 PDLIM2 other 1 1 1 -0.747548237849814 -2.39583420395395 0.00228068370307426 81.1103370013313 50.9691593623332 1.5913610900413 0.112689834009108 -128.73795790315 86.5272533258936 -1.48783132429127 0.137953752663815 EPHX2 other 1 1 1 1.5913610900413 -1.48783132429127 7.59329385711569e-19 111.127834689759 20.4342716088837 5.43830662608233 1.19493280380121e-07 -126.134479473562 31.9981950050738 -3.94192483212137 0.000102770280253544 UBIAD1 other 1.09182986231782e-14 1 0.00140691388319555 5.43830662608233 -3.94192483212137 5.32103477090576e-06 512.647842535253 124.975238611678 4.10199530907197 5.41079527977747e-05 -41.936570931437 195.699760306776 -0.214290354089847 0.830480610438218 TARDBP other 0.0445849503454194 1 0.521167801348166 4.10199530907197 -0.214290354089847 0.553012950402106 11.6972415726703 11.219700462239 1.04256273258261 0.298073205373727 5.4461955701253 17.7618758074046 0.306622770544025 0.759364250297317 TNFRSF8 other 1 1 1 1.04256273258261 0.306622770544025 1.55399410943807e-06 248.698556013863 50.8202752223578 4.89368770487198 1.69437531692923e-06 -172.902650370343 203.002385268207 -0.851727186071746 0.395112041772734 ZNF706 other 0.0136331903221002 1 0.0184822459570641 4.89368770487198 -0.851727186071746 0.000819127903915947 522.388235461437 137.214163781208 3.80710140313502 0.000176780562449729 428.798189049915 441.357397643013 0.971544130312149 0.332212692959055 LYPLA1 other 1 1 1 3.80710140313502 0.971544130312149 0.00479561191415783 194.179141173111 64.7099431195922 3.00076204385226 0.00294676129649935 -72.6138578147843 214.589304064832 -0.338385261703659 0.735337821682688 CRISPLD1 other 1 1 1 3.00076204385226 -0.338385261703659 1.22856770724594e-14 279.795783788706 37.7102577512093 7.41962003109706 1.55593927907463e-12 -143.187274530074 121.03856809926 -1.18298883387856 0.237861942257888 COPS5 essential 1.60758084493131e-10 1 2.18251602675799e-08 7.41962003109706 -1.18298883387856 0.549142517877463 190.566566726919 218.28820206101 0.873004426843264 0.383442182864445 -251.377864989331 723.881232274692 -0.347263962348371 0.728665569680236 RDH10 other 1 1 1 0.873004426843264 -0.347263962348371 7.4196339713711e-10 391.089280547787 68.3906148035875 5.71846417335135 2.83526292591703e-08 -274.2168204782 146.828128419481 -1.8676041398197 0.0628966177774382 AKAP1 other 8.07701354123458e-06 1 0.000344257624464846 5.71846417335135 -1.8676041398197 5.89509571469045e-17 170.069023260922 19.6231921855924 8.66673585278282 4.11788501601451e-16 -34.873782437251 41.8372133947717 -0.833558920575935 0.405263662277102 COIL other 8.18121383284741e-13 1 6.11052957526394e-12 8.66673585278282 -0.833558920575935 0.00148310846349075 1188.34480784068 371.141531181782 3.20186427009872 0.00152821403585137 -647.211776319206 796.805476287412 -0.812258192971747 0.417356418438406 SCPEP1 other 1 1 1 3.20186427009872 -0.812258192971747 6.45831973913171e-12 172.708299562327 35.0247233935406 4.93103964367577 1.43057940877392e-06 -301.322995546087 78.2031310768702 -3.85308096231978 0.000145789900703462 SPOP other 7.71058793654935e-08 1 0.0156905949554324 4.93103964367577 -3.85308096231978 0.965492302200706 13.9727723702505 54.6024013021373 0.255900327403799 0.798227836292296 0.528793515977989 117.184731494539 0.00451247794174135 0.996402996606811 TBX2 other 1 1 1 0.255900327403799 0.00451247794174135 2.27921106298087e-16 333.785705551479 39.2016063059709 8.51459256404599 1.18164836890008e-15 -29.6046924190737 87.2368222844338 -0.339360050536323 0.734602317448064 SLC35B1 essential 3.11887241858302e-12 1 1.74210419026938e-11 8.51459256404599 -0.339360050536323 0.820643643705014 -16.7652838132664 27.0426477010988 -0.619957187571732 0.535818688493654 -4.18080429706942 57.98672449618 -0.0720993353805462 0.942577240477256 TBX4 other 1 1 1 -0.619957187571732 -0.0720993353805462 0.0162036997273274 3.24208554857418 1.91500904063465 1.69298707200867 0.0915986830901762 -7.29517046510762 4.07825593661677 -1.78879662740331 0.0747562271004397 TEX14 other 1 1 1 1.69298707200867 -1.78879662740331 0.0336488825751427 46.3505135730005 35.0771356796256 1.32138821129352 0.187490584485746 -135.386149250603 78.0584812685185 -1.73441946410511 0.0839849772858086 FAM117A other 1 1 1 1.32138821129352 -1.73441946410511 9.65558532736701e-13 254.348367909288 33.3865622412023 7.61828564653468 4.60911119619318e-13 -100.059634056279 151.021847148218 -0.662550723261098 0.508196335931944 NCAPH essential 1.19082333842417e-08 1 6.5444769874747e-09 7.61828564653468 -0.662550723261098 0.672281127191513 -1.40490339028115 33.9364488443912 -0.0413980672144883 0.967008813620137 -37.3512109457388 50.3074794650381 -0.74245840465326 0.458447985364648 LRAT other 1 1 1 -0.0413980672144883 -0.74245840465326 2.97943330123537e-10 66.5923498972876 10.8071408330475 6.16188415844943 2.5800359423921e-09 18.3981994319773 15.9878930933198 1.15075822214902 0.250842349173905 MND1 other 3.31223600098336e-06 1 3.28180571872276e-05 6.16188415844943 1.15075822214902 0.00378391980509563 9.62007432751329 14.0750366333621 0.683484851805701 0.49488232250042 -46.5267815007076 21.3445416026712 -2.17979764413797 0.0301300875488565 TRIM6 other 1 1 1 0.683484851805701 -2.17979764413797 1.5480137468695e-06 10.0695773889053 4.68014315684417 2.15155328618095 0.0323467375352156 -22.9230787974285 8.24926992352898 -2.778800913284 0.00585089943245829 ABCC11 other 0.013582272615033 1 1 2.15155328618095 -2.778800913284 7.54394959733555e-17 89.6832293858331 17.2031639012267 5.21318229023199 3.72207814541753e-07 -101.234132351468 30.7839450513662 -3.28853667658736 0.00114229118776142 PAPD5 other 1.04453526124708e-12 1 0.00424800778736503 5.21318229023199 -3.28853667658736 0.00058950535692566 77.6450631199278 67.3969536224537 1.15205597503534 0.250328556934558 -290.280117222723 120.602473408694 -2.40691678220421 0.0167670970983273 ADCY7 other 1 1 1 1.15205597503534 -2.40691678220421 1.45279425544295e-24 229.387088779133 20.4593715908004 11.2118345258599 3.5410745892781e-24 -68.7924696952991 75.0150002151242 -0.917049516736913 0.359941191492156 CEP89 other 2.21870738691247e-20 1 5.51911885484885e-20 11.2118345258599 -0.917049516736913 0.712821561889158 12.3623824464335 16.3964480244923 0.753967104824597 0.451567350327075 28.4331351603179 59.028033525512 0.481688673366174 0.630441874501578 TSHZ3 other 1 1 1 0.753967104824597 0.481688673366174 1.29105955608042e-06 178.726611584724 77.856271251975 2.29559685701221 0.0224627922477105 -395.709572312192 136.65926792608 -2.89559265403232 0.00409278087374935 ECHDC2 other 0.0114026379993023 1 1 2.29559685701221 -2.89559265403232 0.619748026757154 63.5209118534505 81.7698329371237 0.776825750668887 0.437936614165087 -131.468335319825 341.715730723742 -0.38473012360707 0.700738015555255 PLBD1 other 1 1 1 0.776825750668887 -0.38473012360707 1.31334381294518e-14 191.036872412396 22.6542259951213 8.43272564039649 2.29178662450536e-15 73.5123361184448 103.190491708163 0.712394474544691 0.476854458078376 PYROXD1 essential 1.71627769475677e-10 1 3.36869715936042e-11 8.43272564039649 0.712394474544691 0.422403972001304 -10.3316093763037 15.0822214015484 -0.685019076516342 0.493937462408597 64.7944866242422 68.3072866706068 0.948573567805378 0.343711655143091 KCNJ8 other 1 1 1 -0.685019076516342 0.948573567805378 0.28688308152605 9.65232954914474 6.74119736058421 1.4318420056327 0.153337126805203 -9.90637172533353 29.5273609274354 -0.335498040264378 0.737508043516607 BCL2L14 other 1 1 1 1.4318420056327 -0.335498040264378 4.04057642561266e-10 215.19873446778 48.1924504526007 4.46540344902024 1.20310845836253e-05 -121.426911399751 72.3212261856494 -1.67899409072582 0.0943828942255527 PSPC1 other 4.46402883501687e-06 1 0.122753156006729 4.46540344902024 -1.67899409072582 0.000366142488270916 30.3931623931624 12.1740786496001 2.49654723515039 0.0131351372093571 -50.1784102836733 27.0130472597467 -1.85756200702489 0.0643158654007337 ZNF549 other 1 1 1 2.49654723515039 -1.85756200702489 0.02457176332139 20.2799404890686 9.93548285745578 2.04116304964988 0.0422215368586794 -22.4139844933578 24.0117997983304 -0.933457078669978 0.351430561467105 A1BG other 1 1 1 2.04116304964988 -0.933457078669978 0.675687269700611 40.8923791867484 52.8400336942291 0.773890104298219 0.439675373389935 88.6168326551109 127.279410171902 0.696238555281063 0.486880580191475 ZSCAN18 other 1 1 1 0.773890104298219 0.696238555281063 1.47613008448203e-07 32.1969453252195 12.1849669390768 2.64234983042629 0.00871574120524192 -99.8360385526388 27.1926984405116 -3.67142815087095 0.000290882026427872 ZNF211 other 0.00139759996398758 1 1 2.64234983042629 -3.67142815087095 0.583150331131685 -23.2563614502335 51.0275719784054 -0.455760690711984 0.648925712497235 -113.272742349487 109.008217089524 -1.03912113576228 0.299671216456906 PDZRN3 other 1 1 1 -0.455760690711984 -1.03912113576228 0.0316786740804904 11.562570663493 5.80568936140801 1.99159306392666 0.0474230781773992 33.5480214221957 17.7199362341526 1.89323601275363 0.0593956922994283 LHX4 other 1 1 1 1.99159306392666 1.89323601275363 7.32543377660642e-09 160.49093671919 26.5842173535457 6.03707585537721 5.12687492719195e-09 -134.494202499289 81.5756891698858 -1.64870445923169 0.100362679772122 RNF2 other 7.52468557533012e-05 1 6.44601984595844e-05 6.03707585537721 -1.64870445923169 3.64305810418418e-10 107.887041147435 15.7193552993835 6.86332480516335 4.5428635000899e-11 7.41325282508291 48.2360351181253 0.153687026865467 0.877970474773328 TRMT1L other 4.03213670971105e-06 1 6.13332001147138e-07 6.86332480516335 0.153687026865467 1.63643541262035e-17 133.705582885553 14.8738098977452 8.98932982233576 4.31770989354003e-17 -71.6750596852693 58.3656087666167 -1.22803584507912 0.220495108143859 SEC22A other 2.29771896286023e-13 1 6.46792942052297e-13 8.98932982233576 -1.22803584507912 0.0831602460388911 810.947766757582 417.612454252266 1.94186681575286 0.0531894180044816 -1274.8864831996 1643.01608307235 -0.775942789808624 0.43845940262045 CSTA other 1 1 1 1.94186681575286 -0.775942789808624 0.00714794562433345 6.79793440214337 2.68908375926739 2.52797421378774 0.0120408394184517 -14.6189231234605 10.2264061403311 -1.42952694454469 0.154004596418387 POPDC2 other 1 1 1 2.52797421378774 -1.42952694454469 4.77013621850671e-05 547.930029593137 121.648997518214 4.50418861455147 9.91167884475147e-06 649.556138402204 462.623022023047 1.40407223047764 0.161442304893557 B4GALT4 other 0.365917149321649 1 0.101822676772132 4.50418861455147 1.40407223047764 9.53884661071909e-22 1481.88835690675 144.557345004676 10.2512145395228 4.60201100348713e-21 -733.176293171543 554.724409363839 -1.32169466638822 0.187380393300453 NAA50 essential 1.42367285664982e-17 1 7.07835312446355e-17 10.2512145395228 -1.32169466638822 0.510025538785213 1.15481260613278 4.30555911706915 0.268214318914955 0.788738400225934 -17.4153397235733 16.3737540865406 -1.06361312326591 0.28845080868556 CD80 other 1 1 1 0.268214318914955 -1.06361312326591 1.24428916663142e-14 155.402390045067 21.005030178583 7.39834166977382 1.82354454878161e-12 -5.99924040109218 39.6649426352585 -0.151247928334564 0.879895215878847 KIF18A essential 1.62790351670388e-10 1 2.55405649502352e-08 7.39834166977382 -0.151247928334564 9.52796905715426e-09 352.403589628056 57.7313642490847 6.10419646602485 3.54820918540802e-09 -127.382617875189 156.487641730044 -0.814010719740645 0.416350853624901 DESI2 other 9.72424521973164e-05 1 4.49096836597093e-05 6.10419646602485 -0.814010719740645 0.205731220260443 48.7259842519684 71.0101797174732 0.686183085943924 0.493195326441979 -173.895991410165 151.181579418122 -1.15024589688418 0.251075638145707 MAPK8IP1 other 1 1 1 0.686183085943924 -1.15024589688418 0.00152863855289641 68.6107086614174 61.7323826129261 1.11142168433089 0.267390433839623 -338.963416845622 131.429030905121 -2.57906045955951 0.0104446647040345 CRY2 other 1 1 1 1.11142168433089 -2.57906045955951 4.99941887689337e-13 95.6857338000516 21.7991705522144 4.38942085300268 1.63865559400638e-05 -180.357668118045 46.3932532727695 -3.88758397816232 0.000127818798128769 PEX16 other 6.22677621117069e-09 1 0.165258416655543 4.38942085300268 -3.88758397816232 5.11195856845363e-06 50.6233514710307 10.3337210147747 4.89885022042414 1.67633134485721e-06 25.1255336728083 23.0031592008223 1.09226447782486 0.275705144185381 DEPDC7 other 0.0429046682650313 1 0.018290451303737 4.89885022042414 1.09226447782486 0.0389129525558642 253.037886674097 158.478415377307 1.59667097927286 0.111513117287078 -399.375844778336 363.366970390061 -1.09909781934671 0.272708105889524 CAT other 1 1 1 1.59667097927286 -1.09909781934671 2.83589677103495e-17 486.276438343915 109.885289695438 4.42530969970316 1.42821639834487e-05 -697.397871177072 165.055070648905 -4.22524354105142 3.32588593323338e-05 ZMYM2 other 3.96344932719845e-13 0.504703190368166 0.144764014136236 4.42530969970316 -4.22524354105142 0.000452095729566399 -220.105985496328 621.266069022575 -0.354286185052109 0.723413806069921 -3214.116866559 936.265197372694 -3.43291289217875 0.000695425163368345 GJB6 other 1 1 1 -0.354286185052109 -3.43291289217875 0.00852719864745282 42.7064639771104 21.3289826782443 2.00227383656095 0.046310066387849 -24.7974229117251 32.1272452238758 -0.771850270352362 0.440915024026989 GJA3 other 1 1 1 2.00227383656095 -0.771850270352362 7.12840589863542e-11 202.522195552213 34.9054560034547 5.80202119497219 1.85700486044803e-08 -230.205842659803 98.8858725932923 -2.32799525981448 0.0206625506015042 TBC1D15 other 8.16345043511728e-07 1 0.00022746452535628 5.80202119497219 -2.32799525981448 2.29907680777794e-05 228.753360014602 62.0209219286994 3.68832569560287 0.000273292408280941 -36.010597886401 88.155051613694 -0.408491597783911 0.683238996105404 ADGRB2 other 0.182436572617912 1 1 3.68832569560287 -0.408491597783911 7.59090157226795e-15 3.48648103309121 1.07283492181945 3.24978331911343 0.00130301093035855 -7.34917944578961 1.52668989589452 -4.81379975432637 2.48187544151629e-06 HCRTR1 other 9.99038555926184e-11 0.0386328731226425 1 3.24978331911343 -4.81379975432637 4.54318019639073e-17 119.131240369536 42.8868665021171 2.77780239233975 0.00585938546125116 -353.800260197778 61.5021933623917 -5.75264459452798 2.39311904908909e-08 ZCCHC17 other 6.32319819733662e-13 0.000379668337137984 1 2.77780239233975 -5.75264459452798 0.779409288368242 -9.41693017714764 18.8616179485372 -0.499264177804956 0.618002879882912 -18.7899744101468 27.0486274426515 -0.694673859144434 0.487861506249082 FABP3 other 1 1 1 -0.499264177804956 -0.694673859144434 1.89602131666141e-08 758.665204984261 182.893059534973 4.1481355657413 4.50386759382385e-05 -392.11924021346 259.959810362497 -1.5083840831653 0.132634195224073 KHDRBS1 other 0.000189924455289974 1 0.437190427332482 4.1481355657413 -1.5083840831653 5.55948102899411e-14 123.669229433683 24.1436617241592 5.12222341609161 5.77875004397647e-07 -88.8050043596084 34.3172219833117 -2.58776786777187 0.0101867491873604 TMEM39B other 7.14615691466903e-10 1 0.0065086061745307 5.12222341609161 -2.58776786777187 0.0204912835254221 -34.7184090744888 18.9373097855463 -1.83333374527079 0.0678416903051505 -129.077956795029 49.2208170463087 -2.62242613066718 0.0092209482152044 CCRL2 other 1 1 1 -1.83333374527079 -2.62242613066718 0.0391605933043367 -41.1799002962213 16.1299263124299 -2.55301230139455 0.0112239019470265 -28.3536594176717 41.9240198837806 -0.676310608960499 0.499416022712191 CCR2 other 1 1 1 -2.55301230139455 -0.676310608960499 0.232847792212825 23.6736426185371 15.747434823416 1.50333326563988 0.134000334218592 -41.7583910854066 53.3873935211936 -0.78217699593874 0.434841986706059 POLR3GL other 1 1 1 1.50333326563988 -0.78217699593874 0.0319266903151357 502.850686202566 191.07707291763 2.63166416841301 0.00900064950785865 -343.32385303683 1951.61165101578 -0.175918120215226 0.860494161161433 TNFSF10 other 1 1 1 2.63166416841301 -0.175918120215226 6.67685130515728e-44 332.800709511183 19.3154466007406 17.2297703692972 5.35271327653077e-45 229.728560937053 208.895258165174 1.09973085533328 0.272458855138473 ZNF639 other 1.0614858204939e-39 1 8.5156315516328e-41 17.2297703692972 1.09973085533328 0.185163422415093 4.18059898005516 2.53461591824366 1.64940137476611 0.100291915622164 -14.3172106540127 18.2895500092617 -0.782808250982802 0.434463251001454 SLITRK3 other 1 1 1 1.64940137476611 -0.782808250982802 1.33646042814563e-42 321.076721528671 19.1327423939669 16.7815316235019 2.0298438123292e-43 424.328399759287 206.946196116689 2.05042860280468 0.0413176251371445 PIK3CA og 2.12296739010933e-38 1 3.22826359912836e-39 16.7815316235019 2.05042860280468 1.66744183518344e-22 539.754076065958 121.416484954188 4.44547605104541 1.28353869058935e-05 -856.817867464105 180.499924548906 -4.74691537741862 3.36004727585622e-06 PDS5A other 2.50666531083126e-18 0.0521781741467713 0.13065140331509 4.44547605104541 -4.74691537741862 0.578413553947604 -15.3232493351334 31.0268308269416 -0.49387091516378 0.621795914547209 -51.2632520543011 49.7617598539645 -1.03017361533722 0.30384367399299 TMEM156 other 1 1 1 -0.49387091516378 -1.03017361533722 3.31850136501437e-17 47.5064662388112 9.03324988038734 5.25906698783519 2.94184882063012e-07 -40.1386671399701 14.5405211383192 -2.76046963916521 0.00616577682864433 LIAS other 4.63362345596957e-13 1 0.00338077266466814 5.25906698783519 -2.76046963916521 0.00545579647693269 815.785687768999 274.820815362614 2.96842757959438 0.00325993163482788 211.797061450826 383.591465371098 0.55214226741444 0.581304269327249 CPXM2 other 1 1 1 2.96842757959438 0.55214226741444 5.97728633368498e-08 -36.9737716094465 121.388304746148 -0.304590888609636 0.76091239992804 -891.615558802046 173.107916171167 -5.15063423165713 5.01302010251632e-07 TMEM54 other 0.000580514048727485 0.00787495327904289 1 -0.304590888609636 -5.15063423165713 4.3721715819322e-12 22.1946363009748 4.76381069883537 4.65900887002098 4.98612550993e-06 -18.0854562590556 6.85902212972318 -2.63673974467633 0.00885378674851352 ZSCAN20 other 5.25141528705877e-08 1 0.052453057403844 4.65900887002098 -2.63673974467633 0.445299916725881 -6.88875104372233 10.0265347934933 -0.687052026009304 0.49263963172578 -18.4447325223925 14.4797573582574 -1.2738288402239 0.203819516229553 CSMD2 other 1 1 1 -0.687052026009304 -1.2738288402239 3.08743545464623e-09 2.37628074019975 23.1922158476118 0.10246027183489 0.918467399699853 -178.327867056246 33.0736652527426 -5.39183866358623 1.52285824041334e-07 HPCA other 3.24335094510586e-05 0.00240337487502034 1 0.10246027183489 -5.39183866358623 0.000125150610928387 66.459589249633 30.0312462914185 2.21301469158887 0.0277238962446678 -65.3714190816241 44.130854130633 -1.48130872083546 0.139677571375054 LRIF1 other 0.915977321384862 1 1 2.21301469158887 -1.48130872083546 0.828556080716379 -4.10802113682012 6.99202206898916 -0.587529772687633 0.557333590677481 -2.38884215618674 10.2747619266437 -0.232496107767926 0.816326910917867 TMIGD3 other 1 1 1 -0.587529772687633 -0.232496107767926 2.56536726717298e-19 150.092451049691 39.3037287471199 3.81878401449861 0.000166285968942161 -284.483302036551 58.5784675554875 -4.85644834882508 2.02276012144964e-06 CLCC1 other 3.71285604577945e-15 0.031512579932064 1 3.81878401449861 -4.85644834882508 7.99746787627656e-16 267.423296705388 70.6107405971263 3.78728922036361 0.00018761777665103 -412.765026620113 105.238589543258 -3.92218318785474 0.000111262203425475 GPSM2 other 1.07981811265486e-11 1 1 3.78728922036361 -3.92218318785474 0.000186495951336524 35.2215357458076 20.4234710060116 1.72456169352605 0.0857637996514846 -136.170431719268 47.3113833300184 -2.87817480984264 0.00432335037990899 GTDC1 other 1 1 1 1.72456169352605 -2.87817480984264 0.811922990274776 129.366687387181 208.573255797401 0.620245807127076 0.535621052331337 200.296095178892 504.422681923442 0.397079874392508 0.691623424290003 CXCR4 other 1 1 1 0.620245807127076 0.397079874392508 6.95027878732003e-09 43.0400850897063 8.147407974726 5.28267213612238 2.63784616258544e-07 -25.961289527672 19.8204907845245 -1.30982072088458 0.191378146961197 ZRANB3 other 7.14905676063738e-05 1 0.00304328311777482 5.28267213612238 -1.30982072088458 0.175896222995045 42.0687941325187 30.7391066119139 1.36857569296479 0.172278060583046 -48.1129143491262 71.3440415059705 -0.674378873603619 0.500651761191771 ACVR2A other 1 1 1 1.36857569296479 -0.674378873603619 2.96174230697224e-09 38.425560678447 22.0013329728747 1.74651057396484 0.0818511063334065 -160.755291761417 34.6989438299705 -4.63285835295562 5.59812482722823e-06 POLK other 3.11604908116549e-05 0.0865470098289484 1 1.74651057396484 -4.63285835295562 0.846702690989302 -0.713997997550273 3.81611996688753 -0.187100511447657 0.851721824881189 -3.37440733014844 6.01301894114448 -0.561183552418044 0.57513614747829 FLT3 og 1 1 1 -0.187100511447657 -0.561183552418044 3.2717606124291e-10 106.762003250695 29.9820861501469 3.56085973190934 0.000436457522814875 -143.607075864051 47.0800658669809 -3.05027346966328 0.00251287057857881 RPL21 other 3.6293640473676e-06 1 1 3.56085973190934 -3.05027346966328 5.37826729260755e-15 74.5252855849127 22.5491078730121 3.30502146712901 0.00107768908841404 -175.164153731272 35.2002418228766 -4.97622018089186 1.15391827288432e-06 MTIF3 other 7.11114501428571e-11 0.0180484357061836 1 3.30502146712901 -4.97622018089186 5.09327054455792e-10 727.75191846332 162.401655461251 4.48118534504078 1.09599762219878e-05 -493.73787091615 253.516794405575 -1.94755488319354 0.0525008534750639 GTF3A essential 5.5934297120335e-06 1 0.112186316608267 4.48118534504078 -1.94755488319354 0.0230361170313089 111.902714448984 41.4534066950739 2.69948174035794 0.0073814412448355 61.6327578047659 65.0931728980195 0.946839047181261 0.344564294175824 RASL11A other 1 1 1 2.69948174035794 0.946839047181261 0.0011456482703582 211.952267787241 92.3979329358116 2.2939070285748 0.0225611250202725 -183.401647479032 145.391925488956 -1.26142938723899 0.208238916278806 UBL3 other 1 1 1 2.2939070285748 -1.26142938723899 3.97238785248227e-18 446.052734598908 47.87086527013 9.31783313466096 5.38337901648533e-18 -578.083544215115 346.276571610393 -1.66942724864891 0.0962409255067453 FYTTD1 other 5.63999627295432e-14 1 8.13374735600769e-14 9.31783313466096 -1.66942724864891 8.99819440317029e-13 71.2328119368042 25.8004717558216 2.76091121941331 0.00615915871092993 -197.778777881612 40.6497249695088 -4.86543950863049 1.94361391726577e-06 MTERF4 other 1.1109170810154e-08 0.0302912229005871 1 2.76091121941331 -4.86543950863049 0.123141977636804 6.88119494217057 3.69081876261262 1.86440878969077 0.0633413859018888 -0.718538383172548 6.88795895246078 -0.104318040820473 0.916993840227719 PAEP other 1 1 1 1.86440878969077 -0.104318040820473 4.81636090063791e-32 409.934303673866 38.0492049945999 10.7737941891833 8.94544169677231e-23 -273.891889417796 70.5379309880737 -3.88290222836427 0.000129635881854778 MRPS2 other 7.57469078843324e-28 1 1.3862750997488e-18 10.7737941891833 -3.88290222836427 0.537526492356113 -98.4006796518856 113.249333825541 -0.868885284601061 0.385675905504868 199.301077496892 323.023765311757 0.616985803829457 0.537760193176847 FMOD other 1 1 1 -0.868885284601061 0.616985803829457 0.0292903603948554 -26.5543889236461 10.0882383453731 -2.63221268318121 0.00896778527687086 7.10427241157325 29.6957057405851 0.239235681873822 0.811103000885794 LAX1 other 1 1 1 -2.63221268318121 0.239235681873822 3.09101962157614e-13 550.572715015278 88.9897309345967 6.1869241454379 2.23552067010388e-09 -246.695104894097 147.968606943439 -1.6672124580344 0.0966188784599445 KIAA1191 other 3.87675680938079e-09 1 2.85073595851646e-05 6.1869241454379 -1.6672124580344 9.15772944207734e-16 1398.74032880516 157.924935141325 8.85699479663199 1.07204357955569e-16 -21.3530310807939 590.40878026482 -0.0361665202052318 0.971176012170216 COPA essential 1.23501139255855e-11 1 1.60034665556073e-12 8.85699479663199 -0.0361665202052318 0.274983545154116 -1.34577657343944 3.28865648982201 -0.409217739099371 0.6827031083238 17.7349951567615 11.6016978275781 1.52865515205921 0.127516303129569 CD244 other 1 1 1 -0.409217739099371 1.52865515205921 0.727593795308846 -0.41667484090881 7.13794635339148 -0.058374610886622 0.953493257860993 19.9059798668415 25.1811938880832 0.790509773099435 0.429921335032323 LY9 other 1 1 1 -0.058374610886622 0.790509773099435 0.00941123916501493 -36.721802746306 19.8785608789304 -1.84730690365156 0.0657885356326568 -116.785491150212 38.1513819988742 -3.06110775105493 0.00242581869278878 HS3ST2 other 1 1 1 -1.84730690365156 -3.06110775105493 2.12519422037810e-11 279.955177779257 48.7632491008101 5.74111001505447 2.53417217961799e-08 -156.305782208457 103.92583054114 -1.50401282717277 0.133751211846032 RBBP6 essential 2.48838991264072e-07 1 0.000308408754259509 5.74111001505447 -1.50401282717277 1.46382765339106e-10 113.694271001207 31.4859790912944 3.6109491996913 0.000364084281388631 -209.796156930942 61.4332836796549 -3.41502430547141 0.000736592835285935 ZC3H7A other 1.65134397579045e-06 1 1 3.6109491996913 -3.41502430547141 3.4392589321197e-09 58.4782235512078 12.1338120142279 4.81944367381309 2.39217384698255e-06 -62.2521365319661 24.0298193560761 -2.59062024601634 0.0100950904907947 SERAC1 other 3.59952839835648e-05 1 0.0258019871135538 4.81944367381309 -2.59062024601634 8.33181209213674e-06 161.875945672913 288.470942916734 0.561151650270847 0.575161308235913 -1559.17351554608 439.895371851804 -3.54441900350648 0.000463849286634333 ANXA11 other 0.0686791270754832 1 1 0.561151650270847 -3.54441900350648 0.0401386889690961 -2.25624540636724 7.00603710038771 -0.322043028610623 0.747670222231437 -21.7531546168426 9.9926685529624 -2.17691145278642 0.0303567739277578 LDB3 other 1 1 1 -0.322043028610623 -2.17691145278642 1.22226531058462e-14 106.047707855929 29.0837132049345 3.64629189913536 0.000320209266827461 -154.82982191335 41.6702578630466 -3.7155954835272 0.000247263441249494 FAM35A other 1.59945638543103e-10 1 1 3.64629189913536 -3.7155954835272 4.19124390782969e-06 830.29573149255 216.794550372443 3.8298736295084 0.000159461002931477 -107.985639998782 329.834369861125 -0.327393534046342 0.743623951582023 FAM213A other 0.0354579234602392 1 1 3.8298736295084 -0.327393534046342 2.41619495643445e-11 75.4767169230302 14.7639306546907 5.11223729563172 6.01026400687485e-07 -44.3169740994254 26.5440743616527 -1.66956185759668 0.0961565131508529 ZNF205 other 2.82211570911544e-07 1 0.00676455213973764 5.11223729563172 -1.66956185759668 8.94129760432559e-12 181.864704848917 53.3289514028169 3.41024340559808 0.000747540148029688 -370.710331613989 95.6118717804066 -3.87724165117701 0.000132525461772355 NAA60 other 1.06240498134597e-07 1 1 3.41024340559808 -3.87724165117701 1.07372328598321e-14 4098.18427876708 709.34570932631 5.77741462996832 2.07109545675222e-08 -2436.89245863113 1140.99727746789 -2.1357565935995 0.0335923214047541 RPL5 other 1.40743648326679e-10 1 0.000253129286724256 5.77741462996832 -2.1357565935995 2.5015529773734e-11 82.7921680114695 38.7606110271739 2.1359871740264 0.0335700584001204 -323.37224209388 66.5349968511951 -4.86018272184035 1.98071691181197e-06 ODF2L other 2.92106341167892e-07 0.0308635309198541 1 2.1359871740264 -4.86018272184035 0.328278585482519 8.41262902593717 6.31927443640806 1.33126502268494 0.184224766459802 0.961746763524021 10.7618919605902 0.0893659560090284 0.928857331380517 PTGFR other 1 1 1 1.33126502268494 0.0893659560090284 6.7534422310543e-13 79.1217702799418 15.9101646408158 4.97303277911805 1.16910591631669e-06 -59.622387867259 25.4791299163342 -2.34004803394154 0.0200045816309017 TRMT13 other 8.37967112029217e-09 1 0.0128999146806383 4.97303277911805 -2.34004803394154 5.35025610729725e-10 13.9931878530572 3.71516057028932 3.76650957295433 0.00020293368405752 -15.6063006986866 5.94959643520008 -2.62308559389906 0.00920538721670337 LRRC39 other 5.86709084726217e-06 1 1 3.76650957295433 -2.62308559389906 5.3645321793504e-14 59.7759086444008 10.5450455300538 5.66862499303932 3.66827632387224e-08 -35.2937131630648 17.0761732386126 -2.06683972280504 0.0396954572204039 RWDD3 other 6.89664256977287e-10 1 0.000443054414397289 5.66862499303932 -2.06683972280504 3.99137180236589e-17 349.308453719908 44.2428308081729 7.89525551008324 7.31042446126639e-14 -25.294389579993 77.5165987613641 -0.326309332248466 0.744443111104735 ZNF644 other 5.56277488095735e-13 1 1.05087351630704e-09 7.89525551008324 -0.326309332248466 3.58303199751033e-18 67.5144148101141 10.4940656523965 6.43358037260764 5.59242886896818e-10 -44.5505394729003 16.9497762302734 -2.62838511067363 0.00906674826818287 CCDC18 other 5.09113016526243e-14 1 7.28749405915244e-06 6.43358037260764 -2.62838511067363 7.22970969541521e-19 121.796561334163 18.4968953473758 6.58470294861902 2.32977714568722e-10 -97.3523146503228 32.7257604618277 -2.974791518256 0.00319418777859182 RPAP2 other 1.03992144258852e-14 1 3.07647072087997e-06 6.58470294861902 -2.974791518256 1.83731956529138e-16 249.965595701716 54.1058232255526 4.61993886794175 6.11785066218174e-06 -354.227643155921 81.7064542964516 -4.33536917255881 2.10213726673495e-05 PQLC1 other 2.5184139281449e-12 0.320786146903754 0.0638887144651639 4.61993886794175 -4.33536917255881 6.0836676705323e-08 34.9959690833445 9.34842197045005 3.74351619920081 0.000221278650035793 -78.1691458460244 25.0625049454971 -3.11896779735374 0.00200909245120542 BBS9 other 0.000590480784101865 1 1 3.74351619920081 -3.11896779735374 1.07836086761416e-05 319.395771844834 121.389385152079 2.63116722639866 0.00899471912225687 -1129.28243212409 352.079099851076 -3.20746795990377 0.0014992192580114 ZMIZ2 other 0.0881020828840771 1 1 2.63116722639866 -3.20746795990377 4.31255193819054e-19 508.115717871147 75.4369621907932 6.73563334358606 9.63182568962886e-11 -910.561593908523 197.02556187179 -4.62154039941809 5.87990992835376e-06 SEPT7 other 6.22301244680894e-15 0.0908446083930656 1.28816036773096e-06 6.73563334358606 -4.62154039941809 0.0128881040533386 37.6903545482209 26.68246450113 1.41255147352017 0.158926611862176 -138.303830364609 69.6890146127972 -1.98458582221381 0.0481915513544043 EEPD1 other 1 1 1 1.41255147352017 -1.98458582221381 9.04390208602129e-17 185.862144627381 24.3601149425801 7.62977289169126 4.08642764040683e-13 -195.818966360954 68.9507199118168 -2.8399843629101 0.00485616822440561 KLHL7 other 1.24941507318384e-12 1 5.81049146189448e-09 7.62977289169126 -2.8399843629101 3.48203222178151e-21 155.899586525366 20.4746511072785 7.61427316678161 4.34869532928708e-13 -233.856330490172 53.4755048637516 -4.3731486235802 1.74360099143643e-05 HERPUD2 other 5.1666394106794e-17 0.266788387699689 6.17862632385109e-09 7.61427316678161 -4.3731486235802 4.1264144300363e-14 926.059255922339 136.212828008246 6.79861999389866 6.63566169551879e-11 -937.000883640948 380.878908335489 -2.46010178861259 0.0145095985955912 CBX3 other 5.32555046340485e-10 1 8.92363784813367e-07 6.79861999389866 -2.46010178861259 6.93355112747832e-05 1789.0283648643 471.097694839395 3.79757401588266 0.00018011343309197 -1365.82564994003 1317.08283474566 -1.03700816221159 0.300649696839388 HNRNPA2B1 og 0.523552445635888 1 1 3.79757401588266 -1.03700816221159 0.00381559188627135 108.004361201053 35.333899534961 3.05667822183591 0.00246072579994237 -36.6445791334616 96.8440977929683 -0.378387325284394 0.705438034488264 WIPF3 other 1 1 1 3.05667822183591 -0.378387325284394 0.518129491036398 27.618168919697 30.6000107148593 0.902554223822074 0.367564033300758 -36.7181547837193 87.0213167787763 -0.421944371136826 0.673400149414471 NPY other 1 1 1 0.902554223822074 -0.421944371136826 4.41438496564454e-08 242.653810176407 43.4381406067846 5.58619238270312 5.69643685148953e-08 -71.2648040731122 122.578661614363 -0.581380177712446 0.561472899846213 FAM126A other 0.000432344863535227 1 0.000682628081039167 5.58619238270312 -0.581380177712446 0.0435622347500825 37.6099865261499 14.9986103771269 2.50756473969786 0.0127418271174964 23.2567371054823 41.4548315224871 0.561013909629971 0.575251625019229 HOXA7 other 1 1 1 2.50756473969786 0.561013909629971 0.527206721439812 74.0100587711545 119.117053576644 0.621322107531261 0.534909981450546 -234.709988403737 334.052292860735 -0.702614511020843 0.482899101079813 INHBA other 1 1 1 0.621322107531261 -0.702614511020843 0.00196753808048191 1005.23172200163 386.945903734374 2.5978611281325 0.00989360565789219 -1579.56111203906 1043.71136495474 -1.51340798335328 0.131341399009948 FKBP9 other 1 1 1 2.5978611281325 -1.51340798335328 8.58076271792011e-10 145.072459675843 24.8488276062268 5.83820138216458 1.49433173756363e-08 -80.8003945171603 66.3839116648886 -1.21716832423264 0.224591295130767 NT5C3A other 9.30669524385615e-06 1 0.000184026953480961 5.83820138216458 -1.21716832423264 3.84376546453775e-05 207.822512157799 52.674002893417 3.94544748342587 0.000101438306933246 -195.144997876892 136.705550916204 -1.42748408216803 0.154587441509678 ARL4A other 0.297814948192385 1 0.95088268919225 3.94544748342587 -1.42748408216803 2.39495618931905e-14 256.654819739713 38.4601854037683 6.67326007519887 1.38980285141008e-10 -372.657331662759 102.443666652551 -3.63768053057557 0.000328851937075095 CCZ1 other 3.11009010744972e-10 1 1.84968861494168e-06 6.67326007519887 -3.63768053057557 0.735056489383541 -45.6133511232493 65.274162834909 -0.698796417176797 0.485276327451918 28.5567220227982 193.52171214973 0.147563401054986 0.882796663945367 RAMP3 other 1 1 1 -0.698796417176797 0.147563401054986 1.51643211869776e-15 206.282357863842 25.4734143706801 8.09794693644493 1.93303958772442e-14 -90.9535341923165 62.4829642876315 -1.45565331653641 0.146650211234555 MRM2 other 2.03383875759743e-11 1 2.80464713782936e-10 8.09794693644493 -1.45565331653641 0.398168430710018 27.796035678399 25.2264456281901 1.10186096321621 0.271507010427976 -32.2520399982498 68.2433383031692 -0.472603492152904 0.636879295931673 TWIST1 other 1 1 1 1.10186096321621 -0.472603492152904 9.36564591146852e-43 532.670369630701 44.8761383648442 11.8697906958945 3.08417797677612e-26 -475.677770011264 123.753792461259 -3.84374297183802 0.000152526977861172 SMU1 essential 1.48801382241412e-38 1 4.83167321841747e-22 11.8697906958945 -3.84374297183802 0.167867521212774 7.92166824017427 61.6865808609897 0.128418014576391 0.8979159478906 -272.819193094008 173.484717203932 -1.57258343842073 0.117012964352809 GLIPR2 other 1 1 1 0.128418014576391 -1.57258343842073 5.6142999175154e-29 97.7118533038632 9.51592581629683 10.2682445397508 5.22406389986675e-21 -52.8292076414119 22.9628566048452 -2.30063744030283 0.0221979308221922 SLC25A51 other 8.75999216129929e-25 1 8.03199824604513e-17 10.2682445397508 -2.30063744030283 1.79324031588252e-37 1524.80433975315 116.524072958264 13.0857452974486 1.70120399845035e-30 -178.859232049439 328.195853138055 -0.544977123687795 0.586229333397512 CLTA other 2.84085130842108e-33 1 2.68569075235357e-26 13.0857452974486 -0.544977123687795 0.0671202067881553 22.7483277075945 15.4376982940922 1.47355695611049 0.141792250180479 -35.3730344333196 43.6117317318052 -0.811089884044268 0.418044672460446 RECK other 1 1 1 1.47355695611049 -0.811089884044268 0.101833036236004 5.95353446510929 4.90098453097274 1.2147629578271 0.225571421737435 -12.367648484979 13.2225437618911 -0.935345626960528 0.350488242553025 TAF1L other 1 1 1 1.2147629578271 -0.935345626960528 3.79174712005328e-19 274.67988131043 41.1755485883009 6.6709464895502 1.54089002344968e-10 -363.516007861257 111.026024408933 -3.27415135141964 0.00120473343746468 ACO1 other 5.47566201606894e-15 1 2.04907555318338e-06 6.6709464895502 -3.27415135141964 0.000264091537053372 72.3940059127131 21.0155470096155 3.44478332539189 0.000664984558044489 -15.0639215094378 55.9949059348818 -0.269023070187065 0.788122853088691 PHF24 other 1 1 1 3.44478332539189 -0.269023070187065 0.703253909037607 -0.601994222800914 7.38857024647331 -0.0814764159667098 0.935125049609084 -15.1887500128689 19.9177581514032 -0.762573272424178 0.446401321615941 DNAI1 other 1 1 1 -0.0814764159667098 -0.762573272424178 7.74260954873553e-35 386.433746525091 33.064009194838 11.687443717062 1.16536221349088e-25 -195.945552662478 80.274910226789 -2.44093144556502 0.0153146610919689 DCAF10 other 1.22294517822278e-30 1 1.82379186411322e-21 11.687443717062 -2.44093144556502 0.000976144956712181 20.8684207935899 10.7625849971664 1.93897848881883 0.0535735697325658 -53.2257954437322 28.6763858326773 -1.85608450640528 0.0645599434310389 CNTFR other 1 1 1 1.93897848881883 -1.85608450640528 1.11770428832563e-08 303.921356667572 55.4746755877494 5.47856032410377 9.76853294800613e-08 -118.475822479939 154.222689538183 -0.768212659464778 0.44302728519722 KIAA1549 other 0.000113514047522351 1 0.00115551976241964 5.47856032410377 -0.768212659464778 3.07370484625811e-10 304.536068346127 52.1509253003729 5.83951419063219 1.48917239362755e-08 -170.009249919974 144.55456515782 -1.17609049381708 0.240587029195616 TRIM24 other 3.41488608419276e-06 1 0.000183406471999169 5.83951419063219 -1.17609049381708 8.39165304803489e-24 272.268343014853 31.4281429431745 8.66320175223666 4.1598592726535e-16 -292.630162767579 83.7436496756885 -3.4943564544994 0.00055459064603406 C7orf49 other 1.27519559717938e-19 1 6.17198320283600e-12 8.66320175223666 -3.4943564544994 0.569117078636403 -265.83206901091 250.937923178897 -1.05935390571235 0.290378447306324 -326.71112318254 668.650946606511 -0.488612369189994 0.625509857600176 CALD1 other 1 1 1 -1.05935390571235 -0.488612369189994 0.693151774850143 -10488.3673861473 17111.9857229448 -0.612925206692046 0.540441717593613 -22104.4580763363 26057.101070849 -0.848308413750035 0.397017655052283 SFTPA1 other 1 1 1 -0.612925206692046 -0.848308413750035 0.579479455339052 -5.23098960355343 9.79925947931874 -0.533814786167607 0.593905653301109 -15.9678173352646 15.4033980945471 -1.03664251467456 0.300823193999279 NEUROG3 other 1 1 1 -0.533814786167607 -1.03664251467456 0.00539955781332833 1489.23408897529 761.841060635911 1.9547831771265 0.0516443177023107 -1067.86382156077 1191.82149337516 -0.895993089146802 0.371057544785823 PLAU other 1 1 1 1.9547831771265 -0.895993089146802 0.820256279865975 368.546069394161 639.455321818657 0.576343736331711 0.564859468444641 152.296398606798 1000.52978742175 0.152215756613552 0.879129612077134 SRGN other 1 1 1 0.576343736331711 0.152215756613552 0.00105807019168373 180.976223634871 100.528351012902 1.8002505941 0.0729289560639146 -224.979226313155 157.592193065994 -1.4276038802185 0.154552966938157 CHST3 other 1 1 1 1.8002505941 -1.4276038802185 0.974690499119423 -7.73728031735784 34.4379210369696 -0.224673269592893 0.822404663768197 -5.95493334563397 51.3424462772298 -0.115984604891625 0.907751603477602 BICC1 other 1 1 1 -0.224673269592893 -0.115984604891625 1.1860367166347e-06 160.298394272413 40.6440364138298 3.94395853404632 0.000102301295803934 -28.7417636486848 61.0232438554588 -0.470996981359486 0.638024609585331 CISD1 other 0.0105035411625169 1 0.958665442978668 3.94395853404632 -0.470996981359486 0.929016682849093 -16.7906774070626 95.4181681311689 -0.175969395932867 0.86045038260568 -54.2635073294336 143.324857675104 -0.378604997134835 0.705279842829365 EGR2 other 1 1 1 -0.175969395932867 -0.378604997134835 6.84985046186648e-24 167.51346893594 24.6320554540599 6.80062893039364 6.67889583278293e-11 -113.831281471155 38.5368565017092 -2.95382892650071 0.00341512838368146 ECD essential 1.04172525824065e-19 1 8.97843966801009e-07 6.80062893039364 -2.95382892650071 4.58676295192272e-07 1184.99824457519 240.281669918503 4.93170471545796 1.42611842371473e-06 405.603461799343 375.920728617643 1.07896008632152 0.281568454447646 P4HA1 other 0.00420055751137083 1 0.0156445191081506 4.93170471545796 1.07896008632152 3.39724192769796e-07 79.0930883909674 23.5445197946287 3.35929927986941 0.000893620814564117 -54.5893177708184 36.3769781961583 -1.50065564754863 0.134608803364479 SLC25A16 other 0.00314584602504831 1 1 3.35929927986941 -1.50065564754863 2.16028368302985e-08 509.458367920313 99.3255847042198 5.12917562415989 5.58780184492305e-07 69.072987529041 147.140632426686 0.469435168178015 0.639140309074054 ZWINT essential 0.000215596311566379 1 0.00629745267922828 5.12917562415989 0.469435168178015 1.99118810815463e-19 494.2795765918 82.5518538233294 5.98750426186207 6.71571046646278e-09 -352.83357068099 129.165535009106 -2.73163867324294 0.00671432406146509 VPS26A other 2.88702363801339e-15 1 8.39866750935836e-05 5.98750426186207 -2.73163867324294 0.01306192537976 238.060824034198 127.932492913884 1.86083158869143 0.0638508872318023 -467.894080022065 272.130052780946 -1.71937672903294 0.0866876108815077 RBM19 essential 1 1 1 1.86083158869143 -1.71937672903294 0.00100166923752468 58.5429258816115 19.8481238423991 2.94954456887021 0.00346026484149922 -57.3024405933585 42.4142005956972 -1.35102017221967 0.177815841324917 IFT81 other 1 1 1 2.94954456887021 -1.35102017221967 0.0736090032385617 27.3176925133807 21.8315105785954 1.25129648793813 0.211901454458155 -65.1875039903814 45.554634138453 -1.43097415275598 0.153585500442366 ACADS other 1 1 1 1.25129648793813 -1.43097415275598 0.807504554028298 -6.92437277975145 22.0945876958792 -0.313396786356095 0.754219412797917 -30.5302231349913 47.5745454074644 -0.641734416451221 0.521586063754033 HVCN1 other 1 1 1 -0.313396786356095 -0.641734416451221 6.27540726582416e-10 527.116808402521 96.4993082313775 5.4623895037532 1.06350912565449e-07 -482.249337923728 203.848891636061 -2.36571969586524 0.0186992046852252 DDX54 essential 6.8590201415458e-06 1 0.00125557887374769 5.4623895037532 -2.36571969586524 0.000248151884119499 293.995518260829 116.792498173323 2.5172465942507 0.0124027448622693 -615.468205623432 248.454213575503 -2.47718964700269 0.013850122755792 MED13L other 1 1 1 2.5172465942507 -2.47718964700269 0.00564027281649869 -5.87256871423597 43.6286932619344 -0.13460336020102 0.893026894945534 -191.844649501837 69.2900928614105 -2.76871687682036 0.00602201558276533 CDKN2C other 1 1 1 -0.13460336020102 -2.76871687682036 6.30997028750627e-09 217.701224031344 121.006841499441 1.79908194721659 0.0731348638221996 -781.069500808467 192.180298273515 -4.06425376495582 6.34258184286014e-05 RNF11 other 6.50810335453397e-05 0.953353476800308 1 1.79908194721659 -4.06425376495582 0.0175370682841664 85.7943632890499 33.6192268898393 2.55194337365859 0.0112699462194795 356.085219243205 202.33580253172 1.75987252274536 0.0795745343882193 RASSF8 other 1 1 1 2.55194337365859 1.75987252274536 0.710731268845076 -28.4246315273256 37.7710024524899 -0.752551684670784 0.452379845225364 -109.583283564335 228.960259821102 -0.478612679990656 0.632604423109345 BHLHE41 other 1 1 1 -0.752551684670784 -0.478612679990656 0.730817140736621 12.2684445679644 17.2847142677834 0.709785789796435 0.47845407815702 50.9395783627699 106.346066325516 0.478998237761313 0.632330468896867 SSPN other 1 1 1 0.709785789796435 0.478998237761313 0.00594245556158443 77.1504657291414 24.4320551544301 3.15775587610166 0.00177100342589927 -13.4990175540148 153.086116578844 -0.0881792409115195 0.929799825730759 ITPR2 other 1 1 1 3.15775587610166 -0.0881792409115195 6.91963888489099e-10 248.589946919126 37.1437264356169 6.69264962819547 1.25481592675415e-10 91.2056807794086 228.414056017095 0.399299773270444 0.689986824359042 CCDC91 other 7.54586620397362e-06 1 1.67279511195596e-06 6.69264962819547 0.399299773270444 0.525914835720154 14.4828892265318 13.5367463591652 1.06989440758236 0.28562590251767 -3.45595062747126 47.1433234737975 -0.0733073184666775 0.941616047474713 NECAB1 other 1 1 1 1.06989440758236 -0.0733073184666775 7.44970437255839e-13 253.768179364337 37.9851310990375 6.68072406286278 1.36947384214473e-10 -244.168220834154 128.235027737794 -1.90406806269354 0.0579722227332685 WWP1 other 9.22645886541357e-09 1 1.82345442081571e-06 6.68072406286278 -1.90406806269354 5.65177101549326e-20 666.010576972114 83.2789108891815 7.99734974750532 3.75002964694115e-14 -510.133228743487 206.347380252733 -2.47220598642289 0.0140448758923005 DDX39A other 8.25836780783875e-16 1 5.41391780128893e-10 7.99734974750532 -2.47220598642289 1.08049607233471e-05 527.601997173854 114.931948936628 4.59055991006267 6.79145317439448e-06 108.928360400219 285.162451637368 0.381987038527568 0.702772567802642 PKN1 other 0.0882549191882991 1 0.070705818998621 4.59055991006267 0.381987038527568 0.658968380543081 -1.49184645010923 129.366805326255 -0.0115319107273839 0.990807618220585 264.07047721438 319.58411924616 0.826294115731637 0.409369548641519 ADGRE5 other 1 1 1 -0.0115319107273839 0.826294115731637 7.66295830809785e-28 197.268379888107 19.8857274520606 9.92009874236031 5.59573967775594e-20 -101.013288869594 44.4192336730962 -2.27408895914328 0.0237456455918458 WDR83 other 1.19028731399684e-23 1 8.5681965945799e-16 9.92009874236031 -2.27408895914328 4.02963900839008e-09 588.515400697377 141.93974349945 4.14623407220442 4.53435402490883e-05 -975.57752673259 351.028120796137 -2.779200494023 0.00583348299273711 GIPC1 other 4.19968977454414e-05 1 0.439832340416156 4.14623407220442 -2.779200494023 2.5518478424327e-10 91.9409440087462 21.4338932823044 4.28951207313566 2.4876396859797e-05 -90.4003321880775 34.479124977973 -2.6218859163575 0.00923520951897343 SPRYD7 other 2.84684145301792e-06 1 0.247296261183242 4.28951207313566 -2.6218859163575 5.31626289041828e-12 209.098576302558 41.6838344302961 5.01629898401534 9.50179053844983e-07 -164.818727927055 67.0537133853262 -2.45801044574398 0.0145924808921905 EBPL other 6.36462993240876e-08 1 0.0105564892882178 5.01629898401534 -2.45801044574398 0.00276496402206055 64.4925189570694 25.5334100879589 2.52580907661382 0.0121114217526716 -37.2219687156899 41.7101275977067 -0.892396424069833 0.372969288915841 ATP7B other 1 1 1 2.52580907661382 -0.892396424069833 4.41671457479644e-12 398.545590328829 75.3759374396023 5.28743792603811 2.55692105181264e-07 -243.584058748939 119.238414969908 -2.04283207563949 0.042036515094478 ZC3H13 other 5.30226584704312e-08 1 0.00295222104642287 5.28743792603811 -2.04283207563949 0.000214611761794664 10.8700249405847 4.7136027299217 2.30609696306868 0.0218573462159899 -15.0071761351862 7.71885337639588 -1.94422350100313 0.0528994075231724 GUCY1B2 other 1 1 1 2.30609696306868 -1.94422350100313 3.44291493772716e-06 305.722296791559 62.7058055927582 4.87550225854791 1.85823567314075e-06 115.420170425921 99.2428261175998 1.16300769477435 0.245857032564642 NLN other 0.0292992061200581 1 0.0202213205951176 4.87550225854791 1.16300769477435 2.11099618305847e-12 147.406552280056 20.7786936372083 7.09412029715359 1.13637323372606e-11 36.3196107784431 32.9219482140891 1.10320356931064 0.27091744847487 CENPK essential 2.57077115172861e-08 1 1.56114954849286e-07 7.09412029715359 1.10320356931064 3.24504388851399e-12 83.9348829529119 102.017415313378 0.822750534260056 0.411370574167785 -997.744418716079 171.888721580018 -5.80459502836901 1.79322930778658e-08 OPTN other 3.9206620261026e-08 0.000284603423438808 1 0.822750534260056 -5.80459502836901 0.371494205693274 -119.721072592384 214.120840623236 -0.559128538090525 0.576535757458166 -500.819030477952 363.218505426504 -1.37883676904037 0.169082099753678 ITIH5 other 1 1 1 -0.559128538090525 -1.37883676904037 1.00582589670521e-09 107.293395459535 23.3414180595636 4.59669567571857 6.57886217049892e-06 -173.123727236921 59.3892520496613 -2.91506832064756 0.0038520822605645 ATF1 other 1.0863925510313e-05 1 0.0685912169896218 4.59669567571857 -2.91506832064756 1.5336885251916e-13 176.891416673801 25.7074887589935 6.88092945725462 4.08936306447471e-11 -114.977049676528 66.6384176413427 -1.72538685260131 0.0855935579341911 TSFM essential 1.9434900991228e-09 1 5.52759205425047e-07 6.88092945725462 -1.72538685260131 0.364640537511274 -33.1070276654705 23.5672582346738 -1.40478910765959 0.161220788195724 -43.0482726116386 63.1173391125491 -0.682035605697448 0.49579467371715 ARHGAP9 other 1 1 1 -1.40478910765959 -0.682035605697448 0.272644684458795 -123.753493885791 83.5043950450651 -1.48199976562916 0.139493700618316 29.6634402303401 225.820841337133 0.131358292948944 0.895588631171242 NCKAP1L other 1 1 1 -1.48199976562916 0.131358292948944 0.944778854806812 -15.9812707674392 85.4637748251637 -0.186994674645868 0.851804210112193 46.2979078411001 228.74675010373 0.202398101044519 0.839756817312554 MMP19 other 1 1 1 -0.186994674645868 0.202398101044519 0.0124125725275448 738.325640818983 319.965329888464 2.30751763347721 0.0217741420445119 -861.826251264919 861.30807493573 -1.00060161554764 0.317905508493497 PFDN5 other 1 1 1 2.30751763347721 -1.00060161554764 4.55155369727076e-08 174.571506474072 40.8206298845791 4.27655102255098 2.63022536174087e-05 -258.421080998821 104.130231592864 -2.48171042209157 0.0136795872451103 SPATS2 other 0.000445415044814916 1 0.260918355884695 4.27655102255098 -2.48171042209157 4.24629073711203e-07 148.166359318085 35.7624821127637 4.14306699548699 4.57938020191175e-05 -203.844966429543 95.7195206468789 -2.12960705456886 0.0341019970349401 ORMDL2 other 0.0039002180420374 1 0.443925116773325 4.14306699548699 -2.12960705456886 0.815035933277353 262.724963625152 457.11490859709 0.574745996431114 0.565936417698455 -71.3423875569167 1193.13858364846 -0.0597938818965698 0.952363545319765 NR4A1 other 1 1 1 0.574745996431114 -0.0597938818965698 0.591563243220666 -7.91236544139024 8.53492433486818 -0.927057479474707 0.354715540994587 2.67665469291642 23.080986252383 0.115967951440553 0.90776319943356 PDE1B other 1 1 1 -0.927057479474707 0.115967951440553 0.351804948482008 7.75825064120248 16.7478106279695 0.463239692252424 0.643563000819067 -52.7550791918016 45.9534638960088 -1.14801093800425 0.251972709394503 HOXC13 other 1 1 1 0.463239692252424 -1.14801093800425 6.90003749678817e-09 308.407189119918 54.232578230452 5.6867513804967 3.33685340738179e-08 -111.223625269867 144.371533447203 -0.770398586301237 0.441732106694678 CDK2 essential 7.09944858044535e-05 1 0.000403725893759122 5.6867513804967 -0.770398586301237 0.351474421887061 -925.881433698271 641.02673958211 -1.44437256127858 0.149780901502454 -1010.29595012038 1716.78443455456 -0.588481541296426 0.556695668668921 LRP1 other 1 1 1 -1.44437256127858 -0.588481541296426 0.0900277067617323 21.4253428874694 11.5145529499298 1.86071860372139 0.0638629242934113 -16.2639978544745 31.5941949080559 -0.514778043935136 0.60712617763999 HOXC11 other 1 1 1 1.86071860372139 -0.514778043935136 5.37044179835271e-10 227.768859485254 46.9402888872676 4.85231056059895 2.05448653024647e-06 -335.474530772058 122.521205818665 -2.73809361024875 0.00658594834576754 ATG101 other 5.88815238771391e-06 1 0.0222788519339927 4.85231056059895 -2.73809361024875 0.643267012567988 -6.51559703284113 7.15532551641706 -0.910594076802215 0.36331850642993 -1.46745287462507 19.6286545676616 -0.0747607468238148 0.940460229431746 NFE2 other 1 1 1 -0.910594076802215 -0.0747607468238148 0.0116069661635126 23.9287028258232 8.7678822912205 2.72913139467938 0.00676419262397271 -7.61917374601966 24.0577452936548 -0.316703566897817 0.751711470757123 HOXC12 other 1 1 1 2.72913139467938 -0.316703566897817 0.0195515419223096 18.8169359907908 10.2263586337486 1.84004264515933 0.0668554727653533 -39.4955566371986 27.4713975659148 -1.437697392076 0.151673612871149 IKZF4 other 1 1 1 1.84004264515933 -1.437697392076 2.13774784735092e-10 165.809932121313 31.6616041792384 5.23694033892444 3.27266352537868e-07 -228.841101168329 86.8746618206031 -2.63415242571979 0.00891800394607094 SMUG1 other 2.39478466867156e-06 1 0.00374981786737889 5.23694033892444 -2.63415242571979 2.91138146380342e-10 6720.37908257222 1013.89500746136 6.62827909508996 1.81797370477558e-10 1206.26832224601 2601.7574273631 0.463635967580796 0.643279374049199 TUBA1B essential 3.23832960218854e-06 1 2.41099672727337e-06 6.62827909508996 0.463635967580796 9.38456708456e-06 14.3357140236519 9.62048409097038 1.49012397797188 0.137350303239815 -97.363481270408 24.9380187530646 -3.90421878475985 0.000119281144733539 EEF1AKMT3 other 0.0770942185996604 1 1 1.49012397797188 -3.90421878475985 3.27174714677866e-11 103.042403317365 22.5555688638879 4.5683797176288 7.47110767073495e-06 -146.496173959125 48.2738240443262 -3.03469171666633 0.00264181335530519 KBTBD4 other 3.80144300984213e-07 1 0.0774977998685336 4.5683797176288 -3.03469171666633 0.547986437669149 9.16143603672756 9.37132122279612 0.977603458351421 0.329135977706489 -1.42440199580762 17.6697757794103 -0.0806123412990566 0.935809314857583 SARDH other 1 1 1 0.977603458351421 -0.0806123412990566 6.49259628273636e-11 270.729079435039 49.9968360431934 5.41492424042894 1.34845668412057e-07 -97.1262554853897 87.962229498407 -1.10418137465636 0.270490309991538 ATPAF1 other 7.4496049748117e-07 1 0.00158308814715755 5.41492424042894 -1.10418137465636 6.6469614557748e-11 156.251450245816 30.237371836077 5.16749442024551 4.61861090981675e-07 -75.4432961753375 52.8362164689925 -1.4278709040344 0.154484635911837 STIL essential 7.62074130904581e-07 1 0.00523565732736827 5.16749442024551 -1.4278709040344 1.31137460233489e-08 247.641273584905 52.2069523582642 4.743453934746 3.39050620228806e-06 -67.6375402015437 79.9107132554036 -0.846413921815045 0.398063192096918 HJURP essential 0.000132579972296057 1 0.0361427961163908 4.743453934746 -0.846413921815045 0.313282161848092 -155.640185626897 118.076566948986 -1.31812932615275 0.188565261880974 48.3789598511515 214.258964697216 0.225796665822217 0.821528518272917 COL10A1 other 1 1 1 -1.31812932615275 0.225796665822217 0.000265114232568347 302.926050589266 104.058214438957 2.91112097418286 0.00390069479925123 -307.0722135132 195.334849204512 -1.57202984907061 0.117110388288608 AMD1 other 1 1 1 2.91112097418286 -1.57202984907061 7.49066703727809e-09 112.22660628615 20.7298848778796 5.41375926336689 1.37137773109302e-07 -34.7728936836339 38.1112516668129 -0.912404924079519 0.362375613866303 NDUFAF4 other 7.69160069489792e-05 1 0.00160903749189144 5.41375926336689 -0.912404924079519 5.42076936721083e-11 51.1614943013282 9.91106595922625 5.16205769508594 4.76450348801802e-07 -46.3615073312434 18.0618858170621 -2.56681432940121 0.0108072163632749 USP45 other 6.24201592634327e-07 1 0.00539437084913401 5.16205769508594 -2.56681432940121 2.22741079641048e-20 230.27699861225 24.2195561206308 9.50789508549639 1.09964501496025e-18 -34.4863968416084 70.6485764169658 -0.488140010607868 0.625845389882915 METTL8 other 3.27095275452879e-16 1 1.67058070672761e-14 9.50789508549639 -0.488140010607868 3.98791824515701e-10 113.109423758908 18.3098580388003 6.1775150587852 2.37611011418111e-09 -16.8261092538207 44.1344002733342 -0.381247035183731 0.703318672497099 TTC21B other 4.40744724454753e-06 1 3.02621384142106e-05 6.1775150587852 -0.381247035183731 0.0336024236869965 83.7304820095043 37.7522877644191 2.21789160254333 0.0273977505867317 -44.4073493829096 88.1505148746693 -0.503767328484095 0.614837195652878 NMI other 1 1 1 2.21789160254333 -0.503767328484095 0.189873384634192 -38.6388323150034 24.7379205939611 -1.56192725125149 0.119480785389692 -83.7556878514108 57.7623388255053 -1.45000513404468 0.148222006247351 TNFAIP6 other 1 1 1 -1.56192725125149 -1.45000513404468 7.31683917038139e-05 74.3275232808631 17.2323541099466 4.31325417332045 2.25281718089979e-05 24.3996329773289 45.9454422775273 0.531056656935549 0.595812881550258 ACVR1C other 0.550592147571199 1 0.224673457451136 4.31325417332045 0.531056656935549 2.57904478206254e-05 50.562485288348 16.6463014107997 3.03746063708449 0.00261758780696521 -97.3390512619327 43.5636010793375 -2.23441241885996 0.0262684707389639 BAZ2B other 0.203486633304734 1 1 3.03746063708449 -2.23441241885996 0.0391381495706468 113.208211215558 46.8437451739019 2.41671990135044 0.0163170655877974 30.4223085895755 78.1719145706469 0.389171849719527 0.697452409417629 SLC36A1 other 1 1 1 2.41671990135044 0.389171849719527 0.0077708490582111 202.9469566449 73.0639846848477 2.77766066989484 0.00585609247650122 -225.990723935569 200.262014024382 -1.12847523798525 0.2601136133006 LPGAT1 other 1 1 1 2.77766066989484 -1.12847523798525 0.188836749922426 7.80073580781829 5.50149711449394 1.41792963723763 0.15735590520366 20.294120587877 15.0058688802503 1.35241222949687 0.177366750253837 BATF3 other 1 1 1 1.41792963723763 1.35241222949687 0.24673187565525 142.951085837301 91.6636660183128 1.55951744073537 0.120054027037506 -106.467788717077 251.950718072507 -0.422573864966868 0.67294503556435 G0S2 other 1 1 1 1.55951744073537 -0.422573864966868 0.056166087619065 93.3398575895774 40.6054543185432 2.298702456506 0.0222830509850112 -11.107886592912 87.2768608993955 -0.127271839046963 0.898819632691448 KCNJ2 other 1 1 1 2.298702456506 -0.127271839046963 6.05218176586342e-17 240.94475925604 35.7606337341048 6.73770943343914 9.74419887784154e-11 -66.5256703024509 53.479676662909 -1.24394301636812 0.214603412762478 EXOSC9 essential 8.39679698195891e-13 1 1.30279938996741e-06 6.73770943343914 -1.24394301636812 9.97077974143992e-17 128.84674820816 28.9392199234914 4.45232278371016 1.2460023540281e-05 -175.678748136754 45.5336767009378 -3.85821573976116 0.000143033869435737 PLA2G12A other 1.37556877312905e-12 1 0.126955179851923 4.45232278371016 -3.85821573976116 4.76013633846451e-10 25.3176270243498 4.44732773070879 5.69277295431403 3.22292042783491e-08 -24.0266091334052 13.4902191317658 -1.7810392031979 0.0760178573987624 B9D2 other 5.23614997231097e-06 1 0.000390327893015086 5.69277295431403 -1.7810392031979 8.94659482451642e-24 217.150945233044 21.5688599845114 10.0677989188571 1.79941867716633e-20 -216.727473966717 89.5866749186596 -2.41919319099069 0.0162113273203408 COQ8B other 1.35898775384404e-19 1 2.76030825077315e-16 10.0677989188571 -2.41919319099069 0.0303349194450007 87.9223092916668 33.7261650354823 2.60694654133271 0.00963752346092994 -25.715093008175 96.0176337738366 -0.267816358282118 0.789042911601179 PFKFB2 other 1 1 1 2.60694654133271 -0.267816358282118 0.287855001596773 -193.437050347088 199.476131290904 -0.96972529542891 0.333048112760551 638.786035403697 558.878146902629 1.14297908934877 0.254056000792844 C4BPA other 1 1 1 -0.96972529542891 1.14297908934877 0.571488475974539 -6.33429723694298 6.10973461027088 -1.03675489051433 0.300770901469894 1.93147885211479 17.345333187467 0.111354381679471 0.911417458218116 C4BPB other 1 1 1 -1.03675489051433 0.111354381679471 1.95754200206872e-05 220.342674688437 76.8179102868867 2.86837631830308 0.00445161148951236 -314.686910686453 157.605753723493 -1.99667146187154 0.0468647513633013 RAB38 other 0.15638803054527 1 1 2.86837631830308 -1.99667146187154 0.173685468087926 25.6768802158461 14.9111348501575 1.72199369624606 0.0862201619469579 6.63372455109066 26.5800886089631 0.249574959989174 0.803106537756854 GPR83 other 1 1 1 1.72199369624606 0.249574959989174 3.18498249509178e-08 356.61652498599 62.6598030594487 5.69131257319224 3.27951080814265e-08 -204.501108266296 245.787529006432 -0.832023939916594 0.406130702195584 AGO2 other 0.00031477181998992 1 0.000397017578433749 5.69131257319224 -0.832023939916594 6.70903060407279e-14 425.412864928142 65.9963451975037 6.44600642134094 5.23552273212941e-10 -215.216913171622 124.009445223836 -1.73548807337342 0.0837911232933012 CKS2 other 8.59829362217969e-10 1 6.83131006088245e-06 6.44600642134094 -1.73548807337342 0.48189588726503 -0.732076118635326 6.22881154870598 -0.117530625691736 0.906525998615048 -10.131853248757 9.38876502832556 -1.07914653505436 0.281474921033953 DAW1 other 1 1 1 -0.117530625691736 -1.07914653505436 1.11465284825195e-09 340.331873347221 118.140019164724 2.88075011121077 0.00428322536176175 -613.427666330137 173.95840559825 -3.52628931163478 0.000494414759700262 ACSL3 other 1.20059258285218e-05 1 1 2.88075011121077 -3.52628931163478 0.00407448248619212 191.247581197961 361.964246000071 0.528360420432031 0.597684822604471 -1340.47741514996 537.554600129853 -2.49365816016856 0.013244518303065 CHPF other 1 1 1 0.528360420432031 -2.49365816016856 9.07931669875256e-17 319.338858111859 64.2507852293375 4.97019385789616 1.18965376030437e-06 -365.35421039089 95.328659573162 -3.83257471600649 0.000157809587853795 DNPEP other 1.25405584021846e-12 1 0.0131218809761572 4.97019385789616 -3.83257471600649 0.490511032140809 -15.8947251449284 32.8016416835786 -0.484571025385164 0.628374991891186 -57.51342842481 48.7138538506794 -1.1806380296066 0.238789429486673 INHA other 1 1 1 -0.484571025385164 -1.1806380296066 2.32056383087073e-06 380.273696393991 146.444924067011 2.59670110669035 0.00993010863970094 -520.704997921121 217.485962958544 -2.39420048465553 0.0173416703946409 OBSL1 other 0.0200380686795687 1 1 2.59670110669035 -2.39420048465553 0.827982546747305 -2.07253101227615 5.82165475708342 -0.356003765038528 0.722114723451451 -5.21747764796194 8.49951921805753 -0.613855621018801 0.539825671313602 FAM124B other 1 1 1 -0.356003765038528 -0.613855621018801 0.000730958518433508 155.689211226946 77.0838243031967 2.01973906502832 0.0444018517182585 -228.792648067869 138.476696433204 -1.65221047267134 0.0996583738464 SLC12A4 other 1 1 1 2.01973906502832 -1.65221047267134 4.61126948592584e-06 37.7203762801143 15.5825611406873 2.42067885629041 0.0161515458602374 -64.746680540274 27.4740644382652 -2.35664732772834 0.0191552693505904 ENKD1 other 0.0388960581137844 1 1 2.42067885629041 -2.35664732772834 0.0106910631468381 236.346454795376 78.276556820783 3.01937724900828 0.00277444429207472 293.040630934508 242.080169222773 1.21051068278475 0.227137697449664 CTCFL other 1 1 1 3.01937724900828 1.21051068278475 2.74285530683396e-07 655.014341669171 140.580142242216 4.65936604716617 4.98603207260875e-06 -763.381149712997 426.113133994164 -1.79149875658011 0.0743331338487677 FAM210B other 0.002552226863009 1 0.052453057403844 4.65936604716617 -1.79149875658011 0.567698347084806 -913.146100965638 904.384534085634 -1.0096878778327 0.313542195047849 -1857.1673363914 3090.50728892338 -0.600926373171043 0.54838945092367 PI3 other 1 1 1 -1.0096878778327 -0.600926373171043 1.37736181556516e-24 78.1320924335489 8.11077742698749 9.6331200229432 4.53839875279005e-19 -91.2174209557999 25.0777977248268 -3.63737765001173 0.000329854060745799 FAM209A other 2.10392017327578e-20 1 6.91016594099813e-15 9.6331200229432 -3.63737765001173 1.78841056229929e-11 99.7552721627616 16.9227493608527 5.89474381707293 1.11640474048002e-08 -142.264285948553 56.1037417479973 -2.53573614728881 0.0117855057965431 SNX21 other 2.10209777492659e-07 1 0.000138344875440284 5.89474381707293 -2.53573614728881 0.127964814915048 -250.19069879757 568.632976664645 -0.439986263661809 0.660296463644858 -3946.97661387193 1942.40615766068 -2.03200375900035 0.043124981328129 SLPI other 1 1 1 -0.439986263661809 -2.03200375900035 0.354572697099178 2.47049381036596 4.89623593756822 0.50457000885316 0.614270895026883 -18.5195302226454 16.0378635481831 -1.15473798408414 0.249214946110987 WFDC3 other 1 1 1 0.50457000885316 -1.15473798408414 1.55214346827058e-19 241.754112322538 26.4507952229639 9.13976726539599 1.49643581860115e-17 -160.366829728379 91.1936137131012 -1.75853136199756 0.0797816918494299 TTPAL other 2.25402274462253e-15 1 2.2522855505766e-13 9.13976726539599 -1.75853136199756 0.134870085141096 89.6093951885801 68.6519275253246 1.30527136554942 0.192915802645182 -248.083500481964 221.231505046481 -1.12137509723057 0.263128266317039 PREX1 other 1 1 1 1.30527136554942 -1.12137509723057 0.579146828818817 7.66506757007377 7.70217999871519 0.995181568251117 0.320532454538237 15.2916352411215 26.3202681265392 0.58098326231345 0.561732815046305 KCNS1 other 1 1 1 0.995181568251117 0.58098326231345 9.28051830815929e-05 17.34607676934 4.87567734274488 3.55767528283047 0.000441540426885555 -23.0631804595576 16.204674827847 -1.42324241026575 0.155816092138942 SLC12A5 other 0.690748977676296 1 1 3.55767528283047 -1.42324241026575 0.0162484080330808 30.6515324280432 11.2154386431563 2.73297669429514 0.00669093919265352 66.3761382876136 40.8265583533906 1.62580783109535 0.105157133621848 ARHGAP40 other 1 1 1 2.73297669429514 1.62580783109535 0.0283659113172653 1134.65110274541 572.932028729072 1.98042882200597 0.0486628135096218 -2360.87794674295 1957.09138617315 -1.20631972703092 0.22874241820962 SDC4 other 1 1 1 1.98042882200597 -1.20631972703092 4.26907596220366e-10 484.198716894037 87.1138802562676 5.558226949249 6.53799348731474e-08 -659.205631767457 283.027025145386 -2.32912610175242 0.0205904375060697 NCOA3 other 4.70665624832953e-06 1 0.000780113382906395 5.558226949249 -2.32912610175242 2.97087085631973e-12 815.691617236101 122.108923427273 6.6800328292299 1.34337308450653e-10 -740.68977760716 417.114614354017 -1.77574640666633 0.0768927318126271 PIGT other 3.59415956197561e-08 1 1.7893729485627e-06 6.6800328292299 -1.77574640666633 0.139593476168374 -12.5456721938091 13.3973857934673 -0.93642688112531 0.349884112721151 65.692307956911 45.7644310648798 1.43544465490633 0.152309355915258 MATN4 other 1 1 1 -0.93642688112531 1.43544465490633 1.73475391485911e-10 201.71913979776 32.2325829893068 6.25823688609381 1.51504807533135e-09 -125.873276581784 107.127377282365 -1.17498700868975 0.241031263263114 NCOA5 other 1.95003687569313e-06 1 1.94486721430286e-05 6.25823688609381 -1.17498700868975 5.93304600924992e-21 385.464021992539 43.4009210885477 8.88147099933905 9.17819286058111e-17 -403.977284311362 131.01897409735 -3.08334946975848 0.00225733083786917 VAPB other 8.77794157068525e-17 1 1.37113023144221e-12 8.88147099933905 -3.08334946975848 0.0369887720032309 28.2915126170037 17.1095138335524 1.65355444299785 0.0993802297060054 -82.3729162418682 56.8141885887451 -1.44986522359991 0.148256685977912 PARD6B other 1 1 1 1.65355444299785 -1.44986522359991 2.81818946678707e-12 809.348178406373 141.923376767797 5.70271224401995 3.06934416362523e-08 -1440.09673723196 421.841563953186 -3.41383320253331 0.000738162610972948 ATP5E essential 3.41254562533246e-08 1 0.000372127286397923 5.70271224401995 -3.41383320253331 3.24581027554692e-10 464.01922408847 73.9883927120149 6.27151377506703 1.42624424543441e-09 -276.287801714991 256.667459143981 -1.07644265711145 0.28269737960448 CHD6 other 3.60155108174687e-06 1 1.83357960193047e-05 6.27151377506703 -1.07644265711145 1.51295732925723e-12 741.148137834907 99.2992816925644 7.46378146147662 1.20023078366351e-12 -28.3427971778724 344.214607617941 -0.0823404833804476 0.934437887920342 PLCG1 other 1.8527675454084e-08 1 1.68848466645782e-08 7.46378146147662 -0.0823404833804476 0.00208291927869844 41.7388689459137 19.3833712928454 2.15333381976333 0.0321714892189001 -145.542964484086 67.1679465161307 -2.16685148248701 0.0311143207016328 TOX2 other 1 1 1 2.15333381976333 -2.16685148248701 9.34100440852031e-10 553.455297589828 91.7350035344468 6.03319644918315 5.25768684215449e-09 -412.478864317146 317.331207048317 -1.29983706347022 0.194761343547834 SRSF6 other 1.01060326695781e-05 1 6.60786082321976e-05 6.03319644918315 -1.29983706347022 9.83453041800628e-14 344.270481460316 50.9311759912999 6.75952350911992 8.51685004243951e-11 -451.437440825006 165.583323947738 -2.72634604779097 0.00682310984046192 ARFGEF2 other 1.25380428299162e-09 1 1.14066172618392e-06 6.75952350911992 -2.72634604779097 0.000763606031917241 129.031036178435 67.6086479323467 1.90849898828846 0.0573910656349577 -600.930728734063 222.42531910622 -2.7017190810327 0.0073365551402559 ZNFX1 other 1 1 1 1.90849898828846 -2.7017190810327 0.417755371847821 -10.6610420507601 9.83301156586936 -1.08420924549351 0.279232114505087 -29.8616500181327 29.2215686072996 -1.02190441654365 0.307734159079069 ZNF831 other 1 1 1 -1.08420924549351 -1.02190441654365 0.80254791761311 33.0628986107128 57.6137165704952 0.57387199748271 0.566528643562651 -28.5780398843305 171.215416579996 -0.166912772548015 0.867562699881735 EDN3 other 1 1 1 0.57387199748271 -0.166912772548015 2.74059661911303e-16 1040.37631357122 125.416466042083 8.29537258067958 5.19288633408613e-15 -520.82742343355 407.659970720695 -1.27760256302032 0.202487015186884 CSE1L essential 3.74338092204649e-12 1 7.59875057266824e-11 8.29537258067958 -1.27760256302032 8.71623042082106e-16 595.619380736696 81.4838361684516 7.30966298034093 3.03863081239391e-12 -815.358660556785 271.201970856968 -3.00646288808427 0.00289195309686897 TMEM189-UBE2V1 other 1.17608097068139e-11 1 4.23554748939587e-08 7.30966298034093 -3.00646288808427 3.2228875581832e-16 259.189597337047 40.6201818711299 6.38080839124116 7.55336276412588e-10 -545.098533646636 122.624461023421 -4.4452675191985 1.279554125221e-05 RAB22A other 4.39537405185025e-12 0.196462740386432 9.80124352272975e-06 6.38080839124116 -4.4452675191985 0.103901038200508 -103.779427926358 85.6307738363743 -1.21194079274191 0.226594554504276 387.332695904095 282.469542586619 1.3712370273879 0.171439660765411 PTGIS other 1 1 1 -1.21194079274191 1.3712370273879 1.06333233677418e-22 842.454897328069 89.5877871389307 9.40368016928032 2.41453703716383e-18 -910.541596545484 291.213577468243 -3.12671409232208 0.00196162788485946 STAU1 other 1.60116583271456e-18 1 3.65754070389578e-14 9.40368016928032 -3.12671409232208 0.0324164559790823 74.4891461503231 42.4575876953822 1.75443660823963 0.0804859160923012 -182.006997784515 127.483896502935 -1.42768618450822 0.154533514581632 CDH26 other 1 1 1 1.75443660823963 -1.42768618450822 0.478954877016729 11.5045747322374 10.7486944942997 1.07032298092933 0.285433369791298 -9.94134125059888 35.4695705703952 -0.280278026791124 0.779479627596657 SNAI1 other 1 1 1 1.07032298092933 -0.280278026791124 1.08193712818575e-17 94.8727427537516 11.1953921911839 8.47426701392934 1.57482069060278e-15 -72.7272590201156 37.4381891170365 -1.94259553507679 0.0531084921850083 MOCS3 essential 1.52401663876245e-13 1 2.31860850277447e-11 8.47426701392934 -1.94259553507679 3.2292135772268e-11 560.147145090998 90.159163399458 6.21286981789324 1.94335679234364e-09 -536.205359142094 271.355277545603 -1.97602701518116 0.0491620946023827 STX16 other 3.75363786216844e-07 1 2.48535900172828e-05 6.21286981789324 -1.97602701518116 0.0150493922276098 388.295543702652 231.781692919826 1.67526407634345 0.0950316168316287 -1315.56535062072 709.060309049876 -1.85536453504716 0.0646259576074313 PMEPA1 other 1 1 1 1.67526407634345 -1.85536453504716 3.81559728228504e-12 310.332735438735 54.8825203277617 5.6544913314004 3.98685754052442e-08 -630.560965897217 181.106591956731 -3.48171184209499 0.000581222195303958 RNF114 other 4.59932096406638e-08 1 0.000480735282236435 5.6544913314004 -3.48171184209499 5.77910430933983e-23 570.47019318581 56.4731537627115 10.1016174089162 1.50323312967643e-20 -350.053485815823 185.7907180628 -1.8841279557222 0.0606259968725085 DDX27 essential 8.72298004451754e-19 1 2.30686156080145e-16 10.1016174089162 -1.8841279557222 0.334306773175097 -3.0674625591353 24.1886450385966 -0.126814154089272 0.89918118704115 -106.443481637002 73.0208340808262 -1.45771385628354 0.146073017047384 C20orf85 other 1 1 1 -0.126814154089272 -1.45771385628354 0.0316686542041492 -79.4077537406593 85.1991499251283 -0.932025188167271 0.352159254897186 -743.765246192015 282.146613982548 -2.6360948858951 0.00887383906943168 BCAS4 other 1 1 1 -0.932025188167271 -2.6360948858951 3.44812093587257e-07 24.9043159122474 4.46954225535782 5.57200592127608 6.05392688564561e-08 13.7906632816374 15.2735395152461 0.902912076658558 0.367371461702754 KCNK15 other 0.00319123592615006 1 0.000724049655523215 5.57200592127608 0.902912076658558 5.05852785315425e-08 3.97594310221704 0.880017483008239 4.51802740171222 9.31502307698093e-06 -7.62331292817466 3.00607148721935 -2.53597193565956 0.0117735742917561 TP53TG5 other 0.000493459392075197 1 0.0959167926236726 4.51802740171222 -2.53597193565956 0.840171416945322 -16.1352275262664 44.5551852227876 -0.362140286154934 0.717528393848642 -74.9867091817381 136.703361938711 -0.548535954919362 0.583773893974845 PCK1 other 1 1 1 -0.362140286154934 -0.548535954919362 0.00136314962078039 -23.7468314239874 7.47883766239628 -3.17520348695183 0.00166954562357308 -60.8463842523526 22.8843703348983 -2.65886206882271 0.00830522645292777 ZBP1 other 1 1 1 -3.17520348695183 -2.65886206882271 3.08336398746664e-10 12.5139388440053 2.04564470027462 6.11735695955673 3.32808402310957e-09 -8.70095596262358 6.78189575021769 -1.28296810848859 0.200603447418096 NEURL2 other 3.42500071727794e-06 1 4.21701526568213e-05 6.11735695955673 -1.28296810848859 7.89897344096043e-24 68.425314589299 6.03578501279518 11.3366056684002 1.2642950426986e-24 -12.9578649697125 35.874186198548 -0.361203036021398 0.718230141882341 FASTKD3 other 1.20072295276039e-19 1 1.97280598462689e-20 11.3366056684002 -0.361203036021398 1.49193758891782e-10 306.451390397598 47.0561872402954 6.5124568812319 3.69354779447558e-10 -128.40526560368 157.774146746192 -0.813854920161556 0.416458746949742 PEPD other 1.68245801902263e-06 1 4.84519599679306e-06 6.5124568812319 -0.813854920161556 0.288110066837213 -0.489250272885584 2.76467654791066 -0.176964742315091 0.859671260799155 13.6740945506758 9.31274260253568 1.46832089474401 0.143203045067599 CHST8 other 1 1 1 -0.176964742315091 1.46832089474401 1.12568084965828e-12 306.951544573264 39.3131201422504 7.807865248614 1.27641009859485e-13 106.965927422395 172.507767747451 0.620064411122584 0.535736415075318 STAMBP other 1.38413717273982e-08 1 1.82858510724698e-09 7.807865248614 0.620064411122584 0.129937381388616 111.246629859028 57.8086985639656 1.92439256759834 0.0553446863010237 -139.30101254369 262.112202639353 -0.531455655787829 0.595535214945429 NAGK other 1 1 1 1.92439256759834 -0.531455655787829 0.0862611163779965 13.8389204132111 6.35841419573359 2.1764735651378 0.0303770364111386 -9.60791087277337 28.2895727607502 -0.339627287906719 0.734398359938093 MCEE other 1 1 1 2.1764735651378 -0.339627287906719 0.00013391337914624 70.6857035397592 17.2265655701882 4.10329634492471 5.38221095106043e-05 -79.9474398794799 76.8687032738905 -1.04005188684684 0.299236020571949 PAIP2B other 0.977032014250966 1 0.518468380915651 4.10329634492471 -1.04005188684684 8.29877736631595e-13 147.449457649064 18.7827374948774 7.85026451491844 9.69554517360586e-14 8.45954969867296 88.0746416528921 0.0960497770971649 0.923552027623527 SNRNP27 essential 1.0260608335713e-08 1 1.39160159876765e-09 7.85026451491844 0.0960497770971649 1.32065725594943e-07 168.688636694311 31.361694044956 5.37881137583004 1.61287906491291e-07 340.691858410758 139.533049951429 2.4416570735704 0.0152551862875023 MPHOSPH10 essential 0.00125462439315196 1 0.00188432661153775 5.37881137583004 2.4416570735704 0.0183744838176705 33.9786018288095 73.0634761405068 0.465055916084064 0.642267648731015 -195.119155821167 107.433318226968 -1.81618848827653 0.0704545356511683 ATP8A1 other 1 1 1 0.465055916084064 -1.81618848827653 5.37736913246116e-19 1616.7377230358 221.353879841833 7.30385988350883 3.07649437430666e-12 -880.250621093028 545.405446728065 -1.61393808289545 0.107696079553622 USP22 other 7.75147760444276e-15 1 4.2877102094712e-08 7.30385988350883 -1.61393808289545 0.0998010849903505 87.5815455473608 42.552372775392 2.05820591978855 0.0405265072454037 26.5344280537207 105.333779417124 0.251908060268529 0.801303062907376 HIF3A other 1 1 1 2.05820591978855 0.251908060268529 2.74634388090029e-24 85.3363600164929 9.44007124291858 9.03980042317028 2.98030219634322e-17 -87.7349617373069 25.9923282162246 -3.37541758504504 0.000844059955011114 ZNF576 other 4.18817441837293e-20 1 4.47075132473447e-13 9.03980042317028 -3.37541758504504 3.06817897757398e-18 69.7954615659389 9.18275291385899 7.60071214162811 4.74177072540474e-13 -76.4875670398484 25.4907732279765 -3.00059815195806 0.00294353840843725 ZNF45 other 4.36693913878105e-14 1 6.7295210134944e-09 7.60071214162811 -3.00059815195806 0.292542799888055 55.6687367243717 353.858742096498 0.157319094038917 0.875110089185033 -1458.71018744551 1040.62464397675 -1.40176402306892 0.16212580763926 LYPD3 other 1 1 1 0.157319094038917 -1.40176402306892 0.243275721716713 -2.1901132213537 2.98305454567644 -0.734184771957317 0.463482799565779 -15.1201711270757 9.04845548328953 -1.67102232585431 0.0958933212993715 CEACAM8 other 1 1 1 -0.734184771957317 -1.67102232585431 0.19148024747401 -144.065005506821 95.6958231814068 -1.50544716286856 0.133386815021015 -266.649481922484 173.080935423519 -1.54060573609686 0.124592646155852 F13A1 other 1 1 1 -1.50544716286856 -1.54060573609686 0.256857456471589 11.9757313483827 20.7306982408948 0.577681041382319 0.56395737357298 -46.7488960316044 39.4467466901939 -1.18511410836386 0.237006721032419 GRM4 other 1 1 1 0.577681041382319 -1.18511410836386 0.000113402847094934 86.676924074995 25.4351940218599 3.40775556893735 0.000754485919372699 -76.3314132229019 57.843672461142 -1.31961561178847 0.188077103838682 TRERF1 other 0.834871760312905 1 1 3.40775556893735 -1.31961561178847 0.00643915968955065 25.3756613343955 10.003453730109 2.53669002916646 0.0117479548218918 -14.63868315279 19.0357092114944 -0.769011702697722 0.442551150758376 PACSIN1 other 1 1 1 2.53669002916646 -0.769011702697722 0.354102867710742 46.1574944555308 38.5042036706311 1.19876507122097 0.231666500823628 -19.5342926802154 67.1578657099654 -0.29087125497076 0.771372269536656 BTN2A2 other 1 1 1 1.19876507122097 -0.29087125497076 2.07626156186612e-11 152.258192394463 21.8344559358226 6.97329912144324 2.34821823263408e-11 13.835434695532 41.3776507323708 0.334369749143544 0.738358237044738 SIRT5 other 2.43296329819472e-07 1 3.19686430190803e-07 6.97329912144324 0.334369749143544 1.64975427243374e-12 269.901366862186 38.8291914025313 6.95099117733857 2.74038930390281e-11 -57.8978604302865 67.5607320831394 -0.856975030392478 0.392221488163454 MRS2 other 2.01748449975923e-08 1 3.72336694721274e-07 6.95099117733857 -0.856975030392478 2.50864741153074e-16 424.502624830927 61.3787624002035 6.91611574151779 3.44662863779115e-11 -296.620374772648 110.477114601085 -2.68490334712031 0.00771085221988006 WRNIP1 other 3.42982274104483e-12 1 4.66914781561568e-07 6.91611574151779 -2.68490334712031 7.42946747435561e-28 307.731042429267 27.3439224313073 11.2540928684369 2.23929913495043e-24 -100.907622373201 66.5814137706407 -1.51555241408371 0.130793794831407 RRP36 other 1.15431636149063e-23 1 3.4924109308687e-20 11.2540928684369 -1.51555241408371 0.0229722620385536 6.38780311574797 4.07361088521743 1.56809358962792 0.118026163385795 -10.7702400253771 7.10506871208853 -1.5158530426388 0.130722048521477 BTN2A3P other 1 1 1 1.56809358962792 -1.5158530426388 1.96127125605421e-23 666.763842132091 67.423134882534 9.88924414881837 6.57124885033544e-20 -126.284001236738 128.300407477098 -0.984283711330218 0.325847547839797 SNRPC essential 2.97211046142455e-19 1 1.00579534903234e-15 9.88924414881837 -0.984283711330218 0.0248282836122278 213.490213845358 115.254080820626 1.85234407602122 0.0650841958665508 -232.957629328567 207.44859943642 -1.12296554405018 0.262464656782737 SERPINB6 other 1 1 1 1.85234407602122 -1.12296554405018 1.56018930836991e-34 963.774920503132 71.1265027832849 13.5501519516523 2.89951834777804e-32 -84.0668801163363 173.583532628653 -0.484302161865669 0.628564053529978 XPO5 essential 2.46291484219274e-30 1 4.58413850783708e-28 13.5501519516523 -0.484302161865669 5.59716274636968e-14 280.318861766944 37.189336424573 7.53761396994762 7.27307598296648e-13 -64.7758435672807 90.6952373568589 -0.714214389366521 0.475711604256406 ABCC10 other 7.19403327790895e-10 1 1.02746744411368e-08 7.53761396994762 -0.714214389366521 5.85695603405397e-06 142.962556828477 35.5855576969003 4.01743196063301 7.62667218426845e-05 -130.021280572346 86.7577038739019 -1.49867129680294 0.135122866552406 PEX6 other 0.0488704411481463 1 0.724533857505503 4.01743196063301 -1.49867129680294 1.35540505924362e-07 237.481825054295 42.6426433590845 5.569115944678 6.25863061439894e-08 55.3365137293278 76.7535221149909 0.720963835984277 0.47156491633666 NQO2 other 0.00128641494172812 1 0.000747656013196098 5.569115944678 0.720963835984277 5.81215418133173e-25 513.464164355993 48.5466180455268 10.5767236736135 4.10001986147987e-22 -100.789463200572 103.658104750464 -0.972325930936152 0.331755483645623 PRICKLE4 other 8.89840805161888e-21 1 6.33658069591715e-18 10.5767236736135 -0.972325930936152 1.69717371150395e-24 213.305153659807 20.042163477901 10.6428207660816 2.35375602802206e-22 -17.0091823912455 41.8162626188424 -0.406759985852518 0.684502987187368 OARD1 other 2.59124482272424e-20 1 3.64149595095292e-18 10.6428207660816 -0.406759985852518 0.0556360728928945 2.92931812233451 22.4195598805998 0.130659037819441 0.896141265065812 -102.680245716133 46.6359916792715 -2.20173822875459 0.0285203515582892 UNC5CL other 1 1 1 0.130659037819441 -2.20173822875459 5.51836205665318e-27 267.491326038561 23.8589488778169 11.2113625545031 3.43805184959463e-24 -61.0623104610631 55.2931673002014 -1.10433736106198 0.270433659169926 AARS2 essential 8.54076895508212e-23 1 5.35923522314811e-20 11.2113625545031 -1.10433736106198 1.71650522109569e-06 45.1670979475756 9.74637728292825 4.63424476976591 5.5720806374282e-06 -9.00264903732109 16.9670951746936 -0.530594597639113 0.596134263492947 ZNF391 other 0.0150074051480396 1 0.0583954050802475 4.63424476976591 -0.530594597639113 3.52762467018181e-10 963.037016899297 158.625043654559 6.07115367606469 4.23727423067813e-09 -147.391664275826 301.849769703078 -0.488294771338776 0.625733034176346 RPS10 other 3.90613879729232e-06 1 5.34574516942352e-05 6.07115367606469 -0.488294771338776 0.0516841374175127 14.166161850939 23.9856879101481 0.59060894580161 0.555271072983316 -99.6516445005785 49.9498743693214 -1.99503293569409 0.0470332204629363 MOCS1 other 1 1 1 0.59060894580161 -1.99503293569409 0.0586160306168818 36.265719030259 15.182791556904 2.38860679173113 0.017597077958228 20.5017110354288 26.4311407085329 0.775665010508236 0.438623162574312 HIST1H2BJ other 1 1 1 2.38860679173113 0.775665010508236 5.85216552810752e-37 248.702312605754 17.9441120117347 13.8598283628141 2.20281064780051e-33 -36.6123902843724 40.5298796963019 -0.903343176903461 0.367146048613749 MED20 essential 9.26573368065264e-33 1 3.48726953653299e-29 13.8598283628141 -0.903343176903461 1.0270979402103e-22 165.675359759197 16.8917042865636 9.80809022870371 1.29861420803931e-19 -55.3881396018539 37.9225252610368 -1.46056042472366 0.145303087260538 TBCC essential 1.54691220775073e-18 1 1.98480195556728e-15 9.80809022870371 -1.46056042472366 0.305887356188035 54.3297722341223 48.8663522067948 1.11180331210742 0.267200863309319 -49.1921233172427 92.9884513820687 -0.529013254722602 0.597226109491527 SPDEF other 1 1 1 1.11180331210742 -0.529013254722602 5.58567261601107e-29 208.846797801075 17.066951332686 12.2369129512369 1.09223818528097e-27 2.17780227996859 41.6517273815006 0.0522860014909214 0.958339469878366 MAD2L1BP other 8.71588355002368e-25 1 1.71623386053199e-23 12.2369129512369 0.0522860014909214 1.81987041756294e-15 648.654453351693 85.0379579245104 7.62782255340038 4.02460636156827e-13 -314.071243790882 207.064201451199 -1.51678195260084 0.130483064902741 KLHDC3 other 2.43536982012385e-11 1 5.72379516742239e-09 7.62782255340038 -1.51678195260084 0.788990368164717 -40.1199516081145 59.2527930458678 -0.677098066534307 0.498917079731767 -46.1225152258659 124.935112332903 -0.369171759360711 0.712285869498472 TREM1 other 1 1 1 -0.677098066534307 -0.369171759360711 3.07175276649798e-37 837.601564562282 57.597443092481 14.5423393746384 7.72206789708539e-36 80.7583148736794 140.247588849237 0.575826761346269 0.565208386942854 MEA1 other 4.86473485630285e-33 1 1.22471996847774e-31 14.5423393746384 0.575826761346269 1.55600055609686e-12 34.8108170813989 4.67405961201759 7.44766219752438 1.35155146990724e-12 4.86387873281881 10.9194736690022 0.445431609641243 0.656372908280864 KLHL31 other 1.90485588077377e-08 1 1.89879466007268e-08 7.44766219752438 0.445431609641243 0.0409882469366207 82.9448911788891 54.5168593538167 1.52145395318122 0.129347326218554 318.12499514489 131.824535662447 2.4132457098843 0.0164953097944658 COL21A1 other 1 1 1 1.52145395318122 2.4132457098843 0.129707094323513 -115.978634680199 254.240737997195 -0.456176439676157 0.648628463859945 -1000.36011619375 499.141584890648 -2.00416103661831 0.046047800094664 CDKN1A other 1 1 1 -0.456176439676157 -2.00416103661831 0.000611295407953772 1722.61093968989 470.771262181007 3.65912509550672 0.000304709433581367 -60.0674731516345 856.027755822146 -0.0701700064549245 0.944110677540681 SOX4 other 1 1 1 3.65912509550672 -0.0701700064549245 7.66390735317251e-22 1615.07853661729 157.025007713922 10.2854861154329 3.65240723744975e-21 215.824684070323 328.311740557538 0.657377295444295 0.511496280263698 GLO1 other 1.14491111949044e-17 1 5.61959377554019e-17 10.2854861154329 0.657377295444295 0.0234414568501501 -44.5390495295321 16.7728901467777 -2.65541890155936 0.00839002420167906 -9.78968834620893 32.9296045826916 -0.297291402987407 0.766471799206802 CPNE5 other 1 1 1 -2.65541890155936 -0.297291402987407 0.262942563332745 5.09023144256407 4.22275863051837 1.20542798865566 0.22908190599802 -5.17957838504131 8.79996749486696 -0.58859062696113 0.556622576968993 KCNK17 other 1 1 1 1.20542798865566 -0.58859062696113 0.00293825654613894 55.9732948991721 65.9936227803741 0.848162179025245 0.397107368729219 -326.854885703436 119.479156170685 -2.73566449729943 0.00664272914739746 RREB1 other 1 1 1 0.848162179025245 -2.73566449729943 3.94796900163681e-11 811.323625611465 167.493893049524 4.84389974368543 2.15584919379023e-06 -926.431757609765 302.744411459026 -3.06011183871234 0.00243701352862783 SSR1 other 4.57253769769575e-07 1 0.0233262882768102 4.84389974368543 -3.06011183871234 8.7472228752796e-10 213.445333470743 41.3555235771854 5.1612291420364 4.7837230202326e-07 -144.89525679819 74.7499112833499 -1.93840038483717 0.0536243901994562 RIOK1 essential 9.48286431909061e-06 1 0.00541565283120533 5.1612291420364 -1.93840038483717 0.135156010278699 230.054436299744 115.979900408775 1.98357159722426 0.0483239939497266 103.217444254913 209.204855744513 0.493379773082155 0.622148323303638 NRN1 other 1 1 1 1.98357159722426 0.493379773082155 8.18412974248263e-05 36.5061098965407 18.519549141907 1.97122022878694 0.049719760292918 -95.6789568016391 33.3528511350288 -2.86868898896479 0.00444734568747006 SLC35B3 other 0.613155000306799 1 1 1.97122022878694 -2.86868898896479 2.64423741869915e-11 69.7271901273746 10.6190301170538 6.56624845760587 2.66481713616802e-10 -7.79820733634036 19.1149962668809 -0.40796279672059 0.683626714178798 RPP40 essential 3.08318083020321e-07 1 3.5114295403286e-06 6.56624845760587 -0.40796279672059 0.000880211688359529 105.990754835488 50.5633438008935 2.09619749937533 0.0369886335463012 -215.204797540873 95.4925608943527 -2.25362892695865 0.0250159522622327 ATXN1 other 1 1 1 2.09619749937533 -2.25362892695865 3.63940334636967e-14 608.738843011756 81.6579114237955 7.45474421764804 1.21659222448448e-12 -165.84211246665 153.578035848908 -1.07985566783657 0.281166566027375 NUP153 essential 4.70356488484816e-10 1 1.71101530451497e-08 7.45474421764804 -1.07985566783657 8.08724730722089e-17 1609.23194784355 190.971983777319 8.42653417540018 2.11951102103224e-15 -295.192728668479 358.879114184499 -0.822540841751859 0.411492303679374 DEK other 1.11895153742708e-12 1 3.11695290753001e-11 8.42653417540018 -0.822540841751859 6.26643727060027e-15 136.523081987692 17.5007053310525 7.80100455411083 1.34773971236395e-13 -9.34514795713128 31.5179605719331 -0.296502304957294 0.767074453278073 EEF1E1 other 8.26793733483e-11 1 1.92942417222024e-09 7.80100455411083 -0.296502304957294 0.00156350468982465 105.5823703398 34.6881108825683 3.04376247807884 0.00256690197430074 -64.7361197092671 80.4758957797492 -0.80441626752985 0.421864326852766 RUNX2 other 1 1 1 3.04376247807884 -0.80441626752985 1.37138941606132e-05 219.814232031765 178.950810196811 1.2283500241771 0.22037349873406 -961.005951999192 282.521086115666 -3.40153708599914 0.000770362897929659 LRRFIP1 other 0.111027687124324 1 1 1.2283500241771 -3.40153708599914 0.0148916371960571 26.6046960128688 36.8006133008363 0.722941647612818 0.470334632557857 -120.451439530787 58.2529211270821 -2.06773217892396 0.0396072743627396 RAB17 other 1 1 1 0.722941647612818 -2.06773217892396 0.0139056637168373 -110.28203172626 137.277834144709 -0.803349152566088 0.42248487391698 -776.428587524951 272.90914846772 -2.8450075487916 0.00478377284487188 CXCL6 other 1 1 1 -0.803349152566088 -2.8450075487916 0.764483380725916 1.88869381375088 51.8628768514137 0.0364170660868266 0.970976916721528 -62.8017069188392 103.103706776765 -0.609112018201383 0.542966180787277 EREG other 1 1 1 0.0364170660868266 -0.609112018201383 0.938620155511823 -13.2193108262953 97.744373887309 -0.135243700486906 0.89251996590618 52.3290567575854 197.711442346258 0.264673891083856 0.791462625569039 MYRF other 1 1 1 -0.135243700486906 0.264673891083856 0.24894915987204 43.0665259489878 2381.03390451357 0.0180873215905701 0.985584409819742 -7484.44960457461 4771.38275911982 -1.5686122833615 0.118072451836972 AHNAK other 1 1 1 0.0180873215905701 -1.5686122833615 3.2674518903839e-21 394.926304820533 40.8440765100747 9.66912067954626 3.35590299758977e-19 -135.24500092539 113.551616020507 -1.19104426396684 0.234674522349017 EMC3 essential 4.85020558608586e-17 1 5.11439616832682e-15 9.66912067954626 -1.19104426396684 2.06144085426291e-05 107.622118367004 96.4867062637771 1.1154087701241 0.26566340932908 -386.547636013077 144.040022388515 -2.68361271821003 0.00773133810208693 SH3TC1 other 0.164255607267668 1 1 1.1154087701241 -2.68361271821003 5.51373884022316e-15 777.598048516053 219.021402083108 3.55032905971898 0.000452948887183333 -1633.52899369081 383.432281707908 -4.26028029360136 2.81304999003053e-05 CNOT1 essential 7.2864058773549e-11 0.427921164483444 1 3.55032905971898 -4.26028029360136 1.89905563715326e-08 18.6508499240371 4.74631895276419 3.92953994656745 0.000108183688556083 -14.8711261893962 8.26596990418953 -1.79907819188393 0.073122909426056 LRRC29 other 0.00019020941261727 1 1 3.92953994656745 -1.79907819188393 5.64966825380876e-12 137.109440247925 35.779659254131 3.83204991624101 0.00015776242929002 -189.915277648695 64.1135084432573 -2.96217259451301 0.0033237396742735 BBS2 other 6.75869813203142e-08 1 1 3.83204991624101 -2.96217259451301 0.148820945456961 203.42639699851 117.532201161079 1.73081415126151 0.0846189836276527 61.0575301774969 211.129174074295 0.28919513584613 0.772652351748804 MT1G other 1 1 1 1.73081415126151 0.28919513584613 0.505803737931049 310.622368049972 946.073894503918 0.328327808064981 0.74291550756184 -1200.16999753229 1695.26814641811 -0.70795289822917 0.479578486313497 MT2A other 1 1 1 0.328327808064981 -0.70795289822917 2.19472378278415e-20 127.207037145077 24.3910780565661 5.21531015767598 3.65683336096596e-07 -195.710014956506 42.4783751688021 -4.60728580551366 6.29481268536043e-06 C16orf70 other 3.2231713473968e-16 0.0971982026746504 0.00417610369822313 5.21531015767598 -4.60728580551366 3.86690908562785e-17 627.290709228719 154.705316745664 4.05474564432706 6.5525886290555e-05 -1199.32344750614 271.166154820236 -4.4228360589514 1.40814988868147e-05 GOT2 other 5.39201802899947e-13 0.215967948427077 0.626296421165124 4.05474564432706 -4.4228360589514 0.000174123074463311 84.0323184855325 46.2593927290102 1.81654607914544 0.0703832403540102 -162.89929677099 80.885156654029 -2.01395785715989 0.0449948486804788 DOK4 other 1 1 1 1.81654607914544 -2.01395785715989 0.515813535028508 2.44415702402908 3.38939830496831 0.721118264692095 0.471458387033004 6.88773195371533 6.11493327977528 1.12637892166314 0.261001602722671 GPR18 other 1 1 1 0.721118264692095 1.12637892166314 5.67269469188964e-12 52.8613414748827 8.52456619287622 6.2010594180215 2.08471537868118e-09 -16.5754084180634 15.3794711680997 -1.07776192281854 0.282098428145315 CLYBL other 6.78567739043838e-08 1 2.66155612396227e-05 6.2010594180215 -1.07776192281854 4.8199329634163e-15 289.05606490645 41.8073515981981 6.91400086005229 3.39871419765038e-11 -121.006969600778 75.8336495535298 -1.59568964850308 0.111727881073385 TMTC4 other 6.38351921674855e-11 1 4.6049178663965e-07 6.91400086005229 -1.59568964850308 1.15356940011475e-14 242.771536905147 48.1734976738477 5.03952481401288 8.61398881805813e-07 -333.166196989317 86.6024427142777 -3.84707620879139 0.000149576200470377 RAP2A other 1.51082984333029e-10 1 0.00959770634108037 5.03952481401288 -3.84707620879139 0.00301140858518264 122.946132989572 65.6522078123989 1.87268847592895 0.062237959906487 -175.847979495373 114.07834526969 -1.54146677951591 0.124424093499468 ABCC4 other 1 1 1 1.87268847592895 -1.54146677951591 3.78713701169794e-07 598.203105498903 122.643495317095 4.87757711040647 1.84387819756382e-06 -99.6694315816953 224.763568900563 -0.443441221676765 0.657804396608551 EFNB2 other 0.0034917403247855 1 0.020066926424087 4.87757711040647 -0.443441221676765 0.607501389904555 -79.8112369954795 80.6598089570771 -0.989479618504314 0.323352020741324 -87.3344317954867 140.155797378301 -0.623123933716122 0.53375139080562 SOX21 other 1 1 1 -0.989479618504314 -0.623123933716122 1.11965142959567e-22 1173.75864806452 166.555773591204 7.04724082964186 1.51140865978702e-11 -1343.69750134643 300.489158025084 -4.47170044396166 1.14225216027079e-05 TM9SF2 other 1.68563522725628e-18 0.175598424598428 2.06926959611442e-07 7.04724082964186 -4.47170044396166 1.38286442124024e-11 75.3831826370175 13.9685733201015 5.3966271937405 1.47865473553819e-07 -74.2218348433483 28.8955778101516 -2.56862262215337 0.0107443156787051 C17orf53 other 1.63316288148472e-07 1 0.00173046963700035 5.3966271937405 -2.56862262215337 0.00611678416022072 -135.374802855159 264.053011776067 -0.512680396805947 0.608589464947595 -1278.5024903873 423.072975625913 -3.02194317303255 0.00275000144170447 IRF1 other 1 1 1 -0.512680396805947 -3.02194317303255 2.05037630979674e-15 102.212234967759 19.4457132396502 5.25628624201584 2.99722373915363e-07 -125.026416782582 36.026438888254 -3.47040730754395 0.000605139069271113 ATP5S other 2.74114808856726e-11 1 0.00344262061097548 5.25628624201584 -3.47040730754395 0.340768506741572 -59.3215523051949 74.2707440297702 -0.798720318210585 0.42515461411 -207.030249570248 141.616740192588 -1.461905204771 0.144930088811172 BMP4 other 1 1 1 -0.798720318210585 -1.461905204771 0.214998730665868 -10.3796221476848 6.74384355522489 -1.53912558360625 0.124953471117173 -18.7732495163898 12.8798336969157 -1.45756924803194 0.146130073095734 PTGER2 other 1 1 1 -1.53912558360625 -1.45756924803194 1.12399334726227e-17 142.040581149895 35.6654111103835 3.98258639751225 8.7639186772654e-05 -234.736966517922 56.2600422964081 -4.17235673733059 4.06387205973886e-05 FAM193A other 1.58280743161473e-13 0.615310868565061 0.826262252892582 3.98258639751225 -4.17235673733059 9.10153866776745e-09 13.4123190446806 4.94773073845502 2.71080213408475 0.00713903833974325 -20.9692131386516 7.79928128362773 -2.68860839558002 0.00761795305430452 GRK4 other 9.299042056858e-05 1 1 2.71080213408475 -2.68860839558002 0.658691270350774 -71.2737373893224 122.738061582388 -0.58069792263649 0.561928426447085 -214.447261144406 257.567640343039 -0.832586193121141 0.405813977943972 SOX9 other 1 1 1 -0.58069792263649 -0.832586193121141 0.342372286921159 24.1519682280113 23.8536539103846 1.01250602187604 0.31219598669821 -35.8674854406181 64.5444465935731 -0.555702114334799 0.578871294855817 HS3ST3B1 other 1 1 1 1.01250602187604 -0.555702114334799 6.6293892831252e-13 128.94192424124 16.9500616663916 7.60716549467806 4.55052587785556e-13 11.1815570275886 50.4657109374436 0.221567413197627 0.824816294172609 SLC25A35 other 8.22839797821499e-09 1 6.46265685173046e-09 7.60716549467806 0.221567413197627 2.73808716498794e-21 674.794754749279 65.4354754848106 10.312368783901 2.91399403165539e-21 -13.3973950584394 148.948416656212 -0.0899465422943157 0.92839589236407 MRPS7 essential 4.06797610102258e-17 1 4.48755080874931e-17 10.312368783901 -0.0899465422943157 1.99924512417807e-07 173.67813716498 31.1169778342571 5.5814590378946 5.76596078607079e-08 9.83307593580694 70.8304561890884 0.138825534450274 0.889690742324456 GGA3 other 0.0018782907941653 1 0.000690531463739837 5.5814590378946 0.138825534450274 8.3569545959743e-11 91.5717906864097 14.548201240033 6.29437201036422 1.2312143670237e-09 -54.6113518771855 32.8147434281211 -1.66423217651568 0.0972175816382034 ARMC7 essential 9.54197075768346e-07 1 1.58666595478344e-05 6.29437201036422 -1.66423217651568 3.15852917998853e-13 272.459956027502 35.3148156759457 7.71517423530219 2.299073066914e-13 -14.1994619514185 79.6556630264841 -0.178260545602356 0.858651055186234 NUP85 essential 3.95921632711563e-09 1 3.28238661763311e-09 7.71517423530219 -0.178260545602356 7.06969277161081e-11 96.0668329729767 14.2726439467586 6.73083651013338 9.96654625435582e-11 -23.0308087155197 32.4883054889857 -0.708895350769456 0.478996558511284 SLC25A19 other 8.09762610060302e-07 1 1.33192924143211e-06 6.73083651013338 -0.708895350769456 2.63449633837071e-11 157.878598358472 24.6449922461103 6.40611272188124 6.54092586056557e-10 -105.266224100111 56.0985084369847 -1.87645317198328 0.061663707757412 MIF4GD other 3.07208618017409e-07 1 8.50516589649341e-06 6.40611272188124 -1.87645317198328 3.09150233322519e-06 135.738524294524 28.5685507665806 4.75132691901581 3.27632860670933e-06 -49.9061668336188 64.4388710364354 -0.774473016533771 0.439323802678573 NT5C other 0.0264137959350761 1 0.0349518735763751 4.75132691901581 -0.774473016533771 3.76896154324321e-05 199.371606107888 43.3546594504937 4.59862004764559 6.56249339954865e-06 60.9422932641637 143.209757169395 0.425545678372169 0.670780449228028 MSTO1 essential 0.292320657293943 1 0.0684336811704933 4.59862004764559 0.425545678372169 0.00538942010020118 55.8475005569952 17.1279905429004 3.26059851662776 0.00125341720665304 20.1600120389154 57.087299254659 0.353143559112583 0.724254346177637 C1orf61 other 1 1 1 3.26059851662776 0.353143559112583 5.9046290915694e-24 118.621170024759 13.5952747587896 8.72517636674228 2.67523446314807e-16 -98.2579019232515 26.5297933359655 -3.70368139242332 0.000257134568381104 TTF1 other 8.98212177409537e-20 1 3.97914374048644e-12 8.72517636674228 -3.70368139242332 1.6406514485329e-21 426.376788329998 51.9471929051695 8.20788890572694 8.9944289654643e-15 -344.68559959556 101.369653545743 -3.40028388713021 0.000773757062013696 GTF3C4 essential 2.44128935541695e-17 1 1.31111791029573e-10 8.20788890572694 -3.40028388713021 5.90326670930505e-24 131.987030691653 13.8245674317393 9.54728105189239 7.96082390843853e-19 -64.3053858385436 26.9772346223487 -2.38369079480338 0.0178237776021083 DDX31 other 8.98063964486578e-20 1 1.21012484232174e-14 9.54728105189239 -2.38369079480338 6.30347907470112e-09 115.058171385182 54.0916596744423 2.12709634124142 0.0343153190507363 -546.771860452376 120.266246980844 -4.54634508167089 8.23526833758954e-06 PPP1R12C other 6.5020386655542e-05 0.12692195561893 1 2.12709634124142 -4.54634508167089 8.47723194943656e-08 402.139218741246 98.3863196646156 4.08734893338911 5.74272261958832e-05 -617.972860880673 251.515370803407 -2.45699838903167 0.01463274033608 MBOAT7 other 0.000815340168896809 1 0.552162779873417 4.08734893338911 -2.45699838903167 0.176068406954313 1.01834714522491 2.19232353691245 0.464505866984897 0.642658313279282 -9.96382846583221 6.13839869987561 -1.62319669232859 0.105709996172768 SRMS other 1 1 1 0.464505866984897 -1.62319669232859 0.034430712803695 9.19453176053078 3.84798221630331 2.38944237360946 0.0175682634485965 -4.42812561114638 10.8336844001964 -0.408736810818128 0.683060455760861 OPRL1 other 1 1 1 2.38944237360946 -0.408736810818128 4.21378162370721e-06 380.158560655596 81.6152731422769 4.65793406085745 5.0102762675103e-06 -172.516419191969 228.543716112844 -0.754850853596817 0.450993962785235 SLC2A4RG other 0.0356401649733156 1 0.0526880652291383 4.65793406085745 -0.754850853596817 0.00502614687737041 6.6770474938561 2.62959124874383 2.53919596707121 0.011670243360454 -9.84661751538359 7.3627269108401 -1.33736014314024 0.182226476189796 FNDC11 other 1 1 1 2.53919596707121 -1.33736014314024 7.44268889817616e-06 910.841638248814 209.601953853533 4.34557799439835 1.96386304305328e-05 -683.692281731716 586.90107847215 -1.16491910955682 0.245072366040988 PPDPF other 0.0615956933213059 1 0.196779076913939 4.34557799439835 -1.16491910955682 0.755976744955241 -10.03152639087 84.3979614734416 -0.118859818599134 0.905474473860316 -195.534910445395 263.010369689161 -0.743449433862583 0.457853667997794 IL1B other 1 1 1 -0.118859818599134 -0.743449433862583 0.232547846066595 1.02080461210678 2.18233677820553 0.467757599240092 0.640340940517427 -13.6681516252891 8.79728079974221 -1.55367913522661 0.121449921654867 PLGLB2 other 1 1 1 0.467757599240092 -1.55367913522661 1.53065934251686e-05 65.5607047402536 18.0309359872697 3.6360122839181 0.000330888070328309 -120.858591133913 57.1602660226538 -2.11438118720466 0.0353892610510207 CHCHD5 other 0.12346298256741 1 1 3.6360122839181 -2.11438118720466 0.00862022151535588 33.9421125348635 12.8252009813582 2.64651700852091 0.00861002587604518 -33.3026474905285 39.1485246779614 -0.850674393594101 0.395704012529571 PAX8 other 1 1 1 2.64651700852091 -0.850674393594101 0.00108883264013366 87.3367836039832 23.9714415922445 3.64336801639162 0.000322412301329269 20.6255733234165 74.3158019742256 0.277539537695764 0.781577454580784 INSIG2 other 1 1 1 3.64336801639162 0.277539537695764 3.28277786982918e-08 211.628352431568 36.0763474092311 5.86612469469173 1.28722182025677e-08 2.17301260585942 114.366420938616 0.0190004425077335 0.98485463145108 POLR1B essential 0.000324108659088235 1 0.000159087744765535 5.86612469469173 0.0190004425077335 7.69273579128316e-08 134.0700656622 30.8525178772459 4.34551456045273 1.96679720494576e-05 -240.374959148947 95.6483822697365 -2.51311055602664 0.0125478427636152 CCDC93 other 0.000742015818544446 1 0.197053411963516 4.34551456045273 -2.51311055602664 0.00713976413064466 24.1507078348065 58.5769229575032 0.412290482590345 0.680453680328622 -531.960628681658 182.454840659783 -2.91557421418918 0.00384826930688534 PSD4 other 1 1 1 0.412290482590345 -2.91557421418918 9.25395874007866e-08 147.491638854568 70.5527367967206 2.09051619470875 0.0374997667310502 -470.010571516729 130.908718178941 -3.59036875507608 0.000391660450502461 SLC25A23 other 0.000887917341110547 1 1 2.09051619470875 -3.59036875507608 4.65386786145475e-19 17.1745566794173 2.94574575108903 5.83029159019171 1.56419410198472e-08 -21.0338696790415 5.46575254007794 -3.84830259416419 0.000148276596642308 PSPN other 6.71273900336234e-15 1 0.00019244280036718 5.83029159019171 -3.84830259416419 1.00452034731343e-25 437.462901332959 66.3507532494047 6.59318666192963 2.22988852272943e-10 -627.748743234486 123.112049970689 -5.09900325259746 6.40657634666795e-07 GTF2F1 other 1.54595681451536e-21 0.01005576223373 2.94724366049149e-06 6.59318666192963 -5.09900325259746 5.15568348834519e-05 103.898285193813 41.472166128402 2.50525339988593 0.0128212816095409 -147.249505175948 76.9504962453213 -1.91356147602363 0.0567257982569483 ALKBH7 other 0.394461343693291 1 1 2.50525339988593 -1.91356147602363 3.9634524886842e-23 220.800676056338 34.6507424996237 6.37217733671178 7.97143984681378e-10 -293.524717122009 64.2595704691391 -4.56779768335015 7.49038578452884e-06 CLPP other 5.9903620913973e-19 0.115554181497926 1.03341746174094e-05 6.37217733671178 -4.56779768335015 4.5214522303377e-07 53.1137246474251 12.2371102763687 4.34038130309195 2.0077934175766e-05 -15.8685789084364 22.7056311806778 -0.698882967937064 0.485222318265484 TNFSF9 other 0.00414436311432753 1 0.200980121099418 4.34038130309195 -0.698882967937064 4.65660796339298e-14 329.416558000089 49.8561019515911 6.60734684632873 2.14910472517753e-10 -137.783761869733 96.6585973959135 -1.42546825198974 0.155203135869114 MED1 essential 5.99957370003552e-10 1 2.84262081999232e-06 6.60734684632873 -1.42546825198974 4.81353897385207e-15 3123.58437753671 482.580290251865 6.4726729222747 4.66398532960017e-10 -1718.06053722972 923.481104431624 -1.86041764036649 0.0639383407395564 RPL23 essential 6.37553237086707e-11 1 6.0948960287215e-06 6.4726729222747 -1.86041764036649 4.20706721419012e-31 63.5961534932374 5.3918019736555 11.7949720342049 3.17323163780607e-26 -38.5666437201473 16.711176364966 -2.30783535987329 0.0217561887065836 ATG4C other 6.60467481955706e-27 1 4.97086736062321e-22 11.7949720342049 -2.30783535987329 0.000524107397021297 115.189823803563 30.053813746442 3.83278557508196 0.000157436420131753 67.5068258098069 55.7640484630814 1.21057971346 0.227107396055495 CD70 other 1 1 1 3.83278557508196 1.21057971346 0.389227768464595 -2239.73107784526 1638.06720224778 -1.36730109410155 0.172655636960994 -1777.44484705286 3059.32687626512 -0.580992132891269 0.561725083937773 C3 other 1 1 1 -1.36730109410155 -0.580992132891269 0.0462339255793171 60.2349629723601 40.4859816529931 1.48779801089267 0.137958296318506 -70.3384024991677 75.6134129375255 -0.930237106970476 0.353070168752152 SH2D3A other 1 1 1 1.48779801089267 -0.930237106970476 0.291360561069482 78.8930321434802 78.100736767906 1.01014453138808 0.313320508921808 -73.2768985585386 145.864395991991 -0.502363157645147 0.615817056182303 TRIP10 other 1 1 1 1.01014453138808 -0.502363157645147 0.155365428883092 -11.4992864052267 8.16175730125848 -1.4089228557989 0.159995942995799 6.06021947003694 15.2432595164775 0.397567164915484 0.691259945488921 TNFSF14 other 1 1 1 -1.4089228557989 0.397567164915484 0.617603362926695 45.2550587701119 532.763441464093 0.0849440018739762 0.93236816914191 1413.19404194661 1496.78412469431 0.944153548017639 0.345926015783518 FOSB other 1 1 1 0.0849440018739762 0.944153548017639 7.700795903282e-25 173.74076362203 18.8595866448949 9.2123314732913 8.7942537259666e-18 -174.231034506606 52.336560592168 -3.32905014267749 0.000991314029643904 OPA3 other 1.17783673340698e-20 1 1.32590963426398e-13 9.2123314732913 -3.32905014267749 6.53243658967973e-17 1330.55811996745 163.424129753269 8.14174823495328 1.39745883182954e-14 -500.490121046286 453.512424747098 -1.10358634898567 0.270744426176343 SNRPD2 essential 9.06048954988579e-13 1 2.03190514148015e-10 8.14174823495328 -1.10358634898567 0.470740943109171 13.1980075729525 10.7378317793336 1.22911290139168 0.220087833193971 12.7921094421753 30.1676408140474 0.424034133826556 0.6718748477698 RTN2 other 1 1 1 1.22911290139168 0.424034133826556 3.66244415138665e-07 289.913125955171 83.3126795351042 3.47981996945633 0.000583881434237687 -654.331008871131 231.720549858896 -2.82379361377133 0.00509549088293324 VASP other 0.00338153468497529 1 1 3.47981996945633 -2.82379361377133 2.10130263537056e-25 599.060000398146 69.2757622086163 8.64746891696613 4.63496247159631e-16 -796.506466267192 185.19144563111 -4.30098951683645 2.37276130873991e-05 SYMPK essential 3.22591980582089e-21 0.36163255106505 6.87503983411881e-12 8.64746891696613 -4.30098951683645 0.000405447079648948 246.28976543034 75.0883989224155 3.27999756240398 0.00117340693530937 -401.411043051045 274.403473537232 -1.46284971497119 0.144663031442316 GPCPD1 other 1 1 1 3.27999756240398 -1.46284971497119 0.477531542823963 -2.37399101718137 42.4267056158074 -0.0559551108841424 0.955418798682526 -205.140840139099 169.454466302698 -1.21059565212435 0.22710516836364 SDCBP2 other 1 1 1 -0.0559551108841424 -1.21059565212435 1.0284600403533e-23 223.407444473919 20.6840304783624 10.8009628349575 7.48697025683469e-23 -80.1884689496583 74.7811480035412 -1.0723086110668 0.284535408984056 PANK2 other 1.56171657127648e-19 1 1.16100447772736e-18 10.8009628349575 -1.0723086110668 0.219513634926047 53.3886859982103 58.5578243860313 0.911725914649006 0.362717383908834 -318.454025683195 239.387668029293 -1.3302858426451 0.184534309955405 TGM3 other 1 1 1 0.911725914649006 -1.3302858426451 0.322897357964258 23.4175956283594 25.1578472427793 0.930826688085586 0.352780939998405 -72.2329299292349 83.7072921241948 -0.862922788400136 0.388951469058185 FOXA2 other 1 1 1 0.930826688085586 -0.862922788400136 0.846466554166223 -4.09805262581966 208.613476487685 -0.0196442372507108 0.984341901339026 -373.079494280351 671.30474106049 -0.555752807124497 0.578846981802196 CD93 other 1 1 1 -0.0196442372507108 -0.555752807124497 4.16460862311214e-28 128.915486612843 11.9736947342387 10.7665586499555 1.09300954968733e-22 -122.883697469506 39.2737222758421 -3.12890376436496 0.00194907218794692 GZF1 other 6.47554994807706e-24 1 1.69318109342065e-18 10.7665586499555 -3.12890376436496 0.534351969157153 -0.862439321847307 5.77402490140902 -0.149365362389907 0.881377679854059 -21.2537327710878 19.2118182645116 -1.10628429222382 0.269595536912333 PAX1 other 1 1 1 -0.149365362389907 -1.10628429222382 0.000367262411703336 78.1227973888733 23.4904293702867 3.32572879607266 0.00100507451688041 -89.7908108899944 77.0483696102948 -1.16538236103048 0.244900427595619 NAPB other 1 1 1 3.32572879607266 -1.16538236103048 1.18692130200807e-13 490.388923722479 74.7882069056638 6.5570354473272 2.76478683100156e-10 -881.810811473096 270.389660051144 -3.26125936659819 0.00125115060430448 CENPB other 1.50988258828446e-09 1 3.64067129906285e-06 6.5570354473272 -3.26125936659819 1.91731387396966e-32 796.669826840815 60.3561176448165 13.1994876066922 4.9450434523997e-31 -513.101940484661 232.115503872004 -2.21054574953168 0.027905860033952 PSMF1 other 3.01823550040303e-28 1 7.81069613306532e-27 13.1994876066922 -2.21054574953168 5.3745006510441e-09 191.427224513847 36.4504658542611 5.25170858663989 3.05802047754768e-07 -259.238259237435 123.152359570409 -2.10502064387343 0.0362134783260756 DTD1 other 5.56583287422127e-05 1 0.00351091331027249 5.25170858663989 -2.10502064387343 1.97355269035414e-18 551.059381622878 60.2855119730474 9.1408261054372 1.70568248708253e-17 -421.821851536957 228.64666610531 -1.8448633374898 0.066177468176451 RBCK1 other 2.81882530763282e-14 1 2.56568759706955e-13 9.1408261054372 -1.8448633374898 0.412981811381518 83.1008423719578 83.9989061372956 0.989308625473408 0.323401195297515 -190.646673455241 305.921593912134 -0.623188023497282 0.533688972529139 TMX4 other 1 1 1 0.989308625473408 -0.623188023497282 1.51389856320478e-27 603.308630482726 50.0357162604692 12.0575595908751 3.99182881149445e-27 -278.733365672724 201.139970579609 -1.38576815373653 0.166948686157973 STK35 other 2.3486622309559e-23 1 6.26717123404629e-23 12.0575595908751 -1.38576815373653 2.43554393895254e-13 1190.49739604343 167.639896366836 7.10151593889286 1.07088831427492e-11 -1334.03176256086 622.616348426691 -2.14262244467539 0.0330277699432113 SNRPB essential 3.06756759111072e-09 1 1.47204307680231e-07 7.10151593889286 -2.14262244467539 3.03582695792394e-16 312.015137175207 36.3347734723949 8.58723221192665 7.83857650697194e-16 -189.33541422143 137.807983149733 -1.37390744639017 0.170635812413257 NRSN2 other 4.14360021487038e-12 1 1.15807129314003e-11 8.58723221192665 -1.37390744639017 7.5166071325111e-22 100.09866882099 10.4491569836641 9.57959278221978 6.55331320630218e-19 -103.891202643066 37.7779348045849 -2.75004981559916 0.00635969381464308 AP5S1 other 1.12305627166848e-17 1 9.96890004942688e-15 9.57959278221978 -2.75004981559916 1.78188667014275e-06 825.911474619906 242.149719756131 3.4107471834024 0.000746978245933833 -2445.54469162237 826.891667627691 -2.95751521918041 0.00337584037127353 RRBP1 other 0.0155629981770268 1 1 3.4107471834024 -2.95751521918041 0.0416742082129086 88.775895578083 45.3661261158981 1.95687626823777 0.0513848885631696 -178.79715919692 163.259216541795 -1.09517344860679 0.274409449125687 BMP2 other 1 1 1 1.95687626823777 -1.09517344860679 1.01719229145998e-09 91.1875317074605 15.4783355795651 5.8913008597545 1.13721109386571e-08 -75.3542147946091 52.0737736574527 -1.44706652700643 0.149038291355409 ZNF133 other 1.09805907863105e-05 1 0.000140877710308084 5.8913008597545 -1.44706652700643 0.0241314575193038 139.55291352356 58.8763891842528 2.37026956742933 0.0184859487875549 -144.370565485951 206.79153091977 -0.698145445530666 0.485693810777594 FLRT3 other 1 1 1 2.37026956742933 -0.698145445530666 3.2416892852816e-05 33.1871384821341 9.01608655592869 3.68088064331096 0.000280616701275933 -53.0659940846655 30.7880878624007 -1.7235884970132 0.085926908637828 OVOL2 other 0.253111099394787 1 1 3.68088064331096 -1.7235884970132 0.227220114452723 49.3717047369845 33.4393625671483 1.47645472122392 0.140982895465294 -53.6615724143068 115.017494569439 -0.466551393900431 0.641195697321608 PCSK2 other 1 1 1 1.47645472122392 -0.466551393900431 1.85023993418292e-09 192.332949414908 36.9098312705502 5.21088671484574 3.82086932208865e-07 -300.974000717519 131.822326954931 -2.28317924337976 0.0232240278320921 MKKS other 1.9714306498719e-05 1 0.0043573193749099 5.21088671484574 -2.28317924337976 0.000344581821113643 23.8717931229357 6.59767262759731 3.61821425074695 0.000353804907898034 -17.2411778604904 22.2069255222003 -0.776387431175666 0.438197345609531 BFSP1 other 1 1 1 3.61821425074695 -0.776387431175666 1.18271282164412e-05 1097.97650807261 272.13773192044 4.03463533088315 7.11836448735754e-05 -1394.63400629439 915.980935346671 -1.5225578966516 0.129035348864637 DSTN other 0.0962609965536147 1 0.67852250293492 4.03463533088315 -1.5225578966516 0.149107490102522 44.5015918158645 23.1911955321126 1.91890028930348 0.056075113435242 8.280562677983 85.4133871168918 0.0969468950651811 0.922842124282919 LAMP5 other 1 1 1 1.91890028930348 0.0969468950651811 1.93422534696038e-14 205.84492057036 27.6428947414912 7.44657614534823 1.30274250909411e-12 -200.404102691456 98.391635659273 -2.03680019494186 0.0426491443139808 SNRPB2 other 2.51584690879137e-10 1 1.83087432228086e-08 7.44657614534823 -2.03680019494186 1.83002348327911e-15 227.010278731555 30.5586756895375 7.42866873675672 1.44540041184711e-12 -255.89676124374 102.808570918269 -2.48906058082623 0.0134107677821707 MGME1 other 2.44857142062746e-11 1 2.02876401806861e-08 7.42866873675672 -2.48906058082623 0.550136076851894 -2.18767413202372 16.3167505250489 -0.13407535579252 0.893442136562383 -64.8163240709499 59.6280262353188 -1.08701106112679 0.277994242567795 LRRN4 other 1 1 1 -0.13407535579252 -1.08701106112679 5.72752708748429e-29 336.383614457832 26.6568076064523 12.6190509915527 6.95889123798878e-29 -77.7568100975329 101.102072268225 -0.769092149676646 0.442526124059004 TBC1D20 other 8.936087761893e-25 1 1.09567742542133e-24 12.6190509915527 -0.769092149676646 8.85232366371951e-12 197.325549133284 30.2691092398445 6.51904050329753 3.40678936118272e-10 -251.234380152324 109.033557630129 -2.30419318247488 0.0219627711689531 ITPA other 1.05209866743306e-07 1 4.47243307336067e-06 6.51904050329753 -2.30419318247488 0.00718222377458378 7.45993730379911 2.88037226013078 2.58992124283977 0.0101308364571674 -14.8495522407781 10.9223892119782 -1.35955164685883 0.175127545144304 TCF15 other 1 1 1 2.58992124283977 -1.35955164685883 3.56301697025461e-17 246.597724488452 28.5209701012105 8.64618993019406 4.67586937688385e-16 -145.536385631728 104.227195901595 -1.39633791711268 0.163751217467433 MCM8 other 4.97254648368733e-13 1 6.93478187285643e-12 8.64618993019406 -1.39633791711268 0.0109221578850772 24.6806602204943 8.2126235330893 3.00521022558188 0.00290349825015263 2.11030279048815 31.8912697964661 0.066171801999618 0.947290016662246 TMEM74B other 1 1 1 3.00521022558188 0.066171801999618 1.79269548470322e-11 196.319096953261 27.3101252132994 7.18850958829213 6.52176458294322e-12 -39.7035169280567 103.548683144692 -0.38342850649851 0.701706051091622 FAM110A other 2.10659646407475e-07 1 9.00981777133606e-08 7.18850958829213 -0.38342850649851 2.72587891100839e-14 292.045968414582 39.4064762468419 7.41111604562682 1.58694243139107e-12 -318.779794886657 140.255608966624 -2.27284881678076 0.0238155455418287 MRPS26 essential 3.53437459601348e-10 1 2.22584545426911e-08 7.41111604562682 -2.27284881678076 0.23798380578925 -22.1549716333234 13.2703039648851 -1.66951500824308 0.0961700434904842 -27.0562108091968 22.2723110994739 -1.21479134735308 0.225503069201653 S1PR4 other 1 1 1 -1.66951500824308 -1.21479134735308 5.30036452596182e-12 266.072111077933 104.404468896392 2.54847435067148 0.0113715474284229 -766.91472691984 175.227999116591 -4.37666771740947 1.72182118388234e-05 NCLN other 6.34612644693409e-08 0.263490295769514 1 2.54847435067148 -4.37666771740947 1.08062531807645e-09 799.202547104658 167.745823919003 4.76436628008431 3.08675635917036e-06 -244.437346609908 248.072688866012 -0.985345657062363 0.325329983171581 HNRNPR other 1.16523828048184e-05 1 0.0330221195304045 4.76436628008431 -0.985345657062363 1.91840932252855e-10 154.416471901082 59.1469520735767 2.61072576840466 0.00953614821736883 -323.462735718381 87.4700966994333 -3.69798077198737 0.000262870545094552 ZNF436 other 2.15303078267379e-06 1 1 2.61072576840466 -3.69798077198737 5.28272220726373e-17 219.671136315984 38.171700514863 5.75481661422052 2.32591091636859e-08 -241.206035898639 70.7605784766299 -3.40876291702876 0.000751062023587159 MAX other 7.33822941811005e-13 1 0.000283551799814494 5.75481661422052 -3.40876291702876 1.37207638217848e-28 203.674571902589 22.2057704466326 9.17214614967237 1.16980674751325e-17 -131.324813355454 41.2376576376948 -3.18458469463144 0.0016176243338428 CHURC1-FNTB other 2.13673454996655e-24 1 1.76219688445396e-13 9.17214614967237 -3.18458469463144 0.456796467803133 1.26742379459436 2.74927573572049 0.461002793618377 0.64517330318617 -12.6825672300507 12.153733960652 -1.04351199977808 0.297658645252564 GDF5 other 1 1 1 0.461002793618377 -1.04351199977808 0.000248147423757439 68.4142009021766 20.029685753295 3.41564025241495 0.00073616646230557 -139.211748864877 88.4175197360314 -1.57448149733775 0.116569250534557 MMP24 other 1 1 1 3.41564025241495 -1.57448149733775 2.5029234503315e-11 122.879594563602 18.9215140243868 6.49417347920626 4.0359735959261e-10 -178.260773199256 94.9915901109776 -1.87659531744859 0.0616601219650226 NECAB3 other 2.92241342060705e-07 1 5.28873980010156e-06 6.49417347920626 -1.87659531744859 0.328074387664636 142.282667596954 145.68654263728 0.976635624823627 0.329682474496933 -611.806857956862 659.675002880016 -0.927436776118285 0.354583708405133 ID1 other 1 1 1 0.976635624823627 -0.927436776118285 3.36410460006739e-28 1151.68735118213 97.5436382041462 11.8068935338643 3.50073093330791e-26 -887.070001559931 449.928724491916 -1.97157894855826 0.0496861532600225 RALY other 5.23252829494481e-24 1 5.48354493393351e-22 11.8068935338643 -1.97157894855826 1.43280453847801e-17 430.90663899122 52.3896504049156 8.22503367861355 8.833570141336e-15 -656.416656604519 231.787856554931 -2.83197172777235 0.00498123019292426 DYNLRB1 essential 2.01452318110008e-13 1 1.28775785520396e-10 8.22503367861355 -2.83197172777235 3.15957747900995e-26 445.590753011256 39.8432464705946 11.1835955270391 4.39968294006218e-24 -388.014092763567 183.780525251821 -2.11129058550627 0.03567328567453 EIF2S2 essential 4.87175251488545e-22 1 6.85558595720489e-20 11.1835955270391 -2.11129058550627 6.57341621838853e-29 1646.23981087412 139.581327191628 11.7941263634357 4.18252595447592e-26 -1682.39024634399 616.068649848466 -2.73084865908663 0.00673945051588656 ERGIC3 other 1.02512425925769e-24 1 6.55067214990018e-22 11.7941263634357 -2.73084865908663 5.61932446781114e-17 530.593396770471 59.9959564707173 8.84381928354525 1.28804239952534e-16 -215.098458214077 258.212299111951 -0.833029483699451 0.405572637387855 ROMO1 essential 7.80243202355576e-13 1 1.92137284737195e-12 8.84381928354525 -0.833029483699451 0.783567145887997 8.77791103256808 39.2122388753743 0.223856410251563 0.8230408685785 -104.077290185604 173.34569723249 -0.60040307805285 0.54874882097512 FAM83C other 1 1 1 0.223856410251563 -0.60040307805285 0.0294481164116718 -505.588142822482 245.630079772006 -2.0583315499949 0.040525087152331 -2638.11777428122 1259.47041265195 -2.09462465158382 0.0371433830180705 BPIFB1 other 1 1 1 -2.0583315499949 -2.09462465158382 6.00949447065788e-21 583.815597996532 57.4681330535913 10.1589449139074 1.05826811634623e-20 -176.828058173359 253.646500230165 -0.697143694129036 0.486321703946176 CEP250 other 8.89044611989127e-17 1 1.62571148033107e-16 10.1589449139074 -0.697143694129036 4.22863678078465e-08 320.468456631631 53.2530052115683 6.01784735637821 6.08857548380666e-09 206.235695659152 257.594459863003 0.800621627378302 0.424093106862805 PLAGL2 other 0.000414660122723743 1 7.62898508120974e-05 6.01784735637821 0.800621627378302 4.72025977173695e-06 194.053193114688 43.8064409083135 4.42978678685262 1.37005168984841e-05 -88.93163431598 103.684017581468 -0.857717866170679 0.391806180593772 TMEM115 other 0.0397445872780251 1 0.139101348070309 4.42978678685262 -0.857717866170679 8.56782510312308e-17 511.657259692396 137.349346340574 3.72522529829652 0.000237443521221154 -1033.56517379244 196.647119680866 -5.25593853329655 2.98759004774939e-07 PSMB2 essential 1.18484453351089e-12 0.00470455804819096 1 3.72522529829652 -5.25593853329655 3.24334824275418e-13 138.72857799083 31.8462341635412 4.3562003996583 1.8792296576722e-05 -157.62410067045 45.5951949375443 -3.45703315637451 0.000633939970049727 AGO3 other 4.06521268746808e-09 1 0.188731034520019 4.3562003996583 -3.45703315637451 6.72017056703079e-19 168.798302184263 47.5450236376728 3.55028327403153 0.00045355425913972 -500.736405458151 82.26718715487 -6.08670872039787 3.92260462939626e-09 UROD essential 9.67234149712741e-15 6.23968718398062e-05 1 3.55028327403153 -6.08670872039787 0.0144808243558144 73.565328824301 31.1000851616918 2.36543817940784 0.0187131308897777 -26.6859692977493 59.4238444957502 -0.449078472189019 0.653733961810773 ST3GAL3 other 1 1 1 2.36543817940784 -0.449078472189019 3.79365485549859e-22 92.5396431634481 17.2175608867083 5.37472431620016 1.65501254038353e-07 -161.073403158597 30.0162292501885 -5.36621045288645 1.72714989563241e-07 TMEM53 other 5.68555053193574e-18 0.00272475167534969 0.00193239264215181 5.37472431620016 -5.36621045288645 7.74015339922794e-15 100.35947531182 43.9402499431529 2.28399873559343 0.0231453025031966 -448.354729667277 76.02984474785 -5.89708858612335 1.09835316547143e-08 HECTD3 other 1.01837198273642e-10 0.000174495367398446 1 2.28399873559343 -5.89708858612335 1.03206696228629e-21 715.292192881521 78.2130874983013 9.14542841563513 1.56650033474893e-17 -207.767765134027 183.826022745429 -1.13024131203531 0.259388842955989 KLC1 other 1.54015352781984e-17 1 2.35711305369671e-13 9.14542841563513 -1.13024131203531 7.22688524460379e-26 350.704142720401 32.3572908754802 10.8384890462557 6.33625334473132e-23 3.89390490025742 76.0500867400955 0.0512018469297085 0.959202964161241 XRCC3 essential 1.11272352111165e-21 1 9.83133068968512e-19 10.8384890462557 0.0512018469297085 7.01187183239542e-27 286.784868727965 29.2288263797785 9.81171344349194 1.35048747718991e-19 -143.761321024457 55.3490821283328 -2.5973569117394 0.00991753851145752 TUBGCP3 essential 1.0848066911899e-22 1 2.06354486514619e-15 9.81171344349194 -2.5973569117394 6.95692843441557e-05 121.008706829746 57.325940988819 2.11088914970184 0.0357150848730592 -286.718264593046 108.861687166834 -2.63378487009522 0.00893845579593226 MCF2L other 0.524969819660999 1 1 2.11088914970184 -2.63378487009522 0.708892069232417 5.83152332544916 7.02660132244595 0.829920904551791 0.407333332806566 4.37980689734502 13.1600988208391 0.332809575138568 0.739542158947044 F10 other 1 1 1 0.829920904551791 0.332809575138568 5.46807236645062e-26 371.816566856223 35.9902043379267 10.3310490644923 3.11294311431594e-21 -93.8184576230977 67.4059369436993 -1.39184264587049 0.165141545395816 PCID2 essential 8.42356548051719e-22 1 4.79268721880082e-17 10.3310490644923 -1.39184264587049 3.67884164245769e-07 61.7995770907781 14.1113502126062 4.37942338328265 1.70814420739901e-05 -131.188218238542 55.8659686553627 -2.34826713643582 0.0195880896217509 LRFN3 other 0.0033952029518242 1 0.17201012168508 4.37942338328265 -2.34826713643582 0.0010117508316226 23.7076472526861 9.0570090179237 2.61760225762931 0.0093564282775297 -72.0664331336337 36.2355359239792 -1.98883309701356 0.0477326228814349 IGFLR1 other 1 1 1 2.61760225762931 -1.98883309701356 9.59463241854316e-14 1414.6466296039 198.945392211388 7.1107282952338 1.02686306907649e-11 -1821.93126686814 805.397350392054 -2.26215204952097 0.0244802023862502 CAPNS1 other 1.22360347233681e-09 1 1.41245015151471e-07 7.1107282952338 -2.26215204952097 1.50310251815401e-25 109.795640675974 9.612433656012 11.4222521169031 7.23385414982703e-25 -25.5883038115831 35.2363436990215 -0.726190663541907 0.468357998534581 PDCD2L other 2.31026857040271e-21 1 1.13028971091047e-20 11.4222521169031 -0.726190663541907 2.83815337048198e-27 525.767117261914 46.3976722635472 11.3317563492294 1.31264126373157e-24 -414.456003921863 181.236762191633 -2.28682083540885 0.0229804565784328 RBM42 essential 4.39771864756183e-23 1 2.04798289967399e-20 11.3317563492294 -2.28682083540885 0.616688607319139 -1.74002023696837 7.10490643065601 -0.244904032720345 0.806718152783645 24.6636116926779 28.3839606180806 0.868927773137028 0.385664129511484 KIRREL2 other 1 1 1 -0.244904032720345 0.868927773137028 4.85721327869004e-32 1485.60055351712 110.001838265025 13.5052338847092 4.96148231302348e-32 109.453083396746 403.234260889422 0.271437955582751 0.786263961473824 UBA2 essential 7.63796788074008e-28 1 7.84261509219621e-28 13.5052338847092 0.271437955582751 0.927299317531399 1.13617079573021 5.98481160083241 0.1898423662279 0.849575299836484 -7.00354794412298 24.406882581699 -0.286949712675491 0.774370910329088 FFAR2 other 1 1 1 0.1898423662279 -0.286949712675491 0.979345950246727 -0.625708946660989 8.95504431757914 -0.0698722333995261 0.944347461188048 -7.19989532100921 35.4524703600893 -0.203085856863575 0.839222029222288 HCST other 1 1 1 -0.0698722333995261 -0.203085856863575 6.96046066809389e-24 1371.41703066885 126.184471741888 10.8683502156596 4.6146415802362e-23 -397.718808387525 494.711451273252 -0.803940978855262 0.422138303783443 COX6B1 other 1.05833804458368e-19 1 7.16792276658088e-19 10.8683502156596 -0.803940978855262 0.549275189058112 6.02021455808173 9.81996374069833 0.613058735963684 0.540347889775419 20.6731453277354 19.0444043279812 1.08552333649844 0.278647549340159 KRT36 other 1 1 1 0.613058735963684 1.08552333649844 1.81413815971694e-11 149.850775365059 22.9155728509068 6.53925504459425 3.13133663492953e-10 -170.649413788732 101.579322800029 -1.67996211320168 0.0941342999281224 THRA other 2.13124951003546e-07 1 4.11676827394185e-06 6.53925504459425 -1.67996211320168 0.552881696461456 -20.17889074261 32.823306515349 -0.614773247575587 0.539231984310726 41.7584757819824 72.6039859058414 0.575154039561108 0.565675129783316 CCR7 other 1 1 1 -0.614773247575587 0.575154039561108 0.379484490428642 15.86005879489 27.1374478735754 0.584434426876725 0.559421553547472 -130.196788622044 120.293897754766 -1.08232247064989 0.280085765271914 NR1D1 other 1 1 1 0.584434426876725 -1.08232247064989 0.000121218978295186 125.707413770707 91.6677353406245 1.371337617359 0.171412580490313 -733.588880229553 214.001047385577 -3.42796864404037 0.000703392596650385 FRMD8 other 0.888292672947127 1 1 1.371337617359 -3.42796864404037 0.00032009303428208 414.394212025459 274.977624466786 1.50701066251852 0.13296418136409 -1877.09212247985 606.00381244723 -3.09749226642582 0.00215510503425763 PRDX5 other 1 1 1 1.50701066251852 -3.09749226642582 2.7911718212902e-15 121.029743368657 24.3227635564817 4.975986511056 1.15059540587305e-06 -228.925289369449 50.5121923465725 -4.53207985507251 8.74459470401009e-06 BCL2L12 other 3.71700351441216e-11 0.134675503036459 0.0126979708992149 4.975986511056 -4.53207985507251 1.88095099732312e-13 233.152160022173 59.0061970824345 3.95131649810354 9.90293618322832e-05 -594.693873361328 122.540860529536 -4.85302511171766 2.04768249902557e-06 IRF3 other 2.37789825081589e-09 0.0318967502873214 0.929786678243307 3.95131649810354 -4.85302511171766 1.41846191136026e-14 1052.54921109054 153.930089422964 6.83783927519448 5.25547453815472e-11 -580.10901539326 319.673636871161 -1.81469144928915 0.0706687764305248 PRMT1 essential 1.85208571766309e-10 1 7.0854307723402e-07 6.83783927519448 -1.81469144928915 0.00862035247338581 44.1265469284697 72.1677485793738 0.611444139482017 0.541414402804353 -380.960142012683 149.874054771583 -2.54186852149485 0.0115793748237713 RRAS other 1 1 1 0.611444139482017 -2.54186852149485 1.85242022409348e-06 20.4343678908654 10.5193677305065 1.94254715819137 0.0530990649667087 -80.5994159362661 21.8460507143347 -3.68942730153873 0.000271246228365352 PRRG2 other 0.0161568091945434 1 1 1.94254715819137 -3.68942730153873 2.48517043857628e-15 357.125561513383 75.2993233502169 4.74274595871723 3.40147282438769e-06 -748.773712512845 156.37753891742 -4.78824336088484 2.76191333455611e-06 SCAF1 other 3.31372626279762e-11 0.0429560380923512 0.0362392914710264 4.74274595871723 -4.78824336088484 5.5116926831639e-12 152.204090627395 63.9032847496044 2.38178821673697 0.0179141878960576 -742.540697771394 132.710865825508 -5.59517634937071 5.35539905474768e-08 PRR12 other 6.59584263394224e-08 0.000847973886328748 1 2.38178821673697 -5.59517634937071 0.361986104729852 -2.85730245028674 5.69895619864606 -0.501372944569318 0.616512725350312 -16.9037014969837 11.8468617752579 -1.42685057170896 0.154765648571193 TSKS other 1 1 1 -0.501372944569318 -1.42685057170896 0.425277071243013 3.85364861085953 8.16116230034614 0.472193600499293 0.637167213152645 -17.9315505127857 17.8349867931056 -1.00541428602109 0.315590979817335 FLRT1 other 1 1 1 0.472193600499293 -1.00541428602109 0.0006401523197672 113.01273065196 35.2284900266355 3.20799246764518 0.00150831882533364 -119.766329369177 106.047464031262 -1.12936533148845 0.259809197682167 ASL other 1 1 1 3.20799246764518 -1.12936533148845 0.00047662434334991 166.347120565795 62.6216199100774 2.65638482052466 0.00839055210140739 -372.255284420143 188.652380074367 -1.97323396754072 0.0495361482794253 SBDS other 1 1 1 2.65638482052466 -1.97323396754072 0.774749848993225 -35.8974408903018 81.5624609124627 -0.440122091568925 0.660198211901584 -118.768905473163 167.440902850346 -0.709318353230071 0.47873450207311 CSN1S1 other 1 1 1 -0.440122091568925 -0.709318353230071 0.508927102303916 -69.3540856648795 105.085946745934 -0.659974885438837 0.509828402409297 -250.55011439904 215.732649593631 -1.16139172661623 0.246500797055332 STATH other 1 1 1 -0.659974885438837 -1.16139172661623 0.418291930699843 -50.019152014834 49.5943334857817 -1.00856586829973 0.314085872459154 -111.429868021518 91.8586490213377 -1.21305798864551 0.226167862937733 STAT5A other 1 1 1 -1.00856586829973 -1.21305798864551 0.995965333067035 1.12927392243806 12.9799375116829 0.0870014914495259 0.930735294472169 0.419937509717996 24.3800967328743 0.0172246039184803 0.986270250094527 WNK4 other 1 1 1 0.0870014914495259 0.0172246039184803 1.29572946669611e-12 280.647993408483 53.7298868204168 5.22331257362411 3.53324835165557e-07 -292.538966863042 100.835178058225 -2.90115981839317 0.00402642752010912 BECN1 other 1.58960090974278e-08 1 0.00404168278945881 5.22331257362411 -2.90115981839317 3.00379514518721e-16 858.132046689067 115.322531949813 7.44114816229074 1.31410194163067e-12 -96.6222010465085 206.758296349981 -0.467319584037176 0.640645398538326 TRAP1 other 4.10018037318055e-12 1 1.84670745857358e-08 7.44114816229074 -0.467319584037176 0.091186242129588 -30.8270319221192 57.454334278159 -0.536548413786738 0.59201814371376 -234.28763414082 111.063849971934 -2.10948597766083 0.0358163468206434 GLIS2 other 1 1 1 -0.536548413786738 -2.10948597766083 2.31144081278625e-22 301.540748869202 77.250907805391 3.90339424397235 0.000119765734698071 -713.447929770093 112.532040060358 -6.33995375350371 9.56678493841716e-10 DNAJC8 essential 3.47109066856111e-18 1.5237018371417e-05 1 3.90339424397235 -6.33995375350371 1.3396395320305e-05 221.53557039254 126.76082848926 1.74766584466833 0.0816545043425299 -508.327569489334 185.498360769415 -2.74033456350168 0.0065454525578535 AHDC1 other 0.108524198489791 1 1 1.74766584466833 -2.74033456350168 0.0557519925429468 -212.271608171805 513.545439759074 -0.413345327866977 0.679681719243441 -1653.24849901277 750.816636054522 -2.20193376068549 0.0285157031912752 IFI6 other 1 1 1 -0.413345327866977 -2.20193376068549 1.42635913936569e-33 511.441718291146 37.3159940842228 13.7056972711705 7.28552548998272e-33 -197.103691121058 176.61963316229 -1.11597837449898 0.265416312868442 ZNF384 other 2.24951099869362e-29 1 1.15271584302507e-28 13.7056972711705 -1.11597837449898 7.71746998998221e-23 508.236442166545 45.969639056425 11.0559154389425 1.06550752659808e-23 183.547992956243 220.835083212164 0.83115413677229 0.40661825765393 EMG1 other 1.16348577568972e-18 1 1.65835591439725e-19 11.0559154389425 0.83115413677229 6.60726616532903e-16 206.022393908857 33.7922414144025 6.09673656690463 3.69689161222069e-09 -153.266369325322 60.3826999150004 -2.53824968974676 0.0116990169959119 PCNX4 other 8.93764894184057e-12 1 4.67656788945918e-05 6.09673656690463 -2.53824968974676 5.162427365733e-26 182.875463849357 21.6945249971951 8.42956754632799 2.02370875303487e-15 -136.797647876655 40.5371504027115 -3.3746241785043 0.000846398246403125 ATG14 other 7.95426808512141e-22 1 2.97667320483899e-11 8.42956754632799 -3.3746241785043 2.80424607270879e-15 1608.07305874109 227.136095493686 7.07977767798596 1.22278731865436e-11 -407.321366492807 424.413535954469 -0.959727558115641 0.338041557517408 KTN1 other 3.73385364581176e-11 1 1.67827559485311e-07 7.07977767798596 -0.959727558115641 0.00123298049178764 89.5286003406953 45.4362574947516 1.97042197744911 0.049804103855409 -137.852059588995 81.3004339034679 -1.69558823945114 0.091108166059892 SIX1 other 1 1 1 1.97042197744911 -1.69558823945114 0.68034425029188 -15.5530730878511 25.7702174852837 -0.603528980565755 0.546657960570778 -40.7026787106298 47.6238159492735 -0.854670670531406 0.393482880043766 RHOJ other 1 1 1 -0.603528980565755 -0.854670670531406 1.19154627952174e-12 215.909685333958 36.7383771150583 5.87695217613359 1.21469943018113e-08 -109.466331074918 69.0597121704821 -1.58509683337062 0.114101972736757 DLGAP5 other 1.46393375902041e-08 1 0.000150282613502009 5.87695217613359 -1.58509683337062 4.49091402658536e-08 68.042418422577 12.6773549140732 5.36724094921748 1.71374030844161e-07 8.53599966733697 23.5040225152497 0.363171863956422 0.716758580006603 L3HYPDH other 0.000439615574062441 1 0.00199856394770461 5.36724094921748 0.363171863956422 0.000105936960568351 145.344288785433 102.585402527353 1.41681257961316 0.157677843463488 -547.635104552964 190.254731313349 -2.87843093715767 0.0043127073418379 HSPA2 other 0.782768201639543 1 1 1.41681257961316 -2.87843093715767 2.37692973477919e-09 81.0502925725026 23.1619609675523 3.4992845677465 0.000544575263114466 -132.121657607535 42.9561375401044 -3.07573411329602 0.00231296197737327 ZBTB1 other 2.51716858913116e-05 1 1 3.4992845677465 -3.07573411329602 4.57869278568731e-30 178.356099190977 17.3377233789942 10.2871695027196 3.51824622992205e-21 -59.2841638576794 31.0228991411396 -1.91098077545765 0.0570581587480191 TRMT5 essential 7.17343798733631e-26 1 5.41458094785003e-17 10.2871695027196 -1.91098077545765 0.00118312095214859 69.7549527889328 27.1424629451917 2.56995663694145 0.0107020562411398 -53.3859434955917 50.4913443301667 -1.05732862144642 0.291296333792547 SGPP1 other 1 1 1 2.56995663694145 -1.05732862144642 3.66017015811593e-07 418.025048883095 123.113283787626 3.39545040163336 0.000786979253878577 -496.32450228121 228.62991670061 -2.17086420466638 0.0308031484808702 PLEKHG3 other 0.00337980112400425 1 1 3.39545040163336 -2.17086420466638 0.419082998637693 -56.6200499271824 43.1818625908005 -1.31119980774625 0.190900156796081 -16.5124409055951 196.020309290362 -0.0842384187912668 0.932929066986467 PZP other 1 1 1 -1.31119980774625 -0.0842384187912668 3.2713646301878e-23 193.451733469314 30.4704662660276 6.3488274770839 9.37166486651465e-10 -316.603845586763 59.816879340256 -5.2928847020893 2.52744419113021e-07 RHOT1 other 4.94761186669603e-19 0.00398224106754476 1.212131133835e-05 6.3488274770839 -5.2928847020893 0.194866075016536 -43.6356662308538 30.2105509915385 -1.44438498467226 0.149816470005436 -98.9314435877992 60.3608770533501 -1.63899943833418 0.102404495646879 EVI2A other 1 1 1 -1.44438498467226 -1.63899943833418 1.94856687920164e-11 89.2562548670631 17.0451584128687 5.23645792576952 3.43507497526687e-07 -94.2249233651673 42.4431103362682 -2.22002870710092 0.0273000021568847 WDR60 other 2.28664323274312e-07 1 0.0039310998016954 5.23645792576952 -2.22002870710092 3.75063722168724e-08 193.97863119333 43.9775947834897 4.4108513016304 1.48288449410189e-05 -175.542055560212 85.5605427202505 -2.05167066476151 0.0411555946069874 AIF1L other 0.000368837664380724 1 0.150156883872757 4.4108513016304 -2.05167066476151 0.23465601912437 -10.7385895798717 14.7484204827774 -0.72811794269168 0.467165444397022 -48.9556813382047 28.6937670644652 -1.70614340139508 0.0891186472519304 FAM78A other 1 1 1 -0.72811794269168 -1.70614340139508 2.59576740605935e-16 449.320403906932 62.4965332792072 7.18952524773757 6.24231211773327e-12 -272.293199848141 121.59003537662 -2.23943680092472 0.0259328587826089 NUP214 essential 3.5468565836395e-12 1 8.62749957791916e-08 7.18952524773757 -2.23943680092472 1.14606473475004e-18 298.89946553293 74.8693386678814 3.99228136445603 8.41720789682215e-05 -650.94447135725 129.352503365025 -5.03232990799044 8.80258185728072e-07 MAP2K2 other 1.64139391310901e-14 0.0137927655121732 0.795510318328661 3.99228136445603 -5.03232990799044 9.1721033088543e-14 4462.04019034032 649.742837063584 6.86739419938178 4.43382817612564e-11 -1081.17930909971 1067.2439775872 -1.0130573063003 0.311933090395586 CANX other 1.17100242944143e-09 1 5.98836392358891e-07 6.86739419938178 -1.0130573063003 0.792101711130059 2.39399711879542 4.88363799299466 0.490207734936434 0.62439560089947 -5.94140976264021 13.5474000376106 -0.438564576682282 0.661337107178001 RGS13 other 1 1 1 0.490207734936434 -0.438564576682282 2.79992410326337e-13 145.755889145498 34.6687657113434 4.20424223807331 3.56561865957794e-05 -302.148663807323 68.3378230129018 -4.42139726561497 1.42247424937786e-05 IPPK other 3.51838462816076e-09 0.218136426142095 0.349394972452043 4.20424223807331 -4.42139726561497 0.0208507321348684 31.0275561731263 11.9719718499223 2.59168302114974 0.0100744167010991 3.90375283824411 24.1427206505751 0.161694818688594 0.871668018108728 ZNF484 other 1 1 1 2.59168302114974 0.161694818688594 0.141010454989524 -16.1142354200465 9.06625371877814 -1.77738632955643 0.0766345209379096 -27.8820873264092 17.8599185956683 -1.56115422234744 0.119663034007391 OMD other 1 1 1 -1.77738632955643 -1.56115422234744 0.288216742227648 21.4725224369733 21.421175251517 1.00239702933445 0.317056067655598 -29.0829356438704 42.8862745723269 -0.678140872199625 0.498267463697659 FGD3 other 1 1 1 1.00239702933445 -0.678140872199625 0.00610012716723803 28.8454571539991 47.8933871708488 0.60228475908583 0.547488201726564 -232.000904964058 92.1172995978717 -2.51853784226017 0.0123605545255139 HIVEP3 other 1 1 1 0.60228475908583 -2.51853784226017 1.20951756064514e-14 247.197679034127 48.360639979737 5.11154689304571 6.03033815227254e-07 -349.081784268904 93.5409282109852 -3.73186145300522 0.000231410027061519 PPCS other 1.5828956316163e-10 1 0.00678533648893706 5.11154689304571 -3.73186145300522 0.0719624047387273 17.2870231310991 44.0942055137647 0.392047502153151 0.695331249496506 -168.85226407719 88.7495306506113 -1.9025707836352 0.0581564787683924 EDN2 other 1 1 1 0.392047502153151 -1.9025707836352 0.000153577201375083 123.820519106426 31.7071701394653 3.90512677611393 0.00011915605053566 5.3924248460148 73.4668024841345 0.0733994765483269 0.941542782377819 BCL11B og 1 1 1 3.90512677611393 0.0733994765483269 3.69378152359639e-05 151.589137491672 39.5465769440785 3.83317973907146 0.000157565698229227 -68.7781343512421 74.3441939555378 -0.925131213237385 0.355726834813386 TRAF2 other 0.28663744623108 1 1 3.83317973907146 -0.925131213237385 0.000861669447029772 27.7754130028521 16.2006544904158 1.71446240145939 0.0875829098698529 -82.0502984164459 36.0703116244247 -2.27473217505795 0.0237006656897569 ABHD8 other 1 1 1 1.71446240145939 -2.27473217505795 0.629817638886534 14.1969090329242 15.4814263627742 0.917028489510589 0.359949127112224 -28.4734521482679 137.127617494817 -0.207641995598327 0.835665621171495 MASP1 other 1 1 1 0.917028489510589 -0.207641995598327 0.776034253019245 9.59285684606851 20.0011170908494 0.479616053568192 0.631891591859947 90.9720349531082 157.881647924349 0.576203986651436 0.564960885509301 ATP13A4 other 1 1 1 0.479616053568192 0.576203986651436 1.81781318826383e-09 27.4417965189298 4.17022444859047 6.58041236322546 2.44150763330416e-10 11.8502524222528 32.9652611908973 0.359476976494426 0.719520327332491 HRASLS other 1.93760707737041e-05 1 3.22181347290817e-06 6.58041236322546 0.359476976494426 1.14038975742371e-07 41.0546273113391 9.04872731049876 4.53706094819606 8.59162851684583e-06 -75.7236032993114 31.7467015351059 -2.38524317921896 0.0177579398265149 HELB other 0.00108827394550944 1 0.0886827895508827 4.53706094819606 -2.38524317921896 4.90639692336375e-17 510.817044614081 57.1580024976891 8.93692960377216 6.43129869729482e-17 -154.658557150267 241.608465809714 -0.640120604350314 0.522637016906542 RAP1B other 6.82185428224496e-13 1 9.62122285115305e-13 8.93692960377216 -0.640120604350314 0.76596434478965 -37.5399474138171 57.3161650324004 -0.654962651332238 0.513057770711488 -92.4183418658356 194.069711689386 -0.47621208410797 0.634314197442325 TSPAN8 other 1 1 1 -0.654962651332238 -0.47621208410797 0.792846843228924 2.64107206539928 5.26463213904233 0.501663173351312 0.616314799350999 -7.35043840698984 21.6879223076657 -0.338918514310234 0.734935528529227 BEST3 other 1 1 1 0.501663173351312 -0.338918514310234 7.74724494158725e-17 216.359174827861 25.4589584284833 8.49835139311118 1.33743291116077e-15 -174.324336302911 104.879485944763 -1.66213949975615 0.0976496139715377 RAB3IP other 1.07229617236509e-12 1 1.97097488117763e-11 8.49835139311118 -1.66213949975615 0.744574858972523 -5.44019191529258 90.8303982352734 -0.0598939564395736 0.952284730875185 274.501916395522 374.151747195719 0.733664665347479 0.463794455094691 PTPRB other 1 1 1 -0.0598939564395736 0.733664665347479 1.04478858583301e-15 200.192798479898 26.0362690665931 7.68899714347949 2.79872022520728e-13 -292.889162332607 108.705573245766 -2.69433437115899 0.00749665706546853 DYRK2 other 1.4064943942484e-11 1 3.99097504114558e-09 7.68899714347949 -2.69433437115899 5.5180711328354e-22 219.537497482709 20.7552224758344 10.5774581668936 4.19025211819777e-22 -15.3871884691948 87.7329024947714 -0.175386748091593 0.860907210031049 YEATS4 essential 8.25944887162803e-18 1 6.47561562346284e-18 10.5774581668936 -0.175386748091593 0.0522796316497377 13.3737330460751 29.0082162195863 0.461032589692473 0.645149144027429 -150.182311609461 74.1174288792162 -2.02627524835221 0.0437269794985482 LRRC61 other 1 1 1 0.461032589692473 -2.02627524835221 1.16668611929811e-16 91.2758011685555 11.5207220935809 7.92275001750218 6.37745742770559e-14 -27.132144121813 31.5465386923468 -0.860067229131394 0.390526476701859 IDUA other 1.60676012349736e-12 1 9.1739725097545e-10 7.92275001750218 -0.860067229131394 1.40541050658622e-05 120.099542903247 33.5451920972212 3.58023118648932 0.0004071994076639 -129.410642542881 91.4474057616665 -1.41513738377834 0.158184816931641 FGFRL1 other 0.113725818192957 1 1 3.58023118648932 -1.41513738377834 1.73936190723607e-53 233.085842444874 12.9788407331904 17.9589107560901 1.00727314759802e-47 -7.9337839299415 35.5897936999975 -0.222923009804973 0.823767158304471 TMEM175 other 2.77097745441778e-49 1 1.60337739634653e-43 17.9589107560901 -0.222923009804973 9.22456705300828e-19 82.1491804761312 13.6358230208533 6.02451207752553 5.51271149429777e-09 -57.0875295088885 19.5780709894987 -2.9158914348359 0.00384335896761737 AUNIP other 1.3234486350951e-14 1 6.92065800994142e-05 6.02451207752553 -2.9158914348359 1.76168872612535e-16 182.341614252976 30.6911143013894 5.94118585797717 8.62997041984267e-09 -193.003305798174 61.0071400630782 -3.16361831743987 0.00173495233091538 PIN1 other 2.41615608788092e-12 1 0.000107451920444176 5.94118585797717 -3.16361831743987 1.03351388982141e-21 89.089704829214 12.1292823332656 7.34501039561738 2.39976700657142e-12 -80.1327550647724 24.1103277940174 -3.32358629668469 0.00101062428754328 FBXL12 other 1.54220942639151e-17 1 3.35199455477897e-08 7.34501039561738 -3.32358629668469 3.09110685099558e-15 636.316402845151 141.953078040699 4.48258263665626 1.08784693547646e-05 -727.806241862961 214.951790850886 -3.38590452762427 0.000814113645124186 EMC1 essential 4.11271766524962e-11 1 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8.49997081172952e-11 296.345363577593 50.9850773564587 5.81239411496259 1.72650683124194e-08 -107.177980155718 113.239153617118 -0.946474578202039 0.344749735136236 SIN3B other 9.70101668742691e-07 1 0.000211963243671572 5.81239411496259 -0.946474578202039 8.3439573315234e-29 438.961382203577 56.2842179679817 7.79901361431882 1.33836435266252e-13 -716.296948955218 126.651270863374 -5.65566333501644 3.92473305098794e-08 SLC35E1 other 1.3008229479845e-24 0.000621913199259549 1.9162700801422e-09 7.79901361431882 -5.65566333501644 8.84783065285925e-28 251.01322374657 30.6035398167841 8.20209770664849 9.45886609916184e-15 -329.244362683962 68.8355196484607 -4.78305915848961 2.83333902392218e-06 EPS15L1 other 1.37389114377598e-23 0.0440499218049181 1.37872432261383e-10 8.20209770664849 -4.78305915848961 0.551913851349579 -31.0209661880076 38.6084785728243 -0.803475488667472 0.422401541236958 25.6794014549485 86.5248863821123 0.296786306560899 0.766856164270563 KLF2 other 1 1 1 -0.803475488667472 0.296786306560899 0.0339010881324691 -7.0695153456987 9.45456319853232 -0.747735796699327 0.455267880077687 39.6199191970657 21.0274357910969 1.88420117368001 0.0606080908101126 F2RL3 other 1 1 1 -0.747735796699327 1.88420117368001 2.41969955275493e-12 174.451890317985 80.2854927173761 2.1728943102099 0.030661174540304 -705.70510448314 141.242605874081 -4.99640388334582 1.05300684145491e-06 UQCR11 other 2.93896707677614e-08 0.0164848221029766 1 2.1728943102099 -4.99640388334582 1.35648121511914e-17 93.1318614361107 15.8974628047069 5.85828459422698 1.35697366385424e-08 -82.0525232495642 29.1313005163424 -2.81664470158253 0.00521095395030433 GFER other 1.9081621253081e-13 1 0.000167450550119613 5.85828459422698 -2.81664470158253 0.0600301888651833 1.43900531581982 16.5246115706284 0.0870825501506841 0.930670443036266 -57.8949874173729 30.2805190673117 -1.91195492021375 0.0569403003991822 SYNGR3 other 1 1 1 0.0870825501506841 -1.91195492021375 6.52278146648732e-09 391.236368330477 90.2687778121724 4.33412723438602 2.06440927634926e-05 -256.378447350228 163.445994755127 -1.56858201226852 0.117912225263913 PKMYT1 essential 6.72107402306854e-05 1 0.206440927634926 4.33412723438602 -1.56858201226852 0.00503627238151239 7.85779470298848 4.47658915796907 1.7553084336543 0.0803406275796105 -10.7831678315429 8.20337998052938 -1.31447864869561 0.189800686282873 WFIKKN1 other 1 1 1 1.7553084336543 -1.31447864869561 1.22095042909278e-20 118.322861310146 17.6643221470305 6.69840938844272 1.21311884375692e-10 -93.4546493524846 32.3347027988398 -2.89022756553178 0.0041611282041761 WDR24 essential 1.79931464735403e-16 1 1.61793660191861e-06 6.69840938844272 -2.89022756553178 0.0398398862458103 -11.6581491070886 22.2470896544831 -0.524030301857455 0.600685775038933 -96.2875649877071 40.7235005186872 -2.36442260025075 0.0187634459469696 FBXL16 other 1 1 1 -0.524030301857455 -2.36442260025075 8.61441975860763e-09 315.653891735415 56.0203066807514 5.63463341131393 4.39222168515391e-08 82.4405277512584 102.545682316288 0.80393953103732 0.422136530827352 CHTF18 other 8.81255141305561e-05 1 0.000528999179759937 5.63463341131393 0.80393953103732 9.60422237478556e-13 893.77386140911 226.865229541223 3.93966877699391 0.000103955281779426 -1779.68175911987 441.258326788515 -4.03319699839416 7.16632098188827e-05 SMARCA4 other 1.18477687215355e-08 1 0.973333303300767 3.93966877699391 -4.03319699839416 1.28422303737574e-13 150.918807748837 55.3909471547017 2.72461143022766 0.00685493884793103 -486.49023958128 101.972171247365 -4.77081377821353 2.99697301225514e-06 KDM4B other 1.63147694668214e-09 0.0465849485024939 1 2.72461143022766 -4.77081377821353 3.01463901640915e-09 52.031542068801 36.3308603741294 1.43215826801206 0.153242488888391 -293.019179721742 66.7784295288174 -4.38793157894337 1.63652949428146e-05 TICAM1 other 3.16989292575422e-05 0.250650857344148 1 1.43215826801206 -4.38793157894337 0.0179141697270164 10.3426645695197 4.98945742195898 2.07290366363301 0.039147837817412 -15.0834790921739 11.3988064135454 -1.32325074617022 0.186892563042462 METTL25 other 1 1 1 2.07290366363301 -1.32325074617022 5.50292012165824e-18 146.267014878126 15.9474904836163 9.17178881708028 1.17277516587904e-17 -7.87796771130095 47.8424714508488 -0.164664731406997 0.869329733813449 EMC6 other 7.7948863523289e-14 1 1.7665512323636e-13 9.17178881708028 -0.164664731406997 4.62170582852954e-25 291.042463464148 26.5985980232298 10.9420227039774 2.47517336024752e-23 -104.111586144875 81.4277788130036 -1.27857578411864 0.202136343453462 METTL16 other 7.0799911587244e-21 1 3.84839954051284e-19 10.9420227039774 -1.27857578411864 9.36712647206915e-05 7.5473914270086 252.259091762656 0.029919204791674 0.976153592861556 -1372.49527700878 374.275909579031 -3.66706817586123 0.000295445148129781 TUBA4A other 0.696820538257224 1 1 0.029919204791674 -3.66706817586123 0.0615280321295225 404.236947815821 219.891414834463 1.83834802336478 0.0671095247074743 -81.4726843305041 327.830627170102 -0.248520661519005 0.803920508131624 VIL1 other 1 1 1 1.83834802336478 -0.248520661519005 4.91651800763445e-17 540.990950529726 121.19391940554 4.46384565482577 1.18197010096472e-05 -792.13869066201 180.512440087924 -4.38827756289913 1.63823270855764e-05 AAMP essential 6.83543498601418e-13 0.250895339315602 0.120678550579506 4.46384565482577 -4.38827756289913 3.22120855733766e-06 139.203186886623 126.939767820477 1.09660817312577 0.27378621164434 -682.5995075898 189.070601444889 -3.61028897339583 0.000364277002829422 PNKD other 0.027483351411205 1 1 1.09660817312577 -3.61028897339583 0.0355526794897855 361.457035250864 194.331907355299 1.8599983922867 0.0639691130145697 -132.104521004943 298.304071814551 -0.442851886671762 0.658226150972746 TNFRSF19 other 1 1 1 1.8599983922867 -0.442851886671762 1.52388951002014e-16 191.817050729572 45.374457677441 4.22742354505183 3.23446204395821e-05 -313.576193124816 71.8364177384805 -4.36514240265133 1.80883406610225e-05 RNF6 other 2.09351940886567e-12 0.276624993729017 0.317915274300652 4.22742354505183 -4.36514240265133 2.34517177650861e-14 988.448084048257 142.77646104466 6.92304653593475 3.37534171757969e-11 105.467480890068 199.450660671729 0.528789829699557 0.597397224381742 ECHS1 other 3.04637813768468e-10 1 4.57358802732048e-07 6.92304653593475 0.528789829699557 0.804068514090683 0.210379387095557 2.07777976081092 0.101252014801343 0.91942500314849 -2.63446424304917 4.74018593239031 -0.555772343242388 0.578823345382807 ZNF835 other 1 1 1 0.101252014801343 -0.555772343242388 2.19301746568727e-51 574.090936092271 30.1013999405385 19.0719015469817 6.96335165772963e-52 -258.018707571238 276.187665770485 -0.93421517159877 0.35103073848162 AKAP9 other 3.49238031410697e-47 1 1.10919228555975e-47 19.0719015469817 -0.93421517159877 0.749506507995651 23.7118635059431 49.2292676998652 0.481661918079029 0.630443652539338 -115.099096785397 227.241812768525 -0.506504922589401 0.61292338047829 GNG11 other 1 1 1 0.481661918079029 -0.506504922589401 2.03091006958327e-11 821.508519513153 117.043069380164 7.0188565958129 1.88597486647312e-11 -408.518020468608 483.915542804979 -0.844192807076758 0.399325992479259 SEM1 other 2.38042969255855e-07 1 2.57548727765569e-07 7.0188565958129 -0.844192807076758 9.55387630706539e-17 19.2773317205532 2.22159085388609 8.67726462180584 4.24219927645874e-16 -18.1036647160744 10.2395248981889 -1.76801803756309 0.0782128677444286 GNGT1 other 1.31872154666424e-12 1 6.29372684655419e-12 8.67726462180584 -1.76801803756309 4.46484105214865e-05 239.746300307833 61.2758903019173 3.91257147185557 0.000115538079958921 -198.628172386273 195.065201139397 -1.01826554006591 0.309459968439281 HIP1 og 0.343480222141796 1 1 3.91257147185557 -1.01826554006591 6.96955010535165e-07 357.675443840322 82.9744487569135 4.31066972060505 2.28303428005126e-05 -454.135192874155 259.404052137997 -1.75068657999438 0.0811356378183844 PTPN12 other 0.00628583724001666 1 0.227641348063911 4.31066972060505 -1.75068657999438 0.215848493357621 -73.1834815311114 52.5987983414549 -1.39135272741455 0.165259597680414 -258.351230248718 177.950262751128 -1.4518170766066 0.147709168411229 FGL2 other 1 1 1 -1.39135272741455 -1.4518170766066 1.09513553362658e-05 102.428953555896 26.6848143229161 3.83847353466248 0.000154259208615126 -151.831104327971 87.25205904529 -1.74014351052919 0.0829732066350109 STYXL1 other 0.0893740108992652 1 1 3.83847353466248 -1.74014351052919 0.927515764456974 -71.0780683729476 219.512328784883 -0.3237998920899 0.74634786168634 -225.66555277298 755.536892688877 -0.298682374026581 0.765419165499212 STEAP4 other 1 1 1 -0.3237998920899 -0.298682374026581 7.47907621803266e-06 251.564364636016 58.8677599363347 4.27338096282383 2.67479970581364e-05 -167.260454297143 176.994473796512 -0.945003822489057 0.34550495540561 GNAI1 other 0.0618893557042202 1 0.265179642834364 4.27338096282383 -0.945003822489057 3.65285664393626e-09 20.2258963850099 3.51127266546616 5.76027506605634 2.28298561446065e-08 -11.3265982771738 11.1776825369055 -1.01332259524965 0.311813296187267 PMS2P3 other 3.81760047857778e-05 1 0.000278387265827332 5.76027506605634 -1.01332259524965 5.8307440880571e-79 260.568900502889 9.49295103398454 27.4486721326233 7.74660791965293e-80 4.1193306070753 87.0865529192692 0.047301569174451 0.96230810657923 PEX1 other 9.30994908540077e-75 1 1.23705581868938e-75 27.4486721326233 0.047301569174451 6.39472312598398e-82 156.815528934211 5.53054845565545 28.3544263632395 8.63498064579677e-83 2.39223574163982 50.7441272304732 0.0471431054627188 0.96243415269033 MTERF1 other 1.02117333598838e-77 1 1.37900640913374e-78 28.3544263632395 0.0471431054627188 6.52430072250837e-06 168.936817679214 35.2367910496021 4.79433037592455 2.72421323987553e-06 -95.5915341608134 160.105839249211 -0.597052141315231 0.550982335115262 SGCE other 0.0542038904025996 1 0.0292716712624626 4.79433037592455 -0.597052141315231 1.68288712833738e-77 106.587570622598 3.95760874036496 26.9323163594915 3.26232318604497e-78 -16.94620684366 36.3063605582395 -0.466755868203214 0.641053764182288 RBM48 essential 2.68672930039062e-73 1 5.208951431158e-74 26.9323163594915 -0.466755868203214 3.3826891809329e-08 148.672876361402 24.9911547183651 5.94901988470933 8.53505723437761e-09 -27.2123901376585 115.372944127522 -0.235864572438929 0.813720635441532 CASD1 other 0.000333566980131793 1 0.000106321207968642 5.94901988470933 -0.235864572438929 1.71733696718919e-41 111.485374893453 6.90649872220014 16.142097374911 1.41998261056694e-41 3.38688479243901 44.8463863486066 0.0755219108650488 0.939854980473163 ZNF780B other 2.72661590280628e-37 1 2.25663636471299e-37 16.142097374911 0.0755219108650488 5.41819531843269e-09 28.5557950044522 5.09530582850716 5.60433386445393 5.17110185328588e-08 -81.9345140317479 38.5765269219853 -2.12394739934591 0.0345870235273414 LRFN1 other 5.60999943270521e-05 1 0.000620687355449904 5.60433386445393 -2.12394739934591 0.0474636079167556 480.756873253063 197.037286323237 2.43992841265783 0.0153338998527595 1259.73173296785 1486.69506828951 0.847336995889286 0.397557772153139 ZFP36 other 1 1 1 2.43992841265783 0.847336995889286 7.91040054218543e-06 271.185250855033 80.2406909138992 3.37964750510465 0.000841399772902188 -327.031743517421 177.238993431574 -1.84514556975114 0.066194306650111 SRD5A3 other 0.0653715500806204 1 1 3.37964750510465 -1.84514556975114 0.00017368229779585 8.87370728434881 2.54242533746756 3.4902528517072 0.000567037104036146 -3.5875088950122 5.5831020919552 -0.642565519298225 0.521074455301818 SPINK2 other 1 1 1 3.4902528517072 -0.642565519298225 4.71932667726353e-10 151.464153275649 22.1936905047284 6.82464925080305 7.25276951440557e-11 115.133405604067 44.9931454209367 2.55890990787436 0.0111200152711955 RASL11B other 5.19267514299306e-06 1 9.73249141138083e-07 6.82464925080305 2.55890990787436 1.3759129897598e-36 2662.4907917814 178.380785376286 14.9258833352763 8.9869852364526e-37 1539.99134868676 393.02180123333 3.918335684825 0.000114154272194752 PAICS essential 2.17793267149079e-32 1 1.4257852077632e-32 14.9258833352763 3.918335684825 0.122232390065099 -80.7865479607703 63.2980850549408 -1.27628739306489 0.203047861219515 -280.990206060364 140.289005643933 -2.00293818300734 0.0462722890266517 KDR og 1 1 1 -1.27628739306489 -2.00293818300734 2.13604782895454e-29 349.199067295045 28.3555911429936 12.3149986728924 9.65693403159929e-28 80.2719209010801 62.4751454174098 1.28486168963299 0.199988507354165 PPAT essential 3.33864275665595e-25 1 1.51758718306583e-23 12.3149986728924 1.28486168963299 1.95466594816214e-07 180.488695332181 56.7951265397827 3.177890539706 0.00165868948719779 -356.810697329418 121.119770629425 -2.94593273645726 0.00350501309439991 TUBGCP6 essential 0.00183699505808278 1 1 3.177890539706 -2.94593273645726 5.81768577006768e-06 119.440353216235 32.1011263089343 3.7207527258317 0.000242871121287099 -95.4557487130127 67.7419164475118 -1.40910906745566 0.159984165997569 ADM2 other 0.048566040808525 1 1 3.7207527258317 -1.40910906745566 3.4780065905409e-31 414.87146338621 31.7120154144499 13.0824691513353 3.0415169258903e-30 -54.4673760854819 130.571272051259 -0.417146706391124 0.676923453117209 DGCR6L other 5.46151374912637e-27 1 4.79890540566971e-26 13.0824691513353 -0.417146706391124 0.0234788145357166 8.95191983928817 8.39043340611897 1.06691983667491 0.286950631345293 -47.9056251846912 23.8367881283699 -2.00973490751781 0.0454430839694398 ASPHD2 other 1 1 1 1.06691983667491 -2.00973490751781 0.57970588759811 -2.34224980056164 5.92750579824667 -0.395149305674989 0.693043551531115 -17.3547122162858 16.6067072584652 -1.04504234019295 0.296934655520244 VPREB3 other 1 1 1 -0.395149305674989 -1.04504234019295 4.85058233856623e-07 97.0420443050061 19.4697814329484 4.98423901876903 1.12242543645825e-06 -59.4912712478279 67.5533973197389 -0.880655505247916 0.379299288296771 SDF2L1 other 0.0044348874321511 1 0.0123960665202449 4.98423901876903 -0.880655505247916 0.192461342599195 2.73035559475996 1.7260447877999 1.58185674790062 0.114840088139985 7.35999598969116 5.47641491151524 1.3439441876866 0.180082271209567 GAL3ST1 other 1 1 1 1.58185674790062 1.3439441876866 2.9820391520085e-10 435.664154277094 91.5779345719145 4.75730487167709 3.19896034268189e-06 -737.15448579432 238.572415210328 -3.08985632368452 0.00221169756945352 YWHAH other 3.31483472137265e-06 1 0.0341776923012133 4.75730487167709 -3.08985632368452 0.147634987931643 0.905476628729251 1.44561286580192 0.626361766797753 0.531604914759907 -6.44557444711754 4.1963114010641 -1.53600956437195 0.125702706868856 POM121L9P other 1 1 1 0.626361766797753 -1.53600956437195 3.97226603954784e-09 81.0360749632705 12.8778313127192 6.29268026544441 1.24298688370241e-09 20.7915990502705 43.7023074176199 0.475755178132487 0.634630674461039 GNAZ other 4.14227902604049e-05 1 1.60134000227382e-05 6.29268026544441 0.475755178132487 0.350582870705927 65.923420421221 93.7936639864824 0.702855796642318 0.482746730206501 -223.703156935928 233.294738820798 -0.958886420099522 0.338467518631537 MGAT3 other 1 1 1 0.702855796642318 -0.958886420099522 0.909258707562126 -1.69965990899088 17.5178541976976 -0.0970244351739305 0.922778705253377 -22.0160389128882 50.8506620485833 -0.432954813682737 0.665391970652799 ADORA2A other 1 1 1 -0.0970244351739305 -0.432954813682737 3.10125335244089e-09 1330.63349773394 229.295223715672 5.80314529091079 1.80708364676733e-08 -450.554570633017 570.330308636983 -0.789988825440095 0.430222454140129 ATF4 essential 3.25693627073342e-05 1 0.000221512313420739 5.80314529091079 -0.789988825440095 9.47924854419976e-05 426.080285466962 116.523000846837 3.65661957184765 0.000307149300768597 -237.598894365795 264.95709447978 -0.896744791198363 0.370653967682539 A4GALT other 0.704592544290368 1 1 3.65661957184765 -0.896744791198363 0.0011901552012943 276.680749958364 110.42734124184 2.50554569952403 0.0128109333893784 -468.794298496511 267.797450770098 -1.75055549314757 0.0811499276964848 CDC42EP1 other 1 1 1 2.50554569952403 -1.75055549314757 0.467205832900868 -56.4476191345621 56.3731047894705 -1.00132180665532 0.317561207005509 39.744417684091 133.639573172343 0.297400064521579 0.766388101261712 APOL3 other 1 1 1 -1.00132180665532 0.297400064521579 0.267083111041077 -4.40085821871645 3.14995962776055 -1.39711575346292 0.163521656494179 2.11197603041964 7.80431738157538 0.270616368755792 0.786892093953964 MCHR1 other 1 1 1 -1.39711575346292 0.270616368755792 8.20500564166847e-09 195.721905102631 42.0032477061808 4.65968504320751 4.95539549968581e-06 -280.134697749735 118.519339830131 -2.36362013280904 0.0187980832343293 TPST2 other 8.40520777932518e-05 1 0.0521505822386935 4.65968504320751 -2.36362013280904 0.725187405580636 7.17233244387291 14.3845750111525 0.498612745827537 0.618455191188923 -15.0867468362631 34.9661774998965 -0.431466860691527 0.666470721933963 BAIAP2L2 other 1 1 1 0.498612745827537 -0.431466860691527 0.0022232623669686 168.668052688035 54.2323231724326 3.11010192485674 0.00206822866163246 -51.4228851800162 127.789941389792 -0.402401664957049 0.687703340155971 MPST other 1 1 1 3.11010192485674 -0.402401664957049 0.181504976919552 63.3035184950229 48.2169044754448 1.3128905553707 0.190322369228934 -82.4444229780941 113.615553169708 -0.725643810886936 0.468678744833765 TST other 1 1 1 1.3128905553707 -0.725643810886936 0.00539992310019722 -29.9114363066304 9.22568537690101 -3.24219123941965 0.00133455759890544 -38.6594372373781 25.8488039962714 -1.4955986839064 0.13592186133088 IGLL1 other 1 1 1 -3.24219123941965 -1.4955986839064 0.2075528319743 -33.1260601517995 78.8020847046702 -0.420370352839615 0.674548047970787 -330.817329116011 187.884338157619 -1.76074989730375 0.0794086256708232 APOL2 other 1 1 1 -0.420370352839615 -1.76074989730375 0.239479067575872 31.4576274488288 99.1235765844423 0.317357671431785 0.75121480196059 -335.470746202363 234.123948135786 -1.43287668294317 0.153037207878435 RAC2 other 1 1 1 0.317357671431785 -1.43287668294317 0.258069518655301 -61.6937573435137 61.6733018767009 -1.00033167458512 0.318039098064956 -257.830327187321 163.326454686705 -1.57861950583508 0.115585577757028 LIF other 1 1 1 -1.00033167458512 -1.57861950583508 3.99784833287412e-06 48.9147560380833 17.8462652420601 2.74089594515277 0.00653306687242377 -137.723821322358 43.3808908278697 -3.17475779528895 0.00167201909592895 C22orf23 other 0.0338737689244424 1 1 2.74089594515277 -3.17475779528895 1.9088130232491e-05 56.7627372627372 13.0601652542302 4.34624954261982 1.95587594599205e-05 -14.7407361157361 32.8449300081486 -0.448797915297096 0.653933474727859 APOBEC3F other 0.152666865599463 1 0.196037446066784 4.34624954261982 -0.448797915297096 0.0465095596626884 12.1299032070606 5.94502739454439 2.04034437556872 0.042278185466638 -6.7213275887117 13.2801852435197 -0.506117005558451 0.613182964100375 RIBC2 other 1 1 1 2.04034437556872 -0.506117005558451 0.917889415203316 -3011.18574829093 8023.63196041266 -0.375289614871126 0.707737568245561 -4950.91574573526 15373.0208296016 -0.322052236877349 0.747660496714253 KRT17 other 1 1 1 -0.375289614871126 -0.322052236877349 1.58150599716476e-14 319.127592059627 72.3984380506047 4.40793476561697 1.51341370321146e-05 -508.404594986839 129.05901148525 -3.93931883667762 0.000104372078585377 EMC4 other 2.06228382030284e-10 1 0.153112064353903 4.40793476561697 -3.93931883667762 0.000843237120040706 7.13400212781363 2.79379070102914 2.55352060739042 0.0112119766314494 -6.6209836589111 7.19758293208201 -0.919889874335339 0.358448394522813 RNF112 other 1 1 1 2.55352060739042 -0.919889874335339 1.31994362856766e-07 133.997043701799 40.8746019419876 3.27824706138981 0.00118094678979527 -220.483075389538 101.735983788487 -2.16720836796479 0.0310900343602351 SPECC1 other 0.00125421043586499 1 1 3.27824706138981 -2.16720836796479 0.0863162885404729 18.9916618184045 42.0173406130309 0.451995807952554 0.651632232002832 246.90076117974 112.789746313157 2.18903552184813 0.0294443311208704 CPA4 other 1 1 1 0.451995807952554 2.18903552184813 0.213217571129187 -20.3926150750049 41.1952406974587 -0.495023568979 0.6209890812648 -207.470548980031 117.843013830873 -1.76056723462446 0.079452256293055 DOCK4 other 1 1 1 -0.495023568979 -1.76056723462446 1.73239142342658e-14 164.789919902452 23.7371559952107 6.94227732824021 2.81214922875936e-11 -114.455301037208 65.0544856031685 -1.75937600575899 0.0796337878551873 POT1 other 2.25661306815546e-10 1 3.81833622280946e-07 6.94227732824021 -1.75937600575899 1.60172254292915e-13 658.465091530634 100.327126341199 6.56318102136491 2.65379063651918e-10 -510.899265901184 270.127346412492 -1.89132745235288 0.0596430554349865 ATP6V1F essential 2.02858160061977e-09 1 3.49716530080498e-06 6.56318102136491 -1.89132745235288 4.46259390924902e-17 195.293183997929 23.742398437056 8.2255036076357 8.48800795568786e-15 -97.5841762134241 68.3663583706605 -1.42737127644497 0.154637013859633 LSM8 other 6.21282324045649e-13 1 1.23763644001885e-10 8.2255036076357 -1.42737127644497 0.528250279340463 -19.4930738846523 41.9939687684342 -0.464187464446198 0.642887486098186 -172.109254988812 154.092680653276 -1.11692037713378 0.265021303683186 CDHR3 other 1 1 1 -0.464187464446198 -1.11692037713378 1.89855535295334e-14 143.24026996497 19.7435839774832 7.25502877939135 4.3302574447231e-12 -184.373194813691 80.3221955884595 -2.29542025666665 0.0224816479998903 PRKRIP1 essential 2.469830658657e-10 1 6.01169641050908e-08 7.25502877939135 -2.29542025666665 0.91702618842606 6.02863993138757 40.9342484788932 0.147276184501008 0.883023135690484 -60.1291609638074 177.243621397113 -0.339245838523512 0.734686312997428 VGF other 1 1 1 0.147276184501008 -0.339245838523512 0.146965086723194 -72.5300225844538 165.320331621525 -0.438724153726597 0.661209698102865 -861.579864169886 443.779591757788 -1.94145895884309 0.0532352658017094 PODXL other 1 1 1 -0.438724153726597 -1.94145895884309 0.000116320037300269 52.2187308719547 16.7879072090062 3.11049675351678 0.00207170568801145 -89.5585546369838 48.460710441376 -1.84806524339598 0.065707076832941 FOXP2 other 0.854719634082377 1 1 3.11049675351678 -1.84806524339598 0.0155670837836768 47.019536086808 16.1782126722882 2.90634923889634 0.00395882647270766 51.3965701736061 43.7354249723843 1.17517024714083 0.240958086249363 STRIP2 other 1 1 1 2.90634923889634 1.17517024714083 7.65686229621112e-13 99.9225397310779 14.39313158366 6.94237658776889 2.84769722582496e-11 -111.559833231309 61.2301659665661 -1.82197502603904 0.0695609517790912 IFT22 other 9.47842983647975e-09 1 3.86603375377997e-07 6.94237658776889 -1.82197502603904 1.22443588461739e-22 242.329336561845 30.5763958029551 7.9253728308431 5.882181018315e-14 -345.184370052946 82.0781105007971 -4.20555941099051 3.5384716961416e-05 MKLN1 other 1.84265356276071e-18 0.536538463285951 8.46739957586445e-10 7.9253728308431 -4.20555941099051 0.229416343469894 46.0528128104753 50.1703302811517 0.917929233321724 0.359487461828125 -185.13499648041 162.11709158921 -1.14198320896063 0.254487928431578 DNAJB9 other 1 1 1 0.917929233321724 -1.14198320896063 0.32322056068427 -40.2340396780988 43.3685813176791 -0.927723214724977 0.354373648637888 -169.450012904385 116.768417637896 -1.45116304846964 0.147886777871773 FLNC other 1 1 1 -0.927723214724977 -1.45116304846964 3.86336258048479e-05 428.951913308501 116.770293889515 3.67346778894265 0.000288101140732013 -347.059363359295 313.201674871971 -1.10810187557638 0.268796700221607 LRRC4 other 0.299256065484352 1 1 3.67346778894265 -1.10810187557638 6.70178401717288e-12 1737.53573734598 257.946267900029 6.73603751467877 9.66571955445961e-11 -363.534939364993 694.511478659065 -0.523439785425709 0.601094425111691 CALU other 7.99723886769239e-08 1 1.29259667601788e-06 6.73603751467877 -0.523439785425709 1.30552472442377e-08 43.6942908938729 7.56051222029784 5.77927653850833 2.0507899119129e-08 1.15561284596468 20.3564198245118 0.0567689631048566 0.954770917041827 CCDC136 other 0.000132014660133731 1 0.000250688558832233 5.77927653850833 0.0567689631048566 1.16083505420099e-09 483.2635258651 79.4232643815598 6.08465957208002 3.96698836771242e-09 -49.4024300760762 214.709145613565 -0.230090012863221 0.818195408418075 SMO og 1.24905851832027e-05 1 5.01308320027819e-05 6.08465957208002 -0.230090012863221 3.25751899806956e-05 67.2013811281397 34.1923108689771 1.96539454106075 0.0503859539731601 -287.61506732906 92.0616242045693 -3.12415808230749 0.00197592718711698 IRF5 other 0.25428193298931 1 1 1.96539454106075 -3.12415808230749 0.0990353049474792 43.3184726169789 20.1401431499043 2.15085227024241 0.0323787461948689 28.9175304939287 79.8702142162163 0.362056503512639 0.717594062798858 LRRC17 other 1 1 1 2.15085227024241 0.362056503512639 2.7825052634707e-12 180.574147936724 30.5550860151828 5.90979020144133 1.02209010958743e-08 -191.634852013213 82.0209073194021 -2.33641468103927 0.0201960458294718 KLHDC10 other 3.37072687616841e-08 1 0.000126851603500896 5.90979020144133 -2.33641468103927 5.59420045553071e-09 178.240525826652 37.3847663520004 4.76773143767729 3.04478949551755e-06 -216.796062254231 101.810830119631 -2.12940079163964 0.0341225306228767 NDUFA5 other 5.78720037124652e-05 1 0.0325853371810289 4.76773143767729 -2.12940079163964 0.00235211888483377 67.706683308748 19.67610207391 3.44106180453929 0.000671953062529696 31.9591018615545 53.8166639712728 0.593851411499868 0.553112406374607 FEZF1 other 1 1 1 3.44106180453929 0.593851411499868 0.0154546123768872 1.34129244208708 1.25900034070854 1.06536304933184 0.287656448779319 -7.09857920686868 3.38981523313466 -2.09409030246891 0.0371775126856306 OPN1SW other 1 1 1 1.06536304933184 -2.09409030246891 5.43542605935147e-36 407.019897436263 28.5714819156856 14.2456698129057 1.23088665409324e-34 -247.483874590903 144.279041973235 -1.71531409694842 0.087447803525979 MRPS12 essential 8.59666985547028e-32 1 1.95083225807238e-30 14.2456698129057 -1.71531409694842 1.84616953797777e-05 790.56948941514 190.887805365024 4.14154004182393 4.62731349437309e-05 -483.081516119684 479.008338851587 -1.00850335356971 0.314122544256607 MYO1B other 0.14782279490588 1 0.448155311930034 4.14154004182393 -1.00850335356971 0.323104933032655 0.638336205545975 4.22630149587384 0.151038965433296 0.880059027807005 -16.7585774714084 12.1963884976234 -1.37406064710665 0.170575222036994 HOXD3 other 1 1 1 0.151038965433296 -1.37406064710665 1.86734896334029e-14 236.529847100199 32.7646858121778 7.21904822942901 5.40560672740974e-12 -182.455084607141 96.0871385349239 -1.898850224797 0.0586581207809869 MTX2 other 2.42960773620205e-10 1 7.48514363544427e-08 7.21904822942901 -1.898850224797 0.827530243373326 1.34042874700301 4.39601564592021 0.304919011889098 0.760666278040648 -5.37891523784579 13.0678026109017 -0.411615892740719 0.680952445955194 PDE11A other 1 1 1 0.304919011889098 -0.411615892740719 0.161513227942093 -44.9847210927182 29.5894494808663 -1.52029597988321 0.129606769996003 53.6241594305551 85.7920363587053 0.625048217836293 0.532467298121286 CHN1 other 1 1 1 -1.52029597988321 0.625048217836293 0.386062395306564 36.5371535347244 26.7270578706941 1.36704734623211 0.172743354796053 22.1365306758019 73.1950624576257 0.302432021130076 0.762554738581914 GAD1 other 1 1 1 1.36704734623211 0.302432021130076 8.5991594264844e-11 52.6815225124504 7.84942009610867 6.71151777678037 1.13660755830917e-10 -7.10125751877967 19.8925941953076 -0.356979961942559 0.721386683404433 OSGEPL1 other 9.80906115779075e-07 1 1.51634814354026e-06 6.71151777678037 -0.356979961942559 3.84598377440234e-09 150.106260798862 27.1152694167938 5.53585725044994 7.3551498125878e-08 -111.205114464084 68.7175669540373 -1.6182923725816 0.106771489250125 ORMDL1 other 4.01328406858885e-05 1 0.000875630585188577 5.53585725044994 -1.6182923725816 2.29614885665853e-13 326.882843269841 42.8723600653746 7.62455910454634 4.18553556873633e-13 14.0310801839235 126.99893643868 0.110481871560383 0.912109303361947 HAT1 other 2.89383640404675e-09 1 5.95015736451556e-09 7.62455910454634 0.110481871560383 0.227305137310506 -6.78233924934539 11.4592008023534 -0.591868435358293 0.554439513030661 -57.0583066627873 33.0693077609887 -1.72541581684083 0.0856096008477675 HOXD9 other 1 1 1 -0.591868435358293 -1.72541581684083 0.154379866435908 14.7897585103288 27.2230657613837 0.543280416686509 0.587390018167508 -125.286616235089 78.5611453528198 -1.59476565256812 0.111947638957318 HOXD10 other 1 1 1 0.543280416686509 -1.59476565256812 0.0551308120346009 15.0404870079004 15.9052184330611 0.945632219463066 0.34519117851193 -83.2985385286811 45.8997597162823 -1.81479247480967 0.0706778685448172 HOXD11 other 1 1 1 0.945632219463066 -1.81479247480967 0.0642724319110878 46.8842281954299 21.1539960977375 2.2163296229616 0.0275120663121787 -3.31653946867833 61.0468408221952 -0.0543277821425365 0.956714643251179 HOXD13 other 1 1 1 2.2163296229616 -0.0543277821425365 6.87132764042685e-11 495.979799704489 109.831273433662 4.51583400791632 9.41838924252706e-06 -470.534996389569 202.761835771097 -2.3206290010156 0.0210494261431195 HERC2 other 7.87385434316512e-07 1 0.0969152253056035 4.51583400791632 -2.3206290010156 0.0146319209526615 -80.4355138910148 158.521230539873 -0.507411616835657 0.612283329068934 -803.481555346922 294.715763081101 -2.72629311356453 0.00682734775952302 SNRPN other 1 1 1 -0.507411616835657 -2.72629311356453 2.1281943270936e-16 245.030782338124 36.0596558830832 6.79515032346928 7.82131983925634e-11 -240.945214105794 81.8408612418989 -2.94406987474908 0.00354299998834912 PSMG2 essential 2.91371085322385e-12 1 1.04876077724588e-06 6.79515032346928 -2.94406987474908 0.000160720315167271 346.775569767684 87.0884610985037 3.9818773393579 8.82055258808419e-05 50.7088964390821 191.726277604516 0.264485896626451 0.791609578075999 TWSG1 other 1 1 0.831337081426935 3.9818773393579 0.264485896626451 0.00572072074264625 20.3696759132783 14.6419125763474 1.3911895599065 0.165309006412163 -34.9319976045157 22.8252117709431 -1.53041285903795 0.127081002513719 ARHGAP22 other 1 1 1 1.3911895599065 -1.53041285903795 6.99864630671532e-14 357.371427438855 67.1607016971247 5.32113897574354 2.1520046898189e-07 -318.004525724602 116.49788697723 -2.72970209139294 0.00675127552904131 EIF2AK4 other 8.96456605427166e-10 1 0.00249438863596909 5.32113897574354 -2.72970209139294 0.000177917198329724 63.7742446177131 48.2836030805778 1.32082613037979 0.187673600879022 -289.410651094391 94.1627195111762 -3.07351627689598 0.00233125888478798 MYO5C other 1 1 1 1.32082613037979 -3.07351627689598 0.461681306053381 -35.8980076047067 90.2388561565815 -0.397810977816661 0.691082707457297 -216.580713159829 174.759672223712 -1.23930601610755 0.216304391494905 CGNL1 other 1 1 1 -0.397810977816661 -1.23930601610755 0.0661500585067277 49.2556632866342 22.3874511597076 2.20014609681353 0.0286468919811693 9.1106648358909 43.7141605099877 0.208414498405141 0.835063054490793 TMOD2 other 1 1 1 2.20014609681353 0.208414498405141 3.66738471671583e-09 103.408427268686 25.7804362730295 4.01112014449765 7.81453482026121e-05 -109.974899550406 45.6077663854761 -2.41131956827046 0.0165578923289934 TTBK2 other 3.83241702896804e-05 1 0.741521209094586 4.01112014449765 -2.41131956827046 4.68798551450763e-07 61.3880781440308 14.5645176794737 4.21490635632564 3.40742999193272e-05 -28.8766163178334 26.1651134631747 -1.10363046422386 0.270732480711948 ELL3 other 0.00429278833563463 1 0.334405179408278 4.21490635632564 -1.10363046422386 1.28326101567379e-10 168.169945782188 34.4159815499934 4.88639109530845 1.75966500104332e-06 -113.001139018241 59.6210889100656 -1.89532162333861 0.059113873066079 INO80 essential 1.45200983923489e-06 1 0.0191733098513681 4.88639109530845 -1.89532162333861 1.30114978847052e-16 255.130127607069 34.7818663066227 7.3351477277828 2.55198586317712e-12 -136.929890004352 68.211815824715 -2.00742185717828 0.04569382665863 ICE2 other 1.79051222391428e-12 1 3.56308266216789e-08 7.3351477277828 -2.00742185717828 0.796519463927674 5.50511719695461 30.6855713045317 0.179404096548192 0.857754477108086 -24.9750082264946 53.1586516672802 -0.469820197525195 0.638861306617253 DLL4 other 1 1 1 0.179404096548192 -0.469820197525195 0.451196073124693 24.668372811893 34.5055764929573 0.714909742688343 0.475280222412602 -45.1126258255117 67.3080381367262 -0.67024128282973 0.503274726265604 ALDH1A2 other 1 1 1 0.714909742688343 -0.67024128282973 0.000114902077468941 45.1157002431219 30.7689455311572 1.46627385060814 0.143728819861817 -189.173148913911 60.0688521631427 -3.14927191217389 0.00181923056592416 MINDY2 other 0.844589289122135 1 1 1.46627385060814 -3.14927191217389 9.76540550735226e-15 344.761287509415 70.2044868201343 4.91081557782342 1.5638860407277e-06 -430.182428999232 121.777678972889 -3.53252281228814 0.000483129776722848 IVD other 1.28122120256462e-10 1 0.0171182966018054 4.91081557782342 -3.53252281228814 2.41218036129983e-12 228.498870258057 37.8387699710313 6.0387499496678 5.05993970520068e-09 -68.8155466545583 65.6356565082065 -1.04844760173846 0.295359729856288 KNSTRN other 2.9300754848709e-08 1 6.36287417928986e-05 6.0387499496678 -1.04844760173846 1.00712590282582e-12 380.664182186841 63.8941369822125 5.95773258965551 7.95264407277544e-09 -233.050753479525 120.984369978779 -1.92628811077334 0.0551181049371073 DUT essential 1.24128267523283e-08 1 9.91535662993642e-05 5.95773258965551 -1.92628811077334 0.00225076903232922 64.757404978321 18.8861129140114 3.42883711821283 0.000700507307115385 33.0287469530243 32.7176668076761 1.00950801740163 0.313631550936715 CHAC1 other 1 1 1 3.42883711821283 1.00950801740163 1.27946371749924e-10 312.159456535337 57.2221296919934 5.45522262480585 1.10288334166466e-07 -205.038196841694 110.414955450705 -1.85697848633589 0.0643991446971389 CLN6 other 1.44784114272214e-06 1 0.0013014023431643 5.45522262480585 -1.85697848633589 4.09305937144441e-13 719.530931062387 146.683707587295 4.90532277167984 1.6107258119531e-06 -1029.72868944785 286.461555111969 -3.59464881437705 0.000385803810065811 ARPP19 other 5.11509629649408e-09 1 0.0176084545762713 4.90532277167984 -3.59464881437705 0.000662318570003556 156.052552140505 69.0205862807815 2.26095662974623 0.0245610690078242 -270.398562087938 135.680385825854 -1.99290826335795 0.0472816938245185 VPS13C other 1 1 1 2.26095662974623 -1.99290826335795 0.000407697463491401 28.9504892537961 19.4007631546978 1.49223455917434 0.136800861761632 -104.598449972164 37.4354189710516 -2.79410389537911 0.00557581300577266 CALML4 other 1 1 1 1.49223455917434 -2.79410389537911 0.0828396498483128 -322.139076050518 143.669815178045 -2.24221821160765 0.0257622976463652 -240.673229286679 269.967968688923 -0.891488091922492 0.373464083659617 ISLR other 1 1 1 -2.24221821160765 -0.891488091922492 5.00692591532672e-07 19.0735240171777 4.28204665152879 4.4543008447533 1.23368027033438e-05 -10.0053806924628 8.05450012648947 -1.24221001121563 0.215236950891571 THAP10 other 0.00457382682365096 1 0.12577370356059 4.4543008447533 -1.24221001121563 0.96961273514076 -17.6132631550688 85.1983204190562 -0.206732516186191 0.836374577518379 -33.3950108385445 159.576356926802 -0.209272924145416 0.834392994161097 LOXL1 other 1 1 1 -0.206732516186191 -0.209272924145416 0.0721128628468495 5.18323144191202 3.44442130890145 1.50481923582256 0.133526606844345 -24.7851389841488 16.9166634244717 -1.46513164932362 0.144035702574056 ACKR4 other 1 1 1 1.50481923582256 -1.46513164932362 1.98602237129828e-11 202.305322312196 29.3198428680286 6.89994565191878 3.62614244617782e-11 -197.303665193441 148.089622920869 -1.33232606918629 0.183864127468225 ANAPC13 essential 2.32900843482149e-07 1 4.90907164363553e-07 6.89994565191878 -1.33232606918629 3.23242532301557e-14 168.237403939122 22.2236350102419 7.57020189818583 5.81024227292824e-13 -223.829784939194 98.9007739467649 -2.26317526149669 0.0244132921120012 MBD4 other 4.18405133811136e-10 1 8.2267220342391e-09 7.57020189818583 -2.26317526149669 5.13287087223674e-17 832.151016701018 157.161217202313 5.29488783247202 2.51578144649942e-07 -807.473687689423 255.6423564861 -3.15860680831006 0.00177028084722551 COPB1 essential 7.13212407697295e-13 1 0.00290572757070683 5.29488783247202 -3.15860680831006 1.41973198857503e-18 775.345397121824 141.04237431988 5.4972514526972 9.12040972078568e-08 -783.896730015746 230.101816501015 -3.4067385557223 0.000760356406087175 PSMA1 essential 2.03177844884972e-14 1 0.00108067734781589 5.4972514526972 -3.4067385557223 2.16772821456781e-13 1126.69029922958 147.760044218705 7.62513509783416 5.73628008508286e-13 -542.809567189997 461.080588257248 -1.17725530203226 0.240264659190652 SUMF2 other 2.73480591549874e-09 1 8.12371985649434e-09 7.62513509783416 -1.17725530203226 4.90153076840393e-05 1457.2477965612 465.217041490443 3.1324041610611 0.00192532634892983 -476.191392139868 676.10654669693 -0.704314126917225 0.481846450600532 PALLD other 0.375702333398161 1 1 3.1324041610611 -0.704314126917225 1.55587717084107e-09 342.810284819361 151.003629126065 2.27021222472187 0.0239771864182277 -794.823462789294 222.628572961674 -3.57017723383657 0.000421646373073344 SPCS3 essential 1.66369945878036e-05 1 1 2.27021222472187 -3.57017723383657 0.0391483217772126 39.4031435363218 18.0281092345715 2.18565036541716 0.0297100684395858 -5.30784451537523 34.5677981509435 -0.153548817086874 0.878081483018546 BBOX1 other 1 1 1 2.18565036541716 -0.153548817086874 0.185274349717032 13.6431721837112 9.08713583937244 1.50137209621084 0.134419298020774 -1.11335331401515 17.1480233349768 -0.064926043793295 0.948280575837349 MYOD1 other 1 1 1 1.50137209621084 -0.064926043793295 6.23678924926524e-17 98.5093471583419 16.5397071587723 5.95593055020292 7.96899076240076e-09 -82.7269966501518 31.2115158533712 -2.65052799866548 0.00850753546137249 SERGEF other 8.65105036765581e-13 1 9.93494078348503e-05 5.95593055020292 -2.65052799866548 0.657884749339023 -200.115462712623 333.432890602476 -0.600167135134859 0.548894539380291 -577.883526338306 636.361408910769 -0.908105862873494 0.364626160629494 TPH1 other 1 1 1 -0.600167135134859 -0.908105862873494 7.90295504373525e-07 59.0844513810047 15.4431453661134 3.8259337706328 0.000161525819506045 -36.2943249010715 30.0398227691089 -1.2082070250559 0.228013178949054 E2F8 other 0.00709448274276113 1 1 3.8259337706328 -1.2082070250559 1.60175587588322e-17 374.337544229102 76.2350838344863 4.91030540534099 1.57662365372312e-06 -362.718280650371 114.430127684078 -3.16977956759582 0.00170120971286768 DCTD other 2.24998647885316e-13 1 0.0172545692663459 4.91030540534099 -3.16977956759582 3.67315959851059e-07 292.443072478625 63.9204005023865 4.57511326869278 7.23023583688189e-06 -329.0357607421 186.073603409528 -1.76830971568776 0.0781259271034697 SOX15 other 0.00339032630942527 1 0.0751655317602241 4.57511326869278 -1.76830971568776 9.33882228991897e-11 160.745090532384 22.7238653921646 7.07384451361036 1.26780909384041e-11 164.707503828485 68.0758536218289 2.4194702683195 0.0161968285445259 PIMREG other 1.06415879993627e-06 1 1.73956085765843e-07 7.07384451361036 2.4194702683195 4.56242155445856e-15 268.210445771728 32.3812488753293 8.28289380697953 5.50971793623649e-15 -6.54662229762701 94.6536277431152 -0.0691639871996685 0.944909907215902 RPAIN essential 6.04748977043482e-11 1 8.05961539712674e-11 8.28289380697953 -0.0691639871996685 0.216283027004271 10.2439801996812 6.06613772890994 1.688715399728 0.0924158066289773 17.2400150289821 18.8344973845493 0.915342452574538 0.360819673699432 USP6 other 1 1 1 1.688715399728 0.915342452574538 4.02396267863688e-08 191.407727647996 35.365495507426 5.41227331617069 1.37031833605569e-07 -103.066723455451 105.382444767964 -0.978025549534251 0.328933945114137 PLD2 other 0.000394992176534996 1 0.00160793153552775 5.41227331617069 -0.978025549534251 0.125664357159501 -621.006243738787 408.955285841231 -1.51851868710136 0.130040886228193 -2080.81871995589 1190.47726659676 -1.74788614477651 0.0816079680274279 CD68 other 1 1 1 -1.51851868710136 -1.74788614477651 0.00547641735924734 188.324632915953 88.7784768575181 2.12128704593792 0.0347988083522658 -481.61175843931 265.961379854205 -1.81083343267101 0.0712658118776037 TXNDC17 other 1 1 1 2.12128704593792 -1.81083343267101 0.00879913225367754 -0.427350038655697 19.1558757211404 -0.0223090839007727 0.982217759655697 -168.494057634878 56.4430370072798 -2.98520537817882 0.00309174328184232 ATP1B2 other 1 1 1 -0.0223090839007727 -2.98520537817882 5.68885251420476e-25 406.925890548191 36.0612405962818 11.2843009230844 1.71472579076572e-24 13.273265498685 104.97501468123 0.126442139960551 0.899475020006421 FXR2 other 8.71020208449891e-21 1 2.67480076101545e-20 11.2843009230844 0.126442139960551 0.000588032111810856 541.890089315859 167.281387311695 3.23939260681858 0.00134722462192319 -649.68503115312 530.019692652224 -1.22577526865481 0.221347399121044 KIF1C other 1 1 1 3.23939260681858 -1.22577526865481 7.2577091747268e-17 414.861915523146 49.2062648012116 8.43107919691013 2.00307374016722e-15 -172.177126288159 143.240451091088 -1.20201468912346 0.230399449579036 MPDU1 other 1.00533787488316e-12 1 2.94672177915999e-11 8.43107919691013 -1.20201468912346 3.04496384955607e-08 164.451530832503 27.8968709022388 5.8949812474956 1.12338919115905e-08 -66.7785257498747 117.591393554077 -0.567886166934193 0.57058771382515 PHF20L1 other 0.000301360072190565 1 0.000139199154676518 5.8949812474956 -0.567886166934193 0.0538408938061812 7.66790272277572 3.54353964354677 2.16391052284118 0.0313482059355305 -11.4645841274451 14.9474532091039 -0.766992474708832 0.443756126092438 LRRC6 other 1 1 1 2.16391052284118 -0.766992474708832 1.74129910430283e-11 235.176342381614 42.027665935741 5.59575073098734 5.37219291483463e-08 -278.264950784935 105.424583185208 -2.63946930002166 0.0087846118694775 CCNT1 other 2.04724535692883e-07 1 0.00064450198399271 5.59575073098734 -2.63946930002166 5.47623168412793e-08 66.9207448200528 19.7530411289545 3.38787047438273 0.000812258323353735 -182.910077713428 50.689507409891 -3.60844062331008 0.000368652330027706 PUS7L other 0.000533056392133012 1 1 3.38787047438273 -3.60844062331008 2.92068372804524e-18 307.500966440602 63.7502410817921 4.82352633060753 2.3601038046939e-06 -677.763618281776 130.525178788523 -5.19258908183446 4.08676201875829e-07 KRI1 essential 4.15905362873642e-14 0.00642725062690116 0.0254726003640613 4.82352633060753 -5.19258908183446 2.20679678488207e-06 986.199584886437 319.711999567237 3.08464989184441 0.0022502261481006 -1520.42193881068 655.950188076738 -2.31789237421914 0.0212056209363762 ILF3 essential 0.0190909989860147 1 1 3.08464989184441 -2.31789237421914 0.0221065356028091 453.341400514775 193.817785618148 2.33900825493863 0.0200646066004941 -101.330580843743 397.270844186548 -0.255066744329621 0.798865728960133 SLC44A2 other 1 1 1 2.33900825493863 -0.255066744329621 1.55463215334867e-08 351.780057312957 67.8367624247913 5.18568464559266 4.22685418034831e-07 -81.6215683501374 138.892110738377 -0.58766165994758 0.557250565925854 AP1M2 other 0.00015641154094841 1 0.00480551051763799 5.18568464559266 -0.58766165994758 6.36445428744781e-08 49.268668803836 18.9656523261175 2.59778403382352 0.00989769291884721 -136.275260467528 38.8311497917534 -3.50943150533413 0.000525968621590698 CDKN2D other 0.000616906554082317 1 1 2.59778403382352 -3.50943150533413 3.17091037851122e-09 146.369407084302 155.959416588053 0.938509583367564 0.348818284819434 -1195.24303140419 263.335588329156 -4.53885872011418 8.51158853187887e-06 MTUS1 other 3.32723626017182e-05 0.131121021333594 1 0.938509583367564 -4.53885872011418 0.907328899512873 5.02325455533938 16.3732197428989 0.306796991319804 0.759233497441314 14.9249036287734 36.3785434481145 0.410266663096622 0.681934502504468 KLK14 other 1 1 1 0.306796991319804 0.410266663096622 0.656935641389449 2.27645656414399 6.20297407796172 0.36699437004451 0.713909618752253 -8.74977094950051 13.7868603012787 -0.634645652330938 0.526194954159904 SIGLEC9 other 1 1 1 0.36699437004451 -0.634645652330938 0.74148811204047 131.927094890296 171.807928807962 0.76787547469801 0.443229719968444 78.401796367045 381.728352823318 0.205386358616472 0.837424468371118 KLK10 other 1 1 1 0.76787547469801 0.205386358616472 0.768424148368633 3.39211219652571 43.097757819972 0.0787073937974976 0.937323448938299 -60.9694182794141 95.7559771376149 -0.636716580018733 0.524846925941574 KLK8 other 1 1 1 0.0787073937974976 -0.636716580018733 3.97318983551093e-33 229.818970882536 23.4776369785159 9.78884591719519 1.40177233006971e-19 -166.413541167876 47.6139281228568 -3.49506011641139 0.000553193744793605 NGDN other 6.26254181873232e-29 1 2.14134741141449e-15 9.78884591719519 -3.49506011641139 0.00855994936340502 -3.2128632736034 11.7225177358207 -0.274076213490025 0.784234077697461 -63.6448539376601 22.9730251661823 -2.77041675953715 0.00598422279135656 RIPK3 other 1 1 1 -0.274076213490025 -2.77041675953715 0.809853142974292 -11.1045117452191 19.9480019069071 -0.556672883682357 0.578208658935772 -22.6751850875872 39.0927921927638 -0.580034932674481 0.562371225531116 ADCY4 other 1 1 1 -0.556672883682357 -0.580034932674481 5.64460124718019e-14 82.8849413054201 19.7687057064809 4.19273484749421 3.73570248093764e-05 -166.238558595849 42.2482181816175 -3.93480638357858 0.000105874294375851 RAB2B other 7.25331260262654e-10 1 0.365192021977526 4.19273484749421 -3.93480638357858 1.67436242497289e-16 473.032706768798 62.6597647118793 7.54922571037229 6.63837640039764e-13 -47.805519603898 127.234282020053 -0.375728293074059 0.707411759255167 BCL2L2 other 2.29789499203279e-12 1 9.38600039252223e-09 7.54922571037229 -0.375728293074059 1.25592402442924e-07 469.623920863308 106.681794963393 4.40209991802685 1.54180432149836e-05 -155.647959324848 201.83126365361 -0.771178639558916 0.44127044738476 AJUBA other 0.00119501170924442 1 0.155922671033129 4.40209991802685 -0.771178639558916 6.78504377963969e-15 152.326344027114 25.6564578323124 5.93715410843933 9.06179933877568e-09 -105.568643394912 46.4470847633946 -2.27287985742674 0.0238343595036714 DTD2 other 8.94133069280918e-11 1 0.000112755969172386 5.93715410843933 -2.27287985742674 2.02732073005927e-25 206.746872346253 22.9207006472857 9.02009391107929 3.47907963917332e-17 -116.0309961416 48.8752944194074 -2.37402142575179 0.0182900290359582 PARP2 other 3.11335644515201e-21 1 5.21583619504864e-13 9.02009391107929 -2.37402142575179 4.18886580860062e-08 96.3376597012511 35.9940755350343 2.67648656811542 0.00790367266067798 -211.256987304951 65.1617572574744 -3.24203944455042 0.00133872183472412 HEATR5A other 0.000410843958507549 1 1 2.67648656811542 -3.24203944455042 0.0163976821336872 215.263665594853 137.728741717259 1.56295383890724 0.119284459260771 -311.965156216247 256.90636087134 -1.21431464428583 0.225733611706599 FOXA1 other 1 1 1 1.56295383890724 -1.21431464428583 1.66018022099494e-15 463.207897990018 88.2512598940982 5.24873977488671 3.14205377869283e-07 -519.486222474703 164.402558509979 -3.1598426884772 0.00176162976100326 SNX6 other 2.22381140602273e-11 1 0.00360550671105003 5.24873977488671 -3.1598426884772 8.82873429515549e-21 171.138433881242 26.6680744658235 6.41735248266853 6.35818889975764e-10 -178.298829583947 49.6797403003335 -3.58896460621695 0.000395401552763155 EAPP other 1.30356261867971e-16 1 8.27200375858468e-06 6.41735248266853 -3.58896460621695 0.0364024355796485 446.444187817642 282.474108060566 1.58047826359335 0.115190195216852 -475.832616461091 527.146525015598 -0.902657219350942 0.367527583251892 EGLN3 other 1 1 1 1.58047826359335 -0.902657219350942 1.59981842430453e-07 99.2320647129027 27.9623720752007 3.54877134336217 0.000460018667175419 -99.3038341019711 50.7390352348248 -1.95714864585785 0.0514124662162753 MIS18BP1 essential 0.00151054855622834 1 1 3.54877134336217 -1.95714864585785 6.84718712010875e-15 9.08086784468593 1.92921903326125 4.70701754861664 4.00809193724612e-06 -13.8264136825129 3.83978857268914 -3.60082682178248 0.000376928611164554 NRL other 9.02116903074328e-11 1 0.0425218473622441 4.70701754861664 -3.60082682178248 0.70538658733578 -349.792029962312 470.551078107499 -0.743366759181881 0.457901257826146 -42.8130393194338 1014.04706946219 -0.0422199724339623 0.96635431629705 RNASE1 other 1 1 1 -0.743366759181881 -0.0422199724339623 5.21624612400353e-23 568.087684460171 76.0201482628684 7.47285683389873 1.07621032645064e-12 -453.063385910757 148.979324965595 -3.04111584621146 0.00258706232457117 NEDD8 other 7.87601002263293e-19 1 1.51487365551191e-08 7.47285683389873 -3.04111584621146 1.92681964249493e-13 506.560923175323 112.697306250413 4.49488049030867 1.0309447387244e-05 -684.924465485478 214.131152084184 -3.19862130670369 0.00154424482293228 DAD1 essential 2.43453661829234e-09 1 0.105764620745736 4.49488049030867 -3.19862130670369 5.18807650973303e-13 245.131287066617 39.0227763510742 6.2817490191179 1.32175937970354e-09 -97.8797250518251 83.2107932724691 -1.17628640711696 0.240508891811178 TEP1 other 6.45863644696665e-09 1 1.70136867355439e-05 6.2817490191179 -1.17628640711696 4.05130196782855e-06 -48.7293218302943 29.2760075208952 -1.66447975515496 0.09716386772317 -242.964606312111 48.2688927693638 -5.03356493949495 8.75083156405215e-07 EPB41L4A other 0.0343145276675079 0.0137125530608697 1 -1.66447975515496 -5.03356493949495 0.0640401201729097 -14.0806997084548 13.8467977300632 -1.01689213513128 0.310105092930137 -53.3162771921955 22.6489010849207 -2.35403373401161 0.0192797541982507 CDO1 other 1 1 1 -1.01689213513128 -2.35403373401161 1.61368086123454e-11 310.711575843616 130.973219404804 2.37232907044369 0.0183697081535903 -1087.9776600779 215.9424326762 -5.03827638965841 8.55610428399799e-07 REEP5 other 1.9002705821898e-07 0.0134091266338816 1 2.37232907044369 -5.03827638965841 4.15732736638933e-18 227.037369128652 61.9525599187917 3.66469713965422 0.000300127682520573 -579.481794344142 109.655515475347 -5.28456586822958 2.66869728762204e-07 ITFG1 other 5.90132619658965e-14 0.00420373196746224 1 3.66469713965422 -5.28456586822958 0.0252510758489642 7.37559486625499 8.41339815929458 0.876648736528284 0.381451033682938 -44.0092070586292 19.2872801987971 -2.28177361478753 0.023275428344456 QRICH2 other 1 1 1 0.876648736528284 -2.28177361478753 0.62405547923531 -22.5185204031506 44.1096379529659 -0.510512474102873 0.610108060604618 -93.6879860747144 101.1043246017 -0.926646673560184 0.354934511650426 FOXJ1 other 1 1 1 -0.510512474102873 -0.926646673560184 3.617459545726e-05 458.209089431529 103.317660935885 4.43495415286141 1.3397750848199e-05 -0.432386191799039 229.299153528255 -0.00188568594844707 0.99849682851638 SEC14L1 other 0.28107660670291 1 0.136161341870246 4.43495415286141 -0.00188568594844707 0.0404609872347261 128.329041957132 50.5273953482266 2.53979135620803 0.011650868094808 49.2017166603751 112.447224721449 0.437553854995143 0.662058233934088 RHBDF2 other 1 1 1 2.53979135620803 0.437553854995143 5.86085895599704e-26 384.76628334447 47.0566212814172 8.17666617081186 3.06777119972313e-14 -400.105207079343 99.4485961096149 -4.02323635256084 8.08439611308103e-05 ASH2L other 9.02689496402665e-22 1 4.43722426327953e-10 8.17666617081186 -4.02323635256084 9.8604512353527e-32 173.724168530493 20.4532854647065 8.49370478059701 1.65644790084693e-15 -120.361535613687 37.5398143509081 -3.2062368366714 0.00151579486130867 TTI2 essential 1.54976712066038e-27 1 2.43845695483677e-11 8.49370478059701 -3.2062368366714 0.000428868497105614 0.138863543896063 1.75991354438784 0.0789036167934968 0.937167516736402 -8.00306707849938 2.60889366514679 -3.06760953327283 0.00237623004416749 CHRNA10 other 1 1 1 0.0789036167934968 -3.06760953327283 0.124377417147553 20.8437097929012 49.4940199114392 0.421135923697395 0.673988411279236 -86.4572707892571 71.8456539413763 -1.20337509711866 0.229877509189317 CDKN1C other 1 1 1 0.421135923697395 -1.20337509711866 5.63096019848051e-11 82.8751709635638 12.3559995810409 6.70728178809004 1.15833644703832e-10 -3.29827088200685 31.3455702625946 -0.105222870548403 0.916277090303072 SGO1 other 6.47954590039153e-07 1 1.54522082034912e-06 6.70728178809004 -0.105222870548403 0.274764092582237 -1.76616310616281 2.66371520518718 -0.663045021751379 0.507871593771031 -6.95035061450194 4.39217526091536 -1.5824392702065 0.114728695900544 CDH15 other 1 1 1 -0.663045021751379 -1.5824392702065 3.16173922723352e-06 65.6685324648894 39.4842892410388 1.66315599766794 0.0974415015356735 -222.324190922043 69.8609504738727 -3.18238142215357 0.00163146847737614 KLF16 other 0.0269854443044381 1 1 1.66315599766794 -3.18238142215357 6.16698341368862e-08 218.480184539655 97.3252099820827 2.24484678306758 0.0256093974496519 -590.955247424374 177.546707517396 -3.3284494862653 0.000998118927629447 TMEM8A other 0.000598197391127796 1 1 2.24484678306758 -3.3284494862653 2.35925289937481e-06 47.8621230217975 18.5775337452873 2.57634429187562 0.0105149541132499 -69.806217595483 31.1797387709344 -2.23883266336266 0.0259786321623041 DOHH essential 0.0203532747629064 1 1 2.57634429187562 -2.23883266336266 2.39172206046591e-19 489.315596037202 60.611688393583 8.07295769191948 2.27996070597371e-14 -243.828265514904 139.643507881882 -1.74607662907715 0.0819349856891107 MAU2 essential 3.46464857679092e-15 1 3.3041190550971e-10 8.07295769191948 -1.74607662907715 0.651276683223828 -17.1373730644325 36.9451118118379 -0.463860365390514 0.643121535215705 27.5234029455817 64.990042240309 0.42350184731086 0.672266310556484 SHC2 other 1 1 1 -0.463860365390514 0.42350184731086 0.0341463021597322 17.8692739797154 10.6651741591513 1.67547887292423 0.0950022636888422 48.7787974628158 18.7919765154037 2.59572469254802 0.00995766303839605 PLPPR3 other 1 1 1 1.67547887292423 2.59572469254802 0.526943103769418 -35.5156447880669 189.969210661101 -0.186954742110423 0.851834978558813 197.131033161869 280.084496947679 0.703827006886047 0.482140387494929 INS-IGF2 other 1 1 1 -0.186954742110423 0.703827006886047 1.34269553470979e-08 36.2312421854554 25.2969613207252 1.43223692862162 0.153232702001589 -192.523341862697 44.7588090335892 -4.30135086298248 2.37475059988041e-05 ABHD17A other 0.000135692810737771 0.361888243915775 1 1.43223692862162 -4.30135086298248 0.716211464088366 -2.95650735410582 10.8999019041782 -0.271241647869557 0.786412442297571 -32.418900691316 39.7636594509803 -0.815289667473418 0.415625113335452 LBP other 1 1 1 -0.271241647869557 -0.815289667473418 0.49465605400894 14.3707675114788 13.0129364870812 1.1043447054203 0.270423204377564 25.0647047371509 29.0521593816011 0.862748424580944 0.389038645326579 SYT5 other 1 1 1 1.1043447054203 0.862748424580944 0.280378223990291 5.70740532180267 10.4178164364141 0.547850440314268 0.584245550682666 -26.2061309913597 23.1627517455313 -1.13139109201115 0.258890706613716 TNNI3 other 1 1 1 0.547850440314268 -1.13139109201115 0.0117259181392017 -12.4628599717907 27.4376179924825 -0.454225289352938 0.650032967701109 -120.852656528765 45.2558201846195 -2.67043346106094 0.00803666057436078 CBFA2T3 other 1 1 1 -0.454225289352938 -2.67043346106094 0.000838670592329842 83.9222881052338 42.9143774784951 1.95557510177768 0.0515427163550342 -124.848409160888 74.7203667441008 -1.67087521918173 0.0959007195934741 GAMT other 1 1 1 1.95557510177768 -1.67087521918173 2.286509451372e-13 85.9926246185144 14.201853533172 6.05502826920845 4.68560035456174e-09 -84.7436419125131 26.7713147047832 -3.16546433550281 0.00172571797214915 ERMARD other 2.88191651250927e-09 1 5.89917084639323e-05 6.05502826920845 -3.16546433550281 4.74732727311292e-11 476.300285407481 76.8956098929059 6.19411545172519 2.17644390615918e-09 -228.09938397197 144.952668822478 -1.57361286152876 0.116748002762974 PHF10 other 5.48316300044543e-07 1 2.7769247798685e-05 6.19411545172519 -1.57361286152876 5.35416499729172e-07 36.2958640641562 6.8213265611545 5.32093922476176 2.15961261447683e-07 -14.4483738721002 31.5139569399216 -0.458475395509509 0.646977036434446 CRACR2A other 0.00487710889603303 1 0.0025027750589172 5.32093922476176 -0.458475395509509 0.00010204051510992 531.545081539691 179.814949565 2.95606723926782 0.00338813193783598 -312.414450496129 278.146524946175 -1.12320098392955 0.262338912854469 SH3BP4 other 0.755610014388959 1 1 2.95606723926782 -1.12320098392955 0.000808955003093363 183.311460835818 61.0136054190762 3.00443580700945 0.00290971275564721 -74.2888977912769 118.559232520484 -0.626597323649522 0.531450688848724 DOCK6 other 1 1 1 3.00443580700945 -0.626597323649522 2.40922130893436e-28 301.398240404954 31.8510541069044 9.46273989530599 1.49339463398349e-18 -209.951758484191 67.9092476965764 -3.09165195618527 0.00219725007855525 ECSIT other 3.74874835670187e-24 1 2.26637569653335e-14 9.46273989530599 -3.09165195618527 1.13118671592484e-24 263.342563403585 30.9238928819271 8.51582834053507 1.15611675472319e-15 -196.820033414013 66.0782209568299 -2.97859159287293 0.00315805562556693 ELOF1 other 1.72822706458998e-20 1 1.70504098986576e-11 8.51582834053507 -2.97859159287293 0.00114348855383154 5.34627246218459 1.86071793541111 2.87323100424858 0.00438458336275942 -2.52242206091623 3.61567373119812 -0.697635419687157 0.486003323841729 ANGPTL8 other 1 1 1 2.87323100424858 -0.697635419687157 1.58511762947848e-07 1386.5244706004 310.621283476134 4.46371367436233 1.18105519093102e-05 -640.66058347007 623.378161311644 -1.02772381714827 0.304992812609666 PRKCSH other 0.00149714360104243 1 0.120597545545967 4.46371367436233 -1.02772381714827 0.0296460815702754 -16.4682298746688 35.0070393693588 -0.470426239160436 0.638428900893455 156.36958096078 74.8030945303411 2.09041593723579 0.0375122752146634 CNN1 other 1 1 1 -0.470426239160436 2.09041593723579 9.51123909069375e-31 391.127208765491 40.0312902323991 9.77053715967753 2.08118658234826e-19 -322.546428189689 75.2283169216664 -4.28756672205693 2.54780365603848e-05 CDC16 essential 1.49202807615713e-26 0.38797954074154 3.17505825003051e-15 9.77053715967753 -4.28756672205693 2.38807308786668e-06 207.794955765554 42.5158936032573 4.88746532542912 1.74758896803159e-06 -77.7511706045052 158.989249263197 -0.489034138879372 0.625211620668937 THEM6 other 0.0205875780904986 1 0.0190469721625763 4.88746532542912 -0.489034138879372 0.414183258211037 -1.00054541445697 2.08644584790389 -0.479545354825361 0.631936059241625 -7.79915054599471 5.86459332328507 -1.32987065190498 0.184674993052301 EXOC3L2 other 1 1 1 -0.479545354825361 -1.32987065190498 2.16590092227466e-13 559.304990454697 82.2660921058994 6.79873051140821 6.71287720312127e-11 -416.468143927801 235.346891340524 -1.76959271293375 0.0779195501076637 NECTIN2 other 2.73271719363394e-09 1 9.02340838694338e-07 6.79873051140821 -1.76959271293375 0.134374496043295 -290.763607458683 428.082804916796 -0.679222814182404 0.497576387010718 -2450.86515553859 1218.73258905039 -2.010995010356 0.0453162061710151 APOE other 1 1 1 -0.679222814182404 -2.010995010356 3.61287301061694e-22 553.667691186699 58.2384100946995 9.50691631667826 1.10742834479352e-18 -299.838813632299 165.802147392225 -1.808413330878 0.0716505674775321 TOMM40 essential 5.41678050481797e-18 1 1.68229439857583e-14 9.50691631667826 -1.808413330878 0.799815443190689 -58.0737323220613 133.419815415152 -0.435270669063344 0.663712425012919 -237.549561156559 379.840243999379 -0.625393346042996 0.532239207524401 APOC1 other 1 1 1 -0.435270669063344 -0.625393346042996 0.0158252425123463 28.1225924562002 22.0361351022822 1.2762034869394 0.202976239449213 -76.8240297259337 43.2342982972316 -1.77692324732036 0.0767025357459396 GADD45G other 1 1 1 1.2762034869394 -1.77692324732036 0.570375204691597 -2.74075097824115 4.84115226023936 -0.566136083087303 0.571780377963406 -12.8984751654464 12.199810851364 -1.05726845461742 0.291351922809335 DPP6 other 1 1 1 -0.566136083087303 -1.05726845461742 4.90411230340681e-25 570.01810773708 88.1299743944491 6.46792548907155 4.59454406012281e-10 -582.882855417058 146.485969477843 -3.97910364722831 8.87816541240879e-05 XPO7 other 7.51211922635856e-21 1 6.00644744979855e-06 6.46792548907155 -3.97910364722831 3.49824638197792e-12 60.577714866957 8.98854184765106 6.73943737412621 9.76373928756205e-11 -106.161097896338 47.7068413726051 -2.22528037576806 0.0268979784682056 FAM98C other 4.22268984371462e-08 1 1.30531430535417e-06 6.73943737412621 -2.22528037576806 6.92285416525402e-06 93.805751336786 50.7995235006987 1.84658722902186 0.0658892291473913 -281.661898608317 97.6387881744041 -2.88473365836134 0.00422984427365226 SAFB2 other 0.0574389210091126 1 1 1.84658722902186 -2.88473365836134 1.28063065085131e-12 2385.43115658288 474.318768235673 5.02917302947126 8.93621168686609e-07 -2064.60814540602 911.660317803378 -2.26466821587742 0.0243172982623949 RPL36 essential 1.57120574552947e-08 1 0.00994242912280721 5.02917302947126 -2.26466821587742 0.250160100190908 -10.1373145526697 17.7933929280695 -0.569723525673275 0.569340699114927 -51.2507414962397 31.5307167220966 -1.62542266158902 0.105243508839857 ATP8B3 other 1 1 1 -0.569723525673275 -1.62542266158902 1.08610851250425e-05 25.6251728729115 5.33920484227994 4.7994361763369 2.62791591927585e-06 36.5505862646566 12.3493631425736 2.95971426564102 0.00335054677171336 GDF1 other 0.0886916211310968 1 0.0282816311232467 4.7994361763369 2.95971426564102 0.0109806880054005 84.2850826102473 309.361092040428 0.272448878604401 0.785484366659726 -1203.34729288007 492.720053947998 -2.44225353370145 0.0152352744612825 KIF1A other 1 1 1 0.272448878604401 -2.44225353370145 3.16058691976441e-16 184.139880213148 26.7451272320272 6.88498800606345 3.96596602608901e-11 -130.467783277469 60.4385618984701 -2.15868444217187 0.0317461763026789 GTPBP3 other 4.31104055855865e-12 1 5.36357245368278e-07 6.88498800606345 -2.15868444217187 0.478545215669994 -83.0186619619129 76.23531943557 -1.0889790005022 0.277123507853733 -0.411554642827986 172.276356458638 -0.00238892121523824 0.998095663158047 PLVAP other 1 1 1 -1.0889790005022 -0.00238892121523824 0.644621386589129 113.836455609984 237.2014956434 0.479914577693563 0.631672411134538 -271.692395404159 536.027260311025 -0.506863018956372 0.612660079399289 BST2 other 1 1 1 0.479914577693563 -0.506863018956372 0.492097255700464 21.0671387637731 23.2382443641226 0.906571874951902 0.365432705775282 -15.1508840617935 52.5137180402317 -0.288512880580768 0.773173109210944 SLC27A1 other 1 1 1 0.906571874951902 -0.288512880580768 1.88099975205217e-13 209.869084140408 28.435784870756 7.38045688185812 1.97111037901678e-12 -72.9620318377517 95.6208881130313 -0.763034450710235 0.446111477154225 NSUN5 other 2.37789825081589e-09 1 2.75778053128238e-08 7.38045688185812 -0.763034450710235 0.331940151042308 -4.1689914429035 7.07020945407828 -0.589656002411459 0.555910772610564 15.0994173305793 15.7416268836193 0.959203101573431 0.3383082821405 USHBP1 other 1 1 1 -0.589656002411459 0.959203101573431 1.45549032680472e-16 1206.67285773376 194.829657833088 6.1934762456316 2.1649643827064e-09 -1456.63416595813 446.275142382376 -3.26398230065447 0.00123910592266021 COLGALT1 other 1.99998925806237e-12 1 2.76249455233337e-05 6.1934762456316 -3.26398230065447 8.84304897113961e-18 164.287069932132 32.9786933093929 4.9816124729642 1.12258821372332e-06 -371.312210091474 73.4261535754536 -5.0569475862563 7.84136918697096e-07 DDA1 other 1.24819636227636e-13 0.0122944827482518 0.0123967416441466 4.9816124729642 -5.0569475862563 2.02732046433333e-15 222.816602734336 37.7279959932438 5.90586902029562 1.04387082007254e-08 -265.223999213141 84.0003453716285 -3.15741558013548 0.00177093742160457 MRPL34 essential 2.71052746081366e-11 1 0.0001295130526464 5.90586902029562 -3.15741558013548 1.37379819074745e-13 214.56734745613 36.9212292678261 5.8114898044066 1.72273519013711e-08 -208.408850348376 83.4344881260816 -2.49787414088812 0.0130828203389612 PGLS other 1.74376204351574e-09 1 0.000211517426645034 5.8114898044066 -2.49787414088812 2.68538917378448e-13 217.397389560215 55.5053356648848 3.91669353866731 0.000113685589711725 -336.640445903872 93.149797006373 -3.61396864751987 0.000359379121476309 LSM7 essential 3.37714542495136e-09 1 1 3.91669353866731 -3.61396864751987 3.41747850287752e-10 272.844207819079 56.1074150841032 4.86289035789822 1.95594024411415e-06 -343.242265311211 111.115208264843 -3.08906648037859 0.00221501767143666 TULP4 other 3.78724967688887e-06 1 0.0212512907523002 4.86289035789822 -3.08906648037859 1.46377849371587e-07 93.2943780235895 44.5823927289322 2.0926283295478 0.0373090416194586 -386.954253368983 86.7590621019138 -4.46010184981526 1.19975004714879e-05 SNX9 other 0.00138663736709704 0.184353592244882 1 2.0926283295478 -4.46010184981526 8.42382044416719e-09 37.1440965789799 9.38862313626136 3.9562879497761 9.77916660775602e-05 -48.926423366679 15.997701944439 -3.05834072522437 0.00245358753765043 RTN4IP1 other 8.62430737073837e-05 1 0.918459327800445 3.9562879497761 -3.05834072522437 2.13869052829596e-12 125.638019225227 19.839177548879 6.33282397497001 1.02561567023574e-09 -56.8716139722531 33.8048768859367 -1.68234938894017 0.0936789742064734 QRSL1 essential 2.60364184914751e-08 1 1.32458263810946e-05 6.33282397497001 -1.68234938894017 4.17599156134361e-11 47.1456815281381 11.0335844624006 4.27292523919109 2.6926851484292e-05 -71.1636923140257 18.8006263587833 -3.7851766720942 0.000190000860417167 C6orf203 other 4.83162223647455e-07 1 0.266845098209334 4.27292523919109 -3.7851766720942 5.87605037458913e-13 75.0762732123098 14.4908702316433 5.18093613510993 4.29592885264139e-07 -116.200771150481 28.6977409548147 -4.04912607349276 6.7027296970151e-05 RSPH3 other 7.30569343072667e-09 1 0.00488318232679747 5.18093613510993 -4.04912607349276 5.69956710398114e-17 266.617915492957 69.8219322128285 3.81854106644118 0.000166441366959071 -679.426389275412 129.484306818835 -5.24717169182532 3.11947981339137e-07 MLLT1 other 7.91156909703622e-13 0.00491037317425935 1 3.81854106644118 -5.24717169182532 0.0463880346218281 -2.89788311095199 4.0355233815719 -0.718093500383392 0.473315963534716 -18.3038261693558 7.59888774674714 -2.4087506987047 0.0166723706740347 FUT5 other 1 1 1 -0.718093500383392 -2.4087506987047 1.79996424533534e-09 484.433675752541 113.147351008128 4.2814407181105 2.58266062203989e-05 -742.565296790941 212.914301450913 -3.48762526392404 0.000568749073387521 AFDN other 1.91876188552748e-05 1 0.256406546556121 4.2814407181105 -3.48762526392404 1.05635758341286e-19 3381.28605507362 355.693041968895 9.50619117078291 1.22792279335355e-18 -2290.14168782331 1508.82062865111 -1.51783561566937 0.130243418991248 ACTN4 other 1.53742282689907e-15 1 1.8643551771487e-14 9.50619117078291 -1.51783561566937 0.00879594626831377 31.5667568746295 16.2229915359212 1.94580369500495 0.0527082341155723 -17.5589915346165 24.9688695543202 -0.703235342569942 0.482510585421726 STK33 other 1 1 1 1.94580369500495 -0.703235342569942 2.74340630576404e-20 467.629697681841 70.6587172692458 6.61814586726692 1.91790194535084e-10 -385.096473190201 112.757481898593 -3.415263153327 0.000734085996255218 NDUFA10 other 4.02402836929469e-16 1 2.54160365797893e-06 6.61814586726692 -3.415263153327 6.32807351602044e-06 596.773968168932 145.677877816989 4.09653117626164 5.56563105442365e-05 -1383.15479140159 670.242925950379 -2.06366190204892 0.0400161550178656 ARPC1B other 0.052636915506258 1 0.535580676367188 4.09653117626164 -2.06366190204892 0.889378469786601 -1.55935156076969 3.3679487162429 -0.462997418354165 0.643737794961893 -0.295478275406276 8.5358517714878 -0.0346161441548526 0.972411310885879 CACNG6 other 1 1 1 -0.462997418354165 -0.0346161441548526 0.0229521969635261 19.0983000739098 32.3091817953585 0.591110607346096 0.55494452032623 -115.057047288755 58.2475734667544 -1.97531056558819 0.0492588766944093 ZSWIM6 other 1 1 1 0.591110607346096 -1.97531056558819 1.3003531330918e-06 117.4609608766 23.2982004524195 5.04163234050988 8.41996629812722e-07 36.6559312406283 53.5787542755839 0.684150494654792 0.494460473088969 FCHO1 other 0.0114808178120675 1 0.00938405243926278 5.04163234050988 0.684150494654792 0.0145410828674522 33.0152161732665 15.6375196167732 2.11128215870332 0.035657010580869 99.3661582409852 35.961525128852 2.76312414128575 0.00611432225025056 UNC13A other 1 1 1 2.11128215870332 2.76312414128575 2.2190346017894e-12 231.719844580605 35.1609465433856 6.59026184902849 2.25575031395837e-10 -49.9710624672365 80.8594517328639 -0.617999026660808 0.537091183162476 MAP1S other 2.69967749653698e-08 1 2.98052288983319e-06 6.59026184902849 -0.617999026660808 0.581024645210758 48.9192382394128 126.626076658227 0.38632831033255 0.699565893934802 -187.674135322072 267.214708372101 -0.702334600012857 0.483091647233325 KLHDC7B other 1 1 1 0.38632831033255 -0.702334600012857 0.147237050596902 103.614041238658 61.388814350864 1.68783258537066 0.0926288255531141 -21.4607224801855 129.546729686261 -0.165660086766832 0.868551729084228 SCO2 other 1 1 1 1.68783258537066 -0.165660086766832 0.0248323641112113 1006.97510851628 368.212586049 2.73476558561274 0.00666521062343225 1108.75697641394 1093.37385962279 1.01406940238763 0.311478107027884 PXDN other 1 1 1 2.73476558561274 1.01406940238763 0.0170294652942298 65.4975096607984 26.7316949193276 2.45018169848416 0.0149088082199684 -15.386528553027 61.3247484439043 -0.250902432434787 0.802078974187091 SSBP4 other 1 1 1 2.45018169848416 -0.250902432434787 0.189499148908408 143.738192357234 94.0089195109446 1.52898462300165 0.12743033490988 -46.3887129669391 215.664339948891 -0.215096816552669 0.829853024144429 GDF15 other 1 1 1 1.52898462300165 -0.215096816552669 0.00453503492104801 71.8409188492912 27.4809708666911 2.61420599722579 0.00944195243226892 -41.538160154573 63.0436502616081 -0.658879363460156 0.510530609640649 PGPEP1 other 1 1 1 2.61420599722579 -0.658879363460156 0.672410569395659 13.0051685864274 17.3657609863792 0.748897131351051 0.454563965462365 30.6131266745637 39.7801792119177 0.769557284080621 0.442227882302488 KIAA1683 other 1 1 1 0.748897131351051 0.769557284080621 9.39477878674747e-15 772.673121511374 113.518447396786 6.80658641155136 6.36797786421736e-11 -408.554170244743 260.420831950958 -1.56882292090089 0.117851771209681 LSM4 essential 1.23315866354847e-10 1 8.57002460966373e-07 6.80658641155136 -1.56882292090089 0.0845688899658655 346.577227520087 156.375665044113 2.21631177346116 0.0274946980463668 441.248859158294 358.53662145051 1.2306939731098 0.219496638859112 JUND other 1 1 1 2.21631177346116 1.2306939731098 0.633804952464661 0.188995164492242 2.70710672988889 0.0698144489116612 0.94439283483399 -4.72742045744211 5.61745169859285 -0.84155960942687 0.400776498539054 HRC other 1 1 1 0.0698144489116612 -0.84155960942687 3.67256339916807e-06 103.742072449747 57.5376325679602 1.80302990963719 0.0724901873686173 -433.93569662628 119.418970861034 -3.63372497265317 0.000333910620724254 TRPM4 other 0.0311837358223361 1 1 1.80302990963719 -3.63372497265317 0.717701048545996 5.89540238673912 9.37674608619224 0.628725821574759 0.530054257397296 -5.08633332423059 21.8387367657299 -0.232904191244808 0.816010325374032 SULT4A1 other 1 1 1 0.628725821574759 -0.232904191244808 3.86752598756784e-36 79.5726507635713 7.3884741657517 10.7698354191207 8.95947466541433e-23 -67.2630495441221 16.4618591011905 -4.08599351571766 5.77440178187964e-05 ZNF557 other 6.11842611233233e-32 0.869567164333255 1.3883601941526e-18 10.7698354191207 -4.08599351571766 3.04853255202469e-05 27.1600494756683 21.392065012462 1.26963196212456 0.205300927392981 -125.323664783484 39.6924051018831 -3.15737140296238 0.00177119617134139 CRB3 other 0.238608642846973 1 1 1.26963196212456 -3.15737140296238 2.53301214828208e-06 837.213941549359 248.401990537384 3.37039948729138 0.000858951112719705 -1088.26776167376 464.197066653137 -2.34440895872129 0.0197742306598314 OLFM1 other 0.0218016355602639 1 1 3.37039948729138 -2.34440895872129 2.14914460579952e-10 272.255302037659 52.2353154512166 5.21209261753042 3.68863633849537e-07 -225.495655138578 97.6177731750014 -2.30998564917402 0.0216350253437578 CAMSAP1 other 2.40682704403488e-06 1 0.00421094724402631 5.21209261753042 -2.30998564917402 1.44955005106528e-20 406.568666629443 48.158234790544 8.44234985766701 1.8556507851045e-15 -223.746255935205 89.9984923931819 -2.48611115570371 0.0135131553143914 UBAC1 other 2.1337376751681e-16 1 2.73114682551681e-11 8.44234985766701 -2.48611115570371 0.469658851992573 14.1027872863632 13.9846614751392 1.00844681234752 0.314142892868247 -16.2187944947236 39.1546280204319 -0.414224200680957 0.679038796776047 ZBTB46 other 1 1 1 1.00844681234752 -0.414224200680957 0.0865365578741992 96.2931028176243 70.3111228814435 1.36952872989941 0.17196783907366 -260.742541007031 196.867705890749 -1.3244556278404 0.186467629783967 HELZ2 other 1 1 1 1.36952872989941 -1.3244556278404 0.0106166731653075 21.4077590263758 11.0845803056174 1.93130984089013 0.0544991801278332 -55.5258098815688 31.2130823197103 -1.77892748024138 0.076385069038417 SAMD10 other 1 1 1 1.93130984089013 -1.77892748024138 0.454489365324827 -95.0288505136102 75.6211507460365 -1.2566438036992 0.209956814427774 -98.148243405932 111.49339354309 -0.880305462834441 0.379468130843742 TNNT3 other 1 1 1 -1.2566438036992 -0.880305462834441 0.459801960476418 -39.9265525571069 33.4054879427858 -1.19520938073079 0.23304246498335 -26.3099759220752 49.2519774819635 -0.534191260273967 0.593643944587548 TNNI2 other 1 1 1 -1.19520938073079 -0.534191260273967 0.0343529857610903 -1694.74736632847 796.587744324605 -2.12750871250898 0.0342741176174594 865.930024591728 1495.25155991516 0.579119960684649 0.562985759057373 COL5A1 other 1 1 1 -2.12750871250898 0.579119960684649 1.00418708999321e-18 680.577430279159 93.9639258051671 7.24296504693011 4.55760275108801e-12 -680.38700645559 210.081798407898 -3.23867660888232 0.00135048320288347 ATXN10 other 1.43970303092326e-14 1 6.32139501575907e-08 7.24296504693011 -3.23867660888232 2.29019338658889e-17 448.62706631623 71.5589417689507 6.26933623144898 1.47876163432572e-09 -164.554695835135 99.963804315913 -1.6461427909956 0.100928798921495 TUBGCP2 essential 3.20856093461103e-13 1 1.89932144312795e-05 6.26933623144898 -1.6461427909956 0.215360089143257 19.8415382163493 27.6585195110502 0.717375281363926 0.47378410183507 -32.3085839930385 38.8635795681783 -0.831333200699117 0.406545316652651 CYP2E1 other 1 1 1 0.717375281363926 -0.831333200699117 0.769895805889004 -10.6999154458918 25.9146854010614 -0.412890038227263 0.680018549673539 -34.5190917105353 48.8337494811723 -0.706869574367703 0.480263972360765 PNPLA7 other 1 1 1 -0.412890038227263 -0.706869574367703 4.07515184781565e-46 550.065111763122 31.8862968418624 17.2508308033111 2.05088989053063e-45 -328.496737732466 229.38008521013 -1.43210661654231 0.153274251712468 PAK4 other 6.48356658987471e-42 1 3.26317090482328e-41 17.2508308033111 -1.43210661654231 0.182274538276659 4.7930544093285 3.0059803124426 1.59450625457814 0.112010144248883 -0.851710130385102 7.66790885898759 -0.11107462882619 0.91164093059712 MNX1 other 1 1 1 1.59450625457814 -0.11107462882619 2.76581672477302e-08 154.459386082336 26.9565207858451 5.72994517020323 2.78342011717226e-08 -24.6090127627593 89.6152001524132 -0.274607574617983 0.783836657890503 ZNF337 other 0.000274534968100969 1 0.000338102041632914 5.72994517020323 -0.274607574617983 6.90480532340378e-08 225.733132677734 55.4838334489974 4.06844874706135 6.21167664928556e-05 -92.4753179743959 79.8511637997574 -1.15809605738867 0.24784443103909 CEP85 essential 0.000667832770879614 1 0.595327090067528 4.06844874706135 -1.15809605738867 0.572052704808543 1.44730235226972 3.47630358032489 0.416333705853867 0.677496587574977 10.2643154117002 9.76488313213452 1.05114575083056 0.294131528160065 GATA5 other 1 1 1 0.416333705853867 1.05114575083056 0.495709337714308 3.55627146690356 9.26379436508182 0.383889292740378 0.701362635153782 -25.1210955909923 26.0218554694513 -0.96538448691653 0.335216140634132 RBBP8NL other 1 1 1 0.383889292740378 -0.96538448691653 8.58973745732847e-09 178.865566877188 44.71326406266 4.000279796763 8.17514856305694e-05 -443.672051701379 126.826172289915 -3.49826888007924 0.000547476401915157 OSBPL2 other 8.78816039259276e-05 1 0.7739413144646 4.000279796763 -3.49826888007924 1.95747184801178e-09 566.086440804232 97.1876284307947 5.82467593812447 1.62314671484703e-08 -335.008426779177 275.666184659187 -1.21526848566267 0.225325305605856 ADRM1 essential 2.08255429909973e-05 1 0.000199549657123294 5.82467593812447 -1.21526848566267 0.00340053776269848 694.069917475474 300.221373127347 2.31186044566209 0.0215298676699799 -766.291775228803 573.712891351285 -1.33567118114416 0.182769235115888 ASS1 other 1 1 1 2.31186044566209 -1.33567118114416 8.56512952188951e-15 208.233092853064 33.4994725391518 6.21601109121035 1.90117166594835e-09 -179.841161917614 64.0163591585049 -2.80930006457141 0.0053237671557813 EXOSC2 essential 1.12502976270019e-10 1 2.43178867791454e-05 6.21601109121035 -2.80930006457141 5.78237373479558e-08 108.56143101352 22.9531240083645 4.7297017597238 3.60975597434584e-06 -72.9580769898805 45.9682835153243 -1.58713946683606 0.113638579082623 POMT1 other 0.000561873255810087 1 0.0383933645431424 4.7297017597238 -1.58713946683606 4.10191051698565e-15 130.440749238968 22.5432439719239 5.78624573293107 1.96972993336245e-08 -172.152191069954 45.1474156580553 -3.8131128562004 0.000169692202758298 UCK1 other 5.44323525603995e-11 1 0.000241009001960574 5.78624573293107 -3.8131128562004 0.304715137136653 19.4537531981373 14.9802992676305 1.29862246745451 0.195169381098393 37.3581693029578 29.0938776918033 1.28405603744883 0.200211019939694 FIBCD1 other 1 1 1 1.29862246745451 1.28405603744883 1.44283500471639e-11 1945.41643279612 348.282810114786 5.58573772893055 5.62304157283287e-08 -1685.46045226146 697.506925551226 -2.41640676317224 0.0163308048427034 PRRC2B other 1.70211245506392e-07 1 0.000673977762919748 5.58573772893055 -2.41640676317224 1.46377542758116e-17 445.044234391407 66.5556412441709 6.68679958711065 1.38758219067094e-10 -589.945073898622 161.629622667474 -3.64998113688812 0.000316959134488685 CHMP2A essential 2.0577754960936e-13 1 1.84687189578302e-06 6.68679958711065 -3.64998113688812 2.68448883931918e-22 347.742404393479 42.8134559670478 8.12226895817815 1.87590059490503e-14 -387.064360651515 103.990900258306 -3.72209837293527 0.000242372592330044 UBE2M essential 4.02914929893415e-18 1 2.72211935326668e-10 8.12226895817815 -3.72209837293527 1.99264949398696e-23 2752.33804182351 299.829311055447 9.17968304077688 1.39599874747386e-17 -1897.30962638583 728.132093758241 -2.60572174012122 0.00969664132188365 TRIM28 other 3.01926251328904e-19 1 2.1016761143219e-13 9.17968304077688 -2.60572174012122 1.34373412460283e-09 188.850656120561 44.6117784607334 4.23320169328789 3.16101391508239e-05 -152.258066350558 81.7513864700115 -1.86245240509052 0.0636254329390376 METTL26 other 1.44209546252376e-05 1 0.31117020980071 4.23320169328789 -1.86245240509052 1.9006501984541e-10 425.781786404929 82.2935499399142 5.1739387438725 4.49700596940769e-07 -251.867136050398 157.71133748167 -1.59701350627168 0.111441097087402 YIPF2 other 2.13347984776473e-06 1 0.0051027526734869 5.1739387438725 -1.59701350627168 6.65913330475708e-20 240.327577456399 43.3246493856747 5.54713265690877 6.90064302922147e-08 -440.424730968082 88.6632725458376 -4.96738636328125 1.20312212703591e-06 ATG4D other 9.72300053827581e-16 0.0188072050898254 0.00082228062336203 5.54713265690877 -4.96738636328125 1.93320452796424e-06 15.0292366493581 5.62716522840031 2.67083620959014 0.00802212872376082 -33.5409604949927 11.5639855134121 -2.90046718374832 0.00403042743352415 TMEM160 other 0.0168246790068728 1 1 2.67083620959014 -2.90046718374832 0.0044344318291657 58.762334211448 42.0912332808301 1.39607062162777 0.163831604797789 -181.794623958825 86.4986884416648 -2.10170382041606 0.0364989476060834 ZC3H4 other 1 1 1 1.39607062162777 -2.10170382041606 0.134314678149713 4.13003842743509 4.52001760176275 0.913721757593252 0.361672288758926 -11.1591615984601 9.32099075995444 -1.19720766663593 0.232267961281924 NPAS1 other 1 1 1 0.913721757593252 -1.19720766663593 0.280556538170692 13.2312828639426 11.6053564978955 1.14010137183997 0.255258171027914 -80.7373821895643 87.864077731222 -0.918889542510667 0.358976551975877 GMFG other 1 1 1 1.14010137183997 -0.918889542510667 1.24268788307918e-15 92.3718230009086 11.7324527787704 7.87318941253725 8.43938641744503e-14 -103.800892623538 52.0038221291317 -1.99602429924839 0.0469355907586697 MAP3K10 other 1.66992397728181e-11 1 1.21206467727345e-09 7.87318941253725 -1.99602429924839 1.1122948091586e-05 251.02417514007 76.1708772129809 3.29554003215931 0.00111426460435092 -146.264370201286 119.722868649618 -1.22169115935023 0.222893979344312 ARHGEF16 other 0.0907187646349758 1 1 3.29554003215931 -1.22169115935023 3.53796670809228e-20 396.442770912819 62.9012123416965 6.30262527786005 1.19781043619683e-09 -324.437682246515 98.8941818192621 -3.28065490080552 0.00117287192007599 LRRC47 other 5.18276743068438e-16 1 1.54409743330134e-05 6.30262527786005 -3.28065490080552 1.17831098974882e-06 158.794237198079 32.7704245248118 4.84565700629997 2.12272738053541e-06 37.9351402510578 47.673390483462 0.795729858236485 0.426882945758796 SESN2 other 0.0104398353691746 1 0.0229806466216764 4.84565700629997 0.795729858236485 0.000949700809193945 85.2525670635995 33.8146945952479 2.52116921604788 0.0122706488632732 -45.3360095450438 49.3704877518218 -0.918281580950572 0.35928802049126 SMPDL3B other 1 1 1 2.52116921604788 -0.918281580950572 7.75950883120219e-13 292.615497506446 78.7584774469557 3.71535239115719 0.000246438124851711 -423.212101544308 114.728129298891 -3.68882595864309 0.000272222758324709 ATPIF1 other 9.60394408037895e-09 1 1 3.71535239115719 -3.68882595864309 4.17131203656224e-12 51.1244614669352 19.879415851547 2.57172855825925 0.010650724851509 -130.476417454449 28.9199535317697 -4.51163994129918 9.57982817873172e-06 MED18 essential 5.01683698637341e-08 0.147452715327039 1 2.57172855825925 -4.51163994129918 0.343507502729057 -43.169722367732 82.6328646938543 -0.522428001590785 0.601800741254801 -172.254643994037 120.811372653011 -1.42581480709418 0.155076910294413 THEMIS2 other 1 1 1 -0.522428001590785 -1.42581480709418 2.49727444022938e-06 85.3427095177887 96.252571677894 0.886653811218522 0.376048575753051 -930.298609733986 199.474860424857 -4.66373861725014 4.87346130668056e-06 CLIP1 other 0.0215015329303749 0.0754558014113351 1 0.886653811218522 -4.66373861725014 3.68466428073622e-05 121.237612167558 74.5051226741529 1.62723860878384 0.104844255680936 -566.078122689065 154.532647224029 -3.66316201047414 0.000299375468111488 HIP1R other 0.286003641470745 1 1 1.62723860878384 -3.66316201047414 3.19923837774833e-43 204.173046885223 16.4655516892036 12.4000125072699 2.62091414581543e-28 -238.924811088667 43.5522279944204 -5.48593773708376 9.38188781261145e-08 ZNF317 other 5.0848694775932e-39 0.00148280736878324 4.12296004278225e-24 12.4000125072699 -5.48593773708376 1.16480552635511e-18 235.279760771245 38.191514287465 6.16052453433267 2.58841211146966e-09 -316.964387447434 81.0782912759494 -3.90936195693429 0.000116806357324499 PPAN other 1.66811799429315e-14 1 3.29220136457826e-05 6.16052453433267 -3.90936195693429 6.35727411757463e-38 894.872137586288 75.5387015359041 11.846538521197 2.11432556455062e-26 -522.579818297231 160.364126953332 -3.258707718649 0.0012609413503109 EIF3G essential 1.0073100839297e-33 1 3.31378245732019e-22 11.846538521197 -3.258707718649 9.84561629980804e-05 4.61282730302309 6.77195767959662 0.681165996787189 0.496343835952708 -50.3893745536778 14.3764594700804 -3.50499193897814 0.000533528630640388 ANGPTL6 other 0.730544729445756 1 1 0.681165996787189 -3.50499193897814 0.000429228654692656 17.8693198048084 27.5673094260947 0.648206886229297 0.517395960720827 -186.629589185115 58.5237423821325 -3.18895514176984 0.00159423983427386 C19orf66 other 1 1 1 0.648206886229297 -3.18895514176984 3.65439553891887e-17 829.146018805046 126.507360077847 6.55413264726119 2.78156145567973e-10 -764.446895580419 268.567528161867 -2.84638616147103 0.00475735042668009 DNMT1 other 5.09824721634572e-13 1 3.66220381254793e-06 6.55413264726119 -2.84638616147103 1.24398456725913e-08 66.0912856438836 19.8485725268643 3.32977525484171 0.000989294838247029 -116.480552660578 39.5120001465524 -2.9479791513602 0.00347623327059398 ZNF426 other 0.000125990756972005 1 1 3.32977525484171 -2.9479791513602 0.0262454745810266 88.8416889268942 34.3788395497145 2.58419685162503 0.0102823137729869 16.7549886377767 83.1135785187136 0.201591472012052 0.840386791575676 ZNF331 other 1 1 1 2.58419685162503 0.201591472012052 2.50745684838178e-15 125.262665076772 19.7610065716792 6.33888079650224 1.00125210626986e-09 -51.9922050409894 30.4586130769797 -1.70697874225549 0.0890062630992267 ZNF236 essential 3.34319221594743e-11 1 1.29351759609004e-05 6.33888079650224 -1.70697874225549 0.0145607918209239 4.13088198911431 1.47566916351812 2.79932798708482 0.00549595448186361 -0.661015586343388 5.27593049266605 -0.125288911076871 0.90038946735686 SLC7A10 other 1 1 1 2.79932798708482 -0.125288911076871 4.37797960864935e-10 249.726038562902 40.1687958409879 6.21691622401297 1.94349401331249e-09 -163.504032440657 142.236871354667 -1.14951932563927 0.251370537454226 LRP3 other 4.82409573077071e-06 1 2.48535900172828e-05 6.21691622401297 -1.14951932563927 1.92824145099339e-07 110.54220114728 25.0327665000026 4.41590030200093 1.45281673974784e-05 -119.152402401009 52.0965388171117 -2.28714623094831 0.0229554668585857 C12orf65 other 0.00181293261222399 1 0.147170335736456 4.41590030200093 -2.28714623094831 8.77233289909779e-24 438.745998932316 39.9578704919205 10.9802147494579 2.02533856191533e-23 -26.2111170915071 90.1559146382702 -0.29073097640541 0.771481099285148 NOL11 essential 1.33260509070195e-19 1 3.15061666691549e-19 10.9802147494579 -0.29073097640541 6.5637266376928e-15 499.667650372091 93.9003909226026 5.32125207853439 2.15625168325184e-07 -419.79534469082 150.730094015152 -2.78507983049901 0.00572744480241939 UBE4B other 8.6555863171255e-11 1 0.00249909570088888 5.32125207853439 -2.78507983049901 0.000761892995550573 155.641339474759 75.8263983562155 2.05260097866696 0.0410680388313267 -190.906689944654 118.657403978871 -1.60888982518654 0.108800439413606 CASZ1 other 1 1 1 2.05260097866696 -1.60888982518654 0.00793902761907575 1.81011235553096 1.50287725978684 1.20443126259538 0.229481582559393 -7.19552986687148 3.2909026017759 -2.18649128752352 0.0296413758226909 PKDREJ other 1 1 1 1.20443126259538 -2.18649128752352 0.112239987786444 14.0974688762905 8.84997682022352 1.59293850850272 0.11234397236125 32.5491386838487 17.0678701583978 1.9070416157246 0.0575764213280863 HSD17B3 other 1 1 1 1.59293850850272 1.9070416157246 0.00216763609155119 12.5322342024047 13.909557581101 0.900980072826497 0.368398903445669 -73.349309010759 26.9091169723579 -2.72581627580371 0.00683220094596889 HABP4 other 1 1 1 0.900980072826497 -2.72581627580371 2.03781831398937e-14 113.499795769832 21.7526517829617 5.2177452616942 3.60481039359363e-07 -160.877957721462 42.000394860134 -3.83039155363191 0.00015901927775394 SLC35D2 other 2.65038649917458e-10 1 0.0041195773177988 5.2177452616942 -3.83039155363191 6.26088121484411e-07 19.198345881393 4.53511219537209 4.2332681209043 3.15309511014822e-05 -0.0592664021066256 7.25817635818803 -0.00816546735458784 0.993490957642764 POLN other 0.00566860185191986 1 0.310453744545194 4.2332681209043 -0.00816546735458784 1.00229433567335e-20 196.286045750847 22.8413221962186 8.59346250031628 6.80609187789048e-16 -109.686736804348 41.948909520358 -2.61476968194171 0.00942863310446238 PPIL4 essential 1.47878506285247e-16 1 1.00675711057756e-11 8.59346250031628 -2.61476968194171 0.00260617129978006 58.4990116536364 35.0803610365917 1.66757153931845 0.0965516635774026 -152.266460933274 65.7255318910976 -2.31670184405002 0.0212631167452788 ULBP2 other 1 1 1 1.66757153931845 -2.31670184405002 0.543314235202432 -73.8239055636053 207.567330885578 -0.355662450582366 0.72237107925659 -419.656332334883 379.545343860709 -1.10568167709863 0.269848560330635 AKAP12 other 1 1 1 -0.355662450582366 -1.10568167709863 0.322464905879374 -87.6442778346755 141.746622223183 -0.618316517600525 0.53688412263628 -404.414015759333 269.52328629963 -1.50047894306893 0.134650241678454 SYNE1 other 1 1 1 -0.618316517600525 -1.50047894306893 2.78969648510089e-06 13.103614102375 5.25857620872223 2.49185589069537 0.0133036456887285 -33.7608717116585 9.85231360497193 -3.42669479122357 0.000705458957739668 ULBP3 other 0.0239244370562252 1 1 2.49185589069537 -3.42669479122357 1.36358593528022e-13 169.11370352597 33.229806570381 5.0892172112945 6.73040247502042e-07 -260.400964393765 62.2020759712646 -4.18637095832722 3.83536869651014e-05 LATS1 other 1.73107234483824e-09 0.581096711208252 0.00755218461722041 5.0892172112945 -4.18637095832722 0.0164514888403991 11.6873192495561 75.0964568731374 0.15563076789761 0.876439931739122 -425.792729723463 166.967866840262 -2.55014774867322 0.0113184086154568 EPS8L1 other 1 1 1 0.15563076789761 -2.55014774867322 0.983760315331917 -1.77653597166238 17.1154055294962 -0.103797480497949 0.917406276908056 -7.69195065347487 43.7539241520193 -0.175800246550454 0.860581204788376 LILRB2 other 1 1 1 -0.103797480497949 -0.175800246550454 3.53697951565975e-34 238.324496511388 18.2073221165915 13.0894864706224 1.33331311968017e-30 -201.575101457296 75.6673665201324 -2.66396348554914 0.00819050302152276 AAR2 other 5.58099997775952e-30 1 2.10516808466301e-26 13.0894864706224 -2.66396348554914 0.14669654113816 -2.09987981602607 1.94809072075934 -1.07791685143265 0.282093490059099 -16.0570700533895 8.82688907481431 -1.81910862562043 0.07007225886584 TTLL9 other 1 1 1 -1.07791685143265 -1.81910862562043 1.87261194817157e-17 1091.9898212226 123.557610362849 8.83790013432425 1.34192576388396e-16 -696.680458014725 531.770747919345 -1.31011429406491 0.19128316402589 RBM39 essential 2.62671277970027e-13 1 2.00161646940932e-12 8.83790013432425 -1.31011429406491 0.634213120295337 -8.69271469271475 9.10492638361673 -0.954726521277129 0.340627326585677 -6.27720797720793 41.2275027576757 -0.152257778359841 0.87910497434323 COX4I2 other 1 1 1 -0.954726521277129 -0.152257778359841 0.00219207633171951 15.011405621116 4.68011304467873 3.20748782728314 0.00150096417797082 -17.0807328928698 22.6582963634827 -0.753840121907752 0.451604562687584 ZNF341 other 1 1 1 3.20748782728314 -0.753840121907752 6.73186343845593e-16 228.042148287225 26.6013210547498 8.57258734699218 8.18279454641743e-16 -65.5365215946943 115.745347025972 -0.566213012260343 0.571722802549095 GGT7 other 9.10080618244857e-12 1 1.20859875450585e-11 8.57258734699218 -0.566213012260343 1.32467409285793e-07 251.735989072559 48.0091041627936 5.24350523640163 3.2077403456532e-07 -281.182912928229 211.867076130748 -1.32716662760147 0.18558732930154 ACSS2 other 0.00125817545339646 1 0.00367831585436053 5.24350523640163 -1.32716662760147 0.518364886101932 -0.33149220096329 10.2072026207345 -0.032476302595376 0.974115944673616 22.4646328291085 21.3514492154377 1.05213620876216 0.293667443702833 C1QL1 other 1 1 1 -0.032476302595376 1.05213620876216 0.377236165414262 0.0275727983739175 6.49431437395403 0.00424568272895757 0.996615546244245 -17.6062365290481 13.5848212969626 -1.29602268179889 0.19606227234276 GFAP other 1 1 1 0.00424568272895757 -1.29602268179889 0.400805707918411 14.3346736776987 12.3069691865804 1.16476067018428 0.245132666832467 -5.312147300409 25.7437456026829 -0.206347102026031 0.836673593887086 HIGD1B other 1 1 1 1.16476067018428 -0.206347102026031 1.1968266553616e-15 602.510695009734 86.3394456147604 6.97839429845412 2.47597727740499e-11 -630.749336400637 247.938742132948 -2.54397247874404 0.0115393577956709 ATP6V1E1 essential 1.60877439013707e-11 1 3.36782429272627e-07 6.97839429845412 -2.54397247874404 8.40868369913989e-21 83.8780359487389 9.719552192494 8.62982514909631 5.15984366990673e-16 -78.3030108314378 28.0752941958345 -2.78903616415373 0.00565850538713823 ZNF227 other 1.24187849552597e-16 1 7.64792028753576e-12 8.62982514909631 -2.78903616415373 7.06465098108073e-14 192.377754403831 28.2617760777828 6.80699450290612 6.31382180745884e-11 -141.950737265128 77.8160821972847 -1.82418252444584 0.0692175540052428 ZNF428 other 9.04699204637199e-10 1 8.4984041528396e-07 6.80699450290612 -1.82418252444584 0.887341799477658 6.56224247697745 13.4693659864843 0.487197577344194 0.626513623860232 5.23292066733732 39.6881644360579 0.131850911769128 0.895200414834971 TEX101 other 1 1 1 0.487197577344194 0.131850911769128 1.2094221453332e-60 88.5943610253198 4.20548034467341 21.0664071079376 2.1569973290627e-58 32.5150061912015 11.5147550014116 2.82376882419257 0.00510940304881337 ZNF141 other 1.92806078409018e-56 1 3.43846944225886e-54 21.0664071079376 2.82376882419257 6.24100763114627e-14 1828.90500447037 352.073989108438 5.1946609549366 4.01731644567588e-07 -1263.98271453892 587.998087654627 -2.14963745814315 0.0324626619196298 COX4I1 other 8.00846099228689e-10 1 0.00457572343162483 5.1946609549366 -2.14963745814315 7.13181132731337e-27 206.07428277885 27.0687014527136 7.61300955418352 4.38391951425003e-13 -152.106588448125 45.2073858957738 -3.3646402116417 0.000876343472716046 EMC8 other 1.10321989422211e-22 1 6.22823445389501e-09 7.61300955418352 -3.3646402116417 1.90830121303421e-06 297.856316565497 125.188079306295 2.37927060001247 0.0180344455918327 -502.575946752829 209.076368906609 -2.40379125283796 0.0168928916996944 GSE1 other 0.0166270284691671 1 1 2.37927060001247 -2.40379125283796 2.79501397009042e-12 368.40194971217 57.095163273711 6.45241958493177 4.99596543261476e-10 41.2055537255761 95.3545216568973 0.432130044905905 0.665988016434779 GINS2 essential 3.38532092057352e-08 1 6.52273246882183e-06 6.45241958493177 0.432130044905905 2.56274800271227e-25 548.46586991496 98.3300985580467 5.57780250358629 6.0425744212362e-08 -850.324000431443 160.226243888217 -5.30702074639331 2.36918726626321e-07 CHMP1A essential 3.93176798576116e-21 0.00373383913163082 0.000722752326524062 5.57780250358629 -5.30702074639331 4.68268360536546e-06 111.329799726392 28.2723569387193 3.93776153745163 0.000104649213933426 -51.5210020138917 47.6208526593401 -1.08190003195557 0.280258711249852 F12 other 0.039451609375204 1 0.979307343988998 3.93776153745163 -1.08190003195557 3.64358196647741e-05 25.3266937534127 8.17890385535189 3.09658778258411 0.0021630100051795 -22.8292712999876 13.7762258822226 -1.65714989687033 0.0986463639635088 PRR7 other 0.282960575516636 1 1 3.09658778258411 -1.65714989687033 5.37272765133621e-06 117.731800807731 56.6331096469662 2.07885107389715 0.0386387820003805 -242.670308668686 85.5229679390671 -2.83748698760761 0.00491549564429217 NFATC1 other 0.0450127122628948 1 1 2.07885107389715 -2.83748698760761 0.642142474935078 75.6093636407694 110.860708476972 0.682021292119695 0.496069364897545 -73.9791983715413 278.943506772528 -0.265212118494909 0.791138186378961 IDO1 other 1 1 1 0.682021292119695 -0.265212118494909 1.40422473926042e-05 1.74314805318124 1.25473095560316 1.38926041905398 0.165898237039803 -6.52740601192929 1.98437080093309 -3.28940841543323 0.00113734279877534 GJA9 other 0.113643908148346 1 1 1.38926041905398 -3.28940841543323 3.43079573003397e-09 978.700345100963 291.405261474117 3.35855413231065 0.000896806382007064 -1734.82860026296 498.213087963141 -3.48210161911946 0.000580413548804742 CAP1 essential 3.59101389062656e-05 1 1 3.35855413231065 -3.48210161911946 0.00537805873460088 716.968894277852 291.974872507824 2.45558423613538 0.0146985063582899 -421.096127554814 499.186947084988 -0.843563979414551 0.399662598654858 PPT1 other 1 1 1 2.45558423613538 -0.843563979414551 8.60332263964644e-05 192.752476008233 44.7293954844493 4.30930205786585 2.30747576138183e-05 110.512951531975 99.2244792035608 1.11376701010701 0.266384542197946 TRAF3 other 0.642754234407986 1 0.230055333409768 4.30930205786585 1.11376701010701 4.18028095105198e-22 90.1814947346182 10.9799370883041 8.21329794600376 8.77771818560194e-15 -65.8565941114919 24.1565739525819 -2.72623900395664 0.00682213649164125 HAUS8 essential 6.26331494896117e-18 1 1.27970353427891e-10 8.21329794600376 -2.72623900395664 0.272834603947963 -4.51683747229821 2.93843905726564 -1.53715540267197 0.12541768540414 -1.33114110952156 7.27662222170221 -0.182933931289093 0.854986137816347 ADGRE3 other 1 1 1 -1.53715540267197 -0.182933931289093 7.27263719821033e-14 329.429632879115 45.347605150619 7.26454311721504 3.92713910735621e-12 -142.244470795748 124.04022798888 -1.14676079770266 0.252484567888672 MRPS25 essential 9.31188466858851e-10 1 5.4583306453144e-08 7.26454311721504 -1.14676079770266 0.0119293238601882 -96.0087187782736 97.246511801534 -0.987271594627615 0.324383704498497 -798.04387949076 266.000364405593 -3.00016085043371 0.00294763099365882 SH3BP5 other 1 1 1 -0.987271594627615 -3.00016085043371 3.50752918587247e-13 122.197461135634 17.9790528792018 6.79665730762673 6.71339236295275e-11 -79.5908697301191 49.1784695300469 -1.61840883806868 0.106729227377921 HACL1 other 4.3921280465495e-09 1 9.02340838694338e-07 6.79665730762673 -1.61840883806868 1.5245258340098e-05 214.542349792767 56.539056727675 3.7945866487679 0.000182456428194415 -214.675988097423 151.815526828037 -1.41405818352551 0.158492596405248 TBC1D5 other 0.122998744287911 1 1 3.7945866487679 -1.41405818352551 1.19122940294659e-23 232.526718394428 22.3683585615703 10.3953411581089 1.525247509004e-21 -44.5682319798197 61.1846267625075 -0.728422061849204 0.466979618404483 CAPN7 other 1.80804798779233e-19 1 2.35116903512967e-17 10.3953411581089 -0.728422061849204 0.868547756865282 -33.2649074478449 101.03994845571 -0.329225301044431 0.742238762808883 -137.296066113482 271.34731798003 -0.505979079268386 0.613281159376834 RFTN1 other 1 1 1 -0.329225301044431 -0.505979079268386 3.46931428727968e-12 166.385435801825 23.3636055245481 7.12156501816489 9.47352790872134e-12 -8.65689345543255 63.9069460511 -0.135460916071791 0.892347289322016 RBSN other 4.18850313903276e-08 1 1.30450479303093e-07 7.12156501816489 -0.135460916071791 0.599057619593882 -13.49721407695 14.0719683345162 -0.959156086490303 0.338331919609386 -1.22096857018078 37.7909027531288 -0.0323085314515195 0.974249700502564 GALNT15 other 1 1 1 -0.959156086490303 -0.0323085314515195 0.617597932068997 1.69848929345042 171.794813882872 0.00988673205588403 0.992118878551252 -432.226811614068 469.913853456223 -0.919800104710753 0.358489239463937 SLC6A6 other 1 1 1 0.00988673205588403 -0.919800104710753 2.24065777279838e-05 69.1355440588189 19.9377640625707 3.46756756885329 0.000610956097633046 -70.8720330471998 42.7515513195829 -1.65776517716062 0.0985262292204361 KCNC3 other 0.177997853471103 1 1 3.46756756885329 -1.65776517716062 0.868930525231848 302.946855020283 1172.55490332706 0.258364750478369 0.796322254883334 -832.91218183496 2514.25089429771 -0.331276478303734 0.740692624763826 NAPSA other 1 1 1 0.258364750478369 -0.331276478303734 0.691842317638762 -15.4932147743175 49.5941931091318 -0.3123997751153 0.754977855343882 -91.3332081742319 106.342350386153 -0.858860161004343 0.391179510141664 NAPSB other 1 1 1 -0.3123997751153 -0.858860161004343 3.66923688363761e-15 271.676036492757 64.2320925347118 4.22959965605885 3.20883978553123e-05 -747.223719511958 137.729666764241 -5.42529243747477 1.286751766304e-07 NR1H2 other 4.87311350515911e-11 0.00203190971417064 0.315653569702707 4.22959965605885 -5.42529243747477 0.561281601963184 9.9872106695095 11.8852006015435 0.840306445329366 0.401477343257289 -7.80694457709414 25.4750862789576 -0.306454097607617 0.759494239532207 LRRC4B other 1 1 1 0.840306445329366 -0.306454097607617 0.396001299983717 66.7401531454004 81.3326193250041 0.8205828571524 0.412599842398074 -70.8800026314861 130.313352768953 -0.543919722157383 0.586940638504022 PDLIM4 other 1 1 1 0.8205828571524 -0.543919722157383 2.76699316308817e-06 73.446277922721 23.094207941688 3.18028997176132 0.0016409125370263 -73.7796556911883 37.0021731920239 -1.99392763523122 0.0471546468684537 KIF3A other 0.0237380343461334 1 1 3.18028997176132 -1.99392763523122 5.26285509072176e-08 602.979011071222 192.909115624603 3.12571549104297 0.00196658800317658 -1016.49154577762 316.531841350571 -3.21134057616599 0.00148049964370557 MGAT1 other 0.000512865228590836 1 1 3.12571549104297 -3.21134057616599 0.708718533437394 -22.8276505391111 54.3368548160208 -0.42011357882975 0.674734157008628 -73.890175917478 89.2517435444281 -0.827884957571688 0.408461435031466 GFPT2 other 1 1 1 -0.42011357882975 -0.827884957571688 1.25163639977463e-08 266.658982983186 54.3336631009425 4.90780425549037 1.59826833289741e-06 -137.16659184246 101.737476607491 -1.34824055418296 0.178715165514799 TUBG1 essential 0.000126728185477181 1 0.017478662488566 4.90780425549037 -1.34824055418296 4.74992233739952e-15 701.214289116599 115.223307077498 6.0856983443894 3.99437335864951e-09 -615.432135800357 216.240222586921 -2.84605763182183 0.00476849437999041 PSME3 other 6.29174712811941e-11 1 5.04649130131779e-05 6.0856983443894 -2.84605763182183 1.17149875144713e-05 2605.1898536874 712.233351896392 3.6577757089735 0.000306240445148936 -1709.49948431999 1336.65230112096 -1.27894104015408 0.20202412260077 RPL27 essential 0.0953951433303401 1 1 3.6577757089735 -1.27894104015408 1.96120347037079e-11 109.753299508437 18.8979667216165 5.80767767904339 1.77654490005914e-08 -54.475860481035 35.3873865575355 -1.53941462708652 0.124874211291595 PSMC3IP other 2.30088391143901e-07 1 0.000217964293788256 5.80767767904339 -1.53941462708652 0.836902543359093 33.8714624063689 235.074239949302 0.144088362951525 0.885538982680779 257.503965820871 441.165136293987 0.583690651496254 0.559919370813248 AOC3 other 1 1 1 0.144088362951525 0.583690651496254 3.48409742619399e-16 1405.37656054832 193.911462984505 7.24751667033023 4.46554394008621e-12 -583.001107678216 361.144342473817 -1.61431604793998 0.107626900806245 ACLY other 4.74708274318931e-12 1 6.1950491080816e-08 7.24751667033023 -1.61431604793998 4.31494370700116e-14 308.097225871136 45.3887684420301 6.78796178981225 7.28904904912678e-11 -118.56335351109 85.2533045098806 -1.39071856736473 0.165464449992164 VPS25 essential 5.56714037077289e-10 1 9.7797171092134e-07 6.78796178981225 -1.39071856736473 0.746558188327884 16.21734205856 59.5760329515889 0.272212519953084 0.785668216149177 -58.8942041670912 111.901112390819 -0.526305797223897 0.599111033598446 RAMP2 other 1 1 1 0.272212519953084 -0.526305797223897 6.13050810100703e-08 25.7735828596272 4.8689499966404 5.29345811261382 2.50075379020252e-07 -0.989827607815667 9.1375855956813 -0.108324852057582 0.913819065784293 AOC2 other 0.000594904506121723 1 0.00288862070306293 5.29345811261382 -0.108324852057582 3.02382517817562e-09 218.44862138469 62.8147697855479 3.47766332871205 0.000589358325159292 -325.283409360505 103.209216445357 -3.1516895541274 0.00180615292897119 NDUFA2 other 3.17924979233385e-05 1 1 3.47766332871205 -3.1516895541274 4.40014218284765e-13 546.711869882632 109.387565703086 4.99793432981761 1.04323820462137e-06 -546.68436347738 179.731693415805 -3.04166924089809 0.0025842144761168 ANKHD1 other 5.48917737310244e-09 1 0.0115569928307955 4.99793432981761 -3.04166924089809 1.02253374165772e-07 696.42923633077 174.737955464614 3.98556360854183 8.65305486313234e-05 -588.679017924388 289.667995824512 -2.03225425801277 0.0430994487977061 DIAPH1 other 0.000979382817759763 1 0.81635886953435 3.98556360854183 -2.03225425801277 7.98865907477594e-10 407.494381583622 131.112729943269 3.10796962095091 0.00208268883394424 -844.221627513141 217.7413796837 -3.87717588976193 0.000132453134211247 NDFIP1 other 8.68447128018892e-06 1 1 3.10796962095091 -3.87717588976193 3.79312530060613e-15 435.410985761684 77.9553477453483 5.58538956408754 5.66740011420562e-08 -402.895346442334 128.213734312737 -3.14237276218473 0.00186179645792117 UBE2D2 other 5.0357531490847e-11 1 0.000679237903687544 5.58538956408754 -3.14237276218473 1.97389120115308e-21 329.745255137948 43.8562179660682 7.51878001411508 8.12199862519061e-13 -485.695456492302 118.098819373021 -4.1126190682585 5.19189914475399e-05 EXOC4 essential 2.93596577259508e-17 0.783301823969034 1.14609522600065e-08 7.51878001411508 -4.1126190682585 0.000277769003584607 149.93892508143 86.2879973805658 1.73765679623016 0.0834418747407732 -292.299499767336 135.544477459405 -2.15648402093606 0.0319524918118198 ACAP3 other 1 1 1 1.73765679623016 -2.15648402093606 2.40271868285712e-10 93.5464771786379 22.843208137078 4.09515496322943 5.63185112182334e-05 -84.8131231456564 35.9124673764637 -2.36166237915586 0.0189280833089157 C1orf159 other 2.68431731248797e-06 1 0.541727759408187 4.09515496322943 -2.36166237915586 0.897557449029392 -20.6516948434029 91.1534842969613 -0.226559576989109 0.820965718687947 -132.675555254101 290.530896509168 -0.45666590661525 0.648338455878231 ANO1 other 1 1 1 -0.226559576989109 -0.45666590661525 1.76593557751181e-19 426.596536430924 44.820331304695 9.51792465635427 2.47596887287366e-18 -82.4338405889765 144.966079739524 -0.568642269537081 0.570151336223815 PPFIA1 other 2.56219592941189e-15 1 3.75035005174173e-14 9.51792465635427 -0.568642269537081 0.0591846468745421 -86.201230603357 39.4165690153855 -2.18692881589237 0.0295995187389088 -145.780361815229 72.0744792896704 -2.0226349638869 0.0440891837712031 TMEM204 other 1 1 1 -2.18692881589237 -2.0226349638869 0.862388038142944 -69.096664764858 162.801300803419 -0.42442329652078 0.671593871960034 -152.173341962434 294.777676203956 -0.516230889401357 0.606114114931024 KREMEN2 other 1 1 1 -0.42442329652078 -0.516230889401357 9.24154158321763e-17 225.70555411608 35.1171785956889 6.42721206947383 5.82875863925296e-10 -132.994947438554 63.3294866605244 -2.1000477731877 0.0366490426713269 THOC6 other 1.27616447722652e-12 1 7.59312387935484e-06 6.42721206947383 -2.1000477731877 3.74947384426353e-16 829.867513379976 168.342376780017 4.92964118276893 1.43720106571393e-06 -1053.93661943708 308.147545336228 -3.42023370099249 0.000722084953519094 TRAF7 other 5.10528358634922e-12 1 0.0157603468866189 4.92964118276893 -3.42023370099249 0.0318592431885689 117.826308164413 53.0121170163758 2.22262974572427 0.0270754397076777 -35.4954373181409 101.125907079686 -0.351002412172885 0.725862301780034 BARX1 other 1 1 1 2.22262974572427 -0.351002412172885 0.00018900835820794 235.711248741233 79.2121038020183 2.97569736729082 0.00319006484744859 -225.434046671554 158.586631835919 -1.42151985991353 0.156328298582558 NINJ1 other 1 1 1 2.97569736729082 -1.42151985991353 5.54392824516391e-09 87.1112327787855 23.1839238657418 3.7573981558621 0.000210852544494711 -80.7748724546472 36.4990681144611 -2.21306670628787 0.0277389321850975 NPHP4 other 5.73796573374464e-05 1 1 3.7573981558621 -2.21306670628787 0.325232068004509 669.45461277632 595.196710228072 1.12476195058234 0.26168514314906 -284.777858271204 926.169503565925 -0.307479200270314 0.75871481626131 MAP1B other 1 1 1 1.12476195058234 -0.307479200270314 0.0641885142163924 -1.21892237637026 1.97489994268568 -0.617207155676274 0.537612526892563 -7.07165242707938 3.09951336690241 -2.28153635425249 0.0232868024091782 CKMT2 other 1 1 1 -0.617207155676274 -2.28153635425249 2.05445019230391e-15 130.677720476333 20.949938828335 6.23761823588668 1.68502285076044e-09 -74.7190406775653 32.8799520576759 -2.27248021975512 0.0238352128554162 ZCCHC9 essential 2.74638901707187e-11 1 2.15918828096443e-05 6.23761823588668 -2.27248021975512 0.957624675952813 0.145528998274395 5.02864539220871 0.0289400001240642 0.976933743976559 -2.47151275766925 9.83718920418556 -0.25124176290293 0.801817598204555 KRT34 other 1 1 1 0.0289400001240642 -0.25124176290293 0.599896673084347 -7.91051843210115 7.85408942486173 -1.00718466574378 0.314744479268443 -5.28434189585268 15.3736867554836 -0.34372639301811 0.731318590759878 KRT33B other 1 1 1 -1.00718466574378 -0.34372639301811 0.0819347231396556 624.807567166662 279.116629494971 2.23851788514779 0.0260210210344788 432.521280396219 612.861489196765 0.705740673905118 0.480971699724319 TNS4 other 1 1 1 2.23851788514779 0.705740673905118 9.04296180608471e-12 1544.86397069772 266.089336319695 5.80580940245434 1.82676532388036e-08 -1142.21328495381 590.131129017634 -1.93552454495191 0.0539896845361812 TOP2A essential 1.07394214409062e-07 1 0.000223888358094777 5.80580940245434 -1.93552454495191 2.04906779345234e-08 177.610754735419 43.6486173465455 4.0691038005921 6.23836102839904e-05 -195.593058186782 84.5722178177119 -2.31273417244852 0.0215065093633903 STARD3 other 0.00020484530731143 1 0.597634986520628 4.0691038005921 -2.31273417244852 2.28520756690785e-05 107.895974394553 22.9383971903878 4.70372770595176 4.10209283705763e-06 151.399312275241 101.159273464066 1.49664293831669 0.135667326192079 RARA og 0.181399776661145 1 0.0434698777942998 4.70372770595176 1.49664293831669 0.0244808333890842 192.773278546314 79.7008095524294 2.41871167468509 0.0162523850400635 -9.92882646539899 155.0031694384 -0.0640556351290921 0.948974401825755 PPP1R1B other 1 1 1 2.41871167468509 -0.0640556351290921 1.71281537580528e-05 81.0140015175389 17.0780800582678 4.74374175792194 3.3917192490963e-06 95.7260559764201 69.3635326248616 1.38006315932804 0.168700447825534 KHDRBS3 other 0.137590459138438 1 0.0361523354761174 4.74374175792194 1.38006315932804 2.2912988575658e-08 241.957115969486 39.4627993681361 6.13127096515239 3.33058281616184e-09 -32.3310103704443 133.787885007266 -0.241658729926768 0.809240362083388 CHD1L other 0.000228327931156432 1 4.21951536979543e-05 6.13127096515239 -0.241658729926768 1.40133625067762e-06 114.307071739472 21.6389811452365 5.28246089648429 2.75708619225106e-07 -44.1363815290117 73.2703489129566 -0.602377116853158 0.547464777004301 PEX11B other 0.0123345616784644 1 0.00317588758485399 5.28246089648429 -0.602377116853158 0.324982984771135 1.42215934586427 19.8232506157322 0.0717419848758616 0.942863922941158 100.959712319888 67.2053380984729 1.50225733812925 0.134277753142078 FMO5 other 1 1 1 0.0717419848758616 1.50225733812925 0.105229279882672 121.819544798481 69.5388666337186 1.75181953194809 0.0810212665210828 -275.194997843466 235.461040751715 -1.16874960275764 0.243608940681723 PIAS3 other 1 1 1 1.75181953194809 -1.16874960275764 6.19941144839236e-07 184.922876053248 33.7198250796825 5.48409950574361 1.00605809736276e-07 -34.3017662162833 114.317893116024 -0.30005596920396 0.76438085236937 PRKAB2 other 0.00561604683109864 1 0.00118946248851199 5.48409950574361 -0.30005596920396 2.85947068923373e-05 70.2176369683634 21.0119334070358 3.34179799679221 0.000955153638195236 -52.1432668133252 43.0398188031626 -1.21151222898489 0.226803329522299 CLUHP3 other 0.22449704381174 1 1 3.34179799679221 -1.21151222898489 7.78579957181464e-14 325.193110519642 92.7545108708867 3.50595466965814 0.000532280564585849 -687.437621804569 145.3675343457 -4.72896252178127 3.63394807426829e-06 MCCC2 other 9.95803765235092e-10 0.0563843383203467 1 3.50595466965814 -4.72896252178127 1.34010665940322e-10 62.0121951219513 13.8527114122748 4.4765384390382 1.11690690986e-05 -95.2170731707319 30.8721797131837 -3.08423551739271 0.00225084758046614 ZNF304 other 1.51391849312782e-06 1 0.114237238740481 4.4765384390382 -3.08423551739271 0.00105286639570648 4.85349619162309 3.27536128727143 1.48182010042206 0.139541487270692 -62.2738136638627 19.9939749420476 -3.11462897419662 0.00203783508777959 ZSCAN5A other 1 1 1 1.48182010042206 -3.11462897419662 0.0040253128728996 2.78355455240629 4.0208235406386 0.692284683541273 0.489367017342117 -27.0706933442904 9.79515477968243 -2.76368204006757 0.00611763344731594 ZNF132 other 1 1 1 0.692284683541273 -2.76368204006757 1.73391290027339e-10 294.372316790382 48.487029637044 6.07115591517864 4.28969191847096e-09 -176.596028137268 118.329551180338 -1.49240850130607 0.136759610123002 SELENOS other 1.94926488248734e-06 1 5.40887254000004e-05 6.07115591517864 -1.49240850130607 4.86701273253743e-07 386.371013434834 72.8596621398273 5.30294818953918 2.36765136121437e-07 9.603437787859 177.794615892814 0.0540142216322714 0.95696363042845 CHSY1 other 0.00444942304008572 1 0.0027379520341083 5.30294818953918 0.0540142216322714 5.3213640119888e-11 141.255172101097 22.3532781141666 6.31921507796995 1.08063230254775e-09 -75.3161050872492 54.5517716069326 -1.38063536469415 0.168532932335012 SNRPA1 essential 6.12967920540989e-07 1 1.3949882393589e-05 6.31921507796995 -1.38063536469415 2.17981316906588e-20 396.346634620598 50.7635994090414 7.80769368670902 1.26519859061773e-13 -280.247587321913 125.922755821158 -2.2255515732195 0.0268641406807584 LLGL1 other 3.20214554535778e-16 1 1.81265002077803e-09 7.80769368670902 -2.2255515732195 0.332548830883498 23.7884903677356 30.0930777713486 0.790497088682116 0.429928727197103 -24.7839583525825 43.3771560998197 -0.571359687471201 0.568229390381294 NR0B2 other 1 1 1 0.790497088682116 -0.571359687471201 2.74410107437369e-13 54.7139360613449 8.15646993470112 6.70804116233769 2.76765760213155e-10 -22.6649689298442 20.6999183296191 -1.09493035522818 0.275086967282718 THAP1 essential 3.44933505048773e-09 1 3.64417476472661e-06 6.70804116233769 -1.09493035522818 6.02828166090824e-11 194.501534646848 27.1120407297954 7.17399094318621 7.18367289536365e-12 169.585558593105 97.4136563364666 1.7408807447629 0.0828564191574669 RHPN2 other 6.92649562838356e-07 1 9.91634206475998e-08 7.17399094318621 1.7408807447629 3.95827869143503e-12 94.6407778039898 14.5520381287679 6.50360980135798 4.57376857453076e-10 -126.138734455274 49.1605631663901 -2.5658521044265 0.0109059020984316 C19orf12 other 4.76576754448777e-08 1 5.98020241119897e-06 6.50360980135798 -2.5658521044265 5.92103960046522e-21 58.8183245483211 5.81901489086043 10.1079522310045 1.504961310829e-20 -11.3268535676935 20.9077406767136 -0.541754068162373 0.5884397327018 FAAP24 other 8.76077019284833e-17 1 2.3093631314671e-16 10.1079522310045 -0.541754068162373 3.35776101472625e-17 282.772119386783 41.7871619949118 6.7669615711451 8.05285441467864e-11 -171.20275674567 77.9505280518521 -2.19630015375633 0.0289145774872945 ACTR10 essential 4.68777015265932e-13 1 1.07940460574353e-06 6.7669615711451 -2.19630015375633 0.655656890529806 0.0110159841129882 47.9129355294804 0.000229916701852054 0.999816722794261 -74.8453162104739 91.7218336333433 -0.81600327038453 0.415217569518754 ABHD12B other 1 1 1 0.000229916701852054 -0.81600327038453 0.0271337268836538 79.4026761367126 46.9373581321228 1.69167331303999 0.0918535609881794 -97.5268743738092 89.4591957724481 -1.09018277586445 0.2765974847532 GCH1 other 1 1 1 1.69167331303999 -1.09018277586445 0.0254236140859301 -11.5688767919783 338.321645261219 -0.0341949058064138 0.972746716801438 -1522.60902097936 635.966999021499 -2.39416357031427 0.0173332736330576 LGALS3 other 1 1 1 -0.0341949058064138 -2.39416357031427 0.508910551012849 -19.8535115978275 18.6358626014508 -1.06533901984671 0.287674290440832 -40.8400216826711 47.0774105495026 -0.867507817570536 0.386434174272614 PODNL1 other 1 1 1 -1.06533901984671 -0.867507817570536 7.11440640149729e-13 2386.827410437 351.015735261272 6.7997732599093 6.712846590495e-11 -685.87745020366 866.917039346894 -0.79116849603092 0.429540110141176 DNAJB1 other 8.81759529401574e-09 1 9.02340838694338e-07 6.7997732599093 -0.79116849603092 0.063260195039585 19.9525691563999 18.3636871665952 1.08652303730675 0.278216704561483 -67.6743940977198 46.3898483495544 -1.4588190413511 0.145777252406058 ZSWIM4 other 1 1 1 1.08652303730675 -1.4588190413511 9.1376809421281e-20 101.409483648994 12.2521496805742 8.27687273603739 5.87803707562232e-15 -38.3780514763708 27.3679251096636 -1.40230036886573 0.161974249258021 FBXW9 other 1.33126873645864e-15 1 8.59427800826739e-11 8.27687273603739 -1.40230036886573 0.0299531900582574 26.800937436896 11.4243803714166 2.34594232383499 0.0197054210120496 -5.23860420057329 28.9569528148367 -0.180910064469531 0.856574395604345 RFX1 other 1 1 1 2.34594232383499 -0.180910064469531 3.94708019820113e-09 18.4879480192832 4.58656822678766 4.03088913216314 7.23300318792617e-05 -25.2749248934536 9.97518931875529 -2.53377896757627 0.011849957337216 ZNF20 other 4.11680464672377e-05 1 0.688871223618088 4.03088913216314 -2.53377896757627 4.59513090742691e-05 17.860839791819 7.54295029404096 2.36788512393211 0.0185950061488516 -48.7733651639571 19.0547964074072 -2.55963717067045 0.0110232755585906 C19orf57 other 0.353089858926684 1 1 2.36788512393211 -2.55963717067045 2.09993968764806e-28 262.411024742828 24.291319561283 10.8026665278849 7.8361301115855e-23 -105.891026247284 61.5703059140151 -1.71983920942612 0.0866118352478851 DCAF15 other 3.26813613588668e-24 1 1.2148352511991e-18 10.8026665278849 -1.71983920942612 7.07771211088803e-17 206.613173595173 39.5914781447567 5.21862742380422 3.59785666510967e-07 -479.528419413069 100.014918050387 -4.79456893792068 2.6968662712531e-06 CC2D1A other 9.80687790084645e-13 0.0419578454481557 0.00411199038255384 5.21862742380422 -4.79456893792068 0.441334785550984 61.0815827652681 49.3756816238564 1.23707826922952 0.217132882442284 -9.76848551611362 161.549475662168 -0.0604674541720052 0.951828069054923 MATN3 other 1 1 1 1.23707826922952 -0.0604674541720052 2.90352451513881e-06 40.5912371803773 33.1028746468056 1.22621487147172 0.221174445297734 -159.658815464643 50.2911918365247 -3.17468744792579 0.00167175867724969 TRIM21 other 0.0248628804231337 1 1 1.22621487147172 -3.17468744792579 9.88637737793745e-06 58.9977211248092 14.9636559543646 3.94273440292516 0.000102886378522819 -8.69424818269943 25.6761084192729 -0.338612380066653 0.735166891547248 SPATA6 other 0.0810188626121974 1 0.963736707623243 3.94273440292516 -0.338612380066653 1.77629472695202e-14 485.679612862386 96.1466460780498 5.05144623004448 8.05066398495702e-07 -536.281569985238 168.950478678268 -3.17419384769236 0.00167515371625769 LRRC41 other 2.31291336396423e-10 1 0.00898615114000902 5.05144623004448 -3.17419384769236 0.000423335318517986 10.6916931549961 3.80840642434568 2.80739289973049 0.00535993125721111 -8.86693910306847 7.48207449209474 -1.18509099480858 0.237027367385968 CCT6B other 1 1 1 2.80739289973049 -1.18509099480858 4.92267323792483e-12 496.13115301912 73.7591239063071 6.72636992881495 1.01723741752648e-10 -229.022941244839 184.232843713033 -1.24311678975966 0.21489135185188 DHX30 other 5.9003161429767e-08 1 1.35913091355713e-06 6.72636992881495 -1.24311678975966 4.12756060261226e-31 585.034299850146 50.0778149802583 11.6825045198313 7.6779359570846e-26 -401.621200137955 145.663731811724 -2.75718049471001 0.00622345664324371 RAF1 og 6.48068290216151e-27 1 1.20221121216031e-21 11.6825045198313 -2.75718049471001 3.71982660818146e-13 174.073554359723 21.8582369226338 7.96375091805656 4.52723845377391e-14 185.92474917913 63.6419782084832 2.92141687629609 0.00377571812470877 SLC6A11 other 4.65313110417419e-09 1 6.53054146956887e-10 7.96375091805656 2.92141687629609 0.000580443441407202 36.465997478652 44.3979833458035 0.821343555058087 0.412167282275865 -435.203922956159 129.142534306139 -3.36995030564047 0.000860295931486904 PPARG other 1 1 1 0.821343555058087 -3.36995030564047 0.000711289111929113 1112.99079174545 294.842534343929 3.77486509611659 0.000196436866783751 427.602560589051 805.846921730556 0.530625046839882 0.596110006008723 NUP210 other 1 1 1 3.77486509611659 0.530625046839882 0.5175323276907 -11.275091591202 12.6699063159228 -0.889911204555009 0.374297095588711 -34.7561074728746 44.4015530459466 -0.782767833298738 0.434441928625029 FCRLA other 1 1 1 -0.889911204555009 -0.782767833298738 1.3516612241292e-09 87.9515148478795 13.4554122806026 6.536515791097 3.07989005618517e-10 -34.9124677481823 45.0378308993877 -0.775180932362729 0.438903679157369 HSD17B7 other 1.45033249349063e-05 1 4.05097939090036e-06 6.536515791097 -0.775180932362729 6.16872333598854e-16 544.000723266022 70.1462803748343 7.75523264183211 2.23343124003852e-13 -169.910542325527 153.21832428915 -1.108944005972 0.268519974361279 ENOSF1 other 8.35183452459488e-12 1 3.18933981077501e-09 7.75523264183211 -1.108944005972 0.137537332013513 10.9930687860415 45.7163291733801 0.240462630854504 0.810158961843399 -169.874099120957 98.5852307500729 -1.72311915109892 0.0860423484260666 EMILIN2 other 1 1 1 0.240462630854504 -1.72311915109892 1.17470602063613e-16 210.216605423867 61.9818100483091 3.39158545482978 0.000797703371994528 -435.690823256213 94.0789497293278 -4.63111912398818 5.63325419620095e-06 ARFIP2 other 1.61768766101802e-12 0.0870844766190704 1 3.39158545482978 -4.63111912398818 5.18732885316221e-06 13.2839896358952 32.610202702539 0.407356855676978 0.684066315022775 -183.374959160707 49.4527898141336 -3.70808117903793 0.00025309304045057 TRIM5 other 0.0435113144203246 1 1 0.407356855676978 -3.70808117903793 0.010788775424439 -250.009388499656 149.473407232579 -1.67260112101842 0.0955556209161288 -685.702934983846 226.673751712056 -3.02506545113744 0.00272358464471092 TRIM22 other 1 1 1 -1.67260112101842 -3.02506545113744 6.66331340072384e-26 81.6065365904147 12.9436528373384 6.30475319571346 1.15592811060816e-09 -82.2122788621219 19.6464940867123 -4.18457758922623 3.85571126242562e-05 RRP8 other 1.02601699744346e-21 0.584101699144857 1.49056929862923e-05 6.30475319571346 -4.18457758922623 7.34702056373139e-19 130.383500672807 38.1687535478392 3.41597481063639 0.000732249355271299 -301.710071421179 57.934355957974 -5.20779192988771 3.76721513775421e-07 TIMM10B other 1.05664849747585e-14 0.00592658285471492 1 3.41597481063639 -5.20779192988771 1.00918134625413e-08 323.239593860007 51.4697466578636 6.28018622296099 1.34585868140929e-09 180.106303017129 220.563026226787 0.816575226130335 0.414891092917631 EFR3A other 0.000102785120115984 1 1.73171636536933e-05 6.28018622296099 0.816575226130335 7.22156871969666e-08 315.949239581277 53.9150171083296 5.86013427291418 1.35858622337051e-08 -3.31061952728942 223.135009007609 -0.0148368449308487 0.988173425166333 PTCD3 essential 0.000697747969697091 1 0.000167635954101687 5.86013427291418 -0.0148368449308487 2.25716166768299e-14 588.940219895979 70.2017028267796 8.38925832538805 2.87125020039273e-15 129.237298922466 290.539787108458 0.444817903285041 0.656811727946997 IMMT other 2.93250443865374e-10 1 4.21413391911641e-11 8.38925832538805 0.444817903285041 8.52508588138396e-08 153.122177233525 26.6479728503834 5.74610977327386 2.48545773320648e-08 -53.2025522856454 110.286446725177 -0.482403358394715 0.629914674672464 MRPL35 essential 0.000819687007495068 1 0.000302654188172553 5.74610977327386 -0.482403358394715 0.00464085275322214 25.1572128546263 52.1373613691237 0.482517952462486 0.629824710685651 -212.427123596073 82.4396996212305 -2.57675761280147 0.0104987774819572 IQCA1 other 1 1 1 0.482517952462486 -2.57675761280147 2.81858557949421e-16 98.2516504997601 24.2634151917584 4.04937432439987 6.70231983381507e-05 -190.010176265663 38.7860082673406 -4.89893610489583 1.65641910668195e-06 ILKAP other 3.84877860879934e-12 0.0258335123878118 0.639937497732663 4.04937432439987 -4.89893610489583 0.000591261013885437 77.6708016029779 55.8677317884627 1.39026230556612 0.165581650743099 -217.411065569092 89.2179557846426 -2.43685325063809 0.015454854622265 PER2 other 1 1 1 1.39026230556612 -2.43685325063809 0.00464375977345517 13.0050200861754 41.8329748115445 0.310879638485248 0.756129356870243 -177.099725382045 66.0443921221063 -2.68152555715274 0.00777511597287619 RAMP1 other 1 1 1 0.310879638485248 -2.68152555715274 4.80049870552526e-06 80.8909958849471 28.1716493991695 2.87136172748664 0.00440860625509796 -95.6039926215489 45.0334719109104 -2.12295407315434 0.034660869041432 SCLY other 0.040376994612173 1 1 2.87136172748664 -2.12295407315434 0.248713175014538 -27.0154638495658 75.1094713915614 -0.359681187326276 0.719363634428171 -160.429080475062 104.202318430888 -1.53959223643825 0.124818029428179 PTPRE other 1 1 1 -0.359681187326276 -1.53959223643825 1.14932604937792e-08 1987.33977127593 320.623485240525 6.19835995415329 2.11626062447017e-09 441.081464672563 667.754012827756 0.660544835671902 0.509465338449929 RAN essential 0.000116622114230378 1 2.70077180894883e-05 6.19835995415329 0.660544835671902 2.6191247557371e-24 324.366241906791 29.4119408526594 11.0283861759318 2.1420866418202e-23 -340.070267713213 191.323478260487 -1.77746228954821 0.0766793864091773 PRKAA1 other 3.99468907745023e-20 1 3.33180156268714e-19 11.0283861759318 -1.77746228954821 0.000202103059697477 57.517070302469 16.1057047169704 3.57122344617828 0.000424606310944172 -164.003536717273 104.497558173991 -1.56944850753549 0.117783472637899 CARD6 other 1 1 1 3.57122344617828 -1.56944850753549 7.62705014345814e-12 387.35360423513 52.1498986436758 7.42769620477689 1.4300585183798e-12 150.175965512075 159.649407392418 0.940660964327559 0.347713262426165 RAP1GAP2 other 9.08381672085864e-08 1 2.00808817150892e-08 7.42769620477689 0.940660964327559 6.6874396470194e-17 1007.81461209749 118.245653668304 8.52305840284459 1.08593774373036e-15 -437.410207912524 361.992046501573 -1.20834203994209 0.22796518813745 CLUH other 9.2728038145571e-13 1 1.6020839533254e-11 8.52305840284459 -1.20834203994209 2.08092204808182e-06 154.384497313891 37.8221442614275 4.08185469990231 5.88357440292388e-05 -247.513859126292 117.14534476666 -2.1128783189747 0.0355256071828506 INPP5K other 0.0180540796891579 1 0.564999649912781 4.08185469990231 -2.1128783189747 1.8722536672737e-23 988.953424600292 90.0634197280424 10.9806337310593 1.84110822669757e-23 154.355459550244 269.464135164517 0.572823761707676 0.567237238996773 MYBBP1A essential 2.83777488348675e-19 1 2.86421206827341e-19 10.9806337310593 0.572823761707676 1.45199273627394e-26 1549.55532320426 129.852850903774 11.9331636727217 1.1103580623564e-26 233.897484566289 402.719674881551 0.580794778986359 0.561859672967025 RPA1 essential 2.24158638625971e-22 1 1.74159662080601e-22 11.9331636727217 0.580794778986359 0.670499394548538 -287.971518815009 389.784725915082 -0.738796314142246 0.460667713923478 -821.907808686447 1208.86046784325 -0.679902958653966 0.497144147885284 SERPINF1 other 1 1 1 -0.738796314142246 -0.679902958653966 1.25686421483445e-21 551.543848315677 55.9067368611833 9.86542730413981 8.17484966143454e-20 -216.03468403773 167.05228664212 -1.29321596477482 0.197037668677964 UBE2G1 other 1.87335611221075e-17 1 1.25075199819948e-15 9.86542730413981 -1.29321596477482 8.01709638534131e-19 136.828372143773 14.8796464687017 9.19567359557782 1.02457347472877e-17 -101.850869915201 56.381816839511 -1.80644888058709 0.0719574994054591 EEFSEC essential 1.15133521189887e-14 1 1.54362239702637e-13 9.19567359557782 -1.80644888058709 3.52587414944867e-17 470.336101392256 132.798364339993 3.54173113298364 0.000467836144064985 -865.587781826631 200.248728196815 -4.32256319239085 2.1682737657998e-05 TBC1D14 other 4.92141513780045e-13 0.330813528448075 1 3.54173113298364 -4.32256319239085 4.06968419886723e-17 102.163479673792 25.6102748314044 3.98915983316645 8.53009768350312e-05 -163.568941175732 40.8253400205314 -4.00655428940632 7.95844199188473e-05 TMEM128 other 5.67110493112149e-13 1 0.805411823276365 3.98915983316645 -4.00655428940632 5.07859837371362e-10 76.5238370800726 14.3157619794738 5.34542535631664 1.93152310853923e-07 -46.3202082487026 26.0889857177058 -1.77546987644163 0.076955142636286 COQ3 other 5.57782459384967e-06 1 0.00224481615674429 5.34542535631664 -1.77546987644163 7.09133447216882e-07 462.491986602181 111.791341919911 4.13710023208701 4.71222152096213e-05 -336.609838352404 203.728081459687 -1.65225056821149 0.0996545478370262 PNISR other 0.00639141975976575 1 0.455907432153086 4.13710023208701 -1.65225056821149 0.00589772506048501 38.2603398214312 20.7965686671707 1.83974291306184 0.0669202026637253 -62.5113112217506 35.4939525286494 -1.7611820259041 0.0793565213661195 POPDC3 other 1 1 1 1.83974291306184 -1.7611820259041 4.3025122418534e-14 487.073188689679 61.7698471813951 7.88529049229029 1.129800614309e-13 -226.170498917058 192.117548826717 -1.17725059630578 0.240271447964294 SEC61G essential 5.55153154566344e-10 1 1.61990812079624e-09 7.88529049229029 -1.17725059630578 1.58204004281165e-19 273.809920794166 27.7223255264128 9.87687416531093 1.67604708554095e-19 -48.0965419799505 86.2224122437998 -0.557819489484407 0.577491960209007 LANCL2 other 2.2972803461668e-15 1 2.55898869020393e-15 9.87687416531093 -0.557819489484407 2.31430912323536e-15 192.567703265802 25.3899157653149 7.58441678364561 5.65963155615831e-13 -128.337305622927 66.8897744065555 -1.91863863739312 0.0561043290510718 FIGNL1 other 3.08867695586991e-11 1 8.01630213614263e-09 7.58441678364561 -1.91863863739312 0.563262966853089 88.5331448071035 116.037310459823 0.762971362023744 0.446161690629743 -150.454145470631 305.67962738406 -0.492195527579593 0.622990166234099 DDC other 1 1 1 0.762971362023744 -0.492195527579593 9.44314483012797e-41 939.527610800223 78.6683354014542 11.9428942535227 1.11319063107837e-26 -409.284988900989 147.360923587168 -2.77743229981104 0.00586296111982821 GRSF1 essential 1.49891037888621e-36 1 1.74592818578331e-22 11.9428942535227 -2.77743229981104 0.0615978662056065 -166.464570092591 97.5787683910831 -1.70595071896606 0.089167207661738 -422.56685657374 182.783801884571 -2.31183973753097 0.021539343918197 ENAM other 1 1 1 -1.70595071896606 -2.31183973753097 0.0457717047711331 -2269.76044024681 1227.72288041231 -1.84875632478605 0.0655861824769681 -5552.676288625 2299.76110010982 -2.41445787058484 0.0164239067244777 JCHAIN other 1 1 1 -1.84875632478605 -2.41445787058484 2.61727540192211e-33 957.485068455889 84.7852291864732 11.2930645779117 1.83120377131998e-24 -346.753244885039 183.2378351338 -1.8923670683614 0.0595157666916338 ANKRD17 other 4.1261346711302e-29 1 2.8563116425049e-20 11.2930645779117 -1.8923670683614 4.389414138358e-33 281.495903915462 25.7223806205981 10.9436178582181 2.59792749277931e-23 -73.4190734222945 48.1829664472849 -1.52375577586364 0.12874011933297 UTP3 essential 6.91727774063837e-29 1 4.03899787302399e-19 10.9436178582181 -1.52375577586364 0.00361838190727963 2626.85653693153 836.873380546153 3.13889364627324 0.00188324788801083 3884.63693599727 1943.28072190951 1.99900966041599 0.0466058573896291 ITGB4 other 1 1 1 3.13889364627324 1.99900966041599 7.09411328973562e-09 467.689287314049 73.8998308919703 6.32869225367695 1.01950415606341e-09 174.410260037249 172.554879803985 1.01075240662781 0.313036537652908 WBP2 other 7.29132963919027e-05 1 1.31679156797151e-05 6.32869225367695 1.01075240662781 5.42767736359877e-15 194.441745616369 24.1072945233293 8.06568092608662 2.36550749250332e-14 -63.3949112945501 56.2901329903358 -1.12621711704668 0.261069946254581 UNK other 7.17538947467757e-11 1 3.42762035663731e-10 8.06568092608662 -1.12621711704668 0.0696194679580657 59.7122032159166 60.1802101368752 0.992223242160603 0.321973734040562 318.721645746258 140.519792825065 2.26816193888813 0.0241064506631686 TRIM47 other 1 1 1 0.992223242160603 2.26816193888813 3.53696387726782e-10 288.074960567486 80.0168790099227 3.60017741421484 0.000378061290291058 -347.685600020685 125.515322121446 -2.77006499401143 0.00599195554212859 ZRANB2 other 3.91612640491093e-06 1 1 3.60017741421484 -2.77006499401143 3.25121942186886e-17 3190.30769969545 367.974307300603 8.66991971015314 4.02873988786359e-16 -1175.84291001477 1100.94434363111 -1.06803120141081 0.286456897318268 EIF5A essential 4.54032792263986e-13 1 5.97905286757836e-12 8.66991971015314 -1.06803120141081 0.0151058807726094 352.512164818035 121.422312858475 2.90319099117236 0.00399546518269143 190.998184313372 358.230801870287 0.533170747228294 0.594349156817061 KDM6B other 1 1 1 2.90319099117236 0.533170747228294 0.00170991114646643 -48.1685658949642 13.5857834650504 -3.54551255868891 0.000460933264459827 -65.8276183500897 40.7001093583107 -1.61738185444576 0.106950710183655 CLEC10A other 1 1 1 -3.54551255868891 -1.61738185444576 2.29470431306682e-08 120.875744609447 19.9969476633799 6.04470975491951 4.89772695412021e-09 41.2358018071262 62.0876866461416 0.664154263664916 0.507152121895095 SLC52A1 other 0.000228644337753978 1 6.16183028097863e-05 6.04470975491951 0.664154263664916 2.44008446239126e-06 13.8030361217159 2.65132388831165 5.206092014094 3.79872050699918e-07 12.0608513866614 7.82216925512499 1.54188064631294 0.12426091363805 GUCY2D other 0.0210213276435007 1 0.00433434009848607 5.206092014094 1.54188064631294 1.59545679202647e-28 633.086599048704 54.4020251629036 11.6371880854245 1.17810840049225e-25 -322.872782646921 162.765716782091 -1.98366578067039 0.0483021097933926 GPS2 other 2.4838071338268e-24 1 1.84362183593033e-21 11.6371880854245 -1.98366578067039 0.00986428925566063 50.7746148995577 104.615305486053 0.485345950706292 0.627820223694211 -872.600705772695 313.40514036521 -2.7842577972903 0.00574017029891218 XAF1 other 1 1 1 0.485345950706292 -2.7842577972903 0.0109371131033259 11.618697690188 28.5495752657158 0.406965693256406 0.684353246331856 -237.736043160647 85.4185487462127 -2.78318991191228 0.00575997027869603 DLG4 other 1 1 1 0.406965693256406 -2.78318991191228 5.70780700676897e-11 89.0984433759303 12.8931449499501 6.91052832507518 3.47015459525585e-11 -0.0126142810507549 47.4642633382249 -0.000265763759164805 0.999788147452407 RIDA other 6.5668319612877e-07 1 4.699630368355e-07 6.91052832507518 -0.000265763759164805 5.81114636644665e-11 179.726920228293 29.2815524821569 6.1378890459381 2.9976774647404e-09 -230.020877445214 114.552503323641 -2.00799520544169 0.0456472486529862 VPS13B other 6.68339943605029e-07 1 3.80435247050205e-05 6.1378890459381 -2.00799520544169 0.568019646852445 1.86257031588056 4.79866764142893 0.388143221214198 0.698217036588899 -16.1198326842637 18.7871507246595 -0.858024344431605 0.391642862906554 RGS22 other 1 1 1 0.388143221214198 -0.858024344431605 0.923703097878347 34.0880573129889 88.3403519779391 0.385871875646382 0.699895425195676 2.98549552256862 321.532264399976 0.00928521287946007 0.992598435305948 MATN2 other 1 1 1 0.385871875646382 0.00928521287946007 0.116222145516612 45.1744469455868 32.0426555616712 1.40982219337724 0.159734586237148 -36.1449118994028 53.1180062898473 -0.680464392849612 0.496789258569386 REEP2 other 1 1 1 1.40982219337724 -0.680464392849612 9.90963467071383e-11 24.5524904439869 10.4649618805227 2.346161479067 0.0196833736412813 -79.3664930482632 17.0224250214309 -4.66246688990212 4.89374906909174e-06 PCBD2 other 1.12791461822065e-06 0.0757601293386092 1 2.346161479067 -4.66246688990212 8.89129701196943e-18 229.096296665759 32.7993727487553 6.98477676450239 2.43626479618575e-11 -216.799441372413 74.1110539103063 -2.92533205147503 0.00374836941463468 SDF2 other 1.25491766026937e-13 1 3.31478188169034e-07 6.98477676450239 -2.92533205147503 1.03151962052741e-12 858.316765952171 155.003522814826 5.53740166910628 7.47947065374103e-08 -926.31807125317 350.215941371582 -2.64499116637966 0.00866465460440041 FLOT2 other 1.27072902052772e-08 1 0.00089013180250172 5.53740166910628 -2.64499116637966 2.80497094325802e-32 496.464439262833 41.448868744598 11.9777560715101 1.22661494636395e-26 -123.853751287873 93.6498366138299 -1.32251967292362 0.187152848008866 ERAL1 essential 4.41418277340514e-28 1 1.92345489739331e-22 11.9777560715101 -1.32251967292362 1.2096936261188e-16 112.194258857961 23.4574304397821 4.78288784212645 2.84048713509969e-06 -173.455003873986 42.2688099662649 -4.10361692255879 5.38583469010249e-05 PRMT7 other 1.66526424571514e-12 0.812076154573654 0.0304755864724846 4.78288784212645 -4.10361692255879 6.55803227149575e-18 299.714807835075 42.4833920140603 7.05487000039641 1.45316415024869e-11 -146.493342560028 77.0013527495758 -1.90247751927754 0.058172642899908 NIP7 essential 9.27895986093933e-14 1 1.99010830376558e-07 7.05487000039641 -1.90247751927754 1.97174299006644e-22 123.723846690359 21.337922767591 5.79830792518736 1.86053297091421e-08 -192.845319782568 38.5580184335715 -5.00143232502483 1.02395859914249e-06 TERF2 essential 2.96274101687383e-18 0.0160321197867739 0.000227878078277572 5.79830792518736 -5.00143232502483 1.92714073755976e-23 326.434201882083 52.5795720438963 6.20838453400796 2.01946689145701e-09 -464.236885306559 95.5940186257919 -4.85633821006982 2.03130255621505e-06 VPS4A other 2.92077450184558e-19 0.0316436312207181 2.57946506045804e-05 6.20838453400796 -4.85633821006982 0.000111829609420955 41.6414839935862 114.309319506524 0.364287742883549 0.715927226106946 -681.594547315278 197.431647223371 -3.45230644074065 0.000644669789074812 MTSS1L other 0.82403256581487 1 1 0.364287742883549 -3.45230644074065 0.51421270600977 6.55506788530642 15.7857216673454 0.415252975026561 0.678285298665158 -54.6163813121511 57.0717776491077 -0.956977048234715 0.339431763377232 HSPA12B other 1 1 1 0.415252975026561 -0.956977048234715 1.59984986299906e-12 122.778304890551 18.3908202954301 6.67606462997523 1.45897084554961e-10 -116.670027945868 65.6770172087085 -1.77642092933536 0.0768239753187447 ANKEF1 other 1.95773627735195e-08 1 1.9407230187501e-06 6.67606462997523 -1.77642092933536 1.7591008243554e-09 183.392049177771 31.1355601913655 5.89011561220051 1.13603880213241e-08 -184.02028270977 111.053010382248 -1.65704902619358 0.0986625204382272 PCED1A other 1.8759051190926e-05 1 0.000140743847196185 5.89011561220051 -1.65704902619358 0.894136525149427 -5.30175438767703 37.4857716250279 -0.141433780280976 0.887635956964848 -63.3422893165972 133.868616437432 -0.473167580290951 0.63648759920322 SNAP25 other 1 1 1 -0.141433780280976 -0.473167580290951 0.000955722796840009 142.406401548239 50.3410583007825 2.82883209759667 0.00503164988600751 -272.121272478086 177.309538123928 -1.53472438853171 0.126053627756627 BTBD3 other 1 1 1 2.82883209759667 -1.53472438853171 2.06587620978214e-10 782.999767373332 125.671580189569 6.2305237683191 1.76104814362651e-09 -664.157233067952 453.730305671005 -1.46377093345298 0.1444112353202 PCNA essential 2.31543405592382e-06 1 2.25420765553935e-05 6.2305237683191 -1.46377093345298 4.64489601152414e-08 100.754410855406 23.3430366680664 4.31625123535187 2.2434625073486e-05 -198.953058164846 75.0852859174981 -2.64969435401033 0.00854062598256288 NXT1 other 0.00045417793200683 1 0.223785385108022 4.31625123535187 -2.64969435401033 2.63535061108679e-17 78.2277323132404 9.6745787503406 8.08590578793793 2.09314477437707e-14 -78.6404508654491 32.6557027775611 -2.40816899275204 0.0167033557875709 POLR3F other 3.68685550491043e-13 1 3.03464129389188e-10 8.08590578793793 -2.40816899275204 0.00125869450835466 146.105470996118 80.1432531296322 1.82305391022488 0.0693968980962964 -683.729173474464 262.866582547841 -2.60105018617201 0.00980436791099448 RIN2 other 1 1 1 1.82305391022488 -2.60105018617201 2.41347236172909e-25 528.441320560428 48.6724509670374 10.8570928741252 4.73934722019332e-23 -413.955814896872 173.602856969661 -2.38449886207354 0.017788028013112 PTPRA other 3.70371468630946e-21 1 7.36068016768224e-19 10.8570928741252 -2.38449886207354 8.72340287791466e-17 684.68525510415 74.9606379300239 9.13393047352809 1.64101948797396e-17 -145.889611640012 240.532334814581 -0.606528065145477 0.544675673565114 DAP3 essential 1.20592321384292e-12 1 2.46907792160563e-13 9.13393047352809 -0.606528065145477 0.556030688440043 53.1495855991609 103.338538896839 0.514324918530341 0.607442466135828 331.598891109219 336.431669516896 0.985635185847347 0.325188096119232 NES other 1 1 1 0.514324918530341 0.985635185847347 0.257197589896274 90.8691637866078 55.2751240252327 1.64394319124688 0.101343235205807 -10.6669263496692 179.955149909048 -0.0592754714441926 0.952776223375608 BCAN other 1 1 1 1.64394319124688 -0.0592754714441926 8.50314997542746e-06 300.111286216511 61.004050902389 4.91953045375152 1.50414058527579e-06 -15.8322359420188 196.144475873899 -0.0807172155702072 0.935726203752659 ARHGEF11 other 0.0700574526475469 1 0.0164718435493552 4.91953045375152 -0.0807172155702072 0.0561747302532212 225.533055174245 93.8580173572784 2.40291731622388 0.0169374160610177 -0.87909687717923 308.94208445575 -0.00284550704293945 0.99773171041673 RAB25 other 1 1 1 2.40291731622388 -0.00284550704293945 0.844226609944034 -3.85015148872303 7.21326011313487 -0.533760245483476 0.593946567701771 -6.33886275722671 23.4503059966121 -0.270310449601063 0.787127929913929 FCRL2 other 1 1 1 -0.533760245483476 -0.270310449601063 5.45358885046449e-17 624.654245195143 67.311317887021 9.28007747885128 5.52535103898105e-18 233.463404694632 251.696973444187 0.927557457286634 0.354459503358219 DCAF8 other 7.57394419552509e-13 1 8.34659527948477e-14 9.28007747885128 0.927557457286634 0.462196957894596 63.7293906810033 57.9803923557046 1.09915418112436 0.272679933587983 -92.045665737422 190.223285066262 -0.483882221387141 0.628861680258415 SYT11 other 1 1 1 1.09915418112436 -0.483882221387141 7.4996832926419e-46 210.514839958845 12.0017829058112 17.5402972717424 1.29695824925155e-45 17.7902386465741 55.384590694684 0.321212785423395 0.748314335186378 IGHMBP2 other 1.1931246150264e-41 1 2.06371996620906e-41 17.5402972717424 0.321212785423395 0.176496642962035 7.66942353958515 4.65022947866259 1.6492570043642 0.100266604136581 -4.57867789963956 13.5353763158937 -0.338274887434281 0.735420894533177 ACY3 other 1 1 1 1.6492570043642 -0.338274887434281 0.082002623242334 -68.4602505158437 125.287355835241 -0.546425854863376 0.58522785987929 -817.860024486511 364.672650378747 -2.24272377881118 0.0257322824150441 ALDH3B2 other 1 1 1 -0.546425854863376 -2.24272377881118 8.02852111724854e-30 167.406800130108 12.8336565312841 13.0443572119938 3.28070607655882e-30 35.3661682483307 55.394336496206 0.638443755901886 0.523751165592728 TESMIN other 1.25686498090526e-25 1 5.17596997698685e-26 13.0443572119938 0.638443755901886 0.183113137989789 -48.428620027252 522.555337796066 -0.0926765387786583 0.92622875874236 -1474.66429943556 906.25040825335 -1.62721504564917 0.104849261485211 MMACHC other 1 1 1 -0.0926765387786583 -1.62721504564917 2.25930703421546e-23 262.997870581027 32.7610754943974 8.02775448034371 3.03736564272976e-14 -190.627665165647 61.0627636544578 -3.12183160009547 0.00199179199840621 DPH2 other 3.42149457261589e-19 1 4.39354940220859e-10 8.02775448034371 -3.12183160009547 2.50617364736061e-30 104.527313704723 11.9804196059839 8.72484580193785 2.7202348061688e-16 -85.0876432959119 20.7333798820059 -4.1038964114943 5.37437200827357e-05 TOE1 essential 3.92892842696723e-26 0.810401555127571 4.04580522721486e-12 8.72484580193785 -4.1038964114943 3.55524126245706e-19 1578.46041168023 193.050166599641 8.17642605278729 1.1223730894841e-14 -240.150598372428 334.535606931858 -0.717862593387092 0.47345810965441 NASP essential 5.13696810012421e-15 1 1.63462416752464e-10 8.17642605278729 -0.717862593387092 9.74322395413903e-19 144.61747256937 20.2892409902177 7.12779115981204 9.18511645076299e-12 -75.3364295700065 35.1126717429527 -2.14556243744474 0.0327931635201875 MUTYH ts 1.397080882784e-14 1 1.26515793992809e-07 7.12779115981204 -2.14556243744474 3.77915444507858e-28 351.771848631234 29.3705664862555 11.9770195374288 8.85980502923122e-27 -104.125299550753 106.75497700359 -0.975367167633332 0.330254459614405 CTNNBL1 essential 5.87734099298621e-24 1 1.39001481103609e-22 11.9770195374288 -0.975367167633332 3.94702135055942e-06 239.771309416211 49.6591893857151 4.82833715938954 2.32096397014074e-06 -53.6161114392736 172.204927467345 -0.311350622934067 0.755777044612581 LPIN3 other 0.0334549529673417 1 0.0250640899135498 4.82833715938954 -0.311350622934067 3.48083561635951e-09 18.4389478632572 3.4308104379887 5.37451666203596 1.66115656663297e-07 -21.6583843122802 11.3741153222134 -1.90418188129163 0.0579493962699005 ZSWIM3 other 3.64130213827368e-05 1 0.00193923417588732 5.37451666203596 -1.90418188129163 1.51682665178318e-07 479.565310867702 95.9527559743482 4.99793159662769 1.04540543174709e-06 -389.431492320369 299.129140900191 -1.30188416664597 0.194069704639566 RBM38 other 0.00143506969525206 1 0.0115789105620308 4.99793159662769 -1.30188416664597 0.198470442000268 -74.8621864991921 42.2253761697122 -1.77291935063659 0.0773736693688317 -20.9408466300145 153.479132384971 -0.136441002138902 0.891574716976908 VSTM2L other 1 1 1 -1.77291935063659 -0.136441002138902 6.37354410973387e-06 180.224574690476 48.2129505709882 3.73809469356403 0.000226023522184171 -370.614282094416 166.222344291654 -2.2296297388523 0.0265885448994418 OSER1 other 0.0529896457283274 1 1 3.73809469356403 -2.2296297388523 4.19080915448408e-15 652.814394712577 96.6524209473617 6.75424772927425 8.68111899294414e-11 -1154.09167047926 333.225654125422 -3.46339381794677 0.00061943209286932 SERINC3 other 5.55952742433858e-11 1 1.16231502196529e-06 6.75424772927425 -3.46339381794677 5.41058459346462e-06 148.704458900422 32.344871394924 4.59746638299382 6.56618410953041e-06 -71.4916242345991 96.1022935955227 -0.743911737793632 0.457574380785692 PPP1R3D other 0.0453152583974693 1 0.0684656017100736 4.59746638299382 -0.743911737793632 7.80116824316438e-05 6.3076066996828 4.0812156526449 1.54552153978804 0.123382813170396 -18.1609057016102 6.40199676695635 -2.83675646250666 0.00490017631243469 DMGDH other 0.585477676649486 1 1 1.54552153978804 -2.83675646250666 0.0445219503077126 35.3817817595011 27.3602047379594 1.29318410071737 0.19704462577452 -52.6532514505695 42.9185706376885 -1.22681745147246 0.220952073118111 BHMT2 other 1 1 1 1.29318410071737 -1.22681745147246 4.3644952433715e-16 313.160282044918 47.5888520661369 6.58053868602885 2.39978237618759e-10 -157.086621661236 75.1676207947794 -2.08981766351378 0.0375630271921765 AP3B1 other 5.9317854852662e-12 1 3.16747275833e-06 6.58053868602885 -2.08981766351378 0.37412663032835 21.6490397996106 31.9025147712437 0.678599789228046 0.497970547636324 -36.9602189442433 50.3641181577701 -0.733860142819578 0.463668399033036 ZBED3 other 1 1 1 0.678599789228046 -0.733860142819578 4.1638796587263e-32 411.444127768407 31.722711740814 12.9700175423228 2.69716838912748e-30 -9.99121516709103 98.7501085580986 -0.101176751225674 0.919484419065668 PATJ other 6.54978270317647e-28 1 4.25586200120425e-26 12.9700175423228 -0.101176751225674 0.615336447793553 -7.62381310677267 20.3057555389567 -0.375450846541826 0.70761674293008 -62.2736910820809 63.2100931411335 -0.98518587756291 0.32540509822668 KANK4 other 1 1 1 -0.375450846541826 -0.98518587756291 0.467512495978234 40.2198286479567 57.364720565511 0.701124807224072 0.483835728687652 -59.0145281849816 96.0397795587157 -0.614480046248981 0.539421419068175 SYT4 other 1 1 1 0.701124807224072 -0.614480046248981 0.201432883766875 6.2074734478888 5.30557451869513 1.16999081362738 0.243032580575177 -6.50183490199463 9.06832000404173 -0.716983399251104 0.474001825272247 SLC14A2 other 1 1 1 1.16999081362738 -0.716983399251104 4.14348735349631e-10 139.556115947941 33.5840887392377 4.15542363026488 4.34830083337922e-05 -120.228754927549 52.5896024636687 -2.28616968554969 0.0230105060111579 FBXO44 other 4.57275264331853e-06 1 0.422785290029462 4.15542363026488 -2.28616968554969 2.44131333499006e-15 23.5501995171042 4.38683659104431 5.3683785635375 1.69954520459769e-07 -19.6109222943085 6.81385075575372 -2.87809683500166 0.00431714087572808 RSG1 other 3.25622372620975e-11 1 0.0019825194811632 5.3683785635375 -2.87809683500166 4.6709245692119e-15 74.8096777228628 23.8198212810526 3.14064815349265 0.00187099407671474 -188.161288001638 36.9257302594619 -5.09566870254173 6.49627046564314e-07 CASP9 other 6.18990923911961e-11 0.0101945972417338 1 3.14064815349265 -5.09566870254173 1.05327602230427e-16 384.960110371597 69.6523017560516 5.52688282606756 7.61095118956516e-08 -450.767440378753 116.234382249105 -3.87809038648049 0.000131982382736283 DCTN4 essential 1.45225697955313e-12 1 0.000905550972534463 5.52688282606756 -3.87809038648049 0.144924802104542 -3.47955748356579 80.3190042147532 -0.0433217209001037 0.965476861746033 -219.698594309142 130.44793498932 -1.68418606493947 0.0932928379805093 ATP8A2 other 1 1 1 -0.0433217209001037 -1.68418606493947 0.0171520613516487 -2.54832893502193 14.6476196138801 -0.173975635782289 0.862014979501368 -58.2561858389367 23.2061153292947 -2.51038077732019 0.0126451736719665 MTUS2 other 1 1 1 -0.173975635782289 -2.51038077732019 1.55770576653966e-21 43.4634759254384 12.5496340035075 3.46332617455543 0.00062560534958113 -119.24357664949 18.8503914655723 -6.32578781545584 1.1233524105999e-09 ZMYM5 other 2.31817772176433e-17 1.7890510491214e-05 1 3.46332617455543 -6.32578781545584 4.03453211136857e-11 50.9229589332462 19.7161486037325 2.58280458099236 0.0103287717132069 -136.296974062295 31.2287180501154 -4.36447547554042 1.81855698103616e-05 USPL1 essential 4.67077782533139e-07 0.278057362400429 1 2.58280458099236 -4.36447547554042 4.73459348517819e-14 181.657965673061 37.0250333297069 4.90635522338094 1.63833997653879e-06 -144.736222337669 55.8988692831239 -2.58925134253773 0.0101604070758538 XPO4 other 6.09768294956099e-10 1 0.0178972259037097 4.90635522338094 -2.58925134253773 2.80695188570542e-12 531.651351396509 104.173328070624 5.10352660554414 6.28211827167689e-07 -344.131314046581 164.144785878317 -2.09651078592099 0.0369640398077479 POMP other 3.39921873358927e-08 1 0.00705984451371048 5.10352660554414 -2.09651078592099 3.92607566814395e-07 101.051296179817 36.6782195329353 2.75507637684206 0.00626546886543355 -144.628113092794 58.0686147039419 -2.49064169741553 0.0133503701987732 CDK8 other 0.00361552308279377 1 1 2.75507637684206 -2.49064169741553 0.639143973089716 13.4106470876961 124.994019321383 0.107290310052474 0.914638646763092 169.210397450711 197.979994257053 0.854684323462561 0.393486467247706 ALOX5AP other 1 1 1 0.107290310052474 0.854684323462561 2.40738177532875e-05 50.40382281261 34.4169880967453 1.46450417656903 0.14421105991588 -158.647836817253 54.3202910945072 -2.92059990144815 0.00378642144923656 WASF3 other 0.19054426751727 1 1 1.46450417656903 -2.92059990144815 0.000717609834578037 103.50825571995 26.8426933782388 3.85610543105423 0.000144208013155474 22.3361889972836 73.9411347152514 0.302080690042162 0.762823975202277 CHRM3 other 1 1 1 3.85610543105423 0.302080690042162 0.000299865462380689 777.998938827844 225.242757349154 3.4540464163376 0.000640022332150666 -700.18549233967 676.640098564304 -1.03479751469847 0.30167924628354 MYH10 other 1 1 1 3.4540464163376 -1.03479751469847 1.99106125928785e-22 181.997363980885 21.8629792640814 8.32445394484216 4.11672404646046e-15 -154.724365094267 56.3227932887682 -2.74710034889414 0.00641258107253532 PEMT other 2.99156954207999e-18 1 6.03264741768316e-11 8.32445394484216 -2.74710034889414 8.27136191994062e-41 277.874100719424 19.2568179561643 14.4299074411967 2.23075351848426e-35 -123.956235011991 57.4062534015615 -2.15928104809256 0.0317091209419375 SCO1 other 1.31299599117137e-36 1 3.53730585426049e-31 14.4299074411967 -2.15928104809256 1.72910478480395e-06 420.534905313401 129.368645719151 3.2506710028205 0.0012957453450527 -800.174073044734 339.430749312435 -2.35740007252024 0.0191093900930123 MPRIP other 0.0151141049239713 1 1 3.2506710028205 -2.35740007252024 0.687464385554611 -133.293559883962 200.42363641788 -0.665059083181422 0.506576199832968 -350.899640834369 571.673099577891 -0.613811706539042 0.539852758520346 CHI3L1 other 1 1 1 -0.665059083181422 -0.613811706539042 0.553329716205164 39.3406025425524 39.7904033435944 0.988695746631218 0.323693947214304 62.073076765928 114.670946016068 0.541314769978703 0.588735354027009 PIK3C2B other 1 1 1 0.988695746631218 0.541314769978703 0.00231285579409082 89.3376913182827 25.4600018933769 3.50894283874828 0.000526298837955688 -0.349675620131056 73.5837892104391 -0.00475207411690955 0.996211891063684 DSTYK other 1 1 1 3.50894283874828 -0.00475207411690955 0.000462296545773025 -84.3505760464154 76.4055552947236 -1.10398485713565 0.270575396396006 806.637634111525 217.933380518226 3.70130372957741 0.000259615178571466 CHIT1 other 1 1 1 -1.10398485713565 3.70130372957741 9.59727441212668e-06 211.27934138519 43.649067657209 4.8404090333484 2.17107658129086e-06 -41.7360590850065 123.419807872844 -0.33816337753504 0.735499978766529 SLC41A1 other 0.078784025649148 1 0.0234867064564045 4.8404090333484 -0.33816337753504 0.864936731284764 37.3344295444094 74.0760837263894 0.504001125144648 0.614667072230911 -28.162606670706 202.473536764802 -0.139092777854818 0.889479386302179 LGR6 other 1 1 1 0.504001125144648 -0.139092777854818 0.0215412508573549 71.6717914988079 26.5519175225949 2.6993075523761 0.00738195995918007 -33.9111120246282 75.8843388892 -0.446878928129589 0.655316786289807 TMCC2 other 1 1 1 2.6993075523761 -0.446878928129589 0.0963602203519297 104.510750777805 111.451524254707 0.937723835332752 0.349221303405621 -201.667512086756 170.414882268741 -1.1833914350786 0.237691096094341 DCLK1 other 1 1 1 0.937723835332752 -1.1833914350786 0.0296425715102451 42.2605387882572 62.0570415327568 0.680995061067325 0.496456077921528 -176.429766163011 94.6477978500427 -1.86406625585248 0.0633936249716454 CCNA1 other 1 1 1 0.680995061067325 -1.86406625585248 2.23788658706285e-09 132.867691933621 34.7672069210757 3.82163836845569 0.00016434447896184 -146.175046789669 55.3167257006059 -2.64251083082577 0.0087063217958793 COG6 other 2.37327872558015e-05 1 1 3.82163836845569 -2.64251083082577 0.305185484197625 -13.2469893069492 73.7814654920315 -0.179543591586425 0.857644079287129 -165.54090857965 116.684274472082 -1.41870795639439 0.15712478827114 EPSTI1 other 1 1 1 -0.179543591586425 -1.41870795639439 0.134876950541418 5.73117116025362 3.38833409266389 1.69144216701129 0.0918977243647939 -0.513412924169635 5.28007031596876 -0.0972360013117434 0.92261058801218 TRPC4 other 1 1 1 1.69144216701129 -0.0972360013117434 0.140131503619481 -2007.57609811708 1023.77605712695 -1.96095238225341 0.0509048234405914 -1092.67859826692 1595.35908254716 -0.684910757847908 0.493983459817625 POSTN other 1 1 1 -1.96095238225341 -0.684910757847908 5.4739307889455e-10 32.9647744659993 7.74599798454449 4.2557168917128 2.87061522993842e-05 -27.7693736926036 11.82561146452 -2.34823998538419 0.0195787313406724 RFXAP other 5.99997553776317e-06 1 0.283989964697808 4.2557168917128 -2.34823998538419 0.000770985700313145 9122.40029256397 4067.55679014086 2.24272229331261 0.025720302637673 -10230.3337713125 6419.69917030131 -1.593584605746 0.112190445576852 TPT1 essential 1 1 1 2.24272229331261 -1.593584605746 1.74773265154741e-16 136.876724811246 22.8226989980985 5.9973942969081 6.36439178276896e-09 -107.185309815152 36.0617903317254 -2.97226812172039 0.00322070890316801 GPALPP1 other 2.39719010486243e-12 1 7.96758207284846e-05 5.9973942969081 -2.97226812172039 0.323287730067921 12.2453231637322 9.09360753058396 1.34658584313743 0.179234645193388 17.8481535620306 14.1876143951027 1.25800949088322 0.209467192997924 STOML3 other 1 1 1 1.34658584313743 1.25800949088322 0.830277563012014 10.3815541400595 18.5801449542527 0.558744518173595 0.576795785917915 2.27839217524209 28.7168773665935 0.0793398302383865 0.936820665240475 KL other 1 1 1 0.558744518173595 0.0793398302383865 1.2647535481967e-14 230.390518065947 33.1053890897395 6.95930555117243 2.55489373443437e-11 -29.9613835044222 51.1881583952814 -0.585318644852519 0.55881875351687 RFC3 essential 1.65417116568646e-10 1 3.4743999894573e-07 6.95930555117243 -0.585318644852519 0.696767821283377 -23.5818159062223 45.3314823767181 -0.520208355646753 0.603341504972367 -59.2084596006667 70.0628882854949 -0.845075917501458 0.398811178953061 STARD13 other 1 1 1 -0.520208355646753 -0.845075917501458 1.08304091879538e-17 215.756602355353 24.4581379576666 8.82146477089941 1.39334787095667e-16 -56.9239144424127 53.7794224895499 -1.05847016957971 0.290780223895333 FAM104A other 1.52546313412329e-13 1 2.07803901474478e-12 8.82146477089941 -1.05847016957971 0.00147338713821291 122.845458234537 55.3855488848971 2.21800561171355 0.0273867737095671 -268.585879522802 122.900807524276 -2.18538742692759 0.0297198527232345 SLC39A11 other 1 1 1 2.21800561171355 -2.18538742692759 0.000460655197321267 262.596603080095 121.299392128374 2.16486330617537 0.0312679035362879 -255.766527111757 179.384891141184 -1.42579748765161 0.155073420537222 EPHB2 other 1 1 1 2.16486330617537 -1.42579748765161 2.40593971419937e-17 577.048238391771 94.9967816799573 6.07439776576682 4.17954082455789e-09 -317.56306153439 139.838415833204 -2.27092862603058 0.0239331718043984 SRRM1 essential 3.3692779757648e-13 1 5.27458052059205e-05 6.07439776576682 -2.27092862603058 4.82249027265309e-17 511.208638905077 129.165779133839 3.95777149592672 9.67011095065371e-05 -1120.45192834764 228.191566202488 -4.91013733326758 1.57483735154366e-06 BTBD2 other 6.70663722217866e-13 0.0245706123587842 0.908603624923422 3.95777149592672 -4.91013733326758 0.410260362672479 -3.04669794456079 10.5863282093594 -0.287795530641795 0.773722415547385 24.8580374146433 24.3495218269055 1.02088400714202 0.308216528080853 PRAM1 other 1 1 1 -0.287795530641795 1.02088400714202 0.000136739834033215 44.8380524123189 17.8119444416274 2.51730250783459 0.0124072952905791 -82.9377583146122 39.5151844814628 -2.09888323698754 0.0367593970594124 KMT5C other 0.99614969093197 1 1 2.51730250783459 -2.09888323698754 2.68918609956481e-29 91.986289775339 8.4924931923046 10.8314823094226 5.76270598753182e-23 -25.8133043277946 19.5335100387352 -1.32148826691191 0.187449068803748 ZNF414 other 4.20158436196006e-25 1 8.94544850444564e-19 10.8314823094226 -1.32148826691191 1.49721291906643e-24 115.018503352667 10.4649736941843 10.9908067343338 2.18689609553208e-23 32.2849427888713 28.7159577032024 1.1242857759632 0.261913025152686 PDE6B other 2.28639384870635e-20 1 3.40127949738104e-19 10.9908067343338 1.1242857759632 5.8275381223223e-16 284.572985276152 44.858768559067 6.34375383937358 9.36347741162598e-10 -301.889179900983 99.3572035779828 -3.03842267122623 0.0026103966853442 HSPBP1 other 7.89514864812225e-12 1 1.21116580319382e-05 6.34375383937358 -3.03842267122623 3.49522042527147e-12 152.334186269663 86.6007995273588 1.75903902852003 0.0797035748547702 -807.241058707221 153.225859780461 -5.26830823376563 2.8176435330623e-07 CSNK1G2 other 4.21943009738772e-08 0.00443778856457312 1 1.75903902852003 -5.26830823376563 1.77153072707493e-10 92.6871665177222 14.5495008553259 6.3704705363685 8.04897084832276e-10 15.6283011459963 25.3111180878715 0.617448075258479 0.537457681555852 SLF1 other 1.99049192494139e-06 1 1.0433076013596e-05 6.3704705363685 0.617448075258479 2.73655139798026e-10 655.671893554181 222.909179400365 2.94143065493295 0.00355251879002511 -1256.83658618275 343.780204495033 -3.65593064914507 0.000308345572861888 CNDP2 other 3.04797094707041e-06 1 1 2.94143065493295 -3.65593064914507 0.0447593730678184 48.8090109029016 24.4516114604218 1.99614700167739 0.0469147562906192 -42.5045867666193 53.4353014212541 -0.795440198447407 0.427051073548603 MACROD1 other 1 1 1 1.99614700167739 -0.795440198447407 1.69117868990761e-12 287.53933736905 46.2783931304218 6.21325240396109 1.9478764809727e-09 -229.861800848225 94.5580246981775 -2.43090738815587 0.0157099806496094 WDR74 essential 2.06763506628105e-08 1 2.49074965621979e-05 6.21325240396109 -2.43090738815587 0.00333717718434967 317.851882871144 169.895600141863 1.8708658882616 0.0624373118345936 -746.314517029595 361.015923564999 -2.06726204667043 0.039655351263555 RTN3 other 1 1 1 1.8708658882616 -2.06726204667043 0.736176236436546 67.9378231212286 94.2220717142354 0.721039368856972 0.471506846510222 -8.87627037015157 195.492241679607 -0.0454047193581161 0.963818158648108 RARRES3 other 1 1 1 0.721039368856972 -0.0454047193581161 0.10030605612762 33.5162076625189 15.5785356403234 2.15143505373931 0.0323256963798117 20.38779953215 32.3223932461288 0.630763921993673 0.528726471225089 HRASLS2 other 1 1 1 2.15143505373931 0.630763921993673 0.60891766959535 -937.224917425772 1565.59787824262 -0.598637064121348 0.549922454334546 -3123.73920663908 3151.41281758515 -0.991218665231146 0.322476246389213 MYH11 other 1 1 1 -0.598637064121348 -0.991218665231146 2.86453117308632e-10 450.79587650331 83.9330314412512 5.37089949883252 1.70065025066038e-07 -166.444592234895 169.043642084197 -0.984624977211465 0.325696384720548 FOPNL other 3.18707738317584e-06 1 0.00198363845237026 5.37089949883252 -0.984624977211465 2.99568545277666e-21 224.272030090336 21.2673359079959 10.5453748913617 5.19443730775314e-22 -38.9490271589649 122.921910056421 -0.316859924655314 0.751593846728099 MED10 other 4.44979117155446e-17 1 8.02436675301705e-18 10.5453748913617 -0.316859924655314 1.39377996211765e-09 362.135746801641 56.7647202534676 6.37959185185132 7.9580274547006e-10 -308.894936857163 372.897148854162 -0.82836497357605 0.408214923718538 PDZD2 other 1.49441087538255e-05 1 1.03191742005103e-05 6.37959185185132 -0.82836497357605 6.65287322232123e-09 236.409039307893 51.1198662220401 4.62460207311666 5.81771793951437e-06 -445.808843089713 163.323031776876 -2.72961405528374 0.00675611540983848 MORC2 other 6.85245941899087e-05 1 0.0608707828011389 4.62460207311666 -2.72961405528374 4.62714782578283e-05 123.75852290803 38.0008684938066 3.25672880155885 0.00127051771627347 -163.6306768404 94.350502408031 -1.73428516716061 0.0840046238328581 LARGE1 other 0.355457495976637 1 1 3.25672880155885 -1.73428516716061 0.0238914378484575 12.8723619671242 9.81678242280343 1.31126079938605 0.190879585147356 -49.929097394072 27.6146676651422 -1.80806439532485 0.0717050073553788 GSTT2B other 1 1 1 1.31126079938605 -1.80806439532485 0.127170130122156 7.81340988436625 5.36685438528188 1.45586396116761 0.146583465221628 -13.3295481605553 15.7992859901326 -0.843680414980795 0.399589368109945 MYO18B other 1 1 1 1.45586396116761 -0.843680414980795 8.27925940630508e-10 78.239510122536 12.2681804562435 6.37743391545225 7.73723389006493e-10 7.9708354923361 34.5104649939273 0.230968649473101 0.817513435337374 SLC2A11 other 8.98961986336605e-06 1 1.00382872489702e-05 6.37743391545225 0.230968649473101 0.0321297493986478 195.577412172048 83.1620500270649 2.35176275847455 0.0193954365853346 388.089423112512 196.423778865724 1.97577617818773 0.0491869687103467 C1QTNF6 other 1 1 1 2.35176275847455 1.97577617818773 1.00713217595373e-08 251.872135902402 69.7145906303024 3.61290418010319 0.000361245844373771 -631.057929377249 173.917630174186 -3.62848739800109 0.000341089015448871 FAM83F other 0.000102606626086166 1 1 3.61290418010319 -3.62848739800109 0.000675681062153051 24.068641996527 6.35398688104221 3.78795903220045 0.000186861768280489 7.99278144406502 20.1600032333262 0.396467269948265 0.692070068118281 SEC14L4 other 1 1 1 3.78795903220045 0.396467269948265 0.1393469958665 -67.9543112434308 49.8236581795444 -1.36389646457815 0.17372361356516 -237.555510947405 125.984911457088 -1.88558699768042 0.0604123403512649 GIMAP6 other 1 1 1 -1.36389646457815 -1.88558699768042 0.0488001044050395 -89.4646147185937 49.3736613601605 -1.8119906900561 0.0710862891799498 -284.393088370091 124.847042189405 -2.27793212704742 0.0235037292378816 GIMAP4 other 1 1 1 -1.8119906900561 -2.27793212704742 5.66947615371165e-17 238.560078738773 34.199739234356 6.97549408502867 2.30192806620441e-11 -289.690809708772 94.4017252052948 -3.06870249541291 0.00236621058682692 ADCK2 other 7.87093374419788e-13 1 3.13476564055717e-07 6.97549408502867 -3.06870249541291 6.56202126260248e-19 768.965623846598 96.6050209703648 7.95989293436923 4.64327303542359e-14 -662.975883321323 266.659361950186 -2.48622766691076 0.0135088319492616 MKRN1 other 9.4473420117688e-15 1 6.69606404438436e-10 7.95989293436923 -2.48622766691076 5.0603398368965e-06 219.154637385736 73.9980029343007 2.96162908045388 0.00332942626030051 -466.563029258934 186.680559874512 -2.49925878502058 0.0130329750399849 AGAP3 other 0.0425068546299306 1 1 2.96162908045388 -2.49925878502058 9.79744350984052e-07 73.195220237701 15.943187261821 4.59100298050071 6.79888441988002e-06 -33.4712519435651 41.1310593688335 -0.813770723564866 0.416501434414736 KRBA1 other 0.00872756267856593 1 0.070776386810951 4.59100298050071 -0.813770723564866 0.000468316817399838 42.6691658407539 15.2347563951906 2.80077769108432 0.00547061811690935 -58.8636537874717 39.4181026583226 -1.4933152490292 0.136535427358444 ZNF767P other 1 1 1 2.80077769108432 -1.4933152490292 1.15404444768383e-09 62.7835716137799 11.5489825769834 5.43628594079832 1.2275697534839e-07 -31.5997371315148 29.0319681405117 -1.08844625960511 0.277379638396183 ACTR3B other 1.24186723015257e-05 1 0.0014442358149738 5.43628594079832 -1.08844625960511 0.269407458386308 3499.33632458454 2180.9659085237 1.60448923612623 0.109797326914493 889.413492296622 5045.93350344912 0.176263419184709 0.8602216247407 NTS other 1 1 1 1.60448923612623 0.176263419184709 2.56795336823384e-05 863.740895000565 322.646441331016 2.6770507414784 0.00787865326030672 -2205.5153460348 739.444925913603 -2.98266343948446 0.00311670268937605 BTG1 other 0.202688559354697 1 1 2.6770507414784 -2.98266343948446 0.364117317581848 11.1535764662592 9.61408692295022 1.16012852345177 0.247048537438486 24.6837372488092 22.4691259718703 1.09856241314021 0.272963647685294 LRRIQ1 other 1 1 1 1.16012852345177 1.09856241314021 0.000651509246809266 85.551855200723 26.8856664327847 3.1820619144631 0.00163385897728994 -80.7134883992088 63.0791731884781 -1.27955843932894 0.20180299143023 C12orf29 other 1 1 1 3.1820619144631 -1.27955843932894 4.50587690786829e-22 765.597192754317 70.8378346314622 10.8077441488349 7.32109571690727e-23 -75.2177304263397 545.517681934609 -0.137883212437019 0.890435489981628 ATP13A3 other 6.74890243260512e-18 1 1.13535552377798e-18 10.8077441488349 -0.137883212437019 0.817947240030311 -226.020247920083 767.257722459549 -0.294581913357019 0.768539642617402 -729.809021350535 1168.33384185861 -0.624657948955358 0.532723077806853 SFTPD other 1 1 1 -0.294581913357019 -0.624657948955358 0.364369138507881 -1.76993490879747 7.42958044548276 -0.238228110158442 0.811884871814896 -14.2195900391324 11.3034713296918 -1.25798435050483 0.20948425482613 DYDC2 other 1 1 1 -0.238228110158442 -1.25798435050483 1.72711440899464e-11 194.937502088276 49.3204635506601 3.95246694889726 9.88365655416503e-05 -189.1644792676 75.1022309396545 -2.51875978783634 0.0123551019446055 TMEM254 other 2.03074112209589e-07 1 0.928075350436096 3.95246694889726 -2.51875978783634 0.000258375967597756 267.947152702657 64.9266994885908 4.12691781367605 4.89251200687997e-05 316.804317959183 407.760580585 0.776937087701502 0.437871031908952 TMTC1 other 1 1 0.472567734744536 4.12691781367605 0.776937087701502 7.91412015643671e-15 479.733719285377 58.1295061923284 8.25284353350812 7.25059342079738e-15 -258.913741464522 349.031795695217 -0.741805602405952 0.458859584768063 KRAS essential 1.04078594177299e-10 1 1.05858663943642e-10 8.25284353350812 -0.741805602405952 9.38841147847958e-29 354.311345713232 28.0778495397405 12.6188918140526 4.76427539494826e-29 16.4355206512605 183.055809631945 0.0897842067089049 0.928524775047573 IPO8 other 1.46327781303583e-24 1 7.50278089196452e-25 12.6188918140526 0.0897842067089049 3.57093470812716e-15 823.458831139177 104.904795481487 7.84958235092788 9.64056712765321e-14 74.4869872916782 175.24746183356 0.42503889364413 0.671144370595615 LARS essential 4.74434385321774e-11 1 1.38380700550334e-09 7.84958235092788 0.42503889364413 0.289602166911413 -122.19687236112 305.958160994861 -0.399390792400445 0.689918691625937 -783.085929900696 510.073058354858 -1.53524268156093 0.125886584739673 SPINK5 other 1 1 1 -0.399390792400445 -1.53524268156093 1.05281694905416e-11 128.142648066973 18.7483461444418 6.83487743824077 5.48485361199895e-11 -17.9313588900082 60.2128356214679 -0.297799608753438 0.76608598165449 IMPA1 other 1.2479039297139e-07 1 7.39193721289098e-07 6.83487743824077 -0.297799608753438 1.51093805522338e-05 107.179968386122 25.3495355518208 4.22808410698569 3.22916835133734e-05 -66.8213847127546 84.2783556706497 -0.792865311396024 0.428552439551839 LRRCC1 other 0.121932701056527 1 0.317459540619974 4.22808410698569 -0.792865311396024 1.43880481798183e-06 131.137869898122 26.7543597969811 4.90155140669519 1.64252017169207e-06 -31.7757853498818 88.9489058330516 -0.357236382530908 0.721193911716414 E2F5 other 0.0126514107645142 1 0.0179379627950491 4.90155140669519 -0.357236382530908 8.34594183149035e-08 147.362834032531 26.8360314299823 5.49123049050731 9.34726623217546e-08 -33.1765395471549 61.309016453754 -0.541136385252246 0.588868182060687 CCDC59 essential 0.000803046523026001 1 0.00110709021253886 5.49123049050731 -0.541136385252246 1.12960790273194e-08 244.8374988598 96.0215087152756 2.54981932835273 0.0113308808192806 -454.658305208428 149.904767778252 -3.03298095148638 0.0026572262418655 SWAP70 other 0.000114689090364374 1 1 2.54981932835273 -3.03298095148638 0.00948754231376081 -6.04142024800535 19.423480904245 -0.311036949442209 0.756017982243999 -83.0585013525128 31.1227775918859 -2.66873678312592 0.00808516969843128 ARNTL other 1 1 1 -0.311036949442209 -2.66873678312592 0.246359732064725 -55.2817812179309 72.1045925361842 -0.766688767989208 0.443933944129623 -185.943370205988 112.246097032846 -1.65656869255398 0.0987640079724267 LYVE1 other 1 1 1 -0.766688767989208 -1.65656869255398 0.000205400947740537 -4.1365342393207 30.7484415569824 -0.134528256713595 0.893085095579818 -165.205691167557 47.9992191323418 -3.4418412247928 0.00066938700370277 AMPD3 other 1 1 1 -0.134528256713595 -3.4418412247928 0.189762261778969 7.41615499290601 13.3447676194308 0.555735041958141 0.578859110715241 -22.8686285743425 20.9346301331129 -1.09238273754694 0.27565327821717 MICALCL other 1 1 1 0.555735041958141 -1.09238273754694 9.15212398344683e-19 204.968725974381 43.6390949216451 4.69690598172137 4.20961463321457e-06 -279.395240701406 68.1275318187292 -4.10106212925501 5.44754970521861e-05 SBF2 other 1.31314674914495e-14 0.821163642564654 0.0445587708925762 4.69690598172137 -4.10106212925501 0.213587437324383 -135.331956338506 171.096590765332 -0.790968164433626 0.429667236919284 -467.216267176192 268.408109219783 -1.74069356002063 0.0828936374682315 MICAL2 other 1 1 1 -0.790968164433626 -1.74069356002063 7.61017138101725e-14 204.136309054588 37.2090589066153 5.4861991959247 9.64709807180453e-08 -109.750151170932 60.5251834444134 -1.8132972908992 0.0709258157038872 RRAS2 other 9.73721428201157e-10 1 0.00114154111483663 5.4861991959247 -1.8132972908992 1.3313849857048e-09 195.350678175091 133.588457912272 1.46233201002573 0.144804683832279 -1098.84242125322 220.031689762019 -4.99401891810087 1.05847611413379e-06 HSD17B4 other 1.42897550515697e-05 0.0165693850906503 1 1.46233201002573 -4.99401891810087 0.0424587612224404 39.3318641789865 35.8801778407341 1.09620036872654 0.273986287142935 -194.023951992252 103.054656404934 -1.88272862926127 0.0608325636692954 ZFC3H1 essential 1 1 1 1.09620036872654 -1.88272862926127 7.55483326569956e-05 57.3995877750112 13.1791176347694 4.35534376167783 1.88610957092481e-05 47.4346113551508 22.9292042786513 2.06874214991036 0.0395185606340119 TEX15 other 0.567745719917322 1 0.189403123112269 4.35534376167783 2.06874214991036 3.67976391200145e-17 438.261837478903 232.225815333461 1.88722273124368 0.0601990129060981 -2412.29065903149 404.02956450661 -5.97057955889272 7.38990637334583e-09 SARAF other 5.13327065724203e-13 0.000117462561804332 1 1.88722273124368 -5.97057955889272 1.14284838692661e-09 88.5172018961403 22.7302507265481 3.89424661263218 0.000125755876640201 -75.3399540468533 41.7189401622845 -1.80589328860668 0.0721095363531805 RNF122 other 1.2301620036878e-05 1 1 3.89424661263218 -1.80589328860668 0.251131673783447 -13.3751730687812 24.8605367561094 -0.538008217601912 0.591038795825616 -71.6358098856124 45.8367615970915 -1.56284622625168 0.119324076041172 DUSP26 other 1 1 1 -0.538008217601912 -1.56284622625168 2.26256776647158e-12 270.628042877944 47.0930460147816 5.74666677523896 2.45275219094972e-08 -348.718149359819 110.358625601065 -3.15986310504083 0.00175801702591168 DPF2 other 2.75150866080609e-08 1 0.000298769744379585 5.74666677523896 -3.15986310504083 4.54808003577374e-12 304.566951750009 51.0178937473189 5.96980646160083 7.42091357159993e-09 -304.262312674816 117.285658009176 -2.59419879497127 0.00999698390826405 MEN1 ts 5.45587681091418e-08 1 9.26278432007104e-05 5.96980646160083 -2.59419879497127 0.622723929886708 2.02237088854871 3.11415836390778 0.649411703652396 0.516620305379092 -2.3268746556356 6.40059651031485 -0.363540281266868 0.7164837190444 GSC other 1 1 1 0.649411703652396 -0.363540281266868 0.439123462320576 19.1780510000276 15.2602211390514 1.2567348025482 0.209923900468927 9.84206773478098 31.0296320463013 0.317182869590429 0.751347283145295 UNC79 other 1 1 1 1.2567348025482 0.317182869590429 0.00256459761679853 9.29952439054757 4.04363554698696 2.29979291716261 0.0222174282163889 -12.4066784531488 8.65698389401676 -1.43314098825153 0.152965940823757 CATSPERB other 1 1 1 2.29979291716261 -1.43314098825153 1.89754359770616e-12 222.126691530018 37.5299267132794 5.91865508363546 9.74473112983467e-09 -106.935117716752 68.9031693763472 -1.55196224911913 0.121833987368924 COX16 other 2.31481343484174e-08 1 0.000121078284288196 5.91865508363546 -1.55196224911913 0.139557113484872 -15.700377733995 74.1575209308664 -0.21171659377114 0.832486692482226 -249.093965845774 134.945217705252 -1.84588954007875 0.0659948189139102 TTC9 other 1 1 1 -0.21171659377114 -1.84588954007875 1.40058768271831e-22 157.000782119844 18.0512862277645 8.69748449716356 3.28528758717427e-16 -61.8298366266227 32.8481146522737 -1.882294837349 0.0608634306617719 MED6 other 2.10676399234489e-18 1 4.87963765322994e-12 8.69748449716356 -1.882294837349 1.95560095827701e-20 568.485496274824 73.0864530397598 7.77826084904629 1.54575352334583e-13 -279.412215995642 132.771985751561 -2.10445158603314 0.0362600640744813 EIF2S1 essential 2.87434228847555e-16 1 2.21135499049855e-09 7.77826084904629 -2.10445158603314 0.140101046330497 -182.868079719642 204.187433692951 -0.895589294660669 0.371261131474433 -664.29632594176 340.454670361313 -1.95120344578256 0.052055578849585 LOXL2 other 1 1 1 -0.895589294660669 -1.95120344578256 6.737766598779e-33 200.962586035828 26.1206137368503 7.69363951629955 2.69083397578752e-13 -200.665102403819 44.4399636498411 -4.51542003915515 9.4488825152554e-06 ELP3 essential 1.06133299463967e-28 0.145456097439842 3.83820558306331e-09 7.69363951629955 -4.51542003915515 0.513887023702654 -66.2056980044105 106.107098450578 -0.623951639156803 0.533180362254017 -203.503224304978 176.919101105457 -1.15026146432699 0.251042777370164 PEBP4 other 1 1 1 -0.623951639156803 -1.15026146432699 0.332759028523429 -56.6119177797004 59.7589252476878 -0.947338285370031 0.344307286805196 -148.730201496706 100.086864135755 -1.48601120417734 0.13843428807537 ADAMDEC1 other 1 1 1 -0.947338285370031 -1.48601120417734 9.50484520022081e-11 122.659187643339 47.1921714993774 2.59914269138808 0.00986150585182666 -336.863043296595 75.3803522095939 -4.46884411417915 1.15971415014567e-05 CTIF other 1.08269691675715e-06 0.178271259160392 1 2.59914269138808 -4.46884411417915 0.0206710049191211 6.85594485927626 3.00489013952979 2.28159584574666 0.0232947437296025 -1.13689450507372 4.76852019576193 -0.238416627884715 0.811739490158265 MRO other 1 1 1 2.28159584574666 -0.238416627884715 5.84946080882007e-12 293.718115487182 98.7123555086043 2.97549495170926 0.0031910876395161 -694.940519714349 164.026866436804 -4.23674813041737 3.11811653468953e-05 MBD2 other 6.99244545086351e-08 0.473579539288646 1 2.97549495170926 -4.23674813041737 7.9993139166576e-19 369.280797344715 44.5022213648804 8.29803066046808 5.03875828680086e-15 -106.808044967042 77.206994233833 -1.38339856417098 0.167681229003943 IER3IP1 other 1.14886146471036e-14 1 7.37523050439042e-11 8.29803066046808 -1.38339856417098 3.15418369005736e-16 80.2214517178207 17.7906880481907 4.50918207887856 9.69719433441204e-06 -125.50257111086 27.4902843793605 -4.56534277270284 7.57222481554364e-06 MRPS36 other 4.30262197160725e-12 0.116801567779761 0.0996774605634214 4.50918207887856 -4.56534277270284 1.74063385072182e-12 936.665751609807 132.151733399445 7.08780526380702 1.18096553897265e-11 165.187996443215 204.201699368543 0.808945258310922 0.419256258317122 CCNB1 other 2.12670643881192e-08 1 1.62158378156335e-07 7.08780526380702 0.808945258310922 4.23623883796765e-17 118.66565612561 20.9145022961076 5.67384556637021 3.58116962542723e-08 -116.722821319234 32.3172220329757 -3.61178387177378 0.000362279676377575 CDK7 essential 5.90065707740514e-13 1 0.000432784349232881 5.67384556637021 -3.61178387177378 0.190653982183275 -42.9741938885117 23.5347298785537 -1.82599053017696 0.0689479303044673 -33.6891254145761 37.1234642521631 -0.907488729654672 0.364951684837999 CD180 other 1 1 1 -1.82599053017696 -0.907488729654672 0.000185352497166194 62.8662973290284 23.635528097465 2.65982198788996 0.00828220463488105 -150.970802759026 66.5680907710761 -2.26791546836166 0.0241187718897008 IRAK2 other 1 1 1 2.65982198788996 -2.26791546836166 0.000169939775610751 27.752266921198 14.1128072098209 1.96645972049314 0.0502621995296167 -116.210279750709 39.2148860950981 -2.9634226010218 0.0033117032219473 CAMK1 other 1 1 1 1.96645972049314 -2.9634226010218 1.71625596545179e-25 293.909831831698 26.5128950955051 11.0855427433697 8.48570082901888e-24 -50.5563943063338 74.5816333046526 -0.677866547918306 0.498434651263593 THUMPD3 other 2.63668403972358e-21 1 1.32139333309482e-19 11.0855427433697 -0.677866547918306 4.14586287465173e-16 232.589174591377 28.4932651103242 8.16295267287924 1.21362835720492e-14 -84.4279658133957 79.2737325681214 -1.06501817283354 0.287808743455951 VHL ts 5.63842586528579e-12 1 1.76655743674748e-10 8.16295267287924 -1.06501817283354 0.00893075557609955 1264.91471466321 462.431450133373 2.73535615775784 0.00665198037884261 -545.544636931101 1283.76436811303 -0.424956986252065 0.671212876869412 BHLHE40 other 1 1 1 2.73535615775784 -0.424956986252065 1.24019796194151e-16 1090.77968321431 122.912005181528 8.8744763508116 1.05808601626461e-16 284.942808075317 341.361984575502 0.834723317037355 0.404622551583045 ARL8B other 1.70713249461249e-12 1 1.57961661368144e-12 8.8744763508116 0.834723317037355 0.00024635407445029 404.530314561761 101.365276442057 3.99081745505822 8.52054297443352e-05 94.2788653043059 281.520522606403 0.334891625063222 0.73797077042006 EDEM1 other 1 1 0.804594873075757 3.99081745505822 0.334891625063222 0.822481519516271 -5.94025430602404 11.0034389283929 -0.539854344144722 0.58976676643581 -14.6963842291999 30.6449725285215 -0.479569176168192 0.631943210280929 CNTN6 other 1 1 1 -0.539854344144722 -0.479569176168192 0.0631320464366469 218.457667446 94.4992313335518 2.31174015241367 0.021592620115337 85.8734276225552 261.238101666507 0.328717086346692 0.742640390611137 CHL1 other 1 1 1 2.31174015241367 0.328717086346692 0.0016874447298146 107.039135402517 50.5147712793982 2.11896704056089 0.0350096846305166 -127.316711069552 89.42999425243 -1.42364664264856 0.155707631379379 MEIS2 other 1 1 1 2.11896704056089 -1.42364664264856 5.04456890114891e-11 59.7990025040797 12.3328501670068 4.84875772382737 2.10789052032256e-06 -45.7406623402991 21.9671946106669 -2.08222593512638 0.0382704437586757 DPH6 other 5.81991914125549e-07 1 0.022826346444573 4.84875772382737 -2.08222593512638 9.96788724563161e-11 83.0455260185172 28.7784408153824 2.88568538341829 0.00422460353340927 -208.897225391635 51.3010670357826 -4.07198597342876 6.14756594501547e-05 KATNBL1 other 1.13444524742533e-06 0.924655393789777 1 2.88568538341829 -4.07198597342876 2.27906536817148e-09 168.603474206184 51.5348268964307 3.27164141921008 0.00120940628834778 -295.602093328757 91.7934662076164 -3.22029557812068 0.00143848846207918 EMC7 essential 2.41580929026177e-05 1 1 3.27164141921008 -3.22029557812068 0.514664228416819 973.108304389012 865.462944347584 1.12437893585678 0.261839954855966 1168.55037364488 1288.5888570013 0.906845009015704 0.365288490118355 GSTM1 other 1 1 1 1.12437893585678 0.906845009015704 3.53693107307396e-13 266.804462742583 64.5848633445118 4.13106800767513 4.8199752727036e-05 -264.323965848474 96.4851313568468 -2.73953055907528 0.00656257776122253 PRPF38B essential 4.42859139659591e-09 1 0.465850610106803 4.13106800767513 -2.73953055907528 0.00240638874279016 39.4023611862987 20.183259860015 1.95222979140048 0.0519367703560836 -27.8516310143956 29.428975160038 -0.946401662407045 0.344783745376399 TSPAN2 other 1 1 1 1.95222979140048 -0.946401662407045 0.0827162112276257 413.843403884946 259.190279926617 1.59667794641881 0.111494369394434 861.580100641348 386.573719831839 2.22876014700673 0.0266440976085436 GSTM5 other 1 1 1 1.59667794641881 2.22876014700673 0.664267190967805 611.427218187559 728.548612806089 0.839240110323697 0.402068869340876 283.485001578777 1084.73693804809 0.261339861892129 0.794027478203889 GSTM3 other 1 1 1 0.839240110323697 0.261339861892129 2.00571727937081e-07 115.080971614495 111.620644823458 1.03100077764745 0.303473461706421 -623.509850779759 165.809697098591 -3.76039436589175 0.00020846914133544 VAV3 other 0.00188417081224094 1 1 1.03100077764745 -3.76039436589175 0.291744670960861 22.665756281537 14.4667408197989 1.56674931581805 0.118331657277886 23.3109148738759 21.2588456259524 1.09652778349443 0.273814182081902 CHIA other 1 1 1 1.56674931581805 1.09652778349443 8.03316257780998e-17 188.954463914883 26.730073202074 7.06898415452981 1.31506003412249e-11 -7.68799165805111 39.8529455788295 -0.192908994464266 0.847174201884402 PSRC1 other 1.11154870589157e-12 1 1.80347333079559e-07 7.06898415452981 -0.192908994464266 0.314980181500577 10.0753600181427 6.77456426285568 1.48723366215374 0.138213245829192 6.82453591362087 12.0245319485694 0.567551065006968 0.570849150648691 HMGCS2 other 1 1 1 1.48723366215374 0.567551065006968 0.0698653118594015 -29.5094459987563 16.4302063457767 -1.79604841094047 0.073592433670122 -0.835689321156536 24.1488368678851 -0.0346057793892301 0.97241938163612 PTPN22 other 1 1 1 -1.79604841094047 -0.0346057793892301 0.000375285909006408 266.107464453925 208.834595977155 1.27424990676849 0.203662471975415 -678.753050025189 311.359932520074 -2.17996273486933 0.0301177122596642 SORT1 other 1 1 1 1.27424990676849 -2.17996273486933 0.0345686456018386 -68.1771838204643 89.5252972929615 -0.761540993238617 0.446991353965705 -318.672565905182 132.025482139587 -2.41372014508727 0.0164491035609955 WNT2B other 1 1 1 -0.761540993238617 -2.41372014508727 4.35809481447507e-06 1017.82951465538 425.766456215927 2.39058173746592 0.0175072603661097 -1604.56270082522 727.392415468414 -2.20591068411394 0.0282326642834155 PTGFRN other 0.0368259011823143 1 1 2.39058173746592 -2.20591068411394 3.84011509374715e-13 151.810921918768 87.5755457091603 1.73348530904888 0.0841385010022937 -638.422876757968 128.042943431362 -4.98600594182839 1.09726691402585e-06 LAMTOR5 other 4.80244793624018e-09 0.0171689354037625 1 1.73348530904888 -4.98600594182839 0.000820748165748352 399.465199709105 209.884936175127 1.90325807553808 0.0581789399705809 -620.83512581652 370.975467933288 -1.67352070279796 0.0955010592073753 NOTCH2 og 1 1 1 1.90325807553808 -1.67352070279796 1.042476772925e-05 107.359169278717 26.5394679567429 4.04526456422198 6.84680969551132e-05 7.73768439052952 45.6265826028579 0.169587200029416 0.86546320655925 TRIM45 other 0.0852329009543482 1 0.653117176854825 4.04526456422198 0.169587200029416 4.58274346773226e-15 75.8736526239909 35.4566410686094 2.13989961646885 0.0332493827026047 -268.886836661384 52.1034605016756 -5.16063298046657 4.74273402690406e-07 CEPT1 other 6.07396819213234e-11 0.00745368079668242 1 2.13989961646885 -5.16063298046657 0.308318837503183 13.8194540697969 14.7030555282707 0.939903548838892 0.348107133617439 -10.7879994073439 25.0951205164042 -0.42988434346398 0.667622660372596 CD101 other 1 1 1 0.939903548838892 -0.42988434346398 0.00633143717610564 -1.30415459503178 143.769565409003 -0.00907114514342204 0.992769172042853 -649.670535803048 250.328477062043 -2.59527219367067 0.00997637245864596 VTCN1 other 1 1 1 -0.00907114514342204 -2.59527219367067 0.0316528541180445 18.1391362414871 12.641168727972 1.43492556992372 0.152457115543581 -13.8879000547827 18.4319402846484 -0.753469240910557 0.451819684581891 NGF other 1 1 1 1.43492556992372 -0.753469240910557 2.56519990448521e-15 51.1869307581899 19.1604467300128 2.6714894219043 0.00800524877164919 -130.628419468858 28.161697586824 -4.63851367859214 5.44968419997017e-06 AP4B1 other 3.41941147267878e-11 0.0842684667841387 1 2.6714894219043 -4.63851367859214 1.75400367484125e-12 181.718084064228 31.3699539661522 5.79274308978265 1.95750510066351e-08 -162.564312858865 69.5159399778829 -2.33851851691261 0.0201042413216441 NAPG other 2.14269088918607e-08 1 0.0002395594742192 5.79274308978265 -2.33851851691261 0.00131113408811105 115.218754630316 50.8804794048303 2.26449821185013 0.0243969831781338 -206.341180174841 115.478147334333 -1.7868417959412 0.0751697885879817 SPIRE1 other 1 1 1 2.26449821185013 -1.7868417959412 2.2298840079804e-11 173.063099152569 33.4464740343989 5.17433015434085 4.5539318029766e-07 -296.542253820816 88.7972278243112 -3.3395440498158 0.000961141029378288 PPHLN1 other 2.60829532413468e-07 1 0.00516506945093606 5.17433015434085 -3.3395440498158 0.179921803529346 -112.752685857903 61.5605843308757 -1.83157270327195 0.0681086946160386 -139.590180425994 153.495588458574 -0.909408419015681 0.363939690014414 FKBP11 other 1 1 1 -1.83157270327195 -0.909408419015681 3.31435087080678e-06 461.2870720129 199.734890806141 2.30949670411174 0.0216652832779511 -1768.77395833076 498.020363731683 -3.55160970743701 0.000451110992492352 ARF3 other 0.0282415837701446 1 1 2.30949670411174 -3.55160970743701 0.000939946705915093 822.247393808412 228.343218767105 3.60092757844081 0.000377256666532332 47.1149034401301 581.524196838459 0.0810196784523795 0.935486326122703 TMEM106C other 1 1 1 3.60092757844081 0.0810196784523795 0.0440538299833762 640.744451938941 405.909811109128 1.57853896211116 0.115643817061277 -1398.58334623364 1025.71184348196 -1.36352461475525 0.173883227830416 SLC38A2 other 1 1 1 1.57853896211116 -1.36352461475525 0.616024423005864 4.1321944124622 4.47455348106237 0.923487545729617 0.35659965662042 -0.435446879210107 11.6286446467116 -0.0374460560486081 0.970157758080286 PLEKHA8P1 other 1 1 1 0.923487545729617 -0.0374460560486081 1.01496733850983e-06 1903.70502794422 390.551847959283 4.87439769621239 1.86081424325926e-06 -706.482245845796 1179.1330179165 -0.599153984419954 0.549570743464099 YWHAQ other 0.00902914944338343 1 0.020247519780904 4.87439769621239 -0.599153984419954 6.88159344551001e-05 310.547220256886 78.9416750851847 3.93388181745294 0.000106351515582823 -167.370697530672 237.481173851002 -0.704774592514361 0.481558010459381 KIDINS220 other 0.519904384808281 1 0.994812076761729 3.93388181745294 -0.704774592514361 0.00471950326934684 231.139558900736 79.4665557639866 2.90863944811216 0.00393082798149519 -130.553476015384 239.921127530264 -0.544151644164459 0.586784541715764 GRHL1 other 1 1 1 2.90863944811216 -0.544151644164459 5.98957938698886e-10 314.715793692233 48.2915289780803 6.5169979156196 3.48362889190805e-10 14.6167583466833 149.123432160095 0.09801785095042 0.921990575503536 ROCK2 other 6.55200089142711e-06 1 4.57226292062932e-06 6.5169979156196 0.09801785095042 0.982464304000151 -2.78929764014508 55.8266368308007 -0.0499635621719232 0.960188366160711 25.2933606939657 164.241271840518 0.154001247131879 0.877723796484367 RSAD2 other 1 1 1 -0.0499635621719232 0.154001247131879 0.0725952330818201 116.321808391867 51.1949522592123 2.27213432689421 0.023870965644317 145.123396301046 160.120412476561 0.906339136006718 0.365570519170608 MYCN og 1 1 1 2.27213432689421 0.906339136006718 0.0111344952649149 121.119401026033 56.4228098772077 2.146638944243 0.0327130075403669 -264.547349752853 175.344050201039 -1.50873297069127 0.132536289552607 LPIN1 other 1 1 1 2.146638944243 -1.50873297069127 0.959459003988388 4.52746995416138 23.2591263419115 0.194653483007363 0.845811158643621 -9.04336041361662 67.4741383082496 -0.13402706044652 0.893481394495127 CMPK2 other 1 1 1 0.194653483007363 -0.13402706044652 2.71973175742135e-11 423.970449094296 65.2656471794212 6.49607362244893 3.92933481594092e-10 -206.640482696467 197.04651233136 -1.04868886158702 0.295255681081163 IAH1 other 3.16984736327458e-07 1 5.15096501021695e-06 6.49607362244893 -1.04868886158702 2.24298092462863e-16 6999.46594519419 1044.17684106005 6.7033338319286 1.17169486448635e-10 -2814.76889087793 1992.82633614321 -1.41245066859436 0.158960428437975 LDHA other 3.06974369344674e-12 1 1.56292377973834e-06 6.7033338319286 -1.41245066859436 0.402885049085257 -84.9291312372166 64.0963193641711 -1.32502352833524 0.186275356488887 -116.179503870579 122.328736145011 -0.949731907087286 0.34309157604339 SAA2 other 1 1 1 -1.32502352833524 -0.949731907087286 0.0381423503346839 8.97538691765449 5.52107597533211 1.62565901243817 0.105201927948386 -10.4840310321743 10.6486657062023 -0.984539408169035 0.325741677960828 ANO3 other 1 1 1 1.62565901243817 -0.984539408169035 0.0217428467070491 257.530661422782 283.385726048507 0.908763701735283 0.364282332097202 -872.286279584648 514.265654404311 -1.69617837029199 0.091000452703185 IL6ST og 1 1 1 0.908763701735283 -1.69617837029199 0.0102992632228348 1066.0682793267 411.095505670618 2.59323749498946 0.0100281614080241 62.2751425555821 752.547528929646 0.0827524377684908 0.934109931945885 FST other 1 1 1 2.59323749498946 0.0827524377684908 0.167156172545819 422.411260095198 252.561170846093 1.67251069782461 0.0955692441147544 750.02001998076 695.353865060484 1.07861630986335 0.281710892769851 NAV1 other 1 1 1 1.67251069782461 1.07861630986335 4.48619628882458e-09 195.190116704362 33.611465273879 5.80724806591676 1.83312248105747e-08 -217.407819063005 92.5461726730399 -2.34918217343352 0.0195577479381022 CDC73 ts 4.6620551833465e-05 1 0.000224594166379161 5.80724806591676 -2.34918217343352 5.45063502297539e-08 197.463098688197 34.661647687752 5.69687570732456 3.154402097043e-08 -112.650543482228 94.7413260041786 -1.18903279311564 0.23545995597779 TIMM17A other 0.000530673825836884 1 0.00038225044611967 5.69687570732456 -1.18903279311564 0.0186108672387656 -16.3246131845209 18.6491036682625 -0.87535645009591 0.382152308039074 -109.575067470942 39.0476132803315 -2.80619116677575 0.00537527528123121 ERN2 other 1 1 1 -0.87535645009591 -2.80619116677575 2.40766542547094e-09 2723.21278801998 561.61796009953 4.84887055167781 2.09899091028557e-06 -1405.43686117135 1098.96471487857 -1.27887350898854 0.202039684278579 RPS15A essential 2.5480323197759e-05 1 0.0227404675220338 4.84887055167781 -1.27887350898854 1.03271434687141e-20 881.131129745717 144.15257075886 6.11248987865559 3.41849299673149e-09 -965.807197714226 242.397210051323 -3.98439898507799 8.70880755544757e-05 NARS essential 1.52315039020064e-16 1 4.3298632296601e-05 6.11248987865559 -3.98439898507799 0.305401993120157 -36.4017366029144 46.5507652661751 -0.781979337928625 0.434909399074878 -120.312010670745 77.986770337307 -1.54272333820689 0.124064794554454 GRP other 1 1 1 -0.781979337928625 -1.54272333820689 5.63699616502573e-15 252.500806570782 44.8521460640259 5.62962597620948 4.49381391888743e-08 -233.217838375778 79.6006834274391 -2.92984718640475 0.00367893480941973 KIAA1468 other 7.44703563361549e-11 1 0.000541055195834046 5.62962597620948 -2.92984718640475 5.43725416351779e-32 262.526592974132 55.8186675951613 4.70320421974547 4.08461251972305e-06 -760.893072332043 96.010655744492 -7.92508983957954 5.95501255053148e-14 FBXO18 other 8.54953844671537e-28 9.51134604570889e-10 0.0432968927090643 4.70320421974547 -7.92508983957954 8.91000974023103e-26 401.8466558873 71.4436193972997 5.62466822478045 4.62533975363947e-08 -653.099377458906 122.991728670269 -5.31010812287885 2.28494034289721e-07 RBM17 essential 1.37151779931376e-21 0.00360197995654317 0.000556705892748046 5.62466822478045 -5.31010812287885 0.419896462267844 -43.1725215579606 32.732796260597 -1.31893777770311 0.188303327664638 -44.3115994550685 56.3019034442735 -0.787035548432695 0.431948799726951 IL2RA other 1 1 1 -1.31893777770311 -0.787035548432695 2.18890201921436e-11 39.1164708605824 10.8561333258133 3.60316787631676 0.000373934401267204 -59.2517456275484 18.6730447781474 -3.17311645377134 0.00168181572190996 ANKRD16 other 2.56123425268273e-07 1 1 3.60316787631676 -3.17311645377134 5.91947936294913e-05 77.6363298202104 35.8307022693238 2.16675434482561 0.0311186181764127 -119.471013920983 60.6140870322417 -1.97101069686053 0.049732621950193 ECHDC3 other 0.450235600345911 1 1 2.16675434482561 -1.97101069686053 7.23512629516606e-07 -21.0925400775506 37.8284309248941 -0.557584323796788 0.577588538287715 -310.415119003984 65.0666276240378 -4.77072702764921 3.00331772060735e-06 IL15RA other 0.00651627491505201 0.0466805673314 1 -0.557584323796788 -4.77072702764921 6.12389019295081e-16 136.028531774301 23.8619747990636 5.70064015739548 3.0927849193577e-08 -121.483799651182 37.3889184921836 -3.24919266323735 0.00130224375934126 CCNH essential 8.29297209929398e-12 1 0.00037490738792454 5.70064015739548 -3.24919266323735 1.73670972485758e-10 85.7202878976232 17.2995625734052 4.9550552237316 1.3728321204698e-06 -104.663155775738 39.8929813588017 -2.62359824236716 0.00926299832054383 TMEM241 other 1.95206173073992e-06 1 0.0150778151791198 4.9550552237316 -2.62359824236716 7.22654645475487e-10 404.915883983343 74.5463309767738 5.43173458274562 1.30152950644236e-07 -233.732519342679 165.472550084951 -1.41251536416575 0.159017548190507 KCTD1 other 7.87043174387353e-06 1 0.00152955747597106 5.43173458274562 -1.41251536416575 0.00974321400179499 66.6342193125752 41.166128487743 1.6186661646459 0.106854726586398 -157.674031834149 90.368972714947 -1.74478061548297 0.0823247901482874 CABLES1 other 1 1 1 1.6186661646459 -1.74478061548297 0.532905189725685 -69.4769747394702 76.2176546632237 -0.911560124048188 0.362804529776863 -125.189931996989 123.52459524265 -1.01348182320345 0.311727450849543 DOCK2 other 1 1 1 -0.911560124048188 -1.01348182320345 0.343271861953356 434.018142116086 381.025381217172 1.13907934618327 0.255672240599781 -1021.77958870872 1632.26548786035 -0.625988600695171 0.531847348374794 EMP1 other 1 1 1 1.13907934618327 -0.625988600695171 0.000828571037435657 25.450456853018 7.04196469272724 3.61411310103594 0.000360338602017099 -23.5688707237562 43.8658147890033 -0.537294721119933 0.591513218754631 SOX5 other 1 1 1 3.61411310103594 -0.537294721119933 0.0113090018774895 68.3125515372707 27.1392202421057 2.51711548555422 0.0124159189243587 253.641811837783 113.022437417935 2.24417219830311 0.0256377435938462 RERG other 1 1 1 2.51711548555422 2.24417219830311 0.0869248179179808 -3.8958332643992 8.03178281485911 -0.485052117842598 0.628031233614019 74.2776250657634 36.4529894414365 2.03762781061054 0.0425584041245012 KLRD1 other 1 1 1 -0.485052117842598 2.03762781061054 0.861327678232793 -0.397878153144995 1.93489921426632 -0.205632495073323 0.837231808200297 3.95935474327117 8.65227043672352 0.457608759715388 0.647598863463346 KLRC1 other 1 1 1 -0.205632495073323 0.457608759715388 0.42697084863459 5.63253642590048 5.0860808662393 1.10744138247751 0.269118815985134 21.0991975303959 23.0348285249565 0.915969376873656 0.360525254578991 SPX other 1 1 1 1.10744138247751 0.915969376873656 0.589918689950574 -12.0582936076688 15.0880000642611 -0.799197611102295 0.424870613090286 -52.6700216588584 66.141654985593 -0.796321496193753 0.426537118890114 PRH2 other 1 1 1 -0.799197611102295 -0.796321496193753 0.00121987034522694 555.977150301861 153.445537119622 3.62328654673375 0.000348146368518361 301.282524409011 329.160328424657 0.915306306355119 0.360856745647929 LRP4 other 1 1 1 3.62328654673375 0.915306306355119 5.09177011907353e-11 178.734548589671 38.561472072836 4.63505512061553 5.56927859391161e-06 -233.214755507987 81.6821600252063 -2.8551492202951 0.00463678547721515 DDB2 ts 5.87182930131559e-07 1 0.0583716089427876 4.63505512061553 -2.8551492202951 1.5498228565922e-07 29.4292109752698 46.4084661179854 0.634134532704683 0.52653190493049 -476.157135343056 98.3039171537222 -4.8437249412805 2.15359895067662e-06 ACP2 other 0.00146551249319359 0.0335423036567883 1 0.634134532704683 -4.8437249412805 0.152582205902415 17.2476504835643 12.4641516440125 1.38378053927559 0.167572786226461 -10.1442898413299 22.2181784594287 -0.456576125709575 0.648344181619932 PIWIL4 other 1 1 1 1.38378053927559 -0.456576125709575 1.44515225187684e-07 395.251482776157 118.852265355816 3.32556961865948 0.00100514948043432 -339.550610779416 170.60786045805 -1.99024013235842 0.047576521162323 PUM1 other 0.00136957078910368 1 1 3.32556961865948 -1.99024013235842 0.152763066842029 -11.3594180574911 37.87740222208 -0.299899607446396 0.764486208357933 -95.1485179557988 53.8380314907088 -1.76731049262489 0.0783142555049201 SPOCD1 other 1 1 1 -0.299899607446396 -1.76731049262489 1.01924470786292e-14 551.078668127591 121.285294676782 4.54365609281969 8.34559036669613e-06 -619.858948137326 172.961016859162 -3.58380726127473 0.000401666902239968 YARS essential 1.33673943436222e-10 1 0.0862600220301712 4.54365609281969 -3.58380726127473 7.73280532047415e-07 173.591259947147 58.5208725656539 2.96631359610021 0.00328373538227802 -216.224176874201 89.8770336037913 -2.40577785229753 0.0168107036710758 CDCA8 essential 0.00694560573884988 1 1 2.96631359610021 -2.40577785229753 7.78697136598849e-15 277.530800698726 70.6129146908633 3.93031220866225 0.000107855636617328 -491.403133818062 108.448131893665 -4.53122728107379 8.81505617158095e-06 GNL2 essential 1.02422034376847e-10 0.135743049986175 1 3.93031220866225 -4.53122728107379 9.75035363344534e-05 97.8452182365153 45.5718667261021 2.14705311117907 0.0326763937646935 -138.93737576318 65.2465888548677 -2.12941976280518 0.0341209473819806 AGO4 other 0.723866253746982 1 1 2.14705311117907 -2.12941976280518 1.96551168237075e-07 213.034280731274 78.2802118447249 2.72143209261933 0.00692417170521034 -346.683997651224 128.350412526398 -2.70107427648448 0.00735041069981525 HOOK1 other 0.0018469913279238 1 1 2.72143209261933 -2.70107427648448 0.000100398613295694 27.3490538349697 17.0815405953408 1.60108824390403 0.110526710287195 -70.2426294283265 27.9772101369661 -2.51070886212186 0.0126337026969237 CYP2J2 other 0.744054123134388 1 1 1.60108824390403 -2.51070886212186 9.12758098098307e-11 197.169155588861 70.843492455053 2.78316537985414 0.00576466861732128 -438.058172597405 114.014805732208 -3.84211655481214 0.00015222506314516 BTF3L4 other 1.04045295602226e-06 1 1 2.78316537985414 -3.84211655481214 1.71662877691093e-12 299.260425677075 48.2276430862072 6.20516381325427 2.03763310685768e-09 -57.0452540782885 85.464555891129 -0.667472655576153 0.505038247419624 ZCCHC11 other 2.09823535401824e-08 1 2.60205747745726e-05 6.20516381325427 -0.667472655576153 5.60251849458438e-32 388.627742031506 40.5887832834513 9.57475712729619 6.9224491344594e-19 -242.827330522336 72.0002633855348 -3.3725894754313 0.00085367004180132 PRPF38A essential 8.80883982903502e-28 1 1.05269683987724e-14 9.57475712729619 -3.3725894754313 1.74895993163218e-05 888.827839430996 390.549863089566 2.27583702731233 0.023648133976643 -2101.97378895644 751.175088286728 -2.79824746817762 0.00551240769213584 DSC2 other 0.140406503311432 1 1 2.27583702731233 -2.79824746817762 0.00368571896574373 2195.51770554505 920.093076890833 2.38619087643189 0.0177236450868052 -2036.3680891285 1773.57486826749 -1.14817148436351 0.251929286511129 DSG3 other 1 1 1 2.38619087643189 -1.14817148436351 1.37792949705446e-20 283.321678236659 35.4854594938513 7.98416259160325 4.17899711229212e-14 -179.342815763559 68.8119727305603 -2.6062734237513 0.00966549897540156 RNF138 other 2.0291389773624e-16 1 6.03029283303753e-10 7.98416259160325 -2.6062734237513 7.68906436436157e-28 585.516711445639 60.2613588042105 9.71628790097459 2.81905960373047e-19 -347.980886810999 108.925250550249 -3.19467602831421 0.00156988556454732 ELP2 essential 1.19426547707264e-23 1 4.29822017780785e-15 9.71628790097459 -3.19467602831421 0.577786620096827 80.9068253567092 80.6417679073586 1.00328685067588 0.316627469880988 113.121473263786 160.329044999474 0.705558205402877 0.481075735233664 DSG1 other 1 1 1 1.00328685067588 0.705558205402877 0.0113713817420464 1905.2377385692 749.914284844022 2.54060734283183 0.0116328074502386 -528.480018585881 1447.80018162928 -0.365022760248004 0.715383385398908 DSC3 other 1 1 1 2.54060734283183 -0.365022760248004 0.379602228660942 -16.0511035979473 39.9472641447722 -0.401807331279979 0.68814726311754 -105.827847723385 76.8336965563878 -1.37736243948277 0.169553741121764 DSC1 other 1 1 1 -0.401807331279979 -1.37736243948277 1.97994901047479e-10 164.983320662642 30.1793464438134 5.46676254138904 1.05830959533789e-07 -85.8807832950478 54.5214451887127 -1.57517437400627 0.116409248769715 DTNA other 2.22090880504957e-06 1 0.00124975780113452 5.46676254138904 -1.57517437400627 0.0111888725307807 102.414625895151 73.7779912983331 1.38814603234481 0.166258456185584 -248.13346377356 133.082275445972 -1.86451173112302 0.0633553575131423 FHOD3 other 1 1 1 1.38814603234481 -1.86451173112302 4.78077793761549e-22 864.124575296705 102.928027623116 8.39542537879777 2.82807283045035e-15 -525.473580974592 185.663717352517 -2.8302437787394 0.00500740726164943 TPGS2 other 7.15921496157919e-18 1 4.15189372238416e-11 8.39542537879777 -2.8302437787394 0.429433182663609 20.5160920907819 24.1577744164608 0.849254229181083 0.396492201047178 -31.8637823849609 49.3400206886474 -0.645799939688563 0.518957393902957 DAGLA other 1 1 1 0.849254229181083 -0.645799939688563 0.419937918686736 34.6321555055823 112.297241454092 0.308397205996731 0.758017031886343 -322.478504867964 296.332568115056 -1.08823173544245 0.277459663409317 SLC43A3 other 1 1 1 0.308397205996731 -1.08823173544245 1.73799960748116e-08 181.330923309029 32.8730601065221 5.51609502496705 8.08984434351109e-08 -54.927181376078 85.4514245890996 -0.642788363566786 0.520904895908721 TIMM10 essential 0.000174477780595033 1 0.000960669015791942 5.51609502496705 -0.642788363566786 1.02900097841607e-10 192.240028998877 38.1869941801883 5.03417546015215 8.74346733067427e-07 -181.357482122633 78.4921221843247 -2.31051826700197 0.0216078610633963 DHX34 other 1.16997411245907e-06 1 0.00973618251624525 5.03417546015215 -2.31051826700197 0.839175519094389 -7.94978667861532 30.1021355165713 -0.264093777474324 0.791906909617015 -47.4683329761743 80.5136723177743 -0.58956859884399 0.5559675074123 APLNR other 1 1 1 -0.264093777474324 -0.58956859884399 1.84290685257519e-05 1806.43736198693 414.775148504267 4.35522081904178 1.88944322958551e-05 -300.000146346705 838.982230882236 -0.357576281480048 0.72093978321584 FADS2 other 0.147598409822747 1 0.189662311385793 4.35522081904178 -0.357576281480048 0.050104988893554 -115.133844421173 56.2608193913842 -2.04643028072934 0.041682457088425 -262.819472710148 129.416684117189 -2.03080054556305 0.0432550185967965 TCN1 other 1 1 1 -2.04643028072934 -2.03080054556305 0.415403667792472 4.24109951518302 9.82997683139014 0.431445525043343 0.666486213277144 -19.1053616276962 20.2051970594443 -0.945566706005769 0.345208842694856 C5AR2 other 1 1 1 0.431445525043343 -0.945566706005769 1.24413876876646e-15 892.498550532098 121.814063407883 7.3267283395978 3.21708137651252e-12 -382.155743708186 269.067997026473 -1.42029430453071 0.156762959076125 TMEM165 other 1.67162484971462e-11 1 4.48171606561959e-08 7.3267283395978 -1.42029430453071 3.64393073685461e-27 285.318221225252 30.5167495770546 9.3495613123811 5.05878468000128e-18 -238.600962848656 67.406672552762 -3.53972320265316 0.000477202195359275 CLOCK other 5.64299113909305e-23 1 7.64685892228993e-14 9.3495613123811 -3.53972320265316 0.0727688685923513 -33.3102086994193 78.225198137963 -0.425824535984828 0.670609543109229 -388.468086079483 174.147601385902 -2.23068295507934 0.0266080765250213 PDGFRA other 1 1 1 -0.425824535984828 -2.23068295507934 0.00304472882169642 21.3639659658163 14.0121945820364 1.52466951844965 0.128511991809006 -53.2145560244492 25.416483292757 -2.09370255560154 0.0372192344578565 GGACT other 1 1 1 1.52466951844965 -2.09370255560154 0.00389231221572296 2288.90861176579 913.159889220792 2.50658032485301 0.0127899270869729 -1748.86662062221 1802.52079911421 -0.97023380894225 0.332814672560718 COL4A2 other 1 1 1 2.50658032485301 -0.97023380894225 0.132677266896423 78.805587359743 54.2085326906486 1.45374876330747 0.147217344609005 -45.7837569651175 94.4178740385227 -0.484905611689982 0.628150023170425 CLDN10 other 1 1 1 1.45374876330747 -0.484905611689982 1.5827180797239e-07 114.962176991774 34.7824121291446 3.30518126704173 0.00108219370367536 -147.927735991968 60.5823704158679 -2.44176209970851 0.0152802766195059 DZIP1 other 0.00149519376991517 1 1 3.30518126704173 -2.44176209970851 1.52522804378988e-25 505.967607887574 52.5239197875471 9.63308926550325 4.44850910738118e-19 -186.020726910711 94.7602601388929 -1.96306686619533 0.050661046106439 UBAC2 other 2.34412298050067e-21 1 6.77418966872007e-15 9.63308926550325 -1.96306686619533 1.03815190957177e-11 304.810878225339 73.8029521682595 4.13006349028447 4.84984410891888e-05 -529.780743512359 135.255562325966 -3.91688692429217 0.000113889463705176 ARGLU1 other 1.23083290398829e-07 1 0.468640436244831 4.13006349028447 -3.91688692429217 2.8886202716306e-16 106.323271370466 20.6127731240727 5.15812553364286 4.83390219716904e-07 -168.147099967161 37.5111545116449 -4.48258930326877 1.09080868424605e-05 BIVM other 3.94383325685726e-12 0.167733651376515 0.00546859355565733 5.15812553364286 -4.48258930326877 1.24141067449855e-20 219.985646576356 37.6627016979404 5.84094174498337 1.48850903484314e-08 -362.676112854842 68.5386393288112 -5.2915569437397 2.51158837402136e-07 ERCC5 other 1.82921862887362e-16 0.00395750980094546 0.00018333965782163 5.84094174498337 -5.2915569437397 2.18831160670389e-27 283.730646408283 31.7768174233258 8.92885661356415 6.80404235810783e-17 -230.953393206679 57.8274985650835 -3.99383336539703 8.38791518249426e-05 TPP2 other 3.39253948387304e-23 1 1.01761257507861e-12 8.92885661356415 -3.99383336539703 2.26621541141632e-13 67.738108843995 9.96591874806856 6.79697582895937 6.82503002642871e-11 -17.6837936005976 18.135993432767 -0.975066166965391 0.330400217415115 KDELC1 other 2.85701776917256e-09 1 9.17011034350962e-07 6.79697582895937 -0.975066166965391 1.14314447595593e-20 340.492283604885 37.6716969030852 9.03841110425264 3.4358834560588e-17 -71.2635083321711 74.3615855309641 -0.958337666193213 0.338766022138911 CARS2 other 1.68510927200663e-16 1 5.15142006566895e-13 9.03841110425264 -0.958337666193213 2.24278007826997e-09 291.552627982925 77.2650301575341 3.77340987751489 0.00019796334208704 -379.58967904237 142.006962790497 -2.6730356848937 0.00797449074225476 ARHGAP32 other 2.37801971698965e-05 1 1 3.77340987751489 -2.6730356848937 1.09536737355777e-17 1078.77002730868 160.39116849633 6.72586924468573 1.02624373029094e-10 -737.482941852912 287.777996664503 -2.56268008812599 0.0109254326698245 STT3A other 1.54260587218141e-13 1 1.37095899929567e-06 6.72586924468573 -2.56268008812599 0.967265943994807 -6.48320268039851 48.685699234425 -0.133164415472015 0.894163285877178 -22.953875664104 88.9633867763399 -0.258014858649791 0.796593460422884 ADAMTS8 other 1 1 1 -0.133164415472015 -0.258014858649791 0.206164008318154 384.167738445242 232.698685243841 1.65092354536803 0.0999125345261866 595.173334288652 426.049091838542 1.39695951872655 0.163568588405023 ETS1 other 1 1 1 1.65092354536803 1.39695951872655 5.2637212927405e-06 135.262758022433 63.0230601468895 2.14624230729471 0.0327383673009196 -331.097869703214 113.642781543688 -2.91349670613202 0.0038709264257306 SLC37A2 other 0.0441205118757509 1 1 2.14624230729471 -2.91349670613202 0.223381771021675 14.3103471922486 16.6655953294005 0.858676027432584 0.39127812915212 -17.2255115912272 26.8260531235775 -0.64211874597712 0.521338883388547 KLB other 1 1 1 0.858676027432584 -0.64211874597712 4.70616821009611e-08 310.956734693878 122.33449445012 2.54185653924999 0.011579762388036 -718.686216640502 200.099829439908 -3.59163832698983 0.000389606850745326 TMED7 other 0.000460075004218995 1 1 2.54185653924999 -3.59163832698983 0.000222493905394214 83.3200720760071 41.4885134824046 2.00826843582486 0.0455996218563689 -154.970634487278 68.4042934137509 -2.26551034669595 0.024264924176507 APC ts 1 1 1 2.00826843582486 -2.26551034669595 0.401924194719067 657.943835317243 853.272106958461 0.771083256972413 0.441324432987851 -864.191944232099 1406.83458304453 -0.614281134859438 0.539541144090913 NREP other 1 1 1 0.771083256972413 -0.614281134859438 5.89973244843125e-12 232.31740959499 34.0253270495344 6.82777888532211 5.61452558607207e-11 23.1062486004705 56.0775464013892 0.412041005415637 0.680633900337164 WDR36 other 7.05136022236503e-08 1 7.56445032211491e-07 6.82777888532211 0.412041005415637 3.19775584078868e-23 390.393084092352 71.5103916165234 5.45924970157969 1.07457418249762e-07 -816.619858886077 135.039686111918 -6.04725827198145 4.8299251707344e-09 OSTF1 other 4.83660570919288e-19 7.68054700650185e-05 0.00126831990760194 5.45924970157969 -6.04725827198145 0.00947274961802483 44.878101188158 52.5990055047841 0.853211971547183 0.394295245326785 -219.055265432428 98.6554589757911 -2.22040693648977 0.0272183956836855 RFK other 1 1 1 0.853211971547183 -2.22040693648977 9.39025725197883e-37 782.151348667662 101.948502371816 7.67202391865535 3.03310376477108e-13 -1469.28530935411 188.534288488542 -7.79319942877873 1.38969521054024e-13 UBQLN1 other 1.48657162556077e-32 2.21948222075382e-09 4.32277948555174e-09 7.67202391865535 -7.79319942877873 6.0867742315866e-30 146.291165627792 17.0490849618836 8.58058751861773 7.2323089099754e-16 -159.68424357451 32.1871482365453 -4.96111809598605 1.23438029447073e-06 NAA35 essential 9.53432315635726e-26 0.0192933640025776 1.06922454925076e-11 8.58058751861773 -4.96111809598605 1.67524156987566e-19 46.3909129421732 7.47677443033034 6.20466932290794 2.02527159518814e-09 -57.3215519558622 14.1190846445893 -4.05986318509881 6.41864960538909e-05 C9orf40 other 2.43161313867452e-15 0.964594662697873 2.58647435421477e-05 6.20466932290794 -4.05986318509881 0.00159180446848541 1382.10196104414 1192.55476941633 1.15894212701072 0.247503741382191 -5580.46010713809 2269.36680656812 -2.4590383938757 0.0145586418422763 ANXA1 other 1 1 1 1.15894212701072 -2.4590383938757 0.011139425571924 373.614819381042 228.118349776992 1.63781133673063 0.102613107231684 -654.011433334123 429.58785351028 -1.5224160273388 0.129062325000773 CTSL other 1 1 1 1.63781133673063 -1.5224160273388 0.00624444846457928 49.4787416481974 138.656281872992 0.356844572635515 0.721488969262697 -693.260472003703 261.527109562763 -2.6508168624 0.00850756259259661 TMEM2 other 1 1 1 0.356844572635515 -2.6508168624 4.66746987084833e-13 83.8569172118599 20.5677456103279 4.0771078561839 5.98623817185621e-05 -161.137520353344 38.7516933705621 -4.15820590889979 4.29881674090555e-05 AGTPBP1 other 5.81893468798661e-09 0.650453961066419 0.574439414971322 4.0771078561839 -4.15820590889979 0.0179961344589687 191.683295509391 141.859060943273 1.3512234906591 0.177742553254008 -432.674611003353 267.817224999845 -1.61555930916543 0.107344667968442 GOLM1 other 1 1 1 1.3512234906591 -1.61555930916543 0.629683536842195 -38.8691016752729 42.6652603338635 -0.911024598727749 0.363107243733491 -58.4018065462304 82.5397188813765 -0.707560037006712 0.479837977021405 FAM189A2 other 1 1 1 -0.911024598727749 -0.707560037006712 9.96965234205682e-17 1115.14961184757 155.019826858244 7.19359345477345 6.17928652167467e-12 -490.416383722107 284.261729473341 -1.72522831205845 0.0856263545048847 PSAT1 other 1.37551293363358e-12 1 8.54286361621523e-08 7.19359345477345 -1.72522831205845 4.64436047610079e-21 174.122220967128 31.0717371876614 5.60387788798215 5.11968125763536e-08 -316.284385104716 58.6606620274442 -5.39176296641083 1.51125243787043e-07 ISCA1 other 6.88108448139093e-17 0.00238536084793469 0.000614771325416854 5.60387788798215 -5.39176296641083 0.631227169713314 85.5909112961909 105.304860087007 0.812791652972826 0.417048356484618 -9.58001940648525 171.837098519351 -0.0557505887205516 0.95558142729565 ADAM19 other 1 1 1 0.812791652972826 -0.0557505887205516 0.346943225719065 -14.3753194940914 46.9215010556681 -0.306369557040309 0.759556807261116 -107.975829269903 77.1824753688236 -1.39896820818367 0.162957599201315 HAVCR2 other 1 1 1 -0.306369557040309 -1.39896820818367 0.0817980569357271 22.3881563728892 38.2606803744609 0.585147889524551 0.558931612390154 -101.116935898425 62.4975053432641 -1.61793555347602 0.106831252104583 CCNJL other 1 1 1 0.585147889524551 -1.61793555347602 0.0529131220077916 71.0199993640905 40.0747306105636 1.77218906483104 0.077490870135299 -87.7115910463895 83.2644421744542 -1.05340994013528 0.293094933454546 TAOK3 other 1 1 1 1.77218906483104 -1.05340994013528 1.26793663304261e-06 35.0772523254398 13.2128801081796 2.65477715972952 0.00840558764136851 -103.289283683334 28.4259953873652 -3.63362064461758 0.000334252685953439 USP30 other 0.0112009522162985 1 1 2.65477715972952 -3.63362064461758 0.649585997389441 -9.03130041189888 21.2163125247661 -0.425677195382397 0.670680939255395 30.4461069915254 44.8181636951007 0.679325177145838 0.497511642422918 SDS other 1 1 1 -0.425677195382397 0.679325177145838 0.0368680497465066 38.2748937135759 34.9489235470963 1.09516659825009 0.274423238063486 -137.022015620522 72.9931886865537 -1.87718906498139 0.0615743595826866 MSI1 other 1 1 1 1.09516659825009 -1.87718906498139 0.0353559625795336 24.5243989572519 11.5600387451883 2.12148068858851 0.03478569657949 -17.481515039336 23.9326897007804 -0.730445063129114 0.465746854429878 HNF1A other 1 1 1 2.12148068858851 -0.730445063129114 3.51141544952174e-07 226.181362890812 55.4105399396335 4.08191948927449 5.87630477193546e-05 -295.100450300257 117.060735611937 -2.5209174430488 0.0122770950804895 FBXO21 other 0.00324764310436049 1 0.564360310296681 4.08191948927449 -2.5209174430488 0.204495863568739 -10.0518601364109 88.2380510752327 -0.113917522133853 0.909387524336799 -327.877832170058 187.694501603704 -1.74686967049432 0.0817928236448154 TBX3 other 1 1 1 -0.113917522133853 -1.74686967049432 0.821157202611561 34.3024046887419 54.6253078337216 0.62795810310411 0.53055825085397 23.8235353506589 113.090498311541 0.210659035961005 0.833311068506332 OASL other 1 1 1 0.62795810310411 0.210659035961005 0.0380861708786756 19.3957819293868 7.97681137241617 2.43152069465469 0.015681588656305 25.1948597737385 16.8518734542199 1.49507767443087 0.13605343186436 HRK other 1 1 1 2.43152069465469 1.49507767443087 0.00452392656749057 85.5504797701682 25.9595281546818 3.29553292572997 0.00111278238564396 30.8035310006634 54.8423001334491 0.561674673121084 0.574800193250159 RNFT2 other 1 1 1 3.29553292572997 0.561674673121084 0.000137293390499635 94.5041096386881 34.0440625383038 2.77593514382601 0.00588638591164425 -153.790653063655 70.481250352411 -2.18200801340344 0.0299647610048573 P2RX4 other 0.999907763008844 1 1 2.77593514382601 -2.18200801340344 0.0813860677924257 27.7898682359282 56.4762191869065 0.492063184044923 0.62307450993787 -223.180853120842 116.52473965673 -1.91530874712366 0.0565094686366337 BICDL1 other 1 1 1 0.492063184044923 -1.91530874712366 0.705425742205431 12.6952560386733 20.1355864146551 0.630488518051478 0.52890631577684 -15.1637976694915 42.5351958298797 -0.356500008372816 0.721743547736439 DTX1 other 1 1 1 0.630488518051478 -0.356500008372816 1.15357944337893e-08 223.125892380651 53.3072648813349 4.18565636179876 3.85085259726639e-05 -362.343988929184 112.744596195207 -3.21384794621837 0.00146871389103162 TRAFD1 other 0.000117042170325226 1 0.375920230545145 4.18565636179876 -3.21384794621837 2.11908199454934e-05 163.200875189034 41.9125678214652 3.89384100454594 0.000125611765839174 -190.242546771489 141.201300247383 -1.34731441168166 0.179056495195407 DMTF1 other 0.168636545126236 1 1 3.89384100454594 -1.34731441168166 0.000183382078276274 72.3191115115239 21.8853139187222 3.30445849577955 0.00108594425506249 -107.530837185524 73.7305047690989 -1.45843077464717 0.145933422889083 TMEM243 other 1 1 1 3.30445849577955 -1.45843077464717 0.0899904322363116 -11.058688821047 16.4149184481129 -0.673697457346692 0.501077859233381 -122.41444951069 55.5343304977723 -2.20430224715864 0.0283437171971108 CCDC146 other 1 1 1 -0.673697457346692 -2.20430224715864 4.32341408036535e-14 84.8401311679345 11.2045456841798 7.57193852917429 5.79802006993051e-13 -25.2495534620792 34.6954743901336 -0.727747751137809 0.467396297757782 TMEM60 other 5.5772041636713e-10 1 8.21039533206284e-09 7.57193852917429 -0.727747751137809 0.624924150205337 -102.782213592234 125.501271523075 -0.818973484052194 0.413531920454028 -289.426252427185 377.089886052779 -0.76752589536882 0.443447105989859 CD36 other 1 1 1 -0.818973484052194 -0.76752589536882 8.56232463476221e-06 102.709516464747 29.393811187806 3.49425652252117 0.000556670288488653 -225.884336817798 94.9812200514795 -2.37819999253926 0.0181040355869261 PNPLA8 other 0.0705364303411711 1 1 3.49425652252117 -2.37819999253926 4.1298588513432e-07 699.759053744971 129.088625326232 5.42076462567126 1.309297260222e-07 307.11828406313 347.566695898598 0.883624028674863 0.377679537404259 HILPDA other 0.00379699222792494 1 0.00153842428076085 5.42076462567126 0.883624028674863 0.245343960779778 5.16997993656722 3.62956200418705 1.42440876629278 0.155474444702682 -2.72586029496898 9.77247120082258 -0.2789325482729 0.78050854395276 FAM71F1 other 1 1 1 1.42440876629278 -0.2789325482729 5.11728186066404e-21 135.438592763946 13.9233054039247 9.72747410437241 2.38604089001432e-19 -78.8910787852318 52.7245067083038 -1.49628860866719 0.13575515273321 RINT1 essential 7.57767097927131e-17 1 3.63918956544984e-15 9.72747410437241 -1.49628860866719 3.54302846055548e-24 352.222886213178 32.5146239296088 10.832752886077 6.61816149252793e-23 -106.349724530146 124.626588559804 -0.853346992476755 0.394231800629836 SRPK2 other 5.39957537388655e-20 1 1.02667539233586e-18 10.832752886077 -0.853346992476755 1.32204669424358e-09 150.590468792764 27.8010999867401 5.41670901024021 1.33637059803161e-07 -110.666735739718 74.8535081252757 -1.47844421071761 0.140445985797042 KCP other 1.41921712627049e-05 1 0.00156929999326852 5.41670901024021 -1.47844421071761 8.80784127689901e-13 465.930308896684 76.3967438093677 6.0988241862679 3.78170966087831e-09 -580.515856858078 219.220042823404 -2.64809663104446 0.00858189103062064 TES other 1.0878564761098e-08 1 4.7827282081128e-05 6.0988241862679 -2.64809663104446 0.10892644789811 -23.8483053031572 40.5051147404909 -0.588772688485123 0.556515286382931 -246.979749776409 116.923843597408 -2.11231295668666 0.035595253587413 MDFIC other 1 1 1 -0.588772688485123 -2.11231295668666 3.80611064673223e-23 133.411632174222 13.3060377451595 10.0263981456655 2.87755676591424e-20 -50.598894467432 30.4847829196716 -1.65980825911609 0.0981358877753135 MTO1 other 5.75293624253577e-19 1 4.40899247673379e-16 10.0263981456655 -1.65980825911609 0.0042070612672885 19.883341797867 6.03880999456054 3.29259271541527 0.00113199443111203 5.58475942323401 13.9565175373862 0.40015422244652 0.689375333361159 ADGRB3 other 1 1 1 3.29259271541527 0.40015422244652 3.12628687321415e-11 176.775617566331 28.4800227277615 6.20700409041513 2.00792815460429e-09 -131.506974452812 66.3546538091706 -1.98188019835071 0.0484991304580766 ANKRD6 other 3.63555900486074e-07 1 2.56512821750698e-05 6.20700409041513 -1.98188019835071 5.18803685955042e-15 70.5360029875333 8.34264402710691 8.45487386952479 1.92091358175848e-15 17.3091280279151 19.2784869831226 0.897846809403064 0.370085309705171 KHDC1 other 6.86636678361498e-11 1 2.82643224419943e-11 8.45487386952479 0.897846809403064 5.21049267110929e-09 47.6824926157063 9.42432642249317 5.05951199885244 7.72928143001853e-07 -47.8482717624359 22.5275147687491 -2.12399247114523 0.0345698106475109 CEP162 other 5.39963355507055e-05 1 0.0086351532136167 5.05951199885244 -2.12399247114523 1.1652469082052e-27 1428.08835730799 138.64076648103 10.300638070285 3.18123672878305e-21 -1175.58563575649 331.283770661792 -3.54857599395247 0.000456105024441773 SYNCRIP other 1.8085797262253e-23 1 4.89751394396151e-17 10.300638070285 -3.54857599395247 3.71354997319398e-07 188.480567685589 40.3613154469671 4.66983213005642 4.74155454472333e-06 -140.445589519651 96.4438462764183 -1.45624210296548 0.146479011788981 SNX14 other 0.00342612120526877 1 0.0499759849013839 4.66983213005642 -1.45624210296548 0.860493411612833 -40.2797842281015 76.0048359335278 -0.529963438949192 0.596569610864455 -5.96072180837407 181.614465035687 -0.0328207436957336 0.973841606958292 NT5E other 1 1 1 -0.529963438949192 -0.0328207436957336 0.0112538813343364 134.915801813605 52.879101678753 2.55140116852278 0.0112746850723499 -92.3856047458691 126.399987715107 -0.730898842760153 0.465467766424605 MRAP2 other 1 1 1 2.55140116852278 -0.730898842760153 0.414366931837363 -31.1445386224561 110.93936066866 -0.280734794528651 0.779128815191833 -264.832912473951 202.038235735516 -1.31080590517845 0.191037160326488 EPHA7 other 1 1 1 -0.280734794528651 -1.31080590517845 2.81172059170631e-26 326.358621487222 30.5398207212207 10.6863306260488 1.73938344834073e-22 -173.973134548912 76.8514115680087 -2.26375978006541 0.0243768060018029 AKIRIN2 essential 4.33651666858865e-22 1 2.69273951637628e-18 10.6863306260488 -2.26375978006541 7.61706628574635e-43 327.418625388918 21.3463060317492 15.3384208444279 1.18449405908318e-38 -108.148957663598 53.7024892229335 -2.01385371941778 0.0450131096866372 ORC3 essential 1.2103518328051e-38 1 1.88085811641818e-34 15.3384208444279 -2.01385371941778 0.00064398670740997 34.5233575513991 10.054083420905 3.43376478054839 0.000689512178417753 -14.3422631009429 23.3660939134318 -0.613806618858894 0.539863767569262 LCA5 other 1 1 1 3.43376478054839 -0.613806618858894 1.18311010702823e-13 238.376526328774 43.6104063280841 5.46604690026162 1.04690688471772e-07 -347.121440751909 85.8770611873844 -4.04207405274951 6.91524229430834e-05 MAP3K7 other 1.50515267816131e-09 1 0.00123650172154009 5.46604690026162 -4.04207405274951 0.777395934512114 -1.22452916974806 5.13190494689082 -0.238611038672871 0.811586217777885 7.75205091225849 13.6260209490047 0.568915235142417 0.569881396991334 CGA other 1 1 1 -0.238611038672871 0.568915235142417 0.00752414377314975 114.790381202809 38.4726007722356 2.98369174162121 0.00311460555601374 33.6247205256477 85.3655553324394 0.393890959822177 0.693979500127071 PRR5L other 1 1 1 2.98369174162121 0.393890959822177 0.205815775182753 48.5299543612882 43.2089333691752 1.12314631668064 0.262380475682989 -73.3595415410115 98.867751320467 -0.741996662827155 0.458739130110586 LMO2 other 1 1 1 1.12314631668064 -0.741996662827155 5.58385790324295e-09 201.347130385001 45.8629400984723 4.39019238523933 1.63539296323231e-05 -206.443437813081 97.7543818353656 -2.11185865980684 0.035631046686447 PHF21A other 5.77705938669516e-05 1 0.164945734271611 4.39019238523933 -2.11185865980684 5.62631671251927e-23 718.718087197871 86.7477589845922 8.28514875324361 5.63008246480964e-15 -628.560976350181 198.257200974793 -3.17043201084079 0.00169820471197384 NAT10 essential 8.49292507754784e-19 1 8.23343259653762e-11 8.28514875324361 -3.17043201084079 0.176021817802446 16.7983459948067 162.799152368754 0.103184480695311 0.917893154295524 -608.922056114862 373.418907027718 -1.63066744788491 0.104126426467487 EHF other 1 1 1 0.103184480695311 -1.63066744788491 0.593161276062583 -24.7772690546729 27.9475027924878 -0.886564686607097 0.376105216779091 -54.7600323188799 64.4740796141871 -0.849334067993897 0.396450660253009 ELF5 other 1 1 1 -0.886564686607097 -0.849334067993897 1.44585501090579e-06 527.763392744917 132.272588620818 3.98996797634196 8.55738119577505e-05 -400.98439699653 296.139529543478 -1.35403874523161 0.176877573128046 PRRG4 other 0.0127105114008728 1 0.807816784881165 3.98996797634196 -1.35403874523161 9.32876764886891e-21 1727.04307482433 222.563951206746 7.75976102805628 1.77636969898913e-13 -1469.1372194052 509.037695454831 -2.88610692788185 0.00421670683705129 CAPRIN1 other 1.37711268032603e-16 1 2.53967575864476e-09 7.75976102805628 -2.88610692788185 5.52436993502681e-08 931.332659595461 198.143080494357 4.70030372633671 4.12521200814325e-06 -1035.3207194497 536.431077196355 -1.93001629372553 0.0546407061175523 ATP5G2 other 0.000537554583999849 1 0.0436942455902533 4.70030372633671 -1.93001629372553 1.15157373894166e-12 227.359218173721 43.3728502463425 5.24197088460639 3.19264749455743e-07 -431.065412437057 116.088934251771 -3.71323429933616 0.000248237775186049 DNAJC14 other 1.4153992825332e-08 1 0.00366196667625737 5.24197088460639 -3.71323429933616 0.451330094094834 -297.37153791981 476.908699918724 -0.623539763419055 0.533452407293638 -1578.65324936214 1269.5697414385 -1.24345532020433 0.214770760146957 CD63 other 1 1 1 -0.623539763419055 -1.24345532020433 0.855528834237374 -10.2226857593866 32.2060711664002 -0.31741486586702 0.751172347835092 -44.7039406922991 82.6440452381453 -0.540921497289746 0.589004397813634 PRPH other 1 1 1 -0.31741486586702 -0.540921497289746 0.150321226681559 20.9963341853269 23.5994087175487 0.889697468128251 0.374414554429789 -81.7055042253177 61.1738964062986 -1.33562694262034 0.182787769091883 AVIL other 1 1 1 0.889697468128251 -1.33562694262034 3.08233533458251e-07 134.967243728136 30.8553714741213 4.37418955857766 1.73800715905376e-05 -155.120433921748 82.1395080254667 -1.88849967148153 0.0600228962697033 GDF11 other 0.00286225659169332 1 0.174930420558761 4.37418955857766 -1.88849967148153 1.23923941798117e-07 126.130369389965 25.0877998382451 5.02755802434636 9.00533170625436e-07 -71.0254482011792 66.2707551424904 -1.07174647472276 0.284780450169062 GLS2 other 0.00117963200197628 1 0.0100166304568667 5.02755802434636 -1.07174647472276 0.240235091975149 2.77861158894892 23.2959261704961 0.119274570524179 0.905145873940885 -96.3287085676026 62.0156498925003 -1.55329676838962 0.121514989345075 ITGA7 other 1 1 1 0.119274570524179 -1.55329676838962 0.298775416261457 -10.2553425434289 6.5867282615775 -1.55697064402241 0.120640193588925 -8.09619552882643 17.8087316906118 -0.45461943441455 0.649745654940845 TESPA1 other 1 1 1 -1.55697064402241 -0.45461943441455 0.000468900274963329 5.73547366322821 1.81096761843558 3.16707687362342 0.00171452027931056 -5.39500174415708 4.65043730425235 -1.16010632789822 0.247019058533427 FAM186B other 1 1 1 3.16707687362342 -1.16010632789822 0.015058697930079 1.61812634933092 4.45370438810925 0.363321452957472 0.716646973370886 -30.9554807370379 11.8561232567554 -2.6109277093927 0.00953065954552903 RDH5 other 1 1 1 0.363321452957472 -2.6109277093927 4.13430554273238e-05 47.6698201063009 15.1294521281374 3.15079618895425 0.00180941390042929 -84.3757751101623 40.5193829103871 -2.08235587636584 0.0382410673309435 AGAP2 other 0.319292417065221 1 1 3.15079618895425 -2.08235587636584 0.00134886567995116 116.923617765565 48.7505601079079 2.39840562870987 0.01714048931357 -238.1128877703 129.777955406824 -1.83477145270066 0.06763160650214 BLOC1S1 other 1 1 1 2.39840562870987 -1.83477145270066 0.584824504608418 11.9330863229793 11.5093743656392 1.03681450823296 0.300743161668814 10.5057730365542 31.0071698861978 0.338817540430565 0.735008598757883 KRT85 other 1 1 1 1.03681450823296 0.338817540430565 1.96045660603861e-10 1151.14933221279 194.522170263467 5.91783101460173 9.75174332473955e-09 -782.443218211967 520.965216368038 -1.5019106720154 0.134275940741323 CDK4 essential 2.19963231197532e-06 1 0.000121145907323239 5.91783101460173 -1.5019106720154 0.551001664497331 9.41598751301946 13.6773427782927 0.688436903691815 0.491762277287416 -21.4961383559784 36.9876226488866 -0.581171127434583 0.56160462528384 PPP1R1A other 1 1 1 0.688436903691815 -0.581171127434583 4.33680953913328e-10 304.014047055285 48.5132952811723 6.26661300357535 1.43896211764451e-09 -51.2933062727858 124.490036339842 -0.412027402199174 0.68064385881473 TROAP other 4.77959779307879e-06 1 1.84921021738496e-05 6.26661300357535 -0.412027402199174 7.24331110614482e-10 539.947712715215 100.627436209375 5.36581009171047 1.72156652134212e-07 -557.780215100169 269.498299378286 -2.06969845964493 0.0394211858795433 TSPAN31 other 7.8872414634811e-06 1 0.00200717440723278 5.36581009171047 -2.06969845964493 2.42987314188978e-05 427.742697496935 99.3092842419393 4.30717732749799 2.30878667758655e-05 -91.0859151410532 265.96805229133 -0.342469384410431 0.732261201735472 B4GALNT1 other 0.192202965523482 1 0.230139856021828 4.30717732749799 -0.342469384410431 1.21741375117824e-10 186.255429063426 42.2424823310529 4.40919706384081 1.49540726459534e-05 -376.284058592062 105.631063867095 -3.56224811922279 0.000434000799998502 TFCP2 other 1.37920803870983e-06 1 0.151350955743009 4.40919706384081 -3.56224811922279 0.0265464302952676 29.7493044090651 12.4741046402001 2.38488494903213 0.0177697637878236 -14.1064542757197 33.2070809474319 -0.424802598519597 0.671316421504471 COQ10A other 1 1 1 2.38488494903213 -0.424802598519597 0.541116578085317 -4.74303261116296 7.49786586215633 -0.632584351115465 0.527534575699566 -20.5492028487478 19.140537028772 -1.07359594027368 0.283951848781599 FAIM2 other 1 1 1 -0.632584351115465 -1.07359594027368 2.68524559042776e-07 196.946012330143 51.342281950242 3.83594193419396 0.000155530872069186 -361.677810071927 136.677329710151 -2.64621653670678 0.00861392547399477 PAN2 other 0.00250076921836537 1 1 3.83594193419396 -2.64621653670678 6.54604463977625e-06 196.373801122982 42.0936611715454 4.66516324922877 4.83470228182594e-06 -10.7901506264161 113.311058680323 -0.0952259272138446 0.924205235713682 ESPL1 essential 0.0543714467779815 1 0.0509335885390363 4.66516324922877 -0.0952259272138446 0.942507442453705 382.084505074252 1229.89680567248 0.31066387302741 0.756293219264337 797.297230347709 3210.21542976464 0.248362531360135 0.804040642986678 KRT7 other 1 1 1 0.31066387302741 0.248362531360135 5.1248911552072e-06 32.0240830321991 8.66205602437801 3.6970533256853 0.000263785972412088 -46.4118071510214 23.0590975360054 -2.0127330255901 0.0451280838989022 ZC3H10 other 0.0430080865744988 1 1 3.6970533256853 -2.0127330255901 2.04980815977545e-08 1008.79316495933 205.888887007356 4.89969701435748 1.65366297064662e-06 -1086.35538139417 564.79916016614 -1.92343660899675 0.0554727888477921 HNRNPA1 other 0.000204898823651154 1 0.0180546923135198 4.89969701435748 -1.92343660899675 4.89185807780339e-05 169.060793621951 39.6578863922975 4.26298043091844 2.78136428787505e-05 -5.01599339026936 106.210923603614 -0.0472267184963889 0.962367062338947 SLC26A10 other 0.375009840244408 1 0.275410691785387 4.26298043091844 -0.0472267184963889 1.00755816272444e-07 277.970671220903 67.8862411963075 4.0946540318397 5.57481612625528e-05 -428.553579150062 175.2590706569 -2.44525762657404 0.015107031967773 ACVR1B other 0.000965341475706282 1 0.53635305950702 4.0946540318397 -2.44525762657404 1.52558816649532e-05 843.031413255807 284.944686129997 2.95857917094548 0.00336150193273 -1974.92999023305 763.13291107937 -2.58792401894936 0.0101724997978394 OS9 other 0.123069197391178 1 1 2.95857917094548 -2.58792401894936 1.51722110949072e-06 7.95039602686923 1.71575953798081 4.63374724189245 5.56733959518882e-06 -4.0712385054014 4.53226990641009 -0.898278034951835 0.369828889701002 MIP other 0.0133181668991096 1 0.0583624209763644 4.63374724189245 -0.898278034951835 0.506910962476655 27.3917225723814 41.4451928239954 0.660914347502384 0.509226631444586 -71.4807680113628 105.723442763531 -0.676110861913969 0.499544730146275 KCNH3 other 1 1 1 0.660914347502384 -0.676110861913969 1.78093380319633e-14 187.176205374831 32.76479435324 5.71272333825352 2.90283354734275e-08 -226.987129916795 57.8119963591167 -3.92629807327178 0.000109293625794579 LTV1 essential 2.31877581176162e-10 1 0.000352287879305516 5.71272333825352 -3.92629807327178 2.65870241335336e-06 198.957281537919 66.8951974364546 2.97416390357339 0.00320250216982825 -385.242862318551 122.27183823393 -3.15070802797213 0.00181131803312889 MAP7 other 0.0228276189210519 1 1 2.97416390357339 -3.15070802797213 2.08802178034781e-06 944.688838341545 346.17873633627 2.72890486671572 0.00677182711614719 -1838.2206923803 607.077819780058 -3.0279819695048 0.0027000895083663 CD164 other 0.0181094129009566 1 1 2.72890486671572 -3.0279819695048 1.88109207421536e-08 16.539759208147 3.80996322719306 4.34118604875156 2.00830863632685e-05 -15.6194917673932 6.64352257124508 -2.35108582832223 0.0194406783398193 AFG1L other 0.000188485425836379 1 0.201011611409955 4.34118604875156 -2.35108582832223 3.67124163003417e-07 257.843824491565 61.6210648798485 4.18434548306363 3.86761900135993e-05 -255.922267014968 112.631715960605 -2.27220427951646 0.0238578670209987 NHSL1 other 0.00338900357896152 1 0.377518290722743 4.18434548306363 -2.27220427951646 5.47858682527053e-05 65.7121001538664 23.1135026949632 2.84301782473611 0.00480896911192004 -104.598069984755 42.2471353825159 -2.47586183152297 0.0139028349028939 AHI1 other 0.417961388899889 1 1 2.84301782473611 -2.47586183152297 0.172073612926574 27.1793182084708 20.3565970157431 1.33516020322313 0.182948515218976 -29.526290951787 37.8730228945039 -0.77961273474349 0.436301688270668 HEY2 other 1 1 1 1.33516020322313 -0.77961273474349 0.383378650544919 12.9093590750516 47.7061141431868 0.270601773104072 0.786905613665942 -100.419779356701 85.4929356131332 -1.17459739376729 0.241198440238325 PKIB other 1 1 1 0.270601773104072 -1.17459739376729 5.95020423770334e-13 73.6633321799798 15.7203149834957 4.68586871556433 4.42490083782184e-06 -110.226412737931 27.5679975247414 -3.99834672935553 8.2384055838355e-05 SMPD2 other 7.39610386746525e-09 1 0.0467446524507499 4.68586871556433 -3.99834672935553 0.355772522125976 73.9967170388447 81.5191062400887 0.907722378860618 0.364834365265052 -95.42809219726 142.956328890692 -0.667533175605164 0.505001765661948 MICAL1 other 1 1 1 0.907722378860618 -0.667533175605164 3.00243869039739e-13 462.138657617175 70.0871585900533 6.59377076933977 2.23460039339693e-10 -300.442623502638 128.106142829451 -2.34526320804632 0.0197352146754165 REPS1 other 3.76746006871064e-09 1 2.95324787991338e-06 6.59377076933977 -2.34526320804632 0.688448172582274 -3.63694114646666 32.1061799783835 -0.113278538552869 0.909892987262231 -47.8831044863124 56.6499011104554 -0.845246038346128 0.398713656385381 STX11 other 1 1 1 -0.113278538552869 -0.845246038346128 0.0054005844405118 12.0477640774147 6.44428948359424 1.86952558665865 0.0627048283747402 -10.4878282172313 10.6041806682904 -0.989027681185495 0.323594525400077 TEC other 1 1 1 1.86952558665865 -0.989027681185495 0.0588633714327851 47.686459813084 20.2997642066971 2.34911397627722 0.019533771269864 -23.6614778816199 86.7053991904145 -0.272895091915288 0.785140930094957 PRADC1 other 1 1 1 2.34911397627722 -0.272895091915288 2.1297746594763e-11 190.647015022762 26.28070627139 7.25425766925853 4.283341121998e-12 171.57221375988 114.505048807366 1.49838121154395 0.135202450823257 SEMA4F other 2.49332719384891e-07 1 5.94784748200642e-08 7.25425766925853 1.49838121154395 5.63648397982178e-14 1686.21086271479 206.674298606077 8.15878352599963 1.26217542458716e-14 1752.960772539 885.446142243994 1.9797486136158 0.0487396862964966 CCT7 essential 7.24344556246897e-10 1 1.83659146031678e-10 8.15878352599963 1.9797486136158 0.000114254626355003 168.463546233223 41.0521572248644 4.10364661984653 5.37984033881129e-05 288.159453849209 180.300521669517 1.59821752694312 0.111155557309947 RAB11FIP5 other 0.840799795346465 1 0.518293818241079 4.10364661984653 1.59821752694312 1.70623315196894e-10 213.118235514018 31.1964855426572 6.83148219444805 5.4921801776231e-11 268.845064174455 133.248037010288 2.01762870363109 0.0446118695305312 SMYD5 other 1.91900042601946e-06 1 7.40126200736489e-07 6.83148219444805 2.01762870363109 0.55659758094629 35.660865917343 42.4868580020947 0.839338741301719 0.402013631951718 138.33939033236 189.585652897338 0.729693350832152 0.466203268948693 DYSF other 1 1 1 0.839338741301719 0.729693350832152 1.1949140338892e-09 194.72795646034 30.3837288188148 6.40895518853358 6.53333308786179e-10 -195.935070189795 130.474949396095 -1.50170642791342 0.134345855782316 CCDC142 other 1.28513004344783e-05 1 8.49725301407305e-06 6.40895518853358 -1.50170642791342 0.805376537980987 -2.1646320901059 6.74869207009463 -0.320748386149962 0.748647366010888 16.5287811489336 29.6401646851339 0.557648087469083 0.577543357481784 EMX1 other 1 1 1 -0.320748386149962 0.557648087469083 0.0730162118779487 24.3821255905439 13.392115134795 1.82063291310833 0.0697778286216618 -53.1933996948473 55.1652681666202 -0.964255254486987 0.335787229992473 KCNMB4 other 1 1 1 1.82063291310833 -0.964255254486987 4.97641914809338e-06 811.444727073175 166.849535088401 4.86333226306714 1.96273991720113e-06 79.4445967186747 491.847809600982 0.161522721394501 0.871802516464773 GNS other 0.0418118736822806 1 0.0213212437205559 4.86333226306714 0.161522721394501 0.171131529061127 193.901941678309 107.738144086679 1.79975201282759 0.0730161081530623 423.396924705218 455.412130663958 0.929700585902127 0.35335658102079 CPM other 1 1 1 1.79975201282759 0.929700585902127 9.59157619301989e-34 746.83442589049 54.595667581675 13.6793716236408 1.01599903343577e-32 -262.296894994406 230.777404875179 -1.13657961937944 0.256721812685678 MDM2 og 1.51287931292503e-29 1 1.6073104708954e-28 13.6793716236408 -1.13657961937944 2.05714042786773e-18 148.018156412421 47.5991877778301 3.10967819668054 0.00207109477122808 -448.573618136389 79.4047934299228 -5.64920074418768 4.04630102423442e-08 KLHL36 other 2.9363622467384e-14 0.000641136397289944 1 3.10967819668054 -5.64920074418768 0.0216139969762116 1.32047925896095 3.8129301726802 0.346316139860688 0.729371899830649 -13.0134427148085 6.38283648897086 -2.03881812377536 0.0424314313650249 BCO1 other 1 1 1 0.346316139860688 -2.03881812377536 8.03635772256434e-11 176.610288556762 36.4882682681244 4.84019376471879 2.17324312871376e-06 -83.5950533500773 61.1709952640975 -1.36657991241056 0.172881446756162 MPHOSPH6 other 9.18234233380201e-07 1 0.0235079709232968 4.84019376471879 -1.36657991241056 6.35146961386416e-07 -89.174444723697 40.6544031410859 -2.19347568366035 0.0291164439571822 -363.06747702275 67.715366500836 -5.36167041225816 1.75764394426836e-07 KIAA0513 other 0.00574553941270152 0.00277250755768891 1 -2.19347568366035 -5.36167041225816 8.59274800994404e-12 300.559058802502 106.348114951613 2.82618134735394 0.00506268374974607 -783.53698994862 185.210965867636 -4.23051079226371 3.19667731828668e-05 DYNC1LI2 other 1.02184959334255e-07 0.485287583689101 1 2.82618134735394 -4.23051079226371 0.00157174639339884 27.1359057980246 12.6021428595528 2.153277113301 0.0321858244694907 -27.5916498934156 21.9714906569323 -1.25579326065025 0.210280584346762 FBXL8 other 1 1 1 2.153277113301 -1.25579326065025 0.000690910210868771 88.0680706446125 57.3548574760391 1.53549454257478 0.125833367554645 -211.342334496243 99.8865711458167 -2.11582329908713 0.0352753437044939 FHOD1 other 1 1 1 1.53549454257478 -2.11582329908713 6.86512304661674e-05 53.3967342629033 13.3484076656992 4.00023250714125 8.1545273801223e-05 17.9613445237867 23.3398663801486 0.769556441808228 0.442228381261883 CCDC102A other 0.518797348632827 1 0.772154314257551 4.00023250714125 0.769556441808228 0.000242189021885142 27.1784452654315 8.26364079463448 3.28891900566131 0.00113924517200874 -4.2056974671741 14.3915751948571 -0.292233296927567 0.770332682372617 SLC9A5 other 1 1 1 3.28891900566131 -0.292233296927567 0.805723131760918 -4.08489298158288 7.81979995139626 -0.522378194707334 0.601832217612791 -10.1052596648415 22.0322606222324 -0.458657413240857 0.646846466851753 AGT other 1 1 1 -0.522378194707334 -0.458657413240857 3.38644296290723e-07 19.8154237912876 3.53100594420303 5.61183529691283 4.95878787162554e-08 7.78082067326912 9.59436577396959 0.810978115341319 0.418092521485242 ZNF670-ZNF695 other 0.00313618482794838 1 0.00059604630216939 5.61183529691283 0.810978115341319 3.87019289707428e-05 101.165895120607 22.0304493273886 4.59209404298605 6.71492636315805e-06 38.8320191614735 60.1185432058889 0.645924154024904 0.518873035360595 PCNX2 other 0.299707737949432 1 0.0699493879250174 4.59209404298605 0.645924154024904 0.00984279948062148 202.414176464932 66.1885517123493 3.05814481852706 0.00244995776334766 25.8611246085271 179.939212694525 0.143721450267933 0.885827244707848 KCNK1 other 1 1 1 3.05814481852706 0.143721450267933 9.22639373816157e-07 116.373238274747 21.8262938369014 5.33179105643655 2.05122212967691e-07 -17.0526755225806 61.5067489440353 -0.277248851798308 0.781800398258429 URB2 essential 0.00823178849318776 1 0.00238064840370302 5.33179105643655 -0.277248851798308 0.00204942015807457 291.002704763598 82.2645430816565 3.53740133795851 0.000475226645518726 182.748843380168 233.688948947236 0.782017481799836 0.434887020412254 EGLN1 other 1 1 1 3.53740133795851 0.782017481799836 0.898813844619836 0.50180189148829 6.52798241429094 0.0768693693766323 0.938783976863988 8.48756595321054 18.3925689637786 0.461467126746977 0.644832320661364 CAPN9 other 1 1 1 0.0768693693766323 0.461467126746977 1.40530997256599e-14 178.396077650572 21.0397994642502 8.47898184360996 1.46586780681767e-15 59.9906022896962 59.279565732765 1.0119946316769 0.312439989481238 COG2 other 1.83533482417118e-10 1 2.15907669266174e-11 8.47898184360996 1.0119946316769 1.9299461642387e-08 115.472607328378 18.7820094914666 6.14804328476362 2.79753520598876e-09 17.4544022091456 52.9279203830294 0.329776837684749 0.741823350054345 ABCB10 other 0.000193226209963579 1 3.55454823272931e-05 6.14804328476362 0.329776837684749 3.12836533711493e-09 235.824697952435 37.9627972890389 6.21199476310788 1.95285887679056e-09 -116.924965026071 103.596074465905 -1.12866211995854 0.26003487862177 NTPCR other 3.28447076743697e-05 1 2.4969253598644e-05 6.21199476310788 -1.12866211995854 2.30790539308755e-12 162.567842983347 21.6419438232709 7.51170247510498 8.49383939242838e-13 -47.5317727159857 60.9872484694733 -0.779372309930942 0.436440502213074 TAF5L other 2.80548979583722e-08 1 1.19814098469595e-08 7.51170247510498 -0.779372309930942 0.601210492967097 -978.214539275754 1055.79333114924 -0.926520854427978 0.355002794204106 -1552.15547234067 3289.83294951219 -0.471803734767391 0.637447934392315 GLUL other 1 1 1 -0.926520854427978 -0.471803734767391 5.29737189414894e-05 235.322653849522 65.4886265274391 3.59333622229692 0.000388144477491695 -499.440838545582 203.370577712472 -2.45581658941687 0.0146892202286343 STX6 other 0.404666238994037 1 1 3.59333622229692 -2.45581658941687 0.0889124027281626 33.6249761432641 16.097762840606 2.08879808183323 0.0376589656315792 44.1044360536434 50.2027358738605 0.87852654414015 0.380436294665125 RNASEL other 1 1 1 2.08879808183323 0.87852654414015 1.46914880863151e-06 678.873379646017 129.423544986443 5.24536226941651 3.14739631816697e-07 -181.23766953963 403.622298896315 -0.449027890766232 0.653770403437618 DHX9 essential 0.0129050031350192 1 0.00361100779583297 5.24536226941651 -0.449027890766232 0.000134438153321321 37.0079816738068 9.23197018757647 4.00867647120532 7.91301160254227e-05 -35.0553927614822 28.6692699179618 -1.22275149879277 0.222493761709298 KIAA1614 other 0.980726328479038 1 0.750390890269083 4.00867647120532 -1.22275149879277 5.31667939197585e-07 226.741117231782 42.4727557999869 5.33850730806244 1.99404363811055e-07 -114.408098743002 128.565407044291 -0.8898824448445 0.374324152650905 CEP350 other 0.00484562159784679 1 0.00231608168566541 5.33850730806244 -0.8898824448445 0.975985248992226 -21.3455700841459 112.606376082697 -0.189559160206612 0.849796490855783 34.3708308953915 351.176011981761 0.0978735156237737 0.922105079656863 NPL other 1 1 1 -0.189559160206612 0.0978735156237737 0.752886617215591 21.6821571807804 100.870871052963 0.214949637635191 0.82996765740456 -220.498617927308 310.026982586256 -0.711223958920932 0.477554927391958 FAM129A other 1 1 1 0.214949637635191 -0.711223958920932 9.34707294752906e-16 238.045467719475 27.4170077292012 8.68240145207161 3.80527179869638e-16 -100.887401652729 88.9029328211633 -1.13480397610361 0.257467629207674 PIGC other 1.26007890405639e-11 1 5.64930651234465e-12 8.68240145207161 -1.13480397610361 0.00259877751195259 1100.81519315844 316.287818612896 3.48042235071255 0.000582942182844944 -16.1525805915331 976.0722957791 -0.0165485493865391 0.986808902502728 LAMC1 other 1 1 1 3.48042235071255 -0.0165485493865391 0.000684950148105213 69.4854782377766 17.9885781520537 3.86275544684134 0.000140653106152806 37.139362587677 58.2765882801707 0.637294729902954 0.524476927436834 RC3H1 other 1 1 1 3.86275544684134 0.637294729902954 0.120524441730736 -5.06446948127485 5.54115787518261 -0.913973143403346 0.361537454919843 -17.6622598703026 8.59787207926691 -2.05425943855268 0.0409026066742143 GPR55 other 1 1 1 -0.913973143403346 -2.05425943855268 3.77113915392376e-05 41.6625528684521 41.1026357209065 1.01362241466332 0.311663754072947 -208.243815746665 63.9932083338369 -3.25415495126152 0.00128109468892264 SP110 other 0.292451841386787 1 1 1.01362241466332 -3.25415495126152 4.05240490043006e-15 124.420382889418 26.8756488056998 4.62948387921451 5.68332781628798e-06 -144.737862434476 39.4191653491283 -3.67176375127581 0.000289937304096428 MRPL44 other 5.37875702434081e-11 1 0.0595271755478003 4.62948387921451 -3.67176375127581 0.362980916649781 4.86949519638041 11.123252160776 0.437776212028325 0.661895941140112 -14.9223169673249 16.4726879713704 -0.905882330391975 0.365799880775062 PAX3 other 1 1 1 0.437776212028325 -0.905882330391975 0.442828900171814 -5.52700431026989 49.8343151296372 -0.110907600433399 0.911771711782439 -84.8935775472328 74.9358008410279 -1.13288410338511 0.258264224427145 DOCK10 other 1 1 1 -0.110907600433399 -1.13288410338511 0.00271924576892521 218.096599298733 122.854168983895 1.77524784956483 0.0769834600065059 -281.919256754461 182.853154395189 -1.54177956451966 0.124298342580398 TTLL4 other 1 1 1 1.77524784956483 -1.54177956451966 1.0405670905859e-08 150.363378676802 34.7282798897253 4.3297099411275 2.10606675416659e-05 -73.8681370090262 51.7755265041078 -1.42669987147626 0.154821748567384 USP37 other 0.000105929729821645 1 0.210522432746492 4.3297099411275 -1.42669987147626 0.0164721131545475 -8.96667587873485 8.18149457054442 -1.09597040020258 0.274057601874444 -36.1148455693165 12.6947192841784 -2.84487153759492 0.00477936455400994 HTR2B other 1 1 1 -1.09597040020258 -2.84487153759492 0.000291288058063479 430.98949824221 277.267760926306 1.55441619610713 0.12124365628668 -1024.50728235418 430.219241871101 -2.38136090310236 0.0179345492592181 ITM2C other 1 1 1 1.55441619610713 -2.38136090310236 0.612207394550841 18.4405280301731 19.8902182254268 0.927115420312458 0.354685514681741 23.8119549688553 29.9807730287564 0.794240860501354 0.427745086088896 SLC19A3 other 1 1 1 0.927115420312458 0.794240860501354 0.0551675813982141 578.036474351539 333.173425308136 1.7349417163657 0.0838838600835742 -237.414459177159 488.673536296973 -0.485834491829078 0.627475656308392 SERPINE2 other 1 1 1 1.7349417163657 -0.485834491829078 1.05487000450304e-13 -232.851353655474 136.703080100156 -1.70333655602254 0.089655780110582 -1550.89864246941 202.825869582059 -7.6464538062387 3.63961373230213e-13 DNAJB2 other 1.34358792473552e-09 5.81137124636682e-09 1 -1.70333655602254 -7.6464538062387 0.0195077523909343 -30.3361405706031 120.791626994976 -0.251144399039055 0.801893497368803 -448.49853210611 179.218103685286 -2.50252916911614 0.0129224729717333 WNT10A other 1 1 1 -0.251144399039055 -2.50252916911614 0.289021461536451 -58.546015868416 164.530857540176 -0.355836082931251 0.722241184495405 -363.584345067869 244.883723079114 -1.48472238373478 0.138783907781275 CYP27A1 other 1 1 1 -0.355836082931251 -1.48472238373478 2.54664341116954e-16 237.172336255115 51.2534380459685 4.62744247600324 5.72672816315612e-06 -324.909994306233 78.3694670077327 -4.1458747483146 4.52229671356471e-05 EIF4E2 other 3.48126154306876e-12 0.683771263090984 0.0599531171400814 4.62744247600324 -4.1458747483146 9.64205542588174e-06 18.5273759102275 18.4242925904072 1.00559496758502 0.315500910688308 -101.014548640791 28.587835685531 -3.53348010503353 0.000481460366179595 ARMC9 other 0.0791419909356373 1 1 1.00559496758502 -3.53348010503353 1.12820235844958e-09 106.123576618586 97.743841405517 1.08573159283053 0.278559058459345 -759.031883743629 152.178610853203 -4.98776982841446 1.09031318645179e-06 CAB39 other 1.21496111981435e-05 0.0170612207415977 1 1.08573159283053 -4.98776982841446 1.21498331575798e-05 630.422567206215 135.830041132025 4.64126022455852 5.43394391172564e-06 -431.744026812634 617.51571994829 -0.699162811351244 0.485058893249617 COX5B essential 0.0988024432374392 1 0.0570292413535606 4.64126022455852 -0.699162811351244 0.000478990724006588 138.768255757771 36.789421927499 3.77196075630765 0.000198766798694319 -92.7418585923661 156.714410699543 -0.591788962982945 0.55448345824244 REV1 other 1 1 1 3.77196075630765 -0.591788962982945 0.142920533717469 10.5996923601892 5.38636087626384 1.96787638327373 0.0500980061084583 2.55950191141899 23.0283982722535 0.111145459669372 0.911582969551603 TSGA10 other 1 1 1 1.96787638327373 0.111145459669372 3.20155481776017e-11 96.0621003841859 14.3398839477908 6.69894545408681 1.20228911069628e-10 -82.1229019705043 52.5034322334351 -1.56414349456962 0.118946539109846 MFSD9 other 3.72212763112797e-07 1 1.6036132158467e-06 6.69894545408681 -1.56414349456962 1.81114239562529e-06 365.938423086328 73.2176365240127 4.99795459754173 1.06093160052415e-06 -292.460181824306 328.419213199334 -0.890508746352782 0.374009768091771 TMEM127 other 0.0158112731138088 1 0.0117434518862019 4.99795459754173 -0.890508746352782 0.583606724334426 -16.5879985130901 16.2472884389383 -1.02097027300477 0.308179073427277 -4.02066804736875 53.1384462318768 -0.075664012263814 0.939742233637432 EDAR other 1 1 1 -1.02097027300477 -0.075664012263814 0.00010362258478803 108.378024583552 26.4009191667282 4.10508527749048 5.34841836721665e-05 -44.162414753712 92.7437668316178 -0.476176634424302 0.634330799765118 TGFBRAP1 other 0.766599882261848 1 0.515320109681324 4.10508527749048 -0.476176634424302 0.00367496692706818 91.0987867159768 29.240696816221 3.11547933650611 0.00203365749851736 -52.5902121625003 102.084737068789 -0.515162341330837 0.606859533159684 GCC2 other 1 1 1 3.11547933650611 -0.515162341330837 6.37752067884239e-11 144.32921651488 20.8127214843397 6.93466333191835 2.9632381721898e-11 -9.7896484128302 73.1129918729345 -0.133897521658585 0.893582625946533 MRPS9 essential 7.32139373931106e-07 1 4.02141052347878e-07 6.93466333191835 -0.133897521658585 3.4990286312632e-10 120.395771065183 18.8669844207715 6.38129381888046 7.53256636081501e-10 -67.7565262321145 66.2899587331176 -1.0221235240906 0.307630647884571 C2orf49 other 3.875174209124e-06 1 9.77501136642965e-06 6.38129381888046 -1.0221235240906 0.00801250813615984 28.5639655392594 10.3941675703431 2.74807629816926 0.00640471697126104 -50.1671463795592 47.2421348618852 -1.06191531196093 0.289237293461576 ANKRD36 other 1 1 1 2.74807629816926 -1.06191531196093 9.32141095626298e-06 79.1273833510334 24.893034537811 3.17869576048849 0.00165224725836595 -133.267659874344 57.7808394388078 -2.30643343310164 0.0218467014943759 EPC2 other 0.0765847124166567 1 1 3.17869576048849 -2.30643343310164 0.0174705342042352 152.987023535383 146.912063995576 1.0413509917061 0.298640796646463 -830.879967334446 392.336196951806 -2.11777545327155 0.0351046746618066 ARHGEF4 other 1 1 1 1.0413509917061 -2.11777545327155 6.22707612201333e-07 240.327460497991 59.3269728294007 4.05089707154065 6.66763653644949e-05 -296.88618546651 127.635174328939 -2.32605304162769 0.0207536515974609 ISCU essential 0.00563986284370747 1 0.636892641961655 4.05089707154065 -2.32605304162769 1.58633712231382e-05 218.959681535887 46.7427789329008 4.6843531029724 4.44093240256789e-06 48.3812352891131 100.812854368182 0.479911372337682 0.631676099484778 ALDH1L2 other 0.127731865088709 1 0.0469095689683247 4.6843531029724 0.479911372337682 0.455513881965003 8.89951791896296 8.23348601241999 1.08089306346525 0.280698598942594 16.7337949232301 17.8443825823913 0.93776261778555 0.349195292729534 STAB2 other 1 1 1 1.08089306346525 0.93776261778555 0.415570016945243 4.77895593208011 6.51523967952386 0.733504240388798 0.463882674041115 -12.699760026179 15.0149727289228 -0.84580639974896 0.398404198304234 USP44 other 1 1 1 0.733504240388798 -0.84580639974896 2.37702978917148e-08 217.800615473415 58.1324603221264 3.74662648486796 0.000218998433372004 -422.46033210991 119.95770126076 -3.52174414539321 0.000502875833440737 SCYL2 other 0.000236704626405696 1 1 3.74662648486796 -3.52174414539321 9.41749010083144e-05 719.600499825387 306.572857643038 2.34724138776585 0.0196328750256003 -1865.32411530179 663.882379345653 -2.80972077785876 0.00531970272212824 CKAP4 other 0.700472913699843 1 1 2.34724138776585 -2.80972077785876 0.0768512254611193 -59.5455305701954 40.2956525728612 -1.47771600081491 0.140645033902843 -190.874039621506 92.3442790024548 -2.06698283514057 0.0396853619164234 PLXNC1 other 1 1 1 -1.47771600081491 -2.06698283514057 0.000383323292934243 125.21703662476 64.4688360277219 1.94228784541598 0.0531381919096173 -386.367509894652 139.607023872815 -2.767536325727 0.00603732664128911 APPL2 other 1 1 1 1.94228784541598 -2.767536325727 3.02391027518826e-13 272.683355607418 39.4469473865856 6.91266051426193 3.40376268823603e-11 -156.82616739473 87.7076053608013 -1.78805665426158 0.0748840122795746 PWP1 essential 3.79319304919616e-09 1 4.61141769002217e-07 6.91266051426193 -1.78805665426158 0.741423086061189 -71.6384878009193 159.52743104933 -0.449066892945621 0.653742304058534 -256.964876386401 351.005168416258 -0.732082885120557 0.464750613835634 DRAM1 other 1 1 1 -0.449066892945621 -0.732082885120557 2.84092772719381e-05 123.628426632258 36.2161078282956 3.41363095168574 0.000738688011725943 -152.305069525187 78.1093740600536 -1.94989489236067 0.0522159731856767 WASHC4 other 0.223154872971074 1 1 3.41363095168574 -1.94989489236067 0.280024274175184 -11.3437373327928 17.149172205572 -0.661474338050388 0.508866058704447 -58.8012142894909 36.9854939071872 -1.58984531711402 0.113027023671981 SLC41A2 other 1 1 1 -0.661474338050388 -1.58984531711402 1.08026653547392e-05 55.6847417667424 23.5646045506317 2.36306710121515 0.0188281739418252 -236.3199710209 73.5575144607327 -3.21272371359223 0.00147304884176803 VILL other 0.0882469732828647 1 1 2.36306710121515 -3.21272371359223 0.00434870483209197 1148.19122966652 518.973916134237 2.21242569996434 0.0277650142147074 -2047.5978407708 1236.43614934887 -1.65604818481658 0.0988609852669413 FLNB other 1 1 1 2.21242569996434 -1.65604818481658 1.87087982347947e-13 49.3753470205945 10.3546061134466 4.76844280503102 3.03489140157566e-06 -58.71036862877 16.9214392502137 -3.46958481253469 0.000606252462685287 NEK3 other 2.36535336082509e-09 1 0.0324854775624659 4.76844280503102 -3.46958481253469 0.345163491970628 4.95761845244854 12.727295118587 0.389526478820187 0.697193790380309 -21.6357086461621 20.6669401740731 -1.04687527345264 0.296093365423705 PCDH8 other 1 1 1 0.389526478820187 -1.04687527345264 1.81900146592132e-26 212.308039314115 40.9222092293122 5.18808840755452 4.16777670337096e-07 -484.486659254196 66.7904363838903 -7.25383281626609 4.26145649134013e-12 VPS36 other 2.80671926191659e-22 6.80043226888058e-08 0.00474167955542514 5.18808840755452 -7.25383281626609 4.49628447326523e-15 142.541187440134 28.1799632560943 5.05824603619054 7.79274481107722e-07 -170.907026709351 46.2014987545188 -3.69916628933245 0.000261704751527872 RNASEH2B other 5.9620732115497e-11 1 0.00870527522845437 5.05824603619054 -3.69916628933245 3.40217919866775e-14 374.805194333208 62.797238746535 5.96849800746835 7.4736828244128e-09 -236.501813178452 102.493366281411 -2.30748410125492 0.021781588708324 CKAP2 other 4.400038357637e-10 1 9.32715616486718e-05 5.96849800746835 -2.30748410125492 0.193201050164439 -4.68060447676429 63.4103531185423 -0.073814515241922 0.941212632309204 -167.655344526701 102.967516829551 -1.62823528904006 0.104641265294195 CNMD other 1 1 1 -0.073814515241922 -1.62823528904006 2.63574768389261e-06 210.117571466864 55.5486234701244 3.78258826845406 0.000194088159501266 -176.582225130478 112.493155161939 -1.5697152851325 0.117741108134433 TBC1D4 other 0.0226358011092697 1 1 3.78258826845406 -1.5697152851325 0.000203283003182688 76.2314871811181 25.2523415748124 3.01878884994785 0.00277966006012222 -46.3489087993387 41.2151480885511 -1.12456004524739 0.261770581661875 THSD1 other 1 1 1 3.01878884994785 -1.12456004524739 2.96253705204933e-15 96.0873319705569 13.783702877117 6.97108264935658 2.74555180227215e-11 -46.9257850443644 28.3252827763863 -1.65667490117644 0.0988297269947983 BORA essential 3.94224805516205e-11 1 3.73010667856695e-07 6.97108264935658 -1.65667490117644 5.79730349232246e-05 87.2838829626057 28.1153853119829 3.10448823638938 0.00210649829965923 -56.3883148782529 44.2309094513675 -1.27486220784704 0.203441965841953 LRCH1 other 0.441406687905432 1 1 3.10448823638938 -1.27486220784704 4.08633966877692e-18 227.616645071155 32.0061843342592 7.11164575864531 1.00660863033386e-11 -109.27956091705 51.1263544224782 -2.13744089817215 0.0334505975190224 SUCLA2 other 5.80096779379571e-14 1 1.38499281447636e-07 7.11164575864531 -2.13744089817215 1.62191407582747e-06 78.1212804166074 36.3907625819828 2.1467338102798 0.0326955527091127 -184.686875274225 58.539138670799 -3.15492983784458 0.00178487129263508 RCBTB1 other 0.0142112111324003 1 1 2.1467338102798 -3.15492983784458 8.3497781009662e-24 212.292203230531 35.2955561863576 6.01470060734122 5.76959993240583e-09 -310.562935914434 56.7773608316506 -5.46983747334219 1.01830223186021e-07 MED4 essential 1.26891577800383e-19 0.00160901935656231 7.23623223522339e-05 6.01470060734122 -5.46983747334219 1.09711917935104e-07 18.6940950602159 29.2098375702762 0.639993119278379 0.522713808673768 -222.307728317864 46.9877136601831 -4.73118845333914 3.58541038088825e-06 PHF11 other 0.00104840708778785 0.0556383982906238 1 0.639993119278379 -4.73118845333914 2.07104151890217e-26 162.442194229988 26.6095835824524 6.10464999298635 3.53936120920203e-09 -257.237684843561 41.9970833745673 -6.12513213237421 3.16151186708537e-09 COG3 essential 3.19520285536227e-22 5.02996538053282e-05 4.48047735472885e-05 6.10464999298635 -6.12513213237421 0.724370285318342 156.739833808989 330.40108529138 0.474392611848596 0.635632405797843 -252.742933728579 669.104979232226 -0.377732854444742 0.705948278335945 LMO7 other 1 1 1 0.474392611848596 -0.377732854444742 0.124157431249079 145.109388995522 98.775224120136 1.46908691210897 0.14307146469183 -130.160334692897 200.109140501862 -0.650446723055542 0.516003408809902 SCEL other 1 1 1 1.46908691210897 -0.650446723055542 8.5189173712099e-09 2837.79767404136 1014.77440206421 2.79648133444127 0.00553473353955031 -5514.923227593 1602.07684697525 -3.44235873454214 0.00066745826522928 ITM2B other 8.71655625422197e-05 1 1 2.79648133444127 -3.44235873454214 0.00335537371775166 14.6634937998776 68.6004810325805 0.213752055075437 0.830917469974426 -342.134819306887 116.900606962223 -2.92671550813633 0.00374630567758302 SPRY2 other 1 1 1 0.213752055075437 -2.92671550813633 8.5964568196535e-18 246.583253812789 35.3140227254123 6.98258750440646 2.20540738828377e-11 -126.509803204637 56.8070665925028 -2.2270082014996 0.0267624093883076 NUDT15 other 1.21390566750327e-13 1 3.00420594432015e-07 6.98258750440646 -2.2270082014996 0.577267215874781 -3.75617144263655 102.874968521495 -0.0365120057543613 0.970903242988807 193.504444867916 208.247190964669 0.929205546406368 0.353678889064389 EDNRB other 1 1 1 -0.0365120057543613 0.929205546406368 0.000640902455550224 5.22881476828349 20.0550854568253 0.260722637135609 0.794502963962194 -104.781289935097 32.261138412996 -3.24791049198955 0.00130790434285859 RCBTB2 other 1 1 1 0.260722637135609 -3.24791049198955 0.973539688342526 48.1446786000443 512.671001439135 0.0939095023219488 0.925250438501204 186.675846836827 811.002551863722 0.230179111530336 0.818126246220358 LCP1 other 1 1 1 0.0939095023219488 0.230179111530336 1.94348429327496e-08 39.2104832851014 13.4953687709357 2.90547697885419 0.00396727706911539 -71.5820040615416 21.7090054685062 -3.29734147266154 0.00110542385757615 SETDB2 other 0.000194503908070958 1 1 2.90547697885419 -3.29734147266154 7.6315390752686e-11 565.248679938899 92.4243881725253 6.11579574520709 3.32857777431373e-09 -387.713961941963 253.319237458606 -1.53053501120427 0.127046508988515 SCRN1 other 8.72819124038469e-07 1 4.2173080400555e-05 6.11579574520709 -1.53053501120427 1.65487361623021e-20 80.5708036686679 9.68090776368916 8.32264965594139 4.27094938545692e-15 -96.1017349891536 28.3458956021527 -3.39032275917418 0.000802030083894702 C7orf25 other 2.43365714002814e-16 1 6.25608665981729e-11 8.32264965594139 -3.39032275917418 0.399484297810634 -169.199720350469 157.694517756955 -1.07295879880393 0.284240596886149 -499.509658884837 442.233906946476 -1.12951460989013 0.259675929087802 TNS3 other 1 1 1 -1.07295879880393 -1.12951460989013 4.80892108450533e-06 3.78274849439408 0.788227239688906 4.79905832217501 2.63711277047481e-06 -0.0810830454234898 2.27996469600165 -0.0355632898902708 0.97165676117544 SPDYE1 other 0.0404382173996053 1 0.028370059184768 4.79905832217501 -0.0355632898902708 1.01132371938456e-06 336.710571595446 67.4958130940358 4.98861419931838 1.09260509079348e-06 -109.126628676066 191.045276873159 -0.571208199763652 0.56833543262506 IGF2BP3 other 0.00899875845508378 1 0.0120798418838127 4.98861419931838 -0.571208199763652 2.03066017409166e-05 13971.3805584934 3177.80136839134 4.39655564928087 1.58510508348123e-05 -4329.52510694725 8994.69040289069 -0.481342315634992 0.630664541567471 GPNMB other 0.161924842282069 1 0.160143166584109 4.39655564928087 -0.481342315634992 5.92249482036197e-06 195.844456780616 48.7821107835372 4.01467779140687 7.72549000303763e-05 -246.175039649204 139.007441206737 -1.77094864499436 0.0777016125698646 RAPGEF5 other 0.0493936068018188 1 0.733535275788423 4.01467779140687 -1.77094864499436 1.5701904734301e-07 713.456622203547 227.571316849403 3.13509027447287 0.00190624471509909 -2438.70660549409 602.84981088359 -4.0452971228766 6.81327075699891e-05 RAC1 essential 0.00148414403548613 1 1 3.13509027447287 -4.0452971228766 3.33026336191037e-09 1128.62560718482 220.375931254251 5.1213651180569 5.73820049657985e-07 -1621.19445296818 583.952713235893 -2.77624269263954 0.00587955553530351 KDELR2 other 3.48811784526493e-05 1 0.0064640828593972 5.1213651180569 -2.77624269263954 6.44547776883027e-13 116.906004830384 20.4421781890623 5.71886242988212 2.84833080394396e-08 -210.427548974728 57.8610940885894 -3.63677099939639 0.000330809723715709 NUPL2 other 8.00463884111031e-09 1 0.000345815842906836 5.71886242988212 -3.63677099939639 0.0877989042270287 26.6463356333551 139.304051611472 0.191281842309034 0.848449620487597 854.718754481856 393.103939659086 2.17428183300096 0.0305590021440919 IL6 other 1 1 1 0.191281842309034 2.17428183300096 3.19511991432604e-11 229.630985051112 36.5711212274534 6.27902501602088 1.3359851805569e-09 -216.558950113963 96.9062517186221 -2.23472630788327 0.0262445937726856 ZDHHC4 other 3.71496592438688e-07 1 1.71941292737673e-05 6.27902501602088 -2.23472630788327 0.0988755976589476 160.900956119522 77.523643146715 2.07550818806352 0.0388757086532221 27.6385283510683 201.722943017587 0.137012319657951 0.891122046586862 AOAH other 1 1 1 2.07550818806352 0.137012319657951 5.78074079009085e-09 583.376131224149 108.432157938611 5.38010256656913 1.60668896521196e-07 -592.920668178286 291.714784657306 -2.03253554280707 0.0430707936876614 BZW2 other 5.97381753247988e-05 1 0.00187725538695365 5.38010256656913 -2.03253554280707 0.214778729115421 2.56827586482496 3.54351772024279 0.724781436862404 0.469209136002033 -12.8217364634139 9.23944460490907 -1.38771722886909 0.16635892743959 DGKB other 1 1 1 0.724781436862404 -1.38771722886909 3.84222206188757e-32 730.173760749193 57.6792243021735 12.6592160276621 3.44901301166607e-29 -303.156316093545 171.004602091279 -1.772796242827 0.0773816387872573 TBRG4 other 6.04496796996771e-28 1 5.43323019727755e-25 12.6592160276621 -1.772796242827 2.57644576888367e-31 536.861673079308 46.3727730693493 11.5770879666059 1.95309750758371e-25 -439.531433133523 134.377886763122 -3.27086132786354 0.00121153978940062 DDX56 essential 4.0463080800318e-27 1 3.05405857260865e-21 11.5770879666059 -3.27086132786354 1.7722956798288e-22 124.093274122748 12.8306312388877 9.67164216727234 3.22890067587718e-19 -66.8519989389565 35.8209060577343 -1.86628442148303 0.0630737156648637 HUS1 essential 2.66393763635067e-18 1 4.9211675201044e-15 9.67164216727234 -1.86628442148303 0.180872186594204 26.6686126491554 15.2023521346201 1.75424252859025 0.0805150660215107 -3.94707213804228 45.0712056045152 -0.0875741415190114 0.930279592691879 NACAD other 1 1 1 1.75424252859025 -0.0875741415190114 4.636252040982e-06 157.912021727668 41.6731935508668 3.78929494652045 0.000186047274908321 -268.293614921713 123.550688610254 -2.17152666601525 0.0307557347373293 CCM2 other 0.0390882409575192 1 1 3.78929494652045 -2.17152666601525 0.106232976408139 -71.291626869403 33.6038744048254 -2.12152997629243 0.0347815146125857 -44.6429336085488 96.9159753729352 -0.460635446702792 0.645428239261153 MYO1G other 1 1 1 -2.12152997629243 -0.460635446702792 2.65233229967925e-05 805.557986242462 193.578968036697 4.16139208929842 4.24721160444985e-05 -611.360196348506 528.168507266363 -1.15750974913805 0.248079592084652 TTYH3 other 0.208977261891728 1 0.413211216996926 4.16139208929842 -1.15750974913805 1.19366957935565e-07 134.190643351904 39.2181043345561 3.42165042469087 0.000718120693579889 -165.878617050645 76.8570812304802 -2.15827369963746 0.0317816234833115 CIDEB other 0.00113792520999974 1 1 3.42165042469087 -2.15827369963746 5.79258184528967e-16 138.667280874615 22.4498753188482 6.17675060129149 2.37582282461018e-09 -139.929936282849 50.832447155306 -2.75276804705718 0.00630709171981646 TTC5 other 7.84836914218297e-12 1 3.02608553170598e-05 6.17675060129149 -2.75276804705718 0.0310317980372654 9.05461985668352 4.75773776046848 1.90313554730094 0.0581358804780067 -4.58621955079062 8.73711160141778 -0.524912552341257 0.600094737900097 NKX2-8 other 1 1 1 1.90313554730094 -0.524912552341257 0.111582594205846 -127.892137461327 85.7051069026236 -1.49223473470064 0.136859380012605 -323.255079024377 157.388893949029 -2.05386206684358 0.0409968479944892 NKX2-1 other 1 1 1 -1.49223473470064 -2.05386206684358 0.108731077182551 -3.88642646906843 7.06946582785721 -0.549748250250249 0.582941507231141 -29.0417267812653 14.3225202410247 -2.0276966827444 0.0435624241681071 ZFHX2 other 1 1 1 -0.549748250250249 -2.0276966827444 3.63180179620645e-07 106.344285456018 22.5746560472948 4.71078209268052 3.93383986545458e-06 -51.8924718943138 43.7452946405976 -1.18624122481405 0.236558400054927 MTHFS other 0.00335459370636966 1 0.0417525010721603 4.71078209268052 -1.18624122481405 0.933961864293587 -0.2372662323314 22.7287939462433 -0.0104390155013314 0.991678646288648 -15.4112034389709 44.0439839225365 -0.349904846620501 0.726679897111922 ADAMTS7 other 1 1 1 -0.0104390155013314 -0.349904846620501 0.00908738230254931 124.573645878051 85.059821148183 1.46454159198184 0.144200851244531 -340.492809760897 166.756767781017 -2.04185301917119 0.0421307111061936 ABHD17C other 1 1 1 1.46454159198184 -2.04185301917119 6.43035549973862e-14 423.414393322995 58.2460757004892 7.26940636310437 3.83997421881679e-12 -126.477332234828 112.086740779397 -1.1283879909021 0.260150376785606 IREB2 other 8.24500182176486e-10 1 5.33910015384286e-08 7.26940636310437 -1.1283879909021 0.352563438792188 58.9556643772876 48.9425531180644 1.20458906659545 0.229432657674998 -38.7491525947798 98.0472433762466 -0.395208995790772 0.693005396170695 ALPK3 other 1 1 1 1.20458906659545 -0.395208995790772 0.757049906839166 -6.86681108570278 10.337700667684 -0.664249363223361 0.507097582412789 -11.0941376914323 20.1335139584449 -0.551028385523277 0.582069886253029 TM6SF1 other 1 1 1 -0.664249363223361 -0.551028385523277 6.36316626719321e-06 124.285076011853 27.8816375173674 4.4575960050566 1.21288684070228e-05 -28.4615997303376 53.9232932259762 -0.527816422692577 0.598057062192576 CIB2 other 0.0529160906779787 1 0.123714457751633 4.4575960050566 -0.527816422692577 1.79203233005056e-08 344.103981992467 74.8735084429176 4.59580416556553 6.62491894231569e-06 -393.184239900253 165.016797088508 -2.38269222792735 0.0178788361497465 CALCOCO2 other 0.000179794603673973 1 0.0690449052168141 4.59580416556553 -2.38269222792735 2.24488662477001e-12 171.019716836784 25.2935246096609 6.7614031447188 8.32182897145741e-11 -70.9631519823361 55.8589134875652 -1.27039979032412 0.205027834793455 RSAD1 other 2.73045560170776e-08 1 1.11512508217529e-06 6.7614031447188 -1.27039979032412 1.12411974253764e-14 469.330411626675 70.6192067617624 6.64593151279631 1.63082930404019e-10 -358.570833565253 148.368625744192 -2.41675645215908 0.0163154625497832 NMT1 essential 1.47282168667281e-10 1 2.16704597920861e-06 6.64593151279631 -2.41675645215908 0.000339783330675027 13.8948693614301 3.8338734002851 3.62423792094878 0.000345816867059253 -4.53262381127619 8.46683117097114 -0.535338867605683 0.592852967156315 MYCBPAP other 1 1 1 3.62423792094878 -0.535338867605683 1.44206845223019e-05 487.666626639126 112.113750351417 4.34974858222609 1.92927411127993e-05 -189.051624440691 240.537737788063 -0.785954113392649 0.43257850872322 SRSF1 essential 0.116576813678289 1 0.19352548610249 4.34974858222609 -0.785954113392649 2.58480786750412e-06 223.906551707574 46.7677146061993 4.78763081739073 2.77448638507243e-06 -60.8647269321295 100.339166584224 -0.606589919012732 0.544629036032517 VEZF1 other 0.0222345172762704 1 0.029800758262063 4.78763081739073 -0.606589919012732 0.545880886777141 0.239994463087161 2.89238670747134 0.0829745422585541 0.93393258811383 -6.51289103856329 6.44958168246066 -1.00981604067048 0.313477604927934 CHAD other 1 1 1 0.0829745422585541 -1.00981604067048 2.13779021612067e-19 163.105131855729 17.0394473583046 9.57220785545227 6.77796217743851e-19 -28.7468357190502 37.7482325052182 -0.761541238124894 0.446993622927422 TACO1 other 3.09894069728852e-15 1 1.03086026756662e-14 9.57220785545227 -0.761541238124894 8.94866117847842e-09 335.889620165211 55.3689701582562 6.06638735026437 4.367213030454e-09 -32.9531833037399 122.339641466391 -0.269358181115748 0.787858281798754 TEX2 other 9.14821632275849e-05 1 5.50487202488726e-05 6.06638735026437 -0.269358181115748 1.27253900136482e-13 773.638852850361 102.850115973531 7.52200272724498 7.95805135407871e-13 -298.846894055372 228.56193832166 -1.30750944907895 0.192147919779241 DCAF7 other 1.61688805513414e-09 1 1.12335852914175e-08 7.52200272724498 -1.30750944907895 0.341072662601998 59.0463996203376 41.9350647556879 1.40804360180054 0.160260054247168 -7.49912908521901 92.900581881113 -0.0807220895001046 0.935722331175048 LIMD2 other 1 1 1 1.40804360180054 -0.0807220895001046 2.65131572830222e-12 132.514270779084 17.9135453991177 7.39743405488066 1.80282031846956e-12 1.39189566326552 38.7914534876576 0.0358815032210221 0.971403655731458 BRIP1 other 3.21498545213927e-08 1 2.52521042008031e-08 7.39743405488066 0.0358815032210221 2.37245003127744e-16 248.659941305942 35.0967820486102 7.08497835959833 1.21008625722767e-11 -247.507342579977 78.1022010790351 -3.16901878769733 0.00170550703511381 KAT7 other 3.24503715278128e-12 1 1.66108540529642e-07 7.08497835959833 -3.16901878769733 0.23145533339625 13.854468614901 8.70673685455788 1.59123548194158 0.112744282752304 -37.5615129557585 76.5779471299263 -0.490500390302049 0.62418421672686 RTP4 other 1 1 1 1.59123548194158 -0.490500390302049 2.5717849771501e-29 649.660275549928 49.7273332111309 13.0644503454794 2.24652380586775e-30 392.037895592098 537.466145646183 0.729418771336305 0.466397123276464 ACTL6A essential 4.01841402679703e-25 1 3.54546387042048e-26 13.0644503454794 0.729418771336305 1.7341273964601e-17 470.149980435356 49.9222303782326 9.41764774677124 2.50225243208838e-18 603.001816687185 539.572645682184 1.1175544600205 0.264781048784117 NDUFB5 other 2.43350097545246e-13 1 3.78991153364106e-14 9.41764774677124 1.1175544600205 5.85684629144914e-25 225.820147968517 19.4054395068829 11.6369509635904 1.65571435184596e-25 425.5755384223 209.73911333737 2.02907093317283 0.0434621154955501 MRPL47 other 8.96624598757948e-21 1 2.58986838915746e-21 11.6369509635904 2.02907093317283 4.17251371703344e-25 501.543063559613 43.632327516682 11.4947584074642 4.12755240684772e-25 -566.148515876581 420.492821379866 -1.3463928207353 0.179317748231582 TRA2B essential 6.39437727135375e-21 1 6.45301543286572e-21 11.4947584074642 -1.3463928207353 0.0199350647535691 53.3155229011142 19.042343938436 2.79984034914418 0.00548046532987259 62.8163459817216 45.8999970256734 1.36854793142114 0.172274057866156 SCN2A other 1 1 1 2.79984034914418 1.36854793142114 9.23265611916592e-10 515.672623250945 90.3603173515815 5.70684829762741 3.0035089861753e-08 -289.545985353733 236.474200566427 -1.22442949235131 0.22184966922603 MARCH7 other 9.99250371777327e-06 1 0.000364265569843341 5.70684829762741 -1.22442949235131 0.0262872410687239 14.9764330411589 5.51462662220504 2.7157655571558 0.00703572441455737 13.9107006485586 14.7032702285516 0.946095693837288 0.344939482684528 ERMN other 1 1 1 2.7157655571558 0.946095693837288 0.0593950175177258 -116.347453972641 56.3846465746796 -2.06345984307169 0.0400176759829254 -278.452191708161 151.460890829336 -1.83844284939481 0.0670874347338564 GALNT5 other 1 1 1 -2.06345984307169 -1.83844284939481 0.949287763684581 -12.7133079010899 57.9563790597585 -0.219359941171984 0.826534800630928 18.8657283991234 139.699064099574 0.135045488820715 0.89267615688089 SCN7A other 1 1 1 -0.219359941171984 0.135045488820715 0.0186470020713204 32.6817110748598 36.7933930298356 0.888249448708312 0.375194282097175 -190.832676273337 88.9913454122957 -2.14439590040146 0.0328906485629937 TANK other 1 1 1 0.888249448708312 -2.14439590040146 0.556587162722845 -13.4534654554549 16.5488477392475 -0.812954815189245 0.416957582769025 -29.6550444033696 27.8932006450568 -1.06316391513231 0.288654065289902 BLK other 1 1 1 -0.812954815189245 -1.06316391513231 0.00201088472630306 46.8611934164493 13.1588248940275 3.56119895156585 0.000435919321562418 50.8032728869092 22.179293012153 2.29057224047096 0.0227562839087153 GATA4 other 1 1 1 3.56119895156585 2.29057224047096 1.31776064832609e-06 224.350487522639 42.7757676986143 5.24480329852516 3.23654059129788e-07 -355.423093811031 416.848800132298 -0.852642717690989 0.394639208266088 SKIL other 0.0116279199608294 1 0.00371069378792302 5.24480329852516 -0.852642717690989 1.99301340980596e-09 892.94680965271 135.987195825795 6.56640358108868 2.6188816249818e-10 205.673481124769 382.254514988325 0.538053765384696 0.590981537833297 EPRS essential 2.11917115864668e-05 1 3.45247164621351e-06 6.56640358108868 0.538053765384696 0.126004376010328 -3.33391372629353 9.73010608262103 -0.342638990570539 0.732133729574786 52.7755258351233 26.8077726826336 1.96866507560742 0.0500030674136529 HLX other 1 1 1 -0.342638990570539 1.96866507560742 6.8101994915618e-07 158.473221114275 30.0407945706 5.27526729500583 2.77167903165184e-07 -134.856523213987 101.969620571724 -1.3225166717094 0.187145050353007 VPS45 other 0.00614688606108368 1 0.00319075690123759 5.27526729500583 -1.3225166717094 0.965694995269501 -0.531225775684045 2.41304645771467 -0.22014734692972 0.825920934973241 -1.1516348691128 6.86988902569687 -0.167635148807368 0.866994429380809 IL10 other 1 1 1 -0.22014734692972 -0.167635148807368 4.64987890279274e-05 231.019341383156 51.1430655978539 4.51711954851707 9.36540311195412e-06 1.27747237894358 140.518430814801 0.00909113752221758 0.992753110408176 KCTD3 other 0.357064200945454 1 0.0963980942313437 4.51711954851707 0.00909113752221758 2.09961356623471e-05 160.930168693606 34.5256539054808 4.66117655973082 4.93775850816411e-06 142.351788031505 94.0263161027532 1.51395687858218 0.131202161286613 RPS6KC1 other 0.167129239872283 1 0.0519699082984273 4.66117655973082 1.51395687858218 0.000180330695767037 91.5936377847944 22.9207802126954 3.99609598516469 8.31264427218024e-05 -14.7940386639425 69.6075403706254 -0.212535001023906 0.831850042196523 CBWD2 other 1 1 0.786293021705529 3.99609598516469 -0.212535001023906 0.508491216129947 94.2523813699148 93.5119504711192 1.00791803502189 0.314396227101509 -83.695104939699 291.27013099291 -0.28734530607169 0.774068345246622 IL36G other 1 1 1 1.00791803502189 -0.28734530607169 0.104336983375108 -420.110336141823 263.844851305683 -1.5922627789128 0.11249570680143 -1480.50538050106 821.821425116633 -1.80149280032575 0.0727407856382289 IL1RN other 1 1 1 -1.5922627789128 -1.80149280032575 0.822814953002325 -0.664398220847564 8.88754132451814 -0.0747561329492424 0.940464101246806 -17.0871780666863 27.6828289085554 -0.617248263287336 0.537591169248802 IL36A other 1 1 1 -0.0747561329492424 -0.617248263287336 0.0115778728963725 186.164802754816 62.960302792229 2.95686002923407 0.00338279291689948 50.2843694451305 196.108150340737 0.256411420727602 0.79782843261444 IL36RN other 1 1 1 2.95686002923407 0.256411420727602 1.41909667521019e-11 647.181494817352 112.052598324589 5.77569377679779 2.082928793468e-08 -709.937224896252 303.808300422891 -2.33679337894337 0.0201733401288586 SMPD4 other 1.67495980575059e-07 1 0.000254533898561789 5.77569377679779 -2.33679337894337 1.65726002436236e-09 299.46519641512 58.3554062494669 5.13174726493923 5.48128155007712e-07 -352.601761507926 157.912904446163 -2.23288757017409 0.0263731693147857 WDR33 essential 1.76879362400195e-05 1 0.00618178933217697 5.13174726493923 -2.23288757017409 2.01050409257818e-09 142.573452793566 38.9759053494955 3.65798950698169 0.000304991389702349 -406.187672390947 105.675403682944 -3.84372955517279 0.000150805062809978 CCDC115 essential 2.1371658504106e-05 1 1 3.65798950698169 -3.84372955517279 3.18070864326565e-09 195.672777549156 35.8756804094015 5.45419000604873 1.11179163036021e-07 -147.11970169927 97.0500234391751 -1.51591618925755 0.130710397011868 SAP130 essential 3.33719950851432e-05 1 0.00131180294466201 5.45419000604873 -1.51591618925755 0.039113978401108 114.544021149229 50.9485586959114 2.24822888185886 0.0253655290010361 -58.0315700753212 138.626692581386 -0.41861757641842 0.675827207803513 BIN1 other 1 1 1 2.24822888185886 -0.41861757641842 4.95292802707616e-12 381.955830904006 65.2896429645278 5.85017490617193 1.4018159137116e-08 -438.46702752481 177.019861751103 -2.4769368995515 0.0138574663648597 IMP4 essential 5.93558894764807e-08 1 0.000172857920319778 5.85017490617193 -2.4769368995515 0.0579426295041796 91.4169832438084 160.360145914438 0.570072961224323 0.569098776332944 -857.504414696669 429.900960407709 -1.99465573159788 0.047078290837042 HS6ST1 other 1 1 1 0.570072961224323 -1.99465573159788 3.08205162856448e-06 509.349685338901 109.249434345935 4.66226382212709 4.92149192925816e-06 -160.457729020083 295.538928962337 -0.542932633556819 0.587624092519257 UGGT1 other 0.0263361311660835 1 0.0518134670312299 4.66226382212709 -0.542932633556819 0.728132505569239 -18.5743553267769 49.2705166935417 -0.376987224272637 0.706478126731287 72.2566120119724 134.060883091277 0.538983559900732 0.590340690469675 GYPC other 1 1 1 -0.376987224272637 0.538983559900732 5.01802194179496e-19 147.109008695914 27.4543813937247 5.3583071709472 1.79214701517151e-07 -182.256572933115 46.6274287180263 -3.90878454901062 0.000117167655787526 STAM other 7.23498403567997e-15 1 0.00208713441386873 5.3583071709472 -3.90878454901062 3.63732753789286e-09 375.463167415999 107.496959799103 3.49277940620541 0.000558041991551104 -488.197655342431 177.944106880259 -2.74354494735219 0.00648353310224277 ABI1 other 3.80173474260561e-05 1 1 3.49277940620541 -2.74354494735219 9.77526765420882e-27 666.255324400461 112.12434419227 5.94211122660367 8.61963577752578e-09 -1099.46062677911 185.604005212012 -5.92369020012913 9.51969426126346e-09 YME1L1 other 1.51076761595797e-22 0.000151267941811476 0.000107340324337529 5.94211122660367 -5.92369020012913 5.5241453499111e-08 59.4401939906425 30.1569616043872 1.97102727955177 0.0497419526190968 -178.966585966767 50.8326924135119 -3.52069854004419 0.000505064511831096 DNAJC1 other 0.000537554583999849 1 1 1.97102727955177 -3.52069854004419 1.14817198431604e-09 263.316969985366 49.5791994303706 5.31103714885857 2.26295502563196e-07 -114.046040528541 100.783959975843 -1.13158919887527 0.258800196864236 NIPSNAP3A other 1.23577750671935e-05 1 0.00261891785116387 5.31103714885857 -1.13158919887527 2.54000565202338e-11 1056.69490546922 261.260808793086 4.0445978497529 6.83891189442506e-05 -1884.67350452828 486.896575242056 -3.87078817219311 0.00013600335760563 LRRC8A other 2.96393259534609e-07 1 0.65243219472815 4.0445978497529 -3.87078817219311 1.48908781686151e-21 3344.87900235245 511.243201586479 6.54263761742492 2.98867556129082e-10 -4561.16980577799 989.99231963592 -4.60727797106083 6.27594664906413e-06 TXN essential 2.21740066808848e-17 0.0969131681548483 3.93190156843421e-06 6.54263761742492 -4.60727797106083 1.08965888871856e-09 327.568226426358 54.1789847602566 6.0460384755428 4.88182080558292e-09 -5.37421918728411 100.861539038122 -0.0532831368481585 0.957545428387873 ODF2 other 1.17421641848312e-05 1 6.14279511966499e-05 6.0460384755428 -0.0532831368481585 2.25989144254514e-21 421.609213416376 82.4532291598038 5.11331354408508 5.97910012158961e-07 -953.783512097925 159.761205630038 -5.97005705068739 7.38227720576046e-09 KIAA0368 other 3.35978060763187e-17 0.000117348678462768 0.00673007509686127 5.11331354408508 -5.97005705068739 6.13163520155929e-17 120.489188297759 22.1290000253633 5.44485463236744 1.15914598412672e-07 -195.135788458988 42.3325297203101 -4.60959431785072 6.21145528389312e-06 TOR1B other 8.5064175151232e-13 0.0959235039491614 0.00136605354229334 5.44485463236744 -4.60959431785072 3.3421782845048e-26 345.202025274154 43.6662416664492 7.9054668343346 6.69902955579598e-14 -428.374088871754 83.5330322653771 -5.12819991390767 5.56378822913342e-07 C9orf78 essential 5.1529704790495e-22 0.00873737303503112 9.63320450123462e-10 7.9054668343346 -5.12819991390767 6.34185050547895e-20 428.990875109679 54.880444817373 7.81682576621312 1.19248773872131e-13 -252.563183023956 111.442415487669 -2.26631109814649 0.0242181065398154 SMC2 essential 9.26163847820146e-16 1 1.70919267590926e-09 7.81682576621312 -2.26631109814649 2.40772126413999e-06 272.377540760116 143.927783943055 1.89245976904558 0.0594993924336351 -971.91372365166 278.183562934451 -3.49378559034659 0.000556344352970501 KLF4 other 0.0207545572968867 1 1 1.89245976904558 -3.49378559034659 6.13939870123169e-27 206.485239047968 29.357238685378 7.03353749516 1.63111695878593e-11 -356.582498969464 56.1600694893848 -6.34939561527545 9.0258785410404e-10 TOR1A other 9.50071949015603e-23 1.43764193401692e-05 2.23120488792327e-07 7.03353749516 -6.34939561527545 4.37269073865974e-05 38.4733103489273 20.1990631612869 1.90470766102977 0.0578767466845417 -112.774554677129 37.5506850934005 -3.00326224133121 0.00292058962305558 RALGPS1 other 0.336740913784187 1 1 1.90470766102977 -3.00326224133121 3.27373692211908e-09 1182.54082035821 456.280292411994 2.59169821713546 0.0100681235108258 -3671.58237287819 846.509696503983 -4.33731874311839 2.03659363635076e-05 FAM129B other 3.43120366807301e-05 0.310886018588943 1 2.59169821713546 -4.33731874311839 0.0121781192769443 40.9577502891897 25.3142173099199 1.61797419164682 0.106827163623009 -76.0980540318673 47.1258538476143 -1.61478355974063 0.107516947579602 ST6GALNAC4 other 1 1 1 1.61797419164682 -1.61478355974063 0.000554719685511874 153.843791294598 47.9839691073947 3.20614976535755 0.00150770043942499 -66.4124666404427 92.6106619224144 -0.717114695671655 0.473925534457511 TMOD1 other 1 1 1 3.20614976535755 -0.717114695671655 2.22640899284904e-05 331.792385559108 127.605004318036 2.60015183050476 0.00982753290094012 -601.266834915626 244.637084524601 -2.45779104212289 0.0146035043237278 DAB2IP other 0.176932722661713 1 1 2.60015183050476 -2.45779104212289 0.0155359965222613 177.333274036346 79.7397552278028 2.22390040613663 0.0269794703385783 -116.25688547255 147.936426621381 -0.785857061223265 0.432637796517515 STXBP1 other 1 1 1 2.22390040613663 -0.785857061223265 6.25236689149477e-06 83.925952418849 27.3439375570448 3.06927092134273 0.00236350096144294 -118.177235574447 50.7295815041198 -2.32955273965448 0.0205647513322582 SLC2A8 other 0.052025944904128 1 1 3.06927092134273 -2.32955273965448 0.0538433603039719 -195.252095345659 90.0922174304365 -2.16724708209586 0.031087052401896 19.2593473221177 167.484227317053 0.114992006295967 0.908536612850638 ANGPTL2 other 1 1 1 -2.16724708209586 0.114992006295967 7.89416687882235e-09 1262.96317385539 241.948425047753 5.21996856811992 3.55723772483645e-07 -472.200800326434 462.734334558405 -1.02045766881998 0.308418216065106 CDK5RAP2 other 8.09467871754444e-05 1 0.004067345614578 5.21996856811992 -1.02045766881998 4.76748630178764e-07 22.8828358809514 5.49227038629476 4.16637096710544 4.161011950364e-05 -14.2859109399034 10.3823456557462 -1.37598105607251 0.169959363104135 ZFP37 other 0.00436129646887533 1 0.405116123487439 4.16637096710544 -1.37598105607251 0.00168604712042792 40.6991355762091 35.8476704765287 1.13533557509286 0.257234172442036 -172.671859687908 67.7648549076064 -2.54810343685288 0.0113813054616847 SLC31A2 other 1 1 1 1.13533557509286 -2.54810343685288 1.06377723929407e-29 447.292094158874 54.082884552499 8.27049255711725 5.98742440500664e-15 -546.529478020435 102.235899180242 -5.34576877987745 1.90809685092026e-07 SLC31A1 other 1.66491775721916e-25 0.00300906873390125 8.7524169952387e-11 8.27049255711725 -5.34576877987745 0.0501008786113721 -40.4290822337853 44.5394083306453 -0.907714847347178 0.364835353911119 -203.7025403195 82.984464863736 -2.45470692200026 0.0147289022865051 TLR4 other 1 1 1 -0.907714847347178 -2.45470692200026 4.35374875819933e-15 110.387888068649 18.9831347626062 5.81505054086725 1.71444391903003e-08 -115.234524205082 36.4677639251327 -3.15990101399295 0.00175848457104106 ZNF189 other 5.77394160312395e-11 1 0.000210533713256887 5.81505054086725 -3.15990101399295 8.26740769080479e-22 86.9190308234932 11.3917492104072 7.6299986260307 4.08055029416778e-13 -77.2572972387851 22.018939422354 -3.50867477115415 0.000527702222518508 STX17 other 1.23490268677551e-17 1 5.80254251830658e-09 7.6299986260307 -3.50867477115415 8.03050482669931e-29 497.354879902334 60.6820108736728 8.19608435418732 9.84588579514918e-15 -589.976064890243 114.710596468148 -5.14316970755237 5.17440677436429e-07 PRPF4 essential 1.25211631257896e-24 0.00812640583913912 1.43484093692709e-10 8.19608435418732 -5.14316970755237 1.58305638003382e-13 195.87178439494 43.4925867780698 4.50356713419731 9.92485890099964e-06 -344.66425426322 80.9673577051427 -4.25682971548086 2.85726106647139e-05 FPGS other 2.00509921095084e-09 0.434589408210298 0.101948150631068 4.50356713419731 -4.25682971548086 3.36845506889826e-08 92.4744660723936 29.1593857576537 3.17134478898003 0.00169107306158405 -190.014443161291 55.7815790499822 -3.40640129586564 0.00075769997156855 USP20 other 0.000332197038894746 1 1 3.17134478898003 -3.40640129586564 0.998213483052346 -0.259372155848668 6.20120502981746 -0.0418260893812606 0.966668364707233 0.234437526184255 11.9128944669453 0.0196793085706206 0.984313785728233 BAAT other 1 1 1 -0.0418260893812606 0.0196793085706206 0.181377795478809 18.0924520610112 10.1837087279113 1.77660737796082 0.0767505281395237 5.55232483904968 18.9257630952974 0.293373895207918 0.769460087054491 KIF12 other 1 1 1 1.77660737796082 0.293373895207918 4.06985390648163e-16 527.773828402183 94.7898727798088 5.56782927252334 6.18557703033864e-08 -698.770446425817 175.723107907795 -3.97654272534533 8.96893662790384e-05 ATP6V1G1 essential 5.53662925437761e-12 1 0.000739300166666074 5.56782927252334 -3.97654272534533 3.50089151857022e-32 285.259469406532 29.2659131920397 9.7471576415433 2.02451397218966e-19 -256.412021192467 56.5676401238436 -4.53283928109965 8.76543141309946e-06 TEX10 essential 5.50865280447025e-28 0.134987643761732 3.08880096736977e-15 9.7471576415433 -4.53283928109965 0.000916659109495331 8.1857481251229 9.06366847514178 0.903138519195987 0.367254446956105 -50.0452560849632 16.8152852045102 -2.9761764654185 0.00318222885322929 GARNL3 other 1 1 1 0.903138519195987 -2.9761764654185 9.87398126024212e-29 200.849937157799 24.1759463431641 8.3078417823586 4.8360926941414e-15 -236.941857721404 46.4434728475868 -5.1017256719577 6.36502805009493e-07 MRPL50 essential 1.53876123959613e-24 0.009991184530234 7.08003970422301e-11 8.3078417823586 -5.1017256719577 3.86802926795186e-21 301.532128064479 41.4285269953635 7.27836951813964 3.63241040843577e-12 -305.927497294677 77.1248300669512 -3.96665376155907 9.32779045735706e-05 DPM2 other 5.73512699559222e-17 1 5.05413584229753e-08 7.27836951813964 -3.96665376155907 0.60457699580029 2.63780671681394 10.1690083529438 0.259396651596842 0.795524710692538 -15.1008808061749 19.5543675980598 -0.772251044706412 0.440633765146813 WDR38 other 1 1 1 0.259396651596842 -0.772251044706412 5.10237323729748e-14 151.309874664638 23.9291271099016 6.32325090546356 1.06141597483327e-09 -102.679081643469 46.1840139967091 -2.22326023136027 0.0270292747213433 TSTD2 other 6.56420316978321e-10 1 1.37039416510724e-05 6.32325090546356 -2.22326023136027 0.475460437302779 1.40522956705686 6.56396295735031 0.214082495009099 0.830644310235295 15.0427071715871 12.7600864219102 1.1788875619022 0.239480783391978 GABBR2 other 1 1 1 0.214082495009099 1.1788875619022 1.42909304042033e-24 763.016776991295 92.4953306519087 8.24924643885847 6.90293616491498e-15 -708.510069488619 178.389795920491 -3.97169617148059 9.14313949577321e-05 PSMB7 essential 2.18265380063397e-20 1 1.00817382688583e-10 8.24924643885847 -3.97169617148059 0.431461814480401 -34.7830848946881 27.0537124885152 -1.2857046850577 0.199639649935837 -36.845427585549 52.1767554719075 -0.706165556909473 0.48068959977886 NR5A1 other 1 1 1 -1.2857046850577 -0.706165556909473 1.87851910550461e-31 61.9848515199285 7.42733030919756 8.34550894325653 3.75565691113379e-15 -89.957036727371 14.4216635141817 -6.23763247831367 1.71572380662205e-09 TRMO other 2.9517170704794e-27 2.7314323001423e-05 5.50579303172214e-11 8.34550894325653 -6.23763247831367 7.97418067332605e-21 160.271000977962 22.3914777464466 7.15767859508049 7.59242021834603e-12 -173.829073020816 43.0661962193863 -4.03632287688706 7.05711719700061e-05 RABEPK other 1.17810545267719e-16 1 1.04737436912083e-07 7.15767859508049 -4.03632287688706 2.97712536350789e-13 98.381129071658 20.2648467855776 4.85476796901695 2.03117798013273e-06 -146.41853932742 38.9680340117755 -3.75740124028773 0.000209930492481073 GOLGA1 other 3.7362923312024e-09 1 0.0220423434404004 4.85476796901695 -3.75740124028773 1.04594781962531e-17 86.0966844191725 15.7296645107603 5.47352325030681 1.01079698494505e-07 -145.417972586865 30.3587775096022 -4.78998116906618 2.7591796578153e-06 XPA ts 1.47394966741598e-13 0.0429162803976591 0.00119486311590354 5.47352325030681 -4.78998116906618 1.3867286482478e-25 374.778640932206 42.7681136176282 8.76303884438172 2.18390770000667e-16 -305.792548893983 82.543886739273 -3.70460564644689 0.000256949050229063 NCBP1 essential 2.13181795095134e-21 1 3.25140178376993e-12 8.76303884438172 -3.70460564644689 1.89414401978529e-27 1387.90903750924 153.746254547558 9.02727056079223 3.41747580120526e-17 -1189.13227482393 298.198396156606 -3.98772189974969 8.59447700555809e-05 ANP32B other 2.93781737468698e-23 1 5.12450496390728e-13 9.02727056079223 -3.98772189974969 1.41103239660214e-26 136.258974137185 19.0473409750693 7.15370057770962 7.83697882918571e-12 -216.609286970562 36.3612576969273 -5.95714506841349 7.91680741839458e-09 PDCL other 2.17849291711404e-22 0.000125813903493127 1.08087612012129e-07 7.15370057770962 -5.95714506841349 2.56709223722065e-09 2066.73243933052 465.732172899675 4.43759860192377 1.32105068420877e-05 -2225.46610566865 895.573864730575 -2.48496097676786 0.0135559008547442 RPL35 essential 2.71007927483384e-05 1 0.134350854584032 4.43759860192377 -2.48496097676786 0.0121463409914657 304.431427460541 101.669046593772 2.99433738841797 0.00300549909823553 241.372239502696 196.457137727582 1.22862545130529 0.220282076533953 CTSV other 1 1 1 2.99433738841797 1.22862545130529 0.0805993596556151 31.4042182931922 17.7487152672928 1.76937980131237 0.0779509973163065 -18.478398069516 33.0266398070881 -0.559499791000542 0.57628109055905 LMX1B other 1 1 1 1.76937980131237 -0.559499791000542 1.81182865521614e-14 222.954614756101 50.3489648214621 4.42818666772396 1.37596335909583e-05 -452.052089703524 96.817913028426 -4.6690955791497 4.74981771161041e-06 ARPC5L other 2.35827617762933e-10 0.0735651767174221 0.139646521314635 4.42818666772396 -4.6690955791497 0.66221423944979 -66.8964123078612 82.6238388006491 -0.809650256861893 0.418851541102406 -186.280170972956 350.938579291399 -0.530805622308855 0.595988206977408 ENPP2 other 1 1 1 -0.809650256861893 -0.530805622308855 9.44799041535422e-14 91.457281146396 11.2831584496677 8.10564537885133 1.81632725886556e-14 2.38244513247668 47.9243721149277 0.0497125998179657 0.960388035049929 DSCC1 other 1.20537461719089e-09 1 2.63639901624336e-10 8.10564537885133 0.0497125998179657 4.44020453521813e-17 455.504586063748 49.1632583662634 9.26514232783893 6.48291819851248e-18 118.948326552584 211.746737578157 0.561748095451434 0.574755386519218 DERL1 other 6.18209677438421e-13 1 9.78531672883473e-14 9.26514232783893 0.561748095451434 0.158765397414162 298.042313575837 161.812050736858 1.84190430946654 0.0666323732384465 -203.723281944467 686.528422730072 -0.29674413352667 0.766899690598359 MYC og 1 1 1 1.84190430946654 -0.29674413352667 0.685879844257616 14.0779316108174 18.4946202837392 0.761190627049261 0.447205062262296 -23.446631229964 78.5545172086379 -0.298475912819763 0.765568687144054 NOV other 1 1 1 0.761190627049261 -0.298475912819763 0.0437762021783024 -122.774598565707 99.9390057345916 -1.22849529733926 0.220355110351292 -865.421690218937 347.145883018897 -2.49296256286533 0.0132813880495726 IL33 other 1 1 1 -1.22849529733926 -2.49296256286533 3.43811909780993e-30 191.702085050814 16.856832526074 11.3723669470104 1.18212038015348e-24 -134.891986634663 58.5535144076398 -2.30373852021192 0.0220144324913403 RANBP6 other 5.38787643817794e-26 1 1.84517170138156e-20 11.3723669470104 -2.30373852021192 1.75742255918749e-31 200.53786355434 18.2721413317773 10.9750608816484 2.7145286877143e-23 -91.958690870206 44.630972271278 -2.06042320367252 0.0403492454769831 POLR1E essential 2.76178955176315e-27 1 4.21973484505188e-19 10.9750608816484 -2.06042320367252 1.41565709139356e-27 328.442240406528 29.8514987479114 11.0025377010428 4.42065842151933e-23 -115.260534134957 85.5117732761411 -1.34789081922964 0.17895911421578 PLAA other 2.19653354300624e-23 1 6.86749285783027e-19 11.0025377010428 -1.34789081922964 0.000427964489589653 77.0908965747124 20.7851682518985 3.70893781760324 0.000253706880428419 28.7757053590626 55.0820177347026 0.52241560027191 0.601819091854679 IL11RA other 1 1 1 3.70893781760324 0.52241560027191 3.72291634575729e-33 489.583561022623 53.7594817620078 9.10692486192483 2.12634095860943e-17 -666.068165657461 152.110135506661 -4.37885459400104 1.71901390380039e-05 UBAP2 other 5.86843303581722e-29 0.263095077976649 3.19525255850239e-13 9.10692486192483 -4.37885459400104 2.59802425748514e-37 385.912831674957 30.4038659232697 12.6928869061877 5.51637095914944e-29 -98.2360074626878 81.4299362032609 -1.20638688967503 0.228777691731842 APTX other 4.11475081900496e-33 1 8.68662934937262e-25 12.6928869061877 -1.20638688967503 7.97212740877772e-24 233.443075800206 30.9630541064772 7.5394072883583 7.66383760984319e-13 -324.718673972373 87.3864733284434 -3.71589173477585 0.000247349538710791 RNF38 other 1.21176336613421e-19 1 1.08190395538156e-08 7.5394072883583 -3.71589173477585 0.503996790968041 -109.555120782398 117.121978633115 -0.935393357087827 0.350440439202237 48.4677007826723 310.380691943808 0.15615565671671 0.876029670232686 CCL21 other 1 1 1 -0.935393357087827 0.15615565671671 0.922950784522608 2.38683196116692 5.97812492743018 0.399260970645682 0.690021285827161 3.79360395945368 17.035767458889 0.22268465266437 0.823951841008817 SIT1 other 1 1 1 0.399260970645682 0.22268465266437 0.325598227684558 4.223079068516 5.66413576021069 0.745582247195098 0.456583114733336 -17.2219168463156 18.3541587753478 -0.938311423427753 0.348942028576568 DMRT1 other 1 1 1 0.745582247195098 -0.938311423427753 1.2028101323208e-06 106.417294553972 26.3644008321941 4.03640102543214 7.12286697020108e-05 -77.5155835112942 68.250924018901 -1.13574408882475 0.257097590852073 DNAJB5 other 0.0106448696710391 1 0.678880450929865 4.03640102543214 -1.13574408882475 6.18317391444083e-06 22.0269102243378 4.99799868986431 4.40714605808266 1.5226271682305e-05 2.34985318011505 13.9985647573345 0.16786386467826 0.86681841417995 SPAG8 other 0.0514811060116344 1 0.154013738066515 4.40714605808266 0.16786386467826 2.03631136585481e-18 333.997775349691 44.7245246878405 7.46788876306375 1.20139877054197e-12 -213.381270774069 119.166327278185 -1.79061716214469 0.0745047860395081 DCTN3 essential 2.9074453681675e-14 1 1.68988751064434e-08 7.46788876306375 -1.79061716214469 3.87872504890113e-26 127.517003640871 12.3173022874271 10.3526730663283 2.44998094206924e-21 -15.3765934188889 35.0772652194982 -0.438363519010644 0.661477250875106 CD72 other 5.97944253538599e-22 1 3.77370564506925e-17 10.3526730663283 -0.438363519010644 5.71801238014026e-20 185.098451696719 22.6725629421052 8.16398446745396 1.30840934682639e-14 -80.219498723921 63.1840218906838 -1.2696168481125 0.205330758413194 TMEM8B other 8.35344428614691e-16 1 1.90321223589366e-10 8.16398446745396 -1.2696168481125 3.52306236576898e-36 615.054262579547 49.9843226026094 12.3049434413549 9.0995797907495e-28 -215.584314279127 121.586495097565 -1.77309424131468 0.0773748580505595 GRHPR other 5.5738369688831e-32 1 1.43008995991419e-23 12.3049434413549 -1.77309424131468 3.37433663559384e-12 310.922631082355 45.5342887083627 6.82831861223853 6.17262037722307e-11 17.7001617468657 103.576745535508 0.170889340607808 0.864445242005313 ALDH1B1 other 4.07586122213381e-08 1 8.31019881385542e-07 6.82831861223853 0.170889340607808 8.90143085789866e-36 203.912589666975 17.8211111668571 11.4421927879673 6.66062407212635e-25 -123.364562800962 49.9139744119616 -2.47154357580867 0.0140820752780288 HINT2 other 1.40749424725094e-31 1 1.04085572375119e-20 11.4421927879673 -2.47154357580867 1.72437401497318e-15 228.875077831118 39.731669090317 5.76052008564869 2.3202066402635e-08 -315.729127444081 111.281810418579 -2.8372033691444 0.00490273193663695 ARHGEF39 other 2.30876436864759e-11 1 0.000282879593580925 5.76052008564869 -2.8372033691444 3.14675861972262e-06 15.7873889519739 7.20574478434493 2.19094478426065 0.0293610865157547 -50.9881771424755 16.3484950928318 -3.11883001175024 0.00202413034029153 IGFBPL1 other 0.026863878336572 1 1 2.19094478426065 -3.11883001175024 2.29130362070524e-11 193.000700724923 33.4143448062263 5.77598339408289 2.13863675661523e-08 -325.366294771136 119.124232625746 -2.73131912457597 0.00673171908636326 DENND4C other 2.67899219332857e-07 1 0.000261042002512455 5.77598339408289 -2.73131912457597 1.58817809169251e-15 15456.1673068974 1809.50762102994 8.54164255915099 1.05332347836057e-15 1866.27632471563 6451.00803369529 0.289299953583624 0.772578049631515 RPS6 essential 2.1289527319138e-11 1 1.55438945701669e-11 8.54164255915099 0.289299953583624 1.39911255048007e-25 1118.66216042885 98.4106425793993 11.3672884467379 9.63433401060567e-25 87.0030213510182 239.925462449268 0.362625210608544 0.717167522113593 CNPY3 other 2.15071581259797e-21 1 1.50449759909618e-20 11.3672884467379 0.362625210608544 2.70747334957594e-05 196.560834314015 97.3396045995406 2.0193305193983 0.0444300032785665 -664.966286185978 207.791347639318 -3.20016349930133 0.00153569115281348 FOXP4 other 0.213132302078618 1 1 2.0193305193983 -3.20016349930133 3.40970885327407e-15 417.468661726412 53.1439426452201 7.85543264099468 9.37539582263074e-14 -53.7608563660873 104.335567809615 -0.51526873811802 0.606785292391255 PPIL1 other 4.53184403688657e-11 1 1.34593182429687e-09 7.85543264099468 -0.51526873811802 2.01961685607846e-27 324.603702436071 27.9944381430136 11.5952926355509 1.57620426842549e-25 -26.7650039093986 68.1653948499549 -0.392647969960616 0.694887028954258 KLC4 other 3.13181985872087e-23 1 2.46581395752484e-21 11.5952926355509 -0.392647969960616 0.00338793944941977 269.028596114898 85.1006883346028 3.16129753330688 0.00174901198122461 -26.4443821532975 160.053035106281 -0.165222622212303 0.86889194108919 KIF13A other 1 1 1 3.16129753330688 -0.165222622212303 7.99238605718246e-11 69.2631495999412 11.6581068224601 5.94120045859431 8.62929010955481e-09 -31.4546672508175 21.1206610298563 -1.48928422298682 0.137571097165562 ZSCAN9 other 9.13289954754239e-07 1 0.000107451920444176 5.94120045859431 -1.48928422298682 3.79657496325727e-05 499.473608339568 130.154192590884 3.83755297003434 0.000154930478592889 -219.46179374589 255.56109441178 -0.858744928491641 0.391245811716051 PIM1 og 0.294348456901336 1 1 3.83755297003434 -0.858744928491641 0.346080593853656 35.9150417523557 24.6160047929249 1.45901181180621 0.145715684899488 25.1914087630876 46.4891195867177 0.54187751859007 0.58834649753133 GMPR other 1 1 1 1.45901181180621 0.54187751859007 3.04709357991754e-19 385.038063521266 42.64259485993 9.02942386095448 3.53761501827765e-17 -47.6984762443901 83.2014233670225 -0.573289185618617 0.566931429509136 CMTR1 essential 4.40518318848679e-15 1 5.30323867390003e-13 9.02942386095448 -0.573289185618617 2.07096570845128e-07 375.246922743773 92.6492445069672 4.05018869544645 6.69306858569407e-05 -398.011606203097 173.496680602606 -2.29405891121769 0.0225551199605452 TFAP2A other 0.00194401551052322 1 0.639121119247927 4.05018869544645 -2.29405891121769 3.70040126226961e-32 769.022443989061 63.1806018251599 12.1718125781261 1.82875810159219e-27 -346.644123916901 154.191639251985 -2.24813826222059 0.025374372427302 YIPF3 other 5.82221134605501e-28 1 2.8722474743607e-23 12.1718125781261 -2.24813826222059 2.5445347295065e-12 629.658001033004 85.4648733817636 7.3674478896187 2.12032507074069e-12 97.1120191575373 159.203238434641 0.609987712011308 0.542382978064023 TMEM14B other 3.08804734772908e-08 1 2.96485054641671e-08 7.3674478896187 0.609987712011308 1.72579955842601e-12 436.229590621753 70.9276188958489 6.15034872751501 2.77406146272118e-09 -418.320867249741 172.450080127278 -2.42575049510558 0.0159324661990831 TMEM63B other 2.10909964035242e-08 1 3.52499990067981e-05 6.15034872751501 -2.42575049510558 4.1307241323997e-17 56.338786444907 6.9460125696478 8.11095371337108 1.75359808217995e-14 -20.4407293610841 14.8313214705785 -1.37821362726398 0.169274142190905 FRS3 other 5.75451178884602e-13 1 2.54657513494172e-10 8.11095371337108 -1.37821362726398 4.67236990478778e-30 456.628994959901 36.4512722051958 12.5271072128674 1.08805881774134e-28 3.91361602002971 88.9589724025269 0.0439934940156587 0.964942107729108 TJAP1 other 7.31973469284054e-26 1 1.71227816147955e-24 12.5271072128674 0.0439934940156587 0.331100367333023 32.023758191446 41.3177282977264 0.775060960774268 0.438984411901058 -66.9643707077354 71.8906541954068 -0.931475328152096 0.352442964621331 KIAA0319 other 1 1 1 0.775060960774268 -0.931475328152096 0.214009601910199 -34.2613929387881 28.6197808002127 -1.19712282836679 0.232349022765862 36.7329677989149 50.4248570552511 0.728469448285518 0.466981864184671 IRF4 other 1 1 1 -1.19712282836679 0.728469448285518 0.00606755405568769 285.108923239829 153.646127156373 1.85562062979732 0.0646137025514631 -468.58804575872 276.551369465399 -1.69439784971793 0.0913601080372996 SLC22A23 other 1 1 1 1.85562062979732 -1.69439784971793 0.000494218928871541 328.041531726476 87.08783192533 3.76678950978757 0.000203620261293332 57.3565186813423 156.751488816966 0.365907329584063 0.714725056170772 TUBB2A other 1 1 1 3.76678950978757 0.365907329584063 4.67587800473373e-17 394.980500076393 46.6239532917807 8.47162182075246 1.71566895282406e-15 -88.5112085475603 108.87694345894 -0.81294722037214 0.416980835950788 LRRC1 other 6.50601665578651e-13 1 2.52529313166174e-11 8.47162182075246 -0.81294722037214 0.492648531256785 -23.5442471388535 22.2642162518442 -1.05749274407552 0.29125710898224 -36.6799762643126 39.8552810874742 -0.920329132387939 0.358244166332798 FOXF2 other 1 1 1 -1.05749274407552 -0.920329132387939 2.62045369252421e-13 156.305297601566 23.0680275696256 6.77584145977778 7.92861912819443e-11 -54.7104342626699 41.5206991110996 -1.3176664996964 0.188749052260136 BPHL other 3.29653074519545e-09 1 1.06291068032575e-06 6.77584145977778 -1.3176664996964 7.98961904720498e-08 104.322185155284 31.8763003937911 3.27271935157205 0.00120607187128 -184.71269493617 57.3749217799772 -3.21939776483725 0.00144406041224796 RIPK1 other 0.0007697997951982 1 1 3.27271935157205 -3.21939776483725 0.000703882376719107 653.134542011125 169.43268903869 3.85483194368698 0.000145275229065074 532.760659671509 304.965982892404 1.74695110129536 0.0817999631313263 TUBB2B other 1 1 1 3.85483194368698 1.74695110129536 6.51650642230864e-13 584.310061592591 92.5155569772812 6.31580331658252 1.09638174100991e-09 -255.427370628162 170.412382662977 -1.49887799605101 0.135069248263626 UQCC2 other 8.0908943739384e-09 1 1.41520955129559e-05 6.31580331658252 -1.49887799605101 1.50971626869824e-10 2500.80479443313 475.178253034626 5.26287720126556 2.87998565150823e-07 -1922.96449629786 904.177754281792 -2.1267549297597 0.0343406292093067 HMGA1 other 1.70220509295727e-06 1 0.00331255949636476 5.26287720126556 -2.1267549297597 1.74604964405602e-09 309.832244472506 50.5500700120203 6.12921494270593 3.07805670267655e-09 0.369748185384706 99.8392177392044 0.00370343632249349 0.997047796830695 TCF19 other 1.86233655035015e-05 1 3.90543834435601e-05 6.12921494270593 0.00370343632249349 1.12613113554463e-15 1323.97204359994 165.386698742116 8.00531151337861 3.52049293383929e-14 -290.297575001947 325.228003728383 -0.892597106257775 0.372864873385444 FLOT1 other 1.5152094428753e-11 1 5.08535204293085e-10 8.00531151337861 -0.892597106257775 0.00139085994765108 394.700605211373 217.28068864067 1.81654710172662 0.0703911794221242 -1026.23350544543 427.27598502659 -2.40180478521762 0.0169879058635132 IER3 other 1 1 1 1.81654710172662 -2.40180478521762 1.65991912516137e-11 441.671860836329 66.74325714072 6.61747537890034 1.94692398107752e-10 -114.772453995124 131.248621849895 -0.874465974403798 0.382638841733816 MDC1 other 1.95256286692732e-07 1 2.57928489013149e-06 6.61747537890034 -0.874465974403798 4.02507212762054e-06 44.676082760023 9.53954217177625 4.68325229403587 4.46306331281368e-06 -3.00514670809553 17.282517621295 -0.173883618923245 0.862086267635294 PGBD1 other 0.0341004110652013 1 0.0471299485833124 4.68325229403587 -0.173883618923245 2.03129535370716e-08 105.168482699118 19.4385028037193 5.41031805592535 1.38014214994048e-07 -36.2177633757038 38.1220404273818 -0.950047871773669 0.342931305170836 ATAT1 other 0.000203088909463642 1 0.00161904475609518 5.41031805592535 -0.950047871773669 3.49568960001509e-08 208.292463566689 38.386612859081 5.42617459715291 1.27750644400373e-07 -55.138898121011 72.1370399308089 -0.764363192250446 0.445315865691028 TPMT other 0.000344360382497486 1 0.00150170882492639 5.42617459715291 -0.764363192250446 0.0685610787737737 85.4075016869611 76.557066555865 1.11560572432119 0.265579207840342 -225.487694420105 143.867868399844 -1.56732491367301 0.118205654239517 RNF144B other 1 1 1 1.11560572432119 -1.56732491367301 1.00790435376362e-12 209.88323233817 28.9444829409403 7.25123446725325 4.33048764361323e-12 -20.5691974707826 56.9184612633849 -0.361380069211649 0.718096924343636 NRM other 1.24214132557828e-08 1 6.01169641050908e-08 7.25123446725325 -0.361380069211649 5.67170918851524e-19 1134.57600380271 136.528994635236 8.31014691666012 4.70300468586035e-15 -483.131872273796 267.267101365434 -1.80767430710902 0.0717700158673582 MTCH1 other 8.17350011156931e-15 1 6.8870800619739e-11 8.31014691666012 -1.80767430710902 3.54608958422603e-14 453.600469996753 62.0365922492774 7.3118211937574 2.92781348785107e-12 -157.505657533798 122.035616892259 -1.29065318424911 0.197915936219921 VARS2 essential 4.58438461448741e-10 1 4.08225034611075e-08 7.3118211937574 -1.29065318424911 4.34043846161387e-22 191.376431848146 19.7728326059518 9.67875648684447 3.19332667027682e-19 -55.6898052677664 44.6603613625608 -1.24696271075074 0.213487798512406 TAF8 essential 6.50197681549758e-18 1 4.86758784350296e-15 9.67875648684447 -1.24696271075074 3.80048811058624e-05 150.183405694313 35.8103812544179 4.19385106869772 3.71847792814403e-05 -27.1156946262174 67.3503389954621 -0.402606653962712 0.687555012299988 FAM8A1 other 0.294613838332645 1 0.363704326151768 4.19385106869772 -0.402606653962712 0.00424075456191301 6.17602135181592 2.1115117146993 2.9249287649325 0.00373794800956503 -1.7810585663225 3.93330604342226 -0.452814641591645 0.651045862314367 C6orf52 other 1 1 1 2.9249287649325 -0.452814641591645 0.283722647983954 723.319853986112 541.315360426086 1.33622636057614 0.182604519675066 188.734892737903 792.994055593441 0.238002909866282 0.812060024520737 FGFBP1 other 1 1 1 1.33622636057614 0.238002909866282 0.579283288665001 19.5352668931959 393.499828189582 0.0496449184821095 0.960442192132034 470.199570697106 576.453297733432 0.815676781702685 0.415406670758284 FGFBP2 other 1 1 1 0.0496449184821095 0.815676781702685 3.38387653192847e-10 -48.0853711105881 43.1906753008235 -1.11332760545356 0.266557924824403 -367.711857456361 63.1182289508857 -5.82576323145077 1.6137874833145e-08 CPEB2 other 3.75102713564271e-06 0.000256204900851009 1 -1.11332760545356 -5.82576323145077 9.85152189631265e-05 62.1092865512496 79.8620062742163 0.777707566448926 0.437422345731691 -355.041724527352 118.555380741085 -2.99473311382411 0.00300172978460734 FHDC1 other 0.730884409487436 1 1 0.777707566448926 -2.99473311382411 0.00202974994317115 -23.8090171868167 59.243214758839 -0.401885976035162 0.688082388828499 -270.805394935255 87.5516662325899 -3.09309241717722 0.00218620180150163 TLR2 other 1 1 1 -0.401885976035162 -3.09309241717722 0.44606565084533 7.8941903053252 8.22840366052379 0.959382965519546 0.338227356318264 -0.230124511173783 11.8279052008376 -0.0194560665871321 0.984491707404326 TTC29 other 1 1 1 0.959382965519546 -0.0194560665871321 0.866992736443315 7.64625960341594 15.7357576238176 0.485916203478033 0.627420690240278 15.7672541845135 40.302416110566 0.391223547026497 0.695940555841448 MYO7A other 1 1 1 0.485916203478033 0.391223547026497 1.4567726782227e-09 278.425549414061 44.2431450567391 6.29307769727938 1.28851528319791e-09 46.1112876365233 104.086073823745 0.443011115152699 0.658120485335337 FCHSD2 other 1.5607862474478e-05 1 1.65922113017395e-05 6.29307769727938 0.443011115152699 0.0529487376823895 137.477388289676 60.7394381814449 2.26339578379034 0.0244024435225749 9.18239599383694 145.384923241379 0.0631592037820294 0.949686290059835 ARRB1 other 1 1 1 2.26339578379034 0.0631592037820294 0.568429239067791 -81.7827308407102 129.228363023456 -0.632854343483914 0.527360442814182 -345.365164229559 334.944602398712 -1.03111129946929 0.303404596335106 SLCO2B1 other 1 1 1 -0.632854343483914 -1.03111129946929 9.0903308415909e-27 636.273166023167 58.4515805815007 10.8854740914319 3.93047275108936e-23 -116.517463892463 138.163077474943 -0.843332864481062 0.39978605134713 THAP12 other 1.40509243818471e-22 1 6.10677551336754e-19 10.8854740914319 -0.843332864481062 8.46506117645515e-11 71.1763195569327 11.7687822716253 6.04789160969862 4.87200281016614e-09 -18.4053340144238 25.5051057086802 -0.721633316272039 0.471144402013712 ANKRD42 other 9.66286733292355e-07 1 6.13141553659408e-05 6.04789160969862 -0.721633316272039 1.10218014412855e-05 162.582570900212 47.8745593670821 3.39601184950021 0.000789891787092827 -266.604613104629 125.294795515117 -2.12781873348013 0.0342858865671146 IL18BP other 0.0899158561580073 1 1 3.39601184950021 -2.12781873348013 4.0653227273811e-10 1686.93617160691 289.306456863493 5.83096620067099 1.61672034644822e-08 -1046.54124257589 757.157743760635 -1.38219710648134 0.168088388257726 NUMA1 other 4.49014895239242e-06 1 0.000198775766595809 5.83096620067099 -1.38219710648134 1.1615472945165e-13 182.264113865345 35.2822636570021 5.16588492272586 4.65492260426975e-07 -261.793028847769 76.4631245139931 -3.42378146997981 0.000713482660049264 CCDC90B other 1.47795277754279e-09 1 0.00527588927967933 5.16588492272586 -3.42378146997981 0.101818338733309 -43.4958899927198 59.7925541991598 -0.727446595571777 0.467582725168569 -261.332594435322 122.94115025311 -2.1256722740701 0.0344382820179719 SYTL2 other 1 1 1 -0.727446595571777 -2.1256722740701 0.00014862846429194 90.2359893092791 34.1388446864677 2.6432057129645 0.00869070761203993 -137.548024722292 73.9556415501241 -1.85987196972752 0.0639870675223956 RAB30 other 1 1 1 2.6432057129645 -1.85987196972752 2.72974695198217e-09 365.740259282744 73.0502169021109 5.00669641779223 1.00073114353327e-06 -203.096366572905 150.200602942479 -1.35216745202203 0.177453241534613 CREBZF other 2.87824518617e-05 1 0.0110991091129275 5.00669641779223 -1.35216745202203 0.591397900256947 -9.01185397828285 145.650838494576 -0.0618729975840025 0.950709578801223 -371.375185624835 381.957357936266 -0.972294885563648 0.331770895292339 LRRC32 other 1 1 1 -0.0618729975840025 -0.972294885563648 5.5593927031566e-06 409.069671761465 141.970135367605 2.88137833145158 0.00427613944171108 -754.075134051614 307.55265851838 -2.45185698502603 0.0148434499118614 PRCP other 0.0465098793546081 1 1 2.88137833145158 -2.45185698502603 2.09641281534306e-25 291.612501117633 26.7272483367276 10.9106817673 3.34109228721763e-23 -3.21017494709904 67.451304543909 -0.047592481254522 0.962076208155305 NARS2 other 3.2186225953962e-21 1 5.19305974202236e-19 10.9106817673 -0.047592481254522 8.73973859745854e-22 133.212681224487 15.3967054044536 8.65202507453022 5.19288205313381e-16 -126.734108628721 40.2954529662774 -3.14512182639521 0.00185155070304334 RNF121 other 1.30510516475848e-17 1 7.6958512027443e-12 8.65202507453022 -3.14512182639521 6.84353724910612e-09 252.450386130588 43.0892983083286 5.85877227157799 1.4575986493092e-08 -45.3458867255462 138.599252756091 -0.327172663804663 0.74380998406819 MRPL15 essential 7.04268418305511e-05 1 0.00017960530556788 5.85877227157799 -0.327172663804663 0.513611689202401 39.4138165387756 38.2233512131106 1.03114497520188 0.30340249385743 -20.6908489331107 126.755208557178 -0.163234703872363 0.870456665512074 PI15 other 1 1 1 1.03114497520188 -0.163234703872363 0.000563391647324031 519.484486923185 133.671254897118 3.8862842076482 0.000128907085548298 387.502060377423 410.676255132626 0.943570648496054 0.346255075374402 GGH other 1 1 1 3.8862842076482 0.943570648496054 0.245409836257273 5.53387657416371 8.35506595768497 0.662337868089917 0.508319662153468 -32.6512621801814 26.621202855454 -1.22651340577918 0.221074062482623 SLCO5A1 other 1 1 1 0.662337868089917 -1.22651340577918 0.708185493073911 256.66781582996 327.952316313169 0.782637606330738 0.434525821719658 553.788996670131 1044.93312006216 0.529975542010944 0.596564431310512 SULF1 other 1 1 1 0.782637606330738 0.529975542010944 8.58634685891427e-10 146.193722548122 28.0470690550758 5.21244206519559 3.81149802082002e-07 -197.646032854442 87.3444824949848 -2.2628336353792 0.0244744190530121 TGS1 essential 9.31189316849252e-06 1 0.00434701349274523 5.21244206519559 -2.2628336353792 0.000292311683390255 464.877665258448 148.17792460074 3.13729367252945 0.00189984500486949 -615.848314798709 450.086953503914 -1.36828741647441 0.172394357266894 SDCBP other 1 1 1 3.13729367252945 -1.36828741647441 1.41252799849106e-11 95.5946070139448 26.9089932558553 3.55251517977707 0.000450161498823053 -117.231297699756 39.260640211985 -2.98597519212051 0.00308617181062716 NEK1 other 1.66748930221869e-07 1 1 3.55251517977707 -2.98597519212051 4.12037397878379e-07 157.202371362002 84.8199195172125 1.8533661934223 0.0649207082377784 -380.301785760982 124.880292054405 -3.04533068833071 0.0025540017545929 DDX60 other 0.00378909591088957 1 1 1.8533661934223 -3.04533068833071 1.97800755225171e-05 1136.93339797898 337.236044375968 3.3713282341536 0.000856176722986841 -781.050389575038 609.675125680082 -1.2810927601873 0.201248251065204 SORL1 other 0.157904342896254 1 1 3.3713282341536 -1.2810927601873 0.000160692712479763 -237.457598720538 620.002980935547 -0.38299428554719 0.702023137759897 -4244.92894043494 1109.25921695143 -3.82681421579822 0.000161102022303225 TMPRSS4 other 1 1 1 -0.38299428554719 -3.82681421579822 9.12213568616172e-16 142.86771799629 19.9402469943777 7.16479179202605 7.32131782149783e-12 -22.6864036715165 34.5467867002872 -0.656686361841226 0.511937805022709 BUD13 essential 1.23030243999263e-11 1 1.0103418593667e-07 7.16479179202605 -0.656686361841226 0.30780474348859 24.820728361187 43.7708060979762 0.567061257807966 0.571143693677752 -75.3023474959126 79.1396621564196 -0.951512117237466 0.342195456844528 TRPC6 other 1 1 1 0.567061257807966 -0.951512117237466 0.189605042010966 -440.772572959579 247.943033062563 -1.77771711314171 0.0765716785043983 -556.249137059902 542.297987095079 -1.02572598515358 0.305935448962698 MMP7 other 1 1 1 -1.77771711314171 -1.02572598515358 0.00995720014656771 25.6152738325065 8.37935640432162 3.05695003249838 0.00246197908801805 20.6121063257364 14.8389444543267 1.38905475313147 0.165969231055135 C11orf70 other 1 1 1 3.05695003249838 1.38905475313147 2.19338656611051e-34 601.147607945006 42.9466085723368 13.9975571512816 8.12794968236316e-34 126.416003767465 94.055314352076 1.34406019094523 0.180061383072362 DCUN1D5 other 3.46204135594883e-30 1 1.28722339119585e-29 13.9975571512816 1.34406019094523 3.07192640835724e-09 572.55506469754 144.019357332923 3.97554242221753 9.03689336279815e-05 -616.231976061838 255.042886433245 -2.41618962473251 0.016352673781819 YAP1 other 3.22828746254262e-05 1 0.851275354775586 3.97554242221753 -2.41618962473251 3.16001201807844e-06 1223.01722432805 930.629816214589 1.31418229141075 0.189892044760381 -6182.82172499807 1684.22280341904 -3.67102363918047 0.000290738230850326 TRIM29 other 0.0269738625863175 1 1 1.31418229141075 -3.67102363918047 2.62319720173039e-14 210.503556949438 36.1608319204747 5.82131399555132 1.64656212651328e-08 -139.515107473418 64.992250757303 -2.14664218961122 0.0327094482075699 SLC37A4 other 3.40333604952501e-10 1 0.000202313088484687 5.82131399555132 -2.14664218961122 0.890645219299919 -15.2883628235855 64.0903212446576 -0.238544019232232 0.811638795955896 -55.8227032447777 115.967282965862 -0.481365966478756 0.630643443441809 POU2F3 other 1 1 1 -0.238544019232232 -0.481365966478756 3.46055298119432e-10 593.912559236907 108.283068648851 5.48481463120422 9.48942683759878e-08 -159.105021827715 194.644224181124 -0.817414554668012 0.414409616928129 RDX other 3.83394664786519e-06 1 0.0011235481375717 5.48481463120422 -0.817414554668012 4.95965597204698e-14 268.750216817013 47.227208563645 5.69058017593473 3.28133301480867e-08 -169.215417211086 83.7232339488375 -2.02112853541338 0.0442495361276361 PPP2R1B other 6.38357320162167e-10 1 0.000397205361442589 5.69058017593473 -2.02112853541338 1.30400401458799e-12 105.264480842074 21.8776038532275 4.81151782198234 2.49007038903167e-06 -112.690636055317 39.3260856206688 -2.86554418719187 0.00448918981543144 FDX1 other 1.59962172469508e-08 1 0.0268379786529833 4.81151782198234 -2.86554418719187 2.19090044775013e-07 85.7584658484681 24.3349787123085 3.5240822218222 0.00049865334539442 -81.0252268495536 43.1404518250302 -1.87817288465538 0.0614311619342381 C11orf1 other 0.00205243553945232 1 1 3.5240822218222 -1.87817288465538 0.464576018030458 119.120055218774 240.35687489604 0.495596621774584 0.62057773945303 -307.905365629846 429.744074501188 -0.716485424463939 0.474304133484005 FXYD6 other 1 1 1 0.495596621774584 -0.716485424463939 0.0566669947438734 26.4613199845353 11.3732142774447 2.32663513928628 0.0207221271353245 12.9479454998447 20.4439207080267 0.633339645793139 0.527045986320146 ARHGAP20 other 1 1 1 2.32663513928628 0.633339645793139 0.0248503438937135 63.8902484732629 24.4030168893168 2.6181290929333 0.0093349358291075 30.0529927802581 43.7776262728625 0.68649205859039 0.492985526876618 FXYD2 other 1 1 1 2.6181290929333 0.68649205859039 0.300482508394758 56.5849473087511 632.104289794439 0.0895183725570864 0.928736319922258 -1966.60092286234 1381.92424958384 -1.42308880060146 0.155864828453639 MMP13 other 1 1 1 0.0895183725570864 -1.42308880060146 5.48227571720254e-06 188.859511420288 71.5022633912233 2.64130815533693 0.00873472835367584 -294.171798894193 127.841876872013 -2.30105976298125 0.0221418682382865 TMPRSS13 other 0.0458866477529853 1 1 2.64130815533693 -2.30105976298125 0.0873105856392352 76.6396290714145 43.4429637348693 1.76414366062001 0.0788344085567582 -61.5579933341521 95.9322651573023 -0.641681849513447 0.521622142255503 CASP1 other 1 1 1 1.76414366062001 -0.641681849513447 0.0907715139851493 5.41591719628676 2.46861259532781 2.19391135188127 0.0290909904446182 3.329967618802 5.45127628747763 0.610860180844514 0.541804142114608 CASP5 other 1 1 1 2.19391135188127 0.610860180844514 2.23868388636284e-09 37.3521548142861 7.73118329652715 4.83136324436451 2.27618439092669e-06 -19.9541188147663 13.8033520896395 -1.44559949533878 0.149449257846969 ALKBH8 other 2.37390039309915e-05 1 0.0245941723439629 4.83136324436451 -1.44559949533878 2.86829227656347e-13 112.08709013478 16.514234545436 6.78730157467439 7.13950689916497e-11 -36.4615767658471 31.8947543524527 -1.14318412247132 0.253967324772329 MAP2K5 other 3.60314875781903e-09 1 9.58407406143906e-07 6.78730157467439 -1.14318412247132 0.00724286163868732 36.8280762022409 122.162729028223 0.301467366480758 0.76328932594815 -579.846029287102 219.564382137548 -2.64089295195362 0.00874872540205959 SQOR other 1 1 1 0.301467366480758 -2.64089295195362 1.65073147410625e-11 310.768374254947 55.228613339233 5.62694508272553 4.5567845359583e-08 -149.660078220931 99.000866600193 -1.51170472906385 0.13176991450897 CTDSPL2 other 1.94241572558083e-07 1 0.0005485001545933 5.62694508272553 -1.51170472906385 1.13837607407518e-05 254.904360635872 68.48267004218 3.72217322249367 0.000240023249085104 -186.397396058023 133.69568932206 -1.39419151809008 0.164397576869816 SLTM other 0.0927434987549051 1 1 3.72217322249367 -1.39419151809008 0.944067681269066 -9.91712175391844 884.830209566358 -0.0112079375757058 0.991065762931864 -457.935510225916 1541.17689543538 -0.297133646100079 0.766591266287792 THBS1 other 1 1 1 -0.0112079375757058 -0.297133646100079 3.0152829854451e-08 303.989821252465 71.2417946799114 4.26701520670961 2.7440558867261e-05 -190.626002158789 125.15510109939 -1.52311811891236 0.128899505918106 MAPKBP1 other 0.000298603474048628 1 0.271853616697955 4.26701520670961 -1.52311811891236 2.666341942558e-07 511.527591593015 102.572880743125 4.98696719724622 1.09446887670501e-06 45.3752838905677 179.371141834565 0.252968696226607 0.800483481336733 NUSAP1 other 0.00248369751949278 1 0.0120993534319739 4.98696719724622 0.252968696226607 2.82418217839863e-12 50.4005971093579 10.2492071448012 4.91751180333234 1.5184469769735e-06 -45.445531895262 17.9229829087664 -2.53560091680019 0.0117857588348353 NDUFAF1 other 3.41895494516938e-08 1 0.0166269943978598 4.91751180333234 -2.53560091680019 3.98704333348765e-08 299.084044857906 54.9417016756155 5.44366184039486 1.17267265716307e-07 -26.5387360186656 104.17599009682 -0.254749064482142 0.799110842467834 KIF23 essential 0.000391487784915152 1 0.00138129112287238 5.44366184039486 -0.254749064482142 0.513439814975868 -107.526564172494 99.5934771278369 -1.07965468495969 0.281259478022023 -156.054366036764 192.480914206123 -0.810752415014248 0.418221923394614 ITGA11 other 1 1 1 -1.07965468495969 -0.810752415014248 1.41884953569165e-07 162.776960394697 31.9159202302796 5.10018070042253 6.37031390516758e-07 14.6079359210888 55.4256229180056 0.263559255665908 0.792319111899365 KNL1 other 0.00134563689964996 1 0.00715641064106526 5.10018070042253 0.263559255665908 9.44837039055254e-11 148.56902154613 28.1837367414772 5.27144512130945 2.76062569932136e-07 -75.2012266129454 49.8594076361611 -1.50826554462321 0.132647197898325 HAUS2 other 1.07645283859565e-06 1 0.00317913655533848 5.27144512130945 -1.50826554462321 1.10050654658427e-18 436.24863080056 61.5236392946916 7.09074813846716 1.15175691468891e-11 -239.252951605144 107.587554821077 -2.2237976502304 0.0269834285366155 RTF1 essential 1.57669572929128e-14 1 1.58193812232522e-07 7.09074813846716 -2.2237976502304 5.29041898003696e-05 193.370606433639 62.7466444963926 3.08176808474206 0.00227218260247391 -214.238321617156 116.61099423901 -1.83720517104969 0.0672867663902665 PARP6 other 0.404188010074824 1 1 3.08176808474206 -1.83720517104969 1.59798567061663e-06 4994.78010704724 1302.14771156233 3.83580147067528 0.000155857999914665 -4605.24261305156 2469.02667677146 -1.86520569274426 0.063237205268789 RPLP1 essential 0.014009540374296 1 1 3.83580147067528 -1.86520569274426 0.042779227104866 52.9309927360775 27.572581738486 1.91969664785492 0.0559499231351263 -39.7847457627119 52.2808889155159 -0.760980667849828 0.447332698745487 PAQR5 other 1 1 1 1.91969664785492 -0.760980667849828 0.000202934397763935 50.7057904933077 12.1088227908906 4.18750785018121 3.82148969534148e-05 35.2122591591345 22.7766118956333 1.54598319190245 0.123279892588378 LRRC49 other 1 1 0.373130253853142 4.18750785018121 1.54598319190245 3.98092882886933e-16 316.619997531382 43.7862880450607 7.23103080136746 4.86899506387953e-12 -88.9210609856723 78.346993836393 -1.13496455487955 0.257389326950713 TUBGCP4 essential 5.4168498574425e-12 1 6.74940095754981e-08 7.23103080136746 -1.13496455487955 5.20353690177365e-07 103.565516891283 44.7998892733255 2.31173600138666 0.0215423587366857 -243.686096000247 77.8661968850778 -3.12954922352124 0.00194199851491555 RMDN3 other 0.00474510530072739 1 1 2.31173600138666 -3.12954922352124 0.000480937725592604 29.1449473080648 7.84894527846986 3.71323104876412 0.000248240809995792 9.69393334256009 13.7255994625121 0.706266663910495 0.480626833957026 ITPKA other 1 1 1 3.71323104876412 0.706266663910495 0.388724995310803 47.2939958592128 61.7883773835561 0.765418964890949 0.444693139514121 -88.7506569517439 117.990880555693 -0.752182342684124 0.452599068547302 UACA other 1 1 1 0.765418964890949 -0.752182342684124 0.699217957781886 25.4066981020567 39.1069038775689 0.649672962646106 0.51645377626769 -18.2211327716052 78.6251125210981 -0.23174698499434 0.816909429124493 SMAD6 other 1 1 1 0.649672962646106 -0.23174698499434 0.458006321092134 -35.3432037103104 38.0880456605969 -0.927934292697878 0.354261328211658 -78.8735080919795 66.0680535852969 -1.19382218503153 0.233583860399054 PLCB2 other 1 1 1 -0.927934292697878 -1.19382218503153 0.000117285745541314 22.574271272671 30.1515119258021 0.748694504216654 0.454688278930122 -179.240839564361 53.4491563178762 -3.35348304654929 0.000911406697564353 TMEM62 other 0.861463801000949 1 1 0.748694504216654 -3.35348304654929 5.67627558556316e-08 442.488275446649 131.586943609211 3.36270653690961 0.000883104680395691 -813.776103657636 256.679062311905 -3.17040313427969 0.00169702759523287 ADAM10 other 0.000551847512428451 1 1 3.36270653690961 -3.17040313427969 0.00717212727522254 -5.59816623411542 149.879970076187 -0.0373509964758451 0.970232542293246 -753.448044735071 268.669554174969 -2.80436704876651 0.00540490959043284 DUOX1 other 1 1 1 -0.0373509964758451 -2.80436704876651 0.492186011520573 -80.7655722749209 98.1844372762674 -0.822590366818175 0.411469552054233 83.6104335765798 184.497022255441 0.453180395837602 0.650784176215957 STRA6 other 1 1 1 -0.822590366818175 0.453180395837602 0.217780586857808 3.3485714717963 2.06877456091173 1.61862560332362 0.106691043658445 0.368271696457606 4.03218005831752 0.0913331476102961 0.927295353550165 CYP19A1 other 1 1 1 1.61862560332362 0.0913331476102961 0.0180437169498633 226.234755181735 91.1469054715758 2.4820892603127 0.0136698928601322 -29.183275758487 172.587837551728 -0.169092307850141 0.865850645415044 SEMA6D other 1 1 1 2.4820892603127 -0.169092307850141 0.107393954819384 6.18223158709506 6.3571406872397 0.972486199574642 0.331679138896546 -16.0531235554027 12.4053500349474 -1.29404841541585 0.196754477868848 BCL2L10 other 1 1 1 0.972486199574642 -1.29404841541585 3.59463922380331e-07 515.201965899498 113.756187716369 4.5290016854649 8.88902478716695e-06 -256.418646875223 219.994982279733 -1.16556588799455 0.244814848868533 RSL24D1 essential 0.00332144664279426 1 0.0916280675061169 4.5290016854649 -1.16556588799455 0.013749446382521 4.02783149110618 16.3373792003014 0.246540858342314 0.805452313354034 -68.2662833823262 28.3756748992422 -2.4058029852939 0.0168146270129879 SPTBN5 other 1 1 1 0.246540858342314 -2.4058029852939 0.0176815808480853 -16.142313825134 36.6369654010273 -0.440601825190505 0.659852532189 -169.077075229594 63.6783083052565 -2.6551753608008 0.00839592746643548 GCHFR other 1 1 1 -0.440601825190505 -2.6551753608008 2.80282692465797e-06 164.330586064921 54.9093211003605 2.99276302769371 0.00301766113688871 -178.316344326309 88.4332881887222 -2.01639391657325 0.0447379878024795 BCAR3 other 0.0240286352250928 1 1 2.99276302769371 -2.01639391657325 0.441697872853697 11.3705134614459 38.5652317638152 0.294838457890834 0.768342195005852 -52.7667522888956 59.9039191849825 -0.880856428207185 0.379173188110789 TTLL7 other 1 1 1 0.294838457890834 -0.880856428207185 1.00977245285014e-09 239.082158751539 84.0253969941148 2.84535589600707 0.00477231464089805 -493.72152530119 135.325696960831 -3.64839447635798 0.000316053700386353 FNBP1L other 1.09045327183287e-05 1 1 2.84535589600707 -3.64839447635798 1.16358459875307e-14 111.464417881759 22.5133177196996 4.95104361203171 1.29700213611627e-06 -141.680015301727 40.7455591649026 -3.47718912699981 0.000589711963888187 KYAT3 other 1.52383039052702e-10 1 0.0142696175015512 4.95104361203171 -3.47718912699981 7.74628352650455e-19 112.982629720277 21.951625154682 5.14689135424576 5.08178198426165e-07 -186.196460861098 39.7289840903021 -4.68666554467847 4.3947863307505e-06 GTF2B essential 1.11352825693503e-14 0.0681060037676404 0.00574139728581881 5.14689135424576 -4.68666554467847 0.000852811718038361 87.6970552114403 35.0376783833668 2.50293567547192 0.0129014307865345 -74.5499585178225 61.9423279116427 -1.20353821096559 0.229810697904178 BRDT other 1 1 1 2.50293567547192 -1.20353821096559 2.76968367366648e-23 522.262549422442 55.7523975181371 9.36753525716168 3.01273670027533e-18 -35.0439838203827 95.8468915257412 -0.365624625509853 0.714930420244903 RABGGTB essential 4.19163927172685e-19 1 4.55977699586671e-14 9.36753525716168 -0.365624625509853 0.524114579414433 -85.9610033453807 82.9772273311727 -1.03595897465095 0.30114821023416 -17.0506979216242 141.312418809112 -0.120659585798023 0.90405041169954 IFI44L other 1 1 1 -1.03595897465095 -0.120659585798023 0.212077663675092 16.9700582874205 16.4073798728246 1.03429422729024 0.301920717074797 -19.6090486814673 27.9370264637249 -0.701901782816037 0.483342787497143 GIPC2 other 1 1 1 1.03429422729024 -0.701901782816037 0.0495240165194349 158.489714015192 91.862324311113 1.72529614511419 0.0856057630903262 -84.3078263863485 148.583771563671 -0.567409384612512 0.570902364770095 ARHGAP29 other 1 1 1 1.72529614511419 -0.567409384612512 0.0326675824803859 -71.7194950475233 71.739912254168 -0.999715399615038 0.318343360239369 -318.322006017987 122.174973204744 -2.60546000271705 0.0096840576013026 IFI44 other 1 1 1 -0.999715399615038 -2.60546000271705 5.27857860704734e-08 101.256639659598 41.2525691543178 2.4545535401884 0.0147350471624753 -236.614944887357 70.9194706757815 -3.33638904284941 0.000967418494388258 SLC44A5 other 0.000514344699470693 1 1 2.4545535401884 -3.33638904284941 0.0748283211221326 636.254189766447 868.388297109366 0.732683975457026 0.46437980173857 -2190.79730582727 1490.6424610613 -1.46970005420848 0.142794477380673 CLCA2 other 1 1 1 0.732683975457026 -1.46970005420848 3.70021492874077e-13 72.9071603082129 38.8023889236351 1.87893483701989 0.0613266178604439 -284.24563052058 55.764641028968 -5.09723769893762 6.47545406182862e-07 DBT other 4.62970891884045e-09 0.0101625776046338 1 1.87893483701989 -5.09723769893762 7.712843251822e-18 119.159305474447 31.9828007438049 3.72573078977544 0.000236991437515621 -222.158823655543 45.9639071730691 -4.83333200589416 2.2514730418839e-06 RTCA other 1.08959336618489e-13 0.035062189681258 1 3.72573078977544 -4.83333200589416 0.119745485963901 55.9193005189922 29.17115137668 1.91693840935244 0.0562895002871514 -82.5336012696775 109.110926898843 -0.756419211305892 0.450050142637826 IFT172 other 1 1 1 1.91693840935244 -0.756419211305892 3.85752333598234e-08 761.877277116456 127.685883539716 5.96680898463985 7.48460521532976e-09 526.819626238242 476.500718698697 1.10560090586424 0.269872666759182 SELENOI other 0.000379078818226985 1 9.34003884821001e-05 5.96680898463985 1.10560090586424 0.0844997322796228 80.0934704070588 35.8783686967981 2.23236098285055 0.0264023527220904 19.6029251644052 133.891609595539 0.146408914073271 0.883706644132874 CGREF1 other 1 1 1 2.23236098285055 0.146408914073271 9.90102569307179e-09 378.25209954542 60.2042413811885 6.28281481283824 1.31386870663807e-09 65.7576084444103 224.468313134805 0.292948289787875 0.769785039650396 HADHB other 0.000100960758992253 1 1.69173734666718e-05 6.28281481283824 0.292948289787875 0.00485921002323942 46.4314684092231 14.7948850230131 3.13834601194941 0.00188523065688619 -48.864008157829 55.2118460639191 -0.885027609858559 0.376920570743734 KHK other 1 1 1 3.13834601194941 -0.885027609858559 1.50885968869112e-05 462.657278354599 96.7154596970949 4.78369517969107 2.82507974778482e-06 -9.08591923902897 336.502954695022 -0.0270010087943022 0.978478728673038 ADCY3 other 0.121780065474261 1 0.0303159307734789 4.78369517969107 -0.0270010087943022 1.00329670391086e-11 219.367478765558 29.452983863059 7.44805618967173 1.24770559892978e-12 60.1015268230446 118.47283724618 0.507302164952437 0.612352372338417 PPM1B other 1.18990989083828e-07 1 1.75414930153538e-08 7.44805618967173 0.507302164952437 4.74927667131959e-17 359.323534892342 38.8735053737166 9.24340451003654 7.98436455421602e-18 358.483625785774 191.408464159389 1.87287237980896 0.062182784832547 PNPT1 essential 6.60624384980555e-13 1 1.20420186206686e-13 9.24340451003654 1.87287237980896 1.67333883113514e-06 67.1324966806685 12.7042617138961 5.28425013530997 2.59114613743509e-07 25.7759068040414 50.9603376303944 0.505803297281684 0.613404402748363 DYNC2LI1 other 0.0146417147724325 1 0.00299095998644132 5.28425013530997 0.505803297281684 2.32239662816943e-05 51.3106751582514 11.11322271443 4.61708331388221 5.99819392781324e-06 -19.8977388499664 42.3622458875515 -0.469704531312716 0.638941081921724 THUMPD2 other 0.184096380714991 1 0.0626871247395762 4.61708331388221 -0.469704531312716 0.775669688317564 -194.274949796852 277.241823320247 -0.700741855865093 0.484063130091623 -181.998664362771 1023.99337004524 -0.177734221418572 0.859063997543808 CYP1B1 other 1 1 1 -0.700741855865093 -0.177734221418572 1.54011878578376e-12 679.894192651295 90.0926298776595 7.54661278702322 7.18871867845774e-13 1142.24005592964 530.60347544968 2.15271876039185 0.0322436283541093 RAB1A other 1.88587545319221e-08 1 1.01583783645286e-08 7.54661278702322 2.15271876039185 6.03539753623737e-13 1172.17370919295 155.896288465948 7.51893275155803 8.5604757364203e-13 2552.44022519042 918.156264081374 2.77996276346724 0.00582608097315653 ACTR2 essential 7.50079205803581e-09 1 1.20745510262208e-08 7.51893275155803 2.77996276346724 0.0158792123810801 265.271948722217 91.5383510839432 2.89793234836572 0.00406100395289272 -2.68128860401234 341.604638436209 -0.00784909893579518 0.993743122036587 PREB essential 1 1 1 2.89793234836572 -0.00784909893579518 0.0517158337828904 218.2958048682 90.0404146099687 2.42442025410256 0.0159824027744694 120.781914876011 336.784550242456 0.358632588071687 0.720147145794784 SLC5A6 other 1 1 1 2.42442025410256 0.358632588071687 1.122820115294e-07 281.314684303385 48.2798051059745 5.82675683312925 1.58832067553017e-08 154.514337867847 194.202581279768 0.795634830647558 0.426935559156718 PREPL other 0.00107229321010577 1 0.000195347559883456 5.82675683312925 0.795634830647558 1.41094418193158e-06 72.0145435438619 13.5417875238956 5.31794959984319 2.18645057648999e-07 25.8122001227629 54.4710171573836 0.473870352892135 0.635971111468951 SLC3A1 other 0.0124177197451799 1 0.00253344028297895 5.31794959984319 0.473870352892135 0.0290999421229396 -258.595978523266 154.958423375915 -1.66880878683139 0.0963016582452246 1172.10703321402 578.276925060971 2.026895735275 0.0436448556191164 EMILIN1 other 1 1 1 -1.66880878683139 2.026895735275 6.9191497927336e-20 430.34344760048 42.2029364138276 10.1970024877103 7.41536020983982e-21 49.585259150613 209.966584877061 0.236157859021454 0.813489890759509 FBXO11 other 1.01005748674325e-15 1 1.13951840344609e-16 10.1970024877103 0.236157859021454 0.339998785654638 3.14629504890593 13.2978314540358 0.236602115147959 0.813143561448153 78.6739457497229 53.4901618797142 1.47081150972473 0.142497980178097 SIX3 other 1 1 1 0.236602115147959 1.47081150972473 4.98817729311175e-10 819.344543134608 120.494933096246 6.79982570287955 6.58835008300601e-11 -138.484641240021 450.69574618353 -0.30726857844278 0.758873211692842 ATRAID other 5.48250566285912e-06 1 8.86198969665138e-07 6.79982570287955 -0.30726857844278 3.03691128041906e-10 336.759698886081 48.9169406770107 6.88431643977168 4.00737009706773e-11 61.0220782964004 170.99816780114 0.356858082639605 0.721474738949714 CENPO other 3.37461581480166e-06 1 5.41796437123557e-07 6.88431643977168 0.356858082639605 7.04377360993458e-14 1140.2957444347 139.301523328497 8.18580958189295 1.04221068930792e-14 1070.49838351507 560.331909940751 1.91047192659126 0.0571200285739884 LRPPRC essential 9.02096086224321e-10 1 1.51829253218377e-10 8.18580958189295 1.91047192659126 0.759333485530066 5.25957388357098 14.753874691424 0.356487634168957 0.72175077135101 36.1439888919782 55.1849641498059 0.654960811315582 0.513044451211636 TRIM54 other 1 1 1 0.356487634168957 0.654960811315582 1.39930052676833e-06 163.531455384472 30.7190621322884 5.32345208588209 2.13276051482644e-07 42.730011963767 113.560367986197 0.376275744095517 0.707005239588548 DTNB other 0.0123180425371416 1 0.00247272254088978 5.32345208588209 0.376275744095517 1.86455490523524e-14 459.133698254654 104.861442945576 4.37847969050884 1.70423704026126e-05 -526.640190721999 156.319851752727 -3.36899110904391 0.000863174274545624 ACTR1A essential 2.42615884269209e-10 1 0.171633712324712 4.37847969050884 -3.36899110904391 0.281340604910199 -4.89459111882862 3.80373810116409 -1.28678447060555 0.199267502858031 1.63418566164483 6.47190587909904 0.252504546909808 0.800842511100695 CYP2C9 other 1 1 1 -1.28678447060555 0.252504546909808 1.89348678549328e-08 70.1257768084839 18.2165062328844 3.84957334364659 0.000147434009315252 -46.5799787038044 27.1558494122102 -1.71528343660871 0.0874279354412538 MFSD13A other 0.000189708441038572 1 1 3.84957334364659 -1.71528343660871 6.50317612280285e-14 1774.40972472941 269.357478542686 6.58756435622117 2.30389964156127e-10 -595.541029012065 458.389503481541 -1.29920302382327 0.194974426347481 MYOF other 8.33707178943325e-10 1 3.04276025660996e-06 6.58756435622117 -1.29920302382327 0.316342625367308 -85.5295006700672 137.266642934851 -0.62309020488438 0.53374542072246 -331.155809505662 218.64438096738 -1.51458641672144 0.131034076711675 LOXL4 other 1 1 1 -0.62309020488438 -1.51458641672144 1.11137304591423e-07 -4.35406459530444 11.8322156837065 -0.367983876536344 0.713175723408281 -81.7549109226884 17.0151167076548 -4.80483985666161 2.58167478852178e-06 STAMBPL1 other 0.00106158353345728 0.0401786047337645 1 -0.367983876536344 -4.80483985666161 0.428379659742086 -61.9805572783181 65.1951268987396 -0.950693099724855 0.342613571185442 -120.602730598998 93.5753141459341 -1.28883062482605 0.198564251674925 CH25H other 1 1 1 -0.950693099724855 -1.28883062482605 1.31960226501787e-20 215.394528802552 49.4285667915639 4.35769318804757 1.88645280395353e-05 -327.398128347033 71.2956427158067 -4.59211974078251 6.80775052993991e-06 ATAD1 other 1.94351021591832e-16 0.105077629429623 0.189418726044974 4.35769318804757 -4.59211974078251 0.598950427752928 -27.8358152686146 56.8713410734667 -0.48945241563156 0.624915914538878 -79.8962227216704 79.1378458240673 -1.00958298636646 0.31359237503022 BTBD16 other 1 1 1 -0.48945241563156 -1.00958298636646 3.33368181508769e-05 290.341390639237 86.7562000985645 3.34663563306574 0.000933294874012035 -55.0681420926334 120.636203383125 -0.45648106081177 0.648408378360129 KIF11 essential 0.259960507940538 1 1 3.34663563306574 -0.45648106081177 7.33327616754497e-07 25.2318742985409 6.03082287862681 4.18381948970222 3.86781699282993e-05 -4.83507726841057 8.37869858874239 -0.577067812763544 0.564369200251292 CUZD1 other 0.00659774856794021 1 0.377518290722743 4.18381948970222 -0.577067812763544 0.000118623072414883 236.383600377003 184.326588901154 1.28241726701601 0.200788145508389 -695.774262306968 256.494904083446 -2.71262411545069 0.00710095567076563 TACC2 other 0.870574728452824 1 1 1.28241726701601 -2.71262411545069 2.81315476181531e-05 301.723223874678 138.70208697983 2.17533297763974 0.0304696208251813 -433.740693534918 196.759885371938 -2.20441627476562 0.0283356098867726 DUSP5 other 0.221057701183447 1 1 2.17533297763974 -2.20441627476562 0.00127932046845661 0.0559400551805858 27.3192424505724 0.00204764298577443 0.998367719365731 -126.171367636558 41.4315872043517 -3.04529408960964 0.00255256994468724 CALHM2 other 1 1 1 0.00204764298577443 -3.04529408960964 2.923716212224e-05 119.762981273214 45.074046097693 2.65702752785142 0.00834938460394016 -107.84067607967 67.1524133312273 -1.60590916588134 0.109454168747665 ARL3 other 0.229307062524729 1 1 2.65702752785142 -1.60590916588134 3.30575920225006e-16 580.443099540374 68.017762031529 8.53369887811533 1.00994048061636e-15 156.490299738208 115.377462299422 1.35633334812038 0.176117901181847 CEP55 essential 4.50674152042751e-12 1 1.49067214938974e-11 8.53369887811533 1.35633334812038 1.69038849478099e-10 137.214954132698 33.1417872496995 4.14024002685437 4.63753105815617e-05 -90.785249803391 47.400782180849 -1.91526902355781 0.0565106534902303 KIF20B other 1.90185609547809e-06 1 0.44900575705068 4.14024002685437 -1.91526902355781 0.358727454894644 -30.8060669765986 41.5862951383803 -0.740774499726172 0.459469181068673 -93.5346043540281 65.213043020557 -1.43429289635424 0.152637356923 ENTPD1 other 1 1 1 -0.740774499726172 -1.43429289635424 1.01862027442474e-06 81.6607073521301 21.0850912305493 3.87291221362207 0.000134776602852757 -53.6797957779582 35.8823692303863 -1.49599362944241 0.135814680765531 EXOC6 other 0.0090596087207336 1 1 3.87291221362207 -1.49599362944241 3.54023007493846e-25 711.829867587678 60.7526120815848 11.7168602830074 6.08495038596518e-26 414.338190527645 103.178668865912 4.01573498749153 7.6715994379017e-05 PLCE1 other 5.42858879691063e-21 1 9.52903230442148e-22 11.7168602830074 4.01573498749153 0.459067408227876 -3.47527025460205 22.7675459653255 -0.152641407198422 0.878794237226951 -45.1327729315719 38.5463192542444 -1.17087114424297 0.242675320606284 RBP4 other 1 1 1 -0.152641407198422 -1.17087114424297 9.52619368350352e-19 92.0659178973728 9.72497415262115 9.46695759315294 1.56419949232942e-18 -73.9389696177486 50.2738578773473 -1.47072400527003 0.142538876491263 DBR1 essential 1.36624669808807e-14 1 2.37304704981296e-14 9.46695759315294 -1.47072400527003 3.01328920658436e-12 211.977648187718 33.0315469332277 6.41743024074 6.10200978571006e-10 -490.24268166057 162.228575353132 -3.0219255799629 0.0027501560299914 DNAJC13 other 3.64457329536379e-08 1 7.94298613805879e-06 6.41743024074 -3.0219255799629 7.2820178975688e-05 200.657849182017 52.7695423926757 3.80253153777335 0.000177395684985048 -725.516626812842 350.489311636684 -2.07001070424912 0.0394092896974468 GPR87 other 0.548044666971028 1 1 3.80253153777335 -2.07001070424912 1.56355995729731e-14 918.521841457204 175.327564255097 5.23889010470012 3.25715277899498e-07 -591.644851879181 277.695872130705 -2.13054968134603 0.0340301089189576 ANXA7 other 2.03937910388891e-10 1 0.00373334851528405 5.23889010470012 -2.13054968134603 1.59039002010094e-20 283.909026131414 40.8994028149219 6.94164233683703 2.87935645546616e-11 -111.684407983263 63.9871252410836 -1.74541999757718 0.0820493639354052 FAM149B1 other 2.33946371956848e-16 1 3.90872638829531e-07 6.94164233683703 -1.74541999757718 2.59735518722976e-20 235.684867787314 38.4149864667084 6.13523235239366 2.99001929320698e-09 -160.369368919822 60.0465412872062 -2.67075114539514 0.00802410882361533 ASCC1 other 3.81161873725967e-16 1 3.7949324869383e-05 6.13523235239366 -2.67075114539514 0.0533267069983437 -8.71645458721354 15.4568556200625 -0.563921589323761 0.573277329662898 -51.9024108328028 23.217293679383 -2.2355064956986 0.0262048140506928 ZNF365 other 1 1 1 -0.563921589323761 -2.2355064956986 0.908606857180441 10.6308768973625 26.8415224850305 0.396060875581529 0.692370622531702 4.34318716112469 42.1392576080939 0.103067481670358 0.917985360867719 ADAMTS14 other 1 1 1 0.396060875581529 0.103067481670358 1.450781976585e-12 4754.74928104573 951.921662161088 4.99489555711057 1.05838412972961e-06 -2537.86069716778 1442.25690210009 -1.75964538181261 0.0796004224510219 RPS24 essential 1.77749807771195e-08 1 0.0117163123161068 4.99489555711057 -1.75964538181261 6.29728350172062e-05 46.0640878616798 16.9309871369324 2.72069711524367 0.00693598434867467 -30.0615748500352 26.1588749862775 -1.1491921906353 0.251489971768529 TET1 og 0.477963817780595 1 1 2.72069711524367 -1.1491921906353 8.11526699665935e-09 119.832502646437 24.8849261407186 4.8154654737093 2.44515581398247e-06 -11.2246521039165 38.4479455741734 -0.291944132158168 0.770552702536203 DNA2 other 8.31490256477717e-05 1 0.026358779674731 4.8154654737093 -0.291944132158168 0.669252939282256 2.91154446755533 39.5404001568115 0.0736346738022013 0.941356629919683 -75.8574279977929 90.948799789796 -0.834067389268657 0.404994212048315 AOX1 other 1 1 1 0.0736346738022013 -0.834067389268657 1.41824624199474e-13 636.744411052163 123.314266838122 5.16359077808924 4.67494542586273e-07 -460.186806615446 185.487253451989 -2.48096188849204 0.01370546036144 ATIC other 1.79932900721873e-09 1 0.00529811565113023 5.16359077808924 -2.48096188849204 5.10448000500151e-13 91.8971602931703 24.9522215893251 3.68292498382128 0.000277923171677227 -146.773157245404 37.5327135197183 -3.91053945961822 0.000116268574770835 SMARCAL1 other 6.35609850222788e-09 1 1 3.68292498382128 -3.91053945961822 1.28710531791296e-09 114.802968505627 23.2863066102606 4.93006342427191 1.42883231449419e-06 -37.7260831719416 35.0268721286582 -1.07706114988997 0.282403780285546 BARD1 other 1.38299466409748e-05 1 0.0156728616576868 4.93006342427191 -1.07706114988997 0.0230790111321964 -24.7224638411325 9.00394474565734 -2.7457369563553 0.00644927000690891 -24.3586169896978 22.7285897927221 -1.07171704060133 0.284818534205228 STAT4 other 1 1 1 -2.7457369563553 -1.07171704060133 4.96369585440479e-06 31.3478616525672 8.17359141114939 3.83526164640508 0.000156305936807474 -37.4367201048867 18.7555743718974 -1.99603165238065 0.0469385251289879 CARF other 0.0417099362645634 1 1 3.83526164640508 -1.99603165238065 2.6201494828028e-08 185.335342320853 32.6474033125652 5.676878511484 3.55964628231036e-08 -46.7234872058471 83.1821938520362 -0.561700588096515 0.574789457525758 ASNSD1 other 0.000260338052611287 1 0.000430290042605676 5.676878511484 -0.561700588096515 1.14015831977434e-13 306.159433382266 41.7486646813501 7.33339462996126 2.580022286339e-12 -75.6404436581722 111.583934551377 -0.677879337758472 0.498424429137332 METTL5 other 1.45085146191285e-09 1 3.60171111172924e-08 7.33339462996126 -0.677879337758472 4.84294652243318e-16 691.385001442892 87.4799993825732 7.90334940926648 6.79225629002724e-14 -254.435304450383 233.81256862139 -1.08820199850927 0.277469213212113 SSB other 6.57575278815977e-12 1 9.76658531943017e-10 7.90334940926648 -1.08820199850927 1.05400273151631e-06 343.729072035271 70.0199896047118 4.90901346852157 1.59547220530964e-06 -125.737502302918 175.770021904469 -0.715352373178039 0.475016403243962 NAB1 other 0.00936692227498549 1 0.0174512749816768 4.90901346852157 -0.715352373178039 0.951023701436897 0.0356786857232712 1.25830054187297 0.0283546613356486 0.977400231237483 -0.83533767528312 2.85632749414959 -0.292451645336216 0.770165933124934 CDK15 other 1 1 1 0.0283546613356486 -0.292451645336216 1.11851692918224e-12 367.005577895966 53.2288382674604 6.89486357098125 3.73825922920365e-11 -130.844175638864 142.283712017992 -0.919600520559366 0.358593376905393 PPIG other 1.37577582289415e-08 1 5.05898621488131e-07 6.89486357098125 -0.919600520559366 1.48651142849522e-10 113.742079687079 18.4579476865706 6.16222787161944 2.56408347946856e-09 -44.1480287775528 49.3391439407883 -0.894787084886082 0.371689123030831 FASTKD1 other 1.67663624019975e-06 1 3.2620270025799e-05 6.16222787161944 -0.894787084886082 0.0616131663289864 4.30864683980022 5.28211454007936 0.815704924061621 0.41538792838407 -14.990645926077 9.25718003937761 -1.61935339512797 0.106538666953341 MDH1B other 1 1 1 0.815704924061621 -1.61935339512797 0.713775807685452 24.8412029102861 30.6135037652937 0.811445925978864 0.417819133370334 26.4211378459905 76.3513256620288 0.346046877600323 0.729574997220078 HECW2 other 1 1 1 0.811445925978864 0.346046877600323 0.000103198210985489 1075.49316879367 277.489903448242 3.8757920754197 0.000133710511505736 -8.18243669497046 480.44425310713 -0.0170309804770335 0.986424572481109 IDH1 other 0.763873157714592 1 1 3.8757920754197 -0.0170309804770335 4.54994515002258e-12 657.741050261919 92.2497347223578 7.13000478799759 9.19428538856185e-12 -38.8093303266728 268.544667484372 -0.144517225719745 0.885199868467393 OLA1 other 5.45765920745209e-08 1 1.26632892656662e-07 7.13000478799759 -0.144517225719745 3.55820798709295e-08 115.025356996073 21.8854089698301 5.25580112094958 2.99697102026246e-07 -74.574813959793 63.4548406613284 -1.17524231693866 0.240933125849148 CIR1 other 0.000350305576329301 1 0.00344262061097548 5.25580112094958 -1.17524231693866 9.16238329788783e-07 1081.53275045354 222.87609305739 4.85261894004506 2.05527303239954e-06 -379.051928950866 597.204137738035 -0.634710821640587 0.526150539069327 SSFA2 other 0.00817925957002447 1 0.0222853254903082 4.85261894004506 -0.634710821640587 0.0925309434624803 -8.86664677282544 6.10530912627726 -1.45228465740799 0.147583539869703 19.4233671747248 17.7018130358057 1.0972529839422 0.273508428442526 CHRNA1 other 1 1 1 -1.45228465740799 1.0972529839422 3.08625517963254e-16 610.454538264327 67.9657995748393 8.98178998971588 4.85519321428831e-17 247.902947445991 156.432236206941 1.58473057380606 0.114206806906619 FAM117B other 4.21150381812657e-12 1 7.26870976111102e-13 8.98178998971588 1.58473057380606 2.49242592005158e-23 389.838825769741 35.4355009989971 11.0013634569686 1.72293875685028e-23 76.6712291294346 81.3122580956951 0.942923378652226 0.346566165281186 WDR12 essential 3.7737820855501e-19 1 2.68054811790767e-19 11.0013634569686 0.942923378652226 6.10415708937673e-12 555.125602420385 84.8972580074795 6.53879307116701 3.15708311531518e-10 -308.450032870877 187.742796286029 -1.64293937755646 0.101576994308547 ABI2 other 7.29202605896944e-08 1 4.1499857550818e-06 6.53879307116701 -1.64293937755646 0.207649819296601 307.625134321783 301.277286425422 1.0210697858165 0.308138778115146 -797.427394301284 775.275070940463 -1.02857350144633 0.304604100307192 ITGAV other 1 1 1 1.0210697858165 -1.02857350144633 0.427288942444766 -43.0701920769073 370.904446170027 -0.116122070041629 0.907642762586942 -1210.63377626641 945.026017736086 -1.28105867303697 0.201280467919678 SLC40A1 other 1 1 1 -0.116122070041629 -1.28105867303697 4.8596306642059e-13 153.670546819018 21.2742680963149 7.22330592635695 5.14573142814962e-12 -132.142019522667 79.0378963283007 -1.67188178913299 0.0957018082750314 SLC35A5 other 6.05509980760055e-09 1 7.12786717427285e-08 7.22330592635695 -1.67188178913299 2.3858087895718e-12 171.634129622648 22.7231100019704 7.55328516245199 6.52707429223293e-13 -11.6062944422381 88.782071364016 -0.130727907830073 0.896087543816614 DIRC2 other 2.89851909845078e-08 1 9.23189387893426e-09 7.55328516245199 -0.130727907830073 1.62379337834237e-09 61.2349584047126 12.2497221344453 4.99888550390254 1.04946646420727e-06 -128.4986139938 45.3430188960378 -2.83392277625847 0.00495182297353852 SENP7 other 1.73469846608316e-05 1 0.0116228410910955 4.99888550390254 -2.83392277625847 3.33536773416051e-08 115.662873495335 19.2915281324501 5.99552677741374 6.45459132519123e-09 16.0174741960317 73.3643944968841 0.218327627534797 0.827338167409079 COX17 essential 0.000329067380652276 1 8.07727558434431e-05 5.99552677741374 0.218327627534797 8.48472092983911e-06 364.741097709469 82.3046838165117 4.43159588004268 1.3593779566624e-05 -453.837025705736 324.013245555579 -1.40067429937178 0.162455453990883 PARP9 other 0.0699141004618743 1 0.138085612837767 4.43159588004268 -1.40067429937178 1.47491779359382e-05 51.7391904242837 11.030876280239 4.69039712801156 4.335319161315e-06 19.1842169710297 21.389322749489 0.896906236616959 0.370567962082868 MNS1 other 0.119129110188573 1 0.0458503354500674 4.69039712801156 0.896906236616959 2.2315864194139e-22 290.796429293023 36.1006459290569 8.05515862138535 2.53557672622627e-14 -226.542841825395 68.8855174541742 -3.28868607216462 0.00113964048459929 USP8 essential 3.35184280195967e-18 1 3.67252933026613e-10 8.05515862138535 -3.28868607216462 0.0710873065871664 46.3972865846203 101.355378397061 0.457768372220549 0.647485667788323 -357.824577634509 193.700697948723 -1.84730659942812 0.0657925890784685 SECISBP2L other 1 1 1 0.457768372220549 -1.84730659942812 3.13721988623586e-10 392.589147167025 92.6379090077989 4.23788869342867 3.10331255537013e-05 -564.04429946939 180.88653303083 -3.11822162777178 0.00201698473652596 TMOD3 other 3.48325523968767e-06 1 0.305738352955065 4.23788869342867 -3.11822162777178 1.00209488575967e-08 247.507898076614 65.4384900348705 3.78229842932994 0.00019136902064543 -363.214316187979 124.951270394967 -2.90684772583641 0.00395385715365701 SPPL2A other 0.000102123489807768 1 1 3.78229842932994 -2.90684772583641 0.00104292576830968 358.710447011551 97.1056632452319 3.69402190380657 0.000267162178164595 155.653989104816 185.647885589721 0.838436638318678 0.402527160453546 GLCE other 1 1 1 3.69402190380657 0.838436638318678 0.0860379999089387 15.826946955463 16.6423665780884 0.95100338531787 0.342446920426024 -39.1918677442855 29.8325200270494 -1.3137297053266 0.190044152913527 SHF other 1 1 1 0.95100338531787 -1.3137297053266 0.0400956411026372 15.3734447180775 25.6578076436941 0.599172186944653 0.549554959315645 -103.958003681762 50.903061871158 -2.04227407665364 0.0420851046994826 APH1B other 1 1 1 0.599172186944653 -2.04227407665364 4.29938351436585e-25 368.749189138704 38.3932868014557 9.60452255743633 5.58228498614269e-19 -179.04486482815 77.3132937017609 -2.31583543082284 0.0213166690004489 INTS14 other 6.58794535906279e-21 1 8.49400483491471e-15 9.60452255743633 -2.31583543082284 0.246983775580946 -63.6876604230395 45.5779936294201 -1.39733356717856 0.163456243688404 27.4698509331952 91.503674269939 0.300204895075123 0.76425102542372 CILP other 1 1 1 -1.39733356717856 0.300204895075123 1.2292235052265e-10 94.8299628798039 15.5441022804653 6.10070373758279 3.63220856647467e-09 -26.2174654122484 31.2067811377332 -0.840120783253352 0.401581239533201 PARP16 other 1.39209561966901e-06 1 4.5958334991604e-05 6.10070373758279 -0.840120783253352 0.000118696067875183 27.0700224674165 12.1508265679854 2.22783382809032 0.0267249891982139 -57.7773814285042 22.8001805436318 -2.53407561040747 0.0118465863302595 PPCDC other 0.870991746068096 1 1 2.22783382809032 -2.53407561040747 0.779982168648876 -4.97957331730774 23.8826481475571 -0.208501724203356 0.834995022842183 -31.3180088141026 44.6869155170155 -0.700831741277324 0.484013793110152 HCN4 other 1 1 1 -0.208501724203356 -0.700831741277324 0.547886222979855 30.5466646149112 31.9890598484117 0.954909733504652 0.340480675090844 -6.39816181356555 60.1102012753463 -0.106440532186168 0.915312170351299 SEMA7A other 1 1 1 0.954909733504652 -0.106440532186168 1.60661741003999e-12 230.932698754658 36.6570555457564 6.29981582853541 1.2110710425244e-09 -108.067838831939 68.8817676248892 -1.56888887376476 0.117849356073776 UBL7 other 1.96569640118393e-08 1 1.56107057381395e-05 6.29981582853541 -1.56888887376476 3.09372017092798e-07 118.463856107711 49.025399209122 2.41637718445482 0.0163369813147615 -188.142959015122 74.7236241461997 -2.51785109682332 0.0123841147652348 ARHGAP24 other 0.00287190043467245 1 1 2.41637718445482 -2.51785109682332 3.57456180935047e-07 178.277432497755 53.9312604156884 3.30564186936552 0.00107491154913715 -124.752468752159 83.5477362162225 -1.49318789954162 0.136547046477566 FAM13A other 0.00330396748038264 1 1 3.30564186936552 -1.49318789954162 2.7372389207438e-05 -35.7620675367719 48.9697625584527 -0.730288767360973 0.465842209104271 -308.972267736407 75.8616203899158 -4.07284033940142 6.09643174453125e-05 HERC6 other 0.215365303048617 0.917147191647282 1 -0.730288767360973 -4.07284033940142 0.0098657822689742 36.2493957599613 35.911222013033 1.00941693788102 0.313671823339471 -91.3913152657714 55.6319522447932 -1.6427846152806 0.101582994065964 HERC5 other 1 1 1 1.00941693788102 -1.6427846152806 0.686807171523671 7.93243780724394 19.6179797246546 0.404345295416682 0.68628252686603 23.3106275645391 27.4299629228812 0.849823517081538 0.396184585746036 PCDH10 other 1 1 1 0.404345295416682 0.849823517081538 5.66729737317358e-10 52.6439153842635 12.3759525811533 4.25372633250325 2.9045630396528e-05 -33.8309830656682 19.2042032312512 -1.76164471174803 0.0792652784197765 ZGRF1 other 6.20569062362507e-06 1 0.287232238991266 4.25372633250325 -1.76164471174803 7.37378976079004e-15 112.838022479069 26.9729678552989 4.18337437260919 3.88733916692357e-05 -149.022989658661 41.8747915867299 -3.55877567414297 0.000440040024052961 AP1AR other 9.70759422008008e-11 1 0.379251154882403 4.18337437260919 -3.55877567414297 4.89573017622938e-10 144.851727108953 49.2029024108948 2.94396712411988 0.00352123801314509 -230.352610462737 74.6212879052189 -3.08695570566033 0.00223184250867363 COPS4 essential 5.38236575574658e-06 1 1 2.94396712411988 -3.08695570566033 1.85126513410792e-11 1264.30406047463 260.919073223305 4.84557930110611 2.13518362426441e-06 -580.540306271625 396.080047708523 -1.46571459388141 0.143893954920051 HNRNPD other 2.17377890349293e-07 1 0.0231090923654137 4.84557930110611 -1.46571459388141 5.42667523783809e-05 52.2977116567951 22.5211872066645 2.32215607360695 0.0209713251994373 -56.9496956554484 34.1875846524795 -1.66580050139102 0.0969172114009406 PRKG2 other 0.414218120904182 1 1 2.32215607360695 -1.66580050139102 0.0015953332520696 -60.5438026899279 67.6965639369154 -0.894340852311899 0.371939032408842 -343.271313532479 102.764653969504 -3.34036363937301 0.000955130583972077 RASGEF1B other 1 1 1 -0.894340852311899 -3.34036363937301 1.1859675840102e-10 766.245742720317 199.637085371066 3.83819339626249 0.000154548090520511 -720.130277852844 303.052840565968 -2.37625318577434 0.0181898408164332 SEC31A other 1.34429425647556e-06 1 1 3.83819339626249 -2.37625318577434 0.0106194512853058 62.7717465629791 21.9101729155021 2.86495897613689 0.0044997199290286 87.0548585480632 34.1326828739984 2.55048391213279 0.0113118934911913 FGF5 other 1 1 1 2.86495897613689 2.55048391213279 9.70034872901854e-06 295.43851149968 65.6162965830361 4.50251731482299 1.00125990819954e-05 118.06207981078 99.5126294705665 1.18640297657595 0.236509975970377 GPAT3 other 0.0796010616703262 1 0.10280072947302 4.50251731482299 1.18640297657595 3.17132783634853e-05 56.8860943831454 24.8904638334744 2.28545738495403 0.0230613575058779 -73.4771477048154 37.5472260623769 -1.95692612771842 0.0513865802530764 FGF2 other 0.247839270410637 1 1 2.28545738495403 -1.95692612771842 1.62472562236372e-17 85.9442204067441 12.4672145699425 6.89361845218809 3.86485253373566e-11 -23.0999255823049 18.6445969902308 -1.23896084181431 0.216439960315988 BBS7 other 2.28192713660985e-13 1 5.2283725076376e-07 6.89361845218809 -1.23896084181431 6.71752349100027e-16 220.19046086346 71.4753357435168 3.08064954956763 0.00227880292495981 -547.959003696832 108.818421331014 -5.03553531648838 8.72339794689049e-07 KIAA1109 other 9.08289291456302e-12 0.0136704369225721 1 3.08064954956763 -5.03553531648838 0.00411261779021523 -0.86739072202624 28.319037507259 -0.0306292444368528 0.97558793188496 -109.198879824668 41.5980520648749 -2.62509599378272 0.00915810138862521 BMPR1B ts 1 1 1 -0.0306292444368528 -2.62509599378272 1.57057793633569e-12 153.240293508309 45.7473550190788 3.34970827153614 0.000923852461545379 -221.083966302667 67.748990461186 -3.26328060090176 0.00124259902740486 RAP1GDS1 og 1.92238739407488e-08 1 1 3.34970827153614 -3.26328060090176 2.24755141089413e-10 170.819951852244 30.779527417991 5.54979124703511 6.80709105580351e-08 12.6528232599256 42.8169562717367 0.295509638275659 0.767830880189322 LARP1B other 2.51478527364944e-06 1 0.000811269112030662 5.54979124703511 0.295509638275659 0.426280793855415 -13.0656722602031 51.30998884129 -0.254641884655585 0.799192119539663 -92.5165263574216 79.486987322892 -1.16392040349449 0.245476203007258 MMRN1 other 1 1 1 -0.254641884655585 -1.16392040349449 0.424848686053851 20.1255570267707 87.560134470889 0.229848402453765 0.818383605796276 -116.875851083136 128.657465999011 -0.908426496477357 0.364463057175497 PDE5A other 1 1 1 0.229848402453765 -0.908426496477357 0.000425022418881948 37.1486155944532 11.6326350223647 3.19348243308863 0.00157287404527422 -1.05888042736985 17.0875810164702 -0.0619678365445191 0.950634462811886 PRDM5 other 1 1 1 3.19348243308863 -0.0619678365445191 3.00628163389378e-05 22.6389653808273 18.3110585215635 1.23635481554314 0.217401132300856 -116.781374835298 36.0906972853926 -3.23577496748905 0.00136434089981844 NAAA other 0.235391851933883 1 1 1.23635481554314 -3.23577496748905 4.34722636839078e-24 304.554314086019 43.690709827877 6.97068816885409 2.41775969637121e-11 -245.760659743548 71.4471790938691 -3.43975315555371 0.000674351878113547 NUP54 essential 6.62212992696967e-20 1 3.29032917079158e-07 6.97068816885409 -3.43975315555371 0.860981608802911 -98.8317792855288 229.327285940054 -0.430963890233993 0.666838482714814 -230.289317390372 451.999082761736 -0.509490674147596 0.610824492750912 CXCL9 other 1 1 1 -0.430963890233993 -0.509490674147596 2.10276192381265e-08 187.038580795711 68.8187613882625 2.71784288212446 0.00699446602039022 -303.456116867186 108.308569686251 -2.80177383697558 0.00544866312042241 BMP2K other 0.000210065916188884 1 1 2.71784288212446 -2.80177383697558 1.04545323066071e-34 1098.20768600505 103.751024315177 10.5850298178155 4.06809395586726e-22 -642.65857931222 204.642614623407 -3.14039468511908 0.00187539484636952 G3BP2 other 1.65087519653633e-30 1 6.28805282758402e-18 10.5850298178155 -3.14039468511908 1.05843321316318e-12 713.757236914377 136.771756889677 5.21860107046886 3.58971335433225e-07 -397.26044387117 226.588498465734 -1.75322422171064 0.0806941560824212 SEPT11 other 1.30293128540387e-08 1 0.00410304236400177 5.21860107046886 -1.75322422171064 0.000922894421576897 106.256153517993 146.321385538694 0.726183347203847 0.468348505546552 -595.193910859648 233.20081434443 -2.55228058500931 0.0112469403752429 FRAS1 other 1 1 1 0.726183347203847 -2.55228058500931 3.40906492744887e-13 865.240801384868 266.691130822329 3.24435536613813 0.00132540421824495 -1786.31099677717 436.118549267692 -4.09592987910433 5.56240375568967e-05 SCARB2 other 4.27019472812246e-09 0.838031749832206 1 3.24435536613813 -4.09592987910433 1.92872421777866e-09 109.214976231494 64.1108855047057 1.70353248706068 0.0896148414628991 -419.244464868193 101.655256313362 -4.12417891678746 4.95260777378902e-05 CCNG2 other 2.05351267466894e-05 0.747744721686666 1 1.70353248706068 -4.12417891678746 3.15019199593075e-17 101.369322484802 47.0593479129798 2.15407409962948 0.0321193318320357 -454.481602861608 75.0276915029659 -6.05751814773139 4.62222381416336e-09 CNOT6L other 4.40176327591404e-13 7.35072253166399e-05 1 2.15407409962948 -6.05751814773139 1.9889793320824e-25 516.803329639344 65.3646969748488 7.90645950425198 6.7957205837839e-14 -468.692549836582 128.832393217061 -3.6380023543218 0.000329092763089468 USO1 other 3.05487335614536e-21 1 9.77088705536449e-10 7.90645950425198 -3.6380023543218 0.0506255923498796 0.538558377348118 7.28880629660484 0.0738884195069061 0.941154084127593 -29.7222577779028 14.3767291731941 -2.06738663710248 0.0396540987247809 CDKL2 other 1 1 1 0.0738884195069061 -2.06738663710248 0.00096589583349667 109.044817768499 93.4231237195066 1.16721442644002 0.244149776732231 -354.035833647794 156.190561256966 -2.26669160286408 0.0241974273903078 SHROOM3 other 1 1 1 1.16721442644002 -2.26669160286408 0.0174010139413607 75.153595512904 162.480414208071 0.462539413622265 0.644062986198249 -511.580229247474 254.58000447462 -2.00950671794994 0.045467412008024 ANXA3 other 1 1 1 0.462539413622265 -2.00950671794994 7.54397635418692e-10 251.932038450031 73.0112686570212 3.45059116331084 0.000649299923919099 -258.339328385913 107.12876674176 -2.41148420021164 0.0165580243606346 PPA2 essential 8.21010946626162e-06 1 1 3.45059116331084 -2.41148420021164 0.000267065571262717 134.013041319036 43.9850329194943 3.0467873370544 0.00254207268455528 -15.8986134010213 64.4347826096262 -0.246739614182327 0.80529724178596 CENPE essential 1 1 1 3.0467873370544 -0.246739614182327 1.37898007787039e-15 101.930845446583 17.1510394502463 5.94312932124467 8.63848247109005e-09 -36.344418774246 25.1655633224977 -1.4442124067914 0.149842935107377 GSTCD other 1.85086706051764e-11 1 0.000107549106765071 5.94312932124467 -1.4442124067914 3.11843241456941e-24 82.5719063906776 16.10625726897 5.12669734574271 5.64229292883189e-07 -116.88704191611 23.6325639834548 -4.94601609871628 1.33596989501836e-06 INTS12 essential 4.75342652952816e-20 0.0208665137902917 0.00635773567220778 5.12669734574271 -4.94601609871628 0.0608964190882281 7.44530632787834 18.3490456384076 0.40575986754832 0.685241605537863 -47.0221290181545 28.4728629355046 -1.65147175837803 0.099809139655777 ENPEP other 1 1 1 0.40575986754832 -1.65147175837803 1.04162084095889e-05 38.8532223369343 26.0053240052714 1.49404876974648 0.136334930078868 -117.474189271075 40.9174130778127 -2.87100724201881 0.00441706142220785 CASP6 other 0.0851733361652081 1 1 1.49404876974648 -2.87100724201881 0.412174900115517 83.6977248168958 71.9208203366598 1.16374819454378 0.245561090686305 19.0506072500325 113.518299629486 0.167819702305373 0.866851691073146 LEF1 other 1 1 1 1.16374819454378 0.167819702305373 3.49507753966126e-10 326.318363774517 85.4871049631405 3.8171647515168 0.000167713337810846 -314.601626393984 134.931035967572 -2.33157348965729 0.0204646221447509 HADH other 3.87149739068278e-06 1 1 3.8171647515168 -2.33157348965729 0.344237371853931 34.9614821480318 24.2547954313889 1.44142556250081 0.1506275820245 24.3761597551614 37.637023715342 0.647664383334991 0.517754411368786 EGF other 1 1 1 1.44142556250081 0.647664383334991 1.59073287639612e-10 150.87742696439 107.6102815339 1.40207259765286 0.162050744460967 -796.736843498797 169.849789326609 -4.69083209733471 4.34105534024114e-06 PAPSS1 other 1.79116521882203e-06 0.0672776756630571 1 1.40207259765286 -4.69083209733471 4.1879854452747e-23 238.334650746765 39.0887643219997 6.09726745986254 3.73278536799588e-09 -241.807201992166 61.7237752181767 -3.91756986894343 0.000113487629488869 SEC24B other 6.32888360489913e-19 1 4.72160021197799e-05 6.09726745986254 -3.91756986894343 7.52757195644219e-10 317.934210526313 86.1335957255619 3.69117541010726 0.000270023884582283 -264.119617224882 128.120677583984 -2.0614909490449 0.0402134600887507 PPP3CA other 8.19300931739168e-06 1 1 3.69117541010726 -2.0614909490449 0.0530379444229871 -19.8294029080582 522.384222227149 -0.0379594215604693 0.969748086452003 -1470.01343728228 765.253804845669 -1.92094887731886 0.0557910923970938 SLC39A8 other 1 1 1 -0.0379594215604693 -1.92094887731886 0.00021508113693339 5.98480225536135 2.39410756950131 2.49980507626397 0.0130177273850234 -3.54999719036307 3.53085442318044 -1.00542156795164 0.315590775608242 MTTP other 1 1 1 2.49980507626397 -1.00542156795164 0.318114186826702 750.074443915519 525.197776123102 1.42817520944664 0.15438863494605 984.421104163052 858.718906305385 1.14638340548306 0.252644033919 FBN2 other 1 1 1 1.42817520944664 1.14638340548306 0.00421094974370741 158.249513935925 109.094279836016 1.45057572380327 0.148054483594174 -330.926319498549 199.695021447995 -1.6571585866237 0.098644605887993 MAPK8IP3 other 1 1 1 1.45057572380327 -1.6571585866237 0.671719362964502 27.992519775448 58.1875662297743 0.481073906148774 0.630852153260166 -49.7583802589975 109.432796532357 -0.454693490760653 0.649693773288018 RGS3 other 1 1 1 0.481073906148774 -0.454693490760653 9.72593500581266e-25 494.059774307063 49.322548159207 10.0169150367556 2.68227235988641e-20 -322.151484692934 142.78736176356 -2.25616245523453 0.024857705556256 GUCD1 other 1.48651190628841e-20 1 4.11085061876191e-16 10.0169150367556 -2.25616245523453 6.34686746350083e-40 257.331494134657 20.3668769518322 12.6348037916293 4.39502631696778e-29 -357.207968690066 64.9351083597272 -5.50099903909002 8.7381787719217e-08 RNF185 other 1.00693052308441e-35 0.00138168082741626 6.92216644922426e-25 12.6348037916293 -5.50099903909002 0.077357454565897 18.4194474178004 11.8848557820224 1.54982506776923 0.122350509126439 -25.0461475206482 26.9735371581452 -0.928545165352367 0.353951146403767 KIAA1644 other 1 1 1 1.54982506776923 -0.928545165352367 0.845388422781106 -13.0997517360652 32.4518850101017 -0.403666897377071 0.686774847397135 16.6649707522316 73.942210649628 0.225378313764487 0.821854220901608 PARVG other 1 1 1 -0.403666897377071 0.225378313764487 0.00123081193949569 332.498172117056 109.4051323165 3.03914601698178 0.00261251663618463 -722.202378946715 491.574327413278 -1.46916211582291 0.142988504471498 B4GALNT3 other 1 1 1 3.03914601698178 -1.46916211582291 0.272287311346704 13.6603506214826 17.9411071002541 0.761399536001273 0.447082970751148 117.501204828718 74.8049853782838 1.57076703156243 0.117407889975762 ERP27 other 1 1 1 0.761399536001273 1.57076703156243 3.51362202273184e-06 357.450032353386 76.1701829698007 4.6927815900758 4.27495292277816e-06 -320.3342137475 337.333428425717 -0.949607085317485 0.343154904270809 ETV6 other 0.0298798416813116 1 0.0452418267817613 4.6927815900758 -0.949607085317485 6.516274049158e-07 368.552936341469 73.9530778059955 4.98360510847582 1.11428390424327e-06 -441.722568541398 335.428307720357 -1.31689114596034 0.188987605821201 GABARAPL1 other 0.00589136336784375 1 0.0123094942901754 4.98360510847582 -1.31689114596034 1.75176052243036e-05 426.099626999523 97.1190119594155 4.3873966425604 1.68754825028532e-05 -123.121916477149 273.116368496759 -0.45080387219124 0.652518549504715 KIF21A other 0.140578781925037 1 0.170020486216246 4.3873966425604 -0.45080387219124 0.761589573095345 6.72050736423505 44.9023214249641 0.149669485918799 0.881145099010124 -80.9338861588141 126.273514497709 -0.640941106935632 0.522143387930586 CPNE8 other 1 1 1 0.149669485918799 -0.640941106935632 1.54165668956833e-40 181.53606798477 11.3477601223656 15.9975242715058 9.7945654824589e-41 18.269623637847 73.5188375271288 0.248502618544606 0.80393874334327 YARS2 essential 2.44660916634495e-36 1 1.55635645516272e-36 15.9975242715058 0.248502618544606 2.65275688167165e-14 126.858355176544 15.1584102416634 8.36884298248305 3.42570816116292e-15 93.4168284316244 98.2069313863939 0.951224390303747 0.342360514078658 FGD4 other 3.44142150259264e-10 1 5.02380101834543e-11 8.36884298248305 0.951224390303747 1.77533954266035e-13 47.4011701259183 5.97072796806694 7.93892643902595 6.35033510200941e-14 5.51142089074702 28.9174061553072 0.190591813842042 0.848995871318479 ALG10 other 2.24527191960254e-09 1 9.13559207775074e-10 7.93892643902595 0.190591813842042 0.138322961512921 18.3347549986822 10.6826913692823 1.7163048491135 0.0872792912185057 -28.6267104503978 47.9028206305409 -0.597599683559064 0.550619319556786 PIK3C2G other 1 1 1 1.7163048491135 -0.597599683559064 4.28448109990801e-18 340.285317725014 36.6046855732118 9.29622293966766 5.49168342152891e-18 -89.1209577263397 166.795876007409 -0.534311518123992 0.59357230365468 AEBP2 other 6.08096402509944e-14 1 8.29683531324588e-14 9.29622293966766 -0.534311518123992 2.28051833069365e-10 40.3558498565525 5.89531953340018 6.84540500780573 5.25277532238642e-11 6.44736261584342 38.2399192921615 0.168602934712914 0.866237103269845 ETFBKMT other 2.55075975288084e-06 1 7.08231696717361e-07 6.84540500780573 0.168602934712914 5.14828330340232e-25 392.809775964413 33.4185489437106 11.75424392681 5.93448829525336e-26 210.957137175768 202.144130532104 1.04359763808361 0.297622651357267 ETNK1 other 7.88511070749099e-21 1 9.29400211919628e-22 11.75424392681 1.04359763808361 3.82929391266023e-08 164.845388493434 38.6217846764558 4.2681970777473 2.75662992951404e-05 -279.921681887517 102.537188505119 -2.72995277097482 0.00676383591713545 ZCRB1 essential 0.000376419591614501 1 0.273071760817661 4.2681970777473 -2.72995277097482 4.45408094213595e-05 75.9781850573916 30.8667332955951 2.4614909627717 0.0144784934064354 -231.354747854822 80.1770538367163 -2.88554813108978 0.00423133857560522 TMEM117 other 0.342741528497361 1 1 2.4614909627717 -2.88554813108978 0.385778019995261 -41.1967844710434 30.2535103780234 -1.36171915114252 0.174456287612733 -52.4247946201691 80.3202110560169 -0.652697421121155 0.514523643524039 PRICKLE1 other 1 1 1 -1.36171915114252 -0.652697421121155 0.0093918850117515 348.523549566558 113.084969968889 3.08196172897638 0.00226831955182053 303.905884255083 520.004402129936 0.584429445232166 0.559417620125881 C1RL other 1 1 1 3.08196172897638 0.584429445232166 7.30157681436101e-19 544.89575590039 56.0057007931652 9.72929091473645 2.25752326183214e-19 22.7619982345285 254.524592650188 0.0894294653319101 0.928806907810761 NDUFA9 other 1.05018579320954e-14 1 3.44362598359874e-15 9.72929091473645 0.0894294653319101 9.96101337868865e-05 298.881163333951 68.4638572074097 4.36553205625703 1.80582469878729e-05 294.195628536094 314.820856780905 0.934485826461094 0.350885248341623 CLSTN3 other 0.738609142029763 1 0.18159373171005 4.36553205625703 0.934485826461094 0.36002881962266 1.40879191794013 1.61502413230249 0.872303942561936 0.383814777544725 9.63798912210043 7.55061112104622 1.27645153055704 0.202888723022165 KLRG1 other 1 1 1 0.872303942561936 1.27645153055704 0.00212853835338197 35.1671887835669 10.3455049444505 3.39927233831454 0.000777676161904602 -17.1722205433138 48.9231747419377 -0.351003806149022 0.725859215549525 VAMP1 other 1 1 1 3.39927233831454 -0.351003806149022 5.30363331712563e-10 206.030060738653 30.5468751109654 6.74471807640627 9.29393803882468e-11 59.6691410467595 144.454051967329 0.413066578847196 0.679885681680452 TAPBPL other 5.81861611221853e-06 1 1.24352890959474e-06 6.74471807640627 0.413066578847196 0.918693585324058 -3.73190715966993 18.2227335764527 -0.204794036197307 0.837887344975404 26.8719671463615 86.1740421394117 0.311833662193636 0.755407602175196 CD27 other 1 1 1 -0.204794036197307 0.311833662193636 0.155630564147559 12.435984370986 6.5424585029101 1.90081211297778 0.058387547535393 0.0758023610804669 30.0845216053173 0.00251964655030676 0.997991468793149 RBP5 other 1 1 1 1.90081211297778 0.00251964655030676 1.9286462733565e-23 420.118907844744 38.5346233350254 10.9023748381338 3.45445002544556e-23 -148.449424122774 177.432309447086 -0.836653846108253 0.403524312458141 PEX5 other 2.92286342727177e-19 1 5.36856078454494e-19 10.9023748381338 -0.836653846108253 0.439873240784456 7.85385227931851 6.53499010079354 1.20181548222465 0.230480336171643 20.7894247878961 30.9306393316572 0.672130458248184 0.502071162096783 PIANP other 1 1 1 1.20181548222465 0.672130458248184 0.644614207231667 30.5053367565501 36.8193428956375 0.828513883124308 0.408125109967634 -15.8250625626527 93.2401073130378 -0.169723770367647 0.865356871906813 SLC38A4 other 1 1 1 0.828513883124308 -0.169723770367647 0.139458405447228 -167.647348160823 110.923800570907 -1.51137399997086 0.131875805184124 -476.633800256629 281.335162616189 -1.69418495656327 0.0913962157013366 AMIGO2 other 1 1 1 -1.51137399997086 -1.69418495656327 2.91128430708074e-07 300.972831916141 83.4356001858339 3.60724716123325 0.000370270638339005 -631.705967505925 210.837188302471 -2.99617905452082 0.0029949208852152 SCAF11 other 0.00270632989186226 1 1 3.60724716123325 -2.99617905452082 0.0690052596155181 79.1421390574832 153.260564832907 0.51638945180561 0.606005095774478 901.433423944885 390.117801392857 2.31066980467554 0.0216049270270084 COL2A1 other 1 1 1 0.51638945180561 2.31066980467554 0.994264797557717 -0.219818573637363 2.05168879103179 -0.10714031026451 0.914758735189445 -0.160140676196404 4.68724379666722 -0.03416521161333 0.9727711271209 PPFIA2 other 1 1 1 -0.10714031026451 -0.03416521161333 4.13361142162568e-21 143.656967453139 15.7770489285846 9.10543968668718 1.97227099787471e-17 -118.876263659293 47.37388941575 -2.50932032656307 0.0126823141225711 LLPH other 6.12725221027575e-17 1 2.96530944530463e-13 9.10543968668718 -2.50932032656307 0.000337912350695943 125.525271387198 70.4202236016168 1.78251736457588 0.075784321175138 -522.091975644018 182.690906651037 -2.85778851949801 0.00459703282276498 LRIG3 other 1 1 1 1.78251736457588 -2.85778851949801 8.85837211713675e-07 102.232234722823 30.2787335293631 3.37637089819765 0.000841258362396526 -224.592534496851 78.9941487289948 -2.8431540577437 0.00480443919017923 MARCH9 other 0.00792027050993197 1 1 3.37637089819765 -2.8431540577437 0.110278077019523 7.42769045563986 7.66702868436902 0.968783444202171 0.333510736545203 -29.638739040567 20.5336761976401 -1.44342098099186 0.150048410817329 INHBE other 1 1 1 0.968783444202171 -1.44342098099186 0.0233124578755546 289.688090362292 115.403671949762 2.51021553706194 0.0126531497599659 -84.9174652005607 271.932721287169 -0.312273803603375 0.755074371632394 GLIPR1 other 1 1 1 2.51021553706194 -0.312273803603375 0.54448614434415 137.689135312254 366.167456793057 0.376027778432726 0.707192627813532 -761.575113392407 868.116763382539 -0.877272672889068 0.381121358451217 PHLDA1 other 1 1 1 0.376027778432726 -0.877272672889068 0.0152081698049356 137.498305692872 66.5364632299083 2.06651058710116 0.0397517972437137 -267.131109472174 190.201322434105 -1.40446504815823 0.161351392677927 TMEM19 other 1 1 1 2.06651058710116 -1.40446504815823 0.390179353343038 -70.2003178820845 96.8455941553484 -0.724868472276367 0.469169866044463 -429.935420202554 327.914411675855 -1.31112084401934 0.19094763399255 LGR5 other 1 1 1 -0.724868472276367 -1.31112084401934 0.0596487547899425 26.2595662140715 12.5497996849014 2.09242911228808 0.0373587969648233 -12.910121362302 28.202102733424 -0.45777158832208 0.647494511248143 PTPRQ other 1 1 1 2.09242911228808 -0.45777158832208 0.0766757244640496 657.014836264699 306.732081368828 2.14198277967108 0.0330829813781584 -110.841854602496 725.611532843824 -0.152756467593733 0.878703583608326 DUSP6 other 1 1 1 2.14198277967108 -0.152756467593733 2.19706108105975e-06 83.0578291711204 18.9532823819905 4.38223984094926 1.67908707485033e-05 -68.8601291003236 44.8362630353004 -1.53581330018759 0.125746555344183 POC1B other 0.019013366595491 1 0.169218395403416 4.38223984094926 -1.53581330018759 0.0050079989787098 206.093010164191 105.405661777439 1.9552366228614 0.0515828533366363 -499.206632972189 249.194301835473 -2.00328269665565 0.0461425500272666 TMTC3 other 1 1 1 1.9552366228614 -2.00328269665565 0.731367601635466 -1585.03952323646 2928.36976773315 -0.54127027969676 0.588767618237816 2784.03151112893 6772.85972050156 0.411057016684049 0.681356787443138 LUM other 1 1 1 -0.54127027969676 0.411057016684049 8.01610818641466e-08 290.433585205806 55.8856518270076 5.19692578883816 3.98231396842063e-07 -145.843485059383 126.765837063944 -1.15049518417029 0.250950420894181 SNRPF essential 0.000772191701597324 1 0.00453665207282478 5.19692578883816 -1.15049518417029 0.00936879948101083 23.8594153907337 8.13086122499969 2.93442659153669 0.00362674505594821 -0.971293768867862 18.4432926080633 -0.0526637943402372 0.958038443444712 AMDHD1 other 1 1 1 2.93442659153669 -0.0526637943402372 0.00789475076196329 215.584570663916 100.511840970063 2.1448673965501 0.0328525431119347 -361.424430336722 226.462166045766 -1.59595943396427 0.11166329555913 NEDD1 essential 1 1 1 2.1448673965501 -1.59595943396427 0.135219971821935 4.50659230918067 5.97503603836461 0.754236841459142 0.451361888808446 -20.631230144117 13.1467580035866 -1.56930173495919 0.117744488158594 SYCP3 other 1 1 1 0.754236841459142 -1.56930173495919 0.0862299211875466 515.705141910311 248.330914798427 2.07668522595713 0.0387694322721988 -81.0711422310118 543.992168093072 -0.149029980551377 0.88164040895523 ASCL1 other 1 1 1 2.07668522595713 -0.149029980551377 0.0211436282680776 26.5082684595593 13.4419058443299 1.97206175720544 0.0496192970641425 -36.4370289835402 27.7376893514287 -1.31362885069096 0.190082141764769 GAS2L3 other 1 1 1 1.97206175720544 -1.31362885069096 0.381290216368777 1.39229057743244 7.42332466332496 0.187556201645211 0.851364396954376 -19.3127391413688 15.1778095298642 -1.2724325669899 0.204306121776421 TMEM132B other 1 1 1 0.187556201645211 -1.2724325669899 0.0641856850096774 9.98006773967546 24.5302455206186 0.406847445994245 0.684441173877354 -110.139563334419 51.4711308914223 -2.13983181303626 0.0332614806897352 SLC15A4 other 1 1 1 0.406847445994245 -2.13983181303626 2.90300449995672e-06 200.494392649641 45.6226185196274 4.39462703271594 1.5901353774655e-05 -119.410300605676 98.3939667209917 -1.2135937251547 0.225951810421097 TDG other 0.0248613305376293 1 0.160603673124016 4.39462703271594 -1.2135937251547 1.09630707745322e-07 112.496953104835 22.8627619833309 4.92053205062696 1.499970259528e-06 -80.8735434322032 48.2961875629867 -1.6745326600931 0.09517955052729 RITA1 other 0.00104774067392204 1 0.0164291742526102 4.92053205062696 -1.6745326600931 0.0166786975254771 35.5098007452893 13.1643259006268 2.69742643970843 0.00742593882228104 -6.81289724576276 27.808834002668 -0.244990395681786 0.806649276763445 SDSL other 1 1 1 2.69742643970843 -0.244990395681786 2.4633820816975e-05 173.42460599537 39.1938223740571 4.42479440612463 1.39992557920455e-05 -15.7037907713552 84.3210113840692 -0.186238169035081 0.852397324534896 MMAB other 0.194779621199821 1 0.141994451498718 4.42479440612463 -0.186238169035081 0.00539322475329575 175.531012389519 267.985931565765 0.655000847857727 0.513022780624499 -1635.12249604384 572.669192741255 -2.85526533777176 0.00463262317006992 GLTP other 1 1 1 0.655000847857727 -2.85526533777176 0.000307549338413139 38.3822867214743 31.8854154015342 1.20375683484517 0.229733988700528 -229.160121322062 68.1371406011106 -3.363218933175 0.000881533239269114 GIT2 other 1 1 1 1.20375683484517 -3.363218933175 1.59035290087293e-05 114.14395255188 37.2133996790843 3.0672809669694 0.0023787548883949 -207.173919616091 79.5227101246138 -2.60521704166578 0.00968885606772597 TCHP other 0.128023408520271 1 1 3.0672809669694 -2.60521704166578 0.153414903823997 57.7027397538489 43.5143806701751 1.32606138166637 0.185935927795985 -89.7936146878428 93.6161967782256 -0.959167513507963 0.338329314814856 FAM222A other 1 1 1 1.32606138166637 -0.959167513507963 5.10888296297404e-16 337.17656488009 57.0312027267282 5.91214192861601 1.0055086306631e-08 -231.653691239505 92.5849234596144 -2.50206710318827 0.0129323977819184 NUP58 other 6.93122151586688e-12 1 0.000124833896496824 5.91214192861601 -2.50206710318827 0.000585706754340736 113.220529336963 48.8631608707887 2.31709384573703 0.0212386895969525 -112.131703171981 79.7155647925075 -1.40664754071366 0.160669249209662 MTMR6 other 1 1 1 2.31709384573703 -1.40664754071366 0.000131041199231696 55.3755647152421 27.1201721218181 2.04185889626757 0.0421336904864802 -89.7642623132024 42.7329617702234 -2.10058602527641 0.0366013091634522 SLC46A3 other 0.957124919188305 1 1 2.04185889626757 -2.10058602527641 2.15757960906183e-07 606.355472332224 181.369737525771 3.34320091435357 0.000945353541408954 -604.992300177153 286.961527294623 -2.10826972479836 0.0359290952544337 SLC7A1 other 0.00202229936757366 1 1 3.34320091435357 -2.10826972479836 2.48730580891195e-07 160.582209926756 49.6822684032224 3.23218353524979 0.00138036940696375 -172.263284928213 77.5564103001864 -2.2211353550462 0.0271684267326278 LNX2 other 0.00232140251145752 1 1 3.23218353524979 -2.2211353550462 0.0132196053586986 42.0640694090073 21.6237046704577 1.94527580033385 0.0527720346364393 -84.2382904048862 57.5640602742075 -1.46338340283183 0.144517117656249 SUOX other 1 1 1 1.94527580033385 -1.46338340283183 0.790900115772542 3.98197636593468 7.51522224760667 0.529854771387871 0.596644854967335 11.0047083425068 18.7385073392617 0.587277745407674 0.557504355033405 CCDC65 other 1 1 1 0.529854771387871 0.587277745407674 0.156826105169755 26.3481591373517 14.071262253077 1.87248014168665 0.0622129807967068 6.59088573836545 37.4588443938992 0.175950055187471 0.860464102854021 SLC39A5 other 1 1 1 1.87248014168665 0.175950055187471 7.66977946761386e-10 174.847120523192 32.113869536772 5.44459833228702 1.15745979851705e-07 -163.845104667985 86.9111452163548 -1.88520245890343 0.0604644309458081 TARBP2 other 8.34548703871064e-06 1 0.0013641821185322 5.44459833228702 -1.88520245890343 0.582577512487424 -7.02693862717487 8.36571032267649 -0.839969154577025 0.401660682825248 -19.2391768500432 22.4048707785983 -0.858705102125423 0.391256557624726 RDH16 other 1 1 1 -0.839969154577025 -0.858705102125423 0.973268329175724 -7.03686833133175 122.823788339029 -0.0572923895809821 0.954354193296243 59.23243351845 310.899076296358 0.190519811843982 0.849043417257705 ACVRL1 other 1 1 1 -0.0572923895809821 0.190519811843982 0.143538007026901 -8.29227145608257 4.25011052310811 -1.95107195706958 0.0520712994215961 -3.77780180538224 11.4980171699143 -0.328561155332697 0.742739294139144 GPR84 other 1 1 1 -1.95107195706958 -0.328561155332697 0.170422473492236 -1.86021509344828 1.72039304130957 -1.08127331881806 0.280529771556562 -8.48264637278926 4.65597362134303 -1.82188454288158 0.0695666466954636 NPFF other 1 1 1 -1.08127331881806 -1.82188454288158 5.12745726026755e-09 178.974690303289 33.1937002417106 5.39182703344392 1.51478732891356e-07 -129.207977360103 88.3643293578778 -1.46221872897159 0.144835693592977 NABP2 other 5.31666043317142e-05 1 0.00177230117482886 5.39182703344392 -1.46221872897159 0.0970435476821241 3.42459489444181 29.5666120346849 0.115826422399171 0.907875890134289 -82.3263141130329 45.8920090000811 -1.79391392764887 0.0739415946139762 N4BP2L1 other 1 1 1 0.115826422399171 -1.79391392764887 7.94533942311737e-10 441.754130251565 89.7196674982273 4.92371564194989 1.47489367182611e-06 -642.708149093137 238.84105089105 -2.69094507286486 0.00756620045460338 SMARCC2 other 8.63896755475552e-06 1 0.0161618848558705 4.92371564194989 -2.69094507286486 1.13178816042701e-11 105.348996110231 21.3208294091484 4.94113029510136 1.36164626918046e-06 -73.074795726383 33.0932639149185 -2.20814712970759 0.0280714537804735 BRCA2 ts 1.34015036076162e-07 1 0.0149640995283348 4.94113029510136 -2.20814712970759 5.09761241267659e-08 193.528926835738 38.9646649626398 4.96678021025711 1.20417543767418e-06 -143.94795814591 98.4146890951917 -1.4626674073692 0.144712901547206 KANSL2 essential 0.000497119162484221 1 0.0132748300249202 4.96678021025711 -1.4626674073692 3.50120838449704e-08 95.9105399883981 31.5545133884529 3.03951890519395 0.00259949177173097 -311.178029395445 80.5522988861352 -3.86305584940923 0.000139926618357064 CERS5 other 0.000344869025872958 1 1 3.03951890519395 -3.86305584940923 2.16549957481831e-06 205.68011677345 57.5798771669587 3.57208328487849 0.000418476817545295 -371.643395140098 155.830896063995 -2.38491470258552 0.017765830341753 MAP3K12 other 0.018759722816651 1 1 3.57208328487849 -2.38491470258552 0.293389800627823 -38.5903445064343 24.8991395590973 -1.5498665893591 0.122331997150428 -50.8884003331332 67.0254804440154 -0.759239620455074 0.448364287577248 ITGB7 other 1 1 1 -1.5498665893591 -0.759239620455074 0.0239711932228069 125.304410217162 132.220156295771 0.947695220816874 0.344125825569583 -685.267820618544 330.628197101214 -2.07262364984789 0.039149185848811 GALNT6 other 1 1 1 0.947695220816874 -2.07262364984789 0.0761267961733177 30.8493362706382 33.4353241431879 0.922657012042856 0.357000681594894 -148.356215354581 90.0038597389912 -1.64833170249376 0.100434943790062 CSAD other 1 1 1 0.922657012042856 -1.64833170249376 0.107295454297132 0.0612432818429472 23.9215123332237 0.00256017600349994 0.997959153969245 -122.261106099899 61.3850269788361 -1.99170892507795 0.0474028593366321 LMBR1L other 1 1 1 0.00256017600349994 -1.99170892507795 3.0029437814016e-18 211.266590995251 28.8311026844174 7.32773190494152 2.65158377148152e-12 -269.795671505458 77.6098509174298 -3.47630704499738 0.000591252307012861 C12orf10 other 4.27529106158146e-14 1 3.7010806282339e-08 7.32773190494152 -3.47630704499738 0.00110358622924375 219.096822794601 107.983378366558 2.02898655430894 0.0434335260786861 -656.799314799637 287.460534429022 -2.28483299839481 0.023092755434561 ESYT1 other 1 1 1 2.02898655430894 -2.28483299839481 0.000365985162216573 1625.2208252415 649.136591474762 2.50366540199064 0.0128754650339491 -3497.2039261709 1657.11459691015 -2.11041766978082 0.0357320098378591 TMBIM6 other 1 1 1 2.50366540199064 -2.11041766978082 4.20587191358185e-06 235.954763499082 71.454271629972 3.30217855583191 0.00108774895481124 -486.246194453746 190.217081746254 -2.5562698680363 0.0111238581190049 ANKRD52 other 0.0355774705169889 1 1 3.30217855583191 -2.5562698680363 0.906224501936959 2.01674682603839 4.57264162675911 0.441046333969489 0.659529813390039 2.37796897694725 12.3190602065141 0.1930316872459 0.847078207748696 KRT71 other 1 1 1 0.441046333969489 0.1930316872459 1.25975525842824e-07 149.57250649998 38.3600641203731 3.89917248393082 0.000121559569210708 -281.053769242479 103.260665752277 -2.72178924273768 0.00691059838317689 ZNF740 other 0.00119840517734279 1 1 3.89917248393082 -2.72178924273768 1.71865096186205e-15 236.869515250523 42.9141673754905 5.51961111532147 7.92258693716212e-08 -237.884555155245 70.1024810557977 -3.39338282429551 0.000793091702156222 WDFY2 other 2.30127363793329e-11 1 0.000941757909220461 5.51961111532147 -3.39338282429551 0.0211401553213718 171.337688898989 75.0980517370745 2.28151975897935 0.023296396199714 306.951269523568 121.946330935075 2.51710131145308 0.0124120415491668 HNRNPA1L2 other 1 1 1 2.28151975897935 2.51710131145308 0.00535015583788948 14.020839062785 99.9203053684764 0.140320218308784 0.88851122688145 -431.53849222796 157.615614212755 -2.73791714344655 0.00659243034914293 LPAR6 other 1 1 1 0.140320218308784 -2.73791714344655 5.9822734114556e-19 424.78874411295 63.4424865253489 6.69565093327833 1.21871683053191e-10 -299.611084218852 99.8072352818274 -3.00189744133113 0.00293140945415839 ESD other 8.61806307654294e-15 1 1.6251588935143e-06 6.69565093327833 -3.00189744133113 1.5628269269806e-11 202.47585367208 91.1131006977975 2.2222474278825 0.0270922929447296 -709.824435415046 143.7230128186 -4.93883631782023 1.37641830640021e-06 RB1 ts 1.84116640267584e-07 0.0214913954361328 1 2.2222474278825 -4.93883631782023 0.779419505496759 2.21030339410181 11.8313197998801 0.18681799084868 0.851942606387338 17.2779603305614 24.5170963224908 0.704731102871731 0.481580572480238 MORN3 other 1 1 1 0.18681799084868 0.704731102871731 6.5886992250798e-07 66.9352215040856 53.4463483735693 1.25238156658027 0.211506597748956 -512.365502439884 110.752586636487 -4.62621703023132 5.76700154695968e-06 SETD1B other 0.00595420748970462 0.0891232419067149 1 1.25238156658027 -4.62621703023132 3.32136418609157e-11 263.239613939652 39.8606625126301 6.60399495006494 2.09411060358773e-10 -85.277408859497 82.6076639048943 -1.03231836888253 0.302840001525257 VPS33A other 3.85743236572675e-07 1 2.77071773960693e-06 6.60399495006494 -1.03231836888253 0.00815765756411271 -15.7559602464357 91.304846174899 -0.172564337015084 0.863122218214255 -576.307049978059 189.377308262385 -3.04316845173222 0.00257006438679668 VPS37B other 1 1 1 -0.172564337015084 -3.04316845173222 0.134012242968758 104.911640284196 57.6623255736977 1.81941396293684 0.0699476078578242 -25.672601644528 119.489018484945 -0.214853230615184 0.830042747923996 RHOF other 1 1 1 1.81941396293684 -0.214853230615184 1.26446273209869e-10 437.108301854499 71.457502546938 6.11703860721101 3.29204041570463e-09 -237.942918648408 148.214406072209 -1.60539670167071 0.109562629918902 DENR essential 1.43124536646251e-06 1 4.17233202286405e-05 6.11703860721101 -1.60539670167071 7.79826530137611e-09 79.8162691829116 17.6972532148349 4.51009364074674 9.80019789684149e-06 -52.2279033596019 29.7170855871103 -1.75750422114932 0.080004245617303 DIAPH3 other 8.00102019921189e-05 1 0.10071663378584 4.51009364074674 -1.75750422114932 0.136536528825169 22.5491842610365 13.2852053909558 1.69731544206214 0.0908865041973432 -5.94272432821486 26.9145532784766 -0.220799664283011 0.825429366687939 SLAIN1 other 1 1 1 1.69731544206214 -0.220799664283011 3.79736740823505e-23 271.544461428073 44.2317164558821 6.13913461167439 3.2867190303036e-09 -422.524824292283 75.4386180458477 -5.60090886123463 5.66995929095871e-08 RBM26 other 5.7401005742881e-19 0.000897441156572944 4.16624504281285e-05 6.13913461167439 -5.60090886123463 4.05450827856404e-07 266.0560367972 76.2899492552166 3.48743234717786 0.000570427544534767 -302.842271215896 135.574182473256 -2.23377538179613 0.0263293286559174 MBNL2 other 0.00373176941959034 1 1 3.48743234717786 -2.23377538179613 0.000143029126155103 20.658691041576 14.094325807325 1.46574524556821 0.143876994169991 -74.6371811401432 25.4280713508568 -2.93522776896048 0.00361875674366386 ZIC5 other 1 1 1 1.46574524556821 -2.93522776896048 3.54681866248194e-09 70.6985057856384 18.0834281692709 3.90957428668177 0.000117299908347911 -101.308749065162 33.1130067608108 -3.05948504758139 0.00244280805393911 ABHD13 other 3.70926295722361e-05 1 1 3.90957428668177 -3.05948504758139 0.0207310689094725 64.2622780616263 23.0735724488099 2.78510309594216 0.00573713968029221 40.190936132188 45.5457962398439 0.882429103238041 0.378344545173834 RAB20 other 1 1 1 2.78510309594216 0.882429103238041 3.74702122382412e-10 134.372783687943 22.8019983293853 5.89302664384351 1.15724205607972e-08 -31.6591565349544 42.7456025210396 -0.740641251211085 0.459571703703095 GRTP1 other 4.145704282039e-06 1 0.000143312856224913 5.89302664384351 -0.740641251211085 4.36124392120083e-31 652.455387247748 63.2215072983051 10.320149188617 3.37525941715902e-21 -438.684065795812 118.407355913353 -3.7048717320977 0.000257605403924323 CUL4A other 6.84628070750106e-27 1 5.19553682083288e-17 10.320149188617 -3.7048717320977 0.0177818751347474 9.97427652733111 6.6765673166196 1.49392285800859 0.136413042636134 -15.6782307754927 12.4538465322401 -1.25890669480353 0.209197519450205 TTC6 other 1 1 1 1.49392285800859 -1.25890669480353 0.222120955295908 13.830876165565 16.8645353620526 0.820116052333484 0.412904059944954 -26.6865011353283 31.2829045319476 -0.853069800730133 0.394408810820517 SSTR1 other 1 1 1 0.820116052333484 -0.853069800730133 2.59677543888687e-06 103.938583530339 32.9946333689734 3.1501663427507 0.00181386758945516 -115.806134574973 64.9975791926067 -1.78169919577783 0.075913931434381 CDH24 other 0.0223270752235493 1 1 3.1501663427507 -1.78169919577783 0.000935903466663711 5.27752415157494 1.89194694932797 2.78946730163313 0.00565257767106993 -2.27598353294609 3.57625084732721 -0.636416076530846 0.525040448682944 REM2 other 1 1 1 2.78946730163313 -0.636416076530846 0.193732614457164 10.0323431820056 6.93162886716888 1.44732838042196 0.148960751353917 -2.29118292092828 13.6266481427974 -0.168139875405774 0.866598653499906 CBLN3 other 1 1 1 1.44732838042196 -0.168139875405774 0.00727083761861019 0.534002785725043 1.43539485715697 0.372025009747297 0.710163897187492 -6.93005759674747 2.81299315727306 -2.46358850139029 0.0143746303290716 TSSK4 other 1 1 1 0.372025009747297 -2.46358850139029 0.19784634427366 8.44419337687987 15.3680196167027 0.549465291396578 0.583143733630621 -33.1929949228198 28.4155314958872 -1.16812859642003 0.243793002790829 NOVA1 other 1 1 1 0.549465291396578 -1.16812859642003 2.29158423998258e-19 478.061078013395 60.0330558811799 7.96329740334384 4.6878620008914e-14 -204.075438486857 114.923911532133 -1.77574393149503 0.0769014240619849 TMX1 other 3.32096388058276e-15 1 6.75849064668512e-10 7.96329740334384 -1.77574393149503 2.77388374481075e-07 667.571813939922 158.843922029089 4.20269032275387 3.58864156783093e-05 -431.212926509189 304.081885800034 -1.41808159790471 0.157320051251252 FRMD6 other 0.00258054404779744 1 0.351507441569039 4.20269032275387 -1.41808159790471 1.59273266656964e-05 148.934462002873 37.8751172142931 3.93225085377871 0.000106853797773736 -22.3478046820887 70.3254678065344 -0.317776836459411 0.750898042210669 PELI2 other 0.128183125005525 1 0.999083009184432 3.93225085377871 -0.317776836459411 0.420383401156592 -59.268647753218 78.2547382459379 -0.75738094691403 0.449477274608093 -190.5860306611 145.085559418683 -1.31361130235652 0.19008396146333 RTN1 other 1 1 1 -0.75738094691403 -1.31361130235652 3.80969163921268e-09 84.8486307677751 14.5709503876138 5.82313634393413 1.6306797889475e-08 16.6598420521623 27.0388883185492 0.616143750286261 0.538316828860795 C14orf37 other 3.97808000966588e-05 1 0.000200459466455316 5.82313634393413 0.616143750286261 0.0207331663694967 6.68512293801039 3.15926797772502 2.11603541869352 0.0352503839449849 -2.87244320193122 5.65652343446174 -0.507810713632189 0.611997627679632 SYT16 other 1 1 1 2.11603541869352 -0.507810713632189 4.12009551283583e-10 59.5183009316592 11.919092351369 4.9935262834693 1.06095290559011e-06 -31.5924116869941 21.3271830324877 -1.48132135588978 0.139678444412806 SLC38A6 other 4.54899745572204e-06 1 0.0117434518862019 4.9935262834693 -1.48132135588978 1.29862378143687e-28 204.3941645531 22.0190133851864 9.28262138623381 5.52352652778944e-18 -113.666518283751 40.8600419306071 -2.78185026037887 0.00578454454638699 NAA30 other 2.02273640196606e-24 1 8.34439152553151e-14 9.28262138623381 -2.78185026037887 0.393151863758328 -15.4850785117506 27.7963395756828 -0.557090564733834 0.577925354512165 -68.6552885823944 50.3992794546592 -1.36222758192721 0.174257202871627 RDH12 other 1 1 1 -0.557090564733834 -1.36222758192721 2.07505501915369e-15 346.514437775152 54.1783743807402 6.39580721525549 6.97043189988846e-10 -218.193033588782 98.6779733713557 -2.21116249284584 0.0278595188628004 DCAF5 other 2.7733110330989e-11 1 9.05598512433509e-06 6.39580721525549 -2.21116249284584 1.29127158700042e-06 124.251899517757 52.3716038537678 2.37250514352576 0.0183611368144006 -285.678833294228 97.0835706677138 -2.94260739823853 0.0035341439414435 RAB15 other 0.0114032193848007 1 1 2.37250514352576 -2.94260739823853 6.85805072641887e-23 90.6701459318835 10.2621137675392 8.83542591572984 1.2457000905139e-16 -28.4008400108678 19.089937447403 -1.48773876756371 0.137973917747097 WDR89 other 1.03433121055849e-18 1 1.85870910505579e-12 8.83542591572984 -1.48773876756371 0.00525447033088143 9.61227997625695 3.51430483184759 2.73518673996286 0.00664432251262266 -1.35560506705152 6.53416172194966 -0.207464266226799 0.835802536693605 ESR2 other 1 1 1 2.73518673996286 -0.207464266226799 2.110949737209e-10 422.998920492929 63.9261175325648 6.61699688358905 1.93078522152077e-10 141.756684033896 121.296935365524 1.16867490185731 0.243554125340407 STON2 other 2.36510808556896e-06 1 2.55848349703718e-06 6.61699688358905 1.16867490185731 2.23701268801165e-21 47.8415446442227 5.25679290131039 9.10089964402003 2.03639091823454e-17 -14.0180461112735 11.3616668629753 -1.23380189547316 0.218349646029306 EFCAB11 other 3.32599046453572e-17 1 3.06110282829017e-13 9.10089964402003 -1.23380189547316 0.539881650476539 -7.66138065380169 11.0278910177531 -0.694727635725461 0.487823397424545 -23.6755507353641 21.7741187173292 -1.08732532612314 0.277862754843855 GPR65 other 1 1 1 -0.694727635725461 -1.08732532612314 1.74657250867976e-14 82.112429021547 15.2095643113609 5.39873643587624 1.45914163952393e-07 -98.4893898079396 29.7202785763908 -3.31387841990746 0.001044470548175 PTGR2 other 2.27491069255538e-10 1 0.00170850894571857 5.39873643587624 -3.31387841990746 0.801536250344876 30.3445661416577 46.2928999912623 0.655490715582417 0.512709979259651 17.3001164309743 86.7577976565734 0.199407049259779 0.842094435729213 JDP2 other 1 1 1 0.655490715582417 0.199407049259779 0.101134769152264 10.0814122125152 8.93776044511938 1.12795730814427 0.260339262839553 -23.8017130780629 20.168010289904 -1.18017160522661 0.238970674977846 AK7 other 1 1 1 1.12795730814427 -1.18017160522661 0.129115198268041 5.30435938749539 10.8291780912254 0.489821050389165 0.624653908366556 43.6869423226166 22.0196947654116 1.98399400119023 0.0482578849251248 FAM181A other 1 1 1 0.489821050389165 1.98399400119023 0.27257647600428 -10.9903334218412 9.84148153726583 -1.11673566426205 0.265092862234068 -32.6111736687241 21.2544560414495 -1.53432172553027 0.126112844302306 SLC24A4 other 1 1 1 -1.11673566426205 -1.53432172553027 0.311659044199481 -143.221799867267 98.6451806927248 -1.45188846390171 0.147685079860104 -220.425209791081 211.188602572161 -1.04373629592896 0.297534141915819 FBLN5 other 1 1 1 -1.45188846390171 -1.04373629592896 0.045300891707657 598.721986740571 459.561185596982 1.30281234687567 0.193748877533954 -1360.41742871603 1013.1962347202 -1.34269885940873 0.180497220786258 WARS essential 1 1 1 1.30281234687567 -1.34269885940873 1.61237760394181e-29 109.278258213266 10.8934195752861 10.0315844311354 2.52092128060894e-20 -77.8913502182577 24.1563265493818 -3.22446999791245 0.00141785828561989 WDR20 other 2.52127485928381e-25 1 3.86381604678933e-16 10.0315844311354 -3.22446999791245 2.66337180420492e-17 311.586304001282 45.3112623795764 6.87657521856479 4.48269363048372e-11 -223.313323240728 94.6051377873131 -2.36047775484214 0.0189845137770082 NIPA2 other 3.72525814254143e-13 1 6.05253293987912e-07 6.87657521856479 -2.36047775484214 0.000253713013696174 269.326141130658 113.292190234047 2.37727014169524 0.0181460960065039 -338.938489732047 201.957092919395 -1.67826979895836 0.0944644503941535 SLC12A6 other 1 1 1 2.37727014169524 -1.67826979895836 0.00115790782048879 -54.9874255807588 55.6461563463976 -0.988162151550267 0.323951445119835 -361.721167010815 99.7493394850406 -3.62630137581073 0.000343193742516007 DUOXA1 other 1 1 1 -0.988162151550267 -3.62630137581073 6.85597886217428e-16 212.323116297049 32.5817562095435 6.51662589737434 3.49110184991798e-10 -126.605063423254 58.5330298478522 -2.16296787903078 0.0314181561247235 MFAP1 essential 9.26791222588719e-12 1 4.58172206783236e-06 6.51662589737434 -2.16296787903078 4.32924794051681e-08 542.67010863529 93.4056240141279 5.80982263501831 1.75024928390539e-08 175.790465286099 180.892543764472 0.971794976331277 0.332019125961047 TCF12 other 0.000424136420732432 1 0.000214808094613709 5.80982263501831 0.971794976331277 2.25045183393105e-05 754.20568901411 166.145564717343 4.53942716013641 8.4781375021089e-06 307.852112154553 297.826686101329 1.03366194676663 0.302212382881441 SORD other 0.178753389169143 1 0.0875706822592828 4.53942716013641 1.03366194676663 2.82128223819981e-09 1014.05824758819 485.441504307842 2.0889401474521 0.0376460649630941 -3813.94984251431 872.094244346297 -4.37332302929389 1.7466507050786e-05 SERF2 other 2.97278509439114e-05 0.267237557877026 1 2.0889401474521 -4.37332302929389 1.65922066134357e-11 122.771795747118 23.4285696426179 5.24025997403566 3.21964580588079e-07 -82.1185234943676 41.5314921591356 -1.97725916467714 0.04902190258193 ZSCAN29 other 1.95190718600458e-07 1 0.00369164588102292 5.24025997403566 -1.97725916467714 0.0956346229923846 -62.6568379593673 43.0388434463899 -1.45582067132947 0.146595426750273 -163.253724621683 77.1499145287397 -2.1160583990131 0.0352484117158219 DUOXA2 other 1 1 1 -1.45582067132947 -2.1160583990131 0.340670272829257 -302.368684589857 234.77659705142 -1.28789959641349 0.198875524453842 -521.116651999526 420.852256832305 -1.23824131518718 0.216694237273712 DUOX2 other 1 1 1 -1.28789959641349 -1.23824131518718 0.000291667229930873 51.9396234185799 16.9893572997714 3.05718589009124 0.00245924720664411 -38.7261416399249 33.1737403541672 -1.16737338709713 0.244093335896836 LYSMD2 other 1 1 1 3.05718589009124 -1.16737338709713 0.0249299831903398 35.4804055085745 19.8887690558393 1.78394175169717 0.0755519694045831 -42.5444259536592 38.0247144077783 -1.11886247184953 0.264189568202565 SLC27A2 other 1 1 1 1.78394175169717 -1.11886247184953 0.757996507953627 -10.6357860700123 29.2767413767574 -0.363284490344816 0.716675590873463 -41.585520866911 55.9732845464733 -0.742953021318296 0.458153667986387 FGF7 other 1 1 1 -0.363284490344816 -0.742953021318296 0.543904309265692 -8.62520725017 9.43495623625494 -0.914175650018027 0.361437194117445 -17.1418026870418 18.0383972143388 -0.950295222095215 0.34280898219486 HDC other 1 1 1 -0.914175650018027 -0.950295222095215 0.44865927628799 -82.6014267282988 67.4895258654579 -1.22391475816509 0.222043493287962 -24.4819978377542 131.756817849595 -0.185811999996093 0.852730685443813 GCNT3 other 1 1 1 -1.22391475816509 -0.185811999996093 6.9008676969995e-11 192.006867481844 47.9961620861094 4.00046293571071 8.154355667234e-05 -358.587892389481 93.7007854828591 -3.82694649294139 0.000161019954697016 BNIP2 other 7.90701420722203e-07 1 0.772154314257551 4.00046293571071 -3.82694649294139 4.96760831714244e-07 203.219923859041 48.0764034658138 4.22702010152542 3.23632330240849e-05 -148.736826001948 93.8574371812395 -1.58471007166684 0.114194135837717 GTF2A2 essential 0.00453989724103648 1 0.318046716809762 4.22702010152542 -1.58471007166684 3.76279881329543e-12 497.781622864392 156.665365436069 3.17735589789642 0.00165700054452813 -1185.87758921718 271.753921186308 -4.36379200727033 1.81480429366301e-05 SRP14 essential 4.53643024930897e-08 0.277501724544011 1 3.17735589789642 -4.36379200727033 7.84056143266606e-08 193.65199984144 48.2926780183608 4.0099660608553 7.84356210525105e-05 -142.369497237808 83.769150759954 -1.69954566742329 0.0903554699238509 BAHD1 other 0.000755673310880355 1 0.74419717254622 4.0099660608553 -1.69954566742329 0.513991016129706 19.0388472668173 17.3028296001765 1.10033143172277 0.272157023955527 7.60735386328501 30.013728805843 0.253462470874463 0.80010162931534 DISP2 other 1 1 1 1.10033143172277 0.253462470874463 2.00189536990191e-16 144.943178696422 23.0816030790285 6.27959757388403 1.33782951551519e-09 -106.432190326018 40.8333028146585 -2.6065045683204 0.00965152936480263 CDAN1 essential 2.74239646722862e-12 1 1.7216528035165e-05 6.27959757388403 -2.6065045683204 0.0672200806350925 211.888142607034 102.435238128879 2.06850832269698 0.0395442163507709 -36.0275860380281 194.492920619394 -0.185238547106457 0.853181008673295 TLE3 other 1 1 1 2.06850832269698 -0.185238547106457 2.84741491832077e-12 850.831220563181 123.826045902218 6.87118137677642 4.39039950407313e-11 -89.8051427227981 237.726621360768 -0.377766453789423 0.705900893382807 ANP32A other 3.44651101713546e-08 1 5.93099069005239e-07 6.87118137677642 -0.377766453789423 4.78622442196448e-11 268.841539783891 48.7417764185474 5.51562867703752 8.25530716732559e-08 -201.146282951646 95.1686382952333 -2.11357739855064 0.0354860051291867 COMMD4 other 5.52713196248458e-07 1 0.000979574748474855 5.51562867703752 -2.11357739855064 0.00447328435993181 195.130272114331 68.5141197061637 2.84803005498992 0.00474121597873275 -60.4076982236104 133.159100127521 -0.453650544091694 0.650448865115027 UBE2Q2 other 1 1 1 2.84803005498992 -0.453650544091694 0.379248180514012 12.4859085802979 12.9972050771643 0.960661042598709 0.337578957257321 32.9176157806892 25.3805209068093 1.29696375821262 0.195746788337773 PSTPIP1 other 1 1 1 0.960661042598709 1.29696375821262 9.38633755451078e-13 565.172296593216 87.9495165041336 6.42609896060831 5.89563236719337e-10 -277.111773001363 171.994499109365 -1.61116648751166 0.10831179522099 ETFA other 1.15836791760217e-08 1 7.67906115826936e-06 6.42609896060831 -1.61116648751166 0.833469492945285 -14.5190439502585 57.3269468493441 -0.253267350665206 0.800252940420989 48.1031662955496 112.950556814975 0.425878080214759 0.670533483249748 BCL2A1 other 1 1 1 -0.253267350665206 0.425878080214759 7.236468269011e-10 186.185232878437 32.0815354932903 5.80350129804032 1.80367183391769e-08 -63.9371143943178 62.6926214679058 -1.01985070806218 0.308705502546956 HMG20A other 7.88051394495298e-06 1 0.000221130166838309 5.80350129804032 -1.01985070806218 0.000344870375580683 57.7167067274294 16.8631585294714 3.42265101917646 0.000716331161972208 -21.5481423847503 32.9776742381742 -0.653416072616991 0.51404412903531 SCAPER other 1 1 1 3.42265101917646 -0.653416072616991 1.72184436003549e-05 526.794936444207 209.214282666018 2.5179683228662 0.0123800902516778 -1156.28157457839 408.546871706858 -2.83022990666307 0.00499959490580692 TSPAN3 other 0.13828132055445 1 1 2.5179683228662 -2.83022990666307 5.2862345908886e-08 277.598077444643 59.2483493186634 4.68533015074563 4.42137820210835e-06 -209.895248792753 114.015481589473 -1.84093638746803 0.0667199147824548 WDR61 essential 0.000515037836190277 1 0.0467118607052747 4.68533015074563 -1.84093638746803 1.96339021159464e-11 238.627386220802 42.5756258711522 5.60478868691131 5.12696507047268e-08 -347.853682221292 135.632665806998 -2.56467481599366 0.0108663373271852 NCOA2 other 2.30325305722167e-07 1 0.000615492156710245 5.60478868691131 -2.56467481599366 0.00451376024719531 63.6378257234642 40.3748819958237 1.57617366485546 0.11617879429749 -164.575521871229 78.9985184212695 -2.08327352411357 0.0381848557025797 NEIL1 other 1 1 1 1.57617366485546 -2.08327352411357 0.000203585993028307 350.692038051959 91.8757295337253 3.81702588737789 0.000167285943789784 -50.8871021115544 176.802487658034 -0.287818925998251 0.773704525140272 DNAJA4 other 1 1 1 3.81702588737789 -0.287818925998251 0.0660898685061449 373.956556730568 229.253745032469 1.63119061229558 0.104003141686536 -409.903254200014 454.821305453605 -0.901240221786021 0.368254990911477 TPM1 other 1 1 1 1.63119061229558 -0.901240221786021 1.83446999972721e-18 1093.64758056488 116.315374666331 9.40243354502516 2.26123235259382e-18 -265.141753771628 449.020787470936 -0.590488817377503 0.555351468083986 IGF1R other 2.6220079706101e-14 1 3.42667150712068e-14 9.40243354502516 -0.590488817377503 0.0194629659711403 48.6365356889266 40.1865798953683 1.21026809983728 0.227226711460131 -224.12453510876 106.036083087013 -2.11366290213535 0.0354545095495934 ARRDC4 other 1 1 1 1.21026809983728 -2.11366290213535 0.000359495171075279 64.0848656288168 17.4424074905613 3.67408373319425 0.000287440137614239 -2.19057215414959 34.3635717728152 -0.0637469285390915 0.949218558945826 PIF1 other 1 1 1 3.67408373319425 -0.0637469285390915 2.5376161145393e-11 183.46293355129 33.0527252661427 5.55061442207971 6.75825597955449e-08 -142.617109932214 65.6007123435014 -2.17401770251268 0.030566133702529 USP3 other 2.96139800566736e-07 1 0.000805651695322691 5.55061442207971 -2.17401770251268 0.570168486800849 0.996054034447494 17.9213686531062 0.0555791275614908 0.95571835029102 33.3534082290719 33.6757967246538 0.990426700273258 0.322855644457308 CYP11A1 other 1 1 1 0.0555791275614908 0.990426700273258 0.0125046496817901 37.229033232261 26.1344009534374 1.4245221575421 0.155458764787757 -90.2600126475549 48.4974973635084 -1.86112722417447 0.0638211106880167 BBS4 other 1 1 1 1.4245221575421 -1.86112722417447 0.0121229601497223 469.571853455333 156.771760413159 2.99525789732676 0.00299770662493785 358.629148248535 295.287081550233 1.21451011796981 0.225618052885335 PML other 1 1 1 2.99525789732676 1.21451011796981 0.698829803883044 -287.259390672715 472.427898891351 -0.60804916760172 0.543669800316396 -693.684775588637 882.333883005805 -0.786193060188842 0.432448974402197 CYP1A1 other 1 1 1 -0.60804916760172 -0.786193060188842 0.000742035344458863 72.5648304314986 20.6458598343161 3.51474005024903 0.000515145252672846 182.155914579927 80.269090845415 2.26931578097389 0.0240294794197712 ADAMTS17 other 1 1 1 3.51474005024903 2.26931578097389 8.8259373040483e-12 76.0115524029228 11.9365836882007 6.36794868518871 8.12526527386765e-10 -54.0863263512242 29.1256510201506 -1.85699973929526 0.064392118691265 LINS1 other 1.04913916733222e-07 1 1.05303437949325e-05 6.36794868518871 -1.85699973929526 1.1875953299266e-05 178.40160846635 53.241008859215 3.3508307278342 0.000921600682152792 -192.250054024378 99.9975547893596 -1.92254755058105 0.0555967275059256 ULK3 other 0.0966346319961275 1 1 3.3508307278342 -1.92254755058105 0.00538208491272662 107.057446918762 43.8034920487982 2.44403909166642 0.0151641180562312 -142.353896078661 106.899671789872 -1.33165886943489 0.18409542262513 PCSK6 other 1 1 1 2.44403909166642 -1.33165886943489 0.779837148003774 -7.90137284428279 11.2384703209752 -0.703064796063557 0.482623389128533 -4.90641996304845 21.1180546168621 -0.232332951688213 0.816456080776504 CCDC33 other 1 1 1 -0.703064796063557 -0.232332951688213 0.0583486028235484 14.3015383556319 10.5554093522263 1.35490134758397 0.176589980700003 -25.2801374356149 19.6166151838385 -1.28871047317288 0.198610101669162 CELF6 other 1 1 1 1.35490134758397 -1.28871047317288 2.51425260741789e-08 273.636690437393 82.1172491770713 3.33226810663548 0.000982675703436039 -524.377382183051 154.233067698799 -3.39990243342046 0.000776753835316308 SCAMP2 other 0.000250092706859857 1 1 3.33226810663548 -3.39990243342046 0.975606813317246 10.4736938749645 48.0258053455124 0.218084710909344 0.827526633230003 11.1461934159035 103.139924028933 0.108068660325722 0.914020901745664 HAPLN3 other 1 1 1 0.218084710909344 0.108068660325722 0.516279925722785 -436.929000211872 582.89597820538 -0.749583144418133 0.454153616288527 738.565344052354 1243.18557399403 0.594090986496519 0.552945037108258 RHCG other 1 1 1 -0.749583144418133 0.594090986496519 7.91023542925389e-12 448.105293203702 61.2256709115013 7.31891192913861 2.82355895789154e-12 97.3002586572185 130.580538691701 0.745135987583445 0.456832879006873 POLG other 9.41476220789798e-08 1 3.9388647462587e-08 7.31891192913861 0.745135987583445 1.27689776997579e-15 754.448339696561 91.0494027279401 8.28614265544265 5.45695778019649e-15 -72.2146679580669 194.517981605813 -0.371249317733557 0.710741910791818 FANCI other 1.71551215396247e-11 1 7.98352923242747e-11 8.28614265544265 -0.371249317733557 0.000507508975384617 1622.82508652064 441.948817840531 3.67197517226124 0.000289901022880858 -243.924140176558 944.179637029458 -0.258345054913473 0.796336712065088 ABHD2 other 1 1 1 3.67197517226124 -0.258345054913473 0.00924306024541644 6.28753325172439 2.25294370729385 2.79080796886698 0.0056298784391353 10.234197338685 4.80502048504696 2.12989671335085 0.0340778417158871 WDR93 other 1 1 1 2.79080796886698 2.12989671335085 5.80507741446006e-11 213.716462840463 31.8020136721553 6.72021794102884 1.06095840002955e-10 -18.5497959285768 67.8265181086121 -0.273488842503644 0.784685018061452 TICRR other 6.67700004211196e-07 1 1.41659165571946e-06 6.72021794102884 -0.273488842503644 0.569970422622515 -27.6240878467707 28.2981302504425 -0.976180673503639 0.329845515452508 -39.9968040144216 57.1452430399634 -0.699914846568255 0.484580865889675 NTRK3 other 1 1 1 -0.976180673503639 -0.699914846568255 6.19396581858017e-05 26.400394722003 7.19859936042537 3.6674349272916 0.000294845998097453 -19.4443264753741 14.8609973698479 -1.30841329094274 0.191841761798045 DET1 other 0.470307824604792 1 1 3.6674349272916 -1.30841329094274 0.232555669299275 225.875363045993 142.900292133186 1.58065011396528 0.115120186119673 -42.6558595558369 306.891788035499 -0.138993160517227 0.889558406580633 MFGE8 other 1 1 1 1.58065011396528 -0.138993160517227 0.0282580742695229 64.0213474311705 27.2707141207885 2.34762269691966 0.0196132019484067 -29.7488379897205 58.495478395212 -0.508566453439853 0.611469906075715 ZNF710 other 1 1 1 2.34762269691966 -0.508566453439853 8.52837895466614e-16 577.653150597057 73.658964795156 7.84226539435489 1.0316679874427e-13 -312.909883078861 177.230063853584 -1.76555758247295 0.0786003519176007 UNC45A essential 1.15107530751129e-11 1 1.48013406158404e-09 7.84226539435489 -1.76555758247295 0.588960176596645 -1.93328572885851 14.2884298144439 -0.135304281433653 0.892472490078812 -35.7607195076337 35.2443077857667 -1.0146523440042 0.311183322715039 ST8SIA2 other 1 1 1 -0.135304281433653 -1.0146523440042 3.84331818996858e-11 220.894412611902 31.0809269305818 7.10707287158012 1.05003686531912e-11 42.4007815863414 78.9100260032747 0.537330726320908 0.591480104253129 MCTP2 other 4.4528684548976e-07 1 1.44390569350032e-07 7.10707287158012 0.537330726320908 0.000185116164456024 1135.5506320939 281.665431716393 4.03155838177998 7.20014237607015e-05 -4.76425007899881 680.181859441405 -0.00700437686313984 0.994416495953198 FURIN other 1 1 0.685885562744442 4.03155838177998 -0.00700437686313984 1.29484939517488e-09 1393.16694551101 239.350997496676 5.82060221215646 1.6412279690237e-08 -808.736933147852 577.871525179304 -1.3995099220314 0.162795368986881 IQGAP1 other 1.39092722029686e-05 1 0.000201706917393012 5.82060221215646 -1.3995099220314 2.10208581429602e-12 234.930676087192 34.7547308781184 6.75967473064523 8.35721477567435e-11 -135.116247139194 83.9092777961513 -1.61026588105603 0.108495440761372 CRTC3 other 2.56013031323113e-08 1 1.11961606349709e-06 6.75967473064523 -1.61026588105603 1.5729423924295e-11 162.9652542116 24.1890755631854 6.73714271493805 9.71808601639029e-11 -24.2358118872771 47.9344670293424 -0.505603032415933 0.613547856192688 EFL1 other 1.85292613828195e-07 1 1.29950246211171e-06 6.73714271493805 -0.505603032415933 0.241476849673079 13.0577335189887 13.5064020542174 0.966781046985892 0.334521875566408 43.0278185019429 26.3367733259209 1.6337543695831 0.103480234566012 SH3GL3 other 1 1 1 0.966781046985892 1.6337543695831 1.29661657480851e-07 344.295940721989 72.9720615150403 4.71818848986506 3.85520859401273e-06 -259.803648577057 145.255029637673 -1.78860345989475 0.0748209127878356 SEC11A other 0.00123256371601297 1 0.0409461704770092 4.71818848986506 -1.78860345989475 7.46614020597058e-18 397.237212973595 62.746174377265 6.33085948133161 9.97589625524611e-10 -369.374936216356 121.681828985105 -3.03558008042081 0.00263254797758406 GLYR1 other 1.05526425671188e-13 1 1.28898555514035e-05 6.33085948133161 -3.03558008042081 2.07059806529822e-12 236.491993192392 49.7457774475184 4.75401140211127 3.25866545353414e-06 -279.037523441223 95.3747884104928 -2.9256948098301 0.00373126908113531 PMM2 other 2.52240256314629e-08 1 0.0347764777201163 4.75401140211127 -2.9256948098301 1.04816163142933e-13 197.333615159655 44.5583773185608 4.42865353351761 1.39765036559485e-05 -351.555579402397 91.3453746834488 -3.84864127626264 0.000149543684319343 SLC5A2 other 1.33525310227782e-09 1 0.141791629589597 4.42865353351761 -3.84864127626264 0.00278650573533732 -237.899716443813 68.7289390630219 -3.46141988639847 0.000626900032092944 -266.058764575031 140.899335169651 -1.88828970878167 0.0600876260114759 ITGAX other 1 1 1 -3.46141988639847 -1.88828970878167 0.949409966697016 -5.13214721455517 39.2078292593323 -0.130895979489444 0.895958430356772 -25.7822579689885 80.344722975791 -0.320895474078081 0.748546395888056 TGFB1I1 other 1 1 1 -0.130895979489444 -0.320895474078081 1.13935445994269e-14 347.110910580845 72.8152497700109 4.76700844503321 3.11553986622796e-06 -573.267077049146 149.272407865264 -3.84040885551057 0.000154368183860198 C16orf58 other 1.49244040707893e-10 1 0.0333082367098431 4.76700844503321 -3.84040885551057 8.48605149430942e-09 105.661681462175 24.3972850444747 4.33087867234246 2.11681290687211e-05 -94.8215932935352 50.0355131580966 -1.89508585619835 0.0591818207110507 ARMC5 other 8.68462509927626e-05 1 0.21153311378373 4.33087867234246 -1.89508585619835 3.18284435993041e-18 252.500081616302 42.4453709038174 5.94882495404446 8.31274189303891e-09 -305.375665226322 83.4647011000474 -3.65874029621546 0.000304538219432217 PARN other 4.52823267087299e-14 1 0.000103576763987265 5.94882495404446 -3.65874029621546 5.38743324886306e-11 128.0112866427 48.585415959255 2.63476774079804 0.0089004752544357 -337.607473727877 86.9241326909044 -3.88393261199836 0.000129012212075719 FTO other 6.2041681293907e-07 1 1 2.63476774079804 -3.88393261199836 1.2776785857575e-15 812.367628772249 149.541112061216 5.43240328746316 1.24483195562079e-07 -956.798599766426 286.831570529134 -3.33575065674035 0.000970472812171114 UQCRC2 essential 1.71643341210663e-11 1 0.00146417134620117 5.43240328746316 -3.33575065674035 0.0785820852427452 -71.9381874175102 38.1573239360684 -1.8853048378875 0.060470386301923 -149.416698579167 73.4505998438095 -2.03424749283052 0.0429112508735393 IGSF6 other 1 1 1 -1.8853048378875 -2.03424749283052 4.81852363215463e-11 183.535740860216 35.0695205323345 5.23348303809838 3.35303568624754e-07 -150.447727584777 75.078353568897 -2.00387622308094 0.0460859180562035 ARHGAP17 other 5.56346738568574e-07 1 0.00383956116432206 5.23348303809838 -2.00387622308094 0.416500644318917 -40.2478083358379 251.043723739965 -0.160321906225098 0.872748728898046 -526.140181344555 449.226447034571 -1.1712137271029 0.242557034546211 NKD1 other 1 1 1 -0.160321906225098 -1.1712137271029 3.14075384139888e-16 345.680067658667 67.0365837973748 5.15658835932812 4.88140408152194e-07 -383.565320643248 114.736984795709 -3.34299634356082 0.000946476087285513 DHX38 other 4.28493046582049e-12 1 0.00551940359497686 5.15658835932812 -3.34299634356082 2.27820776857206e-18 97.0334616233172 17.3025094462317 5.60805713904406 5.07252114704855e-08 -104.807647320444 29.6142442052312 -3.53909580113243 0.000472875713878549 TXNL4B other 3.24895209876062e-14 1 0.00060920978976053 5.60805713904406 -3.53909580113243 9.00605549207323e-11 131.744758231346 34.2959057305176 3.84141358640705 0.000152398111259259 -172.043490664246 59.4184883009341 -2.8954538491943 0.00409453615927564 MARVELD3 other 1.02669032609635e-06 1 1 3.84141358640705 -2.8954538491943 0.159771827186435 1.42615312237248 16.806293976478 0.0848582753799568 0.932436718429966 -45.4229954655865 29.1173118409533 -1.55999962200149 0.119926977947907 CHST4 other 1 1 1 0.0848582753799568 -1.55999962200149 0.000361458809991574 151.630652704624 75.5028581418792 2.00827699025236 0.0456096695826176 -235.011411759746 130.210138640321 -1.80486261833203 0.0722102439329742 ZFHX3 other 1 1 1 2.00827699025236 -1.80486261833203 0.379124480089734 -0.219047844868858 3.92458789595822 -0.0558142283153976 0.955530927182598 -7.85865033929013 6.65074557089303 -1.18161945236388 0.238392585161321 CLEC18B other 1 1 1 -0.0558142283153976 -1.18161945236388 3.51269508456682e-08 263.268323570557 74.7171651755863 3.52353201505803 0.000499358800800093 -259.782375261105 134.391289268058 -1.93302986135463 0.0542703730949435 CPNE2 other 0.000345965338878986 1 1 3.52353201505803 -1.93302986135463 0.0238144264750829 -18.3289858636708 88.4184336067379 -0.207298242187747 0.835932057466785 -373.625476693901 159.035306807309 -2.34932408529003 0.0195229763172206 NLRC5 other 1 1 1 -0.207298242187747 -2.34932408529003 9.12281822591118e-19 121.802480708153 28.5060157542296 4.27286933952111 2.66820751027214e-05 -232.103569565418 49.8431434967177 -4.65668000214919 5.02282801875369e-06 KATNB1 essential 1.309033187236e-14 0.0777383092462508 0.264579456718585 4.27286933952111 -4.65668000214919 0.00049614746429389 42.6599334749524 87.4501410762209 0.487820064667138 0.626068830838569 -441.052222579287 152.907721936678 -2.88443393828035 0.00423375163205568 KIFC3 other 1 1 1 0.487820064667138 -2.88443393828035 0.17776194442284 160.818940913843 87.7236335218341 1.83324532349445 0.0678548752825077 195.355853867021 146.22436231993 1.33600072359757 0.182661635722278 ADAMTS18 other 1 1 1 1.83324532349445 1.33600072359757 2.42318871025429e-12 52.3640728545528 8.93691639209444 5.85929984763804 1.33988824473417e-08 -10.5022085994147 14.8944679031405 -0.705108008403596 0.481346380224724 NUDT7 other 2.94296268860384e-08 1 0.000165422602694881 5.85929984763804 -0.705108008403596 1.11618851069763e-15 92.359544905356 13.3173441592831 6.93528257591625 2.933002772116e-11 -8.64839692517833 22.2932040154055 -0.387938715278519 0.698363702175382 GCSH other 1.50194325999473e-11 1 3.98096466259304e-07 6.93528257591625 -0.387938715278519 0.146426762977904 57.6215471613354 59.8115917969393 0.963384277699226 0.336207272112901 -93.258376782213 104.501659534697 -0.892410486086577 0.37295888095303 CMTM3 other 1 1 1 0.963384277699226 -0.892410486086577 0.669695004558964 -52.9764622994196 186.212408043417 -0.284494802768824 0.776246893714295 -274.501567262899 320.058931482979 -0.857659450373742 0.391832840648357 CDH11 other 1 1 1 -0.284494802768824 -0.857659450373742 3.81716044715447e-06 113.779024808912 53.5633178384317 2.12419673389379 0.0345625905667746 -252.863382362117 93.2834008054096 -2.71070072680555 0.00714437065900651 NOL3 other 0.0323847892336585 1 1 2.12419673389379 -2.71070072680555 2.0920321406209e-11 230.891957589035 77.0467139349866 2.99677878259501 0.00297945960387009 -468.627093406115 127.294305481334 -3.68144585599575 0.000279463495073846 MAP1LC3B other 2.45060644952333e-07 1 1 2.99677878259501 -3.68144585599575 3.83231976724064e-19 645.926128663419 120.749459771274 5.34930864193466 1.86980596076063e-07 -785.08038755491 208.288026315707 -3.76920556328545 0.000200717348346841 MBTPS1 essential 5.53386974389549e-15 1 0.00217533225474891 5.34930864193466 -3.76920556328545 0.00126010019242108 344.058574468392 110.537365099472 3.11259974542341 0.00205140754756761 30.0040691792642 190.401961428171 0.157582773592294 0.874902067238568 CDH13 other 1 1 1 3.11259974542341 0.157582773592294 1.70083177981667e-15 212.003080923432 55.7016121095295 3.80604928465189 0.000174487457503496 -386.11916048655 92.2567815499491 -4.18526588506125 3.84882519150555e-05 ZCCHC14 other 2.27775391953048e-11 0.583097016513091 1 3.80604928465189 -4.18526588506125 2.45195805135466e-12 138.185707813688 45.5880312030339 3.03118393506082 0.00266989817908623 -315.624752794963 78.4423920257235 -4.0236502819988 7.42539304337701e-05 TLDC1 other 2.97716746595483e-08 1 1 3.03118393506082 -4.0236502819988 0.000858904490441886 19.8373126607952 12.3244590621371 1.60958891264761 0.108643316593935 -39.8215123899907 21.2899570561477 -1.87043648256171 0.0624931625853294 ADAD2 other 1 1 1 1.60958891264761 -1.87043648256171 0.00318664628684468 792.925607602445 245.368566993231 3.23156962327746 0.00138207476020451 392.389693074512 422.650353446445 0.928402614300032 0.354018876472638 OSGIN1 other 1 1 1 3.23156962327746 0.928402614300032 0.0661225190553102 -134.783563126441 61.1360632614585 -2.20464903914432 0.0283128866359048 -197.444088905619 102.103220903939 -1.93376944583735 0.0541750756609663 IRF8 other 1 1 1 -2.20464903914432 -1.93376944583735 1.15715865838461e-08 402.865791792021 97.6139573501521 4.12713307326427 4.8931640315085e-05 -282.8856032019 178.683239224461 -1.58316809360357 0.114549439735084 RHOT2 other 0.000117382174306534 1 0.472581782163091 4.12713307326427 -1.58316809360357 0.982570020893613 0.0422863822492072 3.52335735195506 0.0120017296076264 0.990433098304023 1.03866362680176 6.45637502708155 0.160874116271909 0.872312851193006 RPL3L other 1 1 1 0.0120017296076264 0.160874116271909 5.07282468887846e-21 92.2301203869165 12.013545461574 7.6771774562239 2.9073208402603e-13 -45.3494679972563 21.5344394370517 -2.10590427161197 0.036125773114383 ZSCAN32 other 7.512853364229e-17 1 4.14467658987508e-09 7.6771774562239 -2.10590427161197 1.68796881180162e-06 2685.55047189286 631.255146649143 4.25430269542897 2.89423994299583e-05 -192.512589528734 1156.74328699038 -0.166426372812255 0.867945982227769 RPS2 essential 0.0147646631968288 1 0.286240330362287 4.25430269542897 -0.166426372812255 2.30351924499285e-16 277.561575602834 51.2910812269325 5.41149784647333 1.37944685121367e-07 -275.790854691856 93.9883250167132 -2.93430970966675 0.00363022556321471 NDUFB10 essential 3.15167503099921e-12 1 0.00161836704584388 5.41149784647333 -2.93430970966675 1.64164518180729e-18 214.363898447223 40.5269044357749 5.28942196379535 2.53191443299104e-07 -304.856415092649 75.0078144264077 -4.0643287292653 6.31596184226254e-05 PDPK1 other 2.3477167745026e-14 0.949415384128905 0.00292385478721805 5.28942196379535 -4.0643287292653 0.0119053764838275 28.6433654771806 15.6443597628045 1.83090685150837 0.0682043454621937 -29.5626581835876 28.0427221856472 -1.05420072943982 0.292723127941273 TIGD7 other 1 1 1 1.83090685150837 -1.05420072943982 6.71712240390698e-16 229.089878442223 43.5054119035813 5.26577886332723 2.9196306832478e-07 -208.998309348028 70.8911933551529 -2.94815617365871 0.00348626481002306 DEF8 other 9.08289291456302e-12 1 0.00335582350732502 5.26577886332723 -2.94815617365871 3.92224743394229e-12 128.617896542974 83.8102926766485 1.53463127779782 0.126085711590937 -719.200366928874 136.567185628764 -5.2662750837079 2.91251101160757e-07 TCF25 other 4.7239548094401e-08 0.00458691359218077 1 1.53463127779782 -5.2662750837079 2.26688648586173e-07 187.584615039181 63.1209391029469 2.97182864680198 0.00322819571090992 -227.537115207581 103.820979251246 -2.19162944569172 0.0292637124956583 GALNS other 0.00212112568482082 1 1 2.97182864680198 -2.19162944569172 4.26381232291178e-10 61.9014850348602 18.8253197834892 3.28820363992706 0.00114681974368402 -94.0188317886879 30.6754798162033 -3.0649506495747 0.00240537849501617 GAS8 other 4.70127946724253e-06 1 1 3.28820363992706 -3.0649506495747 2.16890745808322e-21 143.623050588823 16.7016058294646 8.59935577784067 6.35967974723859e-16 -80.1145699725222 43.0262079728932 -1.86199467131742 0.0636782216104623 MED9 other 3.22494849942395e-17 1 9.40978215401421e-12 8.59935577784067 -1.86199467131742 7.73974482910581e-21 840.954300181516 94.3328795595416 8.9147527787564 7.16474994581401e-17 -369.461044066635 246.642855305067 -1.49795964537329 0.135299076993758 NCOR1 other 1.14370209339697e-16 1 1.07120176439865e-12 8.9147527787564 -1.49795964537329 1.36338034179633e-21 575.984317531953 63.1403872114602 9.12228041305725 1.66531933101719e-17 -195.596473034782 165.664476302782 -1.18067842545371 0.238758137343914 COPS3 essential 2.03089135713981e-17 1 2.50547293351536e-13 9.12228041305725 -1.18067842545371 1.87757330791494e-21 124.875402270141 16.1992479680437 7.70871601672388 2.39656509225762e-13 -116.704251617171 40.5792297949167 -2.87596024387309 0.00434678148518179 GID4 other 2.79307805285426e-17 1 3.42037769967007e-09 7.70871601672388 -2.87596024387309 1.64005273657407e-08 19.570847207347 5.73698759987465 3.41134556535814 0.000744273753093987 -49.9298633950745 14.7877929956041 -3.37642428521394 0.000841101725582396 ZNF287 other 0.000164890902135157 1 1 3.41134556535814 -3.37642428521394 0.214059225215093 -13.6538150112656 9.35427007122125 -1.45963446718008 0.145557363229375 -40.2152177994744 26.7949277351338 -1.50085188499105 0.134566698209791 MYOCD other 1 1 1 -1.45963446718008 -1.50085188499105 5.10015178032186e-07 228.427632530952 52.9514436375105 4.31390755074966 2.30786374939403e-05 -169.704508054665 124.294952472012 -1.36533708472899 0.173369528233513 KSR1 other 0.00465490852989977 1 0.23007093717709 4.31390755074966 -1.36533708472899 2.5277468406864e-18 418.301955521473 57.849013562642 7.23092633322975 4.98545113131959e-12 -189.839335979791 104.964834512403 -1.80859939294583 0.0716297956418864 UTP4 other 3.60229202266219e-14 1 6.90883817778269e-08 7.23092633322975 -1.80859939294583 4.65134589605271e-13 114.709299704427 27.4554562416159 4.17801469751411 3.97433660300949e-05 -158.106836524666 48.0603184821427 -3.28975840190098 0.00113598418589726 RANBP10 other 5.79929806319852e-09 1 0.387577305525486 4.17801469751411 -3.28975840190098 3.39193970363984e-12 16.6960545982377 4.05731642698404 4.11504867779033 5.14590335502084e-05 -22.963859172557 7.2956736277549 -3.14759956985955 0.00183069435959281 CTRL other 4.0967847740562e-08 1 0.49632237859176 4.11504867779033 -3.14759956985955 0.670986693420577 28.9679341148208 41.6158733906545 0.69607896590069 0.486980351727711 -7.14576562481507 74.5519789907378 -0.0958494425171845 0.923711514433137 DPEP3 other 1 1 1 0.69607896590069 -0.0958494425171845 7.53363962647479e-13 74.2495307275985 23.2411446898748 3.19474499721805 0.00156562561472886 -170.78984939042 40.6832363612983 -4.19803989716245 3.65848435532494e-05 GFOD2 other 9.32739922153844e-09 0.554516473736602 1 3.19474499721805 -4.19803989716245 1.4886745086252e-21 429.802907177784 54.0842701474798 7.94691147732558 5.10902279666237e-14 -204.383700752476 99.7526222909659 -2.0489055431176 0.0414308090465623 NOB1 essential 2.21693407824464e-17 1 7.36159094771081e-10 7.94691147732558 -2.0489055431176 3.51355741120506e-21 363.76204074598 40.0277930986745 9.08773660964151 2.12569792058094e-17 -38.0889921669773 103.990625294248 -0.366273325688755 0.714444820126864 PRPSAP2 other 5.21306513100495e-17 1 3.19449883504904e-13 9.08773660964151 -0.366273325688755 1.96194735031395e-08 102.755678471519 24.3595165158735 4.21829712443431 3.36718325029129e-05 -163.900668657057 51.9431919650983 -3.15538307247627 0.00178494685555108 PCTP other 0.000196312451872414 1 0.330522707848593 4.21829712443431 -3.15538307247627 8.01038825791456e-14 253.671911585448 39.6601653932042 6.39613852011104 7.06262842016512e-10 -239.792044857383 81.9548239134512 -2.92590519272687 0.00372882598354601 TOM1L1 other 1.02420824265696e-09 1 9.17435431779449e-06 6.39613852011104 -2.92590519272687 1.13921420218826e-19 181.524713043346 20.2556783485733 8.96167039777919 5.24125768703644e-17 -96.3283132367241 44.5389050305398 -2.16279033287129 0.0314287328401617 C17orf80 other 1.65755666418393e-15 1 7.84459038018744e-13 8.96167039777919 -2.16279033287129 0.00671786432326405 70.698114704153 57.9677236734649 1.21961171189676 0.22367247993019 -307.652610674595 128.057990507814 -2.40244758999105 0.0169587173904123 TOB1 other 1 1 1 1.21961171189676 -2.40244758999105 1.04771281470007e-23 353.161425750069 34.2916807018553 10.2987493911595 3.56824656250397e-21 -193.791848402781 103.29983762543 -1.87601309796322 0.0617403441894223 VPS53 other 1.59074236655911e-19 1 5.49117463503735e-17 10.2987493911595 -1.87601309796322 0.0331208978672113 112.57597097738 65.921856890149 1.70771844556767 0.0888296024477781 -310.380708493385 203.407226874528 -1.52590796926229 0.128194700305557 SGSM2 other 1 1 1 1.70771844556767 -1.52590796926229 7.15258917645248e-10 410.982057231243 73.4941514529672 5.59203758538872 5.4930845182523e-08 -261.388591986238 158.285576818577 -1.6513734052082 0.0998249062573121 NPEPPS other 7.79417642558027e-06 1 0.000658785626273998 5.59203758538872 -1.6513734052082 0.00220119833384754 16.5910092377146 19.4033393701951 0.855059478225666 0.393270743022976 -125.187842964749 42.4947477370354 -2.94596037466635 0.00349828495224447 SKAP1 other 1 1 1 0.855059478225666 -2.94596037466635 0.743582157032073 8.83537925980202 17.7934285047729 0.496552941296953 0.619908369040474 27.1750754484706 37.6224313438138 0.722310453573037 0.47072876098154 LRRC46 other 1 1 1 0.496552941296953 0.722310453573037 2.06698390732024e-06 117.790216196408 23.8020099384033 4.94875081983559 1.31626445867141e-06 2.50521860499572 50.3269779914616 0.0497788403949219 0.960335432730309 SCRN2 other 0.0179393533316324 1 0.0144723277230921 4.94875081983559 0.0497788403949219 3.34014307708566e-05 98.7974858525716 37.2196071668442 2.65444730272655 0.00842994027219197 -172.876679357057 77.4497234882228 -2.23211486847135 0.0264530327651607 SSH2 other 0.260397554289598 1 1 2.65444730272655 -2.23211486847135 0.0103063426853776 69.2268070033946 26.8203306469638 2.58113175093281 0.0103837571580835 -14.0838925269472 52.548361459788 -0.268017729491427 0.788893389832644 RHBDL3 other 1 1 1 2.58113175093281 -0.268017729491427 7.12231890449011e-09 110.618048066554 18.2474575465189 6.06210743521672 4.52628360969365e-09 -11.9505696698926 41.0477629473353 -0.291138147655582 0.771170022111751 ARSG other 7.31889490625404e-05 1 5.70221209149207e-05 6.06210743521672 -0.291138147655582 0.88698850010193 -15.9925108932462 35.8098088279193 -0.446595818762863 0.655524899705894 6.0921270535241 78.5065468088132 0.0776002422875667 0.938203524292171 ABCA8 other 1 1 1 -0.446595818762863 0.0776002422875667 1.08931916224063e-09 203.278624804665 44.0584212602096 4.61384268864513 6.09482627059849e-06 -239.345125232095 91.4366431913765 -2.61760621210849 0.00935072910118377 G6PC3 other 1.17395926114672e-05 1 0.0636726500489424 4.61384268864513 -2.61760621210849 2.79565857818602e-10 1832.25015580631 299.086072403591 6.12616341871596 3.1569159047545e-09 -865.186749669645 639.892781863055 -1.35208080821078 0.177476749376164 CLTC other 3.11184756337886e-06 1 4.00423213359061e-05 6.12616341871596 -1.35208080821078 3.53081908480068e-11 296.97767127646 45.1534188486894 6.57708051458168 2.51703740720458e-10 -111.350551665569 97.1991306886415 -1.14559205289869 0.252989740626231 BCAS3 other 4.09610322027727e-07 1 3.32022404384357e-06 6.57708051458168 -1.14559205289869 9.91026547321093e-16 189.997314231852 23.5318482485986 8.07404978243333 2.26358693739511e-14 -50.9631122282517 49.4248069602925 -1.03112415328592 0.303405358987815 PTRH2 other 1.33491275924151e-11 1 3.28061654836673e-10 8.07404978243333 -1.03112415328592 2.77933797661107e-23 582.705403103496 67.033249263268 8.69278170919277 4.38428945784026e-16 -456.561551117723 149.107984996405 -3.0619523906029 0.00243430306047993 SS18 other 4.20597216000553e-19 1 6.50409341070602e-12 8.69278170919277 -3.0619523906029 3.46879662931434e-12 205.826524014316 29.3153717003065 7.02111254527138 2.00488649137061e-11 5.90664441169737 65.240424340938 0.0905365725524717 0.927932186824794 TAF4B other 4.18822505023413e-08 1 2.73506615152778e-07 7.02111254527138 0.0905365725524717 2.09700700476482e-18 690.0793265669 84.9085627559849 8.12732313642016 2.00876976117033e-14 -354.253167135873 192.708159093155 -1.83828836725396 0.0672015342965661 AFG3L2 essential 2.99284839720035e-14 1 2.91331878462532e-10 8.12732313642016 -1.83828836725396 3.0101508481292e-05 24.445241887687 7.0213726424497 3.48154743132367 0.000587829945774198 -23.4716346866203 15.935681306043 -1.47289809803862 0.142031384292926 PRELID3A other 0.235664709900035 1 1 3.48154743132367 -1.47289809803862 2.56507535188065e-09 773.06093387791 132.159931417201 5.84943504122684 1.52511829259789e-08 -119.984853108925 299.905738518622 -0.400075215971484 0.689440039024495 IMPA2 other 2.70820655651559e-05 1 0.000187772564184652 5.84943504122684 -0.400075215971484 0.000138586688519376 19.3429776330542 36.2499468315374 0.533600165620818 0.594077592768489 -299.838401632294 81.2586871299653 -3.68992426806911 0.000273621159423441 GNAL other 1 1 1 0.533600165620818 -3.68992426806911 1.62536045381462e-06 670.361535550257 173.43710571148 3.8651563793127 0.000139813210876852 -514.180837098222 313.495755310001 -1.64015246901756 0.102164399888595 SLC39A6 other 0.0142381575754161 1 1 3.8651563793127 -1.64015246901756 5.48292015646254e-21 835.180722184266 93.7038450139988 8.91298240813379 8.36673582287014e-17 -233.935540763851 169.374122957187 -1.38117639624905 0.168392671098672 RPRD1A other 8.1152701235802e-17 1 1.25049233608617e-12 8.91298240813379 -1.38117639624905 7.61633601002859e-18 88.3625343857121 12.6955494909729 6.96011893368946 2.6849506645522e-11 -69.2087074802741 22.9478049718435 -3.01591840985191 0.00281184269921011 C18orf21 other 1.07618827821704e-13 1 3.64992193339226e-07 6.96011893368946 -3.01591840985191 0.00156218173115493 500.878937312355 238.31247113909 2.10177392277561 0.0365206945688999 -775.073024073224 430.761040626595 -1.79931087302089 0.0731113977614711 GALNT1 other 1 1 1 2.10177392277561 -1.79931087302089 0.145828127183871 3.37656496160687 8.02770877974545 0.420613783365712 0.674376731709304 -22.5980431521148 14.4633131142586 -1.56243890826346 0.119373529004187 ASXL3 other 1 1 1 0.420613783365712 -1.56243890826346 0.499639018451282 -0.784662637813207 9.72179984007167 -0.0807116635521496 0.935734570085725 -23.5695820288099 21.1935544067905 -1.11211086051984 0.267137848247142 ADCYAP1 other 1 1 1 -0.0807116635521496 -1.11211086051984 2.53368911820384e-08 207.632949558071 39.1847550522652 5.29881963741068 2.43520818747335e-07 -34.3901172297667 75.9854975691488 -0.45258790598128 0.651211655741635 GAREM1 other 0.000251924709023008 1 0.00281388306062545 5.29881963741068 -0.45258790598128 1.13659150696612e-13 192.177201945876 27.8709628220121 6.89524804626045 5.22560147430266e-11 -96.0140206531204 61.4926395159904 -1.56139045922973 0.119818577306345 ESCO1 other 1.44642635176509e-09 1 7.04620102794971e-07 6.89524804626045 -1.56139045922973 1.18312145801283e-15 335.128302799572 44.7811221845849 7.48369595157072 1.24319256658131e-12 -143.638426266749 105.301126809802 -1.36407302199333 0.173776290777203 OSBPL1A other 1.59047017600665e-11 1 1.74792874861333e-08 7.48369595157072 -1.36407302199333 0.434749034667401 -15.0022313991368 29.7907522479864 -0.503586860588616 0.615029548795122 -85.6988563127464 66.2768148978429 -1.29304427867936 0.197281859650264 GATA6 other 1 1 1 -0.503586860588616 -1.29304427867936 0.00350055412033034 26.905836921771 7.92284223669034 3.39598292102438 0.000807179042648829 18.2309200644276 17.5489355427725 1.0388618739862 0.299974259895247 GREB1L other 1 1 1 3.39598292102438 1.0388618739862 6.37597253127198e-22 216.287518817773 26.0032334855739 8.31771629238978 6.86033471317028e-15 -196.771313548586 59.9969691240257 -3.27968756458048 0.00119411979777206 C18orf8 other 9.53526692051724e-18 1 1.00202048820565e-10 8.31771629238978 -3.27968756458048 3.59125660831653e-27 893.225253398633 73.0047450639156 12.2351670787511 1.0169305449811e-27 345.929464288375 218.425644406537 1.58374015664812 0.114414829401656 PELP1 essential 5.56249736062147e-23 1 1.5980046583833e-23 12.2351670787511 1.58374015664812 2.30933742290836e-13 694.686321599141 106.890080783698 6.4990719111243 4.66152459778873e-10 -465.170872704963 246.626285150346 -1.88613663957753 0.06048908686381 NPC1 other 2.91022702034912e-09 1 6.09261264930987e-06 6.4990719111243 -1.88613663957753 0.434356726388095 -73.8042402426388 131.940360411835 -0.559375766537764 0.576367291971699 -291.680764444842 225.513260712316 -1.29340848304675 0.196971205853247 SLC14A1 other 1 1 1 -0.559375766537764 -1.29340848304675 0.809853104147716 0.138466544017707 53.0355953522504 0.00261082284639296 0.997918780895395 -98.7185894648658 158.679193813464 -0.622126865485053 0.534379591776406 ARRB2 other 1 1 1 0.00261082284639296 -0.622126865485053 1.96947566613912e-05 265.934352761012 57.1837340876229 4.65052443678336 5.16372701850251e-06 55.6427192223189 171.310269802992 0.324806675550206 0.745576148791045 SLC13A5 other 0.157242937184547 1 0.0542604435104244 4.65052443678336 0.324806675550206 0.233094103640073 -12.8213558306809 7.55334391720393 -1.69744102363435 0.0907571081578358 -15.6077895639663 22.5991339480061 -0.690636623504035 0.490382851279669 ZMYND15 other 1 1 1 -1.69744102363435 -0.690636623504035 1.36055040236806e-10 177.731470395554 26.1179204610148 6.80496254136491 6.39047215132739e-11 16.6145925105991 77.055389324028 0.215618825060147 0.82944588505483 WRAP53 other 1.53674167947472e-06 1 8.59965837404127e-07 6.80496254136491 0.215618825060147 1.40332359858073e-09 604.052768904936 122.204351870448 4.94297264916808 1.34989357430804e-06 -1015.38054682993 362.654386924532 -2.7998573392171 0.00548018514321756 MINK1 other 1.50422256531868e-05 1 0.0148366802752196 4.94297264916808 -2.7998573392171 3.87113744242999e-09 204.628639844579 33.1793740239841 6.16734479971384 2.49233768459454e-09 -8.19886616064498 97.8887115749452 -0.0837570137427725 0.933311009283226 SAT2 other 4.0387576936872e-05 1 3.17274587248885e-05 6.16734479971384 -0.0837570137427725 0.960475428106034 1.09407585834411 3.85321386682582 0.283938524088562 0.77667351058197 0.805073386502121 11.5285755899946 0.0698328583802521 0.944378006351446 ASGR1 other 1 1 1 0.283938524088562 0.0698328583802521 0.269628320863974 -38.5179267400361 24.6567682015713 -1.56216445014807 0.119411948444302 -69.8012939208867 74.5370726597642 -0.936464116849683 0.349864984037708 PIK3R5 other 1 1 1 -1.56216445014807 -0.936464116849683 0.00147002345580164 536.504695529581 163.61563830465 3.27905511409989 0.00117718167932971 -304.131410402179 482.095606707626 -0.630852897580176 0.528666421621713 TP53 ts 1 1 1 3.27905511409989 -0.630852897580176 0.000152364667358763 51.8410552050052 12.281617447298 4.22102833176995 3.32544043281305e-05 18.4524999925555 27.6398770379724 0.667604272161012 0.504956440754595 CCDC40 other 1 1 0.326524996097913 4.22102833176995 0.667604272161012 3.27621063993719e-09 1246.87289020033 195.88602490713 6.36529783475609 8.41179734343682e-10 477.011529719709 434.687977178637 1.097365362658 0.273466697585826 ARHGDIA other 3.43314112959018e-05 1 1.08966422786881e-05 6.36529783475609 1.097365362658 0.0573567343056651 227.526967744086 95.1315810770782 2.39170804445831 0.0174497058316961 186.041878270358 210.660624626838 0.883135510491867 0.377942921266875 TMC6 other 1 1 1 2.39170804445831 0.883135510491867 0.0790890878701975 21.5941617707051 18.8279865520217 1.14691827036526 0.252430733088695 -64.9170659369129 42.3725323967787 -1.53205537325515 0.126679598971753 CARD14 other 1 1 1 1.14691827036526 -1.53205537325515 0.00735667871961868 60.7014993357374 19.887144876406 3.05229834211915 0.00249485136698778 -1.29915254936587 44.4172267613812 -0.0292488442906441 0.976687496127484 TTYH2 other 1 1 1 3.05229834211915 -0.0292488442906441 2.3082535421787e-05 170.118056679858 44.2203399973556 3.8470544706357 0.000150462359434902 -109.77259720554 96.3378228149685 -1.13945482675454 0.255562173017979 RAB40B other 0.183090670965614 1 1 3.8470544706357 -1.13945482675454 2.00270177663877e-18 997.305562784937 107.66138248185 9.26335460120128 6.44926664259307e-18 -53.7869984307149 242.292791344932 -0.221991740373913 0.824488129476669 EIF4A3 essential 2.85965786686249e-14 1 9.73516799699424e-14 9.26335460120128 -0.221991740373913 9.29413932544595e-10 633.696925361111 105.008694633434 6.03470910264365 5.41317781762829e-09 -119.743062326423 228.717222502455 -0.52354195725308 0.601039698868811 CSNK1D other 1.00571881640651e-05 1 6.79732738559585e-05 6.03470910264365 -0.52354195725308 1.51427826084325e-11 564.354483638442 81.2225964312206 6.94824480421945 2.82400322458063e-11 26.2349599576003 180.621663539732 0.145248136040057 0.88462454852201 ANAPC11 essential 1.7851826417081e-07 1 3.83414917801313e-07 6.94824480421945 0.145248136040057 1.63464724080691e-06 451.560948624692 107.558077802409 4.19829879680669 3.70045595636669e-05 -346.654913331366 232.052348995139 -1.49386513358944 0.136428125424279 TBCD essential 0.0143146058877461 1 0.362015606211353 4.19829879680669 -1.49386513358944 2.07951328263167e-14 243.63262574502 37.0537278556019 6.57511780446097 2.65040357617142e-10 -204.670125227317 80.724740447507 -2.5354076593211 0.0118182343848649 FN3KRP other 2.70399112140597e-10 1 3.49323191339393e-06 6.57511780446097 -2.5354076593211 1.26171252642808e-11 406.569314574863 65.8253563522961 6.17648482446355 2.48883350279544e-09 -227.854702598117 143.372820009687 -1.58924615267191 0.113210782861242 NARF other 1.49172271999591e-07 1 3.16853393240888e-05 6.17648482446355 -1.58924615267191 6.82386315758837e-17 307.77606443341 34.9936380426833 8.7952005463965 1.74872589542024e-16 3.54798196553153 78.1279041920361 0.0454124810107628 0.963812226399634 RPTOR essential 9.45923910904899e-13 1 2.60595132935524e-12 8.7952005463965 0.0454124810107628 4.33375272717554e-16 722.795089838801 89.1879182858803 8.10418163951282 2.06159795891786e-14 -143.595555306687 194.137029821051 -0.73966082328059 0.460170577204578 FOXK2 other 5.89087008204971e-12 1 2.98972936002268e-10 8.10418163951282 -0.73966082328059 0.000381078423335624 104.350641768227 25.9447660103118 4.02203056010422 7.4875169829421e-05 64.1155360258551 59.5849185847915 1.07603631168206 0.282868026617603 TRIM65 other 1 1 0.711987989907964 4.02203056010422 1.07603631168206 1.02413377586898e-08 70.1967982905835 12.3202316527607 5.69768493556322 3.15126295085905e-08 -23.9561304087984 27.6914369521844 -0.865109688968623 0.387740933383911 CBX8 other 0.000104287542396739 1 0.000381901557014608 5.69768493556322 -0.865109688968623 0.747255946286485 -14.539361543174 46.1157423794817 -0.315279789351132 0.752800198740204 -76.620348667351 100.44372561237 -0.762818664881493 0.446257801239806 SECTM1 other 1 1 1 -0.315279789351132 -0.762818664881493 0.0194016613409436 43.0283047585914 18.9176971522399 2.27450013668797 0.0237176811894174 -45.796550374534 43.3990451288274 -1.05524327179526 0.292253925681205 RNF157 other 1 1 1 2.27450013668797 -1.05524327179526 2.40433721689432e-08 160.833234588318 27.4959005399375 5.84935322830069 1.43896103012776e-08 16.4307101968792 61.1567034396915 0.268665727103522 0.78839440024428 CEP131 other 0.000239327726569661 1 0.000177366336573547 5.84935322830069 0.268665727103522 0.0447569180107466 83.8012616971143 84.3850252027607 0.993082143375039 0.321596798060623 -325.415587363325 182.057393720699 -1.78743406522977 0.0750365474730607 ZNF750 other 1 1 1 0.993082143375039 -1.78743406522977 9.83094675777805e-13 984.359230846404 143.887339439708 6.84118029202194 5.56736520498863e-11 -345.153544672088 313.202295159978 -1.10201473618126 0.271470436204052 WDR45B other 1.21215573523403e-08 1 7.50146787720168e-07 6.84118029202194 -1.10201473618126 1.1561806449563e-05 156.667051515126 38.5661316111925 4.06229624206484 6.36192949315503e-05 -120.463553493283 86.6827533848912 -1.38970612710463 0.165754527897666 CBX4 other 0.0941709135316907 1 0.608773033200005 4.06229624206484 -1.38970612710463 0.00299921789054694 58.4759177725549 34.664110227273 1.68692972036961 0.0927675554878866 -120.597044201472 59.6968374350883 -2.02015800807881 0.0443507641363187 RNF165 other 1 1 1 1.68692972036961 -2.02015800807881 6.93345021972334e-22 368.071080511425 48.4488589321631 7.59710524920286 5.03134029970167e-13 -231.284108487544 77.3876669461495 -2.98864299202202 0.00306120307445235 DYM other 1.03641213884425e-17 1 7.13494367900694e-09 7.59710524920286 -2.98864299202202 0.257698958036034 96.184962665135 58.7548364002808 1.63705608862312 0.102788044249194 95.087172123301 93.2392237199292 1.01981943145433 0.308730408048038 MAPK4 other 1 1 1 1.63705608862312 1.01981943145433 1.45108699996547e-16 52.7866283744973 8.79186762171677 6.00402902383439 6.21238711195568e-09 -40.0969174803754 13.9519903776523 -2.87392095285565 0.00437773722973604 ELAC1 other 1.99422886405254e-12 1 7.78163609643568e-05 6.00402902383439 -2.87392095285565 6.71449603213689e-14 258.664433998828 72.124020192996 3.58638402721687 0.000397900420422648 -520.869259741421 114.118223582505 -4.5642951965936 7.61861897014938e-06 MBD1 other 8.60462666518343e-10 0.117501960376614 1 3.58638402721687 -4.5642951965936 2.29001359915541e-25 569.720850086156 79.6662449783575 7.15134559487433 8.12882015551971e-12 -569.528431935671 126.423955772061 -4.50490912467979 9.90833331975736e-06 SMAD4 ts 3.51494187334364e-21 0.152439708124467 1.12104558764772e-07 7.15134559487433 -4.50490912467979 0.000110727943339109 35.4816653564082 15.3407089246657 2.31290910548199 0.0214712435011552 -56.0044929299892 27.2207382895281 -2.05742005724857 0.040595532745226 TNFRSF11A other 0.816507854182589 1 1 2.31290910548199 -2.05742005724857 2.7020894581436e-20 149.640210215708 20.9206865426708 7.15273898447334 7.82614210673432e-12 -110.161353479005 37.1219176383469 -2.96755557059932 0.00326789795259879 ZCCHC2 other 3.96423544404247e-16 1 1.07945978078187e-07 7.15273898447334 -2.96755557059932 0.0232342408966049 13.5226470222681 8.11509838714867 1.66635650945193 0.0968107082774894 -11.9026463295117 12.4940770765861 -0.952663110412312 0.341619203803801 FBXO15 other 1 1 1 1.66635650945193 -0.952663110412312 0.0252084814131646 -25.1857929467398 31.2885053404876 -0.804953533978793 0.421560030828788 -128.43646287564 48.7902136754275 -2.63242263561402 0.00896970353081919 CBLN2 other 1 1 1 -0.804953533978793 -2.63242263561402 0.000746642508092108 158.459976664159 81.3607629706576 1.9476215669377 0.0524890247580611 -263.165224464332 139.007992007379 -1.89316614580234 0.0593971508218877 PMAIP1 other 1 1 1 1.9476215669377 -1.89316614580234 1.02704847366977e-06 416.026914350274 80.1691527681132 5.18936398833625 4.15162977226752e-07 151.29989542386 149.395663839868 1.01274623061371 0.3120880786451 P3H4 other 0.00913354207634523 1 0.00472496984381766 5.18936398833625 1.01274623061371 2.89816156164368e-11 264.985181934471 50.1468531883149 5.28418365434378 2.60497752407043e-07 -200.331893855219 93.4489409314116 -2.14375777679767 0.0329455877591925 NT5C3B other 3.37490913853406e-07 1 0.00300614406277727 5.28418365434378 -2.14375777679767 8.24167629442e-11 311.819366516378 66.1721959669731 4.71224147785587 3.93371971661581e-06 -342.705890466646 123.904626617002 -2.76588453412619 0.00607007882439119 RETREG3 other 9.41281849585708e-07 1 0.0417525010721603 4.71224147785587 -2.76588453412619 0.0331013868734729 111.606559644605 167.08189092727 0.667975200814476 0.504735180205873 -659.620216063405 332.465099312783 -1.9840284511874 0.0482921572838412 ERBB2 og 1 1 1 0.667975200814476 -1.9840284511874 0.000875306117931322 111.187144015173 44.1555810202265 2.51807679677551 0.01239407229789 -124.900712170301 87.9368303104333 -1.42034585200966 0.156691402539736 GRB7 other 1 1 1 2.51807679677551 -1.42034585200966 1.55053870162979e-05 179.654725629764 66.1047582774467 2.71772759346218 0.00700991078551267 -309.678698571357 131.53744492469 -2.35430069930777 0.019293306849198 MIEN1 other 0.124973419351361 1 1 2.71772759346218 -2.35430069930777 0.304732431832756 25.4837966694678 18.3011349849548 1.39247083256956 0.164947145581213 1.82192628925206 35.4643033988135 0.0513735253379604 0.959066583119486 STAC2 other 1 1 1 1.39247083256956 0.0513735253379604 0.0363891219566002 1314.33772512896 517.484389034873 2.53985966142909 0.0116636144035002 1716.40463899605 1143.51077101387 1.5009956027561 0.134551733037227 IGFBP4 other 1 1 1 2.53985966142909 1.5009956027561 0.000780657221576948 1193.19869933427 311.244870616901 3.83363329641158 0.000157166808338442 994.25149161057 580.006554354663 1.71420733808226 0.0876382387831677 FKBP10 other 1 1 1 3.83363329641158 1.71420733808226 1.47163587701348e-18 316.026882302033 52.7111024342697 5.99545195807878 6.96332967213248e-09 -281.481213039089 79.6002541908878 -3.53618485142113 0.000482684012488312 TXNL4A essential 2.10546944924318e-14 1 8.70068042532953e-05 5.99545195807878 -3.53618485142113 0.615000161591174 5.86948603909262 9.98108510234708 0.588060915111564 0.55698846645802 21.1714022216911 21.7466928891196 0.973545831986421 0.331163259027912 CACNA1A other 1 1 1 0.588060915111564 0.973545831986421 2.03398993121609e-06 140.565944137135 37.8850995835819 3.71032267783852 0.000251492785496769 -174.536773636319 95.2406547687523 -1.8325868722774 0.0679693294982629 SAMD1 other 0.0176692705324742 1 1 3.71032267783852 -1.8325868722774 8.40929961711956e-21 817.929194573027 109.167942839862 7.49239358456029 9.51357532109317e-13 -807.39143697839 246.544009309729 -3.27483697226679 0.00119421506253931 BRD4 og 1.24188536745622e-16 1 1.34084330575487e-08 7.49239358456029 -3.27483697226679 3.11318374656875e-13 59.0574671045116 24.4444587945718 2.415985872333 0.0163541685071181 -199.386569294495 41.0988662383332 -4.85138855505766 2.0708182359845e-06 SLC39A3 other 3.90362109982255e-09 0.0322550648436946 1 2.415985872333 -4.85138855505766 1.95225806564687e-06 5.76955807703798 144.998510459839 0.039790464458847 0.968289476038201 -1042.32166318304 243.359303785911 -4.28305656273571 2.5621633600283e-05 NFIC other 0.0169865974291934 0.390089371564309 1 0.039790464458847 -4.28305656273571 0.000154712668807137 3.24024526137957 6.77445466624556 0.478303482865482 0.632821269864801 -39.3068917463897 11.9169241429467 -3.29840915951909 0.00110287850144817 TPGS1 other 1 1 1 0.478303482865482 -3.29840915951909 7.0184073665331e-05 252.864328974495 114.526930603359 2.20790278445722 0.0280949410682601 -415.911708707358 201.435029792043 -2.06474369992517 0.0399056127843474 PLPP2 other 0.529187915436596 1 1 2.20790278445722 -2.06474369992517 1.42974138205638e-07 5.03644405234729 15.5165603526761 0.32458508444358 0.745745523690773 -107.366232114825 22.6256148867653 -4.74533985715582 3.37276307041806e-06 PRDM15 other 0.00135539483018944 0.0523722649574516 1 0.32458508444358 -4.74533985715582 3.56135553676894e-17 747.460650842655 229.696163910442 3.25412770556363 0.00128121291433451 -1931.77667695734 335.014302679544 -5.76625135555831 2.197019405864e-08 PFKL other 4.97058392266841e-13 0.000348579098934382 1 3.25412770556363 -5.76625135555831 5.76560544614108e-28 189.713485794049 46.2591377688634 4.1011029375853 5.4304846257392e-05 -634.604187016994 85.0272341406374 -7.46354028130965 1.13171431695508e-12 FEM1A other 8.96090398439247e-24 1.8064423927237e-08 0.52284705976617 4.1011029375853 -7.46354028130965 0.969913290288082 -6.96365423954585 28.4197698872905 -0.245028523002223 0.806618427599432 -8.26615499278493 53.07802128884 -0.155735929713773 0.876356266565395 VAV1 other 1 1 1 -0.245028523002223 -0.155735929713773 1.1601155880269e-12 123.886164080845 23.2633014910196 5.32539047085252 2.10690661928084e-07 -143.355224094621 52.5703420638089 -2.72692203373186 0.00680686892362144 MVB12A other 1.42578205768506e-08 1 0.00244380098770385 5.32539047085252 -2.72692203373186 3.44359434712838e-10 236.265364368619 111.609798780347 2.11688728902379 0.0351740024457332 -814.767214094892 199.85975488669 -4.07669475306233 5.99626448628999e-05 SH3GL1 other 3.81550253661825e-06 0.902317879896918 1 2.11688728902379 -4.07669475306233 4.66695524972659e-17 155.140726740078 36.6670328030374 4.23106847978237 3.18215994768595e-05 -320.774530399053 68.5961122556244 -4.67627857980759 4.60575268231919e-06 DUS3L other 6.49406822999456e-13 0.0713523205544889 0.313156360451774 4.23106847978237 -4.67627857980759 9.37490527522025e-11 217.59795656836 74.147795340008 2.93465173941525 0.0036231310110103 -492.762686450061 136.660103420595 -3.60575379438651 0.00036994209510257 DPP9 other 1.0681767070586e-06 1 1 2.93465173941525 -3.60575379438651 3.12314991279441e-37 363.920458230716 27.4715865310751 13.2471583983349 2.86489339481248e-31 -251.088205681409 83.3304277628317 -3.01316352768566 0.00282814673690716 CCDC97 other 4.94582020190122e-33 1 4.52624507446424e-27 13.2471583983349 -3.01316352768566 0.0457350668055615 7.99909815934268 14.295336444296 0.559559978914269 0.576238398008595 -92.6568590435092 43.3624938104428 -2.136797284966 0.0335034417359672 TMEM91 other 1 1 1 0.559559978914269 -2.136797284966 1.10109285371616e-09 41.1441736122031 6.65711429016811 6.18048178517363 2.35804464533871e-09 -26.9079634431333 26.8263971611425 -1.00304052316458 0.316742719169378 ZFP14 other 1.18609722202305e-05 1 3.00391307369698e-05 6.18048178517363 -1.00304052316458 3.44211560268851e-16 81.2582481945526 20.6175443844806 3.94121854083253 0.00010323316042655 -106.949405134231 32.9969412250021 -3.24119149120388 0.00133906986660008 SIRT3 other 4.6909151433439e-12 1 0.96677854739464 3.94121854083253 -3.24119149120388 0.911701990239306 -270.779748658943 773.710788962296 -0.349975407506096 0.726628991498709 -521.997773439226 1238.27013306958 -0.421554036957373 0.673684740762858 IFITM3 other 1 1 1 -0.349975407506096 -0.421554036957373 0.855427627928122 -62.2288568341634 272.079168863235 -0.228715991357074 0.819262162544383 -230.284091210645 435.443725795269 -0.528849257823309 0.597342893866411 PGGHG other 1 1 1 -0.228715991357074 -0.528849257823309 0.160735032482818 52.1829148991706 36.4180858627586 1.43288461386526 0.153065025403535 -20.5669084396307 52.2659991860239 -0.393504549036351 0.694262085970833 HUNK other 1 1 1 1.43288461386526 -0.393504549036351 0.304716904234901 -755.318763727125 1270.888715438 -0.594323290900268 0.552791728938343 -2951.86325181776 1930.58758550046 -1.52899732391709 0.127431472096163 COL6A1 other 1 1 1 -0.594323290900268 -1.52899732391709 3.19962467928122e-07 105.515161406039 69.745653386442 1.51285644743204 0.131503310720147 -394.608763820971 100.402378066511 -3.93027308137626 0.000108248308793863 IFNAR1 other 0.00296605207769369 1 1 1.51285644743204 -3.93027308137626 2.68983014120367e-10 1257.72813308612 249.680860043595 5.03734300204876 8.7420301072604e-07 -584.105376289897 357.892634622005 -1.63206872616088 0.103852709789594 SOD1 essential 2.99727772634325e-06 1 0.00973599893045591 5.03734300204876 -1.63206872616088 0.234686236010314 -943.0346083636 1515.92050014854 -0.622087113586229 0.534409547453002 -3874.92721702123 2300.54570887814 -1.68435132676014 0.0932693694609972 COL6A2 other 1 1 1 -0.622087113586229 -1.68435132676014 0.287280742286654 16.3251070813609 155.215474743078 0.105177058591504 0.916313118838137 -289.317001700935 225.230287637027 -1.28453861483846 0.200050504835402 SIK1 other 1 1 1 0.105177058591504 -1.28453861483846 0.0570604527036226 54.2298400881228 32.7603154649613 1.65535158372099 0.0990064786938415 -30.0809075600458 47.6553188778349 -0.631218262061339 0.528427891368422 TRPM2 other 1 1 1 1.65535158372099 -0.631218262061339 3.0200789191117e-13 354.947080351158 62.8313428213891 5.64920411394306 4.11127427045424e-08 -554.230682530759 149.104733159203 -3.71705626500128 0.000245380159855017 SCYL1 other 3.78868900402563e-09 1 0.000495490775075145 5.64920411394306 -3.71705626500128 1.02506080009441e-05 114.075051701966 89.1291997462058 1.27988416845202 0.201700986865713 -442.599560526669 128.305968546905 -3.44956330199767 0.000652735869311962 TMEM50B other 0.083870474663725 1 1 1.27988416845202 -3.44956330199767 5.23030507594831e-06 2780.48512251847 1547.82753632137 1.79637915547535 0.0738646660226633 -6529.53325467781 2248.01053330825 -2.90458303372303 0.00406894493655208 APP other 0.0438558883877297 1 1 1.79637915547535 -2.90458303372303 2.95354722169676e-09 154.107806102534 54.1320315358727 2.84688754015095 0.00475260177460629 -328.519385874949 86.1326851516294 -3.81410825979265 0.000169300978164691 DOPEY2 other 3.1080177413915e-05 1 1 2.84688754015095 -3.81410825979265 2.18935139407837e-12 222.495052978738 83.652039281536 2.65976842752055 0.0082887281096671 -592.676322507813 119.762332138034 -4.94877071886605 1.31876235654499e-06 URB1 essential 2.66444064659337e-08 0.0206017055339458 1 2.65976842752055 -4.94877071886605 4.60662646254294e-26 1435.71195824967 139.142456440593 10.3182881413528 3.4221951587464e-21 -497.165902135325 328.886491906636 -1.5116640980088 0.131815405820887 AKT1 og 7.09881137877867e-22 1 5.26744278834246e-17 10.3182881413528 -1.5116640980088 0.790947691559587 -1.92211615705231 9.34449982195053 -0.205694921469975 0.83718252665492 -17.8508358461363 26.6035809514593 -0.670993723691065 0.502791829073475 IL19 other 1 1 1 -0.205694921469975 -0.670993723691065 0.076377967609506 17.6101395463619 55.1175373352912 0.31950156697379 0.749591456203603 -219.726422572708 114.788525610825 -1.91418455288519 0.0566457973270436 EMP3 other 1 1 1 0.31950156697379 -1.91418455288519 3.25905048406528e-16 780.128745168851 108.583442965252 7.18460129707342 6.48217703559263e-12 -407.457281796395 223.189728738719 -1.82560946733079 0.0690055302414358 SAE1 essential 4.4433894299746e-12 1 8.95642401007833e-08 7.18460129707342 -1.82560946733079 0.091963434763899 1.52196021213206 1.85616565740156 0.819948481464015 0.412960777966035 -5.85830611371208 3.86483617741336 -1.51579674914783 0.130727749719594 NTN5 other 1 1 1 0.819948481464015 -1.51579674914783 0.00383697237278044 10.2736311453209 16.6387829667074 0.617450877619919 0.537452040569529 -95.7264499830881 34.6446288893643 -2.76309641788299 0.00611482724545081 LMTK3 other 1 1 1 0.617450877619919 -2.76309641788299 4.34499654704368e-20 101.793981095688 11.7386928876545 8.67166234519551 3.92465862501731e-16 -71.0238994309658 33.1580473451646 -2.14198075935021 0.0330831455687057 GEMIN7 other 6.35890244659842e-16 1 5.8253707971132e-12 8.67166234519551 -2.14198075935021 1.79897569478685e-07 90.6678788831883 37.3623502170454 2.4267177615027 0.0158885485104181 -434.992115581858 106.881108552536 -4.06986904863587 6.17610769115632e-05 CBLC other 0.00169445520691973 0.928886596749911 1 2.4267177615027 -4.06986904863587 0.000879053996975447 48.4051926134094 13.3053514988294 3.63802434063226 0.000329713250926593 -10.7698945956738 48.7734901718483 -0.220814515379712 0.825405622108368 WTIP other 1 1 1 3.63802434063226 -0.220814515379712 0.740555953284787 -1.63076177001149 7.70470910302233 -0.211657798913108 0.832532518760038 9.99565390364678 17.8080321152727 0.561300307577175 0.575054973197205 ADAMTS10 other 1 1 1 -0.211657798913108 0.561300307577175 0.481651299858835 20.5631548964227 17.5281046125323 1.17315336432442 0.241779819800698 -16.2596045772823 103.687667583988 -0.15681329280661 0.875510506157221 SLC6A3 other 1 1 1 1.17315336432442 -0.15681329280661 1.12857613054669e-10 30.0031226580067 21.6661747770324 1.38479094564547 0.167247059959918 -180.855347126019 34.8040952788541 -5.19638122114616 3.98365667927021e-07 CAPN10 other 1.28036962010522e-06 0.00626549522515618 1 1.38479094564547 -5.19638122114616 0.142798441899138 -69.8327241329684 39.2995929108957 -1.77693250643335 0.0766968838916057 -4.96554283247314 90.9965465172494 -0.0545684756457419 0.956522312801615 MYO1F other 1 1 1 -1.77693250643335 -0.0545684756457419 6.09609383378547e-18 242.395046985415 29.6245669922362 8.18223088455402 1.14551060564816e-14 -114.127797540317 71.2659781089751 -1.60143452133359 0.110463147650502 ERVK3-1 other 8.62902082172333e-14 1 1.66809254394485e-10 8.18223088455402 -1.60143452133359 0.786795242432112 -1.25702216914073 1.81934155797456 -0.69092148400114 0.490206265797458 -1.37735772848379 4.62525274514871 -0.297790802876331 0.766091000142075 NLRP12 other 1 1 1 -0.69092148400114 -0.297790802876331 7.78071489535429e-89 314.340316769348 10.6425280014451 29.5362452160486 5.38474169724785e-87 -150.090400675073 64.936196099845 -2.31135190679011 0.021558347391474 ZNF787 other 1.24273578308599e-84 1 8.60050943884426e-83 29.5362452160486 -2.31135190679011 1.22062985285435e-22 91.3335509172833 13.5375715830715 6.74667168751997 9.2432846190174e-11 -114.673257954073 25.9185542608844 -4.42436938418032 1.4062034096994e-05 TIMM29 other 1.8370479285458e-18 0.215683478979694 1.23684391487072e-06 6.74667168751997 -4.42436938418032 0.0309419451880255 14.9225539276008 19.4701898171549 0.76643083954183 0.444082207315783 116.41099149135 44.7563679119402 2.60099281783528 0.00980218571874712 FBN3 other 1 1 1 0.76643083954183 2.60099281783528 1.66526328193269e-21 526.606158206136 86.2042351692969 6.10882002690392 3.51813707944941e-09 -797.746242725895 165.430347739635 -4.82224847874611 2.38271264956536e-06 CARM1 other 2.47774523718766e-17 0.0371012186663823 4.45501698370679e-05 6.10882002690392 -4.82224847874611 4.51738281398889e-17 126.488357259065 20.6487579218168 6.12571263307908 3.13816965703671e-09 -153.931510759095 47.0911862060677 -3.26879662970268 0.00121847860378397 EVI5L other 6.28774513879113e-13 1 3.98108202691678e-05 6.12571263307908 -3.26879662970268 1.47354909549419e-05 166.332946652344 36.0825116519039 4.60979402589808 6.2344129244327e-06 137.648797708557 94.160838339607 1.46184762302246 0.144950179920469 SLC47A1 other 0.119033295934021 1 0.0650685676923041 4.60979402589808 1.46184762302246 3.28115075914904e-22 806.842538297104 77.3680881592712 10.4286218968747 1.25065581467255e-21 -29.8178573807595 230.542175650708 -0.129337971660058 0.897186168018498 PSMB6 essential 4.92172613872355e-18 1 1.92901152855094e-17 10.4286218968747 -0.129337971660058 0.320643298469762 6.95165281326703 24.7305731085475 0.281095500001347 0.778851649240678 -68.5221991051679 54.2939272785749 -1.26206009658483 0.208012238017908 SIGLEC10 other 1 1 1 0.281095500001347 -1.26206009658483 2.27196860134662e-13 88.3336753574433 14.2034753468763 6.21915926913407 1.87638068782408e-09 -68.3325052985702 29.3422396133033 -2.32881014534383 0.02060198762373 ZNF473 other 2.86404361885755e-09 1 2.40045381393334e-05 6.21915926913407 -2.32881014534383 0.3924791671831 10.1430306425092 19.0781181680459 0.531657816204214 0.595398544890707 -39.6644140597776 40.8925959826036 -0.969965665096233 0.332928501630484 FAM71E1 other 1 1 1 0.531657816204214 -0.969965665096233 1.00713092678516e-09 4502.00510606686 911.866020014638 4.93713441147263 1.38210872743728e-06 -4034.56952629504 1893.71375050877 -2.13050653786039 0.0340237388163947 RPS11 essential 1.08770140092797e-05 1 0.0151769359359888 4.93713441147263 -2.13050653786039 2.99628356867052e-08 2848.31020943921 679.051773225634 4.19454056633878 3.69993990357712e-05 -3280.49935011361 1410.21778642887 -2.32623597694148 0.0207383047816641 RPL13A other 0.000296841813148189 1 0.362002120165986 4.19454056633878 -2.32623597694148 3.59082706023823e-13 25.0942113303535 4.10002050469229 6.12050873931834 3.25691474829234e-09 -21.8510753971086 9.10955672800991 -2.39869798822606 0.0171296050486749 CTU1 other 4.49535639671225e-09 1 4.1287908264102e-05 6.12050873931834 -2.39869798822606 3.27388591813774e-09 165.131755001175 42.2172370363136 3.91147707887977 0.000115842030426789 -275.699357298935 87.6744615210813 -3.14457998960899 0.00184690878776796 NOSIP other 3.43120366807301e-05 1 1 3.91147707887977 -3.14457998960899 0.243257041461893 13.2404785230222 10.6295708216383 1.24562682211675 0.213977292619891 35.6639746800925 23.3363433455176 1.52825891152063 0.127614594023774 IGLON5 other 1 1 1 1.24562682211675 1.52825891152063 0.13907340879719 -6.39580390239728 88.2500430466766 -0.0724736632594554 0.94227803189149 -339.294766137133 183.272889144174 -1.85130909280435 0.0652049672096549 RCN3 other 1 1 1 -0.0724736632594554 -1.85130909280435 2.32917436620284e-05 55.1426584133921 16.2417466141442 3.39511874698074 0.000787894195762697 -69.0093961914189 38.8306519186746 -1.77718870998997 0.0766505395184471 ZNF614 other 0.184587068521575 1 1 3.39511874698074 -1.77718870998997 0.592285297221306 -3.21935529922099 19.6836045602105 -0.163555170465514 0.870202351752575 -29.7671346737152 31.4839867931396 -0.945469036983637 0.345255519410244 SLC2A5 other 1 1 1 -0.163555170465514 -0.945469036983637 1.04069227456175e-07 590.415057140028 163.71820640532 3.60628832982892 0.000369443795282565 -528.566816805363 262.002827583019 -2.01740882600925 0.0446349461626523 RERE other 0.000996150645210503 1 1 3.60628832982892 -2.01740882600925 1.33005571511293e-07 31.2907266670473 16.0830358719304 1.94557339274849 0.052751453645274 -92.4639226135781 25.6164988275516 -3.60954567741824 0.000365967239666075 MMEL1 other 0.00126302090707123 1 1 1.94557339274849 -3.60954567741824 0.662643142670444 6.88937216494559 15.5583294580163 0.442809247839645 0.65825958082547 -10.8599799859682 24.8480132414855 -0.437056270069783 0.662421184630486 CFAP74 other 1 1 1 0.442809247839645 -0.437056270069783 0.0268271849959129 42.8033765283332 22.7281718836835 1.88327405949713 0.0607380422660123 94.8120071164498 35.7409086533825 2.65275872071252 0.00845647404741642 PRDM16 og 1 1 1 1.88327405949713 2.65275872071252 0.0172848605601691 -357.680040637745 300.265293473019 -1.19121339832732 0.234604446108422 -1267.69703331855 449.726205398408 -2.81881957978301 0.00517281047101279 PADI3 other 1 1 1 -1.19121339832732 -2.81881957978301 0.0110307275230786 61.5008274159714 23.2782855494179 2.64198268748831 0.00871779313837851 6.3298567103712 36.0862360367193 0.175409169965255 0.860888166245315 FHAD1 other 1 1 1 2.64198268748831 0.175409169965255 0.0258797682477161 -244.083652322882 116.882150946666 -2.08828850552433 0.0376984145412714 -460.777022372778 175.061744952456 -2.63208288308744 0.00896932868184969 PADI1 other 1 1 1 -2.08828850552433 -2.63208288308744 0.000285931730155736 80.4353804187567 226.768569355797 0.354702508585106 0.72308631805535 -1141.21999410204 352.228116005195 -3.24000255018031 0.00134332436258755 EPHA2 other 1 1 1 0.354702508585106 -3.24000255018031 4.48903774119279e-08 451.249603730465 123.434630961773 3.65577796291393 0.000307508312920133 -386.604172810381 191.724751084207 -2.01645416475508 0.0447316509573503 ARHGEF19 other 0.000439476794862774 1 1 3.65577796291393 -2.01645416475508 6.96908928260759e-08 -311.398382803026 303.658091721413 -1.02549015255195 0.306039758296793 -2572.75724104278 470.733875527732 -5.46541766971519 1.04143500222295e-07 EFHD2 other 0.000673910933628154 0.00164546730351226 1 -1.02549015255195 -5.46541766971519 1.55978874263948e-25 140.388060528649 23.112321687972 6.07416521905323 4.18487611181261e-09 -198.600232761897 37.0278081065031 -5.36354277819154 1.7457839802058e-07 PEX14 other 2.3969273608141e-21 0.00275397422877465 5.28089516549634e-05 6.07416521905323 -5.36354277819154 0.097407289707153 2086.95114375291 1361.16393266486 1.53321072772411 0.126386216843331 4615.84814793313 2180.69467795773 2.11668703307699 0.0351944974645376 PGD essential 1 1 1 1.53321072772411 2.11668703307699 0.237535390387007 -17.7971557913028 20.3881640899399 -0.872916056236983 0.383478782729458 -51.5929201805558 30.463035241739 -1.69362375650164 0.0914815864899787 MYOM3 other 1 1 1 -0.872916056236983 -1.69362375650164 5.30311983537014e-07 -127.727284075624 408.530051844838 -0.312650889448239 0.754786364076471 -2751.07589774887 587.947841004397 -4.6791155709479 4.5544661716948e-06 SH3BGRL3 other 0.00483379372993988 0.0705623443980675 1 -0.312650889448239 -4.6791155709479 3.66430408401048e-08 37.1894530979095 44.7424586701548 0.831189304371342 0.406598428472974 -283.437681179522 64.3924035883098 -4.40172544251756 1.54627042950632e-05 CNKSR1 other 0.000360494235784951 0.236935017913253 1 0.831189304371342 -4.40172544251756 6.59510870605468e-10 2588.88587972267 779.266551354743 3.32220839611546 0.00101543094048391 -3242.6348486681 1152.42659531875 -2.81374524142357 0.00525411714538134 RPL11 essential 7.20185870701171e-06 1 1 3.32220839611546 -2.81374524142357 0.173531770218073 21.92820888015 19.3787693357263 1.13155838228198 0.258816783341957 -15.9552301692546 28.954845105796 -0.551038353372533 0.582059714319325 IL22RA1 other 1 1 1 1.13155838228198 -0.551038353372533 1.67450154065998e-06 52.7164838111613 40.2958588063548 1.30823576845687 0.191901865429548 -198.489604283119 57.992950774678 -3.42265053996507 0.000715961553592485 ZNF593 other 0.0146502139792342 1 1 1.30823576845687 -3.42265053996507 0.00065573725930267 43.809226111901 21.964158601139 1.99457793523806 0.0470905237009381 -56.6077011141801 31.4467352062801 -1.80011377152039 0.0729547020927314 C1orf216 other 1 1 1 1.99457793523806 -1.80011377152039 0.000100695046172521 218.992013569406 109.296487615292 2.00365097129404 0.0460991370686518 -354.109811068944 156.312423037077 -2.26539774759264 0.0242748158247474 KIAA0319L other 0.746150292138384 1 1 2.00365097129404 -2.26539774759264 0.0535771200017744 22.6509555195303 22.7748982042565 0.994557925852641 0.320835252518772 -45.0570022127822 32.5047260274663 -1.38616772757012 0.16683095376384 EVA1B other 1 1 1 0.994557925852641 -1.38616772757012 0.00166904640627339 32.7498662170102 26.5764565767062 1.2322886658154 0.218925314953554 -90.0960496340355 42.3295587582353 -2.12844291972467 0.0342161085262088 DMRTA2 other 1 1 1 1.2322886658154 -2.12844291972467 5.09807883438498e-11 149.445769511776 26.6655027581921 5.60446097217738 5.10425263605505e-08 -10.9334938425219 38.4050531455904 -0.284688939267287 0.776098299999915 PLK4 essential 5.87859470392932e-07 1 0.000612969699063851 5.60446097217738 -0.284688939267287 3.91577333067196e-06 48.4056886732034 113.294752775655 0.427254462252597 0.669534520209793 -649.090024201652 164.804720725462 -3.93854023928679 0.000104418521836829 MAP3K6 other 0.0331979262974369 1 1 0.427254462252597 -3.93854023928679 0.929508180977516 99.7003336366382 263.015600382415 0.379066235963485 0.704936606316923 98.5231360815932 382.596823820228 0.257511641361369 0.796979978629812 FCN3 other 1 1 1 0.379066235963485 0.257511641361369 1.06317527991359e-20 106.959772013305 23.0232057480349 4.64573757381439 5.29234167288434e-06 -164.964733669038 33.1864090884587 -4.97085217111991 1.18358051238768e-06 GPN2 essential 1.56786458528857e-16 0.0185064648916938 0.0555748799069584 4.64573757381439 -4.97085217111991 0.00167868616818355 23.4932093148654 137.557278012569 0.170788559168195 0.864517940384202 -574.664104273301 200.098311980142 -2.87190880615891 0.004403633529954 SYTL1 other 1 1 1 0.170788559168195 -2.87190880615891 4.61778654404202e-09 230.00772435253 104.465863594384 2.20175008791 0.0285257011123628 -560.781961747139 152.099925491747 -3.68693120614031 0.000274158633422139 WDTC1 other 4.79649488329645e-05 1 1 2.20175008791 -3.68693120614031 4.3842544450651e-06 61.4174161419215 20.0756002987516 3.05930658251553 0.00243912544325152 -42.1360067239277 29.5303927512389 -1.42686916082957 0.154760293912795 NBPF3 other 0.03703818155191 1 1 3.05930658251553 -1.42686916082957 0.000225145355946107 807.595598095771 1222.29942469848 0.660718300096548 0.509354240462292 -5235.46083143517 1815.77552166083 -2.88331942411387 0.00425066618616353 HSPG2 other 1 1 1 0.660718300096548 -2.88331942411387 3.94418240886422e-40 134.166667713314 9.85337797182426 13.6163118980073 1.42407162083599e-32 -108.5168550004 30.4325704689436 -3.56581298681756 0.000428151387508133 ITGB3BP other 6.25783980990397e-36 1 2.25259648983837e-28 13.6163118980073 -3.56581298681756 4.58774577613544e-25 1628.17712390378 235.287079162716 6.91995977721239 3.25800339479103e-11 -1444.49394589725 363.185061999938 -3.97729448987495 8.95012576020876e-05 SERBP1 essential 7.02842652903949e-21 1 4.41654940197871e-07 6.91995977721239 -3.97729448987495 8.45909375835502e-15 168.496721584209 31.420434657449 5.36264769794528 1.74906117253566e-07 -156.367363615457 53.9351281003007 -2.89917478873263 0.00404543142940129 BCL10 other 1.11144032891027e-10 1 0.00203835589047306 5.36264769794528 -2.89917478873263 0.907239153612794 82.3332411788596 385.3113623574 0.213679764528954 0.830956288425316 -144.566794051877 661.410891154584 -0.218573349766762 0.82714572039677 CYR61 other 1 1 1 0.213679764528954 -0.218573349766762 0.147964433308925 142.124792655453 82.8641264629376 1.71515466006898 0.0874557456511883 18.3812556346466 128.714017988282 0.142806944588739 0.886548381883861 PRKACB other 1 1 1 1.71515466006898 0.142806944588739 4.03478268199464e-16 225.407028270258 32.7150410206855 6.89001209345068 3.9490412034063e-11 -77.6063345172708 55.189302607105 -1.40618436637537 0.160823468896197 PIGK other 5.48932183885371e-12 1 5.34107822760701e-07 6.89001209345068 -1.40618436637537 0.104634342954889 -35.6220185765768 414.685685329763 -0.0859012496374207 0.931609298496207 -1074.80794150421 592.758551584625 -1.81323059554504 0.070919045373212 TINAGL1 other 1 1 1 -0.0859012496374207 -1.81323059554504 0.018156446207393 6.43747224004328 21.42392307189 0.300480552438586 0.764041862406908 -69.3784437033955 30.8250082831539 -2.25071938557471 0.0252081329171402 AZIN2 other 1 1 1 0.300480552438586 -2.25071938557471 5.71962151083325e-08 1994.93946773397 997.424735341089 2.00009022941642 0.0464883254800102 -6571.30613959855 1738.86009248377 -3.77908847756242 0.000193582613463288 RPS8 essential 0.000555890014637883 1 1 2.00009022941642 -3.77908847756242 3.65248627915098e-15 363.053239597681 64.6931368961967 5.61192820469067 4.9409932817696e-08 -314.035467075569 112.78275946096 -2.78442794427522 0.00574005614434457 KIF2C other 4.85159752459625e-11 1 0.000594055622267159 5.61192820469067 -2.78442794427522 1.82651801850156e-10 4523.52236080269 1038.06478460048 4.35764937594298 1.86997202305854e-05 -5617.77090460196 1985.27109264917 -2.82972482972365 0.00500857624403051 PTPRF other 2.0513623865791e-06 1 0.18783868971623 4.35764937594298 -2.82972482972365 0.00305085545297319 5.56625516542351 2.54546792565214 2.18673160613386 0.0296172373306735 -5.10148053815699 4.43764069185664 -1.14959296896627 0.251325075550946 BEST4 other 1 1 1 2.18673160613386 -1.14959296896627 0.0525579626521318 -18.1279975959133 45.9063840598927 -0.394890557536882 0.693233139516442 -181.92467108979 80.7656685841031 -2.25250003224263 0.0250880687578026 MOB3C other 1 1 1 -0.394890557536882 -2.25250003224263 0.941479043055985 -49.5148014587548 376.762549170607 -0.131421771000741 0.89553882155441 -224.865120349769 656.66303764381 -0.342436085875358 0.732287197268677 CYP4B1 other 1 1 1 -0.131421771000741 -0.342436085875358 0.911605121428209 -1.51656639609185 11.2277121796794 -0.135073501335083 0.892654030212143 -8.30480589829436 19.8787988344576 -0.417772017688461 0.676444625600254 TMEM61 other 1 1 1 -0.135073501335083 -0.417772017688461 0.000236555142622378 553.433761268303 242.402344462859 2.28312049743026 0.0231920121552503 -808.728927402874 439.149386788365 -1.84158045469984 0.0666212676139274 LMO4 other 1 1 1 2.28312049743026 -1.84158045469984 0.358670674830874 -3.17513945900433 5.71226534471398 -0.555845932812371 0.578771430699194 -11.7300178928534 8.50499899447678 -1.37919097938412 0.168964687928639 SYPL2 other 1 1 1 -0.555845932812371 -1.37919097938412 3.68746002681e-22 185.216249170388 24.9686868557683 7.4179411292348 1.52040626296617e-12 -111.246820456048 40.3288552775914 -2.75849189594681 0.00620069119178172 MTF2 other 5.52713383418551e-18 1 2.13312998694154e-08 7.4179411292348 -2.75849189594681 0.0817858476695409 -4.3344989348196 38.0069516951167 -0.114044898143634 0.909286028183847 -120.433766937086 61.4747805571856 -1.95907599580701 0.0511215973487126 SLC44A3 other 1 1 1 -0.114044898143634 -1.95907599580701 0.0428926613524696 94.7738612191376 301.637308617745 0.314198073353192 0.753612345284501 -941.249794939477 513.561781853018 -1.83278785182046 0.0679311657479531 IGSF3 other 1 1 1 0.314198073353192 -1.83278785182046 8.87700557828607e-10 77.129039573648 18.2154448403122 4.23426604454675 3.22413454885585e-05 -62.3588161923122 32.3315552028447 -1.92872924921427 0.0548966433141457 ZNF697 other 9.61557244239947e-06 1 0.317061391534485 4.23426604454675 -1.92872924921427 1.34244063845828e-13 99.1732176488337 51.7278311343997 1.91721198190508 0.0562545878193806 -373.849394501394 76.2844922279996 -4.90072600056155 1.63952799595096e-06 CTTNBP2NL other 1.70449687865047e-09 0.0255717181528471 1 1.91721198190508 -4.90072600056155 7.67631564736509e-21 155.337888251884 30.7250111190218 5.05574717776796 7.86999410094726e-07 -182.632210392127 45.6420863209409 -4.00139925918186 8.11664340397625e-05 STRIP1 essential 1.13448268952409e-16 1 0.00878842241252781 5.05574717776796 -4.00139925918186 6.74085038903723e-18 360.972318703295 113.393919450685 3.18334810589452 0.00162429820511581 -852.012356594044 168.832348063157 -5.04649947932563 8.22624570735554e-07 PSMA5 essential 9.53358470521536e-14 0.0128938175217091 1 3.18334810589452 -5.04649947932563 0.753213935875824 11.3829652681755 52.2822620595542 0.217721361313886 0.827808860730282 53.5804273815927 76.8286756460393 0.697401418559463 0.486145101875514 C1orf162 other 1 1 1 0.217721361313886 0.697401418559463 0.284097202796357 -204.515537921482 156.256771841677 -1.30884271773323 0.191688313474697 -28.0193292874454 229.6190020938 -0.122025307278356 0.902968749852602 CD53 other 1 1 1 -1.30884271773323 -0.122025307278356 5.55555670178339e-07 329.09023267322 310.269208292791 1.06066030362468 0.289785202613409 -1642.00087661162 462.59289226038 -3.54955924330844 0.000454480766976695 CELSR2 other 0.00505222326460182 1 1 1.06066030362468 -3.54955924330844 0.50780896891029 -5.3153199362394 5.27238739590254 -1.00814290322639 0.314352885487898 9.98080589741679 17.8524885949676 0.559070845743614 0.576609861480484 ITGA10 other 1 1 1 -1.00814290322639 0.559070845743614 6.30822161767386e-07 280.919612066694 51.829337850252 5.42008877054038 1.31736041356338e-07 -95.4793313358243 174.735448507724 -0.546422217994329 0.585225326130032 GPR161 other 0.00570767891967131 1 0.00154763501385426 5.42008877054038 -0.546422217994329 0.0035572877909722 312.366765364409 92.1580604238038 3.38946765945312 0.000804432624044072 109.173628678605 307.902008409032 0.354572642259524 0.723185530227609 ALDH9A1 other 1 1 1 3.38946765945312 0.354572642259524 0.0667133863430521 911.594157817813 424.999877240024 2.1449280497156 0.0328443651665277 -1167.87279640958 1456.17865226594 -0.802012029631307 0.423246127393111 ATP1B1 other 1 1 1 2.1449280497156 -0.802012029631307 1.1766001008519e-12 347.120650650181 45.5156427648441 7.62640335419572 4.09862691513595e-13 -186.918428221415 153.449698230974 -1.21810880292553 0.224242076857077 TIPRL essential 1.44580620392681e-08 1 5.82701788524878e-09 7.62640335419572 -1.21810880292553 0.00862644463406831 78.4902263362573 29.0535371847713 2.70157212999864 0.00733480919757986 -136.567851553871 99.423739583973 -1.37359399400307 0.170698803641983 NME7 other 1 1 1 2.70157212999864 -1.37359399400307 3.16276180464369e-15 643.219898816928 74.4744548677261 8.63678559258136 5.12995818722696e-16 -145.329852614904 249.416508326344 -0.582679364690448 0.560595460649951 POGK other 4.20710575253704e-11 1 7.60465001674525e-12 8.63678559258136 -0.582679364690448 2.48819332746556e-08 375.803276151675 62.6849858857353 5.99510825186599 6.469283062879e-09 -181.053248603676 211.333765349099 -0.856717090639052 0.392358181139047 MPC2 other 0.000247525472216274 1 8.0943669682742e-05 5.99510825186599 -0.856717090639052 2.29605869943517e-10 2372.94748430415 342.106119435611 6.93629066974574 2.95377085567086e-11 841.764235263344 1146.9257334325 0.733930899557135 0.463625342796045 CREG1 other 2.56768244357835e-06 1 4.00885780531649e-07 6.93629066974574 0.733930899557135 1.25072575165635e-07 423.84551897075 73.8903010744494 5.73614551311271 2.58367291620358e-08 -144.517060115961 249.110936665225 -0.580131334459129 0.562308083346304 DCAF6 other 0.00119031569785135 1 0.000314407157172813 5.73614551311271 -0.580131334459129 0.839272347180832 -1.46080717061889 8.30646024081683 -0.17586398155988 0.860532142035398 15.4208950062316 27.8134012089689 0.554441180723301 0.579734208768934 GPA33 other 1 1 1 -0.17586398155988 0.554441180723301 0.636083251747031 -9.99288512434273 10.8737825644958 -0.918988867495908 0.358915619457267 -10.8992763676923 36.322985511794 -0.300065542909552 0.764356355376496 RXRG other 1 1 1 -0.918988867495908 -0.300065542909552 0.146957888358692 13.8705964634869 7.86392151870691 1.7638269189858 0.0788837134666022 -20.2605023490596 26.5644498389188 -0.762692337764006 0.446307817084135 TBX19 other 1 1 1 1.7638269189858 -0.762692337764006 2.5998275316867e-10 518.003414584176 78.516512907206 6.59738181694816 2.18822475853897e-10 -452.905762354697 262.325312688092 -1.72650423138238 0.0853963587501346 TMCO1 other 2.89958764609018e-06 1 2.89261430831267e-06 6.59738181694816 -1.72650423138238 0.0232558676065257 10.1391874838454 4.34015457393846 2.33613511019371 0.020210844572204 -19.5672636876435 14.6611100070465 -1.33463725995092 0.183111213361017 XCL1 other 1 1 1 2.33613511019371 -1.33463725995092 0.201955684657761 2.50351883808973 1.42977078175511 1.75099314522048 0.0810743563939268 -1.38983271502639 4.82978805456476 -0.287762671844952 0.77374754284256 XCL2 other 1 1 1 1.75099314522048 -0.287762671844952 9.58446214510419e-06 133.774752451265 27.37427774596 4.88687788195648 1.75567383858399e-06 -20.0528790256946 91.7734638385487 -0.218504109869628 0.827200812484244 POU2F1 other 0.0786884342113054 1 0.0191333334928883 4.88687788195648 -0.218504109869628 0.645205533208699 -10.1331279755747 15.0699894651688 -0.672404449850172 0.501899142017795 -34.8130311834882 50.4604429634224 -0.689907363847824 0.490842812263979 MAEL other 1 1 1 -0.672404449850172 -0.689907363847824 0.00473573481927856 35.5456464446588 10.8668110646023 3.2710282927846 0.00121031980074323 -10.2095338845159 36.3864952385693 -0.280585800242006 0.779242190054027 ILDR2 other 1 1 1 3.2710282927846 -0.280585800242006 0.863470554199924 -16.190372656642 44.8138889576205 -0.361280242202432 0.718170421340173 57.8748384546381 151.38201754299 0.382309863443342 0.702530083339543 DPT other 1 1 1 -0.361280242202432 0.382309863443342 0.000261967142405396 270.438969185817 65.718554376824 4.11510830921729 5.13945858215851e-05 -8.32793471315062 219.567065423349 -0.0379288883653541 0.969772304913053 MGST3 other 1 1 0.495803569420832 4.11510830921729 -0.0379288883653541 0.000440111013022295 30.8529262681422 8.03721028071987 3.83876061351213 0.000153967534513559 -23.3409723533081 27.0963435267126 -0.861406718227413 0.389775605621853 ADCY10 other 1 1 1 3.83876061351213 -0.861406718227413 2.13082736764072e-16 395.592801313814 44.2556305595331 8.93881289933624 6.55314342287448e-17 -107.477173646991 141.389635394428 -0.760148884655987 0.44783378773707 RFWD2 other 2.91710266630015e-12 1 9.80284724627794e-13 8.93881289933624 -0.760148884655987 0.0351558828698617 363.196949626068 151.156842997515 2.4027820535524 0.0169460562280513 -439.64132258892 512.975611905567 -0.857041372699514 0.392182066358137 NECTIN4 other 1 1 1 2.4027820535524 -0.857041372699514 1.51773924285947e-09 398.526383871103 60.7916571719374 6.55560980586445 2.78767942474419e-10 -105.715855942855 212.046876966152 -0.498549459701449 0.618501211579694 UFC1 other 1.62443631163249e-05 1 3.66997996267573e-06 6.55560980586445 -0.498549459701449 8.06015043303615e-13 124.849096077053 15.9349726139196 7.83491124220656 1.06045901489611e-13 -8.32615987980998 55.5718112248301 -0.149827038138533 0.881012112943691 PPOX other 9.97121210070902e-09 1 1.5210163650655e-09 7.83491124220656 -0.149827038138533 1.65337492083844e-15 255.221563276399 29.5249491335898 8.64426767076255 4.67236261334106e-16 -93.5822777540016 97.9352399633529 -0.955552646718584 0.340143664857787 NUF2 essential 2.21486104395517e-11 1 6.93004822810746e-12 8.64426767076255 -0.955552646718584 0.682763037852991 -52.7086211975521 74.8367361875614 -0.704314804235313 0.481837108637657 115.087123506951 248.2359472811 0.463619893764327 0.64328952015725 RGS5 other 1 1 1 -0.704314804235313 0.463619893764327 5.75777830440151e-19 536.514720587965 54.3524259251154 9.8710354037767 7.51232747106194e-20 -59.1811132310451 190.839830758725 -0.310108812168602 0.756714809101478 SDHC ts 8.29523120315126e-15 1 1.1495363496219e-15 9.8710354037767 -0.310108812168602 2.09456216288442e-11 422.011511598074 59.1167041817292 7.13861703624036 8.72255848860987e-12 -259.805737743863 200.622260296621 -1.29499955468421 0.196426632227202 PFDN2 essential 2.45336066138652e-07 1 1.20231746206998e-07 7.13861703624036 -1.29499955468421 9.9096288255368e-05 20.2313804916825 5.46146289992966 3.70438852417052 0.000256452846813408 -39.6326737194146 19.1760466580392 -2.06678020898533 0.0396976376482649 NR1I3 other 0.734997169990064 1 1 3.70438852417052 -2.06678020898533 3.37776255153958e-15 239.11061636625 27.7780553847507 8.60789616315311 6.08104219672755e-16 -62.4286050752434 96.8735176040276 -0.644434171683757 0.51983702008637 USP21 other 4.49039753601672e-11 1 9.00115865959612e-12 8.60789616315311 -0.644434171683757 1.50604806457378e-13 426.747721688361 54.1109956037931 7.88652503851633 7.58003514667898e-14 -254.48283461737 176.381720684843 -1.4427959633758 0.150228526771731 PRCC other 1.90921713146019e-09 1 1.08925105057777e-09 7.88652503851633 -1.4427959633758 0.0570596277669231 -65.5908694148456 27.3776731371482 -2.39577954949892 0.0172636620432834 -35.3079760865628 89.1949618266507 -0.395851686726246 0.692525908480393 FCRL5 other 1 1 1 -2.39577954949892 -0.395851686726246 8.33729184292075e-09 128.329866239329 20.3424827512481 6.30846626778904 1.13729117050568e-09 43.8642636271139 66.3089279845993 0.661513689940844 0.508842919121678 RRNAD1 other 8.53738684715085e-05 1 1.46699188083528e-05 6.30846626778904 0.661513689940844 4.18744981237708e-13 437.463156723232 55.5063975992178 7.88131054517212 7.84204990461121e-14 -117.372124829678 180.930212211449 -0.648714901702034 0.517069986313696 MRPL24 other 5.2292873256965e-09 1 1.12674573029454e-09 7.88131054517212 -0.648714901702034 1.15124628315384e-16 160.609976792224 17.5599751419245 9.14636697911763 1.40430701421958e-17 -9.56974044708591 65.6486798347986 -0.145772016606696 0.884208941183714 PIGM other 1.58595687967273e-12 1 2.11404377920615e-13 9.14636697911763 -0.145772016606696 3.97118677311346e-12 350.972274309179 47.5358812938859 7.3833126631087 1.88897649458234e-12 -214.087617553018 154.949293453737 -1.38166243150336 0.168209157210669 ISG20L2 essential 4.78091175615129e-08 1 2.64475599006474e-08 7.3833126631087 -1.38166243150336 0.996591408618211 9.09266605983112 303.726938240856 0.0299369759972381 0.976139270434429 77.9509254915131 990.036856418624 0.0787353773610956 0.937300997615219 CRABP2 other 1 1 1 0.0299369759972381 0.0787353773610956 7.92473403167114e-07 1914.08193753614 364.931741716542 5.24504097268386 3.14475124441946e-07 -1327.91289602751 1189.54175243392 -1.11632306584486 0.265269055776712 HDGF other 0.00711324126682801 1 0.00360828757784689 5.24504097268386 -1.11632306584486 0.000296265733540059 148.431556538799 36.9097406719688 4.02147383960151 7.53247109061282e-05 -39.520973410694 114.739485430542 -0.344440915543569 0.730785858991366 ABL2 other 1 1 0.716112026584561 4.02147383960151 -0.344440915543569 0.00306675774609102 391.653071465961 122.764048544679 3.19029126286449 0.00159034768276348 -395.004045964142 380.324077350719 -1.03859857812758 0.299927590286212 XPR1 other 1 1 1 3.19029126286449 -1.03859857812758 0.815963857993114 8.94844480962555 55.9007108129374 0.160077478076622 0.872939292785097 -105.232791117141 174.332834188859 -0.603631505257002 0.546593576349849 RGS16 other 1 1 1 0.160077478076622 -0.603631505257002 8.34413019058591e-08 236.353068758729 41.5744381846232 5.68505743142302 3.3996599402274e-08 -121.875862535685 125.846191686141 -0.968450939219852 0.333689129432869 TOR1AIP1 other 0.000802955648240082 1 0.000411290859568711 5.68505743142302 -0.968450939219852 0.662082769477627 -5.27239105271286 8.85191075651313 -0.595621803895108 0.551928692212764 -19.8579305122154 26.7948120647072 -0.741111020456506 0.459272591432947 FAM163A other 1 1 1 -0.595621803895108 -0.741111020456506 0.208595395370953 -117.435463742045 72.7163572524757 -1.61498001521585 0.107509489030819 -176.76592129349 224.978585674572 -0.78570109578864 0.432747214713572 HMCN1 other 1 1 1 -1.61498001521585 -0.78570109578864 0.893045317988352 -2.87464566206384 40.4336862366355 -0.0710953150608175 0.943374141565931 -59.0374153150193 124.590565015907 -0.473851413287049 0.635985992581997 RGL1 other 1 1 1 -0.0710953150608175 -0.473851413287049 1.13293529279595e-06 121.825823978252 22.7002900404496 5.36670781567861 1.71383835337507e-07 36.6131608448587 63.2491986584902 0.578871537053758 0.56315314456118 LYPLAL1 other 0.0100491360471001 1 0.00199856394770461 5.36670781567861 0.578871537053758 0.350854605275969 116.668552698186 83.9232207399049 1.39018202196702 0.165622820107752 -56.9888036325254 224.052657213168 -0.25435450907554 0.799416018243894 LHX9 other 1 1 1 1.39018202196702 -0.25435450907554 7.56480021534939e-27 383.082648658954 31.4812826763892 12.1685845077165 2.22511343406698e-27 -167.865402482926 124.647886737765 -1.34671679461427 0.179217764572133 PRUNE1 other 1.17012329731024e-22 1 3.49431813685879e-23 12.1685845077165 -1.34671679461427 0.93738549932528 -6.43653212912345 19.8706969775748 -0.323920803401483 0.746252537876994 -13.5249212403406 77.8457718151817 -0.17373995947334 0.862201976560972 RORC other 1 1 1 -0.323920803401483 -0.17373995947334 3.89050280572564e-08 641.532930572367 106.42605437894 6.02796875554671 5.498526358169e-09 246.894013663931 421.926206125723 0.58515922945626 0.558934853821619 TUFT1 other 0.00038216409060643 1 6.90339984268118e-05 6.02796875554671 0.58515922945626 5.4575449108285e-15 607.355716324476 70.6385377141628 8.59807883880788 7.60723816755118e-16 -149.288967285372 239.534326758825 -0.623246652391845 0.533666683258619 SF3B4 essential 7.2143286176242e-11 1 1.12419765640071e-11 8.59807883880788 -0.623246652391845 0.016529386701325 -322.443738180643 121.810295654564 -2.64709757453546 0.00860661587786774 418.435354990095 410.666017519011 1.0189188711499 0.309174316118377 ECM1 other 1 1 1 -2.64709757453546 1.0189188711499 7.31447202209923e-22 404.31479119834 37.3609003972426 10.8218695721846 7.18779262882663e-23 3.20446063173669 148.117329483267 0.0216346098253054 0.982755584361169 ZNF687 other 1.09314784370273e-17 1 1.11475475880472e-18 10.8218695721846 0.0216346098253054 0.0940254348771586 152.994066660903 70.0905205248135 2.18280682630598 0.0299212793122433 12.1468540453819 277.873943396549 0.0437135411003521 0.96516541870085 CGN other 1 1 1 2.18280682630598 0.0437135411003521 1.00378980828599e-16 268.286420950533 29.4174624573973 9.11997155903805 1.87396430839427e-17 -91.0474620109927 116.796775816627 -0.779537460468421 0.436353599943905 SNX27 other 1.38472804053052e-12 1 2.81788013053246e-13 9.11997155903805 -0.779537460468421 1.1877393350038e-25 471.955656156748 39.4064688847016 11.9766035758654 1.00458132792406e-26 52.9453706230452 156.027094599912 0.339334464689026 0.734625532707321 SETDB1 other 1.82698064510285e-21 1 1.57588672911448e-22 11.9766035758654 0.339334464689026 0.978208765507421 -20.8526122039694 102.772633513078 -0.202900436538059 0.839369141822437 -22.1285396378874 346.483258151218 -0.063866115078581 0.949125163952608 ADAMTSL4 other 1 1 1 -0.202900436538059 -0.063866115078581 0.00953625946234188 1077.01003089016 364.472987261317 2.95497902048355 0.00340923738649598 -874.753411489702 1228.76863049675 -0.711894322315235 0.477158826594185 MCL1 essential 1 1 1 2.95497902048355 -0.711894322315235 0.728731467049236 -77.9638487809095 117.693074320126 -0.662433615837471 0.508264755102943 -222.64643615386 466.594318702752 -0.477173482893818 0.633628933480968 CTSK other 1 1 1 -0.662433615837471 -0.477173482893818 8.73563289548642e-05 251.622125194535 57.9395343787729 4.34283996052825 1.99922551384975e-05 -107.382828661274 229.701345857317 -0.467488896334012 0.640531446027279 RFX5 other 0.652114995648061 1 0.200202442956914 4.34283996052825 -0.467488896334012 6.64310698158534e-22 560.858659000517 51.9063846627258 10.8051959820517 8.15652683825598e-23 -79.8415270492696 205.782917371595 -0.387989090975394 0.698333256658805 PI4KB other 9.93343786956455e-18 1 1.26434322519806e-18 10.8051959820517 -0.387989090975394 7.47817609753326e-31 667.942611966106 49.6412270472912 13.4554009176643 7.41557574862003e-32 -38.5680722872276 196.802697588626 -0.195973290812537 0.844780138999301 PIP5K1A other 1.17332582970297e-26 1 1.17195759131191e-27 13.4554009176643 -0.195973290812537 3.25150227401708e-08 646.673962604976 110.739176182739 5.83961326873024 1.53835157813936e-08 -561.375360678101 375.889917000741 -1.49345682150073 0.136516351857205 ANP32E other 0.000321085849559187 1 0.000189355695753173 5.83961326873024 -1.49345682150073 1.96096656659904e-05 70.0700252291238 15.5089546935942 4.51803661906792 9.39514689908293e-06 -75.4323805869166 61.4065966733343 -1.22840842309167 0.220379433538908 MINDY1 other 0.156642009339931 1 0.0966854567384625 4.51803661906792 -1.22840842309167 0.0531896082148247 10.892813911933 7.09011390763124 1.53633835137809 0.12564401777706 55.3131712633869 28.0727988246519 1.97034758126126 0.0498355815051683 ANXA9 other 1 1 1 1.53633835137809 1.97034758126126 0.615672571531746 -95.2377766730068 164.027490784978 -0.580620822870803 0.561985762537226 496.5242709314 650.28716220943 0.763546168194984 0.445811891822342 SELENBP1 other 1 1 1 -0.580620822870803 0.763546168194984 5.21531583082275e-20 1031.33238594795 101.888861093743 10.1221308676625 1.38877005478967e-20 -472.765481608616 403.421656862091 -1.17188919723819 0.242290095863407 CERS2 other 7.62479174466286e-16 1 2.13176203410214e-16 10.1221308676625 -1.17188919723819 8.21639974897934e-09 686.798510676959 116.577068706299 5.89136884550822 1.16300869600218e-08 -786.853675525435 393.022940157868 -2.00205533857483 0.0463016939630555 ENSA other 8.41523662290464e-05 1 0.00014400373673899 5.89136884550822 -2.00205533857483 2.79780062121867e-05 113.565544731813 24.9135345072881 4.55838751818177 7.86704379881783e-06 -76.0665647397698 98.6433576872932 -0.771127083699913 0.441316037447415 SEMA6C other 0.219907128827787 1 0.081447504449161 4.55838751818177 -0.771127083699913 1.5026357554883e-28 402.128059026818 31.5066866654337 12.7632608054593 2.00674784430912e-29 -74.8754364156007 123.431117870588 -0.606617178126054 0.544622373503611 MRPL9 essential 2.33960387129529e-24 1 3.16223325306232e-25 12.7632608054593 -0.606617178126054 8.85345100108632e-10 220.825355934608 33.5853216632892 6.57505555994074 2.56108480392528e-10 -135.978876302319 132.978678593576 -1.02256149437243 0.307444285479396 ARNT og 9.59271415967702e-06 1 3.37679031397548e-06 6.57505555994074 -1.02256149437243 1.55341287641217e-16 658.231475877571 72.6930606853717 9.05494237925285 2.95857480735834e-17 -231.867208964973 288.191716639596 -0.804558894574127 0.421790078084673 POGZ essential 2.13376792703976e-12 1 4.43845392599898e-13 9.05494237925285 -0.804558894574127 2.04647469206446e-11 142.488793214297 20.1953736190898 7.05551657036976 1.48947316247367e-11 -134.97920965406 79.962137164987 -1.68803904497394 0.0925757701403532 C1orf56 other 2.39846833909954e-07 1 2.03938665405895e-07 7.05551657036976 -1.68803904497394 4.46708557913374e-27 61.2103623047272 4.9438851651955 12.3810242874658 4.16566793594187e-28 -0.184285867813882 19.3682464628497 -0.00951484524772864 0.992415498482083 OAZ3 other 6.91504847649903e-23 1 6.54967969568141e-24 12.3810242874658 -0.00951484524772864 0.0417115456542353 24.1073024775797 11.1034379578226 2.17115658854072 0.0308069098436005 62.3464351124852 43.7906029277573 1.42374004795824 0.155698081697452 HORMAD1 other 1 1 1 2.17115658854072 1.42374004795824 1.8036438161705e-06 203.66868787477 40.2150358343276 5.06449102056795 7.69641631260228e-07 -165.472192124691 135.579250684208 -1.22048315866644 0.223370783325895 GOLPH3L other 0.0157476141589846 1 0.00859997558770178 5.06449102056795 -1.22048315866644 4.84677666094235e-11 154.356360266568 21.8189437506668 7.07441946000943 1.3281924154826e-11 -87.7090855077446 86.3905469585752 -1.01526253271439 0.310903262360254 GABPB2 og 5.59511897739185e-07 1 1.8210846208682e-07 7.07441946000943 -1.01526253271439 0.0322064240181256 24.787359363776 9.4783348472573 2.61515970507717 0.00942379950436031 17.3130758607192 26.0525612233428 0.664544100378388 0.506913515354379 SYT14 other 1 1 1 2.61515970507717 0.664544100378388 0.103252201884558 5.0146652215757 11.7320747129914 0.427432090593724 0.669404064251119 -65.1132798307009 32.0609418696526 -2.03092223851147 0.0432389603003911 KCNH1 other 1 1 1 0.427432090593724 -2.03092223851147 2.82817906159556e-10 248.475785519125 37.5861175154363 6.61083937219849 2.01236315879536e-10 -111.56481557377 102.433266447298 -1.08914632368158 0.277053386839688 DTL essential 3.14719765974354e-06 1 2.66416758592918e-06 6.61083937219849 -1.08914632368158 0.39527486970372 10.4123553376999 10.9421112003519 0.951585589567492 0.342148903813962 -27.1661921885926 30.939338101708 -0.878046973703451 0.380690322798434 DYRK3 other 1 1 1 0.951585589567492 -0.878046973703451 2.13801990655563e-10 292.090971360075 43.0299518787844 6.78808501071291 7.0635191479113e-11 -100.484566976326 121.669228661753 -0.825883159460794 0.409591526850112 EIF2D other 2.39479609733296e-06 1 9.48559986373008e-07 6.78808501071291 -0.825883159460794 2.13441898342333e-11 234.756215846994 34.9466985530898 6.71755060039107 1.07774172057599e-10 -191.943975409836 95.2400705625397 -2.01536994120342 0.0448494142104684 INTS7 essential 2.49855086199535e-07 1 1.43835410028072e-06 6.71755060039107 -2.01536994120342 0.250786955004516 22.3206065168298 29.0197002607662 0.769153585883399 0.442471972427546 -106.873732659426 79.0992455447766 -1.3511346653607 0.177779213817807 VASH2 other 1 1 1 0.769153585883399 -1.3511346653607 1.0119550166051e-10 48.8000057259557 7.03719215099198 6.93458480014316 2.96463705829729e-11 -17.1320768041532 19.699849435068 -0.869655215417844 0.385255629550732 TAF1A other 1.15089644038498e-06 1 4.02301248810943e-07 6.93458480014316 -0.869655215417844 1.18065168597751e-08 234.649069847079 41.8859751507813 5.60209160709254 5.18302643631991e-08 -215.505508503227 113.149880540506 -1.9046021743353 0.0578866330937479 SMYD2 other 0.00011970627444126 1 0.000622066832887116 5.60209160709254 -1.9046021743353 0.664610373252022 26.0421964766282 83.2978192964023 0.31263959484895 0.754794053087946 -191.384662073177 233.183130885138 -0.82074831634133 0.412508363949447 SUSD4 other 1 1 1 0.31263959484895 -0.82074831634133 0.213763559724052 32.1009966005844 41.9500552599001 0.765219411552709 0.444801915225001 -176.223533319639 116.297985059803 -1.51527589432458 0.130859506037899 DUSP10 other 1 1 1 0.765219411552709 -1.51527589432458 0.245426192239588 5.81206325786581 8.16252639947257 0.712042200346373 0.477048924946056 35.6862591679754 22.6096029105757 1.57836735607962 0.11564347119905 HHIPL2 other 1 1 1 0.712042200346373 1.57836735607962 0.000480968682491351 167.351288668213 48.0110720995113 3.48568114291113 0.000572400642214809 -214.284927491396 134.282706631922 -1.59577456298052 0.111704593720092 TP53BP2 other 1 1 1 3.48568114291113 -1.59577456298052 0.40869199634402 50.83311442575 44.5475493339244 1.14109788721955 0.25482917139786 -98.7444958521953 152.84114580309 -0.646059641422809 0.518783430268621 ATP8B2 other 1 1 1 1.14109788721955 -0.646059641422809 0.735999082945302 80.6114255613887 114.092296817146 0.706545733675462 0.480455844751499 -118.836570271828 437.772560527112 -0.271457329643365 0.786245983650997 CRNN other 1 1 1 0.706545733675462 -0.271457329643365 0.308345847515949 232.516063125558 158.329748291379 1.46855575553402 0.143121708830118 291.504688295643 530.279706056885 0.549718733276156 0.582968406292732 ADAM15 other 1 1 1 1.46855575553402 0.549718733276156 3.23111110303547e-09 579.94161756412 90.7791800049872 6.38848706864569 7.19565004064248e-10 -243.346223076691 311.68849709035 -0.780735334631716 0.435634622412425 JTB other 3.38749688042239e-05 1 9.34355157777426e-06 6.38848706864569 -0.780735334631716 0.066011193378833 59.6129259925154 51.3490463565119 1.16093540625133 0.246682289192798 -347.947225796936 176.3059226246 -1.97354246877913 0.0494420988835829 RAB13 other 1 1 1 1.16093540625133 -1.97354246877913 0.479768246197104 -1674.27214139638 2444.80777630207 -0.684827722500465 0.494035779544497 -8647.00719485445 8330.8093279203 -1.03795523993982 0.300212715569248 S100A8 other 1 1 1 -0.684827722500465 -1.03795523993982 8.10855960204233e-09 1295.80106379333 212.816547822723 6.08881723273105 3.84553819497621e-09 -1005.19633333022 730.70135622702 -1.37565959713083 0.170054658733831 TPM3 other 8.30884102421278e-05 1 4.86114483226942e-05 6.08881723273105 -1.37565959713083 1.01565996323528e-12 250.563778238256 32.1204378369131 7.80075849247316 1.31037163603991e-13 -22.9054319209049 109.280512672951 -0.209602163831855 0.834134519716348 SNAPIN other 1.25139464070219e-08 1 1.87684529429996e-09 7.80075849247316 -0.209602163831855 0.171615015045914 45.3627460450508 32.9819402006877 1.37538136838005 0.170140759480033 153.481122913726 113.242831359695 1.35532749464928 0.176433513324349 SLC27A3 other 1 1 1 1.37538136838005 1.35532749464928 0.622365880074827 875.031314041094 1165.21632120009 0.750960399473184 0.453325676455811 -2300.33226664406 3970.53506283485 -0.579350699651468 0.562832066279409 S100A7 other 1 1 1 0.750960399473184 -0.579350699651468 1.76517783865708e-10 895.966624808758 128.923519561009 6.94959793108011 2.69091443201153e-11 -163.398966120021 442.656323282076 -0.369132795638157 0.712314877006566 UBAP2L other 1.98353033729896e-06 1 3.65775998743327e-07 6.94959793108011 -0.369132795638157 2.17957844408417e-06 443.236092631658 91.9045301924922 4.82278829676088 2.35550014682934e-06 -560.51381155216 315.552364428924 -1.77629412654397 0.0767981465743591 SLC39A1 other 0.0188707901688807 1 0.0254252685848759 4.82278829676088 -1.77629412654397 1.73445473638323e-13 625.479334864316 77.4562909061603 8.07525544467518 2.17177301225922e-14 -50.0321734641625 265.944624102219 -0.188130042609667 0.85091447338134 HAX1 other 2.19408524152479e-09 1 3.1484193358722e-10 8.07525544467518 -0.188130042609667 4.9433098534669e-08 153.32584980385 26.4088920746616 5.80584181155257 1.77522458667995e-08 -104.366027165056 90.6744022155776 -1.15099768639143 0.250740292419112 CREB3L4 other 0.000482417608599835 1 0.00021782005678563 5.80584181155257 -1.15099768639143 0.671161906608964 4.69040135901092 37.8648254423595 0.123872256222361 0.901508927844047 -110.973530381575 126.817283057368 -0.875066297796131 0.382318474628969 EFNA3 other 1 1 1 0.123872256222361 -0.875066297796131 0.984015307428086 2.72754279967326 16.2217093749463 0.168141515584408 0.866596903585498 4.07009688847367 54.9211963090261 0.0741079430530316 0.940978965415885 KCNN3 other 1 1 1 0.168141515584408 0.0741079430530316 1.52349879000243e-11 1532.3718478034 211.43546923276 7.24746823872051 4.36521329385038e-12 -788.463291236531 725.959450538453 -1.08609825335522 0.27839359858386 C1orf43 other 1.79559567389686e-07 1 6.05847953053495e-08 7.24746823872051 -1.08609825335522 1.89625477340831e-06 207.228192081065 39.4370897625373 5.25465224053928 2.99201858158493e-07 4.9435302524666 135.406458144116 0.0365088218111805 0.970903325747343 GATAD2B other 0.0165277566050268 1 0.00343753014838293 5.25465224053928 0.0365088218111805 3.00839311761155e-12 1743.56777709573 235.853352523085 7.39259272104291 1.76784194101447e-12 -1295.4151858003 809.797763954271 -1.59967740522614 0.110826778444207 ILF2 essential 3.63895231506293e-08 1 2.47710012774947e-08 7.39259272104291 -1.59967740522614 5.95670439939787e-10 728.853436185132 107.457687421605 6.78270167238487 7.42679418095971e-11 194.039140823853 352.54943053089 0.550388467601997 0.582508012250259 RIT1 other 6.51663461294127e-06 1 9.96155903492125e-07 6.78270167238487 0.550388467601997 0.000586181164724973 310.872804407233 79.7542936053242 3.89788173594305 0.000122174602933018 -33.5961002554059 273.834770362327 -0.122687488557253 0.902444840081765 INTS3 essential 1 1 1 3.89788173594305 -0.122687488557253 6.51437999016942e-05 39.9938623291846 9.85930843287447 4.05645716446305 6.53241334835485e-05 -53.1553252276845 33.0209024780816 -1.60974780331845 0.108625770938095 HCN3 other 0.493399140455432 1 0.624564040236207 4.05645716446305 -1.60974780331845 0.371112569454817 9.52541326890165 9.70183785494759 0.981815343784995 0.327066528686137 45.9155575690458 41.7500627109074 1.09977218206789 0.272407384988642 FLG other 1 1 1 0.981815343784995 1.09977218206789 0.198724147801393 3.08848680935788 2.07134199190984 1.49105595378299 0.137105583823717 -4.83942923510866 5.83599924386597 -0.829237467807288 0.40769716412561 ACTA1 other 1 1 1 1.49105595378299 -0.829237467807288 9.13592713245916e-13 115.676209667907 14.8416525998613 7.79402488298293 1.38229087586048e-13 2.25239661438257 41.8552073083589 0.053814011666184 0.957122849233232 C1orf131 other 1.12773884523076e-08 1 1.97833470153151e-09 7.79402488298293 0.053814011666184 0.339130544838702 34.7953260328534 291.968813635201 0.119174803636145 0.905224837989665 -1187.972535258 822.621171328836 -1.44413075746518 0.149853055071648 GALNT2 other 1 1 1 0.119174803636145 -1.44413075746518 6.40917587125423e-05 61.7810652065703 13.8454229318772 4.4622013722909 1.18884861241944e-05 8.38415961506554 39.009433534893 0.214926464070956 0.829985706932841 TTC13 other 0.48607189807592 1 0.121345777869652 4.4622013722909 0.214926464070956 0.197458711659461 96.3748184780667 66.1982448617351 1.45585156644802 0.146599740715728 -160.84567771297 181.629540131163 -0.885570032258059 0.376640197889281 SCCPDH other 1 1 1 1.45585156644802 -0.885570032258059 0.154930446188835 103.862487144327 59.7752638860133 1.73754962156895 0.0834179294326788 175.669409210376 161.899129320604 1.08505468774019 0.278854676844223 LYST other 1 1 1 1.73754962156895 1.08505468774019 2.43456950009286e-06 126.489067752182 24.3667244848593 5.19105749444404 4.1077806600796e-07 68.1266382952478 66.3018803998047 1.02752196294343 0.305090991861013 MAP3K21 other 0.0209762508128 1 0.00467752983763264 5.19105749444404 1.02752196294343 3.8386327957208e-12 429.375553149689 62.4255725985273 6.87819967485279 4.43962308983953e-11 -161.614268706775 185.305368179576 -0.872151035312464 0.383924525993243 ACP1 other 4.62593638212313e-08 1 5.99571098282829e-07 6.87819967485279 -0.872151035312464 4.00290280918033e-09 233.549263743876 36.8471953381771 6.33831860472424 9.56396121263639e-10 -36.1380723942432 102.118085912993 -0.353885132796494 0.723698123510802 SNAP47 other 4.17342646885141e-05 1 1.23651748562493e-05 6.33831860472424 -0.353885132796494 2.70264901021208e-08 954.491612518672 168.467195389304 5.66574169121162 3.74787107717405e-08 -730.856197928234 455.386209216438 -1.60491508775767 0.10968147803483 SRP9 essential 0.000268318993733856 1 0.00045240551772568 5.66574169121162 -1.60491508775767 1.32248496287042e-09 111.167471445816 17.4853920381024 6.35773399896164 8.6935703455978e-10 -68.0192682700343 48.8613320405375 -1.3920878827782 0.165041347343698 NVL essential 1.41955535914511e-05 1 1.125643488348e-05 6.35773399896164 -1.3920878827782 9.77904419276884e-10 196.386611080485 30.0907204576869 6.52648418161475 3.33384767077974e-10 -63.4376952407202 81.168028868166 -0.781560130575012 0.435160456937934 SDE2 essential 1.0567235154706e-05 1 4.37967568510335e-06 6.52648418161475 -0.781560130575012 0.0416925686264248 294.719922908569 120.256329453393 2.45076433189151 0.01488757585571 -150.364182075666 336.346278107505 -0.447051719798147 0.655194794244882 DEGS1 other 1 1 1 2.45076433189151 -0.447051719798147 3.16145443151778e-09 191.169013164342 30.3368887532301 6.3015365457998 1.18811167601582e-09 -87.0957873529317 84.8495847818553 -1.02647275855093 0.30558413188773 FBXO28 other 3.31763028043476e-05 1 1.5317135727196e-05 6.3015365457998 -1.02647275855093 3.54990865621243e-09 417.032666188962 64.552857289642 6.46032853848405 4.84854793588544e-10 72.8696470279349 178.125065120882 0.409092605684007 0.682796018854323 CNIH4 other 3.71178449093571e-05 1 6.33268845905997e-06 6.46032853848405 0.409092605684007 0.0875460741934873 234.929548728778 106.406905804989 2.2078411824072 0.0280899433885078 142.5523521707 294.669131235792 0.483770904583253 0.628937703004645 ITPKB other 1 1 1 2.2078411824072 0.483770904583253 6.03149177194261e-05 744.510785973337 175.86606693385 4.23339646444345 3.1479299073094e-05 -461.651939189665 492.594433991987 -0.937184643862977 0.349491924637484 GUK1 essential 0.458393374667639 1 0.309976657972756 4.23339646444345 -0.937184643862977 0.000536297774636463 163.252684641236 45.8280292127305 3.56228900621993 0.000433680377520253 -152.952638464893 127.007512550622 -1.20428024605182 0.229524334927879 CDC42BPA other 1 1 1 3.56228900621993 -1.20428024605182 0.152712422681266 13.2120084163389 14.9388385691785 0.884406666231582 0.377263597589584 75.1948192839184 41.2217476451229 1.82415408321037 0.0692340166104257 CNIH3 other 1 1 1 0.884406666231582 1.82415408321037 1.29546048367851e-06 113.428162438111 22.2232257442327 5.10403681911694 6.23932817077055e-07 -55.6433493240296 61.5893083580797 -0.903457934622673 0.367079402016702 C1orf35 other 0.0114389160708813 1 0.00701238093112902 5.10403681911694 -0.903457934622673 0.0207468118549852 -20.1281483047942 95.3327129417481 -0.211135796765726 0.832939989318523 -778.712299282443 286.914099840884 -2.7140956115935 0.00707192154161538 MBOAT2 other 1 1 1 -0.211135796765726 -2.7140956115935 3.70367013079279e-06 1068.04541031463 221.243502977461 4.82746564731186 2.31755407837679e-06 -652.736029674727 610.499341561526 -1.06918383892957 0.285941767092371 PARP1 other 0.0314441594104308 1 0.0250319016005477 4.82746564731186 -1.06918383892957 0.0123198146514458 65.7873170064011 22.3137868089791 2.94828114876173 0.00347294542525367 53.7461089850069 61.7928331233767 0.869779006210905 0.385188083137146 PSEN2 other 1 1 1 2.94828114876173 0.869779006210905 1.89825453924518e-06 436.934776880668 86.4277425850941 5.05549218123423 7.91297802840367e-07 -205.525915218003 238.684323840728 -0.861078398073388 0.389956072262641 LBR other 0.0165432883095217 1 0.00883563126651554 5.05549218123423 -0.861078398073388 0.731503693716479 0.641302172853437 30.2889079610129 0.0211728390366171 0.983123247301314 -65.6252071522024 83.9424894347051 -0.781787716734909 0.435016835467076 WNT9A other 1 1 1 0.0211728390366171 -0.781787716734909 0.0713301081283845 1056.08435887068 480.056225426946 2.19991805737221 0.0286600976544689 1227.65507206761 1297.64720189441 0.946062281238982 0.344962706592481 EPHX1 other 1 1 1 2.19991805737221 0.946062281238982 0.000999222071100809 269.528085303158 71.9393725289375 3.74660044740787 0.000218863893227134 148.344822239752 211.760504128201 0.700531115802141 0.484194470027179 SOX13 other 1 1 1 3.74660044740787 0.700531115802141 0.0232191564911593 95.2799145880371 37.7287988245645 2.52538955801588 0.0121255517943857 148.670001541405 111.058370102234 1.33866543696389 0.181797400936833 ETNK2 other 1 1 1 2.52538955801588 1.33866543696389 0.0351392804806347 69.8617157065892 26.8305019734925 2.60381694593749 0.0097256425915654 17.3978219827785 76.5292781857181 0.227335503420771 0.820333646004162 PPFIA4 other 1 1 1 2.60381694593749 0.227335503420771 0.0724223337854642 58.4195490942133 38.3863866405318 1.52188195365408 0.129200333733972 209.734940087455 112.889980919233 1.85787027670339 0.0642679160596292 PLEKHA6 other 1 1 1 1.52188195365408 1.85787027670339 0.887587376850163 -10.4718987933162 29.4441690954487 -0.355652718858175 0.722375309705684 23.9398154569413 80.4802947720163 0.297461826211718 0.766340174113692 PTPN7 other 1 1 1 -0.355652718858175 0.297461826211718 0.764995499687375 4.39358716591711 22.0370587304536 0.19937266672732 0.842119654002611 -42.3978057234525 62.1784864392379 -0.681872592136583 0.495897592729798 SYT2 other 1 1 1 0.19937266672732 -0.681872592136583 0.000926821398387934 134.795029820348 36.0378692687441 3.74037179654395 0.000223927764816144 -20.2344456043274 98.5029780362263 -0.205419633068208 0.837397370085514 ARL8A other 1 1 1 3.74037179654395 -0.205419633068208 0.642414847650986 2.51484629866865 15.4827516143487 0.162428899029679 0.871090514960648 -44.0230054959398 50.4981285425524 -0.871774989816577 0.384111445760039 OSR1 other 1 1 1 0.162428899029679 -0.871774989816577 0.739008360347891 4.4143530019675 6.19497923480296 0.712569459017388 0.476727544610735 -3.10731448331862 20.2689991146753 -0.153303794910565 0.878273219664203 GDF7 other 1 1 1 0.712569459017388 -0.153303794910565 2.52213062376576e-11 3354.16838032523 459.626243228575 7.29759979927252 3.22368820572406e-12 2391.80329896715 1424.58049086301 1.67895272629923 0.0943096076610949 PDIA6 other 2.94433529018414e-07 1 4.49059767057361e-08 7.29759979927252 1.67895272629923 0.0736277361677631 368.420056839634 320.045550038107 1.15114881864712 0.250689409866219 -1773.79618476005 1047.13877553207 -1.69394566050593 0.0914287902633486 RHOB other 1 1 1 1.15114881864712 -1.69394566050593 1.08733595006976e-09 1347.02612351999 203.474636363037 6.62011810217287 1.91719999196216e-10 679.523404568914 630.65337786236 1.07749110434039 0.282219114851711 ATP6V1C2 other 1.17203942058019e-05 1 2.54105686934664e-06 6.62011810217287 1.07749110434039 2.82612794311278e-07 125.748649198916 22.3995192371498 5.61389947112619 4.8756924319132e-08 80.4364442217037 82.4778136504953 0.975249472089039 0.330303060189789 HNRNPLL other 0.00262773376150626 1 0.000586399528786201 5.61389947112619 0.975249472089039 0.184926922207401 45.5223880597015 25.8505100039812 1.76098607155877 0.0793644083288805 -40.8388059701492 95.1847905441885 -0.429047600322136 0.668228203497959 GALM other 1 1 1 1.76098607155877 -0.429047600322136 1.9894982442102e-05 30.5761121306847 7.65906910935646 3.99214469723643 8.4293058446029e-05 93.8215952404964 30.8083951825889 3.0453256225926 0.00255231124796322 CAMKMT other 0.158781854870416 1 0.796485109256528 3.99214469723643 3.0453256225926 1.64634840917652e-06 547.260271797956 111.185177483111 4.92206141309693 1.48355043327912e-06 1132.38786129484 447.637199677148 2.52970008326288 0.011978975001383 EML4 other 0.0144137803223404 1 0.0162508114461395 4.92206141309693 2.52970008326288 2.92547977722127e-06 2146.8989490033 424.758824591779 5.05439516428318 8.00607055487974e-07 -996.967573311371 1960.9254507575 -0.508416866600537 0.611579271850109 CALM2 other 0.0250421068930141 1 0.00893797716746774 5.05439516428318 -0.508416866600537 4.60606163878917e-08 66.9114359802587 11.1613050892596 5.99494731531411 6.50055255207083e-09 9.97076361510484 53.1748500843268 0.187509012235912 0.851402391074265 CHAC2 other 0.000450518888889969 1 8.13284129789582e-05 5.99494731531411 0.187509012235912 3.96198666272139e-09 998.80940581843 154.790539053234 6.4526515116982 5.17311433307398e-10 278.683279093403 762.169993720604 0.365644516826206 0.714920951407173 RPS27A essential 4.13195589055213e-05 1 6.75143151609484e-06 6.4526515116982 0.365644516826206 2.26660239622657e-15 54.7248973040969 6.25192100393074 8.75329315096751 2.59835795499594e-16 -16.2842344980155 39.111968515607 -0.416349141095201 0.677495402469653 WDPCP other 3.02568753872285e-11 1 3.86557712964747e-12 8.75329315096751 -0.416349141095201 2.52542286810538e-19 252.940491013987 25.2044221808839 10.0355599981113 2.82284230004998e-20 182.203212551364 157.744355414909 1.1550537708441 0.249116755954114 VPS54 other 3.65630722844297e-15 1 4.32572354059659e-16 10.0355599981113 1.1550537708441 2.1721393175103e-06 203.920966090347 41.4139761497088 4.92396492800368 1.4731690722073e-06 307.264237328187 156.009199207516 1.96952640542356 0.0499073361665009 ASXL2 other 0.0188128986289567 1 0.0161444598623198 4.92396492800368 1.96952640542356 2.69380178422298e-14 108.944807680594 12.9880223908188 8.38809823407806 2.85633361301883e-15 20.220622150585 71.1505347104868 0.28419494291734 0.776480442444423 ETAA1 other 3.4938609141372e-10 1 4.19281211055034e-11 8.38809823407806 0.28419494291734 6.48332627952488e-06 185.917571962591 37.2773787848589 4.98741000636306 1.08998754134735e-06 -4.0397016041812 172.247599963579 -0.0234528760054444 0.981306160618171 SNRPG essential 0.0538764413828517 1 0.012053082232219 4.98741000636306 -0.0234528760054444 0.00234602090927743 14.3350362107716 4.07916400598497 3.51420933057342 0.000516130627812253 4.83941646549571 15.2227053348235 0.317907780453783 0.75079792602324 ABHD1 other 1 1 1 3.51420933057342 0.317907780453783 0.186985293286059 55.4712314024174 31.6885337884844 1.75051429557071 0.0811824770308873 -90.3394280578091 184.605726399223 -0.489364169898196 0.624987186979387 MEIS1 other 1 1 1 1.75051429557071 -0.489364169898196 2.51896273579127e-18 365.509678552911 38.9777064948696 9.37740342934289 3.2037956238919e-18 -199.967178199365 176.313008507111 -1.13416009341875 0.25775619252926 CIAO1 essential 3.59002569104972e-14 1 4.84798353807322e-14 9.37740342934289 -1.13416009341875 0.000351907557914785 80.9502214655416 22.1081307479186 3.66155883500747 0.000304081813782955 -112.498994717907 98.214880294923 -1.14543737547804 0.253089403886088 ZNF514 other 1 1 1 3.66155883500747 -1.14543737547804 7.18419615142885e-11 2046.5972933478 293.463926817029 6.97393139778924 2.47137643295603e-11 -611.939560290436 1327.46414497814 -0.460983871093945 0.645189713647488 SNRNP200 essential 8.22590459338603e-07 1 3.36206049939339e-07 6.97393139778924 -0.460983871093945 1.33414291632735e-13 293.008917800548 37.7698189182862 7.75775278230652 2.01410875777229e-13 -220.882438897817 167.791582477847 -1.31640953399423 0.189204885390534 MRPS5 essential 1.69435005589786e-09 1 2.87796000398082e-09 7.75775278230652 -1.31640953399423 0.00342863915690609 3.94100501667552 2.2327725925579 1.76507228269075 0.0786696289092364 30.4191626595987 10.1236830574998 3.00475256750197 0.0029049176090092 ANKRD53 other 1 1 1 1.76507228269075 3.00475256750197 8.44924303468797e-08 99.1944229740177 16.9381925684812 5.85625783701385 1.36185012690163e-08 72.9694373426883 72.5675972653648 1.00553745876212 0.315531806628221 TPRKB other 0.000812901672367329 1 0.000168025068657123 5.85625783701385 1.00553745876212 2.84709457372098e-05 218.877844257434 47.3719569856144 4.62040958797421 5.91868327099857e-06 183.095304944291 207.88276600878 0.880762308774352 0.379224047744094 EXOC6B other 0.223610807820046 1 0.0618620775484771 4.62040958797421 0.880762308774352 0.0224901251093813 46.000607000742 17.048358873262 2.69824253130239 0.00740661101230926 58.5247665937625 74.876162575849 0.781620806681663 0.435117272138027 SFXN5 other 1 1 1 2.69824253130239 0.781620806681663 1.45910224601174e-07 358.291864017263 62.4281682747547 5.73926600633824 2.52466296593728e-08 275.208746551786 283.057482692336 0.972271582203389 0.331776117951427 TEX261 other 0.00138235346787152 1 0.000307301976213886 5.73926600633824 0.972271582203389 0.0598851414564429 32.9431112576439 17.435871091246 1.88938717688637 0.0599113503126454 116.425813845779 75.1224156757671 1.54981456331596 0.122357350461891 DQX1 other 1 1 1 1.88938717688637 1.54981456331596 5.41424698459813e-07 161.978833462156 29.7401284305317 5.44647390614043 1.1496775180853e-07 165.808383375945 127.414401143544 1.30133157545627 0.194246166935388 DUSP11 other 0.00492750618068276 1 0.00135523985831895 5.44647390614043 1.30133157545627 0.391911133933441 19.4286385777023 21.9477847803813 0.885220935602995 0.376819361178421 -61.2427998027658 76.6627806734728 -0.798859619554047 0.425068807906281 ST6GAL2 other 1 1 1 0.885220935602995 -0.798859619554047 0.358462096203544 11.2252153256952 9.47778804139207 1.18437079165219 0.237300208652884 -14.7873955690578 30.7075285021118 -0.481556031708666 0.630508564460514 NPHP1 other 1 1 1 1.18437079165219 -0.481556031708666 0.763201274448439 28.2936186028472 144.327338102945 0.196037832989521 0.844726932566787 343.919137727647 467.612889112379 0.735478310660925 0.462681950028465 MALL other 1 1 1 0.196037832989521 0.735478310660925 0.0175868604110313 126.155759514988 44.718717864237 2.82109518206645 0.00514533769139252 171.4296881501 174.353392239388 0.983231160278923 0.326383792703813 THNSL2 other 1 1 1 2.82109518206645 0.983231160278923 7.79457146773786e-08 742.072782510102 135.344859647551 5.48282945094862 9.55857442350848e-08 -176.536075093758 409.71754148749 -0.430872631063926 0.666902232412827 RALB other 0.000751474635204607 1 0.00113135286876646 5.48282945094862 -0.430872631063926 6.121399154364e-12 77.4125359769748 12.5817227569245 6.15277712540357 2.71352261472789e-09 -88.2134633834345 38.0875382269281 -2.3160715417692 0.0212980352457558 TMEM177 other 7.31201128988779e-08 1 3.44915859558062e-05 6.15277712540357 -2.3160715417692 0.00142999286000863 8.37584696574266 2.31911564214082 3.61165558695933 0.000362224446044142 2.38055621876621 7.34838423231298 0.323956415928582 0.746219993189054 NT5DC4 other 1 1 1 3.61165558695933 0.323956415928582 0.0529921903177391 42.3743789468795 20.5411743002412 2.06289953668237 0.0400783541913695 -42.7561234676821 62.3809750844407 -0.685403256518613 0.493677523504302 RABL2A other 1 1 1 2.06289953668237 -0.685403256518613 0.208593954388438 119.967238994591 86.1117946488742 1.39315687803006 0.164709834278715 -193.953070070721 272.855110161659 -0.71082806532672 0.477799854870531 SLC20A1 other 1 1 1 1.39315687803006 -0.71082806532672 0.744786477834139 4.19597192718281 13.1065755552266 0.320142504768116 0.749106091546024 -25.2552582752965 42.4701588087573 -0.594658908364827 0.552565824049248 FBLN7 other 1 1 1 0.320142504768116 -0.594658908364827 7.49011655944875e-09 90.5629890559037 16.1096420693701 5.6216636388275 4.68336484960639e-08 -73.2244158218828 52.201206497875 -1.40273416525083 0.161836492651713 ZC3H8 essential 7.69160069489792e-05 1 0.000563549292353136 5.6216636388275 -1.40273416525083 4.54315736174886e-05 21.5937128446286 4.79372383898937 4.50458006550102 9.88092042464042e-06 28.9023336905581 20.494687286533 1.41023540815623 0.159612693613836 LIPT1 other 0.349277937971252 1 0.101516576442756 4.50458006550102 1.41023540815623 8.06808769620788e-06 69.6330666494521 14.2119193350327 4.89962439329393 1.67028586504707e-06 3.68086345513971 64.594052898234 0.0569845564720764 0.954600278494928 FAHD2B other 0.0666182001075885 1 0.0182278296452587 4.89962439329393 0.0569845564720764 0.28410216589355 0.785169377784937 1.77213237281204 0.443064744954139 0.658071078713075 -10.8278681483868 7.54887317974505 -1.43436879790746 0.152615724845679 LYG1 other 1 1 1 0.443064744954139 -1.43436879790746 0.246809468982048 3.46828528072843 20.3224120248331 0.170663072694832 0.864616047519519 139.746282245827 83.6152335873666 1.67130170245606 0.0958164003602374 AFF3 og 1 1 1 0.170663072694832 1.67130170245606 3.02408610878831e-08 579.770109858581 137.573787317282 4.21424837655646 3.42432395515645e-05 -833.397914599597 332.714462818551 -2.50484426658091 0.0128423639158607 UBXN4 other 0.000299384524770042 1 0.335994666479951 4.21424837655646 -2.50484426658091 2.22140909680311e-07 82.8768908933454 24.4829447313106 3.38508671252099 0.000819334584533738 -177.36334715637 59.0374872830824 -3.00424959324436 0.00291721204821045 SPOPL other 0.00207990533733675 1 1 3.38508671252099 -3.00424959324436 0.812256650979971 -1.2297035189803 20.7590962167358 -0.0592368524208161 0.952807935064898 -31.1297184389453 50.1647348053126 -0.620549845618811 0.535427155324142 THSD7B other 1 1 1 -0.0592368524208161 -0.620549845618811 1.97129432647654e-08 252.99965990524 48.5060026919601 5.21584228475654 3.63860135049374e-07 -179.891365917017 131.259882510556 -1.37049769111708 0.171665718378821 POLR2D essential 0.000197168858534184 1 0.00415601046253395 5.21584228475654 -1.37049769111708 5.75188004980581e-14 139.206082109651 24.3038311994067 5.72774230398082 2.70946766516336e-08 -245.786224501745 65.7461366766459 -3.73841318936466 0.000226072306296598 AMMECR1L other 7.38771473597058e-10 1 0.000329471268083865 5.72774230398082 -3.73841318936466 0.107926372928385 78.022191762353 36.8433185687754 2.11767546445929 0.0351065357644798 64.9136013302471 98.2734107422747 0.660540840497387 0.509463789657553 GALNT13 other 1 1 1 2.11767546445929 0.660540840497387 1.29660804314681e-08 489.00652797144 97.7654472664597 5.00183389575923 1.0199256718568e-06 -440.103608678677 257.754696221483 -1.7074513680267 0.088879269066852 PKP4 other 0.000131164869644731 1 0.0113048561468607 5.00183389575923 -1.7074513680267 0.52792789785561 -7.756363906857 7.33814922635059 -1.05699184734546 0.291456617223915 -13.7408039943297 17.6880025249194 -0.776843172369027 0.437928840728392 SCN1A other 1 1 1 -1.05699184734546 -0.776843172369027 5.00084256916757e-10 92.6466241681748 15.6978003073695 5.90188576450936 1.07442401058335e-08 -61.9447169827822 45.5144072752148 -1.36099140230954 0.174651260960857 SCRN3 other 5.49592598351516e-06 1 0.000133228577312336 5.90188576450936 -1.36099140230954 5.91837123479861e-09 261.960668827046 45.3548133789326 5.77580744602352 2.11794114562344e-08 -96.8843127429039 130.916369333641 -0.740047354170002 0.459919055470514 LNPK other 6.11486115979392e-05 1 0.000258685331526448 5.77580744602352 -0.740047354170002 0.602202907242108 -24.9609217837934 25.0632703041744 -0.995916394024448 0.320185776981876 -11.9732113649282 65.4116730839554 -0.183043955313001 0.854901413456053 ZNF385B other 1 1 1 -0.995916394024448 -0.183043955313001 5.21687634494949e-06 262.224557222133 52.5572847978382 4.98930944075176 1.08678357944728e-06 132.097187720666 160.365195171295 0.823727290573026 0.410821539807347 CDCA7 other 0.0437487250287464 1 0.0120198263886869 4.98930944075176 0.823727290573026 0.232363565436239 20.9703040182361 17.0021370983651 1.23339224339348 0.218502126436205 -35.4427942659028 50.3646947680142 -0.703723003368859 0.482211722635013 DLX1 other 1 1 1 1.23339224339348 -0.703723003368859 1.21287630548089e-11 232.260340988837 36.4882371610738 6.3653483714093 8.28611084398821e-10 -122.351313417916 97.5129769558783 -1.25471826660852 0.210662066951082 UBR3 other 1.43446880649224e-07 1 1.07363138205555e-05 6.3653483714093 -1.25471826660852 9.26532164547941e-06 13.6850604132947 3.07469304759497 4.45087044509992 1.24883126149862e-05 -2.74774720517933 8.21789991145931 -0.33436124007154 0.738364650051861 PHOSPHO2 other 0.0761794745691317 1 0.127218440608865 4.45087044509992 -0.33436124007154 0.00606245977014773 224.273355284053 72.3850788022383 3.09833682569837 0.00215307751839971 8.87625510830736 181.66522641155 0.0488605072288231 0.961066854804424 GULP1 other 1 1 1 3.09833682569837 0.0488605072288231 0.380893766700223 87.5609540141565 63.1019408081197 1.38761110819732 0.166403877391893 51.0740953708836 155.887006625144 0.32763535894752 0.743442225952105 FAM171B other 1 1 1 1.38761110819732 0.32763535894752 4.73739086348732e-18 3387.94177234232 356.57120260857 9.50144528654345 1.19752381668714e-18 908.425678943673 888.624810066785 1.02228259739383 0.307565633375484 HSPD1 essential 6.71762024442502e-14 1 1.81855966802109e-14 9.50144528654345 1.02228259739383 0.00377242277007166 26.216135984006 9.12620024785618 2.87262335605274 0.00439277098313282 -21.0086872419791 22.7553806189113 -0.923240423608622 0.356703195303193 CCDC150 other 1 1 1 2.87262335605274 -0.923240423608622 1.32091754039635e-12 76.6274445771439 15.7326087994897 4.87061272251488 1.89742069555907e-06 -86.611888648371 27.3601651567908 -3.16562009593257 0.00172482768419801 METTL21A other 1.61997327154208e-08 1 0.0206401423262915 4.87061272251488 -3.16562009593257 0.667564890443318 -3.17992079106731 26.2860755755118 -0.12097358473814 0.903802945974965 -38.3361381812607 45.5901299617421 -0.840886793115774 0.401163782859403 UNC80 other 1 1 1 -0.12097358473814 -0.840886793115774 0.222307998769359 35.479555601263 24.5031549163918 1.44795866990696 0.148797446508248 -7.44531221642813 42.6927519386869 -0.174392885872541 0.861688370805079 PTH2R other 1 1 1 1.44795866990696 -0.174392885872541 0.504862729145785 293.034428776933 263.887779912794 1.11045092301648 0.267800077078649 417.843945443213 609.615667956804 0.685421926315747 0.493670149761604 NBEAL1 other 1 1 1 1.11045092301648 0.685421926315747 5.3024891942195e-09 47.0784168433966 20.5428388028202 2.29171913849286 0.022700551439944 -147.976799448093 35.6291561329979 -4.15325018913497 4.41501664860029e-05 KANSL1L other 5.49284855629198e-05 0.667903718600251 1 2.29171913849286 -4.15325018913497 6.27564035647759e-09 48.8182296990234 19.8622501648489 2.45783983656691 0.0146038855237509 -111.740148885213 30.7773169272043 -3.63060071641413 0.000338003302672779 SPAG16 other 6.47534182077594e-05 1 1 2.45783983656691 -3.63060071641413 0.169625887797059 -73.4503511300563 131.709233590155 -0.557670477064763 0.577526408072281 -360.566173331101 198.114821742198 -1.81998585547677 0.0698561770093498 ABCA12 other 1 1 1 -0.557670477064763 -1.81998585547677 1.47005733197262e-05 99.3418429136401 40.8892959262395 2.42953175551967 0.015790917095163 -358.896423577844 114.95803910368 -3.12197760483857 0.00199771633105505 SUMF1 other 0.118765931850068 1 1 2.42953175551967 -3.12197760483857 2.03456649626494e-09 40.0346648379909 28.1090764070327 1.42426112684281 0.155512930332669 -196.740705183153 42.3691600693404 -4.64348844445279 5.32944031730491e-06 RHBDD1 other 2.16193035893113e-05 0.0824357828280724 1 1.42426112684281 -4.64348844445279 0.365170391443431 237.780401576311 614.099197503846 0.387201941547598 0.698908390609145 -953.805632085034 971.014873987028 -0.982277056342781 0.32683308175028 ACKR3 other 1 1 1 0.387201941547598 -0.982277056342781 0.204868012970423 33.7908018867923 26.1505218489175 1.2921654903109 0.19739255693704 -13.6841793524871 40.0273672097854 -0.341870582713264 0.732711306959137 TRPM8 other 1 1 1 1.2921654903109 -0.341870582713264 0.0686037893287241 345.837368473742 209.292276172649 1.6524134325361 0.0996041197445705 -189.429265972474 334.561803842035 -0.566201113806508 0.571723914989017 HES6 other 1 1 1 1.6524134325361 -0.566201113806508 0.107812417557824 16.4284863006946 14.7077594723632 1.11699449066764 0.264986009640712 -23.0748000634075 23.4742444250743 -0.982983718051425 0.326492212548275 ESPNL other 1 1 1 1.11699449066764 -0.982983718051425 7.7702660919197e-08 21.117745024565 15.6556981144359 1.34888555401389 0.178491520406541 -105.720773813579 25.1489898165788 -4.20377814713995 3.56089217618052e-05 ANKMY1 other 0.000749286759243817 0.539866862830729 1 1.34888555401389 -4.20377814713995 6.35074983585414e-13 173.028773788024 44.4032502667689 3.89675919552038 0.000122711883863879 -257.81026942086 68.89777809927 -3.74192429035084 0.000222616091515783 COPS7B other 7.88763129613085e-09 1 1 3.89675919552038 -3.74192429035084 4.93408559231034e-14 95.318664721421 28.5651281566814 3.33688909773457 0.000964846372840804 -206.018824754327 44.3227432517285 -4.64815148250763 5.21905308398606e-06 DIS3L2 other 6.3516483829811e-10 0.0807335321561804 1 3.33688909773457 -4.64815148250763 1.06498863385777e-16 243.053272588047 28.1768979870664 8.62597695103313 5.3719453296997e-16 -27.6690326219393 78.3352832102144 -0.353212900854508 0.724202423573986 FANCD2 other 1.46829982949971e-12 1 7.95746261688416e-12 8.62597695103313 -0.353212900854508 4.4258862537913e-31 65.6422256390542 5.29529088349249 12.3963398958284 2.82019566490956e-28 -17.9314280222951 15.1106485970307 -1.18667494033437 0.236391289317125 TAMM41 essential 6.9473136525762e-27 1 4.43616778090274e-24 12.3963398958284 -1.18667494033437 7.94450164797865e-05 522.478039962869 125.224070147009 4.17234513579934 4.07273906287393e-05 -22.8130148028706 356.869254103597 -0.0639254139731749 0.949077093069296 VGLL4 other 0.595758178581919 1 0.396806966895807 4.17234513579934 -0.0639254139731749 4.04089038498971e-14 272.644368968949 38.5633129545611 7.07004528605217 1.32517518029185e-11 -165.941934700202 97.8301292297218 -1.69622524274237 0.0909958191556648 RAB5A other 5.21678948702171e-10 1 1.81721272473421e-07 7.07004528605217 -1.69622524274237 5.92495220476233e-17 378.651178810248 113.933301558678 3.32344603052897 0.00101205146009706 -926.537252263843 169.042430836695 -5.4810928101178 9.69857905347081e-08 RETREG2 other 8.22205617454869e-13 0.00153256946202946 1 3.32344603052897 -5.4810928101178 1.96438927582233e-16 317.490910943885 122.434370500613 2.59315182203918 0.0100286488621778 -1073.5562438491 182.534349959086 -5.88139297666293 1.19922281926738e-08 CTDSP1 other 2.69140974680418e-12 0.000190484552612431 1 2.59315182203918 -5.88139297666293 1.06101228462681e-14 331.233204011788 80.1120339156076 4.13462482254188 4.75032729550731e-05 -477.866991237576 119.236801059666 -4.00771395232629 7.93615090509589e-05 CNOT9 other 1.39109320637421e-10 1 0.459451656021467 4.13462482254188 -4.00771395232629 0.331941219516769 -8.11556625471496 16.9946113823906 -0.477537618961039 0.63336143997205 -36.899493297037 25.5630096146265 -1.44347218317846 0.150034007480754 MARCH4 other 1 1 1 -0.477537618961039 -1.44347218317846 2.92346091745241e-13 48.6479442835862 36.2332544121668 1.34263248148228 0.18052288503897 -318.377385558731 53.8101561194852 -5.91667834696065 9.96090400019431e-09 STK11IP other 3.67128222013674e-09 0.000158268803659087 1 1.34263248148228 -5.91667834696065 7.77945466822021e-15 34.5539415641894 47.5578624789447 0.726566329163501 0.46812341854061 -478.944881653812 70.6283784390534 -6.7811960608313 7.53952322667827e-11 GMPPA other 1.02330946705769e-10 1.20217697849385e-06 1 0.726566329163501 -6.7811960608313 0.301672057357879 -6.47616044745426 4.98103680700682 -1.30016313839405 0.194641657599813 -16.9042613714254 13.6247314298073 -1.24070418991478 0.215780208347858 GRIP2 other 1 1 1 -1.30016313839405 -1.24070418991478 4.32207321032424e-12 198.76566227072 28.0107958966568 7.09603764934232 1.10731861423368e-11 -8.80279247662612 76.6185005278909 -0.114891213166221 0.908615806038124 EAF1 other 5.19383537684664e-08 1 1.52145577595707e-07 7.09603764934232 -0.114891213166221 1.0580947115436e-12 79.113430819186 10.0950007279652 7.83689203706801 1.19951619841041e-13 80.095536317475 28.1722301124469 2.84306694918297 0.00482430091667181 CNTN4 other 1.30262039938132e-08 1 1.7191466155618e-09 7.83689203706801 2.84306694918297 4.12208372313959e-20 267.052172627846 27.2774189253169 9.79022881010151 1.47932981757849e-19 -34.1062927092199 89.5948654768164 -0.380672402684116 0.703746788100998 DYNC1LI1 other 6.03390615393173e-16 1 2.25938043038763e-15 9.79022881010151 -0.380672402684116 0.276271227876324 42.8169834937025 39.240074940247 1.09115447814262 0.27617767709959 -74.1972280893894 102.256726677998 -0.725597527906727 0.468713980772611 RBMS3 other 1 1 1 1.09115447814262 -0.725597527906727 0.000219794259775424 59.3800119094881 21.4691168139955 2.76583393830057 0.0060680470900821 -152.638166600503 68.3523703143143 -2.23310714608148 0.0263585054224377 OSBPL10 other 1 1 1 2.76583393830057 -2.23310714608148 2.37324589086824e-08 142.78320610687 26.2596206608028 5.43736743006344 1.20392184643309e-07 -59.5866059894307 69.0245044394932 -0.863267421813426 0.388750999986402 POMGNT2 other 0.000236351558271568 1 0.00141701601325175 5.43736743006344 -0.863267421813426 0.0016773842715632 -7.3419847328245 11.5768607941881 -0.634194784177623 0.526486707760513 -108.6784380505 30.4302598124203 -3.57139369563127 0.000419780467739301 ACKR2 other 1 1 1 -0.634194784177623 -3.57139369563127 0.969979297857401 -0.849618320610736 6.81955304452564 -0.124585631208304 0.900943627128303 -4.3440281855551 17.9254786456168 -0.242338197569821 0.808700741278059 FAM198A other 1 1 1 -0.124585631208304 -0.242338197569821 0.153561456650895 -63.1179648636477 186.422683696981 -0.338574488962095 0.735190554686145 -930.234866316972 495.40936467413 -1.87770949168242 0.0614869410797408 CSRNP1 other 1 1 1 -0.338574488962095 -1.87770949168242 1.01203564934822e-15 187.793065130894 24.5600170542451 7.64629213066587 3.54373306224803e-13 -55.6060721924167 65.2670705299283 -0.851977448059638 0.394973367320155 SLC25A38 other 1.36270600184738e-11 1 5.04556713402875e-09 7.64629213066587 -0.851977448059638 0.798568075167601 -38.5371093749999 62.1481469651792 -0.620084608421096 0.535719323509051 -87.7417724609367 194.096396511302 -0.452052557584847 0.651590082134198 ITGA9 other 1 1 1 -0.620084608421096 -0.452052557584847 2.41300511837925e-15 549.214453125 68.6382508989555 8.00157996353251 3.53099042593925e-14 -123.890112304685 214.365798706602 -0.577937866264998 0.563782458871789 GOLGA4 other 3.21870752740608e-11 1 5.10016257122666e-10 8.00157996353251 -0.577937866264998 3.64363079639333e-13 385.228515625 55.8084517323675 6.90269132482629 3.56695306151647e-11 -248.072045898436 174.296739405547 -1.42327416304232 0.155798479627045 CTDSPL other 4.56073266784554e-09 1 4.8303678359056e-07 6.90269132482629 -1.42327416304232 0.794755810826517 -13.6888419916077 20.906060779728 -0.654778637440937 0.513163598012329 -25.3424774852155 65.2535491722047 -0.388369334797966 0.698046534592673 STAC other 1 1 1 -0.654778637440937 -0.388369334797966 0.0126461867711824 163.173970237605 60.6437221309219 2.69069846810085 0.00757000906275426 -48.2610752555556 165.7479878547 -0.291171409561018 0.771141325724753 IQSEC1 other 1 1 1 2.69069846810085 -0.291171409561018 0.0343640719443865 37.6731891803008 14.5559197845246 2.58816960645481 0.0101654269919188 21.6588343975813 39.7834158406513 0.544418671446759 0.586597794518547 CAND2 other 1 1 1 2.58816960645481 0.544418671446759 2.1308526890191e-22 5243.00328866231 519.191303801521 10.098403517688 1.40129947808645e-20 -872.977104972262 1419.02427642847 -0.615195327855456 0.538938201466602 RPL32 essential 3.20075382417559e-18 1 2.15085456891489e-16 10.098403517688 -0.615195327855456 0.00151045141475514 226.509883305549 96.8743283188206 2.33818274909827 0.0201053657825087 -347.589445899816 207.577134363969 -1.67450739198638 0.095184517831047 PTPRG other 1 1 1 2.33818274909827 -1.67450739198638 0.000112476883087764 404.158578860991 93.9887432084233 4.30007429682037 2.37917073246483e-05 425.58179727361 223.924702421275 1.90055761008873 0.058413269088463 IL17RD other 0.828279767058291 1 0.236846446416874 4.30007429682037 1.90055761008873 6.54422438604859e-07 72.396123011281 16.7194357864084 4.33005778042663 2.0978707747214e-05 -45.7632307988051 35.7170802990675 -1.28127020505648 0.201190022959631 SHQ1 essential 0.00591532442254932 1 0.209724141348898 4.33005778042663 -1.28127020505648 0.0012418598668003 215.560166629845 63.1729434437402 3.41222293721071 0.000743113423288212 7.18581402116725 132.656954890466 0.0541683926568383 0.956841061243471 SLC25A26 essential 1 1 1 3.41222293721071 0.0541683926568383 1.26980574310822e-07 163.501355013551 53.9359325497214 3.03139942677038 0.00266982447850362 -370.918981481482 112.963293212707 -3.28353548247794 0.00115985015443484 UBA3 essential 0.00120771224227023 1 1 3.03139942677038 -3.28353548247794 1.34858672325195e-05 -234.86788617886 239.161177593367 -0.982048543757356 0.326951846224378 -2366.03038194444 500.898620871537 -4.72357136425665 3.7241141088283e-06 ARL6IP5 other 0.109208552848943 0.0577759062843622 1 -0.982048543757356 -4.72357136425665 2.63045153606934e-06 98.6493902439031 48.4300620766522 2.0369453602551 0.042627247878683 -358.009114583333 101.431810743814 -3.52955460380725 0.000488900001063623 TMF1 other 0.0225955786948356 1 1 2.0369453602551 -3.52955460380725 0.0366308329054008 728.602897087124 285.293088613957 2.55387503646479 0.0112028932875524 387.551337211527 599.087367529867 0.646902869625616 0.518244372449819 LRIG1 other 1 1 1 2.55387503646479 0.646902869625616 0.142631885625057 167.997940900224 107.764551390446 1.55893509259408 0.120170215074178 -174.217903330679 280.095712016873 -0.621994182189351 0.534464797145162 LIMD1 other 1 1 1 1.55893509259408 -0.621994182189351 0.145096979321144 12.3499321493893 6.90430283124819 1.78872978941404 0.07477110048302 -3.38634137707262 18.1273563256369 -0.186808341836556 0.851950164582771 ZNF660 other 1 1 1 1.78872978941404 -0.186808341836556 0.218008994037376 92.6904407848904 96.6337490761911 0.959193259818663 0.33833901950365 -418.008426826807 361.135330492732 -1.15748416599527 0.248120759136939 NFKBIZ other 1 1 1 0.959193259818663 -1.15748416599527 0.0870518882753268 -136.824222348704 118.74671400824 -1.15223586177896 0.250239583146972 -898.976220554124 417.63547510558 -2.15253797663347 0.0322379393125262 COL8A1 other 1 1 1 -1.15223586177896 -2.15253797663347 1.78932254053011e-07 306.047583323447 53.3180763421918 5.74003423077859 2.59318942543673e-08 271.701555335321 199.257933228819 1.36356706572536 0.173865462510225 NXPE3 other 0.00168554183317937 1 0.000315539289287141 5.74003423077859 1.36356706572536 0.620569950902321 -7.32736224484322 14.9692478099841 -0.489494351209554 0.624893654703573 -52.287731379679 55.3776771473801 -0.944202322544558 0.345919885102491 ADGRG7 other 1 1 1 -0.489494351209554 -0.944202322544558 0.473372343663251 1.92519595898607 3.04278535489839 0.632708434686927 0.527459529634614 -10.6742523805384 12.0408789357383 -0.88650109659822 0.376136474689964 MYH15 other 1 1 1 0.632708434686927 -0.88650109659822 1.47706380058468e-05 583.916819092413 125.550993611671 4.65083391453249 5.180830025951e-06 -97.8748768868962 467.446649033259 -0.209381920031546 0.834307998133807 PHLDB2 other 0.119272901897213 1 0.0544246194226152 4.65083391453249 -0.209381920031546 2.65369466555177e-16 215.257730162877 24.1667474959411 8.90718662902527 7.91387738135139e-17 26.2551752170249 89.9767083480926 0.291799685708123 0.770663856091443 ABHD10 other 3.62547765207682e-12 1 1.18296639096441e-12 8.90718662902527 0.291799685708123 0.0361432438990364 -68.6159742182734 59.561571539891 -1.1520175247948 0.25033289033835 447.425559285241 221.757361105334 2.01763565842901 0.0446184268198582 TAGLN3 other 1 1 1 -1.1520175247948 2.01763565842901 0.262354170476842 4.96850707498476 12.0895898341115 0.410973998552527 0.681416385107729 -68.3892377966315 45.9759036093854 -1.48750176565689 0.138044935465354 PLA1A other 1 1 1 0.410973998552527 -1.48750176565689 8.66383206045873e-13 116.372472945167 15.4043361791761 7.5545269586158 6.47584731390991e-13 -43.6689853923919 59.3470327331443 -0.73582424227932 0.462474055455265 RABL3 other 1.07041645106968e-08 1 9.16073361025696e-09 7.5545269586158 -0.73582424227932 0.0652433502401 26.1180972684365 16.4162045231454 1.59099487531435 0.11277653621217 -88.1585313544822 62.4297306314329 -1.4121241668484 0.159060650670892 ADPRH other 1 1 1 1.59099487531435 -1.4121241668484 6.89046696116343e-05 56.1231081982317 12.8652575563368 4.3623773525302 1.83032748404334e-05 -2.13868615093704 48.9636061065852 -0.0436790980280638 0.965192366620744 IGSF11 other 0.520472662463909 1 0.184002821970877 4.3623773525302 -0.0436790980280638 8.83630221736032e-21 285.447665516 29.6474110470879 9.62808068005108 4.61301854618773e-19 -220.018705010302 110.145692915666 -1.99752436238031 0.0467678214111245 ATG3 other 1.30459165937108e-16 1 7.02332073657082e-15 9.62808068005108 -1.99752436238031 0.127260109381458 12.4283330587185 54.6574842639873 0.22738575011414 0.820293991976711 -402.87707267378 208.041396487979 -1.93652359326025 0.0538355074922488 BOC other 1 1 1 0.22738575011414 -1.93652359326025 8.62454549716221e-09 482.376741367595 77.7229006176972 6.20636565972114 2.006218209889e-09 -37.6447599590124 389.76135351488 -0.096584126721469 0.923127527137814 SRPRB essential 8.82118513449751e-05 1 2.56314438495419e-05 6.20636565972114 -0.096584126721469 0.415318387333641 31.3451889600721 24.582167252522 1.27511901770404 0.203351201160244 -17.811016783838 120.591365677335 -0.147697280678409 0.882690701822287 TMEM108 other 1 1 1 1.27511901770404 -0.147697280678409 0.714835050778312 0.717030974223692 6.68782148604588 0.107214430845646 0.91469968609875 -32.6926162260711 41.0928936052281 -0.79557834354872 0.426986520486148 AGTR1 other 1 1 1 0.107214430845646 -0.79557834354872 2.53605312714956e-08 63.0206122903243 10.6274288825629 5.92999614363228 9.34397580773747e-09 -79.920758399872 70.5980945806073 -1.13205262655666 0.258627966197282 MED12L other 0.000252134401901209 1 0.0001161736512176 5.92999614363228 -1.13205262655666 4.2112131618452e-22 529.566648287269 48.5924739578185 10.8981207408161 3.67727317703929e-23 112.759399338342 317.389772313283 0.355271055259593 0.722663912513027 EIF2A other 6.30923955907648e-18 1 5.71448251711906e-19 10.8981207408161 0.355271055259593 0.497421744662431 -8.79420366923707 33.1463735273082 -0.265314202834039 0.79096987579174 -149.597447487371 126.538596661054 -1.18222780586133 0.238155420091424 ALDH1L1 other 1 1 1 -0.265314202834039 -1.18222780586133 1.83871438108519e-12 219.987114350702 28.9014599813343 7.61162635011443 4.58728866012509e-13 10.8959922824586 109.476506801939 0.0995281325715958 0.920793083139941 OSBPL11 other 2.24451864499069e-08 1 6.51394989737763e-09 7.61162635011443 0.0995281325715958 0.0052656670309767 18.9156620138158 6.0797795976957 3.11124140437345 0.00206279605950802 46.3735786794954 33.5072203422278 1.38398763627231 0.167505186841018 TRPC1 other 1 1 1 3.11124140437345 1.38398763627231 2.55838751732054e-05 151.101253326545 33.4587088732631 4.51605152783676 9.53367517810522e-06 469.590264964977 341.738572126623 1.37412134089148 0.170578374607894 NCEH1 other 0.201959110617283 1 0.0980633828819902 4.51605152783676 1.37412134089148 9.04433271082312e-07 9.69708101604453 2.20133672560806 4.40508755577409 1.52603761682261e-05 0.691540855749008 3.69623167570026 0.187093482341849 0.851727848798693 FAM86B2 other 0.00807930241057829 1 0.154343444565439 4.40508755577409 0.187093482341849 2.36879939472182e-13 331.490511989782 43.3645736233314 7.64427006406517 3.86989128863349e-13 -685.18663119878 363.695853909696 -1.8839550240485 0.060665775042169 LPP other 2.98421347747055e-09 1 5.50608132546773e-09 7.64427006406517 -1.8839550240485 1.63248670148075e-09 118.454583304816 18.0122720069071 6.5763265877504 2.48619057853882e-10 12.0853567961225 138.711366922832 0.0871259296496292 0.930635994651593 TMEM44 other 1.74365904585159e-05 1 3.28003123026627e-06 6.5763265877504 0.0871259296496292 0.00846977394898315 45.2172851043945 23.1461942883042 1.95355160944289 0.0517755077793854 -91.9592687779214 55.1572973364219 -1.66721854076773 0.0966176681145009 AMT other 1 1 1 1.95355160944289 -1.66721854076773 0.40195662919761 41.8410186699517 56.8470741427217 0.736027654913331 0.462345801239956 -113.271737360435 135.466372231227 -0.836161295934698 0.403795432333456 TCTA other 1 1 1 0.736027654913331 -0.836161295934698 0.0073827756547124 48.3875554894755 27.9340910083943 1.7322044048233 0.0843666425435723 -129.405666121507 66.5668379164704 -1.94399599217688 0.052923198281717 NICN1 other 1 1 1 1.7322044048233 -1.94399599217688 6.83056706391951e-05 -25.7117294870044 52.9076261224114 -0.485973977126013 0.62737688426059 -567.254411030978 130.133493029658 -4.35901932565276 1.85446451050745e-05 UCN2 other 0.516391024592172 0.283491989721274 1 -0.485973977126013 -4.35901932565276 5.76510628931025e-11 324.254966500324 50.0283565023809 6.48142351997696 4.2742399000605e-10 -88.8385038029623 118.249855712884 -0.751277904462447 0.453137324137555 DCAF1 other 6.63160176459358e-07 1 5.5954074531692e-06 6.48142351997696 -0.751277904462447 0.00015462908026411 99.528275625242 83.8958788474603 1.18633092581585 0.236530651688482 -686.566582887036 198.301048889057 -3.46224382943707 0.000622305240755251 MANF other 1 1 1 1.18633092581585 -3.46224382943707 0.0040660636844644 31.7404192270573 11.7132378894381 2.70979036938008 0.00716347765447061 109.974183851386 45.1673034962732 2.4348184491567 0.0155472993074835 STXBP5L other 1 1 1 2.70979036938008 2.4348184491567 0.0006140609454754 15.6465657106972 4.75573900135425 3.29003877341495 0.00113489689988076 -28.2694272628473 18.6513707856786 -1.51567558157998 0.130771237501134 EAF2 other 1 1 1 3.29003877341495 -1.51567558157998 0.000278588853258032 58.2371441423102 14.6703021137381 3.96973039074457 9.22282026929846e-05 -21.7027483617648 57.7174891959563 -0.376016847997007 0.707198558120871 ILDR1 other 1 1 0.868236300151757 3.96973039074457 -0.376016847997007 0.0982446229688266 17.1775835719306 9.38154667744772 1.8309969733694 0.0682195445017265 97.3662702243065 72.3553950800869 1.34566703860211 0.179555797509738 TM4SF19 other 1 1 1 1.8309969733694 1.34566703860211 0.827283371145672 -66.6831420617732 342.728035927978 -0.194565763729309 0.845879223413392 -1595.18331627844 2649.28517509748 -0.602118386979516 0.547600634386102 MUC4 other 1 1 1 -0.194565763729309 -0.602118386979516 0.0446068461390062 55.1877643355966 139.849133173313 0.394623571010649 0.69343457613033 -323.588806924361 202.105635565523 -1.60108750069689 0.110535596942956 SLIT2 other 1 1 1 0.394623571010649 -1.60108750069689 6.20749337764582e-47 473.009324369117 26.2455905224679 18.0224302426798 4.13403028955468e-48 228.067462871033 312.493775019879 0.729830419362832 0.466131273185033 EIF2B5 essential 9.87860496118557e-43 1 6.58220302702896e-44 18.0224302426798 0.729830419362832 2.84911140507746e-08 3.4395487660069 0.568619351595832 6.04894778264897 4.92498551568374e-09 7.25535376212842 5.22946243944268 1.38739953602222 0.16648121689798 AHSG other 0.000282688833611786 1 6.19513928017857e-05 6.04894778264897 1.38739953602222 1.42018000786861e-16 162.463400054296 17.9338600348811 9.05903133727521 2.82696375611882e-17 313.926161280293 194.995639590873 1.60991374955333 0.108593890222463 ECE2 other 1.95232145681698e-12 1 4.24242450880751e-13 9.05903133727521 1.60991374955333 1.9415508449468e-05 22.4295855189529 4.98737687653772 4.49727102526965 1.02741460440282e-05 90.6226453767831 55.3563993023622 1.63707622820251 0.102792588786526 VWA5B2 other 0.155149328019699 1 0.105412738411729 4.49727102526965 1.63707622820251 9.55246894808013e-29 209.962109375001 19.2466418362449 10.9090256451702 3.82334604768512e-23 -83.55390625 52.7019857308374 -1.58540337885429 0.114062781237053 DGKQ other 1.48875228555829e-24 1 5.94071508889314e-19 10.9090256451702 -1.58540337885429 1.84943204737465e-33 493.091899012167 37.9465134929292 12.9943927287035 1.37411672393116e-29 -18.8008910852991 81.4380808708928 -0.23086117556116 0.81761933371687 FIP1L1 essential 2.91636939550509e-29 1 2.16547054524311e-25 12.9943927287035 -0.23086117556116 2.07366405358858e-53 59.3993902708925 3.07491559987363 19.3174050934385 1.4715983482149e-52 32.3856165899434 8.4198666680071 3.84633366143418 0.000150128030813935 SLC26A1 other 3.30334683736661e-49 1 2.34440332854116e-48 19.3174050934385 3.84633366143418 2.33892511097142e-13 225.976535308013 35.1091532065664 6.43639947618415 5.50308208475921e-10 18.0471754164361 55.9675023765611 0.322458116765885 0.747353375762625 LYAR other 2.94681174731289e-09 1 7.17491842210906e-06 6.43639947618415 0.322458116765885 3.26371489184774e-17 90.6967375037407 18.8496257345264 4.81159354467255 2.49812994518414e-06 -124.336366357378 32.1137198564084 -3.87175222656638 0.000135714962529943 CENPC essential 4.55745147497618e-13 1 0.0269198482893043 4.81159354467255 -3.87175222656638 0.474969134161339 7.77434911674529 17.1686341223668 0.452822808228937 0.651042700953449 -18.5848216458221 28.0876649428133 -0.661672007397588 0.508749940781676 EPHA5 other 1 1 1 0.452822808228937 -0.661672007397588 0.212491979750447 -11.241036546246 7.7444721577585 -1.4514916339372 0.147867351150456 -21.3909412959617 12.7215460630769 -1.68147339874411 0.0938904823230634 CORIN other 1 1 1 -1.4514916339372 -1.68147339874411 2.55105649356637e-07 145.523768994392 53.5474911315509 2.71765802503952 0.00702169166928621 -200.764469002193 87.9810276046453 -2.28190638900417 0.0233128034041671 ATP10D other 0.00237911528589999 1 1 2.71765802503952 -2.28190638900417 1.39987485553391e-07 32.7713662883881 103.743937668515 0.315887048678447 0.752352858304278 -706.471861575944 165.894590989915 -4.25855874721612 2.91815544765778e-05 OCIAD2 other 0.00132806127544502 0.443647172707412 1 0.315887048678447 -4.25855874721612 0.121051270894183 32.591278331697 24.8522338807675 1.3114023668077 0.190920195357102 -19.5179436479337 40.8767995598887 -0.477482186914803 0.633434318142133 SLC10A4 other 1 1 1 1.3114023668077 -0.477482186914803 0.364742612522278 -11.8613241048485 12.2510135475951 -0.968191248729533 0.333812131678172 -26.5392380325084 18.7140890793808 -1.41814212382634 0.157298147871082 SLC10A6 other 1 1 1 -0.968191248729533 -1.41814212382634 4.17659253058454e-05 139.980028773185 111.152210220473 1.25935443384825 0.208993977938074 -460.801537560194 168.731140208191 -2.73098099729325 0.00673204291058693 SCD5 other 0.322432943361126 1 1 1.25935443384825 -2.73098099729325 0.00184521738018944 273.98954335396 122.723059881004 2.2325840279702 0.0263934523824831 -162.398216321592 186.122206928225 -0.872535411017439 0.383688774912118 PLAC8 other 1 1 1 2.2325840279702 -0.872535411017439 1.39395120157576e-15 348.749417720628 60.4547991646971 5.76876315097052 2.18296145717384e-08 -165.797021805814 91.6303580452798 -1.80941148046027 0.0714991321239243 ENOPH1 other 1.87082190763482e-11 1 0.000266408616233496 5.76876315097052 -1.80941148046027 0.233759093439514 10.1880900011405 6.99991355765662 1.45545940206599 0.146699531004139 -0.933168543823994 15.1794347809649 -0.0614758426311233 0.95102556665521 GC other 1 1 1 1.45545940206599 -0.0614758426311233 4.31330915068005e-08 32.2171490673799 11.5589085796336 2.78721376204545 0.00569232459256511 -40.1987381741186 17.0471970455525 -2.35808491370763 0.0190801319034192 TRMT10A other 0.000422704296766645 1 1 2.78721376204545 -2.35808491370763 4.66880300061927e-12 129.820898204411 29.8466269376745 4.34960032420084 1.93525364412175e-05 -100.059771966956 45.6677396915757 -2.19103841448527 0.0293037519658476 KLHL8 other 5.59882855834263e-08 1 0.19408658796897 4.34960032420084 -2.19103841448527 0.011231412690757 243.622677991851 83.6341665451622 2.91295636766219 0.00387742468533851 152.821339560929 129.562061619205 1.17952228955792 0.239220903695911 SNCA other 1 1 1 2.91295636766219 1.17952228955792 7.31495387373508e-13 350.591430149849 83.1292397101824 4.21742615922068 3.36821944968615e-05 -334.60789059018 128.779853050516 -2.59829377549395 0.00987955133988365 PYURF other 9.06395934494514e-09 1 0.330590738986696 4.21742615922068 -2.59829377549395 1.31070768673487e-15 89.9303516656992 24.5641287655473 3.66104381409334 0.000302342192151975 -145.822860012518 36.0427214749653 -4.04583377850101 6.81796183410602e-05 TBCK other 1.76014935251625e-11 1 1 3.66104381409334 -4.04583377850101 3.6934648243622e-08 163.221820316594 81.2893270796997 2.00791206152518 0.0456524062063269 -375.162072136937 115.694096554814 -3.24270713293648 0.00133337513719496 CAMK2D other 0.00036332613477251 1 1 2.00791206152518 -3.24270713293648 8.34576103257161e-07 139.486789240967 47.9945558898988 2.90630440587793 0.00395937638246353 -122.899435215707 70.1757023202995 -1.75131037028691 0.0810237752022085 CISD2 other 0.00747279442856462 1 1 2.90630440587793 -1.75131037028691 0.848661199126555 -2.78957271153934 10.5884620674985 -0.263454002456315 0.792400877424484 -8.82480822302255 15.7205228342101 -0.561355898661241 0.57501884095407 DDIT4L other 1 1 1 -0.263454002456315 -0.561355898661241 0.307535876979175 0.461749104107194 49.8000594857569 0.00927205928818733 0.99260894562931 -85.3062022174542 71.0485923401064 -1.20067406556202 0.230933873360963 ANK2 other 1 1 1 0.00927205928818733 -1.20067406556202 1.47584047212289e-12 11.5647490353379 31.1233698352472 0.371577663233652 0.710499830772404 -291.941641374472 48.2952334891527 -6.04493694890291 4.97159702824169e-09 TIFA other 1.80775699430333e-08 7.90533643460712e-05 1 0.371577663233652 -6.04493694890291 6.00221805314381e-17 84.1329112449345 14.4734577515975 5.81291027264363 1.72787532497871e-08 -54.6361828183617 21.8331885552345 -2.50243718090653 0.0129257535787691 SPATA5 other 8.32807754873704e-13 1 0.000212113974894386 5.81291027264363 -2.50243718090653 4.27668798902883e-13 579.830245089517 80.6846386830552 7.18637716613199 6.55765507499875e-12 169.90557861116 120.663085014577 1.40809907678587 0.160256368604592 CCNA2 essential 5.33944495430249e-09 1 9.05808895509577e-08 7.18637716613199 1.40809907678587 4.28707666378133e-21 88.7948987061548 20.0113749432019 4.437221278307 1.33023791020726e-05 -154.381542537241 29.7929361420794 -5.18181698510718 4.3174919208689e-07 METTL14 essential 6.35387632339031e-17 0.00678752904879799 0.135245288330772 4.437221278307 -5.18181698510718 6.78588261740695e-15 144.567804913096 47.2772423461123 3.05787304290568 0.00245295284038294 -330.458128947558 70.5535378074472 -4.6837924676355 4.4665672194992e-06 USP53 other 8.94175752495714e-11 0.0692049924989207 1 3.05787304290568 -4.6837924676355 4.75992759899615e-08 300.543180943054 119.405669227212 2.51699255896438 0.012415783443558 -487.124827081323 177.278803768634 -2.74778945212801 0.00640399526062372 SETD7 other 0.000464949727869944 1 1 2.51699255896438 -2.74778945212801 1.19775361285628e-25 73.6391010704144 9.43561677990566 7.8043759923822 1.30557079298208e-13 -37.2533186485107 13.7169295456869 -2.71586425551223 0.00703526795067169 NAF1 essential 1.84226483193424e-21 1 1.87009960386753e-09 7.8043759923822 -2.71586425551223 0.00215117801582424 45.2588648714194 32.4617349488594 1.39422199530372 0.164392580341729 -83.2551445319385 47.1531459466624 -1.76563287264254 0.0785835117683923 MARCH1 other 1 1 1 1.39422199530372 -1.76563287264254 0.0249227335990628 -1279.78367584619 557.396804560662 -2.29600109899251 0.0224337025190741 -2113.81341760891 826.286463498016 -2.55820893962156 0.0110614922016893 SFRP2 other 1 1 1 -2.29600109899251 -2.55820893962156 0.000280812530035024 1611.43201172692 427.342587782477 3.77082008158559 0.000199924711065771 645.057945344119 627.811812837798 1.02747022619464 0.305118686491691 RPS3A essential 1 1 1 3.77082008158559 1.02747022619464 0.00025448056960205 21.5341412418498 6.01228055131321 3.58169268018377 0.00040404779098213 4.11489311948052 8.91262022612087 0.461692859684596 0.644669266185578 RNF175 other 1 1 1 3.58169268018377 0.461692859684596 0.000544005061356386 128.154275773878 66.3142223708772 1.93253077834716 0.0543283800486649 -159.223561397648 97.7952656398529 -1.62813159058246 0.104650450302835 PDGFC other 1 1 1 1.93253077834716 -1.62813159058246 2.990728171284e-11 106.043458716628 28.6859585025257 3.6967026466029 0.000264675591650825 -114.257402992503 41.6897117089648 -2.74066186377427 0.00654219053620268 CBR4 other 3.4794131544718e-07 1 1 3.6967026466029 -2.74066186377427 0.528228100475478 8.01749832688569 10.0741352050968 0.795849783992318 0.426818485092628 16.7196480746944 14.9152432509226 1.12097723070391 0.263293586201412 GLRA3 other 1 1 1 0.795849783992318 1.12097723070391 4.09421914355798e-11 -4.62869241249889 34.2075416799449 -0.135312044805973 0.892465983534739 -300.236026073733 52.7130670164074 -5.69566604766674 3.20567586113122e-08 CYP4V2 other 4.73864923675401e-07 0.000508291964540966 1 -0.135312044805973 -5.69566604766674 0.155125368727872 2.04057297226818 3.43738682151757 0.593640773710562 0.553251243010873 -38.6460294241483 21.5801128768807 -1.79081683421363 0.0744469853564816 ROPN1L other 1 1 1 0.593640773710562 -1.79081683421363 7.7313652722417e-17 422.684503403218 45.7050074157417 9.24810053214513 7.72339027283981e-18 231.721429299271 269.675198215314 0.859261180979128 0.390970122345335 NDUFS6 other 1.0701755809837e-12 1 1.16515065656061e-13 9.24810053214513 0.859261180979128 2.08664045398373e-27 984.064101832764 79.7957038223213 12.3322942802027 5.35663482803102e-28 -461.355318594096 500.962034530519 -0.920938687552359 0.357907604390244 MARCH6 other 3.23533602390177e-23 1 8.42062994966476e-24 12.3322942802027 -0.920938687552359 4.78492468534531e-05 84.4783967189688 18.5876818569293 4.54485919057606 8.35059331677291e-06 53.5764078142607 107.820299461808 0.496904646728776 0.619666724123277 NKD2 other 0.366955874119132 1 0.0863033819288481 4.54485919057606 0.496904646728776 1.16001334520823e-06 17.9159131821391 3.38957443150229 5.28559367678457 2.65520432751129e-07 36.5700630657213 23.1806703664496 1.57761024541597 0.11587105269283 CDH18 other 0.010283518305271 1 0.00306304371221703 5.28559367678457 1.57761024541597 0.578802199531847 -2.17960919539583 6.73508114905256 -0.323620331687086 0.746475092063287 -40.5675202320479 39.6612335877025 -1.02285069228473 0.307290634320993 ADAMTS16 other 1 1 1 -0.323620331687086 -1.02285069228473 5.43146942844878e-08 287.793434928848 48.2302561465856 5.96707249603156 7.53159055260646e-09 148.210772199871 278.763416052491 0.531672248455884 0.595388561027689 SRD5A1 other 0.000528970807636627 1 9.39791869154234e-05 5.96707249603156 0.531672248455884 2.15483619150365e-15 891.089128321108 103.035280814817 8.64838840904065 5.40362246035732e-16 1805.54326689353 704.479479048498 2.56294657345048 0.0109401851453579 MYO10 other 2.87864566822973e-11 1 8.00384558828126e-12 8.64838840904065 2.56294657345048 0.228210210355884 12.1918198316702 20.1163500438792 0.6060652059184 0.545004294936 -204.157379057216 133.908886257721 -1.52459918652668 0.128583939472504 FAM105A other 1 1 1 0.6060652059184 -1.52459918652668 9.48982732943061e-17 4365.67971893019 472.084949618632 9.24765706353686 9.53249210903873e-18 4061.08171412119 3062.99695373516 1.32585235162213 0.18607506035388 RPL37 essential 1.3099757645546e-12 1 1.43645123591105e-13 9.24765706353686 1.32585235162213 2.09834935854242e-13 312.751270783816 38.9166726529152 8.03643398738477 2.96586323299927e-14 152.644358089955 261.040028881838 0.584754601598098 0.559204691651203 SKP2 other 2.64832672541639e-09 1 4.29101092550334e-10 8.03643398738477 0.584754601598098 3.94148334436855e-11 797.25580751831 112.847458363639 7.06489821817024 1.43854856251341e-11 -268.228316668584 748.118144564974 -0.358537376238291 0.720228833085689 OSMR other 4.56581430611653e-07 1 1.97023611121836e-07 7.06489821817024 -0.358537376238291 0.14943689068476 32.2372348733383 17.4981275718889 1.84232482823637 0.06652406388395 -37.0737377213254 114.732449805169 -0.323132102419862 0.746845311942337 UGT3A1 other 1 1 1 1.84232482823637 -0.323132102419862 0.000347209594225799 577.602245205212 142.680296489278 4.04822711626913 6.73972802889323e-05 531.160431594 257.523058095207 2.06257426237004 0.0401059814428614 PLK2 other 1 1 0.643307040357859 4.04822711626913 2.06257426237004 0.313351914619449 37.7717490134748 39.2985747043295 0.961148064469462 0.337334507348404 -32.5026686185009 71.2261974966894 -0.45633025152033 0.648518011016193 GZMA other 1 1 1 0.961148064469462 -0.45633025152033 0.133043423337846 29.9293471010454 243.785710583327 0.122769078751297 0.902380621801503 -635.583473411775 377.047614707275 -1.68568490721051 0.0930032673134356 PIK3R1 other 1 1 1 0.122769078751297 -1.68568490721051 0.749096837938366 24.3127635960042 32.2941356056983 0.752853827482976 0.452188837636414 23.5325900514576 50.6377574779168 0.464724174677763 0.642500778739293 HAPLN1 other 1 1 1 0.752853827482976 0.464724174677763 0.222015514623674 -59.1653148917159 80.3916017443966 -0.735963876921257 0.4623845513433 -218.813844046946 126.170870132589 -1.73426595074601 0.0839997075105094 LHFPL2 other 1 1 1 -0.735963876921257 -1.73426595074601 0.000422207999328622 148.195355374784 60.8883350193595 2.43388746510584 0.0155792774254221 -148.935740395046 95.5614024801123 -1.55853447657428 0.120265076110142 SSBP2 other 1 1 1 2.43388746510584 -1.55853447657428 0.526629505913669 -13.6627590668203 42.3167618414814 -0.322868727952317 0.747043630640223 -73.2865471856158 66.1838476979139 -1.10731771776282 0.2691384663404 IQGAP2 other 1 1 1 -0.322868727952317 -1.10731771776282 4.37464056876702e-13 109.270265826253 39.8995846366521 2.73863166299423 0.00657547373452831 -324.765363417679 63.0794146508647 -5.14851580686358 5.03053064570534e-07 RASA1 other 5.45823903765061e-09 0.00790195753827395 1 2.73863166299423 -5.14851580686358 0.604161760843476 27.3776684720765 29.9164757103422 0.915136820832542 0.360927406859555 43.1129844913038 52.8076890993053 0.816414905227713 0.414974687146907 LIX1 other 1 1 1 0.915136820832542 0.816414905227713 5.33009314829847e-12 21.5972589275963 5.26006065426221 4.10589541588197 5.32553840114441e-05 -31.6804157111136 8.67253854541875 -3.6529576138752 0.0003107464838091 GIN1 other 6.38012149851327e-08 1 0.513168880334275 4.10589541588197 -3.6529576138752 1.3242062671166e-07 123.161395653598 32.5449621947103 3.78434594321379 0.000189458864943383 -111.467740526374 53.6585902035401 -2.07735127038465 0.0387040137454832 PPIP5K2 other 0.00125786353313406 1 1 3.78434594321379 -2.07735127038465 0.0203772145287314 686.681653379928 416.956834188485 1.64688907118264 0.100731419032254 -843.986978996033 687.458653798092 -1.22769125726056 0.220620394415873 PAM other 1 1 1 1.64688907118264 -1.22769125726056 2.63294924962106e-06 136.87167169328 34.3104524356508 3.98921209068819 8.53596535971329e-05 -49.1043349699516 53.772326822991 -0.913189699445115 0.36195447605289 BDP1 essential 0.0226144011049952 1 0.805880489610532 3.98921209068819 -0.913189699445115 6.31877736756468e-05 87.8000978553369 24.8200316125806 3.5374692194523 0.000475666569301725 -24.6626233384982 38.5499736036181 -0.639757204300225 0.522874935798411 GTF2H2 essential 0.479532014424483 1 1 3.5374692194523 -0.639757204300225 2.66276418023654e-08 136.273210775812 51.365631808678 2.65300369093852 0.00844698042571351 -274.171233668633 79.4439054899993 -3.45112985039673 0.000647024150389658 SLC30A5 other 0.000264465738381093 1 1 2.65300369093852 -3.45112985039673 1.12038928258671e-16 1934.09424669799 320.764793365167 6.0296338211163 5.33946402531394e-09 -1559.12888658243 498.4984808959 -3.12765022629631 0.0019534165390815 BTF3 other 1.54378439247623e-12 1 6.70690076219684e-05 6.0296338211163 -3.12765022629631 8.48719298716248e-10 24.5680381856479 30.3608024500066 0.809202530997087 0.419103342942578 -278.607161586802 50.4544868191254 -5.5219501604601 7.8056738833757e-08 FBXL17 other 9.20860439107129e-06 0.0012345453813947 1 0.809202530997087 -5.5219501604601 7.92288241758508e-05 2.95495933221259 0.943576436839997 3.1316586731528 0.00192715492638799 -1.95733040512306 1.6431502261365 -1.19120599808168 0.234607345674772 SPATA9 other 0.594216181318881 1 1 3.1316586731528 -1.19120599808168 0.0169884659481417 149.314131265699 81.515943838433 1.83171689162606 0.0680831219045346 -146.181973717738 134.39962226142 -1.08766655187021 0.277701659343708 TSLP other 1 1 1 1.83171689162606 -1.08766655187021 3.94140611050298e-06 33.0525277435265 49.3804944326066 0.669343799071025 0.503843940729055 -335.699603183499 81.3339251092008 -4.12742410664162 4.88239241052779e-05 TNFAIP8 other 0.0334112995987337 0.737241253989696 1 0.669343799071025 -4.12742410664162 5.82686914711239e-09 77.7858892128284 40.4287744853933 1.92402293175946 0.0553912224544995 -294.88235927338 66.1284531019189 -4.45923570628364 1.20266987340823e-05 FEM1C other 6.02090388971123e-05 0.184790226049174 1 1.92402293175946 -4.45923570628364 0.000119046068637266 151.376769420467 48.3161541473257 3.13304674372238 0.00191909533815252 -89.2173585920873 79.5808650386525 -1.12109058564209 0.263238106304393 COMMD10 other 0.873202913454344 1 1 3.13304674372238 -1.12109058564209 7.08674098382459e-11 146.044724770641 33.6663598153635 4.3380016601615 2.0257766771858e-05 -161.330604028999 55.5016423714738 -2.9067717122533 0.0039513925965094 ATG12 other 8.1164444487743e-07 1 0.202638441018896 4.3380016601615 -2.9067717122533 0.735626597267626 31.2660061267997 44.2621942166679 0.706381748129102 0.480553183535189 45.5668440406192 70.7912717013951 0.643678845505485 0.520324068220902 MEGF10 other 1 1 1 0.706381748129102 0.643678845505485 8.17191422538544e-07 182.921944753401 51.1537074473035 3.57592741331291 0.000412894370229065 -163.505189462617 85.5301448269042 -1.91166739859401 0.0569695720219912 YIPF5 other 0.00732366952879043 1 1 3.57592741331291 -1.91166739859401 0.000786016687877412 20.0264928920306 52.6732897067582 0.380202053137782 0.704092155494737 -278.078620759325 87.4721677143537 -3.17905258353045 0.00164832456478838 ARHGAP26 other 1 1 1 0.380202053137782 -3.17905258353045 0.181023048831733 1628.28088873711 877.979602849118 1.85457712622616 0.0647348439480378 1311.29269461278 1460.48043172399 0.897850232108142 0.37005654104922 CXCL14 other 1 1 1 1.85457712622616 0.897850232108142 0.316751912674725 4.37307594403654 7.04864148674259 0.62041401201375 0.535502809917925 17.7557493840505 11.7159998418227 1.5155129415987 0.130799529322743 SLC25A48 other 1 1 1 0.62041401201375 1.5155129415987 1.0991456850322e-08 375.592102322847 66.9977951464732 5.60603675839947 5.06278310089605e-08 35.9570420464584 108.979369203882 0.329943569219868 0.741695635268552 DDX46 essential 0.000111717167426673 1 0.000608090878248624 5.60603675839947 0.329943569219868 6.33271945201158e-06 249.218713856117 191.996008262037 1.29804112133406 0.19536878254333 -1129.99597758758 313.618875430442 -3.60308663194032 0.000373584816000488 RNF145 other 0.0526692276823803 1 1 1.29804112133406 -3.60308663194032 0.0262787921047202 -0.555285681239913 4.83776358237621 -0.1147814835894 0.908702700487635 -19.2139846300152 7.90232040778928 -2.43143578575681 0.0156828003325223 C1QTNF2 other 1 1 1 -0.1147814835894 -2.43143578575681 0.688191921272331 4.03921472005677 10.6411009744078 0.379586165921292 0.704547734951747 -8.49573424528822 17.2585352473606 -0.492262762947249 0.622929225679976 GABRB2 other 1 1 1 0.379586165921292 -0.492262762947249 1.60920738471052e-12 130.033695420695 26.8477102445587 4.84338121337735 2.14523762091907e-06 -137.391768055788 44.7587135108227 -3.06960940739654 0.00236009453581399 FBXO38 other 1.96870431445485e-08 1 0.0232157615335862 4.84338121337735 -3.06960940739654 7.72166065315123e-05 81.5136313856233 23.0216410943996 3.54073938740418 0.000468975934767733 -26.0031401130053 38.1402734794719 -0.68177644628062 0.495958300026787 PCYOX1L other 0.579742281838594 1 1 3.54073938740418 -0.68177644628062 2.81873729932664e-05 409.523083935345 173.210611545593 2.36430713038357 0.0187639748241423 -704.690239073113 289.050439460064 -2.43794903197327 0.0154091065587737 TNIP1 other 0.221440002235101 1 1 2.36430713038357 -2.43794903197327 2.90955997921514e-13 1208.62700575383 167.278353979658 7.22524449218818 5.00818467355741e-12 92.6333640465643 279.150805476194 0.331839859421306 0.740264800484875 G3BP1 other 3.6541163778963e-09 1 6.93984150214851e-08 7.22524449218818 0.331839859421306 0.0754746876155213 34.9551701153706 17.5658513475657 1.9899502405965 0.0475937924545552 -1.55814929898703 29.3135449739321 -0.0531545843524779 0.95764761580506 ZNF300 other 1 1 1 1.9899502405965 -0.0531545843524779 2.62991523238415e-06 42.8466890744656 19.1973725681739 2.2319038150824 0.0264329390457108 -102.53261374268 32.3974082652056 -3.16484000520495 0.00172727960201314 N4BP3 other 0.0225936017614122 1 1 2.2319038150824 -3.16484000520495 4.40254327456427e-12 389.116555667211 68.0065040856042 5.72175501298235 2.76833411660338e-08 -212.669165944766 114.767501111235 -1.85304344771472 0.0649551200430282 NHP2 essential 5.28657396409678e-08 1 0.000336380278508477 5.72175501298235 -1.85304344771472 5.28914850017136e-21 416.134739249456 56.8891167250901 7.31483916792693 2.87332302680092e-12 -332.217806576804 96.0058431873731 -3.46039152979907 0.000625750760601849 RMND5B other 7.83058435450369e-17 1 4.00684896087389e-08 7.31483916792693 -3.46039152979907 1.742142749384e-07 369.529251809683 68.1764030291842 5.42019284372482 1.31308163972653e-07 106.752296407867 110.592493664478 0.965276149136656 0.335263941119472 BOD1 other 0.00164249218411923 1 0.0015427396185147 5.42019284372482 0.965276149136656 0.120753173766069 581.834817156617 288.228885942135 2.01865546978323 0.0445006413277333 261.803190639757 479.255598211236 0.546270490354012 0.585326167325387 CPLX2 other 1 1 1 2.01865546978323 0.546270490354012 6.5992882006585e-06 1401.97761045012 292.602950715237 4.79139942718668 2.72214004561456e-06 502.655148259982 471.001825067638 1.0672042474311 0.286822442490061 TENM2 other 0.0548004892182682 1 0.0292521169301741 4.79139942718668 1.0672042474311 0.2313336711482 -6.47905437382281 12.2194672539353 -0.530223964693405 0.596387650500034 -33.3862132709098 19.8038729122885 -1.68584263385135 0.0929686377687621 KCNMB1 other 1 1 1 -0.530223964693405 -1.68584263385135 0.00548270915819215 64.7564828693599 19.879471271395 3.25745498888289 0.00126905538860596 47.8548608372589 35.6129086560041 1.34375041644319 0.180165662699724 FAM50B other 1 1 1 3.25745498888289 1.34375041644319 0.0116556672242738 5.08638235607881 3.16737612960975 1.60586622742071 0.109489768349952 -9.72667384006309 5.70103667737815 -1.70612370880875 0.089152242581876 MYLK4 other 1 1 1 1.60586622742071 -1.70612370880875 1.6059550253905e-17 97.3853731034771 12.0039113579 8.11280341881113 1.79291312417763e-14 -29.137166555963 21.6078792756913 -1.34845100642255 0.178651820567203 FARS2 other 2.25572442866349e-13 1 2.60295127368108e-10 8.11280341881113 -1.34845100642255 0.787027739911381 25.059545730219 36.5467994752028 0.685683728536121 0.493496561930624 11.0027357340067 69.3747112796793 0.15859865260772 0.874102778772498 GFOD1 other 1 1 1 0.685683728536121 0.15859865260772 0.000113440354338711 417.370569754845 97.5001967125094 4.28071515573974 2.59666956623662e-05 134.257398917684 181.650280270884 0.739098220588892 0.460494188097543 CDKAL1 other 0.83503444828725 1 0.257745421144647 4.28071515573974 0.739098220588892 0.19423312151633 9.41016067686098 5.1823280999265 1.81581723414896 0.0704993729734349 7.36652177287903 8.59089022999786 0.857480607441177 0.39193421989761 LRRTM2 other 1 1 1 1.81581723414896 0.857480607441177 3.31105876617136e-22 489.975389587084 62.1859485980493 7.87919780325508 8.03264930780755e-14 -324.590800419109 104.905318916681 -3.09413101042959 0.00218037813178734 ZMAT2 essential 4.9659259375038e-18 1 1.15405072605271e-09 7.87919780325508 -3.09413101042959 0.190487108080933 72.2138752036508 142.198659579097 0.507837945993312 0.611978553414952 -306.895528475931 234.312748901554 -1.30976880222967 0.191379212346902 GFRA3 other 1 1 1 0.507837945993312 -1.30976880222967 0.0671346375296067 26.4095833372147 12.2902733082395 2.14881985736716 0.0325280936679965 4.14225964807688 20.2710179735388 0.204343938399347 0.838236991634802 KLHL3 other 1 1 1 2.14881985736716 0.204343938399347 0.021175740365936 26.5259754102292 9.54228622046802 2.77983439160853 0.0058224313215406 11.1291336022894 16.6233049482181 0.669489829907881 0.503757287455672 DCDC2 other 1 1 1 2.77983439160853 0.669489829907881 0.0142952456160644 40.2366237273453 50.4765605719845 0.797134814087897 0.426078384215346 -180.172809221678 82.2153070742854 -2.19147523293787 0.0292781984051472 TRIM7 other 1 1 1 0.797134814087897 -2.19147523293787 7.00639220089492e-15 174.787752017132 34.4134115497493 5.07905912683059 7.11379398742226e-07 -224.082515099482 56.0519410588907 -3.99776548084304 8.27270708643662e-05 TRIM41 other 9.2281191677987e-11 1 0.00796673788651419 5.07905912683059 -3.99776548084304 2.01766929517769e-15 274.250316934293 52.5351189333485 5.22032351886812 3.54265892865146e-07 -335.999569026922 87.3533191137375 -3.84644307092025 0.000149230767145731 HIGD2A other 2.69822914844113e-11 1 0.00405138475080581 5.22032351886812 -3.84644307092025 3.01269707153996e-05 85.7246064776065 61.2698299991606 1.399132435634 0.162912573668236 -341.956685118591 102.586846669699 -3.33333849532967 0.000977205458011442 FAM193B other 0.235833926760148 1 1 1.399132435634 -3.33333849532967 0.0103974264421903 -48.5564059215674 19.2686960689566 -2.5199632475285 0.0123075289148029 39.8698620296233 48.7396221870058 0.818017461781902 0.414060611521542 PLA2G7 other 1 1 1 -2.5199632475285 0.818017461781902 0.0864667147739931 -421.008915839888 318.689674789051 -1.32106230337888 0.187590859142935 -1675.60273860967 790.006760888499 -2.12099797313781 0.0348266768842498 TNFRSF21 other 1 1 1 -1.32106230337888 -2.12099797313781 2.32998371542433e-07 351.283300556582 101.79709501493 3.45081851800448 0.000647398874706787 -408.246744159933 169.450959371444 -2.40923241552759 0.0166483985770646 RNF44 other 0.0021783017755502 1 1 3.45081851800448 -2.40923241552759 4.96484399508679e-19 241.389432078873 27.4317623757754 8.79963265838293 1.7484144694391e-16 -123.544137899479 69.428236089495 -1.77945091014882 0.0763033160529401 MUT other 7.15880855651565e-15 1 2.60566208380509e-12 8.79963265838293 -1.77945091014882 0.478681583470864 -9.16068614604906 26.3145777962867 -0.34812210239382 0.728017754189036 -52.7280698210027 44.0596874122634 -1.19674180453506 0.232449244086095 DOK3 other 1 1 1 -0.34812210239382 -1.19674180453506 2.21068507861031e-09 305.623410507741 51.5141633816174 5.93280353295616 9.06349227962335e-09 -30.2721711871922 89.6009199242212 -0.337855584661346 0.735733583374822 ABT1 essential 2.34487366288196e-05 1 0.000112767970943074 5.93280353295616 -0.337855584661346 5.75518231243515e-05 276.245597772199 104.409793413442 2.64578243803549 0.00862647543794665 -523.209678824237 205.318740502192 -2.54828018886396 0.0113777274403892 PPP1R18 other 0.438314684915061 1 1 2.64578243803549 -2.54828018886396 0.318111728246295 -44.4118073280143 33.8675993979782 -1.31133614774791 0.190846049712674 -83.8271157187729 70.5288229154262 -1.18855118026418 0.235649204540068 DAAM2 other 1 1 1 -1.31133614774791 -1.18855118026418 9.45642728203361e-13 141.137166883748 19.0434121441934 7.41133814754844 1.85620839308974e-12 2.23924414397715 40.4973137567081 0.0552936463250291 0.955947991775783 PRIM2 other 1.16692312660295e-08 1 2.59924861284356e-08 7.41133814754844 0.0552936463250291 0.301244391430448 10.2657380123226 11.0738496745591 0.927025227361259 0.354756952437435 -23.3546225475888 26.6335547439064 -0.876887173798392 0.381342152375449 MLIP other 1 1 1 0.927025227361259 -0.876887173798392 0.455656266640455 7.5947001243372 6.82483647530332 1.11280323738448 0.266809027432465 -3.48745865199644 16.5358578959377 -0.21090279524313 0.833126440843345 HMGCLL1 other 1 1 1 1.11280323738448 -0.21090279524313 0.702026711472313 3.49122511052341 11.8452490996613 0.29473631843025 0.768454417509367 -16.4928208156157 23.8173906260758 -0.69246967791505 0.489323215866882 LGSN other 1 1 1 0.29473631843025 -0.69246967791505 0.00565186176235655 -64.9795716362823 22.291454966607 -2.91499912112613 0.00385514766557901 8.66732915781262 43.6374161405095 0.198621502471741 0.842708308375631 FGD2 other 1 1 1 -2.91499912112613 0.198621502471741 0.336254556766741 -26.116104794285 98.324178774478 -0.265612234140154 0.790739065764051 234.160993146277 189.080314932673 1.23842079081398 0.216627821185179 SCUBE3 other 1 1 1 -0.265612234140154 1.23842079081398 0.0675799044535711 9.11424966454527 6.96892217952781 1.30784207797867 0.192043438870248 -10.74321159775 10.9910121650979 -0.977454254110027 0.329222527180805 ANO7 other 1 1 1 1.30784207797867 -0.977454254110027 0.428294577256779 -1.89158916761335 4.51022428976917 -0.419400243997657 0.675254686860884 -14.3329906608778 10.9897543063407 -1.3042139306616 0.193263204625108 CRIP3 other 1 1 1 -0.419400243997657 -1.3042139306616 0.377060278183372 6.19423319268459 5.56990172654663 1.11209021214187 0.267081313203155 -5.85728437168888 13.571797665154 -0.431577637406697 0.666390291705757 TTBK1 other 1 1 1 1.11209021214187 -0.431577637406697 0.779422939711821 1.96260508261666 3.97503015632564 0.493733381995476 0.62189736817343 -2.84394627500241 9.21214126333174 -0.30871718026324 0.757775625729685 TCTE1 other 1 1 1 0.493733381995476 -0.30871718026324 8.15378044592127e-37 1206.51414451924 86.6174569621539 13.9292261263963 1.33117818877809e-33 -214.319955010297 210.567749722848 -1.01781946804478 0.309674915529546 RPL7L1 essential 1.29090652019826e-32 1 2.10778754411122e-29 13.9292261263963 -1.01781946804478 0.0777826926190955 52.8039832908417 30.2669943819451 1.74460610870369 0.0821955455672931 -54.6557601254675 70.1438270648695 -0.779195581600095 0.43654945847469 NFKBIE other 1 1 1 1.74460610870369 -0.779195581600095 0.235418181307297 13.7446802696658 11.5701601549255 1.18794209290306 0.235892490940152 -22.8461679594328 29.3968253341068 -0.777164462481132 0.437737116123625 CYP39A1 other 1 1 1 1.18794209290306 -0.777164462481132 0.00129924907348949 206.244745703335 103.032442413073 2.0017456722657 0.0463050815498561 -580.473530224245 248.646367312908 -2.33453452989221 0.0202957526336308 TPBG other 1 1 1 2.0017456722657 -2.33453452989221 6.26269763527447e-09 63.0816818673676 10.7252433686602 5.88160843526368 1.20679640531487e-08 -10.3031225846343 24.9258966039061 -0.41335012931971 0.679680653372113 IRAK1BP1 other 6.46310395960325e-05 1 0.000149341055157715 5.88160843526368 -0.41335012931971 1.44498719116797e-14 426.80896583707 58.1843413217798 7.33546098728981 2.63070830372805e-12 -224.648999072499 135.222747484772 -1.66132550366792 0.0978174066491175 PHIP other 1.88599728191243e-10 1 3.67220572117399e-08 7.33546098728981 -1.66132550366792 0.109747469829739 2.47305451160224 3.11842518432722 0.793045965646853 0.428439717867585 -11.9772284093216 7.45415282173407 -1.60678600181092 0.109257286609506 PRSS35 other 1 1 1 0.793045965646853 -1.60678600181092 8.65531590144804e-14 200.853908134428 28.2127547677806 7.11925899429736 9.9632470373038e-12 -51.3631000604105 51.5355592343434 -0.996653588774524 0.319831696009583 MMS22L other 1.10571660640999e-09 1 1.37114205727375e-07 7.11925899429736 -0.996653588774524 1.48587936640501e-06 182.138443173765 39.1457333474694 4.6528300174389 5.15102544784282e-06 -40.0824775780571 71.3815641493484 -0.561524226258119 0.574909472194501 FAXC other 0.0130489925957688 1 0.054137277456828 4.6528300174389 -0.561524226258119 0.00460467750298691 35.535568904873 12.5521109834777 2.83104323660365 0.00498596893263528 -20.6639173220567 28.0089159574344 -0.737762123798723 0.461295002877303 GABRR1 other 1 1 1 2.83104323660365 -0.737762123798723 2.79564427742833e-05 453.511651272448 115.940256770386 3.91159778238723 0.000115883144365293 -306.575057942392 260.001318394414 -1.17912885917497 0.239377240237461 PNRC1 other 0.219765596648641 1 1 3.91159778238723 -1.17912885917497 1.28932152504692e-20 375.203622100147 38.0498167248828 9.86085228249685 8.27225810559786e-20 -10.4431589139632 84.9047718145452 -0.122998492202227 0.902199125076824 PM20D2 other 1.89904167424161e-16 1 1.26557276757542e-15 9.86085228249685 -0.122998492202227 2.69646619101401e-35 375.993319343614 27.3785711975867 13.733124224421 6.18344583289497e-33 -64.0426570666384 68.8783072111348 -0.929794294600279 0.353305077787981 RARS2 essential 4.26149516827854e-31 1 9.78406634138971e-29 13.733124224421 -0.929794294600279 0.0360954255169801 -7.12504208099427 3.76829022343016 -1.89078910023776 0.0597310897543216 5.91320206317846 6.57449877302587 0.899414885806869 0.369239125565682 SCML4 other 1 1 1 -1.89078910023776 0.899414885806869 1.01294929786132e-07 52.1984218024296 12.4982640409499 4.17645375641004 4.00431713479037e-05 -52.4923537344626 22.9290329841812 -2.28934005942062 0.0228345138897127 TBC1D32 other 0.000970304132421356 1 0.390460963813409 4.17645375641004 -2.28934005942062 5.50646991810662e-05 319.514952346043 95.6430031153324 3.34070388777684 0.000954467314462059 -300.326639047142 177.553653543751 -1.69146977858801 0.0919095392074244 RNF217 other 0.420033525353173 1 1 3.34070388777684 -1.69146977858801 0.298407258009448 -6.00842529522987 18.7657005584482 -0.320181241116784 0.749076760768709 46.5260105650736 34.94011658737 1.33159288260336 0.184108838622477 RSPO3 other 1 1 1 -0.320181241116784 1.33159288260336 0.579894404158508 -7.68774008893417 72.6363764671231 -0.105838705932885 0.915788337920389 -137.476346389559 135.349367987381 -1.01571472725589 0.310667879392032 ARHGAP18 other 1 1 1 -0.105838705932885 -1.01571472725589 0.000127202528389331 462.551723221572 120.46874680651 3.83959936069142 0.000153469709403666 -152.901236864459 220.1942095434 -0.694392632674213 0.488030866492606 ABRACL other 0.930486495167955 1 1 3.83959936069142 -0.694392632674213 0.00593349792160965 42.6000350515971 36.8485132667754 1.15608558595518 0.248660577393516 -172.265444661979 68.9073322909799 -2.49995811671451 0.0130100415299639 SLC18B1 other 1 1 1 1.15608558595518 -2.49995811671451 1.27078498054745e-07 53.4906311702601 9.92747252544205 5.38814194984421 1.54723354572426e-07 -7.68397373379281 18.1455524644456 -0.423463201181051 0.672293223165421 MTFR2 other 0.00120851651650063 1 0.00180933490836994 5.38814194984421 -0.423463201181051 0.721214218945224 -34.3491056333163 132.191957333936 -0.259842628296558 0.795182465722879 156.366396460143 241.543392499865 0.647363584827644 0.517944652200687 SLC2A12 other 1 1 1 -0.259842628296558 0.647363584827644 1.64545332248387e-08 101.964934209031 20.4767629151726 4.97954362373742 1.13821330551892e-06 -63.2913333560592 36.1665151184371 -1.74999811700946 0.0812546087703416 SHPRH other 0.000165400967976079 1 0.0125647366796234 4.97954362373742 -1.74999811700946 0.000558768724034128 114.768670554672 55.4856910725178 2.06843725537587 0.0395439296020857 -240.686755200059 98.6892182477614 -2.43883536087812 0.0153745521851664 AIG1 other 1 1 1 2.06843725537587 -2.43883536087812 5.70756981828916e-13 808.378295473048 106.034526865922 7.62372709499822 4.09387795081502e-13 78.9235897446469 209.990934679669 0.375842842287649 0.70732561917405 DYNLT1 other 7.09964609696988e-09 1 5.82067567046879e-09 7.62372709499822 0.375842842287649 4.16474543570726e-15 106.141746768923 16.4395847721697 6.45647370294951 4.88129214776178e-10 -109.07565357553 32.0613863932707 -3.40208786474759 0.00076887556954947 TIAM2 other 5.52578424409639e-11 1 6.37496754497689e-06 6.45647370294951 -3.40208786474759 9.490957768589e-14 251.528509074723 53.659255984191 4.68751391463251 4.37097464781026e-06 -521.320993963923 106.266870342939 -4.90577159449168 1.60126933307818e-06 TMEM181 other 1.21066657296121e-09 0.0249814028653528 0.0462055730020023 4.68751391463251 -4.90577159449168 0.255157753225554 51.6188149507504 36.1433762576397 1.42816804337253 0.154386496683584 -26.0812024273769 71.5454798971982 -0.364540184297488 0.7157368818418 PNLDC1 other 1 1 1 1.42816804337253 -0.364540184297488 5.1086049947296e-21 931.085901473603 94.5107772158141 9.85163733599906 8.85074139666121e-20 -113.5401447912 187.182630567625 -0.606574148717183 0.544639489097179 WTAP essential 7.56533313669507e-17 1 1.3538094040333e-15 9.85163733599906 -0.606574148717183 1.9874860391107e-09 274.433407902356 81.1666733570805 3.38110946958523 0.00082786515901145 -353.804608777196 116.082041235963 -3.04788410860218 0.00253140157841024 ZMYM4 other 2.11349265399031e-05 1 1 3.38110946958523 -3.04788410860218 1.41668892979037e-12 117.95442789397 22.8785237895463 5.15568351258162 4.86930193934815e-07 -163.298925978235 43.4164691422168 -3.76122078106643 0.00020705519320612 ARMT1 other 1.73643562124406e-08 1 0.00550669356320882 5.15568351258162 -3.76122078106643 0.0511612493977629 82.7181949307782 42.7002250036868 1.9371840528624 0.0537581400826291 -67.1213970968056 80.2224509946268 -0.836690929591534 0.40350079077209 SLC22A3 other 1 1 1 1.9371840528624 -0.836690929591534 0.0392092408858671 47.8424533517069 25.4597517729824 1.87914060507364 0.0612944623963417 -84.718616053903 66.0760375352136 -1.28213826394711 0.200885841024618 VWDE other 1 1 1 1.87914060507364 -1.28213826394711 3.16515592530462e-07 312.939222315801 63.9927964716372 4.89022576868479 1.72521579198468e-06 -280.173457264803 174.569830763188 -1.6049362942035 0.109668217219298 GNA12 other 0.00293504908953497 1 0.018806577348425 4.89022576868479 -1.6049362942035 3.29787122464551e-10 381.195581640456 57.8160603060582 6.59324726767163 2.26645874015181e-10 -58.8926047242152 138.835238798113 -0.424190610640672 0.671765839168598 C7orf50 other 3.65766897525434e-06 1 2.99399199574055e-06 6.59324726767163 -0.424190610640672 4.96955542685591e-08 673.219116183737 137.052110144675 4.9121397362877 1.56314309402832e-06 -844.98272142115 378.266251180663 -2.23383058568865 0.0263132774635161 SDK1 other 0.0004849292185526 1 0.0171117274503281 4.9121397362877 -2.23383058568865 0.252800426147289 -4.41962489165427 21.9012367013951 -0.201797960175132 0.840226632073312 -109.262422997152 66.5113143493515 -1.64276445392809 0.10159572640008 WASH2P other 1 1 1 -0.201797960175132 -1.64276445392809 1.17608041509101e-15 262.126114831172 36.110610747616 7.25897760808374 4.06494240662681e-12 -325.209310443082 95.5737842265286 -3.40270413142031 0.000767214574803501 CCZ1B other 1.58124011808986e-11 1 5.64823747400795e-08 7.25897760808374 -3.40270413142031 4.70480752833116e-11 121.359670115355 21.0245776542 5.77227624313827 2.12093446195421e-08 -165.889153080963 55.7109803050329 -2.97767427843981 0.00316524884862558 C7orf26 essential 5.43593461823383e-07 1 0.000259029725838467 5.77227624313827 -2.97767427843981 7.46757101589803e-13 157.088084603903 21.0002584894033 7.48029290606919 1.0181872723959e-12 -50.792026402214 58.9461227935316 -0.861668655971172 0.389626087547631 RBAK other 9.24783994608812e-09 1 1.43442222935135e-08 7.48029290606919 -0.861668655971172 0.00164152715578752 97.8100268096513 29.8557967754196 3.27608161140013 0.00118916539148583 -34.461021588825 82.1015415000254 -0.419736596405005 0.67500922658711 CREB5 other 1 1 1 3.27608161140013 -0.419736596405005 5.62826841429797e-24 3893.7425521752 338.875303111014 11.4901927535853 1.33969640961251e-24 621.930349065849 1053.97528992443 0.590080578749089 0.555696448778112 EGFR og 8.56341039235436e-20 1 2.09006036863647e-20 11.4901927535853 0.590080578749089 2.43442788809027e-10 416.528783525709 64.3518763933114 6.47267503094908 4.49419599314662e-10 -63.7977816607584 148.848182724857 -0.428609745129959 0.668547732166998 CDCA5 essential 2.71852562263041e-06 1 5.87840835903578e-06 6.47267503094908 -0.428609745129959 2.15095399521615e-05 8354.29656936575 1783.57350646698 4.68402145416169 4.44758879348184e-06 3734.79131217486 4903.68742272933 0.761629155819261 0.446941221789204 IGFBP3 other 0.171108390319445 1 0.0469754328367552 4.68402145416169 0.761629155819261 0.266668874173579 3.24635366812931 2.3600810396729 1.37552635420487 0.17010002970675 -2.79710141493788 6.48878877140246 -0.431066800519895 0.666761220591005 IGFBP1 other 1 1 1 1.37552635420487 -0.431066800519895 0.0647035255330995 11.1761874049219 12.2058037213725 0.915645348724744 0.360669990260909 95.7565514241164 40.8558748110128 2.34376455937017 0.0198157507701623 SSC4D other 1 1 1 0.915645348724744 2.34376455937017 1.05721726960792e-26 1793.07510056292 158.120143790379 11.3399536427188 1.23195589894474e-24 -568.460119475088 517.009710290546 -1.09951536336838 0.272522734633627 MDH2 other 1.6335064032712e-22 1 1.92259037589316e-20 11.3399536427188 -1.09951536336838 8.50795423607503e-11 91.6996772236902 15.2652400155707 6.00709043095001 6.08547719848894e-09 -89.5853794401085 51.2316223104846 -1.74863444489781 0.0814906806262796 POMZP3 other 9.70842657878522e-07 1 7.62571147742649e-05 6.00709043095001 -1.74863444489781 6.4009665930071e-12 663.052815714723 92.7776096803108 7.14669000418789 1.07130373462085e-11 -292.528269486923 289.509624030579 -1.01042675339879 0.313312727937594 NIPSNAP2 other 7.64275411205048e-08 1 1.47250698323636e-07 7.14669000418789 -1.01042675339879 9.44586694545327e-28 2622.43834579298 212.132656021189 12.3622566887157 1.81112125414428e-27 -406.29848756756 661.953306416517 -0.613787231862405 0.539939687165004 CCT6A essential 1.46665976062053e-23 1 2.84472815388441e-23 12.3622566887157 -0.613787231862405 1.88427260348826e-13 444.72932264816 55.5386969540858 8.00755773971112 5.11157869757698e-14 30.0238273480222 173.306763665608 0.173240944051973 0.862608672145067 PSPH other 2.38172057080916e-09 1 7.36476258746891e-10 8.00755773971112 0.173240944051973 1.00885364565733e-05 44.7525509894196 10.2508998416669 4.36571927154274 1.84557042199262e-05 -25.1898179079456 30.8580336944707 -0.816313124723149 0.415085975107639 ZNF92 other 0.082625113579335 1 0.185479827410258 4.36571927154274 -0.816313124723149 2.73351482537935e-07 33.2602545471309 7.37848846722607 4.50773280935072 9.80056082115281e-06 -59.0464896659977 27.6418944686107 -2.13612311316249 0.0335755182683836 ATXN7L1 other 0.00254380889649802 1 0.10071663378584 4.50773280935072 -2.13612311316249 1.53413033333446e-10 142.166557552447 26.6902063886053 5.32654395708012 2.12761980112657e-07 -201.939707573891 77.0609333906126 -2.62051987548973 0.0092825407964973 TMEM168 other 1.72911829870127e-06 1 0.00246697515940626 5.32654395708012 -2.62051987548973 2.54280256372684e-17 274.093195460255 33.1404886706608 8.27064435241442 5.9098778980862e-15 -317.104812638273 141.637319517159 -2.23885070487978 0.025971469767416 SLC12A9 other 3.55839790767934e-13 1 8.63965049921222e-11 8.27064435241442 -2.23885070487978 5.70909674164607e-11 422.955404040121 62.5634440921182 6.76042392131358 8.37012060603276e-11 -211.142906342623 274.75438996345 -0.768478736120325 0.442869516147559 GIGYF1 other 6.56774489158964e-07 1 1.12126135638415e-06 6.76042392131358 -0.768478736120325 3.51684425564313e-18 147.618764463933 16.6233015511053 8.88023140349743 9.40121049440298e-17 -146.133814800146 75.2347760701232 -1.94237056894993 0.0531281319250578 TRIM4 other 4.99778737169445e-14 1 1.40435282365392e-12 8.88023140349743 -1.94237056894993 4.41694781415168e-24 329.226011555286 31.7571180334714 10.366999020764 1.93545363157947e-21 -349.244092853894 140.103012225471 -2.49276648165028 0.01327035697071 MEPCE essential 6.72789491051584e-20 1 2.98253404626396e-17 10.366999020764 -2.49276648165028 8.7481981980181e-17 179.481840861536 24.4482296074838 7.34130216147003 2.45591910787114e-12 -160.531154139286 65.6278949358046 -2.44608111072759 0.0150756665413652 TMEM209 other 1.20926343691204e-12 1 3.42993662605283e-08 7.34130216147003 -2.44608111072759 0.000272769311821245 1.82440499878191 1.73926729952064 1.04895032482053 0.295132108624297 -15.1264254835591 4.63446382074796 -3.26389978832931 0.00123945308576297 AGBL3 other 1 1 1 1.04895032482053 -3.26389978832931 4.36340805967852e-13 62.9792572543367 8.73532667544744 7.20971974996124 5.51184621000109e-12 -10.2856506787118 24.1121694742535 -0.426575082333202 0.670025030461689 ZC3HAV1L other 5.44509691767282e-09 1 7.6283951546415e-08 7.20971974996124 -0.426575082333202 8.89955304362182e-12 84.8550486396184 23.2741221953627 3.64589684316968 0.000319199309432237 -286.393578874261 62.0163889149205 -4.61803055426463 5.98192227098624e-06 TMEM140 other 1.05762288370402e-07 0.0924087352421954 1 3.64589684316968 -4.61803055426463 5.0966911966883e-14 129.05672891235 17.0297551364191 7.57830796030384 5.61842847293383e-13 -44.1800083412978 36.7842788432107 -1.20105680281543 0.230781723091416 TLK2 other 6.55740289365917e-10 1 7.95906577475806e-09 7.57830796030384 -1.20105680281543 1.53739349400963e-09 267.402876280536 50.3303150317533 5.3129585243373 2.25856461923453e-07 -214.320599403684 136.608765012317 -1.56886418952957 0.117850758290824 EPHA1 other 1.64467035038039e-05 1 0.00261406269030204 5.3129585243373 -1.56886418952957 1.49611388559003e-21 204.425865161235 23.4991651342243 8.69928203804604 3.48932314621934e-16 -99.7015997207414 59.9253314531128 -1.66376384248706 0.0973328286901946 NOM1 essential 2.22756396425499e-17 1 5.18164487213572e-12 8.69928203804604 -1.66376384248706 7.7525177939391e-18 343.860716062962 43.3074905639485 7.93998247382199 5.89191779653444e-14 -128.494213651518 111.146597303562 -1.15607869938273 0.248698067695345 NCAPG2 essential 1.09512066357184e-13 1 8.48023728455201e-10 7.93998247382199 -1.15607869938273 1.78838644479083e-19 545.664716944653 66.5702642587776 8.19682365723379 9.68391890524502e-15 -436.560902449454 183.754260532136 -2.37578655964336 0.0182020384556505 LUC7L2 other 2.59441221545805e-15 1 1.41133434125041e-10 8.19682365723379 -2.37578655964336 0.138791212825786 5.54927676327406 17.0023794982463 0.326382361001085 0.74438514858775 -79.9411861199475 46.9317601000066 -1.70334941518497 0.0896407284977411 DENND2A other 1 1 1 0.326382361001085 -1.70334941518497 1.56777514467016e-30 135.842913988886 18.9242266620636 7.17825443621446 6.74015534615678e-12 -144.26172776753 31.7093007664718 -4.54950832344012 8.10939655648813e-06 MCPH1 other 2.45905531441515e-26 0.125030676107934 9.30815453304251e-08 7.17825443621446 -4.54950832344012 4.99572221951392e-09 625.428619156237 131.502451041218 4.75602252432699 3.22329861737895e-06 -144.13792308933 232.893213201554 -0.618901345848099 0.53650510444639 MFHAS1 other 5.18306180274569e-05 1 0.0344248292336072 4.75602252432699 -0.618901345848099 1.54900458637769e-20 165.282963647565 40.9288108778863 4.03830358376884 7.14983080264209e-05 -350.992744916822 67.9571369500073 -5.16491365984164 4.88960089174334e-07 FBXO25 other 2.27920534839613e-16 0.00768400780137467 0.681378875491791 4.03830358376884 -5.16491365984164 0.00579417002305178 -20.5510878040747 38.034666349216 -0.540325176389995 0.589414937724386 -182.031740157048 63.2196368172564 -2.87935441140277 0.0043016566807507 CSGALNACT1 other 1 1 1 -0.540325176389995 -2.87935441140277 3.85871872464111e-12 141.083695568612 132.800430249565 1.06237378375568 0.289008343659855 -1190.19890395915 220.735338979145 -5.39197261962478 1.51367892934886e-07 ATP6V1B2 essential 4.64937019132008e-08 0.00238903945419131 1 1.06237378375568 -5.39197261962478 3.43004942616794e-32 215.893129395774 30.8624649823761 6.9953300722758 2.05572200605898e-11 -264.318879682681 52.3933366608566 -5.04489495283768 8.3069648125547e-07 CCDC25 other 5.39752577701786e-28 0.013019505950717 2.80338809966263e-07 6.9953300722758 -5.04489495283768 2.41045451940707e-19 69.7859411602424 12.5423144011287 5.56404017060537 6.34549455014527e-08 -67.3720082513214 21.3387021333538 -3.15726832073889 0.00177316827075159 HMBOX1 other 3.4913023259092e-15 1 0.000757652049287345 5.56404017060537 -3.15726832073889 0.717363998580488 1.44283796743079 8.05031433092909 0.179227531760771 0.85796878168146 -12.3793099530202 20.3335227413674 -0.608812851097129 0.543447086725752 CHRNA6 other 1 1 1 0.179227531760771 -0.608812851097129 4.71088741475549e-05 1.82014460309286 2.38800338141455 0.762203528378041 0.446598967900567 -12.3381008378736 4.04071871462091 -3.05344214959322 0.00248651933010215 GNRH1 other 0.361560609082484 1 1 0.762203528378041 -3.05344214959322 2.69738052325128e-24 89.6866820613861 23.9817068782634 3.73979560823823 0.000224416429071213 -251.754304345468 39.9862222776086 -6.29602623117626 1.21416229251981e-09 BIN3 other 4.11377503601052e-20 1.93343203460855e-05 1 3.73979560823823 -6.29602623117626 0.124795810540823 -59.3695733347977 42.8196703693315 -1.38650234396292 0.166728933598104 -145.036384602713 71.1730710223406 -2.03779860162542 0.0425376124550967 DOK2 other 1 1 1 -1.38650234396292 -2.03779860162542 5.86856594300291e-07 8.27322990853505 101.204949138503 0.0817472858685283 0.934907576124514 -722.384487636022 168.74543636067 -4.28091273586815 2.57942824076001e-05 SLC25A37 other 0.00532513673668084 0.392692155373304 1 0.0817472858685283 -4.28091273586815 1.55279948247154e-32 162.128542329453 35.7907398063678 4.52990195806479 8.82883049496361e-06 -452.106747202741 59.6761725361022 -7.57600107361493 5.55028692562209e-13 CHMP7 essential 2.44488278515143e-28 8.85992301937054e-09 0.0910517288945597 4.52990195806479 -7.57600107361493 9.19418498683849e-06 -34.3678235607445 51.9930485821298 -0.661008048151976 0.509166632161919 -374.241972539573 88.3067065717255 -4.23797905129212 3.09169841782637e-05 DOCK5 other 0.0756129773317597 0.469659906652004 1 -0.661008048151976 -4.23797905129212 0.333320577698098 25.1551442469009 32.2372852178451 0.780312116138619 0.436116085824166 -47.2660143449695 68.2339789442912 -0.692704940797301 0.489286413994442 STAR other 1 1 1 0.780312116138619 -0.692704940797301 1.36592566053509e-19 321.755406325613 46.3733351598079 6.9383710534687 4.59620322353972e-11 -257.218454812307 95.7023626763248 -2.68769179379872 0.00775789634044167 PLPBP other 1.9852363550217e-15 1 6.20487435177862e-07 6.9383710534687 -2.68769179379872 2.06345188090972e-21 522.395909645908 78.8799478792857 6.62267057332947 2.73385661717706e-10 -595.663022163024 162.789563869312 -3.65909833532832 0.000317803408510379 ERLIN2 other 3.06897198247703e-17 1 3.6007625504839e-06 6.62267057332947 -3.65909833532832 0.925563931053184 1.47998517090004 5.12285389044067 0.288898571489949 0.772908377249587 5.96820892871041 17.177613918793 0.347441091465035 0.728564463688026 PXDNL other 1 1 1 0.288898571489949 0.347441091465035 0.766734837531272 3.15105207969241 16.8395261499274 0.187122372187771 0.851718923744702 -32.9769125014564 55.145749253665 -0.597995547213727 0.550393029138191 ST18 other 1 1 1 0.187122372187771 -0.597995547213727 0.190044577723644 13.6529625808928 7.81241986750534 1.74759713538699 0.0817665104762903 2.89610567512745 25.4308311360817 0.113881676128878 0.909423359848989 RGS20 other 1 1 1 1.74759713538699 0.113881676128878 0.00588785599257225 378.960694061238 170.182033311966 2.22679613520983 0.0271229726845487 -450.137407712318 413.388816160749 -1.08889595004737 0.27756463813797 TACC1 other 1 1 1 2.22679613520983 -1.08889595004737 4.35301346185102e-19 423.566671375292 52.5103649215074 8.06634408289564 9.8709703268125e-14 -306.761177327421 132.969370053179 -2.30700632186748 0.0221929212761748 GOLGA7 other 6.28052782275865e-15 1 1.41648424189759e-09 8.06634408289564 -2.30700632186748 1.76297596637345e-14 226.917329928072 42.2934412573496 5.36530779198864 2.22391282650825e-07 -279.514370268913 90.004977459027 -3.1055434728169 0.00217500453556186 PLPP5 other 2.29592360100814e-10 1 0.00257468542261536 5.36530779198864 -3.1055434728169 3.57735210304751e-12 139.687845694085 21.8952090083285 6.37983613862514 1.45451175213558e-09 -69.0409815464714 55.4441423778352 -1.24523490824293 0.214664034640164 GINS4 essential 4.31643304753713e-08 1 1.86861124796859e-05 6.37983613862514 -1.24523490824293 6.55286101665032e-19 697.601120135335 103.456982675431 6.74290997180801 1.75368959874356e-10 -750.435579899975 223.124526963894 -3.3633038470101 0.000928780104191758 NSD3 other 9.43480929177313e-15 1 2.3271460975327e-06 6.74290997180801 -3.3633038470101 0.852829622562538 -0.125285752857544 3.40041371459683 -0.0368442676018315 0.970636606289809 5.54581345813458 10.836395883312 0.511776564630228 0.60922882575057 DNAJC5B other 1 1 1 -0.0368442676018315 0.511776564630228 0.000103244879600609 13.5588532691514 7.9558381606518 1.7042645910284 0.0894820879974801 -79.9126101028203 25.5551793197977 -3.12706121537217 0.00195865686754938 ADHFE1 other 0.764115353924106 1 1 1.7042645910284 -3.12706121537217 3.94556310129064e-11 177.241410067478 25.183511380565 7.03799432053234 1.64430435872774e-11 78.23830760878 78.7326038185843 0.993721835861758 0.321258018873221 MRPS28 other 4.57014574022495e-07 1 2.24891507143193e-07 7.03799432053234 0.993721835861758 0.506617355430405 4.19180552678052 5.02986093106901 0.83338398103377 0.405367564880174 -7.71313226980794 16.314461349102 -0.47277884968188 0.636754332773944 PMP2 other 1 1 1 0.83338398103377 -0.47277884968188 1.06671166817349e-10 117.138657226524 17.6485004204755 6.63731503729474 1.72463608184423e-10 -10.1086946219187 56.625819143412 -0.178517410870775 0.858449538466961 LACTB2 other 1.211251099211e-06 1 2.28928193504004e-06 6.63731503729474 -0.178517410870775 7.65381942737762e-14 102.973078058719 14.6934600306468 7.00808916646888 1.96999654536954e-11 -89.7781135018 48.7352631755415 -1.84215920161187 0.0665606896890653 TERF1 other 9.79229657538692e-10 1 2.68845428546581e-07 7.00808916646888 -1.84215920161187 2.37997799240831e-09 719.391236461713 120.133214145375 5.98827927463231 6.82121287125267e-09 -229.487279958001 398.457803355172 -0.575938726825344 0.565141722221519 RPL7 essential 2.51992069836191e-05 1 8.52651608906584e-05 5.98827927463231 -0.575938726825344 0.490787949667019 2.52941584369288 4.26662189656873 0.592838059010354 0.553787585755284 -12.3723961963363 14.8347748691279 -0.834013074379987 0.40501360263359 SLC26A7 other 1 1 1 0.592838059010354 -0.834013074379987 0.556768683840748 12.3337243216782 12.9551689065682 0.952031147615924 0.341939005204209 -8.60617195680831 43.7357038402764 -0.196776802500726 0.844151347364219 ATP6V0D2 other 1 1 1 0.952031147615924 -0.196776802500726 0.0486239478437631 48.4088553786964 19.838168141676 2.44018777504961 0.0153304241968354 66.7140308417885 78.4830877596981 0.850043401019792 0.396062549815937 SYBU other 1 1 1 2.44018777504961 0.850043401019792 1.10101737639763e-13 655.408327693329 86.3893149925672 7.58668277147144 5.27916459406975e-13 -267.331442848239 314.915100884244 -0.848900043527934 0.396686149100732 MTDH other 1.40170522189182e-09 1 7.48321581209386e-09 7.58668277147144 -0.848900043527934 0.0563013352860211 107.380013009821 50.1083401282762 2.14295689569702 0.0330104906167613 -129.661855354673 202.248597932183 -0.641101380579909 0.522000613787421 LRP12 other 1 1 1 2.14295689569702 -0.641101380579909 1.53638227487463e-15 134.736717449089 15.5763251933943 8.65009659057638 4.88831351275445e-16 -3.76083754796392 61.6225292777199 -0.0610302367014929 0.95138078631044 EBAG9 other 2.06013499237939e-11 1 7.24790244536102e-12 8.65009659057638 -0.0610302367014929 0.204803141864122 31.6563984725804 17.7269501020155 1.78577805490529 0.0752574293250837 27.1942849540759 73.4567692606673 0.370208017964617 0.711517742641105 RSPO2 other 1 1 1 1.78577805490529 0.370208017964617 4.70651194953408e-11 250.626482042406 35.8026944458737 7.00021285887578 2.0373116015684e-11 17.3512188085964 140.170286247052 0.12378671167165 0.90157659638777 POLR2K other 5.43743325529672e-07 1 2.7788930245393e-07 7.00021285887578 0.12378671167165 0.0219477895383243 920.527216122653 333.612214099216 2.75927312376186 0.0061877690735317 1090.37791784385 1393.88659125812 0.782257268763649 0.434746354889945 MAL2 other 1 1 1 2.75927312376186 0.782257268763649 2.27339107641194e-17 1083.6238928985 115.655597497148 9.36940291995139 2.9727453206087e-18 248.794585283061 456.53510243981 0.544962663228864 0.586227388278964 EIF3H essential 3.18593025448369e-13 1 4.49954731727332e-14 9.36940291995139 0.544962663228864 6.64820316754075e-16 144.81976619133 16.3117539662704 8.87824610957164 9.53206699151727e-17 26.3112599336961 64.3884812245933 0.408633026176217 0.683131704215455 UTP23 essential 8.99169478409886e-12 1 1.42370952585302e-12 8.87824610957164 0.408633026176217 2.23631529180949e-09 762.907823784619 116.45748133972 6.55095589401534 2.87926228129205e-10 503.356226850715 504.159747731747 0.998406217702529 0.318976350109727 NDUFB9 other 2.37183599849314e-05 1 3.78939708840847e-06 6.55095589401534 0.998406217702529 0.267906845478664 346.190249436301 213.03639554643 1.62502866492994 0.105327482124568 182.160142880739 922.427843334467 0.197479016052087 0.843601838295173 FAM83A other 1 1 1 1.62502866492994 0.197479016052087 0.19601885390606 62.7406223192699 35.4012298766945 1.77227239103842 0.0775070303407702 -20.6674935062598 152.438480671891 -0.13557924098407 0.892257628596651 GSDMC other 1 1 1 1.77227239103842 -0.13557924098407 1.59057115524498e-14 123.909090909091 15.9661394207276 7.76074213333184 1.97599031031097e-13 -73.8433014354067 59.6836506417313 -1.23724505189324 0.217121020755693 ZNF7 other 2.07394572932393e-10 1 2.82408535149644e-09 7.76074213333184 -1.23724505189324 6.34031386436623e-08 74.8351063829784 15.9933075979022 4.67915132156867 4.62221453703645e-06 -136.695588496853 59.8727344891825 -2.28310247833346 0.0232255302393941 ARHGAP39 other 0.000614630026011662 1 0.0487504967221234 4.67915132156867 -2.28310247833346 1.09398932269963e-12 278.379140202055 36.1563308072114 7.69931942725039 2.67080071685067e-13 98.9973535387978 138.63770385308 0.714072368392003 0.475806197784294 SLC39A4 other 1.34604446264962e-08 1 3.81016430265916e-09 7.69931942725039 0.714072368392003 0.0057874531497764 265.089242725008 84.138144516344 3.15064284158909 0.00181310644358282 494.474297469126 318.644389754144 1.55180606773164 0.121884322376198 NAPRT other 1 1 1 3.15064284158909 1.55180606773164 6.52364053081728e-19 514.575642953771 65.4475941947911 7.86240730900274 9.63938612463251e-14 -599.603780762146 224.301795956439 -2.67320097998054 0.00798120133847937 VLDLR other 9.39339000032381e-15 1 1.383733878191e-09 7.86240730900274 -2.67320097998054 3.45945737763293e-28 613.750838012782 56.5899094893487 10.8455879069448 5.82595096196033e-23 -459.870492621135 198.937696448344 -2.31163073078281 0.021556697547393 AK3 other 5.3804940594325e-24 1 9.04304108315482e-19 10.8455879069448 -2.31163073078281 3.93483224376798e-35 291.924462482627 25.4025563888688 11.4919324659209 4.70573153737183e-25 -386.840972944547 88.3234777183776 -4.37982043888719 1.71419245109669e-05 UHRF2 other 6.21624797870465e-31 0.26237429656486 7.35599953921965e-21 11.4919324659209 -4.37982043888719 6.42206855467074e-05 218.9908372896 126.589524533144 1.72992858688131 0.0848251909028418 -1415.74744497194 421.533608755181 -3.35856362474334 0.000900396584100627 NFIB other 0.486921237815135 1 1 1.72992858688131 -3.35856362474334 0.00381586570096441 37.5516734242541 99.9247363536308 0.375799574705504 0.707366556397424 -1095.69051971987 352.540431428041 -3.10798541682591 0.00208875846619842 PLIN2 other 1 1 1 0.375799574705504 -3.10798541682591 2.52077492557035e-33 279.128326575747 21.3449042792621 13.0770474734308 1.72809790053398e-30 -122.869480280133 75.306095747611 -1.63160072315967 0.103951395835615 HAUS6 other 3.97425374765421e-29 1 2.72797534578295e-26 13.0770474734308 -1.63160072315967 0.0316638113933814 283.99186112538 107.467508188622 2.64258347394573 0.00881348763460547 171.69852959467 321.563185438945 0.533949585554376 0.593910661590974 CDKN2B other 1 1 1 2.64258347394573 0.533949585554376 8.54792682268569e-11 830.00045375112 120.918244310432 6.86414575802367 6.66379190042017e-11 -75.7407438036329 361.801527893027 -0.209343349777193 0.834373055841254 CDKN2A ts 9.7523297120021e-07 1 8.960800968495e-07 6.86414575802367 -0.209343349777193 2.62348566044664e-10 181.776638769811 32.5892091361627 5.57781681691998 6.47432968334945e-08 -140.798778963256 88.8496309608946 -1.58468614264955 0.114338157375317 C9orf72 other 2.92466181426592e-06 1 0.000772711247707757 5.57781681691998 -1.58468614264955 2.11960745523288e-41 223.004853946279 16.9485786098027 13.1577319302338 1.01143202147436e-30 -98.6346371511918 41.9413540339261 -2.35172753534392 0.0194244295177219 ZCCHC7 other 3.36508879592772e-37 1 1.59715230511016e-26 13.1577319302338 -2.35172753534392 5.31289362621049e-29 247.841324490614 23.5327221881526 10.5317745439322 7.81152002658469e-22 -105.98669672121 57.4025184564274 -1.84637712022447 0.0659739646681891 FBXO10 other 8.29236437178934e-25 1 1.20609869210468e-17 10.5317745439322 -1.84637712022447 6.49188381224434e-32 779.601281614651 72.5322559419054 10.7483390870825 1.37109691383636e-22 -439.079799392445 192.215091054897 -2.28431491503985 0.0231470714697688 SIGMAR1 other 1.02058905412293e-27 1 2.12341779045837e-18 10.7483390870825 -2.28431491503985 7.1872338252921e-18 152.312586581702 25.3871865327923 5.9995851208231 6.31381079184558e-09 -177.127683366723 46.5527906754341 -3.80487787728251 0.000175405318460186 CEP78 other 1.0161311182198e-13 1 7.90615387354904e-05 5.9995851208231 -3.80487787728251 8.01894016759721e-10 3283.93484571845 1054.22936947866 3.11500982688655 0.00203529701346155 -7613.24816201084 2003.30540972046 -3.80034323526995 0.000178212988853684 NTRK2 other 8.71498417414465e-06 1 1 3.11500982688655 -3.80034323526995 4.02118057928531e-11 18.3527342448571 4.82449702896764 3.80407203790614 0.000175815457740242 -32.0805581504734 8.92198603716773 -3.59567455237324 0.000384120072062318 IDNK other 4.65612499275445e-07 1 1 3.80407203790614 -3.59567455237324 0.55486560400707 10.4305447830102 16.1593670828644 0.645479784543718 0.519162441622587 -14.8788088642659 30.303350049623 -0.490995511714094 0.623826988341454 SHC3 other 1 1 1 0.645479784543718 -0.490995511714094 2.08670919806954e-14 42.2670697759433 8.24223539011501 5.12810757948439 5.5662759182009e-07 -60.052922638313 16.1264164925206 -3.7238851338216 0.000238479615204322 AUH other 2.71293062841021e-10 1 0.00627430621499606 5.12810757948439 -3.7238851338216 1.89684857623209e-31 458.52999457243 60.2561304251104 7.60968205786657 4.64442182679232e-13 -807.445808925391 114.596573818072 -7.04598559994692 1.54451139067e-11 MFSD14B other 2.98032848297586e-27 2.46349566811865e-07 6.59322122531438e-09 7.60968205786657 -7.04598559994692 8.06411744795894e-05 60.1589099645859 23.8826953462322 2.51893302210869 0.01235352179066 -98.4319024428525 45.9311012480076 -2.14303379993795 0.0330109453936479 PLPPR1 other 0.604324961550043 1 1 2.51893302210869 -2.14303379993795 4.33197143454555e-06 160.719521927962 47.6940510738902 3.3698022774154 0.000861573662977771 -173.336048961989 92.6139513500129 -1.87159759879918 0.0623395068473309 ZNF462 other 0.036613822564779 1 1 3.3698022774154 -1.87159759879918 1.05060278526677e-27 147.733105305148 19.6048744986218 7.53552925398903 7.30481863953971e-13 -206.077857205009 37.0114184540086 -5.56795350767457 6.20023294840895e-08 INIP other 1.63106082412666e-23 0.000981062859426748 1.03187868102138e-08 7.53552925398903 -5.56795350767457 4.19982277091371e-08 213.504015762316 87.2366904812784 2.44741076930395 0.0150213806754371 -639.805137415693 169.024259005654 -3.78528585884404 0.000188918787814616 UGCG other 0.000411876619143507 1 1 2.44741076930395 -3.78528585884404 0.0041593001797097 187.317029285335 78.4601911043154 2.38741489982213 0.0176504903453878 -149.708153947303 148.317684120875 -1.00937494294541 0.313691918536104 SNX30 other 1 1 1 2.38741489982213 -1.00937494294541 0.000371219070430132 1202.99752366507 386.834747653597 3.10984866525572 0.00207069004390394 -740.47671875217 741.617661192384 -0.99846154898957 0.318943013325644 STOM other 1 1 1 3.10984866525572 -0.99846154898957 3.84666311743425e-08 2151.95319626785 736.270517322322 2.92277518335802 0.00376088185628759 -4980.76344527323 1411.53612071697 -3.52861210717251 0.000490285466780166 GSN other 0.000378050051181439 1 1 2.92277518335802 -3.52861210717251 3.06984214342957e-23 197.511175877585 28.5340557100519 6.92194540743137 3.19846203445165e-11 -276.608337919138 54.7038749449972 -5.05646699063381 7.85944094522803e-07 MRRF other 4.64467116300893e-19 0.0123220315139285 4.33647482630955e-07 6.92194540743137 -5.05646699063381 6.23462990838904e-05 24.3870406800298 7.17469290872486 3.39903616646417 0.000777537239334035 -16.8690886973668 13.8373688137436 -1.21909655834367 0.223863710488623 NR6A1 other 0.473333102644896 1 1 3.39903616646417 -1.21909655834367 0.0449498685619388 8.33399492446719 10.640264142043 0.783250755170354 0.434158823562982 -37.0608946769777 20.3386233912841 -1.82219287726522 0.0695197225080454 CRB2 other 1 1 1 0.783250755170354 -1.82219287726522 8.56508381856976e-13 177.157249091726 37.2560724973945 4.75512412383552 3.21999420791871e-06 -240.698393555204 69.9886397344497 -3.43910661027932 0.000675186903347708 ALAD other 1.05838740746066e-08 1 0.0343959781289877 4.75512412383552 -3.43910661027932 0.0267281457140892 141.097741477037 62.5635994700971 2.25526892109965 0.0249144542448253 -43.3966469577849 117.073200530678 -0.37067959841427 0.711165763605955 ASTN2 other 1 1 1 2.25526892109965 -0.37067959841427 1.08149751224795e-06 22.5460325028203 6.55540428805888 3.4393046579735 0.000674713863233731 -26.3938271061315 12.3920470852316 -2.12990048573869 0.0340775272247312 WDR31 other 0.00960477940627408 1 1 3.4393046579735 -2.12990048573869 1.69125973601427e-25 907.193747210764 107.462978112841 8.4419189114429 1.88521793214623e-15 -746.009545425967 201.878167927031 -3.6953453317231 0.000265479700465874 POLE3 other 2.59845145841232e-21 1 2.77428670894639e-11 8.4419189114429 -3.6953453317231 2.61104367281722e-12 1223.61781609022 211.948809093613 5.77317618024348 2.12531997350311e-08 -964.139890616626 402.22294858487 -2.39702854849215 0.0172061770622976 SURF4 other 3.16771818386185e-08 1 0.00025950156876473 5.77317618024348 -2.39702854849215 0.736794070358806 6.42237859584252 10.7136441673149 0.599457896449077 0.549368414019638 -4.72706398429036 20.2799068884981 -0.233091010243807 0.815866692279332 GBGT1 other 1 1 1 0.599457896449077 -0.233091010243807 2.31330609975407e-13 150.982000617419 31.7614440871084 4.75362518792716 3.24762011155609e-06 -248.559062852848 60.274845358474 -4.12376110423157 4.96107038185851e-05 SURF1 other 2.91476568569012e-09 0.74897279554918 0.0346690665782209 4.75362518792716 -4.12376110423157 1.07077465862896e-18 118.66609677281 16.1113412597547 7.36537665360186 2.13043647221411e-12 -95.2916263663105 30.5750771371091 -3.11664385796936 0.00202592228831271 SURF2 other 1.53452716328116e-14 1 2.97877627544977e-08 7.36537665360186 -3.11664385796936 2.95124326260371e-11 248.554784735141 45.6332888213362 5.44678657083615 1.14785794525131e-07 -204.895481546624 86.2910599219335 -2.37446940311071 0.0182683127154962 SURF6 essential 3.43495203334445e-07 1 0.00135343930324582 5.44678657083615 -2.37446940311071 2.94602561066709e-11 165.286134240814 28.5091026078074 5.79766176840476 1.8669187011801e-08 -96.9580433268347 54.1027588758765 -1.79210904104313 0.0742309505776256 MED22 essential 3.42917381081649e-07 1 0.000228622864146515 5.79766176840476 -1.79210904104313 2.4269284845427e-17 220.344244082115 27.6611481907757 7.96583867605303 4.56139333800355e-14 -77.5340607232979 52.4935649986255 -1.47702029239828 0.140831317242427 REXO4 other 3.39842795690514e-13 1 6.57935375073632e-10 7.96583867605303 -1.47702029239828 3.00090993606861e-18 3160.24539669748 476.786446300415 6.6282198691241 1.82882636029781e-10 -3542.17106360921 904.814946101218 -3.91480167173649 0.000114532285049479 RPL7A essential 4.27269556697448e-14 1 2.42502375375489e-06 6.6282198691241 -3.91480167173649 1.84700378305525e-09 570.997940146543 111.426022567002 5.12445770738335 5.6654797459788e-07 -383.331063035976 211.128655773285 -1.81562782954298 0.0705285282821322 GTF3C5 essential 1.96816723122368e-05 1 0.00638329602979431 5.12445770738335 -1.81562782954298 1.79441969929895e-14 185.53467690211 31.8863879592653 5.8186169326902 1.66447173695582e-08 -194.830024161379 60.9983037829011 -3.19402363801456 0.00156813636781395 ASB6 other 2.33597556454737e-10 1 0.000204496997602392 5.8186169326902 -3.19402363801456 2.65102150651458e-15 249.740727265943 47.5588118561646 5.25119778057642 3.05079237564737e-07 -367.012117989477 88.5371879865123 -4.14528771848263 4.53784530239267e-05 PTGES2 other 3.53248615743067e-11 0.686031452815724 0.00350322488495587 5.25119778057642 -4.14528771848263 2.71840848976471e-20 198.057855029985 26.8368881489893 7.38006038294881 1.9278165748981e-12 -183.49287907968 51.338667082363 -3.57416523466223 0.000415558178694077 NTMT1 other 3.98790525448483e-16 1 2.69836485988487e-08 7.38006038294881 -3.57416523466223 4.73285649580364e-17 588.788563006082 82.0485438958483 7.1761000872055 6.83000154818751e-12 -365.634094555767 152.744508775711 -2.39376261370326 0.017354330874329 CIZ1 other 6.58387667131245e-13 1 9.43086613773732e-08 7.1761000872055 -2.39376261370326 1.0574981950424e-12 285.683559088025 75.5165075786784 3.78306105841005 0.000190530323242775 -652.757233478863 140.584235951885 -4.64317516867447 5.34519046114932e-06 SLC25A25 other 1.3020975275557e-08 0.0826740608625965 1 3.78306105841005 -4.64317516867447 3.75335293127e-05 124.394463426277 90.81265385904 1.36979218358008 0.171885655027301 -580.703650108766 169.242261619222 -3.43119764858314 0.000694693229524687 SH3GLB2 other 0.291147586878614 1 1 1.36979218358008 -3.43119764858314 2.47156495688151e-06 81.9004620414722 26.036082547848 3.14565226511934 0.00184178267608871 -119.991609108009 48.521932867882 -2.47293547507121 0.0140145973959632 MIGA2 other 0.0212851174086635 1 1 3.14565226511934 -2.47293547507121 0.860273087717511 71.0795724227828 138.139246938492 0.51455016585136 0.607285230801666 9.74907643425573 264.25883545856 0.0368921493858038 0.970598060102391 PTGES other 1 1 1 0.51455016585136 0.0368921493858038 0.171205199111047 -244.323185566625 442.295553258394 -0.552398014781506 0.581129318740645 -1538.38685585283 823.393247561987 -1.86835009930904 0.0627882692658997 LCN2 other 1 1 1 -0.552398014781506 -1.86835009930904 7.89921792897728e-06 54.6752647298396 17.0328723447298 3.20998499978524 0.00148723947954955 -66.5849398135579 31.6000753021989 -2.10711332731933 0.0360266785089574 LRSAM1 other 0.0652870361829972 1 1 3.20998499978524 -2.10711332731933 0.379223420556959 -2.85092645455958 14.5658351550013 -0.195726947629274 0.844969494293849 32.8395045068425 27.8348184030765 1.17979948822705 0.239107025192501 HMCN2 other 1 1 1 -0.195726947629274 1.17979948822705 3.6802002584585e-19 710.272320548086 115.74310368892 6.13662756493096 2.95452191190092e-09 -1031.48117160603 221.181157023004 -4.66351286650856 4.87076155139843e-06 GPR107 other 5.31531323329161e-15 0.0754188718618532 3.75106101934941e-05 6.13662756493096 -4.66351286650856 6.44613530070195e-08 7.907943432759 4.43297043847037 1.78389266125756 0.0756209318644996 -26.9789711036494 7.56114437489017 -3.56810685869773 0.00042886785754394 IDI2 other 0.000624694971991026 1 1 1.78389266125756 -3.56810685869773 4.03276534049635e-09 107.374424251768 22.8374684306165 4.70167805936928 4.10624612474089e-06 -98.5399024841494 43.0143059952838 -2.29086347446716 0.0227363443428687 INPP5E other 4.20254476133125e-05 1 0.0435056776916297 4.70167805936928 -2.29086347446716 2.08823476610996e-12 724.600596345082 116.899566941317 6.19848828617839 2.1054279669475e-09 -415.862331129913 220.179997551254 -1.88873801323895 0.0599908034348278 SEC16A essential 2.54346994512193e-08 1 2.68715771421509e-05 6.19848828617839 -1.88873801323895 2.09643936262607e-09 166.95329107042 28.6918287490151 5.81884454040422 1.69859890465002e-08 -31.7473225127799 54.1233099999595 -0.586573927440943 0.557987352371981 DPH7 other 2.22641860310888e-05 1 0.000208621917469116 5.81884454040422 -0.586573927440943 0.000496176563463127 656.880308967105 210.489976580805 3.1207201389703 0.00199905934863347 -423.969654972957 395.914774048983 -1.07086090937466 0.285184758145461 NOTCH1 og 1 1 1 3.1207201389703 -1.07086090937466 4.27111875454489e-05 132.347452606636 45.2442948084005 2.92517439308309 0.00374187854088466 -182.145443585267 85.5120135055995 -2.13005677352387 0.0340917828768912 CACNA1B other 0.329345967162956 1 1 2.92517439308309 -2.13005677352387 0.0533261923246872 59.575006622721 34.3481331594135 1.73444671203022 0.0839675958057236 -59.8283987626497 64.1900645717699 -0.932050764581432 0.352133826808359 NACC2 other 1 1 1 1.73444671203022 -0.932050764581432 0.000242169879178465 92.1741940483567 34.3487021261972 2.68348404285287 0.00773090837382108 -60.2887105713054 58.1070168391414 -1.03754613213416 0.300399508438263 PROSER2 other 1 1 1 2.68348404285287 -1.03754613213416 1.39777268142296e-21 136.751487910724 31.7974120737544 4.30071125264937 2.37277627842391e-05 -299.20720565857 53.7910501544566 -5.56239755125474 6.34207005161493e-08 USP6NL other 2.0819824089795e-17 0.00100344232356651 0.236257334042668 4.30071125264937 -5.56239755125474 2.07511756440419e-06 223.573535866657 60.7297279008811 3.68145130226104 0.000280019414504074 -108.189908643465 101.605746459374 -1.06480108078064 0.287917259177573 COMMD3 other 0.0180057951063352 1 1 3.68145130226104 -1.06480108078064 4.0095572970802e-07 49.4853966492072 25.3539985163677 1.9517787940731 0.0519943931039046 -137.895527651555 42.4182051633345 -3.25085719965231 0.00129603156879557 MSRB2 other 0.00369159940342174 1 1 1.9517787940731 -3.25085719965231 1.790932085039e-12 64.5559294829161 10.3328815051579 6.24762119363235 1.60779476483298e-09 -9.17153511222245 17.1044406685648 -0.53620783572761 0.592254770446941 PDSS1 other 2.18690716904113e-08 1 2.06151444746884e-05 6.24762119363235 -0.53620783572761 0.000452345988652111 102.645037978501 88.6708413204409 1.1575963016699 0.248044313916793 -371.838494489824 149.401134200236 -2.48885991716411 0.0134136947387121 FAM171A1 other 1 1 1 1.1575963016699 -2.48885991716411 1.58078177609345e-06 46.2834824861582 21.7907641148701 2.12399538823763 0.034576218766646 -102.945540795139 36.751071159236 -2.80115755943805 0.00545878148346822 MINDY3 other 0.0138618753945635 1 1 2.12399538823763 -2.80115755943805 0.300297476810626 3.49475298615148 2.94516807276068 1.18660561971788 0.236418598108903 -0.816114641019651 5.00195624173286 -0.16315909247877 0.870514330756288 TMEM236 other 1 1 1 1.18660561971788 -0.16315909247877 6.46137582359622e-12 204.082791902412 66.0759893917077 3.08860743185517 0.00221989741108485 -435.763475480052 111.26761051846 -3.91635511403166 0.000113836612632277 RSU1 other 7.71359045820916e-08 1 1 3.08860743185517 -3.91635511403166 0.0795361598274346 7.62912224900083 8.76001601673147 0.870902773970887 0.384575232547353 -18.3781334758728 14.8776625679964 -1.23528366044585 0.21779085883119 ST8SIA6 other 1 1 1 0.870902773970887 -1.23528366044585 2.39915415365902e-07 490.901114469827 144.671912057019 3.39320264376095 0.000794788046367409 -524.359166791801 250.81101248178 -2.09065447965484 0.037497632645872 PARD3 other 0.00224104989493289 1 1 3.39320264376095 -2.09065447965484 0.223932079245378 -24.0032531530152 45.3223152216347 -0.529612245880088 0.59681121979584 -131.733738187721 78.0889589763353 -1.68697009045341 0.0927513542006193 ZEB1 other 1 1 1 -0.529612245880088 -1.68697009045341 0.0334042336420031 -9.44242908092466 15.4513011192501 -0.611108993867238 0.541643470103979 -55.8649980658175 23.2187337785343 -2.40603120732899 0.0168018180105351 FAM13C other 1 1 1 -0.611108993867238 -2.40603120732899 2.49844815664399e-09 121.033739686238 29.2094857116848 4.14364500905336 4.58275215916912e-05 -68.9196830378267 43.8747197141243 -1.570829021516 0.117397835578558 NRBF2 other 2.64085970157269e-05 1 0.444206166788263 4.14364500905336 -1.570829021516 0.00574996582677032 136.500156508682 68.1967919302647 2.00156272230902 0.0463322666937849 -74.6940120756234 99.2719770997227 -0.752417895340094 0.452455249308928 CDHR1 other 1 1 1 2.00156272230902 -0.752417895340094 2.50055515079466e-14 172.036470588235 35.9514325508301 4.78524660582024 2.81482370256491e-06 -143.832187028658 54.4700302534412 -2.64057475935716 0.00875853462985735 POLR3A essential 3.24572058573147e-10 1 0.0302143176233318 4.78524660582024 -2.64057475935716 8.99444494500189e-17 114.63126814683 36.59715248255 3.13224555384431 0.00192415536609183 -282.679523568793 57.1871531807194 -4.94305989800693 1.34670568672001e-06 HERC4 other 1.24267251360146e-12 0.0210301560038197 1 3.13224555384431 -4.94305989800693 1.19972391185975e-23 221.329578589653 42.859588433808 5.1640621545275 4.70729714587523e-07 -331.95422643168 67.1436622595458 -4.94393983379252 1.34908320590121e-06 CAMK2G other 1.82082098102954e-19 0.0210659342601474 0.00533195547713287 5.1640621545275 -4.94393983379252 0.051791047288367 -175.172976625739 277.310422528984 -0.631685513397645 0.52813285242856 -886.601761976694 394.989538961456 -2.24462086846105 0.0256115901220134 ADIRF other 1 1 1 -0.631685513397645 -2.24462086846105 2.12126884793245e-11 568.444922455846 185.076045138475 3.07141273756164 0.00235051722961728 -872.271801541562 264.216534078689 -3.30135206936665 0.00109333434492584 GLUD1 other 2.4840058209289e-07 1 1 3.07141273756164 -3.30135206936665 0.328753572120843 -53.1204871017715 111.382644942458 -0.476918887401303 0.63380281847646 -224.821533924196 159.420702025011 -1.41024052126508 0.15961118576092 ANKRD1 other 1 1 1 -0.476918887401303 -1.41024052126508 0.0134732794258963 36.3593606441462 25.4466673375249 1.4288456779772 0.154195957703996 -42.3826481637513 36.421523059009 -1.16367039607554 0.245577369459003 HTR7 other 1 1 1 1.4288456779772 -1.16367039607554 1.79363366563755e-15 160.802015255651 25.5448611871432 6.29488702551975 1.22765222914226e-09 -35.0074669340936 36.5620667895764 -0.957480525802059 0.339175026520316 RPP30 essential 2.40095802482242e-11 1 1.58219819291854e-05 6.29488702551975 -0.957480525802059 8.29661301251518e-15 107.394801563215 16.9016392905156 6.35410564130778 8.78837799021767e-10 -61.6640890459077 28.6151166667023 -2.15494802150021 0.0320436421366465 FRA10AC1 other 1.0901749498445e-10 1 1.13774341461358e-05 6.35410564130778 -2.15494802150021 0.116388615296377 111.533970724628 281.820126073826 0.39576297221374 0.69259128162738 -588.654419197468 399.784148236032 -1.47243061485752 0.14206503589102 ADD3 other 1 1 1 0.39576297221374 -1.47243061485752 0.158306979509766 62.0297696245735 40.1643390383137 1.54439911398521 0.123650046673329 -3.76571672354944 56.5542349517285 -0.0665859369641132 0.946960078490544 HABP2 other 1 1 1 1.54439911398521 -0.0665859369641132 0.0262893210220568 12.8509146285016 6.74918940516922 1.904067860158 0.0579564856510007 -4.96239307733615 9.44535825817039 -0.525379021282077 0.599747741468808 VAX1 other 1 1 1 1.904067860158 -0.525379021282077 9.2507161197197e-22 181.049370395119 39.440985767587 4.59038654515343 6.76610009556476e-06 -293.286279299842 61.6502828226677 -4.75725764541027 3.18875290424105e-06 DNAJB12 other 1.38085439519056e-17 0.0495372763673847 0.0704554002951159 4.59038654515343 -4.75725764541027 1.24452013641337e-09 635.498949571267 167.073828850184 3.80370135732702 0.000176065483491381 -488.796007555479 262.293881333106 -1.86354330902108 0.063463386568096 EIF4EBP2 other 1.33785914664437e-05 1 1 3.80370135732702 -1.86354330902108 0.0760635047513349 12.2786403007027 6.81400624789921 1.80197080161003 0.0726571311042116 0.386321294329115 10.6637139076102 0.0362276499234865 0.971127411677226 NPFFR1 other 1 1 1 1.80197080161003 0.0362276499234865 0.140877128478756 22.6483873720138 69.8473396651968 0.32425554760676 0.745992869797362 -140.280017064846 98.3500028323775 -1.4263346520074 0.154914317432482 PLEKHS1 other 1 1 1 0.32425554760676 -1.4263346520074 1.75620917061119e-06 60.5335665529012 38.4050625668368 1.57618716145961 0.116140743884522 -175.201126279863 54.0770490376755 -3.23984258382517 0.00134404995543013 TCF7L2 other 0.01534399952363 1 1 1.57618716145961 -3.23984258382517 0.000114563562452703 1117.909823235 304.841302326266 3.66718622018785 0.000294924491891318 125.933716383099 421.843648437591 0.298531735275682 0.765525293360399 MKI67 other 0.842615001839627 1 1 3.66718622018785 0.298531735275682 0.35137563817801 90.6564191288462 84.6621651425989 1.07080203980315 0.285207685343049 -25.5383640831745 128.396235157733 -0.198902748603189 0.842487414797222 INA other 1 1 1 1.07080203980315 -0.198902748603189 8.60943815220367e-06 128.271081136607 27.7963999307099 4.61466526083801 6.15866779324659e-06 57.4096644162171 38.8300024381578 1.47848727302168 0.140474037852583 FUOM other 0.0709073326215494 1 0.0643026504292876 4.61466526083801 1.47848727302168 0.00371614043933193 21.249004991355 16.8422647392726 1.26164772495274 0.208176661037451 -39.8433731336792 23.3460523499871 -1.70664284206924 0.0890511324087771 LRRC27 other 1 1 1 1.26164772495274 -1.70664284206924 2.49249774755653e-13 293.371572248807 53.3915224958687 5.49472198084457 9.29519025985251e-08 -98.3219854194972 75.0215745262639 -1.31058280288527 0.191150827311899 MTG1 other 3.13780541439892e-09 1 0.00110129414198733 5.49472198084457 -1.31058280288527 3.4842593613347e-07 36.8030557305108 8.76000206158114 4.20126108096692 3.62195413982606e-05 -3.94464739226707 12.2362031287831 -0.322375115119501 0.747420813275777 NKX6-2 other 0.0032229399092346 1 0.354661749371768 4.20126108096692 -0.322375115119501 1.85045879319588e-05 26.4640621187566 10.1765783502533 2.60048723725473 0.00983986753654654 -22.4926751938216 14.2993287218017 -1.57298818926568 0.116932956299487 PAOX other 0.148147730983262 1 1 2.60048723725473 -1.57298818926568 0.000739924498792169 892.622095043044 233.140794778189 3.82868256021984 0.000159946520709006 878.324151334448 353.574707908563 2.484126074882 0.0135892291274316 GSTO1 other 1 1 1 3.82868256021984 2.484126074882 6.11375807018357e-09 55.1195964388295 11.0699833864153 4.97919414282686 1.13551557523149e-06 -7.68834045472101 16.7884224042742 -0.457954909018945 0.647350465318067 TAF5 other 6.31428933488559e-05 1 0.0125372274661309 4.97919414282686 -0.457954909018945 1.83859070041902e-08 251.401111498099 94.170469913008 2.66963849421518 0.00805004934772579 -378.915625482684 132.481266192948 -2.86014495763367 0.00456278568051 PPRC1 essential 0.000184318717717007 1 1 2.66963849421518 -2.86014495763367 0.000869355755540186 202.070698598997 99.5827637108929 2.02917343392522 0.0434143611051884 -227.117205505454 151.024391185187 -1.50384453612505 0.133781602355179 ITPRIP other 1 1 1 2.02917343392522 -1.50384453612505 1.21397633388427e-17 206.095179754431 58.9706110174371 3.49487950351219 0.000553858933007869 -477.025686461418 89.0147284644535 -5.35895232946658 1.79105342103676e-07 CNNM2 other 1.70830749704194e-13 0.00282484945565918 1 3.49487950351219 -5.35895232946658 8.79461688161777e-13 469.868399124243 91.6141918393216 5.12877306114675 5.54837049483393e-07 -277.141323774856 138.939481400866 -1.99469093291958 0.047074425066784 PDCD11 essential 1.08631107721743e-08 1 0.00625523289587578 5.12877306114675 -1.99469093291958 0.844595040355025 -60.4953296600646 150.122441449369 -0.402973260200191 0.687283290647393 -119.614207862373 207.951244150688 -0.575203136441427 0.565627683837781 ADAM12 other 1 1 1 -0.402973260200191 -0.575203136441427 1.62926619963844e-08 145.977979178699 41.2456098608156 3.53923677383618 0.000472356441741067 -130.348432478861 57.2675906133458 -2.27612915233218 0.0236215536231546 RGS10 other 0.000163822716373645 1 1 3.53923677383618 -2.27612915233218 4.02647021940016e-11 168.322394936871 49.7516038230083 3.3832556541429 0.000824587265666771 -260.443674118105 80.8448860400907 -3.22152317697561 0.00143441483123382 BTBD10 other 4.66184722002151e-07 1 1 3.3832556541429 -3.22152317697561 0.000340194430819374 1003.59344812051 337.024249635361 2.97780782601352 0.00316687700972541 -221.620553503948 525.502036134298 -0.421731103335459 0.673556874051079 ADM other 1 1 1 2.97780782601352 -0.421731103335459 0.0031146650248862 65.6256757085026 19.4729734649784 3.37009013166523 0.000861132213435221 45.8431960934775 35.7482276101854 1.28239074097245 0.200805511967256 GAS2 other 1 1 1 3.37009013166523 1.28239074097245 0.0963462356817946 15.3649920353745 12.0368963450351 1.2764911813594 0.20288285254428 -21.958705383188 23.1863386356116 -0.947053596011139 0.344461429353647 SLC5A12 other 1 1 1 1.2764911813594 -0.947053596011139 6.88796703525348e-19 293.318351453897 40.3845784438548 7.26312772737461 4.15179889977233e-12 -195.221775956457 78.0245566240491 -2.50205556305955 0.012946081608368 LIN7C other 9.90902937691565e-15 1 5.76726385167375e-08 7.26312772737461 -2.50205556305955 0.560630314107469 0.206391185194376 6.10034838421249 0.0338326882655603 0.973036428596376 -12.5187739420391 13.1819495548078 -0.949690627322514 0.343148016201402 LRRC4C other 1 1 1 0.0338326882655603 -0.949690627322514 2.34784693346345e-11 50.9148576345616 7.83466164614086 6.49866706874838 4.04177541782917e-10 0.435481870284918 15.5100043882649 0.0280774820808181 0.977621647135842 IMMP1L other 2.74298957236535e-07 1 5.29593832998156e-06 6.49866706874838 0.0280774820808181 0.51296470293003 -6.80451203830756 6.29774057818549 -1.08046877349592 0.280890561290534 -11.3117417625116 12.019327367637 -0.941129350796237 0.347473646942745 SAA4 other 1 1 1 -1.08046877349592 -0.941129350796237 3.43563830825485e-18 205.17183099753 41.6699124844602 4.92374038640096 1.48043455520752e-06 -217.722294182198 62.3580352667403 -3.49148739614514 0.000560942170145604 PGAP2 other 4.88375985518427e-14 1 0.0162196409868536 4.92374038640096 -3.49148739614514 1.1471434327496e-08 124.4541889426 29.8893545655459 4.16382992378365 4.22717705221527e-05 -188.576249319718 61.0382360448825 -3.08947737580513 0.00221684036494045 TUT1 essential 0.00011641211555543 1 0.411346598951068 4.16382992378365 -3.08947737580513 0.934969539057809 593.985914101363 1675.26582253322 0.354562187153785 0.723196440157694 105.901821844956 3421.27763113922 0.0309538813456928 0.97532935843545 SCGB1A1 other 1 1 1 0.354562187153785 0.0309538813456928 0.455428732708018 -186.8668600197 215.501659785488 -0.867124922405279 0.386635080428706 -398.926233993652 317.728719103257 -1.25555610811501 0.210350520848432 SYT8 other 1 1 1 -0.867124922405279 -1.25555610811501 0.0104941834088425 9.22392980977997 3.75775870453199 2.45463600381142 0.0147270989771684 0.211121552869509 5.91381463720309 0.0356997244285218 0.971547879363977 ZNF214 other 1 1 1 2.45463600381142 0.0356997244285218 0.00198810045539636 20.0264049142803 7.12806775266014 2.80951382747542 0.00532033394031907 -0.905604322844421 11.2025092181206 -0.0808394177778996 0.935628890875311 ZNF215 other 1 1 1 2.80951382747542 -0.0808394177778996 1.59215362739506e-09 352.656658943835 90.2740030920563 3.9065140224724 0.000119338692070952 -560.025820883601 186.197375875864 -3.00769985747255 0.00288936656532109 HSD17B12 other 1.70169379695984e-05 1 1 3.9065140224724 -3.00769985747255 1.49496017154165e-11 59.1516446178434 13.3859371676815 4.41893935978252 1.43763822328535e-05 -103.812136064083 30.7038578147825 -3.3810779313244 0.000828774240450624 APIP other 1.76255804224761e-07 1 0.145661504783272 4.41893935978252 -3.3810779313244 0.864404710280848 2.54243415070458 50.4127794320689 0.0504323344070029 0.95981586166252 58.9279782958049 116.310872222091 0.506642046181926 0.612827277750928 PAMR1 other 1 1 1 0.0504323344070029 0.506642046181926 7.43071457073061e-08 262.147589402014 71.894500712004 3.6462815209209 0.000319791178604827 -384.337938762393 154.785900501118 -2.48302938134611 0.0136415770375116 DGKZ other 0.000717361184658333 1 1 3.6462815209209 -2.48302938134611 7.68212357565835e-32 1273.97710079738 117.396310109043 10.8519347806933 6.26959427051266e-23 -718.789006593744 261.355953843198 -2.75023008285851 0.00636708740545039 EIF3M essential 1.20762982609349e-27 1 9.72852942955449e-19 10.8519347806933 -2.75023008285851 0.00147040528534181 583.659508432605 298.093717139535 1.95797319726601 0.0512553242651788 -1716.36166343194 787.792253835489 -2.17869832443207 0.0302126052413242 TNKS1BP1 other 1 1 1 1.95797319726601 -2.17869832443207 0.193662588204174 -855.459911017007 582.998721202596 -1.46734440386488 0.143441955712535 727.727439259857 1515.46801846114 0.480199799926372 0.631472702707726 SERPING1 other 1 1 1 -1.46734440386488 0.480199799926372 6.6425228357899e-15 1707.84557169981 213.427370146439 8.00199885576069 3.5979643400194e-14 -37.5788166062928 563.197099791556 -0.0667240946734298 0.946850551026164 SSRP1 essential 8.75883061127256e-11 1 5.19582030342201e-10 8.00199885576069 -0.0667240946734298 0.114681957424736 31.560876772133 17.6146109148453 1.7917441903604 0.074289555657953 -16.811943651739 45.7880584094938 -0.36716873865639 0.713779707516518 SLC43A1 other 1 1 1 1.7917441903604 -0.36716873865639 5.43962025519301e-05 28.0858677361029 43.0887047777149 0.651815084277694 0.515081149227636 -344.77352339824 92.0443865627747 -3.74573112248516 0.000220380787421712 PTPRJ other 0.415097421673778 1 1 0.651815084277694 -3.74573112248516 7.39399150708767e-08 156.181567458682 36.8422196393412 4.23920081329484 3.08988981984375e-05 -140.956014560191 79.0048475295137 -1.78414387177361 0.0755315725196445 C11orf49 other 0.000713963819924385 1 0.304477742847403 4.23920081329484 -1.78414387177361 3.61722539576418e-20 375.864126622156 62.2176012572636 6.04112211057439 5.07620622857779e-09 -632.290427818079 132.571283813406 -4.76943731425295 3.03160040473505e-06 ARFGAP2 other 5.2981500371758e-16 0.0471110702895827 6.38282171181372e-05 6.04112211057439 -4.76943731425295 2.67696427292246e-10 529.62731627789 104.995708353738 5.04427585262376 8.34912944255789e-07 -449.213877710145 224.713656350855 -1.99905019127439 0.0466014443723384 CELF1 other 2.98347668217209e-06 1 0.00930677458961928 5.04427585262376 -1.99905019127439 1.05801370781865e-15 118.074315200222 20.1149066574376 5.86999070943059 1.27938885641532e-08 -129.98105666904 41.3227448364839 -3.14550877932677 0.00184406834716458 HIKESHI other 1.42419225209469e-11 1 0.000158132462652934 5.86999070943059 -3.14550877932677 0.0851599223918213 5.24838024153835 2.66600501160633 1.96863104858759 0.0500220628794256 10.0969263463432 5.47686582411562 1.84355919436344 0.0663472803510143 CCDC81 other 1 1 1 1.96863104858759 1.84355919436344 1.00507515427575e-06 1868.92354730167 515.824758888856 3.62317534219866 0.000348062742032538 -1421.26149378802 920.131036662748 -1.54462944641324 0.123615893665671 SESN3 other 0.00894516887305416 1 1 3.62317534219866 -1.54462944641324 1.25867942500439e-06 209.792909602691 137.74786584636 1.52302112496384 0.128932491491113 -884.190286495406 245.715399300177 -3.59843253216393 0.000381203121443827 ENDOD1 other 0.0111204327199138 1 1 1.52302112496384 -3.59843253216393 0.000991490910588581 70.5259541708687 27.6303674221891 2.55247978042563 0.0112488457827169 -51.9229752371618 49.2529657708943 -1.05421012571481 0.292732681794012 CCDC82 other 1 1 1 2.55247978042563 -1.05421012571481 0.0769650468572439 2.94214286772544 9.03375583688295 0.325683239712244 0.744915352187834 -41.9534027942397 21.623049837952 -1.94021671820802 0.0533905831302308 KLHL35 other 1 1 1 0.325683239712244 -1.94021671820802 0.0226635657740466 97.2389465919587 76.995920309869 1.26291037499937 0.207710947559234 -344.244773194647 194.3138778833 -1.77159128799535 0.077590352371492 TENM4 other 1 1 1 1.26291037499937 -1.77159128799535 7.05989376743449e-10 3014.92374768129 499.978427619654 6.03010766291465 5.34704091843084e-09 -447.152642096158 1191.93738244319 -0.375147762527257 0.707844012614215 SERPINH1 other 7.6952842065036e-06 1 6.71588339354913e-05 6.03010766291465 -0.375147762527257 0.00523302358492512 40.2852468378694 32.9069300963061 1.22421771705746 0.221933303765572 -195.171428606595 83.9598556755078 -2.32458032516043 0.0208335967879553 CAPN5 other 1 1 1 1.22421771705746 -2.32458032516043 3.31168283857283e-22 168.671590952305 17.7892511272757 9.48165775757055 1.3283475813021e-18 -60.1237982793368 45.2897003092109 -1.32753800243427 0.185447980176801 INTS4 essential 4.96653075300767e-18 1 2.01616595890032e-14 9.48165775757055 -1.32753800243427 2.29468768001298e-07 793.158413131958 158.478613527298 5.00482932982838 1.00757000159661e-06 -211.654835862575 400.357721814321 -0.52866430277255 0.597471039014201 PAK1 other 0.00214690979342015 1 0.0111719361777033 5.00482932982838 -0.52866430277255 1.14599596936334e-14 7838.13736962189 1115.12678452583 7.02892036886624 1.68904335335241e-11 -4358.0150749674 2669.14918587803 -1.6327356664906 0.103685920671018 RPS3 essential 1.5010255206721e-10 1 2.30926007270342e-07 7.02892036886624 -1.6327356664906 0.00758101732444645 30.9364750507054 25.7817137314816 1.19993866090171 0.231211116709441 -88.7128680041884 46.3439181207334 -1.91422891290885 0.0566439807946526 ZC3H12C other 1 1 1 1.19993866090171 -1.91422891290885 2.35029645761611e-07 48.2073356378697 13.5990182328497 3.54491293506912 0.000461936460232883 -44.8618842860621 24.0393323351346 -1.86618678341971 0.063087421460499 TTC12 other 0.00219682209893377 1 1 3.54491293506912 -1.86618678341971 0.17087939013067 160.254707173386 90.95131330391 1.76198343214574 0.0791953745771603 60.0261984521196 160.900545114379 0.373063984397621 0.709391385590874 NCAM1 other 1 1 1 1.76198343214574 0.373063984397621 0.256454252395559 22.7629747250483 15.3487376842081 1.48305190911358 0.139214109820177 4.66801004253084 27.1323561596669 0.172045878178099 0.863528928390078 DRD2 other 1 1 1 1.48305190911358 0.172045878178099 0.000169759946870734 -6.44486856895042 15.4545648563529 -0.417020383870668 0.676993644156402 -103.459705319054 27.3974725248096 -3.7762499889494 0.000195688619047319 C11orf52 other 1 1 1 -0.417020383870668 -3.7762499889494 4.11561730433978e-11 123.849971261 21.0235402197724 5.8910140711944 1.14322120068094e-08 -27.6520892973735 37.0141743677164 -0.747067569916986 0.455675261114046 NPAT essential 4.76259234458199e-07 1 0.000141610810128347 5.8910140711944 -0.747067569916986 0.00699221438579329 117.474081886617 52.6020371511422 2.2332610721725 0.0263543267099865 -80.3194967605851 92.6114705161943 -0.867273743877549 0.386565013876548 ATM ts 1 1 1 2.2332610721725 -0.867273743877549 2.46564246259731e-28 419.02840405784 34.6916163637147 12.0786647605188 3.66425745229683e-27 30.0694859452701 76.1799390962699 0.394716592084312 0.693362525952986 AASDHPPT essential 3.83629310755515e-24 1 5.75325062585125e-23 12.0786647605188 0.394716592084312 0.0140599982223714 121.603464281706 42.5456563770609 2.8581875245735 0.00461830397712783 61.8002626236107 77.5877170352772 0.796521214762792 0.426481885656568 GLB1L2 other 1 1 1 2.8581875245735 0.796521214762792 2.21431150946021e-10 74.7450066328734 13.3537264523317 5.59731449492304 5.50135395898472e-08 -107.757038380062 47.5734937776717 -2.26506463627939 0.0243288499318695 SLX4IP other 2.47870030368975e-06 1 0.000659612339682268 5.59731449492304 -2.26506463627939 2.93749630909963e-14 492.884971328261 74.9931416616173 6.57240062767669 2.630429386598e-10 -498.174002455529 193.734047730647 -2.57143237490269 0.0106759025699788 LAMTOR1 other 3.8064077173313e-10 1 3.46716897447482e-06 6.57240062767669 -2.57143237490269 0.000641110987199109 17.0308434018209 7.54135349749033 2.25832715672175 0.0247206910070886 -40.2462731528362 19.9536107678096 -2.01699199313661 0.044682353175307 P4HA3 other 1 1 1 2.25832715672175 -2.01699199313661 0.186883098502001 7.64325494762139 4.16062382312794 1.83704542216345 0.0672901334714397 6.93520745856192 7.52276172743724 0.92189646699398 0.357396571750575 GRIK4 other 1 1 1 1.83704542216345 0.92189646699398 1.18462905570218e-06 1398.3103438279 430.800253235183 3.24584382977261 0.00131875563683671 -1572.08661523404 790.257752642868 -1.98933399890921 0.0476732447814313 ST14 other 0.0104922595463542 1 1 3.24584382977261 -1.98933399890921 2.217076474455e-08 1703.91134399143 453.817011899198 3.75462201573418 0.000212461082742499 -1797.46830435685 815.650179181372 -2.20372452582661 0.0283848238083813 HYOU1 essential 0.000221086866032652 1 1 3.75462201573418 -2.20372452582661 0.934616733753748 6.32120736052053 19.7621985168178 0.319863569589241 0.749321905293488 -4.89098989980893 64.6274070712992 -0.075679810183519 0.939730512599513 GGTLC1 other 1 1 1 0.319863569589241 -0.075679810183519 0.185201254305654 12.6733435353466 7.81186826607769 1.62231915640199 0.105893499887025 -14.9008628845733 28.0491029023184 -0.531242048505648 0.595684596509814 ADAM33 other 1 1 1 1.62231915640199 -0.531242048505648 1.86929278233264e-22 191.618429662743 19.5572849644768 9.7978032232384 1.37004714663358e-19 -141.913577777941 65.796585515242 -2.15685322675394 0.0318998226794992 KAT14 other 2.8091731932895e-18 1 2.09315803062678e-15 9.7978032232384 -2.15685322675394 1.30629529661009e-08 194.943414718515 68.7428573528972 2.83583520128872 0.00491650708430846 -598.277344473866 144.133273163087 -4.15086212464566 4.44438454837401e-05 TKFC other 0.000132079517440246 0.672213162941569 1 2.83583520128872 -4.15086212464566 1.56623280937131e-07 498.699668338243 143.687849606505 3.47071564995895 0.000604808703189059 -953.519042691499 293.443595107714 -3.24941167089196 0.00130407666221313 MTA2 other 0.00148071649797963 1 1 3.47071564995895 -3.24941167089196 1.13070261532768e-06 19.8504655386127 32.0033349156197 0.620262406744506 0.535608198289679 -318.583932843842 67.1014501163788 -4.74779505198917 3.34087548807907e-06 TMEM138 other 0.0100304629005718 0.0518904780808441 1 0.620262406744506 -4.74779505198917 0.0288423905224223 1.44378998036607 5.4659607530343 0.264142032041592 0.791872728358891 -27.2748495788207 11.1632355125778 -2.44327458182619 0.015197968680408 ROM1 other 1 1 1 0.264142032041592 -2.44327458182619 0.00829941544854392 34.5908543922984 52.5466094952965 0.658288988091508 0.510915444228078 -287.898435619735 107.316939086659 -2.68269332008487 0.00775544206174338 EML3 other 1 1 1 0.658288988091508 -2.68269332008487 2.21450239047755e-05 232.244685823669 58.7751964049892 3.9514063759718 9.92514852404734e-05 -133.185380092785 120.246557309518 -1.10760243846286 0.269019284259694 INCENP essential 0.17607508506687 1 0.931772943437564 3.9514063759718 -1.10760243846286 0.0127259619054009 -19.6224447866591 130.231064294723 -0.150674072218683 0.8803465948676 -541.56608230661 207.560749154964 -2.60919313748613 0.0095874105245592 PLCH2 other 1 1 1 -0.150674072218683 -2.60919313748613 2.92952283120899e-09 456.018910630837 103.048881299335 4.4252679396509 1.39890477801134e-05 -621.279140706129 211.203863578736 -2.94160878583794 0.00354838154668939 CPSF7 other 3.08332277984746e-05 1 0.14190490068147 4.4252679396509 -2.94160878583794 0.424666981391427 -16.4974963683954 12.5934774194497 -1.31000325159723 0.191295951611432 -15.0433683886386 29.7119575075297 -0.506306876106238 0.613049864045625 MS4A2 other 1 1 1 -1.31000325159723 -0.506306876106238 0.00447274213491897 124.346934574704 51.3965600818965 2.41936297636586 0.0162112966843593 -145.34338146811 104.968171315913 -1.38464240775123 0.167309245401532 B3GAT3 other 1 1 1 2.41936297636586 -1.38464240775123 6.25359014288188e-25 1203.1698011338 134.421027355184 8.9507558810322 5.65740043066827e-17 -538.077425171056 244.087291649727 -2.20444670238389 0.028330344799055 EI24 other 9.57299579072359e-21 1 8.46629974449507e-13 8.9507558810322 -2.20444670238389 3.04648716194069e-06 19.6805176791424 4.6942397989777 4.19248238733529 3.73559760615309e-05 -4.44871403046831 8.46640155016859 -0.525455118577469 0.599694924448412 CCDC15 other 0.026041372260269 1 0.365192021977526 4.19248238733529 -0.525455118577469 5.06818430439734e-11 235.448767956138 36.1991791392629 6.50425710070209 3.7291166486863e-10 32.8398824402476 64.9495065798147 0.505621738633096 0.613531707759358 CHEK1 essential 5.84615059512233e-07 1 4.89148230808182e-06 6.50425710070209 0.505621738633096 0.0037990013465912 161.752362098442 65.7674916211568 2.45945767599274 0.0145373798164241 -95.4197236469802 119.423346363713 -0.799003934761398 0.424985266256339 FEZ1 other 1 1 1 2.45945767599274 -0.799003934761398 0.181400933060203 200.782199532039 115.062377509738 1.74498566670975 0.0821167253035869 67.2953198445017 206.059374846048 0.326582179989528 0.744235076429074 ESAM other 1 1 1 1.74498566670975 0.326582179989528 0.616864317630506 -4.24180222225239 11.3085162327816 -0.375098035404158 0.70787987237529 12.3514545528546 20.4757213617786 0.603224391200728 0.546862086281276 KIRREL3 other 1 1 1 -0.375098035404158 0.603224391200728 4.07812961594771e-05 363.878925412335 335.710892781796 1.08390562604964 0.279373585795062 -1959.5092933384 600.365292164488 -3.26386171704533 0.00124069174927831 MPZL2 other 0.31507629412812 1 1 1.08390562604964 -3.26386171704533 0.214410120896826 8.59604465216885 5.14379359453181 1.67114883095368 0.0958508916152326 3.53393517011272 9.19885297324012 0.384171285310581 0.701153878150972 SCN2B other 1 1 1 1.67114883095368 0.384171285310581 2.45355302227013e-05 120.044163243403 72.7919346111145 1.64914099185206 0.100268933148611 -360.398078452379 126.288834265657 -2.85376043375503 0.00465148250941905 SIDT2 other 0.194026973001122 1 1 1.64914099185206 -2.85376043375503 6.3801866717255e-05 75.5480395619923 32.0213440121641 2.35930258059417 0.0190215689293135 -116.448217860087 56.8428156100314 -2.04860045390743 0.0414680043820074 TMEM25 other 0.484000960917096 1 1 2.35930258059417 -2.04860045390743 0.221026425740842 -751.97206065109 507.19465283574 -1.48261038724835 0.139331384528196 -1374.94218260999 879.946683579695 -1.56252896711493 0.11932186143255 TAGLN other 1 1 1 -1.48261038724835 -1.56252896711493 0.903868314932455 2.28178823562533 5.20780839273063 0.438147501511458 0.66162711963747 3.81049249329567 17.9548048690124 0.212226895312689 0.832088973935273 JPH2 other 1 1 1 0.438147501511458 0.212226895312689 0.00338168994816929 9.04187949245373 2.73270928519233 3.30876011636098 0.00107279301270204 -2.35210321954385 12.3820320465905 -0.189961002418138 0.849491412148379 DUSP15 other 1 1 1 3.30876011636098 -0.189961002418138 7.45715646384045e-15 340.613385554474 41.7269546374209 8.16291024624669 1.31775063058981e-14 -180.054151017749 203.136435600125 -0.886370534590784 0.376218527010089 COMMD7 other 9.81585505335318e-11 1 1.91653651712982e-10 8.16291024624669 -0.886370534590784 0.225122399090216 -6.98455712561938 5.09489833472019 -1.37089234499965 0.171546977509831 -25.1903202195232 18.2729155883122 -1.3785605311741 0.169171418551952 KIAA1755 other 1 1 1 -1.37089234499965 -1.3785605311741 1.15674362671016e-20 220.212657965299 22.333525741114 9.86018331892431 9.07350185184102e-20 -77.9764975891883 88.3654033368703 -0.882432429940064 0.378333805424648 DSN1 essential 1.70480875704543e-16 1 1.38761063820205e-15 9.86018331892431 -0.882432429940064 8.47531558747371e-07 567.474203653109 112.052592595147 5.06435585746264 7.61677164473782e-07 -242.522383533823 441.296525505925 -0.549567851810714 0.583071768921558 SOGA1 other 0.00758625498234772 1 0.00851326566732346 5.06435585746264 -0.549567851810714 2.15781779214718e-08 18.8531831872375 3.51266806738089 5.36719747655941 1.73245298267816e-07 -23.2887605446463 14.7192313269605 -1.58219950670857 0.114783415586422 CNBD2 other 0.00021537179383421 1 0.00201952044190793 5.36719747655941 -1.58219950670857 0.000289892833317072 61.6352710582084 15.9453590104194 3.86540503841481 0.000139101445872032 -10.0557097208868 52.867092506709 -0.190207352893687 0.849290107809351 CDH22 other 1 1 1 3.86540503841481 -0.190207352893687 7.60914915687154e-18 560.375327061795 60.4549055742503 9.26931109624423 6.07259594446105e-18 75.438155054129 171.504819397681 0.439860263513674 0.660388899904277 LSM14B other 1.07524886735752e-13 1 9.16840535694729e-14 9.26931109624423 0.439860263513674 6.10468441313263e-16 336.906815282754 43.9302133347369 7.6691367901087 3.08975421858289e-13 -292.345883192614 122.992140837824 -2.37694767487704 0.0181485847257657 YTHDF1 other 8.26757410070553e-12 1 4.40289976148062e-09 7.6691367901087 -2.37694767487704 6.41002022342267e-07 120.258459964292 22.3333347262444 5.38470682674064 1.57415809435915e-07 36.8836542703448 62.7518850317615 0.58776966224483 0.557176354651359 CABLES2 other 0.00579658128804112 1 0.00184034822811528 5.38470682674064 0.58776966224483 7.10788839796754e-09 269.993472709421 46.8820810235872 5.75899078740943 2.64627145091918e-08 -149.633227537408 157.867076513862 -0.947843152870883 0.344187121968289 ORAOV1 essential 7.30477690659124e-05 1 0.000321945384718828 5.75899078740943 -0.947843152870883 8.64527438325785e-08 104.233535092795 24.5715314152025 4.24204471961829 3.03625231294847e-05 -134.789817081311 54.1514668480897 -2.48912587094705 0.0134016834394532 TRPT1 other 0.000830897320974912 1 0.299475119857202 4.24204471961829 -2.48912587094705 4.13037514305811e-10 104.532769593663 30.4841275014029 3.42908845230528 0.000699164554290738 -302.687275802215 67.1818207783267 -4.50549378232786 9.82782471831798e-06 NUDT22 other 4.55952112042185e-06 0.15121091111604 1 3.42908845230528 -4.50549378232786 0.393068926629002 -82.7014753660598 60.8717921264003 -1.35861739037238 0.175389374980123 -37.2744625929057 134.151053819834 -0.27785441509066 0.781334426095652 FERMT3 other 1 1 1 -1.35861739037238 -0.27785441509066 0.000168967632931064 212.598063999288 67.4181410188349 3.15342518773832 0.00179376897738394 -247.191828741821 148.578090907371 -1.66371654954114 0.0973165162688792 PLCB3 other 1 1 1 3.15342518773832 -1.66371654954114 2.27982489153243e-09 386.544835828321 80.6355993263622 4.79372434827241 2.70259265211286e-06 -528.187076272649 187.747039102542 -2.81329111126044 0.00526267205562235 MRPL49 other 2.41638640253522e-05 1 0.029047465824909 4.79372434827241 -2.81329111126044 0.488954536245543 6.39152256537336 34.050817328812 0.187705408174305 0.851248575675004 -84.947984619317 79.2794048698317 -1.07150129038926 0.28490092613243 CDC42EP2 other 1 1 1 0.187705408174305 -1.07150129038926 1.85245989048476e-08 1246.38921641096 259.116911670776 4.81014229590144 2.50590677350682e-06 -1350.43711599439 603.312102272409 -2.23837232985695 0.0260089971749002 FAU essential 0.000185672054823288 1 0.0269986395777625 4.81014229590144 -2.23837232985695 0.00034557931435789 118.380118405328 43.6490844903271 2.71208708699405 0.00711375545828704 -209.003472025532 101.629881107815 -2.05651595522195 0.0406901999368688 TM7SF2 other 1 1 1 2.71208708699405 -2.05651595522195 2.67301461318981e-09 329.436491499549 71.0081710061953 4.63941665911669 5.44447723782041e-06 -491.756629385797 165.331118883886 -2.97437429024578 0.00320037733722827 VPS51 essential 2.82029771837657e-05 1 0.0571288996564496 4.63941665911669 -2.97437429024578 0.000881326063118268 33.310154721679 18.683081577147 1.78290474106925 0.0757378446089035 -77.1389728693656 37.3722513859083 -2.06407080143028 0.0399770650626645 TBX6 other 1 1 1 1.78290474106925 -2.06407080143028 4.28684262583493e-14 619.559061935474 114.971136068083 5.38882264822179 1.55880907666891e-07 -670.353460047649 229.979737631483 -2.91483705021794 0.00386050946364535 PPP4C essential 5.5317417243774e-10 1 0.00182271545334895 5.38882264822179 -2.91483705021794 5.35613697174657e-10 8944.2752978837 1856.56350149996 4.81765115529711 2.43822627082333e-06 -6877.78161123954 3713.73199894543 -1.85198652277348 0.0651315576752531 ALDOA essential 5.87300418952011e-06 1 0.0262865174257463 4.81765115529711 -1.85198652277348 2.15311948105727e-07 50.7787901260726 14.5895712730944 3.48048542178324 0.000584427786207253 -64.6024622075113 29.140385390163 -2.21693918397247 0.0274698633149111 DOC2A other 0.00201854951349119 1 1 3.48048542178324 -2.21693918397247 1.09043740402337e-15 172.470706642652 28.2145059638931 6.11283808631518 3.45614852477619e-09 -145.138134799124 56.3540601701667 -2.57546899657035 0.0105489856153953 HIRIP3 other 1.46761970207505e-11 1 4.37686649177657e-05 6.11283808631518 -2.57546899657035 7.23476960786362e-07 115.134744566693 65.7484004930483 1.7511413768745 0.0810742012946671 -474.502264435943 130.377016422645 -3.63946251767063 0.000328182847352165 TAOK2 other 0.00651627491505201 1 1 1.7511413768745 -3.63946251767063 0.000492324787524316 43.1508268117199 83.0008565202347 0.519884114704288 0.603576718025097 -520.01231334608 164.58809571765 -3.15947706350621 0.0017630501423997 TMEM219 other 1 1 1 0.519884114704288 -3.15947706350621 0.000171530412281947 457.197830352076 116.589070359379 3.92144674404547 0.000111679054999862 -127.423415524586 347.183028276572 -0.367020865498871 0.713890938373584 HMGA2 other 1 1 1 3.92144674404547 -0.367020865498871 0.857249979733453 17.7248017541579 99.3129005581305 0.178474313553888 0.858483838669641 120.539695244575 217.215968523134 0.554930174167822 0.579400149966338 MMP3 other 1 1 1 0.178474313553888 0.554930174167822 0.939100429207109 -1.8205585144084 38.1191858259634 -0.0477596379607982 0.961943375111816 -21.9207234341638 67.5128537945068 -0.324689628746628 0.745669281223216 CNTN5 other 1 1 1 -0.0477596379607982 -0.324689628746628 0.582220734453613 -0.411691767627336 1.82636482811918 -0.225415952655693 0.821826225463123 -8.62155502404276 8.28502273243297 -1.0406193564554 0.298983170280957 KLRF1 other 1 1 1 -0.225415952655693 -1.0406193564554 0.753229746737387 8.79046650194992 13.9293980918321 0.631072961228991 0.528524699399026 -18.1957188514766 63.2312910645775 -0.287764468273998 0.773746977300264 CLEC1A other 1 1 1 0.631072961228991 -0.287764468273998 0.509245593196812 16.3203338347182 34.0513157083617 0.479286438576895 0.632121399457058 -38.3724279685149 58.2318346048227 -0.658959626275229 0.510481201188223 MKX other 1 1 1 0.479286438576895 -0.658959626275229 2.29618158398764e-10 316.966439204189 61.9799954951807 5.11401197550644 5.95896017614837e-07 -145.040388227928 107.169556203159 -1.35337304143518 0.177060126605947 MPP7 other 2.56768244357835e-06 1 0.00670800147029022 5.11401197550644 -1.35337304143518 8.7779722995611e-10 1518.40225685987 511.87105453434 2.96637647979762 0.00328005553845331 -3184.38165957207 886.132649327793 -3.5935722061338 0.000386855803530501 ITGB1 other 9.51532197272423e-06 1 1 2.96637647979762 -3.5935722061338 0.235054011053239 24.1010448406021 23.4365230176388 1.02835411304242 0.304717467624998 -17.2053810996407 35.9662068744534 -0.478376303614646 0.632775333746464 PCDH15 other 1 1 1 1.02835411304242 -0.478376303614646 0.000151587881805935 43.3648368431634 18.776150990108 2.30957009591634 0.0216781447676901 -77.9600013404311 39.0567548946279 -1.99606960564853 0.0469457561646763 CTF1 other 1 1 1 2.30957009591634 -1.99606960564853 4.98729820546477e-17 223.596067361201 40.2018147101608 5.56184015505868 6.45691017695552e-08 -251.651243205642 71.712217778508 -3.50918227048699 0.000527043525827814 CWC15 other 6.93234450559604e-13 1 0.000770696798721411 5.56184015505868 -3.50918227048699 0.0490845647054546 37.0011515454677 17.3739386556243 2.1296927702395 0.034154894651254 78.574951772882 58.8515242142727 1.33513877205284 0.18302160439139 FCGR1A other 1 1 1 2.1296927702395 1.33513877205284 0.00151332999814896 75.1580715701238 114.349725833903 0.657264991428957 0.511570429137201 -425.439226896882 171.869576478725 -2.47536088476686 0.0139241951792602 ARID5B other 1 1 1 0.657264991428957 -2.47536088476686 0.00157230451807839 38.6538793385419 13.5843870480595 2.84546363422879 0.00477074778121397 -3.79808839831732 23.2636005368979 -0.163263136860232 0.870432049028655 CDH8 other 1 1 1 2.84546363422879 -0.163263136860232 2.52850321903723e-23 123.490514184397 13.2209027286023 9.34055084735138 4.24307172987897e-18 -46.2001899696048 24.7844704153786 -1.86407815843173 0.0634248595953478 DCUN1D2 other 3.82815387362237e-19 1 6.41594876274999e-14 9.34055084735138 -1.86407815843173 3.31528533570674e-16 370.403014184396 48.4526711505939 7.6446355874408 3.93655114908236e-13 -108.776975683891 90.8314522335885 -1.19756948731979 0.232162875018066 TMCO3 other 4.51939696963543e-12 1 5.60013766468457e-09 7.6446355874408 -1.19756948731979 3.03312608013886e-08 62.0220554540028 17.0784343178369 3.63160078375722 0.000336542478056354 -75.455981250412 30.79572422803 -2.45020966844912 0.0149076757257319 TMEM218 other 0.000300218819412145 1 1 3.63160078375722 -2.45020966844912 4.39758126400827e-06 21.3777491984742 7.43150918121985 2.87663631668489 0.00434137752188841 -30.0849824493521 13.3618621918063 -2.25155610928248 0.0251574496826638 TIRAP other 0.0371419713558138 1 1 2.87663631668489 -2.25155610928248 0.000254961778058196 20.1663825053155 9.86097151118452 2.0450705574438 0.0418585654270214 -25.6819806594739 14.8743030424391 -1.72660060684514 0.0854318038815494 EEF1AKMT1 other 1 1 1 2.0450705574438 -1.72660060684514 0.195973837416131 -22.945834489369 44.5181426600055 -0.515426590561319 0.60669124465162 -116.123918581482 67.6266882773948 -1.71713152809078 0.0871413996939079 LATS2 other 1 1 1 -0.515426590561319 -1.71713152809078 1.69862984811196e-20 693.695664236889 105.662722101344 6.56518827492963 2.7900303393363e-10 -460.489545236716 160.510289583759 -2.86890981525779 0.00445577549819629 SAP18 essential 2.49766532866383e-16 1 3.67279593870231e-06 6.56518827492963 -2.86890981525779 9.80979391035409e-06 126.970298172584 46.2317181324963 2.74638934699977 0.00644158053050886 -129.476484550288 76.676731569585 -1.68860202958425 0.0924809805299982 ADGRL3 other 0.0804599296527242 1 1 2.74638934699977 -1.68860202958425 1.65128773925555e-19 52.2277694558432 7.12949853506919 7.32558807592719 2.86714734725976e-12 -42.3370920286707 12.8603377665715 -3.29206688013434 0.00112965593843385 KIAA1328 other 2.39733953985121e-15 1 3.99852369048846e-08 7.32558807592719 -3.29206688013434 0.302049123063526 18.4457148439109 11.904385860454 1.54948899171582 0.122426924968598 15.5911263014473 19.4942625116841 0.799780258017073 0.424536031274283 FAM124A other 1 1 1 1.54948899171582 0.799780258017073 0.820261125323527 -26.2192762450734 49.6653793646719 -0.527918573873287 0.59799430869533 14.7046604317295 119.19538740957 0.123366019032284 0.901910078250363 HNMT other 1 1 1 -0.527918573873287 0.123366019032284 0.0980686440629329 -97.6601565123932 60.9384378446798 -1.60260354493021 0.110182817412443 -301.603671904101 155.553080638649 -1.93891159638766 0.0535463231773781 LYPD1 other 1 1 1 -1.60260354493021 -1.93891159638766 0.051239682082044 25.4831975560082 46.1247090097595 0.552484733304577 0.581075059219371 -218.436776507041 107.699879621246 -2.02819889191361 0.0435252704617685 LYPD6B other 1 1 1 0.552484733304577 -2.02819889191361 0.299376462267478 8.80990003224771 38.9155559588275 0.226385048733944 0.8210726135686 -63.5649790390197 55.3115433180721 -1.14921723795494 0.251479664077834 ADRA2A other 1 1 1 0.226385048733944 -1.14921723795494 0.00587806442535352 34.4387821834721 45.6913215795022 0.753726987816474 0.451667531097245 -138.978891471404 67.8525841926133 -2.04824758150528 0.0414992343738595 GPM6A other 1 1 1 0.753726987816474 -2.04824758150528 0.00603417076281683 23.5338270968796 9.75909847539237 2.41147552268484 0.0165509648260622 -3.39677008746927 14.4718752720238 -0.234715268313271 0.814606328282736 WDR17 other 1 1 1 2.41147552268484 -0.234715268313271 0.0417206612107738 36.0158548653244 29.5565168092351 1.21854192419829 0.224073926512377 -44.9728154667349 43.5759405058029 -1.03205610584001 0.302962612702634 VEGFC other 1 1 1 1.21854192419829 -1.03205610584001 0.0024187113939198 14.1286767114314 14.1127832163749 1.0011261772262 0.317665504710032 -53.1861447756305 23.0694874098194 -2.30547579279946 0.0219010375346881 CCDC102B other 1 1 1 1.0011261772262 -2.30547579279946 0.0321735648868259 -11.5886257268601 10.463163612208 -1.10756422783439 0.269039424999531 -44.7714301380489 17.1259581983974 -2.61424380577074 0.00944655583112983 CD226 other 1 1 1 -1.10756422783439 -2.61424380577074 0.629431203231807 5.16531749369203 31.9173713604087 0.161834050660552 0.871557575778961 -53.4026230025234 68.8580299687665 -0.775546773945557 0.438695380286749 DLG2 other 1 1 1 0.161834050660552 -0.775546773945557 0.570173609586573 -3.47448285624603 4.2538909109392 -0.816777611130351 0.414791958698505 7.4373580585799 11.9802189279658 0.620803184257232 0.535264713485991 RGS18 other 1 1 1 -0.816777611130351 0.620803184257232 0.101505930367462 289.432739914476 276.814990866209 1.04558188488558 0.29669274868954 -659.673649017649 567.658459443107 -1.1620960421603 0.246226462455677 PRSS23 other 1 1 1 1.04558188488558 -1.1620960421603 5.27252279983945e-26 334.309977337235 28.5504157334228 11.7094609219953 9.44981466830632e-26 -228.957235896883 187.803132289376 -1.21913427697305 0.223889690680453 MTMR12 other 8.12337587771264e-22 1 1.47927398817667e-21 11.7094609219953 -1.21913427697305 0.234332007206781 -3.88167877252372 5.63316089180679 -0.689076496673381 0.491362500635167 -25.7106252842616 15.0942478710125 -1.70333927890751 0.0896468104142815 PPP1R1C other 1 1 1 -0.689076496673381 -1.70333927890751 0.0580615484171084 34.5663272809897 21.1657857064524 1.63312280301752 0.10360443270673 -26.4261129404842 38.0465569495115 -0.694573045743724 0.487917943370597 C11orf53 other 1 1 1 1.63312280301752 -0.694573045743724 1.02439952841012e-27 2283.8903759348 181.859061288037 12.5585734346086 8.86854824060011e-29 1747.27390779696 1141.49294714316 1.53069181213068 0.12702069267729 CCT5 essential 1.59048270780955e-23 1 1.39608686403527e-24 12.5585734346086 1.53069181213068 2.71392001143573e-17 70.6107327533347 7.56361978780534 9.335574068276 3.92727199024353e-18 -12.9742547227531 47.4753283201965 -0.273284149511269 0.784844495110289 FAM173B other 3.79487435199059e-13 1 5.94078433964139e-14 9.335574068276 -0.273284149511269 9.4684751540845e-10 11.7085922441845 88.6076828243058 0.132139695689828 0.894971134825293 -659.762326768301 122.740329205467 -5.37526932703483 1.64180999850104e-07 DOCK1 other 1.0240103274896e-05 0.00259061199663479 1 0.132139695689828 -5.37526932703483 0.291672845304239 34.5714440583581 27.480774068593 1.25802293530985 0.209466315476492 -5.82491075317272 48.7172404724989 -0.119565695771724 0.904915783450584 DIXDC1 other 1 1 1 1.25802293530985 -0.119565695771724 1.01298398530919e-23 428.941945818571 47.1761524946752 9.09234694090379 2.1269708603344e-17 -73.5662385481624 83.6327230053183 -0.879634620332573 0.379836611458802 DLAT other 1.53831748009054e-19 1 3.19598641473847e-13 9.09234694090379 -0.879634620332573 0.000290905569640167 13.7584287613472 4.10935328616214 3.34807640114016 0.000929090150576764 -1.37434408099068 7.28496045012116 -0.188654981780693 0.850504436476097 PIH1D2 other 1 1 1 3.34807640114016 -0.188654981780693 1.27262540607572e-07 234.733954114674 62.2295175391504 3.77206771636942 0.000198831122385068 -186.303323196187 110.318958369778 -1.68876978127111 0.0924137921536914 TIMM8B other 0.00121001223609679 1 1 3.77206771636942 -1.68876978127111 0.0142507785183057 21.4497555102907 43.4396725993716 0.493782623734622 0.621859662039366 -167.588667697498 77.0087833329567 -2.17622796315205 0.0304019360564114 IL18 other 1 1 1 0.493782623734622 -2.17622796315205 1.22732483065716e-08 150.383643438718 37.6520393001203 3.99403714205296 8.37351939930389e-05 -126.622723183634 66.7486093472279 -1.89700915752326 0.05888983420521 PTS other 0.000124328005345571 1 0.791632524010189 3.99403714205296 -1.89700915752326 0.00478025187848018 108.973069652086 53.1458575735812 2.0504527469749 0.0412821376860662 -89.3963644825234 88.9150438611169 -1.00541326417336 0.31559476501847 PIP4K2A other 1 1 1 2.0504527469749 -1.00541326417336 0.0338000427843841 183.317355639994 175.768139032941 1.04294985796964 0.297897580443928 -426.967414287947 274.228964814807 -1.55697416783194 0.120639356911279 FREM2 other 1 1 1 1.04294985796964 -1.55697416783194 0.0531160092363511 62.6540133294698 58.0484768538501 1.07933948873827 0.281389082290086 -123.061301834708 92.4409343818636 -1.33124251347736 0.1842198325335 FOXO1 og 1 1 1 1.07933948873827 -1.33124251347736 0.0199736367909321 251.450082164033 108.714129167061 2.3129475817962 0.0214718436699796 698.046014325066 409.165322349759 1.70602437742358 0.0891450183100573 CRIM1 other 1 1 1 2.3129475817962 1.70602437742358 0.00046775727614421 164.378746709687 105.241113316174 1.56192519757794 0.119476917615808 -318.831451133567 157.055117827977 -2.03006088272006 0.0433306714269644 SEC24D other 1 1 1 1.56192519757794 -2.03006088272006 4.8478769144888e-11 169.162794193593 28.1279738371353 6.01404122362558 5.81322212826576e-09 -121.507116169343 58.3408241217309 -2.08271168600246 0.0382117651000615 ABCB9 other 5.59590432239442e-07 1 7.28978054884526e-05 6.01404122362558 -2.08271168600246 0.133432308199383 50.7936252161608 33.285999151983 1.52597568077312 0.12817783953767 -60.014934758686 69.3272596168432 -0.86567585521735 0.387430842712418 RILPL2 other 1 1 1 1.52597568077312 -0.86567585521735 2.75595068205436e-10 205.428008837096 35.4533255316662 5.79432269770043 1.89367737527156e-08 -146.990325794339 72.4277526601886 -2.0294751720929 0.0433834322624924 DHX37 essential 3.06930227460394e-06 1 0.00023186185782825 5.79432269770043 -2.0294751720929 0.134619262406922 788.831438826408 2190.69461864245 0.360082793883539 0.719064656283492 -8064.79862099034 4475.37954800103 -1.80203679587189 0.0726467194081217 UBC other 1 1 1 0.360082793883539 -1.80203679587189 0.967071896764658 7.00525803716454 55.9495113416415 0.125206777846346 0.900455141336194 40.1865307244163 157.494974661548 0.255160717418293 0.798797638273571 ITPR1 other 1 1 1 0.125206777846346 0.255160717418293 6.74204484280639e-05 52.0058429750049 15.7394691980371 3.30416752437182 0.00108335214479195 -31.4079210196576 32.4814892207282 -0.966948307272023 0.334448191555947 PRSS53 other 0.509833431013019 1 1 3.30416752437182 -0.966948307272023 0.000337581541206257 1772.78727630903 441.137476652024 4.01867302176058 7.58887689490113e-05 1305.87321478825 650.31769142747 2.00805426640295 0.0456298037060618 SLC7A11 other 1 1 0.721322748860352 4.01867302176058 2.00805426640295 0.00010744542599459 55.661489376559 21.9387325659826 2.53713331930877 0.0117396872112343 -40.337735372738 32.4139966266624 -1.24445423492017 0.214411598742725 NOCT other 0.793377025544051 1 1 2.53713331930877 -1.24445423492017 0.0800339428795266 7.00038381454079 13.2884359680147 0.526802690052518 0.598759963462215 -34.1654144717274 21.9555918376624 -1.55611448438026 0.120843611699513 ENKUR other 1 1 1 0.526802690052518 -1.55611448438026 0.357512009833287 10.2911665083433 11.9026573839897 0.864610832383196 0.388014284401641 -9.697985933197 19.6659627916661 -0.493135578254359 0.622314680359539 GPR158 other 1 1 1 0.864610832383196 -0.493135578254359 0.0110662454895075 6.40962127008416 2.250734603534 2.84779078795877 0.00473953167571414 16.2824006194046 10.6364605112642 1.53081004739887 0.126982799052787 CACNA2D4 other 1 1 1 2.84779078795877 1.53081004739887 3.4007590618043e-06 54.7638025739535 10.7777338707162 5.08119825845302 6.97992519819936e-07 9.66908169660524 50.9709500041211 0.18969789057931 0.849687357904805 DCP1B other 0.0289472611340782 1 0.00781961019954274 5.08119825845302 0.18969789057931 0.276673039418841 -12.8808222109036 15.095586296264 -0.853283996931708 0.394252614712602 84.4138914713416 71.3912946468619 1.18241155156096 0.238075022590742 CACNA1C other 1 1 1 -0.853283996931708 1.18241155156096 3.80410526299909e-06 105.9119602049 38.4748124683007 2.75276092098332 0.00631021585007467 -329.722276008064 103.631387483624 -3.1816835035637 0.0016352606233897 THRB other 0.0322778331565473 1 1 2.75276092098332 -3.1816835035637 2.43907483242446e-09 145.284715403934 24.0959350460949 6.02942841296707 5.38855872026154e-09 -27.1760302469796 64.9020754447979 -0.418723593363266 0.675751038545672 NGLY1 other 2.5800533577386e-05 1 6.76749089677647e-05 6.02942841296707 -0.418723593363266 2.61616947705709e-10 64.6638965585201 9.65664808044196 6.69630870047825 1.23537447064213e-10 13.5457076884965 26.0100511169945 0.52078743050397 0.60294168372519 OXSM other 2.91702896691865e-06 1 1.64712478170715e-06 6.69630870047825 0.52078743050397 5.9251318908806e-18 101.314874882723 19.3559477080266 5.23430195260909 3.31540456185464e-07 -141.101638189547 36.941101197386 -3.81963811624357 0.000165614017466893 UEVLD other 8.38939424429785e-14 1 0.00379845900651686 5.23430195260909 -3.81963811624357 0.000924210632569871 12.2158624097318 12.7565089679664 0.957617984701596 0.339105809102379 -61.847244866104 24.3523539207267 -2.53968240883132 0.0116523361109597 TMEM86A other 1 1 1 0.957617984701596 -2.53968240883132 3.13967978256464e-09 56.3886746259059 14.2076257493722 3.96890202632186 9.24502666480281e-05 -111.299851591376 30.6424080529139 -3.63221622136162 0.000335777953335292 C12orf45 essential 3.29603583573636e-05 1 0.870234359957889 3.96890202632186 -3.63221622136162 1.01047509282496e-05 314.16834182067 70.3457137310389 4.46606232501766 1.16904889281329e-05 -90.9922845398246 156.405295360828 -0.581772403101218 0.561201838344415 TMEM263 other 0.0827275958495793 1 0.119418344400877 4.46606232501766 -0.581772403101218 0.767302791293326 40.6304629685036 63.5543416869383 0.639302711507025 0.523166036326344 -19.7866275706621 141.308757430976 -0.140024071617268 0.888744983630015 BTBD11 other 1 1 1 0.639302711507025 -0.140024071617268 5.05835770979143e-10 211.254351314027 43.4042935291756 4.86713027991172 1.9248149405138e-06 -288.6962153215 93.3793569267596 -3.091649212662 0.00219805361264298 UBE3B other 5.55660594420588e-06 1 0.0209323624780875 4.86713027991172 -3.091649212662 8.87868306109816e-06 197.739990605399 82.5152979109473 2.39640400763995 0.0172399762722553 -249.43195361646 123.748625202428 -2.01563413903338 0.0448325611489363 ANK3 other 0.0730893189589601 1 1 2.39640400763995 -2.01563413903338 2.04287412035094e-06 60.3867888394567 25.8875768109211 2.3326551295439 0.0204040346427548 -89.4647122948647 38.8677909958328 -2.30176992318541 0.0221124224424438 IPMK other 0.0177403188611276 1 1 2.3326551295439 -2.30176992318541 0.00177805628195213 4.07424704414169 1.71717287037833 2.3726481558284 0.0183593252830951 -6.88402807261309 3.66949113981909 -1.87601708528787 0.0617277535902217 RAD9B other 1 1 1 2.3726481558284 -1.87601708528787 0.00619077223989103 264.86957366321 136.824574393023 1.93583334600687 0.0539280698954232 -562.967293432203 289.033552154774 -1.94775758466526 0.0524764545341951 PLBD2 other 1 1 1 1.93583334600687 -1.94775758466526 8.74616893586584e-07 490.959162481491 230.021948794604 2.13440136932275 0.0337073858971448 -948.207204381211 353.749978604499 -2.68044455612909 0.00780295732378405 DLG5 other 0.00782257349623841 1 1 2.13440136932275 -2.68044455612909 0.237541277434858 22.1190032551352 21.2228983697077 1.04222349227787 0.298243833586988 -13.7890868784376 32.3632414264004 -0.426072490600063 0.670395749054882 MAT1A other 1 1 1 1.04222349227787 -0.426072490600063 0.280025365181272 19 18.2781247920326 1.03949394241373 0.299567460824092 -42.8160919540231 51.441792226585 -0.832321155636094 0.40601264117956 SLC2A13 other 1 1 1 1.03949394241373 -0.832321155636094 6.03478175858517e-06 85.1761546442224 22.3823355641504 3.80550789260118 0.000176361853376427 -120.21351300942 60.3955616172082 -1.99043621402749 0.047585869641794 GXYLT1 other 0.0502878363942902 1 1 3.80550789260118 -1.99043621402749 3.86080827292589e-08 498.679821816648 107.458169817056 4.64068783849226 5.48344909467956e-06 -610.515248747448 275.755093083395 -2.21397632921621 0.027688431442006 TWF1 other 0.000379363020897698 1 0.0575104141049992 4.64068783849226 -2.21397632921621 5.6320476271329e-09 106.85401459854 41.5992125195756 2.56865474432375 0.0107770778630853 -231.671717433403 71.1774650628239 -3.25484642125033 0.0012874040852958 DIP2C other 5.82353724645542e-05 1 1 2.56865474432375 -3.25484642125033 2.94442305349982e-15 220.815469162957 48.7776934699228 4.52697644055507 8.96854064205434e-06 -207.270816428044 71.9244206257355 -2.88178638944615 0.00427077290731887 EIF4E essential 3.91873264190291e-11 1 0.0924118427757279 4.52697644055507 -2.88178638944615 0.0264836027530838 73.5743995960477 46.5011406011851 1.58220634257244 0.114773123843966 -134.840719818504 97.6478120982327 -1.38088828537044 0.168455225857204 MAGI1 other 1 1 1 1.58220634257244 -1.38088828537044 5.20257762993834e-16 110.599852095869 13.3305747135955 8.29670546634956 5.14669323175224e-15 12.4548288445562 24.2589992525911 0.513410661127164 0.608083942202958 TEX30 other 7.05677629724836e-12 1 7.53167087534622e-11 8.29670546634956 0.513410661127164 1.93517904155714e-09 165.692027482733 33.7636846216469 4.90740360062784 1.58908025144245e-06 -79.3268939462249 54.8242308014432 -1.44693127083758 0.149063408532617 CSNK1G3 other 2.05961105392926e-05 1 0.0173861270310319 4.90740360062784 -1.44693127083758 1.37460770368302e-08 101.045274375134 19.3081117301489 5.23330690164568 3.33166437454877e-07 -12.3589641698727 31.3414505498217 -0.394332870784851 0.693644291880026 SRFBP1 essential 0.000138800090543965 1 0.00381642154104562 5.23330690164568 -0.394332870784851 0.00149042373355977 27.3212502885503 12.7828764072818 2.13733196019846 0.0334899233568253 -30.775470176721 23.0678859977514 -1.33412616048653 0.183312198008154 AKAP6 other 1 1 1 2.13733196019846 -1.33412616048653 0.308575986259446 5.92386743245619 3.85646892387558 1.53608587269594 0.125710393094575 6.20701810935945 7.18869630499908 0.863441414967417 0.388675612712151 NPAS3 other 1 1 1 1.53608587269594 0.863441414967417 0.00413440693832579 51.8664275555002 44.7116278679215 1.16002100636358 0.247108460203374 -168.777505285677 83.6303412331502 -2.01813723102179 0.0446079010305319 MBIP other 1 1 1 1.16002100636358 -2.01813723102179 1.89633595419264e-07 55.4876012615171 15.5721972904932 3.56324802636504 0.000435931128778859 -54.1397696611141 29.1268342320462 -1.85875915074725 0.0641955491772527 MIPOL1 other 0.0017836935985136 1 1 3.56324802636504 -1.85875915074725 7.54616611418764e-10 646.457496892006 130.929545372869 4.93744551736574 1.40499633963672e-06 -508.714478319284 270.099244104481 -1.88343540170183 0.0607405478845939 EXT2 ts 8.21173796545899e-06 1 0.0154170248348338 4.93744551736574 -1.88343540170183 4.12466409851945e-13 157.691131434802 22.3098521593562 7.06822843595893 1.42041013335336e-11 -79.0749188966153 66.2250292041207 -1.19403373387558 0.233544710134244 TMEM18 other 5.15376779110006e-09 1 1.94567780066743e-07 7.06822843595893 -1.19403373387558 0.0042991053608596 39.5633698889726 15.3098926695685 2.58417029713166 0.010286992055943 -36.2662139369814 38.5323836209732 -0.941187918549677 0.347449873106863 KCTD14 other 1 1 1 2.58417029713166 -0.941187918549677 2.18271591920665e-20 701.239943317173 73.926530402271 9.48563309411896 1.31594777348956e-18 -35.1360459226545 186.0604441003 -0.188842105008164 0.850358437668609 NDUFC2 other 3.20597314213073e-16 1 1.9974771253798e-14 9.48563309411896 -0.188842105008164 0.0369138310988555 22.1621898586464 14.8257694160316 1.49484247574238 0.136127709342149 -35.1116873255125 30.4028817241002 -1.15488023945045 0.249164336325261 ME3 other 1 1 1 1.49484247574238 -1.15488023945045 0.751004157984789 -0.762011383954127 32.9373056966772 -0.0231352069586858 0.981559832866674 160.052832592447 215.907923527025 0.741301337986392 0.459167159911977 ADAMTS12 other 1 1 1 -0.0231352069586858 0.741301337986392 5.68443613345816e-21 73.6594594197444 10.281835007913 7.16403826389506 7.69351837806848e-12 -55.2472073693781 18.7498712165948 -2.94653796451044 0.00349838061501271 NUBPL other 8.41239703390474e-17 1 1.06124392507077e-07 7.16403826389506 -2.94653796451044 0.0391650706483027 165.048822606529 78.5983223079654 2.09990261573054 0.0366688168647478 -256.30177461684 209.836596002126 -1.2214350570872 0.22299072096677 NEK7 other 1 1 1 2.09990261573054 -1.2214350570872 1.97725321019981e-06 104.273532248063 34.9693134073736 2.98185815184109 0.0031246482896518 -140.761901006282 58.0920000710941 -2.42308580930275 0.0160423699080463 FER other 0.0172001256755281 1 1 2.98185815184109 -2.42308580930275 5.76987720971711e-18 121.582154522944 17.5113340259693 6.94305495758565 2.79902009955282e-11 -90.1095019504631 32.9978341932024 -2.73077019003344 0.00673002587656567 VIPAS39 other 8.17170406676246e-14 1 3.80078939318278e-07 6.94305495758565 -2.73077019003344 6.27516408641917e-09 68.5109165650096 94.7346325900975 0.723187652623787 0.470192946109536 -660.569010309995 140.431548366443 -4.70385050933356 4.08612551309345e-06 ANKRD50 other 6.47534182077594e-05 0.063355376080514 1 0.723187652623787 -4.70385050933356 1.33348485461947e-19 153.51157659735 43.0450764905605 3.56629814866316 0.000427903704523358 -414.318341419815 72.9656860934523 -5.67826280546678 3.49952542979613e-08 UPF2 essential 1.93848693316032e-15 0.000554639785368388 1 3.56629814866316 -5.67826280546678 5.02293888732236e-23 403.944402669264 62.4457492600588 6.46872537291553 4.62096649130898e-10 -400.93602665219 105.522419163811 -3.79953406896202 0.000179169224823629 CDC123 essential 7.58463771985677e-19 1 6.04006530078997e-06 6.46872537291553 -3.79953406896202 5.03991828825139e-17 71.7745491114548 16.4900011208226 4.35261032340514 1.91058965696046e-05 -80.8987977466196 23.2015257571585 -3.48678783427247 0.000570455219829667 SCLT1 other 7.0049824288406e-13 1 0.191689460282843 4.35261032340514 -3.48678783427247 0.0382498673840478 104.031372590193 119.220155476332 0.872598866983069 0.38365139871419 -301.700939583735 200.873547408041 -1.50194459886189 0.134271427371545 CCDC3 other 1 1 1 0.872598866983069 -1.50194459886189 3.24569876665464e-11 14.2849562674505 16.8389976493016 0.848325806853652 0.397007988387732 -117.991342633508 23.6925658659696 -4.98009980434338 1.13522210782256e-06 C4orf33 other 3.77247567648268e-07 0.0177594146547761 1 0.848325806853652 -4.98009980434338 0.000127839936918239 78.9511021007015 78.7023151586004 1.00316111338783 0.316671452588347 -382.970980289572 132.476858788058 -2.89085191023637 0.00415079789727249 FRMD4A other 0.93450993887233 1 1 1.00316111338783 -2.89085191023637 0.465956081246789 17.85866392477 26.0291787000285 0.686101706495661 0.493242099719456 126.712874324203 108.399622185901 1.16894202921571 0.243465664522951 PTPRO other 1 1 1 0.686101706495661 1.16894202921571 1.45604615203451e-08 937.680605156885 158.516531306082 5.91534900133731 1.00706916174558e-08 -244.240815720071 658.947047031279 -0.37065317588179 0.711188662863944 EPS8 other 0.000146725770740517 1 0.000125017565739096 5.91534900133731 -0.37065317588179 2.03571495226803e-06 78.4453507893525 24.1220831506901 3.2520139450356 0.00130296361439391 -87.0270139240264 43.9898575123702 -1.97834271001114 0.0489834407931321 ACAD8 other 0.0176801843604478 1 1 3.2520139450356 -1.97834271001114 6.29520692134408e-07 108.133273278867 30.7326426895872 3.51851529238991 0.000515049397594276 -108.224656980326 56.045100435484 -1.93102797817105 0.0546057169120707 THYN1 other 0.00569716226381639 1 1 3.51851529238991 -1.93102797817105 1.39384807801151e-13 261.092671943837 47.5088755084962 5.49566095070266 9.55188652999366e-08 -219.55150429026 86.638813535965 -2.5341010031159 0.0118825928590864 VPS26B other 1.7689325958044e-09 1 0.00113065680855535 5.49566095070266 -2.5341010031159 4.78995846138663e-14 483.993210006305 64.6063831287237 7.49141472665298 1.15019369190427e-12 62.013306705906 117.721900616705 0.526777994417685 0.598811143476149 NCAPD3 essential 6.1685085065737e-10 1 1.61855256324768e-08 7.49141472665298 0.526777994417685 5.14106367574563e-22 117.174341664919 15.3590898116438 7.62898994028207 3.99470617043689e-13 -43.9952555635672 21.6046088785249 -2.03638287603062 0.0426804796762367 VTI1A other 7.69617232259121e-18 1 5.68246952744647e-09 7.62898994028207 -2.03638287603062 1.47177197259699e-07 75.0049768813721 65.4759687036643 1.14553443601323 0.253002164676146 -328.01109897592 94.2683566469011 -3.47954616631904 0.000585410306566597 QDPR other 0.00139391523524661 1 1 1.14553443601323 -3.47954616631904 9.56518771930215e-09 43.0839132947977 26.725289736493 1.61210275808413 0.108103526278978 -153.788936416185 37.7600033679065 -4.0727998596233 6.10332258301744e-05 FAM160B1 other 9.76031754877592e-05 0.918122816163313 1 1.61210275808413 -4.0727998596233 0.0190426996482254 9.50709157438627 4.18826440892595 2.26993586033512 0.0240000103215503 -8.22079615594352 8.64207940975358 -0.951252096418532 0.342327161767414 ANO4 other 1 1 1 2.26993586033512 -0.951252096418532 0.000192403186516292 48.2430622802098 12.4382073741123 3.87861858458947 0.000132031139308569 2.28742164007941 24.406827720244 0.0937205632087174 0.925400643707921 TEX9 other 1 1 1 3.87861858458947 0.0937205632087174 1.13364193602075e-17 168.699993765861 19.6189595065235 8.59882470881123 6.56088231916769e-16 -172.597609727335 74.0474266617657 -2.33090625168822 0.0204920992391019 QTRT2 other 1.59628121011081e-13 1 9.70616930297668e-12 8.59882470881123 -2.33090625168822 3.56385351812185e-20 9.37035828457017 10.2210224511198 0.91677308501984 0.360082729691415 -106.283347897747 14.7198675520768 -7.22040110223352 5.31952036896801e-12 MMAA other 5.22033263334488e-16 8.48782670072536e-08 1 0.91677308501984 -7.22040110223352 8.21791899746009e-13 71.5473283010763 36.3205182398707 1.96988731902331 0.0498770419323063 -237.20841359867 52.2088687320353 -4.54345055465872 8.3653463581051e-06 ZNF827 other 1.01631004241589e-08 0.128893256685683 1 1.96988731902331 -4.54345055465872 0.00285413228572896 -105.199662717089 66.674820115328 -1.57780197284559 0.11579070345641 -323.810656136316 96.0602709103817 -3.37091133584675 0.000859525004599048 EDNRA other 1 1 1 -1.57780197284559 -3.37091133584675 4.73057844400049e-06 1.43757439577142 29.6059988616324 0.0485568618201369 0.961308614858595 -170.799783786285 43.4657642966007 -3.9295244556333 0.000108377218995491 NR3C2 other 0.0398220093415961 1 1 0.0485568618201369 -3.9295244556333 0.0672142372588203 7991.05503333942 3796.29911422464 2.10495927557371 0.0362363508650593 2542.81090642857 6519.82715045594 0.390012012243415 0.696840951869778 AKR1C2 other 1 1 1 2.10495927557371 0.390012012243415 0.00933666936178168 125.990621684302 45.4747467958507 2.77056235738728 0.00598746958612154 39.9089188529107 63.097897213253 0.632492057826109 0.527604642812308 DPYSL4 other 1 1 1 2.77056235738728 0.632492057826109 0.311070797005774 -3.2029853283932 7.91490374298505 -0.404677736129387 0.686043337361527 -15.5918785465828 11.0566739723134 -1.41017801425871 0.1596686810909 VENTX other 1 1 1 -0.404677736129387 -1.41017801425871 0.0106925553382257 133.38812244522 159.426948228319 0.836672368928447 0.403536320676302 -395.208029357382 222.710451851509 -1.77453741426058 0.0771310637014204 ADAM8 other 1 1 1 0.836672368928447 -1.77453741426058 0.701179718486481 -3.86793158314963 8.54017332979486 -0.452910196758565 0.650975796529291 -12.1989189648652 14.4869083453185 -0.842065033759068 0.400494044121894 ITIH2 other 1 1 1 -0.452910196758565 -0.842065033759068 1.51013523735526e-23 42.3528282262962 10.3026315106172 4.11087479763303 5.22894889985969e-05 -108.778319987928 17.4766099757236 -6.2242231267408 1.83230127759378e-09 KIN essential 2.29012008744925e-19 2.91665717367378e-05 0.504122963435473 4.11087479763303 -6.2242231267408 1.34677345065147e-09 155.950099395619 23.5582756199293 6.61975867468381 1.96533442008245e-10 130.196002590204 97.1458783209535 1.34021128678315 0.18131600899009 PIGF other 1.44522258989409e-05 1 2.60328197284121e-06 6.61975867468381 1.34021128678315 3.82989460447313e-08 12.7505676019079 2.36847369266121 5.38345333596736 1.59697483880369e-07 -6.56221541794245 5.97242595179692 -1.09875207677846 0.272862313875021 ANKAR other 0.000376440340673664 1 0.00186622479662599 5.38345333596736 -1.09875207677846 0.862006939038316 37.4491227674819 89.9303392390073 0.41642367953215 0.677433307695711 -49.8681580165776 228.95448933403 -0.217808168608666 0.827744323257414 INPP1 other 1 1 1 0.41642367953215 -0.217808168608666 9.3093013754454e-05 256.856444700712 83.8597544075623 3.06292865410001 0.00241582635184749 -453.205896928424 212.457904604346 -2.13315620227177 0.0338238516772646 MFSD6 other 0.692705115346893 1 1 3.06292865410001 -2.13315620227177 0.02490562033652 95.4195839752299 35.108994080904 2.71781024985644 0.00699513720464858 122.971215214273 104.115292167542 1.18110618194672 0.238596051843098 RNF144A other 1 1 1 2.71781024985644 1.18110618194672 6.68945489355156e-09 317.605616856751 54.3183916296225 5.84711011000453 1.43516824187809e-08 -75.9437020385342 163.47706845121 -0.464552629662548 0.642624860904223 ASAP2 other 6.88946959486875e-05 1 0.000176913189176312 5.84711011000453 -0.464552629662548 1.93332563780222e-09 658.148837169125 114.952349247573 5.72540571355936 2.73376299534891e-08 -419.189594556853 347.057916108013 -1.20783758301134 0.228162754909358 ADAM17 other 2.05783180887669e-05 1 0.000332343567344567 5.72540571355936 -1.20783758301134 0.46755144619697 59.9421786998905 49.0917876536245 1.22102252871341 0.223138733082117 68.395985016568 89.882379544346 0.760949869855448 0.447348615021723 FLI1 other 1 1 1 1.22102252871341 0.760949869855448 0.00387831838312801 3.83636865099996 47.6017220530022 0.0805930644006608 0.935825287297823 -249.471718077138 87.4881684322377 -2.85149092211664 0.00468759391676483 TMEM45B other 1 1 1 0.0805930644006608 -2.85149092211664 0.00124829194614994 74.040249820945 110.878458548308 0.667760454017198 0.504856880516735 -399.657092156884 166.43040882126 -2.40134657474825 0.0170112524485068 WWC2 other 1 1 1 0.667760454017198 -2.40134657474825 2.83216194851175e-08 274.802191278978 60.6104866257797 4.53390504807621 8.71181393626134e-06 -27.3312019809736 93.3994226564058 -0.292627097723276 0.770031950635902 CENPU other 0.000281035430150821 1 0.0898972080082807 4.53390504807621 -0.292627097723276 1.04063666213518e-06 246.691932912728 175.911585229434 1.40236319621006 0.161951280274303 -852.292290651637 271.234557683172 -3.14227028418405 0.00186242507399933 ACSL1 other 0.00925125992638179 1 1 1.40236319621006 -3.14227028418405 2.61712778997047e-09 318.391140348908 69.0515749486592 4.61091786227377 6.18426816502806e-06 -70.3121010051109 106.469243421906 -0.660398240330167 0.50955923766168 SLC25A4 other 2.76159324397684e-05 1 0.064563759642893 4.61091786227377 -0.660398240330167 1.8237118671887e-07 48.1379504883169 8.6018424173603 5.59623719578547 5.46052223335763e-08 -8.44759154231457 57.1882732717533 -0.147715450371659 0.882679665595495 AMN1 other 0.00171665998058472 1 0.000654935036668915 5.59623719578547 -0.147715450371659 7.56510675272042e-08 77.2925230984543 14.1182823532206 5.47464069386759 1.01990151521673e-07 -100.728825922455 91.4682453009216 -1.10124366758176 0.271793647940061 BICD1 other 0.000729957150569993 1 0.00120521762053161 5.47464069386759 -1.10124366758176 1.92002121203096e-12 194.305664473746 33.9549564461604 5.72245365067218 2.79516444212457e-08 -129.923069184626 65.0051015334103 -1.9986595839382 0.0466514271913854 SAV1 other 2.34127386595055e-08 1 0.00033950067314045 5.72245365067218 -1.9986595839382 2.53196626429124e-08 27.8600226504958 6.41803544474323 4.34089572897497 2.00098139952826e-05 -15.8403721817779 10.1500262215157 -1.56062376944407 0.11977100413205 CCDC122 other 0.000251793677229614 1 0.200358267534764 4.34089572897497 -1.56062376944407 0.00915050633310398 3.30275257823924 5.25108269070004 0.628966019538904 0.529897225011587 -19.173311199972 8.30450804780259 -2.30878350524874 0.0217026901159493 SERP2 other 1 1 1 0.628966019538904 -2.30878350524874 2.86461549174279e-09 236.241868248506 36.9900062120054 6.38664040482998 7.4914962530648e-10 37.7989531439919 115.631694298232 0.326890939144266 0.744006491001544 NBAS essential 3.01729949745268e-05 1 9.7232129868528e-06 6.38664040482998 0.326890939144266 0.704137967238039 -0.586785854889882 5.23470348064333 -0.112095337789366 0.910831413854557 -11.0982376508186 13.5551218933311 -0.818748642627756 0.413654564900048 ZNF385D other 1 1 1 -0.112095337789366 -0.818748642627756 0.597577170928158 -29.5145304318321 29.387568674731 -1.00432025386334 0.316113616776085 -31.2303043641731 43.5642077463791 -0.716879887865488 0.474061074609067 TDO2 other 1 1 1 -1.00432025386334 -0.716879887865488 2.17938837408856e-15 151.929144006117 38.2599471856871 3.97097108547376 9.26206793058939e-05 -189.105286659287 58.2162198839512 -3.24832644641393 0.00131298294278132 GUF1 other 2.91100905127009e-11 1 0.871745833627073 3.97097108547376 -3.24832644641393 0.536413957298302 -4.9236122295765 9.6544745846099 -0.509982411412132 0.610493119886563 -17.4390618029245 15.9070730993618 -1.09630864798277 0.273950387210065 GABRA2 other 1 1 1 -0.509982411412132 -1.09630864798277 2.42455189963041e-08 237.824674955798 50.2377430133546 4.73398406637371 3.5578371337759e-06 -40.5038316608028 76.6735955585176 -0.52826310499408 0.597750650211837 SACS other 0.000241315650570215 1 0.0378589449405093 4.73398406637371 -0.52826310499408 0.000102963277378076 4.33603041933933 1.99570813246027 2.17267763197114 0.0306680050796122 -8.07050041631248 3.70007538616287 -2.18117188814413 0.030027207309661 CCDC175 other 0.762237142429898 1 1 2.17267763197114 -2.18117188814413 0.790077510167352 105.218863329493 215.394619475068 0.48849346184189 0.625592508216259 236.155709862361 351.984204666405 0.670927009597431 0.502834264212557 PABPC3 other 1 1 1 0.48849346184189 0.670927009597431 4.18458766727439e-09 101.921699348292 26.6515658664124 3.82422931017116 0.000162589647538677 -95.9871052748636 43.3209043855804 -2.21572256249603 0.0275355363076328 CENPJ other 4.35699267916609e-05 1 1 3.82422931017116 -2.21572256249603 3.10884810328655e-18 66.9459818767742 7.41522173881861 9.02818340904261 4.64184182912169e-17 -101.095452019922 47.5360488735481 -2.12671129417694 0.0344159632978048 FBXO4 other 4.42389085097676e-14 1 6.95069395492681e-13 9.02818340904261 -2.12671129417694 7.61600612693015e-17 95.6822023043197 10.6752505371526 8.96299360575392 7.82367108705372e-17 -70.8365366781489 68.7760144389917 -1.02995989598939 0.304032264085933 TMEM267 other 1.05435988821221e-12 1 1.16956059080366e-12 8.96299360575392 -1.02995989598939 1.89415421077146e-08 63.1983996057757 11.1080572201414 5.68941970259056 3.58132479563723e-08 -106.331967037014 71.5644003953619 -1.48582209100581 0.138596271571511 CCL28 other 0.000189756368835085 1 0.000432784349232881 5.68941970259056 -1.48582209100581 2.9738788876007e-06 65.0910433940522 36.0958392813663 1.80328383242924 0.072524006056069 -170.008429289395 58.6653014300096 -2.89793839195088 0.00408288605193851 PARP8 other 0.025441533883424 1 1 1.80328383242924 -2.89793839195088 0.712431272388194 21.6970671640372 41.2624899613784 0.52583029246043 0.599436137630347 -12.6873988923358 57.5640986408839 -0.220404717382732 0.825721921094218 GFRA1 other 1 1 1 0.52583029246043 -0.220404717382732 1.04359726412188e-17 299.529946929492 63.1719816535591 4.74149993540082 3.43813673617993e-06 -371.168036865049 87.9879001321387 -4.21839862421577 3.36201778082368e-05 CACUL1 other 1.47074162432697e-13 0.510152578062186 0.0366127181035801 4.74149993540082 -4.21839862421577 1.38663884768137e-09 4438.60347711007 778.304228837986 5.70291579134414 3.21689992887653e-08 -2557.8495128903 1889.0045414659 -1.35407271753056 0.176898016517458 DST other 1.4870315002535e-05 1 0.000389630919385525 5.70291579134414 -1.35407271753056 0.000115729976116673 33.2734266782443 8.36467066639658 3.97785256649897 9.07522354715255e-05 -4.62501809009884 17.7881300831838 -0.260005861688135 0.7950698885767 BEND6 other 0.85049959448143 1 0.854795305906299 3.97785256649897 -0.260005861688135 1.51726800366692e-15 392.66034030832 72.617746349834 5.40722289034818 1.40946890363697e-07 -282.804140565998 100.826327535452 -2.80486404175099 0.00539955497175954 TIAL1 other 2.03480811971771e-11 1 0.00165232039573362 5.40722289034818 -2.80486404175099 0.000228283665268085 474.930389325751 180.56142277437 2.6302982222245 0.0090208060117719 -308.208044189733 250.701048545518 -1.22938474321448 0.219997853984183 BAG3 other 1 1 1 2.6302982222245 -1.22938474321448 0.249530196473553 4.7348875203474 13.3996747948036 0.353358390621807 0.724094495498999 -41.4608990507333 27.8564168359656 -1.48837875649545 0.137813748042016 GLT1D1 other 1 1 1 0.353358390621807 -1.48837875649545 0.769613749814808 3.43535026418955 6.24909474921421 0.549735666053316 0.582953442737626 -4.21002215783193 13.0342632057033 -0.322996558485161 0.746946925507815 TMEM132D other 1 1 1 0.549735666053316 -0.322996558485161 8.91117247643589e-08 153.921007217893 26.3440330710976 5.84272752780444 1.54868581806102e-08 -67.2070805394734 171.35175186484 -0.392217061150827 0.695222905208664 SCHIP1 other 0.000855704874371106 1 0.000190581276770589 5.84272752780444 -0.392217061150827 0.203927360867784 39.2136053218322 55.806147780403 0.702675366092955 0.482859012099332 -82.9221550859063 82.1732428951389 -1.00911382056229 0.31381688856524 KCNE4 other 1 1 1 0.702675366092955 -1.00911382056229 0.00323964248693056 32.3814362947059 16.845450081147 1.92226602071894 0.0556166910996182 -33.3095466063174 24.7076298298848 -1.34814819696012 0.178732329320145 AP1S3 other 1 1 1 1.92226602071894 -1.34814819696012 8.01138125662715e-08 275.486639070334 48.191480520474 5.71650084402978 2.90342510225505e-08 -133.120875706037 155.970667024132 -0.853499431950494 0.394147447822993 RABGAP1L other 0.000771816470263459 1 0.000352330636158651 5.71650084402978 -0.853499431950494 0.0215759072371179 21.612692429401 7.82049166219211 2.76359765638352 0.0061057027730339 12.8745780763799 21.3133672102747 0.604061195462973 0.546304592457038 CCDC74B other 1 1 1 2.76359765638352 0.604061195462973 0.0368357837851303 53.2643501531259 22.8097384895102 2.33515829993497 0.0202626255539785 11.4939616318039 36.9370663089339 0.311176895741281 0.755904496493903 TMEM56 other 1 1 1 2.33515829993497 0.311176895741281 4.64620668763269e-06 427.635895514985 110.911354812533 3.85565478158474 0.000144001687384213 -525.083940973636 300.714045966051 -1.74612376115253 0.0819142820473327 MZT2B other 0.039162876170056 1 1 3.85565478158474 -1.74612376115253 0.422746361719969 8.52231921436363 9.67526339402838 0.880835887075038 0.379181441531269 -15.9644876500347 26.2325494618945 -0.608575528399359 0.543311851669198 TUBA3E other 1 1 1 0.880835887075038 -0.608575528399359 0.952237098201021 1.6710409990054 6.25647890296293 0.267089688133374 0.789604754485513 -2.69880974823347 20.115453502708 -0.134165990732953 0.893371642032469 ASTN1 other 1 1 1 0.267089688133374 -0.134165990732953 4.77649472787743e-06 475.555134880409 137.014836087181 3.47082949891513 0.000603569389836902 -758.506419368011 349.528389862816 -2.17008529597756 0.0308691101036366 FAM168B other 0.0401846501456328 1 1 3.47082949891513 -2.17008529597756 0.0128667718683182 209.10748122864 91.6913725404445 2.28055786967748 0.0233483688322398 -385.626362711507 249.452599164745 -1.54589033749385 0.12329371153188 PTPN14 other 1 1 1 2.28055786967748 -1.54589033749385 8.23522418266883e-06 615.896284943089 139.11736817877 4.42717033110952 1.38563120421906e-05 -130.670701013917 343.586136032601 -0.380314242369543 0.704010076430263 MGAT5 other 0.0679158938344698 1 0.140586141980066 4.42717033110952 -0.380314242369543 0.728940044047942 -11.5567058007058 33.0458191947128 -0.34971763697584 0.726823239820066 -64.6482067466975 81.4748777034051 -0.79347411826794 0.428198393519714 TMEM163 other 1 1 1 -0.34971763697584 -0.79347411826794 8.33826358473722e-07 53.1312130016626 9.80525943345349 5.41864428598289 1.3233843870009e-07 25.348777986669 36.2474890889567 0.69932507392331 0.484946487469993 GPATCH11 other 0.00746691504013218 1 0.00155418262409386 5.41864428598289 0.69932507392331 0.603360352201335 33.3705168031666 103.0208191641 0.323920126765942 0.746249280477137 -168.954109008752 212.558034251396 -0.794861081604317 0.427392457197829 HSPB8 other 1 1 1 0.323920126765942 -0.794861081604317 1.94161053077134e-10 84.935560915256 12.1929825554801 6.96593803269916 2.45479612437278e-11 6.89941739361952 44.896077116992 0.153675283825817 0.877979725465491 GEMIN6 essential 2.17868117657852e-06 1 3.33975012720916e-07 6.96593803269916 0.153675283825817 0.570712698868672 -15.1509799282496 20.7181150462055 -0.731291427548304 0.465228380096798 -66.1136658828527 78.9749208188126 -0.837147605814425 0.403241836054135 TMEM178A other 1 1 1 -0.731291427548304 -0.837147605814425 0.450753257456182 13.6550979411321 12.5808089116778 1.08539109345005 0.278793984235634 -2.89613872942523 25.4670125646043 -0.113721180373173 0.909550093070658 POU4F1 other 1 1 1 1.08539109345005 -0.113721180373173 1.44367031571437e-22 128.388739350341 15.2226362416974 8.4340673528454 2.6963838306226e-15 -88.8337295443173 30.8147966601622 -2.88282705623571 0.00428420023979856 RNF219 other 2.17128015483441e-18 1 3.96017893203542e-11 8.4340673528454 -2.88282705623571 0.357113358804465 -38.7967940433917 50.0168544086273 -0.775674410198411 0.438612669237376 -115.503642560353 80.4584286879834 -1.43556920566116 0.15226971325946 CYSLTR2 other 1 1 1 -0.775674410198411 -1.43556920566116 0.00603979685635859 15.1278378644058 10.4299353231829 1.45042489676621 0.148088017392463 -30.1272240777015 16.7778685273707 -1.79565264971252 0.0736555603052995 ARL11 other 1 1 1 1.45042489676621 -1.79565264971252 3.08309006891662e-12 220.781085866427 36.2217951828413 6.09525521172991 3.77427066177219e-09 -94.2345256106184 60.3832519639499 -1.56060699855779 0.119792179330738 SETBP1 other 3.72745589332019e-08 1 4.77369753300946e-05 6.09525521172991 -1.56060699855779 1.5648081009998e-10 94.9921780303889 19.4019288114643 4.89601724413398 1.7053598203501e-06 -78.6005983375476 37.0635045782165 -2.12070065235396 0.0348794421977339 ARL14EP other 1.76306928739648e-06 1 0.0185969488409178 4.89601724413398 -2.12070065235396 9.25664855453692e-23 399.778783675849 43.0394565933486 9.28865778797104 5.29104061633569e-18 -104.385847894334 73.5632990948055 -1.41899356307832 0.157049989983459 EPG5 other 1.39442153825544e-18 1 7.99529147534485e-14 9.28865778797104 -1.41899356307832 0.0861621953232801 57.6984554442624 39.2628527105512 1.46954312947202 0.142845467115906 -57.9688891595838 67.1083049340343 -0.863810957772898 0.388455632221956 PSTPIP2 other 1 1 1 1.46954312947202 -0.863810957772898 3.48936926175343e-25 3415.1394685516 351.308612103103 9.72119484377831 2.34513243860985e-19 -1224.40136305274 605.006531792214 -2.02378205641133 0.0439737688229568 ATP5A1 essential 5.35129669982507e-21 1 3.5770305086116e-15 9.72119484377831 -2.02378205641133 2.39337020139978e-15 215.78471497181 29.5390899004388 7.30505630671461 3.10208768718979e-12 -66.0171747755272 50.8707777642466 -1.29774258772835 0.19547931429538 HAUS1 essential 3.1927558486673e-11 1 4.32275919209897e-08 7.30505630671461 -1.29774258772835 3.07662839447007e-28 390.661351590302 35.2420299578905 11.0850978804879 8.51477090860976e-24 -60.4375160126112 60.6921025661707 -0.995805277082272 0.320233075051784 C18orf25 other 4.78600313043764e-24 1 1.32574983047054e-19 11.0850978804879 -0.995805277082272 5.46799705004666e-08 80.3389184252475 14.0333827905887 5.72484336984846 2.72375272475931e-08 19.4177382519181 35.645946275248 0.544739031529132 0.586377714088627 SPC25 essential 0.000532309512822042 1 0.000331153856276237 5.72484336984846 0.544739031529132 0.000173885238021561 252.937883593524 71.6522578441867 3.53007555105321 0.000488263505616623 -224.239959632575 214.79614823568 -1.04396639080573 0.297434723531373 PDK1 other 1 1 1 3.53007555105321 -1.04396639080573 0.0160724049765226 31.3846153846155 32.4862161237896 0.966090210845844 0.334883196194663 -88.8271391529816 53.5899233907588 -1.65753435595131 0.0985992770679848 PDE3B other 1 1 1 0.966090210845844 -1.65753435595131 0.0424992420301097 154.774682971015 68.5570654261844 2.25760367671602 0.0247814433135793 395.097599637682 282.143834345244 1.40034107268218 0.162576551821723 TCF7L1 other 1 1 1 2.25760367671602 1.40034107268218 0.0287711872995161 514.478234242586 203.799057889564 2.52443872690213 0.0121683935845906 -502.114591057557 839.405852676773 -0.598178568157905 0.550227855945684 TGOLN2 other 1 1 1 2.52443872690213 -0.598178568157905 0.378566374473815 4.72525568810086 4.06737573735682 1.16174555615842 0.246364784188159 10.5513805005884 8.85534511797139 1.19152674006742 0.234493182514246 KCNK13 other 1 1 1 1.16174555615842 1.19152674006742 8.51947516369395e-08 505.346095746366 92.8072425906782 5.44511486000258 1.15443468899382e-07 -604.849162162773 320.654816809198 -1.88629370418184 0.0603167056344538 UHMK1 other 0.00081923273174081 1 0.00136073216791701 5.44511486000258 -1.88629370418184 9.03024050386938e-12 897.912183418981 194.837489033885 4.60851855498314 6.23194801021592e-06 -870.553986449504 305.788353415504 -2.84691675378035 0.00474966044509123 ATG10 other 1.07252166464457e-07 1 0.0650490733306338 4.60851855498314 -2.84691675378035 4.31970465082671e-17 75.6505935368114 10.8054072768108 7.00117927985583 1.98429045651873e-11 -33.9368576972023 17.0415229213734 -1.99142165015304 0.0474346014722051 POC5 other 6.01562069674128e-13 1 2.70736589887416e-07 7.00117927985583 -1.99142165015304 0.128761533471654 236.437522950464 118.837133490134 1.9895929496658 0.0476334097544006 257.23147250181 197.367618150536 1.30331142926199 0.193566553316777 SPOCK1 other 1 1 1 1.9895929496658 1.30331142926199 0.00368002903105443 4.3282637595318 1.84542312111424 2.34540453623365 0.0197225712360402 -2.78837720837248 2.89630553318352 -0.962735863473488 0.336532059391561 FAM151B other 1 1 1 2.34540453623365 -0.962735863473488 1.73461941858988e-17 160.672987397718 17.1422988200536 9.3728961957983 2.95347382036686e-18 -39.4051868394702 57.4099175882308 -0.686382919447848 0.493060688947022 TADA1 other 2.43401796816532e-13 1 4.47067332188931e-14 9.3728961957983 -0.686382919447848 0.9504314317227 0.350873625824849 27.7401811782239 0.0126485700857746 0.989917476789492 -17.9406196078153 60.9151585939626 -0.294518146581555 0.768587473983135 GUCY1A2 other 1 1 1 0.0126485700857746 -0.294518146581555 7.12670494829616e-20 124.140567768705 14.9064132146074 8.32799721713433 4.17181311316774e-15 -26.6139942913443 26.6140980110131 -0.999996102829834 0.318207747934782 CWF19L2 essential 1.03985751900589e-15 1 6.11254057341337e-11 8.32799721713433 -0.999996102829834 4.31590665505806e-05 77.2855711980419 43.2462975041147 1.78710261128571 0.0750343355320762 -187.61439693243 67.8382816219842 -2.76561246020168 0.00607059658661963 JMY other 0.332713244038426 1 1 1.78710261128571 -2.76561246020168 7.17607371847815e-05 84.9889266039737 27.6172324917665 3.07738751988677 0.00230140400993673 -54.7040615941834 43.3217570872515 -1.26273875466333 0.20776454120275 HOMER1 other 0.540430111738589 1 1 3.07738751988677 -1.26273875466333 1.15944100868635e-10 71.8508324084348 11.3860276986348 6.310438926567 1.12471890303284e-09 6.37564322469971 17.8534863505861 0.357109143811029 0.721287000791438 XRCC4 other 1.31457421564858e-06 1 1.45099985680267e-05 6.310438926567 0.357109143811029 2.08248347578392e-08 9.45601734945488 3.11566482940527 3.03499184514654 0.00263839220818481 -25.0456106473367 6.94357672493014 -3.60701863600257 0.000368453591664909 ZNF547 other 0.00020808174890033 1 1 3.03499184514654 -3.60701863600257 9.14149606662363e-09 25.9601353051355 8.0851193949825 3.21085367289022 0.00148231159390709 -64.8241636491776 17.9331706921672 -3.61476309805558 0.00035810546483198 ZNF773 other 9.33712408244937e-05 1 1 3.21085367289022 -3.61476309805558 8.16337480114353e-08 46.7673489371661 14.3722838356617 3.25399563993603 0.00128233555097032 -114.005705079672 34.4952867216303 -3.30496470429929 0.00107789882888787 ZNF776 other 0.000786214627098134 1 1 3.25399563993603 -3.30496470429929 7.23756730747831e-07 28.4191879639759 6.80521526040454 4.17608949555646 4.01033866997691e-05 -27.1731672069205 16.515769386195 -1.64528618507071 0.101078756990264 ZNF256 other 0.00651627491505201 1 0.391008020322748 4.17608949555646 -1.64528618507071 4.00481479134876e-12 112.482959784212 19.4805287868206 5.77412251048912 2.10747987925625e-08 -27.1391775110768 32.8226624697699 -0.826842658972969 0.409050997710229 SUV39H2 other 4.82019508286736e-08 1 0.000257470816848736 5.77412251048912 -0.826842658972969 7.87706978306188e-19 39.1645044659814 10.7097146556725 3.65691390715415 0.000306411730611073 -99.3400054214096 18.0447539765196 -5.50520143143396 8.52813641628478e-08 DCLRE1C other 1.13185615712816e-14 0.00134855421150711 1 3.65691390715415 -5.50520143143396 2.27794264076471e-24 79.3063659566018 13.6034906812588 5.82985410251063 1.56784309790232e-08 -113.554105286065 22.9204652464924 -4.95426703013555 1.27744124551005e-06 RPP38 other 3.47568488127879e-20 0.0199600194610946 0.000192876057903944 5.82985410251063 -4.95426703013555 5.00198863784847e-11 60.8581890964762 22.0492979218424 2.76009645804591 0.00617115705590991 -145.894852333401 37.1507709725854 -3.92710160553764 0.000109040387398613 NMT2 other 5.77129449034956e-07 1 1 2.76009645804591 -3.92710160553764 0.00225625783515758 2.59291471847782 2.57115695935419 1.00846224461112 0.314152520987258 -17.1310529195052 6.24318793229652 -2.74395919284839 0.0064848971287674 ZNF837 other 1 1 1 1.00846224461112 -2.74395919284839 2.62852204554837e-05 113.820237542872 42.5629505698369 2.67416229417924 0.00794504914483657 -120.205780397511 66.9003780811633 -1.79678775883266 0.0734786866074735 USP12 other 0.207232678071033 1 1 2.67416229417924 -1.79678775883266 8.63928380054516e-05 117.848908381309 31.5431226756179 3.73612053547264 0.000228533441267441 -465.274833220832 239.23215405741 -1.94486746588913 0.0528407520961672 CCDC50 other 0.645354499900724 1 1 3.73612053547264 -1.94486746588913 0.043145619343652 39.7543518619636 15.7985625559484 2.51632714819333 0.012432266854966 27.201841942412 26.0479206865515 1.04429993740177 0.297270455111182 CAMK4 other 1 1 1 2.51632714819333 1.04429993740177 0.00939911677243127 28.027055393586 14.7518563537894 1.89990023773425 0.0584998755364895 -30.064974209464 24.1292854773586 -1.24599521347929 0.213834350470742 TRIM36 other 1 1 1 1.89990023773425 -1.24599521347929 0.54643709967763 34.169378772014 180.780278540431 0.189010543892774 0.850225507232325 797.187000224668 725.160126484187 1.09932547462267 0.272598179615349 ZFP36L2 other 1 1 1 0.189010543892774 1.09932547462267 1.07863584620476e-16 124.213591209785 33.3302837308767 3.72674868935231 0.000236083547304563 -267.700098451637 52.5181674387827 -5.0972855967162 6.47396000946717e-07 PAN3 other 1.48679165040863e-12 0.0101608802348587 1 3.72674868935231 -5.0972855967162 0.923966710788622 -3.61539472264829 32.4551644993679 -0.111396592142329 0.911384018888286 47.5318716649538 130.186718282786 0.365105383190526 0.715316473094949 PLEKHH2 other 1 1 1 -0.111396592142329 0.365105383190526 2.21511733854492e-05 287.566234330374 76.3165733973444 3.76807057142296 0.000201879031630578 -286.297431612865 194.306413040358 -1.47343274538962 0.141794950529518 PFKM other 0.176101828414321 1 1 3.76807057142296 -1.47343274538962 3.07012222262752e-22 4432.61760603172 424.150079044503 10.4505877165394 1.0604151301914e-21 590.341824330411 927.695895508439 0.636352739285178 0.525083631848896 TMEM123 other 4.60671839505259e-18 1 1.63611450437231e-17 10.4505877165394 0.636352739285178 0.106900597344541 61.6174812289636 29.5136542765785 2.08776184241821 0.0377672050468049 -51.3262183037589 193.903207414004 -0.264700202685002 0.791444643934402 IGSF10 other 1 1 1 2.08776184241821 -0.264700202685002 6.31067860863767e-06 43.120048954193 8.9271540771088 4.83021224700965 2.28419024547039e-06 -22.9111961192427 57.8070550366743 -0.396339099175823 0.692166778512649 SPEF2 other 0.0524985353452568 1 0.0246761072218167 4.83021224700965 -0.396339099175823 0.166897534537685 178.37262619984 896.643367383613 0.198933748565305 0.842463188953461 -1884.77107620645 1389.03713654724 -1.35689034268117 0.175941038324854 SPARCL1 other 1 1 1 0.198933748565305 -1.35689034268117 8.14440633401128e-10 368.705153503741 57.405690708316 6.42279796574817 6.0382413557482e-10 -573.97115948283 370.712727753631 -1.54829094474544 0.122727916766438 MBNL1 other 8.84808304126985e-06 1 7.86118642104859e-06 6.42279796574817 -1.54829094474544 0.240067535729481 3.26569259734016 3.95508656433338 0.82569434175977 0.409703785648696 -34.0156725684987 25.9944077728305 -1.30857655484085 0.191786497973982 CAPSL other 1 1 1 0.82569434175977 -1.30857655484085 2.46162945330956e-23 186.082181712182 16.7786193777711 11.090434649153 8.99253214010232e-24 -14.2398515847475 112.54536907699 -0.126525433267773 0.899410890081427 NADK2 other 3.72739931820133e-19 1 1.40004732889253e-19 11.090434649153 -0.126525433267773 0.00100146409816946 87.0449176202169 69.3327851943872 1.25546546812118 0.210391268284756 -700.898511488453 228.004771191599 -3.07405194998953 0.00232721952719962 GPD1L other 1 1 1 1.25546546812118 -3.07405194998953 0.00668034615068787 1666.37217061363 934.543609333151 1.78308658255411 0.075699720808066 -3151.95651538124 1715.58227131026 -1.83725174134259 0.0672757533439731 GJA1 other 1 1 1 1.78308658255411 -1.83725174134259 0.000286592106987987 89.2411940135659 28.9171542958944 3.08609875994043 0.00223806315142886 -28.4072075430524 52.4105252777705 -0.54201341033117 0.588254645773155 CCNO other 1 1 1 3.08609875994043 -0.54201341033117 4.72586565154259e-10 210.085380339772 32.1384738809862 6.53688103292495 3.12300914166677e-10 277.44055650186 126.350978116 2.19579270883956 0.028957591111937 SLC30A6 other 5.198924803262e-06 1 4.10613241946347e-06 6.53688103292495 2.19579270883956 2.0601307185015e-15 170.16413459627 27.9470440669052 6.08880617888951 3.96058294950971e-09 -98.7550119136246 51.1187314160466 -1.93187524764405 0.0544369217949499 PELO essential 2.75357071834911e-11 1 5.00538473159037e-05 6.08880617888951 -1.93187524764405 0.504322050965064 -8.37178094961734 14.0261587610781 -0.596869113791055 0.551091247081681 -54.504138617589 52.789989808834 -1.03247109565587 0.302768615180898 RASGRP3 other 1 1 1 -0.596869113791055 -1.03247109565587 2.54229351919932e-11 158.881023228462 57.0502957854348 2.78492900064902 0.00572863491448777 -418.543865249716 92.7986545527211 -4.51023635274724 9.62558608632023e-06 SAR1B other 2.96634807820177e-07 0.148137769868468 1 2.78492900064902 -4.51023635274724 2.75975485963841e-10 98.2972017952885 23.3187109631803 4.21537888395707 3.45203663038648e-05 -105.42468016249 40.670889413879 -2.59214100507262 0.0100818619032553 GPR180 other 3.07298703620737e-06 1 0.338575752708306 4.21537888395707 -2.59214100507262 0.325599247329799 -6.10397830018084 4.17328558898858 -1.46263134166674 0.144722768861687 -3.42289705057057 6.45543919360931 -0.530234573963477 0.596381889230285 TCTEX1D1 other 1 1 1 -1.46263134166674 -0.530234573963477 0.577105069616086 5.29961962960648 16.9898936595129 0.31192776928531 0.755334389188626 -17.3667768285839 26.2807859865288 -0.660816492987917 0.509289294543831 WDR78 other 1 1 1 0.31192776928531 -0.660816492987917 0.333369480776285 44.9796778109643 44.1676380102337 1.01838540246464 0.30941328760419 -14.0484770328015 63.5145213318288 -0.221185277606138 0.825116598767053 ANKRD22 other 1 1 1 1.01838540246464 -0.221185277606138 3.35752438764071e-19 1450.97629815475 188.450398971383 7.69951300753195 2.6674924339536e-13 -753.433815150533 338.780982686708 -2.22395545693095 0.026988120521773 FARP1 other 4.85262999745712e-15 1 3.80571145552159e-09 7.69951300753195 -2.22395545693095 0.000561882207440366 76.2491457723801 44.2074196762036 1.72480425980221 0.085707127622693 -109.133551894136 63.3326911112681 -1.72317881933047 0.0860010716947559 IFIT5 other 1 1 1 1.72480425980221 -1.72317881933047 0.125003644743239 -2.88447136990965 11.1062549584511 -0.259715933111617 0.795280827914885 -28.0442776444431 15.9111076791754 -1.76255972933598 0.0791061574162021 SLC16A12 other 1 1 1 -0.259715933111617 -1.76255972933598 1.53736245128098e-09 60.7809040809025 15.9959104094157 3.79977772600707 0.000179002149538438 -44.579122313823 22.9161543565132 -1.94531428006169 0.0527750227228444 PANK1 other 1.64467035038039e-05 1 1 3.79977772600707 -1.94531428006169 0.0311808662232759 25.5417878879256 11.2281963270399 2.27478992564599 0.0237058765395252 5.29378511877206 17.4918046496423 0.302643736584396 0.762395270658611 PRDM8 other 1 1 1 2.27478992564599 0.302643736584396 0.0908124974298955 -102.301544759028 155.592832353314 -0.657495227843954 0.511424735336539 -488.335851079382 236.192838263157 -2.06753030561959 0.0396404654245732 BMP3 other 1 1 1 -0.657495227843954 -2.06753030561959 0.00010758153523627 465.315355915515 183.617940823076 2.53414973411486 0.0118377236125404 -354.038239275078 278.30673318952 -1.27211524930655 0.204426699149611 HNRNPDL other 0.794274474649385 1 1 2.53414973411486 -1.27211524930655 0.0405941282700709 -2.90273567618762 25.1565302532952 -0.115386965013086 0.908223547399671 -98.5248268063568 42.8110980044645 -2.30138518745962 0.0221259927755898 HHEX other 1 1 1 -0.115386965013086 -2.30138518745962 0.0522311064634199 228.180116666004 184.109604243304 1.23937106705449 0.216280349088888 -508.855142947754 324.121704852511 -1.56995084046995 0.117593370474973 UTRN other 1 1 1 1.23937106705449 -1.56995084046995 0.0721932969317581 7.46607153504444 16.7425004109909 0.445935275602157 0.656001384946085 67.1232177727097 29.4410658742605 2.27991805933201 0.0233925990802186 GRM1 other 1 1 1 0.445935275602157 2.27991805933201 8.19416940637836e-08 608.538055220069 143.937613142911 4.22779037342984 3.22952178278374e-05 -650.320660065948 269.232299158453 -2.41546301130538 0.0163771585155437 PTPRK other 0.000789098513834236 1 0.317461991247641 4.22779037342984 -2.41546301130538 2.71352760070163e-09 141.34830305108 22.9275006375036 6.16501141078893 2.52480753609162e-09 -77.8046508970403 62.0983020298797 -1.25292718727805 0.211304312610434 GGPS1 essential 2.86195756046001e-05 1 3.21281758967659e-05 6.16501141078893 -1.25292718727805 0.305001910271825 113.360879969875 93.9021329224271 1.20722369601043 0.228469006585152 -156.469573377388 282.671299735549 -0.553538946202785 0.580381340388393 ZNF117 other 1 1 1 1.20722369601043 -0.553538946202785 0.117735182602558 40.3487898343233 29.7332265543681 1.35702695301313 0.175914456394588 -32.4348232219941 53.636308582433 -0.604717663821801 0.545878246878757 PART1 other 1 1 1 1.35702695301313 -0.604717663821801 9.9430052010702e-12 104.376780631032 30.8610838672924 3.38214889275662 0.000825272315169704 -195.579776049779 47.6867431697472 -4.10134479835596 5.43586358037248e-05 MARVELD2 other 1.17933984689894e-07 0.819565152012758 1 3.38214889275662 -4.10134479835596 2.95917618320599e-11 99.0340430991789 19.8041318453741 5.00067581211906 1.02764330944444e-06 -64.962921299142 30.6014705468938 -2.12286926537052 0.0346713863133938 RAD17 essential 3.44359332439681e-07 1 0.0113893707985727 5.00067581211906 -2.12286926537052 1.29214096957689e-16 194.240387709138 21.2518625338242 9.13992302556952 1.52028753447263e-17 136.346324002574 133.332709897147 1.02260221147347 0.307407935831442 MED21 essential 1.77824440233171e-12 1 2.28788071062787e-13 9.13992302556952 1.02260221147347 0.00089823252095176 462.64995392552 126.885636548559 3.64619642151902 0.000319679291320691 -355.296196239444 722.868577119178 -0.491508702253171 0.623468992457993 PLOD2 other 1 1 1 3.64619642151902 -0.491508702253171 0.669055190893169 -19.7881467451133 33.3746143445169 -0.592910124469026 0.553735750091815 -46.3517770747185 51.6710166861866 -0.897055642551541 0.37048543489618 STK32B other 1 1 1 -0.592910124469026 -0.897055642551541 0.0776759028977141 -12.5953525452032 7.06273287383076 -1.78335394672398 0.0756477835725984 -24.1400439649601 10.8355622017703 -2.22785338826407 0.0267113155300823 JAKMIP1 other 1 1 1 -1.78335394672398 -2.22785338826407 0.0138824055088093 31.9309930627694 11.1701519180364 2.85859971261543 0.00459068719175289 -23.809189741018 65.3534334652005 -0.364314290444985 0.715911680882545 ZIC1 other 1 1 1 2.85859971261543 -0.364314290444985 5.0300085404877e-09 228.229146118077 79.3768111775955 2.87526221741818 0.004360970286942 -274.685947113805 113.913988042211 -2.41134518977617 0.016566719633834 ADGRA3 other 5.21813085990194e-05 1 1 2.87526221741818 -2.41134518977617 0.774034894082652 7.57906476075952 11.2961314482859 0.670943392917897 0.502838760329756 -12.0000911577028 69.4083609623279 -0.172891147281464 0.862868471115465 CPB1 other 1 1 1 0.670943392917897 -0.172891147281464 3.92438889302046e-12 74.6834342070884 31.8026121561115 2.3483427663264 0.0195787769787609 -252.186569276321 50.2764751377276 -5.01599542500703 9.57453952253719e-07 SREK1IP1 other 4.72614154386454e-08 0.01499660125415 1 2.3483427663264 -5.01599542500703 0.0125242969322521 33.9151700816186 62.3895989719368 0.543602950499391 0.587168313820713 -166.566711064739 89.872576111215 -1.85336526749403 0.0649331054966291 LGI2 other 1 1 1 0.543602950499391 -1.85336526749403 1.5995603806106e-18 162.573099494243 21.337153928124 7.61924950449735 4.32966237412782e-13 -43.9859085637986 33.9989128310397 -1.29374456125671 0.196859297420434 CWC27 other 2.28785121238734e-14 1 6.15201726739822e-09 7.61924950449735 -1.29374456125671 0.329809378685684 57.2347747339823 47.2221621104766 1.21203206664026 0.226563607505249 -117.876813070712 147.9220173829 -0.796884839432553 0.42622068880818 MR1 other 1 1 1 1.21203206664026 -0.796884839432553 6.17541824134652e-15 165.263448727749 28.2422565255594 5.85163754808985 1.39090535653887e-08 -129.646419860944 46.5644931544754 -2.7842334594054 0.00574058896825471 SRP19 essential 8.15031699492914e-11 1 0.000171540357621939 5.85163754808985 -2.7842334594054 1.0008379436198e-08 209.885794935758 34.9396793898372 6.0070898932406 6.06134493129083e-09 74.6675300029248 53.989014924467 1.38301337980306 0.16779917446898 CENPH essential 0.00010200540321373 1 7.59607746789367e-05 6.0070898932406 1.38301337980306 1.3974199486459e-10 215.438302396832 39.4783931115286 5.45711933584043 1.09851622453989e-07 -138.958049670602 71.0666914535407 -1.9553189662902 0.051580737416844 CDYL other 1.57754738002635e-06 1 0.00129635899657953 5.45711933584043 -1.9553189662902 1.20502087961426e-14 441.5838798702 82.433604167812 5.35684305360782 1.82450512612578e-07 -487.95667435534 158.045324826089 -3.08744769826176 0.00223068720678681 CARHSP1 other 1.5772518293271e-10 1 0.00212354151629779 5.35684305360782 -3.08744769826176 0.00435609665536017 28.4103404010443 44.3467935827906 0.64064023812692 0.522299788597768 -139.22446992165 64.9647349172412 -2.14307762663865 0.0330006996243858 BANK1 other 1 1 1 0.64064023812692 -2.14307762663865 5.45863589884543e-09 6.36852461228209 58.2755268016595 0.109283003720538 0.913059808459904 -623.489954950566 113.703212442821 -5.48348583611131 9.63686267005635e-08 TXNDC11 other 5.65077988248479e-05 0.00152291340774901 1 0.109283003720538 -5.48348583611131 0.0420710350090623 122.855271612939 53.5196301515322 2.29551794855633 0.0224968009815616 -230.616647065278 353.089222896307 -0.65313986412155 0.514241039834066 DAB2 other 1 1 1 2.29551794855633 -0.65313986412155 0.151770676274651 -1.70673690674337 8.80066899588727 -0.193932632569293 0.846373383220872 52.0462948898189 28.5136988555367 1.82530842994131 0.0690510619505189 ACOXL other 1 1 1 -0.193932632569293 1.82530842994131 0.231322177320867 108.284186742888 65.2131144468281 1.66046642092485 0.0979814856951317 1.39037974683474 211.075868749218 0.00658710896263881 0.994749149745589 BCL2L11 other 1 1 1 1.66046642092485 0.00658710896263881 3.88409038241228e-12 263.833154447681 36.6122495872309 7.20614432115359 5.80744467289986e-12 -64.01218539855 118.438680511936 -0.540466890730843 0.589322291257341 ANAPC1 essential 4.67877527465383e-08 1 8.03343821602237e-08 7.20614432115359 -0.540466890730843 1.56060545874297e-13 1094.94672694372 297.811620059508 3.67664205555489 0.000284521708790318 -2329.76252697232 525.688373006656 -4.43183194950143 1.35444058966312e-05 CAST other 1.97697499513559e-09 0.207838908483806 1 3.67664205555489 -4.43183194950143 7.56554358258425e-11 482.905563821843 104.110835631828 4.63837948174352 5.47838623513066e-06 -220.914184798371 154.570922131369 -1.42920920540681 0.154100057477381 SCOC other 8.65573841283464e-07 1 0.0574627932202855 4.63837948174352 -1.42920920540681 0.0279062067050007 65.9616061114567 52.3629590223621 1.25969974468569 0.208865487417809 -85.9506890601309 77.7420603003902 -1.10558800124441 0.269889049309856 CLGN other 1 1 1 1.25969974468569 -1.10558800124441 2.61552945575518e-18 125.49466568417 18.4868626475347 6.78831600995885 7.14014568411807e-11 -78.0664066254441 29.7202510007295 -2.62670751412994 0.0091122562696461 CETN3 other 3.72660636855998e-14 1 9.58421755179168e-07 6.78831600995885 -2.62670751412994 6.17908019748379e-21 569.706719400798 129.58219687004 4.39648912552522 1.58555804764365e-05 -843.997274602928 189.381843011813 -4.45659024740973 1.22314183731323e-05 SMARCA5 other 9.13947752009828e-17 0.187886817629685 0.160173073972961 4.39648912552522 -4.45659024740973 2.52923114047313e-08 54.5469370038971 9.27470086056482 5.88126105886883 1.2000703600027e-08 9.68864989045772 17.276833792508 0.56078851060425 0.575406788509223 SYCP2L other 0.000251557329231457 1 0.000148520747778742 5.88126105886883 0.56078851060425 0.0314848039664184 41.6548070240594 19.950425863991 2.08791568200272 0.037742646254195 -24.5563114963973 35.9297939071536 -0.683452612053756 0.494906962383318 BMP6 other 1 1 1 2.08791568200272 -0.683452612053756 0.000206851454173192 25.5839068750585 6.38753289292858 4.00528769149378 7.9988069373742e-05 -6.13562131458569 22.7450776940946 -0.269756005985362 0.787552509043506 RGPD3 other 1 1 0.758286897663074 4.00528769149378 -0.269756005985362 0.268271088467497 79.5125981223127 49.0690193658477 1.62042362268307 0.106308595795958 90.0114775973564 144.64822860653 0.622278464551434 0.534283927823214 RASSF3 other 1 1 1 1.62042362268307 0.622278464551434 1.48600061449707e-05 1309.54250587364 295.616600596405 4.42986795474831 1.36777615164611e-05 -1095.3994090953 801.303507812341 -1.36702185678168 0.1727471735674 HNRNPU essential 0.119964829608349 1 0.138883990438146 4.42986795474831 -1.36702185678168 2.20982156133246e-06 479.848888189069 96.8783921543341 4.95310540894027 1.28954126831277e-06 -130.046342267515 329.173606840961 -0.395069165828797 0.693103772839885 RANBP2 other 0.0191127466839645 1 0.0141914016577821 4.95310540894027 -0.395069165828797 4.59737154478479e-09 298.17351231951 46.7664921961096 6.37579382839225 7.88703282607281e-10 -1.17462520994363 128.314224778442 -0.00915428676728424 0.992702823215291 AHCTF1 essential 4.77620929787692e-05 1 1.02286928721338e-05 6.37579382839225 -0.00915428676728424 2.31243406451168e-05 262.465917341149 61.8063530281113 4.2465847681026 2.98247916695018e-05 -181.129371588373 200.275473744722 -0.904401164064886 0.366583047627681 MERTK other 0.183399145656422 1 0.294549642528 4.2465847681026 -0.904401164064886 4.71602088111502e-09 205.530183656458 44.5129229243681 4.61731493134418 6.00107168410735e-06 -453.678722202801 144.238355600522 -3.14534036604865 0.00184297818160084 TMEM87B other 4.89664448086173e-05 1 0.0627111990989218 4.61731493134418 -3.14534036604865 0.290575145593354 16.2080497944998 11.2557847313485 1.4399751044775 0.151045910846216 -14.3778824883016 47.0048167406775 -0.305881045502707 0.759933575682648 PTPRR other 1 1 1 1.4399751044775 -0.305881045502707 0.606469653011375 54.6081761839379 56.0459020194476 0.974347351301246 0.330749813362559 17.8773181444457 150.550952482359 0.118745965068142 0.9055642682334 NR4A2 other 1 1 1 0.974347351301246 0.118745965068142 0.598824697886938 0.655326774259822 2.12383534895404 0.308558182056137 0.757893821849258 -4.51275366950487 5.63925001597969 -0.800240041976733 0.424270099731807 CCDC148 other 1 1 1 0.308558182056137 -0.800240041976733 0.00849273846346111 196.595815198939 86.8199151508466 2.26440920677428 0.0243392430628502 -237.420721826094 211.250146630782 -1.12388429363342 0.26205667455415 PLA2R1 other 1 1 1 2.26440920677428 -1.12388429363342 0.700300384901603 15.4539033312576 35.8554981558961 0.43100512128058 0.666808539926495 -43.8385546388546 86.3815210610689 -0.507499220902375 0.61221886868727 SCN3A other 1 1 1 0.43100512128058 -0.507499220902375 0.899493365175241 0.291298279662634 11.3096327335339 0.0257566524506949 0.979470533398781 -18.650841000575 42.0816119355302 -0.443206430142183 0.657972656702008 CD96 other 1 1 1 0.0257566524506949 -0.443206430142183 1.99647747321271e-06 30.3870148224074 6.33241783247141 4.79864336598079 2.63292971729681e-06 -7.70770957002657 16.0176719576867 -0.48120036359764 0.630759556597525 SLC25A27 other 0.0173593716295845 1 0.0283279040057452 4.79864336598079 -0.48120036359764 0.821813254129884 -45.6792710867945 72.8928505533078 -0.626663256273514 0.531405586737054 -35.4347970170861 180.119336753405 -0.196729555281445 0.844186093762695 ADGRF1 other 1 1 1 -0.626663256273514 -0.196729555281445 0.0139375282549589 -3.27504445436881 26.3642733366857 -0.124222822777808 0.901230602973015 -185.06082381949 65.4342120409703 -2.82819671922722 0.00502922140325343 ADGRF4 other 1 1 1 -0.124222822777808 -2.82819671922722 8.27181777335367e-08 362.96228862995 61.7068757281641 5.88203963248601 1.2224747249588e-08 113.644931829447 265.968238422129 0.427287605857194 0.669518147722857 FAM49B other 0.000796162460685291 1 0.000151220123477404 5.88203963248601 0.427287605857194 0.0230843792455129 133.79814977078 48.4147163413965 2.76358429588437 0.006119413635215 94.2168658861243 208.676531862576 0.451497181044635 0.652001931213444 ASAP1 other 1 1 1 2.76358429588437 0.451497181044635 8.62533232739797e-29 317.426600638415 34.9660802581498 9.07812938410305 2.55777124663213e-17 -289.637186492475 67.653625410925 -4.28117761218608 2.59783056104432e-05 TRAPPC8 essential 1.3445168031948e-24 0.395467746307776 3.84100508106747e-13 9.07812938410305 -4.28117761218608 0.00203389429740061 -11.1052442528734 10.1388331727766 -1.09531778101367 0.274346347563087 -61.6035723615464 17.6516892782622 -3.48995336312713 0.000563406900368524 FAM81B other 1 1 1 -1.09531778101367 -3.48995336312713 3.04286712740717e-09 110.342125500199 24.2129539244786 4.5571525822236 7.93416759316035e-06 -99.2653350803586 43.7660571404371 -2.26808950968177 0.0241318989421625 INO80C other 3.19835763761768e-05 1 0.082134502924396 4.5571525822236 -2.26808950968177 0.000403914373045788 885.715216606592 250.366857850585 3.53766957899505 0.000475887064276286 -2161.46571058561 1481.04750084033 -1.45941687174733 0.145625899099573 LPCAT1 other 1 1 1 3.53766957899505 -1.45941687174733 7.53829981394511e-08 238.349560246506 40.4309660761717 5.89522297828493 1.14372934911136e-08 65.9031906323552 232.613475098181 0.283316306609232 0.777157261362548 PLEKHG4B other 0.000727521315043843 1 0.000141662317180933 5.89522297828493 0.283316306609232 2.26603338208686e-12 215.013613564112 40.7058768429516 5.28212705977719 2.61852956698969e-07 -169.29644712758 79.4358847991243 -2.13123385678517 0.0339665247611708 NMRAL1 other 2.75549659261762e-08 1 0.00302125941439271 5.28212705977719 -2.13123385678517 1.07223867585776e-13 103.490420346168 20.7356550065424 4.99094049903487 1.07404556502836e-06 -122.547397964099 40.4647984537716 -3.02849396628284 0.00269387808775171 UBALD1 other 1.36538872983727e-09 1 0.0118843141770388 4.99094049903487 -3.02849396628284 0.103656493278812 -133.974593210707 130.721567314974 -1.0248851506492 0.306324649504745 -546.151588288625 255.521555247153 -2.1373992803087 0.0334540124071362 C16orf89 other 1 1 1 -1.0248851506492 -2.1373992803087 1.92589590253682e-18 138.290218962196 16.9237287988497 8.17137999585499 1.16071496776922e-14 -37.4210926112856 34.0185494591709 -1.10002023032165 0.272295906274277 TMEM251 other 2.7513348863641e-14 1 1.69000099307199e-10 8.17137999585499 -1.10002023032165 6.56501906012309e-21 136.731495053954 15.7944464579769 8.65693491808939 4.80311025349083e-16 -55.6625586170789 31.1772544841987 -1.78535793282535 0.0753468614139874 ING1 other 9.70703718229799e-17 1 7.1230125059269e-12 8.65693491808939 -1.78535793282535 4.7131970149905e-05 25.2979609929077 8.24379905345265 3.06872606050634 0.00237447768185898 -27.2945668693009 15.4541787308213 -1.76616094227418 0.0785289530858119 ADPRHL1 other 0.361690738930371 1 1 3.06872606050634 -1.76616094227418 7.07970438698375e-21 600.126810628019 58.4097555890659 10.2744276974917 4.06670682305431e-21 117.633142150419 191.975279858117 0.612751507576178 0.540556410404632 CMTM7 other 1.04645110544007e-16 1 6.25622177658675e-17 10.2744276974917 0.612751507576178 1.75692024304196e-13 93.8957914330336 11.6691775839162 8.04647891917007 2.71485101148786e-14 49.2567698398517 38.3498098147211 1.28440714772316 0.200100468338376 FBXL2 other 2.22215272339946e-09 1 3.92974683912868e-10 8.04647891917007 1.28440714772316 8.69120076800009e-27 665.570836238741 59.1737036421741 11.247746807661 2.51250018666559e-24 -334.824681461681 194.46959859775 -1.72173277404787 0.086263261950563 UBP1 other 1.34357272672513e-22 1 3.91749029104899e-20 11.247746807661 -1.72173277404787 2.15614588335191e-07 402.236955043579 73.4818077482674 5.4739665145631 1.01735682061416e-07 -258.235908621284 303.874705847718 -0.849810476659731 0.396194683788148 RMND5A other 0.00202117115105408 1 0.00120241402628388 5.4739665145631 -0.849810476659731 0.7157977220095 -4.76445122435828 36.1808308873115 -0.131684406010398 0.89533346684254 117.056480312249 149.621242047723 0.782352015731246 0.434703610415613 CD8A other 1 1 1 -0.131684406010398 0.782352015731246 1.43757174077542e-05 160.084895554365 33.3609901712962 4.79856547219939 2.66688196348395e-06 49.3888906392763 130.80918877763 0.377564382906122 0.706055307264085 RPIA other 0.1162420509591 1 0.0286823155172699 4.79856547219939 0.377564382906122 5.69031382530312e-07 397.666143091096 72.1517636311342 5.51152353148438 8.42991580164979e-08 519.73135118449 256.674527397128 2.024865328301 0.0438838515886444 PTPRD other 0.00517021914167041 1 0.00100004091154971 5.51152353148438 2.024865328301 0.149074185614223 27.5023969209665 30.1840772810682 0.911155794655227 0.363054040271223 -130.838036735004 100.415705365459 -1.30296387660501 0.193735451311701 LURAP1L other 1 1 1 0.911155794655227 -1.30296387660501 2.94952645180463e-05 187.083141295661 54.5981875684635 3.42654490244877 0.000705832163438566 -197.307604056631 103.673859538401 -1.9031567353152 0.0580757623030225 CNKSR3 other 0.231213378556965 1 1 3.42654490244877 -1.9031567353152 2.36400563877739e-19 116.348488461437 11.9367838635625 9.74705496818073 1.9423793230992e-19 -28.1947708262225 46.0184227428653 -0.612684423883124 0.540598807089362 GTF2E1 essential 3.42520777002456e-15 1 2.96407084704938e-15 9.74705496818073 -0.612684423883124 3.5997080980906e-24 441.085491629865 52.2817275636302 8.43670460378409 2.00441050286226e-15 -133.358891308625 88.6717706432524 -1.50396107285553 0.133760191048729 CFDP1 essential 5.48523519987046e-20 1 2.94848784971038e-11 8.43670460378409 -1.50396107285553 4.04287008378138e-11 143.369451163959 84.8462372816417 1.68975614897398 0.0922161824891182 -667.23223691789 141.322799250172 -4.72133470648811 3.74977245177346e-06 ZDHHC7 other 4.67962212197694e-07 0.0581702200443617 1 1.68975614897398 -4.72133470648811 0.0848003100194539 -32.5250070685809 14.9128510002673 -2.1810052999254 0.0300365133906998 -22.1229426938799 24.8393554703282 -0.890640770462294 0.373906148756364 FAM92B other 1 1 1 -2.1810052999254 -0.890640770462294 3.54835938757386e-08 32.0608557062046 6.82387219747938 4.69833765615472 4.16210528682542e-06 -42.9102216834776 19.1286569003595 -2.24324279048945 0.025683338998197 C7orf31 other 0.000349371465300522 1 0.0440683707769075 4.69833765615472 -2.24324279048945 0.0458563806995413 100.21993346583 160.713451192245 0.62359393518311 0.533420742940377 -526.605599376843 306.175245426028 -1.7199483212436 0.08658770523863 TMPRSS11D other 1 1 1 0.62359393518311 -1.7199483212436 0.000173284775562286 18.2588865007927 16.5941163662451 1.10032291553252 0.272164286579917 -162.312255601702 45.8659787208432 -3.5388377208648 0.000472488722330087 JAZF1 other 1 1 1 1.10032291553252 -3.5388377208648 3.2610906347372e-12 432.112464760368 169.453069331014 2.55004212355852 0.0113176817587451 -1230.9902519743 283.664054968473 -4.33960606010201 2.01199468399031e-05 CMIP other 3.93972359582601e-08 0.30721146829848 1 2.55004212355852 -4.33960606010201 0.18920552343582 21.2202029011357 23.9352276969098 0.886567830891173 0.376097686968636 -69.3190025872427 52.6288816284557 -1.31712855075687 0.188908136665667 KCNJ16 other 1 1 1 0.886567830891173 -1.31712855075687 0.380600456501508 41.8140913847227 49.3373204117784 0.847514438071111 0.397450837387406 -35.35491028175 74.5852165665421 -0.474020347587349 0.635864283937562 PID1 other 1 1 1 0.847514438071111 -0.474020347587349 2.48719291552567e-13 387.699575173692 155.893121122411 2.48695755388245 0.0134817760872379 -1246.17028133228 241.889717571705 -5.15181171751489 4.95061447603436e-07 TRIP12 other 3.13162459993837e-09 0.00777741534184997 1 2.48695755388245 -5.15181171751489 3.98980422956925e-09 2.83005019506027 9.70354749421327 0.291651089124671 0.770774897731204 -79.7521321653287 15.0563947011864 -5.29689435938103 2.42767065373843e-07 FBXO36 other 4.16016887017185e-05 0.00382576618322639 1 0.291651089124671 -5.29689435938103 9.70032300598574e-23 698.299251528491 66.9157807107899 10.4354943499283 1.35593075726508e-21 -206.575897423076 224.417807099657 -0.920496907499597 0.358147184212293 CEBPG other 1.46115965439163e-18 1 2.09111641385421e-17 10.4354943499283 -0.920496907499597 8.54510416423996e-11 363.792069716872 58.821490060268 6.18467960169207 2.3351070631646e-09 -357.028725541381 202.685419679914 -1.76149190260064 0.0793039870105244 KCTD15 other 9.74996385139779e-07 1 2.97515990917802e-05 6.18467960169207 -1.76149190260064 1.65776288232333e-10 29.9155278340788 4.38733664384817 6.81860779387095 6.00334902953588e-11 -0.247864441802881 17.0322658505932 -0.0145526404987536 0.988399830019446 ZNF599 other 1.86597790034314e-06 1 8.08350946827007e-07 6.81860779387095 -0.0145526404987536 0.747240570427393 0.970460005773927 8.72929865923518 0.111172734907773 0.911561061267848 10.5361579902822 14.9843834607811 0.703142576260055 0.482566095293342 MCOLN2 other 1 1 1 0.111172734907773 0.703142576260055 0.104879280099273 3.09098429003925 3.81607947534199 0.809989495767051 0.418654266565682 33.1542672244885 15.7498155475033 2.10505749254594 0.0362034302321657 LGI4 other 1 1 1 0.809989495767051 2.10505749254594 0.00208070056236914 272.171282545616 79.867859957308 3.4077698174347 0.000753687656151299 124.805790563056 137.098143448918 0.910339027381197 0.363446790776559 DDAH1 other 1 1 1 3.4077698174347 0.910339027381197 1.15391725913365e-08 190.880104397677 61.0845683254482 3.12484985374212 0.00197217981132354 -290.828552467454 95.0424115731293 -3.05998709053883 0.00243544400400732 SREK1 other 0.000117064905939109 1 1 3.12484985374212 -3.05998709053883 1.31667467280245e-07 165.939523120147 40.883166110498 4.05887163121491 6.44439586006541e-05 -109.931815450815 66.2872206700652 -1.65841642385317 0.0983819174302049 CHD1 other 0.00125123594156417 1 0.616462941759289 4.05887163121491 -1.65841642385317 0.0241194146834101 14.0538340030124 8.20051922346658 1.71377367945142 0.0877054004674371 -14.7832793130286 14.794328939499 -0.999253117426579 0.318556956536982 CLCA3P other 1 1 1 1.71377367945142 -0.999253117426579 0.0106224395321882 10.879325654825 6.126481370287 1.77578694804965 0.0768985015846269 37.3028550043389 13.0625314569426 2.85571408017646 0.00462879104639077 ANKFN1 other 1 1 1 1.77578694804965 2.85571408017646 1.28952462745777e-11 81.7047089182117 12.9466285485583 6.31088693181905 1.12717965088113e-09 -56.5230612496767 27.6025865825521 -2.04774509376616 0.041548839637755 DGKE other 1.52408915719234e-07 1 1.45406174963666e-05 6.31088693181905 -2.04774509376616 2.36416422146342e-09 290.878870777162 69.2724365611207 4.1990564388552 3.63132982924814e-05 -277.647886225984 125.497746750602 -2.21237347613695 0.0277686625519328 HS2ST1 other 2.50412274337406e-05 1 0.355507190283393 4.1990564388552 -2.21237347613695 2.24681459049053e-09 779.392040038129 136.198306302451 5.7224796783255 2.76691258238571e-08 -432.747424286869 293.25140966289 -1.47568744779211 0.141184468543659 MSI2 other 2.38207282883806e-05 1 0.000336235217011512 5.7224796783255 -1.47568744779211 0.0102182827304101 179.642177615277 64.444407673002 2.78755262251461 0.00569816291411099 -44.4672432719673 196.591270524095 -0.226191341830293 0.821228293553177 CACNA2D1 other 1 1 1 2.78755262251461 -0.226191341830293 3.45839497363522e-12 52.2015934057018 8.9920652336942 5.80529522963167 1.78038632175108e-08 -39.8412462747514 16.3167903441293 -2.44173305132195 0.0152520467435491 ZUFSP other 4.17601193066453e-08 1 0.00021836438236277 5.80529522963167 -2.44173305132195 0.000474087840141743 15.104813126154 4.7112289871071 3.20613011328685 0.00150656139236127 -13.5577420503642 10.0796449608184 -1.34506146824276 0.179729897330701 GDPD1 other 1 1 1 3.20613011328685 -1.34506146824276 4.81255791868865e-11 221.08946008873 47.182602521782 4.6858258822553 4.41148859645296e-06 -293.235668199563 85.887745384439 -3.41417354579541 0.000737279265905951 NUS1 essential 5.55706062870978e-07 1 0.0466161999987184 4.6858258822553 -3.41417354579541 0.713503569603534 -15.6661151090365 34.8137298657478 -0.44999818087432 0.653085273658335 -93.6709183434536 117.781652186626 -0.795292956113665 0.427165754589891 SEMA3D other 1 1 1 -0.44999818087432 -0.795292956113665 2.33379174339724e-24 308.02430151068 37.7731024394859 8.15459365574082 1.28304967170856e-14 -216.027285155838 70.2668260261403 -3.07438513126341 0.00232309112632227 PPP2R5E other 3.56066606290117e-20 1 1.86683727233595e-10 8.15459365574082 -3.07438513126341 3.53160565766406e-15 72.5053393890379 11.9708461511762 6.05682659967307 4.60202089703885e-09 -77.5703079698872 31.1095165620552 -2.493459125768 0.0132450853955986 SLC5A10 other 4.69350391903554e-11 1 5.79532491564102e-05 6.05682659967307 -2.493459125768 0.510286242798151 1.76692310487321 2.97350276472937 0.594222788635618 0.552860674940817 -2.82490495050159 5.1309511987035 -0.550561648533198 0.582389426973142 AK5 other 1 1 1 0.594222788635618 -0.550561648533198 0.00173285397258797 245.577811997358 69.3810023587522 3.53955410917148 0.000478473966807094 123.745644039315 163.670733168396 0.756064579438259 0.450328035409794 CABYR other 1 1 1 3.53955410917148 0.756064579438259 1.05334622826384e-25 452.580935892865 43.886004680066 10.312648398783 5.08813393425794e-21 -162.732216507969 102.5069980167 -1.58752299507842 0.113653133102947 IMPACT other 1.62078384142957e-21 1 7.82351473731501e-17 10.312648398783 -1.58752299507842 0.0162359199555098 30.7314421861404 52.3371289635026 0.587182422780031 0.557633171656802 -283.890777117434 120.341721143162 -2.35903869764094 0.0191244972913161 ANKRD29 other 1 1 1 0.587182422780031 -2.35903869764094 0.0107535814204067 86.8415236160488 30.3408218031155 2.86220077292474 0.00455362674296102 -9.99547773091616 70.1217975023749 -0.142544516640173 0.886761606993233 SDHAF4 other 1 1 1 2.86220077292474 -0.142544516640173 0.0284471974018773 95.3145698186428 49.2517050063227 1.93525421721759 0.0540691358527477 -87.9835487859735 103.872262321261 -0.847036030791876 0.397772415052938 CHST9 other 1 1 1 1.93525421721759 -0.847036030791876 0.245837542020742 -198.908928650079 238.563458438434 -0.833777854966047 0.405137775679176 -723.774151159704 430.964926945713 -1.67942703896847 0.0942170883100268 THY1 other 1 1 1 -0.833777854966047 -1.67942703896847 0.192432900927415 -21.5417148768768 23.5417103533376 -0.915044597591134 0.360975730412023 -73.7268588989577 40.667261737321 -1.81292901831395 0.0709410022749052 DNAAF1 other 1 1 1 -0.915044597591134 -1.81292901831395 1.21624397647846e-06 127.19288111932 37.0065646341568 3.43703562804967 0.000679799712511584 -80.8596719631496 61.8045919570889 -1.30831171928602 0.191868035692836 C16orf74 other 0.0107588942159285 1 1 3.43703562804967 -1.30831171928602 0.000332335962041319 49.9400087980228 20.8952407783015 2.39001834570304 0.0175259782526092 -63.7230066609984 37.7803724380969 -1.68666962628303 0.0928092195856298 TBCEL other 1 1 1 2.39001834570304 -1.68666962628303 4.94037475999602e-05 116.952766361958 25.887414510427 4.51774611616203 9.32653484150601e-06 99.65114225079 42.8764887573668 2.32414419041411 0.0208545896372529 JPH3 other 0.378482110363295 1 0.096021580955024 4.51774611616203 2.32414419041411 3.58638398795749e-16 1151.54457360078 128.71870933793 8.94620975865739 7.10311805895275e-17 -174.210800626852 883.385399468893 -0.197208150294979 0.843818730898037 ANKH other 4.8846549915981e-12 1 1.06205821217461e-12 8.94620975865739 -0.197208150294979 1.70217052066758e-19 299.819130188084 29.7179002876192 10.0888396315466 2.05728849892601e-20 84.7766697876776 203.702954055445 0.416177910530461 0.677623148401624 OTULIN other 2.47018985959279e-15 1 3.15485191310303e-16 10.0888396315466 0.416177910530461 0.0363574116571786 69.4044500519019 35.6526830240076 1.94668238587168 0.0525984053949662 -33.5194939785473 64.6819407361086 -0.518220288338304 0.604724314595125 UBASH3B other 1 1 1 1.94668238587168 -0.518220288338304 0.145969097646132 203.205122047879 104.469586416264 1.94511272628379 0.0527917566262815 132.483659219753 188.418467367761 0.703135213180388 0.482572877504501 ROBO4 other 1 1 1 1.94511272628379 0.703135213180388 0.0340845926286792 80.0429350600499 38.4344492973293 2.08258311289533 0.0382235908188262 -23.4126454230367 69.3193136792138 -0.337750681309144 0.735811592842074 ROBO3 other 1 1 1 2.08258311289533 -0.337750681309144 4.51722007382052e-12 110.317198517229 27.4292488180393 4.02188186957118 7.4782149443712e-05 -175.54128364715 49.1756365412488 -3.56967994709951 0.00042216045829908 TBRG1 other 5.41976064456986e-08 1 0.711178241209701 4.02188186957118 -3.56967994709951 0.23670199191942 11.1238918331107 58.1865453531976 0.191176358135505 0.848530049511755 -142.93938207272 104.203332309176 -1.37173523058373 0.17127626915835 NRGN other 1 1 1 0.191176358135505 -1.37173523058373 0.0434882578712968 24.3220542362586 12.9589517205653 1.87685352648244 0.0616494711941293 -130.668699758767 91.093751038596 -1.43444197070558 0.152638677544288 RETREG1 other 1 1 1 1.87685352648244 -1.43444197070558 7.92901782386265e-06 45.9475883108141 9.27050374736365 4.95632055851126 1.29116151442467e-06 32.4608556338112 63.3701052236711 0.512242413346757 0.608912892430476 CDH12 other 0.0655174742785771 1 0.0142079413047291 4.95632055851126 0.512242413346757 0.826279463871722 -2.92572020119906 21.2981466479321 -0.137369708715154 0.890840577434972 -45.984461690885 74.606201992239 -0.616362453294012 0.538172722792772 GPR15 other 1 1 1 -0.137369708715154 -0.616362453294012 5.35712840667521e-24 633.54923539756 60.6950544300964 10.4382348998011 1.29328671185707e-21 -434.477266557182 221.956781552811 -1.95748588314165 0.0513320234647504 TOMM70 other 8.15408514780034e-20 1 1.99463609569717e-17 10.4382348998011 -1.95748588314165 0.426076770496588 -15.5528408210107 82.1286049687777 -0.189371788634707 0.849945310027441 -391.359419503516 301.040049624601 -1.30002443193703 0.194713742151525 ABI3BP other 1 1 1 -0.189371788634707 -1.30002443193703 0.376068695137772 40.8635494599175 38.0302205432549 1.0745020374899 0.283557028432413 170.828539877406 157.390702952175 1.0853788481351 0.278722025820077 ANGPT1 other 1 1 1 1.0745020374899 1.0853788481351 0.27235986166042 53.0376037808795 32.8625252104693 1.61392356312238 0.107716401079348 22.0160215821989 72.4992252613449 0.303672508262477 0.761612151636536 PITPNC1 other 1 1 1 1.61392356312238 0.303672508262477 1.17082204791719e-11 152.218430232252 46.5012047599284 3.27342981796083 0.0012015366460309 -276.038953945528 74.8385722285024 -3.68845831401896 0.000272968953996391 CC2D1B other 1.38508248268604e-07 1 1 3.27342981796083 -3.68845831401896 1.61593504625417e-08 193.689050473759 32.7062816014719 5.9220749345301 9.53129963901756e-09 -66.3279178498696 127.158835241179 -0.521614701204735 0.602361536024799 CERS3 other 0.000162514587601782 1 0.000118474054512988 5.9220749345301 -0.521614701204735 0.59297130962126 32.7103613744703 32.7722490724425 0.998111582215934 0.319122239680529 0.625846888839369 73.5141759588311 0.00851328169943512 0.993213776141184 PRKCA other 1 1 1 0.998111582215934 0.00851328169943512 2.98134667148353e-05 142.258851745655 32.9609976368291 4.31597530247997 2.22700330195745e-05 -30.5046214729603 80.4259023790248 -0.379288519875108 0.704769554274975 LRRK1 other 0.233588511710734 1 0.222188119436295 4.31597530247997 -0.379288519875108 0.521925132781312 6.14873308165324 49.8140405593676 0.123433734999378 0.901855478877367 -117.587728119488 109.155640170108 -1.07724830284756 0.282330890773864 CEP112 other 1 1 1 0.123433734999378 -1.07724830284756 0.463782175928374 3.61224763603657 6.87518363872489 0.525403803862106 0.599738551104004 -14.247029456005 15.0419108480336 -0.947155557557867 0.344415935975584 ABCA9 other 1 1 1 0.525403803862106 -0.947155557557867 0.729464168847195 -6.31220952380953 11.2309853225661 -0.562035239341518 0.574565289048646 -16.9748285714286 24.57745359945 -0.690666691841847 0.490377256153564 ABCA6 other 1 1 1 -0.562035239341518 -0.690666691841847 0.36787739883029 4.39180545838883 7.61568334942392 0.576679105062981 0.564643926921438 -18.363820966201 16.7760575952041 -1.09464460657615 0.27466256340282 ABCA10 other 1 1 1 0.576679105062981 -1.09464460657615 2.35827168828565e-05 169.576886542164 39.3689599928064 4.30737531733503 2.32065125918151e-05 -60.54284863507 86.6476189606612 -0.698724897017158 0.485329863700585 ABCA5 other 0.186751534995341 1 0.231206484952253 4.30737531733503 -0.698724897017158 0.504510966428418 -2.99267394595332 27.9938605450202 -0.106904652937756 0.914943718485464 55.7802394898812 52.2894046953565 1.06675988787523 0.287029688895803 ENPP3 other 1 1 1 -0.106904652937756 1.06675988787523 0.00872267960542384 44.726352547588 26.5515947566198 1.68450720032313 0.0932349664163859 -42.3418680276594 42.6130975206975 -0.993635067413102 0.321286929703497 C4orf19 other 1 1 1 1.68450720032313 -0.993635067413102 0.0449261534447849 1286.72986255523 722.800689012148 1.78020010511308 0.07617190602145 -171.604570119571 1048.71794661654 -0.163632720001804 0.870143156953737 UCHL1 other 1 1 1 1.78020010511308 -0.163632720001804 0.0268271750778282 115.503649342469 45.6471800331107 2.53035673307064 0.0119591886649223 -96.6936165136562 127.784285904566 -0.756694110149589 0.449888064691213 MIA3 other 1 1 1 2.53035673307064 -0.756694110149589 0.883273785446621 -7.63056706048524 22.5833452297836 -0.337884710296232 0.7357106971268 -24.8133271620255 63.219603958688 -0.392494188641868 0.695000495006978 DISP1 other 1 1 1 -0.337884710296232 -0.392494188641868 0.0117699262897466 39.9404393975261 13.570132579164 2.94326080931973 0.00353890504806912 80.298780854325 127.437396727379 0.630103744398551 0.529175858967605 TNIK other 1 1 1 2.94326080931973 0.630103744398551 4.34966320391838e-05 15.1472679759183 3.48671602892987 4.34427921581193 1.9771689163304e-05 8.95890521849864 5.87688468222612 1.52443100433699 0.128567193465692 TDH other 0.335141549861911 1 0.198072782037979 4.34427921581193 1.52443100433699 0.0124614864007243 63.9501791805957 40.6700974011212 1.57241273729609 0.11702160912023 -72.6287697718752 68.5497386245851 -1.05950469293004 0.290313396913683 FAM167A other 1 1 1 1.57241273729609 -1.05950469293004 1.32281384322127e-18 117.367441126747 21.9397495111108 5.3495342354437 1.87740853206437e-07 -121.168601000671 36.9796039493639 -3.27663328051288 0.0011874551593541 NEIL2 other 1.89374029795557e-14 1 0.00218380160449728 5.3495342354437 -3.27663328051288 0.433550928130578 0.260096202361293 27.9897168360631 0.00929256283243901 0.992592867879302 -62.1897097110565 55.2581989215768 -1.12543859417707 0.261445041901497 PGM5 other 1 1 1 0.00929256283243901 -1.12543859417707 0.896482439615919 7.47298555706628 16.5175190405126 0.452427845776187 0.651320090660418 -2.72359354557352 45.7765486075122 -0.059497573067939 0.952599327835036 WNT3A other 1 1 1 0.452427845776187 -0.059497573067939 0.0968593265487915 156.62523106521 72.3156324868375 2.16585578635046 0.0311879610584208 28.8569877970781 202.553446919497 0.142466041609981 0.886816986698243 OBSCN other 1 1 1 2.16585578635046 0.142466041609981 3.91314537543263e-09 137.892216469443 43.3164200289763 3.18337056426178 0.00162610790481374 -182.6358576582 72.7319550555421 -2.5110813743248 0.0126206896169525 LONRF1 other 4.08219325565132e-05 1 1 3.18337056426178 -2.5110813743248 0.000321344840182976 705.273938368848 201.552630650594 3.49920482849709 0.000545335940892062 -925.560334984593 556.620500851237 -1.6628211385839 0.0975043197891171 ENAH other 1 1 1 3.49920482849709 -1.6628211385839 1.56724790687019e-10 120.884823295172 17.2486781862982 7.0083528714217 1.900014628131e-11 39.9665140202421 48.5980940115586 0.822388507885441 0.411576162161399 CCSAP other 1.76566149187995e-06 1 2.59427997325007e-07 7.0083528714217 0.822388507885441 3.11517770844526e-13 102.975615229909 50.2807189612227 2.04801397747166 0.0415258661095011 -358.170257817899 73.1202617873663 -4.8983722030353 1.6671045940377e-06 SH3RF1 other 3.90580981084866e-09 0.025998496144018 1 2.04801397747166 -4.8983722030353 0.176043812606567 -223.490826065693 119.538819917607 -1.86960876993545 0.0626124778023655 -204.898027259239 211.399778154351 -0.969244287047624 0.333284378185111 GBP5 other 1 1 1 -1.86960876993545 -0.969244287047624 4.55773606704968e-15 763.804339693226 111.546220696241 6.84742463640427 4.96365127317923e-11 -87.7732481510252 154.972576833486 -0.566379226211972 0.571601317006782 BUB3 essential 6.04173493048106e-11 1 6.69745466290073e-07 6.84742463640427 -0.566379226211972 0.69601652623632 0.866099547057125 3.35726219494329 0.257977928671059 0.796619021566528 -5.94700442905358 8.9731378929519 -0.662756384667258 0.508047804118807 CCDC173 other 1 1 1 0.257977928671059 -0.662756384667258 0.262930217870079 49.8547576856559 30.7193470754695 1.62291072017826 0.105766887112264 34.0295354747072 49.4127065517754 0.688679852803663 0.491611733322723 FAM69A other 1 1 1 1.62291072017826 0.688679852803663 2.726220681215e-15 1824.6167057985 224.446919345375 8.12939073131503 1.56983961768645e-14 -282.870519513454 650.76432995245 -0.434674284520363 0.664146064078611 ATP5G3 other 3.6315985694465e-11 1 2.28066299657488e-10 8.12939073131503 -0.434674284520363 7.93559588271081e-14 62.1050270017241 8.12772001671274 7.64113759750824 3.69629531170148e-13 -8.2041584775302 18.2267831618754 -0.450115547250854 0.652985657000214 SRSF12 other 1.01472464552223e-09 1 5.26056748761355e-09 7.64113759750824 -0.450115547250854 0.0305705724816671 -48.4885583268094 90.0603305381599 -0.53840084793231 0.590742278598899 -326.518629534355 138.39543696469 -2.35931643915155 0.0190182288873555 PDLIM3 other 1 1 1 -0.53840084793231 -2.35931643915155 0.00104020886189157 -49.2045651120306 47.4805641876065 -1.0363096132896 0.300981533925829 -251.943913805317 72.9632390732736 -3.45302534543869 0.000643026969689122 SORBS2 other 1 1 1 -1.0363096132896 -3.45302534543869 2.50801130018483e-10 217.741123550528 32.8362448462233 6.63112132858797 1.82912554735477e-10 23.2256159051194 108.890637048328 0.21329304827936 0.83126055941625 ELOC other 2.79919141213629e-06 1 2.42523756323769e-06 6.63112132858797 0.21329304827936 0.504818646664178 -7.06263542544527 11.841227218996 -0.596444548763931 0.551381751186696 29.9381281440423 39.2675466195637 0.762414021789857 0.446483430621886 LY96 other 1 1 1 -0.596444548763931 0.762414021789857 1.93169150413232e-06 566.296353415379 199.500285368832 2.83857415225459 0.00497849873398373 -777.147328872929 326.14667463749 -2.38281543031743 0.0180767173819368 CXADR other 0.0168134428519677 1 1 2.83857415225459 -2.38281543031743 3.35818555103531e-08 274.066985340002 75.3402658951911 3.63772256553047 0.000346531052560157 -290.292941615772 123.167629272273 -2.35689314904368 0.019352989699197 BTG3 other 0.000331217840898613 1 1 3.63772256553047 -2.35689314904368 2.86235922616016e-05 352.958380648394 94.4062312184245 3.73871910882414 0.000238781590777959 -79.5919830381909 154.337014205382 -0.515702493325903 0.606607307269738 C21orf91 other 0.224666575661311 1 1 3.73871910882414 -0.515702493325903 0.00920597333513395 94.3770251664135 35.8089089851313 2.63557387927124 0.00903233394259668 -3.16160957379601 58.5013105728032 -0.0540433973673373 0.956952460117686 CHODL other 1 1 1 2.63557387927124 -0.0540433973673373 0.305885695400447 -6.55227492198624 37.7308799474332 -0.173658152980129 0.862303830120897 66.3352609554806 57.0767155247194 1.162212302261 0.24648745732899 NCAM2 other 1 1 1 -0.173658152980129 1.162212302261 5.04147288502401e-07 113.16351754194 24.7416959905249 4.5737979152794 7.31567354742471e-06 -57.9511802750196 54.6794738388239 -1.05983427064129 0.290170690198649 L3MBTL4 other 0.00460387303860392 1 0.0759879011371005 4.5737979152794 -1.05983427064129 0.913193218577006 0.107050260311536 7.69949477638003 0.0139035434688439 0.988917089844177 -8.35961418680563 21.0004725479705 -0.398067908601111 0.690891242645345 PDE1C other 1 1 1 0.0139035434688439 -0.398067908601111 4.94581293362944e-12 161.493782645511 24.7019096618363 6.53770436603182 3.36456771583784e-10 -124.500430960416 75.4829539049236 -1.64938472224118 0.100295328093056 RABGEF1 other 5.92755680095488e-08 1 4.41902323798141e-06 6.53770436603182 -1.64938472224118 3.70800143474635e-13 133.531496846691 26.1635863192098 5.10371533999714 7.44294534679813e-07 -88.9683529957304 37.9558447668681 -2.34399612344793 0.0200125193638821 MRPL39 essential 4.63908059501116e-09 1 0.00832419007585902 5.10371533999714 -2.34399612344793 0.644907190223841 -32.2494548877159 60.3646874917132 -0.534243714790092 0.593738040734043 29.4864921463555 87.5718137369315 0.33671213245547 0.73667016303784 JAM2 other 1 1 1 -0.534243714790092 0.33671213245547 3.40998510350093e-11 435.23531015882 95.247411167508 4.56952377837744 8.33452708138969e-06 -304.303268832696 138.176621072228 -2.20227753777268 0.0287338892102326 ATP5J other 3.95899270516458e-07 1 0.0861540064403252 4.56952377837744 -2.20227753777268 1.20951419041724e-12 166.700953989646 37.4147880311217 4.45548305260968 1.36064916619343e-05 -157.868283612573 54.2781050414277 -2.9085076476432 0.00402208900646236 GABPA essential 1.48564442576867e-08 1 0.138201135810267 4.45548305260968 -2.9085076476432 0.622466199409736 218.236750755297 224.100855387939 0.973832743197298 0.331254686255768 190.759005030769 325.476237897139 0.586091956399761 0.558440139016785 ADAMTS1 other 1 1 1 0.973832743197298 0.586091956399761 0.315099110837409 -33.2061123012474 63.4359199600939 -0.523459143055489 0.601201507531185 -135.841854248749 91.9285181491453 -1.47769002463804 0.140974833015675 ADAMTS5 other 1 1 1 -0.523459143055489 -1.47769002463804 5.76714450016003e-20 75.2885754382626 7.65776655857123 9.8316623864687 1.0029877558507e-19 9.53352976855931 22.274511272192 0.428001748368826 0.668987294220856 TSEN2 essential 8.42464468583377e-16 1 1.53356827869572e-15 9.8316623864687 0.428001748368826 0.0733330225466505 32.8333852159616 78.5772407806294 0.41784853845435 0.676388741958334 -277.352793502956 153.181846055904 -1.8106113788558 0.0713084170149737 SLFN13 other 1 1 1 0.41784853845435 -1.8106113788558 2.56191166630693e-10 153.710104415028 22.2994283710288 6.89300648687151 3.78007387448396e-11 180.349858861576 60.9475350940479 2.95910012740103 0.00335600311287144 WNT7A other 2.85781246376539e-06 1 5.11481795956425e-07 6.89300648687151 2.95910012740103 1.10624746351479e-08 153.383622461563 34.7105667768374 4.41893165985169 1.43209111624861e-05 -253.447350571406 94.8689559017599 -2.67155201785776 0.00800379461390328 XPC ts 0.000112405804767738 1 0.145142434631797 4.41893165985169 -2.67155201785776 9.00014346123851e-29 114.420091574589 9.87965941866047 11.5813801595706 1.69542784910351e-25 -34.2712634460189 27.0240336324883 -1.26817720522735 0.205815099740083 CCDC174 essential 1.40285236130325e-24 1 2.65164915599788e-21 11.5813801595706 -1.26817720522735 0.0460334207872365 -88.2844569955853 64.6634638006972 -1.36529118309671 0.17328551461403 -429.792189884753 176.875289571486 -2.42991653003653 0.0157472563086448 FGD5 other 1 1 1 -1.36529118309671 -2.42991653003653 1.32327856827577e-10 210.311941738981 35.5406779809651 5.91749943126073 9.769175251456e-09 -83.1157380521771 93.2497893217502 -0.891323601444219 0.373540475646535 FLCN other 1.4957017657221e-06 1 0.000121352694973586 5.91749943126073 -0.891323601444219 2.28861211665529e-11 185.570838272487 29.6167820760952 6.26573264427224 1.44608387281118e-09 -107.123353281919 79.5371979734351 -1.34683338125259 0.179154988367089 DPH3 essential 2.67607414800503e-07 1 1.85807316817509e-05 6.26573264427224 -1.34683338125259 7.70597722027565e-31 92.6115377047447 8.18212734588151 11.31876024288 1.3569968734341e-24 -61.7201215151967 21.9734703412801 -2.80884723972104 0.00533238892406169 OXNAD1 other 1.20891370631684e-26 1 2.11691512255719e-20 11.31876024288 -2.80884723972104 2.98517179269917e-16 305.606507199856 55.7667870521714 5.48008094699723 9.74861656273016e-08 -300.321898363926 88.2369931164158 -3.40358264438698 0.00076600952675232 CXXC1 essential 4.07505801421364e-12 1 0.00115326133937098 5.48008094699723 -3.40358264438698 2.19617147751455e-09 138.918898506365 24.997825753041 5.55723925267641 6.5712605697161e-08 -6.36179251332323 39.5528072440844 -0.160843008539544 0.87233732868759 SKA1 essential 2.33013793764294e-05 1 0.000783951385967131 5.55723925267641 -0.160843008539544 3.54301766408306e-12 861.798730040043 138.143128652589 6.23844803897088 1.72381665557156e-09 -451.384268416229 304.123732342052 -1.48421257670398 0.138932088379743 PPP4R1 other 4.27571371701544e-08 1 2.20769199079049e-05 6.23844803897088 -1.48421257670398 0.740446298502001 -204.483078954289 296.593914282134 -0.689437878215448 0.491150998513113 -398.129534739641 657.253267419161 -0.605747516939669 0.545200881957561 APCDD1 other 1 1 1 -0.689437878215448 -0.605747516939669 0.477276389479644 5.07778916577535 30.2400065757115 0.167916271878518 0.866779187401161 -69.8161526793795 67.5065774372421 -1.03421259571757 0.30199409071201 PIEZO2 other 1 1 1 0.167916271878518 -1.03421259571757 0.0256647257244173 11.6338335485595 4.73270330252018 2.45817935435852 0.0145857713060458 2.41571621901581 12.2963542972558 0.196457922455514 0.844397930152261 CCDC144B other 1 1 1 2.45817935435852 0.196457922455514 9.17143310986311e-10 84.7351514739597 30.6310830394013 2.76631261666339 0.00608592633833083 -314.172140635611 68.9861542436837 -4.5541332761621 8.16914735447384e-06 MPPE1 other 9.92807634142681e-06 0.125927406469214 1 2.76631261666339 -4.5541332761621 0.00269715486521772 49.4737631967982 15.2129302548705 3.25208637441553 0.00129009958207786 -3.44314737109352 45.9884798569405 -0.0748697800363126 0.940373354551835 USP43 other 1 1 1 3.25208637441553 -0.0748697800363126 6.48022098401867e-05 494.757053026748 111.304743833778 4.44506708326482 1.27897895044129e-05 672.480573543981 560.712247914424 1.1993327701424 0.231438471722455 RAB6B other 0.491135948378775 1 0.130225636733932 4.44506708326482 1.1993327701424 2.89337294188345e-11 125.749801133563 18.9832006442519 6.62426760850992 1.87142570881712e-10 -29.0239094413455 42.3620317069342 -0.685139694010347 0.493841376379738 EME1 other 3.36962212811746e-07 1 2.48076191960798e-06 6.62426760850992 -0.685139694010347 0.0504781271932756 50.033193560235 22.1379454326079 2.26006490586696 0.0246082443868256 149.206124510284 111.854531114099 1.33393008780381 0.183342589744245 EPHB1 other 1 1 1 2.26006490586696 1.33393008780381 0.00165550191248006 215.946991938113 94.2418381725666 2.29141319954617 0.0227303960922312 -609.36932007938 309.508392178528 -1.96882971666852 0.0500225575329617 ACSS1 other 1 1 1 2.29141319954617 -1.96882971666852 1.01077681528063e-15 324.416823285473 41.1895461122993 7.87619320691181 8.19129860956421e-14 -121.08401066722 90.9928865722308 -1.33069754382506 0.184407113186187 ANKRD40 other 1.36111205945689e-11 1 1.1766800452639e-09 7.87619320691181 -1.33069754382506 8.25307673745586e-18 94.2787408259394 10.8203814059172 8.71307001936018 3.08183810426048e-16 -3.08519096651668 30.8348333025963 -0.100055380103414 0.92037488648292 ZNF18 other 1.16558202763089e-13 1 4.57837868768938e-12 8.71307001936018 -0.100055380103414 6.93397411024883e-07 384.76699526973 78.2504558515017 4.91712145421764 1.6415525229369e-06 -336.625226862868 243.357371859065 -1.38325469366844 0.167888433475703 VOPP1 other 0.00625652483967752 1 0.0179290366555168 4.91712145421764 -1.38325469366844 0.075898261476643 -45.6644847628879 41.0438321660349 -1.11257848872788 0.266882770765402 -148.091292690687 65.435955096609 -2.26314863857411 0.0244237893671326 DKK2 other 1 1 1 -1.11257848872788 -2.26314863857411 0.00564084408132584 5.88655107659435 18.0858654238387 0.325477987292517 0.745073304069174 -68.7016878908185 28.5463469497633 -2.40667178927384 0.0167755495403708 CYP2U1 other 1 1 1 0.325477987292517 -2.40667178927384 5.49645336461812e-11 58.8040845525825 10.173274455765 5.78025146262122 2.03327664445991e-08 -81.3377269420418 27.0978292530329 -3.00163257294635 0.00293387829058946 RSPH10B other 6.32696746801192e-07 1 0.000248608735318113 5.78025146262122 -3.00163257294635 2.95115644432222e-08 47.7184998596876 8.40459936450446 5.67766502484572 3.49916309211192e-08 -20.2868537276337 22.1298691936062 -0.916718194316986 0.360102398599009 FBXL18 other 0.000292459603632332 1 0.000423083809467252 5.67766502484572 -0.916718194316986 0.0506460292988832 -624.983855149001 304.106217866721 -2.05514987340019 0.0408674396091176 -2224.84630101848 1351.83109882451 -1.64580198144065 0.101017469796478 PROM2 other 1 1 1 -2.05514987340019 -1.64580198144065 0.000117181616867004 37.8264035773707 11.8948092564899 3.18007651587454 0.00164468156719262 -29.7289050075842 20.6560001698899 -1.4392382243935 0.151245638733024 AK9 other 0.860933339121876 1 1 3.18007651587454 -1.4392382243935 0.00203567404163769 251.541122118563 81.1934436655535 3.09804721616063 0.0021512119129704 -332.473315137808 325.919632928218 -1.02010827684945 0.308580251175369 KLF10 other 1 1 1 3.09804721616063 -1.02010827684945 0.980100103299859 -5.85179137140085 43.2584937804276 -0.135274968220195 0.892497169585478 -21.4619157988902 110.982393727432 -0.193381265965481 0.846808522373165 PTPRN2 other 1 1 1 -0.135274968220195 -0.193381265965481 2.77640941860899e-14 1052.19270432662 129.613648639639 8.11791593994858 1.63709094615926e-14 -169.779966161256 518.102495866522 -0.327695711786333 0.743392906424137 AZIN1 other 3.59933717028469e-10 1 2.37787459929633e-10 8.11791593994858 -0.327695711786333 4.0667114719357e-17 311.556184809044 35.1881761405817 8.85400208195883 1.09462212347544e-16 -145.330633232285 140.79439602899 -1.03221887611465 0.302883156176283 ATP6V1C1 essential 5.66736910728959e-13 1 1.63394244371178e-12 8.85400208195883 -1.03221887611465 2.95277703839671e-13 94.1462250335137 12.5282323210194 7.51472535160119 8.48080101124839e-13 -28.6096018880465 43.6310538141105 -0.655716499764991 0.512566967020856 OTUD6B other 3.70662101629939e-09 1 1.19638659865681e-08 7.51472535160119 -0.655716499764991 7.3056790350062e-10 202.509401350407 37.0041809499118 5.4726086661537 1.00972273875149e-07 -106.70187552503 69.4630995232743 -1.53609436171616 0.125681914330862 CDK19 other 7.95369276541125e-06 1 0.00119369422175201 5.4726086661537 -1.53609436171616 6.6454862197436e-08 112.485396668624 32.8143237509868 3.42793584662067 0.000702739144268879 -193.805732372138 61.5980296818102 -3.14629759057649 0.00183786793683524 GTF3C6 essential 0.000643615340382167 1 1 3.42793584662067 -3.14629759057649 2.92333946435e-20 363.856254541483 37.0107253029682 9.83110305358708 1.25428234744694e-19 8.48993709296786 123.47333782841 0.0687592742067624 0.945233483758147 TTC39B other 4.28620032262997e-16 1 1.91717056807265e-15 9.83110305358708 0.0687592742067624 5.72313183558905e-19 355.779461486721 53.1279448738893 6.69665394231304 1.21857537650655e-10 -152.595041903094 89.0208098430686 -1.71415023264895 0.0876403026653637 AGPAT5 other 8.24703297508382e-15 1 1.62509212210913e-06 6.69665394231304 -1.71415023264895 4.36551430876876e-33 529.997073279047 49.8278934253665 10.636553882674 2.46835535603297e-22 -227.20497361463 79.3680728250099 -2.86267469433924 0.00452637161506224 MMS19 essential 6.88005055061957e-29 1 3.81854573578301e-18 10.636553882674 -2.86267469433924 1.04099587005404e-16 349.367574341232 52.0626189325573 6.71052631435633 1.11668259588476e-10 -183.145999439379 82.9276424677501 -2.20850363026543 0.0280401676568341 PI4K2A other 1.43563740439152e-12 1 1.48987791942944e-06 6.71052631435633 -2.20850363026543 5.98290799130564e-05 54.6658191747864 103.894926694921 0.526164471296158 0.59920111472853 -601.611591767701 165.488435115616 -3.63536939211127 0.000331675896315602 MARVELD1 other 0.454940323658881 1 1 0.526164471296158 -3.63536939211127 6.80303372357161e-10 86.4812365455088 28.7568951218211 3.00732176332505 0.00288126682733244 -174.725052794361 45.8052546345046 -3.81451984468923 0.000168777293052235 ZFYVE27 other 7.42074918567191e-06 1 1 3.00732176332505 -3.81451984468923 0.0879404441168444 -32.5167634891365 50.1450169067058 -0.648454532374244 0.517236065326558 -172.929348467979 79.8732011343004 -2.1650484269087 0.0312503796715625 GOLGA7B other 1 1 1 -0.648454532374244 -2.1650484269087 0.227730412135516 -65.5275994865209 48.5914378436426 -1.34854209701255 0.178614153501723 -120.982020012508 71.1565577881824 -1.70022305424955 0.0902405017149953 GPR78 other 1 1 1 -1.34854209701255 -1.70022305424955 1.39454031997216e-11 24.8186777920408 16.0353953529807 1.54774342919007 0.12285537544348 -102.860433604336 23.4819875008083 -4.38039725558987 1.69668327963291e-05 TRMT44 other 1.64667320982312e-07 0.259779176944594 1 1.54774342919007 -4.38039725558987 5.05546947047203e-13 260.871161443245 41.5740988366212 6.27484825271673 1.36770103653088e-09 -82.6288820693682 66.9716092056361 -1.23378970655545 0.218342403309884 SLC25A28 other 6.29608167852586e-09 1 1.75913707318602e-05 6.27484825271673 -1.23378970655545 2.97027350877913e-07 243.636763547453 69.0469843674415 3.52856487186915 0.000513705080789962 -227.866719864142 112.879258811858 -2.01867661306973 0.0447985059287255 HSPA13 other 0.00275968111700669 1 1 3.52856487186915 -2.01867661306973 0.190552606702993 -44.3879221270806 26.4854525467517 -1.67593595196185 0.0952460229806785 -10.056614389917 43.2988968332657 -0.232260291264297 0.81656312147516 SAMSN1 other 1 1 1 -1.67593595196185 -0.232260291264297 4.7020741965514e-07 91.5071970045727 44.0224722907622 2.078647387184 0.0388705378920167 -244.063437989136 71.9687338813016 -3.3912426247719 0.00083192152975977 USP25 other 0.0043038085121035 1 1 2.078647387184 -3.3912426247719 3.8353628647351e-12 93.4538494964692 20.694556706786 4.51586621644448 9.39069752322472e-06 -103.242480796231 33.1573861866199 -3.11370987493257 0.00204397216991869 ZCCHC10 other 4.62237932457875e-08 1 0.0966490589090288 4.51586621644448 -3.11370987493257 2.96429975954115e-13 51.3525295618392 11.2433501854111 4.56736904170005 7.6319947998777e-06 -56.5203518838063 19.9006362588922 -2.84012788076317 0.00486619440464415 C16orf87 other 3.72078905817605e-09 1 0.0790750981215329 4.56736904170005 -2.84012788076317 1.26596650513604e-12 499.687860976458 108.711816185092 4.59644478872188 6.58621170364971e-06 -296.025744593255 160.005611716683 -1.85009601486615 0.065384168406541 MOV10 other 1.55397388505449e-08 1 0.0686612570105483 4.59644478872188 -1.85009601486615 1.07906031652858e-12 438.432101079945 396.58667313502 1.10551395389597 0.269913828305346 -3038.57774793668 583.709254986717 -5.20563572014261 3.81614385899256e-07 RHOC other 1.32821534361502e-08 0.00600279429019529 1 1.10551395389597 -5.20563572014261 8.45162481524806e-05 4.41847078336839 12.8967898876017 0.342602370192608 0.732162220742322 -59.59335077709 18.9819177671895 -3.13947997815574 0.00187890856456208 PPM1J other 0.632097019932403 1 1 0.342602370192608 -3.13947997815574 4.46158366002269e-05 584.830827390668 171.12469252457 3.41757123862589 0.000728144904440419 -965.817101984708 520.846019595047 -1.85432366889474 0.0647712042011773 DBI other 0.343274246802146 1 1 3.41757123862589 -1.85432366889474 1.55497973945077e-05 850.745646483026 287.280070580456 2.9613806650913 0.00333304047981718 -416.226229663397 422.828217210313 -0.984386123540964 0.32580050351886 SLC16A1 other 0.125315817202338 1 1 2.9613806650913 -0.984386123540964 1.48666454373357e-15 124.966494645884 22.3937304340259 5.58042328025907 5.8866035183351e-08 -95.4475349097328 40.1095710985915 -2.37966979689505 0.0180308741375859 HEATR3 other 1.99450915187295e-11 1 0.000704508709074345 5.58042328025907 -2.37966979689505 9.12039902412802e-07 30.6373899412589 6.86865131862298 4.46046662147366 1.2027256524819e-05 -33.8795664183953 23.097183433151 -1.4668267460598 0.143591282964423 TRIM74 other 0.00814360428864391 1 0.122726125579253 4.46046662147366 -1.4668267460598 7.52092551112772e-12 303.041838983306 44.4408968011282 6.81898568202641 5.95264268100496e-11 -123.836289129713 132.435860859451 -0.935066139383017 0.350586666577259 NIFK other 8.95967856140646e-08 1 8.01582863424127e-07 6.81898568202641 -0.935066139383017 7.55505365272914e-33 520.633270556461 60.4953037814063 8.60617664534286 6.15312449517571e-16 -530.68323693576 114.94444299859 -4.61686727162853 6.01308062498694e-06 OXA1L other 1.18992095030484e-28 0.0928780433335483 9.10600894041053e-12 8.60617664534286 -4.61686727162853 0.119521521002945 -105.649029126214 56.1364696408623 -1.88200344271936 0.0609031441326253 -185.005796199485 106.039267314713 -1.74469138541299 0.0821680660944411 SLC7A7 other 1 1 1 -1.88200344271936 -1.74469138541299 2.52951985011346e-10 1494.08701694071 263.144309659738 5.67782377233485 3.4850795669115e-08 -340.41930871616 439.028005099409 -0.775393152058897 0.438778516937951 LARP1 other 2.82269120074161e-06 1 0.000421450672026607 5.67782377233485 -0.775393152058897 2.70658223838121e-12 227.704447639626 63.9034069132858 3.56325990488443 0.000432150422706596 -454.920453358824 106.615967840889 -4.26690731765184 2.73589114638765e-05 CNOT8 other 3.2809189893657e-08 0.41626583792288 1 3.56325990488443 -4.26690731765184 0.216278413653027 -5.01941179624944 23.6586134413427 -0.212160015577167 0.832140514408398 -64.8802776735096 39.7599950692219 -1.63179793057201 0.10387501058444 GRIA1 other 1 1 1 -0.212160015577167 -1.63179793057201 0.017230206154415 -0.291361605757892 1.56967250809884 -0.185619359614564 0.852882124343298 -11.4043106657567 4.21092616514028 -2.70826659469028 0.00719394648831963 LRGUK other 1 1 1 -0.185619359614564 -2.70826659469028 3.39043109102045e-05 26.2279873618312 8.12507152452963 3.22803156657129 0.00139980027666046 -14.8275575370232 14.8360479195498 -0.999427719391805 0.318479083782095 SETD9 other 0.264080677679583 1 1 3.22803156657129 -0.999427719391805 1.18731088385723e-14 85.951328266174 19.6468423007137 4.37481641836418 1.73552233029042e-05 -132.801413730202 35.8743295934371 -3.70185074495432 0.000259259890255262 MIER3 other 1.55454614023428e-10 1 0.174697677767033 4.37481641836418 -3.70185074495432 2.41391954715871e-19 675.932854708771 82.2057892682819 8.22244833028531 8.2574435282223e-15 -448.986580566379 224.00321823079 -2.00437558046058 0.0460210176344216 NUP205 essential 3.49607968014996e-15 1 1.20467843633235e-10 8.22244833028531 -2.00437558046058 3.61663811853964e-09 58.2536916835011 12.3658367138329 4.71085726195433 3.9651157046105e-06 -37.293454517711 24.0433854577095 -1.55108999035545 0.122060187122097 ZKSCAN2 other 3.78047182530949e-05 1 0.0420778078573266 4.71085726195433 -1.55108999035545 1.18759358856104e-19 42.9619782914018 7.43300848136005 5.77989092830159 2.07274241500525e-08 -64.9240166589543 14.0197991553403 -4.63088065239681 5.68321112671665e-06 C9orf85 other 1.72747363392089e-15 0.0878340279634059 0.000253309850537792 5.77989092830159 -4.63088065239681 0.85022522948568 -34.1176658564775 68.154641164015 -0.500591966647919 0.617063123755966 -1.58332477987172 107.109045291454 -0.0147823629233492 0.988216647214583 PIK3AP1 other 1 1 1 -0.500591966647919 -0.0147823629233492 0.000591727532086348 12.8464631089391 5.36863861851783 2.39287164247344 0.0174058305210456 -32.8850270592774 15.1848030915758 -2.16565383567742 0.0312197748790019 RBM45 other 1 1 1 2.39287164247344 -2.16565383567742 0.000149591154573885 50.46191707719 16.2023996837742 3.11447181047661 0.00204735960475489 -111.076480568738 57.9205292920153 -1.91773939096324 0.0562311817534484 TTN other 1 1 1 3.11447181047661 -1.91773939096324 6.58172988456998e-09 2036.9274155414 446.782073778098 4.5591073032914 7.7954020779372e-06 -2623.62172280352 1159.65990555057 -2.26240616774441 0.0244672442537815 PDIA4 other 6.78115630007245e-05 1 0.0807213885170397 4.5591073032914 -2.26240616774441 2.52711231300408e-43 50.0375267558089 3.04065691369628 16.4561567371908 1.72389930068322e-42 14.4435959807154 9.51220433172591 1.51842785089697 0.130089748322151 KDM8 other 4.01709773275129e-39 1 2.74099988808632e-38 16.4561567371908 1.51842785089697 7.94493765516667e-19 154.639480231502 16.7275507738489 9.24459786864067 7.77506642421206e-18 -26.3266987432828 38.6798793570046 -0.680630322041459 0.496695233162454 KCTD18 other 1.14129029416469e-14 1 1.17286877009239e-13 9.24459786864067 -0.680630322041459 5.59542407950629e-08 88.197425772082 19.0342126561245 4.6336261638699 5.65928200044416e-06 -82.5500875461015 42.5491806266982 -1.94010992292303 0.0534352168628213 FAM126B other 0.000544322854454372 1 0.0592866382366531 4.6336261638699 -1.94010992292303 0.153801122238625 7.74469902675656 4.02388226069268 1.92468330955175 0.0553235744205698 3.06898129786131 9.19441919413874 0.333787402233925 0.7388000417017 C2CD6 other 1 1 1 1.92468330955175 0.333787402233925 8.36000752896889e-21 492.827167297191 47.4785862641967 10.3799882446969 1.89669413689642e-21 171.878559660738 108.486778831087 1.58432724717867 0.114294154371025 TMEM237 other 1.2347731120287e-16 1 2.92299533437108e-17 10.3799882446969 1.58432724717867 1.89550197342481e-09 938.389368553872 143.493242908473 6.53960667090381 3.0909777871312e-10 408.479746162058 326.291955125923 1.25188420904959 0.211699500164416 FZD7 other 2.01889915189476e-05 1 4.06494488785624e-06 6.53960667090381 1.25188420904959 7.96172742156525e-05 32.3285831598442 24.368987513255 1.32662808178878 0.185795752124872 -115.749420396402 43.4902718194073 -2.66150142443463 0.00826370221259685 SPAG17 other 0.596890704794747 1 1 1.32662808178878 -2.66150142443463 0.0334671755804988 62.3541271885363 23.850086164413 2.61441936765729 0.00943806415766864 61.5691755486753 101.301458223347 0.607781730179331 0.543841225006287 DEPTOR other 1 1 1 2.61441936765729 0.607781730179331 0.0326283918671671 10.0628113604849 4.15271866612334 2.42318639174244 0.0160428972397607 -8.97881574482668 11.4029719681324 -0.787410139209282 0.431732477630288 FMN2 other 1 1 1 2.42318639174244 -0.787410139209282 8.07008173238574e-21 349.862793953723 42.9781079085707 8.14048851796831 1.45849916403084e-14 -196.270784706353 82.6235008268913 -2.3754837636034 0.0182243924998297 RNF20 essential 1.19219317432534e-16 1 2.12007438483523e-10 8.14048851796831 -2.3754837636034 0.0432475108401594 12.1887614071887 26.2799565737647 0.46380447292507 0.643157427255169 -86.3153848792876 43.8554712604232 -1.96817825458375 0.0500593519908425 PPARGC1B other 1 1 1 0.46380447292507 -1.96817825458375 0.00873111836589021 97.9287294382285 46.6102362751106 2.10101336668232 0.0365566647563559 -171.323233712853 120.759898160621 -1.41870965711629 0.157124292679388 ELMO1 other 1 1 1 2.10101336668232 -1.41870965711629 0.0548940425153141 12.6375773140289 139.76917838772 0.090417483023133 0.928021766628493 -488.248025694562 233.244037853352 -2.09329263113486 0.0372458259280855 SLC26A2 other 1 1 1 0.090417483023133 -2.09329263113486 3.12027532063839e-09 41.0092019083041 7.9206959741236 5.17747456060408 4.37914634251153e-07 -12.0609767930785 12.9250389138994 -0.933148199662925 0.351571048177223 LSM11 essential 3.27628908667031e-05 1 0.0049755860743616 5.17747456060408 -0.933148199662925 5.24180471895e-20 39.9503436565051 8.46935057564009 4.71704923532296 3.82976260659831e-06 -78.7030241772458 13.8203367637421 -5.69472549928917 3.20047940654782e-08 MED7 essential 7.662994318633e-16 0.000507500019496288 0.0406797384072873 4.71704923532296 -5.69472549928917 3.39608609436157e-37 557.93520088463 40.1320309827832 13.9024910332594 2.26727499696953e-33 -313.761813490601 141.588199609393 -2.21601669034702 0.0275401455494032 RRAGA other 5.37770233042154e-33 1 3.58909632020277e-29 13.9024910332594 -2.21601669034702 0.0994567442886746 6.65808736886459 4.06159728833071 1.63927807121445 0.102355523169091 26.3271369093104 14.4977489737414 1.81594652776749 0.0705215130187209 SLC24A2 other 1 1 1 1.63927807121445 1.81594652776749 0.000577669066624728 88.0705582355393 23.1279049344685 3.80797821873974 0.000173464227977942 -61.2292158892327 123.040306357877 -0.497635431036237 0.619146061960148 PXYLP1 other 1 1 1 3.80797821873974 -0.497635431036237 0.38987158947283 -36.4519962611832 27.7930114042105 -1.31155259611993 0.19079780248927 28.7405014534139 119.860139451184 0.239783647716506 0.810681963730914 ADCY8 other 1 1 1 -1.31155259611993 0.239783647716506 3.83319956786208e-09 71.517458733978 12.2908664140739 5.81874835545244 1.68715993573155e-08 -141.060620445934 65.1418004825579 -2.16543938609287 0.0312363542600347 RASA2 other 4.00071038897766e-05 1 0.000207250726505264 5.81874835545244 -2.16543938609287 1.71591392762644e-18 135.763831424712 16.0111956272347 8.47930626703358 1.46263911854408e-15 -52.9279443695388 30.3843721419412 -1.74194629141207 0.0826482415082646 RMND1 other 2.45375691650581e-14 1 2.15446742161543e-11 8.47930626703358 -1.74194629141207 0.0574314883721039 31.0016816639623 33.3402231970881 0.92985825201884 0.353268978474546 -110.537265476717 62.4652608538099 -1.76957982670419 0.0779175683179136 RAET1L other 1 1 1 0.92985825201884 -1.76957982670419 0.782414633302683 -21.3961275234005 32.3872105996381 -0.660635081788721 0.509409614338282 17.9710042789699 138.199191017076 0.130036971611139 0.896634001287671 SLA other 1 1 1 -0.660635081788721 0.130036971611139 3.44358259650622e-05 168.544333814779 38.2996641709985 4.40067393443113 1.55327892848459e-05 -27.8449473427125 134.386683111012 -0.207200197951985 0.836009118884969 TMBIM4 other 0.267979597660114 1 0.157020966880507 4.40067393443113 -0.207200197951985 0.251368310949964 8.93180730836869 10.3994585811487 0.858872338273416 0.391169994101215 -10.8070648425917 17.4914036999683 -0.617850060976596 0.537193036826935 MICU3 other 1 1 1 0.858872338273416 -0.617850060976596 3.93588969279114e-18 124.196960959893 13.4841058581361 9.21061895141933 9.54383666019772e-18 -22.8949875737216 47.3015734319397 -0.484021691300909 0.62876428397148 GRIP1 other 5.58856977479414e-14 1 1.43806530795859e-13 9.21061895141933 -0.484021691300909 1.28969289051234e-29 158.018167476985 32.1988079175465 4.90757818990168 1.59381625005023e-06 -363.529317954553 54.1568912985981 -6.71252188295312 1.11662332019659e-10 VPS37A essential 2.0175955579175e-25 1.78000923472538e-06 0.0174347559592995 4.90757818990168 -6.71252188295312 0.794329844815951 14.6407690909917 23.9565972549869 0.611137255227015 0.541617233014765 -4.83712181438238 64.1600587505379 -0.0753914804409656 0.939958453724865 KIF5A other 1 1 1 0.611137255227015 -0.0753914804409656 7.71134556335388e-07 274.698922949106 89.378245866479 3.07344276323654 0.00233099947564356 -257.950854710053 150.993782428335 -1.70835414916825 0.0887114753722565 PSD3 other 0.00692864398867346 1 1 3.07344276323654 -1.70835414916825 3.54799170797499e-21 121.054490574031 19.9613824335707 6.06443421325585 4.39632959922865e-09 -180.365253050015 37.694924573263 -4.78486838989322 2.80506557592409e-06 CARNMT1 other 5.2638004979517e-17 0.0436159646400437 5.54069419390786e-05 6.06443421325585 -4.78486838989322 5.12960715044895e-09 116.884223713369 35.9143201581961 3.2545297585619 0.00128057106482165 -128.376780005171 56.1879622621883 -2.28477372797629 0.0231020161328148 MCU other 5.31837669358548e-05 1 1 3.2545297585619 -2.28477372797629 5.18619127491181e-09 196.226017870244 45.6950872439235 4.29424758120663 2.43843585477703e-05 -201.93744354589 89.2905736588042 -2.26157628147323 0.024510438729404 ELMSAN1 other 5.37548725644609e-05 1 0.242575598833219 4.29424758120663 -2.26157628147323 0.00778573016262795 5.48185247145128 14.085802102423 0.389175741046959 0.697452903586159 -50.1994368187534 22.3100635436972 -2.25008040521405 0.0252491984730228 CFAP70 other 1 1 1 0.389175741046959 -2.25008040521405 0.649545757337489 -9.03377938219186 12.0357294720748 -0.750580129202133 0.453556583456156 -18.790035288241 22.4747208044287 -0.836052000456368 0.403862197504663 GNA14 other 1 1 1 -0.750580129202133 -0.836052000456368 1.20603208018239e-13 158.271418636111 22.8873563460842 6.91523373179749 3.30844017701423e-11 -30.7133339835718 44.7230829600198 -0.686744561215245 0.492826617706288 FAM161B other 1.53359039315992e-09 1 4.48425981592508e-07 6.91523373179749 -0.686744561215245 1.15785812536988e-05 121.923887602898 82.297621527832 1.48149952986995 0.139635287500338 -523.491277393125 153.677105405038 -3.40643634595661 0.000757989666751189 GNAQ other 0.0942959657301228 1 1 1.48149952986995 -3.40643634595661 0.794265981743854 267.253994668785 413.965932087746 0.645594175638919 0.519090472485119 481.047705560899 1232.48137097762 0.390308297462807 0.696616337040399 WIF1 other 1 1 1 0.645594175638919 0.390308297462807 0.14517500131496 20.3138890437084 10.5407422592983 1.92717823318267 0.0550144116800598 6.45197200196294 36.0294993412893 0.179074706002619 0.858014348348045 MMP16 other 1 1 1 1.92717823318267 0.179074706002619 1.05600410138318e-12 375.724197427529 73.1261168900561 5.13803020598542 5.36583473474941e-07 -178.786796386606 114.672377242336 -1.55910953174693 0.120154945352634 ADK other 1.30036345044325e-08 1 0.00605588108163819 5.13803020598542 -1.55910953174693 0.846683276498602 5.19540169584852 66.805666052215 0.0777688780437849 0.938069291014398 51.6398117670984 102.740208316958 0.502625141734064 0.615636047356513 KCNMA1 other 1 1 1 0.0777688780437849 0.502625141734064 0.295829843416793 -22.9384873762976 16.2518444614463 -1.41143901731978 0.159266506786689 -37.998810619245 30.4576778209703 -1.24759381994259 0.21326081622692 BATF other 1 1 1 -1.41143901731978 -1.24759381994259 2.12393583653246e-16 296.669996904379 43.3927360761725 6.83685850976529 5.35259300137945e-11 -173.167013702201 94.0979058970535 -1.8402855201863 0.0668197062231214 DCK other 2.90809294738024e-12 1 7.2152953658595e-07 6.83685850976529 -1.8402855201863 0.00640106957964916 9.25524332686834 7.26892314791443 1.27326195896346 0.204020235071812 -30.4131582705035 15.6893251845224 -1.93846184668964 0.0536090723621798 ADAMTS3 other 1 1 1 1.27326195896346 -1.93846184668964 5.26800315606455e-07 76.8327955307315 18.5309514770681 4.14618729242325 4.51649803245658e-05 -6.68048842787059 27.5277780583741 -0.242681716399496 0.808434198057924 ALX3 other 0.00480231167706845 1 0.438190639108938 4.14618729242325 -0.242681716399496 4.12197847555797e-09 176.439829434776 29.8210470069821 5.91662088167011 9.96398197940998e-09 -86.5665053856933 107.410097397466 -0.805943831010207 0.420987118013271 DPY19L4 other 4.29386497798874e-05 1 0.000123722764238334 5.91662088167011 -0.805943831010207 3.58201206656722e-11 71.6814946067695 10.8676088007313 6.59588469930442 2.24463110238814e-10 -41.8498854639598 39.0472446248396 -1.07177563656662 0.284785014657554 NDUFAF6 other 4.15370119239134e-07 1 2.96628000180593e-06 6.59588469930442 -1.07177563656662 1.0478247397996e-07 44.1046684164353 62.9190091307246 0.700975254152535 0.483915498043186 -375.815111791443 92.4593534030392 -4.06465217373119 6.2956729766238e-05 DRAM2 other 0.00100276827598822 0.946428518575856 1 0.700975254152535 -4.06465217373119 2.62866714977704e-11 27.3597538106317 4.02335433486237 6.80023471300039 6.7362865579924e-11 -9.70026546961161 14.4790074790829 -0.669953757785199 0.503461955942339 C8orf37 other 3.06555163006998e-07 1 9.05222187663019e-07 6.80023471300039 -0.669953757785199 0.559174583312097 -14.0445836080753 40.1619803589204 -0.349698483056896 0.726838612463766 -84.5155059694999 78.3137484569915 -1.07919117185298 0.281469212492676 ADAMTSL3 other 1 1 1 -0.349698483056896 -1.07919117185298 0.000696027403075383 52.0870667439698 13.4770278089657 3.86487788570997 0.000139273444425727 51.2315262047084 26.5629281009293 1.92868519652832 0.0548181833242827 ART3 other 1 1 1 3.86487788570997 1.92868519652832 3.12255772736485e-07 65.2881783625289 14.2685472258643 4.57567104268207 7.24436712613533e-06 -40.9868151300098 27.7891577608458 -1.47492109990319 0.141398850435261 WHAMM other 0.00289773357099458 1 0.0752979519090506 4.57567104268207 -1.47492109990319 0.172808210217021 -187.950458403042 1437.74565096413 -0.130725805553302 0.896089205333645 -3632.48028290917 2286.67213746317 -1.5885444281221 0.113329251687649 CXCL13 other 1 1 1 -0.130725805553302 -1.5885444281221 4.8981288418289e-07 35.8876901699879 11.2584381023936 3.18762601380364 0.00161205427979618 -38.7115240714211 16.1625065214701 -2.39514360102482 0.0173302567223349 N6AMT1 other 0.0044773795743158 1 1 3.18762601380364 -2.39514360102482 8.87251982760639e-11 98.9647048692127 23.9528215734019 4.13165123640828 4.87637434505189e-05 -104.279577375459 34.3864425390776 -3.03257823943124 0.00267290179125324 RWDD2B other 1.01155598554541e-06 1 0.471057761732013 4.13165123640828 -3.03257823943124 6.25296593731915e-15 223.509736447352 40.555507405704 5.5112055241088 8.65692123787972e-08 -179.889871604346 58.2211002063301 -3.0897710789874 0.00222319675729404 USP16 other 8.25078855429261e-11 1 0.00102679742802491 5.5112055241088 -3.0897710789874 8.82738455525683e-20 1312.1381763232 172.015284999148 7.62803245263757 4.6420275530258e-13 -543.448779060095 246.943504978741 -2.20070084089427 0.0286469523458726 CCT8 essential 1.28641475123758e-15 1 6.59028651703073e-09 7.62803245263757 -2.20070084089427 0.507076978182499 -4.95860104248016 14.680713325913 -0.337762950096417 0.735817554385185 -24.0098359472918 21.0754922407449 -1.13923013863819 0.255667906434047 MAP3K7CL other 1 1 1 -0.337762950096417 -1.13923013863819 0.343286474800501 14.9523733112805 10.8266817198308 1.38106704327447 0.168400321206238 7.35338813766153 16.8851239914583 0.435495063073355 0.663551059296533 NAA11 other 1 1 1 1.38106704327447 0.435495063073355 0.000493394099258816 309.09182633312 80.3012276512347 3.84915443230297 0.000149375893241003 124.651098973225 115.212966722191 1.08191901067692 0.280294808568523 CLDN8 other 1 1 1 3.84915443230297 1.08191901067692 1.98701512880208e-06 128.523668523912 64.8311833986597 1.98243594804671 0.0484671141941744 -300.805833565759 93.3928336572435 -3.22086633188293 0.00143820582899287 TIAM1 other 0.0172810705751917 1 1 1.98243594804671 -3.22086633188293 6.83344559591427e-13 250.72505653919 54.8658961547635 4.56977966480224 7.49230770287276e-06 -262.093414323691 78.6447952890628 -3.33262250045097 0.000982902004293759 SCAF4 other 8.47825595085084e-09 1 0.0777102154941963 4.56977966480224 -3.33262250045097 0.000580266330791721 70.7491359798943 18.1854267486882 3.89043034060214 0.000125783214814393 47.3875241880034 34.246427127737 1.38372169485742 0.167573998808984 CDK20 other 1 1 1 3.89043034060214 1.38372169485742 1.76894388321396e-16 76.8005152431854 11.1608601002271 6.88123626257284 4.08186836392994e-11 -17.5574279824949 16.9262434474438 -1.03729029048949 0.300521844191195 PCGF6 other 2.4257527470513e-12 1 5.51819834629756e-07 6.88123626257284 -1.03729029048949 1.01225653971405e-05 119.571078340345 34.9747035100059 3.41878747610075 0.000726904384296677 -122.704675360735 77.5548493176182 -1.58216638212022 0.114790977021997 ANKRD9 other 0.0828633203409919 1 1 3.41878747610075 -1.58216638212022 5.51890319386527e-05 73.7446434425008 21.1689205384875 3.48362795865876 0.000576617966706544 -12.4531692344369 32.1581559070168 -0.387247616761497 0.698876844434454 SFR1 other 0.420926746596104 1 1 3.48362795865876 -0.387247616761497 5.83256084914107e-11 56.7225691108974 20.267439701082 2.79870422448422 0.00549785423145908 -119.283995090191 30.5418927875297 -3.90558620318696 0.00011864440575743 SFXN2 other 6.7062784643424e-07 1 1 2.79870422448422 -3.90558620318696 1.0669564838329e-19 634.037451260389 68.6199050572632 9.23984739896223 8.338257555213e-18 65.6388853753305 161.355775065036 0.406796009308462 0.68448617558703 C14orf2 other 1.55274177092202e-15 1 1.25732585675057e-13 9.23984739896223 0.406796009308462 0.0352453904757714 -36.4112343768341 30.4778336986735 -1.19467921299206 0.233253081666841 -148.94627567529 57.3897398532816 -2.59534676505025 0.00996256237390542 FUT6 other 1 1 1 -1.19467921299206 -2.59534676505025 0.247867616357445 -20.3640587792099 18.1801630807765 -1.1201251984776 0.263682262798489 -69.2516867236201 42.8187240303007 -1.61732252167566 0.107007407193404 TDRD9 other 1 1 1 -1.1201251984776 -1.61732252167566 0.162046281305381 9.57758325410461 5.60442196393302 1.7089332879895 0.0886039700558527 0.615741051964253 9.08248659294551 0.0677943254485514 0.945999168743162 FGF18 other 1 1 1 1.7089332879895 0.0677943254485514 2.5448818559281e-05 40.6383452436524 102.554392750954 0.396261380459244 0.692221754492337 -680.003234938532 170.172168063502 -3.99597209506539 8.29429335852271e-05 PCDH1 other 0.200918422525523 1 1 0.396261380459244 -3.99597209506539 0.0472628327734125 5.42140628567109 76.9552420509246 0.0704488237732202 0.94388819936534 -277.381219085305 128.556666855061 -2.15765720962597 0.0318300546569143 SH3RF2 other 1 1 1 0.0704488237732202 -2.15765720962597 0.36217648804466 3.9814323607427 3.70943003690403 1.07332725543617 0.28408620371093 -8.32863616268787 13.4923745481865 -0.61728468424465 0.537569118843373 GDF6 other 1 1 1 1.07332725543617 -0.61728468424465 4.69274513258337e-07 420.202584159685 76.9382958207097 5.46155304945782 1.06803305044473e-07 153.948735817168 280.720726530731 0.548405305585139 0.583865114451829 UQCRB essential 0.00429620816888007 1 0.00126070621274496 5.46155304945782 0.548405305585139 2.15248696492316e-07 93.5535663344958 18.2180678243703 5.13520792854603 5.39017033249728e-07 -65.9124948966626 66.4713090027498 -0.991593153279649 0.32228056131222 MTERF3 other 0.00201817177831196 1 0.00608226820318993 5.13520792854603 -0.991593153279649 0.875543138350228 73.2332582744462 237.947614772749 0.307770507993482 0.75849336921812 -273.283812250529 868.186987802772 -0.314775291601827 0.753174492733538 PTDSS1 other 1 1 1 0.307770507993482 -0.314775291601827 0.49057061330381 11.5684247769914 25.6580589091273 0.450869055136363 0.652443138461878 -33.3449258903741 43.1378496476038 -0.772985351907228 0.440202247883049 PPP2R2B other 1 1 1 0.450869055136363 -0.772985351907228 2.08077219314023e-08 3000.68125957158 492.831657701623 6.08865362579506 3.89715713638979e-09 1498.84622073521 1793.75874468294 0.835589638337982 0.404124614121582 RPL30 essential 0.000207931565260503 1 4.9260066203967e-05 6.08865362579506 0.835589638337982 4.5578724943358e-24 239.99616311789 30.4480893995758 7.88214196195947 7.79968144841959e-14 -84.5783504623999 47.6408896366888 -1.77533104665756 0.0769614125786193 SUPV3L1 essential 6.94163980887343e-20 1 1.12073622732341e-09 7.88214196195947 -1.77533104665756 4.9534160238337e-06 17801.4419364699 3527.28523229835 5.04678265694738 8.33890209131172e-07 10240.1120544875 8085.638673447 1.2664567968039 0.20645747244888 EEF1A1 essential 0.0416285082642984 1 0.00929704194160343 5.04678265694738 1.2664567968039 0.0504263824303114 5.26791432280398 2.77603178448012 1.8976419334444 0.0588139178193261 -11.093783354969 10.8683766929821 -1.02073968066753 0.308294900577646 FBXO43 other 1 1 1 1.8976419334444 -1.02073968066753 0.443256177196323 -14.3867568659904 28.1123142825227 -0.511759961183083 0.609234237878571 -54.5329233947279 44.0597933880205 -1.23770265816896 0.21689365917072 HKDC1 other 1 1 1 -0.511759961183083 -1.23770265816896 5.39690705964749e-07 1791.19607168006 430.68962549803 4.15890229445114 4.29095392916955e-05 -186.252486659727 676.998478378774 -0.275115074269814 0.783436695004878 HK1 other 0.00491388387780904 1 0.41733817915103 4.15890229445114 -0.275115074269814 9.85535309392591e-13 350.632881189737 74.0033264108455 4.73806919493216 3.48056510089777e-06 -220.133250531133 115.812969983708 -1.90076509187271 0.0583898318968772 TYSND1 other 1.21506648295013e-08 1 0.0370575766292586 4.73806919493216 -1.90076509187271 0.00257940791177999 -204.415272600856 212.375012393886 -0.962520356310716 0.336659174074658 -1707.74893994893 489.573254167471 -3.48823986075993 0.000568458596991819 CD109 other 1 1 1 -0.962520356310716 -3.48823986075993 0.197122356044882 -31.3627987917421 181.189576500344 -0.173093835735537 0.862706881862729 -821.001409688311 470.990756031813 -1.7431369919134 0.0824438523618983 UBE2L6 other 1 1 1 -0.173093835735537 -1.7431369919134 4.4460758655567e-08 404.862777519606 129.226029453864 3.13298163868874 0.00192022422611192 -1233.91743382728 335.914827370597 -3.67330446079405 0.000288468088458702 ZDHHC5 other 0.000435404209513967 1 1 3.13298163868874 -3.67330446079405 1.17825162334397e-08 58.2003871470499 13.8448661663711 4.20375223910921 3.56897516381694e-05 -101.278285775869 35.7419517260969 -2.83359696056892 0.00494874790726247 MED19 essential 0.000119486497123312 1 0.349652496799146 4.20375223910921 -2.83359696056892 5.69759906176729e-17 368.920936165901 54.1879864646083 6.80816838261473 6.42697323855814e-11 -356.151823584676 106.080193487033 -3.35738286175176 0.000900459500051464 ZFAND3 other 7.90940701754536e-13 1 8.64684979515612e-07 6.80816838261473 -3.35738286175176 5.66399669142886e-09 382.252896867489 126.733926323526 3.01618444213332 0.00280377686589127 -935.544975107905 237.372499390429 -3.94125257774333 0.000103308454318858 NPTN other 5.85487337993002e-05 1 1 3.01618444213332 -3.94125257774333 3.95780909695889e-07 235.265122514452 65.225254802076 3.60696364051558 0.000369455225662361 -121.043699810257 100.724486669854 -1.20173061995345 0.230528754920404 KAT6B other 0.00364435061647974 1 1 3.60696364051558 -1.20173061995345 3.51134512310573e-07 179.866264742805 54.4307930434739 3.30449465616174 0.00108112658477891 -134.35520667049 84.055075062159 -1.59841873403996 0.111128103550147 SAMD8 other 0.00324764310436049 1 1 3.30449465616174 -1.59841873403996 0.00184326724438485 604.641628053178 318.711772548896 1.89714243442456 0.0591748045587013 -1050.5644665019 659.479626908837 -1.59302035064554 0.112652538078294 RAB11FIP1 other 1 1 1 1.89714243442456 -1.59302035064554 0.807797467276336 -1.31442970592898 11.1835648421696 -0.117532264933333 0.906536988900877 -12.7043819992601 22.1702519277116 -0.573037331316039 0.567158155153541 UNC5D other 1 1 1 -0.117532264933333 -0.573037331316039 0.0199947135271241 97.2528730272145 42.2912945389401 2.29959555713453 0.0222259949130717 -62.9007315746878 101.472363172053 -0.619880424663369 0.535853553647298 GLYATL2 other 1 1 1 2.29959555713453 -0.619880424663369 1.08315153467379e-09 612.544528653138 118.475915693083 5.17020294858883 4.52678473173955e-07 -454.400798866093 231.977811230547 -1.95881147621699 0.0511527487412744 MAPK13 other 1.16785398468528e-05 1 0.00513608995663169 5.17020294858883 -1.95881147621699 1.00440368340156e-19 257.317233537671 37.1344744524929 6.92933553878252 5.54975304266608e-11 -254.095999508047 78.8773172774407 -3.22140772884425 0.00148689720468722 BAG4 other 1.46211044192765e-15 1 7.47829222499255e-07 6.92933553878252 -3.22140772884425 0.512183134726502 -89.753465165723 83.4717230215108 -1.07525592999432 0.283209535648258 4.84101368977131 196.718672569832 0.0246088163697466 0.98038496491419 MS4A1 other 1 1 1 -1.07525592999432 0.0246088163697466 3.85816634970607e-17 99.0042010189493 11.0812308003324 8.93440474283596 6.65043009919013e-17 -56.0935075627304 47.9807020881289 -1.16908475952895 0.243404401861486 TBC1D31 other 5.38021297466511e-13 1 9.94771334236859e-13 8.93440474283596 -1.16908475952895 2.44291316733795e-09 67.3779958926266 10.3175121370041 6.53044987957641 3.2585401644371e-10 35.7627982369257 43.9384847572191 0.813928801471696 0.416405636167955 WDYHV1 other 2.58386925709335e-05 1 4.28237348410324e-06 6.53044987957641 0.813928801471696 2.79023439907688e-10 338.716387579254 50.9852397882383 6.64342050730911 1.71261198128013e-10 -165.254123087484 224.19640663284 -0.737095324449672 0.461711593461055 ATAD2 other 3.10608893305238e-06 1 2.2736636663475e-06 6.64342050730911 -0.737095324449672 0.0450725488065555 163.70436404834 79.9034255450298 2.04877779559131 0.0414541227388112 -374.912904755123 345.206463535882 -1.08605412805706 0.278427315896703 FBXO32 other 1 1 1 2.04877779559131 -1.08605412805706 3.36012460450451e-10 125.438568092336 18.2379387321742 6.87789173625444 4.27318210613441e-11 68.582052067496 80.0452027636805 0.856791534028248 0.392325570684521 NSMCE2 essential 3.7250341365537e-06 1 5.77477829823004e-07 6.87789173625444 0.856791534028248 1.87671044472909e-11 55.2772791049074 11.6183139184118 4.75777117859658 3.20882938189379e-06 -62.3704749684206 23.6253749177149 -2.63997820926234 0.00877905661993248 ZNF689 other 2.20344573315643e-07 1 0.0342799242867713 4.75777117859658 -2.63997820926234 1.82602906877734e-10 156.955353288243 37.9719970728696 4.13345005233832 4.78815790408863e-05 -227.778681185142 77.2145316024949 -2.949945773909 0.00346016659090791 PRR14 other 2.0509958500507e-06 1 0.462919106167289 4.13345005233832 -2.949945773909 8.37547733298028e-11 389.419107065766 96.2551616833401 4.04569583859695 6.83494606823702e-05 -623.986684734814 195.731006969127 -3.18798076195069 0.00160329360037307 FBRS other 9.56144492333029e-07 1 0.652122204370494 4.04569583859695 -3.18798076195069 8.7505477166254e-08 1.89168770450011 39.3958361088636 0.0480174528920456 0.961737571067312 -306.829517870791 63.0899584662549 -4.86336534893909 1.95519751147583e-06 FRRS1 other 0.000840840130090535 0.0304697980188394 1 0.0480174528920456 -4.86336534893909 5.24582760904931e-12 221.507372217256 40.614533574459 5.45389427681507 1.12301491207484e-07 -161.193043920494 84.5446183144692 -1.90660324848739 0.0576454024238363 PHKG2 other 6.28135397907564e-08 1 0.00132470839028348 5.45389427681507 -1.90660324848739 7.21615163031924e-10 248.162271301156 73.8522119586857 3.36025509215598 0.00089023070017682 -355.644549067827 118.269681400828 -3.00706440446484 0.0028845530319831 MFSD14A other 7.85983235574371e-06 1 1 3.36025509215598 -3.00706440446484 4.4141005775671e-14 99.5405598835459 14.6409374075977 6.79878324128963 6.66974784997089e-11 -4.77573451780547 23.4465421777039 -0.203686090751023 0.838751116283986 SASS6 essential 5.6906584645995e-10 1 8.96747598428586e-07 6.79878324128963 -0.203686090751023 0.155529654437463 -3.31834177022807 2.14074249792643 -1.55008917393955 0.122322592483847 -7.76404363024187 4.38867817311524 -1.76910753625178 0.0780348714550684 ITGAD other 1 1 1 -1.55008917393955 -1.76910753625178 1.38646748419084e-11 257.258591295837 39.9689194116452 6.43646601115973 5.58557773103458e-10 -196.013495082795 113.131065843749 -1.7326230741388 0.0843088109563327 MALSU1 other 1.63727945208097e-07 1 7.27912489908427e-06 6.43646601115973 -1.7326230741388 7.77276962872483e-26 234.816825558547 19.5563305572298 12.0072027250397 7.27847874578697e-27 246.858397637397 208.5905020047 1.1834594349451 0.237675803245641 VPS8 other 1.19661788434219e-21 1 1.14206610000143e-22 12.0072027250397 1.1834594349451 4.72858666237129e-15 104.861026155465 14.6753915201268 7.14536481099341 8.30838594878882e-12 -36.8069856989062 28.0462036161839 -1.31236962416072 0.190505879681017 GALK2 other 6.26443161030949e-11 1 1.14564333847849e-07 7.14536481099341 -1.31236962416072 0.768450434057458 -6.7803632560248 9.36675659298459 -0.723875248461467 0.469766725290438 -4.4243430798942 25.8957785962801 -0.170851904044691 0.864467707308825 LHFPL4 other 1 1 1 -0.723875248461467 -0.170851904044691 0.0169762535370679 -95.1422107678361 80.6702577747219 -1.17939638960282 0.239267153201865 -356.609783752054 125.171051352817 -2.84897969536811 0.00471986919197965 B3GNT7 other 1 1 1 -1.17939638960282 -2.84897969536811 1.05001311081084e-05 95.1931288882085 27.3407328225221 3.48173289670541 0.000581503344094431 -59.9767213694565 53.6590986574707 -1.11773628089271 0.264680607403742 MPV17L other 0.0858280716776781 1 1 3.48173289670541 -1.11773628089271 7.81649877790956e-10 305.804455543664 53.077272175886 5.76149532572619 2.24531586602206e-08 -8.27534486859316 92.0685743113781 -0.0898824048323562 0.928446570440562 BUB1B other 8.50200572073223e-06 1 0.000273906082496032 5.76149532572619 -0.0898824048323562 5.1878283303073e-08 31.2129915870254 23.8137207877472 1.31071460294795 0.191055746596597 -156.588022918769 36.9502782047483 -4.23780362494392 3.09053733227388e-05 PDE6D other 0.000505761383921659 0.469514431519048 1 1.31071460294795 -4.23780362494392 8.39516923973711e-23 187.578893068695 17.7679495010404 10.5571491554335 4.62634863770597e-22 -1.24846649448412 49.3713338152799 -0.025287274983398 0.979844365555243 BRPF1 other 1.26523595612078e-18 1 7.14863391498327e-18 10.5571491554335 -0.025287274983398 2.12956373731924e-11 342.409779343644 47.7444151235021 7.17172424162955 7.01614256192447e-12 95.6653132983348 132.666150178989 0.721098133693232 0.471468467948179 RPUSD3 other 2.49329322365337e-07 1 9.68648642099292e-08 7.17172424162955 0.721098133693232 2.31975390199909e-15 258.970879806281 34.2987316825633 7.55045061733103 6.58696608912636e-13 -176.198624156151 96.6003837342875 -1.82399507481056 0.0692499964626252 TATDN2 other 3.09547960682759e-11 1 9.31594613985141e-09 7.55045061733103 -1.82399507481056 1.48891275923842e-34 1099.83026706231 79.0833199723802 13.9072343883189 1.40701502592251e-33 105.47924035608 226.791327872893 0.465093799420746 0.6422364077489 SEC13 essential 2.3505465730097e-30 1 2.22758618904051e-29 13.9072343883189 0.465093799420746 7.49706643189317e-19 54.53359375 6.25299104950703 8.72120131281802 2.74971977051742e-16 -27.3596191406247 19.5288691520722 -1.40098327904059 0.162354753775281 EXOG other 1.07815312357056e-14 1 4.08910827073645e-12 8.72120131281802 -1.40098327904059 1.60816767405792e-07 33.8638145788412 22.0471819834314 1.53597020264495 0.125721027716555 -170.385779304963 43.2349917085986 -3.94092314052823 0.000103532633394492 NTAN1 other 0.00151811028431068 1 1 1.53597020264495 -3.94092314052823 0.181842010607386 16.633828620436 9.01057367842427 1.84603436074948 0.0659777286914374 -1.02055915031881 27.7418049857747 -0.0367877703286476 0.970681308904326 NMNAT2 other 1 1 1 1.84603436074948 -0.0367877703286476 3.4620707776817e-06 188.746383243708 39.31975013086 4.80029457500472 2.63148181585418e-06 75.3110331252341 63.2808112255791 1.19010852842532 0.235052997711767 ZFYVE9 other 0.0294518361057382 1 0.0283173758204068 4.80029457500472 1.19010852842532 0.110588185279321 -6.68189910979233 3.26016111590585 -2.0495610100962 0.0413662653839134 -10.3537091988131 9.34933268879058 -1.1074276147245 0.269087450414584 SLC6A1 other 1 1 1 -2.0495610100962 -1.1074276147245 7.18197005819465e-12 641.870374360515 111.166430076535 5.77395868445724 2.12386121145422e-08 -254.912582876588 217.528627666176 -1.1718576336894 0.242287229636069 SMG1 essential 8.5637810973913e-08 1 0.000259344692530674 5.77395868445724 -1.1718576336894 3.41945610125298e-05 9.67615678587553 51.1207406465614 0.189280449842747 0.850014179428595 -312.279213897084 79.5856362716165 -3.92381374989968 0.000110458683779045 FCHO2 other 0.26613626836052 1 1 0.189280449842747 -3.92381374989968 4.17904709043211e-05 -106.26776904209 79.5037837220691 -1.3366378814571 0.182461935498378 -588.258573253873 138.321741136878 -4.25282799666147 2.90884830208586e-05 RBPMS other 0.322580644910455 0.442290384332155 1 -1.3366378814571 -4.25282799666147 0.172860857168229 4.58121105951994 11.1846685644204 0.409597390672197 0.682423688978731 -24.2676592490527 17.4124817623592 -1.393693304622 0.164547883145629 TMEM171 other 1 1 1 0.409597390672197 -1.393693304622 0.620208375159279 3.70847506006043 4.88507994199269 0.759143167378278 0.448421881268064 -4.90330867486486 14.2094653057402 -0.345073411937892 0.730304893888156 TIMP4 other 1 1 1 0.759143167378278 -0.345073411937892 0.770425843721657 19.8668680573725 36.7948053622909 0.539936761772711 0.589680797677727 67.0421166242476 107.026807429003 0.626404900180927 0.531572812040551 SYN2 other 1 1 1 0.539936761772711 0.626404900180927 0.000699442943208738 151.193400687298 56.2634102939878 2.68724202634148 0.0076619967953273 -52.5590567617604 102.663154680778 -0.511956377389611 0.609109526759274 NRG1 other 1 1 1 2.68724202634148 -0.511956377389611 1.38969087019707e-08 111.421411010197 18.4466194577995 6.04020759820502 5.25373005957621e-09 -78.0388023835652 57.2012138225778 -1.36428577592112 0.173648371093561 C1orf27 other 0.00014026149952899 1 6.60341331188134e-05 6.04020759820502 -1.36428577592112 2.25220045378192e-24 174.710564740314 21.0584004089144 8.2964784289293 5.02964682720733e-15 -92.9687451093649 37.2804726733779 -2.49376519240739 0.013233931989093 CPT2 other 3.43663267242583e-20 1 7.36239702566608e-11 8.2964784289293 -2.49376519240739 1.44565219484979e-14 186.423193688914 83.4722583746716 2.23335509687709 0.0263359486881677 -726.965893957523 128.061761413452 -5.67668198480019 3.50593639426319e-08 NECAP2 other 1.88672067949846e-10 0.000555620799762831 1 2.23335509687709 -5.67668198480019 0.0330845178584417 252.157342527593 96.9186366630791 2.60174256685197 0.00978319349142013 181.446960102096 171.578681927305 1.05751459367762 0.29121508420013 LRP8 other 1 1 1 2.60174256685197 1.05751459367762 6.53377664345595e-16 140.278932613822 19.8980641582403 7.04987839511656 1.54120851057038e-11 -84.51610733271 50.2473568463501 -1.6820010571133 0.0937421567075999 PAXIP1 other 8.84085317626024e-12 1 2.10960620926874e-07 7.04987839511656 -1.6820010571133 0.000268722245645749 122.694251346937 30.4443823296296 4.03011136893804 7.29039328814212e-05 -2.81182248664715 127.498970249061 -0.0220536878153167 0.982421725694238 STEAP2 other 1 1 0.694118344964012 4.03011136893804 -0.0220536878153167 1.60679627969214e-09 389.068701514878 112.032082487387 3.47283289640431 0.000598949532822058 -580.940556090516 198.457193323101 -2.9272839465421 0.00370844592580866 SSBP3 essential 1.71718318410699e-05 1 1 3.47283289640431 -2.9272839465421 6.63576913006751e-10 252.542469664525 39.2433479784779 6.43529369112508 5.77185197916595e-10 -141.906763026409 166.794915752415 -0.850785903073034 0.395659284357702 CLDN12 other 7.24493273620771e-06 1 7.5195687584574e-06 6.43529369112508 -0.850785903073034 6.847691524307e-05 3082.14359759792 769.527052042623 4.0052439864417 8.0002032318812e-05 764.704311267447 1454.59774804265 0.525715313595428 0.599514346308561 MMP14 other 0.517617002322366 1 0.758339264350019 4.0052439864417 0.525715313595428 1.19110802799717e-13 842.807627544236 103.688980481532 8.12822754771271 1.61907017335292e-14 292.445022225884 468.574706269853 0.624116108515395 0.533082230121389 FZD1 other 1.5149703008096e-09 1 2.35202324082979e-10 8.12822754771271 0.624116108515395 1.53304392871643e-77 420.276075749787 15.6048112604946 26.9324677328053 3.25873202200649e-78 -82.7887471990371 143.155612703278 -0.578312967516233 0.563538480604253 GATAD1 other 2.44765793658865e-73 1 5.20354329273996e-74 26.9324677328053 -0.578312967516233 0.00541961535937685 15.222819461866 5.86192515366165 2.59689761687882 0.00992652400123366 -7.95207630337617 11.735870171015 -0.677587276230784 0.498617942865952 SUSD3 other 1 1 1 2.59689761687882 -0.677587276230784 5.5082798491237e-15 165.800604425407 28.2696382591074 5.86497085338515 1.29519519767257e-08 -130.261768983612 57.4177130670267 -2.26866870910637 0.0240693730784697 ZFHX2-AS1 other 7.27974264860188e-11 1 0.0001600472705764 5.86497085338515 -2.26866870910637 0.530095828518658 0.940748441529551 2.74366780849725 0.342879862720995 0.731952708277145 -3.62141942542486 4.95844011247435 -0.730354575890543 0.465799757728912 CLEC18A other 1 1 1 0.342879862720995 -0.730354575890543 0.408131137969804 1.01970781309175 2.31194622817843 0.441060350220676 0.659518396426933 -3.51433432121624 4.17821971019243 -0.841108071134532 0.401023512491382 CLEC18C other 1 1 1 0.441060350220676 -0.841108071134532 1.82567225206252e-18 169.47391703587 29.2833218828738 5.78738702233731 1.95785251348228e-08 -190.731762739782 52.9217120967962 -3.60403613531863 0.000372284168577933 DDX19B other 2.60961591709816e-14 1 0.000239582412074826 5.78738702233731 -3.60403613531863 0.000334722465726806 83.6628496414166 34.7772894008859 2.40567482637924 0.0168078989644767 -94.3932214801408 62.8505776954572 -1.50186720538232 0.134287163804597 ST3GAL2 other 1 1 1 2.40567482637924 -1.50186720538232 6.7468593172868e-12 64.7865336901806 20.4865728953818 3.16239002106522 0.00174202413780927 -152.469929880471 37.0619563165959 -4.11392017674459 5.15925442092323e-05 FUK other 8.04967785145488e-08 0.778531492117316 1 3.16239002106522 -4.11392017674459 0.0180696496855219 -43.3152407062449 20.2984302860246 -2.13392070696557 0.033743789787473 -97.0671101841941 35.3580660930532 -2.74526072576308 0.00644914950490846 IL34 other 1 1 1 -2.13392070696557 -2.74526072576308 3.63176956611586e-05 69.8629159765092 33.4218826841728 2.09033454628196 0.0375162084192332 -154.745875370176 65.4980243415205 -2.36260371096535 0.0188512424230935 DHRS1 other 0.282079542200219 1 1 2.09033454628196 -2.36260371096535 0.509774245909624 -40.1215136650316 39.5987069368841 -1.01320262121137 0.311863817119566 -82.5024106517173 95.1003349418477 -0.867530179595752 0.386416289497124 CACNA1D other 1 1 1 -1.01320262121137 -0.867530179595752 0.726576573217088 40.2209166696213 160.895123401792 0.249982198460922 0.802808063884042 -208.178088143992 356.595572447469 -0.583793249913833 0.559890004676928 KIT other 1 1 1 0.249982198460922 -0.583793249913833 0.467819542529063 -16.9601515715634 20.139801313303 -0.84212109681344 0.400473836053559 -42.58913876314 35.0401672731394 -1.21543765562407 0.22527283464968 HYDIN other 1 1 1 -0.84212109681344 -1.21543765562407 5.37211626133264e-42 120.44856565221 9.12929045387293 13.1936393371198 1.00662556723233e-30 -72.0057571513974 20.1125030673695 -3.58014897052866 0.000410205055928981 AASDH other 8.53145783462237e-38 1 1.5896630957733e-26 13.1936393371198 -3.58014897052866 5.1480865782027e-09 11.850586237271 3.78073679898133 3.13446475313065 0.00191088569183662 -19.3554280332857 6.55021818127072 -2.95492875162989 0.00340232255177919 ZNF19 other 5.33702135562274e-05 1 1 3.13446475313065 -2.95492875162989 0.203549276504832 51.7967335856507 29.4394972565269 1.75942996357274 0.0796328771355794 17.0526575612964 74.1043358385275 0.230116866554933 0.818174563283751 CACNA2D3 other 1 1 1 1.75942996357274 0.230116866554933 3.17505663742795e-17 137.477706314939 21.2467562712522 6.47052682112009 4.52652084029079e-10 -149.906396636578 41.4791030167674 -3.6140221396779 0.000359083581305354 RNF111 other 4.43618913381433e-13 1 5.92023660701632e-06 6.47052682112009 -3.6140221396779 1.27632567910649e-11 398.79063005457 58.5124496709213 6.81548341075105 6.04026722271379e-11 3.54104266233564 114.231268843021 0.0309988910934869 0.975293157465996 CCNB2 other 1.50861695270387e-07 1 8.13261578866185e-07 6.81548341075105 0.0309988910934869 0.0039974956565718 20.1515839514576 6.85305875921561 2.9405240286841 0.00355830567756085 -4.13398163176774 13.3789236636596 -0.308992093511725 0.757564085927116 FAM81A other 1 1 1 2.9405240286841 -0.308992093511725 0.00166691690840171 216.78007279474 76.7459715042734 2.82464432393913 0.00508237257705428 -141.826985092382 150.882033378851 -0.939985907641283 0.348055739097119 MYO1E other 1 1 1 2.82464432393913 -0.939985907641283 1.32781177295865e-07 273.436613113914 56.009892610299 4.88193425072975 1.78994208193579e-06 -187.48028893925 133.441496367245 -1.40496242955253 0.16116928963906 APPL1 other 0.00126102284077883 1 0.0194960491564446 4.88193425072975 -1.40496242955253 0.00179161963207579 123.246347034176 37.8069879170784 3.25988273132181 0.00125592614759809 11.8373150095465 62.6353635120843 0.18898772747224 0.850242856255483 AFAP1L1 other 1 1 1 3.25988273132181 0.18898772747224 1.0900877865745e-20 255.003039321267 35.5333339251939 7.17644563997595 6.81551136582541e-12 -186.852075163221 56.6212850365107 -3.30003240023136 0.00109577547454181 DSCR3 other 1.60744345008276e-16 1 9.4115396450683e-08 7.17644563997595 -3.30003240023136 1.78355789698263e-16 314.636958584265 67.0885208209573 4.68987771281996 4.33145155533987e-06 -498.522143514734 106.903513981501 -4.66329052196545 4.88329951654561e-06 DYRK1A other 2.44561458834258e-12 0.0756032431151591 0.0458224260039404 4.68987771281996 -4.66329052196545 0.196678843901104 9.62675596286795 11.6097472868039 0.829195995834473 0.407720586193006 -18.850920506528 18.5942814316019 -1.01380204316419 0.311578173626369 KCNJ6 other 1 1 1 0.829195995834473 -1.01380204316419 0.148843599415932 119.890684392862 113.855543273264 1.05300700296263 0.293272310409984 -172.357089958309 182.352118601008 -0.945188305354608 0.345401606594973 KCNJ15 other 1 1 1 1.05300700296263 -0.945188305354608 0.976693150434357 9.51383254389705 49.7210600349372 0.191344121328307 0.848398749259811 0.118320325045946 79.633721607192 0.00148580679965684 0.998815587244658 ERG og 1 1 1 0.191344121328307 0.00148580679965684 0.000443396876173517 1090.30870604525 425.747988141107 2.56092509281309 0.0109794408909322 -986.579112219898 683.642818639922 -1.44312071350746 0.150137109654208 ETS2 other 1 1 1 2.56092509281309 -1.44312071350746 0.123024841225126 244.523648134769 154.130279503703 1.58647378647551 0.113824357885189 -117.543089515914 306.445640709704 -0.383569135601646 0.70160536487272 TSPAN18 other 1 1 1 1.58647378647551 -0.383569135601646 2.50797864685509e-07 15.0371486393571 3.63812720704056 4.13321134298354 4.76812773971698e-05 -8.1172815579367 5.86845798641033 -1.38320519235786 0.167736250859697 LCA5L other 0.00234019487538048 1 0.461077952430632 4.13321134298354 -1.38320519235786 0.00401770895466653 372.449157363226 285.982060405504 1.30235147209974 0.193906085811779 -815.12512230489 416.544775784556 -1.95687275340235 0.051392891254196 MX1 other 1 1 1 1.30235147209974 -1.95687275340235 0.31309225270434 -32.2476750072523 87.3302590581524 -0.369261185699436 0.712225724441321 -279.714647312109 188.018452808521 -1.48769784632242 0.138010623810398 CREB3L1 other 1 1 1 -0.369261185699436 -1.48769784632242 1.0538657326565e-07 19.5943797370947 43.5140443833771 0.450300127573985 0.652854066713714 -299.611429418004 63.2158527536669 -4.73949834364332 3.4637756516355e-06 C2CD2 other 0.00100844411957901 0.0537716532159895 1 0.450300127573985 -4.73949834364332 0.000114346794602576 473.218329915349 118.028107145882 4.00936981333145 7.89848576613865e-05 -49.984712234202 261.801485467928 -0.190926006950886 0.84872812011275 SLC38A10 other 0.841363714685754 1 0.74909239006059 4.00936981333145 -0.190926006950886 1.7676859858191e-24 34.3211616740887 4.24455173866706 8.08593316496286 2.06930914067279e-14 -30.282200923739 7.98268765795079 -3.79348437785584 0.00018322734508987 C9orf43 other 2.69872619455001e-20 1 3.00045072978469e-10 8.08593316496286 -3.79348437785584 0.000366813097164283 135.852467756638 45.7168962634358 2.97160303651874 0.00322747018508842 -94.8857116611391 85.7294517613101 -1.10680413453853 0.2693564964159 ZNF618 other 1 1 1 2.97160303651874 -1.10680413453853 0.267227339206563 12.1563065382886 7.76108482885971 1.56631538069075 0.11843316995881 4.14270958222972 21.2770350839725 0.194703329946112 0.845770019723249 DGKI other 1 1 1 1.56631538069075 0.194703329946112 1.47551133529413e-07 104.427728812375 26.3662992845063 3.96065172762944 9.56053802693972e-05 -101.730897876557 49.0229813963252 -2.07516750264771 0.0389144449141142 TMEM268 other 0.00139716168339001 1 0.898690574532334 3.96065172762944 -2.07516750264771 1.68849501973151e-05 21.9325501754555 4.87214507127687 4.50162091945007 1.00098081278501e-05 2.8094208456897 13.504857451862 0.208030396152189 0.835360913936908 SVOPL other 0.135687459785624 1 0.10280072947302 4.50162091945007 0.208030396152189 1.10367951391406e-07 1289.62980935933 278.895302432187 4.62406429263147 5.81392860563841e-06 -772.58190211847 552.640073472246 -1.39798385821775 0.163252701972722 SNX22 other 0.00105445540759349 1 0.0608369489294003 4.62406429263147 -1.39798385821775 7.27623585183791e-13 147.767084380547 24.6035471740496 6.00592602908916 6.0520439326896e-09 -168.633536624661 67.9133043525345 -2.4830707065775 0.0136264122969793 UBN2 other 9.01671146759754e-09 1 7.58502666083987e-05 6.00592602908916 -2.4830707065775 4.22606947805617e-12 142.164843489112 24.6739417719111 5.76174025225887 2.24241263872794e-08 -166.421132338553 68.1076149417972 -2.44350257281468 0.0151790883978325 BRAF og 5.08058072651913e-08 1 0.000273574341924808 5.76174025225887 -2.44350257281468 0.0185001675716772 -3411.64830806343 2951.44834037837 -1.15592343643259 0.248745762180581 -11562.5714372396 4251.5783076004 -2.71959507756675 0.0069649295101566 SLC34A2 other 1 1 1 -1.15592343643259 -2.71959507756675 0.92648263861993 3.80834275162351 9.78464109263684 0.389216396960065 0.697420611914535 3.23816075663564 21.0134349998826 0.154099544251272 0.877645520885825 ACAN other 1 1 1 0.389216396960065 0.154099544251272 1.54586257666061e-07 214.642702439443 48.673550812708 4.40984269393806 1.49511958651595e-05 -306.295736437247 119.38987420089 -2.56550849464722 0.010842904991161 PSMG3 essential 0.00146192223874793 1 0.151350955743009 4.40984269393806 -2.56550849464722 0.648806429842163 0.153220530124922 3.89611896549712 0.039326450624788 0.968658967356296 -7.0741512419331 8.12982103982875 -0.870148458038151 0.384986535124831 CABP1 other 1 1 1 0.039326450624788 -0.870148458038151 1.90713113718616e-12 114.928391303564 30.4267927936238 3.77721017404269 0.000194830645108154 -141.763203663343 48.9951652778417 -2.89341209197749 0.00411927459899766 WDR19 other 2.32612784802597e-08 1 1 3.77721017404269 -2.89341209197749 3.28492772061581e-18 217.238984480728 26.5113624365767 8.19418409749519 9.85597044052505e-15 -125.475821806656 73.1794571416361 -1.71463176563065 0.0875476128574798 SLC37A3 other 4.6718242042598e-14 1 1.43621201259331e-10 8.19418409749519 -1.71463176563065 5.33559054275566e-07 222.465274017751 43.5796241030435 5.10480020414435 6.22995620290442e-07 -36.417891046164 92.9455031955925 -0.391819827684691 0.695498146779709 AP3S2 other 0.00486125654350468 1 0.00700247077206457 5.10480020414435 -0.391819827684691 0.00086261687727636 411.09935925959 123.116197174654 3.33911677499589 0.000958343476416017 -143.858314907483 288.141055037494 -0.499263511368637 0.617998817064956 FMNL2 other 1 1 1 3.33911677499589 -0.499263511368637 0.000236363120951765 115.111708880901 27.7895956881547 4.14225921717773 4.59457805807763e-05 43.4502892632579 103.612030044904 0.419355640888681 0.675287239530639 GAREM2 other 1 1 0.445260559608303 4.14225921717773 0.419355640888681 2.78790644731411e-11 313.952469200251 75.4307300314997 4.16212953353555 4.23876555543754e-05 -683.80490707872 158.646512238769 -4.31024229545978 2.28443317902994e-05 SPPL3 other 3.2484685924104e-07 0.348376059802066 0.412431888544073 4.16212953353555 -4.31024229545978 0.080976885704059 67.6478440023306 30.032662356734 2.25247576118281 0.0250866872357586 10.9594564222092 112.076486458018 0.097785510311429 0.922174367556556 DPYSL5 other 1 1 1 2.25247576118281 0.097785510311429 0.604735191069745 5.85175643053356 14.1077508210872 0.414790174900652 0.67862127582658 -47.2461208690586 52.6475849883531 -0.897403382880916 0.370294421206913 DRC1 other 1 1 1 0.414790174900652 -0.897403382880916 4.87723057301863e-23 67.8176423161093 16.146983444252 4.20001931322046 3.62465370794614e-05 -118.076316482287 23.5480888723586 -5.01426324328546 9.63377233457678e-07 RAB28 other 7.36608133443004e-19 0.0150884142304142 0.354889844545007 4.20001931322046 -5.01426324328546 2.76629277259707e-08 196.096732806427 71.1194957297723 2.75728519717746 0.00622896698922239 -359.667085093397 113.060086221271 -3.18120299669231 0.00163919465796853 FAM213B other 0.000274554557680259 1 1 2.75728519717746 -3.18120299669231 0.00181635275511404 53.1487890840598 97.0038749770744 0.547903772881453 0.584215731300702 -422.605702179957 154.603642918949 -2.73347829456715 0.00668575686095199 TNFRSF14 other 1 1 1 0.547903772881453 -2.73347829456715 2.05017548240694e-16 128.087878606763 24.3559531261424 5.25899676121811 2.97231246776269e-07 -138.11830256042 38.8182336113346 -3.55807798838354 0.000441957939362646 PANK4 other 2.80792034070455e-12 1 0.00341518702545933 5.25899676121811 -3.55807798838354 0.00139894825847812 32.4697094484445 10.4740859181437 3.10000411512751 0.00213984635462326 64.567484037495 21.0918665295469 3.06125036146253 0.00242637888390952 MEGF11 other 1 1 1 3.10000411512751 3.06125036146253 4.1698049095773e-15 92.5951494614109 13.9230146027962 6.65051011602148 1.59673623368549e-10 -88.4963485698457 28.8247466581245 -3.07015182542471 0.00235595739009948 C12orf43 other 5.53208017353621e-11 1 2.12222212819139e-06 6.65051011602148 -3.07015182542471 2.36379826885682e-17 222.078434741844 44.5251388227948 4.98770897999199 1.10184852592006e-06 -295.835989133368 70.963646195607 -4.16883862362307 4.14093207874676e-05 PEX10 other 3.31049947553397e-13 0.626812888759897 0.0121787317569944 4.98770897999199 -4.16883862362307 6.90476399284379e-23 570.331393041287 108.35942767308 5.26332969164412 2.90952470888503e-07 -965.324757821482 172.701990171319 -5.58954043820739 5.61653621403134e-08 RER1 other 1.04130745776077e-18 0.00088909768268116 0.00334478960533423 5.26332969164412 -5.58954043820739 0.471908660771153 7.9621730298885 8.46125821258457 0.941015252087003 0.347532007421602 -13.3701488206277 23.6231034812888 -0.565977659591501 0.571875594991631 RADIL other 1 1 1 0.941015252087003 -0.565977659591501 7.14706455792765e-07 412.987503280257 154.528670368457 2.67256232966693 0.00799066762914788 -651.971641322712 246.285989915672 -2.64721367847983 0.00859818909139125 SKI other 0.00643950516669281 1 1 2.67256232966693 -2.64721367847983 3.80489253738991e-14 336.309445111678 44.9353221079083 7.48430030843129 9.92741434298885e-13 -255.261361733133 124.888120923515 -2.04392026916205 0.0419209845449696 WIPI2 other 4.91363822278532e-10 1 1.39877268092713e-08 7.48430030843129 -2.04392026916205 1.1538681881927e-11 215.459302840256 76.7789372539156 2.80622929342862 0.00537601612967667 -451.745189634078 110.67169572174 -4.08184935351396 5.88370190095082e-05 LDLRAP1 other 1.36537222708842e-07 0.885673647150127 1 2.80622929342862 -4.08184935351396 2.88213425974088e-09 222.020474653276 66.6964762396932 3.32881865985515 0.000992105793316342 -332.226954806314 106.657396141093 -3.11489842079798 0.00203603914275374 AGAP1 other 3.03459916208117e-05 1 1 3.32881865985515 -3.11489842079798 0.000975679331201019 272.119963988296 72.1587096009478 3.77113123964071 0.000199251105184029 0.545802385775488 269.90034046712 0.00202223674423997 0.998387966521199 KRTCAP3 other 1 1 1 3.77113123964071 0.00202223674423997 2.29384567176961e-12 41.9877419265074 21.5487759889366 1.94849776841453 0.0523874404192093 -153.784609462323 30.9393474382162 -4.97051884398729 1.18544651681801e-06 PAFAH2 other 2.78885756773749e-08 0.0185344562904495 1 1.94849776841453 -4.97051884398729 0.0239861409213225 180.579685233119 83.4629720716615 2.16359040123892 0.0313665760771255 -166.86609753714 174.309494229566 -0.957297812575699 0.339267045858636 WDR66 other 1 1 1 2.16359040123892 -0.957297812575699 4.32767242475315e-12 361.114558534312 68.6052135893542 5.26366058264627 2.86188477987088e-07 -112.037083207698 104.132267763915 -1.07591129640722 0.282916833612903 MRPL17 essential 5.20013118558339e-08 1 0.00329202606228547 5.26366058264627 -1.07591129640722 0.239657508176723 73.3772964140289 47.9313747926442 1.53088236528717 0.127004966226106 -103.427461356113 214.997166588408 -0.481064299578027 0.630872298123212 DUSP2 other 1 1 1 1.53088236528717 -0.481064299578027 0.951527010495178 16.6890347066619 108.90078006887 0.153249909652691 0.878314829337281 50.9386215321097 162.714420310545 0.313055360642848 0.754478507306367 GRHL3 other 1 1 1 0.153249909652691 0.313055360642848 1.69050842683294e-09 130.808572709913 95.5683148689795 1.36874415845091 0.172212760285856 -615.682382762113 137.539904694663 -4.47639093635349 1.11914886331178e-05 UBXN11 other 1.80411059311612e-05 0.172057946245554 1 1.36874415845091 -4.47639093635349 5.21319003757686e-11 59.2258609164251 10.7746008451252 5.49680324753943 8.97911011283316e-08 -38.6124461776134 20.4913978444607 -1.88432465518946 0.0605992916716719 PTPDC1 other 6.00872283731109e-07 1 0.00106411433947186 5.49680324753943 -1.88432465518946 0.00264007023834915 253.239624628754 73.201564169503 3.45948378975019 0.000628107205254536 117.403654098365 279.980942040886 0.419327305789335 0.675307919642455 GALNT14 other 1 1 1 3.45948378975019 0.419327305789335 5.83497181347426e-06 190.536037041327 40.9038209455959 4.65814764089519 5.02142369066515e-06 -255.925290197552 211.077852262347 -1.21246870505137 0.226396792591676 NCK1 other 0.0487045097270696 1 0.052800270107344 4.65814764089519 -1.21246870505137 0.380488661644462 35.9161477765612 66.4996302846242 0.540095450498551 0.589573128986433 192.65896328889 138.882148977555 1.38721185341124 0.166512769443546 HPD other 1 1 1 0.540095450498551 1.38721185341124 0.122443629148271 43.0835302545896 27.0446355804286 1.59305271932626 0.112322689553546 -85.8005775238682 101.793346280486 -0.842889841615474 0.400038883776586 RHPN1 other 1 1 1 1.59305271932626 -0.842889841615474 1.48513703462596e-14 304.51531137898 98.5881204591649 3.08876272273707 0.00222117969729116 -753.702715959885 154.698783813645 -4.87206620103633 1.89175853767492e-06 TPRG1L other 1.93795531648341e-10 0.0294887320852767 1 3.08876272273707 -4.87206620103633 0.104875791679505 8.43795334945243 3.95982220960157 2.13089197009717 0.0339916618035935 4.33778978808137 8.21331107341908 0.528141421809756 0.597830217892122 LRRC43 other 1 1 1 2.13089197009717 0.528141421809756 5.16691943774521e-05 58.977643387066 19.2441794748758 3.06470034038418 0.00239950698947799 -64.4577860210312 37.1859139454304 -1.73339254524231 0.0841675515075447 AAED1 other 0.395269336987509 1 1 3.06470034038418 -1.73339254524231 0.0881394013107219 46.5726126737082 34.1610606612257 1.3633245505919 0.173911781417265 237.207208532067 133.760876235665 1.77336763340385 0.077290878138855 XDH other 1 1 1 1.3633245505919 1.77336763340385 1.1895438509374e-10 19.0628943079676 8.96353995232567 2.12671493733027 0.0343473170918243 -57.3127285028212 13.0870423266059 -4.37934921218255 1.70215953774023e-05 XKR8 other 1.34793306155101e-06 0.260566582037274 1 2.12671493733027 -4.37934921218255 1.2853992627579e-09 197.257215185629 30.0765705288971 6.55850091007241 2.80234110475899e-10 -9.88876361797313 136.735253475149 -0.0723205125719121 0.942400985358654 CNNM4 other 1.38129004775964e-05 1 3.68872159619425e-06 6.55850091007241 -0.0723205125719121 1.6929061455236e-17 194.843881540138 41.538976911128 4.69062783989611 4.32376505627526e-06 -252.763728499489 60.6481760477665 -4.16770536183004 4.14254322235943e-05 EYA3 other 2.37616306585693e-13 0.627015342136323 0.0457454342953922 4.69062783989611 -4.16770536183004 0.0102979374693105 33.8017636295714 11.3429307242809 2.97998501896997 0.00314718063349978 61.52617126288 58.6379848620366 1.04925453027826 0.295006257500562 DZIP1L other 1 1 1 2.97998501896997 1.04925453027826 8.66548115925734e-17 156.372267096563 22.2799169525412 7.01853007036133 1.81122531388723e-11 -104.158532424849 42.3254461870345 -2.46089626473342 0.0144851571853198 FANCC other 1.19808942507892e-12 1 2.47413377876996e-07 7.01853007036133 -2.46089626473342 0.680766684879163 17.600165801005 20.0617967015333 0.877297585198827 0.381107854967831 9.97844939403679 103.58020741714 0.0963354838038836 0.923325861094429 MRAS other 1 1 1 0.877297585198827 0.0963354838038836 2.12271475749483e-09 1354.60950764007 413.550341911943 3.27556132919001 0.00119179673554444 -1712.47197701007 607.178500836448 -2.82037650320453 0.00515113530353707 WASF2 other 2.25368625803226e-05 1 1 3.27556132919001 -2.82037650320453 8.16775256950441e-07 397.450827486736 79.1314037525195 5.02266873376527 1.02813914876201e-06 -11.5480864260082 174.590268604028 -0.0661439295462642 0.947321198360449 ABHD3 other 0.0073207566280468 1 0.0113938380465806 5.02266873376527 -0.0661439295462642 0.0220808215041712 28.0961812622565 10.5912452410606 2.65277411888568 0.00845967039735417 -25.7230308607295 54.4552846670678 -0.472369780417027 0.63704728782174 ESYT3 other 1 1 1 2.65277411888568 -0.472369780417027 1.13410785606726e-05 39.1316405867953 8.83593339528871 4.42869347653301 1.3820397943281e-05 -64.6348738292973 45.4350015202015 -1.422578885588 0.15602115809807 FAIM other 0.0924071081123607 1 0.140235577930473 4.42869347653301 -1.422578885588 0.00536933000962016 -15.1449402495292 39.6418233465458 -0.382044491675704 0.702728886319643 -165.513116394797 57.445567281359 -2.88121650159952 0.00427946544686046 FAM46B other 1 1 1 -0.382044491675704 -2.88121650159952 0.0710638193526425 125.135193010509 57.4231875017778 2.17917532018986 0.0301831560615001 -153.639839175214 295.588336956024 -0.519776391576882 0.603645302396912 CLSTN2 other 1 1 1 2.17917532018986 -0.519776391576882 0.227084053054089 -93.0230489948003 91.9936044800377 -1.01119039220804 0.312910855675695 -340.824353538997 202.21285387905 -1.68547323773421 0.0931550733301837 COLEC12 other 1 1 1 -1.01119039220804 -1.68547323773421 0.00172083005410345 9.63457948650119 35.0061796563448 0.275225105426634 0.783354582604044 -156.354678227256 54.959190470701 -2.84492324010138 0.00478370413111091 RNF207 other 1 1 1 0.275225105426634 -2.84492324010138 2.57264637755127e-05 24.5672168252066 83.0871772991181 0.295680002905422 0.767702582281023 -486.909498012741 130.445654101175 -3.73266170780278 0.000231202750413726 GPR153 other 0.203033252116346 1 1 0.295680002905422 -3.73266170780278 0.00648269402533523 17.2648132516253 7.7078970428359 2.23988633419437 0.0259153005228815 -39.7054717610521 25.5656032303707 -1.55308174828763 0.121579301609454 SLC13A3 other 1 1 1 2.23988633419437 -1.55308174828763 0.00350449326099611 -29.4457908328247 27.052554310307 -1.08846619417398 0.27735996357525 -142.401910373446 42.7839120604341 -3.32839853850433 0.000994930865003085 RHBDL2 other 1 1 1 -1.08846619417398 -3.32839853850433 0.0154715632015231 180.25763328133 101.837260712884 1.77005579312999 0.077876411231079 -488.819075203455 307.177780568439 -1.59132302570481 0.112738124072486 AUTS2 other 1 1 1 1.77005579312999 -1.59132302570481 0.00123335597073254 117.308144694707 36.1998243554255 3.2405722067302 0.00134187204231891 -29.761328455575 63.5350947574372 -0.468423452726357 0.639858342615272 HIST1H2BD other 1 1 1 3.2405722067302 -0.468423452726357 5.44125805632738e-11 88.3340066340299 13.1312738547156 6.7269944722315 1.01946621514621e-10 20.2363097912501 21.6375096824739 0.935242090620124 0.350493110013497 CDC25C other 6.26506452605534e-07 1 1.36200686343534e-06 6.7269944722315 0.935242090620124 0.0588895557942367 80.3451954606381 33.5851712796615 2.39228184342456 0.0174255457252101 53.7778487246918 58.347652271171 0.921679735711713 0.357515439348764 HIST1H4H other 1 1 1 2.39228184342456 0.921679735711713 1.96863257884195e-05 70.4119361047574 14.9651404482859 4.70506350061167 4.04374737660791e-06 8.57873606423643 63.9807139477035 0.134083156234369 0.893435974271904 MITD1 other 0.157214997746318 1 0.0428839409289269 4.70506350061167 0.134083156234369 8.20330611079886e-07 728.021490309766 136.973443811107 5.31505575134507 2.22377390103244e-07 -143.127454769958 583.475124198668 -0.245301725530332 0.806407790547035 EIF5B other 0.00735098260588685 1 0.00257468542261536 5.31505575134507 -0.245301725530332 0.0720611579823529 1.03190849803916 4.41854373949218 0.233540405816546 0.815518110160267 -11.7886337141241 6.58120569054302 -1.79125744862586 0.0743677989917451 CATIP other 1 1 1 0.233540405816546 -1.79125744862586 2.01280826723241e-11 314.564833844212 47.4673869901309 6.6269675621625 1.83192735801979e-10 -317.202032853492 182.861808081052 -1.73465436102926 0.083934869431596 CNOT11 other 2.35961513167655e-07 1 2.42876929126264e-06 6.6269675621625 -1.73465436102926 0.202217075894016 6.58853530031611 3.68393025991758 1.78845277610209 0.0748282747850445 4.24791545279857 12.1197419070881 0.350495537393764 0.726241142303747 KCNB1 other 1 1 1 1.78845277610209 0.350495537393764 5.66690583924814e-05 245.692019339229 60.4796178181671 4.06239371548124 6.35942549185876e-05 -44.8878239821145 163.487003561196 -0.274565090828839 0.783858809065272 TSPAN33 other 0.431761555892315 1 0.608597019570884 4.06239371548124 -0.274565090828839 0.165388849909813 13.8690598423434 91.1420063204591 0.152169788687548 0.879166248103043 -418.914526953003 246.389045564278 -1.70021571370435 0.0902376353927677 AHCYL2 other 1 1 1 0.152169788687548 -1.70021571370435 1.2691331636896e-08 851.520531194903 159.470124261654 5.33968688578777 1.98235116721276e-07 -878.603905510335 521.566896798885 -1.68454691220391 0.0932358467174717 B4GALT5 other 0.000128436276165388 1 0.00230309558606779 5.33968688578777 -1.68454691220391 0.695045086768223 -1.87226218678966 4.0194424016237 -0.465801471874141 0.64173175291266 9.01635469851961 13.2921845504042 0.678320005588954 0.498147608847116 CD1D other 1 1 1 -0.465801471874141 0.678320005588954 0.170385067295875 -15.3214662236446 8.52389319599727 -1.79747280630398 0.0733737584364079 -19.9856748264605 28.1882784048258 -0.709006578530136 0.478929882778704 CD1A other 1 1 1 -1.79747280630398 -0.709006578530136 1.36356435246579e-15 102.087795037546 12.83166617265 7.95592666329964 4.97264144820734e-14 -69.9656331733884 42.3431598216818 -1.65234794635148 0.0996303367147984 SPATA2 other 1.83044878675008e-11 1 7.16657085515641e-10 7.95592666329964 -1.65234794635148 0.137987458264188 -4.54637765528735 4.43643704746505 -1.02478128431578 0.30638026596445 23.9588621493591 14.67117427963 1.6330568837032 0.103618304377886 CD1C other 1 1 1 -1.02478128431578 1.6330568837032 1.61588794002587e-15 62.4366274518243 8.22376067912315 7.59222330123565 5.59593015708506e-13 -36.1356830516078 21.6342440285109 -1.67030024270717 0.0960587137103368 FAM86C1 other 2.16528983963466e-11 1 7.9277542535424e-09 7.59222330123565 -1.67030024270717 0.0171308182013044 -4.43750510495375 11.8084319200897 -0.375791225709166 0.707367191800743 -61.4941611399044 23.1259721702329 -2.65909518039886 0.00830311465151693 DNAH3 other 1 1 1 -0.375791225709166 -2.65909518039886 0.209109567821841 -4.65703398315895 2.83121496588216 -1.64488886901172 0.101152131160975 5.06430578081424 9.43568124293289 0.536718616327495 0.591902332161258 CD1E other 1 1 1 -1.64488886901172 0.536718616327495 0.137490785105575 -24.2684751580489 12.70575283618 -1.91003834805787 0.0571916767598554 -48.768471421668 43.1669203487877 -1.12976489931688 0.259581696780548 NCF1 other 1 1 1 -1.91003834805787 -1.12976489931688 0.424555022934736 -4.73458421780193 19.0317978728841 -0.248772304614879 0.803730335590397 -102.295692083451 78.0296071760021 -1.3109856089973 0.191001813200191 PPP1R9A other 1 1 1 -0.248772304614879 -1.3109856089973 1.13992137287698e-26 484.022894614366 52.5425533039711 9.2120170067522 9.12436350853063e-18 -101.554445220638 86.0919090809257 -1.17960498616865 0.239191851459608 ZC3H18 essential 1.76106452895764e-22 1 1.37531531164082e-13 9.2120170067522 -1.17960498616865 3.19737879856232e-15 33.4825883293912 28.0990236668176 1.19159258792793 0.234467393203895 -275.157850519731 41.6904206214927 -6.60002577133698 2.16688389100251e-10 ZFAND2B other 4.25251380208788e-11 3.4535795454798e-06 1 1.19159258792793 -6.60002577133698 0.0126382364082445 35.7176069693018 15.6231494066652 2.28619761864812 0.0230145315933375 -31.9329441744695 37.3953142353972 -0.853929023659408 0.393898501922977 GDPD5 other 1 1 1 2.28619761864812 -0.853929023659408 2.26236467627706e-06 159.007214381197 31.3354511961042 5.07435534871012 7.32491472400195e-07 -36.0633810902351 129.619034807908 -0.278225965373683 0.781055866736805 DYNC1I1 other 0.0195558802617389 1 0.00819657957615819 5.07435534871012 -0.278225965373683 1.06442752778139e-14 441.746617847833 68.6158182258064 6.43797056232863 5.5095221793484e-10 -668.362417214287 198.833238588459 -3.36142197330322 0.000887486202087242 TMED4 other 1.3954644889214e-10 1 7.18276406521651e-06 6.43797056232863 -3.36142197330322 4.38210584707598e-07 336.321737747743 62.5211508326211 5.37932736791952 1.61295277159353e-07 -168.467753989437 183.867567183065 -0.916245081013689 0.360349985246836 PPP1R15B essential 0.00402058211469221 1 0.00188432661153775 5.37932736791952 -0.916245081013689 2.58309083810242e-13 221.764040120082 42.4650135767258 5.22227644457005 3.52557200879658e-07 -424.531019091898 113.998861415902 -3.72399350150596 0.000238548581832921 COPG2 other 3.25004489250047e-09 1 0.00403380738789959 5.22227644457005 -3.72399350150596 1.93257909536281e-19 189.787644787645 21.8556531915311 8.68368669306973 3.66478071665654e-16 -61.5659945659943 51.6606099463234 -1.19173959869933 0.23440596610717 EMSY other 2.80243294618562e-15 1 5.44109993001996e-12 8.68368669306973 -1.19173959869933 1.95383612092012e-18 509.480187282231 63.2084002074448 8.06032403304242 1.04656496939236e-13 -327.215739795919 160.365596092628 -2.0404360272319 0.042775796637416 GPAT4 other 2.79105489873439e-14 1 1.50129744859334e-09 8.06032403304242 -2.0404360272319 0.106072336515823 3.88829605912991 2.49640251582218 1.55755974226348 0.120496127630311 -6.08516097732369 6.96952459599408 -0.873109907786437 0.383370492614922 PKD1L1 other 1 1 1 1.55755974226348 -0.873109907786437 3.35434817956548e-06 39.1367474095245 10.2236034960979 3.82807758775679 0.000160443475793898 -33.4243202510863 18.571876822932 -1.79972765110174 0.0730158467333473 ZSCAN12 other 0.0285723377935387 1 1 3.82807758775679 -1.79972765110174 9.61268294733331e-08 3967.51497059143 679.120945863232 5.84213312040953 1.46851710695908e-08 -124.061919766208 2535.28150790596 -0.0489341792536003 0.961007662518036 TAGLN2 other 0.000921567914160844 1 0.000180921307577359 5.84213312040953 -0.0489341792536003 0.00189804057432073 185.74184959045 55.7116904121116 3.33398337434167 0.000974579625422151 -152.35564004595 157.52744551002 -0.967168860973239 0.334315642227591 ELK4 og 1 1 1 3.33398337434167 -0.967168860973239 0.384422726011481 -2.20683352080993 34.358008215427 -0.0642305429049592 0.948833836345487 176.304743157105 128.052920831887 1.37681157143276 0.169702661162598 SLAMF8 other 1 1 1 -0.0642305429049592 1.37681157143276 0.825419142633511 -11.6558357235612 19.2482196334068 -0.60555396527851 0.545314064326495 3.81979822195591 54.4252534259347 0.0701842983083972 0.944098354857648 SLC45A3 other 1 1 1 -0.60555396527851 0.0701842983083972 1.0906372040877e-09 335.689833451808 50.9614961326042 6.58712673149013 2.30976062665442e-10 -103.486083524871 187.848325297151 -0.550902348270444 0.582152819021171 DUSP23 other 1.17516158740449e-05 1 3.05026988355983e-06 6.58712673149013 -0.550902348270444 0.000146375480706606 22.2749118710285 20.5704084762075 1.08286191286831 0.27983940511003 -91.8023506672356 33.8340966080191 -2.71330875864075 0.00709150139276518 RNF166 other 1 1 1 1.08286191286831 -2.71330875864075 0.000283197170300587 30.8790702061109 365.330713357891 0.084523608547143 0.932702082197108 -1741.90992579568 535.738325454513 -3.25141929003841 0.00129246754363206 NBL1 other 1 1 1 0.084523608547143 -3.25141929003841 0.624701370364834 -10.9750818236017 22.201371991507 -0.494342504048856 0.621463317207736 62.903800995267 78.4536431582223 0.801795792560009 0.423371005577254 ITLN2 other 1 1 1 -0.494342504048856 0.801795792560009 6.82109155125053e-07 2258.03895870379 431.066357964507 5.23826301214096 3.25928773674758e-07 -1846.26002405642 1462.61753886686 -1.26229856746199 0.207926577975313 F11R other 0.0061560351250036 1 0.0037354696750864 5.23826301214096 -1.26229856746199 4.2192767554014e-09 234.840451189266 38.026626896519 6.17568452306674 2.41092855250466e-09 -186.808093468779 129.0496137265 -1.44756801724869 0.148898005656526 USF1 other 4.39184517469732e-05 1 3.07007641875944e-05 6.17568452306674 -1.44756801724869 0.0460884461404415 10.1995241672085 9.63039201420598 1.05909750632819 0.29049153801956 -16.7951342223479 14.1224646669849 -1.18924951263012 0.235374831881356 PLA2G2F other 1 1 1 1.05909750632819 -1.18924951263012 3.11291321707062e-06 41.113766950126 16.2517194638261 2.52981027894551 0.011996911773271 -57.9426593805824 26.4817385988554 -2.18802323587194 0.0295480402802188 SPATA2L other 0.0265905047002172 1 1 2.52981027894551 -2.18802323587194 2.75978396683008e-18 191.645549118656 19.9415029116338 9.61038643716521 5.24407413682011e-19 -52.4700104899459 69.5577914986556 -0.754336924152631 0.45130190599076 NIT1 other 3.93103628235276e-14 1 7.98043202141284e-15 9.61038643716521 -0.754336924152631 1.63384630488915e-19 240.524595832508 24.0542886331558 9.99923961588184 3.05591792421683e-20 -63.4775451555892 83.9035653836009 -0.756553608483436 0.449974538024758 DEDD other 2.37218145006856e-15 1 4.6819718516926e-16 9.99923961588184 -0.756553608483436 1.43504151086237e-05 96.1360606757056 55.5588619833029 1.73034610940371 0.0847414846764055 -240.651802166876 90.5316673209009 -2.65820578907329 0.00833712325971182 ZNF276 other 0.11605180698344 1 1 1.73034610940371 -2.65820578907329 0.00129623088335038 20.1818296633901 14.4213655869548 1.39943957052487 0.162820600544362 -45.3389105485698 23.9705926810359 -1.89143886227057 0.0596281314784011 NPM2 other 1 1 1 1.39943957052487 -1.89143886227057 0.827962494702375 10.4267079399404 30.8173868785846 0.338338483435338 0.735368179577881 27.7403865046724 45.1920811405828 0.613832906220407 0.539836890777161 CDA other 1 1 1 0.338338483435338 0.613832906220407 8.68673566393935e-18 364.094190162834 39.2113628503558 9.28542554239554 5.31865668781128e-18 -220.868454766382 136.746168756188 -1.61517106311168 0.10743298432567 B4GALT3 other 1.22639334103496e-13 1 8.03649025528284e-14 9.28542554239554 -1.61517106311168 4.32974469102085e-06 149.251453517104 86.0250208269295 1.73497724362517 0.083877555281434 -397.593732359565 142.987203409174 -2.78062457954231 0.00580438756910091 DMTN other 0.0365993318731992 1 1 1.73497724362517 -2.78062457954231 0.673629366860568 -88.8941923039862 104.064717308104 -0.854220283333859 0.393734646467884 70.2597074472828 362.916521134123 0.19359743454974 0.846635599807135 ADAMTS4 other 1 1 1 -0.854220283333859 0.19359743454974 6.68072385975026e-10 181.356958980836 93.4789237126314 1.94008394382412 0.0534029792689696 -623.763683488001 155.376770047633 -4.01452342777351 7.70888251744818e-05 FAM160B2 other 7.29134202053144e-06 1 1 1.94008394382412 -4.01452342777351 9.46669906120832e-18 629.859453899213 66.6391277449438 9.45179619262054 1.61572674963257e-18 -147.51100373631 232.398079178025 -0.63473417791595 0.526135326410319 NDUFS2 essential 1.33546723656466e-13 1 2.45057276116772e-14 9.45179619262054 -0.63473417791595 0.000361341289905937 15.5065140748898 4.0274743965968 3.85018315398671 0.000147552018359032 5.83559721026773 8.6221922098587 0.676811310654296 0.499107256460429 SLC5A11 other 1 1 1 3.85018315398671 0.676811310654296 0.382138046067266 1.30281864800528 62.3839153654743 0.0208838871425873 0.983353591478148 301.948449984476 217.558401394903 1.38789606858892 0.166304512357871 FCER1G other 1 1 1 0.0208838871425873 1.38789606858892 0.419663402647527 -2.54833828772084 2.28120969560691 -1.11709953391324 0.264937544821739 -6.14468476891616 7.95551756755337 -0.772380265235954 0.440559832748986 APOA2 other 1 1 1 -1.11709953391324 -0.772380265235954 0.283072735963344 5.61093704673271 10.2194778119465 0.549043419828512 0.58342443306564 54.8082883662968 35.8821778950849 1.52745155342994 0.127806511138057 MPZ other 1 1 1 0.549043419828512 1.52745155342994 2.01967354175983e-31 812.799598952989 116.000485477421 7.00686376964517 1.94362821889532e-11 -989.082479960409 193.663480819672 -5.10722246535154 6.18480574129265e-07 CCAR2 other 3.1729071341047e-27 0.00970890805268121 2.65285815597022e-07 7.00686376964517 -5.10722246535154 4.22963404941718e-16 227.712764887111 26.0159480789965 8.75281439660276 2.24221388801519e-16 30.5974494599979 103.187002565159 0.296524258863675 0.767056032692297 CACHD1 other 5.75103341699254e-12 1 3.33798381508821e-12 8.75281439660276 0.296524258863675 2.99641564461963e-06 185.042863943222 83.8135287672935 2.20779230590553 0.0280933923007945 -408.497529715539 137.038397778317 -2.98089832001943 0.00313414299856123 CDC42SE2 other 0.0256283430084317 1 1 2.20779230590553 -2.98089832001943 1.17893459625409e-05 65.1302324079706 20.1775843263708 3.22785083459418 0.00140065181975426 -51.981778834857 32.7238153058092 -1.58849994565362 0.113339304813901 RAPGEF6 other 0.0959770654810454 1 1 3.22785083459418 -1.58849994565362 2.00577090851283e-07 529.274846745976 109.163594674794 4.84845564423491 2.09917804709572e-06 26.4789783065082 158.658955951159 0.166892427520193 0.867579150173384 EPB41 other 0.00188417081224094 1 0.0227404675220338 4.84845564423491 0.166892427520193 3.53235319803095e-15 175.517606818202 27.5794208662525 6.36407876979656 8.51236543557695e-10 -76.8402693685507 39.6300506520185 -1.93893946902228 0.0535623022817534 MIS18A other 4.69414416486332e-11 1 1.10243644756157e-05 6.36407876979656 -1.93893946902228 1.22504102481114e-23 250.680396071705 25.6868181685615 9.75910657469113 1.81688472898564e-19 -102.140984396696 64.6493318428399 -1.57992327971767 0.115295201240896 ALG8 other 1.85899975515091e-19 1 2.77329285032368e-15 9.75910657469113 -1.57992327971767 1.55529263429887e-05 435.142771130422 117.175919859781 3.7135852797327 0.000248428161528627 -314.845026033423 220.28074200436 -1.4292898379069 0.154081203624811 FBXW5 other 0.125325480471803 1 1 3.7135852797327 -1.4292898379069 1.46914836277823e-16 237.710827310364 41.6833608185902 5.70277498364162 3.09885824976053e-08 -200.816542285991 59.6769253428993 -3.3650618079285 0.00087675969240613 C21orf59 other 2.01860985045729e-12 1 0.000375612608453474 5.70277498364162 -3.3650618079285 6.02277268584939e-08 40.9938249947372 18.9593310243568 2.16219786141573 0.0314845867118047 -101.20293364346 27.1435546432055 -3.72843332326013 0.000234920710514964 SYNJ1 other 0.000584751000069117 1 1 2.16219786141573 -3.72843332326013 2.07488859282958e-08 158.07438074521 46.1873752099819 3.42245862698532 0.000717190879191159 -180.174890203784 66.125199313614 -2.72475383173157 0.0068567819063908 PAXBP1 essential 0.000207364365967388 1 1 3.42245862698532 -2.72475383173157 0.0200093571272226 -35.3701908429103 54.5106356484688 -0.64886770117684 0.516983700268479 -211.692403639353 78.4708033158567 -2.69772188755681 0.00742787298971528 IFNAR2 other 1 1 1 -0.64886770117684 -2.69772188755681 2.01690986819865e-22 300.072737266396 30.4441008222096 9.8565150279455 8.91895668151939e-20 -79.8452297627236 64.3710172382173 -1.24039098942993 0.215907614828975 MRPL10 essential 3.02980200400801e-18 1 1.36415442443839e-15 9.8565150279455 -1.24039098942993 1.8179032424779e-06 384.666683269229 157.233153876485 2.44647311197106 0.0150740459269655 -636.914710699487 226.345037914084 -2.81391064089175 0.00525968861538021 IFNGR2 other 0.0158684774035896 1 1 2.44647311197106 -2.81391064089175 5.22188309411583e-18 739.856333618214 105.941141671775 6.98365452687326 2.29856316748154e-11 -348.745494434105 151.59827361708 -2.30045821837652 0.0221963475062341 GART other 7.40045272098096e-14 1 3.13041317779311e-07 6.98365452687326 -2.30045821837652 2.45498845584923e-16 182.037876306939 38.2698878536926 4.75668695458103 3.23042807995092e-06 -239.060619130917 54.7629451465949 -4.36537184935864 1.81857341014047e-05 DONSON essential 3.35670571568265e-12 0.278057362400429 0.0344977414657958 4.75668695458103 -4.36537184935864 0.010533913188602 126.099328660415 41.4272800679219 3.04387177853988 0.00257509825986696 18.751381022212 139.237282955887 0.134672126776223 0.892975305278487 SV2A other 1 1 1 3.04387177853988 0.134672126776223 0.365607545705652 10.8873765065591 337.725674567025 0.0322373373612092 0.974306336763222 -1309.43196263166 929.829602680481 -1.4082493812381 0.160195012219201 LAD1 other 1 1 1 0.0322373373612092 -1.4082493812381 0.00488006648768806 285.557253409523 240.506405532131 1.18731662376191 0.236138605206234 -678.559125143427 404.321567232188 -1.67826596485701 0.0944436970015316 STC1 other 1 1 1 1.18731662376191 -1.67826596485701 0.229646550911904 10.6884464703797 6.23800067575241 1.71344105683196 0.0877666261707505 5.81748766832886 17.1891732395944 0.338439062032872 0.73529247934534 TNNI1 other 1 1 1 1.71344105683196 0.338439062032872 0.634785669786567 145.359735676636 277.900981580648 0.523063052350006 0.601354644061665 -563.066847465189 765.772298552517 -0.735292786810796 0.462792401348159 CSRP1 other 1 1 1 0.523063052350006 -0.735292786810796 0.24310900443739 1.13809121333444 41.4585743377718 0.0274512867727234 0.978120071425293 -144.644511124564 91.3722529015809 -1.58302445798686 0.11458649785717 HOXB13 other 1 1 1 0.0274512867727234 -1.58302445798686 0.465916755804114 -683.527862043212 603.900305724116 -1.13185546614953 0.258692062512462 -960.84566201521 896.312113595134 -1.07199896937823 0.284670707453073 C1QC other 1 1 1 -1.13185546614953 -1.07199896937823 1.71959052000339e-08 460.648118577528 82.981730517121 5.55119923032319 6.77831394078002e-08 -136.173115823564 182.88684037341 -0.744575801875807 0.457175762256749 ATP5G1 other 0.00017266408411354 1 0.000807930334525638 5.55119923032319 -0.744575801875807 0.326829374800404 196.818067902928 137.898310645584 1.4272696088988 0.154661956193685 62.3289710756359 195.294373661743 0.319153951580766 0.74985746810883 RCAN1 other 1 1 1 1.4272696088988 0.319153951580766 4.82731475117878e-14 745.944753473653 100.440342918305 7.42674439174685 1.46295923326624e-12 -232.297071631411 221.364592517875 -1.0493867559811 0.29493853808252 UBE2Z other 6.21613320509291e-10 1 2.05282439611919e-08 7.42674439174685 -1.0493867559811 0.000958302242526606 64.1338835029242 16.9976172595411 3.77311022619505 0.000199244470004806 -5.21633454279071 57.696229655492 -0.0904103192520168 0.928029973469433 CIART other 1 1 1 3.77311022619505 -0.0904103192520168 1.8064718532197e-20 424.512552727498 42.8341766986507 9.91060376189909 5.99967154445974e-20 27.7098893246479 94.4039993814816 0.293524527628048 0.769346745140395 SNF8 essential 2.6558749186036e-16 1 9.18429720025897e-16 9.91060376189909 0.293524527628048 0.774176567147692 35.2113458244664 138.165853609676 0.254848393467318 0.799034921516843 -88.3232025150331 195.673273412981 -0.451381023961413 0.652078640195857 CLIC6 other 1 1 1 0.254848393467318 -0.451381023961413 8.12523495102652e-08 87.8140078921324 21.8278213150793 4.02303127850272 7.45755642928313e-05 -75.5522028989232 40.6844730809391 -1.85702793172759 0.0643920844475978 CCDC24 other 0.000782622630482874 1 0.709437343117704 4.02303127850272 -1.85702793172759 8.29847670657978e-05 245.062432674039 55.667566362263 4.40224799983651 1.54479180178986e-05 211.235812683455 122.688033375863 1.72173118169007 0.086263551026993 IGF2BP1 other 0.621057996720431 1 0.156193899078973 4.40224799983651 1.72173118169007 0.0438953040468662 1793.09349592853 779.826225140886 2.29935008354532 0.0222457274566339 229.55738844756 1240.82774684951 0.185003429388496 0.853364723974731 CBR1 other 1 1 1 2.29935008354532 0.185003429388496 0.136563971695154 256.109701194179 128.319173317367 1.99588023031253 0.0469476605843586 161.999061342974 204.176245388791 0.793427565652884 0.428222890845444 CBR3 other 1 1 1 1.99588023031253 0.793427565652884 0.635943855511768 7.98842129226228 8.76492798862642 0.911407521274362 0.362893681552176 12.1499837954162 37.7636746844466 0.321737328184864 0.747900638927677 C2orf81 other 1 1 1 0.911407521274362 0.321737328184864 2.12179269141693e-16 157.199585505492 35.833988803316 4.38688493118426 1.64805018542289e-05 -282.764510073179 57.0175843719748 -4.95925096069421 1.25022681756552e-06 MORC3 other 2.9053707323572e-12 0.019538544704914 0.166189380698045 4.38688493118426 -4.95925096069421 2.68546960508743e-14 197.052845284354 31.123343942857 6.33135197959918 1.00431079594331e-09 -92.3192389925078 49.5221980154113 -1.86419914083333 0.0633748982857221 CHAF1B essential 3.4833226247589e-10 1 1.29736868619957e-05 6.33135197959918 -1.86419914083333 4.10588323463714e-08 106.214582021035 25.6781327430914 4.13638262110829 4.70659914701428e-05 -77.4117072873375 40.9173222054763 -1.8919055088355 0.0595656555100177 SIM2 other 0.000402910321814942 1 0.455410533465102 4.13638262110829 -1.8919055088355 2.0213791125505e-15 157.251798662355 26.6078799178465 5.90997099911303 1.02109663017325e-08 -123.005862943726 42.3988460023854 -2.9011606338721 0.0040217896748487 HLCS other 2.70298814930253e-11 1 0.000126738513737104 5.90997099911303 -2.9011606338721 0.0214595062027091 143.31614961536 54.5753732108583 2.62602234640965 0.00912832655052886 11.798013730595 123.388285476102 0.0956169678918188 0.923895194831379 SCUBE1 other 1 1 1 2.62602234640965 0.0956169678918188 0.00386939427966327 125.606671039938 55.3638997982989 2.26874680969994 0.0240703448964596 -177.464736973083 119.119136830484 -1.48980878887352 0.137437414721966 ARHGAP27 other 1 1 1 2.26874680969994 -1.48980878887352 1.09071953118291e-09 312.159500056751 61.8682275995976 5.04555427184699 8.3515745995686e-07 -237.370046374367 114.808608402473 -2.06752829493624 0.0396442327177165 ADPGK other 1.17516158740449e-05 1 0.00930866504867916 5.04555427184699 -2.06752829493624 1.53086539685774e-11 1512.77723813853 215.118046913538 7.03231207164389 1.64328670597535e-11 -902.650962554729 1017.31828150052 -0.887284716070705 0.375709504239423 PTMS other 1.80397178365716e-07 1 2.24768755643308e-07 7.03231207164389 -0.887284716070705 0.471393200933445 31.6146803147986 27.0271775709287 1.1697366560689 0.243134701058022 12.2849304733982 47.2525367416361 0.259984570575942 0.79507308784284 PLA2G4D other 1 1 1 1.1697366560689 0.259984570575942 4.55990909901233e-10 734.370030830158 108.00565893311 6.79936623769839 6.60634009340528e-11 19.964708241428 304.742501323593 0.0655133699917635 0.94781320998733 ADIPOR1 other 5.02182789074228e-06 1 8.8855274256301e-07 6.79936623769839 0.0655133699917635 0.222818844975615 4.92901633532892 93.0727076617366 0.0529587723314437 0.957803487837474 -452.577816608899 262.608552347826 -1.72339328846174 0.085949660660069 CYB5R1 other 1 1 1 0.0529587723314437 -1.72339328846174 1.40447233803704e-22 813.135299584989 74.919101718801 10.8535110663364 5.65335654803796e-23 -446.563082806565 297.016858691474 -1.50349406014839 0.133893564079258 PSMD4 essential 2.11246684364151e-18 1 8.77683604082893e-19 10.8535110663364 -1.50349406014839 9.52200245125294e-12 408.299650405942 89.3196112350007 4.57122063968351 7.3561064913083e-06 -288.537584497427 134.243799654884 -2.14935501854986 0.0324852524408661 ATP13A2 other 1.12988081086567e-07 1 0.0763637414862715 4.57122063968351 -2.14935501854986 0.823380610507335 3.7601117687247 6.10420772979135 0.615986862696959 0.538422129661678 3.42550743900264 26.5960357690604 0.128797670026733 0.89761363696508 M1AP other 1 1 1 0.615986862696959 0.128797670026733 9.67060249576231e-20 1500.46702619747 149.075611255674 10.065140860795 2.06356933755737e-20 -572.433117742937 591.010419864126 -0.968566878862372 0.333637873394345 PSMB4 essential 1.40832984145787e-15 1 3.16427722221047e-16 10.065140860795 -0.968566878862372 0.621642167031702 10.496560425885 34.9934177075612 0.299958138230578 0.764437353763669 -36.1977920102575 62.6066984107164 -0.578177622030001 0.563620825792876 IRX6 other 1 1 1 0.299958138230578 -0.578177622030001 0.960204365262022 54.5880066307492 210.149500845354 0.259757964740157 0.795246982934978 84.2824285122257 599.414413739739 0.140607944320839 0.888283742301858 BTG2 other 1 1 1 0.259757964740157 0.140607944320839 0.00349238153230126 1280.06595439619 376.930402723141 3.3960273439031 0.000786967483174064 35.937051940242 1642.17537277104 0.0218838088404657 0.982556864127036 HK2 other 1 1 1 3.3960273439031 0.0218838088404657 0.165232717969772 690.122510918205 371.740230302801 1.85646441967302 0.0644725857459458 1311.06757786129 1709.39211691381 0.766978837031453 0.443761749941657 C1R other 1 1 1 1.85646441967302 0.766978837031453 0.654224391331579 12.7087258842047 17.2658828674272 0.736060008155173 0.462342763128322 -34.8752747993022 67.719306725075 -0.514997516747888 0.606982437522422 CELF3 other 1 1 1 0.736060008155173 -0.514997516747888 8.19936581836363e-08 119.853838575649 76.4490089481815 1.56776183530238 0.118099316310247 -423.943291911967 115.361562718491 -3.67490940588667 0.000286556304483541 ALDH4A1 other 0.000789516934650234 1 1 1.56776183530238 -3.67490940588667 0.687840566500193 6.85736939319287 26.9260882604754 0.254673806564719 0.799167487661319 -28.2127159470851 47.6345213887322 -0.592274575760905 0.554158752553716 STARD9 other 1 1 1 0.254673806564719 -0.592274575760905 9.83397334330136e-06 73.3219521246985 15.0901066303759 4.85894194923075 2.01067195972314e-06 60.9813136352433 61.2737430238621 0.995227492655298 0.320523353875601 THEM4 other 0.0806189134683845 1 0.0218258441227947 4.85894194923075 0.995227492655298 0.0816676091695277 49.2229847796483 42.2610111110131 1.16473750829925 0.245145763471696 368.03132443973 181.715713366767 2.02531370359212 0.0438116472271767 TCHH other 1 1 1 1.16473750829925 2.02531370359212 4.0229350176434e-07 71.1634529617108 27.3660318004886 2.6004301054872 0.00981976342968002 -147.317693180191 48.5113753202071 -3.03676595866016 0.00262342653292908 UBR1 other 0.00370351397724251 1 1 2.6004301054872 -3.03676595866016 3.65979769298121e-19 282.643080124872 106.598761137182 2.65146683797891 0.00848278235171456 -1181.44902589894 191.265516296583 -6.17701009975552 2.36214223807252e-09 AMFR other 5.28621178774207e-15 3.75911315766862e-05 1 2.65146683797891 -6.17701009975552 5.35365820807522e-20 171.057622416365 28.8545663095799 5.9282687038541 9.35872378741537e-09 -247.101390776257 54.3809940723013 -4.54389249390564 8.34907019755428e-06 MED8 essential 7.82490683692274e-16 0.128659171744312 0.000116347654125148 5.9282687038541 -4.54389249390564 0.186912401133395 9.23527600735503 6.91368898150486 1.3357956992368 0.182736775609942 -13.5789149306884 19.3696325064564 -0.70104143308667 0.483878667326426 RGL4 other 1 1 1 1.3357956992368 -0.70104143308667 0.855226532442556 11.5082562783941 29.8598335424919 0.385409257624204 0.700235454885477 -39.0005405040908 102.483063465032 -0.38055595905755 0.703829792274097 SPRR2G other 1 1 1 0.385409257624204 -0.38055595905755 0.302969544772784 -30.8010923956032 19.8873747040554 -1.54877618860987 0.122598232297682 -6.37156436517091 67.9083141642517 -0.093825983513003 0.925316466912249 PGLYRP3 other 1 1 1 -1.54877618860987 -0.093825983513003 0.0144878996212331 9.66182406146666 3.31142400688178 2.91772483420653 0.00382264621588223 5.62660474615829 6.47583677592576 0.868861421442163 0.38569460535026 ISL2 other 1 1 1 2.91772483420653 0.868861421442163 1.42187945097835e-21 120.132016513901 26.3859630145173 4.55287595331673 7.97820255530056e-06 -248.021437769866 47.325350258822 -5.24077342087145 3.20382592978539e-07 RSPRY1 other 2.11774725428716e-17 0.00504250163088922 0.0825743964473609 4.55287595331673 -5.24077342087145 0.700433614679399 9.96486357108657 19.038436388727 0.523407666870528 0.601116741087157 -9.88303813626942 32.9916051590096 -0.299562209496512 0.764739894010989 CCDC17 other 1 1 1 0.523407666870528 -0.299562209496512 1.06213622703015e-27 643.920551723205 101.360933582753 6.35274882504406 8.85615906855855e-10 -1063.20216415775 178.113111030214 -5.96925267324871 7.41452014143380e-09 GPBP1L1 other 1.64886027884161e-23 0.000117846383127949 1.1464297914249e-05 6.35274882504406 -5.96925267324871 1.34690370164922e-14 320.965452497498 57.5085176187381 5.58118111521132 5.80947783924348e-08 -226.639432731983 100.15417855435 -2.26290541246857 0.0244360214730091 NAE1 essential 1.75959499583454e-10 1 0.000695626876471015 5.58118111521132 -2.26290541246857 2.11012429319698e-18 197.755533644431 31.4185501727041 6.29422849104722 1.23220883200005e-09 -171.290384729349 55.2091966551436 -3.10256977291826 0.00212048621866362 TMEM69 other 3.01114736639209e-14 1 1.58782430091527e-05 6.29422849104722 -3.10256977291826 0.424364258614035 -9.38422513344661 17.0840707785549 -0.549296783833647 0.583250815082962 -38.4086006786057 29.8717224695721 -1.28578459838496 0.199607789765692 ADGRG5 other 1 1 1 -0.549296783833647 -1.28578459838496 0.324890406262067 -9.08578475766773 6.30047032152595 -1.44208039939901 0.150425898085396 -13.1184863673736 11.0164552296662 -1.19080830393127 0.234763207850906 DRC7 other 1 1 1 -1.44208039939901 -1.19080830393127 0.837876854834078 13.2779265833626 72.0951167236484 0.184172343242871 0.854015992105775 95.0268091747493 160.277718225382 0.592888457777535 0.553750230017041 ACE other 1 1 1 0.184172343242871 0.592888457777535 0.0265560382714378 -2.62524280616163 4.70904842360961 -0.557489023259887 0.577650170741751 -20.3971581013185 8.24394860303434 -2.47419763070951 0.0139617705309926 TEPP other 1 1 1 -0.557489023259887 -2.47419763070951 3.97513625217895e-05 201.31189021336 127.128030598064 1.58353660688601 0.114461187749413 -629.604559240074 223.663453293058 -2.8149639557569 0.00523480450353515 EFCAB14 other 0.30743703774352 1 1 1.58353660688601 -2.8149639557569 0.025156890816316 30.5028505603495 50.1816756977428 0.60784838561542 0.543797076998178 -294.14584437391 136.354811473902 -2.15720913104858 0.0318685382767309 SPON2 other 1 1 1 0.60784838561542 -2.15720913104858 2.56067696827553e-14 135.634973199959 16.4138947260269 8.26342409671287 6.51061129458576e-15 8.08428356833159 62.8563951650556 0.128615132113494 0.897758297513734 CHCHD6 other 3.32324656942798e-10 1 9.51395628477816e-11 8.26342409671287 0.128615132113494 3.74452846200004e-80 1798.83423145508 71.0203889214664 25.3284198914232 2.06454505534449e-73 53.0988631228983 192.978245695078 0.275154657622906 0.783407087579958 CTBP1 other 5.97926304812166e-76 1 3.29542681734087e-69 25.3284198914232 0.275154657622906 0.291695556757716 -23.8822150609631 15.1803236463094 -1.57323490706796 0.116839824075982 -22.6671203558933 26.2121560703125 -0.864756042772299 0.387943194500176 LRRC36 other 1 1 1 -1.57323490706796 -0.864756042772299 0.0789157002677996 -224.886414826785 145.045230176 -1.55045715432286 0.122207507499103 -559.799746015832 250.452381596753 -2.23515441317364 0.0262282087997471 TPPP3 other 1 1 1 -1.55045715432286 -2.23515441317364 0.0363763894124655 4.05586205627261 18.9327891343201 0.214224223779074 0.83053450287818 -66.0353728606784 32.6916102184532 -2.01994861737963 0.0443799589522981 ZDHHC1 other 1 1 1 0.214224223779074 -2.01994861737963 2.13850304480754e-12 221.998947862785 102.987942425546 2.15558193157685 0.0320000748377847 -899.273505060712 181.581021310789 -4.95246418689066 1.29344310264594e-06 ATP6V0D1 other 2.60362745705318e-08 0.0202087550357401 1 2.15558193157685 -4.95246418689066 0.000184995700625285 14.5048133918431 12.6545139976673 1.14621655122567 0.252709242345357 -48.5935192483948 20.2067916867057 -2.40481121406151 0.0168468208881588 ZFYVE28 other 1 1 1 1.14621655122567 -2.40481121406151 0.220654438427754 26.3538483495217 17.8355454421701 1.47760260178032 0.140679682096486 1.67992044249463 31.4463662517147 0.0534217667328424 0.957435367447956 CARMIL2 other 1 1 1 1.47760260178032 0.0534217667328424 0.0713738131727715 -1.69558915543608 3.26204235299303 -0.519793727963197 0.603633234250134 -12.3219408811577 5.71015076229 -2.15790114729232 0.0318173891481211 C16orf86 other 1 1 1 -0.519793727963197 -2.15790114729232 0.95589128400066 -1.74960842584896 11.9592223549861 -0.146297842277303 0.883794238897991 -9.71566434401569 32.5654149807536 -0.298343022797582 0.765668317207168 PIP other 1 1 1 -0.146297842277303 -0.298343022797582 0.664133923649418 -2.60957329216603 5.47838128083415 -0.476340210436886 0.634215838666271 -13.2879310103589 14.87554762693 -0.893273400321951 0.372503336585402 FAM131B other 1 1 1 -0.476340210436886 -0.893273400321951 2.29296379391317e-16 298.008064914934 88.0990211686916 3.38264898930386 0.000823426605133941 -609.30157750682 138.873573205291 -4.38745517555105 1.64194288625849e-05 RGS12 other 3.13746235921139e-12 0.251447133601625 1 3.38264898930386 -4.38745517555105 7.349595778437e-15 147.265124223068 37.5217264687826 3.9247960603729 0.000110219722688009 -286.891473220796 67.4697858036221 -4.25214738425025 2.92046920330769e-05 PSKH1 other 9.67647780189015e-11 0.443969728286835 1 3.9247960603729 -4.25214738425025 0.000631827226645373 299.922089324606 198.143710573154 1.51365939628892 0.131277609041895 -1474.17594906231 538.023195632488 -2.73998586125884 0.00655221016007855 ZYX other 1 1 1 1.51365939628892 -2.73998586125884 1.36095647649318e-09 327.643979691853 106.571792053999 3.07439683031546 0.00232544111869922 -1610.99367447895 330.084743063784 -4.88054570328218 1.81168161627915e-06 ABR other 1.46003410798188e-05 0.0282441163977919 1 3.07439683031546 -4.88054570328218 0.691492088493582 12.6189378270008 14.6879981265778 0.859132586908963 0.391023878711691 11.5678256347082 40.5594763041698 0.285206484126102 0.775703001734617 LYPD5 other 1 1 1 0.859132586908963 0.285206484126102 4.3417837194151e-09 205.245716080304 38.4887498505022 5.33261581312768 2.04280711681377e-07 -158.964435483232 100.647999541881 -1.57940978665041 0.115408564271629 CCDC117 other 4.51719178167947e-05 1 0.0023714947819091 5.33261581312768 -1.57940978665041 2.15869845592473e-19 27.8613365349602 3.38226925069002 8.23746853662708 7.38076761752089e-15 -24.3264581534963 9.36490322061369 -2.59761981308572 0.00989658752684839 ZNF230 other 3.12903341186289e-15 1 1.07722303377717e-10 8.23746853662708 -2.59761981308572 7.54547404077567e-28 109.454835845421 12.964605711552 8.44258886700213 2.05864024902032e-15 -139.674140910246 36.3117087194345 -3.84653176168189 0.000150136132494936 CCDC107 other 1.1721893922345e-23 1 3.02784807825909e-11 8.44258886700213 -3.84653176168189 1.23458417902134e-13 15.8994364898896 2.48990222038031 6.38556661372074 7.31613808828849e-10 -17.7601003606498 6.89409730402028 -2.5761313740514 0.010517350103928 ZNF222 other 1.56927994995402e-09 1 9.49854208002495e-06 6.38556661372074 -2.5761313740514 1.35159642885295e-06 185.063685197534 35.3699853936517 5.23222396441107 3.40743810726746e-07 172.945801909211 99.0654583409765 1.74577299500239 0.0820093217423461 NPR2 other 0.0119170257131964 1 0.00390083514519979 5.23222396441107 1.74577299500239 0.000157934766534912 2.75955782619915 1.02957155949157 2.68029725642566 0.00780295767106859 -6.19697925022151 2.85802911078707 -2.1682701645103 0.0310019419849909 ZNF221 other 1 1 1 2.68029725642566 -2.1682701645103 0.00711678124877274 3.33063870370393 1.75118531255027 1.90193389576429 0.0582322951632538 -8.96692067877165 5.05836502212943 -1.77269150002876 0.0773949433173011 ZNF233 other 1 1 1 1.90193389576429 -1.77269150002876 1.55963059053177e-17 38.6104688030437 5.10384061077743 7.56498326407619 6.00620778748614e-13 -42.4879837763753 14.7465866321475 -2.88120802706652 0.00427719392726682 ZNF235 other 2.1914369427562e-13 1 8.50118650240789e-09 7.56498326407619 -2.88120802706652 5.49030642134908e-13 192.712636627379 30.7733673832643 6.2623187845274 1.53042807498595e-09 -96.7818108857517 86.6747214191417 -1.11660942546021 0.265176592500227 GNE other 6.83158828008466e-09 1 1.96399834862947e-05 6.2623187845274 -1.11660942546021 4.35703128434848e-14 661.367907825688 119.788262625692 5.52114116465897 7.86080298943177e-08 -765.99276252708 247.022332092165 -3.10090491025437 0.00213202992115301 ARHGAP35 other 5.61969895055267e-10 1 0.000934728083473332 5.52114116465897 -3.10090491025437 0.948415657725981 1.73365981156262 11.7353880513754 0.147729227527285 0.882666316974726 -5.6816269463096 28.382885051492 -0.200177921870946 0.84149156836783 PTGIR other 1 1 1 0.147729227527285 -0.200177921870946 9.59725604826065e-21 483.277349962702 71.7790084642801 6.73285073592509 9.84896671493703e-11 -360.346279504286 114.99577529996 -3.13356102486672 0.00191585380055396 DFFA other 1.41636304760231e-16 1 1.31651138078563e-06 6.73285073592509 -3.13356102486672 0.000537893464887506 56.0110304008609 27.1760084245641 2.0610469913688 0.0402669069938771 -63.8406600304904 38.6726202034547 -1.65079737795443 0.099955673520181 CCDC28B other 1 1 1 2.0610469913688 -1.65079737795443 7.86105055243652e-19 57.0914043583535 9.43045049672225 6.0539424259951 4.77248011800501e-09 -42.4509281678773 13.4199336675791 -3.1632740682194 0.00174034682634432 IQCC other 1.12963296438513e-14 1 6.00712072453291e-05 6.0539424259951 -3.1632740682194 1.71079276960895e-12 51.3359564164649 18.5805981998993 2.76287963735974 0.00612766407555478 -119.009765940274 26.4409844930796 -4.50095819886823 1.01098945226725e-05 TMEM234 other 2.09127308156998e-08 0.155510397547748 1 2.76287963735974 -4.50095819886823 2.83866400399633e-11 248.66863486862 99.581533721906 2.4971360208516 0.0131205536016285 -613.602689281893 142.321734765281 -4.31137724883593 2.28172353727415e-05 BSDC1 other 3.30732743105613e-07 0.34798565666968 1 2.4971360208516 -4.31137724883593 5.91830280518874e-11 41.0023755917497 15.3754276940505 2.66674699446673 0.00812475248968653 -89.1116547218705 21.9745314255391 -4.05522434113446 6.57133718674174e-05 ZBTB8A other 6.80072175344239e-07 0.987211985564212 1 2.66674699446673 -4.05522434113446 6.46423506172496e-06 215.362760475017 68.3080096176245 3.15281855935456 0.00180297985944597 -163.557602589546 108.335272062277 -1.50973546727721 0.132302326941888 ATAD3B other 0.0537371860681196 1 1 3.15281855935456 -1.50973546727721 2.38291948295649e-15 563.56648877029 109.278744366612 5.15714645182614 4.90253279099702e-07 -533.398289335746 173.083326396469 -3.08174276772294 0.00227402568920301 SSU72 essential 3.17905288221226e-11 1 0.00554280357350123 5.15714645182614 -3.08174276772294 2.69006707105371e-23 324.470684039085 49.111492175592 6.60681786818817 2.16835201962947e-10 -309.762331316893 77.146205106987 -4.01526336761882 7.75167008056935e-05 UBE2J2 other 4.0716855187469e-19 1 2.86699504035408e-06 6.60681786818817 -4.01526336761882 8.41633750783661e-10 261.453669531906 66.0173540556771 3.96037789262811 9.57090462845243e-05 -239.092947654863 95.3856674667015 -2.5065919650699 0.0127761271048444 ZNF362 other 9.13425109725507e-06 1 0.899569326028244 3.96037789262811 -2.5065919650699 0.483943316421078 -4.7730277574873 35.2985752729642 -0.13521870842031 0.892539706238478 -54.3299853907964 50.338150961844 -1.07930037859313 0.281417054235717 FNDC5 other 1 1 1 -0.13521870842031 -1.07930037859313 0.143431200352018 45.9033303573843 42.4549798294438 1.0812236995941 0.280555302408278 185.839945350756 94.431255797381 1.96799188765962 0.0500846389271479 CPAMD8 other 1 1 1 1.0812236995941 1.96799188765962 0.549885558127858 37.0728466607649 43.7086431819642 0.84818113677028 0.397082877109878 -23.4222791383893 97.3160918398038 -0.240682488328299 0.809982523129765 NR2F6 other 1 1 1 0.84818113677028 -0.240682488328299 3.92170684805295e-07 28.1030022622209 5.13913793036153 5.46842732050274 1.0285012529938e-07 16.4550030490804 11.4421492501248 1.43810421358566 0.151554020734798 ANKLE1 other 0.00361189200705677 1 0.00121517423041218 5.46842732050274 1.43810421358566 8.97665511659684e-18 152.524087666862 16.0112532624388 9.52605552899923 9.6469665556884e-19 66.0573833946701 62.9932042315018 1.04864301158435 0.295276752109475 CCDC58 other 1.26669580350298e-13 1 1.46595303780241e-14 9.52605552899923 1.04864301158435 0.000659074838140176 87.7819401957383 24.2752621977153 3.6161067790238 0.000356561645729142 -67.663389731622 95.3635266829192 -0.709531118292225 0.47860496177313 KALRN other 1 1 1 3.6161067790238 -0.709531118292225 0.970147069407633 -4.24527954252333 19.1459620632918 -0.221732369911185 0.824689841253481 -8.55243170946412 44.0578297292855 -0.194118315904682 0.846229208177527 CILP2 other 1 1 1 -0.221732369911185 -0.194118315904682 5.88166747717175e-10 32.619847357315 5.95373829766936 5.47888498392418 9.92275906458058e-08 -37.3160801053854 17.3264866643913 -2.15370148768105 0.0321622178598119 FAM86C2P other 6.43748505376449e-06 1 0.0011734654869773 5.47888498392418 -2.15370148768105 0.00016665260094536 54.6292675704648 112.337759582619 0.486294793250596 0.627149734073788 -551.842560062104 164.636691992711 -3.35188075867398 0.000916485212370076 ABCG1 other 1 1 1 0.486294793250596 -3.35188075867398 0.902386688544121 72.0612385357808 202.369813660153 0.356086894742098 0.722051522198869 -16.5632692830968 296.583239722576 -0.0558469497419682 0.955504732884194 TFF3 other 1 1 1 0.356086894742098 -0.0558469497419682 0.349268864705644 12.210641516078 10.6626101678502 1.14518315157909 0.253139916833947 -2.70629791763353 15.6265967254906 -0.173185368840992 0.862634530692874 TFF2 other 1 1 1 1.14518315157909 -0.173185368840992 0.397238859478439 -33.3938729452441 39.9710745126332 -0.835450969292548 0.404197091651768 -79.189641788178 58.5796397186853 -1.35182876112703 0.177553146316894 TFF1 other 1 1 1 -0.835450969292548 -1.35182876112703 0.00331174912960339 161.44214366791 51.0900016540405 3.15995573382688 0.00175679567365567 38.444498946003 74.7117072020614 0.51457128187458 0.607272032562836 TMPRSS3 other 1 1 1 3.15995573382688 0.51457128187458 0.385588167994701 1.57584725149992 7.38192656123484 0.213473710206664 0.831118003842463 -11.4628871412356 10.7949954584995 -1.0618704922391 0.289239852168248 UBASH3A other 1 1 1 0.213473710206664 -1.0618704922391 0.459908114906708 41.1161587464187 33.1660069152219 1.23970783855647 0.216151972586371 25.1442910991242 48.6064675441003 0.517303403632674 0.605364793950855 RSPH1 other 1 1 1 1.23970783855647 0.517303403632674 6.6878310812119e-07 -14.808871680791 40.8959594842762 -0.362110875195012 0.717551382968122 -292.013606890955 60.0669845042322 -4.86146606661069 1.97616639776946e-06 SLC37A1 other 0.00604111781565871 0.0307946009764415 1 -0.362110875195012 -4.86146606661069 0.00767084197057588 52.2969769624864 27.0681306920939 1.9320498174542 0.054395649078722 -43.6892367197837 39.5832098121475 -1.10373152978554 0.270688703122695 PDE9A other 1 1 1 1.9320498174542 -1.10373152978554 1.78945182162915e-11 122.546272667345 24.7219125288913 4.95698997899662 1.26363174890126e-06 -71.8418654322394 35.8735073228769 -2.00264403437422 0.0462115486165385 WDR4 essential 2.10296378077857e-07 1 0.0139125855554029 4.95698997899662 -2.00264403437422 5.26653456366225e-18 197.642396463565 33.631893002275 5.87663609806904 1.22564436354046e-08 -163.421141271938 48.8026142188372 -3.34861449305025 0.000927360028888055 NDUFV3 other 7.4626794767094e-14 1 0.000151587694882684 5.87663609806904 -3.34861449305025 5.33141242026664e-10 31.5878769332024 15.5874683371462 2.02649181059928 0.0436936645530378 -100.3295926035 22.6186853013189 -4.43569514615641 1.3354864299808e-05 PKNOX1 other 5.84749314254845e-06 0.204957102409153 1 2.02649181059928 -4.43569514615641 0.000762214105410925 209.71644163948 65.7741011406752 3.18843493111287 0.0015982750594121 -12.2367779278773 95.4435744470887 -0.12820955207059 0.898078231899613 CBS other 1 1 1 3.18843493111287 -0.12820955207059 3.12903041316785e-15 229.794736009206 43.7259121684835 5.25534459118354 2.99635174638373e-07 -196.999401581041 63.4498576330779 -3.10480446970051 0.00210584456283935 U2AF1 essential 4.16254915863719e-11 1 0.00344220888624563 5.25534459118354 -3.10480446970051 0.00153858842951973 7.65950903848391 4.2374918135086 1.80755724744207 0.0717841917984528 -10.6479629216204 6.15375166287927 -1.73032054345825 0.0847114306835206 HSF2BP other 1 1 1 1.80755724744207 -1.73032054345825 1.37648793625664e-15 369.203421499409 69.4869869150161 5.31327429624991 2.24926653455875e-07 -319.68657190171 101.021886278995 -3.16452784319254 0.00173040375436016 RRP1B other 1.84765975683729e-11 1 0.00260352601375175 5.31327429624991 -3.16452784319254 6.97115555694396e-07 2384.10803111081 1366.63316603063 1.74451205368842 0.0822035335804131 -6899.55311577905 1986.8448239481 -3.47261800852107 0.000599733490613212 CSTB other 0.00628658808125206 1 1 1.74451205368842 -3.47261800852107 5.15477802401004e-14 255.394244563754 61.7194978804911 4.13798318739209 4.68062057466385e-05 -349.960504856234 89.7293201632873 -3.90018005507436 0.000121280782044821 RRP1 essential 6.63059097228412e-10 1 0.452990459215967 4.13798318739209 -3.90018005507436 9.66853180409544e-12 15.5280648861425 114.501878863743 0.135614061884705 0.892227065944085 -1042.56048288528 166.034670421025 -6.27917338132805 1.34723926619725e-09 AGPAT3 other 1.14707461323788e-07 2.14520908356588e-05 1 0.135614061884705 -6.27917338132805 1.00508481128471e-18 182.896658063062 37.7473300539805 4.84528727731235 2.13023601701895e-06 -258.373551012907 54.8779944756081 -4.70814492187298 3.9941916416683e-06 TRAPPC10 other 1.44088958545776e-14 0.0619379297873503 0.0230576746482131 4.84528727731235 -4.70814492187298 0.536992577600226 -44.1112910572397 59.8929067400002 -0.736502758978291 0.462059519153128 28.8311220203453 87.3544426922836 0.330047575506907 0.741618064718258 AIRE other 1 1 1 -0.736502758978291 0.330047575506907 1.9261156932618e-07 40.6112735974473 38.3567051372526 1.05877899189013 0.290639780021302 -237.395210493663 55.796196968063 -4.25468443000775 2.88305836378161e-05 C21orf2 other 0.00181112658637407 0.43842668538027 1 1.05877899189013 -4.25468443000775 0.000114716163256393 50.0569257275733 16.93404646853 2.9559931715434 0.00338892008309295 -28.7917010548385 24.5811549664815 -1.17129162946568 0.242502857910549 LRRC3 other 0.843622664587511 1 1 2.9559931715434 -1.17129162946568 0.360027393631662 -427.51566594577 307.134605127949 -1.39194886804654 0.165070821773286 -450.44958443024 445.831026757222 -1.01035943529236 0.313217762391174 ITGB2 other 1 1 1 -1.39194886804654 -1.01035943529236 3.97671751979664e-12 53.8244843548561 10.8980386306549 4.93891480650967 1.37323287464547e-06 -36.4993430138408 15.7748425753082 -2.3137690813455 0.0214260177982628 FAM207A other 4.78717255033119e-08 1 0.0150808434293565 4.93891480650967 -2.3137690813455 5.13324250854461e-11 285.568324569288 98.7493587789784 2.89184991275184 0.00414035164697738 -926.156848603582 187.300638677038 -4.94476076080311 1.3385807448106e-06 RALGDS other 5.91862861235193e-07 0.0209059540724519 1 2.89184991275184 -4.94476076080311 0.114366494304023 -5.10517325115978 13.6193673625775 -0.374846578056736 0.708068831575302 -40.4963602462975 20.668614970602 -1.95931659203568 0.0511045988719156 FTCD other 1 1 1 -0.374846578056736 -1.95931659203568 4.33125157801322e-05 55.3607208052114 15.9928572603723 3.46159037774858 0.000624089805632926 -19.1744792975058 24.2705993747329 -0.790029080100409 0.430204079220222 SPATC1L other 0.333852871633259 1 1 3.46159037774858 -0.790029080100409 2.18730278820354e-09 547.674672343264 117.251273462309 4.67094860610889 4.73284463106117e-06 -275.110487798094 178.60773132323 -1.54030559461181 0.124657013163736 LSS other 2.3211657188416e-05 1 0.0498936481006469 4.67094860610889 -1.54030559461181 0.000311266796762825 319.533494730004 82.2721531759631 3.88385963409257 0.000129048920045417 56.1142092055143 155.125458294216 0.361734365348892 0.717830362755496 VAV2 other 1 1 1 3.88385963409257 0.361734365348892 8.17531362603787e-20 477.812238083311 75.2523414131345 6.34946672901681 9.10982323972772e-10 -409.158171244122 114.631164162849 -3.56934498774571 0.000423435603378183 MCM3AP essential 1.19236949235762e-15 1 1.17881112722077e-05 6.34946672901681 -3.56934498774571 2.9166926480899e-05 53.1450222774083 20.1759737052187 2.6340747194601 0.00892544772491369 -59.8826901071076 30.7030958399403 -1.95037954541408 0.0521693844100815 C21orf58 other 0.228814538242653 1 1 2.6340747194601 -1.95037954541408 3.22384303555611e-12 200.869226649006 52.5756725480534 3.82057360208592 0.000165925296368572 -298.496624138828 78.9498300969473 -3.78083934787809 0.000193168365946516 PCNT other 3.89536953986245e-08 1 1 3.82057360208592 -3.78083934787809 1.26906394861201e-10 167.713732088731 50.1155358115107 3.34654173347599 0.000936306388081026 -275.218206569558 75.1320713575615 -3.66312550148878 0.000300620696321023 DIP2A other 1.43619967064421e-06 1 1 3.34654173347599 -3.66312550148878 0.218650710208591 -27.3623811665947 17.0250297893963 -1.60718550892856 0.109204486329947 -36.0125184652474 25.5654971991046 -1.4086375158199 0.1601145825499 S100B other 1 1 1 -1.60718550892856 -1.4086375158199 7.49150734027107e-12 239.681149937311 77.7240901284807 3.08374339977617 0.00226015497807107 -507.494888580124 116.713746352458 -4.34820151387796 1.95913210705305e-05 PRMT2 other 8.92613099593298e-08 0.299257429352353 1 3.08374339977617 -4.34820151387796 0.00697232514853884 3.0211992364639 1.11265611282484 2.71530367886409 0.00704686679782966 -1.17733529940513 2.44274444472515 -0.481972357750097 0.630214593097589 CLDND2 other 1 1 1 2.71530367886409 -0.481972357750097 0.287025504269793 16.8684209731411 11.9351552588134 1.41333904816066 0.158703638309301 -2.35288612977024 22.6497773709964 -0.103881203388037 0.917340459640355 ADAMTS13 other 1 1 1 1.41333904816066 -0.103881203388037 0.22508834308166 1.27332569086113 31.8403945399855 0.0399908892228729 0.968129726999106 -95.0691175930448 60.2284714030971 -1.57847468777293 0.115618825101268 CACFD1 other 1 1 1 0.0399908892228729 -1.57847468777293 0.567341102845415 18.1498953813406 26.9472755998218 0.673533593928903 0.501179792212783 -25.3729623101091 50.972773462875 -0.497774803809509 0.61904496579876 SLC2A6 other 1 1 1 0.673533593928903 -0.497774803809509 2.36836182694883e-09 78.5769008461461 16.9822030316089 4.62701456930478 5.75530240956469e-06 -106.870855806245 42.0481745710812 -2.54162890295233 0.0115912511296899 ZNF761 other 2.50833201092151e-05 1 0.0602465056233231 4.62701456930478 -2.54162890295233 0.578227421305317 1.9588368119126 6.8597837659648 0.285553725706556 0.775437281031657 -10.4860746979128 12.7170844685298 -0.824565939139753 0.410340564337212 C9orf116 other 1 1 1 0.285553725706556 -0.824565939139753 2.79887567661552e-09 72.6860294019288 15.4476953282672 4.70529926033193 4.06618892313167e-06 -65.9603509309556 34.564750590653 -1.90831265389754 0.0574192160731973 ZNF714 other 2.94945518801744e-05 1 0.0431178673408882 4.70529926033193 -1.90831265389754 0.0149370048627713 78.5370153115302 32.1245583666734 2.44476560315942 0.015129545575135 -33.3708300410496 60.5065131341329 -0.551524593180109 0.581726907464273 GPSM1 other 1 1 1 2.44476560315942 -0.551524593180109 2.96118834268097e-29 132.832977781491 11.2120471856516 11.8473438063552 2.35880395710114e-26 -116.55199776513 49.697136527249 -2.34524574069222 0.0197388088366109 C19orf47 other 4.62537619126768e-25 1 3.6964816811732e-22 11.8473438063552 -2.34524574069222 0.00728540122989715 24.9258113626129 15.2739841407285 1.63191287439847 0.103855011138061 -50.8204877667472 28.3065544201468 -1.79536113835799 0.0737061538553474 CFAP157 other 1 1 1 1.63191287439847 -1.79536113835799 1.50738926831945e-07 56.473700275076 14.1271393872188 3.99753260211824 8.25022750931203e-05 -55.927160686834 26.1811611286797 -2.13616044040039 0.0335590809171242 TOR2A other 0.00142659320353753 1 0.780801531481291 3.99753260211824 -2.13616044040039 0.106545116690042 55.2046848763014 65.0472891871248 0.848685403591398 0.396802641842729 -171.59198290981 121.094363925473 -1.41701048130874 0.157624216294847 ST6GALNAC6 other 1 1 1 0.848685403591398 -1.41701048130874 4.46828868799352e-27 396.244700870337 37.9816122382678 10.4325403141025 1.18323348928548e-21 -591.576017354486 160.016441568991 -3.6969702085234 0.000263868159003412 SHKBP1 other 6.91646406014517e-23 1 1.82525598057178e-17 10.4325403141025 -3.6969702085234 2.80646101167206e-07 80.817662465993 32.1929806583867 2.51041254376485 0.0126418843303207 -254.563050328906 71.6229700216935 -3.55420963765958 0.000447135275044058 RDH13 other 0.00261000874085501 1 1 2.51041254376485 -3.55420963765958 6.69629718428878e-16 245.856287933529 47.3942977372751 5.18746557436942 4.18046966719421e-07 -394.636488698631 88.3259963899043 -4.4679539980116 1.16103367216681e-05 ZER1 other 9.05540268231372e-12 0.17846248574876 0.00475528424643341 5.18746557436942 -4.4679539980116 3.28760650175158e-14 249.833285852549 49.766320080922 5.02012777810999 9.36857110289065e-07 -370.998140073971 92.7465964824118 -4.00012673396943 8.17269106960365e-05 ZDHHC12 other 4.25416281326655e-10 1 0.010413166780863 5.02012777810999 -4.00012673396943 2.96942466313677e-07 98.6268255732123 21.1465553445991 4.66396649317175 4.87617220375204e-06 -37.5806176526634 39.4096053786863 -0.953590306006665 0.341140846029113 PKN3 other 0.00275921159281644 1 0.0513509694777128 4.66396649317175 -0.953590306006665 0.368031232217851 4.23155987711815 2.98772904693337 1.41631312968673 0.15783648074184 4.25585536968693 12.657167164508 0.336240749163904 0.736950490616586 SPTBN4 other 1 1 1 1.41631312968673 0.336240749163904 0.392186818357957 17.2482207235207 12.6887693664367 1.35932967377785 0.175176376596125 20.6697629185315 28.1133640445581 0.735229084849863 0.462838133728616 BRSK1 other 1 1 1 1.35932967377785 0.735229084849863 0.00287610870533336 -8.25888760241227 36.867831566729 -0.224013381081664 0.82291693436319 -263.989234628491 81.7900129076358 -3.22764632555578 0.0014027959144934 COX6B2 other 1 1 1 -0.224013381081664 -3.22764632555578 0.464040550432262 -5.56165454314478 7.89485075204957 -0.704466077677394 0.481752001580828 11.0789949862529 17.5144541317888 0.632562962161887 0.527556393691913 TMEM190 other 1 1 1 -0.704466077677394 0.632562962161887 0.324735405040226 -4.74358418096923 3.87166418458987 -1.22520548136633 0.22155382104171 2.39512570321321 7.53251037249608 0.31797177630962 0.750749434324347 PLPP7 other 1 1 1 -1.22520548136633 0.31797177630962 1.12762779867879e-24 154.641953757275 16.4568110946452 9.39683592817042 2.35395733691385e-18 -95.9203520703795 32.1137899054003 -2.98688981751884 0.00307434192958878 MED27 other 1.72290251360133e-20 1 3.56648076115818e-14 9.39683592817042 -2.98688981751884 3.27077569394093e-12 204.600191842141 32.6128263138046 6.27361118209914 1.3964237813291e-09 -154.031538004772 88.6304236275246 -1.73790817758133 0.0833671312579548 DEDD2 other 3.95109703828065e-08 1 1.79566134041108e-05 6.27361118209914 -1.73790817758133 4.70124918008139e-10 164.077533642581 39.5269292055847 4.15103163691752 4.42752177444319e-05 -163.466396647801 68.5764135565681 -2.38371166075869 0.0178227882869007 SIK3 other 5.17325459776156e-06 1 0.430133740387156 4.15103163691752 -2.38371166075869 2.4156177163931e-09 25.1315809803394 27.4070983048008 0.916973431511981 0.359974885977034 -249.224448147677 49.0132162373339 -5.08484174841479 6.88855985035175e-07 MPZL3 other 2.5557235439439e-05 0.0108067726932318 1 0.916973431511981 -5.08484174841479 0.345908655542837 -72.0663602302132 52.0302517821329 -1.38508574842147 0.167169557063664 -103.015944444137 93.0477919668682 -1.10712938229441 0.269223359681827 JAML other 1 1 1 -1.38508574842147 -1.10712938229441 2.38110030756078e-09 43.8386307121442 8.22161967100623 5.33211611171244 2.1033713493482e-07 -21.4243131999371 18.5759795673828 -1.15333423587285 0.249828322372645 NEK8 other 2.5208708956146e-05 1 0.00243991076524392 5.33211611171244 -1.15333423587285 5.71088448562307e-15 119.912959276158 16.6612000568064 7.19713819336631 6.53449836177559e-12 -46.33209878456 37.6444209545189 -1.23078261292788 0.219512184093167 TLCD1 other 7.54350731705951e-11 1 9.0267560369568e-08 7.19713819336631 -1.23078261292788 0.0353728448473111 -268.082344291974 207.798176965925 -1.29010922139098 0.198104440432823 -936.993037562101 360.515071783083 -2.59903984853615 0.00985674553428451 PCSK7 other 1 1 1 -1.29010922139098 -2.59903984853615 2.76137425372383e-09 295.08800892594 97.6397280947567 3.02221252234096 0.00274763569650391 -601.344682167228 187.667601423845 -3.20430739032626 0.00151455375752664 SAFB other 2.91131687570103e-05 1 1 3.02221252234096 -3.20430739032626 0.252772836468571 -12.5083666284267 12.4163014029049 -1.00741486716007 0.314640767280174 13.6173899283991 22.0133019494803 0.618598243900459 0.536704511416846 CD3G other 1 1 1 -1.00741486716007 0.618598243900459 0.249467740567594 20.9246361037156 14.5618959439529 1.43694448746593 0.151878832154413 -38.5898546953489 49.5426451633407 -0.778921968500456 0.436700327836627 S100A1 other 1 1 1 1.43694448746593 -0.778921968500456 6.24504775977044e-09 375.02632873313 59.4700581219442 6.30613691286686 1.14694973893799e-09 -111.497062068367 202.329696539429 -0.551066224955461 0.58203897920064 CHTOP other 6.44613829763504e-05 1 1.47922107830833e-05 6.30613691286686 -0.551066224955461 1.59194817890693e-07 154.455688258339 61.9961129587506 2.49137697328068 0.0133211833681708 -351.829653819611 111.13204800309 -3.16587033300986 0.00172205545604797 CXCR5 other 0.00150327666534181 1 1 2.49137697328068 -3.16587033300986 0.289102165215991 84.3206641328266 58.2474983337511 1.44762722082379 0.148881450880175 -104.251078787186 195.047551816661 -0.534490578406126 0.593442008343229 ZBTB7B other 1 1 1 1.44762722082379 -0.534490578406126 4.5394547308511e-15 385.883563478205 44.9974722483296 8.5756720143881 7.79299472353138e-16 -86.1352036717071 152.074587130737 -0.566401035813155 0.571591682265908 FLAD1 other 6.01840908216239e-11 1 1.151492900349e-11 8.5756720143881 -0.566401035813155 0.0060549192405353 774.762097671456 242.635433098676 3.19311193660809 0.00157354444944633 -203.860459551483 819.866633756352 -0.248650757523163 0.803819271818834 SHC1 other 1 1 1 3.19311193660809 -0.248650757523163 1.98256565179851e-13 163.245085290293 33.9409854436809 4.80967429661608 2.51131696389245e-06 -186.655392976437 61.0024968937916 -3.05979922922521 0.00243692037904508 VPS11 other 2.50398041822151e-09 1 0.0270519063350494 4.80967429661608 -3.05979922922521 2.82166467647472e-10 59.1799892909048 38.0631345267714 1.55478496520777 0.121164319773921 -338.761398447546 68.4112796191556 -4.95183543318331 1.29471384600092e-06 NLRX1 other 3.14023061844872e-06 0.0202273144160723 1 1.55478496520777 -4.95183543318331 3.02998909449209e-09 1987.24295235468 308.135405436901 6.44925223551313 5.0873914770573e-10 -342.012008783819 1045.27162092195 -0.327199171907259 0.743767994160836 ADAR other 3.18512453613009e-05 1 6.6410808341506e-06 6.44925223551313 -0.327199171907259 0.552568000935817 58.8745472356809 55.7860843854224 1.05536260313451 0.292192587131869 -42.581400862943 191.400182160922 -0.222473147006423 0.82411192418418 IL6R other 1 1 1 1.05536260313451 -0.222473147006423 1.36890650106512e-14 447.251289266873 54.86838218384 8.15134821668934 1.31104921036707e-14 -365.639008395444 188.251576724864 -1.94228922145942 0.0531304260376384 UBE2Q1 other 1.78820256234137e-10 1 1.9069210764789e-10 8.15134821668934 -1.94228922145942 0.681709989820618 9.81076557337669 11.3253417441002 0.866266625330531 0.387104644278925 -3.41712346075731 38.8568672050753 -0.0879413011533514 0.929987802877702 CHRNB2 other 1 1 1 0.866266625330531 -0.0879413011533514 5.48126539434896e-08 216.280738298741 37.4558942777254 5.77427778643001 2.09859437613753e-08 -153.98792975765 128.604063111805 -1.19737997409753 0.232197121419095 CRTC2 other 0.000533491560831984 1 0.000256406260876484 5.77427778643001 -1.19737997409753 5.40864292473611e-07 101.639866982534 26.0417201984036 3.90296286912585 0.000119868815620861 -163.291705537 68.413628448198 -2.38683006940119 0.0176779990487921 ANO10 other 0.00492294679009481 1 1 3.90296286912585 -2.38683006940119 1.95199708729484e-16 1235.19252168324 137.20120866808 9.00278163490126 4.1243469476824e-17 -371.024002863275 459.515772546199 -0.807423868842221 0.420135687758293 FDPS essential 2.6746264090114e-12 1 6.17950903171254e-13 9.00278163490126 -0.807423868842221 4.76318702481748e-06 258.884509111551 51.6354533544334 5.01369683605816 9.70001076121409e-07 -68.1435559673777 172.938019054463 -0.394034558392376 0.693867700059043 RUSC1 other 0.0400822188138391 1 0.0107689519470999 5.01369683605816 -0.394034558392376 5.72965238242801e-06 86.2942304642175 17.7970326133868 4.84879880476858 2.10357191014817e-06 -59.6773757648611 59.6060141871988 -1.00119722109648 0.317631227309115 GBAP1 other 0.0478597863504211 1 0.0227837873588148 4.84879880476858 -1.00119722109648 1.1278999414014e-07 270.777032046949 46.5965993237173 5.81108999319453 1.75086936105064e-08 -11.6038583222731 156.061834615931 -0.0743542349789125 0.940783784798523 FAM189B other 0.00107691886405006 1 0.000214866687988135 5.81108999319453 -0.0743542349789125 0.186429963297681 14.6090914230791 9.11827119057982 1.60217777227024 0.110276948758087 -22.9141742522757 30.0813651792076 -0.761739838460328 0.446875257171887 PAQR6 other 1 1 1 1.60217777227024 -0.761739838460328 9.34250166577988e-14 257.451715949568 32.0401013151526 8.03529656218072 2.85870506984754e-14 -96.3374078890336 105.700956672098 -0.911414720567651 0.362883923838126 PMF1 essential 1.19238348760349e-09 1 4.13654623606939e-10 8.03529656218072 -0.911414720567651 1.46036811204089e-11 212.413863289422 29.0044706742666 7.32348697809127 2.74427359167264e-12 -41.807932379714 95.6863484257428 -0.436926824646872 0.662511080484509 SLC25A44 other 1.72235815134103e-07 1 3.82905044285141e-08 7.32348697809127 -0.436926824646872 0.0993419481153269 937.809464578505 472.682803845909 1.98401434735549 0.0482592904011431 -1055.60468140443 1559.39034266828 -0.676934217508476 0.499022980423208 LMNA other 1 1 1 1.98401434735549 -0.676934217508476 0.118023085297688 -56.0750036124556 27.1792806276178 -2.06315260439512 0.0400435928279713 -34.3495050935622 70.6428956579309 -0.486241465240756 0.627186056587876 CCR5 other 1 1 1 -2.06315260439512 -0.486241465240756 0.63487315111584 -76.4295243346486 153.529419643737 -0.497816799620569 0.619015401716894 -367.330968678983 397.50005537459 -0.924102937124936 0.356251791238991 NBEAL2 other 1 1 1 -0.497816799620569 -0.924102937124936 3.42665126722564e-08 106.80329264317 28.6156166856964 3.73234286076231 0.000230828479955489 -238.678010407988 74.3240983076461 -3.21131390548513 0.00147942651858694 CCDC12 other 0.000337765015410432 1 1 3.73234286076231 -3.21131390548513 0.813871902172467 -5.80408954250733 9.07665626678277 -0.639452389945421 0.523064881393623 -6.40468600958681 23.5750394648766 -0.271672334594768 0.786079304470902 PTH1R other 1 1 1 -0.639452389945421 -0.271672334594768 7.75127126012503e-12 328.820378001989 44.382717732132 7.4087481525254 1.61069109480137e-12 -77.215319027995 146.062143010221 -0.528647036368567 0.597481412800778 UBQLN4 other 9.22866356230486e-08 1 2.25867212223996e-08 7.4087481525254 -0.528647036368567 4.92134132293019e-14 111.42818612636 14.4601993290899 7.70585408889885 2.44106333418423e-13 -80.5146374187779 63.8294902306222 -1.26140185559795 0.208244831304657 PPP1R35 other 6.33573481914032e-10 1 3.48364148421431e-09 7.70585408889885 -1.26140185559795 7.23617436603939e-09 209.292252818392 33.9183784819398 6.1704675219021 2.44952310003005e-09 -116.299783073299 111.331352278786 -1.04462741799877 0.297119291552197 GPATCH4 other 7.43516916110547e-05 1 3.11873281095826e-05 6.1704675219021 -1.04462741799877 0.0237468242538217 -2.02488613338413 4.21230218359066 -0.48070770925985 0.631110668501774 36.1842261647052 13.5436875387978 2.67166722955254 0.00800280760954425 LRRC71 other 1 1 1 -0.48070770925985 2.67166722955254 0.711479843018656 6.30783076912646 9.41542039291643 0.669946800662462 0.503462145798231 16.2732151870284 30.674924721361 0.530505464474579 0.596195960160843 FCRL3 other 1 1 1 0.669946800662462 0.530505464474579 0.816182925999211 178.088291581591 285.672896148063 0.623399328332811 0.533546454635677 333.889770001891 1292.9162299636 0.258245478139981 0.796413476226624 AZGP1 other 1 1 1 0.623399328332811 0.258245478139981 0.00223805778734844 214.226531226041 73.3734872884704 2.91967220235562 0.00379626506422301 -53.5480706911962 122.917044244871 -0.435643982656462 0.663439303374607 FGFR4 other 1 1 1 2.91967220235562 -0.435643982656462 1.51390758416113e-13 359.229926162187 90.6781062716004 3.9615949310434 9.53329423476355e-05 -896.427293346652 201.085584185127 -4.45793912566784 1.21434620662686e-05 NACC1 other 1.91902925368265e-09 0.186560007724084 0.896320323952469 3.9615949310434 -4.45793912566784 0.768967139045799 -1.40693753797151 41.3107538452964 -0.0340574162175862 0.97285625317417 -45.2479103020737 68.7656840346611 -0.658001311806434 0.511091752566519 HK3 other 1 1 1 -0.0340574162175862 -0.658001311806434 1.08809307869691e-05 279.311899491457 57.4926846822028 4.85821632848395 2.00254570414147e-06 166.856526950398 214.995334710519 0.776093710010326 0.438367958754101 LY6K other 0.0888319189448157 1 0.0217436412555681 4.85821632848395 0.776093710010326 0.0050417064204039 400.898264369212 156.039331468216 2.56921290675276 0.0107324837395604 -217.310214612374 347.156879082584 -0.62597121850689 0.531864582845527 IER2 other 1 1 1 2.56921290675276 -0.62597121850689 1.2371523564794e-29 103.15164781195 8.62975816172378 11.953017208462 1.06999856013388e-26 -116.424248069367 39.1794276217145 -2.97156582259107 0.00323087098399824 ZNF394 other 1.93552486171202e-25 1 1.67839974142601e-22 11.953017208462 -2.97156582259107 1.31930519520918e-27 275.086332334709 22.5471321084081 12.2005020865658 1.58739648432863e-27 -62.8348225665422 103.784037951418 -0.605438213879821 0.545400216937951 CPSF4 essential 2.0472978019256e-23 1 2.49364113723185e-23 12.2005020865658 -0.605438213879821 0.00112992178148601 1427.65871885758 384.429173400989 3.71371065891615 0.000247964620953799 1867.41178618408 1437.94773245083 1.29866457871961 0.195163022580197 LY6E other 1 1 1 3.71371065891615 1.29866457871961 2.42705893730539e-09 364.900581866235 58.0957377534586 6.28102156848007 1.3586949027378e-09 -20.3584800431958 222.762086361477 -0.0913911356089564 0.927250332714103 VPS28 essential 2.56758564977537e-05 1 1.74782512288191e-05 6.28102156848007 -0.0913911356089564 4.25972167470917e-06 179.848134806364 36.4524572210214 4.93377260457078 1.42361388295309e-06 13.2581230509206 138.209381755503 0.0959278081018743 0.923650138569402 TONSL essential 0.0360202064813407 1 0.0156184679098783 4.93377260457078 0.0959278081018743 7.37614860589446e-05 40.0377669779315 41.9279791325189 0.954917642259525 0.340470361132505 -226.837344787157 73.0028993008401 -3.10723747905375 0.00208918684200224 MUM1 other 0.554833898135382 1 1 0.954917642259525 -3.10723747905375 5.41013113627857e-06 229.451568234525 48.7791141119186 4.70388961365867 4.11301883089658e-06 -91.4251311211772 182.811202270542 -0.500106831450499 0.617414886376059 RECQL4 ts 0.0453152583974693 1 0.0435733214945184 4.70388961365867 -0.500106831450499 1.07304914555963e-08 143.442640668272 26.1698480681358 5.48121793809446 9.83499416333744e-08 -146.519475938317 98.0776604018805 -1.49391283741825 0.136388121429573 LRRC14 other 0.00010913982859487 1 0.00116328310963955 5.48121793809446 -1.49391283741825 1.85135627255726e-15 97.402257459276 12.0817500082079 8.06193286511509 2.39801774399321e-14 5.15653641226586 29.9187183649081 0.17235151417161 0.863289357064306 ZNF333 other 2.47692955705436e-11 1 3.47424810749737e-10 8.06193286511509 0.17235151417161 9.18447152729849e-05 203.425963088109 46.3829049656227 4.38579608670222 1.65576533829548e-05 200.759399792619 192.778829407867 1.0413975456188 0.298619238534108 COL26A1 other 0.684059439353192 1 0.166934261406951 4.38579608670222 1.0413975456188 3.39437112813331e-08 173.738894017517 31.9439938437909 5.43885948848839 1.21869306610914e-07 -136.41207529327 119.717629691011 -1.13944851435287 0.255545033442185 PPP1R16A other 0.000334617105811382 1 0.00143391426158401 5.43885948848839 -1.13944851435287 0.0135004650304157 70.4398712088802 26.0061969881609 2.70858023727757 0.00719720950226071 -41.9685145422203 97.4643394913278 -0.430603795821698 0.667106491109576 FOXH1 other 1 1 1 2.70858023727757 -0.430603795821698 0.00160710326695378 118.021559544049 36.6382840834645 3.22126329047473 0.00143382211828801 -117.105167672665 149.054367410386 -0.785654051653808 0.432764226804607 ORAI2 other 1 1 1 3.22126329047473 -0.785654051653808 2.50286473982191e-20 67.5302122674699 7.62055118214479 8.8615915900802 1.12113048672609e-16 -89.7802151200162 31.0024463259648 -2.89590744472395 0.00409232081881862 ALKBH4 other 3.6737048651106e-16 1 1.67339936448736e-12 8.8615915900802 -2.89590744472395 3.05217060425459e-05 23.2176530771366 5.86271722616355 3.96022052258007 9.60232140074749e-05 -31.7546220756648 23.8511062761853 -1.3313689397867 0.184199004739736 SH2B2 other 0.238862871488964 1 0.902426165242249 3.96022052258007 -1.3313689397867 7.29751251120899e-08 1877.56184020569 522.236789178904 3.59523089738224 0.000384745311334144 -2266.0897123105 857.807175904452 -2.64172389315954 0.00872605719980853 MRNIP other 0.000704866733457676 1 1 3.59523089738224 -2.64172389315954 3.8803232942812e-07 3757.94004375973 1035.56472901127 3.62887991303807 0.000339942134619293 -3785.53322828046 1700.9809995502 -2.22550000810208 0.0268676411857979 SQSTM1 other 0.00357416578636241 1 1 3.62887991303807 -2.22550000810208 8.4688364180644e-09 603.613620029038 152.176290714377 3.96654181275829 9.33192988457968e-05 -668.607096189114 249.959246231112 -2.67486442798328 0.00792886321182329 MGAT4B other 8.66785407388891e-05 1 0.877947963541256 3.96654181275829 -2.67486442798328 2.34053489328511e-08 286.201110111154 53.7010631824129 5.32952409413162 2.06920797419497e-07 -33.3045327924834 88.2074153067595 -0.377570668822571 0.706044004296497 MAML1 other 0.000233164086069062 1 0.00240110893325584 5.32952409413162 -0.377570668822571 0.474921973447101 0.40601545804697 4.63153350050526 0.0876632886284158 0.930209764470615 -21.478385036262 18.6251609517736 -1.15319191559613 0.249859086456562 FBXL13 other 1 1 1 0.0876632886284158 -1.15319191559613 1.20037282387873e-12 66.4487340437281 10.4083595947969 6.38416970883153 7.52117569710713e-10 -111.502120388876 41.2766634421753 -2.70133559959564 0.0073447925466461 NAPEPLD other 1.47465801413502e-08 1 9.76098181970564e-06 6.38416970883153 -2.70133559959564 0.531524626419752 82.4084922673363 274.144845371021 0.300602012617844 0.763947630962333 -379.749767746875 450.300362726682 -0.843325476016484 0.399787442971087 SCGB3A1 other 1 1 1 0.300602012617844 -0.843325476016484 2.11935417078921e-18 532.861894766442 60.0115547331878 8.87932160957258 9.75901259919635e-17 -384.229990320783 237.98915907957 -1.61448526397927 0.107594541389365 PSMC2 essential 3.02410646629912e-14 1 1.45731335143799e-12 8.87932160957258 -1.61448526397927 3.20381022815337e-05 181.977301306244 62.8341574108176 2.89615248783323 0.00408570834641102 -136.841374232983 105.830557615671 -1.29302327528056 0.197104207143911 MFSD12 other 0.250281655023341 1 1 2.89615248783323 -1.29302327528056 0.811187507999902 2.87401707256716 4.56288638571388 0.629868208326538 0.529353762009506 6.14245722048846 19.2948673751317 0.318346692986612 0.750486690059931 USP41 other 1 1 1 0.629868208326538 0.318346692986612 4.04307984655504e-21 18.3846873529222 1.72151260234311 10.679380056759 4.02238492441231e-22 17.4782371793042 7.33301027348889 2.38350098083095 0.0179083893607217 TUBA3FP other 5.99386587251784e-17 1 6.21780261615655e-18 10.679380056759 2.38350098083095 5.77196057943282e-22 337.164754210901 32.0948807850635 10.5052502443883 8.04670859087548e-22 39.6148586055777 111.358118788842 0.355742886431979 0.722315078957241 YDJC other 8.63543022288945e-18 1 1.24225087225936e-17 10.5052502443883 0.355742886431979 7.18861448723861e-50 1562.70762489541 82.8752105280365 18.8561527016182 4.62528441545567e-51 535.203050158045 986.755751268122 0.542386552569096 0.58800296186364 DVL3 other 1.14442742636839e-45 1 7.36669048849625e-47 18.8561527016182 0.542386552569096 1.85856989704558e-22 1963.37829460765 178.25526073052 11.0144199198464 1.6088599816393e-23 679.426640689765 2122.4006865133 0.320121758821108 0.749125466639594 AP2M1 essential 2.79324469826981e-18 1 2.50322524543259e-19 11.0144199198464 0.320121758821108 1.50638881227674e-38 460.007736155176 29.4851048268549 15.6013600377708 1.90643132570067e-39 598.409728256633 327.264066195949 1.82852256042781 0.0685867230943659 ABCF3 other 2.38777690633987e-34 1 3.02855680400808e-35 15.6013600377708 1.82852256042781 2.18499187872187e-25 796.351844071229 66.9824807226843 11.8889571643102 1.91619705016448e-26 439.758947927817 516.877174805834 0.850799705158219 0.395642974163461 PCYT1A essential 3.35396253383807e-21 1 3.00383049583784e-22 11.8889571643102 0.850799705158219 4.36845782973913e-29 432.768133213276 34.5442141978758 12.5279484064769 1.18553337822409e-28 -180.975932576537 191.763985448719 -0.943743071218831 0.346150957891907 FBXO27 other 6.82003636378873e-25 1 1.86543677063561e-24 12.5279484064769 -0.943743071218831 0.172959998852732 152.477583028182 214.569484015742 0.710621008050685 0.477934767910378 -1275.97200230123 838.386903808114 -1.52193694403565 0.129199503065217 DMKN other 1 1 1 0.710621008050685 -1.52193694403565 6.98950230521127e-17 81.9938751732932 9.36227720776787 8.75789867717899 2.26277703764675e-16 -29.7537505570133 37.4568614672855 -0.794347134049124 0.427693589430328 U2AF1L4 other 9.68675124479231e-13 1 3.36836989824095e-12 8.75789867717899 -0.794347134049124 1.03618518595781e-12 233.905241898389 29.8760740523977 7.82918269275133 1.26049724178028e-13 77.8650953379083 216.110246549016 0.360302653767265 0.718914467094505 BDH1 other 1.27626929354424e-08 1 1.80604044802279e-09 7.82918269275133 0.360302653767265 7.97844866356088e-09 31.3513535746335 5.35090844375098 5.85907120336679 1.35624133477857e-08 -20.3823148334945 22.123954813375 -0.921278089990148 0.357730747912682 THAP8 other 8.17950556988261e-05 1 0.000167373743125024 5.85907120336679 -0.921278089990148 0.36922095832423 4.29972202918697 7.66421130190038 0.561012980960067 0.575252257204438 43.2604597292478 31.027285461513 1.39427149638692 0.164377652704255 COX7A1 other 1 1 1 0.561012980960067 1.39427149638692 3.29771490166603e-05 15.1382636169859 3.26960558974036 4.62999686093269 5.69674292296131e-06 16.2068568246386 13.4370485293714 1.20613219407616 0.22882626499175 ZNF382 other 0.257221762329951 1 0.0596562918892508 4.62999686093269 1.20613219407616 0.180606630287514 -0.763833220856231 10.4428956077746 -0.0731438146607121 0.941745237123528 -24.126131862328 16.8356080186556 -1.43304190948101 0.152990025551327 LRRC56 other 1 1 1 -0.0731438146607121 -1.43304190948101 0.53002870704358 -27.6137949052906 32.0996604729503 -0.860251930968558 0.39043368999278 -65.1276409442939 61.6345395144412 -1.05667441433604 0.291629846431274 PLXDC1 other 1 1 1 -0.860251930968558 -1.05667441433604 2.66228390637762e-05 99.962656711574 36.5235403476201 2.73693776014481 0.00662421306098397 -154.598301460173 71.0114643409011 -2.17708933191409 0.0303632633857844 PGAP3 other 0.209734726144429 1 1 2.73693776014481 -2.17708933191409 0.28652490743632 -47.0821417010224 40.887466754859 -1.15150547191646 0.250570079933338 -121.281239047907 81.4283074250232 -1.48942355408258 0.137574060290373 IKZF3 other 1 1 1 -1.15150547191646 -1.48942355408258 0.13153821425916 16.7684493858575 9.20472182167536 1.82172255834728 0.0695913089547983 -8.41373745248847 20.7553236660706 -0.405377318506609 0.68551767848902 GRIN2C other 1 1 1 1.82172255834728 -0.405377318506609 1.50779810357478e-06 183.072317790044 35.8805565321311 5.10227085318764 6.2927185546128e-07 -13.9145340281499 80.9054937857512 -0.171985033117745 0.863576716434443 FDXR essential 0.013236959551283 1 0.0070711278398184 5.10227085318764 -0.171985033117745 2.19761209061228e-15 291.615440161973 33.4818479237512 8.70965786673644 3.06462757516326e-16 99.3875077642678 77.5414742647256 1.28173353301177 0.201031646983636 SAP30BP essential 2.93513070822176e-11 1 4.55311718842006e-12 8.70965786673644 1.28173353301177 5.21593657254176e-06 243.830147541307 50.1045198654022 4.86643017828167 1.93109150449048e-06 -24.7464736790732 115.070366628995 -0.215055138903483 0.829886079634717 ACOX1 other 0.0437460600339078 1 0.020996757928325 4.86643017828167 -0.215055138903483 2.55403552702992e-13 303.442524680908 42.8709642486664 7.07804291316697 1.25331317708261e-11 -184.25931313804 95.40806363897 -1.93127610088901 0.0544916848477863 PRPSAP1 other 3.21425371076715e-09 1 1.71992167291046e-07 7.07804291316697 -1.93127610088901 0.956943949281563 -0.0253542857990521 21.7139009897636 -0.00116765227081972 0.999069207552066 13.8710386504088 48.323644774239 0.287044545485182 0.774297563390117 CYGB other 1 1 1 -0.00116765227081972 0.287044545485182 0.0935530635794261 7.39650560107006 4.09720782647139 1.80525516750272 0.0721364042982291 -4.46228962520749 9.56367766142852 -0.466587204544173 0.641167359324297 ZNF577 other 1 1 1 1.80525516750272 -0.466587204544173 1.11636235035193e-05 23.8048463569126 6.23565823029818 3.8175354513896 0.000166958555021257 -14.9905224139177 12.9864658160376 -1.15431885982445 0.249382639633004 TMEM143 other 0.0910058588006894 1 1 3.8175354513896 -1.15431885982445 1.28453246777141e-10 71.8868841841743 47.8132148573585 1.50349405281856 0.133871856153614 -564.673443960504 99.2752079678 -5.68796032281953 3.3158193933538e-08 ALDH16A1 other 1.45332003403658e-06 0.000525623690234444 1 1.50349405281856 -5.68796032281953 0.296199169470858 30.6148491082667 285.851906531129 0.107100384530522 0.914788004933723 1167.88317835528 773.328154992092 1.51020387763746 0.13214795220701 ITGA5 other 1 1 1 0.107100384530522 1.51020387763746 0.597326973407766 -5.81494524335819 5.75001432791716 -1.01129230498188 0.312775300817168 -5.69016498432523 11.8710527741091 -0.479331116843784 0.632088240554059 SIGLEC11 other 1 1 1 -1.01129230498188 -0.479331116843784 0.00965201042486051 96.4988194004072 129.871784500885 0.743031442674524 0.458101556011692 -906.240601229107 351.348041412005 -2.57932447150435 0.0104229572825985 ZNF385A other 1 1 1 0.743031442674524 -2.57932447150435 0.644766352768755 -0.471058404283046 3.23776733410362 -0.145488651800689 0.884432829914359 -6.0912545700574 6.68445410767408 -0.911256846398922 0.362966931233843 SIGLEC16 other 1 1 1 -0.145488651800689 -0.911256846398922 0.000197158781003849 60.7068253749829 18.562178129861 3.27045807610928 0.0012126686828263 -41.5308844777763 37.8643350836025 -1.09683385132944 0.273687705969098 MPP3 other 1 1 1 3.27045807610928 -1.09683385132944 0.910087213478221 3.49732523737445 8.8160876287207 0.396698102906896 0.691902305765691 5.76829331223337 17.9836274474316 0.320752491625775 0.748645166346987 CD300LG other 1 1 1 0.396698102906896 0.320752491625775 0.0849152708126686 14.2416998146846 6.7494135997478 2.1100647640288 0.0357693988882831 2.70795509681506 13.7809858843259 0.196499373814396 0.844366599390642 NAGS other 1 1 1 2.1100647640288 0.196499373814396 2.72828889867405e-10 114.849222177902 24.74266371883 4.64174849899036 5.38786938731099e-06 -141.936989987357 51.3134906675782 -2.7660755123221 0.00606367916064358 LSM12 essential 3.03904100423303e-06 1 0.0565672406973781 4.64174849899036 -2.7660755123221 2.22127510073015e-05 10.6439325279243 3.88600508523865 2.73904235698411 0.00656900177735472 -19.875354362666 8.03864215320899 -2.47247656803977 0.0140299195737427 ASB16 other 0.176546945006032 1 1 2.73904235698411 -2.47247656803977 3.16232930417505e-11 864.231986458544 169.259831297301 5.10594852797968 6.20916473434802e-07 -1045.57695087545 362.796468517373 -2.88199318793914 0.00426805556289398 EMC10 other 3.67715651489475e-07 1 0.00698034299435404 5.10594852797968 -2.88199318793914 0.000100047239361713 11.9848607264271 21.0944586190788 0.568152088794898 0.570402145729179 -171.682212063407 45.2144790268951 -3.79706270553918 0.000180735865054008 JOSD2 other 0.741650185388381 1 1 0.568152088794898 -3.79706270553918 0.647201923779114 3.39632447107603 3.64174529602122 0.932609008869092 0.351852015216326 2.57257949650352 7.946985393823 0.323717657579077 0.746401481593989 SHANK1 other 1 1 1 0.932609008869092 0.323717657579077 0.034640093181899 28.3570648243368 11.1667753368368 2.53941392827999 0.0116610710782741 10.1179062621109 23.0997409856961 0.438009511378338 0.661727022316751 FAM171A2 other 1 1 1 2.53941392827999 0.438009511378338 2.27167838287843e-10 76.6458697158164 14.0994481950927 5.43609002673542 1.21172732672412e-07 -58.1185325537333 29.5134628646131 -1.96922105753364 0.0499425747384947 DBF4B other 2.54109943908782e-06 1 0.00142583954535627 5.43609002673542 -1.96922105753364 0.97797269242754 -13.5181117494207 76.0521597322754 -0.177747900874981 0.85905278006718 6.13321839854935 159.783080861016 0.0383846547800903 0.969409049660283 PLCD3 other 1 1 1 -0.177747900874981 0.0383846547800903 0.218656763842685 67.6478473605892 69.986385175412 0.966585817956427 0.334606611366617 -184.939187463745 178.661104584582 -1.03513961751082 0.301519766968137 FMNL3 other 1 1 1 0.966585817956427 -1.03513961751082 0.382407423742939 2.24339832026026 34.4365847275878 0.0651457842874596 0.948105605568787 116.483950572524 87.909644856367 1.32504176035341 0.186265248168095 AQP5 other 1 1 1 0.0651457842874596 1.32504176035341 9.00457957138441e-09 443.2190597493 74.7374796591556 5.93034528018104 9.11561508511148e-09 9.07013654190527 190.789689113184 0.0475399723332244 0.962117631908996 RACGAP1 essential 9.20268032195486e-05 1 0.000113398251658787 5.93034528018104 0.0475399723332244 1.58735706777904e-10 228.493454931071 44.7435094455662 5.10673967604285 6.17192532771305e-07 -301.328907741251 113.236962435896 -2.66104725223298 0.00825290243709261 LARP4 other 1.78768152973275e-06 1 0.00693971283848055 5.10673967604285 -2.66104725223298 0.291886451242891 62.7809487368532 45.374901725865 1.38360517266016 0.167609656298466 -24.2257986243967 117.142486717261 -0.20680625196961 0.836315334855853 GRASP other 1 1 1 1.38360517266016 -0.20680625196961 4.27956562511966e-19 436.433939152149 73.236883900422 5.95920956639219 7.82886919436886e-09 -669.565436852135 155.950064986978 -4.293460454204 2.44939416054047e-05 RAVER1 other 6.1762691101727e-15 0.373140706416735 9.76338277229741e-05 5.95920956639219 -4.293460454204 0.0614280701739823 14.2224588041317 6.64896094158912 2.13904983486525 0.0333220801543866 -4.73565776918712 17.9128295711752 -0.264372401376921 0.791693182715374 KRT84 other 1 1 1 2.13904983486525 -0.264372401376921 7.04172912243224e-06 9.40379826107216 2.21565625880412 4.24424963200194 3.01853664852447e-05 -1.78284956963725 4.94919880628882 -0.360229936080125 0.718956821770682 SYCE2 other 0.0583688926958409 1 0.297869196476394 4.24424963200194 -0.360229936080125 1.16141991881036e-15 157.565851940759 22.7321127105747 6.93142137498999 3.04143139518602e-11 -65.5398694139168 44.1721451801346 -1.48373752614106 0.139040658314987 SPC24 essential 1.56210979079993e-11 1 4.12600583070936e-07 6.93142137498999 -1.48373752614106 0.891572646169802 4.27674780546093 10.1545301696358 0.421166487667673 0.673967348130487 -0.398510163501554 18.7045048159378 -0.0213055714344274 0.983017577865301 IP6K3 other 1 1 1 0.421166487667673 -0.0213055714344274 1.27408328336751e-14 346.2387914273 52.4058770222971 6.60686951732504 2.07083468167137e-10 -184.585991858617 96.5309042143657 -1.91219582330554 0.0569053540247912 LEMD2 other 1.66586389300303e-10 1 2.74033553425573e-06 6.60686951732504 -1.91219582330554 0.442780522649855 -337.739227511029 282.162912962299 -1.19696534163636 0.232362245593966 75.8730832795201 844.213838942349 0.0898742472340607 0.928453289166568 ALOX15 other 1 1 1 -1.19696534163636 0.0898742472340607 0.0439042713870117 16.3946760780191 6.54638437442762 2.50438641245422 0.0128498550964929 9.80649553260461 13.6991939952957 0.715844708526078 0.474699073938658 ADCY10P1 other 1 1 1 2.50438641245422 0.715844708526078 2.54934675874631e-09 15.3407698509232 4.42432816599171 3.46736708385296 0.000610731603072919 -30.7446725542857 9.43305663626816 -3.25924816735212 0.00125917105822096 ZNF653 other 2.69236511191198e-05 1 1 3.46736708385296 -3.25924816735212 1.30832683062409e-09 46.6411525147832 8.89638759589585 5.24270688659069 3.1811010464512e-07 -64.4574179856067 26.6174368778714 -2.42162377547305 0.0161056454585276 MED11 essential 1.40501218340721e-05 1 0.0036493126059626 5.24270688659069 -2.42162377547305 0.707042451289435 -100.088991748564 149.505366365595 -0.669467552782084 0.503765142363708 -297.890786110365 447.310732501706 -0.665959397943194 0.506001441719513 CXCL16 other 1 1 1 -0.669467552782084 -0.665959397943194 0.0555434679108744 -39.7921805520598 16.4703031898936 -2.41599563124478 0.0163488591906576 -37.0906809369037 51.1379556837935 -0.72530629042448 0.468885400164358 SCIMP other 1 1 1 -2.41599563124478 -0.72530629042448 3.2103600865844e-08 514.543577155209 99.5892798091345 5.16665627205403 4.60568046183007e-07 -497.842333044809 298.34823950892 -1.66866187601527 0.09633081710207 RNASEK-C17orf49 other 0.000317183576554539 1 0.00522145993957675 5.16665627205403 -1.66866187601527 0.528032047345362 -29.5114404107737 28.9332852500592 -1.01998235443081 0.308639859755687 -64.6772088687659 86.6779510215196 -0.746178331473346 0.456201742976577 BCL6B other 1 1 1 -1.01998235443081 -0.746178331473346 0.0364039276946951 -3.26156384408869 1.37241284535711 -2.37651800995786 0.0181692926611406 -6.69278198512168 4.10617364496632 -1.62993155277937 0.104273416421731 ASGR2 other 1 1 1 -2.37651800995786 -1.62993155277937 0.228313406079368 -157.212054143466 98.3626661913085 -1.5982898820341 0.111135204601605 -308.421600889965 286.335748764622 -1.07713270948748 0.282371872074104 TNFSF13 other 1 1 1 -1.5982898820341 -1.07713270948748 6.22827237311876e-34 2678.9970878084 196.360808257954 13.6432372201742 1.14337377679658e-32 -134.456803462007 571.610360288666 -0.235224573945975 0.814210779816214 SENP3 other 9.82509966859484e-30 1 1.80870297751451e-28 13.6432372201742 -0.235224573945975 0.00017912711340915 331.43957728677 78.6481523448178 4.21420678560428 3.41361806450375e-05 329.06901468339 228.94275298872 1.43734191359009 0.151770225920405 FGF11 other 1 1 0.334978340669753 4.21420678560428 1.43734191359009 1.9705259541515e-30 4700.94327050765 371.96785633437 12.6380362992491 3.9010485613974e-29 -448.210198106673 1082.80609690595 -0.413933943840367 0.679247493359247 EIF4A1 essential 3.08998174870497e-26 1 6.14493169391318e-25 12.6380362992491 -0.413933943840367 4.49883442494954e-19 2165.99091371344 231.972561328818 9.33727205194399 3.6074678812529e-18 -307.627340658362 696.856754059511 -0.441449894639453 0.659236765914065 RPL26 essential 6.49046842487471e-15 1 5.45773815754752e-14 9.33727205194399 -0.441449894639453 2.82380614930777e-12 150.580787876843 25.7362063782312 5.85093178317886 1.46535694579305e-08 -41.7989109705578 47.0709049623434 -0.887998881772017 0.375362092998295 POLR3K essential 3.41878210496692e-08 1 0.000180546629291161 5.85093178317886 -0.887998881772017 6.12745871331859e-11 279.799068931199 52.7098373449121 5.30828936352633 2.37359693370617e-07 -103.179412463477 96.4050298548104 -1.07027001204055 0.285490336541226 SNRNP25 essential 7.03861182398907e-07 1 0.00274435277475108 5.30828936352633 -1.07027001204055 9.97028279455983e-09 314.01611395593 62.1614894338451 5.05161824171088 8.06106251839387e-07 -30.2170591339166 113.787173356918 -0.26555769198286 0.790781774144659 WDR90 other 0.000101653094906587 1 0.00899533966427572 5.05161824171088 -0.26555769198286 9.71200786307027e-21 418.171125526794 86.1553101641508 4.85368951408865 2.04882847448241e-06 -784.521167808648 157.708081041083 -4.97451470228899 1.16326347897279e-06 JMJD8 other 1.43310388027465e-16 0.0181934408111344 0.0222215936342362 4.85368951408865 -4.97451470228899 0.0139720604084456 -19.8434135165214 20.1005241278157 -0.987208760843277 0.32442088932766 -104.945485212104 36.7941927442198 -2.85222958801266 0.00467577588972873 CCDC78 other 1 1 1 -0.987208760843277 -2.85222958801266 5.14910825619032e-07 138.572688777857 47.6603764342051 2.90750302757588 0.00394583726951847 -193.913967248493 87.3352412069022 -2.22034043266795 0.0272260383967327 SPSB3 other 0.00469650164047119 1 1 2.90750302757588 -2.22034043266795 0.538401246973128 -6.06898024521629 10.9917341364765 -0.552140378384531 0.581308918013556 -22.357802116153 20.1417996229329 -1.1100200843373 0.267977984582299 MEIOB other 1 1 1 -0.552140378384531 -1.1100200843373 0.10781989697973 -16.6264089643675 10.4875795404316 -1.58534282388701 0.114058943522656 -39.5490450336188 19.2179616983222 -2.05792089996056 0.0405576252809189 HS3ST6 other 1 1 1 -1.58534282388701 -2.05792089996056 1.21974640073014e-08 244.890076012379 43.9393891229187 5.57336096155796 6.02996889357934e-08 51.9179173742157 81.3236932656582 0.638410717582841 0.523745485267084 CCNF other 0.000123596902785985 1 0.000721304879049961 5.57336096155796 0.638410717582841 4.84764415211977e-08 66.3651817343476 25.2603475803842 2.62724736954464 0.00909817689561504 -145.397660836166 46.7522375576126 -3.10996154263189 0.00207068065805849 TBC1D24 other 0.000473372451454496 1 1 2.62724736954464 -3.10996154263189 6.27232950742705e-07 81.3404202616113 24.8421495497345 3.27429074117624 0.00119696191992118 -89.1146005246557 45.9782302478225 -1.93819118405228 0.0536383913176778 AMDHD2 other 0.00567771267012296 1 1 3.27429074117624 -1.93819118405228 0.000464442549582342 -6.40111415457504 41.5089123381541 -0.154210597050293 0.877558466165449 -256.672650774849 74.8561876361764 -3.42887687551436 0.000700409007999338 BICDL2 other 1 1 1 -0.154210597050293 -3.42887687551436 8.8537607550915e-10 249.655987251432 65.3215480914411 3.82195453944153 0.000164270532818326 -304.35701678262 118.27506326679 -2.57329827925004 0.0106056795285428 PAQR4 other 9.59271415967702e-06 1 1 3.82195453944153 -2.57329827925004 1.41104582541927e-11 75.5644198232943 19.9377319789164 3.7900208460622 0.000185669790474971 -119.187815317634 36.100438218359 -3.30156145464796 0.0010905435462485 FLYWCH2 other 1.66588070148999e-07 1 1 3.7900208460622 -3.30156145464796 0.117655631468133 -37.9546805774787 30.9414385962995 -1.22666179400004 0.221014412811656 -116.153389618604 56.0244010509346 -2.07326428198675 0.0390925592119466 ZG16B other 1 1 1 -1.22666179400004 -2.07326428198675 0.00163552880947916 24.2518557975727 22.3585772387998 1.08467795327725 0.279021257555863 -94.8181801950056 40.0780459846444 -2.36583840018883 0.0186881453670573 ZNF75A other 1 1 1 1.08467795327725 -2.36583840018883 0.00107763557977159 72.9182420926774 54.3404616653702 1.34187748609332 0.180754822652533 -226.040592732148 99.7801311804511 -2.26538680655126 0.0242754958471497 ADCY9 other 1 1 1 1.34187748609332 -2.26538680655126 0.0180915668681078 48.4437398113826 30.5532015324007 1.58555363698988 0.114196818937099 -165.716767235895 96.7316650644484 -1.71315946154224 0.0880133614557632 SHANK2 other 1 1 1 1.58555363698988 -1.71315946154224 1.26897222066354e-20 182.676651727442 19.5568946002015 9.34078009120935 4.07787620649332e-18 -53.7965373054634 50.2871940205493 -1.06978602312708 0.285689068053543 CLPB other 1.86932297825946e-16 1 6.16778776232114e-14 9.34078009120935 -1.06978602312708 2.19128867231432e-12 89.4507973293676 13.9605237413834 6.40740984983303 6.49278048307854e-10 -55.6673983355564 36.1840231078892 -1.53845243160425 0.125100501143348 NEU3 other 2.66657918533929e-08 1 8.44515957434025e-06 6.40740984983303 -1.53845243160425 3.25607172825771e-06 -56.22739327203 58.6755488837781 -0.95827639181361 0.338780692572563 -622.666477925522 123.025129314082 -5.06129504920788 7.71259226401982e-07 CYB561A3 other 0.0277677796985817 0.0120933446699831 1 -0.95827639181361 -5.06129504920788 0.25912328830018 -2.14736763720314 9.45539479422287 -0.227105021412237 0.820513939424678 -30.8946289539224 19.1984038480712 -1.60922903791433 0.108734827555893 PPP1R32 other 1 1 1 -0.227105021412237 -1.60922903791433 0.338149547443732 28.0280633770472 38.3059459503624 0.731689628899036 0.4649949649581 -75.2129479897204 78.232961321317 -0.961397174789372 0.337215882201708 ASRGL1 other 1 1 1 0.731689628899036 -0.961397174789372 0.156549272423226 0.904378397018974 3.1973154629095 0.282855541628665 0.777504306330715 -11.1196269497096 6.51381308730933 -1.70708413039571 0.0889560506700778 GNG3 other 1 1 1 0.282855541628665 -1.70708413039571 1.93739939217137e-09 310.154610545115 74.6292950936314 4.15593648788976 4.35269231518104e-05 -519.729034704871 151.786922901393 -3.42406990516903 0.000712757559569218 UBXN1 other 2.06178043314877e-05 1 0.423168746881901 4.15593648788976 -3.42406990516903 5.10641395439973e-06 213.0371928679 54.1821717516709 3.93186884136534 0.000107289695854963 -192.784002274857 110.844220417403 -1.73923368804341 0.0831375947836277 LBHD1 other 0.0428632387332314 1 1 3.93186884136534 -1.73923368804341 1.3836484294665e-08 65.6461070336538 16.3926889760998 4.00459663020291 8.03554844004786e-05 -102.37363655736 33.2106469575263 -3.0825547207282 0.00226476470892512 TTC9C other 0.000139679308954643 1 0.761448570178935 4.00459663020291 -3.0825547207282 8.91080781392384e-08 71.3674407068853 20.4359923187012 3.49224249030355 0.000559116181674745 -134.871459205101 41.8512896759126 -3.22263567621253 0.00142543161123629 TAF6L other 0.000855704874371106 1 1 3.49224249030355 -3.22263567621253 0.0103343107562763 42.193652807482 70.2378421171678 0.60072535738066 0.548525000319719 -379.994055170913 143.513012453665 -2.64780209595 0.00857642838839923 NXF1 essential 1 1 1 0.60072535738066 -2.64780209595 2.11614611161582e-08 92.1865588864318 35.2944750102119 2.6119260552752 0.00950543311324128 -321.163881538405 72.1152056926313 -4.45348354003546 1.23639797405385e-05 STX5 other 0.000211360673628188 0.18987363687545 1 2.6119260552752 -4.45348354003546 0.00933664845517819 3.3186345635644 10.4747340886925 0.31682279812209 0.751621988300323 -69.4902741564207 24.5474928610327 -2.83085016257327 0.00499019267116733 SLC25A45 other 1 1 1 0.31682279812209 -2.83085016257327 5.40108136403734e-08 2778.69196738439 523.268500668069 5.31026034213174 2.28321275524817e-07 -994.601653429984 1236.82705227688 -0.804155804644652 0.422011847430018 RPL29 essential 0.000526119335670878 1 0.00264190547909766 5.31026034213174 -0.804155804644652 0.454296894857995 -6.63538892782061 5.89538701985222 -1.12552219311073 0.261359954429924 -12.6978416257884 14.1583734310665 -0.896843248810394 0.370595645988873 ITIH3 other 1 1 1 -1.12552219311073 -0.896843248810394 5.11575089984194e-09 147.043395106324 31.6102323618818 4.65176571380225 5.15107109411454e-06 -204.607425079947 73.1155936125213 -2.79841022920872 0.00550409638074973 ZFPL1 other 5.30554525822607e-05 1 0.054137277456828 4.65176571380225 -2.79841022920872 8.24598088600397e-05 187.068453418515 67.265410890408 2.78104973926787 0.00579559582112626 -369.813649740967 154.78720303623 -2.38917457313578 0.01756543437282 RPS6KA4 other 0.617437026024689 1 1 2.78104973926787 -2.38917457313578 2.45060494471573e-36 1090.47544946545 75.7816958614392 14.3896944647333 5.04823159038957e-35 -333.713434413632 322.778084444407 -1.03387884895608 0.302142539626005 LRP5 other 3.87783726451817e-32 1 8.00346636340362e-31 14.3896944647333 -1.03387884895608 4.24004653005772e-11 80.2644733424457 12.7684667695864 6.28614811714354 1.54946636824984e-09 -68.4291543464628 41.7864210338077 -1.63759309013566 0.102833614130028 TPCN2 other 4.90361381201176e-07 1 1.98812029710137e-05 6.28614811714354 -1.63759309013566 0.439659092353813 55.5303928929242 43.2705237897115 1.28333073024015 0.200645712864731 47.7115161041656 145.705799332339 0.327451043972112 0.743619523185045 FGF19 other 1 1 1 1.28333073024015 0.327451043972112 0.000101794061634335 -584.470537679957 169.049470366254 -3.45739348614149 0.000633128898677604 -1207.56495982331 295.114780803181 -4.09184845481754 5.64979174713041e-05 PDZK1IP1 other 0.75398861452552 0.851028130870254 1 -3.45739348614149 -4.09184845481754 0.399583282170016 3.42867640930913 17.2632125266264 0.198611724441254 0.842715398832117 -31.0456788365776 30.1369129978125 -1.0301545761781 0.30385596735313 TAL1 og 1 1 1 0.198611724441254 -1.0301545761781 3.1028076636031e-10 152.389961718873 139.493099856867 1.09245519581427 0.275610490425332 -1251.36256323021 241.11530734984 -5.18989265751834 4.15072983993388e-07 CMPK1 essential 3.44597819119761e-06 0.00652702267329603 1 1.09245519581427 -5.18989265751834 1.9255860899985e-06 44.3025368293068 11.1631950644482 3.96862516273666 9.28813135165648e-05 -14.7921174571392 19.154904901209 -0.772236538548702 0.440654793813138 BEND5 other 0.0167660780856169 1 0.874106041504392 3.96862516273666 -0.772236538548702 0.538093436884963 -0.682208063674193 22.9978745551129 -0.0296639614256234 0.976357214629738 -34.412383608799 36.6297846925321 -0.939464534057577 0.348341402389279 ELAVL4 other 1 1 1 -0.0296639614256234 -0.939464534057577 7.51697410750958e-17 150.892728727314 29.2229233115215 5.1635056191597 4.69826837524956e-07 -196.417215920859 51.786154222701 -3.79285194795865 0.000183671049117657 COA7 other 1.04095057440793e-12 1 0.00532266824232023 5.1635056191597 -3.79285194795865 2.97602199158922e-13 183.838740480238 29.3383642103249 6.26615509857025 1.45601932670447e-09 -49.3197608456249 51.5490197407098 -0.956754582215181 0.339547014069113 ZYG11B other 3.73520520164363e-09 1 1.87040242708456e-05 6.26615509857025 -0.956754582215181 0.662898467490906 0.510566827407271 3.75400580406329 0.136005870543578 0.891917613678099 -4.55837427577925 6.58931742714983 -0.691782468544841 0.489666190634966 SLC1A7 other 1 1 1 0.136005870543578 -0.691782468544841 8.49886897829621e-21 135.410741569553 21.6582466203859 6.25215623143275 1.56038630451554e-09 -148.513639729787 38.3424028229027 -3.87335244522226 0.000134546055427204 C1orf123 other 1.255027982025e-16 1 2.00181959006299e-05 6.25215623143275 -3.87335244522226 6.49868867931526e-23 257.826068437433 32.1722096442305 8.01393722372654 3.290483749246e-14 -134.246170985484 56.9556642097181 -2.35702932883326 0.0191307001961387 MAGOH essential 9.80457161048294e-19 1 4.75606521116017e-10 8.01393722372654 -2.35702932883326 0.000160555798265017 51.5450997187477 27.0225326423862 1.90748588967921 0.0575108495063244 -105.701664594837 47.868573587335 -2.20816407662508 0.0280671679596758 ACOT11 other 1 1 1 1.90748588967921 -2.20816407662508 0.00945309430937409 33.7297549086703 20.0809834448129 1.67968640586589 0.0941665271982577 -46.2038222542975 35.572092610828 -1.29887838648641 0.195085674015132 FAM151A other 1 1 1 1.67968640586589 -1.29887838648641 1.31102099062742e-25 83.448569405099 8.33706462884237 10.0093465890148 2.83635431225753e-20 -3.51249251315268 14.7510989499914 -0.238117344684664 0.811970024022574 PARS2 essential 2.0155636709906e-21 1 4.34614571267221e-16 10.0093465890148 -0.238117344684664 2.88403278391708e-13 351.230122851565 56.5840047873575 6.20723337224868 2.02331447772643e-09 -99.3620117453461 100.502591687395 -0.98865123851138 0.32371895359877 USP24 other 3.62234517659985e-09 1 2.58417725095219e-05 6.20723337224868 -0.98865123851138 0.507176325866871 -87.8955799416588 148.819032078773 -0.590620559171046 0.555265096376375 -280.031165439645 240.50210150577 -1.16436057600489 0.245298156966452 PLPP3 other 1 1 1 -0.590620559171046 -1.16436057600489 1.48422049598903e-13 179.205692154299 35.0180119981005 5.11752900661579 5.89788731941809e-07 -140.351900990471 55.5284926141304 -2.52756547824523 0.0120588032546202 NOL9 essential 1.88169474481489e-09 1 0.00664043133293283 5.11752900661579 -2.52756547824523 0.00125684336102719 79.7737074593689 22.2558366464215 3.58439490398559 0.00040031660511268 44.7908603467651 35.9670091215232 1.24533180380466 0.214081551546798 PRKAA2 other 1 1 1 3.58439490398559 1.24533180380466 0.000639612542315867 369.201184238993 130.527031481144 2.82854195065586 0.00502790546248007 -146.184192902091 206.978320298085 -0.706277800938571 0.480626657627703 KLHL21 other 1 1 1 2.82854195065586 -0.706277800938571 8.30637622710988e-07 71.5947994921494 14.9919982293366 4.77553414807985 2.93790307548225e-06 7.77644743059482 25.9775895512191 0.29935215564409 0.764900814769689 ZSWIM5 other 0.00743919054899961 1 0.0314885158131259 4.77553414807985 0.29935215564409 3.28633905609839e-11 83.2709643107069 21.255551508648 3.91761014889816 0.000113277503629104 -90.4202379286209 30.8929329468743 -2.92689069322469 0.00371408232375167 GMEB1 other 3.81741144756389e-07 1 1 3.91761014889816 -2.92689069322469 0.0869686500131771 7.71505395795561 5.83576887575708 1.3220287030224 0.187269288538595 -7.68881579320179 9.33914425365734 -0.823289113474261 0.411064838558213 SLC45A1 other 1 1 1 1.3220287030224 -0.823289113474261 0.00276324776534003 634.85221264488 250.55047444483 2.53382961677317 0.0118461773190127 -173.177726992343 359.735893288714 -0.481402412778852 0.630619005965834 SELENON other 1 1 1 2.53382961677317 -0.481402412778852 2.58222685124448e-66 904.301299838445 39.3650912753083 22.9721631664466 1.18986710069894e-65 158.972472406182 155.52349978375 1.02217653683994 0.30760560698499 AK4 other 4.11916827310519e-62 1 1.89783802561481e-61 22.9721631664466 1.02217653683994 1.04900063403758e-29 795.356314822351 63.4292967509336 12.5392579701058 9.01033643915539e-29 -125.225540838852 250.596299918017 -0.499710254619961 0.617683097605091 JAK1 og 1.64189579239563e-25 1 1.41822695552306e-24 12.5392579701058 -0.499710254619961 1.91180411489388e-44 185.726158584278 11.4279034856647 16.2519887236758 6.2831610450573e-42 -66.1086674341614 45.2938146860495 -1.45955177086294 0.145571485019686 RAVER2 other 3.04015090350424e-40 1 9.98708448111857e-38 16.2519887236758 -1.45955177086294 5.639144300414e-20 190.574408195969 29.976669226833 6.35742439408111 8.58339941900115e-10 -162.676107194166 47.631867637747 -3.41527878838094 0.000734045599217708 LZIC other 8.24048156619498e-16 1 1.11155022476065e-05 6.35742439408111 -3.41527878838094 0.113266493128385 23.9335271057485 20.4720057942042 1.16908559651367 0.243388916551865 68.3440536235502 32.6274139962256 2.09468190250862 0.037121003789099 RBP7 other 1 1 1 1.16908559651367 2.09468190250862 7.02330905440269e-06 435.9452502949 155.869884177439 2.79685362310676 0.0055271705432735 -470.70210852256 242.104784634536 -1.94420820403487 0.0528974800879714 FBLIM1 other 0.0582232320609983 1 1 2.79685362310676 -1.94420820403487 0.0761277317764748 1.19125764892363 3.33425138570647 0.35727889445601 0.721159060166075 -8.79531480389268 5.17892354840611 -1.69829014112394 0.0905923986135966 SLC25A34 other 1 1 1 0.35727889445601 -1.69829014112394 0.0574162040579442 61.5134083771735 28.5283294863825 2.15622188486486 0.0319430596883886 17.9234923955737 41.895369077086 0.427815598487631 0.669123900284228 AKR7A3 other 1 1 1 2.15622188486486 0.427815598487631 0.00316505084326759 25.3178615207459 13.5545208185612 1.86785367477368 0.0628577148363781 -29.6733460866982 21.2108749376753 -1.39896850902608 0.16296167845769 DRAXIN other 1 1 1 1.86785367477368 -1.39896850902608 0.00542729941746147 1074.82077501436 330.161235168505 3.25544207049564 0.00127497763341344 865.707317272376 553.996865095617 1.56265742970036 0.119291624714398 PDPN other 1 1 1 3.25544207049564 1.56265742970036 0.195227014909846 26.5182101267819 34.4388409419085 0.770008786634628 0.441962906177311 108.248813615262 60.0684674987114 1.80209048312385 0.0726382502540798 LRRC38 other 1 1 1 0.770008786634628 1.80209048312385 1.24020909745655e-06 105.884729254586 282.421197824856 0.374917782624271 0.708013772473799 -1904.47989758881 448.608072170313 -4.24530902525931 2.9984341536875e-05 DHRS3 other 0.0109622082124184 0.455642053994353 1 0.374917782624271 -4.24530902525931 0.000507314228260585 4.32483559076885 1.5359105782442 2.81581210002007 0.00522408420002985 -1.50739218103185 2.23438901684603 -0.674632827885817 0.500486312813524 MATN1 other 1 1 1 2.81581210002007 -0.674632827885817 0.223976199210065 -928.666896665145 612.183924808688 -1.51697367250432 0.130443261628458 -1378.42651369981 887.386144263958 -1.55335591231611 0.121509474520788 LAPTM5 other 1 1 1 -1.51697367250432 -1.55335591231611 0.000344847021846296 673.254350796821 218.839340796688 3.07647769521617 0.00230982352101984 -131.141959795923 313.745545764091 -0.417988276061553 0.676287920535426 SDC3 other 1 1 1 3.07647769521617 -0.417988276061553 9.31836880787263e-19 257.550443906376 75.606997511451 3.4064366048575 0.000759550727891091 -626.956793112725 107.591985320441 -5.82717003729841 1.61922170162764e-08 PEF1 other 1.33672000548933e-14 0.000257051445133388 1 3.4064366048575 -5.82717003729841 4.3066394384354e-13 128.570160701241 32.9669142918668 3.89997558045524 0.0001214786672868 -173.984295105918 47.013045017746 -3.7007663519826 0.000260495384226707 SYNC other 5.37597801099891e-09 1 1 3.89997558045524 -3.7007663519826 4.37489397893331e-16 1169.41256703092 265.233391968361 4.40899450236045 1.50255338538545e-05 -1542.1876651794 377.957533798522 -4.08031994938746 5.93193074991417e-05 RBBP4 essential 5.94548091737037e-12 0.892814897169581 0.152043377067153 4.40899450236045 -4.08031994938746 9.50150896212544e-07 153.145127830536 354.762693471947 0.43168329322273 0.666316114880172 -2167.50796201607 505.915547058894 -4.28432764048611 2.55147027424217e-05 KIAA1522 other 0.0084686949379424 0.388512378658855 1 0.43168329322273 -4.28432764048611 5.30574974923371e-05 8.25557598870003 5.00849480679878 1.64831477462919 0.100459872337922 -18.4828021034044 7.15813105928993 -2.58207092749681 0.0103522074134696 TSSK3 other 0.405253165846471 1 1 1.64831477462919 -2.58207092749681 2.2550782430301e-07 80.9096995561668 32.2988139553065 2.50503624275881 0.0128268122838525 -124.371554899854 47.3645162311645 -2.62583817583722 0.00913132817271079 TMCO4 other 0.00211052772765187 1 1 2.50503624275881 -2.62583817583722 0.0171581073104844 95.3234641255984 37.7651359180978 2.52411283074232 0.0121665387787795 21.8364877746452 55.3805906198299 0.394298571579811 0.693668450652436 UBXN10 other 1 1 1 2.52411283074232 0.394298571579811 0.00980893647319037 222.046250543144 115.693439585698 1.91926397329269 0.0559932966510174 -133.378093390325 169.658359736635 -0.786156919101255 0.432457397290299 CAMK2N1 other 1 1 1 1.91926397329269 -0.786156919101255 0.550417865573766 183.005310374895 291.012760099546 0.628856653269412 0.529968721613279 -146.51939196994 428.067951815919 -0.342280685457497 0.732403032337794 ALPL other 1 1 1 0.628856653269412 -0.342280685457497 0.00087599157318153 67.0653917717588 64.2081236944767 1.04450010236832 0.297184866307015 -218.911150161947 95.182405319257 -2.29991193674591 0.0222133914744698 WNT4 other 1 1 1 1.04450010236832 -2.29991193674591 0.252179213083806 0.460741823638979 4.93586129546976 0.0933457802110155 0.925700477766056 -10.2822763575519 7.75981012319321 -1.32506803572672 0.186307435347155 TTLL10 other 1 1 1 0.0933457802110155 -1.32506803572672 0.413104285733353 -5.87662866449524 8.5524691673465 -0.687126553689586 0.492608430627787 -17.879653327129 13.4345447740886 -1.33087154256344 0.184383911816312 SCNN1D other 1 1 1 -0.687126553689586 -1.33087154256344 0.187477732082713 -113.536237785018 124.9179530002 -0.908886473546649 0.364242176873462 -359.460679385762 196.225885160294 -1.83187187099258 0.0681013939418504 MXRA8 other 1 1 1 -0.908886473546649 -1.83187187099258 5.92373819190609e-14 197.005219911974 60.9684696362274 3.23126398099574 0.00138641346726834 -463.316370970316 97.3206596563484 -4.76071959033513 3.1603803029559e-06 FAAP20 other 7.60489509076904e-10 0.0490996683867228 1 3.23126398099574 -4.76071959033513 0.0168477834552783 133.068697017208 85.4214603807966 1.55779000293377 0.120458730848743 -158.708048004427 134.262629698136 -1.18207164838981 0.238221127252965 MEGF6 other 1 1 1 1.55779000293377 -1.18207164838981 0.000850827390620341 5.3545925630659 1.66031525394215 3.22504569560044 0.00141571750569312 0.278503109358707 2.61037128678371 0.106690994790192 0.915113946952913 CCDC27 other 1 1 1 3.22504569560044 0.106690994790192 0.618418907717943 -136.625953267272 246.377090128232 -0.554540006930686 0.579666687729139 -373.178532001518 380.303410931057 -0.981265277342383 0.327337142936967 DIRAS3 other 1 1 1 -0.554540006930686 -0.981265277342383 0.628065824503009 -10.0802126109242 10.6270106640587 -0.948546390850646 0.343699581139385 -11.6852640786078 17.405579363096 -0.671351630120592 0.502570509356676 C1orf87 other 1 1 1 -0.948546390850646 -0.671351630120592 5.64876423632243e-05 114.697068590404 59.5443963029176 1.92624454544657 0.0551196906657794 -235.618000687049 99.8927014363891 -2.35871086975347 0.0190486459248435 NFIA other 0.430435834807769 1 1 1.92624454544657 -2.35871086975347 6.76888053328406e-14 78.8982733739874 15.8349924474509 4.98252674485413 1.11998815641583e-06 -70.9825382619332 25.9783986452573 -2.7323677348716 0.00670142740548563 OMA1 other 8.67296662729686e-10 1 0.0123713891757693 4.98252674485413 -2.7323677348716 7.69562869079891e-12 157.448601375432 36.8285004933332 4.27518360145924 2.64844381447431e-05 -169.080965798595 60.255668796781 -2.80605906755162 0.00537877545399372 MYSM1 other 9.16395464500334e-08 1 0.262672657519562 4.27518360145924 -2.80605906755162 2.39722593592134e-47 309.192766844427 18.9032777848808 16.3565689698389 2.40670707676742e-42 -106.887101426413 58.7387650425457 -1.8197029057215 0.0699034369550485 TM2D1 other 3.81518507701882e-43 1 3.82642358135251e-38 16.3565689698389 -1.8197029057215 1.42372449384239e-28 494.541667103166 43.0320865409842 11.4923933942213 3.39790214744934e-25 -193.646291388103 133.955232204706 -1.44560453668715 0.149435110776308 USP1 other 2.21702378181138e-24 1 5.31262000753705e-21 11.4923933942213 -1.44560453668715 7.79675720818422e-08 391.81756258003 88.3195327426586 4.43636362662481 1.33339804346079e-05 -161.093622737202 150.545699957146 -1.0700645902411 0.285545889751694 FUBP1 other 0.000751529427296877 1 0.135553245098224 4.43636362662481 -1.0700645902411 0.695765092982583 -12.1576263526577 26.0784467989165 -0.466194418954537 0.641452231229986 16.643192146426 44.4522055905512 0.374406442274794 0.708395828864482 NEXN other 1 1 1 -0.466194418954537 0.374406442274794 0.0554993122253586 133.677640307097 55.5393423702878 2.40689994879399 0.0167577568290382 134.824567499359 94.5674501110634 1.42569739737105 0.155106524713132 DNAJB4 other 1 1 1 2.40689994879399 1.42569739737105 0.798030354141444 -20.5227965296351 30.5825037374672 -0.671063321231356 0.502751746255724 -16.5595738767331 52.4367332114284 -0.31580102082187 0.752396616364364 ADGRL4 other 1 1 1 -0.671063321231356 -0.31580102082187 0.0160115016019784 7.66880997951839 4.75322771682506 1.61338998179553 0.107819336497088 -9.56620543354813 8.24763251411745 -1.15987289894084 0.247117657092439 LRRIQ3 other 1 1 1 1.61338998179553 -1.15987289894084 2.69592409623627e-20 208.31091964585 23.0338363597262 9.04369191447734 2.94720326296866e-17 20.6553841497035 39.9525660356244 0.516997684986884 0.605577903579251 TYW3 other 3.95545983399786e-16 1 4.42168905543189e-13 9.04369191447734 0.516997684986884 0.00164410742839484 71.759730383486 21.0719838525117 3.40545678497815 0.000760601121808596 26.8465070428779 36.2259605048702 0.741084754378526 0.459283722361929 LHX8 other 1 1 1 3.40545678497815 0.741084754378526 1.17925096165265e-08 49.259758364312 31.0128367874136 1.58836673671542 0.113365130105115 -206.165548608764 49.7389384050812 -4.14495273159475 4.54408758041252e-05 SNX7 other 0.000119576047511578 0.68692971953096 1 1.58836673671542 -4.14495273159475 0.495551266962304 -6.81078487883683 9.56584112886674 -0.711990172854115 0.477104364113064 -26.2794184168014 26.3386906123061 -0.997749614953257 0.319321381054856 B3GALT2 other 1 1 1 -0.711990172854115 -0.997749614953257 0.27496580531331 22.7168923813052 14.3082459581235 1.58767835329304 0.113542572413539 16.1546036186651 21.1587962411259 0.763493510432592 0.445843229839107 NTNG1 other 1 1 1 1.58767835329304 0.763493510432592 9.38548876873542e-07 126.183782604607 44.5726141955488 2.83097109922731 0.00498967155821681 -120.733628696154 66.5882733642268 -1.8131364968087 0.0709211165270262 FAM102B other 0.00836904033508137 1 1 2.83097109922731 -1.8131364968087 6.87873957034506e-14 135.958104840945 33.8446052629214 4.01712780470494 7.64303059617289e-05 -156.159750227187 50.5614011613619 -3.08851706322019 0.00222134450539163 HENMT1 other 8.81304113752609e-10 1 0.725935046024501 4.01712780470494 -3.08851706322019 3.37603216825701e-27 110.650511090342 15.7656027620144 7.01847641099669 1.77491293373035e-11 -137.320266970695 27.0626365872412 -5.07416439370269 7.2044769633335e-07 C1orf52 other 5.22981143184694e-23 0.0113009425646849 2.4255960152359e-07 7.01847641099669 -5.07416439370269 0.981261583907036 -0.242323858548592 6.53185777949609 -0.0370987652715375 0.970433369383442 -2.04469899739194 11.2123396735553 -0.182361492509403 0.855434385527961 WDR63 other 1 1 1 -0.0370987652715375 -0.182361492509403 0.345655557505604 -121.095532380398 114.87651653522 -1.05413652879414 0.292755885912101 -291.998557689354 207.908401570151 -1.4044577106271 0.161323465211749 GBP2 other 1 1 1 -1.05413652879414 -1.4044577106271 4.34951610730212e-11 61.7484475318388 14.580712931761 4.23494021319992 3.12771141723546e-05 -41.3769287443427 21.7092416650668 -1.90595919390975 0.0577056772261125 ATXN7L2 other 5.02891052326272e-07 1 0.308079574597693 4.23494021319992 -1.90595919390975 0.335548070511848 -216.973098237836 152.59064655069 -1.42192921481435 0.156192438017193 -289.947598568438 269.850654803841 -1.07447431906069 0.28356237575712 GBP4 other 1 1 1 -1.42192921481435 -1.07447431906069 0.000276625844639179 116.377322965646 33.1000719279608 3.51592356714299 0.000513533646767661 -3.49804943549445 58.5999902246816 -0.0596936863313863 0.952443595864525 ZNF326 other 1 1 1 3.51592356714299 -0.0596936863313863 0.44049429184608 23.5041859183587 18.3389587596885 1.28165324031504 0.201093071676312 2.19563150596174 52.2029554136231 0.0420595249553392 0.966483158772692 BRINP3 other 1 1 1 1.28165324031504 0.0420595249553392 0.00157597232260019 23.7968222597265 10.1434856201325 2.34602020951213 0.0196906839599526 -21.3316944987269 17.9464323292257 -1.18863148437521 0.235617641725118 GFI1 other 1 1 1 2.34602020951213 -1.18863148437521 0.554688583416261 4.46564300784006 6.94348372647446 0.643141567512175 0.520688359801123 -15.0728401172928 18.8851166009711 -0.798133283250033 0.425507795605962 KCNT2 other 1 1 1 0.643141567512175 -0.798133283250033 1.08500054960344e-07 84.1687503620501 43.7843126137318 1.92234947490423 0.0556061461737999 -246.734297772388 70.1178281034723 -3.51885254358255 0.000507855673736913 AGL other 0.00103726052542089 1 1 1.92234947490423 -3.51885254358255 0.41287754503267 -101.179970627808 411.742230861216 -0.245736198631304 0.806072452156244 -708.128442407009 592.850513716298 -1.19444687323975 0.233347589493863 VCAM1 other 1 1 1 -0.245736198631304 -1.19444687323975 1.45536774106226e-09 116.338087993458 33.5358061198575 3.46907086645432 0.000607363588427265 -117.319006119415 48.2868124662907 -2.42962830071495 0.0157643079991843 EXTL2 other 1.55957207132232e-05 1 1 3.46907086645432 -2.42962830071495 4.15430073223895e-15 112.309929383625 35.5685524537687 3.15756255556374 0.00177075789124167 -233.082559978692 51.2136793698714 -4.55117778778091 8.06149547840762e-06 SLC30A7 other 5.51234164160787e-11 0.124300198781567 1 3.15756255556374 -4.55117778778091 3.04421458799646e-06 113.520750422804 22.2914103634543 5.0925781981438 6.59373282880759e-07 -14.723512415585 61.5124255395446 -0.239358345674724 0.811007328916888 ZNF281 other 0.0260249905127817 1 0.0074021244736194 5.0925781981438 -0.239358345674724 7.34763058282911e-08 963.798220376006 179.578588321707 5.36699964836233 1.71581356260744e-07 -1185.1781464148 553.345486553444 -2.14184117376067 0.0330944913235353 ARPC5 other 0.000709560685383807 1 0.00200063861400027 5.36699964836233 -2.14184117376067 0.724749688213012 -0.126719134420238 22.8010431327777 -0.00555760250451316 0.995569786467079 -64.9721695494672 81.1337519357433 -0.80080321690194 0.423947079068847 CADM3 other 1 1 1 -0.00555760250451316 -0.80080321690194 0.28507123914633 -8.68361033684905 6.43921090580106 -1.34855193654645 0.178606828945384 11.3100498066307 17.1098265212714 0.661026562283943 0.509156840636167 NLRP3 other 1 1 1 -1.34855193654645 0.661026562283943 1.64569008527186e-06 208.465775495391 41.2685972746354 5.05143836385053 8.06800330293116e-07 -104.592083929747 110.641366433864 -0.945325309157912 0.345334899634111 ZNF496 other 0.0144096623866404 1 0.00900227808541059 5.05143836385053 -0.945325309157912 0.926722502174845 0.807737097875821 4.13861664362373 0.195170794357164 0.845404950358973 -3.41471306501304 11.0588609391592 -0.308776200713549 0.757728140611256 TRIM58 other 1 1 1 0.195170794357164 -0.308776200713549 0.126449902649374 -12.4954616933278 9.78145829102689 -1.27746408782325 0.202527736843769 -61.0382239380735 36.5159556285989 -1.67154940593337 0.0957632123182072 SLAMF9 other 1 1 1 -1.27746408782325 -1.67154940593337 4.77221437855727e-09 395.96021551844 61.7444592235058 6.4128866055029 6.26220730246771e-10 68.3473431658433 230.834167040425 0.296088503890647 0.7673875980453 IGSF8 other 4.95355852494245e-05 1 8.14838414197099e-06 6.4128866055029 0.296088503890647 0.0646501816454462 -134.894243284177 57.348095708095 -2.35220091650115 0.0193730696660073 -27.1736298100256 194.100519178282 -0.139997718321745 0.888765023992749 DDR2 other 1 1 1 -2.35220091650115 -0.139997718321745 1.75268996114548e-08 846.07739777067 136.971357924717 6.17703883928564 2.37202417815147e-09 269.483101499674 512.176515338133 0.526152788012478 0.599210790187172 PEA15 other 0.000175882437600949 1 3.02148439812934e-05 6.17703883928564 0.526152788012478 2.91061190910182e-15 456.952347525998 53.1101534907456 8.60386042012892 6.16626943317786e-16 -156.211897347727 198.554464588431 -0.786745831535578 0.432113089570105 PEX19 other 3.87460657339634e-11 1 9.12484550721659e-12 8.60386042012892 -0.786745831535578 1.70127238299629e-13 963.863452160439 120.474020283543 8.00059174494159 3.55402153433401e-14 -333.308974961577 450.397014920749 -0.740033712302079 0.459915463490767 NCSTN other 2.1529602006818e-09 1 5.1330733020386e-10 8.00059174494159 -0.740033712302079 6.52132129916442e-09 711.084664595679 113.629195780539 6.25793978133095 1.51064991423843e-09 -299.858350313671 429.270847666159 -0.698529499368354 0.485442909436294 VANGL2 other 6.72022159878893e-05 1 1.9393723598993e-05 6.25793978133095 -0.698529499368354 0.186438221277096 -15.6613961140039 10.032544122921 -1.56105928088796 0.119672473292373 32.6996349629774 37.8415563123071 0.864119717833661 0.388283508433202 SLAMF6 other 1 1 1 -1.56105928088796 0.864119717833661 0.443930527018191 -48.9005638411571 51.3375703474952 -0.952529765436065 0.34167096066362 -163.543000145139 179.911973790178 -0.909016763586121 0.364143068782648 OLFML2B other 1 1 1 -0.952529765436065 -0.909016763586121 0.107140803643905 5.27301435112088 2.87948784387665 1.8312334126828 0.0681554537061539 -9.61361927087688 10.0911347769295 -0.952679701876115 0.341595102171297 FCRLB other 1 1 1 1.8312334126828 -0.952679701876115 0.504833891262483 -37.8337570205262 34.7192611327495 -1.08970513156569 0.276803991804777 -60.4704291262222 121.673284431824 -0.496990193111001 0.619595957817724 FCGR3B other 1 1 1 -1.08970513156569 -0.496990193111001 0.00857952673696726 21.987007877757 7.07480734051203 3.10778892194762 0.00208619179916355 8.49876559634333 24.0095225108189 0.353974786150525 0.723634043659155 KLHDC9 other 1 1 1 3.10778892194762 0.353974786150525 0.0105017299394457 58.5166254867641 38.5737629085351 1.51700588883477 0.130443854629045 -258.13550048593 106.025513551056 -2.43465456417362 0.0155590604525523 C1orf74 other 1 1 1 1.51700588883477 -2.43465456417362 1.46762012233776e-09 160.903075907422 24.493843257558 6.56912327785768 2.56399391124683e-10 7.29467308468851 66.8093416477468 0.10918642370628 0.91313513563518 FLVCR1 other 1.57211467504821e-05 1 3.38036957258782e-06 6.56912327785768 0.10918642370628 0.0576647383233514 390.510749759111 175.517057290136 2.22491623200805 0.0269072985332426 582.29334418671 478.739858102322 1.21630429205302 0.224923469243994 ATF3 other 1 1 1 2.22491623200805 1.21630429205302 7.58463940877621e-07 41.9811757372524 12.0545285593564 3.48260618659099 0.000578096611503912 -19.3646922632585 17.9070344656041 -1.08140140683005 0.280472918113791 RBM15 other 0.00682086622031245 1 1 3.48260618659099 -1.08140140683005 0.00198239965650866 -24.9108652930861 47.3624980976267 -0.525961811425955 0.599341728121349 -213.940968774934 69.5990927091832 -3.07390456465973 0.00232670943051507 DENND2D other 1 1 1 -0.525961811425955 -3.07390456465973 0.596323474893691 3.89001544433775 4.75074342127577 0.818822466167436 0.413617937009692 10.1247101056059 14.7684011224628 0.685565757704545 0.493581781909487 AXDND1 other 1 1 1 0.818822466167436 0.685565757704545 0.0579994180228391 30.9875046959135 15.1526983581659 2.04501561130952 0.0418336758961895 -48.8696489543766 47.1044439989949 -1.03747427642749 0.300453527886494 TDRD5 other 1 1 1 2.04501561130952 -1.03747427642749 0.345568675260711 49.350237717908 78.877276378051 0.625658491063728 0.532069417720082 -316.280163761226 247.080720705105 -1.28006816095826 0.201623947537201 IER5 other 1 1 1 0.625658491063728 -1.28006816095826 0.152351019271945 -41.4945594181488 42.482083337752 -0.976754343431042 0.329565107106677 -130.275778334845 66.9323034150226 -1.94638121935014 0.0526461456582768 SNED1 other 1 1 1 -0.976754343431042 -1.94638121935014 7.88677639194006e-06 162.765641175073 35.921182661174 4.53118826042998 8.80393531552824e-06 -146.077594337814 100.97299361584 -1.44669964816114 0.149136708821001 BPNT1 other 0.0651999804321685 1 0.0908125927796738 4.53118826042998 -1.44669964816114 0.0520187291565704 11.7200793924095 4.83104453562387 2.42599282742815 0.015914808580302 7.54835670185273 13.2822399178492 0.56830449898055 0.570295371002033 SPATA17 other 1 1 1 2.42599282742815 0.56830449898055 0.0680440702642787 100.872460584925 43.9456483223288 2.29539133988999 0.0224719081215984 -15.9955373360384 122.087834590324 -0.131016635602661 0.895858997359144 C1orf115 other 1 1 1 2.29539133988999 -0.131016635602661 4.55239370417168e-05 182.343584066574 41.2387906668468 4.42165206879274 1.41720103577265e-05 -84.5079409463095 115.443482228442 -0.732028688974261 0.464781313373417 BROX other 0.349896980102636 1 0.143718357037704 4.42165206879274 -0.732028688974261 0.493585849419951 33.5944216721421 29.2993506952359 1.14659270171487 0.252655041397996 -28.4259384237231 98.7730884150983 -0.287790316976441 0.773747599272752 NBPF20 other 1 1 1 1.14659270171487 -0.287790316976441 0.146803694181907 43.6637894500672 22.5993920883053 1.93207805234116 0.0544663929941213 31.6511529640524 76.6170904840984 0.4131082603642 0.679877200648172 ACP6 other 1 1 1 1.93207805234116 0.4131082603642 0.454961116757178 0.186842668891133 58.9355189473454 0.00317028970353282 0.997472811470289 -198.888941012432 159.292089403553 -1.24858015082321 0.212896226910031 KIF26B other 1 1 1 0.00317028970353282 -1.24858015082321 1.14266686165323e-11 148.068648409247 20.0759943394202 7.37540795767745 2.03424464839529e-12 -8.81065105265538 54.3954669144495 -0.16197399438656 0.871447928152013 TFB2M essential 1.35246049745276e-07 1 2.84570483864017e-08 7.37540795767745 -0.16197399438656 0.00104533684295581 102.165920955812 28.0477222217578 3.6425746143677 0.000323782331007533 -36.5279606697098 75.9946889974746 -0.480664651064282 0.631145542583751 CNST other 1 1 1 3.6425746143677 -0.480664651064282 8.80062358612889e-17 148.877852952224 16.2278722864217 9.17420659495792 1.23484241610073e-17 -12.0737757943251 80.7363471202601 -0.149545727853413 0.881235087980192 PPP1R21 other 1.21642219207473e-12 1 1.85991964713093e-13 9.17420659495792 -0.149545727853413 0.82110519106424 -10.7196415358053 17.3752035978823 -0.616950556890845 0.537781518523431 2.91759708405272 49.6576504114453 0.0587542314201048 0.953190847133376 KLHDC8A other 1 1 1 -0.616950556890845 0.0587542314201048 0.828280464497291 -14.4858539892944 66.3937442949257 -0.218181007007937 0.827451082772066 -160.02590928408 268.282900483257 -0.596481956158316 0.551347589305351 PKDCC other 1 1 1 -0.218181007007937 -0.596481956158316 0.125034304365696 8.15789635899552 4.11220035230291 1.98382755218309 0.0482802427439126 12.3116489270671 16.4951827250193 0.746378450745699 0.456083438975513 OXER1 other 1 1 1 1.98382755218309 0.746378450745699 0.00510105416769186 21.1630166862812 8.02941510977663 2.63568596179727 0.0088788232703036 72.9525398461711 32.2082238373002 2.26502834228583 0.0242977847884189 HAAO other 1 1 1 2.63568596179727 2.26502834228583 5.1134650888754e-07 88.6493829276655 16.8297155614686 5.26743203733205 2.80904998254695e-07 -43.3683579019541 45.5826728144773 -0.951422003673731 0.342231754903685 B3GALNT2 other 0.00466603689359881 1 0.00323265471991503 5.26743203733205 -0.951422003673731 0.0228335640289525 207.897567383743 115.771606550686 1.79575608888803 0.073639056750001 -631.165496567129 329.599161585597 -1.91494873206228 0.0565439626984681 MAPKAPK2 other 1 1 1 1.79575608888803 -1.91494873206228 0.38757843239917 21.3555656644491 24.983520410283 0.854786087538701 0.393419082418712 -70.4541215102684 71.1275210392868 -0.990532503886273 0.322791019707063 IL24 other 1 1 1 0.854786087538701 -0.990532503886273 0.41826994561445 -29.4255186698261 22.2563012971582 -1.32212079073459 0.187234602861094 -6.64492751072797 63.3631895254746 -0.10487047070218 0.916555597914243 FCMR other 1 1 1 -1.32212079073459 -0.10487047070218 0.818981873917928 -212.683361298991 480.682904220821 -0.442460839425415 0.65850610571578 553.635894178068 1368.49342373382 0.404558680791844 0.686118717183219 PIGR other 1 1 1 -0.442460839425415 0.404558680791844 0.170620594127712 109.044131578088 297.304353055173 0.366776101518607 0.714072248844251 -1508.6450714902 831.53388324581 -1.81429175874512 0.0707385408492769 CAPN2 other 1 1 1 0.366776101518607 -1.81429175874512 1.84524435225499e-06 126.075802313948 24.627028514744 5.11940781805924 5.79278831112105e-07 -38.8476232010467 68.2511922703846 -0.569186001134567 0.569697910367692 MRPL55 essential 0.0160979117290725 1 0.00652325891715341 5.11940781805924 -0.569186001134567 9.28684061469931e-06 373.797070691048 78.6305125295288 4.75384248005089 3.24994320273888e-06 -152.048670178337 216.970491359768 -0.700780411315095 0.484043537398318 WDR26 essential 0.0763378298528283 1 0.0346898937460348 4.75384248005089 -0.700780411315095 0.0344942031276448 104.679287006465 40.2010828893005 2.60389222088158 0.00974720211435717 65.0578204528107 256.147861912579 0.253985412827745 0.799707568835425 REL other 1 1 1 2.60389222088158 0.253985412827745 2.06409286880553e-06 44.262387495049 8.49236792122837 5.21201953396371 3.80953217951318e-07 -27.9166439039047 53.7849968344463 -0.519041471543338 0.604173335478495 PUS10 other 0.017916326101232 1 0.00434553335717069 5.21201953396371 -0.519041471543338 8.15679310142621e-15 255.867233914694 30.4599619117608 8.40011667302518 2.93177155826775e-15 371.536599106788 192.913092107819 1.92592734400389 0.0552037908808708 PEX13 other 1.07212888525146e-10 1 4.30237476175792e-11 8.40011667302518 1.92592734400389 0.000113444938770557 61.3214825527472 14.4605065463718 4.24061787573639 3.10460627578893e-05 91.224679326431 91.496428047054 0.997029952683145 0.319680544460409 KIAA1841 other 0.83503444828725 1 0.305834764227968 4.24061787573639 0.997029952683145 0.286843753204221 30.9251717272274 19.7692060339962 1.56431025474907 0.118907387734249 -3.41642442342788 55.6996729255002 -0.0613365257637587 0.951136246842878 TRIM17 other 1 1 1 1.56431025474907 -0.0613365257637587 0.619018931998826 3.58262467453296 6.03031213549722 0.594102692204598 0.55294272312641 -8.86159484745359 15.0283728378711 -0.589657639123953 0.555915132078484 RFTN2 other 1 1 1 0.594102692204598 -0.589657639123953 0.322313037053613 -2.24244578564821 18.382253342274 -0.121989711701515 0.902996913845277 -77.8859551436936 51.6836181157538 -1.50697567204477 0.132973147092661 DISC1 other 1 1 1 -0.121989711701515 -1.50697567204477 0.293850662754014 7.55040746034111 88.84875763706 0.0849804506123081 0.932339447824079 532.331964444616 339.828241986531 1.56647358481087 0.118400408691017 CAPN13 other 1 1 1 0.0849804506123081 1.56647358481087 0.406136389514776 8.77768456071593 6.70755309732322 1.30862692152506 0.191798819554557 -5.8086762787695 28.2309791860514 -0.20575539518089 0.837140557954579 LRRTM1 other 1 1 1 1.30862692152506 -0.20575539518089 4.67652270709104e-06 100.379830322163 19.8118752553346 5.0666496244536 7.50104812412317e-07 28.9220877138589 75.9141106226907 0.38098434502655 0.703513358558784 MEMO1 other 0.0394055422916982 1 0.00838692190758212 5.0666496244536 0.38098434502655 5.10984061726691e-09 325.435461822487 50.8219213611234 6.40344664480614 6.6740114079451e-10 51.7762197356182 194.736788443445 0.265877958394363 0.790535360726728 DPY30 other 5.29992668822924e-05 1 8.67354522576545e-06 6.40344664480614 0.265877958394363 1.2090435039099e-21 79.8782817083711 8.02926770111999 9.94838940258885 4.86637171551223e-20 -19.6745355168066 18.5664422845422 -1.05968258297859 0.290246702789803 TYW5 other 1.80232115127848e-17 1 7.45284828230698e-16 9.94838940258885 -1.05968258297859 2.79616828506709e-24 143.925282615499 13.1979725293715 10.9051054845886 3.81954072364604e-23 -16.0469496269811 30.5182744380748 -0.525814447980742 0.599453570501315 MAIP1 other 4.26331778424179e-20 1 5.93518433047359e-19 10.9051054845886 -0.525814447980742 0.760727969440123 0.0626171310053616 2.87390458651085 0.021788173239733 0.98263290309904 6.36236554639434 8.90747311943424 0.714272775352305 0.475671032057381 KCNF1 other 1 1 1 0.021788173239733 0.714272775352305 1.21212428421414e-05 120.107388568756 26.1464448689969 4.59364128356787 6.67886585622485e-06 -14.8622079170934 80.739783563683 -0.184075399525576 0.854091967112769 PQLC3 other 0.0985820680351363 1 0.0695871033560067 4.59364128356787 -0.184075399525576 1.99464845576181e-05 227.38705071699 59.2088281619967 3.84042477744795 0.000153222735774267 -164.059019802595 134.286062925088 -1.22171293303993 0.222885755812051 ARL5A other 0.159172946769792 1 1 3.84042477744795 -1.22171293303993 0.00886732795291801 372.455542001688 165.217997900099 2.25432789850715 0.0249863631070351 -781.485060075915 516.200922667991 -1.51391643400558 0.131229863181324 FAM84A other 1 1 1 2.25432789850715 -1.51391643400558 0.605350317439252 15.2450339387684 18.7422849552252 0.813403166966479 0.4166957812966 -13.5893777608919 49.7581608532206 -0.273108521855915 0.784976280380741 KCNJ3 other 1 1 1 0.813403166966479 -0.273108521855915 4.72180475818355e-07 22.8751815172883 4.12773034069753 5.54183040780292 7.1767899362073e-08 2.28933061470118 19.6227153070107 0.116667371405183 0.907211353197396 CLHC1 other 0.00432092353421377 1 0.000854755681402289 5.54183040780292 0.116667371405183 5.78224235924804e-05 14.9635006058555 3.40251501619649 4.39777650785579 1.5830421694138e-05 21.3620628699722 16.7535746331168 1.27507492208533 0.203395283157524 PRORSD1P other 0.440317755656738 1 0.159950580797571 4.39777650785579 1.27507492208533 0.855486811089051 -24.8926630349547 49.6500345580504 -0.501362451336271 0.616524585898042 -51.1193718043897 126.863423730456 -0.402948070461996 0.687305302119924 FRZB other 1 1 1 -0.501362451336271 -0.402948070461996 0.0114974974309829 16.3346856407951 5.94326685119762 2.74843550689693 0.00639173751734068 -3.42635326592714 15.1859548054313 -0.225626462730002 0.82166264671014 DUSP19 other 1 1 1 2.74843550689693 -0.225626462730002 3.52509636606024e-10 190.598867256709 27.7278366070346 6.8739177151799 4.43352626311461e-11 40.0026540801824 136.528531924044 0.292998492816412 0.769751743810177 CFAP36 other 3.90369171577511e-06 1 5.98836392358891e-07 6.8739177151799 0.292998492816412 2.61787923226202e-14 91.6390223445191 11.9775309550748 7.65091091713622 3.57076844677741e-13 -19.5873763294615 30.5936994209138 -0.64024216424352 0.522560134771282 NUP35 other 3.39669830385998e-10 1 5.08334596083232e-09 7.65091091713622 -0.64024216424352 5.87152386176646e-07 60.4875829517009 11.3579026855504 5.32559440121404 2.12099325880245e-07 -0.488579124511837 38.2348422850588 -0.0127783742605566 0.989814046740223 CCDC138 other 0.00532714347467132 1 0.00245950378290732 5.32559440121404 -0.0127783742605566 0.00185639800435606 96.0032403829004 27.0415881879848 3.55020717405781 0.000453413400205606 -28.2232871553997 115.853156888361 -0.243612586082538 0.807714513457845 FBXO41 other 1 1 1 3.55020717405781 -0.243612586082538 0.30281460764589 -41.0849251458638 43.6980770316483 -0.940199842572204 0.347952340161349 226.442816436681 191.749158965491 1.18093251442857 0.238664923670019 ACTG2 other 1 1 1 -0.940199842572204 1.18093251442857 1.29263988836534e-10 82.9374157468248 11.8199442439264 7.01673493844453 1.80599840011658e-11 59.6934081163485 40.6219155112335 1.46948777193535 0.142856200386326 WDCP other 1.46223424171888e-06 1 2.46735501423927e-07 7.01673493844453 1.46948777193535 0.000174166690430782 279.122371263288 67.3308626508516 4.14553386477008 4.55218279202024e-05 14.8110173661451 220.295217981162 0.0672325868072705 0.946446673325987 SMC6 essential 1 1 0.441470687170123 4.14553386477008 0.0672325868072705 0.217297106721315 58.0896552948784 71.2286933551028 0.81553728643145 0.415489029615791 -312.669450947528 233.048262140115 -1.34165107294189 0.180844851700625 VSNL1 other 1 1 1 0.81553728643145 -1.34165107294189 0.0477848397120963 29.2416602962055 14.0325886598653 2.08383934033781 0.0381081812289655 -17.4888604116756 35.8337245563499 -0.488055892269132 0.625903441466306 CCDC74A other 1 1 1 2.08383934033781 -0.488055892269132 1.15880872765701e-06 619.18983345926 135.177997250282 4.58055190973743 7.09992801596395e-06 -795.601881748444 362.555936420253 -2.19442519574753 0.0290599744885623 H3F3A essential 0.0102751569881347 1 0.0738463512940411 4.58055190973743 -2.19442519574753 4.61290566023338e-06 227.270749852493 44.8274225093306 5.06990447209378 7.35338638828094e-07 68.3961622328827 124.234437412471 0.550541087136738 0.582398506525082 COQ8A other 0.0389052463384083 1 0.00822696869120872 5.06990447209378 0.550541087136738 0.00913815710057878 140.470198460037 46.2847680431942 3.03491201098699 0.00263906749696297 80.9024455048258 72.0613350487618 1.12268868527181 0.262559741583959 SLC16A14 other 1 1 1 3.03491201098699 1.12268868527181 0.262908511641756 -1.74182611978506 22.1523214165163 -0.0786295073565693 0.937385130262871 -108.927290125556 68.7069801257209 -1.58538899433856 0.114039854981273 EN1 other 1 1 1 -0.0786295073565693 -1.58538899433856 6.87938012091345e-10 212.074165636588 43.7067289821862 4.85220858607435 2.20893790055689e-06 -172.618902983151 88.6064087696459 -1.94815369881332 0.0525721343667476 SGCB other 7.5033398978803e-06 1 0.0238764097671194 4.85220858607435 -1.94815369881332 0.28221609345066 10.4199629171817 30.3375190847235 0.343467865255624 0.731549727069927 -74.9182079281877 61.5030838426172 -1.21812116153231 0.224384121741924 SPATA18 other 1 1 1 0.343467865255624 -1.21812116153231 0.624716388736128 -8.30965312238476 21.9252411929065 -0.378999393861775 0.704982912167279 38.548541683306 55.6919155770716 0.692174820777336 0.489415845603386 NOSTRIN other 1 1 1 -0.378999393861775 0.692174820777336 0.661509914939235 -13.8680117452104 15.2634327691581 -0.908577510377127 0.364377499971168 -10.5090996307818 46.2056421287383 -0.227441912862098 0.820250994051875 CFAP221 other 1 1 1 -0.908577510377127 -0.227441912862098 0.0100814438754145 -105.88721607286 124.964003409976 -0.847341739888651 0.397549619720742 -539.712775996852 184.006562247662 -2.93311700085148 0.00364160041557459 SGPP2 other 1 1 1 -0.847341739888651 -2.93311700085148 0.0501426830064259 143.512936722798 58.9960348323655 2.43258614126497 0.0156389294367285 190.347275219257 175.799274777512 1.08275347244837 0.279880311192595 INHBB other 1 1 1 2.43258614126497 1.08275347244837 7.19413900515011e-05 25.913878253743 8.80180956896747 2.94415347783796 0.00351708424471275 -49.1986342841766 23.684075503971 -2.07728751227498 0.0387099423850611 BBS5 other 0.541718667087803 1 1 2.94415347783796 -2.07728751227498 4.33593775184908e-14 181.606338981275 51.3782216256194 3.5346949200499 0.000480462333315391 -275.287303155481 75.2772182119902 -3.65698028824918 0.000306941388463453 SMARCAD1 other 5.59292610611012e-10 1 1 3.5346949200499 -3.65698028824918 0.130011124816923 -6.64137904150253 9.45574284537833 -0.702364600021734 0.483059128800394 -26.6416714074619 13.8541583380355 -1.92300901703421 0.0555345234461639 HPGDS other 1 1 1 -0.702364600021734 -1.92300901703421 7.29481176056883e-07 201.771129836067 147.383028543697 1.36902553726697 0.172133311951727 -704.832566887849 215.939439890921 -3.26402887422458 0.00124053328636323 PDLIM5 other 0.00656387162215983 1 1 1.36902553726697 -3.26402887422458 0.858542994679163 0.846095659586002 9.49073008390921 0.0891496915522328 0.929030284277803 -22.6096167632896 43.1073602666799 -0.524495506647059 0.600372396479979 NEURL3 other 1 1 1 0.0891496915522328 -0.524495506647059 4.19742564869927e-12 390.283030177749 52.1010723133487 7.49088287147893 1.03061849460656e-12 -202.740626992995 176.814146962619 -1.14663125363977 0.252572225085964 RPRD2 other 5.04740434256087e-08 1 1.4517292115028e-08 7.49088287147893 -1.14663125363977 2.52111472285507e-07 51.1137235310049 10.4555390092631 4.88867417411198 1.7577884063989e-06 -98.8761540825646 47.5210718498167 -2.08068021687406 0.0384201399341742 ANKRD23 other 0.00235209809793675 1 0.0191546202645288 4.88867417411198 -2.08068021687406 0.380963734243418 -63.592333329582 221.823654510826 -0.286679675663167 0.774580769395622 1182.30678257402 879.597212558142 1.34414566769204 0.180046541216384 CTSS other 1 1 1 -0.286679675663167 1.34414566769204 0.55553745177812 21.8997366108721 21.8103942877029 1.00409631857135 0.316227890825304 10.7970543972767 34.3610194495503 0.314223924966172 0.753592733674696 MSX1 other 1 1 1 1.00409631857135 0.314223924966172 9.68311832596031e-16 63.9849101946141 15.1076170416381 4.23527482979382 3.14091024598169e-05 -67.1710434783239 21.7659624090598 -3.08605896748057 0.00224076830776657 PACRGL other 1.30466498782887e-11 1 0.309348250126737 4.23527482979382 -3.08605896748057 0.78961054320624 -20.5451175659438 30.215150245976 -0.679960794458732 0.497120618061179 7.85069953479903 119.634725952563 0.0656222469879856 0.947727868580881 BNIPL other 1 1 1 -0.679960794458732 0.0656222469879856 0.123768788412205 0.145740261775876 18.9030554508842 0.00770987855135655 0.993854161321134 -42.3489189703629 27.6246521618394 -1.53301184471975 0.126443806584471 C1QTNF7 other 1 1 1 0.00770987855135655 -1.53301184471975 0.376279325201432 -0.633885063383184 6.5109777132211 -0.0973563558812413 0.92251671837149 35.8350876287808 25.7797504915001 1.39004788431122 0.165676451734994 TNFAIP8L2 other 1 1 1 -0.0973563558812413 1.39004788431122 4.39794625932378e-22 107.392958015013 9.93351075457854 10.8111785116369 8.0319219588513e-23 -34.1766203937903 39.3310252372187 -0.868948118887307 0.385658861621623 LYSMD1 other 6.58768370184109e-18 1 1.24510854206113e-18 10.8111785116369 -0.868948118887307 3.2332043067903e-27 506.511978291424 41.2290772463903 12.2853095950812 8.87046060387961e-28 -211.683618966464 163.243582027391 -1.29673470979671 0.195846214819078 VPS72 essential 5.00888011207953e-23 1 1.39417029311176e-23 12.2853095950812 -1.29673470979671 6.00984428203389e-12 235.147214090716 40.5450932870599 5.79964664098488 1.8473707207158e-08 -292.111609051738 110.31974851999 -2.64786326084498 0.00857491680487796 ERCC3 other 7.18056194817409e-08 1 0.000226321386994893 5.79964664098488 -2.64786326084498 6.65201014646396e-09 353.246943448295 57.274430358511 6.16762037155385 2.49928083459387e-09 -49.0689797064136 220.642140978755 -0.222391694935276 0.824175872964088 RNF149 other 6.85223565187252e-05 1 3.18133457435454e-05 6.16762037155385 -0.222391694935276 1.34421534566474e-08 182.209017749787 41.0197468142957 4.44198299357338 1.29962038427617e-05 -294.987567000332 111.001666776175 -2.65750574354119 0.00833959339512408 IWS1 other 0.000135819518525965 1 0.1322363741001 4.44198299357338 -2.65750574354119 1.67754634815095e-05 104.115952298391 21.833720424881 4.76858502684427 3.03291622800744e-06 62.9235649995803 95.8073629996682 0.656771703442022 0.511885053024149 BOLA3 other 0.134824400000892 1 0.0324673682208197 4.76858502684427 0.656771703442022 0.0280758934535395 303.515457899406 114.03016737188 2.66171193899567 0.00823704550812958 -92.6158797615158 421.170709294736 -0.219901046577061 0.826113166266452 CDC42EP3 other 1 1 1 2.66171193899567 -0.219901046577061 0.0394103741745628 1737.75982447866 747.810660709309 2.32379653805734 0.0208762539690936 -2754.96318980609 3129.39514173646 -0.880350056489638 0.379449732963543 S100A11 other 1 1 1 2.32379653805734 -0.880350056489638 0.71682525985837 -1.27299312194894 14.9992338888263 -0.0848705428146739 0.932426744463043 -46.2260113022545 56.6285799090076 -0.816301792779047 0.415041864651977 LCE3D other 1 1 1 -0.0848705428146739 -0.816301792779047 0.57980928103411 -188.064221129187 183.662395840367 -1.02396693818938 0.306760696453603 95.6183149713717 668.895274460705 0.142949604552766 0.88643581931741 IVL other 1 1 1 -1.02396693818938 0.142949604552766 0.988753165374522 62.2289829660837 886.336297234193 0.0702092232488603 0.944078723795504 425.016191635099 3092.32835337419 0.13744212873492 0.890783017245352 SPRR3 other 1 1 1 0.0702092232488603 0.13744212873492 7.84326218825716e-12 165.603647554463 23.0124261556323 7.19627067717635 6.03299659295169e-12 218.277532066843 84.7346130966128 2.57601379282829 0.010522795146492 DHX57 other 9.33661930890133e-08 1 8.3424276887336e-08 7.19627067717635 2.57601379282829 0.570525568018859 405.561279782038 407.960089686688 0.994119988780051 0.321047997016454 -429.494923728408 1410.50408330211 -0.304497469247253 0.76098175876704 SPRR2D other 1 1 1 0.994119988780051 -0.304497469247253 0.186203865822577 -34.530333211792 21.2026389793616 -1.62858657572783 0.104558208101692 -68.3635357693342 72.3994740556725 -0.944254591086741 0.345877552061469 PGLYRP4 other 1 1 1 -1.62858657572783 -0.944254591086741 0.659021600514618 2.56286688394012 21.7409870062556 0.117881809285048 0.906248953434006 -101.186760296753 112.376118025207 -0.900429397944283 0.36869419895902 ARHGAP25 other 1 1 1 0.117881809285048 -0.900429397944283 0.574979278649835 -3000.77982261877 5602.05452768287 -0.535657017936945 0.592633328617149 -17843.1249668867 19089.2914228739 -0.934719082632162 0.350762157642951 S100A9 other 1 1 1 -0.535657017936945 -0.934719082632162 0.793089809961966 -25.6117819715385 38.64508864986 -0.662743517128181 0.508056033813656 15.9271613703072 131.68514437954 0.12094880895906 0.90382087974957 S100A12 other 1 1 1 -0.662743517128181 0.12094880895906 0.879171667185601 11.3354306213391 93.0559857742667 0.121813019624942 0.903136718265831 210.45254577266 421.928014398741 0.498787799318233 0.618330537423316 TGFA other 1 1 1 0.121813019624942 0.498787799318233 0.753861842878606 2.60296975955525 3.661348123902 0.710932058757962 0.477733280744056 3.51428410980531 12.5619624605257 0.279755979278595 0.779876570508564 TDRD10 other 1 1 1 0.710932058757962 0.279755979278595 0.000252773744958343 93.9974446355086 51.5918659270011 1.82194310956902 0.0695740081743918 -220.65964089251 89.7730675722056 -2.45797149256408 0.0146033457554392 FZD5 other 1 1 1 1.82194310956902 -2.45797149256408 3.44261768144179e-11 262.346184281949 57.398877375113 4.57058040643312 7.40960414010849e-06 -98.8340807011971 82.6394469705047 -1.19596735365947 0.232758540030851 DCAF16 other 3.99619060461763e-07 1 0.0769042813701861 4.57058040643312 -1.19596735365947 0.250878222786551 96.0189790029117 86.8361286234781 1.10574919132163 0.269808575759592 -63.0600235871793 134.738251928768 -0.468018715431435 0.640144623608603 NPPC other 1 1 1 1.10574919132163 -0.468018715431435 2.56464009907722e-13 32.2005424458484 21.5805997573564 1.49210600297945 0.13688371182789 -163.032626998347 32.8207007585695 -4.96737190950376 1.23098937609297e-06 GNPDA2 other 3.22734310067877e-09 0.0192415949377092 1 1.49210600297945 -4.96737190950376 0.53228728480599 -49.3121367769356 84.5675648301906 -0.583109338384676 0.560301064843344 -145.366919104879 129.308690978736 -1.12418521914188 0.26192196423211 ALPP other 1 1 1 -0.583109338384676 -1.12418521914188 1.60135806366743e-11 273.878561696109 68.640365079489 3.99005106366996 8.50750607894073e-05 -281.799098562735 108.027805420072 -2.60857931406589 0.00959653941278409 PAQR3 other 1.88591939158113e-07 1 0.803533949155952 3.99005106366996 -2.60857931406589 6.13398075134472e-05 63.7199173454015 23.8892196457355 2.66730844666901 0.00813559426180347 -48.2199444615995 39.3267632827013 -1.22613559918393 0.221278725327383 NIPAL1 other 0.465929249178399 1 1 2.66730844666901 -1.22613559918393 0.00363318092488015 140.403762243027 79.6434338852304 1.76290442781955 0.0790478638910511 -156.456419862043 124.210657619538 -1.25960543853874 0.208899470373576 ANTXR2 other 1 1 1 1.76290442781955 -1.25960543853874 2.73156172221652e-25 43.3966735966735 8.7527367442086 4.95806910054592 1.25971999222644e-06 -73.4996534996536 13.2460154894189 -5.54881228686211 6.86187901488683e-08 HELQ other 4.18994252570792e-21 0.00108548064136495 0.0138707768344053 4.95806910054592 -5.54881228686211 1.10755400728073e-16 105.529937629938 20.4323503584882 5.1648457362174 4.67851451522639e-07 -89.8920073920073 30.9214406011751 -2.90710929517919 0.003950654164516 MRPS18C other 1.52632017743357e-12 1 0.00530169264865455 5.1648457362174 -2.90710929517919 0.000117225656996828 130.540524851372 94.1740511285076 1.3861623588141 0.167113484818417 -602.955048007959 195.364287433329 -3.08631150518606 0.00228928079824867 CGGBP1 other 0.861139676298702 1 1 1.3861623588141 -3.08631150518606 0.873363463826985 -12.540179000848 41.0840546352215 -0.305232263762431 0.760424433024317 36.1375123516707 119.119644699951 0.303371559264611 0.761840345850907 GPR155 other 1 1 1 -0.305232263762431 0.303371559264611 0.164931874864394 378.396271792086 240.759348158442 1.57167841949408 0.117183377150803 -272.861445136178 630.527721605316 -0.432750909732368 0.665537410356464 DAPL1 other 1 1 1 1.57167841949408 -0.432750909732368 0.00253683059987077 83.1723905901066 29.072530985754 2.86085826620539 0.00455406881203772 -178.391020147145 98.4477590574752 -1.81203738769714 0.0710871640072883 PMVK essential 1 1 1 2.86085826620539 -1.81203738769714 0.209521130318185 114.284546377328 127.958387344996 0.893138376847459 0.372575500680369 -635.246984536315 432.372184695583 -1.46921334679188 0.142934811085634 PBXIP1 other 1 1 1 0.893138376847459 -1.46921334679188 0.429662911659754 1039.63614705197 884.029685656721 1.1760194978969 0.240650501154746 4569.38275565993 6805.02508116378 0.671471846343068 0.502509336326417 CLDN1 other 1 1 1 1.1760194978969 0.671471846343068 1.33677981641447e-13 473.858065165108 59.9149125481843 7.90885015118773 6.62107306109278e-14 -283.631948826277 202.45286121384 -1.40097772452172 0.162364787112674 PYGO2 other 1.69744301088309e-09 1 9.52308938376975e-10 7.90885015118773 -1.40097772452172 4.7917184479066e-07 279.76930028769 121.237818549174 2.30760750758821 0.0217690623346161 -422.266307189987 178.193276502264 -2.36970953943159 0.0184976450129311 HIPK1 other 0.00438298486430017 1 1 2.30760750758821 -2.36970953943159 0.721857226200581 4.24221207877937 6.01805998251248 0.704913558706054 0.481471659500889 -7.00502490108412 20.1520734770291 -0.34760814608328 0.728405311056831 DCST2 other 1 1 1 0.704913558706054 -0.34760814608328 0.421315635523036 3.02660631255583 2.30834210352318 1.31116020798493 0.190921757935758 1.61296882956433 7.73112434867459 0.208633150473236 0.83489251943784 DCST1 other 1 1 1 1.31116020798493 0.208633150473236 0.1371653304174 -3685.87195068789 1901.61391465039 -1.93828616960112 0.0536191323911188 -4241.76640588521 3006.83570864732 -1.41070773959694 0.159469267209657 COL6A3 other 1 1 1 -1.93828616960112 -1.41070773959694 1.83437756966449e-12 453.639614451808 59.5070101943076 7.62329703627428 4.29855401502691e-13 -167.438362863625 196.564442849209 -0.851824269112969 0.395072160608084 YY1AP1 other 2.23940813704641e-08 1 6.10824525535324e-09 7.62329703627428 -0.851824269112969 0.188518887545816 1.32158298355792 10.8325885078907 0.122000663331321 0.902989245480136 -36.9569890210846 22.7473682038894 -1.62467098126831 0.105399426759928 KBTBD8 other 1 1 1 0.122000663331321 -1.62467098126831 1.01641298660602e-06 5.58875338753427 43.2262367866774 0.129290768824381 0.897223481265525 -440.649016203704 90.532931012436 -4.86727880425273 1.92348592357481e-06 EOGT other 0.00904099351586052 0.0299813750907606 1 0.129290768824381 -4.86727880425273 1.7697883997926e-08 893.331200839225 144.973124605378 6.16204695367438 2.56665685005607e-09 -2.40503815523046 475.849811481748 -0.00505419587693313 0.995971043576478 NAXE other 0.00017758056803519 1 3.26504417895633e-05 6.16204695367438 -0.00505419587693313 1.05897252865467e-07 132.726281875843 25.5353238217381 5.19775205524723 3.97556282536031e-07 -163.273788545903 97.1091329624882 -1.68134328425085 0.093848284941474 POGLUT1 other 0.00101301312091106 1 0.00452975628321553 5.19775205524723 -1.68134328425085 0.000413270486539069 24.8504939343452 20.3515318891825 1.2210625750268 0.223123595959295 -62.231189692168 29.7654039372957 -2.09072216265787 0.0374845649575552 SLC22A15 other 1 1 1 1.2210625750268 -2.09072216265787 0.549679132697479 -14.9376557052009 16.8655096425251 -0.885692518151763 0.37656271183089 -34.3396517072459 46.4342847194482 -0.739532264031264 0.460219280776702 IGFN1 other 1 1 1 -0.885692518151763 -0.739532264031264 4.07542903216776e-10 3267.20968176487 1184.5797822052 2.75811703934595 0.0062090856252849 -6895.13496532147 2016.84236769036 -3.41877733023707 0.000725798459426051 ATP1A1 other 4.50049628022286e-06 1 1 2.75811703934595 -3.41877733023707 0.0162767194918603 88.8170803798831 40.5050236493537 2.19274234101824 0.0291792793929669 -237.337082810782 158.855272451169 -1.49404599009289 0.136331318539975 SLC15A2 other 1 1 1 2.19274234101824 -1.49404599009289 0.0700396388923393 -41.2680970568414 59.8169262485043 -0.689906681018623 0.490841072051625 -294.625372575452 128.039682920011 -2.3010473460756 0.0221453656196784 EIF4E3 other 1 1 1 -0.689906681018623 -2.3010473460756 5.39985987349528e-18 477.183997828437 53.0138968163 9.0011115289627 4.03958739993196e-17 -344.942264821462 204.242327165101 -1.68888726254389 0.0923912426840976 LRRC58 other 7.65052146876811e-14 1 6.05332171879805e-13 9.0011115289627 -1.68888726254389 0.839331984915328 -12.4880242133088 46.4523771382991 -0.268834987198376 0.788259718545043 64.2455319354314 128.70394032768 0.499172999457998 0.618059524596958 LMOD1 other 1 1 1 -0.268834987198376 0.499172999457998 0.800594210707658 181.015092673029 424.02558637777 0.426896627204378 0.669791088000005 -541.653313818099 1158.99701811708 -0.467346598266557 0.640624728871113 ELF3 other 1 1 1 0.426896627204378 -0.467346598266557 0.187135355089792 0.824128308135785 3.32778438116081 0.247650753096061 0.804590796026223 -6.98590997766073 5.00559749304792 -1.39561960132895 0.16396314827253 TMEM169 other 1 1 1 0.247650753096061 -1.39561960132895 0.422002402604786 -167.264164173199 319.646324480874 -0.523278859673567 0.601225891006873 -920.809261431964 700.531031941504 -1.31444464191681 0.189854968252839 IGFBP7 other 1 1 1 -0.523278859673567 -1.31444464191681 0.024189297873849 13.8444316445869 5.07896743210753 2.72583587700662 0.00683495820420196 8.84883924770228 17.010532676487 0.520197657298156 0.603353666892174 TRIM46 other 1 1 1 2.72583587700662 0.520197657298156 1.66376831802531e-05 245.974660455953 53.6798186665991 4.58225580052126 7.0464742511854e-06 -195.752621188216 179.785029477375 -1.08881491277254 0.277210010175041 KRTCAP2 other 0.133750335086055 1 0.0733115181093329 4.58225580052126 -1.08881491277254 0.0230244203453388 -17.7556503716392 14.9370603609602 -1.18869777202251 0.235591590222616 -60.8680178560045 22.2061355629694 -2.74104504511389 0.00652867598220313 CXCR1 other 1 1 1 -1.18869777202251 -2.74104504511389 1.09895467730221e-16 761.965550445862 393.940767751586 1.93421349812251 0.054120205736956 -3787.82050228734 585.65084970371 -6.46771110159519 4.576767442938e-10 ARPC2 other 1.51468923172563e-12 7.29216356683311e-06 1 1.93421349812251 -6.46771110159519 3.8131094979211e-09 6.37142496980498 1.00486250635821 6.34059379217569 9.48669343877318e-10 -2.62551644210962 3.34918953081954 -0.783925907432048 0.433765702997045 TSACC other 3.98126762677943e-05 1 1.22662946163337e-05 6.34059379217569 -0.783925907432048 8.02030121629666e-15 2199.08184605823 262.122126758544 8.38953152582928 2.68750928838372e-15 -1001.9897483554 873.648561052905 -1.14690253383788 0.252429767898141 CCT3 essential 1.05442900090652e-10 1 3.947413642778e-11 8.38953152582928 -1.14690253383788 0.65231574322105 28.2772165480364 56.102417678534 0.504028484299276 0.614649365661631 -138.42489847051 186.988397670029 -0.740286029482875 0.459764969527277 TMEM79 other 1 1 1 0.504028484299276 -0.740286029482875 1.74548304308572e-10 1336.12133996744 196.717971794788 6.7920654517588 6.98332511012088e-11 -685.454732533879 646.072218835187 -1.06095682889708 0.289654132213973 SSR2 other 1.96174839212404e-06 1 9.37930395540336e-07 6.7920654517588 -1.06095682889708 1.73934886528072e-20 96.4886382670211 18.5648682529988 5.19737802348449 3.99225060320517e-07 -130.850245776859 27.6314979708743 -4.73554658219347 3.53262574297809e-06 RNF25 other 2.55736463662224e-16 0.0548369494082489 0.00454757266211101 5.19737802348449 -4.73554658219347 5.25746693142098e-08 69.6809456027483 42.7037973572702 1.63172715109574 0.103902742534464 -250.147105778924 63.5592924197259 -3.93564963132424 0.000105614004314483 STK36 other 0.000512392727136289 1 1 1.63172715109574 -3.93564963132424 0.675534196727074 3.11538334024036 6.49583709361875 0.479596901113913 0.631899446309897 14.5674816963669 18.5282304623966 0.786231676356351 0.43241618670701 ADORA1 other 1 1 1 0.479596901113913 0.786231676356351 0.734652416624881 6.72978395661011 9.05164855246395 0.743487102664652 0.457830907909002 0.479157227982488 23.6123222200765 0.0202926769979059 0.983824830188553 NEK10 other 1 1 1 0.743487102664652 0.0202926769979059 0.77218833228839 -1.72603749583648 6.05939885780909 -0.284852926229148 0.775976816643906 -11.6752613682897 16.2696798810798 -0.717608548762351 0.473623711559498 CCDC141 other 1 1 1 -0.284852926229148 -0.717608548762351 0.980896677676761 -0.865145754119131 8.11409294200924 -0.106622608380537 0.915167267580205 -4.0899450781581 21.3530911736999 -0.191538782131722 0.848246929899695 EOMES other 1 1 1 -0.106622608380537 -0.191538782131722 5.22093057992311e-17 172.127758274825 19.9642853125246 8.62178413002545 5.68530191166837e-16 -21.6663987689568 52.3579556591672 -0.413812924820783 0.679339628508701 CWC22 essential 7.25291676162918e-13 1 8.41936360098969e-12 8.62178413002545 -0.413812924820783 1.36118844907956e-06 143.359462357355 38.5861471858546 3.71530906329798 0.000246650086727118 -234.110970701116 101.442289957507 -2.30782419047502 0.0217651741791336 AZI2 other 0.0119961538017381 1 1 3.71530906329798 -2.30782419047502 0.521804181140619 -185.013103340375 420.206870259901 -0.440290524583625 0.660078972092448 -1249.51518944431 1095.0279566442 -1.14108062891249 0.254847439766375 TGFBR2 ts 1 1 1 -0.440290524583625 -1.14108062891249 3.02894855529052e-08 124.584245948954 68.081593097861 1.82992553904953 0.068363560171679 -391.966841408559 101.012415466342 -3.88038281828006 0.000131127542597695 ANKZF1 other 0.000299835617488209 1 1 1.82992553904953 -3.88038281828006 1.95084228507542e-09 144.998602318506 23.6735623175394 6.1249169167531 3.15198656638588e-09 -10.5409803867831 64.7032401971296 -0.16291271278947 0.870707687479472 HDAC11 other 2.07589127554876e-05 1 3.99829495946049e-05 6.1249169167531 -0.16291271278947 0.616460084766204 -1.19769605485982 2.91282280050301 -0.411180540969739 0.681265122972132 -10.9859073858003 11.4209788515148 -0.961905938941757 0.336954336528419 TRAT1 other 1 1 1 -0.411180540969739 -0.961905938941757 0.906801655461082 94.5769958069548 220.628987092876 0.428669854551532 0.668501541777976 149.884988169949 603.010656142074 0.248561093644479 0.803887186120671 FBLN2 other 1 1 1 0.428669854551532 0.248561093644479 6.595779741664e-09 34.4786412913747 19.0720091592989 1.80781379682612 0.0717482335565901 -117.274538008687 28.2970715771559 -4.14440546220202 4.56371979019295e-05 GLB1L other 6.79497228986225e-05 0.689806246287664 1 1.80781379682612 -4.14440546220202 6.99749144292905e-12 965.136429800187 133.76445414546 7.21519357265622 5.40967776822283e-12 -19.0344272418525 425.873014891897 -0.0446950771151448 0.964383273276007 STT3B other 8.34660779312577e-08 1 7.49023983788133e-08 7.21519357265622 -0.0446950771151448 7.0554571866358e-30 95.7082956507437 8.44173761940066 11.3375112998997 1.13463667099178e-24 -56.4752334036745 23.0724793143847 -2.4477314567778 0.0150059794968359 CHCHD4 essential 1.10474348628343e-25 1 1.77128130708527e-20 11.3375112998997 -2.4477314567778 0.695567551660214 2.3729540775769 3.10069318630289 0.765297930172282 0.444760122372766 6.33462055703993 12.2575020830089 0.516795388990457 0.60572048684937 DPPA2 other 1 1 1 0.765297930172282 0.516795388990457 0.23117923456942 40.6142134174325 28.9614399223559 1.40235476987046 0.161953792775142 92.4532804323803 83.4632332124548 1.10771266429425 0.268968114257319 NFASC other 1 1 1 1.40235476987046 1.10771266429425 0.720551098335872 7.30328372409304 9.0958179805622 0.802927646496466 0.422722782372533 -1.43489389148227 29.6391203086237 -0.0484121619178009 0.961423558055138 FCRL1 other 1 1 1 0.802927646496466 -0.0484121619178009 3.23290957829168e-14 147.126774036151 18.7934569424056 7.82861686846837 1.1743295392953e-13 -24.1950902229549 43.2248701240047 -0.559749286777343 0.576121498993569 SGO2 other 4.18435486718293e-10 1 1.68340139457981e-09 7.82861686846837 -0.559749286777343 0.985908309350559 -3.16993055093309 32.8807831341032 -0.0964067838045292 0.923272348136046 40.432140347763 299.728944784011 0.134895681753055 0.892799531738855 SERPINI1 other 1 1 1 -0.0964067838045292 0.134895681753055 1.04235248451094e-07 200.188846692446 38.3405729651336 5.22133163931834 3.55046316719431e-07 -139.613717173699 126.00319695425 -1.1080172610572 0.268840418573973 CLASP2 other 0.000997635562925425 1 0.0040599546316867 5.22133163931834 -1.1080172610572 1.04528626401876e-08 387.336257193096 64.3020667246198 6.02369841162187 5.65109329529511e-09 -273.738191336318 264.632559010887 -1.03440858660576 0.301884689992868 SUCLG1 other 0.000106389235951829 1 7.08986164827725e-05 6.02369841162187 -1.03440858660576 0.0298108938142791 72.1042505960701 36.3824006582272 1.98184422389854 0.048499489452185 -165.32732101912 103.979474130339 -1.58999958791752 0.112992235304293 NUAK2 other 1 1 1 1.98184422389854 -1.58999958791752 5.94173988124373e-33 491.181457535589 34.7517590718352 14.1340027283301 4.56503302329159e-34 255.728643902837 338.655034169042 0.755130200648926 0.450851735735517 PRKCI other 9.36180535688762e-29 1 7.23101230889388e-30 14.1340027283301 0.755130200648926 0.39411250920737 -12.1030034635394 26.202773675164 -0.46189779805682 0.644523824492826 114.76169769464 92.0434469846282 1.24682094656674 0.213535750950832 MNDA other 1 1 1 -0.46189779805682 1.24682094656674 0.299067425988494 2.56045422379569 3.47782327562379 0.736223212301217 0.462229318547552 17.41138921343 12.2166777555766 1.42521474019253 0.155241605543874 PYHIN1 other 1 1 1 0.736223212301217 1.42521474019253 0.000509064580660563 838.355638804704 247.862728707164 3.38233845474676 0.000824320108953571 -1525.06575272448 859.370942284693 -1.7746303460878 0.0770773890262605 IFI16 other 1 1 1 3.38233845474676 -1.7746303460878 0.327518377768689 34.6712619345276 25.647098520338 1.35185903805195 0.177543470378584 -47.878829324809 88.9216839387364 -0.538438176202282 0.590714925316382 AIM2 other 1 1 1 1.35185903805195 -0.538438176202282 0.00829111287392216 2.79414133485898 6.86536142351156 0.406991149117071 0.684336941894312 -48.2509381713187 17.4140819668296 -2.77079999182428 0.00598028136234895 EFHB other 1 1 1 0.406991149117071 -2.77079999182428 1.79876923534062e-10 82.9849459973227 11.9164899686955 6.96387495104041 2.66249665345331e-11 -71.1734270232433 111.854780807913 -0.636302056194352 0.525135044941821 EIF5A2 other 2.02055748205811e-06 1 3.61993045003512e-07 6.96387495104041 -0.636302056194352 5.43904725424193e-13 251.39748358629 32.4723507175232 7.74189358119451 2.16007054361692e-13 620.59872148325 309.838737237836 2.00297331126441 0.046214186053113 RPL22L1 other 6.7694382126295e-09 1 3.08587677861113e-09 7.74189358119451 2.00297331126441 0.000999172274353179 122.364450817777 32.6279348179632 3.75029714569643 0.000219159155463463 99.1306808229386 208.22063542548 0.476084806005773 0.634426445105141 PPM1L other 1 1 1 3.75029714569643 0.476084806005773 0.00178813807173118 49.3555354464289 13.8654119377492 3.55961551434734 0.000438962323962153 17.7156759248414 31.8163401758396 0.556810614512294 0.578119777472743 ICA1L other 1 1 1 3.55961551434734 0.556810614512294 8.22037997445888e-13 565.931767118388 72.6789591582658 7.78673461580558 1.46338776030066e-13 146.207294899968 161.744875164585 0.903937727555159 0.366831254574621 SNHG16 other 1.01653218764159e-08 1 2.09381520743819e-09 7.78673461580558 0.903937727555159 0.120164914380111 -14.9959692773867 7.27770541595926 -2.06053535012588 0.0403125033604508 -12.0590891782187 15.5925808313738 -0.773386350125864 0.439975380519487 CTLA4 other 1 1 1 -2.06053535012588 -0.773386350125864 0.41723558670139 -7.24608521765887 5.62800175666752 -1.28750585571058 0.199028759273498 -1.20861405937549 11.89027420105 -0.101647282387211 0.919112655401254 ICOS other 1 1 1 -1.28750585571058 -0.101647282387211 0.000380354261516968 145.890527648892 69.885897220959 2.08755318956024 0.0377687309079281 -340.533419522144 149.294523732824 -2.28095050647376 0.0233247902037892 RYBP other 1 1 1 2.08755318956024 -2.28095050647376 0.000127639334083296 171.553905069183 54.8858873011067 3.12564692865453 0.00196630084002174 -165.867056903462 117.250586028317 -1.41463733804626 0.158318572842407 PPP4R2 essential 0.933171171482979 1 1 3.12564692865453 -1.41463733804626 0.526136547859313 1.21146423044079 4.87101116097866 0.248708982674017 0.80377427588397 -18.849975557958 18.2320409972553 -1.0338927803418 0.302108027990621 CD200R1 other 1 1 1 0.248708982674017 -1.0338927803418 1.17319431705448e-14 99.1433237302854 11.98435905183 8.27272641795108 5.89844640944222e-15 -11.5422517316241 44.8857994015208 -0.257147068460878 0.797259659185357 GTPBP8 other 1.53618063875114e-10 1 8.62352865060452e-11 8.27272641795108 -0.257147068460878 4.91630829217149e-26 333.577758977271 28.77893628695 11.5910385168938 1.62949217583271e-25 -98.7943045218356 107.787621814279 -0.916564470566581 0.360182832554561 NEPRO other 7.57553944740705e-22 1 2.54901461065511e-21 11.5910385168938 -0.916564470566581 5.98185372273176e-15 113.340378924208 15.1645267985797 7.47404653172714 1.05913879331514e-12 -160.298729369364 58.1765281240295 -2.75538493853767 0.00625677090028508 SPICE1 other 7.89724328475047e-11 1 1.49116150710838e-08 7.47404653172714 -2.75538493853767 4.05862061567165e-07 45.4086648087154 9.93978656669433 4.56837423057635 7.46033729902954e-06 -85.4933927166537 37.119823919239 -2.30317344453628 0.02202369539103 CCDC191 other 0.00373474269054105 1 0.0774084598147305 4.56837423057635 -2.30317344453628 0.714437708896007 28.1733234561806 41.7300624828639 0.675132549052611 0.500167167476846 61.2692278672893 88.1206269396127 0.69528815210627 0.487470487542681 CADPS other 1 1 1 0.675132549052611 0.69528815210627 0.00356030766382502 15.2328019931835 4.90913638245092 3.10294944089095 0.00211939865759333 6.18739171056733 7.49287651656891 0.825769875812744 0.409663691394498 NKX6-1 other 1 1 1 3.10294944089095 0.825769875812744 1.03812205242299e-13 175.859371778731 48.7398433620143 3.60812344989578 0.000367418874963605 -265.561269338574 74.3922350688808 -3.56974446449535 0.000422819713130269 CDS1 other 1.32267130699213e-09 1 1 3.60812344989578 -3.56974446449535 6.17971846327665e-14 176.744110151462 60.5603941163454 2.91847688130811 0.00381372296498914 -397.217912333261 92.434090144787 -4.29730970155131 2.4156102882906e-05 WDFY3 other 7.93043270392292e-10 0.368066539626838 1 2.91847688130811 -4.29730970155131 1.562003458148e-27 132.581685268181 14.9948627420634 8.84180719415753 1.26628258845207e-16 -108.730441973134 32.4068969718907 -3.35516362666396 0.00090741921538042 COX18 other 2.423135964625e-23 1 1.88916699371165e-12 8.84180719415753 -3.35516362666396 4.07293034195106e-12 620.818913013338 185.682139919205 3.3434497969674 0.000944090596690539 -937.061591361133 283.63956120024 -3.30370554585508 0.00108256123316305 PTPN13 other 4.90014249440132e-08 1 1 3.3434497969674 -3.30370554585508 0.796617096482984 21.0297651362323 58.4080283167842 0.360049221695593 0.719093901124829 78.3176228746553 116.115506708891 0.674480309257939 0.500587393121007 ALB other 1 1 1 0.360049221695593 0.674480309257939 0.000542418119779947 167.640903759492 52.3212055888417 3.20407188391019 0.00151697286229359 -91.4676831903201 110.485754499371 -0.827868566448004 0.408473378470292 THOC7 essential 1 1 1 3.20407188391019 -0.827868566448004 5.5156408556465e-06 69.4553984813876 38.7475965695635 1.79250855873588 0.0741668206037685 -295.504022882071 81.8226069878338 -3.61152050466945 0.000362630811006269 ATXN7 other 0.0461493670391942 1 1 1.79250855873588 -3.61152050466945 1.04499704136773e-10 230.415210815483 46.1199578396819 4.99599786314706 1.05071460784444e-06 -256.166471181349 97.3906904867484 -2.63029730974342 0.00901900096030253 PSMD6 essential 1.18732563840201e-06 1 0.0116356135672693 4.99599786314706 -2.63029730974342 0.103001259303839 11.2021318188363 56.3524189689879 0.198787062273247 0.842578370378462 -223.682422097386 118.998395728502 -1.87970956018369 0.0612204734947053 PRICKLE2 other 1 1 1 0.198787062273247 -1.87970956018369 0.835374858163321 27.8980389735993 65.4538403840421 0.426224631128 0.67028251800985 -30.3294579226431 138.217704625188 -0.219432510508614 0.82647833260327 ADAMTS9 other 1 1 1 0.426224631128 -0.219432510508614 3.28951202096002e-06 -2.01750569712047 37.0493259116195 -0.0544545858117146 0.956612964977181 -233.403196037441 57.3950485190664 -4.06660856746041 6.25204269401418e-05 PPM1K other 0.0280398004666632 0.940057139471972 1 -0.0544545858117146 -4.06660856746041 1.73045831119752e-16 618.936705091259 67.765402582301 9.13352066844967 1.86054648338709e-17 31.462695485111 460.181981416847 0.0683701160750384 0.945543159131063 GMPS essential 2.37366966546964e-12 1 2.7978898017175e-13 9.13352066844967 0.0683701160750384 0.00579814584277042 161.199231508166 49.9041729062337 3.2301753965755 0.00139516130995395 154.322756964458 338.889762236247 0.455377453559297 0.649214862025888 TIPARP other 1 1 1 3.2301753965755 0.455377453559297 5.8498913226359e-06 403.517589118198 83.1892776055851 4.85059614330762 2.11410267261145e-06 -578.000107209864 565.936700346384 -1.02131582358256 0.308046942074466 CCNL1 essential 0.0488231929787192 1 0.0228915037390368 4.85059614330762 -1.02131582358256 0.776308472556526 1.60066467317592 13.3239041567326 0.120134808412525 0.904468783297741 -61.9171220761917 89.2523887027199 -0.693730699829492 0.488468050587958 PTX3 other 1 1 1 0.120134808412525 -0.693730699829492 5.12636233555176e-05 5.72134890419681 2.35557914804895 2.42885020821126 0.0157926359286763 -15.9808527503935 5.61208014652281 -2.84758099192419 0.00474004945350356 HESX1 other 0.392313489777369 1 1 2.42885020821126 -2.84758099192419 4.20451823418439e-07 143.838021525305 43.8573657563312 3.27967763327283 0.00117417303780847 -336.560528754366 104.488550870285 -3.22102781549896 0.00143197340789488 SLMAP other 0.00386418147063002 1 1 3.27967763327283 -3.22102781549896 0.0864781456091121 147.835601021369 183.911843429005 0.803839482357412 0.422194217004781 -330.439875677179 296.036762225826 -1.11621230144758 0.265320001236377 RPL9 essential 1 1 1 0.803839482357412 -1.11621230144758 8.46751949855907e-10 -93.5170510239874 114.725831431226 -0.8151350908278 0.415710775513197 -1056.15368309379 184.670345570631 -5.71912983554712 2.82537231426315e-08 SMIM14 other 9.18810540788645e-06 0.000448132302765279 1 -0.8151350908278 -5.71912983554712 5.76967449602986e-17 160.338470899531 19.4770580078424 8.23217093849445 7.64705037367437e-15 -66.3392021793248 46.4033699096974 -1.42962035534107 0.153969362177319 RPP14 essential 8.00830820048944e-13 1 1.11578112002283e-10 8.23217093849445 -1.42962035534107 0.874382817453836 13.5727958333798 46.6148396208798 0.29116899132911 0.771143173146178 -34.8421217162193 111.058130305816 -0.313728689833657 0.753966690624462 ABHD6 other 1 1 1 0.29116899132911 -0.313728689833657 0.991778273941739 -6.15228203954497 48.1858454351757 -0.127678200599834 0.898497639479608 -3.08917147673877 114.80099351964 -0.0269089263257141 0.978552033352166 DNASE1L3 other 1 1 1 -0.127678200599834 -0.0269089263257141 0.0590594495182534 51.7336578503725 21.8212990096699 2.37078726740545 0.0184449145776006 23.9076577833842 51.9884373424421 0.459864904688462 0.645979210468799 C3orf67 other 1 1 1 2.37078726740545 0.459864904688462 5.26766355812985e-06 229.685336624483 114.043946414209 2.01400726514902 0.0450042386995492 -358.552610283353 165.931445776105 -2.16084786464861 0.0315898528960678 RBM47 other 0.0441482882806862 1 1 2.01400726514902 -2.16084786464861 4.1712793179209e-06 19.9191009227955 92.0638501356715 0.216361806435874 0.828869719522013 -494.306372389742 133.576258766228 -3.70055559989017 0.00026088170344758 APBB2 other 0.0352973655882466 1 1 0.216361806435874 -3.70055559989017 1.32373184302241e-08 239.01710347078 38.8487423355801 6.15250556648969 2.71760510192754e-09 104.593383161076 108.004338682533 0.968418347234333 0.333695783884588 IL17RE other 0.000133802814692705 1 3.4540760845499e-05 6.15250556648969 0.968418347234333 1.20951268075281e-12 222.042631929345 30.6130361087885 7.25320517508552 4.24523620175813e-12 -41.2532846926612 85.1080503825233 -0.484716598573763 0.628267498979282 IL17RC other 1.48564442576867e-08 1 5.89578403700169e-08 7.25320517508552 -0.484716598573763 2.04776208515868e-05 137.96844554809 37.9901757115197 3.63168748140994 0.000336434679256571 -187.668360728065 105.617416613202 -1.776869447729 0.0767072857963767 CRELD1 other 0.16324759342885 1 1 3.63168748140994 -1.776869447729 0.000634532444612229 29.4911184576966 9.35288473901064 3.15315747821524 0.00179603877822498 -31.0251705829777 26.0021836044263 -1.19317558305743 0.23384032735393 PRRT3 other 1 1 1 3.15315747821524 -1.19317558305743 5.28382040745683e-16 16.7364015094023 2.00872130538651 8.33186837045171 3.91624279518369e-15 -3.09157424804647 5.5886482279421 -0.553188198997609 0.580587266006117 FANCD2OS other 7.16591723659295e-12 1 5.73964544062122e-11 8.33186837045171 -0.553188198997609 0.0260204049592938 44.0006212961193 18.8033562114609 2.34004083107783 0.0200130739760533 -112.689659017748 103.628615110841 -1.0874376628233 0.277816820952717 PCOLCE2 other 1 1 1 2.34004083107783 -1.0874376628233 1.05668509178774e-11 665.390588160328 90.1415576538205 7.38161848407028 1.95686086081553e-12 -69.7648695406331 496.786035351808 -0.140432428804541 0.888423433843657 U2SURP essential 1.25238317078682e-07 1 2.73823540253917e-08 7.38161848407028 -0.140432428804541 1.79480328023706e-13 186.839293299968 26.7833785883307 6.97594191426515 2.32664534489149e-11 -128.352222872708 74.0465960760877 -1.73339801792938 0.0841623650683104 MTMR14 other 2.26970822818778e-09 1 3.16772763706976e-07 6.97594191426515 -1.73339801792938 1.88929127227614e-06 78.811432281119 14.9621995556837 5.26736941235228 2.91236866331781e-07 25.9912213349085 165.033420484929 0.157490654065926 0.874980881648219 TTC14 other 0.0164689520204311 1 0.00334776777848382 5.26736941235228 0.157490654065926 0.181687541506914 -24.5688622228751 32.2326378257497 -0.762235543851388 0.446589745242791 -117.914567137568 64.0786751677695 -1.84015301235312 0.0668514645299006 CXCL3 other 1 1 1 -0.762235543851388 -1.84015301235312 0.896174614550093 -49.6999733970711 126.474895744563 -0.392963149757786 0.694659089652088 -105.780117281163 251.432842856536 -0.420709228275001 0.674304579125673 CXCL5 other 1 1 1 -0.392963149757786 -0.420709228275001 0.433193557378229 -3.26958395536092 8.43160452493478 -0.387777195395228 0.698488733242316 -21.1098671697322 16.7620798029993 -1.25938233308941 0.20898799025861 PPBP other 1 1 1 -0.387777195395228 -1.25938233308941 1.94678036675592e-13 123.324788105769 17.0862591565277 7.21777581482215 5.44810514032082e-12 19.9100595653916 33.9675845409342 0.586148819071845 0.558268839100107 MTHFD2L other 2.45956231535943e-09 1 7.54181194574611e-08 7.21777581482215 0.586148819071845 0.0391092332437003 -395.200674760317 320.37596063835 -1.23355283577731 0.218450339360601 -1630.31530909296 636.909309883001 -2.55972912280469 0.011024539204153 CXCL1 other 1 1 1 -1.23355283577731 -2.55972912280469 5.83465528316895e-21 134.350807387454 18.5402117412206 7.24645485513798 4.53000368110508e-12 -104.243095946418 36.5694452795872 -2.85055174201961 0.00470232239735413 RCHY1 other 8.6335394225051e-17 1 6.28356810606086e-08 7.24645485513798 -2.85055174201961 0.785376379938738 -3.16264675394959 30.0517941340611 -0.105239864875988 0.916264792886244 -128.230706551023 184.579964241287 -0.69471628233386 0.487839479220624 CPA3 other 1 1 1 -0.105239864875988 -0.69471628233386 1.03689810182423e-05 207.536518542762 43.1297828008026 4.81190734257304 2.50819773590471e-06 -101.709512151637 264.802149305537 -0.384096248532639 0.701213968741965 GYG1 other 0.0848078957482039 1 0.0270208142089014 4.81190734257304 -0.384096248532639 0.0166321119166373 291.704352554241 101.412569891139 2.87641219295962 0.00434682757847187 330.875751191675 628.777961821713 0.526220337355738 0.599171950242577 HPS3 other 1 1 1 2.87641219295962 0.526220337355738 0.591195580559446 3.43340644618412 6.15807549970564 0.557545364026187 0.577620259949359 -30.435142493085 38.2745913287171 -0.795178770994475 0.427213187775309 TM4SF18 other 1 1 1 0.557545364026187 -0.795178770994475 5.37673297990501e-15 438.103973400553 53.850892948071 8.13550062805869 1.45669570752382e-14 -400.494468442348 270.049068635068 -1.48304332418772 0.139216389374176 TOPBP1 essential 7.10965401932839e-11 1 2.11759855002738e-10 8.13550062805869 -1.48304332418772 4.26590772588862e-18 431.71045129822 49.4114876068552 8.73704622562964 2.46451001228579e-16 -639.316383690599 248.689239755114 -2.5707440511706 0.0106783419300993 RYK other 6.0550294261263e-14 1 3.66694444728002e-12 8.73704622562964 -2.5707440511706 0.239905440562822 5.35941201571417 61.1506442064587 0.0876427727828926 0.930225093491547 -251.771742617091 160.64750793095 -1.56723092601791 0.118223328206976 SNRK other 1 1 1 0.0876427727828926 -1.56723092601791 0.280348850466293 34.2290797818114 23.7414392743942 1.4417440908365 0.15052071156485 -59.9555166090745 88.801789538297 -0.67516113043215 0.500144824772721 ZNF513 other 1 1 1 1.4417440908365 -0.67516113043215 6.69398525473256e-13 155.384637599132 20.318750756793 7.64735191936854 3.5197729917913e-13 153.401645516411 75.9996648700179 2.01845160473764 0.0445219927476979 SLC4A1AP other 8.3072357011231e-09 1 5.01180476301163e-09 7.64735191936854 2.01845160473764 0.633831183000095 -6.1165009006187 12.5743440934088 -0.486427033901898 0.62705467899714 -40.0287371324649 48.2277800218826 -0.829993358896107 0.407267737849232 PLB1 other 1 1 1 -0.486427033901898 -0.829993358896107 3.22341625502653e-06 301.367859660114 59.3229304079873 5.08012428899733 7.00103653575507e-07 206.623454373004 227.527831011841 0.908123869744316 0.36461372302814 SPDYA other 0.0274957406553763 1 0.00784256112735283 5.08012428899733 0.908123869744316 1.21671765844737e-05 85.7794855153697 25.9008445778808 3.31184125125499 0.0010522836412249 -152.90947548528 68.0030772510748 -2.24856700117733 0.0253407356542587 KIAA1143 other 0.0989313128083555 1 1 3.31184125125499 -2.24856700117733 3.63818734615716e-10 179.84875213877 28.808900967603 6.24281892395057 1.64408973071451e-09 -46.505321847898 75.6382253145338 -0.614838881458554 0.539175131673581 KIF15 other 4.02747339219598e-06 1 2.107723034776e-05 6.24281892395057 -0.614838881458554 2.53284902694233e-11 371.077844780328 55.0437336893104 6.74150934009754 9.30368588230727e-11 618.010985807642 211.115352039925 2.92736165246177 0.00370646752996092 WDR43 essential 2.95659466914978e-07 1 1.24474013419389e-06 6.74150934009754 2.92736165246177 1.78843330797147e-05 512.514178108651 128.206490812762 3.99756810173634 8.24167059533614e-05 -381.294149664635 337.110448843837 -1.13106594877831 0.25901996173556 ZDHHC3 other 0.143360813966993 1 0.780156538554519 3.99756810173634 -1.13106594877831 0.000456756771413924 919.325025459144 233.955541280647 3.92948600587471 0.000107931739294018 442.281133312268 615.170550497361 0.718956934714587 0.472782384285029 CDCP1 other 1 1 1 3.92948600587471 0.718956934714587 0.312493200443336 -183.976621484005 169.854005778789 -1.08314561461452 0.279699513134405 -614.836318198309 446.619822155772 -1.37664359640506 0.169750413470888 CLEC3B other 1 1 1 -1.08314561461452 -1.37664359640506 0.340286401562973 31.9562170363413 21.9803203507324 1.45385583678613 0.147134906649561 15.9982660212414 57.1300432244289 0.280032450848918 0.779664675128192 SLC6A20 other 1 1 1 1.45385583678613 0.280032450848918 0.00403762193800358 80.6445795101511 29.4234047069851 2.74083099196899 0.00653281446816734 -68.1823928906862 76.4756998941514 -0.891556311155781 0.373415904631195 LZTFL1 other 1 1 1 2.74083099196899 -0.891556311155781 0.891955663323308 19.7999331695685 73.2083272778455 0.270460122581717 0.78701064675259 -53.2158442309082 190.279069414568 -0.279672611363077 0.77994046918911 FYCO1 other 1 1 1 0.270460122581717 -0.279672611363077 0.115466658056692 -86.5223701322158 44.4767023641719 -1.94534139297867 0.0527603253402558 -158.060291886424 115.60140562103 -1.36728693770892 0.172660067345786 CCR1 other 1 1 1 -1.94534139297867 -1.36728693770892 0.920628510432072 -1.86642944873924 4.71825122851148 -0.395576530020438 0.692726398342323 -0.549165522722244 12.2634198377183 -0.0447807813798553 0.964314781316153 LRRC2 other 1 1 1 -0.395576530020438 -0.0447807813798553 9.76950269635444e-09 122.733066278223 21.6723291256308 5.66312303429686 3.77507630167531e-08 -52.3428421137822 56.0609880431573 -0.933676767763837 0.351298741494455 ELP6 essential 9.96658904123058e-05 1 0.000455613958849193 5.66312303429686 -0.933676767763837 4.016532081675e-10 536.454708524131 82.6572781851056 6.49010855792729 4.06634087690734e-10 -349.431213332905 325.886649317976 -1.07224770963832 0.284562705300923 DTX3L other 4.43786629704271e-06 1 5.327719816924e-06 6.49010855792729 -1.07224770963832 4.1236105167497e-21 367.306496864098 35.6876987900327 10.2922438071766 3.65160024692743e-21 -69.1995497753821 135.182257292741 -0.511898167416518 0.609142262029057 ZNF148 other 6.11284023002976e-17 1 5.61871729994724e-17 10.2922438071766 -0.511898167416518 6.84105305177876e-06 66.927601179903 13.4227810159827 4.98612032038751 1.10558429857576e-06 31.6900706370814 69.0865633010413 0.458700927110725 0.646819336909355 NMNAT3 other 0.0567670582236602 1 0.0122171225017949 4.98612032038751 0.458700927110725 1.14520578780378e-10 51.2408217200715 43.8259915119977 1.16918796249125 0.243355269486065 -335.008710978084 62.9698983263967 -5.32014057322449 2.17375242456529e-07 SMIM12 other 1.29900692510583e-06 0.00342713807256964 1 1.16918796249125 -5.32014057322449 3.63518996929031e-11 29.4223017077597 17.7510094899154 1.65750019594519 0.098575512810828 -131.254558920129 25.5049395166536 -5.14624074424584 5.10939821887065e-07 ZMYM6 other 4.21463925039519e-07 0.00802482084255825 1 1.65750019594519 -5.14624074424584 2.41634742374268e-16 224.905016517996 26.6304171432918 8.44541845919413 1.86506767995287e-15 -169.77040117391 102.084481931631 -1.66303827929117 0.0974608052665191 TPRA1 other 3.30435510196812e-12 1 2.74482010458664e-11 8.44541845919413 -1.66303827929117 1.89033353188899e-36 743.44064474788 49.1832096191351 15.1157407274746 1.40125682499869e-37 -98.5536698690832 570.979120159374 -0.172604682709894 0.863094924207244 YEATS2 essential 2.99164184756752e-32 1 2.22421495832043e-33 15.1157407274746 -0.172604682709894 0.470744854574088 -1.46909339523299 21.7127986559247 -0.0676602504593356 0.946106542659913 -33.8748156765735 31.231774782984 -1.08462666345268 0.279061776788535 GRIK3 other 1 1 1 -0.0676602504593356 -1.08462666345268 1.92911266921569e-09 105.058793351801 74.02532723852 1.41922767883602 0.156994660075031 -538.649465927977 112.45453440689 -4.78993104874725 2.76473094692825e-06 MEAF6 other 2.05373334764702e-05 0.0429970956866281 1 1.41922767883602 -4.78993104874725 7.93219537025323e-17 32.0616615876309 15.5600924760952 2.06050585090589 0.0403117466024079 -157.833068100902 23.6135070035894 -6.68401640116017 1.33545628538478e-10 SNIP1 essential 1.09765719533564e-12 2.12871731890335e-06 1 2.06050585090589 -6.68401640116017 0.0107486265376866 105.205392252352 44.3848469933144 2.3702997617227 0.0184791524524139 -28.1344238678371 67.357047969993 -0.417690868524565 0.676506349068287 DNALI1 other 1 1 1 2.3702997617227 -0.417690868524565 2.74315036039364e-30 389.353811720114 29.2333242639646 13.3188346355828 2.10687244528221e-31 140.199691487827 317.855205244828 0.441080369849027 0.659510431169099 POLR2H essential 4.30016250495306e-26 1 3.3288584635459e-27 13.3188346355828 0.441080369849027 0.0125972128666646 17.9125467226696 8.20951362214889 2.18192545223902 0.0299805019354041 -50.2215425224461 31.3262975554566 -1.60317517362336 0.110069476688868 KLF15 other 1 1 1 2.18192545223902 -1.60317517362336 0.111416933280704 -2.47235756370761 3.20573331320973 -0.771229956503203 0.441250070272668 -25.2308962155365 12.2171152972657 -2.065208979503 0.0398648191583273 CFAP100 other 1 1 1 -0.771229956503203 -2.065208979503 0.000462589419447207 9.15599772694555 2.65987922220292 3.44226070511672 0.000669108400120298 60.3806995414519 28.9209823852275 2.08778176125489 0.0377618460608574 CAMK2N2 other 1 1 1 3.44226070511672 2.08778176125489 0.561598112132109 20.9412927730304 19.4947000096412 1.07420441261849 0.28369727797905 32.096855315466 189.215261384682 0.169631429730247 0.865427975668319 LIPH other 1 1 1 1.07420441261849 0.169631429730247 1.69391061747546e-27 286.645180187306 23.0915231525245 12.4134375326371 2.9433128418825e-28 -63.4676261092273 232.702121068464 -0.272741932122545 0.785261633264786 TMEM41A other 2.62759414982793e-23 1 4.62953676899698e-24 12.4134375326371 -0.272741932122545 4.42776012291401e-16 2210.1450830038 267.275473923816 8.2691653317722 6.11438412192678e-15 -2068.42948952081 1020.79759821811 -2.02628757466849 0.043714723267882 RPN1 essential 6.01599767900327e-12 1 8.93739527102037e-11 8.2691653317722 -2.02628757466849 3.27197368139141e-42 420.746332706254 25.4790127644775 16.5134472279418 9.7521402170655e-43 -153.735943699932 245.837689681045 -0.625355468884338 0.532269910898239 SENP2 other 5.19687579815397e-38 1 1.55068781591558e-38 16.5134472279418 -0.625355468884338 0.439447339139025 21.9750733999317 21.1244879313756 1.04026537690851 0.299147248489395 59.8734286930924 57.7295502233203 1.03713658709411 0.300600146427001 HEYL other 1 1 1 1.04026537690851 1.03713658709411 1.37921747830736e-08 117.547567741049 25.841959737474 4.54870949940343 8.13804373409962e-06 -404.061774639707 118.444217237399 -3.41140989458221 0.000744480825241604 IFT122 other 0.000139245796609911 1 0.0841799243855265 4.54870949940343 -3.41140989458221 8.62881083932922e-27 286.287111326909 23.7295697553838 12.0645723575311 4.83250811914408e-27 -279.804741466005 211.648830949777 -1.32202356238103 0.187291777250916 RFC4 essential 1.3340141557603e-22 1 7.58607124543238e-23 12.0645723575311 -1.32202356238103 1.13360682751711e-07 154.566118866516 28.1542841215349 5.48996799916109 9.29716739407688e-08 -362.222926923417 249.105672888376 -1.45409344846887 0.147086140006288 RPL39L other 0.00108191435618233 1 0.00110143542117629 5.48996799916109 -1.45409344846887 2.26330177610276e-06 617.51468213667 122.535760067816 5.03946506550345 8.54325206994352e-07 109.841524984107 289.632459683104 0.3792445263362 0.704803273383339 BAP1 other 0.0195617172508561 1 0.00952060010674505 5.03946506550345 0.3792445263362 6.05201845029676e-06 5692.684302733 1146.05890661142 4.9671829867495 1.20188600078312e-06 2689.45648213035 2752.37739594762 0.977139430838984 0.329368378494669 TKT essential 0.0504193657094223 1 0.0132507931586339 4.9671829867495 0.977139430838984 0.00750907670316406 -28.3875262789066 76.9991927964018 -0.368673037313103 0.712658237039136 -570.393097407148 184.921417683189 -3.0845161396305 0.00224879783242886 PRKCD other 1 1 1 -0.368673037313103 -3.0845161396305 7.64814846848882e-07 133.224176594253 25.7933667553373 5.16505572374285 4.652294325882e-07 2.36961457603348 61.9454019450746 0.0382532762986115 0.969513804169267 RFT1 essential 0.00687262621378405 1 0.00527337561838724 5.16505572374285 0.0382532762986115 1.33425929133692e-10 99.4165381920111 20.4569463385027 4.85979366357803 1.98792476786821e-06 -158.907365101612 49.1294438421906 -3.23446293452945 0.00136923430401015 SFMBT1 other 1.50771299921072e-06 1 0.0215888629790487 4.85979366357803 -3.23446293452945 1.25868956108138e-10 574.666503153467 100.953240389859 5.69240274937418 3.23963194540521e-08 -504.004828311147 242.44950699635 -2.07880327147349 0.0385726485297449 GNL3 essential 1.42496245210023e-06 1 0.000392319428588571 5.69240274937418 -2.07880327147349 0.00571048218321875 201.760668789808 71.0567321043705 2.83943073111574 0.00486305283220652 -101.58132393085 175.54240235165 -0.578671150502774 0.563293478475814 PBRM1 other 1 1 1 2.83943073111574 -0.578671150502774 3.66008215085899e-52 208.511058866589 11.6062190796481 17.9654595037087 4.56432768352556e-48 24.4004126971985 31.4971794561316 0.774685642286883 0.439200813984243 UVSSA other 5.82941284167311e-48 1 7.26686610494104e-44 17.9654595037087 0.774685642286883 8.95099817453172e-07 187.600538091192 57.9349059277765 3.23812622264479 0.00135185812386746 -440.706510195415 141.851247137941 -3.1068215407853 0.00209051307684698 FAM208A other 0.007999507068579 1 1 3.23812622264479 -3.1068215407853 0.509238816719353 -10.3014254696501 68.4315441977617 -0.150536212362529 0.880452747476027 -191.425516850752 167.551836540976 -1.14248533947843 0.25425332395608 ARHGEF3 other 1 1 1 -0.150536212362529 -1.14248533947843 2.49159530650282e-63 786.328687717051 36.4645801909148 21.5641777198621 8.09149705140031e-61 278.862156884811 98.8500203586886 2.82106322156463 0.0051391165477048 SLBP essential 3.9730978757494e-59 1 1.29018920484578e-56 21.5641777198621 2.82106322156463 2.1626287879106e-21 585.948874880664 133.408187207386 4.39215079033937 1.60714491034642e-05 -1008.43496476763 212.781538972368 -4.73929726064526 3.45538443492333e-06 LRPAP1 other 3.21582900762306e-17 0.0536448433521846 0.162257350148575 4.39215079033937 -4.73929726064526 0.349725797816062 1.90377620204206 1.31550595747364 1.44718174115924 0.149019075642372 0.347599049442547 10.1512364935291 0.0342420403331284 0.972709727423723 ZDHHC19 other 1 1 1 1.44718174115924 0.0342420403331284 8.41450688788069e-16 67.9312530935963 7.6674054420844 8.85974448680374 1.15348948626356e-16 108.99195217284 59.1663196142766 1.84212830683726 0.066565223169031 SLC51A other 1.13595842986389e-11 1 1.72158305824836e-12 8.85974448680374 1.84212830683726 1.46867237510386e-23 452.49781606864 40.2189937096116 11.2508487739837 2.80611212489132e-24 -95.1539656600057 310.189916400242 -0.306760344643916 0.759265788596064 UBXN7 other 2.22753539132002e-19 1 4.37472880270557e-20 11.2508487739837 -0.306760344643916 1.49294169465108e-17 429.589215718645 45.3728545006531 9.46797860629337 1.61465512829337e-18 167.830683570945 349.939186594677 0.479599570440041 0.631906238533387 RNF168 essential 2.09832955183209e-13 1 2.44910889859538e-14 9.46797860629337 0.479599570440041 7.82570090397038e-19 336.057799402075 34.048106638627 9.87008772525468 9.23465172804151e-20 86.222796699038 262.281216459294 0.328741790445447 0.742611483412784 PIGX other 1.12463147690958e-14 1 1.41207059573483e-15 9.87008772525468 0.328741790445447 1.77019024318819e-07 424.783814765357 74.0407103768582 5.73716557557672 2.65129207226139e-08 159.345237543638 536.703766943383 0.296896066988938 0.766781096842993 MELTF other 0.00166831306670607 1 0.000322503167669876 5.73716557557672 0.296896066988938 0.00683117237370473 -701.847570447582 416.075974243451 -1.68682551719971 0.0927876218675431 -1978.98615244649 627.407461602372 -3.15422795162851 0.00179038363277564 S100P other 1 1 1 -1.68682551719971 -3.15422795162851 0.00596531711135198 34.6531598910199 27.112116043707 1.27814294668687 0.202292682841211 -58.7512687643571 41.1222211231924 -1.42869881926738 0.154242375858161 ABLIM2 other 1 1 1 1.27814294668687 -1.42869881926738 1.28657492070517e-21 71.2058576271185 8.35658106352166 8.5209318363401 1.10179202930059e-15 -40.2983090811776 16.6708369396403 -2.41729369839588 0.0162943433990624 EXO5 other 1.91725394683484e-17 1 1.6252534224213e-11 8.5209318363401 -2.41729369839588 0.111919570671304 -10.8630380303242 17.2003222583573 -0.631560145627274 0.528206696621284 -66.6938986023896 32.2084569134313 -2.07069524571285 0.0393340881643368 CLDN19 other 1 1 1 -0.631560145627274 -2.07069524571285 2.23208087376821e-27 43.0898128271654 5.96239595571328 7.22692909817167 5.03198647454477e-12 -63.7237327717642 11.1648822827781 -5.70751497040486 3.00288050487989e-08 C1orf50 other 3.46017177051547e-23 0.000476196790463853 6.97232045912923e-08 7.22692909817167 -5.70751497040486 4.14855164449573e-09 95.511043053839 19.8695511128456 4.80690492258235 2.54808870584699e-06 -59.6552694313116 37.2409495447975 -1.60187294256694 0.110352974143292 ERMAP other 4.32113139290675e-05 1 0.0274352710958545 4.80690492258235 -1.60187294256694 7.7906906829476e-30 91.5673062573769 8.44946301787784 10.8370562796279 5.85715883958232e-23 -26.5962619442773 15.8365946035887 -1.67941799421009 0.0942273554041918 ZNF691 other 1.21971053332228e-25 1 9.09031051903176e-19 10.8370562796279 -1.67941799421009 8.19963255600302e-13 244.844734745954 44.9712408348016 5.44447362805425 1.17115284444088e-07 -71.46007943745 65.9858903713993 -1.08295999395082 0.279795945799568 AIMP1 other 1.01413055452645e-08 1 0.00137961805075136 5.44447362805425 -1.08295999395082 0.0295628429018967 57.3058076293046 157.417718503702 0.364036578436099 0.716117729499845 -475.059992636367 248.464792982688 -1.91198111786191 0.0569448303448928 SGMS2 other 1 1 1 0.364036578436099 -1.91198111786191 1.60077584571286e-12 633.247073911822 144.779877776102 4.37386108925385 1.74263335640579e-05 -464.443595567567 213.483010092142 -2.17555296492731 0.0304529718674736 METAP1 essential 1.95870932481426e-08 1 0.175378620988678 4.37386108925385 -2.17555296492731 1.71835203209955e-13 109.374547335746 38.8354136070805 2.81636107812187 0.0052154233632249 -237.973497893727 57.7538935009567 -4.12047540811746 5.03320782798225e-05 DNAJB14 other 2.17423082621556e-09 0.75976272163392 1 2.81636107812187 -4.12047540811746 5.23428087333151e-10 2076.92833936885 379.167128292779 5.4776065338795 9.87203933845785e-08 181.146694257627 563.876521775789 0.32125241477895 0.748267650026421 H2AFZ essential 5.74492770395387e-06 1 0.00116756609255941 5.4776065338795 0.32125241477895 0.338118828455463 12.1855547499884 76.3260024475874 0.159651420999759 0.873274595779682 -117.872506899294 113.320013489432 -1.0401737810443 0.29918628476742 EMCN other 1 1 1 0.159651420999759 -1.0401737810443 1.22356223144554e-07 34.1380367434379 8.95921973905843 3.81038056189318 0.000171741630638517 -13.4875147567629 13.0998094632362 -1.02959625440467 0.304117610596599 SLC9B1 other 0.00116519831300559 1 1 3.81038056189318 -1.02959625440467 7.26475003868942e-07 48.0166777532326 17.90740904184 2.68138610343034 0.00778329848098071 -52.9957438499879 26.2330145534851 -2.02019267522372 0.0443507952583647 SLC9B2 other 0.00653827503482048 1 1 2.68138610343034 -2.02019267522372 1.39315328267225e-10 32.8838730176824 25.6962899946343 1.27971287001155 0.201744654409775 -172.39445518066 37.6431424459466 -4.57970413676832 7.11597838346811e-06 BDH2 other 1.57300937146524e-06 0.109820894392063 1 1.27971287001155 -4.57970413676832 9.17919068340873e-22 232.78629849645 56.1036192707358 4.14922070130819 4.46978232051439e-05 -394.669059966532 78.4791166714206 -5.02896919213487 8.98206445939579e-07 PGRMC2 other 1.37026958521926e-17 0.0140730985949813 0.434105258968358 4.14922070130819 -5.02896919213487 1.37453050647619e-08 166.117829952926 26.7521885368522 6.2095043074361 1.97142658050134e-09 102.466815830767 66.820638704333 1.53346058669329 0.126320441419917 CDC25A other 0.000138800090543965 1 2.52007459785486e-05 6.2095043074361 1.53346058669329 0.00730300298469381 171.181756903512 56.8550678625878 3.01084429829964 0.00284912729987987 2.34053954868046 140.13329985614 0.0167022367351889 0.986686362555783 ZNF589 other 1 1 1 3.01084429829964 0.0167022367351889 0.0484019823837428 219.106988518488 239.358662270994 0.915391932924586 0.360793753324872 -1118.75757757322 589.958300186241 -1.89633331240538 0.0589716767606533 PLXNB1 other 1 1 1 0.915391932924586 -1.89633331240538 3.63169178994226e-07 303.193835896039 55.4200230833781 5.4708356118851 1.01599057914308e-07 81.7019549144979 136.313074620623 0.599369907412662 0.549425149094427 CCDC51 other 0.00335459370636966 1 0.00120090086454712 5.4708356118851 0.599369907412662 7.57127226362116e-14 86.8062774980719 11.6208485532682 7.46987426091692 1.0966427316417e-12 -26.1498692187909 28.5830555070936 -0.914873121675222 0.361068557622578 ATRIP essential 9.688957115756e-10 1 1.54341498051253e-08 7.46987426091692 -0.914873121675222 1.68388819714423e-06 117.86885761577 257.517227428865 0.457712514198023 0.64752306692578 -3082.09641698933 634.714550629479 -4.85587799103181 2.02073334092911e-06 SHISA5 other 0.0147306539486177 0.0314830254516755 1 0.457712514198023 -4.85587799103181 6.15933444150251e-05 25.7662009841371 71.4473401199184 0.360632053494094 0.71865650233564 -355.643719787479 104.185274202725 -3.41356993595337 0.000739602104128641 SPRY1 other 0.4677398574877 1 1 0.360632053494094 -3.41356993595337 0.0071772955434849 35.8074063847411 11.3412051853097 3.15728406281921 0.00177103149318592 35.0472306592186 27.0260509683698 1.29679436704372 0.19579692504126 BSN other 1 1 1 3.15728406281921 1.29679436704372 1.81204831948112e-07 358.037127503663 84.3133274542048 4.2465069083904 2.9801214626557e-05 -457.30630190523 200.918354606769 -2.27608026553997 0.0236158710556713 APEH other 0.00170622469762343 1 0.29437639808113 4.2465069083904 -2.27608026553997 2.08446387703715e-07 48.4875921869747 33.1334037889638 1.46340510307381 0.144506961052948 -169.750047756163 47.5822329430738 -3.5675090733814 0.000425513946861071 INTU other 0.00195606090221166 1 1 1.46340510307381 -3.5675090733814 1.93149214589494e-09 176.378529054392 35.1772475300539 5.01399459703895 9.62626679696244e-07 -200.505289114431 83.6514043524885 -2.39691479977486 0.0172088971142103 RNF123 other 2.05607338930517e-05 1 0.0106890066513471 5.01399459703895 -2.39691479977486 0.000101552541230257 265.35460236448 88.1987970624965 3.00859661585241 0.00286959687425212 -94.5036384297933 127.028525180224 -0.743956038974041 0.457542904050691 HSPA4L other 0.752402777974977 1 1 3.00859661585241 -0.743956038974041 8.32415485750478e-21 80.6980871417128 14.233510615782 5.66958421713864 3.63834704250018e-08 -76.0967945462838 20.4998471847487 -3.71206642959259 0.000249159725097647 MFSD8 other 1.22956091400203e-16 1 0.000439585089674871 5.66958421713864 -3.71206642959259 1.36659290634494e-19 48.5057984078047 12.4332369832263 3.90130088192191 0.000120650717108712 -81.7130123832041 17.2589622679701 -4.73452639356251 3.53718766308578e-06 ABHD18 other 1.9860694707911e-15 0.0549006897187544 1 3.90130088192191 -4.73452639356251 0.00187831929501165 29.785886483937 9.0509603254759 3.29090896576998 0.00113101991059037 -5.03641618064353 21.1509998897599 -0.238117167362942 0.811970161409375 MON1A other 1 1 1 3.29090896576998 -0.238117167362942 0.0098215876167503 -25.6111475580935 86.4296474221003 -0.296323638033779 0.767209894279822 -602.165379425515 202.246772531682 -2.97737942557865 0.0031701671997753 MST1R other 1 1 1 -0.296323638033779 -2.97737942557865 2.31623778631005e-06 289.870531245661 55.8844244131521 5.18696460220571 4.19070638309748e-07 299.325542314802 132.091589359693 2.26604542927954 0.0242375038197341 RAD54L2 other 0.0200053457603599 1 0.00476650944013507 5.18696460220571 2.26604542927954 2.5901077198024e-08 218.420601752065 48.4301278238787 4.5100149755205 9.66185548598599e-06 -272.830605624439 114.472191926945 -2.38337888907164 0.0178436531969793 TEX264 other 0.00025743080627116 1 0.0993335362514219 4.5100149755205 -2.38337888907164 0.0550025620902762 256.410303433259 190.550777398155 1.34562717053361 0.179547523458318 -653.616562063898 450.396605218031 -1.45120223929639 0.147880124268159 DUSP7 other 1 1 1 1.34562717053361 -1.45120223929639 8.80526095886901e-15 147.784089663687 18.7264451899005 7.89173215551824 7.4029275775766e-14 -21.2510101047003 44.2628860217621 -0.480109003607496 0.631537176226633 POC1A other 1.15639492172827e-10 1 1.06394875144931e-09 7.89173215551824 -0.480109003607496 0.0631678866055921 -38.233803619572 39.5871967380394 -0.965812352730526 0.334999167027541 -220.296989047762 93.5705393825586 -2.35434133971472 0.0192693927162046 PPM1M other 1 1 1 -0.965812352730526 -2.35434133971472 1.38305933026993e-07 429.518517977305 109.251664305298 3.9314597238266 0.00010727810590837 -697.047352539327 258.233418878735 -2.69929180958046 0.00738554316647532 WDR82 essential 0.00131252330442617 1 1 3.9314597238266 -2.69929180958046 0.0666652134732417 9.99691613159049 52.5393026966231 0.190275005919198 0.8492371492634 -144.221384741308 81.5270937730232 -1.76899945854601 0.0780270937205789 PITX2 other 1 1 1 0.190275005919198 -1.76899945854601 4.43799520255062e-10 682.330603370049 164.121007751345 4.15748485046978 4.32507506494797e-05 -468.298493535246 241.153044157467 -1.94191408684628 0.0531875069161695 C4orf3 other 4.88933931465002e-06 1 0.420570299315541 4.15748485046978 -1.94191408684628 9.21575126874709e-06 -8.40802733840967 108.812075322111 -0.0772710869958121 0.938465333419178 -643.868481283993 159.911592122867 -4.02640279379672 7.37124485904815e-05 PRSS12 other 0.0757811226829073 1 1 -0.0772710869958121 -4.02640279379672 2.49269958403801e-09 1411.15241590109 281.045947116622 5.02107370833396 9.32646233681229e-07 -133.647217336325 408.928608386244 -0.326822860018862 0.744054149325705 HMGB2 other 2.63553127020339e-05 1 0.0103691608260679 5.02107370833396 -0.326822860018862 3.18630563599201e-09 72.7195916435926 14.0857633869195 5.16263049762162 4.71831254539436e-07 -0.894041797945104 20.4951242989485 -0.0436221700783231 0.965237703298469 SAP30 other 3.34243461215562e-05 1 0.00534396078891365 5.16263049762162 -0.0436221700783231 4.78081597557149e-09 501.669753434841 83.5863497646179 6.00181434944295 6.26253794683212e-09 203.438413751618 122.315687597218 1.66322421717102 0.0974278363274128 MAD2L1 essential 4.96153081944809e-05 1 7.84257627081786e-05 6.00181434944295 1.66322421717102 0.00484049529335938 706.777358490564 379.486536022799 1.86245700808764 0.0636288224935464 -614.151886792453 557.440933759394 -1.10173446117528 0.271561919180934 ANXA5 other 1 1 1 1.86245700808764 -1.10173446117528 0.246771778218233 14.7860594472449 13.1643292299869 1.1231912533427 0.262357695794584 -6.99585433686772 19.6871251202787 -0.355351748623859 0.722604567048834 TMEM155 other 1 1 1 1.1231912533427 -0.355351748623859 1.59324711837591e-05 59.0138655808963 26.7995624745769 2.20204585940084 0.0284983634650665 -84.6646606509116 39.7277406673801 -2.13112196235283 0.0339725334338026 MAP9 other 0.128208595615709 1 1 2.20204585940084 -2.13112196235283 0.00314942887801144 -37.3106091868638 53.0068742293834 -0.703882462968952 0.482105903457914 -245.360138288993 78.5775273372861 -3.12252302411871 0.00198582011664396 GUCY1A3 other 1 1 1 -0.703882462968952 -3.12252302411871 2.65669267276172e-17 76.3949899861192 20.113927390411 3.79811403826283 0.000180009963646994 -135.337198879265 29.768466283186 -4.54632756662062 8.23590463778862e-06 FBXO8 other 3.7161817106591e-13 0.12692352637296 1 3.79811403826283 -4.54632756662062 1.26602462245356e-13 122.966119275313 23.1213347341615 5.318296745803 2.19378505640957e-07 -58.3475636304031 34.2194072841424 -1.70510152750196 0.0893214360813298 CEP44 other 1.60886409021398e-09 1 0.00254149998785048 5.318296745803 -1.70510152750196 0.0663854934136174 -147.474667811918 202.978792587282 -0.726552099025334 0.46812978612748 -663.365797316467 299.492890042567 -2.21496342441446 0.0275974407328664 HPGD other 1 1 1 -0.726552099025334 -2.21496342441446 0.000719763014833159 23.4637094949509 17.0976203122397 1.37233773276354 0.171084790175839 -53.0778058960104 25.1595625991145 -2.10964740292737 0.0357989487379794 TMEM144 other 1 1 1 1.37233773276354 -2.10964740292737 0.0579461493943415 -39.7882633258953 88.1027871234287 -0.45161185729747 0.651907191312714 -281.623696244185 129.645386159473 -2.17226161753082 0.0306965149574806 FAM198B other 1 1 1 -0.45161185729747 -2.17226161753082 0.237847347674665 6.46635658632492 8.43427154792452 0.766676357238717 0.443941312400647 -9.48189943930674 12.2612343517865 -0.773323400178321 0.440005022306758 NPY1R other 1 1 1 0.766676357238717 -0.773323400178321 3.8984557487852e-16 432.010619940196 73.4203325794464 5.88407331814695 1.18212837456552e-08 -193.172495590871 109.005450212018 -1.77213611993847 0.0774996770240692 NAA15 other 5.30579827409665e-12 1 0.000146335671487465 5.88407331814695 -1.77213611993847 3.79593079713267e-05 16.5842095880909 17.731538492213 0.935294452614701 0.350472320823031 -76.969829649238 26.2484354904831 -2.93235875628263 0.00365239194478786 IL15 other 0.294336474009667 1 1 0.935294452614701 -2.93235875628263 3.20770272513103e-09 86.5098143707256 23.4824781950501 3.68401553073564 0.000277162949711162 -68.0605324382471 34.4618046747728 -1.97495555095145 0.0492880154789721 FAM160A1 other 3.3635970775724e-05 1 1 3.68401553073564 -1.97495555095145 4.55649175541967e-23 164.942369580642 36.7711643444191 4.48564445867693 1.07636542451348e-05 -304.345905113983 54.5869004865343 -5.5754384733579 5.98394713632645e-08 ARFIP1 other 6.88394774408803e-19 0.000947079313266388 0.110284401395651 4.48564445867693 -5.5754384733579 6.23279004805493e-29 482.562609960877 37.4485668714157 12.886010073972 5.86292529175374e-30 108.720949244876 216.48691184371 0.502205645223329 0.615930678427438 ICE1 other 9.72128263795127e-25 1 9.24407430750813e-26 12.886010073972 0.502205645223329 0.0551592185053997 -9.08606811145562 117.107441533911 -0.0775874529615141 0.938213688496068 -323.91712444762 171.266744583677 -1.89130192925084 0.0596543514997911 HHIP other 1 1 1 -0.0775874529615141 -1.89130192925084 3.41231523030785e-22 61.7801857585138 11.0093775729636 5.61159660017757 4.96491744558185e-08 -56.266234023974 16.1009431349247 -3.49459243178906 0.000554738556929431 ANAPC10 essential 5.11676668784662e-18 1 0.000596733427784483 5.61159660017757 -3.49459243178906 2.35590567874677e-14 555.192569659441 98.9740842038144 5.60947417827226 5.01974558457027e-08 -162.851493741896 144.747156779354 -1.12507559640802 0.261556142072043 ABCE1 essential 3.0598502955563e-10 1 0.000603122431986117 5.60947417827226 -1.12507559640802 3.44469784408232e-16 222.71640866873 64.0933737412816 3.47487416667664 0.000595252595240817 -383.012637929665 93.7349781215703 -4.08612287115396 5.78831922416118e-05 OTUD4 other 4.69408975213098e-12 0.871547225581948 1 3.47487416667664 -4.08612287115396 2.0248915763188e-12 97.6911279587941 21.7826143802519 4.48482107121911 1.0817436117171e-05 -59.6990132530816 31.3113829298478 -1.906623332059 0.0576347993348387 LSM6 other 2.46753287490208e-08 1 0.110802998148183 4.48482107121911 -1.906623332059 8.69672397850673e-20 137.752297792639 31.7425823795205 4.33966890738899 2.02382004051851e-05 -208.458524561369 46.5479855022518 -4.4783575983387 1.11421223863742e-05 TMEM184C other 1.26754751986736e-15 0.171310131690503 0.202462956853472 4.33966890738899 -4.4783575983387 3.61864708578649e-27 63.6959282824897 9.68563341230168 6.57633069217649 2.5138568857986e-10 -58.243239487096 14.2032150461337 -4.10070813530002 5.46640701170176e-05 PRMT9 other 5.60419874175754e-23 0.82389686480369 3.31628000374552e-06 6.57633069217649 -4.10070813530002 0.0225202021069049 734.903015668128 285.94904984418 2.57004881138298 0.0107113321307707 284.150366269386 523.327634097621 0.542968396383939 0.587604532773703 ITGA2 other 1 1 1 2.57004881138298 0.542968396383939 2.00924196401133e-20 138.374271566795 26.5687319302455 5.20816243432648 3.80536015419689e-07 -226.290080205238 48.6093371519759 -4.65528010591355 5.09468820758134e-06 MOCS2 other 2.95278199031106e-16 0.0788403000123212 0.00434115486390781 5.20816243432648 -4.65528010591355 0.361690573362225 -25.8628508181845 148.346796549859 -0.174340473941357 0.861727108280007 -307.204350275805 232.823379506584 -1.31947380424962 0.188116263881925 EDIL3 other 1 1 1 -0.174340473941357 -1.31947380424962 4.09453961366943e-15 67.7270426144135 15.278717192808 4.43277022277066 1.348953232759e-05 -105.093738857148 24.1182919949357 -4.35742874658021 1.86481063849076e-05 TMEM161B other 5.4338635213007e-11 0.285054954199698 0.137040158915987 4.43277022277066 -4.35742874658021 4.56168261275385e-07 40.042849877087 19.947746875566 2.0073871062669 0.045708598359177 -119.297432357702 35.982839874277 -3.31539791674376 0.00104094332662732 ELOVL7 other 0.00417850127328252 1 1 2.0073871062669 -3.31539791674376 2.46398404692478e-25 113.945538983148 12.6920028111851 8.97774296762139 4.99441748217005e-17 -40.7723101719854 22.8953348895739 -1.78081300704417 0.0760756542899836 NDUFAF2 other 3.78098352000607e-21 1 7.47664297080856e-13 8.97774296762139 -1.78081300704417 0.00952482962844336 3.7347717640086 4.21240110814895 0.886613517593 0.376070237482955 -14.6501790915296 6.83768370891057 -2.14256460450753 0.0330357259153514 ZNF474 other 1 1 1 0.886613517593 -2.14256460450753 4.72789455674525e-22 135.772155971148 12.9396437026967 10.4927275503615 7.72370886235006e-22 -82.4081542537531 85.5789342206724 -0.962949059884958 0.336431531386068 LMBRD2 other 7.08049488818169e-18 1 1.19261788543547e-17 10.4927275503615 -0.962949059884958 0.180751922958173 0.403527947274579 1.93846256549642 0.208169068857535 0.835255662991334 -23.1085210689994 12.9722488096915 -1.78138127074275 0.0759868463694355 RANBP3L other 1 1 1 0.208169068857535 -1.78138127074275 3.17378879767417e-35 643.84430765331 44.2989854401697 14.5340644092829 1.26307914301975e-35 11.5758525865937 296.49483745831 0.0390423411275125 0.968885916954466 NIPBL other 5.0155384369645e-31 1 2.00311721291502e-31 14.5340644092829 0.0390423411275125 7.9536922805391e-06 3.72657406601069 10.8259744917915 0.344225276794828 0.730944815807081 -69.5950390432232 17.1146896583975 -4.06639211299257 6.26958810360521e-05 RNF180 other 0.0657054519295335 0.942632571377043 1 0.344225276794828 -4.06639211299257 0.0178761527762513 88.6017687880851 63.1112041042037 1.40389919738805 0.16149801798926 -147.689855563076 101.37313250318 -1.45689347775106 0.146307754922565 ADGRV1 other 1 1 1 1.40389919738805 -1.45689347775106 3.98816581273849e-14 254.173990026932 46.2106118825581 5.50033811871832 8.71756317210125e-08 -227.041286010151 76.7941727486106 -2.95649107066211 0.00338362522820014 SLC25A46 other 5.14912088082666e-10 1 0.00103390299221121 5.50033811871832 -2.95649107066211 4.52074864390485e-06 266.739488915585 58.8903693609057 4.52942462087289 8.84739663130638e-06 12.1341960613022 97.0956480934416 0.124971574932222 0.900638027934186 STARD4 other 0.038150597805913 1 0.0912255066654001 4.52942462087289 0.124971574932222 1.4345407349338e-10 56.9699125364434 19.4041757503568 2.93596147908502 0.00360834158417646 -134.750688495178 31.7389815155655 -4.2455895577208 2.991579421067e-05 PGGT1B other 1.61859231122581e-06 0.454690156207974 1 2.93596147908502 -4.2455895577208 0.66615803892371 60.4255164749494 129.512129243854 0.466562605585584 0.641187684465957 -91.0691964470824 202.558292834812 -0.449595003850819 0.653361871655762 F2RL2 other 1 1 1 0.466562605585584 -0.449595003850819 5.57495276950761e-06 36.5152186588922 12.330066454229 2.96147784721534 0.00333101014125416 -44.2202018389772 20.1680172510946 -2.19259044101508 0.0291809437564381 CCDC112 other 0.0466344799169312 1 1 2.96147784721534 -2.19259044101508 0.056059818648558 119.73334093928 52.077356282443 2.29914399436683 0.0222632851191583 -179.238019954744 326.944648728389 -0.54822129877907 0.583994616883835 ANKRD33B other 1 1 1 2.29914399436683 -0.54822129877907 7.58831826582341e-05 231.327032252345 53.5463396122768 4.32012783557865 2.19608318006598e-05 -217.217899597395 336.099661902123 -0.646290146107471 0.518642462035512 CMBL other 0.570186234493971 1 0.219191062202386 4.32012783557865 -0.646290146107471 7.80700196994666e-11 17.3113954087364 6.42978306541892 2.69237627966668 0.00753302514331708 -45.4390297590015 10.2835507371592 -4.41861288191143 1.434062959528e-05 C5orf63 other 8.927306752634e-07 0.219884873584428 1 2.69237627966668 -4.41861288191143 0.0016325346219921 141.963891373514 57.3964595268623 2.47339108620581 0.0139948709708168 -100.348229133821 91.7121953167946 -1.09416450873514 0.274850832081833 PRRC1 other 1 1 1 2.47339108620581 -1.09416450873514 0.0104375543905358 238.446585998989 96.2054216808401 2.47851505490025 0.0138021884646484 -52.6200767973981 150.466262047413 -0.349713457896742 0.726825367418508 F2RL1 other 1 1 1 2.47851505490025 -0.349713457896742 2.25488826160294e-09 121.043528192487 27.5608598268528 4.39186327832027 1.61527831401139e-05 -89.4932551946364 43.4705524162396 -2.05870986726186 0.0404813507017836 AGGF1 other 2.39040704612527e-05 1 0.16301388745003 4.39186327832027 -2.05870986726186 6.6021499439401e-18 209.30829127481 38.4817095105235 5.43916301892905 1.19303268394304e-07 -254.67172492551 60.7826922154354 -4.18987240681711 3.77617639265682e-05 WDR41 other 9.34006152569206e-14 0.572204008779288 0.00140479598534293 5.43916301892905 -4.18987240681711 7.53836736506484e-25 256.087983523863 36.4561541027695 7.02454742762921 1.75866431020068e-11 -265.843281382791 66.7362895139488 -3.98348909295033 8.74826826535612e-05 NDUFS4 other 1.15314405583397e-20 1 2.40374237918229e-07 7.02454742762921 -3.98348909295033 0.739409176685555 -120.742210290654 418.521185771314 -0.288497247918602 0.773185061127986 347.692482143032 693.36987822966 0.501453110467929 0.616456392311403 SCGB3A2 other 1 1 1 -0.288497247918602 0.501453110467929 0.0166953059981242 -24.8191107535953 99.5180085836791 -0.249393161165663 0.803244213812691 -437.178889524235 164.872871049897 -2.65161203744628 0.00847922911021519 SPINK1 other 1 1 1 -0.249393161165663 -2.65161203744628 0.611903560610574 7.50229207011818 23.6185014472915 0.317644711154124 0.750999063519826 41.4439556207895 43.2584908619202 0.958053662876899 0.338889620218811 ESM1 other 1 1 1 0.317644711154124 0.958053662876899 2.18425947797978e-09 156.521840261289 29.1737173529208 5.36516613113816 1.7271309908307e-07 -38.5418245607231 48.3325039118908 -0.797430744142371 0.425893934359646 GRPEL2 other 2.31815458397994e-05 1 0.00201348930911043 5.36516613113816 -0.797430744142371 2.79441175154664e-06 40.818426724138 10.5928502648621 3.85339410107004 0.000145382625547254 -20.7051626175549 18.4421321724242 -1.12270980513384 0.26255078471474 ARSK other 0.0239620807695124 1 1 3.85339410107004 -1.12270980513384 0.809027010749049 56.0111419372181 111.804297792737 0.50097485555566 0.616792498419985 118.383493510321 194.696741067856 0.60804044721561 0.543666150275952 RHOBTB3 other 1 1 1 0.50097485555566 0.60804044721561 0.0159912554447835 107.108504118856 41.996354856717 2.5504238280748 0.0113096630407317 20.1367178265538 76.115754519617 0.26455387526066 0.791554248260431 GPX8 other 1 1 1 2.5504238280748 0.26455387526066 4.90288891384967e-13 34.3045119046451 5.88985486599997 5.82433908561531 1.60890281679196e-08 -19.835654796329 9.82887319767448 -2.01810058970159 0.0445587760080338 TIGD6 other 6.10801900887391e-09 1 0.000197830690352739 5.82433908561531 -2.01810058970159 0.124247588056128 149.59819099427 173.620463819814 0.861639162244866 0.389642293727912 -325.016588233645 272.489221730136 -1.1927686026258 0.233995651675666 SERINC5 other 1 1 1 0.861639162244866 -1.1927686026258 0.029711725911508 50.6908062548517 20.1503226755171 2.51563248247343 0.0124648439064806 27.0255706541238 30.5000354193889 0.886083254740867 0.376364099018773 ENPP6 other 1 1 1 2.51563248247343 0.886083254740867 0.368559388879252 2.21290001014667 1.93613545632415 1.14294689605446 0.254080624449309 -1.12444141634772 3.49955558711919 -0.321309774442918 0.748226088011123 CAGE1 other 1 1 1 1.14294689605446 -0.321309774442918 4.26307692342085e-08 122.988071210911 58.3800879494268 2.10667841606291 0.0360681379490291 -273.419927296577 89.9624275048709 -3.03926800198642 0.00260420654446995 CASP3 other 0.000417994692341414 1 1 2.10667841606291 -3.03926800198642 2.0530143359465e-20 69.7534528473619 14.3331909391579 4.86656831290772 1.93344272920998e-06 -89.2226047726469 22.087131007656 -4.03957420915012 6.98508827823644e-05 PRIMPOL other 3.01690456667339e-16 1 0.0210203893519709 4.86656831290772 -4.03957420915012 8.30639861825321e-08 440.130406123885 144.041610746285 3.05557820301753 0.00246862739403211 -720.274051227201 254.258044005611 -2.83284666191841 0.00495745497884227 ERAP1 other 0.000799407803020689 1 1 3.05557820301753 -2.83284666191841 0.00498893798783148 163.065467344057 129.409352392485 1.26007482712298 0.208718423080803 -457.378675853324 228.429608950305 -2.00227403949558 0.046244250025305 ERAP2 other 1 1 1 1.26007482712298 -2.00227403949558 0.0380858488019114 8.71082404988665 22.413536929644 0.388641207196789 0.69784450330909 -72.1216287714612 35.4852410507675 -2.03244015359172 0.0430769441286692 CMYA5 other 1 1 1 0.388641207196789 -2.03244015359172 0.0514761342307139 31.9049746908823 13.0868234094927 2.43794645137028 0.0154261396302176 15.7544068768291 88.1714428502202 0.178679245428609 0.858325579141623 EGFLAM other 1 1 1 2.43794645137028 0.178679245428609 1.07369268914633e-21 248.935824034367 49.8398508849778 4.99471446270716 1.05713136841076e-06 -325.584895634537 76.8470700332264 -4.23678997122159 3.11055330558105e-05 CFAP97 other 1.6017347536685e-17 0.472493047117761 0.0117035013796755 4.99471446270716 -4.23678997122159 5.86655874939969e-22 229.003606681364 21.4636746311223 10.6693569771743 2.63532331010784e-22 -37.7098048496965 141.960909578375 -0.265635131260394 0.7907291244972 RICTOR essential 8.77637188910194e-18 1 4.07579103141279e-18 10.6693569771743 -0.265635131260394 6.75032863689351e-14 102.755460402183 34.909415868066 2.94348839265972 0.00352441364880797 -287.234067936969 54.7887003159668 -5.24257860253096 3.17547476147834e-07 PAPD4 other 8.64987111531534e-10 0.0049981972745669 1 2.94348839265972 -5.24257860253096 0.0709536010663178 13.0006939625261 15.3158761620897 0.848837756647952 0.396715266644427 -36.8438969851183 25.0179568922645 -1.47269807617705 0.141984418454282 EBF1 other 1 1 1 0.848837756647952 -1.47269807617705 1.01309103014414e-06 21.2264383254985 18.9552734217694 1.1198170479103 0.263779570425076 -119.770051081669 29.4582672449383 -4.06575342961657 6.27368870833462e-05 ANKRA2 other 0.00901347089519237 0.943186360411026 1 1.1198170479103 -4.06575342961657 3.83091868919857e-12 120.925399028452 35.8056591563857 3.37727057335533 0.000838622357335852 -254.114407433111 58.4873126286331 -4.34477831194976 1.96817298253079e-05 UBLCP1 other 4.61740629609103e-08 0.300599059621928 1 3.37727057335533 -4.34477831194976 6.10093131185492e-12 117.647190508171 18.7314544366621 6.28072907557602 1.32935408165803e-09 -17.4662107983798 29.1104316146587 -0.599998345252451 0.549006859397595 UTP15 essential 7.28878263827308e-08 1 1.71101163850205e-05 6.28072907557602 -0.599998345252451 2.10273491451843e-10 -2.0327843828968 24.6744549250675 -0.0823841656916053 0.934402268094388 -207.250154056636 38.0227906532364 -5.45068235382127 1.13172543964572e-07 TLR3 other 2.35625283615432e-06 0.00178744715937645 1 -0.0823841656916053 -5.45068235382127 1.38797331600284e-08 4.19265842392988 3.13667037182968 1.33665891755283 0.182459222645352 -18.7066592041068 4.8335398394201 -3.87017792871882 0.000136436471682005 KLKB1 other 0.000140102026517326 1 1 1.33665891755283 -3.87017792871882 1.47595341197199e-19 393.462546970795 58.1762839675877 6.76328084464812 8.22999284979491e-11 -299.520131518229 91.0722776608868 -3.28881784019403 0.00113862067010731 NSA2 essential 2.1445603075953e-15 1 1.10298364172951e-06 6.76328084464812 -3.28881784019403 4.09769457759843e-14 224.37737532138 42.647235680146 5.26124077546804 2.90334586235887e-07 -205.925400899862 66.76227191643 -3.0844576583258 0.00224922485531627 GFM2 other 5.28889439130629e-10 1 0.00333855740712647 5.26124077546804 -3.0844576583258 0.0907135590352419 11.1368997148151 5.07820988200685 2.19307590146588 0.0291678430212056 13.1611520785545 29.5149111076419 0.44591535548101 0.656021127519051 TERT other 1 1 1 2.19307590146588 0.44591535548101 1.27263375576685e-27 143.005034186335 11.4644510711466 12.4737794508318 2.19538516775404e-28 -3.78821726295216 65.9465809303155 -0.0574437250500537 0.954235186535714 CCDC127 other 1.97500032557458e-23 1 3.45377994591066e-24 12.4737794508318 -0.0574437250500537 0.321021278218471 -105.479012728192 78.5955140087265 -1.34204876777676 0.180737614321639 -163.931584924242 140.694209380617 -1.16516227388407 0.245009007604552 FOXQ1 other 1 1 1 -1.34204876777676 -1.16516227388407 0.0710704819548043 1.27747081396699 16.2926835149227 0.0784076369492439 0.9375614482499 -51.8095992360359 26.2616877963192 -1.97282062135007 0.049528499465551 ACSL6 other 1 1 1 0.0784076369492439 -1.97282062135007 0.000902109259934126 -5.14627834760514 5.83904505613772 -0.881356163230085 0.378903215309297 -34.0809468544483 9.34667494533866 -3.64631776046144 0.000318701655390528 CSF2 other 1 1 1 -0.881356163230085 -3.64631776046144 1.05559031772699e-06 157.45665756612 74.4713955162043 2.11432398271439 0.0353941877274991 -389.798260451057 119.320111852292 -3.26682781636674 0.00122665929685762 SEPT8 other 0.00937997556332204 1 1 2.11432398271439 -3.26682781636674 3.16734038233231e-05 -16.5070530676689 21.8360113348905 -0.755955509204797 0.450327658578333 -152.429564541455 34.9862560896972 -4.3568412736321 1.86949332559152e-05 SHROOM1 other 0.247590997686917 0.285752054816663 1 -0.755955509204797 -4.3568412736321 1.42279880720168e-08 59.9723296071299 14.3355434221012 4.18347096034532 3.87339465617639e-05 -44.6208223038984 22.968800741975 -1.94267096506936 0.0530840175117841 GDF9 other 0.000143475031718217 1 0.378004584496254 4.18347096034532 -1.94267096506936 1.87066457632051e-09 579.709425384465 130.049489372986 4.45760631725236 1.21121785832623e-05 -420.836517370387 208.368857744067 -2.01967089480947 0.0443944220556344 UQCRQ essential 1.99300603961187e-05 1 0.123556333727859 4.45760631725236 -2.01967089480947 0.0040565976533375 3.41424047948397 1.99570850878733 1.71079116236198 0.0882556301286608 -5.33268873534719 3.19757889378157 -1.66772702488055 0.0965165327934288 LEAP2 other 1 1 1 1.71079116236198 -1.66772702488055 1.13163428862348e-19 55.8179462173115 5.70517714597862 9.78373585764214 1.42486955670891e-19 5.05979589050107 15.1481494909577 0.33402072599834 0.738620356994909 GJB7 other 1.64664105337603e-15 1 2.17634576091718e-15 9.78373585764214 0.33402072599834 0.000187366708055736 83.0013877645427 21.2123165780647 3.91288652793223 0.00011529917852154 -16.1152262184702 53.3793726732322 -0.301899880261265 0.762959088007664 SLC35A1 other 1 1 1 3.91288652793223 -0.301899880261265 0.721521078092877 -1.72733128729857 14.3177784614576 -0.120642409152259 0.904064337739754 17.2325996719325 25.0165411627504 0.688848212861329 0.491512478793416 GRIK2 other 1 1 1 -0.120642409152259 0.688848212861329 0.1757304438678 -154.474031996526 131.543086456512 -1.17432269652267 0.241308219223821 -419.483766319427 235.735079722177 -1.77947111992752 0.0762957521228479 FABP7 other 1 1 1 -1.17432269652267 -1.77947111992752 0.749681855059275 4.37141910514838 6.9774226938228 0.626509141981387 0.531506483639945 -0.840030154904064 11.3075618641474 -0.0742892380334902 0.940834844570217 TLX3 other 1 1 1 0.626509141981387 -0.0742892380334902 0.0668208755857487 17.5554277028231 10.9445990885941 1.60402656695926 0.109872953820441 -22.694421929962 20.0046685050447 -1.13445628575345 0.257605664562556 TXLNB other 1 1 1 1.60402656695926 -1.13445628575345 0.0027114003453177 400.322892131097 138.594254398953 2.88845229455718 0.00418397212776936 -238.023831410721 253.241778574667 -0.939907438458227 0.348102044694454 CITED2 other 1 1 1 2.88845229455718 -0.939907438458227 0.000219351188016112 36.4756888090731 32.4102169286295 1.12543797190238 0.261395561018646 -156.275994199503 52.5237683070809 -2.97533857978036 0.00318966245221613 CREBRF other 1 1 1 1.12543797190238 -2.97533857978036 0.00292360022511996 21.2253023553636 60.586625831127 0.350329830456723 0.726362319784637 -337.55364565221 109.595870525367 -3.07998507639099 0.00228210527628606 DCBLD1 other 1 1 1 0.350329830456723 -3.07998507639099 4.42105206136121e-07 631.032132919093 124.328799760822 5.07551053443 7.15803182771025e-07 61.2272681230632 205.621478398138 0.297766889918527 0.766107562223674 SFXN1 other 0.00405454684547436 1 0.00801484823748717 5.07551053443 0.297766889918527 0.332016870582083 -5.4484953165769 4.0610833018756 -1.34163594084872 0.180833068690708 -7.96654222214533 7.56735240643175 -1.0527515826241 0.29338917495148 SAMD3 other 1 1 1 -1.34163594084872 -1.0527515826241 0.213693534891596 -19.9382453971018 43.2528803172875 -0.460969194440741 0.645189073514108 -141.608105251097 80.5966693180027 -1.75699698820515 0.0800434342205268 TMEM200A other 1 1 1 -0.460969194440741 -1.75699698820515 0.575845270312166 -5.85496073633424 6.496530362406 -0.901244265741543 0.368261664016734 2.97950444320163 11.8839691983591 0.250716271093419 0.802224163390946 IL22RA2 other 1 1 1 -0.901244265741543 0.250716271093419 0.553928020955957 12.9426674789386 38.1240484012632 0.339488276342387 0.734505843775932 -63.033416437641 71.5977253737083 -0.880382946645785 0.379434839856394 DACT2 other 1 1 1 0.339488276342387 -0.880382946645785 7.9835107243636e-10 104.963042876991 19.7605802173055 5.31173891265949 2.29603369928355e-07 -63.296613975526 34.5365971441812 -1.83274031634557 0.0679588928951662 PDSS2 other 8.67967285952811e-06 1 0.00265651099007107 5.31173891265949 -1.83274031634557 0.020977406355303 20.2080455484231 26.926655085124 0.750484807137718 0.453616284647997 -109.600851130338 48.1171386586938 -2.27779236641152 0.023520809926089 STXBP5 other 1 1 1 0.750484807137718 -2.27779236641152 0.355933588235703 2.02611955306355 9.94077888262026 0.203818994164116 0.838647918468238 -19.415033021486 18.1290111558737 -1.07093723174171 0.285150499525791 IL31RA other 1 1 1 0.203818994164116 -1.07093723174171 0.630064529324528 2.14810147932814 13.0512685454549 0.164589478168099 0.869389359507823 -20.3156475409023 24.4166876799359 -0.832039456260745 0.406116557471689 RAET1E other 1 1 1 0.164589478168099 -0.832039456260745 0.885076200200431 5.54942400178946 11.5204879061497 0.481700432047425 0.630408967136925 6.49124147187106 22.5523334235227 0.287830148214309 0.773697566350261 PI16 other 1 1 1 0.481700432047425 0.287830148214309 1.30176630708339e-10 99.5064068900326 18.1099541675331 5.49456978021646 9.00357186535317e-08 -149.285299958944 47.9743343588094 -3.11177428419141 0.00205769817102063 DAGLB other 1.47203734004989e-06 1 0.00106692326604435 5.49456978021646 -3.11177428419141 8.32957896778083e-06 39.7453932810003 14.3214694673749 2.7752315062042 0.00589735660560411 -108.810080863171 37.4046818256369 -2.90899629544752 0.00392423578548981 KIAA0895 other 0.0686690490103852 1 1 2.7752315062042 -2.90899629544752 1.309034554977e-06 206.057630974584 50.3896147027529 4.08928768735608 5.70883782596173e-05 -290.447811780246 146.841687550908 -1.97796563513036 0.0489454030103948 STK17A other 0.011552229947672 1 0.54896184534448 4.08928768735608 -1.97796563513036 7.08013760081829e-06 161.442319531484 48.598483388669 3.32196209170438 0.00101771103508265 -362.215184138661 137.556839291181 -2.63320374330441 0.00894778136827606 TRA2A other 0.0586660201603804 1 1 3.32196209170438 -2.63320374330441 0.197130933166976 168.071693912181 101.158262150369 1.66147272935894 0.0977748877025327 25.3422778628481 168.476020223687 0.150420682000922 0.880544621817076 GALNT10 other 1 1 1 1.66147272935894 0.150420682000922 2.21908566532628e-05 61.1737359264369 39.3210694425577 1.55574954582054 0.120930400785205 -208.283806468098 65.537823313969 -3.17807024914883 0.00165371657874234 SAP30L other 0.176395119536786 1 1 1.55574954582054 -3.17807024914883 5.12785029188416e-08 4817.66935799872 1003.0292167886 4.80311966726496 2.58373318970864e-06 -1454.90071816423 1673.58702221551 -0.86933078402951 0.385432689986509 RPS14 essential 0.000500016681961625 1 0.0278164715204032 4.80311966726496 -0.86933078402951 0.250119587710248 6.73635058175441 4.09710347072994 1.64417389745694 0.101291316177395 3.55675495087522 6.83716516072756 0.520209014593518 0.603339497290011 MYOZ3 other 1 1 1 1.64417389745694 0.520209014593518 1.4563870874504e-15 242.130289350032 32.641807653593 7.41779658527519 1.52178644434612e-12 -299.982652545357 115.726133547414 -2.59217726670573 0.0100525371768043 COG5 other 1.95432583264969e-11 1 2.13491420277317e-08 7.41779658527519 -2.59217726670573 9.27314456434128e-07 81.5642273174986 18.9950242432931 4.29397858474952 2.46158645120482e-05 -95.2852995617952 54.8375228881147 -1.73759306663443 0.0834399310539146 BMT2 other 0.00827071763693599 1 0.244755540843296 4.29397858474952 -1.73759306663443 0.102635168213158 -5.45030936574683 5.44000704330324 -1.00189380682076 0.317305411369692 -33.2303654144646 15.7049818377556 -2.11591237466936 0.0352815012974763 GPR85 other 1 1 1 -1.00189380682076 -2.11591237466936 2.16814965096387e-18 226.23027989822 36.2881221169676 6.23427906158965 1.7167793790499e-09 -209.588705117332 59.2753992795183 -3.5358463656904 0.000477357058092796 SLU7 other 3.09308229206505e-14 1 2.19902270662502e-05 6.23427906158965 -3.5358463656904 8.32602629476038e-20 71.4188325651508 8.39298357809268 8.50934973250368 1.17657567791767e-15 -55.6343367492484 22.4219463904747 -2.48124474924635 0.0136948338629482 RP9 other 1.21410115430196e-15 1 1.73474317952182e-11 8.50934973250368 -2.48124474924635 2.08634913683946e-09 344.905042794357 71.2288134874772 4.84221238438846 2.15300868795638e-06 -178.998984758526 116.349816782125 -1.53845523533327 0.125095560831109 PTTG1 other 2.21591141823719e-05 1 0.023297707012376 4.84221238438846 -1.53845523533327 3.86893894620962e-12 140.920258747427 29.6493108028942 4.75290166723441 3.24738353111848e-06 -136.749023396479 48.227903344657 -2.83547518993751 0.004918018486132 CAMLG essential 4.66091074849873e-08 1 0.0346690665782209 4.75290166723441 -2.83547518993751 0.335085563382694 -1.46529445532626 21.6800790804122 -0.0675871360935275 0.946163950719182 -81.6167362272149 57.503559146555 -1.41933364540453 0.156946732772795 BMPER other 1 1 1 -0.0675871360935275 -1.41933364540453 0.000154794040349618 43.3116583822864 14.2162885634313 3.04662206236426 0.00254169610031518 -30.3913239945775 23.5667391511056 -1.28958545345259 0.198290079826364 RELL2 other 1 1 1 3.04662206236426 -1.28958545345259 0.35876370338521 3.43160369946702 2.44077654234087 1.40594750889234 0.160876833559844 1.68294166080051 4.05697149412054 0.414827085484694 0.678594285724756 SMAD5-AS1 other 1 1 1 1.40594750889234 0.414827085484694 0.254487429007898 1.52388843391793 24.5250518809716 0.0621359922626822 0.950500168676824 -77.8568743797533 51.2718911676259 -1.51850990097502 0.130047350222377 KCNK5 other 1 1 1 0.0621359922626822 -1.51850990097502 0.193023158978219 2.1822672268367 4.04502890186713 0.539493605553571 0.589986042279777 -11.9629501314178 8.42371860358661 -1.42015073085707 0.156704790655151 KIF6 other 1 1 1 0.539493605553571 -1.42015073085707 3.03961565470719e-12 161.209297178692 24.1487666962395 6.67567413303124 1.37027767209336e-10 -144.335754111345 63.9345354370495 -2.25755537480145 0.0247636065687073 ZNF12 other 3.67611117280287e-08 1 1.8243876926251e-06 6.67567413303124 -2.25755537480145 0.0244776393814483 92.2713039931195 35.748513857654 2.58112279465748 0.0103701303921355 -38.5093935729555 100.587813779107 -0.382843528715348 0.702133695921741 SLC29A4 other 1 1 1 2.58112279465748 -0.382843528715348 0.000859381523187236 117.901627714908 32.4944141357718 3.62836600845544 0.000342138219045074 -54.7743982477532 136.084361847122 -0.402503252425779 0.687638183044544 STEAP1 other 1 1 1 3.62836600845544 -0.402503252425779 7.0238559334533e-13 452.818800339311 61.6268533447761 7.34775143890572 2.39749516098188e-12 -119.103250651043 173.974081677105 -0.684603416226665 0.494181442452674 CDCA7L other 8.70958135748209e-09 1 3.34906099037559e-08 7.34775143890572 -0.684603416226665 0.000253587251900861 52.4942270648578 12.8656774466198 4.08017590077619 5.94129076088064e-05 62.9086860944946 35.3336376510744 1.78041917777412 0.0761401965426243 SP8 other 1 1 0.570185674321715 4.08017590077619 1.78041917777412 4.70816230837116e-11 109.836576645514 18.2076786413284 6.03243163553002 5.25854893130367e-09 -125.175168442343 48.0333083536941 -2.60600763787939 0.00966519433125664 MIOS essential 5.43886909863036e-07 1 6.60841844196932e-05 6.03243163553002 -2.60600763787939 0.0571904533566017 77.1717975440713 36.0842508228842 2.13865594502324 0.0333955479354189 -48.9513723247881 125.566548939777 -0.389844052720329 0.696971022504312 KIAA1324L other 1 1 1 2.13865594502324 -0.389844052720329 7.45532587194545e-11 96.7581540968843 15.4644695760834 6.25680393503608 1.52725434693035e-09 -34.5831492719745 34.9462980416189 -0.989608376566472 0.323248319108484 USP49 other 8.53187492785437e-07 1 1.96007822885041e-05 6.25680393503608 -0.989608376566472 0.421437075177771 2.9046294384179 2.2555793233523 1.28775317646598 0.199003915953704 4.4250495013423 6.78991540602532 0.65170907687827 0.515178109176684 INTS4P1 other 1 1 1 1.28775317646598 0.65170907687827 0.000877126062960034 79.2082075388101 22.5712031982325 3.50925942419466 0.000525406457493919 -12.7631793161862 44.7000443773835 -0.285529455148458 0.775455057181912 SYTL3 other 1 1 1 3.50925942419466 -0.285529455148458 0.113930488363871 -0.776185841097427 2.26417830748372 -0.342811270001096 0.732006201788359 -12.5823468043191 6.16609104503455 -2.0405710380244 0.0422625814390491 IQUB other 1 1 1 -0.342811270001096 -2.0405710380244 0.365053220252174 52.7146303398715 131.262219795481 0.401597888729948 0.688301233703381 581.296168101072 410.372334156749 1.41650915453534 0.157792113943623 HEY1 other 1 1 1 0.401597888729948 1.41650915453534 0.00230675245301264 179.631043532282 53.3576396381338 3.3665477849193 0.000872672970620312 40.30512553662 173.209926970564 0.232695240056706 0.816175674404399 ZNF704 other 1 1 1 3.3665477849193 0.232695240056706 0.196732491650937 340.618364134509 271.216582632555 1.25589062743992 0.210245330497218 -672.858904057085 880.230760696884 -0.764411940710159 0.445291813797756 FABP5 other 1 1 1 1.25589062743992 -0.764411940710159 0.703091212184247 24.2434161497594 40.7945591838264 0.59428062552447 0.552829531838315 -26.6533963880124 102.985202464408 -0.258808020474824 0.795983527106874 SHH og 1 1 1 0.59428062552447 -0.258808020474824 0.253601231797458 -30.3373721532657 22.5024530716278 -1.34818066531229 0.17871779686869 22.1816366442795 44.5638915244233 0.497749094289103 0.619061592720394 TAGAP other 1 1 1 -1.34818066531229 0.497749094289103 5.02194345237177e-05 18384.0684292716 4078.3381904718 4.50773515355402 9.85758684270624e-06 22158.3235127919 18827.8568751634 1.17689037364746 0.240299266701275 COL1A2 other 0.384530210148107 1 0.101286704808807 4.50773515355402 1.17689037364746 0.461447731850663 -112.733530620362 96.4032011668051 -1.16939613265851 0.243264050780228 7.65072983148816 190.91704294326 0.0400735822928177 0.968063753448275 FNDC1 other 1 1 1 -1.16939613265851 0.0400735822928177 0.00156698744146555 80.9778545679193 22.8957764417365 3.53680316428604 0.000476533944234351 35.8443894003738 73.560704706516 0.487276318836009 0.626457902377988 CHMP4C other 1 1 1 3.53680316428604 0.487276318836009 0.0090252194614969 21.3921520632267 9.05724217228528 2.36188363480947 0.0188845410032079 -22.123482183098 24.6779122852829 -0.896489213809698 0.370781376512737 SLC13A4 other 1 1 1 2.36188363480947 -0.896489213809698 0.145004878921665 6.42945510730068 14.8331709720471 0.433451156156488 0.665031861845846 -72.6346598599085 42.9052745745902 -1.69290747070349 0.0916222738553333 PGAM2 other 1 1 1 0.433451156156488 -1.69290747070349 6.60922177754896e-13 362.850384395032 51.8485786931825 6.9982706091564 2.11984405914031e-11 -475.454541500564 225.412114451017 -2.10926791871199 0.0358595312917728 BRI3 other 8.20402699247152e-09 1 2.88913546820233e-07 6.9982706091564 -2.10926791871199 3.2596015773954e-09 193.03552392008 34.9514554289272 5.52296096260174 7.95215773026259e-08 -328.442528218464 151.951734646313 -2.1614924566867 0.0315529153074907 LMTK2 other 3.4170403335836e-05 1 0.000944954903087104 5.52296096260174 -2.1614924566867 3.20809964151795e-06 -2057.83490010419 3774.59188968416 -0.545180766622265 0.586077597832504 -27977.1857355018 6362.10149438183 -4.39747554486636 1.5747844673348e-05 CTSB other 0.0273779223407142 0.241288476085037 1 -0.545180766622265 -4.39747554486636 0.362804796527105 5.69775614041511 6.75989751006151 0.842876113422504 0.40009386335697 -16.9989238259087 21.5053016635789 -0.790452702865259 0.430003727600817 SOX17 other 1 1 1 0.842876113422504 -0.790452702865259 0.510878169814532 -280.91290716251 253.252887609056 -1.10921897007608 0.268326387521434 -170.067236176444 421.952910839921 -0.403047903705452 0.68723313271118 DLC1 other 1 1 1 -1.10921897007608 -0.403047903705452 0.577126202934718 17.951083454368 17.1132520139991 1.04895804956788 0.295128559654292 16.6732183654959 50.736550058483 0.328623415393381 0.742693206173139 ADCY1 other 1 1 1 1.04895804956788 0.328623415393381 0.000133218743384591 6.72755391852315 3.38449656761025 1.98775616524658 0.0478523939710771 -10.2471997869886 5.63902031646489 -1.8171950466411 0.0702998599046777 C8orf48 other 0.972363607964128 1 1 1.98775616524658 -1.8171950466411 0.744262223673193 2.79639943178315 3.65729914233586 0.764607794700966 0.445165530038405 1.70763067300657 10.2105474441179 0.167241833246688 0.867303582500192 C7orf57 other 1 1 1 0.764607794700966 0.167241833246688 0.000252302475120633 22.3641686024799 6.58432061841408 3.39657952559828 0.000785848608598712 -21.3767238624767 21.1524480258784 -1.01060283123371 0.31311810006783 HNF4G other 1 1 1 3.39657952559828 -1.01060283123371 3.12531578386377e-06 243.044537955823 48.4302431036865 5.01844554931259 9.50340263234329e-07 110.445537589288 150.951012256681 0.731664769504712 0.465012491425503 PEX2 other 0.0266901967941966 1 0.0105573299842702 5.01844554931259 0.731664769504712 0.00248797742542331 29.8891415310937 8.5387550901889 3.50040974537806 0.000542983640880688 22.5444421725806 33.3556323227922 0.675881121197508 0.49969248332128 SLC30A8 other 1 1 1 3.50040974537806 0.675881121197508 6.2734133496854e-06 47.9222131759277 9.92909990775936 4.82644082757971 2.32019432907924e-06 -20.3762749621188 40.384342656892 -0.504558787429994 0.61427726127847 MED30 essential 0.0521947990693825 1 0.0250580987540558 4.82644082757971 -0.504558787429994 0.200290662520704 5.58063455015884 14.9868413962577 0.372368960383631 0.709908125443102 110.769188656393 61.678335740212 1.7959172751183 0.0736174119665077 TNFRSF11B other 1 1 1 0.372368960383631 1.7959172751183 0.00921420383019854 125.843544219725 40.8275141271944 3.08232198089924 0.00226892883993822 108.400869086285 135.416684813643 0.800498618286683 0.424133658917129 SBSPON other 1 1 1 3.08232198089924 0.800498618286683 1.72973411305148e-13 188.735729788056 25.140056920024 7.50737082212923 1.19139608747621e-12 -124.355270101491 78.4487599120383 -1.58517827739949 0.11424805081926 PHKG1 other 2.18828662642142e-09 1 1.67629429507903e-08 7.50737082212923 -1.58517827739949 0.0177917689811908 19.1601202813777 11.3635896897542 1.6860975100723 0.0929451499843934 -37.0209176987212 28.6868779372454 -1.29051748955418 0.197987460194624 EN2 other 1 1 1 1.6860975100723 -1.29051748955418 0.000727001510283914 15.4359792459745 4.04190082189955 3.81899010543265 0.000166541240280942 1.95115148431433 16.1583763997076 0.120751704010908 0.903978184883557 CSMD3 other 1 1 1 3.81899010543265 0.120751704010908 1.09762763861784e-08 445.828183625523 77.8298635044716 5.72824059494731 3.31106223061021e-08 -215.93424184297 266.754073574264 -0.80948807622559 0.419109092903785 SPIDR other 0.000111584825741889 1 0.000400671640526141 5.72824059494731 -0.80948807622559 3.70376442649159e-20 155.450097547523 16.2543435485915 9.56360354281999 7.65373597240234e-19 -67.819434939378 62.8248264620753 -1.07950055350042 0.28133159774027 ORC5 essential 5.42342224971163e-16 1 1.16367401724405e-14 9.56360354281999 -1.07950055350042 0.641181536054409 -1340.65095549411 2299.61752631331 -0.582988666660322 0.560383948804333 894.577901817679 3853.22291324571 0.232163547751808 0.816585567869599 DEFA5 other 1 1 1 -0.582988666660322 0.232163547751808 4.25101538174211e-12 278.344313166062 40.95871483026 6.79572868239566 7.00571714397016e-11 -175.208961175347 97.9016708908111 -1.78964219487894 0.0746446658176803 DNAAF5 other 5.10972048885402e-08 1 9.40867812435192e-07 6.79572868239566 -1.78964219487894 0.0206900496070887 66.6586047775688 34.353849663347 1.94035327716674 0.0533816314276614 -169.997680074124 119.641352824258 -1.42089399744447 0.156505711397678 OSGIN2 other 1 1 1 1.94035327716674 -1.42089399744447 0.0367257992006387 34.1282544842214 138.756991638412 0.245957007868523 0.805901008377535 -439.405432581218 232.50023685953 -1.88991391370795 0.0598326772203959 DEFB1 other 1 1 1 0.245957007868523 -1.88991391370795 1.02117379590599e-09 951.381542826614 172.316232717051 5.52113708514516 7.97804860163484e-08 -1002.55086562141 411.879307603316 -2.43408893604089 0.0155853218215883 SUN1 other 1.10215287792134e-05 1 0.00094779217387422 5.52113708514516 -2.43408893604089 0.000255645046745735 122.986215755397 30.6109745426331 4.01771644297404 7.6250482792721e-05 -16.1294747432854 125.215388852308 -0.12881383742944 0.897600856040007 OXR1 other 1 1 0.724455837013642 4.01771644297404 -0.12881383742944 0.468452209337152 11.3822769637727 16.8279383088698 0.676391650293444 0.499373170893469 -34.3168747029285 40.4093745098547 -0.849230534230603 0.396508154253551 GPR146 other 1 1 1 0.676391650293444 -0.849230534230603 0.683300772782037 3.63262311682405 10.7709814844518 0.337260176527814 0.736183778397001 -18.2895268897201 25.8646434670201 -0.707124647321778 0.480101137048729 GPER1 other 1 1 1 0.337260176527814 -0.707124647321778 0.135671836619207 39.8354841967266 90.7177976985082 0.439114321636379 0.660929908111942 -400.018441450311 222.518930182076 -1.79768274601625 0.0733444976473082 TMEM184A other 1 1 1 0.439114321636379 -1.79768274601625 0.596761673202395 33.2027054251379 34.593405519483 0.959798693610497 0.338005812969697 61.6977902745539 87.2342807706953 0.70726542053729 0.480004844584428 NOS3 other 1 1 1 0.959798693610497 0.70726542053729 0.0535274729056529 64.8591002087253 109.755616729891 0.590941057425275 0.555056105034609 -569.931535748483 263.55907298879 -2.16244324008805 0.0314654858067131 MICALL2 other 1 1 1 0.590941057425275 -2.16244324008805 0.288902317520467 14.2067055694699 10.5336147907698 1.34870183233951 0.178567080889226 -11.6360177988932 34.5127305811777 -0.337151468543586 0.736265628645989 CA3 other 1 1 1 1.34870183233951 -0.337151468543586 3.07975451891396e-05 560.106780466638 141.890484332525 3.94745837327617 0.000100898804445141 -506.088687511628 340.725382725912 -1.48532722588131 0.138628107052036 INTS1 essential 0.240990791105017 1 0.946329886890982 3.94745837327617 -1.48532722588131 1.45262556454207e-16 106.306877022173 15.388185067901 6.9083440674186 3.44807231977491e-11 -101.373739796373 38.8129340530628 -2.61185458583936 0.0095036507796344 CDK5 other 1.99619805079371e-12 1 4.6707587643671e-07 6.9083440674186 -2.61185458583936 6.5165953321438e-16 471.593636735985 74.3518756689132 6.34272683094073 9.32840425433055e-10 -580.645020440652 187.573302348663 -3.09556324471669 0.00216868822099479 SLC4A2 other 8.81825680345699e-12 1 1.20681565838274e-05 6.34272683094073 -3.09556324471669 3.48330915339984e-13 391.45215722152 64.1655835925416 6.10065607300143 3.60305913308342e-09 -351.815919692638 161.87554521391 -2.17337287869969 0.0306119446998675 FASTK other 4.36214805280261e-09 1 4.55931102700376e-05 6.10065607300143 -2.17337287869969 6.39542892417665e-12 189.038095051263 31.5354426133969 5.99446462092642 6.44141676350778e-09 -133.033945096472 79.5569319375593 -1.67218546337213 0.0956334107421769 TMUB1 other 7.63678167835933e-08 1 8.06143307952999e-05 5.99446462092642 -1.67218546337213 2.92666327742634e-05 59.0733289980138 15.5659319022175 3.79503966541176 0.000181869469397471 -46.7432143463922 42.9667260305103 -1.08789332268882 0.277601704732349 FMC1 other 0.229508934215774 1 1 3.79503966541176 -1.08789332268882 2.26578192543437e-17 134.904442751689 22.196349838672 6.07777601867895 4.08603258258588e-09 -115.825464761769 35.4999985883424 -3.26268927795969 0.00124402205845457 PHAX other 3.17549336849628e-13 1 5.15861613551468e-05 6.07777601867895 -3.26268927795969 0.00089477776381217 333.424091803351 101.0460592498 3.29972385146737 0.00109644330524201 -1.61618541880196 161.60922794953 -0.0100005763241854 0.992028131613783 ALDH7A1 other 1 1 1 3.29972385146737 -0.0100005763241854 9.69765913994872e-05 373.38332895054 102.043837023346 3.65904830553478 0.000303990763769632 -425.965985903307 282.527930921307 -1.50769513128934 0.132793140322253 FOXK1 other 0.720148167732592 1 1 3.65904830553478 -1.50769513128934 9.84098856202795e-05 364.585374296841 85.9640838219956 4.24113604295234 3.06153038228047e-05 24.4918649935091 336.555961018833 0.0727720433753916 0.942041597618025 COX6C other 0.730299761188094 1 0.301805665085209 4.24113604295234 0.0727720433753916 0.000350827737780205 44.0305728148942 11.6948028370736 3.76496922849466 0.000204725996364212 -21.8810225335003 45.5216560827218 -0.480672814137917 0.631141204535244 OSR2 other 1 1 1 3.76496922849466 -0.480672814137917 5.41080469460104e-09 3838.49511807231 647.251656078522 5.9304523704558 9.1103504613952e-09 -2450.39417336705 2585.45687676504 -0.947760604861843 0.344089513058837 YWHAZ other 5.60288826125937e-05 1 0.000113341870090218 5.9304523704558 -0.947760604861843 0.0145928000830645 95.967206666063 39.9632383135007 2.40138714268415 0.0170019235469835 -183.37379093313 159.900302284292 -1.14680077719368 0.25246806917696 BAALC other 1 1 1 2.40138714268415 -1.14680077719368 0.000528714537890071 387.387822924897 119.267140740426 3.24806833231635 0.00130720627247281 -719.662600331925 477.827609929403 -1.50611347142174 0.13319422040157 FZD6 other 1 1 1 3.24806833231635 -1.50611347142174 0.0241378587643987 224.511653268311 82.3835318834015 2.72520063337494 0.00684149914909402 300.14246790998 330.058437663588 0.909361596796685 0.363961405646779 CTHRC1 other 1 1 1 2.72520063337494 0.909361596796685 7.92727280405315e-16 157.335898582831 18.8232135336796 8.35860987823979 3.27022758218787e-15 -94.6701967141214 75.4126499398861 -1.25536228722351 0.210420733346986 SLC25A32 other 1.07073673764346e-11 1 4.79644279479495e-11 8.35860987823979 -1.25536228722351 4.05098999596677e-18 390.941927738548 41.5239925658629 9.41484437264696 2.06837860088523e-18 -18.2146273235326 167.908732581543 -0.108479333048904 0.913695160791068 DCAF13 other 5.75119049727402e-14 1 3.13524828322183e-14 9.41484437264696 -0.108479333048904 0.477086454239139 -2.27599807460028 3.84110301491809 -0.592537629363427 0.553982900461282 -18.0224061128041 15.4815246020492 -1.16412346820277 0.245394053736543 DCSTAMP other 1 1 1 -0.592537629363427 -1.16412346820277 0.0147141017236994 53.1416446253664 51.8483335103111 1.02494412119915 0.306313784415489 -437.4162897998 186.290710227916 -2.34803060906604 0.0196002749503342 TP53INP1 other 1 1 1 1.02494412119915 -2.34803060906604 6.60726137580711e-14 303.064444925056 38.7245177454455 7.82616447071702 1.15686095770494e-13 -46.7104972432206 139.478812455322 -0.334893138398228 0.73796668812899 INTS8 essential 8.46918763150955e-10 1 1.6584758689658e-09 7.82616447071702 -0.334893138398228 0.00121943510744635 -7.28311363141999 17.801761627947 -0.409123197110236 0.682786064864025 -214.207919053482 59.1360077335945 -3.62229252976427 0.000351063661647691 FREM1 other 1 1 1 -0.409123197110236 -3.62229252976427 0.0127462771020902 109.745236649756 37.3633585010755 2.93724228903558 0.00359822213194557 46.0128074595635 134.689881407755 0.341620372507909 0.732903317426115 GEM other 1 1 1 2.93724228903558 0.341620372507909 0.000123314034879716 235.559201447534 61.7111474208511 3.8171256133206 0.000167607828611474 -187.787947033812 218.477652785595 -0.859529314048879 0.390813884546403 PDP1 other 0.903151991459044 1 1 3.8171256133206 -0.859529314048879 6.55502726647912e-08 47.9387868018686 10.0582779462226 4.76610281185083 3.08358192137832e-06 -72.8582410800738 35.6530883601617 -2.04353239596166 0.0419775505964232 TMEM67 other 0.000635051041576497 1 0.0329912429768267 4.76610281185083 -2.04353239596166 8.81109214624081e-17 241.795044304491 26.8254853948222 9.01363165458926 3.88599776415475e-17 -55.5666693832968 117.735422253319 -0.471962204065822 0.637337805463562 WASHC5 other 1.21778104553194e-12 1 5.82472204869155e-13 9.01363165458926 -0.471962204065822 1.14109381196869e-31 196.259614722065 18.5031305098551 10.6068329690229 4.090234844006e-22 -116.846746038779 49.3006940017371 -2.37008318857868 0.0185059570427887 RPP25L other 1.79334303489e-27 1 6.32186697489568e-18 10.6068329690229 -2.37008318857868 4.96493886615149e-24 259.704449288577 27.6887316928885 9.37942742084064 3.21974912951395e-18 -76.770491527914 74.6419730720278 -1.02851637447783 0.304651965186156 FAM219A other 7.55911942371565e-20 1 4.87180240786756e-14 9.37942742084064 -1.02851637447783 0.758571410722855 3.28398818551402 10.7048469460126 0.306775818661961 0.759256758967143 -12.4123517838499 28.8576200003294 -0.430123890456254 0.667457749886665 C9orf24 other 1 1 1 0.306775818661961 -0.430123890456254 1.97706455267834e-30 272.09758780905 24.1707358532899 11.2573150217938 3.06490535755027e-24 -254.166618699208 79.7451742804355 -3.18723510221941 0.00161064746529973 SNAPC3 essential 3.10003721859964e-26 1 4.77788096188511e-20 11.2573150217938 -3.18723510221941 1.40611315501612e-14 161.75369852904 24.5804412878636 6.58058562231365 2.5235025470979e-10 -87.3937723072667 66.2627908369854 -1.3188966417407 0.188350897036487 NUDT2 other 1.83624316913555e-10 1 3.32849985962213e-06 6.58058562231365 -1.3188966417407 3.1043778647956e-13 255.13837658924 32.1552671530712 7.93457492903681 5.65655311118686e-14 32.1421828615361 139.204379054436 0.230899222279256 0.817567962686773 TMEM65 other 3.89288984245369e-09 1 8.14425919488812e-10 7.93457492903681 0.230899222279256 1.15192440131438e-21 681.34185041723 91.9386156650804 7.4108343429845 1.73157347150438e-12 -1514.49104152749 303.327998527438 -4.99291542119376 1.08652484080122e-06 PSIP1 og 1.71763447479987e-17 0.0170041137585392 2.42680022031339e-08 7.4108343429845 -4.99291542119376 9.94788747298382e-16 27.7242687963774 4.44197340722548 6.24143061083617 1.74456486416368e-09 -57.7328177098536 14.6550793228712 -3.93944082034097 0.000104888914591193 CCDC171 other 1.33988096373619e-11 1 2.23339193910234e-05 6.24143061083617 -3.93944082034097 8.93105118591979e-35 654.724281265671 55.0636500560481 11.8903174889286 2.13997522615805e-26 -185.172379349177 150.660349130056 -1.22907175257724 0.220139277536368 UBAP1 essential 1.41057022430417e-30 1 3.35376917443489e-22 11.8903174889286 -1.22907175257724 0.0422371898677817 45.9509631466673 22.9671677912285 2.00072397103384 0.0464158380832157 -23.0575419559259 44.9319361071628 -0.513166000702342 0.608251744774295 DIRAS2 other 1 1 1 2.00072397103384 -0.513166000702342 4.16444429666999e-08 206.163232086708 89.2813035212631 2.30914227229678 0.0216852371316765 -692.340822196917 174.684101755427 -3.96338771095639 9.44927567886398e-05 SYK other 0.000408490341060359 1 1 2.30914227229678 -3.96338771095639 1.96712836375143e-08 12.4482924942941 2.73075491050748 4.55855355103279 7.78045467375151e-06 -8.74027775833926 5.5510435175731 -1.57452877655704 0.116523385036038 NIPSNAP3B other 0.000196811192793331 1 0.0805743886013706 4.55855355103279 -1.57452877655704 0.000527558181909334 142.850374956134 90.5376079264245 1.57780151505904 0.115769216438166 -456.104451991776 184.043686836456 -2.4782401386964 0.0138080857395258 ABCA1 other 1 1 1 1.57780151505904 -2.4782401386964 0.000232791196000444 191.810669551664 50.9553320360745 3.76429044591191 0.000204653504301113 8.76635689716741 99.6970928437594 0.0879299149766145 0.929997081154493 NFIL3 other 1 1 1 3.76429044591191 0.0879299149766145 0.00308553350012942 23.0675872471004 9.01759273297826 2.5580648771972 0.0112930823785629 -14.577677224736 19.4481422216911 -0.749566568290368 0.45442846982125 LETM2 other 1 1 1 2.5580648771972 -0.749566568290368 1.07347066162059e-28 219.594336675574 20.5867560082605 10.666777057418 2.01759008111848e-22 -139.250146910266 55.4291344181482 -2.51221940180025 0.0125766788902837 METTL2B other 1.67246729080488e-24 1 3.12262416854707e-18 10.666777057418 -2.51221940180025 1.19635806922114e-22 62.4163658320213 9.15960933773617 6.81430435847035 6.31656534942575e-11 -78.5808612759151 17.7200742216007 -4.43456727625472 1.35107401763418e-05 FXN essential 1.80075816579166e-18 0.207335818746141 8.50146530379211e-07 6.81430435847035 -4.43456727625472 0.180864364928664 26.7904059186755 17.1559175571441 1.56158397412672 0.120085850369005 -8.60525806181862 43.242388654759 -0.19900052539932 0.842479697065984 ZMAT4 other 1 1 1 1.56158397412672 -0.19900052539932 0.542416838580955 -5.79635717572749 5.25268563240783 -1.10350353730772 0.270791089370396 -1.6750948396348 22.1570182954021 -0.0756010947548122 0.93979245097846 TMEM71 other 1 1 1 -1.10350353730772 -0.0756010947548122 0.933559896133413 -8.86961634943275 54.5064709805987 -0.162725933083979 0.870857778604934 -38.3281262429927 103.423479335002 -0.370594051654779 0.711234854288024 MAMDC2 other 1 1 1 -0.162725933083979 -0.370594051654779 0.474904868245585 -0.978687991259381 5.74009678803884 -0.170500259385654 0.864745376039186 -21.9139328987434 18.4239816274685 -1.18942437860835 0.235325424591743 CPA6 other 1 1 1 -0.170500259385654 -1.18942437860835 0.0124769400956813 11.6024034555017 4.07715069351614 2.84571366811458 0.00477091290148027 1.9283218029315 13.0289827041732 0.148002483901821 0.882451275342462 C8orf34 other 1 1 1 2.84571366811458 0.148002483901821 0.96823690478466 317.413343050207 1421.63033474591 0.223274177043316 0.82349095313025 3.39675493887202 2705.28513710249 0.00125559960104987 0.998999103910685 ALDH1A1 other 1 1 1 0.223274177043316 0.00125559960104987 2.01658549297527e-07 221.90022929235 44.0843041349498 5.0335427460321 8.78823416529469e-07 -76.154949704516 82.8442774927585 -0.919254196056846 0.35878010843825 KDM1B other 0.00189377543645307 1 0.00978306227280605 5.0335427460321 -0.919254196056846 3.47804503713085e-09 280.462838015642 102.042322939432 2.7484952315532 0.00664156846885046 -992.184399440018 253.554611323065 -3.91309940790559 0.000132141406651928 HGSNAT other 3.63873071784629e-05 1 1 2.7484952315532 -3.91309940790559 0.330474879454133 7.98112328821421 35.0249355256226 0.227869749606693 0.819918698487256 -76.4710874175073 64.3343671167408 -1.1886506519718 0.23561390233408 RASEF other 1 1 1 0.227869749606693 -1.1886506519718 0.00193082187049873 21.04441555557 8.58748038349154 2.45059256217056 0.01489218015202 -17.8067730619232 15.8809052251314 -1.1212693992874 0.263162142733551 GKAP1 other 1 1 1 2.45059256217056 -1.1212693992874 1.22599011978657e-05 19.4604904721153 5.38762159870432 3.61207447768703 0.000361666623710131 -11.2701333315913 9.96337740257018 -1.13115591994779 0.258985810648906 KIF27 other 0.0996729967386485 1 1 3.61207447768703 -1.13115591994779 5.30261492510225e-15 64.3416842504095 16.1072610044632 3.99457637351136 8.34803139147657e-05 -143.371254336053 29.7873036123701 -4.81316658270855 2.46683640620212e-06 C9orf64 other 7.01445503724348e-11 0.0384012423353485 0.789473328691939 3.99457637351136 -4.81316658270855 0.490833679042874 24.4141384585077 72.0528573414897 0.338836506410822 0.734994326243223 -121.029997218777 139.526110380622 -0.867436187310121 0.386467676065868 SVEP1 other 1 1 1 0.338836506410822 -0.867436187310121 0.762278210606299 7.5865367390715 15.1709352586005 0.500070470920415 0.617428299007344 -12.793152390095 41.3110307407648 -0.30967884753045 0.757041433654316 TRPV6 other 1 1 1 0.500070470920415 -0.30967884753045 1.32682541053176e-13 177.09876168342 32.1139841842808 5.51469293461589 8.17189004042171e-08 -191.864845768066 62.4283251148475 -3.07336205824997 0.002333243583382 ANKS6 other 1.68520095391639e-09 1 0.000970003347798057 5.51469293461589 -3.07336205824997 0.0284059789924114 -142.410667298895 139.958111538526 -1.01752349851973 0.309815356601014 -713.40078354859 265.900797014106 -2.68295842494501 0.00774776391263165 FBP1 other 1 1 1 -1.01752349851973 -2.68295842494501 6.32838409736867e-14 235.704432110526 59.6823880400698 3.94931301931615 0.000100075310489661 -547.217030498113 114.736736388439 -4.76932713726073 3.02785650544687e-06 TMEM246 other 8.11868395851427e-10 0.0470559179511497 0.938906563013996 3.94931301931615 -4.76932713726073 1.1724831305378e-07 147.626147725804 25.3814621559847 5.81629800594427 1.70312491560255e-08 82.4270023341842 109.899378165726 0.750022463365404 0.453896649853301 ZHX1 other 0.00111807991328085 1 0.00020916077088515 5.81629800594427 0.750022463365404 1.61340330716767e-05 44.3632551982725 10.4344983093727 4.25159445935447 2.92723460472495e-05 -25.8280336185545 35.3878248071441 -0.72985649045432 0.466110643311224 METTL27 other 0.129798296061639 1 0.289298595984967 4.25159445935447 -0.72985649045432 0.184378726718509 -19.5652265289579 10.930798729291 -1.78991737141124 0.0745960651862226 -35.4730387005735 37.137640387295 -0.955177505372934 0.340348714791923 NCF1C other 1 1 1 -1.78991737141124 -0.955177505372934 0.00496326104896435 11.578761986551 4.55977563737558 2.53932713084436 0.0116638962667174 -6.27853103170092 8.83473105281132 -0.710664647760048 0.477900976549892 C9orf84 other 1 1 1 2.53932713084436 -0.710664647760048 1.55129304630255e-13 64.9406661141613 13.6634516961477 4.7528741315396 3.26434154846415e-06 -96.3803369788816 25.8239556721666 -3.73220656828967 0.000231435102627522 KIAA1958 other 1.9653331603607e-09 1 0.0348305243221125 4.7528741315396 -3.73220656828967 0.153086436915866 5.06454101116163 13.5256721611391 0.374439136985197 0.70836937663133 47.8311046798533 25.5683339905605 1.87071651588687 0.0624581039142969 RNF183 other 1 1 1 0.374439136985197 1.87071651588687 6.75659365825144e-15 254.707079232199 64.5332165145884 3.94691436424247 0.000100766447483885 -645.449599105833 122.835133222985 -5.25460087981617 2.99277675634902e-07 STRBP other 8.90451478220958e-11 0.00471242628054717 0.94518927739884 3.94691436424247 -5.25460087981617 0.65651823241815 -2.76479045405352 95.2129918146085 -0.0290379537640926 0.976855772389696 -283.532735022707 322.907778965559 -0.878061023896697 0.380691283722694 CLDN3 other 1 1 1 -0.0290379537640926 -0.878061023896697 4.57442917683372e-20 215.161215347777 37.7734203204006 5.69610094936447 3.16723123939927e-08 -393.877443064569 72.6507446188486 -5.42151969853838 1.30078369208491e-07 GAPVD1 other 6.6933047715431e-16 0.00205393744980208 0.000383710064653222 5.69610094936447 -5.42151969853838 1.04477973888575e-10 95.2586667226119 21.9006469251865 4.34958232275145 1.9402423381955e-05 -140.218903481264 43.846201075201 -3.19797154697104 0.00155012249416042 CARD19 other 1.18718321729587e-06 1 0.194548099250863 4.34958232275145 -3.19797154697104 0.000146137438050822 443.682638287723 160.852949056001 2.75831211607601 0.00620997847459125 -571.471486714484 322.03572670438 -1.77455927813587 0.0771058565803451 WNK2 other 1 1 1 2.75831211607601 -1.77455927813587 6.01145858457469e-23 130.000400360556 17.4338847111278 7.45676609170065 1.20120933181788e-12 -148.677629622516 33.6616449855993 -4.4168260251726 1.44890579877628e-05 ZNF367 other 9.07189214998167e-19 0.222146237068379 1.68974116706821e-08 7.45676609170065 -4.4168260251726 6.75341772207711e-24 333.349176827169 35.0971945260515 9.4978866923319 1.53389449950279e-18 -81.3692246664433 95.497919456484 -0.852052328778966 0.394975263435127 NDUFB6 essential 1.02712730135071e-19 1 2.32737812409559e-14 9.4978866923319 -0.852052328778966 2.3123811016701e-25 934.318534436495 100.677141380162 9.28034429293602 6.49870793021013e-18 -407.817918632047 287.178407474625 -1.42008559145618 0.156767078654122 NOL6 essential 3.54904251484327e-21 1 9.80849987906616e-14 9.28034429293602 -1.42008559145618 0.346555886492879 762.275799886514 936.39539971271 0.814053336998862 0.416359320647105 -1628.40327888023 2684.62787910659 -0.60656573358023 0.544668401628594 AQP3 other 1 1 1 0.814053336998862 -0.60656573358023 1.59015445272828e-26 75.2581685382707 7.71101132331816 9.75983115349466 2.19846088123884e-19 -38.3974935524473 18.7212850713143 -2.05100736440801 0.0412646089380686 TRMT10B other 2.45440339778609e-22 1 3.35375207432985e-15 9.75983115349466 -2.05100736440801 9.86900576192276e-43 3637.94910532091 287.155048044837 12.6689366253205 4.68683420883172e-29 -2682.68476654381 765.51775657503 -3.50440566989105 0.000537414128571742 VCP essential 1.56788894539667e-38 1 7.38129519548908e-25 12.6689366253205 -3.50440566989105 1.31483640442152e-34 429.806127615929 39.3170730507293 10.9317936017609 3.4234197694337e-23 -318.339784926458 104.814168379834 -3.03718275732373 0.00262713022033656 PIGO other 2.0758637153007e-30 1 5.32067900565385e-19 10.9317936017609 -3.03718275732373 6.60941839574546e-30 1173.51552299074 108.52991204972 10.8128303140347 8.42669139900911e-23 -386.310139552193 289.326534077209 -1.33520467033661 0.182959518248226 STOML2 other 1.03496882658978e-25 1 1.30605289993242e-18 10.8128303140347 -1.33520467033661 0.0339388818645054 13.0994732161181 17.3373214125214 0.755564997869705 0.45065093895867 -52.0327244532624 28.4064362849726 -1.83172306202973 0.0682320899178923 SLITRK5 other 1 1 1 0.755564997869705 -1.83172306202973 2.02578833685013e-33 414.12686331969 34.6200591681318 11.9620495536559 1.17312328339956e-26 -57.1414476195508 97.7667434941629 -0.584467126318494 0.559403313925343 MELK other 3.19426304954529e-29 1 1.83980924535554e-22 11.9620495536559 -0.584467126318494 0.0388489649959919 18.0101734942823 14.0754110167903 1.2795486734134 0.201798294284355 -26.6476854903049 23.5486987144466 -1.13159906682899 0.258803374926599 ARMC3 other 1 1 1 1.2795486734134 -1.13159906682899 7.4536625309432e-05 59.2696046418893 47.073016931189 1.25909934195484 0.20907790088204 -223.607494909449 78.4947734511909 -2.84869278651388 0.00472651230808861 OTUD1 other 0.56044088570162 1 1 1.25909934195484 -2.84869278651388 2.58022221656749e-19 182.340151471231 32.6954902434258 5.57692055123397 5.88480930835879e-08 -238.324888399328 56.3333268356797 -4.23061980867036 3.18461046766747e-05 ARHGAP12 other 3.73409759181647e-15 0.483551253410629 0.000704352826117464 5.57692055123397 -4.23061980867036 0.0160049571065858 45.1630243544274 15.9591759611933 2.82990954321495 0.00500709287698575 28.0676327163913 29.3039404854815 0.957810869507371 0.339018174567348 FAT3 other 1 1 1 2.82990954321495 0.957810869507371 0.660855822154753 -1.54217013049784 12.7987238161378 -0.12049405492705 0.904182073213833 -18.8161983014569 22.7832784553823 -0.825877554817481 0.409608144316335 DEUP1 other 1 1 1 -0.12049405492705 -0.825877554817481 1.96974345959791e-08 27.2501631596168 13.4158337783921 2.03119415533506 0.0432075894543312 -64.0052416728113 19.2019289926814 -3.33327144878028 0.000977431658493755 HECTD2 other 0.000197041408884829 1 1 2.03119415533506 -3.33327144878028 1.842363084641e-05 57.6778333830408 25.2666791874056 2.28276272300124 0.0232551763376131 -108.731453191771 47.1729552517572 -2.30495317945384 0.0219603062513094 FBXO33 other 0.147573283079744 1 1 2.28276272300124 -2.30495317945384 0.580814988661893 -6.27386313116576 17.8842561078708 -0.350803695346583 0.726025258750135 -32.5732910942433 32.1735853377528 -1.01242341356409 0.312295317176283 LRFN5 other 1 1 1 -0.350803695346583 -1.01242341356409 4.83788634440241e-08 784.995509717691 159.958812351899 4.90748523432865 1.61328203235866e-06 -81.8809562231241 297.985978199372 -0.27478123876131 0.783698414461297 SPTSSA essential 0.00047246798039434 1 0.0176347858957125 4.90748523432865 -0.27478123876131 1.35847942313688e-21 173.577329023884 21.9873678781486 7.89441146324695 7.35072449660672e-14 -33.4531744207579 38.2525212641925 -0.874535149976448 0.382604119238102 WRN ts 2.02372679664701e-17 1 1.05651963189728e-09 7.89441146324695 -0.874535149976448 1.87323322442329e-10 87.4877655488837 40.9798988583434 2.1348946187326 0.0336700055505968 -261.029977273589 64.3961905792562 -4.05350029133049 6.60436511101179e-05 MARCH8 other 2.10289161773759e-06 0.992107726976192 1 2.1348946187326 -4.05350029133049 0.0322663852905203 62.9045649803985 44.8151514251651 1.40364503923277 0.16159531203409 -94.592412047202 83.4857832415151 -1.13303616944644 0.258223125984177 CFL2 other 1 1 1 1.40364503923277 -1.13303616944644 5.34989521728909e-24 247.53596182252 32.6921837321469 7.571716953833 5.85864250641044e-13 -207.239824728543 53.0864884531019 -3.90381490219727 0.000119668529223963 SUGT1 essential 8.14414548927918e-20 1 8.2946660605759e-09 7.571716953833 -3.90381490219727 2.46826150872252e-10 205.655552282989 45.2777753862886 4.54208605719767 8.36740358987638e-06 -217.835912058663 86.0267446608611 -2.53218825049613 0.0118962800665185 GTF2A1 essential 2.75581397448869e-06 1 0.0864603812941926 4.54208605719767 -2.53218825049613 0.0823687127081237 -98.6603461525614 56.9442973964751 -1.73257640647733 0.0843128817423542 -189.75724993596 86.7113458772268 -2.18837855664971 0.0294989739702941 ZCCHC24 other 1 1 1 -1.73257640647733 -2.18837855664971 0.00169827661059688 126.412689904209 65.020092378047 1.94420963245033 0.0529048967853789 -349.736182090817 172.036175711737 -2.03292232371425 0.0430350082483649 PGM2L1 other 1 1 1 1.94420963245033 -2.03292232371425 0.248650334378062 4.47630046988898 13.6215942948308 0.328617955652054 0.742700147368301 -22.152201809996 20.258454926203 -1.09347933446512 0.275161633319543 PHYHIPL other 1 1 1 0.328617955652054 -1.09347933446512 0.313340284664224 94.2292144455798 61.746359718222 1.52606914602889 0.128167518008346 81.2192902471148 92.6013396283313 0.877085478170186 0.381222835037704 SLC16A9 other 1 1 1 1.52606914602889 0.877085478170186 0.263184799837442 -18.4554326168625 27.7168463174335 -0.665856151363594 0.506082231843294 -116.57562689 71.2691077441387 -1.63571048635146 0.103087341061713 FOLR2 other 1 1 1 -0.665856151363594 -1.63571048635146 2.36481432163499e-08 559.079223529397 108.069475545684 5.17333151388396 4.5427275735242e-07 -339.751925931377 277.882086883507 -1.22264781347279 0.222549010633339 INPPL1 other 0.000235559154578062 1 0.00515281588664851 5.17333151388396 -1.22264781347279 0.00034996055342452 -951.630588667971 1620.994960954 -0.587065729129663 0.557676942973329 -8788.86665811913 2441.65900469112 -3.59954712809333 0.00038267307105166 GJB2 other 1 1 1 -0.587065729129663 -3.59954712809333 0.0122915681832967 69.159197282583 48.3995097630426 1.42892350813421 0.154231142104345 -95.0692059061683 73.0058873514086 -1.30221286741656 0.194000468071987 CRYL1 other 1 1 1 1.42892350813421 -1.30221286741656 1.40727253989292e-08 178.102919535634 86.6190941418601 2.05616234272719 0.0407280773682711 -450.4762958051 130.647999992348 -3.44801524578626 0.00065490599938576 REEP3 other 0.000141965653824398 1 1 2.05616234272719 -3.44801524578626 5.28499722163994e-09 95.2215930587433 23.7230798122705 4.01387989300996 7.8099234710776e-05 -64.1538704063362 36.0372923842906 -1.78020783920776 0.0762052409457888 SKA3 essential 5.47525712161898e-05 1 0.741161737405264 4.01387989300996 -1.78020783920776 8.29127570181353e-19 187.34336772013 33.0968548965698 5.66045832166204 3.96954741127859e-08 -170.886712739931 50.2768209838928 -3.39891642700874 0.000782326080662879 MICU2 other 1.19021262699533e-14 1 0.000478687722326085 5.66045832166204 -3.39891642700874 1.41642119511244e-10 161.61606113756 26.5830453313484 6.07966691261561 4.07719512975591e-09 -29.5816086193934 57.5873668219121 -0.513682257965953 0.607892717769815 DDIAS other 1.59843131868439e-06 1 5.14786657082981e-05 6.07966691261561 -0.513682257965953 1.88565135362116e-05 171.978064235352 43.0208405938644 3.99755239231377 8.26453380564193e-05 -53.543428764426 93.234037447381 -0.574290572739002 0.566249324330183 PCF11 essential 0.150889821316765 1 0.78199018868984 3.99755239231377 -0.574290572739002 0.102856687197785 36.0332666523497 17.0006918275182 2.11951766539432 0.0349526067331067 23.8011179069723 30.6555394635428 0.77640512362465 0.438184432684623 PKNOX2 other 1 1 1 2.11951766539432 0.77640512362465 8.72632331691732e-13 98.1421381356144 16.5168718683455 5.94193252317367 8.83172641114785e-09 -36.6054828174352 30.1411861091394 -1.21446723048287 0.225650453104364 LRR1 essential 1.0779627193388e-08 1 0.000109937330365968 5.94193252317367 -1.21446723048287 8.5281044132142e-15 626.487396695603 114.239218802839 5.48399580512569 9.69725056280863e-08 -557.759375915124 208.472014697779 -2.67546402678415 0.00792717451251007 RPL36AL essential 1.12042235780808e-10 1 0.00114728171408589 5.48399580512569 -2.67546402678415 1.30753757744329e-22 147.54378072307 17.2929925835313 8.5319981495615 1.12454859964496e-15 -46.2070100571595 31.5575074989303 -1.46421608419885 0.144320161840778 DNAAF2 other 1.96719028526343e-18 1 1.65859672961635e-11 8.5319981495615 -1.46421608419885 0.202238061735322 -192.454375185153 347.126029167595 -0.554422195439094 0.579750578001307 -927.369235705145 545.318768558375 -1.70060025287003 0.0901737789636392 C10orf10 other 1 1 1 -0.554422195439094 -1.70060025287003 2.28412702110658e-10 209.482868757259 49.6512605408377 4.21908460078192 3.35617576054611e-05 -148.335731365718 78.1079267503981 -1.89911238893512 0.0586195021424068 ZNF22 other 2.5545676604056e-06 1 0.329475774412812 4.21908460078192 -1.89911238893512 2.08845184975484e-23 327.712308005267 42.1474132740014 7.7753836486904 1.67231457983204e-13 -219.199757978404 76.9136576003323 -2.84994583299412 0.00471622392793996 KLHDC2 other 3.16358686200863e-19 1 2.39174431207578e-09 7.7753836486904 -2.84994583299412 0.098656744766066 34.4664536396119 17.4862753706489 1.97105746701579 0.049742281799059 2.87641822643246 34.7517620758645 0.0827704281628402 0.934095640233229 EML5 other 1 1 1 1.97105746701579 0.0827704281628402 1.64472802099447e-20 282.456515470233 39.6569448348115 7.12249813107861 9.9895398792574e-12 -194.217779943652 72.3688701052848 -2.68371994285798 0.00773920689828642 NEMF other 2.41890150047657e-16 1 1.37466058278461e-07 7.12249813107861 -2.68371994285798 4.25303699262745e-20 148.21881247669 18.7463720146083 7.9065331873916 6.65255979719346e-14 -61.2365856772765 33.6977711115209 -1.81722955724927 0.0702822854532499 RPUSD4 essential 6.22474494240954e-16 1 9.56770463255413e-10 7.9065331873916 -1.81722955724927 2.30079999337545e-22 1066.57247924302 141.175952277099 7.55491613153458 6.63633542955628e-13 -823.262147024876 261.880097332214 -3.14366061190403 0.00185605122277075 ARF6 other 3.45534143005124e-18 1 9.38377829739258e-09 7.55491613153458 -3.14366061190403 1.01689846541626e-09 96.3430069292885 18.1179770068378 5.31753665946968 2.20774780063783e-07 -45.2666984301197 36.184565025312 -1.25099468235847 0.212019330460655 TTC8 other 1.09794527310994e-05 1 0.00255701350269873 5.31753665946968 -1.25099468235847 0.0140672665784237 18.8526684579316 35.2511823189612 0.534809535956783 0.59321688065911 -154.874476306971 66.4262738378691 -2.33152437068776 0.0204535931895322 TMEM63C other 1 1 1 0.534809535956783 -2.33152437068776 0.821124482759835 6.33126547600231 11.2955074346337 0.560511824071727 0.575590073698479 0.0760692042156453 21.2849164377412 0.00357385496147703 0.997151092474811 NGB other 1 1 1 0.560511824071727 0.00357385496147703 0.121949814123396 7.05648896222486 11.7506121286785 0.600520967329252 0.548660965256715 -25.0585628792189 18.4516711153809 -1.35806468273384 0.175572734760156 CDX2 other 1 1 1 0.600520967329252 -1.35806468273384 0.0209544458548842 37.9835518106083 14.1264931796503 2.68881677338895 0.00761168183468322 48.5651367315166 23.046019993081 2.10731122970895 0.036002628473822 AMER2 other 1 1 1 2.68881677338895 2.10731122970895 2.46425424154423e-05 40.7509147725755 9.57894916204137 4.2542155807716 2.90876585534131e-05 13.8489361443824 16.4499828134804 0.841881496255032 0.400610541099483 AKR1E2 other 0.194813795942635 1 0.287560592459042 4.2542155807716 0.841881496255032 1.65578699494507e-09 111.514796513996 22.1347084795909 5.03800610777489 8.56716084355312e-07 -41.4828550484616 35.0057074953473 -1.18503118538528 0.237035664132471 KBTBD6 other 1.76755261710386e-05 1 0.00954638732797124 5.03800610777489 -1.18503118538528 0.000534438223282924 104.645209786342 27.4210285499667 3.81623940895059 0.000167920418388906 142.264305068165 50.884404161623 2.79583317152135 0.00554691280562604 OTX2 other 1 1 1 3.81623940895059 2.79583317152135 4.47943465745271e-28 414.985172236919 53.2878445050062 7.78761415650679 1.46958202924556e-13 -334.629134303146 90.335380364779 -3.70429761796426 0.000257067647034819 NUDT5 other 6.96417706194174e-24 1 2.10253100924162e-09 7.78761415650679 -3.70429761796426 0.370679401335017 -33.9271999528081 36.5154573173372 -0.929118856651968 0.353651294204588 -93.765868951985 67.7002526756253 -1.38501505158701 0.167182750806381 DACT1 other 1 1 1 -0.929118856651968 -1.38501505158701 0.291285331878058 10.1619480543976 8.07357196226085 1.25866817090362 0.209257923981551 -3.61094768916317 14.4006420933082 -0.250749075337491 0.802202422169089 OXGR1 other 1 1 1 1.25866817090362 -0.250749075337491 0.00335910162625505 45.7406599145465 26.7007200081254 1.71308713400339 0.0878318106543619 -66.023929081886 44.9443895891463 -1.46901381207834 0.142980399172179 BEND7 other 1 1 1 1.71308713400339 -1.46901381207834 4.68120680128193e-13 1067.52102127127 184.033351851741 5.80069324679408 1.83075470164319e-08 -329.659826246384 312.610070007197 -1.05454000966378 0.292571561478705 ATP5C1 essential 5.83559239847805e-09 1 0.000224358988686373 5.80069324679408 -1.05454000966378 1.15036972833313e-23 69.384990275582 14.5522350880925 4.76799542170378 3.03074262968406e-06 -142.613491350386 24.4952691535299 -5.82208305026257 1.62834308358804e-08 PRPF18 other 1.74626124760969e-19 0.00025846689765793 0.0324471305933976 4.76799542170378 -5.82208305026257 5.12739929083609e-16 39.8573095272816 12.2644688436316 3.24981946103419 0.00130003531289579 -102.424799569688 20.8331610832013 -4.91643102842794 1.52616052035143e-06 TAF3 other 6.95582987794824e-12 0.023815734920084 1 3.24981946103419 -4.91643102842794 0.151021778640402 6.31394599114996 48.5613987459526 0.130019854332886 0.896647173902248 -112.716844011435 75.8261826879944 -1.48651613487173 0.138305120534514 VSTM4 other 1 1 1 0.130019854332886 -1.48651613487173 3.13398219852589e-08 466.475928528139 97.9780041338821 4.76102705552894 3.15594469291652e-06 -20.0824037507414 151.021646354452 -0.13297698863385 0.894311369589227 VDAC2 other 0.000309982179256196 1 0.0337275809331988 4.76102705552894 -0.13297698863385 0.999903844463018 0.20814826342159 36.8151410344337 0.00565387657287272 0.995493012454925 0.953534929359753 68.8004285196928 0.013859432998834 0.988952249291969 SOHLH1 other 1 1 1 0.00565387657287272 0.013859432998834 0.00114726475255916 77.8842500405129 31.0466328347289 2.50862148095465 0.0127112596835136 -32.7076770757718 47.8547572581297 -0.683478068843726 0.494895277914608 COMTD1 other 1 1 1 2.50862148095465 -0.683478068843726 0.00187240201303685 30.5078017146371 20.8877186724705 1.46056169144243 0.145289878983802 -55.1010487360642 29.1548171242424 -1.88994664247945 0.0598282810790907 SLC18A2 other 1 1 1 1.46056169144243 -1.88994664247945 4.29729054694386e-08 190.951142124619 75.2018923775195 2.53918001379578 0.0116686862057924 -323.654993677421 104.965863148722 -3.08343097430493 0.00225673374710959 PDZD8 other 0.000421177446505968 1 1 2.53918001379578 -3.08343097430493 0.00773077498522984 67.5500632154299 50.9518586388517 1.32576249463688 0.186043103300632 -115.359061445838 78.5734595647659 -1.46816828589239 0.143226836874021 ZNF503 other 1 1 1 1.32576249463688 -1.46816828589239 3.24853987795428e-17 292.244549061459 40.0389225358246 7.29901132579117 3.19554053348148e-12 -199.426419857773 75.4131952457802 -2.64444994284912 0.00865786239335719 QSOX2 other 4.53691079355094e-13 1 4.45234662529975e-08 7.29901132579117 -2.64444994284912 2.52100546402653e-07 240.970659086246 55.4314865035747 4.34718017296372 1.95289550059066e-05 -45.4099405093335 77.2893161819783 -0.587531922295903 0.557335731261108 FAM204A other 0.00235209809793675 1 0.195777773934214 4.34718017296372 -0.587531922295903 1.93950013143358e-08 550.453900013276 93.209790631231 5.90553735058857 1.04573379062844e-08 170.406077013212 156.065366914383 1.09188912557837 0.275848036925544 NSD1 other 0.000194124568155187 1 0.000129733734065365 5.90553735058857 1.09188912557837 4.34959988762482e-09 958.838971078233 175.331728881839 5.46871337659838 1.03283088471046e-07 49.2783153405258 243.439864388435 0.202425003252124 0.839736928954216 PRDX3 other 4.5248887630961e-05 1 0.00122008312410847 5.46871337659838 0.202425003252124 1.20574666252308e-16 1735.15525606664 249.951593059216 6.94196518145641 2.89306226574751e-11 -144.110943570469 369.355309199624 -0.390168869868828 0.696720448680211 GHITM other 1.65995143029553e-12 1 3.92704271952568e-07 6.94196518145641 -0.390168869868828 2.31868357970948e-06 118.254548772379 25.5845863861623 4.62210125219529 5.8741076996035e-06 -23.2856867544184 48.1884947502235 -0.48322087824315 0.629327642744529 SNAPC4 essential 0.0200241513943711 1 0.0614314183224534 4.62210125219529 -0.48322087824315 0.379782506618428 13.348652679989 9.94359630661466 1.34243710910802 0.180577762261211 -5.41739025347195 45.1010800460794 -0.120116641285243 0.904479751821015 TMEM52B other 1 1 1 1.34243710910802 -0.120116641285243 3.35233294320077e-21 379.147914900075 45.2792811674142 8.37354094686762 2.99395766445991e-15 -243.362186590608 85.2833956311273 -2.85357055485 0.00465542069001594 PMPCA essential 4.9758677875929e-17 1 4.39303408106202e-11 8.37354094686762 -2.85357055485 4.72626442521741e-17 258.546930707857 35.6853459233481 7.2451849356656 4.46117694606961e-12 -178.01627512575 67.2132462386511 -2.64852964389899 0.00855669927116818 SDCCAG3 other 6.57517906836246e-13 1 6.18943689497698e-08 7.2451849356656 -2.64852964389899 0.0590308824890584 14.5675130775938 8.84051022739003 1.6478136106285 0.1005455642818 -17.4921621621621 17.2286617264872 -1.01529430665354 0.310867816601636 AK8 other 1 1 1 1.6478136106285 -1.01529430665354 0.00110455551226119 26.9584241499565 11.3159398618851 2.38234070514631 0.0178904267103424 -40.0394594594594 22.052856111592 -1.81561332721945 0.0705307610543487 SPACA9 other 1 1 1 2.38234070514631 -1.81561332721945 1.18943013560044e-08 146.256382530721 29.1482073677745 5.01768018476561 9.47838350704607e-07 -80.9262573096605 55.2631433593541 -1.46438027933788 0.144249126657999 TSC1 ts 0.00012056063854446 1 0.0105314319146789 5.01768018476561 -1.46438027933788 0.179184273020417 17.4469415625776 10.1435394592226 1.72000529329184 0.0865731035369392 25.317595821323 19.1933282683827 1.31908314531508 0.188254794937072 GFI1B other 1 1 1 1.72000529329184 1.31908314531508 4.94378341473814e-15 85.1193052959542 10.1327030338363 8.40045395702544 2.49625393708093e-15 2.32817875383606 43.8459700130578 0.0530990363114946 0.957691976193618 BORCS5 other 6.54655799779625e-11 1 3.66774590975301e-11 8.40045395702544 0.0530990363114946 0.000425640591558979 81.2733263458093 24.6327205906593 3.29940519751716 0.00109862632716434 -39.2773116720087 46.2208042623098 -0.849775599946386 0.396199954780443 FAM69B other 1 1 1 3.29940519751716 -0.849775599946386 6.82051919033871e-18 228.49148723698 32.5450083515799 7.02078440935129 1.83762896483699e-11 -206.057179642412 61.3918196491499 -3.3564273028559 0.000904787793959093 ZMYND19 other 9.64489618705796e-14 1 2.51001740307085e-07 7.02078440935129 -3.3564273028559 0.0569789170214088 31.0449369884869 27.9119777011953 1.11224426018216 0.267015209191717 -43.9491961635471 43.6727385995816 -1.00633020902353 0.315151138297576 STOX1 other 1 1 1 1.11224426018216 -1.00633020902353 0.167926662369223 22.2913557723842 61.9694007724603 0.359715528866154 0.719353003905095 -126.875881436537 98.2300942482024 -1.29161925790231 0.197640470530848 RET other 1 1 1 0.359715528866154 -1.29161925790231 1.08318226576701e-12 1068.60637535816 225.289150414338 4.74326603563841 3.39908538316465e-06 -707.554441260748 352.500789470961 -2.00724214638684 0.0457130739786924 DDX21 essential 1.33307241447945e-08 1 0.0362240529283857 4.74326603563841 -2.00724214638684 4.88101668805675e-16 375.236025205486 68.5877924383813 5.47088646339791 1.05861249096142e-07 -277.078190182149 108.837130482923 -2.54580572781294 0.0114849599971358 BMS1 essential 6.62598015403704e-12 1 0.00125000962932725 5.47088646339791 -2.54580572781294 2.34789509975435e-11 118.83013081917 26.5090834462533 4.48261936555053 1.09525138740972e-05 -67.5801281005665 36.7457975199323 -1.83912536022408 0.0670070957233131 STK32C other 2.74298957236535e-07 1 0.112120884529134 4.48261936555053 -1.83912536022408 1.39704455348123e-15 254.529312160367 39.0275051222016 6.52179306269755 3.37080734968066e-10 -155.153445626072 84.0492855616686 -1.84598173071005 0.0659813851999253 METTL17 essential 1.87483379077181e-11 1 4.42688129233561e-06 6.52179306269755 -1.84598173071005 0.0622354153757024 0.844788975980587 9.57689967413606 0.0882111126487076 0.929773794810933 -41.2649835493558 20.6247253824332 -2.00075311473008 0.0464126756847263 SLC39A2 other 1 1 1 0.0882111126487076 -2.00075311473008 0.168001593779453 31.5449796860066 25.8328068531853 1.22112087413826 0.223097662786866 -35.8771026770613 55.5173993893045 -0.646231687213596 0.518674184030551 RNASE7 other 1 1 1 1.22112087413826 -0.646231687213596 0.00752993369355404 149.926389596648 51.1430183849895 2.93151234188109 0.00365987873470152 49.6718887731489 109.911686863555 0.451925452066001 0.651682853926697 ARHGEF40 other 1 1 1 2.93151234188109 0.451925452066001 8.76478346058867e-07 136.479573046924 54.1920526471896 2.51844258300118 0.0123616820512282 -320.786306937067 114.903894874446 -2.79177922808957 0.00561348544834755 ZNF219 other 0.00783834584880445 1 1 2.51844258300118 -2.79177922808957 7.88039408417909e-07 166.419940273038 75.2202513935673 2.21243531083532 0.0277643428481034 -299.196296928327 105.915443209009 -2.82485998135236 0.00507905193053914 CASP7 other 0.00707501780877599 1 1 2.21243531083532 -2.82485998135236 0.108220637888871 -1.90613458158045 3.74583181202664 -0.508868170605119 0.611255641082826 -14.165491497304 6.95626977699237 -2.03636315890967 0.0426789172709782 PPP1R36 other 1 1 1 -0.508868170605119 -2.03636315890967 0.0574353208772009 -47.6841385284835 62.7347789839506 -0.760090962314261 0.447868348603517 -243.418924682707 102.18127106833 -2.38222643090758 0.0179061930973357 BTNL9 other 1 1 1 -0.760090962314261 -2.38222643090758 0.0542770199376546 17.9762041284407 43.9971301057033 0.408576743193314 0.683171779555314 -107.504587155963 62.0565130747496 -1.7323659005215 0.0843420030832261 VWA2 other 1 1 1 0.408576743193314 -1.7323659005215 1.04444692721133e-16 268.751794046807 40.5726814878599 6.62395937836207 1.87478863920932e-10 -176.326552948667 86.7089391264716 -2.03354526909251 0.0429716526784004 METTL3 essential 1.44029231262442e-12 1 2.48503234127196e-06 6.62395937836207 -2.03354526909251 2.95302718652146e-05 107.097715460118 26.5525349578476 4.03342715225258 7.1529836427459e-05 8.82666211104687 54.8478481019872 0.160929962003871 0.872268464746398 SALL2 other 0.231458270879552 1 0.681607811317257 4.03342715225258 0.160929962003871 0.0605856497294776 12.4254588862047 6.22040060471697 1.99753354740246 0.0467972760532219 1.9222921994658 8.68954869154198 0.221218876572597 0.82509366623928 PRAP1 other 1 1 1 1.99753354740246 0.221218876572597 5.67018069253273e-09 215.036048951049 40.1417093360095 5.3569230734813 1.814097248629e-07 11.7399300699296 56.8146390628005 0.206635653479251 0.836450153667001 TRUB1 other 5.86013174573258e-05 1 0.00211160919740416 5.3569230734813 0.206635653479251 4.30481379723145e-22 6.74933766761478 1.43547954291397 4.7017999670785 4.10397951509737e-06 -14.0526010564812 2.26557299776759 -6.20266973093698 2.05698751615523e-09 ERICH6B other 6.44904154963244e-18 3.27410702946428e-05 0.0434857669419718 4.7017999670785 -6.20266973093698 9.30452491391946e-10 96.6245448645319 20.1861100350385 4.78668473999269 2.78656796557658e-06 -71.3265810113632 37.0080173019214 -1.92732781195657 0.0549801274768358 ZFYVE1 other 1.00674959568609e-05 1 0.0299277399502925 4.78668473999269 -1.92732781195657 0.0014498796817955 27.9494239725469 7.97312950388949 3.50545215136823 0.000532647096651929 12.8367195940119 11.2679935290597 1.1392196455302 0.255610167911069 C10orf82 other 1 1 1 3.50545215136823 1.1392196455302 0.00204802637152483 45.5489419070185 27.6150072614157 1.64942712039987 0.100210291864518 -64.3026844967365 39.0267990724061 -1.64765458672223 0.100574010682045 HSPA12A other 1 1 1 1.64942712039987 -1.64765458672223 4.4719819403319e-07 2.5344431041352 6.64714138706211 0.381283164680113 0.703289710047616 -49.2545699995748 10.5878608429773 -4.65198501661876 5.12995441961909e-06 FRAT1 other 0.00409991304289629 0.0793706547803465 1 0.381283164680113 -4.65198501661876 5.85499215430935e-08 133.731738111624 28.5601558303544 4.68245827879869 4.47196059097736e-06 -41.9672324573904 45.4918795881351 -0.922521400244276 0.35707125189948 UBTD1 other 0.000568812487791153 1 0.047210487958948 4.68245827879869 -0.922521400244276 0.813408885314088 -0.909309445033232 4.00826421415911 -0.226858659122599 0.820703428467233 -4.05928007546326 6.38454054911557 -0.635798307526699 0.525440509070958 ANKRD2 other 1 1 1 -0.226858659122599 -0.635798307526699 0.0083008776977108 106.979776769479 38.0800027610569 2.80934267365346 0.00533128305543536 -41.0579074519856 89.5814948973384 -0.458330233258984 0.647088025241961 E2F7 other 1 1 1 2.80934267365346 -0.458330233258984 0.0219184126117877 43.1978057115448 17.7879036252155 2.42849335265731 0.0158150810923135 3.10960426477091 31.4577952333872 0.0988500383355087 0.92133068662341 ARHGAP42 other 1 1 1 2.42849335265731 0.0988500383355087 3.5630229567073e-19 137.056646184292 17.244770931295 7.94772205037344 5.02894178918321e-14 -58.2957078369646 33.7854387328414 -1.72546842732866 0.0855746823272513 ISCA2 essential 5.14785556785071e-15 1 7.24670511821301e-10 7.94772205037344 -1.72546842732866 4.19348721861768e-05 422.046358746693 118.010303740724 3.57635177072298 0.000413517272669243 -227.914489598452 251.150927835816 -0.907480181588043 0.364971224391882 LARGE2 other 0.323653343532912 1 1 3.57635177072298 -0.907480181588043 1.77009343947594e-07 349.628568466996 78.0670300686133 4.47856884218224 1.11163671964307e-05 -201.502850979078 166.342742094828 -1.21137146377091 0.2268161541849 PACSIN3 other 0.00166831306670607 1 0.113720436419486 4.47856884218224 -1.21137146377091 3.0866130124884e-20 317.474575833642 32.537797084214 9.75710110343235 1.80516296268288e-19 73.1780304493103 71.1603441714384 1.02835408261954 0.304700262285488 TTC7B other 4.52374003110299e-16 1 2.75558126253542e-15 9.75710110343235 1.02835408261954 1.00218377225476e-06 150.859144734786 43.7253263900407 3.45015480019715 0.000649956454768763 -202.99999479259 95.1131223030619 -2.1343006083405 0.0337190422411273 SLC39A13 other 0.00892143994061183 1 1 3.45015480019715 -2.1343006083405 2.74082258929149e-16 677.051551186933 102.907979119968 6.57919392623227 2.44522774377941e-10 -568.932698953756 221.355409262344 -2.57022270587241 0.0106999958568521 PSMC3 essential 3.74341549245431e-12 1 3.22647800791693e-06 6.57919392623227 -2.57022270587241 4.26176539220531e-05 20.3082409157366 5.30847322105875 3.82562745822539 0.000162090165445401 -6.18201894030084 11.3544962380045 -0.544455589285332 0.586577365938237 AGBL2 other 0.328667347046874 1 1 3.82562745822539 -0.544455589285332 4.13170982947973e-08 406.75845687306 89.207965251925 4.55966522411274 7.75349938789425e-06 -319.848128688464 190.984550766294 -1.67473299492093 0.0951359353974381 TC2N other 0.000405362051370257 1 0.0803029931604207 4.55966522411274 -1.67473299492093 2.88570739786608e-33 618.164840116829 52.9829426074083 11.6672425066552 8.97706037983752e-26 -252.996679328714 114.426229458605 -2.2110024993897 0.02786764683203 CPSF2 essential 4.5490291419961e-29 1 1.40544857306736e-21 11.6672425066552 -2.2110024993897 1.11995665716328e-18 8.60247300872301 0.875255286625929 9.82853019018619 1.07116612108211e-19 11.316571035321 5.4912908942405 2.06082162705865 0.0402742526251954 SMCO2 other 1.60444990705212e-14 1 1.63759876591033e-15 9.82853019018619 2.06082162705865 0.000230597693461778 76.8363591136251 29.3049540632714 2.62195801255072 0.00923512982986601 -100.63640166848 58.9061690274714 -1.70841871623916 0.0886994845791182 MOAP1 other 1 1 1 2.62195801255072 -1.70841871623916 7.21978406120553e-07 45.5725083986563 9.48054001848193 4.80695280119218 2.5340707582499e-06 -3.3412304031355 19.2960664598383 -0.17315603727266 0.86265709166117 IFI27L1 other 0.00650358148233394 1 0.0272894079955931 4.80695280119218 -0.17315603727266 0.00812085601910762 1545.23579523051 624.406977558282 2.47472538066934 0.0139416211691686 -778.744485424582 1270.87681856341 -0.612761578502053 0.540544096182592 IFI27 other 1 1 1 2.47472538066934 -0.612761578502053 0.684334790946315 -6.9779779967439 29.1969541428342 -0.238996778999857 0.811288056470779 -55.7116680247894 64.7523446222186 -0.860380706672866 0.390336945809317 CLMN other 1 1 1 -0.238996778999857 -0.860380706672866 0.472706989952425 9.21598141844627 9.59894550557664 0.960103525235362 0.337891690616794 -11.4534645155274 25.9013945654015 -0.44219489752211 0.658714371102902 PDZRN4 other 1 1 1 0.960103525235362 -0.44219489752211 0.00231320058456997 169.60251896303 91.0854319227633 1.86201586118454 0.0636752237773369 -254.391743890674 170.604059280669 -1.49112362837839 0.137083585464322 NELL1 other 1 1 1 1.86201586118454 -1.49112362837839 1.27926942191386e-05 27.4196810942711 21.5405034733638 1.27293594266157 0.204131698513557 -114.00463005299 36.2429736592492 -3.14556501695595 0.00184231254061758 PTER other 0.103774335505652 1 1 1.27293594266157 -3.14556501695595 0.248622258943823 0.999448765847995 6.92034579973002 0.14442179549568 0.885274750305206 -15.169473877626 11.719810792301 -1.29434460559647 0.196648264764693 CACNB2 other 1 1 1 0.14442179549568 -1.29434460559647 0.000398787921522773 39.5968884339041 12.1923435804157 3.24768475992653 0.00130945644220181 -2.57802997106395 20.7069911009345 -0.124500462597272 0.901010993011528 HACD1 other 1 1 1 3.24768475992653 -0.124500462597272 3.74236438643857e-11 314.284440272902 67.0095187307875 4.6901462094594 4.34023680216596e-06 -218.49630799594 113.076572806297 -1.9322862603046 0.0543701937943142 ARL5B other 4.33702608744366e-07 1 0.0458980041829051 4.6901462094594 -1.9322862603046 0.00114461065163154 48.5651054253261 26.9375121759232 1.8028801289502 0.0725303016025631 -85.3449237899609 47.9520340946393 -1.77979777920415 0.076242125066404 SMCO4 other 1 1 1 1.8028801289502 -1.77979777920415 9.87247441807181e-10 122.790637083132 22.6017833395965 5.43278533548335 1.24592698747808e-07 -15.2050183836221 40.2339116627364 -0.377915488582846 0.705792517476264 CEP295 other 1.0665234113843e-05 1 0.00146533472997297 5.43278533548335 -0.377915488582846 0.0196454842134523 89.6130833242156 47.8597110429734 1.87241170854023 0.0622344506528245 -117.927536185248 109.131473132133 -1.08060060769513 0.280842659183918 ABTB2 other 1 1 1 1.87241170854023 -1.08060060769513 8.09915695745235e-19 90.309503299943 13.6611101312242 6.61070018706088 2.00291252338467e-10 -69.0408370878614 21.7600205272476 -3.17282959367659 0.00168210542460417 R3HCC1L other 1.16279596438143e-14 1 2.65205647221364e-06 6.61070018706088 -3.17282959367659 0.0032817855642596 341.027457399319 162.44731723572 2.09931110714786 0.0367213539592048 -354.881320791865 289.573136438249 -1.2255326069155 0.221446510714747 AMOTL1 other 1 1 1 2.09931110714786 -1.2255326069155 0.510156025773376 202.78428731762 250.35401329539 0.809990160127199 0.418651293809643 -83.5615816282473 347.820000703072 -0.24024375096124 0.810321599025096 HTRA1 other 1 1 1 0.809990160127199 -0.24024375096124 0.791378719970806 1.73251761132112 3.05119396669786 0.567816281177341 0.570629844283194 3.43287295479149 5.95178810923403 0.576780102346971 0.564566795063568 LIPC other 1 1 1 0.567816281177341 0.576780102346971 4.14559654825806e-16 284.964572426179 37.8787938573634 7.52306352465296 8.04554347525635e-13 -23.4407688815143 67.5214668264323 -0.347160243745446 0.728742382746056 CEP57 other 5.63842586528579e-12 1 1.13562846153243e-08 7.52306352465296 -0.347160243745446 0.00219618475781247 25.2765246490882 11.5410465664105 2.1901414662561 0.0293631452971307 -51.1657782648149 25.6601390653889 -1.99397899342754 0.047152661693088 TCP11L2 other 1 1 1 2.1901414662561 -1.99397899342754 0.00416491912477147 69.4786869421669 69.0096605377402 1.0067965325546 0.314937327425829 -268.087898585193 120.595354825298 -2.2230366913681 0.0270445311266276 SPRED1 other 1 1 1 1.0067965325546 -2.2230366913681 0.0355542390068388 55.6436086611372 29.6140171976304 1.87896185410434 0.0613189649630819 -30.6551723193464 51.5682150156601 -0.59445866625473 0.552699515160746 GPR176 other 1 1 1 1.87896185410434 -0.59445866625473 0.0799167804718002 153.064626865671 73.786128267005 2.0744363535621 0.0390541446431877 33.1465671641788 134.448685069292 0.24653693821621 0.80546732097389 JAM3 other 1 1 1 2.0744363535621 0.24653693821621 0.127313199491881 15.3476412567825 7.89043070358695 1.94509550027549 0.0528801620989298 21.4878998367732 14.3892598410221 1.49332905751787 0.136607021584592 GLB1L3 other 1 1 1 1.94509550027549 1.49332905751787 0.228673241316149 -23.7650707266021 48.0309046035703 -0.494787073505077 0.621155805042754 -146.513491871752 87.7668804321811 -1.66934829118103 0.096216017989621 ADAMTS15 other 1 1 1 -0.494787073505077 -1.66934829118103 5.89275572889725e-06 311.161343594849 94.9102435541506 3.2784800875294 0.00118599646746817 -212.47246748094 167.99034122986 -1.26478978449253 0.207079179489642 GPT2 other 0.0491573682904609 1 1 3.2784800875294 -1.26478978449253 5.00130600006123e-10 190.948945952059 34.2510745645051 5.57497679649275 6.07288899848133e-08 -76.828815875111 75.1515697447798 -1.0223181782633 0.307559178553266 AMN other 5.49593516346728e-06 1 0.000726196066438398 5.57497679649275 -1.0223181782633 0.449651121355667 1.56707228741116 44.8321107330131 0.0349542384195 0.972141774615741 -102.21361040585 88.9433632891873 -1.14919884548908 0.251479817387604 RAB8B other 1 1 1 0.0349542384195 -1.14919884548908 0.00899580829214697 89.8151444474655 30.1098485564748 2.98291584824832 0.00311617896605435 4.95066457621738 64.95125913019 0.0762212256161831 0.939299543573185 IKBIP other 1 1 1 2.98291584824832 0.0762212256161831 8.18294871161472e-19 79.7506979903247 11.1316712464293 7.16430590023996 7.28961527652601e-12 -42.1514880616809 19.3151506382212 -2.18230180293136 0.0299397006916165 RPUSD2 other 1.17474411703941e-14 1 1.00603980431336e-07 7.16430590023996 -2.18230180293136 1.39271312381931e-16 270.083823742086 54.5636469355768 4.94988584727435 1.30409834072649e-06 -272.796908478047 78.2330669139905 -3.48697704485956 0.000569440502426756 HIF1AN other 1.91511981656393e-12 1 0.0143424735513099 4.94988584727435 -3.48697704485956 5.72149130180524e-14 540.317033963353 76.7678190268086 7.03832726802706 1.58439496981087e-11 50.9955479413947 110.06929082025 0.463304047490174 0.643516936189979 NDUFB8 essential 7.34925557716884e-10 1 2.16808607668919e-07 7.03832726802706 0.463304047490174 6.78228608730836e-08 72.0263498221786 26.3738296309714 2.73097805021067 0.00673053300576102 -144.066638744379 45.8628367946584 -3.1412500580679 0.00186940490029751 ZFYVE19 other 0.00065632182466883 1 1 2.73097805021067 -3.1412500580679 0.778402533939375 -3.64910685418687 5.54550143802604 -0.658030097903247 0.51107944083673 -5.39842441142757 9.6433635522565 -0.559807206497401 0.576075069293948 PPP1R14D other 1 1 1 -0.658030097903247 -0.559807206497401 7.97274771770563e-07 385.122817652763 327.819733779583 1.1748005930348 0.241109540787794 -2267.53076778944 570.062943409088 -3.97768491007178 8.94424098468433e-05 SPINT1 other 0.00715474380186903 1 1 1.1748005930348 -3.97768491007178 0.182666545829766 380.297069964349 323.987877006206 1.17380030845125 0.241509370755632 1104.5980098163 614.464599346944 1.79765931347432 0.0733482233007673 FBN1 other 1 1 1 1.17380030845125 1.79765931347432 0.207671143642971 3.03571376162708 5.54055899781283 0.547907487823059 0.584208100821773 -22.4843152554851 15.631647063267 -1.43838427035122 0.151483158029351 AVPR1A other 1 1 1 0.547907487823059 -1.43838427035122 9.17214104763356e-09 7.42976121733069 1.26893872368173 5.85509849977138 1.37031220564269e-08 -1.29126457011803 2.61863597903819 -0.493105792654808 0.622335697495058 DEPDC4 other 9.36750765194816e-05 1 0.000169055416810139 5.85509849977138 -0.493105792654808 1.53779006270661e-15 158.970637962128 65.7023107185307 2.41955931570139 0.0162077445574609 -654.936541929666 117.570019940508 -5.57060841072473 6.19148027621308e-08 BRD7 other 2.06186891607703e-11 0.000979739838907958 1 2.41955931570139 -5.57060841072473 0.00165532734551526 541.616701522626 167.073700338714 3.24178311981234 0.00133870129405139 -10.9763339974185 392.677169780498 -0.0279525647074266 0.977720865433181 CKB other 1 1 1 3.24178311981234 -0.0279525647074266 4.86375041096771e-21 202.078686833572 21.5080431866235 9.39549381969118 2.65894827032165e-18 -12.7575785163552 50.5508497682028 -0.252371198008622 0.80094832931461 TRMT61A other 7.20564623384867e-17 1 4.02644536574807e-14 9.39549381969118 -0.252371198008622 1.52288989135395e-13 79.421026586123 24.711535635471 3.21392517881899 0.00146712603004737 -148.669542563962 35.2722395665008 -4.21491644395494 3.40356074780419e-05 BTRC other 1.930110648302e-09 0.516354201049374 1 3.21392517881899 -4.21491644395494 1.56130150983026e-17 103.486806054481 23.9066102513541 4.32879462903442 2.10915436430848e-05 -139.834553889992 33.4746749130053 -4.177323730653 3.97722274679368e-05 POLL other 2.19362862131152e-13 0.602429929456839 0.210809978712632 4.32879462903442 -4.177323730653 1.20708130479768e-27 453.063507581663 41.2482106955927 10.9838342061725 2.09693511327786e-23 -63.0174190650947 96.9466205729439 -0.650021823274176 0.516236998854342 BAG5 other 1.87339018504599e-23 1 3.26178256870371e-19 10.9838342061725 -0.650021823274176 4.68481911001656e-09 128.29856553135 27.8169177278282 4.6122495233539 6.13831378168993e-06 -32.5585514058525 38.94999199931 -0.835906497912228 0.403941205150383 DPCD other 4.86518464575219e-05 1 0.0640962725084063 4.6122495233539 -0.835906497912228 3.48928825404631e-05 161.046226713908 35.2588706732863 4.56753786036384 7.51008609362301e-06 79.0139425591307 66.3216918004545 1.19137404993926 0.234552991367432 LARP6 other 0.271431733282262 1 0.0778871028769643 4.56753786036384 1.19137404993926 6.5551237836025e-16 567.981216059634 89.2994072711552 6.3604141776101 9.00743683580593e-10 -502.326170793275 181.713268076882 -2.7643890625573 0.00611105167552106 API5 other 8.86908247921418e-12 1 1.16574247529e-05 6.3604141776101 -2.7643890625573 0.451895968957763 1.25605800888578 13.7097891420573 0.0916176022746105 0.927074078895743 -33.9166563086253 31.411297533868 -1.07975979890853 0.281273376207349 ASPG other 1 1 1 0.0916176022746105 -1.07975979890853 2.61084510647042e-10 70.3442652572611 24.0407980264287 2.92603703004907 0.00372179672908427 -141.037684520135 42.0872935415451 -3.35107517381497 0.000918613915411759 ZNF319 other 2.91135337822517e-06 1 1 2.92603703004907 -3.35107517381497 9.37323045876993e-15 102.299905018205 22.8718898526349 4.47273512059257 1.13557336806466e-05 -101.723571315498 32.0258317433209 -3.17629756287946 0.00166348813434272 HPS6 other 1.23042396232273e-10 1 0.116123732618292 4.47273512059257 -3.17629756287946 1.99039901445098e-06 12.0671081829667 3.56772074601904 3.38230176687218 0.000826069399583019 -15.7368456218212 6.63040178004008 -2.37343771069724 0.0183287997121314 SENP8 other 0.0173085098296657 1 1 3.38230176687218 -2.37343771069724 5.35114970079129e-12 846.500240774107 190.66986152829 4.43961218615828 1.31129900565836e-05 -603.638289443799 268.238915059429 -2.25037552552754 0.025224278216971 NOLC1 essential 6.4047910768771e-08 1 0.133398447845625 4.43961218615828 -2.25037552552754 1.92856794478038e-08 77.0860454748101 17.6722738754397 4.36197662044733 1.8523380659121e-05 -70.1417744092737 36.4711729512566 -1.92321136759208 0.0555330995167336 ALKBH3 other 0.000193107508310859 1 0.186104405482188 4.36197662044733 -1.92321136759208 3.24587081615063e-16 560.812691150206 75.2155299809963 7.45607577706225 1.20643970890703e-12 -200.23115717746 143.744721635064 -1.39296354606886 0.164772425535328 COPS2 essential 4.426069444903e-12 1 1.69685745057774e-08 7.45607577706225 -1.39296354606886 0.647432327682093 29.1873281937873 46.9764741434422 0.621317983649945 0.534910771339658 -22.9345140009731 87.9384465665625 -0.260801900606846 0.794442620703424 GABRB3 other 1 1 1 0.621317983649945 -0.260801900606846 1.25084810204466e-11 506.495815950754 156.857482577527 3.22901915565562 0.00139457413797525 -783.285779124596 246.254953301469 -3.18079197442857 0.00163881696577748 SGPL1 other 1.4790027958576e-07 1 1 3.22901915565562 -3.18079197442857 8.30758914593715e-26 191.80807608879 17.2789757467155 11.1006623830264 8.05154508263395e-24 -152.88271564671 72.0110337201983 -2.12304570214534 0.0346632200511527 FRS2 other 1.27887027312557e-21 1 1.25386711571859e-19 11.1006623830264 -2.12304570214534 1.2730522912409e-34 1775.37265418071 124.402811690209 14.2711618014052 8.73974898774316e-35 147.479384293875 518.455213944841 0.284459255741164 0.776277307672928 CCT2 essential 2.01002226264026e-30 1 1.38533761204717e-30 14.2711618014052 0.284459255741164 4.76728612957753e-10 280.428558616097 84.8899623693803 3.30343601044224 0.0010830715723385 -342.827302993654 133.271128514402 -2.57240489230649 0.0106304418623466 PCBD1 other 5.24353801392233e-06 1 1 3.30343601044224 -2.57240489230649 0.236737126617807 2.63607634902412 5.64062170003838 0.467337908692969 0.640630936979117 -12.939128077561 10.9386934245099 -1.18287692829646 0.237887039450338 C16orf71 other 1 1 1 0.467337908692969 -1.18287692829646 0.537121095694037 57.6532411197288 53.9892232699514 1.0678657263035 0.286524452880279 24.2500063294877 97.9485257135916 0.247579084553007 0.80464619601577 CLMP other 1 1 1 1.0678657263035 0.247579084553007 0.255098052020774 -3.46154917983587 14.8638498301412 -0.232883756186534 0.816026177893257 -41.1901305917357 26.7281111719847 -1.5410789908308 0.124455855115494 SCN3B other 1 1 1 -0.232883756186534 -1.5410789908308 2.93240283448335e-15 253.840395481756 35.1139818284319 7.2290404637682 5.0830327533414e-12 -173.193034645286 72.5604689016846 -2.3868786581293 0.0176859837605488 COX11 essential 3.90302817269734e-11 1 7.04152527320385e-08 7.2290404637682 -2.3868786581293 3.25602070958898e-11 69.9664947901722 15.8354080630791 4.41835755109474 1.43564421968531e-05 -80.3118363518784 28.5280004832649 -2.81519331854299 0.00522984963281767 ZNF202 other 3.78382166661336e-07 1 0.145473828780712 4.41835755109474 -2.81519331854299 2.96326940849403e-10 51.1166230334468 8.83332723237953 5.78679151000692 1.97760908672321e-08 -15.2527678549582 16.881409523414 -0.903524544784191 0.367050002644984 FAM227B other 3.29485925530451e-06 1 0.000241940695669717 5.78679151000692 -0.903524544784191 4.49577497232867e-12 52.7166436555499 8.60806357333307 6.12410017728736 3.23440576011582e-09 -42.0936044878673 17.8576374643789 -2.35717656223185 0.0191339168487463 STXBP4 other 5.39537954429164e-08 1 4.10122650382686e-05 6.12410017728736 -2.35717656223185 0.69291176772741 -3.52243386459929 58.5100835049709 -0.0602021677904464 0.952051600769968 57.0845864789843 84.9779971847013 0.6717572591751 0.502473069996567 CYYR1 other 1 1 1 -0.0602021677904464 0.6717572591751 1.27194119304675e-17 235.014229990122 33.4638395191538 7.02293082225687 1.77595020497394e-11 -123.654813921953 58.9166419179161 -2.09880960449564 0.0367659473281702 CUL5 other 1.78974845273608e-13 1 2.42683595509688e-07 7.02293082225687 -2.09880960449564 4.12554027674625e-08 116.28386760119 79.4125486128775 1.46430091506135 0.144266528878205 -480.72025948459 119.670248511434 -4.01704070530661 7.63161081145848e-05 WBP1L other 0.000404798011954342 1 1 1.46430091506135 -4.01704070530661 0.000350359477312854 21.6271154279477 22.2113356870344 0.973697202756352 0.331072027102968 -90.722744037666 33.4712348094476 -2.71046899088583 0.0071460215316161 BORCS7 other 1 1 1 0.973697202756352 -2.71046899088583 0.682247871734285 -151.95899251747 184.23247058008 -0.824821987345698 0.410195413860018 -208.896202128119 345.16539477507 -0.605206099134728 0.545546658123317 C2 other 1 1 1 -0.824821987345698 -0.605206099134728 0.478963385948178 -5.83531062193655 20.8795768037432 -0.279474563914074 0.780124397905186 -84.0593394412789 69.1792373171251 -1.21509491433017 0.225539017054272 PLEKHF1 other 1 1 1 -0.279474563914074 -1.21509491433017 0.63987640543644 -47.0490906485938 91.7775400675317 -0.512642751309026 0.608621928136305 -177.130254259487 195.702504140664 -0.905099579779379 0.36622255462649 TMEM100 other 1 1 1 -0.512642751309026 -0.905099579779379 2.33215343692454e-15 469.68895088995 108.537446746785 4.32743688900038 2.12134768093358e-05 -548.370479732019 169.655097573361 -3.23226644866888 0.00137940673087833 ANAPC16 other 3.11179233088841e-11 1 0.211965060278883 4.32743688900038 -3.23226644866888 3.08417743067458e-07 -7.70665562571222 46.8991191721926 -0.164324101640733 0.869597606270474 -322.922242273958 71.1857216094778 -4.53633446389006 8.582259209721e-06 SMPD1 other 0.00286365874438134 0.132201120866542 1 -0.164324101640733 -4.53633446389006 0.000199021621119051 102.814460200807 51.2615508759036 2.00568376188432 0.0458766340433901 -129.819286868315 77.8072286714879 -1.66847334219328 0.0963682476990861 APBB1 other 1 1 1 2.00568376188432 -1.66847334219328 2.16122777033025e-07 12.874036946776 4.46682307188808 2.88214615613469 0.00426724052844143 -14.3336577573427 6.98834573756623 -2.05108022636765 0.0412241084382117 NUDT13 other 0.00202550266635351 1 1 2.88214615613469 -2.05108022636765 1.49357658259996e-09 6.11695935803213 1.2816078766841 4.77287902900421 2.98421953576505e-06 -3.70186078047311 2.25640671945486 -1.64059996300998 0.102049213008135 C11orf65 other 1.59932180464804e-05 1 0.0319729281061868 4.77287902900421 -1.64059996300998 8.8716163408658e-16 558.919319492396 81.9595061116125 6.81945690023143 6.20659520114317e-11 -420.272453712006 190.223441789891 -2.20936205210824 0.0280081632256712 TRIM44 other 1.1967810443828e-11 1 8.35531845977893e-07 6.81945690023143 -2.20936205210824 7.24682293894845e-06 152.811277300485 112.839900210607 1.35423087946085 0.176782587385499 -503.140272633585 171.273786472224 -2.93763735243385 0.00358949833844943 ILK og 0.0600181875803711 1 1 1.35423087946085 -2.93763735243385 1.54156930953503e-14 408.315792878582 119.228644387635 3.42464510081209 0.000710215097127358 -722.497545037649 180.970927323641 -3.99234040363602 8.41522812969566e-05 TAF10 essential 2.0111313212194e-10 1 1 3.42464510081209 -3.99234040363602 8.74377931919577e-07 502.715777352238 238.620720717636 2.10675659615961 0.0360511299871072 -955.913957057289 362.189919450131 -2.63926162966804 0.00878629071746267 TPP1 other 0.00782131060102061 1 1 2.10675659615961 -2.63926162966804 0.0359158896939875 94.5367844943578 99.4366238331254 0.950723997357447 0.342585418017429 -198.94327709347 150.929653838109 -1.31811921669722 0.188568641013254 DCHS1 other 1 1 1 0.950723997357447 -1.31811921669722 0.119419355825145 -11.5226056501146 6.10916956915745 -1.88611652036756 0.0603604903417202 -16.5978187075183 9.54168274963671 -1.73950645216644 0.0830938229077789 NETO1 other 1 1 1 -1.88611652036756 -1.73950645216644 0.000858308427757615 3.42837623001067 2.74255155711903 1.2500681057796 0.212357055858789 -9.16038820020995 4.34384205218006 -2.10882165837789 0.0358809768016566 MSS51 other 1 1 1 1.2500681057796 -2.10882165837789 0.000167941221969316 236.548480142902 217.000928419235 1.09008049811613 0.276656835909105 -951.896222431977 334.668243579091 -2.84429801959091 0.00479412153639699 CYB5A other 1 1 1 1.09008049811613 -2.84429801959091 0.0189554090337941 67.836942403806 81.4412165227454 0.832955907342814 0.405605794177379 -213.686637433891 128.99220807496 -1.65658562344877 0.098764864252283 USP54 other 1 1 1 0.832955907342814 -1.65658562344877 0.00930861477645749 24.7855686161299 12.6983851113875 1.95186776891048 0.052015137957188 -36.1849485792357 28.1611387778197 -1.28492490537122 0.199949006133077 RAG1 other 1 1 1 1.95186776891048 -1.28492490537122 5.03530422335248e-09 46.8653291281383 8.096497346423 5.78834613573278 2.01816605774718e-08 1.31032015657029 17.9555576072739 0.0729757429554553 0.941880888660023 C11orf74 other 5.22312107088353e-05 1 0.000246781345541325 5.78834613573278 0.0729757429554553 2.07503967261386e-09 5.65836742931581 0.887471593126969 6.37582934838375 7.96473203632275e-10 -0.0154688732730329 3.18868851086665 -0.00485117101288412 0.996132963293881 WDR88 other 2.20431464421771e-05 1 1.03270715582961e-05 6.37582934838375 -0.00485117101288412 2.93778402067214e-22 128.143990696668 22.2761889336639 5.75250960019538 2.52969978555896e-08 -168.629182893408 33.6397878176622 -5.01278973004911 1.00935900123637e-06 ATP9B other 4.40843870142062e-18 0.0158055526003603 0.000307889760900382 5.75250960019538 -5.01278973004911 3.7141013540417e-07 27.3172268399967 77.5849337112506 0.352094479343938 0.725040045159747 -519.921992987061 122.242704961009 -4.25319443931561 2.90110651534941e-05 PPFIBP2 other 0.00342625849910347 0.441142256724031 1 0.352094479343938 -4.25319443931561 6.52217316729038e-05 182.905907227873 97.537085915207 1.87524473908192 0.0618303453106384 -325.649360162983 153.67928598952 -2.11901921632555 0.0349950977040294 CYB5R2 other 0.4939241739589 1 1 1.87524473908192 -2.11901921632555 0.0491730984689081 -139.461471313128 72.4576622515759 -1.92473048369835 0.0553059966260197 -293.489608650617 128.319682351962 -2.28717530523197 0.0229537458681459 SERPINB7 other 1 1 1 -1.92473048369835 -2.28717530523197 1.08167523125744e-12 162.220479229577 21.2154558008698 7.64633485851982 3.74685077540665e-13 22.3283780900219 73.8594714630662 0.3023089340842 0.762651930016484 KIAA0355 other 1.33132587463166e-08 1 5.33176865340366e-09 7.64633485851982 0.3023089340842 4.73275333617531e-06 -0.349841986000282 30.8426029846736 -0.0113428164987932 0.990958220405373 -241.9241139749 54.6778826506524 -4.42453332585316 1.39786260557521e-05 SERPINB8 other 0.0398355848305875 0.214432123695237 1 -0.0113428164987932 -4.42453332585316 1.2713794520802e-06 161.966019517747 43.1086101851822 3.75716170904113 0.000210271878412628 -45.5553549870783 65.2579271955951 -0.698081550315519 0.485722541992507 TUB other 0.0112300947002244 1 1 3.75716170904113 -0.698081550315519 0.00410593191057941 27.8147704958446 18.8956385171637 1.47202067136177 0.142171372077048 -41.9431277452155 28.6464023561006 -1.46416737514976 0.144302980145288 RIC3 other 1 1 1 1.47202067136177 -1.46416737514976 0.283838171464226 2.5665164443152 6.34301077072441 0.40462117077914 0.686073994602301 -9.38523310557692 9.76255261954508 -0.961350322126536 0.337229874402394 LMO1 other 1 1 1 0.40462117077914 -0.961350322126536 1.1272282458075e-09 332.480876185383 60.0656507479536 5.53529133615039 7.31120641978235e-08 -175.317826727066 116.900533844121 -1.49971793080809 0.134847260754884 IDH3A other 1.21402482073468e-05 1 0.000870472236339287 5.53529133615039 -1.49971793080809 0.000578956473455326 313.902841254433 102.352959373267 3.06686629459997 0.00238194493378899 -179.18755848262 199.887147622916 -0.896443621381076 0.370811496701991 WDR72 other 1 1 1 3.06686629459997 -0.896443621381076 0.0286779617855883 140.222460174907 53.3670636436329 2.6275093775304 0.00908952796674007 146.016333447618 102.69773811957 1.42180671279842 0.156227975867542 CRABP1 other 1 1 1 2.6275093775304 1.42180671279842 0.0271980383081042 148.597050995395 56.5690335700422 2.62682675692889 0.00911283539010023 66.695914730752 135.915321970863 0.490716673908554 0.62402690996623 PLD4 other 1 1 1 2.62682675692889 0.490716673908554 2.9280165569867e-11 108.377590354144 21.4531637482864 5.05182320079953 8.05316099562054e-07 -158.242167932121 55.7399980489051 -2.83893386205866 0.00486911639164394 XRRA1 other 3.40850407398821e-07 1 0.00898813298721209 5.05182320079953 -2.83893386205866 2.11039158086173e-05 16.6390481196112 22.3402478011118 0.744801412578028 0.4570348097932 -110.722310814891 34.3839625337924 -3.2201730881388 0.00143668015265156 TRIM66 other 0.167966065920785 1 1 0.744801412578028 -3.2201730881388 9.03486522388651e-13 182.790967132167 29.1091988515086 6.27949151279008 1.34483542668279e-09 -139.857933867194 75.6320469197876 -1.84918879711827 0.0655194764782931 RNF169 other 1.11535411188879e-08 1 1.73053422705542e-05 6.27949151279008 -1.84918879711827 7.79568142216424e-05 1959.3585442224 588.518222044399 3.32930820292355 0.000990889735844728 -219.58419198641 905.790691194649 -0.242422663559061 0.808635364995261 RPL27A essential 0.585143847547648 1 1 3.32930820292355 -0.242422663559061 0.0527853150217047 64.6339879961956 138.84674497294 0.465505964931278 0.641941663578169 -352.799619681484 216.198259618415 -1.63183376362126 0.10387169159438 ST5 other 1 1 1 0.465505964931278 -1.63183376362126 0.000585077330164436 60.5258256141762 21.7570184582326 2.78189889530907 0.00578087795639617 -21.7411152357769 36.4211997118225 -0.596935724462685 0.551045019142634 CDYL2 other 1 1 1 2.78189889530907 -0.596935724462685 0.802683901205244 -6.06427888504816 12.0194591173243 -0.504538417731906 0.614300760915113 -28.2153570640582 54.3062764505394 -0.519559780346125 0.603802495379008 TMEM130 other 1 1 1 -0.504538417731906 -0.519559780346125 0.298535299815856 18.9986306439674 12.1938022495344 1.55805631870838 0.120395591087167 14.3726498889711 23.7081973897495 0.606231239460882 0.544872440259955 PRTG other 1 1 1 1.55805631870838 0.606231239460882 2.17228441171396e-17 285.779450261778 37.2494869516779 7.67203721845907 3.0047986295963e-13 4.93511267926136 62.3555569451954 0.0791447133348332 0.936975500558553 CENPN essential 3.04467383145828e-13 1 4.2827394867636e-09 7.67203721845907 0.0791447133348332 4.76535881252457e-06 79.3332381829597 27.8760783932061 2.8459253509021 0.00476529482059989 -70.8897246086459 43.4058402649067 -1.63318401800321 0.103587284693916 AKIP1 other 0.0400957290485817 1 1 2.8459253509021 -1.63318401800321 1.17869016465381e-26 311.781665324204 55.934744757212 5.57402499425912 5.97333528323052e-08 -520.52482533401 93.6346362688947 -5.55910554123579 6.4504343526158e-08 ATMIN other 1.82072269734073e-22 0.00102052321892735 0.000714649833285699 5.57402499425912 -5.55910554123579 0.000307273597267008 10.3366894885219 3.27594959500659 3.15532616993794 0.00178253439658781 -1.36275193051881 5.48393221592604 -0.248499047191212 0.80393513728247 C16orf46 other 1 1 1 3.15532616993794 -0.248499047191212 2.48136467605426e-18 199.746126778497 46.1953889972514 4.32394078963988 2.1530560919876e-05 -312.892135556387 71.9308378856695 -4.34990255575381 1.92800835922457e-05 TMEM41B other 3.53718534571535e-14 0.294599677289514 0.215004181345882 4.32394078963988 -4.34990255575381 0.0128785785688646 22.7026278695126 10.0142038550892 2.26704271233455 0.024169874955988 -3.86201737029187 16.7637546137715 -0.230379020647272 0.817969800657431 PKD1L2 other 1 1 1 2.26704271233455 -0.230379020647272 5.41624631125196e-16 132.394023500795 19.6031524357568 6.75371086026471 8.86768409839068e-11 -94.1894598000725 38.2774861669255 -2.46070129551661 0.0144952002798239 LEO1 other 7.34442999805766e-12 1 1.18693951656959e-06 6.75371086026471 -2.46070129551661 0.00100930822792427 32.9016021341978 13.3835157914481 2.45836764022959 0.0145805974103269 -16.5705626676629 20.839471766159 -0.795152720452907 0.427217973312461 ZNF143 other 1 1 1 2.45836764022959 -0.795152720452907 3.66723590464958e-22 303.577486625177 49.2656759319858 6.16204854358 2.61158921011284e-09 -347.482760126651 80.532229059572 -4.3148285373997 2.24591901924383e-05 TMX3 other 5.49718662106972e-18 0.342570028005261 3.32115799850049e-05 6.16204854358 -4.3148285373997 0.981118821747678 -43.7648618842558 409.705235118553 -0.106820362867933 0.915010526259789 82.6086132909195 1057.38200643621 0.0781256090874316 0.937785789010514 MFAP4 other 1 1 1 -0.106820362867933 0.0781256090874316 2.21549566427971e-14 476.714073482968 97.2622562850786 4.90132649283505 1.63800766679712e-06 -380.134011341643 151.447054372736 -2.51001257776907 0.0126537154506976 WEE1 essential 2.8792581652979e-10 1 0.0178952337597585 4.90132649283505 -2.51001257776907 2.09925822911766e-13 128.616584392396 22.8773760242997 5.62199896770432 4.68980301144315e-08 -103.98503308476 59.0427548614797 -1.76118193212223 0.0793353369376766 MAPK7 other 2.64926388514649e-09 1 0.00056427709833684 5.62199896770432 -1.76118193212223 0.0849812969872356 -64.8081161589644 29.2660793379965 -2.21444476420944 0.0276304024293387 -77.0675708718093 62.1656504029797 -1.23971309512939 0.216153969564959 PRKCB other 1 1 1 -2.21444476420944 -1.23971309512939 1.48749278805601e-15 63.147016573401 36.330068344197 1.7381474753952 0.0833291261724539 -331.971297785211 56.9145418308499 -5.83280277950458 1.56006513416658e-08 NDST2 other 1.99532282589833e-11 0.000247691541351628 1 1.7381474753952 -5.83280277950458 5.38458891005642e-23 1627.98595147095 150.3245495709 10.8298076137133 5.83681600814147e-23 -124.247629663922 662.814797379582 -0.18745451995811 0.851444035174605 MCM7 essential 8.12911387751218e-19 1 9.05932212623637e-19 10.8298076137133 -0.18745451995811 0.0380291675496716 -7.9311484889627 18.5723961783059 -0.427039592135502 0.66969464282779 -73.1960828682054 31.0237015403313 -2.35936007742498 0.0190267351760182 CCDC68 other 1 1 1 -0.427039592135502 -2.35936007742498 0.0646336825979791 4.94429189349145 5.9693010778555 0.828286566384369 0.408234406079669 64.7009813435202 27.9791745395633 2.3124692707439 0.0214985648973264 CLEC4E other 1 1 1 0.828286566384369 2.3124692707439 7.39979692999262e-17 222.157254278111 25.2026383402783 8.81484117966587 1.45892208943441e-16 -80.0099837990559 111.124108953766 -0.720005627512791 0.472139767550592 ZNF3 other 1.02487187480398e-12 1 2.1755446197646e-12 8.81484117966587 -0.720005627512791 4.69511154441521e-15 55.962088384599 6.68529958443866 8.37091706628402 3.04744526221852e-15 -6.01426344849685 29.4769916299772 -0.204032471291287 0.838480697064293 ZSCAN21 other 6.22102279635015e-11 1 4.47121168872702e-11 8.37091706628402 -0.204032471291287 1.11487937618154e-05 221.877275440977 46.2831609667995 4.7939092924128 2.69558034238804e-06 -1.20081798798225 216.352252267493 -0.00555029113585372 0.995575599620068 RIMKLB other 0.0908961155400809 1 0.0289774886806714 4.7939092924128 -0.00555029113585372 0.462104501711164 247.892439620081 247.893183112111 0.999997000756454 0.318200736765202 -630.94316340376 1158.78534153135 -0.544486662706624 0.586552715844494 A2ML1 other 1 1 1 0.999997000756454 -0.544486662706624 0.209844245589992 -8.8591227766387 11.2816060542655 -0.785271417387341 0.432975406483495 -34.3238480514559 19.5260538733301 -1.75784868126056 0.0798939404080746 BEAN1 other 1 1 1 -0.785271417387341 -1.75784868126056 3.52540309433286e-05 -17.4628769874632 30.2771182118476 -0.576768134446491 0.564571363896178 -216.569163339415 52.4032339447088 -4.13274424185192 4.77242558759705e-05 TK2 other 0.274170598646267 0.720922609262411 1 -0.576768134446491 -4.13274424185192 0.000613939095511636 383.889405210682 131.015680383924 2.93010274866142 0.00367492931285134 -351.862772603402 253.882917592445 -1.38592535464809 0.166900725127077 TMED3 other 1 1 1 2.93010274866142 -1.38592535464809 0.0044102047920853 5.31785003606265 241.560883081007 0.022014533016421 0.98245256301543 -1132.49766164701 404.688365563866 -2.79844383484824 0.00550354002776148 SEC11C other 1 1 1 0.022014533016421 -2.79844383484824 6.78896805710912e-19 153.993264887933 17.9325437653254 8.58736311496956 7.19482516838566e-16 -11.0658491341961 37.0282104839556 -0.298849147435601 0.765285034083668 TMEM135 other 9.76932503418002e-15 1 1.0638268493975e-11 8.58736311496956 -0.298849147435601 0.311547086217894 12.1051498107201 8.6281199874289 1.402988116572 0.161765028792925 17.6890889830508 18.2263762152901 0.970521445080863 0.332652044946802 IQCD other 1 1 1 1.402988116572 0.970521445080863 5.70135082489206e-14 259.60256892092 36.7628557391451 7.06154523911196 1.36640093994456e-11 -215.317099794398 110.437390411985 -1.94967573021385 0.0522384764252481 NDEL1 other 7.32452540473883e-10 1 1.87265248819402e-07 7.06154523911196 -1.94967573021385 8.57165234383773e-08 185.599296109634 35.5833909039657 5.21589683823386 3.62045612865119e-07 -37.4268779894172 91.72057802269 -0.408053228580379 0.683554439398398 CENPV other 0.000823992939813121 1 0.00413600908137112 5.21589683823386 -0.408053228580379 0.556151403498084 -103.333985326775 109.565138551321 -0.943128322503537 0.346458401749649 -13.9241931159607 190.813585607458 -0.0729727554337012 0.941881826402866 RRAD other 1 1 1 -0.943128322503537 -0.0729727554337012 5.86347713106483e-14 399.79044284406 65.9120121277748 6.0655171938772 4.42424231806281e-09 -154.597200418851 114.789316519797 -1.34679084348575 0.17917697134729 FAM96B essential 7.52987733171345e-10 1 5.57543016922275e-05 6.0655171938772 -1.34679084348575 0.915281499222148 1.49466901608251 9.77452366581165 0.152914767735477 0.87857886493412 -9.41175504352904 29.5482512037713 -0.318521559148238 0.750333782086091 CFAP52 other 1 1 1 0.152914767735477 -0.318521559148238 2.98597618696128e-08 599.995682271131 121.830105700081 4.92485563254937 1.47559184259754e-06 -974.76479699639 449.078026916833 -2.17059116360844 0.0308368824491097 BLCAP other 0.000295850520604124 1 0.0161680598193413 4.92485563254937 -2.17059116360844 0.19595474223968 -88.0229786559504 59.6738156240018 -1.47506871708311 0.141350626000665 -172.90438896946 105.679990599406 -1.63611283449937 0.102972520990218 SERPINB12 other 1 1 1 -1.47506871708311 -1.63611283449937 0.0127438923484328 25.9369489113952 11.564029933304 2.24289880439496 0.0257147600863083 -10.1795447814319 21.3629757802473 -0.476504064140921 0.634100700681278 CHRFAM7A other 1 1 1 2.24289880439496 -0.476504064140921 0.0195892601764333 -7.51145009555967 18.5818985551183 -0.404234802664483 0.686362463272007 -95.0895636343605 36.1970165745908 -2.62700003019339 0.00911018043977133 ATF7IP2 other 1 1 1 -0.404234802664483 -2.62700003019339 0.33859751193196 -165.856798546207 730.353526167176 -0.227091117662712 0.820524105768164 -2307.36299512751 1597.42035182862 -1.44443069883654 0.149773025413981 MMP10 other 1 1 1 -0.227091117662712 -1.44443069883654 3.86838988702026e-06 30.112861087293 9.67188396755446 3.11344317077317 0.00204876262550003 -37.7486366403189 18.7943829178902 -2.00850630772167 0.0455888676673288 TVP23A other 0.0328000778520448 1 1 3.11344317077317 -2.00850630772167 0.116767224472569 18.2099727390254 8.80646882250669 2.06779506134016 0.0396013115975738 20.2133466359395 15.5674201694836 1.29843907441794 0.195232268613859 TMPRSS5 other 1 1 1 2.06779506134016 1.29843907441794 4.61612977150676e-13 205.588651084719 28.4771985986221 7.21941276536474 5.23102276289317e-12 -78.9712507989797 62.6166757831236 -1.26118561567371 0.208322592955647 COG1 essential 5.75631382506893e-09 1 7.24548962888333e-08 7.21941276536474 -1.26118561567371 0.000462591454271017 -35.2946235502263 53.2603790902788 -0.662680667187898 0.508096231774672 -363.707080138916 100.305237854424 -3.62600286803344 0.000343572052992084 PLEKHA7 other 1 1 1 -0.662680667187898 -3.62600286803344 0.000523943687996673 30.1175012009381 12.547815116583 2.40021875690018 0.0170651660203684 -59.8722272457541 30.4526473941071 -1.9660762649273 0.0503180778766589 ZNF606 other 1 1 1 2.40021875690018 -1.9660762649273 0.929786736201926 915.830950138002 5240.34468851066 0.17476540276939 0.861393990108183 -2016.9884304666 9393.65727434863 -0.214718120063249 0.830147986886149 B2M other 1 1 1 0.17476540276939 -0.214718120063249 1.87420720506754e-08 279.749565083601 52.1543956742535 5.36387319739766 1.77593640974791e-07 -132.767802723669 103.816284371207 -1.27887261163136 0.202060697594371 ZNF592 other 0.000187814304019818 1 0.00206878832371534 5.36387319739766 -1.27887261163136 6.63343815224612e-05 180.959743431215 87.3164035986156 2.07245988122768 0.0391645644505332 -389.195933786036 156.520308985096 -2.4865522966933 0.0134990097324531 CASC4 other 0.501819596217419 1 1 2.07245988122768 -2.4865522966933 0.453659017570809 -10.3246585352145 26.2613793664341 -0.393149894799923 0.694515608942262 -56.7048058006855 46.4229119602015 -1.22148317299222 0.222956889512074 HTR3A other 1 1 1 -0.393149894799923 -1.22148317299222 0.533100394135824 -298.140843465634 273.483046542002 -1.09016206757754 0.276606588627348 -387.50146190925 480.099088489436 -0.807128093345206 0.420297900316217 NNMT other 1 1 1 -1.09016206757754 -0.807128093345206 5.57565698837217e-22 356.724439036611 73.2491545528721 4.87001442151968 1.9027083746921e-06 -688.399391277822 125.295964835786 -5.49418644231715 9.07320843832942e-08 AP1G1 other 8.34452824879779e-18 0.00143429278993111 0.020695758991526 4.87001442151968 -5.49418644231715 0.00318840188429674 326.162782392068 117.856150754442 2.76746508607464 0.00603715638751974 -111.438948927575 230.174173094451 -0.484150534481759 0.628668626055613 SLFN5 other 1 1 1 2.76746508607464 -0.484150534481759 0.00560687517258648 9.12850523333101 9.69496908460679 0.941571360740574 0.347253805223139 -39.5084524628825 17.4899535443832 -2.25892266452419 0.0246860717532326 CATSPER2 other 1 1 1 0.941571360740574 -2.25892266452419 0.290220463846053 13.8175914913551 19.5239470398649 0.707725311031716 0.479719607789007 -44.5341178102564 44.5370259438365 -0.999934703013536 0.318227578512708 ZNF667-AS1 other 1 1 1 0.707725311031716 -0.999934703013536 0.0600893737083017 56.5101372236057 33.5037273603212 1.6866821000499 0.0928237993886609 -38.9680924556705 67.778938610935 -0.57492922217852 0.565819701176278 C16orf45 other 1 1 1 1.6866821000499 -0.57492922217852 2.83128674144017e-19 119.838392393717 16.9625026470737 7.06490043875637 1.34814837970128e-11 -65.4924254846291 32.3731772940589 -2.02304595837889 0.0440465051376847 SAAL1 other 4.0954562714932e-15 1 1.84817661373248e-07 7.06490043875637 -2.02304595837889 0.0348094804497973 7.96286702622037 3.10558904825639 2.56404401950447 0.0108856270079148 3.78339234988414 8.0727807968557 0.468660359433734 0.639689185769983 YPEL4 other 1 1 1 2.56404401950447 0.468660359433734 1.12196042579855e-08 2135.22765822371 432.245559868914 4.93984867969784 1.36456873835171e-06 -1318.53084070507 856.508574654431 -1.53942514963969 0.124858783477964 PPIB other 0.000113935081239843 1 0.0149911521595318 4.93984867969784 -1.53942514963969 0.00560723223697854 3.55845073287642 2.94913794738251 1.20660708192192 0.228631864395633 -10.4195130430923 5.62847167199831 -1.85121532989665 0.0652224698505249 LDHC other 1 1 1 1.20660708192192 -1.85121532989665 7.19234047664499e-10 233.159801696525 42.2563459935905 5.51774641687882 7.97544316921176e-08 -116.59459358716 83.8332496848941 -1.39079176848573 0.165421157460151 FAM96A other 7.83533571525705e-06 1 0.000947562402934049 5.51774641687882 -1.39079176848573 0.000177603297877855 136.282411796745 53.1527768303838 2.56397539175867 0.010885723397593 -267.274960159763 126.534233400206 -2.11227391179127 0.0355744849505961 FAM111A other 1 1 1 2.56397539175867 -2.11227391179127 5.82795858285251e-11 243.218743456724 40.1025836209205 6.06491456400439 4.38476799087387e-09 -85.3608914431973 79.4645681207955 -1.07420065900866 0.283681277830839 PCLAF other 6.70215237028038e-07 1 5.52656157569743e-05 6.06491456400439 -1.07420065900866 0.000197506598616426 104.100955766379 27.6041786727311 3.77120279507593 0.000199341307010629 -33.0659472916031 58.8734834190287 -0.561644145569883 0.574820967210997 KIF7 other 1 1 1 3.77120279507593 -0.561644145569883 9.24089019986672e-05 16.9405291707779 25.3108162428838 0.669299994445687 0.503876036594122 -135.312282736737 42.9830236131186 -3.14804011822564 0.00182803617514254 LDHD other 0.687984275380077 1 1 0.669299994445687 -3.14804011822564 0.000135857571605701 36.045637256056 11.460732770326 3.14514245977228 0.00184418112740783 -43.55080525083 24.4431565497091 -1.78171772382435 0.0759109009520278 PEX11A other 0.989994124290745 1 1 3.14514245977228 -1.78171772382435 1.19414486364797e-17 117.992684991541 20.2278138156101 5.83319018392804 1.55125233862264e-08 -93.8223421438375 34.3071308248034 -2.73477670350695 0.00665546073227101 TMEM170A other 1.68075889558452e-13 1 0.000190881600267516 5.83319018392804 -2.73477670350695 0.150669335054786 5.92163480778737 6.35021648941051 0.932509122746 0.351900466071285 -18.08738509028 13.5435786599176 -1.33549525900491 0.182830780844942 MESP1 other 1 1 1 0.932509122746 -1.33549525900491 0.411930393531169 -69.8962134231034 54.3147607766042 -1.28687326287941 0.199232559090876 -85.4892579274467 115.841127022873 -0.737987104619303 0.461158499757893 ANPEP other 1 1 1 -1.28687326287941 -0.737987104619303 0.112976402483578 83.9031558683984 60.1632605537444 1.39459123551735 0.164277061113664 -75.9135083824166 113.294152327335 -0.670056722460692 0.503390086902201 SCNN1G other 1 1 1 1.39459123551735 -0.670056722460692 0.0731197310366207 18.9854855147366 8.68491349942965 2.18603046719848 0.0296659091844592 3.93024438376356 17.1102898805593 0.229700631093872 0.818497043162714 RBPMS2 other 1 1 1 2.18603046719848 0.229700631093872 5.6454922693532e-06 649.534334665564 183.177069203338 3.54593693135542 0.000460224506565468 -401.288568436479 356.488434488559 -1.12567065187456 0.261293566984462 NAV2 other 0.0471963153717928 1 1 3.54593693135542 -1.12567065187456 0.113932839734667 11.5033444699901 9.37645754935071 1.22683267208805 0.220950271107214 -19.7942682105175 18.5017623211087 -1.06985852844591 0.285634953981985 ANKDD1A other 1 1 1 1.22683267208805 -1.06985852844591 3.84777395339948e-13 84.8339010023967 13.7276195430047 6.17979692230225 2.37760020902302e-09 -20.8002581196083 22.836327448966 -0.910840771840052 0.363197779441349 C18orf54 other 4.81164132872606e-09 1 3.02787386619082e-05 6.17979692230225 -0.910840771840052 1.43320917690016e-27 755.149576860683 73.9900953409545 10.2060900635534 6.44265730244512e-21 -273.095000057232 154.920937801705 -1.76280239412691 0.0790567962393037 DCTN5 essential 2.2236240379606e-23 1 9.9017200081279e-17 10.2060900635534 -1.76280239412691 8.55434893849783e-15 497.653776343669 66.1933055591158 7.5181889186547 8.08166357911622e-13 -25.7644429090568 138.595969178822 -0.185896047783427 0.852664837920854 PLK1 essential 1.12378482005046e-10 1 1.14064599755646e-08 7.5181889186547 -0.185896047783427 6.45144363329244e-18 276.196423796095 35.4056499567428 7.80091381272595 1.33515559692201e-13 -141.472089477596 69.8629431079106 -2.02499469939418 0.0438482313773277 CLPX other 9.12943788547213e-14 1 1.91180929923262e-09 7.80091381272595 -2.02499469939418 6.24242914761036e-12 132.921148866579 20.1711747370096 6.58965829207251 2.26367462410596e-10 -67.8146521373735 54.0220191715458 -1.25531502112184 0.21043785829294 ZBTB39 other 7.45595737390581e-08 1 2.99054054590639e-06 6.58965829207251 -1.25531502112184 0.627237849585737 -57.3524848952893 70.1009158820529 -0.818141734293269 0.413989778318026 -142.276805183301 187.742809781668 -0.757828251045989 0.449207460252618 TAC3 other 1 1 1 -0.818141734293269 -0.757828251045989 0.0299121630850691 72.8315726878414 28.976791919186 2.51344499732624 0.0125340759591707 117.664432629076 60.8024888810272 1.93519105540746 0.0540033781013636 CHP2 other 1 1 1 2.51344499732624 1.93519105540746 2.21734302672356e-10 373.629162313179 61.9394084856956 6.03217194751651 5.24508263267919e-09 -206.496033593786 165.884831018251 -1.24481564906358 0.214267047652559 NEMP1 other 2.48187204981168e-06 1 6.59306886927775e-05 6.03217194751651 -1.24481564906358 1.55641294615297e-05 274.365329577977 69.906946459075 3.92472198365289 0.000109972938824306 -244.069839413074 187.223324921543 -1.3036294463596 0.193458198529035 NAB2 other 0.125400191071545 1 1 3.92472198365289 -1.3036294463596 5.64427025829208e-12 292.250453019596 62.8450011714978 4.65033729925588 5.16806958950395e-06 -312.200892586693 109.696997033938 -2.84602952704444 0.00476252556698904 VPS39 other 6.75280493702064e-08 1 0.054300907176918 4.65033729925588 -2.84602952704444 0.000240224621300629 284.959603416163 183.439101224278 1.55342891190773 0.121479181591256 -1526.6707428565 491.282772191095 -3.10751939468104 0.00208575393140307 STAT6 other 1 1 1 1.55342891190773 -3.10751939468104 1.47460489568194e-08 346.867469522436 67.8411089154318 5.11293926452216 6.01653048542557e-07 -213.141833461764 156.054807904429 -1.36581394911137 0.173134000204545 PATL1 other 0.000148536951142042 1 0.00677100340829794 5.11293926452216 -1.36581394911137 0.0490061889991109 18.0062860008071 10.3995301786319 1.73145187248987 0.0845050637101429 -28.8792604776871 26.9574458172223 -1.07129068063403 0.28498838352872 ATP23 other 1 1 1 1.73145187248987 -1.07129068063403 0.309735410210471 12.9932505222501 8.47451387539754 1.53321485023123 0.126380947014784 12.3408538212732 20.0162939575667 0.61654039691039 0.538051698652793 ELFN2 other 1 1 1 1.53321485023123 0.61654039691039 1.29436244650215e-05 174.434767145483 57.0996576643735 3.05491791510896 0.00247642425754236 -308.645628750007 131.346262622714 -2.34986228452177 0.0195006768443353 STX3 other 0.104972794411324 1 1 3.05491791510896 -2.34986228452177 2.60284897088005e-10 144.881014008812 27.1573123806027 5.3348804174118 2.02511973854987e-07 -131.590128628164 62.469927666402 -2.10645559461623 0.0360876440375056 MRPL16 essential 2.90269717232544e-06 1 0.00235166554488593 5.3348804174118 -2.10645559461623 7.50537453711403e-11 234.667968927452 52.715778873155 4.45156979454125 1.24339715941989e-05 -532.398429337211 141.182298703875 -3.77099986489028 0.000199350813704397 PIP4K2C other 8.58764954536588e-07 1 0.126714604516481 4.45156979454125 -3.77099986489028 1.26613730792845e-08 154.761054907409 45.2540396218086 3.41982851035529 0.000723489747510594 -216.519861560908 83.5656209907589 -2.59101600626952 0.0100895509201967 MTMR10 other 0.000128158418308518 1 1 3.41982851035529 -2.59101600626952 6.99045520423806e-23 1566.39746411305 167.689948125053 9.34103374487855 3.57565723717471e-18 -1880.09168428558 573.038334278489 -3.2809178231554 0.00116973191325512 YWHAB other 1.0541606447991e-18 1 5.40996939984534e-14 9.34103374487855 -3.2809178231554 0.709884088083804 -58.9309868161214 167.666816407147 -0.351476744647066 0.725505861488728 -252.026963946511 306.771867294826 -0.821545228931631 0.412063299956046 SCG5 other 1 1 1 -0.351476744647066 -0.821545228931631 0.0904286542588676 -271.556779071298 189.864452106103 -1.43026657206765 0.15380102148747 224.130890899174 347.385808078212 0.645192997777019 0.519352021848326 GREM1 other 1 1 1 -1.43026657206765 0.645192997777019 0.000127226818755488 19.4199494447442 4.51857383020472 4.29780505409256 2.40488948416885e-05 14.5514044704479 19.6717331397281 0.739711359801875 0.460113092413199 NYAP1 other 0.930536952377641 1 0.239334601464484 4.29780505409256 0.739711359801875 9.62828427480637e-18 247.818247805984 30.3934815667722 8.15366437245913 1.30587274691788e-14 -400.899200963852 134.161389520969 -2.9881861122286 0.00306270883829194 TSC22D4 other 1.35797321411869e-13 1 1.89978367221613e-10 8.15366437245913 -2.9881861122286 0.20016060763696 -0.399001225038992 2.08291719140707 -0.191558851540064 0.848230173068755 -8.55633840530717 4.91425402384961 -1.74112660106335 0.0827879236409513 MS4A6E other 1 1 1 -0.191558851540064 -1.74112660106335 0.479775678080323 -76.1499099629813 99.8208384497476 -0.762865861934401 0.44620206679791 -271.413925948736 235.508621773071 -1.15245855504289 0.250140836081653 MS4A7 other 1 1 1 -0.762865861934401 -1.15245855504289 0.474915944534535 -8.40188642616632 8.62992256637287 -0.973576108191849 0.331128898456892 -21.0691946205392 20.3606902243961 -1.03479766099944 0.30167917806982 MS4A14 other 1 1 1 -0.973576108191849 -1.03479766099944 1.05836153823081e-10 182.338045405424 30.6810526807818 5.94301790432496 8.57755236003564e-09 -67.3998796899798 61.684791689067 -1.09264987113389 0.275517922383441 DIS3L other 1.20198119896873e-06 1 0.000106833414644244 5.94301790432496 -1.09264987113389 5.22188392793956e-05 71.2489180587824 51.7611566781195 1.37649393157593 0.169800805142274 -283.328258212292 91.7562661962363 -3.08783552293145 0.00222468220741712 CCNDBP1 other 0.399265245130259 1 1 1.37649393157593 -3.08783552293145 0.118629987434341 -1.79727780286096 2.6655587897154 -0.674259299699354 0.500719104131049 -9.63913048266141 4.72519815180701 -2.03994206655126 0.0423220798709501 EPB42 other 1 1 1 -0.674259299699354 -2.03994206655126 0.0465367090044423 -109.693641042671 187.611059111504 -0.584686433529891 0.559246826963505 -878.96305177977 359.3123648871 -2.4462365831912 0.0150740404540751 SMAD3 ts 1 1 1 -0.584686433529891 -2.4462365831912 0.714611455452407 -48.0666894219864 107.942815300125 -0.445297718874032 0.656457503553614 -196.736299072495 246.071718843109 -0.799507964578128 0.424691014061399 MS4A8 other 1 1 1 -0.445297718874032 -0.799507964578128 0.937363984403703 12.2437686375422 75.2962926765417 0.162607854946313 0.870947497048609 -38.4527888608257 159.553880421588 -0.241001903302021 0.809734540460558 MS4A15 other 1 1 1 0.162607854946313 -0.241001903302021 0.4143741672311 75.7045260146771 91.9410780391763 0.823402636005847 0.411000412464021 -83.444240218105 164.510567030339 -0.507227236063909 0.61240637430006 MAP1A other 1 1 1 0.823402636005847 -0.507227236063909 8.26708493035549e-10 163.314288900408 25.0201852253969 6.52730135405371 3.30038113613495e-10 29.634719664133 60.0897417605874 0.493174355486585 0.622290264953629 RCCD1 other 8.97729963243549e-06 1 4.33670081288132e-06 6.52730135405371 0.493174355486585 1.83346970150947e-08 76.9057319145414 32.824410328375 2.34294328961823 0.0198531547819267 -193.021795785628 58.8140521830375 -3.28189928462874 0.00116582427602508 AKTIP other 0.000183860341667369 1 1 2.34294328961823 -3.28189928462874 0.000117461961313363 148.244296957228 59.2426024255981 2.50232587508973 0.0129409889999582 -226.79229972234 107.026582136144 -2.11902777044536 0.0350183769169772 MAPRE2 other 0.862640643885335 1 1 2.50232587508973 -2.11902777044536 0.0257417330532996 122.637218440811 53.0990913057758 2.3095916601396 0.0216683403578171 -7.72198390618629 76.0205138309611 -0.10157763368131 0.919167606043073 EVA1C other 1 1 1 2.3095916601396 -0.10157763368131 5.51054205988034e-06 166.964827601872 84.0184335765841 1.98724042444425 0.0478949601608901 -832.180430313907 225.016415187247 -3.69830987495472 0.000262369128795552 MBD6 other 0.0461122159570787 1 1 1.98724042444425 -3.69830987495472 4.14714926594131e-05 39.6747167762783 9.33291653495679 4.25105235085679 2.92724280771029e-05 -28.5800298251979 41.1509311003146 -0.69451720923465 0.487950704827482 CNPY4 other 0.320242866315988 1 0.289298595984967 4.25105235085679 -0.69451720923465 3.61143670249397e-06 1757.47117375017 542.750585634411 3.23808250099978 0.0013537666264685 -1852.25745343356 979.134894200402 -1.8917285701948 0.0595972130405528 PDIA3 other 0.0306755433509838 1 1 3.23808250099978 -1.8917285701948 6.01928482130538e-20 514.254075615681 106.012964303922 4.85086026027341 2.06836364061172e-06 -832.041300535705 190.214446541521 -4.37422769754809 1.73556357789923e-05 NUDT21 essential 8.79116548151651e-16 0.265575938690141 0.0224210618642311 4.85086026027341 -4.37422769754809 4.24109443739137e-05 -12.1968611236671 22.1168284897318 -0.55147423733605 0.581761369371754 -145.604850789262 37.32248257242 -3.90126381616583 0.000120668210129475 NKX3-1 other 0.327200435844744 1 1 -0.55147423733605 -3.90126381616583 0.629447254408689 5.25691699178816 11.3311158195984 0.46393639209792 0.643065754044194 31.2066883516086 32.8032551865586 0.951329012140105 0.342285062527201 SGSM1 other 1 1 1 0.46393639209792 0.951329012140105 8.45625501665968e-08 25.8055074914114 6.91610428052245 3.73122012692702 0.000231971055218476 -69.8991329409437 21.9487559930264 -3.18465123778096 0.001617902955041 DUSP18 other 0.000813407170052495 1 1 3.73122012692702 -3.18465123778096 7.8559944494395e-07 132.754215978353 42.4382973603367 3.12817017259572 0.00195154197581041 -296.740723676247 100.178974989219 -2.96210580821157 0.00332749315502312 TEF other 0.00705389741615172 1 1 3.12817017259572 -2.96210580821157 0.012779479094705 -37.0823854296799 12.616856366071 -2.93911449522411 0.00357615804040867 -44.8328989668273 29.1845302212848 -1.53618710415732 0.125663494873999 MEI1 other 1 1 1 -2.93911449522411 -1.53618710415732 0.339640266115237 64.6055622854447 45.3088373937823 1.42589318114595 0.155050043525351 81.2875605206226 99.821294484617 0.814330859365378 0.41617042349562 B4GALNT2 other 1 1 1 1.42589318114595 0.814330859365378 0.000947567814685276 46.698549601279 33.4189540723313 1.39736717972099 0.163437785138075 -168.472121271872 64.275669959035 -2.62108697395523 0.00925633735716363 PBX3 other 1 1 1 1.39736717972099 -2.62108697395523 0.301237105282038 -4.87712426901153 3.20026371394463 -1.52397574229906 0.12868085715664 -5.4932445246011 7.05059950759054 -0.779117367067464 0.436590397189453 GNGT2 other 1 1 1 -1.52397574229906 -0.779117367067464 8.57029292654642e-17 961.875211801986 108.213971478157 8.88864162975607 8.86633964371742e-17 114.771375432783 240.752182930057 0.476719978344398 0.633945700186159 PHB essential 1.18505777815219e-12 1 1.32480846956426e-12 8.88864162975607 0.476719978344398 4.66804457715877e-16 514.388314958318 61.585810064858 8.35238368086087 6.5324544788644e-15 -19.4327614205074 135.878837118164 -0.143015364516317 0.886404356540068 SNRPD1 essential 6.34013814469704e-12 1 9.54522248451666e-11 8.35238368086087 -0.143015364516317 0.66148863925407 -2.63935076101887 3.65606780219681 -0.721909686530694 0.470970145271794 -5.43888584903203 6.7756180216706 -0.802714354858365 0.422840680026197 TTC16 other 1 1 1 -0.721909686530694 -0.802714354858365 0.000479077264605516 46.0068137879466 14.8553034478157 3.09699589439969 0.00216170536046847 -43.5921467539687 33.3959190737905 -1.30531358210711 0.192901452971803 SAMD14 other 1 1 1 3.09699589439969 -1.30531358210711 0.000253790590730774 19.575183775514 5.22678517731543 3.7451670790817 0.000220055223204564 -0.245626702488928 9.73037054013595 -0.0252433040936893 0.979879405791505 PIP5KL1 other 1 1 1 3.7451670790817 -0.0252433040936893 0.838846174217249 -3.19470817674665 10.827078483564 -0.295066502159042 0.768169840215909 -14.1328736169945 24.2478727191121 -0.582850041350433 0.560480714253305 TMEM92 other 1 1 1 -0.295066502159042 -0.582850041350433 4.52780954073962e-18 951.885969625732 192.814472427342 4.9367973142391 1.38697839610711e-06 -1961.03557222285 358.950329613985 -5.46325051249219 1.0559035238988e-07 FAM102A other 6.42269783353916e-14 0.00166811638705533 0.0152263389382595 4.9367973142391 -5.46325051249219 0.498861499291046 52.9221979043597 44.8290433326214 1.18053373371564 0.238819320844498 40.8134396002399 99.0016888469059 0.412249933062788 0.680480958155994 ACSF2 other 1 1 1 1.18053373371564 0.412249933062788 1.94163928489704e-06 321.771775066235 88.1734386472625 3.6493050515301 0.000315190683013367 -314.526489794395 164.146832274532 -1.91612890383626 0.0563967561334273 GOLGA2 other 0.016896145057174 1 1 3.6493050515301 -1.91612890383626 5.48505531353114e-29 302.172763909101 34.5313759257066 8.75067256396669 2.2756708087695e-16 -320.862856823016 64.2848465393469 -4.99126736853335 1.07238192712914e-06 TRUB2 other 8.55997732229669e-25 0.0167859943053525 3.3873359988534e-12 8.75067256396669 -4.99126736853335 3.7989904930081e-14 166.877200641815 33.2676655860172 5.01619809211848 9.52583187778869e-07 -244.870304862122 61.9322780974782 -3.9538397808766 9.81309839296899e-05 COQ4 essential 4.90677612076926e-10 1 0.0105793888834721 5.01619809211848 -3.9538397808766 4.21054500507527e-07 103.81787193552 53.3705919649855 1.94522616506917 0.0527780368132066 -390.622502705325 99.3566060490821 -3.93152019013569 0.000107161515764513 SLC27A4 other 0.00386864875066316 1 1 1.94522616506917 -3.93152019013569 5.68084200370775e-26 290.540994066943 38.1357105814852 7.61860706505361 4.26852989933755e-13 -376.505515131162 70.9948050629134 -5.30328261057291 2.35777204021605e-07 URM1 essential 8.75020093831104e-22 0.00371608451258452 6.06643469293852e-09 7.61860706505361 -5.30328261057291 0.162041905280521 203.398432777343 109.792475211696 1.8525717029802 0.0650269699501679 247.377764095677 204.393605263341 1.21030089848924 0.227214150893505 CERCAM other 1 1 1 1.8525717029802 1.21030089848924 1.71277311195695e-26 184.300519395742 23.8480664290222 7.72811162465797 2.13578751489282e-13 -239.855886705193 44.4442544753512 -5.39678051835062 1.48148818231652e-07 DOLPP1 other 2.64332274368317e-22 0.00233852909578663 3.05161320127886e-09 7.72811162465797 -5.39678051835062 9.82805596680986e-05 28.8681675577748 7.23916651032976 3.98777504517709 8.56963174434578e-05 -2.54014687326623 15.1429046576799 -0.167745021889044 0.86690807081164 CCDC103 other 0.729438313856628 1 0.808887540348799 3.98777504517709 -0.167745021889044 2.11715639216511e-17 129.833989574352 20.0228785265849 6.4842819378826 4.20468991740076e-10 -132.046677697302 37.3154742424571 -3.53865736341255 0.000473071544116375 ENDOG other 2.96804154617627e-13 1 5.50688238481978e-06 6.4842819378826 -3.53865736341255 0.118116438289309 22.7753670548325 20.8251919369567 1.09364500090945 0.275078292217882 -46.2169157502079 39.8383594194022 -1.16011091881709 0.247020915407796 PRRX2 other 1 1 1 1.09364500090945 -1.16011091881709 0.0239362909933101 1903.28873829472 692.348205197924 2.7490339745311 0.00637889121657447 1667.04749466075 1061.17046422946 1.57095165277827 0.117360672205986 UGT1A6 other 1 1 1 2.7490339745311 1.57095165277827 1.90006797816318e-05 190.192202894849 64.8128417978206 2.93448331563891 0.0036315551815267 -293.00161146997 126.138223730555 -2.32286140397738 0.0209384068627356 C15orf39 other 0.152005438253055 1 1 2.93448331563891 -2.32286140397738 0.520789290401418 -14.1177799607073 12.9496865112786 -1.09020244995208 0.27659597588561 -18.528325494632 24.358270736227 -0.760658492356585 0.447524833106212 ISLR2 other 1 1 1 -1.09020244995208 -0.760658492356585 2.08144203604106e-06 88.0674040244108 18.5564122606509 4.74592840401367 3.36943550565989e-06 -19.5494956584966 39.2394357113961 -0.498210417761408 0.618741314218139 SP2 other 0.0180565096626562 1 0.0359350296678627 4.74592840401367 -0.498210417761408 0.452471801287158 1.85197322056864 30.6932543940592 0.0603381184931336 0.951930979888188 -75.6793451429354 64.9040323987157 -1.16601915699205 0.244635651729753 PRR15L other 1 1 1 0.0603381184931336 -1.16601915699205 5.46931990272589e-21 124.123933656333 17.218797388502 7.20862966534571 5.63297168453927e-12 -98.6971955533092 33.66751509273 -2.93152599119563 0.00366080302272655 COQ7 other 8.09568732001486e-17 1 7.79321632556008e-08 7.20862966534571 -2.93152599119563 0.0170457135027228 252.930356102995 121.175027687929 2.08731420102817 0.0377974086022752 -156.498831444485 241.183135881109 -0.648879660979409 0.516967693251575 GPRC5B other 1 1 1 2.08731420102817 -0.648879660979409 1.53057955824863e-22 496.191864927091 51.1128996504924 9.70776199980879 2.58604074870565e-19 -400.069828866452 158.310385846819 -2.5271230736154 0.0120693715486455 CRK other 2.30168553969428e-18 1 3.94319493362638e-15 9.70776199980879 -2.5271230736154 1.02358720730547e-15 222.954325767262 29.1653763723437 7.64448649387841 3.75549400979973e-13 -63.8428425656496 56.7250943501091 -1.12547794405787 0.261393454174224 FBXO22 other 1.37815781591608e-11 1 5.34369242654404e-09 7.64448649387841 -1.12547794405787 0.412123578035257 57.9890013496147 62.7414389826774 0.924253607980288 0.356173499977859 -68.9577207246026 121.342407151488 -0.568290363965774 0.570306670166755 TBC1D2B other 1 1 1 0.924253607980288 -0.568290363965774 0.00895461251651742 -22.6406672678087 19.7274570455046 -1.14767287114524 0.252130917453927 -106.510189359783 35.3010037676093 -3.01720002243995 0.00279751236576148 NOD2 other 1 1 1 -1.14767287114524 -3.01720002243995 0.0457645911296263 -49.7355099689409 19.9123240857989 -2.49772501465117 0.0131015496133687 -49.7050846608556 35.6318113355021 -1.39496373599541 0.164186103712762 SNX20 other 1 1 1 -2.49772501465117 -1.39496373599541 8.29397513469864e-07 41.7421084666545 8.26673064217897 5.04940952759191 8.1466900586621e-07 4.26930176868095 14.236559716382 0.29988296707443 0.764496315692194 KATNAL2 other 0.00742891352814958 1 0.00908844742944344 5.04940952759191 0.29988296707443 8.32154557428357e-25 188.874612478909 22.1255667701418 8.53648697188598 1.00434434969838e-15 -141.610454457879 38.3856907284794 -3.68914696519489 0.000271896063741874 HDHD2 other 1.27236431830796e-20 1 1.48261312902474e-11 8.53648697188598 -3.68914696519489 0.181577526683282 3.51238485611615 30.8747861250183 0.113762240874926 0.909513065172439 -98.6301667400039 63.6398154783315 -1.5498185530344 0.122387548147557 ZNF91 other 1 1 1 0.113762240874926 -1.5498185530344 0.392096402152305 -1199.21644530089 3337.02805031186 -0.359366606219811 0.719598657744505 3642.35287840648 4920.00687647893 0.740314590985527 0.459745334154228 IGF2 other 1 1 1 -0.359366606219811 0.740314590985527 1.90702331080824e-19 130.276351107476 18.5910533859201 7.00747549927109 1.89722996583411e-11 -84.2078748140475 33.2858010593322 -2.52984372116946 0.0119741872549402 RNF214 other 2.76556520533411e-15 1 2.59066751834648e-07 7.00747549927109 -2.52984372116946 8.87973839423331e-14 383.488307172796 59.8041423256331 6.41240376100882 6.53947155135036e-10 -195.604253129942 115.912516910051 -1.68751622641179 0.0926807221734158 CDK12 other 1.13403139032754e-09 1 8.50392880537601e-06 6.41240376100882 -1.68751622641179 0.452634861451408 -15.1784304661664 13.9896767097469 -1.08497364028372 0.278904727095802 -28.242932830779 25.0615450110072 -1.12694300444663 0.260770845261835 DPEP2 other 1 1 1 -1.08497364028372 -1.12694300444663 2.25590647296255e-23 95.0859016147323 12.8812829658711 7.38171049162274 1.95573654529811e-12 -73.7395571833257 23.0759337436141 -3.19551780667303 0.00156222909403945 DUS2 other 3.41657035330179e-19 1 2.73685772149017e-08 7.38171049162274 -3.19551780667303 2.8623275492389e-07 129.887983193919 25.7486016845694 5.04446745439222 8.34148713849364e-07 -43.3873047704549 53.7277978793716 -0.807539234492117 0.420064102005805 POP5 essential 0.00266110592252741 1 0.0092990898619927 5.04446745439222 -0.807539234492117 0.0199239182629838 98.8267941513929 42.0119023983362 2.35235227422852 0.0193653484841104 -76.7900503074345 94.2935481211981 -0.814372264460068 0.41614151739435 ENGASE other 1 1 1 2.35235227422852 -0.814372264460068 0.169204389665388 4.23423416002276 4.26623566456266 0.99249888964041 0.321833085279619 -12.048052915968 9.57534591313203 -1.25823683293204 0.209381163969352 RBFOX3 other 1 1 1 0.99249888964041 -1.25823683293204 1.29267524303226e-11 776.139681158269 152.177700701721 5.10021953005821 6.4113759095722e-07 -543.533790516881 269.801252951293 -2.01457103913081 0.0449446828570539 ATP5L other 1.52768360221552e-07 1 0.00720125742163149 5.10021953005821 -2.01457103913081 0.154301624468242 -20.172831203766 17.3190747263631 -1.16477534293786 0.245141840627081 22.5431517596951 30.7056029863973 0.73417062578715 0.46348419916995 CD3D other 1 1 1 -1.16477534293786 0.73417062578715 0.000413865315927315 238.195141013964 69.8022635819033 3.4124271734322 0.000742199746270954 -159.722207690296 157.001531925037 -1.01732897591444 0.309904325460896 TBC1D16 other 1 1 1 3.4124271734322 -1.01732897591444 2.46976410793465e-07 140.612098923245 26.7162024712249 5.2631768708406 2.90438222704254e-07 -13.0024130914648 59.2599649538026 -0.219413108016535 0.826495278099159 TEPSIN other 0.00230552479475699 1 0.00333945868465351 5.2631768708406 -0.219413108016535 4.12344048038223e-13 406.01602527283 115.934605225101 3.50211245800595 0.000540285436327291 -803.506701129621 183.978941236797 -4.36738409150554 1.79610210615158e-05 MYO5B other 5.15265122428564e-09 0.274713817135884 1 3.50211245800595 -4.36738409150554 0.000697881313481576 19.2865112343186 6.51177721904841 2.96178916838573 0.00332978076589217 -0.815827834339213 9.65305050909859 -0.0845150280287299 0.932709354645897 ART5 other 1 1 1 2.96178916838573 -0.0845150280287299 1.01310420026193e-05 201.374959007025 79.9411740784336 2.51903929768967 0.0123455286219497 -295.151372324101 126.486914519173 -2.33345380781947 0.0203586904372403 ACAA2 other 0.082922578791439 1 1 2.51903929768967 -2.33345380781947 1.0080906746688e-12 838.173429216313 184.511289695766 4.54266744651966 8.3699140778073e-06 -600.008374013612 276.207243506665 -2.17231223336521 0.0306990315157564 RRM1 essential 1.24227013839436e-08 1 0.086477952251905 4.54266744651966 -2.17231223336521 4.95545130264415e-15 94.5261328796199 22.0590630316036 4.28513816494354 2.53392887599247e-05 -108.275186707546 33.4605190190155 -3.23590876298165 0.00136200821527195 TRIM68 other 6.56151306983112e-11 1 0.251745833829852 4.28513816494354 -3.23590876298165 5.43196071570659e-05 56.9607459798119 18.8417315661161 3.02311630860121 0.00275190686383662 -83.0234777689501 41.048336517816 -2.0225783749584 0.0441403105537704 FN3K other 0.414567241822727 1 1 3.02311630860121 -2.0225783749584 0.140687887201271 -9.16934023367913 12.0388368925098 -0.761646686930694 0.446948190423071 -47.115006350206 23.882319811279 -1.97279856908853 0.0495578133204931 PRRT2 other 1 1 1 -0.761646686930694 -1.97279856908853 1.88643984280597e-12 50.7793896465879 10.4613162499681 4.85401534885656 2.04199472110105e-06 -43.6387927991087 18.0857480983547 -2.41288292647837 0.0164885635640676 ZNF23 other 2.30164525220757e-08 1 0.0221556427239464 4.85401534885656 -2.41288292647837 6.38423179161562e-14 174.005702114199 28.4148159135593 6.12376665200088 3.17206522063807e-09 -227.387532885684 78.2374626656414 -2.90637662749183 0.0039562335374281 IRGQ other 8.1884156959262e-10 1 4.02313031933526e-05 6.12376665200088 -2.90637662749183 9.57713387119613e-16 65.2837074076277 9.28003452344279 7.03485609269136 1.60704315057298e-11 -68.3935312423784 25.4922932566838 -2.68291010752617 0.00774383991663056 ZNF226 other 1.29090187449853e-11 1 2.19859573429889e-07 7.03485609269136 -2.68291010752617 2.29393848798445e-21 52.8778688443746 6.57830635003813 8.03821926658495 2.80415885488891e-14 -72.7908214384964 18.7209072308609 -3.8882101460608 0.000126980648139605 ZNF180 other 3.41016895623769e-17 1 4.05845911068071e-10 8.03821926658495 -3.8882101460608 6.01890293262283e-06 29.0503824519901 13.0824001118579 2.22056978869334 0.0272228291044767 -76.2590893847235 27.1606178442875 -2.80770819802108 0.00535902856406853 ZNF668 other 0.0501856126522091 1 1 2.22056978869334 -2.80770819802108 1.41016312673022e-13 185.679829379027 33.2646800923884 5.58189132928154 5.86065401446165e-08 -163.269216217536 68.6482075257426 -2.37834638517417 0.0180970026988028 ZNF646 other 1.78935599150797e-09 1 0.00070152028553106 5.58189132928154 -2.37834638517417 6.21005435654555e-06 329.040562146066 78.4394464248964 4.19483534296884 3.72375196852512e-05 -48.1323248226254 161.875219645139 -0.297342143708843 0.766437385856027 VKORC1 other 0.0516987025182417 1 0.364108467482386 4.19483534296884 -0.297342143708843 0.00346598688177611 10.9921041183726 3.36308714656994 3.26845652203323 0.0012198881682521 13.0321514799106 7.21273891807695 1.80682423527749 0.071890641269928 LPO other 1 1 1 3.26845652203323 1.80682423527749 0.603218165874294 -20.4890922278636 23.3747656983288 -0.87654749109757 0.381520419267911 -36.4059807430198 50.1698156097181 -0.725655063718587 0.468685814186529 CA4 other 1 1 1 -0.87654749109757 -0.725655063718587 1.43510299554022e-18 143.810466434871 16.2234215262372 8.86437341237141 1.04982493091638e-16 -52.6759116425968 34.7099089179663 -1.51760443299035 0.130279811218893 SMG8 other 2.05363238661806e-14 1 1.56738862185816e-12 8.86437341237141 -1.51760443299035 3.25829433206755e-08 1172.91901927665 467.145826167889 2.5108198630359 0.0126298238201597 -3992.44313073631 1055.02032472209 -3.78423338127443 0.000189961279445014 TPM4 other 0.00032172398234835 1 1 2.5108198630359 -3.78423338127443 8.37226074458458e-27 326.387263668009 44.3721454939089 7.35567910983284 2.24518107374058e-12 -541.294928673813 99.5166429461912 -5.43924023810261 1.19256655168034e-07 RAB8A other 1.29468640154256e-22 0.00188342035506877 3.13808958676721e-08 7.35567910983284 -5.43924023810261 9.85964770374245e-09 687.146969339876 222.994736188903 3.08144928029952 0.00227209348823896 -1125.30635263539 387.728941931633 -2.90230166215916 0.00400875498864167 GPX4 other 0.000100558546930469 1 1 3.08144928029952 -2.90230166215916 0.0798494292098963 71.6297126588896 149.219850517949 0.480028041914394 0.631596101974996 -411.386364018169 260.801409715065 -1.57739317616275 0.115875962319749 MIDN other 1 1 1 0.480028041914394 -1.57739317616275 0.501555574630305 -8.33562602168427 10.9331711919286 -0.762416125692609 0.446469906525569 -28.563853739695 25.0279353707105 -1.14127886765772 0.25475400569243 FAM129C other 1 1 1 -0.762416125692609 -1.14127886765772 1.91680574428521e-21 96.6677736975475 11.2593864034288 8.58552768631416 7.08774513190414e-16 -47.9299413735343 26.0425017518383 -1.84045073051214 0.0667913642329203 KLHL26 other 2.85124854462424e-17 1 1.04806487265467e-11 8.58552768631416 -1.84045073051214 3.20737055710914e-18 544.69200168305 74.9352479528429 7.26883564895691 3.91400234457902e-12 -432.497838809623 172.541715997893 -2.50662766571131 0.0127770565287119 GATAD2A other 4.56280535454347e-14 1 5.44085465919929e-08 7.26883564895691 -2.50662766571131 2.52661907733887e-09 388.641124233783 86.6647776662711 4.48441840732994 1.08364534110392e-05 -173.615034503147 142.545757584962 -1.21796002521974 0.224306388082346 MVD essential 2.66912039330078e-05 1 0.110986955835863 4.48441840732994 -1.21796002521974 8.1383851132398e-13 316.209876058109 53.436001025047 5.91754379055971 9.91466099197776e-09 -63.9919364797814 87.8912454810414 -0.728080892807291 0.467197358101849 CDT1 essential 1.00671823850776e-08 1 0.00012312026019838 5.91754379055971 -0.728080892807291 1.41871460020625e-13 216.862897335064 40.9282003383861 5.29861795881777 2.43139573945909e-07 -126.43678554415 67.5072914675601 -1.87293524588982 0.0621618270648976 TRAPPC2L other 1.79978134182165e-09 1 0.00280972091651893 5.29861795881777 -1.87293524588982 1.18793905422218e-10 450.86871963908 131.039126637451 3.44071828932826 0.000673498913697893 -657.502619797737 213.639848244912 -3.07762163846882 0.00230459524928895 ANKRD11 essential 1.34629133015e-06 1 1 3.44071828932826 -3.07762163846882 1.21423377098145e-12 53.1997242013326 10.4068245822387 5.11200354929866 6.14126339911534e-07 -31.0914893531236 16.9576400112253 -1.83347973730674 0.0678613410614693 SPATA33 other 1.49120049414232e-08 1 0.00690646481864511 5.11200354929866 -1.83347973730674 1.22435303507162e-08 26.5432878508015 4.43529408810385 5.98456096113102 7.22470165036921e-09 8.89372844214052 9.99209215023794 0.89007670349885 0.374253911283077 PROCA1 other 0.000124039205983106 1 9.02292989114611e-05 5.98456096113102 0.89007670349885 8.39923339882778e-10 3903.68214364472 913.733557597467 4.27223243711099 2.70378896032476e-05 -2605.82524681107 1486.81797335784 -1.75261887702774 0.0808282818143125 RPL13 essential 9.11652793108767e-06 1 0.267918448078581 4.27223243711099 -1.75261887702774 0.00479637225997413 -2.83139614822566 24.2877117589612 -0.116577311865577 0.907280729525748 -193.031742123623 61.3579521977157 -3.14599388033047 0.0018383179532941 ZNF641 other 1 1 1 -0.116577311865577 -3.14599388033047 0.0207766606020584 40.5820847155323 33.5874949721 1.20824981884605 0.228000590001015 -165.55438300511 83.7472932011487 -1.97683264350375 0.0490703932573001 CACNB3 other 1 1 1 1.20824981884605 -1.97683264350375 4.28882462083187e-13 195.258348891075 30.7817758371456 6.34331007814852 9.8664325945056e-10 -115.194509214573 69.5485393243194 -1.65631816762387 0.0988590807237984 DHRS13 other 5.35416865664651e-09 1 1.27523641283985e-05 6.34331007814852 -1.65631816762387 9.70835734900021e-10 166.210295063356 34.875616710354 4.76580232096687 3.12119464826485e-06 -151.497628858942 72.5207903459943 -2.08902341157828 0.0376706359147504 TP53I13 other 1.04937634585343e-05 1 0.0333655707899513 4.76580232096687 -2.08902341157828 0.000111824204887348 293.158050513022 131.026191957692 2.23740037112337 0.0260702099878279 -915.336424625099 336.226498401039 -2.72238038637073 0.00690013516624926 KMT2D other 0.82403256581487 1 1 2.23740037112337 -2.72238038637073 0.0199852640914509 44.1803852046606 19.1334825038114 2.3090613638087 0.0217185642578788 -17.1214664116702 39.8145773716555 -0.430030093044745 0.66752723514543 CORO6 other 1 1 1 2.3090613638087 -0.430030093044745 0.0416345084368476 10.3864678468072 4.21953625451009 2.46151880688441 0.0144559706780478 2.93763859134813 10.8277580118353 0.271306265631089 0.786361276256313 RHEBL1 other 1 1 1 2.46151880688441 0.271306265631089 0.108917485345904 1036.62703423911 514.803452208425 2.01363652437088 0.0450324371330588 113.271404141764 1321.03787429536 0.08574425180821 0.931732804910721 TUBA1A other 1 1 1 2.01363652437088 0.08574425180821 8.36535454159192e-07 3616.01992896604 706.563077393999 5.11775953861463 5.85201347575514e-07 98.9600762957055 1813.11252248219 0.0545802177573772 0.956512966538932 TUBA1C essential 0.00748950192108725 1 0.00658936717370029 5.11775953861463 0.0545802177573772 0.273124411967132 9.16771198410237 5.72733609663122 1.60069390540827 0.110609787875211 10.5733070181239 13.2287622025404 0.799266541815492 0.424835843605286 ZNF610 other 1 1 1 1.60069390540827 0.799266541815492 0.0998457983664388 15.4835682886505 25.025731271018 0.618705927949521 0.536629801727017 -96.6881502584544 57.7888623655284 -1.67312776719636 0.0954560469688655 ZNF528 other 1 1 1 0.618705927949521 -1.67312776719636 0.0154289129580901 19.7068836340521 8.7429220402422 2.25403858610938 0.0249927778717362 -19.7912875973109 22.2238629727819 -0.890542189787157 0.373964741629628 ZNF701 other 1 1 1 2.25403858610938 -0.890542189787157 2.88067572073546e-11 124.008586673456 19.8324809205347 6.25280251978239 1.56903529260168e-09 -180.70302897193 87.0414140745503 -2.07605805688266 0.038834840257471 SERTAD3 other 3.35541107951267e-07 1 2.01247222661022e-05 6.25280251978239 -2.07605805688266 0.0265349177242296 52.686183762516 36.459750446847 1.44505058638086 0.149590517625374 -154.238477798936 93.0743782720813 -1.65715292073244 0.098637277254683 NCKAP5L other 1 1 1 1.44505058638086 -1.65715292073244 1.35531749983139e-35 352.814123247737 27.5030734792289 12.8281707684122 9.80082301954374e-30 -325.321275573875 97.1151785909883 -3.3498499440958 0.000923841623606078 RAB4B other 2.14275696723343e-31 1 1.54480572434048e-25 12.8281707684122 -3.3498499440958 0.418257359882486 -17.120192186436 38.767719174256 -0.441609476933191 0.659121406076125 100.769851541022 98.966156239354 1.01822537491813 0.309472369320626 GPD1 other 1 1 1 -0.441609476933191 1.01822537491813 7.73912332252039e-23 135.135983221518 12.8655522853573 10.5037063488771 7.50243554309391e-22 -52.4672228548793 51.4728627403719 -1.01931814283427 0.308967814646561 PROSER3 other 1.16667284086995e-18 1 1.15852609656456e-17 10.5037063488771 -1.01931814283427 0.00030442525191659 648.808002864886 185.894966250756 3.49018596872442 0.000562937892570693 -537.198763602335 568.622392492279 -0.944737264474911 0.345631464813797 CYP2S1 other 1 1 1 3.49018596872442 -0.944737264474911 0.112841956184279 23.3500013900341 56.1037325662693 0.416193367570568 0.677595512089118 -311.767033326846 170.66877266107 -1.82673741930507 0.068831132645616 AXL other 1 1 1 0.416193367570568 -1.82673741930507 0.206646966473912 8.49497339817868 5.76794646414458 1.47278991769188 0.141981134004961 -14.4554367035191 23.0428320039622 -0.6273289976264 0.530977694801754 NFKBID other 1 1 1 1.47278991769188 -0.6273289976264 0.00531269279302597 197.967796690333 88.6643446986208 2.23277798266311 0.0263744806116962 -320.294666677687 226.662056370577 -1.4130934476039 0.158767363363627 TMC4 other 1 1 1 2.23277798266311 -1.4130934476039 0.615595683445469 -13.7327555330244 48.2738535918021 -0.284476057145695 0.776261242208489 -121.294409530605 123.407565479027 -0.982876609385991 0.326538417909023 LAIR1 other 1 1 1 -0.284476057145695 -0.982876609385991 0.343902109652824 7.42803362845023 17.0176508304913 0.436489954015337 0.662826290383578 60.8985442551397 41.748839622657 1.45868830859889 0.145800460709055 TTYH1 other 1 1 1 0.436489954015337 1.45868830859889 0.00021587404775206 189.951589911466 166.575845977169 1.14033093331851 0.255147878662417 -1342.60289660987 408.655010493505 -3.28541890380471 0.00115140337896336 LENG8 essential 1 1 1 1.14033093331851 -3.28541890380471 0.0882065883154116 9.36697253142839 11.8885196290432 0.787900665827664 0.431438379282611 -47.2002308059245 29.2651806824611 -1.61284604110481 0.107933302718899 CDC42EP5 other 1 1 1 0.787900665827664 -1.61284604110481 0.45224852327375 -0.607413640363491 3.55866751053655 -0.170685695858085 0.864597342559863 -10.6950191548177 8.760135907101 -1.2208736563263 0.223187245561484 LAIR2 other 1 1 1 -0.170685695858085 -1.2208736563263 0.0140635366863196 12.9372515572884 4.39857208889374 2.9412389511484 0.0035535638999069 11.7359270530316 12.0212869299761 0.976262119138604 0.329811705043816 TMEM145 other 1 1 1 2.9412389511484 0.976262119138604 2.88910971566873e-23 79.7768388678269 9.25889200248993 8.61624034996553 5.90526567049141e-16 -88.9675032530012 25.1624778731558 -3.53572107252262 0.000478402556969734 ZNF526 other 4.37180082174992e-19 1 8.74333635172959e-12 8.61624034996553 -3.53572107252262 5.62545617680172e-10 172.655550452434 26.8314470201368 6.43482069091753 5.58104589572467e-10 -78.0631029699948 105.472312175787 -0.740128867563742 0.4598625140343 TRAPPC9 other 6.16099960483325e-06 1 7.27433522048753e-06 6.43482069091753 -0.740128867563742 0.399706745399394 -12.8187840648253 15.3665277935717 -0.834201729696402 0.404896654711164 -45.1696439659711 34.2928282705702 -1.31717464682653 0.188884566017617 NLRP7 other 1 1 1 -0.834201729696402 -1.31717464682653 9.49951086832693e-21 735.138803270953 75.1458419996832 9.78282741544172 1.56134486090943e-19 -415.488151384049 302.817724711326 -1.37207342066958 0.17118368993737 ZNF146 other 1.40203280905637e-16 1 2.3841736026087e-15 9.78282741544172 -1.37207342066958 1.16172730582423e-11 13.4325422952509 3.37648670375546 3.97826008919587 8.90796829121922e-05 -41.602849263829 9.32454830108224 -4.46164767670306 1.19171432309288e-05 ZNF283 other 1.37443957552064e-07 0.183130740029683 0.839397852081587 3.97826008919587 -4.46164767670306 5.04812780660164e-06 35.3302865555821 7.15146356830228 4.94028756745374 1.38638283284079e-06 77.4011328287747 39.3514485595781 1.9669195331295 0.0502397010654525 PPP1R14A other 0.0424093217032604 1 0.0152224835045918 4.94028756745374 1.9669195331295 6.65362218448996e-15 3624.50087645982 441.716094608072 8.20549878237013 1.01819469546445e-14 -2512.86148918931 2430.57494579864 -1.03385476491186 0.302150185076731 SPINT2 other 8.77280085025001e-11 1 1.4835096712917e-10 8.20549878237013 -1.03385476491186 0.0526514460723859 50.636780634831 57.4822835135516 0.880911083201718 0.37916418148727 -640.759821512667 310.66507255206 -2.06254219777246 0.0401306801992322 C19orf33 other 1 1 1 0.880911083201718 -2.06254219777246 1.83935249875403e-17 184.491237323789 21.855890151295 8.44125936059658 2.07717880170358e-15 -301.737231170135 118.120945872674 -2.55447692990359 0.0111944785079319 YIF1B other 2.58024368525215e-13 1 3.05490686366545e-11 8.44125936059658 -2.55447692990359 0.552964867082928 5.21995306540014 10.1730798669859 0.513114330532305 0.608289373552156 -14.8362980652855 22.6186096563212 -0.655933246592777 0.512423574179027 DNAAF3 other 1 1 1 0.513114330532305 -0.655933246592777 0.548565667845144 -202.543739635467 209.930975189614 -0.964811121619978 0.335496424288214 -591.290663374895 785.042141039001 -0.753196080139499 0.451983517724253 PSCA other 1 1 1 -0.964811121619978 -0.753196080139499 0.526174949133563 510.709367672062 532.457089181227 0.95915591706628 0.338332004791533 1658.14015848874 1991.13662442942 0.832760614286772 0.405710347032928 LY6D other 1 1 1 0.95915591706628 0.832760614286772 3.27534180621719e-22 12290.9487472276 2268.24751962289 5.41869819801284 1.32302438611985e-07 -17816.8926709865 3854.22496031966 -4.6226914241946 5.85863274408792e-06 EEF2 essential 4.91334024350641e-18 0.0905217345289024 0.00155389214149776 5.41869819801284 -4.6226914241946 6.58981442032727e-21 307.201052831864 59.3972826859996 5.17197149330661 4.48793486199607e-07 -470.690232919327 106.362761050419 -4.42532920611385 1.39306356467858e-05 CHAF1A essential 9.74304062045387e-17 0.213709881457341 0.00509335727487934 5.17197149330661 -4.42532920611385 6.93872385972871e-17 205.75338090131 86.422784374819 2.38077704149116 0.0179624030395591 -910.433941077439 154.865284553274 -5.87887688130807 1.20223250998331e-08 UBXN6 other 9.61776514196997e-13 0.000190950589560649 1 2.38077704149116 -5.87887688130807 0.107358183946262 -19.7517106410791 13.5768523850904 -1.45480779203062 0.146871292299512 -52.0491476825486 24.7781197259625 -2.10060925761092 0.0365924631258437 PLIN4 other 1 1 1 -1.45480779203062 -2.10060925761092 0.0112688863212317 -8.61173510724176 22.2544441228324 -0.386966983300489 0.699082125363735 90.9869785531283 40.8976230026798 2.22474979895938 0.0269155958964963 SEMA6B other 1 1 1 -0.386966983300489 2.22474979895938 7.687726531332e-47 186.449397600544 10.8882173691612 17.1239598989479 3.78066902284004e-45 -138.147435753709 66.4352885109234 -2.07942855145416 0.0385112787167912 ZNF444 other 1.22334792293086e-42 1 6.0150444153385e-41 17.1239598989479 -2.07942855145416 1.1593774025996e-06 578.615891701 112.138233359067 5.1598449018567 4.80478634887353e-07 -1.97787789608852 337.808443708381 -0.00585502799863687 0.995332729965375 NXN other 0.010279040051448 1 0.00543805718965506 5.1598449018567 -0.00585502799863687 1.18571413821091e-21 666.322424955856 62.4700441462654 10.6662710753933 2.20313872910595e-22 282.716752100167 188.186560099196 1.5023216958275 0.134187024576183 FAM57A other 1.76766263724483e-17 1 3.40935718329145e-18 10.6662710753933 1.5023216958275 4.73120470469402e-32 539.810241318421 41.4389095343229 13.026651699686 2.0959616698307e-30 -110.347238482529 124.83176450568 -0.883967625704018 0.377503054627451 GLOD4 other 7.44171188001322e-28 1 3.30826589966078e-26 13.026651699686 -0.883967625704018 2.35870761689191e-11 128.240233715353 18.1338897178705 7.07185472673168 1.35894790013886e-11 0.396667574126902 67.961016544073 0.00583669277327041 0.995347410787122 MFSD3 other 2.75520636729144e-07 1 1.86257399193032e-07 7.07185472673168 0.00583669277327041 0.00482499134231096 16.589016729336 5.04342023497927 3.28923943602414 0.00114061170949306 11.7497033696794 18.9014034694587 0.621631266094332 0.53471875613128 GPT other 1 1 1 3.28923943602414 0.621631266094332 0.0127269756965633 159.471697475964 64.4847489377157 2.47301416386057 0.0140255938594754 -228.90639820855 241.671762516439 -0.947178916663792 0.344410514805732 KIFC2 other 1 1 1 2.47301416386057 -0.947178916663792 0.0938120358750918 143.747352264006 76.5373014735849 1.87813457616633 0.0614364219857707 -139.823290907097 237.056590622144 -0.589830852372158 0.555795506032844 SLC43A2 other 1 1 1 1.87813457616633 -0.589830852372158 0.0871545456446222 13.9372217958558 11.9159462150973 1.16962778652001 0.243178454108908 -55.977339007884 36.9068876143054 -1.51671795229318 0.130503507160017 RILP other 1 1 1 1.16962778652001 -1.51671795229318 0.426720821800449 25.5033164515599 25.5520359462013 0.998093322397323 0.319121192763163 -43.960758046072 79.2459121012401 -0.554738495405419 0.579529404502251 SERPINF2 other 1 1 1 0.998093322397323 -0.554738495405419 1.34307811629791e-08 259.595392909655 44.1032970402738 5.88607678633642 1.16092108806401e-08 -58.605700197531 136.779942231883 -0.428467063527317 0.668650209489779 WDR81 other 0.000135718043651904 1 0.000143756858334966 5.88607678633642 -0.428467063527317 4.08755275573098e-36 298.266333961079 21.2268290761951 14.0513843537549 4.3298516705721e-34 -108.012730696799 66.3810412293794 -1.62716234479604 0.104860458061179 SRR other 6.46609970429084e-32 1 6.85935101652032e-30 14.0513843537549 -1.62716234479604 1.41843842193024e-33 821.130690521028 60.4082808960729 13.5930153671102 1.82380714813897e-32 -165.79043314501 188.910202761049 -0.87761502937307 0.380927182815135 TSR1 essential 2.23716107906837e-29 1 2.8845333854966e-28 13.5930153671102 -0.87761502937307 0.061602691694324 40.7397450234848 18.3958673579975 2.2146139799042 0.027612514883932 -9.33714274600507 55.6937308815334 -0.167651593782901 0.866981503778842 TRPV3 other 1 1 1 2.2146139799042 -0.167651593782901 0.022960913947742 25.1088206812345 9.149584610735 2.74425799087915 0.00646684139120964 21.0267480235649 17.5858805777785 1.19566079904661 0.232866478362218 HSD11B1L other 1 1 1 2.74425799087915 1.19566079904661 4.3066386785636e-10 90.6003632658486 16.4011475416535 5.52402586683363 7.72314885864124e-08 -116.192580978814 49.6546903473979 -2.34001219554282 0.020003797356262 CYB5D2 other 4.74720781538065e-06 1 0.000918668556735375 5.52402586683363 -2.34001219554282 0.00873646443843981 63.29104699628 47.5357161586644 1.33144195798013 0.184158400840872 -328.756601995749 142.223898257465 -2.31154261712478 0.0215504159845184 GGT6 other 1 1 1 1.33144195798013 -2.31154261712478 2.66751867981217e-17 654.93498954966 84.0135986274635 7.79558309903852 1.3684197379938e-13 -329.394050619946 185.611127719076 -1.77464602832696 0.0770747918147125 C19orf48 other 3.7307916255853e-13 1 1.95861917099052e-09 7.79558309903852 -1.77464602832696 0.00964038333715057 37.7567403110984 15.4047532431723 2.45097988361695 0.0148765199096946 90.6261682860511 34.0337001201212 2.66283618784288 0.00821028754103102 KLK1 other 1 1 1 2.45097988361695 2.66283618784288 0.76422036248293 14.8133682327963 33.9088201891236 0.436858851183143 0.662561596087447 -28.4198126203876 75.3397015305639 -0.377222261875542 0.7063036687356 KLK5 other 1 1 1 0.436858851183143 -0.377222261875542 0.787551522930763 -38.3028479634741 62.6618652131758 -0.611262493275099 0.541538205712969 8.96795610588883 139.224136852256 0.0644138028695812 0.948688227886287 KLK6 other 1 1 1 -0.611262493275099 0.0644138028695812 0.957367982567898 -24.116917301556 94.0334734041852 -0.256471620461088 0.797781281985371 7.6920401179832 208.926579593173 0.0368169532711507 0.970658061562074 KLK11 other 1 1 1 -0.256471620461088 0.0368169532711507 0.443581092432172 80.6627904974407 76.6650462113851 1.0521455928564 0.293670006554318 -45.2221744226952 170.336852393505 -0.26548673283116 0.790836373060415 KLK13 other 1 1 1 1.0521455928564 -0.26548673283116 0.110774770138402 -24.5468113959635 39.901775865015 -0.615180925255151 0.538951477378627 -213.4982621113 101.694941276087 -2.09939904023036 0.0367066447527118 ZNF83 other 1 1 1 -0.615180925255151 -2.09939904023036 0.037317951586958 -119.573133947529 134.299947212967 -0.890343864081458 0.37406521901404 -904.365888442365 350.543038059125 -2.57989972771854 0.0104060326334185 KRT80 other 1 1 1 -0.890343864081458 -2.57989972771854 0.164894858186786 -152.514472844128 100.531987197311 -1.51707408851664 0.130405069807224 -426.950596252129 268.182350035755 -1.5920160152046 0.112538306788393 KRT1 other 1 1 1 -1.51707408851664 -1.5920160152046 1.72806996773478e-10 433.308636209743 97.6539646936226 4.43718427172103 1.32515810758004e-05 -767.38974463473 208.863837722348 -3.67411493058389 0.000287406696048707 OTUB1 other 1.94304187172099e-06 1 0.134742076378739 4.43718427172103 -3.67411493058389 0.0629256890851699 77.8934877605717 37.4282450668948 2.081141865491 0.0383563661222853 -31.1992924378502 79.9531915762507 -0.390219474954864 0.696679671590008 RCOR2 other 1 1 1 2.081141865491 -0.390219474954864 0.294611055530379 15.7798793786734 86.4011555990629 0.182635050066906 0.855220430308508 290.115088969863 198.776061380083 1.4595071808729 0.145579485438887 ANGPTL4 other 1 1 1 0.182635050066906 1.4595071808729 4.75217364419433e-31 429.82524498151 36.2772062801164 11.8483557323183 2.08426838387148e-26 -9.07129284760054 83.3908660540986 -0.108780412973714 0.913456570707963 NDUFA7 other 7.45901175192742e-27 1 3.26688226488016e-22 11.8483557323183 -0.108780412973714 1.95888049296762e-26 482.514029936565 41.4529443215004 11.6400424103602 1.07108090128141e-25 224.535671512143 95.2883995743884 2.35637992153343 0.0191608777463296 CD320 other 3.02235671259974e-22 1 1.67656293477579e-21 11.6400424103602 2.35637992153343 0.00728708024771645 98.8649593583307 49.091795619909 2.01387947028436 0.0450031346041493 -213.324825149775 132.14919252427 -1.6142726343984 0.107623488384096 SPRYD3 other 1 1 1 2.01387947028436 -1.6142726343984 0.217581689213298 330.659769672329 197.38937329268 1.6751650008131 0.095046862403925 46.6154235360495 531.348384472632 0.0877304324211236 0.930155248234345 IGFBP6 other 1 1 1 1.6751650008131 0.0877304324211236 2.07000353319583e-19 186.54244967529 21.6104339261858 8.6320547894808 5.1524919263798e-16 -58.678152094513 56.4143675116878 -1.04012780223684 0.299204198534346 ZNF558 other 3.00109112242732e-15 1 7.63753878247278e-12 8.6320547894808 -1.04012780223684 1.86943834239415e-19 755.766426082419 85.8928643263593 8.79894310208124 1.73011416153187e-16 -509.7541588541 250.007498950704 -2.03895547531001 0.0424356275585599 NDUFV1 other 2.71143337180848e-15 1 2.57873515776326e-12 8.79894310208124 -2.03895547531001 3.3018872932508e-09 330.040839743894 61.2056943536804 5.39232245020757 1.52746183968398e-07 -322.247039146858 178.938875716822 -1.80087774585567 0.0728462943966742 CDK2AP2 other 3.45938731713886e-05 1 0.00178682486006232 5.39232245020757 -1.80087774585567 0.0526321215878388 18.8415003553113 23.2000722067956 0.812131108358894 0.417437175022407 -131.512735554243 67.5282175462007 -1.94752268507999 0.0525163041656864 NUDT8 other 1 1 1 0.812131108358894 -1.94752268507999 6.20700830405216e-15 1534.17562935738 248.755071605235 6.16741447503855 2.52402114128838e-09 -1361.21683925238 555.650261205593 -2.44977269748591 0.0149300858591545 PRDX2 other 8.19076815802724e-11 1 3.21206930440359e-05 6.16741447503855 -2.44977269748591 1.18911780205957e-08 79.1717635707695 12.8840149648455 6.14496054116615 2.82144010971359e-09 22.6577623596965 40.0030393311695 0.566401021985398 0.571586524554732 ZNF232 other 0.000120540871594778 1 3.58407537136917e-05 6.14496054116615 0.566401021985398 9.73450388209951e-20 183.049895432156 20.5128409901508 8.9236734940834 6.83690157665798e-17 -130.745711575603 59.9610849634255 -2.18050943633449 0.0300767625778029 MIS12 essential 1.41744111027251e-15 1 1.0224586307892e-12 8.9236734940834 -2.18050943633449 0.74136242002732 -4.44725319203738 5.83745722296485 -0.761847671369935 0.4468085802473 -0.661550647846398 13.1979581599771 -0.0501252269349176 0.960059250518638 CD300C other 1 1 1 -0.761847671369935 -0.0501252269349176 0.891793261700514 7.58115318099863 20.6087989818162 0.367860018804964 0.713262657148055 -9.73306892337029 46.5946141102927 -0.20888828267429 0.83469122677299 CD300A other 1 1 1 0.367860018804964 -0.20888828267429 0.813121534109339 -9.18162778128095 19.6588745544913 -0.467047478014621 0.640838444443603 -32.5100872228512 58.8937948471961 -0.552012097491777 0.58139166563577 TEKT1 other 1 1 1 -0.467047478014621 -0.552012097491777 0.0470974932745572 17.9856664211372 45.661786398697 0.393888803738314 0.693970613603688 -235.174116651999 102.960760165965 -2.28411402822704 0.0231327343708749 HID1 other 1 1 1 0.393888803738314 -2.28411402822704 3.56674454010404e-16 200.684643926494 22.646119802236 8.86176729960952 1.03698899983409e-16 28.5424189991965 51.0637426509939 0.558956659214655 0.576649512686254 MRPL58 other 4.85861941252972e-12 1 1.54832827565228e-12 8.86176729960952 0.558956659214655 3.25980847818737e-15 835.825140382262 99.285721814754 8.41838207050288 2.18308103104003e-15 -10.7058146635288 223.875021060614 -0.0478204965109985 0.961894265848983 ATP5H other 4.33489331429356e-11 1 3.20978403993815e-11 8.41838207050288 -0.0478204965109985 0.865613401633765 -1.20383129645108 6.42157547155431 -0.187466658576808 0.851434016276591 -10.1551616704692 18.9454975472814 -0.536019792836028 0.592381325153065 TMEM88 other 1 1 1 -0.187466658576808 -0.536019792836028 0.487353338289902 188.077131965508 156.777796140255 1.19964138159751 0.231326408494417 112.575725101849 360.05690763244 0.312660923080446 0.754778748616093 EVPL other 1 1 1 1.19964138159751 0.312660923080446 1.50408416427112e-22 629.175612228719 59.0275424260083 10.6590175767083 2.20025976220126e-22 -53.6385722127647 135.563038352943 -0.395672543670162 0.692657920202289 SRP68 other 2.26199217464734e-18 1 3.40512200798268e-18 10.6590175767083 -0.395672543670162 0.00603501702986833 17.9690278203394 6.82299189335105 2.6335994679768 0.00893397549214366 -15.4246548699984 15.0837930594137 -1.02259788431478 0.307409978837724 MGAT5B other 1 1 1 2.6335994679768 -1.02259788431478 0.901423620460675 6.53096398182119 43.8698823847359 0.148871244389148 0.881765544752481 -36.2982859414922 97.146044676652 -0.373646565460385 0.70895834890139 TMC8 other 1 1 1 0.148871244389148 -0.373646565460385 1.7601834522012e-15 1002.29549239383 118.060575257079 8.48967142681889 1.34532690601839e-15 36.715420891579 258.236986089047 0.142177235908874 0.88704488115147 TK1 other 2.35635758746174e-11 1 1.9824737287087e-11 8.48967142681889 0.142177235908874 4.84291173387388e-17 173.309982798854 20.6185777284908 8.40552559352207 2.8667599997502e-15 -64.7101753979085 64.2105953367607 -1.00778033685138 0.314500503706943 TMEM68 other 6.73455305712502e-13 1 4.20783032763335e-11 8.40552559352207 -1.00778033685138 0.117595350552744 2.43730845873377 1.26488130172568 1.92690686106952 0.0550563531662085 -1.52388973299994 5.62690175222462 -0.270822168238047 0.786737837707782 GSDMA other 1 1 1 1.92690686106952 -0.270822168238047 0.57708433081527 -91.9774267532505 193.245212856877 -0.47596225227774 0.6344919424002 -451.828298975386 431.28497674686 -1.0476328259414 0.29575878341688 KRT24 other 1 1 1 -0.47596225227774 -1.0476328259414 0.165940631024766 48.6215900962561 30.3425627831036 1.60242199855746 0.110235883864155 -20.5616968821145 68.4567939198507 -0.300360208311657 0.76413440561789 TMEM99 other 1 1 1 1.60242199855746 -0.300360208311657 0.000612390063841758 40.6128883117607 25.1037670567305 1.6178005563859 0.106873192475836 -115.063114886624 46.4559085545376 -2.47682412133958 0.0138685368062351 GHDC other 1 1 1 1.6178005563859 -2.47682412133958 1.69471884363212e-13 413.724578638361 81.8710415676569 5.05336894115932 8.15313745456031e-07 -372.554857648807 149.39927163598 -2.49368590334603 0.013259710107878 FAM234A other 2.14483616850081e-09 1 0.00909482483056203 5.05336894115932 -2.49368590334603 0.0116593929489877 345.571852329017 148.672922516899 2.32437653392962 0.0208446806577048 -245.017054501196 304.279719245333 -0.805236231678147 0.421389298124425 SOST other 1 1 1 2.32437653392962 -0.805236231678147 1.27048377887384e-12 389.887599930429 69.9578780106707 5.5731764744345 6.05406217497798e-08 -169.22599037166 128.194290677068 -1.32007431436985 0.187928250183689 ZNF598 other 1.55913769343398e-08 1 0.000724049655523215 5.5731764744345 -1.32007431436985 0.0503442180284293 2.69491932863253 11.2918621984354 0.238660309634839 0.811549368433607 -38.8664100947855 20.669540761384 -1.88037124498663 0.0611299376261043 RAB26 other 1 1 1 0.238660309634839 -1.88037124498663 7.02521096512714e-21 334.795619914049 42.1597612633428 7.94111754625014 5.36269397199884e-14 -109.213199472452 77.5312968631115 -1.40863372458838 0.160089773146172 MLST8 essential 1.03846668486509e-16 1 7.72442439726713e-10 7.94111754625014 -1.40863372458838 1.46907034481132e-08 144.252595124665 31.1910742053042 4.62480369143984 5.81247687118726e-06 -53.175983994114 57.3600125149056 -0.927056701396214 0.354721982097178 E4F1 essential 0.00014800883723974 1 0.0608275704569747 4.62480369143984 -0.927056701396214 0.0026215136910217 8.06105159744839 3.30377489045461 2.43995183229302 0.0153305344628512 -4.50607173938397 6.07560252063013 -0.74166664525589 0.458931587105021 DNASE1L2 other 1 1 1 2.43995183229302 -0.74166664525589 2.97849135592366e-08 183.360426505424 52.2349169704549 3.51030378030727 0.000524024375713237 -215.605267819345 95.9916477690821 -2.24608362112927 0.0255043870247847 ECI1 other 0.000295138708458476 1 1 3.51030378030727 -2.24608362112927 8.56162188366405e-10 133.186828919112 40.2584238665007 3.30829714945542 0.00106564943922384 -217.324027678359 73.400639120013 -2.96079203510783 0.0033402356907845 CASKIN1 other 9.2867912572104e-06 1 1 3.30829714945542 -2.96079203510783 0.190651568267101 -723.296530807542 807.261287081411 -0.895988129720135 0.371054281716306 -2724.94537054648 1495.02654212857 -1.82267357385293 0.069454695034838 ABCA3 other 1 1 1 -0.895988129720135 -1.82267357385293 3.73492230744148e-18 231.255972507812 45.1420319813821 5.1228525247421 5.72236302639921e-07 -345.021902428397 83.5495630577078 -4.12954765771892 4.8450833280698e-05 KCTD5 other 5.30433666102839e-14 0.731752935038382 0.00644681418554135 5.1228525247421 -4.12954765771892 1.32282517870234e-08 3157.90915222472 694.145763721835 4.54934585394975 8.12694866707557e-06 -1445.87427516659 1284.73559367547 -1.12542556015757 0.261404465827548 SRRM2 essential 0.00013372439731502 1 0.0840732839608968 4.54934585394975 -1.12542556015757 2.00823639518852e-06 0.30307268596289 10.2061498191255 0.0296951045530369 0.976331912901618 -81.2701935624023 18.2946587973072 -4.44229075069521 1.29446635206315e-05 ZNF597 other 0.0174555907469786 0.198700585041694 1 0.0296951045530369 -4.44229075069521 0.0690461266709977 -29.1357307873315 14.2365325860249 -2.0465468407618 0.0416637798371334 -51.3182149748268 25.5242507569854 -2.01056694918976 0.0453580920655438 NLRC3 other 1 1 1 -2.0465468407618 -2.01056694918976 1.74629940887596e-08 67.1407892815416 26.455829801724 2.53784476936597 0.0117164171624799 -239.111873701974 54.2225533926456 -4.40982319608735 1.49524512705932e-05 SDHAF2 other 0.000175258608674791 0.229176220624382 1 2.53784476936597 -4.40982319608735 1.16092388507591e-09 1189.69805859711 273.239379444109 4.35405050698582 1.89654180183927e-05 -1815.48613498556 578.93877295331 -3.13588624531799 0.00190197454404425 DDB1 essential 1.24905851832027e-05 1 0.190336935232589 4.35405050698582 -3.13588624531799 1.28901123846497e-08 106.71390248301 35.5019782929819 3.00585791592649 0.00289564785327674 -308.421742944037 75.7215030228293 -4.07310645763398 6.08986940313765e-05 VPS37C other 0.000130422157107885 0.916220851702059 1 3.00585791592649 -4.07310645763398 0.2685862952015 -4.81545740024885 9.41117426512798 -0.511674448330212 0.609295545274226 -32.6027842112635 20.0714763900292 -1.62433413355977 0.105466999850403 VWCE other 1 1 1 -0.511674448330212 -1.62433413355977 0.248613845328004 -6.54032827190433 21.6110673843861 -0.302637910269518 0.762398840637928 -72.1782567831683 43.7135676794581 -1.65116371448873 0.0998677425833913 RAB3IL1 other 1 1 1 -0.302637910269518 -1.65116371448873 0.0799960981386127 2282.04395929611 2473.03453736605 0.922770759896726 0.356950541324807 -8158.47179573898 5002.30556408767 -1.63094231074365 0.10406837103827 BEST1 other 1 1 1 0.922770759896726 -1.63094231074365 0.066421563944291 2777.04658486431 2773.91474418759 1.00112903278058 0.317660797794542 -9292.3389183569 5610.907955185 -1.65612036279617 0.0988591184544334 FTH1 other 1 1 1 1.00112903278058 -1.65612036279617 0.000328486435009795 80.9943999731421 91.9129983938667 0.881207243681289 0.378989412009632 -645.248891438826 187.252117839821 -3.44588300993629 0.000659873660946747 BSCL2 other 1 1 1 0.881207243681289 -3.44588300993629 4.32488547062951e-07 375.58232420518 84.413704323424 4.44930508873498 1.25901920854213e-05 -275.714355611999 172.872564109526 -1.59489943955083 0.111900251212863 POLR2G essential 0.00396937988494376 1 0.128243696582101 4.44930508873498 -1.59489943955083 0.00307039553148872 1842.86547286763 577.098427117306 3.19332957130558 0.00157240233426677 -238.709808968005 1179.15259440513 -0.202441829921454 0.839723226345037 SLC3A2 other 1 1 1 3.19332957130558 -0.202441829921454 0.837249823433096 7.08075327789902 15.3487741916912 0.461323698522587 0.644936433772688 16.2674313459535 31.8456834919549 0.51082060619183 0.609892550819709 HRASLS5 other 1 1 1 0.461323698522587 0.51082060619183 0.000351683548331002 152.662851293504 52.7547679886791 2.89382092110166 0.00411407769242053 -190.864405360135 112.100085417088 -1.7026249770461 0.0897806837739989 C11orf84 other 1 1 1 2.89382092110166 -1.7026249770461 0.000208098887577543 104.754860692502 31.2464983083498 3.35253120713719 0.000918007824085581 -77.0491382040722 73.5102652735356 -1.04814120745406 0.295532167299906 ATG16L2 other 1 1 1 3.35253120713719 -1.04814120745406 1.35230222956334e-11 174.319526551609 27.9453254869397 6.23787783874901 1.69780286053915e-09 -90.4360473473942 73.9403275196832 -1.22309503326611 0.222356316264845 C2CD3 other 1.59747462378318e-07 1 2.17539480520881e-05 6.23787783874901 -1.22309503326611 0.000671319012441279 159.593028391942 44.8928827488609 3.55497394285716 0.000445632884959668 -33.7679836077655 140.122998914046 -0.240988159470376 0.809745846445402 TRANK1 other 1 1 1 3.55497394285716 -0.240988159470376 1.81209522986056e-12 3439.30775373486 498.959006383287 6.89296657588114 3.78097755451768e-11 -372.424591463227 1325.95969250486 -0.280871729033997 0.779021530237712 RPSA essential 2.21256827565974e-08 1 5.11566263126242e-07 6.89296657588114 -0.280871729033997 0.255922232704549 153.328354819317 94.8125540055698 1.61717355288531 0.10699567784968 78.9763164339965 247.678159458043 0.318866696227106 0.750071428791311 ENTPD3 other 1 1 1 1.61717355288531 0.318866696227106 1.62094835925156e-06 2688.56398370183 510.107064339894 5.27058763081623 2.76557173116542e-07 2200.75824148912 1332.54905057012 1.65154013696347 0.0997780855070488 CTNNB1 og 0.0142043704721214 1 0.00318455584843698 5.27058763081623 1.65154013696347 7.06221512940291e-05 15.1723331774764 6.05603555170114 2.50532432446082 0.0128166087493625 -37.6545432280185 15.8201385332336 -2.38016520202506 0.0179916324133303 ULK4 other 0.532208532151803 1 1 2.50532432446082 -2.38016520202506 1.24678265376319e-20 206.878476590982 21.4439124130853 9.64742219636858 9.83233725854082e-19 -78.6929693249457 68.347569443875 -1.15136456153815 0.250767473471998 FADD other 1.83700956205469e-16 1 1.49392532306269e-14 9.64742219636858 -1.15136456153815 0.0191508757023858 322.369451407559 174.745367827834 1.84479540381963 0.0661706610109524 -624.774798633866 416.604052538789 -1.49968488022736 0.13487311941657 LTBP3 other 1 1 1 1.84479540381963 -1.49968488022736 0.105968355650151 11.7567499453956 8.29683231117856 1.41701670040449 0.157626618738979 -20.8725365009493 19.1908687222081 -1.08762853850358 0.277725489814265 NAALADL1 other 1 1 1 1.41701670040449 -1.08762853850358 6.27589212899935e-07 86.1888772577394 17.1995728854591 5.01110567289757 9.77955627242852e-07 -25.3326648925659 39.745480036473 -0.637372221176321 0.524420520534355 SAC3D1 other 0.00568030996595731 1 0.0108533515511412 5.01110567289757 -0.637372221176321 0.458205035663261 -17.8459752365601 24.9983862302756 -0.713885091308288 0.475914889390624 -68.9895738817282 57.7660383088902 -1.19429297735155 0.233411525600871 BATF2 other 1 1 1 -0.713885091308288 -1.19429297735155 3.21723504032537e-06 585.837484722796 152.55791624511 3.84009888927395 0.000153173946397492 -723.632142691138 350.717253831295 -2.06329211005748 0.0400372339166059 SF1 essential 0.0274526665990964 1 1 3.84009888927395 -2.06329211005748 9.12584307002186e-08 153.520646441061 36.6458348707007 4.1893068334433 3.78907800925104e-05 -219.044407791305 84.2455566157434 -2.60007075257867 0.00983169784574349 MAP4K2 other 0.000875807159429998 1 0.370079249163549 4.1893068334433 -2.60007075257867 0.0300344767830481 -121.388662156749 47.7729729003749 -2.54094846493835 0.0116091676376774 -166.051301793582 105.283489031895 -1.57718274081207 0.115911510005769 CCDC88B other 1 1 1 -2.54094846493835 -1.57718274081207 1.36310123189529e-08 185.415289119318 71.8110058529193 2.58198986237679 0.0103466829345819 -347.527171253267 121.909193181921 -2.85070520263935 0.00469632738796909 SCARA3 other 0.000137659593409105 1 1 2.58198986237679 -2.85070520263935 1.42312887263331e-12 189.02890124615 35.8240343354821 5.27659446381575 2.69121615023795e-07 -74.0156554204664 60.8162923007226 -1.21703662983064 0.224645174469899 PBK other 1.74390212052486e-08 1 0.00310324134283938 5.27659446381575 -1.21703662983064 0.0340979805398647 56.6194099271388 43.9598183345332 1.28798098063705 0.198851268493081 -74.0890452743981 74.8741370532965 -0.989514513157734 0.32329413311486 SCARA5 other 1 1 1 1.28798098063705 -0.989514513157734 0.178950603859372 -20.0654226060114 25.9286261805203 -0.773871414023709 0.43968389321416 -79.8343949149388 44.1133281384982 -1.80975678516685 0.0714453880107473 PNOC other 1 1 1 -0.773871414023709 -1.80975678516685 1.84696250967968e-29 604.804610110054 48.4760548571729 12.4763579027216 1.48941491703776e-28 -199.349189645334 213.74184436032 -0.932663373622233 0.351820938094014 COPS6 essential 2.88754118763322e-25 1 2.34344543046721e-24 12.4763579027216 -0.932663373622233 3.83838311189049e-18 557.267957965785 103.13211283971 5.40343781021823 1.4250001943095e-07 -700.342611417893 178.926887648519 -3.91412727635231 0.000114644405461013 PAFAH1B2 other 5.45088785719569e-14 1 0.00166995772771131 5.40343781021823 -3.91412727635231 1.92761395106004e-06 57.5209959816304 16.2203702783292 3.54621966050183 0.000459752879546647 -49.8157768848069 31.4556917911138 -1.58368085545904 0.114424079682508 ANKS3 other 0.0167798794439776 1 1 3.54621966050183 -1.58368085545904 2.00164604199723e-10 159.243778879986 30.3743283160639 5.24270947567811 3.18106050031608e-07 -79.0423566711248 58.961695274846 -1.34057130316003 0.181178248259374 NUDT16L1 other 2.24464587149569e-06 1 0.0036493126059626 5.24270947567811 -1.34057130316003 3.06644907426896e-11 55.0984876677211 8.42924945388788 6.5365828795478 3.42698563409875e-10 -14.8453141474908 17.9254619541353 -0.828169125318751 0.408352196722363 KIAA1586 other 3.56689356318965e-07 1 4.49860404188143e-06 6.5365828795478 -0.828169125318751 8.353870844785e-10 208.864644101543 34.1143185872672 6.12249204295991 3.20790284620273e-09 -194.926927161108 96.1169803238169 -2.02801759381539 0.0435330106801699 RAB4A other 9.06979757618307e-06 1 4.0682623895543e-05 6.12249204295991 -2.02801759381539 3.80889323145604e-12 586.952464230107 83.9277776271072 6.99354231489303 2.09217909397241e-11 -163.237697297061 236.091558938071 -0.691416914824469 0.489895454458385 SETD5 other 4.59162079052026e-08 1 2.85205854090319e-07 6.99354231489303 -0.691416914824469 0.0180925192976312 -65.6637989585692 47.9181325477298 -1.37033301314828 0.17171287100999 -264.219094407969 92.6296049041408 -2.85242601090009 0.00467172150341457 VASN other 1 1 1 -1.37033301314828 -2.85242601090009 2.60125090732997e-05 120.755009333282 33.7947989845645 3.57318324007299 0.000419110103007439 -143.977103058081 80.5290033233942 -1.78789128284486 0.0749403933101565 FAM83B other 0.205160659061115 1 1 3.57318324007299 -1.78789128284486 8.86989784298377e-17 40.0996246638698 6.90398489080516 5.80818546072938 1.77806178133503e-08 -22.7058860989408 10.4803785754241 -2.16651392271124 0.0311500687767439 THAP9 other 1.22581988190036e-12 1 0.000218114838716368 5.80818546072938 -2.16651392271124 8.90517329310419e-07 727.056381284219 136.344904997684 5.33247928330414 2.03894710869466e-07 -119.178196449311 384.151321017633 -0.310237632747438 0.756617828279149 RNF187 other 0.00795944388937653 1 0.0023672175931945 5.33247928330414 -0.310237632747438 1.27337076571128e-14 230.186989918387 40.1190389202459 5.73759980581749 4.30879057893076e-08 -319.172107537206 101.940597693505 -3.13096170474525 0.00205154203079537 HOOK3 other 1.66505961324407e-10 1 0.000519166176855367 5.73759980581749 -3.13096170474525 8.91316755765102e-21 419.453763456596 55.9361888665733 7.4987905317814 9.05860965332713e-13 -284.30874684773 105.147189570765 -2.70391199240174 0.00728312361327797 MAPK1IP1L other 1.31585092653602e-16 1 1.27726396111913e-08 7.4987905317814 -2.70391199240174 0.031591958600425 2511.21470784771 1115.44843095097 2.25130506993208 0.025164602919144 559.545467365542 1743.55964750613 0.32092132217322 0.748516448910636 DDIT4 other 1 1 1 2.25130506993208 0.32092132217322 4.94331828588225e-14 246.155119467816 91.654105278535 2.68569660594858 0.00769133472256121 -548.001372640425 132.028265741147 -4.15063675618394 4.46262894073849e-05 RBPJ other 6.36303929758764e-10 0.674883374707882 1 2.68569660594858 -4.15063675618394 0.000491597886697666 168.517460639919 49.4466921034454 3.40806338040511 0.000759336219345542 -107.880000883256 114.278082292552 -0.944013048863416 0.346049593475336 LMBRD1 other 1 1 1 3.40806338040511 -0.944013048863416 2.47238646754157e-25 43.2600173152483 8.82991017896705 4.89925904549903 1.6698611626573e-06 -62.7565631451596 12.7195363921374 -4.9338718967739 1.42009349064853e-06 ZCCHC4 other 3.79362979579579e-21 0.0221676593890236 0.0182248647292418 4.89925904549903 -4.9338718967739 0.23303148348061 -2.09908857010415 1.2468228118643 -1.68355002020336 0.0934330587887643 -2.47689914541873 2.38126379042277 -1.0401615962837 0.299202302442605 PTGDR other 1 1 1 -1.68355002020336 -1.0401615962837 1.10487558882854e-14 200.487834242998 29.5263874367176 6.79012407707153 8.34855079037279e-11 -143.442358482252 69.712744465206 -2.05762030433108 0.0406806184660788 TTC39C other 1.4479394591598e-10 1 1.11853883489415e-06 6.79012407707153 -2.05762030433108 0.0389619292897323 16.6944953860317 14.1141274994346 1.18282163645613 0.237916506769376 -58.4179422358932 33.3609508088071 -1.75108744863684 0.0810622399553987 GLYCTK other 1 1 1 1.18282163645613 -1.75108744863684 0.456378734064846 73.7423580162269 82.1640340230464 0.897501673244801 0.370242088146622 -166.2030434617 222.538299373568 -0.746851413574881 0.455795974652736 GNG4 other 1 1 1 0.897501673244801 -0.746851413574881 0.000166163016504877 92.5751967911593 31.0647381709524 2.98007329988454 0.00314232527081391 -60.7295422024609 50.3432949493754 -1.20630845206953 0.228746756796501 UBTD2 other 1 1 1 2.98007329988454 -1.20630845206953 0.129430427747742 168.835494419685 119.901630353101 1.4081167530623 0.160251140322959 -511.704250503539 488.572313899957 -1.04734598327714 0.295880171366966 POLR2J3 other 1 1 1 1.4081167530623 -1.04734598327714 9.60960327118414e-12 258.531768371 52.9705212326213 4.8806725392724 1.80721283106649e-06 -287.984751181919 98.5766825545047 -2.92142871639739 0.00377777289849149 NKIRAS2 other 1.140179428126e-07 1 0.019676933304652 4.8806725392724 -2.92142871639739 1.23470408654127e-09 287.165477470369 63.6628178628134 4.51072520995191 9.63181879882719e-06 -284.517643984954 118.474752389693 -2.40150444078671 0.0170015590894304 DNAJC7 other 1.32743036344052e-05 1 0.0990343608895411 4.51072520995191 -2.40150444078671 0.000950002997056872 536.85542853977 159.977142407287 3.35582584150044 0.00090402830204528 -565.808816413969 435.118670629979 -1.30035517803631 0.194579980464845 IRF2BP2 other 1 1 1 3.35582584150044 -1.30035517803631 4.974261634468e-07 786.13144047358 149.028133536097 5.27505392317863 2.72529500032445e-07 49.0080182917206 363.091309315488 0.134974363292011 0.89273270917067 NT5DC2 other 0.00454548028157685 1 0.0031406299583739 5.27505392317863 0.134974363292011 0.224182508293034 16.0749128919861 160.088895924177 0.100412416483899 0.920090613282635 -381.456445993031 259.453221950405 -1.47023206389762 0.142650469814338 FOXI1 other 1 1 1 0.100412416483899 -1.47023206389762 2.60956098924294e-06 56.8823248407641 12.589153698083 4.51835970907447 9.32778830216349e-06 -30.4425614194731 31.1009276431349 -0.978831299464245 0.328539562610607 SMIM4 other 0.0224239575805646 1 0.096021580955024 4.51835970907447 -0.978831299464245 2.19750931192232e-09 351.797400154009 54.0886573218173 6.50408824276928 3.7523658928821e-10 238.139841275338 147.141010045405 1.61844642225748 0.106729646804537 COA6 other 2.33133762901838e-05 1 4.92085263192559e-06 6.50408824276928 1.61844642225748 0.823059126360999 -3.62432276460926 39.4188482671383 -0.0919439030802606 0.926811042784799 -55.5872483364222 91.4976492370435 -0.607526518986428 0.544014055966573 KIF5C other 1 1 1 -0.0919439030802606 -0.607526518986428 1.61434232141426e-15 236.500090534557 40.5519550123596 5.83202685203402 1.58964555560092e-08 -185.955627635468 74.0021496116028 -2.5128408919396 0.0125704878378523 MGAT2 other 2.16338014492725e-11 1 0.000195494610427802 5.83202685203402 -2.5128408919396 4.69039126452453e-12 262.295009627258 71.2656793928699 3.68052352635679 0.000280991092315571 -414.949509078107 119.23324542908 -3.48014941289944 0.000584150638003577 BMI1 other 5.62424816529136e-08 1 1 3.68052352635679 -3.48014941289944 1.50009564561657e-19 158.227309540965 24.8511797299821 6.3669938916449 8.24946545120585e-10 -138.063327459884 44.7768865414683 -3.08336148678007 0.0022588441162187 THAP11 essential 2.17933895395176e-15 1 1.06896573316725e-05 6.3669938916449 -3.08336148678007 2.21331584446199e-05 311.140359809912 84.6661652413035 3.67490790356624 0.000287134190890662 -285.258995247794 197.693080352042 -1.44293869436309 0.15020116393686 MMADHC other 0.176002875951617 1 1 3.67490790356624 -1.44293869436309 2.48464698776334e-07 246.338688608783 51.933365830075 4.74336074066138 3.3919478374263e-06 -177.971106074644 123.729322174749 -1.43839069790819 0.151468620978224 PDHB other 0.00231916949837831 1 0.0361523354761174 4.74336074066138 -1.43839069790819 0.0745592762725977 41.3519660820152 24.760735650962 1.67006209609158 0.0960531900445288 -56.2142705623591 58.9915363596076 -0.952920944789122 0.341473071044212 PXK other 1 1 1 1.67006209609158 -0.952920944789122 0.0884220557215169 5.94667450671201 2.72727557357978 2.18044504351517 0.0300847573425786 2.20149869402751 4.78670035234755 0.459919888853669 0.645942491837234 HIST1H1E other 1 1 1 2.18044504351517 0.459919888853669 1.85231450919915e-05 137.727593161967 39.2128974837455 3.5123034001519 0.000529153707299567 -237.443377322084 128.927417806508 -1.84168256342832 0.0667352666611777 PCMTD1 other 0.148277776461392 1 1 3.5123034001519 -1.84168256342832 0.000136253195959652 51.6199801270532 13.1268744336783 3.93238926660386 0.000106705485868899 -11.6028313367344 31.2742925476146 -0.371002199940071 0.710923625050764 KCTD6 other 0.992740785762022 1 0.997909703845939 3.93238926660386 -0.371002199940071 7.9337961518953e-15 168.828320598276 23.9679113015432 7.04393129940389 1.5208696988992e-11 -138.226853357178 60.0332549971396 -2.30250472615159 0.0220591203011701 MPLKIP other 1.04329419397423e-10 1 2.08207061779301e-07 7.04393129940389 -2.30250472615159 0.252029845848925 -22.3637140081948 13.7292441878571 -1.62891079087766 0.104485261985479 -27.5718384708992 32.709416194847 -0.842932759993523 0.400003957919657 ACOX2 other 1 1 1 -1.62891079087766 -0.842932759993523 0.750551617767927 -172.007131373578 321.741880498293 -0.534612190079776 0.593353178756715 -520.903660864804 766.538123478014 -0.679553495005972 0.497363001245142 FAM107A other 1 1 1 -0.534612190079776 -0.679553495005972 5.08129663413148e-16 50.8163040663031 46.0874013147415 1.1026072769707 0.271183225374321 -440.298981519571 71.0784687517473 -6.19454793064528 2.1809423464234e-09 IRF2 other 6.89430327318959e-12 3.47118783856748e-05 1 1.1026072769707 -6.19454793064528 0.0501729561380954 12.8775704061271 5.7199044417549 2.25136110878386 0.0251580718453648 28.0597541012988 15.2003724508791 1.8459912210688 0.0659760202011661 MOBP other 1 1 1 2.25136110878386 1.8459912210688 0.103300310073907 -32.2569768877523 17.499338182284 -1.84332553332837 0.0663653594487451 -81.892193293744 46.5036541647183 -1.76098405092378 0.0793606346782911 CX3CR1 other 1 1 1 -1.84332553332837 -1.76098405092378 0.40107621070601 -2.79614185176772 7.27624420886984 -0.384283673211406 0.701067362352205 19.6507593227631 19.3362709367991 1.01626416939398 0.310403407734889 XIRP1 other 1 1 1 -0.384283673211406 1.01626416939398 0.00204259211161243 30.0894631888326 21.9914267603197 1.36823606384305 0.172379931417084 -113.699657101823 48.3158876808794 -2.35325609358138 0.0193299127919002 DEGS2 other 1 1 1 1.36823606384305 -2.35325609358138 0.100854076375123 193.709360939613 284.813999704654 0.680125840515163 0.497001127864294 -1165.71127287342 678.558814089581 -1.71792223263277 0.0869446846673687 ARF4 essential 1 1 1 0.680125840515163 -1.71792223263277 2.4972181256719e-18 1260.43687852639 311.077678431079 4.05183967195399 6.65510089060579e-05 -2775.77170648727 502.636343553942 -5.52242539180691 7.87846246247737e-08 SEPT2 other 3.55953471633272e-14 0.0012459788384408 0.635828339088477 4.05183967195399 -5.52242539180691 0.127278516037069 -3.67331616026398 48.9337789974498 -0.0750670852634418 0.940217130456427 -351.867450723207 177.468092970125 -1.98270824255964 0.048417190001655 FILIP1L other 1 1 1 -0.0750670852634418 -1.98270824255964 0.0300598953822835 96.1386742884154 46.7642091910244 2.05581738580683 0.0407651668040867 -124.922173781989 128.32648934664 -0.973471450968667 0.331193594537312 MFSD2A other 1 1 1 2.05581738580683 -0.973471450968667 9.20702419224118e-14 212.375928997266 50.4001749581266 4.21379348729864 3.43850026157138e-05 -321.323730333049 81.3974124776564 -3.94759145963335 0.000101024294104224 DTYMK essential 1.17532190966469e-09 1 0.337316875660153 4.21379348729864 -3.94759145963335 0.0552132183526343 864.597607299557 364.400040673967 2.37266056749188 0.0183535736113934 323.754317032808 715.846408103612 0.452267851550003 0.651435188787219 TAP1 other 1 1 1 2.37266056749188 0.452267851550003 3.74480917372011e-09 119.698806161938 42.0039315426743 2.84970481966262 0.00471706897686055 -241.970550002241 67.8372911265264 -3.56692529999364 0.000427966442414597 ING5 other 3.9122021437854e-05 1 1 2.84970481966262 -3.56692529999364 4.74569277184385e-15 156.676490891999 56.2272455812967 2.786487036173 0.00570902398882302 -511.606003689615 90.8300796113964 -5.63256143645859 4.48225222519815e-08 ATG4B other 6.28661921486155e-11 0.000710033574993639 1 2.786487036173 -5.63256143645859 0.000180211710483884 88.7791616230751 26.7877834538654 3.31416601810198 0.00104487261274119 -58.170404878296 60.4464950317946 -0.962345374164352 0.336737205065214 BDKRB2 other 1 1 1 3.31416601810198 -0.962345374164352 0.443514090421292 -0.851229691411884 24.5845022076178 -0.0346246462191177 0.972404631910472 -44.407384521921 41.8023205877248 -1.06231864397885 0.289040294026917 MLKL other 1 1 1 -0.0346246462191177 -1.06231864397885 7.11631587816987e-16 496.596120422923 78.4333289316398 6.3314426046578 1.00862432525774e-09 -196.914756703763 133.364309477332 -1.47651764910336 0.140970320770684 RFWD3 other 9.61698927775877e-12 1 1.30284004093542e-05 6.3314426046578 -1.47651764910336 0.0415742000921961 -43.6117985682305 23.1814151523402 -1.88132597952406 0.0610115101537865 -84.9007109645991 33.7052482076414 -2.51891665183914 0.012354082543097 RHOH other 1 1 1 -1.88132597952406 -2.51891665183914 6.28814813394128e-16 110.012065411838 22.8126165893433 4.82242205671527 2.36367795002488e-06 -178.223240611764 42.9587099347676 -4.14871025881351 4.47453514666677e-05 COG7 other 8.5128949437297e-12 0.676639204878948 0.0255088124366686 4.82242205671527 -4.14871025881351 5.83357352056706e-11 158.645085380578 30.647396912388 5.17646199558475 4.4109984172489e-07 -149.803959082092 57.4356790096784 -2.6082038493329 0.00960680914778572 CDC40 essential 6.70685947659594e-07 1 0.0050100120023113 5.17646199558475 -2.6082038493329 7.55122596932395e-09 1064.97490987583 211.015477282363 5.04690425361912 8.21033081920285e-07 -929.32513685522 465.042142852355 -1.99836756977586 0.0466684848017638 STIP1 other 7.75208858010797e-05 1 0.00915698196265694 5.04690425361912 -1.99836756977586 0.0192734741056203 -90.6862117912423 85.3609773151847 -1.06238488175217 0.289003316644885 -451.018460053597 160.744272796146 -2.80581355844368 0.0053813977057155 SCNN1B other 1 1 1 -1.06238488175217 -2.80581355844368 2.95737786236144e-05 282.620072483663 205.082527858922 1.37807971958528 0.169311256444736 -930.282165724012 340.87962833078 -2.72906354151881 0.00676554683025715 HR other 0.231769703073266 1 1 1.37807971958528 -2.72906354151881 0.484969183319461 180.23403461679 173.461361121233 1.03904427736401 0.299724156411979 -51.2780128598307 381.877239033657 -0.134278788098474 0.893283287396328 RAB31 other 1 1 1 1.03904427736401 -0.134278788098474 8.52817244581452e-13 287.890349788591 108.013017280564 2.66533013368931 0.0081512087666179 -773.208027016637 179.534734479248 -4.30673222794116 2.31585807174726e-05 REEP4 other 1.05391155085376e-08 0.35305256303787 1 2.66533013368931 -4.30673222794116 0.348458451315514 -152.100319556984 214.688535124559 -0.708469688279994 0.479278714224151 -597.321121310426 411.539286683211 -1.45143159022439 0.147846977294051 TNXB other 1 1 1 -0.708469688279994 -1.45143159022439 0.0251917672792802 -44.9503761462856 75.8947401264575 -0.592272614299599 0.554160063899431 -313.894821810994 126.149073139789 -2.48828480462286 0.0134349122660152 LGI3 other 1 1 1 -0.592272614299599 -2.48828480462286 0.659205612144745 -8703.07349953329 16897.3502615785 -0.515055518457383 0.606932532671945 -25634.1524078854 28086.0711883959 -0.912699830315764 0.362208680859336 SFTPC other 1 1 1 -0.515055518457383 -0.912699830315764 0.000399944874259818 22.9418538246119 142.44646422077 0.161055972502452 0.872168872703004 -736.392965789906 236.768574522412 -3.11018034076225 0.00206844689705941 BMP1 other 1 1 1 0.161055972502452 -3.11018034076225 8.56426862584674e-11 846.430901443902 169.417717146862 4.99611797218446 1.06558503567301e-06 -653.735293995892 341.446445792674 -1.91460564914721 0.0566236040801987 ATXN2L other 9.77011764836596e-07 1 0.0117928295897932 4.99611797218446 -1.91460564914721 0.423554012191976 -0.913273296359393 10.4868291693258 -0.0870876488606052 0.930665919639002 -19.1712887815058 17.4307702705285 -1.09985321841572 0.272368548512998 PHYHIP other 1 1 1 -0.0870876488606052 -1.09985321841572 0.00538181586590233 5.5210490996533 2.58013508434012 2.13982947372127 0.0332616716777584 -2.22912425903142 3.96488576370346 -0.56221651565297 0.574433237024986 CCDC110 other 1 1 1 2.13982947372127 -0.56221651565297 1.6313511711121e-25 250.922775782691 31.63680922472 7.93135533992561 5.6565211799473e-14 -121.36259360461 52.6486569293078 -2.30514130241851 0.0219116022732552 POLR3D essential 2.50673420953085e-21 1 8.14425919488812e-10 7.93135533992561 -2.30514130241851 3.85412786905387e-07 429.214348047139 86.2248177555726 4.97785161186263 1.14736008567912e-06 -124.907220529298 174.41037684841 -0.71616851466276 0.474506252382404 FEN1 essential 0.00355157883133314 1 0.0126634132656405 4.97785161186263 -0.71616851466276 0.875349103513319 74.0417072018515 202.445472332069 0.365736543025284 0.714849114727145 231.977293374378 510.905780479526 0.454051025135494 0.650158227189846 CAVIN2 other 1 1 1 0.365736543025284 0.454051025135494 1.28383394492497e-07 282.496744925867 54.0290546351154 5.2286079561026 3.42592881595527e-07 -25.6916971669257 116.85048593917 -0.219868124299461 0.826140002290303 MTCL1 other 0.00122054093144017 1 0.0039213181227424 5.2286079561026 -0.219868124299461 8.23998163750764e-05 28.7863531300443 7.23071104195753 3.98112342797357 8.79941933235084e-05 -3.96581324904138 15.1914855694681 -0.261054998927286 0.794246915913853 HEXIM2 other 0.617092224832947 1 0.82946288485337 3.98112342797357 -0.261054998927286 2.42976671071118e-17 363.640927978941 65.7789044158768 5.52823023138054 1.19864798207411e-07 -750.947099350465 167.141113352904 -4.49289276759156 1.29404387482441e-05 FNTA other 3.40215934833779e-13 0.198648675224295 0.00141104840449764 5.52823023138054 -4.49289276759156 0.00403389748004098 43.2931013319532 774.933631164211 0.0558668505158466 0.955489505642039 -3034.994800406 1111.29867752238 -2.73103429509379 0.00673256436562604 SERINC2 other 1 1 1 0.0558668505158466 -2.73103429509379 8.52324262008768e-34 154.646296163156 31.9475216025244 4.84063515433812 2.18061648968851e-06 -353.378863405789 47.7901404689976 -7.39438846460459 1.79175139081635e-12 TRAPPC11 essential 1.34445629089263e-29 2.85963521974289e-08 0.0235811867194916 4.84063515433812 -7.39438846460459 0.0803286325053129 34.8720333864147 17.5662436053993 1.98517304950139 0.0481294932230009 9.76894184833324 29.1978778196825 0.334577119222957 0.738201954710595 GFRA2 other 1 1 1 1.98517304950139 0.334577119222957 3.63213296297181e-16 57.6463920243487 12.699806057407 4.539155303929 8.51275094698762e-06 -60.5416556825717 18.9975774322522 -3.18680926020547 0.00160759875655858 ING2 other 4.94623866897501e-12 1 0.0878909771119621 4.539155303929 -3.18680926020547 2.09365379854204e-13 147.097323076184 30.8817424125897 4.76324558086516 3.11327678293513e-06 -94.983192337497 46.1958466195527 -2.05609809729723 0.0407343160427167 CDKN2AIP other 2.64260982451977e-09 1 0.0332871553631424 4.76324558086516 -2.05609809729723 1.73305903754064e-12 150.106540785469 22.0456205730868 6.80890521034907 6.39896537138682e-11 -29.7362857094168 39.8074125595977 -0.747003731149243 0.455713730456384 SNRNP48 essential 2.11762483797091e-08 1 8.60980790720097e-07 6.80890521034907 -0.747003731149243 5.17467196738751e-09 197.534544222782 39.4269770208911 5.01013669189284 9.82472039777335e-07 -161.940922092861 80.7433184850469 -2.00562628749091 0.0458901045151403 TMEM223 other 5.36406496139389e-05 1 0.0109024922254091 5.01013669189284 -2.00562628749091 6.99095201636845e-05 169.633375722006 155.461148071565 1.09116250475596 0.276710040298395 -1370.74201674386 401.021397103404 -3.41812687962486 0.000785248404761099 SLC20A2 other 0.527257601074508 1 1 1.09116250475596 -3.41812687962486 0.436602893241584 -6.32320260835442 4.98751466482862 -1.267806319036 0.205947351653006 -4.57437655220001 8.33703698254305 -0.548681331482433 0.583672596560418 DYNLRB2 other 1 1 1 -1.267806319036 -0.548681331482433 1.61156748039975e-13 136.258136736435 25.6598543798486 5.31016796585731 2.27848189743924e-07 -189.608252644942 53.080318357429 -3.5721008937469 0.000418699278208113 TMUB2 other 2.0407279004302e-09 1 0.00263665925171669 5.31016796585731 -3.5721008937469 0.133347616390283 157.855386361771 346.665600744577 0.455353476153173 0.649220918609755 -1008.47333351544 647.700791506141 -1.55700494231353 0.120640657714823 STAT3 other 1 1 1 0.455353476153173 -1.55700494231353 5.06501902880152e-17 66.5156552349925 8.80449245399346 7.55474044444469 6.52505016454164e-13 -88.023684321495 29.1894041758797 -3.01560401134301 0.00280897137557595 ZSWIM1 other 7.03936344622836e-13 1 9.22968345774415e-09 7.55474044444469 -3.01560401134301 1.39360280832929e-08 543.366365580137 188.934904732517 2.8759448464507 0.00448336528567948 -1757.25931622812 479.07489770374 -3.66802628284401 0.000316470528966047 ADAM9 other 0.000140642395416592 1 1 2.8759448464507 -3.66802628284401 0.00357506208788099 28.1385338969432 8.30796743421182 3.38693358150033 0.000813647410222883 42.4805842170805 55.6866322595137 0.762850660803302 0.446228438066375 GDNF other 1 1 1 3.38693358150033 0.762850660803302 0.394030899124608 -11.9205164414956 11.0584555823826 -1.07795490542878 0.28200543370414 9.09889379799309 21.7865055260642 0.417638973221642 0.676539371767693 DPCR1 other 1 1 1 -1.07795490542878 0.417638973221642 0.375594453072602 54.4761075603383 85.3235384162956 0.638465171176423 0.52371010213814 -196.784796653033 185.490847782528 -1.0608868254446 0.289685890264355 AXIN2 ts 1 1 1 0.638465171176423 -1.0608868254446 1.67541649463777e-39 1229.96877688447 84.15944922377 14.6147436589577 4.57054278290462e-36 -223.296569395742 223.864271207563 -0.997464080316352 0.319429093645979 NDUFS5 essential 2.65721056049551e-35 1 7.24933790796502e-32 14.6147436589577 -0.997464080316352 0.653294339789303 -7.51058485827056 14.7914096100202 -0.507766673784939 0.612036176208384 44.8268149742852 65.838658563792 0.680858570817508 0.496551013761352 VWA3B other 1 1 1 -0.507766673784939 0.680858570817508 2.02594738756509e-09 15.7120633462836 2.7807297853302 5.65033806203426 4.06084193127748e-08 -23.7684226399539 11.6011316156449 -2.04880208478116 0.0414481273581699 ZNF30 other 2.15317688350418e-05 1 0.0004895344948155 5.65033806203426 -2.04880208478116 0.000465642435808934 27.0992156529651 7.10427332469064 3.81449508126085 0.000169049600139002 -19.5451869296438 46.9855394405233 -0.415983027169137 0.677751647791252 UGT3A2 other 1 1 1 3.81449508126085 -0.415983027169137 1.59885527437431e-06 241.402369629846 47.4613238753437 5.08629658675102 6.91720582627091e-07 -146.697601076991 205.201489919498 -0.714895399319673 0.475302994860301 FAM84B other 0.0140155653351652 1 0.00775142084891918 5.08629658675102 -0.714895399319673 0.451951686757982 -7.67011209223384 34.5751572535497 -0.221838820167517 0.824621189310442 -96.6712665981428 78.6112103145599 -1.22973894195645 0.219955542649635 LDLRAD4 other 1 1 1 -0.221838820167517 -1.22973894195645 0.783473935382702 14.2599993505158 31.7953757279956 0.448492871180634 0.654153287584041 32.4837358331258 46.4875606854804 0.698761891442319 0.485295687644594 SLC16A4 other 1 1 1 0.448492871180634 0.698761891442319 0.481894318851529 -54.3316212261731 71.8669616806064 -0.756002757812909 0.450301771494349 -496.745696581129 465.295546849871 -1.06759177031498 0.286651305917663 IL7R other 1 1 1 -0.756002757812909 -1.06759177031498 1.71939130243069e-12 232.948300573473 41.7159766458769 5.58415070923427 5.72121193244026e-08 -101.912430254968 72.6506184920149 -1.40277443427641 0.161832931853691 TMEM208 other 2.10144004983079e-08 1 0.000685401189506343 5.58415070923427 -1.40277443427641 0.143274030444391 23.2607696253191 13.9406615256646 1.66855565516 0.0964573444726204 -11.3654051257094 33.0798368710564 -0.343575005221796 0.731454691910163 LRP1B other 1 1 1 1.66855565516 -0.343575005221796 0.499566647032564 -1.42889584028816 3.0875872179556 -0.462787199007216 0.643886928384254 9.69210109477671 10.5510548252862 0.91859072436521 0.3591235320996 WFDC12 other 1 1 1 -0.462787199007216 0.91859072436521 6.66068267534688e-15 476.62804095736 137.285174593202 3.47180999237306 0.000600815227648531 -804.092189208094 203.937494606442 -3.94283645957222 0.000102401362863817 AHCYL1 essential 8.78144403917733e-11 1 1 3.47180999237306 -3.94283645957222 3.31265484942762e-39 507.449153224043 32.8134284843787 15.4646794517562 4.93827601896641e-39 -112.855861932659 212.582680842868 -0.530879851007606 0.595940065705739 DNAJC21 other 5.25287679473737e-35 1 7.84346380092436e-35 15.4646794517562 -0.530879851007606 0.258660829909115 54.6999777445316 41.1519410493676 1.32921987030724 0.184889263509789 -81.2209411590154 140.626435960672 -0.577565239452771 0.56403546152631 PKIG other 1 1 1 1.32921987030724 -0.577565239452771 7.05164728406498e-07 681.138016649628 258.320716905813 2.63679206533783 0.00885792856875571 -808.684421401097 378.034144224589 -2.13918354666043 0.0333244777032655 NPNT other 0.00635706002658458 1 1 2.63679206533783 -2.13918354666043 0.300997601747133 -13.206894954805 8.50346819937599 -1.55311863878954 0.121583741169024 -9.37545170430224 38.6487892127962 -0.242580735263969 0.808517143451542 FAM178B other 1 1 1 -1.55311863878954 -0.242580735263969 0.0440947823341302 223.745044409111 108.739918075461 2.05761645188882 0.0406015617770043 -545.716633524141 494.229657144319 -1.10417621774726 0.270514532054838 SEMA4C other 1 1 1 2.05761645188882 -1.10417621774726 1.73531141226182e-06 114.576938229796 22.9262499676721 4.99763102955602 1.05126867122464e-06 -94.2698908326841 104.22819308978 -0.904456731313393 0.366568622782336 CNNM3 other 0.0151666217431683 1 0.0116406979964705 4.99763102955602 -0.904456731313393 0.472864238271841 192.325860435743 202.706962237129 0.948787640607815 0.343567753097632 -3.1217135038428 301.810648834022 -0.0103432848241202 0.991754954268304 GSTM4 other 1 1 1 0.948787640607815 -0.0103432848241202 1.70805112028957e-14 115.832589619317 55.0647179447594 2.10357183224873 0.0363409094789849 -413.86060877796 81.0048171167552 -5.10908639150987 6.12944562715757e-07 TET2 other 2.22524899951326e-10 0.00962261669007467 1 2.10357183224873 -5.10908639150987 0.0224180356656164 20.2170743602249 20.4064811096839 0.990718304226933 0.322706894669596 -42.3309936553346 30.304453823446 -1.39685717162089 0.163599338351934 CXXC4 other 1 1 1 0.990718304226933 -1.39685717162089 0.00106860421601371 85.5463517921714 30.0612178487108 2.84573806100275 0.00476801585568594 -100.078368181104 62.6107645043274 -1.59842111773267 0.111110254179638 TCTN2 other 1 1 1 2.84573806100275 -1.59842111773267 0.00790932269956308 41.9770359848483 14.1433014470238 2.96798001103778 0.00327823942938788 -81.3856318870525 95.8107254361602 -0.84944176673916 0.396419997422027 SHOX2 other 1 1 1 2.96798001103778 -0.84944176673916 2.4325144467015e-07 51.3427658081566 23.9311855047653 2.14543344699463 0.0328101478733795 -153.107937312115 43.172424696529 -3.54642896219875 0.000460210321277123 PPIP5K1 other 0.00227148199032986 1 1 2.14543344699463 -3.54642896219875 2.42855861575547e-05 172.927832147717 92.9255550342347 1.86092869807458 0.0638371197829313 -295.546191141129 137.021991646314 -2.15692523214816 0.0318908847722623 TSPAN5 other 0.192123272092416 1 1 1.86092869807458 -2.15692523214816 4.3501795750252e-08 81.5591743399425 22.3770920475383 3.64476198098826 0.000322689265104066 -123.361580449343 46.5312030009425 -2.65115820123637 0.00851026835829193 ABHD15 other 0.000426143591169468 1 1 3.64476198098826 -2.65115820123637 1.37149954794265e-29 296.896081518428 28.3181311202395 10.4843105732437 1.05120204919809e-21 -138.229545783526 68.8836445378467 -2.00671068888608 0.0458078722872269 ZBTB5 other 2.14529959289189e-25 1 1.62200476191265e-17 10.4843105732437 -2.00671068888608 5.16089610456621e-11 276.199194785277 68.5054530390362 4.03178407750828 7.21388414343946e-05 -373.649777456994 124.30053856758 -3.00601897435745 0.00289698784026148 CHTF8 essential 5.94999711895438e-07 1 0.687122464662609 4.03178407750828 -3.00601897435745 2.45499249298092e-12 46.7060423526303 9.02675538379368 5.17417835831518 4.45008945358402e-07 -38.9676816174609 16.0016008729149 -2.43523644458721 0.0155249470406324 ADAL other 2.98060638572814e-08 1 0.0050526315655993 5.17417835831518 -2.43523644458721 8.41988734119214e-13 63.4635223380942 14.5378545168695 4.36539808982488 1.8046137650649e-05 -91.9567972337545 25.7710479166304 -3.56822111119561 0.000424663167104803 LCMT2 other 1.04095067199158e-08 1 0.181490006352577 4.36539808982488 -3.56822111119561 5.73129631720545e-08 170.866155369191 48.5329552251734 3.52062128869838 0.000505496989644222 -201.364317764095 88.2369339538687 -2.28208652251415 0.0232653448924143 SNTB2 other 0.000556967376106026 1 1 3.52062128869838 -2.28208652251415 0.260881459753253 2.69578483952119 1.72834475539186 1.55974948349352 0.120054438598589 6.66001032735545 11.2150854765553 0.593843920430028 0.553140873811261 IL12A other 1 1 1 1.55974948349352 0.593843920430028 2.63917257817443e-16 200.871374170511 23.6224800654977 8.50339903403697 1.40361850498812e-15 -119.832925050019 80.971634316639 -1.47993709230832 0.14008689206642 ZNF507 other 3.60590149355972e-12 1 2.0680915052495e-11 8.50339903403697 -1.47993709230832 8.52697043256574e-27 137.401498808836 20.5287806182886 6.69311545403862 1.24415097673004e-10 -122.550654158446 32.7249299144898 -3.74487140167056 0.000220301733006679 STX18 other 1.31852543798764e-22 1 1.65870208217648e-06 6.69311545403862 -3.74487140167056 0.00091061615372689 75.3356793663043 70.2997831472483 1.07163459108413 0.284834105429451 -239.633829882684 112.064886817876 -2.13834892165758 0.0333794394325458 NSG1 other 1 1 1 1.07163459108413 -2.13834892165758 2.19003212787426e-20 32.7128837779278 5.00427888278086 6.53698255916333 3.08792499078276e-10 -16.7089812842582 7.97732114520579 -2.09456043954052 0.0371353004227688 ZBTB49 other 3.21650018620892e-16 1 4.06123894787749e-06 6.53698255916333 -2.09456043954052 4.72864659332354e-13 279.977393110168 35.222419042451 7.94884056011972 5.88689317594903e-14 -16.9581930205785 238.659385140843 -0.0710560492333908 0.943408195153646 GFM1 essential 5.89378511391846e-09 1 8.47359403746104e-10 7.94884056011972 -0.0710560492333908 0.82149870406241 -17.0236871625441 27.1848727614594 -0.626219122374522 0.531696382707382 -13.437785296365 39.5466388941918 -0.339795888401999 0.734272480362817 FSTL5 other 1 1 1 -0.626219122374522 -0.339795888401999 3.13916160488301e-27 256.828070990807 33.8300181872221 7.59172133959459 5.02150424986474e-13 -263.355603279852 61.1386402777146 -4.30751488884267 2.30549186125355e-05 DDX19A essential 4.86381699060574e-23 0.351541399003941 7.12149732715817e-09 7.59172133959459 -4.30751488884267 0.490165325214598 -25.198314775805 38.7772134182676 -0.649822732335231 0.516365406641348 -176.517952527836 164.997793722099 -1.06982007786807 0.28566647996343 ATOH8 other 1 1 1 -0.649822732335231 -1.06982007786807 0.711157330448183 -7.79400906192318 21.6858266660722 -0.359405669976926 0.71957360106586 -88.2187978967389 112.377045672069 -0.785025067789847 0.433129696847227 SOX14 other 1 1 1 -0.359405669976926 -0.785025067789847 2.79579081482048e-10 73.6083283778189 17.3049635864619 4.25359625924926 2.90614465626922e-05 -76.1726286859989 30.8472473842713 -2.4693492984025 0.0141572695991689 ANKRD49 other 3.11184756337886e-06 1 0.28733338889837 4.25359625924926 -2.4693492984025 0.233773459093662 -9291.0094417695 8087.37450987367 -1.14882888512537 0.251654676076723 -47693.5452045871 34411.9350903352 -1.38595940854201 0.166915730063338 SFTPB other 1 1 1 -1.14882888512537 -1.38595940854201 1.21953609730251e-10 506.039957619454 71.7984508323884 7.04806234330586 1.5582462093268e-11 130.767195516933 305.254305507779 0.428387718559471 0.668715538507793 USP39 essential 1.38149049102428e-06 1 2.13261576208466e-07 7.04806234330586 0.428387718559471 3.42290430588171e-14 251.276226037233 56.8093156841717 4.42315178436913 1.40989072255216e-05 -242.295230803833 89.2444782312192 -2.71496047269257 0.00705397656844969 TNIP2 other 4.42581526750505e-10 1 0.14299111708124 4.42315178436913 -2.71496047269257 1.04971946038538e-10 265.807899289441 37.861990039136 7.02044184721112 1.84143384403247e-11 -23.2550081532889 160.971933802857 -0.144466228390904 0.885241716982166 C2orf68 other 1.19258627894383e-06 1 2.51503034417955e-07 7.02044184721112 -0.144466228390904 0.00494874736906003 41.7516339096411 12.8232513843232 3.25593195191382 0.00127675157439474 -6.1618974754958 54.5186233169738 -0.113023717412493 0.910097003003461 TMEM150A other 1 1 1 3.25593195191382 -0.113023717412493 5.48281478607306e-07 300.087889971396 56.5824395816566 5.30355163527946 2.39115918190336e-07 -221.766015388963 240.562757248838 -0.921863458521839 0.357435161029699 RNF181 other 0.00498826489236927 1 0.0027637017824439 5.30355163527946 -0.921863458521839 0.224370432351013 -54.737090428784 41.4907812001873 -1.3192590943199 0.188216975674028 -223.22922034692 176.399900741661 -1.26547248274159 0.206809349385118 VAMP5 other 1 1 1 -1.3192590943199 -1.26547248274159 7.03160774299216e-25 119.594015623136 10.3352515709462 11.5714663355977 1.8321236736446e-25 24.8583296410089 39.8959194544144 0.62307950238902 0.53375244294526 LRRC28 other 1.07597661683266e-20 1 2.86525821321278e-21 11.5714663355977 0.62307950238902 0.0755632361896549 292.860562285495 163.47539587225 1.79146568645936 0.0743595852404739 -837.087013142316 692.499233268241 -1.20879124904109 0.22782050289181 MAT2A essential 1 1 1 1.79146568645936 -1.20879124904109 0.161958791844871 59.6288446530322 65.2296095792017 0.914137690501289 0.361451153059852 -114.286409946654 113.859370755806 -1.00375058449747 0.316387688789547 PLA2G4F other 1 1 1 0.914137690501289 -1.00375058449747 2.70597330250636e-05 3.62542860611548 4.66503728805851 0.777148901981083 0.437769372824429 -45.0970665021695 12.4297656400775 -3.62815098916768 0.000342868894855515 ENHO other 0.213041278106326 1 1 0.777148901981083 -3.62815098916768 0.18740807780279 48.3913617706104 41.609378661856 1.16299169386472 0.245855914594409 -45.9249863452106 67.4390865455277 -0.680984703347175 0.496462621524713 ZNF608 other 1 1 1 1.16299169386472 -0.680984703347175 3.73993471137491e-06 62.702937711698 12.4889787504715 5.02066173419749 9.38390715727871e-07 108.110640906484 64.4474464893102 1.67750076683669 0.09460608939974 SLC35G2 other 0.0317483057648616 1 0.0104292744145996 5.02066173419749 1.67750076683669 0.0473595209558565 -116.843729548252 71.8377674773782 -1.62649444228686 0.104998200482631 -269.581048373023 109.844095593708 -2.45421519396137 0.0147439634756437 INPP5D other 1 1 1 -1.62649444228686 -2.45421519396137 6.16078341521799e-57 778.168969731429 41.0701082960181 18.9473318191098 1.26700809860124e-51 25.2328774587912 111.334917883038 0.22663938626424 0.820874394116325 LETM1 essential 9.81720837214986e-53 1 2.01809049945206e-47 18.9473318191098 0.22663938626424 1.80849431900201e-59 533.526674287609 26.9935313082172 19.7649825136141 1.60037660396065e-54 44.9123796888052 73.1754240800223 0.613763162338362 0.539884793712152 TMEM129 other 2.8827399444892e-55 1 2.5502001184113e-50 19.7649825136141 0.613763162338362 6.89002730293763e-05 181.318730182403 77.9132755575075 2.3271865915658 0.0206895763976519 -276.596609855078 126.470941705153 -2.18703684914372 0.0295915434450822 PPIC other 0.520472662463909 1 1 2.3271865915658 -2.18703684914372 0.00636409491315252 34.5530088543449 26.4127933501 1.30819214750772 0.191908523249027 -82.7451147818874 42.8881235849571 -1.92932466765485 0.0547268771050143 CEP120 other 1 1 1 1.30819214750772 -1.92932466765485 0.372167400722971 43.0445106855961 36.4546887938114 1.18076747079249 0.238741965868011 -2.59576717060786 71.0977611749374 -0.0365098299540111 0.970903020200903 STXBP6 other 1 1 1 1.18076747079249 -0.0365098299540111 6.41765446769427e-07 203.500188582205 80.0829063591828 2.54111892080288 0.0116036428647278 -330.18144465398 120.709959630737 -2.7353289294772 0.00664000843168542 MFF other 0.00580284316968916 1 1 2.54111892080288 -2.7353289294772 0.255170372412005 6.78707843586461 4.81455353922196 1.40970048013245 0.15978753842782 -0.951993891971485 9.85882845041149 -0.0965625780750603 0.923145945701294 GRM5 other 1 1 1 1.40970048013245 -0.0965625780750603 0.396670022574407 -61.8550280478849 146.467325070852 -0.422312812895048 0.673156795322044 -464.614432273649 343.465700316932 -1.35272439677362 0.177356152972608 LGALS9 other 1 1 1 -0.422312812895048 -1.35272439677362 4.27636309216644e-06 135.572936336784 110.393770780463 1.22808502126804 0.220488506516644 -693.497113314572 192.204866713612 -3.6081142229759 0.000367663303257628 JMJD7-PLA2G4B other 0.0361566499442672 1 1 1.22808502126804 -3.6081142229759 0.115069234255511 13.0873011647459 6.35718881594223 2.05866170467145 0.0405041457424561 9.74805457558027 17.4322994728435 0.559194992649481 0.576500921791211 CPLX1 other 1 1 1 2.05866170467145 0.559194992649481 0.0233687150805454 78.4481059467572 53.2984072847282 1.47186585759825 0.142230397424115 -150.437050233791 95.4809755364449 -1.57557093848888 0.11630440348001 PXDC1 other 1 1 1 1.47186585759825 -1.57557093848888 0.433432099591169 3.6279086950525 5.5473685349842 0.653987322488722 0.51367453922137 -9.6143971784919 12.3296976692618 -0.779775582207566 0.436203457090759 SIGLEC7 other 1 1 1 0.653987322488722 -0.779775582207566 2.67802777043952e-12 93.6951968181782 12.9076208764338 7.25890524017814 4.12980682204127e-12 -11.0432237184244 39.8585169458767 -0.277060577377222 0.7819448063259 E2F6 other 3.24684086888087e-08 1 5.73712763717973e-08 7.25890524017814 -0.277060577377222 6.1895526025355e-13 512.682218138189 84.774433170658 6.04760420050367 4.87965969178503e-09 -368.284403576032 163.840653711178 -2.24782064300873 0.0253948947429603 FEM1B other 7.68990015339011e-09 1 6.14056375614228e-05 6.04760420050367 -2.24782064300873 1.65844722542271e-08 105.017506696255 31.885000770628 3.29363350033208 0.00112798244438638 -112.250109437168 52.388544704793 -2.14264607023715 0.0330810895234542 COMMD8 other 0.000166657361682729 1 1 3.29363350033208 -2.14264607023715 2.13454660831942e-36 771.311281171382 54.4424087038516 14.1674716371764 2.84252582956696e-34 192.39166980705 149.390333056361 1.28784551095729 0.19892746348561 ATP5I other 3.37792000766548e-32 1 4.5036979243659e-30 14.1674716371764 1.28784551095729 3.47305622217405e-18 597.069073269486 61.4822738025797 9.71123929454335 5.82367755373281e-19 168.870627584133 205.973834403552 0.819864465178986 0.413124140400831 UQCRFS1 essential 4.9366021141982e-14 1 8.86072539800447e-15 9.71123929454335 0.819864465178986 8.96731131554765e-06 13.8489099885262 6.74602894844103 2.0528980966983 0.0410680402251358 -59.0241312013811 18.5111484853198 -3.18857207850664 0.00160213851313659 MFSD7 other 0.0737830375043261 1 1 2.0528980966983 -3.18857207850664 0.969226156695407 -12.5071146922681 50.1226532532754 -0.249530180077823 0.803138346570296 -11.1394365392307 75.5504979258851 -0.147443588659845 0.882890735539103 COL4A3 other 1 1 1 -0.249530180077823 -0.147443588659845 2.74841409294625e-15 446.682255327413 58.6205552261392 7.61989124129338 4.27252792024132e-13 -92.0827745601285 117.857649000644 -0.781305034852897 0.435305116909964 MAP2K1 other 3.66088757180441e-11 1 6.07168942745494e-09 7.61989124129338 -0.781305034852897 0.613000646587757 22.9002142676155 76.634100439243 0.298825381081771 0.765302301357905 -129.000752765676 170.268096086921 -0.757633142851505 0.449328910824646 KLK7 other 1 1 1 0.298825381081771 -0.757633142851505 0.059880746295726 671.052909122387 308.681572480634 2.17393252123752 0.0305694304792352 36.9338368044575 507.557453057496 0.0727677952160297 0.942044183062904 HNRNPH1 essential 1 1 1 2.17393252123752 0.0727677952160297 0.000379665850746988 137.339005399757 125.829353736076 1.09147032327467 0.276028315901189 -511.240507275809 189.353472111076 -2.69992676435271 0.00736859826532722 IRS1 other 1 1 1 1.09147032327467 -2.69992676435271 4.82727675114843e-20 155.264391784321 23.5617906929657 6.58966857857176 2.43710486729673e-10 -193.06927708697 44.2782095506335 -4.36036775304091 1.87253968557508e-05 UPF3A other 7.05989224855458e-16 0.286198965543296 3.21649100385823e-06 6.58966857857176 -4.36036775304091 0.287034210028171 1.17917908647747 2.01178809735396 0.586134835984171 0.558305393676776 -26.1122091645254 17.9588107107156 -1.45400547871162 0.147179291909386 ZBBX other 1 1 1 0.586134835984171 -1.45400547871162 0.0445345272062367 97.3874468274433 40.1476946845566 2.42572948690139 0.0159309308933993 37.865263357008 78.177966191198 0.484346999567651 0.628530830960095 ROR2 other 1 1 1 2.42572948690139 0.484346999567651 0.330463083929764 -1.5760713217597 1.84971907683727 -0.852059829784821 0.394936016052298 -8.60733046237981 5.94153648494458 -1.44867080833218 0.14858987005808 C8orf46 other 1 1 1 -0.852059829784821 -1.44867080833218 4.62380501267991e-18 81.1128009827766 8.95823648785049 9.05455008837789 2.73038016525424e-17 -58.6335926436303 34.992761966005 -1.67559201816056 0.0949672463350013 HSPBAP1 other 6.55794264948392e-14 1 4.09857366606314e-13 9.05455008837789 -1.67559201816056 8.03548811856799e-10 270.193562452928 54.1357284990705 4.99103955823864 1.07138599505619e-06 -128.31512773111 93.904587366524 -1.36644152676245 0.172924802178971 CHST14 other 8.73136138963598e-06 1 0.0118559574212918 4.99103955823864 -1.36644152676245 0.00142427019572969 -222.875019091429 344.346486264694 -0.647240578839851 0.518026152301183 -2339.5558578545 683.343431061748 -3.42368968736467 0.000713713537908559 PARM1 other 1 1 1 -0.647240578839851 -3.42368968736467 5.07635582390729e-11 227.686628017025 38.2818042326521 5.9476462141986 8.30252926136202e-09 -100.373837286239 75.8566347991001 -1.32320445735658 0.186874540511826 CSNK1G1 other 5.85456117171228e-07 1 0.000103457817125832 5.9476462141986 -1.32320445735658 0.454687614288587 16.5910265214689 20.6853990320734 0.802064610682347 0.423242467649408 -39.3775980715057 62.6948250564442 -0.62808370604837 0.530496194629617 FAM110B other 1 1 1 0.802064610682347 -0.62808370604837 0.0418367200039577 20.0742745631012 11.6827786027673 1.71827912225831 0.086883661118976 -14.0967438948028 20.2006823020129 -0.697835037651085 0.485876465100447 ARMC4 other 1 1 1 1.71827912225831 -0.697835037651085 0.000493682157976385 -8.96473623853045 124.527874422171 -0.0719897956993824 0.942662934084872 -578.148623853209 175.642494150965 -3.29162157852467 0.00112776537666679 AFAP1L2 other 1 1 1 -0.0719897956993824 -3.29162157852467 0.0731581796508568 44.2463333048631 19.7366881558447 2.2418317072999 0.0257756046583578 17.5232015166644 32.8888767130172 0.532800243364006 0.594605283925103 ZNF354A other 1 1 1 2.2418317072999 0.532800243364006 2.77245803722373e-12 312.2766674931 44.8397798904503 6.96427743972059 3.62406725092315e-11 -180.771470438275 154.429830296551 -1.17057352255805 0.243014066528087 UBE2V2 other 3.35883291209655e-08 1 4.90662465102486e-07 6.96427743972059 -1.17057352255805 1.44057745545219e-11 98.9971493139153 20.4501877420537 4.84089195476372 2.17012323232822e-06 -118.738822504173 37.9768314435777 -3.12661214721357 0.00196008323147817 ZBTB43 other 1.69973733968804e-07 1 0.023478563250559 4.84089195476372 -3.12661214721357 0.740304822724226 4.63724933003642 22.3015235621656 0.207934194141942 0.835435385154377 -27.9338276607588 46.335911302494 -0.602854824164325 0.54710573516733 CPT1C other 1 1 1 0.207934194141942 -0.602854824164325 0.61284256425157 107.448679749305 158.597829880343 0.677491487937582 0.498674273252124 -70.3065630101499 281.696090597891 -0.249583027087548 0.803099599882393 PCSK9 other 1 1 1 0.677491487937582 -0.249583027087548 6.49457488251764e-73 2732.62406449081 107.912243967337 25.3226507394094 1.02308898651327e-72 1367.76925544803 346.903472677073 3.94279493627687 0.000103136759709586 XPO6 other 1.03646920550099e-68 1 1.63295233137384e-68 25.3226507394094 3.94279493627687 0.000165368218174391 137.287480867319 50.8461406952935 2.70005705428155 0.00736578957773573 -314.323455241586 145.008206748671 -2.16762528334947 0.0310515337726774 MN1 other 1 1 1 2.70005705428155 -2.16762528334947 7.93310009049004e-19 134.285904859799 19.2470550331617 6.97695853357469 2.37647406204441e-11 -253.941053509671 60.2113048120413 -4.21749793169882 3.38599525933361e-05 NSMCE1 essential 1.1396691589998e-14 0.513757060698689 3.23461884584864e-07 6.97695853357469 -4.21749793169882 3.62282456521224e-05 20.4227217477781 10.3055196335497 1.98172653820305 0.0485276812211362 -100.413706609418 29.1695256559145 -3.44241822077959 0.000668376910642049 CCDC126 other 0.281421012225687 1 1 1.98172653820305 -3.44241822077959 0.168857483049877 76.9588501949934 113.992778279093 0.675120401106214 0.500179149309441 337.886790541075 183.458833267027 1.84175809103329 0.0666113181619543 RAB3B other 1 1 1 0.675120401106214 1.84175809103329 3.29853085930941e-20 433.920299586775 59.9246615314264 7.24109721269285 4.71898895164312e-12 -369.181009615385 121.33548144991 -3.0426467608965 0.00257788461245521 CD2BP2 essential 4.83300741506015e-16 1 6.54240628255802e-08 7.24109721269285 -3.0426467608965 0.064472317541638 17.0193493483032 7.26253789487868 2.34344379260378 0.0198324480723241 15.4645987121763 11.1538897800015 1.3864758409128 0.166745414735542 RSPO1 other 1 1 1 2.34344379260378 1.3864758409128 7.75901094797032e-08 94.7650814174308 33.6585373185327 2.81548424165338 0.00522657933045168 -189.579882015435 56.3560108959004 -3.3639691490163 0.000878812567012505 RGS14 other 0.000748279015822257 1 1 2.81548424165338 -3.3639691490163 6.88321763391796e-20 439.660020661154 62.5317035053709 7.03099381617505 1.70331760843288e-11 -405.010096153848 126.614221203872 -3.19877255732362 0.00154598194164526 TBC1D10B other 1.00488094237568e-15 1 2.32860550248859e-07 7.03099381617505 -3.19877255732362 1.02627560494103e-16 933.124111796724 137.996724903276 6.76192940412728 8.29598910147540e-11 -583.608873085782 231.054155997609 -2.52585317310554 0.0121099373665322 LMAN2 other 1.41564456945566e-12 1 1.11174549948872e-06 6.76192940412728 -2.52585317310554 1.063415336842e-07 93.8836994856936 36.1460985157959 2.59733977775406 0.00990635535331019 -211.970200816195 60.5210470830194 -3.50242124075325 0.000538776768251839 RAB24 other 0.00101705042815569 1 1 2.59733977775406 -3.50242124075325 1.78651222576567e-14 488.888578470702 85.4067249892831 5.72423984799848 2.74143821686246e-08 -424.667845165464 143.000341296145 -2.96969812320939 0.00324690763841648 PRELID1 essential 2.32586026672433e-10 1 0.000333221815259632 5.72423984799848 -2.96969812320939 0.606913357886116 21.2026224403763 29.4083297024536 0.720973365536203 0.471552006635999 -63.5065686225405 98.4946960285805 -0.644771456567698 0.519624779535785 THBS3 other 1 1 1 0.720973365536203 -0.644771456567698 7.23467848901078e-07 362.226142178592 67.4108987729557 5.3734062113397 1.67491139234961e-07 -139.665352942159 225.773311535667 -0.618608780604675 0.536697578822436 SLC50A1 other 0.00651627491505201 1 0.00195445410373276 5.3734062113397 -0.618608780604675 4.8013531782851e-06 827.118594158257 167.028300264998 4.9519667795577 1.29906581242188e-06 -409.902017438415 559.412990442597 -0.732735965094605 0.464357478703283 EFNA1 other 0.0403793802293777 1 0.0142910230024531 4.9519667795577 -0.732735965094605 0.122491382324915 285.617419373161 201.793414710435 1.41539514449969 0.158105060134616 -225.538663961631 397.730422625407 -0.567064149814986 0.571141731698202 CXCL10 other 1 1 1 1.41539514449969 -0.567064149814986 0.000756201357460123 15.1159499649482 7.81808744007856 1.9334588006087 0.0542134887035039 -26.1689070662237 12.9523343634941 -2.02040082751263 0.0443181998818514 SH3TC2 other 1 1 1 1.9334588006087 -2.02040082751263 0.479402512436487 -1.82955629384358 54.3059140758865 -0.0336898167534199 0.973149391369544 -113.742953139312 107.035773131919 -1.0626629752945 0.288884344217739 CXCL11 other 1 1 1 -0.0336898167534199 -1.0626629752945 3.49623641389681e-10 298.881999754932 43.4346392243995 6.88118987729577 4.71513109065648e-11 -67.5755111850407 276.018178179494 -0.244822683892568 0.806793759476972 NMD3 essential 3.87243145203211e-06 1 6.36495545927718e-07 6.88118987729577 -0.244822683892568 0.00433815341383555 15.4707601205646 32.7170948743639 0.472864726528241 0.636687523921599 -145.701049611848 54.2028668089012 -2.6880690670022 0.00762829816966115 ADRB2 other 1 1 1 0.472864726528241 -2.6880690670022 5.47582119660295e-05 100.773395333194 23.1327392456071 4.35631052004925 1.92631937020993e-05 -158.694714260098 147.625453211352 -1.074982063106 0.283410926187199 B3GALNT1 other 0.417805157300805 1 0.19324835921946 4.35631052004925 -1.074982063106 4.18046292488853e-07 144.425771453417 34.7778595588286 4.15280794406318 4.39531711180172e-05 -79.2422609912499 57.8910593299794 -1.36881691073519 0.172181741433874 GPRIN1 other 0.00384309956685002 1 0.427092963753773 4.15280794406318 -1.36881691073519 0.068557418161478 20.4403778994858 11.3428777390082 1.8020451573053 0.0726536037709198 46.1771662143427 20.7636155049733 2.22394631625125 0.0269794082039034 HSPB3 other 1 1 1 1.8020451573053 2.22394631625125 0.396734812612082 3.72576849183478 3.03315858330068 1.22834609187509 0.220419341792001 13.5822430355428 20.5976039929759 0.65940888271153 0.510212414030846 KCNAB1 other 1 1 1 1.22834609187509 0.65940888271153 8.08447215880423e-14 101.975037079866 22.2594161903668 4.58120896827464 7.05809501574308e-06 -99.2329331092751 35.8593735893287 -2.76728016071105 0.0060419402465198 MRPL1 other 1.03351892078153e-09 1 0.0734253624487753 4.58120896827464 -2.76728016071105 0.848699886969455 3.34093582212017 31.1319356587096 0.107315390175088 0.91461759796947 60.6039759024868 106.812625796268 0.567385882059314 0.570918306456673 SHE other 1 1 1 0.107315390175088 0.567385882059314 5.49446166941047e-10 460.671688990367 106.696586591191 4.31758600446548 2.21450054593944e-05 -242.803638946207 171.239132384032 -1.41792145034746 0.157362513424993 PGM2 other 6.02192998967388e-06 1 0.220962864473837 4.31758600446548 -1.41792145034746 0.0623559138039788 1.71699628395702 20.3076084888699 0.0845494084100579 0.93268158935162 -70.3849840552771 34.1457250225497 -2.06131174572498 0.0402201321363734 STK32A other 1 1 1 0.0845494084100579 -2.06131174572498 0.0364947870834057 7.73216923977737 3.09005224015607 2.50227783831474 0.0129381463242654 -10.4674001888679 20.1630857880968 -0.519136817592039 0.604095372057041 P2RY12 other 1 1 1 2.50227783831474 -0.519136817592039 0.00228058022388318 8.22368902247148 2.59854335314511 3.16473035268703 0.00172924331660087 -2.3689589460357 7.28016981052571 -0.325398858500615 0.745130307068621 C22orf15 other 1 1 1 3.16473035268703 -0.325398858500615 0.177800978503507 8.57947263754876 4.61501887008185 1.85903305686735 0.0640983702231605 4.61998232304634 8.94300935618647 0.516602648956237 0.605851787690819 KIAA1024 other 1 1 1 1.85903305686735 0.516602648956237 0.915271208490265 11.51239872772 98.2354106923972 0.117191943786631 0.906795077669934 -56.8376942927444 195.877200402491 -0.290170036001911 0.771908888394874 GP2 other 1 1 1 0.117191943786631 -0.290170036001911 2.70756120737783e-12 222.444711543064 28.9602691570401 7.6810305296831 3.09160037382685e-13 56.1408614935699 196.142175861162 0.286225342647921 0.774930011653566 SLC33A1 other 3.28156418334193e-08 1 4.40522137266588e-09 7.6810305296831 0.286225342647921 2.24971490220472e-12 109.511376729285 20.112843141339 5.44484814800752 1.17559759028966e-07 -114.054881614027 39.1681378899498 -2.91193014930875 0.00389548426211046 SNUPN essential 2.73610326406138e-08 1 0.00138461884184316 5.44484814800752 -2.91193014930875 0.000444920886238661 41.8432612478604 13.004289308467 3.21765075009648 0.00144949675164018 -41.458835837998 29.801520597249 -1.39116511530707 0.165316409440869 CRADD other 1 1 1 3.21765075009648 -1.39116511530707 3.12435070591861e-11 515.487439128153 78.7503457335185 6.54584350489709 3.04840459023502e-10 -63.4484672436701 154.084924353567 -0.411775957381006 0.680836505254957 SIN3A essential 3.63361987098335e-07 1 4.00987139799514e-06 6.54584350489709 -0.411775957381006 2.50315440066624e-09 85.8952242703697 17.3716383619598 4.94456668280994 1.45256879962672e-06 -169.509782365059 66.5189826380046 -2.54829186560968 0.0114629005360725 ARL13B other 2.64533357062408e-05 1 0.0159216066127085 4.94456668280994 -2.54829186560968 0.875782285825385 -0.812669412785014 2.21071334555208 -0.367605060339502 0.71345361353232 -2.36585949143076 4.76097246527801 -0.496927782860556 0.619641381249547 RNASE2 other 1 1 1 -0.367605060339502 -0.496927782860556 3.99010296443405e-17 618.276813291513 71.5984881270101 8.63533336339085 5.25523427526569e-16 -448.234031602896 280.599598975563 -1.59741508269914 0.111347202299218 PTK2 other 5.56140551182817e-13 1 7.78615510223364e-12 8.63533336339085 -1.59741508269914 5.30258787292901e-11 54.5431163033671 8.97095681751937 6.07996643087724 4.03718028870961e-09 -58.5139169872248 23.7433893648477 -2.46442982878658 0.0143393979564279 RSPH10B2 other 6.10858122961422e-07 1 5.09855498661137e-05 6.07996643087724 -2.46442982878658 0.0691749245519791 -62.5496837334614 73.4427893257285 -0.851679032178983 0.395144232530165 -242.73926745711 106.984722190805 -2.26891524776957 0.0240599554759047 PTAFR other 1 1 1 -0.851679032178983 -2.26891524776957 1.8821901486008e-09 251.550041955438 46.6432807703882 5.39306064669312 1.53024725459831e-07 -126.69158577868 90.7677171057244 -1.39577803450882 0.16394528486728 PTPN9 other 2.00509716530443e-05 1 0.00178993021370364 5.39306064669312 -1.39577803450882 0.180749126085363 -31.4496232723414 19.0479256296953 -1.65107864676415 0.0998765789861518 -64.0747512270563 41.0486641361248 -1.5609460764563 0.119699184569775 RNASE6 other 1 1 1 -1.65107864676415 -1.5609460764563 0.985502015970288 -4.8296014358406 44.0029103333824 -0.109756409274972 0.912683198745152 18.9227113954263 151.083111663488 0.12524703249145 0.90042016375202 NPR1 other 1 1 1 -0.109756409274972 0.12524703249145 0.233676972643548 3.55461949101475 2.25911914741458 1.5734537485917 0.116776214577832 -2.80088098742104 8.87836775123175 -0.315472513180416 0.752644825137862 KCNK9 other 1 1 1 1.5734537485917 -0.315472513180416 0.207686334873622 -528.570354503781 1019.70074393703 -0.518358310167541 0.604635987680519 -3497.11128862655 2027.17112674143 -1.72511893174404 0.0856588558587529 CXCL8 other 1 1 1 -0.518358310167541 -1.72511893174404 0.000179845548390669 333.718653389326 84.3696979530594 3.95543259589475 9.75996608720861e-05 30.4415001959434 203.366187357104 0.149688109865035 0.881122029572553 SCN9A other 1 1 0.916851214232377 3.95543259589475 0.149688109865035 0.00398138811533529 212.706717780971 75.1236360213667 2.83142202702319 0.00498549563101955 -13.7314640654137 149.346233965043 -0.0919438254373914 0.926811359641992 RASSF6 other 1 1 1 2.83142202702319 -0.0919438254373914 0.691902475992216 -47.9523156410983 57.7548668673094 -0.830273156914511 0.407112501014847 -87.386955314769 223.861915074565 -0.390360974467952 0.696575174004863 COL22A1 other 1 1 1 -0.830273156914511 -0.390360974467952 0.0531553690374309 288.891201660928 127.14280577011 2.27217890867753 0.0238594202017644 -105.893601248364 463.899290050739 -0.228268513273175 0.819609645472838 SDC2 other 1 1 1 2.27217890867753 -0.228268513273175 0.391905795540365 -96.9429657267291 187.816793711545 -0.516157068870087 0.606165598824028 -360.804780365342 270.301971344355 -1.33482112087777 0.183055207286765 CD52 other 1 1 1 -0.516157068870087 -1.33482112087777 0.929966916838235 -141.209193245779 596.016295409404 -0.236921698841777 0.812895870826684 -649.19324577861 2071.68953414882 -0.313364157648911 0.754244172235378 SPRR1B other 1 1 1 -0.236921698841777 -0.313364157648911 0.190650366715012 9.44369598571554 237.261415519232 0.0398029151307582 0.968279451189469 1561.74226998733 855.841383326847 1.82480340447722 0.0691275024601104 SPRR1A other 1 1 1 0.0398029151307582 1.82480340447722 5.84987343336698e-18 271.654178099861 39.167675100488 6.93567278126438 5.9391187385298e-11 -306.943232721218 98.8935320253851 -3.10377459915607 0.0021978672911024 TM2D2 other 8.28342078164764e-14 1 7.99821120517808e-07 6.93567278126438 -3.10377459915607 0.734932620890824 -0.784677313706577 2.16756047900138 -0.362009420871194 0.717741043373841 2.46055047419422 5.43146276175842 0.453018014137619 0.651044639670443 HTRA4 other 1 1 1 -0.362009420871194 0.453018014137619 3.1028045234265e-08 126.50039896626 50.888434912294 2.48583787621457 0.0137743837072509 -492.1348456338 127.515998703589 -3.85939686499861 0.000154936508708812 PLEKHA2 other 0.000307053535638286 1 1 2.48583787621457 -3.85939686499861 9.50109601149523e-05 441.464671709781 312.924803309167 1.41076919132428 0.159455339718946 -1169.13913598306 460.635697292291 -2.5380992894287 0.0117039270041074 CLIC4 other 0.706026444614211 1 1 1.41076919132428 -2.5380992894287 0.0196335004285563 140.450820820875 145.337057302404 0.966379968246072 0.334718875070567 993.337073988462 352.012058809356 2.82188365179398 0.00512902054025798 SLC38A11 other 1 1 1 0.966379968246072 2.82188365179398 0.811047133090809 -15.1049417400502 34.2369544609997 -0.441188241706974 0.659428504587979 13.9501248510763 61.768099643183 0.225846754743342 0.821490844972572 GPR183 other 1 1 1 -0.441188241706974 0.225846754743342 0.571682212473811 -1.53810481879481 14.1777818848541 -0.108486985572683 0.913689389321025 -56.6526783501687 53.5272441479185 -1.05838959677456 0.290816873735246 CRCT1 other 1 1 1 -0.108486985572683 -1.05838959677456 0.0883325637637395 55.3255151335255 56.0522458820418 0.987034761282435 0.32450602221833 -195.194030327163 138.751249777257 -1.406791150642 0.160635075317876 CCDC8 other 1 1 1 0.987034761282435 -1.406791150642 4.88915802568169e-21 81.2831879252395 9.65424934586705 8.41942081805009 2.40646254133489e-15 -30.5383768651646 18.2475804882725 -1.67355759218551 0.0953975017590009 METTL15 other 7.24279869924486e-17 1 3.53629670449163e-11 8.41942081805009 -1.67355759218551 7.46123642740232e-11 14.8662784859295 2.10323944934745 7.06827674354524 1.31154109002889e-11 8.48814325425156 7.21366114339609 1.17667618224932 0.240349724253754 ZNF280A other 8.53789284387648e-07 1 1.79877860497463e-07 7.06827674354524 1.17667618224932 0.060626085129578 109.608877251422 59.8869411133512 1.8302634132533 0.0683169831055897 -55.0222875545274 115.358548973285 -0.476967576692295 0.633772459975684 MUC15 other 1 1 1 1.8302634132533 -0.476967576692295 0.127973338200005 -170.877590361789 85.8133668592229 -1.99127008548813 0.0474663079330952 -69.4244980455281 199.168846520692 -0.348571070517875 0.727685020497157 ZEB2 other 1 1 1 -1.99127008548813 -0.348571070517875 4.89322743709389e-14 1559.38777971234 188.988096905696 8.25124865133947 6.81105444421788e-15 1122.76980863277 873.245694851578 1.28574330827202 0.199626185229599 PCBP1 essential 6.30003032525838e-10 1 9.94890722666906e-11 8.25124865133947 1.28574330827202 9.25374686103693e-11 1410.35454171715 285.057806329749 4.94760890738659 1.31816392524076e-06 -932.361550473151 466.080662968988 -2.00042959202362 0.0464477915386057 HINT1 other 1.05464952975238e-06 1 0.0144918941940969 4.94760890738659 -2.00042959202362 2.71710165073315e-10 27.7839704069048 9.95242048059141 2.79167971862598 0.00561516298383239 -69.2789687254794 16.3924932571999 -4.22626184061725 3.24656553783159e-05 DTWD2 other 3.02685123891673e-06 0.492763717332078 1 2.79167971862598 -4.22626184061725 0.468998368439296 -7.84657682193293 32.5719024850721 -0.240900169264877 0.809815317844264 63.0450818206807 61.3197176420907 1.02813718400761 0.304805469116564 CLIC3 other 1 1 1 -0.240900169264877 1.02813718400761 8.76567072038677e-14 161.594130734188 39.0066796183946 4.14272971488668 4.60968215493656e-05 -321.612968092514 77.9097380994905 -4.12802014148496 4.89562679259308e-05 INO80E other 1.119639121115e-09 0.739190689413629 0.446539910348705 4.14272971488668 -4.12802014148496 0.512145372655997 109.497515978239 100.806322065773 1.08621675440947 0.278351910256031 0.44676079001692 196.328521946403 0.00227557761647534 0.998186033698105 BNC1 other 1 1 1 1.08621675440947 0.00227557761647534 1.83525383844763e-08 31.5679153139939 9.0295288125446 3.4960755947904 0.00055242206827514 -32.5627172298047 14.1957149318445 -2.29384130254395 0.0225735689269924 DFFB other 0.000184020902381144 1 1 3.4960755947904 -2.29384130254395 4.20634343245719e-07 137.781204017462 24.7508182517956 5.56673329405851 6.23929652699656e-08 4.25216594926285 119.770551200979 0.0355025998179433 0.971705109552196 NFU1 other 0.00386520898008491 1 0.000745533542010819 5.56673329405851 0.0355025998179433 0.0366362845990149 -134.912951891206 231.39882463929 -0.583032139862901 0.560360109455916 2903.4925497971 1163.90801351831 2.49460654628565 0.0132099933986825 ANTXR1 other 1 1 1 -0.583032139862901 2.49460654628565 1.49330240316644e-08 165.278969727407 27.6889518131031 5.96913060642451 7.41942512692128e-09 -11.5885084346672 87.7356235348637 -0.13208441414977 0.895015175989912 CKAP2L other 0.000150375551998861 1 9.26166838593584e-05 5.96913060642451 -0.13208441414977 3.33685662150323e-15 140.072646934179 22.3104300655059 6.27834813237173 1.35981085925582e-09 -149.768175178713 43.4513795264889 -3.44679908465073 0.000657735097900622 C15orf40 other 4.4366845639507e-11 1 1.74912470826076e-05 6.27834813237173 -3.44679908465073 6.59243499727557e-11 76.5026247120048 14.2796695179189 5.3574506480003 1.8093181346079e-07 -71.6110616089885 27.8108193304278 -2.57493534290228 0.010558820042928 FAM103A1 other 7.56086369837535e-07 1 0.00210640817231051 5.3574506480003 -2.57493534290228 6.41917747600144e-05 48.9930109674049 11.4716187054709 4.27080190034906 2.69149464957524e-05 -7.2213244856789 36.3664303050114 -0.198571166460728 0.842746005804541 RGPD8 other 0.486766228005189 1 0.266754034719402 4.27080190034906 -0.198571166460728 4.63337810530264e-10 115.091175703566 18.0093844714959 6.39062239388163 7.39951765022448e-10 -32.1407192434789 63.4124870839871 -0.50685157957785 0.612680439725629 HIC2 other 5.09949594269608e-06 1 9.6053138617564e-06 6.39062239388163 -0.50685157957785 7.16237819160304e-08 159.838882364188 69.8444500645587 2.2884979725153 0.0228755724710377 -316.805787171612 103.290204936781 -3.06714259464887 0.00237899398854143 LUZP1 other 0.000692458723564182 1 1 2.2884979725153 -3.06714259464887 0.0234942759264669 37.9143340024454 25.7520352599677 1.47228495222606 0.14214415451632 -91.4387318072908 56.0899647310707 -1.63021553402117 0.104257521671558 HEXDC other 1 1 1 1.47228495222606 -1.63021553402117 1.63229585352578e-07 269.365480018744 48.557968244408 5.54729717402797 6.87439609824605e-08 -10.5930395531354 157.325231093772 -0.0673321086483675 0.946366782495998 BUB1 other 0.00154039759697228 1 0.000819221783027982 5.54729717402797 -0.0673321086483675 1.97185746793867e-13 261.540568287191 53.2031086194717 4.91588884698121 1.55426231644484e-06 -335.859116273679 107.226166478756 -3.13224959264231 0.00193004120332399 SPNS1 other 2.49065316775334e-09 1 0.0170160638404381 4.91588884698121 -3.13224959264231 2.72524557235209e-07 122.634754929886 25.797603724943 4.75372659559513 3.27434269753816e-06 -64.450818644296 57.9639035529539 -1.11191301299119 0.267179489714804 LRRC45 other 0.00253665857874532 1 0.0349339622400346 4.75372659559513 -1.11191301299119 3.0182730879054e-07 64.8546338393135 12.5802578545933 5.15527063029427 4.86807020577379e-07 -7.99547697643754 24.3780939718824 -0.327977937309598 0.743179739689171 CHRNA5 other 0.00280367387135532 1 0.00550578740273015 5.15527063029427 -0.327977937309598 1.4606759402122e-06 286.926548722539 61.9453125720863 4.6319331812014 5.67457001793294e-06 -101.821145570535 139.1831645206 -0.731562225368603 0.465079796421653 CENPX other 0.0128349594866446 1 0.0594411209378475 4.6319331812014 -0.731562225368603 6.66998588501774e-05 220.547216974809 74.8041770533383 2.9483275622102 0.00347348626153751 -280.326372621905 140.362458659828 -1.99716060332972 0.0468075599660737 AGPAT2 other 0.504517732342742 1 1 2.9483275622102 -1.99716060332972 0.00685270191096067 269.72746236877 113.067014713122 2.38555393943258 0.0177537047908141 -277.15236724227 254.047065988346 -1.09094890021278 0.27628257752933 ASPSCR1 other 1 1 1 2.38555393943258 -1.09094890021278 9.45646340217364e-10 2647.94972609624 403.891325521583 6.55609456993585 2.87353224559564e-10 979.679876901042 908.201072200182 1.07870372199374 0.281700697459231 FASN other 1.0228110815791e-05 1 3.78214314165298e-06 6.55609456993585 1.07870372199374 1.26845214936104e-20 2189.83687002932 220.68668996644 9.92283164137507 5.36377878047618e-20 -1238.02837836982 842.8623837766 -1.46883809528028 0.143036525810395 CNBP other 1.86868370643868e-16 1 8.21409082442122e-16 9.92283164137507 -1.46883809528028 0.314092646767763 94.7648776155042 143.78777324879 0.659060749564127 0.51041430973806 -184.869949182405 258.293416681555 -0.715736202484509 0.47476822295263 MT1E other 1 1 1 0.659060749564127 -0.715736202484509 1.15145541684678e-12 675.549495708749 91.2402287233288 7.40407499149573 1.75945023053984e-12 77.3456295106592 205.165271740626 0.376991821542007 0.706481390628874 DUS1L other 1.41536899838807e-08 1 2.46551760805548e-08 7.40407499149573 0.376991821542007 1.26838650180435e-23 821.031427038677 77.1095504691691 10.6475971140171 2.76266254042898e-22 31.1285648562597 173.255260219578 0.179668800917262 0.85754937654552 GPS1 essential 1.92452283918774e-19 1 4.27245761877342e-18 10.6475971140171 0.179668800917262 3.222939733213e-10 190.051423949456 31.7468537892256 5.98646483872856 6.91646236111396e-09 -70.1130892569758 71.3311046548555 -0.982924484293728 0.326537777233657 RFNG other 3.57689140576873e-06 1 8.64350301268412e-05 5.98646483872856 -0.982924484293728 4.24115931583142e-13 388.980224815767 52.1418545966164 7.46003815600776 1.22876497401812e-12 14.3765057889731 117.156053063494 0.122712445606046 0.902427470037457 DCXR other 5.29593563767869e-09 1 1.72788930646429e-08 7.46003815600776 0.122712445606046 6.13387637149024e-05 72.9527205600389 44.6163295305167 1.63511255470131 0.103203805011677 -170.050646672094 71.3072056788441 -2.3847610497875 0.0177885443944884 ZNF32 other 0.465929249178399 1 1 1.63511255470131 -2.3847610497875 0.0762287499252119 -38.2082404674416 87.353714217269 -0.437396861825576 0.662175821551117 -251.968951956423 128.508002756886 -1.96072576455104 0.0509466648310174 LDB2 other 1 1 1 -0.437396861825576 -1.96072576455104 5.03864215960048e-10 240.318734813392 35.9719454916623 6.68072664763417 1.38582588077598e-10 96.4503025280153 80.8243432732019 1.19333233803082 0.23380248793932 RAC3 other 5.53646000496901e-06 1 1.84467282990091e-06 6.68072664763417 1.19333233803082 0.0208507920208523 27.2514904662918 13.8965009789761 1.96103252952095 0.050910670103523 -28.9995014192405 27.1982209352755 -1.06622787895766 0.287280229156845 NRG4 other 1 1 1 1.96103252952095 -1.06622787895766 3.94412857809716e-05 326.685528645182 71.2041598672984 4.58801184163985 6.84809014736591e-06 255.938592442233 248.587028686158 1.02957340049049 0.304128323704405 LIMS1 other 0.305236110658939 1 0.071268074163637 4.58801184163985 1.02957340049049 0.00127738464961294 10.681897857928 2.92984625810937 3.64589023344217 0.000319830875177314 5.0198919788956 5.73194618227623 0.875774443664113 0.381934002492626 TMEM266 other 1 1 1 3.64589023344217 0.875774443664113 6.01388824966976e-08 22.4284505103894 3.82393234679083 5.8652843398791 1.34195455059911e-08 46.3041922313107 39.8819528478498 1.1610312164994 0.246681915064385 NLGN1 other 0.000583948549042934 1 0.000165650869725955 5.8652843398791 1.1610312164994 1.90113122220988e-09 53.366634540088 44.4388102470826 1.20090151476527 0.230849707490044 -263.422323956388 65.3749276824209 -4.02940903026377 7.28985286528445e-05 TAPT1 other 2.02470475165353e-05 1 1 1.20090151476527 -4.02940903026377 8.8557639913549e-23 793.961238741542 71.3494963709867 11.1277763561677 7.96433912743205e-24 371.662993400574 446.547841225894 0.832302743599115 0.405993191142074 UGP2 other 1.33438651821736e-18 1 1.24036617570627e-19 11.1277763561677 0.832302743599115 0.00115468895888896 152.808268728891 42.9751543267529 3.55573519450435 0.000444402003100862 22.7813599031454 84.0681926583465 0.27098667382715 0.786606812294186 LINGO1 other 1 1 1 3.55573519450435 0.27098667382715 9.72523470690775e-20 1261.73451029939 236.459094596544 5.3359525564124 2.05232301277085e-07 -1448.75694040573 377.964384554808 -3.83305147153526 0.000158407882842272 HNRNPF other 1.41618867801991e-15 1 0.00238172085632057 5.3359525564124 -3.83305147153526 0.000611625986834526 33.7545855838565 17.5106596221273 1.92765928367442 0.0549348380764781 -120.942134135753 47.8972639139399 -2.52503220962803 0.0121354965303636 BTD other 1 1 1 1.92765928367442 -2.52503220962803 0.00029306516329137 21.2095634326851 45.1660770485768 0.469590560408289 0.63904114969646 -215.322061916124 71.3529583770026 -3.01770335545784 0.00279981701290859 CSGALNACT2 other 1 1 1 0.469590560408289 -3.01770335545784 0.130911814560047 157.143638542998 187.38556534405 0.838611225226844 0.40244046955937 -226.12813674136 270.25779168089 -0.836712737623356 0.403505104804166 PCDH7 other 1 1 1 0.838611225226844 -0.836712737623356 0.598390768140138 29.1591551384455 370.408213329742 0.0787216754086596 0.937314094384183 -717.905514480003 804.63675680497 -0.892210688125462 0.373098710949421 ROBO1 other 1 1 1 0.0787216754086596 -0.892210688125462 9.98303757232669e-09 81.4530021184182 17.3781040941246 4.68710520303288 4.41471328974343e-06 -37.735464691054 30.9537551008432 -1.21909166006247 0.223881314161736 AVEN other 0.000101767085012298 1 0.0466458606194291 4.68710520303288 -1.21909166006247 0.00103072473871443 239.034823600973 64.5904978358 3.70077382293352 0.000260668367313525 -141.503744906634 413.63117807494 -0.34210125446829 0.732541817365513 P2RY1 other 1 1 1 3.70077382293352 -0.34210125446829 0.517451218182444 -1.57981415974453 6.93350073089442 -0.227852310263006 0.819936102176884 -49.862076781124 43.5316829365202 -1.14542037930937 0.253064539313248 CTNND2 other 1 1 1 -0.227852310263006 -1.14542037930937 1.6973204053105e-07 253.594195619383 55.9959832006015 4.52879262269402 8.88456580097125e-06 -551.368276071831 242.460316604666 -2.2740557456701 0.023741870330847 TRIM56 other 0.00160091260628887 1 0.0915909888422126 4.52879262269402 -2.2740557456701 0.451705594197493 0.0299222999799527 20.60953703535 0.00145186667360015 0.998842642639442 -61.0860488760585 51.3879627603403 -1.18872291476016 0.235585503481553 WNT10B other 1 1 1 0.00145186667360015 -1.18872291476016 0.806428226813361 2.90555169849426 7.13475223361099 0.407239327079438 0.684156091760498 -2.50938775174186 11.3948234901363 -0.220221730851211 0.825865510872242 CALML6 other 1 1 1 0.407239327079438 -0.220221730851211 0.349529413314148 -16.3981666744218 15.151672879511 -1.08226773405308 0.280088594702694 -78.2851309850639 64.7559049047655 -1.20892652338339 0.227737066271912 MUC3A other 1 1 1 -1.08226773405308 -1.20892652338339 0.0512469603616995 -171.448934966096 70.0690045017574 -2.4468584388379 0.0150632486572624 -153.228328191353 143.762973146062 -1.06584000621408 0.287469755870858 ITGAM other 1 1 1 -2.4468584388379 -1.06584000621408 0.312486199319121 48.1814716172026 38.0020107611567 1.26786637475643 0.206002106325659 -46.7648583346494 113.201110485755 -0.413113070481177 0.679870938390971 TPST1 other 1 1 1 1.26786637475643 -0.413113070481177 3.22924332443649e-08 243.06898624759 45.8395403478584 5.30260522690747 2.38379516991295e-07 -335.549851033549 138.756693615521 -2.41826064235372 0.0162594186880864 TOR1AIP2 other 0.000318952363154592 1 0.00275542883690238 5.30260522690747 -2.41826064235372 2.67496508601825e-06 2323.569917076 447.903632058873 5.1876558946291 4.20626910255577e-07 1065.22979075834 2836.40882637116 0.375555801707603 0.707544229714917 TM4SF1 other 0.0229645752634667 1 0.00478252796960591 5.1876558946291 0.375555801707603 2.83411718274787e-12 201.199560096065 32.4036605407694 6.20916145701877 1.97519810340309e-09 3.43951489307243 47.5182682483689 0.0723830017351378 0.942350113104577 OTUD3 other 3.4306988497163e-08 1 2.52450069595949e-05 6.20916145701877 0.0723830017351378 0.852285221477653 1.52718848426474 5.08443920932523 0.300365177237986 0.764129761161617 -2.28212510086684 9.3677388975977 -0.243615361808609 0.807713725307735 OTUD7A other 1 1 1 0.300365177237986 -0.243615361808609 1.06023520708943e-06 112.311056716997 52.3374863998845 2.14590085314539 0.0328288056214905 -640.424153618154 157.550258392625 -4.06488799289797 6.41240097154902e-05 GUSB other 0.0094201898149896 0.963719742014102 1 2.14590085314539 -4.06488799289797 3.57928105870651e-15 340.943166720792 58.7285527297975 5.80540726568604 1.77932709848473e-08 -408.389156210328 110.733623777669 -3.68803207443378 0.000272666058436749 BRD3 other 4.7550748864916e-11 1 0.000218252261900137 5.80540726568604 -3.68803207443378 0.030235613780211 329.763263331439 181.841824141505 1.81346213880271 0.0708666716236384 -225.060350682718 335.426816803447 -0.670967076596617 0.502812962062521 KLF13 other 1 1 1 1.81346213880271 -0.670967076596617 0.00165081531351108 32.083719269141 8.86465286179671 3.61928659467419 0.000352633284366717 21.1167791832753 36.2612093118654 0.582351763330891 0.560815740012449 ZFPM2 other 1 1 1 3.61928659467419 0.582351763330891 4.3029806259265e-12 47.8539088358039 10.2057011213324 4.68893888493142 4.38559264622378e-06 -62.0774032234853 20.7528835064031 -2.99126640422435 0.003037850124109 ZNF764 other 5.17132211623847e-08 1 0.0463513286779392 4.68893888493142 -2.99126640422435 3.20471845599604e-14 61.5158768347966 12.7182762555538 4.83680929700942 2.23188389227801e-06 -94.5162088669832 25.8621041705854 -3.65462176795663 0.000310055084383675 ZNF747 other 4.14882851313247e-10 1 0.0241199692238485 4.83680929700942 -3.65462176795663 1.74766048138081e-12 310.96151989185 55.1798820951335 5.63541472154169 4.44511234946761e-08 -217.965012231234 112.248410624364 -1.94180934071885 0.053215916539762 ZNF768 other 2.13511681010294e-08 1 0.000535235977999395 5.63541472154169 -1.94180934071885 0.0189863569257077 -15.0044788273617 11.0606142995185 -1.35656830814677 0.176081734189421 -49.1199395067475 17.3744348127138 -2.82713884142027 0.00505753148588922 TAS1R3 other 1 1 1 -1.35656830814677 -2.82713884142027 7.20108634436213e-05 146.098970901526 49.9043348800783 2.92758076533044 0.00370610580810432 -296.300622148901 135.043845495276 -2.19410681813904 0.0290767774207895 MAP3K2 other 0.542169790867025 1 1 2.92758076533044 -2.19410681813904 1.56656149284416e-14 105.986970684038 24.4007980554541 4.3435862402192 2.00311194055206e-05 -141.662226617032 38.3297042743039 -3.695886240166 0.000266613563838308 PUSL1 other 2.04310949896735e-10 1 0.200551567488072 4.3435862402192 -3.695886240166 5.38254497946684e-11 543.422573652308 90.5619903340133 6.00055908276796 6.23141860959077e-09 -271.579680206212 159.792532161784 -1.69957679831525 0.0903496016301738 SF3B5 essential 6.19907705285196e-07 1 7.80485180851243e-05 6.00055908276796 -1.69957679831525 1.16100093536327e-07 43.1536078824711 8.87351754383857 4.86319068726418 1.95678575642321e-06 -32.556717210455 23.2975607111185 -1.39743029813922 0.163423001842819 ZNF35 other 0.00110724659205596 1 0.0212585204577817 4.86319068726418 -1.39743029813922 0.0140366526868447 481.377401025781 213.874638194274 2.25074560074074 0.0252034662878231 -69.5549551844069 323.629031025303 -0.214921865829054 0.829989882443184 IFFO2 other 1 1 1 2.25074560074074 -0.214921865829054 1.74404635830916e-07 321.677757232469 56.369524080402 5.70658990793762 3.00758121897733e-08 169.258471038917 164.090237886962 1.0314962865464 0.303224446080216 NLGN2 other 0.00164411250197805 1 0.000364729374425381 5.70658990793762 1.0314962865464 0.75415117731736 4.18950595623175 9.75950960436289 0.429274228528745 0.66806474394448 -11.6474722394533 26.4097640072421 -0.441029016247905 0.659543626877223 MYO7B other 1 1 1 0.429274228528745 -0.441029016247905 0.000119830287532657 958.088485779472 235.629581665241 4.06607896601298 6.25947009798326e-05 -180.553597111474 695.175145302035 -0.259723895958662 0.795272517587953 CHD3 other 0.878356007614372 1 0.599594640685817 4.06607896601298 -0.259723895958662 0.0114597333360758 24.431632010082 85.7386634323515 0.284954663765651 0.775896519261053 -285.835556255689 127.145818094347 -2.2480924700456 0.0253743390125928 TMEM154 other 1 1 1 0.284954663765651 -2.2480924700456 0.55931665045322 6.24117907112897 6.44522015589094 0.968342262975227 0.33373055027258 -0.42528048940758 17.1278642668019 -0.0248297442566661 0.980208905309452 MYRIP other 1 1 1 0.968342262975227 -0.0248297442566661 0.000134909040461844 1069.89129406074 274.777077517482 3.89367011152039 0.000124927511069644 -943.357443472329 1043.94274249976 -0.903648643807249 0.366999365708583 ALCAM other 0.983756723047768 1 1 3.89367011152039 -0.903648643807249 6.62803713311447e-19 2202.45621755658 252.382919863167 8.72664528467563 2.76594177381003e-16 -1532.4783679364 842.077906644041 -1.8198771822002 0.0698849512426243 YWHAG other 9.54172225683159e-15 1 4.11295541765552e-12 8.72664528467563 -1.8198771822002 1.84743567961505e-08 262.05338740985 49.9895305920073 5.24216539556284 3.19731290171966e-07 -174.066572506194 133.657440387254 -1.30233357755364 0.193908100412114 UBE2E3 other 0.000185186952524613 1 0.00366699816698228 5.24216539556284 -1.30233357755364 9.89012961005126e-15 302.500530869496 36.7123180272939 8.23975567668053 7.26866044203977e-15 21.8238529830353 108.311914143518 0.20149078848443 0.840464880871357 CNTROB other 1.29748610354262e-10 1 1.06115173793339e-10 8.23975567668053 0.20149078848443 9.63775977753809e-16 391.320012650506 52.817871869565 7.40885610872169 1.59640479164899e-12 -405.115545063667 155.827937612833 -2.59976196354603 0.00983654029223408 TRAPPC1 essential 1.29868813002326e-11 1 2.23879807980855e-08 7.40885610872169 -2.59976196354603 0.721449426130516 102.879380838105 148.233617325185 0.694035419863056 0.488267943603815 -123.119665152876 548.088255978878 -0.224634744148981 0.822436542792075 ZPLD1 other 1 1 1 0.694035419863056 -0.224634744148981 0.0884169059115791 11.2754647931868 5.10634141454297 2.20812982874079 0.0280665146995833 11.3395719911747 15.0651781908263 0.752700820895682 0.452278261972941 KCNAB3 other 1 1 1 2.20812982874079 0.752700820895682 0.00208650619274166 12.2770116774663 13.4104903300824 0.915478209616729 0.360748559927094 -59.8627693267266 22.6314892164224 -2.6451095972636 0.00863967181062237 FAM153A other 1 1 1 0.915478209616729 -2.6451095972636 0.451048806453692 9.72556154963611 8.66678433232076 1.12216494338816 0.262778305380164 16.3648156394402 23.6890827358577 0.690816770827059 0.490267643143725 GPR37L1 other 1 1 1 1.12216494338816 0.690816770827059 2.77493530657815e-06 71.8675595987564 19.3105178805604 3.72167955532174 0.00024030399601206 -47.6857702618502 32.1087658107755 -1.48513245706402 0.138662513861973 SIMC1 other 0.0238006201245208 1 1 3.72167955532174 -1.48513245706402 2.88231009035073e-14 94.0319266633073 27.0188642155098 3.48023240034382 0.000583656480250585 -156.67754432592 39.2469610658241 -3.99209365696223 8.43859458031066e-05 TMEM192 other 3.73605033911261e-10 1 1 3.48023240034382 -3.99209365696223 0.00808422707100822 2.45521142660811 1.12087992595498 2.19043215045205 0.0293481504866868 -5.18605459706643 3.5681763189563 -1.45341881496018 0.147268799070221 SPDYE5 other 1 1 1 2.19043215045205 -1.45341881496018 4.44737479589805e-05 22.0887117696767 14.8983166783059 1.48263137686159 0.139347310101891 -65.678487242969 24.5656959934423 -2.67358544453622 0.00796523127241068 ZNF778 other 0.342269964292314 1 1 1.48263137686159 -2.67358544453622 1.22478673976713e-10 229.288127144239 43.2177335832945 5.30541766384687 2.40099644507746e-07 -140.588844415774 90.6799139624655 -1.55038572791288 0.122260651747934 NIPA1 other 1.38719346146025e-06 1 0.00277483159157603 5.30541766384687 -1.55038572791288 6.59483627429889e-08 360.67777745667 67.697014033744 5.32782402007994 2.09757893249647e-07 -133.953258097377 182.340992528432 -0.734630519664906 0.463202087834965 UBE2E1 other 0.000638841789891334 1 0.00243361107748241 5.32782402007994 -0.734630519664906 0.000484362098930464 144.302910381719 77.7945362997776 1.85492345922154 0.0646971731344774 -273.672473509594 139.320241868207 -1.96434107377219 0.0505161518689081 SIK2 other 1 1 1 1.85492345922154 -1.96434107377219 0.0742658794425324 87.9835703027652 67.7452834205637 1.29874089914957 0.195136857554525 -69.3677991137373 100.650330499455 -0.689195939740239 0.491289627850666 RNF150 other 1 1 1 1.29874089914957 -0.689195939740239 0.620688150614135 16.1126708661556 18.1183549914579 0.889300980897661 0.374624286564694 34.497084491228 47.1067574596552 0.732317110146525 0.464603274761869 CCDC144A other 1 1 1 0.889300980897661 0.732317110146525 0.0842236301518591 4.46059286945234 5.27883753770352 0.844995292541785 0.398870009478246 -25.8289653320203 15.233828795349 -1.69550056515707 0.0911462305494186 HOXD4 other 1 1 1 0.844995292541785 -1.69550056515707 0.00269247917624527 49.6853290890365 19.993280301773 2.48510141102911 0.0135528969336933 -93.9352120587964 58.1999258354436 -1.61400913678811 0.107684904158914 CHRNB1 other 1 1 1 2.48510141102911 -1.61400913678811 5.38271405572962e-19 130.255038350277 35.1959125799177 3.70085696895948 0.000260587126550286 -238.265110382916 51.4381369653147 -4.63207115264655 5.64413630209589e-06 USP38 other 7.75864403992867e-15 0.0872414148214961 1 3.70085696895948 -4.63207115264655 0.573408223345379 15.9315277350467 28.2360627797703 0.564226247097767 0.573065113863829 63.9247848568805 63.6889152308962 1.0037034643333 0.316413630283365 SLC16A5 other 1 1 1 0.564226247097767 1.0037034643333 1.36615003671233e-12 53.2330110784321 9.04114950369606 5.88785873485116 1.20861791125274e-08 -93.1296242250105 30.0567135061089 -3.098463316892 0.00215958892460358 NANP other 1.67489994500931e-08 1 0.000149554380338415 5.88785873485116 -3.098463316892 0.0107689882981835 4.50744524384992 5.24609366384703 0.859200298864766 0.390983823806634 -18.5856491109737 9.273653942299 -2.00413442496499 0.0460433663690452 ANKK1 other 1 1 1 0.859200298864766 -2.00413442496499 0.670917295409296 5.2162849872774 6.05545039419787 0.861419819783425 0.38976283071498 2.04099519366699 9.89136993026052 0.206341003122631 0.836678352882667 ADRA1B other 1 1 1 0.861419819783425 0.206341003122631 2.4943424919549e-09 23.331379052602 4.47139404799994 5.21792058631874 3.6103454126445e-07 -25.5443216855091 13.3296155347177 -1.91635847402931 0.0563751829117218 ADPRM other 2.63701888249472e-05 1 0.00412481963394634 5.21792058631874 -1.91635847402931 0.00342380618738561 3.79435577145476 30.6236315025351 0.12390286799071 0.901483357974609 -146.050193409927 50.0226487017039 -2.919681328369 0.00379615732231765 FABP6 other 1 1 1 0.12390286799071 -2.919681328369 4.82003756284168e-12 70.2967846402965 14.4903751578199 4.8512743027471 2.0643926943973e-06 -65.1982773022848 23.669529396457 -2.75452359910646 0.00627280917482095 PWWP2A other 5.77777902657832e-08 1 0.0223800811999612 4.8512743027471 -2.75452359910646 7.49636942288358e-09 5.45428552186079 1.579065006976 3.45412348305156 0.000640525095221211 -9.99690884656126 3.01309595160927 -3.31781961381681 0.00103135676847095 USP50 other 7.69652248647458e-05 1 1 3.45412348305156 -3.31781961381681 1.15535487725172e-19 362.170268267517 73.3478812693712 4.937705929602 1.39197139875331e-06 -495.308831656967 114.950351488395 -4.3088935809559 2.30580852083736e-05 USP47 other 1.68092581091353e-15 0.351566625172073 0.0152782780727163 4.937705929602 -4.3088935809559 9.38238565775673e-17 693.467670737121 83.5681687892318 8.29822743257811 5.0944444655826e-15 -439.544462821353 274.640038390435 -1.60043839710103 0.110670753946976 PDCD6IP other 1.29533216390989e-12 1 7.45571947538013e-11 8.29822743257811 -1.60043839710103 1.40566686917862e-16 105.878940572376 14.7204307882134 7.19265231403101 6.21516648353669e-12 -89.6399323175036 37.9635610390134 -2.36120979866416 0.0189234029680297 ZNF212 other 1.93279194512061e-12 1 8.59184614684113e-08 7.19265231403101 -2.36120979866416 2.2050947239773e-10 11.9284962955712 6.26403483179405 1.90428320018694 0.057944086845807 -43.5182222074104 8.98444631495098 -4.84372889345356 2.15755488983417e-06 MRAP other 2.46860354349259e-06 0.0336017598542773 1 1.90428320018694 -4.84372889345356 1.62505657788004e-08 48.3314419624622 7.79914367275233 6.197019056248 2.24277825776496e-09 17.5223907294735 49.210761896224 0.356068267474192 0.722078188106852 FAM161A other 0.000163415689471617 1 2.85954227865033e-05 6.197019056248 0.356068267474192 1.53482363910985e-21 268.270551187255 30.8303247532476 8.7015155803377 3.24146812695284e-16 -184.650063378334 79.5105070267156 -2.32233537784247 0.0209559812033829 ZNF282 other 2.28458498681502e-17 1 4.81487675577575e-12 8.7015155803377 -2.32233537784247 9.62327148606806e-16 474.274386639079 56.3290252792183 8.41971584432963 2.27793365941825e-15 -78.3899601815309 185.017191551349 -0.423690142111873 0.672130386838511 GLB1 other 1.29683206546253e-11 1 3.34856247934483e-11 8.41971584432963 -0.423690142111873 2.89082145189477e-08 70.9968659480992 13.9961511812104 5.07259924738533 7.27433254818964e-07 -20.6028008083368 28.1337976314299 -0.7323149572001 0.464606894401697 GON7 other 0.000286711671598923 1 0.00814216042118867 5.07259924738533 -0.7323149572001 0.0136561289976795 -11.7822351457515 90.8490448412187 -0.129690247886963 0.896907000841469 -402.383194235822 151.571869341963 -2.65473531455893 0.00840312128216257 FAXDC2 other 1 1 1 -0.129690247886963 -2.65473531455893 3.12973431457377e-18 1602.66235589713 167.247931351021 9.58255413356031 6.67548880717763e-19 654.878498606066 549.33921540366 1.19212042439907 0.234264626301528 CRTAP other 4.45329895620702e-14 1 1.01534184757172e-14 9.58255413356031 1.19212042439907 0.559358497960119 -7.44824777619915 10.7034115595601 -0.695876051738523 0.487102794321017 -20.2952971629303 18.9747447987338 -1.06959526350439 0.285753273292498 HSPB2 other 1 1 1 -0.695876051738523 -1.06959526350439 0.21233739948927 3.13321115723738 1.96623918733503 1.59350458348051 0.112225712071121 -1.54456018422905 6.6863809805465 -0.231000923926236 0.817490337653925 CNGB3 other 1 1 1 1.59350458348051 -0.231000923926236 1.43472936596281e-20 295.510004079257 29.3949818871277 10.0530765834104 2.05347939133898e-20 4.17096638771831 87.947007162473 0.0474259047839215 0.96220871430274 ELP5 essential 2.11206509963386e-16 1 3.14921599455745e-16 10.0530765834104 0.0474259047839215 1.91226802786165e-05 64.7087932125501 14.0796290461798 4.59591605718528 6.62162304543418e-06 3.35054796317333 46.2755013983455 0.0724043578551722 0.942333722497594 CMTM8 other 0.152916259428048 1 0.0690171770025605 4.59591605718528 0.0724043578551722 2.32452217016466e-05 621.260121902439 178.33435792111 3.48368160316738 0.000576507409549693 -1130.26956755922 533.559541340321 -2.1183569592251 0.0350549769017634 GABARAP other 0.184241627207251 1 1 3.48368160316738 -2.1183569592251 0.0129041998361528 15.2645090640421 9.14988566627277 1.66827320261588 0.0964164541035443 -25.8261788532074 22.6241579819287 -1.1415310516235 0.254656668204088 LGALS9B other 1 1 1 1.66827320261588 -1.1415310516235 2.10336348884876e-11 105.255401914375 18.6154521485696 5.65419529293909 3.95485880120369e-08 -142.142290232503 56.2742569524533 -2.52588479937818 0.0121088728555843 STX8 other 2.46345931813967e-07 1 0.000476955971425165 5.65419529293909 -2.52588479937818 6.68388832215057e-10 706.128540244808 120.402490860267 5.86473365459114 1.31584199457184e-08 146.627128752083 180.568247247753 0.812031633396205 0.417491473496582 CDK1 essential 7.2934589371307e-06 1 0.000162545961589459 5.86473365459114 0.812031633396205 8.66569933475293e-06 2328.25225364566 670.279739920164 3.47355307788802 0.000597091528434103 -3157.60901108072 1727.72868522556 -1.8276069837137 0.0687000204730647 UBB other 0.0713620340216904 1 1 3.47355307788802 -1.8276069837137 1.42918693626877e-13 257.861960568881 45.6551031416456 5.64804244924955 4.10961442156637e-08 -177.986785082098 83.3451604315106 -2.13553833432668 0.0336169348547185 NFRKB other 1.81292362865694e-09 1 0.000495331826231395 5.64804244924955 -2.13553833432668 0.490493084092459 -192.779125231082 199.018685303201 -0.968648370565743 0.333590762834037 -644.71163023945 642.263015561661 -1.00381247965158 0.316371108425317 FABP4 other 1 1 1 -0.968648370565743 -1.00381247965158 0.00403763293209655 27.2181248912855 10.3471638928041 2.63049132818068 0.00901581337054211 -8.22592675964099 18.98078383833 -0.43338182604606 0.66508343407775 PRDM10 essential 1 1 1 2.63049132818068 -0.43338182604606 1.70516372755342e-10 261.141738340215 37.2812467767858 7.00464069519324 2.08450456972434e-11 56.8815523009847 235.519215116626 0.241515547989652 0.809344480349287 B3GNT2 other 1.91796816075209e-06 1 2.84201353036217e-07 7.00464069519324 0.241515547989652 0.0438581465960555 1615.53039099137 784.718869796976 2.05873778899868 0.0404786535687441 -496.074733702586 1470.64627482813 -0.33731750604717 0.736139640339879 FOS og 1 1 1 2.05873778899868 -0.33731750604717 3.20944797271552e-17 1790.16232346202 265.830961710675 6.73421301996564 9.88717463187974e-11 -1338.23917447126 498.195377504977 -2.6861734068536 0.00767555979422654 TMED10 other 4.48295692828904e-13 1 1.32151976129705e-06 6.73421301996564 -2.6861734068536 5.67459240567755e-06 67.8488639929581 14.8081069240318 4.58187291198225 7.11288174975461e-06 -18.7034376436358 41.6694112595947 -0.448852937400913 0.653905961648998 SETMAR other 0.0474243279359797 1 0.0739739701974479 4.58187291198225 -0.448852937400913 1.26573725817294e-10 197.192521265888 52.4227808908542 3.76158070813619 0.000207224762905799 -158.257826067719 75.4969862472391 -2.09621382169419 0.0369975051551496 SMAD1 other 1.43256142880014e-06 1 1 3.76158070813619 -2.09621382169419 0.496657878578635 -85.6895876017648 81.1247894158478 -1.0562688448104 0.291796630659004 -221.590880723377 266.088484843787 -0.832771402541027 0.405715167826369 CST2 other 1 1 1 -1.0562688448104 -0.832771402541027 0.588837656703835 -589.063393862286 646.919624292626 -0.910566586237661 0.363342020492166 -1562.67601122953 2121.8897932832 -0.73645484142303 0.462098088134609 CST1 other 1 1 1 -0.910566586237661 -0.73645484142303 3.22288280843432e-05 48.6952515948109 12.5966122780465 3.86574187725677 0.000138919735576714 -36.4002388318677 35.2547924373486 -1.03249051590801 0.302769757448964 TCAF2 other 0.25170714733872 1 1 3.86574187725677 -1.03249051590801 0.964246688908652 4.72511960839142 35.933075152252 0.13149777992478 0.895482079124057 31.8569415066175 120.143553494374 0.265157310401255 0.791095986422892 SEMA3E other 1 1 1 0.13149777992478 0.265157310401255 0.022895550022662 71.1097099316139 25.7763304655383 2.75872122398043 0.00619793704095899 34.3147304227357 74.2841477072359 0.461938805005541 0.644495815606471 LRRN2 other 1 1 1 2.75872122398043 0.461938805005541 0.185366534020346 55.3824822088907 38.9462580103407 1.42202319396606 0.156165178833506 -105.68128821268 106.74829878915 -0.990004425470254 0.323051813825819 SLC30A1 other 1 1 1 1.42202319396606 -0.990004425470254 0.0131974260419065 -6.24059481756219 21.4762945224521 -0.290580612546454 0.771596821020335 -79.4607605068364 31.6687315044572 -2.50912356548455 0.0126936296063847 DCLK2 other 1 1 1 -0.290580612546454 -2.50912356548455 0.907882418654143 5.07938778208125 15.4510793639148 0.328739996892638 0.742606109224493 -6.59620366385675 39.9032500009034 -0.165304922874889 0.868827228255385 ZNF804A other 1 1 1 0.328739996892638 -0.165304922874889 0.235374937689651 -17.8530600249798 52.7379336050014 -0.338524071851133 0.735228498931826 -203.128260230696 119.192242542848 -1.70420705154259 0.0894802087658668 GPRC5C other 1 1 1 -0.338524071851133 -1.70420705154259 2.91362407429153e-06 50.0770796591045 10.7022560700204 4.67911432238876 4.54720816780838e-06 -51.0741409375523 39.1727711401278 -1.30381740813922 0.19339821133624 TMEM182 other 0.0249435357000098 1 0.047982140586714 4.67911432238876 -1.30381740813922 1.0101672616004e-07 5597.48147913873 1135.60238663124 4.92908569498838 1.43541192595142e-06 -3720.40643422817 2976.75830143113 -1.24981811000225 0.212436361936393 KRT8 other 0.000967740236613184 1 0.0157421625919092 4.92908569498838 -1.24981811000225 0.37079961022785 -21.0027855615717 20.028360006163 -1.04865228880991 0.295265650266375 -65.542877723098 52.5004064928554 -1.2484260999392 0.212944633265436 KRT78 other 1 1 1 -1.04865228880991 -1.2484260999392 6.03454602392476e-10 165.377330111451 26.5339481135585 6.23266953729157 1.73229514206647e-09 -0.553177499425263 69.1202143239626 -0.00800312187737946 0.993620345867574 ADORA2B other 6.6005864409689e-06 1 2.21820392941612e-05 6.23266953729157 -0.00800312187737946 0.802051659238872 7.46848453186751 11.4997620579124 0.649446875009803 0.516595606816463 10.7377884659065 30.7984227225458 0.348647349984127 0.727622801054576 SDR9C7 other 1 1 1 0.649446875009803 0.348647349984127 2.21895392803118e-07 208.164294110956 46.4208255653497 4.48428677378667 1.07978566787324e-05 -9.27709226043824 64.0415636268534 -0.144860489579743 0.884928302389262 MGMT other 0.0020778284582084 1 0.110624041673614 4.48428677378667 -0.144860489579743 0.0245550991200628 22.971099784107 11.4569780545964 2.00498767429263 0.0459551157495398 -33.442123082074 30.499407263737 -1.09648436092185 0.273836689242267 METTL7B other 1 1 1 2.00498767429263 -1.09648436092185 0.0128414420651007 448.527180813895 182.421381390116 2.45874237655673 0.0145657270834897 1175.07793389536 491.296549411428 2.39178951145311 0.0174459152797294 KRT86 other 1 1 1 2.45874237655673 2.39178951145311 2.54241470751593e-19 281.942501976032 42.8156646877454 6.58503153068481 2.33802456305729e-10 -264.566716507972 72.3744543184041 -3.65552623504473 0.000307995439568559 HARS essential 3.68014528912931e-15 1 3.08666002814824e-06 6.58503153068481 -3.65552623504473 1.30343229049833e-19 110.459984215199 16.2151685292944 6.81213914093096 6.83678321915829e-11 -48.9743570810917 26.6360326648367 -1.83865058649461 0.0671249260919564 NFXL1 other 1.89506020715552e-15 1 9.18453457661724e-07 6.81213914093096 -1.83865058649461 0.654143366069553 -74.5255593988747 204.064802463192 -0.365205358784581 0.715241934451561 -505.677273683951 549.766807191538 -0.919803209413794 0.358490602423257 KRT75 other 1 1 1 -0.365205358784581 -0.919803209413794 3.85612736520281e-18 95.4549761942964 9.95664641780623 9.58706096297514 6.86721273184789e-19 40.4268304911194 64.5836673110581 0.625960589949303 0.53187752580496 DENND5B other 5.47570085858799e-14 1 1.04436571225943e-14 9.58706096297514 0.625960589949303 0.670494154578999 -187.083358247095 209.568095725237 -0.892709157849951 0.372807888035968 -165.767742619894 344.335560340199 -0.48141337030691 0.630612667890446 CD14 other 1 1 1 -0.892709157849951 -0.48141337030691 0.000204826984054882 56.4597900813939 18.8600415097023 2.99361960854376 0.0030113825190639 -35.0878168017905 31.0192491110585 -1.13116267502689 0.258986645924063 DNAJC18 other 1 1 1 2.99361960854376 -1.13116267502689 0.935649771725003 131.585092513623 1763.38225373915 0.0746208555941884 0.940571229501118 1718.0083882872 4750.69203407213 0.361633289627191 0.71790684527452 KRT6C other 1 1 1 0.0746208555941884 0.361633289627191 1.74777930822291e-15 95.0329344100546 12.7097095876375 7.4771916505859 1.03832010401149e-12 -17.0041143549865 24.4043747298209 -0.696765008046214 0.486542723553434 RIOX1 other 2.33992693784883e-11 1 1.46217463353265e-08 7.4771916505859 -0.696765008046214 7.0309018011981e-07 17.5929514096223 3.58994544313059 4.90061804234008 1.64655851655006e-06 1.35546382304764 5.90440969805347 0.229568050383513 0.818600606594335 SPATA24 other 0.00633976415414032 1 0.0179787724422101 4.90061804234008 0.229568050383513 6.34594919178615e-22 443.784012714866 46.4062230098743 9.56302805812138 7.53434058212428e-19 -413.524193715542 169.293381205894 -2.44264832310612 0.0152213731851707 RALGAPB other 9.49100161123537e-18 1 1.145596485512e-14 9.56302805812138 -2.44264832310612 0.000859283406950397 47.2142971328084 26.0178818451287 1.81468643042701 0.070673586719403 -177.802973383423 69.6377608973069 -2.55325517495637 0.0112182845867326 PYM1 other 1 1 1 1.81468643042701 -2.55325517495637 0.00662854686198119 -516.348594528833 163.572138012767 -3.15670260719176 0.00177579998045721 -527.023158422448 269.028299541986 -1.95898780656047 0.0511395027040304 MZB1 other 1 1 1 -3.15670260719176 -1.95898780656047 0.529896861911096 -980.837602095834 969.12995795123 -1.01208057190736 0.312395683834401 -2051.81448019744 2541.47860183468 -0.807331007515172 0.420178635952786 KRT4 other 1 1 1 -1.01208057190736 -0.807331007515172 3.29480510887339e-05 6.00901110901789 5.45535576968288 1.10148840198688 0.271661484834639 -30.6640703581771 8.97246379453568 -3.41757526810549 0.000728876950796876 SLC23A1 other 0.257027746543213 1 1 1.10148840198688 -3.41757526810549 0.565080994290087 7.62982657463519 8.39062392170576 0.909327678827023 0.363982217913137 -5.20793492253908 22.6050081547657 -0.23038854429438 0.817963042421155 KRT74 other 1 1 1 0.909327678827023 -0.23038854429438 0.416977783056174 -27.695988293206 55.6033905555481 -0.498098911172289 0.618818302112645 -286.572832436339 220.532481726267 -1.29945861123553 0.19489092997912 NPAS2 other 1 1 1 -0.498098911172289 -1.29945861123553 0.698160870760735 6.79307503348547 8.05552457664123 0.843281522991499 0.399811975232536 4.1764001984215 21.7022238685764 0.192441116805025 0.847540287622655 KRT72 other 1 1 1 0.843281522991499 0.192441116805025 0.0518528591884992 88.114922593662 36.9857906961412 2.38239931971645 0.0178901919376811 -14.4883149419571 146.738720796348 -0.0987354589390542 0.921421306658403 LONRF2 other 1 1 1 2.38239931971645 -0.0987354589390542 3.24395639984504e-15 136.577239140943 35.0912625002282 3.8920582905803 0.000125087968922761 -200.126780546296 54.3617100780838 -3.68139229356175 0.000279705197366155 NUDT9 other 4.31413761615391e-11 1 1 3.8920582905803 -3.68139229356175 0.379584378167435 -31.6332945889961 40.1908098079425 -0.787077810578096 0.431924103248605 -85.588866306063 61.5305857345777 -1.39099709980439 0.165367299599386 HSD17B13 other 1 1 1 -0.787077810578096 -1.39099709980439 5.8684305221837e-10 673.449242065644 118.974370370945 5.66045644928338 3.82792305130189e-08 -520.375953912052 316.719448933077 -1.64301862631116 0.101534530620705 PA2G4 other 6.4241708926345e-06 1 0.00046180063690906 5.66045644928338 -1.64301862631116 0.182333155568145 1.77634128592525 7.28228729406068 0.243926284997573 0.807481019143325 -15.5585052822189 11.9636277663091 -1.30048389887501 0.194591144041791 COX7B2 other 1 1 1 0.243926284997573 -1.30048389887501 1.02324342542766e-05 217.203863223879 58.720977293524 3.69891431026699 0.00026249152082725 -37.0546484257832 91.1194168277455 -0.406660289494963 0.684580867065964 ELOVL6 other 0.0837320095027457 1 1 3.69891431026699 -0.406660289494963 0.163556707885133 31.3597585327523 17.0598882928264 1.83821593638096 0.0671209622233014 50.3477751590978 45.9606958406419 1.09545284809584 0.274287305792521 KRT83 other 1 1 1 1.83821593638096 1.09545284809584 0.000108295495907663 503.259963006554 239.983470462073 2.09706094356232 0.0369183334403583 -769.575248024216 413.558924653997 -1.86085996975662 0.0638508767949428 PFKFB3 other 0.799112464302647 1 1 2.09706094356232 -1.86085996975662 0.000925137201072587 20.459914395268 16.7442688312619 1.22190551295192 0.222805144932387 -80.3141232945931 32.7396804128538 -2.45311262302552 0.0147928850863471 TMC7 other 1 1 1 1.22190551295192 -2.45311262302552 3.0997856120555e-16 1904.13329532718 284.979269521498 6.68165547102554 1.34614798637e-10 -1005.31598143386 557.642710750374 -1.80279587996603 0.0725352505368784 ARL6IP1 other 4.22965746764973e-12 1 1.79279988824757e-06 6.68165547102554 -1.80279587996603 0.202460513821306 -45.9729285500739 63.3996536978496 -0.725129016779365 0.469010292777061 -204.556850703357 114.114565581779 -1.7925568893023 0.0741800352004425 SERPINB9 other 1 1 1 -0.725129016779365 -1.7925568893023 0.00539733095926047 111.435760068879 39.8612873035871 2.79558859251521 0.0055496078307675 -57.025057459087 99.676675058809 -0.572100317606324 0.567726527834268 SMAGP other 1 1 1 2.79558859251521 -0.572100317606324 0.00906171609209282 38.3782767698896 12.9436128580148 2.96503589769571 0.00329696641713088 -44.7654834837978 76.1038735073413 -0.588215571964014 0.556879298181123 IRX1 other 1 1 1 2.96503589769571 -0.588215571964014 0.00416274940400367 261.692045497409 100.40590966261 2.6063410647517 0.00968164154576777 -160.799506894223 208.518610036152 -0.771151826047301 0.441319882805979 CDH2 other 1 1 1 2.6063410647517 -0.771151826047301 4.32274702958232e-08 144.997141821783 24.1221070345267 6.01096502947458 6.00675649233397e-09 109.573514725572 142.52240480483 0.768816067029054 0.442679491760544 IRX2 other 0.000423585981428771 1 7.5288685874914e-05 6.01096502947458 0.768816067029054 0.0360516515573635 -98.3859741840433 71.3764026926954 -1.37841037755342 0.169289504445326 -300.249975977708 115.912616753222 -2.59031315475294 0.0101428483179005 EMB other 1 1 1 -1.37841037755342 -2.59031315475294 0.0999344906163758 74.5686074417667 52.153749998736 1.42978419468541 0.153926558260326 373.051951194919 209.787027284052 1.77824127651995 0.0764812554774685 SIX2 other 1 1 1 1.42978419468541 1.77824127651995 0.081595549059548 50.0858544659461 32.7662827555936 1.52857908355185 0.127561557384967 -65.4519868402232 72.4700989257668 -0.903158513792944 0.367262000236924 DLGAP1 other 1 1 1 1.52857908355185 -0.903158513792944 0.011806955049919 71.268272971819 151.812956413073 0.469447895987893 0.639125614915283 -1067.812398259 404.138435413751 -2.64219461622301 0.00871424723374566 STAT2 other 1 1 1 0.469447895987893 -2.64219461622301 4.61788256413869e-10 141.843456493244 28.1977608506451 5.03030922364882 8.88789220725776e-07 -71.3427386900826 45.7332423315895 -1.5599755244295 0.119924128528212 NUDCD2 other 5.08290333834746e-06 1 0.00988955765901571 5.03030922364882 -1.5599755244295 1.05977959912815e-20 196.941141391854 24.7338282362678 7.96242051616879 4.66469783097544e-14 -191.11698729799 61.041901842392 -3.13091469186933 0.00193330920175176 IRF2BP1 other 1.56296295279419e-16 1 6.72556133270039e-10 7.96242051616879 -3.13091469186933 5.50833880796354e-17 1157.01506956984 155.970910005396 7.41814656034137 1.50594402676835e-12 -301.06028606993 249.900868629461 -1.20471884600099 0.229355192413123 HSPA4 other 7.64887926873817e-13 1 2.11299006395867e-08 7.41814656034137 -1.20471884600099 7.58974730762424e-11 127.537495272032 17.9227278329395 7.11596451504642 9.87409447829762e-12 108.259286922939 47.9119358808321 2.25954733267728 0.0246408163477645 FOXA3 other 8.68191194519137e-07 1 1.3589716230481e-07 7.11596451504642 2.25954733267728 8.62466576108187e-18 146.660564544702 16.1477460560442 9.08241707763331 2.90921427600341e-17 -31.1306784629096 60.321891544003 -0.516075966221993 0.606245073112542 COMMD5 other 1.21771655880715e-13 1 4.36556694257071e-13 9.08241707763331 -0.516075966221993 0.850867752048817 -12.1886594923935 22.0822445980309 -0.551966510391808 0.581422855675463 -13.9044394352383 36.3236951382648 -0.382792537551907 0.702171462394818 SGCD other 1 1 1 -0.551966510391808 -0.382792537551907 0.0211027989116854 124.122401771667 44.526648161407 2.7875981439638 0.00568297039836769 81.3936495786305 120.413364402017 0.675951959176941 0.499643355986507 GTSF1 other 1 1 1 2.7875981439638 0.675951959176941 4.24458983426553e-05 16.1552290371501 3.60209865825498 4.48494907270985 1.08113974875604e-05 4.13281618776928 14.2849228687899 0.289313160857087 0.77256459263046 DPY19L2P2 other 0.327427659815243 1 0.110751955862569 4.48494907270985 0.289313160857087 4.70001186387562e-14 61.0585921814099 7.66543317340023 7.96544576153751 5.34780321526049e-14 -5.54106960713788 28.6351684574934 -0.193505745054832 0.846715754102431 ZNF16 other 6.0536152806718e-10 1 7.70351053158274e-10 7.96544576153751 -0.193505745054832 1.73261105685124e-25 213.497805541885 19.7180638122385 10.82752381648 6.48710507978033e-23 -159.143897699083 78.1963647870095 -2.03518281358165 0.0428127360209049 ARMC10 other 2.66146384442919e-21 1 1.00640948207712e-18 10.82752381648 -2.03518281358165 4.7904426356874e-12 157.489371115722 28.5088851851214 5.5242206102789 7.73787297808783e-08 -182.511692290178 59.0766791831234 -3.08940337902942 0.00221337464836853 RNF34 other 5.74326167592562e-08 1 0.000920342612013767 5.5242206102789 -3.08940337902942 0.00633475649043678 23.2468819519661 8.66279905277183 2.68353009348956 0.0077382827652868 -65.0386155227417 41.2748520691988 -1.57574436399438 0.116264407481893 ACYP2 other 1 1 1 2.68353009348956 -1.57574436399438 3.56496717816402e-12 273.801747718496 52.8650565479985 5.17925763438651 4.40300890445511e-07 -322.377588505537 112.738608283936 -2.85951364321988 0.00457916089718947 TRABD other 4.30184589389052e-08 1 0.00500137781457056 5.17925763438651 -2.85951364321988 0.772146340232706 -0.152382405094718 5.84288112613043 -0.0260800111803124 0.97921278543073 -6.64065418887458 10.5444173857641 -0.629779147194997 0.529371657857762 TMEM133 other 1 1 1 -0.0260800111803124 -0.629779147194997 8.47760029628354e-05 77.1305286545215 43.0732155735842 1.79068424837601 0.0744518489209705 -370.653221234757 116.570894372121 -3.17963779235961 0.00164447600041283 ATF7 other 0.633700622147195 1 1 1.79068424837601 -3.17963779235961 0.481295434403024 -0.801721507103569 12.0381764828594 -0.066598251674172 0.946951008094762 -58.1345439066424 49.0528754450299 -1.1851403894108 0.237007873634804 RASA4B other 1 1 1 -0.066598251674172 -1.1851403894108 7.03935541115915e-13 196.480898342623 36.1875319093835 5.42951917347187 1.2630936143069e-07 -108.444092057492 58.3770359694075 -1.85764984906603 0.0643114055370767 SOCS6 other 8.72809677429623e-09 1 0.00148501916234063 5.42951917347187 -1.85764984906603 0.00287945163890359 6.48818251436705 1.88273681966389 3.44614416980773 0.000659615846621456 4.53257964329256 3.62359928832086 1.25085013067019 0.212076013389883 CAVIN4 other 1 1 1 3.44614416980773 1.25085013067019 9.47982334602913e-05 16.8838068112548 7.57110582177055 2.23003180892093 0.0265645315416388 -59.4731907423041 21.4457117897453 -2.77319733312571 0.00593618141053418 ZNF296 other 0.704592544290368 1 1 2.23003180892093 -2.77319733312571 0.347220716620246 21.4170997462451 89.7244244532568 0.238698658439461 0.811520328057581 -252.920352839217 197.747340171379 -1.27900760950829 0.201992527614704 HOXB9 other 1 1 1 0.238698658439461 -1.27900760950829 2.72504968378252e-13 81.2413556185898 11.8516078503219 6.85488050605584 4.83851398219191e-11 -49.7252173216927 28.9237327505972 -1.71918395701073 0.0867269821856228 POLH other 3.425659957483e-09 1 6.53102617316264e-07 6.85488050605584 -1.71918395701073 0.344546938846342 11.8356584866744 8.422227926622 1.40528831442127 0.161072494384402 15.5875637454729 13.2884122286898 1.17301928004756 0.241810537203101 SYT9 other 1 1 1 1.40528831442127 1.17301928004756 0.0444511829780237 131.504587418724 63.2157851909837 2.08024921341133 0.0384528061153365 -192.167658884161 206.831379106383 -0.929103019640555 0.353671770259736 KCNS3 other 1 1 1 2.08024921341133 -0.929103019640555 3.36808333714045e-18 884.970991730743 167.976092628437 5.26843420324283 2.79517055824446e-07 -1216.28998782538 289.417655345322 -4.20254246885579 3.57919873953531e-05 KIF5B other 4.78941450541372e-14 0.542570736926158 0.00321724131253938 5.26843420324283 -4.20254246885579 0.616555788746371 -8.53642701042557 13.8093839279493 -0.618161320951357 0.536984365106312 -35.7728910594438 37.8462511730833 -0.945216235442783 0.345384306038293 GPR37 other 1 1 1 -0.618161320951357 -0.945216235442783 2.32330595739753e-29 543.23546433165 45.1706012175764 12.02630582035 5.54132228234536e-27 31.4427276558126 108.380637964488 0.290113882390276 0.771950978306675 CDCA4 other 3.63039788902939e-25 1 8.69710532214105e-23 12.02630582035 0.290113882390276 0.181753283128174 44.8500358422932 52.1573700710146 0.859898338072411 0.390634229239867 -198.506881720431 159.712936923477 -1.2428979489341 0.215020848840661 SDR16C5 other 1 1 1 0.859898338072411 -1.2428979489341 1.24743250572961e-10 198.103066507367 30.7253923963197 6.44753576950561 5.47121991541828e-10 -44.2498805256877 94.0853162469857 -0.470316541313696 0.63852164526882 CHCHD7 other 1.41246782623764e-06 1 7.13447076970544e-06 6.44753576950561 -0.470316541313696 0.186832170852377 -225.765075644577 216.553817553236 -1.04253565324045 0.298095968366602 -580.807552983987 318.710222179043 -1.82236876185824 0.0695051270301616 HTRA3 other 1 1 1 -1.04253565324045 -1.82236876185824 3.68901120724044e-13 181.113608313807 22.7144209421626 7.97350761328999 4.43231716647638e-14 133.70347779944 113.007998920265 1.18313286738027 0.237801067286141 FOXN2 other 4.61642862474069e-09 1 6.39406074435882e-10 7.97350761328999 1.18313286738027 0.949647166359127 -21.4144228977234 66.7176276024634 -0.320970988736607 0.748478851368197 -17.8823431323506 126.415739407916 -0.141456619374334 0.887613938641627 CELP other 1 1 1 -0.320970988736607 -0.141456619374334 2.17991149207902e-13 208.665395023154 29.3286309856063 7.1147335559427 1.03180070319185e-11 -101.16890831613 62.9487382942426 -1.60716340084903 0.109200421366026 USP32 other 2.74974035610848e-09 1 1.41913868717006e-07 7.1147335559427 -1.60716340084903 0.933891655845482 -133.923677525038 364.359454490961 -0.367559221736511 0.713487758877531 -125.079502318005 690.383808671866 -0.181173864083846 0.856366035944655 CEL other 1 1 1 -0.367559221736511 -0.181173864083846 7.05986552741823e-11 84.0305330659191 14.2844258698871 5.88266786718137 1.19997372367085e-08 -66.9927435846695 30.7521798151268 -2.17847137950579 0.0302425271601113 PPM1D other 8.08707596165758e-07 1 0.000148520747778742 5.88266786718137 -2.17847137950579 0.15844520183352 45.8961806335651 23.8919791741856 1.92098696800951 0.0557785166202868 46.6509248857929 51.1414014335236 0.912194886689454 0.362473901987056 GPR27 other 1 1 1 1.92098696800951 0.912194886689454 1.62455410393761e-16 267.421300427823 36.1168467836807 7.40433687440999 1.65587240846599e-12 -259.936344648062 96.9435681595999 -2.68131604378461 0.00778152169689167 KBTBD2 other 2.23035032929595e-12 1 2.32136752942847e-08 7.40433687440999 -2.68131604378461 3.75890516187286e-12 212.144871018223 35.6363915487027 5.95304018725616 8.56084856313598e-09 -354.440716192581 128.477310984233 -2.75878062419971 0.00621706850899657 RIOX2 other 4.5321119536701e-08 1 0.000106633929702422 5.95304018725616 -2.75878062419971 3.45545513692678e-06 137.705227230532 29.5590410741628 4.6586500179432 4.99417635532004e-06 -35.2290413564905 61.6787740086253 -0.571169610984226 0.568358032910311 TRIAP1 essential 0.0293990123049731 1 0.0525237527289009 4.6586500179432 -0.571169610984226 1.15318543240353e-26 370.986842826598 35.8650109646366 10.3439768411725 2.2428391206494e-21 -257.488460062495 98.0643483599466 -2.62570918349836 0.00913470198671919 LSM3 essential 1.78144085597697e-22 1 3.45486938144833e-17 10.3439768411725 -2.62570918349836 3.71646375735461e-14 191.375161510431 59.5767369782273 3.21224644411744 0.00147601151468369 -341.434718330649 89.8366924118307 -3.80061541853565 0.000178293929983387 KIAA0232 other 4.80204282087789e-10 1 1 3.21224644411744 -3.80061541853565 2.80562038211913e-05 522.410993357715 113.02620798734 4.62203415172727 5.90310451063317e-06 51.237633405478 495.960801655845 0.103309844718399 0.917794038993558 MTSS1 other 0.220493705830742 1 0.0617051514496485 4.62203415172727 0.103309844718399 2.51153557963784e-19 1024.34111650086 108.437147333354 9.44640413078977 1.64842138970049e-18 10.7393700841368 296.374271691393 0.0362358379586991 0.971120791558009 TMEM43 other 3.63645236575763e-15 1 2.49983103748079e-14 9.44640413078977 0.0362358379586991 1.0788982162783e-10 160.684169212364 22.8131757720835 7.0434809610766 1.55714418494763e-11 53.6514605379913 98.7612372335485 0.543244111159903 0.587409943470998 RNF139 other 1.22498103476238e-06 1 2.13126324593782e-07 7.0434809610766 0.543244111159903 0.0066387240084834 1180.44011618456 430.320478762466 2.74316509309369 0.00648781499826844 -586.419146069645 1100.07382275492 -0.533072539260205 0.59441704245915 RPS9 other 1 1 1 2.74316509309369 -0.533072539260205 0.91891416386583 -3.31243431737844 11.4444913031774 -0.289434823237516 0.772471600826836 4.44938855450461 23.902593508745 0.18614668541624 0.852470027797197 PLA2G1B other 1 1 1 -0.289434823237516 0.18614668541624 0.281407801953816 -3.37132774773587 9.40141117908342 -0.358598053368468 0.720174999439194 -21.2185468851067 14.8113815878992 -1.43258390577433 0.153129277123615 CYTL1 other 1 1 1 -0.358598053368468 -1.43258390577433 4.23752164719433e-19 290.497388120356 34.620158192086 8.39098962253623 2.62778211717924e-15 -172.895174910527 88.5031776230445 -1.95354765279646 0.0517759786296601 TSEN34 essential 6.11643874556029e-15 1 3.85994915192459e-11 8.39098962253623 -1.95354765279646 0.0158091334488794 -33.8591627896047 31.296569745054 -1.08188095581803 0.280263640835073 359.564218243339 145.121578121786 2.47767577294117 0.01383169467344 TRH other 1 1 1 -1.08188095581803 2.47767577294117 0.00299397183690022 204.303423013146 79.0450814357859 2.58464434854327 0.0102811933824624 -246.523286963016 188.827497643518 -1.30554760318024 0.192834490148666 GSTA4 other 1 1 1 2.58464434854327 -1.30554760318024 2.8786370333085e-28 229.267508068564 18.2416736534884 12.5683373370031 7.47715193562601e-29 102.875416688768 40.2373215462859 2.55671632045458 0.0111119600560209 MSANTD4 other 4.47829563271804e-24 1 1.17720280074496e-24 12.5683373370031 2.55671632045458 1.32239484773445e-14 187.544981682862 27.8658969276018 6.73026897968229 9.94131210901592e-11 -169.110585184104 71.2365440887199 -2.37393022566464 0.0182918924412 NDUFA3 other 1.72784110804983e-10 1 1.32865636336998e-06 6.73026897968229 -2.37393022566464 0.32405560431233 -2.81928639629068 20.4474629558053 -0.137879520915833 0.89043764942323 -74.9449065804169 51.8127503420884 -1.44645682936344 0.14920046195799 OSCAR other 1 1 1 -0.137879520915833 -1.44645682936344 0.581538248297279 1.21589888967634 23.4453292436779 0.051861028567309 0.95867820536897 -48.1807642334041 50.4726792809263 -0.954590977135063 0.340648025682877 PAQR8 other 1 1 1 0.051861028567309 -0.954590977135063 1.56251546206761e-11 23.4466995130236 5.82084559044763 4.02805728973487 7.31563134758563e-05 -23.7168029027934 8.78073653913981 -2.70100381637425 0.0073502785402933 NUDT6 other 1.84095571740806e-07 1 0.696374947976676 4.02805728973487 -2.70100381637425 0.0292211777442653 162.629302872933 61.0266981997784 2.66488778961212 0.00816337923683105 118.984591798249 133.052426941921 0.89426848147751 0.371971778211083 TANC2 other 1 1 1 2.66488778961212 0.89426848147751 0.801000257619039 6.65337660466131 10.0391009029834 0.662746262733956 0.508064780007657 6.56266845048922 21.5816036306391 0.304086228382598 0.7612990498809 PKHD1 other 1 1 1 0.662746262733956 0.304086228382598 2.17779819486312e-12 48.5118064635599 7.85989893683235 6.17206491501159 2.55034649107673e-09 -18.2294362146272 15.2546286582608 -1.19501015875306 0.233163659984672 DNAJC24 other 2.6508159627874e-08 1 3.24506087524603e-05 6.17206491501159 -1.19501015875306 2.79142268867928e-05 83.8255385271337 25.8250795605226 3.24589662272612 0.00131908867269253 -128.200393497877 65.9418650625663 -1.94414266833732 0.0529207144723485 ZNF160 other 0.219461651783965 1 1 3.24589662272612 -1.94414266833732 0.81951338320079 5.82952877169749 9.24329950868667 0.630676174262125 0.528783768936474 6.01086099196866 23.5282768568181 0.255473914581501 0.79855087873861 ZNF415 other 1 1 1 0.630676174262125 0.255473914581501 0.0211930084878306 48.7583971638541 63.5359492633914 0.767414317864738 0.443498415974659 -158.819484885443 96.4378964102032 -1.64685762337554 0.100737889674276 CAVIN3 other 1 1 1 0.767414317864738 -1.64685762337554 0.412335522531303 0.621030261044364 3.42193909315669 0.181484896176651 0.856122652107204 -11.7880209439415 9.86293334257913 -1.19518408312176 0.233059977233416 CEACAM3 other 1 1 1 0.181484896176651 -1.19518408312176 0.563412648736509 40.8143290950421 38.0980930925225 1.07129585189272 0.284989564112125 22.7156733911067 168.285491839338 0.134982957489843 0.892725549752778 HAS2 other 1 1 1 1.07129585189272 0.134982957489843 0.00754368842179332 54.6178909425919 17.3746666233403 3.14353605318796 0.00185609460226289 51.6145835337154 38.4607159761164 1.34200787020625 0.180725065964574 PDGFD other 1 1 1 3.14353605318796 1.34200787020625 0.577098529431938 161.986659396903 157.134154827326 1.03088128468893 0.303515639257091 175.834470490243 226.25093427241 0.777165721130394 0.43773886513756 S1PR1 other 1 1 1 1.03088128468893 0.777165721130394 0.00727473394591231 62.3978244778425 22.4457239906937 2.7799426074968 0.00582054653233182 -10.8718887780389 43.6408303199705 -0.249121950667006 0.803456558595088 PYGO1 other 1 1 1 2.7799426074968 -0.249121950667006 1.43648343715476e-13 239.969194178771 39.8530069584261 6.02135729504932 5.56396929424066e-09 -179.060415640583 91.8526842216572 -1.94943040759133 0.0522678966575046 LRRC8E other 1.8220355916871e-09 1 6.98278146427203e-05 6.02135729504932 -1.94943040759133 0.0127278677785676 92.4414875967052 32.3181032958483 2.8603624027831 0.00456601140471717 27.5348072796974 100.861558743922 0.272996051445185 0.785067280291179 PKIA other 1 1 1 2.8603624027831 0.272996051445185 1.61948922014258e-11 18.5575739918049 3.59423138562356 5.16315506732057 4.70628763482812e-07 -7.02187146007073 6.35866872396273 -1.10429899164407 0.270442991777396 XKR6 other 1.90678660779588e-07 1 0.00533128263273329 5.16315506732057 -1.10429899164407 6.19133485524356e-11 157.051809939023 22.6647687748003 6.92933651781353 3.07974266418726e-11 -9.60592634732179 86.0340823654798 -0.111652569344728 0.91118153963418 TSNARE1 other 7.1101289477617e-07 1 4.17736294970359e-07 6.92933651781353 -0.111652569344728 0.830346512887303 -8.26488589430409 14.262035538626 -0.579502545195617 0.562728024429639 -1.4095503429717 32.9967852828072 -0.0427178081407263 0.965957710079613 FPR2 other 1 1 1 -0.579502545195617 -0.0427178081407263 0.83741550994423 -12.1917497229327 35.8581066704009 -0.339999817474924 0.734118112353555 -48.2493758796167 82.961667235139 -0.581586381851067 0.56132521827935 FPR1 other 1 1 1 -0.339999817474924 -0.581586381851067 6.59894649684149e-11 196.878718535469 28.2253638905852 6.97524110933214 2.3208688752537e-11 212.360945842869 104.250452348554 2.03702661291919 0.0426154667995072 FEZ2 other 7.56767184257782e-07 1 3.16009506054543e-07 6.97524110933214 2.03702661291919 0.00449472658234197 16.9368637450646 84.3164152135732 0.200872673513972 0.840948810847352 -376.615077592918 149.166843982191 -2.52479081502778 0.0121478631168428 SOX7 other 1 1 1 0.200872673513972 -2.52479081502778 2.20579456471041e-44 491.654166451934 29.1400872068499 16.8720897422833 6.336305935703e-44 5.77407102667469 122.032868512521 0.0473157035236147 0.962297116997765 C11orf24 other 3.50721335788955e-40 1 1.00797954825163e-39 16.8720897422833 0.0473157035236147 1.73300259901306e-10 79.6169895801908 11.5030344194678 6.92139018948309 3.27306794792634e-11 13.8705460598977 43.608916679666 0.318066742216627 0.75068109148817 FAM86JP other 1.94841482207038e-06 1 4.43664360341416e-07 6.92139018948309 0.318066742216627 0.139994121943989 12.8171402574856 6.44855234085034 1.98759963167104 0.0478549456807787 -2.46429679520032 24.7105742269742 -0.0997264075114158 0.920634727070674 ALK og 1 1 1 1.98759963167104 -0.0997264075114158 3.22635838819195e-07 34.6551083976839 10.9615917349296 3.16150329584471 0.001747821189455 -59.7150077635796 20.428481024744 -2.92312520403498 0.00375788457335728 KYAT1 other 0.00299051159001512 1 1 3.16150329584471 -2.92312520403498 0.470868246100614 -2.3724919636192 2.15638114313811 -1.10021921271608 0.272216574338624 -4.39651477526068 4.73391985646921 -0.928726068155242 0.35386059256347 SIGLEC17P other 1 1 1 -1.10021921271608 -0.928726068155242 3.39430442881969e-10 86.4933197587909 12.598157994124 6.8655528688506 4.45466260662037e-11 23.5894048955369 48.3191161231235 0.488200256714713 0.625799885443047 TRMT61B other 3.76224702890375e-06 1 6.01557638398015e-07 6.8655528688506 0.488200256714713 0.000135030124163439 95.3092185932446 59.4921017711948 1.60204826784909 0.110301343317545 -366.305248127565 132.551129640643 -2.76350151915453 0.00610745188483662 INSR other 0.98423457502731 1 1 1.60204826784909 -2.76350151915453 2.24046201677493e-27 306.514264286691 25.0178184377218 12.2518382268108 1.38019060066869e-27 731.633703026005 270.566026729972 2.70408562327074 0.00729773564732078 MFN1 other 3.47294017220282e-23 1 2.16855547177065e-23 12.2518382268108 2.70408562327074 0.285342685906175 -37.2469831550804 50.465718185519 -0.738065056721383 0.461111208998631 -202.26735752651 127.634444252965 -1.58473959525868 0.114187423355135 GIMAP8 other 1 1 1 -0.738065056721383 -1.58473959525868 1.30453053255651e-06 19.960444971134 3.95677265347581 5.04462771031331 8.31758594660052e-07 8.80594518349944 7.45862937791111 1.18063852449599 0.238777742170406 NRTN other 0.0115150910108764 1 0.00927410833045958 5.04462771031331 1.18063852449599 1.19840283919877e-29 79.2594159602671 6.05891787637972 13.0814474758363 1.96232671244682e-30 114.632981067254 65.5267900427111 1.74940632667243 0.0813916825459666 KCNMB3 other 1.87514092249432e-25 1 3.0975327155973e-26 13.0814474758363 1.74940632667243 0.020946336354878 -152.162972147339 80.0377398089899 -1.90114029344752 0.0583404669662548 -414.111040091117 150.711008908829 -2.74771593057034 0.00640237536220886 FUT3 other 1 1 1 -1.90114029344752 -2.74771593057034 6.9416298516062e-05 16.3008875526158 3.66046472883426 4.45322896412857 1.23447168370524e-05 9.35121667668867 14.7372178362645 0.634530667903799 0.52626593401419 KCNG3 other 0.524093053796268 1 0.125842043436912 4.45322896412857 0.634530667903799 0.000140685886014733 201.260447779464 59.1991072094341 3.39972099693068 0.00077724787872596 -160.749488321991 151.25665036052 -1.06275980552818 0.288847579225839 ATP6V0E2 other 1 1 1 3.39972099693068 -1.06275980552818 0.698089765549578 -12.728275488781 30.4123462061829 -0.418523299797016 0.675898499934576 -95.8367832305473 122.114127931724 -0.784813230489854 0.433253693819376 PRKCE other 1 1 1 -0.418523299797016 -0.784813230489854 2.68367538693963e-25 236.873641952779 23.4345010276284 10.1079020916005 1.33674560457145e-20 -180.401697734484 65.1168314589037 -2.77043114188286 0.00598396589941193 JAGN1 other 4.1167580435654e-21 1 2.0521718521381e-16 10.1079020916005 -2.77043114188286 2.59949126237456e-24 515.239570758819 52.2936037959755 9.85282201565293 8.77417673115407e-20 -394.305802756805 145.306861056978 -2.71360760179237 0.00708047535154845 TADA3 essential 3.96500402249992e-20 1 1.34218581456464e-15 9.85282201565293 -2.71360760179237 2.07932808192236e-05 80.2130000959419 17.7486517078972 4.51938555198822 9.32610537636208e-06 142.66740599897 73.1214930315738 1.95110083347678 0.0520908612035151 SOCS5 other 0.165618481725116 1 0.096021580955024 4.51938555198822 1.95110083347678 2.19495738177525e-06 146.493509086159 51.1005489598797 2.8667697719094 0.00447114146801138 -264.516815925969 95.1306126645467 -2.78056462075692 0.00580542942540726 C9orf16 other 0.0189973561392648 1 1 2.8667697719094 -2.78056462075692 0.000441644686658431 10.3544477969673 14.7265403678347 0.70311475325075 0.482583405221038 -72.3090651185569 23.4570849382874 -3.08261087465867 0.00226195544613187 MORN4 other 1 1 1 0.70311475325075 -3.08261087465867 4.33583101693963e-05 111.206287315886 29.3638624350639 3.78718186552642 0.000189921648501042 -164.872386625947 79.0601705521147 -2.08540388256899 0.0380232812247684 ZNF672 other 0.334162496475538 1 1 3.78718186552642 -2.08540388256899 0.081739950498423 76.7813923731608 41.1415065413686 1.86627566241298 0.063150682011477 -116.897051035724 111.292933727606 -1.05035465523656 0.29454948224688 ZNF692 other 1 1 1 1.86627566241298 -1.05035465523656 0.00244880865567742 31.3437777529012 8.94063858970482 3.50576498965003 0.000532344874852075 25.2389007052502 16.6442131046122 1.51637692611953 0.130585359837181 NAIF1 other 1 1 1 3.50576498965003 1.51637692611953 0.189899815194636 11.4486973891515 6.30937443789868 1.81455348732868 0.0706900549698096 -4.83542932703131 23.5994007977802 -0.204896275480271 0.837805847853773 RBKS other 1 1 1 1.81455348732868 -0.204896275480271 0.339179543248728 -14.6349490218571 23.6571094264069 -0.618627946384738 0.536683031302259 -71.2328751489978 48.6152669094292 -1.46523673893852 0.14401983226502 MUC7 other 1 1 1 -0.618627946384738 -1.46523673893852 2.07476893834136e-12 66.8294789795542 14.9203408965913 4.47908525969551 1.10608135770656e-05 -111.452874668992 31.6840700958219 -3.51763123651494 0.000510385061007337 TMEM126A other 2.52727604379361e-08 1 0.113174244520536 4.47908525969551 -3.51763123651494 3.56730004892017e-08 109.833724155036 29.374960640639 3.73902540666166 0.000225388967148712 -155.961500304391 62.3791586566663 -2.50021808025337 0.0130029099355684 TMEM126B other 0.000351165016815702 1 1 3.73902540666166 -2.50021808025337 1.15338842887202e-09 50.6443127256716 161.738144812935 0.313125347049371 0.754425395117602 -1270.03932495567 240.961433290543 -5.27071617898416 2.77059073035057e-07 TRIM8 other 1.24127662715207e-05 0.00436395745937519 1 0.313125347049371 -5.27071617898416 0.00173528188572753 172.13694250659 69.8649663679197 2.46385207716398 0.0143931108076554 -94.9234795864406 123.660409041762 -0.767614148473206 0.443412994477742 NETO2 other 1 1 1 2.46385207716398 -0.767614148473206 0.700612526022016 -113.084167426858 229.417404433155 -0.492918868584823 0.622467600798839 -396.157613515386 470.974721681071 -0.841144110880012 0.401006064174731 CSN3 other 1 1 1 -0.492918868584823 -0.841144110880012 0.69037446295436 4.79677186681192 7.85629081553626 0.610564448215948 0.541995922592186 11.8114846763035 15.3217723528651 0.770895455452635 0.441435563118221 CLDN20 other 1 1 1 0.610564448215948 0.770895455452635 0.00217911728636377 -15.6652966170054 56.5938469653502 -0.276802116431429 0.78214306035886 -447.664630845324 130.104284851048 -3.44081389293088 0.00067147095644215 CDC42BPG other 1 1 1 -0.276802116431429 -3.44081389293088 1.69097161413229e-19 307.658641380448 33.3562348655135 9.22342232631692 8.87239317766725e-18 -243.87972452788 139.858608862134 -1.74375911867024 0.0823477467082733 SCAND1 other 2.45427620075161e-15 1 1.33751327153334e-13 9.22342232631692 -1.74375911867024 0.0374633428509127 534.237663812665 353.549859495313 1.51106739110371 0.131940740298319 -907.30839073104 789.732930910972 -1.14888002667489 0.251622209209617 JUNB other 1 1 1 1.51106739110371 -1.14888002667489 0.430273587966393 39.566414640433 42.7113404158145 0.926367897968919 0.355073022331304 -77.1258913996048 129.998957596093 -0.593280844906733 0.553484402512131 TMEM37 other 1 1 1 0.926367897968919 -0.593280844906733 0.0278085073311452 23.359831350388 11.8474932487506 1.9717108809369 0.0497407545342731 -19.9584321150694 29.4402456592045 -0.677930216551348 0.498440396886795 UGT2B7 other 1 1 1 1.9717108809369 -0.677930216551348 0.0627607279223352 -180.507931199342 81.1398620654786 -2.22465168912507 0.0269222678630846 -91.8209728429093 147.909950957867 -0.620789691621661 0.535255933704087 LRG1 other 1 1 1 -2.22465168912507 -0.620789691621661 2.00166939655413e-11 111.495114489272 22.4453550424537 4.96740257743248 1.23081168973442e-06 -65.3918092614128 39.7280916306558 -1.64598415321198 0.100975261388152 SHCBP1 other 2.34695736745971e-07 1 0.0135610831974939 4.96740257743248 -1.64598415321198 0.08207359216548 201.769460061936 97.4937153113312 2.06956376026512 0.0394373764868841 -91.6180664750018 262.287117661048 -0.349304484688414 0.727131001894297 SOSTDC1 other 1 1 1 2.06956376026512 -0.349304484688414 0.341867989303986 98.8318006661133 92.2164059581099 1.07173771997803 0.28479488315083 -131.436051402136 204.591537967518 -0.642431513580015 0.521138161707973 NPTX1 other 1 1 1 1.07173771997803 -0.642431513580015 3.90863161076728e-10 248.679940096337 46.6138880519951 5.33488946081795 2.02502845508131e-07 -80.4858064083516 81.5568076175581 -0.98686803419 0.324590867897994 FAM98B essential 4.32216483518646e-06 1 0.00235166554488593 5.33488946081795 -0.98686803419 0.753633621266146 0.6072624807273 8.04279565426844 0.075503905212986 0.939869911384868 -10.9485922392776 17.547252269315 -0.623949098767072 0.533189770536337 ZNF439 other 1 1 1 0.075503905212986 -0.623949098767072 6.29598936221931e-08 89.7967249720875 30.026131859528 2.99061915108433 0.00304210591582043 -203.59155723324 65.5090758312668 -3.1078374202322 0.00208663072248068 ZNF440 other 0.000610459128560785 1 1 2.99061915108433 -3.1078374202322 0.00168101753756204 754.971940408732 225.043129091916 3.35478778425789 0.000908162081689177 -159.941605795944 506.461338910175 -0.315802201487113 0.752396620955858 GAA other 1 1 1 3.35478778425789 -0.315802201487113 3.01522220760713e-13 437.355474488345 57.693238800108 7.58070587792215 5.38651661179065e-13 -40.9047885224519 129.489498892133 -0.315892708462223 0.752325315606178 CANT1 other 3.78289778166391e-09 1 7.63484864555207e-09 7.58070587792215 -0.315892708462223 0.655979808504143 11.6669249979189 61.1120914227149 0.190910255668036 0.848737802458515 -203.169871805544 228.059317732226 -0.890864156859814 0.373786495236349 KCNK3 other 1 1 1 0.190910255668036 -0.890864156859814 2.90587732087987e-24 244.363665747523 27.3409823500068 8.9376329869677 6.10529585717593e-17 -87.3215412803871 43.5499261375145 -2.00509045651784 0.0459404222475413 ZDHHC16 other 4.43000997568137e-20 1 9.1341331319209e-13 8.9376329869677 -2.00509045651784 0.804115242337979 -55.1307931360624 85.6099505600691 -0.64397646272882 0.520131347398213 -11.3359692873463 184.63435242695 -0.0613968589178516 0.951088077896177 CHST11 other 1 1 1 -0.64397646272882 -0.0613968589178516 1.54227270686051e-19 160.912038531616 19.7350393502225 8.15362136735756 1.29137529434708e-14 -38.3769753594818 31.4348436724299 -1.22084193449133 0.223199238954055 EXOSC1 essential 2.23984265217352e-15 1 1.87882191574556e-10 8.15362136735756 -1.22084193449133 4.58397152624604e-18 1912.16452470903 202.476384172861 9.44388913561666 1.67852770525737e-18 954.477330313964 322.513341416823 2.95949719822715 0.00335181746789617 PGAM1 essential 6.50190521282739e-14 1 2.54531941225228e-14 9.44388913561666 2.95949719822715 1.09628726719693e-06 150.508850191144 43.6062316227208 3.45154452907877 0.000648526718803852 -343.257043903456 131.6300819641 -2.60774010607297 0.0096310787392815 CHD7 other 0.00973283835817431 1 1 3.45154452907877 -2.60774010607297 5.32724930327073e-15 124.60468754341 20.800998761571 5.9903223384452 6.61371788650524e-09 -41.1208184714946 35.3125951416841 -1.1644802175118 0.245249778741545 ESCO2 other 7.04581992850587e-11 1 8.27309970422941e-05 5.9903223384452 -1.1644802175118 0.240173919275907 4562.0862832936 3015.1813520599 1.51303876968358 0.131426590840666 -104.128434920676 5830.11964283369 -0.0178604284817154 0.985763243511164 KRT19 other 1 1 1 1.51303876968358 -0.0178604284817154 0.00113326738943199 10.6778404990692 4.86842745856788 2.19328327061285 0.0291335654673863 -12.3650559889447 8.55488135142813 -1.4453801848322 0.149502249257881 LURAP1 other 1 1 1 2.19328327061285 -1.4453801848322 0.0732379933448848 79.4814441952844 35.3365717690733 2.24926868159992 0.0253167277697338 150.117225270331 203.411764400099 0.737996770801611 0.461169428834146 TPPP other 1 1 1 2.24926868159992 0.737996770801611 0.0580081283081253 64.2300649107924 49.2446555933015 1.30430529236008 0.193228073029772 -53.0356925495159 72.622483187383 -0.73029301976182 0.465837313991868 KCND3 other 1 1 1 1.30430529236008 -0.73029301976182 0.2746931398747 -866.906707522218 5187.35784051566 -0.167119125800668 0.867400036943311 -15215.2720892686 10060.1328800506 -1.51243251661624 0.131580598293153 KRT13 other 1 1 1 -0.167119125800668 -1.51243251661624 0.617402776506411 6.09211635078455 10.8633249318785 0.560796661149959 0.575396131783122 20.4090853865016 21.0051989173258 0.971620667189567 0.332099366170247 KRT9 other 1 1 1 0.560796661149959 0.971620667189567 0.231493532270816 -2.75282287317863 8.1968415521943 -0.335839463975207 0.737251791303703 -25.5410252253736 14.9822845690994 -1.70474837182383 0.0893874070890747 PDE7B other 1 1 1 -0.335839463975207 -1.70474837182383 4.34311226892879e-12 132.389335147922 17.4278604075539 7.59641929944193 5.19593585090453e-13 56.1496566271335 102.830345636421 0.546041698874209 0.585494934520799 MRPL36 other 5.21824939111794e-08 1 7.36679784941245e-09 7.59641929944193 0.546041698874209 8.41780066186176e-16 96.1206439363778 15.0610262653947 6.38207797016009 7.5732279787789e-10 -103.52356969374 33.6737550090544 -3.07431023555002 0.0023260931445268 ZNF581 other 1.13631891134472e-11 1 9.82626330246563e-06 6.38207797016009 -3.07431023555002 3.88623968366624e-05 25.5251290351741 9.79379895567384 2.60625413597924 0.0096584137752528 -23.5548986013838 16.5454438529598 -1.42364863769853 0.155694283683862 NAT1 other 0.300911538706277 1 1 2.60625413597924 -1.42364863769853 0.273876395799104 -73.1955389998285 48.1260519282651 -1.52091302043498 0.129447558404355 -119.185336343936 108.46013741325 -1.09888609019387 0.272793047660981 KRT20 other 1 1 1 -1.52091302043498 -1.09888609019387 0.309127506366106 31.0686295693115 21.7612886905946 1.42770173269838 0.154524812053859 -4.57567828176149 45.613774821426 -0.100313519318997 0.920169322648749 KSR2 other 1 1 1 1.42770173269838 -0.100313519318997 2.07192174179707e-08 25.8201824896806 11.488678941676 2.24744573512417 0.0254221528756144 -109.70656320829 25.6009287766957 -4.28525715473867 2.54450232901408e-05 ZNF524 other 0.000207088578092617 0.387502259685555 1 2.24744573512417 -4.28525715473867 0.00346857136406595 297.493917221797 116.229152033653 2.55954648224277 0.0110200313444998 -146.138877361586 191.633113640317 -0.762597207682379 0.446362052360224 MCC other 1 1 1 2.55954648224277 -0.762597207682379 1.12178331534566e-12 62.0840325231382 11.5554870632732 5.37268850574546 1.66757781674133e-07 -63.2394919701296 22.0593542936592 -2.86678799063068 0.00447089176882663 ZBTB26 other 1.37968129954363e-08 1 0.0019462300699188 5.37268850574546 -2.86678799063068 0.329772222854481 4.4387238778441 26.7338003998295 0.166034151952164 0.868254333955702 -45.8856685814905 39.6648437574042 -1.15683472402246 0.248362359152806 CDK5R2 other 1 1 1 0.166034151952164 -1.15683472402246 1.39636912385574e-06 120.177386594449 27.2552695894651 4.40932665149275 1.50238408561474e-05 -9.14484315053056 44.9917200145581 -0.203256135741677 0.83908907581825 DSEL other 0.0122936337664259 1 0.152041269464212 4.40932665149275 -0.203256135741677 3.29698807139098e-35 380.922120719692 27.5636606072541 13.8197217759764 3.24637714612902e-33 -15.3724856253668 67.2688434431054 -0.228523114692295 0.819412571889935 POLR1C essential 5.20990055041203e-31 1 5.13771647146379e-29 13.8197217759764 -0.228523114692295 5.28914555903184e-15 377.581651772279 46.3270862566421 8.15034318542198 1.52152169888982e-14 -280.555513104008 227.787823276295 -1.2316528121159 0.219187347776457 ASXL1 ts 6.99753957459913e-11 1 2.21122748499657e-10 8.15034318542198 -1.2316528121159 8.71516319242395e-05 86.6621137706806 22.6423776040223 3.82742993188513 0.000160969130885379 -44.2459673858596 55.2585005281847 -0.800708795261136 0.424004253800926 DLK2 other 0.650761235578296 1 1 3.82742993188513 -0.800708795261136 1.66528590286261e-12 89.6677812321996 28.0846524084535 3.19276806164814 0.00157472014099641 -256.59063974625 55.8656976177471 -4.59299088148749 6.68819742873854e-06 ZNF562 other 2.03631160202039e-08 0.103252391904866 1 3.19276806164814 -4.59299088148749 3.54782274222088e-19 440.090948570543 47.16962242099 9.32996547317511 4.01323262283689e-18 -31.3918631299708 115.034590901664 -0.272890639971119 0.785145881877467 ZNF318 other 5.12660386250917e-15 1 6.07041566530307e-14 9.32996547317511 -0.272890639971119 4.57426776118549e-10 79.3349381057939 30.158055263774 2.63063839534412 0.00900837091088569 -252.264976161383 59.9900889497277 -4.2051108871131 3.54506516300127e-05 ZNF561 other 5.03718365861746e-06 0.537502780014253 1 2.63063839534412 -4.2051108871131 4.13807227872329e-66 496.14246993229 21.7799365983955 22.7797940407614 1.52724089444891e-64 -46.3310948244039 95.9662416726099 -0.482785342187965 0.62964375654721 WIPF2 other 6.60022528456365e-62 1 2.43564377846713e-60 22.7797940407614 -0.482785342187965 0.198829878463405 -54.8684785283233 224.346477843344 -0.244570269414422 0.806982831111318 -847.439632563148 494.296830436908 -1.71443468859409 0.0876451720653671 HOPX other 1 1 1 -0.244570269414422 -1.71443468859409 0.064437246574768 52.0016239565957 33.6968917296152 1.54321723124667 0.123944967261038 -44.9628348204147 59.656593201828 -0.75369430950068 0.451687124800906 LRRC8C other 1 1 1 1.54321723124667 -0.75369430950068 4.83170632369372e-20 1182.96393421733 133.671119620822 8.8498094246011 1.21659263242158e-16 -24.4948699113262 260.809923923044 -0.0939184734341391 0.925244095266937 RSL1D1 essential 7.0658873277697e-16 1 1.81552118536273e-12 8.8498094246011 -0.0939184734341391 4.13188952148545e-05 358.683533208798 83.9516491816258 4.27250133505777 2.67846840322448e-05 109.968382234952 148.627043231089 0.739894839083697 0.460004281353257 LRRC8D other 0.319147146639536 1 0.265516572811643 4.27250133505777 0.739894839083697 5.71123878114132e-15 230.635382514299 40.8700203591756 5.64314332333138 4.18900903711292e-08 -118.000416259372 60.1010534959938 -1.9633668529161 0.0506222440392667 PPID other 7.54350731705951e-11 1 0.000504817479062478 5.64314332333138 -1.9633668529161 0.535348491287834 1.7526631011856 8.18831759202826 0.214044348120046 0.830672253156991 14.751026339869 14.0557558501912 1.04946517975184 0.294892223344356 COL24A1 other 1 1 1 0.214044348120046 1.04946517975184 1.82849023969726e-23 70.200162294384 19.6135729030706 3.57916238113831 0.000408045903346669 -189.981545444766 28.8425692949373 -6.58684541942362 2.31353588950115e-10 ETFDH other 2.7716255053331e-19 3.68708214709799e-06 1 3.57916238113831 -6.58684541942362 0.567706197871712 -8.17158755077809 14.7588467387215 -0.553673853753016 0.58025525333724 -23.0577342351279 21.7180006125052 -1.06168770535218 0.2893157825424 RXFP1 other 1 1 1 -0.553673853753016 -1.06168770535218 3.25280773322316e-11 397.452098430764 60.0067532081339 6.62345614754722 1.85944770239337e-10 91.6390953529681 103.005319832409 0.889654005269497 0.37443497955935 LPAR3 other 3.78041314755196e-07 1 2.46506981906289e-06 6.62345614754722 0.889654005269497 0.000359492097952075 76.2668459447862 18.9075548406835 4.03367048713683 7.23772997683144e-05 48.1539493634667 123.06163794192 0.391299434728745 0.695898880868803 PTGER4 other 1 1 0.689249025693658 4.03367048713683 0.391299434728745 1.86216136152862e-12 457.488945273354 98.9643316253387 4.62276597800231 5.85668065507538e-06 -487.305436300365 156.316301588531 -3.11743197189433 0.00201996033261598 TBCA essential 2.27239550947338e-08 1 0.0612550229714334 4.62276597800231 -3.11743197189433 0.331618929242276 18.5245769670312 17.1812712041036 1.07818430586246 0.281910268937205 -20.894923385024 40.9597660514358 -0.510132879147427 0.610373598764254 MAP6 other 1 1 1 1.07818430586246 -0.510132879147427 0.123290533041691 -57.3300054239387 190.351766870971 -0.301179265978653 0.763507908247035 -576.318847019333 300.66473151923 -1.91681559758356 0.056309020600332 OTP other 1 1 1 -0.301179265978653 -1.91681559758356 0.121314126609018 64.1411181598444 58.6840082147159 1.09299143175704 0.275361093977274 -80.8514297681482 89.7312379618297 -0.901039945559886 0.368361271358511 ECEL1 other 1 1 1 1.09299143175704 -0.901039945559886 3.17596935102321e-08 433.543833943836 98.3592703440348 4.40775772763883 1.54453854036918e-05 -1459.90085470086 445.375055052435 -3.27791338589671 0.00119238069153295 BCL2L1 essential 0.000313944570348644 1 0.156183737202131 4.40775772763883 -3.27791338589671 0.589991219264104 -246.92118536044 356.248302632783 -0.693115401633125 0.488826363421068 -539.977216246204 528.103404434887 -1.02248387666431 0.307457135038523 FGG other 1 1 1 -0.693115401633125 -1.02248387666431 0.722750214678279 149.550762515246 218.896275471603 0.683203778561533 0.495057480436575 243.239018496611 324.492404427902 0.749598496536319 0.454142011361832 FGA other 1 1 1 0.683203778561533 0.749598496536319 0.581292809965004 81.3369464542809 82.1634507759335 0.989940730168375 0.323079670797061 103.518269645198 121.799311755923 0.849908494168189 0.396120698872101 FGB other 1 1 1 0.989940730168375 0.849908494168189 1.02722783946466e-09 313.62644089246 75.5810010951082 4.14954070928227 4.4547260640169e-05 -198.07892926903 112.04147133879 -1.76790724811244 0.0781933505329688 PLRG1 other 1.10827611599842e-05 1 0.432732089858602 4.14954070928227 -1.76790724811244 6.16396174608478e-22 51.414835208776 6.39100490730311 8.04487493821564 2.90309783008763e-14 -56.5816302756489 15.5659814266378 -3.63495424572598 0.00033391948179564 ZNF584 other 9.219437583619e-18 1 4.20049225035379e-10 8.04487493821564 -3.63495424572598 0.708970516136239 3.00671854241792 6.56388168007419 0.458070192146416 0.647266407497003 11.5146670022362 14.6601949566236 0.78543750859423 0.432878217376078 DNAI2 other 1 1 1 0.458070192146416 0.78543750859423 0.620880499481097 3.55631037386002 5.46679053188887 0.650529840701846 0.515897132010678 -2.30037983713919 8.48248087062111 -0.271191868537718 0.786448409720692 NMUR1 other 1 1 1 0.650529840701846 -0.271191868537718 0.000259809784674928 2180.13912042411 788.64800790402 2.76440071942645 0.00609110963140517 -1410.22139781136 1253.13380352584 -1.12535580306232 0.261426672972061 CLSTN1 other 1 1 1 2.76440071942645 -1.12535580306232 0.0573695372882342 45.7349239567562 79.0394169492728 0.578634379174491 0.563318259189322 -229.916681936394 129.867486890148 -1.77039448011245 0.077789839944832 CXXC5 other 1 1 1 0.578634379174491 -1.77039448011245 0.000207691684798343 64.8948417645217 23.9085977867734 2.7142889074165 0.00707438107601137 -111.471941610108 57.7086792141962 -1.93163217609538 0.0544631072046574 ZNF274 other 1 1 1 2.7142889074165 -1.93163217609538 0.0135797182060239 73.9136810987542 64.1970619250512 1.15135613503694 0.250593112475032 -172.812218630153 102.006861843381 -1.6941234688259 0.0913822889845185 PIK3CD other 1 1 1 1.15135613503694 -1.6941234688259 1.64563832873011e-13 123.696894741711 22.2898411419232 5.54947403860406 6.77793904803387e-08 -72.8155802306644 35.4177695628748 -2.05590530203772 0.0407424546394651 SLC25A33 other 2.08337812417232e-09 1 0.000807930334525638 5.54947403860406 -2.05590530203772 0.574631976662678 -131.18868045026 124.638484087667 -1.05255356249347 0.293479798328891 -91.1404447392698 195.115773231378 -0.467109569000304 0.640795448242256 ENC1 other 1 1 1 -1.05255356249347 -0.467109569000304 0.009067963802076 328.491567248348 108.505490205219 3.02741885804178 0.00270227321415858 368.022331467562 172.065774972864 2.13884679580004 0.0333354148314496 SPSB1 other 1 1 1 3.02741885804178 2.13884679580004 0.00167713094210383 66.2364421672101 18.9424489579398 3.49672010806433 0.000552423483788005 20.5726881698458 44.5638558947407 0.461645155177736 0.644715963708873 P2RY6 other 1 1 1 3.49672010806433 0.461645155177736 5.32738997043035e-10 423.76768143055 64.9020116197726 6.52934586855622 3.27933562441529e-10 -38.7977161738632 145.884342385501 -0.265948459851433 0.790482622361604 BPTF other 5.84361405856505e-06 1 4.30937494404413e-06 6.52934586855622 -0.265948459851433 0.107623396591917 1.510590858417 12.9810527047705 0.116368902643917 0.907446367790089 -54.1451960193379 28.8036409397395 -1.8798038807877 0.0612075611374099 ZIK1 other 1 1 1 0.116368902643917 -1.8798038807877 4.0112170416826e-20 922.833475693467 89.600653727536 10.2994056103618 3.64276553614921e-21 1113.2814971583 863.498094823549 1.28926919912405 0.198420299010146 NMRAL2P other 5.87202062731916e-16 1 5.6054876070264e-17 10.2994056103618 1.28926919912405 0.000140996966717789 63.6201164131264 82.8456123843028 0.767935857821975 0.443198871456435 -408.827470967016 132.027227675177 -3.09653908641363 0.00216492264045113 PLEKHG5 other 1 1 1 0.767935857821975 -3.09653908641363 0.000252720499578903 211.446047954987 63.1752315524537 3.34697701550054 0.000932192126451058 -401.097894318632 264.008982752701 -1.51925851210276 0.129858935408272 ATF7IP other 1 1 1 3.34697701550054 -1.51925851210276 6.47095580585125e-05 58.4496176906894 16.5580174086625 3.52998890193887 0.000489277652030477 -81.6647491577112 46.6177660952755 -1.75179456241657 0.0809572271832759 RGS19 other 0.490498450083525 1 1 3.52998890193887 -1.75179456241657 3.76158748670848e-06 119.907406259093 26.1986780102447 4.57684949645948 7.23931150184456e-06 -76.8185982468943 73.7602705290112 -1.04146307620551 0.298602786936734 TCEA2 other 0.0319245929996949 1 0.0752526430616742 4.57684949645948 -1.04146307620551 0.0791908269405075 71.6739271136265 56.1870192654282 1.27563141897665 0.203186299222187 -66.7375721657936 94.0021708859587 -0.709957775834328 0.47834529763026 DEFB4A other 1 1 1 1.27563141897665 -0.709957775834328 0.268776645225241 6.93055601849424 10.2157740749581 0.678417119215966 0.498086146625544 -16.415522520249 18.781364711278 -0.874032466362344 0.382874449954522 ANO5 other 1 1 1 0.678417119215966 -0.874032466362344 8.74876736642431e-16 372.81409850881 50.4160583418353 7.3947490297838 1.75842909263708e-12 -90.7271049856917 83.5761099437179 -1.08556266912625 0.278633687749435 HDAC3 essential 1.1802962054043e-11 1 2.4642625304216e-08 7.3947490297838 -1.08556266912625 5.44792769012774e-21 144.682909225435 17.5952744411072 8.22282765237338 8.33480976115413e-15 -52.9639193953199 31.9643303269706 -1.65696946732623 0.0986828734181452 GPHN other 8.0645673596961e-17 1 1.21579869985955e-10 8.22282765237338 -1.65696946732623 0.183425735889485 -0.417190350970714 7.21904877415315 -0.0577902108743756 0.95395816712761 -18.5785111465216 12.0314307016395 -1.54416474708947 0.123711049854729 VAT1L other 1 1 1 -0.0577902108743756 -1.54416474708947 1.01690027907346e-09 72.6497605587656 38.1779439219505 1.9029249114957 0.058106143400688 -259.393708306903 59.2667849026078 -4.37671300599756 1.71932810943179e-05 TMEM51 other 1.09794527310994e-05 0.263125973867441 1 1.9029249114957 -4.37671300599756 2.03347750945693e-17 254.281782185334 42.0771102488933 6.04323302339952 4.997573986087e-09 -200.44659625481 67.5955055356548 -2.96538349208854 0.00329336212315355 CAMTA1 other 2.8513421637605e-13 1 6.28544880230162e-05 6.04323302339952 -2.96538349208854 0.00155124096474601 29.479710081947 8.29275975648592 3.55487328074231 0.00044713108488493 -0.642305318252017 35.1797496809591 -0.0182578137728951 0.985446817539395 LGALS4 other 1 1 1 3.55487328074231 -0.0182578137728951 0.347652288038293 5.06386547105257 3.50437199133633 1.44501368107372 0.149662812476246 -4.88050008572045 32.783127822224 -0.148872313593333 0.881770236096618 LRRC34 other 1 1 1 1.44501368107372 -0.148872313593333 0.243243859602626 28.8402105938319 18.8749269921934 1.52796408726561 0.12768348117521 46.7508284782724 41.3472984844286 1.13068640979963 0.25918309406186 PAH other 1 1 1 1.52796408726561 1.13068640979963 1.54133378894987e-15 66.5693353738749 10.2345733815086 6.50435859829291 3.74653471072793e-10 -38.6595825440101 18.3598883628215 -2.10565455410367 0.0361544259879814 SPATA5L1 essential 2.06646621084509e-11 1 4.91395492659075e-06 6.50435859829291 -2.10565455410367 0.933558696018067 22.2179849593828 63.8566287408915 0.347935451612014 0.728158762858802 6.13945978220734 114.552950201828 0.0535949512552087 0.957297366119593 GATM other 1 1 1 0.347935451612014 0.0535949512552087 0.772337126754121 -0.471222615718175 23.6253394465249 -0.0199456442429016 0.984101972831505 -19.2914507022986 33.1964716708143 -0.58112955176677 0.561654633450145 SYCE1 other 1 1 1 -0.0199456442429016 -0.58112955176677 0.212335484859062 5.26545200260908 3.01748678770135 1.74497930664352 0.0821346914973805 1.1905965951462 16.0180325126059 0.0743285165771275 0.940804435300492 RASGRP4 other 1 1 1 1.74497930664352 0.0743285165771275 5.17505858215613e-06 9.88004420589994 2.84137809415536 3.47720151226017 0.000589685891575871 -10.6078101066321 5.66080488818278 -1.87390491567312 0.0620155389560707 SLFNL1 other 0.0434135664457078 1 1 3.47720151226017 -1.87390491567312 2.91954018792912e-08 711.854464391484 137.413145247774 5.18039568272682 4.30727505751627e-07 -54.4777195041842 243.827536439102 -0.223427264614104 0.823370081177063 BCL2 ts 0.000289443214231293 1 0.00489564883037299 5.18039568272682 -0.223427264614104 5.92624314967807e-31 419.377082599823 31.7492979921354 13.2090190688218 4.34026839206204e-31 -41.7324426032364 149.991085404112 -0.278232819575904 0.781045809846251 RHNO1 other 9.30123862341974e-27 1 6.8558879521012e-27 13.2090190688218 -0.278232819575904 3.23789856632022e-21 479.341232397095 54.9976766871224 8.71566330199783 2.89821183955342e-16 -206.138397641216 109.570464300249 -1.88133178916126 0.0609947644007796 CTPS1 essential 4.806984211559e-17 1 4.30848172068012e-12 8.71566330199783 -1.88133178916126 0.0437627086090118 -29.0735223899631 22.9286992725693 -1.26799702173883 0.205920377907609 -79.8139390890992 32.0300992530334 -2.4918417660395 0.0133247356922921 KNDC1 other 1 1 1 -1.26799702173883 -2.4918417660395 1.01181878536634e-10 38.672206781983 5.63197857673929 6.8665401075394 4.45649713349173e-11 -25.2626975191516 19.2731221604833 -1.3107734859352 0.191039919330224 METTL18 other 1.15084268647567e-06 1 6.01760807935388e-07 6.8665401075394 -1.3107734859352 0.11138554268798 -7.47005487040711 11.3835853498839 -0.656212839875033 0.512256562581734 -31.4407509121962 15.9248256085198 -1.97432309056969 0.0493832813558282 CFAP46 other 1 1 1 -0.656212839875033 -1.97432309056969 0.157893524541505 126.973280182802 106.673007853681 1.19030373978924 0.234968683660694 -103.87543678228 152.408989299928 -0.681557152628721 0.496101039782409 COL8A2 other 1 1 1 1.19030373978924 -0.681557152628721 2.72904171357449e-09 120.613698088279 43.9606059509274 2.7436768779511 0.00648716559258635 -182.485452076469 60.9363778420117 -2.99468820660124 0.00300508915145973 PWWP2B other 2.87785984712917e-05 1 1 2.7436768779511 -2.99468820660124 0.142445153991243 3.08739717707891 1.85800909958668 1.66166956758485 0.0977482929653137 12.9347736937924 9.12722411578496 1.41716402815425 0.157596435617056 ZNF540 other 1 1 1 1.66166956758485 1.41716402815425 3.63744681534371e-18 85.2346321747185 9.31792967694977 9.14737877723715 1.46706155766758e-17 -60.7412913541707 43.2555849603829 -1.40424158891396 0.161396170707889 FBXL14 other 5.16735694587727e-14 1 2.20822105660124e-13 9.14737877723715 -1.40424158891396 7.72016140398083e-28 416.470949626236 60.5320194347295 6.88017603766398 4.08180956157819e-11 -480.635119331426 94.7875901327122 -5.0706544881929 7.32695440333364e-07 EXOSC10 essential 1.19901826765226e-23 0.0114923279816288 5.51819834629756e-07 6.88017603766398 -5.0706544881929 4.05539794563116e-08 25.1445472226496 4.34475607989411 5.78733230595132 1.98576936166809e-08 -7.55703631777 21.0872990965887 -0.358369096163316 0.720348189142302 ZNF570 other 0.000398037308363698 1 0.000242899308319241 5.78733230595132 -0.358369096163316 0.25235346872002 3.34476442768679 11.4674455812118 0.29167475912568 0.770765235549143 85.7645365750598 51.5631233452329 1.66329211674856 0.0974451088583332 NINJ2 other 1 1 1 0.29167475912568 1.66329211674856 3.27046946565356e-11 138.624923383389 23.4180838397418 5.91956730243383 1.03294420986423e-08 -200.611438859945 80.7656423398934 -2.48387102545032 0.0136367347846955 MLLT3 other 3.80028551908944e-07 1 0.000128178047002052 5.91956730243383 -2.48387102545032 0.00345233857491753 13.7543916419585 4.33833803309703 3.17042875336747 0.00169622113771456 -13.4783349250301 20.3345610242288 -0.662828910295657 0.50800142020171 FAM90A1 other 1 1 1 3.17042875336747 -0.662828910295657 5.81343048413271e-07 647.383414900225 122.817196425541 5.27111376697731 2.77197955962227e-07 28.9302464178748 377.1915504847 0.0766990840083737 0.93891952704555 RRM2 essential 0.00527743219349567 1 0.0031908256710812 5.27111376697731 0.0766990840083737 7.16683759001553e-11 132.66407812002 26.4380440285684 5.01792333716765 9.54727278922323e-07 -238.49696407733 77.3630637176011 -3.08282729013831 0.00226521370549386 TRAPPC12 other 8.20674572432678e-07 1 0.0106022464324324 5.01792333716765 -3.08282729013831 4.4669054847895e-12 3004.67261422195 460.705049110376 6.52190076931866 3.38659737664811e-10 -2331.45749057053 1294.4824689057 -1.80107305164313 0.0728029762852656 RPS21 essential 5.36162665339284e-08 1 4.44694101527663e-06 6.52190076931866 -1.80107305164313 0.130865639778375 41.390884072954 23.4620827106843 1.76416069209854 0.0788315354579094 141.422718524527 109.896920917309 1.28686697811069 0.199238780133618 C3AR1 other 1 1 1 1.76416069209854 1.28686697811069 1.89534160295306e-20 104.439788110653 11.2561092538731 9.27849808091698 5.89596645645621e-18 -67.2190101129008 33.9082276879379 -1.98238052225928 0.0484540514037627 MRM3 other 2.78615215634099e-16 1 8.90290934924888e-14 9.27849808091698 -1.98238052225928 1.03832015149985e-21 124.403919223804 90.2741906072203 1.37806740095938 0.169358242406934 -967.386989456266 130.136706160127 -7.43362128949185 1.50207808050316e-12 PTEN ts 1.54927749805293e-17 2.39746682429109e-08 1 1.37806740095938 -7.43362128949185 1.13242212976732e-07 989.510561849844 183.149417155414 5.40275026379243 1.45351552754957e-07 -121.443894480725 535.932235150417 -0.22660307873931 0.820905786123248 RPS7 essential 0.0010808969228629 1 0.0017022120343133 5.40275026379243 -0.22660307873931 0.693984741101015 1.22505748628443 3.20693333486398 0.382002791566103 0.702756480078449 9.54486389116631 11.4916122579159 0.830593973843085 0.406928830551927 PRND other 1 1 1 0.382002791566103 0.830593973843085 1.312367314911e-16 119.714047694938 14.3050410269013 8.36866161165212 3.29786942542002e-15 -29.0397681722913 41.8594431286673 -0.693744732413878 0.488445409029188 RNASEH1 other 1.80555495185455e-12 1 4.83665529932099e-11 8.36866161165212 -0.693744732413878 1.80725637136869e-07 1768.09958247359 310.376858715197 5.69662180934695 3.15860077541966e-08 677.969292874793 1112.19353249708 0.609578524838774 0.542648039234362 PRNP other 0.00170207405055503 1 0.000382727655957601 5.69662180934695 0.609578524838774 0.374905437749566 16.2752550112864 14.9800854561054 1.08645942367793 0.278237664386463 -33.0399034362636 54.2933759904095 -0.608543912283146 0.543334641828835 ADRA1D other 1 1 1 1.08645942367793 -0.608543912283146 0.0432747463911378 21.9228158157141 13.487084751336 1.62546734301069 0.10522107946224 -22.173113320463 24.1764729831447 -0.917135983231369 0.359883853271588 FRMD5 other 1 1 1 1.62546734301069 -0.917135983231369 0.125534562484773 -307.468675391746 360.457848341808 -0.852994814251304 0.394459544295532 -1545.41232339604 755.581850098138 -2.04532748264839 0.0418449172580394 AQP4 other 1 1 1 -0.852994814251304 -2.04532748264839 1.8178494604168e-05 1489.79242888737 367.251771352277 4.05659698631739 6.51618074809785e-05 -324.224046358676 851.376967668779 -0.380823135545303 0.703632844503754 CYP4F11 other 0.145664277263198 1 0.623142364940597 4.05659698631739 -0.380823135545303 0.00484782044412618 78.7154108883442 40.0589314866156 1.96499027725301 0.0504292564333698 -129.907234160878 79.3780700030464 -1.63656327441436 0.102873997681152 TLN2 other 1 1 1 1.96499027725301 -1.63656327441436 0.00179584036395747 14.8305273720593 11.0716026807731 1.33951043942482 0.181518601300007 -64.3478018488805 28.7253675275642 -2.24010369187214 0.0258889858767713 LGALS9C other 1 1 1 1.33951043942482 -2.24010369187214 9.48780501117204e-16 166.310925818069 28.9750843642085 5.73979090889223 2.51769171734588e-08 -235.442318130852 75.2761246057158 -3.12771571815181 0.00195227580519485 TVP23B other 1.27895611550599e-11 1 0.000306503789669688 5.73979090889223 -3.12771571815181 0.0510745448835419 9.02676225675735 3.7096635265921 2.43331024284292 0.0156035962443166 14.1735722956529 9.6383259483631 1.47054295233293 0.142566368578572 FBXW10 other 1 1 1 2.43331024284292 1.47054295233293 0.000403959903945546 269.721162091802 74.8000573475087 3.60589512436764 0.000370207704735529 -164.10293598769 231.695154032025 -0.708270903089356 0.479385793695654 ZNF217 other 1 1 1 3.60589512436764 -0.708270903089356 0.56588365941637 56.9223907225692 88.7263363269129 0.641550108784366 0.526382741085552 -20.3746654772524 102.568705373763 -0.198644073774808 0.843976512881301 SRGAP2C other 1 1 1 0.641550108784366 -0.198644073774808 0.642356953457799 -423.044811287745 837.457136623598 -0.505153986738173 0.613859739286489 -1154.55738044106 1226.13047848636 -0.941626850240556 0.347219253647205 SCG2 other 1 1 1 -0.505153986738173 -0.941626850240556 2.78030282019074e-17 91.2667764175608 12.6599652725806 7.20908584285216 5.57500710460249e-12 -59.3835907275635 31.7133018153158 -1.8725136560484 0.0622083304564782 ATPAF2 other 3.88658531234463e-13 1 7.71413733063846e-08 7.20908584285216 -1.8725136560484 0.419887822219202 -16.9466321243523 23.7405531491224 -0.713826338329391 0.475944393367133 -70.3216321243524 53.637062486736 -1.3110641944969 0.190937780373158 CYP4F22 other 1 1 1 -0.713826338329391 -1.3110641944969 3.22532486261504e-21 216.933109313856 30.6536330403851 7.07691349433374 1.26195983698126e-11 -218.05257212326 57.4004489097094 -3.79879558897275 0.000179540854881284 PPIH essential 4.7889623560108e-17 1 1.73166128830569e-07 7.07691349433374 -3.79879558897275 0.152082209610424 18.9371138731752 14.9384258069246 1.26767800824081 0.205997086894549 -26.2616536999772 37.4208614368603 -0.701791799857098 0.483409061085623 DRC3 other 1 1 1 1.26767800824081 -0.701791799857098 7.88692326149657e-17 28.8962898368502 7.5836902772539 3.8103204087224 0.000171781286467019 -59.4380659291633 12.7733488801846 -4.65328759800571 5.11598363564304e-06 ZNF57 other 1.09147131015851e-12 0.0791596147943048 1 3.8103204087224 -4.65328759800571 0.000767185274142615 19.9812268493042 6.17656054296224 3.23500866061637 0.0013667177347756 -27.9701018856145 22.571658096653 -1.23916912819807 0.216351052969261 C20orf196 other 1 1 1 3.23500866061637 -1.23916912819807 6.66064670277237e-07 161.333995588029 81.4356340147223 1.98112285291304 0.0485957319153442 -355.514512215559 122.752245118029 -2.89619560011896 0.00408749945288973 JMJD1C other 0.00601722823128456 1 1 1.98112285291304 -2.89619560011896 0.159515629150511 -90.8304776561238 330.961042521109 -0.274444620322135 0.783950516398297 -998.657575222916 552.301235653257 -1.80817552226135 0.0716795423320128 SYNPO other 1 1 1 -0.274444620322135 -1.80817552226135 8.10682156899558e-06 28.1610661015403 10.1237394053594 2.78168619064139 0.00578738679042384 -29.4405349773375 17.0516002986812 -1.72655554092565 0.0853871202643785 ZNF556 other 0.0669055984089206 1 1 2.78168619064139 -1.72655554092565 0.522266618328645 -26.6852731104869 46.4681742286737 -0.574269885861375 0.566285524359931 182.851363921223 206.43383293825 0.885762577377127 0.376570299423581 MAL other 1 1 1 -0.574269885861375 0.885762577377127 1.1348151730077e-11 24.4599463614962 8.10216830870473 3.01893831743993 0.00277833427722323 -52.0602658559936 13.6223073850121 -3.82169219828888 0.000164436416598797 ZNF554 other 1.34362116484111e-07 1 1 3.01893831743993 -3.82169219828888 1.46570197742045e-11 29.6894867821196 16.6075179891271 1.78771366085873 0.0749436423820022 -112.746740096693 24.6567934481921 -4.57264405988522 7.34218782606369e-06 RAB33B other 1.72850234197193e-07 0.113297300343989 1 1.78771366085873 -4.57264405988522 5.68368584077345e-14 259.444537990132 57.5023715084342 4.51189283475165 9.58263335005885e-06 -296.503429444118 96.6796726764464 -3.06686422528976 0.00238196086271752 THOP1 other 7.30239956822572e-10 1 0.0985478013720052 4.51189283475165 -3.06686422528976 0.272458886870023 8.74473490673262 15.0586617192366 0.580711292263225 0.561917640943543 91.3795701115684 57.4728376906135 1.58996099346061 0.113009474382363 GAP43 other 1 1 1 0.580711292263225 1.58996099346061 0.0135818801257307 11.5609399982235 7.76836412521411 1.48820778890882 0.13785028255829 -19.7188495588322 13.7442321409944 -1.43469997861994 0.152517160849947 EPHX4 other 1 1 1 1.48820778890882 -1.43469997861994 0.516756769842124 250.618953738457 314.24272025152 0.79753304559565 0.425834644726584 -398.913992324879 750.521524395494 -0.531515725210124 0.595493656064424 LAMB2 other 1 1 1 0.79753304559565 -0.531515725210124 3.62588299294724e-08 314.60501623582 58.7443961732545 5.355489829327 1.81287925618931e-07 -132.396638974403 140.302164296296 -0.943653575398891 0.346181067282736 USP19 other 0.000356786886506008 1 0.00211037274212998 5.355489829327 -0.943653575398891 2.13452632850042e-61 643.762314872184 29.6929349319052 21.6806562351793 9.91009232623895e-61 83.3683753022203 132.090835218358 0.631144281618064 0.528488132298249 ORMDL3 other 3.40350223079391e-57 1 1.58006512049554e-56 21.6806562351793 0.631144281618064 7.24598845953209e-05 55.9368947664631 19.4272551347994 2.87929995145146 0.00430842455527404 -45.306949321847 30.1459245746724 -1.50292120613585 0.134041181948995 SERF1A other 0.545478011233576 1 1 2.87929995145146 -1.50292120613585 0.000443995184342091 100.664755846372 30.5622824412218 3.29375778919566 0.00112006054229956 -102.589645355033 93.0450980849611 -1.10257979696423 0.271187877103536 KLF11 other 1 1 1 3.29375778919566 -1.10257979696423 0.238153105204563 -42.2548308352154 33.6094691225283 -1.25722993960926 0.209756803940959 -329.540218303308 258.824394931904 -1.27321931300181 0.204035340815383 LRRC15 other 1 1 1 -1.25722993960926 -1.27321931300181 1.58798545616374e-10 256.087766261223 40.1391985269439 6.37999201925573 7.77914450017621e-10 40.8245069352016 62.2853430855271 0.655443237731603 0.512746756928824 SMN1 other 1.78823042218598e-06 1 1.00918841600786e-05 6.37999201925573 0.655443237731603 0.00532169439897311 104.638543191801 35.0845351373814 2.98246913581911 0.003123586205787 -108.220292669178 137.669808987487 -0.786085877979349 0.432514250902144 EIF2AK3 other 1 1 1 2.98246913581911 -0.786085877979349 1.42645230257459e-08 -0.545153633288659 60.1790623140642 -0.00905885888423445 0.992778840223766 -555.124190061682 106.074632063774 -5.23333599430192 3.33920236353013e-07 MOB3A other 0.00014381492114557 0.00525423491901466 1 -0.00905885888423445 -5.23333599430192 0.147762760732189 34.5949594959495 40.5178652164684 0.853819896757256 0.393973028458839 -263.151215121512 163.332736392994 -1.61113577677622 0.108336051483446 KRCC1 other 1 1 1 0.853819896757256 -1.61113577677622 2.44409433112001e-12 58.7433923261856 9.47628239770916 6.19899131967474 2.09034592502533e-09 -55.3863757218073 23.3566289282975 -2.37133431762939 0.0184181994781561 NME6 other 2.96795004718478e-08 1 2.66853560788734e-05 6.19899131967474 -2.37133431762939 1.11771477429816e-12 1147.19778665709 163.958877448249 6.99686289947419 2.02307944611737e-11 -569.689745393235 459.609005226409 -1.23950953726983 0.216221329757009 CYCS essential 1.37490094386416e-08 1 2.7596826724487e-07 6.99686289947419 -1.23950953726983 0.846684709347581 -29.3184126171154 57.1563945944243 -0.51295070000751 0.608411529108843 -78.3416944093678 236.363028168782 -0.331446483049056 0.740568234584938 CD8B other 1 1 1 -0.51295070000751 -0.331446483049056 0.290664744370476 6.17719632972249 7.47413345857139 0.826476589421673 0.409260851848177 -11.777429801549 14.5703965865698 -0.8083122330661 0.419619854927171 SLFN12 other 1 1 1 0.826476589421673 -0.8083122330661 0.187701502456457 223.82175081937 125.131856115568 1.78868721177328 0.074782085995424 136.879379677975 216.989893709509 0.630809930075451 0.5286964300343 CALB2 other 1 1 1 1.78868721177328 0.630809930075451 0.393701879416723 -11.6189429987398 10.5151712185884 -1.10496945386873 0.27016015889777 4.15900632997806 20.5548030913418 0.202337444513392 0.839805872324418 CCL11 other 1 1 1 -1.10496945386873 0.202337444513392 0.272617566517096 6.28881869908606 10.666756961731 0.589571762218673 0.555967180654167 -20.5456018866322 19.7261302272561 -1.04154244395304 0.298548736356418 FRMD3 other 1 1 1 0.589571762218673 -1.04154244395304 0.0392209651754695 162.409637660653 63.5903833023628 2.55399683452795 0.011197021307817 154.940001554471 270.370522452248 0.573065436827846 0.567075577453869 SNTB1 other 1 1 1 2.55399683452795 0.573065436827846 2.62203525494722e-11 66.9439761655367 9.2832670132678 7.21125182221509 5.54270095646884e-12 -2.77991495220592 39.3894874475968 -0.0705750476165569 0.943788021852296 MTBP essential 3.05807971784494e-07 1 7.67054385365723e-08 7.21125182221509 -0.0705750476165569 1.14876842884746e-17 66.9819859342984 10.0880607655005 6.63972863480025 1.77043626775347e-10 -61.3192391230781 20.1820505201296 -3.0383056995085 0.002616769757239 TEFM other 1.61712131728857e-13 1 2.34883779642853e-06 6.63972863480025 -3.0383056995085 5.98623991480795e-09 191.286477993635 30.0061926545623 6.37490001466585 7.84927642616085e-10 127.889322582133 127.318167971235 1.00448604170166 0.316040442912362 MRPL13 essential 6.18378583199661e-05 1 1.01805115247306e-05 6.37490001466585 1.00448604170166 4.38389030824207e-14 246.544575125347 57.4131006826206 4.29422156605415 2.44440194857213e-05 -357.018980544137 96.1845046302955 -3.71181389264738 0.000249739352600223 MALT1 other 5.65254955070882e-10 1 0.24314466182447 4.29422156605415 -3.71181389264738 0.67398412461048 15.5151480328157 43.0640991780367 0.360280333942958 0.718917109899773 78.6644068977472 88.935960690365 0.884506180482171 0.377204214747798 ISG20 other 1 1 1 0.360280333942958 0.884506180482171 7.70863766808152e-05 104.003766394534 24.578268919867 4.23153342221212 3.18666481440968e-05 6.25280741679244 45.6615526273147 0.136938125337683 0.891182136823023 MBOAT1 other 0.578841602496241 1 0.313567817737912 4.23153342221212 0.136938125337683 0.0942180028770843 71.3099897323255 52.033790048324 1.3704554226417 0.171683085801111 -112.186448406023 96.0495519272335 -1.16800595270881 0.24383470214678 ID4 other 1 1 1 1.3704554226417 -1.16800595270881 0.291204011473028 -30.910925872408 22.2903687143794 -1.38673910102112 0.166652622556407 -67.8281554800946 57.9359039277387 -1.17074475207454 0.242722299647006 CXCR6 other 1 1 1 -1.38673910102112 -1.17074475207454 0.00613401161629317 170.124730181572 76.8250451980802 2.21444360680732 0.0276366953390604 -424.247124582047 258.428019291166 -1.64164522773382 0.101832108534118 CEBPB other 1 1 1 2.21444360680732 -1.64164522773382 0.0240813017104195 -256.459971078266 132.183879073487 -1.94017585862863 0.0533917544046407 -652.394132769283 241.70252492021 -2.69916142988018 0.00738673216458169 TPSAB1 other 1 1 1 -1.94017585862863 -2.69916142988018 1.63912821015945e-30 316.705767652391 23.9430574185047 13.2274572172066 1.39220557442889e-30 -111.414748167983 154.254746246725 -0.722277601687401 0.470804330342047 PAIP1 other 2.57064477199306e-26 1 2.19801416090832e-26 13.2274572172066 -0.722277601687401 0.145264657047739 101.44743189739 51.4662094575336 1.97114636898016 0.0497244809235516 90.457281446732 233.626381322827 0.38718778647578 0.69892108196425 CLEC7A other 1 1 1 1.97114636898016 0.38718778647578 1.49238629736689e-21 35.9892469433743 3.32778568943285 10.8147730359126 1.38505892107259e-22 29.173581094201 21.4394815212787 1.36074097991811 0.174830882028022 C5orf34 other 2.2221631967793e-17 1 2.14490224517301e-18 10.8147730359126 1.36074097991811 7.25923401306544e-07 35.0906365910462 9.93252461955791 3.5329020500941 0.000482744010620989 -56.4311770649778 22.314180913501 -2.52893786618153 0.0120065012269681 SERHL other 0.0065340365351602 1 1 3.5329020500941 -2.52893786618153 0.499074927264257 -19.2209227748042 17.4875936740284 -1.09911764494791 0.272692229526425 -28.9829674126138 30.4111607449208 -0.953037197616816 0.341420491559628 NEGR1 other 1 1 1 -1.09911764494791 -0.953037197616816 3.10772538141642e-34 287.34990529262 19.8601986165786 14.4686320031438 7.59144957926699e-35 41.2979005221735 125.969008936796 0.327841751481068 0.743306805854345 ZNF131 essential 4.9046121969514e-30 1 1.2033965873054e-30 14.4686320031438 0.327841751481068 0.307860574845686 26.9374116234247 31.9736294023945 0.842488392056217 0.400271497506312 -113.379050425926 112.24832575146 -1.01007342129067 0.313378026338162 MACROD2 other 1 1 1 0.842488392056217 -1.01007342129067 2.71104566004566e-18 263.724814503174 38.7433463354827 6.80697047228584 6.39272943599889e-11 -166.615379571855 69.6338315929892 -2.39273605602696 0.0174044481473199 DPAGT1 essential 3.86215564730105e-14 1 8.60205672908011e-07 6.80697047228584 -2.39273605602696 1.35258009393027e-07 1539.60342176732 539.450268384628 2.85402290442386 0.00465149716718623 -2555.88898931494 948.945449330849 -2.69339927929179 0.0075154851261516 BSG other 0.00128386902515861 1 1 2.85402290442386 -2.69339927929179 9.14437138247225e-10 74.4776638874015 16.075678651942 4.63294057438778 5.60471006137312e-06 -50.4711837921124 28.8929895290728 -1.74683148454843 0.0817994624877383 HINFP essential 9.89969645866446e-06 1 0.0587261520230675 4.63294057438778 -1.74683148454843 5.66621766944541e-07 711.32215179379 147.469071021014 4.82353450027789 2.35156304699289e-06 -264.439426475334 374.424667732439 -0.706255354586575 0.480633854405202 CERS6 other 0.00514889199622505 1 0.0253851230922882 4.82353450027789 -0.706255354586575 0.0435259747853498 40.2072463057408 18.0741474293152 2.22457222189784 0.0269492825033064 -32.2816300510003 63.9584186734805 -0.504728395737924 0.614167483586763 SPTLC3 other 1 1 1 2.22457222189784 -0.504728395737924 2.99392093380822e-14 177.403777122244 29.48233247812 6.01729110998602 5.85141247065084e-09 -136.832719192914 57.842999099499 -2.36558825308385 0.0187190282004435 COPRS other 3.87892396184193e-10 1 7.33591581445495e-05 6.01729110998602 -2.36558825308385 5.2708570665909e-16 106.309696992951 14.3810307459068 7.39235586595271 1.82986319623132e-12 -130.867486488561 47.6990966602671 -2.74360513408993 0.00648543730340835 TP53RK essential 7.14886343941724e-12 1 2.56254042000234e-08 7.39235586595271 -2.74360513408993 0.851570138793585 2.76782174292285 4.95025668531851 0.559126913788465 0.576536864361228 1.517278566331 12.1187998467503 0.125200398184467 0.900457726825296 B3GALT1 other 1 1 1 0.559126913788465 0.125200398184467 0.0357902887761656 2.70038661186059 8.15128067679063 0.331283723249707 0.740687158903436 95.854620809558 36.9770292692282 2.59227479069896 0.0100536171609843 CLEC12A other 1 1 1 0.331283723249707 2.59227479069896 7.39861751597913e-05 54.0153952348452 36.905153365941 1.46362744246701 0.144454690730501 -324.735550971025 99.0046491451775 -3.28000304808759 0.00117390256683506 BPGM other 0.556450023376791 1 1 1.46362744246701 -3.28000304808759 2.76124253661009e-24 216.183161878394 20.0074277936081 10.8051451745066 7.04471575868068e-23 -126.608520091765 87.8648657845085 -1.44094592259751 0.150750127330803 POP7 essential 4.21061874407673e-20 1 1.09270586132896e-18 10.8051451745066 -1.44094592259751 4.3862214944773e-11 8.77201729169074 9.7611609753955 0.898665365093553 0.369625760019821 -88.1064081821333 15.8067857887179 -5.57396104178367 5.9932423659823e-08 ALG14 other 5.07091066976521e-07 0.000948490536840358 1 0.898665365093553 -5.57396104178367 1.75165818196594e-09 98.734882392152 55.4944010444275 1.77918637797545 0.0763341262688612 -591.65254102784 116.336851320224 -5.08568466752878 6.86070207729834e-07 SUCLG2 other 1.86814345106668e-05 0.0107637554890734 1 1.77918637797545 -5.08568466752878 0.724417449437942 -24.8792725711662 31.0694623328348 -0.800762893951768 0.423967809712848 -13.2698490238939 60.9105808756834 -0.217857863660458 0.827703204645008 STARD5 other 1 1 1 -0.800762893951768 -0.217857863660458 0.000468678788404193 23.5368497587413 7.98645171449974 2.94709723418338 0.00348795567926528 -25.1884142528105 18.711493127991 -1.34614667469431 0.179384327567317 CSDC2 other 1 1 1 2.94709723418338 -1.34614667469431 0.50425385860444 -23.4370585890414 29.4831675157472 -0.794930143666668 0.427349775439336 -79.7095172451033 74.4973808598455 -1.06996402189043 0.285587551350229 RCAN2 other 1 1 1 -0.794930143666668 -1.06996402189043 0.201517512581798 -79.5794783355283 51.351870787139 -1.54968995512154 0.122378661617563 31.049348083892 100.673524542846 0.30841622189037 0.758001709160455 IL16 other 1 1 1 -1.54968995512154 0.30841622189037 2.52734356266337e-26 1087.29813399983 100.744071923569 10.7926760675777 7.74705756226496e-23 -1273.75658780426 438.592036505518 -2.90419451742196 0.00398419733222527 GNB2 other 3.89817471105199e-22 1 1.20110380445356e-18 10.7926760675777 -2.90419451742196 0.00016250042324912 30.2651276496367 8.62740140923866 3.50802358833417 0.000528637035718074 -3.70179592999526 13.6507049984316 -0.271179835064971 0.786459930648673 CFAP53 other 1 1 1 3.50802358833417 -0.271179835064971 9.08583513837187e-05 39.6610188939036 19.9262627552027 1.99038923561058 0.0475525241913273 -82.8713014464561 35.8136856057443 -2.31395624451352 0.0214183549690348 C2CD2L other 0.677076434511472 1 1 1.99038923561058 -2.31395624451352 5.8642226825515e-08 -92.2463370691221 195.102892244048 -0.472808660128595 0.636730262409675 -1556.50102005669 301.157446758982 -5.16839625520657 4.58776242453892e-07 GNG12 other 0.000569650591383052 0.00721104497889027 1 -0.472808660128595 -5.16839625520657 0.0228885554753923 -26.6740540234036 25.5941623599952 -1.04219288946515 0.298251093360927 -128.881945045467 47.3700670560767 -2.72074651895461 0.00693497599376295 PRSS27 other 1 1 1 -1.04219288946515 -2.72074651895461 0.00300738858719638 -60.846797212299 203.824558507556 -0.298525347768843 0.765531850024421 -896.839576488724 304.174756841155 -2.94843525413606 0.00347336802646439 SYNPO2 other 1 1 1 -0.298525347768843 -2.94843525413606 2.75811872684693e-14 17.3625628073192 2.54449566389138 6.82357728240971 5.82879091546734e-11 -12.0260556811595 6.05080602531053 -1.98751300749926 0.0478757107184824 DNAJB7 other 3.57590092935705e-10 1 7.85138136313451e-07 6.82357728240971 -1.98751300749926 2.61703869180015e-13 61.7504859865692 11.1230847741308 5.55156121170483 6.74549475698504e-08 -99.9502673744286 28.9137499428057 -3.456842075903 0.0006343704700324 CLP1 essential 3.29249637815377e-09 1 0.000804197884927757 5.55156121170483 -3.456842075903 5.25456861312125e-28 191.466860969412 16.8891544445813 11.3366753556358 1.26361337036839e-24 -65.8155119779684 41.2178158194261 -1.59677340173249 0.111485922123348 RSPH9 other 8.16770145223567e-24 1 1.97186866445986e-20 11.3366753556358 -1.59677340173249 6.74566863236506e-08 113.212916666667 46.2085272365513 2.45004382171944 0.0149120644968452 -248.552525568182 73.9689151129806 -3.36022943135695 0.000889884919808114 COPS9 other 0.000652913266926615 1 1 2.45004382171944 -3.36022943135695 3.61556920220955e-25 553.55887637278 51.0460583855567 10.8443020652385 5.54269913552859e-23 -111.61970870269 124.577404970004 -0.895986786123583 0.371057940603662 GTPBP2 other 5.5437522577479e-21 1 8.60559467782169e-19 10.8443020652385 -0.895986786123583 0.000443024292712811 37.325406215491 37.2257923734604 1.00267593610987 0.316918327151272 -162.875492979965 61.0364445261481 -2.66849575273325 0.00808193871181861 FGGY other 1 1 1 1.00267593610987 -2.66849575273325 1.53462336513753e-07 79.9757848448741 16.9845371044464 4.70874091846383 4.06627305608797e-06 0.70851299133029 25.6194992187682 0.0276552240650844 0.977958432767858 IL17D other 0.00145144677874707 1 0.0431178673408882 4.70874091846383 0.0276552240650844 0.525921391936591 4.3194132862952 5.7069034613604 0.75687512773618 0.449784628124527 -5.23829620991946 10.4986739450416 -0.498948365988015 0.618222024097538 FUT9 other 1 1 1 0.75687512773618 -0.498948365988015 5.92852588683577e-26 575.918157113195 67.5304559668619 8.52827289357865 1.16961780128613e-15 -504.330353897518 122.064486794298 -4.13167143976456 4.83850542776729e-05 ZNF24 other 9.12992986572709e-22 0.730807859809971 1.72471840977653e-11 8.52827289357865 -4.13167143976456 0.00461525348402304 68.3099010897292 29.5430880592955 2.31221262153183 0.0215184777601434 -72.1824246334523 54.3487814301067 -1.32813326691197 0.185255680037211 MANEA other 1 1 1 2.31221262153183 -1.32813326691197 0.00419515924596844 -48.4322228208692 38.0346823312979 -1.27336998371656 0.203977937662666 -197.822552794578 59.8648344844303 -3.30448675751418 0.00107966636385462 C2orf54 other 1 1 1 -1.27336998371656 -3.30448675751418 1.06823699780256e-13 184.117539974057 95.684709477293 1.92421068088993 0.0553791429008249 -739.556635488497 146.405301141662 -5.05143345030179 8.08538497203957e-07 AFF1 other 1.36050664040134e-09 0.0126754580206664 1 1.92421068088993 -5.05143345030179 4.20172978221852e-14 310.999461832601 49.6919996531905 6.25854189815508 1.50556210457569e-09 -389.817221356748 118.2590084833 -3.29630043711888 0.00110986412759024 FIBP other 5.422332283953e-10 1 1.93314174227518e-05 6.25854189815508 -3.29630043711888 0.036724166355744 -3.82787904913355 7.08609260927871 -0.540196023422164 0.589510464448103 46.5825332792517 20.7092502708072 2.24935874887353 0.0253016893318838 CARNS1 other 1 1 1 -0.540196023422164 2.24935874887353 2.61637676663985e-08 73.2470136162395 14.4535647987689 5.06774727453246 7.46166416680927e-07 4.64916496918867 23.6824232608588 0.196312890702895 0.844512404277983 BANP essential 0.000259989359301001 1 0.00834437903774281 5.06774727453246 0.196312890702895 5.94504464574975e-18 1170.80372044241 143.316779052251 8.16934156757424 1.23299636042975e-14 -989.133597293197 418.846211734898 -2.3615674908366 0.01891350669686 PPP1CA essential 8.4169942094525e-14 1 1.79437960333342e-10 8.16934156757424 -2.3615674908366 0.266054527748489 -22.0874729108001 20.5957708275272 -1.07242759184712 0.284478582129865 43.5058554653235 50.9422732609239 0.854022655064658 0.393843943000611 CTSW other 1 1 1 -1.07242759184712 0.854022655064658 0.00289161239667019 146.931681086764 74.2769046949116 1.97816106756573 0.048919499491677 -185.358793563514 121.20549592133 -1.5292936360231 0.127353760997282 NIPAL4 other 1 1 1 1.97816106756573 -1.5292936360231 0.840346780509658 42.6851675472901 87.7998198057488 0.486164637259258 0.627240452199814 -37.8472638349406 237.436953672711 -0.159399214189339 0.873472221575665 MUCL1 other 1 1 1 0.486164637259258 -0.159399214189339 0.0426989026480003 26.237990111764 23.3674516173756 1.12284345513543 0.2625164203288 261.964098421248 106.812518426261 2.45255988980447 0.014827075787023 PDE3A other 1 1 1 1.12284345513543 2.45255988980447 0.935879115266704 -8.95742388174271 26.0121260222609 -0.344355700648115 0.730846852023734 -3.35167976127971 45.5114569150472 -0.0736447476848748 0.941347593173688 RASGRP1 other 1 1 1 -0.344355700648115 -0.0736447476848748 0.169726147076321 -16.1028920030652 10.1117685055498 -1.59249017560353 0.112494291781976 -111.059349915846 108.400394121214 -1.02452902331386 0.306541406735478 KLHL6 other 1 1 1 -1.59249017560353 -1.02452902331386 7.83602954851554e-11 154.389732856091 32.0330268155683 4.81970479233816 2.40210149963048e-06 -62.6439736144738 50.2050878481638 -1.24776145804045 0.213199496525905 CHCHD1 essential 8.95893258281782e-07 1 0.0259042625720151 4.81970479233816 -1.24776145804045 2.43122159410419e-17 225.46925566343 38.2031165778708 5.90185502807993 1.06663672536128e-08 -211.82642519293 72.1639696434918 -2.93534884845451 0.00361631669927531 MRPL52 other 3.40395335390527e-13 1 0.000132284286679306 5.90185502807993 -2.93534884845451 0.00674296234984181 -36.5832709273232 28.898570662927 -1.26591973540943 0.206641151937971 -165.142322234197 51.78840669315 -3.18878939861342 0.00159832572903915 SMPDL3A other 1 1 1 -1.26591973540943 -3.18878939861342 0.719738609731186 -72.7604904921988 90.789531291456 -0.801419386764101 0.423588433861878 -88.12899621601 226.375247781244 -0.389304913323265 0.697355216138601 RND1 other 1 1 1 -0.801419386764101 -0.389304913323265 3.31269096457437e-09 208.22236100952 40.1194835532694 5.19005586732065 4.1573117280994e-07 -251.163785793122 117.250009483683 -2.14212166718907 0.0330849914001077 RAD9A essential 3.47004378539166e-05 1 0.00473102074657712 5.19005586732065 -2.14212166718907 0.246261032886244 4.15244165933052 80.6723171932474 0.0514729439267687 0.958986302655371 -312.936774649683 197.319943381499 -1.58593586277617 0.113911449076902 EFEMP2 other 1 1 1 0.0514729439267687 -1.58593586277617 0.000190281165805183 3.95146169679032 7.79686001549085 0.506801672588649 0.612709149452275 -36.8752283398727 12.2145301598866 -3.01896412364461 0.00277994641706236 AGAP5 other 1 1 1 0.506801672588649 -3.01896412364461 3.3694055453981e-16 171.783223601104 52.5682842295888 3.26781111688658 0.00122416419633662 -396.295387403092 82.6062861056547 -4.79739988426818 2.66200001856844e-06 WASHC2C other 4.59249975837761e-12 0.0414207202889249 1 3.26781111688658 -4.79739988426818 8.87302062963482e-07 152.219964539618 46.6824629864068 3.26075264246324 0.00125550900880549 -426.858565862783 135.816211925385 -3.14291320462753 0.00186135073563562 TMEM134 other 0.00793248044289353 1 1 3.26075264246324 -3.14291320462753 1.83477462830845e-16 108.223800332023 12.3431590113143 8.7679175349536 2.31391638353077e-16 358.941313411405 133.649111451173 2.68569921276685 0.00769826664495674 ZMAT3 other 2.51510906048523e-12 1 3.44403314524719e-12 8.7679175349536 2.68569921276685 7.91093071192291e-08 18.3500048324002 9.8044464716156 1.87160028722931 0.0623431258071838 -51.8485248744286 15.4067975055953 -3.36530189713979 0.000875598382118777 ZFAND4 other 0.000762297283400892 1 1 1.87160028722931 -3.36530189713979 0.207602727571809 48.3641081628243 28.2345307541388 1.71294180816994 0.0878627613519605 6.31527660557352 52.5702620729056 0.12013020967663 0.90446868673539 THEMIS other 1 1 1 1.71294180816994 0.12013020967663 0.389743450617612 54.5605683658229 84.0513298087688 0.649133910075635 0.516801574749165 -127.097053987222 163.853270179153 -0.775676029219665 0.438616666011542 SLFN11 other 1 1 1 0.649133910075635 -0.775676029219665 0.965487490572467 -0.207444353148576 6.63948790986843 -0.031244029052338 0.975097924831969 2.56786100058166 12.0615785484507 0.212895931512339 0.831568194518181 FAM71D other 1 1 1 -0.031244029052338 0.212895931512339 0.0013437792569179 1121.45238630078 313.427657653135 3.57802624917637 0.000411776935356022 2089.5235812104 830.603225731378 2.51566995706102 0.0124746932133727 CCL19 other 1 1 1 3.57802624917637 2.51566995706102 1.21741352851155e-09 304.554960150105 83.3987093708291 3.65179464343883 0.000313323661549961 -1021.24477992185 242.63708599759 -4.20893935369795 3.50847832642355e-05 CORO1B other 1.30908476720847e-05 0.532025653418867 1 3.65179464343883 -4.20893935369795 1.3386132179876e-19 65.0016348036542 10.9461291760854 5.9383215525783 9.26477969547627e-09 -54.2866825511957 20.1072892954024 -2.69985087266877 0.00739577841608565 FUT10 other 1.94580817366678e-15 1 0.000115235329852334 5.9383215525783 -2.69985087266877 3.32800269143975e-07 85.8268762994468 29.5270744503958 2.9067179155738 0.00395317500892589 -88.8607536452459 46.355380823592 -1.91694582304071 0.056292395219962 LRRC20 other 0.00308272889308064 1 1 2.9067179155738 -1.91694582304071 3.10071346514078e-10 160.11776728469 28.0195400546208 5.71450377031741 2.87582455206296e-08 -135.806219218535 68.48670100398 -1.98295752646404 0.0483742427961589 MUS81 other 3.44396244573187e-06 1 0.000349096342374923 5.71450377031741 -1.98295752646404 0.000233920922779362 7.14843257407462 2.23196662998806 3.20275064959768 0.00152493888936001 -5.28345420153541 4.38252370742511 -1.20557344449361 0.229041386421742 TMEM217 other 1 1 1 3.20275064959768 -1.20557344449361 1.38029681905238e-11 18.7076144998973 5.88981665143577 3.17626432315798 0.00167776643501646 -32.8928373382626 9.77929893898555 -3.36351690887922 0.000889364675517341 ZNF596 other 1.63026857298276e-07 1 1 3.17626432315798 -3.36351690887922 0.518505696855287 10.9405298724463 10.1954100045225 1.07308385514592 0.284184590288321 27.3893623568867 47.2372598858461 0.579825384094592 0.562512340036866 COL6A5 other 1 1 1 1.07308385514592 0.579825384094592 9.89433030122125e-14 4431.51397490908 684.273538217089 6.47623169303846 4.35836969843313e-10 -4775.3781871513 1672.53413601558 -2.85517532008496 0.00463141678717554 CFL1 essential 1.26132922679968e-09 1 5.7024909134299e-06 6.47623169303846 -2.85517532008496 3.32656027930088e-08 132.916119803223 24.4007151430349 5.4472223057431 1.14851253816951e-07 -191.142589528233 113.25909493904 -1.68765775173387 0.0926274563796882 TMCC1 other 0.000328298233964204 1 0.00135409628250185 5.4472223057431 -1.68765775173387 3.35193820987768e-11 69.0667468544853 16.7563246797918 4.12183149791673 4.99529089812923e-05 -83.3486478957256 26.6181153747429 -3.13127532593132 0.00193029946828863 NAA16 other 3.89227064930997e-07 1 0.482145477487434 4.12183149791673 -3.13127532593132 0.0568563906844653 0.31591549813367 3.66619428109743 0.0861698736923197 0.931394775454448 -32.9690793307469 14.0083748583158 -2.35352634864532 0.0193081707592183 EFCAB12 other 1 1 1 0.0861698736923197 -2.35352634864532 1.15569858556161e-28 306.751893795925 48.4315289046026 6.33372310835253 9.81573324033999e-10 -466.364423149761 86.8658486225997 -5.36878912190156 1.69605067830675e-07 FAM192A other 1.80034725658788e-24 0.00267602876023239 1.26878167864635e-05 6.33372310835253 -5.36878912190156 1.584034265765e-07 97.4810933266258 21.3536278613176 4.56508345840447 7.59209772307489e-06 -217.64615259704 81.5189661990436 -2.66988362028067 0.00804775333120559 RAB43 other 0.00149627876744162 1 0.0786996849973943 4.56508345840447 -2.66988362028067 0.162458967381536 0.645196918237334 6.67823707506118 0.096611861930856 0.923105521184868 -27.5734269573083 15.0637707760495 -1.83044653076827 0.0682733125378351 FADS6 other 1 1 1 0.096611861930856 -1.83044653076827 0.0381391047436503 7.31976263234829 3.43421105965658 2.13142480330847 0.0339506540302728 -6.31501376838145 9.42295667456658 -0.67017327856619 0.503315906827926 HOXC5 other 1 1 1 2.13142480330847 -0.67017327856619 0.963282233880946 -1.75367815872044 7.4446130002043 -0.235563374304657 0.813948109395976 -3.22910927017168 16.7865314543263 -0.192363102464474 0.847600806769799 RAB37 other 1 1 1 -0.235563374304657 -0.192363102464474 2.85307169946779e-05 158.396297914164 39.4269725619481 4.01746032275977 7.61185303188355e-05 -12.1719558807467 65.0053225138375 -0.187245527135962 0.851607214348845 DCP2 other 0.224051720559205 1 0.723354393619894 4.01746032275977 -0.187245527135962 7.96952765849468e-16 511.274231268518 69.0604917575465 7.40328106934815 1.65324037048701e-12 -425.07419757613 168.800959650546 -2.51819775465805 0.0123679549875614 SNX32 other 1.07612531972654e-11 1 2.31784299942279e-08 7.40328106934815 -2.51819775465805 2.50008205566269e-13 2588.39089011198 334.6382067787 7.73489349894741 2.00573669720984e-13 -127.077975154099 747.402465556817 -0.170026165299609 0.865115489172381 RPL38 essential 3.14685328346262e-09 1 2.86639831398258e-09 7.73489349894741 -0.170026165299609 0.064640905361759 10.5858288291869 6.71186763672064 1.57718080900043 0.115946893657708 -22.2920674032271 21.410533931618 -1.04117288594598 0.298744273407684 CYP7B1 other 1 1 1 1.57718080900043 -1.04117288594598 0.644447558902159 54.7435538533191 58.4135294821255 0.937172506757541 0.349498155453243 45.5676374698998 142.777144822181 0.319152183121823 0.749855180198374 OVOL1 other 1 1 1 0.937172506757541 0.319152183121823 0.028120536336689 18.0392797334938 121.149842815476 0.148900562429697 0.881742028396248 -807.483533631241 326.120764179475 -2.47602612996104 0.0138920690559693 RARG og 1 1 1 0.148900562429697 -2.47602612996104 0.333140776565102 8.21839869286549 18.4926515119016 0.444414295460889 0.657099084626104 -30.2163600892332 32.205947886629 -0.938222970353193 0.348968348680641 CES4A other 1 1 1 0.444414295460889 -0.938222970353193 0.715872023315678 -12.8538511735039 20.1577521119822 -0.637662925017485 0.524233507065239 -27.3503944841355 35.1058101977572 -0.779084554097057 0.436612207701171 CES3 other 1 1 1 -0.637662925017485 -0.779084554097057 0.0590154487157751 102.228531764283 103.19853625426 0.99060059836908 0.322774165846147 -536.038413910109 301.599828383837 -1.77731670731559 0.0766502134245881 SSH3 other 1 1 1 0.99060059836908 -1.77731670731559 4.72075084342161e-08 177.269275258706 96.8463928234187 1.830416911675 0.068289870649723 -633.363428732336 168.663205396569 -3.75519620443085 0.000212152368884612 CES2 other 0.00046131177241916 1 1 1.830416911675 -3.75519620443085 1.93687910862808e-15 109.603550610147 18.935661272784 5.78820824006177 1.96967147728485e-08 -76.3608876441065 32.9774732280905 -2.31554695279266 0.0213326777260926 PDP2 other 2.59057580779005e-11 1 0.000241009001960574 5.78820824006177 -2.31554695279266 1.26001632375437e-10 452.150945266442 68.4980758463201 6.60092914552624 2.15554516034142e-10 -53.6018350360399 201.170493609004 -0.266449786320158 0.79009619798218 SP3 other 1.42633847848994e-06 1 2.85092402906756e-06 6.60092914552624 -0.266449786320158 0.494316428547868 9.21678654006761 7.99461575912425 1.1528742365821 0.249974152256027 2.33900386207776 21.5381306700829 0.108598276141332 0.913601196834961 KRT2 other 1 1 1 1.1528742365821 0.108598276141332 5.09837375449442e-10 54.965869297164 35.6423718119306 1.54214959619397 0.12419982157902 -298.808657325412 58.7060545459352 -5.08991209912779 6.69337549986711e-07 DMXL1 other 5.59852421981033e-06 0.0105032448343915 1 1.54214959619397 -5.08991209912779 4.43443504226342e-06 34.7337775701395 8.44554117425465 4.11267636418869 5.19592033452812e-05 -35.5917037547025 25.017861044829 -1.42265174832199 0.155991436593505 METAP1D other 0.0374355006267878 1 0.501042597858547 4.11267636418869 -1.42265174832199 2.92200654256831e-05 86.9484603566892 26.8215250945127 3.24174184914181 0.00133545848034988 -124.913935831497 70.0656789487642 -1.78281203730061 0.0757280030944416 ZNF621 other 0.229202193199058 1 1 3.24174184914181 -1.78281203730061 0.171228043016796 129.911575727292 69.2821561623607 1.87510872818172 0.0618530804130168 68.6441152453965 130.000945980184 0.528027813396528 0.597912123370753 EGFL7 other 1 1 1 1.87510872818172 0.528027813396528 1.05664313626669e-07 366.551307776128 75.0288306446212 4.88547275263187 1.8243965174463e-06 -312.298156030369 202.851175129523 -1.53954324312375 0.124911680028175 NADSYN1 other 0.00101089048846634 1 0.019858556092403 4.88547275263187 -1.53954324312375 5.07074216771033e-11 1193.54311395216 175.378775105697 6.80551630739144 7.20706809155737e-11 -109.80497937313 476.9949634177 -0.230201548851523 0.818120447301476 DHCR7 other 5.84859401623709e-07 1 9.67260608567914e-07 6.80551630739144 -0.230201548851523 0.500279172334961 70.2887299630079 65.5797598614956 1.07180523550952 0.284757575494564 101.763410380001 108.015509738036 0.942118503414948 0.346967966907525 LVRN other 1 1 1 1.07180523550952 0.942118503414948 0.156813688445474 46.9963986281034 30.1722006244424 1.55760593047468 0.120502387097269 -7.37910088704171 46.3437925286063 -0.159225227035247 0.873610910770542 NBEA other 1 1 1 1.55760593047468 -0.159225227035247 1.32003533657584e-16 309.741908871998 37.2388151301641 8.31771654896458 4.30769094907753e-15 -108.289813998196 91.0208944397515 -1.18972478423485 0.235188229180997 RNASEH2C essential 1.81597261252738e-12 1 6.30947493311386e-11 8.31771654896458 -1.18972478423485 0.536329376432595 -32.1005194123295 53.8316258812923 -0.596313391743295 0.551537420142145 -189.324883605778 175.428611872287 -1.07921325709177 0.281594413746075 MYEOV other 1 1 1 -0.596313391743295 -1.07921325709177 0.000639097925476774 134.883279502398 47.4256979849478 2.84409687644889 0.00479705897217429 -225.042579410245 135.66644121739 -1.65879326818663 0.0983272769965338 ANKRD13D other 1 1 1 2.84409687644889 -1.65879326818663 0.275591202692466 -9.46823490461183 8.25004601507676 -1.1476584357601 0.252211049109381 31.7994195965553 38.0779644518789 0.835113432514016 0.404454400561774 MRGPRF other 1 1 1 -1.1476584357601 0.835113432514016 1.48455435161727e-08 221.276171875 58.5131395180334 3.78164927907866 0.000191419424376136 -610.932348632808 182.743815923854 -3.3431081951762 0.000944317795859148 MYD88 other 0.000149524314294891 1 1 3.78164927907866 -3.3431081951762 6.29258772898554e-30 486.903515624999 38.9179630154906 12.5110226203565 1.079279571825e-28 42.613891601564 121.545641338255 0.350599915656142 0.726158894615473 OXSR1 other 9.85482164236426e-26 1 1.69857019013818e-24 12.5110226203565 0.350599915656142 4.72246770560562e-08 173.286427997127 29.6328950212945 5.84777247962449 1.42498542401476e-08 149.792728210101 113.44519741176 1.32039726341534 0.187812389921057 LCLAT1 other 0.000461432319514725 1 0.00017570070278102 5.84777247962449 1.32039726341534 0.000358820619717593 4.53526587998397 3.67518255808091 1.23402465273784 0.218262808107139 -11.8810279214436 5.41918564367484 -2.19240098100549 0.0292010175663469 ADH6 other 1 1 1 1.23402465273784 -2.19240098100549 0.121663687369102 74.7995698924733 40.9167063072299 1.82809362344145 0.0686388660398497 -59.8799999999997 132.435467979328 -0.452144738215797 0.651527748064516 MIR4435-2HG other 1 1 1 1.82809362344145 -0.452144738215797 2.47224852427834e-22 313.711944942673 33.8997017482933 9.25412109144785 6.53202554137744e-18 -236.66161445998 82.8592736794973 -2.85618741211028 0.00461711182402697 KAT5 essential 3.71208115920392e-18 1 9.85813294704684e-14 9.25412109144785 -2.85618741211028 0.430245566570063 7.91096596038449 23.405092783949 0.338001905542958 0.735623439041362 99.5731506558335 76.5487896104115 1.30078021040702 0.194438675695896 SH3RF3 other 1 1 1 0.338001905542958 1.30078021040702 0.853892341707421 -19.2196306947748 34.886779196432 -0.550914447749895 0.582144535824735 -24.4947099419924 74.5272693321234 -0.328667750227559 0.742659728843601 GXYLT2 other 1 1 1 -0.550914447749895 -0.328667750227559 0.359189108117496 8.17209431345359 8.53145892799952 0.9578777067816 0.338971937891447 -6.30384128324187 13.4134156417741 -0.469965402668167 0.638754925311362 HPSE2 other 1 1 1 0.9578777067816 -0.469965402668167 5.49736279271447e-06 116.468318719918 48.4540505943164 2.40368591049392 0.0168976562559578 -324.610866903176 101.800363216638 -3.18870047852758 0.00159559380306972 DCAKD other 0.0460074292122274 1 1 2.40368591049392 -3.18870047852758 3.47318517877306e-29 74.8020499121675 25.599060321741 2.92206233244581 0.00377033364132278 -300.111511156924 38.601222973937 -7.77466328876561 1.58209196558614e-13 TADA2B other 5.42407329368989e-25 2.52644265984451e-09 1 2.92206233244581 -7.77466328876561 0.000417923589738923 16.6537869659267 7.37074300850682 2.25944480043681 0.0246502077030147 -11.8288787909584 11.1144585300781 -1.06427845845543 0.288149937744325 CCDC96 other 1 1 1 2.25944480043681 -1.06427845845543 1.70570629664859e-09 502.567724878055 96.444500789704 5.21095262832972 3.75376280423277e-07 -626.645104699538 275.890134527481 -2.27135742194188 0.023918581855148 GRK2 other 1.81998861852405e-05 1 0.00428379411219043 5.21095262832972 -2.27135742194188 3.6894923090232e-14 400.036410076005 70.0584960353201 5.71003422446188 2.9440969000838e-08 -702.195837008116 171.240329477436 -4.10064521103741 5.44061040085071e-05 RELA other 4.76793091095068e-10 0.820172017928245 0.000357177835918167 5.71003422446188 -4.10064521103741 0.00032502167877113 35.5403339762625 16.2063639228413 2.19298629510423 0.0291583360911677 -29.9245078585371 25.0909056816448 -1.1926435911968 0.234052181446383 EVC2 other 1 1 1 2.19298629510423 -1.1926435911968 0.000462145568446751 72.2089716483056 18.4721398078797 3.90907455223477 0.000119257097442877 26.4662914054676 55.5505362764673 0.476436289899139 0.63417806168712 ZNF680 other 1 1 1 3.90907455223477 0.476436289899139 4.36010850720527e-18 256.909093726033 29.4027040252068 8.7376009194864 2.93870250431939e-16 -0.433156452783977 66.4326557362144 -0.00652023388172108 0.994802623758459 FAM222B other 6.18742998257499e-14 1 4.36749966191948e-12 8.7376009194864 -0.00652023388172108 0.00233256886539106 46.5213254088287 52.5503867415499 0.885270847532047 0.376825421484551 -508.122073637753 173.375663368954 -2.93075777628858 0.0036808670441388 BNC2 other 1 1 1 0.885270847532047 -2.93075777628858 0.843749635234203 4.6699465582355 8.17668048775012 0.571129881524877 0.568384923319025 2.14683255829046 15.2029395976029 0.141211674525692 0.887807634833677 DEC1 other 1 1 1 0.571129881524877 0.141211674525692 0.000932904419966276 126.065488565488 42.33029783735 2.97813847305971 0.00316357253186903 -3.11446061446125 64.0608528751029 -0.0486172205751523 0.96126028930739 HPSE other 1 1 1 2.97813847305971 -0.0486172205751523 1.41570592701922e-08 67.6464322080365 16.6846200776701 4.05441849398604 6.57367609314853e-05 -32.254836688337 25.3039511370235 -1.27469565972815 0.203508836157055 COQ2 essential 0.000142788099799159 1 0.628246224222205 4.05441849398604 -1.27469565972815 3.90205476164632e-05 914.460910009546 200.156341901795 4.56873312791767 7.4376423326267e-06 -106.636287149843 702.780083200911 -0.151734930597567 0.879508074669391 HSPA6 other 0.302097079646658 1 0.0771804144856672 4.56873312791767 -0.151734930597567 2.22388642261733e-11 873.736192086874 146.982670344248 5.94448440785909 8.44563110572023e-09 -697.196893497706 323.924751204793 -2.1523421439843 0.0322470159108813 TRMT112 essential 2.60172472582001e-07 1 0.000105224117946168 5.94448440785909 -2.1523421439843 0.316763776767136 -4.61152033967133 9.384257292017 -0.491410262546217 0.623538508519059 -40.7902926738965 26.8445855184395 -1.51949795037356 0.1298160409373 LRRN3 other 1 1 1 -0.491410262546217 -1.51949795037356 1.81974880080987e-15 869.58763590935 124.430630269473 6.9885335630474 2.1860609539833e-11 -1033.80896906968 351.439725605414 -2.94163947256893 0.00354911658858449 KDM2A essential 2.43536982012385e-11 1 2.97807083761145e-07 6.9885335630474 -2.94163947256893 3.10002044274957e-05 56.6885570054828 13.9608827626265 4.06052811769461 6.43231024267201e-05 -59.2180630314438 52.8367408235352 -1.12077433445831 0.263387233316537 ADCK5 other 0.242514599236299 1 0.615443444018858 4.06052811769461 -1.12077433445831 1.97450416016455e-11 218.434711327464 46.1578681154995 4.73233969083843 3.6411473303096e-06 -133.289050873964 70.1175649315734 -1.90093667690883 0.0584118410783809 MRPL57 other 2.315895929457e-07 1 0.0387199607105122 4.73233969083843 -1.90093667690883 3.89242949053537e-32 291.884062552071 22.4905478968234 12.978077007777 2.65772585693943e-30 64.4576622248698 38.1966258659464 1.68752241234836 0.0926492584676974 NOC3L essential 6.12357007451024e-28 1 4.19389140225042e-26 12.978077007777 1.68752241234836 4.52527826523264e-08 257.524876496506 68.9680891327043 3.73397146035165 0.000229412707162246 -493.697409764562 151.993912350739 -3.24813936380104 0.00130689223885361 ESRRA other 0.000442934236600971 1 1 3.73397146035165 -3.24813936380104 8.23711144354989e-06 298.769569248002 62.5569590480831 4.77596056129198 2.93726320509292e-06 20.607561389615 172.442740200077 0.119503792190411 0.904965105025206 RHOD other 0.0679232209635124 1 0.0314874615585961 4.77596056129198 0.119503792190411 0.00750498824023368 18.9682374964992 6.95652313650259 2.7266835924067 0.00682930475421936 -11.9454194366239 18.1245470294966 -0.659074095324059 0.510427019597598 ADAMTS20 other 1 1 1 2.7266835924067 -0.659074095324059 5.40151681128011e-06 240.727113405946 47.782783936789 5.03794659022798 8.79477433305119e-07 87.7078509437649 301.47507149255 0.290929032737396 0.771336648439279 COMMD1 other 0.0452485063280935 1 0.00978946331011928 5.03794659022798 0.290929032737396 2.64484451080126e-06 247.098015516413 57.4836906192812 4.29857604573377 2.4143441254838e-05 -189.772038351055 127.120110484063 -1.4928561470598 0.136659967151281 RAPH1 other 0.0227112798142504 1 0.240227240485639 4.29857604573377 -1.4928561470598 6.708605898083e-15 166.960717654621 19.5447950418129 8.54246449233341 9.90867776013944e-16 -25.3077819655572 65.4596390227378 -0.386616583033195 0.699345726653725 MTX1 other 8.84328429485300e-11 1 1.46291718450699e-11 8.54246449233341 -0.386616583033195 0.0805730124656045 56.9185446333321 26.916942819485 2.11459915842037 0.0353772018224921 -39.6350787896801 105.225099675687 -0.376669434496512 0.706714032654741 ADCY5 other 1 1 1 2.11459915842037 -0.376669434496512 0.00341937923197084 231.591295223319 100.377661517941 2.30719954740054 0.0217948948837053 -811.44898134311 392.096326209441 -2.06951436956252 0.0394420430802943 PARP14 other 1 1 1 2.30719954740054 -2.06951436956252 0.606028161344734 -4.10024637385173 9.07012159595423 -0.452060794386777 0.651586803644515 -34.22325887345 35.7600879282855 -0.957023901677268 0.33940815808804 PARP15 other 1 1 1 -0.452060794386777 -0.957023901677268 7.6769836451271e-14 347.384327209435 42.5160531774381 8.17066263793697 1.17988359737439e-14 -57.8680847042756 143.662007457156 -0.40280715638429 0.68740767107321 CKS1B other 9.8211651772111e-10 1 1.71767454105764e-10 8.17066263793697 -0.40280715638429 0.363517194842563 -3.58473310091911 3.02185105212187 -1.18627061330571 0.236632672692531 -9.51416368602947 8.4979961064526 -1.1195773176226 0.263959884442345 ABCD2 other 1 1 1 -1.18627061330571 -1.1195773176226 9.0197377499793e-07 484.178459049281 95.1418929794128 5.08901435410845 6.92333255700004e-07 1183.5618039477 601.994358727048 1.96606793201586 0.0503588067757312 AHSA2 other 0.0080591356796065 1 0.00775759413011854 5.08901435410845 1.96606793201586 0.00135045321665506 4.53521481668077 49.5028208192795 0.0916152805359827 0.927070898409026 -262.698122716393 82.0120127974679 -3.20316638691867 0.00152034680770778 ABLIM3 other 1 1 1 0.0916152805359827 -3.20316638691867 0.00166189083071913 3.44353802166652 12.6132004066996 0.273010648418576 0.785052958160508 -47.0632308580125 18.4640679232744 -2.54890910570623 0.0113577203957427 MAB21L3 other 1 1 1 0.273010648418576 -2.54890910570623 4.31980204101703e-14 45.4662978415294 6.91121770354382 6.57862330370753 2.439879536048e-10 -28.0055394067632 12.97352328425 -2.15866875891473 0.0317538597807564 MFSD4B other 5.57297661311608e-10 1 3.21990902372255e-06 6.57862330370753 -2.15866875891473 2.84044910577833e-09 107.039314205693 64.0660266810966 1.67076561089867 0.0959181566404331 -344.625069937663 93.4139242558871 -3.68922591233442 0.000271632544414043 VANGL1 other 2.99269717784804e-05 1 1 1.67076561089867 -3.68922591233442 9.22471259595551e-05 31.3651014994123 57.5297903497624 0.54519756301427 0.586062779897516 -353.473281700953 100.1827560885 -3.52828466197017 0.000490586057698703 GLRX other 0.686964347020807 1 1 0.54519756301427 -3.52828466197017 1.71216731958932e-19 265.06679506127 28.0935380260637 9.43515177103557 2.04196176420179e-18 -216.364326883736 109.880145023156 -1.96909393264943 0.0499801789550982 IQCB1 other 2.48452599745606e-15 1 3.0954098383535e-14 9.43515177103557 -1.96909393264943 1.29226784842303e-09 199.628592618688 30.0432260184008 6.64471227212484 1.65174411588626e-10 174.182736147293 88.4555368424962 1.96915583088307 0.0499501049168755 SYT12 other 1.38841257634571e-05 1 2.19401170913171e-06 6.64471227212484 1.96915583088307 3.30743973599073e-10 584.914840603158 95.5877114364051 6.11914263678449 3.36773689761357e-09 -778.503203823117 373.952561640772 -2.08182342810361 0.0383182865563772 GOLGB1 other 3.66728917926652e-06 1 4.26624910189686e-05 6.11914263678449 -2.08182342810361 0.299037007988111 -0.961873058452286 2.01257992039434 -0.47793036624544 0.633089358548032 -4.22785572493164 2.89415635620539 -1.46082491910523 0.145234868658829 LIPM other 1 1 1 -0.47793036624544 -1.46082491910523 7.51798587113243e-08 278.874819755704 48.9777060492744 5.6939134608538 3.31251172522777e-08 99.9259925230961 158.274374218351 0.631346628388754 0.528362231101802 DMRT2 other 0.000725635996281702 1 0.00040081391875256 5.6939134608538 0.631346628388754 1.19980575772384e-06 6.61175935090926 1.65530534152366 3.99428382489441 8.35776975683871e-05 -4.36159642797796 3.21295875561028 -1.35750153043888 0.175747120744097 ZNF483 other 0.0106206805673714 1 0.790310708206668 3.99428382489441 -1.35750153043888 0.00150334073499036 39.1159824707907 10.8698501452809 3.59857605652206 0.000380054489348912 4.20302992233051 50.1239708831103 0.0838526925995553 0.933235232644925 SLC2A14 other 1 1 1 3.59857605652206 0.0838526925995553 1.61514978349558e-06 98.9799279006632 44.7208723088217 2.21328258574997 0.0277052118174682 -378.660109484177 98.557179580207 -3.84203475684913 0.000151796292893882 GPR137 other 0.0141551727025552 1 1 2.21328258574997 -3.84203475684913 0.00459038874456541 75.8374128839123 154.902718241541 0.489580904356105 0.624832475178411 -499.587279769346 220.637048921981 -2.26429460605234 0.0243582801144642 SNCG other 1 1 1 0.489580904356105 -2.26429460605234 0.0326247097819884 -115.655254311268 95.6049120387832 -1.20972083802923 0.22745601350882 -351.907175433821 136.175697199779 -2.58421423697615 0.010291683197677 MMRN2 other 1 1 1 -1.20972083802923 -2.58421423697615 1.45866164801242e-25 313.029855072053 52.5962206693464 5.95156555144826 8.22212270814378e-09 -440.620186328525 92.8692355766557 -4.7445225923587 3.39109992635169e-06 TNKS other 2.2421088191599e-21 0.0526502174565363 0.000102472315311596 5.95156555144826 -4.7445225923587 0.00472104549174114 55.243054943476 31.1213321765009 1.77508644649823 0.0770101663245819 -67.1824394652738 45.4766761020377 -1.47729441163497 0.140762193361147 ZBTB21 other 1 1 1 1.77508644649823 -1.47729441163497 2.59180529750547e-05 144.722100948773 96.3148466333453 1.50259389914938 0.134112460731145 -453.533764233053 170.687377940743 -2.65710194687333 0.00835108435269853 PPP1R3B other 0.204441601867231 1 1 1.50259389914938 -2.65710194687333 2.98863481190407e-07 18.7453258149995 6.97334682315518 2.68813903716293 0.00763171370814718 -26.8249834083505 11.6726135299031 -2.29811287246252 0.0223199128754174 FAM86B3P other 0.00277644174025888 1 1 2.68813903716293 -2.29811287246252 5.63812171939679e-07 102.456224350205 38.9798243198546 2.62844243497574 0.00907076066822124 -122.876494729219 58.2723310793016 -2.10865933202499 0.0358985566911929 STOX2 other 0.00512448883075974 1 1 2.62844243497574 -2.10865933202499 1.19821160234482e-06 226.648595497141 74.5193359677133 3.04147363303587 0.00258672060530624 -589.307590783322 178.897170932664 -3.29411352740248 0.001119712367055 MAP3K11 other 0.0106077673155587 1 1 3.04147363303587 -3.29411352740248 0.203430285873498 138.578560025754 95.1102721850239 1.45703042207858 0.146283022390024 -327.514494243486 417.056218645213 -0.785300589228477 0.432973626626679 TRIB1 other 1 1 1 1.45703042207858 -0.785300589228477 0.741253918920028 5.7086301062544 7.62663390538473 0.748512407580475 0.454805091233131 0.653788175963306 18.3091168445677 0.0357083403592612 0.971541403383858 KCNK7 other 1 1 1 0.748512407580475 0.0357083403592612 0.000134663606276357 64.6271721577977 20.4919203771724 3.15378797927553 0.00179298804092767 -94.8124190300068 55.4522515121444 -1.70980287444672 0.0884469550658204 SFT2D3 other 0.982236344179747 1 1 3.15378797927553 -1.70980287444672 0.655814672039873 -632.697112780143 692.855939459964 -0.913172676665353 0.36196042965844 -637.888356819444 1026.14229911836 -0.621637327851609 0.534701031205211 C1QB other 1 1 1 -0.913172676665353 -0.621637327851609 0.785352515504689 -381.249871657253 572.461823996037 -0.665983050181339 0.505986346857554 -471.263273751184 849.650948268967 -0.554655149519118 0.579586342685087 C1QA other 1 1 1 -0.665983050181339 -0.554655149519118 0.268318010830233 -40.5228188224596 180.548659728179 -0.224442645453408 0.822583274514367 -380.192925664924 265.214187893708 -1.43353162470063 0.15286724787654 NDNF other 1 1 1 -0.224442645453408 -1.43353162470063 0.589247216433493 -40.8802195509982 85.6901104067441 -0.477070450218264 0.633696444224878 314.030620758843 388.663860583426 0.807974840489284 0.419813722370878 OLR1 other 1 1 1 -0.477070450218264 0.807974840489284 0.000914979267365459 748.770852360824 208.557632204233 3.59023472048043 0.000391615057535457 6.09880135653955 496.992083795034 0.0122714255526347 0.990218027578878 DAG1 other 1 1 1 3.59023472048043 0.0122714255526347 0.39628154299619 54.3254788758691 57.9229762485771 0.937891703677842 0.349135176967898 -130.673365108448 190.70916872972 -0.685197077722273 0.493805227120707 INSM1 other 1 1 1 0.937891703677842 -0.685197077722273 0.00169134549582947 36.0116635903475 13.9970342050149 2.57280671482857 0.0106203861864947 -16.1283580005058 23.267173549959 -0.693180801091941 0.488789736497523 DAB1 other 1 1 1 2.57280671482857 -0.693180801091941 6.06482169041e-07 97.2993989374318 18.2698714808173 5.32567506233378 2.10927673774013e-07 -37.0193752972099 51.5231880804047 -0.718499314123171 0.473066202206482 ARV1 other 0.00549654789801858 1 0.002446339160431 5.32567506233378 -0.718499314123171 1.62825809018147e-05 294.987017268614 90.8130094446233 3.24829029532926 0.00130733422135646 -746.399098995144 297.862945555509 -2.50584743799913 0.0128024345769942 NAA20 essential 0.130960798193295 1 1 3.24829029532926 -2.50584743799913 0.711866900224797 -98.1710106655125 119.42440648976 -0.822034737714442 0.411777120821804 -116.627037874015 227.923176489391 -0.511694508958565 0.60927999097536 SAA1 other 1 1 1 -0.822034737714442 -0.511694508958565 3.98054257627594e-16 149.641797161397 50.6152927908088 2.95645424357933 0.0033840166023433 -377.462851246674 74.2246715391088 -5.0854095197685 6.82529070334757e-07 MINOS1 other 5.41672233779629e-12 0.0107095636426227 1 2.95645424357933 -5.0854095197685 0.135147037837768 -83.9210799407528 102.262268715944 -0.820645590935034 0.412574797629022 -489.677737078323 245.499108773118 -1.99462124129692 0.047093226066264 EHBP1L1 other 1 1 1 -0.820645590935034 -1.99462124129692 0.381517489230656 -8.06974565460055 10.4393856847737 -0.773009628944986 0.440205621162114 -39.544141683942 29.842057516383 -1.32511445171743 0.186274588083726 THAP2 other 1 1 1 -0.773009628944986 -1.32511445171743 1.13859360212932e-17 479.783090514234 68.6008285927533 6.99383812639425 2.08844417883047e-11 -257.744332077697 123.999235840301 -2.07859613271848 0.0385953230510908 RNF26 other 1.60313979179809e-13 1 2.84717594899958e-07 6.99383812639425 -2.07859613271848 7.0237255846669e-05 348.662706395478 109.104328772156 3.19568169585273 0.00155885948373434 -458.588112510569 240.447343010664 -1.90722886253823 0.0575403983043107 PPP1R14B other 0.529448434572191 1 1 3.19568169585273 -1.90722886253823 6.30029090807837e-09 253.198332950288 57.0346900102763 4.43937422829278 1.31968388860552e-05 -411.634350096475 135.974322460924 -3.02729473217099 0.00270785572504487 SSSCA1 other 6.49938010077364e-05 1 0.134225048310068 4.43937422829278 -3.02729473217099 0.367883849173147 -58.4539708003473 49.5417936464125 -1.17989209711587 0.239077820369484 -141.13305527937 132.844242469084 -1.06239497215858 0.289002219987178 AGR3 other 1 1 1 -1.17989209711587 -1.06239497215858 1.60918337519977e-06 1078.34092012624 211.734836658714 5.09288380288771 6.5982849352868e-07 66.0378125758602 547.705974629459 0.12057164908697 0.904119341134292 SMARCC1 other 0.014104492283626 1 0.00740591501136591 5.09288380288771 0.12057164908697 1.5805279352655e-07 34.4569926324132 8.7052139415925 3.95820170114163 9.66213770059088e-05 -49.5064206337596 21.1225622936454 -2.34376965945336 0.0198154853884117 ZNF417 other 0.00149344084603237 1 0.907951079724525 3.95820170114163 -2.34376965945336 0.121630418234306 -8.88748190968548 80.349766301437 -0.110609928550925 0.912008460281633 -340.858495081225 176.500707683469 -1.93120186063226 0.0545125940976459 PTPRM other 1 1 1 -0.110609928550925 -1.93120186063226 7.05609517366407e-06 116.613612087766 59.3701255654526 1.96417998070772 0.050523642246547 -484.207107570429 130.841636689173 -3.70071117897057 0.000260016754544255 FKBP2 other 0.0584809167993278 1 1 1.96417998070772 -3.70071117897057 2.74584314462773e-06 206.720993368641 65.7591115595945 3.14360988866614 0.00185282458192301 -418.905158217988 144.92187277249 -2.89055854857479 0.004154557086556 VEGFB other 0.0235620800240505 1 1 3.14360988866614 -2.89055854857479 0.353881667492472 98.098599185664 88.271816512 1.11132412430108 0.267413837212102 -75.999243425599 172.374342880927 -0.440896493964289 0.659639448570732 PEAK1 other 1 1 1 1.11132412430108 -0.440896493964289 0.0812651215782435 -30.2113501409926 42.1477000262296 -0.716797123501193 0.474112066316334 -149.127149913235 70.2755358613085 -2.12203504513353 0.0347353648807523 TNFRSF10D other 1 1 1 -0.716797123501193 -2.12203504513353 0.117294667100281 30.2481255708247 19.1690579546922 1.57796620169436 0.11573136830793 -35.2137026259705 45.6797958271838 -0.770881348927024 0.441443911198836 MST1 other 1 1 1 1.57796620169436 -0.770881348927024 2.69547698398117e-06 109.929526123937 35.98806052179 3.05461101626681 0.00247717416880667 -254.413365735116 85.5795155660797 -2.9728301691387 0.00321500522797832 GMPPB essential 0.0231379744304944 1 1 3.05461101626681 -2.9728301691387 8.90499002072818e-22 146.256219756587 24.2719393840017 6.02573273782105 5.47614808178793e-09 -253.47190548344 52.6341243862914 -4.8157332992407 2.44213711199407e-06 MOB1B other 1.32960405999492e-17 0.0380216326966356 6.87585153149293e-05 6.02573273782105 -4.8157332992407 2.07157931605875e-25 172.943106510156 14.8194669016787 11.6699951258412 1.23363981222189e-25 -101.743804491088 104.252625556376 -0.975935176194375 0.329993391651818 ZNF622 other 3.18111719773982e-21 1 1.93027621418358e-21 11.6699951258412 -0.975935176194375 0.844177903435299 209.891457234182 386.244434091763 0.54341613420976 0.587296723464653 16.1693579614822 750.676816596331 0.0215397060412711 0.982831218066622 CSPG4 other 1 1 1 0.54341613420976 0.0215397060412711 0.00226021874458937 121.80514472922 59.3886383400279 2.05098396147472 0.0412444206989257 -214.152184830604 115.654577488228 -1.85165334119526 0.0651795901847404 SNX33 other 1 1 1 2.05098396147472 -1.85165334119526 3.01988449323983e-08 15.2770756680263 2.69125525150983 5.67656139619444 3.5081462584978e-08 23.9688495796221 10.0432798520535 2.38655597899339 0.0176883828921321 C2orf70 other 0.000298998763675676 1 0.000424099801189799 5.67656139619444 2.38655597899339 0.0468497204165885 91.7640419070108 55.444015970555 1.65507567048795 0.0990753369326811 -178.008060525575 139.150798256277 -1.27924570147081 0.201912900845732 NABP1 other 1 1 1 1.65507567048795 -1.27924570147081 1.40183394955419e-08 13.7291717306251 2.21766598137184 6.19082036968087 2.18759939101579e-09 6.84139349038542 8.27592999839051 0.826661594735084 0.409150814234381 ADGRF3 other 0.000141459063849514 1 2.79093930305794e-05 6.19082036968087 0.826661594735084 0.182136980804736 -12.3303319846832 6.76931724544876 -1.82150304640741 0.06962474132005 -5.36951809840316 17.5944381456421 -0.30518269773412 0.760459557543705 XCR1 other 1 1 1 -1.82150304640741 -0.30518269773412 6.1505519512198e-08 42.9723431817094 14.3366166151749 2.99738385528315 0.00297659288041486 -111.368181842308 32.0541048831036 -3.47438127654635 0.000596299927879156 CCDC106 other 0.000596665044787833 1 1 2.99738385528315 -3.47438127654635 3.76359141564029e-09 50.5285289212962 10.7212593514097 4.7129285156834 3.90848588887834e-06 -72.4344693130171 24.8312887378554 -2.91706443744059 0.00382937917194325 CEP83 other 3.93069487449471e-05 1 0.0414924861963325 4.7129285156834 -2.91706443744059 0.168105957103401 -8.67037943230138 26.0388701846089 -0.332978327048394 0.739407148962984 -94.6820182911471 53.4556201975467 -1.77122663512736 0.0776427933850787 SULT1B1 other 1 1 1 -0.332978327048394 -1.77122663512736 0.40687886811738 69.4968310623504 87.6144576718079 0.793211907133823 0.428348290925616 252.695793847646 200.783295648703 1.25854988599137 0.209276103019459 NUDT4 essential 1 1 1 0.793211907133823 1.25854988599137 0.00241353244080263 365.6868777487 111.736666059403 3.27275629965804 0.00120217883358877 -92.062258856541 305.80386936957 -0.301050013024138 0.763605517935877 PC other 1 1 1 3.27275629965804 -0.301050013024138 0.924180494326974 20.9134033716534 81.4051334784433 0.256905215654384 0.797448331432884 66.6084447086046 170.134937554739 0.391503624510834 0.695734954394784 UGT2A1 other 1 1 1 0.256905215654384 0.391503624510834 0.000659840560611887 50.0210765714543 16.4159995574468 3.04709295321364 0.00253699734090042 -28.2008396289083 31.7009402400879 -0.88959000633194 0.37446929415531 SCAI other 1 1 1 3.04709295321364 -0.88959000633194 3.16760999252258e-21 65.1772926004177 11.7129105928485 5.56456843785802 6.2715826764328e-08 -87.0686920885377 18.667539803151 -4.66417605140666 4.8562405832991e-06 NMNAT1 other 4.70358407789678e-17 0.0751988854323865 0.000749140550699898 5.56456843785802 -4.66417605140666 1.19853920581345e-07 210.896034567269 38.6459317731364 5.45713416370173 1.08617511939365e-07 -41.9135829533495 105.767210427905 -0.396281444729217 0.692206971859203 LRFN4 other 0.00114220786314022 1 0.00128190387590839 5.45713416370173 -0.396281444729217 0.000182426541123901 -43.7251934921238 141.205377491748 -0.309656716116773 0.757059989552066 -789.255991637404 211.401130301777 -3.73345208945067 0.000230186086285179 SLC19A1 other 1 1 1 -0.309656716116773 -3.73345208945067 0.33308581224978 3.52402499262754 15.0726743083683 0.233802238443579 0.81531373911995 -25.8911972869361 23.4116204458066 -1.10591222623266 0.269738121962541 HSPB7 other 1 1 1 0.233802238443579 -1.10591222623266 1.29972132201527e-14 157.360014817114 20.8533088504894 7.54604537559615 6.71454544087893e-13 -92.2085671694139 57.0718884009667 -1.61565649486818 0.107323631367768 RCE1 other 1.69899571213836e-10 1 9.49235288977054e-09 7.54604537559615 -1.61565649486818 2.82744906157605e-08 303.243225238921 124.14507888417 2.44265200009945 0.0152164691960122 -765.271752849255 218.149788459655 -3.5080105199863 0.000528065924093187 UQCRH essential 0.000280596044870807 1 1 2.44265200009945 -3.5080105199863 0.0388039010603258 3.37935371226869 1.91582271843921 1.76391775697377 0.0788894067551753 -10.3075486730395 7.70892375145341 -1.33709308917424 0.182330291782664 SPDYE2B other 1 1 1 1.76391775697377 -1.33709308917424 3.10428743954311e-10 430.486165830084 111.823252196661 3.84970171564138 0.000147360763520502 -484.245797797244 173.509226687176 -2.79089364319686 0.00562704552762758 PSMD1 essential 3.44731120161263e-06 1 1 3.84970171564138 -2.79089364319686 0.0235909102761142 -49.4697759758054 70.3227410391762 -0.703467686907229 0.482370511280837 660.824758113736 266.311333404911 2.48139930683683 0.0136957788267108 MUC13 other 1 1 1 -0.703467686907229 2.48139930683683 0.00191366561195829 47.6421075968076 15.9910499662986 2.97929827604904 0.00315300619678933 -57.6847037957954 52.5238833808367 -1.09825664217436 0.273074477166383 SUSD5 other 1 1 1 2.97929827604904 -1.09825664217436 0.161105013034822 159.061509536157 138.703595900596 1.14677278915069 0.252490764574388 -676.913617286496 525.268768345727 -1.28869953456086 0.198605676355678 HEG1 other 1 1 1 1.14677278915069 -1.28869953456086 0.0408591375988918 25.4066862722969 21.3327594236427 1.19097045852114 0.234699648186157 -104.095882817635 57.6173768661906 -1.80667514696799 0.0719139632762529 C11orf80 other 1 1 1 1.19097045852114 -1.80667514696799 7.7615866916652e-14 1532.02944042648 191.418630919117 8.00355447675226 3.48541414830125e-14 -413.219015818118 517.399435946292 -0.798646050052926 0.425189907065729 TOMM20 essential 9.92784553730896e-10 1 5.03502927863598e-10 8.00355447675226 -0.798646050052926 2.13190653195562e-05 335.603223041317 136.420469438564 2.46006500653815 0.01451105269771 -429.607114692267 205.62826834577 -2.08924151406007 0.0376118606090497 AGFG1 other 0.169635802747709 1 1 2.46006500653815 -2.08924151406007 2.33236606700784e-06 156.527953132472 54.4800288714796 2.87312537043119 0.00438844282239086 -266.682861242059 100.898208853272 -2.64308816056263 0.00869724743510519 STAT5B other 0.0201353162564787 1 1 2.87312537043119 -2.64308816056263 0.231823992358685 -28.4938588491899 18.4542896744457 -1.54402360382618 0.123789579881997 -50.6472967954678 40.1948990255429 -1.26004289159385 0.208775056222372 CD7 other 1 1 1 -1.54402360382618 -1.26004289159385 3.49330148530433e-09 355.848515943008 92.4979964810027 3.84709430994099 0.000149088335573715 -511.75661478638 172.136226411535 -2.97297451823359 0.00321453888174556 CNP other 3.65399335362833e-05 1 1 3.84709430994099 -2.97297451823359 0.00263237230387998 2193.55942711121 1455.19318076627 1.50740084279128 0.132872763361262 -5823.65601354825 2726.65298200091 -2.13582588323163 0.0335899214834655 JUP other 1 1 1 1.50740084279128 -2.13582588323163 0.000195609492098549 168.344057988189 70.7348428442155 2.37993117987052 0.0180053653602597 -276.075433740481 134.64380089489 -2.05041325263833 0.041282473344652 HAP1 other 1 1 1 2.37993117987052 -2.05041325263833 1.42757004245227e-06 228.919338559794 43.9973850467822 5.20302145948867 3.9022371615358e-07 339.815142502538 161.317948310462 2.10649308438111 0.0360912672186139 TDRD12 other 0.0125583336634527 1 0.00444816014043465 5.20302145948867 2.10649308438111 3.56325977345725e-14 2740.47266326443 428.810018758353 6.39087834561246 7.13326548762031e-10 -1659.96668632847 816.850203906205 -2.03215556339516 0.0431095068775043 EIF1 essential 4.60586958317085e-10 1 9.2639718887725e-06 6.39087834561246 -2.03215556339516 1.93830177544387e-10 101.832724285431 15.0300514658705 6.77527449035473 7.7602404777895e-11 14.5988593335406 34.0362752792947 0.428920591743525 0.668323033539208 ENDOV other 2.17516225240312e-06 1 1.04064824807157e-06 6.77527449035473 0.428920591743525 0.00666761473508166 659.95596796125 247.177380024948 2.66996910435187 0.00804575848073577 -494.777233647771 559.745079279855 -0.883933154507283 0.377518709001099 RNF213 other 1 1 1 2.66996910435187 -0.883933154507283 0.00125371770830476 9.53068304550367 3.036457057359 3.13875113840507 0.00188413140653152 -6.60373869500233 7.1159236413281 -0.928022703426568 0.354221594155601 TIGD3 other 1 1 1 3.13875113840507 -0.928022703426568 0.624901112717285 1.21730368371441 28.9897723166876 0.041990798355242 0.966536953932247 -60.1467673439028 64.4234426912166 -0.93361616255418 0.351333009924759 KCNH6 other 1 1 1 0.041990798355242 -0.93361616255418 0.902474119375481 -0.887555886500242 4.29060067469007 -0.206860519958398 0.836274131137915 3.17966783185941 9.35779589771033 0.339788115344277 0.734279295062462 MARCH10 other 1 1 1 -0.206860519958398 0.339788115344277 0.0468818857642073 69.080294721522 42.3475120182177 1.6312716244535 0.103994548546472 -56.809002780882 73.8265214961551 -0.76949315272616 0.44227078044054 PLK3 other 1 1 1 1.6312716244535 -0.76949315272616 1.01113988727256e-12 713.977834021366 233.044841622244 3.06369293158908 0.00240816878949025 -1629.14226197374 401.103967564514 -4.06164584176471 6.39711826856034e-05 NET1 other 1.24592656909725e-08 0.961486875764619 1 3.06369293158908 -4.06164584176471 8.96576246167839e-08 267.793260005984 57.2429221085649 4.67818989914765 4.5662138854103e-06 -274.445772771972 151.27370892697 -1.81423311901783 0.0707435243442943 DPY19L1 other 0.000860713196321126 1 0.0481781227049641 4.67818989914765 -1.81423311901783 0.422252462982042 5.19794383187689 4.4205276969108 1.1758650071369 0.240680773960711 9.09156296228517 9.7714611886522 0.930420004414836 0.352981733213987 PHOSPHO1 other 1 1 1 1.1758650071369 0.930420004414836 6.04885668399434e-27 112.273025878883 16.1412885497065 6.95564208106079 2.70134734994247e-11 -208.13288503066 36.007351430539 -5.78028865666959 2.07571740021293e-08 ZNF791 other 9.36121060414964e-23 0.000329374837065788 3.6716713180418e-07 6.95564208106079 -5.78028865666959 2.38768126902023e-25 305.778750420365 25.6720615086916 11.9109542611854 2.06205035559551e-26 -3.66231695013692 250.504470309289 -0.0146197668473348 0.988346698352542 PHC3 other 3.66437444356535e-21 1 3.23226393239597e-22 11.9109542611854 -0.0146197668473348 0.000111551511814201 78.9115908650857 18.5851077395124 4.24595821402304 3.02887559689213e-05 187.602850442898 181.350943256013 1.03447408143921 0.301872124332598 GPR160 other 0.822357745094288 1 0.298828866389377 4.24595821402304 1.03447408143921 0.000259156009492918 284.916019747896 77.7882619083862 3.66271224935518 0.000299876837690066 -131.998002260528 174.839955202742 -0.754964745372216 0.450923327253263 CBX2 other 1 1 1 3.66271224935518 -0.754964745372216 0.00281803854387184 100.728453168876 97.4071855004139 1.03409674195388 0.302006104328046 -753.774834536006 263.08582049785 -2.86512907882911 0.00449246684552852 SPTBN2 other 1 1 1 1.03409674195388 -2.86512907882911 2.16273857027048e-18 592.344004922618 61.1309507196353 9.68975613743166 3.89363560389676e-19 -554.246385322078 557.266857924943 -0.99457984525742 0.320872526790752 GOLIM4 other 3.08557911820489e-14 1 5.93156447897632e-15 9.68975613743166 -0.99457984525742 2.15866062624824e-11 117.558070062468 19.9306191276307 5.8983651892425 1.08283786607562e-08 -132.805286881709 53.8303540882063 -2.46710780806114 0.0142349750903417 RBM4B other 2.52649639696094e-07 1 0.000134261067014716 5.8983651892425 -2.46710780806114 0.186824540812972 -18.4011406507795 23.4031135411629 -0.786268913254399 0.432394412838684 -93.7087047740573 51.2545488804133 -1.82830025472856 0.068599651005871 HOXB2 other 1 1 1 -0.786268913254399 -1.82830025472856 0.234159886600682 -206.651952183421 122.349610622907 -1.68902827831909 0.0923557573305503 -200.48718092044 274.607390722155 -0.73008661709069 0.465963255517117 C1QTNF1 other 1 1 1 -1.68902827831909 -0.73008661709069 0.157240794125476 23.3404922264176 15.0291410526402 1.55301571424918 0.121577860253211 -5.62498652798228 24.0370371719031 -0.234013305706301 0.815150042328918 MARCH3 other 1 1 1 1.55301571424918 -0.234013305706301 3.30418633239236e-13 23.9070245333024 4.01852835534939 5.94919891543824 8.26437891276261e-09 -14.2190645976724 7.85357030384507 -1.81052235449026 0.0713181754879478 SWSAP1 other 4.14080631175411e-09 1 0.000102990690010848 5.94919891543824 -1.81052235449026 0.949665083058227 10.332356215421 45.924916939208 0.22498366690784 0.822160292195658 -7.02662553074814 75.1111096860531 -0.0935497499653219 0.925535446957212 SLCO4C1 other 1 1 1 0.22498366690784 -0.0935497499653219 8.01639393139567e-10 369.992325922581 78.8980413015537 4.68949950871968 4.33191647711042e-06 -694.861556257761 213.094709849761 -3.26081091711598 0.00125197755314552 RBM4 other 8.71301856403395e-06 1 0.045823012494874 4.68949950871968 -3.26081091711598 0.35634399521558 53.3309782458267 40.1648834124082 1.32780114654462 0.185352946869585 23.849914617548 59.0222128594565 0.404083707846389 0.686467530918077 PIFO other 1 1 1 1.32780114654462 0.404083707846389 1.79715207499141e-15 264.807522193293 30.177729846927 8.77493183007795 1.98185605277556e-16 117.465859912424 232.384987842538 0.505479553576056 0.61363444355827 XXYLT1 other 2.40548805237601e-11 1 2.95217277621448e-12 8.77493183007795 0.505479553576056 3.21287241626657e-09 159.369124946675 24.8712385033604 6.40776794951897 6.47955027802881e-10 -15.3034885066785 84.8752662816267 -0.180305631747883 0.857046895706388 UBXN2A other 3.3686967284555e-05 1 8.42859900165988e-06 6.40776794951897 -0.180305631747883 0.0052105473663285 4.38549727806025 2.0710820330429 2.11749086134311 0.0351532398973816 -5.17045160418098 4.01286481599665 -1.28846892214504 0.198710819112679 TCAP other 1 1 1 2.11749086134311 -1.28846892214504 9.30377263297577e-08 115.591620916508 27.4550258988506 4.21021715085494 3.4669360445355e-05 -199.259607533342 74.1529280235507 -2.68714416064674 0.00764889766373123 CCS other 0.000892603946407695 1 0.340002417887596 4.21021715085494 -2.68714416064674 0.0106677915088388 12.7136995134533 5.1128778239035 2.4866034259639 0.0135154612197625 -57.2801425553581 39.3857969693915 -1.45433498780977 0.14704130327489 NRROS other 1 1 1 2.4866034259639 -1.45433498780977 2.45141602457649e-06 30.7005393047658 6.10523776201028 5.02855752740693 9.13545698837901e-07 -36.8273058861077 47.030197713744 -0.783056582289157 0.434295762556447 CEP19 other 0.0211140462196773 1 0.0101595417167763 5.02855752740693 -0.783056582289157 2.23293879282437e-18 255.583331495297 26.5658610725005 9.62074335922286 5.38722687919236e-19 -89.4299314960463 201.581075060125 -0.44364249704181 0.657661720562805 FBXO45 other 3.18461730632612e-14 1 8.19774314206702e-15 9.62074335922286 -0.44364249704181 0.0137408194228467 4.78652580251932 3.30595914766823 1.44784783741062 0.148811249932012 -7.91686566436409 5.21769314906131 -1.51731147045095 0.130349422288039 SPERT other 1 1 1 1.44784783741062 -1.51731147045095 4.08509093226722e-19 209.706364041161 59.4305657386669 3.52859444352759 0.000490037417125196 -624.523592360802 102.016258245123 -6.12180453492231 3.20660464661004e-09 GNG5 other 5.89764577891418e-15 5.10138733229191e-05 1 3.52859444352759 -6.12180453492231 3.81422875286346e-05 55.265680617635 17.4141521966147 3.17360730477472 0.00167841969591462 -36.1956596505488 27.4842182115511 -1.31696158762618 0.188959937275666 SLC25A30 other 0.295602728346918 1 1 3.17360730477472 -1.31696158762618 0.834300325134371 30.0929745233919 87.8660244908674 0.342487038622303 0.732249876807048 128.525534117377 243.285287181417 0.528291437622103 0.597729414891744 CD34 other 1 1 1 0.342487038622303 0.528291437622103 0.336849876551705 16.2797652635143 77.9094575651048 0.208957497232094 0.834637247424783 -281.999294662003 210.424656689941 -1.34014377924126 0.181312906647785 CTSF other 1 1 1 0.208957497232094 -1.34014377924126 0.811502704959175 10.5519917784787 56.1264853816069 0.188003786567698 0.851014899495378 108.064755258827 167.135419308534 0.646570043057946 0.518459484291387 MSRB3 other 1 1 1 0.188003786567698 0.646570043057946 3.02872439893542e-18 256.081665432959 29.7397134579522 8.61076438396161 6.13081239503685e-16 -152.979356364133 88.5599631816497 -1.72740989119824 0.0852376300846373 LEMD3 other 4.31138918188458e-14 1 9.07360234465454e-12 8.61076438396161 -1.72740989119824 1.07911612193953e-17 87.0147578614996 13.3936334136323 6.49672536004564 3.89425290629309e-10 -52.1590478016854 24.4906946037713 -2.12974963126009 0.0340901053948604 C16orf91 other 1.52015088097622e-13 1 5.1061444107315e-06 6.49672536004564 -2.12974963126009 0.0430318862448761 132.651617090517 66.7939957587565 1.9859811586901 0.0480428536077326 1.47820518289655 106.924183245603 0.0138247975156485 0.988979930945648 TLR10 other 1 1 1 1.9859811586901 0.0138247975156485 0.00361975292031236 -17.492787538622 29.7889467678733 -0.587224102783235 0.557542121110405 -142.105750264589 47.6863042361712 -2.98001181976268 0.00314391915196894 TLR1 other 1 1 1 -0.587224102783235 -2.98001181976268 0.00238380846981439 -21.6899510027974 19.7925155105183 -1.09586631326729 0.274110195752059 -104.486876692405 31.6839639745711 -3.29778422852215 0.0011047392094712 TLR6 other 1 1 1 -1.09586631326729 -3.29778422852215 1.88302686970659e-06 49.990909446903 24.7261692084485 2.02178141811882 0.044174337320737 -133.162785233586 40.4401386286691 -3.29283701167094 0.0011225909338917 FAM174A other 0.0164181112769717 1 1 2.02178141811882 -3.29283701167094 0.00714085180323563 20.971034727428 48.9990310823758 0.427988763536407 0.668996736337734 -202.132827118178 79.4461362703218 -2.54427511025086 0.0115017681961434 RGMB other 1 1 1 0.427988763536407 -2.54427511025086 1.37812580830848e-35 29.5193119828469 2.14161896879016 13.7836433151892 3.85885807958035e-33 5.53486857822028 5.80560855375502 0.953365788783739 0.341251221040651 FAM53A other 2.17867909035487e-31 1 6.10664291093591e-29 13.7836433151892 0.953365788783739 0.000298155542245309 33.2878644353226 24.1414351376873 1.37886849913727 0.169064003155462 -76.8372802862858 35.9442128789166 -2.13768153847529 0.0334308580374761 CYB561D1 other 1 1 1 1.37886849913727 -2.13768153847529 0.64579835259693 -2.96728764931326 4.57006530556516 -0.649287800264008 0.516714713986325 -9.27476654006133 10.917797196224 -0.849508959854017 0.396364944224759 GSTA3 other 1 1 1 -0.649287800264008 -0.849508959854017 0.0041803426417217 39.1573848101324 18.8263863673662 2.07992038652772 0.038469203652004 -96.9890299601552 50.7991571842943 -1.90926454957291 0.0572800867777484 ZDHHC24 other 1 1 1 2.07992038652772 -1.90926454957291 8.19241972848841e-17 228.087952951296 26.5422462973569 8.59339297797146 7.40946230565902e-16 -96.8793646057085 98.2475816345398 -0.986073784147474 0.324996359437686 TRMT10C other 1.13342126943637e-12 1 1.09519262339946e-11 8.59339297797146 -0.986073784147474 0.602673769114269 -21.3189064642643 24.6753300945773 -0.863976545908471 0.388362015369485 39.6261076114078 85.6115425651902 0.462859404515856 0.643835233867712 SELP other 1 1 1 -0.863976545908471 0.462859404515856 3.1049515036908e-18 141.688040281114 21.254528203175 6.66625195942712 1.48168258990448e-10 -62.8036623107382 34.9593330349206 -1.79647770305012 0.073540451534133 CTU2 essential 4.41865648490237e-14 1 1.97078601283195e-06 6.66625195942712 -1.79647770305012 0.000162726108378821 161.4017963072 53.0056975209461 3.044989573874 0.00255506943412287 -89.3550097109561 92.9919642078108 -0.960889583010343 0.337461085943897 MGA other 1 1 1 3.044989573874 -0.960889583010343 1.80954075490745e-11 83.6629119915083 13.6185816391001 6.14329114504151 2.88441518957381e-09 -80.6819588789744 40.145569153157 -2.00973508611048 0.0454540160059249 C12orf66 other 2.12602943294076e-07 1 3.66378417379665e-05 6.14329114504151 -2.00973508611048 0.877218726386474 7.59979518598003 24.0521666675868 0.31597133393482 0.752266587713407 -29.251763448712 93.8757925726294 -0.311600708202603 0.755582696726583 SNX31 other 1 1 1 0.31597133393482 -0.311600708202603 1.79195393751466e-87 806.65607662857 27.8033671652427 29.0128915621767 6.0975126535671e-84 249.586359431265 76.1266097765872 3.27856921730442 0.00118395314311699 PIGG other 2.86192963360467e-83 1 9.73833745901201e-80 29.0128915621767 3.27856921730442 1.27641362592544e-25 3454.68365310821 303.340474277718 11.3887988780071 8.15357412691317e-25 -487.803536294866 939.526965878172 -0.519201208704976 0.604044190027668 PRPF8 essential 1.96248594986037e-21 1 1.27358827862384e-20 11.3887988780071 -0.519201208704976 0.232845095296342 30.220180884253 49.3903739689077 0.611863779433566 0.54114086596598 -159.975514448681 123.124651323052 -1.29929719783685 0.19494621913939 ADCY6 other 1 1 1 0.611863779433566 -1.29929719783685 0.000713734876561197 3.24394528592326 0.857818131074409 3.78162359643792 0.00019157844869337 -0.0587202553068367 5.27438874777638 -0.0111330920254205 0.99112542244227 REP15 other 1 1 1 3.78162359643792 -0.0111330920254205 2.08843631940612e-27 625.429777436685 59.6320800266793 10.4881429116152 7.99489100560895e-22 -698.513819258254 184.696576841166 -3.78195325113663 0.000191478833183214 PITPNA other 3.23791166960725e-23 1 1.23433122235597e-17 10.4881429116152 -3.78195325113663 3.84149489547499e-09 392.211677513993 82.7134052349641 4.74181514350469 3.42164653805275e-06 -521.935615271522 206.238178989889 -2.53074196944451 0.0119463715590522 DDX23 essential 4.0089840729177e-05 1 0.0364473789233378 4.74181514350469 -2.53074196944451 6.72153871839331e-09 63.1306658745348 14.0537584151152 4.49208418202464 1.04506751668236e-05 -96.0901206850099 32.7219187647025 -2.93656742368859 0.00360364956500633 ZNHIT2 other 6.92049626445775e-05 1 0.107182124510943 4.49208418202464 -2.93656742368859 9.82184663040364e-06 294.482119143583 98.6380008398626 2.985483450964 0.00308805848009582 -823.852273256764 287.137253601846 -2.86919326183688 0.00443683279896881 ZBTB4 other 0.0805293205226795 1 1 2.985483450964 -2.86919326183688 2.31623591599125e-07 137.43715476079 26.3665891629859 5.2125496366336 3.689047691919e-07 -51.8256132384621 76.7524643609039 -0.675230608814966 0.500102857050094 TNK1 other 0.00216660707581821 1 0.00421104794032554 5.2125496366336 -0.675230608814966 1.5115826403995e-07 124.809481447743 23.0060320689681 5.42507639186044 1.2990006286897e-07 -36.0080032136212 79.7788311238058 -0.451347841355831 0.652105244066368 ZHX3 other 0.00143041065261005 1 0.00152684533896188 5.42507639186044 -0.451347841355831 0.059285320855559 -17.8399195224615 108.07698182446 -0.165066781300733 0.869013579753824 -711.002523021216 297.812401818803 -2.38741744359528 0.0176478518643336 PHLDA3 other 1 1 1 -0.165066781300733 -2.38741744359528 0.000118743603719048 23.5484190613457 5.46831034532115 4.30634283247923 2.31695123429345e-05 12.99161062654 16.3818913817001 0.793047049564295 0.428439087451753 SLC16A11 other 0.871221820486656 1 0.230907360009686 4.30634283247923 0.793047049564295 4.98027496860616e-16 110.779344203225 12.3599314898349 8.96277979326442 5.1194166410303e-17 79.7588388041821 37.0277183197872 2.15403061337322 0.0321130200613417 SLC16A13 other 6.75972721488915e-12 1 7.66325476995826e-13 8.96277979326442 2.15403061337322 0.31583014201339 8.23468031177445 11.5011464679426 0.71598777867295 0.474613117356119 -15.569474045953 20.3609091044325 -0.764674797480611 0.445128114016978 GLIS1 other 1 1 1 0.71598777867295 -0.764674797480611 0.340985145811071 -107.185773095546 73.0458719450261 -1.46737618761281 0.143433319488256 -108.154591433355 128.215688017248 -0.843536334015585 0.399672498685918 PODN other 1 1 1 -1.46737618761281 -0.843536334015585 9.59809242435725e-13 59.3084219167175 9.00379053348757 6.58705038684909 2.33635623339294e-10 -78.2428409464659 32.8465029950702 -2.38207522299129 0.0179081863217007 SNHG11 other 1.18411666239295e-08 1 3.08492477057204e-06 6.58705038684909 -2.38207522299129 1.8205624103577e-09 34.8756058857294 7.93936187059673 4.39274672878819 1.60916389571031e-05 -28.7130772908064 14.46805824016 -1.98458402739252 0.0482028919808945 C11orf45 other 1.94035541695924e-05 1 0.162439902252992 4.39274672878819 -1.98458402739252 2.36232763561992e-10 146.436938816012 21.3918960042967 6.84543991736867 5.11830415237718e-11 -24.767507476713 56.9383190214048 -0.434988385719679 0.663918338371774 EXO1 other 2.64060983109595e-06 1 6.90408047114157e-07 6.84543991736867 -0.434988385719679 2.71665822988236e-13 63.1311755489833 15.0048719055113 4.20737850656326 3.54330965989292e-05 -97.787553141063 28.1562459962713 -3.47303234792071 0.000601191350160993 RALGAPA1 other 3.4153827266081e-09 1 0.347244346669506 4.20737850656326 -3.47303234792071 3.44231778470338e-10 35.2491200350025 14.2685886913583 2.47039989710762 0.0141213826342516 -125.607382621064 26.1275610675995 -4.80746680855828 2.55529350085533e-06 LIG4 other 3.81443233722982e-06 0.0397731433408132 1 2.47039989710762 -4.80746680855828 0.000828492943217043 20.2372148997707 12.6939722153034 1.59423815938193 0.112061319187906 -122.60998188569 43.1280629067836 -2.84292809882738 0.00481415989146034 GTF2IRD2B other 1 1 1 1.59423815938193 -2.84292809882738 0.000213709558532929 1251.26614947187 562.034962021901 2.22631372427524 0.0268154838641956 -3251.00935517901 1201.03359946139 -2.70684296978614 0.00722403599878368 ATP2A2 essential 1 1 1 2.22631372427524 -2.70684296978614 1.51483133070547e-13 220.428335753605 30.4939058954556 7.22860287263019 4.98028075581082e-12 -27.2738965249399 61.3085298121283 -0.444863000442469 0.656773859831362 ZWILCH other 1.92004871166918e-09 1 6.90217109947822e-08 7.22860287263019 -0.444863000442469 1.55541666192699e-14 6669.55823342678 867.153247532491 7.69132590162719 2.7052458430073e-13 -184.621713214676 1743.42673287886 -0.105895882937286 0.915743302705172 RPL4 essential 2.02904103548375e-10 1 3.85849214588132e-09 7.69132590162719 -0.105895882937286 1.58755433431259e-15 158.308545388538 23.3217821187584 6.78801236468142 7.15299618558348e-11 -110.74866645841 46.888849831236 -2.36194035164055 0.018886925683725 SNAPC5 essential 2.12827534057945e-11 1 9.60075148029014e-07 6.78801236468142 -2.36194035164055 3.46749032002635e-07 64.2328791796933 14.6420937328942 4.3868643618495 1.64819561239595e-05 -63.2922530137529 31.28923950995 -2.02281212343387 0.0440743995039971 C12orf76 other 0.00320846879312038 1 0.166189380698045 4.3868643618495 -2.02281212343387 1.60853006527342e-07 822.673139047263 145.114468114089 5.66913244240042 3.68220505164012e-08 496.131816976331 385.364147903154 1.28743636292034 0.199044711558761 CNTNAP2 other 0.00151829152861158 1 0.000444663082036061 5.66913244240042 1.28743636292034 0.83673051603638 2.16694959931373 3.72171186197401 0.582245396655821 0.560939007467486 1.13171197577397 9.89309659613402 0.114394109546673 0.909019457970553 LINGO2 other 1 1 1 0.582245396655821 0.114394109546673 5.74708426246691e-07 78.8018390556556 24.7280085164637 3.18674425411937 0.00160666411330049 -225.792192717638 66.7234787903775 -3.38399910812505 0.000819552389192862 BBS1 other 0.00522007663559869 1 1 3.18674425411937 -3.38399910812505 1.70093623644672e-10 332.399293574242 51.5596479697751 6.44688834510854 5.23590832132363e-10 16.409604673277 103.826646237943 0.158048104873489 0.874537031185959 DENND4A other 1.91338317237891e-06 1 6.83131006088245e-06 6.44688834510854 0.158048104873489 0.0327112665608948 21.0869817089841 14.3196336216783 1.47259226500465 0.142021442518466 -96.7537547789103 53.3645165297398 -1.81307282574161 0.0709268650748576 GCSAM other 1 1 1 1.47259226500465 -1.81307282574161 0.014289621460688 17.7982648057337 7.1309681202597 2.49591142543006 0.0131859682423095 -36.4405190494153 31.6990048323118 -1.14957927676866 0.251377617224396 ANKRD36C other 1 1 1 2.49591142543006 -1.14957927676866 0.667627178541049 -7.95641579976309 32.6906174479781 -0.24338530198839 0.807889710661919 77.3932174607931 92.4342704490215 0.837278393444738 0.403168461881999 SLC26A9 other 1 1 1 -0.24338530198839 0.837278393444738 0.422972291941373 6.38376402029198 22.7423766580597 0.280699071881286 0.779153826238752 -80.3151970332635 64.3051480446912 -1.24896994214904 0.212745952564029 MFSD4A other 1 1 1 0.280699071881286 -1.24896994214904 7.89516912334639e-06 47.5555843531772 14.5742594348169 3.26298461790587 0.00124330964283919 -103.521272667003 39.3256614109066 -2.63241021137136 0.00896270454887043 PELI3 other 0.0652614679735813 1 1 3.26298461790587 -2.63241021137136 0.000263384974058712 10.7181380397508 2.76531933054148 3.87591332450277 0.000133319820860729 -8.45591819514693 7.96930307369599 -1.06106118903384 0.289606792147738 TMEM81 other 1 1 1 3.87591332450277 -1.06106118903384 6.2974895495595e-10 413.02392785714 65.1543612549082 6.33916010996157 9.56390661013949e-10 -80.3985710694395 175.80573212752 -0.457314844609973 0.647809809117473 MRPL11 other 6.88252632871357e-06 1 1.23651748562493e-05 6.33916010996157 -0.457314844609973 0.809309396074089 -6.31334851120723 77.211197133799 -0.0817672662200387 0.934892592554231 -260.341204815992 400.068657196243 -0.650741316854242 0.51576892777209 IL20RB other 1 1 1 -0.0817672662200387 -0.650741316854242 0.630520892385823 10.7649266925985 11.4194845895543 0.942680609459864 0.346680813938892 -3.48747744562014 33.6143578760785 -0.103749637535156 0.917444489507795 GOLT1A other 1 1 1 0.942680609459864 -0.103749637535156 2.30653659140289e-45 635.791797985651 40.9852168511106 15.512710358355 2.81350043033535e-39 -273.627726023796 109.020743187877 -2.50986847110599 0.0126609242936242 AKIRIN1 other 3.66877710228544e-41 1 4.46896408354466e-35 15.512710358355 -2.50986847110599 4.43974211202746e-14 188.357734110592 24.1633941900816 7.79516870141975 1.41363936088843e-13 -210.364917934926 123.780596350379 -1.69949833929914 0.0903813271713232 MSL2 other 5.7232715566146e-10 1 2.02305928936743e-09 7.79516870141975 -1.69949833929914 0.000168734631085282 15.2211682060322 5.44531668406042 2.79527694882976 0.0055632771378819 -24.9884482084636 13.1619801000811 -1.89853259300321 0.0587081759463732 ZNF497 other 1 1 1 2.79527694882976 -1.89853259300321 0.0709922525839791 16.7337724842567 8.6060467937395 1.94442034598624 0.052894888794339 1.57099864311639 12.5851965977507 0.124829090345492 0.900752787886779 TRAM1L1 other 1 1 1 1.94442034598624 0.124829090345492 0.964300280777702 -9.69495903251727 36.3343110156579 -0.266826554887454 0.789806384103947 -9.26839545451942 77.331711220083 -0.119852455199678 0.904689160230932 CMKLR1 other 1 1 1 -0.266826554887454 -0.119852455199678 8.83588613459991e-10 120.958442843316 18.5062008284573 6.53610343714181 3.1202455259962e-10 -28.3227572857297 50.4425100975334 -0.561485882264108 0.57493037585442 ANGEL2 other 9.57456621545246e-06 1 4.10281084213241e-06 6.53610343714181 -0.561485882264108 0.0200141235313045 208.112658635843 74.3245196924005 2.80005386509241 0.00547972316140213 154.681114112988 104.206760443933 1.48436736209847 0.138882300789101 UGT8 other 1 1 1 2.80005386509241 1.48436736209847 0.0031940540983339 45.2060229259761 26.8571496034616 1.68320255847811 0.0934917397427076 -91.9873712842437 53.2026661345852 -1.72899927705777 0.0849522736733977 IQCK other 1 1 1 1.68320255847811 -1.72899927705777 0.177677496772984 70.048838198738 81.4630014145359 0.859885309679233 0.39060673970243 -610.622929598509 410.005301826614 -1.48930495990692 0.137561400958782 SLCO2A1 other 1 1 1 0.859885309679233 -1.48930495990692 2.34156457182006e-23 268.669762770761 27.1101755787058 9.91029224398651 5.62855608211223e-20 -67.0843672013943 71.5488737925306 -0.937602000499937 0.349277709747313 ZNF266 other 3.54583123110711e-19 1 8.61788221732203e-16 9.91029224398651 -0.937602000499937 3.22216373232414e-06 202.579442478453 40.606259703519 4.98887225658208 1.08463015241286e-06 28.7524217884979 108.676519107027 0.264568850978581 0.791541983385752 SLC29A2 other 0.0274882788004573 1 0.0119981787459911 4.98887225658208 0.264568850978581 0.000447547247335042 52.5870833973275 21.8185608929951 2.41019944694019 0.0166052744971625 -22.367023196773 32.8442353766408 -0.681003011343678 0.496446798334955 BRSK2 other 1 1 1 2.41019944694019 -0.681003011343678 0.0104020156626796 64.1995415210302 21.9084978030177 2.93034885815802 0.00367426668476025 4.38189574931951 56.2854714009064 0.0778512756535064 0.938003807119852 B4GAT1 other 1 1 1 2.93034885815802 0.0778512756535064 3.12329431005613e-06 406.858601553826 98.9812677105318 4.11046060496693 5.23255506819842e-05 -105.70926243568 155.204322245376 -0.681097413437717 0.496389281538758 TMEM167A other 0.0266760567021894 1 0.504418308574328 4.11046060496693 -0.681097413437717 0.680149721432614 5.32587958132992 7.36585004117966 0.723050232024132 0.470270303481368 -3.65711471671051 19.8322985842279 -0.184401959317964 0.853835540112607 LEP other 1 1 1 0.723050232024132 -0.184401959317964 0.273239296275859 131.820480685816 123.652381516009 1.06605694989182 0.287343246835172 -110.007125776681 200.390174853429 -0.548964667839345 0.583480051556717 SH3PXD2B other 1 1 1 1.06605694989182 -0.548964667839345 8.45526265390751e-08 150.157051700212 28.7373205684939 5.22515839089175 3.53636722015788e-07 -303.55511737349 186.18074219564 -1.6304324163372 0.10420257725867 KIAA1551 other 0.000813396267305903 1 0.00404489682641658 5.22515839089175 -1.6304324163372 6.24289084197862e-21 128.883856208154 33.0794836109533 3.896187066399 0.000123393127075497 -287.739312967397 51.3306044026868 -5.60560929129321 5.13712408700821e-08 LARP7 other 9.23323555528637e-17 0.00081351497041862 1 3.896187066399 -5.60560929129321 0.0265449962570758 42.8877654330531 22.5463412403672 1.90220510617778 0.0582005603448007 -11.0809588935176 32.422758699517 -0.341764838587985 0.732791768112876 FGFBP3 other 1 1 1 1.90220510617778 -0.341764838587985 0.0335053586326666 186.71153248705 75.3937637681056 2.47648509844041 0.0138814148979936 -2.46206171563985 203.072083933836 -0.0121240776572817 0.990335576152656 NR1D2 other 1 1 1 2.47648509844041 -0.0121240776572817 1.7750213448176e-09 292.520629853059 53.1034063904744 5.50850971220428 8.40953192380705e-08 -246.556295752948 136.428808974299 -1.80721577507427 0.0718375487676407 BRMS1 other 1.892705259979e-05 1 0.000997706867440468 5.50850971220428 -1.80721577507427 2.75197925170338e-11 3946.45688502916 597.144029500967 6.60888611467356 2.05815781816474e-10 -1263.14816233052 1608.39937441494 -0.785344848066724 0.432939997744451 RPL15 essential 3.20688142200995e-07 1 2.7238656456451e-06 6.60888611467356 -0.785344848066724 3.36633622596433e-06 300.334250755552 99.6449736737897 3.0140431542364 0.00282022649791283 -176.897277075203 160.643539953826 -1.10117890284321 0.271788743439666 HRAS og 0.0286677193003122 1 1 3.0140431542364 -1.10117890284321 0.667324206013615 3.1312886513434 3.89717592677884 0.803476340348722 0.422441964701987 -13.4885845831136 35.5773621472102 -0.379133914630917 0.704901474628801 WDR49 other 1 1 1 0.803476340348722 -0.379133914630917 9.46933697874658e-40 1062.59260603892 76.2883743714427 13.92863086668 2.71384009293904e-33 -203.113347942808 168.08421515456 -1.20840227475279 0.227994690197229 SRP72 essential 1.50212092493857e-35 1 4.29546609910392e-29 13.92863086668 -1.20840227475279 0.443327413631264 1.19627010323324 1.66380379769639 0.718997098629974 0.472759936345964 -2.17797449115454 3.70972520925078 -0.587098603886729 0.557624481663457 PCP2 other 1 1 1 0.718997098629974 -0.587098603886729 0.0272795348213533 106.127481868881 43.9857114499037 2.41277174724686 0.0164959446660545 -49.575340089587 113.004393369274 -0.438702767312644 0.661226461581828 RIN1 other 1 1 1 2.41277174724686 -0.438702767312644 1.70382679143722e-28 74.6928217769557 8.69186697719991 8.59341519755034 7.00020117410384e-16 -63.5902725518741 17.144181427738 -3.70914603417518 0.000252606750897374 THAP6 other 2.65234716623033e-24 1 1.03532975364996e-11 8.59341519755034 -3.70914603417518 1.40456622743457e-09 112.012122905971 22.0505269169548 5.07979348193463 7.28782964579307e-07 -81.341551574402 48.5699495948002 -1.67472999772498 0.095208336837999 CEP135 other 1.50541408256437e-05 1 0.00815653893957161 5.07979348193463 -1.67472999772498 0.0133408914919805 165.533239343607 56.5883439363026 2.92521794823923 0.00373569388370794 207.680334764173 116.044481698045 1.78966144469127 0.074633133578247 FZD4 other 1 1 1 2.92521794823923 1.78966144469127 0.287755795121315 -135.986284177601 86.4681853716095 -1.57267419910781 0.116961015276292 -140.865911907189 222.146795210744 -0.634111834805243 0.526542719976305 CD248 other 1 1 1 -1.57267419910781 -0.634111834805243 0.177567595853276 23.0650428812914 15.8450783554575 1.4556597552796 0.146648431658513 -7.78176921676393 31.4439979519278 -0.247480273617269 0.804724644677918 BTC other 1 1 1 1.4556597552796 -0.247480273617269 0.977588900010558 -1.8581521341718 11.1923243465469 -0.166020218556755 0.868263923589449 -4.86231954078219 24.9020660041169 -0.19525767620961 0.845336470471888 ADGRE1 other 1 1 1 -0.166020218556755 -0.19525767620961 1.83697212489388e-10 163.807642711207 26.898176361914 6.08991630165483 3.82237109438459e-09 -83.0010159765079 64.0839097524689 -1.29519276050897 0.196347939953229 DENND6A other 2.06273599904334e-06 1 4.83300601173987e-05 6.08991630165483 -1.29519276050897 1.53740372687148e-06 132.080585917003 26.447649087318 4.99403880779475 1.0562469087473e-06 -6.44011879109858 63.010545193557 -0.102206999976205 0.918667402842622 PDE12 other 0.0134922551070241 1 0.0116947657736502 4.99403880779475 -0.102206999976205 3.78422988479352e-23 81.4497968111567 9.73245150505559 8.36888802054108 3.05104548659566e-15 -36.6099581038669 17.2192073685485 -2.12611169145545 0.034391336788872 GLMN essential 5.72062031684237e-19 1 4.4761888333845e-11 8.36888802054108 -2.12611169145545 0.619175795206095 20.349124697161 22.6857756958038 0.896999290217126 0.370509622122339 -4.78762741573511 54.0480210551789 -0.08858099375826 0.929479858773262 DNAH12 other 1 1 1 0.896999290217126 -0.08858099375826 5.12156076504479e-09 300.235027295262 60.4156297063705 4.96949264212674 1.19120920148103e-06 -368.585369421594 155.121641681274 -2.37610539333332 0.0181917712188272 YIF1A other 5.31105851335145e-05 1 0.0131366550739328 4.96949264212674 -2.37610539333332 0.802326706616585 2.66697738133308 11.1931950985619 0.238267747309768 0.811853495920666 -14.9660873085532 28.7393644291459 -0.520752201930236 0.602964620376967 CNIH2 other 1 1 1 0.238267747309768 -0.520752201930236 0.811180319265786 -8.63900879296577 21.1364493996127 -0.408725639279985 0.683066210431554 -19.3261191047163 29.8810262710868 -0.646768920497771 0.51833298174513 AMY1B other 1 1 1 -0.408725639279985 -0.646768920497771 1.53864917416241e-09 383.509962033894 97.7142714687198 3.92481012516849 0.0001100270355445 -455.870987246981 183.995905843756 -2.47761484233293 0.0138340032395562 NDUFA11 other 1.64573915668412e-05 1 1 3.92481012516849 -2.47761484233293 2.60219558054813e-14 195.983854819262 23.5209647956143 8.3323050955718 4.73827801681141e-15 -106.82976157927 159.274200992506 -0.670728598313902 0.50299342362283 RSRC1 other 3.37660898531926e-10 1 6.93826050001695e-11 8.3323050955718 -0.670728598313902 0.0288779660090654 13.7601343658589 5.34714960996755 2.57335877421661 0.0106266306829665 -21.6242996101755 36.2400061270972 -0.596696908227251 0.551228958629612 PQLC2L other 1 1 1 2.57335877421661 -0.596696908227251 2.28519921612492e-17 938.442852315274 139.647189813591 6.72009836766467 1.06797307673724e-10 -1538.31306600532 358.554590018229 -4.29031759411337 2.48497730898768e-05 RAB1B other 3.20202114163424e-13 0.378511743705004 1.42585085475189e-06 6.72009836766467 -4.29031759411337 1.91052979254745e-10 112.882163589674 28.6368645326094 3.94184787448126 0.00010288906006746 -73.3422641142039 46.000541323621 -1.59437828346909 0.112012615852869 PTDSS2 other 2.14437863915525e-06 1 0.963736707623243 3.94184787448126 -1.59437828346909 1.23046012816836e-12 163.474295819123 33.6160123785162 4.86298892261233 1.95504398249486e-06 -160.002895424646 64.6113680938158 -2.47638921980914 0.0138782650706878 C19orf70 other 1.51100503739075e-08 1 0.0212454629577716 4.86298892261233 -2.47638921980914 3.98022610527279e-11 33.548888620833 4.6425447610401 7.2264006805864 5.33177820298581e-12 30.2695599478439 31.4430375638233 0.962679254076601 0.336589440026683 C3orf33 other 4.60949985251642e-07 1 7.38451281113535e-08 7.2264006805864 0.962679254076601 0.0185718144388336 345.473843652363 152.110731668028 2.27119967055537 0.0239342547734355 -112.084359620456 301.630810970677 -0.371594530610972 0.710490582386425 SEZ6L2 other 1 1 1 2.27119967055537 -0.371594530610972 0.541540539777597 13.6077552929124 17.5387339580736 0.775868732910931 0.438515765607151 -10.678672629585 34.7787594547782 -0.307045817533262 0.759048733237018 ASPHD1 other 1 1 1 0.775868732910931 -0.307045817533262 1.26129774143469e-05 109.146071207575 33.0775177421046 3.29970562055334 0.00110002677333805 -96.4263348468059 65.5916804293765 -1.4701000830529 0.142716463772528 KCTD13 other 0.102379537672254 1 1 3.29970562055334 -1.4701000830529 0.618006203698325 0.364393798719866 3.19079909955017 0.114201423327227 0.909163631658405 -20.4891504124965 21.1929254881603 -0.966791980840161 0.33451965594818 P2RY14 other 1 1 1 0.114201423327227 -0.966791980840161 0.211592999386739 -0.973628962368945 2.37397994136725 -0.410125184886019 0.682036961572192 -11.4461654887888 6.47612386783822 -1.76744079056808 0.0782756611281671 AMZ1 other 1 1 1 -0.410125184886019 -1.76744079056808 0.408416782066432 -2.55904440724602 2.08938963747895 -1.22478084572763 0.22172924213632 -8.55586526285594 13.8751641370543 -0.616631643297616 0.537999223228791 GPR171 other 1 1 1 -1.22478084572763 -0.616631643297616 0.0372413744305327 9.52879612088243 3.90412196784879 2.44070144307835 0.0153115890836627 25.1424179396461 25.8300254265496 0.973379527292421 0.331249030777457 GPR149 other 1 1 1 2.44070144307835 0.973379527292421 0.050987510474593 4.51394742123224 7.08423170441568 0.637182352239926 0.524543986094897 -16.3108807232726 10.2908542461462 -1.58498802267857 0.114135238402074 CD164L2 other 1 1 1 0.637182352239926 -1.58498802267857 0.00450752925668789 45.0105978664477 19.7704067219025 2.27666524516075 0.0235803965384224 -51.9406420876712 41.1651744747557 -1.26176173793514 0.208111506014359 FUT1 other 1 1 1 2.27666524516075 -1.26176173793514 6.55458784350632e-15 358.623880646925 41.9756953472051 8.54360785879879 1.02489008014815e-15 -101.148392902239 272.664592441775 -0.370962698150249 0.710960580158116 DHX36 essential 8.64419044801613e-11 1 1.51263526929065e-11 8.54360785879879 -0.370962698150249 0.0126780472535894 6.5619746283957 2.34027744348593 2.80393021206127 0.00541895301003626 -7.67860071758067 13.7142013770384 -0.559901412154913 0.576016110694008 ZIC4 other 1 1 1 2.80393021206127 -0.559901412154913 5.08042423811301e-05 62.8536554478921 21.1485804080385 2.9720035215225 0.00322339728296369 -108.62420237578 44.6786546821287 -2.43123261317063 0.0156937912509484 FBXW8 other 0.388906475427551 1 1 2.9720035215225 -2.43123261317063 0.00106525125079221 167.599770025786 51.9571469098071 3.22573081845168 0.00141067648684229 -114.779479904472 133.403855341668 -0.860391025510499 0.39033406343624 KLC2 other 1 1 1 3.22573081845168 -0.860391025510499 0.49178745571508 5.33078500476161 11.0273323568244 0.483415646891482 0.629188126350633 -19.4540404145726 21.8285026786377 -0.891221935877954 0.373594905999335 SLC22A1 other 1 1 1 0.483415646891482 -0.891221935877954 2.93044281209021e-20 393.519137698413 78.661984496354 5.00265967376722 1.01387573164482e-06 -511.781247265878 109.621176819111 -4.66863485793794 4.75968825916096e-06 CTBP2 other 4.29632220680546e-16 0.0737132920696258 0.0112408402367462 5.00265967376722 -4.66863485793794 2.56832108364718e-06 469.38271140456 97.5866587490695 4.80990657351546 2.51761712535643e-06 1373.26896164347 538.426288311652 2.55052361196858 0.0113106363394685 CHST2 other 0.0220978346037004 1 0.0271172540572142 4.80990657351546 2.55052361196858 0.000144738299520997 24.9199905615468 11.3782750744486 2.19013781952836 0.029360290738221 -63.0425451675325 22.5335528770463 -2.79771882896241 0.00551280623916087 ZDHHC14 other 1 1 1 2.19013781952836 -2.79771882896241 1.74265155175247e-11 159.18887182227 22.1929556825869 7.17294596082904 7.22980927518213e-12 -104.23358111915 119.949159347329 -0.868981339146598 0.385637792302737 ATR ts 2.04866116424021e-07 1 9.97930574253389e-08 7.17294596082904 -0.868981339146598 1.24593373312694e-10 3408.96178213834 591.313218168612 5.76506947146628 2.20331137580448e-08 -2158.53563080189 1524.18273765016 -1.41619215169023 0.157859200969573 LRRC75A-AS1 other 1.41089535939295e-06 1 0.000268848054075663 5.76506947146628 -1.41619215169023 3.70734803366017e-14 491.611476896569 66.0742599889987 7.44028729157802 1.33239321337878e-12 -326.609528559984 216.429514276439 -1.50908035649341 0.132443221747765 UBE2C other 4.79063512909567e-10 1 1.87201246479718e-08 7.44028729157802 -1.50908035649341 6.76929302280989e-09 123.288368881884 20.4793163850924 6.02014083690948 5.7143699858133e-09 -147.242252835202 108.363679812535 -1.3587786340398 0.175359224461933 GK5 other 6.9683102376805e-05 1 7.16810571020421e-05 6.02014083690948 -1.3587786340398 1.87701944247925e-15 73.9633514205047 15.3955502009724 4.80420319215569 2.58459274397858e-06 -252.888841097582 49.4338705937132 -5.115699783576 5.95020854690117e-07 VCPIP1 other 2.51088890820449e-11 0.00934242243948953 0.0278231408889295 4.80420319215569 -5.115699783576 0.639443418211864 81.2106754791964 130.35831579588 0.622980398169296 0.533823245142565 -50.5559024214831 193.412165542873 -0.261389464719459 0.79399145826784 DES other 1 1 1 0.622980398169296 -0.261389464719459 2.22860888353567e-10 83.3395425607163 23.9033742038621 3.48651792211206 0.000570690161478321 -99.3893539259611 34.4012323999574 -2.88912190035623 0.00417534233614821 PDIK1L other 2.49403620156477e-06 1 1 3.48651792211206 -2.88912190035623 0.314462432741462 8.16556739548809 11.1895529654005 0.729749206312088 0.46617147434013 -73.5985157326521 58.7594161782885 -1.25253994201268 0.211449010184191 SPSB4 other 1 1 1 0.729749206312088 -1.25253994201268 1.4868382760815e-06 3.9884401892674 0.947393413892968 4.20990913677388 3.51038085367022e-05 -2.22129391997929 2.10102916014941 -1.05724088085542 0.291371794731596 RAG2 other 0.0130559269022716 1 0.344157738893829 4.20990913677388 -1.05724088085542 3.25128181856934e-16 49.3792343414083 9.96114909404217 4.95718253739845 1.2805580472097e-06 -101.73962519888 22.1024575176575 -4.6030910869346 6.47372640318688e-06 TRAF6 other 4.43312275961929e-12 0.0999478619388023 0.0140938218675899 4.95718253739845 -4.6030910869346 0.00895845593017004 46.0697599935944 23.592404076065 1.95273698454212 0.0521307289841654 -63.9540671644288 48.9424969609741 -1.30671851939685 0.192685130758547 ZNF654 other 1 1 1 1.95273698454212 -1.30671851939685 3.03887864392529e-07 55.3579545454544 11.7472276533909 4.71242715122448 3.91095641440121e-06 -29.4700413223143 30.5310897269664 -0.965246952724555 0.335278534334621 TVP23C other 0.00282220659661342 1 0.0415148023388688 4.71242715122448 -0.965246952724555 5.04048380184664e-15 174.142461130663 20.4766628968089 8.50443561083389 1.28330146649425e-15 -61.5833507818418 105.531795532202 -0.583552572675126 0.560010330788458 MRPS22 essential 6.67259245688458e-11 1 1.89145803146588e-11 8.50443561083389 -0.583552572675126 0.00579266838501879 143.538492772363 93.428778520153 1.53634131844505 0.125621375224423 -562.072469538498 245.382642113038 -2.29059588200038 0.0227548951812781 PACS1 other 1 1 1 1.53634131844505 -2.29059588200038 0.472686275128692 6.05690187399277 12.1762816983569 0.497434440500019 0.619284596576168 -39.2455348249992 41.6093883989319 -0.943189417944115 0.346421019352996 WFDC5 other 1 1 1 0.497434440500019 -0.943189417944115 9.82297800360432e-10 2265.56039585557 519.498793614269 4.36105035026849 1.84768081403318e-05 -1337.62978452262 742.466667787312 -1.80160247261875 0.072731795881674 MARCKSL1 other 1.06127454350941e-05 1 0.185673445002194 4.36105035026849 -1.80160247261875 2.31848040521105e-07 181.430455229802 35.292517527354 5.14076263018589 5.43806707370888e-07 -172.605864950413 95.0226647157372 -1.81647047540466 0.0704677158794101 SH3BP5L other 0.00216847472299389 1 0.00613468346585099 5.14076263018589 -1.81647047540466 2.9272192761092e-07 65.8989714240763 22.9856456931639 2.86696194241239 0.00446972684849389 -90.907345285155 35.7330384097133 -2.54406983931273 0.0115124788925167 TMEM51-AS1 other 0.0027208503171435 1 1 2.86696194241239 -2.54406983931273 0.00370377930359726 50.0552800764742 18.6642450262672 2.68188078360677 0.00777041634274358 -48.8587827896123 39.93203553496 -1.22354851524754 0.222185380381345 YPEL2 other 1 1 1 2.68188078360677 -1.22354851524754 6.76450751892647e-06 133.528012710909 74.7731352895442 1.78577522787895 0.0752496347399705 -510.942081672817 141.393558616448 -3.61361639577109 0.000359620255280527 ABO other 0.0561521769146086 1 1 1.78577522787895 -3.61361639577109 6.75272906000978e-36 2216.36559778113 148.646002578795 14.9103612564776 5.04927869894476e-37 1297.7882792591 1616.23444641045 0.802970312965055 0.422703429734217 PSMD2 essential 1.06787657354995e-31 1 8.01270036735544e-33 14.9103612564776 0.802970312965055 0.564570237772317 1.43638429562296 2.20675550791314 0.650903233490197 0.515753096256792 7.06457419165597 7.06964187178876 0.99928317724933 0.318698638436887 FAM182B other 1 1 1 0.650903233490197 0.99928317724933 0.00372350254141491 26.842253035236 8.08088355817408 3.32169778737676 0.00101721753914227 5.74132458252905 17.220000526524 0.333410244307813 0.739081499466634 PPM1E other 1 1 1 3.32169778737676 0.333410244307813 3.68801140448108e-34 209.837678512413 14.5893513024459 14.3829341114868 3.5087026550253e-35 217.209287189486 158.636029125836 1.36923048557391 0.172069332645546 FAM131A other 5.81894439399025e-30 1 5.56304805954261e-31 14.3829341114868 1.36923048557391 0.0882669798025228 94.0134860297322 77.886475980267 1.20705789864663 0.228470182425902 -259.936427614481 184.65473701961 -1.40768892155134 0.160377720561192 CSRP2 other 1 1 1 1.20705789864663 -1.40768892155134 1.85178463557627e-32 345.373275523639 24.7342513749271 13.9633607780724 1.3862410412306e-33 64.2095551485861 281.029516318172 0.228479755400107 0.819449503326686 PARL other 2.91526455178771e-28 1 2.1948354405804e-29 13.9633607780724 0.228479755400107 4.08315149852363e-08 327.0381933403 60.1648317592575 5.43570361251744 1.21077902594969e-07 -101.55560634625 161.132196668149 -0.630262656664473 0.529049943185791 DDIT3 og 0.000400720488065109 1 0.0014248447577376 5.43570361251744 -0.630262656664473 0.000826518199217759 72.4677801844864 41.1288113866668 1.7619711764386 0.0792057715304289 -168.595786495874 74.602856914384 -2.25991059148524 0.0246238394098391 PCCA other 1 1 1 1.7619711764386 -2.25991059148524 7.03981072634864e-09 441.785104256576 96.1539495821453 4.59456014210997 6.63180306592606e-06 -668.51020419752 257.517500863045 -2.5959796983004 0.00994278378531055 DCTN2 essential 7.23974135097694e-05 1 0.0691100197500155 4.59456014210997 -2.5959796983004 7.42937148228263e-18 82.8017235412199 13.604869101572 6.08618303660505 4.00075107584345e-09 -113.224302623382 29.1841865570639 -3.87964565680095 0.000131831064886205 ZNF408 other 1.05014165902065e-13 1 5.05374875900544e-05 6.08618303660505 -3.87964565680095 0.00032620144122827 467.819622962247 233.699695945609 2.00179816695665 0.0462993969620222 -1607.76095311181 605.791490840586 -2.65398404801116 0.00842310837715056 CTDSP2 other 1 1 1 2.00179816695665 -2.65398404801116 2.36724162779185e-12 1013.28285108282 162.292043229179 6.2435768933658 1.68306685357483e-09 -427.217369131718 350.410765499273 -1.21919019389433 0.223852035405943 CKAP5 essential 2.87643530192988e-08 1 2.15685017285615e-05 6.2435768933658 -1.21919019389433 3.47511039532477e-07 257.454175915557 115.949316549389 2.22040270333025 0.0272311309056093 -897.099502100733 248.726133274624 -3.60677621723901 0.000369946110933651 ARHGAP1 other 0.00321517213775448 1 1 2.22040270333025 -3.60677621723901 6.97865928177973e-11 125.776020599487 45.5082678718112 2.76380592980985 0.00610778555202973 -322.165932364672 79.3860686502698 -4.05821749133281 6.48621035563165e-05 MED16 other 7.99544993913503e-07 0.974682830140767 1 2.76380592980985 -4.05821749133281 3.91829226707162e-17 354.458704125702 66.073670257316 5.36459837549973 1.76467102766364e-07 -627.34933613955 141.784323451879 -4.42467348199091 1.41003031287689e-05 ATG13 other 5.46288307875125e-13 0.2162422487828 0.00205637114853644 5.36459837549973 -4.42467348199091 0.404565921570735 1.34563578353414 13.0166318114993 0.103378185925591 0.917738724368593 -21.7956000929701 20.3828514656977 -1.06931064721979 0.28587426189019 C1orf127 other 1 1 1 0.103378185925591 -1.06931064721979 0.296560506596009 83.4199585512165 61.2781276318169 1.36133334641744 0.174569121843865 -6.4942336484752 131.679836148433 -0.0493183606422074 0.960702878700455 CHST1 other 1 1 1 1.36133334641744 -0.0493183606422074 0.00467907655298287 431.544043223571 224.883885658046 1.9189638330946 0.0560509228296725 -532.073054450568 400.561752892214 -1.32831717109482 0.185203386603621 GOLGA8A other 1 1 1 1.9189638330946 -1.32831717109482 0.00295475377728571 -111.357584256478 172.111728639911 -0.647007528984026 0.518187102849595 -1118.67210735073 341.473283056827 -3.27601649340328 0.00119317135414443 TP53I11 other 1 1 1 -0.647007528984026 -3.27601649340328 1.37444339305711e-13 108.251572858168 16.4311021869854 6.5882112852972 2.29526224865976e-10 -12.3926022885614 26.3239542514096 -0.470772824257502 0.63818027933471 CENPS other 1.74444355446809e-09 1 3.03158237802981e-06 6.5882112852972 -0.470772824257502 4.19438403069008e-26 167.129573484215 20.525723658698 8.14244487859468 1.42317545653284e-14 -182.178325557176 38.2525974712874 -4.7625086294838 3.11842016619185e-06 DOLK essential 6.46480410650262e-22 0.0484508941221228 2.06901247870745e-10 8.14244487859468 -4.7625086294838 0.32640865831123 -30.8408003939331 22.5620218413304 -1.3669342495466 0.172778763865697 -0.195357637205257 42.0475279695719 -0.0046461146859009 0.996296368413551 PHYHD1 other 1 1 1 -1.3669342495466 -0.0046461146859009 0.74108202644087 0.215051515168366 2.93832507303711 0.0731884695610226 0.941710131123596 -4.97457237408793 6.99221937002 -0.71144397949198 0.477421085287842 CATSPER1 other 1 1 1 0.0731884695610226 -0.71144397949198 0.000501992981836236 90.8606093352092 24.2989256418098 3.73928504801342 0.000225653559096264 -17.2132831498136 87.379895696268 -0.196993633520082 0.843981832377333 CCNE2 other 1 1 1 3.73928504801342 -0.196993633520082 1.31215537707448e-11 161.925989119513 38.6176183367579 4.19305995795666 3.72270304805714e-05 -231.421277244535 65.1709364415823 -3.55098898190569 0.000451865089233021 PHYKPL other 1.55031157801349e-07 1 0.364043131069507 4.19305995795666 -3.55098898190569 0.3202874530537 -46.2309777323324 40.3215750027405 -1.14655684281158 0.252576149350804 -123.795980205283 95.9517040340471 -1.29019053336828 0.198084303562516 CST6 other 1 1 1 -1.14655684281158 -1.29019053336828 7.6032346789254e-06 46.3938667057722 10.7235203146567 4.32636534873366 2.20222920862174e-05 -14.5920482954148 24.4558236282851 -0.596669673334491 0.55127442368097 ZNF519 other 0.062886354029392 1 0.219782475020449 4.32636534873366 -0.596669673334491 4.73853110322346e-23 216.975430096895 28.3312640010488 7.65851569802404 7.65140166921521e-13 -215.10380322856 60.1784226767653 -3.57443405228384 0.000439026725077959 LSM1 other 7.15755123141904e-19 1 1.0802248876598e-08 7.65851569802404 -3.57443405228384 5.12414517218696e-13 919.270760279421 132.358069939348 6.94533216373332 2.79754480203635e-11 -478.344659816501 314.967417628773 -1.51871156520795 0.130000856028352 BANF1 essential 6.38007315388998e-09 1 3.79906584116537e-07 6.94533216373332 -1.51871156520795 1.03786136761585e-10 98.5740804017097 61.8476682342994 1.59382048209608 0.112137572264599 -438.040171143334 96.3030010989355 -4.54856199853336 8.14334399164114e-06 TMEM9B other 1.17973701656894e-06 0.12553779097514 1 1.59382048209608 -4.54856199853336 0.0947606164009046 18.3284746510915 31.6903637921506 0.578361131203907 0.563498878780601 -65.6793948860743 49.345063867883 -1.33102259350449 0.184296168311612 NRIP3 other 1 1 1 0.578361131203907 -1.33102259350449 1.03700937273125e-24 321.472727441102 33.8997919912161 9.48302949836388 1.97833149169475e-18 -206.334799599941 76.9388421641571 -2.68180276432682 0.00780850480516727 PTPN2 other 1.58465402247062e-20 1 2.99915054140925e-14 9.48302949836388 -2.68180276432682 0.382245229085995 107.65530450949 162.585775246302 0.662144670075855 0.508439116341351 -146.093806241299 253.162302463856 -0.577075673666529 0.564365645049608 SCUBE2 other 1 1 1 0.662144670075855 -0.577075673666529 4.16580561020859e-13 121.551004601355 20.659934606332 5.8834167153705 1.18192369421787e-08 -162.53049578487 49.1636532197665 -3.30590761956486 0.00107441964483407 EIF1AD essential 5.20350778771155e-09 1 0.000146322153344173 5.8834167153705 -3.30590761956486 3.13971917718074e-29 792.582180560473 86.3981010973745 9.17360648548511 1.24009143667212e-17 -638.562015710029 147.380671818359 -4.33273921085821 2.08170403308421e-05 SMAD2 ts 4.90361341092088e-25 0.317709669529312 1.86770171277187e-13 9.17360648548511 -4.33273921085821 3.18925116448581e-23 550.520593014552 90.8770963703567 6.05785852544169 4.57609420556101e-09 -516.617782403731 137.569986905361 -3.75530879972482 0.000211755885460119 EIF3F essential 4.82406131140123e-19 1 5.76404826132465e-05 6.05785852544169 -3.75530879972482 3.44821851012499e-06 7.91270385696271 15.0070704045179 0.527265058647329 0.598471575853342 -103.418128978484 25.4690906562485 -4.06053480174454 6.53279592966867e-05 ZNF25 other 0.0293408913026535 0.981487260473421 1 0.527265058647329 -4.06053480174454 0.00214986113739796 93.6609981600872 26.8853006383274 3.4837251559897 0.000575788512594784 46.1296922824421 44.753143353316 1.03075870935497 0.303566298600624 ARL10 other 1 1 1 3.4837251559897 1.03075870935497 4.30767992749125e-11 208.410834756221 159.485017886525 1.30677374914618 0.192389281532472 -1511.42032801706 265.478000941776 -5.69320366529558 3.21565965595725e-08 CLTB other 4.98140106815088e-07 0.000509842838452023 1 1.30677374914618 -5.69320366529558 0.156468192292489 -10.1833760870921 148.029072081433 -0.0687930819527805 0.945204869769755 -446.112159794781 261.096459957917 -1.7086105260358 0.0886638712016019 PCSK1 other 1 1 1 -0.0687930819527805 -1.7086105260358 0.210781266359157 -136.834965680084 193.948591106178 -0.70552183390274 0.481089319356904 -554.955873922355 322.373262811701 -1.72146991683521 0.0863025701058241 LPL other 1 1 1 -0.70552183390274 -1.72146991683521 2.17792498532353e-06 11.0167716157955 2.74745227318293 4.00981364565528 7.84834336360455e-05 -4.63162045989744 4.78443149671963 -0.968060774424932 0.333870847962313 RFESD other 0.0188586524479164 1 0.744572334905163 4.00981364565528 -0.968060774424932 1.89745526516551e-07 292.432619990937 55.60362956859 5.25923617324667 2.93221265501136e-07 -271.653869923232 217.320412253971 -1.25001543622034 0.212368314317053 CCDC14 other 0.00178455667688817 1 0.00336999200440456 5.25923617324667 -1.25001543622034 0.319724762572225 -29.3036313432255 19.6189425947154 -1.49363969040405 0.136446197916528 -39.1207805880322 57.3367601364042 -0.682298415448725 0.495639557612754 TBC1D10C other 1 1 1 -1.49363969040405 -0.682298415448725 4.46171208660561e-11 541.980066352872 89.1753856966246 6.0776868204046 4.12172814701903e-09 -391.06838124559 212.207241778203 -1.84286067699014 0.0664414540925907 SART1 essential 5.1564006584901e-07 1 5.20326961279683e-05 6.0776868204046 -1.84286067699014 3.61465978734529e-18 190.990025307129 34.139548718174 5.59439220722494 5.44356429073973e-08 -132.313031569843 47.2923317279809 -2.79776925212505 0.00551750687613979 PPP2R2D other 5.13534715988145e-14 1 0.00065295553667423 5.59439220722494 -2.79776925212505 0.0150391763613353 57.6164912736066 31.3519090611659 1.83773470257265 0.0671961392325316 -58.7367387404552 54.5415186691366 -1.07691791819674 0.282474663842822 MCTP1 other 1 1 1 1.83773470257265 -1.07691791819674 7.0850603521881e-05 117.808324748699 51.9845666100492 2.26621731084943 0.0242357093956158 -451.17728983483 151.925956871814 -2.96971827016701 0.0032507609530384 POLD4 other 0.533859297537373 1 1 2.26621731084943 -2.96971827016701 0.0773888000173869 -23.3532632030913 13.1728413021963 -1.77283417201706 0.0773753369650632 14.4982556891371 30.2196019214849 0.479763291614685 0.63178126661308 LRRC25 other 1 1 1 -1.77283417201706 0.479763291614685 0.343378806327875 22.8861692824418 15.9258710208806 1.43704349058431 0.151863435668977 5.70825787828137 48.3648767509802 0.118024861464486 0.906135713361785 DPP10 other 1 1 1 1.43704349058431 0.118024861464486 0.559425156962745 2.80432122546168 15.64677201135 0.179226822211473 0.85789502772742 -43.9250214828028 45.7280105384187 -0.960571452062166 0.337633513882071 CLCF1 other 1 1 1 0.179226822211473 -0.960571452062166 3.93794333981188e-10 15.2456625691207 3.14283520695945 4.85092649317435 2.07526146043444e-06 -20.7290868169567 8.16577127548114 -2.53853385279093 0.0116918237592188 LIPT2 other 4.35339636216203e-06 1 0.0224916837081885 4.85092649317435 -2.53853385279093 0.0359095725242483 -20.8121488860502 76.8678970565663 -0.270752156400672 0.78678775829723 -504.144465520953 203.384193423263 -2.47877898982925 0.0137922119164715 KCNE3 other 1 1 1 -0.270752156400672 -2.47877898982925 0.298285842694057 2.11459039815469 2.8525781089614 0.741290971669342 0.45916852011298 -8.99332105417176 8.29918406604267 -1.0836391846 0.279502387024181 CABP4 other 1 1 1 0.741290971669342 -1.0836391846 8.81213971334363e-05 53.5701961822306 16.3853993339553 3.26938606074846 0.00122800334247156 -82.3978753019814 46.0787303347894 -1.78819760664653 0.074945465843761 ALG10B other 0.657561865409701 1 1 3.26938606074846 -1.78819760664653 2.23510939259376e-06 337.311028386136 85.2847051550024 3.95511748294238 9.77213241617367e-05 -413.551657571397 202.94873866181 -2.0377148451291 0.0425496311182212 DRAP1 other 0.0193292260271509 1 0.917896397851193 3.95511748294238 -2.0377148451291 0.00713039525562086 3.24239764176439 1.40211814631504 2.31249959233882 0.0214996403604874 -4.90899129351938 3.85584578456506 -1.27312957203062 0.204063094029594 UCP3 other 1 1 1 2.31249959233882 -1.27312957203062 0.0120401751324943 24.163738677442 168.80740320074 0.143143832671292 0.886282962687223 -1287.40606567728 464.222872905248 -2.7732499642258 0.0059352482982043 UCP2 other 1 1 1 0.143143832671292 -2.7732499642258 1.01124869422854e-11 139.955041623368 24.8070918648632 5.64173512904187 4.23312078335237e-08 -172.162033126421 59.0324841328989 -2.91639485708979 0.00383735350108422 C11orf68 other 1.19923982648563e-07 1 0.000510091054393961 5.64173512904187 -2.91639485708979 3.23773406303471e-28 209.617449182495 19.0230376075529 11.0191365599398 1.50388046592148e-23 -117.52039530759 51.6535435349138 -2.27516617960887 0.0236829835240804 PAAF1 other 5.03629533505049e-24 1 2.34018839302041e-19 11.0191365599398 -2.27516617960887 7.61899684800584e-19 195.4942480387 22.617992228914 8.64330688861001 4.97587528465883e-16 -99.9026051816399 61.4149785313303 -1.62668143131688 0.104975582734377 MRPL48 other 1.0953831768378e-14 1 7.37673510950671e-12 8.64330688861001 -1.62668143131688 8.6115425343572e-27 1283.25483811217 121.555135769896 10.5569775393231 5.16541657236075e-22 -792.317188826913 330.153782203104 -2.39984283548051 0.01708487852366 RAB6A other 1.33143059123697e-22 1 7.98005206264012e-18 10.5569775393231 -2.39984283548051 0.00921254618476999 13.0538252091911 22.2796672340074 0.585907548442463 0.558438200728278 -135.505512020188 52.414969268423 -2.58524451910387 0.0102678403462639 P2RY2 other 1 1 1 0.585907548442463 -2.58524451910387 0.00701531172317548 265.947668574546 99.7130810818948 2.66712918394451 0.00810882912557994 -196.89411780961 237.301178939429 -0.829722459406184 0.407423315966485 FOSL1 other 1 1 1 2.66712918394451 -0.829722459406184 3.37199113786277e-18 73.4085248465155 10.6573099683792 6.888091372431 3.96870250360938e-11 -53.0066112018244 21.5840186095093 -2.45582679299911 0.0146864505503139 ERCC4 other 4.79463419892707e-14 1 5.36687639563096e-07 6.888091372431 -2.45582679299911 0.0122564110921858 25.7599034998058 9.99727645222212 2.57669212439154 0.0105026709920856 -17.9997239831349 27.7408192032163 -0.648853368434339 0.516980610623455 SUGCT other 1 1 1 2.57669212439154 -0.648853368434339 5.60203833251032e-06 123.267821527387 26.6710680731299 4.62178046973582 5.88253546020986e-06 -30.0492233187449 63.4728746585355 -0.473418345716978 0.636294471134737 CCDC85B other 0.0468554486131163 1 0.0615136733074146 4.62178046973582 -0.473418345716978 5.62149663653089e-09 122.893196680177 20.7594518382737 5.9198671351043 9.8290822096918e-09 -25.7343551650181 68.841913745923 -0.373818125684255 0.708835189127117 TMEM70 other 5.81318967183659e-05 1 0.000122077201044372 5.9198671351043 -0.373818125684255 6.61154402907089e-10 17.4523570128522 3.55561189480231 4.90839763427627 1.59076312235705e-06 -15.2900217384221 6.81508539300746 -2.24355541518382 0.0256718860619367 LINC00476 other 7.21914492534251e-06 1 0.0174029485585861 4.90839763427627 -2.24355541518382 6.90537014952013e-13 372.017493532858 52.8812996071224 7.03495368488924 1.66298253110697e-11 -197.945690722396 154.601959802355 -1.28035693063305 0.201526677868326 RPS6KB2 other 8.56611167047972e-09 1 2.27396231303567e-07 7.03495368488924 -1.28035693063305 1.28405098819169e-14 328.560087780666 45.0124618913034 7.29931387832279 3.29253877740246e-12 -16.7319596739156 87.6816618728884 -0.190826215157416 0.848806226996101 RMI2 other 1.67876826196182e-10 1 4.58551875528841e-08 7.29931387832279 -0.190826215157416 1.92700295799733e-06 153.541617210683 79.4576310992376 1.93237093890855 0.0543519966811273 -694.528071216616 200.451546044554 -3.46481773237231 0.000616300818470846 TOM1L2 other 0.0167764877523248 1 1 1.93237093890855 -3.46481773237231 2.85553219477488e-10 25.1521244630117 8.16491871673538 3.08051131133224 0.00227901616181245 -44.7998803500269 13.7523226205614 -3.25762284568903 0.00126667398363781 ZNF77 other 3.17735067312601e-06 1 1 3.08051131133224 -3.25762284568903 0.0158637340021876 15.1778918680276 7.70177769923912 1.97069981252862 0.0497758612644539 -51.523091835371 29.6720123414361 -1.73642054480479 0.083625925618037 GPR156 other 1 1 1 1.97069981252862 -1.73642054480479 1.99559793686421e-18 109.892566755983 29.8037420386755 3.68720701626589 0.000273876032703893 -225.078651944933 42.9600980196599 -5.23924903155317 3.2435192799126e-07 KDF1 other 2.84971385384209e-14 0.00510465064272645 1 3.68720701626589 -5.23924903155317 2.49289907592441e-05 50.3737436030176 12.6905147992862 3.969401115694 9.33762318037614e-05 -24.930279233671 27.3792896758702 -0.910552447810303 0.363377866081672 B3GNTL1 other 0.196963955988788 1 0.87829683634618 3.969401115694 -0.910552447810303 0.000594596001130738 276.382199208697 104.714106039502 2.63939797284271 0.00878462355222857 -424.115455449787 218.691743289167 -1.9393299859931 0.0534951292962818 MLXIP other 1 1 1 2.63939797284271 -1.9393299859931 0.725984646173368 -35.3611347759414 59.2987381656924 -0.59632187580679 0.551457993994506 -72.6426485850156 96.0179246211702 -0.756552996449574 0.449974904208112 NR2F1 other 1 1 1 -0.59632187580679 -0.756552996449574 2.81936284222599e-12 370.127135765413 85.4628239269811 4.33085543816861 2.11159314461776e-05 -391.386754955966 134.065798930244 -2.91936316405058 0.00381009450567196 AURKAIP1 essential 3.41368452936723e-08 1 0.211032618873099 4.33085543816861 -2.91936316405058 1.90230004962092e-09 19.2367940364491 3.28412054695243 5.85751764024019 1.35271261063011e-08 -1.34619902241415 6.29612984324179 -0.213813732551775 0.830852502178816 TTLL11 other 2.02575932284132e-05 1 0.000166951790403968 5.85751764024019 -0.213813732551775 7.30432149729334e-22 828.361771056721 89.4858382613114 9.25690351849627 7.96191797052389e-18 -155.350548086534 218.492844783195 -0.71100977352684 0.477713087120945 TOMM5 other 1.09170389098546e-17 1 1.20089608749412e-13 9.25690351849627 -0.71100977352684 5.12881814904902e-28 129.88429941635 10.7703122510787 12.059473893465 4.44253124137032e-27 -53.7127078891387 45.5264093488906 -1.17981428048745 0.239112550939568 SLC35E3 other 7.9727478126967e-24 1 6.97432979582727e-23 12.059473893465 -1.17981428048745 0.00121917948552401 65.7905457310225 20.4159740221791 3.22250340148112 0.00142488975046942 -9.02868505335981 41.5131704843987 -0.217489653235542 0.82798923075782 PRIMA1 other 1 1 1 3.22250340148112 -0.217489653235542 0.000296629001308987 12.2892274840497 3.75519505966663 3.27259364394794 0.00120495853364036 -6.02073718235424 7.14172126255581 -0.843037268049243 0.399956576115295 ZNF169 other 1 1 1 3.27259364394794 -0.843037268049243 2.60800664806798e-22 709.763135175992 70.7367098349161 10.0338726077651 2.36658938357707e-20 -649.199582998042 268.216833735014 -2.42042818102693 0.0161599892134072 RUVBL1 essential 3.91487877941484e-18 1 3.6277448660853e-16 10.0338726077651 -2.42042818102693 0.265388141249085 -2107.41014332904 2208.50468257239 -0.954224892507087 0.340820187760892 -5197.81090905942 3183.41158358799 -1.63278004511155 0.103676576862973 SFN other 1 1 1 -0.954224892507087 -1.63278004511155 3.45603864347337e-07 9.7468131888762 12.7810774416771 0.762597146707941 0.446369398744334 -89.9645981316309 22.6020114783055 -3.98038016297722 8.8490128575975e-05 MSRA other 0.00319821816067025 1 1 0.762597146707941 -3.98038016297722 1.51467725878744e-29 601.439282446921 48.8479072549647 12.3124882158753 5.74291924743269e-28 -139.757951579623 146.148321020244 -0.956274766647948 0.339785707573901 CTDNEP1 other 2.36880376501767e-25 1 9.02729476503944e-24 12.3124882158753 -0.956274766647948 0.000287032752141099 257.935345264396 99.0652264837024 2.60369207662217 0.00973098823372678 -360.811126424667 198.369449773555 -1.81888454515826 0.0700326592244804 ETV4 other 1 1 1 2.60369207662217 -1.81888454515826 2.06580324865956e-12 111.046807716706 19.7700719697685 5.61691469239533 4.80010458682293e-08 -90.7003321019444 36.8046742586439 -2.46436991846607 0.0143440258414004 SWI5 other 2.51676809784194e-08 1 0.000577452581794799 5.61691469239533 -2.46436991846607 0.0109028315305326 -7.94321529096029 7.15714817921163 -1.10982965450287 0.268056262854246 -38.4192256081289 12.9179061979987 -2.97410625369621 0.00320308463925213 GAPT other 1 1 1 -1.10982965450287 -2.97410625369621 0.000748985008425093 338.297548412657 95.8235091939606 3.53042328817132 0.000487650651217678 -71.5844732801753 213.137961055813 -0.335859801443019 0.737237433359624 BAIAP2 other 1 1 1 3.53042328817132 -0.335859801443019 0.813501302758599 8.72928491650798 14.1709152724289 0.616000078237132 0.538421219111925 11.9779677658562 23.6591414803481 0.506272291232772 0.613084853408211 CALCB other 1 1 1 0.616000078237132 0.506272291232772 0.142318638086048 15.987645015178 10.9895942547305 1.45479847977973 0.146882340643845 -42.8290699613294 42.1442523259269 -1.01624937204026 0.310417073809777 CREG2 other 1 1 1 1.45479847977973 -1.01624937204026 0.0371339106753488 26.3277142409526 10.781405200518 2.44195573316247 0.0152572266406829 -0.755710480965198 31.1133047427384 -0.0242889814249505 0.980640244781498 HOXD8 other 1 1 1 2.44195573316247 -0.0242889814249505 5.49766633419417e-16 124.838992816189 23.3089125201163 5.35584801343477 1.87444532293792e-07 -394.158198482164 77.4303161596843 -5.09048933326442 6.85831111009891e-07 ZDHHC21 other 7.45318624926704e-12 0.0107606901317452 0.00218054224417369 5.35584801343477 -5.09048933326442 0.0470489969179444 27.6472707338086 20.9600731376638 1.31904457356727 0.188259522239663 -33.9693267549011 30.4252623177327 -1.11648426889989 0.265196601272398 TSPEAR other 1 1 1 1.31904457356727 -1.11648426889989 7.16908595316068e-05 100.017952528994 28.0450201385194 3.56633555743541 0.000428361633276511 -156.851594868759 100.9267448353 -1.55411328409255 0.121333096115078 PLEKHF2 other 0.539975553992062 1 1 3.56633555743541 -1.55411328409255 0.412696818247838 -2717.4832263996 2069.93742544937 -1.31283351515308 0.19034969605237 -162.569013756408 9396.30090052488 -0.01730138439344 0.986208911971072 A2M other 1 1 1 -1.31283351515308 -0.01730138439344 0.228197123822445 100.692531938899 77.6817038140464 1.29621940553641 0.196002673969052 -78.3510382253389 155.550816265481 -0.503700591912137 0.614880995452112 ARL4D other 1 1 1 1.29621940553641 -0.503700591912137 0.000968696240752682 -2.60385593666754 10.4828091858023 -0.248392953693571 0.80401781713212 -50.7874569179597 16.5244193357618 -3.07347906670745 0.00233072551901898 DOK7 other 1 1 1 -0.248392953693571 -3.07347906670745 0.315917634803047 -0.805617921599414 48.0381766358292 -0.0167703684448036 0.986632524248758 -194.754104588073 135.117364457219 -1.44136991844403 0.150669791986706 LRRN1 other 1 1 1 -0.0167703684448036 -1.44136991844403 3.39150487529018e-15 421.893253528022 51.8797638932318 8.13213518851542 1.52393090138835e-14 -108.911946564948 115.456880941374 -0.943312738720614 0.346361157495487 UBE2O other 4.50832743072323e-11 1 2.21457638589755e-10 8.13213518851542 -0.943312738720614 0.00157490956677107 111.762207036152 56.7237610258102 1.97028908194749 0.0498423210364369 -197.810263047447 117.765271107728 -1.67969946646237 0.094189874351403 ORAI3 other 1 1 1 1.97028908194749 -1.67969946646237 0.00182378447730851 33.4087986362417 51.8763572196542 0.644008184591347 0.520110808217686 -174.599635134731 76.1865303855196 -2.29173889729878 0.0226821931708458 DENND2C other 1 1 1 0.644008184591347 -2.29173889729878 0.0622470231303508 2.89546102779392 5.13653294156415 0.563699495502936 0.573424814861701 -16.4536493916269 9.42884751962475 -1.74503292765961 0.0821126500205293 PLEKHD1 other 1 1 1 0.563699495502936 -1.74503292765961 0.00114352341157485 660.238757593718 216.485107719929 3.04981143759728 0.0025351759624937 -379.474829604385 491.333797507369 -0.772336101301262 0.440641994521144 TUBB6 other 1 1 1 3.04981143759728 -0.772336101301262 0.000173058381220137 19.4158203312726 33.054227779157 0.58739294897446 0.557428906826408 -177.198098548681 53.1393544140837 -3.33459261036333 0.000973438766896495 LYSMD3 other 1 1 1 0.58739294897446 -3.33459261036333 0.000123262715046911 29.2120706866888 9.68977455184219 3.01473171851404 0.00281404081766402 -44.9579164985166 23.0906977372483 -1.94701420503174 0.0525584039815346 AMIGO3 other 0.902899387718623 1 1 3.01473171851404 -1.94701420503174 1.3617773434911e-08 124.024667505392 38.4799510011788 3.22309837404919 0.00142872926633149 -158.504512426825 60.4128057331869 -2.62369063153365 0.00920843573724034 B3GALT6 other 0.000137539511692601 1 1 3.22309837404919 -2.62369063153365 3.01450898210179e-08 21.3332218692527 4.66353462589822 4.57447485235381 7.2507364914957e-06 -21.7027119101556 10.8855942422165 -1.99370943168065 0.047178649645325 ZNF613 other 0.000298556969587361 1 0.0753569043561148 4.57447485235381 -1.99370943168065 0.207090498231454 19.9014578169038 11.823236878407 1.68324952139377 0.0934741436333434 27.1468810485925 18.409961549088 1.47457565167687 0.141483144738828 C11orf16 other 1 1 1 1.68324952139377 1.47457565167687 0.153403998890228 10.5439489772632 249.030675363469 0.0423399605766396 0.966259694194883 -818.260609828903 491.636972951637 -1.66435938476376 0.0972270310066207 NUPR1 other 1 1 1 0.0423399605766396 -1.66435938476376 0.608896294428853 71.2441953302194 78.6778333637048 0.905518012943724 0.36598948322486 104.172069682393 132.2908930847 0.78744702113165 0.431703347286228 JAKMIP2 other 1 1 1 0.905518012943724 0.78744702113165 2.13434421698987e-08 22.3973825008811 8.97044168219295 2.4967981839001 0.0131260598721906 -52.1115640918847 14.4212559732375 -3.61352466030641 0.000359966794668222 MBLAC2 other 0.000213083351800405 1 1 2.4967981839001 -3.61352466030641 5.33569173300398e-17 107.482479748429 21.6617601877927 4.96185346050503 1.23992149502386e-06 -220.594918984417 40.8215868220785 -5.40387907863266 1.43732116781007e-07 TPRN other 7.41074224796922e-13 0.00226895519550497 0.0136602151106779 4.96185346050503 -5.40387907863266 0.10415080437689 -27.6697273580499 13.2981039425427 -2.08072725838232 0.0383980963340793 -30.553237305297 19.1383509417798 -1.59644043513686 0.111555901901912 ZNF683 other 1 1 1 -2.08072725838232 -1.59644043513686 3.72823261406193e-15 391.070550963922 68.8588057354165 5.67931068201464 3.49175830759299e-08 -343.901495790375 113.140005281855 -3.03961003832063 0.00260135018409668 SLC35A4 other 4.95109291147425e-11 1 0.000422223414554144 5.67931068201464 -3.03961003832063 0.00171805342874023 -98.7733747590055 74.7131712168391 -1.32203429663475 0.187271523033433 -376.955388226973 107.52562146448 -3.50572619895526 0.00053271763665064 CRYBG2 other 1 1 1 -1.32203429663475 -3.50572619895526 0.00152073593952335 136.347973697377 48.3725322203105 2.81870655595175 0.00517589892407213 -146.348102351513 115.029757483381 -1.27226298266913 0.204366259515474 IP6K1 other 1 1 1 2.81870655595175 -1.27226298266913 2.76165494317539e-16 243.850128767926 39.0918187359247 6.23788139444718 1.71334143708983e-09 -274.636839099312 73.6685319534097 -3.72800749271074 0.000235298248286248 SSNA1 other 3.77131599040031e-12 1 2.19496171505578e-05 6.23788139444718 -3.72800749271074 3.07099356771035e-09 173.942028134542 34.3518189779506 5.0635463655124 7.69683308439855e-07 -104.216917809066 76.5414175550512 -1.36157548603159 0.17448402071531 CSTF3 essential 3.22761423966358e-05 1 0.00859997558770178 5.0635463655124 -1.36157548603159 2.33978373514292e-15 781.504139320168 101.180093211747 7.72389226490096 2.60840129605836e-13 -171.855374369943 220.50785049456 -0.779361705193272 0.436492215584576 YES1 other 3.12173945942768e-11 1 3.72192780934567e-09 7.72389226490096 -0.779361705193272 1.62949437653321e-06 78.7641077707886 18.9892964083816 4.14781601576471 4.50030860003699e-05 -76.7393492149969 42.2374420683606 -1.81685598031234 0.0703478091664135 CHMP6 essential 0.0142727412440544 1 0.436889958891591 4.14781601576471 -1.81685598031234 6.73074040513025e-15 76.02273671243 13.7677566459374 5.521795501438 7.83452408895426e-08 -69.8204062488524 22.5724563850248 -3.09316828695582 0.00218643764866646 DLEU1 other 8.87111585396167e-11 1 0.00093175994989933 5.521795501438 -3.09316828695582 9.69700756092066e-17 14.3957068709523 1.62947838636587 8.83454913633939 1.25332051066626e-16 -1.95981325163602 6.96413843349054 -0.281415033654598 0.778605273086537 UFSP1 other 1.33818704340705e-12 1 1.86995420191405e-12 8.83454913633939 -0.281415033654598 7.28343607989407e-18 296.011293087305 33.6478081037448 8.79734252450045 1.67196545279894e-16 -271.727551868017 127.960369480853 -2.1235289720594 0.0346156078886184 TMEM39A other 1.02958652425383e-13 1 2.4922317039421e-12 8.79734252450045 -2.1235289720594 2.88575192783997e-19 114.198371076801 14.1210055189634 8.08712743036903 2.17372723120854e-14 -52.4567907338962 31.4638878487896 -1.66720625836181 0.0966502801697911 TCP11L1 other 4.17337443804216e-15 1 3.1510349943599e-10 8.08712743036903 -1.66720625836181 0.0029223658803381 2444.57963500622 923.401796421252 2.64736287548981 0.0085837675697626 -1041.64371630029 1714.82125487911 -0.607435739052419 0.544066690770538 GPX2 other 1 1 1 2.64736287548981 -0.607435739052419 3.10275003928197e-05 106.425642693198 28.6977179933051 3.7085054190729 0.000254118800599301 -81.2215615219305 64.3764487230493 -1.26166576648783 0.208182676087115 CCDC57 other 0.242697108072636 1 1 3.7085054190729 -1.26166576648783 0.690958736779054 4.61943672192014 19.4795296702921 0.237143134362487 0.812726249991095 -20.5064791298935 35.2842034433892 -0.581180163604787 0.561605670298355 FOXG1 other 1 1 1 0.237143134362487 -0.581180163604787 0.536390663863163 66.7512573292693 60.6689900383857 1.10025331371159 0.272198134470365 11.5161231564528 135.017043911589 0.0852938475233821 0.932090761496441 SPHK1 other 1 1 1 1.10025331371159 0.0852938475233821 3.10625756517122e-05 981.126203238776 216.445354993144 4.53290486769677 8.77567504071278e-06 594.908001811208 300.325955039503 1.98087441937197 0.0486275660203885 BNIP3 other 0.242939793156456 1 0.090529863719993 4.53290486769677 1.98087441937197 3.34556997053738e-16 43.6814002027551 6.81990206599225 6.40498936496088 6.61567027625296e-10 -56.3309750134177 16.8311912135217 -3.34682045369213 0.000933140093859533 MYPOP other 4.5603464268395e-12 1 8.59970979210122e-06 6.40498936496088 -3.34682045369213 3.55667887365215e-06 17.5757833016032 3.48249836850071 5.04688917030849 8.29849615037009e-07 -7.87660194984627 14.5681190946477 -0.540673912580802 0.589181432597213 LRRTM4 other 0.0302353271049169 1 0.00925365305727769 5.04688917030849 -0.540673912580802 2.78745782986529e-13 97.8582914418266 16.679492951813 5.86698239116375 1.31973859768054e-08 -73.5871039791292 33.3687888315306 -2.20526745368701 0.0282942454490006 ATAD5 other 3.50299825479171e-09 1 0.000163000914199523 5.86698239116375 -2.20526745368701 3.82936458884901e-16 171.486627351004 25.7359774260107 6.66330345696087 3.39360553264674e-10 -193.47415065972 66.3875042171276 -2.91431577284396 0.00403330565463968 SMIM19 other 5.21253107834127e-12 1 4.45580406436517e-06 6.66330345696087 -2.91431577284396 0.0108236207555625 5.42384645379501 3.5227200620402 1.53967569329189 0.12479767741864 -18.4764130624748 9.6765564909431 -1.90939959682642 0.0572587400545755 ZNF404 other 1 1 1 1.53967569329189 -1.90939959682642 2.38478723824003e-09 173.024078965204 28.948851809235 5.976889173546 7.22627596924591e-09 46.6685835637037 47.4416382725644 0.983705143055572 0.326147736939634 RTTN essential 2.52453577040089e-05 1 9.0241734303943e-05 5.976889173546 0.983705143055572 0.0272043294866062 6.41324312922232 3.82038009446554 1.67869242605284 0.0943604128988079 -5.14698033211862 6.43694263739415 -0.799600155238025 0.424640226480272 ACBD7 other 1 1 1 1.67869242605284 -0.799600155238025 5.80873925257919e-12 195.588373307304 32.7827235875447 5.96620267943859 7.62629640678789e-09 -125.718227994575 61.7790422196305 -2.03496563685197 0.0428347431584217 ANAPC2 essential 6.94434777645842e-08 1 9.51456739710857e-05 5.96620267943859 -2.03496563685197 6.76611036008495e-10 28.0411519191314 18.4322968423865 1.52130535651144 0.129357807330102 -121.871053462462 26.2660195425987 -4.63987522985008 5.45037296557742e-06 ZBTB8OS other 7.38114979181667e-06 0.084273666793758 1 1.52130535651144 -4.63987522985008 0.162646333028483 183.506054385116 97.2248501102682 1.88743982816113 0.0601657781014517 188.145174292904 164.605360520808 1.14300757701703 0.254040488656258 SLC35G1 other 1 1 1 1.88743982816113 1.14300757701703 0.638641332469521 32.7168714975389 35.459734786936 0.922648510884869 0.357017209038926 47.8708557313144 86.0716943833113 0.556174199593731 0.578554106285814 ZNF135 other 1 1 1 0.922648510884869 0.556174199593731 2.93582655075833e-06 571.184639422768 156.018571980905 3.66100414951033 0.00030178814864817 -757.311536946939 333.282598549504 -2.27228046181491 0.0238503089500883 COX8A other 0.0251248036213898 1 1 3.66100414951033 -2.27228046181491 0.00325767469098234 37.9107770098384 11.717301499316 3.23545289092814 0.00136877774680674 -1.79443534301137 23.3239535956633 -0.0769352989685681 0.938733070069335 ZSCAN2 other 1 1 1 3.23545289092814 -0.0769352989685681 0.754078140228462 0.306181922648022 5.37560494569626 0.0569576681584744 0.954621044026986 -7.04823256546223 10.1063509971741 -0.697406271307322 0.486148660341341 PRR18 other 1 1 1 0.0569576681584744 -0.697406271307322 1.78552938465824e-09 218.225768931295 37.4503928235438 5.82706221426077 1.58573934464763e-08 -100.117998018461 77.6781657862503 -1.28888210741174 0.198530167853 B3GNT4 other 1.90355287698415e-05 1 0.000195045939391659 5.82706221426077 -1.28888210741174 1.51784743554764e-23 57.4032105000232 7.55832001721234 7.59470495682911 4.97131130525789e-13 -57.96834687491 14.2879147376399 -4.05715935035636 6.49522743110922e-05 CDC26 essential 2.30166385126444e-19 0.975972873798472 7.0532964798999e-09 7.59470495682911 -4.05715935035636 1.35244896291651e-06 49.057185876447 22.3496812940372 2.19498368818061 0.0290194222514712 -108.05805001858 38.5916234627495 -2.8000389805545 0.00547996856507933 HSD11B2 other 0.0119231900570719 1 1 2.19498368818061 -2.8000389805545 6.78634523245535e-23 137.357965995432 18.8567713989694 7.28427805000274 3.73295548036839e-12 -158.745067745419 37.843121309938 -4.19481961980051 3.73239441764177e-05 CRLF3 other 1.02365231486357e-18 0.56564437399361 5.19254107319243e-08 7.28427805000274 -4.19481961980051 0.00202482674833467 231.765468621111 71.0762104103874 3.26080227523272 0.00125201426335954 -213.730167826144 194.273927260866 -1.10014849053395 0.272236568679221 RNPEP other 1 1 1 3.26080227523272 -1.10014849053395 2.38837375788346e-53 113.378242397137 5.8134211366531 19.5028434603331 1.81748109770394e-53 -9.03931435051656 43.9585735865755 -0.205632567506173 0.83723289049952 EID2 other 3.80444055893257e-49 1 2.89561088486192e-49 19.5028434603331 -0.205632567506173 1.47627467506847e-05 42.5466205970228 8.83385222731657 4.81631563469644 2.68584713283012e-06 45.0303257544655 25.1756581283006 1.78864542587055 0.0750172508044792 DMRTA1 other 0.119223942758529 1 0.0288809142193223 4.81631563469644 1.78864542587055 8.58047382988109e-36 19.8279217036298 1.33848114820348 14.8137474556463 8.90924820878842e-37 13.2839595407963 10.1169786818087 1.31303622935195 0.190281475659675 EID2B other 1.3568303267191e-31 1 1.41354132080637e-32 14.8137474556463 1.31303622935195 0.0498444183459937 40.6460244160053 16.513472275564 2.46138569391924 0.0144612160463276 39.1270442877845 66.7898822514768 0.585822926599327 0.55848027651814 RIMS2 other 1 1 1 2.46138569391924 0.585822926599327 1.97190374201234e-07 385.969642476557 67.7884469989216 5.69373779108255 3.28170184006067e-08 32.7950101236149 278.980616245574 0.117553006244516 0.90651055474545 KCMF1 essential 0.00185280075599479 1 0.000397217190720943 5.69373779108255 0.117553006244516 5.46045150570658e-18 88.932357542324 10.7621709430392 8.26342175877107 6.43167011130702e-15 -72.6345259433316 36.4991021690726 -1.99003596326482 0.0475953907631992 DNAJC30 other 7.73527560298394e-14 1 9.39924270066408e-11 8.26342175877107 -1.99003596326482 7.20706036945058e-10 220.529711350557 38.1257787252112 5.78426772447086 1.9904819129053e-08 -136.276381391785 100.711268537129 -1.353139359391 0.177130553180394 SPRYD4 other 7.85065086044252e-06 1 0.000243455842767447 5.78426772447086 -1.353139359391 2.00520945865032e-06 39.0453293136316 8.13890248411493 4.79737033215943 2.66236172867355e-06 -13.0205397462776 27.6024823322439 -0.471716260499789 0.637510298038042 VPS37D other 0.0174312858240472 1 0.0286363627536127 4.79737033215943 -0.471716260499789 0.823166133447282 -35.8711610801763 74.5550441619805 -0.481136608305691 0.630825626753105 -82.1182668461203 138.296032403143 -0.593786137021919 0.553173397317974 CLEC14A other 1 1 1 -0.481136608305691 -0.593786137021919 0.0603027407901174 -40.3159100139133 18.3913779589272 -2.19210926467551 0.0292191707290781 -3.50823552274165 41.0684219306063 -0.0854241618699045 0.931987028918273 SYNE3 other 1 1 1 -2.19210926467551 -0.0854241618699045 2.2750264588928e-06 210.782218076182 42.25895823313 4.98787066433015 1.09645925676791e-06 -172.860919461071 141.534160143388 -1.22133709124317 0.223027735167576 CLK2 other 0.0196539535783749 1 0.0121202606243125 4.98787066433015 -1.22133709124317 0.000124042221726293 159.914571787372 92.04099418041 1.73742768873099 0.0834605144038971 -409.338537632629 163.942835917145 -2.49683699408191 0.0131313644459732 LPCAT4 other 0.908113105258189 1 1 1.73742768873099 -2.49683699408191 1.85686266016575e-12 740.415295696838 101.290725936326 7.30980342822582 3.06040153030262e-12 -54.2919666529858 248.017925552503 -0.218903397938036 0.826891293549239 SLCO3A1 other 2.26611519046628e-08 1 4.26558765293579e-08 7.30980342822582 -0.218903397938036 4.12363255478634e-07 12.3357851068545 6.35822268976933 1.94013102540483 0.0533972293017827 -75.7411855290912 18.1561931784021 -4.17164461651521 4.07153014160762e-05 ZNF575 other 0.00379168013412604 0.616429663439394 1 1.94013102540483 -4.17164461651521 7.65506542903277e-11 27.4589718508857 6.2393469615603 4.40093683202047 1.55352594440392e-05 -42.5728009362181 13.7559111750349 -3.09487320719852 0.00217590224102224 WDR25 other 8.75433282464187e-07 1 0.157030402460349 4.40093683202047 -3.09487320719852 2.79142664967182e-09 50.5058356148576 12.0483843798366 4.19191768975937 3.77743584321565e-05 -53.402328745479 23.7859501317065 -2.24512068888491 0.0255884130117902 SGF29 other 2.94244283141906e-05 1 0.369055481882169 4.19191768975937 -2.24512068888491 0.585459740477615 121.025987301213 116.863268252096 1.03562042300697 0.301302480713209 88.5185518271715 242.468265290286 0.365072731151831 0.715341864345299 PLA2G16 other 1 1 1 1.03562042300697 0.365072731151831 0.928807743440959 5.94269162685672 28.8549063215091 0.20595082030909 0.836983958666204 -7.11422224592621 48.5142234153568 -0.146641989608232 0.88352363633211 DIRAS1 other 1 1 1 0.20595082030909 -0.146641989608232 0.000123621420572416 39.4042034267947 19.2366903827256 2.04838787976644 0.0414818438100786 -153.866657787702 54.9312415974134 -2.80107737078617 0.00545872832675014 PHLDB3 other 0.905156041431226 1 1 2.04838787976644 -2.80107737078617 0.0588772555227939 -21.6494483161967 19.9073069106796 -1.08751266122202 0.277769504327563 -129.559220980675 54.748057497041 -2.36646242631854 0.0186573205885573 PRR15 other 1 1 1 -1.08751266122202 -2.36646242631854 0.328377877211298 -20.6211831455224 14.3147013803463 -1.44055978518942 0.150863410080819 -12.0757000476617 24.0675403050111 -0.5017421761686 0.616256265749817 GNG7 other 1 1 1 -1.44055978518942 -0.5017421761686 1.12775801624727e-14 156.501848744874 19.7871807821913 7.90925450510499 6.53540880209129e-14 -119.584380355511 75.9313348762843 -1.57490159432006 0.116441533065524 USF3 other 1.47747577708555e-10 1 9.40053202092812e-10 7.90925450510499 -1.57490159432006 6.37834071302106e-07 90.4515836764721 23.6506226788895 3.82449058126528 0.000163055953012311 -82.2917330057848 44.3852553977 -1.85403310780654 0.0648330418586737 CNTD1 other 0.00576920917492755 1 1 3.82449058126528 -1.85403310780654 0.417699978448461 11.4069638319881 15.0287705398019 0.759008449944598 0.448514538007617 64.5431531647138 51.0078183660306 1.26535804181143 0.206842033577416 DCAF4L2 other 1 1 1 0.759008449944598 1.26535804181143 0.156340435657658 5.41566809997647 18.7328076250234 0.289100716154379 0.772738282958446 -41.5015588792922 31.0753585546788 -1.33551343603222 0.182894553182833 KBTBD11 other 1 1 1 0.289100716154379 -1.33551343603222 1.18272032767022e-17 519.983327003156 55.093657885521 9.43817032594984 2.39286107989082e-18 868.76388195187 600.933569242103 1.44569038312763 0.149482382628197 B3GNT5 other 1.6647971332286e-13 1 3.62494524992661e-14 9.43817032594984 1.44569038312763 0.781714154314661 -1.78555317795389 7.02659443081699 -0.254113595929611 0.799601213187339 -12.163057577435 17.324155850064 -0.70208659415807 0.483229947782303 MAP3K19 other 1 1 1 -0.254113595929611 -0.70208659415807 2.0563964334472e-18 174.26139807635 19.7926106641608 8.80436648975729 1.66644677697106e-16 -84.8052535815531 66.8184077318171 -1.26918998013135 0.205474424067508 RMDN1 other 2.93550590874587e-14 1 2.48417221043076e-12 8.80436648975729 -1.26918998013135 2.40397980133869e-14 330.433592428877 60.9983868940788 5.41708738958395 1.34858026241268e-07 -259.128594686056 96.8051974664427 -2.67680456698497 0.00789111942175414 MEX3C other 3.12156777203829e-10 1 0.00158309837004625 5.41708738958395 -2.67680456698497 0.0122570263194187 161.15051638541 89.1626224578921 1.80737748557715 0.0718041503191278 -187.349841153602 158.211228897766 -1.18417537401638 0.237373626329812 RNF152 other 1 1 1 1.80737748557715 -1.18417537401638 6.74598621745859e-08 300.2019593721 103.439831291499 2.90218918209672 0.00401362777737032 -657.723037559796 203.775261955841 -3.22768834277012 0.00140319440197819 MYO1D other 0.000652913266926615 1 1 2.90218918209672 -3.22768834277012 0.0173621759327322 25.6081389904186 15.1923281724753 1.68559674986577 0.0930160790826226 -22.845444094235 25.334158546529 -0.901764471564225 0.367976878528136 FOXL1 other 1 1 1 1.68559674986577 -0.901764471564225 1.85275267074535e-05 23.8720732035525 8.04000132651202 2.9691628438958 0.00325853144955687 -44.2002301171866 17.3731169890485 -2.54417386039874 0.0115196774597126 LRRC37A other 0.148294323766458 1 1 2.9691628438958 -2.54417386039874 0.237324509000646 8.16895079286321 14.5807687912373 0.560255149081891 0.57576486700077 -23.7602060605637 24.3143449834589 -0.977209383050532 0.329330638872939 FOXC2 other 1 1 1 0.560255149081891 -0.977209383050532 0.00183148819946482 46.4210666533612 15.4197073029029 3.01050245257392 0.00285881148928589 -9.55544635537133 29.8376708938091 -0.320247729435006 0.749031960496168 BDNF other 1 1 1 3.01050245257392 -0.320247729435006 2.9256676486811e-09 27.035645959937 4.18217603885462 6.46449257725202 4.66202857015706e-10 11.8971697051542 15.6428897221503 0.760548077527379 0.44758340413013 CCDC121 other 3.07955776700173e-05 1 6.09280513833826e-06 6.46449257725202 0.760548077527379 7.6703795819321e-18 130.024987296795 25.6032504422563 5.07845625265603 7.13440798993743e-07 -155.407108045858 42.335373033203 -3.6708571795027 0.000291698680531812 ACSF3 other 1.08367122733537e-13 1 0.00798911006713193 5.07845625265603 -3.6708571795027 0.000475831440718824 63.1114633772185 70.5121870355208 0.895043339748146 0.371567070859019 -327.326796524365 113.906123193423 -2.87365408766072 0.0043825568497741 BOK other 1 1 1 0.895043339748146 -2.87365408766072 0.103392512604291 0.313547450549564 1.64099506747734 0.191071537485833 0.848617527672416 -5.94064288652272 3.36545767864975 -1.76518127807988 0.0786982180886395 ZNF843 other 1 1 1 0.191071537485833 -1.76518127807988 5.72198925227409e-06 158.705619933023 32.200299204812 4.9287001628018 1.44637899246167e-06 72.4195302813894 107.054753075725 0.67647188191788 0.499320175677495 C8orf59 other 0.0478014982134977 1 0.0158580992733498 4.9287001628018 0.67647188191788 0.00178212480842101 38.7037749874995 24.0230801342544 1.61110793333749 0.108337682454594 -99.6276098125467 47.0790686621504 -2.11617631027275 0.0352553554279823 CDK5R1 other 1 1 1 1.61110793333749 -2.11617631027275 0.399745430315112 1.02694269225602 12.5446824844456 0.0818627887576541 0.934816477391322 -17.9311992195163 17.4313453738356 -1.02867557465937 0.304552786157573 TCERG1L other 1 1 1 0.0818627887576541 -1.02867557465937 0.793524501518649 -8.6084503601409 33.2417592082165 -0.258964945453703 0.795858157966745 -59.9633053507043 88.1454772697774 -0.680276597370743 0.496907951238536 NCKAP5 other 1 1 1 -0.258964945453703 -0.680276597370743 5.05119980358466e-14 175.271756245415 37.6148950877824 4.65963698254057 4.95646707947886e-06 -254.132213724935 61.8492389887561 -4.10889798936953 5.26077529751574e-05 RUFY1 other 6.49988390725274e-10 0.793482738124299 0.052156903077356 4.65963698254057 -4.10889798936953 1.05842167113808e-05 512.37722273144 106.171679058025 4.82593123964269 2.36454841959937e-06 -152.276201387985 725.902096727832 -0.209775122670681 0.834005599750665 BASP1 other 0.0864942189654041 1 0.0255158419958968 4.82593123964269 -0.209775122670681 0.44203575325243 64.9918449417063 51.9446983384245 1.25117378713566 0.211958116141867 84.5968272939878 86.9046707525311 0.973443965225815 0.331207223689985 DEFB103A other 1 1 1 1.25117378713566 0.973443965225815 0.000423046919597948 29.1425597713143 8.71982481206529 3.34210381508936 0.000948496737995277 -27.348556284334 19.3297288847462 -1.41484427678216 0.158262149109705 LRRC37A3 other 1 1 1 3.34210381508936 -1.41484427678216 0.0323641163129518 152.569245749382 58.7986937446894 2.59477270722808 0.0100555750538027 11.3438506478911 182.862775976775 0.0620347721798334 0.95058742507678 FKBP9P1 other 1 1 1 2.59477270722808 0.0620347721798334 0.00134783028035787 169.925328288447 54.5812773547286 3.11325305166618 0.00204927597592022 -104.328622301359 113.405119457314 -0.919963955777396 0.358412777022203 VSIG10 other 1 1 1 3.11325305166618 -0.919963955777396 0.00645218984727579 -6.14389173119472 14.3119187449708 -0.429284978532572 0.668054433860783 -72.4215638827435 25.6054435160662 -2.82836592294534 0.00502534409613198 IRX5 other 1 1 1 -0.429284978532572 -2.82836592294534 0.978627417591838 7.29487589007935 46.3014683193212 0.157551718225645 0.874933284501091 -7.01928452941882 99.8241692589467 -0.0703164832878358 0.943996235261229 METRNL other 1 1 1 0.157551718225645 -0.0703164832878358 1.57352921174694e-12 283.618929248123 37.7928973891376 7.5045563807352 9.04317820817249e-13 -110.530562729756 159.41433837098 -0.693353959620217 0.488685674352065 FAM91A1 other 1.92584240225708e-08 1 1.2751785591344e-08 7.5045563807352 -0.693353959620217 0.0112517482390772 264.566357190548 126.542452007245 2.09073202703074 0.0374871318031908 -378.224309242952 262.920960845923 -1.43854756968045 0.151436892252079 WSB2 other 1 1 1 2.09073202703074 -1.43854756968045 0.268874156539562 1.02755038320317 6.02314609284087 0.17060027556438 0.864666326120643 -16.2493093413022 11.3506187419399 -1.43157916856656 0.153425108778897 GRIN1 other 1 1 1 0.17060027556438 -1.43157916856656 0.170798868966163 51.5866910384893 28.7520708570596 1.79419045309646 0.0739056337419669 96.6080821787016 83.6472196506132 1.154946722464 0.249137156144265 SOX11 other 1 1 1 1.79419045309646 1.154946722464 5.85575551079388e-11 627.728074653272 98.1251818601076 6.39721692998433 7.77972520609823e-10 -109.960690412263 215.765461356078 -0.509630641165475 0.610761630634757 TYMS other 6.73119095965757e-07 1 1.00918841600786e-05 6.39721692998433 -0.509630641165475 3.65166807199411e-06 88.2976447030913 17.3487614774832 5.08956474026646 6.73387039750218e-07 20.4150073909229 35.7069110443633 0.571738265613588 0.567974967012689 PXMP2 other 0.031009965267374 1 0.00755540258599744 5.08956474026646 0.571738265613588 1.65222704979033e-09 171.792106814356 43.3734625070594 3.96076533632507 9.53963457557455e-05 -245.152427155646 84.7539983488921 -2.89251754408647 0.00412951292945629 PNMA1 other 1.76391759835616e-05 1 0.896821046449764 3.96076533632507 -2.89251754408647 0.0097375631298577 10.6894292179596 9.48578523398405 1.12688922996731 0.2607788430403 -42.190992812023 19.7509342968863 -2.13615174744794 0.0335565160621364 MAMSTR other 1 1 1 1.12688922996731 -2.13615174744794 0.00042972051309683 137.850333057413 111.699460317343 1.23411816552895 0.218231976817641 -788.127774902364 229.897834403414 -3.42816528458199 0.000702536147476024 ANKLE2 essential 1 1 1 1.23411816552895 -3.42816528458199 0.0723867027732789 -55.138724586526 37.237184722606 -1.48074364367971 0.139828064448946 -171.910481041539 77.5338225266051 -2.21723211160587 0.0274310144492963 FUT2 other 1 1 1 -1.48074364367971 -2.21723211160587 0.00620228544406719 -2.08193313666035 10.914420403125 -0.19075068210349 0.848863224803068 -49.5893372173514 17.0860195542027 -2.90233410186832 0.00400721119825046 GCNT4 other 1 1 1 -0.19075068210349 -2.90233410186832 0.317462850717777 298.818837192221 229.246980015463 1.30347992881767 0.193521326602118 1616.65201727539 1769.52607836891 0.913607342122682 0.361738306785612 MUC20 other 1 1 1 1.30347992881767 0.913607342122682 2.34382965996725e-11 236.362583439211 58.7471933946727 4.0233851147797 7.46795714879024e-05 -306.396737954662 94.9008296212749 -3.22859915110767 0.00139890207500811 THAP4 other 2.73853057470574e-07 1 0.710277404421439 4.0233851147797 -3.22859915110767 0.618136735413875 -19.2974913657836 22.2883008879617 -0.865812583147893 0.387361626657784 -55.6371829268034 83.1531299227249 -0.669093069358996 0.504007810078409 LY6H other 1 1 1 -0.865812583147893 -0.669093069358996 0.540395570965964 -32.983408467224 30.6854142398287 -1.07488881230134 0.283394895859638 -15.1322035643459 58.8374072854178 -0.257186784097067 0.797232672709625 FIBIN other 1 1 1 -1.07488881230134 -0.257186784097067 8.69640126042588e-05 153.557751168614 58.5888836163091 2.62093662979216 0.00926771084013826 -363.662960640333 140.653233029371 -2.5855286281574 0.0102495138282826 FAM89B other 0.649447246128604 1 1 2.62093662979216 -2.5855286281574 1.25092354701327e-05 197.334740799124 110.106857683829 1.79221117512743 0.0742228471186333 -725.960490291709 207.496372025189 -3.49866594392108 0.000547006172950932 DPP7 other 0.101574992017478 1 1 1.79221117512743 -3.49866594392108 3.10761034615646e-21 536.752001298483 112.479460492886 4.77200014070506 2.99103141533154e-06 -820.88243100745 176.288092526271 -4.65648257488019 5.05106226578304e-06 SEC24C other 4.61542288611157e-17 0.0781702396252584 0.0320429195524467 4.77200014070506 -4.65648257488019 8.82496445281728e-22 342.619993706527 38.609082493756 8.87407758943603 9.66341506096223e-17 -107.450654846516 95.7726032814423 -1.12193520030729 0.262879431088921 SMCR8 other 1.31774369209468e-17 1 1.44323103935471e-12 8.87407758943603 -1.12193520030729 1.84249294503327e-06 147.844421641097 48.9737140659834 3.01885255102162 0.00277818465404731 -151.881678800937 76.6368164682421 -1.98183700472312 0.0485039950202383 MTHFR other 0.0160757509454153 1 1 3.01885255102162 -1.98183700472312 4.4568760674078e-13 72.6959571127802 39.1675500896877 1.85602512657334 0.0645314064220544 -280.785453151431 62.9164028901979 -4.46283385974019 1.18558319791808e-05 DEAF1 other 5.55950720648448e-09 0.18220042585605 1 1.85602512657334 -4.46283385974019 7.41877842487834e-08 140.072138665041 31.2997844087183 4.47517902474832 1.122027418743e-05 -56.2275513457275 49.1235520641395 -1.14461493485472 0.253371230096498 MTX3 other 0.000716283056922004 1 0.114749744114846 4.47517902474832 -1.14461493485472 0.0397186461670757 -8.61964974625475 31.3766689464506 -0.274715259321045 0.783743547911346 -103.92243425136 50.4015987792661 -2.06188765373274 0.0401683183392426 TMEM80 other 1 1 1 -0.274715259321045 -2.06188765373274 3.40316568260059e-10 125.729375258915 23.2649042245446 5.40425071366808 1.41917619330172e-07 -124.269883846914 62.1828969378493 -1.99845761401433 0.0466586692229155 SIX5 other 3.77172852602623e-06 1 0.00166327449854961 5.40425071366808 -1.99845761401433 2.38057127980485e-19 161.744216504255 21.4810287834292 7.52963082610956 7.45155825130989e-13 -195.778866055588 57.82577779061 -3.38566766476559 0.000814388093076627 FBXO46 other 3.44897167018126e-15 1 1.05223454066747e-08 7.52963082610956 -3.38566766476559 6.82412303193953e-11 204.779839528373 50.1048074518757 4.08702976705495 5.75575508824753e-05 -264.484037336041 97.4932985296219 -2.7128432551257 0.00709638763675352 ZDHHC13 other 7.82112740690589e-07 1 0.553300736633235 4.08702976705495 -2.7128432551257 3.63822780347803e-25 105.065697050112 11.2075366936368 9.37455748949408 2.81287616971157e-18 -15.6720527920082 20.4336531455819 -0.766972634817223 0.443762978635075 SLC38A9 other 5.57813086829251e-21 1 4.25841323332634e-14 9.37455748949408 -0.766972634817223 0.00356172761265388 25.9650792981368 7.67764073178791 3.38190861036686 0.000828900812005493 18.6049394616961 26.8805358947677 0.69213424667317 0.489461322766202 ACER2 other 1 1 1 3.38190861036686 0.69213424667317 4.74177589532139e-11 219.407677957301 32.953581679274 6.65808287829594 1.59103416876297e-10 -41.3157632935801 65.5959744607714 -0.629852115670426 0.529334026867869 WDR73 essential 5.47722533668574e-07 1 2.11496172053662e-06 6.65808287829594 -0.629852115670426 0.000465299430110708 276.144737140748 88.7842364096829 3.11029016307033 0.00206845839411397 -313.211348777536 182.891551126313 -1.71255231227832 0.0879387659483053 POLE other 1 1 1 3.11029016307033 -1.71255231227832 0.361290070114753 26.737143849673 22.3252719359082 1.19761783535853 0.232120050122679 -14.4381378082406 50.9557636407994 -0.283346510318613 0.777129166355751 FAM109B other 1 1 1 1.19761783535853 -0.283346510318613 0.145795377378531 42.2970566790745 32.7250238361111 1.29249888070062 0.197285371925886 -35.8829711515445 58.4789467864227 -0.613604948847602 0.539991099303196 SCN4B other 1 1 1 1.29249888070062 -0.613604948847602 0.443169466293699 9.63964757354591 7.55651841752353 1.27567313952304 0.203155458081371 8.19970444768661 13.5559648508529 0.604877966113251 0.54576251284689 DSCAML1 other 1 1 1 1.27567313952304 0.604877966113251 6.27501987355712e-12 65.0017193820112 55.5204933070861 1.17076984569435 0.242723559749244 -425.533547387263 83.0851008137159 -5.12165891621588 5.76838071357072e-07 RHOG other 7.49362873300191e-08 0.0090580882345201 1 1.17076984569435 -5.12165891621588 0.000749900186082558 -92.459077024181 184.17447038977 -0.502018965106884 0.616060314412334 -933.116240918107 295.846821018874 -3.1540519438557 0.00179073881277506 EPS8L2 other 1 1 1 -0.502018965106884 -3.1540519438557 0.0835200252697293 131.132562797069 104.114334292589 1.25950536674951 0.208964455645439 -361.147618813745 264.782149704951 -1.36394246823729 0.173751826863046 ANO6 other 1 1 1 1.25950536674951 -1.36394246823729 5.57463365340508e-11 65.136234731105 15.122796778973 4.30715532868046 2.31171771229069e-05 -97.6652191680329 28.0836494742548 -3.47765411534444 0.000588733852975607 ZBTB34 other 6.41584587170391e-07 1 0.230408904384013 4.30715532868046 -3.47765411534444 0.61544492463333 3.41067074923203 3.48698223370774 0.978115321684741 0.328892857727872 3.45986902703996 5.48341125404751 0.630970187487963 0.528593764292931 LINC00982 other 1 1 1 0.978115321684741 0.630970187487963 8.44634387843606e-13 166.370698165116 23.2653385796401 7.15101126061885 9.55401169618476e-12 -13.6450606709251 52.896836034947 -0.257956083836665 0.796653871604486 FAM210A other 1.04388363993591e-08 1 1.31539633033072e-07 7.15101126061885 -0.257956083836665 1.96739916842313e-06 1674.11736299579 771.756084294024 2.16923118206086 0.030931349731935 -2568.6561829887 1239.7026778856 -2.07199373592523 0.0392083658081545 TALDO1 other 0.0171163727652812 1 1 2.16923118206086 -2.07199373592523 0.000103420072428361 221.128875133188 117.409424876706 1.88339969610957 0.0607169878918445 -818.142954995179 242.936589686404 -3.36772223587762 0.000867833995933858 ULK1 other 0.765308535969874 1 1 1.88339969610957 -3.36772223587762 0.00593245369434155 101.369561775517 47.3806219713801 2.13947300727181 0.0332874908844104 -108.869012431644 91.6453413410927 -1.18793831566896 0.235893976686567 RIMKLA other 1 1 1 2.13947300727181 -1.18793831566896 0.138839984448439 39.9351295871311 28.4015970822723 1.40608746302009 0.160869614233243 -69.8556716721159 85.7332636352581 -0.814802431519562 0.415917051955347 CLVS1 other 1 1 1 1.40608746302009 -0.814802431519562 0.131490845190326 4.90657120758787 12.7729473260313 0.384137746938663 0.701175384376442 -68.3789104638618 38.7445829991039 -1.76486376083705 0.0787047543970414 B3GNT8 other 1 1 1 0.384137746938663 -1.76486376083705 6.95520066087401e-07 131.8443558319 36.4643418246493 3.61570644729903 0.000357087588563737 -235.532299503226 75.4498444851602 -3.12170689164974 0.00199260619537005 PUS1 other 0.00627359099610836 1 1 3.61570644729903 -3.12170689164974 3.31295845873489e-14 86.7176100397054 40.9829887026554 2.11594158417457 0.0352618005394116 -392.402580857684 73.5189449305643 -5.33743487788478 1.99430467965448e-07 CHD9 other 4.28663694975707e-10 0.00314481904934716 1 2.11594158417457 -5.33743487788478 1.50451095358831e-09 105.353380228553 65.9949161567567 1.59638630312536 0.111563701493782 -389.076897613455 106.010274426547 -3.67018102460473 0.000291652619501553 GATD1 other 1.61072942691165e-05 1 1 1.59638630312536 -3.67018102460473 0.0562829234898645 48.3283148876682 23.6171608362515 2.04632196150715 0.0417152445909444 -5.48078990102473 48.456136678852 -0.113108272278271 0.910030678431199 TRIM72 other 1 1 1 2.04632196150715 -0.113108272278271 3.06476580250186e-11 634.630717677043 92.6359140487768 6.85080645226734 4.95736120153549e-11 52.3464812730349 174.395956625234 0.300158801190123 0.764286996659039 MAN1B1 other 3.56524205805042e-07 1 6.68946320535199e-07 6.85080645226734 0.300158801190123 0.0851337363271103 40.0178482759947 33.5596795064613 1.19243833268104 0.234136336925315 -43.2687268701163 56.1752023813852 -0.770246034475424 0.441827371831206 DEFB4B other 1 1 1 1.19243833268104 -0.770246034475424 0.73929204721676 -1.96781565232868 10.1064034773997 -0.194709785407754 0.84576497069397 6.87563219469132 14.7764268926029 0.46531087959656 0.642079801166198 KCNA3 other 1 1 1 -0.194709785407754 0.46531087959656 0.286096883254468 4.87505691758322 10.2177290666897 0.477117457877812 0.633664438893046 -13.3414495810069 15.2846506670075 -0.872865848992213 0.383511800758302 CLDN22 other 1 1 1 0.477117457877812 -0.872865848992213 0.0443412894524786 -28.0466931030792 25.5412002678002 -1.09809612739452 0.273130054099258 -91.4212710886919 37.3434208668249 -2.44812255992082 0.0149900584134152 KCNA2 other 1 1 1 -1.09809612739452 -2.44812255992082 1.05429637341259e-25 273.66185613993 27.1476318333173 10.0805056522122 1.63778264867421e-20 -54.3775550950001 67.3416513853554 -0.807487698569053 0.420091128364377 TOP3A essential 1.62214040013262e-21 1 2.51284991786084e-16 10.0805056522122 -0.807487698569053 0.0230528911602519 141.995724950305 51.3658446249869 2.7643996898521 0.00609403865160543 73.8390621916847 118.959483005383 0.620707658828202 0.535313655551144 CASKIN2 other 1 1 1 2.7643996898521 0.620707658828202 0.0012347349692172 317.747003051921 85.9986533911908 3.69479044754983 0.000266577731942092 52.669904782425 457.526836726178 0.115118722126342 0.908436903808219 ZBTB38 other 1 1 1 3.69479044754983 0.115118722126342 0.706329213804827 -0.550361771854695 2.27776615906637 -0.241623473798681 0.809254659332566 -7.10520222411149 8.51992749277207 -0.833951020139459 0.405043053175422 C8orf31 other 1 1 1 -0.241623473798681 -0.833951020139459 0.988753626746801 0.516871286737851 4.14955748384065 0.124560579953566 0.900963105011128 -0.0962629285672208 7.75362612681741 -0.0124152141195301 0.990103414677551 RPL13AP3 other 1 1 1 0.124560579953566 -0.0124152141195301 1.96103897006258e-05 62.0400624130224 18.9872201464828 3.26746421721532 0.00122400940062316 -100.927339434066 45.3481226135172 -2.22561229919541 0.026857003254438 CCDC71 other 0.156642009339931 1 1 3.26746421721532 -2.22561229919541 0.719919010386086 -3.64863881183152 5.51490187258204 -0.661596325035472 0.508794172059905 -7.43446895667221 11.2166406542113 -0.662807090452784 0.508019529577282 LRRN4CL other 1 1 1 -0.661596325035472 -0.662807090452784 9.23899469873566e-25 182.772336668628 17.978863312332 10.1659561838518 9.3359086618518e-21 -152.119047568088 54.1600456263431 -2.80869496709025 0.00533892824651718 TIMM22 essential 1.41227272964873e-20 1 1.43446236589353e-16 10.1659561838518 -2.80869496709025 9.73626568104116e-07 124.370026684093 28.8866138135142 4.3054553741397 2.32839610890936e-05 -181.139642462859 89.5876189274274 -2.02192718850576 0.0441627631014786 HIC1 other 0.00867501272180767 1 0.231954820369551 4.3054553741397 -2.02192718850576 0.0114721759870337 26.1901634202942 37.1032479116893 0.705872528535247 0.480873760734468 -183.096377910729 76.5590580791913 -2.39157040988328 0.0174586361968451 PPFIA3 other 1 1 1 0.705872528535247 -2.39157040988328 2.3891761802576e-31 461.969518964827 34.0181814076925 13.5800768838384 2.41121800761038e-32 581.112294450331 363.094876248829 1.60044201244 0.110674297164829 MAGEF1 other 3.75267902633061e-27 1 3.81237679183278e-28 13.5800768838384 1.60044201244 0.0481270030891336 14.2522331488353 11.2499438884047 1.26687148755694 0.206292957675752 -19.2520880151672 16.4928485964315 -1.16729914196464 0.244119430727429 UMODL1 other 1 1 1 1.26687148755694 -1.16729914196464 0.0993807881267641 -52.5540920116708 39.8887527790186 -1.31751655166602 0.188807786347225 -353.94501723361 187.179676698834 -1.89093721859075 0.0597275834168219 SAMD9L other 1 1 1 -1.31751655166602 -1.89093721859075 7.0014444083158e-06 390.926027397261 106.027669021177 3.68701897350191 0.000274441734613041 -782.913698630135 348.819845350596 -2.24446432468094 0.0256156654753036 ZFAS1 other 0.0580559770337546 1 1 3.68701897350191 -2.24446432468094 9.09383565819062e-07 321.20318760188 75.5481552644233 4.25163508596139 2.94032333077788e-05 -322.716287944071 170.112159479314 -1.89707948527521 0.0589005137293496 PAWR other 0.00812170462633005 1 0.290503945080855 4.25163508596139 -1.89707948527521 8.43460684055456e-09 493.401467188703 94.2989166843673 5.23231320716221 3.43200025130328e-07 -244.39230723841 203.729988514826 -1.199589265282 0.231382578230079 TGIF1 other 8.63366356199164e-05 1 0.0039279242876166 5.23231320716221 -1.199589265282 2.96000325440846e-15 57.6686107705156 11.4553967116028 5.03418713662747 8.74297998944437e-07 -108.341965516119 28.4159346410085 -3.81271870465824 0.000170077619110884 MIEF2 other 3.93917233096678e-11 1 0.00973618251624525 5.03418713662747 -3.81271870465824 1.08233034719582e-06 -0.933291899730693 11.4386126942367 -0.0815913541858911 0.935031682066913 -75.5897037497411 17.7201531855839 -4.26574775951917 2.75236648325157e-05 NAP1L5 other 0.00961109348309884 0.418745036761893 1 -0.0815913541858911 -4.26574775951917 0.000166915738907313 8.03877976685967 2.07275834558125 3.87830051872517 0.000134670203110286 -13.9266742893282 13.1470646190005 -1.05929914341495 0.290490048663817 NIM1K other 1 1 1 3.87830051872517 -1.05929914341495 0.0781797307657348 -35.0861869121739 17.6106015724733 -1.99233324130257 0.0473642748044195 -68.5861682838788 35.4926120860156 -1.93240689407874 0.0543790392877664 CD19 other 1 1 1 -1.99233324130257 -1.93240689407874 0.746173798954687 3.95397405470199 7.43188713861055 0.532028269665195 0.595143912394104 -10.4192577853293 27.0498299694261 -0.385187551903505 0.700401731847895 ERICH5 other 1 1 1 0.532028269665195 -0.385187551903505 4.81341319455927e-06 165.540015902174 42.537445721658 3.8916303763366 0.000125195307718813 -198.795858123359 116.353541666732 -1.70855012469465 0.0886709065267495 NR2C2 other 0.0404711781398543 1 1 3.8916303763366 -1.70855012469465 0.640610023937042 -4.10368579141128 13.282189825784 -0.30896153761069 0.757586438429461 26.406451345202 36.8589272767539 0.716419421187441 0.474344809840103 GPR4 other 1 1 1 -0.30896153761069 0.716419421187441 0.00490735347195086 6.93239400510608 6.08347620572709 1.13954485407205 0.255478491148792 -26.4972370290452 11.9026883116644 -2.22615566628578 0.0268231612222969 ACOT4 other 1 1 1 1.13954485407205 -2.22615566628578 0.255702436358908 798.067997517116 578.261963392809 1.38011497909122 0.168697139060653 1539.98474470376 1076.88776168417 1.43003272903328 0.153868065299466 CAVIN1 other 1 1 1 1.38011497909122 1.43003272903328 1.00328694317212e-10 316.245746571863 51.5400769892283 6.13591917291776 2.96611463155943e-09 -169.759769482534 122.960610252001 -1.3806028543175 0.168530386591847 ARIH2 other 1.1413392265526e-06 1 3.76488930183839e-05 6.13591917291776 -1.3806028543175 0.166215539859155 -8.89886028841677 16.3185570424725 -0.545321517414537 0.585982601818127 -115.068315103514 60.7008889576356 -1.89566111929305 0.0590726879739786 ZBED2 other 1 1 1 -0.545321517414537 -1.89566111929305 0.0927805850779528 -44.0024716537613 52.8421063508334 -0.83271607989312 0.405732751204851 -201.398641768906 94.5397744038817 -2.13030592720176 0.0340404446268881 IRX3 other 1 1 1 -0.83271607989312 -2.13030592720176 0.729979898434799 -43.3071204166459 87.4278340105045 -0.495347058597409 0.620755094602399 -158.723560893507 209.582833925712 -0.757330922196459 0.44950718665929 RPRM other 1 1 1 -0.495347058597409 -0.757330922196459 1.19616656457474e-07 106.841549732868 71.3466587804636 1.49749899377382 0.135423002208028 -360.119068018351 114.60699273818 -3.14220851114247 0.00186210002709575 SLC25A22 other 0.00114006635269618 1 1 1.49749899377382 -3.14220851114247 5.96991249905248e-07 83.7491886342562 33.0193050134238 2.53637042330868 0.0117776266502969 -197.945317674527 66.5474929614621 -2.9744969925337 0.0032063126681011 RABEP2 other 0.00541351665414079 1 1 2.53637042330868 -2.9744969925337 0.0341099853533701 -3.21439181253717 12.8579338353507 -0.2499928723929 0.802782262510836 -40.1573596633672 18.773544117283 -2.13903988572931 0.0333261897182858 NHLH2 other 1 1 1 -0.2499928723929 -2.13903988572931 1.50898532848381e-08 149.890005783237 39.1464802200183 3.82895230786515 0.000159657959335441 -163.781627278579 65.3268711999931 -2.50710962074357 0.0127535364394882 ATOX1 other 0.000151939732725035 1 1 3.82895230786515 -2.50710962074357 5.7971384626474e-29 1348.91167720024 104.165436052112 12.9497050876397 4.53563779901987e-30 77.6754765806568 1081.85616844771 0.0717983396000866 0.942816347850353 TBL1XR1 other 9.04411571557621e-25 1 7.15406150039404e-26 12.9497050876397 0.0717983396000866 0.864762974685307 -19.5004062820229 44.7058691473144 -0.43619342726042 0.663042402349332 -70.1299052911461 182.035743096224 -0.385253489772475 0.700350711786031 SAMD12 other 1 1 1 -0.43619342726042 -0.385253489772475 0.817690260118824 -11.0426674541391 113.232164448436 -0.0975223560189716 0.922383668496079 312.06726953817 522.228248267944 0.597568727033042 0.550626727117415 CD163 other 1 1 1 -0.0975223560189716 0.597568727033042 4.41646390884439e-09 189.379564045693 75.8237614432049 2.49762818991176 0.0130982934263187 -473.823126088099 121.158077287274 -3.91078446189462 0.00011644773034291 C18orf32 other 4.59312246519816e-05 1 1 2.49762818991176 -3.91078446189462 0.000371990572876963 80.5504691550335 41.0566266243537 1.96193588655072 0.0507895583280043 -84.4431841692127 65.950902114002 -1.28039467941235 0.20149716344721 PIDD1 other 1 1 1 1.96193588655072 -1.28039467941235 0.394634792196282 -1.66533938646588 1.67801908075503 -0.992443653093953 0.3218631965136 -4.75613293009734 3.66948755415527 -1.29613000722991 0.196029372735328 ZNF491 other 1 1 1 -0.992443653093953 -1.29613000722991 1.85333060419005e-06 1964.92632866409 773.788780792292 2.53935748028316 0.0116629083468761 -2107.89973104212 1242.9678796035 -1.6958601791983 0.0910565713997375 RPLP2 essential 0.0161628961991415 1 1 2.53935748028316 -1.6958601791983 3.37778856443496e-05 1622.41259352734 386.855949508434 4.19384164981537 3.71862295444611e-05 426.520104237794 632.940892335927 0.673870355672048 0.500968093271508 JUN og 0.263231062826417 1 0.363704326151768 4.19384164981537 0.673870355672048 1.49391081838006e-11 204.502430390419 42.1303734665319 4.85403792000264 2.05309397267417e-06 -110.70528665312 64.7416561948208 -1.70995450471618 0.0884273757105561 CSTF2T other 1.76147024595192e-07 1 0.0222658041336514 4.85403792000264 -1.70995450471618 0.0264378148602162 183.974021901443 69.7385885196225 2.63805198537504 0.00881867641803899 185.727605774016 196.488243592037 0.945235207861276 0.345377709893611 PGBD5 other 1 1 1 2.63805198537504 0.945235207861276 0.648652071352845 -18.0503199153288 19.4143010709047 -0.929743483909392 0.353325286741753 -12.9171513626378 49.0462736416955 -0.263366621020044 0.79246668454391 C12orf54 other 1 1 1 -0.929743483909392 -0.263366621020044 0.000126652960810574 194.527612214403 46.9309721965085 4.14497299139427 4.5578665779985e-05 -141.630956107619 157.181719859296 -0.90106506172857 0.368359741606524 GBA other 0.926593061290157 1 0.441930743402735 4.14497299139427 -0.90106506172857 0.000415449836820713 2.49150222160353 4.83091971638806 0.515740763223935 0.606454430363321 -20.2010881796772 6.74293746874428 -2.99588840521151 0.0029888370857703 CASC2 other 1 1 1 0.515740763223935 -2.99588840521151 8.23473863042299e-23 324.86319248318 30.4258608651745 10.6772062727408 1.97168665610105e-22 -137.194802734431 116.152849508914 -1.18115744309745 0.238579557272746 ACAD9 other 1.24122215376366e-18 1 3.0517766063132e-18 10.6772062727408 -1.18115744309745 1.17966073802829e-13 197.404697762439 32.5839110800496 6.05834877456763 4.82272387154128e-09 -270.790575253257 93.5702781593428 -2.89398065903066 0.00412783186426609 IL17RA other 1.50088235699339e-09 1 6.06988026472186e-05 6.05834877456763 -2.89398065903066 4.91346512209158e-06 -56.6780665485335 113.217346205567 -0.500612922384033 0.617048392112911 -713.154309903525 176.326565393572 -4.0445085986432 6.83492918592878e-05 PNPLA2 other 0.0412976743511798 1 1 -0.500612922384033 -4.0445085986432 1.53972157900283e-10 241.555747371941 102.092953645875 2.36603740753562 0.0186808949651858 -679.742348909773 159.760783932338 -4.25475096064661 2.88225499106991e-05 AGTRAP other 1.73526621953619e-06 0.438333339041912 1 2.36603740753562 -4.25475096064661 0.518980507425997 12.0385874704844 11.9968165621902 1.00348183270767 0.316523593504337 40.6313406659093 55.2845884386554 0.734948777108007 0.463006201245012 CD163L1 other 1 1 1 1.00348183270767 0.734948777108007 0.00011827229622796 109.153259090844 25.5037270976529 4.27989441201672 2.59951656438948e-05 59.7719428761766 82.6429383479722 0.723255296471961 0.470149136928963 SRRM3 other 0.868236926609452 1 0.258002019015656 4.27989441201672 0.723255296471961 1.09784702499939e-05 82.8078561353646 21.8430487232854 3.79103929970585 0.000185653058438608 -134.112544260225 70.5821849411022 -1.90009057345187 0.0585025398115654 THAP5 other 0.0895843172399506 1 1 3.79103929970585 -1.90009057345187 0.456807510111941 -30.2306556408744 49.7300073292659 -0.607895660274391 0.543763896120381 -94.3800354400476 77.4503349817564 -1.21858782744166 0.224056522997316 CRACR2B other 1 1 1 -0.607895660274391 -1.21858782744166 1.20479928049282e-05 -0.692863247521932 1.84300270089615 -0.375942611036343 0.707259210043013 -11.5965478406032 2.6372759753061 -4.39716887773084 1.58717653617869e-05 DNAJC28 other 0.0979983734752864 0.243171317107937 1 -0.375942611036343 -4.39716887773084 1.31348564936028e-10 58.8102345098506 8.37940617120898 7.01842508982536 1.9046208915318e-11 66.8090691656826 87.0738692581658 0.767268868776234 0.44360991811422 NAALADL2 other 1.48515822373167e-06 1 2.60037890320837e-07 7.01842508982536 0.767268868776234 0.126718232864697 -181.321013781018 425.216069704144 -0.426420887402438 0.67013846238698 -1151.50291180213 658.941770617181 -1.74750328959052 0.0816785651206708 CD151 other 1 1 1 -0.426420887402438 -1.74750328959052 0.00845159247931613 153.396520823418 116.878797790173 1.31244095356631 0.190477779546888 -211.109793200282 181.122792506526 -1.16556171798575 0.244812768731559 POLR2L essential 1 1 1 1.31244095356631 -1.16556171798575 0.428174892938331 66.8481463239294 65.7966300970197 1.01598130824267 0.310564973432771 -88.4385534925454 158.526852256619 -0.557877433593291 0.577399059524343 FAM20C other 1 1 1 1.01598130824267 -0.557877433593291 0.00324974290791694 65.5258748432686 20.8505207448032 3.14264932014229 0.00186080974599901 -53.0356518299641 78.155212301848 -0.678593919304215 0.497976405282467 NECTIN3 other 1 1 1 3.14264932014229 -0.678593919304215 6.4047837599351e-05 9.01272031638239 2.0195258744844 4.46279021737387 1.22631805069511e-05 14.5807684508372 12.8094223951343 1.13828461589148 0.256095670928655 ANXA2R other 0.485802848191077 1 0.125059914809887 4.46279021737387 1.13828461589148 1.13944700447842e-20 1031.80762052539 141.399906070048 7.29708844370975 3.23394550160193e-12 -1071.59845050402 350.752626930981 -3.05514019917771 0.00247295395387292 FLII other 1.67977277400208e-16 1 4.50456268918133e-08 7.29708844370975 -3.05514019917771 3.30369490272386e-20 532.425855712006 51.8041277967034 10.2776724241246 4.62474012526622e-21 132.596361625504 196.479066421552 0.674862538999521 0.500353689691915 SOX12 other 4.84024340198072e-16 1 7.11285031265944e-17 10.2776724241246 0.674862538999521 2.32303491950264e-06 760.398889644444 183.669843407461 4.14003124049898 4.63202834313451e-05 -257.640121841028 302.936688512341 -0.850475137581535 0.395806267592058 HNRNPA0 other 0.0200570834949858 1 0.448519304465715 4.14003124049898 -0.850475137581535 0.0748841027215922 7.81860648356595 7.45882973453574 1.04823501297588 0.295471235593655 -11.5168505177848 11.6849732544814 -0.98561205635348 0.325209189020558 MYOZ1 other 1 1 1 1.04823501297588 -0.98561205635348 0.284176450299215 7.94914891939277 5.12144457312064 1.55213022534951 0.121789542394232 8.53839912735049 19.1467284181825 0.445945591375395 0.655990017272388 KCNJ10 other 1 1 1 1.55213022534951 0.445945591375395 8.33115747428166e-14 202.296260052485 80.5167245274667 2.51247503223353 0.0125677822947345 -498.126140353847 124.143497035577 -4.01250288777586 7.77144365848767e-05 CHID1 other 1.06488854836268e-09 1 1 2.51247503223353 -4.01250288777586 0.0395915062417918 12.2677180975053 12.3255953762779 0.995304301576869 0.320469648450622 -34.8763693949866 21.5025702729377 -1.62196281431903 0.105965584503509 PCDHB9 other 1 1 1 0.995304301576869 -1.62196281431903 0.00371831679976702 17.5685658940618 6.19924871373153 2.83398306881073 0.00494037001533312 -9.13752143032071 16.1942532562667 -0.564244691355852 0.573050878669407 ZNF620 other 1 1 1 2.83398306881073 -0.564244691355852 5.13700274260291e-07 126.931789083677 34.021109565837 3.73097146752491 0.000232188926046339 -89.0265043739016 53.4661837127644 -1.6650992869096 0.0970443131944402 ZNF518A other 0.00468597390180237 1 1 3.73097146752491 -1.6650992869096 2.24320528499763e-26 176.96391905529 17.6125039662312 10.0476297631834 2.18799268326039e-20 -49.1796362963409 33.0106285662348 -1.48981217360535 0.137440828668881 SVBP other 3.46036847263735e-22 1 3.35463038197482e-16 10.0476297631834 -1.48981217360535 5.03576098638064e-07 19.7691937746308 5.27628188515419 3.74680394356017 0.000218540424307023 -30.9681361743818 13.7831935844702 -2.24680412304985 0.0254517525128908 ZNF619 other 0.00459916050886144 1 1 3.74680394356017 -2.24680412304985 0.221421902192226 -15.2708188460731 11.281850069433 -1.35357399292585 0.17699604725003 -42.3111079669011 28.4801030343981 -1.48563746120574 0.138533121372783 CCDC184 other 1 1 1 -1.35357399292585 -1.48563746120574 1.02987963102164e-09 265.300616522811 59.3429978256702 4.47063050812119 1.1460309998532e-05 -218.349969734335 97.7430257912011 -2.23391866546852 0.0263013587780309 AP3S1 other 1.11093115798304e-05 1 0.117147288804994 4.47063050812119 -2.23391866546852 7.51694541198411e-12 671.577589996176 92.3390976659673 7.27294945447246 3.78586128689947e-12 -13.0305669800575 210.257880123097 -0.0619742145808219 0.950629048904153 GRB2 essential 8.95568876383786e-08 1 5.2649972916911e-08 7.27294945447246 -0.0619742145808219 3.15774459080216e-09 207.733425918828 32.405913348045 6.41035553257628 6.54793061715527e-10 -25.6901166487059 86.7603487360007 -0.296104349774772 0.767380566325108 ZBTB41 other 3.31405294804687e-05 1 8.51361938842528e-06 6.41035553257628 -0.296104349774772 0.000120399583449738 315.133308897581 91.2664515707802 3.45289318773596 0.000643328678466367 -326.921074295366 209.152455148283 -1.56307548034083 0.119201812513526 UBE2N essential 0.882408547103133 1 1 3.45289318773596 -1.56307548034083 4.60930418290497e-11 222.96759668366 33.6968026700915 6.61687694427936 1.94286024497052e-10 -22.9087594623824 80.3055465852456 -0.285269952531416 0.775654431645851 ARL6IP6 other 5.32605098334669e-07 1 2.57409553856144e-06 6.61687694427936 -0.285269952531416 0.0683124303092375 29.0130761874491 21.7893211306191 1.33152731163702 0.184126290613669 83.5427478895938 36.3093488971733 2.30086053391328 0.0221532986513246 ZNF354C other 1 1 1 1.33152731163702 2.30086053391328 0.328044320244797 23.2592358800301 15.5568353767016 1.49511358298898 0.136052646564774 15.0273880136062 29.2872285596774 0.513103791401277 0.60829828276383 MAMDC4 other 1 1 1 1.49511358298898 0.513103791401277 1.99076894403706e-18 104.921449630856 18.358335165803 5.71519414387303 2.98503951168392e-08 -97.7455593953531 29.914537777552 -3.26749355521387 0.00123050843117699 CENPBD1 other 2.84301712897932e-14 1 0.00036208529276726 5.71519414387303 -3.26749355521387 3.12571792099758e-12 163.220111075309 73.9467080838629 2.20726676419728 0.0281335932444978 -455.005451409289 118.346546752788 -3.84468718263275 0.000150482411802043 BET1L other 3.77774267931767e-08 1 1 2.20726676419728 -3.84468718263275 5.19092822556658e-08 125.970988729524 21.253430527977 5.92708967917918 9.27708940780059e-09 -32.7681269156744 72.9732282106468 -0.449043131558946 0.653756795324566 RPS27 essential 0.00050601168342823 1 0.000115379160964816 5.92708967917918 -0.449043131558946 2.53367024230297e-11 245.121751399882 48.9590561678148 5.00666823640734 1.0071604421981e-06 -283.382052778958 95.3438084047576 -2.97221243330173 0.00322634352075363 IMP3 essential 2.95729990681603e-07 1 0.0111684021435347 5.00666823640734 -2.97221243330173 6.80679946664946e-07 62.8558261378994 19.3792713786868 3.24345662484647 0.00132886662924803 -153.891226341613 49.3407465940988 -3.11894806958633 0.00201069674806769 ASB8 other 0.00614449787854447 1 1 3.24345662484647 -3.11894806958633 0.201153420273479 9.04852929028247 47.8105712311972 0.189257920524032 0.850036646434875 -153.719831607851 100.893024452857 -1.52359226459385 0.128812103942216 ODF3B other 1 1 1 0.189257920524032 -1.52359226459385 0.00294508330864138 18.5368181039368 6.5387512989938 2.83491713575179 0.00493155209650665 -18.5778076522611 18.701013611594 -0.993411803130472 0.321402058462937 DPY19L2 other 1 1 1 2.83491713575179 -0.993411803130472 2.75779743131245e-05 51.9678012557297 14.2624545894022 3.6436786480179 0.000322041539255673 -62.469645840753 41.2893968194781 -1.51297065718536 0.131452417546864 LRRC75B other 0.216864682594014 1 1 3.6436786480179 -1.51297065718536 3.60580200917588e-17 261.313923377934 38.8560676505362 6.72517676590796 1.03653622609245e-10 -154.257184659742 68.3407396960939 -2.25717756854422 0.0247933719379223 DMAP1 essential 5.03153612360402e-13 1 1.38439778356908e-06 6.72517676590796 -2.25717756854422 0.197959036092025 15.0791669805686 17.2967783448568 0.871790496468521 0.384114812901412 -78.4288563535438 62.1441949047625 -1.26204638218804 0.208045906702413 ADAMTSL1 other 1 1 1 0.871790496468521 -1.26204638218804 2.32227307933054e-12 1003.76880824864 160.379906970878 6.25869429161663 1.49745962846637e-09 -860.009045671144 383.043311761839 -2.24520052762562 0.0255558053773579 IMPDH2 essential 2.82225847331041e-08 1 1.92288790891367e-05 6.25869429161663 -2.24520052762562 0.0521164338536897 -217.299978325265 141.472103848635 -1.5359917072963 0.125698544403615 -848.902969438623 367.706533797362 -2.30864260330615 0.0217106331414583 ALS2CL other 1 1 1 -1.5359917072963 -2.30864260330615 6.47123283714908e-06 159.637441555351 32.2812565516436 4.945205317518 1.37198433413117e-06 -102.071838973066 218.595256996253 -0.466944435920745 0.640933713772493 MLF1 other 0.0537888873423831 1 0.0150698759260968 4.945205317518 -0.466944435920745 8.74764616607513e-05 209.000200312065 50.0868601392574 4.17275508448679 4.04868025957066e-05 1.64536330282842 119.624940217585 0.0137543500530548 0.98903600859386 NDUFAF3 essential 0.652924309835847 1 0.394584378097757 4.17275508448679 0.0137543500530548 1.34386777671028e-19 234.331168073333 23.885398241609 9.81064521943459 1.33141493299936e-19 22.9169809786018 55.2312968509296 0.414927446669507 0.678528220034097 C2orf69 other 1.9533118134484e-15 1 2.03453515911632e-15 9.81064521943459 0.414927446669507 0.000301428729942618 47.731752035008 11.6800591176845 4.08660192162369 5.76575678024611e-05 31.8447344198062 44.8023945189522 0.710781974082552 0.477828374627759 GRAMD1C other 1 1 0.554089226581651 4.08660192162369 0.710781974082552 1.36105489768551e-15 184.704475487245 87.9732725421132 2.09955217249451 0.0366862480270586 -900.250659691683 157.738336927054 -5.70724072048512 2.9875679209692e-08 STAP2 other 1.8272162001428e-11 0.000473798396586505 1 2.09955217249451 -5.70724072048512 5.90456315652692e-12 12.1802561705438 2.27743791352677 5.34822754034242 1.89465768972666e-07 -12.6351547327406 5.2407380460426 -2.41094949255891 0.016579289437731 TSSK6 other 7.05654342836533e-08 1 0.00220291849584518 5.34822754034242 -2.41094949255891 3.27480136336882e-05 74.2515061254708 16.6252925763262 4.46617740918449 1.19008899310717e-05 -60.3746555824807 56.6736900747139 -1.06530306219496 0.287730906860602 BOLA1 other 0.255565498397303 1 0.121460482636518 4.46617740918449 -1.06530306219496 5.48795936479639e-16 329.282272620261 40.9001922031415 8.05087347719038 2.66702587818355e-14 42.9063781268604 72.0279282471498 0.595690854520146 0.551882621667336 DDX10 other 7.44057530679095e-12 1 3.86105336384633e-10 8.05087347719038 0.595690854520146 0.132367853860817 -0.730270445616525 1.51414807586838 -0.482297905505515 0.62998800132424 -5.32928045366622 2.78301580016413 -1.9149300026798 0.0565658779544751 GOLGA8O other 1 1 1 -0.482297905505515 -1.9149300026798 2.46561963733587e-12 48.9887965943423 7.01816772228167 6.98028296457065 2.31336060108892e-11 -10.7135433148387 22.526204339141 -0.475603574998345 0.63474425213591 PPP1R42 other 2.99326223972574e-08 1 3.15010313050278e-07 6.98028296457065 -0.475603574998345 1.05390406423883e-10 268.548004081584 48.0734525410983 5.58620173685259 5.69616222495967e-08 -182.947753820878 104.615556603273 -1.74876241890734 0.0814769838179762 NDUFV2 other 1.19723501697531e-06 1 0.000682628081039167 5.58620173685259 -1.74876241890734 3.92298578563334e-10 252.733711466285 48.7272188131128 5.18670504129557 4.17660924042244e-07 -301.294015940622 116.377641187357 -2.5889338610633 0.0101434449727073 DALRD3 other 4.33764538317478e-06 1 0.00475131067190457 5.18670504129557 -2.5889338610633 0.205226538949335 13.8016418758741 7.7491775712492 1.78104602055843 0.076020829450026 10.344529697849 16.1385415804966 0.640982931837553 0.522073456163448 ZNF114 other 1 1 1 1.78104602055843 0.640982931837553 2.77614015137941e-10 159.643603140246 57.7002545491578 2.76677467695117 0.00605105352364607 -247.349251918549 83.8040913448305 -2.95151761625546 0.00343892771524686 ZNF518B other 3.09095444454583e-06 1 1 2.76677467695117 -2.95151761625546 0.00719551688219688 14.6985221869299 17.4629551702126 0.841697298290145 0.400696813523438 -67.0415001286803 29.1130752081287 -2.30279692713333 0.0220451996493081 SPINK6 other 1 1 1 0.841697298290145 -2.30279692713333 0.412428773269595 -6.10490305573161 6.98198868321686 -0.874378824246226 0.382686199983474 -14.2030748488233 10.8644837606041 -1.30729403824279 0.192220939079024 ZNF366 other 1 1 1 -0.874378824246226 -1.30729403824279 7.86901602279084e-13 105.598729946961 20.4459731540778 5.16476907952408 4.68025938281326e-07 -30.0354798087154 29.4368808502059 -1.02033499953869 0.308482973152674 LCORL other 9.738385146546e-09 1 0.0053032019066657 5.16476907952408 -1.02033499953869 6.62645328891154e-05 131.848867131462 60.317316834112 2.18592062863274 0.0297493626995796 -199.40385456264 91.221414297212 -2.18593250388505 0.0297484831923597 PARD6G other 0.501357455839047 1 1 2.18592062863274 -2.18593250388505 3.57169701972769e-06 136.526261756524 62.0500624489095 2.20025986063973 0.028654896197834 -365.879615677573 125.056420551503 -2.92571636117547 0.00373557382609815 SH2B1 other 0.030352895564317 1 1 2.20025986063973 -2.92571636117547 0.88815700131517 -2.50706040304118 6.64509129205383 -0.377280054231777 0.706260774407242 1.91990156037108 12.2039490958642 0.157318057072339 0.875111336082826 ZC3H12D other 1 1 1 -0.377280054231777 0.157318057072339 5.53798508242533e-05 2.65329456822567 1.9401645602348 1.3675616092609 0.172578252809326 -14.4241630606386 4.30337519210618 -3.35182558264902 0.000916660563698146 VN1R1 other 0.422326742385756 1 1 1.3675616092609 -3.35182558264902 6.51821052081358e-09 381.462474678988 73.760760531612 5.17161797044518 4.53740777812812e-07 -87.1147857967956 129.863649189053 -0.67081732525455 0.502912463094958 KDELC2 other 6.71766776275048e-05 1 0.00514723538350854 5.17161797044518 -0.67081732525455 0.000963549303424609 2276.32610720972 629.11230647213 3.61831438328501 0.000354351613025665 -212.338047858285 2382.11067829663 -0.0891386155114007 0.929038324873301 PLEC other 1 1 1 3.61831438328501 -0.0891386155114007 0.0439918387489272 33.8930165284378 19.235869946704 1.7619695195665 0.0792060521050867 -46.0780013109466 52.3662574348976 -0.879917786147527 0.379686342870457 RNF212 other 1 1 1 1.7619695195665 -0.879917786147527 0.00887412848746817 -2.97747937414573 5.07050128064127 -0.587215979120937 0.557556752572483 -30.7195117734167 10.4639763017788 -2.93573980745682 0.00361845639142551 PRSS36 other 1 1 1 -0.587215979120937 -2.93573980745682 1.63346534858975e-09 31.115252072131 7.07340437669 4.39890757195638 1.5631211220586e-05 -41.9652505867325 15.7638028110292 -2.66212734895233 0.00822714931253797 ZNF543 other 1.74454099229385e-05 1 0.157969020595242 4.39890757195638 -2.66212734895233 0.0614474058763706 19.6260145907816 10.0737911279792 1.9482252849448 0.0524278784783908 -14.4674123103682 23.3460334333725 -0.619694662549718 0.535983368832758 TMEM151B other 1 1 1 1.9482252849448 -0.619694662549718 9.00166552321528e-05 146.353112133688 91.3683694673882 1.60179187816113 0.110370912148127 -684.223283482685 230.380452783088 -2.96997108572795 0.0032461291696408 GALNT11 other 0.671074164755699 1 1 1.60179187816113 -2.96997108572795 3.01129536594215e-08 797.213174208242 184.632728396742 4.31783238611508 2.20692932627637e-05 -1179.98705351494 440.967531908806 -2.67590461458049 0.00790326140725288 WDR6 other 0.00029826880599657 1 0.220229477469119 4.31783238611508 -2.67590461458049 3.38204848935823e-05 158.489406004171 34.7193707559623 4.56486977019748 7.62194113604179e-06 27.2025681754521 113.595920915425 0.23946782557188 0.810925881618999 GEN1 other 0.263529218290793 1 0.078978554051665 4.56486977019748 0.23946782557188 0.000108863759736518 5.52962541869777 2.82936276531043 1.95437131162327 0.0516817965402521 -9.67854565507474 4.69242361475825 -2.0625899214714 0.0401009695382946 TMPRSS9 other 0.803196819336028 1 1 1.95437131162327 -2.0625899214714 2.10267074438187e-10 14.9985349057137 2.56926046311262 5.83768563796884 1.50913141155812e-08 -7.78933554354186 6.49061247360165 -1.20009252982247 0.231151458909293 AQP11 other 2.35625283615432e-06 1 0.000185834442019267 5.83768563796884 -1.20009252982247 5.20216706764603e-29 216.332893990759 22.8120891894044 9.4832565397491 1.26408032196298e-18 -116.822204997044 55.8329170609375 -2.09235359975086 0.0373303986026461 TMEM11 other 8.12058279259546e-25 1 1.919000336772e-14 9.4832565397491 -2.09235359975086 0.00151575325044953 32.6805288161981 11.1946389287966 2.91930173220077 0.00380064120233025 -12.6515810019335 18.6545532193001 -0.678203377652815 0.49821719034489 ZNF354B other 1 1 1 2.91930173220077 -0.678203377652815 0.81200348338259 6.57779520166991 15.3733061157789 0.427871217299094 0.669087227591453 -1.90546125383839 22.6050740449427 -0.0842935196783699 0.932885762113772 SHISA3 other 1 1 1 0.427871217299094 -0.0842935196783699 0.0764759558879676 1834.96213674126 1433.64352713137 1.27992914697066 0.201672765782016 -1931.73326924794 2467.50841083919 -0.782867957313653 0.434393306194354 CALML3 other 1 1 1 1.27992914697066 -0.782867957313653 0.436218976937541 -53.8218742697774 221.131130737227 -0.243393474678763 0.807886103278945 -445.547212000431 380.598743457717 -1.17064814232612 0.242776244798225 CALML5 other 1 1 1 -0.243393474678763 -1.17064814232612 1.55155917965781e-08 143.190911157495 26.7362445237843 5.35568527696975 1.83020009169066e-07 -116.975526462626 64.2024529754303 -1.82197908399842 0.0695685323561033 ZFAND2A other 0.000156117884657169 1 0.00212998686670959 5.35568527696975 -1.82197908399842 4.3348404538921e-06 68.9400605816508 24.990861455584 2.75861081076286 0.00620295653973858 -109.886378623839 43.4856591020409 -2.52695672304255 0.0120792282929881 PLEKHM3 other 0.0366337366758421 1 1 2.75861081076286 -2.52695672304255 3.08592155969346e-12 27.0507337344703 4.45656240901594 6.0698653472786 4.26732727734227e-09 -28.372768855605 12.3394302947777 -2.2993580884859 0.022239665100078 ZNF223 other 3.73057057351342e-08 1 5.3823798949118e-05 6.0698653472786 -2.2993580884859 2.68029864140652e-10 167.102562756013 25.5289006277354 6.54562314267728 2.9375481592668e-10 -52.2823018017596 67.6275601361518 -0.773091646312566 0.440139448932094 FAM220A other 2.98692480598342e-06 1 3.86522586796326e-06 6.54562314267728 -0.773091646312566 0.152655547001777 9.2749958784066 16.4505203962745 0.563811700480132 0.573346836990693 -65.2419660634344 41.9639898632314 -1.55471313085506 0.121177146701326 DNAJC22 other 1 1 1 0.563811700480132 -1.55471313085506 0.896968709094057 -5.39920959469667 16.3219096884367 -0.330795213168086 0.741052920847061 -15.0116452394261 36.6336844745552 -0.409777106909703 0.682290816359859 CEP295NL other 1 1 1 -0.330795213168086 -0.409777106909703 1.28918430649469e-08 73.5420836318876 13.937614886321 5.27651856014943 2.7332292808931e-07 -26.6374334082214 24.3594967954461 -1.09351328690833 0.275157783432022 BEND3 other 0.000130426776288068 1 0.00314950010037312 5.27651856014943 -1.09351328690833 4.98074208396339e-10 180.115627383212 44.3289206879319 4.06316293264156 6.33367294123283e-05 -286.806051804615 80.4382181677487 -3.56554456746542 0.000428570187677133 NT5DC1 other 5.47483169869256e-06 1 0.606322510664218 4.06316293264156 -3.56554456746542 0.87437862263005 6.60890992762828 15.084478482649 0.4381265109848 0.661651496484328 -5.12060097406283 52.4412087857291 -0.0976446022627973 0.922288318059477 GLDC other 1 1 1 0.4381265109848 -0.0976446022627973 0.00636565805818036 93.6326893490377 35.9562717376393 2.60407113485635 0.00971673651868789 -79.4156276009484 91.789098826709 -0.865196723969142 0.387690463717092 COX14 other 1 1 1 2.60407113485635 -0.865196723969142 3.27637822728166e-05 39.4727681738893 8.92985434413986 4.42031489570633 1.43292339450864e-05 8.90465742635516 28.6621425470099 0.31067661504196 0.756287962696699 MCMDC2 other 0.255655793074788 1 0.145212456799506 4.42031489570633 0.31067661504196 0.0631897415691454 0.552014203372536 3.79284720422602 0.145540849301147 0.884392458485071 -12.0095232584359 6.49384161234447 -1.84937113889665 0.0654971032674318 TUBAL3 other 1 1 1 0.145540849301147 -1.84937113889665 0.166058407350606 16.9293741829382 76.2753172518118 0.221950885199839 0.824518058775103 -313.120461350311 182.172135385538 -1.71881644076709 0.0867814182650067 P4HTM other 1 1 1 0.221950885199839 -1.71881644076709 3.25038632186069e-05 125.930268477718 41.7065680244203 3.0194349341807 0.00277212177612784 -257.957650024985 111.697659991053 -2.30942752109264 0.0216664175611391 DTX3 other 0.253757660147664 1 1 3.0194349341807 -2.30942752109264 6.57345023675029e-10 17.0851249629792 4.09558093940074 4.17159988186659 4.07657530662054e-05 -22.1450472971674 7.63269094343754 -2.90134206419131 0.00402067601074945 KLHL11 other 7.17886500355499e-06 1 0.397139966370973 4.17159988186659 -2.90134206419131 2.68498485362173e-09 90.9349753967098 13.9658010266138 6.51126098842599 3.56305345459866e-10 106.919500858091 32.1881938027471 3.32169930109486 0.00101674625270801 CTXN1 other 2.83265902057092e-05 1 4.67543874312437e-06 6.51126098842599 3.32169930109486 0.542247217272679 -0.903440832910002 23.2999894242883 -0.0387743022736413 0.969098672424329 -58.9697604536979 55.5874396360416 -1.06084685389005 0.289697111999904 SLC25A20 other 1 1 1 -0.0387743022736413 -1.06084685389005 0.382601151698422 41.9962530877973 33.5121560859405 1.25316476147042 0.211254506429566 101.819227069498 101.75990098518 1.0005830006097 0.317944672577651 CA8 other 1 1 1 1.25316476147042 1.0005830006097 0.163437317460031 -12.411565960415 7.10610868095936 -1.74660514180869 0.0818601199328218 3.28236986659689 15.4197851218343 0.212867419400617 0.831593418609263 CD28 other 1 1 1 -1.74660514180869 0.212867419400617 4.05703353016702e-12 217.030710902801 31.6947491633682 6.84752890089562 4.99165593384102e-11 -77.9782066697768 98.9280044109508 -0.788231877657738 0.431247495016979 EPM2AIP1 other 4.88182844684998e-08 1 6.73474218593831e-07 6.84752890089562 -0.788231877657738 0.65632811364712 2.23622379507658 8.98958441262217 0.248757194152015 0.803738419094035 -10.0398551220112 15.5642949009748 -0.645056855186061 0.519440104608008 ERBB4 other 1 1 1 0.248757194152015 -0.645056855186061 0.010225265778925 464.083014498589 188.814163575363 2.45788242635386 0.0145975680511549 -8.32971247964248 316.074482962849 -0.0263536379196468 0.978994526333916 MAF other 1 1 1 2.45788242635386 -0.0263536379196468 1.24143688474815e-14 339.919153136766 77.5641634855425 4.38242530908137 1.67565290835675e-05 -472.853415365172 123.246713656527 -3.83664116743066 0.000154992022279706 CTNNBIP1 other 1.62429602000449e-10 1 0.168905813162361 4.38242530908137 -3.83664116743066 0.176272103443431 -5.18619440961991 15.084594956029 -0.343807336208727 0.731257781580124 -36.9297645726959 22.7081871239125 -1.62627533282072 0.105053322828304 PSAPL1 other 1 1 1 -0.343807336208727 -1.62627533282072 0.0628729095823671 66.2833384801459 29.3754924687721 2.25641624733982 0.0248386640194365 78.1683809842423 64.9061596460337 1.20432916398897 0.229509296779993 ERN1 other 1 1 1 2.25641624733982 1.20432916398897 0.0102319996539652 -7.60338079773499 15.1850345487207 -0.500715409855657 0.616974864442186 -69.1047320570178 24.3929255941669 -2.83298252971931 0.00495540949175409 GPR35 other 1 1 1 -0.500715409855657 -2.83298252971931 0.903677377123221 6.86197645783843 15.2827014609598 0.449002846477608 0.65378844702185 5.21256162521229 36.8376894078892 0.141500775672862 0.887579477496574 CSRNP3 other 1 1 1 0.449002846477608 0.141500775672862 3.53367597250266e-05 28.6197121271195 6.42134207384442 4.45696737504363 1.27839967469994e-05 -5.90358892349262 20.0375967431823 -0.294625598027432 0.768535652421346 ZNF713 other 0.274743306862082 1 0.130179438874695 4.45696737504363 -0.294625598027432 0.0421399710236845 129.910900604064 63.2692736604641 2.0533015963046 0.0410102550600176 -213.790031333786 239.730406272124 -0.89179355534528 0.373300600767698 PARP10 other 1 1 1 2.0533015963046 -0.89179355534528 1.90952650674105e-16 323.73235908907 56.0371264829233 5.7771049196772 2.12602128460349e-08 -396.13121981674 109.914939267079 -3.60397979071972 0.000374245401715068 SUZ12 og 2.61681512483794e-12 1 0.00025956593863724 5.7771049196772 -3.60397979071972 4.41696329742461e-11 136.367369108908 19.4632100092344 7.00641718628157 2.55991656975663e-11 26.8077042128745 74.5279691936921 0.359699915386175 0.719394584253843 NSUN3 other 5.10600957182285e-07 1 3.48097455155507e-07 7.00641718628157 0.359699915386175 0.415395859690661 245.221054512249 185.104551133166 1.3247705310921 0.186456915592579 247.302203517687 375.158064205382 0.659194689154543 0.510377480536303 KCTD12 other 1 1 1 1.3247705310921 0.659194689154543 1.0007063712827e-10 65.6243374948559 10.7180495077382 6.12278730822024 3.82745832872028e-09 -63.4370737226355 41.0412497810068 -1.54569059327216 0.123524884067364 DHFR2 other 1.13860370924546e-06 1 4.83867281916818e-05 6.12278730822024 -1.54569059327216 0.00914696619099148 -16.0764499913738 50.3059499257001 -0.319573529873069 0.749541547217418 -278.762757022538 94.3956145129172 -2.95313249943822 0.00342577780739339 RPP25 other 1 1 1 -0.319573529873069 -2.95313249943822 2.31578802378525e-12 867.608013348542 121.542566143152 7.13830586995077 8.8038669021761e-12 -423.027348108171 460.530792833518 -0.918564740275892 0.35914617191731 GRINA other 2.81484034291097e-08 1 1.21334893645791e-07 7.13830586995077 -0.918564740275892 8.76259690122349e-05 1083.66619599161 271.047650388424 3.998065264313 8.27825544745824e-05 -462.688588479899 872.213894435515 -0.530476058030863 0.596224476214531 THBD other 0.653952606738309 1 0.783205747884024 3.998065264313 -0.530476058030863 2.7677243069314e-06 538.432473748805 126.675187582001 4.25049675494075 2.95089588199505e-05 -251.504765503692 237.697174847168 -1.05808899775692 0.290971196393431 COX5A other 0.0237415391048576 1 0.291519004182291 4.25049675494075 -1.05808899775692 0.114836042552218 1.660766531349 3.31062725517164 0.501647090820828 0.616385423740174 -22.4138586173403 12.6769595543677 -1.76807841984617 0.078345301517239 STX19 other 1 1 1 0.501647090820828 -1.76807841984617 0.123058499647035 30.2234405214159 15.1170417424972 1.99929596254612 0.0465710156465904 34.5034480512298 24.1651763104392 1.42781693822463 0.154491669236757 ERFE other 1 1 1 1.99929596254612 1.42781693822463 0.000160770374355961 92.0536535080806 50.0908287865587 1.83773468593081 0.0672084015940724 -263.197729223976 94.080869302712 -2.79756906132657 0.00552223985925382 FAM219B other 1 1 1 1.83773468593081 -2.79756906132657 0.147924650183069 59.89546776815 35.9987204925655 1.66382212891483 0.0973124446981177 -114.95367350953 155.046916632349 -0.741412186751899 0.459090325385357 ZHX2 other 1 1 1 1.66382212891483 -0.741412186751899 0.657821048958085 7.85072974469074 33.6522275072698 0.233290047233716 0.815716968351914 -32.0718853650522 54.7585631339786 -0.585696255151572 0.558579996646414 CPNE7 other 1 1 1 0.233290047233716 -0.585696255151572 0.410067399006546 1.39234129022464 4.11427832142803 0.33841689391139 0.735309163905043 8.86802802841612 6.81618220466919 1.30102567128287 0.194346675617952 C5orf46 other 1 1 1 0.33841689391139 1.30102567128287 0.492740620537992 -1.99808661736027 1.69030685090865 -1.182085144059 0.238200502371752 -0.537003596391448 3.82162956296309 -0.140516914981965 0.888355209791634 CD300LB other 1 1 1 -1.182085144059 -0.140516914981965 1.52317090318152e-11 403.141865096748 66.5227575932965 6.06020976402476 4.59257888505316e-09 -189.318974529695 124.943408092907 -1.51523779781099 0.130890716527711 MPI other 1.79536154358006e-07 1 5.78389384783595e-05 6.06020976402476 -1.51523779781099 0.600233781635163 0.552855118442083 1.91645884209605 0.288477428420753 0.773201828916355 -4.52405488424412 5.56307866303932 -0.813228638002479 0.416800873459906 ADORA2A-AS1 other 1 1 1 0.288477428420753 -0.813228638002479 0.00116676951497121 10.3233829725483 4.20719656572729 2.45374391504423 0.0147746260943849 -27.8550354780276 14.2940472115689 -1.94871578816972 0.0523728114803502 TRIM73 other 1 1 1 2.45374391504423 -1.94871578816972 6.6006540359838e-05 192.001922020868 45.7299572423887 4.19860270157644 3.65395977117788e-05 -64.8216235423332 173.273069126052 -0.374100971774079 0.708623899779849 OPLAH other 0.499603503983614 1 0.357649582402891 4.19860270157644 -0.374100971774079 0.0947571986519523 7.43286289382041 14.1142392982825 0.526621572494161 0.598890369823492 -34.1377624897895 22.5416749223367 -1.51442883492043 0.131091191264977 TMEM52 other 1 1 1 0.526621572494161 -1.51442883492043 0.200941455363745 -3.23092051678065 16.3191056553604 -0.197983920504821 0.843205528353191 -76.5472666962499 44.3076697960399 -1.72763016084162 0.0851896290121491 TMEM139 other 1 1 1 -0.197983920504821 -1.72763016084162 1.03156429134324e-07 20.5948433497446 3.80291232591951 5.41554513612537 1.35532965996267e-07 -1.79872690196626 8.10324521041797 -0.221976116390224 0.824500903384385 EFCAB13 other 0.00098782596539029 1 0.00159061488893219 5.41554513612537 -0.221976116390224 0.758433289381627 59.8043758993463 80.9390483474213 0.738881629082702 0.460618336738611 83.1670479282725 259.738182844407 0.320195694824326 0.749066723323903 MSC other 1 1 1 0.738881629082702 0.320195694824326 2.80937406102251e-17 484.307778693976 53.8025713716094 9.00157309116152 3.96230433605454e-17 -99.457146581559 232.813092726338 -0.427197394342709 0.669573529011243 APOLD1 other 3.92666212509116e-13 1 5.93870173887854e-13 9.00157309116152 -0.427197394342709 0.207846130356153 -10.6694344233036 18.7343770154266 -0.569511033888021 0.569481140882567 -68.5240419469076 38.5919777011546 -1.77560327375649 0.0769205199826705 RFLNA other 1 1 1 -0.569511033888021 -1.77560327375649 9.11015932616424e-10 110.780367657909 18.2667601946494 6.06458761583556 4.56069603965942e-09 -111.234052101036 66.5617024586029 -1.67114193285872 0.0958785801613639 DPY19L3 other 9.86539153430325e-06 1 5.74510880115897e-05 6.06458761583556 -1.67114193285872 2.71800279519158e-12 690.94187372911 123.628827191075 5.58884112571273 5.53363429811985e-08 -442.321220938246 215.67619764261 -2.05085784047066 0.0412353023042286 TAF7 other 3.29388161604301e-08 1 0.000663372079658608 5.58884112571273 -2.05085784047066 0.0034809464547339 6.10767596908373 2.16913100920575 2.81572479631838 0.00522278038451839 -4.89303203728837 5.69508778538795 -0.859167096570937 0.391004875566729 ZNF852 other 1 1 1 2.81572479631838 -0.859167096570937 9.90391878736524e-14 682.481750349902 188.549359002028 3.61964503068166 0.000352619545519645 -1878.59865524528 364.30857628386 -5.15661386401599 4.89216508486854e-07 FOXE1 other 1.26245252782545e-09 0.00768754821436242 1 3.61964503068166 -5.15661386401599 2.40874293480902e-19 322.862010031166 32.6958567298717 9.87470714404594 7.31235668449051e-20 114.139726991431 97.3459381480254 1.17251658531318 0.242011837439139 PFAS other 3.48906414107087e-15 1 1.11900994342758e-15 9.87470714404594 1.17251658531318 3.07765876975262e-16 224.079195270459 30.7137219119441 7.29573562959552 3.31304008986386e-12 -80.4987660451827 58.739170390907 -1.3704443816531 0.171686526297933 HYI other 4.20008092308139e-12 1 4.61373962914441e-08 7.29573562959552 -1.3704443816531 8.46339110215991e-06 199.848830005384 54.1000018323693 3.6940632760905 0.000268631792751847 -200.331193463804 117.834072689611 -1.70011261506254 0.0902964553414956 C17orf62 other 0.069755269464002 1 1 3.6940632760905 -1.70011261506254 0.0215230135761715 19.1388114176635 14.3053667395358 1.33787632055384 0.182058339811717 -60.7501845601804 34.5581832867791 -1.75791024823407 0.0798917115430928 ZNF552 other 1 1 1 1.33787632055384 -1.75791024823407 5.24903966560832e-73 1312.50712425629 54.7678875326769 23.9649032194858 2.70057566817472e-68 231.319336442741 150.181195589222 1.54026831079071 0.124688178224302 GAK essential 8.37746730631088e-69 1 4.3093085937064e-64 23.9649032194858 1.54026831079071 5.05184197260029e-07 -13.5440271349668 49.214867938679 -0.275201940028418 0.783369266158834 -397.006495122497 85.1650526047162 -4.66161275053932 4.91259801789138e-06 ZBTB7A other 0.00461283690518133 0.0760470173169585 1 -0.275201940028418 -4.66161275053932 0.970111008979638 -1.0786472991267 32.0139868561621 -0.0336930012488925 0.973146671345614 10.5270179425612 55.5287840010352 0.189577678170747 0.849781471604393 ERICH3 other 1 1 1 -0.0336930012488925 0.189577678170747 4.58218223297935e-20 185.955662284199 25.8392408090535 7.19663799948195 6.01936719840075e-12 -148.551145684598 49.0547330305991 -3.02827345104368 0.00269577975897221 RMI1 other 6.70419082507209e-16 1 8.32418289866839e-08 7.19663799948195 -3.02827345104368 2.34828419412889e-05 104.65366785447 23.3223234477005 4.4872745243051 1.06433706358384e-05 -3.61912661088793 69.4379558414773 -0.0521202931023801 0.958470959828682 CTC1 other 0.186054556700832 1 0.109083905646708 4.4872745243051 -0.0521202931023801 4.59357235955278e-14 222.420822395041 41.9353307476816 5.30390051609017 2.34466744291677e-07 -232.262853006632 78.3579640451224 -2.9641256742312 0.00330337865441379 FBXO34 other 5.91927734251971e-10 1 0.00271160789773325 5.30390051609017 -2.9641256742312 0.0508634415671174 7.0801152802136 3.91527430380903 1.80833186408564 0.0716551515031779 -12.3270424444169 11.6570137115549 -1.05747859181103 0.29122804282588 LINC00324 other 1 1 1 1.80833186408564 -1.05747859181103 0.000456242208065622 401.564516773463 238.608729707048 1.68294142995725 0.0935296471302752 -1252.75965778841 493.382886342565 -2.53912264179872 0.0116684931232369 SELENOW other 1 1 1 1.68294142995725 -2.53912264179872 1.22827320462866e-38 1347.91077464134 89.4230594024843 15.0734137665156 1.43703034570358e-37 -511.133544725694 421.013090666104 -1.21405618033636 0.225799018236983 EIF3K other 1.94705868397735e-34 1 2.28085456470072e-33 15.0734137665156 -1.21405618033636 8.06764487909918e-28 258.633745154687 54.1200200416524 4.7788922649259 2.89302405078325e-06 -474.101958450081 81.6084236970023 -5.80947329910865 1.75349919636354e-08 MRFAP1L1 other 1.2529052497241e-23 0.000278315392446821 0.0310276829446503 4.7788922649259 -5.80947329910865 5.28170738547014e-11 274.229105439691 52.120226500371 5.26147186712128 2.9071499926751e-07 -110.449288157916 95.4608549919692 -1.15701130235223 0.248286565968457 SNX18 other 6.08505507880015e-07 1 0.00334235034657856 5.26147186712128 -1.15701130235223 4.02196135648763e-21 425.744864333509 40.82369615557 10.4288661837745 1.18537664939477e-21 158.261895719069 121.545094651187 1.30208377535312 0.193985259966584 AURKB essential 5.96295990712855e-17 1 1.82844348169143e-17 10.4288661837745 1.30208377535312 0.0103227528599443 24.4119824550531 8.00558740448089 3.04936805029313 0.00252020178038684 22.9583359736171 14.3230930196619 1.60288953943825 0.11012390505322 C14orf39 other 1 1 1 3.04936805029313 1.60288953943825 1.72024492879627e-33 1245.3611155471 204.393141548999 6.09296919705377 3.78999447067545e-09 -1809.4640829837 308.207611221403 -5.8709260157883 1.26368465213707e-08 MRFAP1 other 2.71282625271172e-29 0.000200698396452409 4.79282700761617e-05 6.09296919705377 -5.8709260157883 0.0026940028132603 24.507354422728 33.029248091406 0.741989474144423 0.45889604805265 -187.124185640406 68.4611158349656 -2.73329149486101 0.00678772603578495 C3orf38 other 1 1 1 0.741989474144423 -2.73329149486101 0.302110643891008 7.1417856476296 20.7676467958757 0.343889980305708 0.731194716431635 -32.0960681139504 31.2714198203924 -1.02637067003335 0.305628781488716 KLHDC7A other 1 1 1 0.343889980305708 -1.02637067003335 9.24464539910652e-07 44.4328213674441 10.9193649575565 4.06917632482789 6.18155974037496e-05 -76.4178041147888 32.7120882677933 -2.33607232559426 0.0202114921327854 TMEM107 other 0.00824714816054293 1 0.592564316712344 4.06917632482789 -2.33607232559426 1.47154408900162e-08 133.071449933777 29.4065658324614 4.52522918493536 9.05059815218897e-06 -220.836055845925 94.4576860229168 -2.33793633047867 0.020121068297816 RRS1 essential 0.000148243351526023 1 0.0932392621638508 4.52522918493536 -2.33793633047867 0.414810999854351 -7.2120746375113 7.83502437202639 -0.92049166601967 0.358137571732084 -17.8325115967713 13.6451166266531 -1.30687865004678 0.192365903260132 EXOC3L1 other 1 1 1 -0.92049166601967 -1.30687865004678 1.07724728291398e-11 1940.20243281298 457.083649292591 4.24474258883631 3.00219566014944e-05 -1734.57698368514 684.602914870296 -2.53369792328998 0.0118463541167068 RCC2 other 1.27621485606819e-07 1 0.296286689700148 4.24474258883631 -2.53369792328998 8.92288565653447e-06 8.5606898533586 2.2534802147051 3.79887508995897 0.0001793516610664 -2.33542693049575 4.301925227322 -0.542879480020527 0.587657349508855 IGSF22 other 0.0734264260676222 1 1 3.79887508995897 -0.542879480020527 0.00155346613881387 85.2471411118467 23.5952304878993 3.61289715544695 0.000361486004620572 69.3182394981361 36.5035306376648 1.89894616458313 0.0586454483616683 ZFP42 other 1 1 1 3.61289715544695 1.89894616458313 0.00221626738088935 7.11752272246879 2.0632481584917 3.44966876290438 0.000651077750135805 3.91277661252294 4.24230249501775 0.922323812862988 0.357183130045567 CCDC89 other 1 1 1 3.44966876290438 0.922323812862988 1.26685831026202e-05 133.093663653135 27.9582970782289 4.76043527546515 3.15898485310563e-06 -57.6791392234938 93.6382310746182 -0.615978522464084 0.538429553891133 DPM3 other 0.102818220460865 1 0.0337569121402867 4.76043527546515 -0.615978522464084 2.60239138109516e-09 899.75940945381 144.887996088895 6.21003419014623 2.00101464339376e-09 -170.406636003787 548.98778122135 -0.31040150952846 0.756496005229755 CYC1 essential 2.74682410274594e-05 1 2.55669640986421e-05 6.21003419014623 -0.31040150952846 0.0337783543587446 67.3260680896292 53.6108990739801 1.25582799864488 0.210284437379508 -228.596073991193 122.478299446132 -1.86642103152104 0.0630869308386532 TMTC2 other 1 1 1 1.25582799864488 -1.86642103152104 6.26235703510294e-39 666.75293098175 53.9152729051276 12.3666800714337 3.90089586725643e-28 -357.404557039456 120.432672370766 -2.96767106470198 0.00326973159928167 FARSA essential 9.92896707915571e-35 1 6.13376866167402e-24 12.3666800714337 -2.96767106470198 1.25680678497521e-20 245.193689212063 37.6003240718064 6.52105255113785 3.38523023321644e-10 -229.542072536007 71.7607526917999 -3.19871327885663 0.00154377035170946 SPTY2D1 other 1.85165343630398e-16 1 4.44548434225983e-06 6.52105255113785 -3.19871327885663 0.140880187146688 1.43455085735429 5.76450948145297 0.248859137446106 0.803658240484438 -14.4469920334848 9.64424391254915 -1.4979911504194 0.135299414927652 C10orf67 other 1 1 1 0.248859137446106 -1.4979911504194 2.70098672111299e-40 700.758424370967 44.637946443403 15.6987155594057 6.60847697659103e-40 -369.450344305857 337.885996232018 -1.09341715379102 0.275185252028605 SAMD4B other 4.28565563038999e-36 1 1.04988873727102e-35 15.6987155594057 -1.09341715379102 0.0409615893191837 -48.8451930216191 27.1479416846083 -1.79922270310873 0.073087720029381 -163.284643402173 68.6467263614493 -2.37862243484738 0.0180655210125763 GIMAP7 other 1 1 1 -1.79922270310873 -2.37862243484738 0.0448186299514771 16.3891838163869 8.97630264883839 1.82582790014414 0.0689684902958445 -30.0423038983139 26.4826786776144 -1.13441333726215 0.25761630272023 ALOXE3 other 1 1 1 1.82582790014414 -1.13441333726215 2.67558669121959e-17 305.906553736734 37.0245750361765 8.26225698574081 6.64271782159533e-15 -50.3149214221358 69.1492545951914 -0.72762782067118 0.467476635674868 EDC3 other 3.74180798767059e-13 1 9.70434646556862e-11 8.26225698574081 -0.72762782067118 1.24794808504804e-07 63.0162446108796 24.1540662186708 2.60892903250256 0.00958510767918571 -255.770474242582 63.454614334525 -4.03076241066081 7.2231848904603e-05 TCAIM other 0.00118779698734872 1 1 2.60892903250256 -4.03076241066081 0.192488162792038 -69.3528528118431 109.270950507936 -0.634687009579974 0.526166048827933 -283.409409616412 161.596502816889 -1.75380905326617 0.0805894940251878 FUCA1 other 1 1 1 -0.634687009579974 -1.75380905326617 0.000374921260521696 1.97407478752845 0.536842503911424 3.67719540301928 0.000285281671974583 -2.59980598588793 2.87543634308721 -0.90414311975227 0.366737627157761 GGN other 1 1 1 3.67719540301928 -0.90414311975227 0.0889071260265972 4.78610226559037 2.2579716687582 2.11964673065297 0.0349382843316214 6.50512471682629 4.03478623240742 1.61226006586845 0.108060764913107 HNRNPCL1 other 1 1 1 2.11964673065297 1.61226006586845 0.128152473586309 88.8453257828628 76.0283482288234 1.16858156007104 0.243603000326095 -129.741475064362 142.251713583877 -0.912055621655912 0.362553049598336 TMEM125 other 1 1 1 1.16858156007104 -0.912055621655912 3.11808052019797e-08 812.304466711871 175.592465379797 4.62607814609186 5.77058492939958e-06 -911.204990169915 361.718817805491 -2.51909755676549 0.0123392456792613 ZNF664 other 0.000308534067473589 1 0.0604007124560254 4.62607814609186 -2.51909755676549 0.00765739537695137 2314.92452509599 791.938796284841 2.92311039180782 0.00375916364238464 535.858796343491 1768.98493602173 0.30291880130341 0.762184995903994 CALR other 1 1 1 2.92311039180782 0.30291880130341 4.67010041524462e-05 127.404497330029 38.8612253270603 3.2784477652925 0.00118388987915501 -128.765349455719 90.1947362130149 -1.42763707575585 0.15457814428755 LDLRAD3 other 0.358476907874177 1 1 3.2784477652925 -1.42763707575585 0.395221900528439 19.3293179724203 16.8908638162686 1.14436527241449 0.253478212538877 -19.7012426805961 50.3312284857229 -0.391431786454103 0.695784565700826 CDH4 other 1 1 1 1.14436527241449 -0.391431786454103 6.56374624695537e-31 1168.99923190365 128.565366124099 9.09264498788315 2.12250702785571e-17 -1332.00406322968 286.233247812251 -4.65356164390584 5.10968993107086e-06 RAD23A other 1.02998306107224e-26 0.0790673419933904 3.18991581216435e-13 9.09264498788315 -4.65356164390584 0.055636662368639 3.55224489369045 2.11795618096246 1.6772041488017 0.0946471108369071 -14.1096841217217 8.11591666669337 -1.73852008358168 0.0832466192882958 C2orf71 other 1 1 1 1.6772041488017 -1.73852008358168 2.37934653220002e-21 673.980286807177 83.7628497410368 8.04629127221519 2.68824535335282e-14 -469.577407790031 186.486557384698 -2.51802282360413 0.0123782195713263 GADD45GIP1 other 3.53618481615567e-17 1 3.89150397351355e-10 8.04629127221519 -2.51802282360413 6.33277189301448e-07 463.401388210272 106.108595137305 4.36723705191485 1.79048213714898e-05 -433.349167674795 223.450477246208 -1.93935216883565 0.0534924161657421 PTPN11 essential 0.0057292587316102 1 0.180104598175816 4.36723705191485 -1.93935216883565 9.11310521825165e-07 61.3269511957366 15.3753115976043 3.98866395691728 8.57010314137031e-05 -3.29120905900694 22.3081763096633 -0.147533756830731 0.882821256514253 NSUN7 other 0.00813800295989872 1 0.808887540348799 3.98866395691728 -0.147533756830731 0.00433117434481938 13.3727197138377 4.11035541433029 3.25342175209842 0.00128594288351136 7.06561699563056 7.23671705283117 0.976356674448992 0.32976494878935 RAB39A other 1 1 1 3.25342175209842 0.976356674448992 1.45368617040956e-06 185.484473795418 46.4811892225507 3.99052771449808 8.51458177034675e-05 -137.810595852237 86.8109785000074 -1.58747889072838 0.113583305108565 CLK3 other 0.0127749940655592 1 0.804117102391547 3.99052771449808 -1.58747889072838 0.0967285604249096 898.596237873289 414.090731372164 2.17004673081097 0.0308656762608265 703.666665148453 813.461387472721 0.86502773946606 0.387783040045293 HLA-DQB1 other 1 1 1 2.17004673081097 0.86502773946606 0.0744461704132685 21.6239968922396 22.2352327604933 0.972510480333732 0.33166387862632 -158.987187878046 84.9223906126232 -1.87214687117408 0.0622632022082858 GATA2 other 1 1 1 0.972510480333732 -1.87214687117408 5.41985949403785e-06 100.327306301454 21.7600445183392 4.61062045240298 6.21149170602471e-06 0.990581742639843 40.8889996128728 0.0242261183207815 0.98069020606619 ARID3B other 0.045385903403073 1 0.064841761919192 4.61062045240298 0.0242261183207815 9.43754110613412e-22 495.139157818923 54.0316552629121 9.16387172315248 1.28342214549266e-17 -193.080178441066 128.485212612588 -1.50274241303742 0.134069850045152 PACS2 other 1.40864738550158e-17 1 1.9324487244683e-13 9.16387172315248 -1.50274241303742 2.58123280079633e-13 70.0630184589195 29.1823360918284 2.40087079521157 0.0170329100683442 -198.600128827386 43.3263317145296 -4.58382053057091 6.98719566124052e-06 ELMOD2 other 3.24796523324203e-09 0.107840377835586 1 2.40087079521157 -4.58382053057091 0.0362053409456119 -24.6811033585191 57.388070659622 -0.43007376053652 0.667481274462291 -217.965474856296 95.6867733029737 -2.27790599821096 0.0235053082649945 EGR3 other 1 1 1 -0.43007376053652 -2.27790599821096 0.266911646788281 2.02966310232204 1.3428806026804 1.5114248416954 0.131845420747372 -1.53771299167478 3.64743538681241 -0.421587452168312 0.673660376004964 CATSPERE other 1 1 1 1.5114248416954 -0.421587452168312 0.491835971546956 -4.21559074299647 17.4236980931454 -0.241945809693232 0.809016613118689 -34.1458972097388 30.1690932043788 -1.13181715401319 0.258774530016818 GPC5 other 1 1 1 -0.241945809693232 -1.13181715401319 0.000353446908705143 226.053884784117 204.06702726855 1.10774331262558 0.268980915153077 -846.935329188245 320.120583301259 -2.64567595264941 0.00864190885601456 VWA1 other 1 1 1 1.10774331262558 -2.64567595264941 0.0747905228735392 33.5197433467304 21.8058610922434 1.53718962094342 0.125486750088019 -73.262977458741 64.9557126398997 -1.1278912120462 0.260425965746599 LINC00174 other 1 1 1 1.53718962094342 -1.1278912120462 3.58960238784851e-35 540.141730429664 37.9438746083422 14.2352813465947 1.17125140780687e-34 39.1558553159614 114.303220639008 0.342561260278249 0.73219606665369 GEMIN4 essential 5.67157177280064e-31 1 1.85643348137389e-30 14.2352813465947 0.342561260278249 1.04649502092226e-05 108.879866093133 26.7740205081351 4.06662369067995 6.29475799268348e-05 -43.1969588889594 61.7722274644588 -0.699294175749339 0.484981535291419 FJX1 other 0.0855509679603944 1 0.60278602537937 4.06662369067995 -0.699294175749339 3.78683152354187e-15 62.4267780577288 14.960195367531 4.17285847705019 4.11921901798253e-05 -115.115282136665 27.1459759505246 -4.24060208210862 3.11248020300451e-05 KLHL28 other 5.02777621380654e-11 0.472754618034354 0.401129547971138 4.17285847705019 -4.24060208210862 6.31735354303704e-08 74.1052482750385 13.7469181896182 5.39068082408486 1.54434385134973e-07 11.0193265041166 28.5751050040499 0.385626807060021 0.70008013725804 MKRN3 other 0.000612467425997441 1 0.0018061101341535 5.39068082408486 0.385626807060021 0.000143513929951223 429.252158740101 101.47830975625 4.22998924372271 3.20005926847693e-05 -31.4908522420268 275.628061988584 -0.114251255894732 0.90912322079897 ZBTB18 other 1 1 0.314821830832761 4.22998924372271 -0.114251255894732 5.56258500556635e-09 13.856385094815 3.61121264992843 3.83704490376372 0.000156783296448021 -15.0046314714131 6.55271467643714 -2.2898343987673 0.0228417634386949 C14orf28 other 5.75671922226061e-05 1 1 3.83704490376372 -2.2898343987673 0.0133171075502911 26.817042040346 14.6168035232042 1.83467212908581 0.0676423763773852 -74.0128500538399 43.1237811538063 -1.71628850888246 0.0872436171803727 ALOX12B other 1 1 1 1.83467212908581 -1.71628850888246 9.61256983720778e-17 348.365331812614 38.4276722719237 9.06548097286494 2.65690649366654e-17 115.244614738558 145.60435030878 0.791491562540275 0.429354540127451 SHARPIN other 1.32663076323305e-12 1 3.98907940959095e-13 9.06548097286494 0.791491562540275 0.0201967536404438 12.1244377458022 4.32308739859818 2.80457844773938 0.00540420313580057 6.91517657389123 18.6260133985056 0.371264447519728 0.710731729755856 LBX2 other 1 1 1 2.80457844773938 0.371264447519728 0.000123401196880959 48.3346185695058 26.156787439202 1.8478805427407 0.0657012213762256 -76.8153625288592 39.7020204581866 -1.93479731364704 0.0540481367444856 DNHD1 other 0.90366696475926 1 1 1.8478805427407 -1.93479731364704 0.180639990055098 12.2158913110488 20.3661092821016 0.59981467946774 0.549129091431415 -32.1781724680148 30.1186364781845 -1.06838078447947 0.286296036449637 HTR1D other 1 1 1 0.59981467946774 -1.06838078447947 8.27886961840092e-29 275.886088836907 29.6415967851354 9.30739632000046 4.46659937196538e-18 -353.169470892348 79.4663319767565 -4.44426541539187 1.28343259824369e-05 GCC1 other 1.29075856220489e-24 0.197032572482371 6.75349825041166e-14 9.30739632000046 -4.44426541539187 0.000392035264057389 49.3548270893371 12.7520298095101 3.87035066782305 0.00013612551507623 7.57017291066271 30.2485745160181 0.250265443307219 0.802571001465002 LSMEM2 other 1 1 1 3.87035066782305 0.250265443307219 0.637434828568004 -70.1238166169655 110.219171182934 -0.636221592526577 0.525172955862163 -198.423578696617 214.177642644769 -0.926443938061821 0.355045748577625 CIITA other 1 1 1 -0.636221592526577 -0.926443938061821 5.40033447264326e-10 26.3361158514027 8.67942663046918 3.03431516535316 0.00264500335424092 -45.0394919590476 14.2213950666239 -3.16702347048571 0.00171615320438286 ZFPM1 other 5.9203866823588e-06 1 1 3.03431516535316 -3.16702347048571 0.422522111998348 -99.584701922425 78.8739411603009 -1.26258052352211 0.207817387434969 -0.73294722931172 232.700848166658 -0.00314974025701354 0.997489175386909 ALOX15B other 1 1 1 -1.26258052352211 -0.00314974025701354 7.86412756227305e-12 103.435191888889 14.1996581669738 7.28434379705443 3.47318793451041e-12 49.2077417415601 36.9183545414033 1.33288014465473 0.183682435674159 PLD6 other 9.36067103737361e-08 1 4.83433028604504e-08 7.28434379705443 1.33288014465473 0.813505181980984 -2.12536465633444 7.32437956233572 -0.290176749886604 0.771901311416913 -12.7299351376595 19.8317690395123 -0.64189609672726 0.521479254254765 GRM8 other 1 1 1 -0.290176749886604 -0.64189609672726 0.531942544818839 -31.7594770591503 232.146275097767 -0.136808040731108 0.891283734402069 -567.723900815149 510.451475474839 -1.11219954901107 0.267034394169436 CDC42EP4 other 1 1 1 -0.136808040731108 -1.11219954901107 9.47614681171291e-17 134.790784657135 18.4993575466583 7.28624139066298 3.68796915711443e-12 -93.6812028678284 43.726328840864 -2.1424438170597 0.0330725192205399 ZBTB42 other 1.30818206735697e-12 1 5.13107148829331e-08 7.28624139066298 -2.1424438170597 0.000435154673369965 12.3040518789439 14.9123713998039 0.825090225361856 0.410040739732427 -70.1056195725106 23.5836903731911 -2.97263144415276 0.00321603061732533 LACC1 other 1 1 1 0.825090225361856 -2.97263144415276 3.5057442551516e-19 560.38968445064 60.528756683909 9.25823881328153 6.80868309921892e-18 -279.42871625903 229.346451942082 -1.21836947505774 0.224151078665431 MAF1 other 5.06615102311958e-15 1 1.02736219284114e-13 9.25823881328153 -1.21836947505774 0.213075974057749 -8.70907288051559 4.99611540968078 -1.74316887549082 0.0824341037881533 2.28173666690277 17.7742369729198 0.128373255649688 0.897948459280743 FCER1A other 1 1 1 -1.74316887549082 0.128373255649688 0.607245906208627 -4.59611418748956 8.39451866753161 -0.547513725267709 0.584510425529504 -45.615060579096 53.5710280407382 -0.851487497018126 0.395307020501465 ARL14 other 1 1 1 -0.547513725267709 -0.851487497018126 0.00507400082225729 20.8467769188528 7.61572416992668 2.73733350285629 0.00660691009456585 -29.8031959964318 28.8563554421491 -1.03281220167186 0.302619440522673 WDR97 other 1 1 1 2.73733350285629 -1.03281220167186 0.0783686909401518 -67.0470297029701 30.372768095754 -2.20747182119179 0.0281285266638696 -90.5460396039603 76.3618007316542 -1.18575045030894 0.236771105248957 PCED1B other 1 1 1 -2.20747182119179 -1.18575045030894 0.0398844274284536 79.7559940059938 53.1912467967057 1.49941952499849 0.134920331367204 -198.318352943354 133.770342417228 -1.48252855872044 0.139353127787501 APOBEC3B other 1 1 1 1.49941952499849 -1.48252855872044 1.4235333409827e-07 81.4837127873016 14.5798649202256 5.58878379416705 5.74814961041102e-08 33.8897987693243 32.9418391619866 1.02877676630853 0.304537027506363 PIPOX other 0.0013499366672539 1 0.000688513360335032 5.58878379416705 1.02877676630853 0.0712454180342484 6.55712119507075 3.01314223276426 2.17617380413378 0.0304256556441257 13.6732732776337 7.90789084891144 1.7290670216466 0.0849616940655441 ATP8B5P other 1 1 1 2.17617380413378 1.7290670216466 0.647070647705652 -1.47341124483983 2.43424040157128 -0.605285839430137 0.545531635197429 -8.96314611314611 11.0223464353548 -0.81317949546535 0.416879739454064 FOXS1 other 1 1 1 -0.605285839430137 -0.81317949546535 0.287055188904429 -296.107567479845 196.826373369105 -1.50441001584966 0.133631837167678 -423.87501286147 340.664472027385 -1.24425952122003 0.214471270968404 CDH5 other 1 1 1 -1.50441001584966 -1.24425952122003 0.308277238760167 51.5722159088705 37.7395621384591 1.3665292596576 0.172897315022312 77.1250276343805 59.6845481131811 1.292210967035 0.197376834130553 FAM216B other 1 1 1 1.3665292596576 1.292210967035 2.92734505383384e-13 1001.61626284751 125.809003996502 7.96140364385496 4.64626379572567e-14 823.716372126609 582.850918441822 1.41325396608915 0.158724405884443 PCBP1-AS1 other 3.67586718409916e-09 1 6.69944776705685e-10 7.96140364385496 1.41325396608915 0.683597275559415 75.9125637968057 349.37594318009 0.217280454703991 0.828153283563964 769.80557020619 888.207073157632 0.866696059365395 0.386875274747244 MYADM other 1 1 1 0.217280454703991 0.866696059365395 0.24158064651484 -8.37161748152858 7.74673123986208 -1.08066450510779 0.280803611613926 -24.8371147349115 14.7847466317562 -1.67991480365066 0.0941220213351532 MRGPRX3 other 1 1 1 -1.08066450510779 -1.67991480365066 6.12425050948087e-07 199.710661935539 40.8104793605377 4.8936122551075 1.70783809488083e-06 -174.816318416861 154.632924186316 -1.13052455896279 0.259262221747394 MROH1 other 0.00554979581169157 1 0.0186222665865806 4.8936122551075 -1.13052455896279 0.00127939945233698 322.079910578932 88.4361225920328 3.64194970492689 0.000325616654356327 -263.892807875135 552.635312764394 -0.477517092700953 0.63338905197185 SERTAD2 other 1 1 1 3.64194970492689 -0.477517092700953 0.21263477392463 -9.04002050143082 6.48459916602271 -1.39407545015237 0.164428420259159 -19.5919193907509 12.0263277387586 -1.62908577051413 0.104448195427229 AKAP5 other 1 1 1 -1.39407545015237 -1.62908577051413 0.274385114116039 3.74690641693646 4.80367021491108 0.780009086657467 0.436063735617605 -14.0689407741791 13.5021823345825 -1.04197532114087 0.298348359181109 NKPD1 other 1 1 1 0.780009086657467 -1.04197532114087 0.701719870189666 -11.0788253996305 13.414666358056 -0.825874092125841 0.409601979848966 -7.69544173898563 22.5941061263731 -0.340595095727336 0.733672300893584 GIPC3 other 1 1 1 -0.825874092125841 -0.340595095727336 0.0433470984464592 113.751634527495 46.2712956391801 2.45836285662976 0.0145807873206088 48.842086605359 92.5466500749358 0.527756397079864 0.598098672217011 CITED4 other 1 1 1 2.45836285662976 0.527756397079864 0.000810585257692465 214.719084047189 109.973473213447 1.95246251457787 0.0519052486877501 -749.99139714092 306.665402193135 -2.44563420515426 0.0150916104836708 ABCA13 other 1 1 1 1.95246251457787 -2.44563420515426 0.331824683294229 11.2894313596697 9.29275652142171 1.21486356966797 0.225475562799223 -5.75223139720372 20.5954554048005 -0.279296149764329 0.780230592759543 NLRP11 other 1 1 1 1.21486356966797 -0.279296149764329 1.6443059722374e-07 83.0744921231576 15.4284307976879 5.38450690238745 1.58424441573604e-07 -33.0654153074838 58.4298946055117 -0.565898938047456 0.571934235480174 TIGD5 other 0.00155156711540321 1 0.00185182329755385 5.38450690238745 -0.565898938047456 0.970384852785849 3.55085142670302 14.6212197082782 0.242856033733807 0.808299959631804 3.89551355124903 21.7993669125047 0.178698471698022 0.858307497649017 C1orf194 other 1 1 1 0.242856033733807 0.178698471698022 0.550674940471181 0.00687381325146733 8.49672692311822 0.000808995430083177 0.999355112500464 -20.6181524751833 20.4007253625984 -1.01065781283363 0.313085077857826 ZNF154 other 1 1 1 0.000808995430083177 -1.01065781283363 4.48447060498158e-08 271.830089038296 66.8891172551803 4.06389111103487 6.31506530798683e-05 -503.878404238405 179.141037735258 -2.8127469317391 0.00526865210839554 R3HDM2 other 0.000439074516933747 1 0.604604352586659 4.06389111103487 -2.8127469317391 0.172139854655089 -54.2638176203494 50.8396855585014 -1.06735155861473 0.286756062072883 106.316666245713 116.915768904547 0.909344113645717 0.363970614652747 B3GNT3 other 1 1 1 -1.06735155861473 0.909344113645717 0.748890738103974 -177.164492318256 233.44359732397 -0.758917761502745 0.448561319631422 -84.7049302941499 823.540580877788 -0.102854591820922 0.918154445459613 ITLN1 other 1 1 1 -0.758917761502745 -0.102854591820922 0.139364418370571 59.691294122853 32.0063500211784 1.86498285756906 0.0632766536018639 -74.2180610125773 146.029885392001 -0.508238849967916 0.611703924938617 NRXN1 other 1 1 1 1.86498285756906 -0.508238849967916 3.68045683564473e-12 581.083254493851 107.503004722525 5.40527454087148 1.43518703754693e-07 -475.099797139947 218.97285206122 -2.16967442615726 0.0309136435185238 SEPHS2 essential 4.43936703515467e-08 1 0.00168146513318998 5.40527454087148 -2.16967442615726 0.808575821716404 1.76744370679296 3.60279303125299 0.490575975766856 0.624120451917111 -0.494790795809534 5.35608135228706 -0.0923792532759529 0.926464475387105 GPBAR1 other 1 1 1 0.490575975766856 -0.0923792532759529 3.24200327629317e-14 25.8841625027156 6.89411894184468 3.75452798552815 0.00021284587290868 -80.6808337197349 15.3625885886656 -5.25177337491553 3.06459823706117e-07 ZNF784 other 4.19580064017863e-10 0.00482459700460541 1 3.75452798552815 -5.25177337491553 1.2736245168704e-19 413.011320510885 54.2871863534328 7.60789696894594 4.5293350975229e-13 -177.878924710811 110.533926539806 -1.60926993439208 0.108713049213399 C14orf119 other 1.85210477243293e-15 1 6.43392050603128e-09 7.60789696894594 -1.60926993439208 0.22327352679851 -3.09543211499167 1.91794314773008 -1.61393319643242 0.107697140109842 -0.497413164780788 5.09684217314724 -0.0975924205386256 0.922327554520236 CCR8 other 1 1 1 -1.61393319643242 -0.0975924205386256 3.80032334937322e-07 85.8787911804109 18.8126548328941 4.5649480067136 7.60792823377581e-06 -76.2213815311605 44.6013994995597 -1.7089459610323 0.0886143383572401 BBS10 other 0.00350351809578717 1 0.0788409602866187 4.5649480067136 -1.7089459610323 1.60422938556106e-16 85.3216815120572 15.9735577941165 5.34143254820059 1.965169612617e-07 -161.887021118608 35.5948597287506 -4.54804492424645 8.19761975064711e-06 FIZ1 other 2.20276736931389e-12 0.126358110836475 0.00228333057289969 5.34143254820059 -4.54804492424645 4.06575020518956e-22 1049.52010729523 100.037490591386 10.4912678345972 8.23732399670495e-22 -50.5682969677546 379.046998241467 -0.133409042156669 0.893969642811991 PUF60 essential 6.09212010745604e-18 1 1.27159570537134e-17 10.4912678345972 -0.133409042156669 0.594127845543138 -12.7967530145679 38.3249860858221 -0.333901047893711 0.738714376809528 -86.1543964069282 84.7188799457506 -1.01694446930952 0.31009361634229 SSC5D other 1 1 1 -0.333901047893711 -1.01694446930952 8.50072957700326e-11 567.438137285821 98.9600487436529 5.73401230587222 2.64860744790437e-08 -198.535053246973 201.571706478774 -0.984935121675323 0.325547616531871 DCTPP1 other 9.70103259327612e-07 1 0.000322203096037567 5.73401230587222 -0.984935121675323 2.27656385036498e-13 149.256491117418 22.6179330412491 6.59903320277828 2.21654747792107e-10 -43.5734329136646 46.0704639703366 -0.945799741494253 0.345105870098712 ZNF771 other 2.86960873338505e-09 1 2.92983245631607e-06 6.59903320277828 -0.945799741494253 5.6231881353226e-10 211.952455622202 44.5603600661762 4.75652475221101 3.22150056763871e-06 -102.126236945468 68.7229199673655 -1.48605788278445 0.138439220377616 TSHZ1 other 6.15907796461885e-06 1 0.0344088475629491 4.75652475221101 -1.48605788278445 2.19802514402629e-08 27.8562663673774 6.8167493237479 4.08644429249187 5.76384768926782e-05 -14.4353765575987 9.47059615050443 -1.52423103342125 0.128608572824865 PSTK other 0.000219274988368063 1 0.55396340141553 4.08644429249187 -1.52423103342125 5.71943045487796e-21 140.884969586998 19.3068180277169 7.29716152007767 3.2073367563805e-12 -110.680322031501 36.292384166733 -3.04968451571045 0.00251593331257587 SOCS4 other 8.46361318712841e-17 1 4.46846156898931e-08 7.29716152007767 -3.04968451571045 1.69311259282594e-19 243.699881098729 36.2923401302786 6.71491229895672 1.11417800792795e-10 -150.032397573608 55.8983766324358 -2.68402065698899 0.00772553362822649 ZADH2 other 2.45721430596828e-15 1 1.48664771597827e-06 6.71491229895672 -2.68402065698899 4.09927584195381e-11 82.6132134973195 16.0739332463995 5.13957674396991 5.32581251929839e-07 -66.8764031911799 32.740991899627 -2.04258940584942 0.0420752556762598 ZNF48 other 4.74409193189314e-07 1 0.00601124459053209 5.13957674396991 -2.04258940584942 0.0107659767049304 -7.2814418949686 13.7000959051663 -0.531488388502651 0.595518991418263 -89.2597913538697 30.3931903044336 -2.93683520748557 0.00360279949986159 FAM71E2 other 1 1 1 -0.531488388502651 -2.93683520748557 0.977801167925157 -0.340371271390266 1.81707767548494 -0.187317953427296 0.851559721741926 1.05893010177283 11.7908660205258 0.0898093575085511 0.928508935901502 C3orf80 other 1 1 1 -0.187317953427296 0.0898093575085511 0.350929187407093 3.87338777349575 5.83970143921569 0.663285240489275 0.507713782727064 -11.4699018678518 12.9385007900341 -0.886493887814777 0.376140350526655 TMEM150B other 1 1 1 0.663285240489275 -0.886493887814777 1.68406192584579e-14 35.1609123886221 5.30003249213004 6.634093742035 1.9816551389855e-10 -19.3010244610624 12.1248755485664 -1.5918534077939 0.11267123867319 ANKRD18A other 2.19433268937707e-10 1 2.62430590055849e-06 6.634093742035 -1.5918534077939 4.62880773782631e-06 10.5049212370603 8.34946807504232 1.25815454860663 0.209418795465768 -72.4963553655243 18.4931469576012 -3.92017408025442 0.000112143375740213 TMEM86B other 0.0390301068453514 1 1 1.25815454860663 -3.92017408025442 0.198687213116977 -37.1327656890572 20.8683481589228 -1.77938212484634 0.0763146128584776 -46.8708836693111 42.5067348206721 -1.10266958558568 0.271163579988369 SEPT1 other 1 1 1 -1.77938212484634 -1.10266958558568 1.24294496102907e-15 38.8223002711953 25.8892290764212 1.49955412564034 0.134889697693312 -241.376434890855 37.5781765515289 -6.4233141956707 5.92998962018306e-10 TRNAU1AP other 1.67014514413476e-11 9.44765946287566e-06 1 1.49955412564034 -6.4233141956707 2.19294441398169e-28 595.589656607065 46.7474606575368 12.7405777389759 2.65511485873461e-29 97.1804821267423 268.903864511906 0.36139488847859 0.718093322925346 EXOC3 essential 3.41266009703831e-24 1 4.18339897142225e-25 12.7405777389759 0.36139488847859 0.121196983738498 -4.32846764250116 2.59549001974274 -1.66768803176912 0.0965242853410233 4.04736652957838 6.56521865826781 0.616486173614551 0.538087421688414 TDRD6 other 1 1 1 -1.66768803176912 0.616486173614551 0.824283997179459 -0.612214978242726 2.10970278363361 -0.290190155216218 0.771891876921105 -2.04319230954138 3.28756809061375 -0.621490491824288 0.534797465564532 CSNK1A1L other 1 1 1 -0.290190155216218 -0.621490491824288 0.140277672171987 -352.013750772524 193.334026075075 -1.82075425582784 0.0697593160048752 -487.876282106608 278.020711011726 -1.75481992090162 0.0804328205380085 ACTA2-AS1 other 1 1 1 -1.82075425582784 -1.75481992090162 0.367490959196332 88.0200476749862 62.1590632615134 1.41604527250791 0.15790634572309 99.5782483248827 232.445374312782 0.428394192051715 0.668703188937773 LYNX1 other 1 1 1 1.41604527250791 0.428394192051715 0.377491693811783 8.08428201558673 37.2900360484864 0.216794695641354 0.828530265790365 -48.341083254186 54.8394683877956 -0.881501675259569 0.378821778975584 TH other 1 1 1 0.216794695641354 -0.881501675259569 0.00608106354697155 114.936921834049 39.7161335016372 2.89396050673742 0.0041123046944076 -39.9570403971824 109.25829035562 -0.365711748436919 0.71486442827969 FAR2P1 other 1 1 1 2.89396050673742 -0.365711748436919 8.43062378685051e-13 136.274064644059 28.9096030577243 4.71379923037887 3.89952840785358e-06 -132.373096485739 52.9753926666455 -2.49876574429025 0.0130572956621517 FAHD1 other 1.04219371253046e-08 1 0.0414051926345893 4.71379923037887 -2.49876574429025 4.69768355545901e-06 72.2306428424726 38.8342941086033 1.85997053636339 0.0640548100585244 -166.98747689464 64.4794555837216 -2.58977802127717 0.0101626640484585 TDRP other 0.0395685885876312 1 1 1.85997053636339 -2.58977802127717 1.08018059510099e-14 456.420197394745 110.119991119349 4.14475330732704 4.54780761844982e-05 -624.117363179657 159.838999296604 -3.9046626037837 0.000119074125927655 RCC1 essential 1.41579270599887e-10 1 0.441091860913448 4.14475330732704 -3.9046626037837 6.04573024027338e-15 272.577359807221 36.2325281503305 7.52300139466627 8.12074456570042e-13 -160.912626046478 102.481065418525 -1.57016933215246 0.117555591760873 PRKRA other 7.9809684901849e-11 1 1.14599947311164e-08 7.52300139466627 -1.57016933215246 0.00619425275447461 29.4595703690841 21.5131912362256 1.36937240252286 0.172078318283128 -87.2303609515219 45.6650255977763 -1.91022253485323 0.0572175585786298 HERC2P3 other 1 1 1 1.36937240252286 -1.91022253485323 2.96971566612162e-10 112.930333536147 22.5303659811242 5.01236125639321 9.70137489546063e-07 -179.343317292624 61.7518302566195 -2.90425913770222 0.00398340013391743 ZNRF2 other 3.30172987759402e-06 1 0.0107694962714508 5.01236125639321 -2.90425913770222 0.514055629131672 28.2935044044576 28.9691768711415 0.976676159295469 0.329600529906956 -46.5106018374352 108.264964509005 -0.429599751391104 0.66782818391657 SLC9A4 other 1 1 1 0.976676159295469 -0.429599751391104 0.00166983122044132 13.7977400700376 9.3960635488618 1.46845963719658 0.143147782048599 -61.0669968994658 23.9919475642384 -2.54531220260294 0.011476733597463 ZNF816 other 1 1 1 1.46845963719658 -2.54531220260294 7.42343407102211e-05 130.687206850161 62.4816758025339 2.09160854236981 0.0374010241713406 -451.987265025635 143.994803626473 -3.1389137221792 0.00188241437448 FGD6 other 0.558242242140863 1 1 2.09160854236981 -3.1389137221792 0.896718707602149 -1.77992057758042 3.92418134296213 -0.453577554659302 0.650495906180451 -1.65836985526422 10.4759192673117 -0.158303038897873 0.874335910644435 PLD5 other 1 1 1 -0.453577554659302 -0.158303038897873 1.08460102957186e-11 294.151254867775 60.4710068466592 4.86433532707131 1.94639987752522e-06 -384.674109770438 119.876196402147 -3.20892822191302 0.00149190517008798 OAZ2 other 1.28481837963082e-07 1 0.0211534738689441 4.86433532707131 -3.20892822191302 0.217045132403507 1.38439156867048 2.87229097807907 0.48198165827765 0.630205146339914 -7.75265958150103 5.62399345397868 -1.37849726265532 0.169178388503594 PNPLA1 other 1 1 1 0.48198165827765 -1.37849726265532 0.0119886245731276 18.409041589482 7.18396118991514 2.56251963266794 0.010946857569601 -14.1757306174514 16.7900943006823 -0.844291304360058 0.399271062984603 ALX1 other 1 1 1 2.56251963266794 -0.844291304360058 1.0692188592995e-16 131.435234212712 18.8090518373415 6.98787133712796 2.15049108854627e-11 -114.667023143897 39.3717715217512 -2.91241716366632 0.00388391923290246 CCDC43 other 1.47402511943029e-12 1 2.9300441081443e-07 6.98787133712796 -2.91241716366632 1.25478700772879e-06 37.4963817643594 10.7696461566794 3.48167258411773 0.000580343981281961 -55.3501691329468 22.5434036504213 -2.45527117338878 0.0147039876807493 MEIOC other 0.0110885527872993 1 1 3.48167258411773 -2.45527117338878 0.00176549864422179 55.7306820751998 17.5793052366005 3.17024372266813 0.00169726275939412 -12.9050422081419 36.6340266421402 -0.352269280529953 0.724909109123928 FZD2 other 1 1 1 3.17024372266813 -0.352269280529953 1.59376411385412e-11 72.8100614598437 18.2003156842534 4.00048343792397 8.15368864052324e-05 -67.2578080368635 28.1950609371934 -2.38544645059237 0.0177432308920368 TIGD2 other 1.87713537329738e-07 1 0.772154314257551 4.00048343792397 -2.38544645059237 0.925873652996791 43.0329141193563 113.350562368549 0.379644469512545 0.704506676745579 72.2581890934953 445.95604154162 0.162029846806665 0.871403091027108 HCLS1 other 1 1 1 0.379644469512545 0.162029846806665 0.0403819371591523 65.1258876639702 43.1709325851633 1.50855873996922 0.13257223136384 -173.757882427693 118.324047787436 -1.46849170288563 0.143126207181421 MTURN other 1 1 1 1.50855873996922 -1.46849170288563 1.12745018003607e-07 381.439751619382 73.737075555192 5.17297097487783 4.46612233903575e-07 -55.5729236985062 146.112403102803 -0.380343643101987 0.70398609872505 ZNF609 other 0.00107660217691644 1 0.00506904885480558 5.17297097487783 -0.380343643101987 4.71542262743992e-23 726.632188287707 65.4240436124376 11.106500732241 9.06108059422539e-24 -133.048224137145 503.978031039436 -0.263996079080546 0.791988899469234 PAK2 other 7.12311742101075e-19 1 1.41062902690901e-19 11.106500732241 -0.263996079080546 7.84328838886454e-09 81.554186727084 14.3850042605919 5.66938912562603 3.64205453746743e-08 -31.1786144151797 35.2210944640759 -0.885225598170456 0.376813989822737 CCDC66 other 8.04407657161947e-05 1 0.000439960188126066 5.66938912562603 -0.885225598170456 0.789532809721858 19.6217661477122 32.7924176831872 0.598362900146039 0.550097581006973 1.38819643104831 51.4930541100603 0.0269589064979755 0.978512351237945 ATP5EP2 other 1 1 1 0.598362900146039 0.0269589064979755 1.20929684209571e-14 640.563198464269 77.8256495229871 8.23074657764428 8.29730753965173e-15 1008.83734683125 321.207967724059 3.14076065416259 0.00187458763667929 MCFD2 other 1.58272770693486e-10 1 1.21041122388439e-10 8.23074657764428 3.14076065416259 1.49881581341551e-12 29.9446648593547 7.17625832421885 4.17274065487522 4.07936638378181e-05 -61.3086878350847 15.3991889273416 -3.98129330865145 8.84918477548498e-05 HARBI1 other 1.83574960827132e-08 1 0.397371079444186 4.17274065487522 -3.98129330865145 1.57628369184779e-07 50.4355968143126 15.9177469383721 3.16851354714843 0.00170703137081703 -66.9410504889765 27.9435814853857 -2.39557876730963 0.0172704064459741 C11orf71 other 0.00148958808879616 1 1 3.16851354714843 -2.39557876730963 0.017741211341709 47.245991942777 16.5201916253505 2.85989369943367 0.00456506971781364 40.865325851626 45.1520524245615 0.905060205621934 0.366231518190272 TPRXL other 1 1 1 2.85989369943367 0.905060205621934 0.707249053432359 3.87555166072265 17.0740630077171 0.226984734621805 0.820606114659458 -14.854292052083 26.0665230810629 -0.569860890379908 0.56924241183836 SERTM1 other 1 1 1 0.226984734621805 -0.569860890379908 0.0241914575823801 6.54851292185745 36.3062734273396 0.180368633397837 0.856996995046845 172.834710864114 68.5283626837284 2.5220901842027 0.0122350813376691 GAS1 other 1 1 1 0.180368633397837 2.5220901842027 0.407684492133727 -57.818417500482 61.5807582054306 -0.938903956128672 0.348616118827648 -140.9012033096 107.072671895327 -1.31593992020059 0.18930626883742 ARHGAP45 other 1 1 1 -0.938903956128672 -1.31593992020059 3.82550925022466e-13 19.0174801922057 2.46990658722388 7.69967588676335 2.63894169707018e-13 -4.52593992128439 12.1330896450727 -0.373024518377511 0.709425058350089 ZNF571 other 4.78461119924327e-09 1 3.76524201337973e-09 7.69967588676335 -0.373024518377511 0.196486572418994 0.445845281239356 1.82861182598617 0.243816251707173 0.80755897724838 -7.01574956225675 4.30886974059877 -1.62821110514282 0.104650728473213 GLIPR1L2 other 1 1 1 0.243816251707173 -1.62821110514282 2.49848125939303e-18 163.873097491777 22.3685293480696 7.32605594859637 2.74424886608716e-12 -66.4626160168056 38.1284388984385 -1.74312450068674 0.0824502388322261 MIGA1 other 3.56108533901289e-14 1 3.82905044285141e-08 7.32605594859637 -1.74312450068674 1.25573716452224e-06 502.509163776611 125.502121568224 4.00398939474057 8.6524522473169e-05 -213.681994189199 205.173138142394 -1.04147158894114 0.298859971491284 NRIP1 other 0.0110956935857185 1 0.81635886953435 4.00398939474057 -1.04147158894114 0.651816433108537 -1.10871045440502 1.22212149690442 -0.907201499370835 0.365124447466584 -0.0574087905429444 5.31318307418694 -0.0108049712839472 0.991387177730168 BHLHA15 other 1 1 1 -0.907201499370835 -0.0108049712839472 0.104771205161813 40.7920469946336 19.2778402774504 2.11600710492185 0.0352528140347168 18.8717817630868 36.594028001038 0.515706600064674 0.606478262339621 RNF182 other 1 1 1 2.11600710492185 0.515706600064674 0.0300343627949026 156.705516494802 79.4771834867916 1.9717044517669 0.0496603313549996 -345.299007044273 289.984232858754 -1.19075097166563 0.23479330906949 TSPYL5 other 1 1 1 1.9717044517669 -1.19075097166563 0.0648686372340556 -3.81443725396157 2.0484444350026 -1.86211409437461 0.0636732727825526 -7.83536677832529 3.85639231289726 -2.03178674330431 0.0431543247386706 FUT7 other 1 1 1 -1.86211409437461 -2.03178674330431 0.000112332929044078 306.286370952034 84.0642828867532 3.64347806742902 0.000322280901259251 -123.210739887105 147.543041272391 -0.835083368382217 0.404406359349087 HIST1H2AC other 0.827332022409638 1 1 3.64347806742902 -0.835083368382217 0.00198183466460086 21.8977697971995 7.50786821832143 2.91664280198238 0.00383439884839031 -1.0056207749879 12.6441748689288 -0.0795323368596443 0.936667909156683 SKIDA1 other 1 1 1 2.91664280198238 -0.0795323368596443 0.00973783148810221 36.1893011966816 12.9304485714384 2.79876610596626 0.00549820730882879 -3.0400832844161 22.6945099837031 -0.133956771333648 0.893536183555079 HIST1H2BC other 1 1 1 2.79876610596626 -0.133956771333648 9.70523735150769e-15 77.8967177440414 9.15288015163016 8.51062359099805 1.23047307204906e-15 13.908432119104 72.3968787304548 0.192113698311322 0.847798090206211 MB21D2 other 1.27352124526484e-10 1 1.81384035550751e-11 8.51062359099805 0.192113698311322 0.916007823251997 18.0288149579772 48.7166070831842 0.370075340575191 0.71161434794725 30.9206968939571 107.119806058773 0.288655273302044 0.77306505060623 SSTR2 other 1 1 1 0.370075340575191 0.288655273302044 2.49561201639995e-13 79.8350323013677 10.5154303971282 7.59217923435366 5.00687189191717e-13 -16.4425816288936 32.6489201470389 -0.5036179314612 0.614936019607602 ZNF594 other 3.14147640624426e-09 1 7.10174709149531e-09 7.59217923435366 -0.5036179314612 1.35746171822663e-05 215.961714497585 91.2046032929886 2.3678817373266 0.0185899569947209 -243.613411811245 130.540102476399 -1.86619595963078 0.0630900778608013 PCGF5 other 0.10991367532481 1 1 2.3678817373266 -1.86619595963078 0.0193280457909494 36.0785248836376 26.3313087252264 1.3701759096035 0.171774428507705 -86.8786852846418 68.7141219010874 -1.26434978547353 0.207198899993587 SLC47A2 other 1 1 1 1.3701759096035 -1.26434978547353 0.353971090827435 45.2163611409315 57.2320508524003 0.790053133995549 0.430184962156725 -40.0197529522075 89.8501989093144 -0.445405279431817 0.656381178585361 PRF1 other 1 1 1 0.790053133995549 -0.445405279431817 0.0264071489866445 0.340737821650165 2.89376420293693 0.117748993267781 0.906353769380405 14.0547072437201 5.40522830914874 2.6002060301378 0.00982791902722165 OR2A4 other 1 1 1 0.117748993267781 2.6002060301378 0.00170546021161126 45.0209306888703 16.7921054646698 2.68107717543778 0.00778526898089659 -102.208727044917 47.8067468122159 -2.13795612251951 0.0334083464259255 YOD1 other 1 1 1 2.68107717543778 -2.13795612251951 0.0281913446772066 113.74093750352 47.5751135385519 2.39076544528583 0.0175012550640711 -88.5012712067275 165.685971158945 -0.534150662169382 0.593678451968579 TMEM64 other 1 1 1 2.39076544528583 -0.534150662169382 0.490155769396607 171.225961413504 194.75618340022 0.879181130088371 0.380081966583943 -56.0133126790143 308.336171141636 -0.1816631259045 0.855982907701572 SHISA2 other 1 1 1 0.879181130088371 -0.1816631259045 6.04903317661899e-05 100.53488199813 37.0166061626477 2.715940017742 0.00703211769281578 -141.926820073488 75.5211252958425 -1.87929959355758 0.061272675654127 S1PR5 other 0.459605540759511 1 1 2.715940017742 -1.87929959355758 2.45758177260347e-08 51.8716383072291 11.3204179261222 4.58213103489171 7.06106323698367e-06 -26.0161717340949 21.8236525855829 -1.1921089575666 0.234273030459212 SMG1P3 other 0.000244504810556319 1 0.0734491797911042 4.58213103489171 -1.1921089575666 1.81480943058957e-05 180.061178168367 79.4033227068982 2.2676781276903 0.0241305568543069 -297.66792997401 125.916156234514 -2.36401696871699 0.0187783742746348 GPR157 other 0.145438827767448 1 1 2.2676781276903 -2.36401696871699 0.99844505236664 -1.92916294391692 36.7603148651599 -0.0524794999986606 0.958185150346333 -0.461294084749528 62.2366079698279 -0.00741194129624098 0.994091613807232 PIPSL other 1 1 1 -0.0524794999986606 -0.00741194129624098 0.000301924879216955 -2.54072932583135 5.48340308026002 -0.463348998540314 0.643486128155326 -29.1125308555499 8.33939702483783 -3.49096352755984 0.000561682766180132 WDFY3-AS2 other 1 1 1 -0.463348998540314 -3.49096352755984 0.000840583771749572 103.809365648897 29.7685738426968 3.48721326716714 0.000569905747217631 28.5375983597471 54.660498658906 0.52208814518558 0.60203860583695 SLC36A4 other 1 1 1 3.48721326716714 0.52208814518558 8.29286665485087e-15 416.417837415187 113.404652103263 3.67196433031696 0.000291920069535394 -729.867909299572 172.270912458432 -4.23674489723089 3.14743862714454e-05 ZDHHC20 other 1.08976560711395e-10 0.47797002991817 1 3.67196433031696 -4.23674489723089 0.000260676241237352 30.7383169729005 11.4195999563332 2.69171574227111 0.00754756585093814 -80.9465486234979 35.4562384044 -2.28299876879925 0.0231992840550882 ZFP3 other 1 1 1 2.69171574227111 -2.28299876879925 0.00136189300940906 105.197424958253 53.6174629497544 1.96199930341417 0.0507935200779634 -94.700041746426 76.105047242802 -1.24433326273748 0.214460037267315 ARSJ other 1 1 1 1.96199930341417 -1.24433326273748 0.000616301120046544 26.0354464997336 7.5045451469827 3.46929040865341 0.000606561184628905 -11.4623615135021 20.5913388996594 -0.556659359032342 0.578217888241081 HOXC9 other 1 1 1 3.46929040865341 -0.556659359032342 2.55258732967466e-09 656.256381761724 168.014011726089 3.90596221719655 0.000118469880417228 -430.377313286487 262.936852174043 -1.63680864712571 0.102826898431137 PPA1 essential 2.69553222013644e-05 1 1 3.90596221719655 -1.63680864712571 0.0368453666834617 80.177685778716 31.0163703202689 2.58501188084928 0.0102586333554361 73.1579832059741 85.1042375244793 0.859627973106875 0.390751142627299 HOXC10 other 1 1 1 2.58501188084928 0.859627973106875 1.78100156184732e-05 165.588747074558 57.174288634998 2.8962100102667 0.00409088748904732 -241.57746807202 102.909380879652 -2.34747761581167 0.0196342951254842 PSMG4 essential 0.1427828952133 1 1 2.8962100102667 -2.34747761581167 0.689963560985134 -0.567538237883665 2.42526530599132 -0.234010784915626 0.815157289533204 -6.54105404413561 7.62932662225756 -0.857356666976735 0.392022491282128 BHLHE22 other 1 1 1 -0.234010784915626 -0.857356666976735 4.47747543289257e-17 38.6190495193426 4.15568568327513 9.29306315796883 5.72133688849371e-18 48.1265714125605 47.2167246883009 1.01926958572976 0.309004627822419 MAP6D1 other 6.23309355012975e-13 1 8.64093510269205e-14 9.29306315796883 1.01926958572976 2.48921329218227e-12 22.6801286503419 4.24091428658406 5.34793375147654 1.90750118211347e-07 -22.330127184077 9.29233668779368 -2.40306910245833 0.0169381176309187 ZNF443 other 3.02165601538006e-08 1 0.00221747012420691 5.34793375147654 -2.40306910245833 0.304475424368901 -13.7731498161217 10.4710548203296 -1.31535457052341 0.189494423056637 20.8282881216863 44.065156550981 0.472670239979498 0.63682611640957 LINC01559 other 1 1 1 -1.31535457052341 0.472670239979498 0.000809011331276462 -26.6872011519071 17.8687351420624 -1.49351372325657 0.136457598850578 -99.996322702411 26.5645010005117 -3.7642838726948 0.000204511259852797 CXCR2 other 1 1 1 -1.49351372325657 -3.7642838726948 0.660065608890395 -3.90272222605336 4.42193171271861 -0.882583106118108 0.378246654214769 -3.81672901868837 12.0015405880688 -0.318019923415727 0.750715652440949 GREM2 other 1 1 1 -0.882583106118108 -0.318019923415727 0.0881684418670257 9.67574488598975 4.99801787455843 1.93591642303692 0.0539255818352931 -4.93036368484584 11.7771348060939 -0.418638638855921 0.67581429501468 CAPS2 other 1 1 1 1.93591642303692 -0.418638638855921 1.82479787911051e-05 18.1612039381153 3.86331399993566 4.70093912594673 4.12001082743531e-06 3.89916736990154 16.1171308100688 0.241926892314209 0.809019108814929 ZNF792 other 0.146202806074334 1 0.0436432746950222 4.70093912594673 0.241926892314209 0.00040375316212802 213.651008501317 54.2652272564971 3.93716232849162 0.000104806992605767 40.5469676961013 116.441540233833 0.348217376845724 0.727946287542514 CUEDC1 other 1 1 0.98067902981216 3.93716232849162 0.348217376845724 1.78410555447472e-16 206.597074069641 23.6383284281843 8.7399189285869 2.45127611760528e-16 -19.4051920322541 53.3183222889463 -0.36394978684986 0.716178247153574 KCTD2 other 2.44618712574028e-12 1 3.64749886299666e-12 8.7399189285869 -0.36394978684986 4.05355610364203e-05 46.6373003421644 52.4465304486961 0.889235187593308 0.374677152012092 -290.693854498184 84.7023224721195 -3.43194668120073 0.000694324317376816 D2HGDH other 0.313258815689456 1 1 0.889235187593308 -3.43194668120073 0.043391645522591 16.6033494713961 6.63952051785408 2.50068501584544 0.0129883832609693 9.2511343512726 18.4794643938458 0.500617017577278 0.617048510265552 OXTR other 1 1 1 2.50068501584544 0.500617017577278 3.11113397232072e-15 129.079652486533 25.9949695475625 4.96556275052982 1.21595904577997e-06 -148.349100854249 45.1260284514463 -3.28743977577966 0.0011450130465166 CMTR2 other 4.13905263677549e-11 1 0.0134035165616327 4.96556275052982 -3.28743977577966 2.29884794125393e-05 740.632957377605 162.771392547433 4.55014204760692 8.12213901480747e-06 -1.46479856674649 616.7488546539 -0.00237503248801085 0.998106760364786 FAM83H other 0.182436572617912 1 0.0840316502471981 4.55014204760692 -0.00237503248801085 0.000263760019498094 11.8692116327089 2.87949732437858 4.12197348899098 5.00763649523445e-05 9.45412966141751 12.6352801425013 0.748232690909372 0.454973480258776 ZNF572 other 1 1 0.483286998155077 4.12197348899098 0.748232690909372 0.000313597007034799 27.6559994979762 7.78506087864756 3.55244485933689 0.000449745218051222 -9.30123686109646 15.3237724861859 -0.606980876900993 0.544369928477439 ST20 other 1 1 1 3.55244485933689 -0.606980876900993 5.8888459564787e-29 661.623903314179 64.2102129684156 10.304029105769 3.10157332149834e-21 -712.775671748564 180.785861885854 -3.94265162282768 0.000102563427323885 PITPNB other 9.18601080751113e-25 1 4.77580260044314e-17 10.304029105769 -3.94265162282768 8.89583419720338e-14 88.4245979086418 22.8008880507149 3.87812078687301 0.000132072717498262 -173.858568053125 39.8205611801655 -4.3660501735903 1.79959060095812e-05 LRRC57 other 1.13599802698287e-09 0.275229386510535 1 3.87812078687301 -4.3660501735903 3.02725753963441e-18 469.56135719472 52.262361825134 8.98469454491623 4.60568131273505e-17 -62.6739470371178 127.068251052096 -0.493230578985638 0.622250594856416 MRPL14 essential 4.30960383342355e-14 1 6.89700776582074e-13 8.98469454491623 -0.493230578985638 0.213823154965475 7.29416779476034 5.97820791466754 1.22012614798226 0.22348562808571 -6.66098638324582 11.3891753325247 -0.584852387356235 0.559137201066688 GPR137C other 1 1 1 1.22012614798226 -0.584852387356235 4.76355397838262e-07 19.8673865528399 7.65695825020301 2.59468393370346 0.00998323432654577 -28.582968176216 11.5268338579709 -2.47968943843592 0.0137578467453383 BBS12 other 0.0043586518902201 1 1 2.59468393370346 -2.47968943843592 3.57765483195736e-06 32.5471048221934 6.37723768256116 5.10363678480964 6.32083156055246e-07 18.3388932668841 25.924311108319 0.707401372798649 0.4799317635071 ZFP82 other 0.0303993331071417 1 0.00710208634143674 5.10363678480964 0.707401372798649 0.00346435499874132 5.49123206334249 1.7923551258101 3.06369646520836 0.00240984784052457 -2.1405161144456 5.17453941816288 -0.413663118872432 0.679452905922888 LSMEM1 other 1 1 1 3.06369646520836 -0.413663118872432 0.000132494999955639 2440.09180770639 838.369000016353 2.91052246404483 0.00390681918771022 -1852.27696000749 1546.28149683893 -1.19789117556804 0.232002167336638 NQO1 other 0.967213499676165 1 1 2.91052246404483 -1.19789117556804 7.00960525844524e-08 165.577813803992 30.0302919593566 5.51369310788212 8.18977235327404e-08 -20.5315966907792 61.9954059781695 -0.331179324771404 0.740764974884675 AEN other 0.00067775873243907 1 0.000972044080610096 5.51369310788212 -0.331179324771404 8.71452683253815e-14 99.4796068773506 17.8955438588486 5.55890380655642 6.49571336985571e-08 -126.635037568897 41.2304199885492 -3.07139819589678 0.00234729404191886 FKRP other 1.11319365758842e-09 1 0.000775133476424882 5.55890380655642 -3.07139819589678 6.86580192710917e-24 346.176282984166 33.2815831395765 10.4014367805873 1.49472061107596e-21 57.7938860692188 74.2067833644847 0.778822143325497 0.436761516435382 TRAPPC5 other 1.04408249905549e-19 1 2.30456023815692e-17 10.4014367805873 0.778822143325497 0.000305894556120475 -18.4728637962173 30.4299314277422 -0.607062288000296 0.544325458078784 -371.394833709205 91.6654912150729 -4.0516319586158 6.67362792152627e-05 RPH3AL other 1 1 1 -0.607062288000296 -4.0516319586158 0.114937647419909 20.7182235966155 14.7281254621173 1.40671150920771 0.160654468138424 -25.4925460636516 34.0655537882311 -0.748337931686837 0.454902915923374 SLC25A42 other 1 1 1 1.40671150920771 -0.748337931686837 0.403188157200339 -1.54875093738283 2.46597470821435 -0.628048184040096 0.530499328385688 10.5945491188601 9.19073253910636 1.1527426213069 0.250028092131516 FCRL6 other 1 1 1 -0.628048184040096 1.1527426213069 1.02797460561951e-22 145.730151947808 14.3876897389046 10.1288083488311 1.14463605086921e-20 -49.6222773412262 31.7552480487598 -1.56264807835958 0.119298081966958 METTL23 other 1.54812975606299e-18 1 1.75793204692493e-16 10.1288083488311 -1.56264807835958 2.62247859631112e-08 122.574294639108 22.4788069552438 5.4528825699317 1.11918145638821e-07 -52.438110779255 50.5887325402687 -1.03655711748687 0.300869749466313 SLC26A11 other 0.00026054324854351 1 0.00132041028224681 5.4528825699317 -1.03655711748687 0.00471907247313476 342.105343511448 128.29073282402 2.66664112037402 0.00812030663251439 -325.335625367006 337.217523883555 -0.964764884162272 0.335519545679519 HIGD1A other 1 1 1 2.66664112037402 -0.964764884162272 0.0703824140023623 23.9655514721413 11.8577441173703 2.02108860124874 0.0442610207033395 -25.2106296326667 44.9295787712574 -0.561114310931278 0.575186724741058 MAPK15 other 1 1 1 2.02108860124874 -0.561114310931278 2.46652826293486e-13 380.9145629268 73.3575397443733 5.19257549059252 4.13641810489953e-07 -512.907778880718 138.838936532776 -3.69426467595879 0.000267851933209866 EHMT1 other 3.10634569434016e-09 1 0.00470848472880714 5.19257549059252 -3.69426467595879 0.866288468163524 -2.63024042727919 95.1390932358057 -0.0276462633584287 0.977964630456068 -71.6750541147974 148.798513469049 -0.48169200379617 0.63041350847049 F2R other 1 1 1 -0.0276462633584287 -0.48169200379617 0.000374231323087799 303.658859708588 77.8042762781663 3.90285565568331 0.000120018347153869 537.531604436966 213.114348203208 2.52226848623266 0.0122332631431295 MUC16 other 1 1 1 3.90285565568331 2.52226848623266 5.15620708938707e-18 2765.36395720692 345.409231660899 8.00605109455148 3.46569916639499e-14 -454.046408781426 559.76775764367 -0.811133550622358 0.417998169679077 NPM1 essential 7.30840792849723e-14 1 5.00724215560749e-10 8.00605109455148 -0.811133550622358 1.42100457811673e-14 335.833535971826 64.0710505268878 5.24157998362913 3.20653651032812e-07 -262.532048008171 108.606803415666 -2.41727073950785 0.0162977944448656 DHTKD1 other 1.8552635771892e-10 1 0.00367725607004429 5.24157998362913 -2.41727073950785 0.0343612939027678 1040.68471525288 404.167939309302 2.57488190931559 0.0105789888534373 582.398560334525 1237.61701384693 0.470580602737705 0.638333277797404 PENK other 1 1 1 2.57488190931559 0.470580602737705 0.000882955433440707 152.683792931806 42.3136987039715 3.60837737206546 0.000366617951540772 -89.6016061058569 119.218706812322 -0.751573377212612 0.452957459201524 HIST3H2A other 1 1 1 3.60837737206546 -0.751573377212612 2.12189799544998e-09 185.040149479326 38.1605621082622 4.84898909388084 2.09399209486801e-06 -211.103199821439 98.4149750590217 -2.14503127897798 0.0328393073398152 ZNF746 other 2.25303129156879e-05 1 0.0226884043478949 4.84898909388084 -2.14503127897798 8.15308025071809e-09 2100.05372411062 365.3850205545 5.74750908212827 2.41732943523206e-08 -913.012556399437 1063.6433262633 -0.858382254516613 0.39143443121934 POLR2A essential 8.35283071686068e-05 1 0.000294503245094322 5.74750908212827 -0.858382254516613 0.000223758939747502 38.6035005864056 11.5021687611978 3.35619320041916 0.000902876403568422 -10.2883381775535 20.8124289837619 -0.494336253859679 0.621467724768388 TMEM136 other 1 1 1 3.35619320041916 -0.494336253859679 9.76943841512966e-11 166.432332274559 31.5540532733731 5.27451515761379 2.71236980796148e-07 -78.2964299043637 50.2606918728452 -1.5578064484756 0.120437615266292 FRAT2 other 1.11225056356251e-06 1 0.0031265486776372 5.27451515761379 -1.5578064484756 6.83007070972041e-11 70.6834800112347 11.0684424671559 6.38603671844332 7.33230620587995e-10 -39.7561518896488 32.2199519528179 -1.23389854671003 0.218305800097151 TMEM102 other 7.82726103333959e-07 1 9.51879991647336e-06 6.38603671844332 -1.23389854671003 0.565218914181847 125.151476268971 154.31929614552 0.810990455470684 0.418082813440629 -89.5895741611158 268.966748942234 -0.333087917050881 0.739325464114442 ZNF322 other 1 1 1 0.810990455470684 -0.333087917050881 0.270439766228358 1.25663626981576 1.28267573869693 0.979699102356435 0.328114939395237 -7.59535461112897 6.62252843251105 -1.14689648954048 0.25244349076063 NME9 other 1 1 1 0.979699102356435 -1.14689648954048 0.0717052579325984 70.5678920976317 46.4720818367123 1.51850077097007 0.130066972111397 -53.5195876199683 82.7259339366413 -0.646950539850759 0.518217664940723 HEPHL1 other 1 1 1 1.51850077097007 -0.646950539850759 3.14912198170538e-09 1333.18611509133 252.924985491636 5.27107320971029 2.75893963193247e-07 -891.96162017351 651.945339562564 -1.36815399397132 0.172388871100769 LRRC75A other 3.30531843199796e-05 1 0.00317774666805982 5.27107320971029 -1.36815399397132 0.496403650196396 -5.03004273657937 16.4410600927633 -0.305943942069367 0.759884849242766 28.0106661667035 32.0766244128657 0.873242327689212 0.383312760860384 CCL13 other 1 1 1 -0.305943942069367 0.873242327689212 0.553197980896053 3.53526572444509 19.0587942487436 0.185492622371856 0.852981935884378 -22.6718489882848 28.2774646617677 -0.801763851868166 0.423394633595171 CFAP65 other 1 1 1 0.185492622371856 -0.801763851868166 9.35930580905167e-08 71.161585512691 46.9578509579344 1.51543531190213 0.130836360209357 -244.200687521072 68.2445130336662 -3.57831973100319 0.000410051035454837 DDX60L other 0.000897744613204236 1 1 1.51543531190213 -3.57831973100319 0.000291872365530908 45.3819441593946 11.3035008872283 4.0148573979121 7.72717769546969e-05 7.40229230452899 44.7268528460443 0.165499958828059 0.868675256038201 SYNE4 other 1 1 0.733618250407892 4.0148573979121 0.165499958828059 2.43315627121216e-06 127.615389609507 29.0894543700755 4.38699839419421 1.66681374970473e-05 -63.9642082187288 63.3591268881197 -1.00955002633918 0.313642356329169 OGFOD3 other 0.0209689407453064 1 0.168031494107733 4.38699839419421 -1.00955002633918 0.360456754172108 8.53297049490663 14.7197365395167 0.57969587105034 0.562623634360753 -48.0622859961287 47.7994883350088 -1.00549791787054 0.315595613070444 WASHC1 other 1 1 1 0.57969587105034 -1.00549791787054 0.37746977142679 13.8636849130377 17.6241165982402 0.786631479413956 0.432205855743674 -32.7332584460349 39.3913327189467 -0.83097616116681 0.406740850923712 AATK other 1 1 1 0.786631479413956 -0.83097616116681 0.0135984646805521 24.9563628489111 8.66963457613458 2.87859455087184 0.0043117216134091 7.31229357589034 21.7519909816629 0.336166633300586 0.737004395420041 DDN other 1 1 1 2.87859455087184 0.336166633300586 0.0281807558540808 28.9937377311545 17.9689315130448 1.61354823519173 0.107815577674923 -62.5789394716114 46.3598239870663 -1.34985282707436 0.178215088447218 ZNF467 other 1 1 1 1.61354823519173 -1.34985282707436 1.87311497319784e-18 1183.97256551925 120.92525242226 9.79094557838853 1.9693724345517e-19 712.616230780414 1297.55264313328 0.549200245979705 0.583346757624859 SOX2 og 2.67668129669971e-14 1 3.00486846063898e-15 9.79094557838853 0.549200245979705 7.98595159197381e-07 33.9476488545702 8.23252217015362 4.12360248207345 4.95430030983538e-05 -68.2489315307457 22.815560276343 -2.99133270031995 0.00303137586442815 ZNF678 other 0.0071657943634781 1 0.478337694914606 4.12360248207345 -2.99133270031995 0.0822956581902021 286.477527605709 198.285664286447 1.44477175713449 0.149698940938002 -943.899206391959 733.753680561554 -1.28639791717239 0.1994227277533 TMEM45A other 1 1 1 1.44477175713449 -1.28639791717239 4.09158944140278e-10 524.1051297648 77.1629651484915 6.79218493944885 7.06508051948959e-11 -158.215797496557 494.144018819371 -0.320181549246659 0.749079267534039 RAP2B other 4.51793306119695e-06 1 9.48645259272039e-07 6.79218493944885 -0.320181549246659 0.000229254623003214 29.1974443412757 14.4376738604593 2.02230945396538 0.0441230103902536 -75.3144234193746 27.3983071379122 -2.74887141896292 0.00638046853284056 ZBTB2 other 1 1 1 2.02230945396538 -2.74887141896292 1.21437496921879e-06 60.2985103367268 24.1946741748668 2.49222245775743 0.0133084439603962 -148.805448878853 48.4465366478662 -3.07153945720509 0.00235212179244615 RNF135 other 0.0107447897276478 1 1 2.49222245775743 -3.07153945720509 0.00167274740227146 25.8598342478315 9.60196355289091 2.69318187945483 0.00751532529945779 -24.6513396689057 20.1734089366695 -1.22197194070144 0.222772292035354 ACBD4 other 1 1 1 2.69318187945483 -1.22197194070144 6.99456695462677e-06 168.908251121878 34.1165024577476 4.95092518147386 1.30285459532523e-06 70.308669797302 76.7794581572222 0.915722401339824 0.360629638620925 SGSH other 0.0580059437547198 1 0.0143314005485775 4.95092518147386 0.915722401339824 2.35364581057529e-07 316.815072822389 64.6028870199048 4.90403892824133 1.61735525881758e-06 -218.678532524648 167.26208714499 -1.30740047704348 0.192180786174639 SETD2 other 0.00219971737456367 1 0.0176776929788762 4.90403892824133 -1.30740047704348 1.15337573022988e-07 202.603962807412 36.3856758816751 5.56823414428999 6.21005565909167e-08 19.2191829754058 88.4664227977808 0.217248334086454 0.828178894254428 C6orf223 other 0.00110032044663931 1 0.000742101651261454 5.56823414428999 0.217248334086454 0.490230770906193 -2.18689039809261 3.64582097213766 -0.59983482864502 0.54911385320974 -11.1460154613105 9.47601792891126 -1.17623410433871 0.240525986953942 TMIE other 1 1 1 -0.59983482864502 -1.17623410433871 0.000266551751139433 16.9743535979466 42.6221515102252 0.398251918227883 0.690760399079056 -241.297520421502 74.9832073455182 -3.21802079377076 0.00144890321128843 MEX3D other 1 1 1 0.398251918227883 -3.21802079377076 2.2598908553061e-11 341.051811248807 50.7201350451077 6.72418973146453 1.03644230685767e-10 -102.715164625651 109.206579024854 -0.940558394401077 0.347765748884358 MRPS23 essential 2.64316834436601e-07 1 1.38437598926979e-06 6.72418973146453 -0.940558394401077 0.500308479276026 -1107.89867165888 1398.52314452338 -0.792191874691108 0.428939160093477 -3317.35176170288 2871.05091430999 -1.15544860077835 0.248920744025425 FDCSP other 1 1 1 -0.792191874691108 -1.15544860077835 1.66771951967167e-06 12.0665790524709 2.79673196460627 4.31452824409993 2.24069531373976e-05 -2.5028609999816 5.18518661903615 -0.482694487946288 0.629700923115643 GPR135 other 0.0145958812361664 1 0.223531764498678 4.31452824409993 -0.482694487946288 0.660675670867384 -1.05807987702445 4.68954250352237 -0.22562539442381 0.821665393736801 -27.8708148080504 31.1526681440948 -0.894652576117578 0.37177861000348 P2RY13 other 1 1 1 -0.22562539442381 -0.894652576117578 0.725931577655292 13.8489777172055 17.7317625748544 0.781026570750777 0.435468595769763 5.8823108009277 32.9687476217776 0.178420814415229 0.858525809384693 TNFSF15 other 1 1 1 0.781026570750777 0.178420814415229 1.05529444364174e-08 53.9730767031799 9.57907464102731 5.63447709990822 4.4096984125722e-08 -43.6824468810794 35.7375845816512 -1.22231111566245 0.222655959635387 ZFP41 other 0.000107376209640547 1 0.00053105997982607 5.63447709990822 -1.22231111566245 0.553372384583857 3.17209902953842 51.5082997292416 0.0615842310115626 0.950939162173142 -57.0962896173248 74.4050146196617 -0.767371526088471 0.443526244174376 PHLDA2 other 1 1 1 0.0615842310115626 -0.767371526088471 0.278812616318666 44.5885107898721 27.8463215275091 1.60123522045178 0.11048130906208 43.1589076553177 70.2355369589416 0.614488185383243 0.539404557198922 ATG9B other 1 1 1 1.60123522045178 0.614488185383243 8.51495697920447e-17 195.393784837542 21.7329909726943 8.99065320015262 4.48972039175381e-17 -7.28135655661817 106.948648414871 -0.0680827356356355 0.945770351617853 HKR1 other 1.17761855022398e-12 1 6.72425423072968e-13 8.99065320015262 -0.0680827356356355 0.0011166529284316 54.3949250670745 19.6094667313274 2.77391148940195 0.00594007993717017 -85.8792416456389 60.4360658874231 -1.4209932493887 0.156516934891773 PLAG1 other 1 1 1 2.77391148940195 -1.4209932493887 0.216934502956054 34.1573921153361 27.949083268367 1.22212924793837 0.222720675713262 -106.400143133788 105.820414202271 -1.00547842243755 0.315563461724037 ZBTB20 other 1 1 1 1.22212924793837 -1.00547842243755 0.000537210958912894 408.598384491113 105.118696057643 3.88701914897283 0.000127780781152812 -46.2651743224498 579.72404344565 -0.0798055123735561 0.936451058177378 C3orf58 other 1 1 1 3.88701914897283 -0.0798055123735561 1.42483110595758e-09 91.1389756470462 21.5648873899844 4.22626717213347 3.242933200624e-05 -88.896134105056 35.5551636017183 -2.50023133350903 0.0129980656686529 C5orf30 other 1.52699149625474e-05 1 0.318618186961308 4.22626717213347 -2.50023133350903 0.220663529138808 41.1428270708346 31.7644824849482 1.29524625783941 0.196329516371547 -4.6392221871383 47.2941775795758 -0.0980928821382395 0.921930521394005 AMIGO1 other 1 1 1 1.29524625783941 -0.0980928821382395 0.0278354382278373 24.4848484848485 9.33064535614892 2.62413236708358 0.00917968535553205 27.0467385721622 13.5540896160636 1.99546700208532 0.0469929523821765 GPR3 other 1 1 1 2.62413236708358 1.99546700208532 5.02826309036148e-16 450.854664652661 50.7736982587933 8.8796892902041 9.43676493964758e-17 552.901949639503 333.312346065267 1.65881029060723 0.0983108963991578 SIAH2 other 6.82335301362053e-12 1 1.40956957903516e-12 8.8796892902041 1.65881029060723 4.01118452396223e-13 1004.35341800854 132.927768332691 7.55563288698902 6.43055941934088e-13 -601.494011438754 507.687236162878 -1.18477276676261 0.237145274970156 COPG1 essential 5.01398065495279e-09 1 9.09731241054155e-09 7.55563288698902 -1.18477276676261 0.00014930250073751 263.815371670592 62.728389813593 4.2056774046737 3.54058043716994e-05 93.9293009474316 234.192505457418 0.401077313571464 0.688679255726329 ADGRB1 other 1 1 0.347012288647025 4.2056774046737 0.401077313571464 0.0314326507616416 46.4585049904438 17.6311690134648 2.63502124873079 0.00890123352302836 59.0452815957704 97.3100218628273 0.606774928886599 0.544512053844986 SLC9A9 other 1 1 1 2.63502124873079 0.606774928886599 8.03327876367188e-10 30.951115265829 31.012270778811 0.99802802208783 0.319152797461 -229.311423635353 44.2612456975308 -5.18086240053894 4.30737455187018e-07 LSM10 essential 8.72976403248223e-06 0.0067720542704503 1 0.99802802208783 -5.18086240053894 2.04741783426055e-06 43.8763873456979 14.8228260471589 2.96005547161552 0.00334797784036158 -36.7430129058253 23.7894008879612 -1.54451190590594 0.123631287049912 RELL1 other 0.0177777290548843 1 1 2.96005547161552 -1.54451190590594 2.22084803644021e-13 267.552601688723 38.4005430459468 6.96741713700747 2.48262615216919e-11 -67.1885183080298 74.8221237088311 -0.897976627467735 0.370001027656577 RFX7 other 2.80026728914747e-09 1 3.37661982956531e-07 6.96741713700747 -0.897976627467735 4.14049234709871e-06 68.1475718948479 39.0452999558578 1.74534635338674 0.0820880558338612 -288.572378023353 83.8079921757667 -3.44325607297862 0.000668214917590224 SLC35C1 other 0.0350534082105377 1 1 1.74534635338674 -3.44325607297862 0.76577169280855 -7.61679627527682 10.7358526575236 -0.709472877306959 0.478641032602566 -12.544027841618 40.4676820337596 -0.309976435792722 0.756817109183312 TIGIT other 1 1 1 -0.709472877306959 -0.309976435792722 1.42620658889549e-08 217.330801112945 41.4972240454795 5.23723709505864 3.2678897643571e-07 -156.44942967316 110.468984966752 -1.41622944865698 0.157852481572699 RNF41 other 0.000143804410358333 1 0.0037446748809768 5.23723709505864 -1.41622944865698 0.342317708768102 -1.58087323809788 4.38111444472417 -0.360838151580724 0.718501555287298 16.6807001667346 13.1078802813789 1.27257037817406 0.204261267029685 SLC2A4 other 1 1 1 -0.360838151580724 1.27257037817406 0.000962938259477718 48.2378715880207 14.893424328619 3.23887042520689 0.00134846740266009 -62.9938667256051 41.7159379024382 -1.5100671324454 0.132182825955723 IBA57 other 1 1 1 3.23887042520689 -1.5100671324454 0.18684767783353 251.418062392821 164.650551491736 1.52697977695774 0.127932298870725 -282.425820900847 492.618886004145 -0.573315049270098 0.566906827883283 CLDN7 other 1 1 1 1.52697977695774 -0.573315049270098 0.0202775737768448 29.8468647880531 12.6661867628212 2.35642070869049 0.0191747988081534 -16.4496714221955 30.572638148069 -0.538052075929027 0.590989314376472 ZNF329 other 1 1 1 2.35642070869049 -0.538052075929027 1.72930727773362e-16 64.949581634842 10.0561681448266 6.45868095078097 4.89447658157147e-10 -67.6747880668285 23.2428989584785 -2.91163284699227 0.00389563551453867 ZNF101 other 2.37226372359498e-12 1 6.39120752021603e-06 6.45868095078097 -2.91163284699227 1.92462508744929e-08 189.14787415466 57.274739828331 3.30246588149664 0.00108619101766633 -270.152585374049 93.1637377642347 -2.89976112870989 0.00403810129654759 C5orf24 other 0.000192731956257171 1 1 3.30246588149664 -2.89976112870989 1.82151325653821e-07 121.579149018962 35.9890105794661 3.37822982797783 0.000837467517031562 -91.650208779203 54.0580470176191 -1.69540362324468 0.091155966253621 ADO other 0.00171477257970507 1 1 3.37822982797783 -1.69540362324468 4.50254011300638e-24 396.002050623099 39.3579559117475 10.061550236782 2.02101175812813e-20 -198.858624643439 106.869256691449 -1.86076548859678 0.0638683169970872 COA4 other 6.85781884612002e-20 1 3.09982783461693e-16 10.061550236782 -1.86076548859678 7.25867407386813e-10 250.081122181906 49.1739096017859 5.08564651879588 6.83219277201526e-07 -304.77984250507 123.376646247074 -2.47032037079949 0.0141128636429192 PRKAG1 other 7.90324433162762e-06 1 0.0076602545359835 5.08564651879588 -2.47032037079949 3.08814717465176e-07 114.13904323079 27.2591040967628 4.18718982199949 3.81427414174894e-05 -27.6703106413092 47.7214572718748 -0.579829540486748 0.562507783829956 GINS3 essential 0.00286703583694669 1 0.372463869941784 4.18718982199949 -0.579829540486748 1.64110276629414e-16 4.42079013770801 22.365256593221 0.1976632872188 0.843458914765846 -217.636672068432 32.2172807413817 -6.75527751132908 8.89467673623834e-11 CCDC149 other 2.25257765701534e-12 1.41798936529112e-06 1 0.1976632872188 -6.75527751132908 1.35060550829439e-10 148.687253042158 26.5279153922641 5.60493543663508 5.12307471406489e-08 -122.970049167108 53.5704712296606 -2.29548193891979 0.022469467552172 MRPS11 essential 1.52564398216935e-06 1 0.000615102657702261 5.60493543663508 -2.29548193891979 2.19752473146258e-14 222.212115442157 27.6507700413377 8.03638072682791 2.83835004412313e-14 -143.628031807343 81.3927171957376 -1.76463001550788 0.0787482555260856 SNRPE essential 2.85634264595506e-10 1 4.10737634885058e-10 8.03638072682791 -1.76463001550788 0.638089430980981 -61.0381011971851 198.074577058051 -0.308157170414133 0.758201225120929 -268.799216228942 297.522066519617 -0.903459764760738 0.36709026646775 RTKN2 other 1 1 1 -0.308157170414133 -0.903459764760738 0.000104511189391817 42.5962482163378 120.793372288393 0.35263729631324 0.724633470803641 -572.249517975845 168.601882001129 -3.39408736832496 0.000791137519497661 CHST15 other 0.772755734363092 1 1 0.35263729631324 -3.39408736832496 0.0524535591538478 10.5083147193311 16.628016411597 0.631964418317644 0.527938987265009 -79.9519712905921 37.4937851717299 -2.13240596873306 0.0338659130461064 USH1G other 1 1 1 0.631964418317644 -2.13240596873306 0.524989830410536 8.23393188056332 10.598790918985 0.776874640088839 0.437920447713253 -14.9609456210538 24.9834788172022 -0.598833562392142 0.549791593645455 MGAT4C other 1 1 1 0.776874640088839 -0.598833562392142 1.57303439021914e-09 1231.12406996615 189.838010829985 6.48512942473211 4.16262623526798e-10 308.275744296964 456.556166990724 0.675219757360602 0.500109739519847 IDH2 other 1.68173106658328e-05 1 5.45304036820106e-06 6.48512942473211 0.675219757360602 2.15824121079619e-09 7.71661195408481 1.42456846724092 5.4168066551622 1.33935317783735e-07 -4.4651277759227 3.20040929568987 -1.39517398038309 0.16410567792764 OGFRP1 other 2.29118886938123e-05 1 0.00157266850141662 5.4168066551622 -1.39517398038309 6.69728133380072e-09 159.101139270771 150.650621607435 1.05609348022045 0.291866067226453 -1241.98925422174 265.15285507119 -4.68405008834726 4.45416426580437e-06 TMEM259 other 6.8961905894146e-05 0.0690217294629046 1 1.05609348022045 -4.68405008834726 2.77450533548189e-15 141.651947712978 23.6302876747139 5.99450796633999 6.4650206995929e-09 -99.7735253614657 38.1166854631926 -2.61758135968596 0.00935139298087691 WRB essential 3.69536365632832e-11 1 8.0896804014006e-05 5.99450796633999 -2.61758135968596 8.88017552003582e-07 856.333428943086 168.328383220194 5.08727888048979 6.80831282430416e-07 -307.04652682289 425.497614100545 -0.721617505357703 0.471154109515267 TNRC18 other 0.00793798889736002 1 0.00763416116989225 5.08727888048979 -0.721617505357703 0.00153765056414573 15.0801854171887 9.89310395559892 1.52431284305409 0.128596686840571 -49.5183212227512 21.4316230287784 -2.31052595299283 0.0216102059306834 FAM181B other 1 1 1 1.52431284305409 -2.31052595299283 1.34337226109272e-06 329.609408571127 100.076459608781 3.29357583051637 0.00112025603994583 -345.348528446701 179.069757025137 -1.92856981650018 0.0548248713965816 TMEM30B other 0.0118485433428378 1 1 3.29357583051637 -1.92856981650018 3.71094262297821e-18 103.668654579454 18.1542646153863 5.71042985082369 2.97707934337805e-08 -141.413495980522 35.2773256915475 -4.00862291027931 7.91470452611853e-05 DEXI other 5.27065180741595e-14 1 0.000361149495145191 5.71042985082369 -4.00862291027931 1.52777447058531e-07 253.643557823182 94.650070528053 2.67980315712502 0.00782264410345765 -507.597817014204 168.59010618368 -3.01083989152466 0.0028538280233197 NOP10 essential 0.00144512187172664 1 1 2.67980315712502 -3.01083989152466 3.10539359887378e-16 175.332102853053 19.4576092055366 9.01097873849592 4.09244232206458e-17 -27.3021200358561 76.227452312951 -0.358166503109241 0.720502778545239 TDRKH other 4.23699902630339e-12 1 6.13211557538157e-13 9.01097873849592 -0.358166503109241 2.99653626354573e-05 25.360824914531 7.46912971416876 3.39541899592694 0.000789048319379801 -22.1574526946497 16.6996927923824 -1.32681798223001 0.185698281340506 ZNF708 other 0.234688720160902 1 1 3.39541899592694 -1.32681798223001 1.58192872147963e-22 387.320718285382 77.8958716194297 4.97228813585509 1.180326305453e-06 -740.428778308006 133.636797099277 -5.54060553964002 7.17838026500919e-08 IST1 other 2.37874621848892e-18 0.00113547619031915 0.0130213598017575 4.97228813585509 -5.54060553964002 4.16004401234657e-20 81.3801581301581 11.7842638782987 6.90583297952309 3.56910643648966e-11 -93.0322035322034 22.6823367903535 -4.1015264164391 5.43727165706504e-05 ERCC6L2 other 6.08905642087167e-16 0.819723075019126 4.83292702565065e-07 6.90583297952309 -4.1015264164391 9.96989946121882e-09 113.514786850287 36.3892285574347 3.11946120734936 0.00201033426110706 -264.027994239949 68.5720256173397 -3.85037472442968 0.000147681018830912 MRPL41 essential 0.000101653094906587 1 1 3.11946120734936 -3.85037472442968 0.0934725307931331 67.9352361448865 80.252172743703 0.846522079369085 0.39800298521869 -340.954067532271 220.864723757579 -1.54372351424713 0.123813684980346 CREB3L2 og 1 1 1 0.846522079369085 -1.54372351424713 7.25884171827681e-06 59.2209638328485 19.4851547197338 3.03928630204162 0.00261323628232076 -191.063831167116 67.0894861097409 -2.84789528503148 0.0047525507235175 TP53TG1 other 0.0601104682690502 1 1 3.03928630204162 -2.84789528503148 0.0526291669711248 -37.723982653896 20.8506640190896 -1.80924610455371 0.0715248834514952 -73.8985296353409 30.6501245109309 -2.41103521811098 0.0165754773156995 UNC5C other 1 1 1 -1.80924610455371 -2.41103521811098 2.11938787256896e-11 209.485895906226 29.615082810344 7.07362181790207 1.28749694782746e-11 -11.0257520302256 68.5863333115791 -0.160757274778592 0.872404346589019 TSEN54 essential 2.4820151375655e-07 1 1.7663170627245e-07 7.07362181790207 -0.160757274778592 7.53082328206008e-06 672.327952970974 155.851211076504 4.31390906959935 2.25195401679473e-05 -402.922064921291 384.449796183021 -1.04804858507319 0.295553476251425 RGMA other 0.0622949701892009 1 0.224609893635106 4.31390906959935 -1.04804858507319 2.79486860844861e-21 741.119543434887 97.5502407380957 7.59731127086253 4.97894294621888e-13 -167.743927821 152.61737438203 -1.09911422929545 0.27269732583124 MRPS16 essential 4.15205680471126e-17 1 7.06362635780072e-09 7.59731127086253 -1.09911422929545 0.00526303422372655 -1.59959958252619 1.89904732982926 -0.842316859301242 0.400353357305876 -10.533600955154 3.36531553843462 -3.13004853032407 0.00193881694613092 FAM159A other 1 1 1 -0.842316859301242 -3.13004853032407 6.40866289455874e-19 52.4325648281212 6.35872876429164 8.24576212820459 7.0657653119004e-15 -9.95229375296243 11.5967386190545 -0.858197643310672 0.391538930821095 RAD51B other 9.22911543445405e-15 1 1.03188436614993e-10 8.24576212820459 -0.858197643310672 2.186066965291e-07 435.965018026819 88.2391443093022 4.94072128010039 1.36161051213237e-06 -239.517743143869 183.018671327282 -1.30870660029847 0.191738414520552 ARL6IP4 other 0.00204812613978114 1 0.0149640995283348 4.94072128010039 -1.30870660029847 1.63085817268283e-06 457.987491027937 88.9811721754302 5.14701570940193 5.07871494201595e-07 -128.341306241846 362.318284097169 -0.354222549275009 0.723446550648478 EXT1 ts 0.0142830558763562 1 0.00573844001298382 5.14701570940193 -0.354222549275009 1.9576026468376e-13 1407.80675055649 189.139297151376 7.4432271440121 1.28622351952007e-12 -245.639474401491 506.54891794959 -0.484927448657458 0.628116684700029 SHMT2 other 2.47303942374993e-09 1 1.80778715668546e-08 7.4432271440121 -0.484927448657458 1.95550399476196e-09 -3.85961178872929 32.5494642786431 -0.118576814527228 0.905697836997348 -239.001671660785 48.6057841267373 -4.9171446558212 1.51817041575638e-06 MOB2 other 2.08065625042672e-05 0.0236925675082941 1 -0.118576814527228 -4.9171446558212 0.956321742651201 -3.10807881099586 15.4907674884811 -0.200640724438412 0.841131125261118 -9.76381644263395 34.0279614795042 -0.286935097434941 0.774382906996875 HHIPL1 other 1 1 1 -0.200640724438412 -0.286935097434941 7.11468130494864e-17 151.491607743917 17.1886973616426 8.81344319215127 1.45137154462545e-16 -10.2827538949252 50.7116088798595 -0.202769230203009 0.83946644644776 CYB5D1 other 9.85739094800634e-13 1 2.16443038449994e-12 8.81344319215127 -0.202769230203009 0.00169054465714862 35.275677529696 174.437019668045 0.202225866945135 0.839893007955393 -755.532048752065 253.788460912205 -2.9770149755289 0.00317581785278078 BACE2 other 1 1 1 0.202225866945135 -2.9770149755289 0.000646025272694246 106.152790277092 28.8171094513845 3.68367238414997 0.000277706079041396 8.09555651535109 76.3891374782869 0.105977849503173 0.915678620349349 UBE2E2 other 1 1 1 3.68367238414997 0.105977849503173 0.777248802740463 22.4048732862202 31.5860997718804 0.709326996622932 0.478726924220835 22.4602896591974 121.927994081974 0.184209457625433 0.853985897048505 SYNM other 1 1 1 0.709326996622932 0.184209457625433 0.299643704783573 23.5624100564288 15.159470658651 1.55430295601928 0.121310121043773 23.1431308963008 28.9591367755279 0.799165081324455 0.424913105916246 KCNA4 other 1 1 1 1.55430295601928 0.799165081324455 0.0360729295501131 39.5840518406525 19.3503362242418 2.04565188852183 0.0417524663150737 -9.15688005324265 36.2028470004192 -0.2529325954154 0.800511349892274 GABRG3 other 1 1 1 2.04565188852183 -0.2529325954154 2.4476851619022e-10 8.19404725546268 1.59574938949409 5.13492112822332 5.40987160719019e-07 -7.99168448232779 3.56772742782701 -2.23999300506969 0.0259052454528514 PRR34 other 2.73308525177999e-06 1 0.00610395813439269 5.13492112822332 -2.23999300506969 0.488787977728982 5.56298668740474 9.65609889668853 0.576111196345816 0.565023507904606 -17.726764353761 23.8516566906784 -0.74320893444223 0.458006197996582 FIGN other 1 1 1 0.576111196345816 -0.74320893444223 0.000203499555682988 159.411054457229 95.0640524932607 1.6768804850659 0.0947189160899163 -252.508406467387 152.143383044772 -1.65967393003927 0.0981367684036754 B4GALNT4 other 1 1 1 1.6768804850659 -1.65967393003927 5.52423372817743e-15 390.476969410651 48.331828730851 8.0790853494315 2.55153155410582e-14 -144.855864658157 180.549490975828 -0.80230558322399 0.423117480018113 C8orf33 other 7.29972244841366e-11 1 3.69512799665605e-10 8.0790853494315 -0.80230558322399 0.0131711815370047 1.36234085348152 1.26196310201563 1.07954095591668 0.28131005195487 -2.56560257952141 1.85302185706693 -1.38455062995447 0.167333048497478 DCAF4L1 other 1 1 1 1.07954095591668 -1.38455062995447 0.167801418051218 6.64301921831091 7.14798236372173 0.929355849005214 0.353525709267261 -19.5369013017937 16.5331590619355 -1.1816798730724 0.238361060273229 SPACA6 other 1 1 1 0.929355849005214 -1.1816798730724 3.7771138677204e-17 23.3238260077003 3.83227853274331 6.08615104784779 4.01862563540606e-09 -39.9001514980676 9.26174461975123 -4.30805999692306 2.31961524715664e-05 ZSCAN22 other 5.26756299992287e-13 0.353602148276558 5.07552417751785e-05 6.08615104784779 -4.30805999692306 0.000291251862957504 16.6798797801795 5.671336399311 2.94108453559656 0.00355102143106866 -16.3412869337082 11.8086368007812 -1.38384194631399 0.167537206119449 KCNJ14 other 1 1 1 2.94108453559656 -1.38384194631399 1.44701110440223e-08 179.565797492062 29.8052604876516 6.02463439520875 5.57630793553181e-09 10.3548089655418 112.801808477313 0.0917964800859061 0.926928318149096 FBXL6 other 0.000145844249212701 1 6.99715119750531e-05 6.02463439520875 0.0917964800859061 0.0267435693399731 1194.13931917324 464.5809997063 2.57035763392854 0.0106959304816327 2825.75456639954 2170.94947663014 1.30162152404662 0.194155269905558 C1S other 1 1 1 2.57035763392854 1.30162152404662 0.659506205478523 -0.661973812940713 4.33994654144348 -0.152530407141959 0.878883380315054 -8.96009443095564 9.89249004781272 -0.905747126117833 0.365883280450155 KIAA2012 other 1 1 1 -0.152530407141959 -0.905747126117833 4.04334332713022e-32 148.728863117995 10.7619588660588 13.819869130615 3.05082774268305e-33 110.822924614525 23.7386331751803 4.66846274579931 4.77847358805852e-06 KBTBD3 other 6.36058338790854e-28 0.0739994419846742 4.82854506834446e-29 13.819869130615 4.66846274579931 5.44971514544744e-07 50.8124863048717 11.7473638417002 4.32543734829259 2.14721377430634e-05 -12.948745573079 17.8767301726348 -0.724335236255932 0.469489451838367 YBEY other 0.00495924078235717 1 0.21448518391546 4.32543734829259 -0.724335236255932 1.27276045374581e-05 389.045075637124 84.1875812986899 4.62116941282382 5.88966905086567e-06 35.3859793076818 225.46942308617 0.156943583849762 0.875405315515728 NXPH4 other 0.103271783216935 1 0.0615764899268006 4.62116941282382 0.156943583849762 2.03327241952795e-06 60.3185868902718 14.2044351031401 4.246461506726 2.99417137303741e-05 -44.1356567863735 32.787150258625 -1.34612665139335 0.179394969303489 CACNB4 other 0.0176650707808588 1 0.295644481373713 4.246461506726 -1.34612665139335 2.07349667234659e-24 163.935081662426 21.0804086967282 7.77665575752663 1.74717416611306e-13 -122.383190366004 39.3812350287884 -3.10765242066531 0.00209509137674139 TRAPPC6B other 3.16436327166814e-20 1 2.49810962270846e-09 7.77665575752663 -3.10765242066531 2.18495265824143e-06 14.7387997207001 5.62611744883322 2.61971063610781 0.00930212925196966 -25.7146985100063 10.0212002837895 -2.56602979501397 0.0108310901964914 PGBD4 other 0.018915135162396 1 1 2.61971063610781 -2.56602979501397 2.4749808823892e-13 760.197568909998 106.427366699144 7.14287680403647 8.56117453715111e-12 -221.41547216079 236.749800520956 -0.93522981507725 0.350508666570933 NPLOC4 essential 3.11674342519272e-09 1 1.18037977798108e-07 7.14287680403647 -0.93522981507725 0.0809994590876539 5.8371001464562 28.7975540993858 0.202694302658874 0.839526069742453 -187.122210559519 88.9431965098991 -2.10383950546114 0.0363139151174219 TSHZ2 other 1 1 1 0.202694302658874 -2.10383950546114 5.41119502456589e-08 251.683031005086 51.7014087205626 4.86801108970531 1.9351242439928e-06 -514.728097834026 219.313123405797 -2.34700089917383 0.0196589091340065 CAPN12 other 0.000527050395392718 1 0.0210367356564458 4.86801108970531 -2.34700089917383 6.53841513791555e-11 620.107583558174 92.020682732623 6.7387848594861 9.56713431570642e-11 -145.496827707466 210.921907520295 -0.689813729725853 0.490901607370316 EXOC7 essential 7.50021600470293e-07 1 1.27969988606889e-06 6.7387848594861 -0.689813729725853 7.19301851846543e-12 1185.25759968548 165.360848401262 7.16770391023485 7.35371130283608e-12 -171.407419121854 371.692001885152 -0.46115444575753 0.645060444926486 KPNA2 other 8.57551667771449e-08 1 1.01473862267835e-07 7.16770391023485 -0.46115444575753 0.171519562147117 -17.7841580134154 9.44041426202655 -1.88383237427949 0.0606661453751878 -19.939881585726 31.7452393170362 -0.628121948824787 0.530456954643006 NCF1B other 1 1 1 -1.88383237427949 -0.628121948824787 3.95751805988206e-17 135.473245419586 15.4264134731504 8.78190161668983 2.06938070836835e-16 -44.4080067937946 57.6509033459027 -0.770291603712584 0.441815686028561 CEP97 other 5.5163844236696e-13 1 3.08192868897298e-12 8.78190161668983 -0.770291603712584 0.562004019486418 20.4483247804203 21.4578026515079 0.952955207600598 0.341465099695676 -10.4151276122805 51.6293942585307 -0.201728642411094 0.840280771130578 FES other 1 1 1 0.952955207600598 -0.201728642411094 1.17365148904586e-29 367.067891955261 32.9181848127441 11.1509153388419 5.29900509916484e-24 -115.12207820039 73.4534798829105 -1.56727875090331 0.118220759660897 GLRX5 essential 1.83652985005896e-25 1 8.25479014347899e-20 11.1509153388419 -1.56727875090331 0.00337689151003908 342.881086770745 122.574007392073 2.79733928967487 0.00552047294025102 -301.884436292391 270.534608384052 -1.11588102570535 0.265457911921319 MXRA7 other 1 1 1 2.79733928967487 -1.11588102570535 6.38039394829849e-11 380.55451849487 97.8733803910954 3.88823311276467 0.000127072919413041 -1424.45366831047 311.988643831395 -4.56572281227092 7.55949948437343e-06 LIMK2 other 7.32341617385701e-07 0.116612839045944 1 3.88823311276467 -4.56572281227092 3.13708729705974e-06 55.0124738433618 28.942678833274 1.90073884177289 0.0583894113048381 -300.786496905978 77.9102004522182 -3.86068185115823 0.000141221705445675 MFSD5 other 0.0267875884295931 1 1 1.90073884177289 -3.86068185115823 0.0393311177028674 4.47142451684194 3.41855373030147 1.30798719856529 0.191981975860828 -9.40819952746947 7.32169449909459 -1.28497570181778 0.199893910955778 RNASE10 other 1 1 1 1.30798719856529 -1.28497570181778 0.0109927115167837 569.853162759698 209.039624147591 2.72605332641317 0.00683377873432546 -194.181725545567 611.69221690373 -0.317450051152323 0.751150241121207 ADI1 other 1 1 1 2.72605332641317 -0.317450051152323 7.01307926963077e-20 77.6979653461785 14.3823684708753 5.40230668568388 1.44478026281751e-07 -71.4572339252766 21.5145142728599 -3.32135009040936 0.00101937928327923 RWDD4 other 1.02348878860991e-15 1 0.00169241559986443 5.40230668568388 -3.32135009040936 0.00436105296490173 -4.31918829536418 1.29973493328218 -3.32313011273542 0.00101268125587055 -4.47902031364866 3.88367672347882 -1.15329380701815 0.24980598656141 SPNS3 other 1 1 1 -3.32313011273542 -1.15329380701815 0.789561179472531 -23.0311129994785 39.8632382125398 -0.57775318895778 0.563910488026501 -59.1915158655053 107.005139154015 -0.553165168827167 0.580606351477961 SATB1 other 1 1 1 -0.57775318895778 -0.553165168827167 0.746463513379526 0.582083806127389 13.4053267313507 0.0434218290827693 0.965397371530325 -21.2901209194976 29.9313862302602 -0.711297524134503 0.477513934279924 NXPH3 other 1 1 1 0.0434218290827693 -0.711297524134503 0.512263626878294 -144.308868936179 146.638432647662 -0.984113552842722 0.325931042774607 -245.116336172676 244.70731337026 -1.00167147763907 0.317389292066859 CSF1R other 1 1 1 -0.984113552842722 -1.00167147763907 2.34957557024298e-16 467.419103875364 51.4742832567011 9.08063355723393 2.38847602342454e-17 87.834853202877 549.413511707087 0.159870209471122 0.87310329342753 EPHB3 other 3.2142193800924e-12 1 3.58772983478601e-13 9.08063355723393 0.159870209471122 0.0424534436413144 2.83427841016137 2.07838479353527 1.36369281519827 0.173808591017797 -18.5826206946323 10.4341056506333 -1.78095002263126 0.0760532101756193 ACTL10 other 1 1 1 1.36369281519827 -1.78095002263126 0.0664641378785212 22.2889484877742 11.032012986187 2.02038816630127 0.044337771816759 0.598094422545256 21.9317072468627 0.0272707644604737 0.978264070299344 EPGN other 1 1 1 2.02038816630127 0.0272707644604737 0.683044577274374 -5.87179043883461 18.693073814064 -0.314115832272427 0.753672966663369 -24.5150246729902 28.5827895141491 -0.85768481977082 0.391818852856337 C2orf82 other 1 1 1 -0.314115832272427 -0.85768481977082 0.82521437124508 -3.43348992443879 10.5683774944441 -0.324883353782906 0.745522816279466 -12.7321888754064 20.5485143983227 -0.619616028127349 0.536037028032135 HS3ST4 other 1 1 1 -0.324883353782906 -0.619616028127349 8.03400074162049e-05 271.660476752731 111.095330175085 2.44529159168613 0.0151079823212095 -738.888441182062 286.448618627131 -2.57947985479333 0.0104203279987409 TRAK1 other 0.602148355584456 1 1 2.44529159168613 -2.57947985479333 0.0584473832891122 11.1563926526765 8.51289438317435 1.3105287285987 0.191134852636557 44.3139289987244 18.937103393433 2.34005845973738 0.0200121487271406 TSPAN10 other 1 1 1 1.3105287285987 2.34005845973738 6.60175682696475e-08 150.469949074515 26.0233054356636 5.78212285316773 2.08553652369103e-08 12.7764725459568 97.3267701317165 0.1312739807215 0.895658936505768 PLCB1 other 0.000639446166259806 1 0.000254831707829807 5.78212285316773 0.1312739807215 6.65240511360025e-10 237.396965261155 38.2277785989014 6.21006435534754 1.97398211474759e-09 -69.1137738139554 81.4702527407229 -0.848331403044843 0.396999357357979 SKA2 other 7.26243066251739e-06 1 2.52314393907037e-05 6.21006435534754 -0.848331403044843 0.00566924070845067 38.231125761087 11.9430975889652 3.20110636928988 0.00176290863740009 26.2487009341759 19.6545791927205 1.33550053027325 0.184304892750443 CCNYL2 other 1 1 1 3.20110636928988 1.33550053027325 1.00930267665128e-05 205.19208077944 45.1574756286098 4.54392274862768 8.3726134321738e-06 52.5441917625623 93.8668281869788 0.559773806971473 0.576103032554609 NDN other 0.0826517961909733 1 0.0864974693677876 4.54392274862768 0.559773806971473 0.691757255467685 -33.3317548170609 52.117562581732 -0.63954937963166 0.523016004812166 -77.564634926814 94.7221025948397 -0.818865215213662 0.413596330138903 NTM other 1 1 1 -0.63954937963166 -0.818865215213662 1.44257898617036e-11 589.701913623568 150.165379488462 3.92701643769281 0.000109076907651498 -877.226919836631 239.283957214144 -3.66604986832263 0.000296174997801503 TTC3 other 1.70195468788379e-07 1 1 3.92701643769281 -3.66604986832263 0.322684459664865 7.885379180435 5.35596781810676 1.47226037351777 0.142115251572387 2.92104234698184 17.5907352604493 0.166055727843819 0.868237371142728 KCNB2 other 1 1 1 1.47226037351777 0.166055727843819 1.33297438458714e-07 34.1060502068025 7.96011790345728 4.28461621051987 2.5453930926377e-05 -13.3142747557397 14.6385616461003 -0.909534357105819 0.363876330242941 BRICD5 other 0.00126565917816548 1 0.252808441960777 4.28461621051987 -0.909534357105819 0.00012434918741499 -2.08401404171985 13.9708307182989 -0.149168942329981 0.88153168266337 -88.4767096469314 22.9550867805313 -3.8543400202682 0.000145080891811608 IGIP other 0.910236051877725 1 1 -0.149168942329981 -3.8543400202682 0.000393796203768782 208.150914172749 152.032996887302 1.36911669462811 0.172096432236703 -1190.5178093432 398.694043991851 -2.98604362739749 0.00308452449803215 TSKU other 1 1 1 1.36911669462811 -2.98604362739749 0.000334029676555013 1669.53996515801 1013.9569425942 1.64655903522541 0.10080357197079 -5431.07262298726 1979.50331521135 -2.74365421934511 0.00647992216430884 ANXA2 other 1 1 1 1.64655903522541 -2.74365421934511 0.341304774742245 26.8893220306572 18.7670797537269 1.43279201578058 0.15306982627442 13.10688672791 34.490701340281 0.38001218353315 0.704234021009454 RGS6 other 1 1 1 1.43279201578058 0.38001218353315 0.310848462853832 5.79700567377056 11.4624702029901 0.505737905626867 0.613450252616729 -29.9234919575393 25.1036571811736 -1.19199731503585 0.234301238056408 HOXB4 other 1 1 1 0.505737905626867 -1.19199731503585 0.77870989715549 -30.8854318867819 65.6547973023662 -0.470421555709667 0.638433642625992 -77.372475125338 120.100968569454 -0.644228569069314 0.519974131901767 SLC35D3 other 1 1 1 -0.470421555709667 -0.644228569069314 0.000133715693139775 59.2409612361037 55.2283589294536 1.07265474449052 0.284380304133939 -220.729041152435 79.2958906918035 -2.78361260875843 0.00575409440669962 PAQR7 other 0.975723412840935 1 1 1.07265474449052 -2.78361260875843 0.286837587749143 29.5165716895932 33.8406287276227 0.872222910725653 0.383858894215773 98.7551912895668 62.9200364697771 1.56953487045423 0.117690194464283 PAPPA other 1 1 1 0.872222910725653 1.56953487045423 3.18685471174823e-09 69.9944612555198 10.856023427646 6.44752304764483 5.24389912405237e-10 39.3475187921688 40.8610036069093 0.962960165411 0.336432344962399 MAFA other 3.34269190715271e-05 1 6.84066640732632e-06 6.44752304764483 0.962960165411 1.59470328118661e-19 1323.64510915488 145.234106215521 9.11387237919621 1.82737273413912e-17 -553.077530097305 352.686886868844 -1.56818285762629 0.118005332666718 NGRN other 2.31550916428296e-15 1 2.74818585487182e-13 9.11387237919621 -1.56818285762629 0.0764852815355145 -8.81610465585574 9.00968499654663 -0.978514194362501 0.328699259021384 -28.6327570368264 12.9095128503089 -2.21795797942455 0.0273931683336362 GRID1 other 1 1 1 -0.978514194362501 -2.21795797942455 6.84680883133312e-08 3286.79030614111 623.454369848483 5.27190194679346 2.76807374384086e-07 -840.155162837134 1214.22815975287 -0.691925282813509 0.489578830270528 RPS17 essential 0.000662291818254853 1 0.00318688330128399 5.27190194679346 -0.691925282813509 0.117995897037355 118.08906849707 62.6464246201873 1.8850089085374 0.0604945716619258 -38.199833430721 129.936271335563 -0.293988991973375 0.768990528487066 HCAR2 other 1 1 1 1.8850089085374 -0.293988991973375 0.0583366380252154 5.08383066577268 2.12916739890881 2.38770829779665 0.0176341859659064 2.85443981226392 5.75064097418991 0.496368983053411 0.620033520927726 CCDC87 other 1 1 1 2.38770829779665 0.496368983053411 0.822975597197001 2.45770648999274 4.08513639565644 0.601621647836758 0.547940345175251 3.46506408050553 9.75931145499785 0.355052105518267 0.722832970851337 GSTA5 other 1 1 1 0.601621647836758 0.355052105518267 0.706532545061769 -120.223876013737 144.351832088799 -0.832853135800731 0.405655575257165 -16.2309529235478 410.966421278631 -0.0394945963542441 0.968524928084924 C1orf116 other 1 1 1 -0.832853135800731 -0.0394945963542441 0.00592563432142551 33.9311520147981 34.0819920235289 0.995574202099846 0.32034191484351 -234.471984653505 91.221630783245 -2.57035510810635 0.0106920205962102 TMEM198B other 1 1 1 0.995574202099846 -2.57035510810635 0.197438112862799 -103.78228916076 123.776467578787 -0.838465430391281 0.402508290096193 -530.600181842744 294.33571257277 -1.80270405247397 0.0725456030345711 CRIP2 other 1 1 1 -0.838465430391281 -1.80270405247397 1.16301075865628e-19 109.350599153718 15.3324063892178 7.13199196380658 9.15028360086729e-12 -60.9956370230774 27.4669530127682 -2.22069178895538 0.027205019609335 DDX28 other 1.69194805169316e-15 1 1.26090908019951e-07 7.13199196380658 -2.22069178895538 1.12950575742359e-07 321.427336390333 57.5687797085722 5.58336198921499 5.76223890929745e-08 -148.068094858806 154.403107461108 -0.958970951385174 0.338434498292318 ACBD3 other 0.0010783391466123 1 0.000690143354166556 5.58336198921499 -0.958970951385174 5.76975504254922e-18 538.470721532506 91.840805688342 5.86308795416914 1.33734245889789e-08 -653.401488452808 177.488306462397 -3.6813776720059 0.000280671525276299 C16orf72 essential 8.17170406676246e-14 1 0.000165121673400122 5.86308795416914 -3.6813776720059 0.0563852335931267 3.06933804247173 2.81260658219491 1.09127883789437 0.276180236494347 -35.3487343298912 18.2488456797405 -1.93703946815303 0.0538450127014862 PLCXD3 other 1 1 1 1.09127883789437 -1.93703946815303 1.25795513447686e-08 92.1310376164202 19.4610027892303 4.73413619093696 3.54940069393271e-06 -90.7716056045085 44.4137578240919 -2.0437722465193 0.0419428168970695 RRP7BP other 0.000127355377814437 1 0.0377727221848319 4.73413619093696 -2.0437722465193 0.0333917313781961 -19.1624472573839 7.8397679266422 -2.44426205427119 0.0151502144309616 4.96478802491484 23.3614194031861 0.212520820727089 0.831859914111122 VMO1 other 1 1 1 -2.44426205427119 0.212520820727089 9.90363832797206e-25 218.095356952633 27.1774432797434 8.02486660381293 3.27276341077652e-14 -258.734247372063 58.0762093093333 -4.45508152906395 1.23627534683212e-05 ALG12 other 1.51347400928069e-20 0.189867167766478 4.73110678661853e-10 8.02486660381293 -4.45508152906395 0.0650411364911414 -4.29583264701058 41.6237995145808 -0.103206163231344 0.917876533743955 -119.099748217521 59.1630707906002 -2.01307583642944 0.0451065031042679 LCK og 1 1 1 -0.103206163231344 -2.01307583642944 0.0010924144934913 -417.74149331718 483.633804745573 -0.863755778066306 0.388483090324954 -2564.6564969157 722.950523149208 -3.54748549837675 0.000457912814540527 COL18A1 other 1 1 1 -0.863755778066306 -3.54748549837675 0.126166877413492 -16.4581105050311 8.19238206239981 -2.00895299800142 0.0455264917965095 -21.223886414951 14.3244877936175 -1.48165063356804 0.139586573015231 ADGRG3 other 1 1 1 -2.00895299800142 -1.48165063356804 2.13629159875877e-11 2564.84685190494 354.970980541096 7.22551135868977 5.62954011972762e-12 -1572.17086763877 2566.37848023073 -0.612602887590228 0.54067851875152 RPL35A other 2.50052931634714e-07 1 7.78903170965514e-08 7.22551135868977 -0.612602887590228 0.325442783190368 2.33158401167936 2.30775998766112 1.0103234409755 0.3132796572793 -4.40545368076446 6.62713438117824 -0.66475997427733 0.50679320183956 SLC25A18 other 1 1 1 1.0103234409755 -0.66475997427733 1.64801815912733e-67 378.240930245798 16.4036071863566 23.0583996525101 4.22867097244455e-65 140.820886409246 44.9136608448372 3.1353686998648 0.00191113185618722 ZNF721 other 2.62941297288765e-63 1 6.74430733395181e-61 23.0583996525101 3.1353686998648 0.000726820354034788 70.76613098115 33.416478606173 2.11770162305723 0.0351212119713528 -93.6504349927506 59.4853790127735 -1.57434375550739 0.116587731430748 C11orf54 other 1 1 1 2.11770162305723 -1.57434375550739 1.30214236536153e-16 112.073237895761 13.1956529645241 8.49319379624977 1.31345212602481e-15 -129.942183698107 66.6490363030522 -1.94964835061174 0.0522417592242663 CEP63 other 1.79161768050093e-12 1 1.93576574333537e-11 8.49319379624977 -1.94964835061174 8.64772015349904e-20 915.730808297169 150.746315442077 6.07464803110913 4.22595316490334e-09 -1130.35994030016 271.042051317087 -4.17042276210408 4.10513460811816e-05 SRPRA other 1.26049168957402e-15 0.621435276976928 5.33188510815854e-05 6.07464803110913 -4.17042276210408 0.867062910491767 0.370301857733196 31.1689042799683 0.0118804900681473 0.990529640648191 -36.1996381629297 70.2813956989054 -0.515067149747761 0.606922884571664 OTOP3 other 1 1 1 0.0118804900681473 -0.515067149747761 3.96755513646286e-06 568.475629331866 149.017110945386 3.81483458997006 0.000168958778932013 -731.84450289875 390.866268670572 -1.87236546501678 0.0622368479997223 EWSR1 essential 0.0336250297815227 1 1 3.81483458997006 -1.87236546501678 0.00182526187560196 11.5335979362407 3.21401140403906 3.58853671824138 0.000395518188426788 9.92245037350956 6.246520690872 1.58847634780257 0.113362096594482 ODF3L1 other 1 1 1 3.58853671824138 1.58847634780257 2.91176090473195e-10 327.552719908037 52.7485792863958 6.2096974807531 1.98683694617355e-09 -40.7867155049933 92.0024741820396 -0.443321941802251 0.657886592366001 HMGN4 other 3.23846047824288e-06 1 2.53897893351519e-05 6.2096974807531 -0.443321941802251 0.0276895509852183 89.2230046645544 39.4173391623446 2.26354712318556 0.0243900747089659 5.20768490521253 62.9721620748815 0.0826982071700186 0.934152335270852 SPATA13 other 1 1 1 2.26354712318556 0.0826982071700186 0.000675871064274417 92.901771905793 30.5116461636454 3.04479710493252 0.00255579318029179 -69.0899351430436 63.8243295199325 -1.08250154232277 0.27998493346286 GJC1 other 1 1 1 3.04479710493252 -1.08250154232277 0.193268765697744 -4.69482393366552 15.7332327276302 -0.298401734401388 0.765629530095444 -52.2025235155392 29.8449209215763 -1.74912587815904 0.0814226297854196 SOX1 other 1 1 1 -0.298401734401388 -1.74912587815904 3.74882589554636e-27 200.390112326338 16.9223778760082 11.8417230601169 2.56316219204884e-26 -18.5374681944899 55.5829044346135 -0.333510247135375 0.739008971942674 CNOT10 other 5.80468201666398e-23 1 4.01621883872133e-22 11.8417230601169 -0.333510247135375 1.91357748361221e-24 744.751793229823 69.5194270176725 10.7128586235399 1.46277165594078e-22 43.7614937842401 165.31454232908 0.264716540769458 0.791429057135125 MTA1 other 2.92069331323732e-20 1 2.26495563205871e-18 10.7128586235399 0.264716540769458 0.061404078380386 9.33893129770975 13.3881246517154 0.697553357221929 0.486052379524172 -67.3139518496777 35.1912421506613 -1.91280408805953 0.0568231715568689 ZNF662 other 1 1 1 0.697553357221929 -1.91280408805953 0.4568538338219 118.298652625287 192.949372299277 0.613107216756311 0.54033327208468 -204.070024122658 337.3409997058 -0.604936916356537 0.545740517758122 CADM1 other 1 1 1 0.613107216756311 -0.604936916356537 0.961122428706414 -4.25695815602187 19.3480713086499 -0.220019767764589 0.826022637146551 -12.0497210337296 49.4034453781983 -0.243904467420954 0.807490724123767 ZNF320 other 1 1 1 -0.220019767764589 -0.243904467420954 0.475042724639621 -38.3048529114357 35.7229646275979 -1.07227530835565 0.284550335200652 44.8140235839518 149.19790795005 0.300366300035219 0.764128053254274 C12orf60 other 1 1 1 -1.07227530835565 0.300366300035219 7.99021582975963e-10 828.347605311613 140.938268334312 5.87737890568326 1.2390563842793e-08 -292.151542726903 313.416531870034 -0.932151029123287 0.352100601124524 PYCR1 other 8.68536460694872e-06 1 0.000153184540788449 5.87737890568326 -0.932151029123287 9.47024779329639e-08 179.440056927282 32.0414017476999 5.60025614173272 5.2165368633676e-08 -7.68661945316569 94.5313655366219 -0.0813128997929038 0.935252695679363 NAA38 other 0.000908291465855057 1 0.000626036588972746 5.60025614173272 -0.0813128997929038 0.616024181186916 -24.022651902368 46.4825761464498 -0.516809821957399 0.605708875450028 -132.279803629121 139.072969018319 -0.951153948627477 0.342370634518307 SPNS2 other 1 1 1 -0.516809821957399 -0.951153948627477 0.299901642510643 -40.4453365453097 80.8737010087293 -0.500104929548657 0.617405548915286 190.779681656968 180.321266132992 1.05799879153612 0.290994682127237 MCEMP1 other 1 1 1 -0.500104929548657 1.05799879153612 6.1306072911558e-11 268.763738254464 81.1383707861799 3.31241231060363 0.0010502217051466 -299.747267586558 125.101972941405 -2.3960235041773 0.0172499097993099 AP2A2 other 7.04161553462156e-07 1 1 3.31241231060363 -2.3960235041773 0.433765247332546 18.3781771413365 28.2805497072128 0.649852189282206 0.516334135666215 -116.050136169066 112.477901038774 -1.03175943983042 0.30309799360071 SLC8A1 other 1 1 1 0.649852189282206 -1.03175943983042 2.64106240192261e-10 29.0474924247107 6.3980432984824 4.5400587444603 8.62075526088357e-06 -23.4788279378072 11.967145232492 -1.96194058663714 0.0508402594393132 SLC25A21 other 2.94399225942313e-06 1 0.0889748150475793 4.5400587444603 -1.96194058663714 0.478517815741899 40.4239301999295 33.4971823234013 1.20678598604663 0.228570812846404 23.7725651818073 48.2062819355807 0.493142474949119 0.622312759668394 PCP4 other 1 1 1 1.20678598604663 0.493142474949119 0.00343446812742058 9.27576640229847 44.6194658381501 0.207886092494805 0.835475797176233 -243.671148973249 85.5463987429363 -2.84840919727634 0.00473444060435821 ABAT other 1 1 1 0.207886092494805 -2.84840919727634 6.26179815111397e-09 274.303279029105 51.5083995433812 5.3254086995672 2.13404159981243e-07 -152.90485098193 114.449761855599 -1.33599973038695 0.182682697437282 SLC25A10 other 6.46280187176473e-05 1 0.00247399442666255 5.3254086995672 -1.33599973038695 0.000401736772864496 5.5730716294203 102.013432126133 0.0546307629619751 0.956472734597008 -563.689687295383 171.882010324285 -3.27951532700767 0.00117533700284432 CAMK1D other 1 1 1 0.0546307629619751 -3.27951532700767 2.03169545156692e-50 236.195985715515 12.7225007053439 18.5652169479783 2.55326087419299e-50 15.1888348679117 49.4638427797857 0.307069447384685 0.75902461013633 LYSMD4 other 3.23486549798484e-46 1 4.06606794215234e-46 18.5652169479783 0.307069447384685 0.00151189001858924 8.99333846506849 2.82677306599239 3.18148583388713 0.00163699243886461 -3.12203232095863 6.45189812829155 -0.483893616867341 0.628855060357017 WBP2NL other 1 1 1 3.18148583388713 -0.483893616867341 0.0562998787937016 26.1310874012045 11.7991652503249 2.21465560035995 0.0276126700223594 36.3958407360103 19.1216437455431 1.90338452176705 0.0580459232415158 NKX2-5 other 1 1 1 2.21465560035995 1.90338452176705 9.49676458681964e-06 154.326210679804 33.32414154739 4.63106335268495 5.63466107678675e-06 -23.1988810320039 72.8907669513221 -0.318269130677368 0.750524132435683 AFMID other 0.0779874307869629 1 0.0590343441014948 4.63106335268495 -0.318269130677368 0.00142807361924036 732.66884691331 274.404808757739 2.67002918144978 0.00806228027560017 -586.688773292476 515.671910603299 -1.13771714384461 0.256285954652105 GAS6 other 1 1 1 2.67002918144978 -1.13771714384461 0.00428784689803777 106.087097324016 32.7663017318788 3.23768908044945 0.00135731439634649 30.9317783517544 75.0315774710271 0.412250140465172 0.680486883875836 NEB other 1 1 1 3.23768908044945 0.412250140465172 0.363309314345156 3.74328877295942 10.0231938140899 0.373462674910802 0.709097179593752 -23.6499170599596 22.0981722360091 -1.07022050545076 0.285475848303924 BEGAIN other 1 1 1 0.373462674910802 -1.07022050545076 0.000266089655786481 30.7911175956249 34.8999662154606 0.882267833886455 0.378456436043973 -184.410335211428 61.1019582844842 -3.01807569493654 0.0027995215077762 GPC6 other 1 1 1 0.882267833886455 -3.01807569493654 0.00109125784571243 18.6840367970666 41.8587210409659 0.44635947617179 0.655691440721694 -214.209144865173 69.8530049871836 -3.0665702199136 0.00238257937436262 ARHGEF37 other 1 1 1 0.44635947617179 -3.0665702199136 0.0223801632818532 68.3956989132541 25.979545353177 2.63267497500259 0.00897461139573406 39.6982692831098 43.2623761419653 0.917616479336229 0.359663609072907 CSMD1 other 1 1 1 2.63267497500259 0.917616479336229 0.000188843418899481 11.4129722254738 3.56092601242591 3.2050573883445 0.00151075704547274 -10.4994047890672 7.54565122638147 -1.39145111191445 0.165221458786706 PTGDR2 other 1 1 1 3.2050573883445 -1.39145111191445 3.38200259000349e-11 54.6805146661312 9.85775419325798 5.54695456938142 6.94847107647321e-08 -36.4707032637742 17.2966118405892 -2.10854608982958 0.035908428480595 CEP57L1 other 3.92684320725305e-07 1 0.000827910328761783 5.54695456938142 -2.10854608982958 0.339968728280337 11.2537727753715 10.0688860174872 1.11767803864563 0.264690740461041 -5.03706424542155 16.0444631060093 -0.313944082275646 0.753804149547301 RIPPLY3 other 1 1 1 1.11767803864563 -0.313944082275646 2.26274134935909e-07 15.7146199928734 2.90267694738269 5.4138370468829 1.3558709665488e-07 -5.30673843028241 12.5603884735927 -0.422497953900028 0.672995383656511 GPR19 other 0.00211747335473024 1 0.00159111457924502 5.4138370468829 -0.422497953900028 2.43060281468344e-05 13.0203000812243 3.30515536352309 3.93939123858476 0.000104434911437498 -5.30231065532519 7.35634441199026 -0.720780642989315 0.471677450657042 GJD3 other 0.192236376613314 1 0.977406336143545 3.93939123858476 -0.720780642989315 1.00646629932143e-05 68.7239380424819 15.1295301800168 4.54237092789919 8.35689748341651e-06 -59.1804119281562 42.6886046199167 -1.3863280951691 0.166777898981896 RABIF essential 0.0824497192404112 1 0.0863601785936262 4.54237092789919 -1.3863280951691 0.601206007460952 -50.9985478695318 51.3057861087324 -0.994011625929492 0.321103909611716 -51.4686319509323 110.378511522943 -0.46629213640224 0.641380997239714 TMEM119 other 1 1 1 -0.994011625929492 -0.46629213640224 5.82830169445074e-11 151.913556908923 28.1345001830374 5.39954703018019 1.46101348849134e-07 -54.2285789791966 51.7243534391012 -1.04841482538866 0.29538163342077 FANCF other 6.70215237028038e-07 1 0.00171055459232566 5.39954703018019 -1.04841482538866 0.130728436673478 20.3618271066176 11.2302311179299 1.81312627432114 0.0709309869210388 -11.5224640662624 37.0733548602886 -0.310801763414315 0.756192920118368 CALN1 other 1 1 1 1.81312627432114 -0.310801763414315 0.000996040770274288 113.661263175975 32.8700025671168 3.45790247335369 0.000632666827409598 -8.26721641608348 75.0233227389502 -0.110195284802966 0.912336667541104 SMDT1 other 1 1 1 3.45790247335369 -0.110195284802966 0.448819316391726 6.44371959374617 5.34904168741757 1.20464935035066 0.229397484964054 2.98609853816368 9.40813104819414 0.317395508509296 0.751189732233924 C2CD4C other 1 1 1 1.20464935035066 0.317395508509296 0.0135067222715222 -18.151801296642 40.2559843385844 -0.450909388874238 0.652416763382125 -181.991891013093 68.8076973680536 -2.64493505776854 0.00864933930362487 CHST6 other 1 1 1 -0.450909388874238 -2.64493505776854 2.84353809397163e-18 760.781743967798 92.5853573709316 8.21708492110499 8.45854901808139e-15 -262.451013721484 194.651734098751 -1.34831068901928 0.178676041801609 RUVBL2 essential 4.04976695343439e-14 1 1.23351020330681e-10 8.21708492110499 -1.34831068901928 0.0180490369973194 25.7292439997165 15.9734424653223 1.61075134903285 0.108398018764275 -69.7882370026309 38.7899498435518 -1.79913192164728 0.0731102670122588 GDPGP1 other 1 1 1 1.61075134903285 -1.79913192164728 1.91115398283975e-12 10.3052073058101 1.38544472342422 7.43819448843841 1.42149603181166e-12 0.312793003543691 4.87826198439857 0.0641197632566785 0.948923205659994 RIMBP3C other 2.33084339747136e-08 1 1.99634902707629e-08 7.43819448843841 0.0641197632566785 0.000249371331018232 158.668001146568 38.8344530094394 4.08575347019825 5.7856399060168e-05 120.807643304534 88.5786105545224 1.36384667300887 0.173743395585171 PRR36 other 1 1 0.555884282170095 4.08575347019825 1.36384667300887 1.77942072442636e-09 6.35556064266226 4.02658261218108 1.5784006575292 0.115631569003034 -27.168221915657 5.84491434810354 -4.64818135863225 5.2183529798637e-06 LINC01547 other 1.89721837638339e-05 0.0807279205984915 1 1.5784006575292 -4.64818135863225 1.04286584567652e-06 349.328617384655 280.010761945972 1.24755425454704 0.213263423662188 -1556.04725788217 406.458547546079 -3.82830492131738 0.000160056829987274 PTTG1IP other 0.00926899163637291 1 1 1.24755425454704 -3.82830492131738 7.52267685383006e-18 437.542340816079 51.0192122729377 8.57603089744618 7.5635466427296e-16 6.33094266434985 85.4237739312219 0.074112186490931 0.940975592063312 DDX41 essential 1.0631799197518e-13 1 1.11781655832901e-11 8.57603089744618 0.074112186490931 6.74462179333243e-10 38.2395950266177 6.03492551103399 6.3363822729381 9.90468715717218e-10 -11.4211972895881 16.9937536267172 -0.672082080302254 0.502110418734362 ABHD16B other 7.35905683870501e-06 1 1.28003747873049e-05 6.3363822729381 -0.672082080302254 0.835930408000632 -4.43353279854271 7.85435317441998 -0.564468225465315 0.572904141158169 0.0816331722855347 16.2055192786964 0.00503736849659911 0.995984498280957 CCDC60 other 1 1 1 -0.564468225465315 0.00503736849659911 0.191205981119023 0.339827527238975 2.45097586063258 0.138649887457997 0.889832122390463 -18.0639810426539 10.127616372984 -1.78363598870517 0.0756271383437585 PLGLB1 other 1 1 1 0.138649887457997 -1.78363598870517 8.95481893171925e-12 905.485219554192 212.669887755292 4.25770300211042 2.8468230144565e-05 -2244.84998968228 531.799867252907 -4.22123081992929 3.31531062816207e-05 DAZAP2 other 1.06392203727756e-07 0.503131540929876 0.281721605510615 4.25770300211042 -4.22123081992929 0.362104826970057 31.2811158055967 43.3223359636612 0.722055150300189 0.47088085617267 -51.7985521352369 74.0965180443903 -0.699068640502175 0.485106466383397 CCBE1 other 1 1 1 0.722055150300189 -0.699068640502175 1.33718511944861e-10 510.63354284968 238.419237921064 2.14174639304376 0.0330989332335911 -2032.89893735658 431.933372441564 -4.70651046448515 4.01079877770465e-06 SELENOF other 1.51088546646499e-06 0.0621914458470883 1 2.14174639304376 -4.70651046448515 1.81532293393565e-11 178.274933468509 25.2497197149313 7.06047177874559 1.41456424584806e-11 -18.0971247959328 95.6724364816002 -0.189157143493605 0.850112295532481 ZNF623 other 2.13245985049421e-07 1 1.93781156038726e-07 7.06047177874559 -0.189157143493605 0.0138221636279674 9.34558587293528 9.33167957033258 1.00149022504447 0.317486553577381 -26.0999028415932 14.1910673291861 -1.83917828280011 0.066986943846397 EPHA10 other 1 1 1 1.00149022504447 -1.83917828280011 8.9065543033764e-08 29.8890503500096 18.6548857289717 1.60221031553095 0.110274032426086 -118.539693575306 28.8256481348432 -4.11229933220551 5.19867182547649e-05 CCDC125 other 0.000855385475296269 0.784271631591383 1 1.60221031553095 -4.11229933220551 3.00880705585558e-09 60.4659983084284 18.5532895024476 3.25904461850021 0.00126168242033368 -103.580008116329 33.0724712718694 -3.13191013954955 0.00192845334610809 JRKL other 3.16406149993773e-05 1 1 3.25904461850021 -3.13191013954955 0.658812187116818 203.567564895656 275.730121462165 0.738285551887336 0.460977457205199 -45.3531401803316 487.618052008125 -0.0930095594155237 0.925964436679372 GBP6 other 1 1 1 0.738285551887336 -0.0930095594155237 5.29380538164703e-29 205.363924535461 19.5579053059919 10.5003026306986 8.82409030097008e-22 -221.702117880514 67.9359000776862 -3.26340149504155 0.00124597151105994 KIAA2026 other 8.26310082021285e-25 1 1.36199833795473e-17 10.5003026306986 -3.26340149504155 0.00015359314898173 31.661025543758 32.2265717550749 0.982450934725074 0.32675726372134 -147.849118026175 49.0082676026579 -3.0168199215872 0.00279809982039984 FHL3 other 1 1 1 0.982450934725074 -3.0168199215872 2.41614010728655e-05 25.6002752516899 5.89745172859627 4.34090458554432 2.00576927907003e-05 -6.48439429024384 12.9760507243584 -0.499720171259154 0.617677613122062 PMCH other 0.191213328090658 1 0.200797562527701 4.34090458554432 -0.499720171259154 0.000886042004460762 1.55685400208333 3.40245724257692 0.457567543421712 0.647629790211846 -16.1550670285023 5.73070384140142 -2.81903715068821 0.00517205302000983 C19orf71 other 1 1 1 0.457567543421712 -2.81903715068821 3.96362397439446e-05 84.7525814232784 26.6029896283781 3.18582920969419 0.00161156869574917 -70.2922290228533 51.9912840880684 -1.3520002488068 0.177498347280262 CCDC159 other 0.306625950659155 1 1 3.18582920969419 -1.3520002488068 8.33466312083981e-05 -36.2032111341987 115.659824027555 -0.313014579077809 0.754510341374024 -659.46150460885 168.650433913156 -3.91022714444026 0.000116604372365162 RIPK4 other 0.623599494701234 1 1 -0.313014579077809 -3.91022714444026 1.07310014383049e-21 313.022756743992 67.5384229195271 4.63473595048204 5.56850202308691e-06 -601.846776160193 102.708445969914 -5.85975934575516 1.34632752690523e-08 SF3A3 essential 1.60095810458071e-17 0.00021379681127255 0.058369038205997 4.63473595048204 -5.85975934575516 0.678941751583903 -15.5494200975817 20.7034784971152 -0.751053505320293 0.453279420099901 0.83405085990255 40.2134214456738 0.0207406092274269 0.983468007719766 GRIN2A other 1 1 1 -0.751053505320293 0.0207406092274269 1.59157181331965e-07 75.5031474750756 18.2678784842068 4.13310979380286 4.78980146928037e-05 -40.7517707440675 28.3601555664899 -1.43693748958907 0.151902164003989 GTF2H2C essential 0.00150308042049908 1 0.463030108035333 4.13310979380286 -1.43693748958907 3.15814300492497e-22 110.610704237246 12.0168705642944 9.2046180946562 9.45101503576286e-18 -84.6822698955563 29.3215535996227 -2.88805535517893 0.00418792337989639 ASB7 other 4.73816195028894e-18 1 1.42436247603982e-13 9.2046180946562 -2.88805535517893 2.5922041723572e-06 26.2511863905311 5.61383184385119 4.67616186603166 4.60817775296086e-06 -4.81959228684568 10.8571923169415 -0.443907793668276 0.657462182190889 SH2D7 other 0.0222929558822719 1 0.0486070589382312 4.67616186603166 -0.443907793668276 0.0228489457830442 -21.7649625703355 8.06281876521453 -2.69942351479314 0.00738269851978412 -10.3303477736372 19.3456234367314 -0.533988879056907 0.593786971898124 GPR132 other 1 1 1 -2.69942351479314 -0.533988879056907 0.000134842144423913 164.54670835403 113.845764644682 1.4453476496696 0.149524203226148 -446.02248279144 166.070152013366 -2.6857474229056 0.00768678056808845 MX2 other 0.983403759283598 1 1 1.4453476496696 -2.6857474229056 3.13118224407252e-07 269.125277330614 83.4848305359904 3.22364285347138 0.00142061457826863 -641.228799487082 172.741839441415 -3.71206420841983 0.000249504457466142 EP400 other 0.00290511088605048 1 1 3.22364285347138 -3.71206420841983 0.0716504037739127 30.3783177653102 18.4884180735383 1.64309989337538 0.101517704626316 -34.2349957317466 36.2458890426815 -0.944520789417886 0.345741819046588 MEX3B other 1 1 1 1.64309989337538 -0.944520789417886 0.000927954888339116 113.602951757542 30.1342702554645 3.76989224542251 0.000201386310824766 76.8645385465839 106.105182350038 0.724418325704485 0.469448035072095 PI4KAP2 other 1 1 1 3.76989224542251 0.724418325704485 0.168301561936757 -185.754022994733 98.2862847633682 -1.88992821777678 0.0598630023123526 -173.531211395505 171.435220452994 -1.01222613962856 0.312356746700862 FAM46C other 1 1 1 -1.88992821777678 -1.01222613962856 0.000514203653997694 98.9210484368025 25.3757515328839 3.89825098612795 0.000122198778337802 3.49604152940421 108.893252373601 0.0321052172949126 0.974411775196639 COA5 other 1 1 1 3.89825098612795 0.0321052172949126 1.46881669886374e-17 103.729694473582 33.070140929704 3.13665716436095 0.00189787577356919 -300.50463921716 50.291117797391 -5.9753024466032 7.23137280553476e-09 UTP11 other 2.06471563359276e-13 0.000114957133489586 1 3.13665716436095 -5.9753024466032 2.611832037895e-12 241.52467519129 42.6087160526374 5.66843354052063 3.67194267984777e-08 -122.370620392805 68.5968924677754 -1.78390909544905 0.0755531754902645 PSMG1 essential 3.16841344517043e-08 1 0.000443460517445216 5.66843354052063 -1.78390909544905 1.34089041968266e-15 317.017095453566 49.950329087121 6.34664678386081 9.25622791327179e-10 -471.305746298521 130.127095643406 -3.62188784717106 0.00034926924427376 PRR14L other 1.80041356650791e-11 1 1.1975707674191e-05 6.34664678386081 -3.62188784717106 0.0677778794783653 16.3652882784628 9.10822684367988 1.79675896959225 0.0734873660610796 -15.0263600569348 20.7867284961265 -0.722882393914695 0.47037554342106 SERHL2 other 1 1 1 1.79675896959225 -0.722882393914695 0.223169977402125 2.82593619813852 17.269826096847 0.163634317004179 0.870140546327401 -36.7027917254663 26.1927413817234 -1.40125812684412 0.162276831203191 PCBP3 other 1 1 1 0.163634317004179 -1.40125812684412 5.11876251959845e-21 295.346725647275 37.6881354144435 7.83659691304566 1.08126742336263e-13 -277.989793774735 88.7133229146682 -3.13357435660626 0.00191793805827788 SETD3 other 7.57935166276942e-17 1 1.55064561184434e-09 7.83659691304566 -3.13357435660626 0.150894607016541 12.5545936974647 9.58069509159969 1.31040530748886 0.191172386183518 -13.7832695893953 18.4729480400278 -0.746132645397433 0.456236420353282 TNFAIP8L3 other 1 1 1 1.31040530748886 -0.746132645397433 0.000198535634518758 153.398283311318 45.8568093080036 3.34515823551956 0.000938972953675822 -149.858623693493 121.486146077591 -1.23354496403055 0.21844527187751 ZNRF3 other 1 1 1 3.34515823551956 -1.23354496403055 0.000272728584294719 78.2264327083737 20.3425022504135 3.84546757057793 0.000151004147448478 -144.273352302405 143.005110705414 -1.0088685054033 0.313964976936155 FBXL7 other 1 1 1 3.84546757057793 -1.0088685054033 2.31595716042987e-57 259.812424205746 12.6895030560924 20.4745940843607 3.22881923601323e-56 -1.32901334901073 55.9742580565214 -0.0237432954925231 0.981075513280143 TANGO2 other 3.69070933086104e-53 1 5.14609209835789e-52 20.4745940843607 -0.0237432954925231 6.65334048206599e-10 76.2563486530116 14.4459271411391 5.27874382225346 2.7033641652854e-07 -32.8053990507117 28.8729252303262 -1.13619935593693 0.25689574169511 SMG1P5 other 7.26278647022323e-06 1 0.00311697888257407 5.27874382225346 -1.13619935593693 5.98266402186615e-12 241.230870614717 37.240939971348 6.47757201618197 4.39253548798421e-10 18.4261347312919 51.7072947043865 0.356354646605187 0.721853293756123 SFXN4 other 7.14928350613006e-08 1 5.74675417892975e-06 6.47757201618197 0.356354646605187 0.660305400526803 6.40617632970473 22.2613393842363 0.287771378852481 0.77374250695542 -98.0461429768567 115.065746615935 -0.852088009337081 0.394920404536033 GKN2 other 1 1 1 0.287771378852481 -0.852088009337081 0.432059254000565 1.65542432565985 9.27433821065773 0.178495143055867 0.858468989930213 -12.8154527918982 13.1823220006838 -0.972169606480062 0.331842786831347 FAM167B other 1 1 1 0.178495143055867 -0.972169606480062 0.000622824311529848 103.377395924406 42.5536927487658 2.4293401875776 0.0157741598872981 -78.3363961934229 71.503384878324 -1.09556206781996 0.274239569040861 MRPL54 essential 1 1 1 2.4293401875776 -1.09556206781996 2.85712955095126e-05 20.4418464311501 11.0936351296703 1.84266439198796 0.0664622169755224 -51.7317815525538 19.1139930584511 -2.70648740921673 0.00722836331437753 ZNF438 other 0.224341812340693 1 1 1.84266439198796 -2.70648740921673 1.54609991893886e-18 604.166737041674 62.8305037785908 9.61581876170696 5.04171712292956e-19 -28.2430281239645 239.966751944855 -0.117695588639108 0.906396045775776 HMCES other 2.21154132405014e-14 1 7.67500597623567e-15 9.61581876170696 -0.117695588639108 8.17687573090752e-11 139.93703905688 24.1631431958863 5.79134253861077 2.01632136839774e-08 -215.293038224283 92.2414051021236 -2.33401733186875 0.0203600384795112 DGCR6 other 9.34044514741566e-07 1 0.000246575940141359 5.79134253861077 -2.33401733186875 0.716602547465396 9.76645624976224 11.9734811041406 0.815673918455082 0.415405635290634 9.83860643165878 21.5689689586151 0.456146348512827 0.648651425666779 C11orf88 other 1 1 1 0.815673918455082 0.456146348512827 1.93141121241405e-12 30.2496073305851 6.04152081040663 5.00695243463857 9.99514699213083e-07 -44.0022481312578 13.4107215531918 -3.28112458056257 0.00116994412820987 ZNF530 other 2.35496969129645e-08 1 0.0110866170436715 5.00695243463857 -3.28112458056257 8.07785126296924e-10 243.610817002416 41.4562138929895 5.87634021841082 1.22311546828513e-08 -47.443920416345 88.7532448976371 -0.534559840274732 0.593390935481065 NDUFB1 other 8.77658539721608e-06 1 0.000151287152272188 5.87634021841082 -0.534559840274732 6.7499389741169e-07 87.7315326982847 17.7219831529906 4.95043539658707 1.30846758459024e-06 -24.6523782110001 35.542285402775 -0.693607007305033 0.488527179640114 KLHL25 other 0.00609451989973015 1 0.0143892180277388 4.95043539658707 -0.693607007305033 5.74880082700328e-13 68.6728108695209 8.68669489115125 7.9055166239895 6.83761866911561e-14 33.8653596289648 37.6058442494564 0.900534486191049 0.368638399870662 TRMT12 other 7.15035846862668e-09 1 9.8297605987206e-10 7.9055166239895 0.900534486191049 9.50977240046248e-20 58.7772307377298 5.78349247684536 10.1629302662792 1.1357134898654e-20 15.6472768605992 39.5835516002456 0.395297446237799 0.692945039054061 GUSBP1 other 1.38528854557537e-15 1 1.74434234908427e-16 10.1629302662792 0.395297446237799 0.139993623279624 4.42656551225898 4.99606264257608 0.886010810700433 0.376403064205155 -13.0667730715535 9.78816517321936 -1.33495633147921 0.183019326042817 GPR1 other 1 1 1 0.886010810700433 -1.33495633147921 0.333936301069403 1.69720786491391 2.00128636852838 0.848058474590983 0.397156580933496 -4.90754210528965 5.46916745620172 -0.897310631753427 0.370352586415699 BMP8A other 1 1 1 0.848058474590983 -0.897310631753427 2.84049124437243e-19 722.922977822186 76.7368239070327 9.42080921537766 2.21908344836612e-18 34.7871994201554 170.646265914198 0.203855614617706 0.838621619849482 ALYREF essential 4.10848653586028e-15 1 3.36302096599886e-14 9.42080921537766 0.203855614617706 0.0470223755216088 5.88242562494014 37.6643602251944 0.156180155185678 0.87600903886539 -266.063723202947 113.458096004657 -2.34503955708922 0.0197576923404674 RFLNB other 1 1 1 0.156180155185678 -2.34503955708922 6.94747004891086e-05 474.052456514076 106.492034854214 4.45152970513752 1.2436135839669e-05 464.448025143945 297.307365895465 1.56218135983636 0.119403709331736 UPP1 other 0.524464513992281 1 0.126724224206227 4.45152970513752 1.56218135983636 8.97897658889174e-07 87.3038096382646 27.6344219371956 3.15924139237213 0.00176371927463452 -115.741524122368 44.9630217976821 -2.57414914511672 0.0105883140500493 TRIM52 other 0.00802361347983365 1 1 3.15924139237213 -2.57414914511672 2.38731345084695e-07 135.40772850181 70.7542334158107 1.91377564231445 0.0567021659016337 -415.667366850497 122.723751966807 -3.38701645108539 0.000811356956844659 CMTM4 other 0.00223022822578122 1 1 1.91377564231445 -3.38701645108539 1.7283356734264e-16 56.5673176681079 98.50296114258 0.57427022509738 0.566264847865676 -1023.83335715702 145.351651842872 -7.0438370955963 1.56475980686223e-11 TMEM50A other 2.37110371037368e-12 2.49563541596458e-07 1 0.57427022509738 -7.0438370955963 0.618763413173083 0.124067687310646 12.1364722660568 0.0102227141949344 0.991851781835955 -36.1072843280475 39.5063990441139 -0.913960401395458 0.361621798612781 NPBWR1 other 1 1 1 0.0102227141949344 -0.913960401395458 0.199774554202384 20.4005412367781 24.8190014499335 0.821972684031282 0.411809741332247 -23.3600785834167 36.4993169666171 -0.64001412971049 0.522700169944057 ASCL2 other 1 1 1 0.821972684031282 -0.64001412971049 1.08980955848639e-11 130.632914744083 20.0518590472823 6.51475329225339 3.54774421771798e-10 -86.6072948473309 59.1099216764855 -1.46519048564032 0.144032439554558 TBK1 other 1.29087942202712e-07 1 4.65570473691131e-06 6.51475329225339 -1.46519048564032 1.20954045152282e-08 523.742507492506 125.218614370412 4.18262500448384 3.88696479330125e-05 -965.774512524515 314.911530187676 -3.06681216768706 0.00238071679106173 CBX6 other 0.000122574829357323 1 0.379251154882403 4.18262500448384 -3.06681216768706 0.0103593110611206 -91.0164452333847 36.7796768667848 -2.47463961043063 0.0139517037980922 -242.573377958852 101.987736016673 -2.37845634615514 0.0180811879186638 MACC1 other 1 1 1 -2.47463961043063 -2.37845634615514 1.53742436669759e-19 302.717597812622 43.3063683093083 6.99014047196277 2.15019307534867e-11 -161.921955767362 79.3567404426537 -2.04043103161947 0.0422802107794059 TBL3 essential 2.23295515019158e-15 1 2.9298530844701e-07 6.99014047196277 -2.04043103161947 0.000726200948542099 34.6934974358844 10.9081429825829 3.18051363016417 0.00164229313811021 -127.748112288325 78.5270042649067 -1.62680486138722 0.104949340278283 ACP7 other 1 1 1 3.18051363016417 -1.62680486138722 6.38759316948793e-08 916.987276825936 209.747823209053 4.37185598780679 1.75986330025482e-05 -1265.83915393161 555.674393276734 -2.27802318992447 0.0235068582252989 KREMEN1 other 0.00061908552998677 1 0.17707744527164 4.37185598780679 -2.27802318992447 1.26893859554772e-14 112.951314700642 13.569513434375 8.32390308222167 4.23511975730928e-15 36.9240217091481 31.752880854931 1.16285580126863 0.245910959417525 TRAIP essential 1.65939100139776e-10 1 6.20445044445809e-11 8.32390308222167 1.16285580126863 7.0421709550774e-13 159.0607441957 25.8775018968987 6.14668080518091 2.81869363939161e-09 -165.671192489771 67.4355647618431 -2.45673322489192 0.0146479362261946 CHEK2 ts 8.73017933300945e-09 1 3.5808683994831e-05 6.14668080518091 -2.45673322489192 0.0387477693149994 19.442682846035 7.58810706717158 2.5622573158133 0.0109465485115458 18.0306306821775 39.0411651006944 0.461836388224409 0.64457331618102 FOXL2 other 1 1 1 2.5622573158133 0.461836388224409 3.6549360320663e-12 47.1910956820208 6.40721372469318 7.36530693523582 2.66059227928608e-12 -0.675561006128178 27.2923730001541 -0.0247527397534969 0.980272254560796 AIFM3 other 4.40894933548158e-08 1 3.71338864419958e-08 7.36530693523582 -0.0247527397534969 0.00561355179407352 18.9582146176464 5.89234523851514 3.21743106526186 0.0014499691197225 10.9967729648193 9.85213324253168 1.11618191655653 0.265329349935659 KCTD16 other 1 1 1 3.21743106526186 1.11618191655653 0.241115795408186 58.0613847097448 49.174846202976 1.18071309201636 0.238751960816912 -30.1392430638236 70.899950198637 -0.42509540527721 0.67110446553151 B3GALT5 other 1 1 1 1.18071309201636 -0.42509540527721 0.000407872562222521 328.59772617909 135.130780794116 2.43170152831234 0.0158353910157593 -369.225062383383 279.400086752462 -1.3214922968528 0.187722467184044 ZNF703 other 1 1 1 2.43170152831234 -1.3214922968528 0.00446877605393746 42.6466805670293 14.7504925436278 2.89120383206815 0.00414861429903487 79.7722550081707 40.126756310905 1.98800656574605 0.0478170308950256 SLC35F3 other 1 1 1 2.89120383206815 1.98800656574605 0.0208609988812987 5.01389458230454 3.32732947458632 1.50688250760857 0.133040952043534 -15.3942043828027 9.42106088334877 -1.63402026304821 0.103451029274531 TUBA8 other 1 1 1 1.50688250760857 -1.63402026304821 3.8621184964005e-06 182.097675094907 36.5176412118939 4.98656728780163 1.10552189863314e-06 31.3757724139556 126.680548667552 0.247676322402858 0.804574502876362 EMILIN3 other 0.0327507648494763 1 0.0122171225017949 4.98656728780163 0.247676322402858 0.108416506666004 -50.0914611551924 29.8606269856672 -1.67750868658035 0.0945875261409785 -95.8049690239875 46.9887983128928 -2.03888953248035 0.0424242509329685 OLFML1 other 1 1 1 -1.67750868658035 -2.03888953248035 0.940547400387594 -2.4654140096383 8.91692462692196 -0.276487030314772 0.782383225132658 -4.88967856041796 16.1804419641777 -0.302196847975064 0.762732106535665 FAM162B other 1 1 1 -0.276487030314772 -0.302196847975064 1.1016095787818e-05 87.5281221071901 20.7722106471355 4.21371242541584 3.43579147065136e-05 -86.4370684059881 73.6302442225061 -1.17393428907801 0.241463501291801 RBM12B other 0.0898803255328067 1 0.337085501185605 4.21371242541584 -1.17393428907801 0.0537479484447356 -14.4754655631097 5.96518875467187 -2.4266567510999 0.0158960492528952 -15.7545339152509 19.5931398598204 -0.804084185994031 0.422058369574927 CCR4 other 1 1 1 -2.4266567510999 -0.804084185994031 2.55429436034133e-12 103.033528518019 13.8698981030162 7.42857141074552 1.44628345683356e-12 -37.8940903119847 38.2725980445151 -0.990110215875858 0.323006715494613 LIN9 other 3.0996362062742e-08 1 2.0298588316659e-08 7.42857141074552 -0.990110215875858 0.06608706816783 21.9697311330503 29.6981666571034 0.73976725185477 0.46008395007725 -111.726684872603 62.1006222729143 -1.79912343521449 0.073115734291496 BTBD9 other 1 1 1 0.73976725185477 -1.79912343521449 7.59322527517786e-19 216.00467660619 24.9689282825552 8.65093904559386 4.58992449697262e-16 -52.1560613897742 59.3751578307589 -0.87841554103213 0.380496400997835 NUDT14 other 1.09182986231782e-14 1 6.80869399880918e-12 8.65093904559386 -0.87841554103213 0.66022662792453 1.97559726263162 3.43495778834516 0.575144553256184 0.565672504141915 8.33684041579587 11.0136100731406 0.756958014713753 0.449735050332478 ANKRD45 other 1 1 1 0.575144553256184 0.756958014713753 0.03406495294978 14.2006760976866 8.82802614354993 1.60859017256786 0.108874608374807 -58.3056624193864 33.4332977633129 -1.74393991379954 0.0823076564166963 MAATS1 other 1 1 1 1.60859017256786 -1.74393991379954 0.0975487283859777 -74.8210687176729 49.8192911359261 -1.50184932406068 0.134296026946698 -254.600609439596 127.170050390512 -2.00204850637215 0.0462722961297252 GPR39 other 1 1 1 -1.50184932406068 -2.00204850637215 0.0498501075591164 17.4088113257163 87.8829242590221 0.198090942836704 0.843123527282326 -254.745440618465 128.197396158089 -1.98713428082673 0.0479216725276611 FAM3B other 1 1 1 0.198090942836704 -1.98713428082673 0.00335788357940444 13.5550941620146 3.97757750336866 3.40787681711661 0.000757326540159089 12.6304148371453 8.19867374433495 1.54054365754858 0.124630178895837 ZNF730 other 1 1 1 3.40787681711661 1.54054365754858 2.2591222006216e-06 329.199220756202 63.0234565924506 5.22343962954954 3.49714902693914e-07 72.2913100923047 206.899432763771 0.349403133332143 0.727057034871381 IQGAP3 other 0.0195301114243737 1 0.00400178763152646 5.22343962954954 0.349403133332143 1.11822020255034e-10 222.904077951184 52.909209992164 4.21295419047453 3.43897103864174e-05 -460.59100422086 124.896396749841 -3.68778456550187 0.000273470558174177 TOB2 other 1.26884446383387e-06 1 0.337328669180368 4.21295419047453 -3.68778456550187 0.0735501341671256 18.838671875 8.30984803129085 2.2670296501287 0.0241706838019709 28.8278076171876 25.952689455629 1.11078305261865 0.267639098016281 SCN5A other 1 1 1 2.2670296501287 1.11078305261865 0.0693237779638882 60.1404321743978 42.0986346573449 1.42856015792201 0.154273788156688 -66.2391752189992 70.2533680805761 -0.942861204078175 0.346585527033154 ARSI other 1 1 1 1.42856015792201 -0.942861204078175 4.55044925383593e-06 43.9770567418187 8.92146180348529 4.92935549246408 1.44762397071513e-06 -3.97106578127695 29.0980011926531 -0.136472115558219 0.891550526511705 TTC32 other 0.0383921403546137 1 0.01587030159095 4.92935549246408 -0.136472115558219 0.755586294512872 29.6819271005823 71.4415821273173 0.415471301400991 0.678123282927054 -82.9271687674116 191.083590401607 -0.433983727190392 0.664643026448743 LRRC55 other 1 1 1 0.415471301400991 -0.433983727190392 0.054619759824693 60.2972643278288 25.7808029397335 2.3388435367503 0.0200652082666129 96.5699533512556 76.0607955205489 1.26964164245647 0.205293511633042 DNAH2 other 1 1 1 2.3388435367503 1.26964164245647 6.28518290243188e-09 32.5544716215313 5.12933752966262 6.34672049426869 9.16356067746976e-10 22.5899816151143 21.9734459644386 1.02805821406772 0.304835784761438 HTR7P1 other 6.48442320043898e-05 1 1.18567311605781e-05 6.34672049426869 1.02805821406772 6.94795157260589e-05 199.433083438138 59.6698297555012 3.34227672938436 0.000947482419869108 -243.264816852697 124.278852494834 -1.95741119240548 0.0513216713420651 KMT5A other 0.524464513992281 1 1 3.34227672938436 -1.95741119240548 0.778072899877788 10.5578019553722 14.9331600856359 0.707003868894945 0.480171554899653 11.1961219388262 40.1172747986188 0.279084808103957 0.780392601510892 KCNH8 other 1 1 1 0.707003868894945 0.279084808103957 0.000322937368086265 205.633756391181 63.3036944676417 3.24836896362017 0.00130698647289383 -270.251719348679 201.829287305513 -1.33901141383705 0.181689008717361 SMTN other 1 1 1 3.24836896362017 -1.33901141383705 0.342559449878631 3.94910631994536 8.86984358705838 0.445228405798196 0.656511444024337 -14.5888984985639 16.2535419797332 -0.897582724845761 0.370207717127609 NPW other 1 1 1 0.445228405798196 -0.897582724845761 4.35487317041004e-12 15.1816480966451 2.4446823731447 6.21006976751596 1.99161942861495e-09 -12.2599356056962 6.20184248101748 -1.97682150799883 0.0490791514768659 PP2D1 other 5.23150913961359e-08 1 2.54489130588419e-05 6.21006976751596 -1.97682150799883 1.17653826868703e-07 212.288042338122 58.1221316869143 3.65244763357358 0.000312356721177419 -269.159305093731 109.078128479261 -2.46758272117683 0.0142280701305374 COA3 other 0.00112182923919308 1 1 3.65244763357358 -2.46758272117683 0.0108428827209987 12.4847633591624 4.89385098864079 2.55111228113422 0.0112962016533923 -6.57506541061527 10.882876755022 -0.604166118814235 0.546246208951206 NPB other 1 1 1 2.55111228113422 -0.604166118814235 0.189756671685747 15.357523305969 10.0322880740846 1.53080964108683 0.126987216750023 -0.757322087957986 16.9540916941555 -0.0446689862022543 0.964404172570543 ST6GALNAC3 other 1 1 1 1.53080964108683 -0.0446689862022543 9.62111856371326e-11 211.011890823452 167.610020281027 1.25894555987556 0.209145475137439 -1220.15514099883 238.236864744331 -5.12160509796946 5.7960357298652e-07 PTP4A2 other 1.09555677085003e-06 0.00910093530303434 1 1.25894555987556 -5.12160509796946 1.83371892014463e-11 16224.4055046643 2295.18600410847 7.06888482049908 1.35378048639631e-11 2566.71041794355 5097.2390205757 0.503549158197736 0.614991865601956 ACTG1 other 2.15370287170987e-07 1 1.85576229075206e-07 7.06888482049908 0.503549158197736 0.847196730723067 -79.0325396435055 169.482533728726 -0.466316722465367 0.641363423801917 -131.597977556181 247.132512040144 -0.532499655629303 0.594816310360614 TMPRSS2 other 1 1 1 -0.466316722465367 -0.532499655629303 4.31444381633736e-13 452.523204085739 89.9546338709401 5.03057135149907 8.87678053348477e-07 -266.030124112673 139.894212316216 -1.90165211060583 0.0582693101663875 DENND5A other 5.3852887715523e-09 1 0.00987808137766186 5.03057135149907 -1.90165211060583 9.21649449173465e-10 339.034034505785 55.7695258387364 6.07919879911008 4.05423520494993e-09 -113.256775683475 115.675007584927 -0.979094603476232 0.328400076289634 DIABLO other 9.97593363785358e-06 1 5.11928279329028e-05 6.07919879911008 -0.979094603476232 4.86963833835355e-19 93.9386404662048 10.6127668621846 8.85147499102486 1.16604487205668e-16 -41.7676459560866 25.5501340556585 -1.63473294758845 0.103270362415779 VPS33B other 7.02201848390582e-15 1 1.74020536705739e-12 8.85147499102486 -1.63473294758845 3.81681283362987e-25 209.761403561948 18.4444617435693 11.3725955508071 1.22289882110722e-24 -14.597203383623 79.5854891592779 -0.183415388129474 0.85461342554498 TBX1 other 5.85041071138787e-21 1 1.90857819010204e-20 11.3725955508071 -0.183415388129474 0.913729367742774 4.11281757043616 16.8327270650458 0.244334596203171 0.807160761623736 -6.64965912517001 33.6753471172665 -0.197463714390653 0.843616049392221 ADAP2 other 1 1 1 0.244334596203171 -0.197463714390653 2.44705860934506e-09 320.011593342043 60.1551183727423 5.31977331270696 2.17772837148634e-07 -274.893614830952 157.792797284979 -1.74211763503049 0.0826223742059391 UQCR10 other 2.58800918524334e-05 1 0.00252355163687837 5.31977331270696 -1.74211763503049 0.511269835645464 4.52496292402699 16.5022173788711 0.274203327961284 0.784135736112647 -32.6453049616102 34.5331200087774 -0.94533320340915 0.345324714322692 TREML3P other 1 1 1 0.274203327961284 -0.94533320340915 3.08501500142864e-09 1274.36077166118 238.143410841345 5.3512325499956 1.89677639151916e-07 -253.743275547903 470.143308504202 -0.539714744330207 0.589848702327563 EIF3C other 3.24111676050093e-05 1 0.00220519223278018 5.3512325499956 -0.539714744330207 0.983740252815833 -7.67783779373938 42.5054254785596 -0.180631947740699 0.856796655412149 -6.51660655628121 183.522929055611 -0.0355084053519359 0.971701485671377 CLDN5 other 1 1 1 -0.180631947740699 -0.0355084053519359 4.69451027667354e-13 685.531179574615 108.080591296347 6.34277784153637 9.41528606208401e-10 -658.95220250147 283.506030645478 -2.32429695058404 0.0208490104679398 NIPSNAP1 other 5.85170705987357e-09 1 1.2175847935487e-05 6.34277784153637 -2.32429695058404 0.697630486256604 40.5503018318959 51.9196556427445 0.781020238480002 0.435472313691435 59.8764237600091 149.625928090533 0.40017411770893 0.689343535081727 CNTN2 other 1 1 1 0.781020238480002 0.40017411770893 0.848383222933937 0.366385091809659 8.99980848419345 0.0407103209421788 0.967556699300249 -18.5752578533316 32.6725402982801 -0.568528118222549 0.57014549610506 SPRR4 other 1 1 1 0.0407103209421788 -0.568528118222549 2.50494180165794e-13 128.707990312706 20.3938392121541 6.31112116623928 1.16449567414735e-09 -130.549162318736 52.6845646388058 -2.4779394726663 0.0138402695387696 LRTOMT other 3.15271975156668e-09 1 1.50150072224559e-05 6.31112116623928 -2.4779394726663 0.52467941439046 -12.7708776752985 12.1367323011278 -1.05225009157628 0.293622160436639 14.1720098734776 51.3067997745339 0.276220889545948 0.782588945931268 KCNQ3 other 1 1 1 -1.05225009157628 0.276220889545948 0.0669747871190018 57.1595866026599 26.9485956371972 2.12105993841707 0.0348180907403461 90.3840728686308 42.9820970725955 2.10283069055413 0.0363960460971221 ADRA2C other 1 1 1 2.12105993841707 2.10283069055413 1.26839451520824e-19 247.620524296676 32.7473739584201 7.56153835758202 6.13912798716671e-13 -199.08410059676 75.4192893561645 -2.63969738108502 0.00877706474201668 NR2C2AP essential 1.84462614346734e-15 1 8.6874800146396e-09 7.56153835758202 -2.63969738108502 0.0746933333416572 97.2923452768724 45.2608641241677 2.14959098018903 0.0324999033233197 37.2817007910652 71.0974916941713 0.524374347149037 0.60045986172313 C1QTNF12 other 1 1 1 2.14959098018903 0.524374347149037 3.87052078593332e-07 136.100402226018 47.6563952818505 2.85586858638993 0.00463045140581787 -325.683372821276 101.838232494076 -3.1980462037204 0.00155102618553699 CRELD2 other 0.00356552374800178 1 1 2.85586858638993 -3.1980462037204 8.92940186341473e-18 123.781385903524 16.7915052684572 7.37166703785913 2.74303543608523e-12 -85.952263404737 35.0208844417979 -2.45431446905869 0.0148296360581034 SCFD2 other 1.26011719096509e-13 1 3.82763164751334e-08 7.37166703785913 -2.45431446905869 3.60949047891814e-16 124.642734527608 38.5871954980657 3.23015790390508 0.00138923777131292 -341.776388223709 60.9808913642585 -5.60464730143363 5.11494609602065e-08 UBE2F other 4.91576508323861e-12 0.000810105162687751 1 3.23015790390508 -5.60464730143363 0.00475159073107486 17.9337554980973 9.51823945678328 1.88414628351429 0.0606195110998086 -29.1564738660238 23.2534125506998 -1.25385785000173 0.210978208702935 KCNJ12 other 1 1 1 1.88414628351429 -1.25385785000173 8.80663238105116e-23 291.737573170636 26.481500750331 11.016655586145 1.5327071465036e-23 -54.9193505774215 207.288876580339 -0.264941136656391 0.791257708541749 PPP1R2 essential 1.3270714335006e-18 1 2.38489231995961e-19 11.016655586145 -0.264941136656391 5.66568390746086e-14 134.109234112992 20.9360752253353 6.40565304956026 6.59072586036225e-10 -33.0104870400774 38.501192008771 -0.857388701953884 0.391987686302021 PGP other 7.27983725269646e-10 1 8.56860269105696e-06 6.40565304956026 -0.857388701953884 2.02181470581926e-05 64.8451574725492 22.4795346491629 2.8846307757071 0.00423472401577588 -125.681158467384 51.9982663901256 -2.41702593552715 0.0163109864105622 C22orf46 other 0.161259940936144 1 1 2.8846307757071 -2.41702593552715 2.53203399235094e-05 49.9749339235183 17.2491075771771 2.89724750685896 0.00407075465901855 -100.400624901745 35.9260166324486 -2.79464951344099 0.005565293297571 SNRNP35 essential 0.199954724375953 1 1 2.89724750685896 -2.79464951344099 3.76680113664476e-14 224.19887969386 31.6328091389332 7.08754251666886 1.1999401298098e-11 -267.667573774334 114.722680900385 -2.33317049142839 0.0203765382422482 CMSS1 other 4.86595370831771e-10 1 1.64751779822886e-07 7.08754251666886 -2.33317049142839 0.35128074294965 22.4180827530522 41.6162029883759 0.538686404411137 0.590565941281298 -67.081837725898 70.9236264839058 -0.94583203160262 0.345115818074263 PCDH9 other 1 1 1 0.538686404411137 -0.94583203160262 5.98949029816462e-05 34.1608943202333 12.4352785942901 2.74709521473197 0.00641417154957629 -46.2572628801557 24.3303729925344 -1.90121470371003 0.0583306810191396 ACOT1 other 0.455380947369456 1 1 2.74709521473197 -1.90121470371003 1.76166405763193e-05 220.481218023899 58.6542747481138 3.75899657732941 0.000208812002615446 -75.7061972022503 106.13110910938 -0.713327108682402 0.476254930499327 OAF other 0.141355923984386 1 1 3.75899657732941 -0.713327108682402 0.152379196084561 -143.518570977099 96.9970728035144 -1.47961754750911 0.140132579615929 -389.93282934712 236.6760009603 -1.64753852424829 0.100602091382527 ALDH1A3 other 1 1 1 -1.47961754750911 -1.64753852424829 0.00339826143610826 7.43561305283072 2.28015251274524 3.261015660693 0.00125960943501765 -6.66506311648113 7.76322768938284 -0.85854278441381 0.39138973146514 HIST2H2AC other 1 1 1 3.261015660693 -0.85854278441381 0.11721426230051 -9.92145795465414 9.4338358573684 -1.05168863489446 0.293875851477275 -48.3746917528521 23.5901410847921 -2.05063172699878 0.0412610163532748 POU6F1 other 1 1 1 -1.05168863489446 -2.05063172699878 6.73942282280304e-18 227.928605437003 29.1852307066173 7.80972429953498 1.2867148293939e-13 -216.807599373111 71.4276457748644 -3.0353457267299 0.00263806230197633 TM2D3 other 9.53223964057262e-14 1 1.84321899310676e-09 7.80972429953498 -3.0353457267299 2.48432477792997e-10 111.122145171153 36.0309359597572 3.08407600888483 0.00225122299110672 -134.984849923888 52.9878107647471 -2.54746984213385 0.0113994630404157 TSSC4 other 2.77300331712543e-06 1 1 3.08407600888483 -2.54746984213385 3.53283406165843e-05 416.036799667321 1399.30979662219 0.297315719986809 0.766453255856357 -8436.05729189178 2289.43200292992 -3.68478176294192 0.00027637043171452 TACSTD2 other 0.274713176634559 1 1 0.297315719986809 -3.68478176294192 0.083147128838505 37.1253544387675 19.2917125495596 1.92441984315255 0.055360664736324 1.04513719541247 34.9838500412563 0.0298748477991971 0.976189100636759 PRKD1 other 1 1 1 1.92441984315255 0.0298748477991971 0.000214160884120292 49.4406820328776 15.1126295783146 3.27148109974328 0.00120845757317299 0.462086818301372 23.2751201698703 0.0198532516665389 0.98417504675876 CCSER1 other 1 1 1 3.27148109974328 0.0198532516665389 1.14590260501844e-12 95.9767057784264 12.6648809893505 7.57817668078606 5.57262424707264e-13 -21.5815565597689 47.3100191540081 -0.456173067474661 0.648630885537165 ZDHHC23 other 1.40877266260967e-08 1 7.89585129567723e-09 7.57817668078606 -0.456173067474661 0.20189699276557 -8.91670603610806 10.5402579893384 -0.84596658308814 0.398314987447075 -33.4224380528363 18.6713481622641 -1.79003882110586 0.0745598841838917 MROH7 other 1 1 1 -0.84596658308814 -1.79003882110586 0.508730522541464 33.1700062517882 117.190055790909 0.283044546979058 0.77735798013892 -444.025611138778 399.33119461813 -1.11192317836173 0.267153002350758 S100A7A other 1 1 1 0.283044546979058 -1.11192317836173 0.717940436601376 -33.6713393217915 190.347204885852 -0.176894319735263 0.859723531694289 -241.449724924626 307.788648920154 -0.784465982653124 0.433451906458303 SLIT3 other 1 1 1 -0.176894319735263 -0.784465982653124 6.67829855522764e-05 49.9700431771539 47.9664301671945 1.0417711512609 0.298439472046 -266.734570935934 79.7517612442718 -3.34456025515164 0.000939583644958201 EFNA5 other 0.505079719731867 1 1 1.0417711512609 -3.34456025515164 0.730082330211756 -6.04180022805248 12.9882533521937 -0.465174189648219 0.64219608358979 -14.7380603589431 18.6796316365615 -0.788990952589044 0.430836149737454 KRTAP19-1 other 1 1 1 -0.465174189648219 -0.788990952589044 0.00453479475009834 383.398187918191 276.019791355472 1.38902426538114 0.165965737892944 -553.717209090734 441.750417142283 -1.25346165527759 0.211118056104133 PKP3 other 1 1 1 1.38902426538114 -1.25346165527759 0.679859939738952 185.537210315968 219.483802970254 0.845334406480611 0.398664416383832 234.094665560597 326.043777247481 0.71798538078802 0.473380263307541 CSF1 other 1 1 1 0.845334406480611 0.71798538078802 0.786487923013835 -2.32652854848045 4.68740423728234 -0.496336230183834 0.620058062389639 -10.6956084089055 19.2910090026966 -0.55443488764172 0.579736828452489 COLEC10 other 1 1 1 -0.496336230183834 -0.55443488764172 9.70987822752689e-15 14.2346280850049 1.66345173652834 8.55728349216363 1.03283889433271e-15 -0.450620665836794 15.5614618081438 -0.028957476578516 0.976920805509046 ACTRT3 other 1.2740331222338e-10 1 1.52426364025621e-11 8.55728349216363 -0.028957476578516 5.80460941374781e-05 87.0318948805129 30.2292651622998 2.87906088398914 0.00430435924061689 -171.21196348659 73.7487959596299 -2.32155605062775 0.0209931495851728 PLA2G6 other 0.441889733879657 1 1 2.87906088398914 -2.32155605062775 0.12428605734738 64.2662110607079 45.3177760007096 1.41812367534765 0.157312062397423 -43.2226927728513 80.7819467642519 -0.535053864188112 0.593054626501148 MAML2 other 1 1 1 1.41812367534765 -0.535053864188112 3.81264387090352e-10 173.783379501386 27.570023610771 6.30334532733198 1.17607812677417e-09 -58.6873763355755 78.2135357791222 -0.750348079152319 0.453696059828133 SS18L1 other 4.21754664999348e-06 1 1.51631752884993e-05 6.30334532733198 -0.750348079152319 0.897840428774581 -3.29650042718576 8.75217813989701 -0.376649146588845 0.706730185044755 2.68118835492586 24.0152152466648 0.111645401774952 0.911187523575586 KCND2 other 1 1 1 -0.376649146588845 0.111645401774952 1.29625212394217e-09 301.640058578827 46.4983507218811 6.48711306736482 4.18054583063733e-10 49.4360239808632 175.683381854429 0.281392716027209 0.778625538839683 TOP1MT other 1.39230440632628e-05 1 5.47609698355183e-06 6.48711306736482 0.281392716027209 1.70432789733928e-12 890.170254376976 115.18858474274 7.72793811439793 2.17998047277456e-13 160.257802824431 593.654260656357 0.269951406812521 0.787404615506351 COPB2 essential 2.08354085449727e-08 1 3.11388410731118e-09 7.72793811439793 0.269951406812521 2.28985872601473e-39 254.438165138213 16.8212162373748 15.1260266527507 5.46098700272308e-37 -95.5209630438664 71.6521919812602 -1.33311990048886 0.183725711314236 THAP7 other 3.63125796771416e-35 1 8.6649480772207e-33 15.1260266527507 -1.33311990048886 0.000269318792137645 197.021529533987 63.9673576025726 3.08003233083468 0.0022825587632647 -230.041280029655 132.673434526187 -1.73389104496462 0.0840746717378352 KNTC1 other 1 1 1 3.08003233083468 -1.73389104496462 0.606801241022192 -2.02260807345461 2.43455997934024 -0.830789995160738 0.406829045337294 -3.93205210417387 4.55861016562614 -0.862555024736095 0.389150487171007 CCR10 other 1 1 1 -0.830789995160738 -0.862555024736095 0.363831324789867 19.2401721904123 15.7736042302785 1.21977018755672 0.223608584001942 2.68865354341665 23.2192689955879 0.115794065003836 0.907901195637668 NCMAP other 1 1 1 1.21977018755672 0.115794065003836 0.00151382819799025 69.2112768923553 25.0131202288959 2.76699892932192 0.00604847405381993 -65.7568478957085 47.1511772623377 -1.39459609947496 0.164284016496439 WDR27 other 1 1 1 2.76699892932192 -1.39459609947496 1.72940286821905e-52 265.645164176181 13.8452021732406 19.1868028254299 6.54171865143994e-52 35.2961654382685 61.3282250611939 0.575528892333826 0.565425745332868 TXNRD2 other 2.7545928884993e-48 1 1.04209578117438e-47 19.1868028254299 0.575528892333826 0.482528876978068 24.0103981665751 21.7788971262674 1.10246161811455 0.271253771628529 35.3081341202918 39.8040892701354 0.887047908084738 0.375851413680906 POU3F2 other 1 1 1 1.10246161811455 0.887047908084738 0.487193754088415 32.600108357224 40.4057367863448 0.806818807180897 0.420478386115643 -104.065990933735 154.261207098628 -0.674608949917004 0.500499334787722 PTP4A3 other 1 1 1 0.806818807180897 -0.674608949917004 0.0281643863949079 23.0759833541622 11.6603276654155 1.97901671516535 0.0488610641758501 -17.7160750866433 21.8134914783106 -0.81216136831 0.417436337628614 TMEM255B other 1 1 1 1.97901671516535 -0.81216136831 0.0728754895997222 14.0213851738789 69.4982659488219 0.201751583042433 0.840285467591559 -562.220965107964 266.120779727052 -2.11265338123768 0.0356856052242007 PROS1 other 1 1 1 0.201751583042433 -2.11265338123768 0.0144616452375033 12.1594411855714 7.44756847543663 1.63267262673386 0.103694926800722 -20.7618445691563 14.1764494927376 -1.46453063440125 0.144203840926387 GAST other 1 1 1 1.63267262673386 -1.46453063440125 2.77953112391273e-15 133.663710154939 16.7820573008202 7.96467964320476 4.64562994847897e-14 -45.0517815435663 40.3791323335904 -1.11571940603808 0.265534272228758 HDDC3 other 3.70177955082698e-11 1 6.69899838570668e-10 7.96467964320476 -1.11571940603808 1.24661355103405e-16 83.1392755006059 12.918587691815 6.43563193469528 5.58356726766044e-10 -35.7074397586416 21.883985658472 -1.63166985739721 0.103914826359021 ZFP1 other 1.71583889164326e-12 1 7.27706321994185e-06 6.43563193469528 -1.63166985739721 0.715371274745092 -15.9001246768801 19.5366950122928 -0.813859491939427 0.416437342697616 -6.72593212860924 36.3756417904735 -0.184902088253209 0.853443624842937 C6orf58 other 1 1 1 -0.813859491939427 -0.184902088253209 0.00173226472367115 -4.45903597416275 45.0797753383961 -0.0989143344369071 0.921278877931756 -182.775597604866 66.98333665921 -2.7286726329381 0.00677181380619412 DUSP8 other 1 1 1 -0.0989143344369071 -2.7286726329381 0.800020578622817 141.930494344967 298.534505138304 0.475424086335395 0.634864898389935 379.579476742115 652.992336202241 0.581292391499911 0.561523024871244 SOCS3 other 1 1 1 0.475424086335395 0.581292391499911 0.159707519217386 166.901691925154 173.491934448535 0.962014127375263 0.337006733628382 -281.917114892306 284.535184410388 -0.990798784608986 0.322777564322369 SLITRK6 other 1 1 1 0.962014127375263 -0.990798784608986 0.0682600221761134 18.7212004218906 16.0714062010675 1.16487631434809 0.245089661101666 -133.605321663462 76.0672718842246 -1.75641006117337 0.0801437409790568 LPAR5 other 1 1 1 1.16487631434809 -1.75641006117337 1.10653300896909e-20 1514.80546685824 158.489828135907 9.55774565897868 7.82717933650197e-19 -538.456903580151 467.204627039448 -1.15250764315459 0.250131901512295 XPOT other 1.63158292172492e-16 1 1.18988780273503e-14 9.55774565897868 -1.15250764315459 0.189963027271172 -222.982169371808 154.338998562514 -1.44475583908554 0.14968171367513 -425.496516257994 253.84248711749 -1.67622260989372 0.0948478072094043 TMEM173 other 1 1 1 -1.44475583908554 -1.67622260989372 0.52111275279057 -19.3980764705155 30.4127492043013 -0.637827127702483 0.524122791941116 -129.587757781439 119.867466134277 -1.08109199235323 0.280613773244022 PDE4B other 1 1 1 -0.637827127702483 -1.08109199235323 4.40438372310926e-06 282.795419554208 69.3115778520893 4.08006033505242 5.93817129511187e-05 -85.0931101318366 134.907532658841 -0.630751363209813 0.528738621229385 SNN other 0.0371950205416577 1 0.570005062617788 4.08006033505242 -0.630751363209813 0.0488443148077902 362.246435621847 146.597458320138 2.4710280776545 0.0141091898735966 311.163900052421 380.694070995404 0.817359459365412 0.414465681662233 NELL2 other 1 1 1 2.4710280776545 0.817359459365412 1.40758443551477e-07 13.4701876948245 2.94546521744572 4.57319530206701 7.29199347332406e-06 -17.5510191674224 8.8483194687622 -1.98354266359662 0.0483085243941858 KRBA2 other 0.00133523459552931 1 0.0757565201943636 4.57319530206701 -1.98354266359662 0.000172523807104177 49.1719372186263 12.2088989088651 4.02754888755132 7.33056035963767e-05 16.8957826182513 28.1376207349161 0.600469484517759 0.54869707286228 ZNF93 other 1 1 0.697649429426717 4.02754888755132 0.600469484517759 1.09483037975438e-06 1558.18379198469 290.001975371885 5.37301095962036 1.6648835798947e-07 870.956930008427 643.182149664847 1.35413728515673 0.176816517383144 SEPT9 other 0.00972099894183916 1 0.00194325211445309 5.37301095962036 1.35413728515673 4.6366798413382e-13 114.134227432862 21.5524151695995 5.29565835358688 2.4486991284347e-07 -49.5374358194116 36.6314821652921 -1.35231863116769 0.177396641505471 CDCA2 other 5.7814760941646e-09 1 0.00282922697299346 5.29565835358688 -1.35231863116769 0.0453041448973976 -7.28695670534874 6.32674727292188 -1.15176984175368 0.250427019788912 -29.7083263467192 11.9389884544807 -2.4883453451678 0.0134326773505988 OR7E14P other 1 1 1 -1.15176984175368 -2.4883453451678 5.66412996061066e-09 130.966255072734 42.5760711469174 3.07605308673992 0.00231137661499049 -171.948891717256 62.9919828041068 -2.72969486056637 0.00675295649050082 ZBTB40 other 5.85487337993002e-05 1 1 3.07605308673992 -2.72969486056637 0.00652296111546078 225.04372301637 82.2130054264462 2.73732509654705 0.00662495176242062 -433.794403734158 279.910346604643 -1.54976194698107 0.122424426721877 HIST2H2BE other 1 1 1 2.73732509654705 -1.54976194698107 0.494017203845059 5.62397283091511 47.6602512166551 0.118001325787175 0.906154020467343 -80.2279698450299 85.9493662179609 -0.933432942851236 0.351427390181114 CLDN6 other 1 1 1 0.118001325787175 -0.933432942851236 1.02396899958934e-17 131.826690369779 18.5022325079262 7.12490724096708 9.41646245344694e-12 -176.483096763712 49.3042321280046 -3.57947156149849 0.000407831761225483 EIF4ENIF1 other 1.4434890987211e-13 1 1.29674104446418e-07 7.12490724096708 -3.57947156149849 0.000563150063512264 6.71568019572294 16.3020023745388 0.411954313429115 0.680698562326421 -93.9776689643091 29.2864996420647 -3.20890752097008 0.00149261689801972 SERINC4 other 1 1 1 0.411954313429115 -3.20890752097008 3.19815940997453e-07 38.5667060115906 13.3189632029428 2.89562373766973 0.00410072815234784 -36.1918191197237 19.2220599024869 -1.88282729859984 0.0608232831332531 RNLS other 0.00296501358898739 1 1 2.89562373766973 -1.88282729859984 0.0295628346645235 -94.8693057389796 36.493844934127 -2.59959743650533 0.00985864830608325 -131.649225162574 72.0462385952818 -1.82728797130008 0.0687853289086182 APOBR other 1 1 1 -2.59959743650533 -1.82728797130008 0.089768939288022 98.3914255646957 85.829554920565 1.14635833374362 0.252692799039329 -358.250949202972 254.778236116967 -1.40612854011008 0.160870832057818 FAM110C other 1 1 1 1.14635833374362 -1.40612854011008 0.00221922833526408 173.697251690551 100.613885464498 1.72637455445294 0.0854155214606415 -498.83045784478 213.797265815588 -2.33319381303524 0.020367116052167 ATL3 other 1 1 1 1.72637455445294 -2.33319381303524 9.8153012372309e-07 155.762153219648 34.1104364745491 4.56640750803255 7.52559447056879e-06 -112.193656146603 78.6106572635616 -1.42720669247741 0.154667289151096 NDUFA12 other 0.00874248881200156 1 0.0780404146597983 4.56640750803255 -1.42720669247741 1.42361145926808e-05 24.0941703402283 5.49724416539452 4.38295437046485 1.6781949099089e-05 -5.66307787950728 10.3626229644645 -0.546490777376258 0.585179940511904 TCTE3 other 0.115170167054788 1 0.169145264969718 4.38295437046485 -0.546490777376258 5.02411461615228e-16 397.993668560277 83.8811772719121 4.74473155366104 3.37080196722599e-06 -491.673978043779 121.760396791374 -4.03804513618841 7.00842891885166e-05 UBE2G2 other 6.81822594558026e-12 1 0.035946232178498 4.74473155366104 -4.03804513618841 0.208484781782534 49.476814331596 27.930307320755 1.7714382360136 0.0776075447481171 37.6396044224962 89.2290649032155 0.421831210080739 0.673481421075955 OSBP2 other 1 1 1 1.7714382360136 0.421831210080739 0.504381929393721 5.81454567669547 5.72914227687606 1.01490683870151 0.311058832904107 0.171193425951817 8.2404441159669 0.0207747814975297 0.98344065905024 B3GALT5-AS1 other 1 1 1 1.01490683870151 0.0207747814975297 0.000667196136168882 220.446002226712 134.040856587689 1.64461797573262 0.10121668088692 -546.654962681951 222.92604037697 -2.45218082982837 0.0148351229278349 ZBTB7C other 1 1 1 1.64461797573262 -2.45218082982837 0.45684452745293 9.12779940089253 9.32022528203063 0.979353945284016 0.328278590244558 17.6570887897993 15.2257860484378 1.15968323301186 0.247198513639034 PRR16 other 1 1 1 0.979353945284016 1.15968323301186 9.52834449391068e-10 1158.61827544772 210.777833824322 5.4968696395912 8.87325694159313e-08 -315.748721066026 353.100135804686 -0.894218633891093 0.371992586777327 TMED9 other 1.03029989012656e-05 1 0.00105192461042587 5.4968696395912 -0.894218633891093 0.770525675708612 1.50188621363776 5.24762072377769 0.286203270528396 0.774939501292297 6.25594406909898 8.67878989720522 0.720831376631613 0.471630064203594 DRD1 other 1 1 1 0.286203270528396 0.720831376631613 6.88631901727484e-29 100.966150656209 9.73091559305179 10.3758119871374 2.00842091034606e-21 -28.673009699967 18.6565385716768 -1.53688797039214 0.125500501313564 TMEM186 other 1.07385258755384e-24 1 3.09457493866121e-17 10.3758119871374 -1.53688797039214 2.21063722830792e-07 101.037051953282 37.1290332120109 2.72124112083256 0.00692175943056962 -152.768607399884 62.1539176573091 -2.45790793497825 0.0145965542790968 SDR42E1 other 0.0020704828280332 1 1 2.72124112083256 -2.45790793497825 3.47625292626113e-07 161.160664607688 42.3289824995682 3.80733613451096 0.000174431992188012 -207.401115877495 106.858829217567 -1.94088890357597 0.0533280724335399 RBM33 other 0.00321588158208417 1 1 3.80733613451096 -1.94088890357597 5.0227420292136e-29 652.800554627366 55.8863438418095 11.6808599337822 8.37262422517146e-26 -48.3272413447959 132.895591218059 -0.363648191048709 0.716404260831932 BTBD6 other 7.84100258180536e-25 1 1.3109017749351e-21 11.6808599337822 -0.363648191048709 4.25811756536621e-12 955.681711083852 128.673746340868 7.42716939749439 1.4468407469076e-12 -144.02833720044 491.439971240778 -0.2930741201958 0.769689787239219 H1FX other 5.11783150181364e-08 1 2.03049630421013e-08 7.42716939749439 -0.2930741201958 0.342674961254292 -6.77851323828925 11.9464170598242 -0.567409726643933 0.57090906217083 -40.889733145334 27.894543008955 -1.46586854397318 0.143852028127618 RBM43 other 1 1 1 -0.567409726643933 -1.46586854397318 3.94276218891689e-12 710.458104664545 171.126308917765 4.15165914088615 4.41611942963738e-05 -818.527130008372 248.403848788701 -3.29514672981027 0.001113757580434 SUMO3 other 4.74747995167483e-08 1 0.429070163783568 4.15165914088615 -3.29514672981027 8.22019690306109e-12 33.7535904954136 5.63784871129058 5.98696279802921 6.84254205031181e-09 -36.5785833293523 16.1276174726167 -2.26807111412827 0.0241209158912563 IMMP2L other 9.78039027526208e-08 1 8.5518090544797e-05 5.98696279802921 -2.26807111412827 6.62348751277361e-17 1270.22147795533 144.776370420464 8.77367953255299 1.96961344320887e-16 295.977343898469 347.370966190446 0.852049747117321 0.394938817819415 JAG2 other 9.18545248271444e-13 1 2.93413314634825e-12 8.77367953255299 0.852049747117321 0.958115584201737 -11.4334706263832 53.0520801498198 -0.215514087178013 0.829528044331256 -29.4116474670923 111.442604008901 -0.263917446372154 0.792043373466262 FMNL1 other 1 1 1 -0.215514087178013 -0.263917446372154 3.39777604280196e-05 1.66037776280739 3.99416893983254 0.415700434262806 0.677965641645319 -19.0690060656872 5.72272352222049 -3.33215574571183 0.000984485002755158 NUTM2A other 0.264618798213417 1 1 0.415700434262806 -3.33215574571183 6.18818752056408e-07 119.019716857971 22.1356274785034 5.37683953046077 1.63321593096022e-07 -39.5643295298485 77.3791592353516 -0.511304722367326 0.609552495481636 PTRHD1 other 0.00560649789363106 1 0.00190759620736153 5.37683953046077 -0.511304722367326 0.581259888013669 -1.64953123668553 8.68031031564401 -0.190031367163531 0.849427872011234 -16.6701166419218 16.3182435388285 -1.02156317266966 0.307905530021842 LCN12 other 1 1 1 -0.190031367163531 -1.02156317266966 0.884412912960297 -0.0326153220890001 15.9846485632346 -0.00204041533725157 0.9983735203738 15.7397632595001 35.5340902481196 0.442948254749058 0.658164527084373 WT1 ts 1 1 1 -0.00204041533725157 0.442948254749058 3.43024645163193e-11 60.5034376707129 21.762855495374 2.78012403673652 0.00581451207829064 -173.783673635893 39.9247604276207 -4.35277937236327 1.90684943746332e-05 ZFP90 other 3.9821731056995e-07 0.291404731033144 1 2.78012403673652 -4.35277937236327 0.779339694218861 4.32290738603999 6.84102375731323 0.631909424582643 0.527974869957082 -1.60299730770541 16.7927518616115 -0.0954576903723496 0.924021325572496 FAM227A other 1 1 1 0.631909424582643 -0.0954576903723496 0.288134216489482 205.634884865701 171.129996339104 1.2016296924253 0.230548398690626 17.8870902446863 263.991363310068 0.0677563463456085 0.946029191876274 MUC6 other 1 1 1 1.2016296924253 0.0677563463456085 6.31711712186463e-10 142.577888958908 24.9281958219225 5.71954304184026 2.81924971106572e-08 -115.605063224043 51.7441810934994 -2.23416548065859 0.026287926201673 NOC4L essential 6.90271387906148e-06 1 0.00034234149241471 5.71954304184026 -2.23416548065859 0.18737366584025 41.7600563290388 24.9094202474799 1.67647644602502 0.0948468335884357 -4.86580818187039 71.0975485133592 -0.0684384804204059 0.94548919348301 USP18 other 1 1 1 1.67647644602502 -0.0684384804204059 1.25161611110234e-07 263.158985300847 56.4081515747601 4.66526517806688 4.86329630535697e-06 -192.282678278659 128.747387593285 -1.49348799904262 0.136481483618939 NDUFA6 other 0.00119103789132499 1 0.0512202366880196 4.66526517806688 -1.49348799904262 0.00256814070562458 26.6289684811659 57.2738889542309 0.464940812775011 0.642347196497855 -202.423822581392 86.472155559943 -2.34091334107047 0.0199619007227173 SORCS2 other 1 1 1 0.464940812775011 -2.34091334107047 0.0572640668700943 7.78473186589274 3.29119065545889 2.36532388452814 0.018718787492579 4.37696665076886 7.81368697002869 0.560166623971218 0.575828545734206 TMEM121 other 1 1 1 2.36532388452814 0.560166623971218 0.669306406873961 0.734269741698633 8.70823632929831 0.0843189957107881 0.932865294197171 14.714797770791 17.3413818416034 0.848536633654474 0.396890827326811 TMEM106A other 1 1 1 0.0843189957107881 0.848536633654474 9.1821072262652e-17 583.928020001 69.6944361417254 8.37840224165912 3.21294870967242e-15 -3.86114575908814 164.635136979033 -0.0234527442315056 0.981306849429717 SIVA1 other 1.26804900794722e-12 1 4.7127531673475e-11 8.37840224165912 -0.0234527442315056 3.59907051911122e-06 307.686298741324 78.5068996004887 3.91922621205396 0.000112466897431201 -334.832241673304 160.516052167746 -2.08597356558077 0.0379127930557728 BRI3BP other 0.0305777031303689 1 1 3.91922621205396 -2.08597356558077 0.00297623293375779 224.885783980358 65.5740729249077 3.429492388522 0.000699991112356484 246.234886647313 143.393911790694 1.71719205907941 0.0870993429576352 ROBO2 other 1 1 1 3.429492388522 1.71719205907941 1.31400204760561e-15 236.851632849844 55.5610731572255 4.26290601298515 2.79825535424298e-05 -308.504239022805 87.2909923591836 -3.53420474077528 0.000481598359045862 AP3M1 other 1.76444194952481e-11 1 0.277027280070055 4.26290601298515 -3.53420474077528 0.0756832549481123 1.84870941078148 1.73626426343095 1.06476269178536 0.287941695647422 -9.92140927152926 5.68076361012711 -1.74649218880404 0.081871153819328 NT5C1B other 1 1 1 1.06476269178536 -1.74649218880404 0.221716923704828 -1.51372896521891 8.35958481635904 -0.181077050890932 0.856442949073859 -47.1309253069329 27.7927010130749 -1.69580226422615 0.0910760318155694 CA13 other 1 1 1 -0.181077050890932 -1.69580226422615 9.07880866009168e-17 89.0192974143502 11.0374375229405 8.06521416128792 2.34660909421786e-14 -104.743195728426 39.2844696773706 -2.666274906818 0.00812892826335785 UBOX5 other 1.25405584021846e-12 1 3.4004712384311e-10 8.06521416128792 -2.666274906818 0.339516909981258 93.4279617560457 78.5253737598575 1.1897805420419 0.235166344270755 -84.424685619553 192.063661598887 -0.439566156954087 0.660599109234032 MAFF other 1 1 1 1.1897805420419 -0.439566156954087 5.71125439341572e-22 373.379160317686 37.8810656955947 9.85661711098872 8.72016822137482e-20 -15.6824604345045 90.0797274524873 -0.174095336187338 0.861920518950192 BRF1 essential 8.54632107430728e-18 1 1.33401133450592e-15 9.85661711098872 -0.174095336187338 0.0050559789357292 1923.47681292595 608.524243919891 3.16088772492549 0.00175138586476862 72.8907641017948 1466.84436030723 0.0496922278015425 0.960404254459363 SEMA4B other 1 1 1 3.16088772492549 0.0496922278015425 0.176833202854951 -45.0672169811322 81.2262127554021 -0.554835876896587 0.579461211998989 -223.911135827616 124.329122906403 -1.80095484141861 0.0728135124832109 MROH2A other 1 1 1 -0.554835876896587 -1.80095484141861 0.069155464902376 280.073643022736 154.188973135045 1.81643108017482 0.0704090143322067 -325.471326237284 374.43290933195 -0.869238034706881 0.385486143269653 CIB1 other 1 1 1 1.81643108017482 -0.869238034706881 0.162034084293749 5.12967850577316 10.4462973843272 0.491052314236173 0.623791312547585 -36.5956903878459 22.5308561868936 -1.62424765771369 0.105498465786081 ANKS1B other 1 1 1 0.491052314236173 -1.62424765771369 0.05187338258898 51.1621416028224 23.2941370144048 2.19635273765173 0.028913899635773 -33.4130227782022 76.4038138116675 -0.437321399433856 0.662226574686181 SLC24A3 other 1 1 1 2.19635273765173 -0.437321399433856 2.18521679184327e-11 35.918823637491 5.47205371336393 6.56404807390131 2.68405184517296e-10 -30.5493596074199 20.7569856199622 -1.47176281598617 0.142253855482959 EFCAB10 other 2.55735921149418e-07 1 3.53623830601538e-06 6.56404807390131 -1.47176281598617 0.590774776745005 96.3211227841744 98.0480821132657 0.982386607755404 0.326779227279144 11.5387342073258 257.124548258299 0.0448760504801524 0.964238913698402 KRT76 other 1 1 1 0.982386607755404 0.0448760504801524 0.0292706213145206 168.366482231272 68.802669236285 2.44709230179807 0.0150320305510019 17.4814520079934 135.861682771211 0.128670951598855 0.897712761290892 FLRT2 other 1 1 1 2.44709230179807 0.128670951598855 3.64708059061848e-12 141.243745645703 29.6269629071598 4.76740549101538 3.05991158661157e-06 -249.192178098676 60.5077093302275 -4.11835418754133 5.08215761057332e-05 INTS5 other 4.39983802452213e-08 0.767050048163832 0.0327410539767437 4.76740549101538 -4.11835418754133 0.0079936331084377 51.1459993239654 41.530623195524 1.23152496612374 0.219186373885419 -178.255974392014 82.3934730288257 -2.1634720304805 0.0313725648302026 RPS27L other 1 1 1 1.23152496612374 -2.1634720304805 0.0114259270006346 62.9899435242563 47.8000297075826 1.31778042628003 0.188694172364411 -117.812906197623 72.6914629681422 -1.62072547981674 0.10624377600884 MANEAL other 1 1 1 1.31778042628003 -1.62072547981674 0.000127939787602256 81.6381930637356 23.5268529279897 3.47000056971543 0.000607716249275304 -48.3274679258733 55.5761244213038 -0.8695724725157 0.385323995584752 ADSSL1 other 0.935111907584888 1 1 3.47000056971543 -0.8695724725157 0.605986875814121 -4.52119047329356 128.810003000768 -0.0350996845584004 0.97202599723122 -157.938202971924 206.912661795961 -0.763308545746077 0.445940938385598 ANO9 other 1 1 1 -0.0350996845584004 -0.763308545746077 9.80475051414285e-25 311.655020532431 51.3697429057895 6.06689858471741 4.46513285384978e-09 -400.064284351192 81.9051656796987 -4.88448171774291 1.7924492884334e-06 FAF1 other 1.49846002107645e-20 0.0279460768559651 5.62606739585072e-05 6.06689858471741 -4.88448171774291 4.11611150867399e-07 138.406457463555 24.8798169481901 5.56300143814455 6.3794811440027e-08 50.9181970965559 191.597895942827 0.265755512846289 0.790630316020759 FAM43A other 0.00378558775452747 1 0.000761646253782482 5.56300143814455 0.265755512846289 1.08871050900459e-10 97.5498702247629 20.1319566141989 4.84552356704175 2.12790455218364e-06 -67.4411194342352 37.166030704584 -1.8145903169024 0.070692476762775 NSMCE3 other 1.23601304087292e-06 1 0.0230345667773879 4.84552356704175 -1.8145903169024 6.54610230239939e-18 676.053974992609 73.3055716872478 9.2224091488835 8.77902933216786e-18 -36.5221088308594 277.758435744073 -0.131488747526325 0.895486975651174 HSF1 essential 9.26273475789513e-14 1 1.32370204270427e-13 9.2224091488835 -0.131488747526325 2.64454226757438e-12 162.477754543285 25.6989814392863 6.32234218804111 1.06175093863135e-09 -104.935803725054 48.4440652832061 -2.16612299384032 0.031176976373418 C6orf120 other 3.20703640788745e-08 1 1.37072046177307e-05 6.32234218804111 -2.16612299384032 1.61416502952535e-09 100.644405011043 30.1402518615676 3.33920252137561 0.000958513445597068 -168.681846383324 49.5226168736799 -3.40615777259086 0.000759117654513293 PURA other 1.72473533404783e-05 1 1 3.33920252137561 -3.40615777259086 2.45006946288633e-06 37.2668425778008 8.17775501781151 4.55709941134602 7.85336987883492e-06 -26.1242951260532 26.0728932313367 -1.00197146876875 0.317251185426177 INPP5J other 0.0211048983533028 1 0.0813137917254567 4.55709941134602 -1.00197146876875 0.796626407105104 2.3077016484723 4.66553707880842 0.494627222866632 0.621267001542312 -4.91842639565567 12.5132654641935 -0.39305698498363 0.694588706440102 MIXL1 other 1 1 1 0.494627222866632 -0.39305698498363 0.223828717903266 1.24439918533609 6.17096680935812 0.201653845139629 0.840337522871539 32.4696198234898 19.1368617230486 1.69670556716116 0.0908921385096103 MFSD6L other 1 1 1 0.201653845139629 1.69670556716116 1.62361390177498e-10 30.304388700962 8.85515987759252 3.42222942554042 0.000719685099505251 -66.8924668199368 17.4379750560586 -3.83602262332034 0.000156476687573053 LRRC37B other 1.82802689200845e-06 1 1 3.42222942554042 -3.83602262332034 5.61198749656645e-06 127.438659426478 33.3267988603145 3.82390939977831 0.000163039409777594 -160.114770926952 69.177405690074 -2.31455298633621 0.0213851328322818 DDX51 essential 0.0469330514337852 1 1 3.82390939977831 -2.31455298633621 0.0129409101395442 -26.3652484513631 45.5008867475648 -0.57944471714662 0.562768733290826 -185.962578344632 73.0898949746867 -2.5442994330343 0.0115030326050935 SIGIRR other 1 1 1 -0.57944471714662 -2.5442994330343 0.460681856570026 -347.238121955379 314.710939146631 -1.10335574256474 0.270851503886907 -165.72368469271 503.672899557489 -0.32903037832353 0.742386859800457 IFITM2 other 1 1 1 -1.10335574256474 -0.32903037832353 0.026757990627444 -897.819721876651 380.867966610126 -2.35729911829445 0.0191277344380315 141.980301749437 897.68695296277 0.158162376406205 0.874447957477182 TNFAIP2 other 1 1 1 -2.35729911829445 0.158162376406205 4.38496584771417e-06 149.456959112632 33.6531064432056 4.44110440041731 1.30285020303173e-05 -75.1748126733142 88.356763437372 -0.85080994084396 0.395623295033241 ZNF445 other 0.0370398065156416 1 0.132551979656449 4.44110440041731 -0.85080994084396 0.00369406785325715 14.8431980768112 6.27528203050653 2.36534358211357 0.0187623081310273 -36.6008832301572 16.9754247195821 -2.15611001402139 0.0320105398284225 PGBD2 other 1 1 1 2.36534358211357 -2.15611001402139 1.43992965090583e-29 851.630319988965 76.1728375211792 11.1802362587868 3.96298622712272e-24 -131.159984506743 175.244607802089 -0.748439487820747 0.454841778889119 RAB11B other 2.25219396698181e-25 1 6.17631403497075e-20 11.1802362587868 -0.748439487820747 8.27123862845808e-17 193.885943381734 29.4471054644519 6.58421058109737 2.33644777659116e-10 -109.070804214574 56.6890038696017 -1.92402047609556 0.0553915317255556 PRMT3 other 1.14424315186089e-12 1 3.08492477057204e-06 6.58421058109737 -1.92402047609556 0.825740757242755 1.35693848354792 5.53341765831153 0.245226109312336 0.80646695788287 10.294553443695 16.7354428962299 0.615134807457899 0.538981885500847 GP1BA other 1 1 1 0.245226109312336 0.615134807457899 2.03497072010031e-10 254.765769349776 49.914942705434 5.10399803227743 6.47432041793621e-07 -118.663416532831 90.5730039591821 -1.31014111651092 0.191317873019996 PRPF39 other 2.28140567430446e-06 1 0.00727066182934236 5.10399803227743 -1.31014111651092 0.0820378316680666 9.66672877028682 11.5038207624334 0.840305927040713 0.401480374570727 -31.8854679576032 20.1737244219843 -1.58054443942221 0.115152972471874 PPIL6 other 1 1 1 0.840305927040713 -1.58054443942221 2.01106783080959e-32 191.656705273475 14.4490294365117 13.2643307369263 8.6986526303494e-31 -49.7353056695017 61.0999448835171 -0.813999190413653 0.416416968618111 ZNF74 other 3.1654207656943e-28 1 1.37377820991108e-26 13.2643307369263 -0.813999190413653 0.0026803831449855 5.07112068965515 3.23871357606345 1.56578239185292 0.118562204972803 -10.9301332288402 5.63859417861452 -1.93845006088484 0.0536028440749683 KIAA0825 other 1 1 1 1.56578239185292 -1.93845006088484 0.00431586147213453 210.315931798193 63.3046066104469 3.32228479188568 0.00101516388617462 83.3028391422958 145.122536988394 0.57401724687984 0.566430490311365 UBALD2 other 1 1 1 3.32228479188568 0.57401724687984 6.92941020178931e-10 4.63368928832544 1.94007398641678 2.38840854563677 0.0176038386610741 -12.6320485483412 3.26882264436374 -3.86440315754725 0.00013930696431802 CDNF other 7.55582888403106e-06 1 1 2.38840854563677 -3.86440315754725 0.770360381954448 126.705542253477 341.447541297925 0.371083481145708 0.710869619742971 -336.556220450007 759.306223028797 -0.443241751802742 0.65794980995475 NOTUM other 1 1 1 0.371083481145708 -0.443241751802742 4.41003690611367e-05 -5.05145321179759 7.72861905968243 -0.653603596294362 0.514085668240892 -53.4992020378726 12.6348862168052 -4.23424486139933 3.43534591352412e-05 RBM11 other 0.339440540663569 0.521038914704203 1 -0.653603596294362 -4.23424486139933 5.44621547432975e-08 99.2008991919991 16.8045862064476 5.90320392143529 1.07086629094491e-08 76.3348153699775 53.8319470418638 1.41802070266219 0.157342095325421 ZBTB37 other 0.000530298000735487 1 0.000132798128740078 5.90320392143529 1.41802070266219 0.768393115685005 -2.06232871733532 6.73255268406137 -0.306321957526997 0.75962620251626 -14.8654000285098 21.0087197012828 -0.707582386736401 0.479894043603583 NUPR2 other 1 1 1 -0.306321957526997 -0.707582386736401 3.337429753225e-11 289.491922738057 41.3656903253253 6.99835831243995 2.06024755979617e-11 63.624448215368 92.1349814870677 0.690556911050104 0.490439441903346 CCDC137 other 3.8757571724202e-07 1 2.80935357253806e-07 6.99835831243995 0.690556911050104 0.68257894767853 -13358.2853419761 20276.181285566 -0.658816625963268 0.510574963908951 -26483.3195418046 30875.3474694886 -0.857749684209245 0.391791443267379 SFTPA2 other 1 1 1 -0.658816625963268 -0.857749684209245 0.153350132670974 23.5865054859916 13.5473647595235 1.74104011404955 0.0828327576577072 -31.6303820255443 54.6111732507475 -0.579192501144651 0.562949446922842 RGPD2 other 1 1 1 1.74104011404955 -0.579192501144651 0.00112678704106407 91.6338441737406 31.3768078477618 2.92043233391816 0.00379060997761224 -18.0533442722923 57.436568471849 -0.314317946782296 0.753522303226054 ARL15 other 1 1 1 2.92043233391816 -0.314317946782296 6.23511469495028e-07 55.1744061741476 12.358345737999 4.46454625431777 1.17997653624016e-05 -61.4923984122357 36.4305796735121 -1.68793357018542 0.0925786837820283 C12orf56 other 0.00564651986774697 1 0.120499203880845 4.46454625431777 -1.68793357018542 2.71227036678286e-06 184.28292346587 65.7617769309274 2.80228017043138 0.00545168827027555 -206.183721628825 107.157042081446 -1.92412666142943 0.0554177274861523 CDK10 other 0.0232794165580973 1 1 2.80228017043138 -1.92412666142943 0.00509682375194874 1.41161609394429 2.57855104086708 0.547445472892251 0.584528325139679 18.4738580702991 5.71955705448614 3.22994558744879 0.00139257908077677 TMEM105 other 1 1 1 0.547445472892251 3.22994558744879 0.0300495125202685 91.06792802005 38.2385000620011 2.3815768890618 0.0179371300125271 8.92527652577223 74.2591702495942 0.120190900272293 0.904421980110643 SOCS1 other 1 1 1 2.3815768890618 0.120190900272293 5.83849189113703e-05 206.096627515873 50.5867980125383 4.0741188533971 6.06496563893031e-05 -89.9910388732358 160.540853782766 -0.56054914841182 0.575566347434576 TCN2 other 0.444367617834439 1 0.581630204773417 4.0741188533971 -0.56054914841182 1.34183529877134e-08 252.400361196296 56.2442348279153 4.48757747293636 1.06584552442127e-05 -371.637991653872 147.534164751497 -2.51899614085897 0.012344853851818 GAS2L1 other 0.000135619293646819 1 0.109227849342692 4.48757747293636 -2.51899614085897 0.00221106641065614 60.9191336743501 23.8369898542052 2.55565547692688 0.0111410309946163 -82.3478907510981 48.8488066828155 -1.68577077605597 0.0929825001255491 ATP6V0A2 other 1 1 1 2.55565547692688 -1.68577077605597 0.0379383247033177 6.1229355454368 4.78213561065149 1.28037681152305 0.201519699516746 -15.3363589458445 8.85831639503103 -1.73129500707914 0.0845499976481194 PRKN other 1 1 1 1.28037681152305 -1.73129500707914 0.0699377313689563 19.9122476294607 15.7516594965908 1.26413649519089 0.207291815843589 -31.6806939643575 28.1429382513893 -1.12570669350041 0.261308148806065 HS6ST3 other 1 1 1 1.26413649519089 -1.12570669350041 1.69502992516545e-10 614.881313076155 90.451694050447 6.79789714865066 6.83018223104238e-11 178.60395107254 200.81728962319 0.889385328363255 0.374590683900189 HGS essential 1.90690866581113e-06 1 9.17634982740544e-07 6.79789714865066 0.889385328363255 0.00180652962283093 22.1224043104548 37.5461445124425 0.589205751954733 0.556210507017713 -176.489927822995 68.7701406090958 -2.56637439243001 0.0108105369965108 TNFAIP8L1 other 1 1 1 0.589205751954733 -2.56637439243001 8.69459313710034e-17 131.779584689703 23.0282027579055 5.72253015465846 2.77537216223586e-08 -162.047796432153 44.9791774982197 -3.6027292059435 0.000374537112293889 RAD51D essential 1.20202750120412e-12 1 0.000337179963990034 5.72253015465846 -3.6027292059435 0.0176873447625588 20.1506884093172 24.3626097759951 0.827115345794028 0.408915842577428 -110.459494659351 51.9500190027172 -2.12626475947148 0.0344056451940756 MAPK11 other 1 1 1 0.827115345794028 -2.12626475947148 2.99891302633268e-09 70.2811734082328 38.0442085328595 1.84735538255526 0.0657854986063182 -250.70176395871 59.2735992883727 -4.2295687619545 3.20567334489699e-05 SP140L other 3.15395682979408e-05 0.486589157021914 1 1.84735538255526 -4.2295687619545 5.18362444945618e-14 199.063716630145 24.3915314314304 8.16118156376336 1.24220631866501e-14 -5.68202066571749 104.281520153693 -0.0544873210262296 0.956586908876338 MRPL30 other 6.66717776689054e-10 1 1.80765863492133e-10 8.16118156376336 -0.0544873210262296 2.52430869225066e-10 77.1521180640509 11.4795563615024 6.72082749842028 1.07612795727602e-10 9.70559570964708 28.0949530152617 0.345456911936276 0.730020887297153 TARSL2 other 2.81712850055173e-06 1 1.43630798457631e-06 6.72082749842028 0.345456911936276 0.00490698170138596 107.186864574853 33.6987944389223 3.18073291224481 0.00164109617174561 -44.8860775349157 91.3925496204405 -0.491134974583056 0.623731435665452 SMYD3 other 1 1 1 3.18073291224481 -0.491134974583056 0.361797183360755 37.9494913451399 172.629007978445 0.219832644522168 0.826165782595129 -545.698495854396 439.542674409336 -1.24151425475971 0.215481465673068 METTL7A other 1 1 1 0.219832644522168 -1.24151425475971 9.42541780609911e-05 100.889684027619 24.3740337542405 4.13922804263231 4.65203771619966e-05 46.0601122702499 36.4185341045563 1.26474371917368 0.207045759086778 IFNLR1 other 0.700911987975549 1 0.450317250928127 4.13922804263231 1.26474371917368 0.000147764310355245 22.6502898185484 7.6663370446781 2.95451265533284 0.00340676853304523 -15.5658683530746 12.3824666956662 -1.25708945847781 0.209803579956416 SH3BGR other 1 1 1 2.95451265533284 -1.25708945847781 0.356637080073535 19.700394194197 65.8379556611615 0.2992254846974 0.76499905684827 -203.453985174606 162.398052371155 -1.25281049990439 0.211362645653434 FAM174B other 1 1 1 0.2992254846974 -1.25281049990439 0.209545909182548 -3.11129649690033 1.87614177605841 -1.65834828508369 0.0984214755762903 2.55109004077103 8.41416658135694 0.303189866293284 0.761981271146476 KPNA7 other 1 1 1 -1.65834828508369 0.303189866293284 0.111854121505827 -53.7199088460741 43.8190182535559 -1.22594962158274 0.221277973359253 -142.503408855491 67.8823329935928 -2.09927093797648 0.0367146185842129 GPRIN3 other 1 1 1 -1.22594962158274 -2.09927093797648 0.803405642072412 -1080.3622663175 2394.19550386721 -0.451242291856472 0.652174479991076 1984.20260625178 6450.15309874826 0.307621009280669 0.758606144793635 KRT6B other 1 1 1 -0.451242291856472 0.307621009280669 2.73664770580881e-06 115.062274290493 24.3219314289311 4.73080333388432 3.60364565009874e-06 -36.6447979927223 53.5150825238372 -0.684756451163083 0.494082839325149 PARPBP other 0.0234859106112512 1 0.0383319787801003 4.73080333388432 -0.684756451163083 0.819573685978027 3.29529141870712 5.31068872357605 0.62050170707203 0.535445176332123 1.39590526052787 14.2229756957462 0.0981443890778326 0.92188966030399 STAC3 other 1 1 1 0.62050170707203 0.0981443890778326 0.00812766678921866 27.6610386004638 8.86504100871288 3.12023808725505 0.00200148088518059 20.7091372627362 35.3046440775144 0.58658394111742 0.557969668668313 ROR1 other 1 1 1 3.12023808725505 0.58658394111742 6.17420962864769e-10 82.774200582573 12.27645999542 6.74251377135213 9.47244747164162e-11 4.39494896959398 94.9092272438953 0.0463068670688884 0.963100024596552 SDHAP1 other 6.75149822892625e-06 1 1.26722402275622e-06 6.74251377135213 0.0463068670688884 0.456731213683638 -561.363362216491 447.748352263035 -1.25374746635966 0.211022305483315 -128.227691726562 1499.60362589943 -0.0855077231822865 0.931921362832106 MUC1 other 1 1 1 -1.25374746635966 -0.0855077231822865 2.14552984779649e-10 246.916635213745 37.3289359533589 6.61461755894295 2.01336387018155e-10 22.1837025853771 82.9015637937117 0.267590882128327 0.789220070187489 FAAP100 other 2.40299342953207e-06 1 2.66529109134633e-06 6.61461755894295 0.267590882128327 0.295499205164804 -65.2473353268642 68.1239620314009 -0.957773643535137 0.339027438112456 -171.395633930999 109.775340837868 -1.56133092024866 0.119608397474878 IRF7 other 1 1 1 -0.957773643535137 -1.56133092024866 0.000331653115498534 39.0102495126932 11.8984240038011 3.27860643562802 0.00117898271158707 -61.5281541963896 41.172892517366 -1.49438502943261 0.136234191656061 L3MBTL1 other 1 1 1 3.27860643562802 -1.49438502943261 0.849206241250337 -18.3956655268132 69.8589533094074 -0.263325810871202 0.792501056188556 -95.3807139421894 169.214723696279 -0.56366675345218 0.5734505337154 SV2B other 1 1 1 -0.263325810871202 -0.56366675345218 0.0332013513313077 8.52723201120616 5.70043134235399 1.49589241569303 0.135836803383411 -8.87138012385729 8.85419085121984 -1.00194137137162 0.317259153664467 FAM131C other 1 1 1 1.49589241569303 -1.00194137137162 0.0460532218088298 -5.31193920366195 17.8367199287391 -0.297809195013663 0.766075306149141 -58.8770135852821 28.7556283561074 -2.04749528878847 0.041566441475209 LMNTD2 other 1 1 1 -0.297809195013663 -2.04749528878847 0.460451132728852 0.446253003431076 1.74903882979904 0.255141850385534 0.79880850372078 -4.08867207970916 3.89077177140812 -1.05086402388219 0.294264171261759 PDE6G other 1 1 1 0.255141850385534 -1.05086402388219 0.325391230615658 8.62051386071683 31.1769983673829 0.276502367518983 0.782376158286971 -49.1954208924947 47.6296103883602 -1.03287472837521 0.302597171341736 PRKG1 other 1 1 1 0.276502367518983 -1.03287472837521 0.239120527418155 428.239104445167 379.932585275322 1.12714497529829 0.260681892519398 -536.493463270903 837.638766965081 -0.640483087016994 0.5224017635673 DLK1 other 1 1 1 1.12714497529829 -0.640483087016994 1.06169536942622e-06 90.7916244622337 19.3092909031303 4.70196574890874 4.10089909570493e-06 -77.8443193576017 59.884949006352 -1.29989789837418 0.194736461975986 TLCD2 other 0.00943210166198254 1 0.0434654295153766 4.70196574890874 -1.29989789837418 0.607792151503585 16.2265828708964 53.6055721146271 0.302703286818735 0.762349067285563 -179.892944960739 205.369163590611 -0.875949153298121 0.381836292409487 LSAMP other 1 1 1 0.302703286818735 -0.875949153298121 0.00102071947058189 1781.77964171816 494.949536534816 3.59992183080431 0.000379127280615202 559.210241417607 1204.56739918432 0.46424155410173 0.64285157694688 AHNAK2 other 1 1 1 3.59992183080431 0.46424155410173 0.0649256025265745 267.241913060862 115.479873549705 2.31418605551065 0.0214027904269158 133.636099096809 222.718605688134 0.600022161075915 0.548991010637624 OLFML2A other 1 1 1 2.31418605551065 0.600022161075915 3.29085991692777e-07 260.43288110071 85.8407048836162 3.03390892996287 0.00264668933192406 -794.045005757476 232.314388618648 -3.41797600432286 0.000727107663367344 SP1 other 0.00304931079902528 1 1 3.03390892996287 -3.41797600432286 7.44680039357719e-39 320.572159292013 21.0548795672337 15.225551790422 6.77937532779408e-38 2.93034921771065 83.2807061484298 0.0351864117540975 0.971957992514248 MRPL40 essential 1.18054126639379e-34 1 1.07636142079387e-33 15.225551790422 0.0351864117540975 0.00423580869493337 -5.79665565802129 14.1863452327533 -0.408608106098957 0.683149972971667 -108.272661532613 33.1962772372819 -3.26159047168742 0.0012497460100159 FAM212A other 1 1 1 -0.408608106098957 -3.26159047168742 0.101575717660307 73.8032064592975 46.65328380535 1.58195094620186 0.114867158451874 -28.4176686237098 85.1334792679544 -0.333801330194274 0.738796487381471 PDIA2 other 1 1 1 1.58195094620186 -0.333801330194274 2.038757191804e-58 909.29805576901 45.3176088402239 20.0650051721599 5.01503351735467e-55 218.019362309076 124.35182129405 1.7532462334712 0.080720352478246 PCGF3 other 3.24937121229721e-54 1 7.99245891660813e-51 20.0650051721599 1.7532462334712 5.87142452845952e-07 54.6271696189747 10.5137069341269 5.195804863236 4.14403057024141e-07 -96.6053267788358 76.0122734034933 -1.27091747757667 0.204902720791759 LMLN other 0.00532714347467132 1 0.00471673559504878 5.195804863236 -1.27091747757667 1.11307338605226e-07 6912.16886318457 1206.98258807615 5.72681738035847 2.7411573283111e-08 2785.65043287703 2681.87074329163 1.03869675294568 0.29988199952162 P4HB other 0.00106309639101852 1 0.000333215084829497 5.72681738035847 1.03869675294568 3.53832955125203e-11 366.907352578807 145.487427034666 2.52191794203208 0.0122451739693758 -756.846177758396 232.842475772877 -3.25046439764131 0.00129775526644413 PSMD13 essential 4.10446227945235e-07 1 1 2.52191794203208 -3.25046439764131 2.02003368845036e-05 1025.88184526238 220.173234999055 4.65943031298416 4.96884857479692e-06 -460.117998313337 735.470769028233 -0.625610177439526 0.53209522021337 PBX1 og 0.161138087327685 1 0.0522772558554384 4.65943031298416 -0.625610177439526 0.332256444716806 320.438627174853 669.255935745832 0.47879833417951 0.632465355869886 -2094.69814995685 1792.38727852556 -1.16866381225378 0.243558587416965 NDUFA4L2 other 1 1 1 0.47879833417951 -1.16866381225378 0.0924496769066437 -7.37996378850529 4.81366568432119 -1.53312761468727 0.126410972257029 -19.0783104156982 9.19941711521321 -2.07386078669572 0.0390366601224782 SHC4 other 1 1 1 -1.53312761468727 -2.07386078669572 0.84206030918872 -36.1186097335728 75.4989634009942 -0.478398750215122 0.632749311276257 -95.7295166738361 197.905683097453 -0.483712823075913 0.628977450047734 KRT79 other 1 1 1 -0.478398750215122 -0.483712823075913 0.0513887971282719 1113.35206790872 532.039502389095 2.09261166306124 0.0373105433420061 -119.082170166289 967.757749071553 -0.123049565121575 0.90215872026557 ZFP36L1 other 1 1 1 2.09261166306124 -0.123049565121575 1.07719018031687e-21 493.296062457422 54.4564427464811 9.05854362823393 2.93411179024781e-17 -579.418584933828 190.248040092885 -3.04559555331522 0.00255537116653815 UBE2L3 essential 1.60684459197868e-17 1 4.40234133008782e-13 9.05854362823393 -3.04559555331522 0.174092760960071 8.90613790354723 5.12672576835473 1.73719802969009 0.0834842112598593 -8.08734954165005 23.0521672127157 -0.350828165830283 0.725988827256889 NTF3 other 1 1 1 1.73719802969009 -0.350828165830283 1.23754493753615e-20 210.053127839472 46.2626463433481 4.54044773575032 8.44008687513787e-06 -448.982295917552 74.4269559038764 -6.03252263195366 5.25593748293605e-09 BRWD1 other 1.82364621995327e-16 8.35694059786832e-05 0.0871860974201742 4.54044773575032 -6.03252263195366 1.43175409937652e-07 35.889900365979 7.23568527040326 4.96012458042951 1.24262339138099e-06 -22.1589410854682 19.2619825963371 -1.15039773162717 0.250990468516756 PMEL other 0.00135715971079901 1 0.013688739279453 4.96012458042951 -1.15039773162717 0.7896403324848 -2.54090241939303 4.14755791165641 -0.61262614615989 0.540635404675408 -5.44512452061931 10.6358438205345 -0.511959804271143 0.609094550987642 SYN3 other 1 1 1 -0.61262614615989 -0.511959804271143 0.000143618290910296 44.1402835786809 13.2088774833852 3.34171345250214 0.000950229438280716 -10.5213496889768 20.0872809976917 -0.523781675090114 0.600860060874902 POU3F1 other 1 1 1 3.34171345250214 -0.523781675090114 0.0628664084698003 -3.10768574443718 3.23057660296776 -0.961960085262277 0.336933555759081 -12.2948110559759 5.31363492420882 -2.31382306676 0.0214313698276737 SNAI3 other 1 1 1 -0.961960085262277 -2.31382306676 2.35647093343637e-06 7.42477765081918 5.70752669404303 1.30087480073785 0.194406336386338 -50.1273470191311 11.6885614987636 -4.28858136430507 2.50322880933075e-05 ZBTB3 other 0.020331631213689 0.381266779949167 1 1.30087480073785 -4.28858136430507 0.937288880821007 -0.880307010039459 5.25065747879072 -0.167656529414713 0.866978080560585 -3.61969067778977 10.0662630303058 -0.359586339726293 0.719435513696467 MORN5 other 1 1 1 -0.167656529414713 -0.359586339726293 0.00625491170688383 19.970699616592 16.8025629455248 1.18855079914526 0.235656969462851 -92.104144458252 34.8775686013969 -2.64078455441883 0.00875145317455919 EP400NL other 1 1 1 1.18855079914526 -2.64078455441883 3.4729377143925e-13 1013.80046653049 126.93768912999 7.98659935814897 3.89651747070044e-14 916.81729168069 435.369104546607 2.10583911928124 0.0361314843376681 PRAME other 4.34950719350517e-09 1 5.62384366546195e-10 7.98659935814897 2.10583911928124 3.50280275724025e-06 38.6720092172046 8.76826622145375 4.41045107898114 1.4951305332687e-05 -10.8873705159643 15.7996370141083 -0.689089914296285 0.491362831586754 C6orf201 other 0.0297913374503283 1 0.151350955743009 4.41045107898114 -0.689089914296285 6.09898167762319e-08 38.0745830781719 6.8885478935064 5.52722920226243 7.66448256154882e-08 -1.14866660604882 22.1269051879694 -0.0519126645272275 0.958636668872252 MYBL1 other 0.000591906171813331 1 0.000911766845521848 5.52722920226243 -0.0519126645272275 1.54316365195011e-13 310.438638342991 46.5360866957981 6.67092272653475 1.42516874753132e-10 -362.564545125609 147.975940545487 -2.45015874735501 0.0149120819368801 DRG1 other 1.95534266338598e-09 1 1.89632953546518e-06 6.67092272653475 -2.45015874735501 9.38024653480763e-17 438.104867589194 57.8311978424977 7.57558003177395 5.56518044183256e-13 -512.137008709491 175.312711085744 -2.92127710271395 0.00377736047902593 ANKFY1 other 1.29513063906089e-12 1 7.88586068607674e-09 7.57558003177395 -2.92127710271395 3.70060210056789e-18 334.90253257894 44.8925528885405 7.46009106255192 1.26155171656208e-12 -408.433807322886 137.922738271583 -2.96132321937114 0.00334310726825016 YTHDF3 other 5.25633522364663e-14 1 1.77336324797132e-08 7.46009106255192 -2.96132321937114 5.88162343307337e-11 39.138169623907 5.96511579199181 6.56117517055582 2.72900881986852e-10 -24.7465054958225 22.5378255189862 -1.097998805385 0.273186844675245 ZNF696 other 6.75974981163122e-07 1 3.59492331841281e-06 6.56117517055582 -1.097998805385 0.193159781165549 -27.1781290124424 19.6832177927353 -1.38077672556534 0.168533374323152 -59.3920183890613 33.5774081942316 -1.76880889809907 0.0780982064906207 ADARB2 other 1 1 1 -1.38077672556534 -1.76880889809907 0.731722329615323 3.9496291595605 18.6262693812671 0.212046174073523 0.832229819421716 -18.4114544084402 34.1764282640762 -0.538717921784501 0.590522119937722 SRL other 1 1 1 0.212046174073523 -0.538717921784501 0.280862568943219 21.7792540103433 16.1786423791995 1.34617315222595 0.179375800986404 -1.88848911137035 28.8386135345267 -0.065484740072867 0.947836515644304 C11orf87 other 1 1 1 1.34617315222595 -0.065484740072867 0.55684733407585 182.659761031709 188.037610310826 0.971400140268603 0.332218472929583 58.6545793432969 269.387536715403 0.217733084679649 0.827801541435059 IFIT1 other 1 1 1 0.971400140268603 0.217733084679649 0.0251735292770459 64.2013090125618 23.8425590715977 2.69271888222105 0.0075441494264281 20.0719480904491 55.2646258229758 0.363197032306774 0.716750563084072 KCNQ5 other 1 1 1 2.69271888222105 0.363197032306774 0.350935230755219 23.5020246768176 16.9025418349465 1.39044321891436 0.165543622563784 12.3289936248333 29.7358710006001 0.414616865421042 0.678752849523882 ADAMTSL5 other 1 1 1 1.39044321891436 0.414616865421042 0.0236055184861135 3.5307237370785 6.29856660882077 0.560559879153129 0.575565923445207 -15.0219553798016 9.09021758187972 -1.65254079393502 0.0995953687436066 KCNIP4 other 1 1 1 0.560559879153129 -1.65254079393502 8.81209570454877e-06 558.318761006245 143.122295156659 3.90099083022053 0.000120698116074606 -405.151834318737 277.343183353481 -1.46083213374803 0.145211453039764 MORF4L1 other 0.07254998393555 1 1 3.90099083022053 -1.46083213374803 1.58450009563438e-26 81.7436272867022 6.74254373437905 12.1235590760659 3.3092197303334e-27 -20.4670712696562 51.8962508112106 -0.39438439096712 0.693614463910462 WDR53 other 2.44583434762122e-22 1 5.19613682056951e-23 12.1235590760659 -0.39438439096712 8.60582539449616e-23 185.795505259802 20.9120252785923 8.88462512762937 8.84229848763073e-17 -163.159837567026 55.6182502001572 -2.93356653580168 0.00363542697198722 DMWD other 1.29689788695057e-18 1 1.32130466300666e-12 8.88462512762937 -2.93356653580168 1.15446537949791e-11 424.369618962901 57.8738393958595 7.33266746068452 2.67679634816549e-12 147.776006215909 219.030924090838 0.674681015154838 0.500460044089532 SLC52A2 other 1.36596343702193e-07 1 3.73546930386494e-08 7.33266746068452 0.674681015154838 9.99099044608968e-09 86.1602306101617 17.58018305152 4.90098597708925 1.64061828156386e-06 -31.8864001900652 28.0134860874505 -1.13825177239721 0.256016939288537 PIGP other 0.000101838165616992 1 0.0179204734895221 4.90098597708925 -1.13825177239721 0.0746087025901723 -81.6522461081371 36.6938901215581 -2.22522730181081 0.0269047390213522 -115.056992154889 96.2346160541986 -1.19558841581588 0.232921965123086 IKZF1 other 1 1 1 -2.22522730181081 -1.19558841581588 2.05275079003588e-11 292.226472602955 44.0082735896204 6.64026213179783 1.74440129763903e-10 -51.9133571723343 97.8649776604958 -0.530458989654372 0.596234634392997 PCYT2 other 2.40561865084305e-07 1 2.31499496209676e-06 6.64026213179783 -0.530458989654372 0.164610904794642 4.79267133869365 8.57883370475355 0.558662343115244 0.576851798851007 -32.9288311151033 23.2961780187165 -1.41348641346438 0.158656158649157 NAT8L other 1 1 1 0.558662343115244 -1.41348641346438 5.65764188573012e-25 95.8283931682408 8.88000293570182 10.791482149512 9.90128070292485e-23 -66.2042270011685 38.7958870592075 -1.70647540292435 0.0890955360333525 GNB1L other 8.66298125542997e-21 1 1.53400541930415e-18 10.791482149512 -1.70647540292435 9.46904297262251e-06 69.6386161540467 14.1904837879936 4.9074166317689 1.59808147490464e-06 32.8856282260962 39.1567616827824 0.839845452300421 0.40173808389489 DNAH14 other 0.0777692499341487 1 0.0174782170910321 4.9074166317689 0.839845452300421 0.536345569674849 22.7195845862258 40.061333093145 0.567120034008889 0.571098644949363 -121.942119607004 132.884776599509 -0.917653042940469 0.359610520104743 CCDC190 other 1 1 1 0.567120034008889 -0.917653042940469 0.112543028068234 -100.674312242026 48.5791868179507 -2.07237541087916 0.0392048151464068 -121.550267326863 97.3604163204449 -1.24845673345111 0.21297406593924 EVI2B other 1 1 1 -2.07237541087916 -1.24845673345111 8.95661490026707e-09 32.8743831435143 5.37314722259855 6.11827329153577 3.31132639308973e-09 -0.474666863881396 23.5424094857044 -0.0201622040500836 0.983928870119739 ZNF829 other 9.155451751053e-05 1 4.19644393796261e-05 6.11827329153577 -0.0201622040500836 0.347672269732099 4.28444961951216 5.73785735794388 0.746698523897683 0.455897674220722 -8.44542310104153 11.9759564250622 -0.705198215598691 0.481297063854622 TMPRSS11B other 1 1 1 0.746698523897683 -0.705198215598691 1.58901460427815e-08 57.5276778260746 17.5859008710525 3.27123860460107 0.00120892639483652 -76.6409510924324 29.0560049769428 -2.63769747951415 0.00882766496084176 THNSL1 other 0.000159823088898296 1 1 3.27123860460107 -2.63769747951415 0.0150778327447202 161.745689840751 74.496201285626 2.17119379309828 0.0307811475478049 -90.5495924486329 133.539265967053 -0.678074660609361 0.498300777690276 TRIM69 other 1 1 1 2.17119379309828 -0.678074660609361 3.02189903662955e-14 442.926252771752 137.007674032668 3.23285725342758 0.00137724014952058 -1203.81924751624 253.575898083261 -4.74737250904251 3.34163793303227e-06 ATP6V0C other 3.91426582214625e-10 0.0518989787379241 1 3.23285725342758 -4.74737250904251 0.72778442193069 65.9235020945081 401.431402015898 0.16422108924079 0.869679514944996 438.452240776894 642.46294957218 0.682455293443555 0.495534023139201 IFITM1 other 1 1 1 0.16422108924079 0.682455293443555 6.04942800620948e-13 2129.6023904182 332.219989403611 6.41021750148503 6.65583350812824e-10 -962.690000503249 622.213740353169 -1.54720144874465 0.123012565268711 LAMP1 other 7.5170192405159e-09 1 8.65058681051428e-06 6.41021750148503 -1.54720144874465 6.21723011681948e-07 25.6209575837956 6.45550236887756 3.96885573264074 0.000106824421563918 -23.8295580139575 16.0406226248634 -1.48557562703464 0.139265492260992 POMK other 0.00563156703981509 1 0.998915166044197 3.96885573264074 -1.48557562703464 0.194904368403953 107.404804744289 96.6270983286866 1.11153917070904 0.268615227524664 -75.7459228765132 159.017787648214 -0.476336163373631 0.634723245170537 LINC00839 other 1 1 1 1.11153917070904 -0.476336163373631 0.0265223598052877 110.24216674398 40.9406218009624 2.69273308255882 0.00752518119068494 114.157635052504 97.7805241094018 1.16748847577027 0.244031830015719 KLHDC8B other 1 1 1 2.69273308255882 1.16748847577027 4.72392947582822e-10 92.2423868436312 23.7595351140521 3.88233129986943 0.000130030072429839 -117.884458273218 37.8052051486661 -3.11820707782557 0.00201558144300124 SETD4 other 5.19726720930621e-06 1 1 3.88233129986943 -3.11820707782557 6.6369804049699e-07 211.619193001811 65.1713303509412 3.24712096350132 0.0013130756927291 -337.236986039929 124.914696726837 -2.69973826040181 0.00737754314006811 PTCH1 ts 0.0059971754939308 1 1 3.24712096350132 -2.69973826040181 0.12301352863048 7.15022599793055 15.3002116406115 0.467328568119386 0.640638979999317 -85.90031139693 47.4513744953668 -1.81028078344321 0.0713557183105934 RTN4RL1 other 1 1 1 0.467328568119386 -1.81028078344321 0.173794133966408 21.7077614935322 26.8353617960474 0.808923749883244 0.419273880930365 -32.5825300701137 38.0110842754813 -0.857184968310171 0.392105679992221 RNPC3 essential 1 1 1 0.808923749883244 -0.857184968310171 0.0303556103667906 -1.03242309853291 20.1385546901877 -0.0512659977051852 0.959153230984435 -96.8002316641754 41.2677281865126 -2.34566417677948 0.0197510002338774 ZNF267 other 1 1 1 -0.0512659977051852 -2.34566417677948 2.06808368739007e-07 363.27295491046 85.9906980313134 4.22456106564195 3.30712902318552e-05 -267.532722008278 158.51459217117 -1.68774822774289 0.092649569843462 IRS2 other 0.00194172377409054 1 0.324826212657282 4.22456106564195 -1.68774822774289 1.31997562454549e-10 593.931071717808 175.578897246727 3.38270191367705 0.000824089121595283 -1449.95464770989 351.982961520062 -4.11938873815983 5.05558437192995e-05 BICD2 other 1.49223244354867e-06 0.763089905099107 1 3.38270191367705 -4.11938873815983 0.510263978679004 0.25202884310454 5.03859405456294 0.0500196761984234 0.960143419344716 -21.9204414499188 19.0228666452374 -1.15232061806031 0.25020109680699 LCE3E other 1 1 1 0.0500196761984234 -1.15232061806031 0.000437878580030568 39.145658977672 28.3242633599419 1.38205391187806 0.168141345293558 -149.129433142124 53.2280285807504 -2.80170874478068 0.00546550227275938 RASA3 other 1 1 1 1.38205391187806 -2.80170874478068 4.38491033185392e-17 150.900684463411 16.5057884481419 9.14228877569302 1.88178611032026e-17 -118.722957952627 119.333981070738 -0.994879722333674 0.320726921278351 LRCH3 other 6.10598763710659e-13 1 2.82945359547754e-13 9.14228877569302 -0.994879722333674 0.0223528294834129 20.5829153991614 16.4726157973534 1.2495231875965 0.212543974741317 -110.622682634949 47.0780898778487 -2.34976998688725 0.0194974492893555 LEMD1 other 1 1 1 1.2495231875965 -2.34976998688725 0.00236197256020736 1.04521432160481 0.344736617757388 3.03192137929598 0.00267365718335864 -0.214444552831759 0.64491406155047 -0.332516478732379 0.739765187737329 ATP4B other 1 1 1 3.03192137929598 -0.332516478732379 7.56801989795151e-11 809.06414472203 136.421327579579 5.93062799693163 9.20531065350092e-09 -291.46468517773 313.926644274922 -0.928448382745362 0.354004292475198 NDUFA13 other 8.65781476325653e-07 1 0.000114504859218898 5.93062799693163 -0.928448382745362 6.94462118744784e-18 47.7397071225946 5.30350291401246 9.00154254586358 4.16027986243432e-17 -23.5398779350591 21.6389452637856 -1.08784775080766 0.277636042827619 ZNF566 other 9.81899989693251e-14 1 6.2329312898991e-13 9.00154254586358 -1.08784775080766 2.92075756875044e-12 81.1126849990172 11.1287346135496 7.28858112046805 3.49093816920669e-12 -26.9474108311503 45.7355919447875 -0.589200001252449 0.556221599369601 ZNF529 other 3.53411665818803e-08 1 4.85868774390187e-08 7.28858112046805 -0.589200001252449 3.61904811746423e-11 21.1023548452985 4.21056568851505 5.0117624106562 9.70922750768708e-07 -37.2101749414607 11.5664413787478 -3.21708066664574 0.00145108273505003 ZNF284 other 4.19628629219977e-07 1 0.0107772425335327 5.0117624106562 -3.21708066664574 0.858091934319035 1.00114319297245 1.81026128545371 0.55303795149192 0.580691662102326 0.740134662820254 2.96795222070261 0.249375531606449 0.803258524597201 DLEU7 other 1 1 1 0.55303795149192 0.249375531606449 0.894831578261781 -3.44827247691339 7.37875125959296 -0.467324667223382 0.640641766930999 -4.25206211750142 19.8789427283946 -0.213897800079069 0.8307870080424 KRT73 other 1 1 1 -0.467324667223382 -0.213897800079069 0.0670346002515095 7.0583397685238 4.09897206227448 1.7219780133381 0.0862187506325695 -1.92498355451323 5.94163104646066 -0.323982344151093 0.746202228124025 MATN1-AS1 other 1 1 1 1.7219780133381 -0.323982344151093 0.0138419050514914 77.2168972954401 26.579931515876 2.90508262782088 0.00397325376295922 -20.0586490561718 74.4076099703157 -0.269577924410877 0.787689380515379 AIDA other 1 1 1 2.90508262782088 -0.269577924410877 0.0047252041929281 105.758135335647 40.1570614728195 2.63361240730301 0.00893914300434095 -26.5058590865846 71.1431552689454 -0.372570755210158 0.709762408348572 C15orf41 other 1 1 1 2.63361240730301 -0.372570755210158 0.770398760616895 -3.29847014425652 13.2877241374316 -0.248234393650957 0.804139676959408 -21.5343067619449 29.961906573691 -0.718722845923755 0.472926400616071 CD300LF other 1 1 1 -0.248234393650957 -0.718722845923755 0.693285935909984 5542.28400736874 11877.2076225763 0.466631904020431 0.641136781097903 -16744.6891023661 31998.1419343129 -0.523301919740849 0.601190216861717 KRT5 other 1 1 1 0.466631904020431 -0.523301919740849 0.00392367421924195 48.7907482002957 30.5904700238078 1.59496562695255 0.111885443734712 -241.104932659126 104.05147234651 -2.31716983164067 0.021239978627491 GSAP other 1 1 1 1.59496562695255 -2.31716983164067 1.49772316206745e-09 29.0461977948115 14.379429174414 2.01998267403373 0.0443913922970253 -93.830862298515 23.6986502417752 -3.95933360513136 9.66220931733229e-05 CYP2R1 other 1.60361218962562e-05 1 1 2.01998267403373 -3.95933360513136 0.00976529652580435 5.50760879501418 3.97995822259304 1.3838358311776 0.167555869746175 -10.0994628136948 6.35189541438797 -1.58999198740238 0.113011149377203 LRRC70 other 1 1 1 1.3838358311776 -1.58999198740238 1.85205193026369e-06 96.5535143414339 19.9488173443765 4.84006207859997 2.17848145595199e-06 -62.5742415202545 77.8603884203771 -0.80367235239579 0.422288003779723 ANKRD46 other 0.0161554489876902 1 0.0235602769461208 4.84006207859997 -0.80367235239579 8.8019897954804e-10 49.8592019113612 54.5294406454703 0.914353811833992 0.361343770727009 -451.043551108704 91.8430571488372 -4.91102501496396 1.56830537607793e-06 PIP5K1C other 9.53959654034165e-06 0.024470268782944 1 0.914353811833992 -4.91102501496396 8.3715451245151e-05 42.5441473634951 11.9761944034407 3.55239284954096 0.000450361431876412 -19.444942631019 27.7848787346478 -0.699839031752588 0.484630362793874 CYP4F2 other 0.626275290764974 1 1 3.55239284954096 -0.699839031752588 5.86676236215851e-15 65.7964708935213 13.480171812797 4.88098162302795 1.80124697466074e-06 -112.307608915031 25.7335657363157 -4.36424590613729 1.81352217394731e-05 ZBTB6 other 7.74647302299409e-11 0.277323810840022 0.0196137783070808 4.88098162302795 -4.36424590613729 0.00104659913844983 26.7160838560013 8.30554420298849 3.21665663357597 0.00145314960323204 -22.1817488615861 25.2792836315902 -0.877467462482468 0.381004319512391 C2orf76 other 1 1 1 3.21665663357597 -0.877467462482468 6.92443882962174e-20 180.148041885119 17.6858505328619 10.1859982108515 1.24689567467085e-20 -66.704546553217 59.8849100457973 -1.11387904736276 0.266392356902388 POLR3C essential 1.01076033595989e-15 1 1.91460830845709e-16 10.1859982108515 -1.11387904736276 3.18999339991194e-09 93.0589191406991 18.8623709939221 4.93357484966683 1.40544181194792e-06 -16.605284013999 31.612063536823 -0.525283140553494 0.59981272608932 WWOX other 3.34566507782764e-05 1 0.0154205075606925 4.93357484966683 -0.525283140553494 0.0665407232937435 6.51291287876158 5.68116487974744 1.14640448158426 0.252639046497441 -11.0645587510156 9.91778160890398 -1.11562839224874 0.265569518076512 CYP4Z1 other 1 1 1 1.14640448158426 -1.11562839224874 5.58140425029558e-22 61.2207180142118 6.27474326351335 9.75668891031776 1.77304858529523e-19 -26.3493927079341 17.4445672069482 -1.51046411156816 0.132085854297937 CIDECP other 8.35257146056734e-18 1 2.7067359703117e-15 9.75668891031776 -1.51046411156816 0.0331497285030548 27.4802646676356 23.6496251081637 1.16197464196376 0.246268093719689 -60.0329213610021 42.5057246671278 -1.4123490854734 0.158994508670138 CCDC84 essential 1 1 1 1.16197464196376 -1.4123490854734 3.20212515922302e-09 483.815982655662 147.925396111762 3.27067559305453 0.00121124334591447 -825.618564020637 265.165853744837 -3.11359306773756 0.00204549619284023 BCL9L other 3.35806865447718e-05 1 1 3.27067559305453 -3.11359306773756 3.01392817968183e-14 572.475244673582 129.080704292939 4.43501798204006 1.33940514065253e-05 -732.894346822156 201.501187158574 -3.63717135941931 0.00032989294607772 POLR1D other 3.90424256395984e-10 1 0.136137138495923 4.43501798204006 -3.63717135941931 7.10634356948004e-06 152.475365648889 39.9459674176509 3.81704025476961 0.000167150022142155 -128.424453920139 83.5590637680636 -1.53693026380249 0.125468551378222 KIF18B essential 0.0588760564731421 1 1 3.81704025476961 -1.53693026380249 1.02384847308418e-12 142.233843370211 49.3676663900062 2.88111336368544 0.00428082367232415 -357.93854482546 83.8365523183315 -4.26948073277572 2.71580433638577e-05 ZNRF1 other 1.26138131883971e-08 0.413291103911186 1 2.88111336368544 -4.26948073277572 0.208125010880615 -6.15549309706746 8.15800724389451 -0.754533909206106 0.451181452761764 -24.564854138775 13.8382996603819 -1.77513529419387 0.076993798140419 FFAR4 other 1 1 1 -0.754533909206106 -1.77513529419387 6.15583777250621e-10 378.410963219222 84.9525343436723 4.45438109813621 1.23325063040433e-05 -487.471671292055 159.931260426726 -3.04800743764159 0.00253212025953346 SAPCD2 other 6.73202418801279e-06 1 0.125742234276026 4.45438109813621 -3.04800743764159 0.114015303080341 -46.2948843480633 110.336875677294 -0.419577625919583 0.675124021793201 -641.457869708982 308.126919455574 -2.08179756199935 0.03829247798535 EDARADD other 1 1 1 -0.419577625919583 -2.08179756199935 0.0258999267808879 14.9066857146335 13.2528789252381 1.12478849303044 0.261673912855137 -51.7774385976899 30.32035521149 -1.7076791560169 0.0888411173290797 CYP4F12 other 1 1 1 1.12478849303044 -1.7076791560169 1.21809164399187e-06 176.448857740594 34.3831750448874 5.13183722882598 5.46664402315479e-07 201.059613962335 95.5217990364125 2.10485581291965 0.0362211436117936 MARC1 other 0.0107740205911081 1 0.00616582779371629 5.13183722882598 2.10485581291965 2.71843779747215e-05 38.3051494689919 20.76529801376 1.84467130900839 0.0661765624913978 -84.2320702766488 34.4016762241831 -2.44848738554887 0.0149799021593916 SOWAHB other 0.213941054661058 1 1 1.84467130900839 -2.44848738554887 1.27838351739364e-15 60.2566600368753 14.8252269311234 4.06446797184435 6.31241031019917e-05 -75.2724674922451 22.3551912927634 -3.36711354899529 0.000869673975887422 BLOC1S4 other 1.71725257891488e-11 1 0.604413287201571 4.06446797184435 -3.36711354899529 4.58418948308751e-07 26.3629420480277 6.32042361826529 4.17107201040163 4.0811563732163e-05 -22.7175801038477 14.0189934193794 -1.62048582407091 0.106286657103657 ZNF749 other 0.00419865914755985 1 0.397504630751268 4.17107201040163 -1.62048582407091 0.00334175824947904 10.8750392323903 3.45861000537574 3.14433810562252 0.00185191341934496 0.0577481290292392 6.35854743568237 0.00908196873788706 0.992760493754624 KLHL32 other 1 1 1 3.14433810562252 0.00908196873788706 5.22755688098464e-11 227.413945407366 54.2300168244923 4.19350682009483 3.7237819708267e-05 -316.37837839742 107.562990439245 -2.94133118747865 0.00355039503346801 MKL2 other 6.0242365496467e-07 1 0.364108467482386 4.19350682009483 -2.94133118747865 0.520497942011361 -0.32883399191858 2.27440947216881 -0.144579943032427 0.885149997260403 -9.62892289349353 8.44985779325221 -1.13953667968032 0.255485588197291 BTLA other 1 1 1 -0.144579943032427 -1.13953667968032 5.01388193740505e-18 28.4527242738532 4.56416719662058 6.23393557863529 1.72779983991667e-09 -41.619314969933 10.1235350284848 -4.11114446216938 5.21798741297222e-05 ZNF17 other 7.1076790344654e-14 0.78708122137273 2.21262047499729e-05 6.23393557863529 -4.11114446216938 2.17736010502567e-05 12.2325611492171 3.04632038381609 4.01552023687459 7.70672634546432e-05 -0.31461919244207 5.43404302423475 -0.0578978103483779 0.9538731721293 KDM4D other 0.173165449152692 1 0.731907801028746 4.01552023687459 -0.0578978103483779 0.388508283397372 27.6881605636809 35.5331705523861 0.779220095849892 0.436556023600201 -159.001031991744 158.698833104563 -1.00190422879154 0.317317813238248 GPAT2 other 1 1 1 0.779220095849892 -1.00190422879154 3.14071859378161e-09 569.764655424301 87.9274337115648 6.47994182672662 4.40244134736415e-10 65.2311299411445 273.335664667917 0.238648439896767 0.81156126452648 TOR3A other 3.29681230789255e-05 1 5.75927377062178e-06 6.47994182672662 0.238648439896767 0.248137526388635 -3.16998739226592 14.2767710171 -0.222038119716921 0.824450827983021 -40.7380250012683 26.7256555142199 -1.52430405232129 0.128594597034534 GABRA5 other 1 1 1 -0.222038119716921 -1.52430405232129 9.53105140114969e-05 491.423040630549 143.286351769129 3.42965700894079 0.000698121100520985 -483.71089587034 308.527280180102 -1.56780591845225 0.118089023808537 PPP1CC other 0.708157119105422 1 1 3.42965700894079 -1.56780591845225 9.89436002462596e-08 18.0743688205879 5.97856072089875 3.02319733199445 0.00274079982040412 -23.6708525186646 10.0518514003891 -2.35487489575783 0.0192423177419173 ZNF555 other 0.000948176521159906 1 1 3.02319733199445 -2.35487489575783 5.8091212222331e-07 41.5276158587623 9.61086672534563 4.3209022708895 2.18098242841937e-05 -15.5995890723693 16.0553194151613 -0.971614993697251 0.332105343703658 PRELID2 other 0.00527410115766543 1 0.217727475829105 4.3209022708895 -0.971614993697251 9.46919326765804e-05 162.415860684771 61.599764477847 2.63663119593875 0.00885296623886039 -178.049498140249 110.289474358898 -1.61438341396796 0.107599459959952 BACE1 other 0.703939827517699 1 1 2.63663119593875 -1.61438341396796 0.20605093708378 -920.979504979713 521.524718397268 -1.76593644076936 0.0785366187392285 -314.175235170737 983.104235649603 -0.31957469389107 0.749537890365723 THBS2 other 1 1 1 -1.76593644076936 -0.31957469389107 3.3119386874223e-07 763.153377313758 173.253142424984 4.40484580326842 1.52174945871936e-05 -492.880865864616 325.208407130096 -1.51558463759962 0.130781393322252 RXRA other 0.00306851119389676 1 0.15394017524405 4.40484580326842 -1.51558463759962 0.00286428935857521 64.2629497073409 33.2657856375873 1.93180315677648 0.0544262498325139 -51.5167132684636 51.1194319605221 -1.00777162994003 0.314463066453003 ANKRD37 other 1 1 1 1.93180315677648 -1.00777162994003 0.0541662954667109 29.8266491214081 15.7422450016794 1.89468840805274 0.059278454171677 -78.369720491728 53.3037935660945 -1.47024658563096 0.142742421918573 NUDT17 other 1 1 1 1.89468840805274 -1.47024658563096 0.0619828176446045 32.1921235458299 92.3052083693901 0.34875738990808 0.727541261453856 -290.777540518645 160.879627371725 -1.80742301103657 0.0718010851200489 CYP4X1 other 1 1 1 0.34875738990808 -1.80742301103657 0.241850997325858 -871.448192882638 991.708610105293 -0.878734120086053 0.380329694382472 2176.88199817728 2237.42445342567 0.972941005826723 0.331456686861702 KRT10 other 1 1 1 -0.878734120086053 0.972941005826723 0.041724894370221 -16.5038451631895 13.3256305815022 -1.23850387884076 0.216593171441124 55.7261711069622 30.1280348878773 1.84964506694012 0.0654454315621854 CD300E other 1 1 1 -1.23850387884076 1.84964506694012 1.19592383639979e-14 35.2380679218577 4.9476016212688 7.1222524809548 9.57053153870331e-12 -8.02614075076475 9.26462953716065 -0.866320743702888 0.387080636052316 CCDC30 other 1.56558389423096e-10 1 1.31757507693328e-07 7.1222524809548 -0.866320743702888 0.292174424176836 -14.8692289654234 19.3298086356223 -0.769238291269029 0.442421779900159 -59.0990465132112 37.6750905508527 -1.56865041726817 0.117896274831161 GLDN other 1 1 1 -0.769238291269029 -1.56865041726817 0.625727430093627 -2.0371981799462 2.52999397134693 -0.805218590644162 0.421394291184768 -4.79459768397047 5.90992255457118 -0.811279274761725 0.417912046734167 FCAR other 1 1 1 -0.805218590644162 -0.811279274761725 4.67709444736832e-15 542.69008264463 63.1389912240042 8.59516555656197 8.4914019189537e-16 -309.282329293259 408.833945735362 -0.756498653107093 0.450048618416037 KPNA4 other 6.19761785220775e-11 1 1.25401023539108e-11 8.59516555656197 -0.756498653107093 0.00706933414051768 27.610063866708 8.93717792039906 3.08934924565932 0.00221776333091482 6.76674456711257 16.1309876213214 0.419487307656756 0.675197344317322 TRDN other 1 1 1 3.08934924565932 0.419487307656756 0.933470971240965 -7.03977805356316 39.8904067954368 -0.176477970998492 0.860049299610771 -38.350073476133 104.609928170423 -0.366600705562629 0.714200849781853 KRT3 other 1 1 1 -0.176477970998492 -0.366600705562629 0.000795352830932086 20.5470824237418 6.22480803446769 3.30083792302824 0.00109275642293444 -11.9126792141131 16.3433319854951 -0.728901500910937 0.466689045919653 ZNF501 other 1 1 1 3.30083792302824 -0.728901500910937 1.12400546267831e-05 48.9484335359021 14.4356679647399 3.39079796345149 0.000800299937028186 -82.4194465750189 37.9010746474042 -2.17459392225079 0.0305224197413393 ZNF197 other 0.091606445208282 1 1 3.39079796345149 -2.17459392225079 3.22426386033271e-11 2473.73196448389 538.971143177822 4.58972988776087 6.78587982118732e-06 -2235.77530017154 845.115979231178 -2.64552482158186 0.00863110517729343 RPS23 essential 3.74820673763677e-07 1 0.0706545806982024 4.58972988776087 -2.64552482158186 0.175953419671359 -46.3368032493926 27.807469407878 -1.66634376432201 0.0968045964970245 -80.6892853680381 53.147022586331 -1.51822776594809 0.130127012021456 GNG2 other 1 1 1 -1.66634376432201 -1.51822776594809 0.724103895745703 39.3437601671208 90.2897014110335 0.435750252268671 0.663364825077893 -72.5099309042499 157.480562232224 -0.460437338274962 0.645571579210286 BTN3A2 other 1 1 1 0.435750252268671 -0.460437338274962 1.26869360483193e-05 126.822509980714 26.5331586565346 4.77977430514026 2.91745120169537e-06 71.6141293563932 86.9291093335181 0.823822191501279 0.410784213132045 PCLO other 0.102954486032111 1 0.0312838292357795 4.77977430514026 0.823822191501279 0.898490607392417 27.8467482244818 83.4366006290047 0.333747396401018 0.738828280476277 -31.2037021434143 185.382108638813 -0.168321001268842 0.866456305311231 KLK12 other 1 1 1 0.333747396401018 -0.168321001268842 0.089137474289107 -1.55643124619002 3.64711410427979 -0.426756937591724 0.669896451408154 -11.990094052077 5.76569121706693 -2.07955882489601 0.0385096134304898 RGS7BP other 1 1 1 -0.426756937591724 -2.07955882489601 1.45596834664835e-09 584.276912712404 101.223737332863 5.77213337609807 2.16703989217218e-08 -71.4295768760775 255.534833313965 -0.279529706184185 0.780054758676899 INSIG1 other 1.5600700834337e-05 1 0.000264487218839615 5.77213337609807 -0.279529706184185 9.08172902103043e-12 64.5194731027563 8.74656229684248 7.37655217136542 2.03664616602676e-12 -25.4651070983027 51.385828376033 -0.495566733145826 0.620606237339438 C5orf38 other 1.07836450395715e-07 1 2.84886065703823e-08 7.37655217136542 -0.495566733145826 9.39009314278185e-10 16.1344501637732 4.3146096406117 3.73949244722074 0.000226142354794368 -26.9812253075509 7.79886058754638 -3.45963682831258 0.000630524721541939 ZNF396 other 1.01582027618614e-05 1 1 3.73949244722074 -3.45963682831258 1.66092940504001e-22 112.986353602249 38.0631990062962 2.96838827402707 0.00326134129833231 -388.878733456461 55.292210850712 -7.03315580030661 1.64623310352336e-11 TMEM222 other 2.49704126753715e-18 2.62541255349906e-07 1 2.96838827402707 -7.03315580030661 0.549516115059989 23.3279361036936 47.3010403591642 0.493180190679972 0.622286147714803 161.494330675738 160.523861446425 1.00604563845256 0.315294367489654 ARHGAP30 other 1 1 1 0.493180190679972 1.00604563845256 7.69247168302349e-08 468.058407079648 80.1272183755204 5.84144085579094 1.47922474354693e-08 178.687610619468 260.771141539182 0.685227704126991 0.493785934391921 SEPT10 other 0.000742015818544446 1 0.000182225696157547 5.84144085579094 0.685227704126991 0.000421346745931814 982.637476999438 327.412088258427 3.00122540443235 0.00293955609861704 -758.120450382681 749.063722118992 -1.01209073139741 0.312397443112044 CYP4F3 other 1 1 1 3.00122540443235 -1.01209073139741 1.44205323720052e-23 152.554038011218 14.0533218771429 10.8553720853245 4.80204170709231e-23 -13.5739099869804 43.5843277831669 -0.311440159281817 0.755704596116693 SMYD4 other 2.18730635018574e-19 1 7.45757077111436e-19 10.8553720853245 -0.311440159281817 0.0463576050370753 4.00665189464216 3.92817882157245 1.01997696047816 0.308655828515027 -9.41007163923741 6.78989889005571 -1.38589274915701 0.166927474733633 FOXD2 other 1 1 1 1.01997696047816 -1.38589274915701 4.92313175740705e-09 181.402534945141 44.4482845100934 4.08120441417593 5.89336367751416e-05 -274.980199186543 91.9873747991637 -2.9893254350057 0.00305167723968381 GPATCH8 other 5.10824151148556e-05 1 0.56588078031491 4.08120441417593 -2.9893254350057 0.399086785780645 9.45621875340695 14.0265272896036 0.67416678114018 0.500779934877543 -35.695590044699 40.2311823762085 -0.887261769015477 0.375724723491682 CEACAM19 other 1 1 1 0.67416678114018 -0.887261769015477 5.12079719587102e-20 266.990088973613 35.6905115406067 7.48070222164921 1.03305484527853e-12 -376.642651158446 93.6197252181951 -4.0231121195947 7.45514110727314e-05 NF2 ts 7.4876296598026e-16 1 1.45505774957481e-08 7.48070222164921 -4.0231121195947 1.12113389689348e-11 959.978471939699 163.937327154351 5.85576505731277 1.37037077115176e-08 -920.454522703594 438.643698758364 -2.09841045319711 0.0367945721693304 UBE2H other 1.32775887409095e-07 1 0.000169055416810139 5.85576505731277 -2.09841045319711 2.89521243092597e-06 36.9312120313491 14.9531142007307 2.46980070743688 0.0141329188818389 -67.7572200804914 25.8779414527279 -2.61833887383452 0.00933117658524571 HPDL other 0.0248003896833119 1 1 2.46980070743688 -2.61833887383452 1.3881155881194e-20 46.6459472396027 5.12061520751833 9.10944200046802 1.82355375397502e-17 0.491692963799988 9.56808913071015 0.0513888360656914 0.959053260653379 KTN1-AS1 other 2.043861391947e-16 1 2.74262484597843e-13 9.10944200046802 0.0513888360656914 9.27231002440443e-25 183.062241311598 18.6445275845707 9.81855080431707 1.15230885871169e-19 -86.4975693149986 34.2413453116324 -2.52611480442078 0.0121032489563643 KATNA1 other 1.41727258723022e-20 1 1.76153455231256e-15 9.81855080431707 -2.52611480442078 7.52334460294524e-06 23.14392999047 5.61735497342161 4.12007610342858 5.04141925741147e-05 -12.6805901245776 10.9402562912728 -1.1590761483982 0.247449207899441 FSD2 other 0.062240629900166 1 0.486496958340207 4.12007610342858 -1.1590761483982 1.35275938693592e-09 613.746344311031 116.288092284556 5.27780903662258 2.73715603817816e-07 -529.302135755336 285.544868692257 -1.85365661858832 0.0649080190401255 ARAP1 other 1.45137554624354e-05 1 0.00315375118718888 5.27780903662258 -1.85365661858832 6.18892067166176e-33 106.33769630529 9.59115785036659 11.0870551777256 1.08622315485358e-23 -50.3470052792398 25.8553896197601 -1.9472537842076 0.0525685711058849 KIF24 other 9.75002562613593e-29 1 1.69038047358314e-19 11.0870551777256 -1.9472537842076 0.13067390850522 20.7452059342589 14.1680402641085 1.46422550667167 0.144326595683844 -26.9096238667976 34.7895568442373 -0.773497172938408 0.439922878729249 PDE2A other 1 1 1 1.46422550667167 -0.773497172938408 0.159476371181676 4.53669669801529 10.299625403317 0.440472009453299 0.659945124324774 -27.7715355017254 20.4996857509646 -1.35472981581772 0.176627816061162 CARMIL3 other 1 1 1 0.440472009453299 -1.35472981581772 0.93607517666417 -0.00020872328677791 1.83528347613449 -0.000113728091323269 0.999909341783439 1.64433888582164 4.84298864923046 0.339529783139781 0.734473642577583 PRG2 other 1 1 1 -0.000113728091323269 0.339529783139781 3.02672670471629e-09 125.306876753551 24.6508658277268 5.08326472705913 6.91091421898003e-07 -99.9438129902018 56.5059127532998 -1.76873194539036 0.0780593500589428 PRR5 other 3.18199778466824e-05 1 0.00774575265663282 5.08326472705913 -1.76873194539036 7.08669348357419e-09 235.362423096136 54.783431641458 4.29623366123752 2.41807799846686e-05 -349.475133099804 131.445592572601 -2.65870560024126 0.00830726071545513 ZFP91 other 7.28441223176591e-05 1 0.240574580067468 4.29623366123752 -2.65870560024126 2.24903564920373e-07 74.3008664845202 13.6516606233336 5.44262478643251 1.18215668695944e-07 -9.23397820867638 30.6856980669969 -0.300921236613734 0.763707015244729 C17orf58 other 0.00210509736765469 1 0.00139222593023214 5.44262478643251 -0.300921236613734 1.17729937211347e-05 23.8061363464401 8.02694499046912 2.96577793602753 0.0032862429538841 -53.2662244003632 20.4911691730111 -2.59947218973332 0.00984464388769422 BCDIN3D other 0.0958557148774786 1 1 2.96577793602753 -2.59947218973332 0.191097412257174 -21.9247278229123 18.689340737886 -1.1731140295638 0.241780147598796 -86.762546459231 50.8521057186964 -1.70617411477873 0.0891213138529729 CYP27C1 other 1 1 1 -1.1731140295638 -1.70617411477873 1.97498114486084e-10 119.805164877964 23.2104300404234 5.16169518054215 4.72900447808089e-07 -58.5404856182565 37.949960958171 -1.54257037794533 0.124097636675762 LYRM7 other 2.21553384830489e-06 1 0.00535559757142661 5.16169518054215 -1.54257037794533 2.64459819513382e-05 74.2657688419514 19.2187001553092 3.86424514882893 0.000139503697250734 -60.5672669491524 40.5983296372657 -1.49186598291859 0.136897433220162 CFAP73 other 0.208447229740448 1 1 3.86424514882893 -1.49186598291859 2.4776274104588e-20 168.876392066166 20.2806034282046 8.32699049927216 4.47546161681564e-15 -81.195905031549 45.4053891339745 -1.78824378736123 0.0748790499532986 CCDC73 other 3.63690927581247e-16 1 6.55476108398818e-11 8.32699049927216 -1.78824378736123 1.5862161878192e-09 247.087073602533 81.144696696425 3.04501814242925 0.00255483484550905 -1303.8289650945 275.373266990549 -4.7347695705671 3.53327288523892e-06 BCR other 1.69550648315995e-05 0.0548434617246785 1 3.04501814242925 -4.7347695705671 0.00724726340870843 50.3843291971724 27.8654820012581 1.80812695775001 0.0716911672125422 -110.833224425364 63.4836529050792 -1.74585455236929 0.0819652907285615 MPPED1 other 1 1 1 1.80812695775001 -1.74585455236929 3.29421640142843e-06 44.9380403458211 11.1819421605098 4.01880457802085 7.57790543414708e-05 -45.388040345822 26.5242330616052 -1.71119143163927 0.0881857997307752 HYAL3 other 0.0280766063893745 1 0.720355690570022 4.01880457802085 -1.71119143163927 0.0960948571764599 75.0842010645065 35.1930369027502 2.13349593193644 0.0337822311018202 93.2399621766836 77.2634009702635 1.2067804549863 0.228569046291707 VSIG10L other 1 1 1 2.13349593193644 1.2067804549863 8.96450966584124e-20 247.849077586491 34.0725804730656 7.2741504795158 3.97374464459536e-12 -208.836767220543 61.5877975300961 -3.39087896621877 0.000803343497630244 ZNF397 other 1.30612905831307e-15 1 5.52271030705863e-08 7.2741504795158 -3.39087896621877 8.81254695036481e-12 93.2804633364103 20.6601760629173 4.51498879062498 9.54956277036591e-06 -130.74570040682 37.3442434542031 -3.50109383169482 0.000543834444118137 ZSCAN30 other 1.04763558145937e-07 1 0.0982172530932134 4.51498879062498 -3.50109383169482 0.245768238932733 66.5938010840573 52.2038666760456 1.27564882305193 0.20317203974316 -77.6483050847456 110.277478212723 -0.704117525565496 0.481964176511132 TPCN1 other 1 1 1 1.27564882305193 -0.704117525565496 0.361305912909219 -35.4071375014798 52.6548792009879 -0.672437921020156 0.501873678616419 -175.053741729258 123.051748676502 -1.42260263354296 0.155992995767193 LILRB4 other 1 1 1 -0.672437921020156 -1.42260263354296 0.0519127202563906 78.9807202183811 40.2638847360692 1.96157724809967 0.0508746082909497 -7.21833492893131 63.3000162830343 -0.114033697821749 0.909298750302437 TNFRSF4 other 1 1 1 1.96157724809967 -0.114033697821749 0.174667486731675 -2008.15101875523 3118.49059972914 -0.643949678389169 0.520150676249877 -11136.4409655303 5974.92771142598 -1.86386204208527 0.0634184343407418 KRT16 other 1 1 1 -0.643949678389169 -1.86386204208527 0.0766171265645002 140.128673250272 61.5312247158694 2.27735875398774 0.0235384008011667 109.524872346221 129.275075012508 0.847223429076521 0.397612706485879 HEXIM1 other 1 1 1 2.27735875398774 0.847223429076521 0.653192041325238 230.15438682709 6129.31521376711 0.0375497716792469 0.97007419981941 -9539.88745479694 11743.5708563569 -0.812349801562524 0.417301337733742 KRT14 other 1 1 1 0.0375497716792469 -0.812349801562524 5.2066105433624e-05 22.597146855056 9.48973168517419 2.38122084003276 0.0179437656341074 -23.768602891824 13.5452565295381 -1.75475472465153 0.0804271939811572 PDZD7 other 0.398201574356357 1 1 2.38122084003276 -1.75475472465153 4.69535034252191e-09 129.664981891643 45.3937078321123 2.85645275709149 0.0046146009499012 -229.23604055037 67.8558953135469 -3.37827744356068 0.000836088449892402 POFUT2 other 4.87565179567475e-05 1 1 2.85645275709149 -3.37827744356068 0.428409044530668 8.24842918845192 22.2966988077556 0.369939481156862 0.711718668201777 40.233232552853 32.7523941518718 1.22840584924243 0.220368301120408 QRFPR other 1 1 1 0.369939481156862 1.22840584924243 0.360657098144315 4.46239587150762 49.2033184290094 0.0906929860421096 0.927804290320593 -132.468301754567 101.505506345003 -1.30503562343038 0.19300010459905 MAPT other 1 1 1 0.0906929860421096 -1.30503562343038 4.27417889419431e-08 38.0079888782284 6.45369070800438 5.88934155631101 1.18957660163807e-08 -46.2284911736066 39.9435299974298 -1.15734616285995 0.248189025443738 TMEM17 other 0.000418955015208926 1 0.00014724579175076 5.88934155631101 -1.15734616285995 0.828360635714427 28.8368625155243 50.2057488816937 0.574373715318465 0.566209632997321 39.5429674023663 78.9299080936968 0.50098838776583 0.616801536655331 TNFRSF18 other 1 1 1 0.574373715318465 0.50098838776583 0.892834788090452 -10.0263275238844 26.0190402897679 -0.38534578571014 0.700331297705385 12.5256444313732 85.7061718146321 0.146146352895845 0.883931676663731 FGF3 other 1 1 1 -0.38534578571014 0.146146352895845 0.651012737317329 4.56180170697374 7.47014008123934 0.610671507811525 0.54192700080418 -8.48501959342064 19.0557426205823 -0.445273624983571 0.656476188218375 C1QL4 other 1 1 1 0.610671507811525 -0.445273624983571 0.0932805363770404 51.5472347855117 27.8222644212282 1.85273326444922 0.0650077150461685 -30.9579736160016 72.3222031166146 -0.428056285371783 0.668950126782637 RTN4RL2 other 1 1 1 1.85273326444922 -0.428056285371783 1.15554603681098e-07 90.6774651752132 23.7104720556244 3.82436355389658 0.000163007642043795 -171.06519458299 56.2132376248655 -3.04314787425303 0.00257285391473081 ZDHHC17 other 0.001102275364514 1 1 3.82436355389658 -3.04314787425303 0.238961344983726 -3.58920146554157 6.42157193862564 -0.558928794981271 0.576670186807949 15.6897318019833 13.1983946023626 1.18876062390002 0.235570684977627 SERPINA11 other 1 1 1 -0.558928794981271 1.18876062390002 3.06507133851922e-12 681.509936524499 147.233018019934 4.62878466861441 5.71877225838324e-06 -487.870285752204 250.492964475468 -1.94764067235902 0.0524943551356088 ZNF395 other 3.70597775540359e-08 1 0.0598755455452725 4.62878466861441 -1.94764067235902 6.51586155481023e-09 352.971928885646 58.8673587534258 5.99605513751888 6.43609059590975e-09 -81.2629168257585 134.560207613039 -0.603914918587597 0.546405401458224 ZACN other 6.71589850454291e-05 1 8.05541098984064e-05 5.99605513751888 -0.603914918587597 2.28548333573838e-12 163.254876476102 32.811041697092 4.97560784516547 1.15959932256721e-06 -249.399363907093 72.7310350872482 -3.429063859849 0.000700311847352952 PPARA other 2.77891918792429e-08 1 0.0127961785245292 4.97560784516547 -3.429063859849 3.80932678478101e-05 -4.25455321191442 7.64702796253123 -0.55636689610144 0.578415809281764 -54.586237700328 12.7080590895558 -4.29540320167301 2.42657057567177e-05 TMEM232 other 0.295260919088376 0.369712292909351 1 -0.55636689610144 -4.29540320167301 0.034744242252695 12.8798218398015 9.44542161794968 1.36360475590896 0.173827818196707 -23.1612302878026 17.6727160589049 -1.31056427379945 0.191118717001313 FAM183A other 1 1 1 1.36360475590896 -1.31056427379945 0.000610865974146226 8.37949730728246 3.60256961079692 2.32597790259737 0.0207549955277746 -16.6300637723753 8.19568686908657 -2.02912385966117 0.0434194443701459 EFCAB6 other 1 1 1 2.32597790259737 -2.02912385966117 0.210003117152731 1.44365980534736 18.3398219149261 0.0787172204857897 0.937315214538532 67.3340418391319 42.1579771318245 1.59718388832045 0.111381538486687 KANK3 other 1 1 1 0.0787172204857897 1.59718388832045 0.716292744048518 7.48272484319456 70.3949764062085 0.106296290235486 0.915426207557273 -133.762457283426 184.643371398682 -0.72443682256324 0.469424875196077 EMID1 other 1 1 1 0.106296290235486 -0.72443682256324 5.85369107688663e-05 91.067118529154 74.5684346223087 1.22125560219162 0.223062513151704 -342.706821389399 117.232278980221 -2.9233145032284 0.00375901279711194 ESPN other 0.445407354040304 1 1 1.22125560219162 -2.9233145032284 4.82949765073909e-05 26.745692398745 9.03575254221075 2.95998504538519 0.00334769638907798 -32.0064748951246 16.7455340208878 -1.91134393535619 0.057011290249541 PTRH1 other 0.370325879858673 1 1 2.95998504538519 -1.91134393535619 0.12717830210656 -2.72671824656636 2.14826767493117 -1.26926373206901 0.205428019271051 -10.7755282817424 5.56582858999518 -1.93601511572094 0.0538980645973238 GPR141 other 1 1 1 -1.26926373206901 -1.93601511572094 0.121107130581371 -7.62976793273278 13.24554634598 -0.576025158452481 0.56507272818127 50.6945405624312 31.2110470696001 1.62424991540282 0.1054764635878 TMPRSS6 other 1 1 1 -0.576025158452481 1.62424991540282 1.20670248957653e-07 95.765587616384 22.9490075796176 4.17297293942415 4.05786721722744e-05 -109.107092411783 48.1172256386485 -2.26752666978676 0.0241486522491659 TMEM216 other 0.00114974613206852 1 0.395398581646642 4.17297293942415 -2.26752666978676 7.55840588265789e-09 262.552652625965 50.6090255344146 5.1878622410429 4.16267855136812e-07 -210.880879913504 125.880777999332 -1.67524290257106 0.0950357741613428 RPS19BP1 essential 7.75870363854833e-05 1 0.00473629565574665 5.1878622410429 -1.67524290257106 0.00457752602621192 301.264826560873 175.792649556944 1.71375098629072 0.0877221875797414 -501.802013622556 334.902630880634 -1.49835196069692 0.135210043172328 TMPRSS11A other 1 1 1 1.71375098629072 -1.49835196069692 6.00389841586343e-08 117.135670962213 27.9967472782894 4.18390285835271 3.87470100117989e-05 -179.693795258657 64.7574738786263 -2.77487345469117 0.00590653016119593 TMEM262 other 0.000583038575164497 1 0.378093323695133 4.18390285835271 -2.77487345469117 0.00175590140898579 21.7233198913692 6.16764223028484 3.52214332159243 0.000502731714346185 -33.5959312715021 65.4615984613569 -0.513215871001597 0.608221553333453 C3orf70 other 1 1 1 3.52214332159243 -0.513215871001597 4.16248710899985e-06 225.055917112802 99.7543660050983 2.25610092195163 0.0248766666426134 -377.73235785028 156.820252076665 -2.40869628028412 0.0166899148511467 TEAD1 other 0.0352271284034657 1 1 2.25610092195163 -2.40869628028412 0.0678936083365243 181.584837545125 78.2277141568498 2.32123409845569 0.0210135048411751 144.612876052948 244.189806069472 0.592215041162716 0.554198555416078 PLCD1 other 1 1 1 2.32123409845569 0.592215041162716 3.22335438313304e-24 279.134353359258 29.0012166401401 9.62491873437174 4.53500178660585e-19 -70.4310443533171 56.6698834992535 -1.24283023017411 0.21499678781848 ENTPD5 other 4.91303675077138e-20 1 6.90544722046473e-15 9.62491873437174 -1.24283023017411 0.617156417009563 -25.3547310624231 28.6365738376648 -0.885396807807884 0.376724701691906 -45.1834070757145 59.8017992188027 -0.755552636642212 0.450571241460413 MITF og 1 1 1 -0.885396807807884 -0.755552636642212 1.22498842535917e-13 15.1338222605694 2.02360652032217 7.47863881075063 1.03766445565847e-12 2.25918895599652 3.96459800655351 0.569840612405612 0.569256147014571 HEATR4 other 1.55745028400165e-09 1 1.46144661934939e-08 7.47863881075063 0.569840612405612 1.38443462367927e-09 2010.53976401465 331.140334895525 6.07156408369575 4.29794916758622e-09 -577.992187626104 785.073797307385 -0.736226568264638 0.462234350385714 NAP1L1 other 1.48480613389601e-05 1 5.41842451557595e-05 6.07156408369575 -0.736226568264638 0.469265131640432 16.952478300919 13.9650675145236 1.21392025375377 0.225827286620879 8.76834537791901 35.7003813760222 0.245609291552503 0.806169236853592 LILRA5 other 1 1 1 1.21392025375377 0.245609291552503 1.1792386657336e-06 141.401470475606 36.5223339204626 3.87164387641672 0.000135661506355081 -206.016053543015 96.0165618412054 -2.14563039534502 0.032794260599296 CMC1 other 0.010446875339734 1 1 3.87164387641672 -2.14563039534502 0.499848718853681 1.72030240430803 10.2951246403264 0.167098744736857 0.867416057713174 -14.9771634030587 16.1511011046784 -0.927315314664234 0.35458193708702 SLIT1 other 1 1 1 0.167098744736857 -0.927315314664234 0.279222591270924 22.1150712830956 17.1115527367261 1.2924058747533 0.197325692903738 -16.5990042996153 39.9549874555972 -0.415442610714424 0.678149106724178 LYPD6 other 1 1 1 1.2924058747533 -0.415442610714424 0.0502099700593739 10071.5912791812 4235.30076385846 2.3780108759043 0.0181158094339037 6255.93828600629 7273.77587479456 0.860067507398004 0.390529243743534 AKR1C1 other 1 1 1 2.3780108759043 0.860067507398004 0.140964244828216 2.88738827562329 2.32443107991731 1.24219139064601 0.215231975655554 -7.58997964898797 7.1791027241686 -1.05723235069978 0.291340177640734 FOXD3 other 1 1 1 1.24219139064601 -1.05723235069978 7.72838952475357e-27 193.999028819522 35.1876522005592 5.51327004466751 8.16017469376622e-08 -337.981536289056 53.9246646415792 -6.26766134820711 1.42400995448659e-09 SPATA21 other 1.19535000779363e-22 2.26716624853809e-05 0.000968775939643926 5.51327004466751 -6.26766134820711 7.72880499759167e-21 272.797223317471 47.0996203371334 5.7919197939351 1.91795542133857e-08 -390.22480231174 82.5986521557465 -4.72434830505393 3.7048423307351e-06 RNF220 other 1.1421628025441e-16 0.0574806287613551 0.000234776923126054 5.7919197939351 -4.72434830505393 9.30785957784292e-06 118.66229306905 49.8292543025915 2.38137806254264 0.0179337312244736 -153.567274881192 70.2360263517016 -2.1864459431719 0.0296320554624902 SHTN1 other 0.0764826821511353 1 1 2.38137806254264 -2.1864459431719 1.10749804480778e-39 30.3765972110251 1.93746776453916 15.6785045754041 6.5745601854986e-40 2.95565962896593 12.4432922534206 0.237530355212339 0.812424188957674 ZNF546 other 1.75671339867411e-35 1 1.04456612227202e-35 15.6785045754041 0.237530355212339 4.31552620972622e-07 206.082737023154 45.0288134384784 4.57668593254671 7.17997236215112e-06 -100.959756499916 81.7082271119955 -1.23561310859839 0.217664608558142 TSPYL4 other 0.00396208461314964 1 0.0746573526216474 4.57668593254671 -1.23561310859839 0.00126044122794688 600.258973164231 249.493329185711 2.40591191405132 0.0167996897224552 -373.640549237741 448.177776027808 -0.833688257702805 0.405188187520699 MT1X other 1 1 1 2.40591191405132 -0.833688257702805 0.650297829878622 17.7490790314488 36.8734600834928 0.481351058220721 0.630655450817796 64.0946704116415 69.1603974951888 0.926753933363387 0.354878907917709 GCNT1 other 1 1 1 0.481351058220721 0.926753933363387 0.0147616247646872 120.928079797976 46.2428356738532 2.61506626995955 0.0094263124009217 -46.87849717471 124.163493914477 -0.377554591102273 0.706060328263633 SESTD1 other 1 1 1 2.61506626995955 -0.377554591102273 0.00508823205146634 149.625170245039 65.6680683539761 2.27850725619798 0.0234718506582547 -153.263531054001 125.622280811779 -1.22003461538513 0.223508493286978 FNBP1 other 1 1 1 2.27850725619798 -1.22003461538513 0.0317811668482138 41.6673314138506 26.3704989264051 1.58007368499686 0.115282826980355 -83.5151981705217 57.8548334929437 -1.44353017938782 0.15005227651538 DYNC2H1 other 1 1 1 1.58007368499686 -1.44353017938782 1.17583902929221e-06 1945.93615471918 406.28109736507 4.7896300550026 2.75391576048475e-06 -735.858257178661 1162.28923518331 -0.633111135252494 0.527194963061768 BCAM other 0.0104191096385583 1 0.0295825630991272 4.7896300550026 -0.633111135252494 4.36316357462139e-15 183.659705266436 25.3159359845197 7.25470728709145 4.2384690048812e-12 -162.301410500291 78.9040735907635 -2.05694589790216 0.0406485016399551 RSBN1L other 5.78599121630543e-11 1 5.88680960087949e-08 7.25470728709145 -2.05694589790216 0.735108054080648 3.54753259113713 7.61422233583631 0.465908721162591 0.641653702869453 -8.92767844030986 20.1218178756145 -0.443681505095483 0.657625597923409 NPSR1 other 1 1 1 0.465908721162591 -0.443681505095483 0.000704839848506205 20.831831031662 9.49935859800225 2.19297237984499 0.0291562136082805 -47.8666646617265 24.1965767789466 -1.97824118258642 0.0489104118779265 WDR86 other 1 1 1 2.19297237984499 -1.97824118258642 0.000677167788453493 20.4567188451554 11.5663023364799 1.76864811674819 0.0780733792542488 87.4904006777196 22.604486150795 3.8704883665158 0.000136052678749473 EPOR other 1 1 1 1.76864811674819 3.8704883665158 0.0244994061232048 137.99604362532 60.0486237236797 2.29807171368862 0.0223280258274732 -2.25216194150525 101.064081978943 -0.022284494128928 0.982237600288988 DCC ts 1 1 1 2.29807171368862 -0.022284494128928 0.390959274161296 17.2616178148093 15.8212270035394 1.09104166263133 0.276216544509004 -6.36187295761777 27.6008610588059 -0.230495452444881 0.817879426961809 PCDHB13 other 1 1 1 1.09104166263133 -0.230495452444881 0.0243349534239846 26.0974849027803 12.4327662657975 2.09908916043684 0.0367410836333066 -37.4126625366455 38.4492494913346 -0.973040125141513 0.33140751494328 MAGI2 other 1 1 1 2.09908916043684 -0.973040125141513 0.243136562558356 11.8651763186451 8.73777055347767 1.35791804625983 0.17562759931496 -3.65837721604945 16.8756831082056 -0.216783948394398 0.828541039765926 LUZP2 other 1 1 1 1.35791804625983 -0.216783948394398 3.38910598539273e-08 296.638234770745 128.52774262758 2.30797047163802 0.0217513218722595 -815.827837422808 224.758901041913 -3.62979100556588 0.000338800166832104 CHP1 other 0.000334165850159723 1 1 2.30797047163802 -3.62979100556588 0.831280526157805 9.13374008214226 46.377744869756 0.196942307302626 0.844019225104452 -49.1717477397721 107.300005333992 -0.458264168643007 0.647127233165477 FPR3 other 1 1 1 0.196942307302626 -0.458264168643007 0.191335580619458 -93.3233469881314 89.0528251927326 -1.04795492772022 0.295617826115926 -331.646795877745 183.710259601267 -1.80527095545761 0.0721714970455931 C11orf96 other 1 1 1 -1.04795492772022 -1.80527095545761 1.82723224331085e-05 69.771108580059 18.0032983792101 3.87546254638702 0.000133446181952956 -6.27318800347623 33.9734088023236 -0.184649943135738 0.853641208394322 KCNJ11 other 0.146379575011632 1 1 3.87546254638702 -0.184649943135738 0.871983046825117 -4.61282252876856 16.7601099240144 -0.275226269379007 0.7833513601847 -20.3498963619472 39.8554983884988 -0.510591943013304 0.610050948957704 CDHR4 other 1 1 1 -0.275226269379007 -0.510591943013304 0.0259485564386069 1361.84075964844 610.050290909094 2.23234179204968 0.0264314130861127 -573.771094616812 1196.95075077823 -0.479360653931465 0.632078923643416 COL4A1 other 1 1 1 2.23234179204968 -0.479360653931465 0.170327258704314 -13.195631865021 11.5068972141773 -1.14675847184618 0.252489215546456 -46.2418280300456 26.3716429753005 -1.7534678470111 0.0806481188793029 PLEKHG7 other 1 1 1 -1.14675847184618 -1.7534678470111 0.56393712625294 -21.3740938471825 25.6822228068416 -0.832252488732735 0.405999228063181 -37.2995720281666 36.9006359730608 -1.01081108887655 0.313008496796631 GJA4 other 1 1 1 -0.832252488732735 -1.01081108887655 7.48728102258962e-16 237.752922120687 36.6065346845953 6.49482187181015 3.93711112550502e-10 -84.1378708368253 61.6781990514177 -1.36414279487448 0.17365030449956 HSPA14 essential 1.01145679334163e-11 1 5.16037155219943e-06 6.49482187181015 -1.36414279487448 0.594407634139354 -3.41296914513885 24.178129301731 -0.141159355322601 0.88785009929125 189.214361375625 191.006813093239 0.990615770774943 0.322766768135744 ATP13A5 other 1 1 1 -0.141159355322601 0.990615770774943 2.20003689118863e-07 185.148699433771 34.5337955058516 5.36137707198732 1.78844257631287e-07 10.9243185041344 76.7957670238944 0.142251570984835 0.886988579722901 SIRT7 other 0.00206077455597639 1 0.0020829990686316 5.36137707198732 0.142251570984835 0.000427091897283368 98.9761492919588 42.6350019992528 2.32147636098841 0.021000234923881 -109.029634673445 77.9594887472514 -1.3985421970496 0.163089434252006 IFT140 other 1 1 1 2.32147636098841 -1.3985421970496 0.604335288537895 0.870607202605872 1.34208370113708 0.648698141455894 0.517095252160359 -1.50225056575994 3.48568894202125 -0.430976656479517 0.666835696031844 POTEG other 1 1 1 0.648698141455894 -0.430976656479517 0.389475888459877 8.86603979803273 6.44556904662884 1.3755247572237 0.170100523903532 5.10351324836106 16.8063158858321 0.303666388459554 0.761614221636845 AGMO other 1 1 1 1.3755247572237 0.303666388459554 0.0699136425885515 -9.48394442005619 21.2003235182835 -0.4473490421916 0.654979095406077 -136.693358845647 59.347986004055 -2.3032518548533 0.0220192194059588 TLR5 other 1 1 1 -0.4473490421916 -2.3032518548533 5.60987810059147e-20 803.882559915022 110.457926423606 7.27772633384528 3.79368115427296e-12 -564.484442747868 212.542717924383 -2.65586348128236 0.00838636752755242 USP7 essential 8.19827585620438e-16 1 5.27549301313198e-08 7.27772633384528 -2.65586348128236 2.86551084670157e-05 30.562670164802 6.64977457597645 4.596046048721 6.60780991932385e-06 9.35487047612022 12.49641524453 0.748604323165004 0.454744942596672 NHLRC1 other 0.224885291249139 1 0.0688798105990318 4.596046048721 0.748604323165004 0.00446968550567701 -6.80591009497202 23.4153347591091 -0.290660379831826 0.771542787071257 -107.194875111306 36.9087686614373 -2.90432000304861 0.00399688388526988 PLEKHN1 other 1 1 1 -0.290660379831826 -2.90432000304861 0.123466594173642 11.4650864519604 8.19907717624474 1.39833864293634 0.163154660898377 -11.1752950884249 15.2582570311734 -0.732409675993345 0.464551517095605 ZNF385C other 1 1 1 1.39833864293634 -0.732409675993345 0.00298476360770325 276.874986808184 80.4454793171763 3.44177185788819 0.000669197750809949 129.501301951528 352.998439507363 0.366860834093932 0.714009113744523 TET3 other 1 1 1 3.44177185788819 0.366860834093932 3.96381203186117e-14 120.214222309893 16.2870561554886 7.38096689556644 1.90140070167198e-12 -27.3459040548492 42.427339020782 -0.644534978765803 0.51976978251964 ZNF286A other 5.11807409553915e-10 1 2.66196098234077e-08 7.38096689556644 -0.644534978765803 0.241774969205277 -30.2507409021071 287.991960501787 -0.105040226988973 0.916424876725247 -660.515286712078 453.951598636836 -1.4550346087458 0.146865929896258 ISG15 other 1 1 1 -0.105040226988973 -1.4550346087458 0.000629737623888758 27.1390816899017 15.1428636098357 1.79220274243731 0.0742283950884478 -71.525135898391 28.5058779047531 -2.50913640117938 0.0126931791822972 EXD3 other 1 1 1 1.79220274243731 -2.50913640117938 0.908097201000738 -2.14667931204682 11.7682544052106 -0.182412721388512 0.855395727742013 -11.5241584605584 26.2404366687614 -0.439175559691719 0.660885593927348 TCL6 other 1 1 1 -0.182412721388512 -0.439175559691719 0.0535799030151782 18.6071666191424 8.30312993610568 2.24098222746464 0.0258494368717828 -7.46719871944555 25.0119027058279 -0.298545808660356 0.765518831877062 C17orf97 other 1 1 1 2.24098222746464 -0.298545808660356 6.10391186801243e-15 36.7099637098763 4.99334350440319 7.35178016042858 2.30050203039875e-12 -13.3820750414563 9.0462986116197 -1.4792873434741 0.140220724592287 ZKSCAN4 other 8.05655327458961e-11 1 3.21495158748225e-08 7.35178016042858 -1.4792873434741 0.202508442025468 21.3941824562203 12.8536840576114 1.6644397326346 0.0972020505749227 -20.5070924814 51.8148569438293 -0.39577630222218 0.692587308883727 RGPD1 other 1 1 1 1.6644397326346 -0.39577630222218 1.45540994348285e-10 129.25754952525 28.1104978150395 4.59819496530209 6.53510585622858e-06 -114.977465935254 55.9075203630443 -2.0565652919076 0.0406818856597023 DHRS4L2 other 1.64199349823735e-06 1 0.0681611540804641 4.59819496530209 -2.0565652919076 1.25208486546479e-09 87.0438016383079 33.333916075281 2.61126839828027 0.00954683453135865 -190.572845377631 52.5178045299689 -3.62872833476658 0.000343079462503231 SAMD11 other 1.3458660218881e-05 1 1 2.61126839828027 -3.62872833476658 0.0164940997707976 -3.89193598605819 8.96435436541291 -0.434156864779288 0.664534593486534 -36.8402792280768 14.1301965090829 -2.6072021860698 0.00965589980715482 PERM1 other 1 1 1 -0.434156864779288 -2.6072021860698 4.40984814184341e-12 17.5470394032742 6.5335450160067 2.68568431996492 0.00768316468380174 -57.0871569873977 12.3026607630794 -4.6402284909552 5.41628839257089e-06 VMAC other 5.29490466391138e-08 0.0837574837027163 1 2.68568431996492 -4.6402284909552 0.0991290944805313 12.7083133273887 5.96617231850326 2.1300613943006 0.0340674371145944 17.424120310035 13.740502490467 1.26808465135272 0.205856062515998 HAPLN4 other 1 1 1 2.1300613943006 1.26808465135272 0.706381559939289 8.13045873003379 10.0131436284118 0.811978638453167 0.417513916797066 1.70375324573128 25.2246845511485 0.0675430942367804 0.946198978416776 ERC2 other 1 1 1 0.811978638453167 0.0675430942367804 4.15912250438315e-09 88.0728710093329 22.0295764392709 3.99793755690783 8.25941509985646e-05 -73.9904568814734 33.6524679115107 -2.19866361884756 0.0287534444685951 B3GLCT other 4.33172608831505e-05 1 0.781588450899417 3.99793755690783 -2.19866361884756 0.0367951759737202 315.711006023733 131.805891287776 2.39527234283049 0.01728204640046 51.18811156654 218.892525781883 0.233850431318732 0.815276361604857 SPRY4 other 1 1 1 2.39527234283049 0.233850431318732 0.0912532888985473 -111.353878546811 52.4508342689794 -2.12301444007093 0.0346524451769988 -184.936120198326 135.198493305677 -1.3678859555054 0.172472673440396 TRPV2 other 1 1 1 -2.12301444007093 -1.3678859555054 0.18713183030481 -195.914534376177 206.760278394981 -0.947544353765643 0.344208741320484 -780.314818260887 424.891559626462 -1.83650345736896 0.067382523983101 AMTN other 1 1 1 -0.947544353765643 -1.83650345736896 0.785675882879762 -0.374411356167661 11.479237301395 -0.0326163965721103 0.974004681747501 -19.6347004961701 29.0915515429596 -0.674927924252355 0.500301241068804 C2orf88 other 1 1 1 -0.0326163965721103 -0.674927924252355 8.50677074547776e-29 246.406013056007 28.265483809968 8.71755865608463 2.98808062712579e-16 -292.352631882479 53.2663039113 -5.48850981606139 9.36642530006e-08 TMEM203 other 1.32612049151253e-24 0.00148045718292748 4.44058661997164e-12 8.71755865608463 -5.48850981606139 0.223023007800267 8.54108046158713 13.8499626596113 0.616686172482927 0.53795945602441 36.3772921277269 21.6894137294729 1.67719112104423 0.0946581052599769 SLC18A3 other 1 1 1 0.616686172482927 1.67719112104423 0.596350159870169 -2.93675607442276 4.74041057338893 -0.619515130378941 0.53609755081343 -16.3631038108631 17.9745130578686 -0.910350325384747 0.363446766599233 KBTBD12 other 1 1 1 -0.619515130378941 -0.910350325384747 0.167920962960295 4.31243855854863 89.1610618007169 0.0483668371759336 0.961459778930749 -289.272294469567 167.21456506491 -1.72994675647588 0.0847867823177022 THSD4 other 1 1 1 0.0483668371759336 -1.72994675647588 0.529569659855884 1.87419932304227 4.80418712352703 0.390117885680171 0.696755825032677 -11.4615212328275 13.2115861400108 -0.86753559424002 0.386416148849346 DNAJB13 other 1 1 1 0.390117885680171 -0.86753559424002 0.0190327663222548 -8.66296022897228 7.21382940948259 -1.20088232438444 0.230853202360607 -32.4281283129947 11.521116657951 -2.8146688620339 0.00524352111561464 GABRD other 1 1 1 -1.20088232438444 -2.8146688620339 0.817820696668561 -7.51558752997618 22.3519695353053 -0.336238268314799 0.736953329522213 -19.9690947242207 31.5994316863467 -0.631944742628041 0.527959683861121 AMY1C other 1 1 1 -0.336238268314799 -0.631944742628041 8.02467921911053e-15 490.750097871651 60.8654417291441 8.06286923958471 3.09597198021687e-14 -8.81601180188794 195.698030252191 -0.0450490574203888 0.964104168712154 TCEA1 other 1.05492433014427e-10 1 4.4767754833936e-10 8.06286923958471 -0.0450490574203888 4.26862655823598e-15 45.6235650445951 11.3243252521264 4.0288109029744 7.2935550062604e-05 -71.5813789832316 16.8018607555132 -4.26032449767466 2.82214511803718e-05 NHEJ1 other 5.6619062668442e-11 0.429276493904635 0.69434643659599 4.0288109029744 -4.26032449767466 9.09726084594137e-09 291.689771849152 68.7136518602513 4.24500465267638 3.03727840687023e-05 -148.117936618498 112.125782333659 -1.32099802146962 0.187654597029269 FANCA ts 9.29558113238289e-05 1 0.299536396485542 4.24500465267638 -1.32099802146962 1.10111686906313e-15 176.145989455862 30.5093678942486 5.77350504495596 2.12162842634224e-08 -208.528417248351 59.8585507974726 -3.48368636510918 0.000576497596517401 SECISBP2 other 1.48177297069825e-11 1 0.000259093263424914 5.77350504495596 -3.48368636510918 0.0783729727502854 9.3502124526726 30.4714425879596 0.306851650547297 0.759191070289339 -69.4139399889835 45.0511711650653 -1.54077992189491 0.124532897827553 ADH1A other 1 1 1 0.306851650547297 -1.54077992189491 1.55665623780651e-09 182.902754479142 61.2998276222817 2.98374011108408 0.00310708451343966 -479.186847850976 120.268596134906 -3.98430565626183 8.70421912671107e-05 SEMA4D other 1.66437684946272e-05 1 1 2.98374011108408 -3.98430565626183 0.0963565629032286 53.363296091612 27.922954030377 1.91109064010773 0.0570596796580981 -10.2947963440232 47.5959233214456 -0.216295758661847 0.828921758439372 LIN28B other 1 1 1 1.91109064010773 -0.216295758661847 0.598302347421677 15.4339970973013 18.8457529525202 0.818964205685255 0.413534481836876 -1.66423185052119 29.0647375819539 -0.0572594831048638 0.954381162780459 FAM69C other 1 1 1 0.818964205685255 -0.0572594831048638 0.248585593930462 -160.607898496454 96.0311302849946 -1.67245660880814 0.0955799131198426 -102.193373205124 210.051404556701 -0.486516019356293 0.626991683921455 DNAH17 other 1 1 1 -1.67245660880814 -0.486516019356293 1.14017574925017e-18 306.750560621918 37.8663332958419 8.10087837724711 1.83289737206126e-14 -236.422148303185 97.2380771150159 -2.43137416244398 0.0156854102166361 MCRS1 essential 1.63307372565101e-14 1 2.66026724580971e-10 8.10087837724711 -2.43137416244398 1.86456032849743e-21 61.1805684480394 7.68062363186998 7.96557302901509 5.34339109072897e-14 -25.996667599837 13.936851710392 -1.86531851956583 0.0632762399611797 FANCM other 2.77390640070562e-17 1 7.69768920530415e-10 7.96557302901509 -1.86531851956583 8.12688107620002e-11 52.8345044488784 9.88645257819432 5.34413168231958 1.92875742175436e-07 -68.8415050606593 27.6982308206828 -2.48541163175137 0.0135435962598049 ZNF70 other 9.28496162955852e-07 1 0.00224179475130509 5.34413168231958 -2.48541163175137 0.0500066897127051 37.1571371099849 16.0686232816112 2.3124032755505 0.0215022540558987 3.00028907861038 30.2652056578895 0.0991332790705247 0.921105469356742 CARD9 other 1 1 1 2.3124032755505 0.0991332790705247 0.856536877980222 -3.75437715394076 15.4104054099414 -0.24362611197229 0.807704047644268 23.9005509635057 49.5486094353593 0.482365726018733 0.629934107086539 PEAR1 other 1 1 1 -0.24362611197229 0.482365726018733 5.86988575116642e-23 46.5365844331788 4.62421858027163 10.0636645144151 1.89883723497847e-20 -1.9950610454552 9.22011276795332 -0.216381414811921 0.828853242023619 ZFP69B other 8.85941856423548e-19 1 2.91262643473348e-16 10.0636645144151 -0.216381414811921 5.38696390916823e-16 45.2298576271185 5.1627815880815 8.7607536471296 2.12239562665035e-16 19.9364698661909 10.2994142407819 1.93568968099659 0.053941934403499 ZFP69 other 7.30526175722303e-12 1 3.1606715672077e-12 8.7607536471296 1.93568968099659 0.195341071545726 7.92301223955891 7.08266543811214 1.11864838298373 0.264284429096988 -20.2624614594043 21.1140432351958 -0.959667517665592 0.338081155387733 TMEM220 other 1 1 1 1.11864838298373 -0.959667517665592 0.0868992832833254 410.023466611024 184.668450482153 2.22032223447204 0.0272242113495275 275.650461863953 324.370231448799 0.849801970522267 0.396185316879473 HIST1H1C other 1 1 1 2.22032223447204 0.849801970522267 4.87287628507271e-14 307.468834846925 44.4724098469917 6.91369853589626 3.36071395743891e-11 -309.754722170208 129.458043690251 -2.39270356125066 0.0174034354870383 PLSCR3 other 6.27431550465962e-10 1 4.55410348372547e-07 6.91369853589626 -2.39270356125066 4.7642210394438e-11 765.450376551477 144.737352234462 5.28854759835259 3.11156676651359e-07 -478.356149980202 310.724655116544 -1.53948565748922 0.125205666317348 EIF4EBP1 other 5.50219887845364e-07 1 0.0035714563346043 5.28854759835259 -1.53948565748922 0.816824855112535 -6.58678581639505 18.5078267599944 -0.355891910044928 0.722198396852482 -25.1107204835138 41.1508943808332 -0.610210807355127 0.542233528923969 ASCL4 other 1 1 1 -0.355891910044928 -0.610210807355127 1.14432129186452e-07 33.4589467290135 6.47493214225101 5.16745905500432 4.58770664142296e-07 -19.7271066790685 20.5399091565161 -0.960428136694571 0.337689633374766 CCDC157 other 0.00109191137669712 1 0.0052020005607095 5.16745905500432 -0.960428136694571 2.55604785901073e-32 109.275606626225 17.0142344229269 6.42259909614118 6.13923433459979e-10 -256.482967802148 32.9155410106708 -7.79215409884952 1.4858916194962e-13 FAM122A other 4.02270812051109e-28 2.37296891633543e-09 7.99082740991508e-06 6.42259909614118 -7.79215409884952 7.87971916281565e-05 -1.21953282601173 6.06313784111318 -0.201138891770243 0.840741975815459 60.0042174397153 15.2423307392088 3.9366825498257 0.000105276441470058 PALM3 other 0.59113653159443 1 1 -0.201138891770243 3.9366825498257 0.753249759092462 -173.182566404788 1602.00734593198 -0.108103478329581 0.913993016958583 1243.70242884687 2225.68909063559 0.558794323106336 0.576760155648602 DMBT1 other 1 1 1 -0.108103478329581 0.558794323106336 0.0519565898740184 -4.08497963762268 2.93646766995567 -1.39112024948136 0.165329997675564 -17.4395684987012 7.24984504639532 -2.40550913669144 0.0168203052195516 CLEC17A other 1 1 1 -1.39112024948136 -2.40550913669144 0.00010785478440201 61.444713947228 274.089465516845 0.224177583152869 0.822788043811535 -1356.29828003019 407.171051686747 -3.33102826051013 0.000985487162783435 LDLRAD2 other 0.796184018455635 1 1 0.224177583152869 -3.33102826051013 5.12820103733063e-10 69.7496112503579 11.0906865588695 6.28902556033173 1.28675274649719e-09 -35.6797439187584 29.3363031450447 -1.21623177066144 0.224962788778361 PMS2CL other 5.6302519188853e-06 1 1.65708018693909e-05 6.28902556033173 -1.21623177066144 2.39125836235476e-08 227.973327785747 42.3176460322846 5.387193030818 1.57595185885523e-07 -222.045788827385 160.447227466944 -1.3839178920878 0.167543691708372 CYHR1 other 0.00023807368255604 1 0.00184228772300176 5.387193030818 -1.3839178920878 0.00644450333186396 587.678714140891 188.671828504958 3.11481962515378 0.00203805164304715 -221.761139271721 801.369488624151 -0.276727704785038 0.782200140901812 COL14A1 other 1 1 1 3.11481962515378 -0.276727704785038 0.49825710903089 -14.9951347425654 77.6542282413779 -0.193101329858755 0.847023193155309 -131.330010561743 120.491264799338 -1.08995461853983 0.276694269515288 DNER other 1 1 1 -0.193101329858755 -1.08995461853983 6.39417383426587e-10 7.85150694828236 1.30373194814278 6.02233224357749 5.5564120302817e-09 -3.88823047813311 2.86669211587781 -1.35634742796315 0.176113428758458 CPSF4L other 6.98627433131889e-06 1 6.97385273920656e-05 6.02233224357749 -1.35634742796315 0.000112823546440846 29.7179637201985 20.2227549027657 1.46953092509341 0.142897806160691 -81.4686263743153 31.8764173171925 -2.55576483278048 0.0111650036180236 KLHL17 other 0.830719772443948 1 1 1.46953092509341 -2.55576483278048 0.200188325076049 4.18698878729172 16.2221671422991 0.258102924878279 0.796525566423666 56.1522493359167 32.7136794650922 1.71647611195296 0.0872304086769895 ANKRD19P other 1 1 1 0.258102924878279 1.71647611195296 0.0111997693304355 5.34786008382025 1.91052711934276 2.79915423847005 0.00549179098665962 -0.144323958450952 3.47060352456423 -0.0415846861877067 0.966860402205137 ZSCAN23 other 1 1 1 2.79915423847005 -0.0415846861877067 0.000170329879407492 46.8333725318503 12.4064426585063 3.77492354746345 0.000197268074391347 -53.4581112586585 50.4582259779336 -1.05945284881868 0.290351071731223 RINL other 1 1 1 3.77492354746345 -1.05945284881868 0.000760784408963131 13.9789922585726 3.64226341193122 3.83799595954005 0.000154302568248162 9.49586807435167 8.06547601465001 1.17734750647123 0.240085998978517 C17orf99 other 1 1 1 3.83799595954005 1.17734750647123 0.0189832825740338 66.2197958432206 24.8711467280753 2.66251478338431 0.00823394435889215 -153.573850618533 205.620693466538 -0.74687935357793 0.455803555818463 TPRG1 other 1 1 1 2.66251478338431 -0.74687935357793 0.000804301500313752 46.4069944088582 12.2477431724888 3.78902412920437 0.000186239941486028 -12.5603013265257 45.097712514485 -0.278513047030744 0.780830165512313 MORN2 other 1 1 1 3.78902412920437 -0.278513047030744 0.409463729649964 -10.4715593745152 14.7337571455432 -0.710718879853586 0.477865187748745 -58.8083816947442 50.1968735958047 -1.17155467028248 0.24239735930979 S100A3 other 1 1 1 -0.710718879853586 -1.17155467028248 0.000266052847022665 48.9001618750982 17.5303187952888 2.78946221378701 0.00565266397278258 -79.8772795157997 36.5117164348244 -2.1877163638249 0.0295414225064901 RILPL1 other 1 1 1 2.78946221378701 -2.1877163638249 2.71794835881097e-12 16.795047850006 4.21445250552665 3.98510787059095 8.70008853005018e-05 -36.9605044980562 9.40055066423135 -3.93173823728106 0.000107438047496056 ZNF490 other 3.29388161604301e-08 1 0.820592350154333 3.98510787059095 -3.93173823728106 0.853550627660099 10.1166964903692 18.1903816649243 0.556156362011732 0.578562872128705 7.34090180123912 40.8797011291818 0.179573274717482 0.85762177962395 NWD1 other 1 1 1 0.556156362011732 0.179573274717482 0.0290698845420061 397.883275096798 253.394374776571 1.57021352761927 0.117523714866685 -383.853312614291 386.355608123014 -0.993523335869566 0.321334761320071 ARL4C other 1 1 1 1.57021352761927 -0.993523335869566 8.24568677917587e-05 17.4879432151938 4.15775067152102 4.20610676224033 3.52663646553158e-05 6.42741423768391 9.39567305621983 0.684082364214348 0.494503423803387 TMEM221 other 0.617437026024689 1 0.345680906351405 4.20610676224033 0.684082364214348 0.0267837387946566 -0.916173920775453 21.1258472085216 -0.0433674404501938 0.965440450681346 -69.9092962254926 30.6641350292456 -2.27983917233659 0.0233915819497491 RAB42 other 1 1 1 -0.0433674404501938 -2.27983917233659 0.000110360387253937 382.471879020091 167.225178185925 2.28716682002784 0.0229599669034097 -927.044594682141 373.876912480806 -2.47954490832523 0.0137655688162286 WNT7B other 0.813907855997786 1 1 2.28716682002784 -2.47954490832523 0.00812465568774045 28.1813698120228 29.8928313462023 0.942746757095096 0.34664703229818 -158.781072026801 63.5201153379536 -2.49969747665002 0.0130193960130534 C11orf95 other 1 1 1 0.942746757095096 -2.49969747665002 0.00532319279826519 12.2514398522114 5.24541586463635 2.33564700461757 0.0202340261677502 -18.4452795788506 13.624057404382 -1.35387565035641 0.176895774646006 PRSS45 other 1 1 1 2.33564700461757 -1.35387565035641 0.121602263907363 21.3365603414976 31.7283023131772 0.672477213904893 0.50185290527806 -74.5733215270603 55.489626250029 -1.34391464795677 0.180100039626225 PLA2G4E other 1 1 1 0.672477213904893 -1.34391464795677 1.0944497011186e-08 74.618281647305 12.0009257463624 6.2177104687047 2.07053333497658e-09 -29.9165316348407 40.685873770817 -0.735305128344057 0.462834758374822 GPR89B other 0.000111272701112728 1 2.64365696209809e-05 6.2177104687047 -0.735305128344057 0.486642798916778 -0.0853627674851181 3.34271902006925 -0.0255369257698931 0.979645420527835 -8.18937813390147 7.12926528753872 -1.14869875135881 0.251689376479154 MESP2 other 1 1 1 -0.0255369257698931 -1.14869875135881 0.523382611268494 -5.46315586394439 7.60802221802761 -0.718078326716654 0.47333683671867 -12.3739430122331 10.8612935841421 -1.13926973029249 0.255611739470841 FAM25A other 1 1 1 -0.718078326716654 -1.13926973029249 0.0133722379892219 14.0649669461733 5.63406277721739 2.49641644091156 0.0132145800087757 -9.27884204873685 11.4363715608726 -0.811344926959408 0.417968185087133 EYS other 1 1 1 2.49641644091156 -0.811344926959408 1.75314354775678e-10 228.598132012038 50.9085676003475 4.49036660796714 1.05294003880537e-05 -393.625836176296 114.985802529755 -3.42325598044538 0.000714435202108535 C6orf132 other 1.97018271896907e-06 1 0.107968471579103 4.49036660796714 -3.42325598044538 1.52827904889765e-10 324.280132598523 61.2729330067101 5.29238795477622 2.52705806287745e-07 -249.215430397161 130.669021159174 -1.90722658045766 0.0575683394542544 MAPK12 other 1.72267614391743e-06 1 0.00291849935681716 5.29238795477622 -1.90722658045766 5.37172069111541e-07 3523.90015175202 1163.39492961072 3.02898015287994 0.00270085668711117 -3901.10189196544 1833.81851084519 -2.12731078287974 0.0343356642059904 AGRN other 0.00489202603339881 1 1 3.02898015287994 -2.12731078287974 3.7144308943307e-13 125.020528318254 21.696666677165 5.7621997967934 2.2756139245704e-08 -118.960296768455 40.8431685825705 -2.91261184910174 0.00388610245791437 FAM166A other 4.64675304880771e-09 1 0.00027751111810136 5.7621997967934 -2.91261184910174 4.49655030825348e-10 30.129470883831 4.63837754241853 6.49569178194169 3.97971157204867e-10 -4.11168877837867 15.2351222482406 -0.26988223076802 0.7874577792096 TMPPE other 4.9529501645412e-06 1 5.21541201516978e-06 6.49569178194169 -0.26988223076802 0.137345472939188 26.7815033815643 13.5188559888777 1.98104805640345 0.048607974488831 19.8338677164804 30.4141317283659 0.652126711806876 0.514878335239268 ZNF626 other 1 1 1 1.98104805640345 0.652126711806876 0.394179379967593 -9.95066610476256 28.6196531600804 -0.347686467376274 0.728352704339247 168.304662555935 134.298945254423 1.25320911669925 0.211238393623951 HEPACAM2 other 1 1 1 -0.347686467376274 1.25320911669925 0.00359128726805404 -3.69123524805554 6.73732538434493 -0.547878429121535 0.584224700729937 -67.7993208210246 20.1576573873886 -3.36345238526787 0.000880393037496483 SMTNL2 other 1 1 1 -0.547878429121535 -3.36345238526787 0.133114439286436 -2.63373578208617 13.4534789180476 -0.195766150757709 0.844939373643332 -86.777617037296 43.5942541796817 -1.99057464498937 0.0475282950251643 ZC3H6 other 1 1 1 -0.195766150757709 -1.99057464498937 9.31216509113148e-12 540.170838124366 78.8455288718921 6.8510015197188 4.88939551368703e-11 -474.625585721386 347.647695553952 -1.36524876129296 0.173302955945885 LAMTOR4 essential 1.10554023961913e-07 1 6.59872818527202e-07 6.8510015197188 -1.36524876129296 9.26028627033516e-07 136.968665825849 29.0731502292708 4.71117387506049 3.97967345276091e-06 -104.224270041766 70.0472802973971 -1.48791315807359 0.137962752772109 PRKAR1B other 0.00826017535313896 1 0.0422243353337933 4.71117387506049 -1.48791315807359 0.00915630968564258 1.86865581877107 3.12208409576812 0.598528342431253 0.549989231311383 -9.6786516979073 4.75412159361714 -2.03584437362768 0.0427421213230791 NUTM2B other 1 1 1 0.598528342431253 -2.03584437362768 4.62442242106504e-05 75.7206819929176 18.5888202093221 4.07345281412452 6.08133849858485e-05 19.162774656745 35.0783270277554 0.546285307209282 0.585317637246519 NCR3LG1 other 0.355294374610427 1 0.583139548629302 4.07345281412452 0.546285307209282 6.9836744807253e-05 8.12320257505557 20.9388895446912 0.387948107645235 0.698360116892663 -154.053726460502 42.0341220783562 -3.66496833627996 0.000297763049880221 DCUN1D3 other 0.52677856608111 1 1 0.387948107645235 -3.66496833627996 0.841170200631084 -13.2622501869137 33.4354221390443 -0.396652691620324 0.691934610436214 22.118363805903 85.3809469084301 0.259055030504928 0.795788723629848 POTEE other 1 1 1 -0.396652691620324 0.259055030504928 0.000361374067878727 30.1779541312677 8.23467830580257 3.66473989761115 0.000298215306766288 -34.1517610807804 39.9670594172645 -0.854497718339216 0.393589624060259 ZNF793 other 1 1 1 3.66473989761115 -0.854497718339216 1.33390836231351e-18 2857.34815164045 409.997507320254 6.96918420386526 2.47318560474347e-11 -2876.59901527688 771.805068450398 -3.72710562921335 0.000236268593016582 TUBB4B other 1.90935642981555e-14 1 3.36427437813255e-07 6.96918420386526 -3.72710562921335 1.80047838764449e-08 41.3468141636427 11.5398760656732 3.58295131839708 0.000402679348296373 -33.9586882586389 18.1390254926117 -1.87213410513541 0.0622649747775994 AGAP4 other 0.000180623991848496 1 1 3.58295131839708 -1.87213410513541 2.73979354583117e-08 246.86188328787 51.1233103053597 4.82875388571991 2.39044493572837e-06 -131.905122908816 103.531322997875 -1.27406005341517 0.203820533391673 COMMD6 other 0.00027197930529466 1 0.0257857295217019 4.82875388571991 -1.27406005341517 0.387264402694781 164.82669491573 127.928968406526 1.28842354447784 0.198689431393907 218.030326200332 187.601120861949 1.16220161797847 0.246168581915037 PLA2G2A other 1 1 1 1.28842354447784 1.16220161797847 0.736501027803087 -2.39935091555068 34.6421312625598 -0.0692610653012515 0.944834050699362 -54.5211713334494 74.0206821466582 -0.736566723681711 0.462037426910568 IL17REL other 1 1 1 -0.0692610653012515 -0.736566723681711 0.00104865713672887 34.5615747219561 11.0123764089128 3.13843020240244 0.00188470826049297 -17.6822935847391 21.339844544776 -0.828604610855411 0.408052010556713 HYKK other 1 1 1 3.13843020240244 -0.828604610855411 6.03313493166033e-06 10.6874286319948 2.23890881198062 4.77349884676202 2.96033033689335e-06 3.18529502527365 5.61633394439906 0.567148438253073 0.571081087915264 OR7A5 other 0.0502861796553888 1 0.0317228998901491 4.77349884676202 0.567148438253073 0.000206654595238029 -0.164929660071251 5.10297228036103 -0.0323203127530183 0.974240401366001 -32.0338433004606 8.86942023131905 -3.6117178423168 0.000362367680221404 C15orf62 other 1 1 1 -0.0323203127530183 -3.6117178423168 0.0964769864601927 -1.34135895212056 5.45498101979913 -0.245896172186857 0.805947375056326 -15.7532198908479 8.10963101787301 -1.94253226270456 0.053100875601667 RUFY4 other 1 1 1 -0.245896172186857 -1.94253226270456 4.17694787709317e-13 40.0179137392807 5.51576641620382 7.2551864454809 4.29218840460752e-12 -44.1835083661203 27.143238771244 -1.62779057939574 0.104739954715809 ZNF383 other 5.21659020370166e-09 1 5.95970359979754e-08 7.2551864454809 -1.62779057939574 0.00164558962874934 -11.5015396041144 17.2584419885181 -0.666429774586041 0.505727343855964 -90.4161266101502 27.2038751256054 -3.32364878873624 0.00101626217676321 HES4 other 1 1 1 -0.666429774586041 -3.32364878873624 0.105089447084534 -43.7236965305765 32.026428752243 -1.36523796857976 0.173310501845131 -162.70665946685 79.5454113582768 -2.04545625811161 0.0417754311939387 IGFL1 other 1 1 1 -1.36523796857976 -2.04545625811161 7.04722726160388e-07 25.1918988279309 5.0382631884077 5.00011569183082 1.03249536546198e-06 -21.3005120555422 13.689849481695 -1.5559347152811 0.120894965523986 ZNF669 other 0.00635378009906206 1 0.0114400486493187 5.00011569183082 -1.5559347152811 2.57637063676567e-11 140.601572078395 35.308933633083 3.98203960333305 8.79880009391503e-05 -266.143383855436 69.5584381141886 -3.82618401262158 0.000161869565691332 CENPP other 3.00533634778715e-07 1 0.82946288485337 3.98203960333305 -3.82618401262158 8.15471103084558e-06 275.475926561627 61.6031504719543 4.47178308984443 1.14656614333343e-05 -501.61519885183 351.152284893987 -1.42848336869933 0.154317162925841 PLSCR1 other 0.0672926754265377 1 0.117190525510109 4.47178308984443 -1.42848336869933 4.61755391949712e-06 38.4486841825789 11.873442258812 3.23820871357199 0.00135148189097665 -74.9099778396097 28.2943699909689 -2.64752238213891 0.00857982253181971 C3orf62 other 0.0389398322031192 1 1 3.23820871357199 -2.64752238213891 0.000758476384704546 4.55617647794822 2.51423140210424 1.81215478978388 0.0710608629678965 -6.22504146012432 3.54389455519676 -1.75655380349732 0.0801150434257954 ENO4 other 1 1 1 1.81215478978388 -1.75655380349732 1.2240831188094e-11 61.3669961284433 10.1088942966755 6.07059430314005 4.25029728362903e-09 -38.9032307989245 26.6634774113403 -1.45904565255163 0.145702154325406 ZNF559 other 1.447600696304e-07 1 5.36132499356966e-05 6.07059430314005 -1.45904565255163 1.890995923694e-66 2595.74315655498 109.341651546341 23.7397471123331 1.88147510708577e-67 2168.82597002031 351.428376068608 6.17145944298162 2.53539858248371e-09 SBK1 other 3.01670579706903e-62 4.03432622444809e-05 3.00208168086606e-63 23.7397471123331 6.17145944298162 0.226989817865634 32.7507925072045 18.9659413648043 1.7268213518777 0.08533508371296 25.6942074927952 44.9883429704553 0.571130337244673 0.568382875788103 SLC38A3 other 1 1 1 1.7268213518777 0.571130337244673 6.91513176902007e-16 146.293413173652 32.017822953772 4.5691243088224 7.4355928045762e-06 -221.117514970059 50.5908621207961 -4.37070067005571 1.76415308972927e-05 GTF2F2 essential 9.34718361218443e-12 0.269880139666783 0.0771665821258918 4.5691243088224 -4.37070067005571 0.00175394243267042 54.8686114401763 18.379818808775 2.98526400129584 0.00309510738713073 -71.7238050915072 65.3287190310925 -1.09789088405929 0.273237546795278 FAM92A other 1 1 1 2.98526400129584 -1.09789088405929 6.3310371411658e-21 371.481940621132 38.7629768340649 9.58342137167014 9.72485568425936e-19 -226.551719273023 132.079981138101 -1.71526159620014 0.0875313874886858 FOCAD other 9.36233772435598e-17 1 1.47769182122321e-14 9.58342137167014 -1.71526159620014 3.86625394356099e-10 71.5276352061409 12.2906694527393 5.819669586037 1.67289644489336e-08 -41.0478202245696 33.5903700262033 -1.22201155249403 0.22277299462962 PRR19 other 4.27607686157845e-06 1 0.00020551532825515 5.819669586037 -1.22201155249403 1.06920099058128e-08 93.8418580475204 16.577084126529 5.66093875926838 3.84284381377075e-08 -44.5184351925398 55.4876425400145 -0.802312607900681 0.423077761967462 ZP3 other 0.000108759124761928 1 0.000463562249255166 5.66093875926838 -0.802312607900681 0.361166228743977 -35.5916333881927 87.8561727147777 -0.405112495666523 0.685715611188171 -169.533961161392 127.889534374712 -1.32562810546063 0.186083415097966 C10orf99 other 1 1 1 -0.405112495666523 -1.32562810546063 0.432205812184738 28.4456200916107 22.319068638092 1.27449852647805 0.203603237379708 1.76701139032704 148.385535855691 0.0119082455047742 0.990507779297177 H3F3C other 1 1 1 1.27449852647805 0.0119082455047742 0.710230702894994 9.52877378135389 28.3814882686767 0.335739045505599 0.737330343334244 -15.3906146870653 39.3803672525233 -0.390819480894484 0.696241169880665 JAKMIP3 other 1 1 1 0.335739045505599 -0.390819480894484 0.561858535572267 -9.10915186256498 8.73857237842259 -1.04240732560131 0.298169334163626 -10.5924934471588 14.0900677255844 -0.75177022945924 0.452853896119224 PDCD1 other 1 1 1 -1.04240732560131 -0.75177022945924 0.599521516555484 -68.6918467354663 73.4867299675732 -0.934751713211041 0.350745367854643 -112.009834565337 251.478002719869 -0.445406092596133 0.656380591775279 SELL other 1 1 1 -0.934751713211041 -0.445406092596133 3.24171635663328e-18 116.08152343651 13.5178897593266 8.58725181986489 7.20029926652451e-16 -18.9538388382899 24.3450940056808 -0.778548599313977 0.436927428405813 BLOC1S5 other 4.61134151731083e-14 1 1.06456424655565e-11 8.58725181986489 -0.778548599313977 0.678128163219392 10.0438099145809 12.4474067346485 0.806899792759486 0.420429203675462 20.6219030922451 34.1069963177033 0.604623840227797 0.545932989089884 CERKL other 1 1 1 0.806899792759486 0.604623840227797 0.048881084326607 17.8193338840491 8.41735886343611 2.11697447776094 0.0351766126599606 -3.31295684389719 15.9383772451863 -0.207860360746435 0.835494700165668 SLC24A5 other 1 1 1 2.11697447776094 -0.207860360746435 0.16148492904622 47.4570974951712 42.0303295848428 1.12911552119461 0.25984759377968 -73.9108929399227 77.9733737632258 -0.947899127263119 0.344025291758377 IER5L other 1 1 1 1.12911552119461 -0.947899127263119 2.42021694499848e-05 348.153369540275 104.999406774656 3.31576510986831 0.00103866747126117 -213.839580305463 188.716559106667 -1.13312568498346 0.258162953847502 H2AFX essential 0.19151176685773 1 1 3.31576510986831 -1.13312568498346 0.40779872390572 -20.3177725625109 16.5188341165413 -1.2299761847094 0.219768781129123 -34.7987751317289 33.9515142281103 -1.02495502550861 0.306295069535701 SERPINA5 other 1 1 1 -1.2299761847094 -1.02495502550861 3.40870795027411e-36 202.046796041303 13.6797689888171 14.7697520481867 1.27914134947722e-36 99.6282353380334 48.1737461278044 2.06810230356014 0.0395791553311061 C19orf54 other 5.39359858971872e-32 1 2.02922983681066e-32 14.7697520481867 2.06810230356014 8.1798273698901e-10 31.7665487487758 5.13135112685126 6.19067921166967 2.20859566918852e-09 1.14740045928884 10.316670964212 0.111218091889246 0.911525731243059 LCTL other 8.88492848917463e-06 1 2.81706377604995e-05 6.19067921166967 0.111218091889246 0.205702194646206 8.38718129376418 24.451186382261 0.343017355585207 0.731853309126522 -293.923292801829 175.894216994444 -1.67102306047454 0.095880063712019 NCCRP1 other 1 1 1 0.343017355585207 -1.67102306047454 0.449726642370473 28.7052580573286 44.4851919200358 0.645276704862319 0.519297868133456 -160.057858770588 175.356863409208 -0.912755027997287 0.362188702388812 KRTDAP other 1 1 1 0.645276704862319 -0.912755027997287 0.280237911479378 13.3522070838294 11.0656929334503 1.20663090545981 0.228638332249498 -10.7493146519665 24.1284969864247 -0.445502869822945 0.656316041350042 C22orf34 other 1 1 1 1.20663090545981 -0.445502869822945 5.35832027082422e-13 553.583711814849 90.7585842317572 6.09951903173414 3.64073492320042e-09 -343.644248117958 235.860994590522 -1.45697786407862 0.146275937915735 FAM83G other 6.67003707312199e-09 1 4.60625782483317e-05 6.09951903173414 -1.45697786407862 0.899122762375481 -2.64334077975724 5.8707750411137 -0.450254142126998 0.652884543105255 -0.817455310654141 11.4562192619164 -0.0713547193856166 0.943167690784755 CFAP77 other 1 1 1 -0.450254142126998 -0.0713547193856166 1.90656065418742e-08 347.276572333792 112.30988874964 3.09212818390318 0.00219384896708747 -414.504875317509 166.090668831307 -2.4956542004085 0.0131652790542671 SRSF10 essential 0.00019094204951687 1 1 3.09212818390318 -2.4956542004085 0.369533503500614 -356.549573048981 295.077676305863 -1.20832445718259 0.22801612165194 -32.1635307362238 539.072269731019 -0.059664598871451 0.952468425504039 HBA2 other 1 1 1 -1.20832445718259 -0.059664598871451 2.32561793198475e-09 12.7427346157049 5.27654367737432 2.41497756767284 0.0163936421014691 -33.3859529595228 8.47613068667052 -3.93881998681606 0.000104036234969661 DUSP28 other 2.46422476073105e-05 1 1 2.41497756767284 -3.93881998681606 0.000816658201317792 -67.251516232608 44.9154646679261 -1.49729089367814 0.135472850992203 -295.243472902409 77.9109895249623 -3.78949715184678 0.000185766406832855 C15orf52 other 1 1 1 -1.49729089367814 -3.78949715184678 2.5759281909381e-15 513.634736115348 97.3448594650677 5.27644437454519 2.70662847641682e-07 -718.681031668299 182.026730584911 -3.94821699735496 0.000100509226697148 NBR1 other 3.4334546857014e-11 1 0.00312020130761331 5.27644437454519 -3.94821699735496 0.00128947094149938 139.232898723693 65.8378503389823 2.11478500599303 0.0353714546995079 -499.957456103777 219.061198598222 -2.28227298719727 0.0232571099796268 RALGAPA2 other 1 1 1 2.11478500599303 -2.28227298719727 1.71559182110576e-08 83.7069073931329 15.4107946842323 5.43170609357209 1.24922276920968e-07 -19.9158360675461 29.0416424032861 -0.685768242408103 0.493449851239028 NDOR1 essential 0.000172296886593652 1 0.00146908597659058 5.43170609357209 -0.685768242408103 0.112164343254676 71.0669512134593 40.7995688019314 1.74185544848442 0.0826810434323922 -37.5847932899901 75.8584552297524 -0.495459513064919 0.620681802177287 NKAIN2 other 1 1 1 1.74185544848442 -0.495459513064919 0.817210849208774 -2.56573168551952 4.9698187171495 -0.516262630800973 0.606091978458307 2.39175485674092 11.3260606899225 0.211172703574599 0.832911220022271 CFAP54 other 1 1 1 -0.516262630800973 0.211172703574599 8.77660021459916e-09 79.4211888659824 37.0921431463155 2.14118630332827 0.0331747828827011 -299.196651295926 73.2274004000811 -4.08585651902501 5.82976906473493e-05 CLN3 other 8.9749513794491e-05 0.877671732695843 1 2.14118630332827 -4.08585651902501 0.64463449864113 54.3238180196254 58.0172397658138 0.936339237076825 0.357104876483809 48.8046387154326 67.0686226715497 0.727682137658321 0.472849705114067 FAM72B essential 1 1 1 0.936339237076825 0.727682137658321 1.06191920739059e-10 18.930642773268 3.91288574060907 4.83802595531996 2.20309821234856e-06 -8.11597403039429 6.04413940579477 -1.34278405667036 0.180465501124186 ASAH2 other 1.20591545191275e-06 1 0.0238176947737003 4.83802595531996 -1.34278405667036 7.95480562030564e-16 968.726481661928 114.088832311041 8.49098427987134 1.35099223130374e-15 -128.721545801206 257.337364154598 -0.500205425761163 0.617334885369682 SUMO2 other 1.07421695096607e-11 1 1.99068705282607e-11 8.49098427987134 -0.500205425761163 0.0356346130542079 13.5259774078265 12.4340670628444 1.08781602507557 0.277650025532029 -23.5239875725086 17.2997105528166 -1.35979081850468 0.17503474678917 NANOS1 other 1 1 1 1.08781602507557 -1.35979081850468 0.504473072985451 -9.63820618942993 8.44602694056534 -1.14115266944493 0.254813790273548 -14.4742788366006 20.8131899578142 -0.69543779045587 0.48737688413495 IGFL3 other 1 1 1 -1.14115266944493 -0.69543779045587 4.45114841713421e-08 202.051112777199 52.7070990556064 3.83347056463938 0.000157021012573938 -339.121567287467 122.307528205755 -2.77269577974769 0.00594364023341364 RTL6 other 0.000435856453005781 1 1 3.83347056463938 -2.77269577974769 0.0265779325935102 77.3418847914988 94.7812633777855 0.816003944611124 0.415209286336545 -261.44497192645 154.377537137637 -1.69354283514289 0.0914928022972547 DPYD other 1 1 1 0.816003944611124 -1.69354283514289 0.156142104216437 -580.887177078737 514.006326470181 -1.13011678488054 0.259418941991377 -2839.85398876447 1748.75806983083 -1.62392616666477 0.105545591066611 S100A16 other 1 1 1 -1.13011678488054 -1.62392616666477 7.78029445035493e-19 175.441528833029 32.0518721772412 5.47367491867147 1.01886298477778e-07 -288.427572334571 61.8767111459398 -4.6613268060466 4.97436304240791e-06 PTAR1 other 1.11818391840501e-14 0.0769931911703897 0.00120409227541038 5.47367491867147 -4.6613268060466 0.43982382703703 10.8668601336771 14.4479172400359 0.752140253376074 0.452621900412331 34.8166750205978 28.1384954714393 1.23733250258305 0.217038671967438 SAXO2 other 1 1 1 0.752140253376074 1.23733250258305 0.129311097348613 -7.04139427130316 7.38277835637893 -0.953759402138789 0.341055382321592 -21.6257863985289 10.6731643645221 -2.02618320677358 0.0437254879421341 LINC00319 other 1 1 1 -0.953759402138789 -2.02618320677358 2.51251406225263e-06 3.84254992579167 4.9525779645692 0.775868639177681 0.438503113376887 -27.1057995169982 7.27359281036567 -3.72660392514266 0.000236212465676779 RHCE other 0.0216302335619329 1 1 0.775868639177681 -3.72660392514266 7.37356687273759e-05 152.287738878724 41.4179984130743 3.6768493098076 0.000284301709448487 -82.9873770447032 96.4638219262968 -0.860295345835558 0.390381129723384 PARVB other 0.554713435836049 1 1 3.6768493098076 -0.860295345835558 1.14142674407677e-05 76.6298110511896 15.7891146198301 4.85333173495034 2.05601411853929e-06 46.5949201713985 68.0273687168242 0.684943737356034 0.493966998005813 SLC4A5 other 0.0929806225724941 1 0.0222913050732029 4.85333173495034 0.684943737356034 1.98524394583767e-10 222.910430931878 40.9186733514152 5.44764560222891 1.139723906744e-07 -22.7857218578784 56.5103147163084 -0.403213501327443 0.687106773055696 UROS other 2.22664960965154e-06 1 0.0013440764032232 5.44764560222891 -0.403213501327443 0.295210362329544 -7.44241174166408 49.2979619802428 -0.150967939499138 0.880114575922887 -188.033237036675 125.958734011845 -1.49281618707753 0.136661587429153 ZBED6CL other 1 1 1 -0.150967939499138 -1.49281618707753 7.02155035612691e-20 349.949049789322 50.6871125031419 6.90410308473637 3.67842983631142e-11 -246.49411569598 91.3836898034715 -2.69735350176916 0.00743417741504413 SMIM15 other 1.0246548434696e-15 1 4.97875478344751e-07 6.90410308473637 -2.69735350176916 0.0661488126594037 15.2700783940215 9.14364129926787 1.67002159142487 0.0960825890351095 -24.1726763865486 23.775058630324 -1.01672415460282 0.310201652277261 VWC2 other 1 1 1 1.67002159142487 -1.01672415460282 0.000889089938447584 -2.90400046114822 7.91801943183715 -0.366758440813075 0.714086467705091 -83.0181115978784 22.2862972030476 -3.72507423918432 0.000237745948870757 FAM221A other 1 1 1 -0.366758440813075 -3.72507423918432 0.0136658352566051 151.318286959177 58.0545033119066 2.6064866345716 0.00965202221911687 -54.8825854993871 120.301696998064 -0.456207907859106 0.648604523219203 TMEM120B other 1 1 1 2.6064866345716 -0.456207907859106 0.244451608569918 4.25793898724593 4.84118462762509 0.879524189792101 0.379902138075018 -12.8372402482323 12.1708388662174 -1.05475394008088 0.292484290715669 FSIP2 other 1 1 1 0.879524189792101 -1.05475394008088 3.04046855244146e-12 219.590079202056 31.1521453953101 7.04895526184576 1.47513845369888e-11 -169.773024168251 84.2034151987065 -2.0162249211343 0.0447557666414386 RBM34 other 3.67683862046746e-08 1 2.01990708464988e-07 7.04895526184576 -2.0162249211343 0.193308832342786 10.5246880112396 16.0963522136636 0.653855474304645 0.513765559644004 -39.9537214707671 30.3007847615141 -1.31857051839507 0.188438432562484 NOXA1 other 1 1 1 0.653855474304645 -1.31857051839507 0.00354687008300119 16.2808095261283 15.4592086633022 1.05314637254211 0.293218970286506 -49.1181045881387 22.95853478115 -2.13942679950408 0.0333012245648917 TMEM198 other 1 1 1 1.05314637254211 -2.13942679950408 0.00841112474792751 -13.3846841422692 6.73744434632363 -1.98661145892399 0.0479650929047805 -30.8809300980021 9.90258071029312 -3.11847295179359 0.00201235156418983 BCL2L15 other 1 1 1 -1.98661145892399 -3.11847295179359 1.76600185286133e-07 19.8639944494927 3.66739634779572 5.4163751516609 1.34967274408086e-07 -0.726769547804547 12.3323374906863 -0.0589320190396527 0.953050009825648 FZD9 other 0.00166463334650709 1 0.00158424586700212 5.4163751516609 -0.0589320190396527 0.00764203372524131 8.50941827999733 2.70549438068332 3.14523598376432 0.00184789069659907 6.17571362350518 14.4911716407585 0.426170759452955 0.67032807693589 SPRED3 other 1 1 1 3.14523598376432 0.426170759452955 0.840276444810615 -79.9707666804809 173.375563525589 -0.46125742898409 0.644982552504313 -202.190518948289 494.523238691695 -0.408859489562516 0.682964507292573 PRELP other 1 1 1 -0.46125742898409 -0.408859489562516 1.77668777528826e-07 45.0164770344694 13.5593892145077 3.31994873237393 0.0010233596079336 -87.1765011057177 30.0753556485757 -2.89860250114269 0.0040537383625785 ZNF548 other 0.0016739952218766 1 1 3.31994873237393 -2.89860250114269 1.64909105799849e-09 40.6495252398959 27.0521312759794 1.50263669894247 0.134101421891555 -193.070112757945 41.1392840315585 -4.69308392945871 4.28299711148168e-06 MTF1 other 1.76073452262499e-05 0.0663821722308546 1 1.50263669894247 -4.69308392945871 0.81397459360623 -3.69847463836495 13.3251368560556 -0.277556221622157 0.781564659268726 -25.2748185811399 39.4987865469799 -0.639888482424086 0.522785693247579 SHISA6 other 1 1 1 -0.277556221622157 -0.639888482424086 1.30215398044406e-08 220.552539681985 43.5200463362615 5.06783788734659 7.42669551539441e-07 -26.2570618485617 69.151815066294 -0.379701701587872 0.704462059825928 TMEM201 other 0.000131699853582112 1 0.00830675893396865 5.06783788734659 -0.379701701587872 4.71458958425223e-08 98.2974895143151 26.7581448502406 3.67355398008585 0.000288008558261718 -94.2959250597473 42.5738243022498 -2.21488030744666 0.0275970523258062 NHLRC3 other 0.00046075684006897 1 1 3.67355398008585 -2.21488030744666 0.295720880410076 25.200074078647 28.8272089585266 0.874176688936556 0.382796056196049 -51.5192090046711 60.8739018156927 -0.846326709279377 0.398117209647598 SNTN other 1 1 1 0.874176688936556 -0.846326709279377 0.0666021111784071 32.6478061726016 14.8504328589906 2.19844138434229 0.0287790908005828 91.4246043196476 85.9796937838562 1.06332786610615 0.288597645331808 ZDHHC11 other 1 1 1 2.19844138434229 1.06332786610615 0.244853884583875 -9.99243438123071 6.5891229259676 -1.51650447161195 0.130553139746094 -14.4191407423592 9.74439424675474 -1.47973700337108 0.14010070251538 CNR2 other 1 1 1 -1.51650447161195 -1.47973700337108 5.23627265627401e-05 10.2379120086301 2.93082352204066 3.49318610678464 0.000557229605830236 -6.9336692158466 5.81415982787207 -1.19254878109951 0.234089268263756 LINC00910 other 0.400260681845585 1 1 3.49318610678464 -1.19254878109951 2.06128189418526e-13 91.884364533491 16.4931616768244 5.57105825638048 6.08355622541199e-08 -60.6003345897063 29.5700931298409 -2.04937922662648 0.0413841569683686 SLX4 other 2.6025745195983e-09 1 0.000727349982310257 5.57105825638048 -2.04937922662648 0.831810859730124 -6.89496433403896 18.5124538366127 -0.372450048755966 0.709852157138805 -20.39775993563 34.8490062633262 -0.585318266509534 0.558826245811316 ENTPD8 other 1 1 1 -0.372450048755966 -0.585318266509534 1.25538602816886e-12 2165.01986507247 315.20054633725 6.86870594049034 4.37153466085796e-11 -532.133137398958 823.396141953875 -0.646266250575615 0.518649843149701 RPL14 essential 1.54111188818009e-08 1 5.90594332681911e-07 6.86870594049034 -0.646266250575615 0.0131525157871517 25.0712323228133 9.80769407681348 2.556282050241 0.0111275461728069 7.66311222162313 14.4012701026944 0.532113637684594 0.595084870060983 BEND4 other 1 1 1 2.556282050241 0.532113637684594 0.15156252322308 5.11779827612278 2.9531227606724 1.73301237059224 0.084231010949428 -7.83036443369122 9.86644494152787 -0.793635851626072 0.428101798113223 FAM78B other 1 1 1 1.73301237059224 -0.793635851626072 1.11382505585382e-06 9.75287669914423 2.47158374874388 3.94600292387457 0.000101569113082047 -7.53571583433362 5.41552759461842 -1.39150169631157 0.16522726064637 ZNF563 other 0.00988408354564676 1 0.952007296918031 3.94600292387457 -1.39150169631157 0.0355620382094466 65.9193950447692 27.2890402668492 2.41559961069236 0.0163711495368994 -24.9581798494072 62.6721875969528 -0.398233743010763 0.690771449161566 FBF1 other 1 1 1 2.41559961069236 -0.398233743010763 8.18411054892243e-06 91.4831572842152 25.1630223894877 3.63561880080168 0.000331370051375 -121.721069066324 69.4576268160786 -1.75245073357657 0.0808189547836207 KLRG2 other 0.0675270961391589 1 1 3.63561880080168 -1.75245073357657 3.5016683826583e-26 300.547110765613 28.4761121306963 10.5543590145382 5.41566769861878e-22 -403.709289268939 126.682254271459 -3.18678643343256 0.00160968204907171 MSL1 other 5.39852214554429e-22 1 8.36558189405643e-18 10.5543590145382 -3.18678643343256 0.850574129600946 -139.154535035397 282.624875759294 -0.49236478091869 0.622886794344491 93.8551512252097 796.035364085797 0.117903243322609 0.906237505425617 LRRK2 other 1 1 1 -0.49236478091869 0.117903243322609 0.0114432562934055 -173.423124276935 123.242038312387 -1.40717507314631 0.160521338786829 -532.718580510947 177.076167687944 -3.00841489550271 0.00287310980870387 GJB3 other 1 1 1 -1.40717507314631 -3.00841489550271 0.79220754194767 12.2096927770547 30.3836903776904 0.401850223764121 0.688137580272115 -43.3543333364298 103.442639456661 -0.419114724490318 0.675492170390931 HACD4 other 1 1 1 0.401850223764121 -0.419114724490318 0.0413617914521177 4.68861177839848 6.1802917024946 0.758639236479078 0.448722855227882 53.5387950791442 21.6999665142567 2.46722938691955 0.0142302503959065 CFAP126 other 1 1 1 0.758639236479078 2.46722938691955 0.626194304198521 27.6335418626599 31.8480335937305 0.867668698644547 0.386337768020774 61.7455696550097 82.8031901778128 0.745690709771162 0.456495833826638 USP32P1 other 1 1 1 0.867668698644547 0.745690709771162 1.81208754320068e-22 229.091726459386 37.6822447026466 6.07956686941465 4.14844041241208e-09 -413.209230224111 71.9628160034416 -5.74198250113433 2.53998533915672e-08 FAM120AOS other 2.72356757743062e-18 0.000402943274203821 5.23616148854653e-05 6.07956686941465 -5.74198250113433 0.802920429364774 0.434636679855717 2.62868952182065 0.165343482464481 0.868798755141585 -12.4075466221131 19.9341180743732 -0.622427667771464 0.534191886409225 UTS2B other 1 1 1 0.165343482464481 -0.622427667771464 0.0480921240079258 -0.689007219589013 15.2930040633102 -0.0450537524698646 0.964097522496096 -65.9874926123787 29.6140007727361 -2.22825322112943 0.02668129192079 C9orf152 other 1 1 1 -0.0450537524698646 -2.22825322112943 1.03430836949297e-15 773.614973556542 155.554370447054 4.97327700490329 1.19722970107416e-06 -811.773890582598 245.194883275044 -3.31072932575025 0.00106234527857599 NOC2L essential 1.39248935784839e-11 1 0.0132018519137448 4.97327700490329 -3.31072932575025 4.65273069208951e-24 496.984920818266 59.4903555413591 8.35404186604248 3.59179529289689e-15 -460.187876873465 111.988383126613 -4.10924654884229 5.27976624877485e-05 NELFB essential 7.0847130248447e-20 0.796294345640223 5.26629025844542e-11 8.35404186604248 -4.10924654884229 4.18455920827353e-24 406.299730417703 39.7242857407516 10.2279933506997 5.47235681647519e-21 -210.120342940753 105.511539843793 -1.99144418943966 0.0474321103683241 ZNF292 other 6.3747574978839e-20 1 8.41320136964896e-17 10.2279933506997 -1.99144418943966 4.32092297692621e-07 14.8841896470925 11.1781538288305 1.33154274623628 0.184133551797817 -125.575921041558 28.1335030103047 -4.46357216858357 1.18498430660666e-05 KCTD21 other 0.00396660729281826 0.182120238082378 1 1.33154274623628 -4.46357216858357 0.316869685248905 78.3352223005752 148.579046020387 0.527229272220705 0.598468924208429 -731.112536366362 580.54260108421 -1.25936069980213 0.208991719194687 SBSN other 1 1 1 0.527229272220705 -1.25936069980213 0.000832511806929786 36.7813584176993 13.9961395486876 2.62796453906093 0.00907587377362612 -42.4402233364757 24.6955546220423 -1.71853695881749 0.0868324199084206 ADAT2 other 1 1 1 2.62796453906093 -1.71853695881749 0.406794457625089 3.85468505373089 3.16847326679694 1.21657490190146 0.224820606295579 7.59819997371201 7.69531217818598 0.987380342444163 0.324333718750124 KIR2DL4 other 1 1 1 1.21657490190146 0.987380342444163 2.90060748213628e-14 47.6787040135734 5.99195236688276 7.95712333714322 4.88118191890487e-14 -15.5978034134493 24.2240812307944 -0.643896594667167 0.520189064365034 ZNF567 other 3.75947735759683e-10 1 7.03573561790949e-10 7.95712333714322 -0.643896594667167 4.28279981388577e-07 485.790106349232 114.49672444202 4.24282972911798 3.0330725971608e-05 -763.169918359849 291.303030853736 -2.61984887738102 0.00929283911800881 NDUFA4 other 0.00393289506909131 1 0.299212611709913 4.24282972911798 -2.61984887738102 0.00122852210036905 1.32748211044583 3.52056251121147 0.377065342887215 0.706419056679969 -16.9011474349613 5.5523818023679 -3.04394546998795 0.00256365662008255 ANKDD1B other 1 1 1 0.377065342887215 -3.04394546998795 3.50815542058814e-05 73.5374507494214 22.7810212645233 3.22801378812374 0.00139988402092304 -107.10359884642 49.0107531501718 -2.18530816121613 0.0297225424569027 ALKBH2 other 0.272864328613346 1 1 3.22801378812374 -2.18530816121613 1.69555468218915e-05 67.9616323608376 16.7493128805677 4.05757733737757 6.52862183158728e-05 -45.3812933084456 36.1968488455665 -1.25373602276995 0.211042873230241 RNFT1 other 0.136220863167077 1 0.624266819536376 4.05757733737757 -1.25373602276995 0.674210455808059 29.6910283321112 34.0141811548814 0.872901458274566 0.383495305367301 8.51504547097991 134.890795711274 0.0631254743963841 0.949713469476744 RELN other 1 1 1 0.872901458274566 0.0631254743963841 0.0339394897146146 93.8470740120631 49.765632962606 1.88578077732036 0.0603900108339254 -112.677409073487 118.470879455536 -0.951097937242688 0.342399012528546 FAM111B other 1 1 1 1.88578077732036 -0.951097937242688 0.375125180306786 -65.4551216699845 47.217928063634 -1.3862345163001 0.166823236558388 24.300645918409 364.490774133294 0.0666701262225151 0.946893841300825 APOD other 1 1 1 -1.3862345163001 0.0666701262225151 0.000459984477949486 1240.90001402354 456.973556244074 2.71547444500434 0.00704333166166144 -2062.64075695118 1110.95678895608 -1.85663454911631 0.0644482728704243 H1F0 other 1 1 1 2.71547444500434 -1.85663454911631 0.0146581728052973 336.279154857466 252.788445535498 1.33027897752646 0.184553060743735 -795.703375450274 492.025524864457 -1.61719938344555 0.107007265560234 LITAF other 1 1 1 1.33027897752646 -1.61719938344555 6.04619110789365e-08 119.638205048698 24.659954637231 4.85151764505158 2.07338661537834e-06 -148.623565681816 80.6313205714943 -1.84324856182945 0.066388679952787 TMEM120A other 0.000586964232754315 1 0.0224734375240859 4.85151764505158 -1.84324856182945 3.81653212257384e-08 140.314564492445 35.3551083204558 3.96872110306227 9.33606243735794e-05 -277.330498108478 89.8436444933866 -3.08681264737532 0.00224028644717972 ARID2 other 0.000375203272970234 1 0.878243393482262 3.96872110306227 -3.08681264737532 9.7561450911728e-18 1204.06132989856 206.586309870017 5.82836941448903 1.58028866415269e-08 -1233.99564169908 373.732240678248 -3.30181747087067 0.00108909555834777 SF3B3 essential 1.37561645785537e-13 1 0.000194391308577422 5.82836941448903 -3.30181747087067 2.08028432937756e-21 105.713369230115 12.7259046285628 8.30694338167876 4.68826984075761e-15 -118.935857325767 35.770041859658 -3.3250130875554 0.0010056694102712 BLOC1S3 other 3.09379885465031e-17 1 6.86597118178953e-11 8.30694338167876 -3.3250130875554 0.707666474101464 -12.2064858922683 28.5855097997075 -0.427016554114182 0.669707580154659 -49.3644233184152 60.4412117416793 -0.816734507729504 0.414800200964017 SP6 other 1 1 1 -0.427016554114182 -0.816734507729504 0.616862947354467 18.5402083705114 20.6440816294359 0.898088309439512 0.369929839586453 3.03928602221269 32.3999234466762 0.0938053457815958 0.925332592957535 ANKRD34B other 1 1 1 0.898088309439512 0.0938053457815958 0.0621241850618302 -28.5392748905601 20.4957282301318 -1.39244990810344 0.16493612967585 -74.0284908519476 31.2543644777762 -2.36858090346347 0.0185634317114767 PLAC9 other 1 1 1 -1.39244990810344 -2.36858090346347 0.000292595331845026 1624.49680471723 497.759788753067 3.26361598791807 0.0012417268992772 -2179.02981757227 1688.11529583674 -1.29080627546367 0.197875029948224 CLDN4 other 1 1 1 3.26361598791807 -1.29080627546367 4.45714326977247e-12 15.3225146827616 2.01899920947849 7.58916328982584 5.39032150533515e-13 12.743363487353 9.8919474508534 1.28825628630423 0.198772032837238 ZNF573 other 5.35035478103487e-08 1 7.6397026695115e-09 7.58916328982584 1.28825628630423 0.00660837823742154 4.6205874383124 2.0019134750642 2.30808548714336 0.0217532420015884 -3.2531654664444 5.06695729745964 -0.642035303529281 0.521397008957867 GRAPL other 1 1 1 2.30808548714336 -0.642035303529281 0.0693940267085515 -1.99346156629263 7.97979608887235 -0.249813597251246 0.802921463141519 -26.4719222141616 13.049316949537 -2.02860596585485 0.0434798086200328 FAM47E other 1 1 1 -0.249813597251246 -2.02860596585485 3.86217562376133e-09 988.320087495151 153.562474821038 6.43594790098908 5.51729920924234e-10 391.707625059343 346.373625735483 1.13088178762918 0.259100985562249 JPT1 other 4.02979404583257e-05 1 7.19235124916831e-06 6.43594790098908 1.13088178762918 6.13166441913187e-19 32.5290471269231 3.42639312052225 9.49367045249176 1.2663649376054e-18 -11.9839477038387 16.630019091131 -0.720621403870178 0.471768230197704 ZNF527 other 8.83143626287564e-15 1 1.922341975285e-14 9.49367045249176 -0.720621403870178 0.123130904962561 160.498529183101 96.8655052966302 1.65692140552623 0.0986841251814824 -372.435994343093 329.55690494901 -1.13011133661641 0.259421233399338 S100A13 other 1 1 1 1.65692140552623 -1.13011133661641 9.02397172994589e-10 77.4283540970549 38.8019634575594 1.99547515634729 0.0470634008975045 -289.405335133101 65.852341483219 -4.3947615014851 1.63289454298089e-05 ZNF33A other 9.7729613835314e-06 0.250110457148383 1 1.99547515634729 -4.3947615014851 0.460510128739716 2.56964621264158 19.7500957064498 0.130108038504462 0.896576765437051 -59.320272572402 52.6859880884603 -1.12592123114029 0.261187665367705 KRT77 other 1 1 1 0.130108038504462 -1.12592123114029 0.220428480630106 20.6475203780909 55.2739369141474 0.37354893700011 0.709031983414207 -87.4570219743424 78.973404551238 -1.10742372664965 0.269092734272101 PCDH18 other 1 1 1 0.37354893700011 -1.10742372664965 0.00366229923958139 19.9046967102 15.3520368453661 1.29655086883198 0.195896888807382 -95.6108911377079 39.1999544365466 -2.43905618034517 0.0153725550565516 ZNF600 other 1 1 1 1.29655086883198 -2.43905618034517 0.0366304294025342 155.466523621175 83.2819066890476 1.86675029189288 0.0630202721983874 -308.744316239687 254.215414166444 -1.21449880311955 0.225618423145404 PAX8-AS1 other 1 1 1 1.86675029189288 -1.21449880311955 5.93488664351024e-10 48.3107577467728 9.37722123622577 5.15192683735991 4.95901381193514e-07 -34.9736680862366 18.1106891158138 -1.93110642353739 0.0545089261727127 C15orf61 other 6.49454645399326e-06 1 0.00560566921301148 5.15192683735991 -1.93110642353739 0.111142743492298 -9.35252180647614 6.90739641941241 -1.35398654407499 0.176868690763619 -24.7497436441045 11.7649564029761 -2.10368341338211 0.0363276591113554 NUGGC other 1 1 1 -1.35398654407499 -2.10368341338211 6.72755416957438e-12 398.108601470087 83.112125010435 4.79001832067346 2.73947650574201e-06 -544.198859303247 150.813309690949 -3.60842726957214 0.000366324279251388 TSPYL1 other 8.02731763513615e-08 1 0.0294329355776921 4.79001832067346 -3.60842726957214 4.33004179827038e-16 351.952569540093 74.6463759902163 4.71493176823779 3.86675536048217e-06 -377.658548290809 110.391583965379 -3.42108098031505 0.000719563301257689 PNRC2 other 5.88625882056875e-12 1 0.0410649419283207 4.71493176823779 -3.42108098031505 0.072020586275677 -31.8158081874819 78.1256249987165 -0.407239086893764 0.684153879013515 -240.87777034812 112.252170301922 -2.145862923632 0.0327722112741585 GJB5 other 1 1 1 -0.407239086893764 -2.145862923632 1.53560779073485e-05 11.453337761541 6.50200847590253 1.76150766397628 0.0792718558141491 -54.7774641130666 15.2643738015558 -3.58858246169806 0.000393991484888825 FHIT other 0.123831412244859 1 1 1.76150766397628 -3.58858246169806 0.88800695679111 0.654739958132869 9.7697715127593 0.0670169161354265 0.946619348626521 -12.5985051236141 29.0007929738222 -0.434419332429503 0.66434151764493 ALKAL2 other 1 1 1 0.0670169161354265 -0.434419332429503 2.31106197558488e-13 44.0281884694 6.79192751095355 6.48242908929672 4.22768179091979e-10 -25.699947815191 12.3047421749336 -2.08862139895505 0.0376715755279551 ZKSCAN3 other 2.91216919543451e-09 1 5.53614930520947e-06 6.48242908929672 -2.08862139895505 1.39098472638059e-09 413.800463141645 81.8151760926542 5.05774702083418 7.82800166436293e-07 -383.149693995699 183.804468592911 -2.08455048415769 0.0380464315178264 RRP7A essential 1.4915529220979e-05 1 0.00874340529780703 5.05774702083418 -2.08455048415769 2.03409576508241e-12 83.1501312698627 21.8992988474018 3.79693120995642 0.000180963225722245 -100.378109845569 33.2638905576371 -3.01762987319964 0.00279087943218265 LIN54 essential 2.47854568975291e-08 1 1 3.79693120995642 -3.01762987319964 0.00313577103377611 11.3604412353851 127.992374538145 0.0887587348572816 0.929338729631069 -497.698445407366 178.366650810775 -2.79031109876791 0.00563689488117261 FAM53B other 1 1 1 0.0887587348572816 -2.79031109876791 0.677944366431163 -0.940692615851406 2.58425926160627 -0.36400860773803 0.716133337954375 4.17390711803375 7.04122978796958 0.592780983396559 0.553818439125102 FAM180A other 1 1 1 -0.36400860773803 0.592780983396559 0.0353070305131555 -1214.37561839362 534.249981140173 -2.27304756436669 0.023800528457913 -2506.06374914983 1817.63125804648 -1.37875255944005 0.169099720217378 S100A14 other 1 1 1 -2.27304756436669 -1.37875255944005 1.26872707528788e-12 283.899653769056 53.5482420252758 5.30175488553013 2.37572492615174e-07 -182.193776464526 89.9776332384691 -2.02487851599358 0.0438566345905995 KAZN other 1.55710873950081e-08 1 0.00274657558712403 5.30175488553013 -2.02487851599358 6.69124081296235e-08 414.459785257568 104.82922591914 3.95366637141117 9.85431083476794e-05 -252.499184033204 165.881334497744 -1.52216754704634 0.129146121190349 SLC35E2B other 0.000647912847919144 1 0.925418330493057 3.95366637141117 -1.52216754704634 0.495169739646822 -5.05442869449448 8.59574873652765 -0.58801494196959 0.557008361709591 -34.2899861644086 32.9682308762276 -1.04009178694311 0.299217518395266 TOGARAM2 other 1 1 1 -0.58801494196959 -1.04009178694311 3.50929920703666e-11 63.1395811760022 9.56408882061526 6.60173513235319 2.18209099205718e-10 -24.330123012873 24.0085739941713 -1.01339309110069 0.311789882510589 NEMP2 other 4.07219079984534e-07 1 2.8849425005988e-06 6.60173513235319 -1.01339309110069 2.86988219494619e-08 107.215568765783 17.611619123864 6.08777466806014 3.91600791803525e-09 80.8723553121435 66.559030907334 1.215047067388 0.225409600103751 ALG1L other 0.000284721012560611 1 4.94944240760475e-05 6.08777466806014 1.215047067388 0.396957677064122 7.32691973909279 29.807148123314 0.245810827281458 0.80601405440623 -65.5376775475177 55.4983400338196 -1.18089437463499 0.238676248048385 KIAA0408 other 1 1 1 0.245810827281458 -1.18089437463499 1.2390325545433e-07 80.8502460304152 14.2717968791368 5.66503620497892 3.77389850122623e-08 -19.1373186461989 61.7955574302823 -0.309687612540588 0.757038286093701 C8orf76 other 0.00117955899192522 1 0.000455509549098006 5.66503620497892 -0.309687612540588 0.0586937639044459 115.177660027239 190.960417224201 0.603149394526158 0.546919395468613 -1018.07531770631 524.952993590436 -1.93936472434064 0.0535063314183863 CXCL17 other 1 1 1 0.603149394526158 -1.93936472434064 1.75895980325376e-12 1290.86561272906 247.644232622577 5.21258096366173 3.71496934142661e-07 -820.893037646225 392.247597273821 -2.09279303009516 0.0373045645841765 HMGB1 essential 2.14856939967447e-08 1 0.00424026600630433 5.21258096366173 -2.09279303009516 0.0177933774434623 3.44508716042095 6.86642823399173 0.501729144035368 0.61626997928772 -22.5744075672717 10.8654077019143 -2.07764017573813 0.0386946394716507 MMP23B other 1 1 1 0.501729144035368 -2.07764017573813 0.713043698100285 12.5450585386563 20.9211839335182 0.599634254854841 0.54924917956504 24.8041003156716 30.6546087429085 0.809147509390725 0.419137521156399 SH2D5 other 1 1 1 0.599634254854841 0.809147509390725 0.000608618627517062 4.10944028530725 1.09642379615582 3.7480400368137 0.000217519232238532 -1.14130310070848 4.26278885960582 -0.267736249271802 0.789104514107599 SPATA41 other 1 1 1 3.7480400368137 -0.267736249271802 0.797023930421229 -16.4667120967561 28.6783889220357 -0.574185395892427 0.5663293993743 -27.660395987893 44.5431102131046 -0.620980345906679 0.53514629895471 RASSF10 other 1 1 1 -0.574185395892427 -0.620980345906679 0.224519147347236 0.734686946092571 41.1917871022922 0.0178357628492328 0.985782998784479 -86.8223616167404 59.1850305315701 -1.46696488684631 0.143545108401814 GJB4 other 1 1 1 0.0178357628492328 -1.46696488684631 6.75129537110456e-11 229.088457131413 49.4033549714264 4.63710323446477 5.49268964923277e-06 -128.506074022985 70.8342677280828 -1.81417946630424 0.0707518057485116 BLOC1S2 other 7.73833475436005e-07 1 0.057601836351504 4.63710323446477 -1.81417946630424 0.0646760288092044 97.3704444457246 45.9472927220779 2.1191769672849 0.0349883766221509 -55.9216977815182 136.489361662152 -0.409714699376641 0.682340114310395 SYCP2 other 1 1 1 2.1191769672849 -0.409714699376641 0.000471945490209915 142.942740384014 44.7297225630767 3.19569923963735 0.00156453817661106 -688.742065228853 339.589644891923 -2.02815979694566 0.0435479865678323 IL1RAP other 1 1 1 3.19569923963735 -2.02815979694566 0.188996566038545 65.8904622445357 36.0319297029685 1.82866870544286 0.0685647427165312 70.4577129502849 120.906092328933 0.582747416553668 0.560555169087607 PTPRT other 1 1 1 1.82866870544286 0.582747416553668 0.775983850550911 -31.8879613274495 109.363363364313 -0.291578096599166 0.770832286875355 -169.943757528852 240.63012563895 -0.706244727577631 0.480642680365808 MYBPC1 other 1 1 1 -0.291578096599166 -0.706244727577631 0.86805012862017 10.8510616784631 20.3952553429805 0.532038530333859 0.595146753034167 15.2865284296416 58.2162025482809 0.262582026317569 0.793077544898556 PAX5 og 1 1 1 0.532038530333859 0.262582026317569 0.486241853831257 38.4662417433273 37.7615150376103 1.01866256438639 0.309275088094243 5.85355936718148 55.3356745514144 0.105782741687602 0.915833277241764 SPOCK3 other 1 1 1 1.01866256438639 0.105782741687602 7.22021758442454e-11 16.9559724694605 2.83178744275903 5.98772782640076 6.68160445361329e-09 -8.43751340763325 7.46919478014066 -1.12964163554379 0.259618831283146 ZNF699 other 8.26642711240765e-07 1 8.35668269013415e-05 5.98772782640076 -1.12964163554379 3.14057878133825e-13 134.001029822828 25.8325954854103 5.18728479677967 4.19397789048899e-07 -167.682686132887 49.916842334676 -3.35924065486013 0.00089423550705731 TDRD7 other 3.93702956028563e-09 1 0.00476981105485312 5.18728479677967 -3.35924065486013 6.7305906286886e-08 32.681297413367 6.85737972812083 4.76585790915838 3.09247414785773e-06 -10.5539293938152 14.2745589011501 -0.739352400792215 0.460342548334753 CCDC189 other 0.000651541881346826 1 0.0330790772280697 4.76585790915838 -0.739352400792215 0.0322085918459281 51.2622387881012 35.7589739340688 1.43354892907769 0.152858013186218 -65.9009059898525 62.276177662179 -1.05820409125518 0.290908213625366 KIAA0895L other 1 1 1 1.43354892907769 -1.05820409125518 0.369713400125351 1194.69046108066 1161.47443177566 1.02859815799322 0.304579004845506 2931.60201390681 2281.66083229032 1.28485442376818 0.199932234367329 HLA-DRB1 other 1 1 1 1.02859815799322 1.28485442376818 0.897941211388892 -4.1807991528617 12.4800828552167 -0.334997708057212 0.737889848382406 -13.9222550286911 35.1366693871077 -0.396231494661797 0.692250725138605 MYT1 other 1 1 1 -0.334997708057212 -0.396231494661797 0.118061235531629 -965.598966693013 574.693894958327 -1.68019701473083 0.0940670527737113 411.445183296541 1181.18069434135 0.348333819937661 0.727858945244794 SERPINA3 other 1 1 1 -1.68019701473083 0.348333819937661 0.0358584186077365 5467.52454285689 2331.50955162455 2.34505774983732 0.0197567483049081 1709.03290440312 4000.46468160079 0.427208597107087 0.669571705759766 AKR1C3 other 1 1 1 2.34505774983732 0.427208597107087 1.31439569186563e-09 549.538613950673 101.620708078075 5.40774242124416 1.41748544548512e-07 -500.537863315419 234.982202820651 -2.13010967344387 0.0340769505724692 SPATS2L other 1.41126665435613e-05 1 0.00166143469065311 5.40774242124416 -2.13010967344387 2.6897539817509e-09 37.8218731546 6.79836487290516 5.56337793891276 6.63508112076054e-08 -45.7103492704295 25.3961281727269 -1.79989441538251 0.0730500360212256 ZNF250 other 2.83715249995084e-05 1 0.000791432476084318 5.56337793891276 -1.79989441538251 2.20346708609486e-09 76.1411141624162 13.2458535190578 5.74829806572044 2.41536843637607e-08 -29.8202955407348 34.6645819043747 -0.860252566235956 0.390407437009488 WDSUB1 other 2.33743788492943e-05 1 0.000294288490288061 5.74829806572044 -0.860252566235956 7.01900311412563e-12 25.7652962820789 4.68509673312694 5.49941607393078 8.80902361133529e-08 -20.8060567191289 8.69198139741273 -2.39370700049152 0.017359424569936 ZNF79 other 8.37156501421764e-08 1 0.00104439783935991 5.49941607393078 -2.39370700049152 0.981540004689818 -41.0091297299019 227.878168199092 -0.179960766114607 0.857317365855816 -61.8278691998777 776.506679855971 -0.0796231002305682 0.936595570860743 S100A4 other 1 1 1 -0.179960766114607 -0.0796231002305682 0.00262921669500892 178.172859506891 86.81768077957 2.05226467589329 0.0411080447486534 -177.382194657285 150.083232527338 -1.1818921519096 0.238288367179593 PLEKHG4 other 1 1 1 2.05226467589329 -1.1818921519096 0.0606386015889239 -50.5891063525296 39.6063997078785 -1.27729626337297 0.20259088601019 -140.012318461294 58.9557872048052 -2.37486979819145 0.0182514987533442 FAT4 other 1 1 1 -1.27729626337297 -2.37486979819145 0.888282813284378 2.5905484911748 15.3644581498822 0.168606563661646 0.866230967544727 -13.6988204180316 34.3159677243926 -0.399196680916977 0.690060386195794 KIF19 other 1 1 1 0.168606563661646 -0.399196680916977 0.0263438196150218 34.1315781738965 12.5701569903425 2.71528654734539 0.00706204520092799 35.6901744497657 25.9495429481134 1.37536813350158 0.170192149369036 ZNF681 other 1 1 1 2.71528654734539 1.37536813350158 0.123370948704666 58.0083052749721 94.476961082518 0.613994190862114 0.539730463820076 -168.715911249244 131.258038317817 -1.28537583992174 0.199750316921802 ACADSB other 1 1 1 0.613994190862114 -1.28537583992174 1.88634003502819e-05 257.390070880022 111.323166126283 2.31209801011268 0.0215193257317297 -375.901850690461 158.882335411214 -2.36591342717592 0.0186870220514109 STK40 other 0.150926066202606 1 1 2.31209801011268 -2.36591342717592 0.345569028257454 67.6645624405603 46.4816564383161 1.45572614285713 0.146630084055173 35.6070848922829 125.645264495746 0.283393767645643 0.77709217624892 TMEM63A other 1 1 1 1.45572614285713 0.283393767645643 0.03404759178897 -301.351812113817 115.218534488757 -2.61548034307988 0.00940582747392567 -104.968522125662 325.785867906035 -0.322200968385582 0.747547043831226 CTSE other 1 1 1 -2.61548034307988 -0.322200968385582 0.227959284829432 104.685757901283 61.2613845217272 1.70883760983487 0.0886217234708835 75.9210229735587 202.102574124553 0.375655893065319 0.707465527475465 SEMA4A other 1 1 1 1.70883760983487 0.375655893065319 0.0227554080437272 10.7463925087225 4.252848925236 2.5268690935515 0.0120887033038528 3.42363877883383 11.9390141565316 0.286760592955727 0.774518874112039 HRCT1 other 1 1 1 2.5268690935515 0.286760592955727 8.02994286891049e-19 235.432456007381 47.4377530911326 4.96297654644586 1.27340631512495e-06 -295.740216812262 71.1886704000886 -4.15431578016793 4.46047462229381e-05 MPHOSPH8 other 1.15309979597555e-14 0.674602181875715 0.0140176567168955 4.96297654644586 -4.15431578016793 4.60516413638498e-08 70.1185096676082 12.3591844910366 5.67339291022488 3.5781125623986e-08 -25.7120701913774 34.6925152927619 -0.741141712395293 0.459246889544366 RNF216P1 other 0.000450477155821179 1 0.000432450684291494 5.67339291022488 -0.741141712395293 0.401644747307794 27.182281916836 24.1292104503344 1.12653010229182 0.260937757827217 -29.0766177764711 74.5105974859555 -0.390234661344002 0.696669582572078 GREB1 other 1 1 1 1.12653010229182 -0.390234661344002 0.973530706434731 -0.693682757732964 6.35897586059233 -0.109087182109282 0.913213480289267 4.63883569582067 25.0877729754893 0.184904244005748 0.853441431113583 SIRPB2 other 1 1 1 -0.109087182109282 0.184904244005748 5.36236650979241e-15 88.827999925395 15.2561539772458 5.8224372969675 1.63675443593314e-08 -130.801033618019 35.2380285852325 -3.71192824540801 0.000249632018648096 ZNF766 other 7.09172970920046e-11 1 0.000201173487720542 5.8224372969675 -3.71192824540801 5.81597369360754e-06 150.959822298876 30.7622733728001 4.90730384160601 1.60827439376538e-06 -5.13913287902693 145.15597791236 -0.0354042110627352 0.971783880860003 RYR1 other 0.0485575643679294 1 0.0175832639470369 4.90730384160601 -0.0354042110627352 0.0835065807436993 48.7771159874603 24.6323533902406 1.98020526965913 0.0486955418620681 -25.8638292741748 69.2737045464122 -0.373357097668228 0.70917565363954 SRGAP3 other 1 1 1 1.98020526965913 -0.373357097668228 2.92994631701256e-14 280.725807991873 35.2192696623652 7.97080151528106 4.41541903022905e-14 -33.0264634765897 104.642635674343 -0.315611923034613 0.752540002383342 FAM217B other 3.79721042684827e-10 1 6.37056657681448e-10 7.97080151528106 -0.315611923034613 5.31581474285689e-14 8211.93744613061 1105.71227730107 7.42683030179886 1.44992429817847e-12 -2120.54461832334 2174.35017071912 -0.975254421702471 0.330303804747289 TUBB essential 6.83560617783967e-10 1 2.03467876763385e-08 7.42683030179886 -0.975254421702471 5.29767152012338e-19 487.935956589685 54.5416811170584 8.94611142517716 5.75348987424701e-17 63.6296969771941 85.5655698125483 0.743636688408551 0.45773581593234 LCOR other 7.63712326340987e-15 1 8.60952224782323e-13 8.94611142517716 0.743636688408551 2.50723731638687e-56 1358.8679881805 66.7257975817484 20.3649568447001 1.70831831789602e-56 -58.3488334936307 503.576240972714 -0.115868916652865 0.907842560937915 SUPT5H essential 3.99503193993083e-52 1 2.72305939872625e-52 20.3649568447001 -0.115868916652865 3.30736280168674e-22 181.123908428944 21.6405129673763 8.36966797885027 3.15188326160201e-15 -176.092233196043 51.4611001747815 -3.42185131289395 0.000718352668943436 XPNPEP3 other 4.96071346624994e-18 1 4.62381274477015e-11 8.36966797885027 -3.42185131289395 0.00263382175178221 57.9241440706259 18.5654120133275 3.12000315581708 0.00201980008662664 -29.9663006788088 55.831030095061 -0.536732004188111 0.591928160979512 ZNF107 other 1 1 1 3.12000315581708 -0.536732004188111 0.347188756719875 -106.907756938628 87.5341450541728 -1.2213263392527 0.22301614569809 56.1094409955669 172.452936193027 0.325360891117351 0.745157168623791 SFTA2 other 1 1 1 -1.2213263392527 0.325360891117351 2.16093806455634e-21 2202.00640068205 246.087719963413 8.94805478716873 5.76534506421483e-17 -2172.81551003532 709.734571681744 -3.06144803526584 0.00242315600634217 PPIA essential 3.21353099580173e-17 1 8.62668581958465e-13 8.94805478716873 -3.06144803526584 0.0856069252819711 19.0579955018977 9.84271302174526 1.93625430913137 0.0538686294533957 -4.92727309939262 22.4526917795942 -0.219451331170488 0.826462478242235 ZNF471 other 1 1 1 1.93625430913137 -0.219451331170488 0.000283316023437793 7.88764716317026 5.27383940120696 1.49561762562681 0.1359084063657 -37.7775148057898 12.6086576110551 -2.99615676554394 0.00298534761420057 ZNF836 other 1 1 1 1.49561762562681 -2.99615676554394 0.00106631849160997 37.8198417036456 10.8158506788506 3.49670523628796 0.000550864440506171 8.63394237753787 24.0747654577848 0.358630383863034 0.720152912572579 ZNF493 other 1 1 1 3.49670523628796 0.358630383863034 0.000758309122518876 21.1337531650003 11.0280101113474 1.91637049219374 0.0563815336623273 -97.981600464367 37.4679182963271 -2.61507991155121 0.00942594547882309 GTF2IRD2 other 1 1 1 1.91637049219374 -2.61507991155121 7.07648554596055e-24 77.461349971217 7.14408226201172 10.8427292870232 5.95390075976862e-23 5.39360370988906 16.5184388503736 0.32652018503353 0.744285667053737 SUPT3H other 1.07590886240784e-19 1 9.23985858908492e-19 10.8427292870232 0.32652018503353 1.9807682869827e-18 218.21939846785 24.8480446591474 8.7821557575765 2.03403164748726e-16 -74.7671394325668 56.0159238346844 -1.3347479486944 0.183104472193726 NIF3L1 other 2.8289332674687e-14 1 3.02948673576753e-12 8.7821557575765 -1.3347479486944 9.54114370944199e-09 23.4294277387734 5.39622485219394 4.34181828602782 2.01560696572431e-05 -19.5345699761557 10.8756145904298 -1.79618078718472 0.0736090296522227 ATP2A1 other 9.73673715548555e-05 1 0.201681632990374 4.34181828602782 -1.79618078718472 3.49483347764555e-20 930.874143488845 133.791219736458 6.95766243347271 2.61498199801358e-11 -1023.38291983635 262.817167428548 -3.89389677184834 0.000124397845986601 IARS essential 5.11993104475073e-16 1 3.55559102269907e-07 6.95766243347271 -3.89389677184834 1.58273744303723e-06 28.8993243101238 7.87826288851002 3.66823558937996 0.000294163863265319 -29.3506003797034 15.2233253797121 -1.92800190809942 0.0549035361015392 MFSD14C other 0.0138774419005504 1 1 3.66823558937996 -1.92800190809942 5.06830855613081e-19 768.690717139002 85.7039322841398 8.96914174941836 5.21843030934688e-17 -340.557945069653 288.196234323623 -1.18168769924742 0.238373234684782 POM121 other 7.30698044537378e-15 1 7.8109464870304e-13 8.96914174941836 -1.18168769924742 1.80975144569655e-07 431.120948570764 93.9279387127306 4.58991173956564 6.80073463051483e-06 -102.007830858907 172.300924152376 -0.592032987406934 0.554323919781259 ZBTB44 other 0.00170424293641244 1 0.0707888467690289 4.58991173956564 -0.592032987406934 0.0767380353181763 -73.6422972136297 45.1348756802568 -1.63160518565121 0.103915661950733 -241.856341465185 114.128779860215 -2.11915295827581 0.034980363655942 GIMAP5 other 1 1 1 -1.63160518565121 -2.11915295827581 0.00573668199083887 7.9780612553981 5.45402062802068 1.46278531005362 0.144689192886146 -36.4926300793903 15.5070027686032 -2.35330002992432 0.0193249929909985 STK31 other 1 1 1 1.46278531005362 -2.35330002992432 0.0587661838518395 1.13631118856818 4.7641706818093 0.238511855359607 0.811663713795481 -20.8104113297348 10.0143460782567 -2.07805993193292 0.0386416134189024 CGB7 other 1 1 1 0.238511855359607 -2.07805993193292 0.0389325148007555 1236.8454081805 629.706850781978 1.96416063545215 0.0505371848208334 -33.7262290770965 928.036146878787 -0.0363415037124643 0.971036910259437 ADH7 other 1 1 1 1.96416063545215 -0.0363415037124643 0.00251291693416319 12.8234409109682 6.33381273079384 2.02460057725151 0.0438853869280052 -33.5274529470768 16.6295255404083 -2.01614007961971 0.0447683017129418 ZKSCAN7 other 1 1 1 2.02460057725151 -2.01614007961971 0.273179817204364 -183.050178632844 301.815226593959 -0.606497494174166 0.544692165078331 1205.89183061816 845.604601684595 1.4260705632583 0.154998884549674 CD55 other 1 1 1 -0.606497494174166 1.4260705632583 0.0285181810615616 13.6879365825254 5.10971138515141 2.67880816562397 0.00783850081952415 15.7163553897146 24.9782420552057 0.629201821128125 0.529745023065787 CPNE4 other 1 1 1 2.67880816562397 0.629201821128125 2.0864851711452e-18 18.0086177071866 2.10859951615519 8.54055858839588 1.00380896046453e-15 -21.8015221056405 8.49709432775017 -2.56576204343644 0.0108372045505851 ZNF565 other 2.97804028477554e-14 1 1.48192316833378e-11 8.54055858839588 -2.56576204343644 0.517242990000744 -5.26290125350535 4.92560335709539 -1.0684784932843 0.286248595138748 0.0427308787500344 9.61181303336255 0.00444566270709966 0.996456132869118 NTNG2 other 1 1 1 -1.0684784932843 0.00444566270709966 9.64533112219236e-20 452.99972757661 59.9453945455191 7.55687290093033 6.26826977159502e-13 -377.438386664507 112.521747092549 -3.35435945865704 0.000908208804674585 WDR5 essential 1.4047460246361e-15 1 8.86897489982979e-09 7.55687290093033 -3.35435945865704 9.30280216242276e-20 748.464704110986 109.993208586121 6.80464470244962 6.44178981516971e-11 -544.754051349367 208.352731559564 -2.61457599942064 0.00943198719967775 LONP1 essential 1.35523221902175e-15 1 8.66613983834781e-07 6.80464470244962 -2.61457599942064 6.09764436435615e-11 479.063201597843 72.1454335743046 6.64024287974432 1.76514922393568e-10 -450.588976383776 325.809954553786 -1.38298099884911 0.16783484365871 TRRAP essential 7.00497384577235e-07 1 2.34217650524025e-06 6.64024287974432 -1.38298099884911 0.251495225195803 22.0097893061074 13.2102906356119 1.6661093925348 0.0969592617266509 2.64407795635101 44.5433791547957 0.0593596176698314 0.952713673865535 SRGAP2B other 1 1 1 1.6661093925348 0.0593596176698314 0.00236176210288185 63.720081082927 23.0962866392933 2.75888856412621 0.00619783451239115 -18.2456917161216 41.1706655180536 -0.443172134492718 0.65799742984948 FUT4 other 1 1 1 2.75888856412621 -0.443172134492718 3.82021391311608e-09 86.7294947608673 49.2758780796352 1.76008014754609 0.0795265276026139 -344.733681917211 84.734370967893 -4.06840433202525 6.21881469556378e-05 ASB13 other 3.98792130390188e-05 0.935123165771926 1 1.76008014754609 -4.06840433202525 4.33829883258542e-10 22.3785313366094 3.58729739433476 6.23827045171964 1.79295880553102e-09 -14.2979926192075 13.4187581020235 -1.0655227935774 0.287631705632811 ZNF34 other 4.78080531350914e-06 1 2.2946286793186e-05 6.23827045171964 -1.0655227935774 0.187293215838242 1.52949637016933 0.952973528797854 1.60497256634058 0.109677541509722 5.72360671001279 4.67947211003416 1.22313085224714 0.222354693269137 ZNF781 other 1 1 1 1.60497256634058 1.22313085224714 0.00316204751433127 56.5476067936181 20.5175532951223 2.75605994439217 0.0062516916143366 -59.625429822402 42.365517676448 -1.40740472659323 0.160466149560623 ZNF140 other 1 1 1 2.75605994439217 -1.40740472659323 0.000104762098194847 9.70607102298885 2.59571711370181 3.7392637940992 0.000225185899287395 -9.28321721248581 8.22435304325199 -1.12874741194417 0.260002616332698 INCA1 other 0.774506191954506 1 1 3.7392637940992 -1.12874741194417 6.75302550763636e-10 29.3812062926542 5.25149015453977 5.59483221486284 5.36493556437776e-08 -25.6713345151977 12.6788133611607 -2.02474267772072 0.0438670996674967 ZNF774 other 7.36755082883127e-06 1 0.000643684969014043 5.59483221486284 -2.02474267772072 2.98498652763981e-10 404.013238332301 69.6128216819994 5.8037187485071 1.81425484139156e-08 -458.07154188163 231.157706625182 -1.9816407965337 0.0485335657864531 PTPN1 other 3.31781252547165e-06 1 0.000222373215909363 5.8037187485071 -1.9816407965337 0.0827081038266648 18.027987844715 71.0493973289726 0.253738786287545 0.799891196582122 -294.507794252001 155.856064438846 -1.88961395446732 0.0598848498155584 EVL other 1 1 1 0.253738786287545 -1.88961395446732 0.211457074031847 8.42711480841792 6.89287529643133 1.22258338443768 0.222569237205143 36.4064498908806 27.0851105620855 1.3441499456843 0.180045159874481 THEM5 other 1 1 1 1.22258338443768 1.3441499456843 0.444748884625527 3.22175238667645 10.6312842824125 0.303044514763493 0.76208929508992 -16.5071585505666 19.4812934057585 -0.847333809247351 0.397559544687559 NOXO1 other 1 1 1 0.303044514763493 -0.847333809247351 6.43410883400374e-15 885.687835499846 114.710478417659 7.72107176011479 2.19255042174906e-13 -843.856134809079 490.254831335419 -1.72126021177696 0.0863364986086813 EPHB4 other 8.48787637381774e-11 1 3.13161976738418e-09 7.72107176011479 -1.72126021177696 6.41853262279398e-16 67.3037591568916 8.9864271701117 7.48949030385954 9.7733629659035e-13 -37.7094436108922 22.2505206018235 -1.69476680054855 0.0912683822753904 ZNF765 other 8.68684205168937e-12 1 1.37716457552546e-08 7.48949030385954 -1.69476680054855 0.000213797618278204 22.3626007368477 5.8461638519636 3.82517515812297 0.000162372627154769 -18.7175431370887 15.885058041996 -1.17831128395026 0.239709970623597 ZNF124 other 1 1 1 3.82517515812297 -1.17831128395026 5.55249038566767e-25 1991.79639709693 214.364896826873 9.29161642871762 5.27460944847534e-18 -1651.87543294191 497.778309501437 -3.31849620887738 0.00102943643490221 XRCC6 essential 8.50308377661147e-21 1 7.97098979853593e-14 9.29161642871762 -3.31849620887738 1.92531468612995e-05 138.264464336063 38.0131211883725 3.63728260173373 0.000329546068123999 -101.004804555394 70.9394998821632 -1.42381613520214 0.155645820882937 PPP1R26 other 0.153890402862367 1 1 3.63728260173373 -1.42381613520214 2.11614772800596e-07 128.574471017989 25.2727460467822 5.08747528978392 6.80188527651015e-07 -391.444319043352 165.073116476487 -2.37133900055197 0.0184257336029096 TSC22D2 other 0.00198515818364239 1 0.00762763414907849 5.08747528978392 -2.37133900055197 0.929894937713589 1.2070249345526 9.50801001873752 0.126948218625549 0.899075523129924 -3.62317763837917 16.1126103419033 -0.224865962838842 0.822253009430641 NPIPB15 other 1 1 1 0.126948218625549 -0.224865962838842 1.71393128350969e-07 22.5415084685523 4.0148962750443 5.61446845057127 4.90704551327347e-08 0.68086848896108 19.4863226005779 0.0349408404508754 0.972152827825812 ZNF569 other 0.00161640859347799 1 0.000590121293426268 5.61446845057127 0.0349408404508754 8.61370507889166e-13 60.6048865646569 32.7206326631268 1.85219177112529 0.0650897121941341 -275.308925025452 49.7596062612605 -5.53277941107402 7.44976163143698e-08 YRDC essential 1.06430939954785e-08 0.00117832879724439 1 1.85219177112529 -5.53277941107402 1.95185344824225e-11 116.663946815483 20.9518889324704 5.56818276344913 6.19292025339696e-08 -119.749498390528 54.034309580624 -2.21617522866376 0.0275102678634114 ZNF777 other 2.29030483616745e-07 1 0.00074011589948347 5.56818276344913 -2.21617522866376 1.46684029128951e-09 145.325196798961 25.3149243887833 5.74069250877765 2.52257900263648e-08 -270.408519608639 117.041775326529 -2.31035900518631 0.0216195813318173 PIK3R4 other 1.57142600405845e-05 1 0.000307073541990938 5.74069250877765 -2.31035900518631 2.70853692083193e-07 39.9262372365547 11.1249056169388 3.58890570503024 0.000394490741062499 -71.0356064496124 28.2322246121281 -2.51611792643137 0.0124480911846451 ZNF775 other 0.00252137701960245 1 1 3.58890570503024 -2.51611792643137 0.116440645390441 12.0730105478635 21.803571408741 0.553717109987929 0.580232421277235 -83.0218843752435 45.022402993155 -1.84401273268035 0.0662809294432631 ZNF605 other 1 1 1 0.553717109987929 -1.84401273268035 0.88384830504965 -0.159151147418885 1.80754843176058 -0.0880480681028667 0.92990349939 -3.33379794886762 6.71077845855848 -0.496782596751635 0.619745116719899 RFX8 other 1 1 1 -0.0880480681028667 -0.496782596751635 0.147958701146681 208.387449923225 133.614619660884 1.55961563526593 0.120013462318159 -214.717051791219 355.692983089175 -0.603658385179299 0.546573872567288 MYL6B other 1 1 1 1.55961563526593 -0.603658385179299 3.23168302338401e-08 20.681830269675 4.31986801929461 4.78760697718077 2.79437232272665e-06 -10.142536498093 9.46533350346276 -1.07154560316153 0.284888182882438 ZNF799 other 0.000319161015389405 1 0.030003175629116 4.78760697718077 -1.07154560316153 6.24221332296731e-13 102.889581531222 36.3007016332211 2.83436894886519 0.00494924142737425 -287.001445749861 63.9840013756871 -4.48551887314314 1.08932362565538e-05 SIAH1 other 7.75407738978999e-09 0.167516187153284 1 2.83436894886519 -4.48551887314314 1.44709085474997e-07 56.8288401799973 9.83724160863686 5.77690804402963 2.13591241006936e-08 26.4625120792983 37.3100007592679 0.709260561264529 0.478788696194314 C20orf96 other 0.00137126329396107 1 0.000260730827897167 5.77690804402963 0.709260561264529 0.123163258985359 20.3831397556363 13.2269335874442 1.54103289480376 0.124467071742445 -42.2317726291981 36.365490731955 -1.16131452591917 0.246528399646886 ESRRG other 1 1 1 1.54103289480376 -1.16131452591917 2.30993079091242e-18 453.740084511278 67.9396274775762 6.67857775141668 1.3548781223473e-10 -328.396308063518 135.310951416601 -2.42697508683121 0.0158751139582339 IPO4 other 3.29373031476202e-14 1 1.80415570771767e-06 6.67857775141668 -2.42697508683121 0.000193035180984286 558.525126733895 269.219544338392 2.07460839481945 0.0389702015547238 -1633.96539900884 554.102858211038 -2.94884853018845 0.00346887361707307 NCOR2 other 1 1 1 2.07460839481945 -2.94884853018845 0.946187763398099 20.2311046927048 64.337202793635 0.314454216444521 0.753424448578917 7.91057593633261 127.014664291748 0.06228080812907 0.950386337876056 SULT1A1 other 1 1 1 0.314454216444521 0.06228080812907 0.0245967915458287 5.48965173873554 3.1147572492117 1.76246535428239 0.079170182512827 -7.70339531255169 6.86266461887939 -1.12250790915229 0.262686050414162 ARL9 other 1 1 1 1.76246535428239 -1.12250790915229 3.68911048313604e-11 579.721838307507 90.94401049711 6.37449168052611 7.82916833579613e-10 -195.151569437138 212.99591707716 -0.916222114090768 0.360362006884764 PRPF40A essential 4.2764168720513e-07 1 1.01552142483612e-05 6.37449168052611 -0.916222114090768 1.02644544190209e-25 76.6085232430364 13.8738034752419 5.5218111875194 8.098635622493e-08 -135.849893034787 24.6920846041599 -5.50175877057782 8.96877570544713e-08 GDAP2 other 1.57949424599894e-21 0.00141796343903119 0.000961631993814819 5.5218111875194 -5.50175877057782 2.03404750427245e-06 196.611306238502 67.4504324636564 2.9149006026676 0.0038552039721118 -474.463731393207 144.137360059632 -3.29174706125402 0.00112778546845494 ANAPC7 other 0.0176692705324742 1 1 2.9149006026676 -3.29174706125402 0.0688980973425116 -3.10379796457642 4.49212635077556 -0.690941821803509 0.490197898621328 -29.3104085657999 12.6400772079452 -2.31884727313027 0.0211529496872597 TPK1 other 1 1 1 -0.690941821803509 -2.31884727313027 0.000580893049614669 90.3289888044833 37.3059222135799 2.42130427140606 0.0161219355731354 -107.362971674872 69.5338195301003 -1.54403961123401 0.123745644679232 SLC6A9 other 1 1 1 2.42130427140606 -1.54403961123401 5.80257998834458e-07 244.33762001661 106.063724329028 2.30368697273568 0.0219971931448691 -371.463041926287 160.87183744627 -2.30906197021809 0.0216925411597324 AFAP1 other 0.00526874262941688 1 1 2.30368697273568 -2.30906197021809 1.32513288923887e-10 2036.05845141988 379.21681847477 5.36911432253721 1.69772694590847e-07 -2543.17074974024 1014.9869343852 -2.50561919920743 0.0128083324657468 NACA essential 1.49766519141777e-06 1 0.00198056825509682 5.36911432253721 -2.50561919920743 4.90977277337813e-06 211.710606793284 70.8564857806822 2.98787901291886 0.00307571136664918 -382.445184659765 159.393651618213 -2.39937526229598 0.0171219968489189 MYO18A other 0.0412715499330165 1 1 2.98787901291886 -2.39937526229598 0.0947076030698085 32.6223156512769 22.055197992238 1.47912141449638 0.140356795759881 231.635454763319 140.495526350367 1.64870341982041 0.100454484692652 SPTSSB other 1 1 1 1.47912141449638 1.64870341982041 8.61854247906513e-09 37.2074820433195 7.15610562499674 5.1994036970823 3.92517865298522e-07 -40.3391178233784 21.3059966988179 -1.8933222600948 0.0593724204066774 BORCS6 other 8.81590710183573e-05 1 0.00447313359294196 5.1994036970823 -1.8933222600948 6.92712299034909e-09 427.437086746272 73.7488724923419 5.79584571670105 1.89158460142909e-08 -144.876873299406 177.44638982229 -0.816454329921831 0.414960088653967 MAN2A2 other 7.12662413247114e-05 1 0.000231624534444992 5.79584571670105 -0.816454329921831 0.173324522485901 179.351962001227 129.920891036366 1.38047053534312 0.168609513572423 -1050.81957085945 880.324493750337 -1.19367299026609 0.233677431575273 MME other 1 1 1 1.38047053534312 -1.19367299026609 0.482274271761898 29.1074103458678 36.7499201091109 0.792040098575661 0.429027499068004 -21.1515848049951 67.1984249762397 -0.314763103636342 0.753182847137476 CACNA1H other 1 1 1 0.792040098575661 -0.314763103636342 0.0113102614605545 769.707403323852 314.707295049702 2.44578824651107 0.0150923796948108 -1066.81980223167 1020.12100324402 -1.04577770562428 0.296599002219461 SULF2 other 1 1 1 2.44578824651107 -1.04577770562428 0.139811975405833 -44.5561093941679 70.5917883472242 -0.631179779367637 0.528454966968691 -263.212292321489 132.225767083564 -1.99062783394665 0.0475261050018179 LAMA2 other 1 1 1 -0.631179779367637 -1.99062783394665 3.78588654279052e-14 3301.38469350159 557.479759043205 5.92198127366581 9.83186821395577e-09 -3318.70557234851 1188.75130136758 -2.7917576775988 0.00562382723504012 PLXNB2 other 4.89022964732251e-10 1 0.000122101971349117 5.92198127366581 -2.7917576775988 0.81967761363681 3.88593163977372 31.8764874741691 0.121905892012809 0.903064567260255 -22.3620406404048 50.0945732550059 -0.446396469465287 0.655670015601494 AJAP1 other 1 1 1 0.121905892012809 -0.446396469465287 4.14458093734061e-10 93.0890027389584 15.7828871471533 5.89809721573968 1.10898691898534e-08 -21.3832390046762 39.6752072112943 -0.538957210501703 0.590365471690395 XRCC2 other 4.57354506435536e-06 1 0.000137447838739043 5.89809721573968 -0.538957210501703 5.3999226726624e-07 499.479091342776 113.712533374385 4.3924717576936 1.61735481860165e-05 -456.495216932809 263.242562911243 -1.73412388894999 0.0840503185468003 MYO6 other 0.00491608960119185 1 0.163207274745092 4.3924717576936 -1.73412388894999 4.3887225664469e-07 192.844174254029 49.6375893997503 3.88504310112608 0.000128768760539059 -297.984392823632 123.920478410697 -2.40464204662004 0.0168619075434114 MKL1 other 0.00402621408245839 1 1 3.88504310112608 -2.40464204662004 2.57520612934584e-16 1319.78121010304 176.780592838324 7.46564534552762 1.11679024145731e-12 -644.438924696373 322.244191182676 -1.99984652114659 0.0465074878347379 HDAC2 other 3.51953421697696e-12 1 1.57165890680287e-08 7.46564534552762 -1.99984652114659 2.86799914832306e-13 19.8160662869633 3.41282935022968 5.80634548446723 1.78914818961881e-08 -17.0554755749844 6.59467859847006 -2.58624818788609 0.0102266999619017 ZNF782 other 3.60306733003825e-09 1 0.000219385351011059 5.80634548446723 -2.58624818788609 0.647759885457539 10.1415361625142 11.1000019015882 0.913651750011243 0.361709018556247 4.00246987563393 30.5358836267802 0.131074309967691 0.895813416650433 POTEF other 1 1 1 0.913651750011243 0.131074309967691 0.0012408353378917 12.0991651726486 7.06326540171356 1.71297048666943 0.0878574766312889 -28.636037323207 14.040207775888 -2.0395736146003 0.0423590626994862 ZNF846 other 1 1 1 1.71297048666943 -2.0395736146003 0.306373501358447 773.812405379377 1241.24481798627 0.623416423711457 0.533535240239847 -2993.5632472561 2714.83557320323 -1.10266834455981 0.271149477089467 MMP1 other 1 1 1 0.623416423711457 -1.10266834455981 0.341740622549071 40.3740847607466 514.276787776678 0.0785065274582815 0.93748307356155 -824.271565455243 759.805015139533 -1.08484617636259 0.278953922381052 ADH1B other 1 1 1 0.0785065274582815 -1.08484617636259 0.993773367524063 -0.0240368055050884 2.75780744215988 -0.00871591146561815 0.993052720237799 -0.699939537621918 6.8529710777874 -0.102136654259441 0.918729754772583 UGT2B15 other 1 1 1 -0.00871591146561815 -0.102136654259441 9.7692501874442e-09 459.434871375122 138.185825207223 3.32476120966932 0.00100890958800819 -614.2049198341 230.828362542734 -2.66087283671819 0.008265852917374 TCF4 other 9.96658904123058e-05 1 1 3.32476120966932 -2.66087283671819 4.77698908243207e-09 144.75837990571 22.6112769083198 6.40204356846589 6.93556410784777e-10 85.6684785662994 96.401323159639 0.888664965982197 0.374989092580557 SDHAF3 other 4.95803696865624e-05 1 9.01137844532661e-06 6.40204356846589 0.888664965982197 4.35426771486818e-05 101.554109291201 24.5696395412265 4.13331702000752 4.77092466916297e-05 -36.9008551964051 70.0909102183315 -0.526471336746233 0.598991380891955 HRH1 other 0.335452784753444 1 0.461300706261367 4.13331702000752 -0.526471336746233 1.37118933106627e-14 558.037974831804 97.9289122780443 5.69839858169155 3.16016303239951e-08 -676.969201815306 184.360531370216 -3.67198552089156 0.000290083474238104 RABL6 other 1.79104750423877e-10 1 0.000382885353005525 5.69839858169155 -3.67198552089156 1.66850558024423e-10 30.7508761491358 8.5711392261237 3.58772332800419 0.000395955882289317 -67.1454336196362 18.6411129695274 -3.60200776259437 0.000375764270412292 ZNF136 other 1.87756932944883e-06 1 1 3.58772332800419 -3.60200776259437 6.47209028381829e-20 82.0623221785668 8.47154029876209 9.68682427097209 3.13849658842523e-19 -50.7979095475369 38.4611125549187 -1.3207602737701 0.187703812565937 ZKSCAN5 other 9.45119344145985e-16 1 4.78463804905426e-15 9.68682427097209 -1.3207602737701 7.05524950586124e-05 35.9566641099772 12.0092627297918 2.99407756487649 0.00300605615834838 -66.4545577910199 31.5305093116507 -2.10762715990967 0.0359783873443341 ZNF502 other 0.531754155256761 1 1 2.99407756487649 -2.10762715990967 2.28277492186005e-05 66.8574807750696 16.3402711472749 4.09157719431233 5.68446759644342e-05 -46.3532490028824 48.9949021171671 -0.94608310252427 0.344964815842509 TTC30B other 0.181275156544906 1 0.546675248749963 4.09157719431233 -0.94608310252427 4.25792632168036e-13 126.468135808961 21.7542932666376 5.81347940192169 1.72880437447874e-08 -107.639780225179 48.1841255594988 -2.23392619405872 0.0263099621623685 TECPR2 other 5.3164468052501e-09 1 0.000212210736967265 5.81347940192169 -2.23392619405872 0.266643287276911 5.57726202625012 4.750514484284 1.17403326412354 0.241408613531306 -7.52761313920239 10.0359736734434 -0.750063061556397 0.45386501580184 LINC00173 other 1 1 1 1.17403326412354 -0.750063061556397 3.47558149531668e-09 134.459729425876 27.2356438058494 4.93690291973191 1.38898863775725e-06 -71.7700363746797 44.6891711483969 -1.60598271416484 0.109442279835072 ZFP62 other 3.63650091854984e-05 1 0.0152469282766613 4.93690291973191 -1.60598271416484 1.22577234234982e-21 119.446047169243 17.7625232437531 6.72461032309985 1.04619273912001e-10 -141.737536098912 35.6576727172648 -3.97495196118856 9.04179445030087e-05 ERI2 other 1.82713625350664e-17 1 1.39719040309478e-06 6.72461032309985 -3.97495196118856 2.40653713716367e-12 618.778142877633 95.5518816826678 6.47583419584162 4.48335063528884e-10 -594.080697337182 269.639114561133 -2.20324376270154 0.0284285275071586 TOMM7 other 2.92346131422643e-08 1 5.86467096602133e-06 6.47583419584162 -2.20324376270154 0.0775327243850127 -37.9874753406432 18.4076322405765 -2.0636806974504 0.0399965530456046 -73.4080568984823 41.2530704926733 -1.77945680216749 0.0762814351409347 HSH2D other 1 1 1 -2.0636806974504 -1.77945680216749 0.000131649277711038 56.7238425408188 13.8430885014963 4.09762911901397 5.50778314383547e-05 -1.69509593223902 41.9101328884288 -0.0404459689200134 0.967767145230257 TRPV1 other 0.961171376568287 1 0.530069049762725 4.09762911901397 -0.0404459689200134 3.29155618065945e-10 80.1909488455661 33.0610280215485 2.42554311358072 0.0159721130844024 -198.403685308331 52.4622136499507 -3.78183975674685 0.000193505144765774 ZNF33B other 3.65099411558746e-06 1 1 2.42554311358072 -3.78183975674685 7.17446037427617e-07 242.92299294343 51.218946387771 4.74283463592351 3.42900396212835e-06 -203.706340165472 144.227489526161 -1.4123960753579 0.158993524722503 ZNF512B other 0.0064634713511854 1 0.0365188921966669 4.74283463592351 -1.4123960753579 8.62521321748745e-16 534.916153135109 66.3056505016503 8.06742938328907 2.3914294472063e-14 -238.930296844583 149.154950322371 -1.60189317436785 0.110352842136724 AMZ2 other 1.16405877583211e-11 1 3.4649421260572e-10 8.06742938328907 -1.60189317436785 9.11714401647537e-09 78.9423666011208 23.9443225313332 3.29691376725392 0.0011095509111559 -177.582808906919 53.5762467326265 -3.31458098946628 0.00104435754677792 ZNF431 other 9.31407432723124e-05 1 1 3.29691376725392 -3.31458098946628 0.737280955059066 -0.426350324787098 2.36851012310556 -0.180007811926965 0.857294026875709 5.05899147987887 7.75534548090135 0.652323161145736 0.514799320564581 ALKAL1 other 1 1 1 -0.180007811926965 0.652323161145736 6.55446949026723e-23 617.897965402843 81.5443717156077 7.5774446770871 6.02757380053569e-13 -621.974552845581 163.427889572804 -3.80580422638635 0.000175877268956265 NF1 ts 9.88807267301715e-19 1 8.53082519989817e-09 7.5774446770871 -3.80580422638635 4.12980181121121e-13 355.568108380609 53.0865139089567 6.69789899917723 1.35174615288705e-10 -341.72029312083 159.805037628598 -2.13835745225391 0.0334420899437641 VKORC1L1 other 5.15936140274616e-09 1 1.80012035179969e-06 6.69789899917723 -2.13835745225391 0.0914320858948428 -1.47969867150565 5.82138807024569 -0.254183135302161 0.79954754800626 -29.8348158931483 14.1251706131825 -2.11217384272192 0.0355899134698472 ZNF418 other 1 1 1 -0.254183135302161 -2.11217384272192 0.038442417105969 -9.69985810920421 110.271106347911 -0.0879637325719815 0.929969990856879 -483.28427310148 207.660312844245 -2.32728279410792 0.0206816730148056 DAPK1 other 1 1 1 -0.0879637325719815 -2.32728279410792 0.702286669140399 27.6469218273194 361.781303732626 0.0764188794226687 0.93914182287103 572.140616191212 710.702024942293 0.805035860475659 0.421499546283394 HLA-DQA1 other 1 1 1 0.0764188794226687 0.805035860475659 0.743440950679462 76.3383765739301 114.993831464895 0.663847578617592 0.507350164894483 136.785107184888 213.708587890016 0.640054330691118 0.522676046575726 COL27A1 other 1 1 1 0.663847578617592 0.640054330691118 0.00925045716505885 579.694191768198 383.588120343424 1.51124125337667 0.13188362651503 -1065.21342838099 640.124261253713 -1.66407288843376 0.0972452210515049 GM2A other 1 1 1 1.51124125337667 -1.66407288843376 0.0322541226884564 7.4212829985755 2.89898294800595 2.55996090066007 0.0110112301292786 1.71215004252878 5.12115393139675 0.334328955048967 0.738389932590722 HIST1H2AI other 1 1 1 2.55996090066007 0.334328955048967 0.231357314834732 536.907725478153 1863.09869762661 0.288179969296375 0.773427647476295 -10618.4857934068 6347.44613321937 -1.67287529039986 0.0954973536007096 S100A2 other 1 1 1 0.288179969296375 -1.67287529039986 1.5671251768876e-12 273.590406674679 36.8268410794024 7.42910330225692 1.44146405708349e-12 -30.6478629115997 134.347077635203 -0.228124522327302 0.819722104073484 SNHG17 other 1.91831792902811e-08 1 2.0235272433338e-08 7.42910330225692 -0.228124522327302 3.96099656669577e-10 75.5313094795044 16.0661821986922 4.70126060724325 4.13430438578361e-06 -76.0809298486793 35.0521589959347 -2.17050624064278 0.0308433778375707 ZNF700 other 4.37848560482551e-06 1 0.0437864177498342 4.70126060724325 -2.17050624064278 0.00142128160495571 195.239800095919 128.901462643904 1.51464379139962 0.131041111526891 -1488.33803861233 507.967909658701 -2.92998437561209 0.0036817440787158 CD47 other 1 1 1 1.51464379139962 -2.92998437561209 4.13561391440541e-10 116.975694444445 44.9556463689067 2.60202452623061 0.00977535302285937 -359.168006822611 82.7283419347914 -4.34153517914957 1.9979585708777e-05 TLE1 other 4.56447707732925e-06 0.305108253358734 1 2.60202452623061 -4.34153517914957 2.8114067183988e-06 27.826643975299 27.7404886292363 1.00310576166174 0.316707967325958 -139.783170674894 41.1856545168767 -3.3939771581781 0.000792235575322558 MAML3 other 0.0240993783901145 1 1 1.00310576166174 -3.3939771581781 0.0325779009606991 22.7091566981243 8.68647616876575 2.61431174816094 0.00944096315498522 10.9581934737974 15.1219538921723 0.724654601643096 0.469289133088105 HIST1H2AG other 1 1 1 2.61431174816094 0.724654601643096 1.19819243121772e-25 223.741363410656 29.7352434557459 7.52445036287137 8.26785228722323e-13 -219.065403986664 53.660694511847 -4.08241835070359 5.90543563721489e-05 STRN3 other 1.84281995921285e-21 0.888886172113585 1.16651127920433e-08 7.52445036287137 -4.08241835070359 3.8458038145444e-05 43.719114594097 12.7249206699052 3.43570822390225 0.000685905271370678 -8.59197986923926 20.3551448853083 -0.422103596788479 0.673291645265351 ZNF239 other 0.297934421512755 1 1 3.43570822390225 -0.422103596788479 0.847680064980323 32.8957700183096 57.319143218292 0.573905473308117 0.566506021322423 14.3959377011413 197.113409664267 0.073033781545665 0.941832912191512 SPRR2B other 1 1 1 0.573905473308117 0.073033781545665 2.16856133327537e-06 32.2937959283311 6.64829786547149 4.85745322814908 2.0096564069254e-06 -0.274295571135789 12.0571827484072 -0.0227495574098372 0.981866724944469 ZSCAN16 other 0.0187840782688313 1 0.0218168299535821 4.85745322814908 -0.0227495574098372 0.00631618081634923 75.6554717386351 36.6942936922635 2.06177757155157 0.0401753965863147 -98.4646706661676 70.4074667394818 -1.39849756319883 0.163098645504723 MVB12B other 1 1 1 2.06177757155157 -1.39849756319883 3.80280245258829e-14 816.60210328989 122.406044818081 6.67125634606951 1.40621666289667e-10 -434.477286084749 232.928140395442 -1.86528465537542 0.0632141734478351 C6orf106 other 4.91131936751777e-10 1 1.87125251331659e-06 6.67125634606951 -1.86528465537542 0.225863786982457 6.2137736673343 4.04193352637611 1.53732703093349 0.125393016270123 0.118560684196834 8.85634668816209 0.0133870870655175 0.989328929117853 ZNF709 other 1 1 1 1.53732703093349 0.0133870870655175 0.756800640776335 -8.08266865227104 12.131217734949 -0.666270182340025 0.5058031180745 -18.0389456440804 32.8824725267371 -0.548588480668924 0.58373788878443 POTEI other 1 1 1 -0.666270182340025 -0.548588480668924 0.150437193156523 61.3409455276811 40.5371234686068 1.51320420096373 0.131388840368426 -107.707718388649 138.525451099602 -0.777530176106089 0.437521773310334 ADA other 1 1 1 1.51320420096373 -0.777530176106089 0.525152211358402 12.9350208016981 41.4417235736301 0.312125550924934 0.75519055755908 -193.909562007124 188.230335534398 -1.03017168543318 0.303868728852264 ARID5A other 1 1 1 0.312125550924934 -1.03017168543318 1.73142890839114e-05 146.485584159945 66.1803138609049 2.21343139090912 0.0277009651729958 -478.153668609361 141.423195959026 -3.38101303231681 0.000828551390771491 PPTC7 other 0.139033741343808 1 1 2.21343139090912 -3.38101303231681 0.000152275946487311 18.7602591693125 4.47540634927357 4.19185604729672 3.74529752353488e-05 4.39135856516788 15.6324248124446 0.280913461465813 0.778990336232428 RGPD4 other 1 1 0.366065379950299 4.19185604729672 0.280913461465813 3.31595983643467e-14 119.774018771331 32.6056269659139 3.67341560082693 0.000287967324072272 -186.789163822525 45.9110328298863 -4.06850276086432 6.19842348475947e-05 NHLRC2 essential 4.29018883637918e-10 0.93211892363813 1 3.67341560082693 -4.06850276086432 0.0191855899980947 7.07894132651776 3.04087928765485 2.32792579279827 0.0206551219763722 -3.46186997387497 5.33148565069025 -0.649325572774782 0.516679934822301 HIST1H2AD other 1 1 1 2.32792579279827 -0.649325572774782 0.00361481966942086 27.848542388537 10.0964997244686 2.75823732466875 0.00620538866459747 -15.6847149995484 23.0338589599266 -0.68094169660568 0.496487655932567 ZFP28 other 1 1 1 2.75823732466875 -0.68094169660568 0.710911720702075 -17.3152268377081 21.3706565513032 -0.810233733163064 0.418514149243008 2.58113533485812 91.3663235175421 0.0282504016303397 0.977483154672776 KIAA1211L other 1 1 1 -0.810233733163064 0.0282504016303397 4.33626817735916e-05 74.6315030298013 17.6708724040912 4.22341927003685 3.28164408323881e-05 -5.38256779285387 44.72959173526 -0.120335723713097 0.904305719790069 SCN8A other 0.334162496475538 1 0.322388714737381 4.22341927003685 -0.120335723713097 0.000240243385599728 14.9475111996018 4.1014925150134 3.64440777226505 0.000320965727278893 -17.6718682594989 11.5559416599623 -1.52924519519914 0.12736576232992 HIST3H2BB other 1 1 1 3.64440777226505 -1.52924519519914 1.42716694037252e-06 55.2124649109998 15.4652623512573 3.57009558952041 0.00042152122568645 -65.5169252029614 28.0629017744295 -2.33464542368386 0.0202871782580203 KPNA5 other 0.0125576419083378 1 1 3.57009558952041 -2.33464542368386 0.00353521941971735 23.7585689497639 8.27108872050206 2.87248387154548 0.00439956962219925 -50.3732658826292 37.6023393899481 -1.33963116922707 0.181504389230028 ANKRD36B other 1 1 1 2.87248387154548 -1.33963116922707 1.46767011379162e-08 832.451188108716 167.708056473408 4.96369229727919 1.22186825766409e-06 -245.011264086483 303.456859990816 -0.807400643682593 0.420141179155348 ARHGEF12 other 0.000147882440665643 1 0.0134649881994583 4.96369229727919 -0.807400643682593 0.0316278944705467 26.6135775223043 16.7186225655818 1.59185228435583 0.112575111091792 -54.4985692899968 34.6771245227254 -1.57160001124896 0.117201573976654 HCAR1 other 1 1 1 1.59185228435583 -1.57160001124896 5.36390689519861e-14 156.352368017006 19.7212535837724 7.92811508420848 6.81046750140606e-14 -18.7295131544571 73.6711684505847 -0.254231248782487 0.799520201541543 ZNF252P other 6.89637509515686e-10 1 9.79140912677149e-10 7.92811508420848 -0.254231248782487 0.00139644515058165 153.70802716416 138.002675249948 1.11380469172621 0.266346245547531 -606.044163400536 231.064118932085 -2.62283978231456 0.00921186373893912 PDLIM7 other 1 1 1 1.11380469172621 -2.62283978231456 0.777059246487642 0.204912823630228 7.72208989366234 0.0265359282852177 0.97884955192864 -6.40288331353095 11.5808587283001 -0.552885020338278 0.580801299696838 TMEM26 other 1 1 1 0.0265359282852177 -0.552885020338278 0.00105250883998077 84.3406267840096 29.9761050609631 2.81359524903199 0.00525919095205015 -133.260540819871 88.3651345314928 -1.50806697150874 0.132706580217265 SRGAP1 other 1 1 1 2.81359524903199 -1.50806697150874 1.53012192170356e-09 591.352887781335 103.441336290461 5.71679474558243 2.87938815047862e-08 -278.654920510896 282.91437688425 -0.984944362247464 0.325536462261826 FAM3C other 1.63723045622281e-05 1 0.000349500133705094 5.71679474558243 -0.984944362247464 6.5251863856934e-11 201.155125357627 50.4042015369801 3.99084043043604 8.47320786623115e-05 -286.544258520303 98.7788644458209 -2.9008660924369 0.00402545647758626 NOP9 essential 7.48634634030604e-07 1 0.800463947122856 3.99084043043604 -2.9008660924369 0.0113671824090134 142.688153864731 48.6090805631981 2.9354217815171 0.00361549318483925 11.9874172548934 121.812132609724 0.0984090582610528 0.9216799636271 SLC39A10 other 1 1 1 2.9354217815171 0.0984090582610528 1.04568697705684e-11 498.34135863413 69.4871484095547 7.17170541661782 7.06905573133788e-12 92.330646538301 153.443940586856 0.601722337064446 0.547862026565527 CASP4 other 1.23966191130088e-07 1 9.75883143711194e-08 7.17170541661782 0.601722337064446 1.84214429754628e-12 422.270775787699 90.5213095153209 4.66487701126583 4.84093782329346e-06 -732.099005532296 188.282187481463 -3.88830730790386 0.000126829719964005 AP2A1 other 2.24852132958499e-08 1 0.0509944390305734 4.66487701126583 -3.88830730790386 1.82540143784789e-15 68.2456269746794 7.91034758227126 8.62738663059916 5.47125746915414e-16 14.1519459981054 34.2845694771668 0.41277887440093 0.680096221565554 ZNF585A other 2.44256966398426e-11 1 8.10347943756419e-12 8.62738663059916 0.41277887440093 1.80459090247387e-08 84.6541853818749 26.2447047675686 3.22557202039798 0.00141202051287749 -91.6054360210394 41.1331004088735 -2.22704914315863 0.0267687401262929 FUT11 other 0.000181000467518129 1 1 3.22557202039798 -2.22704914315863 0.0295074097890163 307.418553496399 115.553007710062 2.66041152531271 0.00826982619554424 -47.3149006391975 542.722113985973 -0.0871807125965395 0.930592252444031 ANXA4 other 1 1 1 2.66041152531271 -0.0871807125965395 2.12255986510843e-18 95.5653475275504 10.2828764379362 9.29363958658348 5.10650706824728e-18 -53.2437972252723 40.4811489918426 -1.31527386329873 0.189529636507555 WDR5B other 3.0284684155367e-14 1 7.71797478294894e-14 9.29363958658348 -1.31527386329873 5.83142135693068e-13 489.086448361015 107.732418362559 4.53982613399674 8.51244330382199e-06 -688.40998452798 207.687992253703 -3.31463546379247 0.00104416216187218 METTL9 other 7.2513724573433e-09 1 0.0878909771119621 4.53982613399674 -3.31463546379247 0.000145407144619569 35.9884084456682 9.65568667263764 3.72717235612589 0.00023891279417596 -25.2994291319935 29.0554055087245 -0.87073054700258 0.384726729265525 ZNF138 other 1 1 1 3.72717235612589 -0.87073054700258 0.0729336905667627 18.0401875785269 8.02397313921481 2.24828613774401 0.0253648226773911 10.2770080755736 17.4083598498433 0.590349014164373 0.555450460319652 ZNF429 other 1 1 1 2.24828613774401 0.590349014164373 0.00110472427637316 24.1356342876217 8.51566268164146 2.83426377839679 0.00493744121387181 -20.9250514145135 19.4273835994745 -1.0770905566038 0.282394160054344 ZNF470 other 1 1 1 2.83426377839679 -1.0770905566038 0.0330878240249969 74.23599820541 31.8957646069586 2.32745629773096 0.0206804714256164 -84.1335001408126 139.985131739324 -0.601017401601505 0.548332614265167 SERTAD1 other 1 1 1 2.32745629773096 -0.601017401601505 2.63512359777102e-05 42.2549545562487 10.7268875547017 3.93916262669574 0.000104253234548674 -10.7360538416701 22.9539036299134 -0.467722354104464 0.640361846676234 ZNF100 other 0.207726793212289 1 0.976018781844683 3.93916262669574 -0.467722354104464 9.55499642176779e-18 134.728518119217 17.0729124414678 7.89136115944574 7.42084571170249e-14 -79.2187970490147 44.0305425099628 -1.79917830971739 0.0731029111196673 ZNF398 other 1.34773224529035e-13 1 1.06644973722876e-09 7.89136115944574 -1.79917830971739 1.08788391717084e-18 98.7440726188865 11.0797097327519 8.91215338674407 7.76597961151658e-17 -118.066120720368 50.3023001814051 -2.34713164794824 0.019643925189554 ZSCAN25 other 1.55872007652239e-14 1 1.16101395192173e-12 8.91215338674407 -2.34713164794824 0.588278956203606 149.062652545115 218.068531993701 0.683558747253917 0.494833588745489 -130.850832524659 363.908449042098 -0.35957074607389 0.719446141970053 ANXA6 other 1 1 1 0.683558747253917 -0.35957074607389 0.029989903502339 4.08557512796314 4.83859606020561 0.844372019719605 0.399203586350467 -19.3572289696126 10.5810286820578 -1.82942788941085 0.068430145861889 ZNF441 other 1 1 1 0.844372019719605 -1.82942788941085 1.63628012780202e-12 358.688369841777 63.0155381184311 5.69206231592691 3.25598989167483e-08 -243.756751318438 121.310453374576 -2.00936312195438 0.0454900025179849 GMFB other 2.00117059630187e-08 1 0.000394235256083988 5.69206231592691 -2.00936312195438 0.468207596823543 -5.29397558500993 7.65935374450138 -0.691177841056167 0.490045425430751 -15.9823066876781 13.0914136696315 -1.2208235940747 0.223213939421576 SIGLEC15 other 1 1 1 -0.691177841056167 -1.2208235940747 1.63215923756493e-10 43.0615019399457 6.22441198704075 6.91816384095396 3.31497488610024e-11 15.0884078134947 26.9774852501406 0.559296304810918 0.576423145706906 ZNF420 other 1.8374848696506e-06 1 4.49278546313166e-07 6.91816384095396 0.559296304810918 0.409710800181758 0.885501621564134 2.43400013829603 0.363805082683375 0.71628933466211 -5.11089270840454 5.31034434867945 -0.962440921496078 0.336692514529863 ZNF763 other 1 1 1 0.363805082683375 -0.962440921496078 7.9242051074213e-14 62.6556038370092 14.6597989219909 4.27397430008543 2.65887799160725e-05 -78.8350168074114 21.040492996599 -3.74682365190561 0.00021867892779626 ZMYM1 other 1.01342659118811e-09 1 0.263680930427691 4.27397430008543 -3.74682365190561 0.918351406593027 5.7593146575356 13.9885228904227 0.411717141448776 0.680872201778011 6.22175804318761 22.0969617060481 0.281566222811739 0.778491023105894 DTHD1 other 1 1 1 0.411717141448776 0.281566222811739 2.47378542072807e-10 66.9331322697997 11.6539151820249 5.74340307307523 2.4784867148795e-08 -32.0627533542572 21.1130671539261 -1.51862129365202 0.130019300760018 ZSCAN26 other 2.76173404370082e-06 1 0.000301854897005175 5.74340307307523 -1.51862129365202 4.53479155948289e-09 393.214547865487 79.2810457921379 4.95975480566228 1.25734105040674e-06 -354.599170034081 176.304070632261 -2.01129315257679 0.0452993736470546 MAFG other 4.71210190945867e-05 1 0.0138470969881294 4.95975480566228 -2.01129315257679 6.36797782855012e-05 193.741340419615 56.7987406112161 3.4110147220651 0.000748229293662718 -147.05207818342 107.499198723702 -1.36793650491645 0.172490794394222 ARRDC1 other 0.483138477852098 1 1 3.4110147220651 -1.36793650491645 1.65588168565975e-09 736.649407598218 163.723997506067 4.49933680351851 1.01103969737462e-05 -1434.89908760428 475.235891749227 -3.01934073691859 0.00277385827506856 KIAA1671 other 1.76755261710386e-05 1 0.103783224935505 4.49933680351851 -3.01934073691859 1.30218711484671e-08 1146.23004539167 255.194487070286 4.49159407223392 1.04443335757929e-05 -1386.46628782349 505.155133112494 -2.74463466159561 0.00645962699428434 IGF2R other 0.000131699853582112 1 0.107127529486907 4.49159407223392 -2.74463466159561 0.080049611288642 33.803350459544 15.1911072592568 2.22520648973403 0.0268875742638359 8.66806159345524 66.9810134722329 0.129410726176137 0.897128304176368 GAL3ST4 other 1 1 1 2.22520648973403 0.129410726176137 2.03209032903416e-09 1845.99232051003 396.870277875666 4.65137457607333 5.16827170266739e-06 -1869.21177214439 883.808466272707 -2.11495119528265 0.0353502980789908 DYNC1H1 essential 2.1595023926646e-05 1 0.054300907176918 4.65137457607333 -2.11495119528265 0.453262171906022 -7.03455528177221 46.6460706686108 -0.150807027921988 0.880239311092524 -74.072544767087 69.2928629298808 -1.06897798178786 0.286023867030789 SLC6A17 other 1 1 1 -0.150807027921988 -1.06897798178786 2.75139719180936e-19 3022.1417668074 368.881661642704 8.19271349339838 9.95313557141335e-15 -2641.84014290354 998.320293540741 -2.64628512512125 0.00861046605555435 PCBP2 essential 3.98099659682897e-15 1 1.45027138411064e-10 8.19271349339838 -2.64628512512125 1.65129716542762e-08 170.009372880569 31.9688070639917 5.31797675591281 2.19727986873978e-07 -148.084293507756 89.5208664358992 -1.65418744705505 0.0992471823570182 ZGPAT other 0.000165955365125476 1 0.00254532899994816 5.31797675591281 -1.65418744705505 0.0416441934317852 107.62069340289 50.027704642927 2.15122189137067 0.0323459655948295 -28.3610261950017 110.296264272325 -0.257134966284782 0.797270430963704 SLC25A29 other 1 1 1 2.15122189137067 -0.257134966284782 2.97149866334228e-09 504.579988054569 81.7296771893286 6.17376705019522 2.43669957750133e-09 -57.9552829383499 203.733966353682 -0.284465491815633 0.776271724242114 PGAP1 other 3.12571944396974e-05 1 3.10264957203244e-05 6.17376705019522 -0.284465491815633 5.44266865856875e-13 502.235825292128 77.9587482356141 6.44232798318188 5.37411974986722e-10 -839.304417595534 298.372893534198 -2.81293789008128 0.00526964221456634 SRC other 6.77340114558881e-09 1 7.00946438975181e-06 6.44232798318188 -2.81293789008128 0.00559315972867222 24.1066472871709 7.58991288651919 3.17614281581385 0.00166565666338524 34.9312731464996 17.2908509522613 2.0202171219301 0.0443482431190212 ZNF682 other 1 1 1 3.17614281581385 2.0202171219301 1.30170998447696e-06 39.2509351150374 12.6840175525184 3.0945191421029 0.00217684649430547 -75.6810918577089 28.1337406065912 -2.69004726090274 0.00758604753226378 ZNF772 other 0.0114914957429626 1 1 3.0945191421029 -2.69004726090274 0.207840260126359 7.75593747671918 4.79776908319654 1.61657164866129 0.107142866034574 14.6510693077058 10.5748640859812 1.38546171265957 0.167059010031893 ZNF257 other 1 1 1 1.61657164866129 1.38546171265957 4.38680731645371e-09 410.245676618642 92.5057956014612 4.43481053215397 1.34238679116058e-05 -692.387316776569 222.085547577998 -3.1176603985606 0.00201993992103738 PCNX3 other 4.56315697057514e-05 1 0.136399921849826 4.43481053215397 -3.1176603985606 0.000651035559762515 6.7929068139174 2.41219565048258 2.81606793070804 0.00536917730843875 -6.7890867041934 6.11651079578128 -1.10996071630839 0.268404166427084 ADAM32 other 1 1 1 2.81606793070804 -1.10996071630839 0.013228626735784 30.2409391168968 112.271292614214 0.269355936078964 0.787860007453101 -370.608502241371 159.981111014697 -2.31657662514498 0.0212700498300332 ACSL5 other 1 1 1 0.269355936078964 -2.31657662514498 1.03527540968248e-12 370.419135521473 63.4830051566486 5.83493384737283 1.52598134022638e-08 -174.383554316435 112.267238508269 -1.55328978100402 0.121516657869003 LRRC8B other 1.27525224964688e-08 1 0.000187863562795269 5.83493384737283 -1.55328978100402 1.72042067733488e-07 83.8772085844043 24.8706014956307 3.37254443159084 0.000852556283841432 -178.629864941078 62.730010813523 -2.84759818505516 0.00473980091789444 ABCB8 other 0.00162235669872679 1 1 3.37254443159084 -2.84759818505516 1.17310893315885e-15 969.664992949971 141.912889123528 6.83281835031862 5.44868475066265e-11 -927.457824253369 379.243511049623 -2.44554698295685 0.0150975222029167 SND1 other 1.57747958241871e-11 1 7.34428217541818e-07 6.83281835031862 -2.44554698295685 2.24387891222569e-07 65.0189820477768 17.0559963309538 3.81208935474371 0.000171147210081969 -65.0442259877521 34.6826837993576 -1.87540924929682 0.0618277134349344 ZNF785 other 0.00210049504973447 1 1 3.81208935474371 -1.87540924929682 0.948072430572806 -2.35923153124826 15.2351120419391 -0.154854885527182 0.877054045298023 -9.81986735253495 30.077195734806 -0.326488793673381 0.744313245944486 SULT1A2 other 1 1 1 -0.154854885527182 -0.326488793673381 0.269214964193685 14.2879097627135 9.72386136199938 1.46936584457593 0.142893491376284 1.47580827531191 15.8906797141127 0.0928725707057842 0.926073417262042 NEK5 other 1 1 1 1.46936584457593 0.0928725707057842 3.47993762497688e-11 359.383219498165 50.5902036862389 7.10381048724502 1.07889686110869e-11 34.6781077000498 111.632690452214 0.310644736408053 0.75631038548539 PSMD12 essential 4.03846761378567e-07 1 1.48262006653557e-07 7.10381048724502 0.310644736408053 0.207286325341785 23.3011955097672 21.5426329615023 1.08163173700297 0.280374208860227 64.0350040433348 35.9910854145915 1.77919068863018 0.0763251449166536 PIWIL2 other 1 1 1 1.08163173700297 1.77919068863018 4.06655634525112e-10 115.170077804441 17.3987825672456 6.61943313328464 2.02751360362499e-10 -38.6130724804321 85.6573447306618 -0.450785307457822 0.652517126513194 NOL4L other 4.49110482769533e-06 1 2.68361700575803e-06 6.61943313328464 -0.450785307457822 0.000835669159101262 9.06261631126549 9.06618517311515 0.999606354626393 0.318399375976967 -51.7891145367919 17.0852258533416 -3.03122212028955 0.00267313675324976 CYSRT1 other 1 1 1 0.999606354626393 -3.03122212028955 0.0118527114916802 3.1455115032175 10.5571731154799 0.297950167986282 0.765967822401069 -41.5126744006884 16.9149922363007 -2.45419411494612 0.0147448086943485 SLC22A4 other 1 1 1 0.297950167986282 -2.45419411494612 1.32031461155495e-17 143.986383129677 59.4234655537407 2.42305597271941 0.0160412493918485 -567.36421654134 99.0805164202624 -5.72629450309679 2.70304780815812e-08 ENTPD4 other 1.85741859553551e-13 0.000428757443330041 1 2.42305597271941 -5.72629450309679 1.20472407387881e-07 90.0050682442033 15.4869382516584 5.81167605769753 1.74543203237355e-08 2.6947658361547 79.8159265403231 0.0337622571454245 0.973091771436136 C1D essential 0.00114798156999912 1 0.00021423432765353 5.81167605769753 0.0337622571454245 8.51815712044767e-14 825.90003396464 134.186713158754 6.15485702364234 2.68245292447094e-09 -481.404070638159 220.410219738809 -2.18412771970662 0.0298069527712496 TBC1D9B other 1.0884501168508e-09 1 3.40993415758746e-05 6.15485702364234 -2.18412771970662 0.00723157888212157 15.0021096337356 4.77345677339871 3.14281878854306 0.00185906274481905 12.757117105355 8.43247696170755 1.51285525751045 0.131481724816513 HIST1H4J other 1 1 1 3.14281878854306 1.51285525751045 0.232153367851869 13.639952656375 8.13306491129444 1.67709870819217 0.094676192928944 14.7116991691749 11.7049356191802 1.25687997335651 0.209879321057271 FAM110D other 1 1 1 1.67709870819217 1.25687997335651 0.123574801824806 -1627.03017212417 839.845011069497 -1.93729813320226 0.0537441308492358 -2531.42621408684 1726.15147301351 -1.46651452880174 0.14366333069932 SERPINA1 other 1 1 1 -1.93729813320226 -1.46651452880174 0.0386184645900537 -236.242154512816 136.521823127577 -1.73043509895156 0.0846867551610741 -633.795052195226 249.634596805111 -2.53889108443581 0.0116780984759918 TPSB2 other 1 1 1 -1.73043509895156 -2.53889108443581 0.292920082746137 -29.4394031609281 136.665580636908 -0.215411978815225 0.829608161341031 334.591260777537 265.563168099755 1.25993097300245 0.208778171493176 KANK2 other 1 1 1 -0.215411978815225 1.25993097300245 0.443751879406782 21.7828438044193 48.9833691912466 0.444698765398766 0.656897725185719 -124.76494806699 123.974131668332 -1.00637888233631 0.315144509701219 C6orf141 other 1 1 1 0.444698765398766 -1.00637888233631 2.6090717490795e-23 223.936506160059 42.8868492716 5.22156581710822 3.53788625891636e-07 -338.217428474613 74.6151111984856 -4.53282750694979 8.7406587336556e-06 GTF2E2 other 3.94987372093146e-19 0.134623625815764 0.00404628051432264 5.22156581710822 -4.53282750694979 6.82456967091838e-08 47.955680053291 8.77621595006904 5.4642775800103 1.05936278660829e-07 -21.8151766172944 31.6370779540502 -0.689544611198885 0.491074998100807 RAD54B other 0.000660277115661353 1 0.0012507896421484 5.4642775800103 -0.689544611198885 5.46492693199137e-06 52.4588050839836 10.9646508275919 4.78435710437529 2.82140060319163e-06 6.6949642090654 19.4043560686554 0.345023776381843 0.73034412643753 ZNF165 other 0.0457523682746318 1 0.0302792712734526 4.78435710437529 0.345023776381843 0.0265242593024097 19.8102343586635 8.54769671025406 2.31761081729756 0.0212239898767676 -4.27043064945927 16.0550597760348 -0.265986592951445 0.79045404477014 RAMP2-AS1 other 1 1 1 2.31761081729756 -0.265986592951445 3.34391432507143e-08 61.4882560373894 12.2345325576444 5.02579528459142 9.10009934937448e-07 -82.3076073567811 42.1806311159049 -1.95131284618797 0.0520462668295275 FITM2 other 0.000329843709025046 1 0.0101211304963743 5.02579528459142 -1.95131284618797 1.80538479515048e-13 146.963397166621 18.909913259096 7.77176474333792 1.58086819210013e-13 3.41169117229826 45.6547101550888 0.0747281312422916 0.940485752408373 BLM ts 2.28290907346778e-09 1 2.26143194879923e-09 7.77176474333792 0.0747281312422916 8.59938054927615e-10 351.762761261428 81.1170221101908 4.33648514344606 2.03888680361574e-05 -246.55864420525 125.99495580446 -1.9568929774292 0.0513791611266372 DDI2 other 9.32516826763505e-06 1 0.203929458097646 4.33648514344606 -1.9568929774292 2.36620871106195e-07 300.216373544711 182.979941389615 1.64070646905208 0.102009956781838 -1197.80517711172 315.268826554676 -3.79931371649264 0.00017891729643317 SVIL other 0.00221098541961628 1 1 1.64070646905208 -3.79931371649264 1.2570897224988e-14 272.365172751201 55.9862180353198 4.86486107311938 1.93809541442675e-06 -179.276667988716 82.3599496905723 -2.17674572000422 0.0303564924657787 TRIM33 other 1.64439906600068e-10 1 0.0210670971548188 4.86486107311938 -2.17674572000422 5.09942455028053e-07 185.799941749482 203.814813856161 0.911611566569478 0.362780442493711 -1575.74972098417 385.260750048959 -4.09008631370813 5.68478172561213e-05 LRP10 other 0.00465475472949607 0.856184975694443 1 0.911611566569478 -4.09008631370813 0.00553916674804847 240.42937920943 76.6358969543685 3.13729451555306 0.00189832035360424 -352.186574919083 478.895971929153 -0.735413525197044 0.462740514828499 PELI1 other 1 1 1 3.13729451555306 -0.735413525197044 1.852245844441e-16 405.725850155805 46.452743735982 8.73416331362001 2.66517230282952e-16 -180.608865605886 210.897209044201 -0.856383384229769 0.392547970481974 ZNF655 other 2.53868815439084e-12 1 3.96444380045891e-12 8.73416331362001 -0.856383384229769 1.34867398054567e-54 593.418440527398 29.390418504808 20.1908809304747 7.02849199805803e-55 166.692392258711 133.701146234155 1.24675365136195 0.213627358573624 MRPL21 essential 2.14884225320342e-50 1 1.12006048481053e-50 20.1908809304747 1.24675365136195 0.886675376265718 2.81465266966489 8.65513814628973 0.325200201555589 0.745279555452954 14.1987634953497 32.3661059317929 0.438692363093406 0.661232707647553 LYPD2 other 1 1 1 0.325200201555589 0.438692363093406 1.27118353462512e-07 192.710483748674 47.9979174419583 4.01497594102307 7.70911163572458e-05 -213.852272152858 90.3606642657166 -2.36665228051002 0.0186557576274157 UAP1L1 other 0.00120876842307503 1 0.732057240928406 4.01497594102307 -2.36665228051002 0.0282236966966834 2.10000694611054 2.39362515397677 0.877333254382621 0.381079893996822 -9.44100344450377 4.75069798087255 -1.98728765383855 0.0478933766029994 FBXL22 other 1 1 1 0.877333254382621 -1.98728765383855 7.66246488102426e-12 65.1697965084783 10.7651607848347 6.05376898785249 4.69872869787077e-09 -46.8431526828779 27.7630352283643 -1.68724897323259 0.0927060988466146 ZNF786 other 9.12522942681179e-08 1 5.91522955774951e-05 6.05376898785249 -1.68724897323259 6.00029292482729e-06 45.5828877005347 11.1028262044236 4.10552114040781 5.41742443247688e-05 -69.9665540857492 41.5039091704536 -1.68578226688001 0.0930466953227553 ZNF517 other 0.0500364427001348 1 0.521717694337059 4.10552114040781 -1.68578226688001 0.0128420452417459 37.3931969465751 20.6674238419289 1.80928195175994 0.0715489114154031 -49.1799780925545 42.6001668282665 -1.15445505861076 0.249361561968065 ZNF675 other 1 1 1 1.80928195175994 -1.15445505861076 5.23772108959503e-07 35.7911009121899 17.8075531263973 2.00988314667075 0.045427285618385 -99.5592637733044 28.5317498903994 -3.48942017772295 0.000564174491634964 SLC22A5 other 0.00477523031738379 1 1 2.00988314667075 -3.48942017772295 0.986322811115517 0.312057360458359 9.35312936946456 0.0333639521203611 0.973408915684743 3.66467803355173 22.7107710853625 0.161362994667921 0.871927742399661 DACT3 other 1 1 1 0.0333639521203611 0.161362994667921 0.112333846928464 83.3382278314927 64.5595479856232 1.29087378136618 0.197843539480939 -70.1245395730792 96.5055761870004 -0.726637178324263 0.468073112265428 ADARB1 other 1 1 1 1.29087378136618 -0.726637178324263 0.396465439216927 2.08495236240282 3.04859998753444 0.683904864832408 0.494617463397722 -9.25171911942138 9.76743260724149 -0.947200711941666 0.344377243698562 ZNF860 other 1 1 1 0.683904864832408 -0.947200711941666 1.06118149930214e-21 490.792536459824 108.745198554183 4.5132340828389 9.5130706878066e-06 -808.75722047469 171.418865860284 -4.71801756717883 3.81295945714537e-06 HTT other 1.5832827969588e-17 0.0591466270992389 0.0978609581654665 4.5132340828389 -4.71801756717883 0.863350537555416 21.2419651342204 54.9221122733816 0.386765261840002 0.699232403684326 -19.8044532071856 112.89061209798 -0.17543047060456 0.860871924418924 C5AR1 other 1 1 1 0.386765261840002 -0.17543047060456 0.9173862361848 2.26576340458823 6.56348112157487 0.345207575464858 0.730207101632582 -0.840499576622738 14.5484110817522 -0.0577726029254812 0.953972493897074 DIO3 other 1 1 1 0.345207575464858 -0.0577726029254812 0.759813549228378 -0.418662446922494 1.9450586570541 -0.215244124080341 0.829738889288924 -5.08121354021985 6.85288905236689 -0.741470276461702 0.459050404017303 CYP2B6 other 1 1 1 -0.215244124080341 -0.741470276461702 0.0229578516106677 8.74931248729409 3.52344398161921 2.48317059471833 0.0136294103174697 -1.39573726951 6.17755236298808 -0.225936938693124 0.821421402792339 HIST1H3D other 1 1 1 2.48317059471833 -0.225936938693124 0.188718791825336 69.9230744541345 41.0811901871411 1.70207031820663 0.0898805640608838 28.1356685649307 60.8988624948746 0.46200647125878 0.64444463796968 DCHS2 other 1 1 1 1.70207031820663 0.46200647125878 0.892082818455165 2.07451352634068 24.6403129332153 0.0841918498341886 0.932968437917695 79.1175103285692 166.671452356 0.47469143161709 0.635403863392213 VEPH1 other 1 1 1 0.0841918498341886 0.47469143161709 4.81034738695568e-17 136.197699739576 15.8983444295063 8.566785072715 8.05713672544224e-16 -51.2278884355921 47.695033288519 -1.07407176184786 0.283742419387885 SHPK other 6.69071218051666e-13 1 1.19020023708233e-11 8.566785072715 -1.07407176184786 0.00189335435298243 1.33610798417829 2.05110221951661 0.65140975006754 0.515364074939724 -17.4706389614681 5.76317711030979 -3.03142496353527 0.00268277484368509 GGT3P other 1 1 1 0.65140975006754 -3.03142496353527 2.66655727049534e-16 82.5251739055325 13.992459204874 5.89783201774755 1.08994037094512e-08 -69.5819256767409 24.5877810301416 -2.82993921214127 0.00500270413310219 IPP other 3.64278388722369e-12 1 0.000135109008382357 5.89783201774755 -2.82993921214127 0.00207909756035027 21.6589579251134 68.3620400380899 0.316827261343364 0.751619508181916 -411.183348251585 125.053271951271 -3.28806549269505 0.00114256992075264 MAP3K5 other 1 1 1 0.316827261343364 -3.28806549269505 0.0186258657223027 91.1004085928423 32.3650278036615 2.8147792470778 0.00524041421075703 66.3774647932671 50.1241148997957 1.32426208275126 0.186535921746679 OGDHL other 1 1 1 2.8147792470778 1.32426208275126 0.179157205809531 10.387438811633 5.90521289170121 1.75902867553357 0.0796928884698562 -1.41402187537051 20.7736132915126 -0.0680681716525565 0.945781193661691 CYP2F1 other 1 1 1 1.75902867553357 -0.0680681716525565 5.83926423335116e-07 237.929588014547 74.8416333302529 3.17910736881753 0.00164802432885701 -599.611524794554 203.200987028594 -2.95082978465149 0.00344531156821694 GSTK1 other 0.00530030014461285 1 1 3.17910736881753 -2.95082978465149 2.26197646281902e-11 1039.54364461694 178.793819625763 5.81420345956492 1.69805794304671e-08 -403.994711528464 301.731726523572 -1.33892022619936 0.181710446092596 HNRNPAB other 2.64538147326685e-07 1 0.000208572457144428 5.81420345956492 -1.33892022619936 0.00335529842542785 272.897652168945 84.3565031618674 3.235051738042 0.00136709285708234 -43.9373515459789 236.194083864155 -0.186022235727331 0.852566488880804 STMN3 other 1 1 1 3.235051738042 -0.186022235727331 0.0848767896901454 148.744208818441 72.549673458086 2.05023953559728 0.0413249156333483 -65.8297788735157 174.797270750754 -0.376606445803056 0.706767463467103 PDGFA other 1 1 1 2.05023953559728 -0.376606445803056 0.648144175591067 -1.97121999694232 14.0517617021944 -0.140282765870878 0.888540405647465 -17.7785343001288 22.0878812205572 -0.804899941402361 0.421580420685389 COL13A1 other 1 1 1 -0.140282765870878 -0.804899941402361 3.35731084451037e-06 30.6924517233203 5.97126090596347 5.14002858134501 5.27764843250882e-07 11.4624463760692 16.2249687961229 0.706469548268608 0.48050537590964 ZNF695 other 0.0285942164626948 1 0.00595793731545921 5.14002858134501 0.706469548268608 0.0123448785155032 79.4142736695932 26.6338809937022 2.98170115306783 0.00312522676399497 56.0341701245957 46.464035223026 1.20596865630876 0.228873702401402 PCDHB11 other 1 1 1 2.98170115306783 1.20596865630876 1.99807806813005e-09 25.9241077024369 8.76115287213591 2.95898360418824 0.00336134625836741 -79.7362644032285 19.3668709154582 -4.11714751191865 5.10723703552122e-05 ZNF628 other 2.12415679422906e-05 0.770784213400862 1 2.95898360418824 -4.11714751191865 0.000596853435527074 58.1674459268353 30.706581795459 1.89429895891041 0.0592579116607971 -278.091864868378 101.847790957882 -2.7304653567143 0.00674229349425436 SLC2A10 other 1 1 1 1.89429895891041 -2.7304653567143 0.840022193493727 -0.716138630399146 2.88216908242005 -0.248472108998488 0.803956642534132 2.96085048236215 7.32380434523825 0.40427765991417 0.686326250132224 ZNF665 other 1 1 1 -0.248472108998488 0.40427765991417 7.93260045495919e-14 176.092657210544 29.3641800753185 5.99685251755268 6.40826818508485e-09 -158.86917632958 55.1215270985765 -2.88216210057944 0.00426583721072457 RPF2 essential 1.01442094618018e-09 1 8.02187011408922e-05 5.99685251755268 -2.88216210057944 0.291747323797456 2.39766721679289 23.0272739990381 0.104122929048964 0.91714852840005 62.5655175824104 43.7163300111155 1.43117040168976 0.15352930842667 SLC28A3 other 1 1 1 0.104122929048964 1.43117040168976 0.243007687807232 -3.38897753516692 2.72767639201601 -1.24244120200129 0.215143901638178 -9.44784799496115 7.63583160404828 -1.23730439392511 0.217041190129297 FAM177B other 1 1 1 -1.24244120200129 -1.23730439392511 8.27310871545599e-07 201.064794935316 65.1304290803244 3.08710993884818 0.00223395112111281 -210.178375309661 103.329984950297 -2.03405018795617 0.0429349778184142 MIB2 other 0.00741187809817703 1 1 3.08710993884818 -2.03405018795617 2.54975074127223e-06 306.955089160498 88.4217194830828 3.47148970812794 0.000602150742974555 -349.460958584962 172.680549772196 -2.02374244838796 0.0439778743376862 MYO5A other 0.0219406051286475 1 1 3.47148970812794 -2.02374244838796 0.000394499360062006 -16.8591403359642 15.7180936684845 -1.07259446924963 0.284400325951304 -98.1542404102344 25.1839606553403 -3.8974902221911 0.000122361739205413 C5orf56 other 1 1 1 -1.07259446924963 -3.8974902221911 0.172962220205273 -7.93488703154961 5.27192477441498 -1.50512144445956 0.133461771646211 1.21931059027 9.2738280377102 0.131478671516434 0.895494574462814 GZMM other 1 1 1 -1.50512144445956 0.131478671516434 8.42995404415449e-10 421.423606573486 70.1697602224008 6.00577236173812 6.17865228605358e-09 -190.555310127978 199.912993787394 -0.953191218428915 0.341352105240752 ATG7 other 9.14818612871646e-06 1 7.74061558396793e-05 6.00577236173812 -0.953191218428915 0.0375735984097424 -9.49821718100465 4.0765702497948 -2.32995302398695 0.0205432418958715 5.11261614949609 14.0823005796828 0.363052622017762 0.716848589361053 PRAMENP other 1 1 1 -2.32995302398695 0.363052622017762 2.08553184990147e-14 382.662062853211 56.5195990268039 6.77043130953101 7.8893050007898e-11 -132.087117188877 103.713029883667 -1.27358266687451 0.203898616632968 SIPA1L1 other 2.71160851124189e-10 1 1.0577980145059e-06 6.77043130953101 -1.27358266687451 1.19732056822169e-06 100.610984533313 21.065231403438 4.77616327143182 2.95535854221061e-06 -47.5176156963 62.6307435766268 -0.758694739719378 0.448706911124497 TTC30A other 0.0106010763110349 1 0.0316725774968711 4.77616327143182 -0.758694739719378 0.149722195167982 15.1072320898477 10.4564425253567 1.44477742341268 0.14969735006978 -17.3379947555907 26.7179348325187 -0.648927204302048 0.516945297126209 SSPO other 1 1 1 1.44477742341268 -0.648927204302048 6.69276694474775e-13 252.356037459372 51.6137805571805 4.88931511575282 1.74242226769751e-06 -225.543634400892 94.68681542678 -2.38199619856581 0.0179145412090654 RAB40C other 8.30639305512644e-09 1 0.0189924027179029 4.88931511575282 -2.38199619856581 1.33547607601893e-16 251.540810062785 44.4073103039615 5.66440093626533 3.73811072666854e-08 -273.493494297684 78.7968651163454 -3.47086770385934 0.000602837247820201 PIGN other 1.83708089017164e-12 1 0.000451302108030693 5.66440093626533 -3.47086770385934 8.78254495084243e-10 20.8079723810639 4.24179356897499 4.90546558730629 1.60356486969875e-06 -24.1726125704312 11.0284372362632 -2.19184387167275 0.0292354357210456 ZNF624 other 9.51940047221811e-06 1 0.0175349818501558 4.90546558730629 -2.19184387167275 2.77130523280886e-13 40.0889068573794 10.3473612499158 3.87431209649763 0.000134152790372487 -58.1852730324681 16.2309802189246 -3.58482804166236 0.000399925962786823 HHLA3 other 3.48297641659417e-09 1 1 3.87431209649763 -3.58482804166236 0.00958880318621146 25.8816755542713 8.78369746940378 2.94655817147902 0.00349279119907055 1.92687719636232 24.5719374824709 0.0784177966323135 0.937553587050253 HOXA4 other 1 1 1 2.94655817147902 0.0784177966323135 3.13941279376836e-43 209.824068333678 17.4316656372118 12.0369488894831 8.81056238919235e-27 -213.806133525803 47.430793927964 -4.50774941382014 9.94648192274039e-06 TOPORS other 4.99009663569481e-39 0.153016677899438 1.38237723886428e-22 12.0369488894831 -4.50774941382014 0.0747148787941087 -7.68525159331986 8.33439288885953 -0.922112947614053 0.357289861339645 -33.4181011774687 14.775006757284 -2.26179938367837 0.0245022904762337 BCO2 other 1 1 1 -0.922112947614053 -2.26179938367837 0.00569547568512344 1.41804725370053 1.8424915051517 0.769635707809557 0.442198923033682 63.7192952193816 20.1214209356155 3.16673933830371 0.0017211857191948 KCNMB2 other 1 1 1 0.769635707809557 3.16673933830371 2.16257986713507e-08 318.72165938209 76.4940762896887 4.16661883954344 4.20680481344459e-05 -780.941294669801 252.9138234024 -3.08777624000125 0.00223414642274892 ENTPD6 other 0.000215803844941408 1 0.409448312492562 4.16661883954344 -3.08777624000125 0.275810599793653 10.0647500751277 6.2611442269737 1.6074937280262 0.109106248973867 8.75793913482712 11.0155811647738 0.795050120717524 0.42727754841582 DMBX1 other 1 1 1 1.6074937280262 0.795050120717524 0.177200210226823 44.6833945707067 25.184795386811 1.77422106808566 0.0771493253535569 1.64307510425899 47.0423847412133 0.034927547004638 0.972163227040059 ENPP1 other 1 1 1 1.77422106808566 0.034927547004638 0.103124551451519 6.9871960520652 4.14294002140985 1.68653082495928 0.0928401596854829 -1.13478877336549 7.57550066457836 -0.149797198048118 0.881035633616057 CCDC154 other 1 1 1 1.68653082495928 -0.149797198048118 5.12702690666974e-07 85.5929327327975 115.916511088568 0.738401560994179 0.460928864495726 -761.06615401516 189.110541371395 -4.02445124685302 7.47212328023116e-05 FAR1 other 0.00467789934964548 1 1 0.738401560994179 -4.02445124685302 3.04510216643397e-21 150.347356023513 14.226561421866 10.5680741512444 5.02351764798407e-22 48.9888928736712 95.7814648746726 0.51146527084099 0.609449601675913 C5orf42 other 4.52289024780437e-17 1 7.76183711790018e-18 10.5680741512444 0.51146527084099 7.74510046211763e-06 45.8379314530059 14.1534893482692 3.23863114777498 0.00134955673243173 -77.4514054218913 33.8380613473365 -2.2888842427135 0.0228499641845375 ZNF841 other 0.0640364906207886 1 1 3.23863114777498 -2.2888842427135 0.692698244632792 26.9513215739485 57.0996766769958 0.472004801820648 0.637301794395888 -164.73342508238 266.914432695627 -0.617176911037374 0.537634334073245 MFAP5 other 1 1 1 0.472004801820648 -0.617176911037374 9.81649903057983e-06 25.5609052460578 7.13576189945324 3.58208494148556 0.000403468834763148 -30.5037088386598 17.0601286348665 -1.788011655218 0.0748831040945848 ZNF615 other 0.0804976322993854 1 1 3.58208494148556 -1.788011655218 2.140952590409e-13 910.778032483049 113.806504896681 8.00286445234299 3.78028009909958e-14 -296.567659721637 450.608714968964 -0.65814896576526 0.51101160935517 CDC42SE1 other 2.70145397857808e-09 1 5.45721235106015e-10 8.00286445234299 -0.65814896576526 0.166123662640494 -123.359048099301 81.442028260238 -1.51468536251483 0.131017545228659 -309.236410395654 188.726671182525 -1.63854111587958 0.102469300358998 MPEG1 other 1 1 1 -1.51468536251483 -1.63854111587958 0.306911978270864 43.2719413025002 242.53075000268 0.178418370874712 0.858527236527258 -536.50525848125 429.512460571416 -1.24910289626404 0.212701331002637 SERPINB2 other 1 1 1 0.178418370874712 -1.24910289626404 0.559858845159918 -48.9700155358573 51.7001017789873 -0.947193793644724 0.34439012963872 -107.213230938699 128.476974825179 -0.83449373776574 0.404743280445364 DPP4 other 1 1 1 -0.947193793644724 -0.83449373776574 0.00663955203176857 -494.38806817211 381.693035496755 -1.29525042952038 0.196332098756073 -2151.5243298604 675.963418483522 -3.18290054022036 0.00162735948647098 SERPINB13 other 1 1 1 -1.29525042952038 -3.18290054022036 4.31180374516928e-09 75.1530986882216 12.1265236277541 6.19741493895399 2.20634185913788e-09 24.9216370934595 42.4328314522628 0.587319682437324 0.557492897091889 PDCD1LG2 other 4.48686297722315e-05 1 2.81440967551628e-05 6.19741493895399 0.587319682437324 0.00077553832622139 17.0810722487791 4.78091440844829 3.57276261181236 0.000418193619600809 4.77053419366858 10.3978669852772 0.45879930955295 0.646747398294996 ZNF433 other 1 1 1 3.57276261181236 0.45879930955295 0.375544264741459 12.8171043452383 23.1734434387824 0.553094510062667 0.580652988814692 66.3757470131668 47.7370742931844 1.390444387218 0.165530603757922 DNAH10 other 1 1 1 0.553094510062667 1.390444387218 0.303431620416096 276.997964300738 243.158799676559 1.13916487772267 0.255640328405563 -218.596857652614 453.160913607412 -0.482382418890592 0.629923697057522 SPTAN1 other 1 1 1 1.13916487772267 -0.482382418890592 0.846777011938875 -2.42575474386686 51.74994271895 -0.0468745396886901 0.962648525565886 -57.9025778522209 103.011197810818 -0.562099840432497 0.574523124671693 NMB other 1 1 1 -0.0468745396886901 -0.562099840432497 6.55938109007274e-06 141.108612016809 84.4141726413034 1.67162228333878 0.095774748438148 -377.904526625533 132.424897355672 -2.85372716288041 0.00466082732370262 PARVA other 0.0544756599530541 1 1 1.67162228333878 -2.85372716288041 0.945843208946976 -0.908449691991774 13.469782686816 -0.0674435299450635 0.946279092457366 6.91010342991864 25.9682875085574 0.26609777127743 0.790369278332814 KLHL14 other 1 1 1 -0.0674435299450635 0.26609777127743 5.08079925291675e-08 -113.905198376325 76.1050959633439 -1.49668293475627 0.135635222379567 -666.454585133777 122.059630586001 -5.46007375193722 1.07306937958116e-07 FAM114A1 other 0.000495530351136971 0.0016950203919864 1 -1.49668293475627 -5.46007375193722 5.77967416285674e-18 221.012776656363 35.9054668725852 6.15540740469 2.73334711265706e-09 -220.757979405678 62.273841386318 -3.54495522503899 0.000463503548105907 RPE essential 8.18459658202143e-14 1 3.47353751076459e-05 6.15540740469 -3.54495522503899 2.37776320670246e-10 21.7757493835597 3.88133751499014 5.61037253252504 4.96558119031454e-08 -12.0253914025133 8.64995636768417 -1.39022567182415 0.165596919181246 ZNF460 other 2.65738815981067e-06 1 0.000596763547452002 5.61037253252504 -1.39022567182415 2.10321077908468e-15 255.275585378097 56.7390041273226 4.49911994939595 1.01914647492629e-05 -531.522669560339 108.356032037185 -4.90533530591016 1.62313837472146e-06 PHF2 other 2.81073088516876e-11 0.0253209586456547 0.104584811256936 4.49911994939595 -4.90533530591016 6.61005274800069e-05 3325.83262214887 2362.25124194206 1.40790808492268 0.160300145229207 -8936.89151398342 3703.15786581176 -2.41331637424654 0.0164693873181096 PSAP other 0.500248791968692 1 1 1.40790808492268 -2.41331637424654 0.323685134351166 369.298722044729 356.973456209825 1.03452712133212 0.301825890518963 -1496.41231806887 1474.10722553739 -1.01513125513875 0.310962258681719 S100A10 other 1 1 1 1.03452712133212 -1.01513125513875 0.0653719034444896 -15.6873478956203 28.6184291615747 -0.548155449310381 0.584036410833213 -95.2826116756563 43.4748623633688 -2.19167138194185 0.0292542960753741 CFAP43 other 1 1 1 -0.548155449310381 -2.19167138194185 4.6382982710908e-18 60.2745957409673 6.976934106188 8.6391235496274 4.84052380592741e-16 -9.22937320347687 13.6609528914385 -0.675602447122195 0.49986495036815 LHFPL5 other 6.57803460806097e-14 1 7.17752869942916e-12 8.6391235496274 -0.675602447122195 9.8728629477923e-06 2208.64914360206 895.596165996822 2.46612170469017 0.0142733476476373 -3006.83262533669 1343.08011494464 -2.23875894809195 0.02597751906671 RPL37A essential 0.0809179847201057 1 1 2.46612170469017 -2.23875894809195 0.0023735485909751 39.5324454080841 15.7823784685946 2.50484712977514 0.0128356770540802 -65.9102679262815 43.3044638048691 -1.52202018302951 0.129165704434387 HOXC6 other 1 1 1 2.50484712977514 -1.52202018302951 3.2615195613451e-10 74.943641356637 11.4119028540535 6.56714680409475 2.65101273709914e-10 -34.5490326992524 43.5567810752628 -0.793195269401434 0.428365727739995 TXNRD3 other 3.61832980135625e-06 1 3.49376968622295e-06 6.56714680409475 -0.793195269401434 0.997730966732987 4.03926137838691 71.2842684491376 0.0566641345456043 0.954854810246229 7.71100042004427 125.602477617724 0.0613921044098591 0.951092528459345 CFD other 1 1 1 0.0566641345456043 0.0613921044098591 8.23593247951364e-14 486.865058421075 85.9295302068356 5.6658643105481 3.74547662680541e-08 -217.481389666358 119.309113723573 -1.82283970502236 0.0694335268604274 MCMBP essential 1.05279924885623e-09 1 0.000452153938387949 5.6658643105481 -1.82283970502236 9.57878401119994e-08 201.818818451678 62.3719787601412 3.23572896777568 0.00136455247021111 -249.658921084588 114.293512076822 -2.18436651869426 0.0297955679158507 EME2 other 0.00091841381099385 1 1 3.23572896777568 -2.18436651869426 0.200362367673591 2.85259297675387 3.61717978866668 0.788623497701604 0.431037019849131 -6.28963643855683 6.60089211016814 -0.952846423420276 0.341536186219549 KLHDC1 other 1 1 1 0.788623497701604 -0.952846423420276 3.16328255804403e-21 33.0528441274969 35.7802378231098 0.92377374043469 0.356422885654794 -408.968887357176 53.3462014855736 -7.66631692544733 3.14609311253698e-13 TAF13 other 4.69747459869538e-17 5.02368148209904e-09 1 0.92377374043469 -7.66631692544733 5.01420136504975e-48 115.246568899082 6.42330579702314 17.9419402626748 4.90866397583566e-48 4.7094086394266 41.7088404697161 0.112911521547716 0.910183989513822 ZNF780A other 7.98110431274968e-44 1 7.81459304953036e-44 17.9419402626748 0.112911521547716 1.61839306116852e-12 296.803495406677 59.7143145549828 4.97039106315775 1.20079200598122e-06 -213.009452722384 94.705826586657 -2.2491694587289 0.0253231228373221 ATAD3A other 1.97978023172745e-08 1 0.013239932657949 4.97039106315775 -2.2491694587289 1.93346927249533e-11 105.568657003646 22.1580736037841 4.76434273535482 3.09236956418339e-06 -102.072751525493 39.8512766391396 -2.56134207317322 0.0109685989270484 FAM118B other 2.26911953820052e-07 1 0.0330790772280697 4.76434273535482 -2.56134207317322 2.8837253640484e-13 36.9665263174281 4.71596131069781 7.83859830095983 1.05650194092863e-13 3.73295243625058 19.0655437287895 0.195795750142374 0.844917310324744 ZNF461 other 3.62224742978119e-09 1 1.51544638406803e-09 7.83859830095983 0.195795750142374 0.719372037688879 9.6636993208811 11.9289426628158 0.810105270352602 0.418595735546654 6.51294730718659 22.934340007857 0.283982329770786 0.776642383748588 CCDC180 other 1 1 1 0.810105270352602 0.283982329770786 4.15900823535644e-06 66.3486464198372 20.8963773977721 3.17512672923447 0.00167195280481294 -204.43059472552 68.3442040580075 -2.99119138986545 0.00303659636502566 SLC9A8 other 0.0352018457040569 1 1 3.17512672923447 -2.99119138986545 0.00470976440660835 51.7758692801189 52.2948350343318 0.990076156586551 0.323023330709709 -183.076160432627 81.2993157077038 -2.25187824570188 0.0251338043859372 OCLN other 1 1 1 0.990076156586551 -2.25187824570188 6.92992791231564e-08 14.1473743951412 2.39058535840169 5.91795408828234 9.81826588024153e-09 12.2698551028698 10.1367584778057 1.21043182884691 0.227167888345051 HIST4H4 other 0.000670193328400045 1 0.00012195268049848 5.91795408828234 1.21043182884691 8.28355625941854e-20 59.2074076612134 5.97557474706059 9.90823647387857 6.10481299340274e-20 -2.23679679009548 23.1980324201329 -0.0964218322306604 0.923257083353771 ZNF181 other 1.20799100931101e-15 1 9.34463724900157e-16 9.90823647387857 -0.0964218322306604 5.40257373677162e-07 32.695005600631 8.77815267701637 3.72458839617082 0.000238520471649762 -36.0347309303464 19.2339539683071 -1.87349574558216 0.0620882029069982 ZNF44 other 0.00491796287258321 1 1 3.72458839617082 -1.87349574558216 1.73876534850351e-18 706.218761880625 73.6879468464732 9.58391150932746 6.61038851931646e-19 179.800957158938 279.207274129059 0.643969458603101 0.520143916410369 GPAA1 other 2.48608669529032e-14 1 1.00550619767323e-14 9.58391150932746 0.643969458603101 0.0811366705979162 -55.8212482631987 25.8427617322509 -2.16003416513861 0.0316436717245692 -69.8106308205046 48.8835034381654 -1.42810203668832 0.154409674242397 ADAMTSL2 other 1 1 1 -2.16003416513861 -1.42810203668832 0.000565924621297919 41.4027113699762 16.2524505871514 2.54747498833854 0.011405455977357 -31.5410757573461 25.7283610381794 -1.22592635071239 0.221294563577869 SGTB other 1 1 1 2.54747498833854 -1.22592635071239 2.266862115065e-05 13.4005566835645 3.11389019740208 4.30347759042516 2.35351393011788e-05 -11.7072138352578 13.6434895757998 -0.85808060835283 0.391609024996482 ZNF790 other 0.180034189178462 1 0.234386452300439 4.30347759042516 -0.85808060835283 0.734463667669083 -39.5262754626326 62.2921534955869 -0.634530566766052 0.526265999896713 -164.108047311516 272.055323037556 -0.603215719064836 0.546866006120098 PRB3 other 1 1 1 -0.634530566766052 -0.603215719064836 0.0559161099396705 53.6634407359085 24.3016087792738 2.20822585135502 0.0280784980335267 -34.3384364695327 76.7742186259272 -0.447265202878096 0.655046207694887 FAM49A other 1 1 1 2.20822585135502 -0.447265202878096 2.025809813172e-06 889.73752877974 219.4614697041 4.05418559339538 6.57985135319917e-05 -1469.2698767081 679.731147810773 -2.16154560731874 0.0315288760209307 MYO1C other 0.0176022614666515 1 0.628770595311713 4.05418559339538 -2.16154560731874 1.13169743770595e-05 42.9320600538983 9.16635976204151 4.68365427153348 4.46935393005981e-06 5.96832937164449 24.6894661565163 0.24173586151312 0.809168334057719 NKIRAS1 other 0.0922220241986582 1 0.0471874387935715 4.68365427153348 0.24173586151312 0.94626835974733 -1.40196051551164 9.9874593138786 -0.14037208778047 0.888478590463293 -7.90889533154993 23.8607775882411 -0.331460083490638 0.740573562982155 UGT2B17 other 1 1 1 -0.14037208778047 -0.331460083490638 5.28827299064453e-06 26.4041104799897 60.5753575083669 0.435888644591866 0.663265816945752 -382.291876839768 104.278342224566 -3.66607167590461 0.000296543004798461 KIF13B other 0.0443157276616012 1 1 0.435888644591866 -3.66607167590461 2.08653117435436e-08 1034.56116767849 303.563666921109 3.40805333580107 0.000753697169841441 -802.07683940525 447.615278893569 -1.79188887695668 0.0742663104533546 ADH5 other 0.000208465329629744 1 1 3.40805333580107 -1.79188887695668 0.000682045504097607 288.444040279548 81.444359539999 3.54160855225201 0.000468043885016703 -8.51810936720221 141.783368285734 -0.0600783397248383 0.952137521218371 HIST1H2BK other 1 1 1 3.54160855225201 -0.0600783397248383 1.19429656923418e-13 165.41716524311 20.5544309218833 8.0477618607771 2.63313345557037e-14 16.4725531443545 97.2077139266798 0.169457262998481 0.865562943579862 TEAD4 other 1.51890637675203e-09 1 3.81225061697478e-10 8.0477618607771 0.169457262998481 3.51475039327649e-08 191.769549611652 77.9034400249094 2.46163134195787 0.0144680720651516 -389.005489956045 126.960096336972 -3.06399806852353 0.00240923502695386 SPG7 other 0.000346132618729868 1 1 2.46163134195787 -3.06399806852353 0.00639034489804552 7.01515537082592 2.36738908603476 2.96324563300911 0.00331456360745248 15.3067737344605 10.173133114186 1.50462729256102 0.133584482110846 HRNR other 1 1 1 2.96324563300911 1.50462729256102 0.511269334301182 16.1907375803763 17.0637778485434 0.948836636534058 0.343545957082701 -11.0860069020589 42.2400961339028 -0.262452217601869 0.793171484751594 ZNF677 other 1 1 1 0.948836636534058 -0.262452217601869 8.09838980623007e-07 1686.07278672637 376.183708748145 4.48204626494125 1.09491398481969e-05 -529.073499449384 717.014916931964 -0.737883532065465 0.461228426694779 ERO1A other 0.00726101630026588 1 0.11209729376584 4.48204626494125 -0.737883532065465 3.28405114793027e-20 30.8625024972616 4.23297120606163 7.29097860459489 3.359020214753e-12 -27.5879139426423 9.25664990099619 -2.98033459596147 0.00313973170798216 ZNF823 other 4.81244855217702e-16 1 4.67642794297913e-08 7.29097860459489 -2.98033459596147 0.00453547303440001 16.8079576069523 5.53009178658297 3.0393632249887 0.00260079102627146 -3.0830889058946 10.5058660081365 -0.29346356630732 0.769390808441827 ZNF311 other 1 1 1 3.0393632249887 -0.29346356630732 0.0531654173068587 27.6626270186245 13.5619092422583 2.0397295487297 0.0423469801156293 -16.8099475133615 34.5210446831264 -0.486947821760971 0.626688920795086 ZNF347 other 1 1 1 2.0397295487297 -0.486947821760971 0.0171364436342328 4.27265404752323 57.2027723728858 0.074693128851714 0.94051357666627 -218.626836400567 95.7573116308347 -2.28313465235345 0.0231911666889144 PLCG2 other 1 1 1 0.074693128851714 -2.28313465235345 0.000402164024321064 38.3130591956622 30.9992144355018 1.23593645495043 0.217548475236846 -146.752297032685 51.3882647521562 -2.8557550588732 0.00462445222537801 FCHSD1 other 1 1 1 1.23593645495043 -2.8557550588732 1.62216658260139e-06 59.1728316450471 14.2665440655585 4.14766402943364 4.49379835587264e-05 -43.1029667803366 32.5472760678898 -1.32431871381276 0.186508919091114 ZNF71 other 0.0142118014301708 1 0.436302882371675 4.14766402943364 -1.32431871381276 0.253434146874051 8.10905727513653 4.88853676417982 1.65879028149173 0.0983366724974137 0.349098219079971 32.0221354282397 0.010901778235942 0.991309983531784 AADACL2 other 1 1 1 1.65879028149173 0.010901778235942 0.660692995662827 1344.58166530681 1494.55430762457 0.899653935924132 0.369100222603297 -482.720417916139 5092.77133676126 -0.0947854097496402 0.924555064607039 S100A6 other 1 1 1 0.899653935924132 -0.0947854097496402 3.33051299227131e-08 1081.49252577078 332.479098712084 3.25281357522964 0.00128747818281204 -2040.46657990582 616.828702938049 -3.30799551023933 0.00106675285052745 RPL12 essential 0.00032862171694741 1 1 3.25281357522964 -3.30799551023933 0.692307369986859 3.89430983019662 8.82659716253531 0.441201717772519 0.659420063789571 -20.2852082638219 29.0440821465381 -0.698428277453408 0.485510506465634 DNM3 other 1 1 1 0.441201717772519 -0.698428277453408 9.68256628112659e-12 187.018067950461 52.7209037807798 3.547322874587 0.000458182982609727 -416.05321271016 104.950033816948 -3.96429803382278 9.41526479978988e-05 ZNF121 other 1.14864283793005e-07 1 1 3.547322874587 -3.96429803382278 0.000473904683784024 602.419424261212 154.884611272975 3.88947242279275 0.000126460103147669 -295.396608769559 522.172058148263 -0.565707421835439 0.572060777067692 MPZL1 other 1 1 1 3.88947242279275 -0.565707421835439 3.78321816081328e-10 108.133221024259 34.3479462639477 3.14817136935367 0.00182724492079055 -251.125196972839 64.2110542168907 -3.91093402896943 0.000116379521234519 VPS13A other 4.18537425130773e-06 1 1 3.14817136935367 -3.91093402896943 2.84193855733559e-09 265.034757433869 75.2207166175089 3.52342771183035 0.000502502472517253 -317.748271428226 116.251830674393 -2.73327542099702 0.00669787806000882 MBP other 2.99398227015304e-05 1 1 3.52342771183035 -2.73327542099702 9.34062423806189e-05 75.9632183934373 20.3077425422321 3.74060377392828 0.000224207708421143 -29.8184952489807 37.829089894962 -0.788242469797084 0.43124639173255 ELOVL2 other 0.694942443311805 1 1 3.74060377392828 -0.788242469797084 0.19204010054978 13.0628425022211 18.3818378573274 0.710638544611791 0.477921637087467 -47.4101107666757 35.8001262543123 -1.32430009966697 0.186523317269937 GOLGA6L9 other 1 1 1 0.710638544611791 -1.32430009966697 1.49042517673897e-05 4.24914024975986 0.890277776169462 4.7728252501622 3.02269588450169e-06 -2.21972814601345 6.0457073290678 -0.367157724513224 0.713797750988237 LEKR1 other 0.12030712026637 1 0.0323640048353596 4.7728252501622 -0.367157724513224 8.3380210186742e-11 30.967597090667 43.7475815464122 0.707869920942101 0.479636641122138 -376.686619622903 66.5287390694309 -5.6620135131343 3.82139001260135e-08 C1orf122 other 9.52118620122407e-07 0.000605575675296936 1 0.707869920942101 -5.6620135131343 3.92085913317839e-09 89.8787845107362 34.3646581019404 2.61544241889784 0.00940868890714525 -172.763128528876 49.8802488662656 -3.46355787021178 0.000619070574798288 SNHG12 other 4.08984816181838e-05 1 1 2.61544241889784 -3.46355787021178 0.519622968676421 -6.89671167902877 37.4793591255373 -0.184013596815468 0.854146221997673 -68.0173420260955 62.7987258959192 -1.08310066893436 0.279767160237952 PCDH20 other 1 1 1 -0.184013596815468 -1.08310066893436 0.225300244592169 8.10373384900167 21.4902746925528 0.37708842557559 0.706400846691266 -82.9596896803558 58.5188311279776 -1.41765800993064 0.157430970985487 KEL other 1 1 1 0.37708842557559 -1.41765800993064 1.52299417765923e-18 176.90510928661 27.3407866473107 6.47037378875162 4.57753644165503e-10 -207.906753864923 53.7077703310331 -3.87107401002629 0.000135962266395966 NOL8 essential 2.17864317114153e-14 1 5.98467114381979e-06 6.47037378875162 -3.87107401002629 8.48670087552897e-05 57.8570067245431 29.5257035417079 1.95954709911703 0.0511048962300269 -237.613441123262 75.7677442520902 -3.1360764856967 0.00190669322956005 IRAK4 other 0.634296023437035 1 1 1.95954709911703 -3.1360764856967 0.0190959866608227 15.7087946872699 5.68021429968535 2.76552852735505 0.00607211555313403 21.4407362556952 11.3994814082533 1.8808518991199 0.0610602964996437 CCDC151 other 1 1 1 2.76552852735505 1.8808518991199 6.93194565447188e-06 244.461864210755 57.4788931315484 4.25307188242596 2.90587974209517e-05 -177.344404153129 131.72257067917 -1.34634788281712 0.179315377126196 MRPL42 other 0.0575074211494987 1 0.28733338889837 4.25307188242596 -1.34634788281712 4.2668656542822e-08 198.787042401896 36.5501879853247 5.43874199721522 1.19230218945161e-07 21.950822731905 58.8786040983165 0.37281493112933 0.709575474495865 ENTPD7 other 0.000418323508745827 1 0.00140405505829822 5.43874199721522 0.37281493112933 0.255319865828653 202.631578947368 122.775796853117 1.65041957894834 0.110031676797261 119.842105263158 141.930288748287 0.844373011004704 0.405617899184403 FCGR1B other 1 1 1 1.65041957894834 0.844373011004704 1.88443305056174e-06 87.4598252731127 21.6868734123285 4.0328462111737 7.16968688908468e-05 -149.117827295679 72.0779303007813 -2.06884169222688 0.0395091409036704 ZNF335 essential 0.0164284873347973 1 0.683056069923097 4.0328462111737 -2.06884169222688 1.16557928616864e-06 67.8738222791325 13.3632640489601 5.07913501001382 7.36441251138875e-07 -5.03310835795994 40.2120604185504 -0.125164149898623 0.900492994629247 ZNF273 other 0.0103305292133127 1 0.00823856827649059 5.07913501001382 -0.125164149898623 0.000991960835739222 110.252324225968 39.8176633639784 2.76893004037272 0.00601521283005434 -156.969306990664 82.2198736441929 -1.90914069839063 0.057307876218009 ZNF84 other 1 1 1 2.76893004037272 -1.90914069839063 7.35426374082044e-28 250.210119233912 31.8485504620849 7.85624826259463 1.09491724838338e-13 -167.727384105707 58.4546025016503 -2.86936146903012 0.00445631896130483 MAK16 essential 1.14270550004868e-23 1 1.57011133418177e-09 7.85624826259463 -2.86936146903012 0.256133977221136 11.0734034352039 11.566369024881 0.957379399825764 0.339222842942036 -22.2792018483607 26.3846073893405 -0.844401492112465 0.39918443547775 ZNF667 other 1 1 1 0.957379399825764 -0.844401492112465 0.0134372498669573 193.412698988663 76.6918754559985 2.5219450931231 0.0122400113189086 -351.661982344373 307.814310321557 -1.14244845204569 0.254268621905871 SIRPA other 1 1 1 2.5219450931231 -1.14244845204569 0.835694840319054 -2.39158790494336 8.89437477234411 -0.268887692070239 0.788219947505058 -8.53288035597907 14.2453150434281 -0.5989955525705 0.549674395632006 DSCR8 other 1 1 1 -0.268887692070239 -0.5989955525705 3.31505765788597e-13 316.769764615393 52.905346118643 5.98748118772383 6.74282059934326e-09 -182.840573753648 89.1116965546282 -2.0518134074752 0.0411486649451478 GRK6 other 4.15376724533112e-09 1 8.43189715947875e-05 5.98748118772383 -2.0518134074752 4.21764747075558e-07 101.684046610411 19.2909996085045 5.27106156622299 2.76586475561013e-07 3.0992626488689 51.6330278615128 0.0600248092593285 0.952179953239358 PRIM1 essential 0.00387475273138315 1 0.0031846166796095 5.27106156622299 0.0600248092593285 1.35543773637634e-16 389.252903802951 55.8975664238175 6.9636824768295 2.48839611247638e-11 -29.8593384225197 79.0678304727765 -0.377642060544465 0.705991023219498 MARCH5 other 1.86426906261202e-12 1 3.38421871296787e-07 6.9636824768295 -0.377642060544465 0.0325741839585574 56.9931975352846 55.0734138001085 1.03485862964922 0.301674829150876 -177.648077659902 110.074662795507 -1.61388709398029 0.107737533142584 NPIPB13 other 1 1 1 1.03485862964922 -1.61388709398029 2.90764269166519e-05 5089.60258422783 1172.93280040592 4.33921072244416 2.02027385750987e-05 441.292551343298 3146.6012137543 0.140244194089273 0.888571233964666 AKR1B10 other 0.228133645588051 1 0.202128399443863 4.33921072244416 0.140244194089273 0.739604558878807 9.65734226844261 12.571438437011 0.768197077592241 0.443038982649538 3.26681867474905 43.8892409262561 0.0744332461852793 0.940720568150162 SULT1C4 other 1 1 1 0.768197077592241 0.0744332461852793 3.32734289546339e-10 62.5243087275955 11.7404063672171 5.32556597889004 2.13799257822965e-07 -47.5561493971872 25.7848597428234 -1.84434392397357 0.066240752715111 ZBTB14 other 3.68902506820026e-06 1 0.0024783609966838 5.32556597889004 -1.84434392397357 1.67818735637713e-17 293.660342190388 40.5620701360405 7.23977699376498 4.6128578230015e-12 -339.651789520315 100.550197192038 -3.37793260486227 0.000837094937132266 CD2AP other 2.35600722961785e-13 1 6.39711122893848e-08 7.23977699376498 -3.37793260486227 0.000222278790539038 81.9851992185187 23.9075584186166 3.42925855426029 0.000699830776183643 -68.7736050537545 63.3092085181217 -1.08631282341918 0.278309496659073 SFI1 other 1 1 1 3.42925855426029 -1.08631282341918 0.000822009069429711 26.6808281446517 11.9177190360045 2.23875290767022 0.0259869109857115 -32.6410790905187 22.7044502105944 -1.43765115595213 0.151690996568449 TMPRSS11F other 1 1 1 2.23875290767022 -1.43765115595213 0.00787971096442249 29.3153318843003 11.0289885086178 2.65802542648349 0.00832361301906536 -14.2551303528713 25.7437980925804 -0.553730661715363 0.580216423027717 ZNF649 other 1 1 1 2.65802542648349 -0.553730661715363 3.04138952376366e-06 16.7058715599714 9.2451181048897 1.80699385020682 0.0719511747266115 -49.4575032147501 15.6902543130786 -3.1521160988146 0.00181628230803736 ZNF248 other 0.0260038804281793 1 1 1.80699385020682 -3.1521160988146 0.116315386868926 21.0706573481045 11.2052600929203 1.88042554776728 0.0611185667260685 2.64408970919157 18.3210385293111 0.144319859649953 0.885354768681042 CHSY3 other 1 1 1 1.88042554776728 0.144319859649953 0.372510245610731 -17.5930073029179 41.7650560612663 -0.421237488035697 0.673919305647335 84.9663974629159 78.6211656819211 1.08070640680483 0.28079927365881 TOR4A other 1 1 1 -0.421237488035697 1.08070640680483 3.5246714753388e-11 267.256674933076 59.9688383231426 4.45659249713928 1.21818630463952e-05 -358.169350352868 116.126119962413 -3.0843134212079 0.00225027837537289 LPAR1 other 4.08932384568808e-07 1 0.124242821210184 4.45659249713928 -3.0843134212079 0.551529752937798 1.10113645402484 23.3551423620524 0.0471474948409639 0.962430399565935 57.3433731705377 55.4776805331071 1.03362960779006 0.302230863716459 MB other 1 1 1 0.0471474948409639 1.03362960779006 7.13131006104784e-07 119.826108317202 25.5525589902897 4.68939758099132 4.36207206911135e-06 -87.7869680897103 65.06522827263 -1.34921478676558 0.178402514400043 HIBCH other 0.00642673662701631 1 0.0461158259146451 4.68939758099132 -1.34921478676558 7.26866427489309e-17 193.894862756622 25.335109385921 7.6532080364481 3.55218658953699e-13 -118.737298812153 60.9340031859409 -1.94862133790594 0.0523841588408468 ZNF544 other 1.00678268871544e-12 1 5.05724804752381e-09 7.6532080364481 -1.94862133790594 0.00770825891825965 37.9451813842835 13.2584917779785 2.8619530803125 0.00453760479177651 6.77486292482701 24.054684120358 0.281644227416534 0.778430477669876 TMEM229B other 1 1 1 2.8619530803125 0.281644227416534 2.61612543851211e-06 482.446305706947 98.5049463508216 4.89768609170887 1.66927755536634e-06 -132.400994679872 318.977006644156 -0.415080058819337 0.678411720110481 SOWAHC other 0.022477749767696 1 0.0182218337943789 4.89768609170887 -0.415080058819337 1.29133724292423e-15 505.439907732569 82.6673955061981 6.11413852629085 3.41671948880144e-09 -344.679648902491 147.246641323817 -2.34083199320308 0.0199743292704872 ZNF770 other 1.73452418469583e-11 1 4.32795857646478e-05 6.11413852629085 -2.34083199320308 0.147432327928109 3.80538450276325 2.61833585571088 1.45335996314731 0.147311488911879 -6.4308383281437 8.41543460119315 -0.764171861929973 0.445447283793405 NPIPB6 other 1 1 1 1.45335996314731 -0.764171861929973 4.25903115401053e-10 99.1191307601166 51.2013238873392 1.93587046651788 0.053919671402939 -347.153551162936 79.2006743701237 -4.38321458654006 1.67208419706173e-05 MIER1 other 4.69643365352741e-06 0.256046253096062 1 1.93587046651788 -4.38321458654006 3.90924516361364e-12 299.845309305534 72.2745344131728 4.1486992858564 4.5128170664862e-05 -342.298557681888 126.064392097948 -2.7152675865516 0.00705905547112544 MAN1A2 other 4.70868579957263e-08 1 0.438014024473151 4.1486992858564 -2.7152675865516 0.000647616390647127 46.022067057672 43.003614315663 1.07019067559886 0.28549279735573 -195.858711414748 77.2936633027851 -2.53395560574615 0.011846251208972 SVIP other 1 1 1 1.07019067559886 -2.53395560574615 4.58587942491882e-05 56.7773598528073 15.9979121641586 3.54904810516525 0.00045896383980563 -108.39925161671 59.8422962666227 -1.81141530956208 0.0712349241620559 ZNF251 other 0.352424833805011 1 1 3.54904810516525 -1.81141530956208 8.83035170875682e-18 336.990883247168 38.8800411362901 8.66745181842478 3.98352273374184e-16 -306.459374813882 140.051336572375 -2.18819314627183 0.0295031711996117 DDRGK1 other 1.24649244720811e-13 1 5.91234444141964e-12 8.66745181842478 -2.18819314627183 3.39500421751957e-21 1146.20017730496 122.112314299333 9.38644217728354 3.06316131839371e-18 -145.66755319149 228.916973616156 -0.636333561860478 0.525112435574057 TFDP1 other 5.03886525964254e-17 1 4.63578833925705e-14 9.38644217728354 -0.636333561860478 1.26882098138824e-13 55.7183957990674 7.12849373235567 7.81629301940268 1.24579023356842e-13 -19.0708485927982 35.0036875097583 -0.54482398711512 0.586327650980222 ZNF607 other 1.61229082105004e-09 1 1.78509282568019e-09 7.81629301940268 -0.54482398711512 0.168022925471327 -178.381596766021 119.090508166003 -1.4978657788358 0.13534940050953 -883.159182193804 610.730025773744 -1.4460713325416 0.149330005464502 BPIFA1 other 1 1 1 -1.4978657788358 -1.4460713325416 1.2578249328954e-07 78.0031901248642 14.5819172183922 5.34930962483305 1.88942341906212e-07 -30.6107092350749 48.3653982236335 -0.632905142092205 0.527333243507807 ZNF334 other 0.00119669464115668 1 0.00219702155168543 5.34930962483305 -0.632905142092205 0.00556334971800027 -26.5880156622349 109.922189791529 -0.241880331102028 0.809055823371365 -453.398601307783 168.286649495765 -2.69420422039595 0.00749618747402853 HSD17B11 other 1 1 1 -0.241880331102028 -2.69420422039595 5.46218311464054e-17 416.778302386363 58.4884001445751 7.12582839257263 9.50139362854563e-12 -223.906014588066 111.102641878311 -2.01530774428665 0.0448669596844686 SZT2 other 7.58533369130132e-13 1 1.30824688871445e-07 7.12582839257263 -2.01530774428665 0.599573810103352 -6.1774138234667 7.2382398594213 -0.853441436515284 0.394168256403223 -18.632627978756 25.2700480270342 -0.73734042605786 0.461553265189872 SULT1C2 other 1 1 1 -0.853441436515284 -0.73734042605786 1.214001574696e-07 75.6857309445563 14.6159317364034 5.17830353271618 4.361478014916e-07 1.12509275946133 28.821887158399 0.0390360545538903 0.968890278761241 RPS6KL1 other 0.00115633649989794 1 0.00495594746834905 5.17830353271618 0.0390360545538903 0.00875379173503019 28.8829923273657 11.6118568710479 2.48737068051367 0.0134731775819538 74.2774936061384 36.3105620489708 2.04561674110037 0.0417630925934657 CACNA1E other 1 1 1 2.48737068051367 2.04561674110037 1.77612696782201e-11 278.038807826931 49.4529996798968 5.62228397926601 4.65390845196084e-08 -321.232509593891 118.111059743815 -2.71974961778052 0.00695221240805773 QRICH1 other 2.08783725067477e-07 1 0.000560097882193487 5.62228397926601 -2.71974961778052 1.58031642830421e-06 411.381738378564 81.5092147146838 5.04705805127152 8.23882020688706e-07 -68.8013327801622 180.616131020723 -0.380925736761951 0.703556797235905 DDX42 essential 0.0138593750762279 1 0.00918793229472045 5.04705805127152 -0.380925736761951 1.39663031482324e-17 755.497881306694 94.2429511312781 8.01649218575832 3.66127997680689e-14 -252.778869617088 212.933120800785 -1.18712799900013 0.23625646877186 RPL23A essential 1.96450020083036e-13 1 5.28688828650915e-10 8.01649218575832 -1.18712799900013 0.000893731086025839 20.601971999782 21.1774796431014 0.972824545081933 0.331504837208214 -74.7173089284743 33.1421158100488 -2.25445198962885 0.0249634868728265 SLC29A3 other 1 1 1 0.972824545081933 -2.25445198962885 9.58979912743996e-20 168.371447030321 22.1825915579685 7.5902514181143 5.25541731586123e-13 -111.831492548271 42.2805365394519 -2.64498754513017 0.0086498334043624 STYX other 1.3968501409029e-15 1 7.45007958696489e-09 7.5902514181143 -2.64498754513017 3.45501343352192e-08 544.887175930163 123.979382901362 4.39498215895845 1.58972037493597e-05 -370.671260083708 246.443563544872 -1.50408172464288 0.133720550229467 UBL5 essential 0.00034045702373925 1 0.160577655072283 4.39498215895845 -1.50408172464288 4.55417083226685e-10 254.509716927988 39.9346035717234 6.37316247476661 7.96604866173413e-10 -65.7790370275654 87.8489035170191 -0.748774707413645 0.454644797987365 HELZ other 5.01596375465871e-06 1 1.03279820899383e-05 6.37316247476661 -0.748774707413645 0.243886065992734 127.045014996936 86.3510681707074 1.47126164954648 0.142389206163649 -64.4019286382354 181.039587082051 -0.355733956734264 0.722318616438329 TMEM116 other 1 1 1 1.47126164954648 -0.355733956734264 0.00314431120013611 324.307279151945 98.1104249414064 3.30553332477796 0.00107579947173317 -42.76391048292 269.899748128878 -0.158443684291621 0.874225197655351 CARD11 og 1 1 1 3.30553332477796 -0.158443684291621 7.38982762815745e-12 24.5183741153994 5.47415487527664 4.47893321873914 1.11455885042517e-05 -19.1184536939347 8.75819046562258 -2.18292280454256 0.0299159264422546 ZNF485 other 8.80793555000086e-08 1 0.11400822480999 4.47893321873914 -2.18292280454256 0.371654773830955 17.789260933355 131.765143690118 0.135007335287331 0.892705560061913 393.797249136743 295.122271525258 1.33435286703884 0.183200152350771 PEG3 other 1 1 1 0.135007335287331 1.33435286703884 8.55727591227119e-32 337.513038883277 32.0231678382785 10.5396518104569 5.57203013090439e-22 -140.967986223132 63.1169659148655 -2.23344047325206 0.0263392948922779 SDAD1 essential 1.34511820064991e-27 1 8.60655774019492e-18 10.5396518104569 -2.23344047325206 5.63309781247719e-09 221.96133494161 38.7898535899074 5.7221493354479 2.77171920050377e-08 -37.4117870899884 70.3482850770716 -0.531808089550457 0.59529299259432 ZKSCAN8 other 5.82405982832017e-05 1 0.000336763882861207 5.7221493354479 -0.531808089550457 0.0190955820633546 17.3506984387838 14.2242510897126 1.21979697415018 0.223598443324837 -63.985477204253 30.8307272879991 -2.07538007801585 0.0388911177692459 FAM109A other 1 1 1 1.21979697415018 -2.07538007801585 8.53603911852957e-10 61.9231328815132 10.6637249527974 5.80689516614631 1.77146070031789e-08 -1.55576154779225 19.1687096775611 -0.0811615165528555 0.935373191010982 HYLS1 other 9.26074883969273e-06 1 0.000217375942536008 5.80689516614631 -0.0811615165528555 0.0963532633198243 2.96948163647205 1.61179679501713 1.84234243773917 0.0665296676041811 -0.57269729347532 3.531634331537 -0.162162115245402 0.871300386565169 ZNF442 other 1 1 1 1.84234243773917 -0.162162115245402 0.00211532241467103 30.6523775049144 10.2954944951727 2.97726131749054 0.00317036088776965 -16.5572881579947 25.4491488844414 -0.65060282499731 0.515852087751919 ZNF813 other 1 1 1 2.97726131749054 -0.65060282499731 0.0661488443436453 14.616064244892 10.7290941160472 1.36228316079652 0.174235534625722 -40.0706149877048 29.4390144509551 -1.36113982533151 0.174596078801985 HOXC4 other 1 1 1 1.36228316079652 -1.36113982533151 1.8220386273634e-06 468.407860855511 118.644152422499 3.94800629690945 0.000100949336451537 -393.932735198144 253.533879493118 -1.55376763052623 0.121428803838776 PIM3 other 0.0159027531396277 1 0.946702877242514 3.94800629690945 -1.55376763052623 2.98750048501674e-15 614.090152866456 83.3475006717928 7.36782924403013 2.11528317507234e-12 -129.669200549009 186.175341954879 -0.696489659626544 0.486721392336677 ASNA1 essential 3.97516814536327e-11 1 2.95801199202116e-08 7.36782924403013 -0.696489659626544 0.0018901935063884 1080.88526280114 361.645302438708 2.98879939961152 0.00306470771619279 -843.658516677496 1091.84068681594 -0.772693788448022 0.440394845395242 ASPH other 1 1 1 2.98879939961152 -0.772693788448022 4.35249485954266e-08 208.394972141692 36.2620866495873 5.74691065507295 2.49239322569413e-08 426.960260514405 213.566739359882 1.99918892704979 0.0466089864980921 SPRED2 other 0.000426326871492203 1 0.000303473799160517 5.74691065507295 1.99918892704979 1.96525288579599e-12 161.020319358988 55.5678911918064 2.89772233398575 0.00406478427710043 -474.007418150762 102.489001819692 -4.62495887104726 5.79954193596823e-06 WWP2 other 2.39564326778531e-08 0.0896203215365171 1 2.89772233398575 -4.62495887104726 8.66987168757143e-07 458.125677606735 87.2770794452159 5.24909495733415 3.0976386516618e-07 689.540726029712 438.326145558698 1.57312250938353 0.116861495620961 GFPT1 other 0.00775693419887016 1 0.00355577940824259 5.24909495733415 1.57312250938353 1.14288397685913e-11 204.59373045806 30.7873521323354 6.6453824797482 1.64529146427321e-10 -38.9089009190317 77.2094386975353 -0.503939694102112 0.614711677932408 UVRAG other 1.35260318661278e-07 1 2.18576971028696e-06 6.6453824797482 -0.503939694102112 5.2142261657146e-05 64.685099365991 19.9538498545192 3.24173529607575 0.00133775667237538 -98.7087396582608 41.2028952768223 -2.39567484263143 0.0172735693640825 ZNF26 other 0.398731874892195 1 1 3.24173529607575 -2.39567484263143 0.00361234269950774 150.104949729574 44.7487218967827 3.35439635741564 0.000908523668695879 132.64009358946 156.427392021855 0.847933931999125 0.397220299596922 ITSN2 other 1 1 1 3.35439635741564 0.847933931999125 0.12049672216925 -2.41539234192889 1.32701739379974 -1.82016630167351 0.0698326453319445 -4.69432930645892 4.26671880526223 -1.10021998653141 0.272209039331926 NTRK1 other 1 1 1 -1.82016630167351 -1.10021998653141 4.32788526756292e-08 247.90271063431 139.062350216491 1.78267309770313 0.0757547726425717 -690.58884938079 194.718821162522 -3.54659526622951 0.000459393596130937 MGEA5 other 0.000424046198515814 1 1 1.78267309770313 -3.54659526622951 0.00202908173812313 127.131584567371 40.9515000812042 3.10444267768645 0.00210756891000264 32.1556537608413 73.5632984308577 0.437115442710396 0.662374460601771 MT1F other 1 1 1 3.10444267768645 0.437115442710396 1.24401383401468e-08 177.501885464326 37.5922751511361 4.72176490384521 3.7610664509521e-06 -225.710996027955 105.769081527505 -2.1339978826351 0.0337440564414497 TCAF1 other 0.000125990756972005 1 0.0399538089084641 4.72176490384521 -2.1339978826351 0.616398118922476 -2.22484980594396 3.48974493538684 -0.637539375265926 0.524315837425974 2.7372210365352 7.61370018201306 0.359512585352617 0.71949372415073 ZNF69 other 1 1 1 -0.637539375265926 0.359512585352617 0.0110646833370617 3348.01053911633 1174.40154665634 2.85082265827094 0.00469339862986938 -186.814636682475 2532.82320148004 -0.073757472125694 0.94125738007579 TXNRD1 essential 1 1 1 2.85082265827094 -0.073757472125694 2.16145978921377e-06 127.60802330899 59.2528270473268 2.1536191548644 0.0321620180949216 -400.082334230679 111.541244565226 -3.58685556889875 0.000397707624969145 NRARP other 0.0187268876137481 1 1 2.1536191548644 -3.58685556889875 0.00370866620443822 10.6048537661942 4.6111414575635 2.29983266915384 0.0222123525873831 -13.9890276321744 10.5186992316092 -1.32991991919843 0.184654702111142 ZNF583 other 1 1 1 2.29983266915384 -1.32991991919843 0.000409333681294442 5.51323864028132 1.97990822969135 2.78459302183959 0.00573863912402917 -5.44364384380245 3.87828703089943 -1.40362067078361 0.161580904094375 KRTAP4-1 other 1 1 1 2.78459302183959 -1.40362067078361 6.57339179419539e-07 30.1322056233109 5.57221914576829 5.40757727488054 1.40695617529892e-07 10.3126811670762 24.4146418177458 0.422397397596897 0.673071148093103 ZNF568 other 0.00594103150359379 1 0.00164951541992045 5.40757727488054 0.422397397596897 9.62144141822032e-13 111.790343064196 17.1753747566565 6.50875713910523 3.65290465708063e-10 -63.5197287770041 39.6709647490334 -1.6011642060848 0.11050556967075 ZNF480 other 1.18680479893748e-08 1 4.79261091008979e-06 6.50875713910523 -1.6011642060848 1.02514978763231e-08 113.335984684132 31.2694926150323 3.62449068424115 0.000345933383640874 -253.260869379734 75.8731273100539 -3.33795216249344 0.000962663641667566 ZNF587 other 0.000104378556527664 1 1 3.62449068424115 -3.33795216249344 0.517555024129238 -11.3546984228373 132.223435569678 -0.0858750823854803 0.931630322164403 -381.094138540305 368.480990386005 -1.03423011901126 0.30196793877242 TPM2 other 1 1 1 -0.0858750823854803 -1.03423011901126 0.000377436047109603 13.4334557543205 3.73390092383355 3.5977001072992 0.000381277586462413 -12.9595438162445 10.1845782173142 -1.27246740510204 0.204293769140003 FLVCR1-AS1 other 1 1 1 3.5977001072992 -1.27246740510204 0.02450309364694 141.415999381667 53.4927781919192 2.6436465661645 0.00868510230944132 192.046398206832 124.319366231223 1.54478263547163 0.123578826257487 SH3BGRL2 other 1 1 1 2.6436465661645 1.54478263547163 0.00702823173418935 17.2593795663259 9.26635291866634 1.8625860376587 0.0636025342882162 -40.4197535285434 23.5543856589363 -1.71601815958246 0.0873015365608804 ZNF808 other 1 1 1 1.8625860376587 -1.71601815958246 0.396930841416604 -7.99147117117742 13.6617280682824 -0.584953172192814 0.559102583480014 -57.5734894995272 46.2590902777945 -1.24458758600283 0.214439635571114 ANKRD35 other 1 1 1 -0.584953172192814 -1.24458758600283 0.335665869574319 -5.27295279251513 3.75447181626067 -1.4044459648566 0.161331163356793 -1.06979672392646 9.57928651832498 -0.111678121526062 0.911161297801419 B3GNT6 other 1 1 1 -1.4044459648566 -0.111678121526062 4.48855739955986e-18 310.971832050386 77.0169881191949 4.03770440320404 7.03113847614784e-05 -565.181119664098 111.936904990137 -5.04910440139376 8.15858823698502e-07 YTHDF2 other 6.36791638275557e-14 0.012788587061474 0.670489365085458 4.03770440320404 -5.04910440139376 0.000280148376946519 23.0827579839758 7.15874575713669 3.22441371255072 0.00141752999050457 -11.719515181195 13.3862547279942 -0.875488732235637 0.382086204117662 NBR2 other 1 1 1 3.22441371255072 -0.875488732235637 2.45966818684411e-17 139.450747934847 21.0401624127093 6.62783609743489 1.82267512540043e-10 -44.77986997621 30.6077469080599 -1.46302405435854 0.144615353423629 TMA16 essential 3.44304352794439e-13 1 2.41704948379351e-06 6.62783609743489 -1.46302405435854 0.550431117841226 -695.914171825544 683.366564010071 -1.01836145997814 0.309411146595709 -98.7831966078308 1254.94946094897 -0.0787148803053252 0.937317286135889 HLA-DRB5 other 1 1 1 -1.01836145997814 -0.0787148803053252 0.0159700500412715 -25.0234733693579 12.6997639122589 -1.97038886252076 0.0498192440102192 -68.1404897011302 24.3850911100696 -2.79435042475573 0.00557449038220481 ATL1 other 1 1 1 -1.97038886252076 -2.79435042475573 0.00508767286921113 4.61893049491316 6.42502066780132 0.718897375390667 0.472859824385561 -22.1759294354828 10.554133931487 -2.10116051013181 0.0366046881221128 CNGA1 other 1 1 1 0.718897375390667 -2.10116051013181 0.350377375271694 42.3585571013863 92.1184970280727 0.459826836823854 0.646010566537595 -277.497543767552 225.954663017625 -1.2281116046094 0.220474572825714 MAFK other 1 1 1 0.459826836823854 -1.2281116046094 0.200942486445966 2.75090703537177 4.46751637782459 0.615757571483442 0.538571334290668 -8.79666640677113 7.78844324455246 -1.12945117921015 0.259706293572414 C1orf228 other 1 1 1 0.615757571483442 -1.12945117921015 0.100410692367328 53.7889294272576 24.9808659475231 2.15320515871032 0.0321915349203252 52.933653202651 53.4552438092723 0.990242480073942 0.322945490887605 ZNF43 other 1 1 1 2.15320515871032 0.990242480073942 8.38646541226856e-10 384.578485158412 57.5058455652799 6.68764160196277 1.27739418637554e-10 158.436339880314 215.093193638746 0.736593925637703 0.46200182753388 GPN1 essential 9.10350820501752e-06 1 1.70238323218268e-06 6.68764160196277 0.736593925637703 0.867091355465081 -4.80182789097528 20.8041916906639 -0.230810596363142 0.817635461538723 13.8618656534884 37.8704230660425 0.366034084945779 0.71462416758919 PLN other 1 1 1 -0.230810596363142 0.366034084945779 0.000126015330139205 160.060491051039 42.743353361726 3.74468726626309 0.000220455380597788 -36.6161362859966 84.4337404426772 -0.433667110967986 0.664873937771081 C2CD4A other 0.922180185958699 1 1 3.74468726626309 -0.433667110967986 4.49444724292741e-05 71.4857925466878 20.5899045130749 3.47188557874531 0.000601959981819777 -78.1350736683655 52.5743474234173 -1.48618247296709 0.138401921939087 ZNF28 other 0.345667937453547 1 1 3.47188557874531 -1.48618247296709 0.663556747794676 24.4032760179189 79.3908669664295 0.30738140229956 0.758789165033792 -90.1380979712984 143.962308704097 -0.626122898296737 0.531761332194937 ITGBL1 other 1 1 1 0.30738140229956 -0.626122898296737 4.27101933425097e-16 304.305515135629 38.1579923307118 7.97488275845965 4.69429277941836e-14 87.7954377041149 53.3045624228397 1.64705296720524 0.100741432538009 ZNF511 other 5.80687788684762e-12 1 6.76729247080951e-10 7.97488275845965 1.64705296720524 5.25571580125641e-06 104.692324512652 22.5155542077957 4.64977781787861 5.19725170336278e-06 23.4060752799297 48.111270194501 0.486498801326699 0.627006751729733 ZNF627 other 0.0440586655619325 1 0.0545867346404193 4.64977781787861 0.486498801326699 0.000504714595513089 15.7470267984564 5.99484763339396 2.62676013827916 0.00910905805516234 -12.2036841270681 9.69129151594896 -1.25924229056411 0.209022378622715 KCNRG other 1 1 1 2.62676013827916 -1.25924229056411 1.59376217087353e-16 201.69425055241 29.0989460342077 6.93132494610991 3.00363083076445e-11 -97.3280799566853 54.699336100045 -1.77932835928159 0.0762984387207637 WDHD1 essential 2.18887296547771e-12 1 4.07532631118121e-07 6.93132494610991 -1.77932835928159 3.98617837056499e-10 65.6024082102697 10.212687877201 6.42361824811287 6.01008803241054e-10 -50.1815911223512 46.3659882478137 -1.08229314242466 0.28009151581611 ZNF789 other 4.40592295298548e-06 1 7.82573562700177e-06 6.42361824811287 -1.08229314242466 3.86497851405313e-05 524.47837276719 471.055087977322 1.11341196847966 0.266510901273849 -4513.25913931173 1205.25856793748 -3.7446397473325 0.00022033927120797 CTNND1 other 0.299342585913415 1 1 1.11341196847966 -3.7446397473325 6.7807536619937e-12 1452.46172877266 246.263842052096 5.89799020704549 1.08502189496911e-08 -923.12052395758 474.155989163286 -1.94687095608885 0.0525756697686587 DDX39B other 8.08943911875848e-08 1 0.000134521014538271 5.89799020704549 -1.94687095608885 0.0897456806283003 -2.44169195631036 1.92852451072441 -1.26609329709436 0.206558992579829 11.5005368490084 6.66317257615083 1.72598513959727 0.0854815192783072 SH2D1B other 1 1 1 -1.26609329709436 1.72598513959727 0.0204937105809316 13.1989980212365 5.24017004665474 2.51881101256678 0.0123511939502904 -10.6357140575378 19.5638459060694 -0.543641271179623 0.587135283896254 ARC other 1 1 1 2.51881101256678 -0.543641271179623 7.94995993908021e-16 222.099161939784 26.4333636980472 8.40222850473592 2.4981554079004e-15 -191.553251634091 129.240139038172 -1.48214984183446 0.139462298981142 NUDT16 other 1.07364208977278e-11 1 3.67028992528726e-11 8.40222850473592 -1.48214984183446 4.20141615146622e-09 273.172280719431 49.8302406206892 5.48205823043953 9.62348974036957e-08 -176.322656053202 145.355081853369 -1.21304775729185 0.226167859680681 TLK1 other 4.37409435529149e-05 1 0.00113884377587533 5.48205823043953 -1.21304775729185 2.55232456312693e-15 292.591247446594 103.608360965803 2.82401193030326 0.00510011193646745 -731.949070387424 152.635943735141 -4.79539125893915 2.70113736042268e-06 LRBA other 3.40250387510452e-11 0.0420215939160957 1 2.82401193030326 -4.79539125893915 0.57331028669377 13.2841982658211 15.0159420242517 0.88467298584173 0.377196882801009 -19.2604954684675 51.5567958600537 -0.373578209180191 0.709039892731335 ZNF536 other 1 1 1 0.88467298584173 -0.373578209180191 0.0569821524779581 21.7870830932348 9.84739132478788 2.21247255995528 0.0277678738695633 -7.89978794514242 20.3916424477924 -0.387403219989161 0.698761798780085 MMP17 other 1 1 1 2.21247255995528 -0.387403219989161 6.35419561405689e-11 316.737036085091 69.1461345838796 4.58069041734885 7.1391086260095e-06 -283.294246202847 128.811775042153 -2.19928842770888 0.0287213913649533 BAZ1A other 7.29588740406012e-07 1 0.0742395906018728 4.58069041734885 -2.19928842770888 0.100954743870953 249.116723635379 131.31657789248 1.89706987216308 0.0588857277787766 57.5589101501657 224.830849225542 0.256009841836361 0.798138176945941 AKR1C4 other 1 1 1 1.89706987216308 0.256009841836361 1.02337178654196e-19 198.811833231326 41.3994428476814 4.80228282208539 2.58918069965998e-06 -348.86799188237 65.1158955575703 -5.35764714429719 1.79341051784483e-07 COPS8 other 1.48961997249048e-15 0.00282838772769309 0.02786994105114 4.80228282208539 -5.35764714429719 0.107651478775109 -90.555381840638 110.185149415002 -0.821847429725488 0.411880909984278 -388.170976321404 183.874795984977 -2.11106135695247 0.035676153519527 CCDC69 other 1 1 1 -0.821847429725488 -2.11106135695247 9.18203508730724e-05 157.338645600039 37.3786245427341 4.20932143771522 3.48742325032552e-05 -92.9844385299602 107.720502355368 -0.863200936653692 0.388790286026919 MDM4 other 0.683969793653517 1 0.341941849694418 4.20932143771522 -0.863200936653692 0.118915257533062 37.4819643339642 18.1541279791506 2.06465242379094 0.0399107653854013 18.8540415272381 50.195328089901 0.375613473299149 0.707499198851855 RYR2 other 1 1 1 2.06465242379094 0.375613473299149 1.32997675819883e-29 397.880065116399 33.1627370481364 11.9978053843646 2.46927147378997e-26 -280.649410254556 109.688204239422 -2.55861067468994 0.0111189620563928 KLHL9 other 2.08048264285042e-25 1 3.86934839942889e-22 11.9978053843646 -2.55861067468994 0.257899560372243 -65.2964418493008 48.0598205163506 -1.35864930721258 0.175379268050813 52.1698578749346 114.500743814385 0.455628986651005 0.649018983420254 FAM3D other 1 1 1 -1.35864930721258 0.455628986651005 3.5553729511633e-15 447.042919693534 54.8070556624698 8.15666731755589 1.37335899720638e-14 -281.134965384341 242.448304321121 -1.15956663904722 0.247265087816188 NCOA6 other 4.7243795775058e-11 1 1.99713865373752e-10 8.15666731755589 -1.15956663904722 3.16647932691614e-08 248.764222738742 52.2935151865683 4.75707593668589 3.19140224802896e-06 -225.646795847476 131.912312126875 -1.71058176609357 0.088298541575471 STK39 other 0.00031303814625893 1 0.0341001330201895 4.75707593668589 -1.71058176609357 8.32602882984913e-12 329.381922543274 61.9550676063501 5.31646458101054 2.21386860596313e-07 -354.284643290828 121.634128663448 -2.91270753680577 0.00388153988303078 C6orf89 other 9.90381129310554e-08 1 0.0025638812325659 5.31646458101054 -2.91270753680577 0.77219539845758 0.136438360807614 3.95362296468426 0.0345097046497224 0.972496202209601 -7.1206302891297 10.6866918246425 -0.666308190221244 0.505783046961624 FAM19A2 other 1 1 1 0.0345097046497224 -0.666308190221244 3.04318346050569e-12 327.587643678163 61.5214596198237 5.32477034359253 2.11880381136101e-07 -232.947831765934 107.108744235989 -2.17487221447286 0.0305013269028581 TTC37 other 3.67981744044348e-08 1 0.00245717678003537 5.32477034359253 -2.17487221447286 0.000118825514508886 81.0706854886574 18.9591449773998 4.27607287065412 2.75924924764596e-05 45.6610899464502 53.3485708559909 0.855900902569776 0.392917090520085 TUSC1 other 0.871703974437191 1 0.273276045486856 4.27607287065412 0.855900902569776 0.0893707326374224 226.919778726053 286.265699925466 0.792689374888906 0.428678765157928 -453.612069908765 411.227141767864 -1.1030693838901 0.271013062372043 PAPSS2 other 1 1 1 0.792689374888906 -1.1030693838901 1.13307261584611e-18 219.829549010744 34.1614659476169 6.43501509413647 5.60325971142112e-10 -180.256858722488 63.0821942024273 -2.8574918961134 0.00460245297518549 FAN1 other 1.62301321493797e-14 1 7.30104740398172e-06 6.43501509413647 -2.8574918961134 0.819844854710431 89.6091648555012 210.957165637952 0.424774217005218 0.67133585835704 -57.0287240070853 341.215090560005 -0.167134237566953 0.867388158200791 ABCA4 other 1 1 1 0.424774217005218 -0.167134237566953 2.02515612494511e-08 601.113745156967 99.0487367707444 6.06886836475551 4.2907271092303e-09 -85.3755192427512 272.701942710213 -0.313072647720282 0.754464509770923 IPO9 essential 0.000202495360933261 1 5.40974873931757e-05 6.06886836475551 -0.313072647720282 1.18361741918313e-08 100.236915173677 23.5702607817094 4.25268587827681 2.91723743570159e-05 -180.217382954719 55.3005656625282 -3.25887051598162 0.00126242718557114 CEP290 other 0.000119995133956786 1 0.288339748144745 4.25268587827681 -3.25887051598162 4.76869426568692e-05 227.457208105161 50.672443243033 4.4887752306365 1.05882694774241e-05 -68.3152563937192 168.890385835647 -0.404494643408532 0.686166905270695 GLMP other 0.365854224063501 1 0.108540350413074 4.4887752306365 -0.404494643408532 5.04279351244428e-16 94.9399725942623 15.6595342936117 6.0627583690655 4.75072622579185e-09 -68.1915810851297 28.4149592226183 -2.39984793048195 0.0171140804447619 TOGARAM1 other 6.84256651703564e-12 1 5.98021417302678e-05 6.0627583690655 -2.39984793048195 0.0557197835745501 117.908621723623 51.3604544789404 2.29570830164616 0.0224591637181827 0.0890713110532588 96.8174250653112 0.000919992563251635 0.999266631599391 DLL1 other 1 1 1 2.29570830164616 0.000919992563251635 3.54815175384339e-09 146.159522107297 31.4888027042845 4.64163478935356 5.46933087065791e-06 -128.664682931736 65.4782072566429 -1.96500008663085 0.0504707446666058 ANKRD13B other 3.71030228899403e-05 1 0.0573732808332014 4.64163478935356 -1.96500008663085 2.20446572308681e-06 173.785888475305 39.0686870430502 4.44821419987337 1.27012479629893e-05 -55.7179895616966 70.3983043292736 -0.791467778841479 0.429370989690334 ECI2 other 0.0190752419018702 1 0.129349509255084 4.44821419987337 -0.791467778841479 5.00956956148501e-12 270.733120498076 80.2142162389414 3.37512642013006 0.00084916510738936 -916.276385571991 212.505487617676 -4.31177752557848 2.29203868116927e-05 UNC13B other 6.00246624857134e-08 0.349512978491502 1 3.37512642013006 -4.31177752557848 3.15631176858997e-08 176.628414169336 99.8574846683221 1.76880495994876 0.0780471323431335 -504.494704156062 139.823120122735 -3.6080921646808 0.000367002549741579 LDB1 other 0.000312127670795862 1 1 1.76880495994876 -3.6080921646808 0.005919315955168 264.345661974423 117.903930675762 2.242042826387 0.0257647477831761 -309.702294599319 216.750912528136 -1.42883963433888 0.154197693685675 PPP1R14C other 1 1 1 2.242042826387 -1.42883963433888 2.07450729106249e-17 249.85752213573 61.2352802082483 4.08028707121152 5.93861682890587e-05 -428.507135596393 95.3184635010328 -4.49553129433051 1.0337807644263e-05 CTR9 essential 2.90866667279871e-13 0.158995481568765 0.570005062617788 4.08028707121152 -4.49553129433051 0.746099424341754 25.7573185194428 75.3519025650951 0.341827049385933 0.732746954070816 -60.1095229178374 137.378519358301 -0.437546737281859 0.662064678250309 SMOC1 other 1 1 1 0.341827049385933 -0.437546737281859 0.449392109097145 -43.0103863002501 37.907914039289 -1.13460176826593 0.257541101426974 -83.24559400147 131.522252545078 -0.632939235685143 0.52730508575792 F5 other 1 1 1 -1.13460176826593 -0.632939235685143 0.000158126899873907 87.8305965478516 77.5529089023555 1.13252485033716 0.258418577735938 -388.132563034408 142.111802550162 -2.73117753817391 0.0067265715899897 MSRB1 other 1 1 1 1.13252485033716 -2.73117753817391 7.35466525461631e-13 187.836060497417 28.8788425793708 6.5042793865844 3.74824227212208e-10 -138.549568100356 64.2490456316017 -2.15644554309472 0.031928673165637 ZNF652 other 9.1124302504696e-09 1 4.91581973988811e-06 6.5042793865844 -2.15644554309472 3.32299504037843e-14 317.315478336097 43.7314112100324 7.25600819996638 4.37303248725262e-12 -532.750560161488 199.632892975334 -2.66865120382397 0.00808358337345836 SMURF1 other 4.29895868373758e-10 1 6.06889448580919e-08 7.25600819996638 -2.66865120382397 1.00561838521833e-08 207.742591680157 75.2840202515173 2.75945135483077 0.00618746787337356 -378.485063286947 107.656902671634 -3.51565997065113 0.000514610178283709 SLC5A3 other 0.000102462457269895 1 1 2.75945135483077 -3.51565997065113 2.28578852057127e-29 75.3248492793126 12.314453007211 6.1167840126723 3.32447090867338e-09 -104.0560929271 17.750459239708 -5.86216342472566 1.32431396462364e-08 GPATCH3 other 3.57223029994877e-25 0.00021031430072188 4.21276953547091e-05 6.1167840126723 -5.86216342472566 2.20570443090056e-14 764.213217719638 117.761206823274 6.48951584596536 4.18995470184471e-10 -493.062451244224 258.384288970017 -1.90825244526164 0.0574350708048824 CDC42BPB other 2.86675404884145e-10 1 5.4880026684762e-06 6.48951584596536 -1.90825244526164 0.0850845453937404 3.27418924340573 2.42097138602899 1.35242789828104 0.177370059430246 -8.403622406242 6.61609359114443 -1.27017888886731 0.205114407844915 OXCT2 other 1 1 1 1.35242789828104 -1.27017888886731 1.43827481661386e-05 1788.60472929996 386.845397157741 4.62356471717468 5.82693202432432e-06 412.237136603432 754.613978152875 0.546288762914909 0.585313626141425 RPL10A essential 0.116284518923231 1 0.0609613628384811 4.62356471717468 0.546288762914909 0.00218180017869839 176.326690000829 49.8032583933406 3.54046493521008 0.000469713218713256 27.8328355176002 153.220712912669 0.181651912385136 0.855991200737337 COLGALT2 other 1 1 1 3.54046493521008 0.181651912385136 0.164785831992265 28.4552032347307 18.6749872628817 1.52370670106362 0.128743780580291 -39.0177484571186 56.2067809949348 -0.694182227952794 0.488160395055938 APCDD1L other 1 1 1 1.52370670106362 -0.694182227952794 0.284184770720891 0.0723825717939596 23.7527455190063 0.00304733495906993 0.997570824227505 126.426408266481 79.6321185963158 1.58763085165902 0.113535863553793 RCSD1 other 1 1 1 0.00304733495906993 1.58763085165902 0.00664539547706402 240.589306230504 95.9815877392983 2.50661936207998 0.0127885482962041 -281.147601235914 222.065236047546 -1.26605859719401 0.206603945570973 RASSF9 other 1 1 1 2.50661936207998 -1.26605859719401 0.0018968418374964 76.3694397290525 27.8612453285472 2.74106339571271 0.006529829335049 -29.9781812413478 43.6154889499855 -0.687328789910488 0.492461190674145 FAM169A other 1 1 1 2.74106339571271 -0.687328789910488 1.15617709576147e-15 72.0373301243483 13.0282120846962 5.52933354600267 7.60494378223953e-08 -86.9403655034095 25.4672347664464 -3.41381254387128 0.000739353254859528 ZNF830 essential 1.55528942921834e-11 1 0.000904912260648682 5.52933354600267 -3.41381254387128 0.0104418061519145 6.46300531884118 3.40253027601068 1.89947033371258 0.0585682927893479 -8.5117299629637 6.54121311416384 -1.30124639182494 0.194283421582242 GRIN3A other 1 1 1 1.89947033371258 -1.30124639182494 2.25092102440895e-27 523.457886689254 79.6421327342749 6.57262517612085 2.52618913618862e-10 -596.945755103271 133.954348133746 -4.45633727773625 1.22117314379337e-05 CNOT7 other 3.48892758783387e-23 0.187596618349537 3.33179085171917e-06 6.57262517612085 -4.45633727773625 7.00637757975126e-14 535.073245773645 101.451005025043 5.27420349992158 2.71655493137003e-07 -1065.62575401683 248.137010561518 -4.29450548954946 2.43578299170956e-05 TMEM184B other 8.97376840414541e-10 0.371091538786951 0.0031311012138971 5.27420349992158 -4.29450548954946 8.89728609748124e-16 528.033439348549 93.8072521061748 5.62891916662157 4.49634874602868e-08 -394.387356077916 146.893552324054 -2.68485137596699 0.00770017886343766 MTOR essential 1.20015492168924e-11 1 0.000541315425534393 5.62891916662157 -2.68485137596699 0.0154310157402446 122.058248149281 58.5440517283108 2.08489581000858 0.0380288628688978 -115.305652437303 109.853839299964 -1.04962787984544 0.294838360396982 SCAMP5 other 1 1 1 2.08489581000858 -1.04962787984544 0.135909333060875 -44.3218229000905 28.0438647742019 -1.58044632068198 0.115259004168808 -115.716946164957 65.4747082530306 -1.76735336823132 0.0783793278222886 ZNF521 other 1 1 1 -1.58044632068198 -1.76735336823132 0.21814994462417 -25.0809668841945 50.5547397634098 -0.496115042853954 0.620215372625491 -142.550249824037 84.6946523187698 -1.68310803482034 0.0935057916878712 ALPK2 other 1 1 1 -0.496115042853954 -1.68310803482034 0.0791849328708814 8.07300942831432 4.04299872073366 1.99678752973965 0.046859559611166 -10.7795898381726 12.8264993294191 -0.840415577261082 0.401424567170431 BRINP2 other 1 1 1 1.99678752973965 -0.840415577261082 6.99328466865672e-16 134.118865852694 28.8033417156019 4.6563647779815 5.03781256431575e-06 -119.51463587663 42.3937017374707 -2.81916018131047 0.00516880029190607 LRIG2 other 9.45142422968956e-12 1 0.0529675613012158 4.6563647779815 -2.81916018131047 2.37402849144037e-06 332.073621654037 83.1492414593194 3.99370596563414 8.37703727962695e-05 -174.929467659866 177.304512615581 -0.986604712307214 0.324713262853344 PNP other 0.0204736217101817 1 0.791881334043135 3.99370596563414 -0.986604712307214 0.00375898021191581 189.838167089233 91.3415158543866 2.07833388042155 0.0386633643342909 -191.34583787668 170.848669661972 -1.11997265331514 0.26376290856752 PAX9 other 1 1 1 2.07833388042155 -1.11997265331514 1.07780598692787e-21 427.859926427902 53.5447471046265 7.99069842634355 3.83368781106098e-14 -290.139699026727 103.568218846728 -2.80143563592716 0.00545284364026924 FOXJ3 other 1.60765541010162e-17 1 5.53392835526652e-10 7.99069842634355 -2.80143563592716 9.48658433544853e-19 432.192249310379 49.2536294707272 8.77483048365486 1.92534680556195e-16 24.4328297554398 109.368406331014 0.223399339673026 0.823392404995701 ZNF358 other 1.36066079123338e-14 1 2.86857420560675e-12 8.77483048365486 0.223399339673026 1.81281319926897e-12 255.460504435265 35.8263285498343 7.13052424782853 9.16513367659851e-12 -49.0093679441737 67.2547736614372 -0.728712108836892 0.466809364803834 SFT2D1 other 2.21326363498748e-08 1 1.26268046662498e-07 7.13052424782853 -0.728712108836892 0.270029247109396 1.89031071968377 11.661611025862 0.162096876279926 0.871350358183717 63.3554630275551 39.0960611897464 1.62050756775905 0.106286261137789 CD247 other 1 1 1 0.162096876279926 1.62050756775905 2.47814380390501e-22 205.638254702563 22.9751107627884 8.95047936115396 6.89619783537982e-17 -86.1644778565572 43.1756984034099 -1.99567073707723 0.0470130342896545 CHAMP1 other 3.72068510718298e-18 1 1.0312574243027e-12 8.95047936115396 -1.99567073707723 0.000160903774657597 216.087544241562 63.9104006750427 3.38110138505117 0.000828706400992562 -24.1645504761066 88.7365873396948 -0.272317780078714 0.785585820344168 INPP5F other 1 1 1 3.38110138505117 -0.272317780078714 3.68091628636223e-10 314.255468206352 52.5157398769302 5.98402438855103 6.92477947679874e-09 35.5730849523233 96.085510118438 0.370223199194913 0.711507523641264 ARHGAP11A other 4.07330196248844e-06 1 8.65320443420771e-05 5.98402438855103 0.370223199194913 0.88405439521675 9.18784355809234 21.9890692495148 0.417836855841229 0.676402227912139 -34.7490984722219 143.985819581224 -0.241336949522446 0.809479208156251 SUCNR1 other 1 1 1 0.417836855841229 -0.241336949522446 4.09306556955872e-16 1674.43941726655 329.850965337116 5.07635142299865 7.15980823751609e-07 -1484.71898796067 474.714557833388 -3.12760365879018 0.00195444163548899 HMGN2 essential 5.56738778771377e-12 1 0.00801612130272301 5.07635142299865 -3.12760365879018 0.0854128607179521 140.530342563049 67.8726472731881 2.07050038872674 0.0393524595887216 -32.4633018744644 216.396343718742 -0.150017792891446 0.880862168049779 SELENOM other 1 1 1 2.07050038872674 -0.150017792891446 0.000729454500386249 221.13328459076 64.6117933287946 3.42249105307236 0.00071599601673178 -85.7286790762633 144.175453163809 -0.594613557266645 0.552596101191625 UBE2J1 other 1 1 1 3.42249105307236 -0.594613557266645 0.974344320152971 0.354982720340775 3.00503960259687 0.118129132153203 0.906052209170407 -1.50118923236119 8.41700623646455 -0.178351921121035 0.858578881845035 GJC2 other 1 1 1 0.118129132153203 -0.178351921121035 3.66174579502863e-29 550.069474591063 42.7122919270924 12.8784818087028 6.54628694575935e-30 -66.2278421320018 332.158757347029 -0.19938610880221 0.842110798589065 OPA1 essential 5.71818223351672e-25 1 1.03208759986842e-25 12.8784818087028 -0.19938610880221 2.59951460058519e-06 246.397387879487 47.4789801629733 5.18960995020784 4.1177497157565e-07 75.2069504902982 163.018127830265 0.461341026861772 0.644921309674561 DENND4B other 0.0223454275066303 1 0.00468846982636035 5.18960995020784 0.461341026861772 0.120962792097317 47.5019846679248 23.3053398542656 2.03824466688609 0.042503491340272 31.9421271550642 42.4113843063876 0.753149836475708 0.452018515536343 RYR3 other 1 1 1 2.03824466688609 0.753149836475708 9.28400290617229e-16 101.995301857196 13.3541582105097 7.63771854798948 3.92114125800898e-13 -70.2544771566498 38.4263106614851 -1.82829097946856 0.0686174001108769 ZNF277 other 1.25176211183921e-11 1 5.57860766776938e-09 7.63771854798948 -1.82829097946856 1.70116402409859e-11 39.8503754756113 10.490862492727 3.79857952606263 0.000179961984068837 -52.3405413392579 16.8838888036252 -3.10002878768187 0.00214045634988385 KTI12 essential 2.00039877593753e-07 1 1 3.79857952606263 -3.10002878768187 5.58818729288831e-05 409.411353689509 91.16318667981 4.49097238260739 1.05015698523338e-05 -107.339627080593 598.093500251766 -0.179469643183564 0.857703064122456 SELENOT other 0.426043399209805 1 0.107693598835683 4.49097238260739 -0.179469643183564 0.0823341937883901 -54.4898292020867 32.3774745288081 -1.68295489364385 0.093527037347743 -184.422688531182 96.3980133296537 -1.91313785586544 0.0567763941487126 ARHGEF15 other 1 1 1 -1.68295489364385 -1.91313785586544 0.313494397623399 7.85254100397611 19.6729866899797 0.399153475154627 0.690105276369303 -74.0867529199802 59.7562333895164 -1.23981631233434 0.216152645020418 TOX other 1 1 1 0.399153475154627 -1.23981631233434 0.00839607977955221 3777.68442780314 3440.35212404428 1.09805167947818 0.273149426546496 -10616.1974421504 6178.4047373381 -1.7182748449601 0.0868802742194485 CES1 other 1 1 1 1.09805167947818 -1.7182748449601 0.134230517679184 -58.3958226195655 44.1386198810978 -1.32300970843389 0.18695565641939 48.6706182809372 78.2549275784029 0.621949566462439 0.534501804505796 CD3E other 1 1 1 -1.32300970843389 0.621949566462439 1.22440494078873e-13 144.98705592355 21.5659551404711 6.72296009980399 1.07563043236709e-10 -48.9974980237308 61.0386342384743 -0.802729265407554 0.422845188705745 RUSC2 other 1.55683088221287e-09 1 1.43575150112359e-06 6.72296009980399 -0.802729265407554 0.0791971187359204 3.8277561316876 7.56702151884196 0.505847131814869 0.613376701730843 -31.7839317356646 16.2791687005537 -1.95242965536585 0.0519205373560677 FICD other 1 1 1 0.505847131814869 -1.95242965536585 1.6172527062342e-05 470.195447535606 117.157884421644 4.0133487375327 7.77391871814792e-05 50.6525423771153 184.919523518751 0.273916682312774 0.784359648212762 OSTC essential 0.130091807689479 1 0.7379003647266 4.0133487375327 0.273916682312774 9.40495413033214e-09 78.0310289219876 83.2681492048404 0.937105359818081 0.34954493313079 -687.807244800104 145.255605591857 -4.73515112891907 3.54499363180131e-06 R3HDM4 other 9.60057717624305e-05 0.0550183011655563 1 0.937105359818081 -4.73515112891907 1.91105678703175e-11 352.329087679397 47.9029995646983 7.35505272907886 2.25397929756213e-12 38.7114683458231 147.37452891114 0.262674076937436 0.793000642429022 TSEN15 other 2.24338956229658e-07 1 3.15016146627283e-08 7.35505272907886 0.262674076937436 3.61794026106062e-17 169.69589094341 30.6919623581025 5.52900101216928 7.90771632479103e-08 -171.845664537407 44.0610888702301 -3.90016835588271 0.000122775255432167 LTN1 other 5.04811204625788e-13 1 0.000940227471017653 5.52900101216928 -3.90016835588271 4.9501327239702e-16 124.87690060939 19.2531266483882 6.48605823303223 4.22825911612685e-10 -98.5833362892459 36.1324500879102 -2.72838780789547 0.0067853239555853 RUNDC1 other 6.71931015951715e-12 1 5.5364824866565e-06 6.48605823303223 -2.72838780789547 0.00040512157585645 634.159870142518 246.758945340294 2.56995696455088 0.010753794530992 -4095.99800306513 1565.139422365 -2.61701797586562 0.009412865466933 CCDC152 other 1 1 1 2.56995696455088 -2.61701797586562 0.00322984378285761 3.22034714389538 1.18433377358498 2.71912126101698 0.00696821789925434 -1.90674804670391 2.24755319247675 -0.848366149057729 0.396982796999342 STKLD1 other 1 1 1 2.71912126101698 -0.848366149057729 0.188758766941001 -130.896616168348 87.0569122341777 -1.50357522233552 0.13385953735316 -205.882772816799 120.8744306779 -1.70327811814415 0.0896667265411321 GRK5 other 1 1 1 -1.50357522233552 -1.70327811814415 1.62073355152848e-15 121.156945138374 16.7165566772281 7.24772137454705 4.91345370360136e-12 -127.235479746457 50.359895006479 -2.52652392802025 0.0121184818867187 TYW1 other 2.17145881233786e-11 1 6.81053817856184e-08 7.24772137454705 -2.52652392802025 1.15895948456883e-34 704.227161803601 68.7008521840879 10.2506321161284 5.64988594191119e-21 -667.413858997126 189.366448154035 -3.52445676360913 0.000500035069420565 DCAF12 other 1.82999702613419e-30 1 8.68556965850007e-17 10.2506321161284 -3.52445676360913 0.136156858200832 5.16963966753201 20.4809171235677 0.252412508499593 0.800913570109789 -51.2375155397839 34.907755806007 -1.46779746668695 0.14331888816156 SFMBT2 other 1 1 1 0.252412508499593 -1.46779746668695 0.838295525657135 5.02287969625161 10.0579386884288 0.499394543141348 0.617917381981386 -10.9142193519633 45.4964026621312 -0.239891919214256 0.8106002027544 ITPRIPL1 other 1 1 1 0.499394543141348 -0.239891919214256 1.87663580530624e-17 197.153398977069 36.6711429527225 5.37625454519498 1.66016488813518e-07 -299.878205178619 69.3717728960217 -4.32276980477482 2.17698273005996e-05 SMC5 essential 2.63216938052253e-13 0.332120485297947 0.00193824250689782 5.37625454519498 -4.32276980477482 1.15769093172817e-08 130.348922936411 38.4129226364585 3.39336124381992 0.000794347025830196 -119.966877333679 56.4553807542813 -2.12498570961424 0.0344994609924227 PRMT6 other 0.000117424591205188 1 1 3.39336124381992 -2.12498570961424 0.00945163906454665 35.0131967544811 14.2552410605235 2.45616307755341 0.0146660430168766 82.3722851913454 39.4964866781302 2.08555980846155 0.0379471826382189 SHISA4 other 1 1 1 2.45616307755341 2.08555980846155 1.31292646364537e-09 84.8213934904961 26.3779479923731 3.21561758765395 0.00145822577284525 -181.711920740013 49.7647534471976 -3.65141808514768 0.000312527603533181 CIPC other 1.4098204366624e-05 1 1 3.21561758765395 -3.65141808514768 0.00270487640833172 375.791670681182 143.113450193658 2.62583055731427 0.00914642706501202 -525.94087821563 410.697942303484 -1.28060266205811 0.201452958072286 CAPZA2 other 1 1 1 2.62583055731427 -1.28060266205811 1.40518203207971e-12 524.614972788958 74.2768791151407 7.06296466731892 1.42374427915427e-11 -319.817016336987 257.352209661098 -1.24272108157979 0.215064990372448 TOP1 essential 1.72247213492331e-08 1 1.9501025391576e-07 7.06296466731892 -1.24272108157979 2.19748565742848e-13 641.688437535018 87.0749937621342 7.36937678442953 2.07786301958054e-12 -172.102997919699 209.07734536933 -0.823154692421043 0.411143791511887 PRC1 essential 2.77168865971455e-09 1 2.90589143288338e-08 7.36937678442953 -0.823154692421043 0.196237708087478 55.8218408496229 32.5175049598585 1.71667048005475 0.0871778206688779 -11.3407777948799 72.0374500359652 -0.157428917725683 0.875023624374743 MAP3K3 other 1 1 1 1.71667048005475 -0.157428917725683 6.67471040433234e-18 1773.35519374518 252.613802669271 7.02002493532352 1.80744363417065e-11 -2013.64188947532 584.351235939504 -3.44594443483608 0.000660082759259393 SREBF2 other 9.44137786692809e-14 1 2.46914874864052e-07 7.02002493532352 -3.44594443483608 6.290927637956e-24 183.882146103045 28.2412812301625 6.51111203505363 3.66186497527273e-10 -186.49862451206 44.489022692114 -4.192014416741 3.75911107894532e-05 C1orf174 other 9.56913003009487e-20 0.569655692903373 4.80400066106029e-06 6.51111203505363 -4.192014416741 0.215048460278504 23.2072724441331 13.883819085879 1.67153376895676 0.0957663015390612 -8.85465493524353 49.9905182823848 -0.177126688009627 0.859540703065468 POU3F3 other 1 1 1 1.67153376895676 -0.177126688009627 6.48768631841555e-05 58.6634916528182 28.8756392342395 2.03159109922864 0.0432042458552754 -93.231645842792 46.1467957332477 -2.02032761671513 0.0443669144950807 RASGEF1A other 0.49163686920953 1 1 2.03159109922864 -2.02032761671513 2.75884058969225e-22 319.195419582332 38.7155264880072 8.24463590030754 7.20491002589355e-15 -227.127418296893 72.1518751426399 -3.14790735303657 0.00182813611443408 SPOUT1 other 4.14046795701013e-18 1 1.05198891288072e-10 8.24463590030754 -3.14790735303657 7.12073188406811e-10 85.9154201794943 14.6568983174483 5.86177363850689 1.32707594207969e-08 -113.464573651312 57.5333060698279 -1.97215459013604 0.0496086404649745 DZIP3 other 7.76088568044583e-06 1 0.000163893878846841 5.86177363850689 -1.97215459013604 1.51487300244124e-16 151.227276821907 17.6327488544266 8.57650035569709 7.43752989929256e-16 -38.4728677009122 52.8239544306714 -0.728322370325488 0.467040528394838 KIAA0753 other 2.08128401805402e-12 1 1.09926691911544e-11 8.57650035569709 -0.728322370325488 2.53186201336967e-08 88.0152901023894 25.7531862478028 3.41764662653728 0.000727951612848434 -80.3079863481226 36.2623108131947 -2.21464061575748 0.0276106631379642 DCLRE1A other 0.000251793677229614 1 1 3.41764662653728 -2.21464061575748 0.00215319897499743 501.355256982183 223.820764435228 2.23998545553745 0.025905741944851 -363.84364372495 332.082065333393 -1.09564376311521 0.274211038126896 ATG9A other 1 1 1 2.23998545553745 -1.09564376311521 0.00075139533072442 46.8188688871396 12.2058194684404 3.83578251408645 0.000155506617012683 0.112474435829 42.7751655839871 0.00262943309028603 0.997903938704899 NOS1AP other 1 1 1 3.83578251408645 0.00262943309028603 9.3456148865062e-24 708.915519680265 106.039679091515 6.6853797159123 1.32483933439448e-10 -621.571287169471 174.413490661374 -3.56377987053914 0.000432364519333172 APRT other 1.41950544511143e-19 1 1.76495096128033e-06 6.6853797159123 -3.56377987053914 8.25456749190001e-05 60.5770428728469 14.7906541241295 4.09562973783706 5.56919148541236e-05 -4.88555815399321 31.2733641617124 -0.156221061754992 0.875975516462398 TBKBP1 other 0.617936922443635 1 0.535867604726378 4.09562973783706 -0.156221061754992 7.72176666402312e-07 121.849064267741 25.9044400198538 4.70379070824743 4.10092373695396e-06 -38.0783056297503 50.9192282723735 -0.747817807176192 0.455228194223584 CCDC167 other 0.00693646299429197 1 0.0434654295153766 4.70379070824743 -0.747817807176192 0.00489758613610522 0.502539208259876 2.36081263616811 0.212867044407031 0.831589532220783 -11.2434657567429 3.93401745624039 -2.85801115063883 0.00459143652911342 ZFP2 other 1 1 1 0.212867044407031 -2.85801115063883 0.114256552624416 4.14855242451367 7.33894130008655 0.565279412231399 0.572347981205412 -17.336488804943 11.7586529798974 -1.47436010184002 0.141536874381858 SOWAHA other 1 1 1 0.565279412231399 -1.47436010184002 0.0879570239492304 2.27624521983878 18.2976211954321 0.124401155512337 0.901089542919838 -69.7035234300858 34.0954709599974 -2.04436312118597 0.0418804606983687 L3MBTL3 other 1 1 1 0.124401155512337 -2.04436312118597 0.012310641462033 -30.8250284632979 28.0213144141087 -1.10005647871313 0.27228372724032 -117.505965432905 40.8528496147663 -2.87632237508428 0.00434314435231036 MFAP3L other 1 1 1 -1.10005647871313 -2.87632237508428 2.67089989185684e-12 249.12491683897 42.3866824968118 5.87743371653841 1.2294602063087e-08 -234.139422109361 96.7444329917087 -2.42018496433203 0.0161754950519309 NAGA other 3.23846611887642e-08 1 0.000152035049112134 5.87743371653841 -2.42018496433203 0.000186674669683271 404.034799570306 100.883314194504 4.0049715138355 8.0089134468946e-05 -316.801083658432 332.816139303777 -0.951880171199489 0.342002832823742 SMG5 essential 1 1 0.75908481649667 4.0049715138355 -0.951880171199489 1.46596692687965e-13 101.130682403101 26.5368305546278 3.81095557718988 0.000171233041813033 -138.70131942419 41.5211016747129 -3.34050190938603 0.000953316523136707 KIF1BP other 1.8588460632834e-09 1 1 3.81095557718988 -3.34050190938603 0.616211125846167 -10.3561906249464 648.485407863033 -0.0159698128891958 0.987270268673588 -2221.05095918855 2325.80089721932 -0.954961777615616 0.340451230605967 TGM2 other 1 1 1 -0.0159698128891958 -0.954961777615616 1.34102851861329e-07 346.729758699681 124.170207292694 2.79237480760879 0.00560345463939688 -655.427846508478 206.275016236206 -3.17744658789868 0.00165714830724983 PJA2 other 0.00127303837271959 1 1 2.79237480760879 -3.17744658789868 0.395203083278988 -6.32892392654201 8.519173219834 -0.742903538081285 0.458183578565553 -21.8585170017739 16.0545688291908 -1.36151379923889 0.17448224046306 RORB other 1 1 1 -0.742903538081285 -1.36151379923889 1.94892644817174e-07 138.534104986022 52.7243244281867 2.62751787696612 0.00909481617374125 -210.131616880477 81.2835069862041 -2.58516917726178 0.0102599410082407 SGMS1 other 0.00183199086128143 1 1 2.62751787696612 -2.58516917726178 0.00223411421707987 4.79926859000405 2.46479649291885 1.94712569731089 0.0525487433941687 -6.21357171881353 3.89011212797468 -1.59727316704584 0.111365888529082 SNORA31 other 1 1 1 1.94712569731089 -1.59727316704584 2.05557603176964e-06 6.25895694925145 1.5544884376404 4.0263772940969 7.35820560236843e-05 -4.46734055104909 2.95000913476541 -1.51434803994407 0.131103006010622 SNORD36A other 0.0178444555317923 1 0.700133263065356 4.0263772940969 -1.51434803994407 0.0159981740822523 3.70578887773745 1.28072005368442 2.89351983446852 0.00411790442954368 2.31290091527489 2.82979495083141 0.817338696075962 0.414450241816754 SNORD104 other 1 1 1 2.89351983446852 0.817338696075962 1.74990379759113e-18 4.47204111747136 0.470404080026998 9.50680767312795 1.22250541508177e-18 -5.65051546538733 4.12237961400786 -1.37069265678174 0.171626276044999 SNORA63 other 2.50166246903629e-14 1 1.85625222226016e-14 9.50680767312795 -1.37069265678174 0.0107084830425315 71.7708501355448 23.9032329988881 3.00255827899445 0.00293194290482658 31.2890938287177 57.1014361777426 0.547956337408442 0.584181407958425 RN7SK other 1 1 1 3.00255827899445 0.547956337408442 3.27166937619997e-05 56.1432570737347 16.1289894406144 3.48089117923038 0.000582284667115541 -60.7945545162471 39.935605668579 -1.52231457363572 0.129096261436937 ZNF525 other 0.255353794812407 1 1 3.48089117923038 -1.52231457363572 1.12341895553282e-05 356.445594475906 100.445599791642 3.54864319806237 0.000459933331757209 -371.560704410701 238.671289883419 -1.55678843731976 0.120746515762722 INF2 other 0.09156987906548 1 1 3.54864319806237 -1.55678843731976 1.25666038790445e-14 85.5793060828264 11.2613483181053 7.59938363199701 5.2461100151737e-13 -82.023380911847 48.5912750911203 -1.68802692989705 0.0925914651796638 GP1BB other 1.6439631194566e-10 1 7.43741016851175e-09 7.59938363199701 -1.68802692989705 0.0336831528480763 23.3336703603234 9.07518514533725 2.57115088966664 0.0106661077187956 -5.25936059785059 24.61834019106 -0.21363587297248 0.830990484413768 EFCAB2 other 1 1 1 2.57115088966664 -0.21363587297248 2.36698703067068e-06 248.137577376546 52.8826239493199 4.69223270037336 4.28557756291046e-06 -247.234224839883 143.344561798693 -1.72475482667482 0.0857076408226109 COX20 other 0.0204176301265653 1 0.0453499817707184 4.69223270037336 -1.72475482667482 5.62909439960481e-06 213.885648369976 42.8573881757218 4.99063656172915 1.0799705341975e-06 -11.4638623019106 114.072527273099 -0.100496259493447 0.920024934269349 CHML other 0.0470648582750958 1 0.011947714019827 4.99063656172915 -0.100496259493447 0.127995598645054 7.26668652401802 9.33646239784066 0.778312621459137 0.437061252676736 50.8112775407762 25.8551570762652 1.965227957846 0.0504053311055346 STUM other 1 1 1 0.778312621459137 1.965227957846 0.297397426538234 -45.3446574984484 30.7086442961496 -1.47660890077566 0.140941561444049 32.8632510986297 85.8893520339838 0.382623111251633 0.702299148909348 CAPN8 other 1 1 1 -1.47660890077566 0.382623111251633 3.13188702350446e-05 52.2885845100064 12.5879986979413 4.15384413080356 4.3811459119489e-05 -49.778500909077 34.3349917295094 -1.44978922089836 0.148269343409876 TATDN3 other 0.244850927497578 1 0.425847382641433 4.15384413080356 -1.44978922089836 0.195410768296157 6.42435272642544 3.76397535209147 1.70679989252738 0.089013240193015 -4.16035039454021 10.256403076967 -0.405634447410046 0.685333659295342 SERTAD4-AS1 other 1 1 1 1.70679989252738 -0.405634447410046 0.216737123580306 -21.4750334470611 14.5710410179655 -1.47381600398924 0.141709136719202 31.5892330554181 41.110516857085 0.768397857055254 0.442929943531703 CR1 other 1 1 1 -1.47381600398924 0.768397857055254 0.0136831109245867 29.7328219501403 12.9911879201436 2.28869154483078 0.0228641513268743 -23.8496580616608 24.3399073076243 -0.97985821228621 0.328026826705457 RAET1G other 1 1 1 2.28869154483078 -0.97985821228621 0.00119485154813164 12.8397421822623 4.1131380563758 3.12164143441754 0.00199527490406599 -18.1607348238347 10.9821589697047 -1.65365798054214 0.099367829511925 C1orf53 other 1 1 1 3.12164143441754 -1.65365798054214 0.170282705819703 54.6217046455776 37.5725516115464 1.45376617511364 0.14717250622329 -40.9580053668895 66.6379982483155 -0.614634389440484 0.539313804288903 SAMD5 other 1 1 1 1.45376617511364 -0.614634389440484 0.564971267737678 -0.0345866739657651 9.2925960855133 -0.00372196032706985 0.997033050495852 -17.3335937631488 16.9851177496031 -1.02051654976333 0.308393699053007 ECT2L other 1 1 1 -0.00372196032706985 -1.02051654976333 0.610499922523423 -71.4892824058452 174.000525032401 -0.410856705130821 0.681499913779863 535.631733771773 610.942937392764 0.876729561778084 0.381404367782221 FCGR3A other 1 1 1 -0.410856705130821 0.876729561778084 0.00168396994523673 78.6942331920905 36.7788603144453 2.1396593727833 0.0332755617090491 -135.76936784309 68.6014590978683 -1.97910320900608 0.0488164470118555 CENPW essential 1 1 1 2.1396593727833 -1.97910320900608 0.000216619531481808 73.1804037634564 20.5272039662363 3.56504489767946 0.000432534330649851 13.2471379873036 28.8432149933162 0.45928090853857 0.646414739714957 SPRN other 1 1 1 3.56504489767946 0.45928090853857 0.0131680331386359 47.3155929809241 25.2825921075585 1.87146922197027 0.0623573521009653 -65.4720475974556 45.8977302931227 -1.42647680352215 0.154881768899336 FAM229B other 1 1 1 1.87146922197027 -1.42647680352215 9.13702185532648e-06 7.5164291875274 9.82814311439927 0.764786297883171 0.445059389782896 -47.8982855242931 13.5730563819077 -3.52892408139846 0.000489454241746121 FANK1 other 0.0751520047600603 1 1 0.764786297883171 -3.52892408139846 0.23076424150494 -5.27328726757698 17.3971376443027 -0.303112349594125 0.7620376565661 98.9345198236379 59.2528233371195 1.66970136192075 0.0961373845337403 PRR9 other 1 1 1 -0.303112349594125 1.66970136192075 0.371121199392468 230.62846302905 199.446246793896 1.15634396102413 0.248555102670148 601.448679554782 684.527003104501 0.878633971818587 0.380375270730567 SPRR2E other 1 1 1 1.15634396102413 0.878633971818587 0.505832056485835 15.0768314856453 13.2021480935902 1.14199836108226 0.254459010607112 -7.94096578522964 48.5158380542501 -0.163677803037229 0.870106344156674 KPRP other 1 1 1 1.14199836108226 -0.163677803037229 1.42762202157604e-17 133.391956732962 17.1274475490244 7.78819823275766 1.42142467034179e-13 -2.2616928298097 23.8683395575747 -0.0947570242309524 0.92457733496942 EEF1AKMT2 other 2.00737932453807e-13 1 2.0340587032591e-09 7.78819823275766 -0.0947570242309524 0.114397660977245 9.93884754700243 5.62280688268487 1.76759539396748 0.0782538718866375 -3.73997469031717 10.5375909141816 -0.354917430442651 0.722927499969812 DDO other 1 1 1 1.76759539396748 -0.354917430442651 0.00154347105985243 70.4803293121825 22.1519245144638 3.18167973469589 0.00163593713839592 -14.1594455857442 38.8682079444386 -0.36429375920765 0.715924850140497 CCDC162P other 1 1 1 3.18167973469589 -0.36429375920765 0.977101018878205 -5.22493623436144 33.5206801560171 -0.155872023182189 0.876253017768537 -17.6316791281661 113.010186456142 -0.156018494270945 0.876137677711424 ADAMTSL4-AS1 other 1 1 1 -0.155872023182189 -0.156018494270945 0.769253868023331 5.96615575991839 11.314339844275 0.527309223696091 0.598411878422969 -1.92346172642038 15.7094290628436 -0.122439951109987 0.902641684167322 PLPP4 other 1 1 1 0.527309223696091 -0.122439951109987 0.00407102174146786 10.6898941674265 3.34075584564057 3.19984298803997 0.00154778736282665 -9.84466961044462 11.3601347656293 -0.866597959755742 0.386970669883113 HIST2H3C other 1 1 1 3.19984298803997 -0.866597959755742 0.0507924171764775 97.8391098999045 48.9021241164985 2.00071288655733 0.0464751435095731 -222.341874387425 166.290128928124 -1.3370719947155 0.182381404731971 HIST2H2AA3 other 1 1 1 2.00071288655733 -1.3370719947155 0.0890021967648456 22.2266199795744 12.5549747531306 1.77034366190439 0.077864708355819 -53.2035080162385 42.52803093985 -1.25102213388359 0.212072965395919 HIST2H2BF other 1 1 1 1.77034366190439 -1.25102213388359 0.304664088078283 -27.1982188087267 46.5533678330193 -0.584237404827144 0.559543053363627 -99.2104315893643 65.7913617535625 -1.50795528387117 0.1327223155966 PNLIPRP3 other 1 1 1 -0.584237404827144 -1.50795528387117 0.00294970111257279 10.8558880681372 3.30395403400148 3.28572611979998 0.0011587979156281 -10.3281561090222 11.234991367202 -0.919284739209767 0.358808658409584 HIST2H3A other 1 1 1 3.28572611979998 -0.919284739209767 1.15899169219473e-10 411.89396339445 141.640178634154 2.90803052754078 0.00393825451549689 -835.409488122741 241.153797766835 -3.46421866816494 0.000617948131218773 ATP1A1-AS1 other 1.31418067977961e-06 1 1 2.90803052754078 -3.46421866816494 0.12195372010177 2.12995072675081 11.1056803421773 0.191789306114066 0.848051404337345 -25.1032757976101 15.7403489019658 -1.59483604550055 0.111918749773823 RBM20 other 1 1 1 0.191789306114066 -1.59483604550055 0.0268778437978796 304.270446956075 128.372126685261 2.37022206309689 0.018475123892272 -152.730780888776 306.746732981929 -0.49790515910001 0.618953200706277 SNHG5 other 1 1 1 2.37022206309689 -0.49790515910001 0.42388587934535 3.81701892907629 3.95684819137435 0.964661453880674 0.335568134630055 -5.11274408394536 9.45828402718912 -0.540557258509904 0.589253524528618 RIPPLY2 other 1 1 1 0.964661453880674 -0.540557258509904 0.891165190712725 -7.19027951771852 18.7045901858701 -0.384412566448542 0.700971954098097 -0.504803439847825 27.4863564787112 -0.0183656004112006 0.985360609868927 CHIAP2 other 1 1 1 -0.384412566448542 -0.0183656004112006 1.73929855863856e-08 276.077196125143 55.1163639450494 5.00898782801402 9.98248576094491e-07 -342.430596290818 153.538664765595 -2.23025644265958 0.0265648966155728 PCMTD2 other 0.000174590789316138 1 0.0110735714546162 5.00898782801402 -2.23025644265958 0.187344547546571 -1.70542387918739 12.349090726631 -0.138101170113652 0.890264554274079 -62.7601738477855 34.7678715860173 -1.80511981277064 0.0721824032754305 SOX18 other 1 1 1 -0.138101170113652 -1.80511981277064 0.0245452624240266 -8.97281990230913 15.9650716576322 -0.562028163401296 0.574561376414164 -122.348106584499 44.7062990070797 -2.73670845723829 0.00661603292007956 LIME1 other 1 1 1 -0.562028163401296 -2.73670845723829 0.245824596341073 0.854231858953977 2.82821524129526 0.302039196480236 0.762858202224559 -9.59311743533728 6.51627038023184 -1.47217915702816 0.142154662704911 OOEP other 1 1 1 0.302039196480236 -1.47217915702816 0.00362120352349993 9.0708039947741 4.11632228112919 2.20361851557595 0.0283861861199894 -7.42425146917066 7.06592292421361 -1.0507122068554 0.294319981081702 SAMD13 other 1 1 1 2.20361851557595 -1.0507122068554 7.17810903877005e-31 46.8847729131001 4.19614478696421 11.173297227196 4.04913971683086e-24 -44.2060379832528 12.9599688850195 -3.41096791014297 0.000745262798336583 EFCAB7 other 1.12631708927341e-26 1 6.31017933470921e-20 11.173297227196 -3.41096791014297 0.950922525640153 -2.30107688299995 22.9567914949839 -0.100235125779783 0.920231499650682 8.22114815339587 40.6663904360706 0.20216075400938 0.839942173762699 LDLRAD1 other 1 1 1 -0.100235125779783 0.20216075400938 3.44528424846143e-11 67.7834255167939 11.0018066394946 6.16111769074935 2.67231411509272e-09 -24.907394246516 20.8223877066954 -1.19618338671636 0.232694164412154 ARRDC1-AS1 other 3.99894142718918e-07 1 3.39731293451738e-05 6.16111769074935 -1.19618338671636 1.30552819066966e-06 25.4873149328468 11.7089168626648 2.17674403463535 0.0303629663600953 -61.7093500787728 20.5523842964482 -3.00253971454968 0.00292730470677991 ZYG11A other 0.0115225918108504 1 1 2.17674403463535 -3.00253971454968 0.0393806360920898 9.16811275235957 4.24735070374999 2.15854856163985 0.0317698401616958 -10.3944957040674 14.2874556959256 -0.727526014798539 0.467536512497137 LINC01270 other 1 1 1 2.15854856163985 -0.727526014798539 0.77358141045428 -1.72252867119231 3.47870087882436 -0.495164353358959 0.620885351955257 1.91983888069615 6.52742971753743 0.294118659836055 0.76889237957213 LCN6 other 1 1 1 -0.495164353358959 0.294118659836055 0.368181233136236 77.9233552328702 84.7579158254376 0.919363748789629 0.358722927057453 -215.566461908192 281.699211922012 -0.765236297387553 0.44479675355337 SLC12A5-AS1 other 1 1 1 0.919363748789629 -0.765236297387553 2.59624728869156e-07 14.5106104484423 2.72365223312002 5.32762967018737 2.09960986258818e-07 -0.538212139643847 6.64704656880723 -0.0809701171900208 0.935525703838051 LRRC73 other 0.00241970247306053 1 0.00243575740158855 5.32762967018737 -0.0809701171900208 5.99188638946712e-16 111.68158221381 13.7813335979585 8.10382982314237 1.83828723375878e-14 -1.941407616187 27.7380411849468 -0.0699907972319466 0.944252603269403 FOXO6 other 8.11601011453321e-12 1 2.66772243363075e-10 8.10382982314237 -0.0699907972319466 3.75088392374237e-15 160.952569357588 23.6033663104855 6.8190514539482 5.91355334422928e-11 -265.834436147539 80.6272691603787 -3.29707850601709 0.00110691299170477 SYS1 essential 4.98079876233749e-11 1 7.96437364400799e-07 6.8190514539482 -3.29707850601709 1.07142698167834e-07 63.806105109138 37.9859927309239 1.67972719736753 0.0941670802642721 -224.358077115132 57.7668549747794 -3.88385480243099 0.000129366364054589 INPP5B other 0.00102449847988083 1 1 1.67972719736753 -3.88385480243099 0.0249897766351826 -3.43652636454642 2.99918757806242 -1.14581908436902 0.252895937678119 -13.1861894302748 4.8437551772833 -2.72230716616658 0.00690957938616183 NEU4 other 1 1 1 -1.14581908436902 -2.72230716616658 0.454359573762462 64.4774409650424 75.5538324638469 0.853397357386144 0.394201077954155 -177.891845948416 264.460993003912 -0.672658163791228 0.501744344798502 MAFB other 1 1 1 0.853397357386144 -0.672658163791228 1.39051930117354e-06 80.9040083003187 28.3901268793679 2.84972337897913 0.00470917131932564 -109.751030404055 45.3376037214905 -2.42075057778213 0.0161411251557321 TRAF3IP1 other 0.012243522446833 1 1 2.84972337897913 -2.42075057778213 6.67232417672809e-10 202.051853637466 71.8656025047449 2.81152382496376 0.00528814985751625 -408.369458939433 109.886656958214 -3.71627884807453 0.000245241962066458 GIGYF2 other 7.28284183889871e-06 1 1 2.81152382496376 -3.71627884807453 0.0755364581852138 21.0661533616551 9.98008847979564 2.11081829628092 0.0356972364404115 5.9650391298666 15.485486250691 0.385201926068058 0.700387764537899 C2orf72 other 1 1 1 2.11081829628092 0.385201926068058 6.1592486810414e-18 63.5827024956641 19.0370787369182 3.33994009135232 0.000955619963048884 -150.982859254701 29.7860703033807 -5.06890830904821 7.4202239672775e-07 RUFY2 other 8.71780058314599e-14 0.0116371372478813 1 3.33994009135232 -5.06890830904821 0.288339593048023 6.23767266135483 15.9961886389984 0.389947430736563 0.696880592879321 -37.4074472709448 30.6669865579639 -1.21979533920755 0.223599062260258 GGTA1P other 1 1 1 0.389947430736563 -1.21979533920755 3.57926558311552e-17 303.240786022317 68.2505342287351 4.44305366176381 1.29189227121674e-05 -434.795716445118 99.0655464252284 -4.38897005199772 1.63130220308366e-05 PHACTR4 other 4.9948651212377e-13 0.249882871468356 0.131475876441728 4.44305366176381 -4.38897005199772 9.84741078012316e-17 60.79518755723 10.9282676024903 5.56311299911583 6.33759033719083e-08 -44.4552457515278 16.9426340455427 -2.62386861641641 0.00918478375797525 TIMM23B other 1.35874573944139e-12 1 0.000756771662163957 5.56311299911583 -2.62386861641641 0.207031406288104 143.679775709138 87.9579493715218 1.63350529128704 0.103523973421272 46.4703582648069 126.785492966131 0.366527409229863 0.714257563351867 ZDHHC18 other 1 1 1 1.63350529128704 0.366527409229863 0.60412272812235 -5.95320130107257 25.7745876205575 -0.230971738082218 0.817511038290288 -37.2269063856169 40.3691545078696 -0.92216215175772 0.35726424592336 C10orf128 other 1 1 1 -0.230971738082218 -0.92216215175772 9.50498772791972e-06 27.0128554353385 12.9357422208192 2.088233900631 0.0377033790119538 -50.4607159710311 21.2477857307602 -2.37486939158934 0.0182463843722264 AGAP9 other 0.0780454542339488 1 1 2.088233900631 -2.37486939158934 0.0134361937457866 22.0547796476337 17.4707661756218 1.26238193711323 0.207888694432475 -40.4626572338455 28.7513219464056 -1.40733206317506 0.160466460802323 GPRIN2 other 1 1 1 1.26238193711323 -1.40733206317506 2.45444647476206e-09 252.21487133392 61.1509162560432 4.12446594058998 4.94680220865758e-05 -161.590646201757 88.1449501523192 -1.8332377058756 0.0678640506187947 TMEM57 other 2.5953317024134e-05 1 0.477663221267976 4.12446594058998 -1.8332377058756 0.0124335121435233 24.8163074039363 12.4807732639906 1.98836297070921 0.0477700060721887 -12.443207851713 20.4774625529514 -0.60765379594942 0.54392223943379 PTPN20 other 1 1 1 1.98836297070921 -0.60765379594942 0.0519563818005078 55.8367257319729 24.7884588300913 2.25252913521963 0.0250951402997121 -3.04499934498212 48.564949396506 -0.0626995267743694 0.950052337027738 ZDBF2 other 1 1 1 2.25252913521963 -0.0626995267743694 5.09962707449565e-06 8.08688655412168 1.94157999895248 4.1651060262697 4.18713786390464e-05 -2.666845122886 3.57636363615606 -0.745686231658582 0.456503266377283 GGNBP1 other 0.0428164689174655 1 0.407617871051117 4.1651060262697 -0.745686231658582 2.76468149193609e-24 434.303612654638 48.1376988659028 9.02210996550703 3.4301438413297e-17 -218.59432335037 88.6391639391515 -2.4661144536565 0.0142759089236605 DAXX other 4.21558633890415e-20 1 5.14315767568976e-13 9.02210996550703 -2.4661144536565 0.000490016182414755 470.256833803641 134.71680191777 3.490706631313 0.000563144879794997 -237.754792005444 307.073971883866 -0.774259018264698 0.439460132469566 BMPR2 ts 1 1 1 3.490706631313 -0.774259018264698 0.00035913215265933 25.6402565833368 62.137409594339 0.412638002625599 0.680196913034595 -276.633131869632 91.892566486063 -3.01039727638457 0.00285410653571508 TCEA3 other 1 1 1 0.412638002625599 -3.01039727638457 1.00832007286964e-20 336.576798424503 38.5531425863724 8.73020396898785 2.62143174797715e-16 -95.9941544962298 70.7536436612942 -1.35673796470136 0.175989409768867 RING1 other 1.48757460350458e-16 1 3.89964186829081e-12 8.73020396898785 -1.35673796470136 5.71461126088349e-07 105.960711189915 26.6359697313528 3.97810600697561 8.91342226542042e-05 -81.8338994766187 48.8829647731833 -1.67407807313504 0.0952647064975533 HSD17B8 other 0.00519115286938656 1 0.839822645847912 3.97810600697561 -1.67407807313504 8.20300759587354e-20 316.762592657636 40.137033077215 7.89202809406098 7.31290276952955e-14 -170.903333342724 73.6604371382858 -2.32015095188589 0.0210729240307134 RXRB other 1.1963266277822e-15 1 1.05115664409218e-09 7.89202809406098 -2.32015095188589 8.70508116755181e-15 161.036016720709 21.6614527374591 7.43422053324381 1.40780894150284e-12 -61.2036247745614 48.2471712971006 -1.26854327682086 0.205700678236166 OXLD1 other 1.14332536054626e-10 1 1.97726765834074e-08 7.43422053324381 -1.26854327682086 0.131219431155118 12.374730908491 27.0466124264982 0.457533487497576 0.647654231362288 -78.1099575080404 49.7728795764446 -1.56932767749701 0.1177384455609 COL11A2 other 1 1 1 0.457533487497576 -1.56932767749701 0.300237566438222 -139.920063157575 94.3979641954997 -1.48223602436805 0.139430880718632 -22.7769249649549 185.440274585758 -0.122826203832122 0.902335095647755 HLA-DOA other 1 1 1 -1.48223602436805 -0.122826203832122 1.03889409451048e-10 865.365242078734 178.852895814828 4.83841895953797 2.19118519576309e-06 -1041.76522790877 351.3479384118 -2.96505291198765 0.00329375216980919 BRD2 other 1.18080702782061e-06 1 0.0236910943365905 4.83841895953797 -2.96505291198765 0.609964701776551 -109.774618549501 148.737651159523 -0.738041899234826 0.461122928570266 99.6704702911427 292.187984214786 0.341117621790619 0.733277421262462 HLA-DMA other 1 1 1 -0.738041899234826 0.341117621790619 0.0218685514904491 313.790687294092 113.951356594823 2.75372489341955 0.00628771444001706 146.174733933532 223.851976432465 0.652997289830196 0.514307555835763 PSMB8-AS1 other 1 1 1 2.75372489341955 0.652997289830196 0.948099888512024 -194.427356781314 628.403611709226 -0.309398853155031 0.757258557098265 20.8645383081186 1601.10715532461 0.0130313191335957 0.989612501351479 COL5A2 other 1 1 1 -0.309398853155031 0.0130313191335957 1.05234435562584e-05 737.462185920111 151.649375826263 4.86294244141817 1.95546659253143e-06 402.551760365585 297.907927714841 1.35126232945002 0.177730130992721 PSMB8 other 0.0860081041853002 1 0.0212480999944465 4.86294244141817 1.35126232945002 0.00233293977958528 272.743197655882 126.398718393506 2.1578003410349 0.0318155873560041 -438.532307022738 248.304221875339 -1.76610894374121 0.0784951937782631 TAP2 other 1 1 1 2.1578003410349 -1.76610894374121 0.394754779701242 3.03076222863179 30.2029328200921 0.100346620200261 0.92014306918412 -85.8034177905049 66.8817717671264 -1.2829118536103 0.200615047102326 TNRC6C-AS1 other 1 1 1 0.100346620200261 -1.2829118536103 0.300856803640026 -3023.05737550599 2119.989937069 -1.42597722878134 0.155021574068348 -196.675091781986 3886.78317805217 -0.050600993873949 0.959680609305692 HLA-DRA other 1 1 1 -1.42597722878134 -0.050600993873949 0.941541971994715 -8.11425611063482 129.59673754987 -0.0626115769890611 0.950122135497611 71.112499010643 251.93097247482 0.282269775375676 0.77795291043671 COL15A1 other 1 1 1 -0.0626115769890611 0.282269775375676 0.511630667894124 -18.1573961258357 57.7009846406181 -0.314680871373795 0.753245220559249 -126.17851814004 110.203986872117 -1.14495420466467 0.253234583237594 NOTCH4 other 1 1 1 -0.314680871373795 -1.14495420466467 2.20781853980282e-15 481.820984838981 66.6784620582829 7.22603626367126 5.05978365719149e-12 -188.331348757372 127.346957475588 -1.47888377147507 0.140332779246453 PBX2 other 2.94832087805269e-11 1 7.00982427867308e-08 7.22603626367126 -1.47888377147507 0.739778336893455 -798.535537119346 1139.23261537097 -0.700941604326624 0.483940867922704 26.350140284273 2175.78214832908 0.0121106519347578 0.990346244639779 AGER other 1 1 1 -0.700941604326624 0.0121106519347578 5.82859434904094e-14 264.197112887512 37.387915737333 7.06637713489074 1.34550807794976e-11 -68.0693293321334 71.4059258196635 -0.95327283486308 0.341301337920278 RNF5 other 7.48566372247328e-10 1 1.84469157486911e-07 7.06637713489074 -0.95327283486308 4.17863220156962e-17 55.9996623328813 7.34787400600513 7.62120611854734 4.23683796213514e-13 -23.9573460771404 14.0334580266833 -1.70715913580157 0.088937849714724 FKBPL other 5.82083465678647e-13 1 6.02181779558268e-09 7.62120611854734 -1.70715913580157 5.42412300086218e-18 380.826665293364 40.3541654102127 9.43710919113659 1.82974470587141e-18 29.2331532223818 92.67763908794 0.315428333199587 0.752679220135892 MRPL38 other 7.68435505532145e-14 1 2.77425892304223e-14 9.43710919113659 0.315428333199587 0.681575953204212 5.90297929042468 6.74390103386499 0.87530633394269 0.382182367483422 3.97778287077879 15.6183741605953 0.254686104320296 0.799158708203729 SMIM5 other 1 1 1 0.87530633394269 0.254686104320296 0.58530858563627 1.45113671753348 2.36524585354689 0.613524685122005 0.5400440737443 -3.61388975397072 6.47749254016595 -0.557914923338242 0.577363072778949 ERICH2 other 1 1 1 0.613524685122005 -0.557914923338242 0.571344715485453 -19.2590470258487 25.1511306333885 -0.765732853388386 0.444501676822045 28.0315166614761 68.8792079733305 0.406966303566233 0.684353979022337 SP5 other 1 1 1 -0.765732853388386 0.406966303566233 3.34517088212581e-14 91.5516101801463 14.7081953469114 6.22453047575079 1.86284360886622e-09 -71.4891786554593 28.5383137659208 -2.50502462205137 0.0128404419683467 STK19 other 4.32697853602974e-10 1 2.38332211318345e-05 6.22453047575079 -2.50502462205137 6.19777793083748e-13 114.476437428777 16.4223227691913 6.97078233315069 2.36832719903997e-11 -17.9658826163111 31.4671229926798 -0.570941379689859 0.568509052774411 DXO other 7.6994995234794e-09 1 3.2240038160531e-07 6.97078233315069 -0.570941379689859 2.14079953091441e-17 426.131231782895 54.7160103221266 7.78805379402035 1.42275435604538e-13 -175.654675109767 104.842381353334 -1.67541668590858 0.0949974489791402 SKIV2L other 3.00097278243582e-13 1 2.03581920806533e-09 7.78805379402035 -1.67541668590858 2.99580484315308e-14 37.0102016712435 7.27103423882364 5.09008766230638 6.7618178091132e-07 -53.5974695130953 13.8856934668343 -3.8599058549803 0.000142331796927899 C9orf129 other 3.88106517430482e-10 1 0.00758473103648227 5.09008766230638 -3.8599058549803 4.89921878277003e-10 81.741846279656 13.954283784226 5.85783172706128 1.35044384150351e-08 -20.7817217979313 26.054015117712 -0.797639891741813 0.425775273024282 ZBTB12 other 5.38571120789909e-06 1 0.000166685283356778 5.85783172706128 -0.797639891741813 5.91213124995389e-14 510.247884607706 93.9654751718662 5.43016340495745 1.25202405646853e-07 -388.143879008499 166.579683622966 -2.3300793384085 0.0205364584367486 SDHD ts 7.59117652494079e-10 1 0.00147225508800134 5.43016340495745 -2.3300793384085 8.93818956886875e-19 710.423858359597 86.1856128312761 8.24295186889696 7.19985900890382e-15 -255.678448115081 160.916983942496 -1.58888416779206 0.113248208841915 EHMT2 other 1.28263020313267e-14 1 1.05132341248014e-10 8.24295186889696 -1.58888416779206 0.000504608662066779 37.7738646884933 11.3517407046223 3.32758346683449 0.00099680016121756 -24.3770595125216 29.928410892759 -0.814512324087995 0.41606405613653 PKP4-AS1 other 1 1 1 3.32758346683449 -0.814512324087995 0.0244716483490288 -1.83094530232445 63.2848566980382 -0.02893180766863 0.976940350670922 -264.279676381198 113.33522842517 -2.33184050584668 0.0204448133134055 LAYN other 1 1 1 -0.02893180766863 -2.33184050584668 0.187301734913428 -41.6857075564189 80.6688413376928 -0.516751038755048 0.605749859767524 -274.061602433205 150.616631010212 -1.81959721575915 0.0699195911887838 SLC44A4 other 1 1 1 -0.516751038755048 -1.81959721575915 2.61755518543674e-10 633.849096395626 96.4105808047006 6.57447648489554 2.48565778142534e-10 125.534615053537 180.008001029225 0.697383529264098 0.486158456831329 NEU1 other 2.91831227624342e-06 1 3.27957687681259e-06 6.57447648489554 0.697383529264098 1.26614698515668e-08 575.59940604571 106.01443206398 5.42944384872368 1.25313946132458e-07 -118.187090819532 197.939332351322 -0.597087448035656 0.550945687272127 C6orf48 other 0.000128158418308518 1 0.00147344137862545 5.42944384872368 -0.597087448035656 0.0404188259289453 2731.83511073278 1085.82757200928 2.51590140198562 0.0124490755098166 2823.7383420928 2027.34647036041 1.39282475066573 0.164810166449854 HSPA1B other 1 1 1 2.51590140198562 1.39282475066573 0.012784186748852 2985.35748683688 1021.81482360015 2.92162280081102 0.00377439209649782 3260.30032232301 1907.82839687369 1.70890648638294 0.0886089428967257 HSPA1A other 1 1 1 2.92162280081102 1.70890648638294 3.40475271515897e-05 14.6848013218113 3.34485170647818 4.39026976692878 1.62222554446449e-05 2.88806209261284 6.24516587699029 0.462447619406496 0.64413006884379 HSPA1L other 0.265094046402277 1 0.163650112925578 4.39026976692878 0.462447619406496 2.86509635979441e-09 376.466953521403 70.0641209087976 5.3731774357299 1.66349425937733e-07 -152.442385955517 130.816578879563 -1.16531396296385 0.244912832405914 LSM2 essential 3.01751948613547e-05 1 0.00194179684897116 5.3731774357299 -1.16531396296385 1.37459089659328e-14 709.566761275329 114.543563839779 6.19473270683156 2.14988621600977e-09 -593.065743853627 213.864057092754 -2.77309685374766 0.00593652416090084 VARS essential 1.79535317004049e-10 1 2.74346980025007e-05 6.19473270683156 -2.77309685374766 0.0169379901505278 14.5386189899327 9.95487548278305 1.46045211867062 0.145319950929591 -31.517560837499 18.8676216074557 -1.67045754325731 0.0959791121267479 VWA7 other 1 1 1 1.46045211867062 -1.67045754325731 0.55338291394344 13.3841111939656 14.8640922633105 0.900432462129024 0.368689613458899 -8.47991096572217 32.8234060877844 -0.258349512632635 0.796333275636611 CARD16 other 1 1 1 0.900432462129024 -0.258349512632635 1.18813813277178e-05 33.2716726728374 15.2517764862221 2.18149490342281 0.0300158956021 -114.164341816143 35.3986662140364 -3.22510292127545 0.00141544522778857 MBD5 other 0.0966669184823118 1 1 2.18149490342281 -3.22510292127545 8.46815061195039e-06 104.690599022516 23.1659538868947 4.51915770590135 9.26890223911365e-06 0.851285211022382 43.9067724020896 0.0193884716286244 0.984545421624995 MSH5 other 0.0697860291930832 1 0.0954604241606315 4.51915770590135 0.0193884716286244 0.159239203424516 7.19653076569612 4.37252928022897 1.64585078897843 0.100949459313108 -1.98489563752317 8.28731891921332 -0.239509985904053 0.810890536444076 MPIG6B other 1 1 1 1.64585078897843 -0.239509985904053 0.201812955176378 -31.5642675132628 40.8018922460832 -0.773598129294917 0.439840288739964 -138.713084413625 77.3324252120188 -1.79372474137882 0.0739677814663627 LY6G6C other 1 1 1 -0.773598129294917 -1.79372474137882 4.57949804417698e-10 169.365459814662 40.0129663406544 4.23276440873571 3.15972840777963e-05 -240.266770595926 75.6268873292658 -3.17700197748253 0.00165959882067694 ABHD16A other 5.04248529644327e-06 1 0.311075261745905 4.23276440873571 -3.17700197748253 0.012492122392009 4.80716283431861 2.27428531143503 2.11370262567689 0.0354477393697596 -4.63767982448797 4.36127050451097 -1.06337816461765 0.288550181761811 LY6G5C other 1 1 1 2.11370262567689 -1.06337816461765 2.70711402299695e-27 1026.37844367034 98.2121171045625 10.4506294531621 1.00624873227438e-21 -353.98926914639 188.335916940623 -1.87956325536139 0.061232640793556 CSNK2B essential 4.19521460143837e-23 1 1.5527424187726e-17 10.4506294531621 -1.87956325536139 2.05868529242678e-27 187.015964395169 17.8053002767478 10.5033872772927 6.76037842396388e-22 -62.8677304014336 34.144234468077 -1.84124000379073 0.0666712883921976 GPANK1 other 3.19219741443696e-23 1 1.04414044758122e-17 10.5033872772927 -1.84124000379073 6.90576610137673e-14 130.183406346482 21.8629571677389 5.95451957151436 7.99957292714642e-09 -122.203164213107 42.0309675827991 -2.90745541302071 0.00394302804440234 C6orf47 other 8.84628637586359e-10 1 9.97226761098073e-05 5.95451957151436 -2.90745541302071 0.0284707119631858 0.874484976092126 13.355952962864 0.0654752961861738 0.94784457177515 -59.0226359775771 24.4564115065256 -2.41338088222094 0.0164790071918467 FAM155A other 1 1 1 0.0654752961861738 -2.41338088222094 1.30151780698535e-16 24.4250571603494 3.25827822957339 7.49630800054401 9.20193861895412e-13 -11.9559803759042 6.26395530998988 -1.9086950312108 0.0573500325726798 APOM other 1.79088850241184e-12 1 1.29701324834158e-08 7.49630800054401 -1.9086950312108 3.81268531715753e-25 1558.52763885493 165.784817850849 9.40090690485952 2.2861554990017e-18 -916.917546298651 318.717008469991 -2.87690183432738 0.00433303255911825 BAG6 other 5.84446532267078e-21 1 3.46398281208738e-14 9.40090690485952 -2.87690183432738 2.79189714163339e-15 2361.78647388351 337.074425598151 7.00672105186395 1.90591618965379e-11 -1313.9119000215 648.016832609096 -2.02758915186096 0.0435734832795307 PRRC2A other 3.71769023379903e-11 1 2.60195678211535e-07 7.00672105186395 -2.02758915186096 0.337767355747415 -60.5046877231225 42.8345755390944 -1.41251983850992 0.158935910945169 -13.0070365087624 82.3483594691061 -0.157951373805354 0.874611883218436 AIF1 other 1 1 1 -1.41251983850992 -0.157951373805354 0.0693293869034225 -3.22423301080776 2.34092192082488 -1.37733470822967 0.169536972262434 5.2695454147181 4.50720714691007 1.16913761514837 0.243367996837888 NCR3 other 1 1 1 -1.37733470822967 1.16913761514837 0.295620564983002 -41.608940411227 28.566609212285 -1.45655860315872 0.146387408162607 -2.92845026087408 55.0021015477646 -0.0532425158033456 0.957577620356254 LST1 other 1 1 1 -1.45655860315872 -0.0532425158033456 1.42842469570729e-14 129.401041210312 18.4099076419233 7.02888052059739 1.66639070022346e-11 -55.1904143562068 35.4464053497317 -1.55701019078439 0.120626547526408 NFKBIL1 other 1.86480844024587e-10 1 2.27845600441554e-07 7.02888052059739 -1.55701019078439 4.55059162237723e-07 48.1620675818405 20.4294805704223 2.35747881184846 0.0191133129198637 -185.145436997335 49.5706342050708 -3.73498221207741 0.000229022151041963 ZNF814 other 0.00416970710358426 1 1 2.35747881184846 -3.73498221207741 0.0208755993053134 61.1485700229173 22.1367529261832 2.76230982144591 0.00612917122874212 28.41638262683 42.6220670201239 0.666705878281625 0.505523084100926 MICB other 1 1 1 2.76230982144591 0.666705878281625 1.38812227236442e-10 48.2831673361579 9.75238870384228 4.95090677806301 1.30296753761689e-06 -63.8745391514885 23.4155817147739 -2.72786471545088 0.00679263120440043 ZNF551 other 1.5674676699539e-06 1 0.0143314005485775 4.95090677806301 -2.72786471545088 1.08293063766177e-05 89.1871126417939 22.4913730654564 3.96539208087624 9.37454353173126e-05 -45.5111314804427 43.3100549679176 -1.05082137425491 0.294273334679044 MICA other 0.0884429451778369 1 0.881582073724008 3.96539208087624 -1.05082137425491 7.37178746688506e-14 15.1044680787856 2.5542064961599 5.91356575965736 1.00153828483994e-08 -15.7052078072547 5.69230958671079 -2.75902207496232 0.00619091840401265 ZNF805 other 9.43736231510626e-10 1 0.000124350993445727 5.91356575965736 -2.75902207496232 0.815615258889361 1105.1526320326 1870.16917210229 0.590937252371815 0.555051385292943 20.7446409860559 3591.55501593236 0.00577594966359458 0.995395702968845 HLA-C other 1 1 1 0.590937252371815 0.00577594966359458 0.202215123167894 8.39569751791825 10.5719711556394 0.794146843035957 0.427799717631124 -25.0878989435637 20.8802347828497 -1.2015142168885 0.230593087757397 POU5F1 og 1 1 1 0.794146843035957 -1.2015142168885 9.46649281444381e-14 250.517486972991 35.1212144537432 7.13293918987163 8.83626392929526e-12 -76.9861828294418 69.3663644042184 -1.10984889421075 0.268040784920078 CCHCR1 other 1.2076404883386e-09 1 1.21772553209618e-07 7.13293918987163 -1.10984889421075 0.069181942290376 1.59973816405722 9.39786051648292 0.170223654761787 0.864960329513683 -39.6554262104616 18.7570930999949 -2.1141562820559 0.0354086341615455 PSORS1C2 other 1 1 1 0.170223654761787 -2.1141562820559 0.032082600886498 43.7078237330835 39.64152175581 1.10257683855635 0.271182000861041 -147.79026305412 79.1201053574979 -1.86792298097104 0.0628440743646128 CDSN other 1 1 1 1.10257683855635 -1.86792298097104 0.0289280625382462 54.2642773535022 40.8987693523058 1.32679486969558 0.185685253863396 -140.754483543288 81.6294328981499 -1.72431044227527 0.0857837663447368 PSORS1C1 other 1 1 1 1.32679486969558 -1.72431044227527 0.645763078196448 122.933643751929 171.068956431659 0.718620410834389 0.472989428465878 -107.131629377434 341.434769826574 -0.313768950455309 0.753936143327196 C6orf15 other 1 1 1 0.718620410834389 -0.313768950455309 0.279834648324219 -40.233032303853 25.4777435726257 -1.57914425149804 0.115460915131244 -39.998518205013 50.8507662282671 -0.786586342189244 0.43220631926643 MUC21 other 1 1 1 -1.57914425149804 -0.786586342189244 3.49108177934162e-23 358.615507965335 35.4840133519631 10.1063964892656 1.38387721444714e-20 -85.5088338274206 69.7782525106505 -1.22543673352051 0.221474651080055 DHX16 essential 5.27921386672039e-19 1 2.1243899118978e-16 10.1063964892656 -1.22543673352051 3.40323458839998e-14 116.531485197187 15.2527265199419 7.64004291592259 3.72225837651407e-13 -18.3778253759643 29.9130577541069 -0.614374683024211 0.539481310101309 C6orf136 other 4.40106296971886e-10 1 5.29714589561718e-09 7.64004291592259 -0.614374683024211 1.92237002157334e-29 595.840010358823 50.090404091978 11.8952925447501 1.49661925780466e-26 -115.597216366944 97.6049986141992 -1.18433705248911 0.237313536186056 MRPS18B essential 3.0052410547256e-25 1 2.34654933431193e-22 11.8952925447501 -1.18433705248911 0.377856853734647 84.6062682935646 71.1103264364638 1.18978877658731 0.235166908906364 -42.1595705704975 138.563931337856 -0.304260785353305 0.761161861834344 PPP1R10 essential 1 1 1 1.18978877658731 -0.304260785353305 6.33820960528876e-21 834.498801903625 91.3591690471935 9.13426436127661 1.55582407953576e-17 -360.843720369456 177.734076848292 -2.03024499729144 0.0433046082303725 ABCF1 essential 9.3723105433405e-17 1 2.34120407488542e-13 9.13426436127661 -2.03024499729144 3.76069870733415e-16 139.633177525267 16.8652793943067 8.27932785817968 5.64307813744408e-15 -23.1841433232257 32.810443606237 -0.706608651850675 0.480414565874975 PRR3 other 5.12019129003545e-12 1 8.25187316038448e-11 8.27932785817968 -0.706608651850675 0.00087399270176925 64.940373384187 19.1941325327932 3.38334505470545 0.000821832246879233 -50.4285488292466 62.1541066439098 -0.811347013933597 0.41787843503223 LINC01123 other 1 1 1 3.38334505470545 -0.811347013933597 1.17002636126593e-21 514.449963193751 53.3106157482637 9.65004729307608 3.85485313737031e-19 -145.191912016408 103.712776451996 -1.3999423888108 0.162670114035034 GNL1 other 1.74439230201137e-17 1 5.87286875478367e-15 9.65004729307608 -1.3999423888108 0.903947973769114 26.9497750861044 1189.1053556959 0.0226639085906164 0.98193498236983 -958.270708988382 2308.31587182519 -0.415138465530141 0.678367810148991 HLA-E other 1 1 1 0.0226639085906164 -0.415138465530141 0.00133814854820641 82.3339202677158 29.8138018502917 2.7616041953036 0.00614795715972141 -96.1229333180626 76.1266850700938 -1.26267068150356 0.207801025907548 ZNF468 other 1 1 1 2.7616041953036 -1.26267068150356 4.47931173817524e-09 47.9556153077707 9.67145215711031 4.95847102676452 1.24990307133322e-06 -45.3513632530103 23.1224388104796 -1.96135726100207 0.0508536043201857 ZNF616 other 4.65624455183316e-05 1 0.0137664324276641 4.95847102676452 -1.96135726100207 0.232613425738563 -21.374624592937 27.5903643718276 -0.774713385618151 0.439179500066043 -88.7731396855185 52.0970161314584 -1.70399662547878 0.0895195716516624 TRIM31 other 1 1 1 -0.774713385618151 -1.70399662547878 0.00634854880868523 27.726271838545 14.320232558008 1.93616072408266 0.0538801444233818 -45.6221965547508 27.0399251175733 -1.68721608349059 0.0927040009134529 RNF39 other 1 1 1 1.93616072408266 -1.68721608349059 8.14769378312137e-25 462.664268390482 49.1484646240132 9.41360573376754 2.08686833449016e-18 -284.847758434282 92.8037165383772 -3.0693572311459 0.00236120520694057 PPP1R11 essential 1.24594533331492e-20 1 3.16306633458674e-14 9.41360573376754 -3.0693572311459 0.537800789178751 -144.265059302141 129.804647934103 -1.11140133730326 0.267373465324435 -77.9416708062906 245.101324006664 -0.317997755100546 0.750729749649272 HLA-J other 1 1 1 -1.11140133730326 -0.317997755100546 0.613268400828089 66.2241208575354 67.9534738848712 0.974550925383658 0.330645795039928 65.9315587604725 128.311941714827 0.513838056531055 0.607780858468631 ZNRD1ASP other 1 1 1 0.974550925383658 0.513838056531055 0.0146447047656306 34.3259389098807 14.6355191096967 2.3453858146472 0.0197235415842944 -4.35041243960855 22.9178804821681 -0.189826124758505 0.849586448002137 DISP3 other 1 1 1 2.3453858146472 -0.189826124758505 9.57086452685306e-17 7678.57864437272 1106.59393342747 6.93893072465138 2.96611958437591e-11 -4335.77550005634 1802.40014399428 -2.40555656550707 0.0168257252153622 RACK1 other 1.32097072199626e-12 1 4.02472766403967e-07 6.93893072465138 -2.40555656550707 0.172750701514689 -83.8348603193799 51.481922478326 -1.62843297770542 0.104586532352184 -143.311457971425 97.7111803201298 -1.46668433951873 0.143612910486706 HLA-G other 1 1 1 -1.62843297770542 -1.46668433951873 0.00622973968782238 87.2869612662941 44.9630302772964 1.94130512841277 0.0532540068161746 -366.548745568204 173.936437933682 -2.10737180732631 0.0360006964718688 TBC1D8 other 1 1 1 1.94130512841277 -2.10737180732631 0.949235031236574 -70.7885360235737 219.71917732754 -0.322177321454502 0.747564937431086 -40.8271524712729 417.020560269099 -0.0979020133801736 0.922081941737982 HLA-F other 1 1 1 -0.322177321454502 -0.0979020133801736 0.933679247415675 0.25276337292344 10.5016199263051 0.0240689888509776 0.980815162794431 -6.69220936865991 19.9317668974903 -0.335755951947369 0.737312798732999 ZFP57 other 1 1 1 0.0240689888509776 -0.335755951947369 1.47075690693564e-11 92.8278818979938 20.3997236284547 4.55044801531096 8.11118246802453e-06 -157.835006258684 42.1744469916015 -3.74243214831281 0.000222823030336262 LINC02210 other 1.73431654465851e-07 1 0.0839264049966498 4.55044801531096 -3.74243214831281 1.91685317574441e-14 242.41557613018 53.0681007405539 4.56800927011374 7.46153175504096e-06 -524.284384838356 110.522472138302 -4.74369035269399 3.38685166276959e-06 AKT1S1 other 2.49344261100832e-10 0.0525876457678235 0.07741339195855 4.56800927011374 -4.74369035269399 0.00514391447124845 1.60868914376797 4.26781579538119 0.37693499928206 0.706514733209436 -19.6720960532243 7.20234866686289 -2.73134458815264 0.00671862332916349 FAM153C other 1 1 1 0.37693499928206 -2.73134458815264 0.757074316481809 -41.5984118445509 304.089436801614 -0.136796635496712 0.891292370602108 -421.093542949455 573.734837211411 -0.733951497517814 0.463608164071754 GABBR1 other 1 1 1 -0.136796635496712 -0.733951497517814 0.000362598134536845 63.2962865161759 19.2911489145904 3.28110507033116 0.00116950171328354 -4.04242742032829 32.4886709789856 -0.124425755148403 0.901070423976735 CASC10 other 1 1 1 3.28110507033116 -0.124425755148403 0.98164888217394 -0.421017252077621 3.75145293656051 -0.112227784593675 0.910727442750042 -1.35840621138436 7.11820648595468 -0.190835460317807 0.848800076584136 MAMDC2-AS1 other 1 1 1 -0.112227784593675 -0.190835460317807 0.522701365146174 10.9972478014881 10.5043061183454 1.04692758165927 0.29606583042474 -2.85651954655039 24.4575893032559 -0.116794812077825 0.907109162373309 SPDYC other 1 1 1 1.04692758165927 -0.116794812077825 0.942822611064448 -1.55147780246822 4.60807926054069 -0.336686440216781 0.736618758725059 -1.90313273970205 8.7436148699889 -0.217659717176503 0.827861122567972 C9orf135 other 1 1 1 -0.336686440216781 -0.217659717176503 1.49362190836958e-20 470.993505812797 49.7689363558639 9.46360401285336 1.45641492146365e-18 -104.371408803582 94.5492040458985 -1.10388458429449 0.270615248536934 TRIM27 other 2.19816336254751e-16 1 2.21040092630538e-14 9.46360401285336 -1.10388458429449 0.0112155066925084 14.2687332124245 4.92746778745275 2.89575372745373 0.00409308206337425 7.51898191724632 8.31525306258009 0.904239697897216 0.366677402515678 MALRD1 other 1 1 1 2.89575372745373 0.904239697897216 0.0863866176205957 24.660877373258 11.121152088228 2.2174750581248 0.0274172650067433 16.7603021252482 18.022860410845 0.929946842131838 0.353223189231775 RANBP17 other 1 1 1 2.2174750581248 0.929946842131838 0.423940284803899 9.12589611951345 8.08904435048633 1.12817976068641 0.260249209696235 -21.5685312559878 35.2415971904987 -0.612019118753302 0.541042051641586 LINC01291 other 1 1 1 1.12817976068641 -0.612019118753302 0.291695060001556 11.5782889970293 7.96085928698022 1.45440191562804 0.146992113473219 1.52831042589114 14.8149400937072 0.103160081392453 0.917912218036302 TTC25 other 1 1 1 1.45440191562804 0.103160081392453 5.65608289152601e-08 162.742268695556 28.5176362589945 5.70672362946022 3.03544584478473e-08 -176.02559609757 122.461504642066 -1.43739533996469 0.151767872712418 MRPL53 essential 0.000550054061200904 1 0.000368047808680148 5.70672362946022 -1.43739533996469 0.0194217282443101 35.2590377830327 13.4200660357676 2.62733713001553 0.00909401453611549 13.951892929186 22.792106057687 0.612137065959314 0.540958436436878 ST8SIA6-AS1 other 1 1 1 2.62733713001553 0.612137065959314 0.23885616390179 22.0486020188368 39.7153253464801 0.5551660933527 0.579242415642084 254.572995262218 150.408185035007 1.69254748471944 0.0916994622782729 MROH6 other 1 1 1 0.5551660933527 1.69254748471944 9.29558883180792e-06 72.8664448721173 30.8299364901421 2.36349643131494 0.0188120663342573 -217.78324184536 64.1786104506641 -3.3933929126243 0.000793857483096994 ATXN2 other 0.0763911490197975 1 1 2.36349643131494 -3.3933929126243 1.43400315186806e-08 776.993264724585 125.298230701922 6.20115112856628 2.09295494521461e-09 406.770731493973 539.847176029755 0.753492376278638 0.451810634226339 DCTN1 essential 0.000144561857739819 1 2.67165698756645e-05 6.20115112856628 0.753492376278638 0.00657774705653093 71.916379884547 33.674839253081 2.1356116756509 0.0336042564519458 -118.416490896981 72.5093942094047 -1.63311929699754 0.103600902799487 TCTN1 other 1 1 1 2.1356116756509 -1.63311929699754 0.00701097699311082 38.7917969302817 13.1065848153346 2.95971814754487 0.00335152899655071 -6.23013753264626 28.0079528874466 -0.222441731378328 0.824137579966705 FAM216A other 1 1 1 2.95971814754487 -0.222441731378328 1.65082124725826e-11 105.274820576976 23.5326282602528 4.47356833298504 1.13611430918012e-05 -93.5806514725385 37.3159782631693 -2.50779038439151 0.0127382713569351 ZBTB48 other 1.94241572558083e-07 1 0.116167688113667 4.47356833298504 -2.50779038439151 0.351087530681567 -16.63708136251 13.5713589880607 -1.22589649106963 0.221301845645767 -40.3899658324772 33.7077649758414 -1.19823921465647 0.231870754844613 IGFL2 other 1 1 1 -1.22589649106963 -1.19823921465647 0.487960180408198 -17.6676948692109 14.7431568811357 -1.19836579178081 0.23181773260889 -17.328498006397 33.2458326267222 -0.521223162041331 0.602635417218385 KRT40 other 1 1 1 -1.19836579178081 -0.521223162041331 2.24523969087005e-06 179.004821414481 43.2083966280105 4.1428248994187 4.68607212714982e-05 -91.68577002506 88.7925446241656 -1.03258410278859 0.302788523751267 MZT1 other 0.0194145876069533 1 0.453471199744288 4.1428248994187 -1.03258410278859 1.11969078154039e-14 32.8864870293227 5.33417634964063 6.16524180561415 2.52158317566516e-09 -49.8822997003785 14.8073547183775 -3.36875158656591 0.000863894429770263 ZNF155 other 1.46713083105238e-10 1 3.20921890766905e-05 6.16524180561415 -3.36875158656591 2.89023562593095e-05 149.410232646312 40.1818767562336 3.71834878576531 0.00024401690458364 -120.789057513875 82.2028475411848 -1.46940235194843 0.142892217938659 UQCC3 other 0.226796789566802 1 1 3.71834878576531 -1.46940235194843 5.54792369047778e-11 26.3438307144668 3.68874733751311 7.14167393536564 8.56092093110736e-12 -9.03886504306338 19.0666185507709 -0.474067544750766 0.635834879237169 FBXO48 other 6.38566016773992e-07 1 1.18037977798108e-07 7.14167393536564 -0.474067544750766 0.000189732334866481 47.0428499730695 13.897408286058 3.38500884515735 0.000818298938653937 -34.493654213387 35.508566347208 -0.971417822845987 0.332216169591439 ATP6V0E2-AS1 other 1 1 1 3.38500884515735 -0.971417822845987 0.564458593960128 137.100410210917 175.761465939577 0.780036792922794 0.436057570484831 -222.040001638515 531.118097224075 -0.418061449607954 0.676236964918733 CD177 other 1 1 1 0.780036792922794 -0.418061449607954 0.0781686155488418 1.59903317370991 2.1639282736947 0.738949249449804 0.460591810099334 -11.9585724101621 6.64792471446307 -1.79884293577293 0.0731813044683541 PSG5 other 1 1 1 0.738949249449804 -1.79884293577293 0.000735383739509377 53.6494802147697 25.3629075557686 2.11527326261012 0.0353192121858587 -138.682452933964 65.4101977702475 -2.12019620275548 0.0348981854143779 ZNF783 other 1 1 1 2.11527326261012 -2.12019620275548 5.44329448030875e-08 14.5106416989774 3.95779158656525 3.66634810893882 0.000296041427102261 -29.3731986314305 10.2070289000353 -2.87774228123611 0.00432423080256123 ZNF425 other 0.000530068016492466 1 1 3.66634810893882 -2.87774228123611 0.686720800357558 2.10445185089392 5.55221905894395 0.379028966356056 0.704965356234009 -16.936472552532 24.0405938108636 -0.704494767715705 0.481734169664305 FAM83A-AS1 other 1 1 1 0.379028966356056 -0.704494767715705 0.371478711237394 2.61123174395418 13.763961581799 0.189715128775657 0.849674910008595 -35.219712067581 28.1116189553029 -1.25285249930215 0.211343355818427 LRRC10B other 1 1 1 0.189715128775657 -1.25285249930215 5.95075650353721e-10 57.3558978516415 10.6611285636141 5.37990865689346 1.60401762939093e-07 -51.4688514478068 22.9927777741466 -2.23847905430892 0.025995979342755 C12orf73 other 6.51131776617042e-06 1 0.00187429459994331 5.37990865689346 -2.23847905430892 0.00131651420597679 169.561316744228 175.08993893458 0.968424101213392 0.333692916653262 -819.529548357134 302.327219137443 -2.71073689856738 0.0071404052909413 PCDHGA1 other 1 1 1 0.968424101213392 -2.71073689856738 1.52151263182095e-05 150.723300052946 35.9079628787046 4.19748958085098 3.68722568823422e-05 3.0506958626434 64.4225096348649 0.0473545020200888 0.96226635814174 PCDHA9 other 0.122770854261633 1 0.360831905850601 4.19748958085098 0.0473545020200888 1.42325385746501e-05 154.42131908444 36.5531925030936 4.2245644910871 3.29550858574648e-05 4.99450539060866 65.5801167047595 0.0761588365738023 0.939350195744555 PCDHA8 other 0.115155469607494 1 0.323717808377877 4.2245644910871 0.0761588365738023 2.01262713809131e-05 152.174127844397 36.3719179495484 4.1838356738701 3.90125812384301e-05 8.72831756587764 65.254891859458 0.13375729109591 0.8936960222563 PCDHA7 other 0.160567393076925 1 0.380567729980886 4.1838356738701 0.13375729109591 9.29441359213023e-06 158.803680624648 36.4494425764815 4.35682055470208 1.88855050116144e-05 11.8134843750918 65.3939788648224 0.180650949524141 0.856779639649263 PCDHA5 other 0.0763907853137184 1 0.189609767870842 4.35682055470208 0.180650949524141 1.2024220641696e-05 161.625219638919 37.5689828976022 4.30209196984235 2.38173087111455e-05 11.4677268971863 67.4025471973578 0.170137886089205 0.865031516298271 PCDHA4 other 0.0978170349201972 1 0.237077490910743 4.30209196984235 0.170137886089205 1.45266709756737e-05 154.600167711043 36.3519969618947 4.2528658844547 2.92868488561156e-05 9.38140007447422 65.2191515969599 0.143844251953003 0.885732783143897 PCDHA2 other 0.117419081496371 1 0.289383353547278 4.2528658844547 0.143844251953003 1.5371950360752e-05 160.148179906093 37.5366275590741 4.26645093926077 2.76679350891586e-05 13.2504690963681 67.3444984543781 0.196756519099248 0.844168892367385 PCDHA1 other 0.123944035758744 1 0.273995561187937 4.26645093926077 0.196756519099248 1.21078592382499e-17 134.999853247526 27.1660105243785 4.96943977572188 1.18678586116445e-06 -199.925850627455 43.9532630389585 -4.54860087293744 8.1302805963823e-06 TRIM13 other 1.70393903059891e-13 0.125344535954426 0.013091434834505 4.96943977572188 -4.54860087293744 0.212857078962274 -8.18905083284215 4.99734336015544 -1.63868084353272 0.102431661647555 -16.6566940120433 13.6581750672272 -1.21954023360054 0.223691786020025 PRSS1 other 1 1 1 -1.63868084353272 -1.21954023360054 2.35294889125452e-05 98.4140637272074 29.0064004872644 3.39283958278165 0.000799130552174632 -35.6752236413367 47.2653459766551 -0.754786046820795 0.451057880500309 SPIRE2 other 0.186353552187358 1 1 3.39283958278165 -0.754786046820795 0.0294752413577656 1.93230393267837 4.52405227364826 0.427117949970133 0.669632564867876 47.224606584354 17.6726727321518 2.67218248762332 0.00799254904306375 AARD other 1 1 1 0.427117949970133 2.67218248762332 0.980997610639021 2.02592902872154 12.3426437855761 0.164140605847273 0.869744642326445 -3.63504400798453 48.8295486000565 -0.0744435308578775 0.940713214886006 PKHD1L1 other 1 1 1 0.164140605847273 -0.0744435308578775 0.336384222626757 -3.87223066005073 2.9473930133353 -1.31378158343019 0.190034904828729 -6.90452926481223 5.71673118951493 -1.20777574385093 0.228190403622611 SLFN12L other 1 1 1 -1.31378158343019 -1.20777574385093 0.384746210899452 -2.5609571396218 3.70764722453767 -0.690722979973141 0.490328656383855 -11.4031678179142 8.49722971049077 -1.34198653048483 0.180719507153886 LINC02397 other 1 1 1 -0.690722979973141 -1.34198653048483 2.26914178754435e-08 70.8441304212942 15.0557094353602 4.70546610410187 4.04297511925017e-06 -71.4036700378483 40.3896229748554 -1.76787166550925 0.0782075582463131 SLC35B4 other 0.000226165361964546 1 0.042880532596056 4.70546610410187 -1.76787166550925 8.78252538993481e-08 10.2033772183925 3.35738703994664 3.03908280367777 0.00260313283429471 -13.2539717130055 5.58865645746291 -2.37158462215127 0.0184059872610838 SYCE1L other 0.000843825039464937 1 1 3.03908280367777 -2.37158462215127 0.0586753562568145 23.6862113014083 29.395927371425 0.805765064055542 0.421084778945489 -69.9127448366036 50.2278609056907 -1.39191165173993 0.165090434590257 TMEM231 other 1 1 1 0.805765064055542 -1.39191165173993 0.00175686335805838 8.14579715765189 10.7959425282202 0.754523946043532 0.451185033691067 -46.6370292977574 17.2975551362919 -2.69616306641558 0.00745015126244156 CCNI2 other 1 1 1 0.754523946043532 -2.69616306641558 0.362428989994733 2.31885145652656 2.00246320199855 1.15799953487897 0.247902894783562 -0.19667873820642 3.17164142027173 -0.0620116564720516 0.950600118459459 TMEM240 other 1 1 1 1.15799953487897 -0.0620116564720516 0.0313437718709335 3.68526823994336 3.73671177023911 0.986232941297355 0.324898518223048 -7.37809342728255 5.74219365133487 -1.2848910843624 0.199927469560404 C4orf47 other 1 1 1 0.986232941297355 -1.2848910843624 8.89422098547845e-05 112.093792308344 27.0138450185072 4.14949416610438 4.47883231160726e-05 -21.2507056427244 96.017262712132 -0.22132171905833 0.825010475027056 TRIQK other 0.663419943306838 1 0.434939405780181 4.14949416610438 -0.22132171905833 7.64767285100682e-25 77.9062059469561 6.97386857616774 11.17116061137 4.84076143258299e-24 -22.8948483145767 27.6091173001121 -0.829249557880059 0.407701180051309 SDHAF1 other 1.16978803929e-20 1 7.54190631196429e-20 11.17116061137 -0.829249557880059 2.95944130355199e-18 350.827326227287 38.5616557989971 9.09782837272279 2.11633199370974e-17 -165.493526266277 154.278555009434 -1.07269300166933 0.284370252506112 PSENEN other 4.21394847212768e-14 1 3.18084698654575e-13 9.09782837272279 -1.07269300166933 0.216803812696047 5.02185407641691 3.46308625723726 1.45010944094219 0.148180104850497 -7.76874040368136 12.6555221816199 -0.613861703388594 0.539819765699498 LINC00654 other 1 1 1 1.45010944094219 -0.613861703388594 2.64850141359184e-07 144.114961690953 30.2502759155888 4.76408751090719 3.11211950018341e-06 -104.205093764307 94.6112014269242 -1.10140334540401 0.271709347592968 ZBTB10 other 0.00246760876704351 1 0.0332778938154612 4.76408751090719 -1.10140334540401 7.03971633839516e-13 100.840472103606 21.6419919394313 4.65948201005826 4.96769339962245e-06 -77.0160575560432 31.8254432926802 -2.41995238990927 0.0161782517140761 C4orf46 other 8.72809677429623e-09 1 0.0522700699508274 4.65948201005826 -2.41995238990927 8.27376221386046e-07 536.492932664701 110.625465862833 4.84963320588329 2.10329777222734e-06 28.9279992680264 213.732648894094 0.135346655823091 0.892439778480075 LGR4 other 0.00741187809817703 1 0.0227829214687666 4.84963320588329 0.135346655823091 0.000445837346249292 238.615196289854 90.4349439713922 2.63852871258854 0.00881019966640296 -172.903949636373 162.615819503637 -1.06326647778881 0.288611151719242 PSMB10 other 1 1 1 2.63852871258854 -1.06326647778881 0.0988070778046209 53.3216036986877 27.4256081879143 1.94422684570346 0.0528990022635832 108.153053441056 101.296552654117 1.06768740502306 0.28660822853442 VIT other 1 1 1 1.94422684570346 1.06768740502306 0.0431417756962363 3.17203430303787 1.97836024589491 1.6033653676674 0.11002748662562 -11.8088830748146 8.06137531423123 -1.46487201184737 0.144123590768961 SPDYE2 other 1 1 1 1.6033653676674 -1.46487201184737 8.54106343184305e-20 599.223000305195 80.5724004338973 7.4370751904904 1.37110172766905e-12 -240.231990226846 140.321171780297 -1.71201528022429 0.0880420776808109 E2F4 other 1.2452016377284e-15 1 1.92598659685671e-08 7.4370751904904 -1.71201528022429 2.71774882401761e-05 193.714440644407 62.7466271550622 3.0872486606442 0.00223212949415434 -431.672945729458 199.96016639859 -2.15879469148362 0.0317538423823117 PDE7A other 0.213914009938426 1 1 3.0872486606442 -2.15879469148362 5.31026358357037e-05 55.4765930305112 13.2517838813639 4.18634906267437 3.8316235480236e-05 -2.03780020061298 25.4830457442251 -0.0799669011729016 0.936322383715896 TMEM170B other 0.405544829877269 1 0.374081406993544 4.18634906267437 -0.0799669011729016 0.735890291781448 0.230123815043086 2.74750476830378 0.0837573851364622 0.933310714265595 -8.61217301322757 11.74241015606 -0.733424646113471 0.463928811583081 MUC12 other 1 1 1 0.0837573851364622 -0.733424646113471 0.485472722175182 21.7324575084439 19.9305709980488 1.09040817298067 0.276535203912289 -6.05582839840196 60.4349548719053 -0.10020406917218 0.920258948059966 LINC01602 other 1 1 1 1.09040817298067 -0.10020406917218 2.60563700479563e-06 234.545097511449 74.1627061850532 3.16257468984755 0.00174095922428148 -247.896245124882 120.382915793386 -2.05923110842695 0.0404239593740814 SNX2 other 0.0223928444192136 1 1 3.16257468984755 -2.05923110842695 0.547407327165082 10.2079553523246 23.8302452143528 0.428361322365933 0.668727086592598 -91.7447147036272 103.745615790855 -0.884323776038679 0.37730246781979 SAP25 other 1 1 1 0.428361322365933 -0.884323776038679 9.81558740390018e-06 44.1122257154896 9.43232868172119 4.67670574298096 4.58960097655357e-06 17.4261119934316 24.5353049481545 0.71024639922979 0.478157612166795 NT5M other 0.0804976322993854 1 0.0484157007016636 4.67670574298096 0.71024639922979 4.25208020132958e-05 100.951956563938 33.6701433332314 2.99826334461431 0.00296639120892466 -203.489489249461 90.1193035149638 -2.25800113086397 0.0247383458379599 SARNP essential 0.32796294592855 1 1 2.99826334461431 -2.25800113086397 0.509776991711494 1.6945997338841 2.07807502748497 0.815466097937292 0.415516438168938 -6.37004756325218 7.77277144417016 -0.819533625683789 0.413196916764193 LINC01460 other 1 1 1 0.815466097937292 -0.819533625683789 1.81975125931587e-07 851.009828512281 493.35189684327 1.72495501478255 0.0856673321514781 -2934.16034038789 862.632280875254 -3.40140336205689 0.000770724412362899 ADGRG1 other 0.00171329581064589 1 1 1.72495501478255 -3.40140336205689 3.5774077731918e-21 1140.8175266987 162.57236082208 7.01729076781516 1.79992855388708e-11 -539.312727087508 253.141414864574 -2.13048002191199 0.034029242882265 IPO7 essential 5.30708443153004e-17 1 2.45924238317592e-07 7.01729076781516 -2.13048002191199 2.92982858815038e-10 317.219418937671 57.1234977739457 5.55322120142222 6.64864162879986e-08 -304.829578670761 154.595776899845 -1.97178464239839 0.0496436586355109 PRR13 other 3.25826237288204e-06 1 0.000792983487066959 5.55322120142222 -1.97178464239839 0.00224856744523635 42.3778979605916 18.852339071947 2.24788541086933 0.025406008617744 -179.321158074395 81.9606963134336 -2.18789207681492 0.0295510378063318 TECPR1 other 1 1 1 2.24788541086933 -2.18789207681492 0.105720849903967 69.1564715989339 36.2702828080456 1.90669788721894 0.0576133328503761 24.106949925011 65.1541856364009 0.369998484203948 0.711671546570572 MT1H other 1 1 1 1.90669788721894 0.369998484203948 0.68021050079185 14.8540874916881 27.6084709656659 0.538026445222583 0.590998750224822 43.5576126893526 49.5945248608638 0.878274624296781 0.380569855572225 MT1A other 1 1 1 0.538026445222583 0.878274624296781 0.0168826136595591 54.3891402714931 28.952417352928 1.87856991727127 0.0613806471495171 -67.3604826546007 54.2278446650129 -1.24217517901944 0.215249779151375 C15orf59 other 1 1 1 1.87856991727127 -1.24217517901944 0.531404157335001 10.9038567011758 41.3450661915814 0.263728122979667 0.792189113063155 77.0454737393886 74.2702815980808 1.03736611847422 0.300486581716876 MT1M other 1 1 1 0.263728122979667 1.03736611847422 0.00346961777133331 -195.870258578371 103.881643849445 -1.8855136607411 0.0604380731824488 -555.362807082269 163.449920167438 -3.39775514428735 0.000782219300018384 CFI other 1 1 1 -1.8855136607411 -3.39775514428735 0.117566173795032 21.1058399527242 79.8971964071101 0.264162460034029 0.791860833521111 -748.365034004004 374.921007820843 -1.99606055247139 0.0469544838578005 SAMD9 other 1 1 1 0.264162460034029 -1.99606055247139 0.848700599305387 4424.53779488978 9211.54033554803 0.480325508407661 0.631382019287103 -3369.84433811064 24816.6222614689 -0.135789806630646 0.892087889446166 KRT6A other 1 1 1 0.480325508407661 -0.135789806630646 1.1737819618499e-10 49.4424471058979 13.6524715757138 3.62150155975058 0.000350443602106509 -70.372845267015 24.4530397001455 -2.87787719359063 0.00432730635347634 CNEP1R1 other 1.33059923195305e-06 1 1 3.62150155975058 -2.87787719359063 0.30054650529993 1031.40060068097 663.700475203687 1.55401516077631 0.121343539921579 915.954208483876 1787.47551863437 0.512428952975906 0.6087666804032 KRT81 other 1 1 1 1.55401516077631 0.512428952975906 0.0168061711739252 -25.7261448424053 17.6118393404489 -1.46073015686217 0.145265248898508 65.5575495591477 41.1331002757791 1.59379062408653 0.112166000318011 EXOC3L4 other 1 1 1 -1.46073015686217 1.59379062408653 0.314279027515469 5.2049944506104 7.31116609274599 0.711923978279567 0.477122015509654 -9.4279588336192 11.4640335943816 -0.822394557378105 0.411572726264332 ATP6AP1L other 1 1 1 0.711923978279567 -0.822394557378105 2.59605265109659e-20 730.460796996464 85.8843480416757 8.50516786413754 1.27693468486355e-15 -300.393923335534 188.658779432821 -1.59226050459264 0.112500565059049 CCDC85C other 3.80996687074936e-16 1 1.88220172548888e-11 8.50516786413754 -1.59226050459264 0.331591167938145 15.2094517835698 19.7000719839657 0.772050568949651 0.440754742078942 -33.4561654062125 39.0063014263822 -0.857711810214956 0.391806735349659 C2CD4B other 1 1 1 0.772050568949651 -0.857711810214956 1.34465904858636e-05 18.4862704004735 27.4667932555007 0.673040723338584 0.501492801990886 242.539756470145 53.6794499822552 4.51829809266528 9.303957791228e-06 RGL3 other 0.10890393634501 0.143243734153746 1 0.673040723338584 4.51829809266528 2.32595423767467e-12 494.727637489639 169.715202666114 2.91504608731448 0.00385234825999533 -815.287804157987 246.279068610824 -3.3104226386625 0.00105742216589082 NAP1L4 other 2.82649958962226e-08 1 1 2.91504608731448 -3.3104226386625 3.11944904055874e-08 241.747565770995 40.146074398534 6.02169874372132 5.57563633153589e-09 116.228868239552 116.864192234212 0.994563570050723 0.320832511240772 TMEM256 other 0.000308638288072882 1 6.99686603244439e-05 6.02169874372132 0.994563570050723 0.0114312426741106 3.02116465109465 1.37916061887973 2.19058216261185 0.0293667594402121 -2.66911801742808 2.91501445063817 -0.915644866475276 0.360698391643727 CHKB-AS1 other 1 1 1 2.19058216261185 -0.915644866475276 0.0950231595981627 15.7562585129417 49.0261615300889 0.321384706067016 0.748174133011522 -185.991490100173 103.458243369772 -1.79774452032225 0.0733644205763522 CPT1B other 1 1 1 0.321384706067016 -1.79774452032225 1.48170545290089e-20 1043.98000377875 142.126763879263 7.34541458120875 2.39372366220698e-12 -660.877222500332 229.256673861161 -2.88269567629059 0.00425765277819493 HMGN1 other 2.18077408557953e-16 1 3.34403195610316e-08 7.34541458120875 -2.88269567629059 0.000448519957238465 13.4057915043848 15.1130053708481 0.887036772331442 0.375863417508211 -100.744874078986 32.0963800233898 -3.13882356843885 0.00188805329665125 DENND6B other 1 1 1 0.887036772331442 -3.13882356843885 2.00882103050782e-54 3079.71483344697 155.622268953908 19.7896795500335 4.50977351834149e-54 1281.82942342005 500.176103846442 2.56275622438289 0.0109395863025028 EIF3CL essential 3.20045366580506e-50 1 7.18587312412533e-50 19.7896795500335 2.56275622438289 0.0993935820899305 5.32303479477333 2.47199666453276 2.1533341331508 0.0322414732114199 4.63336235378157 7.69778997039881 0.60190812838474 0.547776438704654 LINC01446 other 1 1 1 2.1533341331508 0.60190812838474 5.91610358059475e-23 227.396313693751 23.58896720205 9.6399436120285 4.40849565360783e-19 -31.358509380094 50.621858222888 -0.619465789699433 0.536133863833321 LCMT1 other 8.92858352383359e-19 1 6.71369803087936e-15 9.6399436120285 -0.619465789699433 6.03179328620763e-05 7.0722350708689 2.87289398021817 2.46171112458937 0.0144601152947534 -14.9721221295921 6.2278086501349 -2.40407548958137 0.0168951274291317 LINC00898 other 0.458393374667639 1 1 2.46171112458937 -2.40407548958137 0.0435530012973669 16.5605052474525 8.69451378824781 1.90470745699857 0.0578728774641169 56.1466479035619 30.3932729057777 1.8473379973793 0.0657840162446036 MFSD2B other 1 1 1 1.90470745699857 1.8473379973793 1.02692818377842e-09 31.8727166349835 6.33093995002135 5.03443673239642 8.76924226994788e-07 -28.7962397232126 14.033562844214 -2.05195501975361 0.0411383609109084 CDPF1 other 1.10805551029692e-05 1 0.00976279741913297 5.03443673239642 -2.05195501975361 2.77450263098552e-17 111.048360763493 14.5604025021867 7.62673701821192 4.01588714461458e-13 -39.1448024053162 28.4517826869064 -1.37582951606512 0.170002091726815 LIN52 other 3.87875467811776e-13 1 5.71219787449978e-09 7.62673701821192 -1.37582951606512 2.46412592894808e-05 20.4792624534748 9.33513451468542 2.19378332698455 0.0291066412630431 -32.9891079359339 13.2362702513441 -2.49232656250608 0.013293128965326 SMIM11A other 0.194813795942635 1 1 2.19378332698455 -2.49232656250608 0.181460055315109 4.80370215596969 5.20843101494161 0.922293516452295 0.35720195789355 -13.7122929626861 11.8878542890177 -1.15347081393434 0.249741040842156 CYP2D7 other 1 1 1 0.922293516452295 -1.15347081393434 1.30200172008138e-15 83.6925781679377 9.70876510817473 8.62031136147985 6.07918870416049e-16 -18.0370741858443 58.2649364985483 -0.309569962138271 0.757130367267955 ETFRF1 other 1.74858831006929e-11 1 8.99902303876877e-12 8.62031136147985 -0.309569962138271 0.0290976592805318 20.7649781833934 8.22085947355246 2.52588895968809 0.0121087328296252 38.5529376078529 24.396857760345 1.58024193060294 0.115213617771075 C17orf107 other 1 1 1 2.52588895968809 1.58024193060294 6.52826901719699e-10 83.4625609846054 37.2824062101558 2.23865810897876 0.0260023605856989 -236.400016859675 53.4138190756076 -4.42582127529674 1.40116729440637e-05 ITSN1 other 7.13082824748427e-06 0.214925051288993 1 2.23865810897876 -4.42582127529674 0.000114760747791508 93.668507564723 107.922756523757 0.867921748682389 0.386205080551529 -675.583552299142 211.018862242894 -3.20153158404157 0.00152991474771769 ITPRIPL2 other 0.843733483403452 1 1 0.867921748682389 -3.20153158404157 0.00103243449702081 13.6452896388087 22.4194225486837 0.608636980242379 0.543273028765021 -118.446870919975 41.5986395625781 -2.84737366811701 0.00474430066232763 DENND1C other 1 1 1 0.608636980242379 -2.84737366811701 2.61023809833423e-09 57.5497591795326 19.0861206901754 3.01526748749716 0.00281575357043778 -96.5329760297772 27.311608134658 -3.53450355445303 0.000481652815970142 CRYZL1 other 2.75484528898195e-05 1 1 3.01526748749716 -3.53450355445303 6.61567405992399e-11 35.9172771718022 6.2995857650537 5.70152999123364 3.08841982820141e-08 -38.2042765995927 16.9091262492957 -2.2593879799782 0.0246508523042151 RP9P other 7.58619344451484e-07 1 0.000374409135772857 5.70152999123364 -2.2593879799782 1.07773240594965e-25 262.760869389528 22.0331415905676 11.9257105624019 2.70556021719336e-26 19.6760316802856 141.245741850721 0.139303538800347 0.889321557764154 C5orf51 other 1.65809130655354e-21 1 4.23907174829855e-22 11.9257105624019 0.139303538800347 5.23190585160537e-08 105.232465707054 23.0707793735327 4.56128785262362 7.72062226657558e-06 -47.8234947308015 41.6202316845416 -1.14904441410315 0.251554540673706 CATSPER2P1 other 0.000509953863355976 1 0.0799702054371899 4.56128785262362 -1.14904441410315 0.000163111122896226 7.21527926963712 1.76603880194296 4.08557233380095 5.78989321626521e-05 15.9337284277139 7.64195734280492 2.08503236971296 0.0379988536140662 LOH12CR2 other 1 1 0.556235041286598 4.08557233380095 2.08503236971296 0.350916858325595 8.5717925528198 10.0729357293626 0.85097262437931 0.395535835813322 42.3571741378919 30.666469192691 1.38122109434063 0.168348805707653 CYS1 other 1 1 1 0.85097262437931 1.38122109434063 3.43196805470302e-36 158.085607967046 11.3227626375192 13.9617523592002 1.15889353706715e-33 -4.76314006938151 39.8043456309718 -0.119663820466761 0.904839115084447 PLPP6 other 5.43005985615112e-32 1 1.83510791594583e-29 13.9617523592002 -0.119663820466761 0.783182271120643 1.53366895538031 2.34201140355202 0.654851190329074 0.513116951635495 3.84010610021134 10.4727501463719 0.366675996900553 0.714145788949198 KLRC2 other 1 1 1 0.654851190329074 0.366675996900553 0.890322702234263 -2.73177839116113 11.5851593948085 -0.235799810608155 0.813769464134872 -38.8073438858987 87.8595809284768 -0.44169734792487 0.65906708527613 GMNC other 1 1 1 -0.235799810608155 -0.44169734792487 1.33413390228178e-13 7.84247370271714 0.999549097254839 7.84601149083693 1.01725165923914e-13 -4.62442515989808 6.47560576700055 -0.714130125626854 0.475765909777568 TTC23L other 1.69435005589786e-09 1 1.45955268067632e-09 7.84601149083693 -0.714130125626854 0.0144060545166433 4.04481855175874 1.74010816423337 2.32446386661299 0.02083993014407 -3.88190804320736 4.54798805200885 -0.853544028439723 0.39411148873841 RFPL3S other 1 1 1 2.32446386661299 -0.853544028439723 0.0280796793639095 18.9874186122433 7.89153372070579 2.40604922746819 0.0167959915184304 4.48135314895482 12.1136908178665 0.369941186078916 0.711715252198763 C1QTNF9B other 1 1 1 2.40604922746819 0.369941186078916 0.000548652731542811 39.516644660983 10.2050180191898 3.8722758339745 0.000135219190747352 3.73685857415121 46.9262563827356 0.0796325737913759 0.936588258959731 C1RL-AS1 other 1 1 1 3.8722758339745 0.0796325737913759 1.57149505055677e-07 205.6011043524 39.5279100832871 5.20141601008477 3.88670775091491e-07 -140.777296879744 104.30844025937 -1.34962517443163 0.178254325217932 ZNF316 other 0.0014852199722812 1 0.004430846836043 5.20141601008477 -1.34962517443163 5.04436592823667e-10 12.556598930992 2.15260488045093 5.83321121540968 1.54553746153372e-08 0.768080172617069 3.98407402820812 0.192787625726553 0.847269692961264 SRRM2-AS1 other 5.54224484535363e-06 1 0.000190209295390955 5.83321121540968 0.192787625726553 0.253629841520018 -9.13860313311522 8.73999005093535 -1.04560795605679 0.296684227970333 -25.3892181924706 15.374645475468 -1.65136934266107 0.0998344088688207 ONECUT3 other 1 1 1 -1.04560795605679 -1.65136934266107 5.71508181151434e-05 22.1085690751678 9.8951042158498 2.23429370655386 0.026279386115225 -38.1208811705965 18.3140101886796 -2.08151468618053 0.0383254414734265 CEMP1 other 0.435317781583047 1 1 2.23429370655386 -2.08151468618053 1.50358013128038e-23 1110.03147301391 123.642188905822 8.9777727395252 4.75736351651493e-17 -203.700778193759 227.216163731227 -0.896506546227563 0.37077796445667 RNPS1 other 2.28032962709983e-19 1 7.12272465692615e-13 8.9777727395252 -0.896506546227563 0.0167923815894524 10.2765618338389 128.855915599387 0.0797523480861266 0.936492868536262 -607.169124909098 252.550570431147 -2.40414869731855 0.0168792011008151 NYNRIN other 1 1 1 0.0797523480861266 -2.40414869731855 2.36430017370952e-31 127.902955748905 9.34219953817777 13.6908824550598 1.81558426577867e-32 17.3233381443696 101.706473321027 0.170326800042414 0.864886110420666 DNAJC19 other 3.71384271286291e-27 1 2.87170963318212e-28 13.6908824550598 0.170326800042414 3.18062884524437e-05 42.1162408559886 16.9278094082771 2.48799120076312 0.013452494141807 -54.6627033518942 27.6710752253998 -1.97544558375954 0.0492396557839307 DOK6 other 0.248534337967395 1 1 2.48799120076312 -1.97544558375954 2.96156194675553e-19 922.027117794682 155.554608754323 5.92735326312895 9.33369005748731e-09 -936.519054573075 284.739777174584 -3.2890348649773 0.00113828380840964 JPT2 other 4.28212241881381e-15 1 0.000116055102174797 5.92735326312895 -3.2890348649773 0.0103803181087922 -807.682409692169 320.296889875964 -2.52166797499953 0.0122515451261012 -1545.16818159839 567.233248907517 -2.72404374139626 0.0068664136057753 SERPINB11 other 1 1 1 -2.52166797499953 -2.72404374139626 0.0747929574494218 -710.800255152773 385.78323429523 -1.84248612164627 0.0664923422344438 -1422.9049997655 683.207000380414 -2.08268504124404 0.0382142155376925 SERPINB4 other 1 1 1 -1.84248612164627 -2.08268504124404 0.0305060147185865 343.842414258598 435.01531761816 0.790414498830152 0.429974321396367 -1411.19407716899 770.395091980572 -1.83177968273528 0.0680777399979085 SERPINB5 other 1 1 1 0.790414498830152 -1.83177968273528 0.132156502755391 33.6205896949804 17.2982846088962 1.9435794042659 0.0530047746788233 -30.8750876571975 99.5760034783624 -0.310065543692026 0.756754814057626 ZDHHC11B other 1 1 1 1.9435794042659 -0.310065543692026 3.57134904863125e-06 133.959497343924 47.0095169139768 2.84962505760394 0.00471309020592255 -183.52129582554 86.7852629783765 -2.11465967293624 0.0353719927414167 HERC2P9 other 0.030352895564317 1 1 2.84962505760394 -2.11465967293624 0.34084347186916 -270.469395284122 205.404415388821 -1.31676524466203 0.189067935560522 -69.241646446227 374.824473492801 -0.1847308576225 0.853583053560522 HBA1 other 1 1 1 -1.31676524466203 -0.1847308576225 0.367212267948484 -52.3247873802781 37.0043661294381 -1.41401658380663 0.158513324740044 -57.2950059418129 67.9793330983099 -0.842829773851331 0.40007242233475 ATP10A other 1 1 1 -1.41401658380663 -0.842829773851331 1.95338290728795e-11 44.0492002148936 5.99341722932175 7.34959682089052 2.37007811188314e-12 2.74998007036034 38.4176370425487 0.0715811872373788 0.942988205185291 ANKUB1 other 2.29190416512095e-07 1 3.31147313792312e-08 7.34959682089052 0.0715811872373788 1.73619930460591e-09 5.53076519899187 1.13713688819593 4.8637637705751 1.98905662845558e-06 -13.009693189208 4.46225869340633 -2.91549506272055 0.00385850503577778 TSSK2 other 1.85217741815358e-05 1 0.0215991659283991 4.8637637705751 -2.91549506272055 0.0208055746543378 13.1567114063643 4.72173818061247 2.78641273681501 0.00571029538956717 16.3019425179707 24.2935633669513 0.671039578333232 0.502773240736188 FOXL2NB other 1 1 1 2.78641273681501 0.671039578333232 0.324103332719789 136.392617159289 94.3619655010701 1.44541941697624 0.149487031017361 173.655092553538 181.684370383886 0.955806447118251 0.340015633969253 HCP5 other 1 1 1 1.44541941697624 0.955806447118251 0.683118072817667 1.14354577606107 2.28247447219523 0.501011419839118 0.616766799064614 -2.04014890115366 4.38336422267897 -0.465429929504417 0.641994669648473 HCG27 other 1 1 1 0.501011419839118 -0.465429929504417 0.10033591364464 43.7485624818144 23.252068967532 1.88149117151264 0.0609769563447301 -77.5683191775318 107.50430813772 -0.721536843697108 0.471201333225519 COL6A6 other 1 1 1 1.88149117151264 -0.721536843697108 8.99927854143852e-12 291.933386036688 47.8148230195026 6.10549966728131 3.56766594522607e-09 -157.97367731203 102.854849619994 -1.53588943929895 0.125740834780512 RAB12 other 1.0691142907229e-07 1 4.51488125368359e-05 6.10549966728131 -1.53588943929895 0.276916617887094 2.03506224493872 14.1160676504288 0.144166370928159 0.885477444229747 -43.9011518939731 31.0387148450446 -1.41439979435817 0.158405257984857 TMEM200C other 1 1 1 0.144166370928159 -1.41439979435817 0.321774230743918 -2098.59881363251 2001.20278155587 -1.04866874710264 0.295258086476616 -5256.44085613916 3778.73565524535 -1.39105810400963 0.165340469098898 HLA-A other 1 1 1 -1.04866874710264 -1.39105810400963 6.14942298077476e-09 365.943049311884 61.6662733212106 5.93424946251803 8.99310302847692e-09 -283.064637259637 241.068972816456 -1.17420601229821 0.241343333784892 HACD2 other 6.35050911224609e-05 1 0.000111910174086367 5.93424946251803 -1.17420601229821 0.00933875071257012 22.0491821170872 13.8436605088683 1.5927277401062 0.112378432259876 -121.489053660188 53.1092143942879 -2.28753249404597 0.0229297853380638 CFAP44 other 1 1 1 1.5927277401062 -2.28753249404597 4.32315749424246e-11 30.2246283081662 5.4732263072171 5.52226906245617 7.93205065262343e-08 -62.0035752176377 20.0151347958541 -3.0978345062398 0.00215739996558495 LNP1 other 4.99886701059255e-07 1 0.00094280354057082 5.52226906245617 -3.0978345062398 0.0357641013206081 -94.5088389960093 87.8231453142939 -1.07612678477626 0.283023084297694 -479.968597322194 184.625168235041 -2.59969213250037 0.00994824676535082 VGLL3 other 1 1 1 -1.07612678477626 -2.59969213250037 0.0464871130082959 93.4506194081214 37.7967962717081 2.47244816032388 0.0140287498628912 110.818823124571 98.1706189549533 1.12883899790243 0.259956734268165 PRSS50 other 1 1 1 2.47244816032388 1.12883899790243 3.16921716415069e-10 158.950867765196 41.2028832051551 3.85776080216902 0.000142830803784161 -455.393234950052 112.70308563355 -4.04064566990425 6.93551688161205e-05 ANKRD28 other 3.51814797392368e-06 1 1 3.85776080216902 -4.04064566990425 0.572305770033355 14.7094837276889 14.2150116603309 1.03478520307781 0.301684986688985 21.7517387291057 38.8826109197072 0.559420733705953 0.576333270264692 COLQ other 1 1 1 1.03478520307781 0.559420733705953 1.04255748912945e-28 107.968195651577 9.10088007740178 11.8634895453321 1.84993586036491e-26 -13.3254199453477 24.8938226385029 -0.535290225967042 0.592884949614406 METTL6 other 1.6244088238126e-24 1 2.90014444829407e-22 11.8634895453321 -0.535290225967042 5.06264722273236e-12 150.694009696057 20.4968198482776 7.35206782376634 2.31497511983534e-12 32.6675779779956 57.6582186264124 0.566572793198142 0.571473385752994 THUMPD3-AS1 other 6.06555763755564e-08 1 3.23471473494592e-08 7.35206782376634 0.566572793198142 0.443677656629734 20.5384671876684 20.1428257093403 1.01964180617145 0.308857251212856 -24.2322362863331 63.382227497431 -0.382319101791039 0.702540655280744 XKR4 other 1 1 1 1.01964180617145 -0.382319101791039 0.0309139936404709 0.312522655872392 1.95724353568631 0.159674894909184 0.873257452249979 -7.48094964786303 3.48413053669556 -2.14714964582187 0.0326785967289181 SNORA25 other 1 1 1 0.159674894909184 -2.14714964582187 6.18662512207853e-07 7.51300447075881 2.10189425901589 3.57439697003427 0.000416217771063378 -5.95795501622593 3.74162634297546 -1.59234366825843 0.112486261576796 SNORA18 other 0.00560570102311536 1 1 3.57439697003427 -1.59234366825843 0.000429393765621734 4.35098477525374 2.24270559479334 1.94006060597297 0.0534212741070298 -7.58623040806465 3.99228757442159 -1.90022143110865 0.0584772190195607 SNORA8 other 1 1 1 1.94006060597297 -1.90022143110865 6.61196488936164e-20 7.35887527748085 0.77810262348487 9.45746107952037 1.52229632883431e-18 -0.873107877259778 2.126666036571 -0.410552415022136 0.681722798019992 SNORA7A other 9.65479113144587e-16 1 2.31008467900607e-14 9.45746107952037 -0.410552415022136 8.16269636901234e-15 7.38771851470757 0.901305759748244 8.19668401627782 1.05337903516618e-14 -0.0944965146539218 3.12721877770058 -0.0302174300460694 0.975916307134668 MIR130B other 1.07282318377929e-10 1 1.53445724052657e-10 8.19668401627782 -0.0302174300460694 1.11117476940987e-10 13.012151099565 2.31944519473135 5.61002740186414 5.03695768719261e-08 -2.51480399433819 4.12889335629945 -0.60907458181291 0.542990956361902 SNORA40 other 1.26128030271328e-06 1 0.000605089726962448 5.61002740186414 -0.60907458181291 0.0249387162738325 -414.555479861599 1036.08271402514 -0.400118131737829 0.689382411371106 -4454.19989250368 1728.99432161587 -2.57617959574378 0.0105159189296017 GPX3 other 1 1 1 -0.400118131737829 -2.57617959574378 0.888329110248034 8.64504370894111 83.9026305834406 0.103036622914268 0.918009551243953 74.3485017807345 158.277420259212 0.469735365025369 0.638919077932542 DIO2 other 1 1 1 0.103036622914268 0.469735365025369 0.000229752007536899 255.26533684667 85.4424360481352 2.98757091502941 0.00306868073482308 -350.01548214459 218.593539325837 -1.60121604336556 0.11048980633575 SELENOH other 1 1 1 2.98757091502941 -1.60121604336556 7.26274284649731e-08 47.0200117166076 8.21000828132316 5.72715764776666 2.88788807447567e-08 -38.3331093882435 27.8337994627227 -1.37721439861569 0.169663207563506 GNRHR2 other 0.00070158095897164 1 0.000350502975599112 5.72715764776666 -1.37721439861569 0.000142390470021492 10.6421242962401 3.54176188464359 3.00475431236141 0.00290583083355031 -3.70081537802 5.36309652724313 -0.690051980086657 0.490749842246629 AKR7L other 1 1 1 3.00475431236141 -0.690051980086657 1.59875816192504e-12 321.128657675532 42.8224610146844 7.49907058273491 9.19970607740113e-13 -149.708550067925 268.665146994314 -0.557231005743716 0.577829543653674 STK38L other 1.95656023856386e-08 1 1.29679056867046e-08 7.49907058273491 -0.557231005743716 0.00113485305174538 101.687838667726 50.2392788145684 2.02407042989317 0.0439366873212417 -295.358897478503 130.579178303231 -2.26191419885199 0.0244892655632181 SACM1L essential 1 1 1 2.02407042989317 -2.26191419885199 1.26407779146974e-07 451.871041748422 86.5657700220973 5.21997368744107 3.56562752008802e-07 -217.493234370756 257.969867825589 -0.843095498726233 0.399918545527191 TSN other 0.00120239079524602 1 0.00407658194371663 5.21997368744107 -0.843095498726233 2.03150640379757e-05 278.070179476726 75.3031443497157 3.69267687130485 0.000268510817768212 -308.587252908766 191.775349291377 -1.60910802169839 0.108761294385748 SLC48A1 other 0.16197200557478 1 1 3.69267687130485 -1.60910802169839 4.60386990746542e-09 6.4482756169536 1.33192253610752 4.84132931318841 2.18982376646628e-06 -3.64911480790205 2.77056634550868 -1.31710067647994 0.188938358809577 MIR762 other 4.78250005987507e-05 1 0.0236785643867999 4.84132931318841 -1.31710067647994 1.86031472051272e-06 17.2130157912173 6.09241824978063 2.82531748240316 0.00507331778673322 -25.0457710812002 11.434825248171 -2.19030641375181 0.0293510533430838 PRR22 other 0.016221944362871 1 1 2.82531748240316 -2.19030641375181 7.92295103173918e-20 37.7737918527959 3.75955561745616 10.0474087089992 2.04516909590622e-20 11.351892565571 16.4066861344031 0.691906486939327 0.489584086700725 TAS2R14 other 1.15572086699979e-15 1 3.13667584239137e-16 10.0474087089992 0.691906486939327 2.83166346658559e-16 29.4421029245487 3.48966372593863 8.43694557320978 1.92494838097681e-15 -17.5181811524679 12.9606479923285 -1.3516439272818 0.17760811469139 SNORD86 other 3.86635329727596e-12 1 2.83217655293117e-11 8.43694557320978 -1.3516439272818 0.0377916031535349 15.7408109828353 24.5319956246538 0.64164412971835 0.521644608820684 -109.041327937821 50.8356894992099 -2.14497588233785 0.0328405021819214 LINC01089 other 1 1 1 0.64164412971835 -2.14497588233785 0.181183120606361 5.62293867243321 3.38674986378176 1.66027575067338 0.0982041355436192 10.6187372565031 7.54050613342383 1.40822606183354 0.160397032855767 CTAGE1 other 1 1 1 1.66027575067338 1.40822606183354 1.1552833366797e-10 112.878956228253 19.209239894304 5.87628437404876 1.23247543905235e-08 -4.41524053784217 46.9288865945982 -0.0940836414037231 0.92511249523354 C17orf51 other 1.31009130379478e-06 1 0.000152383263284433 5.87628437404876 -0.0940836414037231 0.00430829487625663 33.0075339025614 11.0739190322756 2.9806551597821 0.00313852421803424 53.8556504269209 21.1712642170196 2.54380890412895 0.011522955253447 EWSAT1 other 1 1 1 2.9806551597821 2.54380890412895 0.000103441100672503 17.8367623904635 10.2700681134385 1.73677157672634 0.0835722535807404 -58.9272394550135 19.3539432403858 -3.04471490502516 0.00255993714237358 RNF208 other 0.765360703875852 1 1 1.73677157672634 -3.04471490502516 0.0457148394815028 15.7547425755414 6.50274053406392 2.42278505393409 0.0160553683564484 -5.98000691652616 17.933173101658 -0.333460614171693 0.739043525530906 MAP10 other 1 1 1 2.42278505393409 -0.333460614171693 0.0857861199221563 3.68221633478534 2.26091499454208 1.62863988415059 0.104604988613257 -12.2319859920962 9.59250190614006 -1.27516117398597 0.203394844638765 POU5F1B other 1 1 1 1.62863988415059 -1.27516117398597 0.525079038759827 -0.0455929062996361 4.04921928498508 -0.0112596782467917 0.991024612396534 13.7209943532733 13.0017166990809 1.05532174487722 0.292225093771989 PTTG3P other 1 1 1 -0.0112596782467917 1.05532174487722 8.37269699313858e-10 52.191244974794 14.5049248935075 3.59817409314233 0.000381086156553692 -119.829213958286 32.1761366408797 -3.72416413119166 0.000238562815525211 ZNF580 other 9.08939985575124e-06 1 1 3.59817409314233 -3.72416413119166 1.63083554549205e-05 25.8032452867599 8.05614931257544 3.20292540339113 0.00152404820112106 -44.3023266277805 20.5706050062208 -2.15367154317449 0.0321545372824219 ZNF611 other 0.131151794568471 1 1 3.20292540339113 -2.15367154317449 0.663032562684841 -9.05597526205369 24.6299937401301 -0.367680778062831 0.713398266956665 -49.6337149232109 54.723708071573 -0.906987422312376 0.365219207569572 KLK9 other 1 1 1 -0.367680778062831 -0.906987422312376 0.360046399045359 6.16854077145213 4.31686094993986 1.42894127074861 0.154172731790765 5.88419190044479 9.37865237407871 0.627402708379285 0.530923552451125 SYT3 other 1 1 1 1.42894127074861 0.627402708379285 6.39385207202445e-14 517.70902457582 101.777493429105 5.08667493306308 6.78385138884484e-07 -852.432233901027 211.2024570313 -4.03609051657339 7.06371060358784e-05 NUP62 other 8.20011528237136e-10 1 0.00760808933258949 5.08667493306308 -4.03609051657339 1.42425718471107e-05 10.1291040318566 2.44090675596791 4.14973001614723 4.45583514362021e-05 -13.3872059067529 6.87724675008477 -1.94659380319427 0.0526128640141802 SPHAR other 0.115208163671279 1 0.432795267499831 4.14973001614723 -1.94659380319427 0.00152099093267779 62.2371166241638 20.0488287743709 3.10427692931987 0.00211258479944376 -83.3296382191338 53.5365428491851 -1.55650017323452 0.120773701636565 DENND1B other 1 1 1 3.10427692931987 -1.55650017323452 3.35381092001566e-05 9.05359679647588 1.95779549445811 4.62438330362067 5.85064354812516e-06 1.8959441142738 6.14867431603805 0.308350063253223 0.758055511041482 C1orf220 other 0.26139602310602 1 0.0611977315133892 4.62438330362067 0.308350063253223 8.94180520688463e-08 414.891852982317 71.4633292837438 5.80566084928673 1.78311005063128e-08 -129.996302511745 241.404243616143 -0.538500486008244 0.590671977825006 SFT2D2 other 0.000858502717912994 1 0.000218662785508914 5.80566084928673 -0.538500486008244 6.66933091728589e-15 148.946494348127 22.1461674397068 6.72561041334289 1.03389435888128e-10 -127.599986535526 41.3689121655026 -3.08444142850659 0.00225013921034415 FGFR1OP other 8.79217894825799e-11 1 1.38107608459361e-06 6.72561041334289 -3.08444142850659 0.000524721511359201 5.18656564137186 2.09557188195917 2.47501204135402 0.0139329393105369 -8.50733261272357 3.93702638783923 -2.16085232219961 0.0315797361005859 LPAL2 other 1 1 1 2.47501204135402 -2.16085232219961 0.00828822788564079 6.86292106663619 2.19769304302708 3.12278417971569 0.00198412045248836 2.05259731977535 7.70179208871025 0.266509053494728 0.790048372896554 RPL31P11 other 1 1 1 3.12278417971569 0.266509053494728 2.44803608448007e-15 299.858905372729 43.8859601127871 6.83268417968049 5.45303701431024e-11 -259.561073879273 85.6996869773098 -3.02872837736263 0.00269185793372046 SCAF8 other 3.26470092226262e-11 1 7.34960328788735e-07 6.83268417968049 -3.02872837736263 0.0540828833601629 -1.44065429321335 8.2226508632622 -0.175205577516373 0.861048454416754 73.736951631046 30.6459691557087 2.40608972933428 0.0167916896120521 CFAP45 other 1 1 1 -0.175205577516373 2.40608972933428 0.873558821767492 -21.3184144584071 50.8415739360479 -0.419310670539486 0.675321281445882 49.5092864347585 180.911356718597 0.273665994953368 0.784549771759352 ACKR1 other 1 1 1 -0.419310670539486 0.273665994953368 0.0565992184239832 53.1635167292387 26.4741214287664 2.00813148312722 0.045659632216343 -9.57003615133966 54.6233496528591 -0.175200463028337 0.861057960024328 ZNF254 other 1 1 1 2.00813148312722 -0.175200463028337 6.35244089376643e-14 81.8697898081104 10.1476240399098 8.06787771069595 2.43920578118907e-14 -69.9194760039239 78.3051805210916 -0.89290996507046 0.372709454547997 TCTEX1D2 other 8.14891117852358e-10 1 3.5336774152086e-10 8.06787771069595 -0.89290996507046 1.3507516488808e-06 17.4505988889541 3.42659160013235 5.09269878799683 6.6925474294382e-07 -32.050151904507 31.5135811292942 -1.01702665187467 0.310064889457992 CRYGS other 0.0119109280398309 1 0.00751104598005849 5.09269878799683 -1.01702665187467 0.0679423541130646 -180.82613877443 140.307142661971 -1.28878783605535 0.198570945713247 -766.420099082597 333.645026573193 -2.29711231410927 0.0223749251628882 CRIP1 other 1 1 1 -1.28878783605535 -2.29711231410927 1.23806336631962e-06 24.309390198279 5.82549400569117 4.17293197358544 4.04572630364723e-05 -3.67076174853951 8.09343258565831 -0.453548195983514 0.650514356998323 FAM24B other 0.0109457182216318 1 0.394377400079531 4.17293197358544 -0.453548195983514 4.04418048507732e-12 344.45632101291 45.1729533208635 7.62527786408466 4.77160495878757e-13 23.0758102926017 293.123539815447 0.0787238387852794 0.937313782959325 TRIM59 other 4.86676679574205e-08 1 6.77138459701544e-09 7.62527786408466 0.0787238387852794 1.131835160108e-09 440.054497567983 65.9407198183786 6.67348640991532 1.44568815544343e-10 135.49420463766 261.087563039242 0.518960777221301 0.604219576900656 MLLT11 other 1.2187601004043e-05 1 1.9231989531864e-06 6.67348640991532 0.518960777221301 0.0453599637688862 -1.34261153492238 5.21336773866058 -0.25753248230813 0.796961754480817 -31.2062049927275 13.1494453271869 -2.37319553914625 0.0183275619101904 ASIC3 other 1 1 1 -0.25753248230813 -2.37319553914625 0.0966453596367586 -27.8770862708203 17.8699777580354 -1.55999557740273 0.119919389430338 -91.2186820548665 45.186316056386 -2.01872358749137 0.0444935090848839 GIMAP1 other 1 1 1 -1.55999557740273 -2.01872358749137 0.022333315068837 22.8854178713234 9.76825392427329 2.34283609422305 0.0198587432959714 -17.6067020675122 24.5811561727182 -0.716268264348497 0.474440221035634 CFAP206 other 1 1 1 2.34283609422305 -0.716268264348497 0.116008501214358 1.56677676079511 4.26283737431721 0.367543169775757 0.713500770316614 -14.0970079584649 7.99878239820121 -1.76239423160643 0.0791299823844366 CCDC183 other 1 1 1 0.367543169775757 -1.76239423160643 0.000131405173752152 105.194876629603 34.2176774734841 3.07428453351692 0.00232962596593129 -147.072746722552 90.1748065327721 -1.6309737983092 0.104079246731652 ARHGEF35 other 0.959520578738212 1 1 3.07428453351692 -1.6309737983092 7.06831030606722e-06 35.2854464578235 9.77601017323803 3.60939133987585 0.000365253695897273 -33.1422170402204 18.4130869970213 -1.79992724987298 0.07298014380915 DNLZ essential 0.0585750875063791 1 1 3.60939133987585 -1.79992724987298 0.775979835439861 6.85215384378584 22.1134729643504 0.309863306176842 0.756903928772204 -22.3614125856815 49.3078384327315 -0.453506243559799 0.650548521765968 TCL1B other 1 1 1 0.309863306176842 -0.453506243559799 7.73154832546856e-13 320.296051836635 46.0808911974327 6.95073475172893 2.67255508417556e-11 -159.540065806596 98.1351336222619 -1.62571812884763 0.105163420937987 SUPT4H1 other 9.57011051726499e-09 1 3.63333863693667e-07 6.95073475172893 -1.62571812884763 2.90924552500899e-20 409.380431856927 128.363643310923 3.18922415489037 0.00159281072655317 -1030.11554066852 188.517103660441 -5.46430812200454 1.04732208594903e-07 NRAS og 4.26582671332068e-16 0.00165466416359088 1 3.18922415489037 -5.46430812200454 0.00322340246565879 -2.95599330668272 3.2957991606779 -0.896897281227146 0.370566862479261 -18.2049243888959 5.41355995776251 -3.3628378610256 0.000882275947487656 LTC4S other 1 1 1 -0.896897281227146 -3.3628378610256 4.45544890580952e-06 62.7897412076415 14.6952679521312 4.27278641071226 2.69102231323162e-05 -136.867138941787 66.7909022755157 -2.04918835168903 0.0414246350613594 ANKRD39 other 0.0376084442139382 1 0.266734131687519 4.27278641071226 -2.04918835168903 1.15136509150741e-11 180.920814019372 37.490531991265 4.82577345292207 2.33998562675892e-06 -214.801299198411 76.9189819088895 -2.79256555232157 0.00560445153125746 QTRT1 other 1.36252544928987e-07 1 0.025264824812116 4.82577345292207 -2.79256555232157 6.10996570463214e-14 152.070257311632 29.1583642894919 5.21532195022459 3.63924741339136e-07 -95.0104081609957 41.8071077113977 -2.27258983847604 0.0238313804544863 CHUK other 7.84152998532489e-10 1 0.00415638447083427 5.21532195022459 -2.27258983847604 8.83759814407569e-15 435.328780960846 84.574365090455 5.14728996777271 5.07195709421284e-07 -535.436704513316 141.606683482564 -3.78115418951425 0.000191921895268704 MXD3 other 1.16046501229858e-10 1 0.00573131151646051 5.14728996777271 -3.78115418951425 0.285288079203226 588.457846542469 388.919412123778 1.51305856225861 0.13142156527012 332.041132512363 579.062597662094 0.573411465104024 0.566838171236795 GSTM2 other 1 1 1 1.51305856225861 0.573411465104024 1.36983339223068e-28 161.072268859574 20.1086904640975 8.01008246395539 3.44925048351946e-14 -160.781411908033 36.4470983683587 -4.4113638425498 1.48535647592027e-05 COG8 essential 2.13337852506007e-24 0.227675440629058 4.98451187373397e-10 8.01008246395539 -4.4113638425498 1.4494620556339e-17 281.639513778075 32.3481552939019 8.70650926518731 3.04329722323412e-16 57.2122594558042 50.7481302999632 1.12737669580402 0.260573136457116 ARHGAP19 other 2.03779870401571e-13 1 4.5223396737259e-12 8.70650926518731 1.12737669580402 0.154446313611128 16.4620837731315 16.0246542066464 1.02729728584744 0.305199937953437 -23.5772886890432 28.8147718309035 -0.818236175091169 0.413943876198485 LCAT other 1 1 1 1.02729728584744 -0.818236175091169 0.236560851812353 -47.0773638820514 28.4963978215687 -1.65204613498268 0.0997006348315998 -73.889590828499 82.9063540792868 -0.891241589973133 0.373602003973677 PTPRCAP other 1 1 1 -1.65204613498268 -0.891241589973133 1.49076287622928e-06 19.3222044515525 8.76126677095979 2.2054121803023 0.028264886821128 -34.6270291883248 13.768445503236 -2.51495560484199 0.0124838910860288 HNRNPA1P33 other 0.0130888980532931 1 1 2.2054121803023 -2.51495560484199 0.00986126553340425 10.3502285202795 4.26552796548275 2.42648239656029 0.0158962161504497 -24.0405424754329 18.8076735451978 -1.27823052743125 0.202257838109227 PVRIG other 1 1 1 2.42648239656029 -1.27823052743125 0.000796293917220259 28.3891309904769 7.43612640371974 3.81773109401098 0.000166833018075503 37.0759110725389 32.7875561885241 1.13079214746465 0.2591386550351 GPC2 other 1 1 1 3.81773109401098 1.13079214746465 8.43797531798794e-14 190.44840185661 29.3758312222349 6.48316639675057 4.34512181917365e-10 -131.202924043559 65.3169143669005 -2.00871283212433 0.0455780926896673 KRT222 other 1.07837324563886e-09 1 5.68646092475255e-06 6.48316639675057 -2.00871283212433 0.043954740386611 33.6586149553963 45.8660818929533 0.733845437985133 0.46367734736428 -232.750965454027 112.097662940405 -2.07632308603761 0.0388066373782291 SIPA1 other 1 1 1 0.733845437985133 -2.07632308603761 0.21322207527184 87.7682152792124 53.3999610876315 1.64360073474925 0.101495900732108 -18.0244378712595 160.748600023157 -0.112128117250558 0.910810384209238 ERV3-1 other 1 1 1 1.64360073474925 -0.112128117250558 1.20284171434896e-10 165.995306696663 32.7729794339327 5.0650050609922 7.54431220405914e-07 -114.660206190637 60.1696392896177 -1.90561564842921 0.0577543317578352 SYNJ2BP other 1.36281966235737e-06 1 0.00843378661291772 5.0650050609922 -1.90561564842921 2.35222197322301e-09 312.673287721414 56.8443842604318 5.50051323080404 8.78527481511528e-08 -227.311724029103 131.355474252835 -1.73050819025304 0.0846820846015656 ARL2 essential 2.49194395843246e-05 1 0.00104167003482822 5.50051323080404 -1.73050819025304 0.402111045182601 1.58235973540865 2.14431557194501 0.737932306285198 0.461191745583385 -2.3575493405938 3.86494768557015 -0.609982212539578 0.542382845857319 GBP7 other 1 1 1 0.737932306285198 -0.609982212539578 8.17748997605661e-13 283.432420207389 40.2604352762565 7.03997406542057 1.56863766190586e-11 38.8294869908201 72.8650467237901 0.532895932092259 0.594540722863372 RBMXL1 other 1.01147373513844e-08 1 2.14668064031816e-07 7.03997406542057 0.532895932092259 8.54890400838911e-14 127.480022374169 35.0179989566725 3.64041424902374 0.000326168988079919 -271.297184262215 57.5371086472408 -4.71516888214759 3.87537593273549e-06 SRA1 other 1.09220797611179e-09 0.0601109560926601 1 3.64041424902374 -4.71516888214759 0.100849839090397 50.2875262789065 31.3567668910057 1.60372166090027 0.109935924220295 -62.9169025928528 75.306475001346 -0.835477992984378 0.404181908769502 TMEM110 other 1 1 1 1.60372166090027 -0.835477992984378 0.584132332203753 4.62661515588631 4.74634704014287 0.974773887529946 0.330535363127481 2.2227152847511 7.38134826397966 0.301125919718184 0.763547699232487 KRT8P41 other 1 1 1 0.974773887529946 0.301125919718184 3.03073712999561e-13 288.949784245144 49.2631649141315 5.86543281879677 1.30612658793266e-08 -47.6549049154122 77.072232995603 -0.618314833542333 0.536889061023531 DNAJC9 essential 3.80145358215349e-09 1 0.00016137193993908 5.86543281879677 -0.618314833542333 4.51626708773347e-12 139.319972340932 20.0341039323094 6.95414044030431 2.78293295766305e-11 -83.2186910995303 75.0321379046791 -1.10910728953574 0.268393212115225 C8orf82 other 5.41906887857139e-08 1 3.77950124980219e-07 6.95414044030431 -1.10910728953574 1.79683057049655e-19 1331.04774670588 183.664682263029 7.24716222142083 4.37348843337856e-12 -743.619065961937 294.272589885492 -2.52697360039987 0.0120701784603489 VDAC1 other 2.60648242556229e-15 1 6.06908989899943e-08 7.24716222142083 -2.52697360039987 9.97367016824008e-19 97.7388399836896 13.2955264703388 7.35125759793995 2.30801792738987e-12 -65.0985621121043 24.4948807355485 -2.65763948046618 0.0083346312361432 ZBTB9 other 1.43002482872226e-14 1 3.2252242517346e-08 7.35125759793995 -2.65763948046618 1.99701576285751e-09 334.881073753624 70.6864048026133 4.73755985594055 3.48865144827867e-06 -453.68088007651 180.842121581332 -2.50871243994155 0.0126992974614594 TMX2 essential 2.12322715907011e-05 1 0.0371401833183747 4.73755985594055 -2.50871243994155 3.62033158785216e-05 243.296662914251 107.292059393467 2.26761108221457 0.0241493582450363 -559.518791101104 199.396060462523 -2.80606743083706 0.0053827788846814 HEXA other 0.281263561060234 1 1 2.26761108221457 -2.80606743083706 1.43459585886412e-11 410.806540481261 74.0728235891455 5.54598192124891 6.96226889421923e-08 -304.989316144065 158.58894036613 -1.92314366588202 0.0555136201234825 NDUFS3 other 1.69282311345966e-07 1 0.000829415093368337 5.54598192124891 -1.92314366588202 4.84104588389129e-45 879.852245119439 53.2994861485897 16.5077059592388 6.88951339688129e-43 -241.332560706402 210.575470650659 -1.14606207437508 0.252776724565952 LEPROT other 7.69919937374071e-41 1 1.09557042037206e-38 16.5077059592388 -1.14606207437508 0.616873309649255 182.88437725509 188.788810342066 0.968724666063217 0.333540016686257 -123.712185071692 723.430572413501 -0.171007681717079 0.864344402245017 LBH other 1 1 1 0.968724666063217 -0.171007681717079 2.70328235495371e-05 10.0251766450525 5.27376683998035 1.90095181475445 0.0583730970838534 -23.7630630106714 9.33106233138631 -2.5466621234263 0.0114314159098049 ADAT3 essential 0.212856452629055 1 1 1.90095181475445 -2.5466621234263 8.04514533769045e-07 1945.22246064688 359.015484552061 5.41821326473957 1.32268212434223e-07 732.560737376111 1376.97200623787 0.532008446110388 0.595152818549868 PPP1CB essential 0.0072148863388408 1 0.00155362242325239 5.41821326473957 0.532008446110388 0.216538623999807 80.1025170278953 50.515857054446 1.58569054745643 0.113971381898387 -1.75361687199166 96.4810025744865 -0.0181757737295258 0.985511954452216 GPSM3 other 1 1 1 1.58569054745643 -0.0181757737295258 0.436100684377985 -12.9245521562846 16.3091875755716 -0.792470630213572 0.428800557364058 -42.0415496814281 32.9334346876154 -1.2765613450345 0.202883194722062 LAT other 1 1 1 -0.792470630213572 -1.2765613450345 1.80950247512407e-08 193.76907694261 34.3859256419362 5.63512755074112 4.3536399991863e-08 -47.2074269228593 82.0354692503868 -0.575451415762295 0.565460040127789 NCKIPSD other 0.000181475003230193 1 0.000524439474301982 5.63512755074112 -0.575451415762295 9.5625952716058e-14 630.909475264494 97.0408532655357 6.50148317985332 3.93353608726383e-10 -351.671515547694 186.060253941623 -1.89009478433816 0.0598364926197902 ATF6B other 1.2196134009406e-09 1 5.15607910318543e-06 6.50148317985332 -1.89009478433816 0.132171732093347 12.3871583819532 24.25267301751 0.510754355736784 0.609935839520021 -101.323553202165 59.7766782811637 -1.69503485499114 0.0912090404224106 TREX1 other 1 1 1 0.510754355736784 -1.69503485499114 7.6383461642812e-05 5.30002540973195 1.74829537301966 3.03153888726349 0.00267693049925529 -5.49428281031634 3.60453466084811 -1.52426965677272 0.128647495989413 SEC14L1P1 other 0.573868947322446 1 1 3.03153888726349 -1.52426965677272 0.278782364934306 25.8864856879036 39.0530198800259 0.662854902576779 0.507986867184564 -73.6306555863346 73.2353764754957 -1.0053973793795 0.315602396692573 S1PR3 other 1 1 1 0.662854902576779 -1.0053973793795 5.3609619969411e-07 240.64362357446 43.6019241477693 5.51910559632429 7.92016279914856e-08 35.8378132023642 162.714527378398 0.220249622327957 0.825841365403886 SLC35F6 other 0.00488276418681396 1 0.00094154895356278 5.51910559632429 0.220249622327957 8.93185892880304e-10 1597.28313630477 323.374801459256 4.93941744717553 1.3699894230329e-06 -1311.36440072221 612.897007287693 -2.13961625710248 0.0332757889293726 CLIC1 other 9.67409640578657e-06 1 0.0150493338120164 4.93941744717553 -2.13961625710248 2.31432970632094e-05 310.732883579096 85.0223093418566 3.65472175461273 0.000308917094840461 -198.26359473848 161.144030744393 -1.23035022658063 0.219628964816262 DDAH2 other 0.18352634571125 1 1 3.65472175461273 -1.23035022658063 1.22209616802432e-08 146.799984061359 25.0784076635766 5.8536405512926 1.45008070928116e-08 -27.9274872625499 83.3715352262875 -0.33497628641177 0.73791410915877 ZNF337-AS1 other 0.000123822783744224 1 0.000178693445804717 5.8536405512926 -0.33497628641177 5.81199998961157e-06 16.3713102259239 4.04255373901608 4.04974461264887 6.6860449201813e-05 -8.69703348667765 7.78352620058377 -1.11736419491019 0.264821006025434 ATP6V1G2 other 0.0485301999132566 1 0.638517289877314 4.04974461264887 -1.11736419491019 1.6473256611117e-11 96.2918064368255 22.1491227241584 4.34743206925294 1.95563680430792e-05 -180.416404104937 49.2179240827762 -3.66566464285465 0.000297191105429936 ZNF134 other 1.93873757056236e-07 1 0.196033033263826 4.34743206925294 -3.66566464285465 1.38144462509217e-24 212.979867281018 20.5427588736656 10.3676370146195 1.87803761303071e-21 -58.2978954391253 40.4107988675974 -1.44263160028421 0.150270600310769 GTF2H4 essential 2.11001852036578e-20 1 2.89443156920293e-17 10.3676370146195 -1.44263160028421 1.13944056491846e-22 473.177006484711 44.345859916115 10.6701506607331 1.96661224211679e-22 -59.2728471022484 191.892255955031 -0.308886081969555 0.757644641619984 DDX47 other 1.71519988237176e-18 1 3.04411908957258e-18 10.6701506607331 -0.308886081969555 1.44096523749984e-13 50.7441379099452 8.06384759630997 6.29279476129556 1.24799182550193e-09 -47.9126818657828 19.9662005461321 -2.39968950302188 0.0170842697733656 ZNF845 other 1.82757621072105e-09 1 1.60766306961159e-05 6.29279476129556 -2.39968950302188 0.0390991454970789 3.48870732795358 4.69571222891802 0.742955947442598 0.458156680497742 -24.1262792771419 11.990051045004 -2.01219154001808 0.0451965029096513 ZNF321P other 1 1 1 0.742955947442598 -2.01219154001808 0.0200340917816121 -589.806380808774 797.572136873169 -0.739502238783157 0.460249321655684 -4235.41144780919 1553.64812546982 -2.72610726867669 0.00683108751855482 EMP2 other 1 1 1 -0.739502238783157 -2.72610726867669 0.000791439214108159 262.857906889078 80.7000389042883 3.25722156343483 0.00126839786519028 -232.846456507399 234.613764624769 -0.992467159289665 0.321855007958159 KCTD11 other 1 1 1 3.25722156343483 -0.992467159289665 4.7361943448652e-06 12.3091384330333 3.33738221284991 3.68826153193946 0.000273169867395145 -20.406341538733 10.7160652447071 -1.90427559675528 0.0579410965977088 C8orf44 other 0.0398598116063856 1 1 3.68826153193946 -1.90427559675528 0.632245486645495 -274.739184845961 316.735276397152 -0.867409490888119 0.386479473665177 -413.488785615621 597.594129392221 -0.691922435777871 0.489574086154814 UBD other 1 1 1 -0.867409490888119 -0.691922435777871 0.00776779422128507 9.64180976964212 3.47224468657858 2.7768232483474 0.00586935736931477 -3.57671888338972 9.65747893968049 -0.370357409602392 0.711403383152723 PPM1N other 1 1 1 2.7768232483474 -0.370357409602392 0.000142513416243687 -3.8864659253312 9.20078296651948 -0.422405999519124 0.673064878220858 -51.9772050184301 13.651168683638 -3.80752785515931 0.000173764112413784 SLC23A3 other 1 1 1 -0.422405999519124 -3.80752785515931 1.11348742457088e-06 634.837129197408 140.623370626601 4.51444967055368 9.46246632748776e-06 -16.0604640365421 275.584503701508 -0.0582778197642692 0.953570125354234 LTB4R other 0.00988220089306656 1 0.0973498535771941 4.51444967055368 -0.0582778197642692 1.83572871888564e-08 171.639295663303 33.4577398448015 5.13003258616621 5.51463448806622e-07 -11.072824750289 65.5682948646348 -0.168874679037311 0.86602072985175 LTB4R2 other 0.000184050161355474 1 0.00621775038529466 5.13003258616621 -0.168874679037311 1.0514690279788e-12 390.729945402513 69.1507621120591 5.65040692927336 4.0336453953696e-08 -202.887307523455 123.978319967986 -1.63647408333848 0.102896896761389 DNASE1 other 1.2948841079559e-08 1 0.000486296288865759 5.65040692927336 -1.63647408333848 8.14218660346791e-12 61.0179848667369 12.5607255362925 4.8578391980968 2.00605682863669e-06 -55.2322096320835 24.6156901063159 -2.24378066970838 0.0256512051671698 MDP1 other 9.68920205812682e-08 1 0.0217797589885086 4.8578391980968 -2.24378066970838 7.92283963770584e-10 419.817767425322 100.209098099107 4.1894176815175 3.78328915578219e-05 -444.260638438501 199.579963974118 -2.22597814726589 0.0268351978266995 IRF9 other 8.61529582204133e-06 1 0.369551684736804 4.1894176815175 -2.22597814726589 1.47735185386497e-15 206.294498428778 25.9642534544527 7.94532755546648 5.62772730632514e-14 37.661375316318 68.8069228939654 0.547348634880184 0.584601643901885 GALT other 1.98231071751602e-11 1 8.10336454837756e-10 7.94532755546648 0.547348634880184 0.00276272166621068 37.187295471251 11.0713242875747 3.35888413213458 0.000894053750840806 23.6138004951763 16.8565074725452 1.40087147551988 0.162388157453322 HBE1 other 1 1 1 3.35888413213458 1.40087147551988 0.127900678308325 -17.061935519692 14.7250254821192 -1.15870329327514 0.247597170020161 -54.0229925476259 26.5547615764392 -2.03439945759325 0.0428849078248522 CLDN9 other 1 1 1 -1.15870329327514 -2.03439945759325 0.57109031654658 -66.3513573171614 121.817219608686 -0.544679623540104 0.58642850905431 -236.013463093812 222.942924149959 -1.05862728765081 0.290726336327731 ITGA1 other 1 1 1 -0.544679623540104 -1.05862728765081 7.2534483249683e-23 224.596505264627 21.8725001973442 10.2684422557188 4.47101587975311e-21 -179.360582355375 80.1962855861544 -2.23651982188986 0.0261406554090334 NUDT19 other 1.09360240395547e-18 1 6.87776372782422e-17 10.2684422557188 -2.23651982188986 0.0283762320550519 23.7897340636106 8.91685825885141 2.66795023235852 0.00810911134138397 18.9045143496021 18.3979161608356 1.02753562872761 0.305119643523104 ZNF726 other 1 1 1 2.66795023235852 1.02753562872761 5.25730388757863e-05 410.599895988782 164.263024240436 2.49964894952729 0.0130189601847178 -1435.85463302131 492.789072721308 -2.91373066592599 0.00386700701041975 TAX1BP3 other 0.401765162166063 1 1 2.49964894952729 -2.91373066592599 2.97336957042491e-12 579.726960514413 104.901293219669 5.52640432468676 7.62963146083849e-08 -337.665824332444 213.062236567762 -1.5848224902354 0.114164324245334 AP1G2 other 3.59688516934302e-08 1 0.000907697254895955 5.52640432468676 -1.5848224902354 0.0859741010846461 250.02232765388 115.598836865403 2.16284466551331 0.0314309848975069 367.576530478394 261.334870412984 1.40653457342879 0.160715359579439 ZNF90 other 1 1 1 2.16284466551331 1.40653457342879 3.85370072677599e-21 353.688485512637 41.7347598588347 8.47467402972885 1.65774560619853e-15 -181.273707671845 82.3818189778126 -2.20040914270983 0.028640904015894 NAXD other 5.71426743766344e-17 1 2.44020153232423e-11 8.47467402972885 -2.20040914270983 0.090422478446061 1.48924823376089 1.68630921958344 0.883140657991993 0.377943020715383 8.54151519308596 3.8836853504085 2.1993324439086 0.0286990258346694 TM6SF2 other 1 1 1 0.883140657991993 2.1993324439086 2.48230845628591e-05 11.7663682864451 7.3451824500876 1.60191640798585 0.11033476374561 -54.6558844842285 16.9164233223818 -3.23093619984753 0.0013856014446466 MEF2B other 0.196201660384838 1 1 1.60191640798585 -3.23093619984753 9.31419830631934e-07 66.5003835298645 24.5832914702128 2.70510495351861 0.00725771168088554 -116.43580975137 42.9105450111027 -2.71345446023216 0.00708208223449415 GANC other 0.00830640204957559 1 1 2.70510495351861 -2.71345446023216 0.0014220442050097 121.611879228544 45.8515496752162 2.652295943975 0.00846425211638379 -202.767630049692 127.406494757903 -1.59150151987927 0.112658242264592 TTLL3 other 1 1 1 2.652295943975 -1.59150151987927 4.47297316975476e-09 551.721193924047 123.711595183274 4.45973712574552 1.2082000291229e-05 -751.231273081134 312.844701397218 -2.40129134272055 0.0170188486053451 REPIN1 other 4.65010290727705e-05 1 0.123260566971118 4.45973712574552 -2.40129134272055 0.0364171409626452 23.6991765311374 14.6873851688382 1.61357357070061 0.107796759393631 -49.6018309253332 30.3271382820845 -1.63555922962356 0.103105755829907 ZNF891 other 1 1 1 1.61357357070061 -1.63555922962356 7.04693719269289e-29 270.854520516953 30.3544512635073 8.92305771452306 6.97445855353468e-17 -285.57547844564 67.5174677674729 -4.22965327178959 3.20454425402649e-05 SMIM7 other 1.0988289164566e-24 0.486449817761221 1.04289078751004e-12 8.92305771452306 -4.22965327178959 0.935631989707041 -18.1105651628273 60.9445045348443 -0.297164860081401 0.7665691415986 7.4102248548039 141.391798680001 0.0524091561461409 0.958241432536467 UCA1 other 1 1 1 -0.297164860081401 0.0524091561461409 6.64425302520763e-12 233.326026492647 49.9730868412781 4.66903369875318 4.77383127149168e-06 -150.921225763384 85.0210559778579 -1.7751041083598 0.077007243561037 FBXO16 other 7.92991598558531e-08 1 0.0503066339389793 4.66903369875318 -1.7751041083598 0.228476651364717 -25.508768306104 91.4623836656518 -0.278899010541355 0.78053425514065 -202.347723355625 141.01989645133 -1.43488776014994 0.152467882532493 TSPAN4 other 1 1 1 -0.278899010541355 -1.43488776014994 5.32847830709737e-30 1843.69983050581 145.175517952732 12.6997985370103 3.32541935075934e-29 -533.106113811382 618.316211281253 -0.862190096401805 0.389359531915263 CPNE1 other 8.34706126806803e-26 1 5.23886564518627e-25 12.6997985370103 -0.862190096401805 2.62090486113348e-12 191.234651443944 27.1594309389778 7.04118771389626 1.60138109375989e-11 -20.77812632888 60.3416422577822 -0.344341412520974 0.730859583153621 ARL16 other 3.17915759655492e-08 1 2.19100961248229e-07 7.04118771389626 -0.344341412520974 4.37227880616039e-14 32.227698324783 5.76089498829763 5.59421728572533 5.50010651188654e-08 -42.6112407250403 14.5476335752724 -2.92908399875218 0.00369433487444014 PAXIP1-AS2 other 5.63849074842444e-10 1 0.000659517771840315 5.59421728572533 -2.92908399875218 5.67004455027997e-13 240.446316520176 33.2974443767343 7.22116429716696 5.33565284716988e-12 -11.9419604292633 59.9377266983907 -0.199239462139693 0.842226508665685 LYRM4 essential 7.05353542054828e-09 1 7.38934562804557e-08 7.22116429716696 -0.199239462139693 6.64515008465594e-11 75.2510595009651 25.8702501221495 2.90878747386121 0.00393016070383988 -170.798456920221 40.914084988484 -4.17456377108997 4.03133146972717e-05 MYCBP other 7.6193290870665e-07 0.61054515109018 1 2.90878747386121 -4.17456377108997 0.0989306160637672 12.9177059573366 16.6311784692504 0.776716212938264 0.438001142099391 -72.5887904156278 45.9571556266825 -1.57948831745112 0.115386274566239 TMEM213 other 1 1 1 0.776716212938264 -1.57948831745112 0.915961008079871 0.513201339173136 5.98587694699273 0.0857353640440212 0.931740096355296 -5.00721429242569 13.3213921987185 -0.375877702400157 0.707301884894765 PRCD other 1 1 1 0.0857353640440212 -0.375877702400157 2.24313890638534e-38 643.637438411669 41.3306454002345 15.5728862247096 2.20947787243248e-39 711.053857522177 449.389903726642 1.58226486982828 0.114768496133815 ALG3 other 3.55515085273013e-34 1 3.509755600359e-35 15.5728862247096 1.58226486982828 1.4705828721298e-07 78.2479542455703 14.487422050288 5.40109579012472 1.4536088879358e-07 -21.8243815968831 31.6050333938347 -0.690534995642195 0.490450992834553 AMZ2P1 other 0.00139293609648135 1 0.0017022120343133 5.40109579012472 -0.690534995642195 7.64286377675653e-06 2.49488826479065 0.556807793034392 4.48069925744835 1.09832373282473e-05 -1.87977087562217 1.94392006137953 -0.967000090676651 0.334406161233025 GCC2-AS1 other 0.0632064834337765 1 0.112402450817282 4.48069925744835 -0.967000090676651 0.00220648900083264 19.4101820361819 7.53182631951752 2.57708837309266 0.0104948782426704 -15.0373590742758 16.3807425809932 -0.917990072789728 0.359443358835682 ZNF788 other 1 1 1 2.57708837309266 -0.917990072789728 6.14413739126976e-06 114.872766214249 31.6380514788468 3.6308420033722 0.000337487324019995 -48.6406737743912 45.1543706645675 -1.0772085416874 0.282341554186108 SH3D21 other 0.0511683761944946 1 1 3.6308420033722 -1.0772085416874 3.86013977480914e-06 5.41237670585055 1.19706568495087 4.52136985788935 9.16640344051506e-06 -2.18731135040506 2.58170278229921 -0.847235927156993 0.397605753807369 TTC41P other 0.0327378454301563 1 0.0944139554373051 4.52136985788935 -0.847235927156993 0.731585330907318 -1.42965743448863 4.40206936815604 -0.324769401597933 0.745608968197427 4.04143823045318 8.44779685032717 0.478401446206257 0.632754534660152 C19orf38 other 1 1 1 -0.324769401597933 0.478401446206257 7.48440829202336e-05 8.02962976519462 1.89717730872165 4.23240870965567 3.16793776169938e-05 -0.532971625045346 4.04483690329358 -0.131765912393492 0.895267221630306 C17orf67 other 0.562602971311396 1 0.311788434506453 4.23240870965567 -0.131765912393492 0.974551712923584 -0.26141183519655 1.15419820088184 -0.226487820719893 0.821006367554587 -0.196042320367079 2.33740080650717 -0.0838719315152586 0.933225109388471 CTAGE11P other 1 1 1 -0.226487820719893 -0.0838719315152586 1.00877839905795e-08 263.139749789914 50.4218050234444 5.21876893672416 3.58675928823249e-07 -440.154012871632 214.5006089866 -2.05199423419412 0.0411309546172409 FIS1 other 0.000102754167728042 1 0.00410002454237856 5.21876893672416 -2.05199423419412 0.000102404617190278 27.3082000425719 6.26425748238729 4.35936743011478 1.85171034517307e-05 6.67284783567225 21.1607597142337 0.315340655334968 0.752744818074064 ANKRD36BP1 other 0.758203785676821 1 0.18605985548299 4.35936743011478 0.315340655334968 0.0143205845612874 -41.5905801563484 87.0685052691373 -0.477676514921071 0.633269816780678 -440.563521333992 161.873970340334 -2.72164524294871 0.00692143445342776 SNURF other 1 1 1 -0.477676514921071 -2.72164524294871 0.212869935840078 4.53694025755815 14.4927413817554 0.31304914219125 0.754483226501772 -42.3451806552608 31.0398587306221 -1.3642195031476 0.173626196024838 ANG other 1 1 1 0.31304914219125 -1.3642195031476 0.00276073425112681 4.97262876412683 8.92356882999394 0.5572466418831 0.577836488453902 -29.7363662135117 12.538698143913 -2.37156727693835 0.0184389528505604 SCART1 other 1 1 1 0.5572466418831 -2.37156727693835 0.00739886121288668 158.311898108558 66.5151696254669 2.38008711396182 0.0180004677357862 -71.4884652610384 119.564339555336 -0.597907917418409 0.550400698632336 COLCA2 other 1 1 1 2.38008711396182 -0.597907917418409 7.79335127401775e-08 57.2217234782327 11.4277271868699 5.00727069718454 9.95948899930992e-07 -45.8902658647347 35.617653144617 -1.2884135200713 0.19870095677641 APTR other 0.000751434929840792 1 0.0110500530447344 5.00727069718454 -1.2884135200713 1.66725730311663e-13 27.1976939787123 3.73603749151387 7.2798236207452 3.59979633309604e-12 -30.1670237433289 16.4730307857823 -1.83129772144697 0.0681498372631521 SPDYE3 other 2.11041429428503e-09 1 5.00911659750313e-08 7.2798236207452 -1.83129772144697 1.07889977504414e-07 8.38934005381181 1.47846250843543 5.67436780164939 3.55994482174254e-08 -0.313284042406484 6.51887420091521 -0.0480579978614254 0.961705287989173 MBLAC1 other 0.0010315360749197 1 0.000430290530604021 5.67436780164939 -0.0480579978614254 0.798672051676809 16.0589938044289 23.9466961076076 0.670614172922468 0.503039571923723 13.1784617346399 108.33206475432 0.121648763591154 0.903267679498912 AZGP1P1 other 1 1 1 0.670614172922468 0.121648763591154 0.805058520205375 8.93467497473897 13.5646735846191 0.658672316661563 0.510673806212423 5.40359895389614 52.8871793971929 0.102172190226181 0.918696691259694 FOXI3 other 1 1 1 0.658672316661563 0.102172190226181 0.333635462186369 8.92257115260525 18.9817364654924 0.470060848691367 0.63868820010553 -41.3949057371238 35.3423568211238 -1.17125481887452 0.242521375149698 SOGA3 other 1 1 1 0.470060848691367 -1.17125481887452 6.56450572980991e-16 5.07042128543138 1.163757383258 4.35694016499942 1.87330773011861e-05 -8.52317614955375 2.01000704174318 -4.24037128853141 3.06438535995412e-05 VAC14-AS1 other 8.88111980185983e-12 0.465572067737829 0.188155028413113 4.35694016499942 -4.24037128853141 1.27678485557975e-05 85.9272969105635 88.7482505100347 0.968213980745996 0.333797630905984 -531.483770131278 143.824787032826 -3.69535586386771 0.000265469224949447 NEURL1B other 0.103585555333185 1 1 0.968213980745996 -3.69535586386771 9.45905514066807e-21 76.5424104915813 14.2127621942433 5.38547042759809 1.56395955436283e-07 -80.0494506556456 22.7466775018432 -3.5191711250647 0.000507272928744938 HAUS3 essential 1.39625112931401e-16 1 0.00182858151096102 5.38547042759809 -3.5191711250647 0.0630406511680975 8.65295734654419 6.06297659722059 1.42717973717908 0.154692153912083 -8.84900832009946 10.792832634514 -0.819896742566132 0.413003557209183 VSTM5 other 1 1 1 1.42717973717908 -0.819896742566132 5.99537702494009e-09 128.416273317161 29.9666516186086 4.28530604458381 2.54098156474529e-05 -64.8795403060195 42.472458900981 -1.52756732209166 0.127790607362078 BBIP1 other 6.19262492906062e-05 1 0.25239569882615 4.28530604458381 -1.52756732209166 0.060106448860388 29.9164709858751 24.1001169392063 1.24134132051478 0.215549130207885 -35.990082541716 36.3175220244949 -0.990983980609743 0.32257413862181 AS3MT other 1 1 1 1.24134132051478 -0.990983980609743 0.0535610197880596 -11.9436223071668 6.42700504771069 -1.85834960739935 0.0641956537427663 2.54680870325769 11.7157951371142 0.217382488636192 0.828072654679868 PLIN5 other 1 1 1 -1.85834960739935 0.217382488636192 0.462699711811533 -0.914838227005383 7.98663416672196 -0.114546153975257 0.908889060848621 28.9648272323561 25.3400854674252 1.14304378608314 0.254021803744926 SEC14L6 other 1 1 1 -0.114546153975257 1.14304378608314 0.278320843226307 27.9687244708448 64.9349787803534 0.43071892832137 0.667015122483487 -148.868183851605 124.508350916154 -1.19564818549284 0.232879043825976 KRT42P other 1 1 1 0.43071892832137 -1.19564818549284 3.35824230131471e-19 526.554444903739 71.9601628369654 7.31730479955573 2.8746636554739e-12 -642.434515271879 190.398856188725 -3.37415112743688 0.000848620675656713 PPME1 other 4.85333177386002e-15 1 4.00843100119281e-08 7.31730479955573 -3.37415112743688 4.93487490547303e-08 369.156986893874 83.1994299683396 4.43701341504805 1.3405657927109e-05 -428.241746788607 203.416032568001 -2.10525070901404 0.0362143318065202 STARD10 other 0.000481643790774168 1 0.136228295855281 4.43701341504805 -2.10525070901404 0.410668864176445 -286.257145962397 566.235825449801 -0.505544038537304 0.613589223936745 -1664.33047439947 1248.38220522075 -1.33318984157194 0.183593275872219 MEG3 other 1 1 1 -0.505544038537304 -1.33318984157194 0.000163684776395776 2.96530678663218 6.04074816783153 0.49088402698579 0.623914727225942 -25.7965215714268 8.65499986420436 -2.98053402382095 0.0031447892369933 NUTM2D other 1 1 1 0.49088402698579 -2.98053402382095 0.985822582386832 1.09876799232463 8.10175586894884 0.135620970330125 0.89222198220201 2.23784524503567 15.778829366312 0.141825809322299 0.887323363673209 CPEB1 other 1 1 1 0.135620970330125 0.141825809322299 0.0804048922449839 14.241512840304 13.2017236313114 1.07876162522646 0.281667584934429 128.672611026907 62.7593478733115 2.05025411173249 0.0413160972258332 EML6 other 1 1 1 1.07876162522646 2.05025411173249 2.43318185076376e-06 151.619291368343 29.4557660066093 5.1473552354511 5.28115575037719e-07 113.477741421078 59.7736482869486 1.89845767613712 0.0587648105922454 SLC6A10P other 0.0209689407453064 1 0.00596136861102577 5.1473552354511 1.89845767613712 1.24916122774227e-08 119.457892637471 100.132650198851 1.19299641425891 0.233918065297311 -650.631088498448 156.937042779221 -4.14580953595357 4.53751185137871e-05 ZSWIM8 other 0.000126490065921183 0.686026416809948 1 1.19299641425891 -4.14580953595357 0.447772863056349 6.58867111109418 7.01600075515558 0.939092132544686 0.348516609272306 -0.822325233636763 10.9985584605454 -0.0747666375176939 0.940455344126077 C10orf105 other 1 1 1 0.939092132544686 -0.0747666375176939 0.775912339942522 2.18280058260638 3.12056777335457 0.699488279422914 0.484844684824574 2.08258602057916 11.4903183666378 0.181247025028129 0.856308668711948 ARHGEF33 other 1 1 1 0.699488279422914 0.181247025028129 3.0024878609545e-08 311.171685878962 53.1709812753984 5.85228405447799 1.39106928876096e-08 46.9633141210378 126.124735687116 0.372356095457295 0.709917691586886 IFRD2 other 0.000297426447506153 1 0.000171546664690001 5.85228405447799 0.372356095457295 0.619052654479763 -2.54496909239605 27.461083959642 -0.0926754783655389 0.926229600416757 -102.5171711351 105.033003648406 -0.97604721919857 0.329908322901025 CAPN14 other 1 1 1 -0.0926754783655389 -0.97604721919857 6.97006721365852e-05 20.0221273888895 5.34668958068112 3.74477086929345 0.000221346135861864 -2.70399001538309 10.6023177756385 -0.255037631639017 0.798891108920107 CDIPT-AS1 other 0.525891571270535 1 1 3.74477086929345 -0.255037631639017 1.72297713702547e-25 876.595586407875 80.8960652683464 10.83607198323 5.72982755173925e-23 -121.934419878461 172.731554639352 -0.705918615351143 0.48084514436125 TOMM6 other 2.64683747789853e-21 1 8.89498429132001e-19 10.83607198323 -0.705918615351143 2.16893584938458e-07 759.005954033998 203.183696238079 3.73556524508069 0.000228518329197621 -1163.09123313507 413.941206314099 -2.80979814377918 0.0053198213358712 HNRNPUL2 other 0.00203250978445829 1 1 3.73556524508069 -2.80979814377918 3.92186853430676e-05 25.7339311855588 7.78062679046713 3.30743677579912 0.00106978189156614 -31.0900632958052 15.9173669689882 -1.95321646830019 0.0518306122155932 METTL12 other 0.303591843240686 1 1 3.30743677579912 -1.95321646830019 0.107505851882199 30.9075006870931 14.5989491701447 2.1171044797046 0.0351587346358536 29.698579375835 40.1382392625972 0.739907378137277 0.459994331937706 SEPT7P2 other 1 1 1 2.1171044797046 0.739907378137277 3.83443999895736e-05 126.662853154559 30.4171873278166 4.16418690490575 4.20301578761966e-05 -48.2853753425787 87.9823860013533 -0.548807295835737 0.583589567496407 POLR2J4 other 0.297130755519206 1 0.409121556766898 4.16418690490575 -0.548807295835737 0.171424909949257 -0.846317854106555 1.67297446717013 -0.505876133027971 0.613351835216099 -7.40743257264883 3.94707074338115 -1.87669110949439 0.0616270170638985 MS4A4E other 1 1 1 -0.505876133027971 -1.87669110949439 0.607037179253444 -4.77343069854107 7.07051021799689 -0.675118280204312 0.500178348345023 -25.7348889732466 30.6091683147561 -0.840757537369621 0.401227723246899 FER1L6 other 1 1 1 -0.675118280204312 -0.840757537369621 0.0319072646127063 -12.2602157468626 95.0434839200088 -0.128995857908377 0.897456609801119 -537.052755329575 235.256976075625 -2.28283455941785 0.0232148001554691 KRT16P3 other 1 1 1 -0.128995857908377 -2.28283455941785 0.359736061277992 5.77686577082855 4.41983904138658 1.30703080287201 0.192310197640607 8.50384417461002 11.7991175548293 0.720718658416065 0.471703862020341 LINC01347 other 1 1 1 1.30703080287201 0.720718658416065 0.911841362500427 -1.69608849733382 7.07304794378358 -0.239795984816487 0.810669694679686 -8.39442722407413 20.1366509796635 -0.416873055631339 0.677101277888995 APOC1P1 other 1 1 1 -0.239795984816487 -0.416873055631339 0.0118430384996629 24.9371167354221 10.5523124399166 2.36318976313587 0.0188194782188166 -12.1110894045672 27.3780645713278 -0.442364703064174 0.658575574166091 EVPLL other 1 1 1 2.36318976313587 -0.442364703064174 0.00281890432711835 8.4777390975964 6.29945418265839 1.34578946870263 0.179507805605993 -24.4867612720667 11.6854297625447 -2.09549513964426 0.0370653332016363 LINC01588 other 1 1 1 1.34578946870263 -2.09549513964426 0.0535620146066409 14.1273789456075 6.01520901738903 2.34860981634511 0.019557056823525 2.99915929981683 11.4166904549615 0.262699537282581 0.792980309296778 HLA-F-AS1 other 1 1 1 2.34860981634511 0.262699537282581 3.143505151485e-10 48.8220238682318 11.6400744688898 4.19430511365863 3.70355088993704e-05 -102.649651660106 30.3220779129143 -3.38531059628955 0.000815405160966802 ZSWIM7 other 3.48991941917865e-06 1 0.362281348053641 4.19430511365863 -3.38531059628955 0.0424844981649587 59.0558540407419 63.3509530303775 0.932201509461491 0.352059098125501 -157.69876467835 98.4533044217193 -1.60176202926471 0.110368924340702 ARHGEF28 other 1 1 1 0.932201509461491 -1.60176202926471 0.0344927844524663 6.2388379530016 2.76306070410493 2.25794458432741 0.0247508016688866 -6.22857888170418 9.62268636016539 -0.647280670758257 0.518002291990119 LRRC69 other 1 1 1 2.25794458432741 -0.647280670758257 0.44078169642853 6.61306228336547 5.72872422587427 1.15436910953001 0.249362082204206 -4.05170529465813 15.4119735849778 -0.262893345379684 0.792831805034052 ISPD other 1 1 1 1.15436910953001 -0.262893345379684 0.0218962999330576 37.0152126767029 13.5786528243251 2.72598564493769 0.00682568700485294 0.815710531731312 35.9385567912243 0.0226973647403253 0.981908258701715 COL28A1 other 1 1 1 2.72598564493769 0.0226973647403253 7.36130226105355e-24 1729.41984045537 152.253521209539 11.3588167072685 1.02885035559629e-24 613.487837593109 731.41577170931 0.83876758107006 0.402338979859554 PHB2 essential 1.11906516972536e-19 1 1.60644694522805e-20 11.3588167072685 0.83876758107006 2.91029361208326e-12 168.55351981987 21.9977018415314 7.66232404794406 3.28846876118997e-13 155.319284416088 104.02560502294 1.49308705661299 0.136582004836878 CD27-AS1 other 3.52174629998196e-08 1 4.68475259719123e-09 7.66232404794406 1.49308705661299 7.88904485552616e-13 204.696431046706 26.8363195589466 7.62758956559171 4.0677111838787e-13 15.9865434044767 80.2917313413493 0.19910572530205 0.842329343973241 NEURL4 other 9.76111519974252e-09 1 5.7846920745939e-09 7.62758956559171 0.19910572530205 0.0551572037307076 1.83179299643636 1.89147009700667 0.968449355522594 0.333677183945778 -9.81585750868762 5.01202236045138 -1.95846243347638 0.0511938785357434 GRID2IP other 1 1 1 0.968449355522594 -1.95846243347638 0.000111302700610243 35.9719169444192 9.38950734398468 3.83107607530276 0.000158356047860887 -26.1846993807843 28.1289611823959 -0.930880426440051 0.352737859406614 ALOX12-AS1 other 0.820634811599325 1 1 3.83107607530276 -0.930880426440051 4.46477006908191e-13 147.339230626682 22.1707175529578 6.64566811041376 1.74123680273895e-10 -121.439545346246 67.1966374060903 -1.80722652254679 0.0718739749624292 UBXN2B other 5.56890770716587e-09 1 2.31096948459513e-06 6.64566811041376 -1.80722652254679 0.399398514350289 -158.498885769254 180.907459689856 -0.87613239410349 0.381733987910036 38.8810553580289 282.403783927908 0.137678946143138 0.890596397727645 MUC5AC other 1 1 1 -0.87613239410349 0.137678946143138 1.96555805730745e-35 57.9208038434755 4.99242330124682 11.6017413485371 1.93952619873624e-25 -29.2001668993921 13.9829490192256 -2.08826956740269 0.0377281820559728 MSMP other 3.10695762118588e-31 1 3.03303106958373e-21 11.6017413485371 -2.08826956740269 0.54802233247124 1.647208571979 4.96447704517281 0.331799010649199 0.740301331183655 -10.6916692913867 14.0756586619821 -0.759585718021467 0.448172378883808 FAM166B other 1 1 1 0.331799010649199 -0.759585718021467 6.43963218067848e-30 446.059568077804 42.3437425247283 10.5342499618996 7.04116908036402e-22 -435.296231901632 121.737989221949 -3.57568113851471 0.000415577767648688 PEX26 other 1.00844639949425e-25 1 1.08743815277142e-17 10.5342499618996 -3.57568113851471 0.0674598666060768 5.46140042439859 5.21023119263214 1.04820692642615 0.295480667645009 -60.1908651954487 30.465553408582 -1.97570234120524 0.0492065888906903 C5orf49 other 1 1 1 1.04820692642615 -1.97570234120524 0.0264070531805713 24.4065582098791 9.50456128583228 2.56787846128786 0.0107688410300377 62.0884140822534 54.9348932351965 1.13021816236959 0.259383621465717 UBE2QL1 other 1 1 1 2.56787846128786 1.13021816236959 2.53941935873242e-19 147.416378608689 15.8162928472561 9.32053927126567 4.13971409452416e-18 -102.417095870309 56.8592281101095 -1.80123964525116 0.07277256542052 FASTKD5 essential 3.67606346370105e-15 1 6.26048962514889e-14 9.32053927126567 -1.80123964525116 4.44351973705555e-18 103.207174553401 25.8652463460925 3.99018718679215 8.48771913283856e-05 -273.2620754208 51.4006333057848 -5.31631728728227 2.20428651680258e-07 DHRS4-AS1 other 6.30446580293441e-14 0.00347505769373926 0.80174994928793 3.99018718679215 -5.31631728728227 1.13965549052007e-15 225.512046480785 34.217973637313 6.59045590691773 2.25320825301686e-10 -104.009851905649 69.6710814913802 -1.49286977723343 0.136626035180026 HOMEZ other 1.5332924969457e-11 1 2.97738938553648e-06 6.59045590691773 -1.49286977723343 3.55039228310742e-07 5.24408084550493 1.24076721808403 4.22648242883364 3.24002506470616e-05 -2.18621785763153 2.52632125090834 -0.865376031193765 0.387592247010904 RNF212B other 0.00328233766573281 1 0.318364862858027 4.22648242883364 -0.865376031193765 2.727456181329e-19 231.675819889538 26.1103825785923 8.87293854052857 9.740397398626e-17 -250.775969669548 93.1294176100617 -2.69276858059568 0.00752603392357001 VPS16 other 3.94662909438307e-15 1 1.45463094751081e-12 8.87293854052857 -2.69276858059568 2.32130618031802e-07 3.31603998708016 2.02064844310629 1.64107714946322 0.101945727369746 -11.2431845682395 3.38234264755932 -3.32408207558526 0.00100983743587917 FAM66B other 0.00217065340921538 1 1 1.64107714946322 -3.32408207558526 1.94275104937531e-44 445.235709849578 27.1645351500404 16.3903305317159 3.98025563167724e-42 128.497949662628 74.5396658597635 1.72388684843824 0.0858989450100828 MYL5 other 3.08916844361168e-40 1 6.32701435211414e-38 16.3903305317159 1.72388684843824 1.26842329538395e-12 78.4538775385926 17.3945708880682 4.51025081581105 9.69307849142385e-06 -77.3951800992602 26.8266616614427 -2.88500973680591 0.00423218682817834 ZNF407 other 1.55686275275427e-08 1 0.0996448468918372 4.51025081581105 -2.88500973680591 4.1076468803281e-17 141.107387928875 25.5736440824594 5.51768795537663 8.04777149132017e-08 -140.714266633275 38.9560847942868 -3.61212548376812 0.000362052406147392 MCM3AP-AS1 other 5.72277363367311e-13 1 0.000955833820024097 5.51768795537663 -3.61212548376812 6.45645071328756e-05 201.985214881154 56.3665446051136 3.58342375421802 0.000401740678359936 -274.079936794734 169.133610233832 -1.62049362285716 0.106284982196556 NPEPL1 other 0.48946352857433 1 1 3.58342375421802 -1.62049362285716 3.63403031912832e-06 -8.63925260591325 21.3108914537707 -0.405391422721766 0.685509667017078 -140.79855543925 30.9020853982292 -4.55628005763384 7.88185643579059e-06 AATBC other 0.0308638195003568 0.121546108096327 1 -0.405391422721766 -4.55628005763384 0.139365362344614 17.7802030862716 9.07932764397548 1.95831715557369 0.0512223344374229 13.5543418762416 13.2697865565796 1.02144385054339 0.307958532850278 HMX1 other 1 1 1 1.95831715557369 1.02144385054339 0.532518111174095 1.6010766663564 8.84277007986302 0.181060533282711 0.856456914395666 -19.0408345410789 19.6483086012364 -0.969082628307289 0.333377713144159 GCGR other 1 1 1 0.181060533282711 -0.969082628307289 2.30014010060852e-11 67.6833898555001 15.2775159720071 4.4302614364479 1.36367345237582e-05 -59.2874668239458 23.729790611398 -2.49844036952727 0.013062416429553 RSC1A1 other 2.68909379162143e-07 1 0.138494675823289 4.4302614364479 -2.49844036952727 2.35568107851135e-14 106.083666138206 14.9320731268194 7.10441646228413 1.05208064851802e-11 -61.6552585947682 29.5939609323767 -2.08337298057711 0.0381475620828815 TMEM242 other 3.05979415287839e-10 1 1.44661089171228e-07 7.10441646228413 -2.08337298057711 5.59877823005254e-24 69.1526382298092 47.2333839342818 1.46406275540251 0.144331542276918 -558.695773353483 70.4221595356811 -7.93352230373461 5.57691275457347e-14 TMEM167B other 8.51910095484795e-20 8.90800274288021e-10 1 1.46406275540251 -7.93352230373461 0.0244245954503619 20.1892923544805 7.57726079109569 2.66445789726621 0.00821908971873242 -15.0877729036677 25.5495363185028 -0.590530204367791 0.555375158048286 FAM72D other 1 1 1 2.66445789726621 -0.590530204367791 0.00637454633907142 7.44418755687586 51.2947572563567 0.145125700072464 0.884720306160922 -208.530850166059 80.532019257049 -2.58941539141658 0.0101373684752393 TNFRSF25 other 1 1 1 0.145125700072464 -2.58941539141658 4.5440915088465e-07 42.8933924919388 13.9945854948568 3.0649991389672 0.00239888157205008 -48.4698675639951 22.1449743358809 -2.18875248301646 0.0294778781707045 SLC35E2 other 0.00416420545870693 1 1 3.0649991389672 -2.18875248301646 0.019956352569644 19.4505345108472 13.4701695341903 1.44397102512165 0.149910772795354 -84.0666915391913 37.1050552241637 -2.26563984425618 0.0242685840642256 LINC01139 other 1 1 1 1.44397102512165 -2.26563984425618 0.420736684776624 3.19606475599448 3.30675590552283 0.966525757361323 0.33464609024108 -9.29484627694003 11.0743947479424 -0.839309640706727 0.402038081862865 FMO9P other 1 1 1 0.966525757361323 -0.839309640706727 3.53416035328482e-07 198.71490314503 35.64167467034 5.57535258887245 5.96841372018253e-08 -27.3377446216132 120.932978239323 -0.226056986436839 0.82132749786082 TSTD1 other 0.00326768466264714 1 0.00071412070161984 5.57535258887245 -0.226056986436839 0.432905930063384 14.9077198394814 12.7829299791218 1.16622087923738 0.244546686181495 37.0094198270286 54.9645921620702 0.673332019237068 0.501307794676409 RPTN other 1 1 1 1.16622087923738 0.673332019237068 3.40556515039943e-14 76.9461381889468 11.5382071919679 6.66881231275785 1.43463655562325e-10 -14.7582654754016 20.4391471126691 -0.722058772513741 0.470878632892269 CYB5RL other 4.4037362959815e-10 1 1.90864047360117e-06 6.66881231275785 -0.722058772513741 0.000994544106253079 20.0366080383342 11.6270164488476 1.72328026940395 0.0859742840345888 -34.1093207904612 18.1946079168719 -1.87469391735732 0.0619064254397312 C1orf167 other 1 1 1 1.72328026940395 -1.87469391735732 0.174367081980657 6.09700286872183 3.40501987665824 1.79059244573502 0.0744831073685926 2.59819407130823 5.42642297589244 0.478804192531809 0.632466888954144 TTC34 other 1 1 1 1.79059244573502 0.478804192531809 0.0356884866937236 3.47068328772635 9.24295872037579 0.375494838040912 0.707589506741171 -28.4060349944508 14.6260197363869 -1.94215757303963 0.0531656491375413 MMP23A other 1 1 1 0.375494838040912 -1.94215757303963 0.0206595650680869 33.0009235742325 21.5744823796925 1.52962759399944 0.12730623713117 -38.1223612164792 33.8439579203608 -1.12641557190758 0.2610125187693 ATAD3C other 1 1 1 1.52962759399944 -1.12641557190758 0.691758595210356 -1.54432200895925 4.33765808805859 -0.356026680205779 0.722097582117152 -8.54253588594973 10.0463608705179 -0.850311470596155 0.395902565690217 KRT19P2 other 1 1 1 -0.356026680205779 -0.850311470596155 0.63407293517258 -318.586436867028 387.456819555892 -0.822250172889449 0.411652100161488 56.2207730066928 887.556942128957 0.0633432857522782 0.949539501714774 IFI30 other 1 1 1 -0.822250172889449 0.0633432857522782 0.0155704866256887 17.289089137847 5.95190564708158 2.90479892710067 0.00397561900692651 14.5162434613186 10.3037237071268 1.40883469645815 0.16002199090349 CCDC7 other 1 1 1 2.90479892710067 1.40883469645815 9.08723662889332e-09 131.525988167016 27.8374949765605 4.72477815542536 3.69760942617741e-06 -58.5782534542224 44.8704230605379 -1.30549813125654 0.19282644193621 FNIP1 other 9.28624711106609e-05 1 0.0392981929814136 4.72477815542536 -1.30549813125654 0.337340346725144 7.69350695628597 5.45650160403831 1.40997062121123 0.159699248957199 0.447672639191278 15.8206520303021 0.0282967249601235 0.977446396402073 SP9 other 1 1 1 1.40997062121123 0.0282967249601235 0.00109390660397621 65.5349782337363 32.3182948477317 2.02779814165647 0.0435519917199735 -84.0649487046787 56.4659013989399 -1.48877369566365 0.137701222463913 CKLF other 1 1 1 2.02779814165647 -1.48877369566365 2.91576517318317e-08 116.315712021734 23.5608792351622 4.93681542444922 1.3868602730904e-06 -25.5834593615579 45.5450748748062 -0.561717363115144 0.574771143360839 PAM16 essential 0.000289098116921111 1 0.0152263389382595 4.93681542444922 -0.561717363115144 0.00047527668965676 154.634881396519 63.2200524655243 2.44597837815534 0.0150845999359822 -83.2238794402793 94.8943493199321 -0.877016176797775 0.381257511009683 TENM3 other 1 1 1 2.44597837815534 -0.877016176797775 9.88513614282043e-09 11.5325269213748 2.31626676392566 4.97892863679883 1.13694360087576e-06 -8.32517873826031 4.33968923244231 -1.91838131542314 0.056109403617157 RAET1K other 0.000100808618384483 1 0.0125518573536684 4.97892863679883 -1.91838131542314 1.63297337674832e-12 70.497923187126 21.1471031765559 3.33369174011887 0.000976470913871972 -112.464883138478 31.4148820870944 -3.57998743483045 0.000407064026971732 LINC00339 other 1.99728973710087e-08 1 1 3.33369174011887 -3.57998743483045 1.23104635001611e-07 350.702311959106 60.4180731490899 5.80459279285024 1.79325059135646e-08 139.244077935396 223.349872801488 0.623434776070615 0.533521274897583 CEBPZOS other 0.00117220233448534 1 0.000219870455006215 5.80459279285024 0.623434776070615 7.17328758701962e-08 38.362602470237 12.6834004377395 3.02463070992295 0.00273009277850087 -94.6447375191814 28.0371524880015 -3.37569007978555 0.000844915659790054 ZNF579 other 0.000693369978161316 1 1 3.02463070992295 -3.37569007978555 9.08616599306565e-06 247.337649761282 74.6633688188087 3.31270412351089 0.00104869354477419 -584.988614421732 223.675526980301 -2.61534474655894 0.00940946956366822 RNASEK other 0.0747428014589581 1 1 3.31270412351089 -2.61534474655894 0.21676352453755 -4.98472919891156 18.6767608982879 -0.266894737586351 0.789756228444273 -68.3333147081337 40.5916000684841 -1.68343486319449 0.0934597210237217 FAM19A5 other 1 1 1 -0.266894737586351 -1.68343486319449 0.377554140761491 74.1377206855369 55.5542926947972 1.33450930772952 0.183165496195763 -4.07016751121581 152.605022794215 -0.0266712552227351 0.978741715265909 RPL23P8 other 1 1 1 1.33450930772952 -0.0266712552227351 3.23799008856276e-07 37.7556763460296 10.5765890075564 3.56974033112711 0.000422318427709266 -97.7650130871894 27.9018853055274 -3.50388556245058 0.000535951152328251 UMAD1 other 0.00300096921407997 1 1 3.56974033112711 -3.50388556245058 0.00871002962410039 34.2133249792893 14.2661606476131 2.398215316958 0.0171593382020529 -22.845378815222 25.6800860828058 -0.889614573002475 0.37447072212088 PPP1R3G other 1 1 1 2.398215316958 -0.889614573002475 0.000109835880225182 33.4248398636848 8.03668525130632 4.15903308621571 4.28864544055621e-05 -21.967526491582 28.0937122017052 -0.78193747888713 0.434931450368456 FAM228B other 0.810149452540942 1 0.417156542002903 4.15903308621571 -0.78193747888713 0.000700490472175604 9.02123540125682 3.13928914102546 2.87365546657165 0.00437766859351629 -6.34035132211914 6.6847784815844 -0.948475905310235 0.34372914994598 ZGLP1 other 1 1 1 2.87365546657165 -0.948475905310235 0.00133198550723991 32.7373438453019 77.4740961271561 0.422558577405937 0.67294997542312 -775.516448953696 228.570902056159 -3.39289227971438 0.000794062141320226 VAMP2 other 1 1 1 0.422558577405937 -3.39289227971438 0.156380064554759 64.2001878415299 45.0100422625125 1.42635253410993 0.154913359626813 -134.773760245901 122.66565308286 -1.09870821096809 0.272866931426451 RPL21P28 other 1 1 1 1.42635253410993 -1.09870821096809 3.87647066893756e-14 3.13289231376071 0.389799365449257 8.03719192859626 3.01854713725262e-14 -4.85065242857788 3.41600131867265 -1.4199796709864 0.156784540389627 SNORA81 other 5.00568657479907e-10 1 4.36663028874964e-10 8.03719192859626 -1.4199796709864 4.59033432386526e-08 120.61471865301 61.493910549768 1.96140914725848 0.0508550328142167 -442.106686043168 110.47363065765 -4.00192048918193 8.11441321722149e-05 MIR1282 other 0.000449118310246977 1 1 1.96140914725848 -4.00192048918193 2.47588399775675e-06 26.9848606074458 15.8506092042301 1.70244943016097 0.0898220707052827 -72.5186255052529 25.1052865844151 -2.88857987186935 0.00418350650253732 PPP3CB-AS1 other 0.0213198371046834 1 1 1.70244943016097 -2.88857987186935 0.60207266635734 -2.49773492881206 2.86258636899318 -0.872544827246752 0.383680812178228 -4.56419987485321 4.86538425959297 -0.938096485566187 0.349027061794847 EBF2 other 1 1 1 -0.872544827246752 -0.938096485566187 3.89310058460068e-16 45.4931190578101 5.2179118122502 8.71864467908503 2.92273133158572e-16 9.48982738916175 12.6847864979211 0.748126694187324 0.455034880566717 C6orf226 other 5.29889920569998e-12 1 4.34405557813586e-12 8.71864467908503 0.748126694187324 1.52473113233144e-11 478.837876390689 65.0283380425357 7.36352628414825 2.19079595205184e-12 346.797617945569 335.47376888486 1.03375479727774 0.302179273054811 PPP3R1 other 1.79689563945261e-07 1 3.06251366137327e-08 7.36352628414825 1.03375479727774 4.06206033882523e-34 335.655114136775 28.073560813064 11.9562714673722 1.2790729783664e-26 -88.6986503534781 74.8404370357222 -1.18517012816402 0.237015927118563 FANCG other 6.40871259656457e-30 1 2.00558643007851e-22 11.9562714673722 -1.18517012816402 4.5989300721713e-20 292.549425471116 30.3277519912264 9.64626146889318 3.96232252938957e-19 -166.380869475084 133.7218893948 -1.24423062094092 0.214485807314427 AP4M1 other 6.72823469558662e-16 1 6.03580590901914e-15 9.64626146889318 -1.24423062094092 0.202290844265258 5.55114042578544 3.24594870589464 1.71017503009353 0.0883696453159917 -6.32042389879653 12.1410522126114 -0.520582877671116 0.603079323996935 C2orf16 other 1 1 1 1.71017503009353 -0.520582877671116 0.0155257822919943 -21.8408481352158 8.21554384309962 -2.65847867801964 0.008314437422718 -46.125041518878 21.9706062484031 -2.09939775886842 0.0367033492152134 PLXNA4 other 1 1 1 -2.65847867801964 -2.09939775886842 0.0141681154092204 166.097915887301 101.06521319322 1.64347267115293 0.101713517710953 -636.073809306713 346.390910918068 -1.83628897080722 0.0676643505726276 CEBPD other 1 1 1 1.64347267115293 -1.83628897080722 0.013721384268023 3.74488758337832 3.0706154071628 1.21958861231617 0.223689102537621 -16.1453160663302 7.8405220926285 -2.05921440888607 0.0404362104127467 ZNF816-ZNF321P other 1 1 1 1.21958861231617 -2.05921440888607 1.14337938122118e-08 16.8406551549009 2.88759369543706 5.83207228271495 1.5439705048662e-08 -1.87677049827888 6.88901343754256 -0.272429501741306 0.785497729124117 ARIH2OS other 0.00011605300719395 1 0.000190031889738931 5.83207228271495 -0.272429501741306 6.7217548059439e-07 60.5008096229473 13.3109990149751 4.54517422433003 8.25418511878121e-06 -10.3317687048602 21.7430590339917 -0.475175488817292 0.635041837608304 ZBED8 other 0.00607041676524793 1 0.0853565283133165 4.54517422433003 -0.475175488817292 9.79822133758334e-05 13.3401883069642 10.2015752911194 1.30765964336674 0.192092949027495 -54.2825084375294 18.066590339348 -3.00457958131176 0.00290744609206995 HMSD other 0.727321969888811 1 1 1.30765964336674 -3.00457958131176 0.143479691139325 16.4313186813186 54.9405693550168 0.299074415759002 0.765110810682076 -242.925315425316 138.16970305861 -1.75816629874546 0.0798397828000948 NPTXR other 1 1 1 0.299074415759002 -1.75816629874546 6.60391040790511e-16 57.8866430700448 6.74022065074517 8.58824155313744 7.25197125167709e-16 -22.4475009659436 30.6008560369097 -0.733557941610137 0.463857028083982 FAM200A other 8.93376999981404e-12 1 1.07205891013542e-11 8.58824155313744 -0.733557941610137 7.64887399518997e-28 348.389582601168 64.5514486745852 5.39708387270221 1.47526113458263e-07 -609.677630225521 109.714629300674 -5.55694016478598 6.54205932738971e-08 PPP2R2A other 1.18817608641281e-23 0.00103495378559305 0.00172664563191551 5.39708387270221 -5.55694016478598 0.00290537778620632 4.89783204585099 1.82981233941017 2.67668543946413 0.00788871058154084 -3.49745470079387 3.84556623146405 -0.909477171964439 0.363906447127111 C19orf73 other 1 1 1 2.67668543946413 -0.909477171964439 0.856901494169929 5.32196648390254 11.1062663045566 0.479185924230818 0.632192805179806 -1.99465437803749 25.6463432743806 -0.077775391083923 0.938064114887341 ZNF880 other 1 1 1 0.479185924230818 -0.077775391083923 1.8676929140316e-14 2046.9315267778 250.273360268813 8.1787830897353 1.09218483984861e-14 852.353612065024 651.955307492258 1.30738043278395 0.192183540628142 TRIM16 other 2.42986848115511e-10 1 1.59087643772348e-10 8.1787830897353 1.30738043278395 0.080201322900133 4.29416607610672 4.810231342737 0.892715083774611 0.3727988792543 -25.8575547402216 15.4337923088232 -1.67538568764071 0.0950077420971965 XKR9 other 1 1 1 0.892715083774611 -1.67538568764071 0.0770862857433373 0.808893262494514 0.912147668894763 0.886800778074277 0.375975371455086 -4.3915416619928 2.58487290771022 -1.69893910408268 0.0904825269364313 LINC01465 other 1 1 1 0.886800778074277 -1.69893910408268 2.35039658780954e-06 211.841912486289 40.6779262809915 5.20778544665588 3.803205049879e-07 108.215295402638 154.084855092645 0.702309745740896 0.483093274292903 SLC12A8 other 0.0202815721562085 1 0.00433907664140695 5.20778544665588 0.702309745740896 0.374701092137203 -105.059700531763 94.041728876678 -1.11716045405262 0.264915181432093 -267.962464603804 223.433444751697 -1.19929433528446 0.231461053018695 APOL6 other 1 1 1 -1.11716045405262 -1.19929433528446 0.495508696225518 3.92959531343778 66.3766659383091 0.0592014566849437 0.95283544240165 -147.189039824729 134.262728777914 -1.09627624259147 0.27393474044306 FADS3 other 1 1 1 0.0592014566849437 -1.09627624259147 0.376391447747503 -0.170969810730487 1.05089135530085 -0.162690281795631 0.870882656642837 -7.40535029633107 5.29400305726911 -1.3988186663706 0.163002404947707 C3orf36 other 1 1 1 -0.162690281795631 -1.3988186663706 0.00113867999407268 582.852141537753 275.204155297587 2.11789004750854 0.0351190888533347 -605.69030989214 431.713618314522 -1.40299097410188 0.161794500324293 CCNL2 other 1 1 1 2.11789004750854 -1.40299097410188 4.34250518006412e-28 3728.75807293056 361.887163077618 10.3036483560784 3.1891043233162e-21 -1690.31095417906 838.347166206741 -2.01624222316775 0.0447611867361318 UBA52 essential 6.75172705396369e-24 1 4.90930719531296e-17 10.3036483560784 -2.01624222316775 1.02609975266669e-13 188.250367271615 26.004230448443 7.23922085080914 4.66425845458824e-12 -22.1123657685265 49.6646072341719 -0.445233879818384 0.656506177800663 PPT2 other 1.30745630484789e-09 1 6.46792719897751e-08 7.23922085080914 -0.445233879818384 5.50118519939578e-13 46.921972253239 5.91451339534695 7.93336139709368 6.08344103685259e-14 35.7757342796396 34.0218588634678 1.05155142825118 0.293966966382947 EXOC3-AS1 other 6.84457462508823e-09 1 8.75346330792719e-10 7.93336139709368 1.05155142825118 0.000425373040096311 58.916593886463 25.743857859334 2.28856895529748 0.0229038777100406 -115.18442503639 57.9460515025617 -1.98778729610762 0.047880051288341 TIAF1 other 1 1 1 2.28856895529748 -1.98778729610762 0.420501257788087 14.7118811237883 12.74253163159 1.15454931163883 0.249292105877783 1.09562422572796 22.2146884334153 0.0493198105844203 0.960700761502492 BTBD19 other 1 1 1 1.15454931163883 0.0493198105844203 6.58786302697451e-18 23.9763071481714 2.68380148133587 8.93371112390812 6.79030537959252e-17 -11.2567514402683 10.7976105059855 -1.0425224575408 0.2981090242941 FAM185A other 9.32050861056354e-14 1 1.01562597562565e-12 8.93371112390812 -1.0425224575408 0.4729349573515 7.46093598880358 7.9397530889774 0.93969370397191 0.34820842436793 -9.27052116954983 21.8421022356485 -0.42443355815904 0.671585161358942 RAB6C other 1 1 1 0.93969370397191 -0.42443355815904 1.35162413324541e-08 29.6012941190686 10.4485917334089 2.83304151165366 0.00497061567475638 -50.2312195652437 17.025770000839 -2.95030530559078 0.00346289150336766 URAHP other 0.000136527553699119 1 1 2.83304151165366 -2.95030530559078 0.651452261200173 -2.36119588913111 7.31115446961061 -0.322958008744803 0.746976088366971 13.8931796947991 20.0224211220522 0.693881105092603 0.488351115989397 LINC01124 other 1 1 1 -0.322958008744803 0.693881105092603 0.614812274269636 -14.2818772393193 14.5638519732079 -0.980638725633344 0.327645563391617 -9.5763785378486 38.8935131719989 -0.246220455722242 0.805697971120308 POTEJ other 1 1 1 -0.980638725633344 -0.246220455722242 0.0651754136867325 58.9426904715787 25.1631695300128 2.34241916151605 0.0198968604122804 19.7191491301029 101.435979257548 0.194399948365812 0.84601111455034 CYTOR other 1 1 1 2.34241916151605 0.194399948365812 0.118215766766618 13.4437046004843 7.43245767420861 1.8087832033185 0.071609506768403 1.63962873284908 10.5767045815718 0.155022646250881 0.876920589444717 DCDC2B other 1 1 1 1.8087832033185 0.155022646250881 0.00248709162925794 185.341074073201 92.987079825294 1.99319168234365 0.0472504671206135 -157.832780193708 145.468662780492 -1.08499505788318 0.278895258339284 C10orf55 other 1 1 1 1.99319168234365 -1.08499505788318 7.26475481209998e-24 7.81241610892051 0.694636240843034 11.246772986447 2.70624041705472e-24 -9.47737946648863 7.27114530956833 -1.30342319717047 0.193548934342257 EHHADH-AS1 other 1.10446067408356e-19 1 4.21929943423001e-20 11.246772986447 -1.30342319717047 0.454950779383808 -2.66791642523604 11.953893864173 -0.223183880963847 0.823561154736633 24.9865764568208 22.4737956741072 1.11180936318687 0.26720912320467 LINC00473 other 1 1 1 -0.223183880963847 1.11180936318687 6.5246049340307e-14 20.1804989777034 3.46165593593409 5.82972408326823 1.56341186169617e-08 -12.243888293535 5.54636005686144 -2.20755381331366 0.028107156599378 TH2LCRR other 8.36389106493396e-10 1 0.000192362195463097 5.82972408326823 -2.20755381331366 4.9201849599464e-17 68.8195548436434 14.9096861266811 4.61576147605747 6.10901665840176e-06 -73.0887178752282 21.3621438630636 -3.42141305403354 0.000721366491042936 NUTM2A-AS1 other 6.84004113131748e-13 1 0.0638086789970064 4.61576147605747 -3.42141305403354 0.145882892593145 13.7337409641909 7.27378461873416 1.88811487885119 0.060078669298146 0.790116822863952 13.6463100708408 0.0578996680247108 0.953871216378656 LINC01615 other 1 1 1 1.88811487885119 0.0578996680247108 3.33056006657159e-19 146.70922616006 28.9813469606184 5.06219487863754 7.63049722972358e-07 -242.553111230005 52.3759738106833 -4.63099955156406 5.63627093136645e-06 EXOSC6 essential 4.81399152022257e-15 0.0871254760570625 0.00852784370393907 5.06219487863754 -4.63099955156406 8.25620612723994e-24 365.618888490322 42.6730510696524 8.56791064443802 7.99538252031808e-16 -232.258188093808 78.5767425253049 -2.95581339502604 0.0033918569238481 VPS52 other 1.25477820721793e-19 1 1.18115785972659e-11 8.56791064443802 -2.95581339502604 0.0822261163283148 123.396614389603 55.6726033022794 2.21646926980601 0.0274837908636075 127.674615260044 109.366159866516 1.16740512253401 0.244065416366621 HLA-DQB1-AS1 other 1 1 1 2.21646926980601 1.16740512253401 0.279083130945714 12.6093287627084 11.9608861880944 1.05421358956324 0.292727599009279 40.5957243170921 26.0133717077377 1.56057141585444 0.119796228982216 ZNF844 other 1 1 1 1.05421358956324 1.56057141585444 0.00160120391239585 191.830943568797 91.8767402794392 2.08791629943935 0.0377425900740421 -261.485297130804 165.747812630795 -1.57760933903403 0.115826254040422 CKMT1A other 1 1 1 2.08791629943935 -1.57760933903403 0.00748671259440119 -8.18150767751724 58.3773106647985 -0.14014875958393 0.888646562793293 -288.520061862011 106.979761877195 -2.69695928275865 0.0074360865256729 TINCR other 1 1 1 -0.14014875958393 -2.69695928275865 0.275474587553648 -11.4160742562583 16.8481865198602 -0.677584750311335 0.498608844030735 -40.0280819379402 25.5563468256122 -1.56626775380215 0.118444315743016 HBD other 1 1 1 -0.677584750311335 -1.56626775380215 2.28303320495447e-05 13.9663005736745 3.00878367605405 4.64184271033769 5.37722824551103e-06 16.8862067483204 12.0690706348423 1.39913065879087 0.162913105867654 C1GALT1C1L other 0.181275156544906 1 0.0564608965778658 4.64184271033769 1.39913065879087 0.0114464187729523 7.62758518955605 3.17484028537857 2.40250989150042 0.0169533998433633 -5.34815007129857 5.94828731118625 -0.899107556765278 0.369390627254883 RAET1E-AS1 other 1 1 1 2.40250989150042 -0.899107556765278 0.00180788735623282 99.2269322897697 36.5851838855026 2.7122163059317 0.00711591079949711 -168.710965687994 117.404032359936 -1.43701167921356 0.151881099873857 NSUN5P1 other 1 1 1 2.7122163059317 -1.43701167921356 0.0162989442837547 22.3319053202015 9.54798471175189 2.33891297424418 0.0200669114600271 1.92877468528743 14.1539207473242 0.136271406327612 0.891707901710317 TSSC2 other 1 1 1 2.33891297424418 0.136271406327612 1.9271105239441e-05 7.65530746881971 1.74363323405895 4.39043447858536 1.61903658493939e-05 -6.65929830334354 4.86927270482342 -1.36761662511671 0.172556910556082 LGALS8-AS1 other 0.154014673073612 1 0.163360791420384 4.39043447858536 -1.36761662511671 0.0484733406314642 -1.12633460110898 5.81058181631815 -0.193841965695387 0.846444841467925 -21.1583912124168 10.0030416739498 -2.11519574766124 0.0353258762358906 LINP1 other 1 1 1 -0.193841965695387 -2.11519574766124 8.98990211826062e-05 16.9719457618061 4.87151934017398 3.48391222053528 0.000575403497180632 -13.6143766838108 12.7258352714311 -1.06982185400234 0.285644467406641 ENTPD3-AS1 other 0.670287101937512 1 1 3.48391222053528 -1.06982185400234 0.115738401360411 -996.853027705264 511.623926039842 -1.94840971457546 0.0523942238684601 -165.297146401407 940.044846090184 -0.175839639022444 0.860550765295409 HLA-DPB1 other 1 1 1 -1.94840971457546 -0.175839639022444 3.8406788579878e-07 50.6255974041513 11.3664350978532 4.45395561302356 1.23221763912433e-05 -81.9296699584016 39.1877175287629 -2.09069767582833 0.0374833463442159 OSER1-AS1 other 0.00353995370340736 1 0.125649232661508 4.45395561302356 -2.09069767582833 0.159747148033872 4.64353973033106 30.1725107201026 0.153899679526414 0.877803803443715 -86.260269668805 54.5798557700535 -1.58044150999999 0.115176530928581 C1QTNF5 other 1 1 1 0.153899679526414 -1.58044150999999 1.09440933248831e-05 68.1743314926471 23.9229269792476 2.84974875991497 0.00472442455738125 -63.8591996036689 38.9819281763296 -1.63817447189401 0.102590242601765 AFG3L1P other 0.0893256897176957 1 1 2.84974875991497 -1.63817447189401 7.06486794263388e-13 148.269136807817 43.0065998026348 3.44759031144641 0.000658410633426245 -272.838180549093 67.5564073163528 -4.03867214654337 7.05826960175307e-05 CPTP other 8.75761030168895e-09 1 1 3.44759031144641 -4.03867214654337 2.26808527535819e-22 59.4896107657708 5.37335448996751 11.07122392108 2.98304642824771e-23 19.5432239383988 16.7122915256381 1.1693922349558 0.243415445427503 EGFR-AS1 other 3.40643727506046e-18 1 4.63684736806823e-19 11.07122392108 1.1693922349558 0.0113377448507084 3.43774612123689 8.52070736604206 0.403457832026656 0.686927268234827 -31.8804917762332 13.7819159958238 -2.31321187749901 0.021454343386947 SLC44A3-AS1 other 1 1 1 0.403457832026656 -2.31321187749901 0.00656055909515299 7.4822338838263 2.34202874311613 3.19476603599279 0.0015642555090174 1.04955119516267 8.14864132898206 0.128800759880026 0.897610489577357 DNAJC27-AS1 other 1 1 1 3.19476603599279 0.128800759880026 0.370998713819778 -3.10881582775683 34.3159545157196 -0.0905938905570215 0.927883211640175 -135.107797497818 99.0300179362743 -1.36431155232911 0.173618368211194 HAGLR other 1 1 1 -0.0905938905570215 -1.36431155232911 0.859311040393004 -27.1377575512885 51.510695538867 -0.52683733479801 0.598735935295263 -37.4058145144053 192.298757172134 -0.194519273366504 0.845914510751085 LINC01133 other 1 1 1 -0.52683733479801 -0.194519273366504 1.52565001538774e-09 76.2415094339621 21.6755585814354 3.5173953717281 0.000510241601175497 -93.7093910806174 33.1777525446302 -2.82446470581637 0.00508513980435522 MSL3P1 other 1.63259808146642e-05 1 1 3.5173953717281 -2.82446470581637 5.61621030738945e-09 29.545013830075 5.20319425944358 5.67824539252057 3.49984368270173e-08 -8.8128458151743 10.2319261154639 -0.861308586059383 0.389829540250535 MDC1-AS1 other 5.80828469990217e-05 1 0.000423131101238639 5.67824539252057 -0.861308586059383 0.746542828079758 -21.4737250525884 29.090674448688 -0.738165252595471 0.46105042773922 -23.6915178800473 64.4458426222076 -0.367619025775347 0.713443210742124 PRR29 other 1 1 1 -0.738165252595471 -0.367619025775347 0.0900305873979587 -331.559314887393 231.462403154094 -1.43245430086829 0.153233776591591 -937.564037883524 441.661496479834 -2.12281135067506 0.0347295726204307 C4B other 1 1 1 -1.43245430086829 -2.12281135067506 0.0102124784957693 4.0672750281579 4.9122202824028 0.827991171879694 0.408398728059292 -24.1487231852724 10.206127965619 -2.36610037289571 0.0186751993505102 ADM5 other 1 1 1 0.827991171879694 -2.36610037289571 0.00644475444814423 12.2842813610969 3.99693531556999 3.07342510979443 0.00233032453500696 1.16704757067861 9.53560091970711 0.12238846618116 0.902681417671728 PRKAR2A-AS1 other 1 1 1 3.07342510979443 0.12238846618116 1.27204401676286e-12 200.46674068353 55.8867717703397 3.58701593119969 0.000397227200509283 -368.465651118529 95.8783697304906 -3.84305294462419 0.000151675503520296 ATXN1L other 1.56092521296971e-08 1 1 3.58701593119969 -3.84305294462419 3.73144778577472e-14 177.358722785765 23.5234052086042 7.53967043516695 7.11562554821078e-13 -25.9927719765566 44.4641617954553 -0.584578027044094 0.559317829205438 SMIM13 other 4.82065739444236e-10 1 1.00565135872863e-08 7.53967043516695 -0.584578027044094 0.755686339743829 -13.1336818167162 19.197374669157 -0.684139474436423 0.494471700173792 -0.94790072269842 35.3282179122628 -0.0268312634691204 0.978614064801601 HLA-DPB2 other 1 1 1 -0.684139474436423 -0.0268312634691204 0.000195390660874132 639.872277984831 181.727039924872 3.52106256861588 0.00050382601306696 -140.03094537714 397.400195805727 -0.35236758022534 0.72483548061105 HNRNPA1P10 other 1 1 1 3.52106256861588 -0.35236758022534 0.0809424714321974 -1.7717213261089 4.05115451232525 -0.437337386347179 0.662216285994115 -12.4662849134584 6.16756745579252 -2.02126446168824 0.0442390219730417 ZMIZ1-AS1 other 1 1 1 -0.437337386347179 -2.02126446168824 3.55693682793617e-15 113.410366345348 23.3289671455538 4.86135393983621 1.96996250797278e-06 -145.740883529481 40.1950948331038 -3.62583753402297 0.000343565662230959 SVIL-AS1 other 4.72610196327879e-11 1 0.0213957627990924 4.86135393983621 -3.62583753402297 4.57580094098592e-11 43.9327731576071 6.15809082134317 7.13415479442778 9.16538793622082e-12 -15.8501227249522 47.5180182834813 -0.333560264032774 0.738973211340091 LINC00885 other 5.28779556740333e-07 1 1.26268046662498e-07 7.13415479442778 -0.333560264032774 0.0111172950974344 -62.8356866723325 82.239587367985 -0.764056443901782 0.445493461829549 -677.389770058213 224.951618347965 -3.01126871205877 0.00284527725470197 SH3BP5-AS1 other 1 1 1 -0.764056443901782 -3.01126871205877 7.96339658260258e-05 4.49989364748231 1.07322166623931 4.19288371548671 3.74975692339856e-05 -3.21979220354235 3.37128270844517 -0.955064431552023 0.340409004519176 RASAL2-AS1 other 0.596936207831889 1 0.366463744123741 4.19288371548671 -0.955064431552023 1.24619645007856e-05 44.1657164571997 11.5096546300072 3.83727556359979 0.000154852713281813 -12.9216005176111 22.4686876614443 -0.575093690931681 0.565705084964108 NPIPA3 other 0.10120361371088 1 1 3.83727556359979 -0.575093690931681 0.00459493890665218 104.450041182652 31.6343956869965 3.30178715016791 0.00108920870466039 143.819361526883 137.721195531062 1.04427906664843 0.29728348380273 PCOLCE-AS1 other 1 1 1 3.30178715016791 1.04427906664843 0.0364160889370473 4.10848918980087 7.15982611075191 0.573825275397561 0.566561966712312 -26.2141817569539 12.4642672378558 -2.10314663964663 0.0363749563646361 LINC00240 other 1 1 1 0.573825275397561 -2.10314663964663 1.11752768686004e-22 4.52766829335051 0.41311210009342 10.959902390481 2.36538425898977e-23 -1.2648879873354 3.26760824102128 -0.387099032085948 0.698988965034474 OPA1-AS1 other 1.68254968533648e-18 1 3.67793598430319e-19 10.959902390481 -0.387099032085948 2.66642836953908e-15 173.077381825302 20.2609642732249 8.54240595320656 1.00499009572344e-15 53.1788892900389 44.9414183791558 1.18329352316801 0.237741415285161 NDUFAF8 other 3.55221587389996e-11 1 1.48346588029737e-11 8.54240595320656 1.18329352316801 0.0701226906966098 5.42455264125895 2.41799220237778 2.24341196631015 0.0256722965053633 2.20130411484764 6.62679383115218 0.33218237520827 0.740006453333329 POT1-AS1 other 1 1 1 2.24341196631015 0.33218237520827 0.243293134740895 6.93410368509927 4.30308205574816 1.61142725034409 0.108246372446703 1.84795887573622 11.5859008376395 0.15950066392185 0.873392809100285 PRRT4 other 1 1 1 1.61142725034409 0.15950066392185 0.142701557966062 2.46830149066539 2.27213972234139 1.08633349718558 0.278333746599427 -10.1636940509024 8.09899178401516 -1.25493324625447 0.210625508956244 LINC01752 other 1 1 1 1.08633349718558 -1.25493324625447 0.36999731314799 3.15032273165567 2.23015962297029 1.41259966291553 0.158925091616283 2.20933034135518 4.60138396657777 0.48014474718969 0.631513228461356 TMEM233 other 1 1 1 1.41259966291553 0.48014474718969 2.07108025296723e-07 11.6090820048369 3.3541219352998 3.46113892958375 0.000625092427755347 -17.3984575932982 6.46868560788897 -2.6896434063946 0.00759830933569984 LINC00092 other 0.00194401551052322 1 1 3.46113892958375 -2.6896434063946 0.0555666190646093 5.3480617639761 2.25853072383297 2.36793845996475 0.018587166368076 -1.8420017941328 6.32250963869345 -0.29134029039036 0.771013124488938 TAF1A-AS1 other 1 1 1 2.36793845996475 -0.29134029039036 0.485085994806598 6.51998000576343 10.3566309113544 0.629546428908198 0.529525697071975 -32.0607416841883 39.3177563397036 -0.815426531646031 0.415549600526042 LHFPL3-AS2 other 1 1 1 0.629546428908198 -0.815426531646031 2.99454548563222e-05 19.3720592328626 4.51988203539033 4.28596566927651 2.52802614174654e-05 -0.166982096042488 8.43493407258127 -0.0197964909512787 0.984220231042093 PPP1R26-AS1 other 0.234562747889572 1 0.251184677443936 4.28596566927651 -0.0197964909512787 0.47879911145078 21.1292777433352 51.5125161541332 0.410177551415141 0.681997413827919 -60.9508299047514 87.1426999657104 -0.699437014560426 0.484874473192452 SFTA1P other 1 1 1 0.410177551415141 -0.699437014560426 0.279339727572025 2.49009839030711 5.29894457590619 0.469923463934565 0.638787618151484 -8.29527892057314 7.78296011986514 -1.0658257003528 0.287451083222891 LINC01671 other 1 1 1 0.469923463934565 -1.0658257003528 0.833859745862163 -0.0124919514791439 2.19304521388784 -0.0056961668642472 0.995459362946682 -2.21381983608522 4.14843536490257 -0.53365176056858 0.594023163805973 LINC01504 other 1 1 1 -0.0056961668642472 -0.53365176056858 5.74192373636531e-06 21.0042666103816 5.98389231681481 3.51013445735969 0.000524343554170702 99.0278912692793 26.2575929430098 3.77140019971413 0.000199337076090709 BOLA3-AS1 other 0.047956547046123 1 1 3.51013445735969 3.77140019971413 0.659497559353204 2.78399587342646 3.43308657244841 0.810930867799516 0.418114360583417 -1.15576980698408 9.44435262141233 -0.122376816422939 0.902690965650474 RAB6C-AS1 other 1 1 1 0.810930867799516 -0.122376816422939 2.68306060905705e-14 42.6339670553643 13.3905314358813 3.1838890980176 0.00162330427137168 -85.6406417410095 20.3902946546576 -4.2000688656771 3.62785401354185e-05 NUTM2B-AS1 other 3.48046622206881e-10 0.549910111372673 1 3.1838890980176 -4.2000688656771 0.853576000005434 -3.69329728238335 19.3982296074997 -0.190393523383982 0.849142792758456 -18.9836714456854 34.3050185574785 -0.553378842045459 0.58045858833638 GBP1P1 other 1 1 1 -0.190393523383982 -0.553378842045459 1.44009736424985e-06 4.18667491258536 2.32148589347324 1.80344619984813 0.072420600991809 -28.1852834138101 6.75261687685244 -4.17397935168328 4.02827772704844e-05 MKRN2OS other 0.0126613360264847 0.610122944538757 1 1.80344619984813 -4.17397935168328 1.1442159491506e-06 7.22107880660019 1.34643460308742 5.36311142779755 1.77783309619087e-07 0.304384311726431 5.27481451678805 0.0577052161280123 0.954026762761296 C2CD4D other 0.0101480512530167 1 0.00207081999044313 5.36311142779755 0.0577052161280123 7.97687084928509e-11 4.87529569885064 1.0861437293627 4.48862850012608 1.05805932541718e-05 -3.7093896959458 1.70080145360191 -2.18096573711773 0.0300394718805348 MTOR-AS1 other 9.11676569364792e-07 1 0.10847224204177 4.48862850012608 -2.18096573711773 0.114241884524007 12.9317994677614 42.3339705994303 0.305470979562107 0.76024197118488 -104.126500765127 69.3649645611203 -1.50113968087415 0.134483641284153 ZNF469 other 1 1 1 0.305470979562107 -1.50113968087415 6.47600953026014e-12 68.0141416899975 9.83729564250851 6.91390643949925 3.46903711505736e-11 -24.8337897676723 32.4667236464909 -0.764899779789034 0.445006755285178 SBDSP1 other 7.73041257627153e-08 1 4.69846386863369e-07 6.91390643949925 -0.764899779789034 2.0641188153574e-05 349.082725305481 78.6493947257709 4.43846677425348 1.32487503141292e-05 8.85029634086264 174.756050979032 0.05064371900876 0.959647149182682 MCRIP1 other 0.164448346019524 1 0.13472654194438 4.43846677425348 0.05064371900876 0.159844502007985 9.03648254070448 5.11857639664375 1.76542886936878 0.0786137020456705 1.18330005511798 9.67593102260771 0.122293147021533 0.902757163808589 FAM225B other 1 1 1 1.76542886936878 0.122293147021533 2.05518824635429e-15 613.377237956843 94.4086120151965 6.49704751361147 3.86692964223582e-10 -851.543539056283 258.237799318909 -3.29751702230344 0.0011047597832904 FGD5-AS1 other 2.74717012890177e-11 1 5.07070483986383e-06 6.49704751361147 -3.29751702230344 0.0387799585913062 -1.70919075315166 3.88496229974248 -0.439950409110779 0.660321121112989 -18.3054864042986 7.32515843987148 -2.49898845937042 0.0130426931056517 DBH-AS1 other 1 1 1 -0.439950409110779 -2.49898845937042 0.206990508471646 4.60221636701795 6.60215212495948 0.69707820721356 0.486347018373569 -10.47820501982 11.1687295575283 -0.938173403326538 0.34898456419508 PROSER2-AS1 other 1 1 1 0.69707820721356 -0.938173403326538 0.160910344454416 36.5421982175729 188.877343620022 0.193470521753458 0.846734884804943 -926.154343918191 535.003028864444 -1.73111981418867 0.0845643656699855 MIAT other 1 1 1 0.193470521753458 -1.73111981418867 2.47589616055148e-10 46.0416186046561 7.14907497717109 6.44022041336527 5.55316657791666e-10 -5.50940660982178 17.0781269863294 -0.322600166530668 0.74725148646759 TRAM2-AS1 other 2.76384288402361e-06 1 7.23855263431437e-06 6.44022041336527 -0.322600166530668 0.98480956698917 -3.00584224050115 17.2636237663275 -0.174114211546014 0.861905221927973 0.417551048334251 58.3167909913198 0.0071600484395035 0.994292405238534 LINC00626 other 1 1 1 -0.174114211546014 0.0071600484395035 6.92016370798279e-05 12.8919341276161 8.35476677165757 1.54306331702164 0.123995353462583 -31.2517388860562 11.9406164582908 -2.61726343821696 0.00936737936657294 FAM229A other 0.52261076322686 1 1 1.54306331702164 -2.61726343821696 9.59943322029383e-16 86.1572894653642 22.549940567291 3.82073244087999 0.000165044642621318 -150.115758690117 35.3138129364983 -4.25090768193334 2.93232370820414e-05 ERCC6 other 1.293715615099e-11 0.445742526884111 1 3.82073244087999 -4.25090768193334 0.00165968076566542 5.34699872702942 1.55410247144221 3.44057024892791 0.000673122654199199 -1.79523825066796 6.20860862509693 -0.289153071013545 0.772687791828629 LINC01529 other 1 1 1 3.44057024892791 -0.289153071013545 0.0193541224317691 5.21053915589166 2.63052773423811 1.98079613002097 0.0486886021255858 -2.46636892569289 4.14376372892578 -0.595200182017199 0.552237492279453 LINC00115 other 1 1 1 1.98079613002097 -0.595200182017199 2.38630425827491e-28 426.662945614365 35.5022263015231 12.0179208478557 5.68670244536951e-27 23.2790929625307 67.278924853626 0.346008694597563 0.729603660174435 NOL7 essential 3.71332805630159e-24 1 8.92471081776291e-23 12.0179208478557 0.346008694597563 0.031913032601118 19.180866387532 14.6114856288899 1.31272526796369 0.1904069876963 -62.8221822995185 38.5060584770122 -1.63148825884173 0.103970658397266 CTAGE4 other 1 1 1 1.31272526796369 -1.63148825884173 0.00211116377062784 25.5350041642287 11.6573697840446 2.19046016702485 0.0293397858933123 -40.6850035955175 24.503936398706 -1.66034562502644 0.0979972609948045 NTF4 other 1 1 1 2.19046016702485 -1.66034562502644 0.741974135587412 12.0809429682811 16.5221361640487 0.731197397741375 0.465292673293569 -2.85070393248583 40.5266458932916 -0.0703414721265572 0.94397394504503 ELFN1 other 1 1 1 0.731197397741375 -0.0703414721265572 0.0583849705258348 0.596837018411648 2.04863817930319 0.291333542663279 0.771019923124128 -14.9909565158646 6.94780398951124 -2.1576539203604 0.0318368204152724 ABHD11-AS1 other 1 1 1 0.291333542663279 -2.1576539203604 2.35696020325983e-10 25.3569921643108 6.88378554834634 3.68358252682671 0.000277611754474373 -51.5695179935461 13.3126672942119 -3.87371792998745 0.000134463132114137 PIGBOS1 other 2.63484581122417e-06 1 1 3.68358252682671 -3.87371792998745 3.45230493893962e-08 4.51407513483647 0.748416305871447 6.03150292079798 5.32794801460469e-09 2.81943943441362 3.02567448434386 0.931838322001461 0.352252563425061 LINC01534 other 0.000340224651732499 1 6.69350109074787e-05 6.03150292079798 0.931838322001461 3.14091944680585e-06 7.30678945467679 2.59801189572279 2.81245419495817 0.00527464659070649 -7.92520765619358 3.94394646584526 -2.00946126546752 0.0454758833250532 LINC01772 other 0.0268171702368283 1 1 2.81245419495817 -2.00946126546752 0.0249090346286484 -4.64248641976953 11.1605051270368 -0.415974578831823 0.677761505666774 -41.4158636183018 17.2026147432977 -2.40753305449904 0.0167368903045964 ZNF503-AS1 other 1 1 1 -0.415974578831823 -2.40753305449904 0.0236379116304144 3.44239165733105 1.29207094216454 2.66424353725051 0.00817690182114447 7.01421305165745 6.05616602962621 1.15819365211333 0.247800934569713 LINC00937 other 1 1 1 2.66424353725051 1.15819365211333 5.1262706099225e-05 28.6917943443958 6.3416654147629 4.52433114456078 9.11261110725495e-06 22.0879983891345 14.854281284318 1.48697860006551 0.138195995852503 FTCDNL1 other 0.392313489777369 1 0.0938690070158333 4.52433114456078 1.48697860006551 0.000105149516277893 120.264856866921 29.5815851779296 4.06553117906097 6.2914319774578e-05 -13.2024268238324 65.7976190045454 -0.200652045219453 0.841121720168822 BAIAP2-AS1 other 0.77705492529363 1 0.602530440481134 4.06553117906097 -0.200652045219453 2.26182090705211e-15 12.0587579324508 5.12532594527387 2.35277874250521 0.0193436076817493 -37.1507026547207 7.53311659892647 -4.93165108582216 1.41821024940969e-06 AP4B1-AS1 other 3.01953091091457e-11 0.0221396802035347 1 2.35277874250521 -4.93165108582216 1.74332300019097e-23 47.6103007824557 4.54944348182822 10.4650823716406 9.50942938013724e-22 3.26508654328704 10.8184028452832 0.301808556214988 0.763029484422793 TEX22 other 2.64287766828951e-19 1 1.46759023623658e-17 10.4650823716406 0.301808556214988 0.000201077307152377 8.1224479455163 6.25954437610278 1.29761009068417 0.195541313534155 -24.3370698401255 10.0041985295388 -2.43268561377175 0.0156445009463888 ZNF32-AS1 other 1 1 1 1.29761009068417 -2.43268561377175 2.53009006464751e-19 40.0838476377676 4.09571150115044 9.78678493993251 2.51833657051671e-19 3.43476827716733 17.4444890130559 0.196897041500996 0.844070027030868 TMEM191A other 3.66281138659021e-15 1 3.84071510369503e-15 9.78678493993251 0.196897041500996 0.112029224368146 5.88284663807818 6.22441641193828 0.945124209041514 0.345462943044642 -19.7373071858445 13.8688807149565 -1.42313627115989 0.15588178042853 CFLAR-AS1 other 1 1 1 0.945124209041514 -1.42313627115989 0.000897225801624663 6.88605806198136 2.15931194435291 3.18900568303249 0.00159523793672787 -2.926043165641 3.91583724598281 -0.74723309009913 0.455570713872725 ZNF192P1 other 1 1 1 3.18900568303249 -0.74723309009913 0.000605974670416546 1.67022377672294 0.811435436553544 2.05835695790779 0.0405262598235109 -5.71439023519756 2.32899407694711 -2.4535872769106 0.0147833222650323 ST7-AS2 other 1 1 1 2.05835695790779 -2.4535872769106 1.8657221022031e-08 18.921983837396 3.45706135001098 5.4734301540052 1.00267809890266e-07 -7.33609323403213 9.28638598507174 -0.789983664885911 0.430225462833561 LINC01876 other 0.000186982669082794 1 0.0011855665841425 5.4734301540052 -0.789983664885911 5.58670119013772e-08 29.0837412436059 9.7667973395072 2.97781762358892 0.00316479636195361 -29.2027142252984 14.3750922177586 -2.03148013125246 0.0431783944794152 SLC16A1-AS1 other 0.000543530158788498 1 1 2.97781762358892 -2.03148013125246 1.04918126952027e-08 155.865337093351 32.6911392355243 4.76781601186837 3.03839993910872e-06 -243.431905398727 98.9629988969187 -2.45982749221544 0.0145227432145948 TMEM185B other 0.000106764685986383 1 0.0325199945482806 4.76781601186837 -2.45982749221544 1.61454560610354e-13 22.8104849617002 2.98949069401547 7.63022444169621 4.19146432013248e-13 -6.49657974547386 10.3628782472359 -0.62690881726867 0.531256693925236 PLCG1-AS1 other 2.0443376464483e-09 1 5.95816653106832e-09 7.63022444169621 -0.62690881726867 0.00203214958926084 12.0548014747817 5.82382893956415 2.06990995097529 0.0394012149004996 34.3438667234304 9.71643279949009 3.53461681176169 0.000479485103703255 KIF4B other 1 1 1 2.06990995097529 3.53461681176169 0.475632239316833 6.54576588128823 6.63278744726738 0.986880091263137 0.324591554811116 -4.61815016592144 15.3943921959891 -0.299989119877345 0.76441800391282 TEX41 other 1 1 1 0.986880091263137 -0.299989119877345 0.0267345666005089 3.55287386081066 1.65895043898241 2.14163954348748 0.0331208248937826 17.0494343625224 8.16374089785166 2.08843403726949 0.0376989980895116 LINC01535 other 1 1 1 2.14163954348748 2.08843403726949 4.04282200368705e-09 20.493149704466 5.05369730373088 4.05508056237105 6.54992209621362e-05 -18.4209756698409 7.92489397250766 -2.32444443215838 0.0208382540367157 ENTPD1-AS1 other 4.2126205278419e-05 1 0.626116752682026 4.05508056237105 -2.32444443215838 1.27205675767021e-09 16.8264266051633 2.90272739030165 5.79676433322065 1.86287411770094e-08 -5.85784787838205 7.12116504757892 -0.822596841843123 0.41145520843194 LENG8-AS1 other 1.36707939746817e-05 1 0.000228146193194834 5.79676433322065 -0.822596841843123 2.8845828826607e-10 15.1736234384878 2.20621442086548 6.8776739445549 4.16972810094905e-11 18.6679000555332 10.3409189028999 1.80524576498692 0.0721419306607345 FAM66C other 3.20880999867177e-06 1 5.63580450124274e-07 6.8776739445549 1.80524576498692 7.53954441179915e-05 37.5389964661762 26.4002372658496 1.42191890505224 0.156281384699282 -113.452816241166 39.8676085305157 -2.84573919587692 0.00479380594225368 HSBP1L1 other 0.566672157990824 1 1 1.42191890505224 -2.84573919587692 1.63142121544143e-17 93.6302146688368 12.0676245604692 7.75879413547123 1.71908075208953e-13 -72.7732981524007 33.2270435566027 -2.19018276568695 0.0293569955105335 SRRM5 other 2.2910048128444e-13 1 2.45828547548803e-09 7.75879413547123 -2.19018276568695 0.198216764077983 -19.8022052250515 10.9764099807794 -1.80406938696048 0.0723307284770923 -18.2467160698499 26.8544778162924 -0.679466426220353 0.497422309771763 FAM30A other 1 1 1 -1.80406938696048 -0.679466426220353 6.39712096348906e-14 29.1189770782744 9.01609249784747 3.22966707420385 0.0013921161589516 -66.0337296361312 15.1856591363696 -4.34842696277706 1.94255104795508e-05 CACTIN-AS1 other 8.20366792357837e-10 0.296744098085618 1 3.22966707420385 -4.34842696277706 2.28102813910457e-15 557.617737948085 63.1585706746173 8.82885302805285 2.34440670146413e-16 530.225947396602 128.041019330973 4.1410631543476 4.80324739379578e-05 ERVMER34-1 other 3.04448825726287e-11 0.725530518832852 3.48918049378906e-12 8.82885302805285 4.1410631543476 6.01755084003248e-20 1140.07014833127 115.1059447278 9.9045288323491 1.37804254209701e-19 453.194222087082 233.353642056458 1.94209191720023 0.0533058806005182 DANCR other 8.78923475695144e-16 1 2.1052355915616e-15 9.9045288323491 1.94209191720023 0.1930801012807 -4.96309232714205 2.7885170203732 -1.77983217992975 0.0762157231875647 -1.93828684658365 5.36900600216418 -0.361014095682208 0.718368115774686 LTA other 1 1 1 -1.77983217992975 -0.361014095682208 0.209220767197673 5.11859087331669 4.51386583678522 1.13397053842481 0.257801676264761 -21.3949359509818 17.2063045432381 -1.24343585208654 0.214774001008741 SLC8A1-AS1 other 1 1 1 1.13397053842481 -1.24343585208654 0.00689810672214119 178.636094367075 65.3667654557802 2.73282750219483 0.00669388745051465 -116.504967782167 136.705186092344 -0.852235171996095 0.394838882288138 LINC00511 other 1 1 1 2.73282750219483 -0.852235171996095 0.00151769538783494 -31.7587787731104 10.5827511773392 -3.00099456567734 0.00293983298703203 -51.1242351769409 15.3617298231302 -3.32802592973371 0.000994821709150903 ITGB2-AS1 other 1 1 1 -3.00099456567734 -3.32802592973371 0.328713397876731 -44.8979500842346 43.084106369212 -1.04210006584513 0.298297479981669 -137.284748490028 97.2190635362215 -1.4121175775251 0.159066834027152 C14orf132 other 1 1 1 -1.04210006584513 -1.4121175775251 0.00178568597903868 0.787999967944424 11.3215470991112 0.0696017921443159 0.944561941052414 -80.9181298734598 24.8127779142486 -3.26114754877942 0.00125162528217095 ZNF717 other 1 1 1 0.0696017921443159 -3.26114754877942 0.000613769945049391 5.1131583330359 2.3766979349993 2.15137071385448 0.0323441070634058 -16.1180924848615 6.82163381576758 -2.36279063347053 0.0188552012121891 ST7-AS1 other 1 1 1 2.15137071385448 -2.36279063347053 8.77869780556581e-11 5.77167459818375 3.22273713158615 1.79092316950563 0.0744555278620379 -19.5548990962739 4.63621879909909 -4.21785509779518 3.39655222700022e-05 KLLN other 1.00112269774673e-06 0.515324903880473 1 1.79092316950563 -4.21785509779518 5.07513473689573e-18 134.42559919399 23.4641178282818 5.7289858573743 2.67388571270448e-08 -103.555805392812 36.3775829826388 -2.84669285043577 0.0047541589838457 PARG other 7.19400348954969e-14 1 0.000325224719236246 5.7289858573743 -2.84669285043577 4.53120088902089e-06 3.19705609899122 2.46254783572161 1.2982716731894 0.195404897989494 -15.8022597669695 4.19995470408489 -3.76248337907078 0.000210185131990819 RBM26-AS1 other 0.0382342731015583 1 1 1.2982716731894 -3.76248337907078 7.97361777103598e-06 176.286316269006 46.1666205545169 3.81847997864245 0.000166868020676058 -36.2593815841923 72.5838182942745 -0.49955186205811 0.617800523977645 TP73-AS1 other 0.0658541091709861 1 1 3.81847997864245 -0.49955186205811 3.21347241836953e-08 4.40257615450701 0.727121212144662 6.05480362967476 4.91666875652389e-09 0.729674793871312 5.25967180801625 0.138730099615572 0.889771236643869 DLG1-AS1 other 0.000317426805486542 1 6.18516929570705e-05 6.05480362967476 0.138730099615572 0.000282179308568142 6.36998170555331 1.640971905155 3.88183471364895 0.000130176212200965 -3.15466545955875 6.84219011060066 -0.461060772729948 0.645123454381463 HPN-AS1 other 1 1 1 3.88183471364895 -0.461060772729948 2.41580964058304e-10 86.5236737167507 13.8852468803075 6.23133851796768 1.7609621557217e-09 -12.9374996817021 33.3984984539594 -0.387367704555245 0.698788056596661 LINC01806 other 2.6982177875672e-06 1 2.25420765553935e-05 6.23133851796768 -0.387367704555245 0.427118281538735 1.36456502045528 2.55475194749815 0.534128184848471 0.593777852517393 -3.72700385113361 5.03275461402994 -0.740549487698793 0.459735323825421 FGF7P6 other 1 1 1 0.534128184848471 -0.740549487698793 0.000311916509803807 311.398718744182 80.1799750836392 3.88374676369441 0.000129314955337397 81.4331047961779 215.097068501841 0.378587701651921 0.705290470467578 AKR1B15 other 1 1 1 3.88374676369441 0.378587701651921 4.1048311202954e-05 135.957941031084 59.9745244093463 2.26692820610173 0.0241857003969256 -222.908231804833 106.115048795169 -2.10062789713367 0.0366010293193006 SCAMP4 other 0.317098204042819 1 1 2.26692820610173 -2.10062789713367 0.49085655974979 -1.44817078715441 4.303410198027 -0.336517022666898 0.736739544053794 7.37002095101608 7.8444636728804 0.939518781442696 0.348294968502477 LINC01268 other 1 1 1 -0.336517022666898 0.939518781442696 0.735918757171416 -16.7941644983856 56.9075315204168 -0.295113213483181 0.768131705303412 -85.8335443110306 109.569665908144 -0.783369590475778 0.434089174742189 LTB other 1 1 1 -0.295113213483181 -0.783369590475778 0.0264636619050644 13.1937902690069 5.233450807559 2.52104983005674 0.0122768615727048 3.06146782762503 9.79197053040746 0.312650841637862 0.754787290483572 SLC2A1-AS1 other 1 1 1 2.52104983005674 0.312650841637862 1.9014488593997e-12 60.9969674065135 10.1995419094273 5.98036342692359 7.03575646951588e-09 -2.83336523260545 16.0076962819527 -0.17700018682887 0.859640944909489 DNAJC9-AS1 other 2.31938731869575e-08 1 8.78906698171924e-05 5.98036342692359 -0.17700018682887 9.48212012778366e-07 404.325754212856 86.1267363787554 4.69454400820173 4.24100978240797e-06 -168.03450805628 218.676190391812 -0.768417026815792 0.44290610354667 CERS6-AS1 other 0.00845236188190635 1 0.0448868475370059 4.69454400820173 -0.768417026815792 0.335729842789118 -1.81076255687932 2.55276152092232 -0.709334789810326 0.478724320951913 8.22602382779137 6.88085553035093 1.19549433809604 0.232935172815411 LINC01132 other 1 1 1 -0.709334789810326 1.19549433809604 0.241158362574799 -11.5357151503049 25.7889007677757 -0.447313177641103 0.65502281280656 -73.1443146261902 44.8112138790326 -1.6322770194006 0.103836313923494 SOX21-AS1 other 1 1 1 -0.447313177641103 -1.6322770194006 0.000717283407318681 1.60258048755245 2.54601406358492 0.629446832393349 0.529582959101802 -9.57923960879316 3.7413623851739 -2.56036133969629 0.0109948406760069 FAM212B-AS1 other 1 1 1 0.629446832393349 -2.56036133969629 0.692376115222111 0.530876098667433 2.08236981148532 0.254938433960857 0.798964011705109 -3.1326555686068 4.41487738250369 -0.709567966943233 0.478582140790967 SLC9A7P1 other 1 1 1 0.254938433960857 -0.709567966943233 7.06104395257353e-09 7.5817409982342 1.3959177264115 5.43136665921182 1.23763601666731e-07 -5.27983419331583 3.83898155032295 -1.37532158571371 0.170159264127524 DPY19L2P3 other 7.26016539203611e-05 1 0.00145583124640575 5.43136665921182 -1.37532158571371 1.02120450963509e-08 8.28999194366518 1.48307455811877 5.5897337718346 5.70147018176031e-08 -5.59103585142183 5.29633326358847 -1.0556427575771 0.292103904440605 SNAP25-AS1 other 0.000103999467261238 1 0.00068315015717852 5.5897337718346 -1.0556427575771 0.411549928462822 2.41814867714549 32.7300179453757 0.0738816789279257 0.941159037595462 -74.3778267383758 59.8048453971865 -1.24367559592211 0.214693719804827 TARID other 1 1 1 0.0738816789279257 -1.24367559592211 0.0879712261997335 117.261082957117 75.7061034868229 1.54889866941213 0.122586125847369 -342.284254494793 304.5847556391 -1.12377342646906 0.262114754238649 POLR2J2 other 1 1 1 1.54889866941213 -1.12377342646906 3.97266463305248e-08 28.9855751066447 4.83837398318001 5.99076780906341 6.84084588249701e-09 -2.3724359474118 35.0666177539927 -0.0676551118803488 0.946111588027956 MELTF-AS1 other 0.000390115666965753 1 8.55037326853302e-05 5.99076780906341 -0.0676551118803488 0.17109631520854 6.41530631441302 3.53668953206895 1.81392973746838 0.0707944297657303 11.3621077760407 10.408923188032 1.09157379402171 0.275989989969562 RNF144A-AS1 other 1 1 1 1.81392973746838 1.09157379402171 0.972462162550578 0.749439259442352 18.0569389365797 0.0415042251665447 0.966924262294512 17.0190015016442 72.1287253705269 0.235953171419808 0.813645927440455 NACAP1 other 1 1 1 0.0415042251665447 0.235953171419808 0.000160024238236093 3.11753981769006 1.6287916717257 1.91401998905546 0.056666917577074 -6.32204577569106 2.86562427089695 -2.20616702611618 0.0282082874255682 EFCAB14-AS1 other 1 1 1 1.91401998905546 -2.20616702611618 1.15642853111733e-15 13.0702895176156 1.60998447045961 8.11827055318387 1.72927791249008e-14 -12.1762358247585 7.42619685488513 -1.63963278414155 0.102254788517948 RALY-AS1 other 1.55551201720592e-11 1 2.51143031230934e-10 8.11827055318387 -1.63963278414155 0.0169621161782705 -17.4096624079871 6.08126127806236 -2.86283742992445 0.00452533501588079 -16.921786953211 11.3016302158928 -1.4972872612143 0.135478039510075 ORM2 other 1 1 1 -2.86283742992445 -1.4972872612143 0.0123167396273034 28.3011289173279 10.3257118855155 2.74084046031029 0.00653263135789437 -26.824228708929 29.1344296125035 -0.920705469978276 0.358017085305392 PCAT6 other 1 1 1 2.74084046031029 -0.920705469978276 1.20680215173215e-07 7.67442490262134 1.54286460670837 4.97414022543066 1.17973723171172e-06 -2.79264712741467 4.00716147143642 -0.69691404933917 0.486467477664388 BMS1P17 other 0.00114974613206852 1 0.0130160408774754 4.97414022543066 -0.69691404933917 3.67820458213937e-10 76.5350313238319 41.5119884421226 1.84368502199165 0.0663207454783273 -327.170096843339 72.2785971257913 -4.52651420826477 8.98678451966635e-06 C19orf24 other 4.07066901105365e-06 0.138378508033822 1 1.84368502199165 -4.52651420826477 0.81759476816412 -4.57487143428323 13.5728324742344 -0.337060922469042 0.736410835704229 -14.1199762860018 22.2423819432275 -0.634823029387871 0.526241505600502 CYP4F29P other 1 1 1 -0.337060922469042 -0.634823029387871 0.0235404379355995 53.1232979702367 23.0667116280636 2.30302865995018 0.0220347620368051 -38.371757603179 64.6245048863548 -0.593764821419639 0.553164701946164 GUSBP11 other 1 1 1 2.30302865995018 -0.593764821419639 0.000119063565073122 9.49817861102395 2.54888636150171 3.72640332440242 0.000236225969854107 -8.49071215843134 7.651918992178 -1.1096186678284 0.268143432345332 MIR646HG other 0.873212186246277 1 1 3.72640332440242 -1.1096186678284 0.012229519320886 2.99004566210045 1.73446531353214 1.72390052356331 0.0858789997663141 -4.94376712328769 3.14112194715823 -1.57388576644097 0.116693610031192 TSTD3 other 1 1 1 1.72390052356331 -1.57388576644097 3.39125195810065e-06 642.91644302006 125.316009253496 5.13036161021961 5.49364159292052e-07 213.699964205444 467.656774722241 0.456958983075502 0.64806391711435 OST4 other 0.028876510423227 1 0.00619463026017718 5.13036161021961 0.456958983075502 0.192801025221642 1.93679418898003 3.03117615040893 0.638957979633992 0.523389938661021 -7.61406198583807 5.68769491039329 -1.33869029647225 0.181793435565635 CCDC183-AS1 other 1 1 1 0.638957979633992 -1.33869029647225 0.0107980955214526 110.098045692265 38.1817673100748 2.8835240861995 0.00425280670377701 48.2559558216349 60.5757016687251 0.796622317072543 0.426378178453683 FNDC10 other 1 1 1 2.8835240861995 0.796622317072543 0.918667407431291 2.08955509430013 8.00593990805094 0.261000596844204 0.794289548281015 -2.51501072747941 15.1340756332634 -0.166181984841653 0.868137195929764 ZNF883 other 1 1 1 0.261000596844204 -0.166181984841653 0.000204651009149366 12.203096640199 2.94217046742332 4.14765112195766 4.48943361005661e-05 5.41271592095358 5.36313023604054 1.00924566115882 0.313750504614295 HDAC2-AS2 other 1 1 0.435924003536497 4.14765112195766 1.00924566115882 0.579230309050903 12.5758091993185 14.6107381399886 0.860723741595189 0.390148277516164 -11.3669505962522 40.0896596292244 -0.283538216621973 0.776979982674402 HOTAIR other 1 1 1 0.860723741595189 -0.283538216621973 9.07380829621325e-05 27.5105357512789 6.5875673199833 4.17612973272032 4.01400932428903e-05 -2.72903685879572 18.5895430628066 -0.146804945639353 0.883396353157501 SNHG26 other 0.676270932316774 1 0.391325769024937 4.17612973272032 -0.146804945639353 0.571258642010064 12.397699005968 18.2437937541385 0.679557068724023 0.497364987654477 31.1778097448979 30.0057018909144 1.0390628373982 0.299701679314826 PROB1 other 1 1 1 0.679557068724023 1.0390628373982 1.55305864806666e-10 7.54017781084464 1.85218155109602 4.07097123194148 6.14271304743489e-05 -9.14095760893181 2.95139487234034 -3.09716524027278 0.00215817132525646 TTC3-AS1 other 1.74998648464151e-06 1 0.588901899857583 4.07097123194148 -3.09716524027278 0.00712399484335887 814.720495280803 796.891127143141 1.02237365623781 0.307509183856612 -2620.60284854664 1431.10813590095 -1.83117039363126 0.0681648864718319 CES1P1 other 1 1 1 1.02237365623781 -1.83117039363126 5.7961178219928e-07 204.577943444009 54.0699683309529 3.78357801491251 0.000190015231727185 -136.524577574504 84.8602939153824 -1.60881575204816 0.10881240056207 DHFR essential 0.00526403420593386 1 1 3.78357801491251 -1.60881575204816 0.0129722831417843 2.82662165420784 11.4949386051755 0.245901413769638 0.805945373597063 -88.4640611378011 32.3272798217312 -2.7365142265491 0.00662137529358785 SRGAP3-AS2 other 1 1 1 0.245901413769638 -2.7365142265491 0.000225248216207589 32.275533648022 8.45838595519617 3.81580289892003 0.000168074178660712 0.539092415444741 16.03130304226 0.0336274858022236 0.973198867398973 SAPCD1 other 1 1 1 3.81580289892003 0.0336274858022236 0.0161612410949255 -0.723595875383943 2.55684371189128 -0.283003560999317 0.777388576937785 -19.2116608161474 6.91688982517586 -2.77749990266167 0.00585749134890157 WEE2-AS1 other 1 1 1 -0.283003560999317 -2.77749990266167 0.00135996898432948 12.973490172485 3.5741866837172 3.62977407743918 0.000339693475031073 2.1912197505764 11.6574716875365 0.187966980260319 0.851044776918597 LINC00954 other 1 1 1 3.62977407743918 0.187966980260319 2.18174599859566e-12 59.8641131983407 15.284305815674 3.91670475063057 0.000115314118706999 -81.9153009017389 24.0767475044862 -3.40225775456073 0.000775809694562763 LINC01128 other 2.65540305489078e-08 1 1 3.91670475063057 -3.40225775456073 0.045780600311146 3.36826107342402 1.94017459086014 1.73606081086278 0.0836896250350877 -6.578448831392 5.45147486300511 -1.20672827018515 0.228589116150424 LAMA5-AS1 other 1 1 1 1.73606081086278 -1.20672827018515 0.00021610934500394 10.473747939035 2.76898026449131 3.78252892349854 0.000191200812771351 0.720506225262461 4.98227409279759 0.144613927664885 0.88512358712786 UBAC2-AS1 other 1 1 1 3.78252892349854 0.144613927664885 5.62105555933961e-26 58.7189426325214 8.58298909199951 6.8413162364677 5.14771960691559e-11 -72.6101249631367 13.8068221993038 -5.25900340534536 2.92846034506137e-07 MED4-AS1 other 8.65867398360674e-22 0.00461173935140265 6.94221466188637e-07 6.8413162364677 -5.25900340534536 4.4016752620579e-07 1103.99463442511 222.804362177916 4.95499560077525 1.27305970854984e-06 -432.581010367483 593.123330586741 -0.729327254653019 0.466429059370998 RPL41 essential 0.00403752641533406 1 0.0140151143314252 4.95499560077525 -0.729327254653019 0.502661857599508 -67.8207950227034 375.899164536233 -0.180422840541233 0.856954975398655 -677.36963965972 638.412180854496 -1.06102242402875 0.289620906479125 VIM-AS1 other 1 1 1 -0.180422840541233 -1.06102242402875 0.0241464666382671 -28.2752624818282 10.3084705903254 -2.74291537566831 0.00649411926532785 -25.5832996177188 19.1576249360535 -1.33541081961431 0.182858365209814 ORM1 other 1 1 1 -2.74291537566831 -1.33541081961431 0.460835211926181 -274.523684122805 221.281331774964 -1.24060932714372 0.215827035018835 -172.62172612103 407.437128664036 -0.423676965049914 0.672138732943968 HLA-DRB6 other 1 1 1 -1.24060932714372 -0.423676965049914 0.330648170104383 -123.601802149049 96.8365265591349 -1.27639648530319 0.202963146043759 -238.054430418197 177.830637634284 -1.33865813891848 0.181860369442547 SFTA3 other 1 1 1 -1.27639648530319 -1.33865813891848 0.82744983513183 11.6166090708875 19.3234959396501 0.601164981076291 0.548234469225932 5.89917455997414 38.1142239218319 0.154776195156766 0.877113394878787 RALGAPA1P1 other 1 1 1 0.601164981076291 0.154776195156766 0.801881774196387 -0.985987625480846 4.72869365667007 -0.208511630710114 0.834986132380544 3.87968072518002 8.48212361703587 0.457394975638871 0.647753642060799 PATL2 other 1 1 1 -0.208511630710114 0.457394975638871 0.0752623825644091 14.4932769394418 26.7242311560546 0.542327180707617 0.588035548402005 -57.1206397959137 37.2421530891893 -1.53376308988147 0.126245989786797 NKX1-2 other 1 1 1 0.542327180707617 -1.53376308988147 2.92670432811579e-05 12.07265625 3.7744303864763 3.19853726624713 0.00154406072433184 -24.7087402343749 11.7880157763719 -2.09608985117764 0.0369948690925998 ACVR2B-AS1 other 0.229508934215774 1 1 3.19853726624713 -2.09608985117764 2.69784626446283e-07 44.5294800338009 8.3758478505186 5.31641462792853 2.23162175445966e-07 -84.4845690469967 53.9422700812716 -1.56620344156278 0.118480966062598 MBNL1-AS1 other 0.00251196465684134 1 0.00258332534296251 5.31641462792853 -1.56620344156278 0.0141833301679268 5.88641212087064 3.11826195295257 1.8877221380638 0.0601517213936226 19.3004755484924 6.7118637027351 2.87557620406198 0.00435924888008816 ZNF492 other 1 1 1 1.8877221380638 2.87557620406198 0.0469512120920078 -21.8491241261061 16.6989150210932 -1.30841579219413 0.191832801267398 -79.3621554206235 32.1884896344458 -2.4655445571356 0.01429584891763 C2-AS1 other 1 1 1 -1.30841579219413 -2.4655445571356 6.6483007570983e-16 18.2691564934437 2.09223261159807 8.73189548435991 2.55385024706359e-16 -10.1915820934637 7.1783798306435 -1.41976077247365 0.156818224652937 UBE2Q1-AS1 other 8.99169478409886e-12 1 3.79961839758121e-12 8.73189548435991 -1.41976077247365 3.13840135429256e-08 34.9628318822853 11.8267625093016 2.95624705871852 0.00339247038050041 -77.6347166258932 24.0492467587947 -3.22815585055705 0.0014015903992029 ZNF688 other 0.000310387893939535 1 1 2.95624705871852 -3.22815585055705 4.3566662360145e-21 186.422878516712 19.6299370856433 9.49686581792739 1.16795563862555e-18 17.9595865185475 43.7681850248466 0.410334276103797 0.681883778664677 PET100 other 6.45614369514989e-17 1 1.77389102394448e-14 9.49686581792739 0.410334276103797 0.259565354679045 -9.09728071091305 21.2657027500677 -0.427791209998177 0.669141636123174 -46.1836517825032 29.6824025839579 -1.55592700597167 0.120888191381521 EMX2OS other 1 1 1 -0.427791209998177 -1.55592700597167 0.220657512224458 5.83456482515682 12.3081950482713 0.474039028653215 0.635850979652717 -54.6291670246585 37.462006825059 -1.45825522054297 0.145919672944244 STEAP3-AS1 other 1 1 1 0.474039028653215 -1.45825522054297 0.905495326556677 0.776681598792731 4.82290852414276 0.161040085024375 0.872181814577448 -3.52014195328562 10.8350575124151 -0.324884473317482 0.745519165459119 LINC01315 other 1 1 1 0.161040085024375 -0.324884473317482 0.157809014445861 -4.3031601633649 3.69014025975307 -1.16612374068753 0.244589650619765 -10.3355431183095 5.3602101830329 -1.92819735894414 0.0548752365694213 GK3P other 1 1 1 -1.16612374068753 -1.92819735894414 0.0647100917552923 2.01787040611418 0.877360513857329 2.29993300843069 0.0222150097151848 2.5280834153135 2.35149085873821 1.07509812590556 0.283290582445213 PRPS1L1 other 1 1 1 2.29993300843069 1.07509812590556 6.94474208349143e-06 9.16492566711365 2.02160598037008 4.53348761138701 8.71530165012162e-06 -2.24139510243209 4.46598180917147 -0.501881825364603 0.616158154100831 TOB1-AS1 other 0.0576066355825614 1 0.0899244824259549 4.53348761138701 -0.501881825364603 2.58625066895131e-06 13.5938090624178 2.67171766278952 5.0880410201071 6.76859858020095e-07 16.512117514773 11.4363185614185 1.44383154649768 0.149941402071699 ALMS1-IT1 other 0.0222443420036502 1 0.00759166016755338 5.0880410201071 1.44383154649768 0.0117703403358433 -37.3848419925013 14.0095780288573 -2.6685202020714 0.00808665259494295 -100.879422792148 54.9318688582717 -1.83644621763051 0.0674075501798107 ANKRD36BP2 other 1 1 1 -2.6685202020714 -1.83644621763051 0.611429014691303 -2.05902789413656 3.68835229905581 -0.558251416130626 0.577130256307729 -8.92276178029126 9.32958291029234 -0.956394499742076 0.339719107236757 ANKRD66 other 1 1 1 -0.558251416130626 -0.956394499742076 4.12224970927708e-19 28.8031719355369 3.00661753209631 9.57992549037469 6.40974538082083e-19 2.8782600229286 8.35877093318325 0.344340100468871 0.730856599503499 PRRT3-AS1 other 5.95087968031239e-15 1 9.75114564784272e-15 9.57992549037469 0.344340100468871 0.287231808040311 0.144110234604685 6.26180114534667 0.0230141825426344 0.981655834029749 -20.3399792673276 13.7138074521195 -1.48317521143146 0.139185610141882 HOXB-AS1 other 1 1 1 0.0230141825426344 -1.48317521143146 0.000190104903449544 135.515545217292 33.0289038569548 4.10293801466127 5.41706670477686e-05 59.7102549041852 90.3382902534408 0.660962862333017 0.509203909591469 FEZF1-AS1 other 1 1 0.521717694337059 4.10293801466127 0.660962862333017 5.70610486352591e-05 28.198090383936 6.89114969527793 4.09192828930394 5.64241417521099e-05 -3.75204931782256 18.6279850206695 -0.201420030865351 0.840520699732283 TPI1P2 other 0.434691068503404 1 0.542687395371793 4.09192828930394 -0.201420030865351 0.2015373273721 -0.309441950216293 6.10351461715328 -0.0506989774951368 0.95960287750783 -20.1994996246108 11.8870917905538 -1.69928019237326 0.0904181804654529 GOLGA6L17P other 1 1 1 -0.0506989774951368 -1.69928019237326 0.385961176329565 6.30308216647306 6.62331738205606 0.951650329115952 0.342122325624133 -3.74579442567414 10.9638477063636 -0.341649622103016 0.732879359972158 LRRC37A6P other 1 1 1 0.951650329115952 -0.341649622103016 5.32126388600651e-17 38.1035261975477 5.61533308748853 6.78562172606392 7.62870263241448e-11 -29.7938637726512 15.8914788794542 -1.87483266967501 0.0619239496910014 ANKRD18B other 7.39123553766304e-13 1 1.02316159705943e-06 6.78562172606392 -1.87483266967501 0.1031597247153 12.8628668529843 10.6162117258047 1.21162493601354 0.226715294565988 -37.1603085278499 26.040183246769 -1.42703713624829 0.154724600440342 PSMG3-AS1 other 1 1 1 1.21162493601354 -1.42703713624829 4.4287345035444e-06 3.31022993042395 0.827381131124348 4.00085257676302 8.14906118948813e-05 -2.51908716554591 2.04809217149323 -1.22996767460386 0.219775880645404 PPP5D1 other 0.0373918054134254 1 0.771797585256421 4.00085257676302 -1.22996767460386 1.05347218436631e-19 36.1698006553194 3.66868122371642 9.85907426938527 1.54218962154474e-19 0.303170884697608 15.6272321602828 0.0194001651468473 0.984537604372756 THAP7-AS1 other 1.53332876434516e-15 1 2.35507777106097e-15 9.85907426938527 0.0194001651468473 5.53388365681478e-07 9.03581794961108 3.46459371304729 2.60804547314831 0.00961879650151937 -12.890462737206 5.45839153182847 -2.36158631385094 0.018915263800695 ZNF32-AS2 other 0.00503362057423873 1 1 2.60804547314831 -2.36158631385094 4.02473958294908e-05 29.481976395279 9.11674020185985 3.2338287307194 0.00138127826949536 -57.2633033273321 27.4592280881145 -2.08539377522116 0.0380203412935376 GTF2IRD1P1 other 0.311112369761964 1 1 3.2338287307194 -2.08539377522116 2.38251763269768e-06 3.19668585382873 0.624323379561466 5.12024050112321 6.04836369463065e-07 -0.0935286935287004 2.82696342266607 -0.0330845078428694 0.973633282837028 HM13-AS1 other 0.0205420670291194 1 0.00680501399282895 5.12024050112321 -0.0330845078428694 0.903822007179848 -10.0636291366803 70.6714777854068 -0.142400151405329 0.88686897934593 -138.495227483837 308.889701667403 -0.448364664591383 0.654245681442809 PRB4 other 1 1 1 -0.142400151405329 -0.448364664591383 3.26602784485816e-06 11.8070708177254 2.29861210938056 5.13660863855241 5.37806772961603e-07 7.27537516284443 6.50780544772842 1.11794601441012 0.264587459498434 KLHL7-AS1 other 0.0278494194331056 1 0.00606914943287169 5.13660863855241 1.11794601441012 0.0415059308307776 17.0834850772785 12.3152515570479 1.38718117109851 0.166517957026329 55.2387058092024 21.7888442851724 2.53518291682837 0.0117974266868015 SETSIP other 1 1 1 1.38718117109851 2.53518291682837 0.000445267631288854 4.84749806235143 1.61316912866958 3.00495340271562 0.00290492738804517 -8.14550105793979 5.40619060565769 -1.50669882956316 0.133052626831982 FBXW4P1 other 1 1 1 3.00495340271562 -1.50669882956316 0.000421968694964432 10.9702890295862 3.8022618437758 2.88520083053835 0.00422376045164556 -19.607141317076 11.7434449214232 -1.66962432644507 0.0961399190576181 FOXD3-AS1 other 1 1 1 2.88520083053835 -1.66962432644507 0.83779510332352 1.23191804492717 4.21419575613232 0.292325776071161 0.770260406255859 -3.08857895169915 7.94532027765879 -0.388729320375396 0.697780503895883 STMND1 other 1 1 1 0.292325776071161 -0.388729320375396 0.00148751281869032 601.526395793889 236.048835630884 2.54831333603574 0.0113808180306698 -1482.27817269358 648.71174646302 -2.28495657859661 0.0230940338436601 MIR205 other 1 1 1 2.54831333603574 -2.28495657859661 1.29786190473435e-15 1033.10768422578 177.749945991571 5.81214063645775 1.71678497015998e-08 -644.319132671548 305.418338352923 -2.10962817801402 0.0358006208251682 HSBP1 other 1.7431583242487e-11 1 0.000210804026485944 5.81214063645775 -2.10962817801402 0.471005566031983 9.95422311821224 8.2334045381812 1.20900449772035 0.227722696366707 -3.86775208067249 27.5754075621926 -0.140260921690796 0.888558804846857 MIR92B other 1 1 1 1.20900449772035 -0.140260921690796 0.00317099749430795 21.7469255370994 8.24865551929225 2.636420624699 0.0088601080281313 -13.089771644387 16.1372993889296 -0.811150077153973 0.417988696445406 LINC01508 other 1 1 1 2.636420624699 -0.811150077153973 0.0131703154615564 28.4265527529154 10.1952802168014 2.78820710646771 0.00568110702957678 12.5381475454299 15.523177154025 0.807704983395028 0.419979425776709 LINC01468 other 1 1 1 2.78820710646771 0.807704983395028 0.000880375051023713 18.9064802457173 7.16130149618268 2.64008996909226 0.00876895022875758 -5.76444828377753 11.4638494786332 -0.502837052642881 0.61548723657056 KLF3-AS1 other 1 1 1 2.64008996909226 -0.502837052642881 0.0663823622238124 6.46956336685883 3.57406763232503 1.81014016308645 0.071377579774073 -10.167878457026 10.7569999295507 -0.945233663997127 0.345378496471386 APCDD1L-AS1 other 1 1 1 1.81014016308645 -0.945233663997127 0.751162351024769 -1.95709955976308 5.77063094501794 -0.339148280042537 0.734765619407095 -7.34028503076148 9.81980935480322 -0.747497712587575 0.455423462604192 LINC00704 other 1 1 1 -0.339148280042537 -0.747497712587575 0.851933297863169 -3.95346109907293 6.99009753273627 -0.565580248423995 0.572148855483767 -4.58297014183125 21.2072714367157 -0.216103714969048 0.829070078098035 RPL13AP17 other 1 1 1 -0.565580248423995 -0.216103714969048 3.48110729571409e-06 11.6520896705441 2.28118876198591 5.10790245187787 6.13738550434866e-07 8.25351778709681 10.5405488396553 0.783025429951592 0.43429339685958 LINC01816 other 0.0296102986573441 1 0.00690271747674093 5.10790245187787 0.783025429951592 0.511836462660436 -510.110874944966 690.007304265449 -0.739283297135539 0.46037016667912 743.905524263538 1355.48626561656 0.548810816556052 0.58358384605206 HLA-DPA1 other 1 1 1 -0.739283297135539 0.548810816556052 0.502358741842714 0.368971560020714 2.60663596594049 0.141550858977574 0.887546988191109 -6.3080472633277 6.49062538634851 -0.9718704882576 0.332039569988247 LINC00689 other 1 1 1 0.141550858977574 -0.9718704882576 0.609694156813497 3.17040168070162 7.2426654974845 0.437739625252989 0.661925004982491 -14.9059174340006 20.9994789560356 -0.70982320395699 0.478426343461227 LINC01305 other 1 1 1 0.437739625252989 -0.70982320395699 2.56136339506755e-08 10180.3083699516 1902.58951608116 5.35076446280459 1.86590284950674e-07 -821.343424899631 3508.80426640818 -0.234080718825735 0.815099054831044 RPS18 essential 0.000254625135103665 1 0.00217116455568604 5.35076446280459 -0.234080718825735 0.163962505419443 9.70536708022764 5.5557690340221 1.74689894788543 0.081783568745027 1.11330131538806 10.5023806982712 0.10600466193073 0.915656788578953 FAM225A other 1 1 1 1.74689894788543 0.10600466193073 0.32583977781051 6.76912050419371 5.32224566345398 1.27185420069481 0.204527472409398 -5.16813960100457 15.5274938428583 -0.332837974582845 0.739516804329595 LINC01249 other 1 1 1 1.27185420069481 -0.332837974582845 0.000111755620080876 39.5181440965673 10.4059334738685 3.79765488562901 0.00018203410964316 -69.2072682006788 46.2570761655376 -1.49614445913119 0.135833544471923 FAHD2CP other 0.823638919996053 1 1 3.79765488562901 -1.49614445913119 0.0924313328302249 8.55973499414947 8.59822803327813 0.995523142794111 0.320366688995367 -33.2977205031578 23.0807553373655 -1.44266164674655 0.15026634935891 LINC-PINT other 1 1 1 0.995523142794111 -1.44266164674655 0.644297272768128 5.13828525870347 7.33430841431821 0.700582109237783 0.484183165313979 13.4492533270642 17.1410453222004 0.78462270382339 0.433380973022066 TSPAN19 other 1 1 1 0.700582109237783 0.78462270382339 1.2956284433527e-05 8.11957997120316 2.06618320887324 3.92974830902389 0.000108281898928248 -7.73654366769656 4.51947791454276 -1.71182243037452 0.0880862465185714 ABCA9-AS1 other 0.105062510471471 1 1 3.92974830902389 -1.71182243037452 7.82852028782189e-09 8.06227192466155 1.28600558774533 6.26923553170293 1.43779075110116e-09 3.39979025094977 3.87400026898503 0.877591640395134 0.380948487432414 DBIL5P other 8.02971325921891e-05 1 1.84784867331521e-05 6.26923553170293 0.877591640395134 2.00687249180114e-07 27.1172711117938 4.85833875507312 5.58159331386222 5.74463781763746e-08 14.890700197428 7.71972852520371 1.92891500637777 0.0547779712895906 PIK3CD-AS2 other 0.00188485464429963 1 0.000688150164174791 5.58159331386222 1.92891500637777 0.00382159363144993 13.8155560296788 4.61326848532813 2.99474354757745 0.0030026002024378 -1.2075301780098 8.77362616536659 -0.137631824658367 0.890634364577551 PCAT7 other 1 1 1 2.99474354757745 -0.137631824658367 0.49033457003932 -6.10684234665165 8.78913736261014 -0.694817033197224 0.48777416238649 -19.8268590405697 16.8429369608333 -1.17716162488022 0.240179293522303 CYP21A2 other 1 1 1 -0.694817033197224 -1.17716162488022 0.0827453137429357 33.5393749881658 15.3131913275343 2.19022764561554 0.0293537054577253 30.5686658245174 42.1604268793181 0.725055889780684 0.469038746960283 IPO9-AS1 other 1 1 1 2.19022764561554 0.725055889780684 0.317505943581464 19.130478880942 15.4983045297007 1.2343594645647 0.218134347913422 -43.5509181611658 68.9425151136955 -0.631699004443695 0.528114119994492 PRH1 other 1 1 1 1.2343594645647 -0.631699004443695 7.20999438503833e-08 20.5130697104002 3.94636020329583 5.19797196750275 3.98067778226394e-07 -3.59896790789125 6.93434551982371 -0.519006140897166 0.604181596709447 TRAF3IP2-AS1 other 0.000696701757426254 1 0.0045351861973333 5.19797196750275 -0.519006140897166 6.99095140860204e-09 43.3353436218665 7.72558840760002 5.60932596140321 5.03934701549778e-08 -12.7009581246339 18.6839008150862 -0.67978085788052 0.497227790178968 DARS-AS1 other 7.1901935237472e-05 1 0.000605326363501593 5.60932596140321 -0.67978085788052 0.00252817044560727 91.5408698356046 424.111069196319 0.215841736951295 0.829272883819007 -2369.25069829546 780.944072453977 -3.03382890256214 0.00264824483743612 TAPBP other 1 1 1 0.215841736951295 -3.03382890256214 0.401659435947126 12.2820319352619 17.0265111479124 0.721347540230974 0.471313024341396 37.8110009714509 28.0073792978539 1.35003709448632 0.178122325359784 PPP1R2P3 other 1 1 1 0.721347540230974 1.35003709448632 0.266788357534372 7.43854637665737 5.44763243781758 1.36546407298312 0.173252216601211 0.826619887107603 8.59842766604632 0.096136168054513 0.923484274547246 LEF1-AS1 other 1 1 1 1.36546407298312 0.096136168054513 0.00026489217907337 28.9169801373906 7.15425382592584 4.04192817881303 6.8998249924349e-05 7.5103824316785 13.6134078781756 0.551690105731631 0.581611984624627 ZBED9 other 1 1 0.658105307778441 4.04192817881303 0.551690105731631 1.33625450278773e-05 7.44101468502208 2.68330870168734 2.77307440636367 0.00593692223052306 -11.0677260308791 5.68944348688291 -1.94530907221345 0.052768011533844 TMEM253 other 0.108263339815861 1 1 2.77307440636367 -1.94530907221345 0.0864366909328244 18.7978168496806 10.0445292522533 1.87144826577748 0.0624189963166194 28.2960049185967 14.4176967628212 1.96258843448305 0.0507727750579098 LINC01697 other 1 1 1 1.87144826577748 1.96258843448305 0.000106149208022866 196.807230008617 55.5539500906685 3.54263251645313 0.000466039773718086 -175.045682708157 136.64248628671 -1.28104872404669 0.201267687571962 TMA7 other 0.784230348872932 1 1 3.54263251645313 -1.28104872404669 0.0121472338266243 22.3961424772073 26.0635178843167 0.859290851550159 0.390936733092031 -64.6532741704569 37.3044141706795 -1.73312664486963 0.0842064832362353 LINC00865 other 1 1 1 0.859290851550159 -1.73312664486963 0.736507981299777 -6.08724630703106 8.2422339023444 -0.73854326134807 0.460818828157973 -7.71337529653304 22.6925983179745 -0.339907100476166 0.734187858429423 ASCL5 other 1 1 1 -0.73854326134807 -0.339907100476166 2.42206083245509e-05 1.25474977700062 2.49056218720428 0.503801825727192 0.614809942334788 -13.756069558152 3.84438867443693 -3.57822029016533 0.000409699585062613 GNG12-AS1 other 0.191633453063846 1 1 0.503801825727192 -3.57822029016533 4.84992135821771e-08 95.0187258560855 19.1874584723088 4.95212672346448 1.29550115023433e-06 -124.166547114128 64.8271765434196 -1.91534713888032 0.0565045526801978 SMIM26 other 0.000473546321416377 1 0.0142543991560283 4.95212672346448 -1.91534713888032 0.0447129091426427 17.0985294099516 7.74983459678741 2.20630894716638 0.0282044543280525 -3.9420949004011 14.5898038797612 -0.270195194732502 0.787216498749896 C9orf172 other 1 1 1 2.20630894716638 -0.270195194732502 7.11228897916279e-05 14.6988615191177 4.29457772189524 3.42265583975295 0.000715948179304528 -22.0388196071707 12.0246076186926 -1.83280987671571 0.0679278785076743 MHENCR other 0.535839851690125 1 1 3.42265583975295 -1.83280987671571 0.373738571882583 -64.4098896260645 67.2108889194365 -0.958325215773749 0.338746712456845 78.2031437087871 132.032568738038 0.592301918051352 0.554138671649467 HLA-DQB2 other 1 1 1 -0.958325215773749 0.592301918051352 5.54627044202538e-07 39.2341241636233 8.78026402964041 4.46844468812974 1.18196425641044e-05 -0.460934461325103 14.9761531007804 -0.0307778945783535 0.975470557589809 IDI2-AS1 other 0.00504433296702208 1 0.120678550579506 4.46844468812974 -0.0307778945783535 0.000710533192280128 142.64441736122 37.5355959345235 3.80024384347185 0.000178819100445214 36.0015292370821 151.258452285677 0.238013338713047 0.812051944222832 LINC00665 other 1 1 1 3.80024384347185 0.238013338713047 0.00386145093874768 6.74763056065168 2.03871944840185 3.30973963383787 0.00106755866765552 3.69116721093773 5.90256967613956 0.625349197631472 0.532296779779604 BMS1P22 other 1 1 1 3.30973963383787 0.625349197631472 0.0212006661803265 10.4380786845403 5.93424855149307 1.75895542526847 0.0797136256988363 -26.3592447442371 16.6174193147796 -1.58624177707263 0.113850584262812 SLCO4A1-AS1 other 1 1 1 1.75895542526847 -1.58624177707263 0.718408094220179 3.86074873318145 24.0460838593456 0.160556236756238 0.87256166560668 -30.9549907291356 46.298289602009 -0.668599012949117 0.504316234955808 TNF other 1 1 1 0.160556236756238 -0.668599012949117 0.00409313760691476 47.4772425553269 18.0054790494291 2.63682195985962 0.00886276565269059 -26.7402954569605 35.541695236204 -0.752364097414294 0.452499894898469 COL4A2-AS1 other 1 1 1 2.63682195985962 -0.752364097414294 0.0275606336684303 10.4040789909864 4.64694621142684 2.23890669648871 0.0259798133901053 -10.7858008808348 13.153069573958 -0.820021579007673 0.412929807667086 RPS2P32 other 1 1 1 2.23890669648871 -0.820021579007673 4.08376186636307e-06 2.79171902104268 0.580669238408739 4.80776117690182 2.79212809404403e-06 -5.33436761277839 4.28797512185976 -1.24402951537293 0.214783146960933 LMLN-AS1 other 0.0345772117224961 1 0.0299818714738448 4.80776117690182 -1.24402951537293 1.60886085115779e-22 82.3850039335631 8.56839934158771 9.61498182439957 5.17538918080963e-19 -74.2268996904616 28.8266710349384 -2.57493831322033 0.0105587315893939 PET117 essential 2.41892228971574e-18 1 7.87694233319226e-15 9.61498182439957 -2.57493831322033 0.000139943410663586 21.1059970660894 10.3774060033287 2.0338413144209 0.043011015082578 -62.0705815469017 24.3112810243179 -2.55315964160071 0.0112627462256386 LYRM9 other 1 1 1 2.0338413144209 -2.55315964160071 9.10783537506834e-08 5.31248590117116 0.908600803037062 5.84688664528339 1.43173898421706e-08 2.38853622874027 2.79972216141215 0.853133307890635 0.394336016957992 SMG7-AS1 other 0.000874170039299059 1 0.00017650478197428 5.84688664528339 0.853133307890635 0.0444186114729489 0.0634474081969594 1.50069759081746 0.0422786100178906 0.966307501541177 -7.08887055525533 3.12469434892342 -2.26866047160667 0.0240698813137008 SEC1P other 1 1 1 0.0422786100178906 -2.26866047160667 0.0442829249968962 2.79366213128215 2.76388498449518 1.0107736562679 0.313019784395275 -6.09168672474796 4.4891028927732 -1.35699423030706 0.175903948420064 DPYD-AS1 other 1 1 1 1.0107736562679 -1.35699423030706 1.2827150764793e-19 84.8924299001782 9.21318447114013 9.21423316401617 9.30261647905805e-18 -70.2828349902823 38.3060109744878 -1.83477300826472 0.0676435603979019 DLGAP4-AS1 other 1.86519599270855e-15 1 1.40209035572363e-13 9.21423316401617 -1.83477300826472 0.442577206168581 2.0369216015344 2.71125422510854 0.751283882813629 0.455112660507964 6.48183032503338 5.13840741482903 1.26144733216898 0.21152205834009 RPL23AP87 other 1 1 1 0.751283882813629 1.26144733216898 1.0333403106514e-17 100.232881497847 14.173812964385 7.07169494543954 1.29353882966386e-11 -67.4360882092261 26.0991896287527 -2.58383839377655 0.0102927441337261 HCG25 other 1.45659650189422e-13 1 1.77447656653288e-07 7.07169494543954 -2.58383839377655 2.38356582628245e-14 228.095052959741 30.0846400135071 7.58177770640876 5.3978037704055e-13 -115.582600956843 86.7662518770155 -1.33211471576153 0.183937550078128 SNHG15 other 3.09553693859301e-10 1 7.64976750341867e-09 7.58177770640876 -1.33211471576153 0.929630439993253 -3.94216130388083 10.4636389912982 -0.37674859646431 0.706654182104898 -3.4007565497595 38.6474768680898 -0.087994270916232 0.929945978526187 CYP1B1-AS1 other 1 1 1 -0.37674859646431 -0.087994270916232 2.2978291638216e-07 6.23227947044865 3.20208961864934 1.94631637857702 0.0526425579284535 -18.9523294686308 5.1304757861717 -3.69406859295847 0.000266573073760192 MIR3936HG other 0.00214961918275511 1 1 1.94631637857702 -3.69406859295847 2.50076349310067e-07 153.152611180851 37.5649354435753 4.07700983303686 6.0001978142961e-05 -149.483094660638 70.4867950689211 -2.12072480404982 0.0348532348528587 SNHG7 other 0.00233371249176154 1 0.57571898028171 4.07700983303686 -2.12072480404982 0.0178739835109547 6.38604139332119 2.66979980992873 2.39195514569 0.0174458381445063 -7.60541171117791 8.98080925308785 -0.846851491536017 0.397830669572928 LINC01271 other 1 1 1 2.39195514569 -0.846851491536017 0.0728094751333106 2.65037155742899 2.00160368553103 1.32412403943283 0.186581695214804 10.4925838665997 4.6983327726195 2.23325685395199 0.026351548588786 LINC01399 other 1 1 1 1.32412403943283 2.23325685395199 0.260581230838601 1.81154208050183 15.0238550260203 0.120577713067942 0.90411454236069 -49.5583190118468 33.0179424839577 -1.50095115817485 0.134528102068396 HOXB-AS3 other 1 1 1 0.120577713067942 -1.50095115817485 0.141975167958968 1.50771853335194 2.21645603362408 0.680238412348159 0.496932087236774 -3.32443061558155 3.05171702235799 -1.08936398467668 0.276957602063788 CTAGE7P other 1 1 1 0.680238412348159 -1.08936398467668 0.00506263214950509 241.532072385888 337.618517675788 0.715399362714546 0.474973694216655 -2254.09793051691 804.543707435103 -2.80170972650201 0.00544698617315611 GPX1 other 1 1 1 0.715399362714546 -2.80170972650201 0.0223843450419355 24.7469060095887 13.0152119671637 1.90138324846518 0.058304645936455 -27.6246205529187 33.7680783880716 -0.818069072081903 0.414031193658903 USP32P2 other 1 1 1 1.90138324846518 -0.818069072081903 0.408273212319133 -1.87924280857966 1.81884446043156 -1.03320698908678 0.302435032973278 3.67866042000999 4.94775583276361 0.743500800029424 0.457827417161373 CHRM3-AS2 other 1 1 1 -1.03320698908678 0.743500800029424 4.02131340052251e-09 446.764137095459 88.071699042924 5.07273212564818 7.31698318639484e-07 -632.132396685228 296.158313139049 -2.13444083329998 0.0337108196260894 GTF2IP4 other 4.19141495736462e-05 1 0.00818843588389447 5.07273212564818 -2.13444083329998 0.363045389389772 3.34499800568379 2.38737405302416 1.40112019792063 0.162403548123556 -1.88319414668195 8.09374221772074 -0.232672859602424 0.816203560227706 LINC01719 other 1 1 1 1.40112019792063 -0.232672859602424 0.328164504704223 5.24635360821278 12.8490897705724 0.408305467693769 0.68337185022563 -44.6780723529558 35.8189713100193 -1.24732985674712 0.213353411938448 HOTAIRM1 other 1 1 1 0.408305467693769 -1.24732985674712 0.000423667385978569 0.698666686852465 4.80591308425251 0.145376471568281 0.884522510656903 -38.0384894120218 10.6617524408112 -3.56775207670529 0.000426158000603679 TMEM238 other 1 1 1 0.145376471568281 -3.56775207670529 1.09874352169497e-08 13.4346702142133 2.24848947051835 5.97497581837295 7.27268611898408e-09 -3.99932253014425 9.2405830929396 -0.432799801692167 0.66550700957915 ZNF529-AS1 other 0.000111687278980294 1 9.08140315677542e-05 5.97497581837295 -0.432799801692167 4.32776720254803e-10 8.54567495214627 1.54765453640511 5.52169411915153 8.12904247377882e-08 -2.60011821671461 4.35483120314437 -0.597065212272112 0.550983418673833 B4GALT1-AS1 other 4.77006501064844e-06 1 0.000965161212911759 5.52169411915153 -0.597065212272112 0.855049353557983 3.98155120052062 13.1398404216326 0.30301366476001 0.762110216855845 -5.26512496146689 20.9836638113985 -0.250915426819164 0.802068244214469 TWIST2 other 1 1 1 0.30301366476001 -0.250915426819164 0.00587533529313887 -7.1209531867516 10.722847511877 -0.664091621079587 0.50720259941596 -49.9604337366433 16.3401766760789 -3.05752102483583 0.00245745320334462 LINC01137 other 1 1 1 -0.664091621079587 -3.05752102483583 0.0769342656632489 4.18282145474775 2.58566573398331 1.61769613131855 0.106913268793661 19.2996785673287 10.6926930407918 1.80494085949179 0.0722147217856992 ANAPC1P1 other 1 1 1 1.61769613131855 1.80494085949179 0.199855662009944 5.69175640576981 5.72794562621562 0.993681989528639 0.321264120242957 34.4825157126717 20.1936667786336 1.70759060702917 0.0888575828850486 SLC26A4-AS1 other 1 1 1 0.993681989528639 1.70759060702917 0.583025047932401 2.00078106906559 2.29595686395885 0.871436698342715 0.384322805504412 7.26008691663905 12.6331856729928 0.574683781633927 0.566004006627462 LINC01122 other 1 1 1 0.871436698342715 0.574683781633927 1.90259854750763e-05 18.6654162260824 4.34779859459948 4.29307287813821 2.45627439029018e-05 -2.75743542478351 7.68053702453467 -0.359015966718886 0.719862698639919 HIST1H2BN other 0.152188857815135 1 0.244251925370455 4.29307287813821 -0.359015966718886 0.414718390023417 34.5438329305468 32.6336669923731 1.0585335977909 0.290751374748204 72.8399129505742 62.4278402211559 1.16678572720973 0.244318837383382 LINC01503 other 1 1 1 1.0585335977909 1.16678572720973 0.302411265966622 38.7457099500309 25.6628884583325 1.50979536122523 0.132260685264263 18.7730812826438 38.1847351550885 0.491638378697569 0.623372970571144 LINC01694 other 1 1 1 1.50979536122523 0.491638378697569 9.71503574768524e-16 496.467760861199 69.0504303543649 7.18993000207731 6.22677482192426e-12 -187.452368339661 158.727084555427 -1.18097279279519 0.238641371113247 RPS28 essential 1.30880961592816e-11 1 8.60664815886371e-08 7.18993000207731 -1.18097279279519 0.00623563862695567 98.9097035350931 86.2661880766548 1.14656397529938 0.252565803452979 -254.983400914185 133.992894110099 -1.90296211308542 0.0580973961807141 UQCRHL other 1 1 1 1.14656397529938 -1.90296211308542 0.192057067480424 1.86787861769893 1.12443869784956 1.66116536301283 0.0978718122745911 -5.61626775551343 9.29609977477446 -0.604153127826093 0.546262629276534 TPRG1-AS1 other 1 1 1 1.66116536301283 -0.604153127826093 0.449568610115705 9.7026954897253 8.50876613622387 1.14031756595337 0.255164529530092 2.15818368980919 12.0596796938906 0.178958624490045 0.858104404273167 RPL13AP6 other 1 1 1 1.14031756595337 0.178958624490045 9.43055668664758e-12 303.243321438904 51.3828237258481 5.90164766064342 1.06390208472367e-08 -227.221742694571 98.185570400309 -2.31420708529953 0.021398874952831 TRIM26 other 1.11940707870507e-07 1 0.000131955775568277 5.90164766064342 -2.31420708529953 6.94213556071221e-07 35.3734171713366 6.76188004806373 5.23129912389763 3.40589658855453e-07 5.35902650274878 19.7866285585975 0.270840809836713 0.786722728560649 RNASEH1-AS1 other 0.00626250048931848 1 0.00389941100423608 5.23129912389763 0.270840809836713 6.3558797145246e-15 60.0257640723936 7.20061766639736 8.33619653943186 4.94671698547718e-15 -50.1543675524753 24.4117351976583 -2.05451874462764 0.0409527597997878 LIX1L-AS1 other 8.3853121073723e-11 1 7.24149899504004e-11 8.33619653943186 -2.05451874462764 0.141432282065716 10.1786504881692 5.13317493444415 1.98291517786962 0.0483790020149026 8.15176022369117 8.5538341707694 0.952994886380635 0.341435673798801 ZNF879 other 1 1 1 1.98291517786962 0.952994886380635 4.64496060101399e-14 29.5665184553611 3.61369771694582 8.18179072275855 1.1086171416498e-14 -0.315530812423884 15.6441725202657 -0.020169223524935 0.983923275714408 TATDN1 other 5.98503173440653e-10 1 1.61470086681293e-10 8.18179072275855 -0.020169223524935 1.50587256106272e-20 52.6748806999992 6.47559733653333 8.13436629279337 1.9438466518038e-14 -32.1154045877896 13.1083875361731 -2.44998894785236 0.014972571753813 RNF219-AS1 other 2.2160420608599e-16 1 2.81993833777178e-10 8.13436629279337 -2.44998894785236 0.438467916330681 -6.90338402449788 13.4257340659935 -0.514190433876064 0.607541006093733 -24.2968176526852 19.013795840517 -1.27785203209716 0.202403229212417 LINC01426 other 1 1 1 -0.514190433876064 -1.27785203209716 0.00154418145152339 32.7195169346366 38.6368981724103 0.846846369204679 0.398809615916932 -149.790134296777 63.5841722998528 -2.35577705706997 0.0201476787763543 ZNF37BP other 1 1 1 0.846846369204679 -2.35577705706997 0.00662396873473494 64.6398790756336 20.8495860828633 3.10029555592772 0.00215376127052243 11.8383471197003 62.7001365348787 0.188808952802119 0.850395127646183 ZNF736 other 1 1 1 3.10029555592772 0.188808952802119 0.522813984866895 -18.9628350397379 22.7537017707029 -0.833395604409033 0.405361023249785 -69.3321144730119 68.412310510606 -1.01344500654255 0.3117583268417 MAGI2-AS3 other 1 1 1 -0.833395604409033 -1.01344500654255 0.873642922849674 4.06667618197729 9.24110593502736 0.440063798702168 0.660239098152225 10.6502797587054 25.4444963775369 0.418569092533023 0.675860176847749 PINLYP other 1 1 1 0.440063798702168 0.418569092533023 0.011907849937046 4.85802906693293 2.02018538730178 2.40474418707753 0.0168572972676002 -3.76761036168968 4.27188906544316 -0.881954166873673 0.378586074442567 SP2-AS1 other 1 1 1 2.40474418707753 -0.881954166873673 0.470251403919025 35.1628490764275 32.2477057407529 1.09039847234746 0.276502671465133 112.122194885362 138.04141565065 0.812235910193191 0.417366560778334 RPL13AP20 other 1 1 1 1.09039847234746 0.812235910193191 0.676199212549136 -3.40958553419368 3.95692505432841 -0.861675540319873 0.389622304802624 -3.79520008639338 6.41291795058686 -0.591805495663027 0.554470602641246 C5orf58 other 1 1 1 -0.861675540319873 -0.591805495663027 3.92563579875607e-61 73.3367281197346 3.32609876446342 22.0488726622541 4.54791153545916e-62 5.62338266352545 30.5108892263107 0.184307399952021 0.853912214166975 FAM133B other 6.25903371753668e-57 1 7.25209973444318e-58 22.0488726622541 0.184307399952021 0.0806833928368576 9.90342353954903 4.66035427772086 2.12503662798621 0.0344817759707222 3.57392449578629 7.39029397431882 0.483597067749353 0.629059508546312 LINC01759 other 1 1 1 2.12503662798621 0.483597067749353 9.71047199994748e-05 34.1576086296329 8.0038736564048 4.2676346599124 2.79118505507218e-05 8.63908358742012 24.093865591361 0.358559466294928 0.720222511262127 CCT6P3 other 0.721002545996101 1 0.276355232302696 4.2676346599124 0.358559466294928 0.000256311706565743 17.6983279082032 4.72641459778764 3.74455679713063 0.000220721346590329 5.32249822698259 8.56632949479897 0.621327749558798 0.534906275525514 MCIDAS other 1 1 1 3.74455679713063 0.621327749558798 0.000494491022528322 71.4495988353547 21.5539047379691 3.3149259822741 0.00104263249580237 -49.4645774208236 44.86751458913 -1.10245860226025 0.271247706038493 MAPKAPK5-AS1 other 1 1 1 3.3149259822741 -1.10245860226025 0.02979026963812 62.4040074452984 27.9754508584612 2.23067030308197 0.026518619723027 -87.8285190155132 104.614899343088 -0.839541208441799 0.401902954888622 JRK other 1 1 1 2.23067030308197 -0.839541208441799 1.05670567298667e-10 18.9331516702181 2.83857863300629 6.6699408817033 1.43338157257444e-10 -14.9785415726006 11.3374305247756 -1.32115840003324 0.187562957683962 SDCBP2-AS1 other 1.20020630337826e-06 1 1.90711418231029e-06 6.6699408817033 -1.32115840003324 0.557643141913588 32.4339535479795 30.3431995353868 1.06890354493284 0.286078547407318 24.2963690172835 76.2770916243457 0.318527732244168 0.750333680681339 LINC01287 other 1 1 1 1.06890354493284 0.318527732244168 1.02559075159742e-05 819.889286877657 179.195730745026 4.57538404218045 7.26444791054894e-06 -756.92318835846 574.037049712843 -1.31859640198678 0.188425605551113 GAS5 other 0.0839035793881849 1 0.075484878238514 4.57538404218045 -1.31859640198678 0.994951971229231 -306.247952454906 3045.71892352234 -0.100550300321454 0.919981254088687 -248.104543420376 5853.99791808052 -0.0423820689539512 0.96622510293913 HLA-B other 1 1 1 -0.100550300321454 -0.0423820689539512 9.36411745127693e-09 660.594976150289 184.412908299286 3.58215150036136 0.000404104790691662 -1382.85074936599 375.699936238248 -3.68073192455658 0.000280772556548915 HNRNPUL2-BSCL2 other 9.56076391775375e-05 1 1 3.58215150036136 -3.68073192455658 0.979485941678638 -0.27956148776208 14.7761275681795 -0.0189198074036745 0.984919000416747 7.74896265398482 42.0669739603448 0.18420537358569 0.853990106463488 APOC2 other 1 1 1 -0.0189198074036745 0.18420537358569 2.30817770718766e-11 92.8702345725597 13.1536254001797 7.06042872190134 1.37571617628374e-11 99.622149349274 49.1994382039064 2.02486355507539 0.0438545969930849 GTF3C2-AS1 other 2.69802892193165e-07 1 1.88514387636161e-07 7.06042872190134 2.02486355507539 2.7428917496431e-05 45.5748115705847 19.0102079168568 2.39738627635799 0.0171897438276588 -134.742528300789 44.9946330039491 -2.99463556662332 0.00300169589808317 SEMA3F-AS1 other 0.215755865026926 1 1 2.39738627635799 -2.99463556662332 0.564785298633178 7.42565643649964 6.9534036874367 1.0679167743297 0.286511937215436 7.68576385466163 20.7111311870233 0.371093388635247 0.710858981349213 DPP10-AS1 other 1 1 1 1.0679167743297 0.371093388635247 0.000822546789818396 19.3077811129078 76.1462074032141 0.253561953659334 0.800031345765257 -363.942053963123 119.450793478836 -3.04679477937168 0.0025473535273348 ANKRD65 other 1 1 1 0.253561953659334 -3.04679477937168 0.286713718750197 74.6941551518671 65.9256620770407 1.13300576434985 0.258209542943329 -73.8143028244088 119.435649638713 -0.618025715501975 0.537075509502274 ZSCAN31 other 1 1 1 1.13300576434985 -0.618025715501975 0.0270852711567024 182.365969312031 76.9660582230197 2.36943366364951 0.0185163318855898 -86.945903177929 166.669711907272 -0.521665887478715 0.602329058010169 C12orf75 other 1 1 1 2.36943366364951 -0.521665887478715 0.00578895231084959 5.31259609361655 3.08881999535721 1.71994357120256 0.0865971208659909 -6.44369380425669 4.85628678456072 -1.32687670438713 0.185678878182212 SMIM1 other 1 1 1 1.71994357120256 -1.32687670438713 1.62972180770309e-13 196.252059308073 24.5486122063543 7.99442582164679 3.86462342020377e-14 70.1070840197694 93.0159054650822 0.753710708606576 0.451682153295255 HGH1 other 2.06339078073289e-09 1 5.57819744472212e-10 7.99442582164679 0.753710708606576 3.22271502456864e-10 55.7454975521863 10.6542303019558 5.2322407130577 3.34119543376865e-07 -43.5198773544354 22.1924117802586 -1.96102513712136 0.0508925470350371 NUCB1-AS1 other 3.57689140576873e-06 1 0.00382633701075186 5.2322407130577 -1.96102513712136 1.05814817371863e-11 129.678182204548 21.6360342085405 5.99362068642689 6.52176708715894e-09 -26.3549191632572 44.065175639446 -0.598089506754739 0.550279710656009 PPP1R3E other 1.25401140067395e-07 1 8.15873062603583e-05 5.99362068642689 -0.598089506754739 0.000104967069560873 62.8392541924099 14.4226457199352 4.35698521704326 1.91006492771455e-05 63.5513018534867 69.7649572876143 0.910934433622441 0.363186851443691 TSPY26P other 0.775811611124411 1 0.191655914846878 4.35698521704326 0.910934433622441 0.119083548279735 8.40078124999999 6.11465698864351 1.37387612512074 0.170607142192184 -18.9038574218748 19.0968346660975 -0.989894804683768 0.32310207907006 ITGA9-AS1 other 1 1 1 1.37387612512074 -0.989894804683768 1.07294265831606e-05 3.85718709781984 2.93000066884421 1.31644580795996 0.1891326602483 -14.4748914173914 4.37985412844085 -3.30487979574429 0.00107772416275787 SSR4P1 other 0.0876701446110051 1 1 1.31644580795996 -3.30487979574429 0.601247047996309 6.41094832637132 7.17038871487013 0.894086580421524 0.372065997633746 1.29741447066606 10.874407878137 0.119308976194879 0.905118642568842 RPEL1 other 1 1 1 0.894086580421524 0.119308976194879 0.76485769412356 -1.41352551732548 2.6939492793454 -0.524703834687248 0.600226096631714 -5.33606641423546 7.56271834445616 -0.705575187544443 0.481069792787166 SPAAR other 1 1 1 -0.524703834687248 -0.705575187544443 2.11098554965885e-20 23.0310670248675 3.65900677244968 6.29434938417681 1.31845387638429e-09 -40.1916747173604 9.95599616336174 -4.03693151924531 7.14381424507843e-05 SMIM27 other 3.10145996955878e-16 1 1.69737752045713e-05 6.29434938417681 -4.03693151924531 0.63640733257348 36.238976846853 40.2614870073011 0.900090372724718 0.368871291225228 -0.479658855041759 132.207242849566 -0.00362808303617332 0.997107884162719 MSC-AS1 other 1 1 1 0.900090372724718 -0.00362808303617332 0.356855857517812 -35.9857024531763 25.9007858977338 -1.38936720280464 0.165861594026623 -50.3715726682 58.1882288278687 -0.865666023573397 0.3874390389821 NFAM1 other 1 1 1 -1.38936720280464 -0.865666023573397 0.0115674147694415 11.7492634427514 3.94140400003904 2.98098429966453 0.00313329140603959 4.57347872777998 11.8265877851273 0.386711603623442 0.699272085241413 GNAS-AS1 other 1 1 1 2.98098429966453 0.386711603623442 1.94944762030495e-12 4.46469709444947 2.2888385742057 1.95063869718242 0.0521306877796129 -17.3541850580177 3.54664324064939 -4.89312961030726 1.70518712335891e-06 FAM21EP other 2.37676653867579e-08 0.0265906880016588 1 1.95063869718242 -4.89312961030726 0.0330641970717865 13.5221065734811 7.21598669997601 1.87390957546056 0.0620148940700214 -13.9641030640251 16.0034521169692 -0.872568178538072 0.38366810205752 DICER1-AS1 other 1 1 1 1.87390957546056 -0.872568178538072 0.16374581714248 4.74547715669572 29.9683594071885 0.158349581043713 0.874299709986745 -84.9228433040976 54.2105610395792 -1.56653688276894 0.118394207337255 MFRP other 1 1 1 0.158349581043713 -1.56653688276894 0.0715359130833074 177.955251685115 77.2231513782563 2.30442876921003 0.0219663188515615 19.022731020551 248.586083273844 0.0765237167343573 0.939059755211425 KIAA0040 other 1 1 1 2.30442876921003 0.0765237167343573 0.15375851720012 -0.171940344601286 1.23966100214863 -0.138699486636485 0.889789879558969 -4.36452502584295 2.35284025703922 -1.8550026984557 0.0646738306815592 IFITM4P other 1 1 1 -0.138699486636485 -1.8550026984557 0.112596941999738 1.2683349118398 3.21708714750693 0.394249472794882 0.69371394029846 -16.0657677880278 8.93101420306217 -1.79887383702954 0.0731764014721583 BHLHE40-AS1 other 1 1 1 0.394249472794882 -1.79887383702954 0.00542915743629447 1.98575274613117 16.3035399087513 0.12179887050574 0.903148574613451 -85.9359760809465 30.0674054523396 -2.85811079433393 0.004592505002463 B3GALT4 other 1 1 1 0.12179887050574 -2.85811079433393 0.0543130705456736 5.27384116530691 7.62983588170392 0.691212923459258 0.490023416684993 -26.5143336400874 14.6714283475604 -1.80720874695859 0.0718386472930872 GSN-AS1 other 1 1 1 0.691212923459258 -1.80720874695859 0.000434360014452321 15.090542978595 3.86503082243865 3.9043784310816 0.000119305426055207 -1.20232639025725 25.2015371689979 -0.0477084545357142 0.961983735700538 LINC00941 other 1 1 1 3.9043784310816 -0.0477084545357142 0.162005359355505 20.2155882335223 21.0279255490537 0.961368642206935 0.337217558182525 -27.9499027090851 30.5237556484511 -0.915677055962262 0.360644413972245 TSPEAR-AS1 other 1 1 1 0.961368642206935 -0.915677055962262 0.278525758773591 5.62936838823147 5.73329997775705 0.981872291711789 0.327054966765985 60.3536191147576 44.2141123613615 1.36503066309436 0.173396831791655 TM4SF19-AS1 other 1 1 1 0.981872291711789 1.36503066309436 1.1289184274803e-06 22.1625412973937 4.21790068089134 5.25440093878887 3.05579312813707e-07 7.54574032315394 9.83498388748752 0.767234640084561 0.443625039759366 LINC01564 other 0.0100157642886052 1 0.00350866166972699 5.25440093878887 0.767234640084561 0.736730436141531 -0.152301391809548 0.29304665717383 -0.519717212536587 0.603681822213208 -0.392100616332672 0.508415127550132 -0.771221380099493 0.441242709955799 APOA1-AS other 1 1 1 -0.519717212536587 -0.771221380099493 9.67708519662873e-14 82.8385443973737 12.8054529711605 6.46900539824216 4.56618417491841e-10 -93.8963747160306 36.0541531511316 -2.60431507910993 0.0097118678048847 TTC28-AS1 other 1.23402190427409e-09 1 5.97074242712332e-06 6.46900539824216 -2.60431507910993 7.61107831541356e-15 7.40454476036827 0.962762071019848 7.69093941613704 2.68650654921139e-13 -7.1517097584584 3.42666468615495 -2.087076038503 0.0378121977765897 UBOX5-AS1 other 1.00161790630842e-10 1 3.83230159245004e-09 7.69093941613704 -2.087076038503 0.00830939064987173 15.8268276590322 7.99302042050816 1.98008097394877 0.0487021122660133 -43.232952518635 25.5353344194771 -1.6930638858467 0.091588236191457 MORC2-AS1 other 1 1 1 1.98008097394877 -1.6930638858467 0.030482822907774 6.46922281484706 2.54480910921671 2.54212498352707 0.0115772866224303 0.662383958699383 7.65557931005857 0.0865230352756042 0.931114774827756 LINC01814 other 1 1 1 2.54212498352707 0.0865230352756042 5.86045430067714e-16 96.7246001279592 12.5083625565461 7.73279473557787 2.60405160969621e-13 -19.9449016314778 25.3407441245771 -0.787068506490067 0.431990256640577 MYCBP2-AS1 other 7.93915744112732e-12 1 3.71598164703649e-09 7.73279473557787 -0.787068506490067 0.146071049459434 16.6865792856664 8.48251764326429 1.9671729535295 0.0501870163450714 11.1436289859715 20.8065098482962 0.53558377004224 0.592687132653017 ELFN1-AS1 other 1 1 1 1.9671729535295 0.53558377004224 2.25335825150677e-08 22.9156510762838 6.40853150663063 3.57580376293289 0.000413080762711504 -54.9774801443235 17.533257045901 -3.13561136988957 0.00190298057626525 COX10-AS1 other 0.000224614750510195 1 1 3.57580376293289 -3.13561136988957 1.51321536539807e-10 90.9202664746061 20.7546155055328 4.38072516690894 1.69002476468316e-05 -113.594319916257 38.2168614127931 -2.97236130118815 0.00321976267428125 ZBTB22 other 1.70584768141325e-06 1 0.170253094794182 4.38072516690894 -2.97236130118815 5.55726651299204e-10 108.816382188766 16.4450388643639 6.61697324562544 1.97473086561226e-10 4.07860818433795 64.2556665489611 0.0634746848549172 0.949435657882038 TMEM147-AS1 other 6.08909691828537e-06 1 2.61533355841688e-06 6.61697324562544 0.0634746848549172 0.00164127974680034 7.71296168472859 2.26408328105982 3.40665988272222 0.000758561021727231 -3.58125347629361 7.40769834652148 -0.483450230931083 0.629170832887335 LINC01376 other 1 1 1 3.40665988272222 -0.483450230931083 0.00460263098112641 43.5739459022443 14.5647765434957 2.99173459833844 0.00302751649253754 -8.16600172241061 40.2032314782793 -0.203118043553849 0.839194076041399 CLEC2L other 1 1 1 2.99173459833844 -0.203118043553849 6.08645882821773e-15 207.021947831608 46.3633956424377 4.46520245040282 1.17985224998834e-05 -248.718332316314 73.5014778820053 -3.38385484868197 0.000821603020655868 ZBED5 other 8.0341256532474e-11 1 0.120498310291309 4.46520245040282 -3.38385484868197 0.00153999795131198 9.32955334413317 2.90503751745386 3.21150872857234 0.00148027495183297 3.22507056573229 4.24059360425335 0.76052337637295 0.447605425660568 GUSBP5 other 1 1 1 3.21150872857234 0.76052337637295 0.630883465328472 3.51379670122318 7.36156439610863 0.477316574596644 0.633530130802815 -13.6861204223736 20.6482517240999 -0.662822238184923 0.508020503238507 TRHDE-AS1 other 1 1 1 0.477316574596644 -0.662822238184923 0.0253887999646241 7.32280500573365 2.86272608443662 2.55798312159326 0.0111116832602678 -8.64993269182829 9.70529395593652 -0.89125921699026 0.373636930541727 PPIAL4G other 1 1 1 2.55798312159326 -0.89125921699026 0.543993707054531 0.536825686938714 1.77387891297743 0.302628146155512 0.762405415074379 3.84740192070288 3.5190162211342 1.09331747253579 0.275225328905012 LINC00854 other 1 1 1 0.302628146155512 1.09331747253579 2.22602169209471e-18 96.9743234153824 13.3182116746694 7.28133219265636 3.80147112394355e-12 -150.303808724874 45.6441345829351 -3.29294903054353 0.0011267880667411 VLDLR-AS1 other 3.1751973416039e-14 1 5.2859455978435e-08 7.28133219265636 -3.29294903054353 0.913953671795782 0.00897140378565136 3.25220271390873 0.00275856229603501 0.997801018048284 1.69906640720914 5.00155157580203 0.339707864941229 0.734339666912727 KCNMA1-AS1 other 1 1 1 0.00275856229603501 0.339707864941229 0.000483692474509533 15.7143301057465 4.37427642258569 3.59244103198618 0.000389418960957216 -2.65007282232778 8.12942174406647 -0.32598540286854 0.744688847900699 RNF217-AS1 other 1 1 1 3.59244103198618 -0.32598540286854 0.0992687930583239 2686.72574137737 1269.96732256111 2.11558651443025 0.0352889290420519 1372.32082921069 1995.82867942212 0.687594503155469 0.492294065592823 RPL13AP5 other 1 1 1 2.11558651443025 0.687594503155469 0.00170771195447907 81.5531107992248 26.5467551162503 3.07205571611662 0.00234067830703191 -85.7043560566929 70.0530489542456 -1.22342078376446 0.222225740271689 ZNF853 other 1 1 1 3.07205571611662 -1.22342078376446 1.33666709623121e-21 87.2815042210283 8.22990960192685 10.6054025430113 3.30124853641708e-22 28.3169548793491 25.4902416703907 1.11089393523648 0.267598652792538 PITPNA-AS1 other 1.99136663996525e-17 1 5.10406036215444e-18 10.6054025430113 1.11089393523648 1.43324802451591e-06 13.2258020335121 13.9007419863942 0.951445760698045 0.342232224894389 -71.8039041127982 20.3964315809024 -3.52041502102895 0.000505872838248661 ARHGEF38 other 0.012606849623642 1 1 0.951445760698045 -3.52041502102895 9.15627638151131e-05 3.64615636725811 1.28642213661924 2.83433894945272 0.00493631367003915 -7.0957458948876 3.45322251061066 -2.05481861452154 0.0408516418055532 MKLN1-AS other 0.682142590422593 1 1 2.83433894945272 -2.05481861452154 0.00949129600371258 -14.4859917859527 11.6552239826575 -1.24287545288767 0.214988008617006 49.047465194976 21.7706565575007 2.2529162161661 0.0250644152968129 CTAGE9 other 1 1 1 -1.24287545288767 2.2529162161661 1.3471467926347e-08 12.8022656566756 4.2022182458357 3.04654944310955 0.00254228962601243 -22.8536746009951 6.86453782019015 -3.32923718968775 0.00099113244270781 INTS6-AS1 other 0.000136102240459884 1 1 3.04654944310955 -3.32923718968775 2.87219110641004e-20 63.6572684955775 12.4184172712102 5.12603716764735 5.62234129735635e-07 -77.8958722701926 18.3651079469899 -4.24151453370358 3.04637321386287e-05 ELOA-AS1 other 4.21206825755032e-16 0.462896409846463 0.00633581640799087 5.12603716764735 -4.24151453370358 0.00445394261753985 31.0805865462473 9.71997138712421 3.19760062127538 0.00155204334601961 -24.1830455966195 44.8728505922498 -0.538923765204173 0.59038684306312 BCYRN1 other 1 1 1 3.19760062127538 -0.538923765204173 0.0515539097764067 151.115446122824 65.8254663347715 2.29569883112244 0.0224568702784475 34.6165846790314 104.73880262585 0.330503918425433 0.741274603206424 CBR3-AS1 other 1 1 1 2.29569883112244 0.330503918425433 9.35713545198455e-14 75.221963956893 10.6120674360528 7.08834206059967 1.17710897796536e-11 -56.1769364868539 31.6244357687336 -1.77637751065886 0.0767925987884927 NIFK-AS1 other 1.19406405502775e-09 1 1.61640604854203e-07 7.08834206059967 -1.77637751065886 6.00873315009077e-07 6.87072766435211 3.06528158227093 2.2414670495824 0.0257994951328352 -11.8722672230601 4.23327573258783 -2.80451073188245 0.00540121734183479 EDRF1-AS1 other 0.00544691660055728 1 1 2.2414670495824 -2.80451073188245 1.41010698368108e-08 34.858373722781 7.86814266172039 4.4303179570411 1.37053903086323e-05 -43.4987597950553 17.958447221324 -2.42218936074854 0.0160884864914416 NDUFA6-AS1 other 0.00014223749144391 1 0.139137122413235 4.4303179570411 -2.42218936074854 8.57629010625623e-24 221.83928515018 28.998875243542 7.64992722259402 3.49420819672643e-13 -162.172678423459 54.8150952108305 -2.95854048596848 0.00336292836210703 PRMT5-AS1 other 1.30316728164563e-19 1 4.97575247213844e-09 7.64992722259402 -2.95854048596848 0.881489120501768 0.15025126911114 1.21394088021449 0.123771488018916 0.901590033391179 1.79216321215965 3.57210573208744 0.501710572579372 0.616287687506091 EIF3IP1 other 1 1 1 0.123771488018916 0.501710572579372 0.00120175145163634 42.5956766357748 13.5196870909864 3.15064071743003 0.00181311915377666 7.17297905597556 20.8488682326868 0.344046447793736 0.731080139757143 ZNF503-AS2 other 1 1 1 3.15064071743003 0.344046447793736 6.56718044374718e-05 4.31472988080254 30.0622414781066 0.143526552534176 0.885981402124861 -190.982461938479 52.3550114907022 -3.64783535521515 0.000317325467546302 B3GNT9 other 0.497135559591662 1 1 0.143526552534176 -3.64783535521515 0.215432633600393 27.2278071221675 15.6083573637566 1.74443770651945 0.0822165125708508 16.7105206090553 25.2734227940206 0.66118945365045 0.509052547239646 NR2F1-AS1 other 1 1 1 1.74443770651945 0.66118945365045 8.48290781553886e-14 233.54963375639 33.340015881712 7.00508465817797 1.92489135569868e-11 -14.6072286153027 53.4182876067826 -0.273449960111562 0.784714111906822 CDKN2AIPNL other 1.08403078974771e-09 1 2.6274767005287e-07 7.00508465817797 -0.273449960111562 0.00271053579028365 22.8886454789183 7.04258362506804 3.25003531338219 0.00130019926876123 57.9689547019217 31.947595863876 1.81450131486948 0.0707103027002332 LINC00987 other 1 1 1 3.25003531338219 1.81450131486948 0.00198663397111373 180.500072856396 91.474774570928 1.97322238511164 0.0494899719242066 -269.893212698086 165.022656984919 -1.63549186293099 0.103111184077029 CKMT1B other 1 1 1 1.97322238511164 -1.63549186293099 4.06486021390487e-07 41.9256489919154 13.9039905819019 3.01536805170797 0.00281016195166419 -67.7603991440181 26.6229365810984 -2.5451887674978 0.0114765295536551 SMG1P1 other 0.00374007788281387 1 1 3.01536805170797 -2.5451887674978 0.0160523658959838 -6.24412485768992 6.06359915353694 -1.02977203795665 0.304070363116912 -26.8921564505278 9.53275938644942 -2.82102540936408 0.00515483275147528 RNF223 other 1 1 1 -1.02977203795665 -2.82102540936408 1.42070513743981e-12 66.0966287930333 18.7803163088464 3.51946302213764 0.000510037469193422 -114.992650515222 32.0449567962148 -3.58847887505358 0.000397133712142821 PITRM1-AS1 other 1.74107414593249e-08 1 1 3.51946302213764 -3.58847887505358 0.411776529907253 -18.9371771350537 29.3371124109409 -0.645502422658044 0.519143799852488 -59.7636503154479 44.8581392945643 -1.33228108109892 0.18387888578268 PRSS56 other 1 1 1 -0.645502422658044 -1.33228108109892 0.0388836954461726 7.65428754872572 8.60439587167919 0.889578729625784 0.374486976919313 -23.282110546275 14.8727898174778 -1.56541649764424 0.118660883522167 FOXD2-AS1 other 1 1 1 0.889578729625784 -1.56541649764424 0.645250723059946 11.0493010209232 11.8690483959593 0.930934027085508 0.352757955761156 15.079503627469 34.3640846984502 0.438815808999243 0.661162253562522 CECR7 other 1 1 1 0.930934027085508 0.438815808999243 0.135216496576488 16.9826188239645 10.304110693921 1.64814017710267 0.100495718190331 -6.40259368265584 23.1817381771365 -0.276191268908841 0.782614026454995 ZNF737 other 1 1 1 1.64814017710267 -0.276191268908841 5.58172614074094e-11 468.117830341863 86.5613311831159 5.40793243291955 1.40062090377464e-07 -287.109521510803 159.638621780533 -1.79849661885401 0.0732110701341314 RGL2 other 6.42345044276467e-07 1 0.00164236807176614 5.40793243291955 -1.79849661885401 8.44252558321148e-13 7.54618354327643 1.04598904733189 7.21440015316152 6.68261879310348e-12 -4.99725400439 4.45552848094274 -1.12158502089356 0.263132531333915 LINC01637 other 1.04349616208494e-08 1 9.23003307703453e-08 7.21440015316152 -1.12158502089356 0.00384443330484028 -5.98407098887059 4.73577208491088 -1.26358931164298 0.207459393589493 -23.9769721018086 7.43482117940869 -3.22495612513381 0.00141376945655184 UNC5B-AS1 other 1 1 1 -1.26358931164298 -3.22495612513381 0.349410257571847 33.1138888888887 38.1676076583071 0.867591419020509 0.386391333360097 -45.2171648091863 77.2863798542236 -0.585059940632156 0.558997842030659 SHISA9 other 1 1 1 0.867591419020509 -0.585059940632156 0.000138951645147845 18.7794235184083 5.09087792197686 3.68883791876823 0.000274529186413755 -19.5542527562849 18.9669966676543 -1.03096199672097 0.303520403470019 DGCR5 other 1 1 1 3.68883791876823 -1.03096199672097 0.00242198477627504 7.84072286451894 8.16831037631036 0.959895315346796 0.337969884347262 -25.9773964530251 12.4560272658906 -2.08552822649653 0.0379639145514963 LINC00857 other 1 1 1 0.959895315346796 -2.08552822649653 0.58095312750918 8.71170018281531 11.4870860270492 0.758390784425348 0.448917429342517 -8.62550911951028 26.7861846547993 -0.322013352430348 0.747706402570488 PYY2 other 1 1 1 0.758390784425348 -0.322013352430348 7.99491604127687e-12 406.657975049591 62.7440352847026 6.48122125401038 4.25710255520658e-10 -62.8126543140398 115.595848317444 -0.543381576659628 0.587312149252053 KIFC1 other 9.5147495807236e-08 1 5.57339866527645e-06 6.48122125401038 -0.543381576659628 0.0284351006802772 23.84932206825 9.93452182790743 2.40065123227713 0.017071871915417 -72.9213250499818 62.8590194053117 -1.16007735627864 0.247085560638964 C2orf74 other 1 1 1 2.40065123227713 -1.16007735627864 0.00729044993825505 41.2447140945359 14.6652053217527 2.81241981885915 0.00527386026294755 2.80113084531148 23.496994076707 0.119212305887599 0.905194833203335 P4HA2-AS1 other 1 1 1 2.81241981885915 0.119212305887599 0.000152277611425585 3.90563549443049 0.92235458947377 4.23441867043646 3.14501004400437e-05 2.77285098623677 3.97396290143991 0.697754623031852 0.485931093784428 DCTN1-AS1 other 1 1 0.30972058913355 4.23441867043646 0.697754623031852 0.848100844902009 -4.71414868105524 16.7827004013834 -0.280893334702361 0.779008137847254 -13.4973321342926 23.726043202067 -0.568882557421826 0.569910493561283 AMY1A other 1 1 1 -0.280893334702361 -0.568882557421826 1.61867823139926e-11 99.5453843575939 27.6903513474182 3.59494840309692 0.000385859094137541 -99.5623655777139 40.5646793368517 -2.45441027034731 0.0147455041649922 FAM200B other 1.90599361747263e-07 1 1 3.59494840309692 -2.45441027034731 0.00269333746902462 25.9327443501334 7.5381352467557 3.44020682851166 0.000672915226229086 -10.9949321886786 33.0776819466605 -0.332397300584983 0.739846239589686 DGUOK-AS1 other 1 1 1 3.44020682851166 -0.332397300584983 0.000955094786902294 3.24653208316266 2.8821304343439 1.12643482212897 0.260996706263488 -11.8435706764442 4.64714500896586 -2.5485692083191 0.0113790081075214 LINC01238 other 1 1 1 1.12643482212897 -2.5485692083191 1.64204705299892e-14 96.3896763256227 23.7399390082211 4.06023268603357 6.43369973085059e-05 -149.802011717196 33.9887389058057 -4.40740129053767 1.51289197984076e-05 LINC00649 other 2.14073674299469e-10 0.231850695910596 0.615512053250476 4.06023268603357 -4.40740129053767 0.19978685695588 9.12045889101337 5.36335135542769 1.70051489947298 0.0901898416990324 15.3201675316399 20.4018899611334 0.750919035482768 0.453357764171335 FLG-AS1 other 1 1 1 1.70051489947298 0.750919035482768 0.324205966052387 22.5295313171747 17.2261921642027 1.30786485500799 0.192061170308549 2.57150478342041 48.7503883893879 0.0527483958257076 0.957972421531318 PTENP1 other 1 1 1 1.30786485500799 0.0527483958257076 0.152694514412766 -0.234267397904532 11.536174934284 -0.0203071988106144 0.983813256536035 -27.8101324591455 16.7399288181846 -1.6613052995145 0.0978085257564862 LINC01679 other 1 1 1 -0.0203071988106144 -1.6613052995145 0.440716963725825 -2.48404578905966 2.03445555855369 -1.22098798305803 0.223163659013831 -0.43046879513098 4.72187704229671 -0.0911647616562249 0.927429776056099 ZEB2-AS1 other 1 1 1 -1.22098798305803 -0.0911647616562249 1.76601025592699e-05 42.1334566360638 13.3632947120637 3.15292430077351 0.00180163042893387 -68.0002845048992 28.9829542027586 -2.34621647017704 0.01969947004969 LRRC37A2 other 0.141687002833023 1 1 3.15292430077351 -2.34621647017704 0.796244554239994 -1.63546140140923 6.17606476745659 -0.264806387722313 0.791359911167835 -7.61129232982269 11.4307551097815 -0.665860851424382 0.506066417531156 ABCA17P other 1 1 1 -0.264806387722313 -0.665860851424382 0.0062401312843591 48.5671335212685 22.4174868726638 2.16648430741324 0.0311426351683161 -75.6500742577947 46.2616804017542 -1.6352642965154 0.103150329670791 GOLGA2P5 other 1 1 1 2.16648430741324 -1.6352642965154 0.118444482159064 6.75417585326807 4.60452819895266 1.46685513942652 0.143805597488157 -4.44847712691367 9.07072820177458 -0.49042116883663 0.624311694730315 LINC01410 other 1 1 1 1.46685513942652 -0.49042116883663 0.578150902877373 -3.45523151178013 3.29952535605151 -1.04719047103034 0.295951743002817 -3.07074645676537 5.2261701366885 -0.587571084838641 0.557313111126633 LINC00426 other 1 1 1 -1.04719047103034 -0.587571084838641 0.000197878384142343 20.0152291460849 4.84058273496316 4.13488008406847 4.74536595300991e-05 9.30442304356683 14.6374469918236 0.635658871985275 0.525537182633416 MAP3K20-AS1 other 1 1 0.459019248634649 4.13488008406847 0.635658871985275 4.01863287373141e-09 5.15474948283268 4.60230252301543 1.12003708079913 0.263682349363579 -26.8491992037574 6.76823759016507 -3.96694100141697 9.30906165424128e-05 CD81-AS1 other 4.18902290757762e-05 1 1 1.12003708079913 -3.96694100141697 0.00290855989752307 7.82338081538135 5.89216630740292 1.32775967398477 0.185383110406641 -17.7509710360883 8.43565302627926 -2.10427941746648 0.0362820717810625 PAXBP1-AS1 other 1 1 1 1.32775967398477 -2.10427941746648 3.61737658073466e-19 374.129473900537 47.6427808515456 7.85280513046291 9.34613353192284e-14 -245.905298652054 89.0352079702843 -2.76188829405695 0.00613687052641028 TMEM250 other 5.22566220852928e-15 1 1.34182439117816e-09 7.85280513046291 -2.76188829405695 0.572637548485034 -1.5177008529665 4.32097147344369 -0.351240655554927 0.725680726744325 -7.54539116659364 7.43864540370478 -1.0143501615006 0.311320453018315 LINC00707 other 1 1 1 -0.351240655554927 -1.0143501615006 9.46842651400461e-10 11.3321280862448 1.7064144568193 6.64090018750047 1.69848223057522e-10 2.50718952035019 8.19750135744131 0.305848015270444 0.759955181863309 SCARNA12 other 1.0240103274896e-05 1 2.25541455398083e-06 6.64090018750047 0.305848015270444 0.0175579602137974 3.78645481443515 1.32897358248145 2.84915732287554 0.00471731201538553 2.0731824041501 3.86866949181834 0.535890286966765 0.592470709438334 SNORD10 other 1 1 1 2.84915732287554 0.535890286966765 0.00030276488273912 901.341774360098 324.564979076917 2.77707649458537 0.00586920168299671 -980.468817440287 584.526510221593 -1.67737271157914 0.0946268403903816 TXNDC5 other 1 1 1 2.77707649458537 -1.67737271157914 0.000106426003389061 26.9275290598642 14.021226319221 1.92048316222887 0.0558423662175675 -110.993331016212 37.1317428351182 -2.98917644423729 0.00305311778270364 CASTOR1 other 0.786062461031603 1 1 1.92048316222887 -2.98917644423729 0.00416534980440083 86.9306109664018 26.7506083592723 3.24966856076266 0.00130351658534721 -38.2349907129592 110.637686222956 -0.345587403517355 0.729924936997803 RNF103 other 1 1 1 3.24966856076266 -0.345587403517355 0.0541328371474993 98.1659884357759 41.7811345398899 2.34952902827599 0.0195098161744928 10.6075715129749 112.846131476731 0.0940003115229715 0.925177861388035 RBM14 essential 1 1 1 2.34952902827599 0.0940003115229715 3.15152318986339e-16 93.578637857839 10.914189354694 8.57403466411295 8.21681231416411e-16 -32.3374134826636 43.1773774382057 -0.748943437543051 0.454550579024097 ALKBH6 other 4.29930793561163e-12 1 1.2135410106789e-11 8.57403466411295 -0.748943437543051 2.15810030878634e-06 14.2322399490896 3.20247201739633 4.44414186034347 1.28412032738793e-05 -9.18199377016581 7.62977106649582 -1.20344289365197 0.229847500862125 ASB14 other 0.0186999391756336 1 0.130697766921543 4.44414186034347 -1.20344289365197 1.14787484283976e-06 168.38242236935 34.9452881572 4.8184585461676 2.41595274780622e-06 15.7987211424464 63.9050854563843 0.247221657394216 0.804924566589214 PCDHA13 other 0.010179354106303 1 0.0260488025268466 4.8184585461676 0.247221657394216 0.000674971538649963 44.5003667392531 12.4867024864788 3.56382053528064 0.000431524110124905 -37.1281048760072 55.0566837029575 -0.674361446764959 0.500654277884408 GATS other 1 1 1 3.56382053528064 -0.674361446764959 0.0484972762766903 4.34700232998784 3.2834655373003 1.32390679317499 0.186649620357482 -23.2057018358606 12.8358926480313 -1.8078759671942 0.0717344195135463 MYLK-AS1 other 1 1 1 1.32390679317499 -1.8078759671942 0.0157391463814196 -1.29333086404512 1.84268761785971 -0.70187201102883 0.483361325822799 -11.1506403001557 3.8911705010348 -2.86562624207558 0.00448806126299898 PSMD6-AS2 other 1 1 1 -0.70187201102883 -2.86562624207558 2.84919916480514e-09 958.597018280078 156.556908938434 6.12299402677303 3.21258802373812e-09 -51.878442056279 342.208560338717 -0.15159890215759 0.879616091762185 NME1 other 3.00134640020574e-05 1 4.07388287290231e-05 6.12299402677303 -0.15159890215759 0.190093804398016 -54.3486708757541 40.0166471410298 -1.35815153838887 0.175536943485793 -181.97249823327 116.489284663055 -1.56213937410316 0.119413598320604 TNFSF12 other 1 1 1 -1.35815153838887 -1.56213937410316 3.66994518121831e-05 60.3065980242576 22.4046192044144 2.69170377206747 0.00754946511696516 -135.136012236616 57.7103198815571 -2.34162646323854 0.0199219018597353 CDRT4 other 0.284917848535394 1 1 2.69170377206747 -2.34162646323854 0.568074748925045 22.8306693306694 39.2408077344782 0.581809362466555 0.561175212031028 101.677498427499 98.6864682347485 1.03030841255394 0.303777178544258 APOBEC3G other 1 1 1 0.581809362466555 1.03030841255394 2.05887897936854e-05 2.5072337889425 0.625214480596147 4.01019788689448 7.88726465910042e-05 -8.00614512664781 3.83860357014652 -2.08569209618648 0.0379595885391771 HLTF-AS1 other 0.164072065865879 1 0.748107052915674 4.01019788689448 -2.08569209618648 0.0255904580295499 -15.376664937494 7.51226512404555 -2.0468746354912 0.0416348901913956 -42.2337086368519 17.7564151433406 -2.37850423612625 0.0180763045695218 TLR9 other 1 1 1 -2.0468746354912 -2.37850423612625 1.15116312558576e-10 335.893594402044 47.9854225830562 6.99990906239615 2.04105148864642e-11 -123.192672289708 206.060803814096 -0.597846218249494 0.550445519708931 WBP1 other 1.30553410072681e-06 1 2.78358602021598e-07 6.99990906239615 -0.597846218249494 2.40368752924384e-20 210.50161193331 20.3629082781815 10.3375023379573 6.06383993488522e-21 29.1168691770987 63.5418172563307 0.458231609266696 0.64720241969269 MRPS17 other 3.52933439918874e-16 1 9.32133474790556e-17 10.3375023379573 0.458231609266696 8.26429378877065e-08 270.783520512504 56.9524045557968 4.75455817229307 3.2562219652568e-06 -314.480313506466 136.130627886367 -2.31013636232526 0.0216434095626891 GET4 other 0.000795520920107063 1 0.0347536570351859 4.75455817229307 -2.31013636232526 2.34133958119379e-05 186.413122724498 39.8087598872535 4.68271614721127 4.46675574147737e-06 -29.8696275525203 137.541750543624 -0.217167714053826 0.828239855109721 C1orf226 other 0.185527748413796 1 0.0471644738742595 4.68271614721127 -0.217167714053826 1.65945801255108e-14 546.073159377884 71.8639801090676 7.59870464381615 4.98042301876676e-13 -170.730388448781 179.279731867511 -0.952312827949521 0.34179325155672 ADSL essential 2.16326946516159e-10 1 7.06522809442252e-09 7.59870464381615 -0.952312827949521 4.94411171352496e-05 30.0415689737352 6.69122394069636 4.48969713762244 1.05312968265044e-05 17.6663241100185 17.1054845461218 1.03278711938177 0.302617580285711 LILRA4 other 0.378718957256012 1 0.10797738636215 4.48969713762244 1.03278711938177 0.515551512720791 -10.9727291949682 12.2605757542719 -0.894960352179625 0.371596656157727 -30.9943348752515 30.5665127380653 -1.01399643265989 0.311482280388334 LILRA2 other 1 1 1 -0.894960352179625 -1.01399643265989 4.48108348553256e-14 38.8644605311333 5.15662814152375 7.53679719857579 8.09036811142352e-13 197.86350580166 55.2801938227646 3.5792838649596 0.000411226880658803 LINC00888 other 5.77522039615436e-10 1 1.1417936515652e-08 7.53679719857579 3.5792838649596 0.852644280909609 12.9652544630962 26.5392340790576 0.488531599083609 0.625571365257908 2.57215893951509 37.5190523127963 0.0685560743398048 0.945393915614535 AMY2B other 1 1 1 0.488531599083609 0.0685560743398048 5.35844558748892e-29 442.956653715395 41.0951379194483 10.7788092738281 8.36704562582161e-23 -166.153156872268 78.8058613339992 -2.10838577308442 0.0359088211273323 LY6G5B other 8.36292602839395e-25 1 1.29689207200235e-18 10.7788092738281 -2.10838577308442 0.00374520548725525 395.734303976194 118.527567820393 3.33875326435331 0.000958649752651032 402.180038056488 232.841723970606 1.72726791057113 0.0852505924326899 PSMB9 other 1 1 1 3.33875326435331 1.72726791057113 0.00755475352186287 3.49786271486234 1.12647778189613 3.10513245008226 0.00210359190820641 -3.09694317202594 7.39047266849562 -0.419045345398232 0.675514939005834 ERICH6-AS1 other 1 1 1 3.10513245008226 -0.419045345398232 0.00180973136145303 343.362610460954 220.792017872565 1.55514050629826 0.121079638668345 -821.838643420106 372.862240889694 -2.20413480715854 0.0283556257460382 PCDHGC3 other 1 1 1 1.55514050629826 -2.20413480715854 5.92381905874343e-05 21.6174146110299 5.14593506107443 4.20087201926648 3.61186253774429e-05 1.489159180429 13.9112806423845 0.107046879342789 0.914830992109698 SMKR1 other 0.450506439417438 1 0.353745816946676 4.20087201926648 0.107046879342789 0.0378086982552162 1571.56554953178 612.460025546631 2.56598877311076 0.0108262547413108 1467.56323311976 938.7248854722 1.56335818495058 0.119135335734224 UGT1A5 other 1 1 1 2.56598877311076 1.56335818495058 0.358533293693808 15.8789480626096 20.2403847632834 0.784518093322734 0.433416377208549 -35.9858393918237 46.1713269081795 -0.779397990085674 0.436420426460131 ZNF542P other 1 1 1 0.784518093322734 -0.779397990085674 1.5235839446997e-07 138.750678398375 29.8882234789504 4.64231935685618 5.40823211877452e-06 -163.582543952231 71.440401161841 -2.28977639111588 0.0228146528444584 COX19 other 0.00144131041168591 1 0.0567756207828949 4.64231935685618 -2.28977639111588 9.53371591392459e-05 20.3344200689173 4.6475228835618 4.37532435630166 1.73175280566986e-05 11.4860391555579 17.6742194771701 0.649875326624436 0.516323241870709 B4GALT4-AS1 other 0.708259755245458 1 0.174352872474842 4.37532435630166 0.649875326624436 0.644024853881153 -2.99113246247678 7.36889498924291 -0.405913297291281 0.685126619924132 -14.9950143527189 16.3287219428367 -0.918321372928825 0.359267231701515 TCAM1P other 1 1 1 -0.405913297291281 -0.918321372928825 0.00171779859801442 3.52818991097925 1.17169934961998 3.01117339710359 0.00284705898763495 -3.18062908011871 3.36014283999363 -0.946575556926247 0.344695253563708 GHRLOS other 1 1 1 3.01117339710359 -0.946575556926247 4.30747643643394e-05 90.761079455524 21.8897598528181 4.14628027286646 4.5147743202185e-05 -127.564205151654 107.507667228647 -1.18655913982721 0.2364331213297 ACAD11 other 0.332106433249056 1 0.438113700034004 4.14628027286646 -1.18655913982721 7.27848090178443e-07 76.6770786402083 16.3937017877195 4.67722785451952 4.63878321653784e-06 -50.4629061472263 37.5178120448164 -1.34503862024114 0.17976270196762 PPIL3 other 0.0065499049635158 1 0.0489159690183915 4.67722785451952 -1.34503862024114 5.25664218456186e-05 13.7817395367296 3.14510462479089 4.38196536550701 1.68106405806241e-05 -3.70879113146448 14.8735658301956 -0.249354537694994 0.803274745809649 RPL13P5 other 0.401765162166063 1 0.169400825130949 4.38196536550701 -0.249354537694994 1.37318931797727e-12 26.174188140497 3.90367486595149 6.70501233819259 1.64496004487358e-10 -25.5915204283048 11.6805362473847 -2.19095424099513 0.0294955717169927 CDKN2B-AS1 other 1.68339278490834e-08 1 2.18549391561904e-06 6.70501233819259 -2.19095424099513 0.0562235914740946 -10.2263793210586 4.27870717958087 -2.39006290728695 0.0175238966571345 -7.50839175189197 11.1244106567305 -0.674947373265945 0.500280415426376 TNFRSF13B other 1 1 1 -2.39006290728695 -0.674947373265945 1.2365713840226e-05 11.3246251443881 2.34040919089602 4.83873725519447 2.20796854990773e-06 1.10308230692391 14.8209498901878 0.0744272340907249 0.940725961732063 TM4SF1-AS1 other 0.100483790665676 1 0.0238681400245025 4.83873725519447 0.0744272340907249 0.11076108212841 1.0171776380021 1.6128173940956 0.630683697810993 0.528774964851524 10.5672270702756 5.02056362812203 2.10478899442378 0.0362236446226464 L1TD1 other 1 1 1 0.630683697810993 2.10478899442378 0.0162460420719105 186.955554687255 64.6039603048779 2.89387142529619 0.00413841121361861 53.2017770622982 411.538695347299 0.129275272687058 0.897242957259916 LINC02067 other 1 1 1 2.89387142529619 0.129275272687058 0.741975684887127 -607.493323095551 834.588032585094 -0.727896038976107 0.467301060284697 -1094.08518293208 2287.54510354522 -0.478279174140205 0.632834295923908 AQP1 other 1 1 1 -0.727896038976107 -0.478279174140205 0.254771663895498 10.2064879546303 6.32209312934784 1.61441594513227 0.107622789731011 -11.5611577071558 41.1291310226716 -0.281094139839302 0.778856721188045 AADACP1 other 1 1 1 1.61441594513227 -0.281094139839302 5.07187792117802e-22 277.024754114541 27.3566553995795 10.1264116562582 1.22175460930082e-20 -223.788436617431 104.435943218671 -2.14282965921853 0.0330208118987622 ISY1 other 7.59310843579561e-18 1 1.87624855350327e-16 10.1264116562582 -2.14282965921853 0.387598688844413 2.02603546111445 29.3347749974813 0.0690659962889917 0.944987833792409 -51.6686342285043 49.858741059277 -1.03630041855801 0.300982421146115 PNMA2 other 1 1 1 0.0690659962889917 -1.03630041855801 2.08081666295738e-76 979.319153288776 36.7499062279139 26.6482082216831 1.94822594404751e-77 205.007281705398 337.159952896968 0.608041613317124 0.54367288997295 LRRD1 other 3.32181572074516e-72 1 3.11053754226625e-73 26.6482082216831 0.608041613317124 0.888487629916996 2.97938931297703 13.9667761903249 0.213319757714806 0.831237364937162 17.73213740458 36.712251772681 0.483003263171537 0.629481949085541 KRBOX1 other 1 1 1 0.213319757714806 0.483003263171537 0.000973282911841801 226.060233061208 187.170101333814 1.20777961570921 0.228185020362894 -819.967576672992 305.350679424915 -2.685330775151 0.00769274804353425 PCDHGC5 other 1 1 1 1.20777961570921 -2.685330775151 4.00437142258981e-05 83.5669263616956 28.4771409989452 2.93452655113064 0.00362454752087836 -178.858887362014 76.266884653635 -2.34517101589109 0.0197346777004709 ARHGEF25 other 0.309577954680418 1 1 2.93452655113064 -2.34517101589109 0.000635641991118407 322.626429241572 117.035504790115 2.75665431460439 0.00623764252109933 -755.759426102029 389.52829238062 -1.94019135678995 0.0533975262822883 TMEM189 other 1 1 1 2.75665431460439 -1.94019135678995 2.27116312679626e-11 75.8334088499345 11.4092684424566 6.64664954045082 1.67095299240387e-10 -60.2079377781394 37.3292006010678 -1.61289116318278 0.107945037422785 RDH14 other 2.65589816047555e-07 1 2.21919266921157e-06 6.64664954045082 -1.61289116318278 0.408629959342809 -2.18171950048031 2.73495188030695 -0.79771769155787 0.425756728919751 19.1025437079731 18.572538897424 1.0285370144317 0.30464588323323 LINC00886 other 1 1 1 -0.79771769155787 1.0285370144317 1.67045016323387e-15 72.4939908958292 10.2044928404218 7.10412482320215 1.05395689529736e-11 -60.5607501274232 28.1675167865951 -2.15002091189821 0.0324320135841209 NDUFB2-AS1 other 2.23740094863544e-11 1 1.44908533534435e-07 7.10412482320215 -2.15002091189821 0.0128432794335946 48.7080167467823 19.6416453547747 2.47983383606618 0.0137546743401429 -78.1362942376279 73.0619337556819 -1.0694528630862 0.285820807417714 PLCXD2 other 1 1 1 2.47983383606618 -1.0694528630862 5.74463158911916e-12 4149.44824202072 624.927887981071 6.63988329185656 1.70858944322009e-10 -1845.7662258755 1757.92588630566 -1.04996817002021 0.294668164823245 MIF other 6.87057938058652e-08 1 2.26849420376332e-06 6.63988329185656 -1.04996817002021 0.00032487629987858 32.6497859844534 8.02616902086213 4.06791657384588 6.22505414605217e-05 28.9194102105373 22.1836207598441 1.30363796440688 0.193463394158374 HOXA11-AS other 1 1 0.596484688274718 4.06791657384588 1.30363796440688 7.23581287151673e-07 41.4627450547896 10.0424189911943 4.12876071902062 4.86070365049417e-05 -43.6512087122127 24.8651712661612 -1.75551610905722 0.080300870182504 TPM3P9 other 0.00651627491505201 1 0.469592579674241 4.12876071902062 -1.75551610905722 2.53250019699557e-15 52.6903713056713 11.8139789669837 4.46000212569568 1.20188471688333e-05 -73.6978954162761 20.0073236517565 -3.68354592043628 0.000277649728055779 NSUN6 other 3.37632926263449e-11 1 0.122652335357943 4.46000212569568 -3.68354592043628 0.142165680488168 -29.6847708260585 16.2743309456806 -1.82402403669548 0.0692415837757831 1.06356546778608 31.9701428413897 0.033267460613568 0.973485611622644 HLA-DOB other 1 1 1 -1.82402403669548 0.033267460613568 0.0901026059474939 11.1048830174702 18.0903109282313 0.613858051502041 0.539824067471209 -65.0023046690125 38.2009861879044 -1.70158708336159 0.0899797085390003 PRICKLE2-AS1 other 1 1 1 0.613858051502041 -1.70158708336159 0.0374716499809974 1585.87809265648 617.19962742693 2.56947350935371 0.0107205912604922 1481.5350364164 945.989330573407 1.56612235311193 0.118486891771959 UGT1A9 other 1 1 1 2.56947350935371 1.56612235311193 2.02877802416896e-10 35.3716869889221 8.6276954309507 4.09978391935706 5.45971258197176e-05 -87.9537911349822 22.2750859402266 -3.94852757789574 0.000100126541510556 YAE1D1 essential 2.27466592069823e-06 1 0.525551933140601 4.09978391935706 -3.94852757789574 0.574312124943039 0.157211350494882 6.8154568743295 0.0230668836137781 0.981613896859463 -13.8028136167528 14.3920784420688 -0.959056308115058 0.338385228083263 ADAMTS9-AS1 other 1 1 1 0.0230668836137781 -0.959056308115058 3.69757046947501e-12 194.619520449772 31.9922261437486 6.08333785761892 4.28622421364173e-09 -237.323598411056 95.2990500725158 -2.49030392465055 0.0134007264438598 CRCP other 4.45963974323381e-08 1 5.40492873340222e-05 6.08333785761892 -2.49030392465055 3.48134887150685e-05 16.1333628868081 3.72013587056645 4.33676710962481 2.04639053767048e-05 -27.2326876619906 23.5738179502681 -1.1552090424827 0.249029932461605 WWTR1-AS1 other 0.270848942203233 1 0.204659517672425 4.33676710962481 -1.1552090424827 0.00167530622609706 13.9929025043603 3.9066159874454 3.58184744784973 0.000404062275336393 9.61874981508049 10.1397490786649 0.948618130533364 0.343656915147557 CDRT1 other 1 1 1 3.58184744784973 0.948618130533364 0.000456936824339902 76.6409240523242 23.0917386900816 3.3189758935408 0.00102726337421614 -53.5074174389368 56.0079936198686 -0.955353226935723 0.340250516913756 PDXP other 1 1 1 3.3189758935408 -0.955353226935723 6.04407188701991e-19 222.300841403638 24.7394630153759 8.98567771117244 4.35990383536555e-17 -41.8431861488512 48.054752854887 -0.870739805388383 0.384661260583815 RPP21 essential 8.70648555325218e-15 1 6.53069995499406e-13 8.98567771117244 -0.870739805388383 0.876040159000368 48.8744213417022 96.4318695702896 0.506828515920014 0.612685761610925 67.1084281417548 252.363536717493 0.265919668961047 0.790502527113517 CD302 other 1 1 1 0.506828515920014 0.265919668961047 1.06091979068034e-07 73.6039109004342 14.1787717435877 5.19113448128689 4.10623619346872e-07 -7.19888388120188 27.0795604240008 -0.265841977066269 0.790563043760741 EGFL8 other 0.00101476977978575 1 0.00467618177712218 5.19113448128689 -0.265841977066269 1.36639555882721e-09 674.117218325386 102.361770324592 6.5856346191331 2.38201973860735e-10 179.715333591611 471.169362252513 0.381424065292464 0.703190826061871 ATP5J2 essential 1.46573251595395e-05 1 3.14450425693556e-06 6.5856346191331 0.381424065292464 7.76970910562009e-05 26.7557873942837 8.6565013986566 3.09083152212462 0.00220390610430957 -30.8965368232608 18.2797792518642 -1.69020295035072 0.0921390116832679 PTPRG-AS1 other 0.5832720625589 1 1 3.09083152212462 -1.69020295035072 5.26372026773933e-09 135.918403270388 23.6405110151198 5.74938516275976 2.39353021376614e-08 -17.3556312653971 53.1267078750035 -0.326683733278399 0.744157422748401 ARHGAP8 other 5.45374056940472e-05 1 0.000291651656547404 5.74938516275976 -0.326683733278399 2.86038109603967e-05 8.35541139592336 2.03220010169991 4.1115101750729 5.22067734732278e-05 -1.52714019055738 3.54777216202822 -0.430450468861093 0.667211383990489 GUSBP2 other 0.224539916039114 1 0.503377709828862 4.1115101750729 -0.430450468861093 9.04941680278752e-25 1281.16904354172 123.175694653706 10.4011513565528 1.4979274216382e-21 -643.443260295901 342.265062061381 -1.87995600959267 0.0611827929543238 ARPC4 essential 1.38338434664213e-20 1 2.30935470593961e-17 10.4011513565528 -1.87995600959267 3.07300141925038e-09 9.00029908936086 1.89705659850752 4.7443492705709 3.38233483565391e-06 -3.58416374614704 3.03923805860092 -1.17929680960792 0.23931049329308 CORT other 3.2291098913483e-05 1 0.036060811577417 4.7443492705709 -1.17929680960792 1.99424993483915e-08 10.8730166316192 1.76816546050351 6.14932079293246 2.80204388651582e-09 4.4791236813251 9.74467195633503 0.459648482924375 0.646139811969516 PAQR9-AS1 other 0.000199444935983264 1 3.55999675781834e-05 6.14932079293246 0.459648482924375 0.0255440541480004 1867.05953671759 688.92719410739 2.71009702140826 0.00715542510790583 1809.33592902908 1055.92703917279 1.71350468536776 0.0877632883058947 UGT1A1 other 1 1 1 2.71009702140826 1.71350468536776 0.825725482221592 44.4408521257265 159.97744569838 0.277794484914549 0.781380384831477 -191.224260995615 438.486544614678 -0.43610063602671 0.663108372216698 INMT other 1 1 1 0.277794484914549 -0.43610063602671 1.1591731402673e-25 1297.22546924049 115.136593679982 11.2668390455087 2.3985695728354e-24 -963.963868102161 516.367414870259 -1.86681777420902 0.0630229946191893 ARPC1A other 1.78327195898722e-21 1 3.74008953492223e-20 11.2668390455087 -1.86681777420902 0.00161280071729442 79.3566937586258 21.9463106635627 3.61594688853017 0.000357224166059619 55.8414936960827 42.4196913151563 1.31640499882966 0.189158678261197 TMEFF1 other 1 1 1 3.61594688853017 1.31640499882966 0.0141917267939703 -0.597131693534684 3.16891061229589 -0.188434375907517 0.850679294689332 20.3468791073201 7.9660447423009 2.5542009573804 0.011198900682025 FABP5P3 other 1 1 1 -0.188434375907517 2.5542009573804 0.117904552152028 4.60757927467596 2.25954779092558 2.03915991207628 0.0424077946449071 6.54161905514793 6.72856076621143 0.972216686813285 0.331812925063838 RPSAP52 other 1 1 1 2.03915991207628 0.972216686813285 0.863905683010262 398.5598919331 737.16993658926 0.54066216234639 0.589182921861561 35.0918162446128 2535.03579336005 0.0138427300855191 0.98896559996259 SPRR2A other 1 1 1 0.54066216234639 0.0138427300855191 2.04410381789535e-10 893.547965398516 169.337718495446 5.27672141409267 2.71657741340062e-07 -321.817715826023 242.152053085519 -1.3289902428057 0.184981519403049 ATP5O other 2.2912359694789e-06 1 0.0031311012138971 5.27672141409267 -1.3289902428057 0.336689662923728 -91.3834449603732 74.2858246544068 -1.23015993139348 0.219704006986354 -181.86878251568 146.581868936053 -1.24073177559921 0.215777883434738 PLEKHO2 other 1 1 1 -1.23015993139348 -1.24073177559921 2.40634652383583e-10 35.6523281438468 14.9573472691531 2.38359967862573 0.0178357468237516 -94.342943807987 24.9425307516796 -3.78241264879002 0.000191285649166728 C8orf58 other 2.68807698716652e-06 1 1 2.38359967862573 -3.78241264879002 0.102659036714394 -8.13479294059474 8.07513301701646 -1.00738810412814 0.314640347160585 -27.5537888320045 12.862429079531 -2.14219170124351 0.033062743553674 HOGA1 other 1 1 1 -1.00738810412814 -2.14219170124351 5.56347294483392e-29 535.500272030161 44.9481765295384 11.9137262816045 3.87960365264882e-26 -377.976113957391 191.462693806063 -1.97415019314547 0.0494833803765904 PI4KA essential 8.68179953041334e-25 1 6.07662320114384e-22 11.9137262816045 -1.97415019314547 0.611781038626556 34.9752934768755 289.584098621474 0.120777672680823 0.903956304901171 -461.557543485566 560.762534610363 -0.823089124180295 0.411178350772512 AKAP2 other 1 1 1 0.120777672680823 -0.823089124180295 2.41978689608953e-10 221.695558205133 56.5413998199175 3.92094215762655 0.000111805726797825 -314.377056357847 101.576459599473 -3.09497946273645 0.0021743655279177 HYPK essential 2.70241800555278e-06 1 1 3.92094215762655 -3.09497946273645 0.00816819617077695 336.644960124964 109.187256846708 3.08318909959971 0.00226091812821185 722.7161780741 842.852480098521 0.85746461585973 0.391951450256051 SDHAP2 other 1 1 1 3.08318909959971 0.85746461585973 0.00114024834772539 79.3486666467275 26.2338706925249 3.02466485318681 0.0027307153160933 -269.193017954463 169.900051186027 -1.58441987554035 0.114277464152454 AMACR other 1 1 1 3.02466485318681 -1.58441987554035 1.00391499701973e-14 204.098302339267 25.071452614636 8.14066522097408 1.40755392843454e-14 7.69528582245574 79.5321630888156 0.096756903416071 0.922990441853468 MTFP1 other 1.31693569309048e-10 1 2.04644265655098e-10 8.14066522097408 0.096756903416071 1.68869929616698e-07 320.295025118926 72.8332032892094 4.397651217496 1.5715876217781e-05 -68.7238874316457 105.717283582924 -0.650072392162242 0.516194118536783 SNHG3 other 0.00159295004607431 1 0.158808929180677 4.397651217496 -0.650072392162242 0.356671063754914 -6.94192113501492 8.47108987216073 -0.819483825549856 0.413255256558454 -22.2364566622044 15.4581477483451 -1.43849425068311 0.151487329262846 ARHGDIG other 1 1 1 -0.819483825549856 -1.43849425068311 0.000259410264363665 7.03171707248613 1.97655506023929 3.55756194903816 0.000442250576977189 -0.11708414682974 2.82977971184665 -0.0413757107451072 0.967027069370243 TCP10L other 1 1 1 3.55756194903816 -0.0413757107451072 4.19562651103604e-16 302.888528904625 44.7571256503186 6.76738116006494 8.081515436652e-11 -307.040435381154 101.767389889131 -3.0170807732777 0.00279485208554457 ARFGAP3 other 5.70563249235790e-12 1 1.08316551397447e-06 6.76738116006494 -3.0170807732777 1.74766598813494e-05 13.2322751173178 2.97225614213687 4.45192960651252 1.2431035987976e-05 -13.1842436064153 9.80553446470554 -1.34457164511238 0.179883791087989 BGLAP other 0.140320102187354 1 0.126697118789452 4.45192960651252 -1.34457164511238 0.0821338794670546 -2.56370372195947 1.70272411081221 -1.50564833473614 0.133317850299502 -9.21577579945892 4.3064134111937 -2.14001186590778 0.0332434903710573 LINC00996 other 1 1 1 -1.50564833473614 -2.14001186590778 6.0233014586634e-43 323.332523423943 21.5553070788378 15.0001353375002 4.2035207173097e-37 -302.870078702602 85.2601027253332 -3.55230722250362 0.000452998821747224 C22orf39 other 9.57162834796202e-39 1 6.67140773044222e-33 15.0001353375002 -3.55230722250362 0.000119506698050719 963.521571070377 224.756164505159 4.28696393352211 2.53845692088639e-05 163.042964990423 1021.22733860405 0.159653936814198 0.873275307179134 PEG10 other 0.876223110107874 1 0.252170310520854 4.28696393352211 0.159653936814198 5.02077711187847e-08 102.871623693024 18.5715911905862 5.53919277230101 7.1663757262813e-08 -77.889691567164 81.8863285281231 -0.95119286658961 0.342350917732945 STAG3L5P other 0.000489827015034863 1 0.000853587012757365 5.53919277230101 -0.95119286658961 0.0449961802611432 1548.99980285855 619.528914644397 2.50028653424135 0.0130004554441675 1399.26540715185 949.559457251465 1.47359430361747 0.141751445933932 UGT1A8 other 1 1 1 2.50028653424135 1.47359430361747 1.18754941647049e-16 991.871555572528 120.258760740357 8.24781121530113 7.59177264186624e-15 -1193.57109295191 530.861116951971 -2.24836789668266 0.0253748363263372 EIF6 essential 1.63513679153821e-12 1 1.10786738162754e-10 8.24781121530113 -2.24836789668266 0.908789103113282 0.567455631968414 1.4101809082144 0.402399173512381 0.687711042979994 1.44398977289457 7.00255760640807 0.206208910237763 0.836784293019482 GTF2A1L other 1 1 1 0.402399173512381 0.206208910237763 1.14616769797581e-20 377.053855922421 63.5547435196384 5.93274136659699 9.31631611311495e-09 -395.096125935944 99.6985247415525 -3.96290844784462 9.53538919220003e-05 MRPL20 essential 1.68945118681634e-16 1 0.000115848390866584 5.93274136659699 -3.96290844784462 1.23276891124622e-05 166.834600626192 43.5547690850548 3.83045540432997 0.00015885733709338 -151.326461310295 92.892493051484 -1.62904941335168 0.104460134708603 ARPIN other 0.10018712941698 1 1 3.83045540432997 -1.62904941335168 1.02512823146399e-08 603.161187473063 95.9881658506153 6.28370364334029 1.41362721644527e-09 299.600395339699 1029.97261377686 0.290881904365476 0.77137716301925 LINC01206 other 0.000104378556527664 1 1.81764187490532e-05 6.28370364334029 0.290881904365476 0.0171024408142112 1999.74859536717 699.444735875998 2.85905160593231 0.00457931023542969 1917.0104704014 1072.04740259303 1.78817696471685 0.0748645559286754 UGT1A10 other 1 1 1 2.85905160593231 1.78817696471685 0.000509769668288023 10.7944912367871 9.04585857755986 1.19330753893999 0.233792582661773 -58.6187541572167 19.8252834143412 -2.95676752418142 0.00338273883136254 LINC00960 other 1 1 1 1.19330753893999 -2.95676752418142 0.274498315802871 23.8675677847261 85.5499528112559 0.278989841611998 0.780464621450728 -189.429174381906 151.505616229385 -1.25031123661517 0.212260448069219 SERPINB10 other 1 1 1 0.278989841611998 -1.25031123661517 0.350780596365113 -27.9213475640302 130.641104684272 -0.213725592963328 0.830920583755356 320.478078552234 256.638186334882 1.24875445516923 0.212824659851605 HLA-DMB other 1 1 1 -0.213725592963328 1.24875445516923 6.53451147606824e-06 72.0791807388041 22.6949595477537 3.17599952479045 0.00167051296247477 -59.006981346663 41.3893194437632 -1.42565720189812 0.155148609419992 DECR2 other 0.0542821868316988 1 1 3.17599952479045 -1.42565720189812 1.25214192731244e-12 184.388470414701 37.8419057314623 4.87260001447014 1.87297478441838e-06 -236.737138329333 73.3223979776398 -3.22871516561049 0.00139600189732075 GNG10 other 1.53725464416148e-08 1 0.020377965654472 4.87260001447014 -3.22871516561049 5.64914857711997e-06 22.3234596502841 5.30538480417444 4.20769849393758 3.51100306456758e-05 -1.59054553477856 8.09163595394948 -0.196566620622894 0.84431402268266 CCDC169 other 0.0472212329561458 1 0.344183630419559 4.20769849393758 -0.196566620622894 0.0014813036708605 6.02277047505791 1.69238115384089 3.55875534384741 0.000440871746005347 -0.2923522083645 6.30897482271638 -0.0463390989153806 0.963074616272674 LINC00882 other 1 1 1 3.55875534384741 -0.0463390989153806 0.287069367916694 12.2564199055933 11.2593047670629 1.0885592102851 0.27732260296396 -19.3855747441446 28.749555404388 -0.674291288037999 0.50070518484013 ZNF702P other 1 1 1 1.0885592102851 -0.674291288037999 6.53609636515299e-08 197.178627466312 38.3389814296718 5.14303249886836 5.17785274077337e-07 -189.902261144561 106.698935189167 -1.77979527919265 0.0762258691545689 AP5Z1 other 0.000633347737783324 1 0.00584734910015536 5.14303249886836 -1.77979527919265 1.61937082976522e-14 181.893669804805 21.7692965093126 8.35551436983707 4.17274656471205e-15 352.996748270389 233.588995342142 1.5111874074091 0.131974085356731 SOX2-OT other 2.1113356878479e-10 1 6.11349099195962e-11 8.35551436983707 1.5111874074091 0.36653783352812 1.653407101369 3.99991114570681 0.41336095756618 0.679670283590531 -7.1045944364614 7.2159343170211 -0.984570275217574 0.325716643067607 STRC other 1 1 1 0.41336095756618 -0.984570275217574 3.51634542565531e-07 29.8895275385518 19.1903423423163 1.55752966806866 0.120516126062104 -125.486038646878 31.531122429176 -3.97975171764785 8.87113046970577e-05 EIF4EBP3 other 0.00325156461510347 1 1 1.55752966806866 -3.97975171764785 0.000811209701380824 21.162505517577 5.54063702762169 3.81950765084876 0.000166210326337172 17.0751891292786 35.3829034462185 0.482583040570219 0.629785756119664 ARHGEF26-AS1 other 1 1 1 3.81950765084876 0.482583040570219 0.0378470152009568 1572.8181370133 613.00493061063 2.56575120113076 0.0108334921314748 1467.16031980724 939.560068051404 1.56153967127407 0.119563462308788 UGT1A3 other 1 1 1 2.56575120113076 1.56153967127407 0.788242190791137 3.69854294621611 10.7861570146071 0.342897191391462 0.731947648002795 -15.2059421932306 33.1367544216499 -0.458884476124065 0.646693274576822 PSG4 other 1 1 1 0.342897191391462 -0.458884476124065 3.30275747938879e-09 195.723965987476 30.3723112373587 6.44415778759471 5.2378984503429e-10 84.9364582092122 113.60371033615 0.747655670381606 0.455311395356551 MRPL33 essential 3.45996873540769e-05 1 6.83336231831735e-06 6.44415778759471 0.747655670381606 3.11179529375658e-14 530.67296149837 77.4254654482901 6.85398477653052 5.12602639933594e-11 -431.69772702172 222.601552746505 -1.93932936089323 0.0535347193506338 MICAL3 other 4.03008608494414e-10 1 6.91398440742432e-07 6.85398477653052 -1.93932936089323 6.80751697105192e-19 231.174470364199 37.3659129606076 6.18677430972745 2.23738394603774e-09 -314.320451479807 79.3255892397611 -3.96240928674069 9.47773243541947e-05 PPAN-P2RY11 other 9.79533616964661e-15 1 2.85288826959272e-05 6.18677430972745 -3.96240928674069 0.00147081317196429 119.090547401619 39.3817535773779 3.02400316348605 0.00273284978144263 -29.0934550936593 68.5628045306113 -0.424332920638768 0.671658454201524 PCDHAC2 other 1 1 1 3.02400316348605 -0.424332920638768 6.49832368076177e-05 125.654345609673 28.120917516567 4.46835867057488 1.16216567176541e-05 33.5463239546627 139.906213081148 0.239777228014923 0.81068556841307 STON1 other 0.492377985291319 1 0.118738466684272 4.46835867057488 0.239777228014923 0.0581171997734152 2.47691226096738 5.58797033394889 0.443257947509002 0.657931516951932 49.5697975253093 20.8264669563354 2.38013474053169 0.0179956300642174 VSIG8 other 1 1 1 0.443257947509002 2.38013474053169 1.52661341495849e-08 126.893610399362 26.1090133880578 4.86014574788194 2.04721327549871e-06 -173.49141909158 79.7827164398794 -2.17454891025571 0.0305799010489416 KCTD7 other 0.000153684172483871 1 0.0222061223993345 4.86014574788194 -2.17454891025571 0.011721278581088 51.6682798661024 18.5916848171769 2.77910691656982 0.00583511607632186 -60.0158450410291 62.267471946026 -0.963839435990775 0.335992079031699 EFNA4 other 1 1 1 2.77910691656982 -0.963839435990775 2.3387087266368e-17 40.9051016623987 6.39562304587716 6.39579621390719 7.07636829467671e-10 -31.9181573161009 10.4784727177044 -3.04606961109629 0.00254969991727131 MRPS31P5 other 3.27582931340016e-13 1 9.19149477795558e-06 6.39579621390719 -3.04606961109629 0.015047631401299 24.0131778425655 14.2992130921242 1.67933561713208 0.0942307102321955 -30.7875487777534 23.3889068959663 -1.3163312383386 0.18916698762286 TICAM2 other 1 1 1 1.67933561713208 -1.3163312383386 0.212612610798944 5.41606503424389 3.75291776450686 1.44316112798053 0.150125735970878 -1.82438436489616 7.26730399848365 -0.251040050791438 0.80197268448055 PALM2 other 1 1 1 1.44316112798053 -0.251040050791438 0.0486601452697024 6.70046263685752 4.2073266233125 1.59257011322362 0.112413824401638 -11.8467130401679 11.398307024735 -1.03933970320854 0.299566398213949 C4orf48 other 1 1 1 1.59257011322362 -1.03933970320854 2.11736221682496e-06 50.0720461095099 10.6767995842954 4.68979919630236 4.33298913863786e-06 -16.7220461095105 25.3260047727693 -0.66027177438939 0.509638190218983 NAT6 other 0.0183554130576556 1 0.0458300261193727 4.68979919630236 -0.66027177438939 0.0304474616724337 10.5513499626139 4.32993613559398 2.4368373186563 0.0154724703034732 1.765051122737 11.0451673670453 0.15980302190832 0.873157521168762 MNX1-AS1 other 1 1 1 2.4368373186563 0.15980302190832 0.868322869724331 -0.841033839595003 3.90963576426856 -0.215118208013515 0.829838160231507 -2.85998867572608 5.52713120230258 -0.517445410837112 0.6052705027742 AMY2A other 1 1 1 -0.215118208013515 -0.517445410837112 0.898059819342608 15.7023940103691 57.2546216223507 0.274255484805077 0.784097228605599 -46.259614367259 160.327638276673 -0.288531752007911 0.773160296258545 TNFRSF6B other 1 1 1 0.274255484805077 -0.288531752007911 0.173378328414682 -163.063775475493 139.593991455569 -1.16812889849484 0.243785199157702 -822.868922532889 467.255968510448 -1.76106669146697 0.0793590579106619 UPK3B other 1 1 1 -1.16812889849484 -1.76106669146697 0.000499621379350451 87.2106122169219 59.5989956889297 1.4632899633428 0.144573130299375 -210.3345292229 85.6939615840936 -2.45448483574299 0.0147521597454062 IL10RB other 1 1 1 1.4632899633428 -2.45448483574299 0.40669949130833 250.654829227465 323.114454579703 0.775746258561874 0.438570308678863 -425.89829131845 619.125712353349 -0.687902768081743 0.492098069423363 CFB other 1 1 1 0.775746258561874 -0.687902768081743 8.77964222497302e-09 55.3885850659672 8.83328300936146 6.27044157956523 1.42810874052428e-09 43.819658842231 45.5245999130641 0.96254901582685 0.336638342643255 WDR92 other 8.97718417503491e-05 1 1.83583378594396e-05 6.27044157956523 0.96254901582685 8.42763298512147e-09 2700.7493856007 482.676886790508 5.59535676870495 5.38313833809623e-08 -1055.36390197274 1055.055082892 -1.00029270422536 0.318061194502689 NME2 other 8.62736788686885e-05 1 0.000645761275038024 5.59535676870495 -1.00029270422536 0.000114515953037694 38.0101726902535 9.37551832955251 4.05419427003218 6.62480022359614e-05 -22.0296933299185 34.9464037610145 -0.63038513148796 0.528987912887546 DUBR other 0.842379350545279 1 0.632999661364611 4.05419427003218 -0.63038513148796 0.000403193141532106 60.0803927655607 71.3556718764985 0.841984823148285 0.400544376761143 -365.229488276916 123.826664867804 -2.94952212971924 0.00346261893279142 PLA2G4B other 1 1 1 0.841984823148285 -2.94952212971924 0.0134396227815914 21.4685189536021 16.8637047735227 1.27306064959755 0.204091548603231 -55.1508777741565 31.5525847567574 -1.74790364083707 0.0816174237862587 CFAP57 other 1 1 1 1.27306064959755 -1.74790364083707 1.86957507253535e-22 208.522379603399 27.8914265590409 7.47621779624632 1.0626834059963e-12 -143.052804532578 49.3494066971097 -2.89877455691796 0.00405273128139703 TTC4 essential 2.80941046149886e-18 1 1.49593943062099e-08 7.47621779624632 -2.89877455691796 0.240561058937186 37.167494571521 34.6189860579505 1.07361592015735 0.283953429988312 -61.7476129569595 70.706078253442 -0.873299926713918 0.383275643758413 RPLP0P2 other 1 1 1 1.07361592015735 -0.873299926713918 0.000256113937309057 14.9976808856151 32.9218619880923 0.455553847198549 0.64907562916493 -154.095596689911 47.3026674487972 -3.25765131230097 0.00126655177564552 TMEM35B other 1 1 1 0.455553847198549 -3.25765131230097 0.986785074539272 11.8849870816074 76.2267128212671 0.155916300752398 0.876214224374452 14.5347683166614 148.065293223616 0.0981645867185783 0.921873637323224 HLA-L other 1 1 1 0.155916300752398 0.0981645867185783 0.00408898965500746 9.98371145535594 3.2713612943114 3.05185228935633 0.00249843748925053 14.7037108783326 6.47860877180111 2.26957845368471 0.0240133014251729 OSTCP1 other 1 1 1 3.05185228935633 2.26957845368471 9.61827240686242e-11 58.3670613854617 29.1890195712771 1.99962390798822 0.0465464494885793 -244.699563369312 50.820545185972 -4.81497320569588 2.45952661997514e-06 JMJD7 other 1.09532886169349e-06 0.0382899104197731 1 1.99962390798822 -4.81497320569588 0.142071593127611 21.0074925074925 13.0313644419004 1.61207159857689 0.108101786048956 -19.0541911791912 32.772499020735 -0.581407941064724 0.561445275196517 APOBEC3D other 1 1 1 1.61207159857689 -0.581407941064724 0.879591458882285 1.71437361659127 6.61849166874341 0.25902784235381 0.795809679113457 -4.86016865556732 16.858489988708 -0.288292050997611 0.773342752848887 WDR86-AS1 other 1 1 1 0.25902784235381 -0.288292050997611 0.09661415100194 -1.26609707630256 8.76012911066899 -0.144529499543629 0.885190186454692 -24.6863760226431 12.9973721383657 -1.89933593959149 0.0585860271110659 TUBA4B other 1 1 1 -0.144529499543629 -1.89933593959149 2.44926112591698e-09 208.296051242345 53.0993588906541 3.92276019134775 0.000111199606629633 -195.553551687445 75.9326148220956 -2.57535648081674 0.0105482862809575 MRPS6 essential 2.59009364065721e-05 1 1 3.92276019134775 -2.57535648081674 0.135594198475877 72.0375359124068 37.6620102817861 1.91273740762705 0.0568279006864366 88.1827246428621 140.869888804064 0.625987039469561 0.53184644930119 ZNF512 other 1 1 1 1.91273740762705 0.625987039469561 0.935669373890539 47.6063374533842 376.874291443933 0.126318877498882 0.899575300416345 -253.841658296806 900.345357744648 -0.281938098656582 0.778211028276411 GSTA1 other 1 1 1 0.126318877498882 -0.281938098656582 0.000134992736808763 77.8304814162653 49.8924322327294 1.55996566880555 0.119935002108371 -383.524205980989 117.928577413978 -3.25217359855586 0.00129027041421065 ACY1 other 0.984232044072691 1 1 1.55996566880555 -3.25217359855586 1.52770458431988e-28 230.155594002306 19.1006174570845 12.0496415636522 5.43418810608326e-27 -132.489949734433 82.2057791587815 -1.61168656376976 0.108211583223826 NFS1 essential 2.37848326732762e-24 1 8.52950165130829e-23 12.0496415636522 -1.61168656376976 3.67925712625098e-07 33.1386727358695 10.3121501119244 3.2135560844435 0.00146954517698856 -65.1674106248443 22.6005411014596 -2.88344470746479 0.00424902683736356 FAM86DP other 0.0033952184761044 1 1 3.2135560844435 -2.88344470746479 2.26376999370977e-20 1350.72716749247 332.094516559419 4.06729741125008 6.22871068990716e-05 -2557.2270546534 486.999186460068 -5.25098835018913 3.04657459489549e-07 DDOST essential 3.32411985876343e-16 0.00479683169966295 0.596772771200005 4.06729741125008 -5.25098835018913 4.64479624927949e-06 14.1683026312844 3.31480049469384 4.27425501292288 2.67448463082971e-05 -4.92884706309998 5.96638934725102 -0.826102149262336 0.409486484577093 LINC01011 other 0.0391556323814261 1 0.265175151146766 4.27425501292288 -0.826102149262336 0.959066022359111 1.72527055974479 45.0707731996863 0.0382791427185189 0.969493941229698 -27.8091989237829 107.673201227992 -0.25827409798004 0.796395849237138 GSTA2 other 1 1 1 0.0382791427185189 -0.25827409798004 0.794711389730643 -95.4149989362423 142.204839632947 -0.670968717960115 0.50280981851986 -68.5833607331622 488.066605743099 -0.140520494387731 0.888352765376089 SPRR2F other 1 1 1 -0.670968717960115 -0.140520494387731 5.80744021961915e-12 170.842575927928 35.777216420342 4.77517797697619 2.93763558290194e-06 -212.384403509506 69.3218602551361 -3.06374356844774 0.00240526387088115 DNAJC25-GNG10 other 6.94337552657665e-08 1 0.0314885158131259 4.77517797697619 -3.06374356844774 0.0531064764899111 1771.23780187284 745.405001174266 2.37620863702623 0.0181867883129088 1980.01373418761 1142.49125685092 1.73306685921184 0.0842213091193216 UGT1A7 other 1 1 1 2.37620863702623 1.73306685921184 0.000747150355159762 59.5394472417916 28.723023123259 2.07288233506238 0.0391214471505788 -164.919201956033 68.43153962866 -2.40998818455581 0.0166146871639529 FLNB-AS1 other 1 1 1 2.07288233506238 -2.40998818455581 3.18329970620545e-14 108.178362294692 18.7161375978188 5.77995121746161 2.03651170335936e-08 -105.533650718083 39.7332361397033 -2.6560547534317 0.00837115428315132 P2RY11 other 4.1214181296242e-10 1 0.000248983920852716 5.77995121746161 -2.6560547534317 1.24923716046605e-06 296.915275865011 70.627680470991 4.20395054580567 3.5660402762952e-05 -196.307355181533 132.525686009223 -1.48127778918172 0.139694310361069 TMEM141 other 0.011040758024199 1 0.349400626271404 4.20395054580567 -1.48127778918172 0.359155553646219 4.6106218669557 3.74678202784677 1.23055513576416 0.219564241597449 -8.17277092835961 17.0105317580581 -0.480453582792207 0.631295389297437 TMEM225B other 1 1 1 1.23055513576416 -0.480453582792207 0.0975882061414537 -63.3134527587987 55.1020669571021 -1.14902137533406 0.251552860315248 -173.292847761848 81.2407160652453 -2.13307878309042 0.0338101593331272 IFITM10 other 1 1 1 -1.14902137533406 -2.13307878309042 2.7372305928904e-05 101.847058313623 33.1204359135062 3.07505186766247 0.00231888512994082 -288.139458183184 113.13684099039 -2.54682255276739 0.0114221644111804 DBNDD2 other 0.215365303048617 1 1 3.07505186766247 -2.54682255276739 0.241905079535648 -18.0775296140407 13.0363910562722 -1.38669740237218 0.166665329248397 14.6845448760174 31.0587192494932 0.472799433809785 0.636734050548827 FAM3D-AS1 other 1 1 1 -1.38669740237218 0.472799433809785 2.14174180322501e-06 225.616585336145 43.9271661817784 5.13615161065714 5.41484248830767e-07 -172.593063686493 423.334236202187 -0.40769928091538 0.683821174270458 ETV5 other 0.0185603344667479 1 0.00610902529530871 5.13615161065714 -0.40769928091538 0.0232418267826047 -22.0103606305636 11.2572405330113 -1.95521811637758 0.0516083494330531 -68.0182834657005 31.3472871347174 -2.16982998156704 0.0309084045737696 CFHR1 other 1 1 1 -1.95521811637758 -2.16982998156704 2.37124649846754e-08 239.672579172493 40.1598706024479 5.96796193755376 7.6444628261629e-09 -4.43033182351115 171.044673279801 -0.0259016065134274 0.979355239394687 RBM12 other 0.000236176151247367 1 9.53646737563822e-05 5.96796193755376 -0.0259016065134274 0.0325545855347246 1658.88794972893 632.221102907391 2.62390474171173 0.00918566711326435 1556.50912326817 969.012927643981 1.60628313499656 0.109376256897997 UGT1A4 other 1 1 1 2.62390474171173 1.60628313499656 0.913281500925238 -2.72157606364756 7.96758573063174 -0.34158102035656 0.732928997377798 -7.35665841040854 20.3683833919087 -0.361180279694213 0.718244030404456 LILRA6 other 1 1 1 -0.34158102035656 -0.361180279694213 8.74374230117725e-18 137.731222767597 14.7090798549484 9.36368720041051 4.67853678843631e-18 33.6727731789176 62.2160960005382 0.541222856198278 0.588835934324229 SCARF2 other 1.23435410065719e-13 1 7.07301191675801e-14 9.36368720041051 0.541222856198278 7.99902388684308e-07 204.764235764235 68.8782159330221 2.97284465038046 0.00321386858750851 -583.981203981206 173.221405500478 -3.37129930503649 0.000856263014971622 APOBEC3C other 0.00717672423127561 1 1 2.97284465038046 -3.37129930503649 0.992987398538645 0.471755725190818 4.00729897434612 0.117724114973926 0.906373143149911 0.262701115678141 10.5333519253006 0.0249399353160456 0.980121160286968 CCDC13 other 1 1 1 0.117724114973926 0.0249399353160456 0.000990123310087513 -2.44156360572874 28.9481650108221 -0.084342603574906 0.93284608296472 503.64021855819 134.111741034308 3.75537752827583 0.00021170066415174 ASPRV1 other 1 1 1 -0.084342603574906 3.75537752827583 5.50300956769808e-19 506.111500730484 61.5540970182279 8.22222281289595 8.46898150013173e-15 -668.311071153028 204.869986621073 -3.26212288181155 0.00124803396678099 UBE2V1 other 7.93148768992324e-15 1 1.23494688234921e-10 8.22222281289595 -3.26212288181155 0.0411560818571691 21.0805588919066 15.7800388846734 1.3359003134258 0.182723665272263 -62.4407454324421 41.585579693646 -1.50149994042244 0.134412411376761 CTAGE8 other 1 1 1 1.3359003134258 -1.50149994042244 0.80431003344977 -2.76972934981837 4.36177163043701 -0.635001000623426 0.52596550403028 -4.12502752288225 11.0383442553594 -0.373699843695257 0.708920906766982 PTCHD4 other 1 1 1 -0.635001000623426 -0.373699843695257 0.0742172957786872 -345.310279373521 233.432733318932 -1.47927102794849 0.140287822840964 -980.49152514027 445.451984658864 -2.2011160773953 0.0286137274975071 C4A other 1 1 1 -1.47927102794849 -2.2011160773953 0.266683836236553 -715.183897105897 815.00810172871 -0.87751753091647 0.380977184611128 -2005.07935772605 1236.25350947477 -1.62189983070537 0.105979079767539 HBB other 1 1 1 -0.87751753091647 -1.62189983070537 0.0130236429321802 2.88477446954542 1.26640354389171 2.27792671890382 0.0235069122319649 -3.7498073641771 3.67594504570693 -1.02009342292982 0.308590599478281 CRYBB2 other 1 1 1 2.27792671890382 -1.02009342292982 8.92770006650962e-12 150.352020326982 68.9750391639662 2.17980333392153 0.030136036478368 -535.283586695563 106.948854325601 -5.00504273814767 1.00862306590307e-06 N4BP2L2 other 1.06087859890334e-07 0.0157950372120421 1 2.17980333392153 -5.00504273814767 0.000456511439159286 132.647544806604 52.4166171764802 2.53063917421448 0.0119540100269039 -170.973576035209 100.125783222167 -1.70758790126855 0.0888623272080551 MIR4712 other 1 1 1 2.53063917421448 -1.70758790126855 1.54990263924696e-11 21.2410476710087 2.9918232590643 7.09970002628159 1.13910088140807e-11 -15.8738238785634 19.8431632599848 -0.799964384235758 0.424445257836166 LIFR-AS1 other 1.8262502798247e-07 1 1.56478288079026e-07 7.09970002628159 -0.799964384235758 6.7315658557955e-09 94.4708173645565 28.7342586863597 3.28774159082107 0.00114332171964365 -162.773540102005 47.1481494401557 -3.45238449514567 0.000644491231727927 LINC00847 other 6.93014704854147e-05 1 1 3.28774159082107 -3.45238449514567 0.447029486271628 -21.5388900073822 30.163171607593 -0.714079085833277 0.475818832487669 -83.1586023309399 66.1050546012461 -1.25797645630221 0.209528863764628 IGFBP7-AS1 other 1 1 1 -0.714079085833277 -1.25797645630221 0.139896086453306 -87.4011637560371 45.9428819442142 -1.90238748762351 0.0581805260020609 46.9171616842743 208.55371649286 0.224964399931375 0.822176507234696 A2M-AS1 other 1 1 1 -1.90238748762351 0.224964399931375 6.3788178581537e-11 27.5919566443807 7.69224771057774 3.58698233371224 0.000397276011824578 -26.993506926523 11.2420693854545 -2.40111548870606 0.0170243011662271 SMARCA5-AS1 other 7.32224501937464e-07 1 1 3.58698233371224 -2.40111548870606 0.0189515260224392 7.10957417890018 2.56416595087828 2.77266538714665 0.00594707084615297 -1.41098520002538 11.1006115198905 -0.127108781124096 0.898948912123054 RNF139-AS1 other 1 1 1 2.77266538714665 -0.127108781124096 0.339832959134025 -4.95395484076145 3.76025817661254 -1.31745071962698 0.188821228845868 -13.773569826657 16.2713275128334 -0.846493306449248 0.398038495576019 LINC00861 other 1 1 1 -1.31745071962698 -0.846493306449248 1.10416757194631e-07 10.6403457028457 1.83325504793352 5.80407276927435 1.80449700086429e-08 5.94123587873587 11.501714877205 0.516552178711253 0.605890064351823 ARNTL2-AS1 other 0.00105481128148031 1 0.000221213287335953 5.80407276927435 0.516552178711253 0.000139950689446218 2.99129087444997 0.898351031624483 3.32975726542089 0.000989356224577505 -1.97971373662861 1.76359310516205 -1.12254563188865 0.262620415674309 RORA-AS1 other 1 1 1 3.32975726542089 -1.12254563188865 2.62386042301417e-07 36.7984040743909 11.3385760351154 3.24541670492194 0.00131953549120754 -43.7187538623869 17.9095260078105 -2.44108938691738 0.0152810169106833 SCAMP1-AS1 other 0.0024449131421646 1 1 3.24541670492194 -2.44108938691738 0.0251755116164817 5.77471137353742 4.97697452743314 1.1602854990933 0.246972900758418 -15.8032071285391 9.63061912131525 -1.64093366474874 0.101993037554998 BDNF-AS other 1 1 1 1.1602854990933 -1.64093366474874 2.19519021302626e-09 9.05758120679615 1.40294150059906 6.45613605622795 4.99203449445854e-10 1.41176508146944 9.11346613911497 0.154909785137639 0.877008607816243 DDX11-AS1 other 2.32931633504216e-05 1 6.51809943941452e-06 6.45613605622795 0.154909785137639 2.8041856280084e-17 87.6391323588435 9.68421652364074 9.04968741094359 2.91977228505222e-17 -12.44858641494 41.9727693105183 -0.296587206882736 0.767009695460055 ZNF585B other 3.91969067083014e-13 1 4.38111831372086e-13 9.04968741094359 -0.296587206882736 2.87344231443674e-11 326.153250247403 47.9651913935414 6.79979044743935 6.88295894677165e-11 -140.729759401286 171.488990971682 -0.820634366112307 0.412589370270469 CEBPA other 3.34727295208736e-07 1 9.24587875319835e-07 6.79979044743935 -0.820634366112307 5.85907817496327e-05 7.13431037944187 5.49878402468547 1.29743418679732 0.195585196434372 -29.1422062930044 9.55409301376673 -3.05023263338682 0.00251320080799291 RAD51-AS1 other 0.445758667551205 1 1 1.29743418679732 -3.05023263338682 0.186349163475142 -4.43385528847003 2.9574844557322 -1.49919817156649 0.134981950350893 -7.74449687590543 4.66576915558224 -1.65985427432468 0.0980961873068417 MEF2C-AS2 other 1 1 1 -1.49919817156649 -1.65985427432468 1.97120526169937e-13 40.8252639958964 14.4601567669596 2.82329331927986 0.00510452852605012 -120.330907031709 23.1054795479536 -5.20789481049165 3.77415545118927e-07 LINC01184 other 2.49002648657864e-09 0.00593712394026584 1 2.82329331927986 -5.20789481049165 6.65336000229491e-17 91.5373417976757 11.3054018940072 8.09677910222703 1.94802166391191e-14 -12.2856396314045 24.5008755987416 -0.501436758122862 0.616472370503164 RAB30-AS1 other 9.22621431518235e-13 1 2.82580022567062e-10 8.09677910222703 -0.501436758122862 0.0860060838821212 18.2985109152661 8.56338074585111 2.13683257329549 0.033507122996387 -10.4871483380015 41.868773527009 -0.250476607136255 0.802408581611191 NUDT16P1 other 1 1 1 2.13683257329549 -0.250476607136255 4.7214748168259e-22 56.8521606833242 5.91391529868257 9.61328625994846 5.23929179824133e-19 -14.5259549388313 14.8843142084027 -0.97592369627825 0.329975841234103 KCTD21-AS1 other 7.07135283316016e-18 1 7.97367818774348e-15 9.61328625994846 -0.97592369627825 0.0814549529881217 2.76514772014782 2.92058746756768 0.946777917406694 0.344598513441134 -9.62474727879625 6.61864851498069 -1.45418619178999 0.147056136686442 LINC01550 other 1 1 1 0.946777917406694 -1.45418619178999 0.487681889215104 6.36447212949342 5.81524642074315 1.09444581863138 0.274776266355351 -8.23873179496184 24.6726491311324 -0.333921653535211 0.738708884498789 CASC8 other 1 1 1 1.09444581863138 -0.333921653535211 4.29690386640899e-07 18.6298208401912 3.80420456079926 4.89716589695615 1.66705281143569e-06 -22.5568285598296 15.2160669005082 -1.48243489643675 0.139378018704622 UBR5-AS1 other 0.00394541713013673 1 0.0181992155424434 4.89716589695615 -1.48243489643675 3.18561326551807e-10 65.5166338723756 20.6104750864175 3.17880270094073 0.00165099996675565 -95.5769688519393 32.176212631591 -2.97042321127939 0.00324150793102392 SBF2-AS1 other 3.53603072472505e-06 1 1 3.17880270094073 -2.97042321127939 0.00429144921631935 7.62956314175498 5.69470395553177 1.33976466578982 0.181448380971769 -15.3051404024631 9.68860989753124 -1.57970447405082 0.115345334892736 EXTL3-AS1 other 1 1 1 1.33976466578982 -1.57970447405082 1.27314199763855e-13 24.504091671066 3.2397043224628 7.56368150672409 6.05609823956786e-13 -4.48517207795907 10.3947024773318 -0.431486335250102 0.666456582011727 LACTB2-AS1 other 1.61752690799978e-09 1 8.57059022863643e-09 7.56368150672409 -0.431486335250102 0.440808804012067 6.75101553166063 5.27545314147026 1.2797034398033 0.201785808503031 5.98835125448026 16.1541525901175 0.370700426473853 0.711161356189472 LINC00968 other 1 1 1 1.2797034398033 0.370700426473853 0.634712373383728 0.918179795180853 1.76553505937249 0.520057526077787 0.603448041926661 7.35302724774457 8.34079921829736 0.881573462602254 0.378788730090232 CACNA1C-AS1 other 1 1 1 0.520057526077787 0.881573462602254 0.0103664794780852 244.084175899251 81.0856575977444 3.01020159582501 0.0028568121687584 405.555926741826 343.826136219594 1.17953780710494 0.239218538357545 H2AFJ other 1 1 1 3.01020159582501 1.17953780710494 0.381632495563663 152.577678278912 189.686216517374 0.80436882067779 0.421883902004239 -193.558046667394 312.745637818565 -0.618899269123249 0.536498801485089 STARD4-AS1 other 1 1 1 0.80436882067779 -0.618899269123249 0.154271227820644 3.94901549986456 5.64101453790642 0.700054125605955 0.484494023540944 -15.3991119616028 11.1309318770915 -1.38345217917429 0.167664816775198 UBAP1L other 1 1 1 0.700054125605955 -1.38345217917429 0.526318877400859 2.95633947667158 12.8487112214372 0.230088405422261 0.818196656195595 -29.6447373571664 29.4449871908382 -1.00678384286716 0.314936744517796 SOCS2-AS1 other 1 1 1 0.230088405422261 -1.00678384286716 4.82797635779218e-07 444.68822748293 86.3490137559752 5.14989353253799 5.03107598097136e-07 -150.377437216229 177.721998020138 -0.846138569740755 0.398224721345972 PGAM5 other 0.00441518437920095 1 0.00568561896609573 5.14989353253799 -0.846138569740755 0.00443971826302812 14.3944409929162 4.7944308421868 3.00232529506062 0.00292742545901441 -14.8941291065815 19.1834038806564 -0.776407002596655 0.438180856232625 BAALC-AS1 other 1 1 1 3.00232529506062 -0.776407002596655 0.14458990974179 38.7799803798737 29.2977591613749 1.32365005003522 0.186730703058058 -10.1246185303819 47.2105761588446 -0.21445657634672 0.830351714610717 MIR210HG other 1 1 1 1.32365005003522 -0.21445657634672 2.21758239256041e-08 25.3053341980018 4.57317587836337 5.53342685063272 7.44726199788895e-08 -1.46077466428319 8.59339173513192 -0.169988138479849 0.865147237177696 UBL7-AS1 other 0.000221115140362199 1 0.000886373122988742 5.53342685063272 -0.169988138479849 3.60081628978137e-08 97.6911067891631 22.3957999059566 4.36202802308393 1.8399884899061e-05 -30.6495690348831 35.5048280788722 -0.86325073780942 0.38877149645767 ZBED5-AS1 other 0.000354392339240283 1 0.184955643005361 4.36202802308393 -0.86325073780942 2.13022270849099e-29 232.754611699812 18.2415628414262 12.7595762338538 2.28340161284077e-29 -47.8814767503749 69.1853215098732 -0.69207565572333 0.489498054751897 ZCCHC3 other 3.32975111564227e-25 1 3.59795592135319e-25 12.7595762338538 -0.69207565572333 1.92201371764438e-06 20.9862253615401 7.30708736873296 2.87203701044279 0.00441327614552236 -30.333444892639 12.7271412916979 -2.38336671192815 0.0178708148430017 DNAJC3-AS1 other 0.0167388174669649 1 1 2.87203701044279 -2.38336671192815 3.86312237700216e-07 21.0795264744037 7.53070993775204 2.79914199971113 0.00548925217749834 -33.3525576116795 11.8190980767284 -2.82192070792189 0.00512448039360753 CKMT2-AS1 other 0.00355909464593209 1 1 2.79914199971113 -2.82192070792189 7.73254846906255e-06 10.0542424397409 54.0451527170268 0.186034120254662 0.852557178244012 -589.13909854092 127.744182650994 -4.61186635911623 6.15816063944019e-06 TWF2 other 0.0639404432906782 0.0951066329155143 1 0.186034120254662 -4.61186635911623 2.93070247221504e-15 132.028487165426 15.509234893231 8.51289493481395 1.21162735566987e-15 19.3326205201004 38.6511608633966 0.500182144293855 0.61735576304103 MARS2 essential 3.90105806076544e-11 1 1.78618104772852e-11 8.51289493481395 0.500182144293855 0.00134791043548756 25.3658198934036 7.04813264295421 3.59894190112341 0.000380733422049197 13.966290579359 15.1191471520398 0.923748571193365 0.356451287553714 LRP4-AS1 other 1 1 1 3.59894190112341 0.923748571193365 9.63658634487605e-20 16.3368597986617 2.24830864623787 7.2662887393145 3.91487666091756e-12 -3.25583502633331 3.58402889301319 -0.908428788808128 0.36445589702759 STX18-AS1 other 1.4035688011312e-15 1 5.44167855867541e-08 7.2662887393145 -0.908428788808128 0.0379108516724657 -37.641914191419 14.6243035829173 -2.57392866456826 0.0105928612670187 -28.9669966996699 36.767743806468 -0.787837210032295 0.431488179316073 PCED1B-AS1 other 1 1 1 -2.57392866456826 -0.787837210032295 0.130975481741126 3.19585217915402 1.69178968857315 1.88903632687901 0.0599506555189657 -0.811086703419119 4.37799316419217 -0.185264497453545 0.85315965339801 NR2F2-AS1 other 1 1 1 1.88903632687901 -0.185264497453545 4.71357084927791e-08 21.2369646333464 6.92646058107033 3.06606301801327 0.00238730889676188 -32.8438339799802 10.9272818235365 -3.00567282059453 0.0028973534438514 TMEM161B-AS1 other 0.000460751550516915 1 1 3.06606301801327 -3.00567282059453 2.99037391766648e-05 3.40774639098055 1.46706664717895 2.32282998017396 0.0209345015261792 -4.29730009489339 2.31659643202364 -1.85500591967135 0.0646894088470992 SEC24B-AS1 other 0.234265892709992 1 1 2.32282998017396 -1.85500591967135 0.416090013510241 -13.0267499923197 14.0983294350865 -0.923992452602223 0.356312227259628 -34.0292974981036 27.3033096375074 -1.24634331697856 0.213714654629822 LINC00926 other 1 1 1 -0.923992452602223 -1.24634331697856 0.019010238643133 24.4620680534397 8.87522409413538 2.75621976346534 0.00624421281286426 4.42917691401887 18.5193064891597 0.239165376771073 0.811158122822517 NRAV other 1 1 1 2.75621976346534 0.239165376771073 3.41746161890634e-05 29.7595469926109 13.195152002246 2.25533946009454 0.0249070232347699 -36.0505521341446 20.4413000979283 -1.76361346692416 0.0789197483770079 FAM13A-AS1 other 0.26601521241567 1 1 2.25533946009454 -1.76361346692416 1.43633058358285e-16 56.0069930748567 11.7473934113207 4.76761023606174 3.05173995327893e-06 -91.7216679864811 22.3799628104855 -4.09838339603975 5.50721193533238e-05 UBA6-AS1 other 1.97423638713462e-12 0.829881766535236 0.0326566692400378 4.76761023606174 -4.09838339603975 1.3465629402013e-16 292.562274497431 38.1264698174498 7.67346874489626 2.97733193476136e-13 -270.38456490471 115.650220469828 -2.33795114100324 0.0201122133938168 BCKDHA other 1.85219732424689e-12 1 4.24418667300231e-09 7.67346874489626 -2.33795114100324 0.0128502160588981 -199.745100655469 668.723041128875 -0.298696303806548 0.765400688592828 -2449.82297372641 987.98766046917 -2.47960887746619 0.0137608844753414 ADH1C other 1 1 1 -0.298696303806548 -2.47960887746619 4.4521828086504e-26 229.931911340096 21.1708826586659 10.8607616908206 4.47513807663887e-23 -51.5010494138015 41.1230241032193 -1.25236532421675 0.211508567817785 TRIM39-RPP21 other 6.86125892641114e-22 1 6.95167948825083e-19 10.8607616908206 -1.25236532421675 0.0106801399809439 44.9405251739358 15.1659356176681 2.96325438185169 0.00414003447726785 51.4293035086407 21.2548662398042 2.41964841972651 0.0180984812232735 TRIM52-AS1 other 1 1 1 2.96325438185169 2.41964841972651 5.8001623179667e-07 67.6312289705162 13.3457278460075 5.06763136120362 7.46581368761084e-07 14.0395928392432 21.4471109868509 0.654614640072072 0.513271084680496 LUCAT1 other 0.00526712740094556 1 0.00834827286548644 5.06763136120362 0.654614640072072 0.156752452455844 -31.7593580414211 37.1371936768209 -0.855190037184842 0.393201375535174 -102.398667628421 53.9446063573423 -1.89821883118596 0.0587296731738987 APELA other 1 1 1 -0.855190037184842 -1.89821883118596 3.07827381795043e-10 214.343448858546 53.1341744106422 4.03400356241566 7.15673360836544e-05 -206.931857900731 84.0792983196488 -2.4611511042115 0.014479811881336 CDK11B other 3.41965438436113e-06 1 0.681893578205059 4.03400356241566 -2.4611511042115 0.332151603309701 -3.35939086294398 22.2445554469868 -0.151020813652585 0.880072066129722 -39.3563089195067 32.4495739776425 -1.21284516544417 0.22624910219446 LINC00504 other 1 1 1 -0.151020813652585 -1.21284516544417 0.00142832818735178 116.852962276248 38.6521931766468 3.02319099312712 0.00273995294811723 -29.5411253010791 67.2926552202127 -0.438994793776629 0.661013826259922 PCDHAC1 other 1 1 1 3.02319099312712 -0.438994793776629 0.248077403067259 8.34845869297155 5.10319441418882 1.63592801202315 0.103011229112825 9.18765160856396 8.40540049407148 1.09306529951122 0.275332259867767 SEMA6A-AS1 other 1 1 1 1.63592801202315 1.09306529951122 0.0107219020039113 -114.431065247704 42.6723630937931 -2.6816200686188 0.007772977409181 -239.382275611055 149.82931142971 -1.59769989814949 0.111266555664247 PCP4L1 other 1 1 1 -2.6816200686188 -1.59769989814949 0.00199065089077928 22.52460783096 25.5835328681561 0.880433830114075 0.379404447571494 -179.474741902723 60.4706866622995 -2.96796269083244 0.0032657158558025 ABHD14A other 1 1 1 0.880433830114075 -2.96796269083244 0.00203769952624893 1.72064462553559 0.484987882756183 3.54780951589383 0.000457374967442176 0.548270036851344 2.03549398482955 0.26935478116741 0.787860895179786 ZFAT-AS1 other 1 1 1 3.54780951589383 0.26935478116741 0.00616985641566489 9.06940975938479 5.4072399038832 1.67727156934014 0.0946339169863488 -14.2773313765554 9.3794735204251 -1.52218899551926 0.129119170921287 SRP14-AS1 other 1 1 1 1.67727156934014 -1.52218899551926 0.00469199273953514 13.5164497453922 4.09395136152902 3.30156578615141 0.0010930463262191 9.66694164852965 27.4409313424843 0.352281835039732 0.724905855462868 GDNF-AS1 other 1 1 1 3.30156578615141 0.352281835039732 0.135210844209772 41.4198318149961 35.3949178871433 1.17021974587039 0.242936845635475 -98.8958234057472 85.004506628756 -1.16341859188313 0.245679292697755 TMEM110-MUSTN1 other 1 1 1 1.17021974587039 -1.16341859188313 0.00669350252265052 14.3554732414148 4.54115183704321 3.16119648858995 0.00174892131611679 3.46378826751409 21.4756355832413 0.161289208605173 0.871985356060939 DSTNP2 other 1 1 1 3.16119648858995 0.161289208605173 1.70786753167795e-09 347.455425957765 73.2280146132989 4.74484291008845 3.36908980003728e-06 -595.860548869137 197.780607344275 -3.01273495349283 0.00283201305302829 RBM14-RBM4 other 1.8221238695472e-05 1 0.0359347118071976 4.74484291008845 -3.01273495349283 9.1409783016881e-23 15.1488130935232 1.35683150341093 11.164844754445 8.50418423537615e-24 12.3716170805052 8.78095598122492 1.4089145996128 0.160088254679981 OXCT1-AS1 other 1.37717979093233e-18 1 1.32418652729042e-19 11.164844754445 1.4089145996128 3.55665724948046e-11 4.74702992255787 0.742042557737367 6.39724753393188 7.27773671677384e-10 -2.13301502996559 1.95209106879582 -1.09268213151622 0.275540920741091 ALG1L9P other 4.12536674367238e-07 1 9.44941335305915e-06 6.39724753393188 -1.09268213151622 0.866276077823815 -31.4752844252648 62.7533502392259 -0.501571379141924 0.616374773674492 -58.6438799529227 164.226385714727 -0.357091704220973 0.721300041197178 LY75-CD302 other 1 1 1 -0.501571379141924 -0.357091704220973 0.0114666744618518 8.64602616078945 4.33364006476927 1.99509558513595 0.0470336929995843 -6.99579467677835 7.78889773334844 -0.898175186820802 0.369889447376208 CCDC153 other 1 1 1 1.99509558513595 -0.898175186820802 2.3912811381267e-08 2.32799734614998 0.463606236055078 5.02149704878734 9.26937900947645e-07 -5.89422144732546 2.27428723302153 -2.59167855394177 0.0100648506506741 NPHP3-AS1 other 0.00023807368255604 1 0.0103066225206369 5.02149704878734 -2.59167855394177 0.1983970934769 0.101433882103033 0.894908085904932 0.113345586771029 0.909839882757642 -4.08638475836429 2.41599095644984 -1.6913907510519 0.0919033557155933 ACTN3 other 1 1 1 0.113345586771029 -1.6913907510519 0.171667121414486 12.2475730231363 7.83600382875053 1.5629871157285 0.119226916586587 -11.0016386365872 25.0408106124179 -0.439348342466654 0.66076056818839 C8orf34-AS1 other 1 1 1 1.5629871157285 -0.439348342466654 5.76583659759168e-12 11.2540173053152 2.17426659127642 5.17600617627503 4.81952684197674e-07 -11.0965475301257 4.40787857721735 -2.51743493740492 0.0124792670047382 USP46-AS1 other 6.89478740340013e-08 1 0.00545377657438088 5.17600617627503 -2.51743493740492 0.164953271057937 -160.201943014235 90.1083992707537 -1.77788024546821 0.0765365950062708 -305.857579269854 262.307407619382 -1.16602722754085 0.244621098358434 TNFSF12-TNFSF13 other 1 1 1 -1.77788024546821 -1.16602722754085 0.219362189487036 5.17692946674277 3.43832376469986 1.50565502873598 0.133364999431741 -15.4264085536483 23.0697419984801 -0.668685785678257 0.504286914616798 C5orf17 other 1 1 1 1.50565502873598 -0.668685785678257 0.0180806503109252 3.81733746130016 13.0077303288333 0.293466835858256 0.769390788507638 -37.4809875367152 19.0234847475216 -1.97024825021075 0.0498316387333253 HHIP-AS1 other 1 1 1 0.293466835858256 -1.97024825021075 0.0632674565095401 -15.5780030467735 25.4538466328661 -0.6120097787758 0.541048221875947 -104.932570386112 46.5716724914662 -2.25314155091467 0.0250559921380339 FMN1 other 1 1 1 -0.6120097787758 -2.25314155091467 7.95508599024696e-19 388.456755990197 40.0988289938904 9.68748379284052 3.18934137710396e-19 -28.4146016114856 184.574178662723 -0.153946786150452 0.877767554217445 ATP5J2-PTCD1 other 1.14258900077917e-14 1 4.86183199525728e-15 9.68748379284052 -0.153946786150452 0.644960737005078 1.00900911496616 11.40928401294 0.0884375490891265 0.929593757653645 -14.2640483891292 18.5584700523324 -0.768600447607292 0.442794917863905 C5orf66-AS1 other 1 1 1 0.0884375490891265 -0.768600447607292 2.89919624853104e-06 34.2587332368285 8.43266059986928 4.06262446248099 6.35350155451911e-05 -2.49646300494359 12.4707294669472 -0.200185804010927 0.841484858490295 ZNF436-AS1 other 0.0248316158686683 1 0.608093633783024 4.06262446248099 -0.200185804010927 0.00451319826941668 -24.462320840381 8.98425772938281 -2.72279820739976 0.00689638454509443 -43.4678677845214 13.6181251260837 -3.19191279137717 0.00158112905235384 LINC02362 other 1 1 1 -2.72279820739976 -3.19191279137717 1.58905547453973e-21 239.346211517536 23.6359985303192 10.126342291421 1.25197202207444e-20 -96.4223471564805 91.9361444595325 -1.04879694187005 0.295212956011604 HAUS5 essential 2.36467345166258e-17 1 1.9222778426931e-16 10.126342291421 -1.04879694187005 1.2344823117919e-06 179.548978912172 36.7948233384727 4.87973477302812 1.81853863991314e-06 28.3993952069488 67.2873641567952 0.422061341870543 0.673316114302118 PCDHA11 other 0.0109165270831758 1 0.0197966116340944 4.87973477302812 0.422061341870543 0.111379830212237 26.9905208307963 16.054319775536 1.68119990184357 0.0938761562031783 -27.3436825829706 33.4858468211218 -0.816574319563661 0.414888956012261 TMEM132D-AS1 other 1 1 1 1.68119990184357 -0.816574319563661 0.0980696995545396 -2.65982700126354 3.96123645733761 -0.671463829516313 0.502499164874094 15.0114648171703 9.00730065871834 1.66658862471083 0.0967558129999964 ATP5L2 other 1 1 1 -0.671463829516313 1.66658862471083 0.000680771042721772 68.6396943143152 73.0575600380057 0.939528972478793 0.34829896809634 -267.506761032548 110.732158185816 -2.41580011999453 0.0163648008608606 TMEM150C other 1 1 1 0.939528972478793 -2.41580011999453 0.139753995061439 14.0694305694305 9.68669391006754 1.45244917409932 0.147525103762816 -20.1972333222334 24.3610074829242 -0.829080379224487 0.407783226336171 APOBEC3B-AS1 other 1 1 1 1.45244917409932 -0.829080379224487 4.82493406480279e-11 13.0132995566815 2.73717820460849 4.75427560206765 3.23798800662887e-06 -5.54939835338821 4.40594449068309 -1.25952525392072 0.208924358177386 UGDH-AS1 other 5.57038637781482e-07 1 0.0345719979467765 4.75427560206765 -1.25952525392072 0.174726404567168 8.62320441759492 16.9598669735403 0.508447644727893 0.61155928679178 -34.4978204843321 26.3171954572727 -1.31084714328094 0.1910357467033 NAIP other 1 1 1 0.508447644727893 -1.31084714328094 7.33406287371467e-11 45.7933829095605 7.22158208634852 6.34118429479976 9.41017653665548e-10 5.64713626621708 18.7628774178959 0.300973893312914 0.763663500227321 ZNF286B other 8.39530177154118e-07 1 1.21701813148565e-05 6.34118429479976 0.300973893312914 5.60262894298911e-16 34.2365694546408 5.63729389488116 6.07322770340724 4.35044425969714e-09 -51.5234509371287 13.7330488843462 -3.7517853006304 0.000215870979067411 ZNF324B other 7.59380326932744e-12 1 5.48417003377422e-05 6.07322770340724 -3.7517853006304 7.49020293367538e-22 21.5493840617123 4.62243215790941 4.66191462103761 4.93712745512501e-06 -31.4227696379331 6.5947169822364 -4.76483975318029 3.09602679410116e-06 MIR302B other 1.11918612234978e-17 0.048109160353538 0.0519682035926459 4.66191462103761 -4.76483975318029 2.01007885518407e-06 137.721471455545 26.8315799889052 5.13281258548666 5.4530762428501e-07 19.6313087383584 57.0744703887853 0.34395954276285 0.731143439861458 LINC01234 other 0.0174695953304048 1 0.00615107000193491 5.13281258548666 0.34395954276285 0.752405458939631 -7.628374575522 11.8272824318508 -0.644981179698462 0.519483010448648 -18.8131194355151 32.4522773927404 -0.579716462047857 0.562585697267608 HOXC13-AS other 1 1 1 -0.644981179698462 -0.579716462047857 0.108014217433842 -17.5946976672063 15.6300147402718 -1.12569936494508 0.261281430545445 -54.7172541456279 25.894463137433 -2.11308702772557 0.0355008632006966 MIR143 other 1 1 1 -1.12569936494508 -2.11308702772557 5.90197475738855e-29 193.624785881216 25.4471208198814 7.60890739866886 4.58249591743824e-13 -131.887884100116 40.0904725468442 -3.28975628675892 0.00113548250436079 NOP14-AS1 other 9.20590022657466e-25 1 6.50760245235404e-09 7.60890739866886 -3.28975628675892 2.80077640010541e-06 42.7925515063565 12.3487449177575 3.46533609620691 0.000622692477133446 -54.9376805447683 27.2764241488788 -2.01410860327256 0.045065052270011 SRD5A3-AS1 other 0.0240138568545038 1 1 3.46533609620691 -2.01410860327256 4.19896595813171e-15 35.9836470096089 6.57932176650635 5.46920310126683 1.03619126838323e-07 -49.0948838881037 14.4160595806219 -3.40556888056269 0.000761471096516767 ZNF564 other 5.56992834346172e-11 1 0.00122394912621427 5.46920310126683 -3.40556888056269 0.0387247771012591 -1.47791128751542 41.2943677192303 -0.0357896577461623 0.97147642752605 -154.004369845035 67.917150580369 -2.26753284743293 0.0241453389976961 ECSCR other 1 1 1 -0.0357896577461623 -2.26753284743293 0.138108367255863 4.77858173495536 2.49495507665157 1.91529770602868 0.0565148134761886 -2.68293840336343 10.9479026320164 -0.245064145484575 0.806593610176396 LINC00964 other 1 1 1 1.91529770602868 -0.245064145484575 0.0307550775342352 -56.7841287458376 51.0843234861574 -1.11157640682517 0.26730187554153 124.23499142367 80.1010937465393 1.5509774662601 0.122069807702294 VCAN-AS1 other 1 1 1 -1.11157640682517 1.5509774662601 0.561139097896767 9.41690021351122 8.79644119954167 1.07053523122531 0.285324004412541 4.73875292350334 16.0345772922296 0.295533386202812 0.767811104071145 HS3ST5 other 1 1 1 1.07053523122531 0.295533386202812 5.61795565712654e-07 161.747914537242 29.9459723743796 5.40132450918929 1.46396816507235e-07 -44.7648949849979 123.853373751387 -0.361434603104598 0.718060427097141 RNF103-CHMP3 other 0.00510728348789374 1 0.0017138675308502 5.40132450918929 -0.361434603104598 1.26698343120976e-23 9.21446941318792 0.817107601692352 11.2769351234811 2.37661610143003e-24 -0.735799533995178 4.70360565963111 -0.156433082881545 0.87581076935618 BRD9P2 other 1.92252065851768e-19 1 3.70609514856999e-20 11.2769351234811 -0.156433082881545 3.09163198062224e-18 600.766644232683 63.3740121597589 9.47970033391947 1.54482265792643e-18 -348.344794040717 364.54422421416 -0.955562510396745 0.340167481731911 PDCD6 other 4.40001063482157e-14 1 2.34380493660598e-14 9.47970033391947 -0.955562510396745 0.0479158992456191 204.065608828811 91.4636523135817 2.23111152536502 0.0264860192495303 423.521065817114 240.350950163327 1.76209441039994 0.0791724691565342 TMEM158 other 1 1 1 2.23111152536502 1.76209441039994 1.69375956252183e-08 199.73065514725 34.9165074380152 5.72023577964713 2.79972287633167e-08 -32.3916641163874 74.4690304346229 -0.434968253612814 0.663930379876667 C15orf38-AP3S2 other 0.000170121210459692 1 0.000340026343330481 5.72023577964713 -0.434968253612814 0.00857089510380466 31.7861764979891 11.5047316833872 2.76287855925299 0.0061231902347052 5.44943946710552 21.9176678777692 0.24863226769819 0.803834257866268 TMPRSS11BNL other 1 1 1 2.76287855925299 0.24863226769819 0.000141185417742516 95.2653127948741 22.4504294330015 4.24336260823754 3.02632583769463e-05 71.0251076625459 33.0960578349174 2.14602923456377 0.032758807684922 SLC7A11-AS1 other 1 1 0.298607570405329 4.24336260823754 2.14602923456377 0.04233536302526 14.4697055783616 5.73372242010145 2.52361459418289 0.0121876208173787 14.0369977401592 33.1400281944674 0.42356625823579 0.672218140824899 LINC01018 other 1 1 1 2.52361459418289 0.42356625823579 0.0380049916521904 31.8429528534287 13.4495916867815 2.36757766295052 0.0186101407519921 4.47714022505333 30.949597544682 0.14465907734631 0.88508797209732 YJEFN3 other 1 1 1 2.36757766295052 0.14465907734631 2.35154583809475e-05 182.085307781567 42.9416117377825 4.24029980275187 3.07929165501624e-05 25.0043172752676 77.1042205861728 0.324292458767837 0.745970535630042 PCDHA10 other 0.186265945835485 1 0.303494985518401 4.24029980275187 0.324292458767837 0.000976332851734319 10.0014580508202 2.85049076407695 3.50867933931331 0.000526797703531114 -1.33883967862445 7.82131630949769 -0.171178306265233 0.864210837484481 HOXC-AS2 other 1 1 1 3.50867933931331 -0.171178306265233 0.182454618151594 54.8735927034347 31.9734664707344 1.7162228172432 0.0872640257402377 -17.0749608094627 66.6407702745609 -0.256223941276694 0.797972314967942 FZD10-AS1 other 1 1 1 1.7162228172432 -0.256223941276694 0.163473148796326 5.42869972877337 3.20495946469943 1.69384349117891 0.0914568391338654 -3.09298942036535 10.6281969652608 -0.291017322173748 0.771263164788134 RDH10-AS1 other 1 1 1 1.69384349117891 -0.291017322173748 0.0208877150828518 -10.184961904013 17.3672585234466 -0.586446150396323 0.558065703800431 -72.8479597046569 28.7355514959862 -2.5351161161752 0.0118058900176024 KIAA1456 other 1 1 1 -0.586446150396323 -2.5351161161752 2.77715832694584e-07 18.4732057488883 11.1672155208829 1.65423562519619 0.0992771441726004 -54.7245815058202 17.5297396923942 -3.12181369866913 0.00199878843367949 ZNF718 other 0.00258330444975871 1 1 1.65423562519619 -3.12181369866913 1.04998288110959e-13 39.0073330817439 23.960589547583 1.62797885270226 0.104708764868649 -171.64362258678 34.5153670366329 -4.97296240264824 1.18139810134879e-06 SMIM20 other 1.3374681939574e-09 0.018473522110791 1 1.62797885270226 -4.97296240264824 4.24018122050806e-09 202.376636542547 34.5703788924034 5.85404739625281 1.38299892876765e-08 -39.6829375467417 96.8535808518626 -0.409720912719135 0.682334363260841 CHCHD10 other 4.41318061430479e-05 1 0.000170592917863489 5.85404739625281 -0.409720912719135 0.00312352992902439 9.86833298538487 4.35117886910548 2.26796766629215 0.0241184541148466 -4.39572110955124 6.32041918209837 -0.695479363457641 0.487350880670964 FAM218A other 1 1 1 2.26796766629215 -0.695479363457641 0.249876244127251 21.0532856843619 12.9018197759487 1.63180745429486 0.103881507715105 0.539069109139445 29.6304033206547 0.0181931073737248 0.985498188398267 CDK3 other 1 1 1 1.63180745429486 0.0181931073737248 0.951861711254785 1.81216496354268 5.8086996481173 0.311974292581995 0.755299070372777 2.64123356746891 27.4700167120358 0.0961496891376725 0.923472489978537 GPR162 other 1 1 1 0.311974292581995 0.0961496891376725 4.40360822994852e-09 84.1934703510989 13.1095217822281 6.4223143871835 6.05489907972592e-10 60.6618156136093 52.6865992457517 1.151370870051 0.250602028101015 ATP6V1E2 other 4.58019291996945e-05 1 7.8822676219872e-06 6.4223143871835 1.151370870051 4.6247831489578e-08 74.1347149491049 13.4689307111942 5.50412772466714 8.62479188682322e-08 -45.0032177335021 50.249848607932 -0.895589120767984 0.37126998311284 GLI4 other 0.000452257544136583 1 0.00102307281361497 5.50412772466714 -0.895589120767984 0.0203995368813535 37.4886204031156 14.960420829956 2.50585333321975 0.0128022260832967 5.0565552465473 22.875221953908 0.221049450656082 0.825220385334737 CCDC169-SOHLH2 other 1 1 1 2.50585333321975 0.221049450656082 0.000332561937550518 948.356016510184 355.433943259661 2.66816390075994 0.00812742027683381 -5829.36679154709 2254.44178274942 -2.58572513876932 0.0102865876876449 SELENOP other 1 1 1 2.66816390075994 -2.58572513876932 3.60980686431409e-13 18.1811825613359 2.54506811438757 7.14369193443411 8.58223794695049e-12 -16.5010307872878 8.32703329442379 -1.98162180981524 0.0485432850680192 NT5C1B-RDH14 other 4.51875623274838e-09 1 1.18314732336659e-07 7.14369193443411 -1.98162180981524 0.151698820908031 23.248880964882 14.9909078748604 1.55086544183693 0.122096656263259 -25.2535459720402 41.1327879863488 -0.613951720958506 0.539760365844107 LINC02381 other 1 1 1 1.55086544183693 -0.613951720958506 2.12852692886551e-07 58.2745447991489 11.1577772092995 5.2227736498072 3.52543907350078e-07 -130.930997752654 70.0393768051455 -1.86939124425555 0.062650793619218 SNHG18 other 0.00199655825927585 1 0.00403380738789959 5.2227736498072 -1.86939124425555 4.45901534127613e-10 31.4828268973377 9.39752839957872 3.35011777125877 0.000923430452558404 -31.9444238576152 13.5339075929261 -2.36032525257612 0.0189729543920552 SMAD1-AS1 other 4.91205129994979e-06 1 1 3.35011777125877 -2.36032525257612 4.1299471817764e-12 5.09092322205783 2.05835365498336 2.47329860431539 0.0140052846205314 -13.6543759782166 3.22460872050481 -4.23442878244125 3.14842898985331e-05 GLUD1P3 other 4.96791346495884e-08 0.478088942109226 1 2.47329860431539 -4.23442878244125 1.54616310324352e-09 29.8491645710131 5.39610321096002 5.53161483464337 7.4943243154361e-08 -15.4661127974341 10.5093504650114 -1.47165258680117 0.142279290877518 SNHG21 other 1.65362143891895e-05 1 0.000891824593536895 5.53161483464337 -1.47165258680117 6.67590754538715e-12 190.973011017539 54.1800196258782 3.52478667110566 0.000497962872329089 -258.890346252841 82.2462861498075 -3.14774512470125 0.00183052208955221 THAP9-AS1 other 7.96702806466502e-08 1 1 3.52478667110566 -3.14774512470125 0.0195871239693974 12.8427760381057 4.65661349748047 2.75796478386159 0.00621042129063678 4.02415529374432 12.7770444141975 0.314951968803738 0.753039598465225 HOXC-AS3 other 1 1 1 2.75796478386159 0.314951968803738 6.95619517745816e-06 83.4963848396497 28.1372198854393 2.96747102875143 0.00326876828655487 -98.1689706212165 46.0234288398948 -2.13302166083115 0.0338148897822904 TMED7-TICAM2 other 0.057694682801838 1 1 2.96747102875143 -2.13302166083115 1.36189076624865e-06 17.3544823784104 3.43095676890646 5.05820491114546 7.8275786014387e-07 -6.51698800511478 15.0327146893775 -0.43352036806232 0.66498292969796 ZNF345 other 0.0120009814321831 1 0.00874340529780703 5.05820491114546 -0.43352036806232 0.742563117270265 -2.50352511105434 6.31682965558092 -0.396326202787893 0.692177434293409 -19.5301128258293 26.7014145906851 -0.731426148210233 0.465153212837479 LINC02384 other 1 1 1 -0.396326202787893 -0.731426148210233 0.0438879113868329 49.5593218961441 41.7463265641529 1.18715407977238 0.236250348148317 -128.991051629901 87.0144345019595 -1.48240981359243 0.139442308720575 SHANK3 other 1 1 1 1.18715407977238 -1.48240981359243 1.67642466015295e-08 41.6648086213305 12.8851638980889 3.23354898322327 0.00137403407841139 -99.1528196356568 28.5908733914818 -3.46798848282816 0.000609709883463324 ZNF550 other 0.000168413621358965 1 1 3.23354898322327 -3.46798848282816 0.144713129998597 -6.92970890914438 3.5199798159644 -1.96867859233612 0.0500015054173123 -4.88550846389718 5.7256388678992 -0.853268705312133 0.394258329891047 DCANP1 other 1 1 1 -1.96867859233612 -0.853268705312133 0.0595337820357343 101.551472604222 62.3870955131038 1.62776407154413 0.104758778483625 -46.7459751703972 98.0765096957848 -0.476627638110232 0.634018595028536 LINC00958 other 1 1 1 1.62776407154413 -0.476627638110232 6.39712595021496e-09 57.5981494217271 9.76487712424648 5.89850222269661 1.08602390503987e-08 -49.0435675999181 37.311186673089 -1.31444673763998 0.189803209658593 RPL32P3 other 6.59671627986167e-05 1 0.000134634383507793 5.89850222269661 -1.31444673763998 0.110771589949711 30.6691795292594 23.8855078316021 1.28400784883803 0.200231854345223 77.5596870503992 37.1853637957141 2.08575845799144 0.0379324472376775 FOXD1 other 1 1 1 1.28400784883803 2.08575845799144 0.400453885885616 434.735927691217 384.507026585302 1.13063194592823 0.259224618119374 -309.799706193593 915.390990383894 -0.338434296872061 0.735301908452276 MALAT1 other 1 1 1 1.13063194592823 -0.338434296872061 1.12229596826761e-45 90.918199285521 5.42038973328873 16.7733693994653 1.94970858704156e-43 26.7103649250652 14.8412201878531 1.79974183975294 0.0730474409057025 ABCA11P other 1.78534842632011e-41 1 3.10101150768961e-39 16.7733693994653 1.79974183975294 2.74854558471776e-06 169.531228102895 36.2350076377695 4.67865854473241 4.57122451651244e-06 19.5040150798622 66.2636189802688 0.294339720347449 0.768724486302066 PCDHA12 other 0.0235825211168784 1 0.0482264186492062 4.67865854473241 0.294339720347449 3.47394636660899e-10 30.0145556785806 5.70015323119897 5.26556996999665 2.83501645075016e-07 -0.860369676913748 9.06601699370087 -0.0949005144719604 0.924463466127064 FAM86EP other 3.84843778492944e-06 1 0.00326140292494298 5.26556996999665 -0.0949005144719604 0.00138865761383639 191.285422384264 179.394952108097 1.06628096351899 0.287242184509427 -806.460472632328 303.534849551474 -2.65689581879647 0.00835256300530764 PCDHGA12 other 1 1 1 1.06628096351899 -2.65689581879647 0.000312435242658346 40.672558739708 11.2908893487179 3.60224580044499 0.000375202344635935 -21.8320286479888 31.2070187784826 -0.699587128234179 0.48478523612547 HOXA10-AS other 1 1 1 3.60224580044499 -0.699587128234179 0.153549950329437 2.46825217172802 1.94524252845215 1.26886603373412 0.205593902638849 5.75792319881051 3.01849819417471 1.90754568279104 0.0575228203107521 GUSBP3 other 1 1 1 1.26886603373412 1.90754568279104 0.0751249159427554 10.2053180164246 4.88144728701334 2.09063366177793 0.0374995162757043 -5.46073094210815 17.0002186911148 -0.321215335009908 0.748296639887557 C8orf88 other 1 1 1 2.09063366177793 -0.321215335009908 0.0116624116805527 34.4930411082809 26.9877819414509 1.27809840701664 0.202312408259525 -218.687996711547 95.9068895883542 -2.28021154319764 0.0233749456559325 CCDC71L other 1 1 1 1.27809840701664 -2.28021154319764 4.66376605400549e-05 80.8881020923801 20.7673737896904 3.89496057188201 0.000123779823158061 -58.8910047075477 57.3991829889141 -1.02599029534831 0.305811074333124 HOXA10 other 0.358037319966001 1 1 3.89496057188201 -1.02599029534831 0.0106088155632366 61.4556948915326 24.5146942258854 2.50689216537895 0.0127655333008973 -1.55536738978297 35.6297885107934 -0.0436535678372551 0.965212698518206 TMEM200B other 1 1 1 2.50689216537895 -0.0436535678372551 0.00123716140201352 194.142010056293 178.308106792434 1.08880080411762 0.277205484180365 -805.92450881539 301.695915816166 -2.67131395078768 0.00801101617277672 PCDHGB6 other 1 1 1 1.08880080411762 -2.67131395078768 2.20116035465779e-08 6.73017923680791 1.97514217852773 3.40744039086065 0.00075493961168456 -9.1808449307711 3.23443313896841 -2.83847108173621 0.00487469195239648 SERPINE3 other 0.000219565745377114 1 1 3.40744039086065 -2.83847108173621 2.95311908456847e-06 59.8023468209368 17.0647520145471 3.50443691006804 0.000535492272114263 -53.6659901479445 31.9287512158912 -1.6808045446273 0.0939573082095788 C1orf210 other 0.0252698400066524 1 1 3.50443691006804 -1.6808045446273 4.16421190006605e-09 6.92820392430565 1.09045398229318 6.35350417056199 8.86100991619083e-10 -0.316230509334897 4.30442219214156 -0.0734664248112622 0.941489156489653 RAD21-AS1 other 4.33619385153878e-05 1 1.14696912355174e-05 6.35350417056199 -0.0734664248112622 0.332788183209855 35.2321878176107 30.3718631792878 1.16002721366259 0.247058683614202 -3.87667178693516 43.7790065934918 -0.0885509308818229 0.92950420828889 TRNP1 other 1 1 1 1.16002721366259 -0.0885509308818229 0.0117266249617958 15.3505376132138 11.2933909007123 1.35924964859276 0.175189242655148 -30.6551752458112 18.3164679473415 -1.67364009993316 0.0953466896120184 LINC02159 other 1 1 1 1.35924964859276 -1.67364009993316 0.0471809801457844 4.46778777274118 1.93056402321721 2.31423963101508 0.0214225162606072 -4.9747859534129 8.45152738241174 -0.588625668274565 0.556615679877055 PCAT1 other 1 1 1 2.31423963101508 -0.588625668274565 0.00112803811764723 197.697743678094 177.642507233369 1.11289660767048 0.266735403838232 -804.982753542216 300.569726591508 -2.67818972546173 0.00785260945482553 PCDHGA5 other 1 1 1 1.11289660767048 -2.67818972546173 0.269707750330297 51.0526799360682 32.6911314801081 1.56166757235469 0.119550783712911 60.3481871099225 70.7920446798862 0.852471310622688 0.39471657439677 NACA2 other 1 1 1 1.56166757235469 0.852471310622688 0.000959122298675496 200.875645211913 179.090832532862 1.12164113802449 0.263004269462974 -822.496752145881 303.02028161949 -2.71432904672272 0.0070654857600489 PCDHGA7 other 1 1 1 1.12164113802449 -2.71432904672272 0.0977592903160127 -18.2048612009045 12.413494537754 -1.46653797973945 0.143719581802315 -48.6543283307615 22.7961465302088 -2.13432249464997 0.0337592676653485 NKX2-1-AS1 other 1 1 1 -1.46653797973945 -2.13432249464997 1.45236512985146e-06 5.51780851125692 1.14605649787737 4.81460427254375 2.44621505699782e-06 0.525581260115698 1.89868776394929 0.276812896830642 0.782133245776614 GRPEL2-AS1 other 0.0127648371262645 1 0.0263677520993795 4.81460427254375 0.276812896830642 0.0522235494226633 326.158140933544 143.42332166574 2.27409417900446 0.023745327376659 457.747356521545 218.396394729923 2.09594740374543 0.0370178714330314 EIF5AL1 other 1 1 1 2.27409417900446 2.09594740374543 0.00202826539386048 10.495503974237 5.29513124889494 1.98210459399422 0.0484738651521494 -14.0582834753047 8.58125224786338 -1.63825547475371 0.102524627620609 LINC01484 other 1 1 1 1.98210459399422 -1.63825547475371 9.82299833555383e-17 87.9950647052555 13.2940205423287 6.6191461360448 1.91735224773524e-10 -53.7936283269676 21.7164605588094 -2.47709004795194 0.0138539010501689 ALG11 other 1.35547554032307e-12 1 2.54106693392351e-06 6.6191461360448 -2.47709004795194 5.2304676690995e-05 20.131600730113 4.92497722786214 4.08765356644132 5.75820504896087e-05 -14.9924597863595 18.607899882774 -0.80570402252855 0.421125169887972 MINCR other 0.399869253302657 1 0.553478669306119 4.08765356644132 -0.80570402252855 3.0183157375725e-08 525.682604329738 135.314177623648 3.88490410658838 0.000128944881235355 -1073.30859835468 335.08067178387 -3.2031349126785 0.0015229810056088 ATXN7L3B other 0.000298873624334429 1 1 3.88490410658838 -3.2031349126785 2.65537621980401e-07 1984.61741615019 406.456157866231 4.88273428201658 2.01081484260338e-06 -1851.1186164089 1393.08783233227 -1.32878815925756 0.185294420366153 PRKDC ts 0.00247374848636942 1 0.0218258441227947 4.88273428201658 -1.32878815925756 0.00085189834648818 200.274397857866 178.783778911421 1.12020452346011 0.263614747543749 -830.706710797414 302.500749304378 -2.74613108465908 0.00643253303271019 PCDHGA6 other 1 1 1 1.12020452346011 -2.74613108465908 1.72781940577003e-17 114.074233051515 13.2148332146362 8.63228700648083 5.36602121571571e-16 -62.7111523307686 46.0222227971403 -1.36262762898678 0.174139576623274 OTUD6B-AS1 other 2.42499453599824e-13 1 7.94922382896125e-12 8.63228700648083 -1.36262762898678 0.00106452991515875 200.710758094783 177.086221307462 1.13340697324104 0.258041394141652 -802.536474273505 299.628495175329 -2.67843842356815 0.00784693309319711 PCDHGA8 other 1 1 1 1.13340697324104 -2.67843842356815 2.1026178103129e-16 180.865315287628 29.7289743272399 6.08380609760579 3.96918076934307e-09 -148.283886025819 48.5637957588315 -3.05338336324036 0.00248699018611714 UTP14C other 2.87932482944248e-12 1 5.0154568201419e-05 6.08380609760579 -3.05338336324036 0.00205570462858493 183.175464252091 187.567276148236 0.976585404520804 0.329642194277228 -829.908903534834 317.362357621572 -2.61501997197926 0.00942004218163418 PCDHGA10 other 1 1 1 0.976585404520804 -2.61501997197926 0.00124886720946365 188.497712961666 177.841125793943 1.05992195067451 0.290120393101873 -809.329465586099 300.905787635553 -2.68964406416248 0.00759497588110126 PCDHGA11 other 1 1 1 1.05992195067451 -2.68964406416248 0.431008793777593 42.8792574352927 34.3787289505365 1.24726127882699 0.213382493054132 8.83350071098896 111.272587826061 0.0793861352878509 0.936784301777566 LINC01419 other 1 1 1 1.24726127882699 0.0793861352878509 0.00108940644252621 215.102412575041 180.875190148324 1.1892311620994 0.235385834060068 -805.171411761124 306.039400686056 -2.63094036243749 0.00900057334494651 PCDHGB2 other 1 1 1 1.1892311620994 -2.63094036243749 0.00103607237211122 210.17514373285 178.390108945703 1.17817711405076 0.23975573263757 -800.604063026543 301.834662815248 -2.65245898386625 0.00846027051644773 PCDHGB4 other 1 1 1 1.17817711405076 -2.65245898386625 9.19180265992443e-07 46.784425013468 17.569465402295 2.66282575720015 0.00821751540639378 -62.9422424820082 29.5779152696869 -2.12801483499126 0.0342484997867546 CLDN23 other 0.00820276469371656 1 1 2.66282575720015 -2.12801483499126 5.39627660619706e-14 128.976877957339 16.9291783512619 7.6186141631454 4.38762169066666e-13 -95.2275544603846 69.5735876468066 -1.368731406289 0.172225162942198 ZNF260 other 6.93691357726632e-10 1 6.23305537376105e-09 7.6186141631454 -1.368731406289 0.328435304805452 117.5991401948 117.011987478617 1.00501788516574 0.315826253982339 -257.273642752286 364.399983183978 -0.706019908410352 0.480810331817579 LYN other 1 1 1 1.00501788516574 -0.706019908410352 3.88098834422369e-31 108.928338080432 11.7401459304039 9.27827803216109 5.6970514168583e-18 -47.4185607667457 20.7698644669941 -2.28304622989234 0.02320215055967 PINX1 other 6.09392789810003e-27 1 8.60482646002277e-14 9.27827803216109 -2.28304622989234 0.00203087784780231 0.716404129711021 5.06392528853873 0.141472097017796 0.887602110145153 -23.7165440250692 8.81028461923765 -2.69191576095999 0.00754644224061177 RBPMS-AS1 other 1 1 1 0.141472097017796 -2.69191576095999 0.00228195362127256 193.320218754383 186.687532496933 1.0355282764132 0.301342018817237 -803.638053646906 315.873838275268 -2.54417414887832 0.0115070613539924 PCDHGB7 other 1 1 1 1.0355282764132 -2.54417414887832 0.046756248187747 37.8529135445153 29.5851032378996 1.27945855859054 0.201863214890302 -72.2521119504202 58.9831097455908 -1.22496274377635 0.221685228863314 NPIPB11 other 1 1 1 1.27945855859054 -1.22496274377635 0.0011754365019269 204.779279191576 177.554677191186 1.15333080733815 0.249787099266308 -799.02124695228 306.583074542704 -2.60621447594291 0.00965950443732377 PCDHGB1 other 1 1 1 1.15333080733815 -2.60621447594291 0.00128861141478466 157.767648643213 175.853838309368 0.89715214726029 0.370431112083 -839.79635434808 303.646241664299 -2.76570640145294 0.00606889690215043 PCDHGA3 other 1 1 1 0.89715214726029 -2.76570640145294 0.0581145903780979 32.2106033939266 13.5209613779115 2.38227168125392 0.0178962638303411 18.0744355130587 37.8241872330215 0.477853903421861 0.63313940265328 HOXA-AS3 other 1 1 1 2.38227168125392 0.477853903421861 0.00280054273719423 9.87950557616839 2.94824251799586 3.35098131034492 0.000920671777714984 0.16354957666909 11.0968946377812 0.014738319323341 0.988251873240148 RHPN1-AS1 other 1 1 1 3.35098131034492 0.014738319323341 8.90496959991713e-06 28.5187095457792 8.43900116642483 3.37939395710039 0.000836200239703771 -81.0044861826604 31.6059206559155 -2.56295290570816 0.0109335449032422 LRRC24 other 0.073287899807318 1 1 3.37939395710039 -2.56295290570816 0.00727739391042851 42.4534498676123 80.9804852007535 0.524242967455292 0.600552781935708 -440.744000794551 171.009236480454 -2.57731108486018 0.0105046749932029 CHKB-CPT1B other 1 1 1 0.524242967455292 -2.57731108486018 0.811505570260621 -1.92566556068181 7.88329297406569 -0.244271723379662 0.807203864392628 -11.789410559675 18.2339197328692 -0.646564794207298 0.518456845600732 SIGLEC14 other 1 1 1 -0.244271723379662 -0.646564794207298 0.148648939664758 -7.79809867361281 4.29666623448754 -1.81491841535671 0.070675522680933 -11.57765962916 6.98906448277681 -1.65653924894968 0.098805162513402 SPON1-AS1 other 1 1 1 -1.81491841535671 -1.65653924894968 0.000118508820237362 21.0916218908102 7.20679204348086 2.92663112291263 0.00371491443402485 -15.5086707971121 13.8738886419072 -1.11783157537152 0.264621655259641 NAV2-AS2 other 0.869854740542238 1 1 2.92663112291263 -1.11783157537152 0.00889021626154296 87.9698527444429 35.0425238746492 2.51037434001958 0.0126389119710384 -84.9794080049152 85.6526142238421 -0.992140272366147 0.322007648179288 AP5B1 other 1 1 1 2.51037434001958 -0.992140272366147 5.26962042802381e-20 171.425877126938 34.9561201401174 4.90403043701068 1.61741951639924e-06 -342.698090147067 68.504722772747 -5.00254692342761 1.01647681888879e-06 CHMP4A other 7.70313114168521e-16 0.0159159940301606 0.0176776929788762 4.90403043701068 -5.00254692342761 0.873192219986178 3.44146103624956 6.78204626696957 0.507436974149 0.612257926099372 1.30993166667487 14.8825969328813 0.0880176808242873 0.929927152542943 SIGLEC12 other 1 1 1 0.507436974149 0.0880176808242873 0.00136220128943628 25.195244122099 9.72502074207416 2.59076507807277 0.0101006540513788 -4.9874239276584 13.6427559110777 -0.365573052846947 0.714972055409423 PABPC4L other 1 1 1 2.59076507807277 -0.365573052846947 1.91629092113425e-06 45.4726290295866 11.1534999317354 4.07698294776529 6.02458738573171e-05 -21.865291723931 21.3861547708753 -1.02240407208257 0.30751514070915 BBOX1-AS1 other 0.0166908939230793 1 0.577938667913243 4.07698294776529 -1.02240407208257 0.462002063857163 -1.08036568029557 4.39902276621128 -0.245592200293623 0.80618659966768 -10.8707498141164 9.1440521959769 -1.1888328698407 0.235561693632263 MAGEL2 other 1 1 1 -0.245592200293623 -1.1888328698407 0.0244360098906592 153.479801837731 67.6306627282375 2.26938189936809 0.0240400341963793 4.59170334282245 107.239486264148 0.0428172821670589 0.965879070355037 CSNK2A3 other 1 1 1 2.26938189936809 0.0428172821670589 9.95887514220199e-07 32.1513861213606 8.14294271503588 3.94837434653609 0.000101077691317863 -20.311251432771 16.2343893124477 -1.25112506801825 0.212000633250853 SMG1P6 other 0.00886837831413087 1 0.947805511487605 3.94837434653609 -1.25112506801825 0.751661563290188 -5.27714378871864 18.0465118220078 -0.292419047002931 0.770190827281413 -30.0260110067088 39.787210932837 -0.754664886096046 0.451107804722522 RTL1 other 1 1 1 -0.292419047002931 -0.754664886096046 4.73923246101558e-08 67.1101309627198 25.8408512015785 2.59705574089681 0.00991434837519853 -144.261205542483 44.8213792059814 -3.21858024224368 0.00144438593009954 FPGT other 0.000462975619116612 1 1 2.59705574089681 -3.21858024224368 0.00832565044937702 -4605.27661670429 1475.78716925856 -3.12055607518122 0.00199939667166454 -4950.25988989229 5031.77272176162 -0.983800374862561 0.326087951960256 IGLL5 other 1 1 1 -3.12055607518122 -0.983800374862561 0.0112296805065371 249.510041440867 88.603964597237 2.8160144139718 0.00521954540122224 -247.35041440867 292.006221106457 -0.847072413291132 0.39770219361496 MEX3A other 1 1 1 2.8160144139718 -0.847072413291132 1.77837493842174e-05 2938.19839186435 768.913953520397 3.82123172353954 0.00016524267081481 -2329.31120679536 1570.22967124498 -1.48342070555102 0.139142112645342 EEF1G essential 0.14260788631204 1 1 3.82123172353954 -1.48342070555102 0.000603602459040999 54.6548461304924 25.5928892277166 2.13554810651477 0.0336062111756458 -68.566296806106 44.7154024200525 -1.53339326261677 0.126337015797296 CKLF-CMTM1 other 1 1 1 2.13554810651477 -1.53339326261677 1.84037379587076e-06 115.282806830706 32.6098858197985 3.53521037969148 0.000478731261620094 -310.838484844732 111.392841457284 -2.79047092055669 0.0056355773092074 SYS1-DBNDD2 other 0.0160591017427683 1 1 3.53521037969148 -2.79047092055669 0.025575486167489 -8.31830357503045 6.96567700406447 -1.19418450929848 0.233446173003985 -26.4197803291298 10.0866093341094 -2.61929251485801 0.00930578174712826 SLC22A18AS other 1 1 1 -1.19418450929848 -2.61929251485801 0.125231830517129 -29.9777455749923 20.9842236594847 -1.42858492462944 0.154266671381208 -64.7804530091856 31.850856263006 -2.03386849239675 0.0429316616567335 GVINP1 other 1 1 1 -1.42858492462944 -2.03386849239675 1.24103359384261e-05 29.1096954602663 7.21221802452202 4.0361640983802 7.0747875607405e-05 -3.34012254858509 14.0794037135346 -0.237234659687627 0.812653990080251 NPIPA2 other 0.100821569163774 1 0.674510246041 4.0361640983802 -0.237234659687627 1.86811803604094e-18 85.837451529616 13.3176245016245 6.44540259557142 5.20072422947079e-10 -110.713029654401 30.5070126075776 -3.62910098994422 0.000339450500960485 MPV17L2 other 2.66991429710971e-14 1 6.78694511945938e-06 6.44540259557142 -3.62910098994422 1.65099174349788e-06 8.80439488607421 2.92358713504601 3.01150418283519 0.00284406015314442 -7.56003599443105 4.55231738102987 -1.66070055351034 0.0979258511764244 TMEM9B-AS1 other 0.0144511307308369 1 1 3.01150418283519 -1.66070055351034 1.04839141552564e-14 956.582540080775 143.969660649809 6.64433420043658 1.64612216543104e-10 -626.537888637516 277.198943564244 -2.26024630751275 0.0245939269925225 ATP6V1G2-DDX39B other 1.37465082403722e-10 1 2.18670868455859e-06 6.64433420043658 -2.26024630751275 8.96338443468803e-15 120.389705882354 15.5145850606903 7.75977606951203 1.7247977757861e-13 9.69656862745104 35.7310782054989 0.27137632320199 0.786307455269224 BORCS8 other 1.17689237627454e-10 1 2.46628833959654e-09 7.75977606951203 0.27137632320199 0.209976488441054 28.1271335959585 27.1972925325491 1.03418873633457 0.301963182326238 -77.1442531761345 74.5458009621966 -1.0348571238138 0.301651454023699 INMT-MINDY4 other 1 1 1 1.03418873633457 -1.0348571238138 5.22211645809568e-15 429.513358264906 63.5842669089817 6.75502571854351 8.64132707960164e-11 -548.322622842866 171.569153321768 -3.19592777738152 0.00155820038927171 DPP3 other 6.91042670899801e-11 1 1.15707369595866e-06 6.75502571854351 -3.19592777738152 6.82361817963344e-09 268.015461198959 50.4949176725091 5.30777103028874 2.30578595754071e-07 -294.56679589552 151.97637026597 -1.93824076321869 0.0536284917422838 STX16-NPEPL1 other 7.02286783047874e-05 1 0.00266733319568309 5.30777103028874 -1.93824076321869 1.09291268844158e-14 566.493822993314 111.589063753461 5.07660700733987 7.16654025600272e-07 -655.183971286482 183.348914167563 -3.57342705988271 0.000417181584483841 ANKHD1-EIF4EBP3 other 1.43237136947153e-10 1 0.00802294181659505 5.07660700733987 -3.57342705988271 4.77390346796733e-24 858.597014691026 88.9285912990074 9.6549040319793 3.64704991454321e-19 -718.815241265364 247.416410053438 -2.90528522788812 0.00396963452149888 BRK1 other 7.26874542032705e-20 1 5.55664524979804e-15 9.6549040319793 -2.90528522788812 0.474704431930116 -61.6744115228467 50.9847619123128 -1.20966361731607 0.227458293121561 -79.2344407335217 97.3051424677256 -0.814288317390855 0.416192119795928 SAA2-SAA4 other 1 1 1 -1.20966361731607 -0.814288317390855 5.45001599677693e-13 78.1785788274286 17.6556546234665 4.42796262697163 1.37908874528332e-05 -65.7140704747918 27.3512980011312 -2.40259421955309 0.0169495747849806 PIGY other 6.78199990638921e-09 1 0.139949925871351 4.42796262697163 -2.40259421955309 0.138953136485653 7.00690665856041 4.30557651505966 1.62740265654373 0.10482668367787 -2.23383523754277 8.83059747557634 -0.252965356389657 0.800488910025179 GRM5-AS1 other 1 1 1 1.62740265654373 -0.252965356389657 9.99920955168473e-14 753.998987242076 108.771594713432 6.9319475293945 3.33975736561204e-11 -325.663821924241 244.556046802485 -1.3316531166668 0.184154065295945 CHMP1B other 1.27439925736222e-09 1 4.52603918187744e-07 6.9319475293945 -1.3316531166668 0.0757799685416711 24.4768274557491 12.9302728808194 1.89298614819319 0.0594172944857582 -17.2786597580821 27.8866246789701 -0.619603840801582 0.536035406676144 EID3 other 1 1 1 1.89298614819319 -0.619603840801582 4.6761056475256e-06 114.052853084924 24.6669904870467 4.62370361495118 5.83218329790441e-06 -0.68646351142501 46.751709100654 -0.0146831746823862 0.988295706662421 MSH5-SAPCD1 other 0.0394055422916982 1 0.0610104694793781 4.62370361495118 -0.0146831746823862 0.00380263367043797 6.24274305022263 3.76665137926339 1.65737213817846 0.0985929342822568 -5.79598168516928 5.6700707754742 -1.02220623245828 0.307588256736104 TOLLIP-AS1 other 1 1 1 1.65737213817846 -1.02220623245828 5.01332611054463e-16 72.7971452176537 9.49668905056543 7.66552898910799 3.13286016482177e-13 -44.5190858444328 22.6255102158304 -1.96765002953542 0.0501204839601692 HTD2 other 6.80408619723118e-12 1 4.46369916283806e-09 7.66552898910799 -1.96765002953542 0.0152793566098419 16.9398234284547 11.4860480336485 1.47481739400961 0.141413927839863 -28.0666039471231 20.7579361931005 -1.35209028903615 0.177465469659048 PDXDC2P other 1 1 1 1.47481739400961 -1.35209028903615 1.31431904951646e-05 18.3146532294225 5.51846515429462 3.31879475856969 0.00102838002982778 -10.2899316503652 10.1123096668685 -1.01756492723701 0.309795695634474 SNHG9 other 0.106551845344299 1 1 3.31879475856969 -1.01756492723701 0.122895780798875 6.22449346145611 3.32435138311369 1.87239336162655 0.0622289851445805 -1.90784210780825 7.74021814595713 -0.246484281428781 0.805493970810615 PGAM1P8 other 1 1 1 1.87239336162655 -0.246484281428781 0.213875649939726 69.0591180661718 47.8212670623741 1.44410891447307 0.149854981524295 -9.10860295176605 85.7886369888906 -0.10617493495025 0.91552153311107 FXYD6-FXYD2 other 1 1 1 1.44410891447307 -0.10617493495025 0.411879441128178 32.6325464672639 26.0321574785251 1.25354752076095 0.211078968140823 47.8659156754331 47.2242323327858 1.01358801003107 0.311676850803051 MIR100HG other 1 1 1 1.25354752076095 1.01358801003107 0.279968680311953 58.736944789211 79.4257568251365 0.739520114596152 0.460231329233835 -185.860058629901 173.719049564528 -1.06988876059251 0.285621368863154 WTAPP1 other 1 1 1 0.739520114596152 -1.06988876059251 2.21085259239806e-07 525.983447921511 145.914192922537 3.60474493526991 0.000371775123480743 -677.485137689314 278.857239316859 -2.42950528861653 0.0157695415046828 EID1 other 0.0020704828280332 1 1 3.60474493526991 -2.42950528861653 0.666530775247135 3.94413267862516 5.70162227660155 0.691756220823534 0.489684842308019 -2.78314460366768 10.9462220990415 -0.254256178842872 0.799491179600612 NOX5 other 1 1 1 0.691756220823534 -0.254256178842872 0.121964552446624 96.3447179440205 49.1616427168417 1.95975383692813 0.0510418436638731 -4.92734114538763 101.969190317344 -0.0483218620257058 0.961495063412905 HCAR3 other 1 1 1 1.95975383692813 -0.0483218620257058 0.878186789653315 -6.44966732609203 14.0391045519335 -0.459407314920505 0.646309996960063 -10.0889243057471 29.8631112057403 -0.337839022740799 0.735746050850715 TBX5-AS1 other 1 1 1 -0.459407314920505 -0.337839022740799 1.84484077262737e-05 158.264923082741 37.582608145221 4.21112133759313 3.48475276834287e-05 10.4574940508404 67.4269922667972 0.155093586400263 0.876865602539873 PCDHA3 other 0.147734849072 1 0.341714856463702 4.21112133759313 0.155093586400263 0.0753219113810063 2.47559638007005 1.98886239575553 1.2447298442332 0.214302468687427 -5.24862707258326 4.24872937104393 -1.23534040750015 0.217769780819152 EBLN2 other 1 1 1 1.2447298442332 -1.23534040750015 0.405693736131379 -4.17022249904556 8.70593931728357 -0.479008909557476 0.632318565372539 -25.8661621322965 19.2247583320076 -1.34546097722495 0.179601087314865 CARD18 other 1 1 1 -0.479008909557476 -1.34546097722495 0.109914112759129 1.41975658828865 1.96772941137974 0.721520235494746 0.471228012224723 -5.28919067142873 3.8846962527274 -1.36154549219009 0.17450220058493 NPIPB8 other 1 1 1 0.721520235494746 -1.36154549219009 5.48055287541412e-24 368.851311925914 48.187967299252 7.65442770464484 3.3949986458326e-13 -296.49244027004 94.435633233476 -3.13962463233569 0.00187801394765086 NEDD8-MDP1 other 8.3403053658052e-20 1 4.83515707139479e-09 7.65442770464484 -3.13962463233569 7.18603277124118e-15 177.395102690865 30.4497394282985 5.82583319337055 1.60177235964399e-08 -201.033986971477 59.0588874147661 -3.40395824864817 0.000764227103006717 POLR2M other 9.46184934989326e-11 1 0.000196969947065421 5.82583319337055 -3.40395824864817 3.27631990264773e-11 15.3937040333671 5.77100137549831 2.66742338664542 0.00810363053596694 -43.6359090813996 10.2306893203052 -4.2651973601421 2.76188593573691e-05 FDXACB1 other 3.80642846289614e-07 0.420165707403657 1 2.66742338664542 -4.2651973601421 0.531069124120717 5.2639488171403 8.68147591687447 0.606342615880393 0.544791116906543 16.9974251516804 15.1452356074163 1.12229519515412 0.262723036572407 PCDHB17P other 1 1 1 0.606342615880393 1.12229519515412 0.137566913539633 11.1740482573725 23.0359645917497 0.485069692344227 0.628017343843965 -106.574259912516 63.3474369198467 -1.68237682682196 0.0936433444813536 TRIL other 1 1 1 0.485069692344227 -1.68237682682196 1.33593862305166e-05 531.226574110995 119.341563566619 4.45131233607857 1.24810328342338e-05 -95.9389386305134 243.843870798385 -0.393444126015526 0.694300839620981 SNHG1 other 0.108251106625876 1 0.127156762515174 4.45131233607857 -0.393444126015526 2.50329626241089e-05 76.7487280243494 23.4274264290521 3.27602044794702 0.00118889468381448 -130.496010879935 62.7428444892773 -2.07985487336706 0.0384718251670371 AGAP2-AS1 other 0.19776040473046 1 1 3.27602044794702 -2.07985487336706 0.712446370860191 2.4434082371659 7.6246648133616 0.320461069040573 0.74886488869636 27.4961609097362 34.09514121881 0.806453938210022 0.420685699487834 KLRC4 other 1 1 1 0.320461069040573 0.806453938210022 0.195962582602965 -11.7238915174869 6.64009430251752 -1.76562123719266 0.0785772188959216 -5.37538766795008 11.0455046588313 -0.486658403937411 0.62689089192929 TIFAB other 1 1 1 -1.76562123719266 -0.486658403937411 1.77587029930819e-10 13.2978013392211 2.12157530485268 6.26789033073916 1.43527298890735e-09 -6.54310567345921 6.25510969546904 -1.04604171501561 0.29647387419448 TMEM5-AS1 other 1.99519028127275e-06 1 1.84475637264261e-05 6.26789033073916 -1.04604171501561 0.0254494714430566 154.749134183625 84.4836774919134 1.83170452302383 0.068101180605618 -236.740046097258 176.449869873418 -1.34168444707322 0.180829821481397 PXN-AS1 other 1 1 1 1.83170452302383 -1.34168444707322 0.529648943417285 2.85971857835829 2.63413218847043 1.08563973777598 0.278621298058284 -1.50472339140448 17.0862667784688 -0.0880662470575872 0.929890286334769 DENND5B-AS1 other 1 1 1 1.08563973777598 -0.0880662470575872 4.70273588060813e-07 33.0518057836798 7.97478846942371 4.14453698808493 4.58547590841483e-05 -24.9039582450531 15.7417362001506 -1.58203376860138 0.114834597096222 LINC00346 other 0.00430394387793256 1 0.444424325043565 4.14453698808493 -1.58203376860138 0.742194448240622 -10.4414083662813 19.6058423165777 -0.532566170720073 0.594771933530728 -47.903883658751 69.19734913872 -0.692279173335355 0.489356959850744 CYP2A6 other 1 1 1 -0.532566170720073 -0.692279173335355 0.41506418761441 1.86490625197178 3.58193907174477 0.520641533710782 0.603040060118029 -4.33970130708488 6.4344224844855 -0.674450786772029 0.500597583131335 MT1JP other 1 1 1 0.520641533710782 -0.674450786772029 0.364731638289105 8.14439385656834 9.6691187846897 0.84230983587298 0.400357280664015 25.1405223863833 17.9778369799225 1.39841753012112 0.163131007896717 PAPPA-AS1 other 1 1 1 0.84230983587298 1.39841753012112 1.25899561329408e-09 -52.9353764890356 65.5909259831113 -0.807053349157865 0.420338304638493 -563.709400533712 97.2321581765489 -5.79756133264222 1.85501232683543e-08 CTSO other 1.35316848516848e-05 0.000294390456268783 1 -0.807053349157865 -5.79756133264222 1.09048484484969e-23 233.781799802269 23.6423763622497 9.88825303430808 7.55738391426931e-20 -40.9756829552399 55.567222237804 -0.737407437425638 0.461522143077188 APOPT1 other 1.6555740914508e-19 1 1.15635531272235e-15 9.88825303430808 -0.737407437425638 4.22330540203919e-10 32.4932117287069 6.17473751478015 5.26228226721048 2.88845722771245e-07 -24.7246011704941 13.7610320871275 -1.79671125057708 0.0734908707856511 TRAPPC2B other 4.65746119736882e-06 1 0.00332201465759209 5.26228226721048 -1.79671125057708 0.00575670314137274 15.428984970875 6.05524657999018 2.54803578467982 0.0113896583851263 -9.30004988253465 11.7731104887727 -0.789939913619561 0.430258639219115 DNAAF4 other 1 1 1 2.54803578467982 -0.789939913619561 0.000421697565030589 5.7000034904768 1.53569953221187 3.71166583756594 0.000250051925454409 14.9984725008602 6.96646438798577 2.15295330106421 0.0322082256830037 A2MP1 other 1 1 1 3.71166583756594 2.15295330106421 3.95080997829843e-05 31.4347063363973 10.9991811514057 2.85791332133666 0.00459778472750558 -26.6090697453637 15.7472262196458 -1.68976233491629 0.0922319686431582 URB1-AS1 other 0.305713676120733 1 1 2.85791332133666 -1.68976233491629 1.00791907551004e-05 34.8934169864345 13.405417129064 2.6029340713899 0.00974822153492139 -92.723390035696 32.049575623228 -2.89312380063138 0.004121790390722 ZNF432 other 0.0825586514750277 1 1 2.6029340713899 -2.89312380063138 3.33100460921354e-06 27.7651189030545 5.7752993390517 4.80756360372716 2.53138280284171e-06 -24.0232192115483 26.6813988531916 -0.900373302904046 0.368718091415556 CCND2-AS1 other 0.0283768282658901 1 0.0272629927866052 4.80756360372716 -0.900373302904046 0.0755346588886574 4.48121461657229 14.7001369322806 0.304841692102325 0.760723325543277 -65.1558984189495 30.3534686662075 -2.14657175215983 0.0327250862260677 ZNF10 other 1 1 1 0.304841692102325 -2.14657175215983 0.00187048453300405 130.81004139011 37.465151478953 3.49151241156989 0.000560891932738121 65.2180598915501 84.6976558955782 0.770010211049476 0.441967008733368 ZNF486 other 1 1 1 3.49151241156989 0.770010211049476 0.326583159870131 70.0199840225843 56.3059846345496 1.24356202057463 0.214727609167275 -14.4380466710442 93.9623124566137 -0.153657847423783 0.877993044028939 SMIM3 other 1 1 1 1.24356202057463 -0.153657847423783 7.88194440258421e-13 213.803794079401 37.3373253575027 5.72627503529623 2.7213042206459e-08 -110.373257495456 67.1067750205114 -1.64474089928655 0.101182679995564 HMBS other 9.75311800375771e-09 1 0.000330883380188335 5.72627503529623 -1.64474089928655 2.84186476183558e-13 22.0942493995248 3.74095717022023 5.90604179470574 1.03905915609378e-08 -31.7415776188002 10.2764248347396 -3.08877631367451 0.00221710801863466 ZNF225 other 3.57080307324641e-09 1 0.000128926460088116 5.90604179470574 -3.08877631367451 0.214663584718265 -1.44718118606103 2.91191208977851 -0.496986564649726 0.619602954960894 -9.70721952139192 5.6979813090874 -1.70362431795106 0.0896018930789451 ABCC6P1 other 1 1 1 -0.496986564649726 -1.70362431795106 0.00552794711149146 2.02789011584985 0.656711305091616 3.08794762649463 0.00224559735678447 -2.12112660706153 2.21434497278051 -0.957902509832547 0.339048578328541 PPIAL4D other 1 1 1 3.08794762649463 -0.957902509832547 7.7076514076072e-12 26.0240416349327 5.92471325590868 4.39245588957054 1.60911245421487e-05 -31.6768723026149 9.810888472876 -3.22874654932541 0.00139643624240496 DND1 other 9.17750053103789e-08 1 0.162439902252992 4.39245588957054 -3.22874654932541 0.000250798295803189 69.0634135503018 20.3246807647266 3.39800729712622 0.000786984473902778 -7.58967847966884 30.5633761652449 -0.248325919186226 0.804081330343092 SALL3 other 1 1 1 3.39800729712622 -0.248325919186226 2.13762801809476e-10 58.8543834828703 9.05947986164139 6.49644178051158 3.90060872291706e-10 -19.5108473383625 20.077474214709 -0.971777980124043 0.332024384587742 POLG2 essential 2.39478466867156e-06 1 5.11408809661656e-06 6.49644178051158 -0.971777980124043 3.09225222640219e-13 238.127318819039 30.354317145153 7.84492425510101 9.83767519935258e-14 43.2628981931637 132.569723361612 0.32634071412486 0.74441661997163 SMIM10L1 other 3.87799351713099e-09 1 1.41180476785909e-09 7.84492425510101 0.32634071412486 0.518608285380755 -1.59867309017454 1.93627769552296 -0.825642465371042 0.409733169860967 -3.87102236252379 4.01918792840727 -0.963135447129442 0.336338170649256 LINC02361 other 1 1 1 -0.825642465371042 -0.963135447129442 0.805989708981378 -15.6243501622414 73.643198357789 -0.212162840705694 0.832140070871091 -170.519538746031 259.567781973753 -0.656936455862901 0.511781334734141 CYP2B7P other 1 1 1 -0.212162840705694 -0.656936455862901 0.345857879715634 -121.531206564234 88.0521316330616 -1.38021878982657 0.168665218620206 -75.5526562217862 215.196472932317 -0.351086870487645 0.725797988499083 MTRNR2L1 other 1 1 1 -1.38021878982657 -0.351086870487645 5.05233856872208e-15 46.3029827820018 6.38868225127575 7.24765780498093 4.67844058389759e-12 -61.5400353119081 23.5430409445399 -2.61393740328097 0.00946447898546339 ZBTB11-AS1 other 6.68778056341742e-11 1 6.48665786957401e-08 7.24765780498093 -2.61393740328097 1.59687368117795e-05 29.8195203017488 7.95190847317388 3.74998283774849 0.000215923297026487 -26.4399179029463 19.0113660400337 -1.39074266663794 0.165436036488708 ZNF350 other 0.128484456387578 1 1 3.74998283774849 -1.39074266663794 0.183223264382177 3.22850025233815 1.84448148886458 1.75035654834657 0.0811842993707148 -1.08327373857766 7.70807909389312 -0.140537444593155 0.888339386736871 PLBD1-AS1 other 1 1 1 1.75035654834657 -0.140537444593155 2.31533306857083e-05 56.5716658388176 12.7718263665473 4.42941081527646 1.37409291639894e-05 14.6395198772418 29.5526232590231 0.49537124839745 0.620741005822551 ZNF253 other 0.183582759006981 1 0.139470431014493 4.42941081527646 0.49537124839745 0.000123124564321385 132.453747234514 72.0483199405779 1.83840160802855 0.0670895315012767 -269.665237831859 128.901597300795 -2.09202402048275 0.0373601206833337 CAPNS2 other 0.902010558218465 1 1 1.83840160802855 -2.09202402048275 0.482173252996051 -9.58292590578238 10.2982523204784 -0.930539047555323 0.352923301903311 -21.5340029873631 21.2494498068417 -1.01339108462139 0.311780654470056 SLC5A8 other 1 1 1 -0.930539047555323 -1.01339108462139 0.595895403702551 11.1911846850397 16.9146261539047 0.661627669639997 0.508789117423422 -21.1526615677667 39.227372857215 -0.539232174552218 0.590182849725562 KHDC1L other 1 1 1 0.661627669639997 -0.539232174552218 0.476720771339644 -304.499865172947 250.926749277259 -1.21350101593391 0.22600275530111 -246.853123435044 429.475623395191 -0.574777961746845 0.565921861315012 HP other 1 1 1 -1.21350101593391 -0.574777961746845 0.00369269700898601 16.4761566470304 4.98774577058871 3.30332727545688 0.00108396554997409 31.2853634440204 23.9607983638308 1.30568952540606 0.192765477464096 MIR200CHG other 1 1 1 3.30332727545688 1.30568952540606 1.54158162310384e-05 128.135579876463 72.8087507238663 1.75989257613317 0.0795459561387773 -687.336670660771 196.965541821545 -3.4896290198999 0.000563752792446877 KIAA1147 other 0.124282310454632 1 1 1.75989257613317 -3.4896290198999 2.88193617201155e-30 1071.72491976191 84.3464274789533 12.7062277774519 3.00887311857663e-29 -201.037642454874 290.990523506462 -0.690873503481667 0.490245224986781 LSM14A other 4.51743494962811e-26 1 4.74047959831748e-25 12.7062277774519 -0.690873503481667 0.00811464101737457 -7.95489286744246 4.34854713688484 -1.82932198204044 0.0684582650792729 -24.9674167374648 7.97752219814065 -3.12972074753789 0.00194236801610676 NHLRC4 other 1 1 1 -1.82932198204044 -3.12972074753789 1.53479428980189e-05 61.3221763908603 16.3775784775321 3.74427614405795 0.000220642860728803 -62.2860615148186 34.7565358185082 -1.79206759384952 0.0742294320802908 TMPO-AS1 other 0.123781159472522 1 1 3.74427614405795 -1.79206759384952 7.5200162051527e-14 560.803792558835 82.4741800305306 6.79974984111675 6.67243431795686e-11 -385.949020323455 172.093076324326 -2.24267604814093 0.0257263112976796 GATC other 9.62513988532532e-10 1 8.97042069706121e-07 6.79974984111675 -2.24267604814093 0.167188207100419 -0.820189531196935 7.05127007623391 -0.116317985601113 0.907486364902887 -29.977350149096 16.160184062803 -1.85501291523634 0.0646763321956613 LINC01619 other 1 1 1 -0.116317985601113 -1.85501291523634 2.06321651819028e-23 213.644783884733 22.9345517873458 9.31541134379665 4.97550092097229e-18 -77.7345512547478 41.4552849332657 -1.87514212916119 0.0618770022118718 ZNF271P other 3.12577302505827e-19 1 7.52146474223382e-14 9.31541134379665 -1.87514212916119 0.0198087216493467 45.8243342491093 16.3311370000718 2.80594879884406 0.0053792042324261 -1.9386557136251 48.0722820140089 -0.0403279318643569 0.967861270300198 ZBED6 other 1 1 1 2.80594879884406 -0.0403279318643569 0.651176459784198 -1.25801211732538 10.1352714313123 -0.124122193061236 0.901309866169976 -24.6354099863863 27.418396952696 -0.89849928239382 0.369711189248274 MGAM other 1 1 1 -0.124122193061236 -0.89849928239382 5.13628948982868e-21 158.477615144224 23.1402795370386 6.84856096446727 4.93013099701959e-11 -150.159006921633 42.8961650664269 -3.5005228716624 0.000542160477172202 FNTB other 7.60479021864034e-17 1 6.65321178047793e-07 6.84856096446727 -3.5005228716624 0.774412426539001 -4.92575410173782 6.88593386412877 -0.715335668179706 0.475015224219064 -4.54616755899282 18.5512534710487 -0.245059858951721 0.806594865956589 KRT73-AS1 other 1 1 1 -0.715335668179706 -0.245059858951721 0.852964983553513 6.49208562289837 12.0478963231127 0.538856365359315 0.590425099564958 1.07697039284834 31.4468193545017 0.0342473552160427 0.97270493109663 OR7E47P other 1 1 1 0.538856365359315 0.0342473552160427 0.37108058853733 2.69110643831573 3.69311071050824 0.72868285011293 0.46682723686858 -5.78470583551011 8.0320354327846 -0.720204222692856 0.47202227741013 ZNF625 other 1 1 1 0.72868285011293 -0.720204222692856 0.00155729794419639 81.6018948381282 29.5229486047686 2.76401574688742 0.00609955203222707 -102.01975023336 67.9788557544487 -1.50075709720494 0.134578285991919 GALNT4 other 1 1 1 2.76401574688742 -1.50075709720494 8.23036655707728e-06 108.207640808874 36.521720448109 2.96282977584855 0.00331788503907118 -131.47602649314 67.7118646220979 -1.94169850774177 0.0532060928184406 PSMA3-AS1 other 0.0678840633627734 1 1 2.96282977584855 -1.94169850774177 0.970630648173052 60.7878473076536 254.736596600594 0.238630209082066 0.811571366445354 23.882639857113 664.900786115812 0.0359191030539 0.971373113263294 KRT7-AS other 1 1 1 0.238630209082066 0.0359191030539 0.0900257101338146 24.2374459333222 11.1389774011866 2.17591301789878 0.0304289507177355 22.1599061591996 47.9922618236745 0.461739149544899 0.644640191893934 LBX2-AS1 other 1 1 1 2.17591301789878 0.461739149544899 1.11845224441723e-06 11.8357203385632 9.31613146989598 1.27045441305858 0.205008417309267 -79.563687728891 19.1490046629458 -4.15497771969582 4.36077706891694e-05 INAFM1 other 0.00992402676471411 0.659741962756444 1 1.27045441305858 -4.15497771969582 2.215823723114e-08 202.408190655414 51.3954049223954 3.93825461558363 0.000104356878083838 -427.757589445491 136.818747381988 -3.1264545073726 0.0019610974519937 CNPY2 other 0.000220984099906159 1 0.976780378864724 3.93825461558363 -3.1264545073726 0.570842582885843 3.27750953522122 19.8769294383859 0.164890132823622 0.869152485627454 -48.9159030051417 53.7719729792996 -0.909691430217237 0.363787697945657 MGAM2 other 1 1 1 0.164890132823622 -0.909691430217237 4.51174558160386e-12 14.6668861273421 2.25741140525691 6.49721450559999 3.94506687076721e-10 -22.2664664088004 9.29952214715541 -2.39436672728516 0.0173339797731234 LINC01481 other 5.41409469792463e-08 1 5.1704046408275e-06 6.49721450559999 -2.39436672728516 0.692582061095522 -19.9723278231031 29.8571261073568 -0.668930015276384 0.504109551069911 -47.6736078481627 68.3791673131816 -0.697194916542549 0.486278477899718 LINC02404 other 1 1 1 -0.668930015276384 -0.697194916542549 2.70002055930662e-14 991.133721659952 127.562049531065 7.76981653480394 1.68157537006359e-13 -543.989995169689 518.956634407627 -1.04823786633085 0.295473431145657 CUX1 other 3.50165666336476e-10 1 2.40482093672794e-09 7.76981653480394 -1.04823786633085 2.52216715057564e-07 115.661768296846 20.5965032843605 5.61560215828828 4.84787231377159e-08 22.7658102427546 47.3020635777652 0.481285773195229 0.630701783025842 TEN1 essential 0.00235267751805696 1 0.000583150560623584 5.61560215828828 0.481285773195229 1.91403578726583e-06 525.306448695337 149.896473259308 3.50446169461639 0.000534546005122632 -1249.51275267943 449.689419777925 -2.77861274409455 0.00583802349410915 P2RX5-TAX1BP3 other 0.0166731657428726 1 1 3.50446169461639 -2.77861274409455 9.18614929613591e-08 21.7617089964438 4.99103325208901 4.36016109236207 1.84317862510083e-05 -27.8057927059951 12.7410997382085 -2.18236991133584 0.0299346223539074 BCDIN3D-AS1 other 0.000881502886457202 1 0.185257883608884 4.36016109236207 -2.18236991133584 0.281803468924486 27.1280462627101 17.2868193043618 1.56929078652804 0.117742751005498 26.3382499250623 36.5202682804361 0.721195411896022 0.471408720209842 MAP1LC3B2 other 1 1 1 1.56929078652804 0.721195411896022 0.0912419207330488 -22.1317767576872 10.1896938916616 -2.17197660626469 0.0307182376337064 -30.9704689416186 27.5656230660874 -1.12351782752627 0.262204639065723 CLEC5A other 1 1 1 -2.17197660626469 -1.12351782752627 1.00850852725882e-08 203.959792419664 51.693711010283 3.9455436344876 0.000101313216888796 -218.519234757362 95.998810840056 -2.27627022507016 0.0236043463686507 CHURC1 other 0.000102736763671856 1 0.949912721549355 3.9455436344876 -2.27627022507016 0.013445269626561 24.0300432086063 17.9658996664241 1.3375363135037 0.182164959506067 -58.1320008230211 33.6372060665661 -1.72820538982879 0.0850863036111068 VASH1-AS1 other 1 1 1 1.3375363135037 -1.72820538982879 2.22901390048468e-08 276.406832717772 46.0580076201228 6.0012763686506 6.20714774622913e-09 54.8734935748066 137.979966469159 0.397691744526346 0.691168209326921 C17orf49 other 0.000222232685878323 1 7.77569398170124e-05 6.0012763686506 0.397691744526346 1.51911804516634e-20 13.2550126430633 1.30708685194354 10.1408813219673 1.0716159420516e-20 -3.04808022057915 6.1749830087273 -0.493617588302867 0.621976079403556 ITFG2-AS1 other 2.23538220346227e-16 1 1.64610924858547e-16 10.1408813219673 -0.493617588302867 9.67360773357333e-06 152.773843620536 31.8884646717236 4.79088112874888 2.74294720428551e-06 20.6123308602291 89.2821735144356 0.230867261054038 0.817592767967616 RTEL1 other 0.0793912986694364 1 0.0294674818156393 4.79088112874888 0.230867261054038 1.59022147809778e-20 349.472576564261 39.8874039123321 8.76147711524071 2.14305471438761e-16 -111.060192388185 76.1796144217509 -1.4578728604916 0.146033459790144 PPT2-EGFL8 other 2.33937481642964e-16 1 3.19102533513409e-12 8.76147711524071 -1.4578728604916 0.36381404123508 -23.0520341385501 33.6911374716615 -0.684216558670356 0.494434089919837 -106.376521075079 74.7212339974824 -1.42364513250227 0.155721126551162 MEG8 other 1 1 1 -0.684216558670356 -1.42364513250227 7.00141513730748e-20 86.3723944948889 11.1972425442434 7.71372006577579 2.3654683322347e-13 -35.1724876576181 20.2950560700636 -1.73305693446689 0.0842272891846315 PDF other 1.02185653929003e-15 1 3.37623295059858e-09 7.71372006577579 -1.73305693446689 0.538772211761704 -4.89997028447607 11.5748935895823 -0.423327458395484 0.672390889998978 16.1955001138695 24.542350607368 0.659900120121639 0.509876309287364 LINC00641 other 1 1 1 -0.423327458395484 0.659900120121639 9.26965623720012e-06 13.9837080550116 2.86534137165062 4.88029391309701 1.81380801255714e-06 9.31737699454232 5.4852486429592 1.69862436527868 0.0905419354229609 LINC00640 other 0.0762058439260222 1 0.0197469278327096 4.88029391309701 1.69862436527868 0.954098382748205 -2.33728329491893 14.0195395356531 -0.166716124233252 0.867718201726822 -8.1398822141879 26.915320945291 -0.302425604759955 0.762560482733021 SPESP1 other 1 1 1 -0.166716124233252 -0.302425604759955 0.486474939334782 0.924225760041558 6.61637555060904 0.13968762095986 0.889010949319293 -14.8747592497429 14.6656552519219 -1.01425807399868 0.311367647181624 MIR1247 other 1 1 1 0.13968762095986 -1.01425807399868 1.62413820014312e-09 204.893713383115 37.873477063326 5.40995253856741 1.38643886350873e-07 -189.648182472794 109.93877223873 -1.72503456797731 0.0856613225764384 SPECC1L-ADORA2A other 1.73490442539288e-05 1 0.00162629278689574 5.40995253856741 -1.72503456797731 0.16899574610849 -1.51137872444949 1.01943867463534 -1.48255972826429 0.139349082449361 0.518241836455432 1.8900559086617 0.274193918857345 0.784143720904937 LINC01500 other 1 1 1 -1.48255972826429 0.274193918857345 0.000470308233379835 3.65088530511502 15.6219249411962 0.233702653089016 0.815391620663489 -70.504583076197 23.6903700862 -2.97608618268345 0.00318214481803747 TRIM6-TRIM34 other 1 1 1 0.233702653089016 -2.97608618268345 1.70462612296569e-15 323.618143359935 52.0225580189811 6.22072723224911 1.86003886955469e-09 -210.926306085198 105.634817635004 -1.9967498482745 0.0468487839149275 BCL2L2-PABPN1 other 2.28266484126335e-11 1 2.37991973359523e-05 6.22072723224911 -1.9967498482745 9.24280368105591e-16 245.205220689136 35.0202204969297 7.00181829839232 1.97663629329431e-11 -94.5027357369958 64.2954675326655 -1.46981955903787 0.142766349398587 SYNJ2BP-COX16 other 1.24639207639039e-11 1 2.69712022220009e-07 7.00181829839232 -1.46981955903787 0.00378399133539015 -3.36358541764981 13.6728772941541 -0.246004212960203 0.805864504071968 -58.0771590372817 20.7346741493759 -2.80096801227184 0.00546052574373775 TRIM34 other 1 1 1 -0.246004212960203 -2.80096801227184 7.44159843934001e-15 21.1248075067883 2.73314788995108 7.72911249495774 2.27352038952009e-13 -1.40220295411491 6.46025263878978 -0.217050792363066 0.828336405137384 LINC00638 other 9.79612018554718e-11 1 3.24635976419574e-09 7.72911249495774 -0.217050792363066 2.04178619449882e-10 21.3588522664027 4.82641648528159 4.42540595730552 1.41936284050234e-05 -19.4408861307435 9.02751424729472 -2.15351486557547 0.0322013928194959 SLC25A21-AS1 other 2.28884232403318e-06 1 0.143923392026937 4.42540595730552 -2.15351486557547 4.01404225587248e-13 109.383576359624 14.9592632124117 7.31209651213758 2.9692862303117e-12 -26.7665766178337 35.918957969449 -0.745193572725583 0.456800501415466 PRC1-AS1 other 5.01715141561501e-09 1 4.13977886230057e-08 7.31209651213758 -0.745193572725583 0.000289888953095037 21.8699359192423 8.14697767001176 2.68442320638037 0.00771144450767309 -18.9588964502608 14.5867873302861 -1.29973077833917 0.194793673757996 HIF1A-AS1 other 1 1 1 2.68442320638037 -1.29973077833917 0.676372925257458 -13.0393254897805 42.347095631317 -0.307915461388514 0.758382316456064 -79.3264373644754 90.6969793653364 -0.874631524881779 0.382546045021074 RNASE4 other 1 1 1 -0.307915461388514 -0.874631524881779 0.153461497255875 20.8397696927222 32.3079273896565 0.645035796985048 0.519470568440183 -59.9515682080903 52.6451176364071 -1.13878686001132 0.255836214204322 MC1R other 1 1 1 0.645035796985048 -1.13878686001132 0.825534225195407 -1.22092237147644 2.69588935136366 -0.452882968234161 0.650994047890605 0.842303283266217 5.04746143127768 0.166876616044395 0.867591122037254 TGFB3-AS1 other 1 1 1 -0.452882968234161 0.166876616044395 7.79457494974746e-08 149.096765175761 27.1690511855228 5.48774280550542 9.32236663298666e-08 -53.0019321997509 60.211616223695 -0.880260911828724 0.379495060406266 CEP95 other 0.000751474635204607 1 0.00110423432767727 5.48774280550542 -0.880260911828724 2.35226100380915e-21 36.2097702494034 3.67375422063958 9.85633988413615 8.93040016971108e-20 3.88753450938188 7.94859102185025 0.489084731960074 0.625178767899971 FOXN3-AS1 other 3.49616552996153e-17 1 1.36581540195561e-15 9.85633988413615 0.489084731960074 0.0130237406596921 445.83197597844 241.574909639011 1.84552268546702 0.0660941275965747 -339.351786512649 393.641454698259 -0.862083458086941 0.38943296311844 TUBB3 other 1 1 1 1.84552268546702 -0.862083458086941 7.05641591729379e-15 134.203170856363 34.3038302609694 3.91219201574286 0.000115613533370735 -250.915218702295 54.8360003564274 -4.57573887722256 7.22077309187303e-06 UBE2F-SCLY other 9.2925941214842e-11 0.111430970353785 1 3.91219201574286 -4.57573887722256 0.55809001112542 7.13594357617066 9.83935876360628 0.725244779422518 0.468959155678489 -9.91911500150332 23.379545272336 -0.42426466751003 0.671726351259164 TMEM179 other 1 1 1 0.725244779422518 -0.42426466751003 2.59718029695302e-06 84.9600439882696 24.1221663645831 3.52207354448108 0.000501992654228462 -132.18441748867 62.6936029007072 -2.10841954159216 0.0359092355869099 TVP23C-CDRT4 other 0.0223279590129051 1 1 3.52207354448108 -2.10841954159216 0.000380658563572735 8.59935233331778 6.16057745761182 1.39586790239812 0.163892591187448 -26.4203855650728 10.6856223969345 -2.47251723705418 0.0140283592937978 FPGT-TNNI3K other 1 1 1 1.39586790239812 -2.47251723705418 0.00025280814998017 903.397510459834 319.833461206019 2.82458723065851 0.00508719809609583 -965.822085665171 576.005265455775 -1.67675912632664 0.0947469517659461 BLOC1S5-TXNDC5 other 1 1 1 2.82458723065851 -1.67675912632664 0.0838424669993628 -9.89994047288529 5.69444642705338 -1.7385255265292 0.0833020301390094 2.65555700954099 10.6380448467035 0.249628296158564 0.80307192122771 LINC00639 other 1 1 1 -1.7385255265292 0.249628296158564 0.000927482286739395 83.5143490400388 28.9662888991068 2.8831566698423 0.00425161389993197 -103.406724043638 66.6971040452246 -1.55039301216919 0.122209933141051 POC1B-GALNT4 other 1 1 1 2.8831566698423 -1.55039301216919 1.02298907847845e-21 543.718493004552 55.4892055709716 9.79863538159915 1.36174811703439e-19 -48.2509916854639 139.656848158948 -0.345496782445984 0.729989952658322 NDUFC2-KCTD14 other 1.52670890072124e-17 1 2.08061494801684e-15 9.79863538159915 -0.345496782445984 0.908709365399232 -0.666390314813973 2.0381883162377 -0.32695227889642 0.743954520657811 -2.09145448144279 5.45863340784965 -0.383146169595346 0.701909560961622 LRP1-AS other 1 1 1 -0.32695227889642 -0.383146169595346 0.000269256052878086 27.5787490882337 7.51111903168364 3.67172307773318 0.000292392075729326 4.93517814024831 13.6493292271919 0.361569279933298 0.717967579443665 LINC00648 other 1 1 1 3.67172307773318 0.361569279933298 0.209734572357637 2.26979765841866 1.44762709151226 1.56794361733553 0.11812469182634 0.0608090740360126 3.0728090251263 0.0197894088239061 0.984226721856113 CHEK2P2 other 1 1 1 1.56794361733553 0.0197894088239061 3.06252567883516e-06 15.6038488610395 3.02519553738331 5.15796373101104 4.81561852720027e-07 13.0274994626885 5.51931918816696 2.3603453648085 0.0189640234532917 ADAM20P1 other 0.0261723444513253 1 0.00544983548723254 5.15796373101104 2.3603453648085 0.394754911771699 -1.21397442864205 8.59058068314574 -0.14131459483569 0.88772718972869 22.4914726356002 18.3048084755881 1.22871936440065 0.22025088130608 ITGB3 other 1 1 1 -0.14131459483569 1.22871936440065 0.841536226210014 -2.70570213480317 4.65392661286202 -0.581380490041559 0.561470874307368 -1.8278158604031 8.13280237630006 -0.224746130033796 0.822347400606102 LINC02345 other 1 1 1 -0.581380490041559 -0.224746130033796 0.0333337944499912 4.11519551926542 1.65702094410138 2.48349034688704 0.0136220306005086 1.34985135548587 3.67437023731037 0.367369445185242 0.71363339177747 LINC02323 other 1 1 1 2.48349034688704 0.367369445185242 0.000128445969836738 4.57960320595658 1.13907627551391 4.02045350640844 7.52114033440441e-05 -0.0747822185916103 2.20730837209996 -0.0338793707018223 0.972998100751693 ANKRD34C-AS1 other 0.938683147566882 1 0.715110022995171 4.02045350640844 -0.0338793707018223 1.16826296825181e-10 51.8311464448911 10.0241237488712 5.17064111970163 4.52746020012819e-07 -47.0844881419667 19.895172130298 -2.36662884008239 0.0186516907960607 USP3-AS1 other 1.32445972710707e-06 1 0.00513640359704543 5.17064111970163 -2.36662884008239 1.13257390425662e-09 106.941213778888 30.7899821230885 3.47324702402786 0.000597743774571805 -168.385008216305 53.408731099664 -3.15276181907576 0.00179770478530703 BUB1B-PAK6 other 1.2194423227131e-05 1 1 3.47324702402786 -3.15276181907576 0.00802855351393709 37.0432119819258 12.2130383055273 3.03308734937488 0.00265454503477877 4.03579942866788 29.3720837660702 0.137402557503595 0.890814263985897 ZNF710-AS1 other 1 1 1 3.03308734937488 0.137402557503595 1.93156933777996e-08 68.7587659938979 11.4155305089198 6.02326505458257 5.59521137003829e-09 -12.7750079705403 49.4281888353053 -0.25845591901226 0.796252706684402 ZHX1-C8orf76 other 0.000193350090711774 1 7.02031170598704e-05 6.02326505458257 -0.25845591901226 1.54588390904914e-08 109.500504316525 20.1402459159139 5.43690006436329 1.20347022640571e-07 -35.6553405239988 39.470308258669 -0.903345884464119 0.367138742290729 ST20-MTHFS other 0.000155577756606706 1 0.00141660480350216 5.43690006436329 -0.903345884464119 3.748426581746e-07 533.960103792159 115.151700878454 4.63701447498174 5.52064578056381e-06 -907.807488999556 478.770649974313 -1.89612184675118 0.0590154610901064 TGIF2-C20orf24 other 0.00345642415102798 1 0.0578839710092115 4.63701447498174 -1.89612184675118 0.00972060897088426 9.94125644561377 5.36022200961791 1.85463520499264 0.0647385018693345 -17.1810020845389 10.4394689032125 -1.64577357754778 0.100973926279788 UBE2Q2P2 other 1 1 1 1.85463520499264 -1.64577357754778 8.06023589596536e-19 158.756973634043 23.9278969630748 6.63480680642493 1.74030866130245e-10 -131.690014777828 48.5993173853433 -2.70970914537049 0.00716038375738529 THTPA other 1.15728866994271e-14 1 2.30991168614674e-06 6.63480680642493 -2.70970914537049 7.25513510015814e-07 29.5027754361198 10.353178875779 2.84963447363405 0.00471169725101773 207.139413128971 41.6453777406681 4.97388724431457 1.164390800262e-06 LINC01833 other 0.00653107261716235 0.0182099077252974 1 2.84963447363405 4.97388724431457 1.15996081872457e-07 5.31063965657925 1.14472207536826 4.63923931480994 5.46591902826882e-06 -8.29162113740379 3.82803217718731 -2.1660270221386 0.0311876520597068 ADNP-AS1 other 0.0011063706288995 1 0.0573429565255682 4.63923931480994 -2.1660270221386 1.61952490518986e-16 111.272595329743 14.4955757439367 7.67631429722868 2.9785847629695e-13 -67.7240818337051 29.2723650488713 -2.31358421913082 0.0214390894303834 MRPL46 other 2.22360769482568e-12 1 4.24567472113673e-09 7.67631429722868 -2.31358421913082 9.77408879125751e-06 45.2229984283707 9.94562451588371 4.54702450873216 8.24672914304974e-06 13.2321274147824 17.7150833997412 0.746941299467755 0.455753786021381 ANP32AP1 other 0.0801768503546853 1 0.0852876727974204 4.54702450873216 0.746941299467755 1.78342735299399e-07 3.31410841568138 0.827571333956611 4.00461963784639 8.02746355902386e-05 -2.16916528500838 1.43365674489264 -1.51302973514125 0.131437415891529 INO80-AS1 other 0.00168016690925564 1 0.760762721488691 4.00461963784639 -1.51302973514125 2.35277552065405e-09 33.0532575807874 6.98610116757302 4.73128813739612 3.58971891271944e-06 -29.6815784731247 13.4926011864537 -2.19984108793821 0.0286593688643107 IQCH-AS1 other 2.49229510902883e-05 1 0.0381910195124221 4.73128813739612 -2.19984108793821 0.564139219468233 30.3216665584016 29.0604432444512 1.04340000265451 0.29768612710453 -2.00111787740953 112.178508189333 -0.0178386921854235 0.985780567921604 HSP90B2P other 1 1 1 1.04340000265451 -0.0178386921854235 1.30034173865248e-10 5.26772667637607 0.839549964959581 6.27446476831154 1.37064970492246e-09 -2.5409746426465 2.02694797092776 -1.25359638189601 0.211061226104241 CRTC3-AS1 other 1.47055647224209e-06 1 1.76279258550077e-05 6.27446476831154 -1.25359638189601 0.0901414294265414 -92.5962318206752 51.2886222081405 -1.80539518969528 0.0721350036211681 -175.28327872741 84.5693327839075 -2.07265769939673 0.0391600802678576 SLC22A31 other 1 1 1 -1.80539518969528 -2.07265769939673 0.268992000408654 -2.25612457023476 2.92667738970366 -0.770882564020219 0.441487426340395 -11.9201420952499 7.87987663723319 -1.51273206980501 0.131581242409194 LYPD8 other 1 1 1 -0.770882564020219 -1.51273206980501 0.451800938417985 -3.85955310240754 6.20783927737032 -0.621722459290613 0.534656863659634 16.1087525168232 19.5396398933805 0.824413991492259 0.410442996363399 IL21R-AS1 other 1 1 1 -0.621722459290613 0.824413991492259 3.41161465316815e-05 380.891632022326 92.3448424351915 4.12466600167345 4.9427594556782e-05 -130.493654423639 218.271497551009 -0.597850181483925 0.550439169255289 RBM15B other 0.26559420074914 1 0.477322280634844 4.12466600167345 -0.597850181483925 0.745313699271122 -2.04006791553632 33.5133135721345 -0.0608733574239162 0.951505437924666 -83.5632579813286 111.50829807338 -0.749390488646308 0.454279158733179 LINC00261 other 1 1 1 -0.0608733574239162 -0.749390488646308 0.233177820451593 31.1325397517514 25.7304135190014 1.20995100715193 0.227355944445219 -94.7204490179551 97.6715201099156 -0.969785756496474 0.333021223700508 MIR568 other 1 1 1 1.20995100715193 -0.969785756496474 0.0439041673982647 2.6003487685144 1.68114196117861 1.54677524478144 0.123075867525459 -3.9217941927235 3.87467379445173 -1.0121611265287 0.312357243011935 TGFBR3L other 1 1 1 1.54677524478144 -1.0121611265287 0.000272035221558447 67.7005541078946 24.2456146802301 2.79228037732933 0.00560783878741891 -103.369751012144 53.4359049172104 -1.93446244004471 0.0541009585094307 HOXB7 other 1 1 1 2.79228037732933 -1.93446244004471 6.72026356297218e-15 1520.22463825203 205.793792538915 7.38712581898972 1.92267682894044e-12 -2071.99791125628 845.400843496849 -2.45090589534526 0.0148913975587933 NORAD other 8.85797940235363e-11 1 2.69155529283373e-08 7.38712581898972 -2.45090589534526 2.84690711150953e-11 66.7362827920383 12.8926462199683 5.17630606265113 4.45604524176641e-07 -52.2719355248843 26.8377784453043 -1.94769979308887 0.0524988982953553 MIR762HG other 3.31664678490861e-07 1 0.00505850255845323 5.17630606265113 -1.94769979308887 0.0807784230209894 2.37787679282528 1.60387013398069 1.4825868643888 0.139359137028461 -8.20171495076506 6.52497392302265 -1.25697283200262 0.209857847657791 SPDYE6 other 1 1 1 1.4825868643888 -1.25697283200262 0.83178632723231 2.07923094931402 10.1867107237772 0.204112103081596 0.83842080827641 11.5341921356517 19.1174567907221 0.603332977912073 0.546797466360846 AOC4P other 1 1 1 0.204112103081596 0.603332977912073 0.4606663744681 2.78122229663318 5.29043326054923 0.525707850314029 0.599519525561148 -8.42974426178965 9.96451580472961 -0.845976305019107 0.398309573404585 CCDC187 other 1 1 1 0.525707850314029 -0.845976305019107 8.8278106210558e-05 53.8782953097642 19.1078583884938 2.81969304012679 0.00516179985667175 -64.2763783240942 36.8890008816158 -1.74242665260493 0.0825682221409748 FRRS1L other 0.658642950436974 1 1 2.81969304012679 -1.74242665260493 3.41411057368811e-06 98.1738281455963 20.3715549731935 4.81916222275526 2.39528496964257e-06 8.66921220216648 56.2317133883896 0.154169447804101 0.877590038966401 JHDM1D-AS1 other 0.0290574950926595 1 0.0258331483975951 4.81916222275526 0.154169447804101 2.23914364027757e-14 171.492466218126 20.7726931675736 8.25566838323247 6.61249527660192e-15 -60.9742306025143 68.5295442380539 -0.889751001271883 0.374385854126535 PMF1-BGLAP other 2.9097671605407e-10 1 9.66085559911541e-11 8.25566838323247 -0.889751001271883 0.00696949074139494 60.6268233764912 22.3312257853295 2.71489008079082 0.00705543558912791 7.11365403513452 40.8768875770989 0.174026313077709 0.861974710439723 SNHG19 other 1 1 1 2.71489008079082 0.174026313077709 0.00350897700870313 89.220106788744 45.4340830286303 1.96372636666887 0.0506072222867941 -130.724714042644 90.6215762782162 -1.44253410072352 0.150332637068543 SLX1B-SULT1A4 other 1 1 1 1.96372636666887 -1.44253410072352 0.00926123824763698 8.66250135748791 3.9875908880188 2.17236461832518 0.0307015081943587 -7.06771585398392 7.63912209087129 -0.92520001250272 0.355691118853339 TBC1D3G other 1 1 1 2.17236461832518 -0.92520001250272 0.814178916062221 74.2187936778954 315.206582912095 0.235460798414206 0.814028282512381 -193.243375125604 535.334315693078 -0.360976999719173 0.71839684125409 MRC1 other 1 1 1 0.235460798414206 -0.360976999719173 0.0636823935825813 7.72097876294176 3.27318719550995 2.35885646061831 0.0190439749813769 6.39072231262374 14.8483095517315 0.430400665500574 0.66724756089433 LINC02367 other 1 1 1 2.35885646061831 0.430400665500574 0.00532976486358526 9.17825159464372 3.15509810317726 2.90902257061389 0.00392844178549528 -8.06274211623568 11.9548227179307 -0.674434268618855 0.500614448953824 SCX other 1 1 1 2.90902257061389 -0.674434268618855 4.03923767462428e-06 11.4506060405352 2.68602712019161 4.26302696441813 2.81013778390132e-05 -1.69722190025166 5.41345042854713 -0.313519431396579 0.754133626831731 ATP2A1-AS1 other 0.0342163823417423 1 0.278175539228392 4.26302696441813 -0.313519431396579 2.2389317664384e-05 18.5971912585873 6.77150858797452 2.74638819651119 0.00642613717817287 -17.1106204005898 11.2919145913222 -1.51529842545385 0.130853804383054 C16orf95 other 0.177883128843531 1 1 2.74638819651119 -1.51529842545385 0.260751738416678 -5.67291571854304 23.3263936643004 -0.243197289739008 0.808036546709986 -60.8558167075277 41.8594715784463 -1.45381234909957 0.147155427837985 MT1L other 1 1 1 -0.243197289739008 -1.45381234909957 3.55595543976848e-05 8.19424860228572 2.63696386896414 3.10745577469919 0.00208923215094398 -4.08392740867146 4.33726390983353 -0.941590711003843 0.347247038757895 SNAI3-AS1 other 0.276404416333204 1 1 3.10745577469919 -0.941590711003843 0.00604726342990251 21.0986690790886 14.9723102588751 1.40917925919829 0.159920203353842 -37.7642592771698 22.5210981580537 -1.67683915820353 0.0947185633434037 LINC01963 other 1 1 1 1.40917925919829 -1.67683915820353 8.98384064818026e-05 21.5669941244448 6.73987234391113 3.19991136685676 0.00154139759257616 -14.8592242967308 14.0197819188769 -1.05987556601887 0.290162646998182 FBXL19-AS1 other 0.669924997134802 1 1 3.19991136685676 -1.05987556601887 0.00172963186155902 6.85987837854373 2.19125252781073 3.13057408558812 0.00193841646985944 -1.75750345654541 4.06802007734497 -0.432029199249297 0.666068878123067 ADPGK-AS1 other 1 1 1 3.13057408558812 -0.432029199249297 0.587777703422414 4.82531721635428 5.34254081130307 0.903187712884753 0.367282024814008 -7.73548778514805 24.2072992887411 -0.319551871230256 0.749570732302527 XKR7 other 1 1 1 0.903187712884753 -0.319551871230256 0.00862472906464097 3.12159470227198 2.83509283947815 1.1010555488005 0.271927244236492 -8.91535360061254 5.02905313431336 -1.77276981620712 0.0774796833667804 LINC00622 other 1 1 1 1.1010555488005 -1.77276981620712 2.75768924966956e-05 9.82263302523111 5.14165889022921 1.91040153283938 0.0571291257477427 -21.8799196057502 8.25945455293772 -2.64907560971662 0.00854149206638718 CAPN10-AS1 other 0.216864682594014 1 1 1.91040153283938 -2.64907560971662 4.66527109808421e-08 36.3159920074413 6.58199299001374 5.51747655497966 8.0802698869538e-08 12.2919557653219 11.3515222966343 1.08284646271332 0.279846251428549 LINC01572 other 0.000456123555259694 1 0.000959612851774634 5.51747655497966 1.08284646271332 0.909981752892147 -7.59269029282348 72.4632867481517 -0.104779822080278 0.916629485251771 -67.708740222219 156.067579749667 -0.433842443964495 0.664754512142311 WFDC21P other 1 1 1 -0.104779822080278 -0.433842443964495 3.54047755042713e-09 14.5202693114268 3.13136471675429 4.63704187306464 5.68979492343353e-06 -13.1256823449646 6.3414190117585 -2.06983363197203 0.0394910635481432 LMO7-AS1 other 3.70298546999173e-05 1 0.0595892222331194 4.63704187306464 -2.06983363197203 0.151243611481314 25.8861890785103 60.1936056794974 0.430048819742451 0.667499394420706 -266.518243492627 166.15273536248 -1.60405570760655 0.109857999345909 TMEM178B other 1 1 1 0.430048819742451 -1.60405570760655 8.89695712915487e-05 10.3424333557184 3.43728302292985 3.00889780874163 0.00288777623727178 -6.09858682005318 5.17729934933381 -1.17794749898669 0.239928734854239 RBFADN other 0.66353506269237 1 1 3.00889780874163 -1.17794749898669 0.0165073342630392 312.594316309721 115.819797455443 2.69897136048766 0.00739576234413409 -124.03672836515 438.846939311373 -0.282642345779568 0.777668376574763 EPPK1 other 1 1 1 2.69897136048766 -0.282642345779568 0.275922102784969 -12.7757584440453 8.00401981942525 -1.59616776723108 0.111608237080131 -10.2687012104355 13.3472042476187 -0.769352219380889 0.442349371516129 LINC02188 other 1 1 1 -1.59616776723108 -0.769352219380889 6.13935591352635e-08 16.4723165211767 17.1616457561276 0.959833150925823 0.337997927756741 -136.229625914822 29.8432866767568 -4.56483320320492 7.60050798403469e-06 SPINT1-AS1 other 0.000595701704289462 0.117230235145751 1 0.959833150925823 -4.56483320320492 1.14020795111034e-11 60.0707799261349 19.8713791160687 3.02297991373732 0.00274453074071416 -219.095054166491 44.2806143358879 -4.94787747307566 1.32431865645914e-06 ZNF865 other 1.34966415172931e-07 0.0206858574138918 1 3.02297991373732 -4.94787747307566 0.483516685788027 6.32395034018954 21.7574470087025 0.290656819141515 0.771541137914874 -39.5472455617994 44.9519150197771 -0.879767759491451 0.379782229857789 PYCARD-AS1 other 1 1 1 0.290656819141515 -0.879767759491451 0.00013328115355647 6.1856289079225 1.70054421883507 3.63744079066634 0.000329777038991558 -2.34037622601975 3.12839693251426 -0.748107186046503 0.455046626761848 MANEA-AS1 other 0.972685858655122 1 1 3.63744079066634 -0.748107186046503 0.788199517410417 -287.163906688283 427.182627807982 -0.672227492400189 0.502009492083862 -289.304308311245 943.874689692173 -0.306507115267172 0.759453057363795 PECAM1 other 1 1 1 -0.672227492400189 -0.306507115267172 1.72364116960589e-07 120.345207998162 31.4416096105365 3.82757783360534 0.000161779789526958 -64.8747152298117 51.233254960301 -1.2662618309159 0.206539758391627 VPS9D1-AS1 other 0.00162522125882139 1 1 3.82757783360534 -1.2662618309159 1.46779401135797e-09 17.9648757653309 2.98848999843537 6.01135549215036 5.99402157314961e-09 -1.19857300204088 5.5539350795232 -0.215806087914116 0.829303057872158 TMEM202-AS1 other 1.57215416556552e-05 1 7.51350604194303e-05 6.01135549215036 -0.215806087914116 6.86454778626794e-09 34.1372623528815 6.38798254997969 5.343981779191 1.95067252613123e-07 -11.929249036596 16.0581856139223 -0.742876519390425 0.458209543495502 LINC01003 other 7.06361967206971e-05 1 0.00226668147536449 5.343981779191 -0.742876519390425 0.354279202856294 4.83428063889775 5.29413302801411 0.913139245522726 0.361975018369869 -4.45093748684989 9.56771861578182 -0.465203635849839 0.642156494253621 SMG1P7 other 1 1 1 0.913139245522726 -0.465203635849839 0.578681116769839 -0.150684144487013 2.5351062812737 -0.0594389851029462 0.952646108469675 -5.97035306370704 6.07064897709022 -0.983478551673522 0.32624595298179 TPBGL other 1 1 1 -0.0594389851029462 -0.983478551673522 0.0540951974901894 2.88383998448474 2.03774589655555 1.41521079215979 0.158154790483193 -4.83367824872852 3.94083066075559 -1.22656329714044 0.221051391212398 C15orf65 other 1 1 1 1.41521079215979 -1.22656329714044 0.496220293749524 -35.3478783124556 29.824701698244 -1.18518799182279 0.236989088255889 -32.5120735875553 51.0466994504274 -0.636908437520599 0.52472612496029 HPR other 1 1 1 -1.18518799182279 -0.636908437520599 2.2306886750223e-05 134.165270064476 41.5884543648666 3.22602203215846 0.00141414429687431 -116.703710538592 82.91390258899 -1.40752885697711 0.160451411326498 BOLA2-SMG1P6 other 0.177250522117272 1 1 3.22602203215846 -1.40752885697711 0.0146029789409404 25.1841059762496 64.3772057707914 0.391196009126508 0.695962031444785 -311.802057252276 125.167480215019 -2.4910788067048 0.0133388228012836 DNAAF4-CCPG1 other 1 1 1 0.391196009126508 -2.4910788067048 0.322214381754348 10.7289564177527 7.6945050539831 1.39436602386774 0.164361922177549 -0.7233813632624 24.6970434440153 -0.02929020086563 0.976654941805881 TCF24 other 1 1 1 1.39436602386774 -0.02929020086563 2.33831579679432e-21 260.433743858834 27.7832659835415 9.37376275392214 2.93523033896607e-18 -359.945484909366 106.064558927441 -3.39364523408433 0.00079315664074158 ISY1-RAB43 other 3.47567260035508e-17 1 4.44335168712684e-14 9.37376275392214 -3.39364523408433 0.00126110092920673 47.4881775581721 17.5295044949021 2.70904277824752 0.00717920291505053 -39.9885900643455 32.8327419163866 -1.21794853948483 0.224306797167946 LOXL1-AS1 other 1 1 1 2.70904277824752 -1.21794853948483 0.152374955713405 24.91174248731 20.8797761692132 1.19310390520574 0.233879930733748 -82.7814496859026 73.7453687931092 -1.12253082519858 0.262637724995012 MIA other 1 1 1 1.19310390520574 -1.12253082519858 0.00205708186111546 157.100055423122 181.401466271666 0.866035201655148 0.38723410666405 -825.975860152702 306.929855752066 -2.69108998252654 0.00756300146519887 PCDHGA9 other 1 1 1 0.866035201655148 -2.69108998252654 0.599342021500346 5.6698048847046 7.85296148196991 0.721995758889464 0.470919597900128 -5.82951776699217 16.3132783639 -0.357348022693737 0.721109409963825 GFY other 1 1 1 0.721995758889464 -0.357348022693737 0.0210658293842666 15.9400326810803 5.90573833767766 2.69907533481215 0.00739351410842902 12.1616214906842 14.947760899618 0.81360824355941 0.416588988597172 SNORD3B-2 other 1 1 1 2.69907533481215 0.81360824355941 0.0010223910630196 199.904031197208 178.127805022436 1.12225057268307 0.262745591653677 -812.91085632799 301.39084663787 -2.69719822415419 0.00742926143435887 PCDHGB3 other 1 1 1 1.12225057268307 -2.69719822415419 0.000451196335244903 55.5689381933436 36.2192526166341 1.53423757197637 0.126133534934279 -167.268154856238 70.0147289016384 -2.38904238408504 0.0175741367421323 CORO7 other 1 1 1 1.53423757197637 -2.38904238408504 0.557486790298713 155.954202432715 232.304103043001 0.671336409429872 0.502578071758861 523.34440564688 508.092709515091 1.03001754570804 0.303920169256366 MMP12 other 1 1 1 0.671336409429872 1.03001754570804 0.00562393118620248 4.76832186108147 5.21723143563082 0.913956361704881 0.361552204070242 -20.9644745463246 9.57584862344061 -2.18930722181696 0.0294275155929147 LINC01569 other 1 1 1 0.913956361704881 -2.18930722181696 0.00127960489668566 197.618829169924 178.074998012096 1.10975056226872 0.268086678552888 -797.576628211774 301.301497591252 -2.64710475914651 0.00859191031557462 PCDHGA4 other 1 1 1 1.10975056226872 -2.64710475914651 0.113558052965385 -253.405067206986 123.136883336592 -2.05791360265558 0.0405877090805918 -303.769702997633 200.487089472558 -1.5151584263944 0.130937773703491 SPON1 other 1 1 1 -2.05791360265558 -1.5151584263944 8.14775213767135e-22 281.642879703751 28.7415269581632 9.79916203177781 1.29989682073312e-19 -163.832138737482 89.1376532100031 -1.8379678265873 0.0671576375094888 OVCA2 other 1.21711121432535e-17 1 1.98663231112643e-15 9.79916203177781 -1.8379678265873 1.30930109785353e-14 634.077241543585 78.4634422518642 8.08118052618983 2.18408655719964e-14 79.7085341172228 174.201445013701 0.457565286619487 0.647634134148771 MRPL12 essential 1.71112560478477e-10 1 3.16583346466087e-10 8.08118052618983 0.457565286619487 2.4439641363511e-12 143.870349518061 18.7270820795224 7.68247551365089 2.81011861648683e-13 128.21166522405 56.1023433473216 2.28531746758437 0.0230611098558629 ALOX12P2 other 2.96795004718478e-08 1 4.00694813524857e-09 7.68247551365089 2.28531746758437 1.48713921288855e-10 699.127438943936 119.53153483227 5.84889535573159 1.42670831010751e-08 -769.699871918232 402.362325169284 -1.91295214231203 0.0568119113679114 GTF2I other 1.6771956042957e-06 1 0.000175898867553155 5.84889535573159 -1.91295214231203 1.63046778996783e-11 30.1969209647937 5.85792691058469 5.15488182521206 4.87728173497047e-07 -51.6332740399076 16.0917494761048 -3.20867995842091 0.00149254234008807 ZNF234 other 1.91954972912913e-07 1 0.00551523018590461 5.15488182521206 -3.20867995842091 0.84118594443143 15.8984727903571 45.0471204386197 0.352929835149396 0.724414389186317 -25.1459065062039 87.3712834426221 -0.287805163383202 0.773715049384439 MYZAP other 1 1 1 0.352929835149396 -0.287805163383202 0.554956471811135 9.78848663735123 9.9471288126645 0.98405146064749 0.325977754849399 4.56036641510416 14.633443675922 0.311640001909314 0.755556424646109 TAPT1-AS1 other 1 1 1 0.98405146064749 0.311640001909314 0.105704802095863 10.0309821011817 4.89491240248177 2.04926692786083 0.0415807925108574 5.15763715264134 8.77755517660136 0.587593817284138 0.557386442573433 PPIAL4A other 1 1 1 2.04926692786083 0.587593817284138 0.0682306904239538 6.86830175701867 3.22017743407691 2.13289543747999 0.0338885142667384 -9.27760409067855 10.9078519265108 -0.85054364078137 0.39582083301712 PPIAL4C other 1 1 1 2.13289543747999 -0.85054364078137 4.84315120794124e-13 209.2141354989 48.7384834033711 4.29258608166764 2.47009654421549e-05 -304.481283162935 86.9399742577632 -3.50220121138059 0.000540421757635509 SRSF8 other 6.03505072021558e-09 1 0.245576998425904 4.29258608166764 -3.50220121138059 0.0654026234080578 19.3485135694443 8.38725573067851 2.30689443493087 0.0218886631806841 -10.6950679802112 28.2807337389471 -0.378175052986067 0.705625363301044 FAM72C other 1 1 1 2.30689443493087 -0.378175052986067 0.260923951678955 36.804209119968 43.2749902677783 0.850472961223788 0.395807474966151 -160.752759464589 122.362086322049 -1.31374647406304 0.190034464565548 IKBKE other 1 1 1 0.850472961223788 -1.31374647406304 0.389326724286389 -104.047404874059 86.6978799032818 -1.20011475471064 0.231142842821859 -171.51061926831 136.276598186262 -1.25854784717982 0.20927683872315 MSMB other 1 1 1 -1.20011475471064 -1.25854784717982 5.18336742234245e-11 239.563411134986 40.4522196822258 5.92213265469453 9.74760006095179e-09 -120.358955017435 88.8431608044342 -1.35473517519682 0.176647141717618 LINC00667 other 5.97486762773414e-07 1 0.000121104183157265 5.92213265469453 -1.35473517519682 1.03250770269421e-09 3.0557386008559 0.482119391315236 6.33813668543751 9.90434446557175e-10 -6.39371328500177 4.22504658157246 -1.5132882351849 0.131393679519681 SNORA4 other 1.11366280812598e-05 1 1.28003747873049e-05 6.33813668543751 -1.5132882351849 0.00471554654123648 5.12796014028758 3.82233328630045 1.34157849569701 0.180876896953084 -10.8107060155684 5.87394349838398 -1.84045114130611 0.0668158874886335 LINC00908 other 1 1 1 1.34157849569701 -1.84045114130611 0.541647758242854 -3.44651317245959 3.83000288278797 -0.899872213660261 0.369008345902852 -7.35935576710206 7.3292162229157 -1.00411224655811 0.31624395581486 LINC00672 other 1 1 1 -0.899872213660261 -1.00411224655811 0.0249351597441024 56.8555217066421 21.0702696780026 2.69837655499965 0.00740863567530401 56.3630330177444 53.3300554865259 1.05687182403147 0.291518289025048 SNORD3A other 1 1 1 2.69837655499965 1.05687182403147 0.000905577047871625 68.0583025876251 17.9506887910025 3.79140340407096 0.000187365007189111 16.9945069053197 60.8569266809538 0.279253452847109 0.780278468215158 NBPF11 other 1 1 1 3.79140340407096 0.279253452847109 0.917628582904773 -1.87391324899752 7.39711432340932 -0.253330307883337 0.800203643326014 -7.36379357706524 20.9156913906695 -0.352070292084641 0.725057165345026 C1orf186 other 1 1 1 -0.253330307883337 -0.352070292084641 2.17406399942097e-20 71.7993534898354 11.8027809383979 6.08325731576115 4.04818984511193e-09 -68.2607303433507 18.2027606737755 -3.75002075601056 0.000216671617307096 LINC00909 other 3.19391742154935e-16 1 5.11205413640735e-05 6.08325731576115 -3.75002075601056 6.99562377730443e-13 844.497214083287 120.005092088518 7.03717816790951 1.59548229909937e-11 -375.444984149095 257.468448638472 -1.45821744813588 0.14593429629488 DYNLL2 other 8.67527304623522e-09 1 2.18309842985767e-07 7.03717816790951 -1.45821744813588 5.88076719389878e-10 261.98751314578 39.3151821988392 6.6637746156373 1.56722531502101e-10 -150.225761590688 133.289323957136 -1.12706522271055 0.2607460707257 OTUD7B other 6.43708777044161e-06 1 2.08362605632043e-06 6.6637746156373 -1.12706522271055 0.257747832406809 1.12551353310778 1.83224711451201 0.614280423308262 0.53954161351634 -5.08671970851767 3.90200386188837 -1.30361729218175 0.193462338877211 SEPT4-AS1 other 1 1 1 0.614280423308262 -1.30361729218175 9.79195297043592e-14 88.0936696936051 14.049155259013 6.27038907816826 1.44894625138871e-09 -56.6690535129574 27.0812044059427 -2.0925603109632 0.0373361298223191 DSG2-AS1 other 1.24847400373058e-09 1 1.86160614378421e-05 6.27038907816826 -2.0925603109632 0.0494127001518713 26.0172265328984 10.7510027731854 2.41998138050798 0.0161794268761481 25.6734057827438 27.7073073879529 0.926593314293199 0.354962175278879 SNORD3C other 1 1 1 2.41998138050798 0.926593314293199 6.13635124953101e-06 14.4761437178991 7.60849887813766 1.90262809389313 0.0581411898208032 -32.9297714683463 12.4974470838798 -2.63491985581772 0.00889658849792312 AGAP12P other 0.0511096695573438 1 1 1.90262809389313 -2.63491985581772 0.391931529301641 -46.6165116916786 58.7293636850542 -0.79375134969395 0.428084025957164 218.663836815077 199.105929661701 1.09822865238924 0.273148712811299 GJA5 other 1 1 1 -0.79375134969395 1.09822865238924 1.7419162316774e-09 55.7398954809085 10.0159395783733 5.56511898307208 6.25382847310142e-08 -39.7764676357958 21.3302204739246 -1.86479402237877 0.0632831978124938 TSPOAP1-AS1 other 1.85810204433028e-05 1 0.000747144887681427 5.56511898307208 -1.86479402237877 0.0439797691292083 15.8300912278397 6.42187539636775 2.46502621909999 0.0143253150519569 14.5623403923371 16.2541332621574 0.895916143756552 0.371098567081952 SNORD3B-1 other 1 1 1 2.46502621909999 0.895916143756552 0.291364254707249 -7.17792411793134 4.57232904891449 -1.56986167030902 0.117605577799303 -5.28267836561697 9.73735773159638 -0.542516616029769 0.587905257398528 MIR142 other 1 1 1 -1.56986167030902 -0.542516616029769 7.55098400228098e-12 423.002192948035 58.8421207706285 7.18876524856969 7.40821979183314e-12 -413.522649894875 199.241484185653 -2.0754846892706 0.0389561259768256 RBM8A essential 8.99397704511687e-08 1 1.02218616687714e-07 7.18876524856969 -2.0754846892706 2.00866729087016e-15 383.570489171241 61.9764523997264 6.18897136443606 2.22965686549699e-09 -122.254440663043 97.4180696241895 -1.25494624492833 0.210579416825489 TIMM23 essential 2.68639163480976e-11 1 2.84348140056831e-05 6.18897136443606 -1.25494624492833 5.03804121070607e-05 70.9156069927644 23.579015278897 3.00757288436185 0.00288175805285894 -180.757130168908 79.1334564009102 -2.28420618016666 0.0231358170239588 DTX2P1-UPK3BP1-PMS2P11 other 0.385712435091657 1 1 3.00757288436185 -2.28420618016666 0.266683456879148 6.57659963436925 4.03729620645739 1.6289613885279 0.104555920009104 7.08822754134596 9.41437727876653 0.752915177654178 0.452195404543609 KRT18P55 other 1 1 1 1.6289613885279 0.752915177654178 9.40599138742945e-14 200.788052445549 24.391212647087 8.23198318799164 1.04009245145237e-14 -4.11117179417151 82.3299893251257 -0.0499352888038921 0.960213988117396 RNF115 other 1.20011044112212e-09 1 1.51531069252096e-10 8.23198318799164 -0.0499352888038921 1.34954262475573e-08 24.3489542547172 5.08630374768529 4.78716086623771 2.8000970276268e-06 -8.90983555019517 8.02732126587174 -1.10993882705 0.268020299947468 MIR1539 other 0.000136330795952824 1 0.0300618416886013 4.78716086623771 -1.10993882705 0.0376851620872585 14.4837993146836 6.976465552933 2.07609414893398 0.0389198190696227 37.2284586611031 23.5237330393733 1.58259144493739 0.11479418607483 FCGR1CP other 1 1 1 2.07609414893398 1.58259144493739 0.537964209520475 3.98968302612632 3.80317441076992 1.04904024775415 0.295111781425787 0.743606456081612 8.4647944642062 0.0878469594537692 0.930064410782086 RARA-AS1 other 1 1 1 1.04904024775415 0.0878469594537692 1.27765087476179e-12 1050.38376907491 206.394352118728 5.08920790851233 6.74543898140901e-07 -844.423010287485 326.434309717226 -2.58680838732597 0.0102104994383165 RPL17 essential 1.56767762333271e-08 1 0.00756770799324277 5.08920790851233 -2.58680838732597 1.04033141260791e-10 70.5963814156343 11.7870714159557 5.9893063276151 6.78335682808776e-09 -35.3862965546568 26.2119230479707 -1.35000764689779 0.178156864200546 MAFG-AS1 other 1.18233665042889e-06 1 8.47987437079251e-05 5.9893063276151 -1.35000764689779 8.28422702868833e-05 23.6464752927169 15.4310457338035 1.53239616424158 0.126582688827079 -62.0951849455256 25.3464816905306 -2.44985421265486 0.0149197456847339 ZNF488 other 0.620074393097321 1 1 1.53239616424158 -2.44985421265486 0.451321695356306 -7.62845004218391 8.62831357641211 -0.884118312880792 0.37865231397563 -23.354013498855 19.1238893224064 -1.22119580934263 0.224746876477098 CYP4F35P other 1 1 1 -0.884118312880792 -1.22119580934263 2.98152786748759e-11 177.032906224858 47.7898005887 3.70440771972415 0.000263702581612833 -279.323048958551 85.1894902601551 -3.27884399948331 0.00119890324826435 SEC22B other 3.46930582660856e-07 1 1 3.70440771972415 -3.27884399948331 2.22616862097788e-07 37.2878573651457 7.12306018660894 5.23480869012525 3.33127348405263e-07 -18.2140944004443 25.6776738035219 -0.709335843262645 0.478730439546713 FSBP other 0.0020841390629595 1 0.0038163069033307 5.23480869012525 -0.709335843262645 0.0017694299667461 114.907205635139 33.9332046619999 3.38627626773541 0.000814272688220535 16.8827077059049 74.5615347800681 0.226426504707867 0.821041674628357 LINC00668 other 1 1 1 3.38627626773541 0.226426504707867 0.738317521293297 573.270254773894 777.941046593434 0.736907066781238 0.46186166108807 -621.465697761379 2637.39747181017 -0.235635964773576 0.813905791796325 TXNIP other 1 1 1 0.736907066781238 -0.235635964773576 0.0181670146780263 256.908962152804 93.2080053120896 2.75629717954581 0.00624129513969427 35.3460539774939 234.80563336453 0.150533245182495 0.880455494524226 ESRG other 1 1 1 2.75629717954581 0.150533245182495 0.000744968884963753 128.493050055653 33.6246163247908 3.82139825223573 0.000164371296506798 -4.60628933173512 95.0751965470303 -0.0484489067498961 0.961393908085988 SRGAP2 other 1 1 1 3.82139825223573 -0.0484489067498961 2.15937892030592e-10 6.60169509474897 1.23623718549551 5.34015249840821 1.98298174191317e-07 -5.24664176795525 2.6902507396096 -1.95024266352088 0.0521896575510737 NDUFV2-AS1 other 2.41807251495857e-06 1 0.00230362988958053 5.34015249840821 -1.95024266352088 0.509547826006757 21.1563900746388 30.3446933707199 0.697202302101787 0.486282811340184 -42.3874088216386 67.4401332151616 -0.628519055358409 0.530201253235947 BAHCC1 other 1 1 1 0.697202302101787 -0.628519055358409 0.00658596417858524 -152.594787697818 56.0275396233878 -2.72356752988881 0.00687450012007277 -307.698918689442 158.420524126925 -1.94229201288917 0.0531300865601915 RASSF5 other 1 1 1 -2.72356752988881 -1.94229201288917 4.43946115438546e-09 109.633792519624 22.0079752820782 4.98154833029565 1.12292924730667e-06 -135.893876661024 48.75522958273 -2.78726770079983 0.00568999964579574 STRADA other 4.61659565444545e-05 1 0.0123993847487602 4.98154833029565 -2.78726770079983 0.0104825942109021 53.6408693474703 17.7473453387469 3.02247284445178 0.00277109287270637 28.0570971496186 59.8417365840401 0.468854995713836 0.639586828201586 NBPF15 other 1 1 1 3.02247284445178 0.468854995713836 1.58291530017132e-08 8.21669368743402 1.34307484779129 6.1178226224298 3.29158969752126e-09 1.30761127838253 2.9675700102725 0.440633674641581 0.659828208814258 SNHG25 other 0.000159225450044233 1 4.17208994160819e-05 6.1178226224298 0.440633674641581 1.69091244005528e-08 318.876075390158 257.504515691572 1.23833197462096 0.216664622259481 -1661.50393229679 404.760063973837 -4.10491073646086 5.35754311228083e-05 NCOA4 other 0.000169852154603553 0.807917501331949 1 1.23833197462096 -4.10491073646086 9.85577014262743e-05 220.879467699994 51.1062451903605 4.32196626610431 2.19540617261727e-05 -93.2088738518912 173.473588345319 -0.537308732360734 0.591508676217989 MRPS21 essential 0.731101029180103 1 0.219145444150656 4.32196626610431 -0.537308732360734 0.0688250126857472 17.7564302822035 22.3973606280659 0.792791194331759 0.42858791013769 -47.2185905446215 36.7478123226095 -1.28493609715019 0.199903731220055 GDF10 other 1 1 1 0.792791194331759 -1.28493609715019 0.845183707945291 -23.5949079459261 40.8719002846762 -0.577289232494345 0.564223361548309 -8.15622204767816 94.6562869317151 -0.0861667229094043 0.931397511582179 MYO15B other 1 1 1 -0.577289232494345 -0.0861667229094043 0.0205113961053 15.9389631581792 5.84880502728544 2.72516575331574 0.00685006210149132 6.46494629090998 11.6283825212025 0.555962643912186 0.57870024238088 DSG1-AS1 other 1 1 1 2.72516575331574 0.555962643912186 1.03588614495812e-17 32.6764496096921 4.6905541598728 6.96643690616255 2.43123308933972e-11 -16.6477300859908 7.51533448682957 -2.2151682157548 0.0275740061485275 MIR3661 other 1.45997793270397e-13 1 3.30842198797349e-07 6.96643690616255 -2.2151682157548 0.735978211711712 0.426372182108119 3.2746206947661 0.13020505941027 0.896500786831775 5.44689581112814 7.17679618706987 0.758959244368898 0.448536545083492 MIR4444-2 other 1 1 1 0.13020505941027 0.758959244368898 0.0403687925659743 3.45902681411125 2.38048032294118 1.45307935578206 0.147393829469915 -6.97363580731075 5.14186710937805 -1.35624582646094 0.17618415618702 GAPLINC other 1 1 1 1.45307935578206 -1.35624582646094 0.454093118116039 5.96203412285356 9.53363501727605 0.625368404816176 0.532253615020835 47.4314830934517 39.3474491266616 1.20545255527918 0.229076276489818 FXYD1 other 1 1 1 0.625368404816176 1.20545255527918 4.78201580877419e-09 119.378541900817 24.3705406205605 4.89847737723558 1.67270970121879e-06 -71.955286674511 45.7363294112808 -1.57326325922349 0.116837643933515 AARSD1 other 4.96229780476498e-05 1 0.0182526082596994 4.89847737723558 -1.57326325922349 0.622946123829552 -7.37443639898765 7.63893844526673 -0.965374502206786 0.33523082808042 -8.08609476877695 12.7602353587384 -0.633694798053977 0.526822490478917 LINC01929 other 1 1 1 -0.965374502206786 -0.633694798053977 1.52519577320222e-06 27.4488633268219 5.28793721622022 5.19084516408881 4.12171513166751e-07 3.47902408440723 21.3779103747614 0.162739202448642 0.870845511106522 ZNF850 other 0.0133866433013959 1 0.0046921605058903 5.19084516408881 0.162739202448642 7.88580423316751e-05 9.26432139516354 2.77746501981132 3.33553125928942 0.000971673230458167 -5.97517168783272 5.21248408282041 -1.14631941179946 0.252685477030672 PTGES3L other 0.591514175529895 1 1 3.33553125928942 -1.14631941179946 2.42983888202052e-08 45.02633854235 10.2063966465227 4.4115803159277 1.48012939042819e-05 -46.0438372174636 21.1130887673734 -2.18081957238849 0.0300535537959317 ASB16-AS1 other 0.000241817565538682 1 0.149892703368662 4.4115803159277 -2.18081957238849 1.67275258131409e-06 135.856954000541 35.0807646127142 3.87269078939353 0.000135110615851649 -101.179160532404 71.9055009732686 -1.40711293521226 0.160543983003648 ILF3-AS1 other 0.0146382578390796 1 1 3.87269078939353 -1.40711293521226 2.32809901946001e-11 53.1128118847323 8.82336933983949 6.01956121738167 5.80366967578117e-09 -43.1956582883735 19.0681354262188 -2.26533204861652 0.024299777333466 TBC1D3P1-DHX40P1 other 2.72108213394486e-07 1 7.27838214039716e-05 6.01956121738167 -2.26533204861652 0.478249689912679 7.27902015303778 6.74302435422221 1.0794889311767 0.281326112064218 0.533873201620075 13.4131537084182 0.0398022130533712 0.968280010406773 ZNF561-AS1 other 1 1 1 1.0794889311767 0.0398022130533712 0.937777802841258 -3.77491720390644 12.7843514506719 -0.295276394619772 0.768008845263581 3.74797745747283 37.2834545332603 0.100526560759795 0.920000626718253 PCAT19 other 1 1 1 -0.295276394619772 0.100526560759795 0.0529324100160579 6.16186143405509 2.6900466977455 2.29061504367909 0.0227481143228208 8.4822327493054 5.86621618791631 1.44594615636187 0.149339333558865 LINC02081 other 1 1 1 2.29061504367909 1.44594615636187 0.0220976587339699 6.00860936199128 3.50835734625455 1.712656029297 0.0879196419769586 -13.7242287683034 8.04155546079761 -1.70666344778802 0.089030135324444 RNF157-AS1 other 1 1 1 1.712656029297 -1.70666344778802 3.71252375823302e-12 237.191875217722 35.6018209999983 6.66235233354309 1.62997643915419e-10 -66.8392254370866 80.0451682782408 -0.835018863409098 0.40448264631 CHMP1B-AS1 other 4.4769324000532e-08 1 2.16607568999201e-06 6.66235233354309 -0.835018863409098 0.000135003929974285 4.41678993601159 3.19807156280025 1.38107914387764 0.168487872948216 -13.2978751776164 4.83663110852019 -2.74940860265131 0.00640607958808928 PARD6G-AS1 other 0.984232044072691 1 1 1.38107914387764 -2.74940860265131 0.199738625873216 5.26952793138222 7.84506052673579 0.671700098861416 0.502342638572048 -15.6870727357113 14.2125420744909 -1.10374855205297 0.270674164270909 LINC01140 other 1 1 1 0.671700098861416 -1.10374855205297 0.000389824366094403 15.7391255263149 6.63512242240888 2.37209270972288 0.018386371100781 -29.7949304684727 13.9669847725755 -2.13323999085155 0.0338034135750778 MAP3K14-AS1 other 1 1 1 2.37209270972288 -2.13323999085155 0.00387382376952336 8.31258847257195 2.78058050238543 2.98951548622335 0.00305879701854521 -3.96218906719117 5.96753204621849 -0.663957736046333 0.507298997785584 TBX2-AS1 other 1 1 1 2.98951548622335 -0.663957736046333 7.13163819593483e-06 26.1114718563553 6.3314588764524 4.12408456974547 4.985425248607e-05 -34.0931711595011 21.2383107511495 -1.6052675544196 0.109625932841122 CEBPA-AS1 other 0.0590784908151242 1 0.481243099248033 4.12408456974547 -1.6052675544196 0.926180839570991 -1.71320698530195 9.46686084634717 -0.180968856847938 0.856527788867005 4.96896182327867 21.9632023122448 0.226240315625941 0.821185691318197 LINC01764 other 1 1 1 -0.180968856847938 0.226240315625941 0.00804788365065796 12.5638862176858 4.15699262056792 3.02234989677932 0.00274823089112966 -0.318471996883577 8.93498848354066 -0.0356432464876973 0.971593064398638 KCNJ2-AS1 other 1 1 1 3.02234989677932 -0.0356432464876973 9.99907899621885e-11 22.4425655651509 3.96486838256718 5.66035575451303 3.81781762342653e-08 -20.2544326184634 10.5973787652736 -1.91126816046577 0.0570172134641972 DM1-AS other 1.13779519897974e-06 1 0.000460619696266411 5.66035575451303 -1.91126816046577 0.515997003112236 0.973286548218154 1.68366528779792 0.578076031662519 0.563689310930468 -2.59458976988727 3.84069084239392 -0.675552882634534 0.499896379029088 ZNF582-AS1 other 1 1 1 0.578076031662519 -0.675552882634534 0.00485059524166597 6.95655907478644 2.1370372535913 3.255235285719 0.00127863190524284 2.11113436663541 10.4979130412485 0.201100386175835 0.840772620323232 ZNF571-AS1 other 1 1 1 3.255235285719 0.201100386175835 0.0314858542577382 7.35862454894545 3.31390247317438 2.22053141530645 0.0272067975488617 -6.04308605223255 9.55183740554454 -0.632662156573637 0.527485776310863 ZNF285 other 1 1 1 2.22053141530645 -0.632662156573637 0.49452627801662 19.3731700785527 16.512410585699 1.17324905276589 0.241718565950235 13.2680562167739 35.0548560357761 0.378494100880998 0.705357738550301 S1PR2 other 1 1 1 1.17324905276589 0.378494100880998 1.01624171931104e-09 64.0672105631928 15.9036203919136 4.0284670398552 7.28331141288961e-05 -159.197210537338 43.6873110600488 -3.64401485636228 0.000321227618869894 ZNF224 other 1.09733780851207e-05 1 0.693516912735349 4.0284670398552 -3.64401485636228 3.18908866487496e-15 103.342028689235 13.7239404515524 7.53005516557345 7.4315362690765e-13 -37.3331838977815 37.3930819370376 -0.998398151846458 0.318970438194996 LUZP6 other 4.24180683315019e-11 1 1.04948155191898e-08 7.53005516557345 -0.998398151846458 0.00322597170076147 2.87225940004749 1.20114258786962 2.39127263411899 0.0174674701572328 -4.66139543246788 3.33324759516341 -1.3984546000218 0.163111525630391 EML2-AS1 other 1 1 1 2.39127263411899 -1.3984546000218 0.00193470188340862 44.2225688863375 49.9679734161892 0.88501825995628 0.376925604438396 -247.700570863632 96.901435925057 -2.55621156176883 0.0111236659154549 SMIM22 other 1 1 1 0.88501825995628 -2.55621156176883 4.71408970354432e-17 53.47374958224 6.2159455671275 8.60267339936684 6.57108697913563e-16 -34.4061370500569 24.8689295167317 -1.38349891686768 0.167658968228255 LIN37 other 6.55871300454121e-13 1 9.72060896823534e-12 8.60267339936684 -1.38349891686768 3.10624975267173e-05 10.7306404762329 4.93128626711436 2.1760327620388 0.0304603772178572 -35.3307881231577 11.9378219468062 -2.95956735496544 0.00336716000432639 MZF1-AS1 other 0.242939793156456 1 1 2.1760327620388 -2.95956735496544 0.281997171133217 6.33200363147898 6.08474900147597 1.04063514040481 0.298972423493463 -6.23557368645928 11.16943494431 -0.558271185386675 0.577120152370777 CCDC177 other 1 1 1 1.04063514040481 -0.558271185386675 0.0711421523341442 -0.250145828191974 5.44116953069086 -0.0459728054384318 0.963365659215589 -23.9798906662479 11.3318529495808 -2.11614912167872 0.0352406265919784 CARD8-AS1 other 1 1 1 -0.0459728054384318 -2.11614912167872 1.71800488234824e-08 43.4530000481741 11.2326747165713 3.86844639808442 0.000137136581973421 -69.1896959405209 23.4876478671908 -2.94579075485757 0.00350014357521801 PTOV1-AS1 other 0.00017252205028541 1 1 3.86844639808442 -2.94579075485757 0.00214189682851718 70.278300593309 19.8139464829043 3.54691079104034 0.000464350788774403 -2.36368724136216 67.1737949674025 -0.0351876389075411 0.971957864976715 NBPF12 other 1 1 1 3.54691079104034 -0.0351876389075411 5.44876941204403e-16 31.1748403062525 5.41281185267329 5.75945389471754 2.26965703111502e-08 -41.8020521707861 11.1923345737602 -3.73488228888267 0.000228624483603284 NAPA-AS1 other 7.3879864457905e-12 1 0.000276807371514787 5.75945389471754 -3.73488228888267 0.539964198329874 -41.796409926689 47.6295627773887 -0.877530833571521 0.380969975354561 3.3383632739064 79.4252784171932 0.0420314960228549 0.966504313917104 FENDRR other 1 1 1 -0.877530833571521 0.0420314960228549 0.623848803557407 -1.34661397737125 1.43084065717713 -0.941134829106658 0.347467788796079 -2.0893040229232 3.17037880078277 -0.659007694098682 0.510446285283653 ADGRE4P other 1 1 1 -0.941134829106658 -0.659007694098682 0.00168668774035088 15.2623362618774 6.34326605267002 2.40606907153976 0.0168077799996221 -24.5856238772047 15.3302297139951 -1.60373486476593 0.109959175042954 A1BG-AS1 other 1 1 1 2.40606907153976 -1.60373486476593 3.10742067046175e-05 15.1174752158481 4.79356536672615 3.15370169368793 0.00179419125048894 -17.7546600123536 9.02434467625177 -1.96741820589768 0.0501585971027653 MAN1B1-AS1 other 0.242969222223404 1 1 3.15370169368793 -1.96741820589768 0.491033703693464 -43.3827955975918 87.4450854751752 -0.496114737173054 0.620212643694899 -163.268419395782 137.240983931391 -1.18964768918738 0.235218491334866 MTRNR2L2 other 1 1 1 -0.496114737173054 -1.18964768918738 0.116473169965578 -7.17387091154069 9.24190431904122 -0.776232977954583 0.438295936712302 -32.4465084186027 15.8315999555323 -2.04947753289233 0.0413888257666909 TRABD2B other 1 1 1 -0.776232977954583 -2.04947753289233 7.80840765130075e-10 121.985686303997 18.8412013876808 6.47441125403797 4.5440507677277e-10 -56.2095703153567 95.1434893668218 -0.590787353810864 0.555162661969679 FBXO17 other 8.49398584308495e-06 1 5.94225518895751e-06 6.47441125403797 -0.590787353810864 5.61662736199607e-05 30.534387688066 7.02062873168251 4.34923834531674 1.93347424614008e-05 6.44225819305777 12.7324324721139 0.505972303969989 0.613285909435916 ZSCAN16-AS1 other 0.42809933753134 1 0.19392746688785 4.34923834531674 0.505972303969989 4.10121001745557e-07 35.6279136648039 8.98335868479613 3.96599032888471 9.36882174056901e-05 -45.5724285280862 21.7974600852893 -2.09072196254839 0.0374880422668188 ZNF587B other 0.00377229297405563 1 0.881137684700515 3.96599032888471 -2.09072196254839 5.27847173420768e-33 59.802801337208 5.38442658227236 11.1066239688553 6.99093248471201e-24 -29.6789853578743 12.3875091877351 -2.39587998750059 0.0172565217255243 RAB11B-AS1 other 8.31781575876446e-29 1 1.0888377344939e-19 11.1066239688553 -2.39587998750059 0.278914810707644 11.0047460850966 218.964086657177 0.0502582238626477 0.95995377355619 -687.219858202102 469.513750814388 -1.46368419883357 0.144443474263873 SPIB other 1 1 1 0.0502582238626477 -1.46368419883357 0.0667558345266019 32.9008811491279 14.5406209854198 2.26268748646418 0.024470899390652 18.238744347598 29.9714606185608 0.608537053956692 0.54335654959652 LINC01224 other 1 1 1 2.26268748646418 0.608537053956692 0.0267134260108728 0.0476178538400693 1.43640063023636 0.0331508165881505 0.973578543454618 -7.31656595593487 2.98982237937272 -2.44715739851741 0.0150293754698428 PLA2G4C-AS1 other 1 1 1 0.0331508165881505 -2.44715739851741 9.45376779694113e-07 72.9188319402149 29.7686941641568 2.44951396047507 0.0149335383130716 -99.9294909177302 41.9153681922175 -2.38407761228457 0.0178054453310124 RPARP-AS1 other 0.00842803399097302 1 1 2.44951396047507 -2.38407761228457 0.391132659358467 25.0374346407989 19.506854267445 1.28351984884534 0.200402407346244 14.3984202254405 28.3697730923757 0.507526802507632 0.612196502277711 KCNQ1OT1 other 1 1 1 1.28351984884534 0.507526802507632 0.223732660266455 22.4529676232407 14.5965539819671 1.53823756285076 0.125157289815309 -5.25195205456085 33.7060379950525 -0.155816357156298 0.876293778891858 ZNF528-AS1 other 1 1 1 1.53823756285076 -0.155816357156298 2.16529121448911e-30 475.48604082856 41.6948165873443 11.4039604858913 7.50305645411964e-25 -474.893944658427 147.158726163467 -3.22708654144577 0.00140484665912984 EGLN2 other 3.39496009519747e-26 1 1.17220250982711e-20 11.4039604858913 -3.22708654144577 2.37815724500171e-12 51.9836522721557 7.3898827645978 7.03443531217981 1.61115320765002e-11 9.58172544459701 11.5933267301322 0.826486276772753 0.409250046072185 ARHGAP19-SLIT1 other 2.88946105267708e-08 1 2.20405758806523e-07 7.03443531217981 0.826486276772753 8.4365859010659e-13 223.814849786187 42.887107432692 5.21869772022855 3.60530254931893e-07 -107.204959688768 62.8548451223508 -1.70559579742957 0.0892376884433499 SNHG8 other 1.04284638323076e-08 1 0.00411977922310674 5.21869772022855 -1.70559579742957 1.11116227884176e-10 240.889058284416 55.1965377119684 4.36420594968194 1.81835919894924e-05 -203.877098830099 92.3482717615829 -2.20769804286595 0.0281062523321898 COMMD3-BMI1 other 1.26128030271328e-06 1 0.182817833862357 4.36420594968194 -2.20769804286595 0.0368423385281434 11.2494703799632 5.85388996258883 1.92170854796666 0.0557148012865781 -8.56806768820393 16.39577415052 -0.522577806302132 0.601704688120729 RMRP other 1 1 1 1.92170854796666 -0.522577806302132 3.21986296915142e-22 396.471645253703 45.0193322833386 8.80669759290134 1.5209876372037e-16 -335.950155544229 124.267106424843 -2.70345198507872 0.00729294391339052 C7orf55-LUC7L2 other 4.83043842632096e-18 1 2.26794466583443e-12 8.80669759290134 -2.70345198507872 0.000548705817453878 5.13528999298807 2.77532310498065 1.85033950957717 0.0653489643987218 -9.58047148237114 4.88278113602299 -1.96209316278599 0.0507711462105149 MKNK1-AS1 other 1 1 1 1.85033950957717 -1.96209316278599 1.02989358744365e-06 43.3988845449629 11.1818461384017 3.88119135318082 0.000130931315768581 -74.4406236155356 35.890357849781 -2.07411204778472 0.0390237299383425 C8orf44-SGK3 other 0.00915781377954898 1 1 3.88119135318082 -2.07411204778472 0.000168492315417476 11.511253651732 2.9855823092525 3.85561423513862 0.000144482613557254 -13.336928840754 9.56403845868818 -1.39448716129308 0.164321112034545 GAS5-AS1 other 1 1 1 3.85561423513862 -1.39448716129308 3.70164823808076e-09 78.5526437268974 12.5119119075452 6.27822864381959 1.35440266570726e-09 -29.2454889261986 35.5425974966195 -0.822829252391589 0.411328537316521 TSNAX-DISC1 other 3.86748207914678e-05 1 1.74257446969896e-05 6.27822864381959 -0.822829252391589 0.00114367258134225 -2.09162136220932 0.997209294983967 -2.09747479564252 0.0368779580087428 -10.4200165220738 2.90819659903243 -3.5829821565504 0.000402633961359483 LINC01480 other 1 1 1 -2.09747479564252 -3.5829821565504 6.25658969042915e-23 177.106591818213 28.6250279118892 6.18712381218858 2.2626390518777e-09 -296.64701851646 52.0918674280189 -5.69468965431831 3.22209312013459e-08 BIVM-ERCC5 other 9.44119384285759e-19 0.000510830643266138 2.88463852723887e-05 6.18712381218858 -5.69468965431831 0.00713775500297306 79.6072671407379 28.3318904908456 2.80981133844422 0.00538772813832391 11.2953711045426 50.8047359365898 0.222329097795932 0.824256729712429 NBPF8 other 1 1 1 2.80981133844422 0.222329097795932 0.000234080411000759 113.524012963551 29.8998630823904 3.79680711750187 0.000182926309666447 -155.325878266928 101.673540295696 -1.52769223748081 0.127818753347953 HIST2H4B other 1 1 1 3.79680711750187 -1.52769223748081 0.00088516384511163 5.01738990982245 2.47657841697525 2.0259362172551 0.0437473632146655 -14.3678280500192 5.7025119416747 -2.51956123844602 0.0123233840247184 POC1B-AS1 other 1 1 1 2.0259362172551 -2.51956123844602 1.52232163953411e-11 65.1871232029681 11.4054600691842 5.7154312765597 2.90984400493023e-08 -68.9323427113928 26.5067475517788 -2.60055831356672 0.00982386691393281 HMGN3-AS1 other 1.7945127486828e-07 1 0.000353080471558235 5.7154312765597 -2.60055831356672 0.291905437909482 3.01888333744941 3.19738143197338 0.944173662629359 0.345954105540077 -9.11892798115477 10.8440755848203 -0.840913354930829 0.401166211049339 LINC01235 other 1 1 1 0.944173662629359 -0.840913354930829 1.60501196828076e-22 423.096945716155 45.5196948884451 9.29481066938248 5.06406413037788e-18 -357.080523217787 131.666040993378 -2.71201686117186 0.0071152221682186 URGCP-MRPS24 other 2.41329599550694e-18 1 7.65433293306617e-14 9.29481066938248 -2.71201686117186 1.01755455410536e-09 882.926197933736 154.989560964792 5.69668171480468 3.16786357450365e-08 -131.506331494149 299.431733278952 -0.439186354946679 0.66087520072424 TAF15 other 1.09834838570132e-05 1 0.000383754993415372 5.69668171480468 -0.439186354946679 0.000127369349263361 6.05040899312507 1.53071486891748 3.95266885818122 9.93804833446387e-05 -0.563813255428412 4.7027930614304 -0.119889020857091 0.904662593408602 YTHDF3-AS1 other 0.931374666276233 1 0.932884597156123 3.95266885818122 -0.119889020857091 5.44853605981704e-11 438.352367633207 64.4586292167817 6.80052264467149 6.72480904366553e-11 -64.28194343499 160.639829368967 -0.400161925516887 0.689354846400388 HSPE1-MOB4 other 6.27289956566736e-07 1 9.03747087378211e-07 6.80052264467149 -0.400161925516887 0.823082887610035 3.12352710474894 5.75395414350009 0.542848800468354 0.587678445299043 5.84708025033332 11.1163387499834 0.525989750927844 0.599323910684936 GAS2L2 other 1 1 1 0.542848800468354 0.525989750927844 1.1840901816555e-11 993.683305877293 152.312263937961 6.52398749901082 3.32841983767928e-10 -184.773284455695 289.822524236953 -0.637539421555199 0.524309830365986 RPS10-NUDT3 other 1.40054186686212e-07 1 4.37321082472681e-06 6.52398749901082 -0.637539421555199 0.054481470598116 24.5897889791193 10.7756037342071 2.28198712440206 0.0232771787574404 5.85372365926881 31.4488541138839 0.186134720141823 0.852480451753914 LINC00221 other 1 1 1 2.28198712440206 0.186134720141823 0.000155976089345611 118.118401226117 30.2244552606187 3.90804069775976 0.000119172170328789 -157.151169432031 102.580028116571 -1.53198602415517 0.126760692371293 HIST2H4A other 1 1 1 3.90804069775976 -1.53198602415517 8.07929438244032e-05 83.1285039382025 22.6027403454451 3.67780643708339 0.000283475414574938 -19.5287158676229 43.6673133103988 -0.447215878128513 0.655075110921835 RASL10B other 0.605381528076253 1 1 3.67780643708339 -0.447215878128513 4.43976450155686e-16 97.5889049037504 11.0426377175538 8.83746324020208 1.28517625958278e-16 -54.17976728118 52.728892864532 -1.02751573829505 0.30509730623046 GPR75-ASB3 other 6.031420075365e-12 1 1.91722594404559e-12 8.83746324020208 -1.02751573829505 6.65401009855809e-11 17.7478588942109 2.49374792716429 7.11694181311758 1.03333140544918e-11 -2.69614960807672 20.9420229502215 -0.128743513197621 0.897658257678894 LPP-AS2 other 7.62815717698699e-07 1 1.42114068191426e-07 7.11694181311758 -0.128743513197621 0.00067207395230737 20.5163044090733 6.14071641456557 3.34102782541941 0.000952940277976163 -11.2153147792534 17.0876135505543 -0.656341785005407 0.512165280201837 CTAGE15 other 1 1 1 3.34102782541941 -0.656341785005407 8.81103652439707e-15 52.5615682422281 8.6013238461688 6.11086958034257 3.42017879490792e-09 -24.85143880735 13.9285976205584 -1.78420250798757 0.0755053832210146 TMEM56-RWDD3 other 1.15706531638382e-10 1 4.33165644375088e-05 6.11086958034257 -1.78420250798757 2.65000947116556e-05 9.81303012241534 2.17990807528042 4.50157978388744 1.0011611144492e-05 -5.00985511897665 9.99140576988272 -0.501416440725283 0.616483644837169 TMCC1-AS1 other 0.208820746327846 1 0.10280072947302 4.50157978388744 -0.501416440725283 0.934033785809446 8.19311005667 37.5687324439769 0.218083217710038 0.82752961824994 28.8748837715677 78.5178240639982 0.367749413789567 0.713349275767996 UGT2A2 other 1 1 1 0.218083217710038 0.367749413789567 0.0027552361377544 1949.20294205649 685.019564129994 2.84547047139021 0.0047783378639659 -3829.02672768566 2597.78803907612 -1.47395656230961 0.141671308036691 SRXN1 other 1 1 1 2.84547047139021 -1.47395656230961 0.000826839878952589 17.5497626649886 5.17151114428893 3.39354633014169 0.000793832643502028 -6.24798262465778 14.5127391151429 -0.430517118449302 0.667164247375522 CTAGE6 other 1 1 1 3.39354633014169 -0.430517118449302 0.607681679026048 26.3741087899486 26.4982860270317 0.9953137634277 0.32053466118173 9.99449070150074 89.8352296501463 0.111253577693553 0.911503474997973 NBPF10 other 1 1 1 0.9953137634277 0.111253577693553 0.147079233927304 -109.169229086981 59.7048053526931 -1.82848312530437 0.0685721384971846 -171.834379970553 115.346564249578 -1.4897225685782 0.137455810142096 MMP28 other 1 1 1 -1.82848312530437 -1.4897225685782 0.87287310319717 -85.1264414507769 176.218812243691 -0.483072382380245 0.629434369435699 -134.916070466322 339.258865883569 -0.397678834759248 0.691180007752091 CCL5 other 1 1 1 -0.483072382380245 -0.397678834759248 0.00480416161410352 2.02577526244292 0.622149785095965 3.25608930674219 0.00128777518461069 -0.983266708963731 2.09780802959 -0.468711481267379 0.639689276425539 PPIAL4E other 1 1 1 3.25608930674219 -0.468711481267379 0.45197584659058 29.3814939921224 31.8479733211007 0.922554590707844 0.357118315155066 -90.5303098668793 107.971888984599 -0.83846185074888 0.402562822838551 LIX1L other 1 1 1 0.922554590707844 -0.83846185074888 0.716916290153574 -1.03562881185827 6.4954714108178 -0.159438591344347 0.873441662912032 -11.7090300831211 14.351967199017 -0.815848442290411 0.415300689099433 MILR1 other 1 1 1 -0.159438591344347 -0.815848442290411 5.61540128712618e-07 29.5305969877101 5.87169498142219 5.02931386612277 8.98611966767283e-07 -11.1679369826046 13.5803090405246 -0.822362506573206 0.411596261606016 ATP2B1-AS1 other 0.00510552285025512 1 0.00999705813028602 5.02931386612277 -0.822362506573206 6.30440421484479e-21 186.44335436471 27.7062750658818 6.72928258747785 1.0058197642246e-10 -162.158290441715 49.0797766580102 -3.30397368292118 0.00108107729462466 MROH7-TTC4 other 9.32358339333396e-17 1 1.34407695093333e-06 6.72928258747785 -3.30397368292118 2.79744336486398e-09 5.37680903068112 3.5979919811638 1.4943916103287 0.136245391251761 -23.363648935486 5.63660005202601 -4.14498966040498 4.5575550313516e-05 BMS1P4 other 2.94850530656663e-05 0.688920018539108 1 1.4943916103287 -4.14498966040498 0.533336293073542 2.8265102588707 4.69449811366709 0.602089976485854 0.547619516729159 -14.7570106278602 18.5770196901071 -0.794369111624443 0.427678229257703 LINC01215 other 1 1 1 0.602089976485854 -0.794369111624443 8.69302719295645e-09 24.8032360052074 5.50885627262099 4.50242932067033 1.00023307388758e-05 -13.8762630959023 8.71283383592777 -1.59262340556558 0.112414708223577 SNORD58B other 8.89035891023656e-05 1 0.102733939018993 4.50242932067033 -1.59262340556558 0.460002211509557 1.73594007079823 2.11922629859537 0.819138603531306 0.413478275145034 -6.61873410779278 7.18466020861617 -0.921231333926592 0.357807261752444 ANKRD34A other 1 1 1 0.819138603531306 -0.921231333926592 8.26846152353082e-11 215.511800127358 32.7038138955907 6.58980633926657 2.26172833383223e-10 -30.9882905477395 64.7666816697246 -0.478460371117409 0.63270551820921 GTF2H5 other 9.44258305987219e-07 1 2.98819547465915e-06 6.58980633926657 -0.478460371117409 0.000701670320041108 17.0393472838554 5.30098196364503 3.21437563845981 0.00146611748254383 -5.19393830116163 9.68985270023591 -0.536018292727523 0.592387207064981 FGF14-AS2 other 1 1 1 3.21437563845981 -0.536018292727523 0.0278549981206002 18.1671270281144 6.75293962535225 2.69025462035976 0.00762482669492103 5.47300443484038 22.765306631358 0.24040987118977 0.810211137329456 NBPF25P other 1 1 1 2.69025462035976 0.24040987118977 0.0791483290403629 46.7979457156454 20.7526751016712 2.25503196510202 0.0249384986139606 20.5663114760923 37.5564992355327 0.547609918249095 0.584415539881051 CASC15 other 1 1 1 2.25503196510202 0.547609918249095 0.0529953876459884 97.1620375587813 48.9734222721024 1.98397483882047 0.0483224802692849 -221.601688403496 166.532576054949 -1.33068072117239 0.18447351527542 HIST2H2AA4 other 1 1 1 1.98397483882047 -1.33068072117239 1.6281456577356e-12 461.743745815326 79.3263448400147 5.82081207380184 1.6451495892561e-08 -353.60204516404 150.943600374744 -2.34261038087181 0.019870515128946 NUDT3 other 1.99154776854218e-08 1 0.00020215598152779 5.82081207380184 -2.34261038087181 8.59671966948682e-20 517.247214546096 56.183437665028 9.20640024966045 9.83326249043903e-18 -452.067497648165 224.780274571315 -2.01115288479079 0.0453067971976028 KMT2B other 1.25322979341779e-15 1 1.48157765943445e-13 9.20640024966045 -2.01115288479079 5.15631746638563e-17 613.900508012859 72.4355546446599 8.47512676646725 1.54497331308672e-15 -235.94443762731 230.589222581832 -1.02322404744471 0.307117815318614 POM121C other 7.16418748779619e-13 1 2.27497320352019e-11 8.47512676646725 -1.02322404744471 9.25695087544207e-05 2826.64616867702 1055.59785882913 2.67776800136023 0.00787430911420428 -3956.47832187504 1798.68119889847 -2.19965512748898 0.0286950342394726 CD24 other 0.689087423167908 1 1 2.67776800136023 -2.19965512748898 0.00139643615947158 8.32662203808351 30.0231604088879 0.277339957708734 0.781731304701157 -138.856052411373 49.09671019648 -2.82821500372805 0.00503156604912053 FAM47E-STBD1 other 1 1 1 0.277339957708734 -2.82821500372805 4.9020869961146e-05 8.82859657075814 2.30631153856783 3.82801560982541 0.000160235386523729 -1.41216412006785 3.83269728509571 -0.368451775609663 0.712821946783167 LINC01023 other 0.375702333398161 1 1 3.82801560982541 -0.368451775609663 0.25887955726474 -6.87785564120532 10.1482385150661 -0.677738863842672 0.498513367957886 -39.9932515767345 24.3720302127745 -1.64094871160024 0.101963850766314 MUSTN1 other 1 1 1 -0.677738863842672 -1.64094871160024 9.39543507302971e-09 22.6076895864154 20.8941186474785 1.08201211871378 0.280216138423858 -140.242950408439 32.7326438946984 -4.28449809491721 2.55264528190692e-05 ZSWIM8-AS1 other 9.59179966605603e-05 0.388665770623148 1 1.08201211871378 -4.28449809491721 0.000692587900248544 45.2466497700747 20.0834291576471 2.25293446726185 0.0250908575738399 -31.3021134904617 31.5259685465762 -0.992899344050801 0.321675109622279 ZNF595 other 1 1 1 2.25293446726185 -0.992899344050801 0.0222409855520159 285.96665712891 148.539746612636 1.92518611112659 0.0552487153564774 -62.2564806644057 224.787875604863 -0.276956577381608 0.782023802608606 AFAP1-AS1 other 1 1 1 1.92518611112659 -0.276956577381608 0.207810600203177 446.406158357772 253.449447737856 1.76132227685693 0.084688298181891 463.7034457478 574.935608205753 0.806531095186321 0.423999132203889 DOC2B other 1 1 1 1.76132227685693 0.806531095186321 0.180447962196028 33.9260526707337 20.7578589977496 1.63437147705897 0.103333446599864 55.7427982773731 36.213043523552 1.53930166739836 0.124888908667409 PCDHB16 other 1 1 1 1.63437147705897 1.53930166739836 0.000279893598882741 20.9046117091996 6.41002574774416 3.26123677686575 0.00125747517998152 -10.5513877507393 12.0459631859945 -0.875927278526563 0.381878083318106 GAS6-AS2 other 1 1 1 3.26123677686575 -0.875927278526563 7.94143643973188e-07 400.771060715328 80.0221741278644 5.00825008921841 9.89294361846607e-07 -331.898787579062 352.835789509005 -0.940660776053703 0.347713358763874 STAG3L5P-PVRIG2P-PILRB other 0.00712743920465937 1 0.01097721023905 5.00825008921841 -0.940660776053703 3.35010412033908e-05 4.55757317006702 2.00249313163639 2.27594946422746 0.0236324601387276 -5.57486873898591 3.02037010706022 -1.84575682495151 0.0660222155521548 JMJD1C-AS1 other 0.261140616180432 1 1 2.27594946422746 -1.84575682495151 5.85307419723173e-06 138.458724597056 32.7983692219172 4.22151246789832 3.31142566179586e-05 -94.4116608269111 78.7686300848731 -1.1985946781756 0.231728825325336 DCP1A other 0.0488439041758988 1 0.325181999988353 4.22151246789832 -1.1985946781756 9.42466031969274e-05 7.74019902393263 1.9320329320034 4.00624590591555 7.96825193132427e-05 -6.72095613559422 7.44290043375954 -0.903002289955308 0.367323667049597 TBC1D8-AS1 other 0.700911987975549 1 0.755469965608854 4.00624590591555 -0.903002289955308 2.3860778775505e-08 21.5427182598463 3.6593712568924 5.88699990996289 1.15098017079605e-08 -4.39168338685194 10.2715758267806 -0.427556926114658 0.669310783409417 RBAK-RBAKDN other 0.000237581774267703 1 0.000142548894153091 5.88699990996289 -0.427556926114658 0.00136470844445482 6.20017634812196 1.69000843616726 3.66872508765886 0.00029588297299258 8.06209984945774 12.2247702013817 0.659488867001077 0.51016785429949 LINC02012 other 1 1 1 3.66872508765886 0.659488867001077 6.98200809294269e-11 247.86937623634 40.2238635096691 6.16224685072226 2.59730852738886e-09 -149.080100767024 92.9489295439813 -1.60389260530949 0.109906808460514 ARL2-SNX15 other 7.99858847127515e-07 1 3.30325698513316e-05 6.16224685072226 -1.60389260530949 0.093401822215 3.13644417991665 2.70099373963877 1.16121860405945 0.246622100319105 -14.4999484170847 10.0630461080062 -1.44091046204673 0.150817817905917 DGCR9 other 1 1 1 1.16121860405945 -1.44091046204673 1.41593875053165e-07 86.6160160400314 15.5360989388855 5.57514575446214 5.97477774824529e-08 -33.5580564062346 60.7015080502158 -0.552837276768699 0.580830562512239 LINC02035 other 0.00134301790487927 1 0.000714762662022584 5.57514575446214 -0.552837276768699 4.01349388207504e-08 40.8518601129332 9.91394689418308 4.12064544514584 5.12921675201021e-05 -44.9171254827844 22.6801198795589 -1.98046243676459 0.0487391039027275 FAM95C other 0.000394044829342128 1 0.494866832233945 4.12064544514584 -1.98046243676459 0.00728960586577458 13.6195716502183 5.13079575846049 2.65447550270543 0.0084111641237285 -27.7577056574802 21.9357764720311 -1.26540793725138 0.206808036760752 C2orf15 other 1 1 1 2.65447550270543 -1.26540793725138 7.12569252052854e-05 69.1731839485874 16.6953554065148 4.14325914389308 4.59483040521978e-05 22.8001937647719 23.8609695509781 0.955543475132477 0.34016404947473 ZBTB8B other 0.536778417571415 1 0.445260559608303 4.14325914389308 0.955543475132477 0.00195587524419393 69.0196527702825 24.5817586234752 2.80775894953138 0.00535540510016866 -263.325273959332 159.200374863517 -1.65404933364687 0.099288220699179 C1QTNF3-AMACR other 1 1 1 2.80775894953138 -1.65404933364687 0.0219888420284835 8.26714480078288 3.01281175862702 2.743996460154 0.00647185479105874 0.955134910483264 8.45673266200212 0.112943727637848 0.910158175124041 RBAKDN other 1 1 1 2.743996460154 0.112943727637848 3.24080228010453e-07 56.1456331107552 14.2369449043071 3.94365739898096 0.000102694824549513 -63.6202350378422 35.9516807926409 -1.769603913786 0.0779388198079936 PAXIP1-AS1 other 0.00300325147297287 1 0.962147811204387 3.94365739898096 -1.769603913786 0.0050252532863364 13.5566718459554 4.13048952997083 3.2820981018323 0.0011655492431236 9.7130183920765 7.2966530243143 1.33116078833819 0.184254869958172 HIST1H4K other 1 1 1 3.2820981018323 1.33116078833819 4.66815871659815e-12 100.76409859051 20.5257714379099 4.90915037689665 1.60398838049505e-06 -104.772188768356 39.2787738324314 -2.66739968043119 0.00811654642176327 CWC25 other 5.59852274881616e-08 1 0.0175380089523329 4.90915037689665 -2.66739968043119 0.00218350175372541 4.86209898035319 11.412265139038 0.426041536988252 0.670547468445472 -47.097847412197 18.0611215620273 -2.60769228812557 0.00982082419313498 SMIM11B other 1 1 1 0.426041536988252 -2.60769228812557 3.76559025811169e-08 171.788694778408 31.5444424997496 5.44592584826224 1.16920968721009e-07 21.5212911187112 60.0440657204001 0.358424947752986 0.720308550908236 EPOP other 0.000370232834177541 1 0.00137744593250221 5.44592584826224 0.358424947752986 6.01213576775923e-21 221.139960019467 30.475645970364 7.25628458325428 4.26316448657725e-12 -197.506877268346 58.3829151243367 -3.38295675794401 0.000823767981862461 ZNHIT3 essential 8.89375244124623e-17 1 5.92025652250982e-08 7.25628458325428 -3.38295675794401 0.556647265551993 -9.8368129448888 18.3923503862417 -0.534831750065353 0.593209656272384 -38.1464922580171 35.2244421817801 -1.08295518382257 0.279801692009885 LHX1 other 1 1 1 -0.534831750065353 -1.08295518382257 2.40291936466438e-16 698.958636094761 125.139486767564 5.58543633308181 5.82887644011706e-08 -950.843213057556 261.27805244321 -3.63920047691042 0.000329392587215445 CYFIP1 other 3.28647281505147e-12 1 0.000697891376175216 5.58543633308181 -3.63920047691042 0.129647665755905 34.7107935702012 18.4360787890317 1.88276444071458 0.0608073864091631 -0.464156794365179 32.3234433927565 -0.0143597570569846 0.988553570182114 HIST1H2BG other 1 1 1 1.88276444071458 -0.0143597570569846 7.57001300995524e-14 373.594732256352 55.5655630671917 6.72349404260673 1.04685069289065e-10 -67.3132607653461 85.8602616311816 -0.783986206034342 0.433732895719408 TAF9 other 9.68810265014072e-10 1 1.39796441528617e-06 6.72349404260673 -0.783986206034342 5.5757280881939e-10 11.6359076984964 2.01254660006476 5.78168361324999 2.03886587181968e-08 -2.00903769880029 3.84647944912897 -0.522305584982452 0.601885842620202 FRMD6-AS1 other 6.10876769342523e-06 1 0.000249251352829956 5.78168361324999 -0.522305584982452 0.328760430150903 11.7920133179679 8.09819372222596 1.45612882606204 0.146514548250997 3.50904202305237 14.1076109316295 0.248733966371659 0.80375496888101 HIST1H3G other 1 1 1 1.45612882606204 0.248733966371659 0.512859323144324 -42.8885241089815 234.213654025335 -0.183117095745162 0.854845115296776 -469.942077730958 434.231434266397 -1.08223873410936 0.280122893380439 RN7SL2 other 1 1 1 -0.183117095745162 -1.08223873410936 0.00208811462320482 22.6019282544747 6.50608865300986 3.47396561281386 0.000603143912209279 18.6914655731166 22.0571235313526 0.847411746438654 0.397566581476886 LINC01138 other 1 1 1 3.47396561281386 0.847411746438654 0.00497035763229694 4.40393139573639 1.99163803900072 2.21121072679754 0.027992930427784 -4.14803198514276 3.9692325835688 -1.04504634027094 0.297084521349797 FAM27E3 other 1 1 1 2.21121072679754 -1.04504634027094 2.20948033803295e-13 427.823508877712 53.3467941461828 8.01966670584505 3.27462344700061e-14 -108.537070366601 229.08380693409 -0.473787614319804 0.636035669518372 INO80B-WBP1 other 2.78637565429335e-09 1 4.73346819263939e-10 8.01966670584505 -0.473787614319804 0.00271122224106145 9.34795738633521 3.3144974178352 2.82032423257721 0.00515598649692882 -12.4826462905695 11.2610813003384 -1.10847670464775 0.268649762814833 CASTOR2 other 1 1 1 2.82032423257721 -1.10847670464775 0.000149846021982602 13.7740502358577 21.6270680819025 0.636889391742552 0.524730582021621 -167.666961237317 52.9325608216964 -3.16755808966251 0.00171178679155878 NATD1 other 1 1 1 0.636889391742552 -3.16755808966251 3.10951751559919e-09 234.462972784659 51.2243630298272 4.57717693137804 7.22881920981052e-06 -175.447129233873 98.0559537343956 -1.78925524205401 0.0747070976718754 SOCS7 other 3.26530434313071e-05 1 0.0751580333244 4.57717693137804 -1.78925524205401 0.0186309915178848 3.84727657760204 2.59252010014451 1.48399103150159 0.138982060130642 -7.21176375554224 4.96655201704543 -1.45206649015074 0.147648455352492 TBC1D3H other 1 1 1 1.48399103150159 -1.45206649015074 1.7712822236513e-05 4.65129151291512 2.07428637335496 2.24235745491211 0.0257441590730473 -6.8317343173432 3.01082350989567 -2.26905838050265 0.0240482252611465 SNORA73A other 0.142074547159071 1 1 2.24235745491211 -2.26905838050265 0.00271122005049677 175.551852772942 57.9128201286523 3.03131245176728 0.00276556770177714 34.694651061724 91.6531881795711 0.37854276267781 0.70543923468477 CBSL other 1 1 1 3.03131245176728 0.37854276267781 0.0704946961871302 85.5845904706964 38.126818830864 2.24473462762162 0.0256198862199871 -35.9554546559349 171.018629345121 -0.21024291209454 0.83364149620617 ADRA2B other 1 1 1 2.24473462762162 -0.21024291209454 0.00861297154051721 16.6327665673115 5.69119656722558 2.92254297858839 0.00376580635624682 0.778142001337061 9.97821023563916 0.0779841257060081 0.937898441057029 HIST1H2BE other 1 1 1 2.92254297858839 0.0779841257060081 8.05077704324787e-07 10.4947002318648 6.03359099322651 1.7393787950901 0.0833002091985557 -44.1016292419075 12.0811995213391 -3.65043464136244 0.000323771893626181 ZNF658 other 0.00721913177468036 1 1 1.7393787950901 -3.65043464136244 9.81686184750836e-27 25.0499762932032 2.41903901678482 10.3553419847264 2.22254005312425e-21 -5.0043500145928 4.5339378559357 -1.1037535523433 0.270682787239322 TMEM269 other 1.51709782991394e-22 1 3.42382295183791e-17 10.3553419847264 -1.1037535523433 0.0151209704877657 -2.3313160819424 3.17667684695089 -0.733885187024955 0.463665075888453 -17.1853576329945 6.06627756792999 -2.83293295444421 0.00496536611036036 TBC1D3D other 1 1 1 -0.733885187024955 -2.83293295444421 2.81804684299722e-19 334.034652375376 36.8134644445054 9.07370869370141 2.55018364349377e-17 -175.553832527697 125.07459315731 -1.4035930727106 0.16159768607712 RCC1L other 4.07658656307978e-15 1 3.82986579579895e-13 9.07370869370141 -1.4035930727106 0.000326600206401897 129.467161652837 34.1691515621597 3.78900721070914 0.000188140672513701 3.2135437843439 97.2312133365399 0.0330505366956707 0.973659742870792 PI4KAP1 other 1 1 1 3.78900721070914 0.0330505366956707 0.0451212976842986 -1.78949503229213 2.92167796253732 -0.612488801037487 0.540737644401219 -13.537053503249 5.57932403538858 -2.42628917363216 0.0159192789021077 TBC1D3 other 1 1 1 -0.612488801037487 -2.42628917363216 0.84133830655713 -1.70718033991649 4.31446043568474 -0.39568802759123 0.69264650962615 -4.70978329249454 8.29689052624101 -0.567656434371246 0.570738245701535 CCL23 other 1 1 1 -0.39568802759123 -0.567656434371246 0.198342148063737 10.1557976474162 8.8650705438789 1.1455969354275 0.252976337050777 -13.1669498538682 15.4270630050635 -0.853496861297999 0.394140376737095 HIST1H3E other 1 1 1 1.1455969354275 -0.853496861297999 5.4669916593157e-06 126.13433021697 28.0671976078772 4.49401226225626 1.03344732264163e-05 -202.343025175941 137.687684551991 -1.46957969287032 0.142827073065222 NPHP3-ACAD11 other 0.0457641871801317 1 0.106011026356578 4.49401226225626 -1.46957969287032 0.00680905041397582 3.01613138774963 2.0851641451806 1.44647192151311 0.149196234899849 -3.76499653153866 3.3494825984768 -1.12405316965994 0.261981503820149 PANO1 other 1 1 1 1.44647192151311 -1.12405316965994 0.0372465723147656 3.69179996862693 2.6305320016173 1.40344233271336 0.161638259890475 -6.35117575211535 5.03937231491734 -1.26031087905826 0.208649405545284 TBC1D3I other 1 1 1 1.40344233271336 -1.26031087905826 3.7104462554328e-24 104.073762557667 9.17505887302192 11.3431165944539 1.08629553728013e-24 48.0357588928075 31.4615840221892 1.52680675133613 0.127966783381356 ZNF280B other 5.65360695940296e-20 1 1.69592459280174e-20 11.3431165944539 1.52680675133613 1.53770381057911e-06 556.851787540104 168.892774214936 3.29707289212649 0.00110946021011406 -654.753988647182 321.483216409445 -2.03666616242037 0.0426700306999412 MLLT6 other 0.0134933509378317 1 1 3.29707289212649 -2.03666616242037 1.41244676823522e-16 590.35105271799 64.4402047818887 9.16122248084339 1.42634713256454e-17 135.755625189487 317.295816490927 0.427851922823475 0.669105117111792 PPP4R3B other 1.9419730616466e-12 1 2.1470803386494e-13 9.16122248084339 0.427851922823475 9.17198258829287e-07 120.308812601508 42.8992631536368 2.8044493951013 0.00541332865269245 -219.41509036569 80.1996710657216 -2.7358602279788 0.0066420842854897 SYNRG other 0.00818691165831021 1 1 2.8044493951013 -2.7358602279788 1.02772945182856e-09 29.5551468892427 14.8292502996868 1.99303041569586 0.0472570738783104 -96.3095403876782 24.6485616466494 -3.90730874151312 0.000117846891260133 NUDT18 other 1.10871453263265e-05 1 1 1.99303041569586 -3.90730874151312 0.00561373960564375 18.3631082610336 6.20530985885814 2.95925726171756 0.003369305356554 -24.2032093549604 27.5842135155658 -0.877429742243784 0.381066429042665 ZNF2 other 1 1 1 2.95925726171756 -0.877429742243784 7.41589944968788e-06 21.3886794137341 8.5953502478803 2.48840114677221 0.0134284059153344 -64.0987327331794 21.0866883198918 -3.03977237965399 0.00259737763588762 LENG9 other 0.0613888156445163 1 1 2.48840114677221 -3.03977237965399 0.673306948737904 -18.0968016857787 26.6770042413208 -0.678367088076105 0.498122110973789 -42.1532956677992 51.1508814905415 -0.824097150223969 0.410614440300651 CCL4 other 1 1 1 -0.678367088076105 -0.824097150223969 1.43656777955964e-07 118.989108168656 55.2693815261159 2.15289378826198 0.032216255925732 -273.69396525423 93.1583942419186 -2.93794206610611 0.00359036602183986 PRAG1 other 0.00136157894146662 1 1 2.15289378826198 -2.93794206610611 0.391138969851847 -327.748448906421 260.755788468925 -1.25691725131341 0.209869845768248 -46.5046784512727 502.634849126453 -0.0925217949612822 0.926352087627998 CCL18 other 1 1 1 -1.25691725131341 -0.0925217949612822 0.0465126371991191 -42.2777768972912 44.554329135902 -0.948903904900762 0.343508719946454 -787.66864957469 322.517934987268 -2.44224759037287 0.0152308000698124 FCGBP other 1 1 1 -0.948903904900762 -2.44224759037287 0.623697865536182 -3.14099656074977 17.643914029055 -0.178021529439406 0.858841564673574 -31.1796875082666 33.6933484397938 -0.925395929822208 0.355598770321806 HNF1B other 1 1 1 -0.178021529439406 -0.925395929822208 0.689415428217029 -32.7151552889829 58.813185718176 -0.556255453424153 0.578495234519298 -95.1273689658027 113.10025220471 -0.841088919886962 0.401039649731858 CCL15 other 1 1 1 -0.556255453424153 -0.841088919886962 7.18639189932779e-14 389.338570556032 61.7900343650797 6.30099294419658 1.21468086418109e-09 -212.647798846429 117.691790924188 -1.80681929620229 0.0719161632246555 AATF essential 9.20217482708923e-10 1 1.56560216584301e-05 6.30099294419658 -1.80681929620229 0.129683521265008 36.1191352201367 17.8521613980661 2.02323597769228 0.0440304005448174 28.5313572700627 31.0996940714508 0.917416010733501 0.359740414217903 HIST1H2BH other 1 1 1 2.02323597769228 0.917416010733501 0.0140817999313268 5.35207112266883 1.98093238787652 2.70179394078465 0.00732843928322996 8.40320960305852 3.53974269762639 2.37396057309289 0.0182904203705889 HNRNPCL2 other 1 1 1 2.70179394078465 2.37396057309289 0.0296388566278404 1.89986819515663 2.08686788512516 0.910392176092489 0.363462192755057 -11.8249644497201 5.93835922951297 -1.9912847964723 0.0475000150457338 RIMBP3 other 1 1 1 0.910392176092489 -1.9912847964723 0.305784777789488 -34.4466872575632 192.474717089106 -0.1789673354429 0.85809907845466 -524.975155731652 368.443663085485 -1.42484512105681 0.155369801326365 ARHGAP23 other 1 1 1 -0.1789673354429 -1.42484512105681 1.61035219329758e-15 132.080359323461 18.4981271299191 7.14020172938656 9.17676641418e-12 -43.9074040283529 38.6221388244093 -1.13684548201674 0.25664157729431 TUBGCP5 essential 2.15819400945741e-11 1 1.26409957355329e-07 7.14020172938656 -1.13684548201674 1.34206460635113e-05 170.730042278041 50.7057379508514 3.36707538786887 0.000915167568196197 -70.4629910143463 80.2472152430052 -0.878073971800389 0.380984186408025 U2AF1L5 other 0.108707233114441 1 1 3.36707538786887 -0.878073971800389 0.167773749246287 -50.4638549940563 30.0316392855864 -1.68035632401447 0.0940318299696466 -118.459284501112 82.0790882989473 -1.44323343443657 0.150101177310165 PRSS2 other 1 1 1 -1.68035632401447 -1.44323343443657 0.00930128237699232 4.11219285579256 2.19444912803656 1.87390666899253 0.0620272608474552 -5.43483387699887 4.20395804936906 -1.29278975031983 0.197193047300691 TBC1D3F other 1 1 1 1.87390666899253 -1.29278975031983 2.10944467557789e-09 200.533886577524 51.6455539940254 3.88288770415209 0.000130398323959951 -270.944872850246 96.5507595665233 -2.80624278945797 0.00538416817553652 DUSP14 other 2.24001930099616e-05 1 1 3.88288770415209 -2.80624278945797 4.47429964199686e-07 131.91735243457 55.4766759768147 2.37788854706619 0.0181007632039549 -283.972898724359 101.8481885607 -2.78819783382908 0.0056727562479174 UHRF1 other 0.00410159048181852 1 1 2.37788854706619 -2.78819783382908 0.370800213646622 193.280155272354 200.556109560912 0.963721103762494 0.336064360968153 -133.051717585834 365.989339372766 -0.363539871991513 0.716491479799092 RN7SL1 other 1 1 1 0.963721103762494 -0.363539871991513 0.0007744936052498 89.2961522835171 25.7021721793923 3.47426480766921 0.000596221711215792 -6.50357919980778 44.7439278107947 -0.145351101658061 0.884541717843973 HIST1H4I other 1 1 1 3.47426480766921 -0.145351101658061 0.00119638408653798 -11.9370945052176 3.57280343368016 -3.341100266723 0.000950900856174723 -28.9095663524193 11.0796650486412 -2.60924551649372 0.00957460716171538 PIK3R6 other 1 1 1 -3.341100266723 -2.60924551649372 4.14314154795747e-13 97.4417625203014 19.0980377060349 5.10218714719106 6.40861763916703e-07 -105.676351406471 35.7035582764992 -2.95982687742442 0.00335668697516944 TADA2A essential 5.17561242170847e-09 1 0.00719880019407632 5.10218714719106 -2.95982687742442 0.536906024182231 5.61924894304899 5.54945040165251 1.01257755927969 0.312516740753874 8.57546366424756 8.78259461076068 0.976415745495148 0.330068228909343 KCNE1B other 1 1 1 1.01257755927969 0.976415745495148 2.69982732553393e-11 312.15369706455 68.336207255694 4.56791076941924 7.55446871267865e-06 -356.595248321171 130.810011675339 -2.72605470907084 0.00683699853498357 PIP4K2B other 3.1471887133749e-07 1 0.0783322860817649 4.56791076941924 -2.72605470907084 0.702176343854039 -32.4758959152435 60.1733259376221 -0.539705848217683 0.589843085886923 -94.9826309508315 115.715859571913 -0.820826387171271 0.412466614221628 CCL14 other 1 1 1 -0.539705848217683 -0.820826387171271 0.00224144844862318 220.89312018804 190.228231481253 1.16120051407726 0.246578396787284 -790.440984765688 321.864673139257 -2.45581777290513 0.0146821393497296 PCDHGB5 other 1 1 1 1.16120051407726 -2.45581777290513 0.000347897890256248 159.935694806908 65.3854665511617 2.44604349013499 0.0151041327766484 -228.333737338195 137.192489972377 -1.6643311699071 0.0972463048758065 HERC2P2 other 1 1 1 2.44604349013499 -1.6643311699071 0.304772641617583 32.7248985936897 48.914388852765 0.669023969453927 0.50404554075787 -182.355015732694 138.307753142323 -1.31847283749194 0.188450468312911 RAB7B other 1 1 1 0.669023969453927 -1.31847283749194 0.622361466600456 -16.177229607613 32.6009849923426 -0.496219044038478 0.620174128910229 -53.7445449615251 55.2029921167867 -0.97358028796381 0.331202292507397 DACH1 other 1 1 1 -0.496219044038478 -0.97358028796381 0.320577073311548 4.39588291398181 4.79757045237058 0.916272717122833 0.360341526894658 -6.58740438288713 8.41144143038816 -0.783148101000703 0.434226530860891 HIST1H4E other 1 1 1 0.916272717122833 -0.783148101000703 8.80318342700216e-10 508.545858728395 90.5899357442995 5.61371254488826 4.94187516165702e-08 -574.166596611324 307.781392714215 -1.86550132725033 0.0632037353631069 GTF2IP1 other 9.54000987984224e-06 1 0.000594112231934407 5.61371254488826 -1.86550132725033 0.0134482592215442 24.5616698588014 9.08420760719667 2.70377680925557 0.00729085589396168 -1.33234538238587 15.808406984879 -0.0842808123336074 0.932895623569961 HIST1H2AE other 1 1 1 2.70377680925557 -0.0842808123336074 0.051026599229322 46.8191031492944 19.1132348217502 2.44956458631565 0.0149762225199122 -2.89562910625247 64.7431203839997 -0.0447248926075562 0.964361595370321 LINC00869 other 1 1 1 2.44956458631565 -0.0447248926075562 7.34411234259611e-05 37.4191483605258 8.61252750630805 4.34473484504044 1.98318036059821e-05 12.4193811717232 28.4245346085585 0.436924697018039 0.662519109827614 TYW1B other 0.552571012656931 1 0.198631350481081 4.34473484504044 0.436924697018039 7.82207473338298e-11 82.6124157106398 15.439873123063 5.3505890270069 1.88238906934683e-07 -50.2323247148225 29.5699520015771 -1.69876247050193 0.0905244585174115 PIGW other 8.9437602501501e-07 1 0.0021894067265573 5.3505890270069 -1.69876247050193 0.0110216578605227 5.92642549026718 2.31348704860509 2.56168518161383 0.0109580314537305 -3.42052415993038 4.7270173116082 -0.723611515348285 0.469928403636347 SNORD22 other 1 1 1 2.56168518161383 -0.723611515348285 0.6938971182509 1.35886703284712 8.32087380363373 0.163308213165509 0.870397037818307 -11.6123746516034 17.7431381019975 -0.654471299544025 0.513361219174045 RPPH1 other 1 1 1 0.163308213165509 -0.654471299544025 0.513631488657978 2.38590626766826 3.89493763823798 0.612565973905455 0.540678931038464 -4.6959772794624 6.82888143995149 -0.687664198120235 0.492254572221573 HIST1H2BF other 1 1 1 0.612565973905455 -0.687664198120235 3.81898241064686e-06 6.46484894847052 1.90416661288217 3.39510676467815 0.000789508306551626 -9.05457686015065 4.16961985401089 -2.171559321275 0.0307629157133831 GTSE1-AS1 other 0.0323964277895173 1 1 3.39510676467815 -2.171559321275 1.9912837084849e-10 323.247458727415 58.5249090038336 5.52324581497839 7.94060211976393e-08 -112.457316039397 111.651057783845 -1.00722123257545 0.314747266303833 PCGF2 other 2.23322467906582e-06 1 0.000943740561933943 5.52324581497839 -1.00722123257545 0.000399157729759696 52.0522987967846 17.9611328934928 2.89805209423304 0.00406648315911874 -34.7568142347571 34.3819993426983 -1.01090148622024 0.312978800557007 SRCIN1 other 1 1 1 2.89805209423304 -1.01090148622024 0.0349663057789575 -2.63945494052818 2.0315095901613 -1.29925792785384 0.194951590193923 6.13795709186591 3.90464557301019 1.57196267294857 0.117117426886017 MIR6891 other 1 1 1 -1.29925792785384 1.57196267294857 6.5103584865795e-05 507.747390670975 284.55813547223 1.78433623002329 0.0754795266450071 -1630.51304937311 518.706294268182 -3.14342252521443 0.00185396916209835 MARCKS other 0.493159655358397 1 1 1.78433623002329 -3.14342252521443 7.6396052041894e-07 13.6519791247076 2.62488257367119 5.20098661237016 3.92243841285841e-07 -1.99430428950299 8.73637473051809 -0.228275955532956 0.819604503281126 CEBPB-AS1 other 0.00686647715752543 1 0.00447040305913473 5.20098661237016 -0.228275955532956 5.94258181423518e-07 21.25984439326 4.65724353009091 4.56489858344277 7.59830990350926e-06 -31.1959161883271 12.6545518847125 -2.46519327373525 0.0143164555878387 ZNF670 other 0.00538932744732988 1 0.0787564821498735 4.56489858344277 -2.46519327373525 0.496217211709539 13.8798366963189 23.6408361408909 0.587112765961411 0.557618589784906 -74.5341392237692 88.1991646194581 -0.845066271833212 0.398822051725935 GPIHBP1 other 1 1 1 0.587112765961411 -0.845066271833212 0.00542273074702969 623.287765487958 209.117157872067 2.98056731370302 0.00313644852797236 274.45142714646 349.695164121625 0.784830490395358 0.433233478717684 NEFL other 1 1 1 2.98056731370302 0.784830490395358 0.989901796516711 -2.83555989084485 22.3872913965951 -0.126659355105197 0.899304287493997 -0.0320267317657292 43.1539138576728 -0.000742151265151929 0.99940839705125 CCL3 other 1 1 1 -0.126659355105197 -0.000742151265151929 0.00812473377456767 1.45310836268328 2.11949074386917 0.685593162832409 0.493698108159094 -11.8398770434539 4.94289340785838 -2.39533327274072 0.0174507043286028 PGM5P2 other 1 1 1 0.685593162832409 -2.39533327274072 1.02132504092793e-09 628.44473784782 148.135080501035 4.24237618612852 3.05984416155672e-05 -688.007452364922 283.562000117486 -2.42630342598749 0.0159211964297532 PSMB3 essential 1.10221398416942e-05 1 0.301670035887877 4.24237618612852 -2.42630342598749 0.521952589792575 -2.45319766622509 4.25730812544787 -0.576232115209424 0.564936552527018 -16.4994433326757 16.3129313012965 -1.01143338544951 0.312711239548508 SRD5A2 other 1 1 1 -0.576232115209424 -1.01143338544951 2.7469339054118e-16 217.941759508042 35.0597438573065 6.21629639951355 1.9592350522981e-09 -184.818319901455 66.7298979271789 -2.76964787362846 0.00600682211043418 CISD3 other 3.7514876346209e-12 1 2.50488201436312e-05 6.21629639951355 -2.76964787362846 5.3964823012099e-05 13.0248817650211 2.8874892802195 4.51079830988359 9.60188899308267e-06 12.3422621127757 8.40554081254179 1.46834836544485 0.143160865223304 SNORA67 other 0.411967458874364 1 0.0987362245158691 4.51079830988359 1.46834836544485 1.4008635022174e-09 12.6621021921084 2.39267832434811 5.29202027002866 2.49952464368278e-07 -5.07480781187721 4.60641701307118 -1.10168223968367 0.271577327951064 RDM1 other 1.50172567437706e-05 1 0.00288745086838235 5.29202027002866 -1.10168223968367 1.43142139120106e-19 247.371657427202 34.1085970494776 7.25247236256498 4.46942708996031e-12 -179.162422641673 64.7842317898175 -2.76552515468484 0.00608109032630613 DDX52 essential 2.07999842355426e-15 1 6.19998925919294e-08 7.25247236256498 -2.76552515468484 3.18252298757386e-05 48.3735337330892 14.684901821117 3.29409990767031 0.00112027708806862 -63.2870545573067 35.3189655005173 -1.79187169444076 0.0742815616114853 ZNF8 other 0.248650521019146 1 1 3.29409990767031 -1.79187169444076 5.60193009322451e-09 8.46602447279351 2.83971761134471 2.98129097026114 0.00313025568888311 -15.3167274147357 4.48699345814241 -3.41358362957737 0.000738810993986619 TSC22D1-AS1 other 5.79407629542211e-05 1 1 2.98129097026114 -3.41358362957737 3.09723612606313e-06 14.1010289990647 4.43432575474115 3.17997138211777 0.00168613722833971 -22.3282676601074 10.33454972272 -2.16054576727419 0.0318158811869074 GLIDR other 0.0264596882249573 1 1 3.17997138211777 -2.16054576727419 0.0440913051697482 -639.382978821322 258.6444882232 -2.47205337029862 0.0140461648347683 -243.074262680709 881.685120296972 -0.275692826253931 0.782993337516971 MIR650 other 1 1 1 -2.47205337029862 -0.275692826253931 7.97849440958681e-09 314.678910872372 82.258621545654 3.82548242311262 0.000162307277478731 -420.444892024407 157.584785064607 -2.66805511618418 0.00809226699323437 MYO19 other 8.17950556988261e-05 1 1 3.82548242311262 -2.66805511618418 7.60283682067204e-07 7.0327657493442 2.89482421789731 2.42942756450081 0.0157704411129931 -11.4204196861246 4.20183294082175 -2.71796138660647 0.006990450362589 SNORA61 other 0.0068364708691483 1 1 2.42942756450081 -2.71796138660647 0.0257300420587851 -0.99979789863964 2.22205063075844 -0.449943797319498 0.653117420273675 -10.9331291392422 4.24329465841415 -2.57656609294445 0.0105184371552461 TBC1D3C other 1 1 1 -0.449943797319498 -2.57656609294445 2.46967341218938e-15 218.149123879879 40.8185237689 5.34436583534873 1.94175782702049e-07 -286.117972489257 78.1743333640915 -3.65999887912932 0.000303721888008999 GGNBP2 other 3.29330949515453e-11 1 0.00225651677078051 5.34436583534873 -3.65999887912932 0.0777529851266369 23.1329718464774 14.7989842203318 1.56314592285975 0.119180957754508 -44.5194803524116 42.6558995577268 -1.04368869989866 0.297556129112547 ZNF229 other 1 1 1 1.56314592285975 -1.04368869989866 6.71545250358155e-11 80.9679272359612 17.4143654353929 4.64949053333878 5.22878022988518e-06 -88.9596226445864 33.3514366315164 -2.66734004976929 0.00811080520774259 DHRS11 other 7.69792320485553e-07 1 0.0549126499742541 4.64949053333878 -2.66734004976929 1.17594329243403e-09 495.128671028773 108.429796204105 4.56635250053183 7.60667687169129e-06 -446.142408609851 208.89568845025 -2.13571860635172 0.0336191143430555 ACACA other 1.26496219967128e-05 1 0.0788355990982086 4.56635250053183 -2.13571860635172 0.00772637889357007 9.44081706185568 2.99982458158428 3.14712304173124 0.00184166375171654 9.35287524682256 8.53625479501904 1.09566495745652 0.274243200820668 TMEM191B other 1 1 1 3.14712304173124 1.09566495745652 0.0340124455467629 -1.80173997631922 4.11632163560883 -0.437706315447512 0.661954383536714 -19.469960436807 7.86065149322529 -2.47688890082294 0.013875369840244 TBC1D3E other 1 1 1 -0.437706315447512 -2.47688890082294 1.98668237898154e-05 166.134049021471 45.2232449862532 3.67364281514897 0.00028849144846331 -154.858363417569 92.3602925879586 -1.6766768389142 0.0947673706005496 C11orf98 other 0.158576987490307 1 1 3.67364281514897 -1.6766768389142 1.14548456872022e-08 49.1924508532896 10.4694002190532 4.6986885422304 4.18964063543825e-06 -29.8779649062726 20.0506610057743 -1.49012368707786 0.137367659890793 MRM1 other 0.000116255228879415 1 0.0443557254073847 4.6986885422304 -1.49012368707786 0.115030784032985 5.45493846415306 8.49972551717054 0.64177819073491 0.521561681017092 -27.1147886096835 16.5539076670947 -1.63796906174493 0.102592970067044 GOLGA6L10 other 1 1 1 0.64177819073491 -1.63796906174493 6.87715896099103e-05 26.9398873455206 7.17119122889914 3.75668232593711 0.000210654874860509 -28.6179996824002 21.9379149619803 -1.3044995265957 0.193166008973593 NKILA other 0.519638131092482 1 1 3.75668232593711 -1.3044995265957 0.285402987767691 -146.784825567214 248.067147800735 -0.591714085756821 0.554566276193132 -607.731211478182 390.770124190491 -1.5552141114604 0.121135290744741 MIR6723 other 1 1 1 -0.591714085756821 -1.5552141114604 0.000409762312659556 7.75136486014856 1.98807155706463 3.8989365511538 0.000123826034305521 7.00161913546392 6.74001573941919 1.03881346960583 0.299883260346377 LINC00624 other 1 1 1 3.8989365511538 1.03881346960583 0.012924436181397 49.0297442844699 17.5410455381699 2.79514377736376 0.005558417843251 2.07047462881062 30.9868653695936 0.0668178147132724 0.946776009170317 HIST1H3H other 1 1 1 2.79514377736376 0.0668178147132724 3.14318883448227e-21 298.685659404329 36.7998342751719 8.11649468774501 1.77018670211915e-14 -150.382873130043 70.2988878128044 -2.13919277827681 0.0333271180332558 MRPL45 essential 4.66794973808963e-17 1 2.57048811014722e-10 8.11649468774501 -2.13919277827681 0.00121246326651095 6.10760880227578 1.82022040099735 3.35542267240233 0.000905727442382015 -2.44427868423634 4.21577511206808 -0.579793423334975 0.562535634475007 CEP83-AS1 other 1 1 1 3.35542267240233 -0.579793423334975 0.000909261283889494 -0.958676422409097 1.54306111056995 -0.621282213544347 0.534932362483773 -9.1304393724291 2.54412597856851 -3.58883146878068 0.000393632475486632 EPB41L4A-AS2 other 1 1 1 -0.621282213544347 -3.58883146878068 1.7714206303498e-07 86.3533010962559 29.7746425325661 2.90022965017318 0.00403453595240786 -155.687907055796 48.8552466578525 -3.18671826889185 0.00160744216363854 HEIH other 0.00166920965997862 1 1 2.90022965017318 -3.18671826889185 6.80087706226954e-09 6.52677686694889 1.08874095860594 5.99479317404021 6.4299213327002e-09 -1.3183301151874 3.26163567909991 -0.404192940258492 0.686387306156737 C17orf100 other 7.00014276019404e-05 1 8.04833253214084e-05 5.99479317404021 -0.404192940258492 1.25776872504813e-05 3.2754008703702 0.762048223163743 4.298154330407 2.41277960246875e-05 -2.55323987164851 2.7011952523508 -0.945225958555374 0.345394931844841 RBM12B-AS1 other 0.102118242786657 1 0.240095698241666 4.298154330407 -0.945225958555374 0.0802842348858194 3.36881962978265 1.9829653300387 1.69887974275218 0.0904852608526458 -2.38689126866255 3.67493612084685 -0.649505512523717 0.516559781419611 MIR3911 other 1 1 1 1.69887974275218 -0.649505512523717 0.0221688512820786 1.54017118635491 0.583331687733386 2.64030091068677 0.0088109249940339 -1.58242284353069 1.96691846201093 -0.80451878107487 0.42187110113959 PPIAL4F other 1 1 1 2.64030091068677 -0.80451878107487 1.17740238398112e-07 6.66826822145042 1.53349925063833 4.34840005215177 1.9427737668018e-05 -6.63384630920457 2.80294818598924 -2.36673882962389 0.0186488658520216 GVQW2 other 0.0011225354328876 1 0.194782497859549 4.34840005215177 -2.36673882962389 0.937831233569908 0.0116688362375134 1.33941050431768 0.0087119193106953 0.993055391745665 -1.10861966691086 3.25262800396363 -0.340838136288533 0.733489523520818 GABARAPL3 other 1 1 1 0.0087119193106953 -0.340838136288533 0.198292473826113 3.69367072867446 2.54468521612598 1.45152363257633 0.148241016760044 -0.0725484137570677 4.02723459940742 -0.0180144493612919 0.985645744956438 LINC01670 other 1 1 1 1.45152363257633 -0.0180144493612919 0.468643059282053 9.95189293465155 13.2058278112552 0.753598568517578 0.451980999578308 25.5106351483955 20.6950012994984 1.23269550840829 0.219143686803691 LINC01667 other 1 1 1 0.753598568517578 1.23269550840829 1.00232527106962e-05 15.6747339709889 3.77932982169991 4.14749035159323 4.51580381116286e-05 -15.6582773339845 10.6422191535997 -1.47133573439786 0.142373549592059 UCKL1-AS1 other 0.0821205094587343 1 0.438168443797132 4.14749035159323 -1.47133573439786 9.07301906778116e-06 79.2871262942518 20.1888918618248 3.92726489581015 0.000108970400428485 -72.8334246634538 41.2784256644048 -1.76444288974566 0.0787798009303734 THRIL other 0.0746437278706356 1 1 3.92726489581015 -1.76444288974566 4.61854395532661e-08 15.9452597550964 7.54245843478116 2.11406663927596 0.0354197015415546 -48.4803806412851 13.0806357554077 -3.70627097549466 0.000254819764529027 CCDC163 other 0.000451693598830942 1 1 2.11406663927596 -3.70627097549466 0.481364258843573 21.0806651131455 20.0807076487427 1.04979692358926 0.294739917881512 2.92202845036741 30.4032698660874 0.0961090193008064 0.923504500890418 SH3PXD2A-AS1 other 1 1 1 1.04979692358926 0.0961090193008064 0.000913395893806108 4.98722864204126 1.59528550042142 3.12622953115527 0.00196182260754824 -3.01841783002691 4.16735294918085 -0.724300981182845 0.469501226111308 EIF1B-AS1 other 1 1 1 3.12622953115527 -0.724300981182845 0.282790502733604 16.4679625016084 12.5665454327239 1.31046058678346 0.191141495673962 29.7438488406165 21.1297063888317 1.40767923099669 0.160363687398771 JAKMIP2-AS1 other 1 1 1 1.31046058678346 1.40767923099669 1.24859917502088e-12 186.355598852948 42.7732928907464 4.35682142426927 1.88854350468966e-05 -295.206234824487 84.8525043838638 -3.47905152556258 0.00058809341602248 PAGR1 other 1.53303006709063e-08 1 0.189609767870842 4.35682142426927 -3.47905152556258 1.43376362956446e-11 73.442548858425 12.6846916131057 5.78985686830137 1.98043713986983e-08 -43.2040279614818 28.2635477888078 -1.52861304901681 0.127548652924633 LINC00294 other 1.69198445924902e-07 1 0.000242266875320276 5.78985686830137 -1.52861304901681 4.77549441445013e-76 494.041105340568 20.5289445193321 24.0655872431887 3.07739904224944e-69 3.51856769104656 55.7817235229878 0.0630774287495177 0.949751346734915 CTBP1-AS other 7.6226441843453e-72 1 4.91091339162165e-65 24.0655872431887 0.0630774287495177 0.000875542532832946 -1.35207109836136 1.87026345600298 -0.722930822404526 0.470341272780786 -11.9074035498592 3.35247202863212 -3.5518278596101 0.000450490903109984 LINC00921 other 1 1 1 -0.722930822404526 -3.5518278596101 4.06586789705713e-07 2.58144116023673 3.473557592566 0.743169241172638 0.458025367453052 -23.4245976611464 5.38590495143933 -4.34924081883146 1.9382197404325e-05 N4BP2L2-IT2 other 0.00374059846529256 0.296140594140682 1 0.743169241172638 -4.34924081883146 0.189657193697476 -5.63173435123186 3.10608468212258 -1.81312968820391 0.0709099631678953 -3.00610432973731 8.01932610922935 -0.374857474155792 0.708057504983327 TRG-AS1 other 1 1 1 -1.81312968820391 -0.374857474155792 0.373517603198239 1.35091370490219 1.77926756650188 0.759252700569452 0.448363750666497 -2.59370156036242 3.33256612177159 -0.778289601943026 0.437079804396936 NPTN-IT1 other 1 1 1 0.759252700569452 -0.778289601943026 5.71403632474238e-06 4.41315957084922 1.21086296843933 3.64463996825115 0.000321105287301712 -5.44440497185717 3.14289520110079 -1.7322896958035 0.0843639848976776 GHET1 other 0.0477407734932225 1 1 3.64463996825115 -1.7322896958035 5.85177840686852e-15 26.5968674138269 4.00973375973406 6.63307566225817 1.76782563768742e-10 -17.7490411972062 7.98848999156567 -2.22182680530937 0.027118018047317 SLFNL1-AS1 other 7.72727338626989e-11 1 2.34555105608367e-06 6.63307566225817 -2.22182680530937 0.0858070207708619 2.05108069164263 1.65301204926711 1.24081412023101 0.215743562125538 -5.2460806916427 3.92104307275397 -1.33792988097886 0.182036780356264 RASSF1-AS1 other 1 1 1 1.24081412023101 -1.33792988097886 1.09976170270046e-06 100.520472120473 27.5639273963995 3.64681239632067 0.000322322876590963 -398.838746438747 124.810662367599 -3.19555027489611 0.00157294650305312 ABALON other 0.00976258463487199 1 1 3.64681239632067 -3.19555027489611 0.279222873530791 -11.5550491680502 7.71111900368675 -1.49849187420471 0.1351694226187 -0.551089099909729 15.1389592049684 -0.0364020466961076 0.970988581475092 PANDAR other 1 1 1 -1.49849187420471 -0.0364020466961076 0.413278084139798 9.40156165762132 20.9698456003383 0.448337190306715 0.654265481860661 -69.1605542177336 57.8307293856164 -1.19591357315537 0.232767975120156 TGFB2-OT1 other 1 1 1 0.448337190306715 -1.19591357315537 2.01374441136916e-34 568.554933214258 49.4820612710928 11.490122250554 5.13761224871376e-25 -268.549283606429 123.184976125289 -2.18004899666736 0.0301440946702778 EBLN3P other 3.17869555334622e-30 1 8.03060170596448e-21 11.490122250554 -2.18004899666736 0.000210719020899683 11.6769572966628 6.89001163896036 1.69476597552233 0.0912685390596033 -49.8439016968312 16.3290819502755 -3.05246197236399 0.00249523115961694 RBM5-AS1 other 1 1 1 1.69476597552233 -3.05246197236399 0.0833235878662774 -72.5178549834694 45.3962202153306 -1.59744257648525 0.111323883045666 -239.738165605342 114.78961989714 -2.08850038723158 0.037679156351013 GIMAP1-GIMAP5 other 1 1 1 -1.59744257648525 -2.08850038723158 0.0206786163376471 4.79749409201112 3.29562326782326 1.45571678014637 0.146971385323744 -7.10360464045673 5.38774452212599 -1.31847466250194 0.188787827261688 LINC02246 other 1 1 1 1.45571678014637 -1.31847466250194 0.00169499984048878 60.2101505724417 57.5252529710878 1.04667337321756 0.296196842632682 -300.763173827317 119.28722984854 -2.52133588992886 0.0122736529836561 TMEM265 other 1 1 1 1.04667337321756 -2.52133588992886 0.641954040713504 1.74921155149244 1.85810993015714 0.941392930042902 0.347338852462464 1.77038833066847 7.3023962906208 0.24243936650526 0.80862243715166 PEG13 other 1 1 1 0.941392930042902 0.24243936650526 0.422934577392835 -6.41411632471566 8.76858244388793 -0.731488398011992 0.465108299396986 4.99748004433388 12.8854137123914 0.387840092361799 0.698436603928964 ADORA3 other 1 1 1 -0.731488398011992 0.387840092361799 0.0346293268275517 20.4349251140126 11.8079065442958 1.73061372372432 0.084650658746681 -26.0254451036677 26.6834733810568 -0.975339481933554 0.330255335034987 BISPR other 1 1 1 1.73061372372432 -0.975339481933554 0.786255755662858 -1.41565184102363 6.07279281028154 -0.233113805336296 0.815857159097916 -17.490824074389 25.7365765334772 -0.679609584112229 0.497358635574067 PRNCR1 other 1 1 1 -0.233113805336296 -0.679609584112229 1.37322055506228e-16 179.793849095042 23.6883770657128 7.5899606206151 5.07816360121109e-13 -143.395374826537 64.1088728575833 -2.23674771423743 0.0261104227796027 PCBP2-OT1 other 1.88845290732165e-12 1 7.20083598651733e-09 7.5899606206151 -2.23674771423743 2.92990623315902e-10 36.2792123994327 9.57500368914144 3.78895022678427 0.000186570515414157 -34.3383742995859 14.0691391010333 -2.44068766773825 0.0153024145068464 GTF2IP12 other 3.25826237288204e-06 1 1 3.78895022678427 -2.44068766773825 9.26501614362629e-09 125.241006738292 20.050631966251 6.24623737292151 1.73248560913117e-09 -67.0442597766072 134.020577398201 -0.500253476579239 0.617324694028634 IQCJ-SCHIP1 other 9.4605079842568e-05 1 2.21827457393154e-05 6.24623737292151 -0.500253476579239 1.46563300419941e-06 4.29193778411623 1.02188747366309 4.20001017208988 3.64484789400685e-05 -3.74869925811072 2.21631854177497 -1.69140815611664 0.0919300540184262 ARL17A other 0.012877051574896 1 0.35679416034433 4.20001017208988 -1.69140815611664 8.90108142373452e-08 16.632687819 2.93625836170808 5.66458593559334 3.79513310392717e-08 -5.08898670716503 11.2070672417178 -0.45408728237317 0.650133530507921 TXNRD3NB other 0.000855037881563938 1 0.000457920760319852 5.66458593559334 -0.45408728237317 0.124902267340648 3.08463658318883 3.0857992470123 0.999623221172084 0.318387901451226 27.1757047854438 13.998252986261 1.94136402679078 0.0532544896302151 MIR1244-3 other 1 1 1 0.999623221172084 1.94136402679078 0.294229032233892 3.09662836959035 3.91638927437644 0.790684518990617 0.429816965071942 25.6906138578906 17.1543174678435 1.49761795571574 0.135392087119993 MIR1244-4 other 1 1 1 0.790684518990617 1.49761795571574 0.377415890076178 102.582441430331 75.0299829685728 1.3672193084903 0.172685364730741 112.608010761123 123.580840690833 0.911209295321422 0.362991935076051 MIR1244-2 other 1 1 1 1.3672193084903 0.911209295321422 1.75052130615342e-05 5.24994084236541 1.95983065504526 2.67877269337037 0.00783930943951295 -6.51445117774494 3.11327212189115 -2.09247727878916 0.0373226538368043 LINC02341 other 0.140514345244935 1 1 2.67877269337037 -2.09247727878916 0.00515877755007721 5.16093789607098 2.27278444219895 2.27075555439728 0.023946698094938 -8.6119476130122 5.98107191515894 -1.4398669227142 0.15105922048848 ZCWPW2 other 1 1 1 2.27075555439728 -1.4398669227142 0.41176435087486 7.92788635214215 6.02598931537159 1.3156157333235 0.189406825100307 10.2545697565202 15.6624209549181 0.65472443794203 0.513196420669074 LINC02009 other 1 1 1 1.3156157333235 0.65472443794203 0.305477170537838 -65.5521098118961 46.98287409937 -1.39523413729973 0.164087561019247 -99.0273512963902 73.0113154256563 -1.35632881997893 0.176123486115375 WDFY4 other 1 1 1 -1.39523413729973 -1.35632881997893