model_p beta_cntot stde_cntot t_val_cntot pval_cntot beta_loh stde_loh tval_loh pval_loh gene class fdr_model fdr_loh fdr_cntot ass_coeff_CN ass_coeff_LOH 0.076713845975594 -31.23475752596 29.6253328874094 -1.05432595963283 0.292316276635291 -74.8207300444033 38.0532830099892 -1.96620959155515 0.0499069667637514 FGR other 1 1 1 -1.05432595963283 -1.96620959155515 0.830360820075539 -38.7689386735046 114.194262783138 -0.339499881418115 0.734396284764389 -83.505973417073 144.988066681415 -0.575950664964464 0.564945011078316 FUCA2 other 1 1 1 -0.339499881418115 -0.575950664964464 0.0111705176605734 100.636542287944 198.154232272061 0.507869759500127 0.611802099347067 -1093.56555470945 444.479622043873 -2.46032776414102 0.0142687494427473 GCLC other 1 1 1 0.507869759500127 -2.46032776414102 1.61617575260231e-05 -41.9347713397063 48.6765519238324 -0.861498394654669 0.389436061156402 -527.729063471949 113.459412608596 -4.65125855439134 4.37823445624174e-06 NFYA other 0.0880007697291958 0.0376922204337852 1 -0.861498394654669 -4.65125855439134 0.0474909574648638 58.5842383780766 30.0858881088889 1.94723314020329 0.0521455003928733 32.0500808837485 38.6284493626983 0.829701461293907 0.407159559326067 STPG1 other 1 1 1 1.94723314020329 0.829701461293907 0.366010382342683 -265.502021658386 206.849901749091 -1.28354917944529 0.199978384993531 -202.418506793708 265.582685359823 -0.762167558172939 0.446370227928298 NIPAL3 other 1 1 1 -1.28354917944529 -0.762167558172939 0.724431243591832 57.8761216095549 102.472069352501 0.564798993279454 0.572500295134793 -73.344112739143 237.093616414534 -0.309346636355271 0.757205300292984 ENPP4 other 1 1 1 0.564798993279454 -0.309346636355271 0.000999467861188712 -39.7919999999996 45.706768124133 -0.870593166682235 0.384457610397194 168.474434782607 69.9124505445134 2.40979158176324 0.0163768559673132 SEMA3F other 1 1 1 -0.870593166682235 2.40979158176324 0.0315363187156098 412.497434990271 330.779020710736 1.24704835906446 0.213049235858937 -670.427070240608 538.519000094728 -1.24494599099136 0.213820323509832 LAP3 other 1 1 1 1.24704835906446 -1.24494599099136 3.07026976366382e-09 664.63871797278 107.107804095133 6.20532484619376 1.27078507672932e-09 387.831130151305 170.143414238412 2.27943662637367 0.0231235248751593 HS3ST1 other 2.14427640294281e-05 1 1.19707954227902e-05 6.20532484619376 2.27943662637367 1.18787450605316e-27 277.02740934087 23.9908079705834 11.5472313262875 4.2077324732223e-27 -44.2652568358643 89.3242367517729 -0.495557067662106 0.620456054747323 MAD1L1 other 1.0658797942815e-23 1 4.13409715494091e-23 11.5472313262875 -0.495557067662106 0.693278357249516 99.1161786533603 253.113679924193 0.391587600808638 0.695553824766721 -397.49041964647 593.867683397532 -0.66932488626493 0.503641714331851 LASP1 other 1 1 1 0.391587600808638 -0.66932488626493 2.25070272293334e-06 117.357401839407 22.9885583156498 5.1050353061729 4.94528430192538e-07 6.58918866771764 51.9123461404222 0.126929124911711 0.899054876412058 SNX11 other 0.0132813967680297 1 0.00446756983835939 5.1050353061729 0.126929124911711 0.733101638696709 -3.2263713001818 102.230051390502 -0.0315599107727883 0.974837455791286 -153.568091506667 210.721459728161 -0.728772910479909 0.466531847336969 DBNDD1 other 1 1 1 -0.0315599107727883 -0.728772910479909 0.000293824124430932 231.23977981652 272.58873344737 0.848310114992947 0.396732906159324 -1123.32512804147 416.94801729087 -2.69416109792367 0.00733029135024636 RBM5 other 1 1 1 0.848310114992947 -2.69416109792367 0.0699958754002699 179.309086979492 130.480711403816 1.37421910909545 0.170079651693055 -396.959760178024 276.310804859955 -1.43664219131502 0.151536848818236 SARM1 other 1 1 1 1.37421910909545 -1.43664219131502 9.2974546939541e-07 365.018995245184 96.3971980931889 3.7866141595974 0.000174119970667532 -543.99630981541 204.134290078638 -2.66489431837174 0.00798701933422041 POLDIP2 other 0.00564820372657711 1 1 3.7866141595974 -2.66489431837174 0.478135391767744 -174.540603888047 245.049029469346 -0.71226808882294 0.476679748511742 -598.973577435938 500.672592933019 -1.19633785809416 0.232214897233457 PLXND1 other 1 1 1 -0.71226808882294 -1.19633785809416 1.85415643587098e-80 259.04041496866 65.7195237181698 3.94160517777827 9.42563539385068e-05 -789.836079259156 84.4605578394848 -9.35153756337035 4.55748595609176e-19 AK2 other 1.82096703566889e-76 4.46633623696992e-15 0.784212864768377 3.94160517777827 -9.35153756337035 0.00392915236424273 -627.826265816214 286.990973904041 -2.18761676465176 0.0292278418013955 -1535.92728179345 461.336705777684 -3.32929780474396 0.000944585667098949 CD38 other 1 1 1 -2.18761676465176 -3.32929780474396 2.46534660626822e-44 676.077508027574 166.065717660811 4.07114434906102 5.55789561864383e-05 -1014.20326879928 212.461651739508 -4.77358271714258 2.47613256155757e-06 KDM1A other 2.32679412699595e-40 0.0215250203576199 0.467808074221251 4.07114434906102 -4.77358271714258 0.0113635799836544 -209.987596330266 274.276496619674 -0.765605507282841 0.444327221846722 -1171.74474351813 419.529596872129 -2.79299661395588 0.00545319024336471 RBM6 other 1 1 1 -0.765605507282841 -2.79299661395588 0.127429862011043 -153.433979931726 176.228323531843 -0.870654483097332 0.384419763925425 -228.933905643166 128.428782011474 -1.78257476289632 0.0753480847623053 CAMKK1 other 1 1 1 -0.870654483097332 -1.78257476289632 4.80875317620511e-05 455.246398362831 391.782758436735 1.16198681172016 0.245877964113615 -706.130369782424 517.607500419398 -1.36421974026704 0.173203800547202 HSPB6 other 0.247698876106325 1 1 1.16198681172016 -1.36421974026704 0.00176308661749321 169.851023834144 124.464637001858 1.36465286787932 0.173067661871058 -104.579251800008 164.409746620392 -0.636089124578923 0.525052857663866 ARHGAP33 other 1 1 1 1.36465286787932 -0.636089124578923 0.936146858359517 -41.7225594659532 136.468878724339 -0.305729481006662 0.759956877486404 -5.95357651561025 206.544654994597 -0.0288246457685675 0.977017663904774 ZMYND10 other 1 1 1 -0.305729481006662 -0.0288246457685675 8.34547670583261e-06 207.283773840685 49.0115246569954 4.22928638297523 2.85849860982568e-05 -205.152290534184 114.759388499498 -1.78767326330848 0.0745231413381012 CDC27 essential 0.0468097788430151 1 0.243658421501541 4.22928638297523 -1.78767326330848 7.86445189597372e-05 250.752905396224 63.8875378178899 3.92491108533546 0.000100729188537209 -101.043156177789 47.7560227586289 -2.11582016970901 0.0349238410041506 DVL2 other 0.394716840658921 1 0.836858098367131 3.92491108533546 -2.11582016970901 0.354396974253438 40.6111695137975 54.5003438567065 0.745154372247141 0.456578056758172 -35.9682560540647 76.6126977110019 -0.469481654199725 0.638959020379947 MCUB other 1 1 1 0.745154372247141 -0.469481654199725 0.00342120643391079 104.884410029276 49.5402699915393 2.11715459054197 0.0348098158045979 -100.281038117918 36.4193830489244 -2.75350732831484 0.00614130711740255 DHX33 essential 1 1 1 2.11715459054197 -2.75350732831484 8.09561372105575e-08 269.553636489417 49.567656434752 5.43809523946815 8.96817572657772e-08 -64.2416178573078 106.788268912582 -0.601579354281854 0.547765410202522 LIG3 other 0.000525324374359308 1 0.000821215851282721 5.43809523946815 -0.601579354281854 1.85452296109637e-05 63.6550108517739 36.3522371715146 1.75106171736945 0.080638493333157 -134.889664831638 55.5128618225668 -2.4298812996307 0.0155065098251522 RPAP3 essential 0.100311146965703 1 1 1.75106171736945 -2.4298812996307 5.55878829275918e-11 287.421526199449 48.1375508163467 5.97083817778792 4.88330592739317e-09 -162.390391979825 112.712998304145 -1.44074236710154 0.150371937768069 CIAPIN1 essential 4.117950367276e-07 1 4.56784436448358e-05 5.97083817778792 -1.44074236710154 9.49363377066823e-06 123.939306129531 47.4087563024456 2.61427035416953 0.00925213900010734 -111.871678777024 55.3265794121831 -2.02202413316718 0.0437854666761181 FAM214B other 0.0529270082714754 1 1 2.61427035416953 -2.02202413316718 0.925442741428995 -0.706402546870138 36.8602927964155 -0.0191643227245019 0.984718765473904 -32.4381773161401 83.2372457729195 -0.38970748028635 0.696942719558353 COPZ2 other 1 1 1 -0.0191643227245019 -0.38970748028635 7.1451501518895e-10 -32.6643346580759 87.980609861229 -0.37126742710237 0.710618283175142 -588.023146498559 121.374338924042 -4.84470730560729 1.76380189954679e-06 IBTK other 5.11664202376807e-06 0.0154244476115366 1 -0.37126742710237 -4.84470730560729 4.45273373735973e-16 224.294032955592 48.320725430039 4.64177702133913 4.57985620562243e-06 -70.0555225787126 55.9812363508709 -1.25141077877646 0.21145719916437 ZNF195 other 3.64233619716026e-12 1 0.0402844151846549 4.64177702133913 -1.25141077877646 3.07837687448454e-06 91.3973169591115 325.825462251938 0.28051005077203 0.779220187994256 -1165.09245020102 379.324059426309 -3.07149631363512 0.00226414591451881 MYCBP2 other 0.0179500155551193 1 1 0.28051005077203 -3.07149631363512 7.24752432353366e-20 222.764850294236 97.5218521630479 2.28425573708129 0.0228385773034164 -499.094162893692 113.378777848429 -4.40200690433362 1.35193175958724e-05 FBXL3 other 6.17778973338009e-16 0.113670422346095 1 2.28425573708129 -4.40200690433362 0.0801243778525166 -13.9691139262281 88.8288061960351 -0.157258827675786 0.875113333161537 -474.566310553243 211.388466268587 -2.24499623338137 0.0252666205915557 PDK2 other 1 1 1 -0.157258827675786 -2.24499623338137 0.0214058894713984 378.617893303437 286.657281194489 1.32080333604558 0.187256607258851 1792.20749513512 682.166580992853 2.62722851730242 0.00891036629646493 ITGA3 other 1 1 1 1.32080333604558 2.62722851730242 0.150253674502681 5.87741935483906 6.64434085110668 0.884575232750157 0.376872196471324 -22.4107526881721 15.0327842739881 -1.49079187725393 0.1367375833452 ITGA2B other 1 1 1 0.884575232750157 -1.49079187725393 3.40685075582056e-05 168.966483905203 39.156423481703 4.31516642433283 1.9741317460558e-05 -63.2917644788881 88.4223265109814 -0.715789404964681 0.474503682363699 OSBPL7 other 0.179132212741045 1 0.169380503811588 4.31516642433283 -0.715789404964681 0.000144076763547459 437.037548664834 103.855623516772 4.20812599131191 3.12677528697161e-05 381.180498674582 215.547640653758 1.7684280724134 0.0776869699897139 TMEM98 other 0.700213070840648 1 0.266039096355971 4.20812599131191 1.7684280724134 0.000736289944220213 -7.21916202256355 3.98223158039885 -1.81284334595139 0.0705404248986209 -9.84402609759411 2.97672360649975 -3.30700037991416 0.00102069049884472 YBX2 other 1 1 1 -1.81284334595139 -3.30700037991416 0.190932791579866 86.4810893955848 47.6643485697659 1.81437682441003 0.0703053020419742 51.0163952225845 110.676041658849 0.460952474066963 0.645062022285541 MAP3K14 other 1 1 1 1.81437682441003 0.460952474066963 0.00235868671383434 96.6810171802469 256.845722866683 0.376416691316403 0.706790245253114 -744.319304123569 319.303680328864 -2.33107023181494 0.0202046801349696 ABCC8 other 1 1 1 0.376416691316403 -2.33107023181494 0.0784501448974687 -634.168394168153 450.709311270989 -1.40704524692382 0.160123154669399 1338.09064983238 1091.77289967111 1.22561262533213 0.221003080674851 TMEM132A other 1 1 1 -1.40704524692382 1.22561262533213 0.00312560523023075 430.247818974881 630.892728666091 0.681966679001931 0.495621303435344 -4195.10169029447 1370.59556506117 -3.06078743958816 0.00234362552907866 AP2B1 other 1 1 1 0.681966679001931 -3.06078743958816 0.0717295986759602 -399.596134663353 265.958434090892 -1.50247588887062 0.133696503354414 -1379.68969243558 644.080928254968 -2.14210611106531 0.0327370151076177 CX3CL1 other 1 1 1 -1.50247588887062 -2.14210611106531 0.0216368560615237 -127.064515631265 105.296684255858 -1.20672855493259 0.228188030950201 -280.61967256118 119.945224207441 -2.3395652008275 0.0197546476564353 MAP3K9 other 1 1 1 -1.20672855493259 -2.3395652008275 3.49820921387819e-06 30.4478690549738 75.1402434358851 0.405213872922225 0.68551815105777 -354.356199112808 110.009584804876 -3.22113931928141 0.00137198775845812 FARP2 other 0.0203175991142045 1 1 0.405213872922225 -3.22113931928141 0.00995973592718684 -603.793444013472 310.84815834169 -1.94240637369249 0.052729992565385 -1180.2883558842 386.991113143928 -3.04991074935934 0.00242832093888739 USH1C other 1 1 1 -1.94240637369249 -3.04991074935934 0.0169835110026155 20.0721958705361 7.87942472624131 2.54741895099124 0.011193880794091 -8.92986886160694 21.7871171723243 -0.409869226432139 0.682102726244261 TBXA2R other 1 1 1 2.54741895099124 -0.409869226432139 2.68183486499811e-09 30.9078939196326 11.7955662509274 2.62029759844742 0.00909060875967175 -52.9047171194421 8.82880234689432 -5.99228695362653 4.32354418398542e-09 COX10 other 1.87916168990418e-05 4.01441077483046e-05 1 2.62029759844742 -5.99228695362653 1.73429895080472e-60 757.597719374107 83.6211787929773 9.05987849381683 4.36478186769186e-18 -333.401912266371 118.302721698495 -2.81820999111141 0.00504792079449025 PAF1 essential 1.67932167406421e-56 1 4.2552258428128e-14 9.05987849381683 -2.81820999111141 0.00400527649108971 -126.998757841129 77.7750332497989 -1.63289879199708 0.103208910201685 -164.898005659006 58.2134321895414 -2.83264530979898 0.00482947952508033 ARHGAP44 other 1 1 1 -1.63289879199708 -2.83264530979898 1.54878529920417e-06 249.241537792684 54.286614033942 4.59121538943006 5.76602716560074e-06 -112.876384067074 40.6327068316986 -2.7779686087518 0.00570499869780875 ELAC2 essential 0.00924469945094967 1 0.0505276960521593 4.59121538943006 -2.7779686087518 2.59330158258225e-26 198.584327912409 70.1859159854569 2.82940423479773 0.00487875757259437 -252.151241494792 87.1047699008409 -2.89480405931659 0.00398446957365094 MARK4 other 2.31011304976426e-22 1 1 2.82940423479773 -2.89480405931659 0.337932178197906 88.4702730939667 92.5239779648402 0.956187520683406 0.339507371220574 -57.2950133118843 148.731880376205 -0.385223485153024 0.700259704558578 PROM1 other 1 1 1 0.956187520683406 -0.385223485153024 3.19034269641393e-13 -4.86984566443537 6.20467145198867 -0.784867611785395 0.432959405281033 -40.8393802691509 8.25593003769212 -4.94667228073644 1.08147794780297e-06 CEACAM21 other 2.48495792623681e-09 0.00952133185245737 1 -0.784867611785395 -4.94667228073644 0.0287110240509036 56.9653141542197 317.129227477718 0.179628079717825 0.857527627657556 -618.351016025597 231.112227642816 -2.67554435493244 0.00774037980452333 PAFAH1B1 essential 1 1 1 0.179628079717825 -2.67554435493244 0.688488757800515 -49.7119014456551 94.0539263335902 -0.528546796327641 0.597388812317624 -159.01588140179 199.1720906935 -0.798384356202267 0.42508213113154 NOS2 other 1 1 1 -0.528546796327641 -0.798384356202267 0.0908956511449298 -80.5625440914094 94.962889736878 -0.848358177753763 0.396702967694905 -140.867487501781 71.1170862409132 -1.9807826072146 0.0482422081574938 DNAH9 other 1 1 1 -0.848358177753763 -1.9807826072146 0.0718439822106212 464.818812737137 202.345151365445 2.29715814587349 0.0220827713860529 318.113347101484 428.493614357014 0.742399271407663 0.458245227854275 KIAA0100 other 1 1 1 2.29715814587349 0.742399271407663 0.40306971458943 -502.545687177703 644.590236519382 -0.779635896893688 0.436027244271639 -515.833209896589 482.725541458338 -1.06858486985841 0.285846682455099 GAS7 other 1 1 1 -0.779635896893688 -1.06858486985841 1.75690253444943e-08 29.5467644184511 35.0784229940219 0.84230595039824 0.40007851395183 -93.2455560298279 43.5343461786802 -2.14188483840128 0.0327562001116936 TRAPPC6A other 0.000118555783024647 1 1 0.84230595039824 -2.14188483840128 0.133220219375478 -80.4365886449037 40.6345904659539 -1.97951025770269 0.0483856664052778 -111.885363163157 112.975854297525 -0.990347573460285 0.322552287935645 MATK other 1 1 1 -1.97951025770269 -0.990347573460285 3.44768014791007e-76 63.3313290989612 14.7910149132233 4.28174330635977 2.28027143157662e-05 -161.392102318398 18.9931042741656 -8.49740516287917 3.06421120923472e-16 ST7L other 3.37769224090749e-72 2.98668666564108e-12 0.195191234542958 4.28174330635977 -8.49740516287917 1.41414498471876e-05 -69.6571349811633 128.156962543324 -0.543529852758607 0.58704283317628 -639.006128824774 160.687517869566 -3.97670047615939 8.17947188007645e-05 PAX6 other 0.0774810037127409 0.655093902875323 1 -0.543529852758607 -3.97670047615939 0.000931978291807788 -11.551268179067 40.0708409662506 -0.288271169272339 0.773276478176505 -191.85704941283 60.6469262448884 -3.16350821537308 0.00166807877755093 CACNA2D2 other 1 1 1 -0.288271169272339 -3.16350821537308 0.0363706269740008 30.8846104914973 19.5678578747028 1.57833374962442 0.115210860154194 114.569073971984 45.9409111084495 2.49383547708769 0.013004938882557 TEAD3 other 1 1 1 1.57833374962442 2.49383547708769 1.71601829293046e-68 247.750412119513 45.7654402776669 5.4134825452649 1.02042119100709e-07 -362.549383420775 58.5095114486613 -6.19641788906221 1.3337736281487e-09 DNAJC11 essential 1.67363264109508e-64 1.2476118517703e-05 0.000933481305533282 5.4134825452649 -6.19641788906221 0.0342348732768004 44.9171417137937 32.1496680766787 1.3971261416032 0.163086259392693 -76.4618187950037 60.6654238018029 -1.26038547171134 0.208204460032329 MYLIP other 1 1 1 1.3971261416032 -1.26038547171134 1.05719247315391e-16 201.898695943877 32.4167294408133 6.22822534619061 1.10936877597515e-09 76.8477759955928 41.4384664943985 1.85450337564931 0.0643406123638712 E2F2 other 8.72289509599288e-13 1 1.04558007135658e-05 6.22822534619061 1.85450337564931 6.17181085814165e-14 426.342282868178 173.763821838707 2.45357335236285 0.0145357235465984 -642.881760042436 224.413086073935 -2.86472491996582 0.00437585286557244 PSMB1 essential 4.87696494010353e-10 1 1 2.45357335236285 -2.86472491996582 7.19892818078469e-06 41.7165327841064 56.4844790225666 0.738548597880134 0.460579423416536 -414.273382366535 105.802598042166 -3.91553128214708 0.000104692643806175 JARID2 other 0.0405461996037851 0.831364284464839 1 0.738548597880134 -3.91553128214708 6.77134833352406e-61 242.867634613419 43.7731277319198 5.54832718604929 5.00060867690633e-08 -358.965942358999 58.0538932100109 -6.18332247004405 1.43964759895387e-09 CDK11A other 6.56008226551811e-57 1.34563861074219e-05 0.000459955986101844 5.54832718604929 -6.18332247004405 1.06420712947714e-96 319.284631060728 63.3328542803308 5.04137441283596 6.77756930585303e-07 -822.157434735918 80.9226879952924 -10.1597889924732 6.46241538520234e-22 NADK other 1.04781833968319e-92 6.34932311596129e-18 0.00610523443071241 5.04137441283596 -10.1597889924732 1.85063473947699e-05 219.426768019547 75.5058442665701 2.90608985504314 0.00384534050788873 -194.43498785877 128.446065082677 -1.51374810690867 0.130810972280248 DLEC1 other 0.100119339405705 1 1 2.90608985504314 -1.51374810690867 4.97727751587938e-12 102.265959697796 23.4486716455914 4.36126878500696 1.61382933950762e-05 -84.4819088159517 37.6891261347163 -2.24154597042073 0.0254907773234763 SS18L2 essential 3.77825136230404e-08 1 0.139015259305186 4.36126878500696 -2.24154597042073 0.000287739025765175 107.968618054347 29.1671203210418 3.701723614328 0.00024145064412013 -43.9005635370056 80.4597351920889 -0.545621526496424 0.585603882281746 MPND other 1 1 1 3.701723614328 -0.545621526496424 5.52082763162666e-05 9.99212243979427 58.9225086081297 0.169580737070241 0.865418165906319 -350.488572422399 98.5610473025079 -3.55605568340466 0.000417491521838055 CRY1 other 0.282611166462969 1 1 0.169580737070241 -3.55605568340466 1.47107862756564e-07 -181.521209656465 314.198636106862 -0.57772755447203 0.563746304694659 -2138.00144975015 461.471370313242 -4.63300994880549 4.76569436526577e-06 MAPK8IP2 other 0.000938989487975148 0.0409706744581898 1 -0.57772755447203 -4.63300994880549 6.18558214510859e-85 1066.71370200493 363.605976023203 2.9337078385556 0.003525280958318 -4994.84357161455 464.667724664783 -10.7492801984857 4.46147624548832e-24 CSDE1 other 6.08166436507076e-81 4.38786188743776e-20 1 2.9337078385556 -10.7492801984857 1.01019713889629e-05 330.551452258652 241.099379512577 1.37101743242524 0.171071588207965 -693.203051820514 328.938214287047 -2.1073959233438 0.0356510982388243 REV3L essential 0.0561366550084669 1 1 1.37101743242524 -2.1073959233438 4.71926933115876e-15 9.34163822943033 6.56928184982986 1.4220181814352 0.155732665031095 -26.6894304340457 8.39413857986289 -3.17953178639107 0.00157980151853577 MASP2 other 3.79665217691723e-11 1 1 1.4220181814352 -3.17953178639107 3.5712675239484e-49 74.888283626447 18.477464889736 4.05295228936122 5.98674984449135e-05 -128.596807803922 23.7340185654113 -5.41824838678318 9.96360704237858e-08 FAM76A other 3.40377507707522e-45 0.000903898430884584 0.503066589432608 4.05295228936122 -5.41824838678318 7.15628875391522e-22 112.200268458266 92.0902245283647 1.21837327504514 0.223738008786341 -487.683148973252 106.29784485029 -4.5878931003738 5.85423829976061e-06 POMT2 other 6.22024618490311e-18 0.0501239883225503 1 1.21837327504514 -4.5878931003738 3.04744864059992e-27 -3.13418066634323 90.310030098356 -0.0347046796787668 0.972331039294086 -821.498389743774 114.65210017549 -7.16514035492037 3.31679077772673e-12 VTA1 other 2.72959974738535e-23 3.1774855650622e-08 1 -0.0347046796787668 -7.16514035492037 1.38739013443081e-06 126.535953890615 74.3148158922821 1.70270157264504 0.0893366513877609 -448.599931204274 131.593071386894 -3.40899354712494 0.000712657709604174 RANBP9 other 0.00831046690524057 1 1 1.70270157264504 -3.40899354712494 0.0110927474101142 -2.19011068232891 8.02157467062309 -0.273027525424605 0.78496073897704 50.3191199129245 18.8328457439025 2.67188085099758 0.00782399354764098 ETV7 other 1 1 1 -0.273027525424605 2.67188085099758 2.6022783404938e-11 590.787375533421 238.220083141933 2.48000658777969 0.0135155090093463 -1395.92024359886 370.859867929326 -3.76400997873644 0.000190153057910135 UQCRC1 essential 1.94286100901267e-07 1 1 2.48000658777969 -3.76400997873644 0.0262313994376634 127.773701504798 163.817463985138 0.779976068463557 0.435826233375421 -426.761005937047 263.30434220422 -1.62078985239844 0.105782368246645 HHATL other 1 1 1 0.779976068463557 -1.62078985239844 0.0767706332201739 12.5629888100109 9.16936028399708 1.37010526589697 0.171357516068685 4.1665077793102 11.2429201385432 0.370589466790439 0.711122892628731 GIPR other 1 1 1 1.37010526589697 0.370589466790439 4.56144793778536e-05 -5.58380681818159 7.56666600747025 -0.737948101934052 0.460942067634562 -46.3630149147724 11.5619937601307 -4.00994983016218 7.14172120085016e-05 PHF7 other 0.235918087342259 0.574480053396387 1 -0.737948101934052 -4.00994983016218 0.03380013567274 -112.953977272724 80.6494633269708 -1.40055460524 0.162056935342101 -320.996200284087 123.233745327697 -2.60477517282714 0.00950689818503857 SEMA3G other 1 1 1 -1.40055460524 -2.60477517282714 1.18427018771226e-11 327.241335227259 224.278535426288 1.45908450224748 0.145260250846106 -1659.50515210702 342.70139907985 -4.84242304397581 1.78315811455795e-06 NISCH other 8.91873878366099e-08 0.0155919345536947 1 1.45908450224748 -4.84242304397581 0.699009418623699 319.319176136381 492.380631619117 0.648520992969097 0.516988666649677 620.497416548311 752.365940926836 0.824728211093557 0.409975848256166 STAB1 other 1 1 1 0.648520992969097 0.824728211093557 1.53329565170213e-39 214.807116066233 54.6908152330301 3.92766345045269 9.96226486484935e-05 -208.11835215574 66.7946232379999 -3.11579498568591 0.00195510286529803 FUZ other 1.43010485434258e-35 1 0.828163078214927 3.92766345045269 -3.11579498568591 0.702497892727813 6.33816652561824 15.9268589462004 0.397954583953311 0.690858442616247 -6.59392086466025 18.5415117792162 -0.355630163450404 0.722289544681525 PRSS3 other 1 1 1 0.397954583953311 -0.355630163450404 0.000276026820334574 -13.8353607337398 17.4776310580147 -0.791603890013193 0.429020152474895 112.574033007753 34.8702266701484 3.22837112797218 0.00133855920283667 HFE other 1 1 1 -0.791603890013193 3.22837112797218 1.61120863472468e-50 81.7771328405059 32.5142708032942 2.51511508085922 0.0122563605553479 -295.685234835738 41.7539347919866 -7.08161365650469 5.71047594635966e-12 SCMH1 other 1.53934872961596e-46 5.4586439571252e-08 1 2.51511508085922 -7.08161365650469 1.27313205603504e-12 -199.141411089293 743.42030716613 -0.267871901224231 0.788924023394569 -5391.04906330259 1014.26784589132 -5.31521243145102 1.70057802261765e-07 FYN other 9.78656611474137e-09 0.00153307108738981 1 -0.267871901224231 -5.31521243145102 9.91405748312961e-07 -336.088906827092 181.861365242788 -1.84805005933178 0.0652705858793698 -1037.04351460735 230.902386056543 -4.49126374273758 9.07300980498062e-06 HIVEP2 other 0.00600891024052486 0.0769935612050655 1 -1.84805005933178 -4.49126374273758 6.63092532212969e-66 182.065747532958 59.5279487249218 3.05849187537576 0.00236127149430999 -634.516116089874 76.0948729643363 -8.33848709343736 9.89808215177032e-16 ELOA other 6.45520580109326e-62 9.63479316653323e-12 1 3.05849187537576 -8.33848709343736 5.22075517581439e-28 273.701192089469 59.5923537880359 4.59289111255778 5.72543956556426e-06 -155.7557011912 76.1772022768845 -2.04464979725913 0.0414880437052571 LYPLA2 other 4.69137060098681e-24 1 0.0501834777921707 4.59289111255778 -2.04464979725913 6.09095021883326e-09 10.4703974548858 90.7076003763082 0.115430211045694 0.908157033978296 -374.016114969007 115.897255506552 -3.22713521846825 0.00134421816295832 CLCN6 other 4.20153746095118e-05 1 1 0.115430211045694 -3.22713521846825 0.880520700676479 -40.3922892152406 84.1070418905399 -0.480248601155283 0.631290387757707 -55.4591721939179 158.029000219731 -0.350943004871288 0.725799841909251 SLC6A7 other 1 1 1 -0.480248601155283 -0.350943004871288 2.19405598609493e-15 30.9663581927049 64.2187076285299 0.482201516290679 0.629903671594982 -337.373932654171 75.7842295781694 -4.45176964299913 1.08197465489805e-05 BTBD7 other 1.7749912927508e-11 0.0915134163112768 1 0.482201516290679 -4.45176964299913 8.3793536129796e-15 144.137922713642 19.4735253576451 7.40173749059024 6.95984671918329e-13 -67.723423765037 54.1420040964312 -1.25084811497587 0.211659175710305 APBA3 other 6.71605192080315e-11 1 6.70511632926118e-09 7.40173749059024 -1.25084811497587 0.00409265795673496 -29.6995693464266 30.5650437890053 -0.97168417462271 0.331743980268346 -154.438837235354 49.1272942061743 -3.14364631170637 0.00178200214207267 ABHD5 other 1 1 1 -0.97168417462271 -3.14364631170637 0.00220487900930991 86.111498606151 66.2224609323448 1.30033673460317 0.194170941566094 -164.546973728474 49.1771691669384 -3.34600336936634 0.000890653122176201 TTC19 other 1 1 1 1.30033673460317 -3.34600336936634 0.0440279713650715 147.902173389849 59.1207693894905 2.50169568016719 0.0127246682094314 174.741708212513 79.5529440597029 2.19654608987661 0.0285773999815672 DPF1 other 1 1 1 2.50169568016719 2.19654608987661 0.134862559713051 -365.09381303275 247.410290561247 -1.47566138904141 0.140753311800985 -1055.77376574268 599.312780055075 -1.76164066724167 0.0788276353432942 SYT7 other 1 1 1 -1.47566138904141 -1.76164066724167 2.3771798267816e-10 -38.1099796334014 69.5239339728315 -0.548156260091582 0.583863869913705 -627.240218672956 109.411249362367 -5.73286771084712 1.84122538432207e-08 LARS2 essential 1.72820973407023e-06 0.00016944797211916 1 -0.548156260091582 -5.73286771084712 4.41553347513945e-09 35.6636465406643 197.996466736561 0.180122641219228 0.857139974704548 -1139.71940789098 247.881902764882 -4.59783225470888 5.60085815774047e-06 PIK3C2A other 3.05952314492413e-05 0.0479825518373626 1 0.180122641219228 -4.59783225470888 1.44538918414919e-06 48.3458704399311 43.3636270448741 1.11489452646342 0.265511189514828 -76.2823520202411 53.433138020046 -1.42762253625499 0.154118008326538 PLAUR other 0.00864487271039631 1 1 1.11489452646342 -1.42762253625499 0.708814013759234 104.378794675746 383.026300781214 0.272510776578154 0.785358022945417 -292.068561940078 617.646446800243 -0.472873378375538 0.636539610072445 DCN other 1 1 1 0.272510776578154 -0.472873378375538 7.33552828828349e-21 77.8570418722176 14.1131518155946 5.51663036644923 5.92794629705389e-08 15.8812810640208 17.304701075253 0.917743738823214 0.359259267180906 QPCTL other 6.32249183167154e-17 1 0.000544778264699253 5.51663036644923 0.917743738823214 8.10997918192562e-54 581.410261218974 104.247288917026 5.57722188518242 4.28919086741324e-08 -382.167028336882 127.21869946037 -3.00401615452712 0.0028175502851795 PPP5C other 7.79368999383052e-50 1 0.000394948695071412 5.57722188518242 -3.00401615452712 5.39877487984729e-21 -1.5683404596608 162.482460649745 -0.00965236772873341 0.992303069466816 -1172.80346350524 213.674975502824 -5.48872632719569 6.88990742998469e-08 TYROBP other 4.6596825987962e-17 0.000627394970574406 1 -0.00965236772873341 -5.48872632719569 9.34395474377981e-05 154.449749936564 36.3207570671334 4.25238245037368 2.59071796335785e-05 5.13642577085856 82.1765627689649 0.0625047531532725 0.950189586227793 BRCA1 ts 0.464955188050483 1 0.22124731407076 4.25238245037368 0.0625047531532725 7.72327860692647e-99 672.632415143386 92.2513547853094 7.2913012140446 1.45626818674235e-12 -700.531552218472 113.179625540967 -6.18955530971345 1.39329900417694e-09 ERCC1 ts 7.60742942782258e-95 1.30273456890544e-05 1.40107562246482e-08 7.2913012140446 -6.18955530971345 0.71961253206879 -974.658634538114 2145.23960260116 -0.454335559233717 0.649812906902629 -2768.99951000169 3416.10558700586 -0.810571991841931 0.418052707757621 LTF other 1 1 1 -0.454335559233717 -0.810571991841931 0.775967477663652 0.894578430482215 7.86797352311451 0.113698708804005 0.909528971358826 -7.22039802285913 13.6788660213768 -0.527850628230102 0.597871540737313 NR1H4 other 1 1 1 0.113698708804005 -0.527850628230102 0.024880188681385 -377.115625537354 250.986707765745 -1.50253226114799 0.133685278479037 -1522.3971726154 562.988111465555 -2.70413733720298 0.00711676580775161 ELOVL5 other 1 1 1 -1.50253226114799 -2.70413733720298 1.2913213855625e-06 4.57079981603854 70.4180702517749 0.0649094728057153 0.948275760269816 304.340284221253 91.120199937315 3.33998701090011 0.000909677266957279 ALOX5 other 0.00775180227753168 1 1 0.0649094728057153 3.33998701090011 2.02964537619725e-06 -113.688210227283 197.07106778857 -0.576889400879763 0.564311217179188 -1347.7176994555 301.127927917561 -4.47556528142572 9.73430456021947e-06 CALCOCO1 other 0.0120155006270877 0.0825274340615407 1 -0.576889400879763 -4.47556528142572 1.19670933732088e-20 1.31790963527525 106.220222033698 0.0124073327097466 0.990106284063649 -718.553775565747 125.350041906942 -5.73237762536361 1.84618196144298e-08 UBR7 other 1.02881101729476e-16 0.000169885664091983 1 0.0124073327097466 -5.73237762536361 1.41379715673706e-16 504.049451075103 144.484709416736 3.48860064923049 0.000534912214090469 -582.45930488957 190.242643555585 -3.06166532383885 0.0023372259350565 MAP4K5 other 1.16412057885729e-12 1 1 3.48860064923049 -3.06166532383885 3.24739509647475e-69 520.470414389474 65.2729736222724 7.97375062765456 1.36476420430308e-14 -422.381874230252 89.8291393126558 -4.70205856876939 3.46088061091078e-06 PSMC4 essential 3.16913287464971e-65 0.0299020084782691 1.32245651396969e-10 7.97375062765456 -4.70205856876939 4.58881775974267e-05 20.6227074705545 96.5786069147816 0.213532873680311 0.831010709372856 -547.390684666271 153.398306263381 -3.56842717498077 0.000398801894389123 MAN2B2 other 0.237195990001098 1 1 0.213532873680311 -3.56842717498077 0.000807043667063095 321.359386618235 95.7366155936971 3.35670301927189 0.000857570015885069 544.100722844567 216.602184760697 2.51198169328575 0.0123641255611823 SLC25A39 other 1 1 1 3.35670301927189 2.51198169328575 1.37876849472983e-20 -39.8342914896563 122.492979622233 -0.32519652646629 0.745187971016401 -1213.93613128684 168.986148742717 -7.18364280338184 2.9479548682769e-12 PGM3 other 1.18463789067187e-16 2.82590953673024e-08 1 -0.32519652646629 -7.18364280338184 3.90981151564602e-19 -10.2476188844745 27.7905594067746 -0.368744606198045 0.712496674806818 -265.628922845006 38.3386837355057 -6.92848311323233 1.5309743013441e-11 RWDD2A other 3.31473820296469e-15 1.45886541175079e-07 1 -0.368744606198045 -6.92848311323233 9.3790846191508e-07 26.2907329150129 22.0120655951637 1.19437827410388 0.232976428229068 -134.930998420624 37.291043600082 -3.61832186483318 0.000331099660002488 POLR3B essential 0.00569685599767219 1 1 1.19437827410388 -3.61832186483318 4.62613147542513e-13 22.5367329615072 151.930070352686 0.148336224087773 0.882145694396032 -712.699642226626 175.187511126298 -4.06821032871927 5.61925744149864e-05 ANGEL1 other 3.5898780249299e-09 0.45515985276139 1 0.148336224087773 -4.06821032871927 4.99163939597611e-06 46.4163884442412 60.806418413733 0.763346858030996 0.445669402303519 -509.397713240336 120.414299076715 -4.23037560444381 2.84523722696199e-05 RNF14 other 0.0286070853783391 0.235500285275644 1 0.763346858030996 -4.23037560444381 0.569109690363607 -5.93822508810482 7.19128142687229 -0.825753399931609 0.409393533470675 -15.652580422452 17.4197558812953 -0.898553374060726 0.36938428867167 CD6 other 1 1 1 -0.825753399931609 -0.898553374060726 0.0593977244917404 395.318710844324 165.826853833995 2.38392456773055 0.0175551064316171 361.141322184071 257.778467146223 1.40097552050077 0.161931102712964 TACC3 essential 1 1 1 2.38392456773055 1.40097552050077 1.713869693544e-13 0.590482657466971 72.2392751244017 0.00817398370138838 0.993481924490048 -559.610826520353 101.437726672655 -5.51679187691427 5.93693432728531e-08 UFL1 essential 1.34247413095302e-09 0.000541210933275329 1 0.00817398370138838 -5.51679187691427 5.91312615538322e-29 252.557173120752 22.5898041271052 11.1801400180231 1.07904867725879e-25 -69.3104988905736 66.2699234028956 -1.04588168103338 0.29619381831858 ZC3H3 other 5.33009191646243e-25 1 1.05919418159723e-21 11.1801400180231 -1.04588168103338 0.762272689213931 -3.91436936317361 5.97254928152993 -0.655393397134247 0.512559362292724 0.257024541685572 12.2025191125462 0.0210632361494365 0.983204825493657 ACPP other 1 1 1 -0.655393397134247 0.0210632361494365 9.24818982944233e-06 -51.3915296740033 119.54680344596 -0.429886272092874 0.667490268401352 -833.623609176184 194.614981994434 -4.28345033169146 2.26458445150278e-05 SLC30A9 other 0.0516233956279471 0.188141676230851 1 -0.429886272092874 -4.28345033169146 1.21925402426826e-51 41.6620058498687 52.6836445516103 0.790795819166525 0.429491124337657 -585.425957235903 63.5331213864856 -9.21450016086306 1.31406381621373e-18 COX15 essential 1.16755765363929e-47 1.28699410159973e-14 1 0.790795819166525 -9.21450016086306 7.43666066475158e-05 17.5605550020501 62.4779217033302 0.28106816813521 0.778791449074789 -165.076232198326 73.2467538152272 -2.25370031571294 0.0247109964171782 CCDC88C other 0.37451023107689 1 1 0.28106816813521 -2.25370031571294 2.28583203138406e-10 50.8985249537422 60.0830709583077 0.847135876078325 0.397392829359867 -429.841786853192 90.9369791856241 -4.72680960707725 3.09980621504408e-06 YAF2 other 1.66248563642563e-06 0.0268319225974216 1 0.847135876078325 -4.72680960707725 1.55705343662834e-40 827.52861541844 121.020842009051 6.83790165132506 2.79868191156832e-11 -2050.72400807624 258.306628927226 -7.93910716342476 1.82456973894555e-14 ZMYND11 other 1.45537784721651e-36 1.76855544795993e-10 2.67106201640081e-07 6.83790165132506 -7.93910716342476 0.813629859692328 17.3885534374198 30.9934317937214 0.561039950436927 0.575057861956407 33.8768337214994 65.8574855492688 0.51439609998708 0.607235123284438 DPEP1 other 1 1 1 0.561039950436927 0.51439609998708 8.71088471220811e-14 87.8572787143213 134.944650035073 0.651061592226786 0.515348140143011 -1348.36186643868 221.998219951097 -6.07375080185647 2.71420342786734e-09 BID other 6.86504824169121e-10 2.52665197100171e-05 1 0.651061592226786 -6.07375080185647 1.68172810117153e-06 77.9891511508542 128.56849559675 0.60659612441499 0.544433245684677 -755.722816791281 198.308172136143 -3.81085060010771 0.000158305029141095 CHDH other 0.0100180542986788 1 1 0.60659612441499 -3.81085060010771 0.396165172982297 -18.2914241925667 30.8523502254401 -0.59286971847882 0.553575019364328 10.6281931078006 39.2941143854622 0.270477990763236 0.786920242747525 IL20RA other 1 1 1 -0.59286971847882 0.270477990763236 0.7172593254987 -10.3859884939586 17.6125956493159 -0.589690963260265 0.555701913635416 -4.41417346082528 22.7251248660987 -0.194241989288707 0.846076462257888 CLCA4 other 1 1 1 -0.589690963260265 -0.194241989288707 4.14037134536348e-13 198.350785204863 62.8193944438283 3.15747687415586 0.00170140044549524 -372.263410862068 96.8946492609489 -3.8419398150616 0.000140105834899239 GLT8D1 other 3.21541238680927e-09 1 1 3.15747687415586 -3.8419398150616 0.639785063550967 -157.346611964712 169.478044062478 -0.928418857056826 0.353704028667315 -78.0149143270844 357.321443211371 -0.218332584873545 0.827272141847346 ATP2C1 other 1 1 1 -0.928418857056826 -0.218332584873545 0.306206202758502 23.3394946292231 45.4279579571957 0.513769398378298 0.607672897895904 118.293370648377 78.9748133503101 1.49786198447423 0.134891063351586 IGF1 other 1 1 1 0.513769398378298 1.49786198447423 1.1052981850388e-07 299.30807559924 132.012863636217 2.26726447222621 0.0238617804649582 -593.079591063287 218.035723631262 -2.72010283996531 0.00678642875613134 RALBP1 other 0.000709269845339401 1 1 2.26726447222621 -2.72010283996531 4.31274466546798e-05 85.0072136059616 365.423200752342 0.232626755583518 0.816159910184729 -1770.94185648624 543.167871338681 -3.26039508213475 0.0011993986051685 RUFY3 other 0.223745193244479 1 1 0.232626755583518 -3.26039508213475 0.00163733756783918 25.5129782771733 1335.90889290159 0.0190978429837077 0.984771993578801 -5633.21228188187 2022.19632772429 -2.78569009578872 0.00557981336653853 CNTN1 other 1 1 1 0.0190978429837077 -2.78569009578872 0.470245835863193 -190.508371476737 468.327496740755 -0.406784510417491 0.684365418995535 -1196.97344013489 977.520022289733 -1.22450017681593 0.221423282827612 WWTR1 other 1 1 1 -0.406784510417491 -1.22450017681593 1.00838883617021e-59 50.6021090705678 7.13377493856993 7.09331448024512 5.32517893952798e-12 -16.727660159472 8.90895981438995 -1.87762213636357 0.061100197917514 ZNF582 other 9.76019554529149e-56 1 5.11004171037105e-08 7.09331448024512 -1.87762213636357 1.51083932326152e-05 46.9799986861894 42.3022376386193 1.11057951798038 0.267368571741763 -182.762003501588 56.1429159077144 -3.25529945402204 0.0012220642118693 PRDM11 other 0.0825522606230095 1 1 1.11057951798038 -3.25529945402204 0.687727290697855 -162.617096082282 213.814733559126 -0.760551405300205 0.447340915942 -217.0446952106 283.771811519523 -0.764856431822395 0.444775617911838 SYT13 other 1 1 1 -0.760551405300205 -0.764856431822395 0.916300366256525 -1292.90187537471 6130.96529782837 -0.21088063829568 0.833078711145566 -4917.5474276829 11810.446403397 -0.416372697501805 0.677341724447697 CD74 other 1 1 1 -0.21088063829568 -0.416372697501805 2.40495495551956e-65 87.1790157732261 92.5922211734608 0.941537147163867 0.346949842007767 -1057.96049164283 107.506045199799 -9.84093954601919 8.97232640723156e-21 ZRANB1 other 2.34026166721608e-61 8.80903006661994e-17 1 0.941537147163867 -9.84093954601919 0.0225308915833808 -640.947375057136 915.411587143957 -0.700173980817594 0.484190387225689 988.833100425352 1175.47766873394 0.841218107946179 0.40068477795545 NCDN other 1 1 1 -0.700173980817594 0.841218107946179 6.48954501219902e-24 49.492755501412 29.3884598094569 1.68408810200682 0.0928819963724599 -152.974961768745 33.7711977581487 -4.52974640888577 7.63789652885979e-06 MNAT1 essential 5.7095017017327e-20 0.0650519647362988 1 1.68408810200682 -4.52974640888577 0.00644089412105223 74.1347339933069 374.812506345673 0.197791516393361 0.843300577387775 -864.770564774592 466.587443144093 -1.85339442259172 0.0645027348294437 SAMD4A other 1 1 1 0.197791516393361 -1.85339442259172 1.35656954889864e-07 35.8223269315648 15.4816137683624 2.31386259000788 0.0211372953868098 -16.7397889492294 19.8780947280554 -0.842122405504154 0.400179014028162 RUNX3 other 0.000866983598701122 1 1 2.31386259000788 -0.842122405504154 0.00528276137456139 45.1162890851028 60.2338244609075 0.749019168032138 0.454252348291456 322.609228479178 103.950275449517 3.10349565774698 0.00203782419612639 SERPINB1 other 1 1 1 0.749019168032138 3.10349565774698 0.0149798788070064 -210.060807430227 203.57534651352 -1.03185779136707 0.302709463964334 -550.328794562645 235.009313684062 -2.34173184856191 0.0196428280248498 NRXN3 other 1 1 1 -1.03185779136707 -2.34173184856191 5.6480742865549e-15 172.203471472469 68.2111806592487 2.52456371240248 0.0119380618836049 -249.178706087533 79.3855754923129 -3.13884108721567 0.0018113561506399 OSBPL5 other 4.53709807438955e-11 1 1 2.52456371240248 -3.13884108721567 9.97098363100989e-09 -12.328180089068 81.6420159925561 -0.151002886677763 0.88004311705615 -661.816733160142 130.847934795894 -5.05790736546581 6.250759181078e-07 AQR essential 6.80918472161666e-05 0.00555004907687916 1 -0.151002886677763 -5.05790736546581 0.718713693174817 -25.1578063452314 245.488789484347 -0.102480469263284 0.918422538474436 -337.351720663224 450.516475375942 -0.748811062640306 0.454375787701169 GABRA1 other 1 1 1 -0.102480469263284 -0.748811062640306 0.397984344829473 -10.6724412058153 12.5601289618754 -0.84970793199736 0.395952753588341 -4.23615679389832 15.6082001235032 -0.271405848232264 0.786207066202183 NLRP2 other 1 1 1 -0.84970793199736 -0.271405848232264 1.74938787998954e-14 980.392226243854 129.865899479398 7.54926605193527 2.57411982679633e-13 80.9806541456017 243.706232520258 0.332287989962957 0.739831133750701 RNF10 other 1.39461201792766e-10 1 2.48428304484114e-09 7.54926605193527 0.332287989962957 3.87369952720815e-28 51.41548056405 27.9075169475594 1.84235239060014 0.0661039994885601 -188.925479024132 33.0473258552352 -5.71681593396471 2.01867453659059e-08 ZNF839 other 3.48245587496013e-24 0.000185596936894139 1 1.84235239060014 -5.71681593396471 1.82340299615861e-17 49.8276699029136 33.0300913721426 1.50855380148715 0.132135459716376 -123.241394527802 37.8034749992464 -3.26005465186094 0.00120100792177635 ZDHHC6 other 1.51670661220474e-13 1 1 1.50855380148715 -3.26005465186094 3.09972424951877e-20 1382.69184020919 232.048311862717 5.95863779016505 5.23265119995925e-09 -4.89214543010807 269.319796085735 -0.0181648193011059 0.985515639634995 RNH1 other 2.65429387486293e-16 1 4.8914823417219e-05 5.95863779016505 -0.0181648193011059 6.81450071483358e-07 203.779898337854 41.1321804492804 4.95426928774496 1.03893518727657e-06 -17.8982235111897 90.2775408126015 -0.198257765442935 0.842935378952231 ERP44 other 0.00417797038826447 1 0.0093098982131853 4.95426928774496 -0.198257765442935 0.0166614287091092 46.3531249999983 70.7253997830748 0.655395729711958 0.512557862309721 -199.247851562501 108.069608222083 -1.84369921239139 0.0659038334971368 ALAS1 other 1 1 1 0.655395729711958 -1.84369921239139 4.14517667233388e-12 370.949396063427 307.694521808875 1.2055768620211 0.228633052065406 -1369.96171016217 368.833469661072 -3.71430963524284 0.000230158951492484 AKAP11 other 3.15282137697715e-08 1 1 1.2055768620211 -3.71430963524284 5.69165258084799e-07 42.2031791723657 25.6132522285131 1.64770872499293 0.100132886835592 -39.4670472979417 29.2385292063057 -1.34983011694822 0.177770858503035 SNAPC1 essential 0.00351402630341555 1 1 1.64770872499293 -1.34983011694822 0.000939354610703691 4.56152487591709 2.73105425663631 1.67024322743967 0.0955856546556504 -1.67792196913108 3.29347756930475 -0.509468163612024 0.610680688852055 ABCC2 other 1 1 1 1.67024322743967 -0.509468163612024 0.00195840696770821 79.6785759721805 34.4822150101916 2.31071513093432 0.0213122924407215 273.733478930778 80.9564534222027 3.38124346311477 0.000786300776000317 DEF6 other 1 1 1 2.31071513093432 3.38124346311477 1.97436615585241e-11 33.0301767312006 42.6706014827105 0.774073380347918 0.439305964770957 -176.552725269135 55.0770897017711 -3.20555654311302 0.00144689065110942 GCLM other 1.47840537750229e-07 1 1 0.774073380347918 -3.20555654311302 1.41905030335075e-06 36.7101580720404 44.7725416458133 0.81992571166603 0.412704414829951 -508.45732918718 111.458975877313 -4.56183385128944 6.59253380362644e-06 UBR2 other 0.00849159701525088 0.0562936461491662 1 0.81992571166603 -4.56183385128944 1.01045411644537e-18 888.312893440121 181.920691720318 4.88296787484625 1.46708542075749e-06 121.158565679801 221.978464683755 0.545812251888541 0.585472871474644 EHD2 other 8.53227455926469e-15 1 0.0130937373802606 4.88296787484625 0.545812251888541 1.15854444079268e-15 86.6338599671183 14.8616274557574 5.82936560783968 1.08056209473848e-08 28.8369880103667 19.0848943666799 1.510984942139 0.131513380985656 DEPDC1 other 9.41896630364448e-12 1 0.000100503080431626 5.82936560783968 1.510984942139 0.133157231491483 16.1875044116601 36.4735948199692 0.443814339978288 0.657395985655405 -38.2554969294846 46.3046490240894 -0.826169677035726 0.409157642434297 CCDC28A other 1 1 1 0.443814339978288 -0.826169677035726 8.6408164921158e-11 -132.592326312167 225.395289653874 -0.588265737566125 0.556657139993028 -1690.74440656888 318.518733685235 -5.30814745810115 1.76366323316409e-07 RRAGD other 6.37087399963698e-07 0.0015895896720508 1 -0.588265737566125 -5.30814745810115 6.91711263743579e-21 88.6362148199321 41.9103797861261 2.11489886925993 0.0350053445875375 -248.827936803531 54.3277672915888 -4.58012447793074 6.07278533057051e-06 HSF2 other 5.96393451599714e-17 0.051934460147039 1 2.11489886925993 -4.58012447793074 0.0368346447427172 -32.6390586797065 66.3971757725995 -0.491572996892073 0.623269178584 -276.029034229828 115.440640565792 -2.39109063218091 0.017222564666228 HSD17B6 other 1 1 1 -0.491572996892073 -2.39109063218091 6.43331328159609e-16 136.326153789848 27.4644539947539 4.96373071228315 9.93712137284115e-07 -116.966697340284 36.1938975532551 -3.231669017358 0.00132400175382385 NR1H3 other 5.24701031246977e-12 1 0.00891260415930123 4.96373071228315 -3.231669017358 0.0118406751740459 124.485466725409 134.919837574866 0.922662441365107 0.356693438912591 543.432650632805 198.160129208637 2.74239148310526 0.00635052214140881 TYMP other 1 1 1 0.922662441365107 2.74239148310526 1.03680803942244e-14 439.382982569111 95.216971889028 4.61454480070208 5.18791240459438e-06 -296.842293542397 139.84754052135 -2.12261361505374 0.0343492379455501 NCAPH2 essential 8.29239069930067e-11 1 0.0455394950875294 4.61454480070208 -2.12261361505374 3.75405706109932e-22 -66.8046049306367 144.612386096757 -0.461956314626738 0.644342536126991 -1375.55078620766 191.55583474475 -7.18093911386513 3.00057368342483e-12 SEC63 essential 3.27015910592362e-18 2.87574981819436e-08 1 -0.461956314626738 -7.18093911386513 7.51221702237273e-63 176.97059917126 78.2266661329325 2.26227970485831 0.0241704545470445 -882.674651778517 100.492345530599 -8.78350134150022 3.63058837859302e-17 KPNA6 other 7.29286028531945e-59 3.54744790472324e-13 1 2.26227970485831 -8.78350134150022 2.1950146053473e-16 16319.7469323493 3621.92014667455 4.50582737096873 8.49347415022202e-06 64523.3252119719 7303.64677687973 8.83439837427866 2.45305019084744e-17 VIM other 1.80144848660853e-12 2.39785656155338e-13 0.073986653322584 4.50582737096873 8.83439837427866 4.98368836389913e-08 -57.418138207327 36.8266488396828 -1.55914643380355 0.119685601918048 86.5303994222739 44.5361653307511 1.94292433530479 0.0526671667985008 FAS ts 0.000326880119788144 1 1 -1.55914643380355 1.94292433530479 0.234234663832921 353.289109355368 343.246633967009 1.02925731644414 0.303926806472739 725.080803593336 440.018600773137 1.64784125561812 0.100102377383183 RNASET2 other 1 1 1 1.02925731644414 1.64784125561812 0.566295725799448 1259.12083572938 1385.28134032114 0.908927882792015 0.363889193078498 1761.93303259477 1736.6613562093 1.01455187351012 0.310880872292332 CD44 other 1 1 1 0.908927882792015 1.01455187351012 7.6828306314184e-09 64.8069931754518 137.756881243245 0.470444689155081 0.638271514331153 -645.397069308156 180.954114958198 -3.56663383674501 0.000401461607278539 AGPAT4 other 5.27656807765816e-05 1 1 0.470444689155081 -3.56663383674501 0.0450685888663828 197.315689399055 110.113491637724 1.79193018461561 0.0738390366077002 -189.178436191761 228.899389822255 -0.82646981426496 0.408990716309059 BTN3A1 other 1 1 1 1.79193018461561 -0.82646981426496 2.12048465275128e-05 14.9705144046305 22.0576412354549 0.678699696165483 0.497688241501873 -68.0794823437597 27.1325933860644 -2.50914025707274 0.012464237736567 MIPEP essential 0.113933640392326 1 1 0.678699696165483 -2.50914025707274 0.430131021321871 -58.1021565686487 44.9434641794657 -1.29278322509005 0.196772255629464 -52.1840897919053 51.5262153621482 -1.01276776151971 0.31173408681224 PRKCH other 1 1 1 -1.29278322509005 -1.01276776151971 0.67340217970178 -203.595501363594 263.096170069483 -0.773844413279848 0.439441228814806 -295.441610133231 335.084067357783 -0.881693995369155 0.37842699966208 IFNGR1 other 1 1 1 -0.773844413279848 -0.881693995369155 0.00647200696358085 7.16680758545727 35.8737724306638 0.199778476024766 0.841746551997135 -186.897218435629 68.7974284583029 -2.71663087740125 0.00685620252777859 B4GALT7 other 1 1 1 0.199778476024766 -2.71663087740125 3.77044680596978e-07 103.962532299743 57.0138293008087 1.82346166841784 0.0689148899983419 -305.226159714534 94.5447907905307 -3.22837627713175 0.00133853567216097 VEZT essential 0.00234823427075798 1 1 1.82346166841784 -3.22837627713175 1.66552761429074e-08 -75.0180838183993 40.790324407507 -1.83911466525608 0.0665797034732839 -244.808998333734 53.0168698762508 -4.61756793460562 5.11955482559663e-06 POU2F2 other 0.000112589666726054 0.0439564977325726 1 -1.83911466525608 -4.61756793460562 2.20506250741797e-15 141.54581023663 57.1964406707355 2.47473109474542 0.0137130214435937 -430.433762484992 87.8975212505438 -4.89699545972496 1.3733229695007e-06 BRD9 other 1.78345455599966e-11 0.0120591489951857 1 2.47473109474542 -4.89699545972496 0.303545577991496 380.788572308771 497.198984502822 0.765867558417367 0.44416857360766 -545.634899199022 848.775503183023 -0.642849489827189 0.520658909547306 SNX1 other 1 1 1 0.765867558417367 -0.642849489827189 1.51790700039983e-10 20.7135489726897 53.6871447061788 0.385819530653971 0.699817653147706 -266.981626646862 68.5919876555282 -3.89231506145666 0.000114750864174606 TBPL1 other 1.1108043428926e-06 0.907335083028608 1 0.385819530653971 -3.89231506145666 7.57439425582641e-07 32.1334221895437 192.709509056132 0.166745389715999 0.867647515167301 -776.536262524122 246.233446759462 -3.1536587443488 0.00172356741458866 BCLAF1 essential 0.00463174208743785 1 1 0.166745389715999 -3.1536587443488 1.8441822200725e-30 -102.573329516701 163.250110069231 -0.628320124704367 0.530122486299556 -1332.43337601249 185.981442579428 -7.16433509458041 3.34458719671677e-12 SLC39A9 other 1.67175118249572e-26 3.203780075735e-08 1 -0.628320124704367 -7.16433509458041 0.724972874852236 -22.9234331028657 74.4527369562944 -0.307892416585334 0.758310555578534 -81.5903095582746 108.239508819242 -0.753794159344614 0.451377853332271 IBSP other 1 1 1 -0.307892416585334 -0.753794159344614 3.26059970888775e-07 4.23317180914625 9.93191213490097 0.426219216566646 0.670157977699771 -38.1571232166599 12.6494639352744 -3.01650120605148 0.00270636254036256 TFB1M other 0.00203885299796751 1 1 0.426219216566646 -3.01650120605148 0.733361863926016 49.022813497713 112.312080146513 0.43648745027037 0.662698181651346 -55.7557694566914 81.8489523665328 -0.681203214514073 0.496102900582583 RABEP1 other 1 1 1 0.43648745027037 -0.681203214514073 0.0143042384247667 186.560783738363 79.805504159684 2.33769319175117 0.0198557166819243 -27.178520553792 104.722913974767 -0.259527924904195 0.795350718550313 NUP160 essential 1 1 1 2.33769319175117 -0.259527924904195 1.45792952785976e-06 68.1938843467055 16.6026406553382 4.10741193297942 4.77740999790504e-05 179.799969535092 38.9800386648465 4.61261650048699 5.23083170636154e-06 BAK1 other 0.00871696064707351 0.0448857668722884 0.403165629723207 4.10741193297942 4.61261650048699 0.0117480771239267 627.911222984756 345.910767091915 1.81524046870131 0.0701707231919739 2141.22743396271 782.616216582551 2.73598653924245 0.00647211768849778 GRN other 1 1 1 1.81524046870131 2.73598653924245 0.00108912130280029 101.652925742813 394.621075363752 0.2575962919596 0.796839470230401 -2507.51200159508 783.7976866675 -3.19918270268997 0.00147827302870996 ARHGAP31 other 1 1 1 0.2575962919596 -3.19918270268997 8.11324023181251e-07 38.3986298875689 14.0938047590272 2.72450417357842 0.00669755513777287 -102.778028130548 32.0825837167682 -3.20354585646511 0.0014565646720061 CENPQ other 0.0049458312453129 1 1 2.72450417357842 -3.20354585646511 7.63769705819499e-36 743.775229357804 155.788506377883 4.77426253483483 2.46307557580391e-06 -715.074991505268 207.196033103573 -3.45120020298755 0.000612257950665316 SARS essential 7.05570454236053e-32 1 0.0218474803573807 4.77426253483483 -3.45120020298755 2.56098413298814e-14 23.033560809802 86.7637679398893 0.265474418143757 0.790769202610952 -469.534467503571 102.496762637803 -4.58096875862105 6.04584876110178e-06 ARID4A other 2.03828727144526e-10 0.0517161903024646 1 0.265474418143757 -4.58096875862105 1.61296967990592e-08 58.5401236540234 39.8643195898722 1.46848420483003 0.142702180335391 -131.80195545899 49.150826014559 -2.6815816975273 0.00760887224286207 IFT88 other 0.000109117398845636 1 1 1.46848420483003 -2.6815816975273 0.00101801737867474 87.1036416184976 25.8822477330122 3.36538165143203 0.000831705731853108 -5.39333526011512 51.5910221067212 -0.104540190131501 0.916788529119227 ZCCHC8 other 1 1 1 3.36538165143203 -0.104540190131501 0.0224115397691936 22.1503336497589 42.2468169046105 0.524307753168063 0.600329731871585 103.043213916609 54.2522035593487 1.89933693299454 0.0581768967266279 LRRC7 other 1 1 1 0.524307753168063 1.89933693299454 2.24363024896133e-05 -214.935163212575 113.354413586943 -1.89613404905243 0.0586001683880603 -495.108643900532 128.893160284488 -3.84123286920538 0.00014049674301494 FUT8 other 0.120236145041838 1 1 -1.89613404905243 -3.84123286920538 1.57512168587608e-06 91.991687932019 71.9426205284621 1.27868136101082 0.201689483443215 -266.198201322994 98.7077290291809 -2.69683239540743 0.00727146813311954 UBA6 other 0.0093971759779367 1 1 1.27868136101082 -2.69683239540743 1.5719409146352e-05 22.8229848809437 75.6879427430786 0.301540563183438 0.76314576076424 -488.898738570184 131.313787713055 -3.72313332122074 0.00022249905682761 PIAS1 other 0.0857336574842037 1 1 0.301540563183438 -3.72313332122074 0.399504474167664 72.3687580025612 64.3002880221598 1.12548108614414 0.261001558243199 -14.1426742271807 120.710936079442 -0.117161499086323 0.906785779889684 SLC4A7 other 1 1 1 1.12548108614414 -0.117161499086323 7.74093297974972e-10 815.706303389754 319.833954613077 2.55040558272358 0.0110998525250194 -1852.15050615545 525.570677611718 -3.52407503891185 0.000469783592328386 APBA2 other 5.53399298722307e-06 1 1 2.55040558272358 -3.52407503891185 0.562624084763457 -16.7758610873892 39.3774408232106 -0.426027205848807 0.670297298347491 -29.8862890217289 30.76002530952 -0.97159507253329 0.331788272544795 MAP2K3 other 1 1 1 -0.426027205848807 -0.97159507253329 0.0241344853327388 11.8480090097339 12.6865210394545 0.933905282061734 0.350869664286423 -52.5483388303432 26.7478069635861 -1.96458494342663 0.050096972824304 ASTE1 other 1 1 1 0.933905282061734 -1.96458494342663 3.8278987430854e-19 8.67379967711373 20.8242181383682 0.41652462625391 0.677230655372663 -144.91038326293 26.4397094429151 -5.48078576944274 7.16886162926186e-08 PEX3 other 3.24605813413642e-15 0.000652724851344292 1 0.41652462625391 -5.48078576944274 0.000123667070660145 303.650044437779 239.587101635629 1.26738894692077 0.205689650955782 -1870.5428833517 552.96001454866 -3.38278145641052 0.0007820232386944 GABARAPL2 other 0.605473977952072 1 1 1.26738894692077 -3.38278145641052 0.909022730217754 96.6686609351084 316.997007313942 0.304951336147383 0.760548069132136 165.591803085621 384.294231708805 0.430898487206794 0.666754157490007 VCL other 1 1 1 0.304951336147383 0.430898487206794 0.00345255298423778 43.8954198965487 22.2379443390977 1.97389737231125 0.0490228216152098 -41.107667894141 37.9627130876945 -1.08284325725565 0.279475116099655 DAPK2 other 1 1 1 1.97389737231125 -1.08284325725565 0.000606676993686321 106.322485294698 43.6084998855453 2.43811379831344 0.0151634726627297 -199.769334017608 91.3791927799327 -2.18615778866322 0.0293363465503158 ADSS other 1 1 1 2.43811379831344 -2.18615778866322 0.00121085749583674 3742.71166504538 1018.62754582497 3.67426904994427 0.000268074470851099 2567.66132610755 2862.67178047431 0.896945763611827 0.370240584556316 TIMP2 other 1 1 1 3.67426904994427 0.896945763611827 2.69106782986582e-09 234.16210031149 88.9762516117705 2.63173707668883 0.00879553603581767 -486.615406175413 144.335557601452 -3.37141737117257 0.000814303767655964 RFC1 other 1.88509301482101e-05 1 1 2.63173707668883 -3.37141737117257 8.61269911423629e-05 56.0082939392397 44.4084945830827 1.26120676832346 0.207908761072589 -267.408783612059 85.9880076038111 -3.1098381165446 0.00199465167631142 TBC1D23 other 0.429859812791533 1 1 1.26120676832346 -3.1098381165446 1.1297208222236e-08 288.057732926546 71.3239002561688 4.03872659644173 6.34525716925726e-05 -411.900855539673 170.866701631789 -2.41065609393749 0.0163348135634206 CUL3 essential 7.69565824098718e-05 1 0.532430529072377 4.03872659644173 -2.41065609393749 0.000946212485506571 -181.259650271437 145.19336822276 -1.24840171758633 0.212550872848221 -538.034863736806 171.875821901581 -3.13036969239859 0.00186267497800982 CYP46A1 other 1 1 1 -1.24840171758633 -3.13036969239859 2.41444404633179e-74 191.553234814682 41.7675800162954 4.586170296195 5.90048984536956e-06 -429.124680431439 53.6367806914738 -8.00056742592034 1.11860127840359e-14 ZZZ3 other 2.36325783254955e-70 1.08448393941228e-10 0.0516587885962105 4.586170296195 -8.00056742592034 0.00234965527732982 -38.5957646428112 94.5676604275509 -0.408128576601298 0.683379172129829 -718.294967162579 207.129366124767 -3.46785673418178 0.0005766152397089 TUBG2 other 1 1 1 -0.408128576601298 -3.46785673418178 0.204925517275602 23.1557824504642 15.6153212916634 1.48288863341073 0.138824795923225 -4.17216740800763 29.2649357428376 -0.14256540471061 0.886699128332992 RPL26L1 other 1 1 1 1.48288863341073 -0.14256540471061 0.964754548019271 -12.2855497636079 46.6859714538607 -0.263152921124275 0.792557313097729 -6.54596516749502 94.4524729866931 -0.0693043279916795 0.944779227421216 FLT4 other 1 1 1 -0.263152921124275 -0.0693043279916795 6.59885364546063e-12 107.33904830687 60.0596513683315 1.78720731574988 0.074598511463671 -438.692047523627 97.3672827308115 -4.50553856716394 8.51400971951246e-06 NSUN2 other 4.99203278279097e-08 0.0723520545964169 1 1.78720731574988 -4.50553856716394 2.25801795365438e-93 89.5802012799071 35.6252652162251 2.51451324604059 0.0122769941319949 -550.700631987043 45.5209555081382 -12.0977388510351 2.87909650984758e-29 FBXO42 other 2.22256707178201e-89 2.83533424289789e-25 1 2.51451324604059 -12.0977388510351 0.087422900586787 10.2453166953795 36.7867991392679 0.278505250119552 0.780755969487642 -117.245557262808 66.8652421836022 -1.75346044423004 0.0802224729736618 MFAP3 other 1 1 1 0.278505250119552 -1.75346044423004 0.0180694482954572 38.6714626659004 23.1818028744902 1.66818184397795 0.0960302967928382 -39.2068246203754 38.9250180930812 -1.00723972758652 0.314403685001962 METTL1 essential 1 1 1 1.66818184397795 -1.00723972758652 5.95519811723703e-09 116.987690672286 38.0753186034385 3.07253346690896 0.00225552485775512 -71.2818743542346 50.5449661138491 -1.410266537595 0.159173993894653 AGA other 4.10908670089355e-05 1 1 3.07253346690896 -1.410266537595 0.00237400484838933 25.4588713957192 16.0924471946836 1.58203852327257 0.114365877929374 -45.1128231865706 26.1990272349729 -1.72192741287546 0.0857919077965871 PI4K2B other 1 1 1 1.58203852327257 -1.72192741287546 2.21378756966113e-05 -236.145620434708 123.17261759353 -1.91719251444334 0.0558666648591779 -913.150710709172 197.999431374498 -4.61188552093379 5.25160355421212e-06 BOD1L1 other 0.11870328948523 0.04505875849514 1 -1.91719251444334 -4.61188552093379 0.00493751883846829 149.731468990274 114.912970661843 1.30299885320076 0.193264455170772 -387.797192796223 204.922512578333 -1.89240893017054 0.0591002285130735 MAT2B other 1 1 1 1.30299885320076 -1.89240893017054 0.479646679044145 37.0083789445238 30.6422588630455 1.20775622678248 0.227792780065192 39.0591214795265 41.1284985478214 0.949685081115015 0.342796000281642 TLL1 other 1 1 1 1.20775622678248 0.949685081115015 6.53738098450856e-10 471.742881923995 80.2060417256257 5.88163773918385 8.07186919534366e-09 -157.88794183469 185.113195563183 -0.852926455914373 0.394166255345178 EDC4 essential 4.68860964208954e-06 1 7.52378927697983e-05 5.88163773918385 -0.852926455914373 0.0500405554455574 -254.079012807537 573.510990831088 -0.44302379007479 0.657968254126016 -2084.37295893666 951.494031997508 -2.19063166855692 0.0290072234008014 TRIO other 1 1 1 -0.44302379007479 -2.19063166855692 0.238189644659478 -26.5438783894818 111.882103682788 -0.237248652963657 0.81257482150613 423.259490550532 294.684696503167 1.43631310201405 0.151627108016379 MSR1 other 1 1 1 -0.237248652963657 1.43631310201405 0.253105139121679 72.2996436391721 44.9985141394093 1.60671179975369 0.108839885380708 18.3058620640288 103.857000533312 0.176260261417402 0.860171131960303 CDH1 ts 1 1 1 1.60671179975369 0.176260261417402 0.729351369504345 15.6597476382374 43.4253937460152 0.360612680447471 0.718563652134416 -24.0388584263725 71.1931618461993 -0.337656845165893 0.735784303510713 DNAH5 other 1 1 1 0.360612680447471 -0.337656845165893 0.00938152632793791 34.0143700007494 86.9748786941755 0.391082695502826 0.69592627624616 -544.513925622924 200.73547306917 -2.71259442737006 0.00693884401856726 RIPOR1 other 1 1 1 0.391082695502826 -2.71259442737006 0.965651064920234 -5.39892581006917 20.9143067436624 -0.258145100205399 0.796417576796712 -7.88016191544212 44.4926837344359 -0.177111409203287 0.859503696003337 C6 other 1 1 1 -0.258145100205399 -0.177111409203287 0.00224767439508993 25.4705171023841 44.4594046632207 0.572893795931882 0.567012608140864 -250.865488709149 92.6796825544835 -2.70680133762514 0.0070608669357439 RAI14 other 1 1 1 0.572893795931882 -2.70680133762514 5.75105497541288e-39 707.39387174906 112.438278090049 6.29139723380081 7.63508656658433e-10 -75.4117694909015 137.322371051776 -0.549158661573564 0.583176421082318 PNKP essential 5.35365707661185e-35 1 7.20828522751226e-06 6.29139723380081 -0.549158661573564 0.0116557049483118 -25.5972210309645 49.9940712352916 -0.512005131778405 0.608906062311439 -352.885909441785 119.318599777536 -2.95750964308771 0.00326955498404128 PHLPP2 other 1 1 1 -0.512005131778405 -2.95750964308771 0.000217232676791969 85.8124561376141 21.8863006730049 3.92082962852911 0.00010245982678832 32.5619609800228 39.7847769916147 0.818452771191499 0.413545790112734 SPDL1 essential 1 1 0.850826401650206 3.92082962852911 0.818452771191499 2.22120837883422e-61 115.900266342463 20.7943418700427 5.5736443628175 4.36692137022286e-08 -142.891078037411 26.5713821021523 -5.37763062109729 1.23052286748442e-07 PQLC2 other 2.15323940244189e-57 0.00111460761336739 0.000402018781342716 5.5736443628175 -5.37763062109729 0.0787659090149371 6.4830967617104 30.18274635664 0.214794793194297 0.830027282930141 -49.7041311348529 21.9960859563197 -2.25968071017528 0.0243316408875684 CTNS other 1 1 1 0.214794793194297 -2.25968071017528 0.00418084391422381 -88.6676436379 52.6246258968411 -1.68490781885487 0.0927203049073182 -292.542123210719 88.140654255334 -3.31903734641288 0.000978910241534218 RTN4R other 1 1 1 -1.68490781885487 -3.31903734641288 0.014269466035685 78.9840854514978 41.6487666929168 1.89643275715366 0.0585605849242302 67.3699198042678 31.1325106271165 2.16397323721102 0.0310062748761554 PHF23 other 1 1 1 1.89643275715366 2.16397323721102 0.000198162543747125 -281.851404899136 99.0394848671457 -2.84584885792994 0.00464114294886292 -782.233909702209 190.388917531818 -4.1086105212583 4.76702424464806e-05 CDH10 other 0.943451870780063 0.388655486666156 1 -2.84584885792994 -4.1086105212583 5.06433250673101e-05 190.056832804324 68.1191772852319 2.79006353832649 0.00549980264678428 -84.9504589517046 105.947624073902 -0.801815611197177 0.423094416143102 RAB27B other 0.260256047520907 1 1 2.79006353832649 -0.801815611197177 2.93595200374798e-09 261.288882339417 94.7613581322952 2.75733576944554 0.00607165127580512 -583.896522226687 173.66175716798 -3.36226312429795 0.000841074162258116 PSMA4 other 2.05340483142134e-05 1 1 2.75733576944554 -3.36226312429795 0.0081045052565104 93.3441706011661 142.668650100799 0.654272473561752 0.513281235918855 -391.519873477604 201.509668921251 -1.94293343626409 0.0526675367752845 MYO16 other 1 1 1 0.654272473561752 -1.94293343626409 5.24995520055388e-09 190.137973092051 52.4604474372798 3.62440624089937 0.000323625188225308 -252.244358357154 97.5675096503608 -2.58533152338404 0.0100506649954189 LSG1 essential 3.62824403910279e-05 1 1 3.62440624089937 -2.58533152338404 1.76915468836128e-05 -8.86537383302259 71.7526245180348 -0.123554697721117 0.901724800119925 -423.171844824365 109.646381762396 -3.85942370393379 0.000130841211801124 PARP3 other 0.0958881841091814 1 1 -0.123554697721117 -3.85942370393379 0.81198697333961 1026.56193433194 1687.51639971476 0.608327086187407 0.54328588207724 1532.09786882218 3516.01566554652 0.435748305627653 0.663234021672349 TNC other 1 1 1 0.608327086187407 0.435748305627653 6.71479419961284e-51 330.178104821063 52.696307337335 6.26567821360671 8.88595838738059e-10 -214.867112430355 67.3703820775994 -3.18934086172859 0.00152834285551913 THAP3 other 6.42001473424984e-47 1 8.38123595097737e-06 6.26567821360671 -3.18934086172859 7.12800342200819e-06 11.2507450323338 26.5900482316591 0.423118639511839 0.672417325481337 -73.4241686041585 30.875129382484 -2.37810075852875 0.0178321292713569 TDP1 other 0.0401876832932822 1 1 0.423118639511839 -2.37810075852875 0.0729626424517655 43.8109742471446 23.2685732361847 1.88283887466786 0.0603877389248012 64.8310968997889 28.2596648861045 2.29412122051266 0.0222581675315269 AIFM2 other 1 1 1 1.88283887466786 2.29412122051266 4.47343216294228e-14 34.9861852247142 26.7506827472464 1.30786139386725 0.191607899534451 -103.542943273448 31.0204795520568 -3.33788983177029 0.000916397032320759 SPATA7 other 3.54340561626658e-10 1 1 1.30786139386725 -3.33788983177029 2.92940122069389e-25 522.4508291881 98.6800700901888 5.29439053610932 1.89499831748558e-07 11.2830891387795 119.791868157313 0.0941891074272445 0.925002107456505 AP2S1 essential 2.59662124202307e-21 1 0.00172596446756586 5.29439053610932 0.0941891074272445 0.541002169040529 54.1355343960399 49.0297249012163 1.10413702106448 0.270139908703601 53.8925610125242 65.3808363619876 0.824286809580449 0.410225250283566 ZIC2 other 1 1 1 1.10413702106448 0.824286809580449 0.415901695241428 -105.447096273055 80.200439392032 -1.31479449579588 0.189270117723957 -119.092313081622 147.176269550658 -0.809181489959089 0.418852111349771 LCP2 other 1 1 1 -1.31479449579588 -0.809181489959089 2.33984827721702e-48 54.7691456004377 26.712319853186 2.05033280154832 0.0409266554636159 -248.52764739634 34.3032285128048 -7.24502206267753 1.96385689123682e-12 TRIT1 other 2.22613165094427e-44 1.8849098442091e-08 1 2.05033280154832 -7.24502206267753 0.813192760248495 -8.45175330642282 22.584144598311 -0.374233935212003 0.708411794652564 -15.1456042904185 25.8322786152729 -0.586305393960251 0.557973018898217 ADRB1 other 1 1 1 -0.374233935212003 -0.586305393960251 1.52869210588038e-05 -54.2955532191211 45.7598533955591 -1.1865324993456 0.236056732632552 442.298923866664 113.919287010209 3.88256401066683 0.00011933037773455 CUL7 other 0.0834665889810687 0.942351992969738 1 -1.1865324993456 3.88256401066683 1.89598190564961e-11 113.478190272345 18.9651709625273 5.98350473594796 4.55196698594553e-09 27.6921544025393 21.3752915892248 1.29552171426278 0.195824224495164 CNTLN other 1.42028004552212e-07 1 4.25927550874924e-05 5.98350473594796 1.29552171426278 0.929650213019067 18.6718707269211 49.0348268568758 0.380787940404502 0.703548657704211 16.7044001017145 83.4274924611059 0.200226563317867 0.841398053738732 EPHA3 other 1 1 1 0.380787940404502 0.200226563317867 0.509481245977433 550.461266584199 663.811797747475 0.829242969847915 0.40741965055736 -664.06909259904 1457.48007628743 -0.455628247276349 0.648883637174521 HSPA5 essential 1 1 1 0.829242969847915 -0.455628247276349 0.332498456970236 24.4901779095629 16.6426083229403 1.47153483602721 0.141864628198716 32.887509266123 39.3254007264389 0.836291777289187 0.403446782806928 DSG2 other 1 1 1 1.47153483602721 0.836291777289187 1.76959328521432e-37 200.618078052875 30.6597324490615 6.54337340960769 1.71742486479225e-10 -494.078182496385 65.6708315399035 -7.52355605846363 3.15800629151861e-13 WDR37 other 1.64200560935037e-33 3.04242326124903e-09 1.6310383940932e-06 6.54337340960769 -7.52355605846363 1.33125869163325e-15 896.293189188635 122.713536142208 7.30394720391687 1.37610393287364e-12 13.4685893330542 219.580376471541 0.0613378551830649 0.951118775439738 POLR2B essential 1.0809820576062e-11 1 1.32436242499759e-08 7.30394720391687 0.0613378551830649 0.0150229192446391 14.7709616245158 129.332994624516 0.114208765268285 0.909124756430489 -434.952696511899 199.079544694676 -2.18481862201853 0.029432673719016 FAM214A other 1 1 1 0.114208765268285 -2.18481862201853 0.000211988668077907 -159.603288214046 209.346854462182 -0.762386846576088 0.446241394081362 -1292.46918457969 339.6187687103 -3.80564710686583 0.000161657715838425 ARAP2 other 1 1 1 -0.762386846576088 -3.80564710686583 0.997480827728803 26.8216092507837 378.375835789495 0.070886157925015 0.943520788077791 26.4005059021945 789.767754421618 0.0334281891788919 0.973348393128657 CP other 1 1 1 0.070886157925015 0.0334281891788919 0.00178222061557287 118.841123175378 33.1880408779752 3.58084177406946 0.000381111462489772 115.776083986481 62.1654126864926 1.86238744316479 0.063222464605669 DTNBP1 other 1 1 1 3.58084177406946 1.86238744316479 0.994081243822344 -8.34937201485921 112.682578581395 -0.0740963875691584 0.940967671820925 4.66130388770417 183.450901497209 0.0254089996269388 0.979740357852046 FAM184B other 1 1 1 -0.0740963875691584 0.0254089996269388 3.2513230411798e-07 747.833211446374 1457.41934116634 0.513121508904842 0.608125621481975 -9153.64287904885 2268.60640154253 -4.03491891445994 6.44765184394053e-05 MAP4 other 0.00203337742995385 0.520196550769122 1 0.513121508904842 -4.03491891445994 1.8061646689611e-20 21.6209017826014 94.8329312352566 0.227989386186591 0.81976112785385 -751.635002746283 122.91949527374 -6.1148559150231 2.14556256407628e-09 GOPC other 1.54914743656794e-16 1.99966430971909e-05 1 0.227989386186591 -6.1148559150231 0.0162757135108959 105.199283865922 53.0481352569762 1.98309108051235 0.0479814119336228 -109.697017110985 107.315513490901 -1.02219160625166 0.3072544599431 TSPAN17 other 1 1 1 1.98309108051235 -1.02219160625166 0.00111690409813211 66.7351424543709 45.6713569033577 1.46120341017205 0.144676627940914 -213.89590443686 89.8363702723507 -2.38094998482693 0.0176946412351802 NOP16 essential 1 1 1 1.46120341017205 -2.38094998482693 0.00390518584576647 33.672263495163 64.9425562628881 0.518493041124796 0.604377345647045 -254.4577774348 104.394868464122 -2.43745484024678 0.0151898335943431 CC2D2A other 1 1 1 0.518493041124796 -2.43745484024678 5.09421263030758e-15 195.296078431373 26.4263529262684 7.39020170419524 7.49221774086711e-13 -55.8501256913021 61.5954549192437 -0.906724786179855 0.365050900804852 MRPS10 essential 4.09676579729336e-11 1 7.21725334977729e-09 7.39020170419524 -0.906724786179855 7.10193512324525e-19 -1135.24169294059 485.295827129016 -2.33927767245934 0.0197696658041177 -4283.83261214415 620.063304945784 -6.90870202764008 1.73155154087934e-11 VPS13D essential 6.00823711426548e-15 1.64930284268757e-07 1 -2.33927767245934 -6.90870202764008 2.33323340466226e-16 587.591952942944 153.832561653257 3.81968516046292 0.000152964453851301 -1402.51213738529 315.335598536411 -4.44768095925377 1.10244301803661e-05 CELF2 other 1.91441800852538e-12 0.0931784838844545 1 3.81968516046292 -4.44768095925377 0.0607631898073248 322.124626687382 167.669489557418 1.92118809174922 0.0553581964227554 -184.932164615931 346.839195779967 -0.53319280769308 0.594171173164284 FAM120A other 1 1 1 1.92118809174922 -0.53319280769308 2.05806702741304e-10 -163.764962476469 180.018577089078 -0.90971145936474 0.363475019018677 -1019.03994672834 231.174919302266 -4.40809041830322 1.31338830406372e-05 COL9A2 other 1.49950763617314e-06 0.110522771001827 1 -0.90971145936474 -4.40809041830322 0.000214293561457359 136.069183191991 112.61044044931 1.20831765375468 0.227580046381683 -453.336972316657 181.599563709958 -2.49635496393981 0.0129159294858709 KITLG other 1 1 1 1.20831765375468 -2.49635496393981 4.06647645733419e-43 188.333579378247 109.676589276574 1.71717210227355 0.0866562438507952 -943.786991050875 140.246200061815 -6.72950133860946 5.35965567308375e-11 H6PD other 3.82777428928868e-39 5.08256147478532e-07 1 1.71717210227355 -6.72950133860946 1.51809478845802e-38 67.3009113233273 144.500043574314 0.465750110924467 0.641626949938372 -1344.90009713507 184.895057562282 -7.27385639652392 1.63426906774497e-12 VAMP3 other 1.41182815326596e-34 1.5693885857555e-08 1 0.465750110924467 -7.27385639652392 7.82376470535384e-20 -189.134963165077 137.919844929364 -1.37133973187066 0.17097443111026 -1111.15160272852 176.475363165417 -6.29635538240537 7.44320204622305e-10 PER3 other 6.66662990543201e-16 6.98321215976647e-06 1 -1.37133973187066 -6.29635538240537 1.17793789267993e-19 -26.9503192360166 21.3817838384915 -1.2604336214222 0.208187115811468 -169.158109686221 27.3590654771602 -6.18289063372568 1.44848351079555e-09 UTS2 other 1.00277852803842e-15 1.35346299248736e-05 1 -1.2604336214222 -6.18289063372568 1.28599497713068e-16 -41.5377763753975 153.999565625462 -0.269726581414005 0.787497927942734 -1101.27593815501 196.136647703702 -5.61484022006269 3.50349418621612e-08 ARID1B other 1.05927406266254e-12 0.000321060207224845 1 -0.269726581414005 -5.61484022006269 1.20159872399585e-11 256.909761543349 84.2158679099834 3.05060991377486 0.00242376971085479 -435.502772304553 129.497549722567 -3.36301940258766 0.000839313270200676 CLPTM1L other 9.04563519424075e-08 1 1 3.05060991377486 -3.36301940258766 0.0137975017195733 182.479180189215 125.860228700452 1.44985578107853 0.147814392062634 -203.806052201965 201.066946159398 -1.01362285594369 0.311322343006094 NEDD4L other 1 1 1 1.44985578107853 -1.01362285594369 9.90922704330239e-29 -32.4334885033155 56.1229914902211 -0.57790020884697 0.563628468292862 -471.25306813373 64.7185881376985 -7.28157213706622 1.54289028218221e-12 JKAMP other 8.92424987519813e-25 1.48225469409245e-08 1 -0.57790020884697 -7.28157213706622 0.384134125961191 -1119.96565167813 952.20106558643 -1.17618609362549 0.24015938718883 -1563.56072980555 1157.74484929009 -1.3505227259394 0.177545717163142 DKK3 other 1 1 1 -1.17618609362549 -1.3505227259394 1.08894609904894e-07 99.5641968587238 70.4079684780202 1.41410409945013 0.15804663488381 -555.934544782172 131.883060917838 -4.21535973545925 3.03466985360641e-05 MCUR1 other 0.000699212290199324 0.250694076606425 1 1.41410409945013 -4.21535973545925 0.00012047278534924 239.114204545456 382.737978684434 0.624746478955005 0.532463513279412 -1765.59705255681 584.83011103512 -3.01899136046842 0.00268467309898444 LIMA1 other 0.591400903279418 1 1 0.624746478955005 -3.01899136046842 2.25105658146744e-05 -71.594145716302 99.2471102230757 -0.721372597704671 0.471066946772584 -625.968516717464 153.245936818583 -4.08473157404821 5.25177714682139e-05 LETMD1 other 0.120589101069211 0.427021999808047 1 -0.721372597704671 -4.08473157404821 3.8658267630785e-05 -116.573587390867 145.274331872757 -0.802437608131433 0.422737034522661 -903.7024702675 221.996128501109 -4.07080283953233 5.56360402373068e-05 SLC4A8 other 0.201796157032698 0.450818834042897 1 -0.802437608131433 -4.07080283953233 0.344052829464499 19.362705303623 67.148559083015 0.288356229352369 0.773210787964097 209.20436547405 145.704515640009 1.43581250419808 0.151771102619823 LAMC3 other 1 1 1 0.288356229352369 1.43581250419808 0.0081077100703151 38.4060289821814 14.0116022855733 2.74101620924004 0.00637612237856907 27.2304361447693 18.0018786243593 1.51264413636932 0.13109290499828 PTGER3 other 1 1 1 2.74101620924004 1.51264413636932 0.00457062458019177 148.182143290098 143.758915355808 1.03076837303163 0.303222212481211 -691.361963066233 290.845079290256 -2.37707980053626 0.0178819065584534 MAPK9 other 1 1 1 1.03076837303163 -2.37707980053626 0.208589347752507 84.8074042758786 63.8471635637771 1.32828773499334 0.184774759562906 -50.2689507014308 122.443790265836 -0.410547162843397 0.681605372179529 COL23A1 other 1 1 1 1.32828773499334 -0.410547162843397 0.0724285691039172 421.92586921372 222.812899635574 1.89363304325651 0.0589324661619004 -282.558688210954 514.245647545303 -0.549462478797279 0.582968137462243 BCAR1 other 1 1 1 1.89363304325651 -0.549462478797279 3.14061985619033e-25 142.637259501794 38.2811756778038 3.72604176795169 0.000219966613684049 -199.900313682385 45.473788398499 -4.39594590031964 1.38571726426686e-05 FAM160A2 other 2.78290325457025e-21 0.116414107371059 1 3.72604176795169 -4.39594590031964 0.450809579468777 156.739141350743 130.065375866427 1.20507967863568 0.228823225873447 7.2297891036912 299.748881127867 0.024119486539825 0.980768284221508 HERPUD1 other 1 1 1 1.20507967863568 0.024119486539825 0.000333083271303177 78.681568331407 19.6507613534558 4.00399592240583 7.31739609524424e-05 63.012470806106 30.5882059764336 2.06002505850305 0.0399877334575088 RAD51 essential 1 1 0.612612401093848 4.00399592240583 2.06002505850305 0.020980148468763 40.4151912181308 14.5645157950418 2.77490798780205 0.00575801024373979 28.8751264670176 28.1993451887011 1.02396443157791 0.306417267266286 POLQ other 1 1 1 2.77490798780205 1.02396443157791 0.0389969246570152 61.8145974598144 134.222148228226 0.460539473371469 0.64535760776373 708.528224279769 285.198124422822 2.48433689987854 0.0133519861567799 CYBA other 1 1 1 0.460539473371469 2.48433689987854 0.00108193291097757 104.001984715834 29.1834757847194 3.56372851140266 0.000405805834418446 37.4633105802046 57.4044152438457 0.652620716038407 0.51434319641741 THOC3 essential 1 1 1 3.56372851140266 0.652620716038407 0.0510726147203621 94.100800108181 49.1329353904803 1.91522853988515 0.0561157841136252 37.685284770896 62.5766001364493 0.602226466262511 0.547335740188213 HEBP2 other 1 1 1 1.91522853988515 0.602226466262511 4.53284871029651e-05 108.891315502029 33.4670572208601 3.25368659644675 0.00122780293392821 -108.053645008672 67.687617892296 -1.59635762600785 0.111133484482494 MPHOSPH9 other 0.234529592270741 1 1 3.25368659644675 -1.59635762600785 1.56704128241549e-35 157.754361367597 44.6095111054954 3.53633916754949 0.00044898215119671 -238.688901796623 57.0084140269359 -4.18690654477504 3.4198592964059e-05 SIKE1 other 1.44606569541301e-31 0.281499291365762 1 3.53633916754949 -4.18690654477504 9.37187555959851e-09 179.492461526614 54.0687454089028 3.31970827451563 0.000976442583775173 -37.6896561449484 68.3172646204901 -0.55168567351633 0.581445074295515 RRP12 essential 6.40661413254154e-05 1 1 3.31970827451563 -0.55168567351633 2.14145109103897e-05 93.4036137369865 106.974922116368 0.873135608693234 0.383068686315213 -375.158310398469 145.966513047724 -2.57016696888424 0.0104952498771074 FNIP2 other 0.114974509077883 1 1 0.873135608693234 -2.57016696888424 0.0138999811530714 181.040678424214 293.822253100972 0.616157137567111 0.538110891167788 -610.965772645977 394.37262650877 -1.5492093811242 0.122053613104725 MSMO1 other 1 1 1 0.616157137567111 -1.5492093811242 6.51845135174896e-06 135.797604232256 77.5568800406123 1.75094207194959 0.0806640016550728 -270.40730034856 100.992405229675 -2.67750134016121 0.00769928918845032 TTC17 other 0.0369074715536026 1 1 1.75094207194959 -2.67750134016121 0.858783993866059 -9.62952547690326 18.1526108339611 -0.530476060164729 0.596055107637532 -4.41049200456804 23.7798087551786 -0.185472139409344 0.852945981715613 ALX4 other 1 1 1 -0.530476060164729 -0.185472139409344 1.47011019058612e-09 -54.4858604102755 195.058917371111 -0.279330271820452 0.780123527923811 -872.728082791048 226.468808536664 -3.85363480485551 0.000133828120829959 FOXN3 other 1.03922089372532e-05 1 1 -0.279330271820452 -3.85363480485551 2.42729593374238e-41 166.751062687361 59.9218620522361 2.78280842711459 0.00562207150139042 -431.802216224678 76.5692274760682 -5.63937015506181 3.06469884129428e-08 AKR7A2 other 2.27413356032324e-37 0.000281032883746685 1 2.78280842711459 -5.63937015506181 6.81849091776796e-55 259.559943015929 52.284810546557 4.96434701211748 9.89148859271684e-07 -346.903377144386 66.810466416957 -5.19235077599069 3.18591870966544e-07 MRTO4 essential 6.56075196107633e-51 0.0028558575313441 0.008872665267667 4.96434701211748 -5.19235077599069 0.662786390936655 -3.85752292832132 21.4643079780178 -0.17971801989945 0.857459398119081 -29.8257817061178 36.3547611512985 -0.820409232837237 0.412441672159028 LAMA3 other 1 1 1 -0.17971801989945 -0.820409232837237 6.62813959068555e-17 -45.645737350399 79.5872228957427 -0.573530972555654 0.566581620642134 -589.3521336754 98.2532878243568 -5.99829427315408 4.1986214467202e-09 AP5M1 other 5.48345988337415e-13 3.89925973756905e-05 1 -0.573530972555654 -5.99829427315408 1.98867431475929e-08 118.853529099593 33.7223420003566 3.52447434102697 0.000469201815848556 -119.006663128722 54.9010691665521 -2.16765656726455 0.0307253142123998 ANAPC4 essential 0.000133798007897005 1 1 3.52447434102697 -2.16765656726455 2.64804267839694e-05 -35.6005900473649 36.1539263680554 -0.984694986789058 0.325318777917233 82.1276907411247 41.3181278576024 1.9876914807023 0.0474694728924295 KCNQ1 other 0.141061233478205 1 1 -0.984694986789058 1.9876914807023 1.26485498720705e-76 171.762730697095 48.5235861226802 3.53977816608266 0.00044333398836954 -576.028882339447 62.3090123559131 -9.24471213007089 1.03770728943687e-18 TRAPPC3 essential 1.23955788746291e-72 1.01643429000342e-14 1 3.53977816608266 -9.24471213007089 1.94076952484303e-75 281.240846979461 121.231051167646 2.31987468780208 0.0208065145539962 -1590.58166226243 155.672481543867 -10.2174876798262 3.9999911214034e-22 THRAP3 other 1.90098374958375e-71 3.93079127500312e-18 1 2.31987468780208 -10.2174876798262 6.81451372033128e-07 665.831633071962 128.091048935236 5.19811211327197 3.10020222953581e-07 181.876477893183 269.922910484848 0.67380896851804 0.500789821043457 PHPT1 other 0.00417797038826447 1 0.00281219344241193 5.19811211327197 0.67380896851804 0.381482502954849 -111.946181787818 81.2196807119394 -1.378313492574 0.168814998434865 -65.9365527535385 170.046973718638 -0.387754932132095 0.698387065939901 ENTPD2 other 1 1 1 -1.378313492574 -0.387754932132095 1.02990932924857e-07 274.101690784813 79.0993546037851 3.46528353053966 0.000581887674470986 -581.448849020766 171.838732372 -3.38368911941247 0.00077950898525221 ARID4B other 0.000663261608036082 1 1 3.46528353053966 -3.38368911941247 0.00304397371267073 79.8327839406257 23.8133687377305 3.35243555079784 0.000871052413827191 14.4253286486913 49.8995933897278 0.289087098085671 0.772652446323788 OPN3 other 1 1 1 3.35243555079784 0.289087098085671 1.75964760738393e-08 213.176577118944 44.1421843065701 4.8293164569841 1.90099390122815e-06 -200.792230863369 92.49749888357 -2.17078551622367 0.0304875309585712 SDCCAG8 other 0.000118723424070194 1 0.0169245487026342 4.8293164569841 -2.17078551622367 4.52184233174396e-33 -1096.87234695034 786.35413802126 -1.39488341691754 0.163757948252639 -8200.36647674309 1004.87774039016 -8.16056137690859 3.57117013068363e-15 KIF1B other 4.14291194434382e-29 3.46796331390687e-11 1 -1.39488341691754 -8.16056137690859 0.305986648162444 -12.7785396418686 30.3291211333697 -0.421329044968896 0.673724375906478 -77.2204589078322 51.9518406936739 -1.4863854269024 0.137906632569333 FOXC1 other 1 1 1 -0.421329044968896 -1.4863854269024 7.59151564841297e-07 56.6070908207854 28.3636173395859 1.99576415599787 0.0465798254843449 -99.2375147786763 41.4610252347153 -2.39351328668025 0.0171088084417821 TBC1D22A other 0.00464145266743969 1 1 1.99576415599787 -2.39351328668025 1.79503542390931e-08 -84.3498702450126 444.305276035019 -0.189846654529406 0.84951744609482 -1686.79251816376 505.712191430703 -3.33547924441308 0.000924178024576872 SYNE2 other 0.000121093089696922 1 1 -0.189846654529406 -3.33547924441308 0.00161743841829626 -923.953217957738 525.460279851248 -1.75836928762589 0.0793846534943203 -1885.3609748644 598.626615464341 -3.14947736395244 0.00174786090007442 PLEKHH1 other 1 1 1 -1.75836928762589 -3.14947736395244 2.26347639291275e-06 -334.418356456776 163.336138468349 -2.04742416217694 0.0412138386642177 -820.487560032017 189.406954257678 -4.33187663698868 1.83578194277682e-05 GALC other 0.0133499837653994 0.15332450786072 1 -2.04742416217694 -4.33187663698868 2.8021451358947e-94 458.338333466105 104.658977248252 4.37935039608617 1.49074163227272e-05 -1404.30532143711 133.730278720146 -10.5010274028955 3.69955916005165e-23 SZRD1 other 2.75843167177474e-90 3.63703661024677e-19 0.128576465783522 4.37935039608617 -10.5010274028955 0.000254900901367926 74.337174651953 29.9995708171718 2.4779412713932 0.0135902652109828 -85.6653396656889 54.5284888880994 -1.57101987259333 0.116900110289322 FAM114A2 other 1 1 1 2.4779412713932 -1.57101987259333 0.00254612850118739 -68.0948705482164 571.785072203369 -0.119091724948001 0.905257412268027 -3217.8528169442 1049.24273062755 -3.06683355816018 0.00229772736261112 CYFIP2 other 1 1 1 -0.119091724948001 -3.06683355816018 0.00285364067013714 -69.0908314363776 208.534009876012 -0.331316850797896 0.740563983625046 -621.51566634363 265.592707766243 -2.34010817379311 0.0197273437067965 TAB2 other 1 1 1 -0.331316850797896 -2.34010817379311 8.62161063234104e-25 -47.419094412767 61.8633512245977 -0.766513508791494 0.443784681700612 -582.462063602965 78.7902892818496 -7.39256155691185 7.4004512352269e-13 GINM1 other 7.62322812111595e-21 7.11849404316475e-09 1 -0.766513508791494 -7.39256155691185 1.18357228166205e-13 408.389740111885 51.8320356974127 7.87909898997601 2.63291678024101e-14 -22.9349374445714 145.664729491829 -0.157450177023518 0.87496262721883 USP36 essential 9.31056784078572e-10 1 2.54840015159527e-10 7.87909898997601 -0.157450177023518 5.76555770058903e-44 128.47143016885 79.9386166819203 1.60712601119987 0.108747335721521 -721.138805024412 96.2768302718439 -7.49026326467364 3.82449445152463e-13 MRPL43 essential 5.43692091165545e-40 3.68413550515368e-09 1 1.60712601119987 -7.49026326467364 0.125888068800905 20.5350690342116 25.3878024212892 0.808855713206266 0.419037281071916 -39.9627706822348 39.1589609052458 -1.0205268413259 0.308042004910805 ITIH4 other 1 1 1 0.808855713206266 -1.0205268413259 4.15138739059216e-16 93.7897512338649 29.4486008028461 3.18486273292823 0.00155212377818683 -131.043162506121 39.8944477665028 -3.284746871873 0.00110307397577687 HPF1 other 3.39625002424344e-12 1 1 3.18486273292823 -3.284746871873 0.00445367537747644 -12.1563820794621 207.066105683609 -0.0587077350942053 0.953211919522802 -1302.53624260355 446.786108577487 -2.91534633149331 0.00373693296329512 ZFR other 1 1 1 -0.0587077350942053 -2.91534633149331 3.68571946809542e-12 160.404565579073 51.9694058746188 3.08651913331594 0.00215455334900054 -232.566792264766 76.3378836585949 -3.04654492787451 0.00245574917149174 PHF21B other 2.80667537495466e-08 1 1 3.08651913331594 -3.04654492787451 0.468351517065394 49.5277475715738 41.3698310312738 1.19719482378676 0.231878162047346 17.255596270473 84.8145090983243 0.203450995046954 0.838877030092578 TRAF1 other 1 1 1 1.19719482378676 0.203450995046954 0.000561584757014642 323.31125894383 103.726178672013 3.11696876413577 0.00194750558093861 -196.450918217843 212.654601321947 -0.923802809798729 0.356097627767946 RC3H2 other 1 1 1 3.11696876413577 -0.923802809798729 0.01810867837788 32.4139465491511 88.7384201514667 0.365275226827614 0.715082291415002 -280.072173305622 136.872986004911 -2.04621950233169 0.0413313447671898 IL17RB other 1 1 1 0.365275226827614 -2.04621950233169 0.000168300185794128 -64.2774305030974 73.0383408938915 -0.880050528481722 0.37931453290518 -340.074671400512 99.6481263315407 -3.41275530127927 0.000702865992279819 TRAF3IP2 other 0.810533694784519 1 1 -0.880050528481722 -3.41275530127927 0.353453635123289 63.6955198904688 117.999586627404 0.539794432429617 0.589613753850583 -212.647219898077 228.474563607743 -0.930726014048376 0.352509176168791 DCBLD2 other 1 1 1 0.539794432429617 -0.930726014048376 0.117020263741105 6.12654231937685 5.25945173407903 1.16486330308527 0.244720146564691 -4.52893422265973 7.53973006135281 -0.600675910915454 0.548372333181065 F7 other 1 1 1 1.16486330308527 -0.600675910915454 6.7805384272964e-46 1249.98455921894 109.855698649267 11.3784225542065 1.85417757279746e-26 -803.115179640415 231.444464273282 -3.47001248080024 0.000572009556095272 GDI2 other 6.42116989064969e-42 1 1.82098779424438e-22 11.3784225542065 -3.47001248080024 0.634777197470836 -11.2500792256037 29.8561594086253 -0.376809323383823 0.706498209733841 -34.1277692950342 39.7449746771944 -0.85866878950653 0.390994007947574 PRDM1 other 1 1 1 -0.376809323383823 -0.85866878950653 2.36536175268294e-18 19.9856889746781 23.3094095099591 0.857408634317359 0.39168905501898 -171.034326294258 31.0298413816091 -5.51193040888785 6.07788732156082e-08 ATG5 other 1.98974230635689e-14 0.000553830044800143 1 0.857408634317359 -5.51193040888785 5.40790491111565e-20 105.997654920533 108.490378540942 0.977023551268479 0.329098033154415 -613.327099930243 138.683790551471 -4.4224858398474 1.23297116337621e-05 PITHD1 other 4.61943237507499e-16 0.103918535832676 1 0.977023551268479 -4.4224858398474 0.00353122554410449 1186.43030470151 500.99360245299 2.36815460096188 0.0183123961611812 -1182.34780681885 1023.60644531494 -1.15508046303389 0.24869012093777 SEC61A1 essential 1 1 1 2.36815460096188 -1.15508046303389 3.42768813784177e-05 219.825233537372 160.878830021008 1.36640248756575 0.172513714409404 -688.335603746821 256.170128514527 -2.6870252505174 0.00748352564482847 PPP1R12A essential 0.180193565406342 1 1 1.36640248756575 -2.6870252505174 0.0193369033976402 -512.088550951753 269.553693602778 -1.89976454823276 0.0581220825980808 -1375.22944462015 493.990050425674 -2.7839213430212 0.00560369486971692 RASGRF1 other 1 1 1 -1.89976454823276 -2.7839213430212 4.32286050889719e-33 206.03299609655 65.607009030714 3.14041135452609 0.00180135621633405 -354.283549749065 83.8307791109156 -4.22617508159284 2.89415724756349e-05 CROCC other 3.9610370843025e-29 0.239433629090927 1 3.14041135452609 -4.22617508159284 1.62469310761764e-09 76.2003340050724 29.9047184166271 2.54810404644054 0.0111714655343097 -40.3710951905717 38.3986612105458 -1.05136725911382 0.293669649264987 YIPF1 other 1.14654592604577e-05 1 1 2.54810404644054 -1.05136725911382 3.5348585701649e-36 158.558377479914 35.3445322739366 4.48607938141641 9.28140339229996e-06 -151.491967099364 45.383564610911 -3.33803588145086 0.000915758642539606 NDC1 other 3.26762326226044e-32 1 0.0807203653028328 4.48607938141641 -3.33803588145086 1.33850912993867e-17 898.773228975448 122.873529237543 7.31462044390304 1.2395338689447e-12 368.909483832245 155.51383202762 2.37219724459446 0.0181138505766966 ALDH18A1 other 1.1152458070649e-13 1 1.19317530224617e-08 7.31462044390304 2.37219724459446 0.218377686674091 -4.5916391648449 85.4079106909814 -0.0537612866032766 0.957149865597944 -324.984808853543 191.638914514659 -1.69581845981853 0.0906308759713779 TARBP1 other 1 1 1 -0.0537612866032766 -1.69581845981853 1.9698051609069e-15 360.847034120733 68.7155380589768 5.25131643167849 2.36300552337117e-07 -62.8952370953644 90.7525863660173 -0.693040712269064 0.488652152193751 GATB other 1.59514821930241e-11 1 0.00214820832129673 5.25131643167849 -0.693040712269064 3.77478814459805e-06 70.298217467729 80.8796832132589 0.869170286960333 0.385231113350058 -487.947764159128 135.334299833535 -3.60549960179582 0.000347470271354677 CDK17 other 0.0218673477216565 1 1 0.869170286960333 -3.60549960179582 0.0350254764061559 15.2306592306594 13.8678759015947 1.09826907442314 0.272690370080955 -49.8848848848845 28.6863080011442 -1.73897891924241 0.0827410689464795 DNAJC25 other 1 1 1 1.09826907442314 -1.73897891924241 5.14916520954178e-11 -648.287756927016 530.702346645989 -1.22156564979251 0.222528994042867 -3121.84450239262 638.370690290395 -4.89033182424539 1.41599077511793e-06 PSD other 3.81965075243809e-07 0.0124281510332101 1 -1.22156564979251 -4.89033182424539 7.19259534465921e-16 103.666708850349 29.831540341879 3.47507060186284 0.000563867072478527 -156.052792876019 44.8310633203628 -3.48090768583529 0.000552060293486493 CTDP1 other 5.86052668682832e-12 1 1 3.47507060186284 -3.48090768583529 0.00111849007994 138.078376092473 81.393200025012 1.69643626310358 0.090513801064789 -59.4684635499394 98.8268592527773 -0.601743938839867 0.547655931978985 CCAR1 essential 1 1 1 1.69643626310358 -0.601743938839867 0.0725649117886853 -2.12362455985937 16.1287688350453 -0.131666873124566 0.895308247165697 95.2718419894356 44.8437625503513 2.12452828601219 0.0341854748471434 GNA15 other 1 1 1 -0.131666873124566 2.12452828601219 1.94895483695626e-37 2.32021335196424 16.9838201912804 0.136613160398121 0.89139977608003 -163.680181644744 21.7288103861172 -7.53286437389692 2.89868186471503e-13 PIGV other 1.80804540224433e-33 2.79374958121234e-09 1 0.136613160398121 -7.53286437389692 0.0540425460547574 -37.8736780721524 57.1256603350148 -0.662988888881832 0.507686417942308 50.475215439872 73.3549137661617 0.688095900443359 0.491756640750156 PTPRU other 1 1 1 -0.662988888881832 0.688095900443359 1.57362834040362e-80 211.386796151323 28.6895798371597 7.36806873265981 8.71556958314923e-13 -221.507101556031 36.855503534105 -6.01014991834406 3.91194479180696e-09 SNRNP40 essential 1.54577511877848e-76 3.63458790606784e-05 8.39396506553102e-09 7.36806873265981 -6.01014991834406 0.127124833470109 -40.9652665741953 74.3617615147141 -0.550891556893652 0.581990180162599 -281.069693092907 138.075352630105 -2.03562538671094 0.0423921035529826 RIMBP2 other 1 1 1 -0.550891556893652 -2.03562538671094 8.99721021043726e-22 463.236353273708 125.191024773012 3.70023613205193 0.000242826892357142 -340.499111047352 161.522172017577 -2.10806421678319 0.0355929354546406 COL11A1 other 7.80957846265954e-18 1 1 3.70023613205193 -2.10806421678319 8.80347404070781e-08 405.414019162885 126.553139583632 3.20350819028846 0.00145768301369112 -263.312830386959 159.025538122961 -1.65578958886064 0.0984872623078091 QSER1 other 0.000570112978876238 1 1 3.20350819028846 -1.65578958886064 2.61142812280743e-13 -199.177118574128 156.647693544219 -1.27149729477443 0.204226549090325 -1148.94156558571 200.136861825237 -5.74077936022096 1.7629807777205e-08 MPC1 other 2.03874193547576e-09 0.000162264750781394 1 -1.27149729477443 -5.74077936022096 5.89169086207771e-10 461.961449708157 127.571023581565 3.62120986991057 0.000327531848024451 -584.858784670378 217.01626088401 -2.6949998229993 0.00730965706700508 ACAA1 other 4.23553656074767e-06 1 1 3.62120986991057 -2.6949998229993 0.0129667379688337 270.844003970899 92.7277948401961 2.92085026326424 0.00367113111667864 194.84800252191 141.58371798721 1.37620345963447 0.169461835002063 HDAC7 other 1 1 1 2.92085026326424 1.37620345963447 0.840517665334608 -76.6459334664019 129.999674994534 -0.589585577576442 0.555773912517889 -75.5251784211939 177.403766037124 -0.425724775230472 0.670518474887061 GUCY1B3 other 1 1 1 -0.589585577576442 -0.425724775230472 1.88498240357149e-06 449.31421690032 86.9373778882397 5.16825130702613 3.5983124015985e-07 148.647310394628 158.543741627794 0.937579174481703 0.348977410347647 SFSWAP essential 0.011177945653179 1 0.00326079069832856 5.16825130702613 0.937579174481703 0.000254386710807483 140.760398288459 1276.80887737013 0.110243906338109 0.912266668120358 -7443.08464776941 2221.72119334675 -3.350143424863 0.000877942445257417 TNK2 other 1 1 1 0.110243906338109 -3.350143424863 1.17746510368595e-08 62.151987698251 75.7994472415535 0.819953046625637 0.412692956278225 -585.237137215088 125.075560010633 -4.67906869387861 3.85654319151641e-06 MON2 other 8.01618242589396e-05 0.0332703981132121 1 0.819953046625637 -4.67906869387861 0.76780795689423 47.9054999785336 74.8875352331801 0.639699248070702 0.522703352793726 -16.8410759520837 172.84114676665 -0.097436728852653 0.922424250348564 CDH3 other 1 1 1 0.639699248070702 -0.097436728852653 1.15987069018498e-36 128.237633742479 15.1870125467781 8.44390121806309 4.62411925117579e-16 26.2906162391458 19.4376010030786 1.35256486821505 0.176897332041325 ZNF112 other 1.07415624618031e-32 1 4.49140702866704e-12 8.44390121806309 1.35256486821505 2.27719569349026e-10 101.611362621945 194.694135882579 0.521902532715354 0.602003225374065 -1632.8004812452 313.970622902225 -5.20048807799983 3.06311890737006e-07 CS other 1.65643214744481e-06 0.00274669872423874 1 0.521902532715354 -5.20048807799983 0.323897160237784 -9.15591533952091 9.76921421588684 -0.937221268485589 0.349163603696334 -22.6293416086174 15.0513120421046 -1.50347966644463 0.133439367839746 LTK other 1 1 1 -0.937221268485589 -1.50347966644463 2.46476366593712e-16 147.909168967005 82.9531631605759 1.78304435095129 0.0752730836466941 -354.326434645097 99.8638731324889 -3.54809425601803 0.000430048706316959 WAPL other 2.02184563516822e-12 1 1 1.78304435095129 -3.54809425601803 3.6236449401245e-31 365.815274890278 54.8799797569683 6.66573268631407 7.9416392464081e-11 57.9530616088902 67.1212065278558 0.863409116235705 0.388385106476768 POLD1 other 3.29389325057317e-27 1 7.56202889042979e-07 6.66573268631407 0.863409116235705 0.318195522346004 -238.888307774521 474.913567794106 -0.50301428296546 0.615208230943599 -1564.91327963134 1038.30802248094 -1.50717633471821 0.132489655433309 SEZ6 other 1 1 1 -0.50301428296546 -1.50717633471821 5.67589202339126e-05 28.9881210289891 567.544391943577 0.0510763940944217 0.959287930705778 -3348.13418407954 917.68970913614 -3.64843819293918 0.000295624072795397 EIF4B essential 0.290151600235761 1 1 0.0510763940944217 -3.64843819293918 2.24139785059048e-05 11.6640288621399 5.08257141471193 2.29490702843394 0.0222104950777812 0.945291027165443 6.20172113801 0.15242398136411 0.878922731611936 SLC6A16 other 0.12013892479165 1 1 2.29490702843394 0.15242398136411 1.00995521888703e-51 140.540257101147 29.2466779423073 4.80534087934294 2.13210488740924e-06 -128.365976103417 35.754627504138 -3.59019195735044 0.000368168678767337 BICRA other 9.67234113128108e-48 1 0.0189458840295185 4.80534087934294 -3.59019195735044 7.72675147252172e-44 197.808907635746 53.311765507244 3.71041749890778 0.000233552639304318 -248.393262316361 65.0214734258661 -3.82017277107025 0.000152626024114582 SPHK2 other 7.28400861314623e-40 1 1 3.71041749890778 -3.82017277107025 1.97159322377147e-25 1855.44703898082 1022.53182798949 1.81456164805061 0.0702752535656045 -4469.69556796405 1247.12669798352 -3.58399477389996 0.000376397746581725 RPL18 essential 1.74821171151816e-21 1 1 1.81456164805061 -3.58399477389996 0.525927299257744 -361.419219912228 447.290185030089 -0.808019563156557 0.419517940165878 -190.524867615855 545.535616816756 -0.34924368225045 0.727074213876022 CA11 other 1 1 1 -0.808019563156557 -0.34924368225045 2.02602443511826e-35 354.177868288541 60.5836407106231 5.84609746350943 9.90275949748635e-09 -39.9724515486843 75.008905710155 -0.532902742284277 0.594373661250987 ISOC2 other 1.86839973406606e-31 1 9.21946909215979e-05 5.84609746350943 -0.532902742284277 3.60642920155262e-61 1123.32053989685 182.049035404461 6.17042840903357 1.55746588300658e-09 -765.335309314524 228.988127990899 -3.34224885818073 0.00090264925015867 U2AF2 essential 3.49499053922465e-57 1 1.46479666296768e-05 6.17042840903357 -3.34224885818073 5.69689771244079e-31 505.623858492559 214.762324612243 2.35434152338158 0.0189982171045302 -1033.46679869115 270.136134293004 -3.82572587482947 0.000149426152224787 EPN1 other 5.17278312289624e-27 1 1 2.35434152338158 -3.82572587482947 1.38472823885755e-46 1197.35611008976 143.566539712324 8.34007779590567 9.73178596559556e-16 -317.161194799808 203.110176607907 -1.56152291380294 0.119122629966187 MED29 other 1.31355320738027e-42 1 9.44761781540017e-12 8.34007779590567 -1.56152291380294 7.74149835118059e-07 41.2989730099654 10.4497247300136 3.95215893978019 9.04572138245756e-05 -7.52870774778381 16.0709016012179 -0.468468287256097 0.639686030167781 AHRR other 0.00472928134273622 1 0.753237219517241 3.95215893978019 -0.468468287256097 0.0217490728901984 710.476589452934 626.123119420399 1.13472345520578 0.257111808101092 -878.641042098866 921.176635773377 -0.953824715019178 0.340698468781727 GPC1 other 1 1 1 1.13472345520578 -0.953824715019178 4.97791185398149e-22 22.9527878898639 35.585206913717 0.645009257513024 0.519258883860786 -210.361392609666 41.0752696374921 -5.12136364450437 4.55377337333562e-07 ADCK1 other 4.33377006007629e-18 0.00406424273570204 1 0.645009257513024 -5.12136364450437 3.02568590513317e-07 86.6140294040545 72.5817867303287 1.19333008053193 0.233387574768103 -459.408864411222 119.40972238429 -3.84733215384868 0.000137200334920583 RNF4 essential 0.00189589478815644 1 1 1.19333008053193 -3.84733215384868 4.90648963868631e-06 233.357091111708 457.128870245911 0.510484255755218 0.60997000074885 -2879.11812018206 744.17821545734 -3.86885568588255 0.000126004480910535 LIMCH1 other 0.0281436245675047 0.993545331979568 1 0.510484255755218 -3.86885568588255 1.3785365491748e-06 4.97613200928279 7.00799425917628 0.710065080713648 0.478042505592183 -20.8184594082249 8.00705751380145 -2.6000137219373 0.00963774182759142 TSPAN32 other 0.00826019100265542 1 1 0.710065080713648 -2.6000137219373 0.148273985189625 -121.865723485723 97.2152205341595 -1.25356629153458 0.210669918658391 -360.661988793399 188.231210993195 -1.91605837783426 0.056009777433695 ST3GAL6 other 1 1 1 -1.25356629153458 -1.91605837783426 0.253350558224827 -6.87263777449324 9.98380007572544 -0.688378946129273 0.49157860251083 -37.0662346917232 22.3565310269348 -1.65796002282583 0.0980415027327087 ATP2C2 other 1 1 1 -0.688378946129273 -1.65796002282583 0.331677468379575 296.997190613041 315.042091346421 0.942722254489043 0.346342667659144 961.973903630294 749.714730521061 1.28311991810766 0.200128574485936 NGFR other 1 1 1 0.942722254489043 1.28311991810766 3.02547331703311e-64 95.7759223943636 20.1798145719441 4.746124997973 2.81215353271855e-06 -171.329779297809 25.9128480801956 -6.61176952713088 1.10747596377665e-10 DDX20 essential 2.94045751682448e-60 1.04634329057618e-06 0.0249241167604845 4.746124997973 -6.61176952713088 2.27452575586799e-09 207.049600216018 111.687493604465 1.85382976673532 0.0644387144860244 -957.401731147156 218.972458297467 -4.37224726155541 1.53951926634355e-05 BTBD1 other 1.5971719857705e-05 0.129042504904917 1 1.85382976673532 -4.37224726155541 1.07268088534876e-05 204.381247601001 453.552535058057 0.450623096120143 0.652484197566714 -1294.42270850753 585.176059701431 -2.21202266744811 0.0274804605570481 CHI3L2 other 0.0594157942394681 1 1 0.450623096120143 -2.21202266744811 1.20739269951174e-12 623.138194241501 82.9639309709792 7.51095309670747 3.3252658942346e-13 254.134353386492 229.405990812191 1.10779301136275 0.268559183553095 HMG20B other 9.28484985924529e-09 1 3.206221375221e-09 7.51095309670747 1.10779301136275 6.50766046595123e-14 154.97637928841 24.8920016232735 6.2259508750598 1.1221822694724e-09 -138.501357024723 58.4407982319097 -2.36994293738273 0.0182232231956694 TAF11 other 5.13909946996169e-10 1 1.05754457075079e-05 6.2259508750598 -2.36994293738273 0.0509449498386658 -49.7258810058939 67.5475375896288 -0.736161269238167 0.462026626245448 -386.838231344445 158.586363406266 -2.43929063656906 0.0151121132578501 ANKS1A other 1 1 1 -0.736161269238167 -2.43929063656906 8.73059536938592e-09 96.4807684152491 40.6247755180927 2.37492434566882 0.017982310655007 -420.627376560226 95.3777982663194 -4.41011833158201 1.3016683795052e-05 ZNF76 other 5.98395006617711e-05 0.109561427502953 1 2.37492434566882 -4.41011833158201 7.2627988526964e-05 83.6333488825751 48.7091940879045 1.71699307386699 0.0866873657804555 -354.815798029488 114.358187292927 -3.10267070883724 0.00204192900234048 UHRF1BP1 other 0.36648083010706 1 1 1.71699307386699 -3.10267070883724 7.11309160567614e-25 1272.47396714953 213.598432337078 5.95731884933242 5.28011438531702e-09 -838.781117358348 282.751191591062 -2.96649896553385 0.00317732956916711 IPO5 other 6.29224083438112e-21 1 4.93479490451728e-05 5.95731884933242 -2.96649896553385 3.24143602859526e-27 229.323845241681 193.958567547557 1.1823341868384 0.237716038387658 -1143.92582065955 225.199463468888 -5.07961166087584 5.61271796356227e-07 OAT other 2.90238182000419e-23 0.0049891449978105 1 1.1823341868384 -5.07961166087584 1.97783665198521e-37 141.909886376383 64.8667481998759 2.18771389524741 0.0292219334653302 -445.159722110934 81.6127718830062 -5.454535017498 8.25302462707e-08 WDR3 essential 1.83464127838148e-33 0.000750777650324558 1 2.18771389524741 -5.454535017498 1.3170211113714e-67 184.053553854282 57.2398693752945 3.21547822982492 0.00139869308595952 -629.483828693966 73.8552797539114 -8.52320688231674 2.53157835801396e-16 PKN2 other 1.2837004772537e-63 2.46828889906362e-12 1 3.21547822982492 -8.52320688231674 0.000436448366738572 414.562437606492 104.726762756276 3.95851477402466 8.80428894279826e-05 341.214481307005 236.793954000529 1.44097632368706 0.150309136343211 TRAM2 other 1 1 0.734101612050519 3.95851477402466 1.44097632368706 0.00026719645712795 1048.77802529463 270.331711882525 3.87959672948169 0.000120707408175112 242.319188943184 204.004610291397 1.18781231756017 0.235551074781896 NTN1 other 1 1 0.998612387832702 3.87959672948169 1.18781231756017 0.664463891920052 -7.110559333137 10.8928368647632 -0.652773875292179 0.514244531771325 5.32077053124203 8.15283106203113 0.652628576596122 0.514338132433689 GLP2R other 1 1 1 -0.652773875292179 0.652628576596122 8.52485606145902e-06 100.2150121241 21.4925232470088 4.66278486580432 4.14831911531265e-06 169.617143242307 43.9545884781873 3.85891778571605 0.000131020886505987 MCM10 other 0.0477391939441705 1 0.0365549880441351 4.66278486580432 3.85891778571605 0.188767049773397 61.2971269184111 33.5160809005986 1.82888706767969 0.0680994429266235 60.8022426797085 53.8769500062061 1.12853906304467 0.259712912774352 DGKA other 1 1 1 1.82888706767969 1.12853906304467 0.235770577058819 513.909618595098 385.924565110791 1.33163230603775 0.183676794974013 -31.4152561962239 614.587775177972 -0.0511159796289907 0.959256512177627 ERBB3 other 1 1 1 1.33163230603775 -0.0511159796289907 5.24898779503813e-09 570.888583573052 109.54103948038 5.21164110073381 2.89193816957135e-07 -376.774651868394 252.821765636254 -1.49027774930769 0.136872619208633 KARS essential 3.62810036393036e-05 1 0.00262559066415382 5.21164110073381 -1.49027774930769 0.086950668519427 42.765188270148 26.5780312700254 1.60904274043723 0.108329131023224 -52.5972335523019 61.3423500881324 -0.857437536656712 0.391673105314045 ADAT1 other 1 1 1 1.60904274043723 -0.857437536656712 7.01010589943454e-06 86.2251388829985 18.7755241737913 4.59242245834925 5.73429518403578e-06 3.25889487299086 44.080690518394 0.0739302137662974 0.94109966527598 TBC1D22B other 0.0395369972728108 1 0.0502553629928896 4.59242245834925 0.0739302137662974 0.00231673019090739 10.8851091404231 61.8342985227305 0.176036753071948 0.860346427793518 -374.345483711638 122.815488488924 -3.04803154974544 0.00244291147865732 NDUFB4 essential 1 1 1 0.176036753071948 -3.04803154974544 1.33295585648432e-25 108.63140220468 221.963098738995 0.489411991550988 0.624795611481576 -1607.94078918721 283.736533226837 -5.66702063671766 2.64131117857841e-08 SPEN other 1.18353150497243e-21 0.000242393126858141 1 0.489411991550988 -5.66702063671766 0.215645730529606 -334.451723323894 237.088344084348 -1.4106628675297 0.159053857846178 -726.439852286528 459.042796144866 -1.58251008051388 0.11425494914952 MYLK other 1 1 1 -1.4106628675297 -1.58251008051388 0.00475369294766198 -13.3680516738098 92.2967648591515 -0.144837705787521 0.884905633934706 -226.333168134654 69.0827279389966 -3.27626274883813 0.00113553001072909 MAP2K4 other 1 1 1 -0.144837705787521 -3.27626274883813 0.000933937660633664 -406.739033370441 451.006429323833 -0.901847527939325 0.367635789047274 -1974.33685034827 622.233333573423 -3.17298470496567 0.00161553016784147 SNAP91 other 1 1 1 -0.901847527939325 -3.17298470496567 1.14675744591984e-10 9.71418550272981 98.4411937573541 0.0986800863739435 0.921437528183797 -435.959989607692 117.751369678391 -3.70237722752958 0.000240913131759668 SLK other 8.42408019772714e-07 1 1 0.0986800863739435 -3.70237722752958 7.31123559801548e-07 -17.1058126914783 33.2669737539159 -0.514198039713929 0.607374056491156 -187.234204344062 45.8969509765806 -4.07944755283635 5.36806344416708e-05 CYB5R4 other 0.00447447618598548 0.435940432300809 1 -0.514198039713929 -4.07944755283635 6.703735615279e-07 -31.8850275495556 19.0307694443974 -1.67544605291524 0.0945620712614139 -95.6182675933881 22.7398582502643 -4.2048752697162 3.17027272413877e-05 GSTO2 other 0.00411274179997367 0.261547499741448 1 -1.67544605291524 -4.2048752697162 2.54331893490368e-30 257.368315239241 27.8595643023936 9.23805959223595 1.11869279156201e-18 -114.694627339946 57.4160383090478 -1.99760608216454 0.0463816723700681 SEC61A2 other 2.30450128691623e-26 1 1.0924035109603e-14 9.23805959223595 -1.99760608216454 0.103242165334506 27.4162540819551 22.0086704548964 1.24570242160429 0.213541124411619 -35.1530764295225 46.2818256150647 -0.759543859006293 0.4479368154581 PRKCQ other 1 1 1 1.24570242160429 -0.759543859006293 2.56235350699966e-14 -3.80134146340735 112.283151266759 -0.0338549588297201 0.973008267925571 -1002.47232349165 169.822830932028 -5.90304800591209 7.16942781940033e-09 ASB1 other 2.03912092087033e-10 6.63602238963694e-05 1 -0.0338549588297201 -5.90304800591209 0.0011035526712253 309.241347281515 135.11702525353 2.28869268473948 0.0225725326060302 -320.052681653834 277.736620129948 -1.15236039634992 0.249801561333782 FAM107B other 1 1 1 2.28869268473948 -1.15236039634992 0.128945389332455 -129.913646018918 74.1578355576423 -1.75185326057605 0.0805004720087631 -202.006475263814 102.305022448055 -1.97455091089376 0.0489482725734621 ME1 other 1 1 1 -1.75185326057605 -1.97455091089376 0.00198065941422267 191.795562901283 117.985295286284 1.62558870099789 0.104758091978437 -325.471029987109 191.393468205677 -1.70053363387171 0.0897420522723087 TBC1D1 other 1 1 1 1.62558870099789 -1.70053363387171 3.86818667877875e-47 1740.19415906751 361.168454065385 4.81823409403434 1.99968087992723e-06 -2061.55075196217 463.802622891386 -4.44488808431112 1.11564142534867e-05 YBX1 essential 3.67206961416467e-43 0.0942828568562162 0.0177891611078326 4.81823409403434 -4.44488808431112 0.00273614058520805 -125.901792898162 101.457876145481 -1.24092675385428 0.21529703723984 90.292575288255 130.908751325634 0.689736739323509 0.490725021588849 TIE1 other 1 1 1 -1.24092675385428 0.689736739323509 0.00103515478013145 -115.855415924972 301.245262905411 -0.384588341099823 0.700729093439648 -1473.88703206781 460.277957022935 -3.20216731994048 0.00146339135124968 DIP2B other 1 1 1 -0.384588341099823 -3.20216731994048 9.47683577085851e-09 155.709517045454 155.136675842008 1.00369249373391 0.316082286931831 -1018.0351710464 237.051467090247 -4.29457443795877 2.15834934375055e-05 SMARCD1 other 6.47552188222762e-05 0.17953149841317 1 1.00369249373391 -4.29457443795877 1.39793819616581e-47 236.062293887503 78.4143793374355 3.01044650078363 0.00275942118660944 -636.775254068723 101.176260286772 -6.29372198837811 7.53091261546271e-10 KDM4A other 1.32832087399676e-43 7.06399603330402e-06 1 3.01044650078363 -6.29372198837811 4.96431890111622e-74 282.020154094778 37.5334151721204 7.51384207382922 3.26087506859052e-13 -243.554272699678 48.1993823296353 -5.05305796315007 6.39717140203781e-07 NFYC other 4.85808247663234e-70 0.00567812933644876 3.14446182864184e-09 7.51384207382922 -5.05305796315007 5.00960898362386e-06 11.3969265268666 11.610736859219 0.981585119450656 0.326846155673171 -26.9029371355779 14.9101898252513 -1.80433230233032 0.0718660324405851 ZMYND12 other 0.0287050594761647 1 1 0.981585119450656 -1.80433230233032 0.00566268528715358 -4.71987743965392 26.2178098795837 -0.180025618513977 0.857216096174286 -104.065943712558 39.6476966446331 -2.62476644344091 0.0089754246732255 SLC9A3 other 1 1 1 -0.180025618513977 -2.62476644344091 0.20161951267647 -191.89479023692 279.311939745181 -0.687026807418214 0.492431929311671 -722.421523675017 430.836664777815 -1.67678747593958 0.0943024699507741 NGEF other 1 1 1 -0.687026807418214 -1.67678747593958 0.194384012172858 -58.4236357647394 111.319493241355 -0.524828438071213 0.59996920926518 169.88604054146 146.701854507193 1.15803608013101 0.247483261422811 SPI1 other 1 1 1 -0.524828438071213 1.15803608013101 1.97938531422571e-09 117.077872480337 21.5091618194871 5.44316293972297 8.73237882135177e-08 -47.0684471871659 46.0754783306433 -1.02155091802622 0.307557389761493 ZNRD1 essential 1.39309138415206e-05 1 0.000799973223824035 5.44316293972297 -1.02155091802622 0.00517747048545703 68.6808508683267 39.8085663645211 1.72527817855651 0.0851859444918405 -49.6654507029311 49.9133218524771 -0.995033968080133 0.320271644057144 MPPED2 other 1 1 1 1.72527817855651 -0.995033968080133 0.0122033037983519 9.14857942964519 37.1150804256162 0.246492243172697 0.805416687069907 -189.65564240265 74.4200294181838 -2.54844890394937 0.0111605913930825 ZBTB11 essential 1 1 1 0.246492243172697 -2.54844890394937 7.95101319888287e-26 66.9438330517406 33.6188573851767 1.99125842632765 0.0470746260538114 -192.304602949903 39.7326358359414 -4.8399659097358 1.80420783491815e-06 ATXN3 other 7.0668605311671e-22 0.0157687764771847 1 1.99125842632765 -4.8399659097358 5.757435541353e-23 32.1780076211216 64.6731283231844 0.497548339711073 0.619052107904952 -434.263680431343 76.320489548519 -5.6900012434442 2.3276857611091e-08 GOLGA5 other 5.03948332934628e-19 0.000213821214015482 1 0.497548339711073 -5.6900012434442 0.480005745907599 245.721893098195 297.637369104944 0.825574738270033 0.409495828196697 403.265449724654 345.796967256457 1.16619140105291 0.244173121418772 FGFR2 og 1 1 1 0.825574738270033 1.16619140105291 1.27028061585462e-42 53.1992339666959 25.3103023762076 2.1018806166735 0.0361355265495841 -211.624682510964 32.5182646521056 -6.50787133861589 2.09299577537978e-10 LRRC40 other 1.19406377890335e-38 1.9751601132259e-06 1 2.1018806166735 -6.50787133861589 4.1849400144128e-07 -37.4087568540793 53.500452532731 -0.699223185657972 0.48478370230089 -243.492413454456 63.3323295941573 -3.84467798697428 0.000138601433425951 EML1 other 0.00260094021895756 1 1 -0.699223185657972 -3.84467798697428 2.52715017077862e-17 12.6079342887115 24.4770059202839 0.515092995024503 0.606748481906292 -168.503540220701 31.7263336094696 -5.31115704369968 1.73829649083442e-07 TRMT11 other 2.09854550181456e-13 0.00156690045683815 1 0.515092995024503 -5.31115704369968 2.6393698887592e-18 186.232871799669 21.0297478255141 8.85568735036016 2.08669788798284e-17 12.5625981018912 46.156413223403 0.272174487239435 0.785616112167545 MSANTD3 other 2.21786251752436e-14 1 2.03223507310649e-13 8.85568735036016 0.272174487239435 0.0102700344369002 368.727719811255 145.804940184063 2.52891101869233 0.0118223468433102 165.062205090715 164.389704682674 1.00409089127168 0.315937305169254 KIF26A other 1 1 1 2.52891101869233 1.00409089127168 1.98345319407269e-18 -56.7434602824691 81.381165812176 -0.697255436392131 0.486014567571512 -602.942859196684 96.8665197427144 -6.22447116710862 1.13614120809597e-09 ATG2B other 1.6698692440898e-14 1.06354178489864e-05 1 -0.697255436392131 -6.22447116710862 5.35932152826488e-14 94.8830963198985 31.7206946319557 2.99120487179724 0.00293561682534017 -192.772103223777 50.6751280015689 -3.80407728260318 0.000162555826071049 FECH other 4.23975926101034e-10 1 1 2.99120487179724 -3.80407728260318 0.107140386539304 -12.1567205842437 94.0655737315425 -0.129236660150909 0.897229848874477 -294.961236684071 163.197813712807 -1.80738473128776 0.0713898463659631 MYO9A other 1 1 1 -0.129236660150909 -1.80738473128776 1.57201710474649e-07 453.621997575551 204.080564664527 2.22275942013992 0.0267441822784621 -1385.62554079507 434.630948338083 -3.18805079595309 0.00153550130867567 PFKP other 0.00100216090427589 1 1 2.22275942013992 -3.18805079595309 7.633711065248e-19 267.464288711709 110.19714915231 2.42714344943744 0.0156290414387054 -1569.34816369033 236.033971600442 -6.64882327340118 9.00741751622034e-11 IDI1 other 6.45506607677371e-15 8.52011622859282e-07 1 2.42714344943744 -6.64882327340118 0.815080129064335 40.1907891557532 76.6826531262506 0.524118395976505 0.600461310264133 0.226955555227888 141.271191645619 0.00160652396701806 0.998718911305887 SP100 other 1 1 1 0.524118395976505 0.00160652396701806 0.000687773503752624 223.10234994952 121.234372497093 1.84025656547914 0.0664100449061332 990.607782578992 258.193181581014 3.83669226473421 0.000143120252219063 KLF6 other 1 1 1 1.84025656547914 3.83669226473421 0.150892386779994 -214.792565712049 249.768723649156 -0.859965821876736 0.390279406482877 -834.687132208716 433.332918903062 -1.92620291650503 0.0547273483419084 NEO1 other 1 1 1 -0.859965821876736 -1.92620291650503 0.420528209020327 -104.788737462334 111.037727386072 -0.943721921631103 0.345833218537061 -283.316183151172 260.522141483 -1.08749368302601 0.277418120329211 CACNB1 other 1 1 1 -0.943721921631103 -1.08749368302601 5.54187353501346e-55 75.1575029369721 42.0332149051584 1.78805030989311 0.0744590263875362 -450.271278967426 54.2314928779651 -8.30276385679909 1.27721301705131e-15 EVI5 other 5.33349909009696e-51 1.24260054428922e-11 1 1.78805030989311 -8.30276385679909 0.000972892357024436 24.7688686362674 66.3125292478005 0.373517175671428 0.708944696237613 -327.566285421131 115.048038997701 -2.8472131144076 0.00461824812275599 STOML1 other 1 1 1 0.373517175671428 -2.8472131144076 0.0173846171548361 -808.866636991826 2465.50169056967 -0.328073852103072 0.743012953534628 -10763.9103268249 4277.4893050089 -2.51640847218963 0.0122129417472095 PKM essential 1 1 1 -0.328073852103072 -2.51640847218963 8.33523322255016e-61 203.79188889254 38.9696831568445 5.22949822487195 2.64103076067983e-07 -289.942146308383 50.3001284326584 -5.76424266384443 1.55165800194257e-08 DNTTIP2 essential 8.07434042268434e-57 0.00014293873513895 0.00239937644607763 5.22949822487195 -5.76424266384443 2.65319683240368e-08 168.754896416728 225.615969369118 0.747974076873246 0.454879040461534 -1377.66115491273 338.05191453579 -4.07529463870816 5.46117109336796e-05 TP53BP1 other 0.000177074356594622 0.442955587383075 1 0.747974076873246 -4.07529463870816 2.34615873553837e-13 871.664954084391 485.469624056893 1.79550874223644 0.0732634412216791 -3909.52796350759 756.981170701407 -5.16463039613665 3.66796466087553e-07 RHOA other 1.83328843594968e-09 0.00328246157501751 1 1.79550874223644 -5.16463039613665 0.00186976683065534 217.29287634409 64.5615487439618 3.36567013294291 0.000831016530282807 -56.9137096774181 146.070145468363 -0.389632730870011 0.696997960040558 DHX8 essential 1 1 1 3.36567013294291 -0.389632730870011 0.290651527445226 -18.0766421439011 164.699548235228 -0.109755262461823 0.912653739872585 155.983496722716 210.442594230972 0.741216374435663 0.458959464080462 PRKCZ other 1 1 1 -0.109755262461823 0.741216374435663 0.375272531699577 -1238.48678977475 1345.92387837696 -0.920175954726523 0.357988478362004 -3030.80595096227 2170.36036284615 -1.39645286692748 0.163287029594737 SYT1 other 1 1 1 -0.920175954726523 -1.39645286692748 0.249598830668521 -63.9301211654883 81.3619530585893 -0.78574958887051 0.432440026507073 -219.023564665071 132.452349817009 -1.65360271046655 0.0989263814824505 NAV3 other 1 1 1 -0.78574958887051 -1.65360271046655 2.98512766115722e-05 41.4332675208678 126.837899944794 0.326663146732181 0.744083866442788 -715.253316267474 208.110843850818 -3.43688633918661 0.000646547271642111 ROCK1 other 0.158122212211498 1 1 0.326663146732181 -3.43688633918661 0.00919920974154767 237.35334996627 89.4890885213885 2.65231609672213 0.00828442705237397 -108.540013634724 206.538195724701 -0.525520295429515 0.59948748445572 CBFB other 1 1 1 2.65231609672213 -0.525520295429515 0.410975620752893 83.2473820309207 138.599187725882 0.600633982037218 0.548396604017193 -122.813841460806 209.768862168194 -0.58547222019221 0.558533839112183 HYAL2 other 1 1 1 0.600633982037218 -0.58547222019221 5.34536209775354e-08 -228.032567285225 217.391856997006 -1.04894714289306 0.294782209432061 -1562.51159263465 323.20130212833 -4.83448421261075 1.85203530526678e-06 HDAC4 other 0.000349853949297969 0.0161793804268106 1 -1.04894714289306 -4.83448421261075 0.0255393505410903 104.743411520898 40.6386626983828 2.57743253753934 0.0102819723028197 53.4346348292283 61.5063203049699 0.86876656844826 0.385453885508589 RASSF1 other 1 1 1 2.57743253753934 0.86876656844826 0.654825436526455 -728.535728328408 893.788829915191 -0.815109457563412 0.415453662954013 -196.753799575362 1389.39809325817 -0.141610817324479 0.88745268056691 FGFR3 og 1 1 1 -0.815109457563412 -0.141610817324479 0.448005196202924 -2.55779569892251 106.660470681447 -0.0239807276545933 0.980878927534136 296.599462365594 241.318722541026 1.22907770786483 0.219704072546282 IFI35 other 1 1 1 -0.0239807276545933 1.22907770786483 4.12313289840891e-05 195.762601952134 56.6256357517748 3.45713737873571 0.000599278464813409 -243.602754378928 124.024398689866 -1.96415186811812 0.0501444344291511 COASY essential 0.214732761349136 1 1 3.45713737873571 -1.96415186811812 0.0563400547856724 83.1347004423029 42.1289897458182 1.97333714726817 0.0490868024917888 -75.9965822275811 92.274154844016 -0.823595538274492 0.410618650871553 PLEKHH3 other 1 1 1 1.97333714726817 -0.823595538274492 0.00117059753917438 137.946351754524 111.348469412287 1.23887065967431 0.216056887170894 -503.867432309294 216.486024370389 -2.32748249580869 0.0203944349259398 MEF2A other 1 1 1 1.23887065967431 -2.32748249580869 4.09708578507341e-29 -1.87226803683374 63.8466935528254 -0.0293244322086103 0.976619320917986 -447.783627448889 72.8964823301048 -6.14273299802236 1.83566572342239e-09 INPP5A other 3.69475196097921e-25 1.71230898680841e-05 1 -0.0293244322086103 -6.14273299802236 3.84472581791236e-08 397.999152337122 133.692257009961 2.97697982843889 0.00307432512810835 -415.42526255532 192.944759936461 -2.15307875006362 0.0318641395409976 ATP11A other 0.000253828798498574 1 1 2.97697982843889 -2.15307875006362 5.36477078000616e-06 327.84964438122 113.625736139472 2.88534671387119 0.00410425799354307 -251.479267425321 176.891993917029 -1.42165432056398 0.155843166518132 IP6K2 other 0.0306543002369552 1 1 2.88534671387119 -1.42165432056398 0.0265839945492084 146.645556525393 57.9189020393504 2.53191188648157 0.0116952088876857 9.11608961303445 131.650426032374 0.0692446647365402 0.944826690175992 IFT80 other 1 1 1 2.53191188648157 0.0692446647365402 1.91433366794244e-09 389.128093178723 613.291113804539 0.634491653995726 0.526091268583365 -2836.35632749555 867.478989948612 -3.26965420530078 0.0011617366451943 SIRT2 other 1.34826520233186e-05 1 1 0.634491653995726 -3.26965420530078 0.0164159737472997 -98.7439775910373 92.7228480899137 -1.06493684809255 0.287491214653977 -622.443625655389 216.121612597893 -2.88006191594306 0.00417099613139795 ADGRF5 other 1 1 1 -1.06493684809255 -2.88006191594306 0.0252406966050032 -393.90572020156 423.806698985643 -0.929446658451484 0.353169602431159 297.687433511666 541.822011453922 0.549419232180792 0.582997783300046 KCNAB2 other 1 1 1 -0.929446658451484 0.549419232180792 0.0024759897272185 -54.0376138903231 87.7347533672637 -0.615920280349088 0.53826706858492 -425.551870952955 137.808544354505 -3.08799336751027 0.00214322598046034 RORA other 1 1 1 -0.615920280349088 -3.08799336751027 0.102726127152502 4.99704756226346 7.11546641725903 0.702279691763115 0.482877789347269 -5.33262375854342 8.2583490876022 -0.645725156684038 0.518795501985488 DRD4 other 1 1 1 0.702279691763115 -0.645725156684038 7.77814331912445e-08 -10.1219564414149 82.2696496187097 -0.123033907258954 0.902136682096981 -343.728656673124 106.150626375618 -3.23812179361832 0.0012946804009297 TGFBR3 other 0.000505345971443516 1 1 -0.123033907258954 -3.23812179361832 3.39130230128667e-05 -56.3213334418958 59.4315903071004 -0.947666605434366 0.343821749094925 123.702143351637 76.6789757513911 1.61324720550135 0.107411017974111 KIAA1107 other 0.1783965472972 1 1 -0.947666605434366 1.61324720550135 0.000653329594993854 325.565249507553 109.871573633439 2.96314359338955 0.00321108687863238 -271.321651346027 239.959053659187 -1.13069978902061 0.258800221022615 ATP1B3 other 1 1 1 2.96314359338955 -1.13069978902061 0.020030028723187 141.491930259335 77.4392707500943 1.82713407407911 0.0683614849637369 -55.9978636653501 118.099340609857 -0.474158986630923 0.635623361921584 NEDD4 other 1 1 1 1.82713407407911 -0.474158986630923 0.000106810690261894 -25.1539524143338 21.5439518044431 -1.16756445812073 0.243620598569585 -129.690744711559 32.8581758844837 -3.94698552857896 9.22356146784141e-05 PIGB other 0.527431188513232 0.736409147592458 1 -1.16756445812073 -3.94698552857896 2.42530746032247e-06 157.747909301605 104.657090982678 1.50728352776128 0.132462195003072 -463.676830896413 161.107856926688 -2.8780522548159 0.00419806484715894 MAPK6 other 0.0142729344039977 1 1 1.50728352776128 -2.8780522548159 0.00570257844478205 -49.7483311794447 116.693982914321 -0.42631445030007 0.670089125360865 -495.005083894952 179.637302422991 -2.75558070188209 0.00610431980477003 GNB5 other 1 1 1 -0.42631445030007 -2.75558070188209 0.486297094190218 0.114799389715802 22.3129293257935 0.0051449716906106 0.995897277825391 -31.349026844254 34.0309968635267 -0.921190377407159 0.357460465728722 RAB27A other 1 1 1 0.0051449716906106 -0.921190377407159 1.10410532231564e-12 286.379737189377 78.945701860164 3.62755324788472 0.000319821648545553 -428.87073211531 129.874028212243 -3.30220551421136 0.00103786441371522 HDHD5 other 8.49609045521887e-09 1 1 3.62755324788472 -3.30220551421136 3.0937835244093e-14 571.879076021712 77.4127221481086 7.3874042941879 7.66003258649044e-13 188.004048408012 128.476907683494 1.46332949475375 0.144096117311035 UFD1 other 2.45924852355295e-10 1 7.37814338730759e-09 7.3874042941879 1.46332949475375 7.70031453131584e-77 1336.38630825406 57.6842293875174 23.1672733161838 6.18738629226652e-78 598.156776412183 292.808439059344 2.04282628715818 0.0416718736268991 LRP6 other 7.54707827214265e-73 1 6.09705045239943e-74 23.1672733161838 2.04282628715818 6.71316061734915e-23 306.547781361574 85.6817829878973 3.57774745893038 0.000385242915467096 -316.211672784653 99.4439482766619 -3.17979804970056 0.00157838381309273 PHRF1 other 5.8740155401805e-19 1 1 3.57774745893038 -3.17979804970056 0.000217522073389914 1000.52300650444 710.040114133455 1.40910772023844 0.159514484989351 -4395.33558178751 1482.03646598728 -2.96574050818613 0.00318501801790199 PFN2 other 1 1 1 1.40910772023844 -2.96574050818613 0.501316716807386 17.6050872300875 26.091771299368 0.674737143296743 0.500198773732823 62.0887137137139 53.9719704084613 1.15038812264634 0.250611727141111 PTPN3 other 1 1 1 0.674737143296743 1.15038812264634 0.0364778355555813 -1.89008781068606 11.0904891815963 -0.170424205798109 0.864755410406196 -31.5269385325198 15.6284597166987 -2.01727739675036 0.0442774731110635 DAPP1 other 1 1 1 -0.170424205798109 -2.01727739675036 0.00630225534743668 1366.37619730326 585.838694265728 2.3323420092895 0.0201349720527719 -1358.68042594238 1220.62104218352 -1.11310585266651 0.266273473897604 SLC44A1 other 1 1 1 2.3323420092895 -1.11310585266651 6.90342846214059e-17 32.3722374071746 27.094232157469 1.19480180205995 0.232814008617905 -154.445947514434 33.5347058018093 -4.60555546326283 5.40624846326016e-06 TMEM260 other 5.70982568103648e-13 0.0463423618270661 1 1.19480180205995 -4.60555546326283 0.167868236912165 139.666069124545 81.7832760990238 1.7077583069115 0.088389792000122 43.1070731513247 62.7782902874799 0.686655736464388 0.4926630542308 SMG6 essential 1 1 1 1.7077583069115 0.686655736464388 1.41356312516117e-18 2.17583619881592 134.87393644049 0.0161323696500544 0.987136169064242 -974.169695887112 166.490024934763 -5.85121959269828 9.59568209166852e-09 EXOC5 essential 1.1919164271359e-14 8.86065284344671e-05 1 0.0161323696500544 -5.85121959269828 0.000443351473203787 -1.72486671105624 32.9552449673125 -0.0523396719632063 0.958281904900406 -177.753587504451 54.6891619563547 -3.25025253900049 0.00124195090804153 CLTCL1 other 1 1 1 -0.0523396719632063 -3.25025253900049 0.58697477319224 -2.10529255280061 2.93558839477829 -0.717162036934545 0.473659908719151 4.91202398624317 8.58183297412587 0.572374689772321 0.567364530104907 FGF22 other 1 1 1 -0.717162036934545 0.572374689772321 0.00041039162778522 139.831052778554 35.4283893962235 3.94686451068135 9.23442640352939e-05 143.2578609327 103.570555354932 1.38319100869703 0.167317436568363 FSTL3 other 1 1 0.768581309565751 3.94686451068135 1.38319100869703 1.20377961235647e-14 4088.59158101469 712.638427041765 5.7372594935511 1.79738305904233e-08 -1713.38773860194 1172.36557529996 -1.46147905968968 0.144601049456491 DGCR2 other 9.61940288234055e-11 1 0.000166581461912043 5.7372594935511 -1.46147905968968 1.27494521237143e-06 149.444259909758 32.344141412525 4.62044294216099 5.05552757370518e-06 -144.790305560046 94.5541342878762 -1.53129534367289 0.126424975600932 RNF126 other 0.00765987083592754 1 0.0443976431522789 4.62044294216099 -1.53129534367289 0.589769320898157 -26.9575425261209 36.649413426385 -0.735551813953819 0.462397184434137 -18.6072720720044 28.1327384361767 -0.661409912661641 0.50869724596235 MNT other 1 1 1 -0.735551813953819 -0.661409912661641 0.00043342790681602 99.3506518283022 41.2385740168772 2.40916797432526 0.0164016221870096 -141.815035203268 81.9105954805214 -1.73133932638778 0.0840970329856484 ZXDC other 1 1 1 2.40916797432526 -1.73133932638778 0.118295459322606 45.310860756111 23.8351502949998 1.90101007106368 0.0579643822895586 6.92625907289453 28.1035077459448 0.24645532278418 0.805446578578791 FRMPD1 other 1 1 1 1.90101007106368 0.24645532278418 3.04409006983784e-08 384.771064357645 87.6489160839719 4.38991240905952 1.42522154580232e-05 -122.006862686942 103.162205138501 -1.1826701699827 0.237585898448862 GBA2 other 0.000202523312346312 1 0.123110637126404 4.38991240905952 -1.1826701699827 2.99851078767445e-07 -241.170109225135 288.578774002475 -0.835716729543894 0.403770976288451 -2974.33298205189 555.90661143058 -5.35041843520747 1.41895250936363e-07 NDST1 other 0.00187916671063558 0.00128273306846473 1 -0.835716729543894 -5.35041843520747 0.874683959216812 -5.16472907026998 10.4018406587962 -0.496520687028838 0.619776187702641 -7.52920447878121 24.1824729101556 -0.31134965008559 0.755682959596258 CNGB1 other 1 1 1 -0.496520687028838 -0.31134965008559 1.03674484285335e-15 -30.2900173350322 18.7657050318443 -1.61411560522942 0.107222499236715 -143.529066394555 24.2129552361354 -5.9277797771811 6.22873941552576e-09 TESK2 other 8.43080906208347e-12 5.76968132060151e-05 1 -1.61411560522942 -5.9277797771811 6.3975490772239e-07 187.453471336575 45.0315588522276 4.1627133529112 3.78779093713334e-05 -188.281922910714 104.690553121019 -1.79846143990725 0.0727923088766725 CFAP20 other 0.00393321317267725 1 0.32101528192205 4.1627133529112 -1.79846143990725 2.81435295809549e-11 265.442375440361 58.1943547675855 4.56130799113548 6.60831514680296e-06 -478.431303472567 134.31086665038 -3.56211910029555 0.000408231254151878 CSNK2A2 other 2.09978874203504e-07 1 0.0577698910133515 4.56130799113548 -3.56211910029555 0.00218686129768745 44.4303925056362 99.3885930878395 0.447037141036585 0.655069718018465 -179.574274798409 115.252453506308 -1.55809502822063 0.119934604283605 PTPN21 other 1 1 1 0.447037141036585 -1.55809502822063 3.38235830375912e-40 91.4694055672389 19.7763106016819 4.62520069640591 4.93399668878143e-06 -96.4190217447603 25.5169162321302 -3.7786314328748 0.00017950762130427 EIF2B3 essential 3.15979912737177e-36 1 0.043340226914256 4.62520069640591 -3.7786314328748 0.601160947975514 -1349.01727916273 1494.69617795577 -0.902536113397784 0.367268204695269 -2277.49033478965 2879.23640469194 -0.791004980028143 0.429369189188289 CAMK2A other 1 1 1 -0.902536113397784 -0.791004980028143 0.00012319150604474 128.821258618103 51.0442062622037 2.5237194982791 0.0119655275538855 -204.049788294368 98.3295179434848 -2.07516311034542 0.0385559424164027 TCOF1 other 0.60351518811318 1 1 2.5237194982791 -2.07516311034542 2.33548788387957e-74 387.099631598623 146.068861794646 2.6501173956078 0.00833900909354063 -1833.17846580747 187.703436620485 -9.76635536787722 1.65926537817716e-20 CDC42 essential 2.28620908952971e-70 1.62856896868089e-16 1 2.6501173956078 -9.76635536787722 0.762793306856728 -19.2263091676095 63.0520678880227 -0.304927495823839 0.76056721319652 -49.8967273893477 81.0589262639784 -0.615561168758303 0.538506104885909 EPHA8 other 1 1 1 -0.304927495823839 -0.615561168758303 0.00272906345009795 92.8108665749666 30.3162648724381 3.06142154930653 0.00233877254079777 -17.4482594434452 66.9741332430704 -0.260522362866868 0.794583581474293 RAD18 other 1 1 1 3.06142154930653 -0.260522362866868 0.165417554678117 -268.571446789524 356.170162910741 -0.754053749462531 0.451223988401203 -1064.98501226606 574.372553140048 -1.8541711410893 0.0643897659708018 ATP2B1 other 1 1 1 -0.754053749462531 -1.8541711410893 0.00284257743951194 528.760432045559 441.412501909553 1.19788277350129 0.231613438789372 -1368.75803684961 701.194752304925 -1.95203690893337 0.051573557887289 WDR1 essential 1 1 1 1.19788277350129 -1.95203690893337 0.000175345779101692 60.4398687664046 25.8640216874586 2.33683181590092 0.0198988557285194 -21.6807804024492 34.1586041274837 -0.634709203032247 0.525950238134504 ARHGAP10 other 0.842010431246323 1 1 2.33683181590092 -0.634709203032247 3.01551321690761e-09 -620.613086888335 261.452488343097 -2.37371268034719 0.0180406505301574 -1839.88376378687 334.037989002475 -5.50800754513356 6.19858454940041e-08 RPS6KA2 other 2.10754218729673e-05 0.000564753038295871 1 -2.37371268034719 -5.50800754513356 2.42744714635445e-06 160.984168398265 360.339875333658 0.446756463600374 0.65527172074678 -994.055587670088 415.5006693061 -2.39242836679468 0.0171578324549851 VASH1 other 0.0142830990091496 1 1 0.446756463600374 -2.39242836679468 0.245813082620805 139.279333955805 92.8540081823608 1.49998192519882 0.134341177564487 -20.2014260249547 206.92711911449 -0.097625802318243 0.922274194851715 LMCD1 other 1 1 1 1.49998192519882 -0.097625802318243 5.50166965823069e-13 -83.417882129708 259.624550989201 -0.321301979384752 0.748135169507555 -1370.23045253763 301.064393431284 -4.5512869752576 6.9200686176967e-06 SEL1L other 4.26159331726549e-09 0.0590351053775705 1 -0.321301979384752 -4.5512869752576 0.134411742154328 48.3886109601145 24.1305559964768 2.00528371443988 0.0455488582928266 42.913552354421 37.0800516017414 1.15732180783712 0.247773091612975 TRIP13 other 1 1 1 2.00528371443988 1.15732180783712 0.0078788941019441 99.3808720790225 105.101403921587 0.945571308953853 0.344889807008198 -509.733558178743 219.373680638238 -2.32358574964755 0.020605651678193 HLTF other 1 1 1 0.945571308953853 -2.32358574964755 0.0562609050769129 0.660790932434835 29.8015833845969 0.0221730142290482 0.982320041303871 84.6502529308229 46.3713896201658 1.82548449861443 0.0686087485905522 CDH19 other 1 1 1 0.0221730142290482 1.82548449861443 1.53985629341456e-24 34.7829123810103 42.7760219837978 0.813140417642971 0.416582378787656 -347.374716336092 55.2445209927593 -6.28794874303682 7.83724422227329e-10 PDCD2 essential 1.35938513582638e-20 7.35055135607011e-06 1 0.813140417642971 -6.28794874303682 0.267535493071426 47.2864792503306 60.7380881301038 0.778530913733089 0.436677426723776 -65.4059683710952 96.7200689161806 -0.67623988593078 0.499246088880099 SLC6A15 other 1 1 1 0.778530913733089 -0.67623988593078 1.1359529486403e-37 -143.797683299137 188.792195256591 -0.761671758219135 0.446667728781681 -1771.16604069934 215.305377506627 -8.22629727696805 2.24639442208897e-15 RDH11 other 1.05439152692792e-33 2.18416929659711e-11 1 -0.761671758219135 -8.22629727696805 0.356697093671005 560.665516039609 970.863883257441 0.577491372074183 0.563904973079818 -222.949884088835 1107.08631186811 -0.20138437418906 0.84049173581882 ACTN1 other 1 1 1 0.577491372074183 -0.20138437418906 1.46547307975479e-21 -68.3327629146912 100.191405658007 -0.682022200067123 0.495586230398813 -687.438911688224 114.249315154915 -6.0170068481907 3.76201204633788e-09 ZFYVE26 other 1.27012551822348e-17 3.49679019707106e-05 1 -0.682022200067123 -6.0170068481907 4.45986293135066e-14 57.3046399089199 596.558716510572 0.0960586750690858 0.923517906198655 -3785.38480435161 466.006953089335 -8.12302215504912 4.6750003360245e-15 EPN2 other 3.53354940050913e-10 4.53755532614538e-11 1 0.0960586750690858 -8.12302215504912 6.60417060783555e-06 454.601939893027 95.2511663586256 4.77266533599628 2.52147787893099e-06 225.928028695134 164.197572141976 1.37595231006084 0.169576691369032 LNX1 other 0.0373597931285257 1 0.02236046583036 4.77266533599628 1.37595231006084 6.02423259101746e-09 852.931739254191 146.459666927612 5.82366297252166 1.11535828008298e-08 250.882577636806 114.408223778264 2.19287188762798 0.0288418112720252 ALDH3A2 other 4.15611806454295e-05 1 0.000103728320047717 5.82366297252166 2.19287188762798 0.119679876950439 348.826430503265 284.983149736702 1.22402475664104 0.221606948136135 -347.697104754087 495.949734743178 -0.701073274964322 0.483633003275453 TFRC essential 1 1 1 1.22402475664104 -0.701073274964322 0.436909679397223 -321.080167054761 373.3835191901 -0.859920565726122 0.390303251066053 279.703228304712 277.127721973538 1.00929357161684 0.313391096481452 SREBF1 other 1 1 1 -0.859920565726122 1.00929357161684 4.65574328318138e-13 40.4023053071777 22.690715118717 1.78056553510078 0.0756796734098683 -99.7850024544381 29.292824987871 -3.40646566166817 0.000719115587224544 UBE2D1 other 3.61239121342043e-09 1 1 1.78056553510078 -3.40646566166817 3.3870980200607e-15 -53.2318832731214 116.327146547177 -0.457604994647856 0.647463680754428 -639.312386371547 132.524814328258 -4.82409569567854 1.94604911779702e-06 MPP5 other 2.73304939238698e-11 0.0169948469457214 1 -0.457604994647856 -4.82409569567854 0.0248977922853339 78.9574581211925 29.7295467300291 2.65585812115458 0.00819997363588174 94.2632267132022 38.3743707572803 2.45641100695622 0.0144212363350534 RHOBTB1 other 1 1 1 2.65585812115458 2.45641100695622 0.00322378977058635 60.399223006097 22.4769484153658 2.68716294978933 0.00748239965447184 127.881939683454 40.0827923761942 3.19044487926956 0.00152336752831355 HMMR other 1 1 1 2.68716294978933 3.19044487926956 2.65247378625687e-05 175.90350046169 37.9523761954811 4.63484814641552 4.72551844683166e-06 81.6428401827574 68.0771255499519 1.19926979177245 0.231074398485752 CHFR other 0.141270753856041 1 0.0415420326660971 4.63484814641552 1.19926979177245 0.297551663718094 -40.4911664441549 37.3204394771209 -1.08495952918716 0.278536386389365 -96.4586903265127 62.7423720372546 -1.53737716943883 0.124923030829925 TRHDE other 1 1 1 -1.08495952918716 -1.53737716943883 1.28067305779839e-06 208.253284648084 41.594809608696 5.00671325598629 8.03921968315446e-07 16.1214132999237 95.9996025218119 0.167932083846501 0.866714220962811 NFATC3 other 0.00769172238513714 1 0.00723208202696575 5.00671325598629 0.167932083846501 6.13145845514407e-08 47.2018086625417 28.637384088812 1.64825839246199 0.100023347757228 -261.307405997143 59.5621953227354 -4.38713523874093 1.44348754237048e-05 TRNT1 essential 0.000399832405859945 0.12109416992946 1 1.64825839246199 -4.38713523874093 0.0055317594480058 817.628987132446 297.225382240894 2.75087201829141 0.00619006777929429 359.701984504553 222.176383744807 1.61899288503007 0.106168584621474 ACADVL other 1 1 1 2.75087201829141 1.61899288503007 0.15248132625813 -5.37790202989969 64.6637913393804 -0.0831671313807506 0.933756729269165 -204.169244560591 118.659993581522 -1.72062409914359 0.0860269219593529 STK10 other 1 1 1 -0.0831671313807506 -1.72062409914359 1.35164033674116e-09 217.94663911511 153.429883040676 1.42049667767347 0.156176211477748 -1353.740245533 281.548430113976 -4.8081967460624 2.09889618453391e-06 FBXW11 other 9.56904586328972e-06 0.0183065725215048 1 1.42049667767347 -4.8081967460624 0.465088444322672 5.15324407593683 9.71017467125709 0.530705600095008 0.595891779306067 -8.25383988038601 7.25836897819788 -1.13714801564625 0.256098124488068 ACAP1 other 1 1 1 0.530705600095008 -1.13714801564625 0.163620644022297 198.819233044705 574.666845375546 0.345973035759138 0.729529098535373 -1216.98639555916 912.758255294704 -1.33330636945729 0.183124299681761 CRMP1 other 1 1 1 0.345973035759138 -1.33330636945729 0.39682181027882 32.6726725111606 50.2442922215267 0.650276301377816 0.515854691720987 -48.0973060036737 79.8043124911231 -0.602690562731479 0.547026468336282 EVC other 1 1 1 0.650276301377816 -0.602690562731479 2.05088985402027e-05 144.10507834423 33.2223561406065 4.33759356905141 1.78974944173337e-05 -49.7712672096915 24.4233169152928 -2.03785863248275 0.0421644230137806 DERL2 other 0.110399400841911 1 0.153864759505818 4.33759356905141 -2.03785863248275 0.162438287364657 -64.381966566824 66.5350019409702 -0.9676405604368 0.333757905892356 -251.96811205416 132.15204118452 -1.90665319881321 0.0572195828527268 SIDT1 other 1 1 1 -0.9676405604368 -1.90665319881321 1.02984833046182e-08 -265.317658263643 270.970999898448 -0.979136728148309 0.328052923791053 -1626.2518824965 328.626460214922 -4.94863341628951 1.06782397068301e-06 MRVI1 other 7.0235656137496e-05 0.00940432570980528 1 -0.979136728148309 -4.94863341628951 1.40011944150225e-20 245.863666701583 33.6958874658208 7.29654819007138 1.40191699719635e-12 122.796174969696 42.0005614011474 2.92367937173194 0.00363899035583807 PVR other 1.20284261219458e-16 1 1.34906472640205e-08 7.29654819007138 2.92367937173194 2.99403147985611e-55 301.031087262833 43.9843079663689 6.84405646425099 2.62799467489117e-11 -107.041789276045 54.1979478757881 -1.97501553972792 0.0488982249555433 XRCC1 other 2.88205470250949e-51 1 2.5089465161186e-07 6.84405646425099 -1.97501553972792 0.0126618236622427 155.603878132184 165.812138369171 0.938434783258997 0.348538207911579 -704.234134653878 305.32300772262 -2.30652167324927 0.0215474129218065 SCARB1 other 1 1 1 0.938434783258997 -2.30652167324927 0.0204482416964268 408.966910244039 146.438036717944 2.79276422581214 0.0054559679823653 300.575013294991 299.195274130907 1.00461150052617 0.315641168623654 MCM2 essential 1 1 1 2.79276422581214 1.00461150052617 7.27921498685413e-05 -6.60921536775355 5.4667532872121 -1.20898365456036 0.227321343232321 -31.6790180843153 7.99015906824323 -3.96475437018809 8.57901696647829e-05 MOV10L1 other 0.367236396086791 0.686492937657593 1 -1.20898365456036 -3.96475437018809 0.025298436494703 -48.2511889850079 43.474209057264 -1.10988077831276 0.267659369386957 -164.662313578894 63.5415259265792 -2.59141264201237 0.00987745120950617 PANX2 other 1 1 1 -1.10988077831276 -2.59141264201237 1.47945649129877e-08 125.639145216126 45.5924386320411 2.75570136158128 0.00610154080757136 -148.648108084239 66.6455630818653 -2.23042767155623 0.0262260574386261 SELENOO other 0.000100218382720578 1 1 2.75570136158128 -2.23042767155623 0.926071250272917 -8.91917195889766 36.9119769542564 -0.241633548101497 0.80917825005166 -28.6191910381859 74.3208557061677 -0.385076177692757 0.700369622136383 TP63 other 1 1 1 -0.241633548101497 -0.385076177692757 0.0216569129459543 8.64021024967181 32.8255055824622 0.263216364724875 0.792507594049606 -90.2228646517744 46.1437554047748 -1.95525621745209 0.0511883662454481 ALPK1 other 1 1 1 0.263216364724875 -1.95525621745209 0.000175902897256623 340.95325903455 136.60923852384 2.49582870616067 0.0129348291372356 -406.307202497379 259.326236885504 -1.56678015837159 0.117891547226026 PDE8A other 0.844333906831791 1 1 2.49582870616067 -1.56678015837159 0.000264473053400488 98.0645256334703 30.8963509653315 3.17398406509259 0.00160960899070189 -113.066973391958 67.1205196476903 -1.68453662137058 0.0927903812392656 NLE1 essential 1 1 1 3.17398406509259 -1.68453662137058 2.25929484204295e-13 82.3944219293489 149.917575469129 0.549598148659466 0.582879687106597 -1355.63728864556 230.580230417841 -5.87924336006156 8.26785765436683e-09 SDHA ts 1.76563891905656e-09 7.64446118722757e-05 1 0.549598148659466 -5.87924336006156 7.00806177429416e-07 532.552612756435 112.263787678784 4.7437613122426 2.84355484344802e-06 -385.880652506678 252.17763039373 -1.53019382371146 0.126690637192774 SMARCE1 other 0.00429243783675517 1 0.0251967394677929 4.7437613122426 -1.53019382371146 0.00834813828278466 4.9460813199764 3.23535093920832 1.52876192194059 0.127045309585337 -15.6240499826239 7.0286111303557 -2.2229213841616 0.0267308285250108 FNDC8 other 1 1 1 1.52876192194059 -2.2229213841616 0.00353280240305842 80.2025537634422 23.7391345783417 3.37849526480273 0.000794151533868633 49.6432795698933 53.7096601400185 0.924289586649324 0.355845648651404 GSDMB other 1 1 1 3.37849526480273 0.924289586649324 0.634621417425235 -67.0246482175415 86.3706451492803 -0.776011897348899 0.43816077489131 -134.007339419615 193.440700518021 -0.692756690090308 0.488829389664282 ADAM11 other 1 1 1 -0.776011897348899 -0.692756690090308 0.332476470662352 11.346511243121 38.8551517081473 0.29202076801419 0.770409009350615 -98.9507309496752 81.9173156673578 -1.20793424617922 0.227724362142096 PPP2R3A other 1 1 1 0.29202076801419 -1.20793424617922 7.22663079744114e-09 36.9053167546406 281.961817107205 0.130887639799146 0.895924562815387 -1390.29019105194 354.29374219934 -3.92411726614609 0.000101118108242293 FERMT2 other 4.96770691667746e-05 0.8042934329592 1 0.130887639799146 -3.92411726614609 0.324566098392037 104.722487397945 235.765456084714 0.444180793645686 0.657131749591366 -733.370132042656 614.371414141341 -1.19369182087944 0.233246136948751 ST6GAL1 other 1 1 1 0.444180793645686 -1.19369182087944 4.27368034657931e-09 120.519361073593 244.353166936907 0.493217921356883 0.62210751066024 -1090.07884997639 294.656152590608 -3.6994946156476 0.000243712940498856 FRY other 2.96379732035275e-05 1 1 0.493217921356883 -3.6994946156476 0.57245271302721 -258.156205824777 399.075534756426 -0.646885572633115 0.518046405889001 -865.759388001733 934.426436522235 -0.926514227512581 0.354691373319851 NSF essential 1 1 1 -0.646885572633115 -0.926514227512581 0.222253005595931 -534.853708384874 415.353814707153 -1.28770626257995 0.19852818015865 -1118.27200672578 659.717236678838 -1.69507774627113 0.0907714036998026 PPP2R2C other 1 1 1 -1.28770626257995 -1.69507774627113 4.70688096225645e-21 293.084056388594 44.5232348619603 6.58272152275706 1.32342373876932e-10 121.521582706273 54.3269664596838 2.23685566534356 0.0257982646780234 TEAD2 other 4.06674515138958e-17 1 1.25778192132636e-06 6.58272152275706 2.23685566534356 0.00815521311250603 -5.54292179848646 12.2005682176542 -0.454316692436164 0.649825958832777 -70.9215017064849 23.9987343983134 -2.95521840982869 0.00329305884350197 CDHR2 other 1 1 1 -0.454316692436164 -2.95521840982869 0.0973001596795842 -434.155290102396 443.59359114086 -0.978723089722306 0.32825708478342 -1888.5895904437 872.556473163211 -2.16443250211318 0.0309708117789162 SNCB other 1 1 1 -0.978723089722306 -2.16443250211318 6.65631371161259e-29 460.007465834492 68.7715315608308 6.6889228056176 6.8961714792743e-11 -282.487627595989 86.2261894257789 -3.27612329243827 0.00113627309741644 TSG101 essential 5.99800428553411e-25 1 6.56929295115669e-07 6.6889228056176 -3.27612329243827 0.0229833674240822 114.099897378133 46.4444189969689 2.4566977010861 0.0144090045341912 37.3523584025544 33.8470005471822 1.10356480038714 0.270387895624888 NCBP3 other 1 1 1 2.4566977010861 1.10356480038714 0.826939339863536 12.3560149544596 22.4883973849046 0.549439550670412 0.582983854754953 -5.12619552748332 16.3887247387418 -0.312787944712095 0.754590647429165 ATP2A3 other 1 1 1 0.549439550670412 -0.312787944712095 0.162150893761802 -356.047993382907 197.744072306546 -1.8005495144803 0.0724633196698143 -524.547374659689 327.933303975828 -1.59955505677567 0.110420017516524 CA12 other 1 1 1 -1.8005495144803 -1.59955505677567 0.108060753511919 -890.443126981944 512.589545263724 -1.73714648534983 0.0830675209296162 -1925.28294695791 1047.29872749669 -1.83833217439289 0.0666935308599292 MGLL other 1 1 1 -1.73714648534983 -1.83833217439289 0.0684237333432486 112.634366925065 132.521393171266 0.849933465304736 0.395826420579293 -281.691079118987 219.757338636949 -1.28182786006686 0.200581137058773 NTN4 other 1 1 1 0.849933465304736 -1.28182786006686 0.448846753917792 -80.2541031715552 178.548145201148 -0.449481584259209 0.653306629213323 -372.152025440729 302.481683903063 -1.2303291248537 0.219234238022043 NUAK1 other 1 1 1 -0.449481584259209 -1.2303291248537 9.28200478167846e-05 -46.680831193093 140.682449032959 -0.331817021341138 0.740187241999217 -903.73257062807 241.776262145018 -3.73788792419171 0.000210342645907514 DPP8 other 0.461965377984137 1 1 -0.331817021341138 -3.73788792419171 4.98460727366284e-05 -16.2640672425878 20.3287822921471 -0.800051228295682 0.424117805552834 -142.535780994631 34.9369593033147 -4.07979926808077 5.36233185360629e-05 SLC24A1 other 0.256308506011743 0.435528593149903 1 -0.800051228295682 -4.07979926808077 8.59144384664118e-10 369.747650882232 200.725512554597 1.84205608034834 0.0661427554430201 -1195.05489677033 323.199486105808 -3.69757672318544 0.000245305851050897 ZNF532 other 6.13085432896315e-06 1 1 1.84205608034834 -3.69757672318544 0.181032281602332 -7.71726980688401 21.8404573252601 -0.35334744561225 0.723999154618155 -27.8973546075654 15.5247499938065 -1.79695999089808 0.0730355194023894 SCARF1 other 1 1 1 -0.35334744561225 -1.79695999089808 0.00029589915156082 101.458960200305 109.429663583505 0.927161401011543 0.35435334712664 -430.99190011718 176.198882667197 -2.44605353673686 0.0148354218084627 LMAN1 other 1 1 1 0.927161401011543 -2.44605353673686 1.3269681161052e-07 -631.942563623643 337.709540268839 -1.87126061976388 0.0619799811443941 -3194.44540042029 580.386188171797 -5.50399969110691 6.35423488399491e-08 HACD3 other 0.000848596110249277 0.000578870797931936 1 -1.87126061976388 -5.50399969110691 0.354604307212767 -132.927338847694 119.447015675344 -1.11285609017632 0.266380625757371 -227.009856119671 157.462822879713 -1.44167271974469 0.150109306441841 IPCEF1 other 1 1 1 -1.11285609017632 -1.44167271974469 0.00519479304850028 -47.1411638079952 110.241258412798 -0.427618157545654 0.669139300651912 -257.320661375479 80.3398129291607 -3.20290341729287 0.00145974243564501 ZZEF1 other 1 1 1 -0.427618157545654 -3.20290341729287 8.02551533128355e-22 2377.27448066951 1312.2661774763 1.81157948095667 0.0707375593281599 -6466.93174388904 1678.02760894211 -3.85388876167898 0.000133693898140517 ENO1 essential 6.96935751368664e-18 1 1 1.81157948095667 -3.85388876167898 0.058334004975337 -2.03556825626312 2.64829932545228 -0.768632245116585 0.442528748365696 -8.94159306029321 4.00445957009543 -2.23290881173264 0.0260629904577105 SLC12A1 other 1 1 1 -0.768632245116585 -2.23290881173264 2.62464113935092e-07 99.031859042153 43.8808457419668 2.25683569602308 0.0245104000808764 -105.434959963739 59.8677900745697 -1.76112998045213 0.0789141309999222 TUBE1 essential 0.00165089927665173 1 1 2.25683569602308 -1.76112998045213 6.88686944745311e-51 236.900052186638 221.062127541622 1.07164467663975 0.284469779698309 -2361.46259344932 282.477141903944 -8.35983604737948 8.42408095569452e-16 ARHGEF10L other 6.58384719176517e-47 8.20168521846419e-12 1 1.07164467663975 -8.35983604737948 0.018491349702151 -111.913009228 64.2759181155638 -1.74113435496616 0.0823621766368433 -304.816452847175 107.515819598457 -2.83508467856715 0.00479342538283165 WSCD2 other 1 1 1 -1.74113435496616 -2.83508467856715 8.43473463897433e-12 101.411702471851 38.9956663383506 2.60058903961122 0.00962184711547501 -295.080804322505 67.7925138841596 -4.35270485509247 1.67628444750093e-05 ACTR6 essential 6.36316381164224e-08 0.140221194033453 1 2.60058903961122 -4.35270485509247 1.5782857994454e-09 71.9943217137657 16.0347587650923 4.48989116509178 9.12906592877082e-06 -39.351197022587 28.3098232436492 -1.39001917051583 0.165230678898568 TIPIN other 1.11490108872823e-05 1 0.0794228735803061 4.48989116509178 -1.39001917051583 1.54500588530065e-26 -1.72002035101056 179.273238622819 -0.00959440663996365 0.992349266884352 -1439.84251522385 230.28041791483 -6.2525616735522 9.61699038171168e-10 EIF4G3 other 1.37799074909965e-22 9.00823489054933e-06 1 -0.00959440663996365 -6.2525616735522 6.4276312863179e-06 68.8755241361463 15.0016488434989 4.59119693139558 5.76995490074499e-06 24.3261776886264 26.0798079120913 0.932759082069318 0.351459429647191 NUP37 other 0.0364189588682772 1 0.0505563448403276 4.59119693139558 0.932759082069318 0.005549865888122 128.953375424964 40.5848987171304 3.17737334577934 0.00159158292778295 154.502414872377 59.3257019974968 2.60430824533515 0.0095196585834029 GTSE1 other 1 1 1 3.17737334577934 2.60430824533515 0.877423499295153 -15.1165614375906 41.9629312633324 -0.360236069847666 0.718844646810191 -31.3361345362313 61.3400657328515 -0.510859161330321 0.609707656240497 TTC38 other 1 1 1 -0.360236069847666 -0.510859161330321 0.0092723982613369 175.855755220982 69.0846333535331 2.54551188425737 0.0112542917813389 42.1570133093946 100.985699126757 0.417455280043953 0.676550445118384 GRAMD4 other 1 1 1 2.54551188425737 0.417455280043953 0.0505489877756854 -44.7411364740149 57.6746019211045 -0.775751110258519 0.438315565218608 102.086313597364 84.3068814891853 1.21088945284329 0.226592231397648 CELSR1 other 1 1 1 -0.775751110258519 1.21088945284329 5.47295643060684e-27 86.220668417001 27.0796691632194 3.18396313844591 0.00155708831914787 -245.734165070969 40.3624031779834 -6.08819459999375 2.51065209587372e-09 TIMM21 other 4.8944649358917e-23 2.3381702968872e-05 1 3.18396313844591 -6.08819459999375 0.00604343899523882 133.818036746315 63.2292353333833 2.11639498786826 0.0348759757393752 -181.109715632996 134.354868475816 -1.34799518385592 0.178358258148557 VPS9D1 other 1 1 1 2.11639498786826 -1.34799518385592 4.52755128727792e-15 97.4926885332851 29.4868124456688 3.30631494037957 0.00102595628585125 -232.540537841873 53.8026334677483 -4.32210326621407 1.92880748464169e-05 ZNF37A other 3.64467878625872e-11 0.160862544219117 1 3.30631494037957 -4.32210326621407 1.01264036360396e-31 345.568714400399 92.1130410250388 3.75157209614287 0.00019958411171926 -519.34905768569 106.989262051242 -4.85421665434937 1.68912356653219e-06 MARK3 other 9.22110315097762e-28 0.0147832094542897 1 3.75157209614287 -4.85421665434937 2.18791132860339e-10 1006.64005759026 326.24231745742 3.08555942538522 0.00216076391586297 -1951.87017924162 567.160120920453 -3.44147994057463 0.000634206593027254 SLC25A3 essential 1.59236186495754e-06 1 1 3.08555942538522 -3.44147994057463 0.000144009604203311 206.438462687203 166.367613772767 1.24085726786445 0.215327262780247 -661.740268236837 263.071320565997 -2.51544055358488 0.0122476898330647 FRYL other 0.700030686032295 1 1 1.24085726786445 -2.51544055358488 1.21045481714935e-07 18162.9638954126 3211.63843603316 5.65535761797846 2.82130742932419e-08 533.985791451405 12775.5400902872 0.0417975120955847 0.966679295958006 ACTB essential 0.000775538401347591 1 0.000260491314949502 5.65535761797846 0.0417975120955847 0.02261577792776 9.81046880308 4.04630330579749 2.42455101895691 0.0157319369993711 2.16670818706826 7.26262453453814 0.29833680328155 0.765587917032568 MOCOS other 1 1 1 2.42455101895691 0.29833680328155 1.85652974513537e-15 236.793314950082 40.5530483813601 5.83910025020271 1.02658352458935e-08 83.7168544154952 53.3196216545498 1.57009468217694 0.117118491627123 WDR62 other 1.50471735843222e-11 1 9.55338627982853e-05 5.83910025020271 1.57009468217694 2.27945751095863e-05 51.3644186946249 116.161366132064 0.442181599657053 0.658578064404231 -757.336573029991 206.404191965831 -3.66919182123668 0.00027357823020331 DLG1 other 0.121996565986506 1 1 0.442181599657053 -3.66919182123668 1.4656849763953e-08 -454.151385633533 329.059340966679 -1.38015041390215 0.16824757851782 -4024.1335998897 672.318490007434 -5.98545727910176 4.50899956299237e-09 RAB7A other 9.93001571507817e-05 4.18525339436952e-05 1 -1.38015041390215 -5.98545727910176 1.63279550833579e-12 45.4470120793726 105.081924582524 0.432491242046881 0.665597760858381 -494.323390398102 126.739162542104 -3.90032078864244 0.000111181542900787 SEC31B other 1.25170103669022e-08 0.879890730516826 1 0.432491242046881 -3.90032078864244 2.69226825769076e-10 75.7863761531415 84.4984813783624 0.896896310050706 0.37026807251885 -705.869961181679 141.35140299449 -4.99372447834279 8.57515574367566e-07 SART3 essential 1.95485598190926e-06 0.00758215270855802 1 0.896896310050706 -4.99372447834279 4.75811974157603e-05 96.5428571428586 84.5258241975804 1.1421699588186 0.25400737142587 -368.067669172932 133.02003353917 -2.76700929461538 0.00589688524394482 EXOSC7 essential 0.245471397467907 1 1 1.1421699588186 -2.76700929461538 1.07529364382075e-06 50.5319438383942 42.1028376797854 1.20020280397052 0.230709329169491 -383.817567186015 90.3751998449809 -4.24693464406575 2.64834371684291e-05 MKRN2 other 0.00650122537054024 0.219521210689109 1 1.20020280397052 -4.24693464406575 0.00793083117482047 134.201074734584 46.8560246112715 2.86411567878298 0.00438365024401033 50.1086109513091 76.2831314629891 0.656876690695645 0.511606774786158 RBMS2 other 1 1 1 2.86411567878298 0.656876690695645 1.48730483872928e-05 -20.2009505255981 165.927137444541 -0.121745911107217 0.903156342843487 -1065.1106571309 270.134774428015 -3.94288613669296 9.37714840462392e-05 BAZ2A other 0.0813394260893949 0.748296442688989 1 -0.121745911107217 -3.94288613669296 1.10255636728346e-10 -114.975866380415 153.243928543364 -0.750280076172019 0.453489799723764 -1406.70994833565 238.538180104557 -5.89721086879699 7.40822671953013e-09 PTPN23 essential 8.10268674316616e-07 6.85557300625318e-05 1 -0.750280076172019 -5.89721086879699 5.42604113299489e-06 66.5668050469313 51.09624779639 1.30277286332626 0.193336834861221 -302.0986085599 89.2958141728134 -3.38312172141968 0.000781079810777459 MLH1 ts 0.0309989729927998 1 1 1.30277286332626 -3.38312172141968 3.83982570613434e-05 202.910533423364 68.5375473211681 2.96057477038858 0.0032374501298201 -128.996838745317 114.644345651426 -1.12519146070693 0.26112410658163 UNG other 0.200515698374335 1 1 2.96057477038858 -1.12519146070693 0.0414891719333004 115.496638009702 101.07184259804 1.14271823923334 0.253782694946925 -402.813337495796 214.033491053808 -1.88201078024059 0.0605003696712949 SLC46A1 other 1 1 1 1.14271823923334 -1.88201078024059 3.33233583709526e-08 415.405624129482 69.4026678736557 5.98544172517558 4.50939773423222e-09 239.870835534637 146.969669411514 1.63211114575621 0.103378068027479 SPAG5 other 0.000220933865999416 1 4.22034533946794e-05 5.98544172517558 1.63211114575621 2.94718619598747e-06 214.329338284944 74.9944764582598 2.85793498944199 0.00446737536672478 -228.280676447114 125.445000836395 -1.8197670287781 0.0694769550499946 ANKRD13A other 0.0172174617569588 1 1 2.85793498944199 -1.8197670287781 0.284505657588021 91.6418523520143 74.9081104201511 1.22339025558121 0.221840091519577 -15.0632455548065 125.300534360537 -0.120216929893242 0.904366430747586 ACACB other 1 1 1 1.22339025558121 -0.120216929893242 0.495310945344088 320.262571442291 269.961405764397 1.18632724753921 0.236139140481124 180.571658421783 571.680308187712 0.315861252933854 0.752258967376654 TRAF4 other 1 1 1 1.18632724753921 0.315861252933854 1.72919501265459e-60 84.2437793349363 13.1678485611167 6.39768743875892 4.06571863007809e-10 -66.8560222877772 16.853139488707 -3.96697732980709 8.50513880223285e-05 GPATCH1 other 1.6745524502547e-56 0.680666258342695 3.8477961115059e-06 6.39768743875892 -3.96697732980709 5.45479089575843e-14 -60.4645097741154 194.740451442614 -0.310487673856158 0.756337822117039 -1097.78152141578 233.420450175834 -4.70302203850959 3.44086831756566e-06 NT5C2 other 4.31419411945535e-10 0.0297325431320849 1 -0.310487673856158 -4.70302203850959 6.94355011459509e-11 -42.5784553681893 233.99147569758 -0.181965839743749 0.855694103531585 1082.59086633223 300.694731423991 3.60029875217779 0.000354375591357605 RAP1GAP other 5.13336659972015e-07 1 1 -0.181965839743749 3.60029875217779 8.96417251418072e-07 11.2650595238121 97.1647702351411 0.11593769528349 0.907755299813588 -573.179007936507 149.86151491292 -3.82472450161446 0.000150014858589627 DGKD other 0.00544842405411904 1 1 0.11593769528349 -3.82472450161446 0.696152154280512 -2.33584559910145 21.656063531976 -0.107861042966211 0.914155310371431 -35.6889026817207 44.1949491191423 -0.807533516681043 0.419797492385526 RARB og 1 1 1 -0.107861042966211 -0.807533516681043 2.51871732073685e-28 798.158834587485 238.015754649803 3.35338656788425 0.000867649956258556 -1331.00483473284 300.739090046998 -4.42577928437849 1.21447164032877e-05 TM9SF3 other 2.26583810173487e-24 0.102440682861732 1 3.35338656788425 -4.42577928437849 0.236239946465435 79.7779235584434 51.507894423734 1.5488484716953 0.122140365867251 55.4720494774427 61.9577628146755 0.895320407926405 0.371107589174682 NFKB2 other 1 1 1 1.5488484716953 0.895320407926405 5.09818935037532e-32 115.921323404263 83.9803556898994 1.38033856194068 0.168186479428336 -625.109241124463 107.845269435618 -5.7963529081602 1.29772709001478e-08 USP33 other 4.64903886860726e-28 0.000119637460428462 1 1.38033856194068 -5.7963529081602 2.13250222900588e-24 220.833480992061 56.6014460344296 3.90155192956965 0.000110709339886917 -208.005520090196 77.3060378306183 -2.69067625152317 0.00740536330381547 SNRPA other 1.88086696598318e-20 1 0.917984259948129 3.90155192956965 -2.69067625152317 1.80186007302714e-34 122.12800347045 24.9341195045923 4.89802751799425 1.3675522657332e-06 -102.560457282842 33.6257405888111 -3.05005794629155 0.00242780643291804 EXOSC5 essential 1.65681033714846e-30 1 0.0122149768375289 4.89802751799425 -3.05005794629155 7.59016960092742e-05 80.4704945260348 76.4786877953394 1.05219502119829 0.29329287588021 607.38987872259 148.449611602397 4.09155586307229 5.10513538467311e-05 APBB1IP other 0.381785530926649 0.415506968958544 1 1.05219502119829 4.09155586307229 5.00011959528915e-09 153.392339933696 30.4793316818285 5.03266743296563 7.07518456455915e-07 -165.190805683375 80.8936313622914 -2.04207430055339 0.0417426082549961 SIRT6 other 3.46058277189962e-05 1 0.00637049618192905 5.03266743296563 -2.04207430055339 0.293111904242215 127.416436776876 108.720121445942 1.17196738821001 0.241847227083781 -134.505537942108 218.766688048854 -0.614835554451832 0.538982599748712 ACTN2 other 1 1 1 1.17196738821001 -0.614835554451832 5.27642981241126e-89 311.940742681798 211.747247948854 1.47317495600767 0.141422122581774 -3384.95304400571 270.574422094785 -12.5102477085581 6.46566303873742e-31 CAPZB other 5.19042400646895e-85 6.36867809315635e-27 1 1.47317495600767 -12.5102477085581 0.0694467100993176 -214.950288906273 150.339100716824 -1.42976968653783 0.15349601923654 -660.563676040679 302.512420981941 -2.18359191300813 0.0295221847063805 GPR137B other 1 1 1 -1.42976968653783 -2.18359191300813 6.5674168683242e-07 215.263206307489 174.893188011114 1.23082670489036 0.219048225596037 -802.412971653845 245.852374437085 -3.26379996732221 0.00118541939667957 JADE1 other 0.00403173721546423 1 1 1.23082670489036 -3.26379996732221 3.34251697378175e-08 22.3063227934593 177.146492708965 0.125920205657735 0.899853131441439 1185.97078282742 260.179470380602 4.55827964094374 6.70771108560658e-06 FBLN1 other 0.000221575450191992 0.0572637295378234 1 0.125920205657735 4.55827964094374 0.0682997035417105 -39.7150539132369 17.8429435971394 -2.22581289331678 0.0265349449086839 -65.9408951176248 36.7795109753519 -1.79287036094133 0.0736835350718468 ITGA8 other 1 1 1 -2.22581289331678 -1.79287036094133 1.90021649363623e-16 83.7072731527969 35.681883344867 2.34593203345693 0.0194246478381806 -277.03621199549 55.9607302540391 -4.95054676266479 1.05793048651542e-06 PIAS2 other 1.56140789282089e-12 0.00931930965571433 1 2.34593203345693 -4.95054676266479 0.214185243777873 -23.2077172141816 253.775330519781 -0.0914498551401655 0.927176957530691 -762.398593190367 509.17971568852 -1.49730747258743 0.135033536879459 NEBL other 1 1 1 -0.0914498551401655 -1.49730747258743 5.93435421672768e-06 131.653486745916 102.071877005535 1.28981155836663 0.197798250984614 -538.038329066521 165.57902829289 -3.24943523714122 0.00124564837446147 UBE2K other 0.0337308693678801 1 1 1.28981155836663 -3.24943523714122 8.03937327494516e-15 92.602174801218 64.8556112907719 1.42782055335271 0.154059375821084 -626.03391055659 109.715285460251 -5.70598625278515 2.13890507756179e-08 PIK3C3 essential 6.44516555452353e-11 0.000196543987577152 1 1.42782055335271 -5.70598625278515 0.0162760744390055 53.4955819719052 40.2179563010445 1.33014173001416 0.18416534421755 -89.3066585375699 65.2407922692729 -1.36887759070994 0.171740742523717 N4BP2 other 1 1 1 1.33014173001416 -1.36887759070994 0.103902400303217 -352.30617046035 197.193912535799 -1.78659759791719 0.0746940592022296 -549.620336895515 259.02916497545 -2.12184730992592 0.0344113567206441 SYNJ2 other 1 1 1 -1.78659759791719 -2.12184730992592 0.02152842596574 527.074162647812 648.817074023451 0.812361732990955 0.417027418498415 -1704.34071480479 1063.69418846703 -1.60228450365141 0.109816910056371 ADCY2 other 1 1 1 0.812361732990955 -1.60228450365141 5.98255837141569e-29 200.063037877948 211.281738944316 0.946901700438365 0.344213365373006 -1655.40153874001 250.16572281133 -6.6172196579804 1.07596314345611e-10 PPP2R5C other 5.39207986015696e-25 1.01700036319472e-06 1 0.946901700438365 -6.6172196579804 1.449665858513e-51 526.862307613809 485.19534989042 1.08587666335384 0.278130824636143 -5212.23357105088 619.951719563398 -8.40748304516616 5.94249177670233e-16 GNB1 other 1.38776512635449e-47 5.78917548886340e-12 1 1.08587666335384 -8.40748304516616 0.62185203438359 -23.3146908210197 71.6182716546315 -0.325541098414819 0.744928111749958 -121.240853873764 126.824719820463 -0.955971785669198 0.339617449494086 EDN1 other 1 1 1 -0.325541098414819 -0.955971785669198 2.06951831735438e-11 160.234346709335 22.9396429399833 6.98504101081934 1.06679645574396e-11 114.85759783187 44.9877037647838 2.5530886935772 0.0110159810466807 MLLT10 og 1.54841360504454e-07 1 1.02167096566599e-07 6.98504101081934 2.5530886935772 1.79883680067103e-08 498.569096360216 88.4110960019536 5.63921406821152 3.06728938977247e-08 -368.784166127086 248.463681001893 -1.48425783857028 0.138459796744681 TNRC6C other 0.000121331542205261 1 0.000282988119100408 5.63921406821152 -1.48425783857028 0.00156880591571199 -471.87469803397 182.028940288933 -2.59230591182351 0.0098522334968301 -1240.56959155609 370.411900916811 -3.34916234733696 0.000880648584072621 BRINP1 other 1 1 1 -2.59230591182351 -3.34916234733696 9.15569480289176e-53 649.98077584752 116.460154119737 5.5811430163423 4.21031317204308e-08 -791.802441672724 154.686332673879 -5.11876148322722 4.6258734958603e-07 SDF4 other 8.78397359389436e-49 0.00412812950770574 0.000387811946276888 5.5811430163423 -5.11876148322722 0.0190838004362382 58.4592424411447 35.35386577735 1.65354597455641 0.0989362846903965 8.7523845145991 45.1733206715671 0.193751187304413 0.84646053006878 TP73 other 1 1 1 1.65354597455641 0.193751187304413 1.41925833603317e-05 240.550724637671 290.356033011826 0.828468146993432 0.407856634154367 -719.335699497202 334.927483285791 -2.1477356603889 0.0322827680382171 TOLLIP other 0.0777422047236192 1 1 0.828468146993432 -2.1477356603889 0.903425356358649 -4.95647584246855 12.4182123977296 -0.399129575475352 0.689994051875353 -9.4385708485587 24.0897326010177 -0.391808867490706 0.695391756290674 CLUL1 other 1 1 1 -0.399129575475352 -0.391808867490706 1.59234174985982e-14 242.036306912282 36.509973045269 6.62932033973784 1.00588708481578e-10 -41.4542058103669 70.8314923467066 -0.58525105764335 0.558683784294877 THOC1 essential 1.2700517796882e-10 1 9.57000972493734e-07 6.62932033973784 -0.58525105764335 0.413727074994246 605.263488080269 3169.07269486829 0.190990723898628 0.848621357844323 -7168.11985285731 6801.66660054441 -1.05387697954551 0.29252025060204 SLC1A3 other 1 1 1 0.190990723898628 -1.05387697954551 0.771775742479255 7.06937965729396 12.8145978369463 0.551666134766395 0.5814603912563 -5.92940988911055 27.9884637372263 -0.211851923877626 0.832321781994756 LXN other 1 1 1 0.551666134766395 -0.211851923877626 0.642885875816275 -4.83607983376028 10.7613866499213 -0.449391885180117 0.653371273157693 -18.5225522598484 19.8255257716586 -0.934277984512633 0.350675286393694 SP140 other 1 1 1 -0.449391885180117 -0.934277984512633 5.06987668485799e-36 33.4248372708791 51.2540258208662 0.652140719398308 0.514652472509955 -457.485225229011 65.8151629619547 -6.95106119380828 1.32207273529106e-11 MKNK1 other 4.68558003214575e-32 1.26059635310002e-07 1 0.652140719398308 -6.95106119380828 5.02039653653978e-50 272.008682271457 94.5935420918996 2.87555235015087 0.00423081901802414 -897.101156186399 114.883786503492 -7.80877078907156 4.33983106519892e-14 SAR1A other 4.79096441481991e-46 4.19922053868648e-10 1 2.87555235015087 -7.80877078907156 2.05660285101103e-32 -0.389529270817041 14.9547744535984 -0.0260471511640426 0.979231592853211 -136.800339555355 19.2947350351821 -7.09003462892407 5.40728051252916e-12 CDC14A other 1.87952934553898e-28 5.17044162608039e-08 1 -0.0260471511640426 -7.09003462892407 0.145474318454827 -32.4509757720233 114.71076077823 -0.282893911189035 0.777392113567107 -301.3143732328 175.160839552491 -1.72021539747475 0.0861012370606415 RAPGEF3 other 1 1 1 -0.282893911189035 -1.72021539747475 1.16797295048432e-06 44.4447848774021 28.9928359541379 1.53295748465955 0.126008284493617 -137.820582306274 44.2684258420507 -3.11329304543188 0.00197138788339262 SENP1 other 0.00703236513486607 1 1 1.53295748465955 -3.11329304543188 6.32806836488262e-46 272.342456690591 165.365513458138 1.64691204952799 0.100298297533205 -1241.95229227415 202.469278387131 -6.13402834329995 1.92714810530468e-09 CIC og 5.99394635521682e-42 1.79706560819662e-05 1 1.64691204952799 -6.13402834329995 0.40687738342158 80.295911460885 96.3540330558311 0.833342506943727 0.40510891813656 29.0260195674791 118.023057229664 0.245935160881289 0.805848423177146 LIPE other 1 1 1 0.833342506943727 0.245935160881289 7.8657204945027e-21 330.246566926982 94.0630539848572 3.51090627974025 0.000493222203035771 -155.027128540276 115.168382239656 -1.34609104969172 0.178974218684838 PAFAH1B3 other 6.77710477806352e-17 1 1 3.51090627974025 -1.34609104969172 0.805531462995966 -14.1050013994444 48.4183257852474 -0.291315347457595 0.770948056968129 -63.5443097628596 96.6010776584301 -0.657801251322938 0.511011404736387 SCGN other 1 1 1 -0.291315347457595 -0.657801251322938 0.0701317438779196 -154.794274996367 68.5567542923213 -2.25789970068208 0.0244434128399756 -80.4280764060452 134.301533186865 -0.598861937742278 0.549574547027466 CARMIL1 other 1 1 1 -2.25789970068208 -0.598861937742278 2.49054581372825e-18 200.486981670318 110.815934434002 1.80918910889769 0.0711070914836174 -488.095796098704 142.298456886989 -3.4300849550768 0.000660576283865998 PGM1 other 2.09380186560134e-14 1 1 1.80918910889769 -3.4300849550768 0.000366523935052353 -612.388960401993 538.412492024975 -1.13739738485411 0.255995446086485 -2266.22334250512 692.693300702715 -3.27161146239772 0.00115411498560005 EPB41L2 other 1 1 1 -1.13739738485411 -3.27161146239772 0.0980270901249223 -134.906912906229 123.197190806413 -1.09504861290397 0.27410127243769 -363.956060421211 173.889318686569 -2.09303287384335 0.0369249153491749 RIMS1 other 1 1 1 -1.09504861290397 -2.09303287384335 0.524090459784744 -169.67876887532 403.251731954031 -0.420776292895533 0.674124822275115 159.839590725307 515.204113976244 0.310245175434832 0.756522085240661 MOXD1 other 1 1 1 -0.420776292895533 0.310245175434832 1.35119567689138e-19 -162.581854938517 116.991509853336 -1.38968934705036 0.165329174394427 -1048.4879803064 149.471167512808 -7.01465036871783 8.79670592228416e-12 STX7 other 1.14973240146688e-15 8.39909481459692e-08 1 -1.38968934705036 -7.01465036871783 0.184737764568557 52.5090083287395 41.2733073574825 1.27222681414748 0.20397219470144 -9.13581207100952 60.6263797370002 -0.150690377862591 0.880289814449028 RABL2B other 1 1 1 1.27222681414748 -0.150690377862591 0.875899749445944 -4.0930141029046 18.4877179239874 -0.221390986152704 0.82489213610606 -9.3514637825613 22.8771676501614 -0.408768424726535 0.682911239330251 PTPRH other 1 1 1 -0.221390986152704 -0.408768424726535 1.29252220976458e-09 408.118152318057 63.4421790539981 6.43291511110758 3.29812747771576e-10 290.395874583001 83.9917459731678 3.45743348013948 0.00059888957463145 DCT other 9.16398246723086e-06 1 3.12398634689237e-06 6.43291511110758 3.45743348013948 0.000341144198580056 353.501983409819 103.693265197495 3.40911227683435 0.000712642764438628 -79.4779949030694 205.980247852291 -0.385852506401794 0.699794973492512 CRYBG3 other 1 1 1 3.40911227683435 -0.385852506401794 0.718791555930355 -4.99394589834591 8.19288736566573 -0.609546509729189 0.542481964394602 -12.2871753946632 16.2751496794336 -0.754965431143779 0.450680156650826 EPHA6 other 1 1 1 -0.609546509729189 -0.754965431143779 3.99445880420184e-12 353.978735293145 73.6697041902771 4.80494307916419 2.13308427036032e-06 -75.4346193164958 84.8224762423998 -0.889323474840843 0.374319663284665 RFX3 other 3.04018259587802e-08 1 0.0189524537421515 4.80494307916419 -0.889323474840843 1.63987623444775e-12 112.262074214525 73.9970184225793 1.5171161839714 0.129962052468667 -647.681069821474 123.275960424956 -5.25391217873129 2.33418661080455e-07 RAB21 other 1.2569651337042e-08 0.00209866718177437 1 1.5171161839714 -5.25391217873129 0.00350091689635932 529.526274172509 1060.82135016998 0.499166305511915 0.617912847574452 -3460.49719779152 1576.81305800001 -2.19461475171998 0.0287155531940688 SLC4A4 other 1 1 1 0.499166305511915 -2.19461475171998 3.51027113065337e-09 426.944701115005 201.414362252184 2.11973315279494 0.0345955708416692 -683.612262543881 232.048609529485 -2.94598732537123 0.00339255066850409 SMARCA2 other 2.44209562559555e-05 1 1 2.11973315279494 -2.94598732537123 0.0492948402900167 -156.831173357152 179.307391752482 -0.874649794547478 0.382243824631728 -540.729810575538 245.905925850639 -2.1989295650564 0.0284050286206426 SESN1 other 1 1 1 -0.874649794547478 -2.1989295650564 5.31074905751306e-10 105.984936825178 17.1400607916583 6.18346329767735 1.44627933022547e-09 46.2873117390305 19.7409144571708 2.34473999871961 0.0194891473419977 PUM3 other 3.82533254612666e-06 1 1.36123810560821e-05 6.18346329767735 2.34473999871961 0.590164541580513 -9.16954324572988 13.3001150387842 -0.689433378507685 0.490916495996164 -24.7225365173382 24.3740844759419 -1.01429600532238 0.311002772148516 CHRNA3 other 1 1 1 -0.689433378507685 -1.01429600532238 5.1988449449155e-15 -176.494358682816 179.526681618939 -0.983109346706694 0.326096354533874 -1082.39024941327 205.993154369964 -5.25449621238043 2.32264591014496e-07 PSEN1 other 4.17987133571206e-11 0.00208875546699336 1 -0.983109346706694 -5.25449621238043 0.00705687051689898 -174.455230524642 152.858628706301 -1.14128480675982 0.254376439197524 -956.428480581422 303.617222471001 -3.15011273997401 0.00174414917418511 CPOX other 1 1 1 -1.14128480675982 -3.15011273997401 0.0163031042340739 -1075.66810387924 811.858516062401 -1.32494527383458 0.185884855397252 -4826.23477804439 1674.64227510794 -2.88194968548332 0.00414791450437084 CLDND1 other 1 1 1 -1.32494527383458 -2.88194968548332 0.167173872807997 19.5319532745231 46.3480744050363 0.421418872849672 0.673657397445239 -42.4727984688827 54.8841346402863 -0.77386295233134 0.439432198770107 MOK other 1 1 1 0.421418872849672 -0.77386295233134 1.48918295873892e-06 -410.226312296929 2213.47233368071 -0.185331574311922 0.853055554599211 -8673.26683418282 2621.43296642032 -3.30859760493001 0.0010157588546102 HSP90AA1 other 0.00889786817846504 1 1 -0.185331574311922 -3.30859760493001 3.38943037637079e-12 17.7139302689927 15.4110109667238 1.14943336989646 0.251004578653942 -58.3585145649118 19.6917535994136 -2.96360170618068 0.00320640604795766 CROCCP3 other 2.58308488983218e-08 1 1 1.14943336989646 -2.96360170618068 4.37488299884581e-18 238.675176665058 25.7158643492631 9.28124263775319 7.97993954917747e-19 196.584674687211 49.88066532575 3.94109969069974 9.44806647696375e-05 NDC80 essential 3.6630895349336e-14 0.753766743532168 7.79320896372672e-15 9.28124263775319 3.94109969069974 1.6642086297976e-08 29.8242820043861 16.9088667796154 1.76382500336101 0.0784617426624359 -89.9280823963434 26.0512897510728 -3.45196277250112 0.000610831488724435 AP4E1 other 0.000112517145460616 1 1 1.76382500336101 -3.45196277250112 6.87234768166412e-48 45.9165707891374 36.6528223593469 1.25274311317606 0.21096762378872 -371.504522442347 47.0657950855814 -7.89330174422479 2.38330795442195e-14 RSBN1 other 6.53285370618992e-44 2.30894874624398e-10 1 1.25274311317606 -7.89330174422479 2.76387279380358e-32 -27.5430818452626 59.9836102912575 -0.459176793652866 0.646335007438171 -570.866219763556 77.0247999671916 -7.41145994545541 6.49846778765459e-13 MAGI3 other 2.52341586074267e-28 6.25152601172372e-09 1 -0.459176793652866 -7.41145994545541 0.470389065691855 -2.16698751474457 83.4605644131378 -0.0259642087251864 0.979297738221528 -110.332862261592 119.756387446021 -0.921310876309821 0.357396474735437 CXCL2 other 1 1 1 -0.0259642087251864 -0.921310876309821 0.767546422556477 -8.81782853893087 63.0725856530287 -0.139804456209216 0.888878755671399 -92.606198758351 134.379842409625 -0.689137575232922 0.491101589392124 COL4A4 other 1 1 1 -0.139804456209216 -0.689137575232922 1.6852737604577e-05 57.9371370809288 74.0234428117307 0.782686333953483 0.434235248284179 -240.036342449593 98.0526133424983 -2.44803615392835 0.0147560604305436 OSTM1 other 0.0916114816184807 1 1 0.782686333953483 -2.44803615392835 0.0692738626167753 -29.8752882913976 23.432089892897 -1.27497327075609 0.202994598700964 -83.0032759763562 36.187422490009 -2.29370511257807 0.0222801188755203 CDH7 other 1 1 1 -1.27497327075609 -2.29370511257807 0.217714862863962 3.82471951932794 2.64889166473033 1.4438942785972 0.149483597572784 -1.25671292603814 5.31133418961303 -0.236609650452008 0.813070246639892 IMPG2 other 1 1 1 1.4438942785972 -0.236609650452008 0.00107359516451614 111.212385459315 121.222002805703 0.917427388471457 0.359423608602203 -685.284929370266 243.0641375818 -2.81935844665544 0.00503021920435476 PCNP other 1 1 1 0.917427388471457 -2.81935844665544 2.44665760241429e-27 -61.6857240114804 126.104384152292 -0.489163992403188 0.624971020314751 -953.419775412149 143.663457686415 -6.63648077782765 9.53507678777268e-11 EXD2 other 2.19244987752345e-23 9.01732211819662e-07 1 -0.489163992403188 -6.63648077782765 5.01285868498041e-18 88.4553004348728 49.6797933643972 1.78050862220904 0.0756889929548155 -187.777685066115 56.6566146986912 -3.31431177215135 0.000995368995701341 ARG2 other 4.19375757585461e-14 1 1 1.78050862220904 -3.31431177215135 2.49208128349271e-06 34.2579449152573 55.5549424728242 0.616649813506967 0.537786839568461 -516.783320493065 117.127547744282 -4.41214155376435 1.29073964855558e-05 UBA5 other 0.0146534379469371 0.10868027840838 1 0.616649813506967 -4.41214155376435 2.8803924660193e-09 265.989986525405 60.9916242096374 4.36109039515257 1.61588732635689e-05 -365.173610927632 133.004413802973 -2.7455751315786 0.00628970888848013 CDC14B other 2.01569864772031e-05 1 0.139160216545855 4.36109039515257 -2.7455751315786 7.18479996404339e-05 103.951412190548 37.9044240820432 2.74246119570495 0.00634861759591618 -181.314697878411 82.6581644758827 -2.19354856266272 0.0287939380043281 ZNF510 other 0.36261685418527 1 1 2.74246119570495 -2.19354856266272 0.0325355954660277 25.2247166596137 58.0959842861775 0.434190365643143 0.66436401027485 -243.029672114275 106.976731820255 -2.27179937149902 0.0235828386187309 AACS other 1 1 1 0.434190365643143 -2.27179937149902 1.22824333628657e-06 103.619269761415 90.8531753739221 1.14051346400334 0.254698544791803 -770.615915847241 179.915570048999 -4.28320859410538 2.26799806072463e-05 KIAA0141 other 0.00738542718109117 0.188402598904395 1 1.14051346400334 -4.28320859410538 0.872704992507259 9.22564421338445 109.424263702234 0.0843107725950918 0.932847956658873 -103.391809140225 230.701267982338 -0.448163159415927 0.654257555483336 PCDHB4 other 1 1 1 0.0843107725950918 -0.448163159415927 0.00186668173143693 -119.33512450446 143.25721220269 -0.833013030685089 0.405294505366357 -1067.9096258672 302.044869027259 -3.53559929458964 0.000450514882228974 PCDHA6 other 1 1 1 -0.833013030685089 -3.53559929458964 0.000190756556194378 -1860.99158001798 2808.41990973689 -0.66264719658405 0.507905869802924 -24169.2079360513 5921.04540877906 -4.08191565297168 5.31138631497306e-05 PCDHGA2 other 0.911244068940544 0.431656365817861 1 -0.66264719658405 -4.08191565297168 1.48921565465892e-50 84.6163296505854 16.9259891684885 4.99919554528119 8.3413923677721e-07 -101.736596846811 21.7346192338092 -4.68085480368368 3.81483848061282e-06 HSPB11 other 1.42309447959206e-46 0.0329258709261692 0.0074997458778639 4.99919554528119 -4.68085480368368 9.51565146644942e-11 301.396789352206 319.241350880796 0.944103226354117 0.345637381662097 -2367.80849561133 507.876823498088 -4.66217079823144 4.16013040707475e-06 PHLPP1 other 7.00922887018664e-07 0.035843683587356 1 0.944103226354117 -4.66217079823144 0.838670361639224 -4.6026533703113 9.57104844208019 -0.480893331400897 0.630832436616644 -0.704569146948301 15.2901476635074 -0.0460799439255826 0.963267533109032 ATP8B1 other 1 1 1 -0.480893331400897 -0.0460799439255826 0.0377958746545153 2.86929316785679 4.60448459285725 0.623151866401683 0.533509063330481 11.0090830290452 5.91295282628298 1.86185876202327 0.0632925222277315 IL12RB2 other 1 1 1 0.623151866401683 1.86185876202327 1.64780064822626e-06 79.850888252149 29.6828378061238 2.69013659589095 0.00741651405847249 -165.820143266478 63.7106535086884 -2.60270667673915 0.00956426967355916 WDR70 essential 0.00982253966407675 1 1 2.69013659589095 -2.60270667673915 0.108556493424775 174.914603247725 87.9975170452931 1.98772203035792 0.047468949529355 297.370454203173 183.438847351172 1.6210876730701 0.105723428401403 C1QTNF3 other 1 1 1 1.98772203035792 1.6210876730701 1.34628733309773e-09 196.854640875202 83.9351472937832 2.34531834663002 0.0194562440487885 -389.825173522662 129.625511457346 -3.00731830594117 0.0027873898373352 ME2 other 9.53440689299815e-06 1 1 2.34531834663002 -3.00731830594117 0.00484981996762681 20.7540514775988 24.0788607552496 0.861919992334941 0.389208623913589 -121.653247292904 51.9564540581888 -2.34144630341128 0.0196618265673502 C5orf22 other 1 1 1 0.861919992334941 -2.34144630341128 2.31588544937503e-07 20.4876758608683 65.7192006383657 0.311745664309069 0.755383524518451 -355.933803353052 93.5615276143803 -3.80427524462892 0.000162624924793494 FAM135A other 0.00146201848419046 1 1 0.311745664309069 -3.80427524462892 0.0771386068519818 -377.674438472082 180.241760030229 -2.09537700036185 0.036711097210186 -662.367956615135 360.036538344833 -1.83972426704297 0.0664852546502208 EPB41L3 other 1 1 1 -2.09537700036185 -1.83972426704297 0.0183519163790342 26.3439851574531 15.9540337496236 1.65124291266305 0.0994090208748104 -35.6216852267674 29.6143890342434 -1.20285058677313 0.229686922090124 MRPL22 other 1 1 1 1.65124291266305 -1.20285058677313 0.000304437926647688 91.6352604393564 41.264020672369 2.22070605205752 0.0268829235822895 -135.734076482668 75.006343478732 -1.8096346280519 0.0710393731700376 GEMIN5 essential 1 1 1 2.22070605205752 -1.8096346280519 0.452015477500798 35.8151750972525 501.243194197158 0.0714526910527288 0.943070163854373 -1384.10258224267 1131.898305253 -1.22281531460841 0.22205850573629 NFE2L1 other 1 1 1 0.0714526910527288 -1.22281531460841 0.0324994944027257 321.771128423043 183.548034963611 1.75306223510829 0.0802908833082216 -323.258953864833 355.379778461889 -0.909615497156094 0.36352558581257 SEMA5B other 1 1 1 1.75306223510829 -0.909615497156094 0.0102472121602514 71.2252230615498 189.339911153666 0.376176489296776 0.706967834439464 -949.841869865279 376.067558528845 -2.52572137192851 0.0118977545248335 GSK3B other 1 1 1 0.376176489296776 -2.52572137192851 0.305248482464576 -232.887275731828 237.331463171441 -0.98127434356901 0.326999171009807 -694.402519222996 459.513515470889 -1.51116886847475 0.131466535143661 ITGB5 other 1 1 1 -0.98127434356901 -1.51116886847475 0.00265363251656015 73.7403035413162 168.789516020525 0.436877273422297 0.662416143115002 -1039.32715008431 352.30716242568 -2.95005966648083 0.00334783491832473 RNF13 other 1 1 1 0.436877273422297 -2.95005966648083 0.00551365660558207 -52.4141601658942 157.467953816202 -0.332856044011803 0.739402573423621 953.287123531151 340.2788814242 2.80148776656745 0.00531266912864603 TRPM3 other 1 1 1 -0.332856044011803 2.80148776656745 1.72923830146641e-12 -129.377110456354 135.198133195869 -0.956944503582143 0.339124358036979 -1097.70407701796 186.513642793518 -5.88538221964373 7.91617709576509e-09 DOPEY1 other 1.32476946275342e-08 7.32246381358271e-05 1 -0.956944503582143 -5.88538221964373 4.13147030957775e-23 84.7099913465682 100.836360158281 0.840073870314245 0.401325289765664 -973.737660769208 141.5597755447 -6.87863241533419 2.09548933384071e-11 LYRM2 other 3.61834169712819e-19 1.99490584581636e-07 1 0.840073870314245 -6.87863241533419 0.547328768338675 -42.2515823008829 86.8768443331284 -0.486338823943347 0.626970753632812 40.5383823008871 120.710840176933 0.335830504049742 0.737159862628022 BCKDHB other 1 1 1 -0.486338823943347 0.335830504049742 0.0130486994178133 42.6427174316257 29.8292270142404 1.42956159780031 0.15355574000629 -114.083825132927 64.09616121237 -1.77988545608734 0.0757879182513438 ZCCHC6 other 1 1 1 1.42956159780031 -1.77988545608734 0.52969177040934 -85.9743808710506 86.154919628525 -0.997904486960781 0.318876647386239 37.4483696125765 67.3006536969005 0.556433965429687 0.578198389262924 ULK2 other 1 1 1 -0.997904486960781 0.556433965429687 1.28293465027344e-27 205.183709944602 207.422517738695 0.989206534476098 0.323108242307433 -1449.18027491635 265.02410422548 -5.46810743555387 7.65678632614583e-08 PLOD1 other 1.1509206747603e-23 0.000696920691405793 1 0.989206534476098 -5.46810743555387 0.00175996445070346 -5.45264709134371 16.0869449091686 -0.338948577379414 0.734810906478559 -41.5512029563392 11.7235793859033 -3.54424204320239 0.000436101802951396 P2RX5 other 1 1 1 -0.338948577379414 -3.54424204320239 4.48362938425505e-07 102.166675880752 19.1477919678619 5.33568967389192 1.52985044795296e-07 13.9658376294003 13.954213212482 1.00083303993864 0.317460121938353 ITGAE other 0.00278254039586868 1 0.00139552957862269 5.33568967389192 1.00083303993864 4.29121590280094e-15 251.200755111596 99.7437223526609 2.51846180578095 0.0121454750765183 -370.162403711112 115.821345942785 -3.19597739689511 0.00149535901136121 DIS3 essential 3.45700353129644e-11 1 1 2.51846180578095 -3.19597739689511 8.48724646966396e-15 76.1729065716597 22.192513654896 3.4323694808161 0.000655720844974081 -56.854109035196 25.7697100202029 -2.20623782691476 0.0278904837084573 PIBF1 other 6.79998187149477e-11 1 1 3.4323694808161 -2.20623782691476 3.66015973410554e-22 72.6679139461604 30.1576769827987 2.40959918721885 0.0163844174396022 -154.915677711989 35.2859346053975 -4.39029543766972 1.42282001869807e-05 TDRD3 other 3.18873116035274e-18 0.119431512369516 1 2.40959918721885 -4.39029543766972 1.11088120624051e-21 76.828040280852 22.2895590123895 3.44681741967832 0.000622007213097947 -93.8846800695417 26.7149226042088 -3.51431600459702 0.000486780918020585 NUFIP1 other 9.63911622654891e-18 1 1 3.44681741967832 -3.51431600459702 9.95197435120626e-11 205.514745282563 83.8435094791439 2.45117059816879 0.014630850168826 -223.351357098273 100.019488116429 -2.23307838606692 0.0260505508403177 PDS5B other 7.32664351735805e-07 1 1 2.45117059816879 -2.23307838606692 0.0644899403441993 -28.6263353597353 134.554668649559 -0.212748733633994 0.831623305704527 -637.697665434369 295.667570902839 -2.15680625199145 0.0315718005002749 OXCT1 other 1 1 1 -0.212748733633994 -2.15680625199145 0.153294014536441 -101.591556001429 84.7117734074145 -1.19926135311597 0.231074702998468 -373.046496403729 207.965491275706 -1.79379037414035 0.0735362712137635 CYLD other 1 1 1 -1.19926135311597 -1.79379037414035 1.72583140336676e-39 159.666155094279 32.763828576813 4.87324473450808 1.53957548537177e-06 -89.0041235834864 40.686606578705 -2.18755337610461 0.0292324958258014 SLC27A5 other 1.6093377836395e-35 1 0.0137360924804869 4.87324473450808 -2.18755337610461 2.83921548879122e-46 70.6053141519532 23.5785196361816 2.99447612663554 0.00290567820818565 -141.393528350927 29.2801541766248 -4.82898851891311 1.90258529775887e-06 ZNF324 other 2.69186020492295e-42 0.0166171799906259 1 2.99447612663554 -4.82898851891311 8.70452591916159e-53 42.2719463226641 19.0775472499866 2.21579565594805 0.0272200917724381 -146.244444188031 23.9282010238956 -6.11180272357234 2.18372665218055e-09 ZNF671 other 8.35199261943555e-49 2.03501486716706e-05 1 2.21579565594805 -6.11180272357234 5.2356944533656e-75 51.5297117670135 7.90490657106842 6.518699658717 1.95984255699228e-10 -41.1324625574045 9.91480671121238 -4.14858945367931 4.02135616092586e-05 ZNF416 other 5.12679200873559e-71 0.329188215333391 1.85989058658567e-06 6.518699658717 -4.14858945367931 5.46925532170499e-22 8.597019165215 7.64083319407753 1.12514158428149 0.261146623818902 -36.1188643881431 9.53298627439742 -3.78883000022217 0.000172572945625913 ZNF586 other 4.75934598094769e-18 1 1 1.12514158428149 -3.78883000022217 2.99660424716129e-58 127.634220575545 29.1760116540424 4.37462879056196 1.52350962298611e-05 -171.756484653688 36.2312024957861 -4.74056815182065 2.89040175889761e-06 ZNF446 other 2.89442004233309e-54 0.0250540024461245 0.131356999693863 4.37462879056196 -4.74056815182065 1.86451752491694e-71 138.498242906789 35.4039050968103 3.91194820255199 0.000106134051357998 -279.631710669644 44.1844450323083 -6.32873651496977 6.13232234300314e-10 ZNF264 other 1.82200652534883e-67 5.76009037678285e-06 0.880488090065952 3.91194820255199 -6.32873651496977 1.3550727810068e-20 1961.84798953228 714.631792910931 2.74525708063032 0.00629628021988332 -1808.48373071918 892.200352110743 -2.0269928457669 0.0432711364144166 RPS5 essential 1.16454954799724e-16 1 1 2.74525708063032 -2.0269928457669 0.000626903104908057 142.984700494756 587.591875098278 0.243340159308433 0.807855820612283 -1940.41254490046 773.825006433282 -2.50755988598018 0.0125176352301698 FAT1 other 1 1 1 0.243340159308433 -2.50755988598018 3.68608952846702e-07 33.5819785735694 104.625069521019 0.320974492321105 0.748384581489064 -615.20458121067 155.577367407899 -3.95433212080071 8.96361454565036e-05 YTHDC1 essential 0.00229643377623495 0.71628243834292 1 0.320974492321105 -3.95433212080071 0.000550001362953991 64.8552874627568 51.9943444848213 1.24735272855858 0.212947106211379 -241.606744807535 88.4627939074556 -2.73116791970519 0.00657066076363917 CHMP2B other 1 1 1 1.24735272855858 -2.73116791970519 3.75658303020942e-18 -310.6999196363 197.627994259767 -1.57214528640061 0.116638915771942 -1595.22256535693 253.788449856835 -6.28563894951411 7.89923071563937e-10 SMAP2 other 3.14876789592154e-14 7.4078985651266e-06 1 -1.57214528640061 -6.28563894951411 4.42715718251406e-56 220.428572554335 38.7338063749259 5.69085750108537 2.31684294089282e-08 -232.340238266604 49.7379813170637 -4.67128403916334 3.98811698619493e-06 PPIE essential 4.26512322963405e-52 0.0343775684210003 0.000214261635173768 5.69085750108537 -4.67128403916334 1.93008102355947e-50 199.286716826722 68.7414092831231 2.89907813798123 0.00393070832607121 -592.808640502258 88.2758324208207 -6.71541263611397 5.83640363371777e-11 ZMPSTE24 other 1.84380640180636e-46 5.53174336403771e-07 1 2.89907813798123 -6.71541263611397 2.06507320278981e-05 135.940658959331 34.3853493292248 3.95344708171372 9.01162076939988e-05 -1.70034011956504 61.5282403896078 -0.0276351169608976 0.977966053667078 NOA1 other 0.11112158904212 1 0.750487777675622 3.95344708171372 -0.0276351169608976 3.03535895678618e-06 116.984453499557 53.3653671020239 2.19214183003569 0.0289071501019479 -260.020861347058 95.4905853680626 -2.72299997266561 0.00673369878846882 REST other 0.0177113195128473 1 1 2.19214183003569 -2.72299997266561 0.0786274973826601 93.6998630846456 77.8187298904514 1.20407854531359 0.229210994319065 -113.014614560204 130.177329460045 -0.868158956931837 0.385783822432269 SSH1 other 1 1 1 1.20407854531359 -0.868158956931837 6.76828989784784e-79 765.915670450518 116.976100937028 6.54762523554133 1.64354614117536e-10 -996.899924668489 150.271043562181 -6.63401212260819 9.68115317879707e-11 EIF3I essential 6.64239970574787e-75 9.15449844587051e-07 1.56104012488836e-06 6.54762523554133 -6.63401212260819 0.128102736658952 136.585879998109 70.2440369685756 1.94444803989856 0.0524812488585879 176.639149378066 90.2001875199087 1.95830135429684 0.0508289733384439 NKAIN1 other 1 1 1 1.94444803989856 1.95830135429684 0.938937873870611 91.1428842039476 278.573416068103 0.327177250041927 0.743690489886756 125.28852631506 357.863850871304 0.35010109573799 0.726431504338489 COL16A1 other 1 1 1 0.327177250041927 0.35010109573799 4.58723187292852e-62 376.284998391403 98.5822243077673 3.81696600004343 0.00015460408366977 -917.962359731305 126.641712321938 -7.24849927327053 1.92555959419573e-12 TXLNA other 4.45007363992796e-58 1.84834465446848e-08 1 3.81696600004343 -7.24849927327053 0.343667992754898 -130.107172249831 477.448670859405 -0.272505046491466 0.785363016975725 -766.038261065305 599.871487884684 -1.2770039525742 0.202282068336372 CD59 other 1 1 1 -0.272505046491466 -1.2770039525742 2.17887558095348e-09 562.236858915795 228.221694278322 2.46355571363927 0.014147213664478 -1040.33604634571 299.919475880916 -3.46871787265586 0.000575690098576274 CD82 other 1.5315316458522e-05 1 1 2.46355571363927 -3.46871787265586 6.6975053034131e-06 8.90487165451954 59.7025035205073 0.149154074442804 0.881500864749485 -248.506986257959 79.476883081692 -3.12678324340583 0.00188531201844394 PREP other 0.0378743924908011 1 1 0.149154074442804 -3.12678324340583 8.22786449976683e-14 56.4081415113377 38.6106524349268 1.4609476389037 0.144748423151734 -209.324508081012 51.3990892898565 -4.07253340425083 5.52180177358755e-05 HACE1 other 6.48602558516619e-10 0.447597251767007 1 1.4609476389037 -4.07253340425083 5.55934717551858e-11 60.9850012083236 42.5858190932014 1.43204950631229 0.152847794993021 -287.496300973675 66.8052759104197 -4.30349694774382 2.07856028315521e-05 SEH1L essential 4.117950367276e-07 0.172957001161345 1 1.43204950631229 -4.30349694774382 7.86184278043008e-05 -37.7950278780688 118.16357610864 -0.319853453346063 0.74923228717045 -400.305798084261 152.519665874749 -2.62461759136685 0.00897858441730425 WDR47 other 0.39466450757759 1 1 -0.319853453346063 -2.62461759136685 2.21918471654309e-22 3.40315844221344 10.6489754235501 0.319576138253393 0.749442035998463 -73.7391474517591 13.6743220001553 -5.39252677031603 1.13856962154722e-07 OVGP1 other 1.93601674671219e-18 0.0010319995049704 1 0.319576138253393 -5.39252677031603 1.34921528931433e-09 -5.37769997557318 20.1932080926392 -0.266312314066305 0.790124011085287 -97.3385378096736 26.0533919028124 -3.73611766839334 0.000211603821012605 SLC25A24 other 9.55379346363475e-06 1 1 -0.266312314066305 -3.73611766839334 6.2987386275876e-11 329.255840111587 88.3270902892384 3.72768806300984 0.000218579269856027 -102.134185123523 116.024334362649 -0.88028244837233 0.379189053463188 MAP3K4 other 4.65854708896379e-07 1 1 3.72768806300984 -0.88028244837233 0.0271570763317689 -3.96569968485594 7.50552639292144 -0.528370626821864 0.597510952829775 -17.9511958384786 9.64543718594743 -1.86110753638331 0.0634018316997742 TTC39A other 1 1 1 -0.528370626821864 -1.86110753638331 1.43190082446719e-18 -22.7086521032177 182.210958523617 -0.124628355436012 0.900875217789501 -1215.80223436919 234.161371637883 -5.19215541771492 3.1950947979236e-07 EPS15 other 1.20709239502584e-14 0.00286376346737892 1 -0.124628355436012 -5.19215541771492 4.83720192522485e-17 71.8706466963324 13.4093539784215 5.35973968708617 1.35194913723131e-07 10.7745616867169 17.2252611508398 0.625509337267234 0.531963338895454 ORC1 other 4.00665435466374e-13 1 0.00123446475720591 5.35973968708617 0.625509337267234 0.0298843288827162 41.2025389497981 34.3239093526987 1.20040344258043 0.230631515306197 -42.9878822850542 46.4758234348845 -0.924951493227074 0.355500450054829 MGST2 other 1 1 1 1.20040344258043 -0.924951493227074 1.30414234964791e-05 32.4731157128362 30.4426076603853 1.06669954410946 0.286699189528414 -125.862170369928 46.9575040848795 -2.68034199906414 0.00763402522250785 ATG16L1 other 0.071675663536649 1 1 1.06669954410946 -2.68034199906414 1.01394515377087e-12 47.9454372736431 57.4892174448152 0.833990083786872 0.404743250640587 -448.252223475629 89.2742366642192 -5.02107035831186 7.50376480079423e-07 USP40 other 7.80737768403573e-09 0.00664608448406345 1 0.833990083786872 -5.02107035831186 2.94768463150147e-55 304.321313180665 99.7079516117209 3.05212681898975 0.0024105185330237 -914.625577673056 128.034724664623 -7.14357437069392 3.81803626167025e-12 POMGNT1 other 2.83773599474646e-51 3.6565333278016e-08 1 3.05212681898975 -7.14357437069392 5.04822866442172e-22 137.912252360163 20.7848691350542 6.63522351110552 9.58683587953883e-11 33.5939126962864 26.6897970912088 1.2586799585431 0.208816415096122 RAD54L other 4.39397822951266e-18 1 9.1218743393812e-07 6.63522351110552 1.2586799585431 6.25633067025419e-18 185.48042557159 82.6129938529355 2.24517254394357 0.0252552121616824 -316.625071222119 106.59363550103 -2.97039377382958 0.00313773527247403 MAST2 other 5.2277899080644e-14 1 1 2.24517254394357 -2.97039377382958 1.68511015906708e-09 941.983011208924 231.925186199582 4.06158135148938 5.78185680347495e-05 -416.418583543544 269.949779085858 -1.54257797488733 0.123660332104961 DNAJA1 other 1.18833968417411e-05 1 0.486311975740278 4.06158135148938 -1.54257797488733 0.168580662176182 -123.458536575181 66.03277297558 -1.86965549093081 0.0622032281229476 -104.976792843659 76.8589766781291 -1.36583646284132 0.172696049147909 B4GALT1 other 1 1 1 -1.86965549093081 -1.36583646284132 1.93538587487551e-21 327.425159069574 57.2525446335669 5.71896255730102 1.99510329470372e-08 -227.860710351203 66.655617159974 -3.4184772425756 0.00068904882788015 CHMP5 other 1.67623770622968e-17 1 0.000184746565089564 5.71896255730102 -3.4184772425756 1.37402015551164e-10 211.709189527485 44.8016267774093 4.7254799603446 3.10428989680448e-06 -61.9190341944211 52.1597791282834 -1.18710307499837 0.235834822405187 NFX1 other 1.00701937197448e-06 1 0.0274636527170292 4.7254799603446 -1.18710307499837 0.0105005894846912 -18.1865056818182 35.0985901351101 -0.518154877783132 0.604612446296418 -144.869179095644 53.6312399319452 -2.70120883424427 0.00717742881444873 AQP6 other 1 1 1 -0.518154877783132 -2.70120883424427 3.11865121663157e-50 583.184890910461 48.0795619855705 12.1295799467866 2.15248836634427e-29 -331.600024429541 98.3280249135647 -3.37238569289919 0.000811363560608967 SEPHS1 other 2.97831191188315e-46 1 2.11611131295306e-25 12.1295799467866 -3.37238569289919 3.58753120704164e-20 230.818409546367 59.3507443428014 3.88905669342903 0.000116362986368346 -162.328384040808 81.0371460303276 -2.00313550010829 0.0457826483477795 ITPKC other 3.07092671322765e-16 1 0.963601890116276 3.88905669342903 -2.00313550010829 0.00629517170597807 3.06660482374769 3.17534722743794 0.965754169260415 0.334700126010175 -13.4387755102041 6.03028232932772 -2.22854831271264 0.0263507820408186 FAT2 other 1 1 1 0.965754169260415 -2.22854831271264 1.25512337641279e-06 242.72313399281 71.5551840846356 3.39211109715988 0.000756684257064211 -310.50236061151 137.841045490199 -2.25261176384204 0.0247790402127254 RBM22 essential 0.00754329149224088 1 1 3.39211109715988 -2.25261176384204 2.38187311514529e-08 833.51391746061 147.75434234818 5.64121435765624 3.04205032310902e-08 -12.2817280176526 272.090119012948 -0.0451384565606668 0.964017614760542 TMED2 essential 0.000159394948865522 1 0.0002807204038165 5.64121435765624 -0.0451384565606668 0.0555771843637315 -36.310014959992 26.7472178314515 -1.35752492796824 0.175313492564539 -125.005435006381 53.8207664017128 -2.32262458087931 0.0206567327292587 ERO1B other 1 1 1 -1.35752492796824 -2.32262458087931 3.33723713423186e-14 266.577301023641 83.5396653498964 3.19102668064461 0.00151989460769795 -700.796843550515 153.096635208986 -4.57748037763134 6.14280830847122e-06 ZFAND6 other 2.65076745572036e-10 0.0525264464775861 1 3.19102668064461 -4.57748037763134 2.08954558034177e-07 23.2960879904229 27.5691094736007 0.845006909371897 0.39856937208368 -178.474531926603 43.7914678113917 -4.0755549162062 5.45318824287672e-05 ACOX3 other 0.00132247339779831 0.442471694027017 1 0.845006909371897 -4.0755549162062 2.26288151748829e-09 329.226982524405 127.108905016173 2.59011736811449 0.00991412032192078 -66.926256361654 155.027848188164 -0.431704736560767 0.666168445716859 PPP1R15A other 1.58944797788377e-05 1 1 2.59011736811449 -0.431704736560767 2.43978772624167e-10 -21.1549520061457 76.3496914035827 -0.277079731656296 0.781849601583714 -315.989083716233 93.1195840812395 -3.39336871866349 0.000753160494244966 HSD17B14 other 1.77348169820507e-06 1 1 -0.277079731656296 -3.39336871866349 1.45163567779429e-15 2331.54050410471 4016.58811048607 0.580477868272771 0.561890927276666 -16877.0089835781 4898.81501022758 -3.44512069721818 0.000625820246176399 FTL other 1.17814751609785e-11 1 1 0.580477868272771 -3.44512069721818 1.19891760083291e-22 632.507271929848 97.294090865693 6.50098342357684 2.17755529574463e-10 221.972872066431 118.664333914394 1.87059468286878 0.0620679214666719 BAX og 1.0476141996078e-18 1 2.06584670907293e-06 6.50098342357684 1.87059468286878 0.277984217862494 -66.0084530041778 89.9372206619879 -0.733939213579416 0.463380272891736 -298.421153322768 190.454401732013 -1.5668902929462 0.117865795867226 NLK other 1 1 1 -0.733939213579416 -1.5668902929462 0.139544956492242 54.7543585802801 89.2863166546553 0.613244678824202 0.540034332796798 -314.993780317948 189.076023209873 -1.66596364240381 0.0964389031454921 PIGS other 1 1 1 0.613244678824202 -1.66596364240381 0.859033235782242 -10.6461529170189 23.2926165503154 -0.457061270640063 0.647853607470056 -21.7726347212396 44.669740931881 -0.487413498870336 0.626209185562418 ADAMTS2 other 1 1 1 -0.457061270640063 -0.487413498870336 0.269712442292391 6.06623434141331 135.342655895111 0.0448213041283495 0.96427017076362 -479.986241980242 306.21006159869 -1.5675064348777 0.117718501604517 ATXN7L3 other 1 1 1 0.0448213041283495 -1.5675064348777 1.46609937739942e-17 229.03038318844 24.8722666865997 9.20826340736502 1.3796126246176e-18 100.375789806395 69.8990875045454 1.43601001658095 0.151713288536412 PGS1 essential 1.22067434162276e-13 1 1.3467778441517e-14 9.20826340736502 1.43601001658095 4.33799691584638e-05 79.0624360594574 25.8711409996616 3.05600885791978 0.00238017689998512 -88.2824717658618 52.336896811261 -1.6868113538376 0.092351660523061 UIMC1 other 0.224925140086635 1 1 3.05600885791978 -1.6868113538376 0.188097525708948 -1.92903171813526 11.3013214228461 -0.170690810920185 0.864545708364569 43.6022261277099 26.0450441110739 1.6741083617198 0.0948231819825984 CETP other 1 1 1 -0.170690810920185 1.6741083617198 0.868174636598191 101.853608773276 238.045439532682 0.427874648526053 0.668952683695203 -88.393862110005 544.572256814446 -0.162317967916834 0.871130320645092 MMP2 other 1 1 1 0.427874648526053 -0.162317967916834 0.0369511430272923 3542.51917618607 1679.31174059998 2.10950658566848 0.0354689795498774 8038.32677814901 3870.1967121853 2.07698144976465 0.0383869373472153 MT3 other 1 1 1 2.10950658566848 2.07698144976465 0.40946375227315 -85.8013293943932 83.3492923762447 -1.02941881026512 0.303852330786568 91.5107090103351 190.679516373338 0.479918927585086 0.63152515743166 LPCAT2 other 1 1 1 -1.02941881026512 0.479918927585086 0.00314337954627477 -532.176145541108 436.574227360146 -1.2189820474723 0.223507091775865 -3410.39058205104 998.742982546814 -3.41468289805099 0.000698040243222575 GNAO1 other 1 1 1 -1.2189820474723 -3.41468289805099 7.17389992776801e-05 150.574236937402 53.8420486612174 2.79659189576606 0.00539237115401081 -291.50116399379 124.086144738984 -2.34918382392301 0.0192589944836858 OGFOD1 other 0.362138468353729 1 1 2.79659189576606 -2.34918382392301 5.61327190664935e-06 487.397695256685 217.410953500097 2.2418267682013 0.0254736172021897 -885.704096315238 360.677071744358 -2.45567064197252 0.0144505626055393 SH3BP2 other 0.0319900365959946 1 1 2.2418267682013 -2.45567064197252 0.00064852459613467 91.1479216558352 39.5740919285764 2.30322206306943 0.021735080321402 -85.2429866575425 65.6520169014144 -1.29840621325536 0.194832565596595 NOP14 essential 1 1 1 2.30322206306943 -1.29840621325536 7.27413407646612e-15 197.549053148441 438.130988351093 0.450890392144863 0.652292188868958 -4872.7595741684 726.84379225108 -6.70399833653001 6.28054969680816e-11 ADD1 other 5.83603776954876e-11 5.9520769476651e-07 1 0.450890392144863 -6.70399833653001 2.5904932428968e-12 -5.79045885688201 24.6819145570998 -0.234603310188365 0.814626772363771 -172.867810017149 32.4986131218385 -5.31923652769617 1.66907244801143e-07 L2HGDH other 1.978100640276e-08 0.00150516953361671 1 -0.234603310188365 -5.31923652769617 7.68568682237824e-11 13.0747656965694 60.9558374198058 0.214495711157618 0.830260564809573 -332.672931536082 76.5858756681197 -4.34378961700067 1.74286218901901e-05 TXNDC16 other 5.67357401227961e-07 0.14575556486766 1 0.214495711157618 -4.34378961700067 0.953050092910199 -10.8665997756219 93.132161451014 -0.116679346922895 0.907167759514066 11.7089713000597 117.835911067741 0.0993667481666821 0.920892648809611 NID2 other 1 1 1 -0.116679346922895 0.0993667481666821 6.99407102029049e-12 62.8856640766601 23.4773178244227 2.67857105939258 0.00767190707659041 -42.825373309447 30.1471635403696 -1.42054403400506 0.156160815342805 ALG6 other 5.28472006293149e-08 1 1 2.67857105939258 -1.42054403400506 6.2666034551679e-69 348.925884955754 53.4519555810443 6.52784133270316 1.85392327908336e-10 -243.923918387412 66.369299811208 -3.67525224887517 0.000267145191865979 CNOT3 other 6.11432499120732e-65 1 1.75974397650593e-06 6.52784133270316 -3.67525224887517 1.79961056861941e-74 104.252238666709 114.087941530361 0.913788409785318 0.361331920795014 -1643.61356707113 145.839183164746 -11.2700409547305 4.90020822638091e-26 ASAP3 other 1.7618187466784e-70 4.82180489475882e-22 1 0.913788409785318 -11.2700409547305 0.00392988212313536 -201.154772539286 169.611820208655 -1.18597142753274 0.236279485927786 -670.379818031429 217.948102122013 -3.07586903260177 0.00223098146187179 DOCK9 other 1 1 1 -1.18597142753274 -3.07586903260177 9.7410811132674e-08 850.190414160558 216.697532991726 3.92339683070144 0.00010137672633331 -211.873836293482 296.642474061381 -0.714239715549435 0.475460285128136 ANKRD10 other 0.000628981607483676 1 0.842035088924474 3.92339683070144 -0.714239715549435 1.4181267246423e-18 85.3610692198463 12.195520191121 6.99937910659961 9.75866437680944e-12 0.375997987324026 16.1457731934371 0.0232877040213138 0.981431433833085 TGDS other 1.19562264154592e-14 1 9.34880047298345e-08 6.99937910659961 0.0232877040213138 0.000254335423163197 -174.213192954976 188.563786716138 -0.92389528227514 0.356051861862524 -1081.74247750594 288.147466154971 -3.75412802319825 0.000197509251095431 DOCK3 other 1 1 1 -0.92389528227514 -3.75412802319825 3.62032788358575e-13 10.9833476993053 42.490727237909 0.258488108189081 0.796152484346644 -390.322017838259 64.3094065098244 -6.06943896735589 2.79637571222425e-09 C3orf18 other 2.815891027853e-09 2.60258687536711e-05 1 0.258488108189081 -6.06943896735589 6.77100171977917e-05 253.321709891344 72.2945224027077 3.50402356184396 0.000505449003237582 -222.142397542473 169.27600683432 -1.31230882448625 0.19010323756157 COQ9 other 0.342748107055221 1 1 3.50402356184396 -1.31230882448625 0.0811505970507293 18.4243789662421 29.5450960456623 0.623601931696787 0.533214392987584 -60.3263788954677 45.9896421916144 -1.31173838326725 0.190297111686113 KIF9 other 1 1 1 0.623601931696787 -1.31173838326725 0.000526415032591062 47.6962352473382 13.7517100401206 3.4683857577119 0.000575389738639035 17.3861718086354 22.525767323826 0.771834830693897 0.440628482050085 ARHGAP28 other 1 1 1 3.4683857577119 0.771834830693897 2.50879670533974e-08 -143.607436997583 64.9783511783408 -2.21008127158283 0.0276218628840176 -400.507739240097 76.1469836663342 -5.2596665022881 2.27335885476038e-07 PPP1R13B other 0.000167587619916695 0.00204534096162791 1 -2.21008127158283 -5.2596665022881 4.27734853111859e-08 510.389975398228 86.1600388831814 5.92374355924132 6.41148489010212e-09 305.88815600294 234.202556037188 1.30608376432224 0.192215875769222 XRN2 essential 0.000281748947744781 1 5.98512114491033e-05 5.92374355924132 1.30608376432224 0.124280408811429 23.3553589622527 100.426062932178 0.232562726052753 0.816210604472124 -512.06289960133 272.980849780684 -1.87581986067055 0.0613510353980689 KIZ other 1 1 1 0.232562726052753 -1.87581986067055 0.110982094051742 520.543892820481 277.425449380581 1.8763379278387 0.0612751232824852 -11.4525777465567 520.616353829722 -0.0219981137017883 0.982459500933748 DYNLL1 essential 1 1 1 1.8763379278387 -0.0219981137017883 0.00718616988668096 85.2952816253729 28.2604983518379 3.01818037896793 0.00269206559887391 28.257434296703 55.5438089493795 0.508741385065178 0.611190843295342 TESC other 1 1 1 3.01818037896793 0.508741385065178 0.00258951455237303 610.129847110885 416.849480237741 1.46366944433494 0.144001561336363 -1355.53281341124 732.419293228129 -1.8507606584703 0.0648770803391713 RPL6 essential 1 1 1 1.46366944433494 -1.8507606584703 1.59121887874275e-15 84.5668774888722 39.5523880903599 2.13809788920138 0.033061594649998 -388.052655355888 67.9217073034093 -5.71323470451707 2.05029495701879e-08 MAPKAPK5 other 1.29047851066037e-11 0.000188463112449167 1 2.13809788920138 -5.71323470451707 0.0452065985252615 628.675870348142 304.17644473488 2.0668131317535 0.0393401990760048 -232.703181272493 586.994073108038 -0.396431909508673 0.691979934765645 P2RX7 other 1 1 1 2.0668131317535 -0.396431909508673 1.16987605080302e-09 838.629851940783 137.828396285211 6.08459413693959 2.55446668190961e-09 88.6460584234022 265.978688112819 0.333282561292285 0.739080846864718 ANAPC5 essential 8.31196934095548e-06 1 2.39838876764494e-05 6.08459413693959 0.333282561292285 3.20431630404829e-05 213.179027226319 57.8171115838129 3.68712689697911 0.000255415018337895 446.421038948763 104.064360427511 4.2898552118593 2.2038498551332e-05 SLC8B1 other 0.168995641875507 0.183206038457223 1 3.68712689697911 4.2898552118593 0.083352443262913 -78.9671087140137 44.5148681941756 -1.77394906280652 0.0767694403001346 -177.475843470789 86.4770005871743 -2.05228953670614 0.0407380541660801 LHX5 other 1 1 1 -1.77394906280652 -2.05228953670614 0.975250914788068 40.4647219516579 182.75700480243 0.22141270040731 0.824874290044064 47.7622006515989 323.755583042733 0.147525488835492 0.882785147267984 OAS1 other 1 1 1 0.22141270040731 0.147525488835492 0.000428707769700897 462.938387985534 155.326614533588 2.98041896667637 0.00303920417593358 -303.694908132683 291.485787953999 -1.04188581633562 0.298040670993298 GCN1 other 1 1 1 2.98041896667637 -1.04188581633562 7.53784355168366e-05 5628.11379720169 1290.47981937537 4.36125673001679 1.61471060920509e-05 3316.78848612554 2421.71329181983 1.3696041134717 0.171513876251091 RPLP0 essential 0.379379665956238 1 0.139075024770834 4.36125673001679 1.3696041134717 7.61173813212866e-07 740.925287666799 152.455887992061 4.85993225598072 1.6398701038546e-06 12.6203398579998 286.098585055963 0.044111856951446 0.964835390385966 PXN other 0.00465305552017025 1 0.0146290563000268 4.85993225598072 0.044111856951446 5.47956534136707e-08 22.3788828264276 3.84714402954798 5.81701195862351 1.15898433690758e-08 12.3475711138726 7.21954709559982 1.71029719044262 0.0879206964607432 SIRT4 other 0.000358253982018579 1 0.000107681234742084 5.81701195862351 1.71029719044262 0.00608332373017758 -688.585737637028 409.44142936091 -1.68176859560067 0.0933265046936094 -2330.11696839421 725.328962508956 -3.21249679639731 0.00141295012016558 RPH3A other 1 1 1 -1.68176859560067 -3.21249679639731 0.0104133270775614 1342.67219419747 982.85041993799 1.36610023962973 0.172611695029462 -3514.02396811684 1931.71596874203 -1.81912042193514 0.0695788428462958 PEBP1 other 1 1 1 1.36610023962973 -1.81912042193514 0.159848937176847 68.6921728311277 41.1431444860327 1.6695897625046 0.0957183257001571 -3.4894996795236 81.581134993332 -0.042773365188028 0.965901777217295 TBX5 other 1 1 1 1.6695897625046 -0.042773365188028 4.40601117181583e-12 16.0544083749527 36.5155708627824 0.439659246606925 0.660400769155126 -363.483480599306 61.8616975875761 -5.87574371176495 8.34263160806928e-09 BRAP other 3.34768728834567e-08 7.71276292166005e-05 1 0.439659246606925 -5.87574371176495 1.15507868132001e-06 567.468728039353 121.950905187508 4.6532555635141 4.3352962841172e-06 97.7629254090993 209.421329215532 0.46682410896401 0.640857843367534 ERP29 other 0.00695819397627173 1 0.0381809543742202 4.6532555635141 0.46682410896401 0.3103307119807 110.538390791784 81.3971771268268 1.35801258340386 0.175162024700344 -4.62305026801561 159.9798134861 -0.0288977100752608 0.976959394445535 NOS1 other 1 1 1 1.35801258340386 -0.0288977100752608 1.97354470985391e-08 41.1734093405034 73.2472284410152 0.562115594225653 0.574326125850071 -269.013483231657 96.7195277028427 -2.78137713883554 0.00564756361587033 FXYD5 other 0.000132839294420267 1 1 0.562115594225653 -2.78137713883554 2.79864522948148e-61 302.012390317035 61.274710852582 4.92882603793321 1.17746703717858e-06 -497.385731293267 80.8969986461581 -6.14838300081839 1.77021779890222e-09 ZNF302 other 2.7127268209364e-57 1.65196724993555e-05 0.0105312651805252 4.92882603793321 -6.14838300081839 1.54881343800317e-40 245.910233988662 70.0212329065955 3.51193807622172 0.0004912542733942 -456.187944759376 92.4597519938981 -4.93390837550032 1.14880416525875e-06 GRAMD1A other 1.44798568318917e-36 0.0101083278501118 1 3.51193807622172 -4.93390837550032 2.01312321044883e-05 16.8778442857296 3.75400077054605 4.49596185971868 8.87872374805757e-06 2.42488587164086 8.66412384692471 0.279876640094608 0.779704274320417 CMTM1 other 0.108527472275297 1 0.0773070476743373 4.49596185971868 0.279876640094608 0.432959806030504 -6.93394838882206 6.12118572643253 -1.13277863125111 0.257926935944419 -12.0385746757587 13.4069378455675 -0.897936189041023 0.369712886890224 KCNH4 other 1 1 1 -1.13277863125111 -0.897936189041023 5.43177906168746e-10 565.164129364073 85.0505390100062 6.64503877274172 9.02406000427387e-11 419.132119765181 239.019432506009 1.75354830095098 0.080207386028934 BIRC5 other 3.90979456860264e-06 1 8.58729550006701e-07 6.64503877274172 1.75354830095098 1.17232871570722e-09 13.2198119874086 8.60995508088071 1.53541009949802 0.125405138435144 -24.6359763921811 10.0942411751403 -2.44059716473325 0.0150583063679704 OTUB2 other 8.32705086766838e-06 1 1 1.53541009949802 -2.44059716473325 2.55607456291561e-23 39.3095997772715 302.631025252094 0.129892828220525 0.896710848904173 -2186.28257564404 354.802147894845 -6.16197672031005 1.63008827755258e-09 DDX24 essential 2.24218860658957e-19 1.5221764335786e-05 1 0.129892828220525 -6.16197672031005 3.28558793844161e-32 21.8449876074451 36.6895569881656 0.595400691659791 0.551883164772951 -261.87393118931 41.7190014927411 -6.27709009849804 8.30795512128041e-10 ZBTB25 other 2.99744187624029e-28 7.78870792620039e-06 1 0.595400691659791 -6.27709009849804 0.0326233507287529 -53.1597820109303 36.7944006640206 -1.44477912539863 0.149234934589047 -247.765382117812 97.6541321372297 -2.53717253633094 0.0115210909922274 ANKRD24 other 1 1 1 -1.44477912539863 -2.53717253633094 2.4699352406177e-12 77.9191248216926 36.8573603961778 2.1140723042601 0.035076273105196 -82.4395005386103 42.8005686885577 -1.92613096191522 0.0547378453128424 DHX32 other 1.8865365367838e-08 1 1 2.1140723042601 -1.92613096191522 1.99299363372579e-13 18.2431804991281 51.3977303839413 0.354941363419192 0.722805938110548 -266.5713489324 60.3515883126799 -4.4169732128888 1.26541972217408e-05 RCOR1 essential 1.55852102157357e-09 0.106598957395945 1 0.354941363419192 -4.4169732128888 1.47136650004104e-15 -99.7643955608926 146.271903525026 -0.682047564546963 0.4955693833165 -875.381302045083 168.663192656794 -5.19011461988843 3.22216950048742e-07 GPATCH2L other 1.1937196414833e-11 0.00288770830633683 1 -0.682047564546963 -5.19011461988843 1.07893648160052e-12 685.100522823877 316.979615840763 2.16133936880043 0.0312153291969103 -1037.01861245193 432.953036774588 -2.39522193949142 0.0170332537953911 LTBP4 other 8.30349516239758e-09 1 1 2.16133936880043 -2.39522193949142 7.2124508939722e-32 166.43558081134 50.0517928667232 3.32526711389782 0.000958354930106289 -302.423646934738 68.3450149430404 -4.42495545851854 1.22147234778275e-05 BLVRB other 6.57198525458747e-28 0.102982333641564 1 3.32526711389782 -4.42495545851854 0.000236387011644122 16.4100388279086 65.3932186748949 0.25094404527619 0.801975861197302 -165.578572100333 83.6629705873946 -1.9791141880071 0.0484332835022128 SLC9A1 other 1 1 1 0.25094404527619 -1.9791141880071 0.00426147381247633 100.125089595031 63.0848721212043 1.58714896659632 0.113202171060573 -269.937280492176 130.496647721395 -2.06853804450579 0.0391770852077971 SPTLC1 essential 1 1 1 1.58714896659632 -2.06853804450579 3.90020986461394e-16 423.352808101247 204.786718141108 2.06728645267676 0.0392953826732563 -854.297461951792 244.099321201147 -3.49979450064845 0.000513424480625261 PAPOLA other 3.19271179517297e-12 1 1 2.06728645267676 -3.49979450064845 1.04846621521328e-35 125.250298715118 65.5424402319484 1.91098009582598 0.056659632061371 -526.008249447582 77.5872956333518 -6.77956674676866 3.91086970075339e-11 CCNK essential 9.67839163263381e-32 3.71337078086535e-07 1 1.91098009582598 -6.77956674676866 0.00134247675480842 226.685563753198 443.780204318161 0.510805938497156 0.609745487875027 -1758.69248477405 678.147928777615 -2.59337588473382 0.00982357276335 PCBP4 other 1 1 1 0.510805938497156 -2.59337588473382 4.70633386527131e-20 715.557600999585 160.537397313092 4.45726424481675 1.05749646377462e-05 -195.709745939191 205.388812811846 -0.952874420275646 0.341182869756519 NUDC essential 4.02250355464739e-16 1 0.0917378182324484 4.45726424481675 -0.952874420275646 4.9193981371073e-10 181.447548147547 60.2181410153732 3.01317086658694 0.00273597110005291 -282.980593826288 93.6157114620178 -3.02278954469198 0.002652240547839 MAEA other 3.5488538161092e-06 1 1 3.01317086658694 -3.02278954469198 1.43859290143664e-51 1017.81029886757 145.462327478046 6.99707145151504 9.90419504551406e-12 -212.987216406583 176.605511146954 -1.20600549225984 0.228469404926333 STRN4 other 1.37730884383544e-47 1 9.48722843409791e-08 6.99707145151504 -1.20600549225984 0.443246432119675 -12.4043445300286 153.293554267946 -0.0809188917907579 0.935543586243767 252.719115495364 249.523979869035 1.01280492411193 0.311715062071681 LYZ other 1 1 1 -0.0809188917907579 1.01280492411193 8.06212657035233e-51 101.016463119528 40.7321046402202 2.48002071122495 0.0135141109275146 -369.502758823789 52.0914718660068 -7.09334456461988 5.32414079716246e-12 MUL1 other 7.70578057594276e-47 5.09200825840618e-08 1 2.48002071122495 -7.09334456461988 5.56250917458908e-10 88.0656082185377 30.6204902457981 2.87603521405482 0.00422493365910013 -172.265071211768 52.6242450822177 -3.27349249272136 0.00114704190799717 PDCD7 essential 4.00166910019939e-06 1 1 2.87603521405482 -3.27349249272136 3.24388617945504e-13 262.603081951899 88.6140219633843 2.96344840391522 0.00320913138963447 -642.301704412801 152.291683512875 -4.21757570470682 3.00617351443501e-05 SPG21 other 2.52536539070575e-09 0.248460240968053 1 2.96344840391522 -4.21757570470682 3.53290951403657e-06 278.810291961078 57.9916881794041 4.80776298662915 2.10322421421614e-06 -14.7083055592561 162.876881492763 -0.0903032119994858 0.928087642293598 DNAJB11 other 0.0205050068194683 1 0.0186955600401672 4.80776298662915 -0.0903032119994858 0.883549302458074 0.0246419220698304 54.5792573503066 0.000451488775519074 0.99963997201709 -47.096077827404 107.480626975048 -0.438182016172434 0.661472860336007 P3H2 other 1 1 1 0.000451488775519074 -0.438182016172434 1.49080685779464e-32 74.4253685064162 16.6183271771299 4.4785114478213 9.60155048724017e-06 -35.5052393900364 20.2775765500216 -1.75096068814982 0.0806527067133605 FLT3LG other 1.36289562939586e-28 1 0.0834278721836298 4.4785114478213 -1.75096068814982 0.00031554724555281 113.468095312331 39.7550115846347 2.85418342969836 0.00452043323226793 -127.444317595845 71.3106051897012 -1.78717200978475 0.0746042249849272 ZNF268 other 1 1 1 2.85418342969836 -1.78717200978475 0.000332126782987035 220.967646889941 59.5742746943867 3.70911182760503 0.000234786727524545 -32.1707806376532 106.85700596751 -0.301063840843854 0.763509006704684 GOLGA3 other 1 1 1 3.70911182760503 -0.301063840843854 9.13696468881709e-67 180.18845844694 94.6961005668696 1.90280758519407 0.057721119183397 -1162.92035423026 121.599019605848 -9.5635668609809 8.33088607489439e-20 PABPC4 other 8.89940360690785e-63 8.16760070782646e-16 1 1.90280758519407 -9.5635668609809 2.10942392218181e-64 113.889785329094 43.8488845540279 2.5973245725046 0.00971308094390681 -487.132295408551 56.3487559745808 -8.64495208427137 1.03526524071074e-16 USP48 other 2.05057099475294e-60 1.0100047688374e-12 1 2.5973245725046 -8.64495208427137 0.0170994997742158 -99.8143717232686 183.069376345363 -0.545227026583448 0.585874910779668 -1238.66136685386 436.918111252354 -2.83499661596413 0.00479472269383566 PDPR other 1 1 1 -0.545227026583448 -2.83499661596413 2.91582225731663e-05 806.070800728086 325.700954821922 2.47488006649783 0.0137056433209839 -2226.18956424336 777.326327618129 -2.86390603939122 0.00438556502563656 AARS essential 0.154684370750647 1 1 2.47488006649783 -2.86390603939122 0.00500674038493218 364.781847969244 266.972751018611 1.36636359545104 0.172525906473466 -1418.0572230134 616.165291368064 -2.301423405179 0.0218363142353686 GLG1 other 1 1 1 1.36636359545104 -2.301423405179 2.02566358947542e-30 225.076823429558 65.3002287596166 3.44679992252572 0.000622046423410132 -400.887465042166 92.4024763511846 -4.33849265596037 1.78274621475997e-05 PLEKHG2 other 1.83606147750052e-26 0.148966273705343 1 3.44679992252572 -4.33849265596037 0.707555562384897 547.184938812046 832.480641433038 0.657294490199938 0.511336821367417 983.367961047236 1182.47172277785 0.831620699340801 0.406076216384377 DLL3 other 1 1 1 0.657294490199938 0.831620699340801 2.05121381023667e-54 568.209573891913 71.6825896546658 7.92674450838467 1.91814609135943e-14 -37.7455061771747 88.750569384711 -0.425298749505004 0.670829703200463 NAT14 other 1.97244719992358e-50 1 1.85791630409074e-10 7.92674450838467 -0.425298749505004 0.044271452133451 177.427075957362 71.7560632939765 2.47264228014381 0.0137931601183327 100.149190796062 146.447902720041 0.683855411623843 0.494430590977398 PITPNM2 other 1 1 1 2.47264228014381 0.683855411623843 1.50255495174473e-08 181.819436861394 59.6639070811156 3.0473940738444 0.0024526761778799 -307.329677872245 105.40104043357 -2.91581256321603 0.00373585479205254 EXOC1 essential 0.000101722970233118 1 1 3.0473940738444 -2.91581256321603 0.16561203073026 63.2501520866288 39.813244581234 1.58867112569976 0.112857862174773 -25.0543963174759 78.8396699387464 -0.317789208617205 0.750796631720597 RBM27 other 1 1 1 1.58867112569976 -0.317789208617205 3.61194231685473e-05 75.2991803278643 215.952258253107 0.348684384858851 0.727493813390045 -1229.17459016394 351.537286543588 -3.49656960218793 0.000519384607950787 OSBPL8 other 0.189193538556851 1 1 0.348684384858851 -3.49656960218793 0.00333167301200991 -117.520593615391 99.1749785595966 -1.18498229414559 0.236666993349192 -506.455773883285 158.436150007808 -3.19659227933982 0.00149130250314042 WDR7 other 1 1 1 -1.18498229414559 -3.19659227933982 2.30557918254488e-22 4.38546645423724 74.7629139845262 0.0586583136011112 0.95325101501544 -958.884404319352 119.436862272224 -8.02837906218466 9.18295488521371e-15 TXNL1 other 2.01069560509739e-18 8.90562964768026e-11 1 0.0586583136011112 -8.02837906218466 0.494328327727939 108.690582072397 108.176174096476 1.00475527980368 0.315571993084582 -12.7245378657969 201.048195888027 -0.0632909825904821 0.949563801465369 CMTM6 other 1 1 1 1.00475527980368 -0.0632909825904821 0.000754711228999408 181.295073230428 58.2689500416682 3.11134957984971 0.00198497871759968 -149.792980932454 122.099352945337 -1.22681224199047 0.220556756754251 FH ts 1 1 1 3.11134957984971 -1.22681224199047 0.855525793726184 92.3047939147351 167.117623731079 0.552334289190645 0.581002365540253 64.212335632998 272.072924807914 0.2360114872817 0.813534582554596 SEL1L3 other 1 1 1 0.552334289190645 0.2360114872817 0.182514990902176 -1090.14713216956 2006.12566370468 -0.543409195093196 0.587125815234158 -7755.00249376553 4229.64355874951 -1.83348842190813 0.0674115021487386 TF other 1 1 1 -0.543409195093196 -1.83348842190813 9.23593042350333e-06 142.089121282819 158.249750073742 0.89787896168308 0.369745626359915 -1335.45159681441 333.648109977848 -4.00257503902261 7.36257715032662e-05 CDV3 other 0.0515641995544191 0.591583074028744 1 0.89787896168308 -4.00257503902261 0.00210711710382736 -5.02457136124851 4.48266606252006 -1.12088906270743 0.262949269775628 -10.9100413045588 3.32706445364505 -3.27917942575654 0.00112413905598631 MYO15A other 1 1 1 -1.12088906270743 -3.27917942575654 0.689070441606563 -52.1574666999323 74.3433519342784 -0.7015753977039 0.483316596054941 -25.3748423357866 55.1781284029686 -0.459871385097967 0.645836726060468 ALKBH5 other 1 1 1 -0.7015753977039 -0.459871385097967 0.0286158411412565 1171.97411530937 541.399130570023 2.16471370036268 0.0309491157178004 582.363503066524 398.007970524822 1.46319557947195 0.144131091437356 NLRP1 other 1 1 1 2.16471370036268 1.46319557947195 0.0924747165915241 -110.132187032761 132.757673889395 -0.829573039404981 0.407232110688045 -197.866929454941 99.2365445936668 -1.99389176905671 0.0467834879729584 PITPNM3 other 1 1 1 -0.829573039404981 -1.99389176905671 0.00192658339473232 179.653357497271 70.7150080149233 2.54052658043054 0.0114127954779203 -136.357715816898 51.534521621022 -2.64594899744398 0.00843943280130323 SPAG7 other 1 1 1 2.54052658043054 -2.64594899744398 0.557787799963563 -14.4991172983749 22.0790014370023 -0.656692619897011 0.511725034698994 -29.6387001305799 27.4915149562503 -1.07810355950724 0.281583643529807 SLC17A6 other 1 1 1 -0.656692619897011 -1.07810355950724 0.80727521036964 2.82644038790653 4.31859648270112 0.654481241585855 0.513145321529311 2.9020726373836 5.69305469207202 0.509756676222511 0.610478689122583 ESR1 other 1 1 1 0.654481241585855 0.509756676222511 5.64978466539515e-06 -22.4517969195654 42.7368687530531 -0.525349600348563 0.599606018968499 -200.243344742344 56.3385192744051 -3.55428838601578 0.000420227427943945 RGS17 other 0.0321811734540908 1 1 -0.525349600348563 -3.55428838601578 0.000606560370023816 112.530067917061 31.861947243957 3.53180133830032 0.000456641660771475 -65.998875545361 74.7560574520118 -0.882856557647221 0.377799169417116 TMEM101 other 1 1 1 3.53180133830032 -0.882856557647221 0.032597361890411 -207.282223796038 89.8083377386581 -2.30805100077933 0.0214614047597383 -380.625809388915 173.884003584796 -2.18896391584002 0.0291266604070942 CD200 other 1 1 1 -2.30805100077933 -2.18896391584002 0.22411896991203 -161.356881491978 647.122202706052 -0.249345302660358 0.803210579651014 -2044.42298158642 1252.93711306165 -1.63170438505945 0.103460510588622 CCDC80 other 1 1 1 -0.249345302660358 -1.63170438505945 5.49174094677483e-05 451.848423179192 139.459477407767 3.23999796627682 0.00128639181593053 -44.8829816908227 206.838935062658 -0.216994840343895 0.828313403936033 PSME1 other 0.281232053884339 1 1 3.23999796627682 -0.216994840343895 1.41884977121943e-19 149.380686778543 43.1287951890339 3.46359517171316 0.000585700576503502 -235.415813851973 57.7585413705101 -4.07586147894258 5.44837275906265e-05 PPP2R3C essential 1.206589845445e-15 0.442135449397934 1 3.46359517171316 -4.07586147894258 2.71645210335346e-08 148.014914402238 359.329719987621 0.411919488338835 0.680599946080651 -2308.17816664296 536.286270299001 -4.30400383988212 2.07106969850728e-05 JPH4 other 0.000181181970816111 0.172354420309776 1 0.411919488338835 -4.30400383988212 0.0203564681380671 346.543833619665 299.008110043977 1.15897804099259 0.247098048262766 -522.557827060223 443.031137182032 -1.17950587036395 0.238838528411975 MYH7 other 1 1 1 1.15897804099259 -1.17950587036395 0.605560599850938 -130.26753992016 144.808813178288 -0.899582953972386 0.368837661613571 -198.319058311948 215.954225721224 -0.918338400879261 0.358948304597822 SLC7A8 other 1 1 1 -0.899582953972386 -0.918338400879261 7.83957845567964e-08 196.064301331746 73.2086918566536 2.67815605441564 0.00768190557011513 -189.457576359898 101.194641326679 -1.87220957430232 0.0618452394435908 OSGEP essential 0.000509180620696393 1 1 2.67815605441564 -1.87220957430232 2.22217899361083e-12 -75.4121895986409 620.705517632792 -0.121494311644342 0.903355365346433 -5341.04585090324 919.680309980797 -5.80750266471918 1.22174772435866e-08 SLC22A17 other 1.69974471221292e-08 0.000112694010094843 1 -0.121494311644342 -5.80750266471918 1.36730559482618e-19 178.247849789808 47.9485482946641 3.71748167836906 0.000227314955021673 -314.496995234961 71.1147557083589 -4.42238733863772 1.2328690928067e-05 RNF31 other 1.16330360007811e-15 0.103918535832676 1 3.71748167836906 -4.42238733863772 4.00668482981414e-20 67.5773826959448 48.2244627300564 1.40130918770872 0.161834666992797 -422.02446120315 67.2428427010162 -6.27612462904951 8.40334076894307e-10 SCFD1 essential 3.42771887190599e-16 7.87729163680723e-06 1 1.40130918770872 -6.27612462904951 1.40181008700514e-07 68.5289071149484 29.4620641319066 2.32600495362894 0.020477056280198 -92.4823677769444 41.0810786044133 -2.2512156671322 0.0248703018184027 G2E3 other 0.000895336102570185 1 1 2.32600495362894 -2.2512156671322 6.93281146671789e-13 58.4125317527531 203.504105601808 0.287033677183141 0.774222581833517 -1476.98202345214 277.149807738787 -5.32918292638396 1.58385404965445e-07 HECTD1 essential 5.35767670147958e-09 0.00142911150900321 1 0.287033677183141 -5.32918292638396 7.04380640947836e-08 807.533392963615 385.455772491999 2.09500920882013 0.0367452697601153 -1321.77539256609 532.806387539363 -2.48077992959205 0.0134849067497569 HNRNPC essential 0.000457988292744283 1 1 2.09500920882013 -2.48077992959205 0.519192106300529 -1.02454780361765 2.35181271053098 -0.435641749459859 0.663311774347186 1.49956933677855 3.25085502382295 0.461284593065331 0.644823944517722 RPGRIP1 other 1 1 1 -0.435641749459859 0.461284593065331 1.64309903295174e-20 539.919002186443 218.870471204424 2.46684259971351 0.0140135987569353 -1609.03250513483 302.539469956668 -5.31842177605879 1.67437196972061e-07 SUPT16H essential 1.41043620988577e-16 0.00150978120509708 1 2.46684259971351 -5.31842177605879 2.79363240059196e-38 549.094338022369 73.0436378620386 7.51734653549804 3.18441360940165e-13 -492.870444895634 108.216390222213 -4.55448979478585 6.81624473881292e-06 TOX4 other 2.59724004283035e-34 0.0581766488457683 3.07104848490695e-09 7.51734653549804 -4.55448979478585 1.7841341179408e-16 57.278433515368 14.1239997035848 4.05539753026406 5.9334829538591e-05 -50.4949385199945 18.7234882691363 -2.69687666070377 0.00727177819900642 GEMIN2 other 1.46655824494733e-12 1 0.498709242271858 4.05539753026406 -2.69687666070377 0.0361097200244145 5.3438405205069 5.3078481381898 1.0067809743949 0.314595898289852 -8.9926783094091 7.87232016629043 -1.14231613037235 0.253946695818961 TGM1 other 1 1 1 1.0067809743949 -1.14231613037235 3.83832105868158e-23 169.087508727106 51.5302210378259 3.28132706054155 0.00111581942571667 -429.604536279177 76.4269036506061 -5.6211165932243 3.38255390607892e-08 TINF2 other 3.3631369116168e-19 0.000310011065492133 1 3.28132706054155 -5.6211165932243 0.00164910255666755 72.4057172858499 59.6238577855416 1.21437491593185 0.22526040142199 -168.429985944684 90.9662792509862 -1.85156507808753 0.0647626741744375 TRPM7 essential 1 1 1 1.21437491593185 -1.85156507808753 0.0259406831412673 -259.499221474149 293.43730566764 -0.884342980466393 0.376998494921788 -1138.77518147327 447.719755971902 -2.54349996015082 0.0113191318457786 TYRO3 other 1 1 1 -0.884342980466393 -2.54349996015082 0.00386414911756195 137.385874353356 44.7835953498006 3.06777232333061 0.00229130203528634 62.1159554521427 67.716702284461 0.917291500569669 0.359498191713245 WDR76 other 1 1 1 3.06777232333061 0.917291500569669 0.821487547786464 -116.977872907584 332.574535499057 -0.351734304408029 0.725207848913652 -313.912327467414 502.881705496716 -0.624226978305665 0.532805761886634 CAPN3 other 1 1 1 -0.351734304408029 -0.624226978305665 0.000258078090709895 52.278661305261 67.0730982752616 0.779428155990564 0.436151377028201 -263.671787110037 101.420374843185 -2.59979109244789 0.0096453610936008 SNAP23 essential 1 1 1 0.779428155990564 -2.59979109244789 0.0107624715908508 69.5689434125553 24.4783961810367 2.8420548020401 0.00469320918000699 58.4590297921447 30.7977479837446 1.89815923628572 0.058336770501513 TBX15 other 1 1 1 2.8420548020401 1.89815923628572 9.67264636875555e-13 1307.25212743794 625.749770295405 2.08909725499509 0.0372795531873093 -1593.40999855768 787.293562205422 -2.02390832981551 0.0435903537938252 PHGDH other 7.45180676248928e-09 1 1 2.08909725499509 -2.02390832981551 0.000268551423796365 -923.04484428634 1016.20646515358 -0.908324121070062 0.364206499343124 -4303.858784402 1334.86429031423 -3.22419201384799 0.00135778374115226 EZR other 1 1 1 -0.908324121070062 -3.22419201384799 0.0666396695184373 2317.79390651088 992.990135625834 2.33415602366491 0.0200409379658418 2274.90626043406 1581.34426621108 1.4385901343828 0.150984117764621 MYL6 other 1 1 1 2.33415602366491 1.4385901343828 3.24855959549423e-57 125.318263487209 80.419353491762 1.55830976059819 0.119882064500196 -902.475668997498 103.266285342225 -8.73930601848112 5.03600561443816e-17 AGO1 other 3.13421029773283e-53 4.91816308306031e-13 1 1.55830976059819 -8.73930601848112 2.4621286013861e-05 65.7652366467556 31.234340532031 2.10554266639032 0.0358128163198411 -18.0103749117838 40.1079364830675 -0.44904765717347 0.653619374137519 TEKT2 other 0.131502288600032 1 1 2.10554266639032 -0.44904765717347 1.22782854902401e-09 71.7570647291525 20.5925208153613 3.48461780723923 0.000542481372996891 -0.831908742104241 26.4428031077451 -0.0314606866266979 0.974916474744144 CLSPN other 8.71389921242337e-06 1 1 3.48461780723923 -0.0314606866266979 0.758798911023812 62.1006548909282 86.5425743392697 0.717573464448576 0.473402845880326 -0.190310381405404 186.446815638627 -0.00102072207966408 0.999186046471065 RFFL other 1 1 1 0.717573464448576 -0.00102072207966408 7.25875230250782e-17 302.699278125542 55.0985929272927 5.49377510465612 6.70815233698484e-08 -136.398337272431 80.9343479273862 -1.68529605495564 0.092648636790222 NUP50 other 6.00153640371347e-13 1 0.000615674221488468 5.49377510465612 -1.68529605495564 1.18702547575341e-05 133.817845651445 28.3870449849785 4.71404634481177 3.27042577217886e-06 168.963458675504 47.1121497441283 3.58640944200519 0.000373119736746534 CDC45 essential 0.0654881954973157 1 0.0289067756775225 4.71404634481177 3.58640944200519 0.0173036608137902 -245.500935511651 123.254157656754 -1.99182680875835 0.0470105438200314 97.7116796461161 202.766123697823 0.481893512901263 0.630122290350301 ADA2 other 1 1 1 -1.99182680875835 0.481893512901263 4.91503749689495e-21 -1.17836122626406 72.1435849101402 -0.0163335551973442 0.986975725316884 -592.497415425557 93.1469710644231 -6.36088762366486 5.05499544718432e-10 ECHDC1 other 4.24462638231848e-17 4.75422321807685e-06 1 -0.0163335551973442 -6.36088762366486 1.85504557563011e-05 168.694873457783 91.2734152723972 1.84823667389161 0.0652419952720757 -429.825823388468 159.509441115123 -2.69467324556826 0.00731670535131224 LRRFIP2 other 0.100320864730076 1 1 1.84823667389161 -2.69467324556826 4.69918361791504e-17 13.835275008402 74.4466090122043 0.185841574142537 0.852655034500307 -857.39475747732 119.65827658687 -7.16536107600435 3.31201117886013e-12 SEC22C other 3.8937435458044e-13 3.17323791046589e-08 1 0.185841574142537 -7.16536107600435 0.0408514831570496 7.07961178227244 7.70880858757117 0.91837950078133 0.358925662780894 -19.2812617830262 13.1137680687779 -1.47030675560994 0.142196663370694 XYLB other 1 1 1 0.91837950078133 -1.47030675560994 2.83188799960787e-05 118.250501403932 25.6323181885637 4.61333620057399 5.21041978323942e-06 88.9318090653831 56.1412301717831 1.58407303853632 0.113898822256374 CDC6 essential 0.150344933899182 1 0.0457266440177092 4.61333620057399 1.58407303853632 0.00153438592342519 119.045422009884 69.8069346598917 1.70535237781015 0.0888377369748754 -166.932107016681 107.672455453234 -1.55036964945213 0.121775043722739 AAAS other 1 1 1 1.70535237781015 -1.55036964945213 0.445497836379853 58.8916595166599 46.2802632161983 1.27250053098331 0.203870424557768 50.1908158158159 95.7327491545566 0.52428052321766 0.600348652307425 EPB41L4B other 1 1 1 1.27250053098331 0.52428052321766 0.18010339591878 0.361455850404644 29.3811102555891 0.0123023210239608 0.990190017050935 -104.324303167301 61.2168533279217 -1.7041761785511 0.0890573932396093 TMEM38B other 1 1 1 0.0123023210239608 -1.7041761785511 0.000160815298083427 10.8767739164601 35.6943803220198 0.304719505376879 0.760724526989881 -274.200850444258 73.178963247213 -3.74699009492597 0.00020291643487071 PSMD5 other 0.777059520339118 1 1 0.304719505376879 -3.74699009492597 0.581873096705419 -7.29896831851524 109.926446881151 -0.0663986558794781 0.947090736883453 -221.02503205919 225.366103673466 -0.980737690613112 0.327263510322523 PTGS1 other 1 1 1 -0.0663986558794781 -0.980737690613112 9.60416027361886e-09 639.607814761219 108.49627416036 5.89520533964018 7.49205118763033e-09 79.9602026049223 239.806511450465 0.333436327984942 0.738964870234583 NUP188 other 6.5615622989364e-05 1 6.98708693758404e-05 5.89520533964018 0.333436327984942 5.0106050400331e-12 492.663826712832 93.5187013083923 5.26807814715259 2.16890191662677e-07 -572.14874178685 201.619032717672 -2.83777148454051 0.0047544853336708 CRAT other 3.80304922538512e-08 1 0.00197283318336371 5.26807814715259 -2.83777148454051 0.425007511915734 -8.639719664249 31.3525075153957 -0.275567102886634 0.783010536548078 75.702754461739 69.2971693879218 1.09243646068657 0.275241807586163 SH2D3C other 1 1 1 -0.275567102886634 1.09243646068657 2.72282847795674e-08 222.830905988336 37.0313582098093 6.01735709303014 3.75450621610204e-09 201.631245287512 78.9032749505427 2.55542302159063 0.0109434722920729 NANS other 0.000181503746340597 1 3.517596873866e-05 6.01735709303014 2.55542302159063 0.294819845592338 12.1849701393499 17.171880478767 0.709588571526373 0.478336875149583 57.4777899215431 36.8225153846289 1.56094143273918 0.119259782970856 TBC1D2 other 1 1 1 0.709588571526373 1.56094143273918 0.843804140931147 10.7928808281956 41.9081362322479 0.257536645590329 0.796885478800902 50.8142277888713 87.3174705332334 0.581948005119219 0.560901106429438 WHRN other 1 1 1 0.257536645590329 0.581948005119219 3.64866500281796e-35 99.5243992323442 27.8654960273008 3.5715997710874 0.000394323609214561 -152.604062631177 33.6130814385385 -4.54002001899807 7.28687522439885e-06 CWF19L1 other 3.36297453309731e-31 0.0621133244127758 1 3.5715997710874 -4.54002001899807 5.86510039009919e-40 28.424913340043 38.7997164909058 0.732606212385739 0.46419049897468 -361.469827425547 46.7297768493343 -7.73532106928298 7.16401754559347e-14 SEMA4G other 5.47624423423561e-36 6.92259015430697e-10 1 0.732606212385739 -7.73532106928298 5.89614948868209e-10 74.4014413808834 127.198789772486 0.5849225571561 0.55890098000908 -501.787942169638 153.5971610491 -3.26690896330586 0.00117278708539534 BTAF1 other 4.23815225246469e-06 1 1 0.5849225571561 -3.26690896330586 1.43629447392368e-42 98.9399467240911 53.7030083450974 1.84235389735152 0.066099117005119 -398.662791202321 62.3433931160751 -6.39462774283176 4.13243844524668e-10 IKZF5 other 1.34954228769869e-38 3.88945106466617e-06 1 1.84235389735152 -6.39462774283176 0.038389632304794 3.46827376064572 35.719201718208 0.0970982999006316 0.922692745036796 73.6951265415662 45.1321394154945 1.63287465420409 0.103213989961694 BLNK other 1 1 1 0.0970982999006316 1.63287465420409 0.750579886217461 -8.08924025161889 10.7131877373486 -0.755073135087325 0.450610917571671 -7.59524163359097 13.5363910526565 -0.561097976857017 0.575017684587201 TLL2 other 1 1 1 -0.755073135087325 -0.561097976857017 5.99033962478993e-08 236.239191047143 814.31235615071 0.290108812991438 0.771870288323546 -3453.82937199825 1030.627473291 -3.35119086333831 0.000874384058992927 SORBS1 other 0.000390809757121295 1 1 0.290108812991438 -3.35119086333831 1.8029665652328e-17 -84.7993591667946 390.596590420108 -0.217102148985961 0.828229829346149 -2510.41058980393 471.034621911888 -5.32956702760911 1.57907348154364e-07 CRTAC1 other 1.49988788561717e-13 0.00142495590974498 1 -0.217102148985961 -5.32956702760911 4.9900371571648e-08 181.585098319929 37.3949019773325 4.85587844113082 1.67202231711906e-06 3.70935809737426 73.3363974701252 0.0505800424527988 0.959683276663697 BAMBI other 0.000327196736395296 1 0.0149094230017507 4.85587844113082 0.0505800424527988 0.915818661620492 -7.12107804863948 20.2350328668372 -0.351918284269756 0.725069961719917 -0.670566528183579 39.4754151206398 -0.0169869405080169 0.98645482254857 MYO3A other 1 1 1 -0.351918284269756 -0.0169869405080169 1.80417085276527e-49 687.054423344144 117.123929671997 5.86604654803014 8.82054468733053e-09 -2239.89940629078 229.695669877546 -9.75159613363587 1.85241851361693e-20 WAC essential 1.72081815936751e-45 1.81740780370957e-16 8.21898353965458e-05 5.86604654803014 -9.75159613363587 2.42260364557885e-05 93.0151745068277 27.285748785081 3.40892878694557 0.000713692205116283 228.384420839655 49.7261019246153 4.59284786058407 5.7510020235643e-06 CREM other 0.129488164856189 0.0492573323318283 1 3.40892878694557 4.59284786058407 0.131452069959792 -1.58326723166199 2.9166344845028 -0.542840469066144 0.587515762627979 13.3820398279965 8.06487127506554 1.65929986624464 0.097771187031686 SMIM24 other 1 1 1 -0.542840469066144 1.65929986624464 0.0117841499104746 2.0421832320571 41.3700264378945 0.0493638367653177 0.960652004079424 -186.391286403943 73.2598244935702 -2.54424969882779 0.0112960215692291 HIVEP1 other 1 1 1 0.0493638367653177 -2.54424969882779 0.000266169902264113 368.729691876752 189.49837953151 1.94581976261934 0.0523156594473531 1799.79857071033 441.68935934025 4.07480626972468 5.4680152777204e-05 TREM2 other 1 0.443456039023124 1 1.94581976261934 4.07480626972468 0.0122856271956762 -361.523429879988 387.029007577869 -0.934099054079948 0.350767464233221 2053.63809140127 908.656703629925 2.26008137418383 0.0243065574946196 FKBP5 other 1 1 1 -0.934099054079948 2.26008137418383 6.91902835592818e-07 161.773928162503 49.8447979370575 3.24555289333877 0.00126213847298117 -323.644346437104 117.024328667339 -2.76561592040505 0.00592169556260056 SRPK1 other 0.00423998057651279 1 1 3.24555289333877 -2.76561592040505 0.00011035266747857 -78.106674865357 108.770173344816 -0.718089090634692 0.473085198275369 -1073.95167012991 255.367802489252 -4.20550930720842 3.16038126476898e-05 BRPF3 other 0.544369708671783 0.260763058156088 1 -0.718089090634692 -4.20550930720842 0.317914055655986 10.2626515763987 47.5093748936597 0.216013188962592 0.829078258454434 138.601535974134 96.0125812977362 1.44357681150483 0.149574525600921 MRPS18A essential 1 1 1 0.216013188962592 1.44357681150483 0.537824587168902 -3.785649365005 43.2336613159066 -0.0875625438554328 0.930264667014651 93.5291540773134 96.9773959452112 0.964442828823266 0.335359798685549 TMEM14A other 1 1 1 -0.0875625438554328 0.964442828823266 0.272101933058735 90.0211000958414 85.6680934747159 1.05081246056223 0.293925470063792 304.268967305066 195.220870077308 1.55858831683608 0.119817729040242 EFHC1 other 1 1 1 1.05081246056223 1.55858831683608 0.000777470885689611 1214.61305484087 1423.91995425427 0.853006555046828 0.39412402128718 -8546.38376451045 2877.69577310175 -2.96987049305029 0.00314373922148528 HSP90AB1 other 1 1 1 0.853006555046828 -2.96987049305029 7.12075182423741e-14 372.04577500456 73.9346132909662 5.03209198566295 7.1072261209599e-07 -516.470229533439 149.419441393216 -3.45651291905371 0.000600883672304773 CDC5L essential 5.61827318932331e-10 1 0.00639792495408811 5.03209198566295 -3.45651291905371 0.463077957329215 -44.6701146330733 36.2034789271655 -1.23386248937405 0.217917321996218 -28.9278052512983 84.9993105120372 -0.340329881231233 0.733771650434333 ITPR3 other 1 1 1 -1.23386248937405 -0.340329881231233 2.30614960412885e-06 69.2241212706849 18.746866536032 3.69257022967728 0.000250238519552133 -72.4140194065308 39.879030992306 -1.81584200028586 0.0700829170610521 ZNF184 other 0.0135878334675272 1 1 3.69257022967728 -1.81584200028586 0.572340621729527 -25.6958831921273 30.7289813892012 -0.836210054172422 0.403494788583702 -54.0759600547357 54.9132842067049 -0.984751883554854 0.325292103597952 DSP other 1 1 1 -0.836210054172422 -0.984751883554854 5.56070587588707e-29 63.7806597124359 62.3262132350036 1.02333603153377 0.306713846944858 -489.732636418282 75.6759029162323 -6.47144754863884 2.603745227002e-10 SIRT1 other 5.01297634711219e-25 2.45507137454019e-06 1 1.02333603153377 -6.47144754863884 9.31351481347975e-26 499.22103185792 234.49175823458 2.12894916058632 0.0338157774084855 -1423.14401916515 284.717691156801 -4.99843902703393 8.37240126935726e-07 HNRNPH3 other 8.27598926325811e-22 0.00740622616287343 1 2.12894916058632 -4.99843902703393 8.04247511434988e-09 58.1787842370465 17.4877999636424 3.32682123297394 0.000956284441381617 -32.9346475567784 19.8979368939275 -1.6551790133996 0.0986405533773975 IFT74 other 5.51891765426496e-05 1 1 3.32682123297394 -1.6551790133996 0.0100520683286051 53.7251985035738 27.9358992634448 1.92315980226473 0.0551109307475098 -13.2722201255328 32.1650830233191 -0.412628194241274 0.680081865561668 JAK2 og 1 1 1 1.92315980226473 -0.412628194241274 5.1005088220637e-05 628.194148006776 192.991472449181 3.25503577973992 0.00122191746588193 -683.333926507356 418.768911795948 -1.63176851781281 0.103448632967219 ABL1 og 0.261911128012971 1 1 3.25503577973992 -1.63176851781281 0.0311780558197443 77.1348538223278 131.449688486002 0.58680134362237 0.557640840035693 309.14934919807 167.379943529956 1.84699159695165 0.0654257259398584 ACOT7 other 1 1 1 0.58680134362237 1.84699159695165 2.10688694688635e-56 306.510443321008 160.652098099834 1.90791434999207 0.0570559003449218 -1736.45785981414 207.285687016909 -8.37712378893046 7.42341395075055e-16 SH3GLB1 other 2.03082832810375e-52 7.22892050524088e-12 1 1.90791434999207 -8.37712378893046 2.23416326555587e-12 216.604681839999 43.7654017117691 4.94922183661235 1.06477190664752e-06 62.3084099079035 56.4694857315682 1.10339963434573 0.270459503802555 CDC7 essential 1.70868806549713e-08 1 0.00953929151165516 4.94922183661235 1.10339963434573 0.0138451617493763 -3.63726185913041 4.68412919010248 -0.776507587966598 0.437868463422473 -13.1722876026893 6.0438235711243 -2.17946262786737 0.0298293544456509 SYDE2 other 1 1 1 -0.776507587966598 -2.17946262786737 0.530141599603906 10.7397290156821 32.1082100112519 0.334485448174113 0.738174111354864 -55.6493281948117 66.9797181661451 -0.83083849437485 0.406519610542338 PCSK5 other 1 1 1 0.334485448174113 -0.83083849437485 1.56164852833758e-14 -15689.7305197126 5398.82029288699 -2.90614053969975 0.00384559150704327 -43970.4007780459 6512.39030516633 -6.75180674339556 4.67549697974601e-11 SCD essential 1.24619552561339e-10 4.43751418347694e-07 1 -2.90614053969975 -6.75180674339556 1.08476131807681e-15 -266.656834112162 722.586339060565 -0.369031103547907 0.712282864037065 -3829.4167640187 825.908942014354 -4.63660891560143 4.68153024768449e-06 ABLIM1 other 8.82019427728251e-12 0.0402611601300866 1 -0.369031103547907 -4.63660891560143 0.121056265828167 28.2450415619561 71.6015362751152 0.394475356693883 0.693423000307592 -99.0873767639669 82.4688608227943 -1.2015126167061 0.230204657453244 ERMP1 other 1 1 1 0.394475356693883 -1.2015126167061 5.92612384543146e-43 668.317360730981 100.327934277004 6.66132882678284 8.18007285183063e-11 -1518.06397589946 196.756479531754 -7.71544591320288 8.25172852989738e-14 RAB18 other 5.576482538551e-39 7.97116975988087e-10 7.78742935494276e-07 6.66132882678284 -7.71544591320288 1.5163224998152e-05 -1.87698764487235 84.0292427156883 -0.022337314775323 0.982189102402889 611.343972725248 158.607740139369 3.8544397151618 0.000133445013120534 NRP1 other 0.0828366981649041 1 1 -0.022337314775323 3.8544397151618 9.25915800495747e-24 399.016092652034 51.7527584297347 7.71004492820963 8.63467996742546e-14 -192.437596994497 100.961616227475 -1.90604711161634 0.0573029002396548 PRTFDC1 other 8.14065171795861e-20 1 8.34628165651345e-10 7.71004492820963 -1.90604711161634 0.000378896765875688 21.3294755330172 63.2587013340391 0.337178523795271 0.736143838575302 -151.749812494964 81.6167361598898 -1.85929773273072 0.0636553017657686 PALMD other 1 1 1 0.337178523795271 -1.85929773273072 0.00849395231595454 -42.4326684336206 150.161628228795 -0.282579970223603 0.777632628849544 -376.737009626489 182.347952443239 -2.06603367122403 0.0394140972155522 TSPAN15 other 1 1 1 -0.282579970223603 -2.06603367122403 1.50737234338856e-28 229.589866533885 108.68595988822 2.11241513411679 0.0352188477197977 -719.364782883222 131.999017433924 -5.44977377004583 8.45288972785397e-08 H2AFY2 other 1.35663510904971e-24 0.000768621262953762 1 2.11241513411679 -5.44977377004583 5.03696834976125e-37 204.842531154776 73.8847930642036 2.77245861644053 0.0058029639090804 -642.584917179442 96.533048901614 -6.65663132461879 8.48115274508470e-11 WASHC2A other 4.66775856972375e-33 8.02656295794816e-07 1 2.77245861644053 -6.65663132461879 1.87488447759333e-24 235.543813122141 57.7139791121584 4.08122636396975 5.33072069562924e-05 -85.8561538931723 71.6789239761899 -1.19778798467583 0.231651804521956 MZF1 other 1.65458555147611e-20 1 0.448899989778939 4.08122636396975 -1.19778798467583 5.40158714681807e-10 -10.5480670855089 10.3487325575751 -1.0192617334369 0.308641380817454 -66.7621920258281 14.3861550082735 -4.64072519637338 4.59352175338372e-06 KCNK6 other 3.88860258699433e-06 0.0395226611661136 1 -1.0192617334369 -4.64072519637338 3.64034189393968e-20 10.5601579374162 4.54514580390501 2.32339255835166 0.0206150712244143 -23.2224037710969 6.31837490305217 -3.67537604643862 0.000266949564072112 CATSPERG other 3.11576862702297e-16 1 1 2.32339255835166 -3.67537604643862 2.01202155021108e-50 676.879214253775 92.0937991843099 7.3498891374773 9.80480292162652e-13 -386.906198513085 128.022988611925 -3.0221619000468 0.00265694618011963 PSMD8 other 1.92188298476162e-46 1 9.44104473323417e-09 7.3498891374773 -3.0221619000468 1.13958165495804e-13 665.701214784187 86.2259367331245 7.72042891044003 8.13778335483687e-14 -90.9758350691011 248.481406557003 -0.36612733455463 0.714449291874405 CDC34 other 8.96622846120989e-10 1 7.86679516912081e-10 7.72042891044003 -0.36612733455463 5.3594595274114e-15 220.335814416083 36.4552157728267 6.04401344897042 3.41972474216016e-09 -21.2873454443547 43.0494820896145 -0.494485517852261 0.621232107930403 MTAP other 4.30739762218054e-11 1 3.20667589072358e-05 6.04401344897042 -0.494485517852261 0.000305722843587307 -255.554373041001 222.199841017946 -1.15011051254695 0.250737578898607 -868.557297666767 260.132095147999 -3.33890863091158 0.000914329355262618 CEP170B other 1 1 1 -1.15011051254695 -3.33890863091158 1.10440573275645e-12 329.836476138686 45.3619079886131 7.27122140059635 1.6739350314674e-12 -106.347406634429 132.609979804524 -0.801956284068456 0.423017128712628 POLRMT essential 8.49729770782814e-09 1 1.60999071326535e-08 7.27122140059635 -0.801956284068456 0.171353899743129 -149.377379486342 88.6602083742425 -1.68483000689337 0.0927402671325537 118.153462217541 257.976991834921 0.457999999833889 0.647181663899211 HCN2 other 1 1 1 -1.68483000689337 0.457999999833889 0.402720047788234 -0.50152650369583 12.8471849200127 -0.0390378520133681 0.968877996861002 -12.5031475907581 14.910693360185 -0.838535625992039 0.402187326630777 RASSF7 other 1 1 1 -0.0390378520133681 -0.838535625992039 0.769251539066117 63.1698143429185 197.023210387033 0.320621180716869 0.748651803801944 -327.535842737531 578.634485638318 -0.566049640778342 0.571652594011561 PALM other 1 1 1 0.320621180716869 -0.566049640778342 0.235171644967816 -5.10390281726546 10.5728839556607 -0.482735158984966 0.629528321057042 -51.7985373937632 30.4683854557336 -1.70007490121258 0.0898366059196567 MADCAM1 other 1 1 1 -0.482735158984966 -1.70007490121258 0.492176081160218 -8.21752318261787 23.6421983829356 -0.347578640933369 0.728323994520524 11.1816315825101 27.2921616977754 0.409701206754226 0.682225897996073 IGF2-AS other 1 1 1 -0.347578640933369 0.409701206754226 4.12737318028465e-05 221.322973600888 97.3268662285607 2.27401725933657 0.0234479910692864 -302.057393684202 161.513736437332 -1.8701653515483 0.0621276420531427 ARVCF other 0.214912321497422 1 1 2.27401725933657 -1.8701653515483 2.7197854841464e-08 191.52539519423 58.0520636493729 3.29920046169279 0.00104894946921126 -215.684370002244 97.2310355413882 -2.21826671701377 0.0270499634793725 TRMT2A other 0.00018132809822804 1 1 3.29920046169279 -2.21826671701377 2.35641650725982e-10 350.895605612027 70.3219831264697 4.98984229413672 8.73978937802178e-07 -110.702603127185 117.78184634414 -0.939895294252138 0.347790495592739 RANBP1 other 1.71335044242862e-06 1 0.00785270075615257 4.98984229413672 -0.939895294252138 1.32526109995769e-06 187.249679482948 58.7572863008729 3.186833349044 0.00154158813313439 -158.473796904528 98.4122085158191 -1.61030627494814 0.108053062625068 ZDHHC8 other 0.00794494029424637 1 1 3.186833349044 -1.61030627494814 8.43170196677993e-15 129.511777884654 44.5696339623576 2.90582996472523 0.00384933666658208 -361.710310077651 75.377662839125 -4.79864055814032 2.19781643709185e-06 KLHL22 other 6.75632278598076e-11 0.0191473767999442 1 2.90582996472523 -4.79864055814032 3.95684818593322e-11 300.173665392721 89.8789358261901 3.33975544584999 0.000910586005792896 -497.502905319945 152.006276891746 -3.2729102737925 0.0011491506039794 MED15 other 2.94231231105994e-07 1 1 3.33975544584999 -3.2729102737925 8.93255348966371e-09 119.214127642387 42.9079842281977 2.77836700527272 0.00569921881646315 -217.746520890064 72.5674249645216 -3.0006097225652 0.00284896431490145 SNAP29 other 6.11433286367481e-05 1 1 2.77836700527272 -3.0006097225652 7.59365604015205e-13 2284.30523916048 358.336925976106 6.37474140555862 4.67285056816499e-10 26.8761418035751 606.031452083449 0.0443477672836595 0.96464749961272 CRKL other 5.86533992541344e-09 1 4.4181802122e-06 6.37474140555862 0.0443477672836595 1.50855371952033e-11 875.232589902329 124.27951108403 7.04245279264535 7.3977128166511e-12 531.777912037694 210.185685891323 2.53003866453899 0.0117560903822025 LZTR1 other 1.13307469873172e-07 1 7.09366681988674e-08 7.04245279264535 2.53003866453899 0.004373023537176 5.72644977541344 9.42925686323357 0.607306584015325 0.543962173176306 44.7802533186118 14.989397766569 2.98746180573616 0.0029710665565071 MMP11 other 1 1 1 0.607306584015325 2.98746180573616 2.32153738823402e-07 36.0244905798319 79.0059752108229 0.455971722185603 0.648636299842688 -553.074633384756 129.973184248094 -4.25529801846697 2.55505489438174e-05 CECR2 other 0.00146535439945332 0.211890702391078 1 0.455971722185603 -4.25529801846697 6.79218096843408e-14 526.486305237008 127.760219329671 4.1208938744733 4.5143005409974e-05 -639.323476826174 203.096466036859 -3.14788085337805 0.00175695759116558 SMARCB1 other 5.36038922028818e-10 1 0.38136810970346 4.1208938744733 -3.14788085337805 1.39707648454759e-05 115.639680423365 46.4874104989759 2.48754833151896 0.0132354536722287 -153.669253927531 78.6210709698735 -1.95455559218233 0.0512742758061108 P2RX6 other 0.0765597913532081 1 1 2.48754833151896 -1.95455559218233 0.000788602975784736 -5.58152869438666 7.78165851485575 -0.717267235992316 0.473591551302158 32.0678402047626 12.3702616711601 2.59233321470678 0.00985146362226429 DERL3 other 1 1 1 -0.717267235992316 2.59233321470678 0.488146002138679 -5.83981631874139 9.13720125734756 -0.639125280735759 0.523077058809213 -18.5058679761 15.4531418465601 -1.19754727937215 0.231743957168952 SLC7A4 other 1 1 1 -0.639125280735759 -1.19754727937215 4.66037149012574e-15 115.756695723287 79.0448170939402 1.46444384311392 0.143790073625648 -759.784919056561 130.037083253422 -5.84283267547503 1.00253778464177e-08 BCL2L13 other 3.74973490095517e-11 9.2554288278128e-05 1 1.46444384311392 -5.84283267547503 3.52783265460204e-07 201.673471180146 51.3534394002179 3.92716580497022 9.9821861720655e-05 -67.7783869915435 81.6349730436011 -0.830261644789705 0.406843176678906 DDTL other 0.00220066200994075 1 0.829519670898643 3.92716580497022 -0.830261644789705 0.00768258675605517 -36.1939223607946 45.257637353961 -0.799730707940432 0.424300338155976 -210.004610925698 71.9446652173409 -2.91897405167271 0.00369286832786019 GSTT2 other 1 1 1 -0.799730707940432 -2.91897405167271 0.380843872086809 22.0021458410046 18.1372802000602 1.21308959217224 0.22574938671334 36.8583490991275 29.2578728467251 1.25977542154959 0.208421224601882 OSM other 1 1 1 1.21308959217224 1.25977542154959 9.50246577116685e-14 319.003471698116 163.469375420957 1.95145709021421 0.0516411964280212 -1328.50898742138 259.885304299726 -5.11190500363656 4.77854743556431e-07 CABIN1 other 7.48509228794813e-10 0.00426150860303625 1 1.95145709021421 -5.11190500363656 0.000461331968673009 32.3712344461035 143.757134658643 0.225180019920196 0.821944493669297 -713.922645832673 231.919516321133 -3.07832069140798 0.00221279306956413 TBC1D10A other 1 1 1 0.225180019920196 -3.07832069140798 0.0677216813638467 9.23124528301975 23.5894912157058 0.391328714918346 0.695745009917676 78.0399465408812 37.5028171917971 2.08090891256966 0.038024055720952 SUSD2 other 1 1 1 0.391328714918346 2.08090891256966 7.1437356578943e-07 248.81051883627 235.570701496326 1.05620315793028 0.29146028988345 -1430.79821571905 383.283721669878 -3.73300021583331 0.000214277931432012 SF3A1 essential 0.00437339496976289 1 1 1.05620315793028 -3.73300021583331 0.499436280422802 141.847396226411 142.948652032679 0.992296144170589 0.321602197678833 250.2234072327 227.261245949471 1.10103861389696 0.271485939699803 GGT5 other 1 1 1 0.992296144170589 1.10103861389696 4.88639070025485e-08 152.363099859205 45.7974629371853 3.32688952809859 0.000952580803459543 -155.841710857008 74.5144533089419 -2.09142929910359 0.0370677324121365 RNF215 other 0.000320791549471731 1 1 3.32688952809859 -2.09142929910359 0.892448051966116 -139.405104806768 295.039210576789 -0.472496874345065 0.636808589609521 -156.359997763068 480.041558437087 -0.325721794321606 0.744791117222731 SEC14L2 other 1 1 1 -0.472496874345065 -0.325721794321606 1.06993060745343e-08 126.630490566038 81.6775032950668 1.55037171139493 0.121776201159366 -507.754023584904 129.851739774611 -3.91025968898248 0.000106853327417937 SPECC1L other 7.29157708979509e-05 0.84745373975166 1 1.55037171139493 -3.91025968898248 1.69174191214212e-13 260.291053746793 73.7088488080346 3.53134064574374 0.000457519612634315 -466.19582535349 120.993321639825 -3.85307072353356 0.000134168750788254 PPIL2 other 1.32547978816335e-09 1 1 3.53134064574374 -3.85307072353356 2.2459639283594e-09 185.453873110306 47.5278440440044 3.90200474775589 0.00011047298081882 -158.208263721935 78.0171148275597 -2.02786611721826 0.0431815160586984 YPEL1 other 1.57778965967248e-05 1 0.91626290291129 3.90200474775589 -2.02786611721826 1.90029170885613e-15 343.791846292872 56.2046668862776 6.11678469669588 2.12179014983691e-09 -115.792717567686 90.0683227439362 -1.28560979087935 0.19926012372098 SNRPD3 essential 1.53942631334435e-11 1 1.99405838281672e-05 6.11678469669588 -1.28560979087935 1.48532140350798e-08 458.497811320757 160.874431881514 2.85003530988968 0.0045782196777075 -687.187721698108 255.759836213413 -2.68684767660197 0.00748807251318031 PES1 essential 0.000100600818659595 1 1 2.85003530988968 -2.68684767660197 5.18193671285811e-08 133.42369232441 374.699292396253 0.356082050412073 0.721951352432607 -2863.00648574495 615.070140644672 -4.65476422370975 4.31058486742969e-06 MAPK1 other 0.000339572312793592 0.0371141357085696 1 0.356082050412073 -4.65476422370975 0.000489827321705133 56.4498322535083 53.6490006808601 1.05220659354513 0.29328757366896 -222.857103079201 88.0650139027397 -2.53059748931996 0.0117376562375791 PPM1F other 1 1 1 1.05220659354513 -2.53059748931996 0.000965066805749198 28.5692075471681 17.230077005741 1.65810097875064 0.0980146744835896 -47.5206477987435 27.392554686244 -1.73480160368567 0.0834810216640162 SLC35E4 other 1 1 1 1.65810097875064 -1.73480160368567 2.63896637038924e-07 99.6253485723271 33.0852641740589 3.01116980805129 0.00275299094399705 -114.884771480565 53.8222197739437 -2.13452310148275 0.0333545479242579 TOP3B other 0.00165964595033779 1 1 3.01116980805129 -2.13452310148275 0.543425965978035 -31.5514849724345 70.8952179065984 -0.44504390992919 0.656508883656778 57.6332473768456 110.278657681977 0.522614697968569 0.601507858753879 CYTH4 other 1 1 1 -0.44504390992919 0.522614697968569 0.0168075970716105 23.3676401459658 27.0056518544655 0.865287024801136 0.387354946786856 -74.2516529332799 43.2730039093272 -1.7158885731359 0.0868895708425806 CRYBB2P1 other 1 1 1 0.865287024801136 -1.7158885731359 0.978645609614988 -8.97619253755768 61.7584414576469 -0.145343572889763 0.884506780507446 2.53969175769591 96.0561307102866 0.0264396633397179 0.978918755387646 MFNG other 1 1 1 -0.145343572889763 0.0264396633397179 0.374797747501972 5.28287460942807 13.5991568664989 0.388470745744707 0.697857754034118 -17.0993234614862 21.0215836558491 -0.813417473270546 0.416423739592256 CARD10 other 1 1 1 0.388470745744707 -0.813417473270546 0.0033376591895109 4.56415545730486 4.7908927149826 0.95267327590771 0.341281067293674 -16.0463887466461 7.67677522845385 -2.09025121475101 0.0371712907090937 LRP5L other 1 1 1 0.95267327590771 -2.09025121475101 2.40240545137222e-06 377.582136167889 207.248871846812 1.82187788431958 0.069155370125572 -983.933985447195 343.929081059608 -2.86086300819867 0.00442708627548261 SLC25A1 other 0.0141429608922283 1 1 1.82187788431958 -2.86086300819867 0.000283261240729013 50.4881163297597 94.3664105924174 0.535022112347002 0.592906697874068 -448.921458948062 151.222750641367 -2.96861058963742 0.00315601345491584 GRK3 other 1 1 1 0.535022112347002 -2.96861058963742 1.89240524537975e-18 363.587055966874 102.221865502783 3.5568423074511 0.000416473258241323 -736.623028476653 157.998135799559 -4.66222607468708 4.16433406846176e-06 GGA1 other 1.59359445713429e-14 0.0358757379997981 1 3.5568423074511 -4.66222607468708 1.39822395830506e-22 227.935407962353 74.8110048216199 3.04681655467461 0.00245292353718184 -807.099942371415 124.159005050716 -6.50053487495113 2.18820860672271e-10 HIRA other 1.22134862757947e-18 2.06413717872153e-06 1 3.04681655467461 -6.50053487495113 1.73915865575689e-05 352.165065961345 186.158108358938 1.89175249504751 0.0591863854568911 -640.766923935783 287.733294046407 -2.22694744471398 0.0264607606755308 SH3BP1 other 0.0943667486613691 1 1 1.89175249504751 -2.22694744471398 0.000114043254719593 935.758780358796 1671.43658216129 0.559852997323291 0.575867219975525 -8545.30313916658 2701.1862852209 -3.16353714141109 0.00166766134833227 SEZ6L other 0.561548986239277 1 1 0.559852997323291 -3.16353714141109 0.24853538858875 -0.943740447259801 406.306276543359 -0.00232273164788064 0.998147792298826 820.848771287029 628.002961418887 1.30707786700947 0.191875188619473 LGALS1 other 1 1 1 -0.00232273164788064 1.30707786700947 6.93459771041756e-18 266.454060895012 71.5253523570701 3.72530930801732 0.000220708421146214 -556.672593897105 115.591164447702 -4.81587495512227 2.02513765652862e-06 HPS4 other 5.79316292728283e-14 0.0176754014661818 1 3.72530930801732 -4.81587495512227 4.00803785183319e-10 137.093032786879 128.001282580881 1.07102858676633 0.284747733910221 -953.635706967222 202.127204944495 -4.71799779366214 3.21058281293102e-06 PIK3IP1 other 2.8978113668754e-06 0.0277715413318533 1 1.07102858676633 -4.71799779366214 1.19582727773337e-06 130.643208474705 36.327316361669 3.59628019791062 0.000359731007567639 -45.8358432428914 56.1489289548161 -0.816326225559462 0.414759353978836 NOL12 essential 0.00719529273012169 1 1 3.59628019791062 -0.816326225559462 4.47982499950619e-25 175.076028364995 33.0616481252829 5.29544164590849 1.88670324877973e-07 -272.675952028605 53.4304869451491 -5.10337763360701 4.99077945077857e-07 SRRD other 3.96778100206263e-21 0.00444728356858878 0.00171859798931346 5.29544164590849 -5.10337763360701 5.24110515520458e-16 178.765324465219 118.014457472679 1.51477478517074 0.130554038548965 -1121.93578105338 186.373603138905 -6.01982127381631 3.70816969847457e-09 PATZ1 other 4.28041058025558e-12 3.44748536867181e-05 1 1.51477478517074 -6.01982127381631 0.0264240703478437 83.0812674117355 64.58007582933 1.28648451313838 0.198956701820049 -106.25082112931 99.8175051946252 -1.06445077866995 0.287713686659221 TRIOBP other 1 1 1 1.28648451313838 -1.06445077866995 1.46788288485298e-21 195.623956233804 47.0990347025191 4.15345999062144 3.94149707483785e-05 -407.464583933198 76.116119476743 -5.35319701968908 1.40013160051951e-07 TFIP11 essential 1.27206730801359e-17 0.00126599899318974 0.333687142355773 4.15345999062144 -5.35319701968908 5.44522977631455e-07 112.765307142972 46.2215373231139 2.43967019864962 0.0150973742269941 -164.843291670947 71.4344121552408 -2.30761738911928 0.0214868286081818 GCAT other 0.0033635184328295 1 1 2.43967019864962 -2.30761738911928 0.0373843107469352 -0.766377989866828 1.82481591940368 -0.41997550641561 0.674709283462518 -6.88477475354457 2.96856156095449 -2.31922923347794 0.020841808657766 GGTLC2 other 1 1 1 -0.41997550641561 -2.31922923347794 0.641492412925412 9.12338371088597 18.9136248581773 0.482370977498874 0.629784507999618 -11.7105946872551 30.5660559401299 -0.383124165911127 0.701814426503492 CRYBB1 other 1 1 1 0.482370977498874 -0.383124165911127 5.8502337544363e-16 2430.76776688161 634.762116658046 3.82941530865033 0.000147230802267388 -3683.32305423862 981.011478370039 -3.75461769352434 0.000197079528080436 EIF3L essential 4.77496079037091e-12 1 1 3.82941530865033 -3.75461769352434 9.00803967215591e-19 384.467767929085 158.971914178463 2.41846347460771 0.0159940109102437 -1346.33126510879 241.40710897027 -5.57701581718785 4.29393448842862e-08 SNU13 other 7.6090911110701e-15 0.000392680308966797 1 2.41846347460771 -5.57701581718785 9.6485317219384e-07 129.312004335628 61.3434731896013 2.10799939442536 0.0355998744356355 -240.512937955118 94.8050454537486 -2.53692128730063 0.0115300366310328 MICALL1 other 0.00585472904887222 1 1 2.10799939442536 -2.53692128730063 3.31934002450795e-08 304.001278523515 341.806080318616 0.889396930095974 0.374279121185175 -2156.24167878515 528.254096092935 -4.08182670940579 5.31334476848721e-05 POLR2F essential 0.000220105437025122 0.431762395887271 1 0.889396930095974 -4.08182670940579 0.0211481801330425 1002.52905735246 516.389311388151 1.94142100783897 0.0528496853103955 2215.37093670092 798.068801658306 2.77591472326397 0.00574106912229338 SOX10 other 1 1 1 1.94142100783897 2.77591472326397 0.00514492888068831 9.02391828995022 3.53630000921976 2.55179658581661 0.0110563003104544 0.44633314453196 5.34116168475644 0.0835648068482528 0.93344071418196 CCDC134 other 1 1 1 2.55179658581661 0.0835648068482528 5.00273807173096e-18 91.7960311753681 21.283986737849 4.31291525906321 1.99446225094437e-05 -138.021124906909 33.6126046117013 -4.10623117432742 4.80287105552046e-05 DEPDC5 other 4.1857909446173e-14 0.391433991024917 0.171104916508518 4.31291525906321 -4.10623117432742 0.0153019705017112 -63.4056582098514 48.7263200308783 -1.30126096470389 0.193854777812983 92.1951505306002 75.3055010602887 1.22428174877676 0.221505560273041 PICK1 other 1 1 1 -1.30126096470389 1.22428174877676 1.09629377397542e-07 190.14899771007 71.7764927810721 2.64918206981846 0.00836107465804935 -299.813858127958 115.022269063778 -2.60657228003142 0.00945792875665632 TTC28 other 0.000703820602892218 1 1 2.64918206981846 -2.60657228003142 0.00267168551499721 -0.891068715908262 6.35007677770565 -0.140324085377471 0.888468589493408 25.7533720043897 9.8139098789605 2.624170419539 0.00899019474088022 SLC16A8 other 1 1 1 -0.140324085377471 2.624170419539 0.00934781103279562 57.8723582141013 18.9279473493566 3.05750841049695 0.00236886865659263 63.1173110547446 28.5884192206239 2.20779297265975 0.0277774373573508 CENPM other 1 1 1 3.05750841049695 2.20779297265975 8.94315607030087e-16 -203.182339251846 665.783043385222 -0.305178002459706 0.760375885918924 -6860.51893146501 1005.58631123446 -6.82240684346928 2.99625290073404e-11 SEPT3 other 7.27883472561788e-12 2.84823800743778e-07 1 -0.305178002459706 -6.82240684346928 0.037728995244478 -272.287189685831 666.895582439547 -0.408290588295378 0.683259871574101 -2510.87145698197 1097.11375853989 -2.2886154124287 0.0225770665719884 TPTEP1 other 1 1 1 -0.408290588295378 -2.2886154124287 0.0324453613779557 -5.75067430240338 8.12259486909224 -0.707984873686807 0.479332083931513 19.8861096429332 12.7135508703846 1.56416644300819 0.118502320146716 KDELR3 other 1 1 1 -0.707984873686807 1.56416644300819 9.25056753695932e-07 17.9976555766258 11.7485621617225 1.5319028259699 0.126269993161108 -52.173684340137 17.744809519998 -2.94022228197707 0.00345382407189643 CYP2D6 other 0.00562064483545648 1 1 1.5319028259699 -2.94022228197707 6.29257315984784e-10 2374.32254812756 902.438860708465 2.63100654404841 0.00881416342133494 -4554.61725505787 1412.50456879074 -3.2244973614189 0.00135659112638314 DDX17 other 4.51869678608673e-06 1 1 2.63100654404841 -3.2244973614189 3.2898438757922e-10 140.006942212256 61.7074970525875 2.26888058825237 0.0237624441697726 -306.201652123691 91.5145470347009 -3.34593419347401 0.000890869742335522 TCF20 other 2.38447884117419e-06 1 1 2.26888058825237 -3.34593419347401 1.96967736414855e-09 71.0916296077967 13.9502747073251 5.09607381211409 5.17127267868907e-07 -5.97108922307562 22.3554006155438 -0.267098287602321 0.789519487192693 HSCB essential 1.38645589662416e-05 1 0.00466965922885623 5.09607381211409 -0.267098287602321 0.000101247826984429 98.1493808909838 39.5392042266416 2.48233070975289 0.0134280513047176 -78.0842299484259 61.5038714412607 -1.26958235503923 0.204910657039234 CBY1 other 0.50178423053483 1 1 2.48233070975289 -1.26958235503923 4.67695474973026e-14 280.32090298773 70.8666100465073 3.95561326841745 8.90807015307316e-05 -346.977058509693 110.234157693076 -3.14763650188882 0.00175891931178523 TOMM22 essential 3.70274507536145e-10 1 0.742309485855586 3.95561326841745 -3.14763650188882 0.00179845831550874 51.0883134793733 15.2193426094838 3.35680159059816 0.000857272094821298 22.5650650250506 24.5916877035322 0.917589117798105 0.359338994986275 RSPH14 other 1 1 1 3.35680159059816 0.917589117798105 0.441383047723258 101.010648014693 84.4273792291672 1.19642050880808 0.232181205017405 144.621776040268 135.295392039659 1.06893349329943 0.2856897295573 XBP1 other 1 1 1 1.19642050880808 1.06893349329943 8.84908700425094e-23 328.061896140156 68.1211244296032 4.81586143633283 2.02381942885573e-06 -538.052580949205 109.164518904094 -4.92882290281432 1.17656719983271e-06 RTCB essential 7.73587185911617e-19 0.0103514382241282 0.017997826180814 4.81586143633283 -4.92882290281432 1.8606343304647e-15 249.284017650721 56.3860784613265 4.42102065710594 1.24164705813594e-05 -268.069824826606 87.7094566922402 -3.05633890501938 0.0023782523301332 JOSD1 other 1.5078580614086e-11 1 0.107476969352247 4.42102065710594 -3.05633890501938 3.09941178261258e-07 257.167792622755 128.541464761651 2.00066020018995 0.0460485683152954 -627.762346145044 206.006268708299 -3.04729729867563 0.00244941229976759 FBXO7 other 0.00194147154062852 1 1 2.00066020018995 -3.04729729867563 9.64055655923161e-15 475.750570773144 117.65768971726 4.04351446910447 6.22391231217288e-05 -603.478343313919 184.158763008635 -3.27694611678959 0.00113304697894755 GTPBP1 other 7.71533741435306e-11 1 0.522497438606913 4.04351446910447 -3.27694611678959 3.86390182255131e-20 797.591863774279 189.185509029456 4.21592471783922 3.02472986177937e-05 -1141.22777198497 280.569249950383 -4.0675440098542 5.63690237761716e-05 POLDIP3 other 3.3059543993749e-16 0.456476354539438 0.257495253133278 4.21592471783922 -4.0675440098542 5.09727914074747e-05 -56.8555724336428 43.8971318867622 -1.29520016433667 0.195933439080751 196.45314998401 70.9297757557111 2.76968519766104 0.00584950178163329 RAB36 other 0.26179625666879 1 1 -1.29520016433667 2.76968519766104 0.014038640865507 -1113.82114589372 1906.70688587266 -0.584159607408114 0.559415044470877 -8174.50980726427 3055.77326201616 -2.67510351925484 0.00775169227671034 TIMP3 other 1 1 1 -0.584159607408114 -2.67510351925484 1.30665120358745e-23 462.392926713244 101.553638373108 4.55318917294145 6.86058317179793e-06 -655.730954705921 149.136623748304 -4.39684725471986 1.3809222943519e-05 PPP6R2 other 1.14763175211086e-19 0.11603890039439 0.0599614969215139 4.55318917294145 -4.39684725471986 2.03072726106723e-15 619.67006698976 263.75650831766 2.34940199558393 0.0192488795688763 -1778.73153263067 387.385759628154 -4.59162859868171 5.76203416018304e-06 SBF1 other 1.64407679056003e-11 0.0493402985136474 1 2.34940199558393 -4.59162859868171 0.204423483500661 664.256262157861 372.21242798784 1.78461602088032 0.0750172204976879 657.815765598853 582.589888339663 1.12912321131007 0.25946529635096 SUN2 other 1 1 1 1.78461602088032 1.12912321131007 0.000105642116626195 144.191414549245 321.232599580143 0.448869183070792 0.653748531597536 -1409.92708913157 476.40006883286 -2.95954425990275 0.00324846925765444 CYB5R3 other 0.522505908833162 1 1 0.448869183070792 -2.95954425990275 4.99932886729256e-11 82.3573666515919 23.9032217954266 3.44545046506447 0.000625206879244426 -103.531825711218 37.4135151586361 -2.76723064572349 0.00589350587028424 DNAL4 other 3.71000195241781e-07 1 1 3.44545046506447 -2.76723064572349 1.3598277105239e-05 186.241592390508 85.2562325462349 2.18449240399531 0.029457996976037 -218.121820434322 125.217954311789 -1.74193726157836 0.0822246195334643 LMF2 other 0.0745865499222357 1 1 2.18449240399531 -1.74193726157836 2.19016533173566e-10 248.424633058932 45.6217296467695 5.44531377881512 8.64383808237558e-08 -17.8617446190297 73.7225245138287 -0.242283409810244 0.808674230858933 RHBDD3 other 1.59356429537087e-06 1 0.000792034883488075 5.44531377881512 -0.242283409810244 9.81907779789214e-06 378.88238814062 113.353838951664 3.34247513489316 0.00090176427709607 -76.4196059828805 167.268737075204 -0.456867238427956 0.647993482784348 PACSIN2 other 0.0546431679452697 1 1 3.34247513489316 -0.456867238427956 1.51952891468801e-22 98.5001751698646 22.5265544397518 4.37262500278538 1.53620075542423e-05 -146.373423790881 33.2409413447379 -4.4034079021066 1.34152248908346e-05 TTLL1 other 1.32700460119704e-18 0.112822041331919 0.132420505117569 4.37262500278538 -4.4034079021066 5.12946487427901e-05 -125.21181558602 131.559756280134 -0.951748613150379 0.341750586316656 -879.591831282243 212.594249110901 -4.1374206261967 4.2143229062401e-05 RASL10A other 0.263346726645484 0.34473161373044 1 -0.951748613150379 -4.1374206261967 0.000260353420528568 207.839280645208 243.504090762595 0.853535067909151 0.393830252853765 -1095.40759764223 393.490918460479 -2.78381926050029 0.00560542746572234 AP1B1 other 1 1 1 0.853535067909151 -2.78381926050029 0.000112495029621379 269.144640706663 79.9921017836028 3.36464019203748 0.000834364004337057 -13.0014687293626 125.326072504606 -0.103741132786913 0.917422594488935 HMGXB4 other 0.554375505974154 1 1 3.36464019203748 -0.103741132786913 1.74613579944486e-16 312.814399639557 72.0439053445754 4.34199670525094 1.76000346620125e-05 -399.512197942479 112.895114494216 -3.53879084787986 0.000445461467355111 TOM1 other 1.43549824072362e-12 1 0.151360298093307 4.34199670525094 -3.53879084787986 0.712089753739164 -114.480401398219 180.290844612053 -0.634976233233344 0.525775468892057 -233.21841901994 293.29230713981 -0.79517400675895 0.42694297321143 NEFH other 1 1 1 -0.634976233233344 -0.79517400675895 0.000976030151025334 97.9018199071414 47.5681254888558 2.05813911944203 0.0401706020429465 -68.501014825107 69.8644918532004 -0.980483977025722 0.327391011972218 CHKB other 1 1 1 2.05813911944203 -0.980483977025722 0.432196154984405 -218.451897627272 267.084785078616 -0.817912175577397 0.413857187509433 122.370745802467 415.653363297949 0.294405763570712 0.768588948825586 HMOX1 other 1 1 1 -0.817912175577397 0.294405763570712 2.38872587466394e-08 49.3303425223475 16.9081367617494 2.91755047983439 0.00370986034534086 -50.2217081048591 24.8304489225435 -2.02258558681406 0.043724448294911 MCAT other 0.000159805761015017 1 1 2.91755047983439 -2.02258558681406 3.18375019124061e-13 162.526246023331 26.7825131313981 6.06837174786242 2.7993720214894e-09 -25.2075821845176 43.5690735389948 -0.57856594453303 0.563179462370723 THOC5 essential 2.48014139897643e-09 1 2.62693070496565e-05 6.06837174786242 -0.57856594453303 0.000888500631417074 368.971398865841 97.6569827809596 3.77823877370272 0.000180045312644887 361.953931687173 151.979654440023 2.38159464844694 0.0176690477017009 MCM5 essential 1 1 1 3.77823877370272 2.38159464844694 0.139604385650975 118.608454491025 59.6631331156846 1.98796892313797 0.0474400927751146 111.675263496797 87.6287311021687 1.27441379205402 0.20319561847668 ARSA other 1 1 1 1.98796892313797 1.27441379205402 0.256444246862603 109.772896166656 118.079689114081 0.929650958520054 0.353065070131822 284.161916923309 173.405960139256 1.63870905414732 0.101993583643179 TSPO other 1 1 1 0.929650958520054 1.63870905414732 0.155976695757031 -66.8889870964085 64.751749809051 -1.03300663369963 0.302176077268502 -193.779577114538 100.760549453979 -1.92316911891241 0.055112759361802 RASD2 other 1 1 1 -1.03300663369963 -1.92316911891241 4.87371618283778e-15 222.997451112953 109.644390778059 2.03382452609311 0.0425728335370059 -768.214482085173 161.018300432548 -4.77097621836459 2.50330576607279e-06 TTLL12 other 3.91992992585643e-11 0.0217562304129386 1 2.03382452609311 -4.77097621836459 0.000434773810678962 -39.7158533014129 195.224954135006 -0.203436356163504 0.838888463941703 -982.835420578462 303.580524529341 -3.2374784980104 0.00129753373037074 CBX7 other 1 1 1 -0.203436356163504 -3.2374784980104 0.397147288033279 37.4708883302876 61.791413993655 0.606409303631331 0.544557151575283 127.947360609967 96.0874594885603 1.33157189596838 0.183693465478436 PDGFB other 1 1 1 0.606409303631331 1.33157189596838 0.0104787317429535 154.367287223598 59.3607985343549 2.60049209301419 0.00962379858617807 20.6029483000149 96.566553855051 0.213354908894652 0.831149420507183 CABP7 other 1 1 1 2.60049209301419 0.213354908894652 1.6566381968863e-10 4154.69914518134 1980.98691814019 2.09728752226284 0.0365408206492218 -11857.3961609354 3080.49270831882 -3.84918819282212 0.000136156682628916 RPL3 essential 1.21067119428451e-06 1 1 2.09728752226284 -3.84918819282212 4.19003798970533e-09 147.710822434312 30.470640067478 4.84764422759755 1.73794382622686e-06 -28.3559659871959 49.5688194519663 -0.572052477761221 0.567579895603629 ZMAT5 essential 2.9078863648555e-05 1 0.0154885553793338 4.84764422759755 -0.572052477761221 3.13080362852399e-07 229.810694798746 206.362232269211 1.11362768405677 0.266055322072109 -1166.23738556029 321.121390098539 -3.63176487621214 0.000315115457987532 RBFOX2 other 0.00195988307145602 1 1 1.11362768405677 -3.63176487621214 0.00170387202025108 495.884630316607 465.26520207954 1.0658106991458 0.287096375997726 -1457.32309550516 718.983301690605 -2.02692203292961 0.0432756308244257 SYNGR1 other 1 1 1 1.0658106991458 -2.02692203292961 2.60584599541597e-24 214.753418600635 66.2414774197993 3.2419780923613 0.00127769731187967 -644.665365369687 102.364234271724 -6.29775985681127 7.35326982490608e-10 TAB1 other 2.29731382955872e-20 6.89957307670938e-06 1 3.2419780923613 -6.29775985681127 1.92129261250026e-06 174.79541501073 60.0348419990216 2.91156617041782 0.00377984558829758 -175.888460708254 96.8442762203552 -1.8161988252981 0.0700233655677263 ASCC2 other 0.0113894226069016 1 1 2.91156617041782 -1.8161988252981 1.72168622245905e-12 160.629918610411 127.073831578553 1.26406764174035 0.206878039020327 -1097.04657998654 204.987184708054 -5.35178129085957 1.40747492060241e-07 MTMR3 other 1.31915598364812e-08 0.00127249807571664 1 1.26406764174035 -5.35178129085957 4.53560674031651e-18 240.106995729443 81.6312048686203 2.94136287852028 0.0034409782092612 -646.927594685535 126.146277295393 -5.12839228042095 4.39631909863986e-07 MIEF1 other 3.79630284164492e-14 0.00392503369126567 1 2.94136287852028 -5.12839228042095 0.492401543127045 98.9675616485126 116.079026112041 0.852587801287956 0.394354955091053 214.350331351861 181.750609192127 1.1793651328303 0.238894481565678 APOL4 other 1 1 1 0.852587801287956 1.1793651328303 0.852265226765446 -70.3813035069238 129.759534851769 -0.542397933125486 0.587820888805896 -41.4222887454128 203.17085090835 -0.203879092695725 0.838542891784011 APOL1 other 1 1 1 -0.542397933125486 -0.203879092695725 8.28630079649583e-07 5.6557201116121 11.5119569338571 0.491290937249635 0.623467899435217 -62.2001860198897 16.9078981598356 -3.67876512100392 0.000263672253940457 PNPLA3 other 0.00504884307530491 1 1 0.491290937249635 -3.67876512100392 0.127175897580093 -499.605911715343 626.115360240852 -0.797945464112486 0.425335524840613 977.973473363873 980.339445977814 0.997586578175908 0.319031927298735 MYH9 other 1 1 1 -0.797945464112486 0.997586578175908 0.0408884869044968 -42.8574743619554 55.30052278833 -0.774992209856642 0.438763400586049 -202.918308294456 85.4657929191465 -2.37426344931268 0.0180150994278107 CACNA1I other 1 1 1 -0.774992209856642 -2.37426344931268 4.10570362872359e-15 211.386381732146 62.4625183373784 3.38421164177829 0.000778215893921606 -325.62550890107 91.7293485973221 -3.54985088066543 0.000427269890754146 SAMM50 essential 3.31042883583983e-11 1 1 3.38421164177829 -3.54985088066543 3.85494912502451e-14 528.02619528428 154.896632380929 3.40889396475538 0.000712768498374341 -917.818373673886 242.529234091518 -3.78436181976953 0.000175601814073785 TXN2 other 3.05890213070695e-10 1 1 3.40889396475538 -3.78436181976953 2.4503529586325e-13 -6.5147401803151 124.737882282882 -0.0522274393398863 0.958371334432035 -1226.07386302227 195.308203846981 -6.27763626346626 8.29699033311465e-10 FOXRED2 other 1.91397069598785e-09 7.77925813632829e-06 1 -0.0522274393398863 -6.27763626346626 1.05482963216242e-17 1019.28722375494 186.832323851439 5.45562567944843 8.18708398471511e-08 -759.296467476333 292.532508362053 -2.59559688503607 0.00976055336874422 EIF3D essential 8.7993887914989e-14 1 0.000750673730558529 5.45562567944843 -2.59559688503607 3.21814356853128e-14 166.459419557966 82.0028362704805 2.02992270912328 0.0429696878936837 -605.995802822857 125.227070109161 -4.83917576522878 1.81102759108223e-06 TNRC6B other 2.55713687955495e-10 0.0158247590908765 1 2.02992270912328 -4.83917576522878 3.30783592245357e-12 388.456596962784 89.5802996567312 4.33640653638509 1.79990462295809e-05 -271.612510885861 136.798664237805 -1.98549095781888 0.0477144529708578 SGSM3 other 2.52156332368635e-08 1 0.154701802343248 4.33640653638509 -1.98549095781888 5.82020600619543e-12 145.593451433122 44.7293474755133 3.25498715385521 0.0012219160183767 -225.340100849258 69.563205625056 -3.23935762914429 0.00128921516682086 IFT27 other 4.40822402909242e-08 1 1 3.25498715385521 -3.23935762914429 0.427546876877867 -21.6954120222932 20.7137682584409 -1.04739088279856 0.295496961464388 -40.5335058386416 32.2141100184952 -1.25825316345446 0.208970529680522 PVALB other 1 1 1 -1.04739088279856 -1.25825316345446 0.0197359186382337 -369.665857452444 267.09986382134 -1.38399867436739 0.167068523220378 -1079.54475093065 392.343110075424 -2.75153232771979 0.00617953075955065 KIAA0930 other 1 1 1 -1.38399867436739 -2.75153232771979 0.822745878999903 11.7240246815287 27.287792842367 0.429643568069235 0.667666217619741 26.3973372257609 42.4380513394852 0.622020483801062 0.534252044120833 NCF4 other 1 1 1 0.429643568069235 0.622020483801062 0.123067962942186 -11.7931429140128 18.3791095953454 -0.641660187770982 0.521429488799362 32.5845939490447 28.583242370937 1.13998942199001 0.254913711391363 CSF2RB other 1 1 1 -0.641660187770982 1.13998942199001 8.58108892342359e-08 122.952902210154 30.4766654657698 4.03432922634695 6.46327800312556e-05 -31.7709858857346 46.5411160948987 -0.682643403328633 0.495193902731677 SLC25A17 other 0.00055588294045938 1 0.542269024462234 4.03432922634695 -0.682643403328633 0.016145415927063 74.2207745300139 44.4250808589123 1.67069531658768 0.095501143417776 -42.4572651831488 65.2560212505256 -0.650626016872072 0.515631427602629 FAM118A other 1 1 1 1.67069531658768 -0.650626016872072 0.00141130536104916 122.993381767516 67.3288923314948 1.82675486716692 0.068417061048744 -142.851402158529 104.710080654028 -1.36425644280156 0.173187432581192 KCTD17 other 1 1 1 1.82675486716692 -1.36425644280156 2.63918307767448e-21 1259.4650222355 318.544623605627 3.95381032641372 8.97004857278182e-05 -2356.77623944266 486.451587864381 -4.84483204133298 1.76275077749328e-06 ST13 other 2.28421295372727e-17 0.0154170182999563 0.747115345626998 3.95381032641372 -4.84483204133298 0.500899649967336 -1.87375597133755 12.3740576752408 -0.15142615466281 0.879709277282887 15.8962535385706 19.2441689195289 0.826029619935373 0.409236999292213 IL2RB other 1 1 1 -0.15142615466281 0.826029619935373 1.83115354224745e-11 285.814665592266 64.9843192623956 4.39820973484688 1.37264991349275e-05 -158.979774375503 98.6820642036482 -1.61103008594773 0.107895169802492 RBX1 essential 1.37226646456024e-07 1 0.118610679024909 4.39820973484688 -1.61103008594773 1.41372301871229e-19 200.298751007253 40.9091085881399 4.89618957537791 1.37762022604098e-06 -211.437711522965 62.1226062845737 -3.40355506905815 0.000726474206852105 L3MBTL2 other 1.20237142741481e-15 1 0.0123021486185459 4.89618957537791 -3.40355506905815 0.0621831685464761 146.087832393235 165.917542948686 0.880484545497494 0.379080834779529 -283.694802578563 251.954407026441 -1.12597674288266 0.260793335144279 CHADL other 1 1 1 0.880484545497494 -1.12597674288266 4.74718955113723e-09 693.531224818692 187.546626598264 3.69791361965831 0.000245056224541771 -452.907211925872 284.799294002257 -1.59026802897301 0.112497537073641 RANGAP1 essential 3.28790348311765e-05 1 1 3.69791361965831 -1.59026802897301 2.25855112891031e-22 330.562852538267 225.036361554799 1.46893084412836 0.142571020268427 -2434.59903303788 341.729403818755 -7.12434752711281 4.34037927349065e-12 ZC3H7B other 1.96990829463557e-18 4.1550450785126e-08 1 1.46893084412836 -7.12434752711281 4.37343178358332e-13 98.7689363416603 19.336685990483 5.10785231710706 4.87624159746804e-07 -37.2766317485897 29.3637620591778 -1.26947738077515 0.204946488458209 PHF5A essential 3.39553243677409e-09 1 0.00440568428331237 5.10785231710706 -1.26947738077515 3.33137707027185e-12 194.653706688136 387.614818066534 0.502183347012094 0.615791494034428 -3198.17840451251 588.613234652465 -5.43341232617852 9.201808612115e-08 ACO2 essential 2.5391756029612e-08 0.000835800276238406 1 0.502183347012094 -5.43341232617852 3.490503246242e-17 896.664786462517 279.335563999819 3.20999150134388 0.00142526216209173 -1908.25515713136 424.185563130822 -4.49863296394847 8.77764825647382e-06 POLR3H essential 2.89467434210849e-13 0.0745310113457192 1 3.20999150134388 -4.49863296394847 2.02052578004945e-08 204.438562408939 54.0937049754667 3.7793410989626 0.000179065066735777 -79.924940272071 79.0724412960159 -1.01078124011454 0.312680467089533 TRMU other 0.000135880358708326 1 1 3.7793410989626 -1.01078124011454 5.70711482592875e-13 300.893231265108 69.058546221547 4.35707450747386 1.64454747884396e-05 -226.028565672846 104.868989463876 -2.15534226875244 0.031680514682726 PMM1 other 4.41787758675145e-09 1 0.141595537928465 4.35707450747386 -2.15534226875244 3.25183032627806e-32 168.202457695402 86.1237400176744 1.95303243520176 0.0514536255658575 -1141.66611603546 130.78337264049 -8.72944391160322 5.45859267939625e-17 DESI1 other 2.9669699896961e-28 5.32922403289456e-13 1 1.95303243520176 -8.72944391160322 1.67802392446735e-05 750.581835842636 182.280138763306 4.11773790021787 4.57602615956001e-05 264.717602199752 266.451254879437 0.99349354657583 0.32101927487067 CERK other 0.0912509410125347 1 0.386399648913248 4.11773790021787 0.99349354657583 1.13853607716399e-16 156.771200355614 46.2867923829527 3.38695321677448 0.000770529429790931 -267.74792944182 67.9664372321845 -3.93941392760003 9.50267906311163e-05 BRD1 other 9.38722995621714e-13 0.757933682073784 1 3.38695321677448 -3.93941392760003 1.22459018721977e-07 138.515501248017 42.1048192635329 3.28977783709395 0.00108363388120843 -82.7909251302644 61.8257262670322 -1.3391015379695 0.181232131066329 ZBED4 other 0.000784227555895544 1 1 3.28977783709395 -1.3391015379695 0.00355828478342718 -3159.54120346811 1692.38395289629 -1.86691749118808 0.0625809711742926 -8270.12178044391 2473.57366936888 -3.34339012532988 0.0008987037121646 MLC1 other 1 1 1 -1.86691749118808 -3.34339012532988 6.45530479385064e-06 76.5915492957768 54.4005823637373 1.40791781940246 0.159866364157954 -206.187046521551 79.5210248101255 -2.59286203886166 0.00983729638885141 HDAC10 other 0.03656284635237 1 1 1.40791781940246 -2.59286203886166 0.00883810449776309 -22.3364757500241 83.0393049062903 -0.268986786139778 0.788066798848687 -185.393441316846 96.2935818947554 -1.92529385311964 0.0548412569508489 KCNK10 other 1 1 1 -0.268986786139778 -1.92529385311964 6.42257245041986e-07 388.738439468195 180.697280080894 2.15132424402939 0.0319968324291091 -650.506204903126 269.450317980396 -2.41419720629335 0.0161790252401823 ABHD4 other 0.00394731302802805 1 1 2.15132424402939 -2.41419720629335 4.83395246133987e-05 253.867774666906 92.4128031399507 2.74710609397322 0.00626092792320355 -123.967790883156 137.075050350058 -0.90437895566385 0.366292784518278 KHNYN other 0.248811628762484 1 1 2.74710609397322 -0.90437895566385 1.32046550562428e-18 289.9452152259 86.4560459602449 3.353671938215 0.000867599176449952 -433.513244100556 114.902636594029 -3.77287464370582 0.000183835192378806 FKBP3 other 1.11368060744352e-14 1 1 3.353671938215 -3.77287464370582 4.10440046988257e-14 327.068008975201 90.2248520969668 3.62503236495964 0.000322945583786679 -419.299191504006 133.829682942187 -3.13308066107532 0.00184620430239967 SDR39U1 other 3.25561045271086e-10 1 1 3.62503236495964 -3.13308066107532 2.7456610337222e-18 395.780322786509 106.235196745985 3.72551032905642 0.00022041622902522 -665.491221053116 158.414711782606 -4.2009432934889 3.22227346657847e-05 RBM23 other 2.30608070222328e-14 0.26570867005406 1 3.72551032905642 -4.2009432934889 2.00854009821881e-26 715.181160772852 112.111138457241 6.37921593353207 4.53133697640037e-10 -555.911760784584 167.17673831573 -3.32529373634917 0.000957563992340056 PRMT5 essential 1.79061349756207e-22 1 4.28573851227947e-06 6.37921593353207 -3.32529373634917 0.390669791866426 -5.53132938187955 22.0664972219899 -0.250666398306634 0.802189852513184 23.7732404485159 30.0520986761294 0.791067562525982 0.42933368846418 COCH other 1 1 1 -0.250666398306634 0.791067562525982 1.28658860279442e-20 5.4710414902599 27.1901369622769 0.201214193876637 0.840624714520544 -262.361278320892 37.0299223654552 -7.08511553795874 5.59897345405187e-12 AP4S1 other 1.1058229041018e-16 5.35261862207359e-08 1 0.201214193876637 -7.08511553795874 0.0372213393363397 21.2480068870007 8.84238460195366 2.40297248349796 0.0166802775930935 13.0492687240334 11.6438230008329 1.12070311641632 0.263032583184464 POLE2 other 1 1 1 2.40297248349796 1.12070311641632 2.47196625122476e-08 28.0337987049443 10.7869034550545 2.59887360832995 0.0096707742273657 -26.0018597709325 14.2044030215533 -1.83054928330871 0.0678518317432522 VCPKMT other 0.000165201504569351 1 1 2.59887360832995 -1.83054928330871 9.48097020276528e-16 83.9664633005194 118.186585592485 0.710456799133204 0.477801623160058 -837.528677901716 155.630380905127 -5.38152430798377 1.20972802072861e-07 SOS2 other 7.71371735696983e-12 0.00109601358678012 1 0.710456799133204 -5.38152430798377 0.000210848803302055 -5.54307281275839 28.1310019506297 -0.197044983413195 0.843884157228002 -110.413979209688 37.0400175808169 -2.98093754866011 0.00303453957166958 CDKL1 other 0.999306583968991 1 1 -0.197044983413195 -2.98093754866011 1.85499611220829e-07 192.209822696194 210.426907212194 0.913427970037932 0.361521170127647 -874.804544544725 277.043035517087 -3.15764856861298 0.00170067771730386 NIN other 0.00117699503319616 1 1 0.913427970037932 -3.15764856861298 0.0679232064225528 14.1704658123466 148.951368919038 0.0951348478042444 0.924251326481146 325.244703927312 196.105811449975 1.65851639746168 0.0979308184562118 PYGL other 1 1 1 0.0951348478042444 1.65851639746168 3.12678528280486e-07 424.509600659142 714.27791713333 0.594319928527066 0.552605703250107 -3151.58327320797 940.401229990483 -3.35131768515431 0.000874157355670732 TRIM9 other 0.00195768026556412 1 1 0.594319928527066 -3.35131768515431 1.00807098134317e-30 182.941018955679 43.2637480121226 4.22850602089348 2.86676911462978e-05 -244.504011596884 54.3572554565003 -4.49809339238163 8.79895787913919e-06 PSMC6 essential 9.14521994274521e-27 0.0746943534360126 0.244334731639896 4.22850602089348 -4.49809339238163 4.49823136975103e-10 16.9018920442553 42.5112147638626 0.397586663616657 0.691129025977555 -214.437057692499 53.4117608127232 -4.01479102035928 7.00183647230627e-05 GNPNAT1 other 3.24952234150814e-06 0.563787872750101 1 0.397586663616657 -4.01479102035928 5.13175387114876e-15 42.7964748083195 74.4928498149267 0.574504464719029 0.565922772383288 -454.408524853276 93.0035638294275 -4.88592593813588 1.44853100661238e-06 DDHD1 other 4.12644328779072e-11 0.0127079625210104 1 0.574504464719029 -4.88592593813588 0.0149851703284459 60.1145312537094 20.662746015774 2.90931956516418 0.00380787820915248 60.3777508724452 25.7221348503892 2.34730714319117 0.0193570883737744 CDKN3 other 1 1 1 2.90931956516418 2.34730714319117 8.3357233437916e-11 -63.058737506824 150.941976623787 -0.41776806503597 0.676322834610762 -887.235061605302 187.900963131299 -4.72182285188891 3.15786487899246e-06 CNIH1 other 6.15009668304944e-07 0.0273250047979218 1 -0.41776806503597 -4.72182285188891 7.63118159685052e-22 -15.4930275621392 25.8093389883506 -0.600287654369303 0.548627139108831 -225.740082615199 32.1288998737614 -7.02607569827046 8.2443939001241e-12 CGRRF1 other 6.62997057134373e-18 7.87339617461852e-08 1 -0.600287654369303 -7.02607569827046 4.64184046120193e-14 -34.0744319544586 139.535377447529 -0.244199231605418 0.807191131249 -708.302804833711 158.964614342686 -4.45572624928209 1.06362838308525e-05 ATP6V1D essential 3.67540927717969e-10 0.0899829612090119 1 -0.244199231605418 -4.45572624928209 1.56033916110573e-17 25.4328814457791 46.8055377728705 0.543373341188711 0.587150474732596 -233.311906468112 53.3787107347954 -4.37087938723904 1.54878733128621e-05 PIGH other 1.29882631770441e-13 0.129788378361784 1 0.543373341188711 -4.37087938723904 3.89481848099039e-13 158.452548942555 65.097383738618 2.43408474876319 0.0153300363757906 -185.221304301228 77.0439448562347 -2.40409943502833 0.0166286719842961 PSMA3 essential 3.02627395972954e-09 1 1 2.43408474876319 -2.40409943502833 4.33854323338732e-35 77.9073123325086 108.001647227288 0.721353000927415 0.471078988488935 -818.201032698862 123.168944542463 -6.64291665190639 9.18590335110424e-11 VTI1B other 3.9966660265964e-31 8.68802738947439e-07 1 0.721353000927415 -6.64291665190639 5.97881437465157e-18 83.1609298810656 32.8251243294642 2.53345361456619 0.0116430372189101 -118.103136189432 38.3667789225105 -3.07826561171489 0.00221319334001956 TIMM9 essential 4.99709305433378e-14 1 1 2.53345361456619 -3.07826561171489 1.76838940302245e-12 101.778022966534 52.7500517094434 1.92943930229957 0.0543219462088855 -143.077396095408 60.8882955945897 -2.34983414625456 0.019224794509888 GSTZ1 other 1.3544094437749e-08 1 1 1.92943930229957 -2.34983414625456 3.49287585879171e-11 30.6908973136392 46.7418602182774 0.656604105406103 0.511781115328999 -193.468719074435 54.6329878120772 -3.54124361164203 0.00044104836787008 KIAA0586 other 2.60114465204218e-07 1 1 0.656604105406103 -3.54124361164203 8.42083927609156e-13 -42.2626252688056 117.011483717364 -0.361183568707572 0.718136373574711 -603.189080354757 135.063939800251 -4.46595206127428 1.01563384673925e-05 TMED8 other 6.49583541757703e-09 0.0860174769983653 1 -0.361183568707572 -4.46595206127428 0.609278006055611 -10.7335586883493 10.7763092284055 -0.996032914502533 0.319784088338841 -10.4103932702713 12.4388712513887 -0.836924272297546 0.403091528224763 SAMD15 other 1 1 1 -0.996032914502533 -0.836924272297546 1.06002972682854e-25 -17.5961600629545 132.254105711886 -0.133048119513866 0.894216428300303 -964.431219868712 152.658183664715 -6.31758610456748 6.53884615206665e-10 AHSA1 other 9.4162440634179e-22 6.14063042140579e-06 1 -0.133048119513866 -6.31758610456748 3.45719538736631e-05 33.651263741911 115.60446616667 0.291089651271734 0.771120546321879 -314.651362204186 134.5046808405 -2.33933391936976 0.0197667271353328 DAAM1 other 0.181641045652226 1 1 0.291089651271734 -2.33933391936976 0.0156284011534446 -331.254318523615 225.190034518344 -1.47099901304306 0.142009424692105 -672.710862720846 259.93220750254 -2.58802427442267 0.00997363291362326 SPTLC2 other 1 1 1 -1.47099901304306 -2.58802427442267 0.739589431206282 -75.4079954476317 98.0609016616631 -0.768991455002218 0.442313789402303 -65.764880377397 115.893828598257 -0.567458001628105 0.570694445768838 RIN3 other 1 1 1 -0.768991455002218 -0.567458001628105 0.468951426569343 10.1142079477426 252.390495518888 0.0400736482843733 0.968052670029476 -198.606046780894 297.844973249724 -0.666810134862929 0.505244520299267 LGMN other 1 1 1 0.0400736482843733 -0.666810134862929 1.01756786811038e-35 16.0451670485057 14.1621951682698 1.13295762823934 0.257851838455248 -107.480325944875 16.3471294857425 -6.57487456979011 1.38852116996232e-10 ALKBH1 other 9.39418655839502e-32 1.31131939291241e-06 1 1.13295762823934 -6.57487456979011 1.61762460381116e-26 75.8238295360329 64.5849284971516 1.17401739539554 0.241026007096611 -395.23093032735 74.5490495241736 -5.30162266118753 1.8239375329234e-07 SNW1 essential 1.4425976216788e-22 0.00164373250467057 1 1.17401739539554 -5.30162266118753 0.0436042886184302 -291.077408818731 501.669733686239 -0.58021720122502 0.562066518822538 -1105.09896570495 592.018364648727 -1.86666331940676 0.0626165634213495 CHGA other 1 1 1 -0.58021720122502 -1.86666331940676 6.71779478363987e-13 -823.227980402835 632.121430299732 -1.30232569399282 0.19348945676456 -4031.57055240168 745.963868849852 -5.40451182792227 1.06946342232567e-07 ITPK1 other 5.19419892671035e-09 0.000969789431364917 1 -1.30232569399282 -5.40451182792227 1.05128698981279e-05 27.6543000893397 122.103199300298 0.226483009845854 0.820931429180432 -352.896036112288 140.80408859154 -2.50629111442927 0.0125619940824488 DHRS7 other 0.058293863585119 1 1 0.226483009845854 -2.50629111442927 5.02163185607708e-21 -102.151779286224 132.640470495132 -0.770140356897885 0.441631810102673 -945.609559806643 152.374116461101 -6.20584113475757 1.26233959246403e-09 PPM1A other 4.33567694453695e-17 1.18129739062784e-05 1 -0.770140356897885 -6.20584113475757 6.42422111143971e-07 -0.980948523962902 25.3835467348126 -0.0386450535936165 0.969191069837107 -87.4463094766225 29.1660008590463 -2.99822762466592 0.00287086867956128 SIX4 other 0.00394731302802805 1 1 -0.0386450535936165 -2.99822762466592 1.2322699592877e-05 -242.486704987658 190.568392762434 -1.27243926168778 0.203893704501055 -763.293940847438 217.103587746251 -3.51580528341877 0.000484241698269688 GALNT16 other 0.0678857520571593 1 1 -1.27243926168778 -3.51580528341877 0.549696938677221 -10.92524465192 13.9961403052815 -0.780589820737741 0.435465432810012 -17.7333397025469 16.4089608407297 -1.08071070890302 0.280420504803325 ASB2 other 1 1 1 -0.780589820737741 -1.08071070890302 0.000212514344918671 7.35269462857826 10.4507958991986 0.703553557020673 0.48208638020862 -20.2865030766028 12.1202201496681 -1.67377348151208 0.0948923238842115 CEP128 other 1 1 1 0.703553557020673 -1.67377348151208 2.02664119996498e-24 65.1782080938283 141.679481296869 0.460039855434372 0.645716416152158 -876.404962130287 161.40726829723 -5.42977383469743 9.37926577895166e-08 ERH essential 1.7879028666091e-20 0.0008517311253866 1 0.460039855434372 -5.42977383469743 1.00134255223364e-06 -191.050691883423 763.941415852715 -0.250085527396327 0.802639000172214 -2675.92013560261 873.842350871096 -3.06224587642737 0.0023327937933155 HIF1A other 0.00606813586653584 1 1 -0.250085527396327 -3.06224587642737 6.18021559584705e-05 -83.5127502271213 222.109641352931 -0.375997861769629 0.70710094808794 -672.006202813192 253.273963442477 -2.65327787222715 0.00826190466006442 SUSD6 other 0.314449369516698 1 1 -0.375997861769629 -2.65327787222715 1.19439304478166e-09 -241.679172801583 497.211448350919 -0.486069203762605 0.627161742507576 -2186.70203001156 566.975451519046 -3.85678431782705 0.000132172493643086 SRSF5 other 8.48257940403937e-06 1 1 -0.486069203762605 -3.85678431782705 4.89459874278437e-12 322.246254426595 351.381897651581 0.917082685762383 0.359608641119796 -1577.27533369653 407.605126992596 -3.86961603092196 0.000125745823790094 EIF5 essential 3.7159793655219e-08 0.991757312232469 1 0.917082685762383 -3.86961603092196 0.000149041672435531 -45.6946250117382 183.058467963622 -0.249617652327445 0.803000336904593 -509.155493248948 208.743499113495 -2.43914419089103 0.0151190655456941 SLC8A3 other 0.723150194657197 1 1 -0.249617652327445 -2.43914419089103 7.04698908588056e-20 -83.7664189811435 149.258331229072 -0.561217710873265 0.574936139279569 -1079.00721642862 174.98925124138 -6.16613425552774 1.5911600804071e-09 DICER1 other 6.00755819571318e-16 1.48614351510024e-05 1 -0.561217710873265 -6.16613425552774 7.43501814369117e-06 -296.593411984017 217.026435420303 -1.36662343188571 0.172449296478706 -1028.88928054605 254.269664544388 -4.04644919947358 6.15385524050157e-05 ZFYVE21 other 0.0418441297567093 0.497293041984932 1 -1.36662343188571 -4.04644919947358 1.13826208053809e-17 101.866793228913 156.149646024124 0.652366469106023 0.514507003188891 -749.123884105144 177.554809878808 -4.21911343667044 2.98262609770504e-05 MTHFD1 other 9.49310575168764e-14 0.246603525758253 1 0.652366469106023 -4.21911343667044 1.61183531321231e-27 18.5264437329632 106.30761329227 0.174272031505671 0.861732382987035 -794.853757189013 123.275849649119 -6.44776539323321 3.00990868498379e-10 ZC3H14 other 1.44533272535748e-23 2.83593596299173e-06 1 0.174272031505671 -6.44776539323321 6.33946505834537e-16 -128.035853161738 164.138711334784 -0.780046657613825 0.435784728018837 -973.289926858624 186.973167021408 -5.20550591490589 2.98052408165426e-07 PCNX1 other 5.17236954110399e-12 0.00267442425846837 1 -0.780046657613825 -5.20550591490589 5.08782856527811e-10 -11.4052597116899 26.5905326121972 -0.428921822591032 0.668191479239279 -138.83769448496 31.6950777859619 -4.3804181653232 1.48450498912764e-05 GSKIP other 3.66781561270899e-06 0.124460898288461 1 -0.428921822591032 -4.3804181653232 0.0536863430408677 44.8464961560199 28.7431051756514 1.56025230683878 0.119422486731826 4.54147344623556 34.2042620436228 0.132775074651327 0.894432243233136 VRK1 essential 1 1 1 1.56025230683878 0.132775074651327 6.73154038436064e-25 61.2045581081869 23.8613337157858 2.56500993771761 0.0106508954736641 -114.102846803025 27.9741257188775 -4.07887088053036 5.38090150273764e-05 PSMC1 other 5.95539377804386e-21 0.436875393007269 1 2.56500993771761 -4.07887088053036 0.000176435588343059 -218.945357939386 177.266245487636 -1.23512153899969 0.217447395558084 -644.483462340196 203.399476568201 -3.16856008291691 0.00163925303132863 PAPLN other 0.846714388458341 1 1 -1.23512153899969 -3.16856008291691 8.04155275282669e-09 -47.8540152669515 66.0895838519927 -0.724078023764235 0.469406168638685 -317.53428104671 77.4809300018649 -4.09822495727746 4.96559656614145e-05 RPS6KA5 other 5.51891765426496e-05 0.404298872415237 1 -0.724078023764235 -4.09822495727746 8.74044750459324e-19 81.9268299830029 93.7485688017177 0.87389952753606 0.382654054103739 -512.654076071034 109.907278480796 -4.66442334991133 4.12218525866794e-06 PPP4R3A other 7.38655218613175e-15 0.035529114744459 1 0.87389952753606 -4.66442334991133 5.52171381257988e-13 71.6374918005683 16.6437568616396 4.30416596421675 2.06961556281379e-05 -53.3534901580156 24.8186667599508 -2.14973232341838 0.0321234055094243 C14orf93 other 4.27656734784312e-09 1 0.177345357577514 4.30416596421675 -2.14973232341838 2.83161360879259e-21 650.097603899461 119.69277761745 5.43138539216826 9.28991612556951e-08 -562.380896257858 178.482249287541 -3.15090659436863 0.00173926165288186 PSMB5 essential 2.44962893296647e-17 1 0.000850398922134633 5.43138539216826 -3.15090659436863 6.25728768236898e-14 635.513978586374 204.753926707832 3.10379385052382 0.00203436202784767 -1125.44826936443 305.322861719121 -3.68609236474331 0.000256287041634002 ACIN1 essential 4.9432572690715e-10 1 1 3.10379385052382 -3.68609236474331 3.31653931418887e-10 308.673309042931 99.250103834261 3.11005527569411 0.00199264785316141 -306.572105446918 138.356189047942 -2.2158177928758 0.0272173857815524 CCNB1IP1 other 2.40316438706125e-06 1 1 3.11005527569411 -2.2158177928758 5.35635250091532e-15 -35.0237721971521 75.5336746810224 -0.463684208997602 0.643105408638894 -454.612282423961 88.5528251146262 -5.13379761555312 4.2865790060285e-07 TRIP11 other 4.30543614023574e-11 0.00382920102608526 1 -0.463684208997602 -5.13379761555312 2.12588632098076e-15 505.947028423765 236.790955499119 2.13668223668977 0.0331786108059188 -1466.51145564169 327.31053107811 -4.480489676917 9.52204581277641e-06 APEX1 other 1.72026721093763e-11 0.0807374264465312 1 2.13668223668977 -4.480489676917 8.33375062739732e-05 529.541891217576 256.707360775604 2.06282316805269 0.0397197225178042 -619.216085685764 382.829180879898 -1.61747357989418 0.106497645436911 PABPN1 essential 0.416937543888688 1 1 2.06282316805269 -1.61747357989418 3.8553712088072e-09 356.929303972106 281.794440440737 1.26663004214652 0.205962292577396 -1629.83373418709 417.526171386028 -3.9035486776234 0.000109757978100802 EFS other 2.68025406436277e-05 0.869283186558352 1 1.26663004214652 -3.9035486776234 0.000270817953258138 103.509398814565 325.844875362438 0.317664651621209 0.750891057593482 -1197.52136607395 443.764239017723 -2.698553107219 0.00723398449358481 ARHGAP5 other 1 1 1 0.317664651621209 -2.698553107219 7.45108127987083e-30 85.9314572013128 57.3222066162469 1.49909541648659 0.13457423291746 -426.411878258573 67.8794048337538 -6.28190360983447 8.12183536688065e-10 CINP essential 6.74024812577115e-26 7.61584502352399e-06 1 1.49909541648659 -6.28190360983447 0.327691228313848 -51.8579152988013 91.5740240748635 -0.56629503642219 0.571483268068752 -192.476235040133 135.817758470907 -1.41716545175765 0.157145467777808 DHRS2 other 1 1 1 -0.56629503642219 -1.41716545175765 4.52487857166643e-11 6.05095062566578 58.0272871557813 0.104277675594609 0.916996944299296 -385.971747987196 77.7107603195428 -4.96677353818311 9.79076166628144e-07 SRP54 essential 3.36198477874815e-07 0.00863349363732697 1 0.104277675594609 -4.96677353818311 0.778284160294129 -84.010650782098 149.330549157721 -0.562581810995466 0.574007501309631 -9.54182325940728 221.479187605106 -0.0430822569045188 0.965655595904846 CPNE6 other 1 1 1 -0.562581810995466 -0.0430822569045188 2.69328484388244e-21 325.815903941453 145.872590632479 2.23356493861369 0.0260159150133826 -1330.04581890187 216.114717895417 -6.15435094774762 1.70392558233061e-09 CHD8 other 2.33076870389586e-17 1.59061453110562e-05 1 2.23356493861369 -6.15435094774762 0.346533703144523 18.2471219120906 36.4737077460666 0.500281518926697 0.617128127158018 73.7016807208141 54.0958779439888 1.36242692644946 0.173763338126393 PCK2 other 1 1 1 0.500281518926697 1.36242692644946 3.55946613368397e-18 135.456554951984 73.410363335579 1.84519662888432 0.06568687167645 -515.659144921911 98.3119396022525 -5.24513245296705 2.44118243677494e-07 KIAA0391 other 2.98461235309401e-14 0.00219340241944228 1 1.84519662888432 -5.24513245296705 3.68149479236367e-27 386.065093064365 90.5528720577731 4.26342184727231 2.46744669152318e-05 -747.180005314668 134.303239704036 -5.5633803544965 4.61380630975745e-08 DCAF11 other 3.29420154020701e-23 0.000421701896711831 0.210942017658317 4.26342184727231 -5.5633803544965 2.56924190045219e-14 232.758002716074 90.5209162014357 2.57131735386017 0.0104617378775036 -451.596347851389 121.226574041801 -3.7252256893416 0.000220779324811957 PSMA6 essential 2.04434578018981e-10 1 1 2.57131735386017 -3.7252256893416 0.00104725357205659 234.466170336591 363.163896310746 0.645620813958796 0.518864576972311 -1049.7745295373 486.352953691441 -2.15846232981514 0.0314370405245884 NFKBIA other 1 1 1 0.645620813958796 -2.15846232981514 6.46913122611321e-08 116.464296855272 24.4511058209795 4.76315049748559 2.59563392731542e-06 19.3076166378654 36.2645894214006 0.532409630052824 0.59471229165705 EMC9 other 0.000421399208069015 1 0.0230128903995786 4.76315049748559 0.532409630052824 2.61055703058637e-14 27.9184692986702 40.9385175535618 0.681960924993025 0.495625766625561 -292.040389465516 54.8252982584121 -5.32674511115325 1.60560318872375e-07 BRMS1L other 2.0764370621284e-10 0.00144857519686657 1 0.681960924993025 -5.32674511115325 2.97204056401019e-09 526.851750620184 163.873976275792 3.2149811861129 0.00140106063589955 -507.156293996578 243.049230983855 -2.08664019196286 0.0374984396607311 REC8 other 2.07805076235593e-05 1 1 3.2149811861129 -2.08664019196286 5.97391262763338e-05 220.907351564938 74.3446597977388 2.97139501567343 0.00312772683429651 -62.6955160421938 110.264074883902 -0.568594223532972 0.569922952075699 TM9SF1 other 0.304370848377921 1 1 2.97139501567343 -0.568594223532972 1.50889000913105e-05 98.6754042167096 95.2690236825987 1.03575538409483 0.300891709654159 -322.0344797167 126.283530447923 -2.55009088338325 0.0111113009659458 SEC23A other 0.0824608389990116 1 1 1.03575538409483 -2.55009088338325 9.4774074336791e-33 247.07090123145 52.8033607878535 4.67907530022757 3.84649850868039e-06 -493.407081705514 78.3151573209657 -6.30027568843847 7.24466866307119e-10 GMPR2 other 8.66898457958627e-29 6.79912154029231e-06 0.033926116846561 4.67907530022757 -6.30027568843847 5.21840841068076e-09 338.111823175114 200.895201889321 1.68302587615503 0.0930892475560161 -824.715938055687 266.316839056984 -3.09674724653526 0.00208344647066308 PNN essential 3.60800757514468e-05 1 1 1.68302587615503 -3.09674724653526 5.80209169360726e-06 62.8953490099385 31.3964633891212 2.00326222193967 0.0457647469596427 -99.3763061773872 46.5655771328588 -2.13411520475417 0.0333881162241978 RABGGTA essential 0.0329964954615445 1 1 2.00326222193967 -2.13411520475417 0.10951403999769 114.075415500089 54.7836693326248 2.0822886982518 0.0378972659004943 131.147495085483 81.2601065759048 1.61392226286312 0.107266096173292 NFATC4 other 1 1 1 2.0822886982518 1.61392226286312 0.0809197017853573 8705.91512092295 4222.74440829207 2.06167228682546 0.0398324917775038 -2870.26100423751 11411.4179015004 -0.251525360740677 0.801526737742079 CST3 other 1 1 1 2.06167228682546 -0.251525360740677 0.0105544951500588 227.369616187111 77.1436161736437 2.94735491366287 0.00337747577406082 38.46703568535 208.470595772205 0.184520198365926 0.853691374337438 SYNDIG1 other 1 1 1 2.94735491366287 0.184520198365926 0.13173152232746 -375.319301324886 187.248578396665 -2.00439065833555 0.0456447489068508 -450.409036349239 336.088527415267 -1.34014998909117 0.180892953569162 CELF4 other 1 1 1 -2.00439065833555 -1.34014998909117 2.85476909600843e-08 147.144888471584 57.9025788072108 2.54124931052741 0.0113943841832384 -191.852298700807 86.3277796391708 -2.22237035983901 0.026775401133976 ZNF516 other 0.000190156169485122 1 1 2.54124931052741 -2.22237035983901 5.23562230767032e-06 -13.778598706792 198.62355480241 -0.0693704164166175 0.944726435331314 -1241.48171203602 319.815005196147 -3.88187449577171 0.000119619565126897 CDH20 other 0.0299372883552589 0.944516086241982 1 -0.0693704164166175 -3.88187449577171 1.39874366068758e-09 77.8938822847191 57.9029975009284 1.34524783943129 0.179283376216358 -329.608328501017 87.0161299449134 -3.78789919420318 0.000174494764814509 ADNP2 other 9.89471265570396e-06 1 1 1.34524783943129 -3.78789919420318 4.54642106544623e-12 134.980221617286 29.2341280138545 4.61721387938497 5.19795149565634e-06 -51.1822819125513 43.9286383644929 -1.16512334135814 0.244639948468344 RBFA other 3.45346144131295e-08 1 0.0456224202773757 4.61721387938497 -1.16512334135814 8.90777603041529e-19 270.15921783797 48.3772479328571 5.58442717148616 4.14713272929241e-08 -331.130670219512 93.8547027263531 -3.52812017512826 0.000463282484314657 USP14 other 7.52617996809788e-15 1 0.000382033867022417 5.58442717148616 -3.52812017512826 2.60419757902074e-19 340.482799265594 172.070536455266 1.97873968594333 0.0484727235684104 -1791.75383837867 286.639882923053 -6.25088811824437 9.71206176727378e-10 VAPA other 2.21070332483071e-15 9.09579360053748e-06 1 1.97873968594333 -6.25088811824437 1.40706852093444e-32 115.629305584828 10.2358427344157 11.2965105643965 4.00296437028214e-26 6.7374192008834 19.8543062301163 0.339342967857706 0.734515142561556 METTL4 other 1.28648274869036e-28 1 3.93051071518003e-22 11.2965105643965 0.339342967857706 2.93777666798258e-05 169.275681258305 112.201690834075 1.50867317595625 0.13210329313598 -626.858171976488 218.499967181363 -2.86891654979597 0.00431796924210566 LPIN2 other 0.155760918936437 1 1 1.50867317595625 -2.86891654979597 2.27126052634919e-11 421.93910041473 85.4642895606692 4.93702226489819 1.13246887843956e-06 -289.943367897038 165.77376389065 -1.74903049247464 0.0809910290188504 SMCHD1 other 1.69731299134075e-07 1 0.0101378613997909 4.93702226489819 -1.74903049247464 0.223536542680612 -28.086656727225 41.1177112647317 -0.683079282949197 0.494918717642381 -136.989663094072 80.0796431021738 -1.71066775259333 0.0878521630404393 MYOM1 other 1 1 1 -0.683079282949197 -1.71066775259333 0.744006092415637 -28.7176244690542 104.546641970203 -0.274687201117747 0.783686376301958 94.8537597703609 205.552732879588 0.4614570599065 0.644700326975841 MYL12A other 1 1 1 -0.274687201117747 0.4614570599065 5.65758060293111e-12 39.4104632942776 9.60074498733034 4.10493803827576 4.83072642301645e-05 -30.0978507448725 15.0608918997304 -1.99841091385904 0.0462940721268703 CEP76 other 4.28618306478061e-08 1 0.407520081045668 4.10493803827576 -1.99841091385904 0.464215164802384 -157.734413774563 185.324188628546 -0.851126962658484 0.395163898750694 -360.024148422376 290.648249397481 -1.23869367583914 0.21612238374996 ST8SIA5 other 1 1 1 -0.851126962658484 -1.23869367583914 2.71784892582802e-08 212.118205134204 64.6807145291552 3.2794660151534 0.00112361099867981 -170.978476266206 101.466006107492 -1.685081366907 0.092690076962534 CEP192 essential 0.000181226166374212 1 1 3.2794660151534 -1.685081366907 1.31114947948534e-11 78.0749900605737 80.5854110208457 0.968847699248905 0.333159547803929 -611.67558876494 126.416040180418 -4.83859158926327 1.81873775949326e-06 RNMT essential 9.8585329362503e-08 0.0158903118046926 1 0.968847699248905 -4.83859158926327 7.18226280575995e-06 -78.082313529114 41.9235546490156 -1.86249267703609 0.0632029909384527 -307.482308887048 65.7496890040565 -4.67655913730751 3.89169643125872e-06 SMAD7 other 0.0404720509104573 0.0335658817196065 1 -1.86249267703609 -4.67655913730751 0.00115279727716589 34.2467319985202 56.0179661108797 0.611352649447029 0.541283300556485 -204.680324743264 87.1641918730885 -2.34821571042934 0.0193074655323707 LIPG other 1 1 1 0.611352649447029 -2.34821571042934 0.0104292619559495 -12.0736413092572 62.7199875129043 -0.192500696955227 0.847439242875014 -254.054935025029 102.737466187628 -2.47285575995278 0.0137824163328679 LAMA1 other 1 1 1 -0.192500696955227 -2.47285575995278 0.495730604844076 -10.3199233193089 12.3494963493132 -0.835655400625539 0.403805449507229 -32.8076498551996 29.1829672073604 -1.1242054182525 0.261543035219444 RNF125 other 1 1 1 -0.835655400625539 -1.1242054182525 1.63050229213439e-08 87.8482741417988 81.4122460290429 1.07905479122219 0.281157160424725 -540.808600861106 134.450638707641 -4.02235798996151 6.78590768914417e-05 ANKRD12 other 0.000110270870017049 0.546740582514345 1 1.07905479122219 -4.02235798996151 6.92747316692096e-09 156.88525006777 36.3853222217407 4.31177300318174 2.003418879855e-05 -151.437838845215 78.8786679013217 -1.91988332047728 0.0555233256061171 NOL4 other 4.76887252810839e-05 1 0.171833237325164 4.31177300318174 -1.91988332047728 5.53369840390828e-12 51.8121729432958 36.8063017999224 1.40769842145361 0.159929686875022 -259.483068113581 57.2458503178983 -4.53278389040632 7.52083922115326e-06 POLI other 4.19439455110015e-08 0.0640775501642257 1 1.40769842145361 -4.53278389040632 5.23104641746046e-06 112.934970929044 207.169837012098 0.545132305734494 0.585949152607842 -1220.12024073746 339.916457303295 -3.58947092593633 0.000370082673016846 MIB1 other 0.0299215855078738 1 1 0.545132305734494 -3.58947092593633 1.05432465664537e-10 180.009822350195 55.2810216523612 3.25626800970142 0.00121929042905171 -259.271453794751 90.6967428966404 -2.85866333800125 0.00446360597957546 RIOK3 other 7.75350352497008e-07 1 1 3.25626800970142 -2.85866333800125 0.0176883621080541 322.943775100405 120.619977115129 2.6773655809283 0.00769975596071596 156.348244653266 192.076715919234 0.813988535284038 0.416094831025211 EEA1 other 1 1 1 2.6773655809283 0.813988535284038 0.254167342275693 26.8662126077184 58.1200380152375 0.462253871903436 0.644129858510882 93.5307478786039 69.0620379683233 1.35430043233742 0.176342003408361 RUBCNL other 1 1 1 0.462253871903436 1.35430043233742 1.14130650142763e-06 171.037406893896 131.644517265956 1.29923684211137 0.194547691194569 -505.707724085521 174.264594155066 -2.90195335740734 0.00389592907881082 NALCN other 0.00688207820360861 1 1 1.29923684211137 -2.90195335740734 0.00171727574273742 32.4155645107668 108.623380462385 0.29842161395439 0.765523237451214 -353.351081461607 144.866130908957 -2.43915592446985 0.0151185813804234 FGF14 other 1 1 1 0.29842161395439 -2.43915592446985 0.0026924574706694 -71.6941906388261 61.2725197764245 -1.17008719243845 0.242605073787405 -214.634684741114 72.8080233895384 -2.94795373846056 0.00337066966307795 HTR2A other 1 1 1 -1.17008719243845 -2.94795373846056 2.67225260696901e-09 83.6198343381273 141.747405384511 0.589921445907922 0.555553892388959 -611.067656000411 165.312528999072 -3.69643885856856 0.000246979258060931 NDFIP2 other 1.87271462696388e-05 1 1 0.589921445907922 -3.69643885856856 0.0323867924600257 308.243759681656 133.207841568291 2.31400611294816 0.021131471919793 94.6845381097714 188.146926694657 0.503247859389351 0.615044156434379 TNFSF13B other 1 1 1 2.31400611294816 0.503247859389351 1.3888042438629e-08 514.887272207989 259.798857918177 1.98186888246503 0.0481228951978046 -641.462726866437 308.750946050102 -2.07760570476874 0.0383317482942696 FNDC3A other 9.42720320734136e-05 1 1 1.98186888246503 -2.07760570476874 4.22982904843191e-20 21.6699989229068 14.8857566961247 1.45575393749034 0.146181963364309 -86.2236852734469 17.5339823498577 -4.91751865337921 1.24470156800539e-06 CDADC1 other 3.61734980221897e-16 0.0109434161859034 1 1.45575393749034 -4.91751865337921 4.63746489619338e-06 432.415251635835 231.92924642563 1.86442744198926 0.062934996343416 -384.41652799095 273.190231189355 -1.4071386312657 0.160100372052049 CAB39L other 0.0266607856882158 1 1 1.86442744198926 -1.4071386312657 0.582007624931247 -2.07989773770509 9.84004625763539 -0.211370727662097 0.832697213702366 5.55336851512964 11.4261567025646 0.486022436037761 0.627196556949396 KLF5 other 1 1 1 -0.211370727662097 0.486022436037761 2.2058098825971e-11 455.516902993837 159.201244550048 2.86126471109738 0.00442205243530532 -614.244853114233 210.742846315789 -2.91466526077861 0.00374365681393395 STK24 other 1.64972521119437e-07 1 1 2.86126471109738 -2.91466526077861 4.53926144738189e-08 268.460298689061 88.4423015312908 3.03542868108289 0.00254578960751331 -196.693911229054 117.089662339244 -1.67985719063031 0.0937014381135929 DNAJC3 other 0.000298501832779833 1 1 3.03542868108289 -1.67985719063031 1.96688374492814e-18 159.602455294006 30.1032306403205 5.30183810505154 1.82563562878263e-07 -86.1601896691164 39.8539731550116 -2.16189711710793 0.0311695100444736 UGGT2 other 1.65611611322949e-14 1 0.00166388431207249 5.30183810505154 -2.16189711710793 3.89620204115609e-18 1406.21701675788 266.542153859889 5.27577719469122 2.08710815254127e-07 -893.073745358126 368.986775588231 -2.42034079387915 0.0159137202572661 ARHGEF7 other 3.26540693069292e-14 1 0.00189968584044307 5.27577719469122 -2.42034079387915 0.0023605869925349 8.9145110745202 19.0410833748262 0.468172472071934 0.639896284287431 -45.0024078893792 23.4729918891229 -1.91719948193876 0.0558687894880847 FGF9 other 1 1 1 0.468172472071934 -1.91719948193876 0.807966855716482 1.09882629107985 13.9610287205195 0.0787066850929707 0.937302120129101 -6.22112676056339 17.1752925809759 -0.362213728309594 0.717368221568612 SGCG other 1 1 1 0.0787066850929707 -0.362213728309594 0.000107659297991162 15.9289525318543 100.634686041858 0.158284913068928 0.8743054127945 -330.273384103833 123.542598178636 -2.673356307646 0.0077908686133493 PARP4 other 0.531406294884373 1 1 0.158284913068928 -2.673356307646 3.44112073293738e-18 218.670853243595 74.9927546098947 2.91589306701829 0.00372924053533575 -310.88346822283 90.1418954687479 -3.44882328695443 0.000617655737610594 SUPT20H other 2.88641207078787e-14 1 1 2.91589306701829 -3.44882328695443 1.36781170689182e-28 96.1061107661286 21.3507436035003 4.50130040203249 8.66821954667703e-06 -97.7537267660467 25.8176453881745 -3.78631456495339 0.0001742209984448 MRPS31 essential 1.23116731737333e-24 1 0.0754828558124636 4.50130040203249 -3.78631456495339 2.75991492287195e-07 20.0289468036609 12.2639236486025 1.63315977639369 0.103153999187909 -32.0246673244619 14.8297238591426 -2.15949181715333 0.0313541566159943 SLC25A15 other 0.00173460652902502 1 1 1.63315977639369 -2.15949181715333 2.17281804340463e-20 234.635926434553 87.0287346900097 2.69607420204728 0.00728839262823986 -392.577704176426 102.51143620951 -3.82959910320723 0.000147214876204661 KPNA3 other 1.86167049958908e-16 1 1 2.69607420204728 -3.82959910320723 0.0064539491502766 -302.519127502817 141.56837199479 -2.13691182034607 0.0331649493557148 -546.368663066947 172.172305652734 -3.17338297234025 0.00161411926423111 FLT1 other 1 1 1 -2.13691182034607 -3.17338297234025 0.000215648235284466 -160.895211173904 518.989807282441 -0.310016129249997 0.75669613940121 -1808.11408304223 627.570404728122 -2.88113344641474 0.00415710866023642 RGCC other 1 1 1 -0.310016129249997 -2.88113344641474 1.32169678421961e-06 124.493420876734 39.5442911607156 3.14820211015463 0.00175507088144979 -10.2791572610983 47.3331665222353 -0.217166059580432 0.82818005514216 DGKH other 0.00792621561496503 1 1 3.14820211015463 -0.217166059580432 6.77660339373477e-05 120.749350446079 61.9047150628026 1.95056790623426 0.0517547219881693 -88.1069695682314 75.2965251569865 -1.17013327486941 0.242592466104261 KATNAL1 other 0.342963897756917 1 1 1.95056790623426 -1.17013327486941 7.46652379425148e-20 48.809581499104 34.4523931752522 1.41672542893667 0.157277313553247 -196.318694602719 39.9780546869456 -4.91066151517434 1.28566102253698e-06 INTS6 other 6.36297157746111e-16 0.011298389066055 1 1.41672542893667 -4.91066151517434 7.85950967272389e-18 28.6454863767626 20.9399922400615 1.36797979905452 0.172023012440557 -111.457831896456 24.2984616673518 -4.58703243943276 5.88430916506167e-06 DHRS12 other 6.56269057672445e-14 0.0503696864529279 1 1.36797979905452 -4.58703243943276 0.828011990032556 -3.25643923203518 36.4901362426817 -0.0892416298579394 0.928931143370846 -20.7008823753289 44.300128054213 -0.467287190456782 0.640529482695562 MEDAG other 1 1 1 -0.0892416298579394 -0.467287190456782 2.04791026572079e-11 3087.3108718669 1439.10810519715 2.14529461735186 0.0324797808751031 -4688.12678079106 1727.39911883672 -2.71398006961367 0.00691097959657671 TSC22D1 other 1.53265604286544e-07 1 1 2.14529461735186 -2.71398006961367 9.75857176179174e-15 91.0308479009155 72.7991682099091 1.25043802201747 0.211813340052403 -365.45401189257 84.6362178009289 -4.31793883739166 1.95331611723508e-05 CLN5 other 7.80880912378575e-11 0.1627698320492 1 1.25043802201747 -4.31793883739166 0.0113040049624174 50.3179481032474 23.3462358489312 2.15529168936889 0.0316882737675493 11.5255657783052 27.2889109099719 0.422353453984621 0.67297620376055 OLFM4 other 1 1 1 2.15529168936889 0.422353453984621 0.0904835897465946 17.6600241998524 16.4358840347905 1.07447972755653 0.283199281259306 82.4489358132818 37.9335390467711 2.17351024674034 0.0302769908705298 TRADD other 1 1 1 1.07447972755653 2.17351024674034 0.901892107323274 -34.8266712464007 78.1465414593848 -0.445658510229799 0.656064639908699 -13.3462031113564 180.362964272099 -0.0739963615325263 0.941047138802235 HSF4 other 1 1 1 -0.445658510229799 -0.0739963615325263 0.0453358488920952 13.8228500279081 5.75061816961078 2.40371549983185 0.0166449528072703 2.91006540437674 13.2724816747912 0.2192555601643 0.82655334750477 ELMO3 other 1 1 1 2.40371549983185 0.2192555601643 1.69111738483611e-08 470.92762530919 87.93012468546 5.35570291744464 1.37912289540738e-07 -173.160986126131 202.9401528438 -0.853261336899707 0.393980765460212 NUTF2 essential 0.000114268801693376 1 0.0012590012912174 5.35570291744464 -0.853261336899707 5.56427572898423e-11 368.634135428757 55.9068059902723 6.59372555629272 1.23997111929025e-10 -38.0576404133054 128.844651949512 -0.295376174621656 0.767846820715306 NUP93 essential 4.12090260488572e-07 1 1.17871654599732e-06 6.59372555629272 -0.295376174621656 6.26987497776317e-05 363.366424311216 88.2552841452676 4.11722003764802 4.5841033619327e-05 -24.7152519747139 203.690611355123 -0.121337217313488 0.903479587454879 CENPT essential 0.31876044386948 1 0.387035846847978 4.11722003764802 -0.121337217313488 0.143625516209914 41.1352514750134 26.1795985404136 1.57127128636112 0.116841720343608 -34.0464936984007 60.4217467925345 -0.563480791366451 0.573395892725164 TSNAXIP1 other 1 1 1 1.57127128636112 -0.563480791366451 0.0149070518983908 103.143746511527 85.2628750132348 1.20971462075982 0.227042413955105 -404.008175547066 196.787530101266 -2.05301715682474 0.0406657343622985 NFAT5 other 1 1 1 1.20971462075982 -2.05301715682474 5.04369427542192e-06 485.376683291774 113.987539056764 4.2581556484877 2.52504411727282e-05 -300.562177888608 276.047647130038 -1.08880543273394 0.27683977756207 ARL2BP other 0.0288902808096167 1 0.215714518938617 4.2581556484877 -1.08880543273394 0.0466821958532745 403.523690773067 223.19052676127 1.80797857610097 0.0712972035289954 -547.936824605152 540.508377354132 -1.01374344517542 0.311266128921349 PLLP other 1 1 1 1.80797857610097 -1.01374344517542 0.608251477554538 16.3933199075819 114.139964413646 0.143624715425459 0.885862876624839 -267.003668664918 291.628709061055 -0.915560301057391 0.360401341551846 ZNF423 other 1 1 1 0.143624715425459 -0.915560301057391 3.96412354960007e-08 95.3851959859345 18.5539256354938 5.14097112707307 4.13133568640518e-07 -49.8625486358555 44.2818192738196 -1.12602755382581 0.260771851816334 DHODH essential 0.000261513230567117 1 0.00373927192976533 5.14097112707307 -1.12602755382581 4.75831050674215e-05 214.701292443435 80.3900695121034 2.67074395813415 0.00785010593592997 -456.371731859921 185.537926305337 -2.45972206840815 0.014289840569767 CTCF other 0.245471397467907 1 1 2.67074395813415 -2.45972206840815 3.35926370385646e-05 183.40575442504 44.5409619204362 4.11768732683992 4.57516820497773e-05 -46.1394810952029 102.799235782704 -0.448830973731478 0.653775567581839 ACD other 0.176798048733966 1 0.386372954910369 4.11768732683992 -0.448830973731478 7.70350554838961e-10 240.761418475047 49.6135926676214 4.85273098620354 1.696161037863e-06 -295.217181938003 116.169117276925 -2.54127076849746 0.0113888903645896 POLR2C essential 5.50954716820825e-06 1 0.0151195794915108 4.85273098620354 -2.54127076849746 0.0198261846439453 61.4318709912303 25.8129969423228 2.37988138798819 0.0177453598623551 -33.4870702116945 59.5756410396375 -0.562093325851324 0.574339965231097 PARD6A other 1 1 1 2.37988138798819 -0.562093325851324 0.0029160046595784 106.98872115962 40.473261709884 2.64344203159422 0.00850185384769072 -115.754859687013 96.5957121780492 -1.19834366429898 0.23143273364367 ZNF821 other 1 1 1 2.64344203159422 -1.19834366429898 0.165146285788533 152.560968411736 101.671613680474 1.50052667493991 0.134198509696854 -133.793683751943 236.368843189375 -0.566037731312791 0.571658011902257 MMP15 other 1 1 1 1.50052667493991 -0.566037731312791 1.64999760886511e-06 202.361373146287 51.0160940147302 3.96661832024729 8.51454893740022e-05 -214.67074211874 118.603557962591 -1.80998568513814 0.0709832473984737 USB1 other 0.00983265215970543 1 0.710453963336675 3.96661832024729 -1.80998568513814 0.0323414483581685 29.5405092095649 83.3678568935991 0.3543393138589 0.72325552455348 -445.011749889086 192.413810176828 -2.31278487484927 0.021198136020653 CYB5B other 1 1 1 0.3543393138589 -2.31278487484927 0.722638042243059 -14.2735654092018 61.9939966083245 -0.230241090913716 0.818011926761699 -115.07617599503 143.080328750765 -0.804276709452381 0.421673494902345 CCDC113 other 1 1 1 -0.230241090913716 -0.804276709452381 0.517689810794953 -6.38453136879066 9.25336349407994 -0.689968720333457 0.490579265995772 -23.5460136275861 21.3564919704742 -1.10252253320157 0.270839991926519 PRSS54 other 1 1 1 -0.689968720333457 -1.10252253320157 0.501198046530412 -1033.09279465462 1167.98882079456 -0.88450572151181 0.376908550357703 -2797.88101382386 2695.68399521549 -1.03791134969446 0.299883965684904 NDRG4 other 1 1 1 -0.88450572151181 -1.03791134969446 8.11277321730429e-06 222.526143841693 63.3829606432461 3.51081965221207 0.000493048894722543 -312.938269108105 151.271414163698 -2.06872045745179 0.0391585259505642 PSMD7 essential 0.0455451088419463 1 1 3.51081965221207 -2.06872045745179 6.78428681101321e-12 274.766557089165 38.8866256731219 7.06583696407171 6.32418276405225e-12 42.9839238739745 89.7491933044868 0.47893381869345 0.632224716307764 SETD6 other 5.12959925780709e-08 1 6.06615610727892e-08 7.06583696407171 0.47893381869345 0.000986183904804374 63.777682596452 35.2730632065479 1.80811295642202 0.0712746836266466 -198.238357836573 81.4091969505591 -2.4350855340947 0.0152864476775459 SLC38A7 other 1 1 1 1.80811295642202 -2.4350855340947 6.3831835759784e-10 246.577902580938 44.0024298928848 5.60373377518431 3.71494631366675e-08 -162.563006580687 105.017337924636 -1.54796350577224 0.122353292166657 VAC14 other 4.5805725341221e-06 1 0.000342406601730664 5.60373377518431 -1.54796350577224 0.0209009534090147 45.6878059802663 18.238656140389 2.50499848391197 0.0126090011120042 -11.4476305246807 42.095704266436 -0.271942962451117 0.785794602248971 HAS3 other 1 1 1 2.50499848391197 -0.271942962451117 0.00113317211658818 54.059877984484 30.5971073890063 1.76682969723824 0.0779563387760184 -171.575872346376 70.6196100272835 -2.429578303818 0.0155192995437905 TANGO6 essential 1 1 1 1.76682969723824 -2.429578303818 9.03054346427137e-05 351.098119136892 100.11954039667 3.50678916169464 0.000500368110321505 -306.459037943962 238.947886112001 -1.28253504532079 0.200333342129171 COG4 essential 0.449811369955357 1 1 3.50678916169464 -1.28253504532079 0.150511041645932 -12.9836811615918 80.7472210488486 -0.16079415480735 0.872329663768356 -349.466882252365 186.362221593382 -1.87520238417664 0.0614299794499723 SMPD3 other 1 1 1 -0.16079415480735 -1.87520238417664 3.49404133502849e-08 179.662615511463 42.1360048012241 4.26387400416861 2.46265579522768e-05 -234.561772085932 97.2486651779021 -2.41197934857857 0.0162764439720811 SLC7A6OS essential 0.000231340476792236 1 0.210557070491967 4.26387400416861 -2.41197934857857 1.52216705549059e-05 192.606388332673 52.8947430401965 3.64131437761792 0.000303677570845318 -194.952017903605 122.07951797646 -1.59692650442146 0.11100326890992 SLC7A6 other 0.0831255429003411 1 1 3.64131437761792 -1.59692650442146 0.235060321929109 79.9626080159333 50.9861571648716 1.5683199609918 0.117528605295966 138.694457234433 117.674557666902 1.17862739392683 0.239186473551751 PLA2G15 other 1 1 1 1.5683199609918 1.17862739392683 0.179932136114714 -173.233624945121 157.975073741436 -1.09658834677083 0.273423922122512 -651.888602155134 364.601844081075 -1.78794653054519 0.0744757966094363 FA2H other 1 1 1 -1.09658834677083 -1.78794653054519 6.03100478267241e-10 273.745451819807 53.2814065957395 5.13772945029001 4.19528004629019e-07 -267.452280247135 122.971926139666 -2.17490518887518 0.0301715708010332 WDR59 other 4.33388003682839e-06 1 0.00379588938588337 5.13772945029001 -2.17490518887518 1.0547314506815e-07 64.3067279206582 66.8786762875298 0.961543073074382 0.336810909129161 -769.713283385572 154.356623806343 -4.9865905615509 8.88003379264214e-07 MON1B other 0.000678719688513545 0.00784550985579933 1 0.961543073074382 -4.9865905615509 1.88588226357197e-05 133.66523894677 33.3135752811594 4.01233544639578 7.06989964879542e-05 -70.242034215307 76.8867562000609 -0.913577808283858 0.361441340283507 CMC2 other 0.101875359878158 1 0.592245493579592 4.01233544639578 -0.913577808283858 0.000617250067585675 8.38248616004054 25.3753827204511 0.330339299800383 0.741301549390599 -204.825700385838 58.565640230575 -3.49736978165751 0.000517871589144924 MLYCD other 1 1 1 0.330339299800383 -3.49736978165751 0.522985894186106 94.9339965092252 86.3007268583488 1.10003704447411 0.271920200443427 22.0440915596776 199.179550373825 0.110674471944056 0.911925183912553 NECAB2 other 1 1 1 1.10003704447411 0.110674471944056 3.09875083289284e-08 309.246720705864 64.1540559972835 4.82037676182093 1.97939461932922e-06 -242.399672338281 148.065682565685 -1.63710907306795 0.102325910506039 HSDL1 other 0.000205973967862387 1 0.0176146327174107 4.82037676182093 -1.63710907306795 0.0149504874931096 302.657486427739 162.427709453221 1.86333654181649 0.0630839702833087 -538.656280004417 374.878396913677 -1.43688269166509 0.151465249853734 TAF1C essential 1 1 1 1.86333654181649 -1.43688269166509 0.893960899593149 6.52527185388514 45.9543846042051 0.141994543286476 0.887149605240078 48.5839975717903 102.904767466806 0.472125818538604 0.637072112009859 WFDC1 other 1 1 1 0.141994543286476 0.472125818538604 0.942568721864177 -172.556191934119 563.154571477949 -0.306409999445197 0.759438095511929 38.8465213260169 1261.06117457406 0.0308046287596934 0.975439380434532 COTL1 other 1 1 1 -0.306409999445197 0.0308046287596934 1.00629634416211e-07 271.151116448478 73.7436849484748 3.67694015613586 0.000265367715330564 -457.568874049833 165.132811964014 -2.770914324099 0.00582785271572417 USP10 essential 0.000648859882715731 1 1 3.67694015613586 -2.770914324099 0.466660343519458 -72.6685758023643 74.4683333926392 -0.975831907224437 0.329686404484379 -177.960436021961 166.755503254174 -1.06719378100948 0.286472198797836 CRISPLD2 other 1 1 1 -0.975831907224437 -1.06719378100948 0.512632078859795 -4.81764999081837 14.6200532278602 -0.329523423460441 0.741917616442889 -35.368853677519 30.8434763156933 -1.14672073003403 0.252123099389856 FOXF1 other 1 1 1 -0.329523423460441 -1.14672073003403 1.33295535688015e-07 70.8960692527455 17.8519912984631 3.97132555508522 8.3537794871005e-05 -81.7139193887036 37.9322973349905 -2.15420433587414 0.0317689271647009 MTHFSD other 0.000852291655189166 1 0.697289973788279 3.97132555508522 -2.15420433587414 0.284791191746744 -490.083278835225 601.840334730685 -0.814307799849491 0.41591113979135 -2015.3462751982 1278.80336392276 -1.57596260070514 0.115756389514936 SLC7A5 essential 1 1 1 -0.814307799849491 -1.57596260070514 0.197570418202566 -15.6643375899215 91.7779331894602 -0.170676512812564 0.864556944846933 -333.443445312591 195.011738036933 -1.70986346088275 0.087999346754325 FBXO31 other 1 1 1 -0.170676512812564 -1.70986346088275 0.222480998706751 169.820535274016 250.824674808036 0.67704876086846 0.49873243674363 -835.06202921221 615.768914075843 -1.35612891479832 0.175756840963217 SALL1 other 1 1 1 0.67704876086846 -1.35612891479832 0.00929958794544916 223.533599156623 95.8320184417912 2.33255651703087 0.0201235858028418 -305.169305061973 235.265441786221 -1.29712763058194 0.195270109554711 TOX3 other 1 1 1 2.33255651703087 -1.29712763058194 0.000312215112374528 268.359478588761 119.405825793761 2.24745716387637 0.0251077866078857 -722.145930241537 282.416369644464 -2.55702575297123 0.0108931613111333 RBL2 ts 1 1 1 2.24745716387637 -2.55702575297123 0.0268804930779476 58.6323618043864 25.2994131341444 2.31753841456724 0.0209345127194773 -38.0900261169231 59.8376868463803 -0.636555791581828 0.524746748313576 RPGRIP1L other 1 1 1 2.31753841456724 -0.636555791581828 0.843191752219615 -7.1205075350587 16.981881610593 -0.419300269448177 0.675203206932024 -15.1656858451977 26.141702651741 -0.580133820938695 0.562124059273589 AQP9 other 1 1 1 -0.419300269448177 -0.580133820938695 3.61114489335127e-06 74.8560596915847 53.1593822420627 1.40814389735993 0.159799462779966 -294.408772671031 92.2281618670333 -3.1921786871941 0.00151398448824392 AAGAB other 0.0209482515263307 1 1 1.40814389735993 -3.1921786871941 0.230878410899192 9.0013730874855 10.2348354962976 0.879483904821107 0.379622313413567 -12.4778344448802 17.7567914641434 -0.702707720033593 0.482612068566838 IQCH other 1 1 1 0.879483904821107 -0.702707720033593 0.00018978243431299 5.27073374060568 19.2405841667961 0.273938342771395 0.784261439410111 -100.757115316981 31.9080529830558 -3.1577331080178 0.00170019576265425 LACTB other 0.90697025358178 1 1 0.273938342771395 -3.1577331080178 0.00150705875587533 46.2268461236608 287.64689442917 0.160706918861047 0.872398502749666 -1437.94245103661 499.049146567613 -2.8813644125565 0.00415457128950585 CORO2B other 1 1 1 0.160706918861047 -2.8813644125565 1.5922092775803e-06 254.571087406465 110.685670457548 2.29994620219699 0.021923899475199 -489.155101174362 192.051025789686 -2.54700592804974 0.0112085208180452 CSK other 0.00949593613148892 1 1 2.29994620219699 -2.54700592804974 0.00811107319258556 -113.42263610314 212.418754986547 -0.533957729440244 0.593642283671617 -996.35358848409 357.223379123813 -2.78916119915756 0.00551540988678583 HERC1 other 1 1 1 -0.533957729440244 -2.78916119915756 0.0969695844656975 -58.9126762687584 33.2646442313588 -1.77102980146173 0.0772543220929258 -116.236464965295 56.789444481116 -2.04679700650966 0.041277061259104 TRIP4 other 1 1 1 -1.77102980146173 -2.04679700650966 1.89269526579451e-13 35.2962876488438 9.87553356593639 3.57411449347821 0.000390754517621877 -62.9274924118614 16.9720502356365 -3.70771306578692 0.000236175737149753 MTFMT other 1.4810340454842e-09 1 1 3.57411449347821 -3.70771306578692 0.111456322256439 -221.119308895634 262.460711562002 -0.842485366970434 0.399979291312195 -927.912806444084 451.063869285611 -2.05716500395764 0.0402659969103405 RASL12 other 1 1 1 -0.842485366970434 -2.05716500395764 0.140186620133024 -272.483095063082 148.598079774558 -1.8336918988218 0.0673812136283585 -464.218730592102 291.338678811727 -1.59339890084453 0.111795386974497 AP3B2 other 1 1 1 -1.8336918988218 -1.59339890084453 0.00491971193848485 -521.220691598106 274.243783426712 -1.90057431780362 0.0580185848946594 -1647.17407699032 502.629005852249 -3.27711703425751 0.00113277130312326 ACSBG1 other 1 1 1 -1.90057431780362 -3.27711703425751 0.0280255810389308 403.85594209666 192.284739823309 2.10030157602607 0.0362775103080766 -50.6460891898221 330.459740938369 -0.153259483427567 0.87826471857412 IGDCC4 other 1 1 1 2.10030157602607 -0.153259483427567 9.09922752329751e-13 248.661246307393 140.464273450152 1.77028108429036 0.0773790847333957 -1228.39514535594 241.389634850637 -5.0888479371371 5.36544729074778e-07 RAB11A other 7.01186472945306e-09 0.00477310190984922 1 1.77028108429036 -5.0888479371371 0.0694470065906825 -419.84974337225 677.928367298545 -0.619312841333511 0.536033019507708 -2746.53626933693 1242.38649402559 -2.21069392056701 0.0275742707455653 CTSH other 1 1 1 -0.619312841333511 -2.21069392056701 4.20120733216409e-09 116.883026894835 29.350431572783 3.9823273673162 7.99199558806807e-05 -107.092141715332 54.1746056685025 -1.97679596175808 0.048692906991766 TTC23 other 2.91521776778866e-05 1 0.667811151338968 3.9823273673162 -1.97679596175808 0.00533067854790572 458.957550327559 231.377244194433 1.98358983799584 0.0479269588593028 -417.832492548488 408.50311387328 -1.02283796220486 0.306950342464511 CD276 other 1 1 1 1.98358983799584 -1.02283796220486 0.00750299493645575 25.921347547299 39.2609254705127 0.660232718323654 0.509452343564662 -159.98554761631 71.9504388669869 -2.22355207467284 0.0266891649266798 FAH other 1 1 1 0.660232718323654 -2.22355207467284 0.229111930040832 -142.362580819371 109.24499639574 -1.30314966832588 0.193211436280238 -349.095378107142 214.183742919241 -1.62988737309894 0.103847496774195 CEMIP other 1 1 1 -1.30314966832588 -1.62988737309894 3.41082036967333e-08 54.773441344373 59.7653083784362 0.91647550779033 0.359924180575345 -371.135449940127 92.0796991260151 -4.0305892988661 6.56565205314349e-05 RPAP1 essential 0.000226000957694555 0.529519838086023 1 0.91647550779033 -4.0305892988661 0.498852491046929 -50.0197476785534 78.8100411971928 -0.634687495637739 0.52596514657292 -182.277631598687 154.513526112328 -1.17968721693773 0.23876791508476 HOMER2 other 1 1 1 -0.634687495637739 -1.17968721693773 0.900764627493138 -29.9316276177746 126.444714416019 -0.236717111948988 0.812987432886741 28.1828758152649 191.165365327886 0.147426683525678 0.882863394523829 EHD4 other 1 1 1 -0.236717111948988 0.147426683525678 7.61950666999615e-08 -22.657139873476 140.608451768286 -0.161136401038066 0.872060779521649 -988.526365400146 214.552251054833 -4.60739218787087 5.36420211610473e-06 TMEM87A other 0.00049511554341635 0.0459873047413659 1 -0.161136401038066 -4.60739218787087 6.02783792669902e-05 -104.756940836289 277.709070459701 -0.377218290576112 0.706195348232512 -1535.51091106242 419.920336880627 -3.65667193560794 0.00028678835686583 ZNF106 other 0.307058063986048 1 1 -0.377218290576112 -3.65667193560794 0.00407081583862489 62.6376783018233 19.2353128203051 3.25638989534404 0.00121644894741842 44.0569101110936 29.0834291048732 1.51484578906521 0.130536055512234 CEP152 other 1 1 1 3.25638989534404 1.51484578906521 0.31412552666822 39.5424825923341 32.1443317037386 1.23015413593853 0.219302708890929 4.61482299389324 48.6016214533484 0.0949520377282659 0.924396545758524 ATP8B4 other 1 1 1 1.23015413593853 0.0949520377282659 0.933274953654233 -6.89873668893446 34.8645742830019 -0.197872391411872 0.843236915172526 -21.9442158872942 59.175703999158 -0.370831513683495 0.710942721250642 OCA2 other 1 1 1 -0.197872391411872 -0.370831513683495 5.5197280994983e-10 89.505780021183 35.9201655522635 2.49179753614868 0.0130804178720597 -172.868411564549 54.3106108038846 -3.18295833918673 0.00156213240199848 DTWD1 other 3.97199634039897e-06 1 1 2.49179753614868 -3.18295833918673 0.739629920254575 3.06288730648759 15.2896712645618 0.200323947682689 0.841320639852436 16.3045045857088 23.1176937133194 0.705282490022563 0.481011069526567 TGM5 other 1 1 1 0.200323947682689 0.705282490022563 0.257595428112562 2.11280215993204 46.8749444028522 0.0450731662052591 0.964069578799053 -101.626772808611 77.0277699959107 -1.31935239477927 0.187742164875068 FAM189A1 other 1 1 1 0.0450731662052591 -1.31935239477927 5.42209483056414e-05 -368.799074314122 326.915145444062 -1.12811865541796 0.259888780428515 -2251.90263226119 537.206922637175 -4.19187195356026 3.35010657522335e-05 TJP1 other 0.277773918169801 0.2759817796669 1 -1.12811865541796 -4.19187195356026 0.237204345686753 90.9420537041898 67.1548886853848 1.35421345317459 0.176368118344709 6.00441703839795 102.510138962464 0.0585738844876269 0.953318286548427 BMF other 1 1 1 1.35421345317459 0.0585738844876269 0.00486070080316305 30.6137315861169 151.007798154125 0.202729474638596 0.839441053221863 -564.537345442861 232.655916901966 -2.42649038528747 0.0156501754320417 DMXL2 other 1 1 1 0.202729474638596 -2.42649038528747 0.0222533995259115 -1327.8914722288 2744.06165868486 -0.483914589902188 0.628689446308343 -10268.6695698426 4227.74313009487 -2.42887735935182 0.0155489227299413 SCG3 other 1 1 1 -0.483914589902188 -2.42887735935182 0.000135760110711202 -2.2480124560595 32.2731416944356 -0.069655829523628 0.944499461756666 -170.484665833116 50.2360945665049 -3.39366878146589 0.000752504522999781 DNAJC17 essential 0.6616947796064 1 1 -0.069655829523628 -3.39366878146589 4.10503818001669e-20 -13.1938238416879 85.2103305042483 -0.15483831319056 0.877020602539154 -998.876702735674 128.84545193941 -7.75251813471385 6.43932752957259e-14 EIF3J other 3.51103915536827e-16 6.22425399008486e-10 1 -0.15483831319056 -7.75251813471385 1.31976784544001e-06 133.32866469379 108.308985653358 1.23100280082491 0.218986975253757 -518.38203402083 163.772633236181 -3.16525431494563 0.0016583265438983 SPG11 other 0.00791596753694918 1 1 1.23100280082491 -3.16525431494563 0.223919385919713 -2.61105475477155 4.17399134619449 -0.625553466264873 0.531934412661119 -10.7659268914108 6.49719900134025 -1.65701048854899 0.0982350736889998 RHOV other 1 1 1 -0.625553466264873 -1.65701048854899 5.14340479647214e-16 180.462478473193 56.9662232268342 3.16788560397639 0.00164322498227185 -394.096605251359 88.6731327310871 -4.44437444706626 1.1187856645327e-05 VPS18 essential 4.20267605919738e-12 0.0945373886530134 1 3.16788560397639 -4.44437444706626 0.00392188483270346 37.3950888730238 11.290461495341 3.3120956914343 0.00100309040597324 29.2837394650839 17.3950796154507 1.68344957956234 0.0930038957955478 OIP5 essential 1 1 1 3.3120956914343 1.68344957956234 1.20020356989517e-05 -38.5372828266894 20.7546973735271 -1.85679810854984 0.0640141234428445 -144.655801428668 31.380709806751 -4.6097045707216 5.3043985257947e-06 SLC30A4 other 0.0661912268797184 0.0454905217572154 1 -1.85679810854984 -4.6097045707216 1.44073215824575e-09 162.693382833453 117.241935774044 1.38767226725943 0.165945643133592 -712.876670347251 177.267588994085 -4.02147213933755 6.81555447325854e-05 BLOC1S6 other 1.01874170909557e-05 0.548992912820975 1 1.38767226725943 -4.02147213933755 0.000310948218936602 213.757847000478 160.282645745129 1.33363063734537 0.183024421369638 -507.298514391828 242.378434408918 -2.09300186144433 0.0369290341711739 MYEF2 other 1 1 1 1.33363063734537 -2.09300186144433 0.0659401041059233 -35.5786939972033 44.6939521819628 -0.796051641446957 0.426433246453279 236.009524214837 131.119934960523 1.79995150459687 0.0725562901719336 GSDMD other 1 1 1 -0.796051641446957 1.79995150459687 1.28845375568117e-11 207.341143131086 28.7854045968193 7.20299561653535 2.58876923545785e-12 117.171191784817 84.4485706518143 1.38748579023225 0.165999187979035 TSTA3 other 9.69046069647808e-08 1 2.48780723527499e-08 7.20299561653535 1.38748579023225 1.91364369673031e-26 181.097530263069 15.9071623797682 11.3846533994902 1.75469803558199e-26 68.9989723511126 46.6673004917974 1.47852932618719 0.139984916110945 PYCR3 other 1.70620472000474e-22 1 1.72346441054863e-22 11.3846533994902 1.47852932618719 7.90159566603242e-19 4143.27786824812 440.183789578236 9.41260892914303 2.76860901059729e-19 1933.907875846 1291.3798633245 1.49755151893679 0.134970093022983 EEF1D other 6.68000897606381e-15 1 2.70548472515568e-15 9.41260892914303 1.49755151893679 0.197056531534808 147.325718981101 89.1645879609347 1.65228957313915 0.0991921650711202 2.48685291700958 234.849351926694 0.010589141066848 0.991556067052329 TUSC3 other 1 1 1 1.65228957313915 0.010589141066848 1.02773365220414e-07 63.2401787744735 15.0005833818981 4.2158479550061 3.02836953750429e-05 34.5932149350508 18.4838837719161 1.87153389200655 0.0619420398343774 KCNN4 other 0.000662168792115125 1 0.257774815032365 4.2158479550061 1.87153389200655 1.49533518172575e-49 2902.4380877812 330.735121585881 8.77571778244764 3.8259839781343e-17 398.74721529681 403.379717677422 0.988515777621927 0.323445866189842 NUCB1 other 1.42640022984819e-45 1 3.72497800111155e-13 8.77571778244764 0.988515777621927 2.72377777473187e-32 468.268309338857 86.3117908613591 5.42531101099532 9.59083559446017e-08 -74.2826118311247 105.269817317684 -0.705640170410424 0.480787053803063 GYS1 other 2.48708148610767e-28 1 0.00087765736524905 5.42531101099532 -0.705640170410424 5.7666463289067e-20 -3.01029332997253 9.19731103444959 -0.327301460035127 0.743596258361276 -74.7828331075334 12.6757317819436 -5.89968566659485 7.29501431685525e-09 MAP4K1 other 4.92413930025343e-16 6.75153575024953e-05 1 -0.327301460035127 -5.89968566659485 2.04952016836945e-48 711.801863056938 122.828605056812 5.79508220196514 1.3068852737445e-08 -800.098254797191 173.736797832422 -4.60523196455437 5.40772382123096e-06 ECH1 other 1.95011844020353e-44 0.0463496008717706 0.000121344297667177 5.79508220196514 -4.60523196455437 6.69097947748431e-21 533.834703611354 142.871775744918 3.7364601988601 0.000211324862733245 -509.49857301177 202.087166967931 -2.5211822237709 0.012050067611349 HNRNPL essential 5.77030070138247e-17 1 1 3.7364601988601 -2.5211822237709 3.9136348177387e-70 291.178668093703 32.110186221146 9.06810898225027 4.09598058003641e-18 -191.208471886686 45.4187436980525 -4.2099022632122 3.10190584460005e-05 NFKBIB other 3.8208816725583e-66 0.256031308413288 3.9935810655355e-14 9.06810898225027 -4.2099022632122 2.01071856393039e-35 157.810900789659 18.2829238811492 8.63160082137473 1.13011545434297e-16 15.8926872231334 25.8605611344002 0.614553069461152 0.539169017295697 SARS2 other 1.85468680336939e-31 1 1.09971534862115e-12 8.63160082137473 0.614553069461152 1.57225148786056e-18 2358.39212494591 676.350807997595 3.4869362127742 0.000537927334552176 -811.023761152194 824.9084544537 -0.983168200996678 0.326067425319294 SNRNP70 essential 1.3247791036713e-14 1 1 3.4869362127742 -0.983168200996678 3.99651946758158e-35 1067.43212917132 201.501650882348 5.29738652014603 1.86602650385831e-07 -418.948618872746 251.277765962195 -1.66727293705635 0.0961765783419208 CLPTM1 other 3.68279268937643e-31 1 0.00170013674766531 5.29738652014603 -1.66727293705635 1.27193787755961e-16 75.896385974889 26.4225394228847 2.87241073843019 0.00427185045197535 -54.7093635424919 32.9346271271468 -1.6611502334999 0.0974004923269878 RELB other 1.04782242353361e-12 1 1 2.87241073843019 -1.6611502334999 3.91706179009647e-17 252.417318961537 72.6638277092692 3.47376854370332 0.000564516877121242 -100.342392004687 90.6696261632888 -1.10668143512557 0.269041899938556 CLASRP essential 3.24763593016899e-13 1 1 3.47376854370332 -1.10668143512557 7.3860357543089e-07 18.2973028660909 16.7549994202834 1.09205034313164 0.275411287222627 -30.0894566583562 20.4351654684617 -1.47243518555278 0.14162158127436 LIN7B other 0.00451803807091075 1 1 1.09205034313164 -1.47243518555278 5.50884980713675e-16 217.154977760898 62.3720013283769 3.4816099072662 0.000548918747561508 -59.2032835721632 77.5022595511835 -0.763891064789724 0.445347243713663 PPP1R37 other 4.49797586752716e-12 1 1 3.4816099072662 -0.763891064789724 1.25522168581192e-38 914.565004302117 244.615358437447 3.73878815354919 0.000209438127788017 -959.214488431411 298.478096089751 -3.21368469243713 0.00140725363711807 FCGRT other 1.16760721214224e-34 1 1 3.73878815354919 -3.21368469243713 6.49492061396701e-40 342.487242955402 81.4394565816899 4.20542151594371 3.16156051333281e-05 -286.532353594194 99.3719041288355 -2.883434267524 0.00412743121679292 PIH1D1 other 6.0636578851996e-36 1 0.268953952869222 4.20542151594371 -2.883434267524 1.87604222961567e-15 26.8927215270808 58.5029643325821 0.459681348353547 0.645974083389453 -256.212210701572 71.7750282541389 -3.56965670280732 0.000397175499078655 PPP1R13L other 1.52015701865757e-11 1 1 0.459681348353547 -3.56965670280732 4.23615686697482e-52 443.103110468832 45.7226079097907 9.69111629290834 3.04650690478953e-20 81.6407174028369 56.744393591357 1.43874508538711 0.150940216521357 ERCC2 ts 4.05781466287518e-48 1 2.97917910219368e-16 9.69111629290834 1.43874508538711 0.0538516137454612 -1189.41495686404 1197.69901766384 -0.993083353432185 0.321217634234988 203.93357903372 1461.42468226207 0.139544364830393 0.88908414233611 SLC17A7 other 1 1 1 -0.993083353432185 0.139544364830393 4.3411103343358e-35 40.4134558360479 5.30641762075234 7.61595839686627 1.64046791656295e-13 7.8843782596895 6.58557032936886 1.1972202657268 0.231871226785001 KLC3 other 3.99859672895671e-31 1 1.58387177344153e-09 7.61595839686627 1.1972202657268 2.08513586159551e-20 -104.022300313957 93.2757918250501 -1.1152121925597 0.26537100642947 -636.16989133706 113.814524701336 -5.58953167889998 4.00991987960247e-08 CD37 other 1.78716994697351e-16 0.000366987867381218 1 -1.1152121925597 -5.58953167889998 6.21790545643055e-49 1224.40926934185 179.684172303584 6.81422995495207 3.15437883939828e-11 -266.285843367906 220.317965136036 -1.20864334964009 0.22745347059709 DMPK other 5.92379852834138e-45 1 3.00990828855384e-07 6.81422995495207 -1.20864334964009 9.88837761675684e-18 29.5568695250316 16.209997872463 1.82337281951417 0.0689283624458795 -50.7732492922071 19.7974869448652 -2.56463102784751 0.0106608215528628 IL4I1 other 8.24987344566023e-14 1 1 1.82337281951417 -2.56463102784751 2.33510898629852e-39 1415.60459329985 298.528081399987 4.74194784846097 2.86787510030251e-06 -823.214894330647 364.596333737451 -2.25788034095661 0.0244446302595576 PTOV1 other 2.17655508612885e-35 1 0.0254093733886802 4.74194784846097 -2.25788034095661 2.63494390845071e-05 -163.806030215916 104.8887533837 -1.56171205140256 0.119079697161436 -439.635299525196 128.72490457875 -3.41530880107386 0.000696619602655566 NOVA2 other 0.140416160881338 1 1 -1.56171205140256 -3.41530880107386 5.51659852642067e-10 -9.59130604760875 44.1486685723518 -0.217250176681779 0.82811454496577 -199.600779697043 57.2141379880451 -3.48866183632356 0.000534560925722677 LILRB1 other 3.97029595946496e-06 1 1 -0.217250176681779 -3.48866183632356 5.5030497184132e-11 -18.9851138928115 16.392978651645 -1.1581247249966 0.247444235807825 -90.4148822127158 20.9032611143145 -4.32539600965898 1.8873969237369e-05 LILRA1 other 4.07775984134418e-07 0.157484399316607 1 -1.1581247249966 -4.32539600965898 8.86639079972856e-21 81.8384115065559 12.444269323594 6.57639346903179 1.37878606197352e-10 34.4655926205082 15.186426194184 2.26949989285218 0.0237244734646495 CCDC61 other 7.63484911764626e-17 1 1.31026039469343e-06 6.57639346903179 2.26949989285218 8.71792350280359e-20 -26.0072610341155 25.8063200852729 -1.00778650145308 0.314118502486704 114.0109140934 31.9333902351742 3.57027278512442 0.000396458218079277 TNNT1 other 7.42505544733782e-16 1 1 -1.00778650145308 3.57027278512442 3.81494401169986e-98 289.823732324337 28.6339913820767 10.1216672330827 8.86450859809498e-22 -105.825715264216 34.9710761855832 -3.02609261158061 0.00262335386264035 VRK3 other 3.75695686272202e-94 1 8.68101327011442e-18 10.1216672330827 -3.02609261158061 2.6070701075859e-30 356.046572241135 106.420149797108 3.3456687753207 0.000892203534309018 -339.321303501234 131.686972847248 -2.57672643060019 0.0103034368105845 PPP6R1 other 2.36200551747283e-26 1 1 3.3456687753207 -2.57672643060019 1.69325427844293e-45 162.19062838945 32.8120283743024 4.94302353207991 1.09821047485415e-06 -108.989675305194 41.154808878412 -2.64828529825502 0.00838292988782511 ZNF419 other 1.6021571982627e-41 1 0.0098355730127938 4.94302353207991 -2.64828529825502 1.4069718084007e-06 9.94612013071227 9.67859625017211 1.0276407728585 0.30468730056203 -17.2602054048447 12.0789896717965 -1.42894446256096 0.153734590174158 AURKC other 0.00842354021689497 1 1 1.0276407728585 -1.42894446256096 1.25627619914426e-71 196.598329516317 23.2548245350678 8.45408784830222 4.31468114236472e-16 -93.4370655208538 29.6553087397403 -3.15077028335373 0.0017411038336282 POP4 essential 1.22775872942369e-67 1 4.19214419792156e-12 8.45408784830222 -3.15077028335373 2.43271297246581e-17 44.8451030594668 8.90999961525748 5.03312065049633 7.08327543011795e-07 4.80076906305898 11.3623213567136 0.422516571424234 0.672857255315797 CCNE1 og 2.02109793752459e-13 1 0.00637707286973519 5.03312065049633 0.422516571424234 1.22971065343616e-68 247.567675040948 62.3187861346076 3.97260104691715 8.3224098864121e-05 -582.918697532094 79.470943344284 -7.33499154535984 1.09740727423501e-12 URI1 essential 1.19945977136163e-64 1.05460839053984e-08 0.694754777317682 3.97260104691715 -7.33499154535984 9.25682439158699e-53 278.09375855099 38.1586432537735 7.28783140169665 1.48517701151472e-12 -113.194448367477 49.3380117104944 -2.29426449188264 0.0222487762969135 PDCD5 other 8.8800716388494e-49 1 1.42859176737601e-08 7.28783140169665 -2.29426449188264 1.28267628658396e-44 60.5440591044325 30.8342967928308 1.96352975101769 0.0502183027699731 -264.208027116009 39.8678455660004 -6.62709567986608 1.01022079086287e-10 ANKRD27 other 1.21135948504989e-40 9.55062735681755e-07 1 1.96352975101769 -6.62709567986608 2.88698776957516e-28 2429.52105527806 560.895388548905 4.33150477767964 1.83787345906398e-05 -2473.47952701324 793.689759750589 -3.11643119572377 0.001950981612018 RPS16 essential 2.5965567999559e-24 1 0.157891708868187 4.33150477767964 -3.11643119572377 7.07351842843183e-26 505.466270919242 96.6368423564722 5.23057519879103 2.62405211952695e-07 -242.321181096752 137.26485371283 -1.76535489269313 0.0782008782478713 TIMM50 other 6.28977258656158e-22 1 0.00238421375580219 5.23057519879103 -1.76535489269313 8.70533958879694e-35 816.285224660001 122.307544271257 6.67403821672377 7.54398503889791e-11 -216.067989698821 168.02698650579 -1.28591242509354 0.199153013935079 FBL essential 8.01152402356983e-31 1 7.18413695254248e-07 6.67403821672377 -1.28591242509354 3.080149122541e-39 131.322383171564 26.5029222860369 4.95501521508636 1.03516868665237e-06 -138.151471472615 36.4099057981534 -3.79433751458983 0.000168857570092186 DYRK1B other 2.86977493747145e-35 1 0.00927718176977853 4.95501521508636 -3.79433751458983 1.49789346369024e-08 1367.42206009529 461.156888098983 2.96519925297479 0.00319090030949779 -236.654777666686 608.835319385892 -0.388700803207984 0.697687232157394 GPI other 0.000101422366426466 1 1 2.96519925297479 -0.388700803207984 3.05164831107198e-51 935.15177588635 130.513000897261 7.1652001674722 3.34646577618643e-12 -573.942170101115 178.850378893086 -3.20906320497206 0.00143022466334245 AKT2 og 2.91981710403367e-47 1 3.21461502460468e-08 7.1652001674722 -3.20906320497206 3.49660725338132e-05 513.333591614024 441.865919177239 1.16174063066429 0.245979337396595 -944.670794174125 603.197360951169 -1.56610564854676 0.118052697827608 PLD3 other 0.183501948657452 1 1 1.16174063066429 -1.56610564854676 0.89925634019064 9.14579118006002 29.0351812956196 0.314989980153484 0.752920649320937 17.8559801100975 39.6471292208663 0.450372585884475 0.652666700977706 PRX other 1 1 1 0.314989980153484 0.450372585884475 2.74941234128384e-07 121.036896181778 27.3359537615152 4.42775464275841 1.20387900542415e-05 -135.392213633362 76.0037565238826 -1.78138844480427 0.075541847504071 PIAS4 other 0.00172828059773102 1 0.104304077029948 4.42775464275841 -1.78138844480427 4.35439843679352e-29 249.57388101277 85.0401970037532 2.93477543333719 0.00351505094263881 -509.911573808935 116.153877728151 -4.38996599840036 1.42561513142667e-05 NUMBL other 3.92636107045672e-25 0.119637621829326 1 2.93477543333719 -4.38996599840036 0.0113063082309687 -2.67637509282267 19.7213381982961 -0.13570960884662 0.89211319846504 147.100969081966 52.3413924831943 2.81041374910301 0.00516958875186976 EBI3 other 1 1 1 -0.13570960884662 2.81041374910301 0.00122752743374847 117.33818364275 60.3957046933947 1.94282332226158 0.0526779474951992 -404.662819869546 166.60617684854 -2.42885844645136 0.0155478727644945 CCDC94 essential 1 1 1 1.94282332226158 -2.42885844645136 0.000889303955023663 -764.763201818602 407.31005562593 -1.87759470029131 0.0611009146305908 -4141.10424239942 1123.59598260013 -3.68558121115423 0.000256786392736008 SHD other 1 1 1 -1.87759470029131 -3.68558121115423 3.20802271762272e-34 944.985236495236 158.597203822201 5.95839783880827 5.2562527536057e-09 -317.538149129274 208.525455934804 -1.52277882671818 0.128538985059254 TBCB essential 2.94656886613647e-30 1 4.91301944879525e-05 5.95839783880827 -1.52277882671818 0.000444725950510526 2.63229125067082 74.3426147651345 0.035407568848457 0.971770879993245 -774.978236753812 205.079796416342 -3.77891069864578 0.000179312841508692 FSD1 other 1 1 1 0.035407568848457 -3.77891069864578 5.70507085778141e-30 323.048108419676 54.3998889096602 5.93839647276026 5.88499994684796e-09 -65.6649674544151 71.5256093064967 -0.918062328879046 0.35909380880072 POLR2I essential 5.16194811212062e-26 1 5.49717845035068e-05 5.93839647276026 -0.918062328879046 2.05874904743964e-14 -632.844173310385 549.654525858556 -1.15134897201453 0.250221131208148 -3865.53163948595 722.951161248216 -5.3468779727968 1.44829590062834e-07 CLIP3 other 1.63999949119041e-10 0.00130882500539783 1 -1.15134897201453 -5.3468779727968 0.0310771972432828 -101.495329035815 47.2889120858321 -2.14628175102855 0.0324004964253989 -284.429473611636 131.476783214383 -2.16334372242628 0.0310561797342834 ZFR2 other 1 1 1 -2.14628175102855 -2.16334372242628 9.94814262444994e-23 9.9576937929867 68.6419403763677 0.145067195629787 0.88472470145299 -397.580467381472 83.327325002027 -4.7713096198852 2.49937046908873e-06 SLC1A5 other 8.69467665376925e-19 0.0217245281173193 1 0.145067195629787 -4.7713096198852 4.32161687585063e-56 339.882048488149 47.3085997700469 7.1843607745783 2.94333201674955e-12 -86.5061291201309 57.4372732025533 -1.50609742240141 0.132766294756993 PRKD2 other 4.16387785988208e-52 1 2.82824773489464e-08 7.1843607745783 -1.50609742240141 0.654073921986571 -545.026067272527 1105.3015018875 -0.493101715994954 0.622189545508052 3.5978020093872 1453.54317256529 0.00247519446088251 0.998026217258822 APLP1 other 1 1 1 -0.493101715994954 0.00247519446088251 1.04194181789654e-16 299.589843750004 37.4806734775455 7.99318197762605 1.1840960703916e-14 -123.188281249999 103.636477677534 -1.18865754617115 0.235219987761025 CACTIN other 8.59810388128223e-13 1 1.14762591142354e-10 7.99318197762605 -1.18865754617115 3.70994360811118e-38 145.923619331257 27.2892230701533 5.34729841725895 1.44209156753592e-07 -49.7699370744587 33.3176611019708 -1.49380044782059 0.135949448294324 CCDC9 other 3.44765059501772e-34 1 0.00131605276453328 5.34729841725895 -1.49380044782059 5.29248750034687e-42 921.969499661302 294.281402709834 3.13295196764567 0.00184754105311311 -2382.7506322116 400.589563508232 -5.94810960960702 5.57976329557821e-09 HNRNPUL1 other 4.96699951907554e-38 5.17355652766012e-05 1 3.13295196764567 -5.94810960960702 5.64524121991083e-18 525.760558872235 64.8827076824566 8.10324626779398 5.38578136787294e-15 -307.833813440208 179.409071728753 -1.71582078026477 0.0869019943703988 FZR1 other 4.72111523221143e-14 1 5.22366934869996e-11 8.10324626779398 -1.71582078026477 5.94338910430229e-43 80.5989343510398 95.8729763511324 0.840684595582473 0.400986508157033 -1061.32225808576 130.506764597027 -8.13231606317772 4.43854676925109e-15 TGFB1 other 5.59213480823803e-39 4.30938505826588e-11 1 0.840684595582473 -8.13231606317772 0.439196660492099 -196.344893697046 157.896917594841 -1.24350048555641 0.214348614510051 -184.799659660498 193.116536538983 -0.956933378013408 0.339128760179009 MYH14 other 1 1 1 -1.24350048555641 -0.956933378013408 7.42685019903708e-16 -313.813878113098 120.807483931324 -2.59763607270799 0.00970368025153422 -928.458646111488 151.083319677847 -6.14534184244316 1.7985353450758e-09 SIGLEC8 other 6.0491694871157e-12 1.67803347695572e-05 1 -2.59763607270799 -6.14534184244316 1.54663298628282e-22 4450.77578495327 1064.31209525959 4.18183332198975 3.49851912013775e-05 -2166.37177817074 1381.80053310186 -1.56778907394664 0.117657477989218 RPS19 essential 1.35036526032353e-18 1 0.29688433253489 4.18183332198975 -1.56778907394664 3.81050918216802e-10 409.997860427812 489.168792790665 0.838152119412219 0.402402418319695 -1400.90944951216 596.880632807919 -2.34705127375608 0.0193671385819377 NOP53 other 2.75576024054391e-06 1 1 0.838152119412219 -2.34705127375608 0.0211199257647358 9.61153374645255 7.73783295530449 1.24214800215655 0.214848148473892 -0.551228441399075 9.67702870680285 -0.0569625716839681 0.954601045660258 NKG7 other 1 1 1 1.24214800215655 -0.0569625716839681 3.39396653678868e-10 450.009265765577 147.900607401528 3.04264650207871 0.00248677202345921 -17.0238292067967 184.077399468158 -0.0924819084579771 0.926357642782815 ETFB other 2.457231772635e-06 1 1 3.04264650207871 -0.0924819084579771 4.87397473171056e-19 -41.4051992582479 18.9370274849835 -2.18646771733742 0.0293110872586788 -146.508638606066 23.4241654030917 -6.25459375328389 9.50277553682154e-10 CD33 other 4.12776920028567e-15 8.90220012289442e-06 1 -2.18646771733742 -6.25459375328389 8.18343420244083e-36 858.037886715091 198.095020364952 4.33144601582776 1.83922786900492e-05 -554.347135680535 241.856015377957 -2.29205436471877 0.0223771397514306 NAPA essential 7.5590381727946e-32 1 0.157989673947523 4.33144601582776 -2.29205436471877 5.13440633928669e-37 694.045968852244 135.832366233751 5.10957725390628 4.84306980274312e-07 -465.289378761814 176.41535201452 -2.63746535348872 0.00865207330026565 RABAC1 other 4.75754091398305e-33 1 0.00437619787375869 5.10957725390628 -2.63746535348872 0.00765301569460653 -2350.695363495 1062.13070719042 -2.21318840287853 0.0274029785592889 -989.382489376966 1379.46623319494 -0.717221245122823 0.47362253097961 ATP1A3 other 1 1 1 -2.21318840287853 -0.717221245122823 2.64625821946065e-15 -167.977151021297 117.27873960663 -1.43228987269744 0.152775771920321 -736.770730154071 143.186681813366 -5.14552555323828 4.03794146593936e-07 MEIS3 other 2.13817664132421e-11 0.00361032346469638 1 -1.43228987269744 -5.14552555323828 2.41182560420312e-63 2018.57233869019 335.857749707374 6.01020027213583 3.92358786460958e-09 -1522.82271236397 411.215584204574 -3.70322227770042 0.000240266637858141 MEGF8 other 2.34212384424165e-59 1 3.67404767642041e-05 6.01020027213583 -3.70322227770042 1.75492193404159e-67 1473.86774581671 150.247863606779 9.80957539385745 1.14688858500162e-20 14.7841293566615 183.331482362224 0.0806415197551901 0.935763879203875 KDELR1 other 1.71034691691693e-63 1 1.12177172499008e-16 9.80957539385745 0.0806415197551901 1.24713364396039e-18 551.199864010052 127.402638019531 4.32643995900268 1.87884427884349e-05 -12.1994684029416 155.386098425995 -0.0785106809844498 0.937457688461056 CYTH2 other 1.05220665540938e-14 1 0.161298781338714 4.32643995900268 -0.0785106809844498 1.57274275317703e-52 306.212144501513 39.6595405067889 7.72102098482698 7.908155399941e-14 -26.6970211477832 48.3923177100418 -0.551678911263291 0.581449704138025 GRWD1 essential 1.50826030029677e-48 1 7.64560464066296e-10 7.72102098482698 -0.551678911263291 0.12531675333251 -60.8920302260951 36.7206311825863 -1.65825118646031 0.097982709079968 -90.584886481355 44.8062793464992 -2.02170070361874 0.0438148378098348 GRIN2D other 1 1 1 -1.65825118646031 -2.02170070361874 1.8394701103886e-10 26.809473481937 20.2606706845282 1.32322734520381 0.186451687873793 -47.8240776325898 24.7830066746493 -1.92971249455012 0.0542894428215811 CLEC11A other 1.3424452865616e-06 1 1 1.32322734520381 -1.92971249455012 0.302236048765589 3.93522626285117 9.60873592770805 0.40954671795105 0.682338700043593 -3.81935426498066 11.7245181326784 -0.325757888022315 0.744763112055647 CCDC114 other 1 1 1 0.40954671795105 -0.325757888022315 3.09029147861165e-65 297.544707518186 59.793925539687 4.9761694826458 9.33677688014974e-07 -351.218691015269 72.9601655710508 -4.81384174866272 2.04189486449879e-06 CARD8 other 3.00654457954128e-61 0.0178196164824809 0.00838255828299844 4.9761694826458 -4.81384174866272 5.51981335644399e-27 503.314239727493 75.557839281062 6.66131065309123 8.16167529534486e-11 130.631453536891 92.1951923105999 1.41690092794428 0.157222759356077 LIG1 other 4.93581710333221e-23 1 7.77073104869784e-07 6.66131065309123 1.41690092794428 1.59367613385387e-35 59.1221807983603 19.3610791842859 3.05366143258924 0.00239880237293506 -86.7910054242878 24.2132028622535 -3.5844496045415 0.000375851190324566 ZNF175 other 1.47048496870697e-31 1 1 3.05366143258924 -3.5844496045415 4.4491673694149e-08 -9.04589391184784 75.1764643343864 -0.120328802264649 0.904277864806025 -260.778304867541 91.7298410394974 -2.84289498283611 0.00467962618307999 PLA2G4C other 0.000292710721233806 1 1 -0.120328802264649 -2.84289498283611 1.39160212191229e-08 -3.30326044972888 10.1066414909806 -0.326840568419964 0.743944961959049 -39.5839336994309 12.6394896869074 -3.13176676273835 0.00185430149073932 SIGLEC5 other 9.44341199929682e-05 1 1 -0.326840568419964 -3.13176676273835 0.0350772877700678 -9.93955195056004 4.88453958253724 -2.03490048194 0.0424639465664683 -6.44071069911155 6.10866505296219 -1.0543564990502 0.292302315568123 HAS1 other 1 1 1 -2.03490048194 -1.0543564990502 4.37656161716636e-12 -16.6215976758084 80.8779355278421 -0.205514613687023 0.837265562319638 -357.22466363093 98.6424382240339 -3.6214095075348 0.000327286556604865 DBP other 3.32574917288471e-08 1 1 -0.205514613687023 -3.6214095075348 0.187129732182322 18.4692330108231 26.6316570825974 0.693506714717048 0.488359211529743 -5.47583293841304 32.4811899738641 -0.168584739131145 0.866201106141706 RASIP1 other 1 1 1 0.693506714717048 -0.168584739131145 1.72520441369266e-20 166.016360002472 52.6165825958938 3.15520985613056 0.00171437732201096 -103.245770918755 64.173596474758 -1.60885125020796 0.108369370105294 BCAT2 other 1.4802253869483e-16 1 1 3.15520985613056 -1.60885125020796 3.22094206621793e-10 134.312225381236 22.2803225819602 6.02828908276154 3.55681685502164e-09 -111.611126145987 64.2062713779998 -1.73832125352524 0.0828667185721959 MIER2 other 2.335182998008e-06 1 3.33451580158279e-05 6.02828908276154 -1.73832125352524 1.45318634006756e-15 641.153462592461 263.57150819576 2.43255982781061 0.0153920099039393 -530.090808315987 321.463895500467 -1.64899018438983 0.0998666465184092 PLEKHA4 other 1.17926071496482e-11 1 1 2.43255982781061 -1.64899018438983 9.43366453721615e-24 1262.29458267689 439.838767791378 2.86990296243195 0.00430709674090082 -1285.08562046107 548.210494396816 -2.34414633356304 0.0195218810169858 PPP2R1A other 8.29219112821299e-20 1 1 2.86990296243195 -2.34414633356304 1.66737835077235e-12 117.764921202636 209.416503595518 0.562347853109492 0.574169372514947 -764.803883740481 258.722034302455 -2.95608329535009 0.00328559350554872 CACNG7 other 1.27787876803193e-08 1 1 0.562347853109492 -2.95608329535009 0.0107772855510141 -40.7229661912833 17.4927003129444 -2.32799770548569 0.0203667884618384 -64.2123921886188 21.7054617901618 -2.95835181068222 0.00326042342210428 LILRB5 other 1 1 1 -2.32799770548569 -2.95835181068222 5.69746525830156e-30 118.18920559786 24.3190895151312 4.85993546445575 1.63984489407317e-06 -31.9439425121767 30.1961064963867 -1.0578828272446 0.290693279368268 LENG1 other 5.15563631223708e-26 1 0.0146290563000268 4.85993546445575 -1.0578828272446 1.66667441875343e-80 843.474578986259 87.4942934398332 9.64033819607089 4.5832628467988e-20 -179.891777464287 108.651706766271 -1.65567373783888 0.0985074325295775 PRPF31 essential 1.63700761409962e-76 1 4.48059775903051e-16 9.64033819607089 -1.65567373783888 5.67425587160876e-16 200.061150986198 50.9522206519264 3.92644615733022 0.000100177752067858 -8.56769205064723 63.273220683477 -0.135407870155795 0.892351893372861 TFPT other 4.63246249358139e-12 1 0.832376941931832 3.92644615733022 -0.135407870155795 1.70474392895756e-73 595.5796939744 64.1221382363824 9.28820701173176 7.43811480245841e-19 -274.636370214309 85.3679283688866 -3.21709072085675 0.00139126222377647 TMEM147 other 1.66809193448497e-69 1 7.26480672756113e-15 9.28820701173176 -3.21709072085675 1.04204201700288e-19 14.0147374311739 3.25289806709822 4.30838505913464 2.03307262045157e-05 -4.97744758514883 4.33069103465689 -1.14934257496464 0.251043394817229 GAPDHS other 8.87402981679651e-16 1 0.174274985025109 4.30838505913464 -1.14934257496464 0.886505680450393 219.777122253791 783.446047410993 0.280526174048712 0.779206602033439 479.515203932454 1052.98378446117 0.455387073389576 0.649056967370411 MAG other 1 1 1 0.280526174048712 0.455387073389576 1.16672806654954e-06 3.7574504186096 48.9727349277008 0.0767253538965464 0.938877148733499 -187.216681540105 65.821374592413 -2.84431436899352 0.0046596931389257 HAMP other 0.0070260364167613 1 1 0.0767253538965464 -2.84431436899352 4.17331885375959e-65 627.977728370885 163.062465639582 3.85114824498549 0.000135149079103645 -1723.15215050844 219.162675898553 -7.86243434674098 2.97164631528333e-14 USF2 other 4.05980458093733e-61 2.87833662098343e-10 1 3.85114824498549 -7.86243434674098 0.00627862603974563 1.63673448269839 47.2872615202211 0.0346125876204205 0.972404468075202 113.354732615691 63.5560288508886 1.7835402032691 0.0751922832948806 LSR other 1 1 1 0.0346125876204205 1.7835402032691 0.291895642831868 19.2420855842415 12.731717950557 1.51135028744488 0.131423647028302 17.5286931295189 16.8116360609509 1.0426524263295 0.297687075023403 HPN other 1 1 1 1.51135028744488 1.0426524263295 0.650479822918362 -44.3242371245934 131.399342076219 -0.337324650369123 0.736034509269935 31.2989687613066 173.50666471033 0.180390585073837 0.856929759911347 SCN1B other 1 1 1 -0.337324650369123 0.180390585073837 9.21195190746828e-43 720.497080619018 137.724919456064 5.23142132494669 2.62040683728104e-07 -378.39395891164 168.626846523559 -2.2439722186157 0.0253364188749772 ERF other 8.66199837859243e-39 1 0.00238116369303728 5.23142132494669 -2.2439722186157 1.2708041805303e-36 342.757038543525 117.353379596819 2.92072575771662 0.00367383018614027 -559.968341868619 143.684457456566 -3.89720886852283 0.000112644270087899 GSK3A other 1.176637590753e-32 0.890903532125195 1 2.92072575771662 -3.89720886852283 1.52530887008211e-53 92.5353617382643 23.018720198989 4.02000462833414 6.85913787901368e-05 -173.184211568791 29.9183816562887 -5.78855546260433 1.36069053070307e-08 ZNF574 essential 1.46490663882686e-49 0.000125428453120209 0.574932937018927 4.02000462833414 -5.78855546260433 4.32830262869441e-50 400.486334387232 103.565669877572 3.86697961651441 0.00012702571676099 -743.323466543863 134.608579934105 -5.52211060325976 5.7713837823161e-08 GRIK5 other 4.13179768935169e-46 0.000526350200947228 1 3.86697961651441 -5.52211060325976 9.005830404893e-46 404.653108389895 51.2385685649924 7.89743194868182 2.33567384973369e-14 -67.1978706795484 68.3359819109616 -0.983345359215061 0.325982843922069 SIPA1L3 other 8.5258196443122e-42 1 2.26163298869713e-10 7.89743194868182 -0.983345359215061 8.74996539606298e-60 110.473575798024 22.3466823467406 4.94362313312863 1.09674725229469e-06 -122.349328452955 27.5358276854441 -4.44327767629194 1.125454235034e-05 ETHE1 other 8.46996650338897e-56 0.0950671192333221 0.00982356513880354 4.94362313312863 -4.44327767629194 1.13212962779778e-35 1155.40840322306 430.450932339206 2.68418143955273 0.00754834024443966 -2146.35523712987 530.406371559666 -4.04662415879071 6.14942707638269e-05 CADM4 other 1.04495564645735e-31 0.497019186509375 1 2.68418143955273 -4.04662415879071 3.39248199595439e-80 608.403653883293 55.3232822685493 10.9972443596168 5.47162617458296e-25 -17.7091189380483 68.1699566809366 -0.259778937823509 0.795157203843526 SMG9 other 3.33107807182761e-76 1 5.36930676511826e-21 10.9972443596168 -0.259778937823509 0.0458628277800258 -116.891766710079 71.11633453389 -1.64366973461456 0.100965302670366 -588.119227469399 268.438053326142 -2.19089365379526 0.028988120487924 ADAP1 other 1 1 1 -1.64366973461456 -2.19089365379526 4.69570340526304e-20 1988.25459349426 200.218981928414 9.93040007667772 4.28150904108416e-21 1446.48008885619 745.56655781214 1.9401085975488 0.0530079889216946 LFNG other 4.01388727081885e-16 1 4.18988474760495e-17 9.93040007667772 1.9401085975488 3.11698891209384e-34 883.215131332054 66.0827831633415 13.3652834982593 2.06495225999656e-34 133.525223309337 246.076134736087 0.542617525476579 0.587669153997923 BRAT1 essential 2.8632660146494e-30 1 2.03108704293262e-30 13.3652834982593 0.542617525476579 1.93810979417616e-36 716.451411502032 51.6391550812737 13.8741892731286 1.54597296338689e-36 98.8752171808872 192.291593591451 0.514194174244356 0.607375567360332 IQCE other 1.7933329925512e-32 1 1.5212373959727e-32 13.8741892731286 0.514194174244356 2.73008010366502e-28 1563.36942042557 134.614709524945 11.6136596508858 2.28686123484096e-27 -412.30455741852 501.272280204074 -0.822516172748801 0.411230736107545 EIF3B essential 2.45570705324669e-24 1 2.24706984935473e-23 11.6136596508858 -0.822516172748801 3.17299248605009e-17 234.247512291651 26.3287308503345 8.89703015398763 1.5230602836312e-17 9.13384913399281 98.0417592906582 0.093162844078657 0.92581679038162 NUDT1 other 2.63263186567576e-13 1 1.48406994037024e-13 8.89703015398763 0.093162844078657 0.000530869566370557 10.2964619279854 3.95183801373421 2.60548683731496 0.00948820208848982 -1.61203039752011 4.55010223969411 -0.35428443419515 0.723297010957125 SPATA6L other 1 1 1 2.60548683731496 -0.35428443419515 0.00164284706645831 450.055690924344 145.317635600916 3.09704798776334 0.00208078840670305 128.300901006533 167.317105842095 0.766812815466802 0.443607815771771 SLC1A1 other 1 1 1 3.09704798776334 0.766812815466802 0.0186203431367363 208.458969625777 79.3193691723565 2.62809666542869 0.00888801681947332 -4.85829357754168 172.977543821936 -0.0280862675593477 0.977606138899066 LHX2 other 1 1 1 2.62809666542869 -0.0280862675593477 0.0290731063434901 63.6557659662433 50.3007970907 1.26550213213246 0.206364155451201 -175.456099613285 104.803953662479 -1.67413626568271 0.0948176952163918 FKTN other 1 1 1 1.26550213213246 -1.67413626568271 6.20932034302151e-06 -48.602112707028 55.8124345828552 -0.870811550692646 0.384334077955024 -562.979271664336 116.287696142556 -4.84126257840886 1.79176803706249e-06 FSD1L other 0.0352441022669901 0.0156654279480374 1 -0.870811550692646 -4.84126257840886 0.115853241169357 -13.9078960289464 12.756945306564 -1.09022149854246 0.276221915123641 14.6213486625925 14.9258330073531 0.979600177450026 0.327830516442065 CNTNAP3 other 1 1 1 -1.09022149854246 0.979600177450026 6.34944303989548e-08 306.575607864295 145.438551896976 2.10793908400204 0.0356038198016955 -1291.59592059264 312.514060938685 -4.13292098510104 4.29279364681871e-05 SPIN1 other 0.00041366621404919 0.350978808563898 1 2.10793908400204 -4.13292098510104 0.0166220243202335 27.2755815174798 18.7797324127072 1.45239457719983 0.147111172589664 -63.6524926409797 39.175686959751 -1.62479582569608 0.104928701387965 NMRK1 other 1 1 1 1.45239457719983 -1.62479582569608 0.0433233619962501 75.4184720434708 161.458425282893 0.467107689867093 0.640655111345736 -698.618493493491 333.983816260729 -2.09177349164759 0.0370341088569279 TMEM245 other 1 1 1 0.467107689867093 -2.09177349164759 0.0658245102459982 -257.658352925967 687.859164371497 -0.374580097600927 0.708154895207131 -3226.68837072768 1434.91689357511 -2.24869355512872 0.0250305980644885 PRUNE2 other 1 1 1 -0.374580097600927 -2.24869355512872 0.13554221320445 -113.262516791096 226.902909680046 -0.499167317646156 0.617912135187187 -920.991251877095 465.185823044488 -1.97983516748105 0.0483475657171606 MEGF9 other 1 1 1 -0.499167317646156 -1.97983516748105 0.530940673213246 100.255883169972 91.1254453112945 1.10019635928787 0.271852254599042 40.0514504543862 194.162364384548 0.206278135216063 0.83666972527713 TRIM14 other 1 1 1 1.10019635928787 0.206278135216063 0.106824439924927 4.78134052938599 10.9564310617187 0.436395802835086 0.662765103591152 48.5937512401285 23.3450333536633 2.08154559061717 0.0379655058600085 CORO2A other 1 1 1 0.436395802835086 2.08154559061717 0.030605044344265 354.587023914971 138.559927119994 2.55908783502676 0.0108304944256115 92.6601912155482 304.119684096369 0.304683307464525 0.760752411193198 TGFBR1 ts 1 1 1 2.55908783502676 0.304683307464525 1.63228698587488e-13 419.265721877768 54.9104515036858 7.63544480871052 1.43016990784865e-13 97.3102381076432 120.520770413138 0.807414670301804 0.419866866590871 SEC61B essential 1.27987622562449e-09 1 1.38125809700023e-09 7.63544480871052 0.807414670301804 0.00136898558231472 61.3296128411321 21.7491869334241 2.8198577275034 0.00502304548469656 -45.1067993417986 44.2584978252909 -1.01916697489048 0.308687592810176 C5 other 1 1 1 2.8198577275034 -1.01916697489048 0.709074648028283 -24.1485037629907 30.8634654815359 -0.782430079909127 0.434385621657859 -35.7200842193281 63.843813056596 -0.559491711243235 0.576112822320899 OGN other 1 1 1 -0.782430079909127 -0.559491711243235 0.798382203889459 1.32944092701022 9.61099388989052 0.138325020517245 0.890047268213281 13.0946302711745 19.8811924591341 0.658644107896979 0.510471196572014 ASPN other 1 1 1 0.138325020517245 0.658644107896979 0.519145320719326 -107.687373073704 202.072675109056 -0.532914076658741 0.594363949767927 -477.38406403058 418.005233444279 -1.14205284009732 0.25405742145035 ECM2 other 1 1 1 -0.532914076658741 -1.14205284009732 0.0498704738106867 44.1508447711864 76.8993345830351 0.574138190019223 0.566169012564194 -321.333951595679 165.239016894576 -1.94466148270958 0.0524554539643753 TLE4 other 1 1 1 0.574138190019223 -1.94466148270958 0.408055862604151 -25.623970831468 23.0095695456742 -1.1136223465895 0.266051984677494 -53.0894824534946 47.173152438182 -1.12541731280447 0.261028539037176 LHX6 other 1 1 1 -1.1136223465895 -1.12541731280447 0.124697155933744 55.4553750178753 32.6150347240428 1.70030096509434 0.0897842005704961 -25.7687062062064 67.4656261853565 -0.381953116916293 0.702681382005795 PTGR1 other 1 1 1 1.70030096509434 -0.381953116916293 0.0237466803756548 75.565654940656 33.1105324267032 2.28222409615236 0.0229548383666968 -35.2703953953948 68.4905848605882 -0.514967063972183 0.606835812297015 SUSD1 other 1 1 1 2.28222409615236 -0.514967063972183 0.155897731801291 -100.619879851882 82.2267699580767 -1.22368761296574 0.221727965985224 -317.547667842347 171.323141718064 -1.85350131136934 0.0644827548984094 AKNA other 1 1 1 -1.22368761296574 -1.85350131136934 0.345908468022851 -11.6700940251379 8.16579193801959 -1.42914418022365 0.153675590895852 -4.86960205700151 17.0137916173872 -0.286214981734291 0.774848792965364 TNFSF8 other 1 1 1 -1.42914418022365 -0.286214981734291 0.532552009335731 -565.356250875345 819.542361078122 -0.68984384178947 0.490658560955791 -1950.40394939548 1811.41330535963 -1.07673049746549 0.282194728588521 DNM1 other 1 1 1 -0.68984384178947 -1.07673049746549 0.286010908380042 103.285469806863 196.245745448566 0.526306797483836 0.598941457323538 686.89793007905 433.753971905766 1.58361185042538 0.114003814673321 ENG other 1 1 1 0.526306797483836 1.58361185042538 0.261129831138402 152.706829109282 260.286096154704 0.58668838391782 0.557715262180487 -698.863132589029 575.299748694624 -1.21478087583868 0.225104148896949 AK1 other 1 1 1 0.58668838391782 -1.21478087583868 1.03776500949266e-29 174.301970012859 25.0570095604308 6.95621596793063 1.2863803040439e-11 -81.4369478632698 28.8503615089273 -2.82273578575681 0.0049794945440965 CDC37L1 other 9.38243345082317e-26 1 1.23119458900041e-07 6.95621596793063 -2.82273578575681 1.72490726864277e-21 109.013905678259 16.4493400313628 6.62725103076535 1.00925562520699e-10 -23.3503938007547 18.9401293591878 -1.23285292079737 0.218293443637374 PLGRKT other 1.49428716682523e-17 1 9.60003950696888e-07 6.62725103076535 -1.23285292079737 9.17524802224333e-18 373.320518070457 48.2835746600828 7.73183263042638 7.39898852354305e-14 -208.652484468416 106.720661463665 -1.9551273540359 0.051206539876086 TBC1D13 other 7.65766199936428e-14 1 7.15482190226613e-10 7.73183263042638 -1.9551273540359 3.4753392732757e-08 91.5658111688517 25.7744346059455 3.55258272659568 0.00042308016630951 -31.6139593591157 29.6863499148504 -1.06493251780008 0.287495861854187 RIC1 other 0.000230136966676317 1 1 3.55258272659568 -1.06493251780008 5.82028679425611e-11 64.4758337256185 16.1686351982781 3.98771033763474 7.82188787444633e-05 -26.9890754424504 18.6416631380301 -1.44778259550196 0.148396530206889 KDM4C other 4.30817628510837e-07 1 0.653753388546225 3.98771033763474 -1.44778259550196 0.111100705795033 -198.287924634892 95.5059503042688 -2.07618398647596 0.0384663829494705 -128.168896967198 109.954691246733 -1.16565192002216 0.244396896479248 DOCK8 other 1 1 1 -2.07618398647596 -1.16565192002216 9.41639199355316e-08 976.074193667238 262.171990776775 3.72303002611104 0.000222835062614122 -225.864974629843 301.835018735091 -0.748306063280472 0.454681815831878 KANK1 other 0.000608863906303147 1 1 3.72303002611104 -0.748306063280472 0.02645191440153 196.755462624406 72.7287925254575 2.70533107717326 0.00710956909233025 144.17740453239 83.9939620579334 1.71652105698915 0.086825716691557 ELAVL2 other 1 1 1 2.70533107717326 1.71652105698915 0.264618643433233 -24.7058143598652 633.097875760644 -0.0390236886045181 0.96888932323422 -2094.74785624047 1373.7483067415 -1.52484108330526 0.128022094309845 NCS1 other 1 1 1 -0.0390236886045181 -1.52484108330526 9.30961033015208e-10 268.586496943868 50.6941465953487 5.29817572604154 1.86418420164811e-07 -33.6343990408365 59.2312683009416 -0.567848705686111 0.570431346140118 TESK1 other 6.63682120436541e-06 1 0.00169883106296192 5.29817572604154 -0.567848705686111 0.115596963707625 -87.3841189323424 63.4445219633932 -1.37733118996093 0.169113298900167 -260.766981740478 130.905194653781 -1.99202928829643 0.0469882388175846 KCNT1 other 1 1 1 -1.37733118996093 -1.99202928829643 0.791329102364907 -24.7075368050979 41.3313713665894 -0.597791362545266 0.55029022962813 -1.76696469989158 48.2659912137482 -0.036608896978133 0.970813643085697 CA9 other 1 1 1 -0.597791362545266 -0.036608896978133 0.00459154986142451 134.152845353622 106.798796558048 1.25612693847826 0.209741067421497 -543.746044461172 231.740891181123 -2.34635347128355 0.0194039975695625 FUBP3 other 1 1 1 1.25612693847826 -2.34635347128355 7.92742887835727e-11 348.335558087276 56.6397137284182 6.15002328150016 1.75657460130104e-09 24.4983399398438 66.6645753044923 0.367486627312136 0.713434788459825 CREB3 other 5.85044251222766e-07 1 1.6518827550635e-05 6.15002328150016 0.367486627312136 0.118613322707531 179.880054329241 103.177848888256 1.74339798966013 0.081970624668857 -4.32658870286773 121.439658221923 -0.0356274775984727 0.97159574104884 RGP1 essential 1 1 1 1.74339798966013 -0.0356274775984727 1.71299857994748e-14 425.146134003377 175.81716985778 2.41811499040328 0.0160091293315279 -779.497994878573 198.59539404179 -3.92505575791221 0.000100704369357934 MPDZ other 1.36577376779213e-10 0.801103258242365 1 2.41811499040328 -3.92505575791221 0.828926131453301 -1.18640434928015 7.9880077177416 -0.148523185154805 0.881998243132161 -9.86483200734301 16.376059113544 -0.602393526974032 0.54722394548089 LHX3 other 1 1 1 -0.148523185154805 -0.602393526974032 0.930062865613395 -24.5564744553622 65.8105936094573 -0.37313862569131 0.70922745128808 -22.3693582705019 76.595658369412 -0.292044728731452 0.770391975746776 DDX58 other 1 1 1 -0.37313862569131 -0.292044728731452 1.21018852543685e-05 1550.73177265076 330.327653470497 4.69452604515068 3.58448150251983e-06 601.818911901149 696.090807121648 0.864569544295067 0.387750505515511 EDF1 other 0.0667297952925881 1 0.0316473871857476 4.69452604515068 0.864569544295067 0.425778589867651 -10.5531910681273 26.5676577224858 -0.397219475588003 0.691399999718848 55.7368596890228 57.4126853339855 0.970810882033928 0.332180712154092 PIP5K1B other 1 1 1 -0.397219475588003 0.970810882033928 0.0213335052367052 76.558871378476 149.397704796227 0.512450117509497 0.608595520116556 -283.613719555763 172.014852034923 -1.64877460405677 0.0999141326204344 GLIS3 other 1 1 1 0.512450117509497 -1.64877460405677 2.4294587715751e-09 406.947475445438 97.3402647037852 4.18066949667554 3.51577634674303e-05 -154.339966296968 113.312638588869 -1.36207194730464 0.173880071842607 BAG1 other 1.70450827413709e-05 1 0.298278465257679 4.18066949667554 -1.36207194730464 0.000517629668058893 343.593337690454 171.476189878511 2.00373788299056 0.0457135378946148 -829.727533597484 361.334719985256 -2.29628509995203 0.0221309007544134 RAPGEF1 other 1 1 1 2.00373788299056 -2.29628509995203 0.00547154739215947 932.611498476062 349.887332986391 2.6654623090123 0.00797442167786969 -463.488946181785 732.547599243084 -0.632708299994009 0.527256591399156 NPDC1 other 1 1 1 2.6654623090123 -0.632708299994009 0.0865644448577599 166.981297521473 119.733975693685 1.39460246395443 0.163844264406977 -257.444761528591 258.737999257138 -0.995001747975715 0.320286034265404 APBA1 other 1 1 1 1.39460246395443 -0.995001747975715 0.000533578128916238 200.733916098199 104.330129745587 1.92402632477978 0.0549989304211702 -519.245118663455 219.844505784481 -2.36187443852922 0.0186194529812273 SETX other 1 1 1 1.92402632477978 -2.36187443852922 4.78262999191607e-09 550.519003685965 244.35762582522 2.25292336110571 0.0247580858627629 -727.105948492142 275.32526652816 -2.64089801005522 0.00856424399856832 SH3GL2 other 3.31149300640268e-05 1 1 2.25292336110571 -2.64089801005522 0.268034065501435 -1764.54551705732 1837.95583884607 -0.960058712925967 0.337557762542426 -6139.95917833242 3873.07617111315 -1.5852926477735 0.113624847917235 PTGDS other 1 1 1 -0.960058712925967 -1.5852926477735 0.227603347196455 170.153362206994 1140.28568476465 0.149219940652077 0.881449081583507 -3641.06313374935 2402.89413955462 -1.51528237295723 0.130425525023816 ABCA2 other 1 1 1 0.149219940652077 -1.51528237295723 0.0161798467180391 103.483687482532 35.8617928844769 2.88562503876727 0.00410160827954597 61.6719386174964 41.9588795808794 1.46981852789034 0.142337117337907 SHB other 1 1 1 2.88562503876727 1.46981852789034 1.29476233573079e-24 618.591129262862 89.1252987565785 6.94069066688209 1.42031960478156e-11 -298.955826836925 103.756665536082 -2.88131683195778 0.00415563935209758 UBE2R2 other 1.14379304738458e-20 1 1.35867773393404e-07 6.94069066688209 -2.88131683195778 0.00153247283315695 70.5871432803404 44.4888953305173 1.58662386997775 0.113321139179333 -222.551335538658 96.1378564462502 -2.31491884430651 0.0210799099783673 ABHD17B other 1 1 1 1.58662386997775 -2.31491884430651 4.59402642349759e-07 57.0932448679695 10.9753727409169 5.20194131130709 3.04942734657632e-07 14.1012156565879 12.940823490578 1.08966911316384 0.276464980458942 EXOSC3 essential 0.0028492151878532 1 0.00276705037428335 5.20194131130709 1.08966911316384 6.22667721342572e-05 -116.632249474731 382.701632796537 -0.304760260943905 0.760694168817682 -3447.86594024464 827.017897101028 -4.16903425225808 3.69126738312603e-05 ZFAND5 other 0.316688803074832 0.303274528197635 1 -0.304760260943905 -4.16903425225808 3.64920016627477e-12 53.10393799974 68.6247240164757 0.773830988187153 0.439448205695974 447.461658570626 86.8542953869938 5.15186562249899 3.907750317205e-07 PDLIM1 other 2.77923084663487e-08 0.00349587343377159 1 0.773830988187153 5.15186562249899 8.4742594555502e-13 113.696746074018 17.9977850053094 6.31726326547832 6.55137184331679e-10 53.3239856769551 22.7406689667328 2.34487322052674 0.0194791899445728 CCNJ other 6.53619631806587e-09 1 6.18711556882838e-06 6.31726326547832 2.34487322052674 3.05007570333127e-09 -157.209477219631 246.232646131426 -0.638459114538861 0.523508544640705 -1052.7512033792 281.441446180946 -3.74056919357343 0.000208005380829989 ATRNL1 other 2.13108789391756e-05 1 1 -0.638459114538861 -3.74056919357343 1.35961830853055e-13 -16.6493288004945 77.2001450766603 -0.215664475551977 0.82934968619227 399.251326692312 93.0984602518324 4.28848474628186 2.21487509832628e-05 HPS1 other 1.0681161431816e-09 0.18410041817288 1 -0.215664475551977 4.28848474628186 4.76600370735935e-16 267.994415420581 31.5644738465428 8.49038120272466 3.22748167198885e-16 421.134132893283 64.5528420516371 6.52386664178797 1.8951134347364e-10 PHYH other 3.89763783187848e-12 1.78898708239116e-06 3.13646668883876e-12 8.49038120272466 6.52386664178797 5.70672499554657e-10 1426.23227180673 1027.10004369465 1.38860112075971 0.16566141887815 -3960.76146983917 1329.05603636195 -2.98013128226033 0.0030420023014666 RASSF4 other 4.10313527179798e-06 1 1 1.38860112075971 -2.98013128226033 1.45798706693017e-10 -32.7996523584509 84.604630609941 -0.387681526672808 0.698440055907914 -427.532542181209 102.027798421092 -4.19035349970687 3.37029594433052e-05 DNMBP other 1.06768392911296e-06 0.277611276934505 1 -0.387681526672808 -4.19035349970687 3.13228603190959e-10 -19.6094865965952 120.069529825204 -0.16331775951103 0.87034375126232 -472.041407982569 136.125494693345 -3.46769287447554 0.00057695742110021 RAB11FIP2 other 2.27216028754722e-06 1 1 -0.16331775951103 -3.46769287447554 0.014515834937291 42.9308784018195 101.464128873294 0.423113851944964 0.672420338443763 -192.69048982984 131.293454596862 -1.46763211023351 0.142923518676691 CXCL12 other 1 1 1 0.423113851944964 -1.46763211023351 8.68806086598776e-07 130.978441106799 47.4553922921484 2.76003283884916 0.00602261740902889 -17.1020235875206 57.2358823946983 -0.298798985391456 0.765235460706796 ERLIN1 other 0.00528668503695355 1 1 2.76003283884916 -0.298798985391456 9.32676103583874e-25 -215.502353863165 417.73963702329 -0.515877199010326 0.606201081951452 -2815.78974471562 473.60071140111 -5.9454930639469 5.64511492753639e-09 EIF3A essential 8.24485675568145e-21 5.23245702633348e-05 1 -0.515877199010326 -5.9454930639469 0.37435200826111 -8.03862012615518 5.9807862681916 -1.34407413435053 0.179623369522501 -6.39232089984929 7.21439358919928 -0.886051034063247 0.376078459695099 PKD2L1 other 1 1 1 -1.34407413435053 -0.886051034063247 2.22174088851665e-19 15.544216380279 8.54830158691458 1.81839821890157 0.0696861485284441 155.611926998123 17.4057085731492 8.94028107756417 1.09447791407329e-17 CUBN other 1.88670236252834e-15 1.0708371911293e-13 1 1.81839821890157 8.94028107756417 1.62889839862571e-16 54.9728905289054 6.47346453009994 8.49203548938834 3.1882701600743e-16 34.1142763427633 13.0538212980536 2.61335555036669 0.0092744078660016 TRDMT1 other 1.34009471254938e-12 1 3.09867976857621e-12 8.49203548938834 2.61335555036669 5.21258501363955e-19 165.565548350719 37.9533096280189 4.36234810543349 1.60621711191712e-05 -73.7918324301179 46.0825521988653 -1.6012965625618 0.110032198396538 DDX50 other 4.41297447254724e-15 1 0.138407728533898 4.36234810543349 -1.6012965625618 9.70304008318415e-34 28.0086331254621 88.7155140401445 0.315712910289716 0.752370804495732 -946.628775605314 115.56728121461 -8.19114861625419 2.86562494520935e-15 MAPK8 other 8.90253927632146e-30 2.78452775925993e-11 1 0.315712910289716 -8.19114861625419 5.00414463176605e-07 29.751798851204 49.0563404818622 0.606482231633325 0.544509500292149 -131.100754640014 56.9939648853264 -2.30025678865811 0.0219039731764383 SEC23IP other 0.00309556386921048 1 1 0.606482231633325 -2.30025678865811 7.94396082557377e-32 142.245179742823 76.8209237877582 1.85164630584006 0.0647509757550266 -454.22358759943 89.2510323805471 -5.08928104789555 5.34919613914735e-07 ATE1 other 7.2369483120977e-28 0.0047591798049994 1 1.85164630584006 -5.08928104789555 5.11406059625903e-17 191.23498190477 33.5390844922673 5.70185456161931 2.18479397974398e-08 48.3233734448324 38.9659192891699 1.24014457573091 0.215587389290834 NSMCE4A other 4.23546498582173e-13 1 0.000202202682825305 5.70185456161931 1.24014457573091 0.0031431118788955 -74.3682889925071 111.785548985324 -0.665276412448184 0.50622467223378 -299.358912910469 129.873153826305 -2.30500995849255 0.0216337978568521 PLEKHA1 other 1 1 1 -0.665276412448184 -2.30500995849255 0.00973304698260285 254.601917113044 238.084863020219 1.06937465021211 0.285489854235365 741.378591044214 289.080405251121 2.56461032147851 0.0106614480787348 PALD1 other 1 1 1 1.06937465021211 2.56461032147851 0.15554412094796 -200.034677191993 196.1444009181 -1.01983373604183 0.308370284771547 37.3232913125777 238.156689954402 0.15671737510176 0.875539803543994 UNC5B other 1 1 1 -1.01983373604183 0.15671737510176 1.63925636664704e-15 -35.0155060614632 79.3849946788993 -0.441084693689227 0.659369325215443 457.119783765396 96.3885151769827 4.74247147521736 2.86083228418749e-06 CDH23 other 1.32910906207742e-11 0.0248005550716213 1 -0.441084693689227 4.74247147521736 0.429026864032074 316.121793064553 358.3150408771 0.882245390231835 0.37812803722186 60.8014329122229 435.062758338934 0.139753246507153 0.888919193905657 VSIR other 1 1 1 0.882245390231835 0.139753246507153 1.91387978911924e-17 -1371.0245277699 1233.54485002939 -1.11145089514762 0.266984030496402 -9449.35463160605 1497.75857489791 -6.30899718417578 6.88020520644174e-10 SPOCK2 other 1.59158243263156e-13 6.45844862728687e-06 1 -1.11145089514762 -6.30899718417578 4.39617689044182e-46 196.788835635756 122.195931195606 1.61043689188591 0.108022908129737 -1244.26698320213 148.369152334829 -8.38629164904951 6.94140797445646e-16 MICU1 other 4.16537760369363e-42 6.76093136712059e-12 1 1.61043689188591 -8.38629164904951 6.65475387673662e-14 -92.0215640089512 238.337127859616 -0.386098317267434 0.699611329709173 -1467.65113060888 288.935167604864 -5.07951712065726 5.61048314467547e-07 PPP3CB other 5.25326271029589e-10 0.00498771951561649 1 -0.386098317267434 -5.07951712065726 5.4984358885571e-33 -150.380596166508 217.964537762171 -0.689931480186897 0.490603498476113 -2186.10952456742 263.111689771742 -8.30867502110581 1.22990537015554e-15 CCSER2 other 5.03601743032945e-29 1.19682091569835e-11 1 -0.689931480186897 -8.30867502110581 1.1051220305294e-18 216.767654195741 91.0239519255526 2.38143532125515 0.0176726274982407 -368.546635043802 109.437943921368 -3.36763120575989 0.000825278241969698 BMPR1A ts 9.32944018172921e-15 1 1 2.38143532125515 -3.36763120575989 9.26265875482463e-21 83.925407509976 32.2230397355518 2.60451553294585 0.00951399184659516 -135.777215085749 38.7417063416404 -3.50467823715377 0.000504353021392325 MINPP1 other 7.97422292202853e-17 1 1 2.60451553294585 -3.50467823715377 0.221642525196908 -264.656944754884 520.979602997553 -0.507998668723557 0.611710589878324 329.249584472461 630.044667763692 0.522581336401297 0.601530453043223 ACTA2 other 1 1 1 -0.507998668723557 0.522581336401297 0.268327424653681 -441.036284152055 295.018233872274 -1.49494584915385 0.135650321923559 -311.302121483049 356.779160018594 -0.872534487347368 0.383396017878324 LIPA other 1 1 1 -1.49494584915385 -0.872534487347368 1.68333399086137e-08 3.99768906780032 42.1824310198431 0.0947714242908322 0.924539725029049 -169.306509125697 50.803865770043 -3.33255169777907 0.000933539091706665 TLX1 other 0.000113759711102411 1 1 0.0947714242908322 -3.33255169777907 1.32341765244952e-30 109.456520928847 46.3463774126795 2.36170607152786 0.0186278011326644 -280.180799383751 55.8188582325637 -5.01946489511494 7.55070102441542e-07 TWNK other 1.20033981077172e-26 0.00668614575711985 1 2.36170607152786 -5.01946489511494 1.65502848523249e-10 252.77315591338 149.747835561456 1.68799204987269 0.0921246031450765 -420.205610843987 180.353970913622 -2.32989386768333 0.0202653215806655 LZTS2 other 1.20966031985643e-06 1 1 1.68799204987269 -2.32989386768333 2.71120485093279e-06 36.7848223936785 104.816664839474 0.350944408029144 0.725798789954062 -324.722750257806 126.239565672809 -2.57227398183095 0.0104317956083671 SFXN3 other 0.0158876604264661 1 1 0.350944408029144 -2.57227398183095 0.847963955266674 -4.66402027656615 44.834266832184 -0.10402802601911 0.917194723994147 12.379676221005 53.9976956986923 0.229263046521165 0.818771488208682 KAZALD1 other 1 1 1 -0.10402802601911 0.229263046521165 1.67634721700211e-22 -8.94006485519524 160.245688355773 -0.0557897372898218 0.955534750220804 -1153.29784934213 192.997422022101 -5.97571634511295 4.7500910802193e-09 FBXW4 other 1.46311585099944e-18 4.40760951333549e-05 1 -0.0557897372898218 -5.97571634511295 9.64506079517094e-11 192.109881098813 41.6229549627806 4.61547915736877 5.15941538087292e-06 45.5094984283182 50.1300414830742 0.907828860338844 0.364467851288507 NPM3 other 7.10262276956388e-07 1 0.0452945076286833 4.61547915736877 0.907828860338844 1.92657214242913e-25 -165.287435864472 164.095126851129 -1.00726596234893 0.314363106706035 -1432.85681944324 198.150828882943 -7.23114219365541 2.15176208230838e-12 TNKS2 other 1.70848417590615e-21 2.06418536555843e-08 1 -1.00726596234893 -7.23114219365541 3.62609519187497e-35 99.6651944488133 150.314246805996 0.663045563322065 0.507650155812957 -1289.03458915565 180.809845858912 -7.12922785278791 4.19202245514325e-12 GBF1 essential 3.34253454787035e-31 4.01428070304517e-08 1 0.663045563322065 -7.12922785278791 9.75659466103181e-08 1178.57372494567 225.793959182093 5.21968669673399 2.78423646176243e-07 427.270876535695 439.437128141054 0.972314010750921 0.33143594396747 ARHGAP21 other 0.000629788185369603 1 0.00252836513092646 5.21968669673399 0.972314010750921 3.89289029331121e-16 -102.572795665967 74.9616678633746 -1.36833662576607 0.171908207959302 -544.536365703437 90.5189380489723 -6.01571756629351 3.78361757376155e-09 CPEB3 other 3.18710928313389e-12 3.51649417305398e-05 1 -1.36833662576607 -6.01571756629351 5.79129693685099e-11 50.4514284153994 59.7704349662371 0.844086686735645 0.399081740074451 -229.656934555706 71.8965990436935 -3.19426701138029 0.00150308862627799 FBXL15 other 4.28729712235078e-07 1 1 0.844086686735645 -3.19426701138029 1.19102410882069e-24 551.194391464326 187.219974647147 2.94410034240822 0.00341128108536162 -801.512604869921 225.202969625032 -3.55906765441174 0.000412867199330686 CUEDC2 other 1.05250800496485e-20 1 1 2.94410034240822 -3.55906765441174 3.26276568101663e-36 -2.47948128647066 57.9038269809731 -0.042820680700179 0.965864036313286 -538.622929495882 69.1641226225766 -7.7876059013299 5.00675473299333e-14 SUFU ts 3.01675314866797e-32 4.84303385322445e-10 1 -0.042820680700179 -7.7876059013299 5.87476857220059e-22 56.4012821064411 16.0532042286081 3.51339715755497 0.000488529499588642 -187.003746191423 31.2338964854469 -5.98720515957896 4.45732222646969e-09 ANKRD26 other 5.11104865781451e-18 4.13773222283181e-05 1 3.51339715755497 -5.98720515957896 3.39642579380484e-32 349.910962440308 88.059822116276 3.97355972373279 8.28137962795305e-05 -1347.08761386614 171.333481424544 -7.86237227345088 2.97293701322471e-14 ACBD5 other 3.09821960910878e-28 2.87928949730813e-10 0.6914123851378 3.97355972373279 -7.86237227345088 1.43849951859145e-05 -55.1196755948004 293.473578478819 -0.18781818751966 0.851106355431536 -895.381352582455 340.743351796098 -2.62772948573405 0.00889815892518396 LHPP other 0.0787434636476962 1 1 -0.18781818751966 -2.62772948573405 2.62727895745736e-51 365.774720939993 31.6449860495606 11.5586943336659 4.34665522815496e-27 -356.87114561477 67.7811703476526 -5.26504844611509 2.22070160860425e-07 LARP4B other 2.51404323439095e-47 0.00199818730742211 4.27015409613944e-23 11.5586943336659 -5.26504844611509 1.58929554677559e-53 461.338161980699 32.8765632588843 14.0324327195614 4.41392727660882e-37 -168.9734324925 70.419115723603 -2.39953925516085 0.0168412983613956 GTPBP4 essential 1.52604158401392e-49 1 4.3441872256384e-33 14.0324327195614 -2.39953925516085 1.71532104871513e-20 64.4412384830227 35.0237635313727 1.83992900778065 0.0664582276377191 -143.578657617871 40.6713063725469 -3.5302199615301 0.000459407538803246 EDRF1 other 1.47191699190245e-16 1 1 1.83992900778065 -3.5302199615301 2.68582113748176e-40 226.077582168906 84.9464061075438 2.66141432614215 0.00806868992417796 -528.963333266476 98.6439194335004 -5.36235113430453 1.33515741398736e-07 BCCIP other 2.50936268874921e-36 0.00120845097539996 1 2.66141432614215 -5.36235113430453 0.0117633908091036 -125.932660661704 123.362986137351 -1.02083019068209 0.307899689379586 -353.875043961181 147.721815614464 -2.39555032876629 0.0170152929184937 NEURL1 other 1 1 1 -1.02083019068209 -2.39555032876629 0.237543353817035 -382.539624112241 232.782479217777 -1.64333512297702 0.101032862597097 -318.074940029075 278.746904156486 -1.14108869116089 0.254457944472056 SH3PXD2A other 1 1 1 -1.64333512297702 -1.14108869116089 3.40710114042354e-37 390.260387148062 46.1779701689874 8.45122437647023 4.3569581221166e-16 -499.314023094105 98.3453519930568 -5.07714917863487 5.68675687630509e-07 PITRM1 other 3.15838275717262e-33 0.00505382083597233 4.23278481563628e-12 8.45122437647023 -5.07714917863487 0.656034555763098 13.5893608729533 17.5550380616278 0.774100336624004 0.439290041723633 7.96999220576696 20.9986256526734 0.379548277948957 0.704465131359273 STN1 other 1 1 1 0.774100336624004 0.379548277948957 0.227489665806661 0.551980026409953 13.8379012414854 0.0398889988284598 0.968199797004329 37.772762524205 26.5653291534013 1.42188196901633 0.155772188945327 MAP3K8 other 1 1 1 0.0398889988284598 1.42188196901633 0.968718548526152 -13.4485366357555 146.431251275979 -0.091841983992946 0.926865962768399 12.8372768092703 185.996390978263 0.0690189564526045 0.945006318350474 DKK1 other 1 1 1 -0.091841983992946 0.0690189564526045 3.01437355532862e-05 5.56894373656278 18.3813244772222 0.302967489827172 0.762058475933766 56.2793900131724 21.3387326556021 2.63742889146687 0.00865092342947146 EBF3 other 0.159550792283544 1 1 0.302967489827172 2.63742889146687 6.22031484580774e-27 136.107554692255 37.8813655218338 3.59299494137311 0.000363989363911844 -119.458403857635 43.9761744318933 -2.7164346467345 0.00686019950367485 GLRX3 essential 5.56096147215212e-23 1 1 3.59299494137311 -2.7164346467345 0.000778104680096722 21.9456632008522 77.0401718549202 0.284859998004413 0.775886042102821 -168.017424404685 92.0419714331445 -1.82544356437135 0.0686149325692935 SORCS1 other 1 1 1 0.284859998004413 -1.82544356437135 1.20835100805228e-19 374.036808603399 67.3625483675653 5.55259291205046 4.89381240305362e-08 -531.352447803127 142.678760184835 -3.72411736066937 0.000221659849745185 FAM208B other 1.0285483780541e-15 1 0.000450230741080933 5.55259291205046 -3.72411736066937 5.21314080792115e-25 253.701444076116 73.1711296903561 3.46723421040135 0.000577916239185126 -249.975924496308 87.2555448567896 -2.86487150938759 0.00437293025271761 XPNPEP1 other 4.6151935572526e-21 1 1 3.46723421040135 -2.86487150938759 8.73336342387922e-21 344.008576826577 151.786592911627 2.26639632807929 0.023915290944905 -613.33188720173 180.827906520694 -3.39179886004785 0.000757524681201353 SMC3 essential 7.52117258064478e-17 1 1 2.26639632807929 -3.39179886004785 7.60739674287556e-22 32.7663909088214 66.3620600447038 0.493751864947362 0.621729495121051 -405.183477100326 78.9120360916471 -5.13462200658152 4.26502949153716e-07 SHOC2 other 6.61006702988458e-18 0.00381080385068845 1 0.493751864947362 -5.13462200658152 1.12444961308449e-18 108.391915890464 52.360992723162 2.07008901575919 0.0390322603660693 -288.962026433362 67.5959919291209 -4.27483964931469 2.3513073324193e-05 TFAM essential 9.49147918404619e-15 0.19520553473745 1 2.07008901575919 -4.27483964931469 2.68425697154716e-22 14.2641732895059 86.1756310538391 0.165524442525919 0.868607934449395 -727.570434901485 111.249366336507 -6.53999621625468 1.72556730494722e-10 CCDC6 other 2.34040365349196e-18 1.62910809260067e-06 1 0.165524442525919 -6.53999621625468 2.43195877452445e-27 114.537582522327 26.0973542633328 4.38885801857908 1.43480536368301e-05 -310.857989388761 48.7355647660962 -6.37846285111721 4.6172965306636e-10 CUL2 essential 2.17952145372881e-23 4.34349084639525e-06 0.123895443154028 4.38885801857908 -6.37846285111721 1.74169093322383e-44 371.665310091844 65.3316226140061 5.68890370728622 2.36692593274779e-08 -1028.59660788659 119.06167393804 -8.63919155396618 1.12156603347024e-16 CCNY other 1.64415624096329e-40 1.09408766565022e-12 0.000218845971741861 5.68890370728622 -8.63919155396618 2.8690267734805e-18 289.521576204696 55.6983950436144 5.19802367694773 3.10752733955059e-07 72.4965454651923 68.9604588471168 1.05127701696294 0.293716374063588 UBE2S other 2.40912178169157e-14 1 0.00281852729697239 5.19802367694773 1.05127701696294 6.42114314225745e-17 -656.067690127487 826.44133137057 -0.793846659434935 0.427715551084798 -5967.035907239 1002.01989267012 -5.95500743137783 5.34959538600444e-09 ZMIZ1 other 5.31285383590382e-13 4.96067980144192e-05 1 -0.793846659434935 -5.95500743137783 2.45423868519932e-37 -11.2438680575105 41.2204642240566 -0.272773930841576 0.785155554969219 -437.690442627569 50.049500633384 -8.74515104223879 4.81893692364858e-17 DNAJC12 other 2.27606095665385e-33 4.70713758701993e-13 1 -0.272773930841576 -8.74515104223879 1.1419792271815e-06 41.4768068020845 560.623604380828 0.0739833401197812 0.941057493995997 -2096.73078058574 679.728835631198 -3.08465769094335 0.00216718329282362 PPIF other 0.00688499276067729 1 1 0.0739833401197812 -3.08465769094335 1.55093627919332e-14 -26.4956301099507 26.9995552111381 -0.981335799895716 0.326968908329621 -186.002347911565 32.7826064329548 -5.67381206530871 2.54223963237994e-08 PBLD other 1.23780224442419e-10 0.000233352175856155 1 -0.981335799895716 -5.67381206530871 3.78522954164462e-06 29.4833535705984 149.068616497982 0.197783774098403 0.843306419601097 -509.539839650719 180.488860527526 -2.82310962660773 0.00497379755523422 TSPAN14 other 0.0219203767670146 1 1 0.197783774098403 -2.82310962660773 0.000233337774541027 -176.310146686179 138.45830382137 -1.27338080721863 0.203561417712639 190.707466362111 166.24665298538 1.14713567423749 0.251954648003891 LGI1 other 1 1 1 -1.27338080721863 1.14713567423749 5.47018368285421e-06 -7.04338942953949 62.9954320908852 -0.111807939016559 0.911026911931043 -249.738127241863 79.7296301773024 -3.13231262563863 0.00185066250053055 TBC1D12 other 0.0312303609151636 1 1 -0.111807939016559 -3.13231262563863 0.403168025789697 151.152735252762 124.561918771322 1.21347468587295 0.225605352122004 -79.4382974809113 272.330900455458 -0.291697700657749 0.770656500997562 NUFIP2 other 1 1 1 1.21347468587295 -0.291697700657749 0.0449822322910318 -39.2609144613593 211.382404074341 -0.185734071070322 0.852739684817226 -1098.65056113219 447.631236637367 -2.45436527036255 0.014503294381572 GIT1 other 1 1 1 -0.185734071070322 -2.45436527036255 0.000584309617296216 3020.63432735121 869.946092765525 3.47220862588018 0.000567596456828166 -2119.82504385376 2041.11002987325 -1.03856480681024 0.299581473307333 RPL19 essential 1 1 1 3.47220862588018 -1.03856480681024 2.57908771118769e-05 148.112779310717 40.0825545322423 3.69519310930085 0.000247680728090327 -192.150354379702 94.0437451843939 -2.04320185253095 0.0416331426321622 FBXL20 other 0.13754274763764 1 1 3.69519310930085 -2.04320185253095 0.0313974385467736 -491.112063256013 381.476525529078 -1.28739786170297 0.198635500587386 -2191.97763610727 863.083036225043 -2.53970654514837 0.0114391887352146 RUNDC3A other 1 1 1 -1.28739786170297 -2.53970654514837 0.00305980950346883 398.076481750112 176.516336841977 2.25518209176572 0.0246148239253918 -796.442674240475 399.364694154118 -1.99427412061899 0.046741547687922 UBTF essential 1 1 1 2.25518209176572 -1.99427412061899 1.0856169848313e-07 586.607033025809 124.290589808197 4.71964155879422 3.18389548897497e-06 -542.33426928734 272.227683788738 -1.9922083666855 0.046968519114429 PSMD3 essential 0.000697291789357141 1 0.0281520039135167 4.71964155879422 -1.9922083666855 0.114415079687439 -43.187257654768 79.780385032099 -0.541326763933164 0.588557598879969 -364.755181173954 174.739129185706 -2.08742702835784 0.0374269456581089 RAPGEFL1 other 1 1 1 -0.541326763933164 -2.08742702835784 0.160335384987212 -45.9166240515251 76.8520178190187 -0.597468034732096 0.550503692118429 -99.8142509640237 56.0069507886866 -1.78217613275576 0.0754131480303507 ASPA other 1 1 1 -0.597468034732096 -1.78217613275576 0.201484668853629 7.1525662377509 5.9520950338476 1.20168885024124 0.230133438513193 -6.0802722416486 4.33767001974269 -1.40173692650076 0.161702048632366 P2RX1 other 1 1 1 1.20168885024124 -1.40173692650076 2.55197638099522e-05 1063.71529006014 289.007900400976 3.68057512816887 0.000261794519661685 -1370.27829051034 652.632407692943 -2.09961729506244 0.0363354023662605 KPNB1 essential 0.136173459689905 1 1 3.68057512816887 -2.09961729506244 0.0236909008618952 56.2788507418091 26.2808811467935 2.14143697950841 0.0327924887371357 -84.0918510227472 61.536095249866 -1.36654512577202 0.172472219222965 GOSR2 essential 1 1 1 2.14143697950841 -1.36654512577202 0.278857397623702 3.37336399009464 42.1857339734973 0.0799645679322284 0.936302042262704 -148.05897675017 95.2630606125967 -1.55421184032997 0.120857782050337 PNPO other 1 1 1 0.0799645679322284 -1.55421184032997 0.115759303996822 5.22461992790425 34.4033439739862 0.151863723824486 0.87936434483374 -54.0185973421764 25.9626666979379 -2.08062592223883 0.0380487739730195 TRIM16L other 1 1 1 0.151863723824486 -2.08062592223883 0.00429382532174857 836.059205871967 253.163321147443 3.30244998399687 0.00103716630968788 154.601151236461 571.688827851293 0.270428848185705 0.786958020079339 CDK5RAP3 other 1 1 1 3.30244998399687 0.270428848185705 1.03676778372847e-09 536.810709232403 127.561230632846 4.20825909697816 3.12500640231075e-05 -1203.11615268354 288.056461296336 -4.17666782154158 3.57271049017016e-05 CBX1 other 7.37660278122804e-06 0.293855437816496 0.265938044836645 4.20825909697816 -4.17666782154158 0.00278197447999392 43.1306474479956 18.3805498407469 2.34653738988708 0.0193945461558127 -36.4607470038918 13.6494989188519 -2.67121505490097 0.00783992565433023 PIGL other 1 1 1 2.34653738988708 -2.67121505490097 0.132771292053895 -83.738937915499 133.4583194809 -0.627453861559254 0.530688728728862 -182.092186053101 97.259561214251 -1.87222915443731 0.0618410001567763 CAMTA2 other 1 1 1 -0.627453861559254 -1.87222915443731 0.00246582298814526 166.288998037401 75.413595261917 2.20502679205079 0.027971180192771 140.988026584938 54.9586808322796 2.56534590077223 0.0106392113210105 ENO3 other 1 1 1 2.20502679205079 2.56534590077223 0.000496477913949401 1041.03587619035 392.434502469043 2.6527633774313 0.00827363478538452 783.453289773749 285.991968608106 2.7394240949728 0.00640597193925434 PFN1 essential 1 1 1 2.6527633774313 2.7394240949728 0.000264966695873011 286.812692631958 91.0703016040501 3.1493548124936 0.00174831654788082 -186.31576956035 66.3687180245596 -2.80728293548482 0.00521919197109065 RNF167 other 1 1 1 3.1493548124936 -2.80728293548482 2.10579034475758e-08 178.144446325655 80.959388327962 2.20041739450899 0.0282986289849229 -340.912183150665 59.000252779885 -5.77814783984945 1.43511611889147e-08 SLC25A11 other 0.000141530169071157 0.000132274652678226 1 2.20041739450899 -5.77814783984945 4.4796500920783e-08 2747.75976998348 597.659534982838 4.59753356074606 5.60178116738563e-06 1536.08671011962 443.586866942652 3.46287688972137 0.000586975784010835 RASD1 other 0.000294671383056911 1 0.0491220190568046 4.59753356074606 3.46287688972137 0.406454719761597 24.8314738158748 18.5490569902931 1.33869197926716 0.181365375178714 -2.58998158334824 13.517876973359 -0.191596771331221 0.848146859345028 CHRNE other 1 1 1 1.33869197926716 -0.191596771331221 4.47293858976028e-07 -61.1948894271394 100.714347133407 -0.6076084606504 0.543762074504436 -405.036222053586 74.750855773372 -5.4184827432821 9.94040916347014e-08 RAI1 other 0.00277635298266421 0.000901893323401646 1 -0.6076084606504 -5.4184827432821 0.0701112536936076 88.3016029052019 40.0066690553458 2.20717207881126 0.0278199013231567 -23.9960963954501 29.155402923559 -0.823041151527357 0.410932465111159 NUP88 essential 1 1 1 2.20717207881126 -0.823041151527357 0.0060348791543167 210.605878470832 82.2511705498984 2.5605213526179 0.0107858163507281 -125.729540412975 59.9416566022814 -2.09753195923834 0.0365190838371625 C1QBP essential 1 1 1 2.5605213526179 -2.09753195923834 1.83531575496324e-07 271.423054098583 55.031474009285 4.93214217836121 1.15868776299918e-06 -142.574026634621 113.24162513017 -1.25902490776456 0.208694989409281 BLMH other 0.00116524197282616 1 0.0103667794155536 4.93214217836121 -1.25902490776456 0.441826064630059 118.009716145535 121.797086401856 0.968904262259409 0.333130121122052 -130.605655710814 250.629303477112 -0.521110875300109 0.602554101493699 CPD other 1 1 1 0.968904262259409 -0.521110875300109 4.25160970225003e-05 139.118032929319 55.5059701184318 2.50636161538094 0.0125611928534585 -334.934488900472 115.202534778518 -2.90735346704306 0.00383099686510452 GOSR1 other 0.220913640128912 1 1 2.50636161538094 -2.90735346704306 0.0257680225851541 37.6285453762858 17.5576550686467 2.14314185061536 0.0326520033130321 20.8898328122875 13.1243714139764 1.59168253879508 0.112177477557403 MED31 other 1 1 1 2.14314185061536 1.59168253879508 1.80351474726564e-40 -23.6851982757405 62.67824430835 -0.377885477442851 0.705698728919771 -698.640116706172 46.5202082302686 -15.0179920358052 2.02909277371549e-41 DRG2 other 1.68538453131974e-36 1.99946801921924e-37 1 -0.377885477442851 -15.0179920358052 0.102179635369713 55.4748078565322 27.6349869440181 2.00741212467047 0.0453196037193165 -17.4126654931829 21.5873068451213 -0.806615925650688 0.420325549134777 AKAP10 other 1 1 1 2.00741212467047 -0.806615925650688 0.949452847821028 -0.852376885852488 13.8870883164216 -0.0613790930417391 0.951085299639023 -3.40827674081305 10.8480180316055 -0.314184280564717 0.753530671791977 ALDH3A1 other 1 1 1 -0.0613790930417391 -0.314184280564717 0.0225567581144656 19.3504484903525 106.369645272895 0.181917016275726 0.855732010229442 824.281746457949 298.932993781518 2.75741307786318 0.00606967800486602 SYNGR2 other 1 1 1 0.181917016275726 2.75741307786318 0.0465774924547035 15.7689154568744 18.0019870121181 0.875954162518812 0.381535079647724 -33.0659265584972 14.0624064067669 -2.35137042708321 0.0191466074080706 B9D1 other 1 1 1 0.875954162518812 -2.35137042708321 3.95186250114994e-06 178.271970984257 37.7568049787351 4.7215851840393 3.1592668231084e-06 -29.8114234742956 77.6944836112052 -0.38370064499658 0.701387370312694 UTP6 other 0.0228575727066513 1 0.0279437150503938 4.7215851840393 -0.38370064499658 0.000438846910210575 34.0239047780145 24.8050243138659 1.37165375641238 0.170875061725115 -161.814520102665 51.0416767312471 -3.17024303403427 0.0016302509131036 C17orf75 other 1 1 1 1.37165375641238 -3.17024303403427 0.00357355922059086 349.781797091488 123.453084869697 2.83331759154238 0.00481951862805899 -491.285416621913 346.942966266206 -1.41604086086286 0.157474263369624 CYTH1 other 1 1 1 2.83331759154238 -1.41604086086286 4.60181407811027e-06 320.635754576144 74.7862435869992 4.28736274476932 2.22666400002619e-05 -197.229082859602 153.888793689999 -1.28163382225811 0.200650717001111 PSMD11 essential 0.0264742363913684 1 0.190691504962242 4.28736274476932 -1.28163382225811 0.274907494547062 533.200008592358 635.047193165108 0.839622652191976 0.401578038362091 2639.67183640151 1784.687334045 1.47906682926845 0.13984126595388 LGALS3BP other 1 1 1 0.839622652191976 1.47906682926845 0.223376670546986 -45.7664774245754 27.0033329100223 -1.69484550581492 0.090817126715579 -46.9879556797908 56.0441938669147 -0.838408984726781 0.402259392331582 ASIC2 other 1 1 1 -1.69484550581492 -0.838408984726781 0.993933936596799 -5.93842052168754 275.139983287072 -0.0215832699077094 0.98279020789145 -62.7168035739971 571.028682754443 -0.109831266743858 0.912593496859855 CCL2 other 1 1 1 -0.0215832699077094 -0.109831266743858 0.897592745899133 8.2160974203777 21.0850838416145 0.389663967290566 0.696974442587889 -5.7460729211701 43.7602252787875 -0.13130812020649 0.895591859339929 CCL8 other 1 1 1 0.389663967290566 -0.13130812020649 0.000131610171393392 35.2519151443718 30.4390007249265 1.1581167024154 0.247447505749769 -242.873343607875 66.1269529371288 -3.67283434091981 0.000269539027008183 PEX12 other 0.642652466913932 1 1 1.1581167024154 -3.67283434091981 0.141237405037656 -50.8645390381835 59.2400129287303 -0.858617959779599 0.391020954754282 197.23857641781 130.791892040603 1.50803366585276 0.132266844828734 DHX58 other 1 1 1 -0.858617959779599 1.50803366585276 0.17115124400178 266.409341984139 375.219221940773 0.710009845993952 0.478075858305753 -1245.79483582482 828.420345327711 -1.5038197007728 0.13334848492856 KAT2A other 1 1 1 0.710009845993952 -1.5038197007728 0.000101916264246934 116.729954846348 145.898150934678 0.80007837041479 0.424099107879475 -1259.99880174769 322.118349787151 -3.91160206359021 0.000106246076969917 RAB5C other 0.504893173079312 0.842956374679325 1 0.80007837041479 -3.91160206359021 0.0018371632287495 256.009961224765 72.5684224162472 3.52784245131182 0.000463227289575688 55.0341623211652 158.94311533209 0.346250683498803 0.729320592955386 NAGLU other 1 1 1 3.52784245131182 0.346250683498803 5.42623170957755e-05 58.7823906939435 24.543814359806 2.39499817885715 0.0170396328743311 -163.738467709587 53.7571327388627 -3.04589287722958 0.00245998647875023 HSD17B1 other 0.277931588164562 1 1 2.39499817885715 -3.04589287722958 6.06810604616961e-05 189.552294151811 43.0721907703525 4.40080457394065 1.35702619175521e-05 170.593698342492 94.3400263000375 1.80828546517401 0.0712493660259113 MLX other 0.308927278810495 1 0.117301344015321 4.40080457394065 1.80828546517401 0.316981353597176 -155.387258187021 224.449759256463 -0.692303073533131 0.489114712296807 -729.227404726804 491.607132411448 -1.48335399681809 0.138701217115263 CNTNAP1 other 1 1 1 -0.692303073533131 -1.48335399681809 0.00798917601823955 41.9683940786922 60.8156575803415 0.690091922844856 0.490501866331236 447.689087662778 143.569858861993 3.11826654432474 0.00193913736008175 ABI3 other 1 1 1 0.690091922844856 3.11826654432474 0.000504474166016553 91.2098467587011 77.9436692670609 1.17020211668745 0.242557420466694 -567.734642362507 170.718221596412 -3.32556558435025 0.00095682795674112 EZH1 other 1 1 1 1.17020211668745 -3.32556558435025 0.0233270247482218 -43.9975385646376 183.807055708356 -0.239368061226375 0.810932162618832 -1201.50465868525 437.410939755131 -2.74685552985454 0.0062650571713162 PPP1R9B other 1 1 1 -0.239368061226375 -2.74685552985454 0.369922142173942 550.695903192139 666.284529207929 0.826517619802459 0.408960536577626 1996.51010992692 1585.5764673559 1.25916986725736 0.20863961224305 COL1A1 other 1 1 1 0.826517619802459 1.25916986725736 0.31299489015106 7.48333483682797 4.90395377875557 1.52597988774824 0.127736616803544 2.46216992924983 11.6700799249225 0.210981411017729 0.832999899497555 SGCA other 1 1 1 1.52597988774824 0.210981411017729 0.000341043217620745 129.140725806452 47.3984006695217 2.72457981666653 0.00669664210987812 -243.54489247312 107.238618271411 -2.27105586027536 0.0236293072148261 PTGES3L-AARSD1 other 1 1 1 2.72457981666653 -2.27105586027536 0.0672904799073923 710.659005376345 331.547144758441 2.14346290297302 0.032627342104147 -300.129838709681 750.123573654441 -0.400107194668624 0.689273071670829 VAT1 other 1 1 1 2.14346290297302 -0.400107194668624 0.0153013066204635 -1165.19206989248 821.67175786369 -1.41807486839018 0.156881590788555 -5191.72876344091 1859.02778872882 -2.7927117576822 0.00545630541892219 RND2 other 1 1 1 -1.41807486839018 -2.7927117576822 0.100115559646005 6.3966460513797 2.98777980810285 2.14093623433427 0.0328305692250448 0.295432921027595 2.23336953319834 0.132281253342126 0.894822579995793 ALOX12 other 1 1 1 2.14093623433427 0.132281253342126 0.000598549143536002 294.729057214023 147.985594167531 1.99160640515027 0.0470348334842359 -934.9215638472 334.814457467696 -2.79235720858143 0.00546165195384961 HDAC5 other 1 1 1 1.99160640515027 -2.79235720858143 0.0982991519867171 -146.876175055103 99.6847302724451 -1.47340695664903 0.141361257505284 -430.024090316199 233.885184928507 -1.8386119259655 0.06665070155122 MPP2 other 1 1 1 -1.47340695664903 -1.8386119259655 0.905579208185891 -49.642942163069 121.138054517307 -0.409804684092698 0.682150500314856 25.652707893738 284.220316397123 0.0902564187490915 0.928124899271704 DUSP3 other 1 1 1 -0.409804684092698 0.0902564187490915 6.13255363715972e-06 932.311766312885 187.700647901297 4.96701410856688 9.76363362476468e-07 376.953875825177 420.385244951662 0.896686742343968 0.370378668229337 EFTUD2 essential 0.03482677210543 1 0.00875993208813887 4.96701410856688 0.896686742343968 0.299602023355033 130.98789191446 143.766394176213 0.911116208102917 0.362735299372529 -139.01857609009 108.347558460923 -1.28307991490393 0.200142574972005 EFNB3 other 1 1 1 0.911116208102917 -1.28307991490393 0.00122197082772466 2725.64484113757 743.480060208302 3.66606313607647 0.000276769879183807 122.503286952178 528.484449213639 0.231801119473728 0.816801490541007 YWHAE other 1 1 1 3.66606313607647 0.231801119473728 1.01354731461945e-05 153.529989969911 34.1023860814841 4.50203072603386 8.63979697492039e-06 43.495918925608 26.5839978290752 1.63616921748451 0.102522496602096 RANGRF other 0.0563126888002567 1 0.0752439918545817 4.50203072603386 1.63616921748451 0.000136207354134395 237.300508300843 64.4806172243158 3.68018357323287 0.000262115571026457 -119.800220450918 49.4964630803326 -2.420379416939 0.015910182693427 DPH1 essential 0.663738436696908 1 1 3.68018357323287 -2.420379416939 8.43180636473469e-10 137.636834614289 23.5928759932318 5.83383029071036 1.05406062574419e-08 -60.981149123471 18.4297772405872 -3.30883810083034 0.00101417852648824 DHRS7B other 6.02030974442057e-06 1 9.80487194067244e-05 5.83383029071036 -3.30883810083034 0.246753444502631 893.371788098551 588.381952323597 1.51835348547064 0.12965006560778 -357.549349214736 1245.97949430593 -0.286962466757053 0.774277382836213 WSB1 other 1 1 1 1.51835348547064 -0.286962466757053 0.000196672638870009 39.4456944555728 14.5865986510381 2.70424211971896 0.00712224470835438 34.1926287433906 11.48898803119 2.97612188737297 0.00308668737763119 MYH3 other 0.936948451576723 1 1 2.70424211971896 2.97612188737297 0.598194699092943 -5.81866865184184 5.76286633019551 -1.00968308450153 0.313207152082634 -4.36658501833086 12.2036599652544 -0.357809462961372 0.720659059799664 VTN other 1 1 1 -1.00968308450153 -0.357809462961372 0.000958797270287879 196.391335670716 79.6178614295908 2.46667433845096 0.0140209742375955 -352.627515489168 168.601743017438 -2.09148202846692 0.0370629848973341 TNFAIP1 other 1 1 1 2.46667433845096 -2.09148202846692 0.00542033109002706 96.6924979587914 37.5095059470164 2.57781315742663 0.0102700709316749 -98.1591902406225 79.4315241433935 -1.23577120418111 0.217209016791993 IFT20 other 1 1 1 2.57781315742663 -1.23577120418111 0.102093535076852 22.4008693146355 149.262820150914 0.150076685486626 0.880773514371204 -639.438979876089 316.084496534708 -2.02300013726195 0.0436829035741436 TMEM97 other 1 1 1 0.150076685486626 -2.02300013726195 0.012536730421281 -109.085623795861 331.027904845296 -0.329536036688029 0.741908090948675 -720.026106421613 245.691104359495 -2.93061528743048 0.00355986989538635 PMP22 other 1 1 1 -0.329536036688029 -2.93061528743048 0.00813636493033189 -108.630133038759 81.9719030879423 -1.32521179753771 0.185794943799948 412.938267454333 173.586749140526 2.37885823370101 0.0177960112714747 UNC119 other 1 1 1 -1.32521179753771 2.37885823370101 0.0186143585778141 -2916.70630613318 3199.89654012507 -0.911500190571528 0.3625355633413 -19177.2943982838 6776.21986390156 -2.83008739141502 0.00486854263650417 ALDOC other 1 1 1 -0.911500190571528 -2.83008739141502 0.0102360616578676 305.026823879735 127.039526578591 2.40103873254781 0.0167665307838999 -316.533347741865 269.023623954059 -1.17660056425349 0.239996943870103 SUPT6H essential 1 1 1 2.40103873254781 -1.17660056425349 0.00176740815159545 43.4612410547024 104.63859417051 0.415346186550268 0.678092817584286 785.954332965115 221.586576771394 3.54694018210303 0.000431983433158424 RAB34 other 1 1 1 0.415346186550268 3.54694018210303 0.0418846633997226 134.599683745296 72.2382666059454 1.86327399686274 0.0630958557928315 -194.083040951039 157.935205126816 -1.22887763241386 0.2197805304502 PHF12 essential 1 1 1 1.86327399686274 -1.22887763241386 3.07707951102271e-08 57.2122318194471 76.1453016344109 0.751356033680643 0.452842845214295 -562.496154917806 123.959956095693 -4.53772470267397 7.35876408658268e-06 TMEM33 other 0.000204687329073231 0.0627187463099442 1 0.751356033680643 -4.53772470267397 0.543293359040037 -65.5622646973676 82.1636762435662 -0.797947069736932 0.425334594036185 -141.456414711848 129.58968233376 -1.09157158320309 0.275622902195998 GABRA4 other 1 1 1 -0.797947069736932 -1.09157158320309 2.65136763888669e-06 25.903571276187 46.3569955002693 0.558784515619365 0.57659632111855 -275.912005233891 73.3027044577596 -3.76400853522238 0.000190154121315079 SLAIN2 other 0.0155635280402649 1 1 0.558784515619365 -3.76400853522238 2.70400508057694e-09 73.1020928446465 163.227271576739 0.447854651606294 0.654481051952429 -1257.18678442918 258.105606688136 -4.87082322837031 1.55874526905735e-06 OCIAD1 other 1.89361475792803e-05 0.0136608435380186 1 0.447854651606294 -4.87082322837031 7.28109980320073e-06 103.024091963318 53.6274723950807 1.92110661498879 0.0554029904048741 -264.043837904549 92.4491209776681 -2.85609895596877 0.00450425080377583 DCUN1D4 other 0.0409925918920201 1 1 1.92110661498879 -2.85609895596877 0.0128423949947206 -229.52205195687 166.740472627147 -1.3765227382443 0.169400273022977 -850.600348077082 287.433548898522 -2.95929390057869 0.00325964037255295 USP46 other 1 1 1 -1.3765227382443 -2.95929390057869 0.0453465137929561 57.3328805501312 32.6872258959036 1.75398428525916 0.0801695392406681 -33.2012904321248 56.3474793784262 -0.589224057550951 0.556030817151203 CHIC2 other 1 1 1 1.75398428525916 -0.589224057550951 0.492267884159436 12.4141252632398 10.4189560201152 1.19149416114942 0.234126161932588 11.7679588175649 18.4059150410439 0.639357445219278 0.522935691362275 NMU other 1 1 1 1.19149416114942 0.639357445219278 0.0982979932023903 202.831576197787 109.377211767074 1.85442262534294 0.064371204078838 -11.8209798836856 209.429151817614 -0.0564438130083257 0.955014780644994 KIAA1211 other 1 1 1 1.85442262534294 -0.0564438130083257 9.34223074784218e-18 41.638785533566 67.6591125017863 0.615420214571492 0.538597604859993 -611.150180176522 95.3436495800774 -6.40997258724849 3.77725516110441e-10 LAMTOR3 other 7.79515733599952e-14 3.5562857341798e-06 1 0.615420214571492 -6.40997258724849 2.19425269314883e-09 -29.3396936177429 54.4645602252431 -0.538693298842513 0.59037216881864 -413.26402538469 79.3020412216346 -5.21126592731319 2.8946853389875e-07 NFKB1 other 1.54190136747568e-05 0.00259769062320738 1 -0.538693298842513 -5.21126592731319 2.086197916735e-10 -3.64371722840803 44.2600394323728 -0.082325214236997 0.934425712018575 -336.530058643634 64.4439513882357 -5.22205810466595 2.74025836147269e-07 MANBA other 1.51979518234145e-06 0.00246020395693018 1 -0.082325214236997 -5.22205810466595 5.77828275072299e-25 254.77843833346 157.688842709257 1.6157036474877 0.106878435415985 -1689.51855570137 229.599707644853 -7.35853966467036 9.25569932405932e-13 UBE2D3 essential 5.11320240611478e-21 8.89935490008304e-09 1 1.6157036474877 -7.35853966467036 0.000200340011370006 -471.67166030439 235.946330080604 -1.99906334691986 0.046218899548776 -1357.8785072753 336.801149198821 -4.03169202511752 6.53119356436246e-05 MAPK10 other 0.953418114109858 0.526806072901476 1 -1.99906334691986 -4.03169202511752 1.47699279757e-11 137.004711405173 38.6811707141515 3.54189671294127 0.00043988771515444 -120.767872298809 52.6032145110077 -2.29582685053472 0.0221573405436224 ELF2 other 1.1098123880941e-07 1 1 3.54189671294127 -2.29582685053472 1.73083398097477e-13 153.82150856987 54.065597334161 2.84509033756072 0.00464808389580213 -255.823334458576 73.2067880084428 -3.49453023986071 0.000523259450334469 NDUFC1 other 1.35541609050134e-09 1 1 2.84509033756072 -3.49453023986071 0.126113557307122 -89.4849863058368 99.2725546947652 -0.901407106737382 0.367867290235165 -262.750782820683 134.418654836619 -1.95471962682595 0.0512519164272436 TBC1D9 other 1 1 1 -0.901407106737382 -1.95471962682595 2.07324100253196e-14 72.0304818092459 34.6926872653937 2.07624394323287 0.0384554083713757 -193.823008849554 47.1233466997643 -4.11309939602663 4.66546915797119e-05 ZNF330 other 1.65112913441646e-10 0.380702283290449 1 2.07624394323287 -4.11309939602663 0.0647793456401986 -23.2784206943503 32.7045670746207 -0.711778897462147 0.476981494356384 -92.2518720217838 44.4228675955108 -2.07667530294929 0.0384153477642724 INPP4B ts 1 1 1 -0.711778897462147 -2.07667530294929 2.16810692836854e-07 173.707283866578 190.968458385909 0.909612431994137 0.363528345207 -845.058202859084 259.393940988117 -3.25781781810315 0.00121028567284239 GAB1 other 0.00137111082150026 1 1 0.909612431994137 -3.25781781810315 0.00311924893490557 -26.0549361443369 94.0793227922756 -0.276946467842518 0.781951861343214 -323.724032649754 126.274675380037 -2.56364969203424 0.0106905506020478 KLHL2 other 1 1 1 -0.276946467842518 -2.56364969203424 8.58349193966259e-12 -11341.2329887157 4464.78052572113 -2.54015464441759 0.0114247597007229 -39641.4701600081 5992.69525752618 -6.61496512945869 1.08594335555717e-10 CPE other 6.47452797008749e-08 1.02610787666597e-06 1 -2.54015464441759 -6.61496512945869 0.000280347112881505 1129.41103810774 566.946184578867 1.99209566768084 0.0469809284563663 -1161.11467993244 796.972525012825 -1.45690678598206 0.145858620452664 RPL34 essential 1 1 1 1.99209566768084 -1.45690678598206 0.0240950024834287 7.55192814500244 261.226086876938 0.0289095481821465 0.976949897984567 -922.763957573167 414.9121690489 -2.22399829749128 0.0266577276998372 WFS1 other 1 1 1 0.0289095481821465 -2.22399829749128 0.000111832300826167 13.6786624366491 34.2365662592198 0.399533712962979 0.689695181753633 -178.263307245702 54.3822240884803 -3.27797014987224 0.00112904383134007 GRPEL1 essential 0.551333243073001 1 1 0.399533712962979 -3.27797014987224 1.06360171625267e-05 49.6998685939556 25.5828308128058 1.94270403293594 0.0526924137524919 -77.789281021213 35.9625195908192 -2.16306537768482 0.0310764800529348 GAR1 essential 0.0589448071147227 1 1 1.94270403293594 -2.16306537768482 6.99985007974742e-10 41.9220578418567 24.8959210768674 1.6838926229088 0.0929231177695952 -110.959822218165 33.1130858443319 -3.35093572190158 0.000875996078075581 FRG1 other 5.0144562163245e-06 1 1 1.6838926229088 -3.35093572190158 9.45462350832983e-16 279.578588173107 367.77466947101 0.760189897186883 0.447551952301628 -2671.12628243183 498.229693128105 -5.36123462586368 1.34292262559227e-07 CLCN3 other 7.69322714872799e-12 0.00121534497616101 1 0.760189897186883 -5.36123462586368 0.000377411881659491 34.1283695656887 24.8152741161194 1.37529690004592 0.169745630696609 -53.091286468873 33.6176127234302 -1.57926997689132 0.114999332422397 AADAT other 1 1 1 1.37529690004592 -1.57926997689132 1.01052711133335e-07 173.447097409277 50.1066561827297 3.46155801689794 0.000590030749142827 -46.7970150834954 68.1240215429815 -0.686938528048725 0.492486666249186 GALNT7 other 0.000651385775965475 1 1 3.46155801689794 -0.686938528048725 3.92580696669372e-05 385.501680523615 136.814327329985 2.81769963750812 0.00505682007489154 -316.054133653611 222.738173037903 -1.41894911564992 0.156628311418868 DHX15 essential 0.204887865591745 1 1 2.81769963750812 -1.41894911564992 0.531696211202905 36.1464709004069 70.7996235339227 0.510546089035175 0.609927319791932 -63.5196526607513 115.264088969878 -0.551079293025525 0.581861595826497 SOD3 other 1 1 1 0.510546089035175 -0.551079293025525 6.29492429724245e-10 62.9048292941803 20.4469104746522 3.07649556015627 0.00222639890134267 -107.20210042176 33.2882350282584 -3.22042007726622 0.001375800751787 SEPSECS essential 4.51975564542008e-06 1 1 3.07649556015627 -3.22042007726622 0.454723417405657 16.0711034557133 22.6583190703686 0.709280481301468 0.478528676972303 -15.8065816879579 35.9910446574426 -0.439180963998201 0.6607474919078 CPZ other 1 1 1 0.709280481301468 -0.439180963998201 1.29546551700941e-05 35.5603658793296 431.327977979412 0.0824439120455731 0.934331553022722 -1814.68796401556 569.714486143672 -3.18525859557997 0.00155005075788273 TRIM2 other 0.0712376487803475 1 1 0.0824439120455731 -3.18525859557997 0.0233910025439331 10.1041967132905 8.50347205657397 1.18824365459977 0.235384272918795 -18.1631008969184 13.5079771339666 -1.3446203466873 0.179446960073295 SLC2A9 other 1 1 1 1.18824365459977 -1.3446203466873 0.335986264278328 -10.5498425196934 158.976491047423 -0.0663610226278449 0.947120749815759 -219.794530183735 209.960194469624 -1.0468390484156 0.295752475358696 FBXW7 ts 1 1 1 -0.0663610226278449 -1.0468390484156 4.06196523283753e-10 63.9818831002819 9.75556127912726 6.55850353143451 1.541488474828e-10 77.2824867080628 13.2160007359482 5.84764546038881 9.78875075684395e-09 NEIL3 other 2.93639466681825e-06 9.03795357379401e-05 1.46456819993409e-06 6.55850353143451 5.84764546038881 0.0189475798685678 11.3658234565718 13.586871604724 0.836529834625065 0.403315142034272 -39.4968763674622 22.1198687125624 -1.78558367053196 0.0748616353017815 TBC1D19 other 1 1 1 0.836529834625065 -1.78558367053196 0.0051043528644434 282.42560000001 196.542925397804 1.43696650199125 0.151443077795837 -510.117333333324 319.600237362117 -1.5961106210173 0.111186966021091 NSD2 other 1 1 1 1.43696650199125 -1.5961106210173 0.000122447284970515 439.319529783202 190.518493454221 2.30591540914512 0.0215837377899793 -193.638220149234 252.566187209373 -0.766683071430743 0.4436848902237 SH3D19 other 0.600236590925464 1 1 2.30591540914512 -0.766683071430743 0.0118842786366315 224.913310993508 132.408188200444 1.69863596844197 0.0901012008100717 -227.983221386871 212.845569780215 -1.07112035088298 0.284707878355211 STIM2 other 1 1 1 1.69863596844197 -1.07112035088298 1.20119672919038e-06 419.991421987892 99.924151793027 4.20310219753299 3.19424048168041e-05 -58.4153770300429 165.770628779436 -0.352386773580783 0.724718103104994 MFSD10 other 0.00722519832608014 1 0.271670152966919 4.20310219753299 -0.352386773580783 0.0288771245749297 -79.8377255665288 106.654867693349 -0.748561479594872 0.454525169799045 -337.557467446283 145.546326910332 -2.31924415141197 0.0208431060056445 GLRB other 1 1 1 -0.748561479594872 -2.31924415141197 0.00907391247243202 28.4226886740652 10.8687199859217 2.61509071085475 0.00922958006203819 2.30658886313249 17.4714187213488 0.132020696196469 0.895028823441611 BST1 other 1 1 1 2.61509071085475 0.132020696196469 5.69124263848009e-06 -0.0556389852820029 183.333194803048 -0.000303485603585183 0.999757992014192 -864.622669618285 250.156827804835 -3.45632248859839 0.000601170470952998 RAPGEF2 other 0.0324059355835056 1 1 -0.000303485603585183 -3.45632248859839 0.0506122072455868 22.1875415065107 9.89551905171172 2.24218066688202 0.0254505598858128 6.95120343724248 16.4163156340708 0.423432613759922 0.672187972372706 HGFAC other 1 1 1 2.24218066688202 0.423432613759922 1.21542545223854e-09 95.9446599959154 23.2928030149166 4.11906887867779 4.55066407009949e-05 -18.8892832346343 30.7710137102577 -0.613866134294346 0.539623203862993 SNX25 other 8.62708985998915e-06 1 0.384394594001304 4.11906887867779 -0.613866134294346 0.000658976515703868 -37.2368797222762 64.0006964180377 -0.58181991456864 0.56098799885378 -260.375406711588 84.5482746616758 -3.07960638763468 0.00220346866029079 LRP2BP other 1 1 1 -0.58181991456864 -3.07960638763468 8.74609086398311e-24 176.101490708597 42.1955827280458 4.1734579622608 3.62147486537448e-05 -227.77269212443 55.742576529133 -4.08615292487221 5.21887674125352e-05 UFSP2 other 7.69218691487314e-20 0.424503434133561 0.307101068583756 4.1734579622608 -4.08615292487221 5.13708051227599e-05 150.831352107308 100.174850658394 1.5056808282316 0.132871575678779 -431.864246045731 162.501708776286 -2.65759818341525 0.0081584444291801 KLF3 other 0.263686342695127 1 1 1.5056808282316 -2.65759818341525 3.87038684917137e-07 -192.434301697286 181.245846659306 -1.06173082166684 0.288944303341651 -1494.64944724082 294.01351334357 -5.0836079955762 5.50231673828473e-07 KLHL5 other 0.00240970285229409 0.00489266004368278 1 -1.06173082166684 -5.0836079955762 0.00931606535159378 -32.8263894448637 46.2876009862555 -0.709183209875385 0.478588106349792 -157.689846764769 60.9581320793101 -2.58685496726844 0.0100070184666332 FAM149A other 1 1 1 -0.709183209875385 -2.58685496726844 0.000228918084921794 258.899345480274 64.5045144930526 4.01366241595631 7.03677596597005e-05 147.105663504242 105.015446783041 1.4008002442551 0.161985119356217 NCAPG essential 1 1 0.589541090428971 4.01366241595631 1.4008002442551 0.00229415552594907 96.0945267306603 70.8392877728517 1.35651458042309 0.175635874883621 -220.22006056368 114.914125011664 -1.91638809016148 0.0559677051967948 UGDH other 1 1 1 1.35651458042309 -1.91638809016148 0.171420355765441 100.874933663541 96.2848794387851 1.04767159964794 0.29537035893388 -112.898370993822 156.754914166578 -0.720222211814355 0.471774117908157 PPARGC1A other 1 1 1 1.04767159964794 -0.720222211814355 0.71822636231692 5.57738325092221 28.4250902365782 0.196213387697361 0.844534152315155 25.6975245271172 35.6340683024854 0.721150453801114 0.471201694390952 HTATIP2 other 1 1 1 0.196213387697361 0.721150453801114 0.000147918918800236 63.5773733532524 26.7174484817819 2.3796199474888 0.017760746873347 -37.1165082167594 33.4426482221095 -1.10985553447352 0.267674434003445 CCDC34 other 0.717998431856344 1 1 2.3796199474888 -1.10985553447352 2.90234135517321e-14 89.4137944500598 30.5148055726451 2.9301774260759 0.00356561522416099 -150.330214554811 38.2604914195212 -3.9291239860581 9.9106741282601e-05 ELP4 other 2.30765161149822e-10 0.789186980833352 1 2.9301774260759 -3.9291239860581 5.13017969138843e-13 309.653260902644 81.0732511443118 3.8194257234295 0.000153166651406822 -379.434312770729 105.725573661269 -3.58886028830061 0.000369819427125211 MTCH2 other 3.97588926082603e-09 1 1 3.8194257234295 -3.58886028830061 0.00864513150755845 214.944448742231 101.548829529615 2.11666101655605 0.0348558460324564 -106.66044495425 133.25508623803 -0.800423068007517 0.423902640162632 FNBP4 essential 1 1 1 2.11666101655605 -0.800423068007517 0.500052594330328 8.66833247010168 27.567552385256 0.314439684342008 0.753336842003012 -63.8971634680446 65.7429136211459 -0.971924728439361 0.331624421124344 LPXN other 1 1 1 0.314439684342008 -0.971924728439361 0.139894700257531 -188.498327759198 201.828745624475 -0.933951837117993 0.350843316111328 -952.023411371237 485.133762843815 -1.96239364127236 0.0503493358566689 DTX4 other 1 1 1 -0.933951837117993 -1.96239364127236 0.00330968415890016 219.508792454043 87.0747728521713 2.52092294086954 0.0120588200923221 -281.958485303091 209.300771660852 -1.34714498692806 0.178630066290904 OSBP other 1 1 1 2.52092294086954 -1.34714498692806 0.971690074764325 9.28558386207509 177.040865954713 0.0524488163340227 0.958194989635972 101.39277243303 425.551381256378 0.238262115690197 0.811789227987646 MS4A6A other 1 1 1 0.0524488163340227 0.238262115690197 0.839860095879271 -5.22624110546771 72.7353459865263 -0.0718528390094664 0.942751819482876 -101.104229461717 174.833232902535 -0.57828953788254 0.563365864022711 MS4A4A other 1 1 1 -0.0718528390094664 -0.57828953788254 0.0141381182851861 105.115664721581 35.8500022497772 2.93209646094889 0.00354367415370673 87.1738318179762 86.8404751943125 1.0038387240848 0.316011867068225 CCDC86 essential 1 1 1 2.93209646094889 1.0038387240848 1.92176535731126e-07 632.85099742162 137.655486626801 4.59735396626323 5.60974949690634e-06 -550.064920613381 333.446781634443 -1.64963331754815 0.0997365262941991 PRPF19 essential 0.00121820705999961 1 0.0491862835888748 4.59735396626323 -1.64963331754815 0.0551189567117303 15.5415479259953 84.2834611706523 0.184396175834873 0.853788207968166 477.717252453971 204.162213661404 2.3398906383639 0.0197386910536252 TMEM109 other 1 1 1 0.184396175834873 2.3398906383639 0.415710302548919 -33.3710959895482 27.8435298137495 -1.19852246510315 0.231361751689131 -42.5585824788292 33.6431459175314 -1.26500008599528 0.206543899661373 CCKBR other 1 1 1 -1.19852246510315 -1.26500008599528 0.0309362574867126 6.72322057952757 3.1959375642132 2.10367707267233 0.0359762445671555 1.73723413254136 3.86162941751189 0.449870752657744 0.653026195258584 HPX other 1 1 1 2.10367707267233 0.449870752657744 6.55616076181124e-14 91.4952442268103 34.2482496913443 2.67153051765838 0.00783203174001389 -133.213770125098 41.3819249747913 -3.21912937124718 0.00138141488094925 TRIM3 other 5.17674453752616e-10 1 1 2.67153051765838 -3.21912937124718 3.2898390004221e-24 385.439636100276 201.052113343475 1.91711307924327 0.0558737984695193 -1508.56999216246 243.830684285613 -6.18695713618793 1.40946478773398e-09 RNF141 other 2.89867714327191e-20 1.31770863005249e-05 1 1.91711307924327 -6.18695713618793 1.76955335006227e-11 2738.80349613579 965.264956879846 2.83735929354442 0.00476002670577841 -3017.76158020575 1170.64780388977 -2.5778560982889 0.010267310207026 EIF4G2 essential 1.32645719120668e-07 1 1 2.83735929354442 -2.5778560982889 3.26492253927228e-07 45.6041747274221 62.3009121747818 0.731998507493472 0.464560959201819 -249.069446511304 75.5568981323913 -3.2964488043816 0.00105883775564703 GALNT18 other 0.00204122957155303 1 1 0.731998507493472 -3.2964488043816 0.046248625000215 42.2689974700507 98.8456517146182 0.427626271230296 0.669134845906322 -199.206495564972 124.190707365986 -1.60403704745732 0.109431649156354 HIPK3 other 1 1 1 0.427626271230296 -1.60403704745732 0.314119992944812 -221.066144420401 224.25265487269 -0.985790534100486 0.324783894955116 -429.343732927546 281.753373610677 -1.5238281885519 0.128278277595518 KIAA1549L other 1 1 1 -0.985790534100486 -1.5238281885519 5.12733192252609e-20 94.5987441704489 53.8184071403831 1.75773957641838 0.0794951518689527 -430.032460239494 67.6180078347984 -6.35973276956239 5.12057570148277e-10 FBXO3 other 4.38079239460629e-16 4.81487733210425e-06 1 1.75773957641838 -6.35973276956239 1.13995833437932e-17 112.886302038346 38.9118809236479 2.90107543914029 0.00390665099688993 -234.66557536296 48.7819751342723 -4.81049762165315 2.07608130850712e-06 PDHX other 9.50611255038919e-14 0.0181117333354161 1 2.90107543914029 -4.81049762165315 0.000346992725125918 -4638.5078961057 3982.9150867894 -1.16460125185465 0.244815801434962 -18440.0328330446 4993.19128537937 -3.69303553161263 0.000249660690190764 SLC1A2 other 1 1 1 -1.16460125185465 -3.69303553161263 4.06161452253801e-23 235.082779796015 55.5465280548041 4.23217774410804 2.82342478055065e-05 -340.918401135564 69.7792562780815 -4.8856697436979 1.45031783700756e-06 COMMD9 other 3.55756816029104e-19 0.0127207377483933 0.240725196789748 4.23217774410804 -4.8856697436979 0.843359729455703 -32.4315083637543 84.1581983469972 -0.385363624706344 0.700155106363683 -109.921014751073 203.860088848162 -0.539198306898337 0.590023996466482 SLC15A3 other 1 1 1 -0.385363624706344 -0.539198306898337 0.702290675116928 1.13859529092891 24.2314829408464 0.0469882629019625 0.962544346311375 22.5299461248105 31.7430938975275 0.709758985609322 0.478237410274894 ACCS other 1 1 1 0.0469882629019625 0.709758985609322 0.0436267595013858 -7.8160997987097 240.808296455646 -0.0324577679164361 0.974121950523164 -685.665287292767 325.74281155315 -2.10492837592792 0.0358731404920897 MDK other 1 1 1 -0.0324577679164361 -2.10492837592792 4.95704826350198e-13 157.313348250155 45.18628193878 3.48144041732155 0.000549377003544844 -234.966926703122 61.1237517104508 -3.84411820491947 0.000139124703221979 AMBRA1 other 3.84468663317214e-09 1 1 3.48144041732155 -3.84411820491947 5.98609487373333e-06 381.535977015696 234.050360405457 1.63014479599494 0.103793069085165 -931.091568589526 308.442132817775 -3.01869125363495 0.00268762457080932 MADD other 0.0340129910725528 1 1 1.63014479599494 -3.01869125363495 6.17453110196609e-20 249.641102894182 73.2619951748129 3.40751166138058 0.00071643682930789 -566.701892936488 95.5391125691851 -5.93162190538569 6.11416084556206e-09 PTPMT1 essential 5.27057974863826e-16 5.66415860732869e-05 1 3.40751166138058 -5.93162190538569 1.09952584413025e-16 664.74745567958 119.675092519188 5.55460156066308 4.84154681639424e-08 -17.56832567301 139.211655009034 -0.1261986697297 0.899632704864616 CARS other 9.0710882140746e-13 1 0.000445567553512762 5.55460156066308 -0.1261986697297 0.0051648796015607 19.8989647874313 21.5149276336992 0.924891086143519 0.355533003454464 -29.3171885732615 24.5950099127174 -1.19199742863703 0.233909158318253 SLC22A18 other 1 1 1 0.924891086143519 -1.19199742863703 3.47604526237287e-13 2364.81288945939 1765.31251272064 1.33960014015581 0.181071604976373 -7306.88395235952 2017.21337374991 -3.6222662646621 0.00032631695531758 CD81 other 2.70436321412609e-09 1 1 1.33960014015581 -3.6222662646621 4.33765398138757e-25 618.299390238861 118.324022197406 5.2254764396643 2.69563001056739e-07 -588.70256793714 148.112627335099 -3.97469532834107 8.24334547902095e-05 C11orf58 other 3.84229389671311e-21 0.660127105959998 0.00244844073859836 5.2254764396643 -3.97469532834107 3.55238319133989e-08 2314.68063125432 542.578537656636 4.2660748087296 2.44168646958378e-05 -178.731406238185 679.281820178456 -0.263118194729885 0.792583774843167 RPS13 essential 0.000235061195770961 1 0.208813026878805 4.2660748087296 -0.263118194729885 8.87559370998175e-17 384.637154899373 97.9335939645149 3.92753027157097 9.97428411092818e-05 -247.303950420232 113.399236461684 -2.18082553407484 0.0297301098155666 NUP98 essential 7.32946528570293e-13 1 0.82906249530035 3.92753027157097 -2.18082553407484 0.000158600614069682 91.2082133623216 42.9789839621921 2.12215843544733 0.0343863630793927 -71.413275649312 53.8873270427819 -1.32523321471514 0.185786260957746 HPS5 other 0.767151170255052 1 1 2.12215843544733 -1.32523321471514 1.28229919832992e-15 173.39616456525 38.3423982431234 4.52230878897482 7.88982675817423e-06 -119.543193761226 48.0739459906579 -2.48665241219135 0.0132674907793971 GTF2H1 essential 1.04161163880339e-11 1 0.0687992893312793 4.52230878897482 -2.48665241219135 0.336365914618643 -211.100018927383 146.26334199607 -1.44328726560245 0.149657643233193 -130.753778258745 183.725781148185 -0.711678989424377 0.477044181707637 PTPN5 other 1 1 1 -1.44328726560245 -0.711678989424377 1.96975116312596e-17 357.343526011563 38.9952672255615 9.16376656542883 1.95126434285377e-18 267.952040462431 77.7291722977147 3.44725194597639 0.000621034199588929 PSMD9 other 1.63765111702292e-13 1 1.90384861932243e-14 9.16376656542883 3.44725194597639 1.09888784002308e-07 36.611490362226 58.5487356417414 0.625316498485144 0.53208900777969 -368.351775917491 88.5668260780317 -4.15902649139708 3.84706951170307e-05 PRPF40B other 0.000705376104510812 0.315498170654768 1 0.625316498485144 -4.15902649139708 5.22092903727095e-08 42.129417060545 37.4297307899879 1.12556024773265 0.260968069784928 -255.590336177438 62.6095791583988 -4.08228803983507 5.30114678294988e-05 PRDM4 other 0.00034202306123162 0.430930221985996 1 1.12556024773265 -4.08228803983507 1.4650669491868e-08 134.940981038304 31.0564196219499 4.34502697609517 1.73347294871389e-05 -114.505303153075 58.2804496944508 -1.96472923173031 0.050078749255964 COQ5 other 9.92729364768976e-05 1 0.149113343048369 4.34502697609517 -1.96472923173031 0.00076634996367241 183.322951012994 176.861796124376 1.03653222476647 0.300527127559925 1065.01162498524 295.859317357006 3.59972312009401 0.000355051421662431 SELPLG other 1 1 1 1.03653222476647 3.59972312009401 0.000129279201183844 21.9472523518274 600.257549193532 0.0365630592756632 0.970850132298688 -3484.12275227471 1004.19051738823 -3.4695834026958 0.000573143274221217 CORO1C other 0.631658176984259 1 1 0.0365630592756632 -3.4695834026958 4.81313426156195e-05 -637.16732954546 637.012247838363 -1.00024345168813 0.317746232361969 -4006.66967921403 973.365499066928 -4.11630541975736 4.60347265402704e-05 ASIC1 other 0.24787641447044 0.375735438021687 1 -1.00024345168813 -4.11630541975736 0.339933216701947 -26.1118065134785 47.7532953300552 -0.546806379182885 0.584790855630234 -114.277099753348 79.8830367410837 -1.43055527700759 0.153272347867474 DAO other 1 1 1 -0.546806379182885 -1.43055527700759 0.0113788890436573 76.7985032635616 95.0793094070162 0.807730974725553 0.419683910091609 -302.025556032981 159.041366929543 -1.89903772750383 0.0582163294802162 KCTD10 essential 1 1 1 0.807730974725553 -1.89903772750383 4.2617725339512e-05 -117.918323667268 178.808040411974 -0.659468799029306 0.509942945102341 -1087.37129390794 276.094745751671 -3.93839908451558 9.54803633232368e-05 SLC11A2 other 0.221356465413426 0.761169456412844 1 -0.659468799029306 -3.93839908451558 0.00064148735591329 818.278753173794 315.928589715455 2.59007503534513 0.00991605760181347 -849.506353579533 592.871313051711 -1.43286803540356 0.152610530089777 MLEC other 1 1 1 2.59007503534513 -1.43286803540356 0.00274376527293526 32.443112761648 48.6463761235476 0.666917360488518 0.505176089369575 -194.108710330856 81.3719220628538 -2.38545072317355 0.0174824200076767 MVK essential 1 1 1 0.666917360488518 -2.38545072317355 1.59808498823283e-09 -53.4399397592312 72.7923158425711 -0.734142596518106 0.463256448219366 -623.164227652854 112.397495598772 -5.54428925958793 5.12193456427776e-08 CSRNP2 other 1.12824800169238e-05 0.000467735064409845 1 -0.734142596518106 -5.54428925958793 0.113400274215486 -183.286114445792 258.621944360401 -0.708702870899365 0.478886762260016 -1039.64385754303 499.083841444557 -2.08310462333116 0.03782245968025 CAMKK2 other 1 1 1 -0.708702870899365 -2.08310462333116 9.46655232201968e-06 -16.1457770640187 40.5133219585237 -0.398530070690037 0.690434143822612 222.309596807554 61.3086389501286 3.62607294199421 0.000321685799405773 BIN2 other 0.0527949622999037 1 1 -0.398530070690037 3.62607294199421 2.87712254762311e-07 32.5149983093225 783.11420615898 0.0415201231871429 0.966900300827131 -6345.3900763408 1361.55197180045 -4.66040974399968 4.20216081734471e-06 ATP5B essential 0.00180712067216207 0.03619321111979 1 0.0415201231871429 -4.66040974399968 2.97359877317123e-13 589.562561774956 214.686950196195 2.7461499696939 0.00628004377026389 -1744.73278754616 373.26284986345 -4.6742738747894 3.94075327457952e-06 PTGES3 other 2.31732552393234e-09 0.0339771747334247 1 2.7461499696939 -4.6742738747894 0.0018360996558021 -1.18109826589689 139.613645835527 -0.00845976235939208 0.993254018462641 -907.734930635837 278.291544188939 -3.26181283474267 0.00119355936811363 BCL7A other 1 1 1 -0.00845976235939208 -3.26181283474267 0.00120069330835827 61.0231791907516 84.4076806485402 0.722957658851475 0.470091762700102 -505.645832369941 168.249626664442 -3.00533108093253 0.00280529196531635 RSRC2 essential 1 1 1 0.722957658851475 -3.00533108093253 0.0610402754894478 9.96784946187467 4.80383615379186 2.074976985634 0.0386028356756287 1.46676042575175 8.06661921305286 0.181830874497998 0.855804020156616 CYP27B1 other 1 1 1 2.074976985634 0.181830874497998 0.0174398957179233 0.941695526049142 63.2923589748847 0.0148785025760032 0.988135885166458 -229.72683475394 100.781511964418 -2.27945414070635 0.0231202660800298 LIN7A other 1 1 1 0.0148785025760032 -2.27945414070635 0.994799797114927 -1.74184888912865 38.0046110783929 -0.0458325671465419 0.963464589919963 -6.21408047915178 61.4514758342107 -0.101121745162259 0.919500088910631 KRT18 other 1 1 1 -0.0458325671465419 -0.101121745162259 0.172057769214193 -26.2222917971207 154.948489990114 -0.169232315841179 0.865692039994183 -394.786474639951 246.727146068356 -1.60009338628095 0.110298881801572 ACSS3 other 1 1 1 -0.169232315841179 -1.60009338628095 0.00413384481921863 -270.756896649793 297.784394940848 -0.9092380300975 0.36372453298991 -1453.62819012151 464.299071550617 -3.13080141484419 0.00185999959459668 TNS2 other 1 1 1 -0.9092380300975 -3.13080141484419 0.689729135327358 4.51872853786379 6.95545080667632 0.649667241342057 0.516257333132902 -1.4646439544549 11.958935165246 -0.122472773220756 0.902582362473788 GLI1 og 1 1 1 0.649667241342057 -0.122472773220756 0.0205278189887262 -108.739382100177 88.0061025579385 -1.23558911188675 0.217278190912806 -403.702941349991 145.209750218861 -2.78013660061758 0.00566934631893023 PPM1H other 1 1 1 -1.23558911188675 -2.78013660061758 2.1871777647284e-08 178.346253229975 109.97479510023 1.62170116404793 0.105586930785224 -702.017854066693 182.368806349151 -3.84944041758248 0.000136021175232885 METAP2 essential 0.000146737756235629 1 1 1.62170116404793 -3.84944041758248 0.00148995140839757 149.46126875659 67.9426732865923 2.19981436594555 0.0283429085152472 -124.560643999432 112.674251480383 -1.10549342341199 0.269554089168621 LTA4H other 1 1 1 2.19981436594555 -1.10549342341199 0.0395205979958553 202.566836064464 95.4288714497375 2.12269969231645 0.0343406867589529 376.339203665907 158.256602810751 2.37803160804575 0.0178344415264654 ELK3 other 1 1 1 2.12269969231645 2.37803160804575 0.972921086901202 6.35600945307234 50.35687094357 0.126219308983572 0.899616244899197 -7.44079553127479 84.2331064361828 -0.0883357606775685 0.929650190853091 TRPV4 other 1 1 1 0.126219308983572 -0.0883357606775685 0.000218234699487808 461.275770875536 111.260710576954 4.14589991816107 4.06537724635886e-05 446.878849262374 186.108372116607 2.40117542365252 0.016758436385064 ARPC3 essential 1 1 0.34405287635935 4.14589991816107 2.40117542365252 0.00095337260522497 48.3210105784384 21.9319420811487 2.20322534136054 0.0280987619422403 -44.590673787162 36.6860683965806 -1.21546613567667 0.224843093591185 GPN3 essential 1 1 1 2.20322534136054 -1.21546613567667 9.75678734832651e-10 162.71854602746 38.8397084728179 4.1894893763515 3.3826563717816e-05 -113.220929756715 64.9680815435759 -1.74271622413192 0.0820850075377698 VPS29 essential 6.94878394947814e-06 1 0.287322832219129 4.1894893763515 -1.74271622413192 0.0127048008174244 -192.924487958588 103.76910324071 -1.85917081225099 0.0636733252685244 -514.512788247089 173.576986700721 -2.96417628872775 0.00320054399210717 CUX2 other 1 1 1 -1.85917081225099 -2.96417628872775 0.906278967434293 21.4739477830294 96.4190967172464 0.22271467493626 0.823861398918079 71.2725328913715 161.282460249875 0.44191124553128 0.658771535241941 SH2B3 other 1 1 1 0.22271467493626 0.44191124553128 6.24933563174687e-45 358.74326092646 22.4323466861283 15.9922305920984 1.30450461094466e-45 49.8771918345989 113.082502120447 0.441069050466122 0.659382141428526 MANSC1 other 5.90499723843762e-41 1 1.28493704178049e-41 15.9922305920984 0.441069050466122 3.41403684433716e-09 241.044875840941 37.7459623221421 6.38597775793207 4.37850740428896e-10 161.047654602277 190.279150195706 0.846375729745672 0.397808530632227 DUSP16 other 2.37787666208083e-05 1 4.14250585519779e-06 6.38597775793207 0.846375729745672 0.000137638711586014 305.696791018204 77.6643655006462 3.93612680728925 9.64227672034947e-05 -166.738945560421 241.320079914886 -0.690945177952993 0.489969377597169 CREBL2 other 0.670438164135474 1 0.801851732064262 3.93612680728925 -0.690945177952993 1.8181136750583e-05 97.8797142187862 42.1472273634996 2.32232866410453 0.0206728053724173 -154.012749723923 72.3777192440018 -2.12790277633246 0.0339029704237626 ACAD10 other 0.0984326743676563 1 1 2.32232866410453 -2.12790277633246 0.00424123645000566 -1862.90161630361 938.634883373135 -1.98469250323297 0.0478021785425439 -5355.12011846206 1611.87950693623 -3.32228314549439 0.000967697081993684 ALDH2 other 1 1 1 -1.98469250323297 -3.32228314549439 1.45186153898233e-08 727.524147547216 130.974670941343 5.5546934557525 4.86891061324484e-08 -432.569007478768 372.484227176435 -1.1613082539301 0.246157828574181 CDKN1B ts 9.84216937276122e-05 1 0.00044803715463079 5.5546934557525 -1.1613082539301 0.000240191595090203 94.8616698183486 47.4934654719092 1.99736256084442 0.0464039380720483 -155.794635864775 82.2362203844946 -1.89447709459845 0.0588201456743404 NAA25 essential 1 1 1 1.99736256084442 -1.89447709459845 1.23844468064536e-10 163.060771630338 24.1892246606443 6.74104994756763 5.01241080939177e-11 68.7563297801069 49.3681099179337 1.39272761088895 0.16441358157631 OGFOD2 other 9.08894551125628e-07 1 4.77983494783599e-07 6.74104994756763 1.39272761088895 1.23280357852623e-05 1410.98755669996 487.619152027806 2.89362620568172 0.00399915790952233 -2355.59692584701 986.216942278718 -2.38851800741149 0.0173410224672542 CDK2AP1 other 0.0679028211052245 1 1 2.89362620568172 -2.38851800741149 0.68412738444253 45.7893729217761 351.248081861791 0.130361915940066 0.896339945405909 -407.498958788161 622.23895417164 -0.654891430464438 0.512881423112562 OAS3 other 1 1 1 0.130361915940066 -0.654891430464438 0.960156876244116 56.7461279461313 198.988200275798 0.285173331220047 0.775646456057108 54.5998653198696 352.527769030343 0.154881033826218 0.876986614271947 OAS2 other 1 1 1 0.285173331220047 0.154881033826218 0.367381874772039 -16.9888888888905 59.3737380702376 -0.286134736350828 0.774910519611244 -139.082222222224 105.186595948315 -1.32224282921528 0.186778936893735 RASAL1 other 1 1 1 -0.286134736350828 -1.32224282921528 1.12738444490277e-07 164.548127851789 38.8541590667384 4.23501966852892 2.78811197504453e-05 -154.62552449957 71.5476451320712 -2.16115462939617 0.0312259276804456 GTF2H3 essential 0.000723329859849617 1 0.237798070351548 4.23501966852892 -2.16115462939617 1.31957199616279e-09 340.335369427557 53.0864830170434 6.41096094684389 3.7626917368248e-10 99.4568570213656 97.7589372503749 1.01736843524231 0.309542396725018 EIF2B1 essential 9.35312630880187e-06 1 3.56251653642572e-06 6.41096094684389 1.01736843524231 0.000798055929640147 96.2428430234562 33.6161378069641 2.8629952547231 0.00439888965335494 -82.9071460586351 61.9042309775145 -1.33928076885002 0.181177027948607 DDX55 essential 1 1 1 2.8629952547231 -1.33928076885002 0.000953434939624898 -293.329905267417 757.00373724455 -0.387488054332625 0.698585322832492 -3679.88237679233 1145.87016723215 -3.21143047617784 0.0014192289843609 SLC38A1 other 1 1 1 -0.387488054332625 -3.21143047617784 0.00258355277914213 -13.018947164163 14.5867460050416 -0.892518945600563 0.372606043465278 -71.5553722902928 22.2736442444285 -3.21255792294481 0.00141288319345166 ENDOU other 1 1 1 -0.892518945600563 -3.21255792294481 0.000872168188493799 181.797023494327 115.39318190412 1.57545723667956 0.115876232089928 -539.124535114535 226.796313707843 -2.37713094318204 0.0178784661654793 C12orf49 other 1 1 1 1.57545723667956 -2.37713094318204 0.279449769716381 -4.00077703515453 6.1105302946285 -0.654734833517058 0.51298216268306 7.12206918101608 9.33001371894973 0.763350343906868 0.445665441877968 VDR other 1 1 1 -0.654734833517058 0.763350343906868 0.000752205681715634 11.1481018624507 3.48531677165479 3.19859071436932 0.00148171043823898 -7.09493515762822 6.4715565160278 -1.09632592098308 0.273541341368486 FZD10 other 1 1 1 3.19859071436932 -1.09632592098308 6.70356922639097e-06 116.136729745547 38.2809412187247 3.03380026844116 0.00255928105284636 -161.518182015242 75.2382091420899 -2.14675739703226 0.0323636164131298 RFC5 essential 0.0379019804060145 1 1 3.03380026844116 -2.14675739703226 3.9820258912207e-11 192.239893882058 28.8613492165538 6.66080758871094 8.22595407311968e-11 -26.6162759066478 53.5899216113613 -0.496665699563274 0.619675132630121 STX2 other 2.96063625012259e-07 1 7.83028568220263e-07 6.66080758871094 -0.496665699563274 0.0757389580284416 18.6333458717323 13.830026633683 1.34731091741724 0.178578275777534 -35.3533007334961 25.6788396143844 -1.37674837587647 0.169294964338688 ADGRD1 other 1 1 1 1.34731091741724 -1.37674837587647 2.18922581253514e-08 402.463293076903 147.047804796295 2.73695546583938 0.00645457954678022 -601.710367291725 224.70620204233 -2.67776484059116 0.00769138087216239 COPZ1 essential 0.000146853267504857 1 1 2.73695546583938 -2.67776484059116 0.354796967018585 -38.8414181025204 36.0883591020009 -1.07628662175352 0.282394272298052 -81.9953172917034 58.7429199686652 -1.39583318867093 0.163475105765697 TBC1D30 other 1 1 1 -1.07628662175352 -1.39583318867093 2.09309292002928e-11 111.982956938428 205.829571433276 0.544056697774979 0.586680560486343 -1899.64373980238 335.039617836746 -5.66990779200333 2.60359811887391e-08 CAND1 other 1.56584281347391e-07 0.000238958235350247 1 0.544056697774979 -5.66990779200333 6.62985669110526e-16 43.4580857796796 282.454834244586 0.15385853067768 0.877792470737908 -3134.31316839485 454.044881582051 -6.90309107212884 1.80410076257014e-11 RAB5B other 5.40532216025812e-12 1.71822556627181e-07 1 0.15385853067768 -6.90309107212884 0.000444403264338564 28.6324183177817 46.7128476373513 0.612945255233966 0.540232122010239 -221.251627716889 76.0369586911265 -2.90979060085302 0.00380182443162792 MDM1 other 1 1 1 0.612945255233966 -2.90979060085302 3.60799865777288e-05 148.495777977934 51.2378617093959 2.89816500969835 0.00394326748378541 -110.531580725063 83.4073088276619 -1.32520257851079 0.185799592679646 NUP107 essential 0.189095209653877 1 1 2.89816500969835 -1.32520257851079 6.45205663116042e-05 135.571911237564 87.5970577523067 1.54767653978646 0.122425711346174 -369.853921963177 142.5863375636 -2.59389453634158 0.0098089960730869 CNOT2 other 0.32737735346508 1 1 1.54767653978646 -2.59389453634158 0.0235355911125579 172.120895236882 117.521330643324 1.46459280451195 0.143752708870703 -192.879655141169 189.519038255144 -1.01773234455475 0.309369574526608 TIMELESS essential 1 1 1 1.46459280451195 -1.01773234455475 4.80092584601244e-05 108.9585397433 131.389331937027 0.829279958554947 0.40740082800712 -688.463456053449 213.881497391258 -3.21890142181878 0.00138316135725686 CPSF6 essential 0.247350761155849 1 1 0.829279958554947 -3.21890142181878 0.00545725131125487 88.1065573770491 85.933182865153 1.02529144667324 0.305791595967137 -265.66994535519 139.886094143381 -1.8991876710982 0.0581965653980094 KRR1 essential 1 1 1 1.02529144667324 -1.8991876710982 3.57416022166418e-05 -21.9278471593164 72.5047253376545 -0.302433352546312 0.762465626942291 -503.711644234508 126.04676520904 -3.99622825226128 7.55275894870366e-05 UHRF1BP1L other 0.187393220421853 0.60633548840193 1 -0.302433352546312 -3.99622825226128 0.00214503302075677 351.529264268149 122.17390905303 2.87728588692015 0.00420762523122739 -31.4759123851377 212.394791613398 -0.148195311881424 0.882256986863428 CHPT1 other 1 1 1 2.87728588692015 -0.148195311881424 0.00108372788744346 67.4401190630235 107.87669698976 0.625159287824926 0.532192822062234 -513.551831241101 187.539620813283 -2.7383644534101 0.0064268776262094 GNPTAB other 1 1 1 0.625159287824926 -2.7383644534101 0.855293400807758 -63.1354155008392 206.214808457614 -0.306163344781402 0.759626420263066 -201.941850867376 361.143079566199 -0.559174084437522 0.576330021203506 NT5DC3 other 1 1 1 -0.306163344781402 -0.559174084437522 7.04210957217835e-07 86.3546769813413 36.9437237611949 2.3374654255088 0.0198676650083214 -229.137199539073 70.20643590999 -3.26376345087286 0.0011861759012132 SUDS3 other 0.00431258790200202 1 1 2.3374654255088 -3.26376345087286 3.08825474319056e-06 196.711360812491 44.8697855094502 4.38404950188721 1.46098907232298e-05 -35.5776265163597 84.2025999460695 -0.422524085231889 0.672850340264353 PRKAB1 other 0.018004525152801 1 0.126127186613643 4.38404950188721 -0.422524085231889 2.77747179153848e-06 33.2104455756216 46.7972261196155 0.709666968096237 0.478290027030315 -311.455570276366 80.6308421747648 -3.86273492717955 0.000129137959519148 HCFC2 other 0.0162593198676662 1 1 0.709666968096237 -3.86273492717955 2.24874643787698e-07 228.041029658044 50.3355797996315 4.53041428281538 7.60617732896535e-06 -94.5600813930379 94.4597046943576 -1.00106264040318 0.317350504744689 RAB35 other 0.00142098287409447 1 0.0663562910178937 4.53041428281538 -1.00106264040318 1.05273892271866e-06 528.871616876447 126.261132674576 4.18871275485509 3.39524361110548e-05 -262.688347469063 236.941530310988 -1.1086631673404 0.26818529020015 COX6A1 other 0.00637117596029336 1 0.288358039891188 4.18871275485509 -1.1086631673404 0.430424129219728 -93.6487066205627 253.176799709516 -0.369894503477456 0.7116398803866 -530.025291330511 428.911454751033 -1.23574524638931 0.217215622511124 RFX4 other 1 1 1 -0.369894503477456 -1.23574524638931 1.07006840127718e-05 60.2514406454092 34.9639132381983 1.72324648659705 0.0855497091043121 -163.020745293891 59.2330059783943 -2.75219436530629 0.00616555707925354 RIC8B other 0.0592924901147685 1 1 1.72324648659705 -2.75219436530629 6.75941681939371e-09 688.261358111399 119.664651480683 5.75158452889074 1.66362104103254e-08 68.0920833858745 224.562579515599 0.303220970888182 0.761865765962289 SRSF9 other 4.65521036351645e-05 1 0.000154317487766179 5.75158452889074 0.303220970888182 1.84176541793123e-05 23.8009769911533 103.195234867935 0.230640271535918 0.817702213688407 494.774623008852 143.384391995166 3.4506867597244 0.000613520362888247 COL12A1 other 0.099657926764259 1 1 0.230640271535918 3.4506867597244 0.0743099505130702 192.345291019582 122.772062983217 1.56668615274368 0.117915197981647 -217.647821742065 255.21350641151 -0.852806831434412 0.394235740744638 BTN3A3 other 1 1 1 1.56668615274368 -0.852806831434412 7.60430649790684e-15 166.943970464582 27.4640927505439 6.07862680849981 2.63919120281253e-09 -116.009873960025 52.8926350327574 -2.19330865040431 0.0288101259729757 TDP2 other 6.10017467262086e-11 1 2.47714486295984e-05 6.07862680849981 -2.19330865040431 0.0707970310320816 -16.7059289354083 7.37320645556288 -2.2657617192862 0.0239533542938916 -19.8040214846439 9.87408244922166 -2.00565688877805 0.0455074318557119 FRK other 1 1 1 -2.2657617192862 -2.00565688877805 0.000291695698101867 134.700351191297 93.0062082358951 1.44829419182052 0.148250245271555 -172.216094546205 124.552455427019 -1.38267924109384 0.167467775012437 DSE other 1 1 1 1.44829419182052 -1.38267924109384 5.25641239765965e-31 52.8784602671838 62.4208791247389 0.84712777212756 0.39738653728235 -642.954534499379 83.5930623596675 -7.69148200042012 9.6949680362041e-14 RWDD1 other 4.77439938079426e-27 9.36049163895506e-10 1 0.84712777212756 -7.69148200042012 0.328738925914188 -7.38718979377788 56.2841648570191 -0.131248101709315 0.895639446141746 60.4872671892948 72.9537835223705 0.829117617604398 0.407490494425379 RSPH4A other 1 1 1 -0.131248101709315 0.829117617604398 0.365370784739613 2.11160289358459 10.9350171978521 0.193104670562326 0.846967122500902 24.5529221397296 18.9302700783579 1.297019114788 0.195312116986316 MAK other 1 1 1 0.193104670562326 1.297019114788 2.26014856599242e-05 302.49390824291 86.5109876822149 3.4965952458441 0.000519678100256719 -119.397487150201 149.764406579215 -0.797235403774314 0.425749263961335 TMEM14C other 0.121053557194554 1 1 3.4965952458441 -0.797235403774314 4.01807643668494e-09 67.7417190177045 24.1403623553559 2.80615999132569 0.00523864589390903 -140.498667428136 41.7908422920519 -3.36194868833399 0.000842329099568919 PAK1IP1 essential 2.79055408527769e-05 1 1 2.80615999132569 -3.36194868833399 0.0170321225405519 -45.9264467923093 53.3272679935529 -0.861218819570161 0.389591993248721 -256.377736531505 92.3180610870206 -2.77711353025319 0.00572140377831931 GCNT2 other 1 1 1 -0.861218819570161 -2.77711353025319 0.453838979137054 113.257043594138 116.54771660435 0.971765444179541 0.331707281624984 -33.2904054825801 201.762805893862 -0.164997732535959 0.869022413707274 NEDD9 other 1 1 1 0.971765444179541 -0.164997732535959 1.23438885134483e-07 -16.0061167423957 36.4939625660591 -0.438596294206815 0.661170830809483 -185.811304738601 47.3023389736901 -3.92816314732239 9.94563061592584e-05 CEP85L other 0.000790255742630958 0.791672197027697 1 -0.438596294206815 -3.92816314732239 3.81114704927644e-05 -22.1028143950988 37.0220913351689 -0.597016905257926 0.550805985697579 234.405279936294 65.5569236021878 3.57559914432091 0.000388513952253728 ADTRP other 0.199094321854201 1 1 -0.597016905257926 3.57559914432091 4.19059646823176e-21 -91.5308283816794 71.4970371795775 -1.28020449507276 0.201152356260157 -681.47183302541 92.6722353638921 -7.35357068219519 9.59980235760429e-13 ASF1A other 3.62318970643318e-17 9.22924998660077e-09 1 -1.28020449507276 -7.35357068219519 4.97652670659451e-13 9.6039457743872 23.8586511502743 0.402535152297441 0.68748750591533 -140.706184483224 30.9275948869447 -4.54953529356464 6.97932676243092e-06 MCM9 other 3.85929646096404e-09 0.0595266779567733 1 0.402535152297441 -4.54953529356464 2.61582790747955e-08 40.5227425184473 42.7032637565977 0.948937831764359 0.343177907388793 -165.400654792298 55.3555703336236 -2.98796767507663 0.0029669873984954 FAM184A other 0.000174658829382409 1 1 0.948937831764359 -2.98796767507663 1.72396308372455e-10 59.7748859106603 37.9443103267218 1.57533199038182 0.115901816266695 -191.875417772398 53.6212344738291 -3.57834763886398 0.000384384770485572 RNGTT essential 1.25952742896916e-06 1 1 1.57533199038182 -3.57834763886398 0.328966462487943 -102.743609767818 72.3993762618554 -1.41912285813366 0.156577689135048 -76.5834109272216 93.8501747224045 -0.816017776778194 0.414935552889598 MAN1A1 other 1 1 1 -1.41912285813366 -0.816017776778194 1.72965088139501e-17 -2384.64685769779 965.85361762536 -2.46895265926597 0.0139332749586015 -9348.88958639951 1252.0208798838 -7.46703967689994 4.50540971286778e-13 SERINC1 other 1.43924249840879e-13 4.33916009446296e-09 1 -2.46895265926597 -7.46703967689994 8.31185271097574e-06 -58.9313865631988 152.464083549301 -0.386526355527811 0.699295021326903 -670.935700428834 198.40478132653 -3.38165086518063 0.000785317425568412 HDDC2 other 0.0466378055612849 1 1 -0.386526355527811 -3.38165086518063 0.0775251698956006 -228.484582397385 287.260453958312 -0.795391705502711 0.426817486801606 269.913071778644 373.818188681331 0.722043709886832 0.470653783099213 TPD52L1 other 1 1 1 -0.795391705502711 0.722043709886832 3.41473089570813e-29 -119.423524606893 84.8602032465692 -1.40729717863033 0.160050134497239 -976.007759852966 110.430402206931 -8.83821611030684 2.39865801630218e-17 HINT3 other 3.08042874101831e-25 2.34492807673701e-13 1 -1.40729717863033 -8.83821611030684 0.0154887210720316 -141.297937512766 131.982769730508 -1.07057866569461 0.284949849377852 -434.705916887895 171.752008457675 -2.53100921958079 0.0117232837730362 NCOA7 other 1 1 1 -1.07057866569461 -2.53100921958079 0.715269793229053 20.0930687740334 39.0092341019168 0.515084934032224 0.606753515495061 -23.8136592662408 75.1272288875887 -0.316977740545611 0.75141152226887 RIPOR2 other 1 1 1 0.515084934032224 -0.316977740545611 5.75192390066003e-06 -811.92514593522 456.391398587462 -1.7790106221286 0.0759330358309158 -2460.07893574341 581.268386025556 -4.23225999363958 2.82118240661247e-05 SASH1 other 0.0327284469947556 0.233565691443446 1 -1.7790106221286 -4.23225999363958 0.00136863060262236 477.719344587444 384.412525528787 1.24272575127542 0.214635306813577 -535.61690369401 489.594784156093 -1.09400042857328 0.274557436641284 UST other 1 1 1 1.24272575127542 -1.09400042857328 9.06068868568576e-09 197.495864232745 40.6843151084071 4.85434899681853 1.6830749415919e-06 68.7745769157635 53.6327095966108 1.28232523460104 0.200406835572747 FBXO5 essential 6.20022926761476e-05 1 0.0150062961792334 4.85434899681853 1.28232523460104 4.39397181501522e-19 18.6161580148322 24.4910744359867 0.760120102672098 0.447591748105598 -178.457992647523 32.2857268073519 -5.52745780549955 5.58943798717155e-08 MTRF1L other 3.72301231886239e-15 0.00050992442756966 1 0.760120102672098 -5.52745780549955 0.0002016173798861 156.627051439717 91.0541819807877 1.72015219984915 0.0861111167948234 -609.250929420581 213.774655724572 -2.84996800652338 0.00457869308648295 PPARD other 0.95909387611818 1 1 1.72015219984915 -2.84996800652338 1.13489468104254e-08 51.7925660489376 14.1824703623125 3.65187197475607 0.000291814272121577 -106.913772387374 33.2972374587586 -3.21089016828485 0.00142068854837467 FANCE other 7.72976767258076e-05 1 1 3.65187197475607 -3.21089016828485 0.205732299348134 -5.05368729061536 3.26606941765107 -1.5473300301896 0.122505887563688 -10.7870460681623 7.66799338747816 -1.40676256786783 0.160206938147295 SLC26A8 other 1 1 1 -1.5473300301896 -1.40676256786783 0.00114346118068201 137.210678088291 45.8478773455321 2.99273785467109 0.00292121041740405 -95.0489377040836 107.640461778149 -0.883022388922702 0.377708558538526 MAPK14 other 1 1 1 2.99273785467109 -0.883022388922702 1.76720618273434e-07 291.833891692462 186.032317435575 1.56872685195424 0.117433717832357 -1940.90062621037 436.761868025191 -4.44384175520201 1.12084748404966e-05 KCTD20 other 0.00112341297036422 0.0947004039273559 1 1.56872685195424 -4.44384175520201 7.40258628692224e-11 316.227556083286 46.5312718965552 6.79602218452785 3.52752451812406e-11 107.30301938001 109.244917846952 0.982224358759991 0.326531563002487 STK38 other 5.46680997289207e-07 1 3.36561114274217e-07 6.79602218452785 0.982224358759991 8.8339018523918e-09 955.489991942662 188.304321098943 5.07417985082035 5.76123251302666e-07 -614.498480415027 442.096019520219 -1.38996610076224 0.165245169209239 SRSF3 essential 6.04945598851791e-05 1 0.00519836009650395 5.07417985082035 -1.38996610076224 2.29797111670914e-29 78.2257561305413 53.8801095342953 1.45184849857719 0.147259634910354 -470.747992750002 70.7756116909572 -6.65127409714989 8.68351809751605e-11 MRPL18 essential 2.07483812127669e-25 8.21721317567943e-07 1 1.45184849857719 -6.65127409714989 0.0012090488323842 453.955005832152 128.522110523485 3.53211602255163 0.000456010375819745 153.771984124235 295.128738823437 0.521033582623177 0.602606690514062 MCM3 essential 1 1 1 3.53211602255163 0.521033582623177 1.86202442039541e-08 67.1954963741993 22.5263799901028 2.98296914123451 0.00301413289147872 -199.290982853427 52.886852886353 -3.76825188070233 0.000186890281369864 RNF8 essential 0.000125481825690447 1 1 2.98296914123451 -3.76825188070233 0.00229129465637917 -278.097809666647 171.403283959598 -1.62247655495444 0.105427498702206 -1063.95734742929 303.544087113691 -3.50511636561969 0.000503882699535489 PHACTR1 other 1 1 1 -1.62247655495444 -3.50511636561969 0.0364167078269565 28.5816759255343 90.0281463005727 0.317474890909227 0.75103457510353 -475.316073675134 211.365755666085 -2.24878468216033 0.025022466275217 MDGA1 other 1 1 1 0.317474890909227 -2.24878468216033 0.00366024729550048 -64.3572674347214 103.534770315385 -0.621600523560133 0.534530195394405 -756.470358724938 232.238772043982 -3.25729572227361 0.00121287274662722 ICK other 1 1 1 -0.621600523560133 -3.25729572227361 0.00749142605055705 26.6497334741695 58.5757353655091 0.454961995916513 0.64936355279565 -343.164283901187 131.391191687781 -2.61177541274329 0.00931885471210539 FBXO9 other 1 1 1 0.454961995916513 -2.61177541274329 0.126734575715695 169.584032707063 85.3791554754612 1.98624631226064 0.04763311388322 216.873742924939 159.925994260138 1.35608813269073 0.175774620880232 CD83 other 1 1 1 1.98624631226064 1.35608813269073 1.42150346212246e-10 -83.9455819081942 170.583005218141 -0.492109878125578 0.622888786425393 -1234.11242784251 239.492973885047 -5.15302143450298 3.88866273107336e-07 MDN1 essential 1.0412512860047e-06 0.00347957541176444 1 -0.492109878125578 -5.15302143450298 0.0973120824509421 -25.9170942708111 17.6661958050281 -1.46704443655236 0.143081602295096 -84.232220855774 41.4762380379148 -2.03085489042604 0.042873208736961 GLP1R other 1 1 1 -1.46704443655236 -2.03085489042604 2.54072377212574e-16 142.335842415503 23.0427703398246 6.17702820955975 1.49341797589255e-09 -188.215894152072 54.0992208065277 -3.47908696920385 0.000553491545223702 SAYSD1 other 2.08390163789753e-12 1 1.40500763171971e-05 6.17702820955975 -3.47908696920385 1.10477526366001e-08 71.6982466002213 34.2842713501132 2.09128687228129 0.0370792332320433 -122.668740406027 48.1339984169029 -2.54848432377374 0.0111602584777573 BACH2 other 7.52793864657931e-05 1 1 2.09128687228129 -2.54848432377374 0.848273380503775 -7.02842315749386 12.6603380724574 -0.55515288116865 0.579074146731826 -3.18901161683495 24.3139707140037 -0.131159638807915 0.895709383019021 RBM24 other 1 1 1 -0.55515288116865 -0.131159638807915 0.758725154815863 -91.0896019805802 162.761960611227 -0.559649205738906 0.576005464706118 -216.949279502321 312.581664170921 -0.694056319898829 0.488015670060177 CAP2 other 1 1 1 -0.559649205738906 -0.694056319898829 7.40380563013716e-13 149.802483355338 42.1799107529862 3.55151257271764 0.00042485456356061 -402.039848863668 89.6500243175286 -4.48454812950966 9.36075374399882e-06 ZNF451 other 5.71943984928096e-09 0.079388552502854 1 3.55151257271764 -4.48454812950966 7.37849052296834e-07 120.044176159106 46.1618677522409 2.60050517893697 0.00962635857629186 -252.47713809645 89.4831709566926 -2.821504148737 0.00499932283066311 BAG2 other 0.00451416050195203 1 1 2.60050517893697 -2.821504148737 0.000200600864475106 179.853020878424 68.3752110819543 2.6303834099006 0.00883217784802675 -199.116399731976 132.542962414025 -1.50227817535869 0.133752513426473 RAB23 other 0.954458913172554 1 1 2.6303834099006 -1.50227817535869 0.134235572897635 -11.4164706521445 21.947173671553 -0.52017953760224 0.603203072560361 -53.1301518320338 30.8180197032497 -1.72399629644053 0.0854189822639756 FHL5 other 1 1 1 -0.52017953760224 -1.72399629644053 0.00162999399887073 34.8422270052909 11.4100462291755 3.05364468341937 0.00239990380598841 15.0010399498302 15.4447234024775 0.971272813304239 0.331953436085756 GPR63 other 1 1 1 3.05364468341937 0.971272813304239 0.0447344676580988 -24.6433405529513 25.3717432390637 -0.971290790733253 0.331954650398535 -89.1887124670848 37.6177358507838 -2.3709218657089 0.0181878724564448 KHDRBS2 other 1 1 1 -0.971290790733253 -2.3709218657089 6.30362776399984e-08 37.5412280784268 30.7391679413399 1.22128315737327 0.222638801518735 -122.673361114508 41.6024327242004 -2.94870643569716 0.00336263421862066 FBXL4 other 0.000410744385102229 1 1 1.22128315737327 -2.94870643569716 4.78192413238282e-21 65.7986956521789 38.7696162437335 1.69717170370017 0.0903762183087073 -283.729565217388 52.165502477346 -5.43902678481059 8.93436147409524e-08 CCNC other 4.13110425796552e-17 0.000812044114380516 1 1.69717170370017 -5.43902678481059 0.0242324109935666 125.635330306622 69.0292157749295 1.82003125627643 0.0694381950891362 -123.554826292931 130.576549356471 -0.946225236475113 0.344556619308292 E2F3 other 1 1 1 1.82003125627643 -0.946225236475113 1.39778834227653e-11 -67.9330815531717 227.141258319567 -0.299078564835614 0.765025268154498 -1821.86875958929 329.195534205112 -5.53430581611152 5.45514155189164e-08 PTP4A1 other 1.05057771805504e-07 0.000497781666610112 1 -0.299078564835614 -5.53430581611152 3.4131447593176e-07 -128.385379995848 133.975543237493 -0.958274748461104 0.338454089073357 -776.277800786906 179.28274791342 -4.32990797955524 1.85158612574998e-05 ASCC3 other 0.00213150890219384 0.154607441500123 1 -0.958274748461104 -4.32990797955524 0.0458119443481318 135.366353605483 54.8217594348003 2.4692084858472 0.0139225787153974 120.101178300825 72.9795621290095 1.64568236362553 0.10054817218933 BVES other 1 1 1 2.4692084858472 1.64568236362553 0.440940110998831 -26.2650800196653 147.440869357706 -0.178139752797737 0.858696341944939 -216.727076625372 209.905063298139 -1.03250047054627 0.302412738252374 COL9A1 other 1 1 1 -0.178139752797737 -1.03250047054627 7.13106472757956e-13 60.007529654467 59.4491958942635 1.00939177985177 0.31334534167349 -297.237324769089 76.2168469502887 -3.89989007237412 0.00011137281393155 MED23 other 5.51017371500073e-09 0.881181703826423 1 1.00939177985177 -3.89989007237412 1.19339891307942e-06 -122.010607479705 265.891928066906 -0.45887292768438 0.646553042858621 -1424.55208991311 364.649778843258 -3.90663088959515 0.00010837919307967 WASF1 other 0.00718187465891197 0.859121863542541 1 -0.45887292768438 -3.90663088959515 0.00236091321592477 -5.36146635663409 11.3188020110815 -0.473677899073155 0.635965625896693 -73.1125199825601 22.1733435256442 -3.29731598204859 0.00105565340761355 GPLD1 other 1 1 1 -0.473677899073155 -3.29731598204859 2.50766198613262e-10 -680.305079203603 234.398453688956 -2.90234456967178 0.00389072683490479 -3129.43434820518 459.182644102846 -6.81522785844723 3.12660418483578e-11 ALDH5A1 other 1.82206719912396e-06 2.97121195684945e-07 1 -2.90234456967178 -6.81522785844723 0.981476908454586 7.67297110426168 46.6790216309358 0.164377290615203 0.869510141863607 11.864308144393 62.139825397026 0.190929215983294 0.84866972028662 CRYBG1 other 1 1 1 0.164377290615203 0.190929215983294 0.107981820542113 -2.34718211073525 6.93799729085079 -0.338308306033861 0.735292968089617 8.89825893225511 8.86415224971642 1.00384770946819 0.316006272756652 VNN1 other 1 1 1 -0.338308306033861 1.00384770946819 0.537291470497881 7.60227741562825 10.6069142111272 0.716728472042609 0.473923651477239 14.7586709574497 13.5516487720598 1.08906829019052 0.276722614960875 VNN2 other 1 1 1 0.716728472042609 1.08906829019052 1.6052794441829e-07 219.140725545845 49.1207163743302 4.46126892523019 1.03709674329491e-05 -95.1743052238182 94.6007627972195 -1.00606276746233 0.314940842559749 ACOT13 other 0.00102288406183334 1 0.0900041099685746 4.46126892523019 -1.00606276746233 0.014086067438512 -43.0065189461763 243.482056558597 -0.176631163519954 0.859880508266069 -769.575023395239 346.634665927667 -2.22013289217826 0.0269256423547432 SMAP1 other 1 1 1 -0.176631163519954 -2.22013289217826 3.54737825852965e-08 2980.06531066919 1200.31406287436 2.482737979036 0.013411206451378 -2057.51009434225 1533.55012329348 -1.34166471841396 0.180399892305566 RPS12 essential 0.000234765493149492 1 1 2.482737979036 -1.34166471841396 0.000151420741902061 837.131030994467 330.117605444256 2.53585697093585 0.0115638172561395 -1137.32863124175 635.767952768258 -1.78890525432997 0.0743209894351372 C6orf62 other 0.734390598224998 1 1 2.53585697093585 -1.78890525432997 0.975860566615372 48.7526686440386 565.815639844374 0.0861635225520594 0.931376163962255 -68.9498231478006 805.526772963258 -0.0855959422604388 0.931827096926443 B3GAT2 other 1 1 1 0.0861635225520594 -0.0855959422604388 0.123752690100472 191.264022514703 116.462478276824 1.64228020341522 0.101249662326932 -67.7301780468676 224.293131197079 -0.301971699647615 0.762816966853897 GMNN other 1 1 1 1.64228020341522 -0.301971699647615 0.00666836527043613 -5.21668454493063 58.8967197163909 -0.0885734310849715 0.929461407186965 140.615823637813 75.2478660179678 1.86870181280937 0.0623315809408617 EYA4 other 1 1 1 -0.0885734310849715 1.86870181280937 1.37780210920039e-22 -214.314269669226 98.498524606753 -2.17581197814747 0.03010443623101 -1098.77682652889 130.472690558807 -8.42150814720605 5.39069634065965e-16 SOBP other 1.20364792259746e-18 5.25269451433876e-12 1 -2.17581197814747 -8.42150814720605 0.5136429068639 -96.2309878137799 89.7352527458002 -1.07238777257786 0.284137745812523 -63.7199247486937 118.864723207402 -0.536070947117857 0.592182267566337 NR2E1 other 1 1 1 -1.07238777257786 -0.536070947117857 1.32639377470297e-17 -66.471679676525 252.012443524671 -0.263763482258438 0.792086507729298 -2066.64516482282 333.819635291359 -6.19090354891509 1.37988333898431e-09 SNX3 other 1.10528393245998e-13 1.29032891028423e-05 1 -0.263763482258438 -6.19090354891509 2.03864840904833e-15 -27.7124285415612 71.6755427184318 -0.386637163675564 0.699212605188644 -500.179208657516 91.2785761643308 -5.47969994357748 7.2018564266119e-08 HBS1L other 1.65028588712462e-11 0.000655657009078748 1 -0.386637163675564 -5.47969994357748 0.479725877122449 19.1648545654185 28.9318764707439 0.662413120172074 0.508054890601421 69.5789537896237 57.7229881543323 1.20539417681552 0.228701974680685 TRIM38 other 1 1 1 0.662413120172074 1.20539417681552 7.3331057339685e-25 -0.344213302080793 13.614093218605 -0.0252836010855569 0.979840295406392 -118.41980662174 17.3391567344876 -6.82961740499198 2.86329140916671e-11 PEX7 other 6.48613202169514e-21 2.7221311426948e-07 1 -0.0252836010855569 -6.82961740499198 4.27541981544957e-15 25.4277841911512 23.6100562221045 1.07698956546088 0.282077747363273 -157.517815870805 32.3793273547624 -4.86476492068439 1.60113493664075e-06 ZBTB24 other 3.44470574530772e-11 0.0140259420449729 1 1.07698956546088 -4.86476492068439 7.97053169776257e-07 39.9106096578147 43.882910803388 0.909479542882405 0.363597233779845 -175.290438747433 60.181946235793 -2.91267480883129 0.00376671109696891 FIG4 other 0.0048644154951445 1 1 0.909479542882405 -2.91267480883129 0.0261832564691538 -31.271504879532 32.0191980556645 -0.976648597668415 0.329283479211542 -94.1133651874043 40.7802330045054 -2.30781823088178 0.0214755443211317 PERP other 1 1 1 -0.976648597668415 -2.30781823088178 9.74988470851308e-08 -802.041808469863 400.877058896505 -2.00071765313197 0.0460409290301455 -2491.84375352158 510.564313307909 -4.88056781206878 1.48523042538728e-06 ARFGEF3 other 0.000629452556781604 0.0130225003697957 1 -2.00071765313197 -4.88056781206878 0.907371590957102 -2.90531680860755 54.2785103690281 -0.0535260969554049 0.957337142441166 19.0569047843779 74.4386899816951 0.256008062327052 0.798064801530877 SLC16A10 other 1 1 1 -0.0535260969554049 0.256008062327052 1.96009836033038e-16 65.1706474553498 65.2313289407769 0.999069749361043 0.318312519570843 -372.814229371076 82.8137124099398 -4.50184176656146 8.64714227160571e-06 HECA other 1.60982878333934e-12 0.0734488264550189 1 0.999069749361043 -4.50184176656146 0.0365358782819367 45.7611937987943 40.148935777652 1.13978597221664 0.254999814782264 117.466337881771 50.9755607317393 2.30436578226068 0.0216702421807377 ADGRG6 other 1 1 1 1.13978597221664 2.30436578226068 0.167765945314781 -134.795205343127 71.4475544500955 -1.88663147928007 0.059872604808235 -127.996479200303 90.7142139750656 -1.41098592592651 0.158960256073848 PHACTR2 other 1 1 1 -1.88663147928007 -1.41098592592651 1.06942446384582e-09 -34.5459900890542 37.6338886608689 -0.917948990080703 0.359153078061409 -224.165087528613 47.9357951966577 -4.67636109110051 3.90026536527141e-06 EPM2A other 7.60681621133529e-06 0.0336319882447354 1 -0.917948990080703 -4.67636109110051 3.56728677207008e-07 798.852234765596 147.652537873027 5.41035221116594 1.03841958831591e-07 331.163057251475 344.160988302048 0.962232991267548 0.33646470559687 SLC39A7 essential 0.00222491675974011 1 0.000949738555473734 5.41035221116594 0.962232991267548 0.000324911026318617 229.133266263304 123.088914214393 1.86152642360794 0.063341035191734 -753.83147237612 288.990813864801 -2.60849631271943 0.0094057510704779 PHF1 other 1 1 1 1.86152642360794 -2.60849631271943 1.80983743811953e-07 824.365918977519 173.854669950987 4.74169557372216 2.87320547694726e-06 -435.723385714081 408.179752693415 -1.06747917514016 0.286344861301694 CUTA other 0.00114978972443734 1 0.0254537273202758 4.74169557372216 -1.06747917514016 0.0624033936495642 -11.6398317170562 39.0606194109591 -0.297994038307299 0.76584901503282 -88.5191417886788 51.4922483504903 -1.71907703827883 0.0863068850021511 PACRG other 1 1 1 -0.297994038307299 -1.71907703827883 3.20315182654014e-09 -230.43938961775 1875.99738003841 -0.122835667080213 0.902293571887396 -10281.011519934 2473.06172955119 -4.15719971607816 3.87676735938972e-05 QKI other 2.2345187141944e-05 0.317856155796363 1 -0.122835667080213 -4.15719971607816 0.99065626115116 1.60303764974343 19.0621898031275 0.0840951467958011 0.933019204996541 -0.0945838879380022 25.1290180813527 -0.00376393091173703 0.99699853839541 C6orf118 other 1 1 1 0.0840951467958011 -0.00376393091173703 5.9081774079162e-05 66.1811180832863 39.0121898449648 1.69642151200154 0.0905165950035143 -67.4393262343911 51.4284053475556 -1.31132446706509 0.190435166454249 PDE10A other 0.301257966029647 1 1 1.69642151200154 -1.31132446706509 0.00116198770310643 248.831372549018 176.022772261556 1.41363170998849 0.158180384758281 -1075.14258421317 410.279949104122 -2.62050969480919 0.00908504498471431 MDFI other 1 1 1 1.41363170998849 -2.62050969480919 0.013953768464166 179.39299719888 68.5207612399166 2.61808237317678 0.00914890189251331 -36.0618544853839 159.710553770369 -0.225795062593255 0.82146613873271 TFEB other 1 1 1 2.61808237317678 -0.225795062593255 0.135775057203947 0.288594210269175 35.8521786212758 0.00804955853081448 0.993581132640118 -56.7580671470651 46.1297678134154 -1.23040001798055 0.219210756206064 SMOC2 other 1 1 1 0.00804955853081448 -1.23040001798055 0.937960356944116 -27.742016806726 156.644341473262 -0.177101940266775 0.85951018394344 -129.681383322562 365.112034206582 -0.355182440382634 0.722623890360443 CCND3 other 1 1 1 -0.177101940266775 -0.355182440382634 9.90867282525383e-13 182.226050420169 29.72586492553 6.13021861186164 1.95979546497551e-09 -132.69943977591 69.286071296504 -1.91523977753095 0.0561128569542386 BYSL essential 7.63066894272798e-09 1 1.84259969616997e-05 6.13021861186164 -1.91523977753095 1.10096953013276e-22 -116.904688927524 105.737647762616 -1.10561083399528 0.269506096910376 -1019.23692198874 136.558413584118 -7.46374313554028 4.62319893844879e-13 FAM120B other 9.62137272383019e-19 4.45167825783234e-09 1 -1.10561083399528 -7.46374313554028 1.43466770485496e-26 5.18914856620898 22.4544575114406 0.231096590223349 0.817348419849424 -205.651380743272 28.9995584405127 -7.09153489923401 5.40311512731816e-12 TBP essential 1.27986705950111e-22 5.16699899625435e-08 1 0.231096590223349 -7.09153489923401 0.000384064173413258 0.72156862745097 3.46623083672595 0.208170967670616 0.835192239957935 -29.1743086978381 8.07921039422044 -3.61103465243438 0.00034026509175259 GUCA1B other 1 1 1 0.208170967670616 -3.61103465243438 0.331074938599635 -9.81693999185582 6.59454116794278 -1.48864640341889 0.137300130301173 -9.08184947987998 16.4167763977816 -0.553205407677186 0.580405012576521 PRPH2 other 1 1 1 -1.48864640341889 -0.553205407677186 0.000128225513781745 5.44267574871386 33.7785035367619 0.161128385773232 0.872066576267837 -330.441238169275 84.0898745632802 -3.92961982504336 9.88431343456819e-05 BICRAL other 0.626638085851386 0.787186721929011 1 0.161128385773232 -3.92961982504336 4.04698227319039e-11 350.892337188445 68.2011625372804 5.14496123136667 4.04940167387742e-07 -463.211775620019 169.786990844432 -2.72819356368968 0.00662495077482904 PPP2R5D other 3.00812192366242e-07 1 0.00366673321569601 5.14496123136667 -2.72819356368968 1.64017245047707e-05 105.910037726514 25.7768756993081 4.10872283212184 4.75138447098464e-05 -48.2379646236626 64.1716063998786 -0.751702619427552 0.452634560662082 MRPL2 essential 0.0892417830304576 1 0.401016849351104 4.10872283212184 -0.751702619427552 0.299595810360799 107.337831653168 78.8317965507791 1.36160580311051 0.174023883101511 233.636950337071 196.251984882236 1.19049471258733 0.234498296630907 PTK7 other 1 1 1 1.36160580311051 1.19049471258733 0.000722334601826815 149.399987630651 62.4779598187434 2.39124305697689 0.0172135618855825 -301.153126352899 155.539061169599 -1.9361896882258 0.0534889574964664 SRF essential 1 1 1 2.39124305697689 -1.9361896882258 1.98355980122007e-14 335.322716308988 55.1348117927204 6.08186924750257 2.59481981029709e-09 -411.183452903706 137.258272979483 -2.99569158184854 0.00289399559980547 CUL9 other 1.58050044961215e-10 1 2.43575735592588e-05 6.08186924750257 -2.99569158184854 0.00473107368306881 56.6626254025857 63.547486887288 0.891658005344668 0.373065833819164 -416.962635274373 158.198251599514 -2.63569686174492 0.00869449373854306 DNPH1 other 1 1 1 0.891658005344668 -2.63569686174492 0.00160024796256913 91.9322255034529 42.9102252134421 2.14243167091684 0.0327183688645042 -101.59041800265 73.5070837568168 -1.38204935919838 0.1676723858151 DUSP22 other 1 1 1 2.14243167091684 -1.38204935919838 3.96235629131867e-12 82.1143322946958 51.4981411850454 1.59451060572534 0.111554723488973 -478.176815618455 88.2185576649844 -5.42036537747944 9.92022895418739e-08 EXOC2 other 3.01614560895177e-08 0.000900161575302964 1 1.59451060572534 -5.42036537747944 3.24803843397906e-09 196.523454867254 158.175261745747 1.24244115481945 0.21474013252888 -762.737854867258 219.776269351147 -3.47051962033533 0.000571080955774641 COX7A2 other 2.2645323961702e-05 1 1 1.24244115481945 -3.47051962033533 3.347970655845e-18 -101.783674336275 508.37834282702 -0.200212451557772 0.841407567196499 -4719.0791256637 706.365169700409 -6.68079249669857 7.25237190135587e-11 TMEM30A other 2.80928217731954e-14 6.87017190215442e-07 1 -0.200212451557772 -6.68079249669857 0.000881217244367014 53.4824757475355 18.2513813688227 2.93032481579148 0.00356562622134523 -16.5074668946243 31.2634465450868 -0.528011742749411 0.597762293169754 GMDS other 1 1 1 2.93032481579148 -0.528011742749411 5.78318846345125e-20 -27.8799716814118 107.704193661859 -0.258856881366589 0.795867551454509 -1059.04522831858 149.64935486894 -7.07684459612986 5.90693447234788e-12 SENP6 essential 4.93768631009468e-16 5.64525727522287e-08 1 -0.258856881366589 -7.07684459612986 0.832844572230762 -286.092876967648 792.038123276007 -0.361210992956145 0.718116687201318 -951.517584732888 1600.68320742123 -0.594444659831114 0.552523077545043 VEGFA other 1 1 1 -0.361210992956145 -0.594444659831114 9.88216722045189e-07 291.302120141341 95.0298460572492 3.06537506086089 0.0023090372243136 -356.297907039958 163.97029476483 -2.1729417974821 0.0303225023963342 PRPF4B other 0.00599071882980619 1 1 3.06537506086089 -2.1729417974821 0.00447168485310295 116.996417699117 37.3025227266595 3.13642105539156 0.00182576494845263 78.6763823008866 51.8299081143897 1.51797263709683 0.129744376979314 TTK essential 1 1 1 3.13642105539156 1.51797263709683 0.692236529376324 -20.049563420514 65.6803615641961 -0.305259638391569 0.760314089404303 77.9602418913721 132.737867942913 0.587324801125332 0.557289609584797 SLC29A1 other 1 1 1 -0.305259638391569 0.587324801125332 0.00119163439156658 7.93449728055614 4.62241331224801 1.71652700539177 0.0867726441289284 -5.80903459737106 6.30647985781408 -0.921121565174484 0.357494021485864 WISP3 other 1 1 1 1.71652700539177 -0.921121565174484 1.83620665174409e-07 135.869218095881 33.0041748176467 4.11672822746154 4.59904225751099e-05 -123.969471978393 68.6077188633823 -1.80693184429075 0.0714637279451319 BTN2A1 other 0.00116562398252715 1 0.388251147379078 4.11672822746154 -1.80693184429075 0.320811250538793 -138.812521458609 269.715901112108 -0.514661986505985 0.607048840426671 -486.522366495763 366.160515973373 -1.32871335185452 0.184634361309317 LAMA4 other 1 1 1 -0.514661986505985 -1.32871335185452 0.805362858630645 49.4527343763872 83.6171031062804 0.591418890864121 0.554546284888697 26.0372319473678 116.189589715686 0.224092640408495 0.822790189244589 FAM46A other 1 1 1 0.591418890864121 0.224092640408495 0.0788015949024126 -18.5572990617276 11.627972151253 -1.59591877417147 0.111229806956543 -56.303043166416 26.904091879167 -2.09273159708519 0.0369493076210226 CLIC5 other 1 1 1 -1.59591877417147 -2.09273159708519 3.00134022587371e-05 339.46139293393 76.603876709882 4.4313866022676 1.18463349422837e-05 29.1494146034621 138.484611836379 0.210488473895587 0.833384330879003 FBRSL1 other 0.158950978362272 1 0.102648492274888 4.4313866022676 0.210488473895587 5.66852125530012e-05 -105.259013129974 93.909719164504 -1.12085324145831 0.262965907426168 774.167780347494 217.282573425869 3.56295384457796 0.000407066843103103 ENPP5 other 0.289888176996048 1 1 -1.12085324145831 3.56295384457796 0.0859423811837452 121.378562902145 57.7988113320857 2.10001832398869 0.0363012341024969 175.813739191197 103.287593991121 1.70217673195398 0.0894350535843043 LY86 other 1 1 1 2.10001832398869 1.70217673195398 0.907533617427989 4.01410240558333 14.7351346041346 0.272417084297078 0.785430302575713 8.86388740056879 20.3294040378313 0.436013145494765 0.663042992210707 TBX18 other 1 1 1 0.272417084297078 0.436013145494765 0.0787442101169589 210.814060311445 108.207740228348 1.94823457052675 0.0520281481550868 -80.3864834802669 228.141327208029 -0.352353887233097 0.724743135227817 PCDHB2 other 1 1 1 1.94823457052675 -0.352353887233097 0.000901359681157254 100.544751399986 31.9472433361485 3.14721211911949 0.00176141691011258 -61.6319723230405 69.775026030847 -0.883295583376687 0.377563358835368 HARS2 essential 1 1 1 3.14721211911949 -0.883295583376687 0.0572751603472879 -22.5639421889943 46.937461043475 -0.48072353483489 0.6309541297865 -151.173667251193 70.9808418501862 -2.12978126647559 0.0337491365471708 CEP72 other 1 1 1 -0.48072353483489 -2.12978126647559 0.0704226960248345 -779.719812380265 774.286802405097 -1.00701679269011 0.314485241521577 -2868.57320473013 1269.39380127234 -2.25979770962715 0.0243265704219244 SEMA5A other 1 1 1 -1.00701679269011 -2.25979770962715 0.344220119459297 5.01941804874939 81.9147218896818 0.0612761410031919 0.951167564672821 226.723996143932 174.263763982342 1.30103924627099 0.193936918749779 C7 other 1 1 1 0.0612761410031919 1.30103924627099 2.17326738433985e-06 65.2008720354093 45.1905068141988 1.44280019481709 0.149794776510043 -225.55996564709 74.0869520804346 -3.0445302352593 0.00247157745727567 PAPD7 other 0.0128396637066799 1 1 1.44280019481709 -3.0445302352593 0.378400438375274 -5.8349170748987 21.8149961711652 -0.267472752647613 0.789233135333876 -66.5602313639858 49.7063449729308 -1.33906911482293 0.18125394973176 GHR other 1 1 1 -0.267472752647613 -1.33906911482293 0.134654062660013 -455.111314407128 626.571300606553 -0.726351995322092 0.468017283146771 -2848.77626158297 1427.66787459966 -1.99540545267351 0.0466277007147775 HMGCS1 essential 1 1 1 -0.726351995322092 -1.99540545267351 0.0268330188405824 171.854495840853 192.998007821032 0.890446993630183 0.373716999168875 -477.213899036131 320.196919614407 -1.49037629597065 0.1368483817271 DAP other 1 1 1 0.890446993630183 -1.49037629597065 0.0113614129402812 73.5219264593038 121.851987267709 0.603370762413384 0.546579457606146 -649.082883786816 277.644647161192 -2.33781882857614 0.0198533434623803 NNT other 1 1 1 0.603370762413384 -2.33781882857614 4.55785869354838e-07 22.965115000795 51.3237501030617 0.447455904034281 0.654768648222661 -539.16989336623 108.500384884264 -4.96929014529632 9.67909900710492e-07 PFDN1 essential 0.00282769553347742 0.00853696532426654 1 0.447455904034281 -4.96929014529632 0.841396579080983 -38.9442401885944 90.6511743380385 -0.429605468136257 0.667695372362244 -100.951483467491 191.640074743894 -0.526776477218567 0.598617329683623 HBEGF other 1 1 1 -0.429605468136257 -0.526776477218567 0.668712425806722 -5.66494845360837 14.251275958588 -0.397504649413135 0.691193065411624 -25.8759539429643 28.937582939249 -0.894198869245154 0.371716878935568 CDH9 other 1 1 1 -0.397504649413135 -0.894198869245154 2.64650767877876e-06 31.8227613645369 14.320266944964 2.22221844654425 0.0267809834476893 -107.751963394646 30.2730499745605 -3.5593362243049 0.000412650023941404 TMCO6 other 0.0155402930897889 1 1 2.22221844654425 -3.5593362243049 0.0522011774549719 17065.8660482365 19988.9460254833 0.853765177337505 0.393701789193687 -60918.3877551031 37960.8840752246 -1.60476736090722 0.109265761515929 SPARC other 1 1 1 0.853765177337505 -1.60476736090722 0.00399336807783541 102.937045555722 82.2142455950177 1.25205850653648 0.211216720686189 -354.997440273038 161.716881426682 -2.19517861797245 0.0286748074827887 FAF2 essential 1 1 1 1.25205850653648 -2.19517861797245 0.483510119697449 9.55310208453494 54.1906085854374 0.176287041867659 0.860150293677267 -119.458474087502 114.25353989283 -1.04555599939883 0.296345382026628 PCDHB3 other 1 1 1 0.176287041867659 -1.04555599939883 0.134044906830299 -299.118896925868 149.299476053566 -2.00348256291636 0.0457424293057621 -186.355416735173 314.770940825194 -0.592035008843666 0.554133315521958 PCDHB5 other 1 1 1 -2.00348256291636 -0.592035008843666 0.0228842476321513 113.953548824594 46.3532387033028 2.45837296405513 0.0143437766820731 -25.9590251520624 97.7274196976989 -0.265626834642331 0.790651881224645 PCDHB6 other 1 1 1 2.45837296405513 -0.265626834642331 0.276184785876552 98.6171451175425 69.536670775862 1.41820343161691 0.156844084483327 -26.6086429393376 146.605492936337 -0.181498267264054 0.856060645426182 PCDHB7 other 1 1 1 1.41820343161691 -0.181498267264054 8.48337357004209e-05 163.611547288321 59.8107305074671 2.73548819584965 0.00648175785405054 -197.732886994633 114.702864358059 -1.72387052495381 0.0854368480576668 CLK4 other 0.423574842352201 1 1 2.73548819584965 -1.72387052495381 0.433875090033751 32.5295547016301 91.5655848464851 0.355259618077771 0.722566508516755 -198.17526302811 193.049473790493 -1.02655168717621 0.305199491310128 PCDHB15 other 1 1 1 0.355259618077771 -1.02655168717621 0.130991912323202 5.97953782820797 3.27690572637428 1.82475125240298 0.0687211493426091 0.591828968762093 6.28454512040423 0.0941721250183379 0.925015589645838 GRM6 other 1 1 1 1.82475125240298 0.0941721250183379 0.903934092585747 -23.3825209675456 83.2285332218839 -0.280943566615655 0.778886649996923 24.7675337304002 152.726850890566 0.162168823530232 0.87124786528154 ITK other 1 1 1 -0.280943566615655 0.162168823530232 0.0845165160786888 95.3794399321149 179.054538771116 0.532683731932859 0.594524527354876 -622.097910857884 362.253230676323 -1.71730120859497 0.0866358972198046 RNF130 other 1 1 1 0.532683731932859 -1.71730120859497 0.000427051035130331 34.5570074146116 17.7560990342957 1.94620492642359 0.0522707064357039 -65.7493162756765 32.5829734663156 -2.01790411619886 0.0442118725287728 THG1L essential 1 1 1 1.94620492642359 -2.01790411619886 2.20800303230736e-06 136.949130910419 73.3321971693288 1.86751708249236 0.0624986040815093 -435.901862768929 134.566777870511 -3.23929776477507 0.00128969268212135 CLINT1 other 0.0130404659088073 1 1 1.86751708249236 -3.23929776477507 0.00182748527456704 183.391744453874 87.9814141617939 2.08443733487421 0.0377032156517296 -304.421586454925 177.99912662545 -1.71024202324035 0.0879341661493071 CNOT6 other 1 1 1 2.08443733487421 -1.71024202324035 1.69110187665773e-09 104.711173218392 56.8736654964103 1.84111877271215 0.0662833548857001 -466.458016662354 104.369177860954 -4.46930814463053 1.00159879175592e-05 TTC1 essential 1.19239593323136e-05 0.0848554496375618 1 1.84111877271215 -4.46930814463053 0.100597735381023 -25.7804360438499 211.743675824046 -0.121753039109762 0.903150829761982 -744.502748175517 388.588068382968 -1.91591767414171 0.0560307400972539 GABRG2 other 1 1 1 -0.121753039109762 -1.91591767414171 0.00118911778042913 90.8045646548834 92.2825907294158 0.983983695485249 0.325670493992227 -416.911736736188 164.566108165101 -2.53339974667154 0.0116464126641633 CCNG1 other 1 1 1 0.983983695485249 -2.53339974667154 1.05411157935524e-05 62.6385644510487 108.601201602361 0.576775979702298 0.564391211923838 -918.02854599213 234.342566300829 -3.91746390970919 0.000103990915284951 DROSHA other 0.0584399459594543 0.826207821938934 1 0.576775979702298 -3.91746390970919 0.1745773244269 -50.3461456784888 82.2729563111477 -0.61194039859325 0.540899114628473 -327.060873613541 177.530777142811 -1.84227703431075 0.0661197659046949 CDH6 other 1 1 1 -0.61194039859325 -1.84227703431075 0.000799659456922991 527.289194647826 156.861376877211 3.36149793623565 0.000843348554699444 988.613228982595 331.978483249584 2.97794368871595 0.00306335689972553 LMNB1 other 1 1 1 3.36149793623565 2.97794368871595 6.88463180835055e-06 129.040152155537 74.4509120789732 1.73322459795602 0.0837660235637427 -512.068786982249 160.642579228466 -3.18762802142254 0.00153818146900525 GOLPH3 other 0.0388637465581389 1 1 1.73322459795602 -3.18762802142254 1.07953445877022e-05 815.352071005926 325.209438955182 2.50715992015931 0.0125349501145669 -1675.88979289939 701.703734774759 -2.3883153385771 0.0173524274422692 SUB1 other 0.0597738229821071 1 1 2.50715992015931 -2.3883153385771 0.881449505167569 -9.61411665257805 36.2258185543058 -0.265394048671822 0.790831933101958 18.9171597633138 78.1643738770213 0.242017671542751 0.808880786602808 NPR3 other 1 1 1 -0.265394048671822 0.242017671542751 1.21579126788972e-07 210.617497886732 91.4305549537007 2.30357890743839 0.021718081950479 -683.343195266267 197.279519591011 -3.46383241749034 0.000585448135054361 TARS essential 0.000778714307083365 1 1 2.30357890743839 -3.46383241749034 1.11534402418886e-05 87.9918231026147 33.4009323448041 2.63441218329652 0.00872901250413428 -151.464346778409 69.6272887635194 -2.1753589643974 0.0301410376139411 RAD1 other 0.0616785245376442 1 1 2.63441218329652 -2.1753589643974 1.08017003564789e-05 67.6425198664059 29.7394530028551 2.27450450618281 0.0234217962917115 -157.893089059967 61.9946012441483 -2.54688450108985 0.0112123629484173 BRIX1 essential 0.0597982131734672 1 1 2.27450450618281 -2.54688450108985 0.967178906310533 -22.0132632060368 111.924168291115 -0.196680158915993 0.844169064382791 -56.8917307252548 233.294539633495 -0.24386224733177 0.80745169022715 PRLR other 1 1 1 -0.196680158915993 -0.24386224733177 0.624067352892731 -56.8072664940175 107.912193377709 -0.526421201496511 0.598863273331052 -159.063926503035 164.507519023616 -0.966909764654593 0.334125168195641 SLC12A7 other 1 1 1 -0.526421201496511 -0.966909764654593 0.250285843616111 105.046604161902 76.4453254603306 1.37414032224134 0.170104088106777 -47.421404070432 151.383859190071 -0.313252709530227 0.754238470941479 GNPDA1 other 1 1 1 1.37414032224134 -0.313252709530227 0.997799463881001 0.272612241786854 62.7299350657136 0.00434580781091636 0.996534545623385 -7.3201006174251 124.223418499515 -0.0589268972456565 0.953037332478531 PCDH12 other 1 1 1 0.00434580781091636 -0.0589268972456565 0.000197689297693891 93.293065902579 50.8744717330775 1.83378937853269 0.0673667072848115 -258.503505253104 109.195955662803 -2.36733589338568 0.0183524303576018 NUP155 essential 0.941594124916003 1 1 1.83378937853269 -2.36733589338568 0.0121947237541347 -871.371339278908 793.858109916877 -1.0976411633184 0.272967027685426 -4687.71227989937 1572.06871191771 -2.98187492974209 0.00302545170221845 FGF1 other 1 1 1 -1.0976411633184 -2.98187492974209 0.012019595348177 117.883786874 157.01132526548 0.750797986544458 0.45317925030221 -730.265828188121 310.927845647936 -2.348666542446 0.0192864480597504 NR3C1 other 1 1 1 0.750797986544458 -2.348666542446 0.00371896221195336 1043.4549632353 737.464422572424 1.41492244411672 0.15780666993099 -3118.00980392155 1582.92211724774 -1.96978093233222 0.0494974887028148 LIFR other 1 1 1 1.41492244411672 -1.96978093233222 0.635319976941978 -2.78748898678416 2.94332386104708 -0.947054798717432 0.344136644261351 -3.50353891336264 6.26121486357547 -0.559562160012178 0.576066116639833 C9 other 1 1 1 -0.947054798717432 -0.559562160012178 0.00159300273640321 25.2045814977975 26.9063692369151 0.936751490915288 0.349406171782817 -147.455521292217 57.2368407094323 -2.5762344578169 0.0103171208749689 TTC33 other 1 1 1 0.936751490915288 -2.5762344578169 0.000576956979841121 120.768087447731 37.4242239215529 3.22700312238618 0.00134504368634034 -12.365094270411 66.7320189339916 -0.185294772553518 0.853083806452053 RARS essential 1 1 1 3.22700312238618 -0.185294772553518 0.00130034322684161 -126.89661512494 161.090818765161 -0.787733379826757 0.431280708139696 -987.077493444262 284.524811181449 -3.46921412352603 0.000573910315134131 WWC1 other 1 1 1 -0.787733379826757 -3.46921412352603 0.0230307131157744 286.579162178156 118.22514675776 2.42401189626221 0.0157540641167587 -54.5446398316863 234.10771557541 -0.232989500997956 0.815878397048004 TCERG1 essential 1 1 1 2.42401189626221 -0.232989500997956 0.0259425759283916 873.279415557832 1960.51622942213 0.445433402923288 0.656226648773751 -8826.42375092925 3882.18571433836 -2.27357071515924 0.0234750868305213 DPYSL3 other 1 1 1 0.445433402923288 -2.27357071515924 1.17845614750215e-06 438.46118763113 216.032907524797 2.02960369628318 0.0430008890737877 -1421.79510300881 405.904947116505 -3.50277845369723 0.000507752205924513 CSNK1A1 essential 0.00709312755181544 1 1 2.02960369628318 -3.50277845369723 0.00411140461953172 147.061966006874 74.3358055948947 1.97834630068197 0.0485157839080351 -214.416939228485 139.669791906102 -1.53517046386547 0.12546396983151 HMGXB3 other 1 1 1 1.97834630068197 -1.53517046386547 0.00163764140758539 417.840780428606 191.009170345338 2.1875430361441 0.0292320386496549 -515.044306510342 357.973492318299 -1.43877777981499 0.150929313741704 ERGIC1 other 1 1 1 2.1875430361441 -1.43877777981499 0.923870829028199 63.252120769863 200.189781692957 0.315960785984954 0.752182778425981 -29.1443165973854 376.137245396363 -0.0774831978329451 0.938274539451251 PDGFRB other 1 1 1 0.315960785984954 -0.0774831978329451 0.155969479090072 6.14729073996844 167.18159650627 0.0367701401854832 0.970685073073837 -522.756397088585 313.31783623005 -1.66845399986982 0.0959419135936291 ATP6V0E1 other 1 1 1 0.0367701401854832 -1.66845399986982 3.60923979397471e-05 53.9225636878277 14.3009666954851 3.77055375598151 0.000185282100611183 -11.4276182773971 26.8016817321118 -0.426376911404979 0.670043171635194 BNIP1 essential 0.18910481786476 1 1 3.77055375598151 -0.426376911404979 0.111547279792878 181.988576627581 108.532237714979 1.6768158517611 0.0942936277955601 -58.1359280226423 203.40208846365 -0.285817753700359 0.775153141121785 STC2 other 1 1 1 1.6768158517611 -0.285817753700359 4.33070370025937e-05 189.386221330488 199.972961307866 0.94705914285542 0.344132028245896 -1328.70917078906 383.513961993241 -3.4645653156494 0.000583525050736599 CPEB4 other 0.224590293895451 1 1 0.94705914285542 -3.4645653156494 0.858305798256314 -34.7526339219476 63.0789622468063 -0.550938580536131 0.58195668338181 -25.8882252559733 124.077439187779 -0.208645708885029 0.834821818221176 HRH2 other 1 1 1 -0.550938580536131 -0.208645708885029 0.0167665782593915 465.656117888638 378.244320492313 1.23109877045226 0.218946566293342 -1239.66332200231 725.383332046403 -1.70897685021939 0.0881636169711236 DBN1 other 1 1 1 1.23109877045226 -1.70897685021939 8.81007487116343e-05 63.6873984473731 23.0770144658989 2.75977633681707 0.0060267047911082 -86.2721610398991 46.6844243487185 -1.84798596627158 0.0652783348628428 ZNF346 other 0.439182232327497 1 1 2.75977633681707 -1.84798596627158 0.024126990808561 -113.837395438406 138.900563253133 -0.819560358664264 0.412912511665095 -761.941997151505 280.993576823703 -2.71159933890429 0.00695935473142811 UNC5A other 1 1 1 -0.819560358664264 -2.71159933890429 0.417074872570848 -79.710966852832 75.9714372897147 -1.04922283553563 0.294654155103481 -150.672183941394 122.121247260934 -1.23379172192252 0.217942158542347 CNTN3 other 1 1 1 -1.04922283553563 -1.23379172192252 8.35368990990971e-05 582.191739588483 134.234570773759 4.33712221995121 1.79516889329995e-05 322.61215626411 305.112361387456 1.05735524708693 0.290934967995846 SMC4 essential 0.417851569293684 1 0.154312718068064 4.33712221995121 1.05735524708693 1.76126545235198e-13 228.290875065757 103.97099663918 2.19571690611004 0.0286359567004435 -770.090444446357 160.368200646582 -4.80201462223471 2.15987708823076e-06 SELENOK other 1.37889472264637e-09 0.0188233288239311 1 2.19571690611004 -4.80201462223471 8.88582172600728e-11 14.447976405047 42.0170211204135 0.343860083837016 0.731116522038558 -349.601398219453 64.8084012986267 -5.39438392575903 1.12758425055037e-07 ACTR8 essential 6.55062777641257e-07 0.00102215512312391 1 0.343860083837016 -5.39438392575903 5.55455208774579e-14 176.353934900917 56.4152241226169 3.12599901256471 0.00188996052246833 -588.83519954323 112.052104970259 -5.25501238642077 2.31652718538335e-07 TIMMDC1 other 4.39253979098937e-10 0.00208348455053378 1 3.12599901256471 -5.25501238642077 4.10167490126639e-07 108.5107091861 63.9905916288615 1.69572911304604 0.0906543663337265 -534.322798667299 133.092467719658 -4.0146734659153 7.01290458513539e-05 CRBN other 0.00255042145360744 0.56460894814925 1 1.69572911304604 -4.0146734659153 0.214775249886088 229.591204526326 317.079707031869 0.7240804108074 0.469404704741876 -765.699920508745 671.722846287015 -1.1399045376247 0.25495189503207 BCL6 og 1 1 1 0.7240804108074 -1.1399045376247 0.117483189630044 21.2131925348756 19.9829200904338 1.06156619947806 0.289023031261919 -44.1537497197604 39.6948328823532 -1.11232990577445 0.266612084117894 ARL6 other 1 1 1 1.06156619947806 -1.11232990577445 0.173267594237331 -1.77383474576225 46.3759389578192 -0.0382490314077656 0.969506594792732 -168.710644581407 97.7752790784546 -1.72549386891583 0.0851454362577968 NPHP3 other 1 1 1 -0.0382490314077656 -1.72549386891583 0.632933589808611 -25.3106704438165 60.988998241445 -0.41500387239705 0.67834227043702 -112.916228247675 118.084929037536 -0.956228954600821 0.339484047738312 CD86 other 1 1 1 -0.41500387239705 -0.956228954600821 0.0197191523360559 40.8182447108092 402.370809914974 0.101444348608277 0.919244367449566 -2139.78613144556 848.344216504787 -2.5223088574371 0.012013732384341 AMOTL2 other 1 1 1 0.101444348608277 -2.5223088574371 5.91924957114738e-06 86.5029820905131 34.6056348945318 2.49967909429056 0.0127971144957429 -176.270573882988 67.0067658087037 -2.63063844009752 0.00882425855107769 NIT2 other 0.0336509338119729 1 1 2.49967909429056 -2.63063844009752 0.162554805288526 -81.4726156751678 110.784576428256 -0.735414786984626 0.462480521843742 -407.988061513562 214.497519605007 -1.90206423955327 0.0578184863408565 FAM162A other 1 1 1 -0.735414786984626 -1.90206423955327 2.40431953173136e-08 202.316841802274 63.3408423518726 3.19409774625918 0.00150394993649347 -527.309883655449 148.675863643494 -3.5467080582755 0.00043215400928457 OGG1 other 0.000160824933477511 1 1 3.19409774625918 -3.5467080582755 1.01909481637757e-05 -29.0075542965094 94.2120546108026 -0.307896419586027 0.758307511556858 -807.813638203164 182.410337994978 -4.42855184131835 1.19962922599198e-05 KPNA1 other 0.0565801442052828 0.101212717796944 1 -0.307896419586027 -4.42855184131835 6.28610469401747e-06 292.453503701453 108.948267617003 2.68433367595659 0.0075430443333854 -620.188621843627 229.692826753845 -2.70007832028757 0.00720083540277679 PCCB other 0.0356610719291611 1 1 2.68433367595659 -2.70007832028757 4.20538851926685e-08 160.410479159328 101.717431813784 1.57702053914411 0.1155177159498 -640.434184551775 172.663934734612 -3.70913697487629 0.000234892376217828 UBE3A other 0.0002770509956493 1 1 1.57702053914411 -3.70913697487629 0.00127765649304582 23.7325884063405 51.493400959688 0.460886015761898 0.645109143664559 -358.011877403621 112.461370628983 -3.18342089733838 0.0015592105782771 ARMC8 other 1 1 1 0.460886015761898 -3.18342089733838 0.000120915683039367 146.683120720383 123.587037912561 1.18688110984716 0.235917850070246 -901.185184316669 269.91356982817 -3.33879169131946 0.000913333045170337 SLC25A36 other 0.593333256674174 1 1 1.18688110984716 -3.33879169131946 2.52671129686961e-07 147.754232717381 43.407610409565 3.40387852091538 0.000725493214761414 -264.014621048682 94.8020381526216 -2.78490448299904 0.00558649676308067 RNF7 other 0.00159132277476848 1 1 3.40387852091538 -2.78490448299904 0.150828741826031 279.182030297347 166.645582090081 1.67530412025225 0.0945882883651275 -97.2167362348752 363.95324880147 -0.267113253020871 0.789507684857239 TFDP2 other 1 1 1 1.67530412025225 -0.267113253020871 0.00816469217282641 18.1144357940159 54.1753115157681 0.334366989080322 0.73826269171663 -322.591970734453 118.318651978048 -2.72646759696269 0.00665851142758136 XRN1 other 1 1 1 0.334366989080322 -2.72646759696269 0.113763215157239 -48.3688652523215 305.712776229017 -0.158216695582546 0.874358966100013 -1227.23944544 629.882857794021 -1.94836139808289 0.0520100010037146 KAT2B other 1 1 1 -0.158216695582546 -1.94836139808289 0.00407705919082215 402.776406646765 121.645283160708 3.31107295064329 0.00100667263707132 427.084584428504 197.653943149167 2.1607693609542 0.031257132311586 WNT5A ts 1 1 1 3.31107295064329 2.1607693609542 0.0332108110719773 -24.8256756756761 36.9933098153946 -0.671085550321453 0.502522208597354 -138.520608108108 57.5910049709445 -2.40524728085565 0.0165781891474599 PFKFB4 other 1 1 1 -0.671085550321453 -2.40524728085565 0.0024969909848268 343.833285031155 197.549338930765 1.7404932200338 0.0824812032283854 -682.429877312467 381.128374291509 -1.79055122458688 0.0740621915453675 FGF12 other 1 1 1 1.7404932200338 -1.79055122458688 0.000642234560738 147.822403982929 105.03794213148 1.40732387728897 0.160045492283831 -320.593652204836 163.522557933286 -1.96054694995435 0.0505696765902474 PRKAR2A other 1 1 1 1.40732387728897 -1.96054694995435 0.0790037715408956 143.076786134502 77.7083230063147 1.84120285445969 0.0662679085520027 -21.8196267610678 142.181673744179 -0.153463003961586 0.878103840336786 HES1 other 1 1 1 1.84120285445969 -0.153463003961586 3.22233181480712e-07 -63.70597203049 75.060183150388 -0.848731902277016 0.396495159754266 -579.25276994178 117.039547890609 -4.94920546414942 1.06569641371742e-06 USP4 other 0.00201589078334334 0.00938665401202305 1 -0.848731902277016 -4.94920546414942 8.64614414325733e-07 42.5405417510209 88.3939150321837 0.481260975210026 0.630571363306769 -648.722773607546 154.939037493903 -4.18695497339122 3.41915816064329e-05 ACAP2 other 0.00526204332558641 0.281499291365762 1 0.481260975210026 -4.18695497339122 8.79101898815811e-07 682.500045848858 688.670701180222 0.991039759175483 0.322217099656229 -3750.9851633136 1042.29809543227 -3.59876428802065 0.000356498957681642 GNAI2 other 0.00534757685049658 1 1 0.991039759175483 -3.59876428802065 7.71520227594014e-09 125.288163981497 78.212150835464 1.60190152863929 0.109898301259769 -734.010767267503 156.824409358343 -4.68046250115498 3.82179651828558e-06 TFG other 5.2980294028881e-05 0.0329821039528046 1 1.60190152863929 -4.68046250115498 0.967362451566933 -0.819337209089111 5.55352064887598 -0.147534737132011 0.882778320469505 0.662479138775255 8.40521309436746 0.078817649396563 0.937213908954841 HYAL1 other 1 1 1 -0.147534737132011 0.078817649396563 2.92422931608405e-17 105.127459790564 52.8982374278462 1.98735279098778 0.0475099802441954 -471.087345107317 80.0610974567066 -5.88409802104024 7.99738843087633e-09 TUSC2 other 2.42711033234976e-13 7.39598482087443e-05 1 1.98735279098778 -5.88409802104024 7.49999428955778e-09 91.4438718433081 41.0523602969078 2.22749364913364 0.0264251640874179 -205.096404839193 62.132448610252 -3.30095480584925 0.00104294451656387 NPRL2 other 5.15324607635515e-05 1 1 2.22749364913364 -3.30095480584925 0.000475419642429431 1121.49926445826 451.022335063484 2.48657145615728 0.0132696119889921 -1471.46705127523 904.351952327074 -1.62709556549179 0.104435941847562 RPL24 essential 1 1 1 2.48657145615728 -1.62709556549179 9.14005649848063e-12 54.1136776275978 16.1275317352679 3.35536017016549 0.000862126434389773 -77.3472530428352 24.4089019365646 -3.16881329786363 0.00163861187012044 CYB561D2 other 6.8916025998544e-08 1 1 3.35536017016549 -3.16881329786363 0.0156763770921699 -1.69885819025641 54.2004476355057 -0.0313439881840297 0.975009487522645 -224.643255923454 91.8902427297139 -2.44469107110991 0.0148908014925783 C3orf14 other 1 1 1 -0.0313439881840297 -2.44469107110991 0.12450962552598 -22.2083084567539 75.1876440561688 -0.295371782631775 0.767850494855652 -303.340841245693 155.106472168686 -1.95569428537962 0.0511394504527293 CBLB other 1 1 1 -0.295371782631775 -1.95569428537962 0.000467573486912856 -132.69405086568 176.575332947191 -0.751486907321111 0.452764188865749 -1347.08439118423 354.064012070687 -3.80463516556237 0.000162249989856899 BBX other 1 1 1 -0.751486907321111 -3.80463516556237 0.0261276481970409 127.90816018335 57.0983297124386 2.2401383863158 0.0255838690030306 -41.5349734834023 114.492003855188 -0.362776194710824 0.716947470758153 IFT57 other 1 1 1 2.2401383863158 -0.362776194710824 0.243098406873285 -1.82168509149957 100.053089894683 -0.0182071847397926 0.985481996406779 -264.609372722918 183.133824554294 -1.44489623021262 0.149213655782668 IQCG other 1 1 1 -0.0182071847397926 -1.44489623021262 0.492053029927633 75.3246715119981 79.4643142138694 0.947905638614965 0.343704989338113 -18.2626793195378 128.285168048356 -0.142360021796548 0.886861702550991 GBE1 other 1 1 1 0.947905638614965 -0.142360021796548 2.68358485347235e-06 53.0486307837582 27.5936299224517 1.92249555179382 0.0551916547565339 -176.989882638609 53.425895247227 -3.31281079745305 0.00100023291357095 UMPS essential 0.0157338579959084 1 1 1.92249555179382 -3.31281079745305 3.94178234249492e-21 613.671546656353 127.040426130575 4.83052179017101 1.89148540133066e-06 -1117.18407295922 225.734918377807 -4.94909729069659 1.06880394969955e-06 NCBP2 essential 3.40845919155535e-17 0.00941115445161992 0.0168417860134482 4.83052179017101 -4.94909729069659 0.00309762304876443 61.1960903628211 51.54391908089 1.18726110575301 0.235769603547377 -227.543584087625 99.8009802849956 -2.27997343751376 0.0230902752394078 SNX4 other 1 1 1 1.18726110575301 -2.27997343751376 0.562683887967417 -42.6577226174898 79.3615691615215 -0.537511078323946 0.591188233365395 -141.664566250836 132.31942192324 -1.07062564355078 0.284928741233103 FRMD4B other 1 1 1 -0.537511078323946 -1.07062564355078 0.000355869766934371 131.289571765414 72.1932366215167 1.81858547849459 0.0696590621773349 -324.06112928172 139.782847584154 -2.31831826924705 0.0208927657327713 SLC41A3 other 1 1 1 1.81858547849459 -2.31831826924705 0.540068495313606 2.99350929236083 3.47530760346913 0.861365275802534 0.389509269753345 -1.45692299890967 6.72900143805148 -0.216513997258345 0.828688150810574 ROPN1B other 1 1 1 0.861365275802534 -0.216513997258345 0.227748837175062 90.0929960016557 167.095747267339 0.539169891963285 0.590044840509109 -424.413050757321 341.402131783936 -1.2431470434576 0.214481727616253 PLXNA1 other 1 1 1 0.539169891963285 -1.2431470434576 0.417170425684892 -319.710103871584 292.778956770794 -1.09198457224463 0.275440163339741 -664.481991096725 566.869162157664 -1.17219639990209 0.241755388535838 ATP6V1A essential 1 1 1 -1.09198457224463 -1.17219639990209 0.25826925367615 112.29746311871 71.59410493223 1.56852946517048 0.117483052418414 32.3993224478546 146.277690765644 0.22149189174556 0.824813146912085 ABTB1 other 1 1 1 1.56852946517048 0.22149189174556 0.0183344064427553 221.548945264032 396.145144548059 0.559262049057261 0.576270047567619 -1837.85649287979 809.385032571668 -2.27068257864906 0.0236532253630731 PODXL2 other 1 1 1 0.559262049057261 -2.27068257864906 0.00650412070046244 -827.590853551584 1314.64153011206 -0.629518263797008 0.529339538529482 -5928.27465506154 2069.13706918539 -2.86509518549947 0.00437036687422019 CSPG5 other 1 1 1 -0.629518263797008 -2.86509518549947 0.00128357963212789 -5.2462431291135 31.4345508163629 -0.16689416558746 0.867530520108221 -146.321905447168 48.9307512239715 -2.99038747182536 0.00294368969574162 KLHL18 other 1 1 1 -0.16689416558746 -2.99038747182536 5.81516226821186e-15 203.730236618002 138.119636641155 1.47502731380121 0.140925278885344 -1203.09053351105 214.995837513789 -5.59587826175418 3.88020946285207e-08 SCAP essential 4.67015681760095e-11 0.000355271978418736 1 1.47502731380121 -5.59587826175418 0.562699782069696 -3.00841031297395 6.86897157549122 -0.437970994625758 0.661624204848741 -15.0550412637135 14.0343580096268 -1.07272746308642 0.283986792095899 EFCC1 other 1 1 1 -0.437970994625758 -1.07272746308642 0.000802486638335444 5.07593409623609 5.06045921057478 1.00305800027574 0.31638923081553 -29.7638809556637 10.3392910385193 -2.87871584664535 0.00418940920890135 KIAA1257 other 1 1 1 1.00305800027574 -2.87871584664535 0.547184662062719 52.1299975866791 81.2260223171278 0.641789368721638 0.521347216409134 -94.0316949561572 171.254038723597 -0.549077240204091 0.583233528895948 NEK11 other 1 1 1 0.641789368721638 -0.549077240204091 0.000132598540811747 9.76223419944896 64.6811904289811 0.150928486855352 0.880101931518555 -521.879736143509 136.371507238972 -3.82689717749462 0.000148740314080163 MRPL3 essential 0.647080879161327 1 1 0.150928486855352 -3.82689717749462 0.542639535138028 -105.341009286181 164.953687650853 -0.638609604831323 0.523410707624911 -389.351139667947 360.258158478264 -1.08075592600754 0.280400407879153 PLSCR4 other 1 1 1 -0.638609604831323 -1.08075592600754 8.03354812784909e-07 103.453500100868 48.4325733316899 2.1360314553672 0.0332344946604577 -193.647367359291 73.3023473395793 -2.64176215888699 0.00854482507432837 HEMK1 other 0.00490046435798794 1 1 2.1360314553672 -2.64176215888699 0.287859577759353 -2.80207970363314 13.9506074588463 -0.200857182162079 0.840904127413247 23.7803412376744 21.1141428836153 1.12627547178948 0.260669887618514 CISH other 1 1 1 -0.200857182162079 1.12627547178948 0.00321522484693096 110.328809580576 83.3992766801922 1.32289887841173 0.1865640004313 -214.797219726008 126.224198437977 -1.70171189347304 0.08952391779257 MAPKAPK3 other 1 1 1 1.32289887841173 -1.70171189347304 0.00117674361599554 114.930025790687 79.7545130519422 1.44104730118327 0.150285818543572 -278.615153160491 135.673648491903 -2.05356866464101 0.0406106655512057 ACVR2B other 1 1 1 1.44104730118327 -2.05356866464101 8.00041313313495e-10 272.122116053336 103.922564316354 2.61850848122802 0.00913836862791861 -644.434111457169 176.795307660986 -3.64508606016231 0.000299464520866703 WDR48 other 5.71709522493824e-06 1 1 2.61850848122802 -3.64508606016231 0.00022882208116806 315.112021199712 90.0247310970141 3.50028283739204 0.000512510582760606 -103.686340640806 187.904784068858 -0.551802558698077 0.581365694182664 COMMD2 other 1 1 1 3.50028283739204 -0.551802558698077 1.27854702534711e-05 141.44383296544 127.141358112956 1.11249270154703 0.266537973623389 -712.455958392544 216.295620415887 -3.29389914147431 0.00106843979581751 GORASP1 other 0.0703328718643444 1 1 1.11249270154703 -3.29389914147431 4.68281848003755e-07 113.20069773858 44.6396311303047 2.53587887875111 0.0115647038078584 -161.542491745505 68.2145645476103 -2.36815250257525 0.0183124986726003 RRP9 essential 0.00290100604838326 1 1 2.53587887875111 -2.36815250257525 0.000332875020838089 96.2193426661812 56.2869252171846 1.70944393027184 0.0880802948617263 -163.205589621732 86.0129888216652 -1.89745283657232 0.0584285937253418 ABHD14B other 1 1 1 1.70944393027184 -1.89745283657232 2.9915767948058e-11 113.403247452269 67.3438859487002 1.68394273443998 0.0929068284873437 -541.857072628114 112.772872359445 -4.80485298717081 2.13248324302134e-06 EIF1B other 2.23022050052772e-07 0.01859098891266 1 1.68394273443998 -4.80485298717081 8.8353605189947e-10 77.4512428468454 70.315722787657 1.10147830067447 0.271296234921113 -489.007980088348 107.450628272648 -4.55100158974897 6.93305582629371e-06 ABHD14A-ACY1 other 6.30226265819892e-06 0.0591389661982853 1 1.10147830067447 -4.55100158974897 0.188734242195364 -24.5010330707094 30.5411658271032 -0.802229790749062 0.422855091870609 -88.3027892909154 49.0889150804153 -1.79883358893269 0.0727333033648077 VIPR1 other 1 1 1 -0.802229790749062 -1.79883358893269 0.0577668221595787 -77.410814426823 50.2829991665636 -1.53950272875327 0.124405362199072 -182.092106237008 76.0683616724332 -2.39379555748993 0.0170958231462609 DNAH1 other 1 1 1 -1.53950272875327 -2.39379555748993 1.21923283232436e-10 -404.696557260741 237.283157917333 -1.7055426976479 0.0888022357834798 -2447.73070460402 381.385990795412 -6.4179879798392 3.59254412995842e-10 ZBTB47 other 8.95038822209315e-07 3.38345806159484e-06 1 -1.7055426976479 -6.4179879798392 0.223575109941749 30.4640230013851 242.146317546476 0.12580832659385 0.899941376656316 -511.647137896268 389.202563070647 -1.31460372167024 0.189331050784675 NKTR other 1 1 1 0.12580832659385 -1.31460372167024 2.74294949598142e-05 156.218868646903 53.2607380088085 2.93309620721115 0.00353250563818424 -119.178684235719 88.8015463780376 -1.34207892876508 0.18026726024529 FOXP1 other 0.145787765711413 1 1 2.93309620721115 -1.34207892876508 6.21009319857364e-20 128.382443491984 99.7981918902889 1.28642053588625 0.198975881362933 -1094.23336811634 153.931932736681 -7.10855342788524 4.79511493934338e-12 SPCS1 other 5.29969353566274e-16 4.58796597396374e-08 1 1.28642053588625 -7.10855342788524 5.31752213678134e-12 59.1841717188266 63.8369523366011 0.927114618610844 0.354377606265189 -527.493527773224 98.4641631984177 -5.35721333161851 1.36835164602841e-07 NEK4 other 4.03280878853497e-08 0.00123808456932651 1 0.927114618610844 -5.35721333161851 4.60235368009603e-14 493.053262316921 581.707459228276 0.847596596012422 0.397125587319372 -5506.56052584743 966.447612974052 -5.69773307101673 2.23154266140143e-08 NCL essential 3.64506411463606e-10 0.000205011824302949 1 0.847596596012422 -5.69773307101673 0.0176805775190387 -503.302250998426 401.896946295621 -1.25231668376056 0.211127362691876 -1722.5913968439 628.921719078163 -2.73895994459974 0.00641661771603317 EFHD1 other 1 1 1 -1.25231668376056 -2.73895994459974 2.55256963176362e-20 472.022853613352 344.342436834575 1.3707948922953 0.171140921342259 -2966.22897130664 504.136888233446 -5.88377688786205 7.97573627591573e-09 HDLBP other 2.18653114656872e-16 7.37675848159446e-05 1 1.3707948922953 -5.88377688786205 8.23207728062113e-17 11.1852995676367 91.6590326595919 0.122031612630882 0.90292994996829 -823.620037621427 134.194030594299 -6.13753111054119 1.87853569061075e-09 PPP1R7 essential 6.80381187243337e-13 1.75192238506359e-05 1 0.122031612630882 -6.13753111054119 7.43499107262069e-06 50.8776405188393 22.8562640181209 2.22598235995622 0.026523503187545 -48.2195912179234 33.4628688948762 -1.44098796099658 0.150302574390783 PASK other 0.0418441297567093 1 1 2.22598235995622 -1.44098796099658 6.00806860418349e-27 466.288573193333 121.912968337004 3.82476597489096 0.000149899167623343 -887.637787073951 178.487511030324 -4.97310866149702 9.47743707822943e-07 STK25 other 5.37181413900046e-23 0.00836573370895312 1 3.82476597489096 -4.97310866149702 0.0124065967363415 -396.859737742125 392.222949107246 -1.0118218188034 0.312181870323648 324.693648967408 503.652481916894 0.644677948834141 0.519473403417794 DHCR24 other 1 1 1 -1.0118218188034 0.644677948834141 1.13614487158463e-40 14.0871478265488 28.9405160431001 0.486762150528667 0.626670378521527 -281.918221407898 36.9793722288003 -7.62366163664439 1.54430585878442e-13 DNAJC16 other 1.06252268390595e-36 1.48994629255521e-09 1 0.486762150528667 -7.62366163664439 1.21645181045909e-37 21.6801124398142 10.8483675729134 1.99846772282549 0.0462836299396239 -81.6231384279367 13.8613532318528 -5.88854039448115 7.76566103095094e-09 MORN1 other 1.12898892528708e-33 7.18401301973272e-05 1 1.99846772282549 -5.88854039448115 4.04671339553184e-38 91.75197223431 19.4474265786796 4.71794928049239 3.21131109253003e-06 -84.009313718609 24.9815913629102 -3.36284876724612 0.000839337295414577 GPX7 other 3.76020608712819e-34 1 0.028391201369058 4.71794928049239 -3.36284876724612 3.94672151448764e-83 555.625479021323 128.039079737157 4.33949916042766 1.77579676992224e-05 -1525.69042939962 164.475230464858 -9.27611060393437 8.17815717606431e-19 SCP2 other 3.8800219208928e-79 8.0121405853902e-15 0.152700764245614 4.33949916042766 -9.27611060393437 2.85087186849973e-42 -12.2403395060507 36.0915675003548 -0.339146796711735 0.734661687975873 -389.681893664881 46.1190801125068 -8.44947238137141 4.36429339517562e-16 CEP104 other 2.67782394608179e-38 4.25300391359864e-12 1 -0.339146796711735 -8.44947238137141 1.0670674223581e-38 508.564106605303 216.280487142043 2.35141002928896 0.0191445955960704 -1599.8125362277 277.725218239334 -5.76041508354864 1.58252397200597e-08 TMEM59 other 9.92906236504215e-35 0.00014575045782175 1 2.35141002928896 -5.76041508354864 1.26047779238144e-72 134.837113272076 26.3893031189289 5.10953671888964 4.83111659251446e-07 -246.480760575861 33.8864363805281 -7.27372916431821 1.62499157370946e-12 LRRC42 other 1.23274728094905e-68 1.56080440654794e-08 0.00436588006465532 5.10953671888964 -7.27372916431821 2.72006678418195e-53 172.407555902612 30.4110304104069 5.66924413858772 2.60618354749402e-08 -162.959926855782 38.8576241515918 -4.19376970192621 3.32185075689773e-05 WRAP73 other 2.61072009945784e-49 0.273687283860804 0.000240759236117497 5.66924413858772 -4.19376970192621 2.45501496622143e-44 278.160640829642 58.8285510179002 4.72832724955276 3.0570494588128e-06 -314.855008659623 75.5415913198861 -4.16796897124324 3.70479162166442e-05 MRPL37 other 2.31728862661641e-40 0.304348631719732 0.0270518306610345 4.72832724955276 -4.16796897124324 5.20354049253949e-39 105.147066096727 74.5678098822712 1.41008655427503 0.159225463750343 -612.778047832691 94.9056270059354 -6.4567093349941 2.85198351881884e-10 ICMT other 4.84501655260352e-35 2.68770926813487e-06 1 1.41008655427503 -6.4567093349941 3.85083181102724e-29 878.217984950711 330.157996076897 2.65999308024079 0.0081015955192466 -1693.07159359877 420.206140936303 -4.02914529003854 6.60220369872404e-05 RPL22 other 3.47345029354657e-25 0.53233568422812 1 2.65999308024079 -4.02914529003854 0.00435722284142247 -219.839878811784 245.186991900606 -0.896621297515255 0.370413561803035 285.033369139726 313.462976049898 0.909304737457585 0.363689369346532 CHD5 other 1 1 1 -0.896621297515255 0.909304737457585 6.91018755261072e-45 206.9055105426 72.1011472295478 2.86965628832336 0.0043085307446399 -499.27773147147 90.0897874352287 -5.54200143751514 5.17861131386779e-08 STXBP3 other 6.52874519970661e-41 0.000472858999069268 1 2.86965628832336 -5.54200143751514 1.67544906751798e-62 67.5744902777852 34.7055461339494 1.94708044693995 0.0521638610006268 -389.338396392377 44.3698244032248 -8.77484645542297 3.85126079772253e-17 PHF13 other 1.62635840983971e-58 3.76268179937491e-13 1 1.94708044693995 -8.77484645542297 1.1457810015324e-06 79.9226245336845 54.0911115966607 1.47755559415456 0.140250394511548 -98.5147579547953 69.2385109718094 -1.42283183985435 0.155501636316107 ERRFI1 other 0.00690562209623579 1 1 1.47755559415456 -1.42283183985435 8.64372113791167e-49 962.420232609173 219.594565569886 4.38271425393213 1.47108079232017e-05 -1373.93838490236 281.088709193747 -4.88791737257344 1.43580378463081e-06 PARK7 other 8.23228001174707e-45 0.0126006140139199 0.126910139953461 4.38271425393213 -4.88791737257344 0.0445645487326954 -13.9493418428403 33.841918182626 -0.412191228864848 0.680400924475695 47.1999438608933 45.0091689244879 1.04867396996556 0.294906495872054 KIAA1324 other 1 1 1 -0.412191228864848 1.04867396996556 0.0633557338681493 68.1077030902902 31.5377111905559 2.15956391631506 0.0313485332483542 53.4791845452309 40.4954786897066 1.32062112303971 0.187317336092591 OPRD1 other 1 1 1 2.15956391631506 1.32062112303971 0.000239618901496946 265.982449142404 232.170468159528 1.14563428867983 0.252572055416686 -395.678749870732 308.782728102995 -1.28141477440005 0.200725984465891 AMPD2 other 1 1 1 1.14563428867983 -1.28141477440005 4.47278625193232e-103 260.428659238126 85.1819939774162 3.05732053310671 0.00237000453841299 -1412.03858479514 109.381979761783 -12.9092432580791 1.55566844180752e-32 SRSF4 other 4.40614173677852e-99 1.53248898202458e-28 1 3.05732053310671 -12.9092432580791 1.60629076984101e-32 82.9229617488059 21.8294568082977 3.79867270528169 0.000166024692783042 -99.5371619550961 28.0311494404437 -3.55094828225212 0.00042544409200316 MECR other 1.46831039271167e-28 1 1 3.79867270528169 -3.55094828225212 0.290314115515128 -46.3217405464508 44.0934470648872 -1.05053570609448 0.2940511524887 -14.5565843023065 56.8896161252444 -0.2558741874837 0.798168109857183 KCNC4 other 1 1 1 -1.05053570609448 -0.2558741874837 5.88455579022323e-73 192.413032514302 35.9551017682484 5.3514806815043 1.40967141625118e-07 -326.802317171622 46.1698538659483 -7.07826189184993 5.83575370306189e-12 WDR77 essential 5.75627247399637e-69 5.57781338938656e-08 0.00128674806875408 5.3514806815043 -7.07826189184993 8.49444845453884e-76 328.836222793109 90.6001611754039 3.62953242606793 0.000317451120749012 -1054.29673613628 116.339434349584 -9.06224739728632 4.28567325616756e-18 ATP5F1 essential 8.32116170606624e-72 4.19567411778805e-14 1 3.62953242606793 -9.06224739728632 3.52402016293212e-74 74.9746804520159 67.3555609843164 1.11311789785959 0.266268307081316 -963.201145802141 86.4911029246783 -11.1364188134004 1.55915285646897e-25 RAP1A other 3.44895853346167e-70 1.53389458019418e-21 1 1.11311789785959 -11.1364188134004 2.35665993743621e-91 302.989204849299 60.4016088506705 5.01624394804404 7.68406739512301e-07 -750.789559422305 77.6261495717374 -9.67186397321525 3.55730439002843e-20 HDAC1 other 2.31895337843723e-87 3.48935987617889e-16 0.00691566065561071 5.01624394804404 -9.67186397321525 1.81974333768953e-52 122.886964333559 83.1240960890328 1.47835549636458 0.140031397297543 -879.967237904109 106.739438366959 -8.2440684658549 1.95541205732066e-15 CAPZA1 other 1.74458793784296e-48 1.90163822574434e-11 1 1.47835549636458 -8.2440684658549 1.27466571099687e-78 106.821098593884 30.0339523263914 3.55667803667712 0.000416726250987993 -366.218211533066 38.5986419878783 -9.48785223190169 1.549833943666e-19 S100PBP other 1.25044706248793e-74 1.51930221497578e-15 1 3.55667803667712 -9.48785223190169 1.72029774580955e-30 41.4828908377545 40.2225192972485 1.03133497261053 0.302955514040058 -305.162672940379 51.6926512146315 -5.90340533460592 7.16595160148311e-09 RNF19B other 1.55962193635094e-26 6.63352139749291e-05 1 1.03133497261053 -5.90340533460592 0.0115687029560243 -73.9519817436384 34.7881067007555 -2.12578345754103 0.0340827282409772 -131.008371911605 44.7085239193994 -2.93027728107927 0.00356449198904055 TRIM62 other 1 1 1 -2.12578345754103 -2.93027728107927 5.47046350219296e-06 -116.357980425223 72.6391946147787 -1.60186220458934 0.109907000923323 109.859492575839 93.275803303835 1.17779197481671 0.239519092587093 DLGAP3 other 0.0312303609151636 1 1 -1.60186220458934 1.17779197481671 9.79654112285852e-21 762.649545304101 383.44742731359 1.98892857528652 0.0473307919613621 -1790.18887522962 492.383856912797 -3.63575866693508 0.000310100921816092 SFPQ other 8.43090329033205e-17 1 1 1.98892857528652 -3.63575866693508 4.10180432356747e-72 119.707820454222 149.825845211928 0.798979777386848 0.424735174857857 -2148.01163489137 192.390983159047 -11.1648248770351 1.21590295576437e-25 DOCK7 other 4.01033408715192e-68 1.19632691817657e-21 1 0.798979777386848 -11.1648248770351 2.00531832947538e-41 450.594124194275 100.491902775063 4.48388488774929 9.37316825691855e-06 -501.310803703567 128.407180165338 -3.90407143166041 0.000109493198580441 SRM other 1.87898327471844e-37 0.867514612352837 0.0814996979939068 4.48388488774929 -3.90407143166041 0.19400246231425 -201.119537580401 236.768663886368 -0.849434778569024 0.396104507016917 38.3100402065656 302.656274268883 0.126579368952816 0.89933154508315 FBXO2 other 1 1 1 -0.849434778569024 0.126579368952816 6.31671510696929e-07 -20.2672064066699 22.6239640837634 -0.895829145221067 0.370836080383211 -103.90070319785 28.9066774460923 -3.59434955441049 0.000362155352210327 FBXO6 other 0.0038873064768289 1 1 -0.895829145221067 -3.59434955441049 3.24256156109054e-41 587.664588009437 93.6880043928729 6.27257023796893 8.5323430196524e-10 -242.836610608304 119.705322795154 -2.02861998896957 0.0431014995577876 MAD2L2 essential 3.03601038964907e-37 1 8.05111887334401e-06 6.27257023796893 -2.02861998896957 1.22910683487589e-05 -504.193308931775 298.787194077925 -1.68746626001742 0.0922256611439688 381.222522367615 383.694319755322 0.993557899451616 0.320986711472038 DNAJC6 other 0.0677237866016618 1 1 -1.68746626001742 0.993557899451616 0.283156693541872 -30.6710808216757 36.7231138805818 -0.835198260186039 0.404061424157385 -67.4730658754298 47.1588156352921 -1.4307625195094 0.153211323466722 LEPR other 1 1 1 -0.835198260186039 -1.4307625195094 2.55389512613109e-78 147.685224946525 124.208596593095 1.18900969012909 0.235080060290146 -1810.56563172617 158.701535436275 -11.4086207593952 1.41911210311939e-26 MFN2 essential 2.50511572922199e-74 1.39683204310041e-22 1 1.18900969012909 -11.4086207593952 1.3066684446826e-41 484.67796654051 112.559049854443 4.30598843155907 2.05333634149455e-05 -594.483028687399 143.816889725178 -4.1336106616087 4.28041053179613e-05 MIIP other 1.22500166688993e-37 0.35000916918497 0.175991457829498 4.30598843155907 -4.1336106616087 2.68967689909842e-35 29.8026772695285 33.9002359347207 0.879128904203423 0.379813427728962 -290.30983016587 43.5337532006985 -6.66861478328066 7.80137305103469e-11 SLC35D1 other 2.47988210096874e-31 7.38712014202475e-07 1 0.879128904203423 -6.66861478328066 2.35938124159957e-08 -85.3946138769529 192.011808965471 -0.444736260426092 0.656730043062262 -889.5761270659 246.576298737827 -3.60771141273292 0.000344523471451507 GADD45A other 0.000157984167937507 1 1 -0.444736260426092 -3.60771141273292 1.74510225373366e-56 225.788165303558 540.266842768189 0.417919715647692 0.676210621910207 -6701.64548989404 693.79586150614 -9.65939098475688 3.86264213013981e-20 WLS other 1.68227857259925e-52 3.78847940124113e-16 1 0.417919715647692 -9.65939098475688 4.25617985595582e-15 75.0556865556683 90.2161138874709 0.831954329680919 0.405888070056349 -434.38381794525 115.275596727862 -3.76822007671516 0.000186913336487288 PRDM2 other 3.43005534591479e-11 1 1 0.831954329680919 -3.76822007671516 3.62996369643235e-27 -61.316983939543 74.3483410280674 -0.824725650790178 0.409976273833161 -671.242863334324 95.476100385551 -7.03048051421995 7.94478927439916e-12 RPE65 other 3.24881750830695e-23 7.58806823597864e-08 1 -0.824725650790178 -7.03048051421995 2.28873237576819e-52 89.4980471488375 29.9750469037 2.98575169661503 0.00298739268287784 -261.279596210467 38.3064024244024 -6.8207813752832 3.01926013337039e-11 BCAS2 essential 2.19329223569866e-48 2.86980675676856e-07 1 2.98575169661503 -6.8207813752832 2.30047263865827e-49 536.150884291928 200.559796311172 2.67327198248686 0.00779279530750967 -1755.05837341474 257.675962858105 -6.81110629780087 3.21692372740042e-11 SRSF11 essential 2.19373070822453e-45 3.05672092577588e-07 1 2.67327198248686 -6.81110629780087 1.49821602945142e-29 37.5589113148771 14.5761683768074 2.57673418308191 0.0103009335214776 -81.7386732091325 18.7272239519446 -4.36469780138689 1.59055020804913e-05 CTH other 1.35348836100642e-25 0.133208579924115 1 2.57673418308191 -4.36469780138689 4.51130233444715e-13 1.48910220664376 4.46711374434579 0.333347725593194 0.73903133186103 -22.016442284713 5.70795149936302 -3.85715300614764 0.000131938620928613 AGMAT other 3.50122174176443e-09 1 1 0.333347725593194 -3.85715300614764 7.25912575672091e-21 -96.4417327302244 125.4661900656 -0.768667102107744 0.442505216252776 -978.663314017733 161.110812529019 -6.07447320670336 2.70295995159058e-09 OLFML3 other 6.25809231486909e-17 2.51645571493083e-05 1 -0.768667102107744 -6.07447320670336 1.82561624466753e-16 20.0272943456048 6.150602650437 3.25615154869123 0.00121724001132739 -13.2677840408668 7.9016874269484 -1.67910767966062 0.0938458627276887 TNNI3K other 1.50047399149224e-12 1 1 3.25615154869123 -1.67910767966062 7.96020013159238e-27 168.05687086752 177.140825031051 0.948719025318195 0.343286685310994 -1228.98437027006 226.345532193846 -5.42968247863422 9.37333905358754e-08 PLEKHM2 other 7.11403085760411e-23 0.000851286652846821 1 0.948719025318195 -5.42968247863422 3.28813407941698e-13 81.3904561956378 97.7380655399005 0.832740608748912 0.405444865280513 -435.987877011945 125.512543090293 -3.47365981341242 0.000564498052668845 CRYZ other 2.55948356741818e-09 1 1 0.832740608748912 -3.47365981341242 9.29353254332717e-35 110.099402669861 28.2899611105966 3.89181880595164 0.000114977971468105 -136.580686850857 36.3270664276926 -3.75974996832498 0.000193149838211271 PHTF1 other 8.55190864636966e-31 1 0.952477515641782 3.89181880595164 -3.75974996832498 7.27480502511891e-44 237.233127913024 45.2039988306367 5.24805623506568 2.40266801856322e-07 -203.158323077126 57.7844965629936 -3.51579290572608 0.00048426364710787 ZBTB17 essential 6.85941365818462e-40 1 0.00218402522887397 5.24805623506568 -3.51579290572608 7.98765806823379e-22 53.1778046557096 19.3856038127336 2.74315957188702 0.00633478607739896 -75.6864388940323 24.7752307058924 -3.05492367730128 0.0023886230419038 CD58 other 6.93728103226104e-18 1 1 2.74315957188702 -3.05492367730128 3.47600692419304e-14 -3.63947422339195 15.1350102538821 -0.240467245303545 0.810080562386051 -88.8048800348836 19.4348278078983 -4.56936798785495 6.37036466990808e-06 TFAP2E other 2.76029709850169e-10 0.0544411364690345 1 -0.240467245303545 -4.56936798785495 0.0102689016371469 2.00842385170696 12.3713494967531 0.162344767014631 0.871109230609682 -22.1848515208275 15.5468488803578 -1.42696772134039 0.154301662347211 CD2 other 1 1 1 0.162344767014631 -1.42696772134039 8.44102415467251e-22 64.8674656571377 25.8006981468805 2.51417482146624 0.0122886103923255 -99.2368301211359 32.4232659664617 -3.0606673067354 0.00234423018727459 TTF2 essential 7.3276530686712e-18 1 1 2.51417482146624 -3.0606673067354 5.92537426104155e-68 203.563097921164 39.9622745017507 5.09388167863784 5.22347216645567e-07 -344.959049350222 51.3154540846298 -6.72232284608284 5.59085830697661e-11 ADPRHL2 other 5.77783244194162e-64 5.30013367501382e-07 0.00471627301909282 5.09388167863784 -6.72232284608284 8.67193032602929e-36 235.189088874528 250.469561831252 0.938992694980562 0.348252009713389 -2145.34267241757 321.627321267358 -6.67027497528488 7.72168110595611e-11 MAP7D1 other 8.00852765608805e-32 7.31243200734044e-07 1 0.938992694980562 -6.67027497528488 1.47377251986975e-49 67.3362473757594 15.0994778595482 4.4595083354607 1.04696569978927e-05 -89.8343483068642 18.9975646429301 -4.72872970801002 3.05741759923266e-06 WARS2 other 1.40597898395574e-45 0.0264741789917556 0.0908347441137173 4.4595083354607 -4.72872970801002 1.2735837584308e-26 55.1947942441959 20.389386656716 2.70703553635418 0.00705412531962452 -99.7813186793944 26.1819590561752 -3.81107152697423 0.000158168163554654 OSCP1 other 1.13654614602365e-22 1 1 2.70703553635418 -3.81107152697423 2.23382236635205e-53 164.980590710649 33.179727398651 4.97233110834289 9.51349434704879e-07 -215.563156585955 42.606002763717 -5.05945506743305 6.1977260321875e-07 MRPS15 other 2.1446928539346e-49 0.0055035807165825 0.00853836117647629 4.97233110834289 -5.05945506743305 2.15674726004117e-71 63.5641538873739 21.2000527034591 2.9983016918162 0.0028694657653731 -248.269210091745 27.2229332454144 -9.1198552284429 2.74425632219604e-18 C1orf109 essential 2.10714207306022e-67 2.68690136506214e-14 1 2.9983016918162 -9.1198552284429 2.82744207668816e-64 106.748987375688 47.0986831118529 2.26649622288109 0.0239080106432596 -540.789012522743 60.4792980581456 -8.94172104978502 1.08248292696621e-17 RRAGC other 2.7482736985409e-60 1.05920954403644e-13 1 2.26649622288109 -8.94172104978502 1.48815832457268e-06 67.6141366785417 19.0505021044046 3.54920496625173 0.000428190888839229 -109.732472274764 41.3861042112011 -2.65143275421091 0.00830577802419803 TBCE essential 0.00889323414764636 1 1 3.54920496625173 -2.65143275421091 0.143567787807458 -252.106394367353 260.150593893522 -0.969078680906407 0.333040743813536 -1015.36896281961 523.475167826465 -1.93966977848357 0.0530615005803482 NID1 other 1 1 1 -0.969078680906407 -1.93966977848357 0.0391890825874614 99.8141941505046 67.4267918010453 1.4803343223718 0.139502973310468 -203.714785687816 135.676227471919 -1.50147737362449 0.133952676411416 LGALS8 other 1 1 1 1.4803343223718 -1.50147737362449 1.19049467374876e-15 -0.476083153398765 4.49520346011718 -0.105909144629986 0.915702925223367 26.1380259911285 5.77227922170963 4.52819847883016 7.67837853529352e-06 NT5C1A other 9.67753120290367e-12 0.0653813932280243 1 -0.105909144629986 4.52819847883016 8.21955703655713e-07 -273.133540323726 396.104875281699 -0.689548544762246 0.49084328294922 1156.46588336039 508.637253350671 2.27365548972694 0.0234699407161887 HPCAL4 other 0.00500982001378157 1 1 -0.689548544762246 2.27365548972694 0.0569742117912619 -58.3998435376942 67.5060496949469 -0.865105332064271 0.38745454441322 -325.915633878205 135.835710249532 -2.39933691427309 0.0168416974299309 MTR other 1 1 1 -0.865105332064271 -2.39933691427309 7.17102363289374e-23 10.69559803937 47.8758688210393 0.223402693314044 0.823326263179342 -340.98921881266 61.477280231889 -5.5465892037915 5.04724829269211e-08 BMP8B other 6.27249437169215e-19 0.000461066131537425 1 0.223402693314044 -5.5465892037915 0.112878679519193 -84.8270934482541 68.5590023447764 -1.23728599523177 0.216643836281196 -171.677136174373 88.0415904334973 -1.94995496252479 0.0518191236852353 MYCL other 1 1 1 -1.23728599523177 -1.94995496252479 0.0850033005082459 302.622289507396 177.281083909272 1.7070196257502 0.0885271276791872 -401.924117852569 412.45933067379 -0.974457571843481 0.33036725365589 SIPA1L2 other 1 1 1 1.7070196257502 -0.974457571843481 1.35701739352255e-42 50.842509067237 33.9257165405292 1.49864215856718 0.134686845775915 -306.575002324933 43.5664746958176 -7.03694766366682 7.62057905231646e-12 RLF other 1.2753249464325e-38 7.27917711077269e-08 1 1.49864215856718 -7.03694766366682 0.000790057421672705 80.0589199005167 21.394732075548 3.74199216974612 0.000207042049007699 17.553077257116 44.8314744129627 0.391534685998207 0.695593777513053 KMO other 1 1 1 3.74199216974612 0.391534685998207 6.56803929699447e-78 25.3150143268488 4.24171267994806 5.96811152403627 4.95934844572837e-09 -38.6385861602468 5.44709108552267 -7.09343492767007 5.28939142601769e-12 ZNF684 other 6.43996253070308e-74 5.05930289898592e-08 4.63847860128975e-05 5.96811152403627 -7.09343492767007 5.15389436107757e-06 23.0520091804132 15.1317266082373 1.52342226219342 0.128374747517799 -24.64734633073 19.431748290246 -1.26840601075005 0.205326735202457 KCNQ4 other 0.029500891322808 1 1 1.52342226219342 -1.26840601075005 0.0373539812202253 -227.600902073839 368.053601040942 -0.61839064046685 0.536639301208571 386.089974890732 472.644339797476 0.816872101030912 0.414445599721365 RIMS3 other 1 1 1 -0.61839064046685 0.816872101030912 0.604831499444266 -89.501973866013 195.921841987375 -0.456824889752622 0.648024943160775 -405.340136591532 410.543353147951 -0.987326024117741 0.324031684392172 AKT3 og 1 1 1 -0.456824889752622 -0.987326024117741 4.32066802774367e-72 138.120106894259 57.5401800703174 2.40041144684407 0.0167929906642629 -721.285997413624 73.8915210834679 -9.76141764085299 1.69502763557739e-20 ACADM other 4.22388506392221e-68 1.66350012155566e-16 1 2.40041144684407 -9.76141764085299 0.0836438014283816 -17.4035091567251 34.199266685399 -0.508885448241359 0.611088762913564 32.3298789806797 43.91776028916 0.736145895597036 0.462035971610352 ST6GALNAC5 other 1 1 1 -0.508885448241359 0.736145895597036 0.172840902878969 -21.4742650740533 118.593091728274 -0.18107517698633 0.856392326931678 -177.119062665105 153.017923731554 -1.15750533235461 0.247696784761922 ADGRL2 other 1 1 1 -0.18107517698633 -1.15750533235461 0.0901497262754085 -406.694218723602 820.066685308917 -0.495928228776178 0.620193799587014 -1635.43678611951 1047.89588344611 -1.56068633530769 0.119319991564115 PADI2 other 1 1 1 -0.495928228776178 -1.56068633530769 5.71504717015649e-54 169.139889871583 48.0179596405828 3.52242975623298 0.000472521392279619 -397.876134571448 61.3582079851146 -6.48448101137458 2.40644896370437e-10 SDHB ts 5.49387484467144e-50 2.26952201766959e-06 1 3.52242975623298 -6.48448101137458 1.55694996025506e-11 120.316582622696 21.3890356348326 5.62515228254411 3.30962785083854e-08 63.3700191587447 27.3312924352976 2.31858845712339 0.0208768987482031 MFAP2 other 1.16880233516347e-07 1 0.000305246976682839 5.62515228254411 2.31858845712339 1.18717651529218e-81 176.876998104196 24.688212743819 7.16443105621241 3.33219625887004e-12 -204.257013436376 31.8546299758996 -6.41216091949307 3.72036577547413e-10 RPF1 essential 1.16687579688069e-77 3.50309641418644e-06 3.20124094589645e-08 7.16443105621241 -6.41216091949307 1.47658395323021e-29 41.4534034676971 28.3449935233681 1.46245944397631 0.144332490479896 -198.118956479399 36.5728896508402 -5.41709879560604 1.00127536805062e-07 CTBS other 1.33409360174349e-25 0.000908256886358717 1 1.46245944397631 -5.41709879560604 1.33099265636448e-12 7.3924376830887 144.912874005806 0.0510129809639448 0.959338432207161 760.306723473388 185.172263243233 4.10594281323163 4.80484211165539e-05 IGSF21 other 1.02220236008792e-08 0.391546583678798 1 0.0510129809639448 4.10594281323163 0.0577590451090544 125.129875477835 88.5603824216665 1.41293287197032 0.158385663493322 17.2374234685945 114.267413434884 0.150851611587562 0.880162220003236 SSX2IP other 1 1 1 1.41293287197032 0.150851611587562 3.7484135962818e-71 66.7715168498584 26.3942098321425 2.5297789657088 0.0117630527193255 -326.070178391985 34.0558385669148 -9.57457493672647 7.62871045900495e-20 ZNHIT6 essential 3.66145040084806e-67 7.48071347610025e-16 1 2.5297789657088 -9.57457493672647 2.878075679236e-13 -92.2326865501549 132.516694993548 -0.696008050567859 0.486792935364971 -819.878658227059 170.983227034345 -4.7950823741464 2.23205554222793e-06 GBP3 other 2.24374779953239e-09 0.0194389717172631 1 -0.696008050567859 -4.7950823741464 2.03676869145509e-05 -121.817243177351 384.473871658665 -0.316841408889028 0.751514901462677 -1384.94424991453 496.077745447756 -2.79178871179656 0.00547108537039383 GBP1 other 0.109700361721771 1 1 -0.316841408889028 -2.79178871179656 6.16982876717177e-23 122.576986310668 310.749144548915 0.394456391790237 0.693436989137571 -2138.16160491284 397.410849835428 -5.38022956796039 1.21659379373689e-07 PINK1-AS other 5.39921715415201e-19 0.00110211231774625 1 0.394456391790237 -5.38022956796039 0.0800359110096733 -8.06749236458056 21.6623632114287 -0.372419771833771 0.709761292902866 24.3054774577081 27.8375888200652 0.873117194697151 0.383079810046535 KIF17 other 1 1 1 -0.372419771833771 0.873117194697151 3.02555561710791e-12 316.201619499145 264.233553452389 1.19667474235485 0.232082161289783 -1001.15887887294 339.41381091551 -2.94967042199164 0.00335197156431165 ECE1 other 2.3075912691682e-08 1 1 1.19667474235485 -2.94967042199164 1.07697219812592e-69 111.706221702871 35.8339688512564 3.1173276442404 0.00194546813339605 -400.026680499584 45.8067406311072 -8.73292172698111 5.31751743640327e-17 HMGCL other 1.05123256259071e-65 5.19202402490415e-13 1 3.1173276442404 -8.73292172698111 9.16258894875237e-40 41.1534129836899 19.4359542251746 2.11738577416412 0.034791384370054 -150.524494483864 24.8450769661098 -6.05852397596468 2.96705612724318e-09 GALE other 8.55052800697572e-36 2.76054902078705e-05 1 2.11738577416412 -6.05852397596468 2.27760275532848e-43 1652.23639005274 724.600840377256 2.28020214438686 0.0230765929150687 -5886.96155011619 926.260858628823 -6.35561947293214 5.22656277647692e-10 ID3 other 2.14550179551943e-39 4.9140143224436e-06 1 2.28020214438686 -6.35561947293214 3.36924997186953e-24 78.4866364630147 33.9071755129973 2.31475005734197 0.0210881802497444 -167.586075145331 43.5426648167885 -3.84877856811179 0.000136377024873848 P3H1 other 2.96830922521706e-20 1 1 2.31475005734197 -3.84877856811179 0.115942813078109 -489.069054006876 288.68431018157 -1.69413105166426 0.0909512659817307 -770.346106132739 370.720473348881 -2.07797022693099 0.0382939677028735 SLC2A1 other 1 1 1 -1.69413105166426 -2.07797022693099 5.87849635980613e-15 261.260334545404 49.6225325050538 5.26495366835208 2.20168695185344e-07 58.529074164241 64.0268061450211 0.914133902473165 0.361149427686235 CDC20 essential 4.71925687765236e-11 1 0.00200243428271071 5.26495366835208 0.914133902473165 3.31601454335306e-17 6.94988984312141 2.87939453045117 2.41366362602364 0.0162024154999525 -9.97354939966225 3.7152161751812 -2.68451388274218 0.0075390461646195 ARTN other 2.7509656651657e-13 1 1 2.41366362602364 -2.68451388274218 2.71896987334207e-21 138.504781809957 133.642236917131 1.0363847912531 0.300594490472111 -797.864105605568 172.435487749615 -4.62702959824665 4.8926602431396e-06 IPO13 essential 2.35272463140289e-17 0.0420279514885692 1 1.0363847912531 -4.62702959824665 3.08987640188644e-32 535.077544054119 128.705894192381 4.15736627612657 3.87405057578613e-05 -528.750958261246 166.066238887302 -3.18397623625398 0.00155629064683302 ATP6V0B essential 2.82013019200175e-28 1 0.328093343263327 4.15736627612657 -3.18397623625398 2.59823459777478e-41 391.557791786234 91.5197077779747 4.27839862356364 2.31339742229428e-05 -504.663264407586 118.085762506228 -4.2737011956117 2.36069782238695e-05 B4GALT2 other 2.43402617119541e-37 0.19596152623634 0.198003685374167 4.27839862356364 -4.2737011956117 1.83076966562984e-48 425.590130945104 90.5427530049194 4.70043285432221 3.48265774877438e-06 -556.596175760651 116.82522035513 -4.76434946211691 2.5810070295253e-06 ERI3 other 1.74234349077992e-44 0.0224237890725158 0.0307657985526729 4.70043285432221 -4.76434946211691 2.31925394276971e-29 54.9172165877616 31.8173149803969 1.72601668687621 0.0850496235317357 -211.420055112971 41.0531457276485 -5.14991120328651 3.94633527891741e-07 PTCH2 other 2.09382245953249e-25 0.00352920763993584 1 1.72601668687621 -5.14991120328651 3.58130637260337e-42 195.275959383536 79.0594745159157 2.46998807643509 0.0138918271579962 -625.040513731623 102.008611677412 -6.12733085426385 1.99282334499085e-09 AKR1A1 other 3.36282070091743e-38 1.85790920453497e-05 1 2.46998807643509 -6.12733085426385 8.98725214166058e-32 1279.16086789117 612.820152525725 2.08733486100145 0.0374353142002883 -4065.16678148535 790.707671026882 -5.14117534259654 4.12335868203574e-07 PRDX1 other 8.18558925062446e-28 0.00368623684989434 1 2.08733486100145 -5.14117534259654 4.85313975684095e-09 93.3878109169268 72.7509741293922 1.28366406133381 0.199938204255585 -211.035569621564 93.8688995159536 -2.2481947770752 0.0250603486546498 PIK3R3 other 3.35934333968531e-05 1 1 1.28366406133381 -2.2481947770752 0.00700747789479695 -1.01112877995211 2.72917903176861 -0.370488256058769 0.711197825507913 -7.05701654425091 3.52139659104074 -2.00403912533045 0.0456811315879095 TSPAN1 other 1 1 1 -0.370488256058769 -2.00403912533045 0.105840955083527 -6.9222209963907 62.616049208235 -0.110550267605838 0.912023622663758 83.8270491961173 80.4051080217002 1.04255875352463 0.297727790917685 FAAH other 1 1 1 -0.110550267605838 1.04255875352463 1.74022422423011e-51 87.9612523444021 20.4696619568242 4.29715217231898 2.1334242287245e-05 -144.394657301315 26.2850403629374 -5.49341584823719 6.69746517655924e-08 NSUN4 essential 1.66574262743306e-47 0.000610005128281016 0.182770453674828 4.29715217231898 -5.49341584823719 7.97497830666816e-48 136.924813604279 110.631271546783 1.23766826223612 0.216502141871949 -1131.88806347901 142.737095616098 -7.92988016600329 1.84295929862201e-14 TMED5 other 7.58021688048809e-44 1.78601185629459e-10 1 1.23766826223612 -7.92988016600329 2.66926230442235e-45 114.578224228577 69.7635893194211 1.64237857235193 0.101230919167934 -654.24332457404 90.0473706333892 -7.26554612280317 1.72081414485456e-12 DR1 essential 2.52432136129221e-41 1.65232574188935e-08 1 1.64237857235193 -7.26554612280317 7.29528858142996e-55 1251.90936488862 822.62753011534 1.52184229077902 0.12877019305148 -9061.98025722838 1061.41727842867 -8.53762270635336 2.27500874816941e-16 CNN3 other 7.01879714419376e-51 2.21836103033999e-12 1 1.52184229077902 -8.53762270635336 8.80724321608082e-09 -257.011794400558 411.252529699409 -0.624948847338185 0.532330061102009 -2043.91264096264 530.600352263361 -3.8520755446995 0.000134613059785578 F3 other 6.03208087869375e-05 1 1 -0.624948847338185 -3.8520755446995 7.70959589864448e-57 188.793004780578 92.6778302899775 2.03708917429193 0.0422418033460821 -992.584727935683 119.573463620537 -8.30104521422597 1.29328018138818e-15 ABCD3 other 7.43590524424261e-53 1.25810296045443e-11 1 2.03708917429193 -8.30104521422597 5.20065251684524e-56 109.667895734709 25.8118711900678 4.24873868799207 2.62794971981154e-05 -204.212892419713 33.3026229796981 -6.13203628267374 1.93928145029406e-09 DPH5 other 5.00978856947702e-52 1.80818602425418e-05 0.224374347077509 4.24873868799207 -6.13203628267374 1.08859938368633e-26 136.321554441513 60.9320710155351 2.23727098339981 0.0257709079421386 -337.63153246648 78.6149044933779 -4.29475218016604 2.15568673111065e-05 PTBP2 other 9.72119249631893e-23 0.179331579161095 1 2.23727098339981 -4.29475218016604 1.96787866442342e-09 16.1151873262528 40.6541185880143 0.396397410298398 0.692004920757121 199.742707766564 52.4521749678319 3.80809199788307 0.000160023444366289 PLPPR5 other 1.38538657975409e-05 1 1 0.396397410298398 3.80809199788307 0.823092246426299 -18.4288904656099 161.427084665018 -0.114162319810534 0.909161432468869 -88.6981472650092 208.274142534057 -0.425872103881092 0.670410233726105 PLPPR4 other 1 1 1 -0.114162319810534 -0.425872103881092 4.15235812213032e-07 3.72243727373893 22.9939228812525 0.161887873285594 0.871468803973848 -82.7726652979984 29.5227976137367 -2.8036863708162 0.00527670661268936 RCAN3 other 0.00258110580871621 1 1 0.161887873285594 -2.8036863708162 5.92579792610767e-66 187.851141688478 40.0258572443402 4.69324468284914 3.60125033679639e-06 -350.964626202155 51.3907648052702 -6.82933261515039 2.86101219842739e-11 SYF2 essential 5.76935686085843e-62 2.72025039826476e-07 0.0317918379732385 4.69324468284914 -6.82933261515039 1.12480170546354e-18 152.721632175205 114.948832960437 1.32860533023218 0.184677970287667 -585.068242163903 147.929905647072 -3.95503694540133 8.9381533656514e-05 RSRP1 other 9.49332639411232e-15 0.714426598516516 1 1.32860533023218 -3.95503694540133 1.02627594291279e-26 43.3805729705849 23.0037819926005 1.88580177748767 0.059983140281969 -137.37315031291 29.6796103298984 -4.62853618312246 4.85885892872333e-06 SLC35A3 other 9.16567044615417e-23 0.0417473159155908 1 1.88580177748767 -4.62853618312246 1.13893877277289e-103 243.680512675853 48.3208896365133 5.04296411984348 6.72455404536914e-07 -688.764852049777 62.0410815771502 -11.1017544269159 2.11090050876739e-25 MTFR1L other 1.12208247893585e-99 2.07649283047448e-21 0.00605815073947306 5.04296411984348 -11.1017544269159 1.01718141453248e-10 -291.114226310812 263.740600208231 -1.10378995907709 0.270290298486488 -1558.84126499048 338.626879923192 -4.60341856306284 5.45284507759109e-06 MAN1C1 other 7.48645521095903e-07 0.0467308823149557 1 -1.10378995907709 -4.60341856306284 2.1380313265735e-21 15.3344008950749 87.979335114342 0.17429548512893 0.861713962933828 -605.244526415157 113.008098537167 -5.35576241216109 1.3801544117897e-07 RPS6KA1 other 1.85132132567999e-17 0.00124862569634614 1 0.17429548512893 -5.35576241216109 4.78974789980834e-60 97.3840994217127 30.5494889853792 3.18774888405891 0.00153658770827143 -296.324162735663 39.2236846742568 -7.55472529408093 2.47114656264438e-13 DHDDS essential 4.63743391659443e-56 2.38243240104544e-09 1 3.18774888405891 -7.55472529408093 5.97184926436631e-56 10.5551922562221 166.693435819425 0.0633209832428928 0.949539926129088 -2095.92531447944 213.174575812721 -9.83196662401601 9.74459071969253e-21 ARID1A other 5.75208521143763e-52 9.56626470952216e-17 1 0.0633209832428928 -9.83196662401601 1.27173660876987e-48 470.223374836817 60.3408138849797 7.79279138881265 4.82955127146955e-14 -113.124264798777 77.5120321900365 -1.45944134868545 0.145162112989619 RPA2 essential 1.21069325154892e-44 1 4.67210790001964e-10 7.79279138881265 -1.45944134868545 8.64985104736159e-93 136.826081169359 40.6160294089944 3.36877048693142 0.000821961556187952 -591.357296853298 52.1721830776015 -11.3347240228324 2.77106083101643e-26 PPP1R8 essential 8.51318340081328e-89 2.72700096380327e-22 1 3.36877048693142 -11.3347240228324 1.26704540757469e-45 48.3338857471097 108.260872163094 0.446457568476774 0.655487905686321 -1155.16723951319 139.063471363918 -8.30676257527189 1.24713739479187e-15 STX12 other 1.19925847826945e-41 1.21346468513249e-11 1 0.446457568476774 -8.30676257527189 1.54534256803202e-14 5.0980537346118 5.43436378389371 0.938114181778065 0.348703920686908 -25.1614494869381 6.98082364869115 -3.60436687032707 0.00034894480574653 SLC5A9 other 1.23349243780315e-10 1 1 0.938114181778065 -3.60436687032707 3.44706446605596e-73 8.20541170419606 73.5584079091721 0.11154960986007 0.911231861970891 -1123.37023694812 94.5307451926836 -11.8836494376336 2.08983148249854e-28 OSBPL9 other 3.37226316714254e-69 2.05785706081631e-24 1 0.11154960986007 -11.8836494376336 2.40110531372218e-89 301.151139123232 62.3348244894024 4.83118612412923 1.88139743656955e-06 -766.341856286584 80.0734794792941 -9.5704827774438 7.95135624504795e-20 TXNDC12 other 2.36220740763988e-85 7.79630479826952e-16 0.0167538441726518 4.83118612412923 -9.5704827774438 1.69998508825737e-76 187.151382749406 40.2620610935177 4.64833090175649 4.44062975747095e-06 -316.850550751195 49.3959683158769 -6.41450226716889 3.68364124014661e-10 CD3EAP other 1.6658153879834e-72 3.46888495584606e-06 0.0390864231252593 4.64833090175649 -6.41450226716889 4.27794983937701e-09 378.843499252374 139.203460299975 2.72150920987157 0.0067587082952411 -851.091704047985 255.118423266347 -3.3360652404136 0.000922451423120221 RCN2 other 2.96633041862402e-05 1 1 2.72150920987157 -3.3360652404136 0.0752966801689611 2360.45513232709 1249.31367421338 1.88940150183926 0.0594997784200452 1063.28513943417 1442.18698513602 0.737272732588064 0.461352170819389 CTSD other 1 1 1 1.88940150183926 0.737272732588064 5.17893486804283e-06 326.723151810162 86.3898321231487 3.78196303639551 0.000177196884430633 -260.48950410709 182.133458174045 -1.430212255994 0.153369062215569 STAG1 other 0.0296390442498091 1 1 3.78196303639551 -1.430212255994 0.000659527793704823 -348.611521197723 199.86921762991 -1.74419815783355 0.0818276431301666 10.0966207706298 244.022148984984 0.0413758374501123 0.96701517217298 SLC8A2 other 1 1 1 -1.74419815783355 0.0413758374501123 5.29818990077008e-32 192.725222772513 24.4292028209506 7.88913269847799 2.46480889158222e-14 65.4764893324878 29.8258363196109 2.19529432907925 0.028667654049785 KPTN other 4.82982991354201e-28 1 2.38618148794075e-10 7.88913269847799 2.19529432907925 0.955596153505277 -3228.98169668168 18343.2902185925 -0.17603067160813 0.860351202605221 -12887.3003641042 43344.0014023038 -0.297326041601207 0.7663585628475 TTR other 1 1 1 -0.17603067160813 -0.297326041601207 0.46439025277849 7.85593903981176 34.1562354373614 0.230000143142784 0.818199033914925 -79.92432302795 80.7089621901 -0.990278165635412 0.322584913469043 B4GALT6 other 1 1 1 0.230000143142784 -0.990278165635412 0.31940632142752 -32.5472074569349 60.552887786468 -0.537500499921795 0.591196159454515 -165.866381345478 111.120939018414 -1.49266540411427 0.136248027851374 ATP10B other 1 1 1 -0.537500499921795 -1.49266540411427 0.0304827376974695 -34.883200000001 46.0835884444191 -0.756954941607319 0.449484773564036 -148.059200000001 64.0307405522622 -2.31231434656224 0.0212242820496562 ELOVL4 other 1 1 1 -0.756954941607319 -2.31231434656224 0.0662769808574523 -15.0705132743352 24.1380379311483 -0.624347070682488 0.532725483871471 -67.5814867256627 33.5385436851152 -2.01503939348613 0.0445124046887787 FILIP1 other 1 1 1 -0.624347070682488 -2.01503939348613 1.11914594997553e-10 108.466045445704 47.4490599014032 2.2859471962372 0.0227352069957345 -195.071908849153 66.6169320285156 -2.92826317437813 0.00358679653955466 CASP8AP2 other 8.22348444042021e-07 1 1 2.2859471962372 -2.92826317437813 2.02497108940664e-10 404.844318584073 99.2668407913134 4.07834393999874 5.39057415669606e-05 -124.532318584068 137.926093490253 -0.902891653295964 0.367080805723866 HMGN3 other 1.4760014270685e-06 1 0.453886343993808 4.07834393999874 -0.902891653295964 2.26104695442871e-11 11.7508359599833 8.05864889612374 1.45816452750976 0.145513492174568 -42.3006578045774 11.1173721565552 -3.80491515520916 0.000162072485214221 UBE3D other 1.68990649374001e-07 1 1 1.45816452750976 -3.80491515520916 0.200067819697039 263.608859550748 309.362559398684 0.8521033057883 0.394622421827588 -220.068531328766 437.177595062481 -0.503384742983716 0.614946851872719 CNR1 other 1 1 1 0.8521033057883 -0.503384742983716 4.63272105107578e-46 67.7436603683685 25.5297655901732 2.65351674025727 0.00825615377135134 -210.707035504055 32.800227418376 -6.42395044450236 3.47338629665236e-10 ANKRD13C other 4.38903992378919e-42 3.27158255281686e-06 1 2.65351674025727 -6.42395044450236 0.679946741460613 -55.4229412064032 74.8418195837015 -0.740534389926468 0.459372585797152 -84.4539628256435 96.1098120119886 -0.878723629332548 0.380032939717408 SGIP1 other 1 1 1 -0.740534389926468 -0.878723629332548 8.34389241942449e-11 -126.924668948419 147.611345874907 -0.859857134938539 0.390349165726836 -1214.38368936622 213.932934155272 -5.67646909608046 2.5394728543277e-08 PHF3 other 6.15528943780945e-07 0.000233123608027283 1 -0.859857134938539 -5.67646909608046 0.228690654512158 -33.8891677908752 29.7911362047596 -1.13755875432038 0.255928097456378 -5.00532985381621 37.824660690472 -0.132329801839493 0.89478434314024 PLAGL1 other 1 1 1 -1.13755875432038 -0.132329801839493 3.41955004103833e-10 76.1817368334232 87.2794483005363 0.872848514934472 0.383226096301205 -374.60045057972 111.171338054205 -3.36957760099164 0.000819776560292664 FBXO30 other 2.47541227470765e-06 1 1 0.872848514934472 -3.36957760099164 0.834031628493899 -40.227776150013 81.0871503448202 -0.496105436915045 0.620069445505352 -62.1649282156442 103.274069481204 -0.601941305575824 0.547525374479941 TNFAIP3 ts 1 1 1 -0.496105436915045 -0.601941305575824 6.76933900759749e-08 98.4665318817987 73.56489958536 1.33849882806602 0.181429827476984 -233.524292379478 94.6447451803979 -2.4673772636227 0.0139929832733587 AKAP7 other 0.000440480889224368 1 1 1.33849882806602 -2.4673772636227 0.0245909206747821 15.7097239161767 36.1362871976087 0.434735417899167 0.663970067568643 91.8649517684883 46.1816733647819 1.98920794928459 0.0473041329711302 RAB32 other 1 1 1 0.434735417899167 1.98920794928459 0.000106714934542855 27.3338803477213 6.85232252457882 3.98899500857943 7.77561547389826e-05 18.923871333224 8.72641098679095 2.16857438434527 0.0306525629344243 MYB other 0.527065061707161 1 0.650119209772633 3.98899500857943 2.16857438434527 0.0290613390518298 -2.99525671085482 6.36396073590579 -0.470659206609404 0.638118413813246 -15.9341020009486 8.10448379890407 -1.96608474966701 0.0499199887733044 ALDH8A1 other 1 1 1 -0.470659206609404 -1.96608474966701 0.0519993595898576 342.597986632579 613.489470300332 0.558441510764417 0.576828290839343 -787.110322633862 783.808906283554 -1.0042120168881 0.31583088002248 SGK1 other 1 1 1 0.558441510764417 -1.0042120168881 1.8238487556694e-36 -90.3846665643066 81.9580234452857 -1.10281657322601 0.270712395816443 -1018.42910515964 105.818717601353 -9.62428130150222 5.12193403027394e-20 RNF146 other 1.68778963849647e-32 5.02308070348965e-16 1 -1.10281657322601 -9.62428130150222 0.559719498305804 647.713516445747 622.638492667275 1.0402722030099 0.298787339419907 517.36638226334 798.179767022223 0.64818278242442 0.517206380874497 CTGF other 1 1 1 1.0402722030099 0.64818278242442 1.10417444593604e-06 131.878731778654 24.9759772490684 5.28022309051281 2.03597363546349e-07 67.6554940182635 59.6083136578683 1.13500097329683 0.256995639253348 PMFBP1 other 0.00666810947900774 1 0.00185355039772596 5.28022309051281 1.13500097329683 3.08870013679674e-08 55.6669684224862 168.700750481215 0.329974634159584 0.741577610790102 -1289.10440553609 271.185701175569 -4.75358545803825 2.71891322450498e-06 FBXL5 other 0.000205367672095615 0.0235892911358052 1 0.329974634159584 -4.75358545803825 0.000114011229202587 90.7309393242539 116.3203633257 0.780009077776043 0.435808755729559 -585.529593043286 189.373333333587 -3.09193265353711 0.00211618677762138 MED28 essential 0.561505303822741 1 1 0.780009077776043 -3.09193265353711 0.000301201201750265 28.0780788563963 38.6951312919894 0.725623041424051 0.468462791899472 -188.8214980598 63.5307262667983 -2.9721287502183 0.00312270682873555 SLC16A7 other 1 1 1 0.725623041424051 -2.9721287502183 2.73519301940363e-12 102.768775934291 23.1580706792258 4.43770888161599 1.15365984994003e-05 -102.143324440016 38.2107326780802 -2.67315796586678 0.00779670494491139 TMEM5 other 2.08749931240885e-08 1 0.0999992357928018 4.43770888161599 -2.67315796586678 2.56581789484204e-48 68.3605257766078 21.9380825626239 3.11606657425358 0.00195334258373784 -175.804880034884 28.1706354926777 -6.2407140258011 1.02909789483385e-09 DCLRE1B essential 2.44086256336323e-44 9.63647268722414e-06 1 3.11606657425358 -6.2407140258011 3.26208432506766e-08 540.004819721095 124.544262582663 4.33584661808632 1.80430265893878e-05 -289.888477278461 244.87073956556 -1.18384286253543 0.237118813115214 MYL12B other 0.000216537157497991 1 0.155061770509199 4.33584661808632 -1.18384286253543 9.02666614015626e-12 -87.7411130454244 237.988193295386 -0.36867842824674 0.712545971887677 -1590.84604369068 315.242893479337 -5.04641365942465 6.61649402210053e-07 FOXO3 other 6.80791160290585e-08 0.0058708151458098 1 -0.36867842824674 -5.04641365942465 0.84417747140972 -4.72965084620244 12.0012395051054 -0.394096863427351 0.693701323583909 -9.54623317094184 16.4587521072865 -0.580009535881863 0.562206426191798 ARMC2 other 1 1 1 -0.394096863427351 -0.580009535881863 0.152788350339406 -1.75664113857772 13.2134384771427 -0.132943528788245 0.894299095986989 -19.3769282091626 16.8870668074984 -1.14744191102262 0.251825390344041 CASQ2 other 1 1 1 -0.132943528788245 -1.14744191102262 0.000329930072724915 -38.9463552510678 37.3442176287601 -1.04290189282407 0.297569003694033 58.6505845289068 48.1817219295957 1.21727871441806 0.224153623472125 OLFM3 other 1 1 1 -1.04290189282407 1.21727871441806 0.00171890407716 60.989997572445 70.5221139936339 0.864835072555407 0.387602720237779 -203.295829100096 102.525162829762 -1.98288716144405 0.0480042754506355 PKD2 other 1 1 1 0.864835072555407 -1.98288716144405 0.757296366051158 -123.578104348918 189.540415209268 -0.65198814834545 0.514750798879596 -48.1014538359819 275.554160697808 -0.174562611263683 0.861503987687913 ABCG2 other 1 1 1 -0.65198814834545 -0.174562611263683 0.141526827564908 -4854.27403954227 5833.90126956656 -0.832080252174533 0.40581707134763 -16007.3076162305 8481.33505539923 -1.88735706249928 0.0597732455292213 SPP1 other 1 1 1 -0.832080252174533 -1.88735706249928 0.00222841793852967 -0.746091829710706 25.6398471814892 -0.0290989187427509 0.976798982325535 -98.8778881132628 37.4921849632197 -2.63729329753023 0.0086550126426259 STBD1 other 1 1 1 -0.0290989187427509 -2.63729329753023 0.00524290220713644 124.597635703805 532.096287344285 0.234163700569453 0.814967558698028 -1731.79304063368 772.427678905616 -2.24201318508847 0.0254614694519612 CCNI other 1 1 1 0.234163700569453 -2.24201318508847 0.824842548572046 -7.08369240967845 19.4914550522894 -0.36342553137645 0.71646398723136 -25.7525687769308 42.5721749033578 -0.604915507262459 0.545551279448988 RARRES1 other 1 1 1 -0.36342553137645 -0.604915507262459 0.0210807927359703 157.70856811402 106.569017882483 1.47987258630769 0.13963275939482 -373.458485250249 232.762246656349 -1.60446331230693 0.109339374149537 MFSD1 other 1 1 1 1.47987258630769 -1.60446331230693 2.93028293011722e-07 502.300367449773 175.27212698036 2.86583141371964 0.00436087485170914 -170.723534975943 203.50032911555 -0.838934933019218 0.401966601151837 KLF12 other 0.00183758042547651 1 1 2.86583141371964 -0.838934933019218 3.34948161402192e-10 20.2495527948785 15.7826828238037 1.2830234897921 0.20016857351286 -60.0516814912591 18.3489264205166 -3.272762673685 0.00115013557307704 UCHL3 other 2.42602953303608e-06 1 1 1.2830234897921 -3.272762673685 7.75804873982213e-15 678.219675740599 249.457045910226 2.71878340123003 0.00681430662313096 -783.068154523615 291.548288077458 -2.68589522403771 0.00751037371253153 PCDH17 other 6.22195508933735e-11 1 1 2.71878340123003 -2.68589522403771 0.401455421358658 -4.80086611564905 8.37217317829296 -0.573431295962264 0.566648352291162 -23.62039303768 17.4648726828344 -1.35245148743029 0.176931939822595 TRPM6 other 1 1 1 -0.573431295962264 -1.35245148743029 0.382125321057309 -75.0626334818998 183.884733459871 -0.408204814339743 0.68332370515279 -547.3184831754 397.374749785341 -1.37733583593587 0.169115089012479 GDA other 1 1 1 -0.408204814339743 -1.37733583593587 0.000413674151272167 -265.483519304826 255.453013790187 -1.03926555950864 0.299255911875182 -2169.7936605115 552.018767516505 -3.93065197814424 9.84672650796666e-05 KLF9 other 1 0.784488700889704 1 -1.03926555950864 -3.93065197814424 0.0017689557026537 -968.151367631088 651.502118175646 -1.48602950108916 0.137992377027156 -5048.75481756689 1407.85732363721 -3.58612675645525 0.000373512567164386 TJP2 other 1 1 1 -1.48602950108916 -3.58612675645525 6.4327443905334e-06 -8.53885276994003 23.8456623732506 -0.358088302865459 0.72045133046855 -184.033186446114 42.3707540461011 -4.34340125846896 1.7483875685765e-05 PIGZ other 0.0364414969723717 0.146200168484367 1 -0.358088302865459 -4.34340125846896 1.51026897290317e-12 74.5608322128251 38.658709752096 1.92869427590719 0.0544191658114976 -343.344973062732 67.7746430987619 -5.06597980254069 6.01606257560035e-07 SENP5 other 1.15807424842215e-08 0.00534406838590579 1 1.92869427590719 -5.06597980254069 0.408028584231285 111.72071796283 104.421549008071 1.06990098331327 0.285253116929459 -73.730070240377 193.877968990758 -0.380291121390341 0.703913674184568 CCDC92 other 1 1 1 1.06990098331327 -0.380291121390341 0.0135458801633492 131.325221998051 68.8030681355955 1.90871171237943 0.056952613947254 -210.47898052456 138.445571467724 -1.52030128730863 0.129156799730195 HEATR1 essential 1 1 1 1.90871171237943 -1.52030128730863 0.0379089329925298 129.939475189477 51.1311519249314 2.54129762967688 0.011388028353416 140.964214214213 105.76702466765 1.33278036946924 0.183296767356136 PTBP3 other 1 1 1 2.54129762967688 1.33278036946924 2.99730375937604e-08 541.843307593311 127.034790055244 4.26531430766076 2.44745396566795e-05 -584.146396396394 262.777020810112 -2.22297366259629 0.0267272758598804 RAD23B other 0.000199530511261663 1 0.209281788604266 4.26531430766076 -2.22297366259629 0.0464815147076481 83.434607104413 134.434504305977 0.620633873239219 0.535164086197843 -528.809876210984 271.942797856571 -1.94456290212139 0.0524688313879362 FKBP15 other 1 1 1 0.620633873239219 -1.94456290212139 7.54974921210536e-05 158.030065780068 45.7939759896614 3.45089200849791 0.000612938821093149 366.411161161159 94.7268427521309 3.86808163890711 0.000126351679786589 CTNNAL1 other 0.379903380353142 0.996156643437465 1 3.45089200849791 3.86808163890711 2.12982676135752e-05 82.3598062348068 28.5293511877498 2.88684469873859 0.00408379611072344 -134.599724724724 59.0142110480299 -2.28080190066725 0.0230396456348414 FAM206A other 0.114371697084899 1 1 2.88684469873859 -2.28080190066725 2.68539413419785e-06 496.025348956635 96.5253413110863 5.13880958325774 4.17638938380394e-07 373.374492320621 213.347467878618 1.75007698021075 0.0808068534589984 WDR34 other 0.0157417804146678 1 0.00377921475340419 5.13880958325774 1.75007698021075 2.58713918720474e-10 1392.44797161664 243.206667359632 5.72536923733927 1.92109814687957e-08 -733.252065729892 537.553412892364 -1.36405433979956 0.173252583376756 SET other 1.87929790558553e-06 1 0.000177970532326923 5.72536923733927 -1.36405433979956 1.33442046462608e-06 905.326590146949 178.59586870968 5.06913511878944 5.91240766081824e-07 215.426347501294 385.038776125377 0.55949260401541 0.576112213727584 PTPA other 0.00799851626496873 1 0.00533299171005805 5.06913511878944 0.55949260401541 1.9924410599543e-09 219.138007095842 39.9076729394074 5.49112466238168 6.78712517322896e-08 -106.311983567526 88.2068983637225 -1.2052570211589 0.228756336054574 GLE1 essential 1.40188152978384e-05 1 0.000622854477147222 5.49112466238168 -1.2052570211589 3.83793987321687e-08 551.871711458156 158.940554980717 3.47218940770094 0.000567515123053296 -1002.22091751726 325.852555121971 -3.07568838041523 0.00223169100814269 RAB14 other 0.00025341916982851 1 1 3.47218940770094 -3.07568838041523 2.10423921097754e-06 214.418656276198 42.2834195186027 5.07098665901096 5.85834015759566e-07 85.955791859418 86.044624865216 0.998967593781284 0.318363210393808 CNTRL other 0.0124381579760883 1 0.00528480865616704 5.07098665901096 0.998967593781284 0.00339178850926471 41.9789192765627 27.884476182582 1.50545841355215 0.132930351796486 -123.222818086558 56.3143296311472 -2.18812545392362 0.0291905166981343 TRIM32 other 1 1 1 1.50545841355215 -2.18812545392362 3.09100919847188e-06 280.006789542461 72.1788352784159 3.8793475741523 0.000120826969040539 -225.260692234821 147.977700870952 -1.52226106304534 0.128665287610443 FBXW2 other 0.0180174926178926 1 0.999480687903342 3.8793475741523 -1.52226106304534 0.0186836944839572 306.690184861971 122.93153366729 2.4948048373985 0.012969975805117 -62.670915841961 252.028529505316 -0.248665958433246 0.803735735635103 PHF19 other 1 1 1 2.4948048373985 -0.248665958433246 0.276354899632922 276.111218325224 204.120641034913 1.35268641586324 0.176853700931167 -138.210947426463 445.140795974504 -0.310488161670041 0.756337451464262 NEK6 other 1 1 1 1.35268641586324 -0.310488161670041 0.555668512533459 -0.0366881951920269 6.15665920305151 -0.00595910768844288 0.995248067456274 -12.3640114818803 12.4540878680712 -0.99276732369764 0.321372734033988 BSPRY other 1 1 1 -0.00595910768844288 -0.99276732369764 4.53250051505661e-12 262.690866787836 62.1850664913137 4.22434004833828 2.91818136071669e-05 -569.508557761184 136.53492716045 -4.17115656488338 3.65682745974247e-05 PPP6C other 3.44334064128851e-08 0.300518080641636 0.248658233746669 4.22434004833828 -4.17115656488338 0.000928358566144508 142.740060128115 57.7189965090678 2.47301700932535 0.0137762869173087 -193.082120262322 118.332809985706 -1.63168710593153 0.103464154002813 NDUFA8 essential 1 1 1 2.47301700932535 -1.63168710593153 0.468660057589576 6.68900251166147 22.1060608069019 0.30258681409096 0.762348737272402 54.2869124506643 44.7175675355922 1.21399520238787 0.225405220852516 HDHD3 other 1 1 1 0.30258681409096 1.21399520238787 8.83121498073124e-07 129.339056774465 37.9495743398448 3.40818201585641 0.000714439971181374 -191.2396473946 77.8024574403295 -2.45801551372938 0.0143569733316338 RBM18 other 0.00537114495128074 1 1 3.40818201585641 -2.45801551372938 2.79881958137785e-06 2.44673244672908 125.015078189794 0.0195714987516508 0.984394112459181 -1219.5055055055 258.599158457076 -4.71581389816441 3.2413890243666e-06 HSDL2 other 0.0163786921902232 0.0280315322827224 1 0.0195714987516508 -4.71581389816441 8.98107884403341e-10 851.953997229234 149.469541547946 5.69985020631075 2.2058984762689e-08 -346.527585363867 330.36643508966 -1.04891886268597 0.294793888577359 MAPKAP1 other 6.40530543156463e-06 1 0.000204111786009161 5.69985020631075 -1.04891886268597 0.905821668031056 -30.2978299379969 89.0415623933842 -0.340266153508646 0.733819603851257 -76.6500781534921 195.433790919017 -0.392204837213919 0.695098078997664 NR4A3 other 1 1 1 -0.340266153508646 -0.392204837213919 0.207293126233676 19.5242617020614 20.9314240207741 0.932772738380524 0.351451209816695 -48.6765158366341 45.9406106280068 -1.05955308758912 0.289931907602198 INVS other 1 1 1 0.932772738380524 -1.05955308758912 0.000116701810253936 -4.25769482645705 5.50041376296615 -0.774068099226239 0.439308129187836 43.9693298406465 12.0723925293647 3.64213884975131 0.000302735062075324 GALNT12 other 0.574056204639109 1 1 -0.774068099226239 3.64213884975131 0.00117260659561604 203.58717905689 63.4187592583638 3.21020438491219 0.00142400359217957 -74.7793253901663 138.301922004816 -0.540696212360393 0.588991840434443 DENND1A other 1 1 1 3.21020438491219 -0.540696212360393 0.000608030048294697 59.0126217891945 23.5342813608794 2.50751747564682 0.0125199461183565 -94.1379695722399 51.6544599991561 -1.822455787434 0.0690691022531592 ALG2 essential 1 1 1 2.50751747564682 -1.822455787434 9.83220112972257e-28 -32.034460748002 63.7845455543925 -0.502229191563096 0.615758698374856 -560.133087641693 81.9055711796888 -6.8387666378987 2.69587067967637e-11 CSF3R other 8.82636695415195e-24 2.56377301637223e-07 1 -0.502229191563096 -6.8387666378987 2.84138251186377e-10 39.4667385586419 88.1569659895686 0.447687123934278 0.654600348930603 -674.706970581299 139.12829714385 -4.84953086059621 1.72233246078579e-06 KDSR other 2.06227542711073e-06 0.0150721313643365 1 0.447687123934278 -4.84953086059621 1.54208457109416e-08 0.721457594834883 50.2436247844667 0.0143591868208109 0.988549958399989 -367.159724410086 79.2939035518138 -4.63036510959723 4.81812717203709e-06 VPS4B other 0.000104368283771653 0.0414021667893147 1 0.0143591868208109 -4.63036510959723 0.000335915625864576 68.8158179422119 21.0510168850791 3.26900207804158 0.00116435287841151 10.3907672941131 33.6298743640975 0.308974311994636 0.757487981431339 ONECUT2 other 1 1 1 3.26900207804158 0.308974311994636 1.97832884331617e-48 48.9021966608282 19.8656123941569 2.46165059956631 0.0142160822878964 -137.444919845046 24.6694110864112 -5.5714714617065 4.42893409782715e-08 ZBTB45 other 1.88257772729966e-44 0.000404893155223358 1 2.46165059956631 -5.5714714617065 3.14059444766855e-22 -175.36341773551 271.323190437308 -0.646326683144432 0.518406316211044 -1812.8211797877 305.970057891844 -5.92483196649426 6.3330527505252e-09 YLPM1 other 2.73765618003267e-18 5.86440684698633e-05 1 -0.646326683144432 -5.92483196649426 2.16673396675924e-06 -4.03159928877306 30.4727286276431 -0.132301880085521 0.894806275253626 -97.5123521373965 34.6804743553454 -2.81173640066912 0.00514876198989224 DCAF4 other 0.0128032310095803 1 1 -0.132301880085521 -2.81173640066912 9.41901912509847e-17 -4.72503869969022 7.16248261924202 -0.659692867804858 0.509797662952222 -41.4371130030957 8.07710250689086 -5.13019526095455 4.35678621161957e-07 PROX2 other 7.77728409159381e-13 0.00389061008697628 1 -0.659692867804858 -5.13019526095455 2.24299953318711e-33 73.1662242866639 50.9501557808024 1.43603534013595 0.151706086503077 -317.204578633046 57.4102505239278 -5.52522547346905 5.65627758864774e-08 FCF1 essential 2.05660627197926e-29 0.000515965641636447 1 1.43603534013595 -5.52522547346905 0.000570936679330778 17.0655683325972 415.776940828776 0.041045009130569 0.96727871679682 -916.048540468816 468.869964452481 -1.95373687785381 0.0513684784557042 PGF other 1 1 1 0.041045009130569 -1.95373687785381 2.15447268127434e-09 642.002012891068 188.542494225855 3.40507860324587 0.000722394960446791 -88.5662944520293 221.045683815995 -0.400669639520102 0.688858732573195 IFI27L2 other 1.51459429493586e-05 1 1 3.40507860324587 -0.400669639520102 1.07299015053462e-10 -77.2939671992855 47.5631593143489 -1.62508059417255 0.10486469546704 -264.754348694076 54.0831690901813 -4.8953186942986 1.3823691988872e-06 BBOF1 other 7.88862358673051e-07 0.0121344368278319 1 -1.62508059417255 -4.8953186942986 1.77824602175904e-10 170.628988947235 204.023064003464 0.836322058884177 0.403429770202967 -640.659733710546 230.266395384255 -2.78225458231303 0.0056315056718362 NEK9 other 1.29865306969063e-06 1 1 0.836322058884177 -2.78225458231303 0.00243509857011955 30.5171545709562 18.2070643117657 1.67611615186285 0.0944290406301889 -2.72963868709377 20.5490251314352 -0.132835434753451 0.894384533872254 ACYP1 other 1 1 1 1.67611615186285 -0.132835434753451 5.72429376989305e-18 116.293884523048 39.4046035738456 2.95127660160595 0.00333453809639665 -103.589169934538 45.4366565551871 -2.27985899025645 0.0230960229569461 IFT43 other 4.78665445038457e-14 1 1 2.95127660160595 -2.27985899025645 2.56116677702525e-05 -27.481092119197 97.6954261753727 -0.281293538449444 0.778618104374763 -300.30501112864 111.993721421706 -2.68144506063745 0.00760739366494397 DNAL1 other 0.136638247554297 1 1 -0.281293538449444 -2.68144506063745 1.9059956888212e-08 158.149556558927 159.441529984689 0.99189688266359 0.321795468898125 -440.794616213846 183.848824287027 -2.39759279355342 0.0169210204265019 IRF2BPL other 0.000128387869598996 1 1 0.99189688266359 -2.39759279355342 1.02029465275007e-06 -42.571587877727 57.5108590322528 -0.74023564582564 0.459553620046388 -225.692468039824 65.989317887165 -3.4201363988295 0.000684554211742476 ACOT2 other 0.00618094500635992 1 1 -0.74023564582564 -3.4201363988295 0.796393711014489 -60.9851867754393 100.795359255257 -0.60503962906664 0.545465995459515 -76.4510948905111 113.575449138744 -0.673130464992643 0.501219294202643 LTBP2 other 1 1 1 -0.60503962906664 -0.673130464992643 9.76248715295307e-23 -19.657285608332 108.798809172626 -0.180675558471809 0.856705812573535 -683.84114134041 122.593676026777 -5.57811106986502 4.26354000089536e-08 AREL1 other 8.53339002039628e-19 0.000389986003881898 1 -0.180675558471809 -5.57811106986502 1.07336278178368e-07 -126.326847922509 62.7897588894829 -2.01190210245685 0.0448421121340319 -318.961263356429 70.8663577676796 -4.50088410642009 8.68446093622584e-06 MLH3 other 0.000689850259852371 0.0737571267313661 1 -2.01190210245685 -4.50088410642009 2.02077682104661e-18 -84.6726965403135 45.6146165128833 -1.85626237845053 0.0640875015210156 -327.043204104629 51.4819899042316 -6.35257504057253 5.3116058606173e-10 TTLL5 other 1.70088785027493e-14 4.99290950898026e-06 1 -1.85626237845053 -6.35257504057253 0.0382241534609129 -29.6742309813205 102.169540397204 -0.29044107339581 0.771616288141837 -179.440436516497 115.311530587202 -1.55613610887593 0.120397964956611 FLVCR2 other 1 1 1 -0.29044107339581 -1.55613610887593 2.45786686276492e-22 287.277670278642 124.765410360405 2.30254258330731 0.021772606123855 -462.089202786372 140.697445615852 -3.28427570780509 0.00110448982304345 ABCD4 other 2.14325990433101e-18 1 1 2.30254258330731 -3.28427570780509 1.14120927497622e-31 74.6595256523692 100.16038934655 0.745399714791952 0.456429922858364 -674.354185095086 112.950463531847 -5.97035340988174 4.89674170197087e-09 DLST other 1.03872868208335e-27 4.54221760274818e-05 1 0.745399714791952 -5.97035340988174 0.0110826700074793 -55.7882609906019 70.9873862776898 -0.785889774450469 0.432357002074072 -193.541533585798 83.2250332026759 -2.32552065331679 0.0205000094809785 PPP4R4 other 1 1 1 -0.785889774450469 -2.32552065331679 0.000935754916513944 -113.295004192247 94.0337933654704 -1.20483285994766 0.228918416165324 -318.339103535549 108.428477543781 -2.93593630332963 0.00350054699424184 TGFB3 other 1 1 1 -1.20483285994766 -2.93593630332963 0.151717464079818 -27.1880769138556 15.6478540735765 -1.73749555600511 0.0830026438195932 -18.4011404413116 17.6606256288755 -1.04193027064825 0.298018767776146 ZC2HC1C other 1 1 1 -1.73749555600511 -1.04193027064825 3.12803930551702e-18 115.356100749154 48.8329986276929 2.3622571619785 0.0186004885992552 -165.798210043993 56.3669220949951 -2.9414096757771 0.00344046855591666 SLIRP other 2.62536338912044e-14 1 1 2.3622571619785 -2.9414096757771 3.38700656340286e-14 -29.4750076529429 224.245813973777 -0.13144061479065 0.895487114164783 -1138.07967085027 257.304942965342 -4.42307737167554 1.22910495755212e-05 RBM25 essential 2.68996061265455e-10 0.103613547921644 1 -0.13144061479065 -4.42307737167554 1.02060081562283e-15 -631.338290354939 490.614275666403 -1.28683228692722 0.198832425551971 -3085.90580905677 557.868215892843 -5.53160356002344 5.46733922488554e-08 ALDH6A1 other 8.3005464334605e-12 0.000498840030878556 1 -1.28683228692722 -5.53160356002344 0.936920201808316 3.06755845982541 15.7284932845612 0.195031933722251 0.845458797991939 6.13234777002885 18.4394910088263 0.332566000172864 0.739621748395519 GPR68 other 1 1 1 0.195031933722251 0.332566000172864 0.411229210529224 3.10635295097937 5.72934755610597 0.542182669241075 0.587968400623157 -1.3199962504101 6.60639553711623 -0.199805815893714 0.841725182152419 ESRRB other 1 1 1 0.542182669241075 -0.199805815893714 4.51564302652627e-26 57.0783883574313 59.739015057137 0.955462494700307 0.339870896427311 -343.216124417591 67.4231990789977 -5.09047522374984 5.31284275826413e-07 EIF2B2 essential 4.01982542221368e-22 0.00472789877057925 1 0.955462494700307 -5.09047522374984 1.39918405508612e-19 -11.9861396003052 59.8363114678551 -0.200315482459916 0.84132725586263 -399.997245501966 70.1498298248231 -5.70204156590018 2.18548694393922e-08 NRDE2 essential 1.19028587566176e-15 0.000200802540409135 1 -0.200315482459916 -5.70204156590018 2.39893708925612e-32 5.04875712196835 30.0063106681124 0.168256510365789 0.866459151148331 -232.703664887525 34.397909189989 -6.7650525967215 4.28273887629542e-11 COQ6 other 2.19166892474439e-28 4.06517574137961e-07 1 0.168256510365789 -6.7650525967215 6.79324876152651e-31 271.894292341049 70.0322967905032 3.88241289807191 0.000119363787289328 -248.960498735874 80.2819317579779 -3.10107758102287 0.00205270688004399 ZNF410 other 6.16487325108531e-27 1 0.987974067393768 3.88241289807191 -3.10107758102287 0.000776793896544014 -53.6551197521258 45.228314715578 -1.18631702484473 0.236143171774502 -214.727551065357 63.3239386211516 -3.39093802029607 0.000759995343722343 SLC17A5 other 1 1 1 -1.18631702484473 -3.39093802029607 0.418825192621496 -1820.9444144844 1539.4024781844 -1.18289040084699 0.237500174172297 -2731.37610830012 2191.57941778455 -1.24630487315912 0.213324776368327 OGFRL1 other 1 1 1 -1.18289040084699 -1.24630487315912 9.8955303277483e-11 72.1004181471659 119.016366647543 0.605802547818364 0.544959669603867 -487.131310776192 143.526161364736 -3.39402451890474 0.000751405724609539 SLF2 other 7.28607898032107e-07 1 1 0.605802547818364 -3.39402451890474 0.0738193020014777 68.852401807163 36.7073844533668 1.87570982875757 0.0613600573140953 35.8797140399759 44.3255006722917 0.809459870633897 0.418690184833787 IDE other 1 1 1 1.87570982875757 0.809459870633897 0.389732347762678 -655.533962929204 666.100841171002 -0.984136218439206 0.325593089167482 -1090.92602320075 805.546475827521 -1.35426825879918 0.176350652101269 IFIT3 other 1 1 1 -0.984136218439206 -1.35426825879918 0.140595688151983 -62.4856600010237 359.262759795515 -0.173927461996309 0.862003010364824 -548.665437278254 434.473028949457 -1.26282968267308 0.207323803572759 IFIT2 other 1 1 1 -0.173927461996309 -1.26282968267308 6.84327502473402e-06 -118.712135922342 120.637008932229 -0.984044092049995 0.325638330459088 -454.411429832317 138.07101227094 -3.2911428862462 0.00107870549529668 GPAM other 0.038643974064673 1 1 -0.984044092049995 -3.2911428862462 5.07043666754203e-36 55.5131342887644 25.4508754594611 2.18118761286571 0.0297007023376889 -183.196347669476 30.6921355521302 -5.96883678420877 4.93900984668668e-09 CUTC other 4.68559052447559e-32 4.58093163280189e-05 1 2.18118761286571 -5.96883678420877 0.0018283603223712 -179.820410665028 134.436341135808 -1.33758780658403 0.181724965559815 -482.810603738888 162.336767332632 -2.97412971609565 0.00310053933090153 PPP1R3C other 1 1 1 -1.33758780658403 -2.97412971609565 7.19797614127198e-06 -90.6475556889678 60.5434696405926 -1.49723093550937 0.135053438712457 -283.02067559738 73.0115700721241 -3.87638117243335 0.000122259075307528 CNNM1 other 0.0405461996037851 0.965113140477628 1 -1.49723093550937 -3.87638117243335 3.59963084236458e-38 189.461079400609 237.510589531723 0.79769529339366 0.4254805671157 -2013.69848156182 282.95346682248 -7.11671252582736 4.56125320660617e-12 MXI1 other 3.34549690489364e-34 4.36557544404276e-08 1 0.79769529339366 -7.11671252582736 7.83529092666804e-13 107.625618521147 32.7388041092447 3.28740225702856 0.00109278397272022 -37.7787418655102 39.0027162182408 -0.968618227872085 0.333271476412731 SMNDC1 essential 6.04962812448039e-09 1 1 3.28740225702856 -0.968618227872085 4.81561584839607e-37 32.1340835594208 12.4133372588889 2.58867401160879 0.00995512495703063 -72.4221065682318 14.4105439985837 -5.02563307640223 7.3248176160213e-07 C10orf88 other 4.46311276829348e-33 0.00649125337131807 1 2.58867401160879 -5.02563307640223 1.49605178393238e-15 219.217194736825 29.3967678073173 7.45718700007076 4.81435279453106e-13 317.434142769274 37.2806647130097 8.5147125249218 2.72719552510142e-16 HELLS other 1.21359720712595e-11 2.65847019786886e-12 4.64055465864849e-09 7.45718700007076 8.5147125249218 5.5631262040202e-09 -212.95594635303 219.595207227527 -0.969765911750442 0.332699612210578 -970.458343291622 248.959967276059 -3.89804977044977 0.000112193563006574 PRLHR other 3.84300758173716e-05 0.887563276945005 1 -0.969765911750442 -3.89804977044977 9.05666196252279e-06 263.837233952672 57.2958101022914 4.6048259633931 5.41779471716564e-06 192.668826829619 72.5159523245117 2.65691645291258 0.00817402792933015 TCTN3 other 0.0506176837085399 1 0.0475194774642598 4.6048259633931 2.65691645291258 1.01129528458203e-67 58.7562098078549 20.8781051186453 2.81425011867491 0.00510989942664701 -185.461411373024 23.6699718210995 -7.83530342895055 3.59188985183024e-14 FAM45A other 9.8591177293902e-64 3.47694937657167e-10 1 2.81425011867491 -7.83530342895055 4.94297384919801e-11 -11.9603772399507 25.1941894713035 -0.474727605489103 0.635217746500551 -132.347578725455 30.3825885915389 -4.3560336646994 1.65124374956143e-05 AVPI1 other 3.66867519087476e-07 0.138192589400796 1 -0.474727605489103 -4.3560336646994 0.00500596983612109 87.3823428914662 98.9238129040926 0.883329709260034 0.377544946414992 -101.68661977319 115.022666568691 -0.884057228080895 0.377152550013807 WDR11 other 1 1 1 0.883329709260034 -0.884057228080895 2.11356951857345e-28 56.2312795855239 38.24177991637 1.47041481093439 0.14216742452964 -254.43189583411 46.0578066912468 -5.52418610681398 5.68766244409268e-08 C10orf76 other 1.90178985281239e-24 0.000518771691525693 1 1.47041481093439 -5.52418610681398 6.18137217599969e-09 -535.847180289987 487.88077257058 -1.09831583947586 0.272669978853686 -2565.90289115012 587.596036601136 -4.3667804602499 1.57531518895416e-05 KCNIP2 other 4.26329238978699e-05 0.13196415337869 1 -1.09831583947586 -4.3667804602499 0.0598679758610442 0.651717110570438 9.40726043858205 0.0692780979994502 0.944799875653219 15.1693589034912 11.239107801871 1.34969422581443 0.177811232642 CFAP58 other 1 1 1 0.0692780979994502 1.34969422581443 0.00638582635273382 -288.802619178931 281.348488137696 -1.02649429926059 0.305225200705225 -864.742774570517 339.288365504889 -2.54869563028991 0.0111528173406007 GOT1 other 1 1 1 -1.02649429926059 -2.54869563028991 2.30846536833514e-10 -2.00165607443448 2.37765246493929 -0.84186234277329 0.400324424863782 -12.7891406297997 2.86002813989144 -4.47168349549356 9.8994551465956e-06 C10orf95 other 1.67871601585332e-06 0.0839077818225443 1 -0.84186234277329 -4.47168349549356 0.511557712876318 160.09256479885 149.584287177043 1.07024987597374 0.285096263294373 204.759250546245 180.389127510343 1.13509751597698 0.256955235137717 SFRP5 other 1 1 1 1.07024987597374 1.13509751597698 8.76924470360207e-05 317.007237490467 88.0839609416642 3.59892123493871 0.000356202885577596 -388.894559173064 206.246623932282 -1.88558024251952 0.0600161237584504 KANSL1 essential 0.437322233368635 1 1 3.59892123493871 -1.88558024251952 0.132705912350305 -22.5483622873691 13.8425308699179 -1.62891905383938 0.104050782831822 -45.805917480999 32.1421894811067 -1.42510259009966 0.154841353096149 CRHR1 other 1 1 1 -1.62891905383938 -1.42510259009966 0.0023902310216324 128.096126636011 61.7069590699279 2.07587812730893 0.0384894098073126 440.241695340388 139.345537659499 3.15935266198585 0.00169098707681088 HOXB3 other 1 1 1 2.07587812730893 3.15935266198585 0.462657754376248 561.281439547112 457.854321362285 1.22589525392508 0.220898303741413 665.363040841088 858.072468954014 0.775415905899139 0.438513340428853 DUSP1 other 1 1 1 1.22589525392508 0.775415905899139 0.000164274076747294 92.037997945867 164.889842512347 0.558178700055312 0.577008217439906 -964.29142396008 294.018978606524 -3.2796910884129 0.00112234588206998 PANK3 other 0.792622420305694 1 1 0.558178700055312 -3.2796910884129 0.00170194762818568 122.02566735113 38.1775085327585 3.19627110413517 0.00149292534761671 3.75154004106796 73.2154505655959 0.0512397316698453 0.959157851259739 MSX2 other 1 1 1 3.19627110413517 0.0512397316698453 0.171008238841638 -97.0700495541667 59.0553379681061 -1.64371338635961 0.100983731673053 -120.877861622837 67.41693356681 -1.79298961295899 0.07369400350637 TEK other 1 1 1 -1.64371338635961 -1.79298961295899 2.46784970076466e-17 111.258874492977 18.4932901859726 6.01617523837742 3.78606543287266e-09 -19.4472476980182 21.2929681839349 -0.913317839487062 0.361580161177586 RCL1 other 2.04979596145513e-13 1 3.54640749097182e-05 6.01617523837742 -0.913317839487062 2.65411236482181e-09 89.4058121860095 19.9843680031024 4.47378732077642 9.9242318227675e-06 -9.34590493366024 22.5033273004034 -0.415312136240969 0.678127027566694 CAAP1 other 1.86053276774009e-05 1 0.0862118018443813 4.47378732077642 -0.415312136240969 5.40607636890246e-07 163.056532689109 167.07699113864 0.975936492379166 0.329656369845422 -623.581242286066 190.68287837558 -3.27025293302855 0.00116284484953904 MOB3B other 0.00333987398070794 1 1 0.975936492379166 -3.27025293302855 0.556326525151873 -18.9016491115111 20.1490673506006 -0.938090522137626 0.348716064572319 -5.75816870179501 23.2000761951388 -0.248196111657665 0.804099261152613 CD274 other 1 1 1 -0.938090522137626 -0.248196111657665 0.0331904141052854 -466.941063643749 728.006432841986 -0.641396892361112 0.521601873001494 -2209.3333623266 993.472352072047 -2.22384987133128 0.0266701346080391 GRIA2 other 1 1 1 -0.641396892361112 -2.22384987133128 5.53569150489172e-19 137.634794563776 55.5584372103969 2.47729780523812 0.0136153116035586 -258.985559737649 70.7602361204466 -3.66004374684122 0.000283005513835096 NUP43 essential 4.68596285889084e-15 1 1 2.47729780523812 -3.66004374684122 3.1830470677126e-08 249.687250427839 62.4454521152384 3.99848574988392 7.48094958454136e-05 20.7694428598599 82.3196553758274 0.252302354340986 0.800925720464536 MTHFD1L other 0.000211354325296116 1 0.626080670730267 3.99848574988392 0.252302354340986 1.00179449918598e-08 -135.21290089928 83.2380743105061 -1.62441168923359 0.105008983034261 -521.008929658096 106.013525364613 -4.91455149582269 1.26073966266895e-06 LRP11 other 6.84025284044185e-05 0.0110831623745228 1 -1.62441168923359 -4.91455149582269 0.448589590592539 -44.0533371363376 41.1748184040805 -1.06990968858704 0.285249202538474 -21.4320846802302 54.2793229350173 -0.394848047494781 0.693147237243006 CCDC170 other 1 1 1 -1.06990968858704 -0.394848047494781 6.03309806793712e-17 21.7928553719909 188.695619405181 0.115492110737323 0.908108123102215 -1290.71507809506 240.326172844651 -5.37068044989589 1.27721737010288e-07 PCMT1 other 4.99480189044515e-13 0.00115613716341713 1 0.115492110737323 -5.37068044989589 0.282931435560531 -164.894680547634 105.403062372173 -1.56442020598415 0.118441098217547 -193.621553527287 138.949170453948 -1.39347038125326 0.164184274580688 PLEKHG1 other 1 1 1 -1.56442020598415 -1.39347038125326 0.103253706824894 -14.6650028522529 23.1533672456855 -0.633385316988208 0.526812631423561 -54.4907301768389 30.5222742072147 -1.78527752574736 0.0749081593836587 MYCT1 other 1 1 1 -0.633385316988208 -1.78527752574736 0.211778340322516 -7.52016025601814 117.274920303106 -0.0641241983928168 0.948900790146728 -414.908231442914 247.9236993518 -1.67353194764235 0.0949415026706271 CYSTM1 other 1 1 1 -0.0641241983928168 -1.67353194764235 8.78528850342921e-05 122.290704263111 44.8913488047394 2.72414858361753 0.00670584187632627 -212.345636663842 94.9003290940201 -2.23756480816274 0.0257538786494723 WDR55 essential 0.43803448478098 1 1 2.72414858361753 -2.23756480816274 0.556059390465306 21.8770949101648 109.264994511872 0.200220528156323 0.84140146834091 -203.237577355858 223.134752002053 -0.910828884933118 0.362888819307501 ARAP3 other 1 1 1 0.200220528156323 -0.910828884933118 0.034132633619315 98.181622965643 37.8947329389074 2.590904206237 0.00989256638292159 98.8515124116409 79.8941902195271 1.23728035968603 0.21664744172407 PCDHB8 other 1 1 1 2.590904206237 1.23728035968603 0.350078237176064 125.349909584091 88.307471632006 1.41947116441571 0.156474608529729 148.774289002142 186.180331386613 0.799087035102565 0.424674040411108 PCDHB10 other 1 1 1 1.41947116441571 0.799087035102565 0.27653709587993 60.3409810126592 59.4627795060623 1.01476892795614 0.310777488750663 -98.4237629459146 125.366515301694 -0.785088129067465 0.432827309844074 PCDHB14 other 1 1 1 1.01476892795614 -0.785088129067465 0.38148488780918 0.457504520796038 9.97201329424287 0.0458788518723866 0.963427767832154 -26.8114417228342 21.0241863502855 -1.27526655615236 0.202892447853507 PCDHB12 other 1 1 1 0.0458788518723866 -1.27526655615236 7.30476245798966e-08 -174.093123189682 233.031895110154 -0.747078519476438 0.455417015256251 -1296.95541020166 306.105074070537 -4.23696148827248 2.76383946991239e-05 ACAT2 other 0.000474809559769328 0.228873546503445 1 -0.747078519476438 -4.23696148827248 1.98327620806404e-35 489.762924009107 205.140980212513 2.38744556792965 0.0173890764059022 -1828.20613724091 269.468241303066 -6.784495747626 3.79194395948407e-11 TCP1 essential 1.82957230193907e-31 3.60082998392607e-07 1 2.38744556792965 -6.784495747626 1.01752961975671e-08 54.9436486940762 21.6113602312967 2.54235032436825 0.0113558761342108 -57.8583142109652 28.7589315401362 -2.01183810080766 0.0448516984157579 SLC10A7 other 6.94260459560005e-05 1 1 2.54235032436825 -2.01183810080766 3.12221379917827e-07 79.8400378608611 14.7034404292245 5.43002423447584 9.36694745685983e-08 61.4504323882457 28.6077302578585 2.14803592715522 0.0322600152635598 MASTL essential 0.00195513028104543 1 0.000857356700726381 5.43002423447584 2.14803592715522 0.219621100798546 -62.3769144144146 37.6801157868153 -1.65543319365916 0.0985578637221073 -104.019817473725 74.282689572879 -1.40032379107209 0.162129229344417 KIAA1217 other 1 1 1 -1.65543319365916 -1.40032379107209 0.0205636133372548 273.519206195357 156.985624323158 1.74232008424104 0.0821543463228354 879.801565346629 314.978983167239 2.79320720544551 0.00544757491346667 PLXDC2 other 1 1 1 1.74232008424104 2.79320720544551 1.26109923207015e-29 223.291307773825 48.9480275405967 4.56180399891764 6.60113211692064e-06 -624.75411942349 92.6499687990708 -6.74316599909914 4.93441915821673e-11 EPC1 other 1.13965537602179e-25 4.68227033923186e-07 0.0577136980982372 4.56180399891764 -6.74316599909914 2.1227938751827e-72 85.0530178433166 18.1990578899574 4.67348465824985 3.94761703322487e-06 -178.831771380432 23.3682005806495 -7.65278313848939 1.26495953582655e-13 TAF12 other 2.07566785115364e-68 1.22093894397979e-09 0.0348100869989769 4.67348465824985 -7.65278313848939 5.5613891175613e-06 -2.79665313090063 26.6471175581975 -0.104951431418153 0.916462501328102 -103.16337066446 31.9419038326635 -3.22971890482513 0.00133263118684762 ENOX1 other 0.0317110407483346 1 1 -0.104951431418153 -3.22971890482513 2.97353715718195e-18 58.6343889805318 10.6873751897658 5.48632268816387 6.95386469849124e-08 -8.59609589589039 12.9233373742782 -0.665160681558891 0.50629781132725 MTRF1 other 2.49658179716996e-14 1 0.000638086624733556 5.48632268816387 -0.665160681558891 0.00112555146047878 28.1287350597618 12.8154866159053 2.19490183266636 0.0286960043822227 -3.01472407074919 15.2860288085713 -0.197220881139433 0.843746386511595 SOHLH2 other 1 1 1 2.19490183266636 -0.197220881139433 0.000143593330193875 38.8107363629351 111.081530411393 0.349389643977703 0.726965107207776 -319.941075446806 133.153447243838 -2.40279979279028 0.0166861290576654 DNAJC15 other 0.698150771402622 1 1 0.349389643977703 -2.40279979279028 3.07792026558927e-16 212.284115786915 68.0496713023913 3.11954652717706 0.0019309163593445 -238.60919407088 82.4061095247407 -2.89552795838812 0.00397458724692581 PROSER1 other 2.52327903373009e-12 1 1 3.11954652717706 -2.89552795838812 2.84583957034673e-21 256.35052298711 85.3911239268271 3.0020745857237 0.00283485637508328 -414.333244527842 103.406088171767 -4.00685541686479 7.22991222038649e-05 UFM1 other 2.46165122834992e-17 0.581284942519074 1 3.0020745857237 -4.00685541686479 1.30388170016016e-40 146.203859404505 25.8748376224274 5.65042616065656 2.88652325465499e-08 -143.939678391424 31.2882490005129 -4.60043891842796 5.52777129992818e-06 WBP4 other 1.21925977781977e-36 0.0473674722690846 0.000266454961637202 5.65042616065656 -4.60043891842796 0.00707148577408437 34.6338010283444 77.2532873027162 0.448314916265404 0.654147622175962 -154.708338889037 93.4158553768264 -1.65612505783912 0.0984126817654375 ELF1 other 1 1 1 0.448314916265404 -1.65612505783912 6.07986033997217e-10 -14.4039752338196 219.755243117762 -0.0655455361586111 0.947769625717697 -1137.62220669836 264.147573413938 -4.30676758448061 2.04737738994148e-05 SMAD9 other 4.36777166823601e-06 0.170444167712628 1 -0.0655455361586111 -4.30676758448061 0.0210482692529968 -329.052422872681 463.560255677971 -0.709837435030818 0.478187032459771 -1300.51595828773 562.776158214437 -2.31089384172559 0.0213076940117965 HSPH1 other 1 1 1 -0.709837435030818 -2.31089384172559 4.38793708380639e-18 80.3793510684084 42.5178318369177 1.89048565262484 0.0593528755053759 -226.402890743754 51.4132118967328 -4.4035935976632 1.33973820852443e-05 KBTBD7 other 3.67358092656271e-14 0.11268538071899 1 1.89048565262484 -4.4035935976632 4.16607062768521e-15 71.2523566926376 29.1753528447612 2.44221062455571 0.0149929997715145 -115.028195313972 35.0690092673207 -3.28005260819163 0.00112094352871337 ALG5 other 3.35785292591428e-11 1 1 2.44221062455571 -3.28005260819163 6.56366583342744e-16 211.994487105596 49.1997651198153 4.30885160913531 2.02896427997403e-05 -88.9937792345401 59.1385142149744 -1.50483623770186 0.133088582336404 EXOSC8 essential 5.35201312057673e-12 1 0.173943107722173 4.30885160913531 -1.50483623770186 1.89583670049639e-08 22.2385884111823 139.882497715733 0.158980492730228 0.873757857208803 -1674.34672421693 302.40705636516 -5.53673166341441 5.3326508054907e-08 SERP1 other 0.000127722518512442 0.000486657712509081 1 0.158980492730228 -5.53673166341441 5.06673289408445e-05 -2.92428008629552 15.2017666302808 -0.19236449008963 0.847545861267299 134.997443954601 33.2005942385063 4.06611529253986 5.66812202445617e-05 PLS1 other 0.260328736098059 0.458947840320216 1 -0.19236449008963 4.06611529253986 7.59241412877663e-44 106.716075343419 26.0342738902814 4.0990609453201 4.94641486964075e-05 -165.037520251757 34.7016620394271 -4.75589670789385 2.68767132763974e-06 ZFP30 other 7.1581280406106e-40 0.0233236117812576 0.417081701808108 4.0990609453201 -4.75589670789385 0.00126126638564175 43.9560723514219 32.4049703055746 1.35646081255196 0.175651360318644 -108.715645379599 53.7364561490777 -2.02312644283791 0.0436670396220412 NR2C1 other 1 1 1 1.35646081255196 -2.02312644283791 8.37606526551988e-05 119.928776222415 45.3134056105205 2.64665113130608 0.00842356654758065 -116.977231743231 78.779625083595 -1.48486657075486 0.138301788113472 UTP20 essential 0.418803263275994 1 1 2.64665113130608 -1.48486657075486 0.00193096909258568 357.002290669083 175.824775147654 2.03044360710417 0.042916526467159 -411.768927138597 305.664824571908 -1.34712565541452 0.178637879383208 TMPO other 1 1 1 2.03044360710417 -1.34712565541452 0.000579503510842023 136.440565549371 76.1883204025259 1.79083309395081 0.0740120759393076 -254.871198395236 132.450558066743 -1.92427425082501 0.0549692524076984 ARL1 other 1 1 1 1.79083309395081 -1.92427425082501 0.0082146721180415 -0.102287353105691 7.05029567182264 -0.0145082359473936 0.988431144965396 -32.5760982092893 12.3471515446361 -2.63834926553899 0.00862922218088042 GLT8D2 other 1 1 1 -0.0145082359473936 -2.63834926553899 0.000154681340856649 56.9037328723273 39.596442212948 1.43709206413802 0.151405786465947 -165.080420028172 67.0810581854526 -2.46090959942507 0.014243289357129 MTERF2 other 0.749431096450463 1 1 1.43709206413802 -2.46090959942507 0.472558322724893 41.8145055141659 172.696159812954 0.242127593106036 0.808794624770817 -224.513341341546 274.98706602648 -0.816450550150334 0.414686312240473 SOCS2 other 1 1 1 0.242127593106036 -0.816450550150334 2.31869476925885e-09 87.4053413290555 44.0498398299327 1.98423743801361 0.0478559162549796 -307.121695704294 75.8971412979158 -4.04655156244637 6.14894453184925e-05 NFYB essential 1.62795559749664e-05 0.497019186509375 1 1.98423743801361 -4.04655156244637 0.0108434909997844 76.9670473663787 33.5010454340035 2.29745210542765 0.0220647725233227 -23.124967645914 58.2403200399986 -0.397061136168758 0.691516225258151 WASHC3 other 1 1 1 2.29745210542765 -0.397061136168758 0.0183513273972066 35.7822052543027 48.3444842911188 0.740150728236771 0.459605993106596 -159.41652646564 84.045085781879 -1.89679771259168 0.0585137585947894 APAF1 other 1 1 1 0.740150728236771 -1.89679771259168 1.42865764472929e-65 72.6706843915801 32.4181813678098 2.24166444030509 0.0254841993052537 -371.961167662299 41.4394617526883 -8.97601348883759 8.38117018337508e-18 UBIAD1 other 1.39065535137949e-61 8.20348937548753e-14 1 2.24166444030509 -8.97601348883759 8.74819010180333e-31 457.22160863024 113.151243545441 4.0408005630678 6.29140538674283e-05 -426.713994789564 144.583112814508 -2.95134048840832 0.00333386203272871 TARDBP other 7.93810769837634e-27 1 0.528037654109326 4.0408005630678 -2.95134048840832 6.6585645191054e-07 -12.0882632878065 15.9114981661915 -0.759718736824636 0.447831427900468 -70.8386519664307 20.3301483096094 -3.48441392987515 0.00054288356816071 TNFRSF8 other 0.00408636104537498 1 1 -0.759718736824636 -3.48441392987515 0.00468121784894796 187.372071944363 69.1422728940005 2.70994955910137 0.00699348032985558 -235.575937214066 164.539856464256 -1.43172567593215 0.152935522745805 SPOP other 1 1 1 2.70994955910137 -1.43172567593215 6.34841242514797e-09 302.922170530649 48.2466104607523 6.27862077020045 8.2332822651532e-10 105.157776718172 114.813847272121 0.915898031610568 0.3602243590587 SLC35B1 essential 4.37659552589701e-05 1 7.7713951300781e-06 6.27862077020045 0.915898031610568 8.38941625109936e-05 -11.5889402940834 18.1632531646737 -0.638043206743554 0.523778984308133 180.721999561838 43.2236162270952 4.1810939328244 3.50501514890643e-05 FAM117A other 0.419339456173275 0.288392646452021 1 -0.638043206743554 4.1810939328244 0.0706289842212515 -12.1277133159682 61.3323740900379 -0.197737548821514 0.843342565496905 -136.736581419212 79.9640576053803 -1.70997552542921 0.0879818496242127 LRAT other 1 1 1 -0.197737548821514 -1.70997552542921 4.14739646994194e-05 38.8185234305924 8.54821826058113 4.54112450656511 7.25052025517745e-06 36.4127615679341 11.2908135395831 3.2249900718207 0.00135453473914557 MND1 other 0.215830512295778 1 0.063333294428975 4.54112450656511 3.2249900718207 0.00875459162605932 -12.871106499511 9.03704723319883 -1.42426017784075 0.155083215624365 -30.9788537692174 10.7234534071867 -2.88888780441345 0.00405785703424579 TRIM6 other 1 1 1 -1.42426017784075 -2.88888780441345 0.0897098543276101 25.4521858155789 24.2786781446419 1.04833490785395 0.295062452147543 -94.1821427964143 59.6036067335273 -1.58014167192061 0.114796276977613 PAPD5 other 1 1 1 1.04833490785395 -1.58014167192061 0.276090603856106 21.2378976722058 84.2765426433382 0.252002479053816 0.80115735106372 -301.920924656947 206.897009575599 -1.45928123986068 0.145204499482126 ADCY7 other 1 1 1 0.252002479053816 -1.45928123986068 1.0274947455608e-74 323.818694366727 35.6109315903531 9.09323850585387 3.39722597357786e-18 -142.244339487922 46.0512176240393 -3.08882906526383 0.00213763402747801 CEP89 other 1.00602010537858e-70 1 3.31263504683577e-14 9.09323850585387 -3.08882906526383 2.32191708178139e-08 9.35829508007986 34.6536067892401 0.270052555769912 0.787247889643775 -126.051274708723 44.1771957217094 -2.85331091413708 0.00453311165314043 TSHZ3 other 0.000155522006137717 1 1 0.270052555769912 -2.85331091413708 1.75706869981353e-07 101.96158003341 72.2741108140199 1.41076215099739 0.159026211696051 -162.45735481969 92.8411939322063 -1.74984129284591 0.0808475772608513 ECHDC2 other 0.00111714427934144 1 1 1.41076215099739 -1.74984129284591 1.89993790630366e-12 146.393941595234 56.8306601506381 2.57596764153706 0.0103319597324838 -193.809983880229 70.7335901021725 -2.73999925071351 0.00640210261747042 PSPC1 other 1.45459246106608e-08 1 1 2.57596764153706 -2.73999925071351 1.43271654535824e-45 47.7125054808116 19.5321247764217 2.44277087244538 0.0149700677795422 -126.127985599888 24.4983593514286 -5.14842581050365 3.97953690026644e-07 ZNF549 other 1.3557796668725e-41 0.00355850189621825 1 2.44277087244538 -5.14842581050365 1.29348547126007e-30 69.2440530586252 18.6994052401248 3.70300831333624 0.00024039780212242 -53.8955166015895 23.3457510636952 -2.308579255152 0.0214339053146409 A1BG other 1.17332067098001e-26 1 1 3.70300831333624 -2.308579255152 1.53898784201309e-46 413.509981250693 179.631609838081 2.30198895185223 0.0218051758913629 -1221.45760036395 224.23555284553 -5.44720756750548 8.55813914926319e-08 ZSCAN18 other 1.45972996814941e-42 0.000778106011451009 1 2.30198895185223 -5.44720756750548 2.00588716456553e-47 154.230609466227 28.7093994790164 5.37212941632422 1.26762594319076e-07 -86.8319987076825 36.0090462892031 -2.41139401500112 0.0163031843605778 ZNF211 other 1.90499104018788e-43 1 0.00115797629910476 5.37212941632422 -2.41139401500112 0.303746021177102 193.844748858452 137.460174156813 1.41018844219793 0.159195402068752 48.1286149162904 226.759324853414 0.212245361673231 0.832014579903534 PDZRN3 other 1 1 1 1.41018844219793 0.212245361673231 2.46159537207589e-07 61.9915604343725 16.0468619946422 3.86315782207577 0.000128840560124726 -55.6528480372323 31.0694160348545 -1.79124216479639 0.0739447487387195 SEC22A other 0.00155080508440781 1 1 3.86315782207577 -1.79124216479639 0.354111340324425 5.65970254957513 7.27492237421609 0.777974287345574 0.4370042023406 -9.99226021853508 14.0854697909945 -0.709401984229421 0.478452507471473 CSTA other 1 1 1 0.777974287345574 -0.709401984229421 0.259943575380218 2.48012271217478 4.2987049000816 0.576946491983596 0.564272004809616 -9.51321149724245 8.53810190761973 -1.11420683427923 0.265801491069003 POPDC2 other 1 1 1 0.576946491983596 -1.11420683427923 0.819622211796099 -4.20288745190937 50.7071588512368 -0.082885484951734 0.933980460933188 52.4644891448663 100.714726826097 0.520921724143247 0.602684549226296 B4GALT4 other 1 1 1 -0.082885484951734 0.520921724143247 4.69770118728091e-07 254.985835694052 92.4570647131265 2.75788374295913 0.00606109746541991 -519.713071630923 179.012383224377 -2.90322413606161 0.00388002437160802 NAA50 essential 0.0029097561154018 1 1 2.75788374295913 -2.90322413606161 0.24614810383838 20.8773341103144 12.6429326379887 1.65130470185244 0.099398057585838 20.4907579941911 15.8544378887251 1.29243043102544 0.196894226924772 KIF18A essential 1 1 1 1.65130470185244 1.29243043102544 0.000582996597356316 172.73098673562 50.7936304145266 3.40064266574298 0.000734345714981693 -88.2563657178948 106.435235282656 -0.829202523802534 0.407444588472528 DESI2 other 1 1 1 3.40064266574298 -0.829202523802534 0.000115002764686262 551.662110970819 415.126877043034 1.32890000980021 0.1845807977326 -1516.59594101211 557.256826103735 -2.72153856170044 0.00675993750041879 MAPK8IP1 other 0.566158610550466 1 1 1.32890000980021 -2.72153856170044 2.21383169443446e-08 228.42523341191 220.261606606795 1.03706332179665 0.300286477167423 -1287.23187790652 292.294094874835 -4.40389286159795 1.34212559885736e-05 CRY2 other 0.000148481691745719 0.112859341607916 1 1.03706332179665 -4.40389286159795 7.0086809894222e-11 277.286173215481 53.9426578031751 5.1403876729107 4.15868237560324e-07 -90.0252058347951 72.41139020705 -1.24324647790052 0.214449756848812 PEX16 other 5.18081698738089e-07 1 0.00376360754992093 5.1403876729107 -1.24324647790052 4.91072015041657e-07 42.9139351151457 7.88921957216315 5.4395665784948 8.9392748905381e-08 39.7852785976844 9.91352242987499 4.0132333264097 7.05429691856315e-05 DEPDC7 other 0.00303973577310785 0.567800358975148 0.00081865879447548 5.4395665784948 4.0132333264097 2.00654686516198e-07 237.440930991268 95.3485802630321 2.49024086500559 0.0131361718822521 -269.677649198935 119.533981937446 -2.25607517484074 0.0245595086065287 CAT other 0.00127074612970708 1 1 2.49024086500559 -2.25607517484074 1.69551729639024e-18 335.406188104858 138.479536561568 2.42206319022259 0.0158461831323649 -705.298961239741 171.509431055691 -4.11230424413642 4.69615328035017e-05 ZMYM2 other 1.4281342187495e-14 0.38301826154536 1 2.42206319022259 -4.11230424413642 0.522733752964558 -86.8048202324364 86.1889744713013 -1.00714529630864 0.314432673850273 -44.8571945178941 106.746616445197 -0.420221230533556 0.674534240273925 GJB6 other 1 1 1 -1.00714529630864 -0.420221230533556 0.894142752718642 6.64326663725006 14.254473427444 0.466047846036869 0.641417789998882 5.3289495947475 17.6544252547555 0.301847809704939 0.762914354171001 GJA3 other 1 1 1 0.466047846036869 0.301847809704939 8.38315219506107e-06 60.3642588910978 64.4640907069645 0.936401308528443 0.349584976800699 -377.785319827073 108.992872094143 -3.46614702932828 0.000580318235332989 TBC1D15 other 0.0469791849011222 1 1 0.936401308528443 -3.46614702932828 0.239967044427258 78.2044477241465 346.327638191951 0.225810588298477 0.821454311357005 -314.687702502905 444.902977519707 -0.707317591483113 0.479746153992783 ADGRB2 other 1 1 1 0.225810588298477 -0.707317591483113 0.880874471938956 0.70352607771542 2.26785078247194 0.310217093273033 0.756543761992182 1.38241866041749 2.91334982954189 0.474511727496478 0.635372062579216 HCRTR1 other 1 1 1 0.310217093273033 0.474511727496478 2.82069778377942e-44 95.0704296973153 51.7939969842713 1.83554919938282 0.0671037059165931 -461.433097786823 66.5361378498397 -6.93507487357015 1.46802386104187e-11 ZCCHC17 other 2.66161042877426e-40 1.39932034434511e-07 1 1.83554919938282 -6.93507487357015 0.254478992809001 -37.6318859777904 49.317241471246 -0.763057398490776 0.445840879395166 9.06664202496553 63.3544226737538 0.143109851567184 0.886269387423385 FABP3 other 1 1 1 -0.763057398490776 0.143109851567184 1.09787459729863e-31 575.613899148935 142.443955540505 4.04098508051648 6.28897382774096e-05 -584.464730432703 182.987821244953 -3.19400890428834 0.00150463862492941 KHDRBS1 other 9.99505033380677e-28 1 0.527896463100576 4.04098508051648 -3.19400890428834 1.28982195193014e-48 94.4066192409181 16.5587988024338 5.70129635411974 2.19146378902218e-08 -79.2267843549529 21.2719346622558 -3.72447478862984 0.000221355767436201 TMEM39B other 1.22765253384711e-44 1 0.000202798059036113 5.70129635411974 -3.72447478862984 0.706941447028359 -5.89692101740272 8.77025723805164 -0.672377201414077 0.501698939471829 -11.1288791529753 13.9658640993106 -0.796862913303351 0.425963367319579 CCRL2 other 1 1 1 -0.672377201414077 -0.796862913303351 7.70735745609476e-07 325.546373402844 114.460516250598 2.84418054423324 0.00466161464288445 -406.939788836166 185.675639702882 -2.19167032082049 0.0289303412997639 PDS5A other 0.00471073687716512 1 1 2.84418054423324 -2.19167032082049 0.108625401983426 8.25554637340174 15.011119540322 0.549962069866018 0.582626356929062 -33.5589397888372 24.3507483157203 -1.37814819297246 0.168862742503787 TMEM156 other 1 1 1 0.549962069866018 -1.37814819297246 0.000402613861698884 5.35331511029153 13.5129151821693 0.396162858874108 0.692178247409661 -67.1085812032988 21.9203901300503 -3.06146837739447 0.00233841452100435 LIAS other 1 1 1 0.396162858874108 -3.06146837739447 0.348862224193827 -43.1095620482606 136.26695269243 -0.316361092667595 0.751879501787247 72.9403468980584 158.215463348126 0.461019077114894 0.645014275310948 CPXM2 other 1 1 1 -0.316361092667595 0.461019077114894 2.17103775591686e-14 435.256702735807 88.6362212596906 4.91059632901737 1.2860660523234e-06 69.6773562161456 113.912339421104 0.611675228252196 0.541071463380277 TMEM54 other 1.7287973650366e-10 1 0.0114948583756666 4.91059632901737 0.611675228252196 1.23050927285134e-26 5.83294422303046 5.63852832801678 1.03447990037536 0.301483990143048 -38.9232646940416 7.24342433384858 -5.37359995770963 1.25796320713348e-07 ZSCAN20 other 1.09822952601983e-22 0.00113908568405937 1 1.03447990037536 -5.37359995770963 1.92813950826606e-16 155.65910421417 99.8026017254265 1.5596698034227 0.119561804867007 -430.667516380431 128.209446129292 -3.35909349414183 0.00085053265998234 CSMD2 other 1.58396660604057e-12 1 1 1.5596698034227 -3.35909349414183 0.00882872027878381 34.7462720416843 215.829437215637 0.160989494713685 0.872176242034085 496.468732626543 277.376852936244 1.78987081067164 0.0741685144908517 HPCA other 1 1 1 0.160989494713685 1.78987081067164 3.62861991779696e-28 28.8359717585772 27.5556059743788 1.04646480231242 0.295923628947535 -198.866231904847 35.5523995135605 -5.59360928167436 3.92297355156058e-08 LRIF1 other 3.26285503008303e-24 0.00035906976917434 1 1.04646480231242 -5.59360928167436 1.26978289399534e-25 2.60911913505237 68.9232476024756 0.0378554294205755 0.969820196998932 -539.56605480167 88.504165286024 -6.09650464537938 2.38109911063432e-09 TMIGD3 other 1.12756720986786e-21 2.21823193146693e-05 1 0.0378554294205755 -6.09650464537938 6.08391650615332e-33 355.581618845306 73.9684808225499 4.80720456728515 2.10880875970794e-06 -196.662080956814 92.4230053232691 -2.12784771788092 0.0339088425851917 CLCC1 other 5.57043395303398e-29 1 0.0187430922562841 4.80720456728515 -2.12784771788092 1.53750495736477e-08 567.23460910089 170.147660636392 3.33377847793676 0.000929704738162941 58.2821235262847 212.598095430195 0.274142265519125 0.784104831379535 GPSM2 other 0.000104073710564021 1 1 3.33377847793676 0.274142265519125 0.398347399019087 -6.52688997781517 6.09433262734764 -1.07097698417813 0.284776367615366 -10.1148492162169 7.45464337527065 -1.35685219359667 0.175535101361304 FLT3 og 1 1 1 -1.07097698417813 -1.35685219359667 2.93780742452399e-06 73.034325556449 49.7509893939313 1.46799744982273 0.142830933738369 -126.188388307857 60.8558649776295 -2.07356165842427 0.0387107289170038 RPL21 other 0.0171656087814936 1 1 1.46799744982273 -2.07356165842427 4.77482254181358e-16 0.269326409711619 36.8290345121664 0.00731288271004356 0.994168583754176 -256.028742777737 45.0496116525925 -5.68326192803047 2.43085534155526e-08 MTIF3 other 3.90437239244096e-12 0.000223274063121851 1 0.00731288271004356 -5.68326192803047 1.04723200985101e-10 187.006631073403 106.977822995356 1.7480878357519 0.0811575653803852 -399.326165923108 130.856250923128 -3.05163997215306 0.00241597269258044 GTF3A essential 7.70343866446403e-07 1 1 1.7480878357519 -3.05163997215306 0.817701660542127 4.54713669275237 15.5333586508503 0.292733644729401 0.769865977405105 -2.7247860747456 19.0005462850262 -0.143405670230278 0.886036517382119 RASL11A other 1 1 1 0.292733644729401 -0.143405670230278 1.94618587443878e-17 281.243017108582 306.612977466853 0.917257382359121 0.359518391737527 -1996.64043684327 372.895884367877 -5.35441800390992 1.39576244563877e-07 UBL3 other 1.61825355459584e-13 0.00126218797959114 1 0.917257382359121 -5.35441800390992 3.80144879628091e-08 227.097918072787 83.0631642716708 2.73403884939934 0.00651342298986676 -469.000186906184 152.027819011158 -3.08496293610422 0.00216652971064486 FYTTD1 other 0.000251047678506391 1 1 2.73403884939934 -3.08496293610422 2.63766322760624e-21 19.4443483631893 51.2995577936534 0.37903539912375 0.704845251560562 -514.525532034365 75.105466731272 -6.85070680507641 2.50022961461731e-11 MTERF4 other 2.28316128981596e-17 2.37896847830837e-07 1 0.37903539912375 -6.85070680507641 1.27896868332556e-12 306.859468096371 46.6934832119499 6.57178361921474 1.41501651822733e-10 -79.2171747312077 96.342746698449 -0.822243266316208 0.411385841063395 MRPS2 other 9.83015330004023e-09 1 1.34454869561961e-06 6.57178361921474 -0.822243266316208 1.60851716448354e-07 251.034574862736 114.65313704044 2.18951335604706 0.0290864659258648 -832.255972696252 225.524757099876 -3.69030869780597 0.000252202776757506 KIAA1191 other 0.00102462543377602 1 1 2.18951335604706 -3.69030869780597 3.05036328466763e-06 41.5585215605753 26.8654028266955 1.54691600303419 0.122605701511311 -66.2464065708414 35.2897448579438 -1.87721409824614 0.0611531685096615 SERAC1 other 0.017795819402751 1 1 1.54691600303419 -1.87721409824614 0.308369720485943 -347.142397290397 226.806997324093 -1.53056299578955 0.126602631314952 -318.836342622018 274.61270835132 -1.16104001353834 0.246260895058247 ANXA11 other 1 1 1 -1.53056299578955 -1.16104001353834 0.543032760985263 -68.0485011998747 78.5365710229659 -0.866456229416684 0.386715489361928 -104.399578310748 94.5469210103082 -1.10420918201414 0.270110033405842 LDB3 other 1 1 1 -0.866456229416684 -1.10420918201414 1.67234522830878e-25 51.1753423906388 76.0055680614533 0.673310438904445 0.501105736684586 -548.936449008125 91.3813663245932 -6.00709390860127 3.9806325576069e-09 FAM35A other 1.48370468655555e-21 3.69800764601681e-05 1 0.673310438904445 -6.00709390860127 1.53464404898866e-06 574.12391051183 651.314376025483 0.881485088683758 0.378540996740144 -1843.93131603595 788.596502306891 -2.33824435011045 0.0198257885985587 FAM213A other 0.0091633596165113 1 1 0.881485088683758 -2.33824435011045 1.6591148934892e-20 2596.86512044482 725.05008225421 3.58163550905485 0.000379715452541821 -1898.61540595649 935.46373887075 -2.02959807747162 0.0430014631820242 RPL5 other 1.42401831308178e-16 1 1 3.58163550905485 -2.02959807747162 1.64449887742166e-16 96.4649293649229 23.3575894030294 4.1299180193831 4.34711037698995e-05 -22.6729687451438 30.1377574506189 -0.752311076306648 0.45226810883051 ODF2L other 1.35260032667932e-12 1 0.36741776906319 4.1299180193831 -0.752311076306648 2.65482580785671e-13 -1.75921857700073 13.6571734651944 -0.128812787029772 0.897564913873842 72.0437280337741 17.5381675867325 4.10782527179606 4.76730517486724e-05 PTGFR other 2.0712950952898e-09 0.388655486666156 1 -0.128812787029772 4.10782527179606 2.5049090836072e-28 63.1340188198633 21.4190965402453 2.94755750791066 0.00337411093881145 -106.152782247311 27.6350401485043 -3.84123857526065 0.000140493583709915 TRMT13 other 2.2536667025214e-24 1 1 2.94755750791066 -3.84123857526065 2.14518094610428e-20 7.30899235806625 8.37894854684987 0.872304241659788 0.383520347127992 -50.0701551003736 10.8105670591368 -4.63159377546764 4.79094822614541e-06 LRRC39 other 1.83820555271675e-16 0.041182990951946 1 0.872304241659788 -4.63159377546764 6.22224648290966e-43 86.4708584984822 16.4488249374405 5.25696266009 2.29354940557165e-07 -74.0480684561115 21.2235384293543 -3.48895961446727 0.000533982005918382 RWDD3 other 5.85388949112141e-39 1 0.0020855244744863 5.25696266009 -3.48895961446727 1.48046686368734e-50 232.410131497615 62.1453689922947 3.73978198643298 0.00020863750203262 -478.411982409431 80.1847324675582 -5.96637249619796 5.0084499915092e-09 ZNF644 other 1.41488218162599e-46 4.64483652212563e-05 1 3.73978198643298 -5.96637249619796 4.31874766545932e-41 38.2091213954442 16.8803880901789 2.26352150147984 0.0240932350704581 -134.584004407899 21.7883652148705 -6.17687481739316 1.49743161921462e-09 CCDC18 other 4.04277968963647e-37 1.39890061867029e-05 1 2.26352150147984 -6.17687481739316 5.2553239066386e-42 132.339397252628 29.4411447259634 4.49504930886471 8.91519364653917e-06 -157.086577999725 37.9851323323185 -4.13547533875701 4.2471003466398e-05 RPAP2 other 4.93264701877099e-38 0.34737033735167 0.07761567588677 4.49504930886471 -4.13547533875701 5.53782501186814e-10 189.740924193877 93.8068708957213 2.02267618973027 0.0437427543626922 -465.037115334462 141.000619624428 -3.29812107615657 0.00105659549654706 PQLC1 other 3.98446509603912e-06 1 1 2.02267618973027 -3.29812107615657 2.75975146790105e-48 297.032631151987 17.7982805891875 16.6888385461478 9.3926160786516e-49 94.4934501403219 66.2764472481416 1.42574706496464 0.154653641651643 MRM2 other 2.62507559626747e-44 1 9.25266609907969e-45 16.6888385461478 1.42574706496464 2.57880732945878e-29 406.767890850778 58.554323456701 6.94684639557947 1.36945043320941e-11 -264.855650958577 68.1544205727441 -3.88611110963646 0.000117734997948939 SMU1 essential 2.32763149556949e-25 0.930341953792519 1.31029017449477e-07 6.94684639557947 -3.88611110963646 3.21858740136946e-05 399.238656982546 156.294208684158 2.55440467272421 0.0109766158908541 -353.251077338043 183.957268824495 -1.92028876920902 0.0554749617829983 GLIPR2 other 0.169716113674212 1 1 2.55440467272421 -1.92028876920902 1.13037722605384e-07 43.3524486419874 10.4762216598811 4.13817596166434 4.20616612610413e-05 -17.0571941926863 12.3502336288013 -1.38112320020474 0.167951784952295 SLC25A51 other 0.000724910915068328 1 0.355631345962104 4.13817596166434 -1.38112320020474 2.547308711738e-07 774.508614342639 142.088717166077 5.4508804765784 8.41335694449428e-08 290.393650597027 167.237497542013 1.73641470881299 0.0831985117011672 CLTA other 0.00160378556491025 1 0.000771000030393456 5.4508804765784 1.73641470881299 4.61795722028476e-05 43.8948736155988 13.4766971570633 3.2570943090899 0.00121371299294031 -15.2258964150378 15.861985051526 -0.959898547727671 0.337639503769886 RECK other 0.238656029144316 1 1 3.2570943090899 -0.959898547727671 0.0153097937929079 2.1184884414595 10.2718121624086 0.20624291098434 0.836697663061773 28.8287201345954 11.9546413207363 2.41150858157407 0.0163000323865408 TAF1L other 1 1 1 0.20624291098434 2.41150858157407 4.93185489618547e-10 200.933646886037 59.2348197211294 3.39215427398967 0.000757016175929932 -166.596863307341 68.9422441903233 -2.41646997807948 0.0160835047532003 ACO1 other 3.55685375112896e-06 1 1 3.39215427398967 -2.41646997807948 0.550840255588995 121.301786080208 197.498857785653 0.614189810717073 0.539412467460597 -95.7344902899246 230.499064350496 -0.4153357002107 0.678101902374389 PHF24 other 1 1 1 0.614189810717073 -0.4153357002107 0.0288222694283874 18.9162171383256 10.7554151234411 1.75876216038358 0.0793226206363418 -7.83206235918629 12.5349346460813 -0.624818762947024 0.532418362636201 DNAI1 other 1 1 1 1.75876216038358 -0.624818762947024 5.88809094492065e-08 143.652120348517 33.111369893437 4.33845294866494 1.78741079164411e-05 -48.7542488607858 39.0408966908953 -1.24879941274904 0.212413179133147 DCAF10 other 0.000384315695974971 1 0.153681579865561 4.33845294866494 -1.24879941274904 0.0592169727507528 360.919521054185 243.956122016893 1.47944441020911 0.139748720529813 -194.546972448651 284.434630112528 -0.683977799650076 0.494355060991173 CNTFR other 1 1 1 1.47944441020911 -0.683977799650076 3.74260301701704e-05 -34.6154281003416 139.835790597504 -0.247543407538467 0.804603700046113 423.72679896361 169.522381830693 2.49953306688906 0.0128006303588458 PLAU other 0.195700711759821 1 1 -0.247543407538467 2.49953306688906 0.0423142333712227 60.7617705102878 285.547018200758 0.21279077222781 0.831589160546689 577.860035233587 346.708508439338 1.66670278106167 0.0962883915913182 SRGN other 1 1 1 0.21279077222781 1.66670278106167 3.36777239385873e-10 435.553143501558 258.065882650262 1.68775949392672 0.0921692899097017 -796.952090073873 313.341171679992 -2.54340049155041 0.0113207248087763 CHST3 other 2.43894076763249e-06 1 1 1.68775949392672 -2.54340049155041 1.83414564829574e-06 24.5795467679097 17.5689708617964 1.39903167699809 0.162514459550526 96.6058061429295 22.6808536433958 4.25935494588666 2.51321481944546e-05 BICC1 other 0.0108856544226352 0.208446037124806 1 1.39903167699809 4.25935494588666 6.81871867415452e-19 97.1050424710907 51.6415434588779 1.88036677386328 0.0607244919464397 -299.204931244681 66.6672110918461 -4.48803731766239 9.21037619867563e-06 CISD1 other 5.76931787020214e-15 0.078140831669564 1 1.88036677386328 -4.48803731766239 0.123080410917155 228.960940576856 215.782789067141 1.06107137444412 0.289242189319147 -77.3366848140832 277.893058981944 -0.278296568821851 0.780916038890871 EGR2 other 1 1 1 1.06107137444412 -0.278296568821851 3.48617736337809e-22 -32.4936403250498 45.6655428922618 -0.711557079299631 0.477117881002208 -375.856848427748 55.3601589808301 -6.78930218675669 3.6793976150545e-11 ECD essential 3.03820357218401e-18 3.49432391501726e-07 1 -0.711557079299631 -6.78930218675669 0.0128161302918662 30.3902072782959 131.79257278613 0.230591198243109 0.817740070674433 -249.922741726534 159.771620347234 -1.56424990360224 0.118481073487853 P4HA1 other 1 1 1 0.230591198243109 -1.56424990360224 2.12527813086696e-21 76.1838173104041 29.5264084363021 2.58019249021624 0.0101991553768466 -138.476643948309 35.8506878938013 -3.86259377668041 0.000129128614035213 SLC25A16 other 1.84049086133079e-17 1 1 2.58019249021624 -3.86259377668041 4.35405534212778e-07 290.64429667519 62.6144665166832 4.64180744233842 4.57634403910804e-06 449.191023017901 82.1368403248733 5.46881303494546 7.64579005986338e-08 ZWINT essential 0.00270386836746135 0.000695996269149364 0.0402580985120335 4.64180744233842 5.46881303494546 1.06116735152896e-44 112.885537073586 53.2333533911605 2.12057910844164 0.034518652302091 -501.10644661335 64.6354378685801 -7.75281274696744 6.34717618579424e-14 VPS26A other 1.0022725635191e-40 6.13581521880729e-10 1 2.12057910844164 -7.75281274696744 9.5871060787372e-05 156.542648431597 47.7009514166116 3.2817510716795 0.00111457094386358 -82.658762168652 92.666458893454 -0.892003030607778 0.372883324740654 RBM19 essential 0.476287429991664 1 1 3.2817510716795 -0.892003030607778 1.65642966466492e-07 132.531566509116 49.4851208140604 2.67821042626332 0.00768003694511954 -211.266895832052 82.7749097677077 -2.55230596354539 0.011039610787913 IFT81 other 0.00105448312452569 1 1 2.67821042626332 -2.55230596354539 1.31680525693731e-05 160.043271568258 34.5583689648458 4.63110026202511 4.80480635645813e-06 206.580699764108 64.852204745278 3.18540750581266 0.00154902945223878 ACADS other 0.0722926086058584 1 0.0422198334541975 4.63110026202511 3.18540750581266 0.733396361157324 21.9366981769068 87.8677877684286 0.249655746821803 0.802970625512099 -68.4844699527355 146.978487358835 -0.465948937040948 0.641483673358589 HVCN1 other 1 1 1 0.249655746821803 -0.465948937040948 5.87097240428223e-09 368.455555555556 94.7165510635202 3.89008627761855 0.000115811611449766 -345.771111111103 167.799972010362 -2.06061483186511 0.0399311155895102 DDX54 essential 4.05155805619517e-05 1 0.959267577638412 3.89008627761855 -2.06061483186511 0.0207290161967701 329.83252975112 235.985501810726 1.39768132881173 0.162919505736743 -716.651044037553 463.811128318124 -1.54513550943954 0.123038982365624 MED13L other 1 1 1 1.39768132881173 -1.54513550943954 1.80058462975737e-10 823.009068860319 168.351424294573 4.88863739828099 1.43302659194379e-06 347.475678418009 213.259215388249 1.62935832707352 0.103964428701704 CDKN2C other 1.31478689664883e-06 1 0.0127926283862823 4.88863739828099 1.62935832707352 2.64299911623752e-17 100.705823029649 194.36466650102 0.518128242352737 0.604631614341662 -1109.27509041233 249.780239753909 -4.44100418634084 1.13628384418517e-05 RNF11 other 2.19448216621201e-13 0.095947807802996 1 0.518128242352737 -4.44100418634084 2.9686794263424e-17 48.0576096615229 30.5372516765066 1.57373722333026 0.116275210492771 -154.46354309718 35.9699303730003 -4.29424081435319 2.16349240884369e-05 SPRYD7 other 2.46370705592156e-13 0.179916028719442 1 1.57373722333026 -4.29424081435319 1.75653363846432e-06 5.37342407841223 34.3631095694915 0.156371880942431 0.875812444693627 -125.304515712092 40.4764211170097 -3.09574098337056 0.00209007672324831 EBPL other 0.0104461055479473 1 1 0.156371880942431 -3.09574098337056 1.11791621471925e-09 19.2686130252663 23.1938340902874 0.830764458789292 0.406561395964834 -90.589444838761 26.9137868868718 -3.36591224488551 0.000830464670261858 ATP7B other 7.94838428665385e-06 1 1 0.830764458789292 -3.36591224488551 1.1088659945707e-16 346.441595281565 180.877658362416 1.91533657842593 0.0561019733712597 -865.987105998902 216.53364290082 -3.99931897139677 7.45826138069811e-05 ZC3H13 other 9.14592672321917e-13 0.599047554097673 1 1.91533657842593 -3.99931897139677 2.44412534729198e-06 416.242899648359 105.052982891319 3.96221876040376 8.67045694331231e-05 -103.53735390928 212.859975619685 -0.486410625613663 0.626919896238306 OPTN other 0.0143787894181187 1 0.723202813641679 3.96221876040376 -0.486410625613663 5.58862690792476e-08 -41.9813751976775 45.58602126076 -0.920926504147767 0.357598068358948 405.199804618709 94.1202735406033 4.30512778358965 2.06295148222047e-05 ITIH5 other 0.000365216768432883 0.171699451865209 1 -0.920926504147767 4.30512778358965 1.26395751380368e-05 11.8342944740497 15.8124672880878 0.74841542805688 0.454612218522674 -79.6982383142317 23.9289399390299 -3.33062135294334 0.000940045494016566 ATF1 other 0.0695555819846164 1 1 0.74841542805688 -3.33062135294334 1.45907757814676e-10 78.853533007223 32.9628148134132 2.39219658435044 0.0171898065206193 -226.972080270363 55.3485063244551 -4.10078058728168 4.9517815828401e-05 TSFM essential 1.06833660271906e-06 0.403223574290669 1 2.39219658435044 -4.10078058728168 0.294207343022111 -9.27703554475203 18.8228944222208 -0.492859139336206 0.622360806990671 -43.8287542749604 29.3537827475593 -1.49312116437888 0.136130403497525 NEUROD4 other 1 1 1 -0.492859139336206 -1.49312116437888 2.0259022820372e-06 83.2541568769202 31.0846054790407 2.6783083006492 0.00768573523464764 277.770513283933 53.4456776265715 5.19724934960566 3.14421392599515e-07 ARHGAP9 other 0.0119953674119423 0.00281878778465465 1 2.6783083006492 5.19724934960566 6.94276957867144e-06 -10.4506345642952 175.968492650531 -0.0593892372826644 0.952669421369023 1052.4263491013 268.935741736369 3.91330041260552 0.000105666956846057 NCKAP1L other 0.0391711059628643 0.838678636487155 1 -0.0593892372826644 3.91330041260552 0.000168787901611953 293.31763835351 70.8744929249996 4.13855007984189 4.1944154792904e-05 339.107623554472 111.552995662012 3.03987913136744 0.0025089184976598 MMP19 other 0.812674660597874 1 0.354679772928796 4.13855007984189 3.03987913136744 0.00358835989920924 1196.72066435356 377.734264261153 3.16815491095134 0.00164148755623001 537.084843386558 588.955201041165 0.911928177961737 0.362308159861414 PFDN5 other 1 1 1 3.16815491095134 0.911928177961737 1.92057422819359e-07 70.7796732027934 64.1966949748727 1.10254388065456 0.270830726992988 -367.337700584299 98.0203052676639 -3.74756740025661 0.000202464682440166 SPATS2 other 0.00121764406067474 1 1 1.10254388065456 -3.74756740025661 0.000494626714403065 123.830147346995 31.7587409980761 3.899088674658 0.000111729525128301 91.7913978368868 49.9867096127004 1.83631606377157 0.0669900419013845 ORMDL2 other 1 1 0.926014304263359 3.899088674658 1.83631606377157 0.0771865561353787 468.967908653842 406.809293842349 1.15279546399838 0.249624530657166 -563.067868589736 628.27382203525 -0.896214116904818 0.370631832438434 NR4A1 other 1 1 1 1.15279546399838 -0.896214116904818 0.632649017041834 -112.616819755121 119.974245699038 -0.938674955603607 0.348419751035858 -75.8234608424525 183.358749457554 -0.413525185281682 0.679426129336141 PDE1B other 1 1 1 -0.938674955603607 -0.413525185281682 0.0445100094647219 159.077968454892 71.7198454865651 2.21804672577956 0.0270662526395846 44.660514828204 115.289330551278 0.387377692407885 0.698665642565542 CDK2 essential 1 1 1 2.21804672577956 0.387377692407885 7.78756879800685e-05 3792.56648456494 2153.2344206131 1.76133469178198 0.0788875064522364 -9057.1671589514 3744.07528859918 -2.41906651464268 0.0159716601814737 LRP1 other 0.391169580723884 1 1 1.76133469178198 -2.41906651464268 0.000683466786352041 181.301377588759 59.0806977763151 3.06870745290082 0.00228367058873174 -5.64881040433454 91.2438736338695 -0.0619089280119922 0.950663662151566 ATG101 other 1 1 1 3.06870745290082 -0.0619089280119922 8.50413145931467e-06 -15.1895723641973 26.10036315806 -0.581967855091192 0.560889120472791 -176.28289456787 41.5650248126707 -4.24113531418203 2.71735185392931e-05 IKZF4 other 0.0476316403036215 0.225078254060965 1 -0.581967855091192 -4.24113531418203 9.04222878521083e-08 105.118304068065 34.5699614556945 3.04074114177959 0.00250222823560716 -112.148079587291 52.8269344395856 -2.12293370374437 0.034322245102417 SMUG1 other 0.000585122624690992 1 1 3.04074114177959 -2.12293370374437 0.0544639287212256 5014.84449342008 2369.52338000369 2.11639375907414 0.0348747890947476 1261.89566713033 3617.96514817061 0.348786020718966 0.727417557412565 TUBA1B essential 1 1 1 2.11639375907414 0.348786020718966 0.0696685543484673 41.3700480055371 18.4576035452594 2.24135532568433 0.0255284727191735 23.1954289982588 30.992522706021 0.748420166318135 0.454628664537728 EEF1AKMT3 other 1 1 1 2.24135532568433 0.748420166318135 1.44489501389058e-22 132.429593109954 37.2165573843523 3.55835150850448 0.000414155670146707 -313.345861610723 48.5331699866616 -6.45632382341479 2.86467703104453e-10 KBTBD4 other 1.26197130513203e-18 2.69938516635326e-06 1 3.55835150850448 -6.45632382341479 0.223432130124557 1.80161900453351 15.2314843701605 0.118282562667562 0.905897998072845 51.034180054095 31.4271487062719 1.6238883307893 0.105119049576814 SARDH other 1 1 1 0.118282562667562 1.6238883307893 1.54384530126296e-21 -40.6889864300479 125.00396141686 -0.325501575860939 0.744956926644954 -933.119009843429 160.517265907942 -5.81320024712219 1.18206259854962e-08 ATPAF1 other 1.33758756901423e-17 0.000109057095342188 1 -0.325501575860939 -5.81320024712219 4.88813399338642e-21 96.1889155069424 18.6575966721924 5.15548262710085 3.83730328557347e-07 -8.72375713827892 23.9581719834161 -0.364124489310683 0.715940761170635 STIL essential 4.22188133008785e-17 1 0.00347544558574389 5.15548262710085 -0.364124489310683 3.39786193884026e-07 207.237927687455 39.2262030016853 5.28315033903616 2.00763276527382e-07 144.088617919061 60.0847564669899 2.39808940555867 0.0168993605638597 HJURP essential 0.00212264435319351 1 0.00182794963278181 5.28315033903616 2.39808940555867 0.0232146172117314 -226.756855655516 201.817066842644 -1.12357621286963 0.261808293725209 -699.474374332956 276.776167392517 -2.52722039228536 0.0118478318282126 AMD1 other 1 1 1 -1.12357621286963 -2.52722039228536 0.0009863699682153 9.72435657043433 40.7266128545069 0.238771552281402 0.811395434949733 -128.749706135389 55.1278459371415 -2.33547500263648 0.0199733976304451 NDUFAF4 other 1 1 1 0.238771552281402 -2.33547500263648 6.69757022360304e-13 30.6754180602023 15.0698530103282 2.03554859089726 0.0423984719304798 -69.9131346913945 20.2768696393939 -3.44792544089583 0.000619657493432359 USP45 other 5.17923105391223e-09 1 1 2.03554859089726 -3.44792544089583 0.1019766902778 4.39243367475372 40.1529904707614 0.109392441839474 0.91294132807004 -144.889017099496 78.1999947984893 -1.85280085341253 0.064583347557397 SLC36A1 other 1 1 1 0.109392441839474 -1.85280085341253 6.69442330802125e-09 141.806101656542 32.355105111097 4.38280454257917 1.46975200133737e-05 -28.6484585487339 45.4909026245095 -0.629762367768423 0.529179943160747 EXOSC9 essential 4.61178821689584e-05 1 0.126810202675388 4.38280454257917 -0.629762367768423 2.20540416802431e-14 55.2174770039422 46.8460977908411 1.1786996058984 0.239157737980202 -361.468481321572 65.8529043124211 -5.48902869350581 6.8549434247575e-08 PLA2G12A other 1.75594279858096e-10 0.000624279697692665 1 1.1786996058984 -5.48902869350581 1.05520613776707e-29 57.6498388680655 9.47078983599613 6.08712049009394 2.53056100962743e-09 -13.0555248198502 12.7239510982205 -1.02605902200269 0.305435298394906 B9D2 other 9.53906348541432e-26 1 2.37644984414112e-05 6.08712049009394 -1.02605902200269 3.94156093529199e-80 444.677587681281 44.6405165554869 9.96130022663514 3.42527679326878e-21 -253.187726268801 60.9344936671186 -4.1550804976234 3.91635474827342e-05 COQ8B other 3.86982452626968e-76 0.320945271621007 3.35231839757215e-17 9.96130022663514 -4.1550804976234 8.91178716036945e-08 218.466396098472 38.3596801617199 5.69520901054032 2.26249540626101e-08 262.621031944861 81.7444519586731 3.2127077208571 0.00141193708966768 CKS2 other 0.000576949100762318 1 0.000209280825079143 5.69520901054032 3.2127077208571 0.391432779310809 -4.45791261903624 8.71845557898059 -0.511319072357708 0.609385307533791 13.5826824802351 17.0970612367822 0.794445448379964 0.427366387585907 DAW1 other 1 1 1 -0.511319072357708 0.794445448379964 0.420897328043698 6.62628769432485 7.65531199075781 0.865580358099671 0.387194184758045 -10.0960854092526 19.0451595052691 -0.530112935334536 0.596302257940162 FAM124B other 1 1 1 0.865580358099671 -0.530112935334536 0.103266243191666 -61.5949737121045 235.259606611331 -0.26181703947956 0.793585580049658 -1127.29625187833 542.97228275818 -2.07615800598865 0.0384620581947574 SLC12A4 other 1 1 1 -0.26181703947956 -2.07615800598865 0.0129038521939474 132.503292679009 46.0229775530914 2.87906823338746 0.0041839123910092 37.8706914090517 106.219684463788 0.356531763394216 0.721614054025495 ENKD1 other 1 1 1 2.87906823338746 0.356531763394216 7.70446350273074e-10 29.8028935720419 11.7089559375877 2.54530751767284 0.0112615734510765 -62.885340556253 19.1960860502546 -3.27594596063081 0.00113716626558165 FASTKD3 other 5.50954716820825e-06 1 1 2.54530751767284 -3.27594596063081 2.17066694363001e-63 659.424037003829 106.394151265933 6.1979350289246 1.32201147231861e-09 -664.857452186861 138.80009008845 -4.79003617190149 2.2860523861183e-06 PEPD other 2.10836880234783e-59 0.0198977999687737 1.2448060023352e-05 6.1979350289246 -4.79003617190149 0.000150512772075107 233.713058787694 70.971418831554 3.29305884869508 0.00107174882293076 125.464597192238 94.1117620927947 1.33314470372501 0.183180471549133 CHST8 other 0.730137457336346 1 1 3.29305884869508 1.33314470372501 0.126938701694687 -546.13295254017 317.141683847324 -1.72204721219518 0.085768559944648 -960.078619856963 516.287523484738 -1.8595812917903 0.0636165843020473 ATP8A1 other 1 1 1 -1.72204721219518 -1.8595812917903 0.00394123897219821 960.071904355246 346.924791727492 2.76737761972739 0.00589034260308952 -533.610555545877 271.003273725891 -1.9690188543095 0.0495808970662968 USP22 other 1 1 1 2.76737761972739 -1.9690188543095 0.516158657004329 96.7515704256917 273.011870478384 0.354385947600589 0.723220605248001 -63.7222147942661 333.17139908691 -0.191259558800375 0.848411072311815 HIF3A other 1 1 1 0.354385947600589 -0.191259558800375 2.0979657866565e-71 116.369817122993 17.5933700349717 6.6144130937777 1.09722185959077e-10 -86.567579813706 21.6787439930606 -3.99320089030141 7.65190174417284e-05 ZNF576 other 2.04992237014207e-67 0.614079009156972 1.04345798847082e-06 6.6144130937777 -3.99320089030141 4.09269205260137e-57 170.689722181908 23.3990091682195 7.29474145485352 1.42822630182483e-12 -49.018898509717 28.8325163650163 -1.70012557659357 0.0898221036097449 ZNF45 other 3.94781075393928e-53 1 1.37423934761585e-08 7.29474145485352 -1.70012557659357 0.460363204246664 334.690680689995 283.674789326728 1.17983935577902 0.238707452610676 138.626807549762 499.870040275521 0.277325697441985 0.781661470100362 F13A1 other 1 1 1 1.17983935577902 0.277325697441985 0.0424259535528119 -22.2971248038675 10.7285001316977 -2.07830773455368 0.0382627318885461 -53.2878659372663 25.1880953977339 -2.11559727306974 0.0349429185018806 GRM4 other 1 1 1 -2.07830773455368 -2.11559727306974 0.000139839962756186 21.8686743419841 25.1706912081858 0.868815010327258 0.385424134466723 -223.970267402114 62.6611615302572 -3.57430762425247 0.000390195992032923 TRERF1 other 0.680321418808845 1 1 0.868815010327258 -3.57430762425247 0.237842209438448 -820.848776557404 514.126563694005 -1.59658892289011 0.111078564480295 -1379.14301768375 1207.05306183228 -1.14257033206994 0.253841201161551 PACSIN1 other 1 1 1 -1.59658892289011 -1.14257033206994 0.00617608937130745 134.662114787306 43.0767300596228 3.1260988148571 0.00189016135885945 176.383856853477 89.5461317185915 1.96975406383586 0.0495005805144097 BTN2A2 other 1 1 1 3.1260988148571 1.96975406383586 8.72285946248325e-06 15.2294960307037 20.8327743261391 0.731035424868742 0.465150189804233 -139.242786605959 36.8896662956194 -3.77457430734455 0.000182465720521855 SIRT5 other 0.0487956758331313 1 1 0.731035424868742 -3.77457430734455 2.66100335981609e-05 58.6440729109625 30.7707840333173 1.90583616093322 0.0573258337494955 -175.256898266632 60.6894530524753 -2.88776532744654 0.00407208926161141 MRS2 other 0.141698428910207 1 1 1.90583616093322 -2.88776532744654 1.16230796271689e-16 238.874706820318 43.6261862850471 5.4754890849167 7.4067005076361e-08 -243.862838288494 75.289160562697 -3.23901656580987 0.00129179842204869 WRNIP1 other 9.58090453667536e-13 1 0.000679416637565459 5.4754890849167 -3.23901656580987 5.06883552855368e-21 287.72893809141 29.0673670453648 9.89869284143821 5.60333992748982e-21 89.489102603749 72.3632940964222 1.23666430227053 0.216875936896386 RRP36 other 4.37592571180039e-17 1 5.48286811904879e-17 9.89869284143821 1.23666430227053 0.000618370578778905 20.0647022282242 5.48412311460604 3.65868923963162 0.000284607978625753 30.8035948683322 11.4001691888353 2.70202962413046 0.00716127421246297 BTN2A3P other 1 1 1 3.65868923963162 2.70202962413046 1.29256805756672e-13 461.46338153598 61.2019059412377 7.54001651482959 2.73076197150552e-13 69.5376927752575 143.68825338562 0.483948347459116 0.628664398227903 SNRPC essential 1.01569997963593e-09 1 2.63463915010853e-09 7.54001651482959 0.483948347459116 0.0670712198431162 464.074989866234 202.585161996843 2.29076495678132 0.0224556222763621 543.187430605732 349.595656610077 1.55375909378525 0.120970780804207 SERPINB6 other 1 1 1 2.29076495678132 1.55375909378525 3.44694970739129e-06 222.060322807541 82.2843207452308 2.69869545979586 0.00723032174513415 -625.382414639862 204.842650961751 -3.05298926616917 0.00240374719830719 XPO5 essential 0.0200267777999434 1 1 2.69869545979586 -3.05298926616917 4.13228524913149e-05 96.7342760892919 26.9896145416772 3.58412958954696 0.000376208986302701 -88.5307012672904 67.1892790884271 -1.31763136125893 0.188315863249671 ABCC10 other 0.215126770069785 1 1 3.58412958954696 -1.31763136125893 0.000310655583596469 130.265649872285 71.652891560971 1.81800967182795 0.0697456241455796 -486.716451338244 178.376246209395 -2.7285945392465 0.00661644785401563 PEX6 other 1 1 1 1.81800967182795 -2.7285945392465 0.0199053610050796 89.0789420348606 41.5301007672676 2.14492477478093 0.0325133427781778 -32.475723022153 71.6673556133488 -0.453145267384529 0.650670605297564 NQO2 other 1 1 1 2.14492477478093 -0.453145267384529 3.67029324529907e-10 269.702380952382 45.8315636494049 5.88464279804 7.93714084760395e-09 -86.8595848595841 106.825789412629 -0.813095651688348 0.41660496961106 PRICKLE4 other 2.65472310432482e-06 1 7.3990026981364e-05 5.88464279804 -0.813095651688348 5.28176615085516e-11 136.659515032832 28.4571091749375 4.80229787898447 2.15849705652137e-06 -195.666570671581 66.3302301399512 -2.94988529752937 0.00334968742490407 OARD1 other 3.91695777747419e-07 1 0.0191739293530793 4.80229787898447 -2.94988529752937 0.0261736840173893 103.083342932842 38.7723835268109 2.65867954343225 0.00813273141035132 48.1196866720412 90.3739415904136 0.532450901501296 0.594684355473659 UNC5CL other 1 1 1 2.65867954343225 0.532450901501296 9.31941105371252e-08 69.9249407426918 30.5700869679312 2.28736479605193 0.0226527476833708 -234.016065314723 61.7811484333336 -3.7878231669203 0.00017330211555148 AARS2 essential 0.000602779506954126 1 1 2.28736479605193 -3.7878231669203 0.00905533842531241 5.84861008058249 16.6295485913312 0.351699870171539 0.72523365729817 -94.0623321197066 35.3749935962431 -2.65900633632047 0.0081263088602163 ZNF391 other 1 1 1 0.351699870171539 -2.65900633632047 1.07068104650542e-10 704.379394427713 133.296018090229 5.28432435206666 1.99356639857331e-07 -677.798071894041 312.94894706437 -2.16584231470389 0.0308621683013109 RPS10 other 7.87271773495437e-07 1 0.00181534156254086 5.28432435206666 -2.16584231470389 0.0287569351662134 -674.271742886778 313.952973738472 -2.14768388672265 0.0322881659341827 -1680.59031217603 731.788070010126 -2.29655330696054 0.0221165203789559 MOCS1 other 1 1 1 -2.14768388672265 -2.29655330696054 3.94935789119371e-07 94.1224089635863 27.144823570973 3.46741649351646 0.000577412644647212 -167.058988723694 63.2700910799798 -2.64041011909584 0.00857638717689409 MED20 essential 0.00245808035147897 1 1 3.46741649351646 -2.64041011909584 1.49845499980448e-09 52.9386406545005 19.1973120613908 2.75760692357393 0.00606614273902615 -216.2443885043 47.7907365386278 -4.52481807493207 7.79654004397813e-06 TBCC essential 1.0591079938618e-05 0.0663719453943858 1 2.75760692357393 -4.52481807493207 8.59566054916831e-06 54.39393694422 23.342837634691 2.33021956436789 0.020248978796783 -134.461438965238 47.1739756866327 -2.85033086586635 0.00457404596872794 MAD2L1BP other 0.048109912093695 1 1 2.33021956436789 -2.85033086586635 2.99819893166384e-08 1031.70277691878 227.614690683678 4.53267218306471 7.52892166531851e-06 -1157.12313377453 566.647428950248 -2.04205132619798 0.0417462685458302 KLHDC3 other 0.000199560120891545 1 0.065689841529904 4.53267218306471 -2.04205132619798 0.14337336986015 0.0346870025543403 3.17667935166709 0.0109192646516674 0.991292832098905 -14.5423376399017 7.90818243083884 -1.83889759335751 0.0666070287497816 GNMT other 1 1 1 0.0109192646516674 -1.83889759335751 0.284178578307414 28.3159663865548 18.0711487184874 1.56691568575198 0.117856547826584 15.1449256625728 42.1208567574262 0.359558822599272 0.719350369134419 TREM1 other 1 1 1 1.56691568575198 0.359558822599272 1.68112222933407e-18 602.307811243736 69.165906428621 8.70816045569093 6.40628658825812e-17 -65.2007081452169 172.188723544469 -0.378658409233044 0.705125433955188 MEA1 other 1.41617736599102e-14 1 6.23587936501045e-13 8.70816045569093 -0.378658409233044 4.46483148756346e-06 -2.50414353011955 23.5257309414785 -0.10644275140053 0.915280032196664 239.400252580936 53.193192492255 4.50058064508523 8.70598214235786e-06 COL21A1 other 0.0257174652674669 0.0739312003529029 1 -0.10644275140053 4.50058064508523 0.24321539619628 -704.819070438056 534.836534608461 -1.31782147409588 0.188252251873509 -1848.9911015931 1255.67539642464 -1.47250723145316 0.141602146558079 CDKN1A other 1 1 1 -1.31782147409588 -1.47250723145316 0.000551464164250592 1353.76695221785 864.8180038739 1.56537785540279 0.118218157647355 -3812.5168780544 1607.56312937404 -2.37161254098863 0.0181431545740462 SOX4 other 1 1 1 1.56537785540279 -2.37161254098863 6.35749098554933e-12 575.383253466769 115.248476489415 4.99254542006563 8.61781792324064e-07 -849.385522242485 270.577395220623 -3.139159210066 0.00180889943551754 GLO1 other 4.81134917786373e-08 1 0.00774397118582404 4.99254542006563 -3.139159210066 0.00331567225342272 -445.50311691616 239.898972400553 -1.85704470702074 0.0639758749663563 -1882.66654651345 563.228608702759 -3.34263302222813 0.000901097255879322 CPNE5 other 1 1 1 -1.85704470702074 -3.34263302222813 0.595655521809346 -3.81114798963496 35.0420325830645 -0.108759330115938 0.913443417120268 50.8773109733024 62.6207901278061 0.812466768136656 0.416967233988135 RREB1 other 1 1 1 -0.108759330115938 0.812466768136656 1.88826257556273e-12 705.487116778753 159.350396921613 4.42726927831748 1.20773493419606e-05 -854.220092002215 284.762241994876 -2.99976600134223 0.00285670510425615 SSR1 other 1.44584265410839e-08 1 0.104614000000063 4.42726927831748 -2.99976600134223 2.98207592174762e-11 123.982050834133 30.3125955265389 4.09011662249728 5.13573428958548e-05 -159.012286371445 54.1691946149793 -2.93547444265442 0.00350647485244652 RIOK1 essential 2.22343580725502e-07 1 0.432685613897577 4.09011662249728 -2.93547444265442 0.380554346120611 -146.068757789782 184.678953220186 -0.79093342929895 0.429411878137448 -442.516618196925 318.636938579605 -1.38878003338075 0.165607026554473 NRN1 other 1 1 1 -0.79093342929895 -1.38878003338075 2.74921543476625e-06 50.873453285585 15.4146013109219 3.3003418161415 0.00104498245578864 -46.1763763938628 27.5461907441281 -1.67632529748986 0.0943913327235668 SLC35B3 other 0.0160994055859912 1 1 3.3003418161415 -1.67632529748986 3.67608583691783e-05 34.101732588624 8.84756942267727 3.85436168505416 0.000133486165498849 -1.89026646441436 15.2661361285876 -0.123820883587866 0.901514157423169 RPP40 essential 0.192350797979299 1 1 3.85436168505416 -0.123820883587866 0.019108108799653 31.7991170504703 104.078777966864 0.305529308391709 0.760108865953297 -467.995012528341 199.890119534967 -2.3412613570751 0.0196683180139424 ATXN1 other 1 1 1 0.305529308391709 -2.3412613570751 5.34487986911887e-05 132.395861105822 77.209426391376 1.71476291553708 0.0870976606447712 -424.631096722315 148.279431511307 -2.86372217909356 0.00438852921611467 NUP153 essential 0.273978542091033 1 1 1.71476291553708 -2.86372217909356 4.49066016440869e-05 644.159760923996 151.216075192131 4.25986298153517 2.50659970922988e-05 187.088738120241 288.238611458706 0.649075906844784 0.516630284570874 DEK other 0.232436570109794 1 0.214163879156601 4.25986298153517 0.649075906844784 3.28136491123971e-12 60.2901664187362 16.1876386746953 3.72445713858083 0.000221432015877035 -102.114457845306 28.5246200957454 -3.57987091510946 0.000382397303948483 EEF1E1 other 2.50171260832916e-08 1 1 3.72445713858083 -3.57987091510946 0.00938877779766447 50.8935989577998 18.9203411205171 2.68988802229423 0.00742131547292013 105.318668852555 43.7767298777648 2.40581398260287 0.0165509286484924 RUNX2 other 1 1 1 2.68988802229423 2.40581398260287 0.000217465432223186 -57.0463479737943 75.971374724912 -0.75089266424829 0.453120474769662 -400.08446191885 115.607054263821 -3.46072706779499 0.000591556043241913 LRRFIP1 other 1 1 1 -0.75089266424829 -3.46072706779499 0.0649612117034627 -0.398204319339881 10.4543612801332 -0.0380897798219966 0.969633454118008 26.4816365746967 15.9085960492648 1.66461179180677 0.0967053729505641 RAB17 other 1 1 1 -0.0380897798219966 1.66461179180677 0.526207065950853 -280.306797277408 511.908444432325 -0.547572129989478 0.584265279996574 938.643092347316 1230.46375707784 0.762836846634512 0.445972280347666 MYRF other 1 1 1 -0.547572129989478 0.762836846634512 1.2877864674995e-06 166.395684113481 54.2505535938775 3.06717025155407 0.00229488433951953 -360.889107663558 127.338816618515 -2.83408560914084 0.0048081620854052 EMC3 essential 0.007731869950867 1 1 3.06717025155407 -2.83408560914084 0.0211085266955297 112.841740398751 88.7270388293924 1.27178526284109 0.204125824318401 -182.812432960084 140.936263052604 -1.29712842529285 0.1952713980062 SH3TC1 other 1 1 1 1.27178526284109 -1.29712842529285 6.93914591809503e-05 601.770347685488 173.881207055498 3.4608130336559 0.000591372251467167 -544.35680861771 401.312733977531 -1.35644040801404 0.175657843731158 CNOT1 essential 0.350773826159704 1 1 3.4608130336559 -1.35644040801404 0.295991282900552 5.39401485552404 6.343864661649 0.850272687583146 0.395639109089533 -13.5587744908616 14.6417002460782 -0.926038251226549 0.354937216421395 LRRC29 other 1 1 1 0.850272687583146 -0.926038251226549 0.000102370492430026 518.024230645554 175.746039623393 2.94757271205445 0.0033743452265831 -838.280491044576 405.03006576196 -2.06967472764662 0.0390699117235923 BBS2 other 0.506836308021061 1 1 2.94757271205445 -2.06967472764662 0.811511055573287 36.5838425077953 56.7736597746568 0.644380556987203 0.519666772757679 20.4381335551795 130.842431507149 0.156204171076283 0.875944222327286 MT1G other 1 1 1 0.644380556987203 0.156204171076283 0.0120118747605027 3266.36958375855 1246.30304901123 2.62084698127793 0.00907690653803347 6311.17096377274 2872.27073214319 2.19727579755811 0.0285249002097807 MT2A other 1 1 1 2.62084698127793 2.19727579755811 0.0634522443995613 24.8725010440197 26.4727638112225 0.939550597035719 0.347965966403198 -103.205927179146 61.0983636525615 -1.68917661634985 0.0918972538466113 C16orf70 other 1 1 1 0.939550597035719 -1.68917661634985 0.0709896005201385 234.763299128416 155.30925905379 1.51158598372495 0.131361993870232 -393.031016987968 358.455253664729 -1.09645768326659 0.273482384576696 GOT2 other 1 1 1 1.51158598372495 -1.09645768326659 0.666519679221203 -14.1885176998034 50.8580290945593 -0.278982846020694 0.780389663697374 -107.215760141972 119.082937330093 -0.900345276542631 0.368431286757342 DOK4 other 1 1 1 -0.278982846020694 -0.900345276542631 0.0847180772512005 1.06945779426096 17.7035094244902 0.0604093667881194 0.951857215097244 -37.3687271221953 23.4350427123864 -1.59456620501248 0.111532217584051 CLYBL other 1 1 1 0.0604093667881194 -1.59456620501248 0.0134879669726168 76.1206913861935 106.251927093936 0.716417042665926 0.474117429243093 -223.840285366318 139.602949231996 -1.60340656553275 0.109569057538307 TMTC4 other 1 1 1 0.716417042665926 -1.60340656553275 5.38641918789571e-08 1732.42977240573 705.733046379337 2.45479474327257 0.014485325580014 -2122.35139740677 934.215001606587 -2.27180188046319 0.0235837970470052 RAP2A other 0.000352379543272138 1 1 2.45479474327257 -2.27180188046319 2.89852733535376e-05 96.7113842690058 56.4531272981959 1.71312713568831 0.0874000353369977 -148.950334095667 74.7388692841905 -1.99294337099604 0.0468905022900668 ABCC4 other 0.153824845687224 1 1 1.71312713568831 -1.99294337099604 0.473326404526584 -89.2416696131307 93.3411475963315 -0.956080698718965 0.339558853537027 -155.038496370264 128.915174502976 -1.20263961917598 0.229765523496056 EFNB2 other 1 1 1 -0.956080698718965 -1.20263961917598 0.573323377645919 121.509826719408 119.239380374075 1.01904107802481 0.308748579873044 141.071974483362 157.862228185021 0.893639828255938 0.372007629849521 SOX21 other 1 1 1 1.01904107802481 0.893639828255938 2.6555118334211e-15 631.29641695659 170.933592699743 3.6932261645346 0.00024947923176914 -708.047040026758 226.273556832672 -3.12916387552238 0.00187043911001986 TM9SF2 other 2.14538801022091e-11 1 1 3.6932261645346 -3.12916387552238 1.72977153609249e-06 39.9523101364835 7.6433007856813 5.22710164845649 2.67085629954932e-07 17.6241655188105 17.292815697474 1.01916112604987 0.308689079229244 C17orf53 other 0.0102938704112864 1 0.0024262058625106 5.22710164845649 1.01916112604987 7.25886847356651e-13 21.6456173509292 95.4676887944183 0.226732391076747 0.820738102377374 -642.588477827165 125.702059157052 -5.1119964313736 4.78063150705914e-07 ATP5S other 5.60820178267748e-09 0.00426288911484463 1 0.226732391076747 -5.1119964313736 2.93555392677564e-05 -10.6489518790208 33.0404124781605 -0.322300815283697 0.747379654694443 -129.713481945731 41.1305421180193 -3.15370221898688 0.00172383735636619 BMP4 other 0.155672424736912 1 1 -0.322300815283697 -3.15370221898688 6.37176410230799e-10 43.2781274152609 64.346593103843 0.672578381040599 0.501570218950654 -548.711579190379 106.742062409583 -5.14053754259407 4.13657995475525e-07 FAM193A other 4.57301509622644e-06 0.00369686150556477 1 0.672578381040599 -5.14053754259407 4.25291148444953e-05 15.8766275583112 11.8379887313364 1.34115920521905 0.180565390956256 -56.1406894608678 19.6388040355069 -2.85866131966924 0.00445782013418233 GRK4 other 0.220938751617153 1 1 1.34115920521905 -2.85866131966924 0.0472436741485596 0.245523895657498 2.73785924191838 0.0896773259553923 0.928584626298393 -5.0368665710286 2.03205727034445 -2.47870305848949 0.0135616872636989 TEKT3 other 1 1 1 0.0896773259553923 -2.47870305848949 0.000921351741592827 -12.8690764548784 35.4081046129934 -0.363450023533763 0.71644409174019 -98.8144223095115 26.5024290022275 -3.72850436845642 0.000217894424853396 HS3ST3B1 other 1 1 1 -0.363450023533763 -3.72850436845642 0.00306206512620387 95.6333572145013 28.1539940563289 3.39679538978248 0.000744033485453079 6.47935197056849 21.9470190468465 0.295226971678393 0.767960392285233 SLC25A35 other 1 1 1 3.39679538978248 0.295226971678393 1.88763553903421e-11 120.531207875496 21.1217286401599 5.70650300119485 2.12716954516836e-08 -80.0843919774522 44.5077180056541 -1.79933718388524 0.0726535191967736 TTF1 other 1.41421654584443e-07 1 0.000196912084796235 5.70650300119485 -1.79933718388524 5.19142655453982e-06 281.634471631062 82.5902336468476 3.41002149037766 0.0007097634675621 -347.880652342634 174.034184976024 -1.99892137507674 0.0462343216163066 GTF3C4 essential 0.0297053427450768 1 1 3.41002149037766 -1.99892137507674 4.98480575933822e-08 81.4750929292109 18.1380193013584 4.49195094434092 9.04009388998053e-06 -66.3645837588335 38.2204440744041 -1.73636349252355 0.0832027228487858 DDX31 other 0.0003269035616974 1 0.0786759371245006 4.49195094434092 -1.73636349252355 0.818159365039637 -3.77703116702749 6.99245877939292 -0.54015780231105 0.589362744336335 1.30804501450104 14.7345129189683 0.0887742283504422 0.929301915280986 BARHL1 other 1 1 1 -0.54015780231105 0.0887742283504422 4.72261088856367e-22 453.553185648615 132.108747813967 3.43318056641714 0.000653679046124304 -238.175323085574 163.365384903092 -1.45793016817399 0.145581359123779 PPP1R12C other 4.11244956176124e-18 1 1 3.43318056641714 -1.45793016817399 7.31051202427177e-19 514.03591788434 144.4449484171 3.55869778429361 0.000413528818055123 -174.570312249892 179.351905528948 -0.973339601466991 0.330923000701091 MBOAT7 other 6.18396212133149e-15 1 1 3.55869778429361 -0.973339601466991 0.000697903797154049 272.355948709624 79.1457279289444 3.4411958274506 0.000634986631716026 -185.953633068226 185.6957660669 -1.00138865310065 0.317194377459066 MED1 essential 1 1 1 3.4411958274506 -1.00138865310065 0.000482875325902109 2603.68263392254 734.63823515949 3.54416978222932 0.000436318139072165 -1712.22129267308 1723.64412298885 -0.993372860346622 0.321077996273985 RPL23 essential 1 1 1 3.54416978222932 -0.993372860346622 1.93617729711727e-31 76.1112153067814 30.2920501926869 2.51258052269952 0.0123434654636204 -181.367484996699 38.8979438776445 -4.66264966516482 4.15091686253854e-06 ATG4C other 1.76114686945787e-27 0.0357684506044946 1 2.51258052269952 -4.66264966516482 0.299711297707114 -247.661515315686 401.583036482743 -0.616713089987129 0.537745869642633 -595.858774232687 492.686723121806 -1.20940700503791 0.227161893305397 FOSB other 1 1 1 -0.616713089987129 -1.20940700503791 3.92525444211382e-23 225.936346276259 37.2836213068537 6.05993565959555 2.94313623484843e-09 55.8626670910259 45.735511848865 1.22142870677006 0.222582263054504 OPA3 other 3.4385228912917e-19 1 2.7612504155348e-05 6.05993565959555 1.22142870677006 5.42180564555461e-46 1008.28909728071 138.9660787639 7.25564904938976 1.83691955568964e-12 -65.0229156447007 170.391878726348 -0.381608068006155 0.702937578661762 SNRPD2 essential 5.13607648803388e-42 1 1.76656553670673e-08 7.25564904938976 -0.381608068006155 0.00986173025261694 -74.5185909047575 52.2777993654465 -1.42543473155474 0.154747067377913 -0.353942225188459 64.1376136974549 -0.00551848135258116 0.995599435310215 RTN2 other 1 1 1 -1.42543473155474 -0.00551848135258116 2.80038082926333e-32 168.21120305538 64.7401684893994 2.59825093107262 0.00968659005494853 -291.94782940802 79.4162326313553 -3.6761732423549 0.000266212089635992 VASP other 2.55646765903449e-28 1 1 2.59825093107262 -3.6761732423549 7.21165054747818e-43 436.022406110761 134.367777276294 3.24499232590705 0.00126477709422635 -696.825658816042 164.827848109162 -4.22759665195985 2.87791737541072e-05 SYMPK essential 6.78183617484848e-39 0.238118883641483 1 3.24499232590705 -4.22759665195985 0.0927176311673154 230.739017272656 120.237971435299 1.91901954530909 0.0556358647907593 509.275021689408 324.927489568762 1.56734975660357 0.117760080227533 CD93 other 1 1 1 1.91901954530909 1.56734975660357 0.00682165467053066 77.1138747678695 40.0836800489772 1.92382223073446 0.055029063442525 -200.299098724448 108.320935354436 -1.84912637680842 0.0651178169295796 GZF1 other 1 1 1 1.92382223073446 -1.84912637680842 0.199287787356928 -26.5108998965962 18.1965930856985 -1.45691557599496 0.145861133726386 28.7777490544923 49.4633431193337 0.581799515351479 0.561003107305852 PAX1 other 1 1 1 -1.45691557599496 0.581799515351479 0.224197166433686 -437.507503459548 499.264792902382 -0.87630353607788 0.381348691490637 -2274.8398497157 1349.19820961162 -1.68606794280474 0.0924997663920213 NAPB other 1 1 1 -0.87630353607788 -1.68606794280474 0.852046648280001 -38.5275962326972 71.2224394552377 -0.540947439141161 0.58882134407492 -61.5713291703196 193.598767872383 -0.318035749126804 0.750610791784573 NKX2-2 other 1 1 1 -0.540947439141161 -0.318035749126804 0.0137328090863314 0.52023272447181 2.62601100346524 0.19810759505018 0.843052795321682 20.7325456646124 7.30125250714303 2.83958754259344 0.00472751388778032 S1PR4 other 1 1 1 0.19810759505018 2.83958754259344 3.61348440008359e-14 557.763259242958 75.2164528996469 7.41544220367744 6.3273162136686e-13 -163.244443221829 209.128718267848 -0.780593141745114 0.435463480992235 NCLN other 2.86838391678635e-10 1 6.09700190349106e-09 7.41544220367744 -0.780593141745114 8.49587738115366e-39 448.007400142421 161.594480230997 2.7724177181176 0.00580312418492298 -1102.25138853434 206.741226699115 -5.33155097381 1.56785795372161e-07 HNRNPR other 7.9062634909016e-35 0.00141499180323375 1 2.7724177181176 -5.33155097381 1.57780073818681e-23 163.241685364806 92.0111241777532 1.77415162376937 0.0767342909975805 -495.766897412767 117.618277726419 -4.21504979494704 3.03601796097113e-05 ZNF436 other 1.38530904812802e-19 0.250775083576215 1 1.77415162376937 -4.21504979494704 2.2709770454261e-33 -58.4943310657628 77.2318304198631 -0.757386310123226 0.449225708286564 -665.347586653714 87.8188540028618 -7.57636380260703 2.13284761375287e-13 MAX other 2.08203175524665e-29 2.05649166918052e-09 1 -0.757386310123226 -7.57636380260703 1.78527697867522e-13 -195.53464641671 95.7658146295415 -2.04180006376087 0.0417699386429008 -622.318869075874 108.893496990768 -5.71493143551663 2.03134980613444e-08 CHURC1-FNTB other 1.39751481890696e-09 0.000186741987677939 1 -2.04180006376087 -5.71493143551663 2.23787080412785e-11 304.438920167992 72.4510016249483 4.20199739603268 3.21203971615506e-05 -232.032100305049 109.654063802087 -2.11603740216907 0.034909150919935 TMEM115 other 1.67325600024639e-07 1 0.273151857461827 4.20199739603268 -2.11603740216907 7.12282208877703e-79 461.454648615422 80.6406062802455 5.72236085393203 1.95038426253289e-08 -770.112540955904 103.550395479851 -7.43707966915254 5.47213768787613e-13 PSMB2 essential 6.9896253157169e-75 5.2658380970432e-09 0.000180644590395796 5.72236085393203 -7.43707966915254 4.51310646851305e-58 80.9632145502676 55.7157070061676 1.45314883182412 0.146898494282093 -639.207733770431 71.5443963166417 -8.93442067693772 1.14466800115807e-17 AGO3 other 4.35830691664305e-54 1.11982870553294e-13 1 1.45314883182412 -8.93442067693772 5.84115546833869e-64 443.475983037911 78.8148922534918 5.62680440660329 3.280217013746e-08 -586.15473588248 101.693032840295 -5.76396159610082 1.55190866823702e-08 UROD essential 5.6740984219442e-60 0.000142946307431312 0.000302567217347931 5.62680440660329 -5.76396159610082 1.18958113758266e-56 117.466093091195 28.2642940922435 4.155988920432 3.89657142200865e-05 -230.215722736172 36.4687650410754 -6.312682167243 6.731663731265e-10 ST3GAL3 other 1.14711309097096e-52 6.32035907728471e-06 0.329961668015693 4.155988920432 -6.312682167243 6.46253856932132e-36 27.6534150358959 22.5088422730629 1.22855785741543 0.219897321889937 -187.762408188213 29.0426386565312 -6.4650602312262 2.70613789649799e-10 TMEM53 other 5.97073938419597e-32 2.55107619502865e-06 1 1.22855785741543 -6.4650602312262 7.8702574958648e-65 111.136603162435 45.4240818184636 2.44664501104481 0.0148114370938068 -521.420723305948 58.6096423154167 -8.89650069010562 1.52922366574934e-17 HECTD3 other 7.65382541472852e-61 1.49573366746943e-13 1 2.44664501104481 -8.89650069010562 4.33810160001988e-07 -125.383500898333 592.185231885108 -0.211730205596649 0.832416914335368 -2479.57523860493 687.822921184519 -3.60496162927339 0.000348427433961953 KLC1 other 0.00269439490377235 1 1 -0.211730205596649 -3.60496162927339 0.000289859520367655 76.1309683091875 50.7164283572893 1.50111060212791 0.134054113039799 -70.4961071396702 58.9071122116805 -1.19673337383006 0.23206380625743 XRCC3 essential 1 1 1 1.50111060212791 -1.19673337383006 1.53122389543403e-26 289.251252254059 41.9273298916559 6.89887128518586 1.85809927937217e-11 -189.897415347627 61.3300750215263 -3.09631800190974 0.00208610201050707 TUBGCP3 essential 1.36585171472715e-22 1 1.77615710115186e-07 6.89887128518586 -3.09631800190974 0.00329463411244546 -247.078136930513 177.419053662794 -1.39262459036736 0.164451327095873 -843.079155001267 256.108342867099 -3.29188477643137 0.00107708398875117 MCF2L other 1 1 1 -1.39262459036736 -3.29188477643137 0.125507373198404 1.66834405390269 2.36477374029879 0.705498384675016 0.480882140479886 -3.53735227394876 3.39004074179428 -1.04345420700652 0.297324242101832 F10 other 1 1 1 0.705498384675016 -1.04345420700652 7.10282393284344e-27 207.274443746713 29.957380071109 6.91897766943276 1.65821430236188e-11 -130.996396304657 42.9456472844813 -3.05028343005075 0.00242767460068952 PCID2 essential 6.34921431356875e-23 1 1.58558451591843e-07 6.91897766943276 -3.05028343005075 6.37424287455317e-28 121.271016495849 28.5013661700388 4.25491942289178 2.56268241436696e-05 -92.3888505636495 37.4811453114807 -2.46494203407788 0.0140888708262461 LRFN3 other 5.72534494992365e-24 1 0.218878705011082 4.25491942289178 -2.46494203407788 9.07859964435949e-32 80.370884953214 25.1598914306546 3.19440507820677 0.00150309839122456 -135.910321266513 33.2402287589373 -4.0887300220511 5.16740357062962e-05 IGFLR1 other 8.26788069611818e-28 0.420419954506426 1 3.19440507820677 -4.0887300220511 1.80946346001198e-52 1840.56171811767 261.514327422473 7.03809132087922 7.60857564411597e-12 -970.709972545627 343.842092073638 -2.82312722881449 0.00497352945973527 CAPNS1 other 1.73491356545949e-48 1 7.29510232757839e-08 7.03809132087922 -2.82312722881449 8.71955779835177e-57 38.8502909188127 8.15559909642061 4.76363421736407 2.5932763015094e-06 -61.9940139884141 10.7673048127316 -5.75761669857346 1.61155111170829e-08 PDCD2L other 8.40914154073044e-53 0.0001483916263661 0.0229945809654838 4.76363421736407 -5.75761669857346 2.63667651806538e-58 855.61717895447 93.1440505134811 9.18595631430729 1.65409940704371e-18 -162.348614086443 124.005762298663 -1.3092021780039 0.191153836332669 RBM42 essential 2.54702951645116e-54 1 1.61440102127466e-14 9.18595631430729 -1.3092021780039 0.0149194040442959 21.8847280170609 10.3178262525281 2.12105994823267 0.0344818146118352 38.8395542878121 13.5686108084232 2.86245621133897 0.00440670958421256 KIRREL2 other 1 1 1 2.12105994823267 2.86245621133897 6.11600970841044e-67 254.03606106217 141.649685862493 1.79341069142063 0.0736001811374331 -1824.84842746534 187.010828545819 -9.75798268824973 1.77559618335264e-20 UBA2 essential 5.95760505696261e-63 1.74221497510561e-16 1 1.79341069142063 -9.75798268824973 3.09838329850892e-19 11.4757948488193 20.3783176001629 0.563137501043147 0.573631395348275 -126.716774781579 26.7988095243706 -4.72844790610358 3.06145500210662e-06 HCST other 2.62928806711467e-15 0.0265060774082391 1 0.563137501043147 -4.72844790610358 1.90164946946271e-33 988.229098142028 151.61833685613 6.51787322452796 1.96970530257293e-10 -170.545396183691 201.854518207564 -0.84489263702446 0.398633106595212 COX6B1 other 1.7438125634973e-29 1 1.86905336161145e-06 6.51787322452796 -0.84489263702446 0.000661741946776339 -281.88935686591 852.548367527927 -0.330643242779626 0.741072084994238 -7096.15857734992 1867.29556733258 -3.8002331829485 0.000165016008236179 THRA other 1 1 1 -0.330643242779626 -3.8002331829485 0.0467418435960217 -199.987364620943 161.299176943602 -1.23985359634456 0.215693391826804 -847.385078219014 353.285807108552 -2.39858228428249 0.0168759778823189 NR1D1 other 1 1 1 -1.23985359634456 -2.39858228428249 2.08463603934493e-59 132.885804009368 13.7816501341725 9.64222736142961 4.43433789709133e-20 13.9910745165046 16.8239414399159 0.831616929152516 0.406078342829732 BCL2L12 other 2.01605151365048e-55 1 4.33545216198619e-16 9.64222736142961 0.831616929152516 5.6839685912801e-61 457.326437966742 62.5987908568992 7.30567526475375 1.31529930836636e-12 -148.264034997275 76.4174377765285 -1.94018589619363 0.0529985674503608 IRF3 other 5.50719716809129e-57 1 1.26597558430262e-08 7.30567526475375 -1.94018589619363 2.01687998419999e-51 945.526951142272 149.02541207202 6.34473636405933 5.56524916921604e-10 -349.010206360195 181.92268569801 -1.91845346291528 0.0557032704179608 PRMT1 essential 1.93015414487939e-47 1 5.25971698982608e-06 6.34473636405933 -1.91845346291528 5.25007232455121e-18 117.990538952144 42.7711991145862 2.75864463458322 0.00604724909022853 -87.0089325536524 52.212916611091 -1.66642544031279 0.0963436152107439 RRAS other 4.39116049225463e-14 1 1 2.75864463458322 -1.66642544031279 3.63667658739509e-19 7.74580963637877 2.0424664441286 3.79238036377311 0.000170151384791574 -1.85300320435239 2.49220449388341 -0.743519726772098 0.457565721409857 PRRG2 other 3.08426541376978e-15 1 1 3.79238036377311 -0.743519726772098 4.55763258078966e-31 584.539475924644 147.387447570269 3.96600582723271 8.5356822564967e-05 -378.769461047858 179.923141478716 -2.10517367546445 0.0358450898709544 SCAF1 other 4.14015343638932e-27 1 0.71213197065952 3.96600582723271 -2.10517367546445 4.79260864793277e-26 69.2937650056703 81.7691427516242 0.847431716584724 0.397217348293454 -455.388107407464 99.819633777697 -4.56210957877921 6.58427353918739e-06 PRR12 other 4.26590095752496e-22 0.0562296960246603 1 0.847431716584724 -4.56210957877921 0.232848621427913 48.6004144939168 52.7531939586424 0.921279089414352 0.357411887251548 188.232517716272 115.542776214843 1.629115414072 0.104007553653257 STAT5A other 1 1 1 0.921279089414352 1.629115414072 0.746609921111174 -0.29830675065885 11.7867660245814 -0.0253086173117145 0.979820353157371 -19.2365076173881 25.8162818483054 -0.745130833728127 0.456593184454311 WNK4 other 1 1 1 -0.0253086173117145 -0.745130833728127 3.42065246201768e-09 229.313362819998 49.993414445541 4.58687139822774 5.8851230411327e-06 -341.022148505561 109.499422928527 -3.11437393353347 0.00196461892127803 BECN1 other 2.38214237454911e-05 1 0.051530137348158 4.58687139822774 -3.11437393353347 0.11430403853251 -165.757600312955 182.878412721083 -0.906381446812754 0.365236924239126 11.5370539554177 225.935750797319 0.0510634280529039 0.959298471188247 PRKCG other 1 1 1 -0.906381446812754 0.0510634280529039 2.08740034303886e-98 423.895566333048 73.2441370767723 5.78743341448249 1.36527789968249e-08 -920.642941366386 94.0872610974084 -9.78499034437026 1.413419054347e-20 DNAJC8 essential 2.05588059785897e-94 1.38741214374702e-16 0.000126752400206522 5.78743341448249 -9.78499034437026 2.86493271798522e-29 0.606901856583208 106.996983946261 0.00567213985104499 0.995476899833251 -907.684154400188 137.435975041912 -6.60441455829437 1.1612959845952e-10 AHDC1 other 2.58502879143806e-25 1.09707631664708e-06 1 0.00567213985104499 -6.60441455829437 0.000380267310912648 1406.92749729032 1194.65952506226 1.17768072641199 0.239564872889039 -1606.36559386032 1534.52172775733 -1.04681840915214 0.29576198532395 IFI6 other 1 1 1 1.17768072641199 -1.04681840915214 1.04883397806699e-20 117.597646252748 132.785550938259 0.885620803030197 0.376307842596156 -745.462124418113 153.122510999934 -4.86840321223858 1.57343063431147e-06 PCNX4 other 9.02416754728838e-17 0.0137879726484714 1 0.885620803030197 -4.86840321223858 2.94389636104017e-23 96.4789497424219 51.5571701087639 1.87130033589687 0.0619744657303658 -337.371020582581 64.1812313343874 -5.2565370524735 2.30538209634699e-07 ATG14 other 2.58091393972392e-19 0.00207369119566412 1 1.87130033589687 -5.2565370524735 5.70056866605572e-14 -205.176953433321 365.138315831312 -0.561915703002009 0.574463526418795 -2464.21650595381 452.023729471237 -5.45152023066658 8.3946640170974e-08 KTN1 other 4.50629953051704e-10 0.000763494692355008 1 -0.561915703002009 -5.45152023066658 0.00632691084481736 16.0357657101727 63.4539325716676 0.25271508100875 0.800606949574868 -111.626478453152 72.8943200781621 -1.5313467267883 0.126405633345708 SIX1 other 1 1 1 0.25271508100875 -1.5313467267883 0.235764978584397 -82.1750281574986 127.559486528506 -0.644209461748931 0.519776823140773 -198.997312888414 145.173199137797 -1.37075792274529 0.171152441376099 RHOJ other 1 1 1 -0.644209461748931 -1.37075792274529 0.0335844886264276 95.4278422714431 36.8120513181804 2.59229895793158 0.00985464277851096 102.32850224343 45.8256878056204 2.23299435629812 0.0260573038372042 DLGAP5 other 1 1 1 2.59229895793158 2.23299435629812 5.23173113813667e-09 51.9481917188952 37.3258342680393 1.39174897862569 0.164704771148545 -100.78375543683 43.4282479890511 -2.3206958627997 0.0207616874328613 L3HYPDH other 3.61669573579388e-05 1 1 1.39174897862569 -2.3206958627997 0.0205726768456473 -1323.01052048728 688.333841785868 -1.92204776254318 0.055248138097757 -2112.13368137955 782.691395871352 -2.69855231898667 0.0072333800975736 HSPA2 other 1 1 1 -1.92204776254318 -2.69855231898667 1.04695203445896e-18 79.1113220481991 60.7087212944436 1.303129441065 0.193215196077689 -261.373140175229 69.0307390498673 -3.78632973908066 0.000174210704297037 ZBTB1 other 8.83941602693702e-15 1 1 1.303129441065 -3.78632973908066 5.68242089233084e-19 104.071071252688 82.0784335206815 1.26794660654026 0.205495247695534 -391.663344651509 94.3188934730776 -4.15254388839183 3.95835040449486e-05 TRMT5 essential 4.80903280117959e-15 0.324109731120039 1 1.26794660654026 -4.15254388839183 9.05064692202916e-11 -50.6817144915356 51.3303504159202 -0.987363500947708 0.324009582129244 -259.577500300154 58.4181654029942 -4.44343807289178 1.12286223853866e-05 SGPP1 other 6.67032678153549e-07 0.0948594019117457 1 -0.987363500947708 -4.44343807289178 1.32341202387712e-06 -334.078125823974 192.412064811311 -1.73626391958108 0.0832203399486304 -890.740667917225 218.788120599921 -4.07124786060046 5.54912070498498e-05 PLEKHG3 other 0.00793517849516723 0.44970939120313 1 -1.73626391958108 -4.07124786060046 4.80013120814766e-05 115.437654897519 45.2057206490188 2.55360722581523 0.0109998375267387 -262.878758907759 93.020500628192 -2.82603036032347 0.00492899043335591 RHOT1 other 0.247350761155849 1 1 2.55360722581523 -2.82603036032347 0.717507043484649 -122.908510638296 150.874302385436 -0.8146417825635 0.415723141115478 -77.2390070921976 322.298738574893 -0.239650354927621 0.810714205134581 EVI2A other 1 1 1 -0.8146417825635 -0.239650354927621 0.00538060311938798 1289.65728411983 398.152903715363 3.2391005367169 0.00129035034313345 831.109653416875 858.376230450753 0.968234701676723 0.333461498380805 AIF1L other 1 1 1 3.2391005367169 0.968234701676723 0.408986055279526 -16.6289926289933 32.1082372809547 -0.517904252528275 0.604787160636331 62.6369778869774 67.6596681861939 0.925765371988015 0.355078880528154 FAM78A other 1 1 1 -0.517904252528275 0.925765371988015 7.87758489575935e-06 403.460114660115 88.9057736713916 4.53806426735975 7.34746162340878e-06 14.8863226863232 187.345542946117 0.0794591771558968 0.936703773885732 NUP214 essential 0.0442483943594802 1 0.0641359925107352 4.53806426735975 0.0794591771558968 5.16654370434101e-12 868.374605019092 124.383913237427 6.98140605498977 1.08886687838373e-11 -69.0436972387814 330.12096622927 -0.209146659260746 0.834430986387681 MAP2K2 other 3.91985670848352e-08 1 1.04259003605242e-07 6.98140605498977 -0.209146659260746 1.34379855659111e-05 660.228454542052 1180.09983699091 0.559468304161062 0.576129435930814 -9266.98791329633 2321.41806737316 -3.99195131783503 7.68814490234186e-05 CANX other 0.0737378961287145 0.616896746963911 1 0.559468304161062 -3.99195131783503 9.35182799869067e-13 111.245832534968 16.8253822136992 6.61178635480814 1.11247817109211e-10 -35.5477102893277 34.8055522488157 -1.02132297844914 0.307667796431092 IPPK other 7.20558347299116e-09 1 1.05785549289148e-06 6.61178635480814 -1.02132297844914 0.00100205614442684 28.2366353707606 10.4390709028683 2.70489928016506 0.00710011685668516 -28.6702433416365 21.5946136096122 -1.32765715839782 0.184986083829045 ZNF484 other 1 1 1 2.70489928016506 -1.32765715839782 0.236256710114139 -6.34913690120704 8.08937613249325 -0.784873492988409 0.432953022091917 -28.3866354079564 16.7335913025179 -1.69638632226456 0.0905248861478291 OMD other 1 1 1 -0.784873492988409 -1.69638632226456 0.82299060027363 6.4953056141024 35.3902465338172 0.183533776965803 0.85446453953378 45.4634987545509 73.2094557607334 0.621005828852722 0.534920296382045 FGD3 other 1 1 1 0.183533776965803 0.621005828852722 1.24842583752369e-13 -57.3138711618878 48.1633208738631 -1.18999001983251 0.234694923136386 -323.619084801258 61.8500156838535 -5.23232017361867 2.60084050831664e-07 HIVEP3 other 9.81637236044879e-10 0.00233659511267167 1 -1.18999001983251 -5.23232017361867 3.14919954904476e-29 -25.8680456002635 34.9743495295566 -0.739629069538594 0.459921319080804 -325.289519028478 44.913100419318 -7.24264225786035 1.99488599194682e-12 PPCS other 2.84120783314818e-25 1.91449208647136e-08 1 -0.739629069538594 -7.24264225786035 0.0245588229697532 -2.77891262241873 28.9163935358275 -0.0961016324174606 0.923483808857497 -58.8453719616992 34.2304126299678 -1.71909619080027 0.0863033945084235 BCL11B og 1 1 1 -0.0961016324174606 -1.71909619080027 5.55976238617663e-14 158.397009318936 19.8678600369326 7.97252492339338 1.37663274968136e-14 79.2738772117082 41.8670207704047 1.89346831355495 0.0589574317265849 TRAF2 other 4.39610411874986e-10 1 1.33381947116627e-10 7.97252492339338 1.89346831355495 0.00392650983503846 133.754342045882 407.111516079376 0.328544727336585 0.742657206621873 -2480.52936420325 862.429006172832 -2.87621282035839 0.00422168590098425 MASP1 other 1 1 1 0.328544727336585 -2.87621282035839 0.0171468406125212 -96.2726272606701 108.660586806581 -0.885993993682714 0.37610916177007 -553.855013828769 198.835474525548 -2.78549396253537 0.00557760326572069 ATP13A4 other 1 1 1 -0.885993993682714 -2.78549396253537 0.080007198440976 59.7836447384092 29.3165477227112 2.0392457291994 0.0420293754361758 11.9260449029522 54.5318715979944 0.218698617037578 0.826987394325053 HRASLS other 1 1 1 2.0392457291994 0.218698617037578 0.124934313655374 18.5653317360337 10.0677009798339 1.84404878265861 0.0658543206980415 28.8565581314089 16.3877263373288 1.76086404772808 0.0789624041257126 HELB other 1 1 1 1.84404878265861 1.76086404772808 0.0670625763531526 120.034705021393 60.6000177080474 1.98077013111917 0.0482464966129964 8.14626022667623 98.6474498214668 0.0825795318725362 0.934223861535727 RAP1B other 1 1 1 1.98077013111917 0.0825795318725362 0.925223338357363 -0.0171382409101035 7.22248471768247 -0.00237290095860566 0.998107786036884 3.88073333244316 12.0323596707944 0.322524711579449 0.747209820464597 TSPAN8 other 1 1 1 -0.00237290095860566 0.322524711579449 0.00273699933994807 216.712935318727 185.465823516304 1.16847908261478 0.243252071434841 -619.276654156561 301.89247443885 -2.05131530790112 0.0408332206401618 BEST3 other 1 1 1 1.16847908261478 -2.05131530790112 0.000153160077924629 75.8293166864775 464.991714612113 0.163076705032761 0.870533599247884 -2589.7918082242 756.891467421618 -3.42161580582541 0.000681213464030118 RAB3IP other 0.742366897700675 1 1 0.163076705032761 -3.42161580582541 0.0945950819188294 -135.80563796831 128.98804604223 -1.05285444764275 0.292990843200599 -455.492470541986 209.960625922533 -2.16941852092804 0.0305905182363341 PTPRB other 1 1 1 -1.05285444764275 -2.16941852092804 9.64223878542612e-05 88.7127481351839 45.4111150848613 1.95354701088937 0.051393944697101 -157.773748132063 73.9180601583504 -2.13444113379158 0.0333638401211677 DYRK2 other 0.478737155696407 1 1 1.95354701088937 -2.13444113379158 3.27041380239712e-08 53.7686879369567 22.7461999595778 2.36385365610559 0.0185235693209407 -120.367213554583 37.0251858789183 -3.2509550106842 0.00123937541925729 YEATS4 essential 0.000217024659927073 1 1 2.36385365610559 -3.2509550106842 0.0237207799566286 35.1162732062046 44.9443780447644 0.781327381396376 0.435037938868422 -115.328388868985 69.8902614120802 -1.65013531984087 0.0996420906835134 IDUA other 1 1 1 0.781327381396376 -1.65013531984087 0.321049024778512 140.490233846366 160.207371800836 0.876927398952766 0.381008990652235 -115.708994111139 249.059948376128 -0.464582904098239 0.642462084506817 FGFRL1 other 1 1 1 0.876927398952766 -0.464582904098239 0.0174121943973144 -105.535743195725 120.830143618771 -0.873422310319341 0.382918176887997 -508.713842111552 187.89558764311 -2.70742835684787 0.00704963883291262 TMEM175 other 1 1 1 -0.873422310319341 -2.70742835684787 5.6283871655415e-78 41.7167588689164 8.98722604114988 4.64178364691258 4.57114980058201e-06 -96.0747761113459 11.5390512915958 -8.32605503550535 1.07797227866553e-15 AUNIP other 5.51975929324655e-74 1.0490826215973e-11 0.0402169759455206 4.64178364691258 -8.32605503550535 1.46172238013451e-47 218.770451549574 87.7835686537212 2.49215718732688 0.0130656695946383 -749.015886106343 112.17141468415 -6.67742212412498 7.38763095997124e-11 EMC1 essential 1.3887824333658e-43 6.99756404528476e-07 1 2.49215718732688 -6.67742212412498 0.000117387224767574 -22.4890864800877 76.6339874104096 -0.293460998703466 0.769309439186218 -248.203722166535 98.0056698378278 -2.53254452091643 0.0116736296572967 PLA2G5 other 0.576958209732624 1 1 -0.293460998703466 -2.53254452091643 5.17439893972041e-28 -12.1688071165305 252.324267579537 -0.0482268599578702 0.961557426297683 -2083.72979430843 322.424463799 -6.46269135336898 2.74510696144309e-10 UBR4 other 4.65023232712674e-24 2.58753782185625e-06 1 -0.0482268599578702 -6.46269135336898 1.24748110521156e-78 981.746236726742 225.163070614906 4.36015654807716 1.62250896498188e-05 -2515.42509356736 289.226916401492 -8.69706431498082 6.96318396472395e-17 HP1BP3 other 1.22390371232306e-74 6.79467491277763e-13 0.139714246974589 4.36015654807716 -8.69706431498082 0.00287021628847069 14.7516964205846 5.83725687394571 2.52716245646615 0.0118497578283344 -3.33386579428251 9.29476453412621 -0.358682114220542 0.720005733126282 METTL25 other 1 1 1 2.52716245646615 -0.358682114220542 0.000512578510530284 89.8256153856795 23.0219511288505 3.90173773208616 0.000110518382865735 -11.3534943264276 16.7775592694196 -0.67670715055208 0.498948987212526 EMC6 other 1 1 0.916528949105543 3.90173773208616 -0.67670715055208 8.14591588832931e-05 169.888346212472 58.4528713973605 2.90641575257403 0.00384141411440529 -156.771557151082 44.8694586932063 -3.49394803763966 0.000524370600445331 METTL16 other 0.408110386005299 1 1 2.90641575257403 -3.49394803763966 0.047734615801012 69.2282803320989 159.492950428772 0.434052289746911 0.664465175074474 -246.450512670437 196.188582710817 -1.25619192139078 0.209719072603546 TNFRSF19 other 1 1 1 0.434052289746911 -1.25619192139078 1.10750666612109e-06 2.79082270483138 53.9959787311271 0.0516857508728247 0.958802762287618 -231.724212170891 66.4388246271246 -3.48778313691428 0.000536505407570351 RNF6 other 0.00668601774337304 1 1 0.0516857508728247 -3.48778313691428 3.79074999382805e-13 428.654397929552 157.960615702521 2.71367895106724 0.00692273958171037 -219.153526512733 179.218731651951 -1.22282712578469 0.222067897983563 ECHS1 other 2.94730812020131e-09 1 1 2.71367895106724 -1.22282712578469 1.30597136371869e-42 43.1563738692949 10.1304346673345 4.26007128879201 2.5043581772444e-05 -38.5384595394957 12.712890267778 -3.03144750939722 0.00257855256070415 ZNF835 other 1.2274824847592e-38 1 0.213997406245534 4.26007128879201 -3.03144750939722 1.00254525473489e-15 110.442264573094 27.5350157930876 4.01097516714771 7.11445991788469e-05 -38.5900427939892 37.8938882724573 -1.0183711557 0.30906635494434 ZNF780B other 8.15470310201358e-12 1 0.595693728924485 4.01097516714771 -1.0183711557 4.7608512746488e-06 22.7217368362048 22.7208859281196 1.00003745048005 0.317844534166322 -66.5856992213871 32.1442807132889 -2.07146334414196 0.0389004354268422 LRFN1 other 0.0273368080190334 1 1 1.00003745048005 -2.07146334414196 4.62129175925215e-06 110.413230260103 416.374909748321 0.265177434266734 0.79099753185719 -1605.53169198401 589.06470563087 -2.72556083675821 0.00667651724450042 ZFP36 other 0.0265724276156998 1 1 0.265177434266734 -2.72556083675821 0.765350604985001 8.2532038798935 25.8577248927643 0.319177495859389 0.74974985305333 -17.3175782191811 44.6749687024492 -0.387634926719751 0.698481657765789 SRD5A3 other 1 1 1 0.319177495859389 -0.387634926719751 0.79083598274292 -5.7589141692843 93.7291414764826 -0.0614420881122576 0.951036642079371 -99.0254053824599 161.573847940567 -0.612880157554242 0.540290484454375 RASL11B other 1 1 1 -0.0614420881122576 -0.612880157554242 6.88892085851756e-06 963.549423172962 229.686662699999 4.19506040031364 3.3211230849892e-05 -35.287730751978 424.128478880942 -0.0832005689527954 0.933731140944645 PAICS essential 0.0388810693254731 1 0.282129406069832 4.19506040031364 -0.0832005689527954 0.383700569520138 -105.700248399258 96.2343724567685 -1.09836273361415 0.272673882606065 26.4141340168445 169.600610666857 0.15574315394848 0.876310128011299 KDR og 1 1 1 -1.09836273361415 0.15574315394848 8.79826237334814e-09 155.032693919124 27.5869830996131 5.61977702887337 3.46041570987308e-08 30.4092636532667 50.9408123284696 0.596952860845363 0.550855976909025 PPAT essential 6.02768955198081e-05 1 0.000319050328450298 5.61977702887337 0.596952860845363 1.74324972165908e-10 428.235065565811 143.735591524959 2.97932516937845 0.0030498554187445 -550.444519257651 210.108073169699 -2.61981613059233 0.00910395428656664 TUBGCP6 essential 1.27326959669979e-06 1 1 2.97932516937845 -2.61981613059233 8.37281634796988e-08 215.859165796535 72.6126016598273 2.97275074659607 0.00311459919627939 -288.867884190909 121.61838888936 -2.37519907004935 0.0179700932361423 DGCR6L other 0.000542893412002367 1 1 2.97275074659607 -2.37519907004935 0.659373696122033 21.8905041549762 31.8466631004551 0.687371988893345 0.492213813548394 -4.84523801552184 51.466965911303 -0.0941426783127651 0.925039066121147 ASPHD2 other 1 1 1 0.687371988893345 -0.0941426783127651 0.127054448260532 40.664330440216 23.534114219045 1.72788871770277 0.0847162566989895 3.54952256767589 38.6313271372501 0.0918819732768972 0.926834014466613 SDF2L1 other 1 1 1 1.72788871770277 0.0918819732768972 0.0128669808596959 -70.0570566037722 64.3564023833815 -1.08857944212654 0.276939356664575 -293.385808176099 102.314474340962 -2.86749074425572 0.0043375696808943 GAL3ST1 other 1 1 1 -1.08857944212654 -2.86749074425572 0.700137194738064 -303.424901941138 806.594088070535 -0.376180418910538 0.706965332014638 -1077.38676828305 1292.57196372469 -0.833521690489428 0.40500591661901 YWHAH other 1 1 1 -0.376180418910538 -0.833521690489428 0.0499924771890797 0.542830210910576 27.0731912120943 0.0200504701000331 0.984012241802322 -88.0222497152509 44.0419408390833 -1.9986006074723 0.0462691818565898 RFPL1 other 1 1 1 0.0200504701000331 -1.9986006074723 0.0598012617809838 -5.04172240342298 4.22452404228647 -1.19344152215884 0.233343995408274 -16.0402762167888 6.76982563832391 -2.36937804217364 0.0182517151251458 RFPL2 other 1 1 1 -1.19344152215884 -2.36937804217364 0.0552525429691336 17.4803018867923 11.7099286923565 1.49277611726213 0.136217389179335 -12.0228286163522 18.6165657861259 -0.645813452087512 0.518739139221454 POM121L9P other 1 1 1 1.49277611726213 -0.645813452087512 0.000154874724269063 382.209895666775 121.191834108716 3.15375947956948 0.00172272742223483 -94.7553965462094 195.82394674279 -0.483880537198386 0.628712486043855 GNAZ other 0.750213164359343 1 1 3.15375947956948 -0.483880537198386 6.73802796307747e-08 -33.2855340350343 117.208135465244 -0.283986550105171 0.77655488514726 -861.650224311974 181.123995186286 -4.75723950007709 2.66892054680311e-06 MGAT3 other 0.000438578240116712 0.023166230346251 1 -0.283986550105171 -4.75723950007709 0.517880758420644 10.2141886792458 14.79214235639 0.690514492975616 0.490237281220965 -7.76961163521955 23.516700957814 -0.330386972609689 0.741265918242654 ADORA2A other 1 1 1 0.690514492975616 -0.330386972609689 1.38856043571642e-12 2041.31247303944 304.700142863852 6.69941423017828 6.44622514714332e-11 618.888922439827 470.859014950358 1.31438265550693 0.189405333982637 ATF4 essential 1.06572013441235e-08 1 6.14260794271287e-07 6.69941423017828 1.31438265550693 0.789928555005416 -6.8076877846852 17.4371086193643 -0.390413796994136 0.696420824872079 4.45112750516814 25.8598901773004 0.1721247644383 0.863419126293113 A4GALT other 1 1 1 -0.390413796994136 0.1721247644383 0.000275868083956775 7.65790317513277 2.47997818871387 3.08789134113482 0.00214424421186184 -1.45611722371029 3.97418022868024 -0.366394360578318 0.71424815004293 RFPL3 other 1 1 1 3.08789134113482 -0.366394360578318 0.0121103816206905 155.705378345331 230.484474091851 0.675556906636931 0.499680965289832 -661.621012090754 356.283018209174 -1.85700967566834 0.0639855000868062 CDC42EP1 other 1 1 1 0.675556906636931 -1.85700967566834 0.360240170687382 -30.2371884073534 38.1046898889867 -0.793529313463663 0.427901133549021 -84.6001195656741 59.2832220807555 -1.42704995775081 0.154281237750222 APOL3 other 1 1 1 -0.793529313463663 -1.42704995775081 0.484613402538444 -17.873484352696 70.0899866096602 -0.255007672525829 0.798837140245831 -114.805371046949 107.034879112806 -1.07259775503604 0.284043587133803 MCHR1 other 1 1 1 -0.255007672525829 -1.07259775503604 0.000506482636045029 -30.7986594258693 60.7433190348565 -0.507029578153213 0.612390401385442 -341.136826281145 98.1664647327424 -3.47508517506347 0.000561828230410807 TPST2 other 1 1 1 -0.507029578153213 -3.47508517506347 0.419318631719266 3.9265092253717 9.63159989681066 0.407669470019399 0.683715993806284 -10.8543686040035 14.885434725666 -0.729193927086859 0.466273675176551 BAIAP2L2 other 1 1 1 0.407669470019399 -0.729193927086859 4.14916518657438e-10 510.59703423567 99.5009808727205 5.13157789759695 4.32670330618509e-07 -43.2311128803967 154.744202251844 -0.279371454641246 0.780091645321756 MPST other 2.99860168033731e-06 1 0.00391263779978317 5.13157789759695 -0.279371454641246 0.0103465351511707 117.517068073248 77.5496970321229 1.5153775265501 0.130398137226718 -137.731179228593 120.605504557374 -1.14199745471048 0.25407899066292 TST other 1 1 1 1.5153775265501 -1.14199745471048 0.15626633721508 410.060674365026 292.567032605035 1.40159562994443 0.161745855819866 -90.5988552006625 458.086513873516 -0.19777673530393 0.843311712708204 APOL2 other 1 1 1 1.40159562994443 -0.19777673530393 0.0844797835986738 -21.3252328159643 31.5250855357998 -0.676452813799583 0.499111063286047 61.616031042129 49.0328285066535 1.25662811872597 0.209559617567476 RAC2 other 1 1 1 -0.676452813799583 1.25662811872597 0.988188163923888 -8.04646888530526 60.7182332969391 -0.13252145934409 0.89463270805092 -1.28605393806244 97.9466783158448 -0.0131301434635215 0.9895299407119 LIF other 1 1 1 -0.13252145934409 -0.0131301434635215 4.24854648355583e-10 41.4755661453457 19.4352014917779 2.13404353759296 0.0333952891220181 -110.36119370307 30.0366944521672 -3.6742123497916 0.00026820246060058 C22orf23 other 3.06999968901744e-06 1 1 2.13404353759296 -3.6742123497916 0.00054319792455623 -6.97290158481715 7.73473303746704 -0.90150513935522 0.367815246927239 29.6766451444594 12.1052469390672 2.45155223134558 0.0146137644635496 APOBEC3F other 1 1 1 -0.90150513935522 2.45155223134558 2.1095575314674e-08 -1.18975158436999 9.4417566996136 -0.126009557566621 0.899782444119755 61.7497166397425 13.8673434624746 4.45288723156233 1.07774976194164e-05 RIBC2 other 0.000141762266114609 0.0911668523626435 1 -0.126009557566621 4.45288723156233 0.0275111725336874 63.5288238130731 24.6807675180163 2.57402140215853 0.0103800540661913 -5.56587465111845 54.4909449054169 -0.102143111314723 0.918689826711185 KRT17 other 1 1 1 2.57402140215853 -0.102143111314723 5.60772714448777e-21 80.4658244804193 72.6747736863025 1.10720433513486 0.268814665293572 -868.983026767496 116.476105262745 -7.46061198395377 4.68780422635774e-13 EMC4 other 4.8389077529785e-17 4.51341790913724e-09 1 1.10720433513486 -7.46061198395377 2.66065619561008e-08 173.555593509822 115.359006585245 1.50448238631088 0.133177933163156 -529.70370460738 90.1136764619713 -5.8781721643653 8.2300156424543e-09 RNF112 other 0.000177545587933061 7.61029546457749e-05 1 1.50448238631088 -5.8781721643653 0.0326701046059983 341.05920865357 173.40696041248 1.96681383401392 0.0498355475258411 -243.722498165223 135.458332985184 -1.79924330083024 0.0726683875646288 SPECC1 other 1 1 1 1.96681383401392 -1.79924330083024 5.55519231206912e-47 229.923068054221 22.1006532908526 10.4034512024758 8.43007451884939e-23 27.2241219361373 31.2606068511592 0.870876309783722 0.384298752976926 MRPS12 essential 5.27132198492239e-43 1 8.26484505827995e-19 10.4034512024758 0.870876309783722 7.29103738520797e-05 15.3470467623571 216.293986571935 0.0709545697760438 0.943466371870031 -1295.19663668232 367.116168471873 -3.52802940299143 0.000463013868740341 HERC2 other 0.36775992570989 1 1 0.0709545697760438 -3.52802940299143 2.36508473034312e-06 -409.198085615557 616.638243595158 -0.663595049229882 0.507301864159078 -4853.86938664133 1062.83611226647 -4.56690295956407 6.45744357022423e-06 SNRPN other 0.0139256188922603 0.0551659404204256 1 -0.663595049229882 -4.56690295956407 8.70228177247797e-21 228.374250645091 38.4995015566853 5.93187551555287 6.11493281154789e-09 -142.576251003687 60.3949830876588 -2.36073004270485 0.0186792877035006 PSMG2 essential 7.49527529063527e-17 1 5.70951276614227e-05 5.93187551555287 -2.36073004270485 0.0060360081315756 246.574797768311 131.722789863067 1.87192207229014 0.0618851063493501 -189.405309902205 217.55663058462 -0.870602331876685 0.384449307594719 TWSG1 other 1 1 1 1.87192207229014 -0.870602331876685 4.08793686358203e-07 330.996762414767 70.7055871192405 4.68133815021665 3.80628240278042e-06 167.978430893873 92.106240475097 1.82374646959225 0.0688717193041827 ARHGAP22 other 0.00254228793546167 1 0.0335752170749261 4.68133815021665 1.82374646959225 0.000263753588886365 94.8875331642353 73.5966473248337 1.28929151820503 0.197978754451313 -247.592684917924 112.343310995348 -2.20389342920627 0.0280525800354085 EIF2AK4 other 1 1 1 1.28929151820503 -2.20389342920627 0.6371998913028 -70.9081053946966 75.8718260873429 -0.93457755073758 0.350523357130476 -84.2735477255982 116.796169158469 -0.72154376579985 0.470961775619011 MYO5C other 1 1 1 -0.93457755073758 -0.72154376579985 0.339071515286684 -163.933551758106 121.917384371021 -1.34462818903022 0.17944603434983 -246.688798235469 187.691497569084 -1.3143312373256 0.189427355718327 CGNL1 other 1 1 1 -1.34462818903022 -1.3143312373256 1.12093507521983e-05 -203.314237111574 624.105791352871 -0.325768867920373 0.744755523213807 -3860.64621104661 970.240972237072 -3.97905914253978 8.10158490292968e-05 TMOD2 other 0.0619765003089046 0.649179998271755 1 -0.325768867920373 -3.97905914253978 0.000116389516590904 -197.609476755977 100.205416125714 -1.97204387144168 0.0492362171898038 -636.315456204791 151.508693570094 -4.19986101926492 3.23989620400909e-05 TTBK2 other 0.572636421627246 0.267064644096469 1 -1.97204387144168 -4.19986101926492 0.611512601348737 -3.66999118982541 13.0161998552907 -0.28195565761336 0.778111601919374 -17.9466419680575 19.6816294804184 -0.911847364361418 0.362354115304096 ELL3 other 1 1 1 -0.28195565761336 -0.911847364361418 4.64509031386498e-06 69.8128816818318 51.1844059891243 1.36394826378694 0.173287553946688 -229.788948968766 78.8592049685278 -2.91391409614735 0.00375292723515308 INO80 essential 0.0266999791240959 1 1 1.36394826378694 -2.91391409614735 4.77484949594984e-10 134.056369262507 50.6422610812584 2.64712448457635 0.00841062138539705 -258.143166580712 79.5458585631933 -3.24521189718049 0.00126361500450512 ICE2 other 3.446008881227e-06 1 1 2.64712448457635 -3.24521189718049 0.631962164638752 -23.5919460237311 25.396593279727 -0.928941364846895 0.353432294263932 -15.3581147231581 39.5321184949094 -0.388497133669569 0.697837374569713 DLL4 other 1 1 1 -0.928941364846895 -0.388497133669569 0.165336788800984 -5.47244977517669 22.7011456876171 -0.241064915862893 0.809618125005008 -56.4367290049026 34.9458684277574 -1.61497571942081 0.107039340751942 ALDH1A2 other 1 1 1 -0.241064915862893 -1.61497571942081 0.000111961820659276 -32.4468283168581 88.2303609558093 -0.367751281592391 0.713237154054258 -492.271798395321 137.163782776358 -3.58893425386174 0.000369717563573452 MINDY2 other 0.551859814029573 1 1 -0.367751281592391 -3.58893425386174 7.93510170207774e-22 38.8595462038218 133.316271196322 0.291483896565011 0.770819565619109 -1640.57793561526 205.592758550508 -7.97974572247503 1.30217963543591e-14 IVD other 6.89242933842472e-18 1.26233293859157e-10 1 0.291483896565011 -7.97974572247503 0.00424214526701122 100.463056336665 37.4938962518066 2.67945096081669 0.00765274453435774 7.25780568215047 57.8209508115023 0.125522074270468 0.900167975079836 KNSTRN other 1 1 1 2.67945096081669 0.125522074270468 3.26048149235785e-09 117.060711139222 86.1993662433951 1.35802287465416 0.175160375293705 -513.090485011409 130.340960242693 -3.93652527997372 9.62354744486597e-05 DUT essential 2.27288164832266e-05 0.767092966830267 1 1.35802287465416 -3.93652527997372 0.252135151130769 14.113921064427 17.0136777465925 0.829563206418067 0.407238699643373 -16.4104012833519 26.4833443330131 -0.619649885490305 0.535811254733192 CHAC1 other 1 1 1 0.829563206418067 -0.619649885490305 0.00112876412110111 6.43756978604082 40.9852308742473 0.157070477553069 0.875261846940274 -209.77428554184 71.1067801731689 -2.95013056463771 0.00334708195964495 CLN6 other 1 1 1 0.157070477553069 -2.95013056463771 4.02056362179046e-09 -297.009131786105 433.936423867201 -0.684453102920441 0.494052748669667 -3564.14018092687 667.9964695679 -5.33556739189411 1.53401874484737e-07 ARPP19 other 2.79187937897129e-05 0.00138475872097372 1 -0.684453102920441 -5.33556739189411 0.000214020157444526 103.964011028452 168.99860311007 0.615176747708022 0.538758213447024 -777.499500610027 268.441637382283 -2.89634465126885 0.00396489188717714 VPS13C other 1 1 1 0.615176747708022 -2.89634465126885 1.36193383523885e-08 38.3579005341447 23.4142443932142 1.63822927146269 0.102093638961168 -159.049385882852 40.6222313129695 -3.9153286449844 0.00010470779855091 CALML4 other 9.24889267510703e-05 0.831379920494222 1 1.63822927146269 -3.9153286449844 0.675677336334607 -4.85894822820203 110.382118338033 -0.0440193420941789 0.964909138692863 -143.694137621998 191.515136926086 -0.750301725118761 0.453477703092934 ISLR other 1 1 1 -0.0440193420941789 -0.750301725118761 1.81586401104924e-06 14.7656622506565 12.9274031856251 1.14219863329361 0.253996894946158 -78.9504632284154 22.4282258980211 -3.52013857838757 0.000476614605602359 THAP10 other 0.0107826004976104 1 1 1.14219863329361 -3.52013857838757 0.577766261463189 8.53702809548303 30.8701321879863 0.276546535126447 0.782259070147939 -35.8857772278716 53.5577244920941 -0.670039243978128 0.503186674265058 LOXL1 other 1 1 1 0.276546535126447 -0.670039243978128 0.344657391231749 -6.29837570621451 5.89184262278001 -1.06899931132965 0.285660104344894 -16.7435798664611 12.421884487398 -1.34790980253016 0.178385700427673 ACKR4 other 1 1 1 -1.06899931132965 -1.34790980253016 0.00135566737115442 127.910524763362 71.8939081694886 1.77915664929239 0.0759106563850339 -331.263663422087 151.578543210925 -2.18542582878057 0.0293890731827729 ANAPC13 essential 1 1 1 1.77915664929239 -2.18542582878057 0.00366208280181745 37.8169722873297 29.1910165668227 1.29550035370508 0.195833149474058 -134.042671997794 59.6417051171799 -2.24746545616756 0.0251095388681638 MBD4 other 1 1 1 1.29550035370508 -2.24746545616756 1.13590387208739e-05 313.843371124872 115.752413538244 2.71133328050373 0.00696484796384331 -146.809594705438 141.736234811097 -1.03579437467845 0.300869596929201 COPB1 essential 0.0627700479715492 1 1 2.71133328050373 -1.03579437467845 2.0376122793561e-16 379.206649287806 68.8727695588112 5.50590097823781 6.26830829422222e-08 -105.07335453255 84.3331619608348 -1.24593163696799 0.213455512701743 PSMA1 essential 1.67308344257929e-12 1 0.000575806799907253 5.50590097823781 -1.24593163696799 9.06578749851249e-07 592.830661619128 251.702848904675 2.35527990326261 0.0189499072345397 -555.227369009035 337.879829536733 -1.64326876147152 0.101046592931501 PALLD other 0.00550927906284604 1 1 2.35527990326261 -1.64326876147152 5.55042387895253e-11 644.910065473896 131.687233537623 4.89728615408757 1.37139963371212e-06 13.4187223851958 178.398610346683 0.0752176396392277 0.940076048950718 SPCS3 essential 4.11230905191593e-07 1 0.0122479701286829 4.89728615408757 0.0752176396392277 3.81563438915252e-06 -302.387553020554 156.389286721191 -1.9335566991852 0.0538161248865548 -938.280518255088 195.409196524653 -4.80161903811273 2.16853323015682e-06 BBOX1 other 0.0220925231131931 0.0188944300343564 1 -1.9335566991852 -4.80161903811273 0.0174061718087477 -13.935610693318 10.230590583401 -1.3621511465749 0.173851875155154 -35.4410318910365 12.736596732988 -2.78261396148655 0.00562592110732686 MYOD1 other 1 1 1 -1.3621511465749 -2.78261396148655 1.8720970365318e-05 45.2882969813888 43.9075174533241 1.03144745155616 0.302901541541365 -150.405345373779 54.6627625053213 -2.75151379989509 0.00617872937787462 SERGEF other 0.101149402883813 1 1 1.03144745155616 -2.75151379989509 0.0513268450170897 32.7418805194542 104.453025544368 0.313460336345611 0.754080510027878 -208.038867267408 130.039028837459 -1.59981867849416 0.110361491870505 KCNC1 other 1 1 1 0.313460336345611 -1.59981867849416 0.171644084394978 -4.55954535621314 6.23107086580013 -0.731743460219442 0.464717381647835 6.24473783978774 7.75738567440398 0.80500546213561 0.421254286162986 TPH1 other 1 1 1 -0.731743460219442 0.80500546213561 0.499025304200397 9.49490875207789 8.05591459548008 1.17862579593448 0.239188572861822 8.33049460235411 10.1005576310793 0.824755910180767 0.409960136282923 E2F8 other 1 1 1 1.17862579593448 0.824755910180767 0.000136353730141361 323.193591092705 118.848468879339 2.7193753031924 0.00680052156595488 -53.8283648460589 156.986052829892 -0.342886287512347 0.731848507601053 DCTD other 0.664315373248709 1 1 2.7193753031924 -0.342886287512347 0.0852857809494595 8.18420903844228 24.9716841046731 0.327739571113296 0.743265178496535 41.2450918643265 18.8195650235377 2.1916070755483 0.0289337379357778 SOX15 other 1 1 1 0.327739571113296 2.1916070755483 0.00170879762545383 209.10764691224 58.575618148264 3.56987520614731 0.000396666372532876 -24.4927280141361 43.7853554689024 -0.559381732815473 0.576187141751952 PIMREG other 1 1 1 3.56987520614731 -0.559381732815473 0.0228701530063383 197.788548850775 71.8043880055745 2.75454682289639 0.00612216918741052 0.840942151673136 52.3284220709785 0.0160704664576447 0.987185492382782 RPAIN essential 1 1 1 2.75454682289639 0.0160704664576447 0.882016371972296 -15.7510935966718 35.2771622087459 -0.446495483493477 0.655460040196253 6.53902136055178 25.7087106345411 0.254350420505579 0.799344217418877 USP6 other 1 1 1 -0.446495483493477 0.254350420505579 0.339203758898768 3.03764640388989 2.49607233374941 1.21697050314522 0.224270753977797 -1.61779189544285 1.88113045926525 -0.860010472678618 0.390253744213055 SHBG other 1 1 1 1.21697050314522 -0.860010472678618 0.630026182864192 83.291230149407 86.6685733192249 0.96103151303324 0.337066547577204 -1.3503076928391 63.160898810054 -0.0213788549289003 0.982953176690023 PLD2 other 1 1 1 0.96103151303324 -0.0213788549289003 0.001021932282989 74.5057213313649 352.692233095494 0.211248545729081 0.832791583441306 990.833082069999 265.801633010215 3.72771630801802 0.000218555539684084 CD68 other 1 1 1 0.211248545729081 3.72771630801802 0.0124241543283703 86.7053090027645 41.4091064908863 2.09387056013506 0.0368458375265771 63.1706537991029 30.9533642950864 2.04083320949803 0.0418664164481138 TXNDC17 other 1 1 1 2.09387056013506 2.04083320949803 6.16417497156021e-06 -2651.22151620715 1717.91366242632 -1.5432798365796 0.123485051943913 -6057.23551776259 1294.68191810122 -4.67855110438721 3.85587282266386e-06 ATP1B2 other 0.0350001854885188 0.0332684707139437 1 -1.5432798365796 -4.67855110438721 8.93305898832921e-05 148.154225869725 83.0885208500618 1.78308897972895 0.0752642236870772 -252.270539640893 62.6185168085912 -4.0286891561488 6.61213055034418e-05 FXR2 other 0.445044998798561 0.533069964968748 1 1.78308897972895 -4.0286891561488 0.432211390699491 -248.68441184194 405.43133853513 -0.61338231213321 0.53994196910857 347.886205478696 295.463589245005 1.17742496247218 0.239665320623641 KIF1C other 1 1 1 -0.61338231213321 1.17742496247218 1.81227080679713e-06 343.291298618268 94.2924418000754 3.64070854529502 0.00030437189460751 -272.544668136686 71.0621971768648 -3.83529751350577 0.000143819616596839 MPDU1 other 0.0107667008631817 1 1 3.64070854529502 -3.83529751350577 6.83905861381481e-10 65.7366680400727 43.8160675623801 1.50028680566745 0.1342605907767 -284.186740074829 66.9016422071907 -4.24782906217337 2.63821387255294e-05 CCNT1 other 4.90223721438246e-06 0.218734312173364 1 1.50028680566745 -4.24782906217337 1.72649868433523e-07 34.5759585991706 44.8549718449061 0.770838932163932 0.441225740825736 -267.536117911187 68.5470096367256 -3.90295826658277 0.00011027389144297 PUS7L other 0.00109822581310564 0.872928124662554 1 0.770838932163932 -3.90295826658277 9.05196317679861e-24 8.73685933831674 2.7956700250159 3.12513968391783 0.00189536833506989 -7.05308165497447 3.45761789938061 -2.03986729020518 0.0419629898741369 KLK14 other 7.9602964176767e-20 1 1 3.12513968391783 -2.03986729020518 4.66803256220207e-09 -16.9510762164187 21.905266012607 -0.773835670685898 0.439445439198371 -96.7174598087914 27.0919096954057 -3.56997571954821 0.000396518536389735 SIGLEC9 other 3.23354615583738e-05 1 1 -0.773835670685898 -3.56997571954821 2.19200220427811e-26 190.178405955541 42.8059469656531 4.44280338215943 1.12663184235013e-05 -334.04280285283 63.4242574877244 -5.26679879409677 2.1831549263235e-07 NGDN other 1.95373156467308e-22 0.00196505774918378 0.0976677144133327 4.44280338215943 -5.26679879409677 0.0226504373509155 -3.02978356778915 7.67045746877406 -0.394993855336947 0.693039705932049 20.5852780542394 11.3764176072861 1.80946926922368 0.0710635145771912 RIPK3 other 1 1 1 -0.394993855336947 1.80946926922368 0.884930202686585 -8.75877538287835 17.9157036373277 -0.488888159805752 0.625165580916528 -7.00836646744918 26.5716258953704 -0.263753768589308 0.792093704536046 ADCY4 other 1 1 1 -0.488888159805752 -0.263753768589308 1.52984695175578e-20 132.834841820848 39.3815436549554 3.37302272822749 0.000809536556952773 -291.525554280451 58.3449650162158 -4.99658461016178 8.44888383160136e-07 RAB2B other 1.31367957747269e-16 0.00747219286066825 1 3.37302272822749 -4.99658461016178 5.36516666853488e-08 -35.0156437125852 171.697408136535 -0.203938103041954 0.838496805590559 -1185.93610992302 256.053343844584 -4.63159782300226 4.7938123634714e-06 BCL2L2 other 0.000351042855122237 0.0412028172640367 1 -0.203938103041954 -4.63159782300226 0.362841659963084 46.4295293304109 41.6336823502854 1.11519151584469 0.265379855141649 2.64583433326418 62.0828877056539 0.0426177716766101 0.966025649357653 AJUBA other 1 1 1 1.11519151584469 0.0426177716766101 2.03055112372494e-06 43.0646909398816 37.4020529439524 1.1513991225138 0.250197637896807 -143.886890924487 50.9374086178645 -2.8247783864298 0.00494793707034385 DTD2 other 0.0120188321013279 1 1 1.1513991225138 -2.8247783864298 8.68068805627007e-15 113.221581409331 61.1107967789604 1.85272631641274 0.0645940594500845 -387.17229100002 84.72961609039 -4.56950366194251 6.36643052256579e-06 PARP2 other 6.95409920187795e-11 0.0544138816763698 1 1.85272631641274 -4.56950366194251 1.03500982078773e-05 289.269263336157 213.703266041361 1.35360244461669 0.176562930959674 -696.407358940807 291.039922370922 -2.39282416401024 0.0171405466132716 HEATR5A other 0.0574223448573031 1 1 1.35360244461669 -2.39282416401024 6.02392893362261e-10 141.139696815418 93.5485780560318 1.50873161033919 0.132091662394637 -437.241679493101 124.581106918936 -3.50969493133185 0.000495301056255238 SNX6 other 4.32939772459457e-06 1 1 1.50873161033919 -3.50969493133185 1.69687249723743e-18 118.845242369837 46.9516341778327 2.53122696261651 0.0117161156100162 -311.800496356533 64.312179632623 -4.8482340069589 1.7343148908799e-06 EAPP other 1.42910601717336e-14 0.0151735209803082 1 2.53122696261651 -4.8482340069589 0.0437353488731703 -205.07648114901 130.42596470922 -1.5723593197583 0.116590945096755 -446.842718344068 178.651461616169 -2.50119822307474 0.0127422982829627 EGLN3 other 1 1 1 -1.5723593197583 -2.50119822307474 0.534289832507777 11.1424166963125 42.0711760499203 0.264846808253975 0.791253503644947 52.9159675283611 55.9138345856143 0.946384162712667 0.344480503373863 MIS18BP1 essential 1 1 1 0.264846808253975 0.946384162712667 1.02644613177066e-14 0.0218066222017193 4.83380314451991 0.0045112764317764 0.996402588324092 -45.1245050514056 7.16924165570795 -6.29418106104412 7.51050634615996e-10 NRL other 8.21054260803353e-11 7.04560600333266e-06 1 0.0045112764317764 -6.29418106104412 0.892066804303462 -7.42908211640607 402.344571661959 -0.0184644770668059 0.985276743159155 -201.003261791679 559.262011886724 -0.359408036876267 0.71946346717747 RNASE1 other 1 1 1 -0.0184644770668059 -0.359408036876267 4.96658913977254e-16 356.93024257639 103.446027497074 3.45040066991927 0.000614025759894788 -585.270202732928 153.425687243867 -3.81468196914545 0.000155947245455232 NEDD8 other 4.0605777740819e-12 1 1 3.45040066991927 -3.81468196914545 6.9098155228982e-12 376.339005828929 142.167268324096 2.64715648169448 0.00840983836549485 -752.991957890916 211.995529977999 -3.55192375032181 0.000423914340876816 DAD1 essential 5.22243857220646e-08 1 1 2.64715648169448 -3.55192375032181 0.41450125365398 76.7919896640837 65.9337492010918 1.16468410479549 0.244782285924439 31.664771748494 91.1386603491306 0.347435123878207 0.72843171935181 TEP1 other 1 1 1 1.16468410479549 0.347435123878207 0.2822447644653 1.69692450526721 2.08570701493993 0.813596777069903 0.416322116239252 -0.647696120358735 2.41767719963763 -0.267900164858987 0.788903443220231 CHRNA10 other 1 1 1 0.813596777069903 -0.267900164858987 0.0173420754880531 -79.911504895062 91.5446692294667 -0.872923629171187 0.383184096952841 -246.146365860224 104.620845586694 -2.35274685919313 0.0190778067190516 CDKN1C other 1 1 1 -0.872923629171187 -2.35274685919313 0.0100739288963818 43.1560205792241 15.4702851846392 2.78960730614551 0.00550741988794694 73.7203306549516 31.8745835983289 2.31282490099154 0.0211948510422827 SGO1 other 1 1 1 2.78960730614551 2.31282490099154 0.252229653326782 26.3372724920213 17.1417442794565 1.53644063653342 0.125154035368007 1.69203829897378 36.4242392932511 0.0464536344973795 0.96296990924235 CDH15 other 1 1 1 1.53644063653342 0.0464536344973795 0.0197103742974538 103.267356907277 36.8799084061263 2.80009797665665 0.00533466251373632 121.473510624974 101.977712844028 1.19117704483885 0.23422918309065 DOHH essential 1 1 1 2.80009797665665 1.19117704483885 0.0158251267349227 208.84026880331 176.136668960579 1.18567172886669 0.236403717151609 -1178.87079804783 507.581464554579 -2.32252530947388 0.0206684993603406 SHC2 other 1 1 1 1.18567172886669 -2.32252530947388 0.132832808431733 -62.3334255551513 34.6711850450771 -1.79784525605657 0.0728964407949675 -129.478980706224 101.825278786288 -1.27157992837885 0.204203414431794 PLPPR3 other 1 1 1 -1.79784525605657 -1.27157992837885 0.411572604571203 -32.8100759780675 151.101676612444 -0.217139059695685 0.828201314134953 108.141077230272 174.429269398582 0.619970934941901 0.535600057113425 INS-IGF2 other 1 1 1 -0.217139059695685 0.619970934941901 0.172942580313905 -135.065756285628 160.487135667907 -0.841598647290442 0.400476130040343 2.93018611349745 198.590822483569 0.014754891876939 0.988234507015563 SYT5 other 1 1 1 -0.841598647290442 0.014754891876939 0.258053264883254 -18.9897783145007 14.8847607103313 -1.27578660376583 0.202708670420599 -46.597423732713 31.6284082353071 -1.47327754802076 0.141396121415815 CBFA2T3 other 1 1 1 -1.27578660376583 -1.47327754802076 1.13266604211856e-12 34.9040994960373 40.1521501028767 0.869295900882194 0.385164689976584 -209.984092717572 51.8558340956289 -4.04938222245802 6.0800201153605e-05 ERMARD other 8.7135998620181e-09 0.491569626326896 1 0.869295900882194 -4.04938222245802 1.26012052777547e-14 -169.172909728562 141.676988455178 -1.19407471582503 0.233099470617989 -1105.97216409772 182.973474388702 -6.0444398719141 3.22706490140483e-09 PHF10 other 1.00671028963982e-10 3.00213847777692e-05 1 -1.19407471582503 -6.0444398719141 0.000441845424527194 298.76663422941 186.150796320765 1.60497102421518 0.109224224740998 -434.961710524539 285.163654887939 -1.52530556776412 0.127907928914199 SH3BP4 other 1 1 1 1.60497102421518 -1.52530556776412 3.5831715118364e-27 405.22718519633 58.9243171230821 6.87707902239892 2.21121220167523e-11 -258.694057469537 83.3315684290368 -3.1043944371434 0.00203509879767346 CDC16 essential 3.20729682024476e-23 1 2.11237101626035e-07 6.87707902239892 -3.1043944371434 2.53338862223958e-15 196.018177838899 25.0774545068321 7.81651015598475 4.09476014467167e-14 -72.0848402628814 79.7193565698545 -0.904232589982292 0.366370286815041 THEM6 other 2.04748468449403e-11 1 3.96168043996984e-10 7.81651015598475 -0.904232589982292 6.36526168248635e-17 463.150433234065 85.1078474552416 5.4419239480547 8.79932330759551e-08 126.88992163377 106.083490942009 1.19613259807914 0.232293404971512 NECTIN2 other 5.26725404225746e-13 1 0.000805930021742673 5.4419239480547 1.19613259807914 3.48534558257876e-14 -19779.5499663287 9082.35375623873 -2.17779999515456 0.0299550330547512 -65290.3931839831 11320.786757517 -5.76730174169479 1.52572212793955e-08 APOE other 2.76736439256754e-10 0.000140580036868351 1 -2.17779999515456 -5.76730174169479 3.96493403498251e-45 375.612004848628 48.8402542273123 7.69062345786438 9.79144643816337e-14 -18.0454184936323 60.8774022824781 -0.296422281783632 0.767048433547824 TOMM40 essential 3.74805214326897e-41 1 9.46245383784108e-10 7.69062345786438 -0.296422281783632 0.0015769155014499 -500.313203537692 486.507032057299 -1.02837815400532 0.30434083966818 -1578.73723169166 606.411345976249 -2.60340978473958 0.00954425523234952 APOC1 other 1 1 1 -1.02837815400532 -2.60340978473958 0.00950278007141247 585.017127583337 282.919403167541 2.06778722503136 0.0392480143943673 -747.789287420848 585.24385399035 -1.27773966752871 0.202019572101036 GADD45G other 1 1 1 2.06778722503136 -1.27773966752871 1.98831310977649e-13 108.082321467817 18.4365669601095 5.86238868123716 8.98933857198859e-09 44.5762608847223 25.6293520615144 1.73926600944621 0.082690521241676 FAM98C other 1.55505968315619e-09 1 8.37446781366457e-05 5.86238868123716 1.73926600944621 1.91194457311356e-06 -2298.09796170474 1605.11290867006 -1.43173601638333 0.152932563805802 -10583.8531613229 2349.97647829566 -4.50381238241114 8.57083336303329e-06 KIF1A other 0.0113359193739903 0.0728263710856938 1 -1.43173601638333 -4.50381238241114 1.61407475134978e-09 -26.4458766141035 93.6513138834992 -0.282386605349731 0.777780474322245 -532.247805283635 123.018105996009 -4.32658104247601 1.87769128557058e-05 TULP4 other 1.13921395950267e-05 0.156693337780865 1 -0.282386605349731 -4.32658104247601 0.0173017252103979 -184.086955254788 85.9631468675972 -2.14146366161216 0.03278779274917 -322.858042307175 112.919115328843 -2.85919741194348 0.004449963919375 SNX9 other 1 1 1 -2.14146366161216 -2.85919741194348 1.73923402296462e-06 18.651234478984 9.98089874906183 1.86869288507081 0.0623343543241189 -23.7363948028 13.2867246120913 -1.78647450713317 0.0747155845727826 RTN4IP1 other 0.0103467032026165 1 1 1.86869288507081 -1.78647450713317 8.39922462128624e-22 26.0752261463277 40.6917578676557 0.640798714843772 0.521990121383384 -342.986621841753 54.173838622963 -6.33122242322274 6.05440910423681e-10 QRSL1 essential 7.29220681620072e-18 5.68751191252006e-06 1 0.640798714843772 -6.33122242322274 9.33097689228405e-15 29.1624556660776 22.2491561640329 1.31072187417249 0.190641722864327 -130.542213981216 29.6207944480443 -4.407113867597 1.32042409357252e-05 C6orf203 other 7.47131319765184e-11 0.111087278992256 1 1.31072187417249 -4.407113867597 0.000152323194530083 -39.0202716222534 38.0413069309203 -1.02573425495372 0.305583006583542 -169.370404402836 49.9701428009458 -3.38943206701483 0.000763774573949832 RSPH3 other 0.738462847081842 1 1 -1.02573425495372 -3.38943206701483 0.516954986452364 -10.5212419792562 15.5441673380933 -0.67686108560298 0.498851399915631 -22.6958013361591 20.4184431154486 -1.11153437154018 0.266948158569477 MAS1 other 1 1 1 -0.67686108560298 -1.11153437154018 1.2357506437943e-05 55.4818978855281 209.071333642604 0.265373051957335 0.790847231060128 -734.370603403797 268.039922125653 -2.73978069229379 0.00639972526837283 AFDN other 0.0680527879537521 1 1 0.265373051957335 -2.73978069229379 1.20051268548983e-28 2028.20146192383 356.932109468951 5.68231719175229 2.42722691235667e-08 -727.341776993603 491.923744564599 -1.47856610913826 0.139975082069078 ACTN4 other 1.08070151947795e-24 1 0.000224348583509127 5.68231719175229 -1.47856610913826 0.00012156650013893 21.6394643301868 46.5110392485956 0.465254371430546 0.641980534920506 -146.273068053548 56.3196264358488 -2.59719528182882 0.00971521984822995 STK33 other 0.596370350016146 1 1 0.465254371430546 -2.59719528182882 3.11473422981118e-23 305.791399704288 101.160326570856 3.02283919071872 0.0026511299879006 -754.036012699577 148.83099891047 -5.06639086090642 5.9882818299292e-07 NDUFA10 other 2.73037602585248e-19 0.0053199895777091 1 3.02283919071872 -5.06639086090642 0.000174772825366517 22.8406555771259 8.98801506388255 2.54123467915723 0.0113924345732947 8.10397775466978 11.1601447632329 0.726153461859058 0.468135221235202 CACNG6 other 0.83960865306075 1 1 2.54123467915723 0.726153461859058 1.2324620745472e-06 122.978728211386 33.8579046525123 3.6322013861617 0.000314438801071543 -23.552866927998 49.7279486936281 -0.473634395681717 0.635997710723416 SCO2 other 0.00740956199217778 1 1 3.6322013861617 -0.473634395681717 0.89385345324185 -0.320594823551586 8.24665130241001 -0.0388757583890925 0.969007156792942 -2.53897348196073 10.0579940170838 -0.252433385588438 0.800824514414267 HRC other 1 1 1 -0.0388757583890925 -0.252433385588438 5.32043067575955e-08 107.376312435426 25.233781123204 4.25526051411643 2.55546614659827e-05 58.1185708693055 30.7762763646157 1.8884211390864 0.0596299946763947 TRPM4 other 0.000348435004955493 1 0.218287918242424 4.25526051411643 1.8884211390864 0.156906030595707 -162.957128816891 270.029863189297 -0.603478174199774 0.546504447423234 -702.188813953751 396.599592332669 -1.77052328728758 0.0773387071755082 SULT4A1 other 1 1 1 -0.603478174199774 -1.77052328728758 0.316920507865036 -174.955049041783 743.094570960111 -0.235441161702652 0.813976381845895 -2242.35005438392 1533.22834576369 -1.46250234714192 0.14432074668177 OLFM1 other 1 1 1 -0.235441161702652 -1.46250234714192 0.000148349908568424 261.31123966465 109.578600614126 2.38469225013049 0.0175180262891584 -498.670558566187 226.09372092925 -2.20559224960623 0.0279312370061689 CAMSAP1 other 0.719942106282563 1 1 2.38469225013049 -2.20559224960623 1.80353129698052e-10 260.776679404377 57.3078903633636 4.55044982027623 6.94239653303049e-06 -331.743230886216 118.243471793233 -2.80559447261764 0.00524612195801512 UBAC1 other 1.31675819992548e-06 1 0.0606696033021535 4.55044982027623 -2.80559447261764 0.498349584262322 -44.423867322482 102.195496167681 -0.434694961993156 0.66399793778706 172.841540653184 210.860148434707 0.819697519594155 0.412834380578596 COL5A1 other 1 1 1 -0.434694961993156 0.819697519594155 3.18530218568628e-27 716.165614375905 156.845304418409 4.56606346636572 6.47069129638138e-06 -1167.16895766799 229.271430600015 -5.09077365031241 5.30959959466737e-07 ATXN10 other 2.85243810728206e-23 0.00472554363925396 0.0565926660781516 4.56606346636572 -5.09077365031241 4.52340736008076e-42 255.911898470451 130.614231189003 1.95929567659545 0.0507253922454193 -859.78914070837 148.170717355346 -5.80269270510722 1.26938443919909e-08 TUBGCP2 essential 4.24612248890781e-38 0.000117049939138548 1 1.95929567659545 -5.80269270510722 0.0383030629713342 -84.9919923099086 153.75062631379 -0.552791194075844 0.580694315449962 -297.702991344413 174.416986475101 -1.70684631904767 0.0885742416900887 CALY other 1 1 1 -0.552791194075844 -1.70684631904767 3.90189842733645e-11 -25.139820050613 53.464403006628 -0.470216043513969 0.638440742191455 -235.843325314759 60.6683737711752 -3.8874179519678 0.000117435888216809 CYP2E1 other 2.90262224009558e-07 0.928095824577439 1 -0.470216043513969 -3.8874179519678 0.0881028001639023 49.584816404785 31.4991813957383 1.57416206414474 0.116185425672752 -52.7476034676782 66.3844538909703 -0.794577651483143 0.42729753917716 PNPLA7 other 1 1 1 1.57416206414474 -0.794577651483143 4.39965026263998e-72 290.73035746046 34.2494797431956 8.48860653184724 3.27007698756187e-16 -246.496936378325 48.454311800706 -5.08720333067931 5.4000748853055e-07 PAK4 other 4.30065813173058e-68 0.00480336661047924 3.17753380881387e-12 8.48860653184724 -5.08720333067931 8.33372754867219e-08 76.2924117287539 27.2034098732625 2.80451649569636 0.0052633808690685 -12.1476045698877 34.9275227302192 -0.347794622129831 0.728161505578835 CEP85 essential 0.000540525568806878 1 1 2.80451649569636 -0.347794622129831 0.737150493313793 9.07436628047588 48.8174302741835 0.185883735164052 0.852622187930394 -66.8547189591688 105.928111191428 -0.631132927862293 0.528283569762986 ASS1 other 1 1 1 0.185883735164052 -0.631132927862293 2.13765758589565e-06 125.883363350449 30.6667411025071 4.10488231956793 4.82801472171586e-05 -91.3134915728077 66.5432396408428 -1.37224295158545 0.170691757913359 EXOSC2 essential 0.0126335563326433 1 0.407339602071167 4.10488231956793 -1.37224295158545 1.18349661126042e-13 609.22186732187 86.8933179264901 7.0111474835989 9.02270659927009e-12 -130.615601965601 183.104821577703 -0.713337862106335 0.476017475599456 POMT1 other 9.31056784078572e-10 1 8.64736200474045e-08 7.0111474835989 -0.713337862106335 1.19610139910298e-11 341.758886158883 65.6894428486567 5.20264552930171 3.02693285883743e-07 -363.409991809997 138.423229764543 -2.62535408564122 0.0089594914413426 UCK1 other 9.00544743384635e-08 1 0.00274724426268085 5.20264552930171 -2.62535408564122 0.895470962789307 9.54435364640769 35.0305951258394 0.272457650580065 0.785398839892535 -19.0457568344938 76.0122922233004 -0.250561537843686 0.802270880436398 FIBCD1 other 1 1 1 0.272457650580065 -0.250561537843686 2.20783288227228e-07 2368.62645372644 501.562033173397 4.72249950567446 3.14369046252151e-06 -991.350194512704 1056.91011444699 -0.937970202916844 0.348777825508045 PRRC2B other 0.00139579194817254 1 0.0278090858314653 4.72249950567446 -0.937970202916844 6.51647308278858e-35 996.192363583522 166.313924227511 5.98983138790453 4.40547515565276e-09 -92.8974781707121 206.556597106544 -0.449743457589954 0.653119452277302 CHMP2A essential 5.99841347270689e-31 1 4.12352474569098e-05 5.98983138790453 -0.449743457589954 9.2166691568345e-33 277.34291215578 83.7745547167741 3.31058652705972 0.0010085626829802 -314.493885146397 104.045328897064 -3.02266222309256 0.00265367816007292 UBE2M essential 8.43233061158788e-29 1 1 3.31058652705972 -3.02266222309256 8.94280161843508e-46 1874.35881377215 355.493289802011 5.2725575068268 2.12182928735415e-07 -1094.59259201843 441.456821495521 -2.47950091315903 0.0135335434139332 TRIM28 other 8.46704457233433e-42 1 0.00193086465149228 5.2725575068268 -2.47950091315903 3.79388058349662e-05 50.0333454795058 18.0532164433963 2.77143663769719 0.00581922428136712 17.4788529494016 21.9155552081208 0.79755464935357 0.425562121481526 TMEM160 other 0.198230260487698 1 1 2.77143663769719 0.79755464935357 4.13046676063222e-18 58.6718451326788 76.6145629168415 0.765805388674761 0.444205531464028 -335.452827253584 93.0056252643149 -3.60680148432154 0.000345782768513133 ZC3H4 other 3.46009200538161e-14 1 1 0.765805388674761 -3.60680148432154 0.549099650240889 8.50575208008216 13.7857808279403 0.61699458204378 0.537559618669133 16.1282181807614 16.7351364655184 0.963733890906265 0.335712342281758 NPAS1 other 1 1 1 0.61699458204378 0.963733890906265 8.86961027052916e-15 19.571200860461 26.8043438558119 0.730150343009328 0.465688624102151 -162.338695198092 37.9213361645553 -4.28093288943305 2.28825603050538e-05 GMFG other 7.10455782669386e-11 0.190062545893777 1 0.730150343009328 -4.28093288943305 0.908265696678765 33.8664278100473 88.7563993283789 0.381566039928558 0.702969160159736 53.400437694144 122.14719994675 0.437181021893452 0.662196525128601 MAP3K10 other 1 1 1 0.381566039928558 0.437181021893452 0.434666256694369 3.46142016687436 6.93684353935902 0.498990664447681 0.618036477403335 -1.82881973470449 8.86334006630354 -0.20633527778735 0.836624900448909 ARHGEF16 other 1 1 1 0.498990664447681 -0.20633527778735 1.02116019079651e-42 261.828697293621 69.9556195161314 3.74278291157503 0.000206237443284321 -430.263909322168 89.3856319159566 -4.81356902781329 2.04454406044831e-06 LRRC47 other 9.60094811386879e-39 0.017840691471472 1 3.74278291157503 -4.81356902781329 0.00617962845323315 91.8697588399626 65.9680935790284 1.39263928750502 0.164437030888325 -31.2790746641573 84.7406699346132 -0.369115262934463 0.712220588590032 SESN2 other 1 1 1 1.39263928750502 -0.369115262934463 3.16343185305932e-16 262.258773284294 88.2299638584769 2.97244566148711 0.00311763392949082 -217.811893766057 113.337612776655 -1.92179708421494 0.0552812642739225 ATPIF1 other 2.59274874676742e-12 1 1 2.97244566148711 -1.92179708421494 1.44437714475143e-35 45.017599208299 11.4986613059529 3.91502958566083 0.000104833240069579 -56.6996588947063 14.7708416228573 -3.83862073282037 0.000141993779344138 MED18 essential 1.3330156668911e-31 1 0.869801392857296 3.91502958566083 -3.83862073282037 8.09165246666036e-13 -14.0654100984 82.0734545950185 -0.171375875035407 0.864007548963969 -449.722244837797 105.429142315565 -4.26563505080702 2.44519136610622e-05 THEMIS2 other 6.2443282085218e-09 0.202853075732172 1 -0.171375875035407 -4.26563505080702 0.0574999439341715 243.687976878614 133.298403877929 1.82813874577055 0.068208748780646 -175.726924855493 265.703387595871 -0.661365014746331 0.508726004152092 CLIP1 other 1 1 1 1.82813874577055 -0.661365014746331 0.0062302930861853 4.30248554913298 1.97546010117489 2.17796631102501 0.0299413412242688 -4.90957803468203 3.93767986466909 -1.24682000655597 0.213129836594378 CCDC62 other 1 1 1 2.17796631102501 -1.24682000655597 0.0592549901321415 -303.89505865692 1079.96672720484 -0.281392982766662 0.778542804526517 -4987.943840545 2204.11843886441 -2.26301080404502 0.0241272253232984 HIP1R other 1 1 1 -0.281392982766662 -2.26301080404502 1.32148852607036e-31 59.5314905109097 38.2824800061261 1.55505835832431 0.120662743815757 -309.563621616139 52.8411694537396 -5.85837945708508 9.26139259299842e-09 ZNF331 other 1.20242240987142e-27 8.55382219889334e-05 1 1.55505835832431 -5.85837945708508 0.00128637634047112 17.4042972207909 30.7716326371077 0.56559550889097 0.57196241925111 -103.450804361275 45.8778654795066 -2.25491755730191 0.0246384327517733 ZNF236 essential 1 1 1 0.56559550889097 -2.25491755730191 0.00169998867871011 19.3466637733234 49.0222968422909 0.394650292204043 0.693293089005568 -94.2657096657818 63.0063578602547 -1.49613011872324 0.135339934279417 SLC7A10 other 1 1 1 0.394650292204043 -1.49613011872324 1.2481439147992e-25 285.306848777167 138.872976431318 2.05444468829593 0.0405254775147822 -709.751801789431 177.652360898721 -3.99517235908877 7.58259779002694e-05 LRP3 other 1.10847661073317e-21 0.608655124605462 1 2.05444468829593 -3.99517235908877 3.67572707776226e-05 123.352007202193 34.0716980724089 3.62036570469857 0.000328734452817424 -77.8080369930837 68.9105129515065 -1.12911707750367 0.259469300532281 C12orf65 other 0.192350797979299 1 1 3.62036570469857 -1.12911707750367 4.03585840705228e-46 212.823414405256 64.3776986627571 3.305856202163 0.00102476449075012 -461.830898568859 82.2775344943955 -5.61308626232982 3.5323456751855e-08 UBE4B other 3.82478301236344e-42 0.000323668834217247 1 3.305856202163 -5.61308626232982 2.89363541807176e-17 -26.3001810198267 29.4648711188483 -0.892594469995927 0.372564506901802 -208.82437232773 37.6498096844205 -5.54649210920556 5.04986631427025e-08 CASZ1 other 2.40200676054137e-13 0.000461254789145445 1 -0.892594469995927 -5.54649210920556 0.18454762800653 2.92326372025258 2.35629249898647 1.24062005099536 0.215411778338168 -0.63054782894509 3.44435272804575 -0.183067147511007 0.854830235071196 PKDREJ other 1 1 1 1.24062005099536 -0.183067147511007 0.0131667118851341 21.3594678855455 7.33450476533163 2.91218951639466 0.00377288043886195 9.6695606224736 15.9943520030723 0.604560948803442 0.545784516512296 HSD17B3 other 1 1 1 2.91218951639466 0.604560948803442 7.31686967930917e-06 307.925572670344 101.805446697688 3.02464733134301 0.00263600006495214 -552.52153557558 222.007102375807 -2.48875612384818 0.0131903652423567 HABP4 other 0.0411866594248313 1 1 3.02464733134301 -2.48875612384818 2.6784505283365e-08 165.463869587044 27.4648501597795 6.02456844382697 3.60317637196808e-09 137.915796982746 59.8925892370439 2.30271889627114 0.0217636587765534 SLC35D2 other 0.000178679434745328 1 3.37761753108288e-05 6.02456844382697 2.30271889627114 5.1399991591164e-07 29.7880888888892 7.98540401006412 3.73031706991241 0.000216440807427915 -15.1768888888886 12.9851380398626 -1.16878918362652 0.243125752069433 POLN other 0.00317857547999758 1 1 3.73031706991241 -1.16878918362652 4.74780747724974e-20 9.99848092136442 41.2644665077842 0.242302440029808 0.808659495548841 -305.806991367845 52.5551750568077 -5.81877980688474 1.14766787406703e-08 PPIL4 essential 4.0570014893099e-16 0.000105929744776386 1 0.242302440029808 -5.81877980688474 0.000448282970718664 12.9229011246593 5.00184900868302 2.58362479599557 0.0101005085091652 1.51993959746693 6.37044587040687 0.238592341633045 0.811533547073035 ULBP2 other 1 1 1 2.58362479599557 0.238592341633045 0.0997020718105031 -130.140972618374 523.632724240386 -0.248534834806524 0.803837108861863 -1070.20010141345 690.286705322058 -1.55037043762004 0.121774854660806 AKAP12 other 1 1 1 -0.248534834806524 -1.55037043762004 2.01185595124927e-06 56.0961209355412 437.325305071522 0.128270923920963 0.897993448289884 -1846.28192939088 576.510653396826 -3.20251138207508 0.00146168474879234 SYNE1 other 0.0119142109432982 1 1 0.128270923920963 -3.20251138207508 1.17993958175401e-12 52.8616331222271 77.977981788845 0.677904607295044 0.498190945406735 -404.521979309875 99.3141758591797 -4.07315446974516 5.50763174137147e-05 LATS1 other 9.07491532327012e-09 0.446503705272985 1 0.677904607295044 -4.07315446974516 0.000744348173086611 6.93158330414467 2.68050743538887 2.58592205812669 0.010035960556497 3.37552100313787 3.31470955681563 1.01834593507513 0.309079619975334 EPS8L1 other 1 1 1 2.58592205812669 1.01834593507513 2.9139015639538e-07 -15.3850456437293 15.0906330333526 -1.01950962625133 0.308523874596938 -64.5058506884518 18.7249054082522 -3.44492264617922 0.000626266744393239 LILRB2 other 0.00182789045106822 1 1 -1.01950962625133 -3.44492264617922 1.39228666285197e-06 4374.7809550216 839.045094821982 5.2139997981274 2.85478680353363e-07 400.182914646627 1879.17400209353 0.212956817304196 0.831459724231553 C1QL1 other 0.00833840482382046 1 0.00259214641760854 5.2139997981274 0.212956817304196 0.136272417733736 89692.1222584204 79395.7701254512 1.1296838876517 0.259227730335822 -250089.325878387 177819.366344782 -1.40642344542763 0.160307494798347 GFAP other 1 1 1 1.1296838876517 -1.40642344542763 0.752121411403561 -4.50560038491175 16.3868686178002 -0.27495188312046 0.783482853515324 -27.2572507349612 36.7009802838142 -0.742684542052467 0.458070810241535 HIGD1B other 1 1 1 -0.27495188312046 -0.742684542052467 7.7312624634501e-06 235.426958843681 189.862439188117 1.23998701296794 0.215644087718083 -970.810614649745 312.343790764438 -3.10814763525076 0.00200527252503079 ATP6V1E1 essential 0.0434806200944434 1 1 1.23998701296794 -3.10814763525076 6.17788640746524e-34 158.517025430508 32.1356917984099 4.93274040667615 1.15533093234415e-06 -84.1130593254784 40.9143238183638 -2.05583403257236 0.040393404017436 ZNF227 other 5.67129972205309e-30 1 0.0103379011826154 4.93274040667615 -2.05583403257236 5.63952212705907e-33 750.474692852796 178.933182803742 4.1941616479037 3.32060248246836e-05 -487.740228484835 220.483435189231 -2.21214000982083 0.0274758563304978 ZNF428 other 5.16411041174799e-29 1 0.282118386910512 4.1941616479037 -2.21214000982083 0.00193765328874251 1.91485563159179 15.7134621438638 0.121860835890934 0.903066028675 -68.062549887719 24.4367531922824 -2.78525339893413 0.00558440112767279 ZNF141 other 1 1 1 0.121860835890934 -2.78525339893413 0.0181973411695225 947.638234716369 455.195350371082 2.08182758005731 0.0379382688915772 -949.771990433994 984.578997491761 -0.96464782699363 0.335253524480943 COX4I1 other 1 1 1 2.08182758005731 -0.96464782699363 3.28538419466203e-07 117.012222537487 28.390250162191 4.12156363078895 4.50168468429741e-05 -111.319834496864 61.407578131989 -1.81280288008743 0.0705466795723877 EMC8 other 0.00205336512166377 1 0.380347338976289 4.12156363078895 -1.81280288008743 0.01856059617357 482.387840477196 206.219198210983 2.33919947639241 0.0197737518616891 -284.935454497468 461.782674751574 -0.617033661236328 0.537533133076975 GSE1 other 1 1 1 2.33919947639241 -0.617033661236328 3.45861861705773e-08 195.043404244088 32.6593556797066 5.97205303610081 4.84979297756543e-09 181.727816195102 73.133465517638 2.4848790483103 0.0133319589616391 GINS2 essential 0.000229098897193904 1 4.53698133051246e-05 5.97205303610081 2.4848790483103 1.85432749321666e-11 582.957862503234 96.9224950482719 6.01468072208515 3.81223469869703e-09 -251.00668219328 205.949178507354 -1.21877972037804 0.223585318894926 CHMP1A essential 1.38944759066725e-07 1 3.57015779532977e-05 6.01468072208515 -1.21877972037804 0.771197289437276 -17.5652856625194 24.4146641199297 -0.719456371639405 0.472243465241164 -13.8927406691625 46.8215633404819 -0.296716719348643 0.766823442252369 F12 other 1 1 1 -0.719456371639405 -0.296716719348643 0.00577386454598233 -3.27841526754432 17.6633831971227 -0.185605171498423 0.852840318366137 -99.2914948320192 33.874199993445 -2.93118346267168 0.003553491946582 PRR7 other 1 1 1 -0.185605171498423 -2.93118346267168 3.46912021145394e-07 201.934835289107 43.9223050780752 4.5975463931174 5.65732138994783e-06 56.2475583427557 65.9942793230518 0.852309608040654 0.394525715888744 NFATC1 other 0.00216542483598955 1 0.0495977366256727 4.5975463931174 0.852309608040654 1.21230665415945e-67 207.496794225035 226.779756300404 0.914970531806085 0.360710532332356 -3072.41862648249 291.224343119831 -10.550006203356 2.44275190819289e-23 CAP1 essential 1.18175652647463e-63 2.40195795132607e-19 1 0.914970531806085 -10.550006203356 7.07993434257124e-40 401.417431554858 255.145556278273 1.57328795927394 0.11637418646314 -2172.80684021485 327.650925458516 -6.63146864967409 9.8111126945444e-11 PPT1 other 6.60911870879025e-36 9.27640705269173e-07 1 1.57328795927394 -6.63146864967409 2.18893712066661e-10 75.0058972198861 92.541655443247 0.810509568481676 0.418091578533584 -377.091905733159 108.009811230841 -3.49127455585704 0.000529964909046655 TRAF3 other 1.5928895427091e-06 1 1 0.810509568481676 -3.49127455585704 1.37732183748927e-06 174.620036448575 85.1630752234339 2.05041957433362 0.0409181546897668 -658.275253471594 182.80549166942 -3.60095994633464 0.000353329265481274 MRPS25 essential 0.00825428977207322 1 1 2.05041957433362 -3.60095994633464 0.241115413729651 -72.5156446520715 95.429682121288 -0.759885635581459 0.447731753682578 -345.704935958316 204.843119089695 -1.68765705919046 0.0921889787880473 SH3BP5 other 1 1 1 -0.759885635581459 -1.68765705919046 6.30979383439482e-07 81.7856977848505 26.7598780018352 3.05628066687156 0.00237806566642595 -163.780820862959 57.4410052984221 -2.85128750814982 0.00456008404635873 HACL1 other 0.00388367810507001 1 1 3.05628066687156 -2.85128750814982 3.11342612229943e-05 156.348921903005 220.974272141882 0.707543554222537 0.479605054212644 -1731.93679788812 455.289791131965 -3.8040316994196 0.000162584794856431 TBC1D5 other 0.164482302041079 1 1 0.707543554222537 -3.8040316994196 0.00322505283738081 136.120434302729 60.2783925042229 2.25819615699262 0.0244247770254954 -182.448794886931 129.389658016303 -1.41007247166496 0.159227995946824 CAPN7 other 1 1 1 2.25819615699262 -1.41007247166496 0.0035558242334543 584.858864674254 173.166706929344 3.37743250446455 0.000796994066439777 562.977638399137 356.788295147091 1.57790388882304 0.115309607220224 RFTN1 other 1 1 1 3.37743250446455 1.57790388882304 0.000209257882948553 238.49652198465 203.10112580593 1.17427474140415 0.240923055273652 -1377.77968633691 435.963603523673 -3.16030896891625 0.00168531633138316 RBSN other 0.992300880942038 1 1 1.17427474140415 -3.16030896891625 0.149555442242064 956.660702930812 779.044183883266 1.22799286962415 0.220109131690365 -1349.30930496945 1605.12289654719 -0.840626788062131 0.401015705096549 GALNT15 other 1 1 1 1.22799286962415 -0.840626788062131 0.412913607608864 -85.3773454144096 64.1679433012705 -1.33052956074282 0.184036138657521 -68.7850098821834 137.738713566047 -0.499387631126673 0.617757076869893 SLC6A6 other 1 1 1 -1.33052956074282 -0.499387631126673 0.000648413746236343 -159.03712971694 61.982952929937 -2.56582047481199 0.0106248867947155 -71.9648766564539 75.8085298726521 -0.949297879504391 0.342992616073699 KCNC3 other 1 1 1 -2.56582047481199 -0.949297879504391 4.0273451949676e-13 2.56218310902859 3.84242203538819 0.666814599081317 0.505241671156691 -14.0345635901683 4.69949158411866 -2.98640040926902 0.00298118988759548 NAPSA other 3.12803901293133e-09 1 1 0.666814599081317 -2.98640040926902 6.93453956337404e-06 79.0840194750711 139.02557133954 0.56884513196443 0.569753466432455 -298.359869224568 170.139920571312 -1.75361472030025 0.0801975825172078 NAPSB other 0.0391316067561197 1 1 0.56884513196443 -1.75361472030025 7.46846132450311e-62 357.630656653302 82.1983271257439 4.35082646032701 1.68928069570165e-05 -508.270527980875 100.53303437217 -5.05575636063338 6.31229671668694e-07 NR1H2 other 7.24366063863556e-58 0.005603425795403 0.145379496672084 4.35082646032701 -5.05575636063338 2.98676473354904e-24 639.027276758486 218.256010879163 2.92787939349026 0.003590727731264 -618.970048470622 266.938997555044 -2.31876965950989 0.0208669705368445 LRRC4B other 2.63223575967677e-20 1 1 2.92787939349026 -2.31876965950989 0.312786108613018 2.95751000121209 156.15037056164 0.0189401407795227 0.984897541702626 -431.611346829921 315.914785492072 -1.36622711772619 0.172573526945301 MGAT1 other 1 1 1 0.0189401407795227 -1.36622711772619 0.780668447420013 10.9810886168027 207.941496504956 0.0528085485647209 0.957908692520172 275.546732937329 420.695724428858 0.654978686344898 0.512827665647668 GFPT2 other 1 1 1 0.0528085485647209 0.654978686344898 0.0037060090927353 143.914667381496 46.4065345001856 3.10117247347828 0.00205235330755658 -47.8985167314476 101.643162489301 -0.471241897225398 0.63770316400361 TUBG1 essential 1 1 1 3.10117247347828 -0.471241897225398 0.00012444469339633 318.083098780327 99.5925308127076 3.1938449217493 0.00150547380897447 -422.986697493632 218.135223867584 -1.93910313975885 0.053132136122596 PSME3 other 0.609032329481641 1 1 3.1938449217493 -1.93910313975885 0.000101087782592193 2041.85080645161 528.652902679408 3.86236563935004 0.000129285986032439 -1235.1424731183 1196.07425625575 -1.03266370516564 0.302332457235761 RPL27 essential 0.501193226092095 1 1 3.86236563935004 -1.03266370516564 4.73675441057936e-05 123.10986016173 27.2790418605803 4.51298329284912 8.22872527247805e-06 63.8765022561768 59.7486563961443 1.06908683992263 0.285620710265633 PSMC3IP other 0.244416527585895 1 0.0717215694749187 4.51298329284912 1.06908683992263 0.944156309978791 -4.07863110396227 39.651111152948 -0.10286297118458 0.918118911659289 -29.4095407228697 86.8469144961539 -0.338636564044796 0.735046180097179 AOC3 other 1 1 1 -0.10286297118458 -0.338636564044796 0.0316849743861196 542.798145631501 315.155433671013 1.72231885488645 0.0857177002552841 -1037.08671255096 695.809697177124 -1.49047464667191 0.136819245568709 ACLY other 1 1 1 1.72231885488645 -1.49047464667191 0.000124588214820842 153.755484072736 39.0719540522418 3.93518798335897 9.66886133541878e-05 -53.5372157440906 85.578400052489 -0.625592622802645 0.531908746507297 VPS25 essential 0.609610135118381 1 0.803965820040072 3.93518798335897 -0.625592622802645 0.189898925710373 26.6812312916061 47.1529228146837 0.565844696339744 0.571789787468647 -158.278403252468 103.277959604572 -1.53254773679185 0.126110921558606 RAMP2 other 1 1 1 0.565844696339744 -1.53254773679185 0.157868004076817 3.97989545637315 3.87825443877632 1.02620792916024 0.305361277680359 -11.1335946924005 8.49445127374934 -1.31069027693489 0.190650815098112 AOC2 other 1 1 1 1.02620792916024 -1.31069027693489 0.0308682854242157 106.85012398784 82.4569233501396 1.29582962408285 0.195719759731541 -297.234394896696 174.313968511958 -1.70516681728984 0.0888756136805633 NDUFA2 other 1 1 1 1.29582962408285 -1.70516681728984 0.000932009096564726 207.002382272484 141.500033031498 1.46291402084977 0.1442113856348 -817.498693101152 299.131125685539 -2.73291083041805 0.00653299881848858 ANKHD1 other 1 1 1 1.46291402084977 -2.73291083041805 0.501615051018915 183.649445697159 159.702289837581 1.14994873200586 0.250795345986718 67.9695064183889 326.134925428442 0.208409161726846 0.835006826258983 DIAPH1 other 1 1 1 1.14994873200586 0.208409161726846 4.10919410664309e-05 9.51673145819012 383.720267204698 0.0248012218054496 0.98022486334668 -3157.23797545543 759.877135051721 -4.15493219866464 3.917168938366e-05 NDFIP1 other 0.214047921015039 0.32097282280971 1 0.0248012218054496 -4.15493219866464 0.170274434754777 447.027461936695 433.406486196901 1.03142771549018 0.302913403338135 -31.5026783211353 575.665217117453 -0.0547239565365433 0.956383507542415 ACAP3 other 1 1 1 1.03142771549018 -0.0547239565365433 2.44091819077344e-26 111.301935921617 17.5631094515286 6.33725686381407 5.86459314532811e-10 -8.79348533159629 23.338513640473 -0.376780006947266 0.706521245970324 C1orf159 other 2.17485810797914e-22 1 5.54145406302053e-06 6.33725686381407 -0.376780006947266 0.00245226124227639 404.875194122561 140.052119319178 2.89088944951881 0.00403303248528703 -194.54327439972 289.710218359727 -0.671509881498758 0.502250576679635 NINJ1 other 1 1 1 2.89088944951881 -0.671509881498758 6.63704952998949e-51 10.1107109558926 31.6341462271337 0.319613840161751 0.749413471418887 -358.461960460744 40.4431472660457 -8.86335472614649 1.96848370526198e-17 NPHP4 other 6.34634676057595e-47 1.92458651863464e-13 1 0.319613840161751 -8.86335472614649 1.70893395471944e-07 1953.86717598178 343.788082597869 5.68334760535381 2.41682130267571e-08 1133.89016217666 752.991110362717 1.50584800613444 0.132828654079417 TOP2A essential 0.00108739467538798 1 0.000223435129432369 5.68334760535381 1.50584800613444 0.0118126784539122 223.232222372157 75.0583730715756 2.97411485537107 0.00310106320401963 42.8632843071133 176.105622378665 0.243395319968535 0.807813380888971 STARD3 other 1 1 1 2.97411485537107 0.243395319968535 8.89237746054093e-05 420.95527476936 100.136113683844 4.20383075878525 3.18300102964813e-05 -12.5840352988332 219.323299807536 -0.0573766458460007 0.954271331763869 RARA og 0.44319609263336 1 0.27074606758187 4.20383075878525 -0.0573766458460007 0.0731325010428534 1030.88143750281 512.907147913892 2.00987925728007 0.0450581079522732 -827.496730085916 1203.40781194001 -0.687627853064963 0.492051955364326 PPP1R1B other 1 1 1 2.00987925728007 -0.687627853064963 1.48860628554635e-55 88.8343285202488 22.2172500083354 3.99843943273448 7.48236154847784e-05 -129.7806349551 27.862120416919 -4.6579597321779 4.24200383072894e-06 ZNF304 other 1.43323013172402e-51 0.0365278949864069 0.626124014376626 3.99843943273448 -4.6579597321779 2.23372396336442e-52 57.3271780553416 8.83771441546749 6.48665201887599 2.38013847525911e-10 -19.6857935055818 10.9824362193802 -1.7924796568218 0.0737477262949601 ZSCAN5A other 2.14080104648846e-48 1 2.25732332993574e-06 6.48665201887599 -1.7924796568218 1.55624702782393e-40 48.7862970943723 11.3547360639669 4.29655932287063 2.14090432046126e-05 -40.9346961483936 14.1004790681453 -2.90307130350414 0.00388274901940747 ZNF132 other 1.45477972160981e-36 1 0.183389864090711 4.29655932287063 -2.90307130350414 3.08199953332991e-08 83.7186612757582 51.291717232221 1.63220624680444 0.103358030413597 -387.483489664262 96.8539767629916 -4.00069777839336 7.41913820392892e-05 SELENOS other 0.000204983788961772 0.59597937192161 1 1.63220624680444 -4.00069777839336 0.0263813427368671 65.387592232536 78.1205237146559 0.837009138230711 0.403045968472078 -254.585835577286 147.51472161316 -1.72583341373146 0.0850858701644408 CHSY1 other 1 1 1 0.837009138230711 -1.72583341373146 4.49760540428431e-07 57.9483278873917 20.7101246836431 2.79806755258984 0.00536929083643685 -97.667029125369 39.1087512423996 -2.49731904043726 0.0128822199223771 SNRPA1 essential 0.00279076415335841 1 1 2.79806755258984 -2.49731904043726 0.424725250852998 -263.994374332955 272.02663517946 -0.970472520673552 0.332346616893602 189.173487809611 201.899971072449 0.93696639382741 0.349292180548352 LLGL1 other 1 1 1 -0.970472520673552 0.93696639382741 9.67163120808608e-27 319.254538370542 88.7393568388655 3.59766567781475 0.000357788931064811 -316.047029454233 114.755645278062 -2.75408698795103 0.00613119444232488 RHPN2 other 8.6396681581833e-23 1 1 3.59766567781475 -2.75408698795103 9.88321991949281e-27 112.26219339254 42.2960032691165 2.6542033458398 0.00824166394047455 -192.304637531281 53.9372392817351 -3.56534075700091 0.000403771004370155 C19orf12 other 8.82769203209098e-23 1 1 2.6542033458398 -3.56534075700091 4.67462772345252e-30 35.932180515815 4.69021588576531 7.66109309059063 1.19953577456483e-13 8.11135381572219 6.06527666683159 1.33734275636258 0.181806429066569 FAAP24 other 4.23147301526922e-26 1 1.15887151180708e-09 7.66109309059063 1.33734275636258 2.22256083891097e-22 181.13213596742 77.544655995496 2.33584292356575 0.0199519178084331 -384.536430051441 91.7755193419316 -4.18996735522421 3.37869213133279e-05 ACTR10 essential 1.93873981978204e-18 0.278269083936569 1 2.33584292356575 -4.18996735522421 0.491269487316878 -7.8746537944139 6.65318202153687 -1.18359211711374 0.237217999559181 -6.65921500356164 8.75942039691527 -0.760234661862646 0.447524286859484 ABHD12B other 1 1 1 -1.18359211711374 -0.760234661862646 0.0420808523617683 -9.30560501388798 15.7555543206429 -0.590623777780753 0.555079250172955 21.321700733566 19.6133898451265 1.08709921650102 0.277594953145715 GCH1 other 1 1 1 -0.590623777780753 1.08709921650102 0.248197477430321 -372.761826080764 308.754463941952 -1.20730829709023 0.227969487954173 -80.7214941955708 384.354719895977 -0.210018220193621 0.833751782488615 LGALS3 other 1 1 1 -1.20730829709023 -0.210018220193621 0.0039519231456171 47.2217488743965 41.106361184162 1.14876986223219 0.251279279397268 -58.9059843727915 48.470311971584 -1.21530029365863 0.224907749723828 TRIM21 other 1 1 1 1.14876986223219 -1.21530029365863 3.18521445768252e-32 68.3169311069528 73.0524843897244 0.935176013213896 0.350215252970387 -582.996824778878 93.8805771335414 -6.20998339144835 1.23665437260408e-09 SPATA6 other 2.90682671408107e-28 1.15738482732016e-05 1 0.935176013213896 -6.20998339144835 1.61959342056818e-107 178.232643540479 68.4513301531612 2.60378641498536 0.00953321584459115 -1219.43208018339 87.8981773010065 -13.8732351184877 1.56032927306707e-36 LRRC41 other 1.59594735662788e-103 1.53739243275298e-32 1 2.60378641498536 -13.8732351184877 0.0116400511583845 -1.27041922243222 7.93845846145421 -0.160033491212537 0.872928467424204 -50.1876815938755 17.1025684470082 -2.93451137174984 0.00351634412400361 CCT6B other 1 1 1 -0.160033491212537 -2.93451137174984 2.4245744440364e-12 299.549812451353 152.75075220736 1.96103657836469 0.0505094174529621 -1073.00775260091 237.770506065009 -4.51278743675439 8.23599045462683e-06 DHX30 other 1.8521324177994e-08 0.0700388628261466 1 1.96103657836469 -4.51278743675439 1.48962848670678e-05 479.522831694858 142.483193350965 3.36546943128721 0.000831447877021067 -525.604199286427 305.845111238833 -1.71853065480581 0.0864065100695024 RAF1 og 0.0814379893682596 1 1 3.36546943128721 -1.71853065480581 0.754094735086845 -333.087345254471 449.029512155629 -0.741793882668066 0.458610703106043 -402.612888487028 991.987716947381 -0.405864792082283 0.68504060003731 SLC6A11 other 1 1 1 -0.741793882668066 -0.405864792082283 0.575703026026263 -3.29649118303857 8.07170951126357 -0.408400621756584 0.683179160574394 12.4372186144408 17.326204131873 0.717827085481551 0.473246589855889 PPARG other 1 1 1 -0.408400621756584 0.717827085481551 0.376999837456176 -61.8065145409261 124.632657549802 -0.495909465111331 0.620207027725174 -373.468076696011 267.528317662123 -1.39599456221934 0.163423293502384 NUP210 other 1 1 1 -0.495909465111331 -1.39599456221934 3.59788218083909e-07 287.356881851402 53.8896260738367 5.33232280100962 1.56326026548549e-07 168.153942870615 104.538933665276 1.60852934858727 0.108446451872741 ENOSF1 other 0.00224363932797125 1 0.00142553703609622 5.33232280100962 1.60852934858727 0.535438116353699 55.2384470382479 54.4476370032333 1.01452423059182 0.310892759393322 100.031147026183 106.030549182207 0.943418173325548 0.345987135103622 EMILIN2 other 1 1 1 1.01452423059182 0.943418173325548 6.66598558755064e-43 334.923318639932 48.9028500545816 6.84874845261812 2.53133308186049e-11 -267.985663756188 59.0889779842857 -4.53529021651816 7.43604594872598e-06 ARFIP2 other 6.27002604365013e-39 0.0633625475290941 2.4169168265604e-07 6.84874845261812 -4.53529021651816 0.000474863352558212 -37.2521507424179 45.6709630235449 -0.815663788898281 0.415135787713103 -171.922233422867 54.1936355323189 -3.17236944401598 0.00161838131282843 TRIM5 other 1 1 1 -0.815663788898281 -3.17236944401598 0.00778174638899423 -4.01048456555325 4.71391961877183 -0.850774915546428 0.395359253502699 -14.8364411125002 5.5996133733127 -2.6495474103997 0.00835151334209317 CNGA4 other 1 1 1 -0.850774915546428 -2.6495474103997 0.0589823678675779 -214.28124158584 235.528771771283 -0.909787963374275 0.363434708786629 -599.471702140239 279.480868580924 -2.14494718434246 0.0325064659092156 TRIM22 other 1 1 1 -0.909787963374275 -2.14494718434246 2.56664322518679e-32 126.534646966862 22.060297032911 5.73585418084304 1.81130017639743e-08 -102.095135827766 26.6553054525368 -3.8301994328881 0.000146732899655669 RRP8 other 2.34411525756309e-28 1 0.00016785318734675 5.73585418084304 -3.8301994328881 5.9693908051943e-25 144.88872493272 46.1535855328221 3.13927343368983 0.00180821011944724 -282.158555535716 55.7670605373902 -5.05959168040669 6.19353307314201e-07 TIMM10B other 5.28171698443592e-21 0.00550047672225742 1 3.13927343368983 -5.05959168040669 0.00285066318387207 105.907061392866 53.0224838839194 1.9973990962914 0.0463999565985918 -51.7212268079787 80.6853001379324 -0.64102416077725 0.521842240481338 IQCA1 other 1 1 1 1.9973990962914 -0.64102416077725 7.56459774481729e-14 227.119757916616 44.9836161730091 5.0489439764714 6.54541948477974e-07 -70.0066501885181 68.4723610828128 -1.02240742222763 0.307156352436242 ILKAP other 5.96771116088636e-10 1 0.00589742295578654 5.0489439764714 -1.02240742222763 2.9117958489711e-08 -83.5769512195142 53.6590193296954 -1.55755644183497 0.120063973903252 -429.942531311802 81.6697586300344 -5.26440310983959 2.21229074855274e-07 PER2 other 0.000193896485582986 0.00199084044462261 1 -1.55755644183497 -5.26440310983959 2.40614091746469e-07 312.58323222519 354.001693500869 0.882999256681302 0.377721042796565 -1825.41143254393 538.690962724144 -3.38860600763168 0.000766019428819445 RAMP1 other 0.00151683123436974 1 1 0.882999256681302 -3.38860600763168 1.18305098231704e-17 60.3238170925545 19.4333526757153 3.10413844173876 0.00203291370360441 -121.958478040333 29.5807152618297 -4.12290497240633 4.48192563311596e-05 SCLY other 9.86191298859489e-14 0.366083685712911 1 3.10413844173876 -4.12290497240633 6.18310229892878e-12 59.8302225286122 187.139876647865 0.319708570938052 0.749342049572015 -769.874298863124 217.282486396996 -3.54319536576219 0.000437888004888405 PTPRE other 4.68060844028909e-08 1 1 0.319708570938052 -3.54319536576219 2.66153324430787e-09 901.44982964569 149.758610275273 6.0193522628764 3.71810145566134e-09 -124.230442921201 278.072661297314 -0.446755327696073 0.655273552902488 RAN essential 1.86546865093539e-05 1 3.48386106395468e-05 6.0193522628764 -0.446755327696073 0.000867904187458022 93.6812882713143 54.6890299715366 1.71298134781457 0.0874301560270354 -243.321910818024 116.341064844077 -2.09145335865826 0.0370682346153293 PRKAA1 other 1 1 1 1.71298134781457 -2.09145335865826 0.48762977611873 -22.9596679227509 19.9874719614657 -1.14870294587607 0.251311191340714 -11.3214005338364 42.5197479777628 -0.2662621739846 0.790163752943734 CARD6 other 1 1 1 -1.14870294587607 -0.2662621739846 0.000203814721203501 -199.49940223626 138.392487439267 -1.44154791873229 0.150144516399609 -384.310033792656 100.855403065511 -3.81050515997667 0.000158519255647068 RAP1GAP2 other 0.968850771996106 1 1 -1.44154791873229 -3.81050515997667 0.00838193594557032 178.565270272141 94.067920348476 1.89825893472125 0.0583190722742853 -176.435192735615 68.5532733591725 -2.57369464782834 0.0103897118876982 CLUH other 1 1 1 1.89825893472125 -2.57369464782834 4.03039107063426e-06 274.515200244401 55.3426187420975 4.96028569814651 1.01134838109834e-06 28.0957257123815 39.3389344910789 0.714196408109449 0.475488785783251 INPP5K other 0.0232996907793367 1 0.00906572688816554 4.96028569814651 0.714196408109449 0.00888559682055195 225.380557820686 78.0796094426935 2.88654822212071 0.00408757267018504 -72.6531899161057 56.9015748415991 -1.27682212870831 0.202341545974469 MYBBP1A essential 1 1 1 2.88654822212071 -1.27682212870831 2.14047288231535e-07 633.953493125142 116.259118609753 5.45293565533672 8.29455002153882e-08 91.9575550074183 89.242557216863 1.03042268033577 0.303380285282443 RPA1 essential 0.00135406314535269 1 0.000760278454974248 5.45293565533672 1.03042268033577 0.00529236269807261 -2008.6791074 657.866115450017 -3.05332507667757 0.00240111537703776 686.707053025233 504.98967436829 1.35984375103166 0.174578927723783 SERPINF1 other 1 1 1 -3.05332507667757 1.35984375103166 0.99409695541758 -0.00810954625198525 43.8764696137613 -0.000184826772148546 0.999852613721449 3.47340642406023 31.9755725897297 0.108626871788243 0.913548191353009 UBE2G1 other 1 1 1 -0.000184826772148546 0.108626871788243 4.47872844165442e-06 91.3541982627883 44.662328844314 2.04544188864927 0.0414109735376131 -297.93956195466 91.251958995035 -3.26502099501087 0.00118084600397816 EEFSEC essential 0.0257929970954878 1 1 2.04544188864927 -3.26502099501087 6.76580800125627e-07 -196.719879569364 311.858586277473 -0.630798343305303 0.528502138968352 -2358.87471410492 495.364032550754 -4.76190146861991 2.61274063035047e-06 TBC1D14 other 0.00414879346637034 0.0226864268933331 1 -0.630798343305303 -4.76190146861991 4.58583262887293e-10 55.5141221711461 28.046918518927 1.97933053264597 0.0484045262442401 -185.860457920793 44.9517291319953 -4.13466759810365 4.26149924129344e-05 TMEM128 other 3.31188832457203e-06 0.348505407952978 1 1.97933053264597 -4.13466759810365 1.98872185993606e-10 14.7452508361207 14.3779478278733 1.02554627493747 0.305672839467347 -72.5260626330193 19.3458936585503 -3.74891250376355 0.000201472611064138 COQ3 other 1.45037485245137e-06 1 1 1.02554627493747 -3.74891250376355 1.83434852051223e-08 300.158896321107 358.325228020152 0.837671681616083 0.402673016932134 -1635.43914259651 482.135687195565 -3.39207236889962 0.000756788451667913 PNISR other 0.000123671777252934 1 1 0.837671681616083 -3.39207236889962 0.327616445396393 18.5744576647162 15.3998968763665 1.20614169132662 0.22841545221799 6.80717928034257 20.5005775527098 0.332048170976665 0.740012086129956 POPDC3 other 1 1 1 1.20614169132662 0.332048170976665 2.61104049835942e-10 255.166689787195 128.937196174419 1.97899983370213 0.0484418844699584 -692.364129881901 191.653245437752 -3.61258755780778 0.000338292192531694 GRSF1 essential 1.89639871395845e-06 1 1 1.97899983370213 -3.61258755780778 0.848496036852281 -29.3192020642012 115.037288421355 -0.254866943288961 0.798945492053945 -94.8228504841438 170.992315068547 -0.554544515325917 0.579489291851578 JCHAIN other 1 1 1 -0.254866943288961 -0.554544515325917 3.18736140137805e-05 78.646394584242 200.456667312531 0.392336137473664 0.69500070916067 -953.3309195498 297.9603403824 -3.19952285705642 0.00147656993883351 ANKRD17 other 0.168228934764733 1 1 0.392336137473664 -3.19952285705642 1.14465734170717e-18 10.2325833032753 25.641218056055 0.399067754149025 0.690037776266799 -263.634293297821 38.1133047966416 -6.91711974871965 1.64131796454183e-11 UTP3 essential 9.65976330666684e-15 1.56384775661546e-07 1 0.399067754149025 -6.91711974871965 2.63721803427553e-31 207.964618616031 95.1285174805602 2.18614379918755 0.0293349352008846 -607.753394639525 122.219571359337 -4.97263562521154 9.50698058849589e-07 ZRANB2 other 2.39802235856674e-27 0.00838895967128877 1 2.18614379918755 -4.97263562521154 2.07026981113306e-06 1265.74297154638 254.452858892347 4.9743711941625 9.41917102415751e-07 250.129740383308 190.203863465504 1.31506130225726 0.189177361887063 EIF5A essential 0.0122415053932298 1 0.00845464791128378 4.9743711941625 1.31506130225726 0.741315475387776 32.446570159939 101.39082496427 0.320014855105213 0.749109666684582 52.5148837841506 75.7897816990843 0.692901900584113 0.488738340485714 KDM6B other 1 1 1 0.320014855105213 0.692901900584113 1.81604370093952e-06 407.679200081559 79.4995523329172 5.12806912892209 4.40344124994942e-07 47.1832268587739 59.4260251715083 0.793982547589197 0.427635537903018 GPS2 other 0.0107826004976104 1 0.00398115123407927 5.12806912892209 0.793982547589197 0.0121571620139898 -55.427642607946 164.712278800674 -0.336511904343341 0.736646040706383 -363.448076661682 123.122655899692 -2.95191875131238 0.00332774842778301 XAF1 other 1 1 1 -0.336511904343341 -2.95191875131238 0.000290918509893572 -398.304052829511 337.741505512287 -1.17931627096102 0.238912445744911 -973.079176294685 252.462241849957 -3.85435528562328 0.000133405978908997 DLG4 other 1 1 1 -1.17931627096102 -3.85435528562328 5.56981033533363e-06 160.001488881417 38.6061024439425 4.14446107616653 4.09336041318187e-05 -130.394569585193 81.7537176493327 -1.59496807404522 0.111443956406096 SDF2 other 0.031753488721737 1 0.34638015816345 4.14446107616653 -1.59496807404522 0.0517943673329727 328.582434285163 151.099400004912 2.17461111211878 0.0301962259436184 523.697911054453 330.350046527149 1.58528178385292 0.113627315523584 FLOT2 other 1 1 1 2.17461111211878 1.58528178385292 1.07595460110274e-07 265.039321585478 55.9138489581593 4.74013730987842 2.89625201596969e-06 -256.580905574752 122.244976513735 -2.09890756162012 0.0363995908471868 ERAL1 essential 0.000691408426668624 1 0.0256550003574595 4.74013730987842 -2.09890756162012 0.00350507959556001 190.184143742839 61.2912014217178 3.10295995724192 0.00203997776735159 -23.7746986618688 141.458298040607 -0.168068603900806 0.866606884805028 PRMT7 other 1 1 1 3.10295995724192 -0.168068603900806 6.69396243664109e-07 92.8636740227455 20.0267470541855 4.63698242013485 4.67927981206027e-06 -45.6439707765304 46.2227049472589 -0.987479439565712 0.323955333072104 NIP7 essential 0.00410741535112297 1 0.041149586667258 4.63698242013485 -0.987479439565712 1.08695091010373e-07 168.183098591548 58.3712064099152 2.88126816174523 0.00415626897915265 -492.70020120724 134.723579620843 -3.65711928523471 0.000286229107032703 TERF2 essential 0.000698039874468612 1 1 2.88126816174523 -3.65711928523471 5.93827435567251e-11 481.123823152817 93.5338181333659 5.14384885332921 4.07580588574583e-07 -581.860761718254 215.880595409306 -2.69528977634629 0.00730465637533585 VPS4A other 4.39432302319765e-07 1 0.0036898270683657 5.14384885332921 -2.69528977634629 0.128201188201694 -930.723852269013 1496.74582066833 -0.621831602545196 0.534376133785299 -7254.71585587823 3572.17231000758 -2.03089751173365 0.0428688650397061 MTSS1L other 1 1 1 -0.621831602545196 -2.03089751173365 4.92360408186392e-08 103.966946059698 18.4362357847926 5.63927188138137 3.07816971757723e-08 -2.27396769174497 49.821530911921 -0.0456422685156965 0.963616324036245 NXT1 other 0.000323185371933548 1 0.0002839611564465 5.63927188138137 -0.0456422685156965 4.37365489196856e-27 737.500183882565 234.332179784341 3.1472424511277 0.00176071242013692 -1051.1981502968 302.353392525143 -3.47672020981005 0.000558266540787801 MMACHC other 3.91267166635507e-23 1 1 3.1472424511277 -3.47672020981005 2.34196707983798e-47 98.7622251689475 24.5052340150844 4.03025023585385 6.56993629207886e-05 -167.184302126821 31.6185367536892 -5.28754076854345 1.96090907112757e-07 DPH2 other 2.22369774230616e-43 0.00176619080036461 0.551086256179574 4.03025023585385 -5.28754076854345 5.64660346176019e-54 76.0372021188797 11.8169917481943 6.43456505167642 3.25198242453625e-10 -56.2436184980677 15.2471911787633 -3.68878554998415 0.000253671096411509 TOE1 essential 5.42864456813625e-50 1 3.08092814900564e-06 6.43456505167642 -3.68878554998415 5.2652834363206e-33 1221.69353165024 208.371012798705 5.86306854893703 8.95526660141172e-09 -397.386098996154 268.856299128741 -1.47806132972866 0.140110083061109 NASP essential 4.8235261560133e-29 1 8.3436218925353e-05 5.86306854893703 -1.47806132972866 6.57944781621755e-33 109.420661148463 21.6658601202942 5.05037236190637 6.48273887709166e-07 -65.5896310953181 27.9549582792039 -2.34626109759253 0.0194077242140857 MUTYH ts 6.02216858618392e-29 1 0.0058415960021473 5.05037236190637 -2.34626109759253 0.00711784020442554 37.0924206843291 44.3239705901522 0.836847876904112 0.403134427370985 -52.7007351486143 56.9162968330992 -0.925934013295937 0.354990160720455 PATJ other 1 1 1 0.836847876904112 -0.925934013295937 0.220239511768962 -14.2106810194014 8.57937339082244 -1.65637749659001 0.0983615514336084 -12.2207074448245 11.0167513436293 -1.10928413137794 0.267916307919394 KANK4 other 1 1 1 -1.65637749659001 -1.10928413137794 0.0498370334322688 -466.316274343424 189.980235506202 -2.45455151216612 0.0144958886280701 -445.645568161585 321.386775261718 -1.38663318613119 0.166262213648286 SYT4 other 1 1 1 -2.45455151216612 -1.38663318613119 0.148573211314044 -38.895657672399 25.3622926862915 -1.53360179828784 0.125852926409921 -78.0941012106047 40.8374751041678 -1.91231463285629 0.0564908462999096 SLC14A2 other 1 1 1 -1.53360179828784 -1.91231463285629 4.81340521795605e-13 -184.347767648509 144.924672154795 -1.27202473469532 0.204039264128628 -951.994469639621 185.170500467947 -5.14117781846365 4.12330743836056e-07 FBXO44 other 3.7342397680903e-09 0.00368623684989434 1 -1.27202473469532 -5.14117781846365 3.66728034355906e-05 -9.17736940555468 6.80691184655821 -1.34824272921869 0.178278712796992 -30.1576908209552 8.70130927300759 -3.4658796595712 0.000580756568442773 RSG1 other 0.191982125985317 1 1 -1.34824272921869 -3.4658796595712 3.89201932924532e-14 177.431336466714 94.2514872937635 1.88253089220434 0.0604265668457195 -315.398919249051 120.431882643816 -2.61889885240655 0.00912737758656344 CASP9 other 3.08792813582324e-10 1 1 1.88253089220434 -2.61889885240655 0.426436379004112 4.36336546072539 16.7034450404807 0.261225480740698 0.794041413160598 -29.5199282953858 30.3608882551573 -0.972301206977084 0.331437361300104 NMUR2 other 1 1 1 0.261225480740698 -0.972301206977084 6.30833620535283e-05 292.131107613914 222.843297612988 1.31092615637585 0.190571170774469 -1415.74126948442 429.276418143595 -3.2979712130631 0.00105343918348378 DCTN4 essential 0.320652729318084 1 1 1.31092615637585 -3.2979712130631 0.96921933774947 -9.74897382103423 72.2970370083125 -0.134846104687711 0.892795495983462 -33.7564665563386 135.839142840637 -0.248503235889384 0.803861538853578 PDE6A other 1 1 1 -0.134846104687711 -0.248503235889384 0.3530553516278 -58.2348816685194 140.34460838001 -0.414942065396892 0.678388414591813 -212.052762959968 172.685652573361 -1.22796978092829 0.220120813860811 ATP8A2 other 1 1 1 -0.414942065396892 -1.22796978092829 0.519325322424202 -20.8916455063895 25.5440194249684 -0.8178683690621 0.413882176312081 -35.5404835247173 31.0660683460914 -1.14402901354554 0.253243645356566 MTUS2 other 1 1 1 -0.8178683690621 -1.14402901354554 1.7562241581762e-13 18.5948807026731 17.1441004331923 1.08462271176806 0.278700790859086 -92.6278185631892 21.3356999078631 -4.34144738458062 1.76954185662299e-05 ZMYM5 other 1.37512351585196e-09 0.147916003795116 1 1.08462271176806 -4.34144738458062 2.69565724587064e-13 52.0741733952386 57.1025103683158 0.911941927935496 0.362306718852617 -308.982697948933 69.3241731055677 -4.45707008258736 1.05956216351775e-05 USPL1 essential 2.10288221750369e-09 0.0896495546552367 1 0.911941927935496 -4.45707008258736 4.20563142913483e-14 72.6350848324117 59.083985199696 1.22935317560105 0.219610124131663 -307.085062466051 72.8477672935079 -4.21543547421003 3.03907997967827e-05 XPO4 other 3.33464516016101e-10 0.250997615521628 1 1.22935317560105 -4.21543547421003 2.03204662785927e-13 97.4768112726089 93.114442339908 1.04684954152199 0.295751638127492 -494.051019871879 113.029563044961 -4.37098938155991 1.5495975430412e-05 POMP other 1.58845084899759e-09 0.129840778131422 1 1.04684954152199 -4.37098938155991 2.40222564465369e-07 106.359070984571 47.2005255270752 2.25334505912569 0.0247347002292911 -101.862928811805 58.1910942199384 -1.75049000499639 0.0807387547972875 CDK8 other 0.00151460326895415 1 1 2.25334505912569 -1.75049000499639 0.0094377540869352 -79.5744266316897 120.039624521839 -0.662901329029172 0.507746469020969 214.760089935536 145.7317315159 1.47366731803433 0.141297781279751 ALOX5AP other 1 1 1 -0.662901329029172 1.47366731803433 1.73846895956158e-10 -117.771502042027 451.901793057822 -0.260613044363288 0.794514536669912 -2644.4121312963 553.913854551207 -4.7740494475244 2.47241094194859e-06 WASF3 other 1.26995157495974e-06 0.0214951407293011 1 -0.260613044363288 -4.7740494475244 0.393081803060004 -23.3731424051951 32.613817580744 -0.716663798935184 0.473967933963556 -51.8970138736094 39.6641996364909 -1.30840945611479 0.191428548768242 GPR12 other 1 1 1 -0.716663798935184 -1.30840945611479 0.950909278964974 23.2478390215673 73.2746408637655 0.31726991422299 0.751189984408875 15.04374018676 144.793819835854 0.103897667758295 0.917298113966193 CHRM3 other 1 1 1 0.31726991422299 0.103897667758295 0.51803327495916 229.622745910926 242.47779185765 0.946984646106187 0.344168751121192 111.368764442028 181.252484317426 0.614439933672791 0.539243686976259 MYH10 other 1 1 1 0.946984646106187 0.614439933672791 0.00240193702579146 84.1924274398104 33.3070373591353 2.52776692601026 0.0118296767368873 -63.4165116013142 24.7207038196169 -2.56531982519812 0.0106399988844548 PEMT other 1 1 1 2.52776692601026 -2.56531982519812 6.84721075806311e-09 51.546325600971 26.3648607102369 1.95511465687193 0.0512184706503278 -122.811821494261 20.2211680514919 -6.07342865563102 2.76146081593679e-09 SCO1 other 4.71498932800226e-05 2.57036772747396e-05 1 1.95511465687193 -6.07342865563102 0.0636740504194677 -271.215764342244 317.703852308417 -0.853674774075312 0.393751836609577 528.598358213095 235.801904281756 2.2417052136334 0.0254803937311507 MPRIP other 1 1 1 -0.853674774075312 2.2417052136334 0.000449982999733043 -422.720368525859 777.921845932939 -0.543396962992989 0.587133592878847 -2694.76726883671 927.887961194508 -2.90419466739026 0.00386867774116938 DCLK1 other 1 1 1 -0.543396962992989 -2.90419466739026 0.171447139895402 17.1649498912295 13.8778204151675 1.23686208480327 0.21680256056822 30.9786496529704 16.6812519916829 1.85709380017856 0.0639704117299062 CCNA1 other 1 1 1 1.23686208480327 1.85709380017856 5.75007809674357e-14 155.188723762793 45.5412260019554 3.40765362259087 0.000715788609165584 -113.630443478493 55.0691463162171 -2.06341392739241 0.0396619848895261 COG6 other 4.54428671985644e-10 1 1 3.40765362259087 -2.06341392739241 0.704341509102306 -41.62320564881 59.8690766733866 -0.695237140133023 0.487276213604631 -17.5321780513652 71.7650712305045 -0.244299597990408 0.807113453503604 EPSTI1 other 1 1 1 -0.695237140133023 -0.244299597990408 0.0783591101632593 25.2685477985892 16.9359256761692 1.49200866145421 0.136416758990859 1.05888962249952 20.5088976840395 0.0516307428518488 0.958846460615302 TRPC4 other 1 1 1 1.49200866145421 0.0516307428518488 0.93924166097087 -348.192653855507 1197.5691776683 -0.290749511884939 0.771380520872324 -135.18418387112 1450.22033067366 -0.0932163072133483 0.925774342449522 POSTN other 1 1 1 -0.290749511884939 -0.0932163072133483 7.11782314214454e-22 63.5920272204987 19.5227610730692 3.25732753592017 0.00121232808018111 -89.5873417250796 23.4665161596525 -3.81766688824109 0.000154179873544867 RFXAP other 6.18752365746625e-18 1 1 3.25732753592017 -3.81766688824109 2.53341432276336e-08 3000.35573481835 2076.88187787502 1.44464438097375 0.149272780515251 -6356.45974416857 2485.95670543035 -2.55694708209658 0.0108955881071867 TPT1 essential 0.000169206742617365 1 1 1.44464438097375 -2.55694708209658 5.46292927287669e-25 196.251082083585 42.8045376362315 4.58481957570476 5.93699740127285e-06 -151.416322308719 51.3029400637873 -2.95141608103661 0.00333306225732185 GPALPP1 other 4.83523869942316e-21 1 0.0519665382533413 4.58481957570476 -2.95141608103661 0.870380589806003 -4.84197436020571 51.1494370241075 -0.0946632972308887 0.924625760452656 -24.4970951169156 61.0177286277278 -0.401475041235534 0.688267112799408 KL other 1 1 1 -0.0946632972308887 -0.401475041235534 8.58288947356958e-06 123.474086522303 36.1772729873764 3.41302912923778 0.000702460142093691 18.1363408761982 43.1569759916332 0.420241234689712 0.674516262469407 RFC3 essential 0.0480470152730425 1 1 3.41302912923778 0.420241234689712 0.000665700818388299 26.3108849090112 46.1510708217551 0.570103454600852 0.568901180294119 -108.65710032993 55.0550246321121 -1.97360914931919 0.0490571747521855 STARD13 other 1 1 1 0.570103454600852 -1.97360914931919 1.27779564191246e-13 385.871615321573 89.769469960428 4.2984726933519 2.12425829574722e-05 7.35061466324525 114.84953145193 0.0640021301812782 0.948997930529945 EPHB2 other 1.004219594979e-09 1 0.182006450779622 4.2984726933519 0.0640021301812782 3.22922298198764e-57 162.138392818205 83.2483299104393 1.94764739415959 0.0520957157232852 -894.436033194525 106.889256680323 -8.36787588363104 7.94313271677609e-16 SRRM1 essential 3.11587725531987e-53 7.73422832632488e-12 1 1.94764739415959 -8.36787588363104 3.93848566153437e-28 87.9400469875291 24.7587480788356 3.55187777295987 0.00042438159464225 -64.4642250717243 30.6539286573648 -2.10296780527792 0.0360438064499259 KMT5C other 3.54030476115324e-24 1 1 3.55187777295987 -2.10296780527792 0.456798374043509 9.35280063004921 44.1388455830863 0.211894998758942 0.832289117821087 -59.4179872500284 68.6424204819398 -0.865616142799941 0.387182268004158 PDE6B other 1 1 1 0.211894998758942 -0.865616142799941 1.10638662701876e-34 531.247824370463 90.9307316828197 5.84233530885396 1.01123757156804e-08 -50.7905290965306 112.519976873978 -0.451391215209861 0.65193308318079 HSPBP1 other 1.01776505819455e-30 1 9.4125993161553e-05 5.84233530885396 -0.451391215209861 1.69692821825905e-08 48.9838205973556 298.432013877851 0.164137285275985 0.86969930743795 -1925.60798310205 444.814639084139 -4.32901216350888 1.86061701032468e-05 CNDP2 other 0.000114644470425581 0.155324308021905 1 0.164137285275985 -4.32901216350888 1.73192991407311e-08 74.0827391184939 31.1501375669911 2.37824757464305 0.0178251237410258 -147.567394643421 50.4998644262552 -2.92213447144821 0.00365715596499959 MED10 other 0.000116957227097357 1 1 2.37824757464305 -2.92213447144821 0.0215571608878121 -610.218779790265 370.051196646606 -1.64901177274943 0.0998704990637654 -2205.14772310622 798.482461158611 -2.76167333707809 0.00599522850103123 PDZD2 other 1 1 1 -1.64901177274943 -2.76167333707809 2.45109583580007e-08 235.347545003981 78.1382185651038 3.01193896310666 0.00274686811816756 -298.647206671629 123.399299108798 -2.42016939179143 0.0159211215681371 MORC2 other 0.000163831245664877 1 1 3.01193896310666 -2.42016939179143 3.16442962034329e-10 68.6022283033613 89.0591846281946 0.770299308148428 0.441539540499061 -704.530688037526 141.599857863166 -4.97550420367191 9.382283288954e-07 LARGE1 other 2.29452791771092e-06 0.00828455614414638 1 0.770299308148428 -4.97550420367191 0.00697294470814552 -50.3424318084875 58.6072221545715 -0.858980002084276 0.390821397736849 -276.450518807558 93.1660869579163 -2.96728700146474 0.0031689774159525 GSTT2B other 1 1 1 -0.858980002084276 -2.96728700146474 1.16009523926482e-10 70.0274773531407 29.7869276206649 2.35094663823464 0.0191681477075295 -183.494008933275 47.3513568276083 -3.87515841629039 0.000122854053125265 SLC2A11 other 8.52089953240007e-07 0.969564187264592 1 2.35094663823464 -3.87515841629039 0.0203161295125461 62.5419733924623 28.7903804144091 2.17232188294257 0.0303682779665845 -2.61159645232709 44.7793800241381 -0.058321407105666 0.95351927476163 C1QTNF6 other 1 1 1 2.17232188294257 -0.058321407105666 0.928155904838228 1.20447058665999 34.6706435734959 0.0347403584853196 0.972302641359522 -16.2298699733517 55.9079096338068 -0.290296490776641 0.77172712722123 NTS other 1 1 1 0.0347403584853196 -0.290296490776641 0.0159443451244697 403.894867228204 207.07275866296 1.95049735096058 0.0517557504570141 -191.866679164922 333.913763510348 -0.574599492838742 0.565857866632856 BTG1 other 1 1 1 1.95049735096058 -0.574599492838742 0.860044897933901 11.6289229201077 34.5836377920472 0.336255051884156 0.736839940705425 -7.59792333151153 54.4283773182311 -0.139594889759217 0.889044390459382 LRRIQ1 other 1 1 1 0.336255051884156 -0.139594889759217 3.26332170140739e-09 24.8163616654973 36.6353330464221 0.677388728363723 0.498518617260774 -279.923641757587 59.079428790566 -4.73808984765076 2.9242099829553e-06 C12orf29 other 2.27453522588095e-05 0.0253382795023076 1 0.677388728363723 -4.73808984765076 0.000656670956420547 135.675876569231 92.2614140199741 1.47055925828167 0.142128345556573 -383.741423587311 168.809231236383 -2.27322534897371 0.0234960619298401 ATP13A3 other 1 1 1 1.47055925828167 -2.27322534897371 0.0616715962033434 -7.90085025980253 9.73611809240421 -0.811499016837779 0.417520931398587 -23.2618017831848 11.8045693452861 -1.97057606277469 0.0494031622320164 SFTPD other 1 1 1 -0.811499016837779 -1.97057606277469 0.00168462038323429 -8.70899835033404 14.1666076655683 -0.614755385052494 0.539036965608643 27.3088703514561 17.1526035135205 1.59211226038834 0.112084195843799 DYDC2 other 1 1 1 -0.614755385052494 1.59211226038834 6.98699153231485e-10 -30.895276334435 41.0462365953225 -0.752694495211181 0.452038782059498 -224.866726204536 49.7665642152105 -4.51842978816304 8.0291349669134e-06 TMEM254 other 5.00617943290359e-06 0.0683038511635323 1 -0.752694495211181 -4.51842978816304 8.18568514850375e-06 522.518250395441 208.764141295342 2.5029118849306 0.0126816566322761 -1182.61089143042 413.402528929492 -2.86067648036116 0.00443011117122863 LARS essential 0.0459380650534031 1 1 2.5029118849306 -2.86067648036116 4.70942378061548e-06 45.6949957190139 19.1350593543148 2.38802477028691 0.0173620564063344 -64.1663514497849 30.4690841752631 -2.10594946276329 0.0357772649619859 CCDC59 essential 0.0270509301958553 1 1 2.38802477028691 -2.10594946276329 0.237918824507529 -152.239063894911 103.592623103673 -1.46959367697981 0.142389732510652 -207.037877821704 125.534990122699 -1.64924438691829 0.0998145507109472 SWAP70 other 1 1 1 -1.46959367697981 -1.64924438691829 0.00191331387450842 33.1411016258888 50.9450499071011 0.650526433604874 0.515693315891134 -124.706043622777 61.998366467024 -2.01144079641367 0.0448909731774194 ARNTL other 1 1 1 0.650526433604874 -2.01144079641367 0.682692223266274 -66.4615911187824 79.2102332552642 -0.83905309184739 0.401897212865112 -41.7149766362087 96.0640754074467 -0.434241171418957 0.664327148269745 LYVE1 other 1 1 1 -0.83905309184739 -0.434241171418957 0.0677743192246975 -125.369901882 53.9059956619943 -2.32571350074126 0.020489610439899 -113.409426867863 65.375765470848 -1.73473191558168 0.0834917745874462 AMPD3 other 1 1 1 -2.32571350074126 -1.73473191558168 6.68560107640438e-15 468.673923067119 163.26992600371 2.87054655158275 0.00429618441216844 -667.111475184675 197.852780768931 -3.3717568820212 0.000813170741101981 SBF2 other 5.36519486381452e-11 1 1 2.87054655158275 -3.3717568820212 0.248554485899107 -241.520988072857 188.753090059331 -1.27956044585517 0.201377143611678 -35.6055567540914 229.497661472573 -0.155145619025606 0.876777988486169 MICAL2 other 1 1 1 -1.27956044585517 -0.155145619025606 8.08894438245844e-12 109.365479485019 29.7864897728884 3.67164712320561 0.000270756630036531 -73.8521729143198 36.3929079148021 -2.02930123328457 0.0430318028078949 RRAS2 other 6.10472632544138e-08 1 1 3.67164712320561 -2.02930123328457 0.0113195829788504 5.48642026411753 69.6298522040856 0.078794081711344 0.937232560965003 -281.421732918509 116.000442824426 -2.42604016041954 0.015669338569335 ZFC3H1 essential 1 1 1 0.078794081711344 -2.42604016041954 0.000125663722575608 25.1583117411508 9.47465205886765 2.6553282996397 0.00821199012716092 2.474637078376 11.1080048658008 0.222779617786708 0.823810883320391 GSC other 0.614495603394723 1 1 2.6553282996397 0.222779617786708 1.5641056769884e-05 -130.513565600984 291.981524441169 -0.446992548075694 0.655101384571244 -1064.04523898552 342.31675992586 -3.10836442602453 0.00200383411357584 UNC79 other 0.0853219646797173 1 1 -0.446992548075694 -3.10836442602453 5.03193095690497e-22 94.1656249328809 77.3051593629136 1.21810272055472 0.22384068931502 -391.501814979487 88.1422546653345 -4.44170411190378 1.13155585745963e-05 COX16 other 4.38029589798578e-18 0.0955598921624655 1 1.21810272055472 -4.44170411190378 2.08500686722898e-05 -26.9280467857903 89.7145890364553 -0.300152372930652 0.764203333358011 -277.027736629325 102.195397440137 -2.71076529441161 0.00697658808997086 TTC9 other 0.112152519388247 1 1 -0.300152372930652 -2.71076529441161 5.27693020199361e-33 20.1942952813015 23.0988424217356 0.874255727304281 0.382458105328896 -163.193678054502 26.3122799429772 -6.20218690315578 1.28958530637974e-09 MED6 other 4.83366806502615e-29 1.20666497117952e-05 1 0.874255727304281 -6.20218690315578 3.01608415945161e-18 -4.36195545377342 126.344091176734 -0.0345244119700998 0.972474739733197 -713.384890026989 143.936542085459 -4.95624585453381 1.02979918434713e-06 EIF2S1 essential 2.53200265185963e-14 0.00907459041246691 1 -0.0345244119700998 -4.95624585453381 1.71549853725731e-05 -245.710002301692 184.428057603022 -1.33228102868479 0.183460605580597 -1249.16776238804 289.24282619975 -4.31875106048567 1.9427147534009e-05 CTIF other 0.0931858805438172 0.161964128991033 1 -1.33228102868479 -4.31875106048567 0.000255512140687255 -897.521280150764 338.377262743397 -2.65242786372259 0.0082817290848672 -2145.15630461103 522.574001033512 -4.10498092206746 4.82413096231895e-05 MRO other 1 0.392973708190502 1 -2.65242786372259 -4.10498092206746 1.49287853077621e-06 118.543536072746 46.9549451386771 2.52462303432874 0.011934451781318 -130.874785536588 73.0303135508036 -1.79206112055845 0.0738132677890348 MBD2 other 0.00891845634285705 1 1 2.52462303432874 -1.79206112055845 3.0679279827521e-19 117.338473456078 22.8476252047684 5.1356967039003 4.23827470729085e-07 -103.272930363184 35.8324637371854 -2.88210520830059 0.00414455064352034 IER3IP1 other 2.60405727175998e-15 1 0.00383436712768603 5.1356967039003 -2.88210520830059 0.844446047593666 -12.0112527108589 23.4039889780091 -0.51321391076303 0.60806045301108 -23.6919429273046 52.1555852312366 -0.454255144914284 0.64987021737434 IRAK2 other 1 1 1 -0.51321391076303 -0.454255144914284 0.000917347402686578 146.765900908979 68.9766325340792 2.12776262796631 0.0339146633286471 -336.67286281021 161.904389528867 -2.07945481768536 0.0381567335197692 CAMK1 other 1 1 1 2.12776262796631 -2.07945481768536 1.03458708572368e-06 141.213122426059 45.2678172693012 3.11950367710404 0.00193146971144497 -297.322206528027 105.432878974576 -2.82001411153462 0.00502064262882362 THUMPD3 other 0.00626442480405691 1 1 3.11950367710404 -2.82001411153462 0.000806100112889397 156.878567631521 70.0926731167604 2.23815929191618 0.0257124801192529 -303.35623862145 156.200910462802 -1.94209007951776 0.0527669208079409 VHL ts 1 1 1 2.23815929191618 -1.94209007951776 0.0665635034681415 -429.537120391996 236.524897758521 -1.8160334259209 0.0700534945342956 -1035.53428579569 491.932226125112 -2.10503445556405 0.0358612037078548 BHLHE40 other 1 1 1 -1.8160334259209 -2.10503445556405 1.38552735456661e-06 190.44702626495 140.708189729819 1.35348927898679 0.176602245034417 -1237.37027222251 303.613833455377 -4.07547396026133 5.45923268211995e-05 ARL8B other 0.00830069438120858 0.442852955173571 1 1.35348927898679 -4.07547396026133 0.0130949258567082 88.4412302229646 36.2055173348073 2.44275560006814 0.0149725177321924 -39.4036386263554 78.1226446830363 -0.504381780548088 0.614248499762854 EDEM1 other 1 1 1 2.44275560006814 -0.504381780548088 0.443881955394815 1.65395319666037 25.0241930704983 0.0660941670327126 0.947333501430321 -57.7780369252473 51.5671179071302 -1.12044340017805 0.263148798158936 CNTN6 other 1 1 1 0.0660941670327126 -1.12044340017805 0.0188085741142287 -938.393284476489 601.246482189192 -1.56074640313855 0.119319243530406 -3476.16330039097 1239.01058208204 -2.80559613506254 0.00525030205941736 CHL1 other 1 1 1 -1.56074640313855 -2.80559613506254 1.63000027025551e-09 131.820296613471 85.5856890359873 1.54021423556038 0.124233562970229 -541.543236208225 134.196360609607 -4.03545397019847 6.43589612651783e-05 MEIS2 other 1.14996519066526e-05 0.519312458448724 1 1.54021423556038 -4.03545397019847 1.14590058384392e-06 11.3306829201466 14.1694246991227 0.799657231027044 0.424344861813224 -80.9935423040863 22.217326844849 -3.64551248085295 0.000299059550696974 DPH6 other 0.00690562209623579 1 1 0.799657231027044 -3.64551248085295 1.84016806677593e-07 9.43006007608397 35.1350296837571 0.268394823085733 0.788522074830014 -246.528936259044 56.3110307507745 -4.37798656803407 1.50045357938129e-05 KATNBL1 other 0.00116795467198269 0.125783023559534 1 0.268394823085733 -4.37798656803407 4.1209090610156e-14 -27.6166844498061 73.4638282267329 -0.375922207110854 0.707157152336052 -793.380752458717 117.740725639905 -6.73837152053206 5.07153159621623e-11 EMC7 essential 3.26829297629147e-10 4.81034771901109e-07 1 -0.375922207110854 -6.73837152053206 0.259865171204222 -125.502891902672 198.736916036153 -0.631502663953191 0.528041337836987 -363.785050746797 264.316679011274 -1.37632272056233 0.169424950706072 GSTM1 other 1 1 1 -0.631502663953191 -1.37632272056233 1.08413367420164e-58 61.739952109356 69.445065629844 0.889047357784098 0.374466745634755 -775.238380697406 86.771035433043 -8.9342990645262 1.1535742265574e-17 PRPF38B essential 1.04770678274846e-54 1.12842630841845e-13 1 0.889047357784098 -8.9342990645262 0.0222080139713778 20.1699205614395 10.1577421505319 1.98566967565556 0.0476930897259847 8.38804657493681 12.9818192748318 0.646137987084674 0.518528385680536 TSPAN2 other 1 1 1 1.98566967565556 0.646137987084674 0.366329916517732 -43.0522536896689 111.683617518652 -0.38548405438675 0.700065960748116 -161.466025498974 148.537289756098 -1.08704033690196 0.277616822633388 GSTM5 other 1 1 1 -0.38548405438675 -1.08704033690196 0.00886626213797621 -292.064319904268 277.126167260402 -1.05390379692954 0.292507985201129 -923.762527146213 368.573034433459 -2.5063215179758 0.0125609294811328 GSTM3 other 1 1 1 -1.05390379692954 -2.5063215179758 2.59624701168896e-16 -144.556714841841 77.3268312475692 -1.86942504315261 0.0622307320362716 -615.580811185187 99.2951854685026 -6.1995031106564 1.30996100491953e-09 SYT6 other 2.12918217428612e-12 1.22559951620271e-05 1 -1.86942504315261 -6.1995031106564 7.53304644460305e-07 25.1098368092321 56.8900877107562 0.441374549058475 0.659159667225017 -184.72120489163 73.399914650213 -2.51664059518213 0.0122041971839948 VAV3 other 0.00460721120551923 1 1 0.441374549058475 -2.51664059518213 5.00238778293924e-13 399.191663342645 162.161714614112 2.46168871791088 0.0142128208942946 -456.386943225634 215.672290405166 -2.11611302670481 0.0348987892353433 PSRC1 other 3.87885148689109e-09 1 1 2.46168871791088 -2.11611302670481 9.08161305948186e-06 84.2257678500238 498.682354973758 0.168896627301874 0.865955920948692 -1728.82352228575 663.238952164313 -2.60663749715569 0.00945543735108112 SORT1 other 0.0507389721633251 1 1 0.168896627301874 -2.60663749715569 1.37867414401184e-42 26.6562593579094 20.6784079117293 1.28908663915027 0.198048344205084 -191.536563924482 26.5530905076763 -7.21334354165328 2.41879598993385e-12 WNT2B other 1.29554009312793e-38 2.31962535434656e-08 1 1.28908663915027 -7.21334354165328 2.37557125089995e-08 424.100585283951 250.384417471973 1.69379783920228 0.0910146413208942 -484.87751606759 314.65352275876 -1.5409886780112 0.124041665431227 PTGFRN other 0.000158996983822733 1 1 1.69379783920228 -1.5409886780112 3.55437465947476e-64 299.776383283129 60.4428047250791 4.95967029734385 1.01195946242208e-06 -501.872017959126 77.9836503433881 -6.43560561411546 3.23169354831544e-10 LAMTOR5 other 3.45414129407757e-60 3.04457849186797e-06 0.00907019266168912 4.95967029734385 -6.43560561411546 1.6384175312508e-41 -116.535902017674 454.610427286057 -0.256342342856878 0.797807689744575 -4647.65866840818 571.972823169884 -8.12566345836288 4.65509224510445e-15 NOTCH2 og 1.5358525937945e-37 4.51869804232289e-11 1 -0.256342342856878 -8.12566345836288 8.53542448881202e-23 85.9769381095883 17.8705713301682 4.81109062050223 2.06877151197003e-06 -18.0154993327445 22.4576204842242 -0.802199829915191 0.422872401390187 TRIM45 other 7.46252163056835e-19 1 0.0183934475129255 4.81109062050223 -0.802199829915191 7.521719097084e-73 87.6412129389483 27.2937218370484 3.21103928083507 0.00141996869103418 -321.878578589056 35.2145151104632 -9.14050861070686 2.33787397512358e-18 CEPT1 other 7.35699344885786e-69 2.28947998383852e-14 1 3.21103928083507 -9.14050861070686 1.6248774767938e-07 18.7456915498145 18.1853336797947 1.03081372494377 0.303197043878378 -45.7791780680879 22.8531765780968 -2.00318664285665 0.0457728881710087 CD101 other 0.00103488446496997 1 1 1.03081372494377 -2.00318664285665 6.05467712327136e-34 116.065012844962 23.9483318502923 4.84647588694348 1.74767984240649e-06 -82.0932297330663 30.7519914416611 -2.66952564320276 0.00787817537305091 AP4B1 other 5.55879906687543e-30 1 0.0155735750756842 4.84647588694348 -2.66952564320276 3.48263693173713e-06 17.0715379526151 65.6227643913517 0.260146583444829 0.794873232534429 -386.986890717573 104.407262846388 -3.70651313105428 0.000237133149014464 NAPG other 0.020230637936461 1 1 0.260146583444829 -3.70651313105428 8.82202557613656e-14 -229.587854798595 279.355484475789 -0.821848388727421 0.411613411551719 -2886.31194797197 438.230862171521 -6.58628179145058 1.3037616511098e-10 SPIRE1 other 6.95175615399561e-10 1.2314028794732e-06 1 -0.821848388727421 -6.58628179145058 5.23166365394612e-12 133.908006456609 46.7248611850451 2.86588345177295 0.00436350968490499 -247.954856235484 70.7190504956722 -3.50619606029153 0.000502584442675995 PPHLN1 other 3.96821688151813e-08 1 1 2.86588345177295 -3.50619606029153 0.00596506249683507 46.0037690352873 19.1435115914928 2.40309980827817 0.0166716749031621 -7.21487649012362 29.2297422916811 -0.24683339381261 0.805152812626831 FKBP11 other 1 1 1 2.40309980827817 -0.24683339381261 1.0607383181907e-11 -1276.00437185974 611.923862134695 -2.08523388417703 0.0376265109435227 -6394.25625845134 934.331024213753 -6.84367327289829 2.61371907450154e-11 ARF3 other 7.99266322756696e-08 2.48616958366586e-07 1 -2.08523388417703 -6.84367327289829 0.0112673651366268 306.615793446911 108.75833522846 2.81923948911895 0.0050320501249408 144.307523414754 166.060343506301 0.869006533214102 0.385319486075787 TMEM106C other 1 1 1 2.81923948911895 0.869006533214102 5.84206977677927e-05 268.244867116365 279.323572153962 0.960337378789176 0.337421385613368 -1221.93866342291 422.809733411586 -2.89004383499707 0.00404548367809364 SLC38A2 other 0.298237662104582 1 1 0.960337378789176 -2.89004383499707 0.00688773304974024 17.2501009669067 8.20314687082793 2.10286384463645 0.0360569573081931 38.9502886465687 12.2968957468389 3.16748953951093 0.00164694413306247 PLEKHA8P1 other 1 1 1 2.10286384463645 3.16748953951093 0.426487798140057 96.607035827616 449.879980131743 0.214739575206982 0.830070537915984 624.320809479042 564.062418057287 1.10682929671027 0.268976630137981 LDHA other 1 1 1 0.214739575206982 1.10682929671027 0.883511489551018 -20.9452739621868 83.7586004290235 -0.250067143611546 0.802652938165946 -50.8418363959212 104.27545779369 -0.487572411300386 0.626097246493576 SAA2 other 1 1 1 -0.250067143611546 -0.487572411300386 0.730057099858874 -16.9680798930397 42.0869522486006 -0.403167228475279 0.687022834909185 12.8951425686917 52.4904282126014 0.245666553080166 0.806055964537944 ANO3 other 1 1 1 -0.403167228475279 0.245666553080166 4.64530601869892e-15 368.595887177667 179.386469745445 2.05475857627789 0.0404949908099801 -1408.14288664661 286.577340804581 -4.91365745349291 1.26523047601513e-06 NARS essential 3.73807775324702e-11 0.011121375884173 1 2.05475857627789 -4.91365745349291 0.933727866258374 -34.2429914263316 167.296821636585 -0.204684052520237 0.83791406072493 -99.1563307733159 269.374062578978 -0.368099028629544 0.712977221162209 GRP other 1 1 1 -0.204684052520237 -0.368099028629544 6.92922278478167e-07 26.3992362662311 39.907539307097 0.661509998476311 0.508633141679403 -233.036662928327 63.4883740498943 -3.67054073152335 0.000271895993628767 KIAA1468 other 0.00424484187795725 1 1 0.661509998476311 -3.67054073152335 1.58987989485581e-64 498.763222331049 35.3055365174057 14.1270540410895 1.3659822159532e-37 -338.298899729065 74.3929860222395 -4.54745692864018 7.04134699970662e-06 FBXO18 other 1.54568123377882e-60 0.0600486072134981 1.34453629516273e-33 14.1270540410895 -4.54745692864018 1.18127844604283e-59 799.968590891542 58.1045552780989 13.7677431151955 4.45724938298398e-36 -462.862441224634 122.187521519437 -3.78813184414255 0.000173042935827174 RBM17 essential 1.14300502439104e-55 1 4.38548766791794e-32 13.7677431151955 -3.78813184414255 1.79975052196893e-45 65.808643486778 8.33797359923738 7.89264234331434 2.40487483442947e-14 -131.066825241359 17.5691071318536 -7.46007319880983 4.70483826951902e-13 ANKRD16 other 1.70238401873041e-41 4.52934780206596e-09 2.32839981469461e-10 7.89264234331434 -7.46007319880983 5.47463301824634e-06 8.92211276943397 5.90138378891591 1.51186790904731 0.131291915168743 58.2405104084554 12.1604021551845 4.78935726509875 2.29662253855769e-06 ECHDC3 other 0.0312437306351319 0.0199875059530675 1 1.51186790904731 4.78935726509875 0.00836563872855567 15.4600881488735 5.80229153283169 2.66447972519032 0.00799605059025702 34.3405701057021 12.2261218912819 2.80878682635983 0.00519582578532182 IL15RA other 1 1 1 2.66447972519032 2.80878682635983 2.00450608517406e-05 36.9023188682069 11.8482337284997 3.11458397207696 0.00196703567544646 -17.027635789273 19.4401351682188 -0.87590110058032 0.381579739429848 TMEM241 other 0.108082968112585 1 1 3.11458397207696 -0.87590110058032 0.00113758665503082 93.7305976749261 46.3227518066327 2.02342464597506 0.0436431954378561 -104.910756781466 79.8354357670837 -1.31408760750726 0.189512447634366 KCTD1 other 1 1 1 2.02342464597506 -1.31408760750726 0.0167922677369971 -95.1878324096823 165.807752083221 -0.574085537097844 0.566214335391789 -700.189637940649 272.051107894922 -2.57374301232801 0.0103991775857554 CABLES1 other 1 1 1 -0.574085537097844 -2.57374301232801 0.604973283555169 -99.4806570510369 105.003181739481 -0.947406120491225 0.343956660403178 -36.819630808595 192.691919103151 -0.191080305702311 0.848551623264073 DOCK2 other 1 1 1 -0.947406120491225 -0.191080305702311 1.12797019840291e-07 4604.03855008263 1201.67092829485 3.83136384651969 0.000146107267630632 -2210.50974557032 1538.49496392112 -1.43680011791293 0.151490339145735 LRP4 other 0.000723592882275467 1 1 3.83136384651969 -1.43680011791293 0.00439662564127252 14.5812670671761 38.9092152202403 0.37475099368211 0.708027042249656 -130.237926191776 51.2640883998796 -2.54052944774655 0.0114127032871202 DDB2 ts 1 1 1 0.37475099368211 -2.54052944774655 1.35562049647677e-09 224.330256690332 62.4697163872524 3.59102409397378 0.000366673263058779 -212.376505162414 82.3057737110468 -2.58033544412097 0.010194998422582 ACP2 other 9.59508187406256e-06 1 1 3.59102409397378 -2.58033544412097 9.76584306949332e-35 190.780792447475 130.278201487551 1.46441070162997 0.14379911964141 -1014.92274285034 167.289904041115 -6.06684993136764 2.82393774612502e-09 PUM1 other 8.9855522082408e-31 2.62795646654395e-05 1 1.46441070162997 -6.06684993136764 9.57730259957112e-06 258.715874909243 278.866187965197 0.927741999835173 0.354053532232651 -636.703272482106 358.239954521105 -1.77730949450697 0.0762127711979652 SPOCD1 other 0.0533647300848103 1 1 0.927741999835173 -1.77730949450697 6.4182462157814e-28 490.564740900496 131.603997300755 3.72758237562804 0.000218789192165443 -504.99327740881 169.133103788072 -2.9857743167865 0.00298791404137582 YARS essential 5.76422692639327e-24 1 1 3.72758237562804 -2.9857743167865 3.70168152584607e-15 148.83869722139 30.9766216511679 4.80487184488624 2.13078697210167e-06 12.8595538674108 39.777000329844 0.323291192417103 0.74662901505794 CDCA8 essential 2.98577631874744e-11 1 0.0189363038210675 4.80487184488624 0.323291192417103 3.93529618385627e-77 232.5521915239 40.229475226827 5.78064193511585 1.41548798313231e-08 -370.230722487527 51.6585658496629 -7.16687961421491 3.27931122415661e-12 GNL2 essential 3.85737731941592e-73 3.14223601498686e-08 0.000131371439714509 5.78064193511585 -7.16687961421491 5.97102890677835e-30 110.848445207962 53.7201678377735 2.06344190030654 0.0396593165647172 -336.985818881657 68.9819295940501 -4.88513181444439 1.45188924107164e-06 AGO4 other 5.40198985196237e-26 0.0127316167549572 1 2.06344190030654 -4.88513181444439 0.0712136464227598 -8.5884095888038 18.1038267556917 -0.474397468817119 0.635452917218666 18.7651245707399 23.2470774554409 0.807203598246193 0.419987309310497 HOOK1 other 1 1 1 -0.474397468817119 0.807203598246193 5.61418012687115e-08 -153.946531860235 84.6412777535225 -1.81881152962425 0.0696229281603468 -492.949805705721 108.687647446969 -4.53547222048616 7.42992430033536e-06 CYP2J2 other 0.000366830529489761 0.0633178148874579 1 -1.81881152962425 -4.53547222048616 4.2825353034851e-56 228.660603742331 63.4785977668277 3.60216847546407 0.000351823343425029 -547.983527281405 81.5427369418615 -6.72020032479542 5.67902794936966e-11 BTF3L4 other 4.12665101843825e-52 5.3831505932075e-07 1 3.60216847546407 -6.72020032479542 2.0628615125595e-52 176.560542680274 59.1170185275157 2.98662799779212 0.00297938398793458 -520.595516500791 75.9399807204857 -6.85535486790497 2.43428619563977e-11 ZCCHC11 other 1.97725275978829e-48 2.31671017239037e-07 1 2.98662799779212 -6.85535486790497 1.34541082254505e-64 259.260240177429 88.2323780199887 2.93837983283976 0.0034740123234161 -947.59284240374 113.340713937424 -8.36056885019192 8.42433783857546e-16 PRPF38A essential 1.30814294276056e-60 8.20168521846419e-12 1 2.93837983283976 -8.36056885019192 0.21092360791782 22.8309506303948 13.3118334010902 1.71508686613558 0.0870381999054145 13.7252512049667 26.8485371628445 0.511210391900269 0.609461924248735 DSC2 other 1 1 1 1.71508686613558 0.511210391900269 6.34187028202002e-24 223.669576343734 23.6686618271666 9.45003050772431 2.07524768302404e-19 -48.2784000874261 55.9311701794802 -0.86317521933661 0.388514612323695 RNF138 other 5.58021166114942e-20 1 2.0281395606194e-15 9.45003050772431 -0.86317521933661 2.06799896527599e-28 417.393792699958 65.0016779522165 6.42127720159454 3.52958613554228e-10 -559.781413958406 116.67014195538 -4.79798348211914 2.20311799187581e-06 ELP2 essential 1.86099226885186e-24 0.0191913608272302 3.34251807035854e-06 6.42127720159454 -4.79798348211914 0.00144247556247224 1062.35250537558 768.959256436024 1.38154589659194 0.167818707202132 -3828.79958354137 1667.11534684863 -2.296661470233 0.0221113738683678 DTNA other 1 1 1 1.38154589659194 -2.296661470233 1.74084118827686e-05 190.523959159023 61.9276164781436 3.07655889236857 0.00222562931136055 -132.984539312272 111.152573796242 -1.19641439483039 0.232183587257583 FHOD3 other 0.0944326665838902 1 1 3.07655889236857 -1.19641439483039 6.81250513319508e-17 477.803570754537 78.151820628471 6.11378681791671 2.1588512281399e-09 -270.177246819917 140.273055927845 -1.9260808501876 0.0547426321324089 TPGS2 other 5.63530424617897e-13 1 2.02867249908307e-05 6.11378681791671 -1.9260808501876 0.00248454977401668 -175.691761690531 98.2052386774617 -1.78902637024854 0.07430145137495 -811.120242226249 237.886849711257 -3.40968928383714 0.000710605920259215 DAGLA other 1 1 1 -1.78902637024854 -3.40968928383714 7.83659342019796e-05 161.026909677449 38.91827327931 4.13756562429648 4.2134793938289e-05 -5.60922590718694 92.8115510743926 -0.0604367219624515 0.951835504534665 TIMM10 essential 0.393553721562341 1 0.356207547954295 4.13756562429648 -0.0604367219624515 3.16466342919862e-49 259.479247355615 33.065508439513 7.84742953008819 3.30029734014517e-14 -1.43470232289277 40.3699805421343 -0.0355388410800784 0.971666302702505 DHX34 other 3.01687364705504e-45 1 3.19369773605848e-10 7.84742953008819 -0.0355388410800784 0.00943793811081169 -1499.64247608545 1636.10801707906 -0.916591362202821 0.359862355025553 -12070.1502023548 3932.67905535874 -3.06919279006707 0.00228004280622318 FADS2 other 1 1 1 -0.916591362202821 -3.06919279006707 1.28134516398563e-07 -6.43670632853841 7.9252314939176 -0.812178967072244 0.417131140818151 -32.3329644132157 9.67598734453561 -3.34156745579823 0.0009046435258177 C5AR2 other 0.000819932770434404 1 1 -0.812178967072244 -3.34156745579823 0.00126049171244752 245.577184546505 96.9639263928224 2.53266543221051 0.0116804791815383 -173.843027690269 174.574479287534 -0.995810088620916 0.319911724707546 TMEM165 other 1 1 1 2.53266543221051 -0.995810088620916 0.000929964584554328 29.1156524622788 58.9649617927886 0.493778874386376 0.621718641179193 -313.436760072956 106.160898017712 -2.95246899683027 0.00332803571676786 CLOCK other 1 1 1 0.493778874386376 -2.95246899683027 0.675905066209128 1811.19426521775 2404.21735292518 0.75334048438428 0.451671470909167 0.566155870613409 4144.48103202859 0.000136604768181625 0.999891070646838 PDGFRA other 1 1 1 0.75334048438428 0.000136604768181625 0.00111417907190004 17.6889242306738 13.1263126020724 1.34759279067306 0.178489218802552 -27.8325444484378 17.2464820348185 -1.61380995801041 0.107292124003016 GGACT other 1 1 1 1.34759279067306 -1.61380995801041 0.894215274540934 127.142067123043 1008.12691989775 0.126117123363731 0.899697348640038 -393.499137693952 1430.24279666884 -0.275127508847061 0.783348608768772 COL4A2 other 1 1 1 0.126117123363731 -0.275127508847061 0.294023580050242 -71.5093860912147 69.476961934234 -1.02925320999074 0.303931337552445 -144.059851522512 91.9812563941224 -1.56618703820746 0.118030305094483 CLDN10 other 1 1 1 -1.02925320999074 -1.56618703820746 1.37000125499462e-10 195.277504793612 90.8826611110443 2.14867723288839 0.0322100491552984 -405.571489081656 120.320479202129 -3.37076025437306 0.000816355383577152 DZIP1 other 1.00421091991105e-06 1 1 2.14867723288839 -3.37076025437306 1.70592898805956e-25 234.493967773309 51.1155306190826 4.58752877908632 5.86747899138329e-06 -308.704659062232 67.6642475004071 -4.56230092650294 6.58238187119758e-06 UBAC2 other 1.51332960530764e-21 0.0562201235618985 0.0513873810065348 4.58752877908632 -4.56230092650294 6.45368791797205e-13 1016.69018254339 190.064049915132 5.3491977204388 1.42646149930118e-07 -209.489241805255 264.338018504534 -0.792505153024977 0.428495220550265 ARGLU1 other 4.99128223575958e-09 1 0.00130193141041218 5.3491977204388 -0.792505153024977 3.0274732560654e-15 260.060571145832 69.660790148464 3.73324176472273 0.000214019133807526 -294.523971159959 93.2199214962183 -3.15945311294761 0.00169041743774412 BIVM other 2.4440791596216e-11 1 1 3.73324176472273 -3.15945311294761 9.88848617599796e-19 313.290655262601 70.678217157654 4.43263381366537 1.17870995302971e-05 -312.592551070898 94.5814401600561 -3.30500942406788 0.00102797212682999 ERCC5 other 8.35181542424788e-15 1 0.102158791629085 4.43263381366537 -3.30500942406788 1.96394338892826e-13 339.180554181106 108.625287546464 3.12248245175898 0.00191245769744175 -479.436526472037 145.362129197852 -3.29822168344464 0.00105252291940117 TPP2 other 1.53619651881969e-09 1 1 3.12248245175898 -3.29822168344464 5.68432617791225e-08 44.7499681911365 11.5330942718658 3.8801354724292 0.000120487835512869 -10.5310412101501 15.4335622714081 -0.682346759934978 0.495381230318695 KDELC1 other 0.000371243342679449 1 0.99703683886899 3.8801354724292 -0.682346759934978 1.16695332499422e-09 160.776959891093 40.1890626616395 4.00051529553475 7.4219862921967e-05 -76.5422669048028 55.0157761999617 -1.3912785057617 0.164848858905629 CARS2 other 8.29353728073395e-06 1 0.621220252656864 4.00051529553475 -1.3912785057617 0.75777620157876 -21.4745618925271 42.2562407708334 -0.508198587966906 0.611571098215592 -62.552479983195 88.1491399426921 -0.709620990333676 0.478318517337866 OSTF1 other 1 1 1 -0.508198587966906 -0.709620990333676 8.01527784435497e-05 102.969241583246 38.9425592963319 2.6441313422599 0.00848551746310634 -165.798224139743 81.2365947968648 -2.0409302550695 0.041859475310938 RFK other 0.401966183894402 1 1 2.6441313422599 -2.0409302550695 1.04828129748878e-06 394.620443125485 141.036882851028 2.79799464614025 0.0053689008080499 -907.46539417035 303.055884612564 -2.99438301727907 0.00290582183307308 UBQLN1 other 0.00634524669369957 1 1 2.79799464614025 -2.99438301727907 6.41097160649304e-07 105.962145482751 31.6947400116142 3.34320917110922 0.00089927525156789 -172.516872941468 68.1047203938185 -2.53311183048519 0.0116534271627298 NAA35 essential 0.00394082424651127 1 1 3.34320917110922 -2.53311183048519 0.000102262329893547 39.0462466975299 11.6587481138487 3.34909428664551 0.000881189183146965 -25.6698095676695 24.3208719066559 -1.05546419824877 0.291797572370262 C9orf40 other 0.506403057632843 1 1 3.34909428664551 -1.05546419824877 0.651325543990588 568.24524323145 726.159466034312 0.782535062628516 0.434324984328328 -173.358735083338 1514.81369910101 -0.114442281045002 0.908939880582332 ANXA1 other 1 1 1 0.782535062628516 -0.114442281045002 0.792316344166535 73.1259063163945 147.786411012915 0.49480805315723 0.620983724662365 200.536595510292 317.559071200846 0.631493834365887 0.528047103884345 CTSL other 1 1 1 0.49480805315723 0.631493834365887 0.463860572498551 -2.62719462822057 73.4383745276321 -0.0357741391352835 0.971478788901643 176.871714229289 158.695958969799 1.11453193501259 0.265663631080891 TMEM2 other 1 1 1 -0.0357741391352835 1.11453193501259 0.000254962101040529 91.8316359221665 50.1339046089579 1.83172718419698 0.0676710255246744 -280.453293090075 107.726252191761 -2.60338856484905 0.00954411472769839 AGTPBP1 other 1 1 1 1.83172718419698 -2.60338856484905 3.09740488957633e-08 1996.42854011398 634.856602593798 3.14469209575405 0.00177578657610479 -4600.92108724246 1364.1611003585 -3.37271095476432 0.000810430237432014 GOLM1 other 0.000205915477059034 1 1 3.14469209575405 -3.37271095476432 0.00168184512067301 -280.224113755306 157.158190654684 -1.78307037379317 0.0752688413929666 -1217.60100720845 339.609501658012 -3.5852972348064 0.000374667542152464 FAM189A2 other 1 1 1 -1.78307037379317 -3.5852972348064 9.98499775679327e-06 915.175097559201 521.596224936767 1.75456618320071 0.0800359693163441 -3647.61357668599 1088.08208649896 -3.35233308400714 0.000871201990088561 PSAT1 other 0.0555066025300138 1 1 1.75456618320071 -3.35233308400714 2.89943469011634e-09 90.7209725828749 41.7405327049087 2.17345028210927 0.0302815296924483 -413.953472948213 89.6908227647603 -4.61533811585076 5.1627575020446e-06 ISCA1 other 2.02844450920539e-05 0.0443222731550529 1 2.17345028210927 -4.61533811585076 0.463825993937622 75.4310805883097 91.0484040630932 0.828472298493433 0.407855318515628 -63.8347818159696 167.076548064309 -0.382069072862333 0.702595859185969 ADAM19 other 1 1 1 0.828472298493433 -0.382069072862333 0.518027407089545 -109.325817430418 121.865429496057 -0.897102795128256 0.370158014159613 37.6110976054398 223.626712605157 0.168186962851112 0.866514007045444 HAVCR2 other 1 1 1 -0.897102795128256 0.168186962851112 0.112767426083396 28.9151042539255 14.3438790857231 2.01584969317718 0.0444286271171866 13.7319859268625 26.3225317806946 0.52168180634257 0.602156795279328 CCNJL other 1 1 1 2.01584969317718 0.52168180634257 0.000742979448606716 194.985089601737 164.085012798077 1.18831748419148 0.235355225965043 -879.423675173187 322.496315841512 -2.72692626853254 0.00665060819164492 TAOK3 other 1 1 1 1.18831748419148 -2.72692626853254 5.18212730399282e-12 -12.2499437317125 34.4092726463272 -0.356007052448406 0.722006691122348 -360.539367339837 57.5571887391031 -6.26401975562255 8.97316819885682e-10 USP30 other 3.93116177280895e-08 8.40696128550895e-06 1 -0.356007052448406 -6.26401975562255 0.0176223360715702 -113.625836696375 68.0254911781422 -1.67034202515079 0.0955693802152556 -357.217242346286 125.5661286872 -2.84485351329223 0.00465244342642835 SDS other 1 1 1 -1.67034202515079 -2.84485351329223 0.000138354446583108 120.431635243911 74.6361912813207 1.6135822739129 0.107339895170073 -395.531263693055 140.062210786271 -2.82396844568318 0.00496022942184606 MSI1 other 0.673647800413152 1 1 1.6135822739129 -2.82396844568318 1.10008107154056e-05 8.3399359743898 2.81808257987132 2.95943633233438 0.00324958463375011 -12.0787314925969 5.43828360330555 -2.22105582821299 0.0268590451474543 HNF1A other 0.0608454840669082 1 1 2.95943633233438 -2.22105582821299 4.0403435930786e-06 315.586884423508 157.810552887016 1.99978314916273 0.0461436097084443 -1012.55041201008 310.164353459899 -3.26456087140584 0.00118271934897904 FBXO21 other 0.0233451052808082 1 1 1.99978314916273 -3.26456087140584 0.0336894943903386 -12.9159597330618 21.8011610506958 -0.592443664033645 0.553860654165334 -109.075651321495 43.2286711408743 -2.52322471273838 0.011982945965534 TBX3 other 1 1 1 -0.592443664033645 -2.52322471273838 0.960013599275167 11.1429571828738 51.2731848817207 0.217325239471253 0.828056318782945 -7.53546418567309 98.9460431795607 -0.0761573069879938 0.939328800858373 OASL other 1 1 1 0.217325239471253 -0.0761573069879938 0.000746658200479587 -17.384270226583 41.1308867512107 -0.422657316671425 0.672753667823777 -290.404714348975 80.8395551693882 -3.59235913335336 0.000365029626316173 HRK other 1 1 1 -0.422657316671425 -3.59235913335336 2.6891472343194e-05 82.2293693040878 45.5238098460361 1.80629366439654 0.0715618943832262 -270.551065404472 89.4735034483799 -3.02381213406449 0.00264347852460168 RNFT2 other 0.143116415810478 1 1 1.80629366439654 -3.02381213406449 0.000144467727316151 100.521108443378 30.7054559509856 3.27372140650956 0.00114573918130751 227.409913965587 59.2548205730332 3.83782976247981 0.000142436760011137 P2RX4 other 0.701679751574545 1 1 3.27372140650956 3.83782976247981 0.0765024259017652 -28.4349846037496 33.7212638049104 -0.84323602959415 0.399557758065484 -143.472901998212 63.2812939398323 -2.26722453138562 0.023864240041025 BICDL1 other 1 1 1 -0.84323602959415 -2.26722453138562 5.61394805626004e-06 54.6865319865277 113.333545838662 0.482527318649131 0.629673006074741 -786.150033670037 200.781865534872 -3.91544341704255 0.000104659694747376 DTX1 other 0.0319900365959946 0.831207295683657 1 0.482527318649131 -3.91544341704255 1.53127374804574e-05 214.618761102516 71.6037945326112 2.9973098842516 0.00287862780807457 -176.915807799254 123.98390745002 -1.42692556992182 0.154313806623461 TRAFD1 other 0.0835769211683363 1 1 2.9973098842516 -1.42692556992182 1.32321354979846e-14 29.6540991791362 19.7507348464202 1.50141751229631 0.1339714488482 -128.862553047767 27.6529056853532 -4.66000045398563 4.20744891947621e-06 MTO1 other 1.05685066222403e-10 0.0362345500945291 1 1.50141751229631 -4.66000045398563 3.47549885557773e-07 -251.037767480425 232.126361858443 -1.08147030552917 0.280095505587703 -1589.29445449066 336.400814354347 -4.7244072745216 3.13266496764787e-06 ADGRB3 other 0.00216905883576606 0.0271100826300247 1 -1.08147030552917 -4.7244072745216 4.43137992504673e-15 171.207248396691 114.267160017411 1.4983066733312 0.134773924652518 -755.718917053731 160.414690681065 -4.71103309706369 3.31460354628485e-06 ANKRD6 other 3.56814711564763e-11 0.0286547476576326 1 1.4983066733312 -4.71103309706369 1.09079825438882e-05 37.7889322897553 23.6187786114254 1.59995285579565 0.110333370117366 -68.4764240297199 33.0685345342157 -2.07074262570868 0.038970798861215 KHDC1 other 0.0603647753978771 1 1 1.59995285579565 -2.07074262570868 1.98071853120887e-05 29.7881135885919 20.1111491568426 1.48117411671907 0.139282477988209 -55.7671557515555 27.7464500907797 -2.00988434805529 0.0450589769600092 CEP162 other 0.106839957573406 1 1 1.48117411671907 -2.00988434805529 6.13300122843093e-13 198.888760664387 224.018995760834 0.887820963525448 0.375126563912587 -1440.65552487325 309.068956566798 -4.66127540234502 4.18269831555845e-06 SYNCRIP other 4.74448975031417e-09 0.0360297632902205 1 0.887820963525448 -4.66127540234502 3.85408622602888e-19 -13.8395911470137 69.8656591428615 -0.198088607719487 0.843068062980681 -656.43838354696 96.3905149998488 -6.810196869972 3.24370057389674e-11 SNX14 other 3.26787971104989e-15 3.0818399152593e-07 1 -0.198088607719487 -6.810196869972 0.162318521484228 -271.682307766284 266.068619351434 -1.02109864901969 0.307773934759027 -680.230185879728 367.082935439591 -1.85306948432548 0.064547839569001 NT5E other 1 1 1 -1.02109864901969 -1.85306948432548 0.882932658382983 -6.89510090810494 45.0155329340117 -0.153171593418931 0.878333821837829 13.438589622057 62.1059109115324 0.216381813338182 0.828791343674291 MRAP2 other 1 1 1 -0.153171593418931 0.216381813338182 0.648943421047118 27.3639547705006 29.7193962966039 0.920743964561204 0.357692112798892 31.4685696062951 41.7250627753919 0.754188670145136 0.451142133516809 EPHA7 other 1 1 1 0.920743964561204 0.754188670145136 1.67512058235104e-22 101.663727917744 65.7116445463307 1.54711891050093 0.122556776477941 -582.026981712394 92.8608128475667 -6.26773516044713 8.77894579174176e-10 AKIRIN2 essential 1.46221275633422e-18 8.22587220686203e-06 1 1.54711891050093 -6.26773516044713 4.04133034330957e-12 5.01222504746709 58.9768639426809 0.0849862931392627 0.932311119529413 -431.58297154151 83.3435163999941 -5.17836287912542 3.41934475835065e-07 ORC3 essential 3.07545239125858e-08 0.003062023231103 1 0.0849862931392627 -5.17836287912542 0.371130782868393 31.540644247787 35.8845720392741 0.878947203641363 0.379912936099731 -6.73144424778819 49.8597396521534 -0.135007609240444 0.892668019025525 LCA5 other 1 1 1 0.878947203641363 -0.135007609240444 8.42156700701193e-17 71.9753848891123 67.768296549711 1.06208047942175 0.288784393148944 -518.031303325773 95.13696084989 -5.44511090850525 8.64335310060177e-08 MAP3K7 other 6.95789866119326e-13 0.000785680796844701 1 1.06208047942175 -5.44511090850525 0.298428818893733 -110.030328893225 71.499462286933 -1.53889729200569 0.124556437306043 -105.229038830832 89.8326698612748 -1.17138941760646 0.242083504312839 PRR5L other 1 1 1 -1.53889729200569 -1.17138941760646 0.738009902292177 -135.784766450317 176.955280632422 -0.76733944285265 0.443295051548609 -133.172791336405 222.296663885578 -0.599076877757162 0.549432761989818 LMO2 other 1 1 1 -0.76733944285265 -0.599076877757162 9.40047723033156e-10 376.845358160579 110.132012762743 3.42176038289989 0.000681138988655165 -417.727648743237 147.270889910347 -2.83645769369312 0.00477521109033637 PHF21A other 6.70066016978033e-06 1 1 3.42176038289989 -2.83645769369312 1.10366696931011e-26 308.60554411303 63.2804618656128 4.8767903238192 1.51244441318468e-06 -394.295066681023 79.3317065106857 -4.97020780244924 9.62033439445795e-07 NAT10 essential 9.85353870200067e-23 0.0084870590027908 0.01349705394326 4.8767903238192 -4.97020780244924 0.118970847875071 -40.7567658429991 19.7040426955568 -2.06844689045408 0.0391897588442834 -32.6057232396116 24.7599230107444 -1.316874984848 0.188575445330573 PRRG4 other 1 1 1 -2.06844689045408 -1.316874984848 4.17557323367227e-12 1266.08258219459 342.005272084863 3.70193878730745 0.000241382438823671 -1112.06142481148 429.637537484228 -2.58837119150072 0.00996522782255859 CAPRIN1 other 3.17468832956103e-08 1 1 3.70193878730745 -2.58837119150072 0.000722482991881762 309.774715909078 405.298370750667 0.764312758857959 0.445093379167386 -1575.81103811554 619.302772050999 -2.54449214379711 0.0112867136007433 ATP5G2 other 1 1 1 0.764312758857959 -2.54449214379711 4.26332559994125e-09 70.6512924302589 50.5572660641022 1.397450810348 0.162987102238533 -335.541510438297 79.5746713546171 -4.21668735448479 3.01492311838049e-05 DNAJC14 other 2.95704263611925e-05 0.249153246502964 1 1.397450810348 -4.21668735448479 0.179439318860243 2128.39733545998 1181.33136789499 1.80169374428156 0.0722842802032645 2634.32280574188 1859.47478101668 1.41670262626609 0.157283979286474 CD63 other 1 1 1 1.80169374428156 1.41670262626609 0.223076409559252 28.4469030586428 35.5494088650413 0.800207484929994 0.424024389459137 -40.128429255235 54.2794907183345 -0.73929266329097 0.460125315590572 PRPH other 1 1 1 0.800207484929994 -0.73929266329097 3.1350101308954e-08 129.9216654593 21.6871129792506 5.99073125056361 4.5099462856023e-09 109.06498577663 36.8025392854735 2.96351794996059 0.00321531016968791 AVIL other 0.00020829007309669 1 4.22040773406663e-05 5.99073125056361 2.96351794996059 2.44093188956187e-08 -67.4392972744746 144.712205469796 -0.46602356073241 0.641431362756829 -1176.73610264108 227.784264338869 -5.16601138387011 3.64591520538287e-07 GDF11 other 0.000163200706136106 0.0032634587003382 1 -0.46602356073241 -5.16601138387011 0.333304708412322 -33.1731811515661 32.5818166517785 -1.01815013895965 0.309171240955005 -77.3687063095487 52.5425854408608 -1.47249522764027 0.141608677335003 GLS2 other 1 1 1 -1.01815013895965 -1.47249522764027 0.141239294374984 876.240148707611 506.628197048924 1.72955266566617 0.0844179779485312 175.598401510532 797.45817419805 0.22019763191608 0.825820305804574 ITGA7 other 1 1 1 1.72955266566617 0.22019763191608 0.343466809737934 -200.895323027185 152.693474070436 -1.31567720395512 0.188975386548848 -307.57092061692 238.121245558409 -1.2916567771836 0.197161896298294 TESPA1 other 1 1 1 -1.31567720395512 -1.2916567771836 0.00978471778018755 100.642433269223 36.8347527994254 2.73226845900789 0.00654553223677629 27.6345698268986 57.9797470523136 0.476624532389986 0.633868288976918 RDH5 other 1 1 1 2.73226845900789 0.476624532389986 0.0816390685937913 -546.766527765325 474.880847262066 -1.15137624715277 0.250237209400667 -1865.58681197045 831.097180839314 -2.24472763833277 0.0253091803572525 AGAP2 other 1 1 1 -1.15137624715277 -2.24472763833277 0.00216210330309693 546.565382089415 156.14953942069 3.50026893526012 0.000512649507952174 589.926531641412 245.787201213091 2.40015154869663 0.0168066786871834 BLOC1S1 other 1 1 1 3.50026893526012 2.40015154869663 1.08542036544941e-06 929.459908520448 232.708765252818 3.99409067170577 7.6759382356034e-05 -353.134623053849 407.267633287985 -0.86708246418429 0.386395487984492 CDK4 essential 0.00655919526841078 1 0.642092233408225 3.99409067170577 -0.86708246418429 0.0171501299621834 -144.406827715125 120.915079879311 -1.19428302788422 0.233019586018252 -517.270497008297 184.796642879901 -2.79913362573621 0.00535244347875847 PPP1R1A other 1 1 1 -1.19428302788422 -2.79913362573621 0.014832482769525 116.679974891533 42.5542878682887 2.74190876493276 0.00635854237897342 56.7159729116151 64.9750627961511 0.872888312390748 0.383202233095862 TROAP other 1 1 1 2.74190876493276 0.872888312390748 2.16117786584756e-08 646.820105152638 144.61546357279 4.47268977447265 9.97297002260787e-06 -278.599703749537 253.094023004024 -1.10077551592401 0.271629374721226 TSPAN31 other 0.000145101481913005 1 0.0866252176163719 4.47268977447265 -1.10077551592401 0.00598636783157133 123.553571428569 146.755973451516 0.841898074216297 0.400326415204193 -542.375000000003 252.4306625273 -2.14860981851342 0.0322391686039324 B4GALNT1 other 1 1 1 0.841898074216297 -2.14860981851342 2.36535619423885e-13 -78.5967901949351 78.8022403569011 -0.997392838566067 0.319127079056105 -823.525909710406 121.677327629522 -6.76811305568644 4.22269899352742e-11 TFCP2 other 1.84805279455881e-09 4.00860815455558e-07 1 -0.997392838566067 -6.76811305568644 2.52760453086587e-06 37.5600969202322 28.721325423062 1.3077424654669 0.191649789612059 -150.835524218312 46.3170212743072 -3.25658947981577 0.00121561455244683 COQ10A other 0.0148597870369605 1 1 1.3077424654669 -3.25658947981577 0.00150770685825164 -1450.75596590921 1252.94859201366 -1.15787349549405 0.247548092430408 -6599.61565459294 1914.52666052983 -3.44712653558271 0.000621443750920687 FAIM2 other 1 1 1 -1.15787349549405 -3.44712653558271 0.00280172972508301 231.766179940064 118.757306490094 1.95159512109173 0.0516262041807564 -220.324139111408 191.512216451003 -1.15044430686633 0.250591500081032 PAN2 other 1 1 1 1.95159512109173 -1.15044430686633 0.0754911704396602 77.5948467095162 44.8994777843031 1.72819040529339 0.0846588799695111 -13.2923999892221 70.0063072562969 -0.18987432004602 0.849495578539778 ESPL1 essential 1 1 1 1.72819040529339 -0.18987432004602 8.88377620978635e-06 44.3649672531145 20.6765529208923 2.14566554796891 0.0324512336480443 -73.4013098754328 32.927566179553 -2.22917507705178 0.0263110708021602 ZC3H10 other 0.0496780765651253 1 1 2.14566554796891 -2.22917507705178 0.0012016454497176 254.089460053576 490.087838931566 0.518456978258252 0.604402479710376 -1956.88852498896 748.911397256166 -2.61297735908218 0.00928594239026286 HNRNPA1 other 1 1 1 0.518456978258252 -2.61297735908218 0.0145848512652611 82.3007668428812 64.8637598473625 1.26882510413444 0.205209549750758 -169.404851549054 111.570258349251 -1.51836926843677 0.129677285078917 SLC26A10 other 1 1 1 1.26882510413444 -1.51836926843677 3.43528166562476e-07 -100.79857618344 95.0978772167059 -1.05994559640636 0.289754830571214 -737.466555719931 146.868588527215 -5.021268081318 7.49020658866852e-07 ACVR1B other 0.00214464634384954 0.00663482499624258 1 -1.05994559640636 -5.021268081318 7.91532294043351e-07 1886.99191822184 413.816295139298 4.55997489800792 6.73401550691764e-06 -11.1032644524082 724.227052445947 -0.0153311926348359 0.987775289583299 OS9 other 0.0048330961874287 1 0.0588620295459671 4.55997489800792 -0.0153311926348359 0.0013032153520142 -0.906778039915877 1.90528510536188 -0.475927742973484 0.634364235656597 -9.90276095134865 3.07252988707159 -3.22299906439215 0.00136376201142091 MIP other 1 1 1 -0.475927742973484 -3.22299906439215 0.475803949762822 -109.597116050842 142.186552583012 -0.770798040038676 0.441242228442103 -262.272356569248 215.085971289131 -1.2193838352046 0.223354781068127 KCNH3 other 1 1 1 -0.770798040038676 -1.2193838352046 2.42525749267818e-16 29.6645465201141 28.5398329963922 1.03940855308663 0.299189507858049 -161.258137426188 36.235929097555 -4.45022775577373 1.09001148644857e-05 LTV1 essential 1.98968124699318e-12 0.0921713712940907 1 1.03940855308663 -4.45022775577373 0.0220938654926189 -362.563540966505 201.1408602237 -1.80253549956621 0.0721484888541256 -694.331582887293 256.152247103483 -2.71062069819278 0.00697957970324299 MAP7 other 1 1 1 -1.80253549956621 -2.71062069819278 0.662376214824186 -152.224564919084 288.272079237542 -0.528058649737106 0.597726052106966 -351.183988828627 395.342388559479 -0.888303402294519 0.374865124794168 CD164 other 1 1 1 -0.528058649737106 -0.888303402294519 5.29620837766899e-14 -18.6968270904677 19.7706404146687 -0.945686467323319 0.344831116816722 -155.729946088615 26.1885003787728 -5.94650109155704 5.61306566784902e-09 AFG1L other 4.1903600684117e-10 5.20331187409604e-05 1 -0.945686467323319 -5.94650109155704 4.25775568246877e-06 49.6437152065555 153.530569469664 0.32334743092557 0.746586810468118 -545.512159390571 195.53932566964 -2.78978234952188 0.00550502822852605 NHSL1 other 0.0245672502878448 1 1 0.32334743092557 -2.78978234952188 4.14194284409503e-09 132.483900916961 45.8510615848855 2.88944020787152 0.0040508695898471 -65.6601556967798 58.3911814038506 -1.12448753592867 0.261422122571609 AHI1 other 2.87533672237077e-05 1 1 2.88944020787152 -1.12448753592867 0.00129664868571457 60.6081274249483 133.515275790622 0.453941521418073 0.650096276188544 -338.250791300804 173.7462914564 -1.94680869712655 0.0521980141143917 HEY2 other 1 1 1 0.453941521418073 -1.94680869712655 0.390202163802229 68.9985532494315 50.5432815591408 1.36513797919306 0.172913661833633 75.9158682005223 65.5184623167565 1.15869429037419 0.24721505724326 PKIB other 1 1 1 1.36513797919306 1.15869429037419 0.0014070204126167 31.6499531702645 12.6226272406594 2.50739822755084 0.0125232793925395 1.0032550901625 17.3109363085635 0.0579549870832928 0.953810913444968 SMPD2 other 1 1 1 2.50739822755084 0.0579549870832928 9.42187507873134e-05 160.379190172277 346.260459403745 0.463175005452391 0.643468982493203 -1224.92562179485 474.868871957516 -2.57950287780589 0.010219229882116 MICAL1 other 0.468455628914522 1 1 0.463175005452391 -2.57950287780589 8.12565206768713e-16 113.783074221778 90.9049449665268 1.2516708993518 0.211357847709749 -480.647980341642 115.407367768548 -4.16479458491413 3.7547134590156e-05 REPS1 other 6.6150933483041e-12 0.30822442785059 1 1.2516708993518 -4.16479458491413 0.871923129181222 -1.27563305836273 11.3521461464179 -0.112369330160997 0.910582169726306 3.13966428555656 14.4133836704189 0.217829786353374 0.827663411189969 STX11 other 1 1 1 -0.112369330160997 0.217829786353374 0.341752656104579 270.210328787892 213.89854282636 1.26326399992002 0.207169418819147 460.876312234625 348.173906914109 1.32369572527535 0.186297735885211 KCNMB4 other 1 1 1 1.26326399992002 1.32369572527535 0.438592756461336 364.004483045851 292.988921669251 1.24238309411838 0.214763049843246 200.188734046502 476.913475857318 0.41975902166873 0.674868264429815 GNS other 1 1 1 1.24238309411838 0.41975902166873 1.30577050163838e-05 -40.3258275163223 260.055550452965 -0.155066205839801 0.876841048494456 1651.05614351123 423.330187586662 3.90016160416917 0.000111325310505136 CPM other 0.0717520890650291 0.880917182027144 1 -0.155066205839801 3.90016160416917 0.000317060814549373 203.153681603243 127.269984298523 1.59624190042114 0.111160980265859 -456.117128274415 207.175836983299 -2.2015942347137 0.0282183133900344 MDM2 og 1 1 1 1.59624190042114 -2.2015942347137 0.000239423489389553 37.749247782939 58.5929920411137 0.644262162895709 0.519742686207351 -464.260333086996 131.206157434289 -3.53840354877786 0.000445583609412709 KLHL36 other 1 1 1 0.644262162895709 -3.53840354877786 0.713339273326376 8.03564659649403 16.0182719160415 0.501655024874859 0.61616226167919 -15.982010729315 36.9697025059779 -0.432300225481414 0.665735975073605 BCO1 other 1 1 1 0.501655024874859 -0.432300225481414 1.32614120804297e-09 85.5980790028802 16.4562584139135 5.20155170451797 3.04087411611472e-07 -71.4273237033619 37.9805625171474 -1.88062837855848 0.0606857381150325 MPHOSPH6 other 9.3983627414005e-06 1 0.00275959326037411 5.20155170451797 -1.88062837855848 0.145401997194223 6.90153015879818 4.1653455003629 1.6568926054746 0.0982572844890366 -3.92643316307765 9.61349543759557 -0.408429294897516 0.683158129042929 CHST5 other 1 1 1 1.6568926054746 -0.408429294897516 0.403935286712585 -378.447014885985 377.566455059472 -1.00233219825203 0.316736591389116 -1022.87741501268 845.477283523579 -1.20982246944563 0.226999568563117 KIAA0513 other 1 1 1 -1.00233219825203 -1.20982246944563 0.000766916098231939 304.999539560333 410.845405845945 0.742370573506422 0.458260767949373 -3074.4030560344 948.219165568135 -3.24229162167625 0.00127632564320333 DYNC1LI2 other 1 1 1 0.742370573506422 -3.24229162167625 0.585013612090704 4.59337823512423 10.7078826165416 0.428971665044997 0.668154751290352 25.550778642738 24.7134795112346 1.03388026081567 0.301762641351569 FBXL8 other 1 1 1 0.428971665044997 1.03388026081567 0.247564919157081 27.7593061697657 33.1264663833347 0.837979694197958 0.402500191791577 126.258561962418 76.4562008910347 1.65138419763181 0.0993785231515108 FHOD1 other 1 1 1 0.837979694197958 1.65138419763181 0.0816001849671125 32.0114573928207 14.2893862683074 2.24022619248661 0.0255769760720785 30.8975061490085 33.4582782653759 0.923463721113905 0.356274034498235 CCDC102A other 1 1 1 2.24022619248661 0.923463721113905 0.128807348780244 30.7334910963817 16.1937489940354 1.8978613974875 0.0583715758999533 50.1784114474575 37.374698463348 1.3425770243114 0.180104364217963 SLC9A5 other 1 1 1 1.8978613974875 1.3425770243114 0.204522925950233 4.0188168471401 2.35339556402125 1.7076673843445 0.0884099372961445 0.449528333222625 4.6505739449768 0.0966608290807143 0.923040162854077 ZNF670-ZNF695 other 1 1 1 1.7076673843445 0.0966608290807143 0.176260246594445 17.0166025074902 65.4384042508118 0.26003999795394 0.794955114343497 -250.93556756574 146.831185270069 -1.70900730048722 0.0881579710689554 PCNX2 other 1 1 1 0.26003999795394 -1.70900730048722 0.884010317638201 -39.6782646175176 81.990701718138 -0.483936151125048 0.628673047172115 -43.8916209946286 183.971355234408 -0.238578559899741 0.811543972702199 KCNK1 other 1 1 1 -0.483936151125048 -0.238578559899741 0.000183190000650438 150.914756328941 64.0305039473856 2.35691970272402 0.0188665025042344 -387.216542503518 143.672127944926 -2.69514030342718 0.0073066270603764 NTPCR other 0.877296913114949 1 1 2.35691970272402 -2.69514030342718 0.809953760405281 1.8347509113002 6.22807351812735 0.29459365018091 0.768444203703672 -2.99122632346777 10.7570652064773 -0.278070855391545 0.781089483485238 GPR55 other 1 1 1 0.29459365018091 -0.278070855391545 0.164965776946821 56.9399797032813 51.7775529265302 1.09970395441585 0.272065187998101 -60.7702877889815 95.3889348400885 -0.63707900597546 0.524406222116202 SP110 other 1 1 1 1.09970395441585 -0.63707900597546 0.593286368892385 -150.218962684816 187.180505679325 -0.802535296822895 0.422678613097983 -413.818373834567 448.417928637188 -0.922840830856664 0.356598229521039 DOCK10 other 1 1 1 -0.802535296822895 -0.922840830856664 0.00010895601934407 4268.56014580804 2803.1484021848 1.5227735151236 0.128538656006479 -10974.0978839957 4841.56939669541 -2.26664062514233 0.0239002224670357 ITM2C other 0.537588999443643 1 1 1.5227735151236 -2.26664062514233 0.000972979186641492 17.6049742218828 10.2749062548185 1.71339511867826 0.0873474617853783 -39.4786561432541 20.524156460097 -1.92352149624314 0.0550624260251581 SLC19A3 other 1 1 1 1.71339511867826 -1.92352149624314 0.00542008550054522 593.045560966468 749.476295796788 0.791279943465036 0.429208923625951 -4691.58149466195 1864.57398680822 -2.51616805117666 0.012220334191842 SERPINE2 other 1 1 1 0.791279943465036 -2.51616805117666 6.39704599589159e-21 57.1981725765469 47.0386542439564 1.21598233401619 0.224651101011663 -489.620467656106 73.609992718063 -6.65154892123714 8.73043020002369e-11 EIF4E2 other 5.51809187605608e-17 8.26073305526241e-07 1 1.21598233401619 -6.65154892123714 0.00769759104945135 17.3736639172241 26.5965697092999 0.653229499409808 0.513951078735596 -95.6166542842319 46.6535738412498 -2.04950331585724 0.0410079925874116 ARMC9 other 1 1 1 0.653229499409808 -2.04950331585724 3.08188657516459e-09 4.35818929173692 106.493851681481 0.0409243277703214 0.967374913331356 -945.031597807753 186.078265582088 -5.07867802212964 5.63881744971707e-07 CAB39 other 2.15177320677992e-05 0.00501178094930853 1 0.0409243277703214 -5.07867802212964 0.000818519406872349 132.4597202209 112.945068335267 1.17278002637269 0.241522911033433 -429.878178666856 188.937642547818 -2.27523839543017 0.0233751402917448 ISCU essential 1 1 1 1.17278002637269 -2.27523839543017 0.000278845535625761 113.802704716062 86.2797770136027 1.31899627763433 0.187859517776375 -371.477404760542 149.395768169673 -2.48653231153539 0.013271051119111 ALDH1L2 other 1 1 1 1.31899627763433 -2.48653231153539 0.39874694490473 4.4883720930232 4.02024832536618 1.11644150554167 0.264845281726685 8.48892580287929 6.6666901962036 1.27333437628666 0.203574774963893 USP44 other 1 1 1 1.11644150554167 1.27333437628666 6.75077460673418e-05 201.118144169796 69.2143608947716 2.90572854491224 0.00385012810776681 -147.116021741938 120.326589145303 -1.22263934170264 0.222124926099414 SCYL2 other 0.341791718338951 1 1 2.90572854491224 -1.22263934170264 1.32282217968179e-10 617.624311691636 103.027931143512 5.99472691372714 4.26398314069342e-09 96.0765783070834 174.54150568873 0.55045118310382 0.582290566741061 CKAP4 other 9.70554633232531e-07 1 3.99236741463125e-05 5.99472691372714 0.55045118310382 0.956211601136783 -1.46484479828212 113.94245690682 -0.0128560050226057 0.989748528236236 -44.8198854995964 181.432534195268 -0.247033343266642 0.804998165340783 PLXNC1 other 1 1 1 -0.0128560050226057 -0.247033343266642 0.0617344012744843 -50.9969266231262 148.624170432157 -0.343126736888366 0.731667743238581 -534.644256626969 251.786930020293 -2.1233995608266 0.0342804185522242 APPL2 other 1 1 1 -0.343126736888366 -2.1233995608266 3.42003103824548e-12 134.48598919649 57.5317884344991 2.33759444745237 0.019857784670988 -429.379350561657 96.2347573997923 -4.46179075173294 1.0346838576102e-05 PWP1 essential 2.60606365114306e-08 0.0875963353852792 1 2.33759444745237 -4.46179075173294 0.0587720948505707 25.7457260256256 36.2445475788563 0.710333767295929 0.47787607818952 -96.1204057202007 63.0097963616085 -1.52548351638169 0.12786191893401 DRAM1 other 1 1 1 0.710333767295929 -1.52548351638169 0.0172577507582306 171.424330983898 88.157841640702 1.94451597037231 0.0524730382014733 -102.461891936877 152.647687881908 -0.671231208009808 0.502427078984768 WASHC4 other 1 1 1 1.94451597037231 -0.671231208009808 0.00146920722925186 57.4552174660477 29.2044612115749 1.96734386057688 0.0497742362658208 -73.7346365742449 50.5683147048094 -1.45811931848368 0.14552430649188 SLC41A2 other 1 1 1 1.96734386057688 -1.45811931848368 0.0407200056220692 -7.11273245554487 34.3110660880807 -0.207301412240751 0.835870814653417 -130.007428019848 58.3679511250348 -2.22737693398468 0.0264295093253694 VILL other 1 1 1 -0.207301412240751 -2.22737693398468 0.0677345310122598 -145.023558217249 207.608039321717 -0.698545001874976 0.485208843659194 -787.590659431555 348.178972733281 -2.26202821281479 0.0241872476327205 FLNB other 1 1 1 -0.698545001874976 -2.26202821281479 0.00128853187311952 23.0712034880123 27.3602317879503 0.843238597787505 0.399557381114135 -48.9321149168886 31.7484140245992 -1.54124596204948 0.123982374346531 NEK3 other 1 1 1 0.843238597787505 -1.54124596204948 0.00207132417982348 -43.6166208475608 75.4387461134732 -0.578172664507887 0.563446737881496 -228.36131863953 87.549393198162 -2.60837123248416 0.00941057853272591 PCDH8 other 1 1 1 -0.578172664507887 -2.60837123248416 6.33293950851513e-16 107.268639925211 69.9293717561279 1.53395686578309 0.12576722104045 -331.064973340412 81.155565003277 -4.07938720317015 5.37149248450584e-05 VPS36 other 5.16767863894834e-12 0.436165189741874 1 1.53395686578309 -4.07938720317015 1.82610735176036e-10 64.0958961495842 39.5365303857427 1.62118161417366 0.105701616943062 -129.107326668782 45.8340971212057 -2.81684018619076 0.00507012446015597 RNASEH2B other 1.33305836678506e-06 1 1 1.62118161417366 -2.81684018619076 2.6837762796907e-09 685.247320176512 115.453451106968 5.93526926745245 5.99906670638664e-09 422.4033480958 133.987905523306 3.15254833222485 0.00173051045841505 CKAP2 other 1.8802536615513e-05 1 5.60312830376512e-05 5.93526926745245 3.15254833222485 0.512062282921409 -15.9047662433351 15.8033864469696 -1.00641506785306 0.314775436599372 -21.0072307038186 18.3404015202891 -1.14540735002881 0.252670215835811 CNMD other 1 1 1 -1.00641506785306 -1.14540735002881 0.00465766105746123 -8.91115730517179 56.9802470138732 -0.156390289129532 0.875798111447592 -147.625951467449 66.2451606962244 -2.22847903025561 0.0263601165265914 TBC1D4 other 1 1 1 -0.156390289129532 -2.22847903025561 0.123798600847869 -12.0531290355805 43.2721696974428 -0.278542285257602 0.780728468878179 -73.8496605160793 50.2189179242257 -1.47055459513305 0.142134556259606 THSD1 other 1 1 1 -0.278542285257602 -1.47055459513305 8.3724752936825e-10 56.1580779309215 13.4931946282131 4.16195567308426 3.80625325247303e-05 -1.1213984764011 15.6681536045151 -0.0715718332042608 0.942975625985667 BORA essential 5.97878460721867e-06 1 0.322465775549515 4.16195567308426 -0.0715718332042608 0.500422608719986 17.1980998094535 33.9751356278522 0.506196649156414 0.6129744584671 -10.8011393231311 40.3714826561969 -0.267543786169893 0.789177019697499 LRCH1 other 1 1 1 0.506196649156414 -0.267543786169893 2.39970726812674e-18 123.853964170067 74.0261718089617 1.67311048435269 0.0950228375982944 -391.635881757825 87.8551235450291 -4.45774663963789 1.05465502074513e-05 SUCLA2 other 2.0183937832214e-14 0.0892449078554527 1 1.67311048435269 -4.45774663963789 6.2776413233974e-17 136.683756092306 133.017771970242 1.02756010770414 0.304727829172049 -738.303530172062 156.682076266288 -4.71211224516379 3.30447473784659e-06 RCBTB1 other 5.19663148750836e-13 0.0285704885834216 1 1.02756010770414 -4.71211224516379 4.76811068279346e-39 140.159827191328 33.8319285932794 4.14282699861131 4.12152773270321e-05 -222.405851693386 40.1521271963077 -5.53908017391014 5.26628420778884e-08 MED4 essential 4.44101828995382e-35 0.000480706422486965 0.348681246186692 4.14282699861131 -5.53908017391014 0.329094914549541 -68.0724169965265 45.8703740087707 -1.48401704733235 0.138528601590124 -68.5497536149928 54.0308661944301 -1.26871468927254 0.205221327161903 PHF11 other 1 1 1 -1.48401704733235 -1.26871468927254 2.37638862287727e-30 157.895492206153 37.0046710486175 4.26690706150872 2.43185305798991e-05 -184.486818756302 44.2993142384057 -4.16455247508909 3.76010989289623e-05 COG3 essential 2.15348337005138e-26 0.308629820008923 0.207996392049877 4.26690706150872 -4.16455247508909 0.03840911512629 172.644993153135 77.9571396223801 2.21461426098261 0.0273053259648898 79.375174255789 90.6328686227914 0.875787950463575 0.381629769970531 LMO7 other 1 1 1 2.21461426098261 0.875787950463575 5.55644566914934e-12 -365.411965377997 1153.34266686046 -0.316828619869491 0.751525640231953 -6676.94156412559 1370.65898736655 -4.87133679906336 1.55490798444157e-06 ITM2B other 4.21067452808137e-08 0.0136287684836304 1 -0.316828619869491 -4.87133679906336 0.109345191169425 -123.004147987835 260.767735137832 -0.471700028083687 0.637380728232573 -514.146596588856 304.119667376329 -1.69060620453932 0.0916384046728569 SPRY2 other 1 1 1 -0.471700028083687 -1.69060620453932 3.19058428929051e-08 33.2321016331676 18.4953804448263 1.79677848381127 0.0730627988689314 -46.9916277894889 21.9505330923491 -2.1407966536297 0.0328444323637313 NUDT15 other 0.000211822890965997 1 1 1.79677848381127 -2.1407966536297 0.00561396611232963 -1585.10371539009 2097.79818037565 -0.75560353241714 0.450299676248628 -6365.4370056007 2442.81135551565 -2.60578328786139 0.00948378770737583 EDNRB other 1 1 1 -0.75560353241714 -2.60578328786139 0.000437131640508354 41.0295245988446 100.28126636413 0.409144460241085 0.682635483175204 -259.176806008619 119.498497405472 -2.1688708363353 0.0306348567276068 RCBTB2 other 1 1 1 0.409144460241085 -2.1688708363353 0.025193810957003 -179.669091419752 188.140679056592 -0.954972057721275 0.340119783881515 193.772548543992 225.228405668165 0.860337966559524 0.39007452009321 LCP1 other 1 1 1 -0.954972057721275 0.860337966559524 4.39224100571428e-14 28.8850176373967 15.1496610907574 1.90664447635856 0.0572252299243044 -60.0621536473056 17.8448362145284 -3.36580021947222 0.000830952746452631 SETDB2 other 3.48129022112914e-10 1 1 1.90664447635856 -3.36580021947222 6.87871381347789e-20 3549.33699776725 359.184253041629 9.88166092391552 6.37682747230507e-21 2517.27267937087 1337.51437841353 1.88205279883173 0.0604916086971886 TTYH3 other 5.8654792687526e-16 1 6.23908799890328e-17 9.88166092391552 1.88205279883173 0.00251265949682309 -256.758957122518 99.8436658922187 -2.57160987457822 0.0104530384898685 -1110.12421165651 397.92324571187 -2.78979482505612 0.00550535434128052 MMD2 other 1 1 1 -2.57160987457822 -2.78979482505612 3.50667332616601e-19 115.587590427666 28.0679436215662 4.11813533567359 4.56661727566999e-05 -163.597358183508 41.6288923205167 -3.92989938151392 9.87322184680589e-05 CIDEB other 2.97436031525401e-15 0.786402120098089 0.385696495103087 4.11813533567359 -3.92989938151392 2.99375987737589e-11 18.5096187006132 22.4912096688375 0.822971239570945 0.410972178720452 -143.710213751283 31.3530962350933 -4.58360516210928 5.97000593278949e-06 TTC5 other 2.23154861259599e-07 0.0510793707609469 1 0.822971239570945 -4.58360516210928 4.58240519328953e-09 65.4981287425152 20.8742556659639 3.13774679158078 0.00181771096963382 -67.6734923011123 31.1298989399215 -2.17390658516808 0.030248232714639 ZFHX2 other 3.17469031791099e-05 1 1 3.13774679158078 -2.17390658516808 0.00183973506013822 -1.22897737075082 19.081703783312 -0.0644060606278579 0.948676355189689 -106.163016130886 34.969551662003 -3.03587009513308 0.00254180972349878 MTHFS other 1 1 1 -0.0644060606278579 -3.03587009513308 8.41652558202075e-06 144.725573638509 30.5020288439047 4.7447851544285 2.83182007913208e-06 86.7203979527288 55.898691519657 1.55138511466289 0.121533301787116 ADAMTS7 other 0.0471577928360623 1 0.0250955895412685 4.7447851544285 1.55138511466289 5.90651224703661e-07 -107.235819466061 60.5350864668314 -1.77146553717764 0.0771801904218758 -632.782401532381 118.678947366572 -5.33188417637257 1.56188880119174e-07 ABHD17C other 0.00364195545152277 0.00140976083195566 1 -1.77146553717764 -5.33188417637257 7.700563101597e-05 133.239472511362 83.5343149212722 1.59502681786443 0.111429159652267 -394.409903530963 153.086829895356 -2.57638037054243 0.0103113199672716 IREB2 other 0.387107307117281 1 1 1.59502681786443 -2.57638037054243 0.996856446276022 -3.58771359811373 65.1080545582186 -0.0551039901661577 0.956080858417079 2.43657119719492 123.595058152472 0.0197141474231848 0.984280423393491 ALPK3 other 1 1 1 -0.0551039901661577 0.0197141474231848 0.00224043145083774 -26.5137396678723 33.301821138883 -0.796164857089905 0.42636949466795 -218.925161638741 65.2909417628137 -3.35307097321468 0.000868941404236057 TM6SF1 other 1 1 1 -0.796164857089905 -3.35307097321468 0.000486190064652427 87.1647150607149 36.8188518237294 2.3673936242775 0.0183506105009015 -91.6663512312826 67.4809202875802 -1.35840398798108 0.175039568415346 CIB2 other 1 1 1 2.3673936242775 -1.35840398798108 0.416967333096881 -157.703513900563 162.611089031775 -0.969820169335109 0.33267136856833 -395.606440770243 370.176599806561 -1.06869651127859 0.285795068121062 CALCOCO2 other 1 1 1 -0.969820169335109 -1.06869651127859 0.000548701966160046 482.734737065292 140.919888030379 3.42559693888789 0.000671294573841053 -377.235314025225 315.612345032308 -1.19524891837361 0.232636540517833 NMT1 essential 1 1 1 3.42559693888789 -1.19524891837361 0.0916551696060925 298.230919580226 151.775792197307 1.96494391669871 0.0500523595370453 -236.552237844247 361.185220236818 -0.654933326699101 0.512854472816913 KAT7 other 1 1 1 1.96494391669871 -0.654933326699101 0.312806687281255 10.8297250537734 19.6279504109395 0.551750173963021 0.581402204580668 -43.7741123476421 41.5811621634037 -1.05273903061248 0.293043691759689 RTP4 other 1 1 1 0.551750173963021 -1.05273903061248 6.38632210790855e-33 180.384777367775 26.3944802340842 6.83418562396379 2.77485684553536e-11 -295.107680196801 53.2247958768725 -5.54455259686647 5.10244013278854e-08 STAM other 5.84603925757949e-29 0.000466005857327577 2.6486008590635e-07 6.83418562396379 -5.54455259686647 0.0522202069331451 -110.030334576791 72.3602841057181 -1.52059014052567 0.129089237459718 -343.613461470494 141.163707127061 -2.43414875157118 0.0153282881471863 GAD2 other 1 1 1 -1.52059014052567 -2.43414875157118 7.86584197066176e-37 604.030181129804 99.6479814772509 6.06163990655145 2.91451002944634e-09 -1348.53992521697 193.879969015634 -6.95554023483584 1.28835460149262e-11 ABI1 other 7.28770258581812e-33 1.22857494798336e-07 2.7346847606295e-05 6.06163990655145 -6.95554023483584 2.41274752679155e-18 511.985092285849 79.656586947029 6.42740433539182 3.4020713435232e-10 -294.216843780922 154.983737555255 -1.89837236100999 0.0583056034496852 YME1L1 other 2.02912067003169e-14 1 3.22210176945083e-06 6.42740433539182 -1.89837236100999 9.46134893303263e-07 90.7821592488107 20.2363368978811 4.48609645643507 9.28577523084686e-06 197.361094629821 39.686159546078 4.97304594063008 9.48795106606313e-07 DNAJC1 other 0.00574398493724411 0.00837406561090732 0.0807491014074443 4.48609645643507 4.97304594063008 0.0269547983811034 52.6486730907155 37.1652486956159 1.41661027272841 0.157307719638073 -131.292252679287 81.5708581281313 -1.60954850411226 0.108216911909517 NIPSNAP3A other 1 1 1 1.41661027272841 -1.60954850411226 0.00147826693705302 -1123.8081788899 1013.60036013529 -1.10872906432264 0.268156884665632 -8133.00315111341 2240.33468660611 -3.63026256734619 0.00031666014389141 LRRC8A other 1 1 1 -1.10872906432264 -3.63026256734619 1.20878658335602e-12 603.632024882031 80.5723356610903 7.49180248939383 3.78493973165565e-13 253.210960960958 166.667401233366 1.51925906978303 0.129418783509388 TXN essential 9.29436003942445e-09 1 3.64868190131604e-09 7.49180248939383 1.51925906978303 1.57425622942362e-05 281.717228420712 59.5293184563963 4.73241145246879 3.00110141044773e-06 160.134634237433 131.576114465946 1.21704942335014 0.224242256224323 ODF2 other 0.0858127070658814 1 0.0265687507866937 4.73241145246879 1.21704942335014 1.8531254456371e-06 234.767374517375 92.6647604211889 2.53351299296829 0.0116402935244339 -614.682432432429 191.68111087501 -3.20679711019228 0.00144058054501608 KIAA0368 other 0.0109927401435193 1 1 2.53351299296829 -3.20679711019228 6.46378834748671e-05 109.777774791002 26.8519924408268 4.08825434585224 5.17356812870659e-05 -2.94492621166004 58.2656814381218 -0.0505430665011195 0.959712724580047 TOR1B other 0.327843344984526 1 0.435769643480956 4.08825434585224 -0.0505430665011195 6.60828180412562e-12 285.8505819736 68.2851131695222 4.18613323908474 3.43252767650937e-05 -599.051127657866 148.170705010781 -4.0429795323865 6.23761853629603e-05 C9orf78 essential 4.99850435664062e-08 0.503687696805904 0.29145592501241 4.18613323908474 -4.0429795323865 0.00143164965404966 276.072067857921 77.83544593796 3.54686819778702 0.000431898806307191 90.2764420328287 170.834431109138 0.528444069773941 0.597458805236312 SMC2 essential 1 1 1 3.54686819778702 0.528444069773941 0.196553399161718 -30.8809881309884 48.643243354166 -0.634846404178836 0.525860068787557 -181.670920920919 100.620676946767 -1.8055028691273 0.0716825094114078 KLF4 other 1 1 1 -0.634846404178836 -1.8055028691273 3.52473798205363e-09 160.849506733692 32.2388805196423 4.98930186597795 8.76294835688494e-07 -124.62456385581 69.954598207883 -1.78150639198106 0.0755241503862318 TOR1A other 2.45180774031651e-05 1 0.00787263280382543 4.98930186597795 -1.78150639198106 9.84161585309469e-07 185.92474125988 50.4995540752072 3.68171055496824 0.000260597496218061 -253.384809713959 111.617105937882 -2.27012524276499 0.0236850723579635 RALGPS1 other 0.00596992417648724 1 1 3.68171055496824 -2.27012524276499 0.73863735489033 198.670720321177 256.992396359851 0.77306069414984 0.439904398453418 110.290089164835 568.023653505953 0.19416460649852 0.846137220194619 FAM129B other 1 1 1 0.77306069414984 0.19416460649852 7.3322166803683e-07 118.920829598239 22.2838652295086 5.3366338547391 1.52239344649571e-07 57.0535001222396 49.2531189943451 1.15837334339761 0.247342915921072 ST6GALNAC4 other 0.00448658338671736 1 0.00138887954123804 5.3366338547391 1.15837334339761 3.01134706525651e-08 1345.84418346588 252.889223904988 5.32187240991939 1.64481353594009e-07 -331.275383761791 551.475443037257 -0.600707407635938 0.548346302750507 TMOD1 other 0.00020040514719282 1 0.00149957650071658 5.32187240991939 -0.600707407635938 0.00143507189256166 310.536858168927 158.720012723672 1.95650726609734 0.0510404575297544 -667.597580254581 325.40040961399 -2.05161874579853 0.0408008304340464 DAB2IP other 1 1 1 1.95650726609734 -2.05161874579853 0.332994830321807 -622.504026422696 761.193213323733 -0.817800284509299 0.413916900993021 -2442.66721908409 1682.44569170309 -1.45185501744871 0.147259460113489 STXBP1 other 1 1 1 -0.817800284509299 -1.45185501744871 1.52626529988599e-16 228.297286284735 26.7778486129213 8.52560224627505 2.48704600163349e-16 42.1884524488628 59.1859872854677 0.712811501232178 0.476341973901355 SLC2A8 other 1.2558110887462e-12 1 2.41765741818791e-12 8.52560224627505 0.712811501232178 0.791871351556377 -474.333795126713 915.028273081184 -0.518381572549102 0.604453835015821 -1219.93089397766 2022.44969412119 -0.603194678969631 0.546691399698181 ANGPTL2 other 1 1 1 -0.518381572549102 -0.603194678969631 3.02859775983522e-08 425.982190015811 75.8901251699091 5.61314385846757 3.53124867741181e-08 41.4649024212676 155.586415299363 0.266507216208339 0.789974020842151 CDK5RAP2 other 0.000201522894939435 1 0.00032551050308382 5.61314385846757 0.266507216208339 0.000314144068145202 66.2665949049157 21.5403518632539 3.07639333496502 0.00222683905408023 -50.3105938284898 43.5732149476735 -1.15462202843896 0.248876235364377 ZFP37 other 1 1 1 3.07639333496502 -1.15462202843896 0.509615620196112 -30.1603875134567 113.915628760298 -0.264760751809748 0.791318604836605 -262.927206673846 230.435891176851 -1.140999370068 0.254495072192356 SLC31A2 other 1 1 1 -0.264760751809748 -1.140999370068 0.844911955931023 36.649085037678 63.1271097122334 0.580560161945379 0.561836180782709 28.9461786867625 127.697594634417 0.226677556218908 0.820780474346446 SLC31A1 other 1 1 1 0.580560161945379 0.226677556218908 0.0303541473236837 -29.2363935546046 184.499982163505 -0.158462853013694 0.874165290834306 -936.539389611606 375.448152813503 -2.49445731079896 0.0129833464088053 TLR4 other 1 1 1 -0.158462853013694 -2.49445731079896 0.000170914351424119 77.7573985717397 44.7923102294758 1.73595418886367 0.0832751589303716 -286.679899377348 98.3108498179059 -2.91605555143043 0.00372691463978093 ZNF189 other 0.822098030350014 1 1 1.73595418886367 -2.91605555143043 0.0813221118642802 4.72203511398012 19.7539182434423 0.239042961289349 0.811184079051665 -86.1222700387736 43.3562028794015 -1.98638866688416 0.0476129576979274 STX17 other 1 1 1 0.239042961289349 -1.98638866688416 2.69001536473682e-05 153.500986724077 37.8459498232062 4.05594224589798 5.91342405519113e-05 -31.3022515249366 76.5572316095082 -0.408873869481051 0.682832525694799 PRPF4 essential 0.143135717557646 1 0.497141560319918 4.05594224589798 -0.408873869481051 8.2149341707608e-09 308.552114742073 49.5805768646055 6.22324575981974 1.14010958988673e-09 210.436476244805 109.585928068123 1.92028739414415 0.0554706566657497 FPGS other 5.63544484114191e-05 1 1.07432526655027e-05 6.22324575981974 1.92028739414415 3.57695786745733e-18 410.368377793528 59.82159915274 6.85986973945232 2.37209864964077e-11 -431.570500780151 129.807226491675 -3.32470319599524 0.000959893541452782 USP20 other 2.99892147607623e-14 1 2.26511700054197e-07 6.85986973945232 -3.32470319599524 1.56998699830647e-06 304.754391211422 71.8781008938084 4.23987817460093 2.72957433766214e-05 -180.008528815903 149.761228273149 -1.20197016872476 0.230024534132658 ATP6V1G1 essential 0.00936811241889471 1 0.232887282489334 4.23987817460093 -1.20197016872476 8.38586763973012e-07 194.61168802819 41.5390197198251 4.68503323720249 3.74148010353017e-06 -64.9486179977343 91.1704778864349 -0.712386503870657 0.476604773007018 TEX10 essential 0.00510783197935961 1 0.0330148204335502 4.68503323720249 -0.712386503870657 0.0515735643353991 8.22357591068311 39.5580353451856 0.2078863583321 0.835414326930514 -191.692771575259 87.4335130809754 -2.19244045927476 0.0288731391321933 GARNL3 other 1 1 1 0.2078863583321 -2.19244045927476 5.3461442192882e-10 126.369226931112 30.0841544722489 4.2005244670473 3.22800814609073e-05 -217.134037068224 66.0291638691518 -3.2884565598697 0.00108860859678617 MRPL50 essential 3.85029306673136e-06 1 0.274445252580634 4.2005244670473 -3.2884565598697 9.25867132186076e-11 452.491035775403 65.5430500535331 6.90372259767931 1.78720446877865e-11 223.900293374622 144.867131904215 1.54555619643704 0.122933973225446 DPM2 other 6.82271489707919e-07 1 1.70874619259926e-07 6.90372259767931 1.54555619643704 0.821386848241265 -11.3494825197619 29.1982148515834 -0.388704671756548 0.697683506052106 -38.7303805720805 64.535624125169 -0.600139552334097 0.548723599170598 WDR38 other 1 1 1 -0.388704671756548 -0.600139552334097 2.39003345547545e-17 960.643980025896 112.624172893791 8.52964292960285 2.42768050435262e-16 26.2485296837422 245.599494846973 0.106875340684625 0.914936922313623 TSTD2 other 1.98587879815455e-13 1 2.36043375438205e-12 8.52964292960285 0.106875340684625 0.02826654656628 269.583443928328 475.053657605144 0.567479988023586 0.570678860138192 -2237.88941801009 1018.68113031181 -2.1968497809762 0.0285543403836151 GABBR2 other 1 1 1 0.567479988023586 -2.1968497809762 6.89472179718112e-12 917.834022323268 132.330919256395 6.93589999586518 1.45632859962608e-11 49.0743223291819 290.546262086985 0.168903643697504 0.865950405286111 PSMB7 essential 5.21172020648921e-08 1 1.39297830554235e-07 6.93589999586518 0.168903643697504 0.00102242644051327 58.4523592206051 20.068735392458 2.91260799833816 0.00376792612355799 -44.0759950791694 42.7607579935143 -1.0307580395524 0.303224434163208 TRMO other 1 1 1 2.91260799833816 -1.0307580395524 1.2035978681759e-10 157.745025486795 31.1877619040062 5.05791425406939 6.25054595967327e-07 -176.523183806856 68.4765497590284 -2.57786328937494 0.0102678501752342 RABEPK other 8.83801914601566e-07 1 0.00563424212804949 5.05791425406939 -2.57786328937494 2.16685304988222e-11 209.819493113844 38.1938123416752 5.49354673570776 6.69282137120945e-08 -198.575910683725 84.4182265840106 -2.35228716260828 0.0191000842896034 GOLGA1 other 1.6208060813119e-07 1 0.000614334073663316 5.49354673570776 -2.35228716260828 6.9321184138908e-10 77.2861370181522 14.8675326385239 5.19831628402772 3.09405791683266e-07 -62.3561837829261 32.4216232787415 -1.92328999837008 0.0550930472168729 XPA ts 4.96755605539415e-06 1 0.00280692934215059 5.19831628402772 -1.92328999837008 6.74177433641241e-07 240.333720838071 57.7434585839562 4.1620943173786 3.79925838729022e-05 -210.702692277204 125.921140147335 -1.67329085513894 0.0949856755060234 NCBP1 essential 0.00413540437795537 1 0.321949155738973 4.1620943173786 -1.67329085513894 7.63167236668004e-09 954.189848803534 161.457735555844 5.90984287942961 6.90090011271183e-09 147.955511627446 344.02043882042 0.430077678334336 0.667351139554617 ANP32B other 5.24295891590919e-05 1 6.43784971514887e-05 5.90984287942961 0.430077678334336 1.15071728378462e-06 132.489331371708 31.9970538264204 4.14067282851866 4.15555109113785e-05 -93.1060679441603 65.5988759255259 -1.41932413674074 0.156515798484077 PDCL other 0.00693307163480232 1 0.351434955777528 4.14067282851866 -1.41932413674074 2.99370177694206e-09 2627.0394425882 420.444928605605 6.24823672222831 9.84615692281021e-10 878.038709151659 929.292287756195 0.944846654513523 0.345258080752779 RPL35 essential 2.09289691226019e-05 1 9.28492597821003e-06 6.24823672222831 0.944846654513523 0.689323581982565 7.98136014161527 16.0425207217779 0.497512846019297 0.619077681544849 29.371550107004 34.9839193851959 0.839572884433101 0.401606969064815 CTSV other 1 1 1 0.497512846019297 0.839572884433101 7.4380926523497e-05 191.454241708091 45.7330060391983 4.18634719843243 3.42796729111165e-05 23.7887702713715 101.081799105254 0.235341777470749 0.814053463497567 ARPC5L other 0.37451023107689 1 0.291102982361201 4.18634719843243 0.235341777470749 2.10737171286567e-09 172.916741906504 102.390897650996 1.68879017445376 0.0919746367951909 -399.577239285431 117.931278114708 -3.38822105274542 0.000767367173194958 IL33 other 1.48211452565843e-05 1 1 1.68879017445376 -3.38822105274542 4.25376820968926e-21 277.191808144096 46.503113923288 5.96071498784693 5.18779667933162e-09 -105.359720721848 53.5611249349554 -1.96709312677425 0.0498061281691895 RANBP6 other 3.6769572404554e-17 1 4.85007111550713e-05 5.96071498784693 -1.96709312677425 1.50754054836969e-06 169.170380078637 36.3927575873359 4.64846280671803 4.44353567479959e-06 11.1376146788989 42.8811964993545 0.25973190088263 0.79519374836818 POLR1E essential 0.00900303215486378 1 0.0391075574739112 4.64846280671803 0.25973190088263 1.20883153678607e-13 162.514991626948 29.7884091886923 5.45564520070575 8.38271797696201e-08 -22.0374648975909 33.5431333944322 -0.656988857852165 0.511550504936289 PLAA other 9.50625120528566e-10 1 0.000768276102588568 5.45564520070575 -0.656988857852165 0.068648739984991 206.956239763856 95.4144631796953 2.16902378179388 0.0306244209094154 62.9454103763748 111.246142615854 0.565821060364605 0.571808524175651 IL11RA other 1 1 1 2.16902378179388 0.565821060364605 3.38760302066326e-07 178.220034627641 56.5552010655664 3.15125808537086 0.00173773791826009 -123.374438656435 65.8735409180662 -1.87289823709171 0.061751363133012 UBAP2 other 0.0021165743673104 1 1 3.15125808537086 -1.87289823709171 7.4394165823036e-22 169.172495949084 20.5974279736147 8.21328255963774 2.4802909954823e-15 -2.07115274320805 23.9744170192421 -0.0863901191651803 0.931196051378881 APTX other 6.46485301002183e-18 1 2.40588226561783e-11 8.21328255963774 -0.0863901191651803 2.17513088871937e-08 326.561495481823 92.2904654817185 3.53840988640924 0.000445982865717955 -263.811240438129 108.744867047822 -2.42596499126818 0.0156744140955839 RNF38 other 0.000145973033941957 1 1 3.53840988640924 -2.42596499126818 0.0485267067645489 316.696324716406 131.487244034299 2.40857070997544 0.0164319549734344 134.58582131201 153.457529140875 0.87702325239747 0.380960328563205 DNAJB5 other 1 1 1 2.40857070997544 0.87702325239747 0.000214876536730705 129.645838421974 38.7720641488186 3.34379510784764 0.000897927926951041 -15.4638075481706 45.63446776149 -0.338862449957621 0.734876865489434 SPAG8 other 1 1 1 3.34379510784764 -0.338862449957621 2.89730841520573e-14 595.697047767875 79.8837973168718 7.45704470463451 4.87149486993992e-13 140.298644253918 93.138545382498 1.50634351951433 0.132708169445491 DCTN3 essential 2.3039396517716e-10 1 4.6951467556481e-09 7.45704470463451 1.50634351951433 1.72188022369141e-05 128.2094618591 28.5418596022347 4.49197997768377 9.05896265189875e-06 35.5933257319451 33.3484368008453 1.06731616670689 0.286422426510569 CD72 other 0.0935153149486803 1 0.0788310929968229 4.49197997768377 1.06731616670689 3.65984458791345e-07 339.768572958902 74.4273850549943 4.56510157797224 6.50671795732931e-06 -24.1266871026499 87.6005489629737 -0.275417076585303 0.783126602918524 TMEM8B other 0.00228081514718766 1 0.0569012485368448 4.56510157797224 -0.275417076585303 2.0028894589896e-14 636.09419190177 108.985981763896 5.83647714693972 1.04474184116939e-08 -259.433670487178 128.417015074422 -2.02024373745821 0.0439719229685672 GRHPR other 1.59570203197702e-10 1 9.71923334839886e-05 5.83647714693972 -2.02024373745821 0.00053835950896301 133.554497178641 35.4092796365095 3.7717371985432 0.000184648435975414 41.5508156258737 41.4294317381187 1.00292989506885 0.316454821729154 ALDH1B1 other 1 1 1 3.7717371985432 1.00292989506885 1.63705450926136e-05 221.975781266356 47.6354654391816 4.65988479843369 4.21237924046234e-06 91.9216788328801 56.0666335314041 1.63950772577406 0.101830507893932 HINT2 other 0.0890885063940033 1 0.0371068487292327 4.65988479843369 1.63950772577406 2.39079791214311e-07 227.516150296638 40.9801609087842 5.5518608334178 4.92495123547122e-08 106.169572882988 47.8558543053875 2.21852842090075 0.0270343651299543 ARHGEF39 other 0.00150811532297987 1 0.000453046264150998 5.5518608334178 2.21852842090075 0.107307367604884 39.7966959503861 22.5100244685509 1.76795436211038 0.0777726958595664 -3.0041706639072 26.3370938837643 -0.114066140978415 0.909238232779898 IGFBPL1 other 1 1 1 1.76795436211038 -0.114066140978415 9.94512784693952e-08 161.221946094176 65.8745191862187 2.44740983442206 0.014784102105681 -150.716619037683 74.316061787734 -2.02804905712265 0.0431655647030685 DENND4C other 0.000641560197406068 1 1 2.44740983442206 -2.02804905712265 3.74364128355869e-13 8359.88156183186 1733.04613341463 4.82380786099465 1.95437500216678e-06 -1989.40942391935 1955.75097472377 -1.01720998717658 0.309621570590474 RPS6 essential 2.91105546209524e-09 1 0.0173958918942865 4.82380786099465 -1.01720998717658 4.84569301869322e-11 760.507662977092 107.461505266214 7.07702410359031 5.88269821312657e-12 755.580294672931 267.519977265501 2.82438830324456 0.00495335363058501 CNPY3 other 3.59792706637972e-07 1 5.64386066567363e-08 7.07702410359031 2.82438830324456 0.00820248183069757 -60.270588235295 74.1398021178947 -0.812931603721502 0.416698922765136 -534.035595776769 172.807608065169 -3.0903477095486 0.00212667196008046 FOXP4 other 1 1 1 -0.812931603721502 -3.0903477095486 1.03167632347782e-13 302.286183792035 50.7077875256546 5.9613364838507 5.15333481042446e-09 -316.929399375203 119.05043332484 -2.66214402185696 0.00805018211394542 PPIL1 other 8.12238769474086e-10 1 4.81836804774687e-05 5.9613364838507 -2.66214402185696 1.30086348043184e-06 71.0320984600176 45.9599988563638 1.54552002235705 0.122944367372492 -476.137114230938 114.417549712148 -4.16139932579229 3.81039699720397e-05 KLC4 other 0.00780518088259104 0.312566865680641 1 1.54552002235705 -4.16139932579229 0.0200467241990262 38.2101821875198 225.640560748505 0.16934092904559 0.865606842449115 -1039.91777227618 433.338979933389 -2.39977897311714 0.0168226021700188 KIF13A other 1 1 1 0.16934092904559 -2.39977897311714 4.74432323226083e-08 49.1677217429997 16.2072510691866 3.03368668339308 0.00255955506250663 -107.502118579793 32.9784687405188 -3.25976683228204 0.00120199460885717 ZSCAN9 other 0.000311796922824182 1 1 3.03368668339308 -3.25976683228204 0.278444187438712 120.462363767439 83.228390263982 1.44737106395257 0.148508361213036 231.738412281073 195.401464140848 1.18596047015305 0.236280861273496 PIM1 og 1 1 1 1.44737106395257 1.18596047015305 0.245311773039673 -49.5369844489514 125.965809980112 -0.393257380369898 0.694321612691463 304.701104349788 241.925600070554 1.25948268501112 0.208529851484478 GMPR other 1 1 1 -0.393257380369898 1.25948268501112 2.89222213466877e-09 242.76703702133 69.6556390026713 3.4852459972698 0.000541243873861029 -596.309613672025 163.535709433017 -3.64635721298698 0.000297955630262045 CMTR1 essential 2.02368782762774e-05 1 1 3.4852459972698 -3.64635721298698 0.105458424154256 61.9984770607273 55.0114717307974 1.12700996919554 0.260359560861553 -89.0993717875501 95.2336881076421 -0.93558669792187 0.350005111402278 TFAP2A other 1 1 1 1.12700996919554 -0.93558669792187 5.93836437886203e-11 476.935642098256 94.2221437466097 5.06182117211079 6.12549145272177e-07 -646.75406902849 234.561256987387 -2.75729281696025 0.00607187220192525 YIPF3 other 4.39432302319765e-07 1 0.00552213054462867 5.06182117211079 -2.75729281696025 6.19441073809006e-08 136.317437654674 42.7778916853704 3.18663291443354 0.00154311631942912 -185.495526365887 74.0553972924586 -2.50482116291039 0.0126160732738162 TMEM14B other 0.000403689747801329 1 1 3.18663291443354 -2.50482116291039 0.0168856704182998 52.5231458033671 75.8759993862761 0.692223446520654 0.489165501977868 -337.575342882033 153.342919355401 -2.20144069449754 0.0282280443436534 TMEM63B other 1 1 1 0.692223446520654 -2.20144069449754 1.3483819428285e-07 30.1532212885153 17.6757938065828 1.70590478812248 0.0887347251371429 -181.095546936723 41.1993498918641 -4.39559234337542 1.38787901347132e-05 FRS3 other 0.000861885737855978 0.116581837131591 1 1.70590478812248 -4.39559234337542 0.00518184716071994 158.185595824236 70.3924346849025 2.24719597400376 0.0251246031452069 -245.200206073617 175.238402625364 -1.39923785197827 0.162449438248131 TJAP1 other 1 1 1 2.24719597400376 -1.39923785197827 0.566071793221368 -53.7890111125288 54.2163234352654 -0.992118382515429 0.321687542443164 -12.8040663077063 104.414306867014 -0.122627508546449 0.902458315310805 KIAA0319 other 1 1 1 -0.992118382515429 -0.122627508546449 0.563569437867812 -0.692750188808864 4.49194330414465 -0.154220599393958 0.877507987766772 -7.5960031294798 7.69489442309424 -0.987148453483957 0.324123704821547 IRF4 other 1 1 1 -0.154220599393958 -0.987148453483957 0.193965136563442 151.535468179977 117.948401183595 1.28476068059712 0.199561206265086 -88.8549461588612 203.540320285304 -0.436547147190848 0.662656894085997 SLC22A23 other 1 1 1 1.28476068059712 -0.436547147190848 0.229402158680253 1170.0014187272 683.299118263585 1.71228293357152 0.0875588524520361 1192.12928041452 1179.15054368181 1.01100685302843 0.312576461363428 TUBB2A other 1 1 1 1.71228293357152 1.01100685302843 0.000140481716774547 82.5131388329141 53.9555052626107 1.52928118143475 0.126923253206542 -353.6197269224 121.030806172791 -2.92173321904137 0.00366262285894072 LRRC1 other 0.683303070391395 1 1 1.52928118143475 -2.92173321904137 0.000391625379271655 -29.3492806023136 19.9268212911155 -1.47285310454404 0.141518844734514 -134.549493974381 34.1333677522333 -3.94187573142639 9.42836608457312e-05 FOXF2 other 1 0.752289329888089 1 -1.47285310454404 -3.94187573142639 2.82743813382726e-10 154.209059586543 27.5381547190087 5.59983271065352 3.8128817954787e-08 -20.2586137008511 47.5218381540293 -0.426301138335353 0.670099785975351 BPHL other 2.05272008515859e-06 1 0.000351357057453362 5.59983271065352 -0.426301138335353 0.00942392307301338 134.919537900285 44.4457037073176 3.03560359374109 0.00254501743277132 89.4381399693348 76.6987316242776 1.16609672774595 0.244215745260724 RIPK1 other 1 1 1 3.03560359374109 1.16609672774595 0.0183657541754812 3068.41021483584 1080.37558868799 2.84013286394422 0.00472154600974406 2651.39603637581 1864.37451583331 1.42213702979668 0.155704741788923 TUBB2B other 1 1 1 2.84013286394422 1.42213702979668 3.62080564820869e-08 236.632988422883 59.9884174490876 3.94464462450129 9.30462322342126e-05 -371.282904315621 140.839256458825 -2.63621744143593 0.00868137758585578 UQCC2 other 0.000239443877516041 1 0.774330744653117 3.94464462450129 -2.63621744143593 0.000179220945158094 763.964759764212 188.072691960093 4.06207170111819 5.76357892794704e-05 257.137412888908 441.552206613044 0.582348834492975 0.560631381108233 HMGA1 other 0.859005990142743 1 0.484832259418905 4.06207170111819 0.582348834492975 0.0147552882461054 90.7700801756823 43.8258180716054 2.07115540952085 0.0389293379358132 261.202398463376 96.9559339162575 2.69403210214015 0.00733056048589593 TCF19 other 1 1 1 2.07115540952085 2.69403210214015 3.67237759797598e-07 1313.41506575487 247.977760443788 5.29650345823088 1.87262155561406e-07 303.75283685278 544.763105336646 0.557587020628114 0.577411270812336 FLOT1 other 0.00228825848129883 1 0.00170595823716441 5.29650345823088 0.557587020628114 0.203744181232289 107.542640715413 60.8947037721382 1.76604259572108 0.0780852795904093 124.965356579243 133.774850882182 0.93414685761304 0.350742836246235 IER3 other 1 1 1 1.76604259572108 0.93414685761304 2.22449764492805e-07 229.522335612838 73.5888104379685 3.11898418043206 0.00193452420491924 -504.596377846242 161.661549085991 -3.12131351393793 0.00191962021549661 MDC1 other 0.00140588251159453 1 1 3.11898418043206 -3.12131351393793 1.44111974807129e-05 81.0472862964803 22.705502604754 3.56949976872614 0.000397219026857518 -60.7067713652955 46.2010926277474 -1.31396830491486 0.1895446231474 PGBD1 other 0.0788724838119419 1 1 3.56949976872614 -1.31396830491486 1.8851652069526e-07 285.39103629669 172.447624265521 1.65494327632643 0.0986523295896093 -1650.66100548583 378.836808327848 -4.35718221988961 1.64296488214439e-05 ATAT1 other 0.00119557177424934 0.137516160635486 1 1.65494327632643 -4.35718221988961 0.0119397455543327 88.2232614489935 30.8520558778739 2.85955859143456 0.00444546301890487 33.4209756885544 58.8082565665449 0.56830414026535 0.57012036739181 TPMT other 1 1 1 2.85955859143456 0.56830414026535 0.709354024145368 15.7569340117913 28.1273366643473 0.560200000441703 0.575630084819134 43.0326010284566 53.6145674582679 0.802628894879213 0.422625549477181 RNF144B other 1 1 1 0.560200000441703 0.802628894879213 7.9845928944841e-07 195.139042609154 36.409514795878 5.35956174376831 1.35176635545225e-07 126.907266852032 79.9852386298939 1.5866335967222 0.113317283767674 NRM other 0.0048721985842142 1 0.001234433035799 5.35956174376831 1.5866335967222 5.32735440800498e-05 387.294601586014 330.352201190483 1.17236876336931 0.241686283372647 -2757.31521139902 775.592362053739 -3.55510877401855 0.000418955324445459 MTCH1 other 0.273133460498415 1 1 1.17236876336931 -3.55510877401855 0.000935892552365264 435.311941083645 130.618793552274 3.33268995406417 0.000933086930382558 -93.8276846772358 286.946294956127 -0.326986918202174 0.743833986481314 VARS2 essential 1 1 1 3.33268995406417 -0.326986918202174 3.0019750769029e-05 104.811484593838 25.5549592136428 4.10141466936417 4.89629000688602e-05 -23.1119945414064 59.5643803970539 -0.388017039501507 0.69819193262046 TAF8 essential 0.158954580322009 1 0.412953099180767 4.10141466936417 -0.388017039501507 5.2891706090203e-07 128.2595378658 80.9187116424554 1.58504176923284 0.113680184224477 -603.720772762862 155.403052732832 -3.88487074189447 0.000118240722425839 FAM8A1 other 0.00326976527049635 0.933983466441702 1 1.58504176923284 -3.88487074189447 0.0320492095072487 9.90995621549593 6.60748575066537 1.49980742894497 0.134389692282479 -11.9586902722254 11.4386184800483 -1.04546631160784 0.296388095251911 C6orf52 other 1 1 1 1.49980742894497 -1.04546631160784 0.347058931582557 -3.01869303122144 23.1211954083821 -0.130559557060232 0.896183954008275 -47.211022299261 37.1672181122728 -1.27023287448225 0.204679125673118 FGFBP2 other 1 1 1 -0.130559557060232 -1.27023287448225 0.0136953356686235 -61.3460822695207 82.3300704781265 -0.745123645750057 0.456598443185952 -366.615181187061 132.345219726399 -2.77014297868088 0.00584253385601624 CPEB2 other 1 1 1 -0.745123645750057 -2.77014297868088 0.00900547154276584 -252.321281209211 133.555792397916 -1.88925749066312 0.0595206322719233 -536.484877829706 176.405597415527 -3.04120099185971 0.00249848989659243 FHDC1 other 1 1 1 -1.88925749066312 -3.04120099185971 0.0142704726141941 -12.5584291187744 111.064087204939 -0.113073716579521 0.910024156433467 -302.317369093233 146.697693173981 -2.060818834654 0.0399129052806655 TLR2 other 1 1 1 -0.113073716579521 -2.060818834654 0.00493191889469202 34.1983783181538 11.7556093447992 2.90911149861266 0.00380907582183068 13.8127998456809 15.9175232245335 0.867773186244913 0.385993693862733 MGARP other 1 1 1 2.90911149861266 0.867773186244913 0.67811285994489 -2.13228050687681 14.8719738250715 -0.143375757109131 0.886059667503039 -13.8490916265951 19.790613479412 -0.699780814829322 0.484437386012613 TTC29 other 1 1 1 -0.143375757109131 -0.699780814829322 1.93369934237334e-15 180.834369678352 75.2360465676125 2.4035602338015 0.0166528857235894 -395.993676489919 101.92336641202 -3.88520994184135 0.000118119450515247 NEK1 other 1.5662964673224e-11 0.93314365907045 1 2.4035602338015 -3.88520994184135 0.000118533710037238 9.95322264869125 81.3593359942288 0.122336576707033 0.902688703636966 -315.721415377126 109.214809036042 -2.89082971589444 0.00403378448291561 DDX60 other 0.582237583702912 1 1 0.122336576707033 -2.89082971589444 1.36460629237351e-09 92.9467513655434 34.2525039015745 2.71357538218603 0.00691928398923143 -197.469475208981 59.4259252261585 -3.32295163192608 0.000965613691701343 MAP2K5 other 9.65595412483499e-06 1 1 2.71357538218603 -3.32295163192608 0.198299159227086 -118.518459034649 83.5793349752252 -1.4180354398582 0.15689636971259 -226.16935414793 128.670169789641 -1.75774505091341 0.0794942187041582 UNC13C other 1 1 1 -1.4180354398582 -1.75774505091341 0.79576006364672 1.56973206841378 46.0007461796153 0.0341240566464852 0.972793841655934 37.6313856276901 69.5522580154683 0.541051961523966 0.588748089919379 SQOR other 1 1 1 0.0341240566464852 0.541051961523966 4.59768091046018e-07 224.851672803668 74.5883596554735 3.01456787415981 0.00272401212434225 -180.958558293989 112.784105546329 -1.60446862097652 0.109336532845827 CTDSPL2 other 0.00285102193257636 1 1 3.01456787415981 -1.60446862097652 1.65914125777998e-09 109.509078598279 90.5063922597251 1.20995960466551 0.226948486083784 -597.913378841472 140.692526718274 -4.24978776618851 2.61733173453406e-05 SLTM other 1.170358243238e-05 0.217029147427564 1 1.20995960466551 -4.24978776618851 0.901510697621405 -138.463363857857 370.396185781217 -0.373825026210294 0.708716211439306 -252.752101303092 580.772564612045 -0.435199795417213 0.663632756784319 THBS1 other 1 1 1 -0.373825026210294 -0.435199795417213 2.21631762944396e-05 -46.6120705393664 75.7714008906982 -0.615167068200379 0.538765333381418 -452.999399383508 114.554946796898 -3.95442896225738 8.95076285074303e-05 MAPKBP1 other 0.118816788114491 0.715344967031383 1 -0.615167068200379 -3.95442896225738 0.0141642201220647 448.003601000093 152.838959269921 2.93121337085852 0.00355397792803284 446.616231806562 235.477165033509 1.89664348873492 0.0585356916627984 NUSAP1 other 1 1 1 2.93121337085852 1.89664348873492 2.64992987358738e-13 21.7650418552258 29.7161238162421 0.732432062466018 0.464298441054083 -258.482790007083 45.7832781998703 -5.6457903446463 2.96760058123909e-08 NDUFAF1 other 2.06774028036023e-09 0.000272188325311249 1 0.732432062466018 -5.6457903446463 0.00912880143624766 120.420541992336 41.8902668040135 2.87466638863229 0.00424202442855462 53.6513866674731 72.6769601998266 0.738217263352205 0.460778682283106 KIF23 essential 1 1 1 2.87466638863229 0.738217263352205 0.612346400832324 18.5138063192203 20.9034946523404 0.885679960558531 0.376277101797918 5.19540091136812 36.2662395060201 0.143257227165935 0.886153067191522 ITGA11 other 1 1 1 0.885679960558531 0.143257227165935 0.0271815751889681 142.501710349384 53.199354269223 2.67863609073587 0.00767108361100756 117.057335039753 82.8096569354594 1.4135710661256 0.158199814989549 KNL1 other 1 1 1 2.67863609073587 1.4135710661256 1.31242587190779e-05 11.9324368479175 41.4151297718528 0.288117818624517 0.77339346432938 -219.326159947721 62.6188927542327 -3.50255570325292 0.000508389272404115 HAUS2 other 0.0720653046264565 1 1 0.288117818624517 -3.50255570325292 1.05194809532849e-10 66.0323464241712 116.382386819915 0.56737405228118 0.570752085778377 -905.445665004597 179.308957867134 -5.04963988288594 6.51735312147239e-07 RTF1 essential 7.73707824114101e-07 0.0057834991599946 1 0.56737405228118 -5.04963988288594 0.000530448333255982 28.1501946464714 114.813491486833 0.24518194057098 0.806430653886208 -610.267736970755 199.194137154367 -3.06368322727201 0.00232153850077074 PARP6 other 1 1 1 0.24518194057098 -3.06368322727201 3.01682354455681e-09 5419.51987204631 1129.84147564837 4.79670820097685 2.21647668845156e-06 -1435.91547213088 1960.20341293082 -0.732533910847527 0.464235461931761 RPLP1 essential 2.1081562929363e-05 1 0.0196823129934498 4.79670820097685 -0.732533910847527 0.0754459447146897 -19.2221383951477 9.39074418359647 -2.04692386666485 0.0412631713439742 -5.69583848869881 16.2923464887697 -0.349602096458294 0.726805749721241 PAQR5 other 1 1 1 -2.04692386666485 -0.349602096458294 4.56738254814076e-07 79.8209554274672 31.9177662778694 2.50083150345054 0.0127553088563301 -142.69248875879 55.3753032965127 -2.5768254124899 0.0102982569259981 LRRC49 other 0.00283314739461172 1 1 2.50083150345054 -2.5768254124899 2.65482881273643e-17 232.520145570907 108.515288916723 2.14274087911565 0.0326869337730831 -895.392241476441 164.073064030069 -5.45727750480936 8.12537025878144e-08 TUBGCP4 essential 2.20403888033378e-13 0.000739327439846523 1 2.14274087911565 -5.45727750480936 3.50842211246122e-16 -150.630257849908 91.6845468088175 -1.6429187152335 0.101119042918071 -1113.79241961358 142.715376376544 -7.80429164601663 4.45833431107895e-14 RMDN3 other 2.87480107895073e-12 4.31343844596888e-10 1 -1.6429187152335 -7.80429164601663 0.105652602802622 -70.0092983169742 60.7791027482124 -1.15186462371778 0.250007921136157 -197.956130944424 93.6416400425338 -2.11397547986674 0.0350845897701809 ITPKA other 1 1 1 -1.15186462371778 -2.11397547986674 0.568830672196752 3.93084014847795 135.922384066396 0.028919741038075 0.976941803441232 -201.432371669128 235.816729057276 -0.85419033871937 0.393467538845588 UACA other 1 1 1 0.028919741038075 -0.85419033871937 0.0466417108877156 4.49299478793123 19.636808689361 0.228804733956872 0.819127722529872 -66.5437925373373 34.6693449654755 -1.91938418806594 0.0555866035974998 SMAD6 other 1 1 1 0.228804733956872 -1.91938418806594 0.646100655967917 52.4316396780746 134.842871940672 0.388835085781497 0.697587527168535 -88.0800446039007 207.946995249597 -0.42356969139265 0.672088057294303 PLCB2 other 1 1 1 0.388835085781497 -0.42356969139265 1.44413923261122e-11 30.9005847623776 19.9345135193286 1.55010478346593 0.121841903204493 -134.808617076413 30.1406073348347 -4.47265762029319 9.86712135576674e-06 TMEM62 other 1.08527063330733e-07 0.0836435877328347 1 1.55010478346593 -4.47265762029319 0.000284781211991561 63.9637986094042 116.156545002162 0.550668915025096 0.582142689420707 -498.432916083695 178.809977017267 -2.78750058804361 0.00554378839452601 ADAM10 other 1 1 1 0.550668915025096 -2.78750058804361 0.13821470785737 11.5101854564304 39.2935857678515 0.292927846403054 0.769716664467093 -78.9757194041958 59.4111583539838 -1.32930785381497 0.184441557807001 DUOX1 other 1 1 1 0.292927846403054 -1.32930785381497 0.961415239735743 -17.0172207117439 92.9197764203358 -0.183138846942163 0.854774207250933 -44.9981206206109 161.217631734381 -0.279114139914602 0.780289576799722 STRA6 other 1 1 1 -0.183138846942163 -0.279114139914602 0.535293779324888 8.47117351074763 8.3728674650956 1.01174102493105 0.312223025914841 12.9816735832796 12.8999772263566 1.00633306210465 0.314813541958094 CYP19A1 other 1 1 1 1.01174102493105 1.00633306210465 0.0228089194039575 58.639833284388 213.779545768823 0.274300485921137 0.783983923510906 -626.355851989067 323.253319485862 -1.93766255203595 0.0533112829040899 SEMA6D other 1 1 1 0.274300485921137 -1.93766255203595 7.05629890108054e-12 204.204403942102 116.59799475211 1.75135433826496 0.0805880418914183 -782.103583357392 177.831692816579 -4.39799886606307 1.37462930442408e-05 RSL24D1 essential 5.33103381976635e-08 0.115537593036844 1 1.75135433826496 -4.39799886606307 0.75967268137184 5.83693659130299 19.1001567076354 0.30559626712223 0.760057911847201 20.6200822871049 28.8765604137615 0.71407681495467 0.475561777106031 SPTBN5 other 1 1 1 0.30559626712223 0.71407681495467 0.482288273575262 -16.87027294817 25.4935121552436 -0.661747696646813 0.508481710618485 -47.7814085022054 39.6829815822973 -1.20407808579386 0.229211171728437 GCHFR other 1 1 1 -0.661747696646813 -1.20407808579386 1.04220810609677e-05 -42.4033133639975 57.3980659134781 -0.738758574686406 0.460450195908298 -237.083156734761 74.0865681564326 -3.20008285758579 0.00147400328862442 BCAR3 other 0.057800861564127 1 1 -0.738758574686406 -3.20008285758579 0.488896037599828 150.005221228852 152.647401987958 0.982690954941283 0.326302058908189 235.627169037283 196.957412736416 1.19633562283141 0.232212801338247 TTLL7 other 1 1 1 0.982690954941283 1.19633562283141 1.04481660522323e-66 146.102396752552 92.9176994078055 1.57238499966863 0.116584992477227 -1186.9435025854 119.933544110914 -9.89667662524601 5.69635666735938e-21 FNBP1L other 1.0175468918269e-62 5.59325261168018e-17 1 1.57238499966863 -9.89667662524601 7.10227982399308e-24 37.1908839139879 28.869770584102 1.2882292848724 0.198346270880284 -178.075174299951 37.2499973565694 -4.78054193119415 2.39107633688584e-06 KYAT3 other 6.24787556116671e-20 0.0207999730545699 1 1.2882292848724 -4.78054193119415 1.66464937062904e-65 78.8933731486565 21.2961576643284 3.70458250695639 0.000238826133254115 -214.726566627645 27.4779397498282 -7.8145075133949 4.13476524698621e-14 GTF2B essential 1.62020323243325e-61 4.00121232950856e-10 1 3.70458250695639 -7.8145075133949 8.93236428594989e-27 104.225136820088 58.5037789053509 1.78151119073362 0.0755217803574636 -354.519749644243 75.1289482786534 -4.71881688439626 3.19619898343296e-06 RABGGTB essential 7.98017425306763e-23 0.0276503174056786 1 1.78151119073362 -4.71881688439626 4.61518907736876e-07 -174.372787585393 757.240505147001 -0.230273983496885 0.817986384947388 -3049.15888852432 972.427487765018 -3.13561569051525 0.00183040459363735 IFI44L other 0.00286095570906089 1 1 -0.230273983496885 -3.13561569051525 1.07829450899743e-07 0.257349507547081 2.95734958975597 0.0870203199643761 0.930695310739204 -11.5068918556607 3.80138267422435 -3.02702801632793 0.00261609609396409 GIPC2 other 0.000692696392579947 1 1 0.0870203199643761 -3.02702801632793 0.00350941072899349 -24.1378339711299 50.7385963634692 -0.475729241664807 0.634504463478043 -144.0739818832 65.4632255356166 -2.20083842041688 0.0282685826425269 ARHGAP29 other 1 1 1 -0.475729241664807 -2.20083842041688 1.18221565384672e-08 207.289647119103 110.122147606897 1.8823611019562 0.0604496591681251 -220.603054171807 141.415841620722 -1.55995998498857 0.119491557095798 IFI44 other 8.04734195573465e-05 1 1 1.8823611019562 -1.55995998498857 4.85091955597928e-22 269.293950437703 62.3447119880845 4.31943531135683 1.93694772795093e-05 -118.171646701492 80.0613691976732 -1.47601331185985 0.140658847646128 SLC44A5 other 4.22369565739116e-18 1 0.166209484535469 4.31943531135683 -1.47601331185985 9.31334945526674e-41 32.4143393856231 40.0950532265883 0.808437370127448 0.419277724062896 -384.783380742704 51.7308656595883 -7.43817788155231 5.4319108082098e-13 DBT other 8.71263841540204e-37 5.22767096182111e-09 1 0.808437370127448 -7.43817788155231 1.25800061437123e-48 62.5860444558195 26.4481725582431 2.36636555202425 0.0183979789057021 -239.212887680929 34.1235826230254 -7.01019263784796 9.05239729667595e-12 RTCA other 1.19774238494285e-44 8.64232369913653e-08 1 2.36636555202425 -7.01019263784796 2.67571736711757e-43 663.015408455126 212.892151415354 3.11432527712859 0.00196465405147381 -1532.57028759446 256.083491085604 -5.98465086951722 4.5152440204839e-09 ACTR1A essential 2.51945547287791e-39 4.1905979754111e-05 1 3.11432527712859 -5.98465086951722 2.84721809068781e-31 49.6175314524454 22.7280278479224 2.18309884977464 0.0295587186413227 -143.404489012976 27.3390666499086 -5.24540544303679 2.43301107941035e-07 MFSD13A other 2.58869068805336e-27 0.00218630375595814 1 2.18309884977464 -5.24540544303679 2.36285565721131e-08 -100.285364602421 176.66713627474 -0.567651498275629 0.570563140033215 611.765874679368 211.815744167317 2.88819831162372 0.00406703873112784 MYOF other 0.000158193186250297 1 1 -0.567651498275629 2.88819831162372 1.00694144280582e-14 -10.8761055769239 13.3452444074804 -0.814979871843151 0.415526743064497 64.0193045772808 16.093515171339 3.97795658038046 8.13218274237414e-05 LOXL4 other 8.05553154244655e-11 0.651550481319016 1 -0.814979871843151 3.97795658038046 1.48979576648016e-11 93.3029797623764 28.3778569676216 3.28787969679432 0.00109097760410513 -32.8834975383562 34.3186515597516 -0.95818151482739 0.338501038767717 STAMBPL1 other 1.1191345797799e-07 1 1 3.28787969679432 -0.95818151482739 0.023317268492523 67.6473288742978 154.760722428338 0.43710915672174 0.662248104859531 -220.57519902336 187.159281062466 -1.17854267109384 0.239221654038809 CH25H other 1 1 1 0.43710915672174 -1.17854267109384 2.45897644731587e-36 -77.7133989956635 113.779713881785 -0.683016298286762 0.494959306621049 -1175.3672765936 137.617322844644 -8.54083811760001 2.24741893763153e-16 ATAD1 other 2.27455321376718e-32 2.19168294797827e-12 1 -0.683016298286762 -8.54083811760001 0.881253616416808 -2.91684730279065 13.6126097522021 -0.214275392881132 0.830432252627782 -6.62512747297593 15.8152156193044 -0.418908450725715 0.675488859405003 BTBD16 other 1 1 1 -0.214275392881132 -0.418908450725715 2.06094810569047e-05 272.673237570805 84.6979384560006 3.21936097314169 0.00138032556683547 469.609609770769 102.275838605244 4.59159872140802 5.75593172861054e-06 KIF11 essential 0.110920227048261 0.0492937993238207 1 3.21936097314169 4.59159872140802 4.95992173864707e-08 41.8387682498125 8.61094956882827 4.85878681734119 1.64768070197225e-06 24.2168582699055 9.99638252334828 2.42256218320406 0.0158162077710426 CUZD1 other 0.000325420465272635 1 0.0146956641808905 4.85878681734119 2.42256218320406 1.03441664771707e-12 182.834562607613 136.508744964025 1.33936153801572 0.181149170072465 -438.575718947583 158.596718397619 -2.76535178898233 0.00592696441903875 TACC2 other 7.962939354126e-09 1 1 1.33936153801572 -2.76535178898233 0.373472292596123 -19.3888336315563 81.8318526488157 -0.23693504428849 0.812818209513001 52.9544468546629 97.4887328145685 0.54318530281224 0.587279176147984 DUSP5 other 1 1 1 -0.23693504428849 0.54318530281224 0.000702145226958301 20.1387493504216 32.8567781471026 0.612925261882303 0.54024459925044 101.842343406346 39.34456416066 2.58847303506735 0.00996158511712479 CALHM2 other 1 1 1 0.612925261882303 2.58847303506735 1.62512740018395e-61 104.181603579749 111.103539333238 0.937698332609121 0.348917404653211 -1341.86861278704 132.709342696319 -10.1113349333487 9.75813762957973e-22 ARL3 other 1.57556101447834e-57 9.58639440729913e-18 1 0.937698332609121 -10.1113349333487 1.22159885832929e-15 39.4832392817874 22.2097612173553 1.77774262835992 0.0761414662584861 164.658419934041 26.6284788400975 6.18354585415134 1.44036168994837e-09 CEP55 essential 9.92671232278377e-12 1.34616203542575e-05 1 1.77774262835992 6.18354585415134 0.000314338932984233 71.1382932994034 22.385799557967 3.17783124588399 0.00158912890095934 109.484877662958 27.0721801083451 4.04418400087434 6.20679778586928e-05 KIF20B other 1 0.501385125142521 1 3.17783124588399 4.04418400087434 0.000474134365366896 -7.03192800294116 47.0941700149928 -0.149316316663028 0.881372766913738 135.508094950379 59.5047073991632 2.27726680582391 0.0232516315462355 ENTPD1 other 1 1 1 -0.149316316663028 2.27726680582391 2.73191997075736e-12 38.2490854227631 32.0076303583819 1.19499897351029 0.23273704389988 -121.069212442072 38.3806450543822 -3.1544340192961 0.00171935692935021 EXOC6 other 2.08527451367909e-08 1 1 1.19499897351029 -3.1544340192961 2.17770671226996e-08 137.31803591058 131.2328087584 1.04636970899086 0.295968783933614 660.823003297904 157.342082021976 4.19991266675629 3.23779093872668e-05 PLCE1 other 0.000146124120393314 0.266923484988628 1 1.04636970899086 4.19991266675629 0.238422287059935 -27.0523930190228 32.9326363060681 -0.821446323568033 0.411841027668515 -59.789386963608 39.5421611327267 -1.51204145779791 0.13124777096535 RBP4 other 1 1 1 -0.821446323568033 -1.51204145779791 0.000100597692305115 28.9128834068098 20.4032209102679 1.41707446750525 0.157172049330909 -143.714309164244 44.5605484596167 -3.22514677516785 0.00135336930966621 DBR1 essential 0.498964553833371 1 1 1.41707446750525 -3.22514677516785 0.00380884369609543 24.4170197740123 76.9498814457146 0.317310687362626 0.751159416097774 -473.354006163328 162.234906774652 -2.91770751174301 0.0037080289382503 DNAJC13 other 1 1 1 0.317310687362626 -2.91770751174301 6.98831540496602e-23 -135.676198327643 139.812297626187 -0.970416770421708 0.33237436229146 -1203.19664939348 169.493901393482 -7.09876071942108 5.10980698786455e-12 ANXA7 other 6.11407714780477e-19 4.88804136459123e-08 1 -0.970416770421708 -7.09876071942108 3.0139839296751e-43 103.293269344012 42.5469056233306 2.42775045166553 0.0155947999658918 -372.872335413968 51.579447221443 -7.22908746604317 2.18104251819143e-12 FAM149B1 other 2.83736447139614e-39 2.09205598344922e-08 1 2.42775045166553 -7.22908746604317 3.9285813322906e-42 120.276853679168 70.9540154271205 1.69513808281519 0.0907599501119822 -669.687410032768 86.1516993296812 -7.77335113809004 5.50473504487356e-14 ASCC1 other 3.68815215475442e-38 5.32307878839273e-10 1 1.69513808281519 -7.77335113809004 0.000969412970107606 -179.700482237679 143.941389275439 -1.24842814941721 0.212541207529275 -592.574204246859 185.373046445407 -3.19665785080236 0.001490971382068 ZNF365 other 1 1 1 -1.24842814941721 -3.19665785080236 0.152893759187374 -15.9351564702568 67.0605991649634 -0.237623234338507 0.812284439742619 77.7775853504635 81.4243498602607 0.955212850749736 0.339996958262654 ADAMTS14 other 1 1 1 -0.237623234338507 0.955212850749736 1.62678497811892e-20 3655.38682097303 1242.66613514518 2.94156790596532 0.00343914744526074 -5010.09699013942 1506.67221023175 -3.32527337805532 0.000957806387671113 RPS24 essential 1.39659490371509e-16 1 1 2.94156790596532 -3.32527337805532 7.09973504475605e-16 4.08655201578941 27.5284538279401 0.148448294311457 0.882057307073253 -168.83349816448 33.4247901675373 -5.05114609001956 6.45797383473913e-07 TET1 og 5.78557408797171e-12 0.00573145177833097 1 0.148448294311457 -5.05114609001956 0.000700925115821568 56.6537919368478 15.0298260810934 3.76942431876273 0.000186042235597699 47.1752624991981 18.2490737095174 2.58507709761701 0.0100579708254652 DNA2 other 1 1 1 3.76942431876273 2.58507709761701 0.000204174607330609 -59.2978635505219 96.3441597118604 -0.61547958618214 0.538557711441263 -732.356611695676 186.538451045176 -3.92603566499174 0.00010027567184951 SLC35A5 other 0.970033559427723 0.7979937965784 1 -0.61547958618214 -3.92603566499174 0.00111798418436042 -72.5799102927299 34.2481211620802 -2.11923772253793 0.0346324515734791 -244.614579117768 66.3101063093862 -3.68894867965462 0.000253513455073972 DIRC2 other 1 1 1 -2.11923772253793 -3.68894867965462 0.00124056941886737 44.1511050849869 56.9993380226914 0.774589786769286 0.439000025904701 -328.732635011784 114.2902659464 -2.87629600202308 0.00422013961129784 SENP7 other 1 1 1 0.774589786769286 -2.87629600202308 0.0226569842052858 24.3071157654331 25.0506065853849 0.97032044643639 0.332422303680781 -93.1963077592335 49.755597754488 -1.87308186345379 0.0617228883376567 COX17 essential 1 1 1 0.97032044643639 -1.87308186345379 0.539617002732186 -35.555712936733 195.386525094834 -0.181976279681905 0.855685529377785 -398.795224605426 378.30108078469 -1.05417416143307 0.292384348613021 PARP9 other 1 1 1 -0.181976279681905 -1.05417416143307 0.43855737435778 64.7734835676879 51.1014827621064 1.26754606846203 0.205636642581941 50.4045812543816 77.9384174174076 0.646723181257767 0.518151419227661 MNS1 other 1 1 1 1.26754606846203 0.646723181257767 2.64966092779639e-09 13.2698765931653 105.596307321542 0.125666104523508 0.900054025611513 -776.311798952502 159.648464524766 -4.86263241718854 1.61878595424095e-06 USP8 essential 1.85767727647805e-05 0.0141789461731965 1 0.125666104523508 -4.86263241718854 0.00122761267550345 -183.277311445117 288.565287107202 -0.635132913187265 0.525674902276719 -1396.52528336751 436.30525524131 -3.20079867613587 0.00147066507022762 SECISBP2L other 1 1 1 -0.635132913187265 -3.20079867613587 0.0522646639663034 89.7425362383093 92.9967745615252 0.96500697644021 0.335076252430589 -166.308241721708 144.573696023388 -1.15033540883401 0.250636283396501 TMOD3 other 1 1 1 0.96500697644021 -1.15033540883401 0.00717495891873506 152.904959830244 90.840274892287 1.68322872218903 0.0930450213247754 -138.158794961961 138.592203188368 -0.996872780600666 0.319377924551061 SPPL2A other 1 1 1 1.68322872218903 -0.996872780600666 0.223999405718025 19.4268491414429 41.2721770422684 0.470700857905972 0.638089225202197 -78.5435012221991 71.604613603792 -1.09690559405574 0.273286734617423 GLCE other 1 1 1 0.470700857905972 -1.09690559405574 3.54484340615361e-05 20.8069382788387 60.2844398078218 0.345146083220949 0.730150995080048 -300.032685850779 91.1489325729597 -3.2916752547883 0.00107690519530132 SHF other 0.185891588218695 1 1 0.345146083220949 -3.2916752547883 0.000676571802815944 78.5267483815529 65.8182978111436 1.193083853473 0.23348388263648 -239.802881296321 109.151245908467 -2.19697795751611 0.0285463186234583 APH1B other 1 1 1 1.193083853473 -2.19697795751611 7.32964156903397e-12 113.699509689468 44.1465491977022 2.57550163615927 0.0103386728276131 -315.483819752513 75.8700728128563 -4.15821163808154 3.86510116705295e-05 INTS14 other 5.53681124124826e-08 0.316938295698342 1 2.57550163615927 -4.15821163808154 0.875611460625388 7.50035022180706 21.808168437532 0.343923894539392 0.731069703093472 -4.31155731963588 37.4794260783742 -0.115037976051711 0.908468102625442 CILP other 1 1 1 0.343923894539392 -0.115037976051711 1.31747859583579e-06 22.8979687135181 14.3395489225626 1.59684023794425 0.111027478399153 -78.6829675461132 24.6438881550219 -3.19279843550497 0.00151129128500817 PARP16 other 0.00790355409641888 1 1 1.59684023794425 -3.19279843550497 1.15246449665749e-05 19.3811494984876 12.7262104352288 1.5229317161719 0.128502397693046 -63.7019203796784 22.0812844011138 -2.88488292721166 0.0041101935273779 PPCDC other 0.0636506141503932 1 1 1.5229317161719 -2.88488292721166 0.0336484610380755 -37.5451836315897 16.4128751366371 -2.28754458429898 0.0226410719075518 -7.77609620665689 28.4752990151835 -0.273082161578375 0.784919062694942 HCN4 other 1 1 1 -2.28754458429898 -0.273082161578375 0.363807038950166 -267.399857817575 221.756610568818 -1.20582586977533 0.228538599419237 -504.543537695359 384.752061989723 -1.31134719612974 0.190430646824567 SEMA7A other 1 1 1 -1.20582586977533 -1.31134719612974 7.19418108319905e-07 116.392574749766 75.4819565769045 1.54199202071795 0.123800983543591 -440.380568654067 130.962672821743 -3.36264188234369 0.000840110343208168 UBL7 other 0.00440355824102614 1 1 1.54199202071795 -3.36264188234369 8.41500157938275e-05 -78.706239431344 72.0395795100548 -1.09254162734749 0.275195658874897 -394.301830719228 102.832763529306 -3.83439885486359 0.000144329152309798 ARHGAP24 other 0.420413478905962 1 1 -1.09254162734749 -3.83439885486359 2.21921065013915e-06 41.1676496767727 104.775933225504 0.392911314740282 0.694576139087266 -538.602537244997 152.323420360807 -3.5359141487843 0.000449684856151875 FAM13A other 0.0131044388890717 1 1 0.392911314740282 -3.5359141487843 0.0238189147575293 -157.828695503631 170.239429582577 -0.927098357240877 0.354386038888435 -626.1598365446 247.494356728658 -2.52999642020563 0.0117558722532436 HERC6 other 1 1 1 -0.927098357240877 -2.52999642020563 0.0118399954931499 48.6088039344379 84.9872418106974 0.571954129805863 0.567646464899372 -219.459796984436 123.55458893193 -1.77621728890494 0.076391230362418 HERC5 other 1 1 1 0.571954129805863 -1.77621728890494 5.78672283627619e-05 224.332781254678 275.392695296138 0.814592344264783 0.415749379208517 -1023.05398212173 376.246451966785 -2.71910599229265 0.00680656790797307 PCDH10 other 0.295643669705351 1 1 0.814592344264783 -2.71910599229265 0.557906270677694 -14.1951802967959 14.212791072219 -0.998760920685207 0.318464494155562 -19.0510680317658 19.9291425734259 -0.955940174624926 0.339632185377281 NDST4 other 1 1 1 -0.998760920685207 -0.955940174624926 2.20137130315569e-05 93.4149802890931 19.9997211141687 4.67081414564896 3.99681647859e-06 75.4494649896757 28.1141820325524 2.68367989160472 0.00755756557929947 ZGRF1 other 0.118081556701271 1 0.0352399308917281 4.67081414564896 2.68367989160472 2.8957823894634e-07 29.1286465177405 35.0448836799985 0.831181144264016 0.406324177297695 -182.422451661348 49.2635989004418 -3.70298670281907 0.000240287777603207 AP1AR other 0.00181797218410512 1 1 0.831181144264016 -3.70298670281907 1.34492559070615e-10 53.3682430633846 50.7263860080763 1.05208052974418 0.293342677676058 -324.443170323529 74.2643939431144 -4.368758069608 1.56171172131822e-05 COPS4 essential 9.86368428223892e-07 0.130840208012041 1 1.05208052974418 -4.368758069608 7.36206824090422e-12 1078.28959644047 244.106169038741 4.41729760737566 1.2616286899605e-05 -533.366696170121 360.048610375502 -1.48137412782641 0.139227567088409 HNRNPD other 5.56057014235496e-08 1 0.109181346829182 4.41729760737566 -1.48137412782641 0.0989994010099811 -63.8752119145249 29.7118544386738 -2.14982245710598 0.0321187416091531 -67.8524483519953 43.4499611769276 -1.5616227613116 0.11910240322066 PRKG2 other 1 1 1 -2.14982245710598 -1.5616227613116 0.121629947358496 10.5532644693267 53.2943046373733 0.198018616456928 0.843122789529856 -108.424144456711 77.9364166657711 -1.39118718944554 0.164878145424983 RASGEF1B other 1 1 1 0.198018616456928 -1.39118718944554 0.0157491914532242 127.571993361402 208.701431689211 0.611265540101214 0.541340905356266 -516.101030278765 305.542865541258 -1.68912806837925 0.0919065625747879 SEC31A other 1 1 1 0.611265540101214 -1.68912806837925 0.661897129047882 -2.1685264127827 8.61434327082836 -0.251734385849959 0.801364447300113 -9.93633491631151 12.2965282495259 -0.808060186963308 0.419494580141261 GPAT3 other 1 1 1 -0.251734385849959 -0.808060186963308 5.10730404602417e-11 1.87847222222329 143.326306296023 0.0131062627006066 0.989548995941047 -1092.19598765431 201.496468653595 -5.42042247664386 9.85074001241482e-08 FGF2 other 3.78910887174533e-07 0.000893954656126645 1 0.0131062627006066 -5.42042247664386 0.000204696697324162 50.9832270480359 28.29719462773 1.80170606022106 0.0722823380997202 -68.5611637296711 39.7855275369005 -1.72326893657704 0.0855488840562696 BBS7 other 0.97230931228977 1 1 1.80170606022106 -1.72326893657704 2.8447612134621e-06 149.580166786156 230.71028259326 0.648346337687361 0.517102272334472 -1131.31632768575 324.375982210099 -3.48766983294403 0.000536726567607454 KIAA1109 other 0.0166333188151129 1 1 0.648346337687361 -3.48766983294403 5.75604662759324e-08 144.363423033002 145.488815449014 0.992264749612962 0.321616237657321 -761.284981523608 211.511874065004 -3.59925410754785 0.000355587345518169 BMPR1B ts 0.000375812284315563 1 1 0.992264749612962 -3.59925410754785 0.0044906171565091 -19.3534788432751 120.782701141805 -0.160233863461566 0.872770724845139 -439.240682373336 171.666744419885 -2.55868242773326 0.0108421689483592 RAP1GDS1 og 1 1 1 -0.160233863461566 -2.55868242773326 1.68301935518851e-07 47.2484888304865 20.7017797525186 2.28233946043882 0.0229479709978967 -73.6981603153744 29.101086012034 -2.5324883162401 0.0116738665509636 LARP1B other 0.00107107351764197 1 1 2.28233946043882 -2.5324883162401 0.39635445389865 10.266166844622 20.3582199761903 0.504276250901535 0.614321998176313 -17.1176129241911 29.3524137945998 -0.583175647630737 0.560076579069488 MMRN1 other 1 1 1 0.504276250901535 -0.583175647630737 0.0677350590094669 71.4100991313648 31.4379988871686 2.27145816079633 0.0236047558095057 80.8315597855129 43.4560014765025 1.86007817192339 0.0635461014963004 PDE5A other 1 1 1 2.27145816079633 1.86007817192339 0.000283819907421039 28.793329603983 28.1784271863039 1.02182174376212 0.307430603859503 -92.690935745837 39.284741373929 -2.35946406935876 0.0187402860754952 PRDM5 other 1 1 1 1.02182174376212 -2.35946406935876 0.386390076889955 -19.9282857250671 19.0073175155249 -1.04845335007372 0.295010617365849 0.447337836308058 26.7240680344853 0.0167391370105331 0.986652381778572 TRPC3 other 1 1 1 -1.04845335007372 0.0167391370105331 0.058912998398989 -27.3361026447739 27.099237766022 -1.00874064727566 0.313657238069461 -90.501622259365 39.6261969696714 -2.28388362195424 0.0228573197803867 NAAA other 1 1 1 -1.00874064727566 -2.28388362195424 1.25087193870265e-11 134.740045226627 35.5173988994031 3.79363493391661 0.000169370851341197 -109.028020843575 51.9357576323719 -2.0992862300254 0.0363647181138109 NUP54 essential 9.41156046679874e-08 1 1 3.79363493391661 -2.0992862300254 0.669162938958317 41.0842591682243 45.8281725977808 0.89648477867114 0.370487483181677 41.274210992037 67.012814522655 0.615915198996507 0.538271151158123 CXCL9 other 1 1 1 0.89648477867114 0.615915198996507 1.00277696875435e-07 -188.316001211235 186.140696128284 -1.01168634870395 0.312249146124527 -1251.47427758791 260.932726519308 -4.79615682663442 2.22384294628126e-06 BMP2K other 0.000646791144846554 0.0193696720621098 1 -1.01168634870395 -4.79615682663442 0.0489827887680952 -241.372894883035 299.839112188466 -0.805008036214163 0.421251803390136 -950.37893279014 424.153291433558 -2.24064967073116 0.0255492898798338 G3BP2 other 1 1 1 -0.805008036214163 -2.24064967073116 6.19828554407367e-05 59.5890569042647 369.686355533773 0.161188142359831 0.872019710816603 -1703.55197588973 536.662217572031 -3.17434676806008 0.00160789152429656 SEPT11 other 0.315306785627028 1 1 0.161188142359831 -3.17434676806008 0.82883019706254 -4.9933477346528 40.5581060870829 -0.123115900035655 0.902071922284901 -30.9812592094528 58.876944813905 -0.526203581170467 0.599013711341865 FRAS1 other 1 1 1 -0.123115900035655 -0.526203581170467 6.19235567785595e-06 -264.340871104089 720.617978192089 -0.36682525152547 0.713926923442043 -4139.82985940419 1053.73258798924 -3.92872907850741 9.92305865324556e-05 SCARB2 other 0.0351540031831882 0.790073929971412 1 -0.36682525152547 -3.92872907850741 0.00142763618941324 148.856137012819 97.6337234996002 1.52463853346153 0.128072627733724 -200.779843397569 141.731848575957 -1.41661768624973 0.157307177893575 CCNG2 other 1 1 1 1.52463853346153 -1.41661768624973 3.3782284895275e-09 60.6248956858 62.98161404318 0.962580851678965 0.336290235080486 -366.753878103796 91.4284559133287 -4.01137560992463 7.10025052102527e-05 CNOT6L other 2.35394961150276e-05 0.571357159426904 1 0.962580851678965 -4.01137560992463 4.60606140294521e-08 29.1908614805216 82.1191014830399 0.355469810961709 0.722408780875897 -499.888686202973 120.07023302792 -4.16330237392587 3.77840144176707e-05 USO1 other 0.000302848537243647 0.310055622311405 1 0.355469810961709 -4.16330237392587 0.535359094422817 -17.3287933836014 17.840568588418 -0.97131396332576 0.331928035893407 -27.0583499169299 25.2373208838321 -1.07215619445027 0.284240262652806 CDKL2 other 1 1 1 -0.97131396332576 -1.07215619445027 0.397288769722414 56.371699498816 88.1798964416284 0.639280627145347 0.522975340426779 -58.2127032040536 128.008021019085 -0.454758246714668 0.649508990924071 SHROOM3 other 1 1 1 0.639280627145347 -0.454758246714668 0.237511200700326 -16.4997854107958 16.5020077659276 -0.999865328197434 0.317929002879765 -40.4348793293377 23.9554529116088 -1.68791963477104 0.0921401449597599 ANXA3 other 1 1 1 -0.999865328197434 -1.68791963477104 4.87382052010919e-14 155.066364630897 41.2611999979304 3.75816419877937 0.000194394353684084 -181.448439878235 57.8511896729347 -3.1364685999383 0.00182547554266169 PPA2 essential 3.85714155961441e-10 1 1 3.75816419877937 -3.1364685999383 7.82025573345948e-07 209.25270790873 39.186899117983 5.33986389886876 1.49714881706254e-07 231.345557981402 57.0573061886585 4.05461760175749 5.94356523536765e-05 CENPE essential 0.00477661220199705 0.480893863193597 0.00136599858068786 5.33986389886876 4.05461760175749 9.86027059794622e-06 45.2262612569767 21.9959285718351 2.05611966365844 0.0403643760394134 -64.2279934043626 30.83988434426 -2.08262757043435 0.03786618186326 GSTCD other 0.0548625456069727 1 1 2.05611966365844 -2.08262757043435 1.44742718855965e-12 61.7104380707743 32.892264395243 1.87613833238246 0.0613025861370185 -207.006278538815 46.1173360541371 -4.48868682041413 9.17852477079525e-06 INTS12 essential 1.11046613906297e-08 0.0778797826801977 1 1.87613833238246 -4.48868682041413 0.591181211739932 19.2018396846256 33.2183007498198 0.578050028183027 0.563527407437874 47.6785057255494 46.6959188461327 1.02104224317021 0.307798042326613 ENPEP other 1 1 1 0.578050028183027 1.02104224317021 3.77616461494124e-05 49.1446780551904 15.3337086085964 3.20500925833682 0.00144934996439129 -9.48730993054272 21.555034322493 -0.440143577996652 0.660050237467116 CASP6 other 0.197380124422978 1 1 3.20500925833682 -0.440143577996652 0.282059154902304 48.4319843367242 63.2637693476497 0.765556413032849 0.444353556900796 -50.6419301325187 88.1987060786096 -0.574179966851018 0.566141444045981 LEF1 other 1 1 1 0.765556413032849 -0.574179966851018 1.35709779680119e-12 143.854140545131 66.4808992370236 2.16384167777649 0.0310176781241013 -388.920562874943 92.6838434084822 -4.19620668039053 3.28910413956826e-05 HADH other 1.04197968838395e-08 0.271087963183216 1 2.16384167777649 -4.19620668039053 0.0202460766120274 11.3277266754273 15.0243084219442 0.753959939938548 0.451278401482864 -33.5759902384082 21.1201015992421 -1.58976461740189 0.112609377945204 EGF other 1 1 1 0.753959939938548 -1.58976461740189 2.40314364903989e-05 85.4293127061599 150.208728981954 0.56873733827029 0.569826563175654 -664.845037711464 209.412364684101 -3.17481271325303 0.00160537078550943 PAPSS1 other 0.128472059477673 1 1 0.56873733827029 -3.17481271325303 2.02069421763867e-10 19.2683311432329 62.4335255520261 0.308621545441584 0.757756162571643 -443.831011826547 87.7645989303404 -5.05706192742725 6.27162368463415e-07 SEC24B other 1.47328815408036e-06 0.0055679475072182 1 0.308621545441584 -5.05706192742725 0.0014255767942403 -458.988614377161 356.9092690402 -1.28600923033317 0.199120811522924 -1703.45190932996 502.948250737873 -3.38693276461512 0.000770735274737389 PPP3CA other 1 1 1 -1.28600923033317 -3.38693276461512 0.375084838477424 78.2327864093542 57.336537316786 1.3644490942506 0.173126872076252 54.4633290797057 83.4837264268254 0.652382582939005 0.514496620525621 SLC39A8 other 1 1 1 1.3644490942506 0.652382582939005 0.327455001237089 38.6563476707858 38.8544801968815 0.994900651737156 0.320335149730274 -8.39883730894184 54.7528308830494 -0.153395489757991 0.878157208368313 MTTP other 1 1 1 0.994900651737156 -0.153395489757991 0.989959912786832 0.837413588129516 56.7810414828582 0.0147481195529379 0.988239844973442 15.6286711285285 115.679973244575 0.135102651653332 0.892592777148369 RGS3 other 1 1 1 0.0147481195529379 0.135102651653332 7.61769409351006e-08 132.085344445058 67.1422380708794 1.96724667273707 0.0497869183259306 -355.692018928364 107.595847521955 -3.30581548563746 0.00102509225044269 GUCD1 other 0.000495073939137219 1 1 1.96724667273707 -3.30581548563746 1.33842550244815e-24 155.587279474078 54.672769168154 2.84579109200682 0.00463902094879946 -604.706982999918 86.3416330648256 -7.0036546858675 9.49456247796361e-12 RNF185 other 1.18209740376221e-20 9.06255988521626e-08 1 2.84579109200682 -7.0036546858675 0.0184723033365482 -49.1173280916381 174.913109494848 -0.280809873162108 0.778989433266953 -590.488268320511 256.899244772294 -2.29852084167822 0.0220044624511178 KIAA1644 other 1 1 1 -0.280809873162108 -2.29852084167822 0.00406589359662657 2.67519571626995 73.048866975685 0.0366220015042864 0.970803161692756 270.492519665766 107.288692149618 2.52116522483612 0.0120522742905867 PARVG other 1 1 1 0.0366220015042864 2.52116522483612 0.0354797063311399 -49.5990591142414 367.423193651656 -0.134991638990719 0.892685218272238 -1254.99743394792 567.220859918932 -2.21253751867886 0.0274839814364329 KIF21A other 1 1 1 -0.134991638990719 -2.21253751867886 0.831452989382678 20.9504846987264 43.5839653909082 0.480692486578946 0.630993355165478 -2.3168599125642 67.2840875449631 -0.0344339946798854 0.972547956630586 CPNE8 other 1 1 1 0.480692486578946 -0.0344339946798854 1.82786410378119e-09 95.0063844306527 87.1819142448518 1.0897487770666 0.276436993226282 -564.247070248421 131.951642860404 -4.2761655559329 2.3467216354588e-05 ZCRB1 essential 1.2880958339346e-05 0.194848297392144 1 1.0897487770666 -4.2761655559329 1.01725044269214e-07 35.1752165568751 18.319345763051 1.92011314224012 0.0555048083949068 -82.8744412542757 27.7150785882889 -2.99022934357814 0.00294778489356988 TMEM117 other 0.000655617910315081 1 1 1.92011314224012 -2.99022934357814 0.0403596728352271 71.8684334851264 115.385048560587 0.622857418544909 0.53370994787904 -265.147990183855 174.637674005834 -1.5182748607554 0.129683414277386 PRICKLE1 other 1 1 1 0.622857418544909 -1.5182748607554 0.751659470900415 19.1518305502946 50.022622680857 0.382863383083345 0.702008074485051 -22.7140449340584 77.1716658124415 -0.29433140641622 0.768645075131515 AMIGO2 other 1 1 1 0.382863383083345 -0.29433140641622 3.17732645770997e-07 90.0454238916561 117.275679977337 0.767809863980808 0.443019621729625 -696.546878897334 177.53095006779 -3.92352363704109 0.000101496606238131 SCAF11 other 0.0019883708972349 0.806999516199381 1 0.767809863980808 -3.92352363704109 0.854518581422687 -20.0819094601957 81.1529184591484 -0.247457637278994 0.80467002818045 -68.1857252282028 123.910332826964 -0.550282802673297 0.582405933761445 COL2A1 other 1 1 1 -0.247457637278994 -0.550282802673297 0.00344209062749201 -67.0873896208479 121.530923043111 -0.552019090623134 0.581216818478326 -582.117580156675 193.515779362502 -3.00811428439759 0.0027802485942527 PPFIA2 other 1 1 1 -0.552019090623134 -3.00811428439759 6.34631316681831e-10 80.9333813771094 21.2828733127443 3.80274694059501 0.000163500680517153 -84.1490792129548 34.6432521406733 -2.42901788986949 0.0155429796566711 LLPH other 4.55538359114218e-06 1 1 3.80274694059501 -2.42901788986949 0.479020495701531 32.506163467176 30.0553673613083 1.0815427100393 0.280060535065792 6.16905939477791 48.8477963450477 0.126291457473359 0.899560110267953 LRIG3 other 1 1 1 1.0815427100393 0.126291457473359 0.000702128371322717 121.806836498465 42.3134039622044 2.87868205089967 0.00419941240891711 -38.4977465856308 71.0528224618491 -0.541818681535159 0.588233498090832 MARCH9 other 1 1 1 2.87868205089967 -0.541818681535159 0.034215221626228 4.88934426229936 150.873041104983 0.0324070107322698 0.97416223377698 524.104137392665 245.598262836697 2.13398959479267 0.0333984592701987 GLIPR1 other 1 1 1 0.0324070107322698 2.13398959479267 0.00279110136269787 -1069.43715846997 1442.99162758324 -0.741124992014744 0.459014808144353 -7442.83300806665 2348.9699314521 -3.1685518441122 0.00163929844037738 PHLDA1 other 1 1 1 -0.741124992014744 -3.1685518441122 9.21473820031295e-05 144.167383263676 45.196897083279 3.18976285026904 0.00152664275466409 -46.6203215339626 75.2961540200244 -0.619159399848819 0.536134734384768 TMEM19 other 0.458893962375585 1 1 3.18976285026904 -0.619159399848819 0.100063883752453 46.9088809069181 46.5861466693799 1.00692768689002 0.31452801380425 -76.6321587373646 77.6105861504993 -0.987393119139219 0.323997583467503 LGR5 other 1 1 1 1.00692768689002 -0.987393119139219 0.15464458734573 247.867499840592 302.156622534466 0.820327874204772 0.412477470028438 -454.994210962594 487.268414948021 -0.933765039975206 0.350941934909676 DUSP6 other 1 1 1 0.820327874204772 -0.933765039975206 0.000859719278830746 22.2428744500413 37.3918927295613 0.594858211936849 0.552246834822646 -161.124764663046 60.2994835903737 -2.67207536564655 0.00782083384088071 POC1B other 1 1 1 0.594858211936849 -2.67207536564655 0.0015636377377281 53.6552317796342 29.7088316559188 1.8060364137189 0.0716021365316797 -70.5225235504751 47.9095086167966 -1.47199429897201 0.141743849883618 TMTC3 other 1 1 1 1.8060364137189 -1.47199429897201 0.706381805476571 40.8525154626033 49.8267813529113 0.8198907164654 0.412726389171235 28.8595160029134 80.3524230849028 0.359161738936231 0.719647968322671 LUM other 1 1 1 0.8198907164654 0.359161738936231 9.58000597524374e-06 144.589147286822 45.6903554253677 3.16454415687353 0.00166152545345589 -92.0246216315978 75.7673208029039 -1.21456876997122 0.225184996361277 SNRPF essential 0.0533702132880829 1 1 3.16454415687353 -1.21456876997122 0.0413717205792954 6.27329271075537 2.68641154564144 2.33519421882081 0.0199850698582419 2.39487057720672 4.45507065635493 0.537560627414642 0.591154046369711 AMDHD1 other 1 1 1 2.33519421882081 0.537560627414642 0.00244259427822501 121.117880794703 41.7837117593411 2.89868649037926 0.00393596326022199 0.614367707351192 70.9078446595996 0.00866431225346824 0.993090919405577 NEDD1 essential 1 1 1 2.89868649037926 0.00866431225346824 0.000192106718931899 59.7385434191795 15.0951510689241 3.95746575482514 8.83861988571547e-05 27.1041963245775 26.2423580493383 1.03284149517428 0.302249329234026 SYCP3 other 0.917309582899816 1 0.736787353673242 3.95746575482514 1.03284149517428 0.0380651859492417 227.435340364951 262.713355322666 0.865716705135198 0.38712055730045 -709.930778439239 456.717385817578 -1.55442030560842 0.120808080804223 ASCL1 other 1 1 1 0.865716705135198 -1.55442030560842 0.0013086959200573 102.166070273069 28.7161873171318 3.55778673348177 0.000414924501261708 58.7623430826997 49.9220223730924 1.17708258378515 0.239803252753271 GAS2L3 other 1 1 1 3.55778673348177 1.17708258378515 0.0638494334151951 -106.892959663309 367.310310731232 -0.291015407246558 0.771177290144132 -1547.23749127965 676.357532946704 -2.28760295540549 0.0226365460785755 TMEM132B other 1 1 1 -0.291015407246558 -2.28760295540549 0.000137915051461581 256.79564754838 64.4827026960958 3.98239584898676 7.992602099414e-05 309.548683625785 119.731858578201 2.5853493573192 0.0100516405595998 SLC15A4 other 0.6716463006179 1 0.667811151338968 3.98239584898676 2.5853493573192 0.00013478579886587 53.7671096810298 22.4248210629002 2.39766058913989 0.0169198555782603 -66.4783296026862 39.272489681755 -1.69274548523391 0.0912182893545573 TDG other 0.657080769471116 1 1 2.39766058913989 -1.69274548523391 4.11734242107251e-07 87.5407407407401 26.1988369268051 3.34139797828863 0.000905182071677406 -87.5848148148132 46.4138954983034 -1.88703865242284 0.0598176804620637 RITA1 other 0.00255975178318078 1 1 3.34139797828863 -1.88703865242284 0.0987355699019925 79.5196283838854 58.3353869314211 1.36314564052465 0.173540136830434 -90.2718487457204 113.325490888044 -0.796571433649478 0.426133499808121 SDSL other 1 1 1 1.36314564052465 -0.796571433649478 0.000254604066758518 -26.922912446545 92.4010708272502 -0.291370134626244 0.770906187334978 -543.024164671698 154.561415115147 -3.51332293552791 0.000488553587747027 MMAB other 1 1 1 -0.291370134626244 -3.51332293552791 0.00551527801478993 489.976254782806 157.340425136198 3.11411548785807 0.00196602090780033 277.703926503387 263.186979827703 1.05515830108764 0.291934603008376 GLTP other 1 1 1 3.11411548785807 1.05515830108764 2.08590278962224e-05 173.085809137971 65.5469056938209 2.64064042849681 0.00857065305445273 -180.989738710533 109.641830010787 -1.65073620800315 0.0995092577862247 GIT2 other 0.112179852025884 1 1 2.64064042849681 -1.65073620800315 9.30534416174031e-11 140.207292370022 61.7843066568682 2.26930267500924 0.0237354451757544 -421.62018906144 103.348043299705 -4.07961462645944 5.36020903718606e-05 TCHP other 6.85617757837026e-07 0.435409780090623 1 2.26930267500924 -4.07961462645944 0.00100554852217846 191.641289669144 251.008954992823 0.763483875205263 0.44558591462533 -1071.85139033822 419.868503069594 -2.55282637897837 0.0110233772607459 FAM222A other 1 1 1 0.763483875205263 -2.55282637897837 0.181932173721733 10.591661039838 7.60131576788881 1.39339837513154 0.164206021959412 -2.40212387207651 12.7148972550164 -0.188922004157667 0.85024145395695 FOXN4 other 1 1 1 1.39339837513154 -0.188922004157667 4.63806901700934e-15 258.666341853704 83.7705307533315 3.08779638289945 0.00214521427133622 -298.499183012056 103.074631341636 -2.89595198281811 0.00397020179020274 NUP58 other 3.73271794488911e-11 1 1 3.08779638289945 -2.89595198281811 1.37284214379233e-14 158.750271646497 66.720315432212 2.37933934541703 0.0177731042747416 -282.580748252939 81.9507192432644 -3.44817898930356 0.000619220725803671 MTMR6 other 1.09635173603255e-10 1 1 2.37933934541703 -3.44817898930356 0.0383412060130599 -20.9733717962937 23.5893222607027 -0.889104467033929 0.374439469085736 -64.4756608874898 28.6345567953989 -2.25167308675963 0.0248422697152813 SLC46A3 other 1 1 1 -0.889104467033929 -2.25167308675963 1.4331321171021e-08 277.383132831011 320.280515693936 0.866063089195478 0.386935183995363 -1313.21417718735 389.51804040454 -3.37138217224418 0.000815035506128496 SLC7A1 other 9.72236828242068e-05 1 1 0.866063089195478 -3.37138217224418 0.00226816910361624 17.5084716838535 18.8288176207514 0.929876322374977 0.35295323186388 -34.44795094956 23.031581819288 -1.49568324137907 0.135464683679687 LNX2 other 1 1 1 0.929876322374977 -1.49568324137907 3.13707142157706e-10 -39.1494028509062 48.7327359034264 -0.80334916817493 0.422210680972009 -455.876114036214 77.6072487861049 -5.87414347456981 8.44279430134456e-09 SUOX other 2.27500419492768e-06 7.80451905216291e-05 1 -0.80334916817493 -5.87414347456981 0.337887302667241 24.3916035959305 23.3603047938366 1.04414748913576 0.296993083091197 -6.97134924826691 35.6682568773016 -0.195449675947111 0.845131566317473 CCDC65 other 1 1 1 1.04414748913576 -0.195449675947111 0.000102439530410802 171.874715909095 40.3251684340783 4.26221941738613 2.48135413312681e-05 119.753545217809 61.6175400567089 1.94349766491157 0.0525976984337788 TARBP2 other 0.50699932837573 1 0.21210615129968 4.26221941738613 1.94349766491157 0.000458693587587531 18.0858310626703 4.59313687247839 3.93757720808165 9.58620587548747e-05 14.5813136383195 7.98620632301526 1.82581228790671 0.0685655213044013 RDH16 other 1 1 0.797380604723048 3.93757720808165 1.82581228790671 0.47009904329418 1.26686390532612 56.6553815084177 0.0223608750236355 0.982170296120138 -85.6268244575925 87.4982298043393 -0.978612077627952 0.328313126953078 ACVRL1 other 1 1 1 0.0223608750236355 -0.978612077627952 0.0305635236724079 1.6103610619154 9.68271986916118 0.166312883536401 0.867987824262158 32.7776076941106 14.7963256592174 2.21525319522091 0.0272587469229663 GPR84 other 1 1 1 0.166312883536401 2.21525319522091 7.41811596146967e-05 39.7747159090914 9.04784823662287 4.39604145304911 1.38583720045616e-05 32.8139618844708 13.8252652821158 2.37347791994405 0.0180529622440489 NPFF other 0.373798863298457 1 0.119722475747408 4.39604145304911 2.37347791994405 1.22011639681034e-08 141.33205984333 57.3825937959074 2.46297789092638 0.0141643017215058 -278.467606266855 91.3822125959867 -3.04728456836561 0.0024495138547679 NABP2 other 8.30045184750073e-05 1 1 2.46297789092638 -3.04728456836561 1.10887382859835e-08 41.4059917620354 52.3078646409891 0.791582528673693 0.429034563206123 -209.151636859962 62.9737206379768 -3.32125265493415 0.000971540968096973 N4BP2L1 other 7.55475739424055e-05 1 1 0.791582528673693 -3.32125265493415 4.37580735784077e-13 -623.300231154504 332.224802650653 -1.87613996962752 0.0613038897708691 -3799.90924617953 529.070499208541 -7.18223611383356 2.98453299923429e-12 SMARCC2 other 3.39693925189179e-09 2.86067487976607e-08 1 -1.87613996962752 -7.18223611383356 0.00923034020333384 68.9175630635077 23.298540981907 2.95802055231815 0.00326503167110793 48.1882570641011 28.0948208396903 1.7152007246839 0.0870205681509522 BRCA2 ts 1 1 1 2.95802055231815 1.7152007246839 6.88876723610246e-11 118.515049871277 39.0738358285352 3.03310507807187 0.00256439039272793 -191.079578354733 59.6608488550807 -3.2027633200271 0.00146043626426067 KANSL2 essential 5.09355449437416e-07 1 1 3.03310507807187 -3.2027633200271 0.00110630493769833 143.058380681823 77.9133595968212 1.83612132017036 0.0670188915627969 -176.336615175184 119.052932506856 -1.48116145870686 0.13928419702527 CERS5 other 1 1 1 1.83612132017036 -1.48116145870686 9.13365705129006e-09 223.55710227273 96.9621786285823 2.30561137790721 0.0215998208381663 -478.288109611736 148.159850476493 -3.22818974285898 0.00133960712338557 MAP3K12 other 6.2474214230824e-05 1 1 2.30561137790721 -3.22818974285898 0.467929422703555 6.3271713781925 12.3796809457369 0.511093250781342 0.609543285873453 23.3347333694569 19.302134251663 1.20891985648926 0.227345829918516 ITGB7 other 1 1 1 0.511093250781342 1.20891985648926 0.0574886820230369 8.06204832469432 37.2945256932573 0.216172432142016 0.828954210428142 114.677020220453 56.4376481613883 2.03192414915173 0.0427657309241532 GALNT6 other 1 1 1 0.216172432142016 2.03192414915173 0.144995014845027 69.4450827597984 59.2211390999888 1.1726401047867 0.241577523547227 -54.7650932974879 92.3363358437793 -0.593104467456269 0.553417356942151 CSAD other 1 1 1 1.1726401047867 -0.593104467456269 0.000955889017840027 141.936269291073 53.391162831766 2.65842251344684 0.00813817369350721 -40.8956284168106 81.5216123106286 -0.5016538223138 0.616163107042937 LMBR1L other 1 1 1 2.65842251344684 -0.5016538223138 1.09922205217848e-06 201.449690006257 60.8893746581794 3.30845391559947 0.00101553668991438 -136.077395154457 94.937413112954 -1.43333792961639 0.152474700835796 C12orf10 other 0.00664040041721019 1 1 3.30845391559947 -1.43333792961639 0.660721070465328 95.9176704764363 112.076370865601 0.855824200370107 0.392565102262345 136.106819057403 178.482464314073 0.762578103011277 0.446127406675012 ESYT1 other 1 1 1 0.855824200370107 0.762578103011277 8.04300807825486e-07 285.359659090861 1173.92790276569 0.243081077141598 0.808056646643277 -7449.34762073868 1793.78170956936 -4.15287299507981 3.94960474376642e-05 TMBIM6 other 0.00490543062692764 0.323433132467032 1 0.243081077141598 -4.15287299507981 0.0112756990904468 27.4245361219148 114.17394436505 0.240199603109357 0.810288414573867 -420.364427455814 184.120925209161 -2.2830888285961 0.0229056071599071 ANKRD52 other 1 1 1 0.240199603109357 -2.2830888285961 2.32702608134221e-09 79.479096752176 63.2856559179013 1.25587853360139 0.209829512387782 -432.829663602152 98.6736436977839 -4.38647694948629 1.4447405668852e-05 ZNF740 other 1.63357230910223e-05 0.121170391344662 1 1.25587853360139 -4.38647694948629 3.26237005867296e-11 -1.42804262833444 78.7176231009169 -0.0181413331866445 0.985534402940311 -403.615816939932 91.3427820571652 -4.41869415239988 1.25450474926487e-05 WDFY2 other 2.43046569371135e-07 0.105704570173058 1 -0.0181413331866445 -4.41869415239988 0.200533177967529 188.550724522859 127.989732165091 1.47317070934762 0.141428218020691 78.2625685636036 148.536713081022 0.526890402650245 0.598538276040109 HNRNPA1L2 other 1 1 1 1.47317070934762 0.526890402650245 0.00224762220824729 8.43024396749498 82.2684265181591 0.102472410428735 0.918429039839278 224.897678450648 98.033797430673 2.2940831054687 0.0222625709516479 LPAR6 other 1 1 1 0.102472410428735 2.2940831054687 1.27774380633228e-23 266.476065642943 115.881546165886 2.2995556623095 0.0219451572980615 -669.441415187017 137.698047255893 -4.86166237305424 1.62753580833391e-06 ESD other 1.12249793386291e-19 0.0142539586093884 1 2.2995556623095 -4.86166237305424 4.79915051583634e-05 404.823817703923 165.96345881573 2.43923463991794 0.015118090522401 -94.4682457924069 197.510075592645 -0.478295831283277 0.632680502787075 RB1 ts 0.247348217586205 1 1 2.43923463991794 -0.478295831283277 0.674048305329958 9.89138728323698 23.247300385167 0.425485416343147 0.670691827513181 -24.8275086705202 46.3387879006734 -0.535782436168544 0.592380879374884 MORN3 other 1 1 1 0.425485416343147 -0.535782436168544 0.0294427712443674 92.3999421965327 52.4586680040029 1.76138559578909 0.0788708274332597 -114.889312138728 104.565736662497 -1.09872809015397 0.272490268174744 SETD1B other 1 1 1 1.76138559578909 -1.09872809015397 3.60878259483509e-08 196.373410404626 49.5208474129742 3.96546950755889 8.55422814010679e-05 -240.418583815026 98.7097859498381 -2.43561042607468 0.0152645901889647 VPS33A other 0.000238720968648341 1 0.713593711447708 3.96546950755889 -2.43561042607468 0.0104695711058453 221.680860429067 130.044561253784 1.70465306885425 0.0889731708715811 -410.722108459483 265.409672458484 -1.54750241260981 0.122469327038625 VPS37B other 1 1 1 1.70465306885425 -1.54750241260981 0.000621087517663876 71.2505202312144 25.4384588133458 2.80089767835441 0.00532169686362235 -65.3111907514437 50.7064187213658 -1.2880261000157 0.198416924865342 RHOF other 1 1 1 2.80089767835441 -1.2880261000157 1.58740611845007e-11 278.39942196532 51.0190073182603 5.45677849489787 8.12829441366984e-08 -214.953121387283 101.696064482921 -2.11368180745464 0.0351072296092944 DENR essential 1.19134829189677e-07 1 0.000745364597733525 5.45677849489787 -2.11368180745464 0.00275355845451363 59.7047495164333 19.0933618420501 3.12698989367828 0.00188456887280801 34.9177048931088 22.3401529812808 1.56300204937571 0.118779286495004 DIAPH3 other 1 1 1 3.12698989367828 1.56300204937571 3.9546399963495e-05 -657.231206121325 765.660510540172 -0.85838461965036 0.391157225408639 -3154.04805553365 891.584427479349 -3.53757642947023 0.000447666011017124 SLAIN1 other 0.20627402220959 1 1 -0.85838461965036 -3.53757642947023 7.48563585875729e-27 321.18577059824 76.0410698635813 4.22384602392434 2.93481124712014e-05 -346.220281341782 88.682692518034 -3.90403438947658 0.000109838539534442 RBM26 other 6.69066133055727e-23 0.869811394573245 0.250045918254636 4.22384602392434 -3.90403438947658 0.0145641221113142 -155.441026435843 88.7346789810732 -1.75175059199795 0.0805213801917521 -486.029899526268 168.627981119268 -2.88226127301201 0.00414389263368697 SRRM4 other 1 1 1 -1.75175059199795 -2.88226127301201 0.000491153235695411 -36.0072518872349 137.263242028008 -0.262322609864393 0.793196627983478 -556.657584987936 181.724201907648 -3.06320005340196 0.00232552604755112 MBNL2 other 1 1 1 -0.262322609864393 -3.06320005340196 0.751001585663476 13.289481667984 20.1598507391532 0.659205360195152 0.510111116137946 4.64844948382177 26.6866275956466 0.174186471001682 0.861799581305215 ZIC5 other 1 1 1 0.659205360195152 0.174186471001682 4.52512579687365e-20 120.049570720154 21.1377026874722 5.67940482913996 2.46926776878292e-08 -80.6486857269733 29.8520665783138 -2.70161147856883 0.00716888905833815 ABHD13 other 3.86853004374728e-16 1 0.00022818503451323 5.67940482913996 -2.70161147856883 0.254234800502155 37.3443411711918 37.3461697481101 0.999951037096157 0.317887568399615 -18.5601242090102 51.1240715934624 -0.363040807011616 0.716749936848086 RAB20 other 1 1 1 0.999951037096157 -0.363040807011616 0.00427134042644851 29.8191852616533 9.76313378754384 3.0542637139417 0.00239670800990131 12.6779474991775 13.9975846171778 0.905723940658959 0.365590382151843 GRTP1 other 1 1 1 3.0542637139417 0.905723940658959 3.56092229987326e-27 573.234971809739 70.9605763290412 8.07821753238971 6.7270416386557e-15 -168.807073941304 101.737484425002 -1.65924167375834 0.0977979291937028 CUL4A other 3.18773764284654e-23 1 6.52119416451283e-11 8.07821753238971 -1.65924167375834 0.000673777864588073 -214.96192234502 137.100532955144 -1.56791456394521 0.117628182823221 -653.154106438479 181.733145345855 -3.59402851469646 0.000362853314853133 SSTR1 other 1 1 1 -1.56791456394521 -3.59402851469646 0.136717016488952 105.331217924447 61.8635191152273 1.70263863793872 0.0893451921673113 27.6605337585493 92.2490083388192 0.299846407637853 0.764436560215717 CDH24 other 1 1 1 1.70263863793872 0.299846407637853 0.243343153440679 4.58210008550517 3.22586045421044 1.4204272474107 0.156194773024298 7.73522013584835 4.81030552733425 1.60805173224309 0.108544398724798 REM2 other 1 1 1 1.4204272474107 1.60805173224309 0.000167403012713733 -3.63662357776859 6.37502696684587 -0.570448344247217 0.568666831011748 26.2967772681241 9.45601813571223 2.78095672943032 0.00565420968882194 CBLN3 other 0.806547715254768 1 1 -0.570448344247217 2.78095672943032 1.60577172375138e-07 15.0185534544483 5.82117362802846 2.57998720088596 0.0102051276303616 -18.5517379112056 8.63365743523988 -2.14876928466992 0.0322001852436367 TSSK4 other 0.00102303716520201 1 1 2.57998720088596 -2.14876928466992 2.54957687081253e-11 912.426579030321 374.184428682706 2.43844080375675 0.0151499501540087 -1643.62290620602 517.319810110768 -3.17718918564919 0.00159306535260356 NOVA1 other 1.90376904943572e-07 1 1 2.43844080375675 -3.17718918564919 1.96204829569029e-05 30.8195185580453 54.106486345662 0.569608574490557 0.569238594248885 -204.139049468359 71.9091171577998 -2.83884794497461 0.0047407423139776 MDGA2 other 0.105872126035448 1 1 0.569608574490557 -2.83884794497461 3.07539217915237e-06 337.66860668925 118.460918070345 2.85046420532327 0.00457168707219316 -128.025975563608 155.948510827563 -0.820950292402405 0.412121169498037 TMX1 other 0.0179387625809958 1 1 2.85046420532327 -0.820950292402405 0.00317763244605871 180.269413187667 66.7609285550415 2.70022327564006 0.00719775084043019 47.6699671039658 87.8877823945414 0.542395834838205 0.587821701733552 FRMD6 other 1 1 1 2.70022327564006 0.542395834838205 6.12847711330531e-13 145.7482936843 88.2353507218985 1.65181293542621 0.0992926631575483 -371.704540540787 109.209462389678 -3.403592806038 0.000726520957479622 PELI2 other 4.74160274256432e-09 1 1 1.65181293542621 -3.403592806038 2.10607929746254e-07 -1793.1957022618 1609.50566473067 -1.11412823300741 0.265835167692371 -7428.26350684167 1856.01179579222 -4.00227171167896 7.36638684458727e-05 RTN1 other 0.00133272697943429 0.591815519094141 1 -1.11412823300741 -4.00227171167896 2.64007937090094e-08 -177.762254627031 98.9719633928065 -1.79608697790016 0.0731744670525073 -558.062310712284 116.082243765276 -4.80747349991542 2.10912038351973e-06 C14orf37 other 0.000176225298007638 0.0183936388646755 1 -1.79608697790016 -4.80747349991542 0.0492376922937744 -21.4156433069251 174.23244269643 -0.122914211472304 0.902231539376723 -277.810312960131 198.679089539697 -1.39828662192768 0.162736223819051 SYT16 other 1 1 1 -0.122914211472304 -1.39828662192768 0.00411756119196031 22.0701881054009 20.6429035641631 1.06914165620168 0.285598752851476 -19.4026886804502 23.693424591686 -0.818906047345243 0.413288418217445 SLC38A6 other 1 1 1 1.06914165620168 -0.818906047345243 6.0537341690551e-23 31.178265935867 56.4360996067697 0.552452528667078 0.580922094420674 -422.061844547065 69.3231983534132 -6.08832042623557 2.50883511681967e-09 NAA30 other 5.29822814475702e-19 2.33672902780584e-05 1 0.552452528667078 -6.08832042623557 0.584714531373108 -1.78171893111108 3.70981240981487 -0.480271974506656 0.631274331689943 -3.77218758810803 4.23033816514466 -0.891698828993979 0.37304509030645 RDH12 other 1 1 1 -0.480271974506656 -0.891698828993979 2.70949982968432e-37 -166.977858408314 114.780736506438 -1.45475507032445 0.146454971750567 -1137.99084009623 130.763078485788 -8.70269232931766 6.67498383485783e-17 DCAF5 other 2.51251919206627e-33 6.51411672443775e-13 1 -1.45475507032445 -8.70269232931766 0.00110848173213003 -197.410747244638 191.974558192409 -1.02831723694751 0.304368153857563 -596.136920770528 218.29064009633 -2.73093212108159 0.00657049522555046 RAB15 other 1 1 1 -1.02831723694751 -2.73093212108159 1.59476515878121e-20 22.279013658531 22.969937694058 0.969920508939573 0.332621404416987 -114.763740001943 26.1416804801662 -4.39006742848897 1.4220821187944e-05 WDR89 other 1.36926536532955e-16 0.11938379387279 1 0.969920508939573 -4.39006742848897 0.0527626883167938 -4.6247763122538 11.077310212159 -0.417499936688369 0.676517344472574 -20.2345448204493 12.6068911462852 -1.60503843379434 0.109206080786263 ESR2 other 1 1 1 -0.417499936688369 -1.60503843379434 0.448487613218833 -35.4222710094979 92.5069741966868 -0.382914599867721 0.701968844806539 -100.661446809485 105.280553819802 -0.956125734119682 0.339536128803559 KCNH5 other 1 1 1 -0.382914599867721 -0.956125734119682 6.27954276663333e-06 -186.61028103878 162.846825124485 -1.14592520238653 0.252453215696352 -683.918117440418 188.839539409941 -3.62168918425361 0.000327024465476469 STON2 other 0.0356301256578775 1 1 -1.14592520238653 -3.62168918425361 1.07637407804716e-11 -23.6825889285276 24.1603027420429 -0.980227325020887 0.327517511131453 -135.821284486573 28.0538217374273 -4.84145389379765 1.79273973944634e-06 EFCAB11 other 8.10940230400731e-08 0.0156721308022399 1 -0.980227325020887 -4.84145389379765 0.0414862156404392 23.1992766512507 38.4498536547535 0.60336449806962 0.54657926418146 82.9782235710896 44.587007754022 1.86104041851978 0.0634097901951672 GPR65 other 1 1 1 0.60336449806962 1.86104041851978 2.04359648193553e-17 -71.1915998588231 70.3389446629144 -1.01212209253344 0.312038458735862 -455.55207770599 80.6334593344658 -5.64966555405207 2.89845091015243e-08 PTGR2 other 1.698841755433e-13 0.000265932871006485 1 -1.01212209253344 -5.64966555405207 0.00260259671558156 26.6534800642554 56.9142611529452 0.468309339773905 0.639796350338664 -87.5578132617256 64.2350992308609 -1.36308364601482 0.173556447257103 JDP2 other 1 1 1 0.468309339773905 -1.36308364601482 0.0458805099133608 -8.66222410071812 9.78758034576966 -0.885022017158926 0.376631452573499 8.16396844588719 11.6664876525724 0.699779461394885 0.484437376926199 AK7 other 1 1 1 -0.885022017158926 0.699779461394885 0.15864874054768 -63.0435127090507 68.9183394483228 -0.914756699213897 0.360822676850437 18.7587841610848 80.7992995603869 0.23216518290564 0.81651815387683 FAM181A other 1 1 1 -0.914756699213897 0.23216518290564 0.174303057830724 -286.541492937856 227.694654365466 -1.25844628955556 0.20890231522947 -491.225726850891 269.102208919289 -1.82542435762102 0.0686193926988026 SLC24A4 other 1 1 1 -1.25844628955556 -1.82542435762102 0.502818736690533 198.444137168141 182.099218983543 1.08975831019942 0.276421553425567 244.485066371682 213.486241206416 1.14520291794961 0.252753334886234 FBLN5 other 1 1 1 1.08975831019942 1.14520291794961 0.863335792305622 230.892167935188 562.249277995448 0.410658006993576 0.681524141777259 76.8272526393365 665.574867171446 0.115429918449049 0.908157265750669 WARS essential 1 1 1 0.410658006993576 0.115429918449049 2.37973470933525e-29 -29.015227185415 29.5898686648618 -0.980579789455801 0.3273463004307 -288.060026432513 35.0435178293515 -8.22006591447968 2.37398433580507e-15 WDR20 other 2.14818652211693e-25 2.30751277440253e-11 1 -0.980579789455801 -8.22006591447968 8.51567551038136e-11 101.988686427238 59.1889252890746 1.72310421128838 0.0855869197167744 -463.363197405982 102.033852566159 -4.54126925282506 7.26692793504614e-06 NIPA2 other 6.28031068890626e-07 0.0619505606462683 1 1.72310421128838 -4.54126925282506 0.000404087251858034 -4.95804822323246 115.297760233902 -0.0430021208839979 0.965719484241837 -595.422718732605 184.78810977149 -3.22219172796836 0.00136729730197291 SLC12A6 other 1 1 1 -0.0430021208839979 -3.22219172796836 0.15465962168004 12.8046679586273 10.2533845525423 1.24882353656115 0.212399722400552 -5.26127273136985 15.5029234774948 -0.339372940788072 0.7344922060535 DUOXA1 other 1 1 1 1.24882353656115 -0.339372940788072 1.91874644977745e-16 113.65641448483 47.961825380924 2.36972662283273 0.018236743303814 -366.997402127997 72.5224633031567 -5.06046520502045 6.18271506115847e-07 MFAP1 essential 1.57644208313715e-12 0.00549148751732096 1 2.36972662283273 -5.06046520502045 0.0809009830443737 948.374792789052 1581.91682741401 0.599509896066646 0.549145752401609 -3099.19963738086 2413.04768827179 -1.28435076208564 0.199704402554769 TCF12 other 1 1 1 0.599509896066646 -1.28435076208564 0.000159919130966895 217.52016174577 147.797110294659 1.47174840774698 0.141811896111844 -469.969119208441 223.482121927748 -2.10293832524278 0.0360450733884007 SORD other 0.773368917355906 1 1 1.47174840774698 -2.10293832524278 9.37156237219024e-06 1148.35136783608 663.425275480157 1.73094304705976 0.0841710194648909 -2406.53633632278 1003.15688181736 -2.39896309335286 0.016861560188488 SERF2 other 0.0522745749120772 1 1 1.73094304705976 -2.39896309335286 2.05439741489769e-08 26.2406483088096 52.6418687547704 0.498474862871042 0.618400748749195 -345.043310724024 79.5935097172554 -4.33506842391724 1.81130944770967e-05 ZSCAN29 other 0.000138117138203572 0.151316791261666 1 0.498474862871042 -4.33506842391724 0.84446615037117 4.63119408702713 27.4208636280224 0.168893079001871 0.865959067849508 -13.2646866620096 41.4598270779428 -0.319940713623154 0.749166532147982 DUOX2 other 1 1 1 0.168893079001871 -0.319940713623154 5.70745712170745e-07 4.24017191504348 27.4662252950298 0.154377671831402 0.877383391876868 -175.568116073943 42.3168863327777 -4.148890225365 4.01793197671455e-05 LYSMD2 other 0.00352207178980567 0.328948090933621 1 0.154377671831402 -4.148890225365 0.891138886943593 2.19439687225369 17.2127467409607 0.127486734411291 0.898613948564446 -7.1430583410325 26.0253474543144 -0.274465436189531 0.783856959014163 FGF7 other 1 1 1 0.127486734411291 -0.274465436189531 1.00888213531554e-08 83.0943441636592 60.467599115797 1.37419618735864 0.170083538984511 -372.877817890091 94.978916506181 -3.92590094314064 0.000100329899874999 BNIP2 other 6.8876383377992e-05 0.798325013305367 1 1.37419618735864 -3.92590094314064 3.79562150668869e-17 115.10402269211 42.8341334203638 2.68720325359467 0.007479604407918 -349.797438542204 67.2813149726083 -5.19902797209915 3.08000903807843e-07 GTF2A2 essential 3.14732935334626e-13 0.00276153610354112 1 2.68720325359467 -5.19902797209915 5.21464524409063e-15 397.225487623541 291.579878597148 1.36232132866875 0.173798223757498 -2487.83530132074 445.088875266904 -5.58952478834452 4.01503481944086e-08 SRP14 essential 4.19205331172446e-11 0.000367415836327033 1 1.36232132866875 -5.58952478834452 4.87144980276504e-11 54.0634635896484 54.7879215463521 0.986777049826742 0.324297977674996 -411.896611073402 84.4908113982268 -4.87504622404474 1.52517108539399e-06 BAHD1 other 3.61656433357277e-07 0.0133696497345637 1 0.986777049826742 -4.87504622404474 0.12744295870804 -88.2631629981539 104.109316912476 -0.847793123763899 0.397017288789683 -317.134029865217 160.551457543582 -1.97527966869519 0.0488652559123207 DISP2 other 1 1 1 -0.847793123763899 -1.97527966869519 7.01444844096916e-11 75.2079399238354 30.7318492975907 2.44723118337469 0.0147895074352678 -162.600817991302 46.4659747755508 -3.49935234925618 0.000514366458408768 CDAN1 essential 5.18437884272031e-07 1 1 2.44723118337469 -3.49935234925618 2.15742934213687e-07 760.107153634914 172.214633240272 4.41371989901938 1.2817607333439e-05 -103.789464948541 298.781483163814 -0.347375827476017 0.728476229186838 TLE3 other 0.00136457405890157 1 0.110897938648914 4.41371989901938 -0.347375827476017 4.79634733799791e-14 665.408855659828 155.643089733238 4.27522260577258 2.34635240497445e-05 -864.781769623089 270.03090457368 -3.2025288771609 0.0014618299520775 ANP32A other 3.79630891802535e-10 1 0.200777375293664 4.27522260577258 -3.2025288771609 7.56898511143096e-05 230.74048718357 106.653241792301 2.1634643570696 0.0310493428839867 -352.297753618241 185.054347191787 -1.9037529188824 0.0576020130163443 COMMD4 other 0.380795640956091 1 1 2.1634643570696 -1.9037529188824 0.000242429081168942 31.4411474424197 64.7371389166113 0.485674034543285 0.627442269035939 -345.288592507439 112.320203765703 -3.07414499734794 0.00224363624146813 UBE2Q2 other 1 1 1 0.485674034543285 -3.07414499734794 0.153228084929633 -80.0220684374398 61.3926291152257 -1.30344749183569 0.193111466868009 -215.557814971864 112.519291242523 -1.91574095954135 0.0560533066076783 PSTPIP1 other 1 1 1 -1.30344749183569 -1.91574095954135 1.18527748951618e-11 70.9414857901297 92.0087749058096 0.771029566068599 0.441107995657053 -918.519636164897 164.005710394168 -5.60053448113084 3.79371924143132e-08 ETFA other 8.92513949605683e-08 0.000347504682515109 1 0.771029566068599 -5.60053448113084 0.265144366011797 6.63660935073946 17.8524954499565 0.371746872550282 0.710261506188073 -37.039565242394 32.7168773303622 -1.13212409816447 0.258203088871929 BCL2A1 other 1 1 1 0.371746872550282 -1.13212409816447 0.000913616783784944 97.6045776657285 104.155917206513 0.93710064952148 0.349226760781776 -488.260887938572 190.89506593366 -2.55774493463468 0.0108733282667185 HMG20A other 1 1 1 0.93710064952148 -2.55774493463468 0.0043615515967509 -60.6002289916432 71.8350720623853 -0.843602257947411 0.399355353684824 -414.990894512148 131.658010274243 -3.15203680845338 0.00173347629669168 SCAPER other 1 1 1 -0.843602257947411 -3.15203680845338 6.06066589662221e-12 860.024369189395 899.856827009563 0.955734671756016 0.339737124156245 -9312.13934899922 1649.24118504238 -5.64631749040389 2.96297712934576e-08 TSPAN3 other 4.58913621692234e-08 0.000271793892074886 1 0.955734671756016 -5.64631749040389 4.12468847281418e-10 37.047790448397 50.2260675223157 0.737620766983926 0.461141716608201 -480.877144246874 92.0494011107895 -5.22412029240795 2.71691389526804e-07 WDR61 essential 2.98132482815009e-06 0.00244006036934023 1 0.737620766983926 -5.22412029240795 0.00703031532413111 95.0885209361577 127.471913007409 0.745956647960801 0.456096514582661 -463.267526402375 221.176883613275 -2.09455671331545 0.0367883787919186 NEIL1 other 1 1 1 0.745956647960801 -2.09455671331545 0.0752011871236208 -128.63937019222 125.243242896031 -1.02711625168479 0.30493521075696 -520.701842944385 229.533508603488 -2.26852212608261 0.0237855667138229 DNAJA4 other 1 1 1 -1.02711625168479 -2.26852212608261 0.00105211727026081 -173.945971757964 194.043025780283 -0.896429908050004 0.370515617715578 -1103.10774788119 321.777321427839 -3.42817120543584 0.000665127028543023 TPM1 other 1 1 1 -0.896429908050004 -3.42817120543584 0.00135271011686479 565.333520147239 195.073931299764 2.89804750629908 0.00394383745896402 -107.230284233123 360.064664744798 -0.297808407023566 0.765990927395644 IGF1R other 1 1 1 2.89804750629908 -0.297808407023566 0.305766061684326 -168.823462603219 170.939263446505 -0.987622499356631 0.323882819207128 -515.172231029499 338.426145617592 -1.52225895575935 0.128665815333741 ARRDC4 other 1 1 1 -0.987622499356631 -1.52225895575935 0.0179250732009197 54.376743835307 20.5951270056031 2.64027232366731 0.00858118703536074 23.6760030307278 35.1600279723915 0.673378390066092 0.501063374886968 PIF1 other 1 1 1 2.64027232366731 0.673378390066092 2.6701518509294e-07 121.277936962752 74.2131797067946 1.63418327367057 0.102940524458908 -416.036348751535 124.803870694294 -3.33352119959975 0.000930543445833153 USP3 other 0.0016789914838644 1 1 1.63418327367057 -3.33352119959975 0.497397056725388 -11.7959606578206 10.0578499873725 -1.17281135358255 0.241511823139028 -9.53741931336473 17.4505666906556 -0.546539231787345 0.58497490455191 CYP11A1 other 1 1 1 -1.17281135358255 -0.546539231787345 5.12772116933848e-06 93.6794067054949 41.7469837024714 2.24398024473201 0.0253335933641005 -172.433533512389 72.4283730920671 -2.38074564084437 0.0177053105110786 BBS4 other 0.0293613314156321 1 1 2.24398024473201 -2.38074564084437 0.00234737120476658 -26.0708378553117 94.0471636253659 -0.27721025122208 0.781750051023059 -493.018839171256 163.173670612697 -3.02143622387136 0.0026638773855238 PML other 1 1 1 -0.27721025122208 -3.02143622387136 0.150775974554106 31.9562324172262 17.8000795168932 1.79528593604867 0.0732989739307894 10.7599545552914 33.6102111308782 0.320139451471821 0.749015630961536 ADAMTS17 other 1 1 1 1.79528593604867 0.320139451471821 3.78118060295231e-08 28.6838644232853 12.7200718220797 2.2550080553394 0.0246269680534859 -82.9349734905859 24.0181117805845 -3.45301804938838 0.000608383221326724 LINS1 other 0.000249860414243088 1 1 2.2550080553394 -3.45301804938838 1.26305490993551e-06 141.818181818182 98.1996866292779 1.44418161285557 0.149407742978887 -570.160173160173 170.386559266601 -3.34627435177005 0.000890138546989551 ULK3 other 0.00758969695380249 1 1 1.44418161285557 -3.34627435177005 0.207499322672942 -129.412629329796 294.124444355004 -0.439992771133286 0.660160871194317 -938.195795660277 555.421075647787 -1.68916131705312 0.0919050947637145 PCSK6 other 1 1 1 -0.439992771133286 -1.68916131705312 0.9318542388547 -10.1173723477873 27.5820912403331 -0.366809472843476 0.713939092538296 -13.2535498338053 47.855468441215 -0.276949537127316 0.781950105226232 CCDC33 other 1 1 1 -0.366809472843476 -0.276949537127316 0.298888015293235 -37.8621631408987 32.6926184584041 -1.15812574600202 0.247445262922504 -85.9672269668333 56.7196227621522 -1.51565230479984 0.130330268488039 CELF6 other 1 1 1 -1.15812574600202 -1.51565230479984 2.90094838218324e-07 151.461869129122 130.181313956893 1.16346858489441 0.245277226914059 -860.138315858101 225.877973008795 -3.80797784042718 0.000160239140809029 SCAMP2 other 0.00182092529949642 1 1 1.16346858489441 -3.80797784042718 0.160326792016844 40.0739273370987 22.3407623497642 1.79375827510746 0.0735414051439199 16.0128550956757 42.5185282554848 0.376608875064015 0.70664666460485 HAPLN3 other 1 1 1 1.79375827510746 0.376608875064015 0.498509001100596 2.18066419144089 6.46606856981346 0.337247303813204 0.736092398691523 -9.60816085094254 12.3067016987548 -0.780725907406587 0.435386420908406 RHCG other 1 1 1 0.337247303813204 -0.780725907406587 1.9957863799862e-06 222.213910733433 65.1274129702862 3.41198737365503 0.000704937975262757 -188.348082580288 123.955326978546 -1.51948356856731 0.129363966253411 POLG other 0.0118230385150383 1 1 3.41198737365503 -1.51948356856731 0.0779269168177744 -60.0342843411152 28.8018490828835 -2.0843899351168 0.0377048744854005 -101.872326941054 54.8178172267399 -1.85837984974274 0.0637872775444345 RLBP1 other 1 1 1 -2.0843899351168 -1.85837984974274 0.00107109601137423 362.070987572821 103.720122804826 3.49084611338287 0.000530443187131307 146.601701673687 197.407837194346 0.742633644931531 0.458102511623322 FANCI other 1 1 1 3.49084611338287 0.742633644931531 0.458795335952512 -1013.09657605506 889.919642570666 -1.13841354611365 0.255571550386165 -1761.75103911946 1693.76112528538 -1.04014138287807 0.298849347838619 ABHD2 other 1 1 1 -1.13841354611365 -1.04014138287807 0.502422779576395 -2.83903207451736 6.73878262655994 -0.421297470455231 0.673744542120043 -14.7833336845653 12.8251272283904 -1.15268514856056 0.249668336660707 WDR93 other 1 1 1 -0.421297470455231 -1.15268514856056 1.31091556441379e-12 171.246048638624 23.7704692494352 7.20415095056203 2.56922380511922e-12 75.8501538396686 45.2395201473021 1.67663480056147 0.0943274411942044 TICRR other 1.00717642813911e-08 1 2.46953792148059e-08 7.20415095056203 1.67663480056147 0.0644562340906543 -119.711382782486 209.006815609958 -0.572763057669314 0.567099705416977 -930.438474462764 412.866492209145 -2.25360617056671 0.0247158349221562 NTRK3 other 1 1 1 -0.572763057669314 -2.25360617056671 0.00827548647383562 18.9968293596306 15.2357741632223 1.24685684863242 0.213116338073872 -52.8743477718132 29.5202201485233 -1.79112308464469 0.0739638826965578 DET1 other 1 1 1 1.24685684863242 -1.79112308464469 0.89306172721151 -119.58965475354 287.105998412372 -0.416534852684521 0.677223179488427 -227.097848877431 546.441448963194 -0.415594112248113 0.677911027626466 MFGE8 other 1 1 1 -0.416534852684521 -0.415594112248113 0.00284657248068209 33.175024235016 62.4400074725654 0.531310382203146 0.595473041509426 -309.692947610215 118.834674503531 -2.60608234847325 0.00947053732122029 ZNF710 other 1 1 1 0.531310382203146 -2.60608234847325 1.14018227549617e-07 365.001985462193 95.6697181720024 3.81523006899596 0.000155659501104263 -316.3597718665 185.374145947253 -1.70660137232145 0.088606587729996 UNC45A essential 0.000731084875048145 1 1 3.81523006899596 -1.70660137232145 0.477466846900987 -6.41990440004855 35.1543871882244 -0.182620290482521 0.855180458023689 -77.16096743882 68.6146759771438 -1.12455486147778 0.261393609198757 ST8SIA2 other 1 1 1 -0.182620290482521 -1.12455486147778 0.00103701200180978 -11.1210520168863 85.3964960391072 -0.130228434803618 0.89644562221853 -539.265281663122 165.468267520936 -3.25902536928955 0.00120526887447898 FURIN other 1 1 1 -0.130228434803618 -3.25902536928955 0.119891659442561 219.807542358595 286.450422577804 0.767349338780926 0.443287279941311 -664.255173649157 545.167178965963 -1.21844307448785 0.223711524067855 IQGAP1 other 1 1 1 0.767349338780926 -1.21844307448785 5.65935585639098e-09 244.037006345697 65.9216395772873 3.70192561821198 0.000241329294944365 -310.856924368904 127.732869601559 -2.43364863984165 0.0153473413137488 CRTC3 other 3.90835115442361e-05 1 1 3.70192561821198 -2.43364863984165 9.47749609075468e-11 110.585748788648 26.5349338441352 4.16755321261483 3.71439580577657e-05 -139.770153463046 52.0239062324043 -2.68665241780684 0.00749301460382077 EFL1 other 6.98207137005897e-07 1 0.314832188497622 4.16755321261483 -2.68665241780684 0.23148114994045 -103.767025638081 69.9383268926444 -1.48369328018618 0.138614485616114 -207.519858196726 140.000896581466 -1.48227520868747 0.138991135058207 SH3GL3 other 1 1 1 -1.48369328018618 -1.48227520868747 5.40991600449836e-11 311.544270688771 98.034269328961 3.17791189572048 0.00158894329459741 -689.895494071661 186.099113248939 -3.70714014713659 0.0002366293238754 SEC11A other 4.01037073413464e-07 1 1 3.17791189572048 -3.70714014713659 0.000267908255603524 216.400377072741 143.686408290143 1.5060601740129 0.132772548437586 -1083.81977777434 339.84433780177 -3.18916532429186 0.0015292499541732 FTO other 1 1 1 1.5060601740129 -3.18916532429186 0.293551083686209 -156.528906157002 583.709297527771 -0.268162434314412 0.788700534953491 -2235.00414038186 1432.9931477026 -1.55967538572328 0.119558832920648 NKD1 other 1 1 1 -0.268162434314412 -1.55967538572328 8.62780478419463e-10 475.134702804704 87.4280555525186 5.43457932127161 9.14558571689748e-08 -366.823312462468 208.660605388648 -1.75799026260481 0.079449211054906 DHX38 other 6.15593871352287e-06 1 0.000837278372381964 5.43457932127161 -1.75799026260481 0.000139146290524345 114.677030620122 28.4984332836957 4.02397666842023 6.74353905084675e-05 1.67876552643703 68.0159281139661 0.0246819469054972 0.98031992138815 TXNL4B other 0.677364142272509 1 0.5654457494135 4.02397666842023 0.0246819469054972 0.131162479635542 -64.5240157818027 47.3696282813791 -1.36213895111284 0.173855720358202 -210.247471715179 113.054959895457 -1.85969259473089 0.0636007902698071 MARVELD3 other 1 1 1 -1.36213895111284 -1.85969259473089 0.532630859191624 -17.4071469686839 52.4897579735571 -0.331629400490913 0.740327735852979 -140.606551128673 125.273414766186 -1.12239736891586 0.262308412801593 ZFHX3 other 1 1 1 -0.331629400490913 -1.12239736891586 0.495829390076202 -2.3920720608595 25.8821604437987 -0.0924216533644367 0.926405292677319 66.9671276777795 61.7710339215964 1.08411861395712 0.278908598385648 CLEC18B other 1 1 1 -0.0924216533644367 1.08411861395712 0.0119114073359191 516.008159678638 202.864304377589 2.54361239776416 0.0113139622977207 -319.107644991216 467.521412619554 -0.682551935328981 0.495250834564354 CPNE2 other 1 1 1 2.54361239776416 -0.682551935328981 0.89266371488396 -31.4431751611015 96.1857696103585 -0.326900489422452 0.743899312931453 -95.9611892208563 221.669884310616 -0.432901336684915 0.665299534385403 NLRC5 other 1 1 1 -0.326900489422452 -0.432901336684915 0.000162480889613756 187.291746155551 56.6980947909199 3.30331639618948 0.00103386182005775 -170.768461622238 131.813222901026 -1.29553361843267 0.195818563855181 KATNB1 essential 0.784457735055213 1 1 3.30331639618948 -1.29553361843267 0.496098308608698 -9.09952886368469 104.888835779533 -0.0867540267375173 0.930906676524105 -277.21365908843 243.848325793319 -1.13682822380085 0.256231666432702 KIFC3 other 1 1 1 -0.0867540267375173 -1.13682822380085 0.704668377169951 2.09759134429614 10.5918100670484 0.198038987766769 0.843106649860608 -16.8884905471356 24.4459988250766 -0.690848865206172 0.490027313169255 ADAMTS18 other 1 1 1 0.198038987766769 -0.690848865206172 0.0558854470450485 31.4861963848702 17.5346341534887 1.79565744624365 0.0732397340563415 -35.1705236643624 40.4701031458151 -0.869049518792721 0.385297089665455 NUDT7 other 1 1 1 1.79565744624365 -0.869049518792721 0.000893582199015916 75.2431870991229 35.3413633247484 2.12904030916183 0.0338081913061525 -176.748707021168 81.5668316232774 -2.1669188750336 0.0307794272514833 GCSH other 1 1 1 2.12904030916183 -2.1669188750336 0.000883015318803699 420.277109723842 111.453893206998 3.77086073559836 0.00018500819648515 277.535359267861 257.232321725627 1.07892879637377 0.281213264713532 CMTM3 other 1 1 1 3.77086073559836 1.07892879637377 0.000513035154813263 739.863281542793 203.600825744565 3.63389135990546 0.000312288356562322 -50.3771964578271 469.904743607833 -0.107207252412566 0.914673649636291 CDH11 other 1 1 1 3.63389135990546 -0.107207252412566 0.996098674406184 3.46210982783182 40.0661532119861 0.0864098384867181 0.931180203481452 4.44457086428307 92.4730643908242 0.0480634106111021 0.96168766439278 NOL3 other 1 1 1 0.0864098384867181 0.0480634106111021 0.00163800817761266 74.7192888858275 221.263521816729 0.337693661713099 0.735755833506001 -1477.65428699275 470.145518145188 -3.14297218619114 0.00178601940401523 MAP1LC3B other 1 1 1 0.337693661713099 -3.14297218619114 3.89006705044438e-09 545.680369208363 100.831808770345 5.411787965157 1.02951484301647e-07 -283.935409951919 232.716861901075 -1.22008954414578 0.223087439529037 MBTPS1 essential 2.7032075933538e-05 1 0.000941697226907165 5.411787965157 -1.22008954414578 0.123206076291563 56.8897086380615 140.911341315126 0.403726968369684 0.686610537462023 -565.530476465815 325.219249332477 -1.73892067467281 0.082751327079198 CDH13 other 1 1 1 0.403726968369684 -1.73892067467281 1.93369960433964e-05 295.56205899563 109.950858749343 2.68812870001706 0.00745924749054771 -571.211062540876 233.625963433931 -2.44498108919479 0.0148789979363861 ZCCHC14 other 0.104381104642254 1 1 2.68812870001706 -2.44498108919479 8.89871912126094e-05 29.7903821790543 12.3383357030432 2.41445709502836 0.0161676434312488 -68.3794869087839 27.6289972629263 -2.47491743033825 0.0137042298448955 TLDC1 other 0.443423173812433 1 1 2.41445709502836 -2.47491743033825 0.000879148306643385 -7.27501097559665 24.5262097178075 -0.296621902010181 0.766895790250161 193.720431028634 56.6057738075059 3.42227334772247 0.000679336303744903 ADAD2 other 1 1 1 -0.296621902010181 3.42227334772247 0.148029189468996 -11.1813596890425 13.2274499228636 -0.845314838026002 0.398396602345583 -59.5866679516138 30.5285670716618 -1.95183310804408 0.0515949145837974 OSGIN1 other 1 1 1 -0.845314838026002 -1.95183310804408 0.26253460158853 -101.89386035751 76.5199662447424 -1.33159834430155 0.183684776623302 58.6978351765865 165.511250481653 0.354645590591398 0.723025804908833 IRF8 other 1 1 1 -1.33159834430155 0.354645590591398 1.06645991682061e-07 152.387324989786 63.4267071381138 2.40257348782048 0.0166972776711676 -492.147992721063 130.738155093363 -3.76437920796426 0.000189826378560731 DEF8 other 0.000685693251827089 1 1 2.40257348782048 -3.76437920796426 1.60625473451671e-05 462.744475804952 161.664024895308 2.86238373753605 0.00440722749414902 -752.380937349128 333.22960174736 -2.25784544171304 0.0244490862268851 TCF25 other 0.0874766328417801 1 1 2.86238373753605 -2.25784544171304 0.0585053253268282 56.037867678773 28.735310685064 1.95013961369488 0.0517985043589172 -28.5648581040275 61.0592373503703 -0.467822058440012 0.640145060704671 GALNS other 1 1 1 1.95013961369488 -0.467822058440012 0.416630969764576 -10.1702937571952 32.3843013287384 -0.314050121197764 0.75363317927548 -86.801237295899 66.7520670825214 -1.3003527993911 0.194167013814064 GAS8 other 1 1 1 -0.314050121197764 -1.3003527993911 1.09985226686436e-06 174.432673915754 36.5569767724704 4.77152897520542 2.49506677571892e-06 -71.6419965487132 27.1328303862184 -2.64041736630258 0.00857620668731923 MED9 other 0.00664310769186071 1 0.0221287472338511 4.77152897520542 -2.64041736630258 0.0180230535280564 122.058945992254 146.429854105304 0.833565987878921 0.404980972297715 -300.963220906652 108.739627084887 -2.76774188927195 0.00588443129392801 NCOR1 other 1 1 1 0.833565987878921 -2.76774188927195 1.48728151562251e-05 200.932219115139 45.0008577566772 4.46507531482163 1.01961933276915e-05 -65.4916394652589 33.3999348016586 -1.96083135653327 0.0505319927651655 COPS3 essential 0.0813394260893949 1 0.0885437428576729 4.46507531482163 -1.96083135653327 0.00957431392437541 18.6843441168722 16.3163651644123 1.14512907308699 0.252781018700892 -35.210831704714 12.1101143368887 -2.90755567826954 0.00382770909327208 GID4 other 1 1 1 1.14512907308699 -2.90755567826954 0.00853671840332202 22.9509470110199 12.5854604757118 1.82360804797822 0.0688942583197781 -24.4541450040812 9.34603320601758 -2.61652665521625 0.00919074790688075 ZNF287 other 1 1 1 1.82360804797822 -2.61652665521625 0.0540039004314186 90.2775322991214 95.98495100104 0.940538400630566 0.347462251736035 -388.333989721916 203.261300311742 -1.91051611460877 0.0567224525095189 KSR1 other 1 1 1 0.940538400630566 -1.91051611460877 3.20163354043471e-05 177.280409731112 49.304335567992 3.59563530648614 0.000360597475572204 -161.538869581122 113.796801318447 -1.41953787548979 0.156456818458862 UTP4 other 0.168886169257931 1 1 3.59563530648614 -1.41953787548979 0.000386048410385294 68.6991080319956 30.4794576661612 2.25394784856249 0.0246930173030063 -161.508710876011 70.3456957384446 -2.29592882948409 0.0221514542422088 RANBP10 other 1 1 1 2.25394784856249 -2.29592882948409 3.39092467776468e-05 43.1832442793049 10.2316539230424 4.22055364695761 2.96437623804492e-05 -4.69384688417985 23.6143576324354 -0.198770890033978 0.842534199645132 CTRL other 0.1783965472972 1 0.252505567956666 4.22055364695761 -0.198770890033978 1.63622318014747e-05 120.150328197111 38.7755523232531 3.0986103613812 0.00206950158437578 -203.95727905142 89.492839265642 -2.27903462137359 0.0231454110467776 GFOD2 other 0.0890596276954268 1 1 3.0986103613812 -2.27903462137359 6.47652393158661e-05 159.291786526984 49.1095431708988 3.2436014721753 0.0012708210440546 -191.742600861564 113.345294813277 -1.6916679353778 0.0914222080431891 NOB1 essential 0.328424528570757 1 1 3.2436014721753 -1.6916679353778 1.52971812093694e-05 197.34086135927 50.7922670672604 3.88525405054172 0.000118022593981598 -111.868596104828 38.330654767079 -2.91851513585176 0.00369820302732865 PRPSAP2 other 0.0835073122219475 1 0.977109055573651 3.88525405054172 -2.91851513585176 0.700192725058091 44.818547180854 73.7803646751505 0.60745900861546 0.54386403425751 -32.448644078819 52.4753413022448 -0.618359848141301 0.536662536730864 VPS53 other 1 1 1 0.60745900861546 -0.618359848141301 0.0720924151498032 -2.82702168534819 5.67861130889278 -0.497836800508082 0.618848926248336 -9.15122386079359 4.13836504428815 -2.21131383115278 0.0275298396579472 SPATA22 other 1 1 1 -0.497836800508082 -2.21131383115278 0.00333897156803131 -36.9692570039595 186.366610406292 -0.198368457329153 0.842848832580685 486.203977945548 143.058308813818 3.39864200812211 0.00073915782257322 SGSM2 other 1 1 1 -0.198368457329153 3.39864200812211 0.000825472253872097 181.235320127337 122.68114762922 1.47728745312267 0.140318891741828 -874.241727497835 277.03634621997 -3.15569324901389 0.00171186013607335 NPEPPS other 1 1 1 1.47728745312267 -3.15569324901389 0.676884604242242 -3.44543685886065 19.8707886508683 -0.173392054004363 0.862423555904407 36.7040550535424 44.871855136075 0.81797498548336 0.413817244100804 LRRC46 other 1 1 1 -0.173392054004363 0.81797498548336 0.0995797015508438 64.1132826317652 60.0173837554366 1.06824520863853 0.285999656720592 -221.329034955142 135.530169277025 -1.63306100874665 0.103176421137756 SCRN2 other 1 1 1 1.06824520863853 -1.63306100874665 0.913013080981539 26.7448221716839 76.9044926108643 0.347766707297743 0.728183222765067 -21.6177750911345 158.251071406811 -0.136604288988113 0.891406639614282 SSH2 other 1 1 1 0.347766707297743 -0.136604288988113 0.0116136663850182 -494.356030799331 293.610093128252 -1.6837160655216 0.0929506809908779 -1729.75186980152 604.16596528415 -2.86304090133245 0.00439779954161029 RHBDL3 other 1 1 1 -1.6837160655216 -2.86304090133245 0.483707162161511 133.288490082315 117.535228767332 1.13403012424613 0.257403614214858 -49.4362569153948 275.766896702539 -0.179268278776478 0.857810140300497 G6PC3 other 1 1 1 1.13403012424613 -0.179268278776478 1.67204271100865e-20 722.51086931076 98.3840516401486 7.34378039190163 1.04590989528373e-12 -170.279249753021 164.656754963097 -1.03414676058194 0.301647460291603 SS18 other 1.43494705458762e-16 1 1.00689745618964e-08 7.34378039190163 -1.03414676058194 3.48439178191261e-05 23.6287362226788 9.03365358189721 2.61563452798645 0.00921800752804713 -21.3504810386697 15.1177736984179 -1.41227679846167 0.158588421529217 TAF4B other 0.182895724632593 1 1 2.61563452798645 -1.41227679846167 4.39122227832014e-21 350.205794881394 70.0386920291214 5.00017611316587 8.32187206401457e-07 -383.848895359262 109.871178834678 -3.49362680395772 0.000525329321195581 AFG3L2 essential 3.79445517069643e-17 1 0.0074830273599619 5.00017611316587 -3.49362680395772 1.05431238753764e-08 32.5254273954026 20.0069982717842 1.62570251436834 0.104737170569362 -108.69968310765 31.3854017169581 -3.46338352103735 0.000586273879464287 PRELID3A other 7.18830185823161e-05 1 1 1.62570251436834 -3.46338352103735 0.879407464880303 -0.324717213530094 11.2145149508037 -0.0289550832073057 0.976913693178788 -7.07785690341997 17.5924470033164 -0.402323616611476 0.687643496016765 IMPA2 other 1 1 1 -0.0289550832073057 -0.402323616611476 0.00143543063619414 -214.880228310504 150.087196826212 -1.43170258925761 0.15294539891139 -824.942511415525 237.128505940108 -3.47888377293568 0.000554138163872143 GNAL other 1 1 1 -1.43170258925761 -3.47888377293568 0.000705036276605691 599.150888914063 234.191982230037 2.55837489912674 0.0108523907669107 -372.126893896491 420.346253702493 -0.885286571769639 0.376488945688204 SLC39A6 other 1 1 1 2.55837489912674 -0.885286571769639 3.98071096577489e-08 209.630553353719 133.412699516429 1.57129384319147 0.116838134473982 -912.063450722831 239.459642913748 -3.80883993488352 0.000159603517473722 RPRD1A other 0.000262527888192854 1 1 1.57129384319147 -3.80883993488352 2.00039141433249e-19 91.4833069112587 14.2095924879877 6.43813726456937 3.18949362819284e-10 -59.2947420073236 25.5044981134228 -2.32487390042454 0.0205359661276961 C18orf21 other 1.69933250647545e-15 1 3.02236416207554e-06 6.43813726456937 -2.32487390042454 3.19070730150699e-13 480.06435800127 92.873745607278 5.16899964421861 3.58808393080211e-07 -543.073339658441 201.338256450319 -2.69731818102063 0.00726041960140736 GALNT1 other 2.48495792623681e-09 1 0.00325223927487903 5.16899964421861 -2.69731818102063 3.22060806130321e-13 206.272053176111 33.3774033438253 6.17999102720107 1.47050279224625e-09 -92.0367138790993 72.3578891983249 -1.27196515678943 0.204061956430396 ASXL3 other 2.50756543653068e-09 1 1.38374312750372e-05 6.17999102720107 -1.27196515678943 0.649157004299289 -2.65594803085674 20.4446876479565 -0.129908956135224 0.896698645826156 27.9597998768877 39.6600607862568 0.704986309213536 0.48119692017758 ADCYAP1 other 1 1 1 -0.129908956135224 0.704986309213536 3.75730713504218e-07 65.9592690745496 39.3191463382537 1.67753563383897 0.0941528158876928 -370.167936178352 92.9146684005844 -3.98395584411325 7.93931348169392e-05 GAREM1 other 0.00234042661441778 0.636574154962218 1 1.67753563383897 -3.98395584411325 9.17363770099198e-10 88.2651706812271 28.839748472949 3.06053885192576 0.00234977472658423 -129.904347707682 47.319171901798 -2.74527939705442 0.00630300041533203 ESCO1 other 6.54080368080728e-06 1 1 3.06053885192576 -2.74527939705442 0.0421785867226583 227.155101295508 219.964107652511 1.03269166828962 0.302327328286419 -444.799141317433 368.134627214678 -1.20825129839809 0.227613127929427 OSBPL1A other 1 1 1 1.03269166828962 -1.20825129839809 0.681613501638753 2.7169156193407 42.9886192403013 0.0632008114555498 0.949636381869104 -45.8852139812908 70.5341055786522 -0.650539389489025 0.515696215610816 GREB1L other 1 1 1 0.0632008114555498 -0.650539389489025 1.25185795e-13 75.7879502363239 20.7633435299826 3.65008410745046 0.000294797519136869 -114.541269625686 34.0653550445557 -3.36239764640268 0.000842645366215053 C18orf8 other 9.84210720290002e-10 1 1 3.65008410745046 -3.36239764640268 1.57985343981112e-05 566.479923085431 133.479160809856 4.24395778073849 2.68232656421318e-05 -234.890454611419 97.2747496155232 -2.41471148000709 0.0161565094982759 PELP1 essential 0.0861020124697058 1 0.228909748989953 4.24395778073849 -2.41471148000709 0.000127533581494942 -86.8408105612012 156.151059833173 -0.556133340714942 0.578412373356404 -945.393605693489 256.189051927956 -3.69021860449895 0.000253188184152491 NPC1 other 0.623384146347276 1 1 -0.556133340714942 -3.69021860449895 0.223524945182137 -1021.9649069845 937.283034573007 -1.09034823984632 0.276161996050688 -2592.74766401519 1495.39988408709 -1.73381561119887 0.0836576932663945 SLC14A1 other 1 1 1 -1.09034823984632 -1.73381561119887 4.40114839974736e-14 32.1293087363319 106.774444539257 0.300908226448504 0.76362726416506 629.306071448317 77.8133252777078 8.08738181027976 6.03227776534053e-15 ARRB2 other 3.4874699919598e-10 5.85311911570991e-11 1 0.300908226448504 8.08738181027976 0.0707646846166771 -30.4305026958455 38.644296346412 -0.787451333647349 0.431443610135231 -61.8344433872501 28.8866648934101 -2.14058783232384 0.0328588523205921 SLC13A5 other 1 1 1 -0.787451333647349 -2.14058783232384 7.76350375619518e-05 -29.9478356115159 18.287617453475 -1.63760181924765 0.102222964947592 55.6252591461308 13.3273493634364 4.17376761344148 3.61522766050315e-05 ZMYND15 other 0.390038428711246 0.297244018246569 1 -1.63760181924765 4.17376761344148 6.54603072457138e-08 150.086587598779 25.7091744294087 5.83786103326194 1.03068012614809e-08 -13.273996043838 19.3753644266702 -0.685096587167485 0.493645367125259 WRAP53 other 0.000426342981091334 1 9.59047857380797e-05 5.83786103326194 -0.685096587167485 0.0500747708579913 -94.8846609677542 221.295373057089 -0.428769294436518 0.668301920501404 -384.993254426216 161.272005866647 -2.38722927985754 0.0173991758068262 MINK1 other 1 1 1 -0.428769294436518 -2.38722927985754 0.0222608197460796 299.825833191984 120.861089340824 2.48074740040184 0.0134852582589481 -118.219595060769 91.0852916499765 -1.2978999454167 0.195004784786644 SAT2 other 1 1 1 2.48074740040184 -1.2978999454167 0.408463813840733 19.82433396765 22.2745128913296 0.890000785398396 0.373954036552038 -17.186013320647 16.6502291512296 -1.03217878652306 0.302557962101441 ASGR1 other 1 1 1 0.890000785398396 -1.03217878652306 1.11349519022392e-06 -14.0036416564727 40.7674653802794 -0.343500424317445 0.731386843204989 162.022903357347 30.4737366786903 5.31680460016072 1.68666634252505e-07 PIK3R5 other 0.00671994347300138 0.00152069837442058 1 -0.343500424317445 5.31680460016072 0.109809359323128 137.347246323866 131.268049657289 1.04631132009997 0.295994381835397 -183.581090842667 98.9283536377915 -1.85569742234685 0.0641682125892405 TP53 ts 1 1 1 1.04631132009997 -1.85569742234685 0.0599633156051515 112.796164740035 47.501555592796 2.37457833395969 0.0179989536628095 66.5495947783016 133.49468437357 0.4985186870218 0.618368745554665 CCDC40 other 1 1 1 2.37457833395969 0.4985186870218 3.42465552412901e-09 1902.16380581416 297.879556446987 6.38568093931173 4.37733373141359e-10 951.167866163676 785.540219593266 1.21084553335304 0.226610549431418 ARHGDIA other 2.38424517589862e-05 1 4.14183317666354e-06 6.38568093931173 1.21084553335304 0.439773726061537 -131.90488567562 103.344536089462 -1.27636051858063 0.202504451603488 -15.5824053076214 290.431461766442 -0.0536526077885887 0.957236404084225 TMC6 other 1 1 1 -1.27636051858063 -0.0536526077885887 2.49159154794672e-05 27.6425303264175 6.02601086375395 4.58720220580509 5.87274454285372e-06 -2.69663455784648 16.935033142589 -0.159234088008063 0.873557846102885 CARD14 other 0.133001156829396 1 0.05142762396177 4.58720220580509 -0.159234088008063 0.28963961145883 -16.5336057805001 77.565339112238 -0.213157139125967 0.831304719316965 -320.149251449712 203.50590544616 -1.57316934242191 0.116409979617543 RAB40B other 1 1 1 -0.213157139125967 -1.57316934242191 9.77058557672238e-13 454.276867226602 60.5449994380035 7.50312778005341 3.50604071763455e-13 -91.7515519945006 170.150966415929 -0.539236149680258 0.589997909992273 EIF4A3 essential 7.52530501119158e-09 1 3.38017385587147e-09 7.50312778005341 -0.539236149680258 3.21467919004674e-14 945.318732778218 123.391117481834 7.66115707573029 1.20854253300581e-13 -411.633247004854 325.388476904456 -1.26505170349263 0.206530050048664 CSNK1D other 2.55470555233014e-10 1 1.16745208688361e-09 7.66115707573029 -1.26505170349263 4.81889573743569e-10 694.709592387971 103.675175298788 6.7008287218791 6.42089343101429e-11 248.214222237799 273.402515237981 0.90787102679631 0.364447884039544 ANAPC11 essential 3.4773151641336e-06 1 6.11911143975662e-07 6.7008287218791 0.90787102679631 8.67792216490485e-18 940.389094503572 103.759959355455 9.06312126898628 4.44605419173069e-18 -43.6629145179312 272.226523235431 -0.160391845728309 0.872647383962027 TBCD essential 7.24346163104608e-14 1 4.33401362609908e-14 9.06312126898628 -0.160391845728309 1.04353879572139e-13 268.758405266856 43.1345643089091 6.23069711199902 1.10161714175313e-09 -417.140456365991 113.170891356616 -3.68593417764579 0.00025678463928401 FN3KRP other 8.21473739991882e-10 1 1.0383843178165e-05 6.23069711199902 -3.68593417764579 5.20732245516863e-19 570.449926933096 61.042499989086 9.34512719883834 4.87144529472369e-19 -72.9564597496653 160.158601751848 -0.455526327975222 0.648958447044494 NARF other 4.40903992279128e-15 1 4.75940205294505e-15 9.34512719883834 -0.455526327975222 5.45317414732332e-13 394.639850535471 52.418004519772 7.52870801074875 2.94847351205062e-13 -80.7819808498567 141.693310271893 -0.570118523555172 0.568889629096606 RPTOR essential 4.22457401193137e-09 1 2.84409754972403e-09 7.52870801074875 -0.570118523555172 7.94613343615503e-16 489.119944087933 58.0430116568874 8.42685329595393 5.2707353029421e-16 -57.6724213736574 152.288775690631 -0.378704347133347 0.705092612438603 FOXK2 other 6.46974184371742e-12 1 5.11841105268708e-12 8.42685329595393 -0.378704347133347 2.30569033465171e-08 124.208208155988 20.6258827206473 6.02195842176736 3.65128841033794e-09 15.6528595671293 57.9653796461492 0.270038075532024 0.787258145357869 CBX8 other 0.000154504309325011 1 3.42198749816872e-05 6.02195842176736 0.270038075532024 0.414994403009655 2.01114239681982 23.235031047232 0.0865564755532967 0.931063890632262 80.6044373842469 61.2719255452051 1.31551990029722 0.189028167156397 SECTM1 other 1 1 1 0.0865564755532967 1.31551990029722 2.32775814194958e-18 357.693867580165 38.3159100710976 9.33538749089976 5.25921504527316e-19 17.5369573763129 103.563525521592 0.169335268261572 0.865611833583437 CEP131 other 1.95834292482218e-14 1 5.13720125622282e-15 9.33538749089976 0.169335268261572 4.16407054880583e-12 635.810419975856 107.486391281327 5.91526436413457 6.72470061362224e-09 -925.579653091044 282.014500357083 -3.28202859044159 0.00111389196185091 WDR45B other 3.16635924531195e-08 1 6.27481814257092e-05 5.91526436413457 -3.28202859044159 0.0722824797906689 112.450853251747 50.5125504629355 2.22619630608951 0.0265090644936428 -35.4985316275457 141.956550618234 -0.250066174987673 0.802653418530783 CBX4 other 1 1 1 2.22619630608951 -0.250066174987673 0.0251225373834748 74.3783778381873 106.012469522705 0.701600275637931 0.483301944578 -260.769919251674 167.658585190047 -1.55536275673615 0.120583586598478 RNF165 other 1 1 1 0.701600275637931 -1.55536275673615 8.09083230758371e-19 170.285309349519 48.765875984868 3.49189481190408 0.000528306879288606 -334.73560323015 75.8799090061701 -4.41138646071559 1.29439042850422e-05 DYM other 6.83918054960051e-15 0.10897473017577 1 3.49189481190408 -4.41138646071559 0.302527098487296 458.440098388854 604.851831662845 0.757937852529141 0.448895783824707 -472.27213612285 934.104848363276 -0.505587929396104 0.613400287898004 MAPK4 other 1 1 1 0.757937852529141 -0.505587929396104 1.32320012268837e-18 27.6353641099812 11.8074961588833 2.34049316960309 0.0197062462729431 -97.3667888310026 18.2349442155475 -5.33957152158358 1.49941708645933e-07 ELAC1 other 1.1158546634631e-14 0.00135442345419871 1 2.34049316960309 -5.33957152158358 1.18081356569182e-23 124.6408642442 61.018205746704 2.04268320772334 0.0416819789823043 -628.114264740525 94.2336599522699 -6.66549792355163 7.95317308624073e-11 MBD1 other 1.03769896152997e-19 7.53006427805273e-07 1 2.04268320772334 -6.66549792355163 1.14092346235284e-21 288.298804104287 100.571830810204 2.86659596212735 0.00434915709856091 -863.081998016886 155.318426514991 -5.55685514837214 4.77776399889462e-08 SMAD4 ts 9.89865195937321e-18 0.000436639851858979 1 2.86659596212735 -5.55685514837214 0.231846539306548 -4.54640331445637 15.846727427659 -0.286898562192786 0.774325660377926 -37.1465163915435 25.2103481162272 -1.47346304859763 0.141344504991826 TNFRSF11A other 1 1 1 -0.286898562192786 -1.47346304859763 1.31375015933739e-08 -17.9291599855419 22.6643182544592 -0.791074312681537 0.429328774573859 -186.231374257354 36.0563627802794 -5.16500722472238 3.65762855897461e-07 ZCCHC2 other 8.92824608285692e-05 0.00327357756028228 1 -0.791074312681537 -5.16500722472238 0.035633845748777 1.12346566121169 11.9585271530068 0.0939468252935489 0.925194653126839 -32.446840515625 17.8242537401494 -1.82037581986044 0.0693887873901515 FBXO15 other 1 1 1 0.0939468252935489 -1.82037581986044 0.517521573791255 -35.4387165021159 66.2093757215855 -0.535252237555264 0.592748339700639 -109.177291960508 98.5907598757503 -1.10737854235123 0.268740850973638 CBLN2 other 1 1 1 -0.535252237555264 -1.10737854235123 0.220990448530357 -15.8754870636241 11.3754563473895 -1.39559122542519 0.163544710620662 -31.0102159013314 18.3162648280464 -1.69304256039406 0.0911584234814018 PMAIP1 other 1 1 1 -1.39559122542519 -1.69304256039406 0.00146221258044903 201.243391346282 58.0897497055484 3.46435287406757 0.000583850358607623 -24.8764046585712 128.252306110977 -0.193964579763934 0.846293539332262 P3H4 other 1 1 1 3.46435287406757 -0.193964579763934 6.92161082714451e-07 298.432773661832 60.3098466135748 4.94832586084972 1.06942258318805e-06 -113.885903000015 133.153903203193 -0.855295265556168 0.392855315868538 NT5C3B other 0.00424087095379144 1 0.00957988750019856 4.94832586084972 -0.855295265556168 6.7869436512947e-08 310.668453737209 58.2626201544145 5.33220876290559 1.55926939934441e-07 -123.541828619935 127.611273524074 -0.968110615999995 0.333524610523202 RETREG3 other 0.000441558553953233 1 0.0014220536922021 5.33220876290559 -0.968110615999995 0.775517304587094 -42.4061979939685 130.786456550622 -0.324239979523835 0.745911493162585 171.493410695815 306.857574804932 0.558869732333747 0.576536892718019 ERBB2 og 1 1 1 -0.324239979523835 0.558869732333747 0.0099697836108515 136.254486574013 45.7664543317536 2.9771693823237 0.00307094824551178 -7.61710970179524 107.379491378963 -0.0709363548288099 0.943480860391678 MIEN1 other 1 1 1 2.9771693823237 -0.0709363548288099 0.00647294013975734 111.139162506186 35.031189887963 3.17257743347091 0.00161749686530059 80.7271938110019 82.1918893978957 0.982179560567064 0.326554843419545 PNMT other 1 1 1 3.17257743347091 0.982179560567064 0.329252785518432 -140.273602302887 95.278434315462 -1.47224923783328 0.141673393634385 -118.598713623893 223.546918055214 -0.530531642554787 0.596012863653544 STAC2 other 1 1 1 -1.47224923783328 -0.530531642554787 0.196907000824805 328.768485091594 198.923146104373 1.65274122961585 0.0991001191719638 -121.625083567322 435.691771996009 -0.279153960172644 0.780258434717028 IGFBP4 other 1 1 1 1.65274122961585 -0.279153960172644 0.111361217201602 645.37181622902 308.925998439577 2.08908223810515 0.0372769289277725 508.898404278638 682.056161686777 0.74612390132228 0.455992828786718 FKBP10 other 1 1 1 2.08908223810515 0.74612390132228 6.06278815593209e-13 308.836516344954 82.5265483611166 3.74226866963535 0.000207988203812491 -301.374756184651 124.069174164777 -2.42908650124802 0.0155595556115317 TXNL4A essential 4.69138547506025e-09 1 1 3.74226866963535 -2.42908650124802 1.80557588090959e-05 901.117194377197 205.933405960926 4.37576987654047 1.51437914678119e-05 -156.414578290053 572.568734324654 -0.273180439156434 0.784843274386062 NFIC other 0.0977899897100636 1 0.13060005761841 4.37576987654047 -0.273180439156434 0.0732830333753081 37.780563453089 19.0808511069428 1.98002506499 0.0483348407509662 -38.6925212473197 54.9862013796658 -0.703676927601484 0.482013082760633 TPGS1 other 1 1 1 1.98002506499 -0.703676927601484 0.332986898786032 -25.6298785215821 51.3661980488631 -0.498963900291027 0.618058794982532 186.281240022501 148.02443005254 1.25844929756786 0.208909001015048 PLPP2 other 1 1 1 -0.498963900291027 1.25844929756786 0.00585214942214464 53.9293516560959 17.0415180881519 3.16458612296931 0.00166129127095346 31.5331722541025 33.1904811815358 0.950066739967744 0.342602269785042 PRDM15 other 1 1 1 3.16458612296931 0.950066739967744 0.00146284820916179 621.062478445805 260.719191657555 2.38211262660536 0.0176396038125232 -669.686934458801 512.330933428154 -1.30713741990501 0.191851839283296 PFKL other 1 1 1 2.38211262660536 -1.30713741990501 3.42077850621649e-09 786.757621061471 148.519656064812 5.29732994209291 1.86467719277287e-07 -760.036003563493 409.702845747649 -1.85509085780582 0.0642549616678133 SH3GL1 other 2.38214237454911e-05 1 0.00169909385805464 5.29732994209291 -1.85509085780582 2.03987814309348e-70 281.567093964992 39.3449759935899 7.15636715627594 3.54502777160579e-12 -305.782728481173 53.558215416877 -5.7093524513667 2.10275849343945e-08 CCDC97 other 1.99214499454509e-66 0.00019326453313202 3.4046446718502e-08 7.15636715627594 -5.7093524513667 1.44466355530965e-25 65.6301496521488 18.9893894388546 3.45614849089678 0.000601929673393008 -81.7651692231087 25.5121343403392 -3.20495212718536 0.00145056017223985 TMEM91 other 1.28228337169285e-21 1 1 3.45614849089678 -3.20495212718536 1.8775431080005e-31 55.2942755137065 21.9357739584855 2.52073510687855 0.0120667982601405 -137.877967173594 29.2250153685921 -4.71780648990764 3.21558633860453e-06 ZFP14 other 1.70800096534805e-27 0.0278116062425906 1 2.52073510687855 -4.71780648990764 9.58058267163213e-37 147.831733478934 42.2870723415769 3.4959084489182 0.000520751547277184 -266.743043635596 49.0901847532802 -5.4337347674735 9.18624071897441e-08 SIRT3 other 8.87353567046568e-33 0.000834478106911636 1 3.4959084489182 -5.4337347674735 0.603866638149656 481.375854234194 602.127073821578 0.799458910191498 0.424458687359447 193.180209787758 698.99682484737 0.276367792986671 0.782396248564867 IFITM3 other 1 1 1 0.799458910191498 0.276367792986671 0.213261053531792 -12.8111261800738 87.0804627964241 -0.147118260154675 0.883106525385031 -118.041305064878 101.089902193929 -1.16768641083884 0.243569978349826 PGGHG other 1 1 1 -0.147118260154675 -1.16768641083884 0.264480226194688 75.1326753464921 62.9219958546967 1.19406058765194 0.233107994712733 -54.9100004666586 124.544283969189 -0.44088735923234 0.659514587457079 HUNK other 1 1 1 1.19406058765194 -0.44088735923234 0.0724907231239359 1246.40949309846 666.113689916776 1.87116630684199 0.0619900075187454 -311.820480553681 1267.8481698624 -0.24594465486157 0.805840547714919 COL6A1 other 1 1 1 1.87116630684199 -0.24594465486157 0.0169746949890295 221.063902879787 130.507087058123 1.69388427757439 0.0910031001430031 -356.51912255433 257.901234976833 -1.38238625567789 0.167562464782727 IFNAR1 other 1 1 1 1.69388427757439 -1.38238625567789 0.000343770903749649 317.533493013228 290.411172642473 1.09339282688048 0.274830676523899 -1691.56220732498 574.836109060916 -2.9426860641869 0.00342902701891548 SOD1 essential 1 1 1 1.09339282688048 -2.9426860641869 0.70177315759968 320.208246490241 380.420657244694 0.841721500639426 0.400404238852969 310.740866726975 724.074045266652 0.429156201300572 0.668021045539727 COL6A2 other 1 1 1 0.841721500639426 0.429156201300572 0.832550822436832 -18.8173009161374 58.4928230261981 -0.32170273108052 0.747831378226934 -68.8314205174661 113.92206562018 -0.604197440967689 0.546025201811244 SIK1 other 1 1 1 -0.32170273108052 -0.604197440967689 0.0001668681985274 -24.8304977583645 66.8257277955642 -0.371570929003974 0.710392015291178 463.195441183712 131.317097452059 3.52730489914168 0.000464142604408671 TRPM2 other 0.804137848703541 1 1 -0.371570929003974 3.52730489914168 0.0661671236486487 188.374994408609 80.6540077035162 2.33559372649001 0.0199660907421727 142.731443294358 159.384204041762 0.895518123345271 0.371005445855252 TMEM50B other 1 1 1 2.33559372649001 0.895518123345271 0.459652076467336 4063.48360928122 3267.23742879711 1.24370624964873 0.214392969205162 3639.60552808021 6072.0059711912 0.599407435590218 0.549267085350764 APP other 1 1 1 1.24370624964873 0.599407435590218 0.0507474420065153 59.2122826696591 46.317676574318 1.27839492498402 0.201788762309917 -123.958256549954 91.5273152169107 -1.3543307400221 0.176330741266293 DOPEY2 other 1 1 1 1.27839492498402 -1.3543307400221 0.0200682459617071 205.805249894998 151.410130272755 1.35925680484029 0.174772715979642 -466.840067198664 299.692754566279 -1.55772890764171 0.120028092002457 URB1 essential 1 1 1 1.35925680484029 -1.55772890764171 1.59974116815479e-15 354.369128678287 245.095362537625 1.44584183482414 0.148950004744501 -1201.36575478245 286.936164651988 -4.18687465290244 3.43212693834889e-05 AKT1 og 1.29723011325672e-11 0.282464047026114 1 1.44584183482414 -4.18687465290244 1.39724764388724e-17 990.122047487551 162.113989285118 6.10756697712357 2.23393263688032e-09 442.275967121378 197.81045303298 2.2358574096569 0.0258641222445165 EMP3 other 1.16390728735807e-13 1 2.09877971234906e-05 6.10756697712357 2.2358574096569 4.0493824740281e-26 830.603184556851 138.594892290508 5.99302882544783 4.31225079277872e-09 130.874143059312 168.246141793045 0.777873071349816 0.437064773341013 SAE1 essential 3.60557015487462e-22 1 4.03669796712016e-05 5.99302882544783 0.777873071349816 3.58241591453694e-33 3.55201321045177 4.36946992083254 0.812916274698827 0.416707702606506 -28.9189087837141 5.32920584488858 -5.42649498357267 9.53144930500484e-08 NTN5 other 3.28292594408166e-29 0.000865360282401389 1 0.812916274698827 -5.42649498357267 0.000262469633033901 -152.805322446289 112.074374667743 -1.36342783887305 0.173448087617024 -409.23893433334 136.691045679007 -2.99389716641981 0.00291035866009758 LMTK3 other 1 1 1 -1.36342783887305 -2.99389716641981 5.26479952875119e-65 112.155267658106 12.1738526340954 9.21279984480771 1.3520580502709e-18 -10.3214449722604 15.1084532788509 -0.683156957351057 0.494870517822571 GEMIN7 other 5.1205440216634e-61 1 1.32014948028451e-14 9.21279984480771 -0.683156957351057 1.96484131899016e-20 30.9119906537343 21.3694199177276 1.44655263328371 0.148740769818489 -116.567710574016 28.2126493964639 -4.13175341797664 4.31732735791699e-05 WTIP other 1.68465494690216e-16 0.352898338236135 1 1.44655263328371 -4.13175341797664 1.43661826475818e-13 148.196726374306 37.2300682503133 3.9805655304717 8.04653416592365e-05 -103.882250547476 54.5069348087602 -1.90585383147944 0.0573235340598243 CAPN10 other 1.12803266148812e-09 1 0.672207464221262 3.9805655304717 -1.90585383147944 2.76834804363389e-88 379.545311677883 44.020668142868 8.62197980380666 1.22904572033629e-16 -192.569957907563 54.9587298057871 -3.50390117435511 0.000505898166119914 ERVK3-1 other 2.72239346610957e-84 1 1.19586148588721e-12 8.62197980380666 -3.50390117435511 1.49533979534811e-50 169.657065919634 35.8001107287143 4.73900953003356 2.91359153305386e-06 -152.969597733266 44.5238716622601 -3.43567600979608 0.000647846959867608 ZNF787 other 1.42879717445512e-46 1 0.025802766616725 4.73900953003356 -3.43567600979608 0.00149776149075224 -15.9217193282092 21.8432868908939 -0.728906753261876 0.46644826338021 -60.3317957983087 17.0630707217255 -3.53581115511006 0.000449855295749834 SLC47A1 other 1 1 1 -0.728906753261876 -3.53581115511006 3.4152049085306e-06 554.222743009967 109.339920998634 5.06880504346524 5.91699847067665e-07 12.6680726783954 79.6829510583639 0.158980967824807 0.873757147082564 PSMB6 essential 0.0198491709283799 1 0.00533654092070327 5.06880504346524 0.158980967824807 1.28278224511765e-08 -198.800863183709 146.128239149314 -1.36045479190764 0.174387344666939 -728.780140057439 182.749766412709 -3.98785812076834 7.81440997893744e-05 SIGLEC10 other 8.72291926680005e-05 0.626950112610151 1 -1.36045479190764 -3.98785812076834 0.784871353482742 -4.30836025730977 21.755395058388 -0.198036406406173 0.843108668249737 -12.9628269305503 26.7498953332042 -0.484593557061876 0.628207479459605 KLK3 other 1 1 1 -0.198036406406173 -0.484593557061876 9.37771619611936e-40 130.59681126291 21.5682492842674 6.0550492319361 3.02171330862638e-09 -23.7599080679833 26.3415909729544 -0.901992142098712 0.367556776350089 ZNF473 other 8.75034698259897e-36 1 2.8346692548224e-05 6.0550492319361 -0.901992142098712 0.000296841670353694 12.4266342230147 18.2296075280801 0.681673162950617 0.495805917545274 -27.6361709326207 22.2958036288025 -1.23952342749016 0.215815440742435 FAM71E1 other 1 1 1 0.681673162950617 -1.23952342749016 2.71325077347301e-23 2972.18246257515 1306.25631378721 2.27534399734915 0.0233676468318217 -4566.94179280016 1593.88560078547 -2.86528831840226 0.00436682148880844 RPS11 essential 2.37952092833583e-19 1 1 2.27534399734915 -2.86528831840226 2.00102790422123e-18 1105.76726719564 1080.02399049536 1.02383583783955 0.306477942841904 -4522.66285925291 1317.83836662384 -3.43187979178317 0.000656334719429164 RPL13A other 1.68446528977343e-14 1 1 1.02383583783955 -3.43187979178317 1.91071543735757e-23 19.546003636541 6.95576253291105 2.81004469949334 0.00517541350293125 -19.9514779543411 8.60272093002015 -2.31920553004553 0.0208431057819049 CTU1 other 1.676843867825e-19 1 1 2.81004469949334 -2.31920553004553 9.20134969552105e-29 371.602458299546 87.6817105023969 4.23808404478363 2.75060341715139e-05 -165.119453852555 106.988662444679 -1.54333599541853 0.12347143333695 NOSIP other 8.28765567075581e-25 1 0.234653977517185 4.23808404478363 -1.54333599541853 9.39739258476623e-07 -1.2729032700501 79.9441395133612 -0.0159224087944227 0.987303576006783 -244.646350405394 98.9488420327602 -2.4724528895891 0.0137994874039747 IGLON5 other 0.00570703651672853 1 1 -0.0159224087944227 -2.4724528895891 1.38576587518853e-24 106.124321335122 26.6632209778277 3.98017634191201 8.05925621770135e-05 -41.8164125740648 32.5342917301631 -1.28530268680465 0.199365727481231 RCN3 other 1.22363126779147e-20 1 0.673189671864594 3.98017634191201 -1.28530268680465 1.33856412443749e-24 41.2218750951778 32.4123160685881 1.27179665309778 0.20412960389033 -162.170226573609 40.4247718633136 -4.01165471315331 7.10518334703372e-05 ZNF614 other 1.18209740376221e-20 0.571683052102333 1 1.27179665309778 -4.01165471315331 5.22088282985239e-26 -156.560464737288 178.351624609035 -0.877819111995665 0.380524242858308 -1550.01626946536 228.06268677076 -6.79644834239536 3.52706657202159e-11 SLC2A5 other 4.6439752771537e-22 3.35000783010611e-07 1 -0.877819111995665 -6.79644834239536 3.65152434491507e-50 68.3519859556722 157.046439037613 0.43523422991655 0.663608278822879 -1750.70847487383 201.024923900079 -8.70891251148554 6.45054804402271e-17 RERE other 3.48647544452491e-46 6.29637994577056e-13 1 0.43523422991655 -8.70891251148554 1.82613774375562e-25 71.0948799496487 24.1655021736616 2.94199886427919 0.0034340577959388 -103.149570237851 30.8761279123228 -3.34075472581144 0.000907061019248162 MMEL1 other 1.61960156493686e-21 1 1 2.94199886427919 -3.34075472581144 0.859812118778883 -3.45972916724645 13.2318060891221 -0.261470667265196 0.793852472990595 0.59735484586362 16.9067591841788 0.0353323093655122 0.971830856494678 CFAP74 other 1 1 1 -0.261470667265196 0.0353323093655122 9.11816895700519e-15 71.6464606439588 58.4671255352769 1.22541445278903 0.221077625992291 -248.633398497065 74.703545885726 -3.32826769531663 0.0009476510959733 PRDM16 og 7.30182970076976e-11 1 1 1.22541445278903 -3.32826769531663 0.00904195866937577 12.3871239278791 17.7638907609296 0.697320429098997 0.485972246258822 -22.860362728697 22.6981968013931 -1.00714444097577 0.314421425630603 FHAD1 other 1 1 1 0.697320429098997 -1.00714444097577 0.0437030944383435 8.01473250187881 55.1232712751056 0.145396532471366 0.884464840264638 -85.2802236667281 70.464351870094 -1.21026052753523 0.2268331490336 EPHA2 other 1 1 1 0.145396532471366 -1.21026052753523 1.02556846538767e-06 32.9085774458277 7.72422147075788 4.26043939449586 2.50040177917658e-05 18.7535551635737 9.87391072858595 1.89930369830874 0.0581827793393726 ARHGEF19 other 0.00621186819485313 1 0.21368433604843 4.26043939449586 1.89930369830874 0.00812472513265992 90.8730502668653 209.512899103232 0.433734871007108 0.664694529666204 -341.45469608859 267.709652140797 -1.27546651141666 0.202820226004033 EFHD2 other 1 1 1 0.433734871007108 -1.27546651141666 1.13992963141781e-68 97.168544135813 23.7592662900445 4.08971148139066 5.14037214271708e-05 -230.47534041687 30.3592658000606 -7.59159796336082 1.9224910523087e-13 PEX14 other 1.11200135544807e-64 1.85405037084651e-09 0.433024949302486 4.08971148139066 -7.59159796336082 4.19774703969072e-59 388.962358884033 134.682490731803 2.88799499304319 0.00406917356766582 -1306.99749874631 172.095446249294 -7.59460826670002 1.88341260784326e-13 PGD essential 4.05796206326901e-55 1.81673980152561e-09 1 2.88799499304319 -7.59460826670002 1.07495102932063e-29 569.500945530155 196.443694958196 2.89905433539797 0.00393100104148607 -1016.34819191301 252.221749141986 -4.02958188724982 6.58796961851304e-05 SH3BGRL3 other 9.71648235402921e-26 0.531253870036892 1 2.89905433539797 -4.02958188724982 8.92099325727447e-11 7.06476620330482 10.3149327263017 0.684906667911718 0.493765094045855 -41.4634438541409 13.243745873663 -3.13079428204648 0.00186004376774037 CNKSR1 other 6.57566412993701e-07 1 1 0.684906667911718 -3.13079428204648 5.24152735021625e-36 4156.74119973163 804.914242531299 5.1642038121471 3.67585532429815e-07 -2638.51595391598 1028.92588010447 -2.56434015795975 0.0106703911085189 RPL11 essential 4.84317127159982e-32 1 0.00332995733828169 5.1642038121471 -2.56434015795975 4.72051830201991e-17 214.138896289449 31.7207568187349 6.75074991158388 4.68307689815789e-11 101.327436394378 40.7275212911846 2.48793526298666 0.0132195587475432 ZNF593 other 3.91094941322349e-13 1 4.46671874546299e-07 6.75074991158388 2.48793526298666 0.842258039071899 50.1466138158195 124.842947152768 0.401677587396715 0.688117236005987 91.0137932302569 160.310507904826 0.567734420031222 0.570506208811277 C1orf216 other 1 1 1 0.401677587396715 0.567734420031222 7.13848931061535e-56 138.694683919365 86.9578508043944 1.59496448723588 0.111441451159659 -954.382412996618 111.662352953796 -8.54703835044137 2.12149729077237e-16 KIAA0319L other 6.87436520612258e-52 2.06909630769029e-12 1 1.59496448723588 -8.54703835044137 7.22575551516721e-09 58.4598969250893 16.8206992050872 3.47547365375923 0.000560796950294897 3.25221569029208 21.5994166621373 0.150569607557645 0.880384553113073 EVA1B other 4.96770691667746e-05 1 1 3.47547365375923 0.150569607557645 5.93935636478288e-18 19.7626802198939 12.8157877636384 1.54205738924342 0.123783440858873 -59.6446426719223 16.4635492710609 -3.6228301498003 0.000325627011514549 C1orf94 other 4.96530192095849e-14 1 1 1.54205738924342 -3.6228301498003 3.75478067224345e-06 -13.2270815974569 43.2182000804798 -0.306053504607452 0.759709992218513 -164.758007634623 55.5401996266538 -2.96646408803247 0.00317806699906288 DMRTA2 other 0.0217627087763231 1 1 -0.306053504607452 -2.96646408803247 4.33318361894543e-08 133.636399474375 23.4252752028027 5.70479528276307 2.14711348903752e-08 162.073700018773 32.9295817404005 4.92182686365338 1.21618887599036e-06 PLK4 essential 0.000285296809471367 0.0106951649754592 0.000198736824545313 5.70479528276307 4.92182686365338 8.19692323500561e-09 57.781855135241 50.178040584632 1.15153669736833 0.250142574668748 -148.138471704704 64.4804823211323 -2.29741568878051 0.0220679527619922 MAP3K6 other 5.62390903153735e-05 1 1 1.15153669736833 -2.29741568878051 1.37593153179725e-92 91.1612097110092 27.8352014069614 3.27503323501048 0.00114095541722118 -404.294682323223 35.611882757789 -11.3528028010481 2.43740303472897e-26 GPN2 essential 1.35405422044167e-88 2.39889206678025e-22 1 3.27503323501048 -11.3528028010481 0.038153481702187 3.00550577044514 3.64953799588011 0.823530478059961 0.410657655655626 -2.78126183982477 4.66915677487697 -0.595666835345886 0.551707600978645 SYTL1 other 1 1 1 0.823530478059961 -0.595666835345886 1.54455977497776e-56 177.8446373151 68.1681919996786 2.6089094062512 0.00939602415903439 -667.613822197737 87.2132242124133 -7.65496091019088 1.26101392142704e-13 WDTC1 other 1.48911007905606e-52 1.21725673835352e-09 1 2.6089094062512 -7.65496091019088 2.40159258786449e-14 41.756663117208 16.8309211362408 2.48094936570622 0.0134785897509746 -45.0891420700226 21.6196883757961 -2.08555929605819 0.0375981681704263 NBPF3 other 1.91166769994014e-10 1 1 2.48094936570622 -2.08555929605819 0.00477622924319227 -95.1068360964974 311.450334080904 -0.305367584135555 0.760231938826639 -803.817399614227 400.234556746882 -2.00836580965841 0.0452206417727414 HSPG2 other 1 1 1 -0.305367584135555 -2.00836580965841 1.08257694250154e-38 76.2154959101009 17.7882168588019 4.28460573170874 2.25228191341829e-05 -88.7561365996486 22.8418035971726 -3.88568863321437 0.000117818706732507 ITGB3BP other 1.00722958730344e-34 0.930885601893537 0.192840377426874 4.28460573170874 -3.88568863321437 6.37357310266494e-78 657.406511390415 162.772615371175 4.03880290238816 6.34326810552815e-05 -1870.85846687805 209.02812827162 -8.95027134552428 1.01389356337545e-17 SERBP1 essential 6.24992578447324e-74 9.92196241119213e-14 0.532327059415923 4.03880290238816 -8.95027134552428 1.10781142131601e-53 48.4280138611193 11.4147470367227 4.24258318693529 2.69815850437064e-05 -86.3790493012462 14.7281841296646 -5.86488113814837 8.86504209262545e-09 BCL10 other 1.06416365131616e-49 8.19041238937665e-05 0.230233865177946 4.24258318693529 -5.86488113814837 8.44504252612748e-07 499.32106758936 433.763508549126 1.151136639547 0.250304036724486 -1036.59239710346 559.675024079648 -1.85213267075492 0.064679426237056 CYR61 other 0.00514218639415902 1 1 1.151136639547 -1.85213267075492 0.608531066558696 -200.289312883521 351.630092544312 -0.569602309729169 0.569239469856421 -18.18254358794 453.700176785567 -0.0400761218934541 0.968050699088085 PRKACB other 1 1 1 -0.569602309729169 -0.0400761218934541 5.60876637176884e-30 107.959858503727 37.5060427548398 2.87846572376116 0.00419176175834574 -198.495029030951 48.1642314221107 -4.12121242611229 4.50829595692625e-05 PIGK other 5.07649444308797e-26 0.368147447842597 1 2.87846572376116 -4.12121242611229 0.182749153837672 -46.2300178088285 36.8842941270459 -1.25337949127051 0.210737795423006 -15.7280918886332 47.3826818053147 -0.33193756219322 0.74009554945306 TINAGL1 other 1 1 1 -1.25337949127051 -0.33193756219322 7.17269407748881e-17 -9.03066112245713 41.0031682816833 -0.220243008062654 0.825784990407185 -263.819892269109 52.6959154650686 -5.00645808960262 8.06258357672511e-07 AZIN2 other 5.9311007326755e-13 0.00713458020704405 1 -0.220243008062654 -5.00645808960262 8.93180867107499e-25 3632.12982367992 839.348699475196 4.32731929643891 1.87166898457438e-05 -2080.53070320836 1082.99221656816 -1.92109478847526 0.0553685054927116 RPS8 essential 7.8966120460974e-21 1 0.160701499015556 4.32731929643891 -1.92109478847526 9.21459174627129e-18 305.413687423813 53.0290017213658 5.75937086329799 1.59164983622475e-08 65.0449139636794 68.4220945984988 0.950641957767637 0.342310421257876 KIF2C other 7.68957681226339e-14 1 0.000147673271804932 5.75937086329799 0.950641957767637 1.79760647181855e-45 -695.352942293675 332.494068724029 -2.09132435042268 0.0370745387121249 -4467.13715567342 429.00940778052 -10.4126787773353 7.79991327418588e-23 PTPRF other 1.70053572234035e-41 7.6665347571973e-19 1 -2.09132435042268 -10.4126787773353 0.00794697063011492 10.4703810944552 5.54665343451939 1.88769340252866 0.0597279349708089 1.79736400459966 7.15671865738452 0.251143588374134 0.801820875073649 BEST4 other 1 1 1 1.88769340252866 0.251143588374134 3.16583255623774e-30 45.940117259531 32.4446975311854 1.41595147297564 0.157500420046841 -229.87255118284 41.6621527980922 -5.51753895908534 5.89242218682981e-08 MOB3C other 2.86666137967327e-26 0.000537271054995142 1 1.41595147297564 -5.51753895908534 0.0376754083928405 8.83962710208196 4.55995991221656 1.93853175735159 0.0532004872824247 14.8783012077942 5.85543281558836 2.54093961563099 0.0113995222791481 CYP4B1 other 1 1 1 1.93853175735159 2.54093961563099 4.2862685105931e-09 323.875407045204 237.527466970384 1.36352823181324 0.173416491223978 -669.176304530245 306.476197688656 -2.18345277570315 0.0295324902528436 LMO4 other 2.97166995839419e-05 1 1 1.36352823181324 -2.18345277570315 1.58938988672036e-24 -10.4024730753888 8.00624200229288 -1.29929535884747 0.194526070633072 -77.8487228353204 10.6481641137154 -7.31099953043054 1.26967077029093e-12 SYPL2 other 1.40279551401939e-20 1.21989967609553e-08 1 -1.29929535884747 -7.31099953043054 7.5017034587615e-62 97.7821874309397 24.4942791417717 3.99204185046562 7.67983843132863e-05 -224.009755862197 31.6026582269552 -7.08832004742975 5.46770165516236e-12 MTF2 other 7.2751520143069e-58 5.22766955250073e-08 0.642341686396326 3.99204185046562 -7.08832004742975 1.30235730511837e-11 5.9467854219975 31.5322232502618 0.18859391470115 0.85049845224955 -152.909941571963 40.685298461146 -3.75835860508655 0.00019419286994682 SLC44A3 other 9.79372693449014e-08 1 1 0.18859391470115 -3.75835860508655 2.30096919124292e-12 -6.75396591255615 199.621402195465 -0.0338338767200063 0.973025034488164 -983.806614738229 250.860568932478 -3.92172679399062 0.000102023900884326 IGSF3 other 1.75886084978609e-08 0.811090012030391 1 -0.0338338767200063 -3.92172679399062 2.95034378764509e-07 14.7896440648088 13.9487101140119 1.06028757812897 0.289602136412106 -33.6618375294477 17.5497142710048 -1.9180846485383 0.0557546336120083 ZNF697 other 0.00184986555485347 1 1 1.06028757812897 -1.9180846485383 1.85186906416094e-42 37.8679333007617 56.4526831715615 0.670790672352628 0.502707447068114 -561.128229846893 72.4907455184391 -7.74068780550977 6.90294839231667e-14 CTTNBP2NL other 1.7398309857792e-38 6.67169962117406e-10 1 0.670790672352628 -7.74068780550977 2.6226694021383e-43 56.2198015656114 59.0334471511349 0.95233811133678 0.341450772108797 -581.021412838051 76.1652891876612 -7.62842784469039 1.49474506822153e-13 STRIP1 essential 2.46976777599363e-39 1.44242899083378e-09 1 0.95233811133678 -7.62842784469039 1.65662260801e-70 250.725269246113 43.9888162566673 5.69975031342452 2.20710196816482e-08 -416.305746871723 58.5043687831221 -7.11580614458015 4.5744108692935e-12 PSMA5 essential 1.61802330124337e-66 4.37771120191388e-08 0.00020420107409461 5.69975031342452 -7.11580614458015 0.00251629016608069 30.0693479056155 10.2065777781624 2.94607541912341 0.0033903983502401 20.3973614413756 12.7530345605785 1.59941238647834 0.110451701459115 FNDC7 other 1 1 1 2.94607541912341 1.59941238647834 1.20759832878659e-23 56.9717253226999 47.6223378427219 1.19632357216177 0.232217497245461 -293.6868070769 61.1517217535719 -4.80259261154401 2.15396172190652e-06 C1orf162 other 1.06111665150477e-19 0.0187739303681372 1 1.19632357216177 -4.80259261154401 1.24395833881016e-24 -75.8057180742757 139.656653496289 -0.542800619780639 0.58754317867661 -1163.9372951284 180.18580845014 -6.45965020852614 2.79594205047963e-10 CD53 other 1.09916158817266e-20 2.63517538257705e-06 1 -0.542800619780639 -6.45965020852614 1.46073521445887e-18 4.8609892301596 343.882605326509 0.0141356066136122 0.988728229667005 -2440.9064367918 457.357948500683 -5.33697171940186 1.51973361977731e-07 CELSR2 other 1.23125371226738e-14 0.00137216748529693 1 0.0141356066136122 -5.33697171940186 9.12803032553731e-06 28.1632046809947 7.35933591585611 3.82686766890413 0.000148666857369215 -35.2586924721502 17.4095940024473 -2.02524495787746 0.0434482058150879 TAF1A other 0.0509800493681259 1 1 3.82686766890413 -2.02524495787746 0.195921833572644 -35.6710250928314 106.745344594822 -0.334169375050777 0.738411694596438 -456.069989872847 252.521848750398 -1.80606150370633 0.0715950618471756 SUSD4 other 1 1 1 -0.334169375050777 -1.80606150370633 0.594968865777589 176.671002588049 176.414043773668 1.00145656665923 0.317159060699997 22.4906267581845 417.333427030046 0.0538912660752796 0.957046366544767 TP53BP2 other 1 1 1 1.00145656665923 0.0538912660752796 5.71411084496837e-08 342.927929648575 80.0802260448948 4.28230471597722 2.27685814056824e-05 -368.826106091808 158.247520495827 -2.33069121674822 0.0202248724612648 SCCPDH other 0.000373131438176435 1 0.194921825414047 4.28230471597722 -2.33069121674822 0.189749038618265 168.165481067154 111.422771298835 1.50925595465703 0.13195438719002 -129.128485720584 242.059469047182 -0.53345769214843 0.59398738078239 LYST other 1 1 1 1.50925595465703 -0.53345769214843 0.723632233129589 -3.79142281249612 5.17528700072443 -0.732601459970316 0.464193395432809 -6.02535379102557 11.6123480260404 -0.518874716595977 0.604110163630317 MAP3K21 other 1 1 1 -0.732601459970316 -0.518874716595977 4.14530807716015e-08 140.632728271568 26.9224925536702 5.22361471513885 2.7186541425365e-07 -94.6615560693114 63.1668024968899 -1.4985966097298 0.134698665915872 NVL essential 0.000273134349204082 1 0.00246908169225165 5.22361471513885 -1.4985966097298 0.00576467276909457 221.869494767638 95.2710183459951 2.32882463753957 0.0203224833634432 -363.926701924158 225.377638494511 -1.61474183665751 0.107086715501518 DEGS1 other 1 1 1 2.32882463753957 -1.61474183665751 0.00373254902385948 760.818138854505 232.019079505115 3.2791188572823 0.00112437452181623 28.3666704174635 548.875336197466 0.0516814448504535 0.958806083386461 FBXO28 other 1 1 1 3.2791188572823 0.0516814448504535 7.5343767706186e-06 138.004097328724 31.0360906357521 4.44656831778128 1.10732977981461e-05 -71.4081259871362 72.818317381125 -0.980634111790747 0.327314546198495 CNIH4 other 0.0423808693347296 1 0.0960387118033208 4.44656831778128 -0.980634111790747 0.00165453670885867 120.263921941933 43.3876721688253 2.77184545586995 0.00581371161707804 -80.6596382674909 90.2409590311709 -0.893825144739758 0.371910836495474 SUMF1 other 1 1 1 2.77184545586995 -0.893825144739758 0.08252369071762 -12.9584604552922 7.91972760448506 -1.63622552472053 0.102510710542761 -39.7537197840882 18.9728510182469 -2.09529499524639 0.036718421127411 NYAP2 other 1 1 1 -1.63622552472053 -2.09529499524639 8.16802928065636e-05 62.5654784417544 27.3005297130993 2.29173129969469 0.0223948698060831 -128.929516965637 59.6555061362293 -2.16123414779541 0.0312185065094194 RHBDD1 other 0.409136586668077 1 1 2.29173129969469 -2.16123414779541 0.000133959976620404 47.4309086485835 112.200454633233 0.422733658287109 0.67269705263957 -466.320610247184 169.680981407923 -2.74821966715363 0.00623949667416287 ACKR3 other 0.653456765954331 1 1 0.422733658287109 -2.74821966715363 0.695159928845523 -36.9656636738646 87.5888930417829 -0.42203597271438 0.673206306717515 -111.129910485588 134.164331617889 -0.828311885472625 0.407946036559575 TRPM8 other 1 1 1 -0.42203597271438 -0.828311885472625 0.000174441069138832 1434.20974446754 1057.54538152519 1.35616851013913 0.175749070441628 -3102.68344606986 1609.75562628739 -1.92742512925743 0.054577493899726 HES6 other 0.838363778281228 1 1 1.35616851013913 -1.92742512925743 1.95108208903647e-10 36.6584928968504 18.0302575877841 2.03316523451596 0.0426382906392532 -81.1980206637094 26.3973213348658 -3.07599470543484 0.00222944857082848 ANKMY1 other 1.42350949216101e-06 1 1 2.03316523451596 -3.07599470543484 3.93419581755861e-18 99.4435329027753 38.0557290558733 2.61310281972979 0.00928116154788839 -320.337448311977 62.0028487776577 -5.16649564700981 3.63029699323267e-07 COPS7B other 3.29685609511411e-14 0.00324984186834188 1 2.61310281972979 -5.16649564700981 1.04935925837827e-19 44.3611795052174 26.8958982011287 1.64936598039904 0.0997896392532221 -262.289658811116 42.7038365522955 -6.14206310222066 1.82983749340647e-09 DIS3L2 other 8.93529408509097e-16 1.70705539759889e-05 1 1.64936598039904 -6.14206310222066 0.263646726979853 -19.2009310901514 16.0228455746805 -1.198347135074 0.231429902491325 -55.7642072593334 37.6093893827342 -1.48272035719181 0.1388678583461 CPNE9 other 1 1 1 -1.198347135074 -1.48272035719181 0.0416758672358527 99.615107688585 40.0669238821449 2.48621800819046 0.0132826113253482 47.3031048853039 94.0464997074658 0.502975709169841 0.615234169452207 FANCD2 other 1 1 1 2.48621800819046 0.502975709169841 1.05845402992942e-07 30.4691302345224 9.14549283236517 3.33160069041819 0.000936654844768471 -60.6283921237479 20.2037541969372 -3.00084783910799 0.0028460673409482 TAMM41 essential 0.00068100932285659 1 1 3.33160069041819 -3.00084783910799 2.38943368305174e-09 937.062585969747 154.071967666418 6.08197974078313 2.59317145456171e-09 155.633088369677 340.372949468918 0.45724282323995 0.647723743138519 VGLL4 other 1.67690455876571e-05 1 2.43446936154253e-05 6.08197974078313 0.45724282323995 7.92996598527683e-05 13.8771316261086 112.778576204328 0.123047586635307 0.902125856206512 -908.086536794033 232.36612075482 -3.9079988676671 0.000107788188696892 RAB5A other 0.397925693141191 0.854544759988957 1 0.123047586635307 -3.9079988676671 0.45282736921773 -26.3915654919273 27.9146310937342 -0.945438447791316 0.344956335184582 -68.6790780050819 59.91972281969 -1.14618484153791 0.252344477666142 GRIP2 other 1 1 1 -0.945438447791316 -1.14618484153791 0.00206842762211039 -15.2807566929329 73.5460914627812 -0.207771159405064 0.835504222950526 -522.806709617801 157.869233525733 -3.31164406098533 0.00100430999646368 EAF1 other 1 1 1 -0.207771159405064 -3.31164406098533 0.290466278237906 -57.590512540894 40.4137642541871 -1.42502223199679 0.15487282427775 -102.26990185387 84.0590862829325 -1.21664303499139 0.224404345011161 CNTN4 other 1 1 1 -1.42502223199679 -1.21664303499139 0.000264116082428594 32.0975051348248 41.6568130204843 0.770522342144637 0.4414074199626 -242.926228118111 77.4202561161389 -3.13776058495202 0.00181789641989555 DYNC1LI1 other 1 1 1 0.770522342144637 -3.13776058495202 0.00246441347597495 62.4394550588562 48.4086004879583 1.289842185675 0.19778762416012 -201.11672595255 90.8803656354246 -2.21298323951896 0.0274148484677533 RBMS3 other 1 1 1 1.289842185675 -2.21298323951896 0.240227947835141 -41.6511899602407 28.893511211075 -1.44154130856466 0.150149657613902 3.73873636209464 53.6993321346009 0.0696235169689495 0.94452523917667 OSBPL10 other 1 1 1 -1.44154130856466 0.0696235169689495 1.81091673163457e-06 222.542816424581 114.124727004057 1.94999648425594 0.0518141580798294 -500.884395653635 183.433044573109 -2.73061157993266 0.00657677939949273 POMGNT2 other 0.0107604672193726 1 1 1.94999648425594 -2.73061157993266 0.00888442967808249 4.60557235851276 4.14160020090663 1.11202726847091 0.266736416041924 -11.0149546320154 6.65680746145308 -1.65469028446423 0.0987036933078132 ACKR2 other 1 1 1 1.11202726847091 -1.65469028446423 0.00161400174240606 215.887619332113 70.592470227872 3.05822446268319 0.00236301760622755 31.2965721967064 113.463506794411 0.275829410538261 0.782809181914778 FAM198A other 1 1 1 3.05822446268319 0.275829410538261 0.349444989939401 -180.254089685826 190.286433240837 -0.947277673010385 0.344020817059087 -466.147062380937 323.719384041716 -1.43997265953301 0.150591119675185 CSRNP1 other 1 1 1 -0.947277673010385 -1.43997265953301 1.68762607285243e-11 122.712028132626 36.4686113028356 3.36486703904419 0.000833377161809532 -208.478240275586 61.0696871682422 -3.41377612924796 0.000700446674018261 SLC25A38 other 1.26622584246118e-07 1 1 3.36486703904419 -3.41377612924796 0.978042763698902 5.10458802769114 39.6733693076507 0.12866535201755 0.897681510427628 -4.62549205918269 67.4899833998117 -0.0685359786174668 0.945390256879059 ITGA9 other 1 1 1 0.12866535201755 -0.0685359786174668 4.79268635660098e-05 -111.407867092812 131.394426917391 -0.847888831410295 0.396962979969121 -964.510910552503 229.624930114489 -4.2003754125112 3.23005138562296e-05 GOLGA4 other 0.247062981682781 0.266317736744613 1 -0.847888831410295 -4.2003754125112 0.00518819717003206 116.806705578933 79.4396272195403 1.47038335484788 0.142175935797927 -219.384266171968 135.137983385246 -1.62340935299113 0.105221371593989 CTDSPL other 1 1 1 1.47038335484788 -1.62340935299113 0.227850834037314 -26.2816046515459 45.2243327807486 -0.581138582606876 0.561445973539826 87.3292401706439 80.5271057205932 1.08447012206861 0.278752970041754 STAC other 1 1 1 -0.581138582606876 1.08447012206861 0.0787359007353537 -491.45432377628 291.566230353483 -1.68556668301559 0.0925915088422924 -1291.80109345722 625.857015544944 -2.06405147081787 0.0396012078361675 IQSEC1 other 1 1 1 -1.68556668301559 -2.06405147081787 3.07317030070612e-05 36.5335865910313 31.7890023209156 1.14925238049997 0.251079098844341 -246.282512384814 68.2361948967795 -3.6092650353286 0.000342526479648973 CAND2 other 0.162447782095325 1 1 1.14925238049997 -3.6092650353286 3.08895695141317e-05 3303.60974357656 868.62609227298 3.80325870125756 0.000163076789356406 -1545.33395621038 1864.53600293612 -0.828803495227183 0.407667023210608 RPL32 essential 0.163251374882186 1 1 3.80325870125756 -0.828803495227183 0.000539687073145262 -171.218961777116 180.558319027429 -0.948275120744258 0.343512306972285 -1132.30654816957 306.114589198167 -3.69896302928756 0.00024401065363984 PTPRG other 1 1 1 -0.948275120744258 -3.69896302928756 0.0315565594430156 186.89116580402 196.251935849705 0.952302279184376 0.341471326220328 -511.604849594503 323.75993105492 -1.58019816697984 0.114786650932491 IL17RD other 1 1 1 0.952302279184376 -1.58019816697984 0.00253766979507054 24.0887249736572 11.7886166873739 2.04338860211285 0.0416132058357218 -25.3393396557775 19.446932738024 -1.30299929542268 0.193261151521751 SHQ1 essential 1 1 1 2.04338860211285 -1.30299929542268 0.000182931036504182 -456.004851430202 467.891956171856 -0.974594338319234 0.330299458315527 -3130.94802159181 793.253696224964 -3.94696934472762 9.21786104165864e-05 SLC25A26 essential 0.87623966485503 0.736046204176442 1 -0.974594338319234 -3.94696934472762 2.83730343600825e-10 87.9290750725887 56.5254352241125 1.55556652901418 0.120535090640396 -435.585026959763 94.2447710124224 -4.62184821800191 5.01370656682293e-06 UBA3 essential 2.05959856419839e-06 0.0430526982893085 1 1.55556652901418 -4.62184821800191 2.59803297624663e-06 563.381440832076 249.61584904877 2.25699386869462 0.0245015608436964 -1071.91428708165 416.184120323898 -2.575577093733 0.0103349355194064 ARL6IP5 other 0.0152686398014014 1 1 2.25699386869462 -2.575577093733 0.00168182431130855 27.9808794041826 57.6998576414937 0.484938447821416 0.627962446215546 -258.58991374646 96.1982522698278 -2.68809367784705 0.00746001695975571 TMF1 other 1 1 1 0.484938447821416 -2.68809367784705 0.000372742640217018 -2084.85993071786 2133.62827210357 -0.97714300001395 0.329037736411735 -13717.7901357055 3617.30628383485 -3.79226669220908 0.000170226816479211 LRIG1 other 1 1 1 -0.97714300001395 -3.79226669220908 0.0512180950809149 338.901949374458 178.309584057756 1.90063787746084 0.0580057020595575 -17.8870955392544 280.609471447154 -0.0637437341191919 0.949203360954431 LIMD1 other 1 1 1 1.90063787746084 -0.0637437341191919 0.00121762698918578 25.0894384637769 25.4810365903464 0.98463178194572 0.32534855575562 -89.1136701223527 40.1000330258563 -2.22228420771855 0.0267741617743294 ZNF660 other 1 1 1 0.98463178194572 -2.22228420771855 0.820310694726537 -14.7414792364542 27.399802978542 -0.538014059736084 0.590840612511719 -29.2913276971336 54.9397743540435 -0.533153403732132 0.594197805517576 NFKBIZ other 1 1 1 -0.538014059736084 -0.533153403732132 0.903597439671478 -47.6098829648896 146.629325924702 -0.324695504563245 0.745567266931115 -120.433810143044 281.219578287837 -0.428255425444726 0.668676642296933 COL8A1 other 1 1 1 -0.324695504563245 -0.428255425444726 0.000819010168779074 -26.5514258875242 77.315412408655 -0.34341698582923 0.731449560604918 -548.606006628735 155.026345085324 -3.53879210870122 0.000444946632673417 NXPE3 other 1 1 1 -0.34341698582923 -3.53879210870122 0.00047952632233938 -28.0095450871002 23.2371613492556 -1.20537722599226 0.22870999703293 -181.610081637366 46.5945182666707 -3.89767054995551 0.000112363399978719 MYH15 other 1 0.888794493831667 1 -1.20537722599226 -3.89767054995551 0.0297363566374029 64.5744459833799 27.844906068774 2.31907573413563 0.020850209862013 121.666007123072 54.4176495832938 2.2357821047902 0.0258690962176044 PHLDB2 other 1 1 1 2.31907573413563 2.2357821047902 2.78044040790657e-09 81.3892543859649 42.9874871328242 1.8933243093388 0.0589735949307618 -382.382832080203 84.0109859046608 -4.55158129573848 6.90684108140091e-06 ABHD10 other 1.9463082855346e-05 0.0589291681065125 1 1.8933243093388 -4.55158129573848 0.402753803931638 -412.474953831954 310.573001615556 -1.32810949981588 0.184833577552828 -505.067405355504 606.956716973805 -0.832130844310767 0.405788548148259 TAGLN3 other 1 1 1 -1.32810949981588 -0.832130844310767 0.514256983921327 -9.28840079935111 9.53439799476442 -0.974198979783686 0.330495462811545 -18.7772329945306 18.9372528701746 -0.991549995306025 0.321964538437095 PLA1A other 1 1 1 -0.974198979783686 -0.991549995306025 0.159928987167927 3.75338840578379 39.515464087854 0.094985304928697 0.924369938017161 -130.902654987561 78.4857456259863 -1.66785260104887 0.0960597124376572 RABL3 other 1 1 1 0.094985304928697 -1.66785260104887 0.761968552485473 9.98206444654906 23.4226650070682 0.426171165558521 0.670192482741627 -16.0645824931238 46.5221748007385 -0.345310221672371 0.730026934239351 ADPRH other 1 1 1 0.426171165558521 -0.345310221672371 0.00273551039074516 128.57240607398 111.726928557479 1.15077365621695 0.250453214030957 -531.032862211627 221.912395482415 -2.39298422720919 0.0171322044235538 IGSF11 other 1 1 1 1.15077365621695 -2.39298422720919 6.70566335835448e-09 43.2995750708205 44.6663427031136 0.96940050271459 0.332880394454763 -434.111392148931 86.4815304488674 -5.01970062157493 7.5419461346961e-07 ATG3 other 4.61886092123457e-05 0.00667914749688686 1 0.96940050271459 -5.01970062157493 0.103622763471865 280.916815827516 199.341343032992 1.40922505865239 0.159478194543955 -315.29750905161 395.932435647109 -0.796341700412319 0.426264859681485 BOC other 1 1 1 1.40922505865239 -0.796341700412319 0.0854235977551038 3.3356072185141 91.5270831366351 0.0364439366382361 0.970945060516315 -388.314085753355 192.972426724804 -2.01227756910124 0.0448051854518619 SRPRB essential 1 1 1 0.0364439366382361 -2.01227756910124 0.0281054181197962 22.8765889830569 142.837106650267 0.160158585675287 0.8728301554175 -715.517270159216 301.146203814686 -2.37597971050473 0.0179326177252211 TMEM108 other 1 1 1 0.160158585675287 -2.37597971050473 0.0103420306844291 -17.6852559205511 31.6397885763816 -0.558956197758942 0.576477931031741 -205.244461420933 69.1023413128981 -2.97015206028372 0.00314053552415098 MED12L other 1 1 1 -0.558956197758942 -2.97015206028372 0.00108949914017308 10.9238624581047 137.713624101588 0.0793230337910973 0.936812079327599 -1010.36166236648 297.718244712579 -3.39368406307076 0.000752611713693321 EIF2A other 1 1 1 0.0793230337910973 -3.39368406307076 0.475810397765249 195.409602543709 698.06245155295 0.279931404574175 0.779662587092488 -1294.51905518965 1386.53463298449 -0.933636293240813 0.351007108140125 ALDH1L1 other 1 1 1 0.279931404574175 -0.933636293240813 0.0339551141482335 -318.985877640031 302.208615113691 -1.05551550050957 0.291772811250564 -1524.04554904796 585.145960507675 -2.60455621658175 0.0095128800098124 OSBPL11 other 1 1 1 -1.05551550050957 -2.60455621658175 0.00191299703190056 11.0221015852174 30.7233747634236 0.35875295829608 0.719952767525736 -209.844350905168 67.099720970993 -3.12735057416831 0.00188148381992834 TRPC1 other 1 1 1 0.35875295829608 -3.12735057416831 0.343142848958893 3.69655286026119 3.29477041656375 1.12194550542203 0.262501694959975 -3.4732465713932 8.67810371247686 -0.400231051214515 0.689181920040403 FAM86B2 other 1 1 1 1.12194550542203 -0.400231051214515 0.161671526835518 114.866427062879 111.181596182519 1.03314245348943 0.302111272712649 -223.190133017153 227.460222228998 -0.981227094698142 0.327026172368221 LPP other 1 1 1 1.03314245348943 -0.981227094698142 7.16347302547009e-05 69.4073297250848 16.0125984953497 4.33454506120552 1.81369137371294e-05 45.2111951217019 29.297994950648 1.54314980249875 0.123516589930104 TMEM44 other 0.361683753055985 1 0.155832362829416 4.33454506120552 1.54314980249875 0.00121156955345904 -64.7925664725987 53.2796604784092 -1.21608444743853 0.224609226903885 -293.867934097592 83.0776999526404 -3.53726612875796 0.000447555121005273 AMT other 1 1 1 -1.21608444743853 -3.53726612875796 4.45920976719802e-05 -97.1523437968917 95.3983234872639 -1.01838628023544 0.309057886681949 -620.278398655544 148.752323560161 -4.1698736786769 3.67667681026465e-05 TCTA other 0.230897881745514 0.302112533499446 1 -1.01838628023544 -4.1698736786769 1.30849945504208e-08 16.1132765140143 65.0491602476808 0.247709216424339 0.804475745732893 -490.118264209833 101.429599376257 -4.83210292876855 1.87319060017959e-06 NICN1 other 8.89517929537607e-05 0.0163623198925687 1 0.247709216424339 -4.83210292876855 4.8523414842925e-06 91.5627840909079 66.068589358623 1.38587466419029 0.166491975320463 -304.99443063447 100.953923055529 -3.02112509750324 0.00266621501127104 DCAF1 other 0.0278475877783546 1 1 1.38587466419029 -3.02112509750324 0.00333641154040359 145.886784641812 72.695559998062 2.00681836202515 0.0453858887710959 -115.340282497743 112.277615939521 -1.02727762370615 0.304859326469068 MANF other 1 1 1 2.00681836202515 -1.02727762370615 0.555298536100507 -86.747805636241 81.5845433857019 -1.06328726050631 0.288237561827149 -109.184367338984 162.043490238309 -0.673796689878824 0.500795991135319 STXBP5L other 1 1 1 -1.06328726050631 -0.673796689878824 0.435864958892131 -13.5344664778094 14.3045807589483 -0.946163100190326 0.344587076884293 -33.7256171590452 27.6960673652163 -1.21770418573582 0.223992002370393 EAF2 other 1 1 1 -0.946163100190326 -1.21770418573582 0.00276848885394156 33.8778059442124 11.0114588563824 3.07659560700046 0.00222505571767277 7.59963901180599 19.3011570535191 0.393740074272924 0.693964555018654 MUC4 other 1 1 1 3.07659560700046 0.393740074272924 0.720601104328404 57.4601096762774 97.6204411084248 0.588607355425261 0.55642949616191 -21.705804401328 158.929251986896 -0.136575263080693 0.891429570264773 SLIT2 other 1 1 1 0.588607355425261 -0.136575263080693 1.46611024803816e-05 -16.2764441259619 39.192498110441 -0.415294888325218 0.67813222822778 -248.161447509855 60.9458636985247 -4.0718341237629 5.54854276623232e-05 DGKQ other 0.0801962305676871 0.44970939120313 1 -0.415294888325218 -4.0718341237629 0.000168779784132476 395.73185329824 109.561124263201 3.61197327938662 0.000341003107103983 10.5107818999907 188.865620158718 0.0556521715871725 0.955645620212969 FIP1L1 essential 0.812674660597874 1 1 3.61197327938662 0.0556521715871725 0.0416270306418037 -19.4675478057783 15.6352162913116 -1.24510895423918 0.213766669724949 -61.0618894064259 24.3133713574991 -2.51145299878753 0.0123874041699572 SLC26A1 other 1 1 1 -1.24510895423918 -2.51145299878753 6.23569952754513e-06 64.1127895155589 19.1923276092739 3.34054268042919 0.000907736583654024 -33.7841893564356 30.7601817833355 -1.09830915806676 0.272672892121736 LYAR other 0.0353875948188186 1 1 3.34054268042919 -1.09830915806676 1.34558206751493e-08 57.5938297450644 25.0911775599193 2.29538169771134 0.0221852222591327 -82.993254961227 34.4259513681149 -2.41077593103483 0.016331413070003 CENPC essential 9.1405389846289e-05 1 1 2.29538169771134 -2.41077593103483 0.36990187712923 -22.2689720273872 62.7081025188388 -0.35512112682244 0.722671364070277 -112.05525218368 89.8252510630877 -1.24748053423174 0.212894060370537 EPHA5 other 1 1 1 -0.35512112682244 -1.24748053423174 0.00247854246152622 16.4057341442238 59.5729023500552 0.275389203766209 0.783147402240623 -244.838559355501 93.9592024626367 -2.60579648334991 0.0094790407047696 ATP10D other 1 1 1 0.275389203766209 -2.60579648334991 0.975007198134243 11.4268571062849 89.0611309935674 0.128303525666098 0.897968070248854 -10.0588812561335 140.829268451131 -0.0714260704948845 0.943091487807345 OCIAD2 other 1 1 1 0.128303525666098 -0.0714260704948845 0.718942724700096 -20.1332295088964 47.2753689710917 -0.425871441028998 0.670412158596406 -60.5093228655548 74.7548964815751 -0.80943624716902 0.418706783137898 SLC10A4 other 1 1 1 -0.425871441028998 -0.80943624716902 0.0133727003637392 -2557.13561440579 3253.83565896691 -0.785883456455105 0.432360699895809 -12565.6966429717 4763.67729341489 -2.63781441709791 0.00864125197275296 SCD5 other 1 1 1 -0.785883456455105 -2.63781441709791 0.34253244801025 8.53775352119827 20.2523544503209 0.421568442431787 0.673546858929185 -21.1594841989084 28.9091856208136 -0.731929445417317 0.464603070263995 PLAC8 other 1 1 1 0.421568442431787 -0.731929445417317 1.35156015018216e-09 36.7161926177605 119.297690379815 0.307769517589696 0.758404348771194 -823.769908858213 175.960189008752 -4.68156981132385 3.80462730863186e-06 ENOPH1 other 9.56904586328972e-06 0.0328453475554189 1 0.307769517589696 -4.68156981132385 3.94653678986675e-09 21.4615270129496 11.3159290975577 1.8965766600271 0.0585430293806434 -51.053371939366 15.9461444091815 -3.20161229130537 0.00146638067818066 TRMT10A other 2.74126445424145e-05 1 1 1.8965766600271 -3.20161229130537 0.0032464380526099 10.1810591663794 43.7618975755349 0.232646656804735 0.816144464974381 -151.571326724057 64.0682504117348 -2.365779083243 0.0184267679726926 KLHL8 other 1 1 1 0.232646656804735 -2.365779083243 0.724829117251795 -225.778591000875 281.374510022871 -0.80241309343381 0.422750195269921 -217.456750703065 409.097056087525 -0.531552959052683 0.595305740919356 SNCA other 1 1 1 -0.80241309343381 -0.531552959052683 2.38752118447519e-19 119.467888835941 85.9864505835173 1.38938039685571 0.16542299051789 -768.939374050331 125.007240254089 -6.15115870478695 1.73579686217147e-09 PYURF other 2.02724423773788e-15 1.62019279115085e-05 1 1.38938039685571 -6.15115870478695 3.79035944707373e-08 -4.13651858193841 53.1927446867098 -0.0777647140846244 0.938050808234096 -346.003932014206 74.5800791603052 -4.63936128668478 4.62537267975431e-06 TBCK other 0.000250391145073691 0.0397920811639263 1 -0.0777647140846244 -4.63936128668478 0.00107193902710109 198.138459673875 270.004551379155 0.73383377673378 0.463444472790817 -887.820607221415 378.599753740627 -2.34501105309659 0.0194741337344245 CAMK2D other 1 1 1 0.73383377673378 -2.34501105309659 1.40637466261164e-06 80.8042745949484 30.0271183029646 2.69104326894301 0.00739546149175335 -72.3209595058528 43.7203892509346 -1.65417007361861 0.098809376525041 CISD2 other 0.0084213714797185 1 1 2.69104326894301 -1.65417007361861 0.211857572593842 -22.6475666021705 72.5523168691284 -0.312154974223948 0.755071635848878 -152.604279136053 102.239039502776 -1.49262238649952 0.136257636824491 DDIT4L other 1 1 1 -0.312154974223948 -1.49262238649952 6.38769586438854e-05 -339.314562227207 724.876727045894 -0.468099677596249 0.639947218625663 -3761.90939363298 1016.42046013701 -3.70113505303297 0.000242124877136518 ANK2 other 0.324431072952294 1 1 -0.468099677596249 -3.70113505303297 0.0319370480933718 27.8215505913272 16.6563594052814 1.67032602469574 0.0955692698160006 -11.5293410925474 23.4143225121248 -0.492405496105092 0.622679437636629 TIFA other 1 1 1 1.67032602469574 -0.492405496105092 5.49399024387808e-11 71.5079607046067 13.8145147291054 5.1762919007172 3.45850135284304e-07 -7.15719662752177 19.4212493575929 -0.368524006655813 0.712661007842452 SPATA5 other 4.07159616973804e-07 1 0.0031354773264875 5.1762919007172 -0.368524006655813 6.63462795805822e-09 251.418021961437 40.4673148077705 6.21286643691912 1.21598275117851e-09 264.172827440475 56.8965753958957 4.64303564146553 4.55049156968982e-06 CCNA2 essential 4.57125866310212e-05 0.0391615304487506 1.14557734988528e-05 6.21286643691912 4.64303564146553 1.11129436948705e-16 41.1388234828544 27.0521787114891 1.52072126691159 0.12905299617285 -213.966176616078 37.3935860945937 -5.72200205871703 1.95686080677982e-08 METTL14 essential 9.16484466515968e-13 0.00017997248839954 1 1.52072126691159 -5.72200205871703 0.000736011422415564 -44.9802231939677 80.5580086956921 -0.558358180921285 0.57688578340191 -361.45069748115 111.353427977024 -3.24597728195425 0.00126051308941037 USP53 other 1 1 1 -0.558358180921285 -3.24597728195425 3.51815563091645e-07 37.0185548872411 219.087283215821 0.168967154751626 0.865900478874913 -1171.7649924919 296.652161236595 -3.94996276988982 9.10727066321194e-05 SETD7 other 0.00219497729812877 0.727437590280644 1 0.168967154751626 -3.94996276988982 2.14835617530583e-09 19.750929116832 11.6671413011622 1.69286791057074 0.0911916975799295 -48.6744843487772 15.6598117066616 -3.1082419929782 0.00200464634265388 NAF1 essential 1.51050922685753e-05 1 1 1.69286791057074 -3.1082419929782 4.20290715312865e-05 77.1830529089815 106.014744811943 0.728040736653139 0.466977671765739 -367.825568743611 142.294577483126 -2.58495843797863 0.0100613797567178 MARCH1 other 0.21855117196269 1 1 0.728040736653139 -2.58495843797863 0.00110449040357326 -1679.30435952638 851.412900330383 -1.97237363783746 0.0491999046074865 -4031.18161703146 1124.69730624693 -3.58423692725232 0.000376329939875812 SFRP2 other 1 1 1 -1.97237363783746 -3.58423692725232 0.00135012657254517 580.146337796504 312.835190290741 1.85447915005128 0.0643456280394094 -326.39039341639 414.718748842283 -0.787016247342402 0.43169994078869 RPS3A essential 1 1 1 1.85447915005128 -0.787016247342402 0.206624049790369 -3.02155698707429 26.4716361097078 -0.114143189886409 0.909176827788588 -44.8754227892161 34.9647491782791 -1.28344758203196 0.200017035328135 RNF175 other 1 1 1 -0.114143189886409 -1.28344758203196 4.83317072188197e-05 248.396142293061 95.6395090025136 2.59721264656986 0.00971619747477582 -89.4684900445549 130.514242283304 -0.685507485461608 0.493388049081575 PDGFC other 0.248811628762484 1 1 2.59721264656986 -0.685507485461608 9.08309629409926e-15 146.374756801963 67.3807399498675 2.17235306277237 0.0303671461022792 -360.231797520573 91.2816683004683 -3.94637613693488 9.24624096610194e-05 CBR4 other 7.2746518219441e-11 0.738127416323917 1 2.17235306277237 -3.94637613693488 0.295309074553732 -171.038092720741 111.160683012182 -1.53865636739563 0.124613603080876 -139.666346013575 150.590993840688 -0.927454839439664 0.354203549602147 GLRA3 other 1 1 1 -1.53865636739563 -0.927454839439664 1.453853165028e-08 119.461483035242 66.9339176576126 1.78476753215498 0.0749910089121464 -245.746774908066 88.1481542836918 -2.78788338683946 0.00553628873619943 CYP4V2 other 9.85421675255978e-05 1 1 1.78476753215498 -2.78788338683946 0.802451085843323 -7.68783284186438 23.0554189509695 -0.333450147152546 0.738954814292401 -25.1890101668059 38.2505198466384 -0.658527263624096 0.510546971724692 ROPN1L other 1 1 1 -0.333450147152546 -0.658527263624096 0.000246683686334064 167.952293177097 105.338401437006 1.59440708123461 0.111572833369762 -312.955417211825 162.005929094074 -1.93175286214431 0.0540406784274136 NDUFS6 other 1 1 1 1.59440708123461 -1.93175286214431 1.40751967467982e-08 -45.3750825227782 257.201697443153 -0.176418285625067 0.86004725480169 -2129.81545706615 426.715240072645 -4.99118676123112 8.68952714146524e-07 MARCH6 other 9.55002099270257e-05 0.00768067304034113 1 -0.176418285625067 -4.99118676123112 0.0982501516937536 -4.09367355778975 13.1838461273248 -0.310506776114841 0.756323645683852 -37.9233794251538 20.2588657626453 -1.8719399135898 0.0618826317373273 NKD2 other 1 1 1 -0.310506776114841 -1.8719399135898 0.178676050441804 -2.14544920728155 47.1881109687817 -0.0454658845890422 0.963757073525052 -145.076534057546 91.4852380028953 -1.58579173235528 0.113521645085177 CDH18 other 1 1 1 -0.0454658845890422 -1.58579173235528 0.991487445756483 2.11825195270301 37.6519468091208 0.0562587630180621 0.955161500088975 -3.45980576185436 60.8912961757847 -0.0568193810797914 0.954715164202557 ADAMTS16 other 1 1 1 0.0562587630180621 -0.0568193810797914 0.205191339563607 -41.8410725365938 97.2153373843896 -0.430395796201932 0.667120418777264 -255.725838936416 157.603199905821 -1.6225929364964 0.105399261652084 SRD5A1 other 1 1 1 -0.430395796201932 -1.6225929364964 1.00980977707454e-06 -436.193298969083 567.588983555877 -0.768502052729043 0.442605980939822 -4845.96232427368 1022.89659120771 -4.73748995345869 2.93443408856359e-06 MYO10 other 0.00611843743929464 0.025423936943315 1 -0.768502052729043 -4.73748995345869 0.813085834095421 -12.3174005720532 39.1923765843164 -0.314280522018208 0.753458317077018 17.3242715215636 65.8524767355228 0.26307699239835 0.79261551057709 FAM105A other 1 1 1 -0.314280522018208 0.26307699239835 0.0238347761912009 1478.35509891661 928.313053342638 1.59251784039167 0.111996431215238 -2290.43970796043 1974.81888398366 -1.15982266856801 0.246758669965932 RPL37 essential 1 1 1 1.59251784039167 -1.15982266856801 0.0676688731435209 58.3218318695111 41.8193916685112 1.39461215341939 0.163839726041699 -84.5486103189989 89.7554543407593 -0.941988550333749 0.346717756799068 SKP2 other 1 1 1 1.39461215341939 -0.941988550333749 0.831396165840354 16.900552804333 138.02929781277 0.122441779188487 0.902605828554642 171.54403240048 296.279525412457 0.578993881408679 0.562893673530434 OSMR other 1 1 1 0.122441779188487 0.578993881408679 0.497577833535804 30.3667640539974 178.682364674232 0.169948299650954 0.865129263470819 -380.44045939956 378.152269030537 -1.00605097617129 0.314946507824399 MEGF10 other 1 1 1 0.169948299650954 -1.00605097617129 0.000335965953049557 55.6356004380129 52.6689130668873 1.05632710451719 0.291402405098156 -327.999756661394 104.296943539818 -3.14486451404179 0.0017750274326185 YIPF5 other 1 1 1 1.05632710451719 -3.14486451404179 0.019447070226911 -180.278954188582 132.690629018687 -1.35864119057867 0.174962796502929 -737.978458723985 262.765831373569 -2.80850236450575 0.00520085250314867 ARHGAP26 other 1 1 1 -1.35864119057867 -2.80850236450575 0.0335078450868296 233.937790334616 138.789581548325 1.68555728553128 0.0925965882914798 -224.846825167157 254.693528110629 -0.882813265162719 0.377823650185204 RNF145 other 1 1 1 1.68555728553128 -0.882813265162719 0.32428480892832 6.65446943966367 6.35607933022565 1.04694562385637 0.29570469834236 -4.73283122896265 11.6640763053425 -0.40576133978092 0.685117017303538 C1QTNF2 other 1 1 1 1.04694562385637 -0.40576133978092 0.559473451200997 -85.0277107697936 231.850432015705 -0.366735183672351 0.713994880130324 -451.485572078534 425.487614589282 -1.06110156112146 0.289232517827656 GABRB2 other 1 1 1 -0.366735183672351 -1.06110156112146 0.00539972078734486 59.7209514539496 49.368892389769 1.20968789379455 0.227052662869769 -222.776970028795 97.7621196712382 -2.27876575076284 0.0231626420429859 FBXO38 other 1 1 1 1.20968789379455 -2.27876575076284 0.0355473453975948 39.8034088354317 30.1495562948781 1.32019882634869 0.187459714124601 -85.1125927383097 58.0788997179585 -1.46546496492929 0.143513212479972 PCYOX1L other 1 1 1 1.32019882634869 -1.46546496492929 0.0175449141319263 206.681462053995 104.610249345818 1.97572860543283 0.0488141742087876 -189.788659990102 203.740120916407 -0.9315232519567 0.352097296346609 TNIP1 other 1 1 1 1.97572860543283 -0.9315232519567 0.000194748254688584 370.155102040814 163.486774769724 2.26412871966059 0.024054433690712 -624.551020408167 310.476725333786 -2.01158724454056 0.0448754566694272 G3BP1 other 0.929105515666945 1 1 2.26412871966059 -2.01158724454056 0.00250473659517496 241.199476356419 69.4673759968961 3.47212591371231 0.000567766632302844 232.493250711936 133.81917547088 1.73736872831449 0.0830266482142933 ZNF300 other 1 1 1 3.47212591371231 1.73736872831449 0.141737080601697 -9.68625437854828 16.849380991595 -0.574873010669063 0.565672344719435 -62.7866374475867 32.3131358871279 -1.94306852999056 0.0526482215311117 N4BP3 other 1 1 1 -0.574873010669063 -1.94306852999056 0.00198127555235176 203.655091194588 106.032902083719 1.92067827242709 0.0554211832574291 -352.044812175385 203.346079909219 -1.73125939940692 0.084109685769436 NHP2 essential 1 1 1 1.92067827242709 -1.73125939940692 2.41271565509574e-07 186.883923179127 104.933553429136 1.78097393133012 0.075609646611429 -776.672846962194 201.237788662164 -3.85947814337229 0.000130730749754804 RMND5B other 0.00152073467740684 1 1 1.78097393133012 -3.85947814337229 0.000324136429759063 210.189951475945 56.1581756938444 3.74282014825108 0.000206265654271481 50.9186615446852 105.246979707856 0.48380164149152 0.628768990215757 BOD1 other 1 1 1 3.74282014825108 0.48380164149152 0.0385344787725242 -952.237071523989 1244.9614078361 -0.764872762746194 0.444759215967827 -6184.40955631403 2448.86120300332 -2.52542265308028 0.0119077252576576 CPLX2 other 1 1 1 -0.764872762746194 -2.52542265308028 0.169406541464333 79.7358728576067 81.1394058945083 0.982702202198443 0.326300267293943 -123.087856058375 143.318070206187 -0.858843939785769 0.390899625832632 TENM2 other 1 1 1 0.982702202198443 -0.858843939785769 0.0765817070427701 -63.3536256606295 41.9802799660989 -1.50912823144082 0.131990316447754 -171.687253453554 77.0382437669849 -2.22859770756004 0.0263497975493825 KCNMB1 other 1 1 1 -1.50912823144082 -2.22859770756004 0.0207935779225747 -35.4304114897981 28.8058893426449 -1.22997110307391 0.219371175862805 75.4787459776063 49.7034391030274 1.5185819601165 0.129592519363341 FAM50B other 1 1 1 -1.22997110307391 1.5185819601165 0.349319300009765 3.18521005136987 5.26362903746004 0.605135739753213 0.545405814203025 -7.44561544543442 9.08386099015109 -0.819653168791014 0.412864788320966 MYLK4 other 1 1 1 0.605135739753213 -0.819653168791014 5.33652807432909e-08 78.1810640019248 15.2901668705597 5.11315963153139 4.74868924109463e-07 2.8909234032316 26.3809810325151 0.109583620096178 0.912789904837399 FARS2 other 0.000349329127745582 1 0.00429186533610133 5.11315963153139 0.109583620096178 0.117711052320361 -137.323117040072 115.777561377756 -1.18609439865483 0.236233950854991 -424.159368731071 205.034544057767 -2.06872149607905 0.0391638386798814 GFOD1 other 1 1 1 -1.18609439865483 -2.06872149607905 1.92995241730518e-09 120.833681164548 25.0024072079878 4.83288189650572 1.8662447499171e-06 -66.7137548596624 46.4756142831381 -1.43545719381415 0.151872209128188 CDKAL1 other 1.35907249226631e-05 1 0.0166207757427617 4.83288189650572 -1.43545719381415 0.00231302726389213 2.12624321880681 9.72418600539303 0.218655136545886 0.827020776628625 68.4217080387972 20.5016873373256 3.33736959856118 0.000918071089698599 PCDHB18P other 1 1 1 0.218655136545886 3.33736959856118 0.0153015462817598 60.2169519875703 116.078467231203 0.518760743692721 0.604191997109341 -636.086449674861 253.53226817718 -2.50889740484763 0.012474361778478 ZMAT2 essential 1 1 1 0.518760743692721 -2.50889740484763 0.348518941567927 -9.28552844801566 23.4111729335444 -0.396628074739092 0.691834916178599 48.944579175002 46.1740357059258 1.06000219445234 0.289727774406625 DCDC2 other 1 1 1 -0.396628074739092 1.06000219445234 0.305108241099424 -11.0696448054309 10.629342861105 -1.04142325166094 0.298257607480282 -31.7878328686305 21.5046980536119 -1.47818085096486 0.140083062924641 TRIM7 other 1 1 1 -1.04142325166094 -1.47818085096486 5.84484314237285e-11 -78.1179536913564 73.1963674362719 -1.06723812160992 0.28645625528371 -998.615569563993 148.086838566295 -6.7434457999921 4.93811791877861e-11 TRIM41 other 4.32576840967014e-07 4.68528628133714e-07 1 -1.06723812160992 -6.7434457999921 0.00106865062604027 109.367673245289 102.284778498491 1.06924681121446 0.28554737454884 -542.616894197952 201.195976153278 -2.69695698975892 0.00726754489704562 HIGD2A other 1 1 1 1.06924681121446 -2.69695698975892 0.0179323525859201 118.539557917624 103.786023092489 1.14215338814926 0.254014250526349 -350.994685348471 199.037096320934 -1.7634636549486 0.0785195046840518 FAM193B other 1 1 1 1.14215338814926 -1.7634636549486 0.348233388723207 -31.8788588491882 22.3810651393508 -1.4243673681615 0.155053845641756 -42.4441537245487 51.7839417767983 -0.819639298751988 0.4128685634787 PLA2G7 other 1 1 1 -1.4243673681615 -0.819639298751988 0.000579800533597458 -429.810644257708 435.896270625716 -0.986038819833737 0.324658434601872 -3918.7829418947 1016.00206285386 -3.85706199344438 0.000131986114487218 TNFRSF21 other 1 1 1 -0.986038819833737 -3.85706199344438 3.66071234094165e-06 81.4078869268448 81.0602541911608 1.00428857199071 0.315794031371089 -634.210750853243 159.446959837373 -3.97756565255371 8.14509066249469e-05 RNF44 other 0.0212284708651206 0.652503212972449 1 1.00428857199071 -3.97756565255371 0.000781541554682787 75.4390504802224 65.3837718865954 1.1537885977436 0.249216035589234 -430.539191588147 148.837050827328 -2.89268827348395 0.00401000545736074 MUT other 1 1 1 1.1537885977436 -2.89268827348395 0.269255069595769 43.1638380409751 59.1298682801494 0.729983666401397 0.465793087479005 -118.063522851255 119.628276171935 -0.986919870696524 0.32423054122924 RASGEF1C other 1 1 1 0.729983666401397 -0.986919870696524 0.5616269737744 -22.2964730039856 38.9571120578657 -0.572333826256605 0.56738947848849 39.7928838886686 74.7105461217733 0.532627399401 0.59456163422163 DOK3 other 1 1 1 -0.572333826256605 0.532627399401 1.94520673410806e-16 137.06848653219 19.0861028311241 7.18158587664475 3.00667701958639e-12 -75.3197246044209 40.6006670427729 -1.85513515147599 0.0642532578697086 ABT1 essential 1.59779281139636e-12 1 2.8888152804186e-08 7.18158587664475 -1.85513515147599 0.0356796259435354 252.774455549711 144.206194708047 1.75286821805031 0.0803242316935923 -343.227774855338 316.795402528625 -1.08343672956025 0.279210668150465 PPP1R18 other 1 1 1 1.75286821805031 -1.08343672956025 0.0170038361507045 -4062.85252275089 1734.7128677334 -2.34208934419186 0.0196242623085866 -9813.25365741276 4043.41505794374 -2.42697163580413 0.0156287852570625 DAAM2 other 1 1 1 -2.34208934419186 -2.42697163580413 0.000193962507133831 40.9677543686962 14.8418554146323 2.76028523551758 0.00601974270364984 -38.8941373196629 28.7704191803977 -1.35187941043844 0.17711799693937 PRIM2 other 0.925783046549774 1 1 2.76028523551758 -1.35187941043844 5.5510610668971e-06 137.866099201852 29.7336141048378 4.63670843092769 4.68811732468951e-06 22.0214366665863 67.2313510671114 0.327547138605086 0.74341167253781 MLIP other 0.0316577012645142 1 0.0412226156359949 4.63670843092769 0.327547138605086 0.0463458693401871 -49.0004099250075 26.4560636758426 -1.85214287829789 0.0646825983647029 -137.262134985893 59.8204072526465 -2.29457038642645 0.0222332438956386 HMGCLL1 other 1 1 1 -1.85214287829789 -2.29457038642645 0.461062742870453 -9.83594843306074 49.5268492310316 -0.198598307499398 0.84266912632204 123.323607989483 116.277856910741 1.06059409130795 0.289458887026161 FGD2 other 1 1 1 -0.198598307499398 1.06059409130795 0.11017840064334 8.9541580085663 13.5708129291833 0.659809994824321 0.50972255906578 66.9087966300556 31.8612039417462 2.10000842254389 0.036299484451163 SCUBE3 other 1 1 1 0.659809994824321 2.10000842254389 0.0212354019119499 -0.652316244595355 5.72681504963794 -0.113905589571396 0.909364826905263 -16.8749199842776 8.38438254997867 -2.01266102586416 0.0447618257082771 ANO7 other 1 1 1 -0.113905589571396 -2.01266102586416 0.0123924708148969 0.23753378003198 9.7881112865029 0.0242675806475068 0.980650224280095 -67.4893199570577 24.3670075377282 -2.76970078712217 0.00584922674373652 CRIP3 other 1 1 1 0.0242675806475068 -2.76970078712217 3.12766063817093e-05 -2.57563025210025 52.2059746476592 -0.0493359288756376 0.960674076362761 -561.133053221286 129.964131027821 -4.31759939287529 1.95245834461661e-05 TTBK1 other 0.165203034908189 0.162737403023794 1 -0.0493359288756376 -4.31759939287529 0.019174777084848 -153.435556410933 92.1152861293358 -1.66569049349203 0.0964933588175145 -517.648285083367 186.161988067142 -2.7806336323432 0.00566028294757248 TCTE1 other 1 1 1 -1.66569049349203 -2.7806336323432 1.43726729742206e-14 594.722966719736 124.048567471881 4.79427516851047 2.2406096921874e-06 -1413.19992842952 308.812628928707 -4.57623748527386 6.17407383722614e-06 RPL7L1 essential 1.14737048353203e-10 0.0527821572344463 0.019894373456932 4.79427516851047 -4.57623748527386 0.554817663429311 31.2440286866152 34.4619551412399 0.906623798869326 0.365106545686449 -9.81119709892367 69.6464870419672 -0.140871385128322 0.88803660812484 NFKBIE other 1 1 1 0.906623798869326 -0.140871385128322 0.317074000179254 -2.76267986006409 5.7434251464132 -0.481016081804322 0.630745812710781 15.1867068226064 13.2887863705082 1.14282120271798 0.253738546613438 CYP39A1 other 1 1 1 -0.481016081804322 1.14282120271798 0.374026566278803 4.66216253254768 33.9034501319639 0.137512923150916 0.89068871382846 49.7019048924215 46.7717699786566 1.06264750970729 0.288528705271341 TPBG other 1 1 1 0.137512923150916 1.06264750970729 6.45504155528676e-05 23.6631646017709 20.6716457119862 1.14471604880738 0.252953369967256 -62.1167646017688 28.722172644365 -2.16267638840878 0.0311078421376552 IRAK1BP1 other 0.327464258099697 1 1 1.14471604880738 -2.16267638840878 3.02701158106277e-05 167.424424778764 102.156275605823 1.63890494035611 0.101952755468661 -258.984424778758 141.940812334766 -1.82459449483737 0.0687448650136248 PHIP other 0.160159182754031 1 1 1.63890494035611 -1.82459449483737 0.000243497117957292 57.3656297108329 94.4757777488629 0.607199338049624 0.544033989631624 -308.56639714952 130.334798618577 -2.36749049693578 0.0183438635542875 PRSS35 other 1 1 1 0.607199338049624 -2.36749049693578 5.4694152215698e-06 109.621440830876 27.7691063756187 3.94760419539908 9.20375838179933e-05 32.8822244296216 37.5856011120327 0.874862273230869 0.382131621380399 MMS22L other 0.0312303609151636 1 0.766212885284794 3.94760419539908 0.874862273230869 4.57980367000702e-06 -20.5500798003297 90.5478857652703 -0.226952618790042 0.820566957390688 -433.924661593313 122.54763476542 -3.54086525149121 0.000441764998461513 FAXC other 0.0263595621638359 1 1 -0.226952618790042 -3.54086525149121 0.000653411147404573 302.175647616613 116.914568381423 2.58458506754089 0.0100721129219004 -28.4918499683559 165.218538184152 -0.172449473778778 0.863163834759965 PNRC1 other 1 1 1 2.58458506754089 -0.172449473778778 3.23353325179224e-11 237.555606755421 69.3343631312343 3.4262319004183 0.000669768366486459 -192.071318328688 97.9802797979783 -1.96030587710825 0.050593555067908 PM20D2 other 2.40930562591039e-07 1 1 3.4262319004183 -1.96030587710825 4.14576526072405e-18 102.08839009116 29.9790075171019 3.40532921354794 0.000721749518200307 -156.79677107738 42.3650180363176 -3.70109062488692 0.000242035398650626 RARS2 essential 3.47249298238247e-14 1 1 3.40532921354794 -3.70109062488692 3.55988644029109e-14 41.3547342284164 23.5770733177891 1.75402322718375 0.0801290788995885 -110.643033070014 30.5625899636824 -3.62021128449818 0.000328924939439971 TBC1D32 other 2.8261938449471e-10 1 1 1.75402322718375 -3.62021128449818 0.00187406138386995 -264.322670431219 175.342135720179 -1.50746806719088 0.132414930542827 -727.622142792776 227.293257527805 -3.20124824953844 0.00146842542154427 CLVS2 other 1 1 1 -1.50746806719088 -3.20124824953844 9.5765047700966e-10 27.0275678987131 24.7700853118894 1.09113745707368 0.275813638814786 -105.0221564223 32.2338431802252 -3.25813325563143 0.00120897331627111 RNF217 other 6.82325964869383e-06 1 1 1.09113745707368 -3.25813325563143 0.183321236992975 11.8660115666104 21.0706076360079 0.563154692621791 0.573617713557792 -17.7269782778765 27.2049591412136 -0.651608340444864 0.514995613482713 RSPO3 other 1 1 1 0.563154692621791 -0.651608340444864 0.133923589085109 106.869843282693 68.9162120687561 1.55072137708426 0.121692347913876 178.150630458192 88.6639874017272 2.00927835166052 0.0451220223388275 ARHGAP18 other 1 1 1 1.55072137708426 2.00927835166052 0.0813368799464826 41.8281040446113 22.1263631976988 1.89041930076252 0.0593617651928042 62.9323604150496 28.0902797518612 2.24036075720748 0.0255681756681235 ABRACL other 1 1 1 1.89041930076252 2.24036075720748 0.0218211496807336 76.7679676541019 180.491964650226 0.425326234344394 0.670807760595735 -307.902756002967 230.600876224015 -1.3352193670932 0.182498073280389 SLC18B1 other 1 1 1 0.425326234344394 -1.3352193670932 0.0105809139399208 15.0490694386059 6.11089857912958 2.46266064535954 0.0141748932786303 6.92437039018616 7.78220994543149 0.889769157956356 0.374078283959022 MTFR2 other 1 1 1 2.46266064535954 0.889769157956356 0.865570700313406 1.65731495997966 34.8709658211558 0.0475270736256519 0.962114815745791 -12.8512253486268 44.5519848416484 -0.288454608572525 0.773135228043273 SLC2A12 other 1 1 1 0.0475270736256519 -0.288454608572525 4.83893684099971e-11 -12.737396083075 57.437795816043 -0.221759834306129 0.824604677165863 -326.490415577314 73.1608269768876 -4.46263976322269 1.03187959591436e-05 SHPRH other 3.59339449812638e-07 0.0873692453860687 1 -0.221759834306129 -4.46263976322269 2.74090163194658e-21 -80.2349005904889 76.3572206310259 -1.05078340892213 0.293938800607239 -677.823783090428 96.9478284341042 -6.99163451145425 1.02265353230468e-11 AIG1 other 2.37142809196018e-17 9.75918265878359e-08 1 -1.05078340892213 -6.99163451145425 1.91336535008787e-14 195.478039237784 127.072788416707 1.53831549361109 0.124693569109145 -654.233132397874 166.919748441555 -3.91944715053861 0.000102960452920865 DYNLT1 other 1.52476084748502e-10 0.818329679815034 1 1.53831549361109 -3.91944715053861 3.23821419284747e-05 75.9008390334119 92.9964072553826 0.816169584110667 0.414846794546708 -271.868991120116 122.157836453017 -2.22555506068315 0.0265523609605482 TIAM2 other 0.17068627010499 1 1 0.816169584110667 -2.22555506068315 5.64666507718885e-15 -118.415796518364 158.589201567256 -0.746682594704564 0.455655782184743 -1222.6693345818 208.318948226315 -5.86921806677669 8.65274850891820e-09 TMEM181 other 4.53653072301352e-11 7.9960048970913e-05 1 -0.746682594704564 -5.86921806677669 7.90700933870344e-12 434.340044564546 142.299677464518 3.0522911386981 0.00240922705965809 -348.29468547417 186.921422451204 -1.86332139412802 0.0630861051089454 WTAP essential 5.96900134978723e-08 1 1 3.0522911386981 -1.86332139412802 2.7611035364226e-38 135.145888824094 91.4043466353528 1.47854991364079 0.139979411922396 -763.761651965447 117.37208683396 -6.50718303275888 2.09719897707819e-10 ZMYM4 other 2.56727406816573e-34 1.97891695477098e-06 1 1.47854991364079 -6.50718303275888 0.273009582027523 -17.587992013691 18.8349359410203 -0.933796221487878 0.350923506651073 -38.6648443937377 24.8294372635701 -1.55721790966511 0.120140989821991 VIP other 1 1 1 -0.933796221487878 -1.55721790966511 2.12603979177391e-10 26.8681545921281 21.6175823930254 1.24288433848166 0.21457538963328 -94.5302021930651 28.4977027529302 -3.31711657647019 0.000985319353560348 ARMT1 other 1.54796957239059e-06 1 1 1.24288433848166 -3.31711657647019 0.251271652146893 32.1291458721454 28.608826816993 1.12305010190286 0.2620314121062 3.5817071678196 37.579864540634 0.0953092091097563 0.924112816497064 SLC22A3 other 1 1 1 1.12305010190286 0.0953092091097563 4.71938351256119e-19 1577.62375235504 168.526132063512 9.36130042882896 4.15263906500933e-19 -108.96163337718 627.550130231462 -0.173630166146235 0.862236338228707 GNA12 other 3.99778977349058e-15 1 4.05754363042061e-15 9.36130042882896 -0.173630166146235 1.50669313155378e-23 886.213154499953 82.3946255979416 10.7557155344619 4.33312155519379e-24 203.868642639789 311.009461398881 0.655506239980012 0.512487591212893 C7orf50 other 1.32302723881737e-19 1 4.24992562133407e-20 10.7557155344619 0.655506239980012 0.00056001431605639 84.6333695985935 22.5494282944914 3.75323793105959 0.000198077491134162 158.323204332624 83.9685601846014 1.88550576530736 0.0600231582381696 SDK1 other 1 1 1 3.75323793105959 1.88550576530736 3.2344517342572e-25 214.76794342133 19.2998836727807 11.1279397877525 1.72890504600065e-25 -6.98960857082836 76.9189741212512 -0.0908697580886908 0.927637811961341 RBAK other 2.86572423655188e-21 1 1.69692030264964e-21 11.1279397877525 -0.0908697580886908 7.06615200356476e-41 239.588262905592 17.7208420107907 13.5201398872413 5.86634348615903e-35 -67.0527558172345 47.9348001348065 -1.39883248972902 0.1625840736499 ZNF7 other 6.61179842973554e-37 1 5.77130872168326e-31 13.5201398872413 -1.39883248972902 5.19557408820528e-21 405.54408216522 40.6205728545555 9.98371154481979 2.90922532636097e-21 190.866841124403 110.203199884765 1.73195371208807 0.0839939709565025 ARHGAP39 other 4.4848195529388e-17 1 2.84754974944212e-17 9.98371154481979 1.73195371208807 0.700014399695538 -1.76788319673183 6.67251097459553 -0.264950211916136 0.791173605762688 12.087233857385 18.5120984284421 0.652936991671027 0.514142619596538 SLC39A4 other 1 1 1 -0.264950211916136 0.652936991671027 7.21366255380891e-06 235.849226008904 47.8142073249736 4.93261813180198 1.15421382549252e-06 233.009738256202 140.273917354967 1.66110523360208 0.0974078965424698 NAPRT other 0.040620133840498 1 0.0103290595243326 4.93261813180198 1.66110523360208 0.000972399587666123 151.937242251593 51.1796792380102 2.96870251071741 0.00315624154387555 20.0766298054058 58.9439850060075 0.340605233992231 0.733565597840373 VLDLR other 1 1 1 2.96870251071741 0.340605233992231 4.12421689136722e-15 301.085548903142 96.8610758851881 3.10842664250422 0.00200399358953453 -403.390215706608 111.524763108374 -3.61704615605965 0.000332852225218941 AK3 other 3.32494365782026e-11 1 1 3.10842664250422 -3.61704615605965 5.12194636387111e-13 231.358701856927 39.9048096533647 5.79776482751419 1.29128729531305e-08 9.38301815990277 45.9613629073371 0.204150128855402 0.838331439119811 UHRF2 other 3.9700206266365e-09 1 0.00011990893824277 5.79776482751419 0.204150128855402 7.34632949338326e-16 1585.36172390493 346.22715440243 4.57896413885034 6.10138606660298e-06 -799.800251735805 391.083067780799 -2.04509046191714 0.0414443872258437 NFIB other 5.98432000531001e-12 1 0.0533871280827761 4.57896413885034 -2.04509046191714 0.501383249821757 28.3788862645212 45.6998936151454 0.620983639557448 0.534934882513497 -14.3088168874344 51.5236179854794 -0.277713744626144 0.781363745566268 PLIN2 other 1 1 1 0.620983639557448 -0.277713744626144 4.29508069383775e-21 198.53712451595 36.0108977193648 5.51325118477086 6.04251739570479e-08 -92.8727704188545 40.5999137116551 -2.28751152227679 0.0226441143897348 HAUS6 other 3.71223824368397e-17 1 0.000555186498317356 5.51325118477086 -2.28751152227679 0.0267095264118904 248.886090757673 102.569493617099 2.4265118407115 0.0156814624044584 82.5095905040119 121.130592691738 0.681162278417874 0.496159054353277 CDKN2B other 1 1 1 2.4265118407115 0.681162278417874 5.97290054313767e-07 372.264395601339 78.3344083692176 4.75224621403567 2.80118002584912e-06 100.149951236688 92.5098972345729 1.08258634189965 0.279637790564728 CDKN2A ts 0.00368050131468143 1 0.0248296597491266 4.75224621403567 1.08258634189965 8.99474455274001e-06 124.609480911108 42.7411902958716 2.91544245839929 0.00374065119524161 -44.9955399194598 48.5537670397457 -0.92671573521014 0.354602578280386 C9orf72 other 0.0502806220498166 1 1 2.91544245839929 -0.92671573521014 4.96597096316026e-06 103.190232381986 22.2264182115786 4.64268382785269 4.56650679857928e-06 20.598330022438 26.1811783948798 0.786760997223345 0.431852176070701 ZCCHC7 other 0.0284748775027609 1 0.0401806933206991 4.64268382785269 0.786760997223345 1.28713070360819e-06 166.210474580948 36.8637120270705 4.50878290441541 8.4000634948634e-06 -3.3579951205874 43.4361170717798 -0.0773088237845521 0.938413498903 FBXO10 other 0.00772921987516717 1 0.0731897532307448 4.50878290441541 -0.0773088237845521 5.62155001276602e-06 314.52003585289 70.1676879343385 4.48240557886432 9.46153430726718e-06 63.9596858335716 81.8102870239626 0.781804931387632 0.434756503145221 SIGMAR1 other 0.032025970422728 1 0.082230194664459 4.48240557886432 0.781804931387632 3.61542490617164e-10 309.478092606506 66.3837697341473 4.66195417714147 4.16957841349188e-06 -337.764263572782 138.480662299184 -2.43907169394562 0.0151229722131474 CEP78 other 2.61539837712457e-06 1 0.036738155401277 4.66195417714147 -2.43907169394562 5.80061168512755e-05 -1496.34961049486 5045.86236386748 -0.296549826885876 0.766950786734572 -45402.5841174026 10842.3998843644 -4.18750319132543 3.41123076396815e-05 NTRK2 other 0.296295244876315 0.280880741105137 1 -0.296549826885876 -4.18750319132543 1.14233349716706e-05 30.2370923683941 19.0236633776808 1.58944635258156 0.112681175690026 -143.626614507807 40.877485498487 -3.51358731478538 0.00048808107063768 IDNK other 0.0631025023835084 1 1 1.58944635258156 -3.51358731478538 0.851441990890845 233.647371260926 745.747423365953 0.313306307122526 0.754197097925091 896.880832743185 1602.44001793792 0.559696976300757 0.575972248869919 SHC3 other 1 1 1 0.313306307122526 0.559696976300757 0.155369458489901 17.6355124835741 14.2065863136141 1.2413617243626 0.215138056878766 -25.8492444152432 29.3875825876194 -0.879597508171127 0.37956081500758 AUH other 1 1 1 1.2413617243626 -0.879597508171127 0.000410138191699643 83.3644614124547 61.9609757238833 1.34543493607899 0.179182514122835 -402.86286031335 135.118278314568 -2.98155708715772 0.00302815747110717 MFSD14B other 1 1 1 1.34543493607899 -2.98155708715772 0.0154614513263531 914.66124052764 323.344398706898 2.8287523896672 0.00488752755993875 318.15787257929 709.681247916891 0.448310947362877 0.65415048391333 PLPPR1 other 1 1 1 2.8287523896672 0.448310947362877 0.245383703789464 188.545627259375 113.224927229661 1.66523072147299 0.0965817963665845 106.312816092459 235.909184608306 0.450651449916954 0.652463774732311 ZNF462 other 1 1 1 1.66523072147299 0.450651449916954 1.01227334250423e-08 140.801220363681 31.0113460034507 4.54031309534303 7.27302841487899e-06 -133.545368993047 63.6788415696943 -2.09717020129656 0.0365525702584045 INIP other 6.90977783593387e-05 1 0.0635153571471382 4.54031309534303 -2.09717020129656 0.401590557342442 56.8694766194769 63.2149859062539 0.899620173985529 0.368816738785983 -75.5322822822823 130.762963907563 -0.577627487364669 0.563812455467474 UGCG other 1 1 1 0.899620173985529 -0.577627487364669 0.0573011937829368 36.151082744472 85.0988005476624 0.424813070358429 0.671182031338172 -338.333188967405 170.895500720408 -1.97976650959894 0.048356744955672 SNX30 other 1 1 1 0.424813070358429 -1.97976650959894 0.0318169592634397 -1226.45012930289 545.567856876483 -2.24802490440811 0.0250712667310776 -2409.13444756153 1118.49792003801 -2.15390158926684 0.0317928180086271 STOM other 1 1 1 -2.24802490440811 -2.15390158926684 0.39045800950578 848.801826993061 1095.63898536549 0.774709405498119 0.438929397874813 -1650.2436203989 2246.22823870158 -0.734673169879126 0.462931706280598 GSN other 1 1 1 0.774709405498119 -0.734673169879126 2.74613223784774e-06 89.6955214606205 25.1239263235933 3.57012356688809 0.000396301174872114 -101.922926965966 51.5079086532209 -1.9787820866921 0.0484664960652391 MRRF other 0.0160840965170742 1 1 3.57012356688809 -1.9787820866921 0.00128479147241158 36.8664330535405 11.6192297310777 3.17288098323203 0.00161559732619668 -14.8356287181159 25.6815098580643 -0.577677434080356 0.563778757544958 NR6A1 other 1 1 1 3.17288098323203 -0.577677434080356 0.762365027548838 73.3274602884791 210.727139417606 0.347973500191465 0.728027255974357 -208.248989279845 442.602690822225 -0.470509993721412 0.638224905002455 CRB2 other 1 1 1 0.347973500191465 -0.470509993721412 0.000193249906069865 -312.947344815216 158.326279922949 -1.97659759938473 0.0487154246238586 -1334.04969501257 320.272624641613 -4.16535661299613 3.74738686172653e-05 ALAD other 0.922575051577536 0.3077728829536 1 -1.97659759938473 -4.16535661299613 0.245756794029736 -125.998310016451 316.521060056968 -0.398072437877511 0.690771188221645 -1092.48882553491 659.499055579226 -1.65654342685207 0.0983295930413171 ASTN2 other 1 1 1 -0.398072437877511 -1.65654342685207 1.1800864118618e-05 11.2587011123067 12.7593646149255 0.882387285894837 0.37805251743287 -102.517581628993 25.8104668155547 -3.97193829780756 8.33597365571784e-05 WDR31 other 0.0651171682065339 0.66737805087677 1 0.882387285894837 -3.97193829780756 2.38299569452191e-08 323.717617509868 67.2837835645977 4.81122791198377 2.06889004740349e-06 -187.728381772516 136.105982964666 -1.37928089334068 0.168513606894849 POLE3 other 0.000159446241920461 1 0.0183934475129255 4.81122791198377 -1.37928089334068 2.8082329556398e-07 738.961594363327 164.476727866062 4.49280335249058 9.00556560604417e-06 -395.502844327224 339.365124222182 -1.16541982690092 0.244483364262796 SURF4 other 0.00176469358932405 1 0.0783844430350085 4.49280335249058 -1.16541982690092 0.858474576815082 8.0682876516483 15.5706254854082 0.518173637867624 0.604598770782649 12.5457038111187 32.8104304379014 0.382369375947789 0.702372867928514 GBGT1 other 1 1 1 0.518173637867624 0.382369375947789 2.03050756501669e-05 250.551924613298 75.1245291978902 3.33515467302701 0.000925060261441481 -254.492958966609 155.004574289294 -1.64184160456861 0.101340593718811 SURF1 other 0.109403747603099 1 1 3.33515467302701 -1.64184160456861 1.02680108647154e-06 157.623764329923 32.7183860275798 4.81758984679302 2.0058195430802e-06 -6.21113474699393 67.5079039001846 -0.0920060376363862 0.926735307511264 SURF2 other 0.00621830737967162 1 0.0178417648356984 4.81758984679302 -0.0920060376363862 1.74251822279845e-12 334.166448489283 60.437647971572 5.52911073982337 5.54044200656227e-08 -305.088236709627 124.701106215289 -2.44655597668003 0.0148150453086087 SURF6 essential 1.33476895866361e-08 1 0.000509277429243204 5.52911073982337 -2.44655597668003 4.3390482866047e-17 391.087096091097 50.7838477092513 7.70101348622019 9.07874929214639e-14 -122.474564687989 104.78240301792 -1.16884668761647 0.243101149718276 MED22 essential 3.59620321993798e-13 1 8.77461119085949e-10 7.70101348622019 -1.16884668761647 2.05985032296955e-11 231.11077475431 39.0703929637649 5.91524060094942 6.68439543827218e-09 -105.927698260676 80.6140110736808 -1.31401101185573 0.189530263171702 REXO4 other 1.54138599667812e-07 1 6.2378778229956e-05 5.91524060094942 -1.31401101185573 2.40928098859588e-09 3681.4712102107 639.693491791996 5.75505497155781 1.62991524645252e-08 -341.187470521987 1319.8807157867 -0.25849871616514 0.796143466647152 RPL7A essential 1.69059246969773e-05 1 0.0001512072374134 5.75505497155781 -0.25849871616514 8.20792154437305e-11 573.363659572736 88.7284374627935 6.4620055978464 2.75649020804446e-10 19.807171888404 186.96861137434 0.105938487443473 0.915679657599312 GTF3C5 essential 6.05662530759287e-07 1 2.61315271722615e-06 6.4620055978464 0.105938487443473 3.98003527658696e-17 411.957998440902 46.4149592623662 8.87554368220512 1.8060561660611e-17 161.475148517513 100.715030227424 1.6032874949537 0.109593681427922 ASB6 other 3.29905124076293e-13 1 1.75945991697672e-13 8.87554368220512 1.6032874949537 2.64585477086198e-06 336.783025018333 68.9670964750834 4.88324204194977 1.46515163758157e-06 41.234373726671 152.435162140705 0.270504345241616 0.786899692014352 PTGES2 other 0.0155391050692724 1 0.0130779435170531 4.88324204194977 0.270504345241616 1.45142540815699e-17 322.304037525874 36.3303738199306 8.87147594801405 1.86284969953148e-17 85.1912529233093 78.8326598923614 1.0806593744221 0.280444681775266 NTMT1 other 1.20874707991314e-13 1 1.81441560734366e-13 8.87147594801405 1.0806593744221 1.51109403134994e-09 668.88521717871 115.135958324567 5.80952490353301 1.20640525615288e-08 -166.52897074403 254.480315577321 -0.654388416511656 0.513205051155915 CIZ1 other 1.06789015195501e-05 1 0.000112062984244041 5.80952490353301 -0.654388416511656 0.000938841024870521 390.036916306737 112.635664263122 3.46281898241035 0.000587098721891923 -28.7302990791293 248.954017528896 -0.115404038722913 0.908177765693849 SLC25A25 other 1 1 1 3.46281898241035 -0.115404038722913 0.0461491570420338 270.74981597099 160.432336223205 1.68762621267513 0.0921965373026677 -362.147798467785 345.879615450307 -1.04703423471863 0.295662549411395 SH3GLB2 other 1 1 1 1.68762621267513 -1.04703423471863 3.05391690976779e-09 213.53369775621 37.3452063080526 5.71783419791061 2.0020265738516e-08 -39.1475694539099 80.5133547314966 -0.486224547274957 0.62705169989793 MIGA2 other 2.1331609614728e-05 1 0.000185367640472919 5.71783419791061 -0.486224547274957 0.802661024186236 3.65350393806625 16.9213221571753 0.215911257059604 0.829157664108883 24.3101852100752 36.7172889868224 0.662090962619816 0.508261918488187 PTGES other 1 1 1 0.215911257059604 0.662090962619816 8.13927956304479e-20 449.8154184663 48.8877790344173 9.20097879982699 1.46028601750305e-18 2.65149539564796 108.054665263496 0.0245384629084009 0.980434279289943 LRSAM1 other 6.93466618771416e-16 1 1.42538518168473e-14 9.20097879982699 0.0245384629084009 0.0570503530224094 113.717144700411 51.0328165151723 2.22831410189956 0.0263676699209368 2.22544017633897 110.735240094965 0.020096946323776 0.983975208720087 HMCN2 other 1 1 1 2.22831410189956 0.020096946323776 5.23401681264121e-06 317.97543662974 134.316540849456 2.3673587379393 0.0183513122339892 -925.03992659284 291.454221996087 -3.17387725680384 0.00161068373509086 GPR107 other 0.0299333421514951 1 1 2.3673587379393 -3.17387725680384 2.92324629297342e-42 43.8458917331098 3.68687809811079 11.89241698975 2.19804287268241e-28 -18.1327719494568 7.89701445997467 -2.29615534343532 0.022148306273777 IDI2 other 2.74551291836063e-38 1 2.16023653527227e-24 11.89241698975 -2.29615534343532 6.7983465774191e-08 161.68705978706 33.5733066036641 4.81594088112291 2.02305497767859e-06 -80.3653460278465 70.7469165884314 -1.13595545789465 0.256597792442261 INPP5E other 0.000442232444861113 1 0.0179930509714734 4.81594088112291 -1.13595545789465 4.6624986382503e-07 548.247338247341 116.722354773217 4.69702088612369 3.54077111643263e-06 -181.325348075347 245.961674095124 -0.737209765474357 0.461390416636201 SEC16A essential 0.00288935040612371 1 0.0312685685793241 4.69702088612369 -0.737209765474357 1.26496390393596e-09 280.221793856543 46.402321066217 6.03896071182864 3.35793501541625e-09 6.68685658316982 97.7927872014808 0.0683778095964583 0.945516669985145 DPH7 other 8.97491889842562e-06 1 3.14907145745736e-05 6.03896071182864 0.0683778095964583 0.00209760387915897 1538.40447010929 535.085799437029 2.87506129246538 0.00423682222880733 -827.096493186811 1120.24877387068 -0.738315017591167 0.460719351916305 NOTCH1 og 1 1 1 2.87506129246538 -0.738315017591167 0.254771011569519 13.2108635852125 70.4504745958346 0.18751986641682 0.851341499738023 -212.927702871671 148.474216635893 -1.43410558207449 0.152268927582782 CACNA1B other 1 1 1 0.18751986641682 -1.43410558207449 0.00184448001645821 -476.641061304634 378.715676888931 -1.2585723021031 0.208855281757575 -2786.50480792368 781.404727585287 -3.56601989923275 0.000402375956718872 NACC2 other 1 1 1 -1.2585723021031 -3.56601989923275 0.467660667223498 0.396749826424225 2.7581066860991 0.143848614857377 0.885686475064961 6.23170476632959 5.68335964742085 1.09648256540611 0.273472897570598 PROSER2 other 1 1 1 0.143848614857377 1.09648256540611 3.90952779136216e-11 147.396822910957 20.718402578396 7.11429476057457 4.64748799169686e-12 177.798118943336 42.6923779876024 4.16463376659337 3.76039177355058e-05 USP6NL other 2.90751581843604e-07 0.308629820008923 4.46065897443064e-08 7.11429476057457 4.16463376659337 6.77895795072952e-28 239.584709220903 21.2548529927474 11.272000295775 4.89055246990803e-26 127.618604272622 41.6901563168547 3.06112079078551 0.00234139012228077 COMMD3 other 6.08750423975511e-24 1 4.80105535970871e-22 11.272000295775 3.06112079078551 3.11596370794796e-47 253.402125053953 22.0335474204815 11.5007411297919 6.47000256440932e-27 -140.462472936793 43.4303145626997 -3.23420344409455 0.0013125832792503 MSRB2 other 2.95829594432579e-43 1 6.35548351901928e-23 11.5007411297919 -3.23420344409455 1.17017557488517e-36 61.8044001507887 5.9183598886422 10.4428255992672 6.19369554012172e-23 -20.0800093375247 11.4878831229853 -1.74792945946222 0.0811801470714785 PDSS1 other 1.08358258234367e-32 1 6.07291847708934e-19 10.4428255992672 -1.74792945946222 7.27523922013642e-20 590.470226480357 134.008828532914 4.40620392659675 1.32438155409868e-05 -1356.72304305638 276.831038744169 -4.9009065212163 1.3456111109214e-06 FAM171A1 other 6.20068638732227e-16 0.0118198479983336 0.114532516798454 4.40620392659675 -4.9009065212163 7.87044259180305e-40 152.435494506514 20.2120201054251 7.54182381134674 2.69746839833405e-13 -271.307557759758 41.662868643529 -6.51197496939274 2.0370866835067e-10 MINDY3 other 7.34548407092979e-36 1.92260241189363e-06 2.60278725755252e-09 7.54182381134674 -6.51197496939274 2.33137171543517e-09 -62.4111074561405 32.7752708746017 -1.90421332274951 0.0575388621222693 265.20494883041 66.1017121298971 4.01207382207065 7.0800255788807e-05 SLC39A12 other 1.63638980706394e-05 0.569800458588319 1 -1.90421332274951 4.01207382207065 1.27539089245617e-15 554.039822116353 77.7945480542989 7.12183354712268 4.39862136607104e-12 -2.32742130968017 158.402136172376 -0.0146931181985288 0.988283699901035 RSU1 other 1.03612756103139e-11 1 4.2226765114282e-08 7.12183354712268 -0.0146931181985288 0.373570946350337 -2.17338253382534 1.65388479335491 -1.31410757421418 0.189497797571756 -3.84162361623615 3.33507914342275 -1.15188379376615 0.249997170548028 ST8SIA6 other 1 1 1 -1.31410757421418 -1.15188379376615 1.25345186428572e-17 257.430212427951 76.092084246807 3.38314050634975 0.000782258333045089 -705.93110518205 142.12155009341 -4.96709404533001 9.823386300668e-07 PARD3 other 1.04462678369572e-13 0.00866127970129898 1 3.38314050634975 -4.96709404533001 1.26771135925227e-13 1102.58134140499 376.970196369875 2.92485016593504 0.00362559352067093 -3100.91200404595 719.321541375034 -4.31088438991878 2.01115643339097e-05 ZEB1 other 9.96421128372286e-10 0.167509219337134 1 2.92485016593504 -4.31088438991878 1.00118948803181e-25 -202.498134006075 257.768628599023 -0.785580988294256 0.432539698618496 -2608.83465293011 332.769209141684 -7.83977177353372 3.49658003411109e-14 FAM13C other 8.89456741167463e-22 3.38503913102294e-10 1 -0.785580988294256 -7.83977177353372 1.31953358465714e-05 27.5828906216659 27.3094422669986 1.01001296005952 0.313046708335907 -76.1280252641331 35.1701101069079 -2.16456602020079 0.0309605084582303 NRBF2 other 0.0724291984618304 1 1 1.01001296005952 -2.16456602020079 3.39932859685776e-16 -413.029539744404 296.69951590993 -1.39208026166712 0.16460612068986 -2219.37396830447 358.155100765516 -6.19668396055455 1.33411861065481e-09 CDHR1 other 2.78574978512493e-12 1.24780113654544e-05 1 -1.39208026166712 -6.19668396055455 8.38985113487021e-09 -105.470576783143 134.670984713009 -0.783172240166707 0.433950194763675 -689.532832359418 162.565482967357 -4.24156973407371 2.71109380154222e-05 RGR other 5.75375990829399e-05 0.224587010519758 1 -0.783172240166707 -4.24156973407371 4.01214786634106e-20 142.352905054324 62.7961376914073 2.26690542265314 0.0238838988345473 -297.604208490788 76.1372607602898 -3.90878533741532 0.000107485146470873 POLR3A essential 3.43199128486814e-16 0.852357211514024 1 2.26690542265314 -3.90878533741532 9.47236626284117e-21 121.182971525234 44.9142474867357 2.69809644614489 0.00724312806017661 -198.374294992562 54.5344575892338 -3.6375954536261 0.000307963289986612 HERC4 other 8.15381287905368e-17 1 1 2.69809644614489 -3.6375954536261 0.000515417358541171 -599.127906018138 441.065883189996 -1.35836374757658 0.175047501698852 -1750.6286067601 534.702444511091 -3.27402394496402 0.00114434609322367 CAMK2G other 1 1 1 -1.35836374757658 -3.27402394496402 0.687856900273015 -82.6855215716451 97.9393101354034 -0.844252644391005 0.398990171311344 -94.2069588582936 117.752267436841 -0.800043692651811 0.424120169133536 ADIRF other 1 1 1 -0.844252644391005 -0.800043692651811 5.04927191431846e-22 -955.090399352948 1190.13415283698 -0.802506504898003 0.422696238642081 -9546.018628244 1430.89628522837 -6.67135607716005 7.68847001549643e-11 GLUD1 other 4.39438134703136e-18 7.28174995167667e-07 1 -0.802506504898003 -6.67135607716005 0.270540206730807 2.11931430605133 4.89321159703485 0.433113153605615 0.665145770437202 -3.08124467744042 5.90873082252909 -0.521473184341399 0.602300751279653 HTR7 other 1 1 1 0.433113153605615 -0.521473184341399 1.5281246962221e-44 93.4322462012996 20.9327507222935 4.46344808863528 1.02705608144645e-05 -125.779314503771 25.2770571924754 -4.9760268193409 9.34328793005083e-07 RPP30 essential 1.44285533817291e-40 0.00825105757102789 0.089169008991181 4.46344808863528 -4.9760268193409 1.4898539458601e-47 73.6898711588596 56.1358738607707 1.31270551415351 0.189972744614655 -555.780059959312 67.4022495162347 -8.24571974894465 1.95213361176999e-15 FRA10AC1 other 1.41536124856709e-43 1.89864515080749e-11 1 1.31270551415351 -8.24571974894465 3.11447406936811e-07 -798.089234483242 794.616693979695 -1.00437008249368 0.315756068857427 -3584.73318872014 946.65062639888 -3.78675415063812 0.00017397392835108 ADD3 other 0.00195059510964525 1 1 -1.00437008249368 -3.78675415063812 0.872559409017884 -1.52513382579318 15.3824630675697 -0.099147569481806 0.92106656728634 -5.92464795694955 17.4582162389712 -0.339361586307095 0.734500378898739 VAX1 other 1 1 1 -0.099147569481806 -0.339361586307095 6.0084352656272e-39 40.4860445446896 58.2133050957544 0.695477511165095 0.487124918595075 -578.42499884394 70.6820484705012 -8.18347814417606 3.02841128277517e-15 DNAJB12 other 5.5926515452458e-35 2.94240440234436e-11 1 0.695477511165095 -8.18347814417606 9.33220203082187e-24 427.929517902458 262.864388988632 1.6279478538303 0.104255009472037 -1638.24869813225 319.167473021872 -5.13288112545224 4.29853229746473e-07 EIF4EBP2 other 8.20393880529551e-20 0.00383901919486575 1 1.6279478538303 -5.13288112545224 0.247491524495812 -12.8523998854163 9.9990178697636 -1.2853662282454 0.199346666392738 -20.2921376625208 12.1437997646658 -1.67098750438588 0.0954417259832435 NPFFR1 other 1 1 1 -1.2853662282454 -1.67098750438588 0.339280936375998 -6.72169439795192 33.2271091538272 -0.202295492118601 0.839779867085208 21.1721719011522 38.0059531369605 0.557075146223933 0.577761283748655 PLEKHS1 other 1 1 1 -0.202295492118601 0.557075146223933 2.16226771847675e-18 74.5873786407754 82.7680685984927 0.901161279993112 0.367998947019303 -375.515887025599 94.7293961965224 -3.96409036796314 8.60507492954472e-05 TCF7L2 other 1.81933205832634e-14 0.688405994363578 1 0.901161279993112 -3.96409036796314 2.86865551627821e-05 351.934211950395 254.14132665333 1.38479725664792 0.166821048994148 1022.69705710738 295.075856309201 3.46587846901213 0.000580759070627599 MKI67 other 0.152268234804048 1 1 1.38479725664792 3.46587846901213 2.99517202091357e-20 -12.5531781294231 11.2338607001715 -1.11744114196035 0.264419712037022 -85.4904733205312 13.4026431885831 -6.37862786598357 4.5564574876742e-10 CYP17A1 other 2.56506531871038e-16 4.28671520440389e-06 1 -1.11744114196035 -6.37862786598357 1.97872709491311e-12 -379.87614758356 496.845717493681 -0.764575670491497 0.444936920153846 -2833.36503262312 594.951158094699 -4.76234896608459 2.60723779793466e-06 INA other 1.514319845737e-08 0.0226464675128604 1 -0.764575670491497 -4.76234896608459 4.38151488029529e-05 78.5774499129995 18.0445610222363 4.35463349959961 1.66972429392347e-05 90.3697454839937 20.4729724889886 4.41409988376622 1.28569540584095e-05 FUOM other 0.227050101096902 0.108268410125866 0.143729867220933 4.35463349959961 4.41409988376622 9.1722040183862e-24 136.218555292842 37.9202778226186 3.592235160566 0.000365287220658667 -86.9007745683814 43.2888603984951 -2.00746274603714 0.0453184341587642 LRRC27 other 8.06511899336699e-20 1 1 3.592235160566 -2.00746274603714 8.00767957662873e-10 198.763651700226 78.1045534700966 2.54484076624708 0.0112836997768754 -68.9923288620586 88.6286197297879 -0.778443002637335 0.436739039830371 MTG1 other 5.72148705750123e-06 1 1 2.54484076624708 -0.778443002637335 0.871273776598896 29.2629147349763 172.023947503725 0.170109540907626 0.86500325801085 -19.2953297583686 196.407048693679 -0.09824153403202 0.921785858583318 NKX6-2 other 1 1 1 0.170109540907626 -0.09824153403202 0.489190449306375 13.1913268711362 19.5788881197139 0.673752604871056 0.500833146935953 2.30156007259377 22.2170123609829 0.103594490348114 0.917539797110908 PAOX other 1 1 1 0.673752604871056 0.103594490348114 4.17828137477094e-05 137.31620896505 97.2690521215151 1.41171529864921 0.158745424299052 -134.593175890154 116.22674867894 -1.15802237798072 0.247487397098123 GSTO1 other 0.217395979929332 1 1 1.41171529864921 -1.15802237798072 3.9532677049608e-17 30.8725965702409 11.1203764045034 2.77621866807841 0.00573579901299238 -32.041517723572 13.3161675493206 -2.4062116675009 0.0165331629178902 TAF5 other 3.2772589274125e-13 1 1 2.77621866807841 -2.4062116675009 7.96114875343124e-18 143.412016847442 73.0829295076151 1.96231894114888 0.050358056879531 -303.072819213042 88.0199469546884 -3.44322883276742 0.000630097545393233 PPRC1 essential 6.6459669793644e-14 1 1 1.96231894114888 -3.44322883276742 0.0018747332822097 27.6520678886906 82.81983541954 0.333882188350335 0.738628619251015 218.634483503707 98.9613858363987 2.20929084264392 0.0276723735382535 ITPRIP other 1 1 1 0.333882188350335 2.20929084264392 8.73076595325939e-29 5.42813462018324 132.026663154849 0.041113927221025 0.967223848808574 -1047.98316277006 157.335009197231 -6.66083898375307 8.20486249140318e-11 CNNM2 other 7.86467397069606e-25 7.76590234811311e-07 1 0.041113927221025 -6.66083898375307 1.27568663767494e-19 209.776632600043 91.8565430348465 2.28374186170344 0.0228657294452471 -363.973599672449 109.994218995865 -3.30902481053239 0.00101370019886044 PDCD11 essential 1.08560932866137e-15 1 1 2.28374186170344 -3.30902481053239 1.09260396846201e-26 -60.0508333992121 55.7585440463537 -1.07697993959975 0.282084760651776 330.639666191966 64.7495471400448 5.10643982539115 4.91511160893398e-07 ADAM12 other 9.75586083439731e-23 0.00438182199936464 1 -1.07697993959975 5.10643982539115 0.00974416721817445 115.01191012621 124.070022695233 0.926991932682455 0.3544423979554 331.965735264117 144.145332639075 2.30299329979226 0.0217480693649556 RGS10 other 1 1 1 0.926991932682455 2.30299329979226 3.43332375548788e-05 83.2264264485542 45.8393211576975 1.81561210651957 0.0701135496033758 -95.2315774884113 55.8372793339751 -1.70551965683733 0.0888065330762129 BTBD10 other 0.180425000385338 1 1 1.81561210651957 -1.70551965683733 0.315423067388639 -13.3746887308154 79.5642333364036 -0.168099259805172 0.866582782553635 -112.886831949363 96.4933973408795 -1.16989177560586 0.242680715283893 ADM other 1 1 1 -0.168099259805172 -1.16989177560586 0.131150599693125 5.5044263942819 11.1855153824169 0.492103064194483 0.622894165792512 -15.7867663482356 13.9275666205507 -1.1334906361131 0.257631149663207 GAS2 other 1 1 1 0.492103064194483 -1.1334906361131 0.00278149432141511 -1.52699499432012 4.05016820486917 -0.377020142641074 0.706342488533319 -14.2650372854199 5.05209659607671 -2.82358759658271 0.00496702795245342 SLC5A12 other 1 1 1 -0.377020142641074 -2.82358759658271 7.42435337085488e-19 97.0705418986818 30.2204448059367 3.2120818380414 0.00141562914558514 -179.91519987324 37.827403520578 -4.75621330381205 2.68734658955299e-06 LIN7C other 6.27951808106906e-15 0.0233234810507304 1 3.2120818380414 -4.75621330381205 5.34810857631956e-06 179.111616241349 91.0518313107069 1.96713908619966 0.0498037346848689 -288.595229249334 117.924526866094 -2.44728757383136 0.0147890484712851 LRRC4C other 0.0305697886222426 1 1 1.96713908619966 -2.44728757383136 1.3077279549058e-16 47.3808876228981 10.740272761837 4.41151623180881 1.29498269291709e-05 -41.16071855187 13.4665158809321 -3.05652322514626 0.00237682163572261 IMMP1L other 1.07691397086493e-12 1 0.112028952764257 4.41151623180881 -3.05652322514626 1.21401355402192e-21 96.0429084470169 30.2974422298954 3.17000054718311 0.00163183169022749 -137.822409229048 35.082004821114 -3.92857848152681 9.93240348902901e-05 PGAP2 other 1.05303535675862e-17 0.7907186417616 1 3.17000054718311 -3.92857848152681 1.16572342646374e-06 -6.00666411385956 7.77359677098979 -0.772700757553539 0.440118168901664 -39.1765893638042 9.4096873318732 -4.16343157663723 3.77948959247808e-05 ZNF214 other 0.00702115219759108 0.310107121062827 1 -0.772700757553539 -4.16343157663723 5.43126484774963e-06 -3.75055162232527 4.09383662267495 -0.916145896382798 0.360095657170067 -19.9040693059878 4.95095137706429 -4.02025142040277 6.8471819295109e-05 ZNF215 other 0.0310233848103459 0.551472032602808 1 -0.916145896382798 -4.02025142040277 5.04796283129572e-11 502.667229631361 191.829378141912 2.62038710910848 0.00909181089123147 -943.497018481614 250.49717032992 -3.76649771028938 0.000188438548123536 HSD17B12 other 3.74558842082143e-07 1 1 2.62038710910848 -3.76649771028938 1.68017769327704e-13 74.2596779699458 17.0716207114225 4.34989033702343 1.69703562844583e-05 -47.9995807377637 21.4018792532907 -2.24277411201558 0.0254119362326235 APIP other 1.31658724045189e-09 1 0.146012945471479 4.34989033702343 -2.24277411201558 0.0773272454272199 -246.462909038419 165.452597233578 -1.4896285290129 0.137043284584388 -470.65543288253 207.420055072283 -2.26909318252043 0.0237494036651048 PAMR1 other 1 1 1 -1.4896285290129 -2.26909318252043 0.667589519721189 -116.30910167045 210.111638111495 -0.553558587786229 0.580166034031451 -251.878778237354 280.96578959164 -0.896474900390681 0.370496160812966 DGKZ other 1 1 1 -0.553558587786229 -0.896474900390681 3.3655534499588e-15 805.034742258569 167.978540161639 4.79248564420145 2.26285712159643e-06 -470.751934209319 210.617153670462 -2.23510728354952 0.0259160213771886 EIF3M essential 2.71600163411675e-11 1 0.0200896455255331 4.79248564420145 -2.23510728354952 0.285451454668831 -845.95108056023 535.92982559707 -1.57847359888539 0.115182058877452 -471.901734429288 1278.07516083033 -0.369228468631458 0.71213668413471 SERPING1 other 1 1 1 -1.57847359888539 -0.369228468631458 0.0504965817176025 13.2267324365003 13.9688071314027 0.946876301754203 0.344226294289509 -61.0190135462725 33.3125431136165 -1.83171285777131 0.0676762807853446 SLC43A1 other 1 1 1 0.946876301754203 -1.83171285777131 0.0106671404679412 361.082097695616 165.170256096143 2.18612058992895 0.0293403156475468 -134.791508868775 216.766401271098 -0.621828420264258 0.534381205203001 PTPRJ other 1 1 1 2.18612058992895 -0.621828420264258 3.98643082090064e-16 477.185696989446 107.398300191826 4.44314012546878 1.12494566086071e-05 -523.231309227225 137.501657141091 -3.805272751661 0.000161846046912665 C11orf49 other 3.26249498382508e-12 1 0.097532788796624 4.44314012546878 -3.805272751661 4.05862914668718e-16 832.697309599752 175.956372975367 4.73240778676614 3.00115297444972e-06 -787.186436238331 225.276310941931 -3.49431519429153 0.000523783766054025 ARFGAP2 other 3.32117623073412e-12 1 0.0265687507866937 4.73240778676614 -3.49431519429153 1.17807591378556e-06 443.507064484493 123.73956180594 3.58419779423531 0.000376293899587774 -201.54037942871 162.559280568619 -1.23979620679753 0.215717645813341 CELF1 other 0.00709201700098905 1 1 3.58419779423531 -1.23979620679753 0.000332757996344598 193.47223738894 49.3970329580185 3.91667729422874 0.000104109358075988 38.9731556646563 119.656595856968 0.325708377256887 0.744800549159045 TKFC other 1 1 0.864134797856886 3.91667729422874 0.325708377256887 0.00388994747234555 81.6842304759249 24.3638185197055 3.35268588582937 0.000869793648643092 63.9294574727796 59.0175444064133 1.08322801491945 0.279303171803751 TMEM138 other 1 1 1 3.35268588582937 1.08322801491945 0.0262908033436177 114.022396983077 42.3208355193802 2.69423785196447 0.00732673730375923 61.4941409124375 101.725718421381 0.604509281101447 0.545818825126688 INCENP essential 1 1 1 2.69423785196447 0.604509281101447 0.000387011037100365 -72.6357482426208 77.9261536494143 -0.932110014943189 0.351793175892809 126.856718616321 99.5671576895379 1.27408195192108 0.203309979648695 PLCH2 other 1 1 1 -0.932110014943189 1.27408195192108 2.67159973506043e-06 617.99013586871 141.691842126737 4.36150823218139 1.61213759477899e-05 -403.334365171406 343.226353372226 -1.17512644704759 0.240582550233731 CPSF7 other 0.0156662608463944 1 0.13888565379021 4.36150823218139 -1.17512644704759 0.919019716755548 6.92081200220878 18.2849142234804 0.37849846696691 0.705244559802091 2.32106033237548 29.7633164707748 0.0779839281235536 0.937876613067412 HMGA2 other 1 1 1 0.37849846696691 0.0779839281235536 1.27223298665531e-11 59.7766432270834 24.0929591071619 2.4810834966849 0.0134735908761174 -196.803593644134 47.2495108126055 -4.16519854405835 3.7498845780483e-05 MKX other 9.57100875860786e-08 0.307940521549326 1 2.4810834966849 -4.16519854405835 0.0159781377819114 -16.5747189355342 8.36097587177091 -1.98239047567346 0.0480614329034952 -46.9209804049164 16.396990427786 -2.86156051694737 0.00441800494747609 MPP7 other 1 1 1 -1.98239047567346 -2.86156051694737 0.000100358484840139 4.88407647927253 1.49658841148261 3.26347340511215 0.00118715781113982 -1.14759644766709 2.83277747022417 -0.405113518350694 0.685592764963975 CCDC7 other 0.497878443291932 1 1 3.26347340511215 -0.405113518350694 1.02349662112116e-07 293.905280382407 184.98797487351 1.58878046307265 0.112834820392948 1897.72414906344 349.170404247473 5.43495131883638 9.13796715250794e-08 ITGB1 other 0.000659541222650476 0.000830184315805347 1 1.58878046307265 5.43495131883638 3.29349057686368e-21 73.0537374681938 291.624296896748 0.250506347535435 0.802314341590582 -2261.04766851937 373.066568431923 -6.06070835567773 2.94496517113124e-09 PCDH15 other 2.8485399999294e-17 2.74029009173762e-05 1 0.250506347535435 -6.06070835567773 0.00126421662555834 189.899433849077 190.555310059122 0.996558079594627 0.3195305469851 -360.295739491265 245.965408903834 -1.46482280210439 0.143688308179761 ARID5B other 1 1 1 0.996558079594627 -1.46482280210439 0.547242643303383 -38.6842133441845 47.3349271531269 -0.817244594441698 0.414232968850222 -106.607933839459 109.24762572177 -0.975837535462476 0.329683618117482 CDH8 other 1 1 1 -0.817244594441698 -0.975837535462476 7.01297111312773e-20 134.187848913171 23.1923299832676 5.78587183823196 1.39709791194516e-08 -82.6016896305976 32.780505619932 -2.5198418410109 0.0121045644140366 DCUN1D2 other 5.9792591710527e-16 1 0.000129678628186749 5.78587183823196 -2.5198418410109 1.8305959460785e-10 242.075870055821 76.7603781147429 3.15365656086219 0.00172623441295107 -294.108096270344 108.494662157438 -2.71080706112122 0.0069825792543497 TMCO3 other 1.33615198104269e-06 1 1 3.15365656086219 -2.71080706112122 0.0140199015300073 3.3285139150717 21.8123958147874 0.152597355344853 0.878787221180821 -47.4183595871808 26.8936553460123 -1.76318016190432 0.0785786826286292 EEF1AKMT1 other 1 1 1 0.152597355344853 -1.76318016190432 0.842055630437868 -13.3211498621952 38.5055119089098 -0.345954363461216 0.729545427961623 -26.8836021193253 47.1060703842445 -0.570703561134173 0.568497334014253 LATS2 other 1 1 1 -0.345954363461216 -0.570703561134173 4.68333151878779e-27 94.5060988651696 180.529042982904 0.523495263164494 0.600898073860979 -1608.57273110605 220.851856878839 -7.2834919925012 1.55398869696192e-12 SAP18 essential 4.18924004355568e-23 1.49276154230162e-08 1 0.523495263164494 -7.2834919925012 5.76369173541971e-06 1115.68303471266 349.788968812608 3.18958896416874 0.00152851127933817 -657.293647232278 564.123316938852 -1.16515950944734 0.244597390604601 ADGRL3 other 0.0327896422828027 1 1 3.18958896416874 -1.16515950944734 1.63484019356659e-16 47.1042916996946 9.53345386388416 4.94094715013423 1.10934461821523e-06 -55.3540482391574 17.1113954387773 -3.23492309187805 0.00130914124087534 KIAA1328 other 1.34481954322787e-12 1 0.00993307171149917 4.94094715013423 -3.23492309187805 0.0355948884499975 -49.0358414065816 73.5441848306883 -0.666753483221967 0.50528228683116 -176.594756920257 85.3395997227867 -2.06931784885211 0.0391048824319064 FAM124A other 1 1 1 -0.666753483221967 -2.06931784885211 0.03871154460386 19.9510554361594 42.4930713875518 0.469513141429546 0.638937071336549 -47.6382101255133 50.5290941950955 -0.942787732184148 0.346310394956258 ADRA2A other 1 1 1 0.469513141429546 -0.942787732184148 2.00897441417011e-09 -3390.11507546176 2147.32138909585 -1.57876463797028 0.115115254315032 -15872.2645301349 2909.00751341977 -5.45624734790589 8.16959270434706e-08 GPM6A other 1.41331350036868e-05 0.000743269544241495 1 -1.57876463797028 -5.45624734790589 5.26664380958706e-05 57.6963328552439 47.2842733434575 1.22020132224845 0.223048125901479 -132.871481662831 64.0566927341178 -2.07427945451922 0.0386396460366156 WDR17 other 0.270073494555625 1 1 1.22020132224845 -2.07427945451922 0.677743734088656 7.09297206418263 8.32459004869733 0.852050614227251 0.394653767747354 5.2195563721136 11.2774432000589 0.462831537212828 0.643716035669056 VEGFC other 1 1 1 0.852050614227251 0.462831537212828 8.2869411926352e-07 37.2474902811179 20.7331826040806 1.79651580716734 0.0731014359880947 -79.1758677610636 31.3312525132143 -2.52705721635834 0.0118532571100119 CCDC102B other 0.00504884307530491 1 1 1.79651580716734 -2.52705721635834 0.43373760480544 6.37684824459484 11.940671150895 0.534044373554067 0.59358176924576 -9.18273984462216 18.0443200713581 -0.508899188681428 0.611079139123036 CD226 other 1 1 1 0.534044373554067 -0.508899188681428 0.506712191936603 422.01787314685 364.997848663349 1.15622016593334 0.248225715274302 494.007647511703 544.031400016379 0.90804988001948 0.364354645238671 CNDP1 other 1 1 1 1.15622016593334 0.90804988001948 0.714668919362906 1.21183069232198 5.95311939226976 0.203562302798019 0.838790526691327 -4.67017667331954 9.3343521062401 -0.500321459932659 0.617101183051855 FSIP1 other 1 1 1 0.203562302798019 -0.500321459932659 0.00503053956155901 -7.11327134404079 37.1290212116224 -0.191582517176998 0.848158836865048 -235.76627218935 80.1132123853184 -2.9429137238361 0.00342573860414729 MTMR12 other 1 1 1 -0.191582517176998 -2.9429137238361 4.66945066045261e-06 382.239228026937 198.718552282237 1.92352059552069 0.055065513147837 -834.094329034813 329.687694859577 -2.52995286763759 0.0117589228745779 CCT5 essential 0.0268353329456212 1 1 1.92352059552069 -2.52995286763759 8.04693818247189e-12 20.9141102944412 16.9651379579756 1.23276983342237 0.218325938416685 -141.577714449187 28.1463263600862 -5.03006014489891 7.17877177057752e-07 FAM173B other 6.07382894012978e-08 0.00636326329743991 1 1.23276983342237 -5.03006014489891 3.08680170146337e-08 -120.473589726705 208.287718042924 -0.578399873303512 0.563292133026315 -865.186558876685 241.836609454875 -3.57756652653586 0.000385593563730956 DOCK1 other 0.000205272313147314 1 1 -0.578399873303512 -3.57756652653586 0.0415467455805269 70.579943926087 244.776375585227 0.288344591087845 0.773220003382808 -913.759835451022 482.478594404732 -1.89388678803127 0.058901703786402 PIP4K2A other 1 1 1 0.288344591087845 -1.89388678803127 0.167860745677536 237.14181464364 199.273539724534 1.19003162673505 0.234678587168785 -7.84979645524448 241.314275670068 -0.0325293496766721 0.974064728645983 FREM2 other 1 1 1 1.19003162673505 -0.0325293496766721 0.00233277209451296 89.6218629322169 137.953124543233 0.649654462187482 0.516255992678886 -283.685004933466 166.815026014548 -1.70059623351151 0.0897286540251222 FOXO1 og 1 1 1 0.649654462187482 -1.70059623351151 0.132856791918966 40.0325886938811 56.7523417600405 0.705390957489409 0.480942790257598 -76.7231603316235 78.4474182396477 -0.978020208354635 0.328605432754495 SEC24D other 1 1 1 0.705390957489409 -0.978020208354635 0.000319975684017467 213.351223853177 56.5092166495846 3.77551196959912 0.000181855555523894 32.5816540039149 115.330410878028 0.282507048712182 0.777689113047269 ABCB9 other 1 1 1 3.77551196959912 0.282507048712182 0.00357640147638276 96.5878381143351 29.7132467848065 3.25066590042674 0.0012406061446765 128.207922412735 60.0954808018161 2.13340372191283 0.0334492891269047 RILPL2 other 1 1 1 3.25066590042674 2.13340372191283 9.11960078146475e-09 216.429379338739 34.9383911028419 6.19460062432966 1.34799738824079e-09 109.73409462597 64.334823502236 1.70567180653191 0.0887781590698529 DHX37 essential 6.23871889460004e-05 1 1.2691395410287e-05 6.19460062432966 1.70567180653191 0.000582035382909395 11725.1606777295 3132.54164297243 3.74301829443636 0.000206050295178471 13389.1802570937 5768.19674153922 2.32120727794746 0.020733812501015 UBC other 1 1 1 3.74301829443636 2.32120727794746 0.108124253431242 -346.415992384584 253.463794481656 -1.36672771388521 0.172418244595338 459.383379343167 527.173151965933 0.871408905461205 0.384012704284036 ITPR1 other 1 1 1 -1.36672771388521 0.871408905461205 2.57178902795105e-05 -93.5508517097978 297.447676424733 -0.314511960000031 0.753281993744145 -1472.17835304924 404.504404595146 -3.63946186079899 0.000305805372859699 SLC7A11 other 0.137179226750909 1 1 -0.314511960000031 -3.63946186079899 0.0191467747988415 -1.06305118763136 6.61842681838163 -0.160619920232237 0.872466816881715 -19.7173190913963 9.00051676888271 -2.19068744581029 0.0290007355193821 NOCT other 1 1 1 -0.160619920232237 -2.19068744581029 1.16766045622246e-07 146.783609496545 38.6138089547982 3.80132427931084 0.000164461225987149 431.147967413064 75.3295607628033 5.72348973028871 1.94626787618372e-08 ENKUR other 0.00074823682034735 0.000179017719251378 1 3.80132427931084 5.72348973028871 1.27909507025631e-11 -283.323978485298 150.994749516655 -1.87638298280065 0.0612719900218078 -2013.65410075862 294.567370235195 -6.83597134044694 2.76537056110249e-11 GPR158 other 9.62135311846796e-08 2.62959086655236e-07 1 -1.87638298280065 -6.83597134044694 0.186099132168396 -50.9985150573182 112.92387190482 -0.45161854793912 0.651768369527548 -414.887441344763 230.461698314689 -1.80024465834772 0.0725130863950337 THRB other 1 1 1 -0.45161854793912 -1.80024465834772 0.000197707077117385 125.714004600634 30.2955679772094 4.14958401490296 4.00294464638803e-05 90.7235839387793 60.1128169592476 1.50922196842453 0.131963067436736 NGLY1 other 0.941594124916003 1 0.338849264316747 4.14958401490296 1.50922196842453 4.02142298885153e-05 39.8426811214616 11.6750966602355 3.41262109265123 0.000703203140017076 -26.331181816111 23.1658620510506 -1.13663725347604 0.25631143691233 OXSM other 0.209596566178942 1 1 3.41262109265123 -1.13663725347604 3.75208672922259e-15 120.616535223209 40.0103103058254 3.01463633501607 0.00272271079907248 -196.726483932976 50.1651848826822 -3.92157398389036 0.000102120421240941 UEVLD other 3.0256827384451e-11 0.811755228444237 1 3.01463633501607 -3.92157398389036 0.934982950394564 -11.7219225861696 32.0464225579685 -0.365779442774491 0.714706655550966 -8.96854381075525 40.1800111061618 -0.223209092378271 0.82347707432332 TMEM86A other 1 1 1 -0.365779442774491 -0.223209092378271 6.97856579412129e-09 89.8008137069506 38.9278980177719 2.30684979872156 0.0215289340770464 -240.505409704999 67.4047085990826 -3.56808025290198 0.000399315124828049 C12orf45 essential 4.80264897951427e-05 1 1 2.30684979872156 -3.56808025290198 1.71896055028137e-08 187.07800294532 86.6028988320012 2.16018176606568 0.0313003797024008 -509.689909079263 146.715557532557 -3.47400042402565 0.000563801307933775 TMEM263 other 0.000116098595566003 1 1 2.16018176606568 -3.47400042402565 0.0153832822357293 -105.928764348413 69.2623343330431 -1.52938484341376 0.126890920978594 131.160947762568 115.856713703111 1.13209622101551 0.258213378115316 BTBD11 other 1 1 1 -1.52938484341376 1.13209622101551 3.50756066018643e-09 68.4263448120643 52.8865266794518 1.29383321439882 0.196404872491087 -385.286333967628 88.4645202801091 -4.35526392668698 1.65681438772578e-05 UBE3B other 2.44056070735772e-05 0.138625659821016 1 1.29383321439882 -4.35526392668698 0.00420580518285152 -336.230333119994 260.543181330018 -1.29049753443406 0.197561900911222 -988.258469052341 336.351048107245 -2.93817567869518 0.00347666206600438 ANK3 other 1 1 1 -1.29049753443406 -2.93817567869518 3.34714687848882e-28 38.9528151466764 30.4653978043689 1.27859204060977 0.201720922994595 -260.202062970306 39.329635994289 -6.61592858393322 1.0845319598796e-10 IPMK other 3.010089187825e-24 1.02499115528221e-06 1 1.27859204060977 -6.61592858393322 0.00706108647585098 2.82016655413013 2.56644624596281 1.09886055808355 0.272432539264196 -7.68198187138086 4.29295418377323 -1.78943951939149 0.0742348350680121 RAD9B other 1 1 1 1.09886055808355 -1.78943951939149 0.047625508799789 47.6365110523173 135.199953530443 0.352341179182365 0.724752657781469 -479.614150379791 249.561369855452 -1.92182848915114 0.0552787911541789 PLBD2 other 1 1 1 0.352341179182365 -1.92182848915114 4.80414224157085e-21 376.02512990083 408.787512350072 0.919854737585074 0.358156145654129 -2616.16160840812 495.634963670806 -5.27840406784888 2.05711938966414e-07 DLG5 other 4.1498180682689e-17 0.00185243601039256 1 0.919854737585074 -5.27840406784888 0.0265617565206987 153.280187314583 244.215292760915 0.627643689228924 0.530582574494213 -524.608931767474 339.872681752039 -1.54354545079387 0.1234606570481 SLC2A13 other 1 1 1 0.627643689228924 -1.54354545079387 0.42844272185174 31.7293933150483 38.4014723062206 0.826254604563911 0.409120031814888 -15.0833256781409 58.1214280846483 -0.259514023918571 0.795363443022799 GXYLT1 other 1 1 1 0.826254604563911 -0.259514023918571 3.93744574260322e-10 201.713796471291 94.9873815078863 2.12358518857101 0.0342752256868975 -531.266099265592 145.158957586724 -3.65989194258434 0.000283689899343681 TWF1 other 2.84716701647639e-06 1 1 2.12358518857101 -3.65989194258434 3.20921369953771e-30 270.624238266526 61.7648109977504 4.38152782943646 1.48489696864403e-05 -1033.29156982528 132.074167022635 -7.82357059763391 4.07127456255892e-14 DIP2C other 2.90562208356144e-26 3.94017952164452e-10 0.128087212515234 4.38152782943646 -7.82357059763391 9.67707422583014e-10 66.5292454234288 50.6693804122471 1.31300688664723 0.189869679981782 -277.540168766094 71.4021138000794 -3.88700213474331 0.000117242267987373 EIF4E essential 6.89394767848139e-06 0.926682886172193 1 1.31300688664723 -3.88700213474331 0.0654416325403089 -66.7501327467156 144.464011622821 -0.462053711487624 0.644272746308995 -533.153960909247 244.932135905058 -2.17674156532858 0.03003449622448 MAGI1 other 1 1 1 -0.462053711487624 -2.17674156532858 2.4933475389937e-07 105.834728210928 28.9745947454844 3.65267328639419 0.000291006476597451 -27.516563228953 38.7737411792529 -0.709670059996083 0.47828724346262 TEX30 other 0.00157055961481213 1 1 3.65267328639419 -0.709670059996083 5.6182019075486e-13 -80.0435224386338 338.729852945437 -0.236304895309972 0.813306805549427 -2637.74490544739 461.312135898164 -5.717917869886 2.00110993749591e-08 AKAP6 other 4.35017373701488e-09 0.000184022069852124 1 -0.236304895309972 -5.717917869886 4.80288604873014e-08 104.561049957655 190.513596342647 0.548837731085595 0.583397114319842 -995.319918918237 259.458188530622 -3.83614764504057 0.000143383170759444 NPAS3 other 0.000315453555680596 1 1 0.548837731085595 -3.83614764504057 7.93881734353637e-16 132.485037346008 65.8396436496324 2.01223806816196 0.0448093645284527 -404.262282956639 88.1731512528746 -4.58486826445889 5.94274358468909e-06 MBIP other 6.46457896284166e-12 0.0508579995977692 1 2.01223806816196 -4.58486826445889 7.14228332482353e-11 76.1381079003414 19.2268279965043 3.95999318838159 8.75489895997066e-05 -32.6449950221169 25.4860564836146 -1.28089628315408 0.200912572094957 MIPOL1 other 5.27814737704459e-07 1 0.730071024271953 3.95999318838159 -1.28089628315408 3.30153420670942e-06 169.255121722833 84.0130695834056 2.01462846866703 0.0445656309241081 -289.667930822674 110.07066989679 -2.63165410998486 0.00880258025195166 EXT2 ts 0.0192048251054558 1 1 2.01462846866703 -2.63165410998486 0.682791274687792 15.6148713060055 17.8778882206094 0.873418108074134 0.382919343898677 15.4664515655928 38.5762303056227 0.400932165819698 0.688667833112229 ADAMTS12 other 1 1 1 0.873418108074134 0.400932165819698 5.16342576064188e-10 28.110753598646 16.632827727465 1.6900766399587 0.0917264463612269 -78.4614374053828 22.6520491721143 -3.46376775051205 0.000585211016052224 NUBPL other 3.72076460311854e-06 1 1 1.6900766399587 -3.46376775051205 1.21551430663654e-21 22.347428563399 44.6303059637345 0.500723176344746 0.616817475877645 -267.320308656724 51.5158407230596 -5.18908950925973 3.23892105407242e-07 VIPAS39 other 1.05421555814587e-17 0.00290207326444889 1 0.500723176344746 -5.18908950925973 0.127351798658305 118.912483574245 74.0127893698226 1.60664777785999 0.108852292176603 7.4959827294921 104.04190244463 0.0720477283994433 0.942596811639078 ANKRD50 other 1 1 1 1.60664777785999 0.0720477283994433 3.40679861825322e-33 197.245476477682 31.6580013415046 6.23050944846246 1.09869661214283e-09 -411.649311838228 65.2442729571168 -6.30935549099909 6.90579475093842e-10 UPF2 essential 3.12233093362908e-29 6.4817789532308e-06 1.03574129626705e-05 6.23050944846246 -6.30935549099909 1.09332967604971e-59 607.317852834734 43.3909578369137 13.9964149931273 5.1794455883376e-37 -297.548516871063 89.4248334392101 -3.32735891617101 0.000951192552071617 CDC123 essential 1.05812446048091e-55 1 5.09709240348304e-33 13.9964149931273 -3.32735891617101 9.48134204585951e-08 118.3691195795 24.159018787393 4.8995830758354 1.35423085012579e-06 26.1332457293034 33.9610261582817 0.769506952101639 0.442007197128717 SCLT1 other 0.000612873949844359 1 0.0120986984150238 4.8995830758354 0.769506952101639 0.0543843780885238 -22.9333243170134 48.5206174745679 -0.472651122567307 0.636698067570597 166.30494539272 98.3132241316115 1.69158266206475 0.0914384907050252 CCDC3 other 1 1 1 -0.472651122567307 1.69158266206475 0.000159987717751743 80.8264126149804 24.3525468973611 3.31901270760879 0.000978817631532103 4.27405669232232 34.2330741774015 0.124851676194006 0.900698256304623 C4orf33 other 0.773540615329675 1 1 3.31901270760879 0.124851676194006 1.21030312013368e-15 185.27021809695 63.9045764209706 2.89916980086816 0.00392958127512036 -664.662745394572 130.691930685596 -5.0857213747461 5.44003984561088e-07 FRMD4A other 9.83613345732641e-12 0.00483837143868631 1 2.89916980086816 -5.0857213747461 7.68367371589126e-22 -0.776213592230492 33.7178354592325 -0.0230208606708753 0.981644140718869 -203.667961165047 38.5906092553784 -5.27765601774379 2.06502601376684e-07 VTI1A other 6.67480735699474e-18 0.00185934942279566 1 -0.0230208606708753 -5.27765601774379 0.295110152076757 459.931894569251 510.288737485936 0.901316961913013 0.367917421109773 -469.017612135779 830.766655273577 -0.564559987041522 0.572663412154587 QDPR other 1 1 1 0.901316961913013 -0.564559987041522 1.25282988218137e-27 68.7777453271028 44.8893358715039 1.53216223835389 0.126204337174215 -236.483223001038 51.3080609101486 -4.60908517698947 5.31303555113088e-06 FAM160B1 other 1.12403897029313e-23 0.0455592798509473 1 1.53216223835389 -4.60908517698947 0.177588628334679 23.5589315136024 29.527664682917 0.797859626441511 0.42538628135935 -50.1540846641845 51.3353238842467 -0.976989738630543 0.329115992584596 ANO4 other 1 1 1 0.797859626441511 -0.976989738630543 0.053482160366966 73.8418931178091 49.7320618021199 1.48479452574519 0.138320871559287 -40.1538905612143 75.8498184838613 -0.529386771963837 0.596806603435704 TEX9 other 1 1 1 1.48479452574519 -0.529386771963837 0.0252463356909473 44.0129839471202 26.1726246303336 1.68164196632041 0.0933510903433815 -56.072541481182 50.6745906854199 -1.1065218430529 0.269108068840032 QTRT2 other 1 1 1 1.68164196632041 -1.1065218430529 6.56446188901067e-14 4.06709175981884 13.8738571630427 0.293147876039318 0.769548277571673 -98.9787937330398 18.5338201244555 -5.34044212517401 1.49423386745884e-07 MMAA other 5.18264266137392e-10 0.00135004029924907 1 0.293147876039318 -5.34044212517401 0.000288648734827657 41.4221684446072 126.484275645385 0.32748867978451 0.743455128798119 -427.4833643729 168.29957802636 -2.54001447529443 0.0114300645268011 ZNF827 other 1 1 1 0.32748867978451 -2.54001447529443 0.0726223171881317 123.921294478047 147.632411312889 0.839390844977877 0.401708969109739 -163.947731378667 195.692830049034 -0.837780982254625 0.402611683490436 EDNRA other 1 1 1 0.839390844977877 -0.837780982254625 3.96696826323223e-07 -87.9816218264497 67.3740185766876 -1.30586869664462 0.192285781194116 -408.253505115576 88.9901799383945 -4.58762422323676 5.86842686230853e-06 NR3C2 other 0.00246864435020942 0.0502396023682234 1 -1.30586869664462 -4.58762422323676 4.03920658296803e-06 39.8218525299402 31.3565023611024 1.26997112341647 0.204772264538682 -227.730098675768 66.7800306225836 -3.41015265420909 0.000709714706234915 AKR1C2 other 0.0233431572832513 1 1 1.26997112341647 -3.41015265420909 1.21980326860026e-23 48.276903537078 184.0624156328 0.262285504463819 0.793225498752447 -1088.88947023676 210.121145530886 -5.18219842884259 3.36320130457345e-07 DPYSL4 other 1.07171915179218e-19 0.00301275572863689 1 0.262285504463819 -5.18219842884259 0.00613521282259066 13.960523075234 11.5155202910697 1.21232238946775 0.226054667773853 32.8040494422058 13.0615014883209 2.51150677213779 0.0123872469051158 VENTX other 1 1 1 1.21232238946775 2.51150677213779 0.0106392768737476 11.139048393381 28.5152070119085 0.390635368304676 0.696260685001654 -36.5285160153797 32.348072947555 -1.12923314086135 0.259430528209763 ADAM8 other 1 1 1 0.390635368304676 -1.12923314086135 0.657729573426714 -6.66012738133576 22.0873106984411 -0.301536365031793 0.763149288260245 24.9681206896609 45.6030964584978 0.547509327845395 0.584309016998812 ITIH2 other 1 1 1 -0.301536365031793 0.547509327845395 3.06991568641588e-52 111.97288781824 8.47135310371953 13.2178279487695 8.85384283988465e-34 -42.290585265869 17.490582624447 -2.41790603400246 0.0160191408247383 KIN essential 2.94128621915505e-48 1 8.70775443302655e-30 13.2178279487695 -2.41790603400246 4.76790527675081e-05 -47.9718184595522 50.6002253529838 -0.948055431075731 0.343624002938734 -251.162137207643 66.8374588698542 -3.75780500118512 0.000194609352770869 WWC2 other 0.245880875122039 1 1 -0.948055431075731 -3.75780500118512 9.90564841657008e-17 442.783088360092 50.2933741931033 8.80400441338476 3.08886810486431e-17 495.840829627616 66.4321414698898 7.46386942610233 4.56971541995151e-13 CENPU other 8.1771127678786e-13 4.40063594941331e-09 3.00763087370638e-13 8.80400441338476 7.46386942610233 0.00212581806183176 -81.8827319325116 174.10241035332 -0.470313603162302 0.638365077663863 -639.431413150476 229.970570485736 -2.78049235517349 0.00566161879646992 ACSL1 other 1 1 1 -0.470313603162302 -2.78049235517349 1.33471441850021e-09 198.531141515213 168.086934244236 1.18112179514644 0.2381967484869 -809.809253284322 222.051650667904 -3.64694092950228 0.00029737568189271 SLC25A4 other 9.45645165507401e-06 1 1 1.18112179514644 -3.64694092950228 9.96094583302959e-19 47.362018163279 47.3145522825916 1.00100319834802 0.317379208657364 -359.140763118577 62.2932084216914 -5.76532774949377 1.5424094855298e-08 SAV1 other 8.41201875599349e-15 0.00014210218590186 1 1.00100319834802 -5.76532774949377 0.319571629965592 4.64506116959371 6.12031651174717 0.758957671662586 0.448287040506339 -1.74083749321054 7.3364243249473 -0.237286914729137 0.812545412963 CCDC122 other 1 1 1 0.758957671662586 -0.237286914729137 1.96388747270902e-09 -5.5802836686128 54.5842107699304 -0.102232561209567 0.91861897607419 -274.496865598105 65.5188566069942 -4.18958571338685 3.38271360226366e-05 SERP2 other 1.38277316953442e-05 0.278566465146412 1 -0.102232561209567 -4.18958571338685 0.602725465376009 -40.2434770586037 40.4986422909435 -0.993699412673968 0.320919124378321 -23.6225236524529 82.6501222244912 -0.285813535620556 0.775156369828419 ZNF385D other 1 1 1 -0.993699412673968 -0.285813535620556 0.0335338878695885 14.5815203780324 5.66302954064777 2.57486214284598 0.0103567521802996 16.8127758423924 7.72804061035263 2.17555479973406 0.0301250408675742 TDO2 other 1 1 1 2.57486214284598 2.17555479973406 1.86838010660108e-05 -11.3207533449656 58.2784304506825 -0.194252886658396 0.846068141172316 -355.445561637313 90.1322517536536 -3.94360015112908 9.34703243238234e-05 GUF1 other 0.100985944761788 0.746080128752758 1 -0.194252886658396 -3.94360015112908 0.760852338505248 6.96799884158426 117.90143552256 0.0591002035785302 0.952899312338482 -102.654871916386 185.955768711837 -0.552039189897159 0.581203704006147 GABRA2 other 1 1 1 0.0591002035785302 -0.552039189897159 1.43844540911421e-08 298.056220657283 221.67989171873 1.3445343118241 0.179476344168144 -784.15469483568 272.717510708378 -2.87533680106883 0.0042341139115811 SACS other 9.75409831920349e-05 1 1 1.3445343118241 -2.87533680106883 2.07897062966546e-09 9.02162975501962 5.2310409041114 1.72463376226498 0.085298976273327 -12.2692904499929 6.03220841967463 -2.03396328448723 0.0425573983243997 CCDC175 other 1.46234794090669e-05 1 1 1.72463376226498 -2.03396328448723 0.671689270354484 112.314542518373 128.030975625536 0.877245072683578 0.380835544297142 86.6438740384964 157.236015887901 0.551043433333161 0.581885510186285 PABPC3 other 1 1 1 0.877245072683578 0.551043433333161 4.7873551224002e-05 85.0108182099198 46.8856091787779 1.81315375226901 0.0704940280126414 -76.3298008566231 57.9988462731771 -1.31605722805427 0.188844750694872 CENPJ other 0.246836030110954 1 1 1.81315375226901 -1.31605722805427 0.245528390907312 12.1233547777844 17.5490276843184 0.690827719681453 0.490044833249733 -39.1076711755458 38.5618606861034 -1.01415415334559 0.311076857588942 FBXO4 other 1 1 1 0.690827719681453 -1.01415415334559 3.31912988445877e-05 29.7959039131206 13.8431920105491 2.15238681153992 0.0319214678494325 -82.4359027326913 31.5422690063263 -2.61350579174116 0.00927544221549269 TMEM267 other 0.174785379715599 1 1 2.15238681153992 -2.61350579174116 2.8455443731636e-13 -186.253796728977 400.264952454559 -0.465326268479932 0.6419290954791 -1979.4907948252 457.498828218868 -4.32676691770282 1.87617326770169e-05 GFRA1 other 2.21895550219297e-09 0.156585420922383 1 -0.465326268479932 -4.32676691770282 1.71080688248153e-26 62.6231039868389 76.0109444649323 0.823869568095291 0.410463081273636 -430.181143249388 86.1752972003833 -4.99193106638308 8.65083393966055e-07 CACUL1 other 1.52552649710878e-22 0.00764733720265993 1 0.823869568095291 -4.99193106638308 2.04358826114532e-05 602.350019995773 997.500834539542 0.603859163961326 0.546250610450278 -10495.7863511256 2568.90818343989 -4.08569929388105 5.22870684626791e-05 DST other 0.110026791980064 0.425250727806969 1 0.603859163961326 -4.08569929388105 0.000205684167086042 53.5631373430342 49.562529096091 1.08071840400208 0.280421183462391 -324.938276633798 105.341188717148 -3.08462701618349 0.00216800669378496 BEND6 other 0.976382741157439 1 1 1.08071840400208 -3.08462701618349 9.00278266364959e-49 594.492351621465 107.226840026237 5.54424947593344 5.11684630789945e-08 -444.0272792168 124.576817088087 -3.56428498974116 0.000405065276140958 TIAL1 other 8.5733499305935e-45 1 0.000470545186474433 5.54424947593344 -3.56428498974116 0.000212181495611231 -236.570348481515 361.681231599074 -0.654085221496244 0.513400956841325 -1127.59121966148 420.203529471605 -2.68344062002382 0.00756352309703775 BAG3 other 1 1 1 -0.654085221496244 -2.68344062002382 0.188630897271717 -30.4098441897737 40.6219635516879 -0.748605964137598 0.454498377194058 -136.825594893411 75.4270989239103 -1.81401110271307 0.0703632640725388 GLT1D1 other 1 1 1 -0.748605964137598 -1.81401110271307 0.091209839570107 -47.1939588186977 52.5059249298555 -0.898831110617435 0.369238741348024 -212.064292928612 97.493307745609 -2.17516768927315 0.03015422420027 TMEM132D other 1 1 1 -0.898831110617435 -2.17516768927315 0.00188995980101385 -58.2540275218442 181.354452993162 -0.321216416583058 0.748200666658442 -1407.01103190766 412.221056662934 -3.41324396016515 0.000702062822029576 SCHIP1 other 1 1 1 -0.321216416583058 -3.41324396016515 0.559455527513806 -10.1676254180612 12.2297528292016 -0.831384375470242 0.406210555743595 -17.7342414107641 16.4554427750407 -1.07771280622501 0.281756481867132 MCHR2 other 1 1 1 -0.831384375470242 -1.07771280622501 0.0243894171692027 -80.7365290914304 55.852014168079 -1.44554373363268 0.14902031674493 -177.885855546002 72.0645622748972 -2.46842345156333 0.013951846198609 TMEM56 other 1 1 1 -1.44554373363268 -2.46842345156333 0.248501649914293 -1047.76361774519 907.679893712804 -1.15433163718035 0.248997994412479 -2786.97228553499 1739.46650154937 -1.60219945773752 0.109837378310518 HSPB8 other 1 1 1 -1.15433163718035 -1.60219945773752 3.60193751596054e-07 81.5659877879114 14.7465634908239 5.5311861532123 5.53960022567483e-08 68.4889472870613 17.1981398749459 3.98234621796718 8.01440587959384e-05 POU4F1 other 0.00224580804120139 0.642514919367038 0.000509255448746287 5.5311861532123 3.98234621796718 1.67660117994738e-13 121.637347348894 38.9147425147225 3.12573948813552 0.00189411348862116 -106.388158911733 45.3842134394329 -2.3441666352489 0.0195250547619413 RNF219 other 1.31412000484275e-09 1 1 3.12573948813552 -2.3441666352489 0.720787682649559 -17.0255834493491 27.4781218372863 -0.619605064355103 0.535842974207156 -26.5025224173287 32.7438452876849 -0.809389434395368 0.418734690998634 CYSLTR2 other 1 1 1 -0.619605064355103 -0.809389434395368 0.0572309518701776 62.249469118511 103.863854868406 0.599337172661077 0.54925936421158 -197.066439253604 151.022852864644 -1.30487827183498 0.19262257791281 GRID2 other 1 1 1 0.599337172661077 -1.30487827183498 0.00181434611681073 -13.6523628726067 10.5011067141571 -1.30008800445778 0.194259241658648 12.740431375717 12.3692885446621 1.03000518823009 0.303579919258686 ARL11 other 1 1 1 -1.30008800445778 1.03000518823009 0.329793374776304 -39.3451711241714 31.6500550692484 -1.24313120587268 0.214487557055375 -75.3664791476799 53.541933498811 -1.40761594179922 0.159957359053086 RIT2 other 1 1 1 -1.24313120587268 -1.40761594179922 5.86300858281348e-05 90.1007320881931 109.538647903199 0.822547418768733 0.411215031871711 -506.812244052183 176.375293118075 -2.87348774928978 0.00425804494297839 SETBP1 other 0.299189327980972 1 1 0.822547418768733 -2.87348774928978 8.16878398045829e-26 171.170189745475 33.7380880771424 5.07349999662377 5.7907364977659e-07 -193.856820270146 42.3019516317588 -4.582692116848 6.00206296639152e-06 ARL14EP other 7.25959832343328e-22 0.0513476486774794 0.00522440246828439 5.07349999662377 -4.582692116848 1.71861933406942e-08 14.3500699916663 50.7923290409786 0.282524354811311 0.777675545657435 -364.910824206159 81.0372535922357 -4.50300087959942 8.61175698593321e-06 EPG5 other 0.000116092736016389 0.0731568755955026 1 0.282524354811311 -4.50300087959942 0.816987447560426 -3.77404167243897 13.0591719302124 -0.28899548092385 0.772722193185063 5.21065734271528 20.8354184065751 0.250086522911915 0.802638230815254 PSTPIP2 other 1 1 1 -0.28899548092385 0.250086522911915 4.3603922902588e-15 1214.39457724826 537.09287207331 2.26105137564086 0.0242481776585181 -4118.67569976159 856.911508067921 -4.80641893705918 2.11819363681483e-06 ATP5A1 essential 3.51142391134541e-11 0.0184685303193885 1 2.26105137564086 -4.80641893705918 6.33044595715406e-09 110.454108417816 23.745365670187 4.65160696836498 4.37394216536267e-06 -9.93388940696243 37.8848392225299 -0.262212790414979 0.793281233930984 HAUS1 essential 4.36484248745773e-05 1 0.0385125607660183 4.65160696836498 -0.262212790414979 3.42257101194149e-07 13.6313276332952 43.5399771059215 0.313076132312465 0.754372526001198 -277.159511562713 68.8640656553053 -4.02473349380818 6.72514045523546e-05 C18orf25 other 0.00213705333985627 0.542046320691978 1 0.313076132312465 -4.02473349380818 0.172941004311126 26.31837823822 34.3379238242679 0.76645222853048 0.443820148365974 -30.1618819979727 42.6035720507285 -0.707966035384512 0.479342909703196 PDE3B other 1 1 1 0.76645222853048 -0.707966035384512 0.194896988932658 -5.9734042147203 16.8267657519573 -0.354994198099268 0.722765593461511 13.6385163757375 19.5630441903882 0.697157162403101 0.486075999184507 KCNK13 other 1 1 1 -0.354994198099268 0.697157162403101 4.64992658384242e-64 44.8743772542497 9.16066722275388 4.89859266394785 1.36071634157543e-06 -53.2900350914681 11.4881730711016 -4.63868665292993 4.63690635558592e-06 ZNF547 other 4.51786866886129e-60 0.0398820315643945 0.0121552790792933 4.89859266394785 -4.63868665292993 3.72037446644923e-56 97.8451295779203 14.6425011462369 6.68226886928169 7.18637515709034e-11 -36.2784806036967 18.365500885866 -1.97536025993261 0.0488560826248505 ZNF773 other 3.58532487331713e-52 1 6.84430369961284e-07 6.68226886928169 -1.97536025993261 1.37420648003415e-59 177.784442572635 34.3079546817373 5.18201811276357 3.35993574700192e-07 -167.851611935477 43.0310891429655 -3.9007056358209 0.000111010904333936 ZNF776 other 1.32940734878504e-55 0.878651307803101 0.00304645374180664 5.18201811276357 -3.9007056358209 3.00176973156039e-46 42.6542307400953 8.39920365462946 5.07836605635645 5.64756446428319e-07 -27.8693269334511 10.4791573277001 -2.65950076537001 0.00811325271442588 ZNF256 other 2.8453775285461e-42 1 0.00509749168546201 5.07836605635645 -2.65950076537001 1.67037529512351e-25 106.83116746512 10.3410484000572 10.3307869117535 1.55210749982128e-22 37.5653473835863 21.1031215371784 1.78008487120759 0.0757552321038818 SUV39H2 other 1.48212399936309e-21 1 1.52091013907487e-18 10.3307869117535 1.78008487120759 2.56278728301001e-24 66.9031378025216 6.18133597082941 10.8234106863382 2.35934683584178e-24 50.5097624975555 12.7692009277666 3.95559305419982 8.90266146029605e-05 DCLRE1C other 2.25960954742993e-20 0.711767783750669 2.31499111532795e-20 10.8234106863382 3.95559305419982 4.03270320090304e-44 90.4461265293674 6.72629192407576 13.446654940091 9.4874387756238e-35 5.60328141852746 13.8949530461798 0.40326019094163 0.686953601174722 RPP38 other 3.80364565909175e-40 1 9.33279352358114e-31 13.446654940091 0.40326019094163 1.37398350858166e-39 146.832632036475 16.5320802255145 8.88167913738181 1.71214641988794e-17 -169.820142273353 34.1514286150711 -4.9725633497631 9.50271082000474e-07 NMT2 other 1.28192661350669e-35 0.00838614229865419 1.66814425689682e-13 8.88167913738181 -4.9725633497631 1.18516899332929e-08 -31.8647108562183 11.8569606249008 -2.68742655595053 0.00747532053203807 -73.0993345832867 14.8011373008844 -4.93876471093333 1.12116494156458e-06 ZSCAN1 other 8.06507499960582e-05 0.00986625148576827 1 -2.68742655595053 -4.93876471093333 1.34529683624503e-25 27.3596134141954 6.01870838394633 4.54576159349597 7.09977785777149e-06 -5.96220680678993 7.51421052446527 -0.793457514582241 0.427942904193719 ZNF837 other 1.19435453121834e-21 1 0.0620378589212073 4.54576159349597 -0.793457514582241 5.67641356814297e-10 41.2906336088145 59.1579114943216 0.69797314620848 0.485568627670748 -274.451790633608 72.3624980751869 -3.79273515887255 0.00017016870954218 USP12 other 4.08304427956524e-06 1 1 0.69797314620848 -3.79273515887255 1.45881288568838e-05 503.353877906759 178.582254628564 2.81861083540295 0.00504428681760179 -688.96876248351 344.550310204203 -1.99961730429203 0.0461659002700283 CCDC50 other 0.0798116529760114 1 1 2.81861083540295 -1.99961730429203 1.40380665441694e-14 118.878507520901 49.1414221973668 2.4191100339638 0.0159697755618151 -199.242838684514 60.1102368110178 -3.31462408492781 0.000994829006695895 PAN3 other 1.12079923288648e-10 1 1 2.4191100339638 -3.31462408492781 1.59630152803317e-13 -352.396929466791 354.96959779717 -0.992752426274407 0.321378733859379 -3722.75069615162 541.994075402749 -6.86861880064886 2.23261691699028e-11 PFKM other 1.25229854874203e-09 2.12522804328305e-07 1 -0.992752426274407 -6.86861880064886 0.0720090712353966 -24.8994534876899 16.8234013036019 -1.48004871537832 0.139580790600438 -80.7727919139692 36.742863060506 -2.19832601996631 0.0284494869206667 IGSF10 other 1 1 1 -1.48004871537832 -2.19832601996631 0.899887464396147 -11.6844416562108 32.265423297352 -0.362135080284837 0.717425743907443 -29.3471636059466 69.250116082663 -0.423785045658484 0.671930622678355 SPEF2 other 1 1 1 -0.362135080284837 -0.423785045658484 4.63675158690444e-05 -16032.3867862295 10099.2973018895 -1.58747547546996 0.113126594917757 -62142.9172073455 14785.5633408763 -4.20294552021192 3.19499239934974e-05 SPARCL1 other 0.239580954495352 0.263522973098367 1 -1.58747547546996 -4.20294552021192 0.477712358519515 -15.8812251063183 24.9379899557355 -0.636828595027395 0.524569184129399 12.0382474847823 36.254889935511 0.332044794679987 0.740014270420531 MEPE other 1 1 1 -0.636828595027395 0.332044794679987 0.000692623015027092 232.67777620697 130.941340266624 1.77696192610515 0.0762716248291435 -701.371221224761 285.985095160928 -2.45247473764354 0.0145786595488293 MBNL1 other 1 1 1 1.77696192610515 -2.45247473764354 0.814209441801476 -8.2271016311167 20.4940716257492 -0.401438122270442 0.688293371245643 -27.8273259571881 43.9856878990959 -0.632645009918331 0.527295615261108 CAPSL other 1 1 1 -0.401438122270442 -0.632645009918331 0.168555061098367 158.257214554582 201.392334727284 0.785815481849821 0.432400485508598 -481.74416372001 432.241115496772 -1.11452646786353 0.265664574796213 NADK2 other 1 1 1 0.785815481849821 -1.11452646786353 0.00281287256541049 -295.433963330759 152.593614522974 -1.93608339545741 0.0535034928225585 -974.963999698509 283.599148889443 -3.43782413845884 0.000642732310497069 GPD1L other 1 1 1 -1.93608339545741 -3.43782413845884 0.736912658712104 -2703.92084922756 3655.2994936389 -0.73972621229342 0.459864238215179 -1983.73976511579 4738.30734259334 -0.418660002757454 0.675670784029221 GJA1 other 1 1 1 -0.73972621229342 -0.418660002757454 3.86439446512587e-11 159.536213241303 29.3966493087424 5.42702032349851 9.52637641895558e-08 11.6818152744475 38.9185229451319 0.300160807513604 0.764197557303908 GPR180 other 2.87510948205365e-07 1 0.000871853969862815 5.42702032349851 0.300160807513604 0.000720514662342691 266.338083494804 87.0097003631465 3.06101598308242 0.00234187536741857 150.340736304386 111.781478085432 1.34495212336953 0.179338270722469 TCTEX1D1 other 1 1 1 3.06101598308242 1.34495212336953 1.62920076703483e-09 130.371437378897 44.0681922415274 2.95840221138099 0.00326028950658495 -34.655552228289 56.6144653383652 -0.612132465107012 0.540768477363588 WDR78 other 1.14956406121978e-05 1 1 2.95840221138099 -0.612132465107012 3.07008932743722e-05 125.804780876493 35.9556927177563 3.49888352489912 0.000515020597667227 199.06374501992 43.417805585095 4.58484122671222 5.93641050636124e-06 ANKRD22 other 0.162315622741606 0.0508097375239459 1 3.49888352489912 4.58484122671222 3.45673370780128e-08 756.509423316251 352.878810518139 2.14382218701501 0.0325983531758676 -1234.68569476228 467.123766169703 -2.64316608184248 0.00850867501348791 FARP1 other 0.000229008608141835 1 1 2.14382218701501 -2.64316608184248 1.48469690796215e-16 -48.447720903042 76.5647383146275 -0.632768059677234 0.527216075954268 -513.923875353195 92.5932701324586 -5.55033723960721 4.95315985959248e-08 IFIT5 other 1.22205402494364e-12 0.000452619747969561 1 -0.632768059677234 -5.55033723960721 1.88535263079033e-09 10.2565896937727 45.3525082370473 0.226152644968693 0.821188437438344 -191.051743209703 54.8468804153831 -3.48336572222106 0.00054507324065062 PANK1 other 1.32804239312871e-05 1 1 0.226152644968693 -3.48336572222106 0.50563605283117 -69.0590258251531 66.1564305914876 -1.04387472552123 0.297121775186323 -102.348882856775 92.7383327240024 -1.10363082719391 0.270362051124994 PRDM8 other 1 1 1 -1.04387472552123 -1.10363082719391 3.24787519026484e-07 601.007343970561 400.136497196262 1.50200581097149 0.133817831559428 -1773.54808984999 590.188237943183 -3.00505495675555 0.00280814184216642 HNRNPDL other 0.00203154593151066 1 1 1.50200581097149 -3.00505495675555 0.0213859386521639 -1.60205826816852 19.0281913139396 -0.0841939331876953 0.932940708850629 34.447919770757 22.977232495277 1.49921970706602 0.134537038959922 HHEX other 1 1 1 -0.0841939331876953 1.49921970706602 0.00225182701489891 -323.758263484981 261.065346403408 -1.24014262308371 0.215588110690393 -984.344259902249 331.464636926866 -2.96968107677632 0.00314525729435234 UTRN other 1 1 1 -1.24014262308371 -2.96968107677632 0.00733214130860465 -39.8149662969087 46.7986013840325 -0.850772568397598 0.395362687429582 -149.922088574844 59.6092578061853 -2.51508061151011 0.0122591885665145 GRM1 other 1 1 1 -0.850772568397598 -2.51508061151011 3.28232993668849e-06 -216.464955138185 158.886449638851 -1.36238776579256 0.173777282240444 -839.220523986136 204.414980832514 -4.10547466026351 4.81611946947731e-05 PTPRK other 0.019103160231527 0.392417414373011 1 -1.36238776579256 -4.10547466026351 3.67158100133598e-09 146.085920183815 32.2563371397119 4.52890604258855 7.65386413109984e-06 -205.599483983768 70.0750102553518 -2.93399149332363 0.00352212380646087 GGPS1 essential 2.5528502702289e-05 1 0.0667570029514528 4.52890604258855 -2.93399149332363 0.0879717312185197 -221.229401914906 155.936859482187 -1.41871141082059 0.156695956242 -751.373974925942 359.903761449337 -2.08770803589312 0.0374027638679872 CNTNAP4 other 1 1 1 -1.41871141082059 -2.08770803589312 0.62462779100519 -42.5600905168367 130.9754435335 -0.324947099766462 0.745376258144414 204.95480020636 286.049816558972 0.716500372808687 0.474064293110674 PLOD2 other 1 1 1 -0.324947099766462 0.716500372808687 0.723298013863114 -17.5668758840163 78.6596065550147 -0.223327787327922 0.823384520521753 -96.0872524752473 126.070367591513 -0.762171589652095 0.44636782461162 STK32B other 1 1 1 -0.223327787327922 -0.762171589652095 0.000357232398657758 -329.674701326569 165.591424005523 -1.99089236237 0.0471135976092432 -1312.03688016183 326.597233992946 -4.01729330074535 6.9280356975313e-05 NRSN1 other 1 0.557914714722195 1 -1.99089236237 -4.01729330074535 0.910907397331252 -11.2284730812674 84.56105792505 -0.132785390306016 0.894424089586703 -55.4106384123049 134.310521511126 -0.41255620028037 0.680133656107161 JAKMIP1 other 1 1 1 -0.132785390306016 -0.41255620028037 0.0206234293446313 236.243314863886 127.1318454576 1.85825442880617 0.0638051184138967 709.681281618882 265.356882246528 2.67444083458728 0.00776612706464117 ZIC1 other 1 1 1 1.85825442880617 2.67444083458728 0.00399010337587706 189.991155138865 173.362776026543 1.09591666385047 0.273720216543348 -570.864670521163 282.240235789023 -2.02261973359422 0.0437223072117575 ADGRA3 other 1 1 1 1.09591666385047 -2.02261973359422 0.57610735207843 -4.95049385690158 9.50491935220313 -0.520834914370326 0.602745578067747 -20.761382799325 19.8392130329493 -1.04648217471349 0.295916941192251 CPB1 other 1 1 1 -0.520834914370326 -1.04648217471349 0.483064102430214 135.846983902352 121.630057204404 1.11688662346065 0.264657908494643 198.172778931232 198.01768759833 1.00078321959408 0.317486718337938 LGI2 other 1 1 1 1.11688662346065 1.00078321959408 2.33228913841684e-08 232.735210304341 60.3396698098107 3.85708458528059 0.000132057205014375 -209.182404054398 104.113747998358 -2.00917177679261 0.0451347768717048 CDYL other 0.000156193403599776 1 1 3.85708458528059 -2.00917177679261 0.342246946309434 8.27972912635827 11.1915477650181 0.739819844422108 0.459806562445257 -6.86096190360207 15.7708691248117 -0.435040190195224 0.663748019550054 BANK1 other 1 1 1 0.739819844422108 -0.435040190195224 0.916269351014521 -61.6412334801768 149.554103793591 -0.412166780560243 0.680420219593017 -84.3336417033764 318.140449976858 -0.265083052813658 0.791071049245347 DAB2 other 1 1 1 -0.412166780560243 -0.265083052813658 9.42485187276761e-07 33.8871740464346 142.066310231615 0.23853068325057 0.811581077582328 -723.100447159811 192.362958499974 -3.75904203594326 0.000193679875921163 SCOC other 0.00572277005714449 1 1 0.23853068325057 -3.75904203594326 0.284660125547825 54.8475066974199 36.0708076709968 1.52055111151616 0.129094062504558 34.1519395494477 48.841187384709 0.699244661691822 0.484770296467263 CLGN other 1 1 1 1.52055111151616 0.699244661691822 1.38366201410506e-12 249.016262007412 202.086531170876 1.23222592106771 0.218527272160426 -1209.24676650783 274.495705647374 -4.40533947026939 1.33012906466284e-05 SMARCA5 other 1.06223732822846e-08 0.111890456919438 1 1.23222592106771 -4.40533947026939 0.00506367943521929 5.05496858937752 6.03685480126767 0.837351361890638 0.402854898221595 -23.4341328764516 10.4507647079216 -2.24233666448242 0.0254427108254392 SYCP2L other 1 1 1 0.837351361890638 -2.24233666448242 0.32420845228041 -23.3454741316563 22.8927741087513 -1.01977479971429 0.308400790623847 -60.1887646664923 40.9098302020363 -1.47125432614229 0.141943709000493 BMP6 other 1 1 1 -1.01977479971429 -1.47125432614229 0.893967845376263 -13.0113152451636 34.1472617235434 -0.381035391666346 0.703362582988845 1.16733584783228 55.58329368497 0.0210015594694406 0.983254019296903 RASSF3 other 1 1 1 -0.381035391666346 0.0210015594694406 0.000328936745331976 1398.73676483173 465.686842573577 3.00359949424754 0.00282168885056646 -1525.96407870618 946.11644865765 -1.61287131290363 0.107496004090376 HNRNPU essential 1 1 1 3.00359949424754 -1.61287131290363 0.323490617417102 116.077849930246 87.8771988344516 1.32090976350897 0.187224305174106 -38.9413821165223 173.655214408043 -0.224245394814467 0.822671407866662 AHCTF1 essential 1 1 1 1.32090976350897 -0.224245394814467 0.305528930318235 -10.2788348426869 32.3043118230815 -0.318187705064891 0.75049455924264 -75.1936513864274 52.5804486010987 -1.43006865454655 0.15341187800445 PTPRR other 1 1 1 -0.318187705064891 -1.43006865454655 0.434158285470476 0.00474212588439212 20.5713385300159 0.000230521017262577 0.999816175793369 -37.790841979586 34.8761933390376 -1.08357129495799 0.279151038997418 FEZF2 other 1 1 1 0.000230521017262577 -1.08357129495799 0.000226056008394631 -29.9626447297141 58.1117586391247 -0.515603819801476 0.606391884385859 -536.007187083742 134.455438433306 -3.98650432685636 7.85752932265815e-05 SLC25A27 other 1 0.63025242697041 1 -0.515603819801476 -3.98650432685636 2.18082458663958e-16 262.1264958199 36.9152072009832 7.10077270846033 5.0586188117659e-12 -139.429036664664 87.2339446668301 -1.59833465283705 0.110691275310984 TRAPPC8 essential 1.79002082071376e-12 1 4.85475647365173e-08 7.10077270846033 -1.59833465283705 1.42643278721525e-06 50.722813318877 15.6410903907814 3.24292054144589 0.00127378977164549 -70.858261046353 33.9078589720946 -2.08972973211513 0.0372197053491384 INO80C other 0.00853434736590885 1 1 3.24292054144589 -2.08972973211513 0.000771342768072536 -134.021894767078 427.919889921268 -0.313193889612695 0.754283815355704 -2079.03153467193 652.56487627783 -3.1859384564651 0.00154698365759378 LPCAT1 other 1 1 1 -0.313193889612695 -3.1859384564651 0.717512526855707 2.26674538085986 25.8343333679343 0.08774158591889 0.930122817460753 -23.2714363212815 39.7344108723014 -0.58567462837366 0.558400725994726 PLEKHG4B other 1 1 1 0.08774158591889 -0.58567462837366 7.38239186543509e-22 76.4082743603702 18.8025761457147 4.06371306613665 5.72464851701576e-05 -47.0956701315979 22.1888418485521 -2.12249338893147 0.0343568055383711 TMEM251 other 6.41603677024963e-18 1 0.481614679736536 4.06371306613665 -2.12249338893147 1.20094982407723e-09 88.5566545489602 34.5886927692716 2.56027757798449 0.0107940416866787 -140.081503880778 47.3492949179883 -2.95847074646851 0.00325957905813763 ING1 other 8.52794470077239e-06 1 1 2.56027757798449 -2.95847074646851 0.088443067868787 5.04082023763897 3.27079150596663 1.54116220139481 0.124002752236438 -0.85722499041776 4.52790972808904 -0.189320247508455 0.849929926488282 TEX29 other 1 1 1 1.54116220139481 -0.189320247508455 0.0233759621353303 0.699047237744033 14.8775634645956 0.0469866748952251 0.962545763725558 -44.5019583268056 21.180166397332 -2.10111466982674 0.0362151143980367 ADPRHL1 other 1 1 1 0.0469866748952251 -2.10111466982674 0.353483112782921 34.4394844447794 34.2438777855755 1.0057121643883 0.315111868299209 88.7811057302758 63.6431257298856 1.39498342848654 0.163731046730461 CMTM7 other 1 1 1 1.0057121643883 1.39498342848654 0.325851880619949 23.8746349263683 44.4458296707091 0.537162543780845 0.591429361581534 -75.791431176738 80.7783195386962 -0.938264519608268 0.348627950490953 FBXL2 other 1 1 1 0.537162543780845 -0.938264519608268 3.31746967718995e-05 40.7763447003034 76.9538703063597 0.529880362585657 0.596463986914747 -514.070768149052 139.855100114858 -3.67573844448191 0.000266652221325659 UBP1 other 0.174731127897595 1 1 0.529880362585657 -3.67573844448191 2.61836561675676e-07 281.959094498078 253.951995148748 1.11028501403553 0.267490997875385 -937.764648458536 292.979928087737 -3.20078120907215 0.00147122332768751 PTPRD other 0.00164746086608737 1 1 1.11028501403553 -3.20078120907215 0.00253455215130867 5.08316517959341 10.8507889018727 0.468460424911234 0.63968894443903 -26.0719435682023 12.2565770986692 -2.12717982829261 0.0339646044442822 LURAP1L other 1 1 1 0.468460424911234 -2.12717982829261 1.16499758479618e-07 245.316742726755 52.4883230264548 4.67373938777035 3.94295464253325e-06 102.169471382391 69.1935203674899 1.4765757088202 0.140507988964217 CNKSR3 other 0.000746646952095872 1 0.0347729169925007 4.67373938777035 1.4765757088202 0.00401920408649037 21.4893850343711 14.2878403722733 1.50403311308496 0.133293541659063 -56.384862175377 28.3785558613146 -1.98688271703918 0.047557961351637 GTF2E1 essential 1 1 1 1.50403311308496 -1.98688271703918 3.78339096903393e-08 450.796849736049 88.5178082358619 5.09272494111997 5.25365558830014e-07 -225.072381829406 204.296509268506 -1.10169470166323 0.271199444318147 CFDP1 essential 0.000249968641324072 1 0.00474247489955853 5.09272494111997 -1.10169470166323 0.00395101292858096 91.449838999156 38.5342324903425 2.37321034023644 0.0180648861919779 -112.754843222128 86.288963895029 -1.30671221593639 0.191996139427954 ZDHHC7 other 1 1 1 2.37321034023644 -1.30671221593639 0.787595082073472 -5.67337695017752 138.16422347793 -0.0410625616919113 0.967264731687728 -210.470894145273 318.878981810343 -0.66003376249631 0.509579091491396 CMIP other 1 1 1 -0.0410625616919113 -0.66003376249631 0.0127591286051745 -376.856630138301 147.320977641246 -2.55806495566448 0.0108611497652732 -765.231524041481 288.899307151084 -2.64878282882586 0.00837012516006573 SPHKAP other 1 1 1 -2.55806495566448 -2.64878282882586 0.0106609549493561 -410.638615051693 349.127749202976 -1.17618440811176 0.240160059869684 -1968.62900880476 662.256408777137 -2.97260846813073 0.00311563628099328 PID1 other 1 1 1 -1.17618440811176 -2.97260846813073 1.00780191027886e-05 304.255497027982 167.926753142397 1.81183457271982 0.0706964838144766 -818.887636861022 309.368697592506 -2.64696345568757 0.00841456300936407 TRIP12 other 0.0560136301732989 1 1 1.81183457271982 -2.64696345568757 1.94302398830456e-06 -6.39950707968923 21.240058421658 -0.301294231524514 0.76333312334961 -173.150153696167 39.1302105693967 -4.42497372686221 1.21881692094917e-05 FBXO36 other 0.0115124171307045 0.102770642774434 1 -0.301294231524514 -4.42497372686221 1.26251741054523e-41 640.221136607944 90.9822844782912 7.03676699567489 7.629457085901e-12 -111.678897452942 116.935817863136 -0.955044395239556 0.340082039646021 CEBPG other 1.18373632412721e-37 1 7.31436050825328e-08 7.03676699567489 -0.955044395239556 8.3304215197421e-23 280.238271385722 91.078420289827 3.07688989877027 0.00222351906184357 -351.652950759305 120.2448896186 -2.92447314704765 0.00363031969548412 KCTD15 other 7.28412057686249e-19 1 1 3.07688989877027 -2.92447314704765 1.10034684651666e-53 56.1670958846323 8.6856838436287 6.46662909862107 2.69204255913479e-10 -41.7208740554126 11.4671410825496 -3.63829778975184 0.000307305204387878 ZNF599 other 1.0572132501332e-49 1 2.55259475457161e-06 6.46662909862107 -3.63829778975184 0.00808436455460136 1.85354314938174 5.37517828412105 0.344833799254127 0.73038484281945 -9.55257487387204 6.93546823627542 -1.37735111003869 0.169107147258303 MCOLN2 other 1 1 1 0.344833799254127 -1.37735111003869 8.38846681682887e-05 358.023349668949 170.379445070123 2.10132947387872 0.0361854258620497 -66.2885325876501 224.978061398255 -0.294644429664217 0.768405755016174 LGI4 other 0.419339456173275 1 1 2.10132947387872 -0.294644429664217 4.30943068800968e-31 -308.110358890413 406.235596082953 -0.758452390340252 0.448588119404866 -3946.3950937024 524.156395221492 -7.52904119777987 2.94182092456276e-13 DDAH1 other 3.9151177800568e-27 2.83503282500114e-09 1 -0.758452390340252 -7.52904119777987 5.92660048105359e-35 223.943548052917 129.505050666696 1.72922636530427 0.0844731711510766 -984.167858881784 167.097372005212 -5.88978657815807 7.7116001723504e-09 HS2ST1 other 5.45662106290604e-31 7.13477247945859e-05 1 1.72922636530427 -5.88978657815807 3.79839484878601e-24 2.19461726669134 14.8207337410278 0.148077504463631 0.882349902390926 -130.793948169969 19.2101740113285 -6.80857695993999 3.26845951510244e-11 ZUFSP other 3.34524634332584e-20 3.10503653934732e-07 1 0.148077504463631 -6.80857695993999 6.30436516704014e-17 63.8595945473658 51.4709460560129 1.24069206883959 0.215385188451557 -308.613941179403 66.7150390487441 -4.62585266500286 4.92224131337352e-06 NUS1 essential 5.21749261224242e-13 0.0422771306405652 1 1.24069206883959 -4.62585266500286 1.73442216112616e-25 70.1301019387224 84.9108891693848 0.825925892718225 0.409295777429575 -504.659474355234 96.635583583976 -5.22229447620282 2.73696707664976e-07 PPP2R5E other 1.5384324569189e-21 0.00245752273812382 1 0.825925892718225 -5.22229447620282 0.0756164409427852 20.687832743531 15.8641110722628 1.30406504652518 0.192896302708525 -22.9821178450346 11.9719358833159 -1.91966596455486 0.0555493869401281 SLC5A10 other 1 1 1 1.30406504652518 -1.91966596455486 0.000668102733280682 -198.822228636499 328.415955391856 -0.605397592206718 0.545228397101074 645.194862688613 421.742762402355 1.52983031413134 0.126780602725225 AK5 other 1 1 1 -0.605397592206718 1.52983031413134 0.59823769624726 1.32649617253953 13.536831269975 0.0979916308391707 0.921984599265839 -17.2086654977403 22.9214797907914 -0.750765904069325 0.453204189787303 CABYR other 1 1 1 0.0979916308391707 -0.750765904069325 8.46700955694987e-05 297.850629497664 109.016010226286 2.73217327325969 0.00655038355670453 -194.649620990436 182.45053119523 -1.06686245151105 0.286631181214603 IMPACT other 0.422927127369646 1 1 2.73217327325969 -1.06686245151105 0.666097071471377 10.8948443526917 19.1657776627761 0.568453028329327 0.57002762128689 -6.39310859998956 31.4443104909718 -0.203315273897487 0.838985925042486 ANKRD29 other 1 1 1 0.568453028329327 -0.203315273897487 1.77828354976112e-07 -8.55010547686643 19.3441620897288 -0.441999267645006 0.658709897511425 -120.080289307977 27.5394304549505 -4.36030401951871 1.62388165012131e-05 SDHAF4 other 0.00113027702422817 0.135967610564658 1 -0.441999267645006 -4.36030401951871 0.00179864861272784 173.642823529415 229.802764105828 0.755616775129171 0.450289836901999 -963.796352941171 400.83126666573 -2.40449394319561 0.0166138711515378 CHST9 other 1 1 1 0.755616775129171 -2.40449394319561 0.433118149803563 51.1175084860103 50.9159886262613 1.00395788955859 0.315953220714397 -48.2293739091321 117.512610734592 -0.410418708321103 0.681699512700581 DNAAF1 other 1 1 1 1.00395788955859 -0.410418708321103 0.756843745719792 -1.51576925595299 5.23825937669242 -0.289365063268419 0.772438945009869 5.88649565507498 11.330256694189 0.519537713394793 0.603648260915242 C16orf74 other 1 1 1 -0.289365063268419 0.519537713394793 0.205419356050309 -144.229373902868 210.15748162112 -0.68629188354517 0.492892198875561 -795.67885703141 446.547163660753 -1.78184729807375 0.0754668541152322 JPH3 other 1 1 1 -0.68629188354517 -1.78184729807375 0.00203153320878895 -3.26531332390543 186.192293268165 -0.0175373172895107 0.986015984820848 -893.588193442336 312.847158793683 -2.85630912196215 0.00449083686978894 ANKH other 1 1 1 -0.0175373172895107 -2.85630912196215 0.000274727910079449 25.2227736832593 21.1861264871592 1.19053257321704 0.234484921905555 -86.4352681965404 35.5977111673752 -2.42811308261182 0.0155812793408574 OTULIN other 1 1 1 1.19053257321704 -2.42811308261182 0.0432653730231616 179.115218841861 116.558216291542 1.5367017833719 0.125093374493809 -140.765865358606 198.52548693637 -0.709056895066191 0.478669007807553 RETREG1 other 1 1 1 1.5367017833719 -0.709056895066191 0.823498168860668 -4.83505154639181 7.99591082357196 -0.604690529081199 0.545702843951479 -7.05992268041251 15.5012918685721 -0.45544092326434 0.649021412066672 CDH12 other 1 1 1 -0.604690529081199 -0.45544092326434 0.000104281622376478 77.025703586979 114.432530139725 0.673110202954777 0.501233798882064 -767.156026025522 221.575294640285 -3.46228142117991 0.000588489669652765 TOMM70 other 0.515881185896438 1 1 0.673110202954777 -3.46228142117991 0.549975562726762 113.356268056218 208.348400201196 0.544070738948574 0.586669637376848 -252.92897148225 417.762642419145 -0.605437025239046 0.545202226542481 ABI3BP other 1 1 1 0.544070738948574 -0.605437025239046 3.2284135495038e-50 97.1808033520974 42.3974792036482 2.29213635285504 0.0223723663929622 -393.931231488368 54.4625529757335 -7.23306584000735 2.1314973319726e-12 CC2D1B other 3.08281209842118e-46 2.04517169002771e-08 1 2.29213635285504 -7.23306584000735 0.0510500956917081 -40.8358445141767 45.6262439380372 -0.89500780668323 0.371275607474606 -207.028605821253 86.1517326600147 -2.40306955448315 0.01667398947123 LRRK1 other 1 1 1 -0.89500780668323 -2.40306955448315 0.0412984270187984 -0.21567818463109 3.24838517056596 -0.0663955083237596 0.947093310602665 -6.68809836373 4.16459250047659 -1.60594304555959 0.109008752870607 ENPP3 other 1 1 1 -0.0663955083237596 -1.60594304555959 0.564621055383922 -10.9916724938017 14.8693195949486 -0.739218255658169 0.460171348876334 -25.4517397610967 24.1207231819056 -1.0551814541029 0.29192535814085 C4orf19 other 1 1 1 -0.739218255658169 -1.0551814541029 0.137365036184077 969.033762349293 845.178778146831 1.14654294145202 0.252197961220782 -1018.5845191698 1388.73244845192 -0.733463469011083 0.463669088839772 UCHL1 other 1 1 1 1.14654294145202 -0.733463469011083 0.0042641279063092 239.980623382468 100.599335204732 2.3855090383458 0.0174796850576393 -398.831641723865 237.982557509982 -1.67588602247514 0.0944741494537246 MIA3 other 1 1 1 2.3855090383458 -1.67588602247514 0.177120765148308 47.5688758861255 37.2582941555007 1.27673252263221 0.2023731611238 -89.2591875773601 88.1399873422638 -1.01269798497645 0.311763532795429 DISP1 other 1 1 1 1.27673252263221 -1.01269798497645 0.0598723597305899 129.075927043944 54.24934299433 2.37930857627962 0.0177765554970056 104.674599896201 120.014393456496 0.872183717981666 0.383590412374247 PGM5 other 1 1 1 2.37930857627962 0.872183717981666 0.000189517206792598 98.5188418928405 47.5483332624625 2.07197256208804 0.0388540206827032 -309.011107450269 125.237669165857 -2.46739746522299 0.0139922048702789 LONRF1 other 0.905892248468619 1 1 2.07197256208804 -2.46739746522299 5.67328912201768e-05 109.42392505384 69.6828820211567 1.57031284987061 0.117067748186911 -163.138289590186 94.4004136435489 -1.72815227490621 0.0846689545827227 SH3RF1 other 0.290075272808764 1 1 1.57031284987061 -1.72815227490621 0.00273574586450984 -22.7470043544771 45.8261000652356 -0.49637661337307 0.619877731001311 -133.576673849309 59.1283571623507 -2.25909665446215 0.0243682457634235 GBP5 other 1 1 1 -0.49637661337307 -2.25909665446215 1.62944340415431e-25 417.695926187883 120.568371376048 3.46439054804104 0.000583770787086249 -370.693529827819 139.966858574472 -2.64843787738928 0.008378534316871 BUB3 essential 1.44596807684653e-21 1 1 3.46439054804104 -2.64843787738928 0.00237503286998977 -38.4014561530663 37.879464821977 -1.01378032486844 0.311248547023306 -114.249063582294 43.9807081597787 -2.59770859457823 0.00970166307966666 GPR26 other 1 1 1 -1.01378032486844 -2.59770859457823 0.706868110498564 -19.418132858381 38.5874148383161 -0.50322450829485 0.615059977107226 -3.95121687246011 44.802687646729 -0.0881915143934134 0.929764861075257 C10orf90 other 1 1 1 -0.50322450829485 -0.0881915143934134 4.32893281749576e-25 -158.986728391469 100.784260060179 -1.57749561584851 0.115403456986399 -955.098811814732 130.032425404459 -7.34508188126116 1.01236889051986e-12 FAM69A other 3.83500158301949e-21 9.73190214456738e-09 1 -1.57749561584851 -7.34508188126116 3.80527850895102e-13 33.0669324124758 24.2867791495148 1.36151987091036 0.174049398019466 -152.088240192758 34.3210106647561 -4.43134503463023 1.18485208212903e-05 SRSF12 other 2.95822351285852e-09 0.0999896672108689 1 1.36151987091036 -4.43134503463023 1.53130449495403e-07 611.205227690429 144.486938387089 4.23017633644485 2.84639938776227e-05 68.540330814788 190.874819111082 0.359085243061318 0.719704753224756 PDLIM3 other 0.000976359745982687 1 0.242655547806733 4.23017633644485 0.359085243061318 0.0777142458348393 161.608740044923 109.654189815586 1.47380360309727 0.141254438490195 -21.2378844190356 144.858932436847 -0.146610803087994 0.883506835549312 SORBS2 other 1 1 1 1.47380360309727 -0.146610803087994 0.611013604443172 115.680028853176 127.357888034708 0.908306745960254 0.364307405987151 -4.02653964232542 225.990068342934 -0.0178173300793699 0.985794183339365 CXADR other 1 1 1 0.908306745960254 -0.0178173300793699 0.000761357084848102 275.859384758841 74.9762927207756 3.67928814226903 0.000268610715433136 61.0842020074073 133.041602507182 0.459136096200507 0.646406051226936 BTG3 other 1 1 1 3.67928814226903 0.459136096200507 0.710618504362933 -59.4461951055993 78.8353520960293 -0.754055046690068 0.451297077272152 2.81168728055389 139.892860488235 0.0200988618771602 0.983975371438382 C21orf91 other 1 1 1 -0.754055046690068 0.0200988618771602 0.997353367251995 4.98441166610831 75.0687551778636 0.0663979528406796 0.947096959487925 7.0998112108971 133.209056798914 0.0532982620064236 0.957523107521785 CHODL other 1 1 1 0.0663979528406796 0.0532982620064236 0.0799229261245169 9.91267180690625 320.267753750849 0.0309512015830909 0.975325190176822 -1174.42103498774 568.313212323494 -2.06650313510437 0.0394782252899854 NCAM2 other 1 1 1 0.0309512015830909 -2.06650313510437 0.000580444777870525 -35.5931424268752 20.3283009171151 -1.75091575887231 0.0806604566716678 -127.874384728722 33.5717680749432 -3.80898570618219 0.000159464807383078 L3MBTL4 other 1 1 1 -1.75091575887231 -3.80898570618219 0.000131860165768521 48.9923568622081 19.746112102745 2.48111408500499 0.0135396125702028 -80.1117931074935 36.6972138415484 -2.18304837673511 0.029658468266512 MRPL39 essential 0.643741329281921 1 1 2.48111408500499 -2.18304837673511 0.00819508934934962 503.517504935794 400.41424511188 1.25749148808406 0.209366694056866 -1564.20304161699 744.150904320562 -2.10199709835086 0.0362271768465699 JAM2 other 1 1 1 1.25749148808406 -2.10199709835086 2.96861751107381e-05 264.032781437533 97.8449956008863 2.69848018098477 0.00728402846221486 -427.211056160452 181.840288772185 -2.34937515247611 0.0193286118673526 ATP5J other 0.157336728086912 1 1 2.69848018098477 -2.34937515247611 2.19519215573936e-09 258.120882772644 53.7624205709796 4.80113953261947 2.29207205757382e-06 -204.561819496842 99.9149115566014 -2.04736026194608 0.0413265820744655 GABPA essential 1.54234200862248e-05 1 0.0203421395109676 4.80113953261947 -2.04736026194608 0.997661522744044 -27.2962644408342 435.253639206752 -0.0627134663149091 0.95002844699519 -0.282190120605211 808.898267677815 -0.000348857367954715 0.999721839600411 ADAMTS1 other 1 1 1 -0.0627134663149091 -0.000348857367954715 0.0075664790882272 46.1775319115669 31.6530011376437 1.45886741389112 0.145447699647843 -115.203823523663 58.8256030063464 -1.95839596427484 0.0509325016131142 ADAMTS5 other 1 1 1 1.45886741389112 -1.95839596427484 1.71221756742225e-09 36.4714186709104 15.0982866108717 2.4155998366496 0.0161176808881161 -146.668492517775 32.4089953307223 -4.52554887990433 7.77084799743093e-06 TSEN2 essential 1.20711338503269e-05 0.0661609998501269 1 2.4155998366496 -4.52554887990433 0.836542631310906 -11.4460813199761 34.0084143995703 -0.336566156407478 0.73660516533566 28.8291781877523 73.881295867415 0.390209427829856 0.696571383705925 SLFN13 other 1 1 1 -0.336566156407478 0.390209427829856 0.00129860777808596 -93.0685849226105 32.7909890730077 -2.83823658735629 0.0047472017804626 -231.438537950152 70.3869941766536 -3.28808667932743 0.00109000501920931 WNT7A other 1 1 1 -2.83823658735629 -3.28808667932743 1.83911775222657e-05 84.028029466875 69.2625779909354 1.21318079552095 0.225714558170001 -546.645627454502 148.674523444645 -3.67679421321992 0.000265514939612096 XPC ts 0.0995514439280243 1 1 1.21318079552095 -3.67679421321992 0.000230441645012508 49.2872250314431 29.1650688345733 1.68994029504968 0.0917509238838117 -172.311512102466 62.6038307551582 -2.75241163398406 0.00616153823901226 CCDC174 essential 1 1 1 1.68994029504968 -2.75241163398406 0.50218194133906 -30.4749351882746 32.5980600903152 -0.934869593584456 0.350370622666688 -72.1331091660459 69.972865430764 -1.03087259213958 0.303169465420867 FGD5 other 1 1 1 -0.934869593584456 -1.03087259213958 0.00021082417383312 103.904183472633 63.6916666627251 1.63136229458165 0.103532661589779 -184.95638938556 47.2723770165991 -3.91256799548318 0.000105836237691458 FLCN other 0.999306583968991 0.83991638231941 1 1.63136229458165 -3.91256799548318 0.00143612375641881 51.7121220879822 41.6135775283486 1.24267427026081 0.214652745650715 -219.073019635046 85.7395607076409 -2.55509846128151 0.0109527522984409 DPH3 essential 1 1 1 1.24267427026081 -2.55509846128151 1.38428794656157e-05 15.3742412856237 10.2611400381167 1.49829757985112 0.134776285572788 -73.1217411411064 21.1417929311262 -3.45863481774303 0.000596045680176561 OXNAD1 other 0.0758866652305051 1 1 1.49829757985112 -3.45863481774303 1.45071150927592e-16 337.834311195845 78.1831017126083 4.32106559851876 1.92327314231689e-05 -356.372102705693 120.74232158486 -2.9515094461326 0.00333207468994838 CXXC1 essential 1.19437078558686e-12 1 0.165055301073635 4.32106559851876 -2.9515094461326 9.7594263141138e-08 87.4734717132047 15.4212232308672 5.67227841810351 2.5635360648673e-08 69.2282391353178 23.8158151030864 2.90681796258765 0.00383657335190731 SKA1 essential 0.000629873374312905 1 0.00023684509703309 5.67227841810351 2.90681796258765 9.41592872343835e-22 410.890154951108 79.8759047470011 5.14410642674485 4.06682098454516e-07 -507.821745654035 131.925027701893 -3.8493207430022 0.000136127768245464 PPP4R1 other 8.17208453907215e-18 1 0.00368209971940719 5.14410642674485 -3.8493207430022 0.0048844791424123 -30.0327694892272 344.371808055643 -0.0872103023148007 0.930544297134251 -1402.20289281385 547.903128038445 -2.55921680504709 0.0108265375916928 APCDD1 other 1 1 1 -0.0872103023148007 -2.55921680504709 0.0630679187591996 116.724548961888 54.0169583530959 2.16088710880179 0.0312467265987844 58.1548025244742 85.9421699351229 0.676673658209641 0.498971038085148 PIEZO2 other 1 1 1 2.16088710880179 0.676673658209641 0.576663137418292 8.6029183472634 22.4142542723929 0.383814613804012 0.701302099274668 15.841861061444 16.6360080373054 0.952263369067832 0.341488623960467 CCDC144B other 1 1 1 0.383814613804012 0.952263369067832 2.43441503810442e-07 9.12713697701108 60.3093782282488 0.151338601808631 0.879778777676815 -392.998415538251 94.6085983154714 -4.15393973207173 3.93518828637984e-05 MPPE1 other 0.00153416835701341 0.322331272537372 1 0.151338601808631 -4.15393973207173 0.00954157707263103 45.4029637451623 40.0171872943494 1.13458658179041 0.25716911666549 83.8559912612749 29.9511845847864 2.79975541614702 0.00534022523651647 USP43 other 1 1 1 1.13458658179041 2.79975541614702 0.110625706789653 -1144.76395033921 644.348058617545 -1.77662357328322 0.0763273988522856 -2387.77001045771 1358.52038834475 -1.75762545114764 0.0795129940393893 RAB6B other 1 1 1 -1.77662357328322 -1.75762545114764 0.00160242178679745 -509.304265812586 329.562694594514 -1.54539416677371 0.122974786730712 -2433.66022832216 673.329744135928 -3.61436614009267 0.00033612867299477 EPHB1 other 1 1 1 -1.54539416677371 -3.61436614009267 4.68025149031851e-07 40.3826470405568 11.8555911657949 3.40621116870719 0.000719482331307337 -39.6707793110413 8.87373008482398 -4.4705866565501 9.94812873334312e-06 ZNF18 other 0.00289988382340135 0.0843004428863496 1 3.40621116870719 -4.4705866565501 0.774313632715001 8.0472502459447 25.6120376590336 0.31419797023086 0.753520624324897 -10.3046063926233 35.7068288035434 -0.288589234550022 0.773032571692362 DKK2 other 1 1 1 0.31419797023086 -0.288589234550022 1.29297597861489e-07 154.022559364214 78.1632152053015 1.9705248685032 0.0494090441424721 -310.141268494046 108.970655955826 -2.84609894079897 0.0046341383043362 CYP2U1 other 0.000827246031117807 1 1 1.9705248685032 -2.84609894079897 2.34184343249292e-06 54.9926099890402 10.6940519552808 5.14235485473625 4.11025328832712e-07 18.9954438703615 42.5397479210184 0.446534001697177 0.655433766100452 FBXL18 other 0.0137911159739508 1 0.00372060127659371 5.14235485473625 0.446534001697177 0.25383081309937 -10.7213957439397 32.7670458677632 -0.327200559586838 0.74367251541639 -60.1743010026648 44.9374154224801 -1.33906902381757 0.18124270641919 AK9 other 1 1 1 -0.327200559586838 -1.33906902381757 5.2950040369238e-09 101.714186142748 125.637430596026 0.809585054869506 0.418618286114923 -625.055832661751 172.301813049955 -3.62767995064874 0.000319669395665343 CDK19 other 3.65884778951435e-05 1 1 0.809585054869506 -3.62767995064874 5.64550031414809e-08 232.761255472546 79.3621170994627 2.93290128816538 0.00353427219890115 -139.766853259565 108.83887547564 -1.28416296703513 0.199763777154988 GTF3C6 essential 0.000368820535523295 1 1 2.93290128816538 -1.28416296703513 0.00360244593973522 65.5081148680983 20.872318209296 3.13851648921886 0.00181305002507303 30.4328864329724 23.5026653489763 1.29486958100682 0.196048934277675 TTC39B other 1 1 1 3.13851648921886 1.29486958100682 2.82218144702711e-52 177.463675646238 75.306512174352 2.35655151888284 0.0188849749255028 -719.230457029973 90.8148595239833 -7.91974420045247 1.97922629791452e-14 MMS19 essential 2.70421426254137e-48 1.91787028267917e-10 1 2.35655151888284 -7.91974420045247 2.27084897637131e-06 37.3487863959042 77.8961879675524 0.479468731017515 0.631844518447625 -234.246938590308 93.9378436668109 -2.49363759531421 0.0130120863937641 PI4K2A other 0.0133892640530195 1 1 0.479468731017515 -2.49363759531421 5.68056020796168e-30 25.3994387473772 61.0442286834099 0.416082556781982 0.677553388163753 543.66940544918 73.6154535984721 7.38526191001374 7.74375927633972e-13 MARVELD1 other 5.14090698820532e-26 7.44794767198354e-09 1 0.416082556781982 7.38526191001374 1.0443208286456e-28 52.1257233806366 74.2819875013142 0.701727634572438 0.483221727277216 -562.067563926258 89.5793479915228 -6.27452171207418 8.43474401168824e-10 ZFYVE27 other 9.40410906195363e-25 7.90588556215539e-06 1 0.701727634572438 -6.27452171207418 4.22094109335123e-05 -237.207670452567 165.228805558883 -1.43563145451677 0.151820982950539 -718.318125527925 199.255420718528 -3.60501171279367 0.000348019623522674 GOLGA7B other 0.219446727443331 1 1 -1.43563145451677 -3.60501171279367 0.44127381128655 15.9086980210108 22.0677399191606 0.720902914357708 0.471354718317512 -15.7566841277852 35.0529538600243 -0.4495108797594 0.653286025874694 GPR78 other 1 1 1 0.720902914357708 -0.4495108797594 4.89502154861877e-05 31.8798985249805 11.9887618824311 2.65914852906528 0.00812160232623472 -27.4542936759719 19.0432513090656 -1.44168100448804 0.150108603657732 TRMT44 other 0.251897808891922 1 1 2.65914852906528 -1.44168100448804 2.5835175777261e-21 46.4671799847786 67.5520929161063 0.687871803505581 0.491897624332654 -422.763311948959 81.463523559874 -5.18960257885527 3.23052635503822e-07 SLC25A28 other 2.23655116703748e-17 0.00289487466674975 1 0.687871803505581 -5.18960257885527 0.00057625506519562 500.925318409888 198.729563211853 2.52063814922132 0.0121328436407473 -622.795235254899 352.626550758364 -1.76616092553299 0.0781912086645561 HSPA13 other 1 1 1 2.52063814922132 -1.76616092553299 0.00225080939502067 -40.8864338093399 56.4294000743693 -0.724559073026738 0.469179261355072 289.7751833269 100.128558569698 2.8940313080128 0.00402801178135993 SAMSN1 other 1 1 1 -0.724559073026738 2.8940313080128 0.000566915718256482 194.244693168662 56.7431187307808 3.4232290630739 0.000687871737126864 -40.7460790849438 100.685222238309 -0.404687780183897 0.685940244474294 USP25 other 1 1 1 3.4232290630739 -0.404687780183897 6.03546542190427e-48 115.739578243944 61.3601455704025 1.88623376245333 0.0599247799749609 -577.799802466022 78.7924053848899 -7.33319156387663 1.0956953583558e-12 MOV10 other 5.73852052314658e-44 1.05307280891576e-08 1 1.88623376245333 -7.33319156387663 5.34604712616134e-47 1580.18106668347 416.172086679896 3.79694149910368 0.000167150544828006 -2899.52700681738 534.405507984566 -5.42570569257889 9.57099913351937e-08 RHOC other 5.07339872272711e-43 0.000868855301340889 1 3.79694149910368 -5.42570569257889 0.00141721160489336 0.949557912654219 7.83383413776179 0.121212409652257 0.903578381887893 -18.6106549267041 10.0594063029448 -1.85007488178065 0.064976061608868 PPM1J other 1 1 1 0.121212409652257 -1.85007488178065 4.8168738135105e-15 166.370494412836 241.72634468767 0.688259670776885 0.491653623528942 -1216.55917526062 310.40017858148 -3.9193249849928 0.000103010871677144 SLC16A1 other 3.87469329558784e-11 0.818627397218264 1 0.688259670776885 -3.9193249849928 0.00208013384765865 89.6095213563129 26.588058436711 3.37029202676138 0.000817395228014564 -11.0610247283622 67.932745538958 -0.162823166362663 0.870732761064966 HEATR3 other 1 1 1 3.37029202676138 -0.162823166362663 0.00568548504875366 145.720762471579 88.0216477561166 1.65551050436287 0.0985372458437496 -138.022439333095 131.255218487109 -1.05155772794398 0.293582312129705 OXA1L other 1 1 1 1.65551050436287 -1.05155772794398 0.0224599036327154 -19.6563153843557 58.8823139665268 -0.33382375895638 0.738672316156204 165.178469403898 87.8035254022607 1.88122821546349 0.0606039253249302 SLC7A7 other 1 1 1 -0.33382375895638 1.88122821546349 4.88253059428278e-11 43.5799987553739 230.134358161946 0.189367633340114 0.849892610957062 -2514.4181615222 418.319311431304 -6.01076281398286 3.89830920330807e-09 LARP1 other 3.62430246013611e-07 3.62230891171386e-05 1 0.189367633340114 -6.01076281398286 3.29925705346309e-06 185.879208413718 79.5203754734026 2.33750415924394 0.0198635535008297 -393.825728110026 144.54559926851 -2.72457778101185 0.00669668269067094 CNOT8 other 0.0191983767941017 1 1 2.33750415924394 -2.72457778101185 0.00121701552337842 -1131.54767891233 834.280778433327 -1.35631517369636 0.175697640064461 -5532.0073799879 1516.42403265039 -3.64806100462488 0.000296045403176246 GRIA1 other 1 1 1 -1.35631517369636 -3.64806100462488 7.56876321313288e-10 53.9751357756498 11.4157747999393 4.72811847829521 3.06207697474604e-06 -56.5493186531053 24.6688102904291 -2.29234073258268 0.022360471249354 C9orf85 other 5.41620695531789e-06 1 0.027093257072553 4.72811847829521 -2.29234073258268 0.512905080684646 -53.8934764191515 95.368182162694 -0.565109612000485 0.572288538100251 19.7617703561569 120.500175987273 0.163997854727151 0.869808481659533 PIK3AP1 other 1 1 1 -0.565109612000485 0.163997854727151 4.72259172419172e-05 141.084484526996 34.3478136121212 4.10752445905926 4.77897028397618e-05 110.273277616629 43.2150578655248 2.55173273074801 0.0110598665600501 SPAG17 other 0.243732958885535 1 0.40324951256191 4.10752445905926 2.55173273074801 0.355911681126318 -239.404237178034 180.733300762525 -1.32462715043643 0.18598713063967 -353.11525156722 360.447706370666 -0.979657368672764 0.327797303725251 FMN2 other 1 1 1 -1.32462715043643 -0.979657368672764 2.74757900180821e-08 236.982240309351 74.9634748361549 3.16130276547766 0.00167970568033779 -590.245896612305 164.530984865253 -3.58744522860362 0.000371594489224 RNF20 essential 0.000183098664680499 1 1 3.16130276547766 -3.58744522860362 0.0309628847189737 -18.2522727963753 20.1351464609609 -0.906488206170428 0.365175912135403 -99.5478470873884 37.831993528492 -2.6313138114812 0.00880563253831413 PPARGC1B other 1 1 1 -0.906488206170428 -2.6313138114812 0.941857241893057 2.47784973699504 70.3281830475518 0.0352326710235023 0.971910261473702 -38.7625345860308 132.139856597726 -0.293344760498991 0.769397580136303 SLC26A2 other 1 1 1 0.0352326710235023 -0.293344760498991 0.0650447124097747 43.1705968153625 26.9787912278533 1.6001679412083 0.110283991265224 -33.5679166160217 49.5068898316311 -0.678045353488846 0.498101791434754 LSM11 essential 1 1 1 1.6001679412083 -0.678045353488846 1.22469950593683e-11 19.6213686641551 10.8431116366348 1.80956992067312 0.0710494330277601 -103.521332198857 19.8974345697427 -5.20274771282716 3.0253656705339e-07 MED7 essential 9.21708848168058e-08 0.00271405554303596 1 1.80956992067312 -5.20274771282716 4.27118142607236e-44 566.514724333894 89.9799266248083 6.29601229501003 7.44393145597425e-10 -610.247748911365 101.414702381677 -6.01734989680965 3.75466028553988e-09 RRAGA other 4.02815120292884e-40 3.49033220143787e-05 7.02856008073089e-06 6.29601229501003 -6.01734989680965 0.424105955108066 220.280458994263 216.393909474226 1.0179605310033 0.309266464417495 30.0316167922849 244.279744109737 0.122939447565468 0.902212221186271 SLC24A2 other 1 1 1 1.0179605310033 0.122939447565468 0.00908601209832866 381.681373698525 178.676128575575 2.13616321744449 0.0332198651450307 -475.251864271648 390.227911611828 -1.21788280676446 0.223924175651597 PXYLP1 other 1 1 1 2.13616321744449 -1.21788280676446 0.00807061443083901 10.1243082262451 24.7266294297284 0.409449587741743 0.682409912702909 -145.403081324454 54.00285444108 -2.69250732816533 0.00736360583877706 RASA2 other 1 1 1 0.409449587741743 -2.69250732816533 6.53347510853261e-19 54.4600684540794 25.2365150064672 2.15798688686307 0.0314717319082125 -142.361364644735 33.2684150382237 -4.27917484139743 2.30566900247109e-05 RMND1 other 5.52862663684029e-15 0.191485810655224 1 2.15798688686307 -4.27917484139743 0.0316706955935644 138.413366776793 55.8088342494972 2.48013363185489 0.0135098926977954 57.7741474569554 90.8429744504774 0.635978156884886 0.525124348141105 TMBIM4 other 1 1 1 2.48013363185489 0.635978156884886 0.000826677143585221 -7.75460237535914 13.8406933704677 -0.560275570579822 0.57557924923769 -77.3097981225487 22.5292244702569 -3.43153392717148 0.000657418852198167 GRIP1 other 1 1 1 -0.560275570579822 -3.43153392717148 0.304929152972569 -2010.9099796397 1926.75363088385 -1.04367779429965 0.297233397565778 -5042.79836354361 3313.63399200169 -1.52183324281309 0.128801585240156 KIF5A other 1 1 1 -1.04367779429965 -1.52183324281309 0.00059512112725203 39.0699275274497 13.8749297188298 2.81586489583637 0.00508526049780142 -35.3442001761319 28.9439642327186 -1.22112506400137 0.222698584222396 CARNMT1 other 1 1 1 2.81586489583637 -1.22112506400137 6.70231167646036e-14 39.8875161936171 22.0304434695546 1.8105634708961 0.0708935298551613 -85.2439641973855 26.7074204235378 -3.19177078300899 0.00151583709477798 MCU other 5.29013460623016e-10 1 1 1.8105634708961 -3.19177078300899 1.57031730114936e-11 -2.80784551001369 121.786108687405 -0.0230555482909857 0.981616463167988 -535.436869287125 139.610215783152 -3.83522700171731 0.000143859534952311 ELMSAN1 other 1.17868016624271e-07 1 1 -0.0230555482909857 -3.83522700171731 0.283591942601503 -19.0780944529498 47.6416354625704 -0.400450032155981 0.689020326503592 33.9375220822052 57.7557682723088 0.587604028089375 0.557100909132558 CFAP70 other 1 1 1 -0.400450032155981 0.587604028089375 0.0229009915164527 -7.5980399285777 14.9038601673623 -0.509803490052631 0.610447093054956 69.5034889702225 31.0903769860649 2.23553059525058 0.0258880291073296 GNA14 other 1 1 1 -0.509803490052631 2.23553059525058 2.47335726877124e-53 130.608606867342 47.5113835513598 2.74899607430193 0.00622499086246303 -381.54341249433 54.4649515552463 -7.00530160404738 9.34135234055163e-12 FAM161B other 2.37417564229351e-49 8.91725494429058e-08 1 2.74899607430193 -7.00530160404738 3.3922935299568e-10 320.600294091507 161.481481799752 1.98536878977289 0.0477295189550542 -1686.86894614518 336.860389794653 -5.00762035920422 8.0167012581251e-07 GNAQ other 2.45635974504172e-06 0.00709478061344071 1 1.98536878977289 -5.00762035920422 0.0666274032815705 182.555832171234 78.3710478410581 2.32937847840787 0.0202949462658204 148.879038874901 127.568676042476 1.16705012149948 0.24382801163299 WIF1 other 1 1 1 2.32937847840787 1.16705012149948 3.28131796865267e-06 -11.1483845233348 15.6237053996204 -0.7135557307427 0.475881968076982 46.7766298807784 20.7792593718569 2.25112113207133 0.0248729130506633 GPR61 other 0.0191005518955272 1 1 -0.7135557307427 2.25112113207133 1.02428171854376e-09 126.216664703804 74.1788609839342 1.70151796656922 0.0895554341498827 -215.379519491227 89.9267429443692 -2.39505526875877 0.01703701516107 ADK other 7.28878870915742e-06 1 1 1.70151796656922 -2.39505526875877 0.00609039224846494 -181.524232404338 244.355814710515 -0.742868478981717 0.457960455922107 -725.406663320731 296.269532918316 -2.44846865006781 0.0147386024654154 KCNMA1 other 1 1 1 -0.742868478981717 -2.44846865006781 0.0988886950485277 15.0726102280083 7.33453124627114 2.05502024899972 0.0404695904826228 17.3844014481287 8.27796641600954 2.10008117627867 0.0362930501563462 BATF other 1 1 1 2.05502024899972 2.10008117627867 4.97685601039905e-05 8.34963793246928 53.2817399261768 0.156707306181028 0.875547734585204 -260.384392716107 79.1983902427061 -3.28774855042067 0.00109128302285499 DCK other 0.256009473174927 1 1 0.156707306181028 -3.28774855042067 0.409774096169522 30.8436034736287 44.5888201766163 0.691734012056322 0.48947088394166 -27.0131602067899 66.2771671064477 -0.407578678844317 0.683782154330936 ADAMTS3 other 1 1 1 0.691734012056322 -0.407578678844317 1.8636445979312e-16 3.10817349633061 13.2259962079582 0.235004868250333 0.81431478115724 -77.9349059200755 17.0642555125579 -4.5671436332351 6.4351981551152e-06 ALX3 other 1.53154313057986e-12 0.0549887682354594 1 0.235004868250333 -4.5671436332351 7.12617137378172e-58 109.018715178023 39.0916531069319 2.78879777429243 0.00552095933227508 -390.318618549924 50.4362731197201 -7.73884734947462 6.99140386933458e-14 DRAM2 other 6.88103107852363e-54 6.75649269932494e-10 1 2.78879777429243 -7.73884734947462 0.253083997375552 -25.9966886841342 39.4584435673036 -0.658837154582442 0.510349726823411 -125.860135165687 76.4442149191309 -1.64643113018862 0.100398916843217 ADAMTSL3 other 1 1 1 -0.658837154582442 -1.64643113018862 0.230841835149996 25.7303116704355 23.6175418671421 1.08945765038456 0.276552525735312 -8.88875233507062 34.5350439022409 -0.257383553941099 0.797003846680953 ART3 other 1 1 1 1.08945765038456 -0.257383553941099 5.625282062538e-09 15.5176429996547 16.1650431618432 0.95995060726366 0.337612108511378 -154.200150012752 31.6928881237958 -4.86544960530041 1.59825408506578e-06 WHAMM other 3.885382320595e-05 0.0140023040392613 1 0.95995060726366 -4.86544960530041 0.906613951876864 -2.67886248646861 31.3119079426821 -0.0855541122365457 0.931860060277208 -17.2010247826685 45.4545257118529 -0.378422709582537 0.705300365763839 CXCL13 other 1 1 1 -0.0855541122365457 -0.378422709582537 0.00050278489447348 12.3409150596537 41.3965808923619 0.298114356152798 0.765759542583307 -274.05528250919 81.9416392312404 -3.3445179408213 0.000896329824345175 N6AMT1 other 1 1 1 0.298114356152798 -3.3445179408213 0.000101219156438721 58.719835671944 23.0977512928079 2.54223170591624 0.0113636998938283 -89.1179935469342 45.720384695766 -1.94919605641873 0.0519203214725052 RWDD2B other 0.50174335846674 1 1 2.54223170591624 -1.94919605641873 1.15864547816036e-05 127.888398551812 59.7106269495574 2.14180297687797 0.0327692642516447 -338.097386883767 118.193013681345 -2.86055305938215 0.00443465966143804 USP16 other 0.0639688168492333 1 1 2.14180297687797 -2.86055305938215 2.95118100966122e-05 393.701559803405 120.166123174008 3.27631073887023 0.0011367310332515 -330.596899152094 237.860444043536 -1.38987758339333 0.165283493598515 CCT8 essential 0.156442105322141 1 1 3.27631073887023 -1.38987758339333 0.475378469348642 60.2636283484654 51.45403531121 1.17121286958296 0.242160314624611 23.7742365123436 101.849667474364 0.233424782838173 0.815542393187046 MAP3K7CL other 1 1 1 1.17121286958296 0.233424782838173 0.0059346179987659 -259.365287574097 124.120812968031 -2.08961963245358 0.0372377096936338 -770.956488707132 245.688476151209 -3.13794322299694 0.00181815328504156 TIAM1 other 1 1 1 -2.08961963245358 -3.13794322299694 0.000123286654428455 105.931166115429 52.3151630900502 2.02486544738643 0.0434957682933572 -251.107854098733 103.551955394617 -2.42494555647751 0.0157197856117277 SCAF4 other 0.603858033390573 1 1 2.02486544738643 -2.42494555647751 1.0663969701821e-07 89.4937780325771 27.0679858123114 3.30625923380943 0.00102332772507897 -172.307821580728 58.1628877440167 -2.96250458435076 0.0032176264783832 CDK20 other 0.000685693251827089 1 1 3.30625923380943 -2.96250458435076 5.21747517296444e-24 39.5134678676605 12.7070200998866 3.10957782053191 0.00199608542525237 -48.4325845498107 15.2161044327735 -3.18298187054324 0.00156176488322813 PCGF6 other 4.59398688979519e-20 1 1 3.10957782053191 -3.18298187054324 0.0124180436217301 -57.1962129045015 106.017538889926 -0.539497648251256 0.589819553568289 -275.099220142112 125.543098680152 -2.19127314073222 0.0289616867273014 ANKRD9 other 1 1 1 -0.539497648251256 -2.19127314073222 1.29438726709271e-18 20.6997895557291 12.8999958337988 1.60463536751651 0.109296480030194 -58.1493115094832 15.4304526418024 -3.76847736481508 0.000186780598769625 SFR1 other 1.09194509851941e-14 1 1 1.60463536751651 -3.76847736481508 3.62825127150058e-26 129.398416849321 86.1285608577939 1.50238684543876 0.133717830894584 -511.939318542385 102.900114929386 -4.97510929792157 9.38526788592131e-07 SORCS3 other 3.23095775727127e-22 0.00828625301647992 1 1.50238684543876 -4.97510929792157 2.162186315312e-08 26.5921209613657 20.9274263088326 1.27068281445303 0.204517546222393 -55.0948924967339 24.9970883595423 -2.20405239619447 0.0280413177794697 SFXN2 other 0.000145147567346894 1 1 1.27068281445303 -2.20405239619447 2.43670449398658e-09 142.432370478914 102.137330880907 1.39451823589351 0.163876204553168 -336.241456540977 120.434013184251 -2.79191440732415 0.00547167307569918 C14orf2 other 1.70934820253159e-05 1 1 1.39451823589351 -2.79191440732415 0.301194392988761 -16.4858921969254 29.3990579314197 -0.560762601148058 0.575250103649605 -45.6513372683831 34.1109651419391 -1.33831854591107 0.181496567477301 TDRD9 other 1 1 1 -0.560762601148058 -1.33831854591107 0.0155709637759698 -84.0622760881166 176.125341054627 -0.477286661787323 0.633397164768518 -980.342023020043 348.779126381674 -2.8107818067852 0.00516481309292344 PCDH1 other 1 1 1 -0.477286661787323 -2.8107818067852 3.89863170541619e-06 -284.666934713014 207.492096992855 -1.37194109481103 0.170784043640103 -2060.29022844628 410.87283170372 -5.01442312431101 7.74032186945345e-07 PPP2R2B other 0.0225535844158326 0.00685250695102714 1 -1.37194109481103 -5.01442312431101 3.39769864510762e-36 109.492907271023 30.894547220622 3.54408519047455 0.000436454214155087 -196.955684653257 37.5166245451053 -5.24982423236029 2.38107972511625e-07 SUPV3L1 essential 3.14117239740199e-32 0.002140352564907 1 3.54408519047455 -5.24982423236029 4.98627042037665e-10 3053.75481284609 7001.69159849322 0.436145290018667 0.662947193271665 -43037.0463075809 9803.0336044006 -4.39017635196736 1.42284060591634e-05 EEF1A1 essential 3.5955996001336e-06 0.119431512369516 1 0.436145290018667 -4.39017635196736 0.00533802879242654 -66.707811574519 41.0821387502205 -1.62376676589558 0.10514665729694 -148.803449740639 49.8878706328201 -2.98275809035523 0.00301654028226259 HKDC1 other 1 1 1 -1.62376676589558 -2.98275809035523 0.0281734637760297 -414.172662031929 381.665839852647 -1.08517089764133 0.278444247423564 -1080.5814781355 463.473826406696 -2.3314832824827 0.0201816501771476 HK1 other 1 1 1 -1.08517089764133 -2.3314832824827 9.61204964128653e-16 18.3139490762053 45.9613422638466 0.398464191299547 0.690483106097784 -269.187929407989 55.8200159892926 -4.82242659084198 1.96298781841277e-06 TYSND1 other 7.81940238318659e-12 0.0171408096303803 1 0.398464191299547 -4.82242659084198 0.00605956099126106 -93.421702227639 89.5964677948395 -1.04269403166159 0.29766782116945 174.675325628863 125.443569210821 1.39246138106373 0.164492451578007 CD109 other 1 1 1 -1.04269403166159 1.39246138106373 0.352636283576457 -23.53461582767 16.6983735948615 -1.4093956931777 0.159429413639453 -32.5901393848635 38.9219775171518 -0.837319721756224 0.402870555420247 LRFN2 other 1 1 1 -1.4093956931777 -0.837319721756224 1.06742366392314e-07 -6.73780659712448 8.53181715165525 -0.789727027356334 0.430114516272299 28.6421940890503 10.3592522785436 2.76489010199846 0.00593465679042593 NODAL other 0.000686139931169794 1 1 -0.789727027356334 2.76489010199846 0.0190577931502499 141.085924349062 200.975363372964 0.702006066719924 0.483049953831121 -1132.12808237484 479.282188819533 -2.36213259909211 0.0186086691423848 UBE2L6 other 1 1 1 0.702006066719924 -2.36213259909211 0.160888347018508 107.790323888765 56.7071451490375 1.90082437769476 0.0579842062170296 53.1527606161952 134.148904033799 0.396222101097475 0.692135022567803 ZDHHC5 other 1 1 1 1.90082437769476 0.396222101097475 6.86732515913893e-07 129.436431641772 25.3841422773341 5.09910597835515 5.09821922249409e-07 -3.55573472513167 60.0498377654652 -0.0592130613078289 0.952809536154379 MED19 essential 0.00420898359003625 1 0.00460420177983441 5.09910597835515 -0.0592130613078289 7.73044038023147e-07 256.672299732835 128.090327672182 2.00383826318041 0.0457027372832672 -1161.2231952278 300.727161609623 -3.86138448224106 0.000129748245791873 ZFAND3 other 0.00472407211635945 1 1 2.00383826318041 -3.86138448224106 0.0677721550003133 -138.254534206489 262.170165580515 -0.527346557150608 0.598220564937717 -982.422096146314 454.848635331478 -2.1598879711497 0.0313245120335393 NPTN other 1 1 1 -0.527346557150608 -2.1598879711497 4.43918503763843e-20 -83.5866152396668 169.053591669749 -0.494438564801129 0.621244376596408 -1285.80658932988 204.943007755275 -6.27397149779943 8.462150714763e-10 KAT6B other 3.79594712568462e-16 7.93072764987589e-06 1 -0.494438564801129 -6.27397149779943 1.00970450912881e-37 -14.7558650335626 203.764890189739 -0.0724161312570704 0.942303803536964 -2123.7542397833 247.023379142325 -8.59738153998646 1.45891031253829e-16 SAMD8 other 9.37409666275183e-34 1.42302111884985e-12 1 -0.0724161312570704 -8.59738153998646 0.0139048087707068 15.8301389634006 5.46619345237419 2.89600781628482 0.00396863040823563 6.13013279146947 12.9310864231151 0.474061698366773 0.635692138971592 GLYATL2 other 1 1 1 2.89600781628482 0.474061698366773 0.360589463938642 -25.7804588439846 18.6751894214977 -1.38046572177243 0.168147375473599 -38.2204811783504 43.8451271794876 -0.871715596168491 0.383841116917979 MAPK13 other 1 1 1 -1.38046572177243 -0.871715596168491 1.68869795798973e-30 41.8054156537542 49.2526881074679 0.848794599038656 0.396459243503273 -386.599876102358 63.5460982546206 -6.0837704708998 2.56225740967937e-09 MFSD14A other 1.53114243850929e-26 2.38597409989343e-05 1 0.848794599038656 -6.0837704708998 1.28098853193425e-48 49.7501773812713 7.2267080078027 6.88421025556255 2.02272991062146e-11 -23.3288030566013 9.32393976384112 -2.50203279380589 0.0127118963431337 SASS6 essential 1.21937298354822e-44 1 1.93312297558093e-07 6.88421025556255 -2.50203279380589 2.62596531515754e-13 23.896196227776 16.0230614029762 1.49136270696294 0.136589429611198 -120.880749036663 24.2265657288695 -4.98959490955072 8.75752623461873e-07 GALK2 other 2.04956592848046e-09 0.00773902593353257 1 1.49136270696294 -4.98959490955072 7.42046113370924e-05 171.309060277059 178.952739170215 0.957286605789895 0.338951901819465 -1508.33302134031 416.797266341742 -3.61886495700668 0.000330507839553082 LHFPL4 other 0.37382673769714 1 1 0.957286605789895 -3.61886495700668 0.430605184783149 17.3062583222371 45.5320985067275 0.380089187404356 0.704063452062081 -54.317629097864 75.6469376787856 -0.718041347932803 0.473114604860321 B3GNT7 other 1 1 1 0.380089187404356 -0.718041347932803 0.666871515450572 167.308405492873 188.916959939218 0.885618768937964 0.376310049263079 124.596868713375 288.376679566296 0.432062914729314 0.665908793760237 BUB1B other 1 1 1 0.885618768937964 0.432062914729314 2.41876739695247e-12 17.9178448827599 41.8578744017249 0.428063898104237 0.66881500319482 -372.241746468362 68.197549253988 -5.45828626600676 8.06395097905799e-08 PDE6D other 1.84818016801138e-08 0.000733819539094277 1 0.428063898104237 -5.45828626600676 3.60887056993818e-05 107.496748276105 31.2022094455645 3.44516462732053 0.00062572124777959 -109.124549993952 73.2389287015431 -1.48998015029203 0.136949184637819 BRPF1 other 0.18910481786476 1 1 3.44516462732053 -1.48998015029203 3.83972587043441e-06 72.7237265298112 22.704770924767 3.20301520639797 0.00145918902124182 -129.304293777298 53.2934407047338 -2.42627032646839 0.0156576831876238 RPUSD3 other 0.0222243333380744 1 1 3.20301520639797 -2.42627032646839 0.723428170196344 24.7179696998041 51.5766390264933 0.479247391190172 0.632002924373396 86.242580816112 109.263399708238 0.789308963901935 0.430360460642406 SST other 1 1 1 0.479247391190172 0.789308963901935 6.32113354109657e-06 187.319535590461 61.5893290859844 3.04142841577224 0.00249598407270654 -329.063741055931 137.251282484239 -2.39752762305677 0.016923990761254 TATDN2 other 0.0358345060444765 1 1 3.04142841577224 -2.39752762305677 0.062736132399805 8.43547332420685 3.62950599059938 2.32413814608798 0.0205746946769337 4.35763580168509 8.08832243161024 0.538756440353425 0.59032863139421 GHRL other 1 1 1 2.32413814608798 0.538756440353425 4.92715681293019e-08 363.550855949305 82.9356709455448 4.38352824308868 1.46360693829503e-05 -353.739235361361 184.821419065551 -1.91395151682013 0.0562777518146972 SEC13 essential 0.000323369301632608 1 0.126309278774861 4.38352824308868 -1.91395151682013 6.88325581808583e-09 46.3422017103304 18.8268581740947 2.46149417400383 0.0142204233819667 -110.672548753449 32.0271347711129 -3.45558694352113 0.00060264291148716 EXOG other 4.73912163075209e-05 1 1 2.46149417400383 -3.45558694352113 3.23129480571256e-06 -26.6100240037077 68.2944322301344 -0.389636799586222 0.696994953181675 -267.585402658657 87.729016043984 -3.05013568742752 0.00242654127453024 ZFYVE9 other 0.0188158296536642 1 1 -0.389636799586222 -3.05013568742752 0.232054836272564 -376.525210084046 452.354832630756 -0.83236694498054 0.405656490967202 -1717.12477718361 1008.08230216583 -1.70335772535081 0.0892121220944339 ATP2B2 other 1 1 1 -0.83236694498054 -1.70335772535081 0.00851435098939266 -341.510471507095 625.400498418913 -0.546066836164144 0.58529929162549 -4173.8486259763 1381.64385083923 -3.02092946995064 0.00266824686082374 SLC6A1 other 1 1 1 -0.546066836164144 -3.02092946995064 0.134469913267352 448.485895428495 575.725118848813 0.778993100605479 0.43640444131859 -1694.62832208221 1235.81391514421 -1.3712649625607 0.170994494149433 TIMP4 other 1 1 1 0.778993100605479 -1.3712649625607 0.648463508175638 -375.600143740864 538.436563614686 -0.697575478937292 0.485812839368713 -980.001817295109 1155.77273937252 -0.847919131426447 0.396946122561218 SYN2 other 1 1 1 -0.697575478937292 -0.847919131426447 2.23861115257589e-80 35.7593686587531 28.5723310464978 1.25153837118012 0.211406116650103 -430.579345867409 36.6878311497498 -11.7362987228626 7.61349761139405e-28 CPT2 other 2.19831615182953e-76 7.4947270486563e-24 1 1.25153837118012 -11.7362987228626 1.33811126969647e-80 305.634018428531 89.9704564560479 3.39704865872097 0.000743363005612961 -1122.12528213707 114.961702615406 -9.76086171836756 1.7026767945719e-20 NECAP2 other 1.31456051134981e-76 1.67083673851341e-16 1 3.39704865872097 -9.76086171836756 2.23310245137294e-17 -39.2836526277329 117.921809627612 -0.333133054451823 0.73919325161367 698.103399126449 151.41555771037 4.61051301255179 5.27835426583802e-06 LRP8 other 1.85593144733605e-13 0.0452830012466244 1 -0.333133054451823 4.61051301255179 0.0220966457548586 228.034074611103 155.319213138579 1.4681639830846 0.142777436660151 -3.88740913524867 199.445002809448 -0.0194911332973469 0.984458185975128 SSBP3 essential 1 1 1 1.4681639830846 -0.0194911332973469 0.0922759374949057 18.9462312835244 379.381712579972 0.0499397589690901 0.960193158762815 963.275488455025 565.722533537069 1.70273487681732 0.0893271560204938 MMP14 other 1 1 1 0.0499397589690901 1.70273487681732 0.149143485441444 23.9638819697259 20.6086833736823 1.16280509216461 0.245544629551613 -42.2884891741716 42.6318164325548 -0.99194668941854 0.321773709141061 SUSD3 other 1 1 1 1.16280509216461 -0.99194668941854 2.22116327886154e-12 124.828546828662 48.1885708296222 2.59041811532472 0.00990559535913857 -273.014776097337 72.3924667331571 -3.77131472952407 0.000184682507167318 ZFHX2-AS1 other 1.69918990832908e-08 1 1 2.59041811532472 -3.77131472952407 0.102185937973177 -0.516521725602258 16.8238623082596 -0.0307017328208086 0.975521393788593 80.6885996981904 40.1522651709226 2.00956532227286 0.0450900855749148 CLEC18A other 1 1 1 -0.0307017328208086 2.00956532227286 0.0696313093578316 49.1282543902165 38.0385442581053 1.29153876281026 0.197198055874985 2.70332763822396 49.5319124709069 0.0545774936473892 0.956499954623578 C1orf158 other 1 1 1 1.29153876281026 0.0545774936473892 0.161750698464314 -2.17373481230249 14.9116032746677 -0.14577472135376 0.884166294645304 62.3010236624712 35.5884182738531 1.7505982756262 0.0807152374108344 CLEC18C other 1 1 1 -0.14577472135376 1.7505982756262 0.338213786165951 5.64191510114082 10.5373988613438 0.535418197164204 0.592632452539101 -26.3524094256674 24.7394327730226 -1.06519861095617 0.28737290182986 ARMC12 other 1 1 1 0.535418197164204 -1.06519861095617 4.60847701119215e-06 143.626020939966 34.2168287766441 4.19752578117359 3.26935204508754e-05 -99.3665271706156 81.6627690582898 -1.21679105810984 0.224338969259564 DDX19B other 0.0265079597683772 1 0.277927617352892 4.19752578117359 -1.21679105810984 2.03548099979718e-05 194.74712581092 48.4865758832158 4.01651637104641 6.95008675433156e-05 -113.363376841581 115.71931679072 -0.979640910312323 0.327804184608854 ST3GAL2 other 0.109651361459074 1 0.582417270012985 4.01651637104641 -0.979640910312323 0.0466669908392959 66.8866814978465 30.297627885605 2.2076540694998 0.027786010407865 -24.731864216929 72.3091027864338 -0.342029748176726 0.732492555647023 FUK other 1 1 1 2.2076540694998 -0.342029748176726 0.119601577096341 -31.3640302431589 29.0009522276126 -1.08148277328964 0.280077492396821 90.0665147248712 69.2144231042996 1.30126801156963 0.193850804215534 IL34 other 1 1 1 -1.08148277328964 1.30126801156963 1.70271461603292e-05 109.70592254787 31.6061130139329 3.47103493870024 0.00056989448709909 -8.15036039024788 46.8765183893326 -0.173868722983118 0.862048962267655 DHRS1 other 0.0925255122352291 1 1 3.47103493870024 -0.173868722983118 4.41238851341648e-06 -13.3393326836676 46.2805728386733 -0.288227475709223 0.773308959678632 -300.301585932715 71.3846402452804 -4.20680954475455 3.14296496093864e-05 CACNA1D other 0.0254285950028192 0.259357468576657 1 -0.288227475709223 -4.20680954475455 0.558970762522178 10.4333319254983 120.578364298493 0.0865273964048019 0.931088610961476 -180.765004012331 207.839474104665 -0.869733744232345 0.38494507605753 KIT other 1 1 1 0.0865273964048019 -0.869733744232345 0.651070541410636 -45.8358250750635 51.5430013247872 -0.889273497797283 0.374344247379839 -5.99274257533536 123.013860847044 -0.0487159945559856 0.961167835034481 HYDIN other 1 1 1 -0.889273497797283 -0.0487159945559856 1.37890943183356e-13 113.641029909238 19.5105674862699 5.82458864864951 1.12947897603972e-08 -60.0102556434247 36.0272869690472 -1.66568900108916 0.0965105145040547 AASDH other 1.08313335870526e-09 1 0.000105018955192173 5.82458864864951 -1.66568900108916 0.000211166175099447 24.3511488977742 6.92578108411605 3.51601481508308 0.000483762418446664 -15.1991319093326 16.5292483681742 -0.919529525528661 0.358324791137422 ZNF19 other 1 1 1 3.51601481508308 -0.919529525528661 0.017646011093175 -42.0170157068085 57.0970187694012 -0.735888083342906 0.462193607859067 -241.204464039683 90.0620776664988 -2.6782023054461 0.00768086228753802 CACNA2D3 other 1 1 1 -0.735888083342906 -2.6782023054461 1.08505337003036e-06 9.03001326553303 53.0443884802781 0.170235033794204 0.864904084175379 -334.566604023875 82.4577011323101 -4.05743307695464 5.87718248979591e-05 RNF111 other 0.0065580625684635 0.475699150724081 1 0.170235033794204 -4.05743307695464 0.000284807385709315 215.121904709264 53.8659050509746 3.99365618206338 7.63226403293628e-05 153.982605571524 83.7347517271514 1.83893308805971 0.0666033455716456 CCNB2 other 1 1 0.638515208995449 3.99365618206338 1.83893308805971 0.0787617875998922 -126.691286203848 82.8972276977032 -1.52829340283666 0.127163177869694 -290.656768184833 128.864051825873 -2.25553025895525 0.0245939361242413 FAM81A other 1 1 1 -1.52829340283666 -2.25553025895525 0.2490683549562 -143.306516692458 97.7073207893022 -1.46669170267688 0.143179179888763 -233.643273269951 151.886397164867 -1.53827648578917 0.124704753343456 MYO1E other 1 1 1 -1.46669170267688 -1.53827648578917 1.00840152875796e-07 172.740161731394 128.655263246157 1.34265911376582 0.18008097834089 -860.223814497926 212.244628202433 -4.05298273875496 5.98825999784741e-05 APPL1 other 0.000650116465590254 0.484390351225877 1 1.34265911376582 -4.05298273875496 0.55183464206295 29.6574068869927 60.4678483301797 0.490465721966009 0.624050549961175 -78.7779666891473 116.482845219379 -0.676305309513861 0.499204599246016 AFAP1L1 other 1 1 1 0.490465721966009 -0.676305309513861 0.00631521568068119 16.1858291269445 54.3539791407713 0.297785541791244 0.766008368253479 -296.785059957797 107.407671326701 -2.76316445829153 0.00596613257788853 DSCR3 other 1 1 1 0.297785541791244 -2.76316445829153 2.60979860233745e-05 171.154506056622 83.9236031577484 2.03940845741463 0.0420089305972733 -485.337252673088 165.836624135646 -2.92659872451399 0.00360525597010935 DYRK1A other 0.139102265504586 1 1 2.03940845741463 -2.92659872451399 0.11919301587692 -19.1279528258327 41.9606726717664 -0.455854294221148 0.648720679136874 -167.53077155341 82.9160812991637 -2.02048588076605 0.0439411057493314 KCNJ6 other 1 1 1 -0.455854294221148 -2.02048588076605 0.487660564284493 -30.7796234173792 27.3901284108185 -1.12374878115657 0.261735137947387 -48.4716480900333 54.7137594639037 -0.885913316229193 0.37615036044722 ERG og 1 1 1 -1.12374878115657 -0.885913316229193 0.0420189235141547 -48.8119567770764 141.566187139247 -0.344799544039877 0.730410579050152 562.788264706864 275.717799663265 2.0411749455211 0.0418322946269935 ETS2 other 1 1 1 -0.344799544039877 2.0411749455211 0.371349065408434 -121.284886881116 110.436153830097 -1.09823533937726 0.272716298491342 -196.7511552225 146.077715830101 -1.34689370041448 0.178723883231037 TSPAN18 other 1 1 1 -1.09823533937726 -1.34689370041448 0.0113774091175846 32.4698731501057 12.0260224014974 2.69996779201599 0.00720318817753556 2.63847780126848 23.4221780090786 0.112648695618562 0.910360686458487 LCA5L other 1 1 1 2.69996779201599 0.112648695618562 0.921077413172711 -307.829868451958 796.47970207105 -0.386488026815401 0.699322952100593 -451.799691264803 1551.24352339501 -0.291250009718659 0.770997990468869 MX1 other 1 1 1 -0.386488026815401 -0.291250009718659 0.00272808337607958 142.995052428146 72.8505220818377 1.96285556152241 0.0503012706259957 -126.641107222398 97.4172808458389 -1.29998606122876 0.194295734331853 CREB3L1 other 1 1 1 1.96285556152241 -1.29998606122876 0.917442399745693 -24.6705082422542 63.9319036850855 -0.385887277246987 0.699767513436249 -39.8926703459223 127.708594418769 -0.312372636528363 0.754906002567055 C2CD2 other 1 1 1 -0.385887277246987 -0.312372636528363 1.51619859005596e-17 852.431124250803 93.1792536222419 9.1482931136865 2.21707168204396e-18 198.971848324018 244.490983756518 0.813820801351794 0.416190825301967 SLC38A10 other 1.26223532622159e-13 1 2.16231001149747e-14 9.1482931136865 0.813820801351794 0.000408712734780863 4.78148546824553 3.18337128585631 1.50201941240396 0.133814319797608 -17.7582077502691 6.43952903729006 -2.75768734754278 0.00606523904907702 C9orf43 other 1 1 1 1.50201941240396 -2.75768734754278 0.089171696631243 74.4880423596883 34.2103953173529 2.17735111414819 0.0299874886476667 83.1689432653428 71.2788840930281 1.166810400073 0.243921814543986 ZNF618 other 1 1 1 2.17735111414819 1.166810400073 0.0670722084620135 26.4566508052379 51.5648999386369 0.513074801594142 0.608157673101128 -203.672940872935 107.437768312789 -1.89572944478865 0.0586538202908294 TMEM268 other 1 1 1 0.513074801594142 -1.89572944478865 0.247869003898723 1033.71603788458 799.231361756202 1.29338773144878 0.196560249562094 -144.078405525042 1364.37929758166 -0.105599964599594 0.915948207053459 SNX22 other 1 1 1 1.29338773144878 -0.105599964599594 0.0442278732778944 32.387758712188 15.5343900283559 2.08490701296083 0.0376589905223013 -0.0437215451505814 25.2904920244847 -0.00172877400361578 0.998621429292876 SLC34A2 other 1 1 1 2.08490701296083 -0.00172877400361578 0.786025565138675 -112.642180519261 196.774936395874 -0.572441707172737 0.567316472654475 11.0004688948847 374.498442001801 0.0293738709194198 0.976579790989811 ACAN other 1 1 1 -0.572441707172737 0.0293738709194198 4.48025977439196e-19 272.65685613644 29.1922465423138 9.34004362224153 4.94934023264251e-19 -31.2657269202502 108.690592857859 -0.287658076915067 0.773744848393111 PSMG3 essential 3.79567608086487e-15 1 4.83501047326847e-15 9.34004362224153 -0.287658076915067 0.135391408476546 -179.480200961597 143.844494513038 -1.24773771543498 0.212795307415935 -528.640249941485 269.938451641917 -1.95837327630058 0.050821963352426 CABP1 other 1 1 1 -1.24773771543498 -1.95837327630058 1.79305724112009e-09 68.7157841205289 70.0918319096115 0.980367929449225 0.327446962397868 -541.318866626981 113.701616540595 -4.76087221181869 2.62543978254988e-06 WDR19 other 1.26374674354144e-05 0.0227940681920981 1 0.980367929449225 -4.76087221181869 4.76956817349757e-10 174.413828711117 90.4589474296254 1.92809925017983 0.0544888892047443 -763.075845064483 172.159806009867 -4.43236933608503 1.17947691819112e-05 AP3S2 other 3.44267430763055e-06 0.0995478518953309 1 1.92809925017983 -4.43236933608503 1.7087756259368e-13 560.35405974826 88.0488088776861 6.36412992851137 4.96815218343422e-10 -237.907316370429 165.2323171479 -1.43983526029885 0.150629979094238 SPPL3 other 1.33865482535889e-09 1 4.69639425900037e-06 6.36412992851137 -1.43983526029885 7.61934230726555e-10 85.4985827369941 31.7006512113122 2.69706076910131 0.00726656640675672 -177.214554326438 50.9586549078162 -3.47761444345455 0.000556696843956706 RAB28 other 5.45011555238705e-06 1 1 2.69706076910131 -3.47761444345455 8.60834773233881e-28 136.184214007887 71.7363412368761 1.89839921662859 0.0583005543304083 -429.203159315215 91.6583619940573 -4.68264051394506 3.78332006228803e-06 FAM213B other 7.72943542886702e-24 0.0326651854177949 1 1.89839921662859 -4.68264051394506 9.86560995083021e-07 49.3728335935236 53.7029205345193 0.919369619046838 0.358408301985737 -138.184116106156 68.6168495022261 -2.01385107460629 0.044636175555836 TNFRSF14 other 0.00598349243517852 1 1 0.919369619046838 -2.01385107460629 2.08041164251834e-16 82.7842501697851 35.7768884707865 2.31390301695415 0.0211350558648961 -117.826640735938 45.7125487296342 -2.57755570429514 0.0102761024401658 PANK4 other 1.70801795850755e-12 1 1 2.31390301695415 -2.57755570429514 0.271318913100944 -315.493701510656 409.105253344158 -0.771179785475031 0.441018096921443 527.140461233122 715.34128371158 0.736907645673728 0.461574853510084 MEGF11 other 1 1 1 -0.771179785475031 0.736907645673728 2.69838586838916e-05 50.4567827130843 32.2840885845523 1.56289940107609 0.118800106493515 -205.643757503001 62.3012366106927 -3.30079736278793 0.00104314346814506 C12orf43 other 0.143554128198303 1 1 1.56289940107609 -3.30079736278793 1.31797325688665e-47 345.126840067387 93.3782207516913 3.69601002556194 0.000246777372533489 -657.606417414155 119.310444503403 -5.51172548347514 6.0773625019219e-08 PEX10 other 1.25246998601938e-43 0.000553830044800143 1 3.69601002556194 -5.51172548347514 2.05271450592578e-67 586.09374932354 101.91516067108 5.75080042521931 1.66851362246428e-08 -769.546330619531 130.220702077803 -5.90955445901181 6.90159172276135e-09 RER1 other 2.00037028602468e-63 6.38949361693246e-05 0.000154754638483562 5.75080042521931 -5.90955445901181 6.14299237315534e-13 83.384706953295 10.7680058147986 7.74374646405727 6.81401232041856e-14 51.8734589081063 42.9154897847445 1.20873510166826 0.227419741850576 RADIL other 4.75160460063566e-09 1 6.58983131507679e-10 7.74374646405727 1.20873510166826 3.72323653307643e-35 -75.7276272292385 138.703306341495 -0.545968435985175 0.585365597534027 -1382.21100577794 177.226251848784 -7.79913241610104 4.60189701410608e-14 SKI other 3.43133478888324e-31 4.45187517144622e-10 1 -0.545968435985175 -7.79913241610104 5.12650967682584e-40 764.880194144356 53.6200399198302 14.2648195579109 3.79997437007488e-38 -389.462846406764 213.29454833798 -1.82593905677155 0.068544804530649 WIPI2 other 4.78816003815533e-36 1 3.74069476990171e-34 14.2648195579109 -1.82593905677155 0.230689191714183 -12.8263881270667 78.3729145054145 -0.16365842980333 0.870075532911543 -105.622339063977 100.626052600556 -1.04965201689124 0.294456940303635 LDLRAP1 other 1 1 1 -0.16365842980333 -1.04965201689124 5.5525708813971e-08 -330.829339496433 240.445739958152 -1.3759001908456 0.169557263404886 -1860.54284511981 365.926137921565 -5.08447648940183 5.47860347421449e-07 AGAP1 other 0.000362971558516928 0.00487212206961894 1 -1.3759001908456 -5.08447648940183 2.88693922913457e-44 35.6240969142291 15.4459631239432 2.30636941370184 0.0215559923365363 -128.285301968896 19.8316766396223 -6.468706821923 2.64720715272163e-10 PAFAH2 other 2.72382716268847e-40 2.49578690358595e-06 1 2.30636941370184 -6.468706821923 0.000675601981264064 -23.5442936471865 66.533823877028 -0.353869539960646 0.723606933551112 149.320364072641 85.4253807379257 1.74796252334815 0.0811711997115977 EXTL1 other 1 1 1 -0.353869539960646 1.74796252334815 0.323857622863395 24.622427745665 16.6213657045852 1.48137211967321 0.139226457179457 12.4331098265897 33.1313282507305 0.375267472903553 0.707643209184934 WDR66 other 1 1 1 1.48137211967321 0.375267472903553 5.01627823505965e-18 169.752959202731 35.3804901057689 4.79792559953973 2.20217512399137e-06 -84.286321661143 42.7795387328017 -1.97024849163499 0.0494393666020723 MRPL17 essential 4.19611674362739e-14 1 0.0195575172761674 4.79792559953973 -1.97024849163499 1.06317613076847e-07 -65.7628312620477 44.9612882945615 -1.46265451361638 0.144279100381338 -243.413003390325 57.727557912941 -4.21658237747415 3.01495873873868e-05 GRHL3 other 0.000683834887310281 0.249153246502964 1 -1.46265451361638 -4.21658237747415 1.57574973831674e-27 434.833808710374 109.951602365195 3.95477464044687 8.93213022094009e-05 -376.506242588557 141.171165994486 -2.66701942947232 0.00793620126584272 UBXN11 other 1.41313236532245e-23 1 0.744135768706519 3.95477464044687 -2.66701942947232 0.0441091642840134 49.2019207905104 20.630494107262 2.38491237944665 0.0175086612212678 7.57551850775486 44.9889113588894 0.168386348523146 0.86635725183478 PTPDC1 other 1 1 1 2.38491237944665 0.168386348523146 0.0174540191398484 -7.97314979833045 30.770532827167 -0.25911640344723 0.795667162984667 -183.045657067818 67.2027139834169 -2.72378370184553 0.00671193381079814 NCK1 other 1 1 1 -0.25911640344723 -2.72378370184553 0.975649171139911 4.30641618497125 66.3619942559893 0.0648928085005912 0.948288953106024 29.1336473988438 132.27920341478 0.220243595718453 0.825784062469165 HPD other 1 1 1 0.0648928085005912 0.220243595718453 1.27071817229713e-09 588.053371598117 90.9776721215902 6.46371090713547 2.73404817365584e-10 864.699384355521 285.507937278578 3.02863518470875 0.00260217016932775 RHPN1 other 9.01447471427585e-06 1 2.5921510734431e-06 6.46371090713547 3.02863518470875 0.303874183834831 36.8433917568396 156.500414843221 0.235420409548106 0.813992476909279 -121.308695281278 199.968045063841 -0.606640402183008 0.544403881225774 TPRG1L other 1 1 1 0.235420409548106 -0.606640402183008 0.756627357880777 -5.6604624277457 9.01351296195117 -0.627997369243298 0.530332952863919 -11.2704971098265 17.9666136912106 -0.627302245349671 0.530787997189894 LRRC43 other 1 1 1 -0.627997369243298 -0.627302245349671 0.000183267441585165 66.133557029248 16.1679199879912 4.0904183765363 5.12730066940939e-05 23.9789003672486 35.2573775216229 0.680110151486526 0.496794849777883 AAED1 other 0.877484510309772 1 0.432026354404435 4.0904183765363 0.680110151486526 2.25275826299257e-08 52.7318252642515 28.0330619100335 1.88105835293639 0.0606286020154334 -53.63748087424 36.0104456213954 -1.48949783732672 0.137077660389991 XKR8 other 0.000151047441533652 1 1 1.88105835293639 -1.48949783732672 2.43493034434655e-70 62.3971665801034 24.5377440460453 2.54290559323687 0.0113373221618794 -296.449430789314 31.5204632472049 -9.40498331082117 2.96494109047653e-19 EYA3 other 2.37746598821997e-66 2.90593876277605e-15 1 2.54290559323687 -9.40498331082117 0.119052401397459 8.54109605102726 11.3277496913978 0.753997597379231 0.45125581250213 -36.6495755557639 24.7397575746443 -1.48140398891079 0.13921797247947 DZIP1L other 1 1 1 0.753997597379231 -1.48140398891079 3.38669631815038e-09 160.296018388862 25.1192196569654 6.38140915911826 4.48138914268738e-10 144.2251631483 54.7774736114484 2.6329283488196 0.00876523623978172 FANCC other 2.35951132485537e-05 1 4.23894599006799e-06 6.38140915911826 2.6329283488196 1.304302356768e-72 -115.866857802172 189.328247886 -0.611989278387761 0.540863121943842 -3012.80425509596 243.189213298367 -12.3887248707844 2.03251067877945e-30 WASF2 other 1.27547727468342e-68 2.00181976752988e-26 1 -0.611989278387761 -12.3887248707844 0.00320215820711602 -31.4274723928051 39.9520465238689 -0.786629850714383 0.431938013590371 -203.429841641589 65.5518115584409 -3.10334431353169 0.00204155286527027 ABHD3 other 1 1 1 -0.786629850714383 -3.10334431353169 0.109464426742243 -2.85637167309299 18.5652049141252 -0.153856188838495 0.877794479762462 -29.6761873412957 23.7520070758607 -1.24941809113285 0.212184044088867 FAM46B other 1 1 1 -0.153856188838495 -1.24941809113285 0.772971985239448 -59.8517024669371 328.77069938075 -0.182046948160738 0.855630104076171 -510.208939123908 718.033821536742 -0.710563936991093 0.477732668852743 CLSTN2 other 1 1 1 -0.182046948160738 -0.710563936991093 0.236607631377721 102.458754241173 116.749880395612 0.877591941798883 0.380651870766291 385.053362652446 226.501625993183 1.70000264220635 0.0898485468864139 COLEC12 other 1 1 1 0.877591941798883 1.70000264220635 0.000246478138758635 -0.210398488006403 17.5207446733633 -0.0120085357060349 0.990424285225871 -48.1450136008762 22.2993978428726 -2.15902751904418 0.0313916339876642 RNF207 other 1 1 1 -0.0120085357060349 -2.15902751904418 1.36659428259451e-21 -127.190836188928 66.6869991006186 -1.90728084790591 0.0571395696341828 -589.630095029499 84.8753835305173 -6.94700949206899 1.36045656669269e-11 GPR153 other 1.18470058358118e-17 1.29705929068481e-07 1 -1.90728084790591 -6.94700949206899 0.252206970183647 1.86097495626405 10.6282672060618 0.175096741565045 0.861084530857313 -10.0599484100091 13.6477306312469 -0.737115105933916 0.461447012869798 RHBDL2 other 1 1 1 0.175096741565045 -0.737115105933916 0.0200976881368035 12.1228926217567 16.4758617046886 0.73579718251136 0.462250691479469 92.5445923782934 33.5290870962503 2.76012860453463 0.00602201103247042 HIST1H2BD other 1 1 1 0.73579718251136 2.76012860453463 6.30054295319572e-06 14.4221785325006 8.080774774873 1.78475194944748 0.0749983145467498 81.3234488168115 16.4447241721383 4.94526073928288 1.08805498430791e-06 HIST1H4H other 0.035730379087573 0.00957814802686252 1 1.78475194944748 4.94526073928288 1.40443293693095e-07 234.413847107012 57.6102261498837 4.06896245290099 5.60181279136573e-05 -246.523411236937 122.411454908202 -2.01389168539666 0.0446318929780556 ZC3H18 essential 0.000896870873524106 1 0.47144856452134 4.06896245290099 -2.01389168539666 0.00953326886344688 8.4418474638228 20.1601578118338 0.41873915584468 0.675612501228384 -108.141027157201 41.9050463653694 -2.58062063013417 0.0101874573129833 ZSCAN12 other 1 1 1 0.41873915584468 -2.58062063013417 0.00139957261919278 129.73445083124 35.6874392967784 3.63529727511022 0.000310640070860472 136.990764006014 75.8294431079162 1.80656428942853 0.0715164317695974 RNF166 other 1 1 1 3.63529727511022 1.80656428942853 0.000676662838934934 -149.280712185644 183.803391260305 -0.812176049430072 0.417131803855601 -632.332403551176 234.867262035591 -2.69229690877631 0.00736817662407107 NBL1 other 1 1 1 -0.812176049430072 -2.69229690877631 0.134424086907104 38.6342189252145 20.25263429509 1.90761450398484 0.0570962782074161 8.81582564191113 43.0345235500417 0.204854728591565 0.837781006283392 SPATA2L other 1 1 1 1.90761450398484 0.204854728591565 0.0260298196059109 175.106055378249 102.597397312362 1.70672999476908 0.0885826447662686 -268.132482245031 218.007694529015 -1.22992210354917 0.219387990934061 ZNF276 other 1 1 1 1.70672999476908 -1.22992210354917 0.649687032086016 0.82076828784898 6.400983898108 0.128225332372978 0.898029775782912 4.90061039562877 8.18608995504272 0.59865093378432 0.549716566789113 CDA other 1 1 1 0.128225332372978 0.59865093378432 0.0612811420347711 2.04146283818432 4.25210868547528 0.480105987214702 0.631392804505241 -22.0860204504815 9.95621735894932 -2.21831441140938 0.0270478691467799 WNT9B other 1 1 1 0.480105987214702 -2.21831441140938 2.93197972682571e-46 39.2757411464313 85.0453049172541 0.461821392546538 0.644438695372124 -915.773640596736 109.206457690578 -8.38570959962332 6.971067615147e-16 CACHD1 other 2.77951678103077e-42 6.78912275039166e-12 1 0.461821392546538 -8.38570959962332 5.2683655685955e-31 356.983076901565 87.1402208659808 4.09665104533755 4.99427936672339e-05 -339.09796346044 111.890965573664 -3.03061075326223 0.00258522282943093 EPB41 other 4.78472960939844e-27 1 0.421067693408449 4.09665104533755 -3.03061075326223 8.08544647485333e-08 94.7646367072656 17.9811484754228 5.27022157882702 2.15387659773546e-07 7.85638153903539 35.5908809216205 0.220741418464381 0.825397826006532 MIS18A other 0.000524745476217981 1 0.00195959692861972 5.27022157882702 0.220741418464381 1.38594691253563e-11 619.049642842478 88.5182971679056 6.99346533596592 1.0135894574008e-11 174.514948273739 186.53228778542 0.935575016774008 0.350009931292598 FBXW5 other 1.04181629415303e-07 1 9.70815982298489e-08 6.99346533596592 0.935575016774008 4.31530086045393e-05 199.890550188995 62.5543864212595 3.19546816178284 0.00149817900769747 -172.092323486866 123.816658390155 -1.38989636551643 0.165274481087182 C21orf59 other 0.223834655631745 1 1 3.19546816178284 -1.38989636551643 0.0512175163632451 -5.52511549768808 165.897076678642 -0.0333044777418878 0.973447129527673 -718.318362966076 328.367407086641 -2.18754464500353 0.0292368199096892 SYNJ1 other 1 1 1 -0.0333044777418878 -2.18754464500353 0.000126040156381978 433.466514957437 118.011416809546 3.67308966095197 0.000269490275436551 -66.2045667202648 235.75034228296 -0.280824901797184 0.778978219496791 PAXBP1 essential 0.616210324551491 1 1 3.67308966095197 -0.280824901797184 0.0465476071287352 133.345420107377 53.8241894582307 2.47742551164392 0.0136122522508648 102.391777723271 107.524097506254 0.952268190089349 0.34148980239134 IFNAR2 other 1 1 1 2.47742551164392 0.952268190089349 0.000118432027398216 98.8570038910517 47.2747417997702 2.09111673861183 0.037094559189732 -351.012380615495 106.754965940516 -3.28801922723744 0.00109045022137941 MRPL10 essential 0.581856550607436 1 1 2.09111673861183 -3.28801922723744 0.00798313956006111 209.846997199833 114.900754748963 1.82633262643323 0.0684854192582494 697.214306801821 227.060822653487 3.0706059224749 0.00227013300311547 IFNGR2 other 1 1 1 1.82633262643323 3.0706059224749 0.00212681762426497 230.127183996992 101.782045196647 2.26098015177801 0.0242537601105768 -302.701750776088 201.136319462808 -1.50495818748468 0.133060551813207 GART other 1 1 1 2.26098015177801 -1.50495818748468 1.01859171783336e-05 147.229880236314 43.9627757464275 3.34896688702096 0.00088158420272347 -154.231317043569 86.8753823457739 -1.77531669938109 0.0765431372383475 DONSON essential 0.0565725840084648 1 1 3.34896688702096 -1.77531669938109 1.34455935064306e-15 -1.56795958670896 843.490724809711 -0.00185889369093263 0.998517670437621 -4947.29402936945 1079.14767204428 -4.58444581546247 5.95778028197744e-06 C1QC other 1.09151328085204e-11 0.0509807258728809 1 -0.00185889369093263 -4.58444581546247 0.0292198621563272 3.27961612762501 2.09037106920579 1.56891576617115 0.117391335166582 -5.3459302584373 4.13073508694939 -1.29418375807424 0.196285457210366 KCNE2 other 1 1 1 1.56891576617115 -1.29418375807424 0.0176486385669399 185.092327175034 68.0257917963351 2.72091396935427 0.00676948265656353 -51.5168593848008 154.857558954025 -0.332672552329818 0.739540633149425 ATP5G1 other 1 1 1 2.72091396935427 -0.332672552329818 0.251092988499515 832.477129681568 548.468892210421 1.51782013803289 0.129782820389915 22.3159825156559 1083.81699810581 0.0205901757904311 0.983581975187056 RCAN1 other 1 1 1 1.51782013803289 0.0205901757904311 0.000546086279427366 257.187751253557 70.5320868290223 3.64639361765957 0.00029791469388185 -111.53449792685 160.563023315874 -0.694646224413883 0.487645340108642 UBE2Z other 1 1 1 3.64639361765957 -0.694646224413883 1.96300325342504e-13 482.619739702306 61.1924776359886 7.88691287470385 2.4925595167529e-14 121.102040011203 139.301836300985 0.869349918328011 0.385131903566797 SNF8 essential 1.53565744515441e-09 1 2.4127976122168e-10 7.88691287470385 0.869349918328011 3.27892694894236e-08 -132.300616937745 192.306570710599 -0.687967220510854 0.491838426027731 1938.55628555403 380.012673724476 5.10129377147974 5.03845045802651e-07 CLIC6 other 0.000217524013792836 0.00448925935810162 1 -0.687967220510854 5.10129377147974 4.86227310957335e-26 70.7138770041472 22.6890016720502 3.1166588123292 0.00194950909779566 -98.2537423986571 29.275094162767 -3.35622293313131 0.000859022401538212 CCDC24 other 4.32693684020933e-22 1 1 3.1166588123292 -3.35622293313131 0.585441013454828 240.481024490549 335.389877713931 0.717019327266835 0.47374522324641 -247.963598002303 662.756367082218 -0.374139895621014 0.708481703733432 CBR1 other 1 1 1 0.717019327266835 -0.374139895621014 0.000219632843690708 112.108556116408 28.7395680122818 3.90084346669714 0.000110949851394983 21.5332460896118 56.7916116525691 0.379162440772848 0.704751403811607 CBR3 other 1 1 0.919774268064408 3.90084346669714 0.379162440772848 0.464471399990801 -35.7504871033581 30.7920754610565 -1.16102882212577 0.246263988397783 -17.1032195212467 49.3505633487288 -0.346565841617435 0.729084323210799 GJD2 other 1 1 1 -1.16102882212577 -0.346565841617435 0.607501572173655 -41.2387734273514 92.8302401827895 -0.444238572970933 0.657090011965925 -146.21627389126 148.779339496373 -0.982772704773465 0.326263100359849 ACTC1 other 1 1 1 -0.444238572970933 -0.982772704773465 0.00323960410590079 121.361220165764 53.4110873657389 2.27221024980691 0.0235589172483296 -141.70655841323 105.544444172585 -1.34262451732195 0.180090579822142 MORC3 other 1 1 1 2.27221024980691 -1.34262451732195 0.00626916315063698 86.4022558733719 28.8627077179706 2.99356029647821 0.00291387049088418 13.1534955354363 57.034945245527 0.230621691294914 0.817716640389156 CHAF1B essential 1 1 1 2.99356029647821 0.230621691294914 0.0128989501554595 106.285692029664 48.7756648683318 2.17907213190386 0.0298597655420223 -86.8677901521406 96.3844904041139 -0.901263157463691 0.367944850808133 SIM2 other 1 1 1 2.17907213190386 -0.901263157463691 0.0217250450450218 9.5423132049613 41.4821332477687 0.23003429326949 0.818172759795653 -197.843077032644 81.9719071950086 -2.4135473213034 0.0162084589473001 HLCS other 1 1 1 0.23003429326949 -2.4135473213034 0.888672039156782 -11.155266781842 30.4659774715345 -0.366154894989494 0.714426692166409 -21.5643055659877 44.7408196504336 -0.481982800817525 0.630059461750288 SCUBE1 other 1 1 1 -0.366154894989494 -0.481982800817525 0.0231258871738702 0.05582699963808 40.0742808720489 0.00139308799617209 0.998889112656698 253.378393051032 93.0519961423877 2.72297643849911 0.00672867427253817 ARHGAP27 other 1 1 1 0.00139308799617209 2.72297643849911 8.07348858369461e-05 48.3297446962616 58.9388743460462 0.81999775585303 0.412664407541968 -313.25115429882 102.255214680556 -3.06342473855648 0.00232350226710913 ADPGK other 0.404562512928937 1 1 0.81999775585303 -3.06342473855648 3.90371896496347e-11 143.852614674244 166.2199586262 0.865435269405548 0.38727369586657 -643.1269048452 212.398837205981 -3.02792102492306 0.00260786117586266 ATP13A2 other 2.90358616613983e-07 1 1 0.865435269405548 -3.02792102492306 1.27408804169036e-38 -336.140603280973 293.069180139387 -1.14696674389679 0.252021515322279 -3273.56810621067 374.489042092111 -8.74142561801712 4.95619329531547e-17 ALDH4A1 other 1.1850292875762e-34 4.84071399153462e-13 1 -1.14696674389679 -8.74142561801712 0.418175766777205 34.8779491628551 54.9246401480007 0.635014614003341 0.525751980723273 -40.3122450819116 83.045016880038 -0.485426418061235 0.627617726810375 STARD9 other 1 1 1 0.635014614003341 -0.485426418061235 6.71223588717016e-08 50.6246591702924 63.2138395589613 0.800847718213247 0.423655992082702 -377.547964035424 95.5781295804637 -3.95015016189012 9.10662982324291e-05 UBR1 other 0.000437033678613649 0.727437590280644 1 0.800847718213247 -3.95015016189012 0.000752031266545114 247.299869968254 169.969836385826 1.45496327599499 0.146397344580475 -1131.52275904979 391.718039031915 -2.88861539756048 0.00406175123053872 AMFR other 1 1 1 1.45496327599499 -2.88861539756048 1.46904349743565e-54 86.1048786720398 21.7697681933109 3.9552501389747 8.91499763096221e-05 -175.572708719659 28.0890284628904 -6.25057961515527 9.71150288334132e-10 MED8 essential 1.4129260358336e-50 9.09579360053748e-06 0.742797602611772 3.9552501389747 -6.25057961515527 1.26795745953024e-05 35.8017741085547 17.7083571221725 2.02174452782678 0.0438102884999801 -65.3474442297553 28.1504271807135 -2.32136598888014 0.0207251685432841 RGL4 other 0.0697630194233538 1 1 2.02174452782678 -2.32136598888014 0.000262465756958644 176.665586034914 65.6753647703168 2.68998256275786 0.00741924825668103 -323.758437240231 159.048349225477 -2.03559759542836 0.0423935247771896 RSPRY1 other 1 1 1 2.68998256275786 -2.03559759542836 1.91197189831774e-08 -0.395716140572581 3.06524140067572 -0.12909787153643 0.897339465778751 -13.3683633933843 3.95501009402874 -3.3801085396894 0.000789471239485917 CCDC17 other 0.000128752187632716 1 1 -0.12909787153643 -3.3801085396894 2.58145407694131e-105 154.196976210949 53.6481893351423 2.87422517184457 0.00424738702868415 -929.555674978502 69.2210180575268 -13.428806756439 1.12539659194819e-34 GPBP1L1 other 2.54350670201027e-101 1.10874072238736e-30 1 2.87422517184457 -13.428806756439 1.19482318017234e-13 347.821488612149 50.5360190815193 6.88264518918834 2.04289090941279e-11 -157.953809692075 116.635652152289 -1.35424980936222 0.176354934807329 NAE1 essential 9.39728431205548e-10 1 1.95198226394392e-07 6.88264518918834 -1.35424980936222 3.73836901650114e-79 101.847787538805 19.6219380937651 5.19050600670112 3.21579592921805e-07 -203.829250795097 25.3177329551077 -8.05084922716101 7.82694877683636e-15 TMEM69 other 3.66920918969587e-75 7.59292300840895e-11 0.00291640532820785 5.19050600670112 -8.05084922716101 0.100690611825576 1.09299791400723 6.25230524110409 0.174815187656164 0.861305632518735 30.2586527185363 14.6396328455965 2.06689969876108 0.0393306539110568 ADGRG5 other 1 1 1 0.174815187656164 2.06689969876108 0.54146583840978 -11.1800014755948 18.9484231553665 -0.590022788910982 0.555479630040904 29.5556281641841 44.0517928196996 0.670929064911226 0.502619361588804 DRC7 other 1 1 1 -0.590022788910982 0.670929064911226 1.38788878120343e-33 -269.0473057101 215.428656918195 -1.24889283328849 0.212371338750827 -2274.12557679747 276.631385235963 -8.22077934091847 2.31407058243544e-15 EFCAB14 other 1.27283280124166e-29 2.24950801318549e-11 1 -1.24889283328849 -8.22077934091847 0.894259648544742 22.9314122491456 51.4730345468547 0.445503406803646 0.656177118193431 31.4163984138706 80.0204833454199 0.392604457014553 0.694803511558467 SPON2 other 1 1 1 0.445503406803646 0.392604457014553 0.0112383773006093 59.156057233707 46.7436381057927 1.26554242739561 0.206351272363646 -173.521598909832 92.8450928153943 -1.86893667342062 0.0623003440210165 CHCHD6 other 1 1 1 1.26554242739561 -1.86893667342062 4.08638248641544e-12 360.801058470793 171.29047927381 2.1063696009283 0.0357431907646419 -1197.96497165937 266.289855739552 -4.49872552723546 8.77887453061435e-06 CTBP1 other 3.10851115741622e-08 0.0745326447649158 1 2.1063696009283 -4.49872552723546 0.698261768470775 3.05119446615772 4.79428541045413 0.636423200734873 0.524833061108472 8.28707520871473 11.0650703323209 0.748940129599387 0.45429529794095 LRRC36 other 1 1 1 0.636423200734873 0.748940129599387 0.545792714167889 -238.700510766791 369.894510102351 -0.645320501514722 0.519057397824673 518.079245592801 853.705697390719 0.606859304296865 0.544258719702923 TPPP3 other 1 1 1 -0.645320501514722 0.606859304296865 0.0189588085084458 16.5679255586851 26.6094866838277 0.622632287332114 0.533850206673909 172.060913669345 61.4139160387658 2.80166002703258 0.0053093634168714 ZDHHC1 other 1 1 1 0.622632287332114 2.80166002703258 0.0339323585143779 286.861900223796 144.169737413496 1.98975114590826 0.0472397132438281 -292.586364561131 332.73953210922 -0.879325527407098 0.379706957452698 ATP6V0D1 other 1 1 1 1.98975114590826 -0.879325527407098 0.0236728479839199 -35.6875851851838 50.239954186085 -0.710342709569352 0.477870539794426 -211.34548148148 81.6956461314281 -2.58698586141882 0.0100040164897506 ZFYVE28 other 1 1 1 -0.710342709569352 -2.58698586141882 0.449946807331924 -41.1607683988482 35.1694700687603 -1.1703550925952 0.242494489068704 2.89573718532205 81.1701070221486 0.035674921366457 0.971557820184781 CARMIL2 other 1 1 1 -1.1703550925952 0.035674921366457 0.235471542513417 18.6293567764941 11.065284509495 1.68358588163807 0.0929742442980823 8.98337420181516 25.538352614077 0.351760128680479 0.725187327599946 C16orf86 other 1 1 1 1.68358588163807 0.351760128680479 2.39692604570519e-07 256.053412589813 151.998223283515 1.68458161587987 0.0927833169563349 -887.452873759833 252.159669058344 -3.51940846477911 0.000477891762148746 RGS12 other 0.00151150156442169 1 1 1.68458161587987 -3.51940846477911 2.97117895157492e-05 192.727034233154 60.2181802700635 3.20047921356675 0.00147179135496592 -276.241188291266 138.981796644751 -1.98760697415189 0.0474774358500131 PSKH1 other 0.157442772643955 1 1 3.20047921356675 -1.98760697415189 0.507370999974214 -191.090676241899 563.639831071588 -0.33902975926772 0.734751288990926 453.764005611348 400.881625311115 1.13191520129961 0.258295102822248 ABR other 1 1 1 -0.33902975926772 1.13191520129961 0.904445154315163 -4.9113698462638 20.3742452820527 -0.241057755920419 0.809623931094899 -0.899978744533614 25.1053690477416 -0.0358480587487948 0.971419956423169 LYPD5 other 1 1 1 -0.241057755920419 -0.0358480587487948 1.28726268708588e-08 82.2072387066267 29.6532917442635 2.77228037330897 0.00580442554308262 -134.839419841098 47.5195815437617 -2.83755486602763 0.00475765340592144 CCDC117 other 8.75209900949691e-05 1 1 2.77228037330897 -2.83755486602763 5.11756641651289e-62 47.6960172993467 6.47694334246212 7.36397012872677 8.98778855990301e-13 -19.535053605547 8.07453758595291 -2.41934022816757 0.0159569685711083 ZNF230 other 4.9640394240175e-58 1 8.6552403831866e-09 7.36397012872677 -2.41934022816757 3.56528217194198e-08 232.5678050057 39.973661873365 5.81802602279636 1.15749769035903e-08 89.1115285643962 46.7054058586251 1.90794891782189 0.0570574470769427 CCDC107 other 0.000235879068495681 1 0.000107554685388161 5.81802602279636 1.90794891782189 3.82740015544405e-44 31.6388168905608 6.33296161016229 4.99589589170903 8.4913410569464e-07 -22.6662702938308 7.8950415107713 -2.87095011000347 0.00429172721224155 ZNF222 other 3.61038656663037e-40 1 0.00763371561019482 4.99589589170903 -2.87095011000347 0.000492319108676432 146.823205774183 40.8183931656826 3.59698641683969 0.000358872124103404 25.1437482989398 48.0429837278067 0.523359424164716 0.600990651961928 NPR2 other 1 1 1 3.59698641683969 0.523359424164716 0.000985388219265836 4.00501832271317 1.22418886543071 3.27156898400974 0.00115448299436668 -5.80815068972759 4.87895954483862 -1.19044862666917 0.234517862578939 ZNF890P other 1 1 1 3.27156898400974 -1.19044862666917 1.36852197020627e-10 21.9054489683341 6.57052113254212 3.33389825958279 0.000929658158275008 0.106172351377471 8.19251725462563 0.0129596738191212 0.989665907288518 ZNF221 other 1.00326345635822e-06 1 1 3.33389825958279 0.0129596738191212 3.58526169688575e-05 18.3709897724935 8.51909188853116 2.15644930385426 0.0315947489544817 42.2082441759259 10.8462853811352 3.89149304971617 0.000115201989011295 ZNF233 other 0.187939418150751 0.910786925123295 1 2.15644930385426 3.89149304971617 1.94582408026286e-40 89.7225591593811 17.5023816235182 5.1263057273771 4.45050764721525e-07 -59.6420892248364 22.2835753413791 -2.67650447969564 0.00771989062555475 ZNF235 other 1.81817802059761e-36 1 0.00402281386231787 5.1263057273771 -2.67650447969564 2.81917095291448e-06 303.860049956705 59.8727468127379 5.07509787227699 5.75504330208395e-07 230.793563352729 70.5138282292257 3.27302557737281 0.00114909232391415 GNE other 0.0164949692455026 1 0.00519335107580055 5.07509787227699 3.27302557737281 1.11861812985567e-33 -746.904107383447 316.912320061272 -2.35681625516812 0.0188727002197612 -3146.96513342428 384.713132322578 -8.18003044093016 3.12003053472496e-15 ARHGAP35 other 1.02610841051661e-29 3.0311096644853e-11 1 -2.35681625516812 -8.18003044093016 2.17454188032465e-67 88.8233527807317 64.8722893332765 1.36920330226683 0.171637402229726 -823.87337261254 82.8929248439215 -9.93900714884659 3.99016031859761e-21 DFFA other 2.11887360818834e-63 3.91873644889472e-17 1 1.36920330226683 -9.93900714884659 7.13661063696245e-18 154.028995603171 39.6997854003515 3.87984453945705 0.000120627206419642 -63.7804499322273 50.9995472025261 -1.25060816087144 0.211746666521128 CCDC28B other 5.96121086505474e-14 1 0.99806950591612 3.87984453945705 -1.25060816087144 9.35848181058863e-52 46.0798777818602 7.26364690623202 6.34390387868729 5.60393384197361e-10 -32.2494519346223 9.3311008994417 -3.45612508986499 0.000601599089455533 IQCC other 8.96355387818179e-48 1 5.29571748066506e-06 6.34390387868729 -3.45612508986499 3.40426426720304e-44 82.5596635309297 13.3710101133644 6.17452704253145 1.51803795135842e-09 -45.529813086412 17.1768047243888 -2.65065673255083 0.00832524681847591 TMEM234 other 3.21158290967935e-40 1 1.42801830084287e-05 6.17452704253145 -2.65065673255083 2.75472238582713e-65 191.838599569001 87.078465522103 2.20305443393817 0.0281132830008077 -1022.13196592993 111.910363278695 -9.13348805225908 2.50558330844418e-18 BSDC1 other 2.6803448814098e-61 2.45346717562854e-14 1 2.20305443393817 -9.13348805225908 4.32441434910599e-07 53.2380256285384 17.0370056295447 3.12484639532053 0.00189749273506837 4.63910400320631 21.886253641713 0.21196428037207 0.832233725421876 ZBTB8A other 0.00268632619366464 1 1 3.12484639532053 0.21196428037207 4.07660064203657e-19 232.583106347173 40.2064249070613 5.78472487630517 1.38586570134191e-08 17.8685877455467 53.3513603620133 0.334922814044482 0.737844014042765 ATAD3B other 3.4557343642544e-15 1 0.000128649913055569 5.78472487630517 0.334922814044482 1.01098062066889e-64 798.3631672629 93.1518528479007 8.57055595626719 1.78139319689731e-16 -440.449985039287 123.542182104644 -3.56517893350963 0.00040363159254351 SSU72 essential 9.83077555538432e-61 1 1.73240488398264e-12 8.57055595626719 -3.56517893350963 4.04335892005779e-67 317.534036952502 39.2379739532652 8.09251867414725 5.89955368453915e-15 -232.474634723357 52.117209858261 -4.460611674255 1.04182502187307e-05 UBE2J2 other 3.9390402599203e-63 0.0881904881015557 5.72020725252916e-11 8.09251867414725 -4.460611674255 3.0915188194447e-75 128.884831723425 48.506021351809 2.65708932894408 0.00817123677614083 -617.575723133022 62.3383340317039 -9.90683714484472 5.2945003954707e-21 ZNF362 other 3.02783353176414e-71 5.19919938835223e-17 1 2.65708932894408 -9.90683714484472 4.57927776658912e-05 -75.1855789917701 47.6222411020228 -1.57879128012261 0.115109140453781 57.2904048203572 61.2025288906842 0.936079045404895 0.349750674749971 FNDC5 other 0.236748660532657 1 1 -1.57879128012261 0.936079045404895 1.0615504792482e-07 25.4578611898017 10.3170281786461 2.46755759012985 0.0139851592931893 -69.0463881019836 19.9754968187984 -3.45655423383542 0.000600541826618175 CCDC58 other 0.000682895423300365 1 1 2.46755759012985 -3.45655423383542 0.199821701990431 -389.184962228524 225.569629890245 -1.72534291259816 0.0851710366179549 -547.891288951843 436.740633665831 -1.25450037555026 0.210329212867828 KALRN other 1 1 1 -1.72534291259816 -1.25450037555026 0.355764594276194 -116.091115680121 141.213148620487 -0.822098485971146 0.411468140364043 -402.388594307974 282.083462000495 -1.42648771911083 0.154439999248457 ABCG1 other 1 1 1 -0.822098485971146 -1.42648771911083 0.780101428245011 -2.58969087039646 17.2989242549595 -0.149702422660993 0.881068304377388 -23.5418605490028 34.5558504317308 -0.68126989366135 0.496060757023307 TMPRSS3 other 1 1 1 -0.149702422660993 -0.68126989366135 0.0579799446949854 267.476012697042 120.623678700973 2.21744201120011 0.0271054644842717 50.2132164628649 240.954508978844 0.208392931411272 0.835019045884593 RSPH1 other 1 1 1 2.21744201120011 0.208392931411272 0.00217547952855476 56.4223568877833 26.9255828420912 2.09549249940772 0.0367007840514392 -84.2966940807275 53.7857961434641 -1.56726682739586 0.117774477712015 SLC37A1 other 1 1 1 2.09549249940772 -1.56726682739586 6.9775301848722e-05 107.903527756737 67.7085650203385 1.59364664905134 0.111736535447633 -398.214289579052 135.25274816549 -2.94422327812379 0.00340995293827524 PDE9A other 0.352644375543441 1 1 1.59364664905134 -2.94422327812379 1.5967205061138e-05 48.8712621289189 13.9679374831281 3.49881735853634 0.000515144908297107 -35.5726021714821 27.9019638095912 -1.27491392413226 0.203015586573184 WDR4 essential 0.0869733659680186 1 1 3.49881735853634 -1.27491392413226 3.53018815363566e-08 158.684016881291 48.3650596760194 3.28096394265323 0.00111722206777831 -284.614246293693 96.6126993594475 -2.94592996759966 0.0033915632994397 NDUFV3 other 0.000233663153889144 1 1 3.28096394265323 -2.94592996759966 6.69501251859252e-05 70.7279875915314 25.7044647926922 2.75158374865831 0.00617686440106075 -94.3220069978001 51.3465246574108 -1.83696964160917 0.0668917441514905 PKNOX1 other 0.339102384066711 1 1 2.75158374865831 -1.83696964160917 0.00388842211550164 -176.652653031782 273.112266459726 -0.646813324504528 0.518091571586493 -1758.05701944235 545.561474907757 -3.22247281067564 0.00136576626600431 CBS other 1 1 1 -0.646813324504528 -3.22247281067564 1.85587869149566e-05 181.48344335029 57.632786436487 3.1489618075345 0.00175061668668946 -195.643058110593 115.125652827352 -1.69938717658339 0.0899562805021807 U2AF1 essential 0.10034736084917 1 1 3.1489618075345 -1.69938717658339 0.00838320514578172 1.7303138291761 15.7820918771327 0.109637799769955 0.912746844912745 -83.4239485655158 31.0128832919998 -2.68997718722387 0.00741873576197197 HSF2BP other 1 1 1 0.109637799769955 -2.68997718722387 0.00303024200329734 168.169214852284 67.1657302886539 2.50379492829981 0.0126496737078939 -117.130351600347 131.985225461911 -0.887450479327693 0.375323459424395 RRP1B other 1 1 1 2.50379492829981 -0.887450479327693 0.12515677493064 160.098114725833 111.90401920323 1.43067349918038 0.153236833669917 -135.002914949173 219.89900416712 -0.613931452125052 0.539579349243482 CSTB other 1 1 1 1.43067349918038 -0.613931452125052 6.33032330768367e-07 263.414243016443 67.7265130761754 3.88938144091617 0.000116099600425732 -201.41656676465 133.087201757384 -1.51341800041622 0.130894732919017 RRP1 essential 0.00389504793121776 1 0.961536890725915 3.88938144091617 -1.51341800041622 3.03184929710283e-06 -231.511265662718 225.026263443373 -1.02881886816281 0.30413259553388 -2168.94250570671 442.191903337977 -4.9049801439918 1.31941020350363e-06 AGPAT3 other 0.0176938724978921 0.0115923380479829 1 -1.02881886816281 -4.9049801439918 0.0931374514660912 -12.4375215542011 57.3758880877582 -0.216772619452575 0.828486481191003 -227.758363030231 112.74752009388 -2.02007425831261 0.0439839593985383 TRAPPC10 other 1 1 1 -0.216772619452575 -2.02007425831261 0.573463829186902 -7.42665823657896 7.61416647321749 -0.9753737671355 0.32991326682677 -12.1862529354769 14.9623546763088 -0.814460905326112 0.41582355141594 AIRE other 1 1 1 -0.9753737671355 -0.814460905326112 0.000467996489949713 184.194735027019 97.7867441475819 1.88363705768778 0.0602763023511261 -418.299952375476 192.157599091647 -2.17685875735767 0.0300244657179608 C21orf2 other 1 1 1 1.88363705768778 -2.17685875735767 0.742138054399202 1.3849867800896 17.9914815699147 0.0769801405574942 0.938674494730244 -22.6965578966383 35.3544842167845 -0.641971121894153 0.521227768507461 LRRC3 other 1 1 1 0.0769801405574942 -0.641971121894153 3.27583862058568e-05 -315.919186113358 406.026951587157 -0.778074423085543 0.436945232743565 2898.21293087873 797.870558669353 3.63243498508356 0.000314004462349451 ITGB2 other 0.17260393691866 1 1 -0.778074423085543 3.63243498508356 6.16569961417485e-05 48.9803425681118 14.7765635329424 3.31473163289397 0.0009935541593644 -30.8413692871109 29.0369517470596 -1.06214211311743 0.288756447950457 FAM207A other 0.313772453365358 1 1 3.31473163289397 -1.06214211311743 0.000310839201522451 376.707875495282 278.363398527125 1.35329528770132 0.176659328593024 -1741.1419774519 586.567503816155 -2.96835737766614 0.00315818157910891 RALGDS other 1 1 1 1.35329528770132 -2.96835737766614 0.230316117535516 9.3607102127494 6.2262197719841 1.5034339543987 0.133449488812076 0.171674072908949 11.8506817418171 0.0144864301184605 0.988448516535935 FTCD other 1 1 1 1.5034339543987 0.0144864301184605 0.0124756630493163 46.8368594911324 30.3672832146789 1.54234605578718 0.123713319585693 -84.5631169137608 57.7995994230866 -1.46303984383643 0.144175321435679 SPATC1L other 1 1 1 1.54234605578718 -1.46303984383643 0.000258409915852149 370.521156946792 254.68438177725 1.45482480849907 0.146435667677767 -1275.87870148256 484.753777345676 -2.63201394421057 0.00878848559536822 LSS other 1 1 1 1.45482480849907 -2.63201394421057 8.16223904440267e-06 400.388156818205 84.8107832848389 4.7209581295045 3.1643477091341e-06 129.392656726762 174.990239520558 0.739427850840564 0.460043331851334 VAV2 other 0.0458146477562322 1 0.027985491139582 4.7209581295045 0.739427850840564 1.73807724301243e-05 298.303059499008 133.292674907033 2.23795538432298 0.0257270334737627 -646.249931180929 253.702748487364 -2.54727209316424 0.0111985225825397 MCM3AP essential 0.0943254519782847 1 1 2.23795538432298 -2.54727209316424 2.86199620078575e-07 121.954933343822 23.1389693909366 5.27054300834985 2.14169535132393e-07 42.7509143104339 44.0415809476402 0.970694361795487 0.332237452650677 C21orf58 other 0.00179790601333361 1 0.00194872860016964 5.27054300834985 0.970694361795487 8.52607128694761e-07 350.985960910777 93.3863498566665 3.7584289507994 0.000194195291302476 -267.533092138894 177.747004074781 -1.50513418513844 0.133011997174321 PCNT other 0.00518981959236501 1 1 3.7584289507994 -1.50513418513844 0.000234787019013744 250.207834396413 90.6882069676759 2.75898976021871 0.00604266870662342 -228.58153320845 172.621562082362 -1.32417717955413 0.186139550448989 DIP2A other 1 1 1 2.75898976021871 -1.32417717955413 0.118046157856093 2713.90632632252 1705.07075051792 1.59166786803313 0.112185750043549 -1222.54223081118 3245.53749883111 -0.376684056570439 0.706592083843111 S100B other 1 1 1 1.59166786803313 -0.376684056570439 8.40615977539401e-08 699.601154767264 144.65127423752 4.83646727935841 1.8372685525213e-06 -122.975849477153 275.338213765598 -0.446635604245786 0.655360450220604 PRMT2 other 0.000544971338238793 1 0.0163663882658597 4.83646727935841 -0.446635604245786 5.70100384774268e-14 12.4066031873982 3.78697334837738 3.27612635370515 0.00113626107906802 -2.48603624028087 4.73603527186807 -0.524919283234198 0.599905495648102 CLDND2 other 4.50629953051704e-10 1 1 3.27612635370515 -0.524919283234198 0.00889685835586175 42.5761038011 34.8751574397155 1.22081466943042 0.222812981961875 -149.537784793677 71.9579741787854 -2.07812666351805 0.0382794870324381 ADAMTS13 other 1 1 1 1.22081466943042 -2.07812666351805 8.15773804561467e-08 364.609672637669 67.7447747535956 5.38210768230973 1.20215388461588e-07 29.1780471840686 139.777913860125 0.208745762318837 0.83474375518444 CACFD1 other 0.000529192467019023 1 0.00109864843515046 5.38210768230973 0.208745762318837 0.00462251966776836 76.7341251889003 27.7629445116864 2.76390442507279 0.00595229948949786 -28.4091644127016 57.283332634477 -0.495941194517776 0.620184658980907 SLC2A6 other 1 1 1 2.76390442507279 -0.495941194517776 1.81465323191308e-54 47.320151919611 11.6955057172978 4.04601161022254 6.16962500332178e-05 -106.022233925718 16.2047836180955 -6.54265039412961 1.70935921235163e-10 ZNF761 other 1.74515201313081e-50 1.61397696830241e-06 0.518186804028996 4.04601161022254 -6.54265039412961 0.148330005995394 -12.3570280390022 19.006265567927 -0.650155497135354 0.515932639451573 -76.479825008903 39.2156614442852 -1.95023677255986 0.051785429721229 C9orf116 other 1 1 1 -0.650155497135354 -1.95023677255986 0.00235025695354227 472.178403767204 191.583223309349 2.46461248334244 0.0140998776108619 -492.519636886463 395.302866247396 -1.245929839978 0.213457694976209 GPSM1 other 1 1 1 2.46461248334244 -1.245929839978 4.95248196768156e-65 72.1180041576258 10.7875454098092 6.68530248707444 7.10391266058756e-11 -82.2536587236684 14.7262294735334 -5.58552064338655 4.1176906021285e-08 C19orf47 other 4.81727920996386e-61 0.000376727513188737 6.76647680920965e-07 6.68530248707444 -5.58552064338655 0.0554880814239221 -9.46829647849901 9.41821571350283 -1.00531743660579 0.315304190444618 5.40442921050582 12.8569383079644 0.420351181677365 0.674436968264739 HIPK4 other 1 1 1 -1.00531743660579 0.420351181677365 0.600821382147708 24.7963213668838 28.827466514761 0.860163044650038 0.390170816180334 -11.49799262406 63.7166043936434 -0.180455200547489 0.856878875689207 CFAP157 other 1 1 1 0.860163044650038 -0.180455200547489 1.747973984355e-08 108.53137478608 17.8645007731278 6.0752537204586 2.69086322153874e-09 66.5989731888192 39.4851778760662 1.68668287117399 0.0923763959607649 TOR2A other 0.000117970764204119 1 2.52537513341411e-05 6.0752537204586 1.68668287117399 0.0029273656616868 104.50574525303 148.888330204155 0.701906892969602 0.483110032619823 -948.06564257192 329.08180734749 -2.88094212868724 0.0041595851246609 ST6GALNAC6 other 1 1 1 0.701906892969602 -2.88094212868724 2.69017308347424e-45 211.808582960306 43.9418926482853 4.82019708745002 1.98679726067811e-06 -288.720976846927 60.0189252335247 -4.8104989505153 2.08053018826924e-06 SHKBP1 other 2.54382766773324e-41 0.0181484648322726 0.0176785220255138 4.82019708745002 -4.8104989505153 0.00031903383895418 74.2140472990257 21.2951292689562 3.48502450310147 0.000542032365967047 106.444664285516 26.3335096816074 4.04217537170376 6.26296997532338e-05 RDH13 other 1 0.505609566107857 1 3.48502450310147 4.04217537170376 1.01850200685653e-08 496.633863965261 119.736063486613 4.14773836306042 4.0357593883146e-05 -736.005788712019 264.649527384663 -2.78105839063997 0.00565247065477197 ZER1 other 6.94822069077522e-05 1 0.341586674626947 4.14773836306042 -2.78105839063997 0.0403126421495659 42.31376919845 23.7437448586634 1.7821017472318 0.0754268793607542 122.726623406937 52.4801857703452 2.33853256434709 0.0198096619500512 ZDHHC12 other 1 1 1 1.7821017472318 2.33853256434709 0.00529551606041966 47.2778348349758 17.020132125722 2.77775956647987 0.00570914861773255 97.590775407311 37.6191582713964 2.59417753856322 0.00980031482400184 PKN3 other 1 1 1 2.77775956647987 2.59417753856322 0.248058429111756 -12.2527046980115 85.9678785341675 -0.142526544878524 0.886730256256974 97.2871090021565 117.420970360235 0.828532660764856 0.407824309878604 SPTBN4 other 1 1 1 -0.142526544878524 0.828532660764856 0.774910470242899 -87.8681535600951 218.181158183274 -0.40273025540677 0.687344972481358 -24.2704226484895 269.982858586832 -0.0898961614656866 0.928411202659083 BRSK1 other 1 1 1 -0.40273025540677 -0.0898961614656866 0.00953108996786426 66.5192465192462 24.1448136035285 2.75501180549703 0.00611419102936347 -7.03690622440656 50.8788465258179 -0.138307110025298 0.890061414269918 PLPP7 other 1 1 1 2.75501180549703 -0.138307110025298 1.51239341877106e-10 135.795749765125 20.7259079483172 6.55198074331654 1.59691933521724e-10 27.0222264204892 43.6736444298841 0.61873074192084 0.536415396602566 MED27 other 1.10692074319854e-06 1 1.51691367652285e-06 6.55198074331654 0.61873074192084 1.13956146529041e-16 119.267092406687 30.2929583572413 3.93712264745437 9.60045751677636e-05 -32.4844827643963 39.2114046374986 -0.828444761535799 0.407872968734696 DEDD2 other 9.39454471985416e-13 1 0.79847005167029 3.93712264745437 -0.828444761535799 0.686319342547492 4.51169492339465 9.18802099123092 0.491040989969508 0.623644522881568 -10.943366472952 19.4568947995706 -0.562441570748152 0.574104259125453 NEK8 other 1 1 1 0.491040989969508 -0.562441570748152 0.599775533840791 -23.6871908169635 23.859626062964 -0.992772927557814 0.321371264934335 -3.61285080767806 50.5260310906179 -0.0715047418072172 0.943028838259222 TLCD1 other 1 1 1 -0.992772927557814 -0.0715047418072172 0.0142465310052359 29.1843346651236 47.2867482279831 0.61717787242247 0.537438106644033 -147.002296404168 76.0041440897611 -1.93413527860478 0.0537402998856484 ANO10 other 1 1 1 0.61717787242247 -1.93413527860478 0.995177001390666 1.19277108433805 25.4138686873059 0.046933865088153 0.962587378012416 -1.66048884533284 40.4693530293174 -0.0410307731910101 0.967290102145943 CCR5 other 1 1 1 0.046933865088153 -0.0410307731910101 0.919502748333507 12.8527448158738 37.2495150388328 0.345044621452781 0.730226835935485 2.29899561207091 57.9822744796454 0.0396499729047016 0.968390293586351 NBEAL2 other 1 1 1 0.345044621452781 0.0396499729047016 3.75102968176308e-08 315.295878647763 81.8585010942842 3.85171820193246 0.000134845211177265 -152.627123192337 127.420238196203 -1.19782481458965 0.231634494759044 CCDC12 other 0.000247905551667722 1 1 3.85171820193246 -1.19782481458965 0.00272687673836632 -37.8496072094178 33.4355517383755 -1.13201682764445 0.258248134334451 -170.16536719432 52.0454920353138 -3.26955055163779 0.001162350933194 PTH1R other 1 1 1 -1.13201682764445 -3.26955055163779 0.00383560747011612 -6.64709223429133 12.2934483570207 -0.540702009822592 0.588988475948949 -57.2116949225392 19.3476594261572 -2.95703442273702 0.00327449791425122 MYL3 other 1 1 1 -0.540702009822592 -2.95703442273702 0.527599291401422 6.29674429800819 9.21983040327349 0.682956629633072 0.494995318514327 -9.6141702272771 18.6515667182891 -0.515461803959331 0.606490418734918 FGFR4 other 1 1 1 0.682956629633072 -0.515461803959331 0.157837649712677 -14.1621532165853 15.94222197111 -0.888342493427172 0.374844126741827 37.1516017732841 32.2508553548187 1.15195709895282 0.249967077343843 HK3 other 1 1 1 -0.888342493427172 1.15195709895282 4.34539421444153e-09 45.4810522688536 7.67189274657972 5.92827008551833 6.22111776466761e-09 -9.31546024344731 24.3883745562631 -0.381963144856452 0.702674372900645 LY6K other 3.01179273002942e-05 1 5.80803554509369e-05 5.92827008551833 -0.381963144856452 0.714608204315743 -37.2773024589969 135.653831254463 -0.274797269743685 0.783601862415149 -353.403398701735 431.233406919157 -0.819517674260305 0.412937847227823 LY6E other 1 1 1 -0.274797269743685 -0.819517674260305 2.65457070587184e-18 1243.46005215165 134.951944175427 9.21409513400743 1.36973266629416e-18 536.48763323435 374.397579899589 1.43293563323308 0.152597820647825 VPS28 essential 2.23037030707352e-14 1 1.33727000210299e-14 9.21409513400743 1.43293563323308 6.03392552704669e-10 140.876883378162 21.8100171211881 6.45927431397119 2.83228508251261e-10 49.0494507497067 59.1703540199309 0.828953139830546 0.407587639982581 TONSL essential 4.33537549118305e-06 1 2.6847230297137e-06 6.45927431397119 0.828953139830546 2.29001454416515e-08 201.065837142003 34.3890140015793 5.84680436411375 9.87853521220264e-09 67.1218094037091 93.297044269306 0.719441970851285 0.472256754939228 RECQL4 ts 0.000153476774749948 1 9.19790413608188e-05 5.84680436411375 0.719441970851285 1.35538100454729e-30 492.837980275098 45.9492472694205 10.7257030215397 5.82640427605636e-24 -294.036107648686 124.659839227712 -2.35870757952431 0.0187821080806848 LRRC14 other 1.22919503302393e-26 1 5.71395467352847e-20 10.7257030215397 -2.35870757952431 4.33148634764359e-15 428.078877736228 51.4864374344585 8.3144008221809 1.20516230144801e-15 234.378738510209 139.682179674326 1.67794302076808 0.0940797970896849 PPP1R16A other 3.48857910439215e-11 1 1.16985104601558e-11 8.3144008221809 1.67794302076808 0.00010086396169648 184.147426505428 42.4710604324039 4.3358330267857 1.80793504352549e-05 188.930719868989 115.223553811237 1.63968835901817 0.101796245761465 FOXH1 other 0.500184386052846 1 0.155355858290146 4.3358330267857 1.63968835901817 0.00933249332894167 125.48411928719 326.626672379124 0.384182095029695 0.701031214666789 -1704.19473067443 660.813002040926 -2.57893643952375 0.0102380030978355 MRNIP other 1 1 1 0.384182095029695 -2.57893643952375 0.0328176721627088 -10.8654988483412 619.050815125423 -0.0175518690596342 0.986004401085603 -2968.94615508951 1252.42933952463 -2.37054982775827 0.0181967133697159 SQSTM1 other 1 1 1 -0.0175518690596342 -2.37054982775827 0.245056720415316 65.0087411935737 97.4187569802136 0.667312365798071 0.504925652267441 -205.152178775114 191.636042533106 -1.07053024088448 0.284972963255425 MGAT4B other 1 1 1 0.667312365798071 -1.07053024088448 0.00932399639790191 175.739814366124 68.2934875197436 2.57330267860926 0.0104028222387915 -44.3903716405117 134.342646988669 -0.330426507408745 0.741236433399363 MAML1 other 1 1 1 2.57330267860926 -0.330426507408745 0.0002031100751103 -416.694666043131 117.340880614207 -3.5511465728056 0.000425132710050656 -1049.15004676496 326.249736823004 -3.21578817804269 0.00139721859552012 CELF5 other 0.965991517224589 1 1 -3.5511465728056 -3.21578817804269 7.03290593106355e-09 409.566553945921 66.2921786511371 6.17820325533827 1.48323291680581e-09 195.504661907346 183.306441107312 1.06654551103795 0.286764644851933 MFSD12 other 4.83863928057173e-05 1 1.39557385142259e-05 6.17820325533827 1.06654551103795 0.404533806890684 -0.198588403229967 7.64743752187885 -0.0259679667420385 0.97929474248518 -14.2906594060188 12.8086449084981 -1.11570423788838 0.265161892138249 USP41 other 1 1 1 -0.0259679667420385 -1.11570423788838 5.75563248985448e-09 44.3772500183992 9.2394238436191 4.80303217706014 2.15251419893891e-06 -9.70724644130396 15.6260241199264 -0.621223055001253 0.534777513421606 TUBA3FP other 3.97368867099553e-05 1 0.0191229361433733 4.80303217706014 -0.621223055001253 0.103015850921549 -23.6927760346632 13.3345117625192 -1.77680116502347 0.0762981204988502 -0.610301807858854 21.8886456196647 -0.0278821183577736 0.977768927809097 YDJC other 1 1 1 -1.77680116502347 -0.0278821183577736 2.45264740560332e-10 188.649573102829 77.7794835160991 2.42544131915946 0.0156967347451615 -534.783867598469 135.357877312782 -3.95088840202998 9.08584145212008e-05 PCYT1A essential 1.78258413439249e-06 0.725867873609873 1 2.42544131915946 -3.95088840202998 0.0877291794068123 29.2050647747765 18.486703482219 1.57978759181521 0.114877379875282 57.2078054245517 26.1488003058624 2.18777935336965 0.0292134806782065 FBXO27 other 1 1 1 1.57978759181521 2.18777935336965 1.73969794236024e-08 -11.6733560053176 13.3056344839297 -0.877324265852676 0.380792588523256 -70.8446101822252 17.714232288065 -3.99930457217481 7.45869901865855e-05 DMKN other 0.000117464405068164 0.599047554097673 1 -0.877324265852676 -3.99930457217481 7.56695663737047e-38 185.295025843809 21.7276880221242 8.52805994154245 2.48507128821803e-16 25.9144723735024 28.7057407321826 0.902762712701895 0.36715145789786 U2AF1L4 other 7.02894602045343e-34 1 2.41598630640557e-12 8.52805994154245 0.902762712701895 0.164734915125114 -78.3006817215564 53.5404803353178 -1.46245758781334 0.144341275475025 -174.73808593943 96.5065633354928 -1.81063421906316 0.0708904631307716 BDH1 other 1 1 1 -1.46245758781334 -1.81063421906316 1.75707651158674e-41 38.7402418475365 13.1804929284726 2.93921039658914 0.00346530362313831 -96.5827686140461 17.329866045031 -5.57319764406024 4.38814971250273e-08 THAP8 other 1.64690781431025e-37 0.000401208528214124 1 2.93921039658914 -5.57319764406024 0.0336594917884438 116.972917172943 46.1990038383879 2.53193591753913 0.0116936096108326 108.622045842982 60.7429898318614 1.78822356528138 0.0744342067407706 COX7A1 other 1 1 1 2.53193591753913 1.78822356528138 4.04439883098682e-12 37.0997566109723 15.2766175049229 2.42853214064022 0.0155635306412919 -33.6561768188396 20.0709087944628 -1.67686362204609 0.0942859171366283 ZNF382 other 3.0770635852671e-08 1 1 2.42853214064022 -1.67686362204609 0.000216088503948301 15.9489824505953 7.57589284186177 2.10522809436621 0.0358403285931091 -3.96611121886423 8.79272897509674 -0.451067152200104 0.652164380342748 LRRC56 other 1 1 1 2.10522809436621 -0.451067152200104 0.995206753319881 6.10488912877492 63.5105479807274 0.0961240191255708 0.923466140067866 5.63458822471196 149.011550904394 0.0378130969747918 0.969853969335531 PLXDC1 other 1 1 1 0.0961240191255708 0.0378130969747918 0.0292767276322663 88.3867674178046 33.2725274570492 2.65644885354445 0.00818585368194288 21.7603877119609 78.0656296712864 0.278744792088248 0.780572540786728 PGAP3 other 1 1 1 2.65644885354445 0.278744792088248 0.118307711793586 -3.79166104439335 15.021055577248 -0.252423075388688 0.800832748578873 69.2731615166647 35.2431345493358 1.96557889649944 0.0499800925630511 IKZF3 other 1 1 1 -0.252423075388688 1.96557889649944 4.85766498968863e-35 89.3578368766117 14.2580505021997 6.26718476434248 8.87469826540687e-10 -2.829397093413 17.8571944264936 -0.158445779658153 0.874179241171812 ZNF577 other 4.47342368900426e-31 1 8.3715028737583e-06 6.26718476434248 -0.158445779658153 1.03139790680916e-21 30.5203595046653 7.47467967679938 4.08316621237928 5.28188118373666e-05 -7.19402026969327 9.12055634226396 -0.788769895138603 0.430673227924065 TMEM143 other 8.9504710352899e-18 1 0.444840033294302 4.08316621237928 -0.788769895138603 1.69485168854752e-23 207.928666203771 44.9036469416545 4.63055186751185 4.8139864278504e-06 -23.8615667934622 54.7911428466529 -0.435500439555438 0.663413749943658 ALDH16A1 other 1.48791029737587e-19 1 0.0422956847550936 4.63055186751185 -0.435500439555438 0.615264480720378 -15.095396171337 158.379886647775 -0.0953113207165507 0.924111340181086 176.003856548272 242.022945244355 0.727219712042478 0.467481665920973 ITGA5 other 1 1 1 -0.0953113207165507 0.727219712042478 2.19453306676287e-15 -15.7202221552861 9.43674550939445 -1.66585208212263 0.0964578619441522 -61.5347223736806 11.5252233525349 -5.33913491230922 1.5028105203866e-07 SIGLEC11 other 1.77515779770449e-11 0.00135733846201317 1 -1.66585208212263 -5.33913491230922 0.00478563539124482 -23.1566084921208 526.3665276698 -0.0439933150662791 0.96492987322001 -2135.40356404393 804.349466343546 -2.65482063878424 0.00822549471903147 ZNF385A other 1 1 1 -0.0439933150662791 -2.65482063878424 1.64273503687919e-17 -0.0528031425235692 4.82869252232456 -0.0109352878195171 0.991280055520303 -25.0395232220297 5.89734668219074 -4.24589642960045 2.66014869096556e-05 SIGLEC16 other 1.36724837119455e-13 0.220446522020316 1 -0.0109352878195171 -4.24589642960045 0.365166802051409 -6.23564897473354 12.8565869760855 -0.485015890012834 0.627908668120675 36.6137531785968 30.1647837476876 1.21379133644223 0.225484503770712 MPP3 other 1 1 1 -0.485015890012834 1.21379133644223 0.352380494580971 18.3348625916435 17.4378016498929 1.05144346516616 0.293636029676819 -31.3334008006116 40.9134222712461 -0.765846489029414 0.444181098464843 CD300LG other 1 1 1 1.05144346516616 -0.765846489029414 0.677140854001705 2.11361489677501 6.15802910435904 0.34322911778362 0.731591156871075 -10.552071245446 14.4482687762888 -0.73033464485123 0.465576996215179 NAGS other 1 1 1 0.34322911778362 -0.73033464485123 0.000166075094172866 76.8048396527692 20.2648898323855 3.79004476649197 0.00017175805012026 -50.3158997886029 47.5464747012858 -1.05824669662086 0.290527589546695 LSM12 essential 0.800703694915725 1 1 3.79004476649197 -1.05824669662086 0.00435500639716972 13.3050656004813 4.72661156509783 2.81492680691774 0.00509883791104683 -11.4024322358609 10.6938644651939 -1.06625928100859 0.286893832631347 ASB16 other 1 1 1 2.81492680691774 -1.06625928100859 2.35336626120366e-34 1206.532247522 319.958947271423 3.770897041046 0.000184982131513864 -1047.3879386137 391.327232177297 -2.67650153756529 0.00771866641192812 EMC10 other 2.16274359404616e-30 1 1 3.770897041046 -2.67650153756529 1.24717241185831e-16 252.915294284476 52.8471371283184 4.78578988432942 2.33246287478296e-06 50.7421510846422 64.6664813505904 0.784674688105307 0.4330685107157 JOSD2 other 1.02754535013006e-12 1 0.0206959430879492 4.78578988432942 0.784674688105307 8.04605203909593e-05 -322.431654467058 153.731487836999 -2.09736898408822 0.0365348879187085 -16.4983964639192 188.137066281256 -0.0876934927817725 0.930160461341058 SHANK1 other 0.403348588719879 1 1 -2.09736898408822 -0.0876934927817725 0.025776286026951 98.1834781866734 59.4313994553324 1.65204721891946 0.0992415841695186 -231.4403866548 134.462356806544 -1.7212280979708 0.085915574966118 FAM171A2 other 1 1 1 1.65204721891946 -1.7212280979708 0.00160830496691241 68.36391709432 21.2799196178639 3.21260222416115 0.00141244368642881 -42.1474619175896 48.1453940289988 -0.875420437772376 0.381824987935957 DBF4B other 1 1 1 3.21260222416115 -0.875420437772376 0.0409043449233007 794.98360047462 366.060081915178 2.17172983275142 0.0304120034366723 -717.627712017486 819.849366123975 -0.875316541879193 0.381881437808046 PLCD3 other 1 1 1 2.17172983275142 -0.875316541879193 0.226333925602999 15.1696464067059 189.200986559348 0.0801774170556321 0.936132771059664 -377.044236077193 286.204828963842 -1.3173929924321 0.188395643463994 FMNL3 other 1 1 1 0.0801774170556321 -1.3173929924321 0.290978375605167 28.7907670454552 20.2291281619837 1.42323321177832 0.155382073165356 43.0186049952662 30.9104503027928 1.39171718864864 0.164716010559443 AQP5 other 1 1 1 1.42323321177832 1.39171718864864 0.00136849562976777 116.005397727274 100.386532443679 1.15558725760707 0.248481442647468 -319.137671638254 153.39232107894 -2.08053225476663 0.0380587299963174 RACGAP1 essential 1 1 1 1.15558725760707 -2.08053225476663 2.58096512476559e-05 69.4793698025983 61.586072527906 1.12816692071272 0.25986701020667 -275.707041455229 94.0984477923941 -2.92998500956691 0.00356695719006538 LARP4 other 0.137617060452501 1 1 1.12816692071272 -2.92998500956691 0.13692272723362 115.354234467453 69.433763677586 1.66135649801583 0.0973590581615665 9.16786242603629 107.233086225692 0.0854947176167331 0.931907249930613 GRASP other 1 1 1 1.66135649801583 0.0854947176167331 0.64968571157627 -9.84131292141954 36.4892253424621 -0.269704627299043 0.787514517512596 -79.2260718374964 85.668460421588 -0.924798595044342 0.355579902188161 IP6K3 other 1 1 1 -0.269704627299043 -0.924798595044342 3.62227043069803e-11 317.952716169797 55.1225873659911 5.7681021766762 1.51689505046329e-08 -216.126295181149 129.415386316894 -1.67002009059363 0.0956298226876493 LEMD2 other 2.69641810861161e-07 1 0.000140752691732489 5.7681021766762 -1.67002009059363 0.0123252169770908 4.19004146987684 5.96550479289509 0.702378359475492 0.482817185686183 40.9370464232232 13.9049017024612 2.94407305417895 0.00341197561665564 TREML1 other 1 1 1 0.702378359475492 2.94407305417895 0.0153929225179372 25.9051376569527 15.3960830800866 1.6825797524085 0.0931707691409807 -55.2436931229116 35.8864889500216 -1.53940089262698 0.124430204374256 ADCY10P1 other 1 1 1 1.6825797524085 -1.53940089262698 0.000592008356348206 67.2903231379489 17.4033639340062 3.86651243938324 0.00012713989598343 -8.19057433693142 12.68293761271 -0.645794735182122 0.518750477165837 MED11 essential 1 1 1 3.86651243938324 -0.645794735182122 0.0224812205179232 -232.473546362972 146.826223793352 -1.583324425003 0.114069287570938 252.669834008265 107.001602870705 2.36136494435115 0.0186447253368181 CXCL16 other 1 1 1 -1.583324425003 2.36136494435115 0.280610790554323 -6.99171596201944 17.4756180600614 -0.400084044981405 0.68928966288716 19.9577686827084 12.7355937874871 1.56708583955601 0.117816773233525 SCIMP other 1 1 1 -0.400084044981405 1.56708583955601 0.0013033248856321 712.646334556664 202.113579114007 3.52596959432735 0.00046642362172108 136.248402881609 151.080179541583 0.901828441659403 0.367643645627943 RNASEK-C17orf49 other 1 1 1 3.52596959432735 0.901828441659403 0.00665841436003586 2.54347899959243 28.6456852478365 0.0887909986298731 0.929288594890626 -68.1809161342937 21.4126892874111 -3.18413606152584 0.00155545123402432 BCL6B other 1 1 1 0.0887909986298731 -3.18413606152584 0.0813635973244412 -39.0582875583328 66.2672692691877 -0.589405418226488 0.555893229613028 108.989141707381 49.941412750387 2.1823399800907 0.0296150239671265 TNFSF13 other 1 1 1 -0.589405418226488 2.1823399800907 0.000970106108602879 775.106321951553 206.45657261507 3.75433105438937 0.000197242130916832 -24.2013510890115 155.593146084166 -0.155542526763487 0.876465287125591 SENP3 other 1 1 1 3.75433105438937 -0.155542526763487 1.92374375317349e-05 -35.3341545466889 101.600145502033 -0.347776613626816 0.728175021587114 -356.214897376647 75.9462490901701 -4.69035537164867 3.65000556402902e-06 FGF11 other 0.103862925233837 0.0315214480509546 1 -0.347776613626816 -4.69035537164867 0.00432445399271219 1348.78862170495 407.594650435093 3.30914211034214 0.00101310499443303 56.4972183112632 307.178081981017 0.183923338367464 0.854158713101612 EIF4A1 essential 1 1 1 3.30914211034214 0.183923338367464 0.000120064494507717 1068.18197449492 320.44258756054 3.33345821049179 0.00093057808708163 639.882794952578 249.796158887482 2.5616198335572 0.0107522789375964 RPL26 essential 0.589516668032891 1 1 3.33345821049179 2.5616198335572 0.505665996528008 61.0867465965145 53.6649886534105 1.13829795047636 0.25561832386804 14.9752223490716 129.995051816722 0.115198402860633 0.908340656903867 CYB561A3 other 1 1 1 1.13829795047636 0.115198402860633 0.300969806399451 30.9730970033078 19.9747307650904 1.55061399162582 0.12171644312503 21.3442428399315 48.3856649556559 0.441127405389446 0.659338429329761 PPP1R32 other 1 1 1 1.55061399162582 0.441127405389446 0.0245089353514753 63.4746460397152 102.10001970285 0.621690830466541 0.534469366419362 -574.286031573705 247.319767696787 -2.32203853708038 0.0206896252110024 ASRGL1 other 1 1 1 0.621690830466541 -2.32203853708038 0.000125069584262627 2616.41829605833 867.687979750884 3.01539073620624 0.00271643484743667 -821.391852003492 1325.92846766873 -0.619484287450043 0.535920947554902 RPL29 essential 0.611840406212773 1 1 3.01539073620624 -0.619484287450043 4.33666678094612e-27 0.70823811249964 28.6440015291654 0.0247255297685454 0.980285152049544 -232.128920690459 36.7816888201786 -6.31099136924653 6.79942580479024e-10 TAL1 og 3.88001576891249e-23 6.38330094553708e-06 1 0.0247255297685454 -6.31099136924653 3.00570906081613e-85 158.060229475642 89.0507759780842 1.77494499895814 0.0766014026334907 -1357.75416826462 114.34987279575 -11.8736832413432 2.20538107276354e-28 CMPK1 essential 2.9555137195005e-81 2.17141820424298e-24 1 1.77494499895814 -11.8736832413432 2.32611761890825e-23 84.1130695800608 18.5553020581685 4.53310160709738 7.51861043206362e-06 -34.4403824710178 23.8456293534771 -1.44430587092036 0.149371168737557 BEND5 other 2.0409355988301e-19 1 0.0656073946301871 4.53310160709738 -1.44430587092036 0.0125677018043054 -14.2300991585017 125.996724070042 -0.112940231291975 0.910129922176723 241.936913068522 161.919820680253 1.49417725422437 0.135852641847354 ELAVL4 other 1 1 1 -0.112940231291975 1.49417725422437 3.4748406426493e-09 61.0918106655063 33.9758774426489 1.79809368481002 0.0728522321353749 -76.6631058830132 43.6444114101498 -1.75653888793617 0.0796968130624869 COA7 other 2.41848908728391e-05 1 1 1.79809368481002 -1.75653888793617 2.42232874085385e-15 -8.85729024832069 95.1686178600831 -0.0930694429264769 0.925891045617881 -567.358988756159 122.250803330452 -4.64094282654775 4.59176340342566e-06 ZYG11B other 1.95821055410625e-11 0.0395121240864778 1 -0.0930694429264769 -4.64094282654775 0.536008010950451 -0.816237785044843 76.0334010344291 -0.0107352528486163 0.991439559877569 -59.2282953506705 97.6294364765968 -0.606664316503234 0.54438802187786 SLC1A7 other 1 1 1 -0.0107352528486163 -0.606664316503234 2.62147401897302e-76 217.061152990402 47.8841520550991 4.5330478597728 7.51186516772319e-06 -507.756483910605 61.4848568878581 -8.25823641155577 1.76470990600262e-15 C1orf123 other 2.56852024378977e-72 1.71653332556875e-11 0.0655560473187203 4.5330478597728 -8.25823641155577 7.01678549144896e-56 116.584031726113 20.1019005112235 5.79965221004952 1.27423962686664e-08 -116.743590371006 25.8115143123835 -4.52292682087996 7.86340749950314e-06 MAGOH essential 6.7578661068145e-52 0.0669254612282713 0.000118338634147105 5.79965221004952 -4.52292682087996 0.0102759496755233 31.9894718592884 34.6388583429407 0.923514035669937 0.356247855475495 -34.3139529385806 44.4796690629633 -0.771452523399115 0.440854738373727 ACOT11 other 1 1 1 0.923514035669937 -0.771452523399115 0.0258046041572672 12.6808617945121 11.5616071412209 1.09680787797232 0.273328031141946 -5.99253118427573 14.846230045636 -0.403639925142962 0.686674506022718 FAM151A other 1 1 1 1.09680787797232 -0.403639925142962 2.14621056201877e-49 15.8842928966572 8.58047651289951 1.85121337641067 0.0648118059259653 -83.0818312520467 11.0181678598562 -7.54043978171261 2.72292851853091e-13 PARS2 essential 2.0468410129973e-45 2.62463079901194e-09 1 1.85121337641067 -7.54043978171261 1.40027616169117e-20 169.84292279266 125.986306708928 1.34810621272561 0.178322577247207 -681.809783955885 161.845826900036 -4.21271154786711 3.06638308631171e-05 USP24 other 1.20284261219458e-16 0.253221915267621 1 1.34810621272561 -4.21271154786711 1.65728008266987e-44 -127.742984587405 447.026678912913 -0.285761433519029 0.77519625142512 -5059.41775107729 574.264016344172 -8.81026428102895 2.96498515353704e-17 PLPP3 other 1.56463812604862e-40 2.89767999055175e-13 1 -0.285761433519029 -8.81026428102895 2.3424227910458e-70 158.802878003975 28.8702688462489 5.50056803591589 6.44824522782751e-08 -233.73237832312 36.909626900494 -6.33255868321962 5.98299042853894e-10 NOL9 essential 2.28737585545622e-66 5.62101950761234e-06 0.0005921423592714 5.50056803591589 -6.33255868321962 5.49054004416914e-11 43.6642068918223 21.2122856896574 2.05843950673886 0.0401402843408604 -51.2231228211443 27.2499449151575 -1.87975142631029 0.0608070315745599 PRKAA2 other 4.06958828073817e-07 1 1 2.05843950673886 -1.87975142631029 2.0263600922348e-34 -47.3372979835986 85.4086723621687 -0.554244629665575 0.579694303259227 -831.31523553517 109.191994288054 -7.61333503390478 1.65731053418556e-13 KLHL21 other 1.86283283279145e-30 1.59880747232881e-09 1 -0.554244629665575 -7.61333503390478 0.0208320694644016 -27.1966403878625 35.6000607047571 -0.76394927001426 0.445308802811662 -95.9893037325568 45.9339350578756 -2.08972524586915 0.0372187898378314 ZSWIM5 other 1 1 1 -0.76394927001426 -2.08972524586915 5.05541838778671e-40 101.38122021089 18.1043937748052 5.59981303278856 3.79419956096219e-08 -62.5704154701502 23.2466486825215 -2.69158863820208 0.00738358063590347 GMEB1 other 4.72226631603157e-36 1 0.000349673431538275 5.59981303278856 -2.69158863820208 0.0179722054681338 58.7551020408165 23.5465495863861 2.49527438511785 0.012955615596133 42.2693877551021 30.1404053967694 1.40241603252068 0.161504284030866 SLC45A1 other 1 1 1 2.49527438511785 1.40241603252068 9.31664726191517e-28 367.659368845578 467.981789266924 0.785627512176281 0.43251051544306 -3439.48231005377 600.860136949766 -5.72426443117714 1.93015046902534e-08 SELENON other 8.36448591174744e-24 0.000177573843150332 1 0.785627512176281 -5.72426443117714 7.19430701180923e-06 -115.635111044047 217.853834832116 -0.530792176016355 0.595831827787014 -860.728055707142 279.761919582795 -3.07664480209006 0.00222469643276432 AK4 other 0.0405327257045332 1 1 -0.530792176016355 -3.07664480209006 8.72151340031466e-13 -83.516071864115 385.132188934199 -0.216850406857018 0.828425895340274 -2129.31905269088 494.576193953098 -4.30534077200815 2.05910750867073e-05 JAK1 og 6.72341468030257e-09 0.171400109021752 1 -0.216850406857018 -4.30534077200815 8.49993147742244e-16 -3.31494063087403 55.9073887989148 -0.0592934261837387 0.952745439662616 -337.259836219468 71.7947353155349 -4.69755664864875 3.5296522033074e-06 RAVER2 other 6.91894422262186e-12 0.0304856060799661 1 -0.0592934261837387 -4.69755664864875 3.16477568394658e-58 89.3756810302146 36.6738873609186 2.43703865234252 0.0152052558782653 -368.795195641406 46.8708433985567 -7.86832855780791 2.83924496043332e-14 LZIC other 3.0565403555556e-54 2.75037659317176e-10 1 2.43703865234252 -7.86832855780791 0.687225166935764 10.9904590599827 16.78056738384 0.654951576343404 0.51284273372833 18.3446547274576 21.4463042394858 0.855376036943576 0.392810662407515 RBP7 other 1 1 1 0.654951576343404 0.855376036943576 9.98273798096407e-05 -49.6524735123072 49.2315450245639 -1.00854997517411 0.313747336464079 -194.86162670278 62.9066747168918 -3.09763037991985 0.00207620748004884 FBLIM1 other 0.495343458615437 1 1 -1.00854997517411 -3.09763037991985 4.79102127023693e-08 10.0684272019969 9.72006493275641 1.03583950021429 0.300848564605378 -27.5955893677474 12.420023841358 -2.22186283377779 0.0268028521007342 SLC25A34 other 0.000314722187241864 1 1 1.03583950021429 -2.22186283377779 4.14026125554308e-08 7.92951435398328 4.43279742296224 1.78882849753246 0.0743333737944551 -8.52044833501597 5.66430786043069 -1.50423468232324 0.133241663549744 AKR7A3 other 0.000272843216740289 1 1 1.78882849753246 -1.50423468232324 5.95082007048014e-07 62.9130715813737 121.352656494162 0.518431762426232 0.604418853737803 -376.262766496625 155.052495907237 -2.42667984346239 0.0156402624700714 DRAXIN other 0.00366808549144396 1 1 0.518431762426232 -2.42667984346239 2.49983294068986e-13 1383.86707726706 342.096864454087 4.04524922926556 6.17735382699377e-05 -81.5023394470631 439.231554603777 -0.185556658197257 0.852878342349731 PDPN other 1.95236952667878e-09 1 0.518712400852667 4.04524922926556 -0.185556658197257 1.63715189944589e-36 -99.6734176859133 150.200433674162 -0.663602729018348 0.507293735932083 -1544.03654604495 191.910259893726 -8.04561750320172 8.12383153077798e-15 DHRS3 other 1.51551151331706e-32 7.88011658485464e-11 1 -0.663602729018348 -8.04561750320172 0.0068101918897096 0.394009361849666 2.18871997517487 0.180018168755547 0.857221559324741 -4.34497698063713 2.81052970058743 -1.54596373051279 0.122835517974787 MATN1 other 1 1 1 0.180018168755547 -1.54596373051279 1.30181863931849e-27 441.57911866223 712.044461003287 0.620156665554333 0.535477158488639 -5368.16759917414 914.33446420144 -5.87112026217078 8.56120791885537e-09 LAPTM5 other 1.16773131946869e-23 7.91226835860613e-05 1 0.620156665554333 -5.87112026217078 0.00354680463304469 4560.41157465051 2199.26360762703 2.07360843822225 0.0386996056044125 909.306238080999 2824.06875194849 0.321984455036237 0.747618086290284 SDC3 other 1 1 1 2.07360843822225 0.321984455036237 2.78642695328642e-68 322.435583199573 64.3856518149418 5.00787945932928 7.99988767594728e-07 -566.906114247242 82.7117591641304 -6.85399657770901 2.45525739495141e-11 PEF1 other 2.71732356484492e-64 2.33642293703577e-07 0.00719749894204977 5.00787945932928 -6.85399657770901 2.79915832926856e-29 232.97892593854 64.7465480476524 3.59832196408481 0.00035700058279651 -275.419681890303 83.2101216943821 -3.30993004555236 0.00101068981058718 SYNC other 2.52596047633195e-25 1 1 3.59832196408481 -3.30993004555236 5.39927079138764e-81 949.023804397117 172.506951783914 5.50136556575347 6.43605652940561e-08 -1758.59262932914 221.700227794412 -7.93229960485169 1.82809884699215e-14 RBBP4 essential 5.3053234796175e-77 1.77179340250479e-10 0.000591151792225905 5.50136556575347 -7.93229960485169 0.0284523745592044 44.7364767197849 80.480259204117 0.555868944287599 0.578585579989993 -96.6205839423782 103.430566791627 -0.934158894604454 0.350738994775337 KIAA1522 other 1 1 1 0.555868944287599 -0.934158894604454 5.55783160892432e-32 19.4738006025445 9.92727620259311 1.9616458941132 0.0504395965074992 -67.0820918571753 12.758206975043 -5.25795607395288 2.28644776053453e-07 TSSK3 other 5.06596351153452e-28 0.00205688840537686 1 1.9616458941132 -5.25795607395288 7.91598826475027e-14 -35.8225958225673 35.7572655442901 -1.00182704905654 0.316981532446644 -233.004177965482 45.7101946258754 -5.09742257438527 5.13663229635348e-07 TMCO4 other 6.24254834558206e-10 0.00457519838636204 1 -1.00182704905654 -5.09742257438527 0.21409714471071 86.0074307478695 52.8155555491439 1.62844885097992 0.104152066821952 69.1882770433773 67.5447549366032 1.02433234243453 0.306246308616168 UBXN10 other 1 1 1 1.62844885097992 1.02433234243453 0.208711424591445 -792.461019631961 642.162568424606 -1.23405047039113 0.217848860302648 -300.74672625685 821.24883214265 -0.366206580132599 0.714388561477499 CAMK2N1 other 1 1 1 -1.23405047039113 -0.366206580132599 5.01768584966853e-13 -66.0691032419734 71.8181283201794 -0.919950224091392 0.358106298915273 308.86558262213 92.2519653824487 3.34806506659957 0.000884219485883374 ALPL other 3.89021183924801e-09 1 1 -0.919950224091392 3.34806506659957 0.30271722698727 -6.87378281509365 13.5203242445109 -0.508403695856949 0.611427989032534 -21.0420089586219 17.3815546850458 -1.21059418100991 0.226708322715285 WNT4 other 1 1 1 -0.508403695856949 -1.21059418100991 0.346992667828147 80.0645281627555 57.0632298897364 1.40308440860191 0.161305027565004 70.3423166047226 75.7933202895688 0.928080684893859 0.353880386800238 SCNN1D other 1 1 1 1.40308440860191 0.928080684893859 3.00828238158561e-09 214.6093278272 76.0900155024701 2.82046634384288 0.00501420599848459 -97.5258125244861 101.012208131286 -0.965485403484411 0.334836952287459 MXRA8 other 2.10278938472834e-05 1 1 2.82046634384288 -0.965485403484411 5.91478875119627e-18 504.371410105363 100.753171512121 5.00601025789731 8.06702196942839e-07 7.90553102984695 128.735986329036 0.0614088667456293 0.951061602020693 FAAP20 other 4.9453548748752e-14 1 0.00725628626150084 5.00601025789731 0.0614088667456293 0.227459021968212 -7.99905311758936 64.4577502350229 -0.124097615700572 0.901295176470312 -83.5626576391625 82.4336362716518 -1.01369612476866 0.311289975010273 MEGF6 other 1 1 1 -0.124097615700572 -1.01369612476866 4.10816868340648e-06 -0.554472099549595 2.79419008231819 -0.198437501821486 0.842794849910958 -10.1178733056417 3.57026995013198 -2.83392389005982 0.00481055137585382 CCDC27 other 0.023720565977989 1 1 -0.198437501821486 -2.83392389005982 2.44125437609853e-09 60.3212811168099 62.9200300191133 0.958697589598831 0.33824000187084 -210.50086066372 80.8001768337896 -2.60520296999761 0.00949450046884629 DIRAS3 other 1.71229581939551e-05 1 1 0.958697589598831 -2.60520296999761 0.00022556128647519 0.566297341171633 6.73119159829192 0.0841303256492259 0.932991251634092 -18.5273141508228 8.64350584904427 -2.14349529859709 0.0326234660191866 C1orf87 other 1 1 1 0.0841303256492259 -2.14349529859709 4.89912671600623e-83 949.68727639521 247.667246969818 3.83452914349609 0.000144255173616517 -3098.28128540683 318.028875948729 -9.74213827648252 1.9813016216977e-20 NFIA other 4.81584156183412e-79 1.94365689088544e-16 1 3.83452914349609 -9.74213827648252 3.53050426858655e-59 50.3561049031505 10.9717021184647 4.58963471295893 5.80783581600655e-06 -86.6336515241463 14.0887345204949 -6.14914358689349 1.75621508054418e-09 OMA1 other 3.41364457729633e-55 1.63907553467188e-05 0.0508824495840334 4.58963471295893 -6.14914358689349 5.02680090081598e-19 97.594847830541 41.8295565737592 2.33315520948565 0.0200918365311126 -163.087771280871 53.7132261990525 -3.03626839833627 0.00253819212312893 MYSM1 other 4.25669500281097e-15 1 1 2.33315520948565 -3.03626839833627 5.55986996778873e-80 75.914679506375 20.2818468327543 3.74298653038717 0.000206075540779444 -246.348678991526 26.0438674443343 -9.45898989533975 1.9167974674581e-19 TM2D1 other 5.4581243473782e-76 1.87884487760243e-15 1 3.74298653038717 -9.45898989533975 1.29273636338182e-45 341.833212501379 63.6203593855601 5.37301605653873 1.2604430178624e-07 -300.110722347432 81.6947401418387 -3.67356235941724 0.000268794925152406 USP1 other 1.22344569430455e-41 1 0.00115166678542088 5.37301605653873 -3.67356235941724 1.20624792291576e-17 162.954022631354 113.320233824716 1.43799582061763 0.151152591300276 -537.502727267882 145.662039750895 -3.69006728305533 0.000252569674323468 FUBP1 other 1.00540764375028e-13 1 1 1.43799582061763 -3.69006728305533 3.23804342397848e-22 -29.3271672653126 19.2765342194567 -1.52139212015152 0.128884688858376 -170.394947092515 24.7661775037864 -6.88014721151311 2.0810094671815e-11 NEXN other 2.82227864833964e-18 1.9813291137035e-07 1 -1.52139212015152 -6.88014721151311 6.68631960642291e-22 65.9037146595996 41.932735982164 1.57165310385737 0.116756399599814 -227.903006209149 53.9004169806572 -4.22822343454104 2.87149694624894e-05 DNAJB4 other 5.81442352974536e-18 0.2376163723021 1 1.57165310385737 -4.22822343454104 0.999042805667258 -1.78753099179007 51.7634237555789 -0.0345327040234161 0.972468095376714 -0.980217017102952 66.4731690640109 -0.0147460551513505 0.988241491008302 ADGRL4 other 1 1 1 -0.0345327040234161 -0.0147460551513505 1.62317076005265e-13 9.04748987141098 3.65635459051407 2.47445636013627 0.0137225501320895 -9.18618636603831 4.69732361824371 -1.95562135220161 0.0511466151948693 LRRIQ3 other 1.27289051003329e-09 1 1 2.47445636013627 -1.95562135220161 2.38247803267998e-39 28.7872011145638 17.2128231409022 1.67242763600806 0.0951541346980276 -143.141130426086 22.1042353789589 -6.4757331783728 2.53718244478204e-10 TYW3 other 2.22046952645774e-35 2.39256304542946e-06 1 1.67242763600806 -6.4757331783728 4.40621286540152e-69 40.5096251148639 31.8470597281219 1.27200518542981 0.204046203502318 -428.763891419829 41.0892575485064 -10.4349388867313 6.46578410834488e-23 SNX7 other 4.2995825140588e-65 6.35586577850302e-19 1 1.27200518542981 -10.4349388867313 0.000718416952363023 0.160596931595316 37.381378969162 0.00429617462019797 0.996574115138977 -99.208652501151 48.2296677022874 -2.05700468669092 0.0402774037759979 NTNG1 other 1 1 1 0.00429617462019797 -2.05700468669092 0.000180096103043935 79.772556500298 50.5338100375271 1.57859770401357 0.115150257972248 -49.2447986469474 65.1990090534396 -0.755299802280499 0.450475074236552 FAM102B other 0.863020525786539 1 1 1.57859770401357 -0.755299802280499 0.102728402447157 25.877670896677 14.6426814236966 1.76727678134133 0.077878170656674 15.9364593793658 18.8920708333937 0.843552806884276 0.399379792592001 HENMT1 other 1 1 1 1.76727678134133 0.843552806884276 0.00073838621006399 35.8788157665002 12.442356562831 2.88360292403779 0.00412571202458588 18.829963770225 15.5466216698338 1.21119328495413 0.226475910376327 AKNAD1 other 1 1 1 2.88360292403779 1.21119328495413 3.89663007615602e-31 69.5898745454731 23.8795733663555 2.91420091464112 0.00374869878003935 -131.57340281159 30.8112612873545 -4.27030239315748 2.39549605915112e-05 C1orf52 other 3.54164707621821e-27 0.198802217948952 1 2.91420091464112 -4.27030239315748 0.00721426800355904 67.6496363787046 24.6122017270808 2.74862188799101 0.00623197807267241 47.0277507277605 31.7565547187956 1.4808832741521 0.139356654934672 WDR63 other 1 1 1 2.74862188799101 1.4808832741521 8.66487603793421e-06 128.159561720659 522.469777955091 0.245295646041511 0.806342410993523 -1632.11137585596 674.130672116661 -2.42106084675155 0.015880792248564 GBP2 other 0.0484799814322419 1 1 0.245295646041511 -2.42106084675155 8.52504528491513e-20 129.212305544476 32.9900990209882 3.91669953649644 0.000104100084069014 -81.3880305514927 43.8762640952647 -1.85494440398986 0.0642759216160855 ATXN7L2 other 7.26163357369071e-16 1 0.864134797856886 3.91669953649644 -1.85494440398986 0.000360094366169045 -74.2957435934615 89.1647861824456 -0.833240865305731 0.40516303495285 -324.020470532171 115.047261630274 -2.816411846233 0.00507574982366571 GBP4 other 1 1 1 -0.833240865305731 -2.816411846233 7.26906414647248e-34 86.1297079979427 44.2811881732509 1.94506316454199 0.0524069389359184 -317.096186120232 57.1349930749944 -5.54994704740783 4.95751646473563e-08 ZNF326 other 6.67082016721779e-30 0.000452968279382894 1 1.94506316454199 -5.54994704740783 1.0551574884294e-09 28.9762515237217 14.407477945784 2.01119527184151 0.0449169972437251 -31.1482792735861 18.5896356132052 -1.67557234158263 0.0945356635390751 HFM1 other 7.50639037268672e-06 1 1 2.01119527184151 -1.67557234158263 2.94112425041517e-24 148.690868063231 40.1867912263611 3.69999354329378 0.000243052039443502 -129.27463617992 51.8492265485316 -2.49327993463735 0.0130250139826852 AGL other 2.59230691431593e-20 1 1 3.69999354329378 -2.49327993463735 1.09416759922957e-27 278.782652693301 263.322181161103 1.05871313789072 0.290313951877755 -1874.317241718 339.739775424508 -5.51692023513003 5.91184203178311e-08 VCAM1 other 9.82124837068458e-24 0.000538982638037667 1 1.05871313789072 -5.51692023513003 1.29962536181372e-44 181.820687890387 40.0488804381054 4.53996930504427 7.28019300024265e-06 -228.657914134109 51.6712932653421 -4.42524078040599 1.21737475283201e-05 EXTL2 other 1.2272362291607e-40 0.102661212906323 0.0635706452781188 4.53996930504427 -4.42524078040599 1.68236356101976e-46 69.0388610377697 27.8682709981302 2.47732846585287 0.0136132929432758 -239.010533884237 35.955801705066 -6.64734264152319 8.89673493083246e-11 SLC30A7 other 1.59555360127114e-42 8.4163112445675e-07 1 2.47732846585287 -6.64734264152319 0.510991360748606 -4.73112320551487 42.856054365116 -0.110395678641054 0.912146260465467 88.6612076178167 84.6868817034741 1.04692965231921 0.295710730176349 NLRP3 other 1 1 1 -0.110395678641054 1.04692965231921 0.000818842919914458 92.6313153905443 63.9685457019369 1.44807599381987 0.148312860888299 -354.792117100324 126.406799292582 -2.80674868033893 0.00522821570695183 ZNF496 other 1 1 1 1.44807599381987 -2.80674868033893 1.76678146565526e-45 67.4144324380919 10.3207554753313 6.53192807437652 1.80443390409408e-10 -32.8374705064594 13.3158973996767 -2.46603510982719 0.014043905981388 RBM15 other 1.67155194465644e-41 1 1.71294910515651e-06 6.53192807437652 -2.46603510982719 1.74075288833661e-08 -12.1281797773717 17.4513757409603 -0.694969838332319 0.487442707992515 -86.5098689467965 22.5158642121955 -3.84217403922427 0.000139976546718807 DENND2D other 0.000117518227491605 1 1 -0.694969838332319 -3.84217403922427 1.84050269171862e-05 -52.8476219888809 55.80265182396 -0.947044992693154 0.344138035865823 -318.079445785839 81.6982521942847 -3.89334456053504 0.000114281075486963 SNED1 other 0.0996080056758118 0.903734744950902 1 -0.947044992693154 -3.89334456053504 4.65171100445905e-07 242.749116687296 68.945250420024 3.52089687409117 0.000475185039659294 -529.540002250476 163.100153591786 -3.24671676015603 0.00125711089706336 BROX other 0.00288313048056372 1 1 3.52089687409117 -3.24671676015603 0.357150828849077 8.86560139794013 143.024055268187 0.0619867852391408 0.950601760867237 -389.842632666939 290.575981264863 -1.34162029142936 0.180417479884021 KIF26B other 1 1 1 0.0619867852391408 -1.34162029142936 9.90651150825658e-06 37.9692503155516 10.4558923701977 3.63137348503845 0.00031541946587195 -37.1580332824021 20.6620176275152 -1.79837390289124 0.0728093523852428 TFB2M essential 0.0551099235204314 1 1 3.63137348503845 -1.79837390289124 0.258676040226156 10.2721384441641 65.3256764200742 0.157245037588429 0.875124526637334 -191.913970637084 129.090873349857 -1.48665793062663 0.137827942944215 CNST other 1 1 1 0.157245037588429 -1.48665793062663 0.260186015882902 14.0994975224258 12.7678617882553 1.10429590766681 0.270071078774856 -23.1210123820684 27.7374347209869 -0.83356707693572 0.404979319899675 B3GALNT2 other 1 1 1 1.10429590766681 -0.83356707693572 0.0131388940756157 -13.517339934734 283.964376754082 -0.0476022383132946 0.962054945141705 -1936.59927984696 671.759594475784 -2.88287550452958 0.00413462070551172 CAPN2 other 1 1 1 -0.0476022383132946 -2.88287550452958 0.0108549718636048 174.428868999931 151.612262465477 1.15049314721261 0.250568539059782 -866.724293268023 355.71973212257 -2.43653701214802 0.0152260727879999 WDR26 essential 1 1 1 1.15049314721261 -2.43653701214802 0.00800781473522756 -62.6510897404921 38.1241809615026 -1.64334257577249 0.101029678940047 -219.061051941529 70.2355520495282 -3.11894824699396 0.00193475495390381 SLC16A14 other 1 1 1 -1.64334257577249 -3.11894824699396 0.0343149315965019 449.262501061208 206.782152324318 2.17263673876739 0.0303715506048223 -30.0518719755491 356.45891459334 -0.0843066921466482 0.932853147281375 SGCB other 1 1 1 2.17263673876739 -0.0843066921466482 0.227366707287477 25.8595806095592 36.0961280486418 0.716408712167459 0.474140997691586 106.449804737244 62.2238741623152 1.7107550143786 0.0878718537093511 SPATA18 other 1 1 1 0.716408712167459 1.7107550143786 4.55700324610582e-05 122.091866166718 88.2620273167636 1.38328871292002 0.167282628983309 -286.639989544271 128.326249370171 -2.23368165867161 0.0260093246508905 SMARCAD1 other 0.235733777921054 1 1 1.38328871292002 -2.23368165867161 0.0291455256580921 13.1069158357534 26.43599808466 0.495798032432108 0.620285588846073 -61.3268748370389 38.4326965643956 -1.59569534066607 0.111278068012466 HPGDS other 1 1 1 0.495798032432108 -1.59569534066607 1.14376300254967e-06 -702.925253769475 501.905644105044 -1.40051274980753 0.16206783281766 -3444.96213463043 729.671233220425 -4.72125250083656 3.15999285921943e-06 PDLIM5 other 0.0068946033793694 0.0273402582179665 1 -1.40051274980753 -4.72125250083656 0.0262670454102169 80.4461909918677 57.3294875112794 1.40322536419047 0.161258146136455 -100.800665222772 91.8838763746557 -1.0970441082803 0.273224871785737 MSX1 other 1 1 1 1.40322536419047 -1.0970441082803 1.47315786866091e-07 25.8834247302319 17.0100594256364 1.52165398618315 0.128820695017859 -103.520918872451 27.6929297806229 -3.73817142832197 0.00021005390271881 PACRGL other 0.000940169351779391 1 1 1.52165398618315 -3.73817142832197 0.570586120227084 -1.38793827559902 3.65215045121282 -0.380033159679417 0.704105855549013 3.52901753250804 5.87081550073544 0.601111980450749 0.548077782555229 C1QTNF7 other 1 1 1 -0.380033159679417 0.601111980450749 0.0265467233778658 149.945869449849 109.56278070767 1.36858400709934 0.171834093539199 -211.070730957946 178.371769127067 -1.18331915409543 0.237327482576778 DCAF16 other 1 1 1 1.36858400709934 -1.18331915409543 0.560758459538284 -5.94234014080411 10.1091833388476 -0.587816042268108 0.556958705025355 -17.5841664610181 16.4705336456417 -1.06761364503032 0.286282898592664 NPPC other 1 1 1 -0.587816042268108 -1.06761364503032 6.5453355522361e-05 11.4677865037821 45.1937731143102 0.253747047735453 0.799810324751113 -240.885590195144 69.8957831316955 -3.44635369119871 0.000623176312931751 GNPDA2 other 0.331709367026213 1 1 0.253747047735453 -3.44635369119871 0.00912961246694509 -411.859954285224 224.199567576922 -1.83702385663129 0.0668852746024508 -1092.23606088697 354.478555496218 -3.08124721214235 0.00219162119801288 GABRG1 other 1 1 1 -1.83702385663129 -3.08124721214235 0.339048282946198 -16.5690703735885 26.8291093934977 -0.61757809886914 0.537175160165903 -60.8743780112158 42.3152410232291 -1.43859225515929 0.150981875961788 GABRB1 other 1 1 1 -0.61757809886914 -1.43859225515929 1.17008702450254e-09 -21.337565428043 180.61424146661 -0.118138886805267 0.906012018261127 -1215.70204827615 253.185721630802 -4.80162167299822 2.16696540717067e-06 PAQR3 other 8.31229822206607e-06 0.0188829365580852 1 -0.118138886805267 -4.80162167299822 0.0107495133612043 85.313254315007 77.5312925942991 1.10037188160178 0.271777276645036 -137.083823593025 108.683656975551 -1.2613103700022 0.20787148212625 ANTXR2 other 1 1 1 1.10037188160178 -1.2613103700022 6.28564267814628e-20 21.2747547059004 11.5988893888571 1.83420618928728 0.0673015970727798 -96.3299648639622 16.5568130441467 -5.81814656039844 1.15005669978887e-08 HELQ other 5.36291033299441e-16 0.000106138732823515 1 1.83420618928728 -5.81814656039844 6.42743187257521e-12 24.5217296651444 22.2426342044101 1.10246517745108 0.270864885774988 -144.901770977836 31.7502067469967 -4.56380558818069 6.53368245605396e-06 MRPS18C other 4.86363769797766e-08 0.055810715539613 1 1.10246517745108 -4.56380558818069 0.0116994331629596 286.391465597067 129.709629688849 2.20794297450444 0.0277753646412996 -176.95505860565 220.687006494077 -0.801837232815968 0.423090005989225 CGGBP1 other 1 1 1 2.20794297450444 -0.801837232815968 8.37807207077315e-06 2.3017095333436 19.4175441120985 0.118537623504585 0.905696656535213 167.18718876739 38.2381497441223 4.37226146887741 1.54175477408937e-05 CLDN1 other 0.0469674720287543 0.12921446761643 1 0.118537623504585 4.37226146887741 7.16353206926399e-29 327.640317420288 228.734838773619 1.43240233615902 0.152741987243794 -1562.53358165175 293.717819192915 -5.31984605477911 1.66039769647127e-07 HIPK1 other 6.45434239440685e-25 0.00149767872221708 1 1.43240233615902 -5.31984605477911 0.910052228909863 0.49130276122116 87.0263153326953 0.00564545056679632 0.995498176400529 41.4746989417343 131.610078071763 0.315133153550136 0.752810636437057 COL6A3 other 1 1 1 0.00564545056679632 0.315133153550136 0.119059237130468 7.67323116585502 9.69253420358145 0.791664079247687 0.428985084151223 -18.4592125783763 16.1595693397265 -1.14230844834438 0.253949884365957 KBTBD8 other 1 1 1 0.791664079247687 -1.14230844834438 0.100948857581301 -1.22529361214557 4.87781689386139 -0.251197131587201 0.801779506814259 -15.5242687545754 8.13238505712124 -1.90894413453545 0.0569225365222817 FAM19A4 other 1 1 1 -0.251197131587201 -1.90894413453545 0.797444019746092 -14.8796906330564 22.4779048929836 -0.661969641027402 0.508338798330906 -17.6302555778351 37.4755719299632 -0.470446604811893 0.638270147063643 EOGT other 1 1 1 -0.661969641027402 -0.470446604811893 0.000211591352581611 32.77667562387 33.236802680113 0.98615609748412 0.324600955693586 -208.431232695453 66.0150475462659 -3.15732913089817 0.00170224338881016 POGLUT1 other 1 1 1 0.98615609748412 -3.15732913089817 0.813687718624558 15.7880472885101 26.92742023054 0.586318598415304 0.557963464145106 21.8790626856404 34.4138389998423 0.635763498682629 0.525262616411015 SLC22A15 other 1 1 1 0.586318598415304 0.635763498682629 0.00831932935713883 -782.678529824695 960.116471304697 -0.815191232748166 0.41540589711288 -2813.79669758224 1227.05009918115 -2.29313921205008 0.0223129658786769 ATP1A1 other 1 1 1 -0.815191232748166 -2.29313921205008 0.0136940763249902 -888.643000472161 414.037502293531 -2.14628625559179 0.0323988768415177 -2232.7127428167 801.646042515028 -2.78516031316258 0.00558216873965076 SLC15A2 other 1 1 1 -2.14628625559179 -2.78516031316258 0.00831853766374983 -52.8368535239175 67.3748525832633 -0.784222176347185 0.433334627687211 -329.789570238972 112.333987850424 -2.93579509238198 0.00350251573447508 EIF4E3 other 1 1 1 -0.784222176347185 -2.93579509238198 0.000410084519617873 86.0533666568688 151.603889523064 0.56761978157412 0.570583996568622 -1025.95932568852 309.734136212453 -3.31238699819898 0.00100171207046035 LRRC58 other 1 1 1 0.56761978157412 -3.31238699819898 0.312159962540263 -558.697254291123 1147.95451722242 -0.486689364351248 0.626727029849968 -3046.59027141489 2053.99926168021 -1.48324798759797 0.138742796166395 IGFBP7 other 1 1 1 -0.486689364351248 -1.48324798759797 0.328606404662544 -4.79443021766964 6.03118968202445 -0.794939385169582 0.42707930084069 -16.8869764038778 11.3223528942661 -1.49147236105225 0.136557366236219 NEK10 other 1 1 1 -0.794939385169582 -1.49147236105225 4.96994132468919e-06 92.8632522407187 45.9283589848125 2.02191531100483 0.043792563633432 -261.611377355037 86.2213121617544 -3.03418459770416 0.00255542216845399 AZI2 other 0.0284926736144431 1 1 2.02191531100483 -3.03418459770416 0.547470007968509 -102.721551188076 186.730095897104 -0.550107098133128 0.582527616174954 194.915958469163 347.042675632339 0.5616483855019 0.574644189292409 TGFBR2 ts 1 1 1 -0.550107098133128 0.5616483855019 0.00962417285930024 -138.967452963373 160.794759576112 -0.864253619519189 0.387921632367001 -1047.8742267512 345.151522594257 -3.03598320782443 0.00254054392575836 HDAC11 other 1 1 1 -0.864253619519189 -3.03598320782443 0.92945231205915 20.7462973895639 59.9691391511784 0.345949561444658 0.729546728000309 -1.00752586051963 128.725834979084 -0.00782691260603077 0.993758654605156 FBLN2 other 1 1 1 0.345949561444658 -0.00782691260603077 3.72912159455067e-05 94.9448265465724 116.772304050978 0.813076587964927 0.41661791242729 -765.776404303833 217.024324027207 -3.52852800134897 0.000462271671450856 STT3B other 0.195033059395 1 1 0.813076587964927 -3.52852800134897 6.4355919161202e-07 17.0530557765857 11.6706599995938 1.46119035060392 0.144680209409364 -104.600651967453 25.051476050331 -4.17542869559061 3.58995366479102e-05 CHCHD4 essential 0.00395338411407264 0.295201889855765 1 1.46119035060392 -4.17542869559061 0.000746299543590061 241.771357004753 521.918876891966 0.46323550978747 0.643426178413753 -2890.02984707328 948.529508509048 -3.04685286134744 0.00245263353286276 CLASP2 other 1 1 1 0.46323550978747 -3.04685286134744 0.799799394583632 -3.88502225562167 13.9734489555764 -0.278028872325845 0.781121389658375 -19.2462377401389 28.7905401597734 -0.668491721007377 0.504171903632034 EFHB other 1 1 1 -0.278028872325845 -0.668491721007377 0.0161826969643555 71.2228408257008 55.186289861236 1.29058940191102 0.197528490743973 -130.593625370898 92.012016013257 -1.41931055343991 0.156521381318469 RYBP other 1 1 1 1.29058940191102 -1.41931055343991 2.7415385511579e-06 151.622386137454 58.580271224465 2.58828412651889 0.00996696603731563 -230.44584552941 96.6361554106265 -2.38467522378347 0.0175198020013581 PPP4R2 essential 0.0160624265862959 1 1 2.58828412651889 -2.38467522378347 3.96835156059872e-08 25.5703493862133 9.90558138023506 2.58140823891818 0.0101638509074444 -67.7488870902475 19.1788668134859 -3.53247601900072 0.000455407271071043 GTPBP8 other 0.000261752468937091 1 1 2.58140823891818 -3.53247601900072 8.14542678640169e-10 41.0127478753531 43.4523703793378 0.943855249260583 0.345763960110371 -450.51537838932 84.1310764351928 -5.35492231264101 1.3847218497803e-07 NEPRO other 5.81909289620537e-06 0.00125261938531126 1 0.943855249260583 -5.35492231264101 0.0641694407800587 15.8889472944867 18.8569197138931 0.84260566071034 0.399908892519594 -59.155311561136 37.4536763800572 -1.57942603446625 0.114960242121474 SPICE1 other 1 1 1 0.84260566071034 -1.57942603446625 0.0403641120630527 27.0947828139756 28.4156259381289 0.953517014651402 0.340854094613706 -90.0581242411985 55.0174173902224 -1.63690206689352 0.102369183352251 CCDC191 other 1 1 1 0.953517014651402 -1.63690206689352 0.0441477674679532 33.17354162813 300.24381910576 0.110488674594313 0.912072439006611 -1037.83506818908 509.026744599269 -2.03886157102829 0.0420637434865552 CADPS other 1 1 1 0.110488674594313 -2.03886157102829 5.72360859975615e-05 42.2079658562769 9.57933241488842 4.40614899120489 1.3247029980617e-05 33.8620581415369 13.6740002050032 2.47638274344526 0.0136488987551705 NKX6-1 other 0.292533635533537 1 0.114547068242395 4.40614899120489 2.47638274344526 0.963585080344061 -7.88378780668193 90.3249377129945 -0.0872825158400052 0.930486840026357 -31.9238702295499 128.934164022199 -0.247598225587855 0.804561308714145 CDS1 other 1 1 1 -0.0872825158400052 -0.247598225587855 7.74148628868872e-06 -479.699718506675 331.988851200957 -1.4449271918963 0.149193355341106 -2090.32361101268 473.896867001408 -4.41092515390373 1.29703340601772e-05 WDFY3 other 0.0435303774012967 0.109184272118572 1 -1.4449271918963 -4.41092515390373 1.19995424756035e-16 47.1806037233299 20.5597744298009 2.29480162267456 0.0222165933496922 -152.730826142848 30.5602076968476 -4.99770249135455 8.40269811121095e-07 COX18 other 9.88882295414488e-13 0.00743218647936608 1 2.29480162267456 -4.99770249135455 2.59888290934839e-05 475.920154112543 251.607987123471 1.89151449265796 0.0592151754068661 -644.130048906935 359.15735235991 -1.79344803795484 0.0735910397393157 PTPN13 other 0.138546447897362 1 1 1.89151449265796 -1.79344803795484 0.531025156753887 -109.635318748217 135.313455953079 -0.810232197352447 0.418246720501279 -251.713101383966 229.407446885727 -1.09723160604002 0.273143012453562 SYNPR other 1 1 1 -0.810232197352447 -1.09723160604002 0.000291245964742887 89.9909011712323 29.9395514399796 3.00575315403903 0.00280148088569928 173.186751847192 42.6454483988907 4.06108408633116 5.78712458873364e-05 ALB other 1 0.468467735457988 1 3.00575315403903 4.06108408633116 2.44266192972152e-09 106.798308305447 35.7356552168432 2.98856443676202 0.00296058327937448 -191.066103889552 60.5854411768726 -3.15366365546065 0.00172328041980309 THOC7 essential 1.71303881131371e-05 1 1 2.98856443676202 -3.15366365546065 0.000134002498470525 25.1024854120778 35.7209129940481 0.702739188560507 0.482591619377006 -190.383994484336 60.5604475377032 -3.14370190817709 0.00178167120280032 ATXN7 other 0.65353018504075 1 1 0.702739188560507 -3.14370190817709 2.37173474355514e-15 119.04858529925 45.6231674551248 2.6093888684153 0.00938163352975695 -416.594751658279 77.3519974006634 -5.38570128319281 1.18111653775213e-07 PSMD6 essential 1.91754754016433e-11 0.00107020969485721 1 2.6093888684153 -5.38570128319281 0.000389390682983034 -0.979689084148993 115.058427958392 -0.00851470945269021 0.993210221401529 -654.643325447784 195.085144570252 -3.3556800385282 0.000860992002300117 PRICKLE2 other 1 1 1 -0.00851470945269021 -3.3556800385282 0.355599775422317 62.6542159513358 126.011263582272 0.497211234695932 0.619290733901738 -183.979874957755 213.656018160769 -0.861103172012299 0.389654520563705 ADAMTS9 other 1 1 1 0.497211234695932 -0.861103172012299 1.06670707704087e-06 -360.785678321947 295.170130561132 -1.22229738366845 0.222252534501131 -1993.08824613615 429.118810888087 -4.64460703088578 4.51198443948905e-06 PPM1K other 0.00645144440194321 0.0388346500706823 1 -1.22229738366845 -4.64460703088578 0.990586076931706 -4.15699442473384 30.5628756062429 -0.136014505908754 0.891872589837435 -2.26791227019269 67.4200719741986 -0.0336385323210662 0.973180789280606 PTX3 other 1 1 1 -0.136014505908754 -0.0336385323210662 0.0975355558514205 7.94440336607873 4.8151777898886 1.64986708959349 0.0996903149002817 -2.45844629883932 7.9436751669314 -0.309484746943524 0.757100663965994 HESX1 other 1 1 1 1.64986708959349 -0.309484746943524 0.629219377905741 -4.27416777849159 5.81740209230774 -0.734721050852451 0.462902569057036 -9.46373803758803 10.3585509061591 -0.913616018622929 0.361421277639548 DCLK3 other 1 1 1 -0.734721050852451 -0.913616018622929 2.05325309165633e-06 16.7417461826453 49.3015010601317 0.339578832746407 0.734337234691105 -342.63612392365 81.3334682026082 -4.21273224289557 3.06744925772514e-05 SLMAP other 0.0121449920371472 0.253279285210365 1 0.339578832746407 -4.21273224289557 0.00368614621910022 540.87152755706 161.177265633821 3.35575569811358 0.000860599919161176 428.047971290043 261.458648645267 1.63715361303957 0.102318244869446 RPL9 essential 1 1 1 3.35575569811358 1.63715361303957 2.93230365205234e-11 237.594876358782 98.568080510492 2.41046467708673 0.0163442171303331 -675.524765806947 159.89523726244 -4.22479604378829 2.91251135123989e-05 SMIM14 other 2.18691206370064e-07 0.240893813861051 1 2.41046467708673 -4.22479604378829 5.23558002520337e-05 55.7550540978735 39.9455792592177 1.39577533063331 0.163492522536765 -196.566224398636 66.9926405410419 -2.93414653924878 0.00352121596825391 RPP14 essential 0.268532899492681 1 1 1.39577533063331 -2.93414653924878 8.30738031265248e-05 -52.6873738543461 108.645951148242 -0.484945580553267 0.627958502270915 -725.153657810271 182.209878702265 -3.97977136571826 8.07820476120603e-05 ABHD6 other 0.415784384648257 0.647387329563051 1 -0.484945580553267 -3.97977136571826 1.57277840378787e-05 14.8630894912733 4.36166236771349 3.4076662149035 0.000715898792838193 33.7198333127033 7.31460583556733 4.60993169976983 5.295654053771e-06 C3orf67 other 0.0857636063585527 0.0454208248191938 1 3.4076662149035 4.60993169976983 0.245300583397446 42.8899211456547 63.4914886503063 0.675522374059941 0.499701233536834 -95.056648237107 104.324307198682 -0.911164912469293 0.362710815611734 RBM47 other 1 1 1 0.675522374059941 -0.911164912469293 0.0230072581579853 120.636689930212 242.456425174386 0.49756029292045 0.619044259077304 -793.088268527754 398.385659556667 -1.99075506234416 0.0471301779054531 APBB2 other 1 1 1 0.49756029292045 -1.99075506234416 0.00494163337048375 13.3916001651933 6.40613943606782 2.09043220161521 0.0371549581511061 -23.313654737422 15.0367168782982 -1.55044847396638 0.121756136816843 IL17RE other 1 1 1 2.09043220161521 -1.55044847396638 0.149463374919808 76.5860152929046 64.3504261905035 1.19013998549409 0.234636046453904 -148.945915843134 151.045594508377 -0.986099040676574 0.324628918955256 IL17RC other 1 1 1 1.19013998549409 -0.986099040676574 0.00156040042072584 48.5711854296059 53.8478453169665 0.902007966032803 0.367548379901064 -367.577442755896 126.393565519177 -2.90819743272553 0.00382001307882483 CRELD1 other 1 1 1 0.902007966032803 -2.90819743272553 0.0123130509921868 -22.161380616472 30.5645693053972 -0.725067655789235 0.468797701110632 -211.69767936626 71.7422372302412 -2.9508095584873 0.00333948425252753 PRRT3 other 1 1 1 -0.725067655789235 -2.9508095584873 0.21187622728858 45.3215106462811 29.2587028707346 1.54899247743525 0.122105745026513 -11.325966138261 63.9008837315862 -0.177242715231222 0.85939967790093 PCOLCE2 other 1 1 1 1.54899247743525 -0.177242715231222 0.00560842166579185 222.737395647689 123.658079499222 1.80123609027173 0.0723533231862044 -480.808261420129 270.068724353966 -1.78031818593684 0.0757170041228189 U2SURP essential 1 1 1 1.80123609027173 -1.78031818593684 2.46912165665669e-05 150.43036221576 32.6265151129884 4.61067820742751 5.27435584549184e-06 182.468665395735 76.5821092993034 2.38265395227753 0.0176140298142711 MTMR14 other 0.131851096465467 1 0.0462824725441909 4.61067820742751 2.38265395227753 0.276130418196232 -3.13569648142805 17.027823360936 -0.184151339543593 0.853980153136845 -31.7256248191759 24.4329837224736 -1.29847525703521 0.194808874487688 CXCL3 other 1 1 1 -0.184151339543593 -1.29847525703521 0.128977722786258 -25.7448812676652 21.139847455047 -1.21783666236999 0.223943195793553 -61.2242783700175 30.3332691334863 -2.01838707527997 0.0441613759443504 CXCL5 other 1 1 1 -1.21783666236999 -2.01838707527997 0.000130515240891314 109.113393830816 33.7530290451525 3.23269931373719 0.00131913131576691 6.5791789998446 48.4317456062134 0.135844349971159 0.892006882799278 MTHFD2L other 0.637436436513178 1 1 3.23269931373719 0.135844349971159 0.943482194201212 -3.61900774486466 47.7478188982724 -0.075794200203679 0.939617516071261 -20.2761389179448 68.5126723008816 -0.295947278612922 0.76741092444539 CXCL1 other 1 1 1 -0.075794200203679 -0.295947278612922 1.38916172018349e-10 14.8229810829639 37.957463234843 0.390515588232386 0.696345189282932 -253.657831934922 53.694739315421 -4.72407232382395 3.11856839467736e-06 RCHY1 other 1.01783879237844e-06 0.0269912094559326 1 0.390515588232386 -4.72407232382395 0.701689223037139 104.835280655252 144.508085227006 0.725463080426039 0.468556293506869 -26.7112141652693 301.625566884758 -0.0885575266087272 0.929474132721489 GYG1 other 1 1 1 0.725463080426039 -0.0885575266087272 0.751403762517106 104.350517947483 138.237665897772 0.754863135671367 0.450737720468979 77.9814502529523 288.53758788473 0.270264442233106 0.787084407383991 HPS3 other 1 1 1 0.754863135671367 0.270264442233106 0.728115520656076 0.0334859070121026 35.5812845573845 0.000941110120914759 0.99924953232739 53.8937605396304 74.2672986653297 0.72567282650863 0.468427801557895 TM4SF18 other 1 1 1 0.000941110120914759 0.72567282650863 0.0249562251306447 130.549357788326 83.9013154683965 1.55598701950628 0.120436725788115 -248.14549111093 176.894531066502 -1.40278780590251 0.161391792725002 TOPBP1 essential 1 1 1 1.55598701950628 -1.40278780590251 0.00105241029848783 132.978891480976 44.6985730921815 2.97501424053816 0.00309254590344632 -78.2918831952371 94.2408719379558 -0.830763569831794 0.406561897704927 RYK other 1 1 1 2.97501424053816 -0.830763569831794 0.129979759869212 63.022578195985 85.1797669078941 0.739877326315439 0.459770808926405 -147.039038870842 136.909716151061 -1.07398541903779 0.283420522362703 SNRK other 1 1 1 0.739877326315439 -1.07398541903779 9.94108211892811e-10 35.5406459121332 86.6168768716236 0.410320103838524 0.681771780383855 -677.46046889117 136.31076627646 -4.96997036548949 9.6237822540028e-07 KIAA1143 other 7.07705636046492e-06 0.00848913832625587 1 0.410320103838524 -4.96997036548949 0.00815269693168309 173.793599068957 55.8821941404356 3.10999955785921 0.0019930155509319 182.655191951366 87.942961921641 2.07697339230075 0.0383863502521361 KIF15 other 1 1 1 3.10999955785921 2.07697339230075 8.54921500714174e-13 97.7013674716326 66.4314709682931 1.47070907880791 0.142087821662597 -532.865810146549 104.544576526137 -5.09702012149171 5.14242171881055e-07 ZDHHC3 other 6.59229969200699e-09 0.00457984078277268 1 1.47070907880791 -5.09702012149171 0.166704745709198 -8.56543497235955 20.7709717071526 -0.412375265496607 0.680266149513324 39.788279252102 32.6877067376253 1.21722455391169 0.22417420308212 CDCP1 other 1 1 1 -0.412375265496607 1.21722455391169 0.101719082737006 -76.5604887983697 106.143564391858 -0.721291858220683 0.471114795716788 -340.813699217493 167.040317316138 -2.04030802080239 0.0419189018163473 CLEC3B other 1 1 1 -0.721291858220683 -2.04030802080239 0.0758998305925328 -2.09112598196116 16.5297362883307 -0.12650691732072 0.899388725482676 44.9122398664683 26.0131870507135 1.7265181609201 0.0849593498764315 SLC6A20 other 1 1 1 -0.12650691732072 1.7265181609201 0.00099584905735105 8.27966249636305 59.9143319488358 0.138191685145276 0.890152434653096 -272.124496577493 94.2884203847755 -2.88608606939217 0.00409346597782245 LZTFL1 other 1 1 1 0.138191685145276 -2.88608606939217 0.108737887897361 6.30282222868786 61.1554512383913 0.103062312533983 0.917960685602997 -154.971655207265 96.2415954184417 -1.61023572534802 0.108066814135008 FYCO1 other 1 1 1 0.103062312533983 -1.61023572534802 0.758126178954031 -51.9384928716909 69.9319798878313 -0.742700163144224 0.458061360303511 -54.1972344302712 110.053399637908 -0.49246306437228 0.622638782693914 CCR1 other 1 1 1 -0.742700163144224 -0.49246306437228 0.445742028750482 -40.5809906291844 48.8573144821314 -0.830602153624839 0.406651969686551 -98.7627159355131 77.8009807231503 -1.26942764753768 0.204964199650768 LRRC2 other 1 1 1 -0.830602153624839 -1.26942764753768 3.65261958651978e-09 103.791408148342 41.2363794901046 2.51698644332364 0.0121932181985494 -195.593364434168 64.1881933670669 -3.04718600375067 0.00244997398358012 ELP6 essential 2.54039692242451e-05 1 1 2.51698644332364 -3.04718600375067 0.474346512550302 37.172686496695 152.069009375055 0.244446167233287 0.80699975899747 -277.921944556862 294.431105586828 -0.943928611085224 0.345726509911627 DTX3L other 1 1 1 0.244446167233287 -0.943928611085224 0.000339184147377047 39.8420679886672 76.213495386571 0.522769199688058 0.601399203025602 -485.472177256176 147.562108805226 -3.2899514732266 0.001082981697927 ZNF148 other 1 1 1 0.522769199688058 -3.2899514732266 0.416672036699084 33.8095746177653 30.6997623014537 1.10129760243011 0.271371984949117 -16.7681150923931 67.0481514535874 -0.250090639769546 0.802634511502477 NMNAT3 other 1 1 1 1.10129760243011 -0.250090639769546 3.33940101825023e-27 81.2429273905022 30.2864539046356 2.68248397934983 0.00758419315533346 -152.341978947221 38.8907576985263 -3.9171769325799 0.000103901220261492 SMIM12 other 2.98976573163943e-23 0.825599096197817 1 2.68248397934983 -3.9171769325799 4.88421099077688e-39 35.6944081072989 20.0353158227738 1.78157451687014 0.0755114291767479 -162.801815456333 25.7272976073863 -6.32797964017769 6.14788415827744e-10 ZMYM6 other 4.54817727461143e-35 5.77409280145417e-06 1 1.78157451687014 -6.32797964017769 6.49744289498512e-07 180.376464911073 42.4692615903486 4.24722394872211 2.6474343789584e-05 -105.119950365366 86.7711876534913 -1.21146146789126 0.226374773665071 TPRA1 other 0.00399007968181036 1 0.226011472931678 4.24722394872211 -1.21146146789126 3.14049554239881e-12 537.776663146776 485.395466574001 1.10791447423786 0.2685067767897 -1893.1510031679 623.295072375682 -3.03732708162151 0.00252947923383465 GRIK3 other 2.39462785107909e-08 1 1 1.10791447423786 -3.03732708162151 6.47296536461067e-48 215.396050371164 56.757185503772 3.79504460024447 0.000168392424320024 -403.863621000945 72.8817561814214 -5.54135413526019 5.19030483055045e-08 MEAF6 other 6.15384817213536e-44 0.000473874831029257 1 3.79504460024447 -5.54135413526019 3.1316605900223e-81 60.1284259799204 14.8313651781364 4.05413967343739 5.95528561622215e-05 -177.485660399166 19.0449179457413 -9.31931872349462 5.77989964918127e-19 SNIP1 essential 3.07748286181491e-77 5.66372366623272e-15 0.50048220318731 4.05413967343739 -9.31931872349462 3.11213067360889e-15 536.094280445712 189.787596503542 2.82470662109738 0.00494852519194086 -463.829907134513 243.705765390883 -1.90323731730585 0.057664893120342 DNALI1 other 2.5121118797371e-11 1 1 2.82470662109738 -1.90323731730585 0.0366547670961694 -58.901526232103 245.799371638825 -0.239632533799363 0.810727496608836 -1172.79545764251 488.221850043465 -2.40217732479219 0.0167141705527045 KLF15 other 1 1 1 -0.239632533799363 -2.40217732479219 0.845775192036346 -7.28531001589788 24.7049569269852 -0.294892641886785 0.768215935661125 -28.3437201907786 49.0705069574378 -0.57761213299392 0.563823493829957 CFAP100 other 1 1 1 -0.294892641886785 -0.57761213299392 8.75993580818391e-06 661.193152875673 220.673920773646 2.99624509573964 0.00288958013454564 -988.59594957452 450.882076597162 -2.19258205390536 0.0288664856992335 RPN1 essential 0.0489943209751726 1 1 2.99624509573964 -2.19258205390536 0.2511576368713 -6.79860990717015 44.2852631954367 -0.153518561630016 0.878060057007432 43.0960106192019 56.8665927669263 0.757844078962765 0.448951868039608 HEYL other 1 1 1 -0.153518561630016 0.757844078962765 0.0109971925366938 160.879360264719 55.842129298297 2.88096751120172 0.00416016030055476 49.1261645427505 114.093998785564 0.430576235960328 0.666989289939865 IFT122 other 1 1 1 2.88096751120172 0.430576235960328 4.77989402511856e-12 204.30612927689 27.5152246520197 7.42520302344301 5.94722350283325e-13 150.877938618013 71.7007816183385 2.10427188117883 0.0359253745053341 RFC4 essential 3.62985152267503e-08 1 5.7313392896804e-09 7.42520302344301 2.10427188117883 0.887675770697082 7.21985341901955 17.5735907016517 0.410835414434738 0.681394598827922 -4.32522461652709 44.3481742563834 -0.0975288089994939 0.922351171888597 RPL39L other 1 1 1 0.410835414434738 -0.0975288089994939 6.63665076547671e-12 395.142897727264 169.15875583178 2.33592932144886 0.019946328722988 -1085.90564038826 258.477442702986 -4.20116211702104 3.22066369452003e-05 BAP1 other 5.01929897393003e-08 0.265608134887067 1 2.33592932144886 -4.20116211702104 3.05363335851304e-11 -72.412092413571 322.026966596812 -0.224863442893692 0.822190376248577 -2917.04992080396 496.70472403019 -5.8728048671159 8.48092790930818e-09 TKT essential 2.27556757876391e-07 7.83892166657355e-05 1 -0.224863442893692 -5.8728048671159 0.847434637496084 37.1213208344458 64.9704200077089 0.571357255040699 0.56805055508262 39.719597207009 100.212460096421 0.396353878238216 0.692037006554818 PRKCD other 1 1 1 0.571357255040699 0.396353878238216 3.91899600675023e-08 45.3399708512644 34.0367461409954 1.33208887428445 0.183523682174566 -202.793150334462 52.4993691600241 -3.86277308811701 0.000129036975016045 RFT1 essential 0.000258653736445515 1 1 1.33208887428445 -3.86277308811701 0.00829353896119073 43.7672068094213 20.4618186726615 2.13896953685243 0.0329904993009091 -16.9822865372504 31.5609655438737 -0.53807880223572 0.590795954836092 SFMBT1 other 1 1 1 2.13896953685243 -0.53807880223572 1.73370315635342e-06 243.415421233735 95.0955122961882 2.5596940944551 0.0108111347019477 -312.651451256354 146.678368866936 -2.1315443692995 0.0336003540476681 GNL3 essential 0.0103155337803028 1 1 2.5596940944551 -2.1315443692995 2.68789763626833e-05 203.944460227275 116.692815036374 1.74770366250659 0.0812176968899005 -425.870712002837 178.308596939608 -2.38839135808509 0.0173459452746022 PBRM1 other 0.143079399283678 1 1 1.74770366250659 -2.38839135808509 0.0014482417751156 -31.4175283603424 39.2544752790886 -0.800355326035372 0.423940832814781 -203.320886403591 61.025391507551 -3.33174243344974 0.000936533678186618 UVSSA other 1 1 1 -0.800355326035372 -3.33174243344974 0.000514136384870005 100.955283264673 136.610974630994 0.738998338437796 0.460305650539102 -647.845193244372 225.369291448661 -2.87459391241841 0.00424343818769973 FAM208A other 1 1 1 0.738998338437796 -2.87459391241841 0.780368572565625 76.0055749210715 119.15815690848 0.637854569867574 0.523903195484325 16.7838495514633 196.577101256547 0.0853804916451543 0.9319980940061 ARHGEF3 other 1 1 1 0.637854569867574 0.0853804916451543 8.95340953069095e-06 72.4337466250761 43.1211459869775 1.6797732288226 0.0937161523845427 -180.026396497941 67.0319834038414 -2.68567909461 0.00751387455782112 SLBP essential 0.0500585126860931 1 1 1.6797732288226 -2.68567909461 3.35914866179368e-06 300.472822003184 199.012859464558 1.50981611344917 0.131811383897071 -996.726098391091 318.96452889816 -3.12488069389474 0.00189700097103648 LRPAP1 other 0.0195267311710067 1 1 1.50981611344917 -3.12488069389474 4.51587315771532e-06 7.9810680383943 4.55940354569319 1.75046318195133 0.0807450097468761 -23.3734099434877 7.93462694605916 -2.94574780923966 0.00339512630820294 SLC51A other 0.0260023976421248 1 1 1.75046318195133 -2.94574780923966 4.1852314221636e-09 379.618219037867 117.733003563506 3.22439934043726 0.00135793785244998 -526.222400935812 198.608745982319 -2.64954294098739 0.00835501468642886 UBXN7 other 2.90496913012375e-05 1 1 3.22439934043726 -2.64954294098739 3.60158689058751e-11 100.74926387316 28.2891807307313 3.56140620798232 0.000409695283514303 -147.220517996946 48.1015850315664 -3.06061677386169 0.00234588959063718 RNF168 essential 2.6813814400424e-07 1 1 3.56140620798232 -3.06061677386169 5.39998992366191e-10 106.56806342016 49.2591730924688 2.16341559814883 0.0310543701001822 -333.84969717859 83.7579683075812 -3.98588580793419 7.88573886551376e-05 PIGX other 3.88848062858081e-06 0.632436257014204 1 2.16341559814883 -3.98588580793419 0.024802675942264 33.5040952282106 28.2481114342049 1.18606496247538 0.236245562216551 -71.1850873302687 50.1933543766095 -1.4182173758732 0.15684494074618 MELTF other 1 1 1 1.18606496247538 -1.4182173758732 0.38595246523849 -78.1657113183281 78.8832935920061 -0.990903241472276 0.322281166510504 -170.10368556365 125.300210204422 -1.35756903588695 0.175301097022563 ABLIM2 other 1 1 1 -0.990903241472276 -1.35756903588695 7.69728117280193e-18 53.7491687269376 11.6721907874125 4.6048912073046 5.41617512183415e-06 -6.56243803835348 14.9891072743317 -0.437813801599206 0.661737082766595 EXO5 other 6.42876923552417e-14 1 0.0475106881687292 4.6048912073046 -0.437813801599206 2.01174875648149e-35 34.7144938928849 8.40202825040299 4.13168021557412 4.31515752372424e-05 -39.0225843073194 10.7896542355245 -3.61666680465431 0.000333160720540136 C1orf50 other 1.85543587810288e-31 1 0.36476026548041 4.13168021557412 -3.61666680465431 2.04353771361316e-24 31.9440182555456 37.5277382304801 0.851210857935495 0.395117352994353 -251.994837772347 48.1920921568831 -5.22896654812185 2.64562812291441e-07 ERMAP other 1.80260461717817e-20 0.00237630318000172 1 0.851210857935495 -5.22896654812185 6.71262813464968e-68 63.7123224935915 11.3417754606248 5.61749108107294 3.44939984252825e-08 -90.5154963336257 14.5647969740198 -6.2146761465391 1.19877158072696e-09 ZNF691 other 6.54481243128344e-64 1.12205019956043e-05 0.00031806915947953 5.61749108107294 -6.2146761465391 3.89349678700105e-09 76.785178050483 53.7365885003197 1.42891799039357 0.153742195548523 -290.979388635209 75.3425875608166 -3.86208382344621 0.000129430293069601 AIMP1 other 2.70520156760833e-05 1 1 1.42891799039357 -3.86208382344621 0.536302186578199 -8.62043556258484 40.1166568757102 -0.214884196090735 0.829957849273498 -54.6068748673822 55.9283341021577 -0.976372276128202 0.329420186904854 SGMS2 other 1 1 1 -0.214884196090735 -0.976372276128202 3.883178106269e-06 35.4719452299474 35.9780963513462 0.985931686978213 0.32471219211442 -152.121270751869 50.6994975878592 -3.00044927443811 0.00285007584151547 METAP1 essential 0.0224680685228724 1 1 0.985931686978213 -3.00044927443811 2.74678103989285e-07 20.7446792677511 70.3686570856398 0.2947999880473 0.76828667095459 -389.047033063179 99.161876863471 -3.92335285866796 0.000101394605745263 DNAJB14 other 0.00172690123978064 0.806289904886334 1 0.2947999880473 -3.92335285866796 2.72457172665488e-05 782.458178300349 198.24396674227 3.94694573135533 9.22188213100056e-05 240.805032765522 279.360792619626 0.86198578729478 0.389168091681827 H2AFZ essential 0.144838232988973 1 0.767629468584486 3.94694573135533 0.86198578729478 0.623813315443523 30.2478791486838 33.666231934122 0.898463457623435 0.369433279133307 41.74921186865 47.4416719569562 0.88001139391818 0.379336812758496 EMCN other 1 1 1 0.898463457623435 0.88001139391818 9.69791429165548e-06 7.29216384737739 5.98951214776721 1.21748878163571 0.224073816113177 -24.0489993891708 8.72091020794792 -2.75762492856002 0.00606581446713929 SLC9B1 other 0.0540076846902294 1 1 1.21748878163571 -2.75762492856002 4.59612842502155e-10 38.7280056123702 48.2685183276233 0.802345026410451 0.422788519702416 -316.857527613311 70.2804174732014 -4.50847531937515 8.39283207282838e-06 SLC9B2 other 3.31886433570806e-06 0.0713558582831869 1 0.802345026410451 -4.50847531937515 2.43497844691319e-05 138.445330785188 101.837409788822 1.35947419589991 0.174695841983371 -367.009130183226 148.278337979394 -2.47513652489299 0.0136959440856985 BDH2 other 0.130125248203041 1 1 1.35947419589991 -2.47513652489299 1.19331989644795e-15 93.5647831800273 66.7228536730994 1.40228989063383 0.161537028064213 -528.198742256432 93.7942305889423 -5.63146303285208 3.19864829934992e-08 PGRMC2 other 9.69930411832893e-12 0.000293284062567394 1 1.40228989063383 -5.63146303285208 0.0164807924382356 81.3412677817365 28.8010688129157 2.82424476362695 0.00495603267408893 58.5832232418799 44.8314958054272 1.30674255206956 0.191987409817246 CDC25A other 1 1 1 2.82424476362695 1.30674255206956 2.65172199125356e-06 48.2573519847698 30.8920764131879 1.56212717265482 0.11898354748276 -138.765966252409 48.0894798663553 -2.88557843915241 0.00410084415870607 ZNF589 other 0.0155635280402649 1 1 1.56212717265482 -2.88557843915241 7.6695978253209e-05 427.541429587474 590.147463013214 0.724465419887606 0.469169517083865 -2723.09659495021 918.738702905699 -2.96395110637863 0.00320399869828945 PLXNB1 other 0.385627378657135 1 1 0.724465419887606 -2.96395110637863 1.95149590280697e-13 105.145857500459 31.1641707354351 3.37393407298027 0.000807552954461624 -168.406954026497 48.0690175348355 -3.503440732993 0.000506974969112618 CCDC51 other 1.52685039435617e-09 1 1 3.37393407298027 -3.503440732993 2.36621024726976e-08 70.7875889046935 21.2811750990007 3.32630075996215 0.000954720389495071 -63.3801831436702 33.1304299893722 -1.91305042415693 0.0563978279688143 ATRIP essential 0.000158394113952238 1 1 3.32630075996215 -1.91305042415693 0.0444463484886271 670.56184210526 312.584781059042 2.14521589897431 0.0324886467052543 151.235855263158 486.630468310283 0.310781722706947 0.756115426180759 SHISA5 other 1 1 1 2.14521589897431 0.310781722706947 0.155495007354907 176.89579500657 104.930596191722 1.68583617578383 0.0925395350081598 52.3287216069083 147.503950944016 0.354761491282151 0.722939028941414 SPRY1 other 1 1 1 1.68583617578383 0.354761491282151 0.0440242129302077 -169.916529620095 391.399136176749 -0.434125969923867 0.66441122260267 -1376.16686273336 610.299309437068 -2.25490483350328 0.0246335019019982 BSN other 1 1 1 -0.434125969923867 -2.25490483350328 6.43350679600275e-18 159.051026348955 89.6466183397148 1.77419995639136 0.0767262869610238 -889.560227477347 139.783827324007 -6.36382795139397 4.97710347422898e-10 APEH other 5.37519492806029e-14 4.68146352785978e-06 1 1.77419995639136 -6.36382795139397 0.00501261167413981 2.96290650406657 52.1183224768955 0.0568496137875514 0.954690975415234 -181.380532971994 73.2709730867815 -2.4754759672315 0.0136839834970786 INTU other 1 1 1 0.0568496137875514 -2.4754759672315 7.80762825902375e-09 9.69805118572414 51.5869082011694 0.187994425793176 0.850968482947398 -392.239258041791 79.675499668379 -4.92295950040286 1.211411290424e-06 RNF123 other 5.3607175626457e-05 0.0106543622992791 1 0.187994425793176 -4.92295950040286 0.168694115828213 105.815900131406 81.2797591196475 1.30187270825496 0.193644154351383 -24.7827107189761 114.25729040956 -0.216902664417662 0.828385194354631 HSPA4L other 1 1 1 1.30187270825496 -0.216902664417662 6.51338265567812e-10 31.4885676741134 28.7753677831231 1.09428897352206 0.2744296725928 -175.653163131219 40.4503604470383 -4.3424375256483 1.75232703634099e-05 MFSD8 other 4.67270071718348e-06 0.146494540238107 1 1.09428897352206 -4.3424375256483 3.84613674125861e-14 25.0864651773984 14.3946943911358 1.74275774780231 0.0820777421544993 -100.924516613479 20.2350350839967 -4.98761263296732 8.82855555608195e-07 ABHD18 other 3.05229411786283e-10 0.00780091168935401 1 1.74275774780231 -4.98761263296732 0.168825496086357 -229.954788990828 272.651133331009 -0.843403019020847 0.399467680514286 -776.185882728358 417.043463303746 -1.86116304660322 0.0633970783731685 CAMKV other 1 1 1 -0.843403019020847 -1.86116304660322 1.61214319527156e-13 67.7920733944956 26.3471196957711 2.57303546563296 0.0104122636967576 -181.607218189068 40.3001957547816 -4.50636069596562 8.4921273932709e-06 MON1A other 1.26456512237101e-09 0.0721830828428026 1 2.57303546563296 -4.50636069596562 0.378548824652875 2.97306422018351 2.29416348252854 1.29592517831672 0.195690020604701 4.1662927802154 3.5091212438759 1.18727524376263 0.235768490012251 MST1R other 1 1 1 1.29592517831672 1.18727524376263 7.78140440622201e-06 87.3977272727283 61.5441963087324 1.42008073083453 0.156297188675066 -273.546638257574 94.0405738790795 -2.90881506751872 0.00381304739644295 RAD54L2 other 0.0437392741673739 1 1 1.42008073083453 -2.90881506751872 5.79061814052203e-09 243.579119318182 88.2077113257214 2.76142658796266 0.00599741900660055 -385.77510357481 134.78287622799 -2.86219670013761 0.00440931151594196 TEX264 other 3.99726370240236e-05 1 1 2.76142658796266 -2.86219670013761 0.20315965115156 -33.9509943181821 32.6456947978759 -1.03998381803138 0.298922463363538 -89.1961854876896 49.8831743300859 -1.7881016331772 0.0744523157175753 GRM2 other 1 1 1 -1.03998381803138 -1.7881016331772 2.88967452683809e-07 -124.032812500005 63.5448072040299 -1.95189533114421 0.0515889590435293 -519.883496093753 97.0975411966594 -5.35423955835083 1.39110440520468e-07 DUSP7 other 0.00181471560285432 0.00125825393450763 1 -1.95189533114421 -5.35423955835083 0.0105827512115914 73.8134943181829 24.3673524855915 3.029196313462 0.00259744207982756 71.5891542376905 37.2337271277958 1.92269643036213 0.0551678161763506 POC1A other 1 1 1 3.029196313462 1.92269643036213 0.285911209853635 39.1822425915886 49.3092057530458 0.794623275577064 0.427264001873385 -44.8355774431406 74.5952023382349 -0.601051757187331 0.548117141179617 PPM1M other 1 1 1 0.794623275577064 -0.601051757187331 0.000304186544038108 -1158.63390275953 664.726584151002 -1.74302326758807 0.0820312966138098 -3675.02021775862 934.425239332886 -3.93292054095449 9.75410516113153e-05 ETNPPL other 1 0.777304640290572 1 -1.74302326758807 -3.93292054095449 7.02966351119047e-09 143.272438725846 212.759232406882 0.673401746683549 0.501047717869201 -1454.83373850664 321.863184538084 -4.52003773154274 7.97110426186906e-06 WDR82 essential 4.83711146205016e-05 0.0678181550599819 1 0.673401746683549 -4.52003773154274 3.87451518019623e-08 174.814717477003 29.5274288728642 5.92041786739036 6.49244837245589e-09 136.313760090107 41.5075543076868 3.28407111340845 0.00110527247784804 PITX2 other 0.000255756747044753 1 6.06005131085032e-05 5.92041786739036 3.28407111340845 5.4261338392909e-16 -9.3773323571958 162.934429221328 -0.0575527983987825 0.954131154868239 -1505.32916361621 225.220403570439 -6.68380457432851 7.11835150522026e-11 C4orf3 other 4.43098089316495e-12 6.74392621604568e-07 1 -0.0575527983987825 -6.68380457432851 0.00923630334170492 149.726290587467 48.7316828739854 3.07246295956252 0.00225573681988681 125.319658085835 67.3606513736691 1.86042824008115 0.0634964829563849 PRSS12 other 1 1 1 3.07246295956252 1.86042824008115 0.222339256837151 27.4944696175226 22.7874417371942 1.20656236600028 0.228253483967182 -5.30478244524067 31.4985411549651 -0.168413591573731 0.866335834004432 NDST3 other 1 1 1 1.20656236600028 -0.168413591573731 1.95959825210152e-10 1499.04936309716 223.846773396762 6.69676556132499 6.58478198491231e-11 1162.49606469526 304.337658406029 3.81975753767654 0.000152967461606926 HMGB2 other 1.42952692490806e-06 1 6.27332179702596e-07 6.69676556132499 3.81975753767654 3.65480652580722e-13 58.5215981942778 30.1402864315951 1.94164041297668 0.0528244888507627 -156.530866649892 40.9781390059176 -3.81986274748317 0.000152904354726218 SAP30 other 2.84234303512027e-09 1 1 1.94164041297668 -3.81986274748317 1.67970501471673e-13 1387.69248120633 345.929522780942 4.01148901675293 7.09954270073057e-05 -854.455259359314 470.318956753789 -1.81675700519684 0.0699407922563849 SCRG1 other 1.3163848200335e-09 1 0.594515705759178 4.01148901675293 -1.81675700519684 0.0051800239347805 57.8162126609545 17.915943753906 3.22708161261947 0.00134490381304298 65.1553904625691 24.3581637897164 2.67488924965997 0.00775656654551091 HAND2 other 1 1 1 3.22708161261947 2.67488924965997 1.09949825751212e-10 353.414887512614 52.4566009407996 6.73728150841233 5.10610115811183e-11 411.896523476917 72.5095174192556 5.68058564085181 2.45344553710608e-08 MAD2L1 essential 8.08131219271407e-07 0.000225299903672451 4.86866745425963e-07 6.73728150841233 5.68058564085181 0.000853540007711047 710.844158098791 1077.1332522795 0.659940779466659 0.509639497965138 -3643.87874462299 1501.67718592989 -2.42653932467288 0.0156471637735147 ANXA5 other 1 1 1 0.659940779466659 -2.42653932467288 0.43498492297913 -58.1159383468852 49.0974697446014 -1.18368499739797 0.237181255817195 -79.7602604637167 69.0240823825541 -1.15554249633714 0.248499740930475 TMEM155 other 1 1 1 -1.18368499739797 -1.15554249633714 2.04593880492743e-06 26.4861055724037 80.3754053032352 0.329529978386779 0.741913026527578 -369.692718837952 108.63662199572 -3.40302111798465 0.000727858365305621 MAP9 other 0.0121037739699507 1 1 0.329529978386779 -3.40302111798465 0.0759226507510144 -197.190667523529 105.033572696393 -1.87740607561282 0.0611283277692914 -318.330591553173 141.964976609813 -2.24231778256193 0.0254416313540905 GUCY1A3 other 1 1 1 -1.87740607561282 -2.24231778256193 4.44020592112975e-20 64.4486803391995 30.18434211141 2.13516929079721 0.0333039756557728 -208.760990673618 40.8911672167975 -5.10528324043199 4.94355983800365e-07 FBXO8 other 3.79637606256593e-16 0.00440668923959645 1 2.13516929079721 -5.10528324043199 4.15224399318338e-14 109.86542103051 24.2569665558249 4.52923166537195 7.65130271838505e-06 -43.9510151848016 32.861265352262 -1.33747178368396 0.18176596299425 CEP44 other 3.29272948659442e-10 1 0.0667423136124728 4.52923166537195 -1.33747178368396 0.366757466798664 10.4104879560099 8.83593451343019 1.17819885833088 0.239359985217989 3.78947680103762 11.9701689827047 0.316576717213677 0.751716319431443 HPGD other 1 1 1 1.17819885833088 0.316576717213677 0.132173341726852 14.5637904662036 9.04800531973697 1.60961338455833 0.108206037985059 4.15276375522325 12.257464388067 0.338794682468431 0.734927509233984 ASB5 other 1 1 1 1.60961338455833 0.338794682468431 0.488837258093533 -172.43859040326 455.973095024822 -0.378177116774561 0.705482656718406 -659.747182003117 622.172013847793 -1.06039353638384 0.289551312830556 TMEM144 other 1 1 1 -0.378177116774561 -1.06039353638384 0.0195470403597498 213.526892524388 374.185920640016 0.570643845068159 0.568535063689043 -767.376730786819 510.631980598402 -1.50279802273164 0.133615065012896 FAM198B other 1 1 1 0.570643845068159 -1.50279802273164 0.00484103591116149 63.3943509696602 19.8101766979269 3.200090132275 0.00147373373205279 47.5955587181146 26.5895157140446 1.79001224505096 0.0741425696052831 NPY1R other 1 1 1 3.200090132275 1.79001224505096 3.46370658911186e-08 44.7630245286846 7.56902252388805 5.91397692204128 6.73208069241795e-09 37.1152711642124 10.1592553366745 3.65334563747284 0.000290193429342954 NPY5R other 0.000229401287396878 1 6.28103128602594e-05 5.91397692204128 3.65334563747284 1.28873853538715e-09 89.2070221883713 55.7243932037817 1.60086125769275 0.110128624414519 -269.368633294033 75.4528580338243 -3.57002558038662 0.000396445219725444 NAA15 other 9.1397336929657e-06 1 1 1.60086125769275 -3.57002558038662 0.0265341577174547 12.8207397322443 6.80664930211951 1.8835610831679 0.0602881291928615 -0.198434309053642 9.24552463963898 -0.0214627418981592 0.982886320504579 IL15 other 1 1 1 1.8835610831679 -0.0214627418981592 5.95462296676534e-18 70.8544587596307 40.4355868320364 1.75227971969221 0.0804286640335496 -261.505031367102 53.4088692364653 -4.89628473895039 1.37803631553576e-06 ARFIP1 other 4.97746933791915e-14 0.0120977808140885 1 1.75227971969221 -4.89628473895039 1.34064329460272e-08 90.7439954410587 90.6482213311172 1.00105654704014 0.317354716941072 -601.575807930734 146.587230209097 -4.10387594521452 4.85020648950203e-05 ICE1 other 9.10967118682547e-05 0.39504931856994 1 1.00105654704014 -4.10387594521452 0.143440930480423 138.018571211197 80.3703310238821 1.71728260233475 0.0866360413265893 60.5491631162481 107.809436978902 0.561631382307448 0.574655106099086 HHIP other 1 1 1 1.71728260233475 0.561631382307448 1.12983416067661e-20 29.0212397681712 10.2206946072684 2.83945865553333 0.00472987575038935 -63.1123500355491 13.6536302177527 -4.62238606356053 5.00132740592436e-06 ANAPC10 essential 9.71883345014019e-17 0.0429513997620784 1 2.83945865553333 -4.62238606356053 1.10180662866569e-07 106.480105863829 86.6885990887359 1.22830576319309 0.219993320496553 -346.054030009641 115.805639590375 -2.98823124015113 0.00296411383413931 ABCE1 essential 0.000707139494277637 1 1 1.22830576319309 -2.98823124015113 1.47250366021862e-10 113.00208824219 65.7705050533212 1.71812711717171 0.0864817662260575 -295.242293790738 87.8615583127069 -3.36031251278227 0.00084688333116309 OTUD4 other 1.07801992964605e-06 1 1 1.71812711717171 -3.36031251278227 4.04397895290721e-12 51.6513906955669 19.6605996314842 2.62715235871307 0.00891372502509265 -74.9616992355931 26.162991722338 -2.86518071140888 0.00436920877273237 LSM6 other 3.0770635852671e-08 1 1 2.62715235871307 -2.86518071140888 1.28691126572838e-12 60.8468241469824 70.1946366169089 0.866830103830543 0.386510801732179 -415.951419072615 92.7060312987685 -4.48677840314518 9.25742422909293e-06 TMEM184C other 9.88991307712259e-09 0.0785307297353953 1 0.866830103830543 -4.48677840314518 8.01756583807757e-15 49.5068503937011 18.1141201383169 2.73305300040375 0.00652963855137763 -79.5587296587924 23.9233119427239 -3.32557339256656 0.00095680182426013 PRMT9 other 6.4284842889706e-11 1 1 2.73305300040375 -3.32557339256656 0.0133267234374368 -7.61480552070245 91.0145377076849 -0.0836658155113552 0.933360361299446 -510.750646363257 195.341224672058 -2.61465877067533 0.00923965191089459 LMBRD2 other 1 1 1 -0.0836658155113552 -2.61465877067533 0.81178206269156 -68.7365119197005 107.02017861251 -0.642276183901504 0.521029896964859 -86.028943766398 229.693555351927 -0.374537908277784 0.708185423123087 RANBP3L other 1 1 1 -0.642276183901504 -0.374537908277784 0.00621698945715098 45.03199498118 119.718609993079 0.376148662131838 0.706988505844652 -665.929650963844 256.94774132891 -2.59169295483866 0.00986953155092711 NIPBL other 1 1 1 0.376148662131838 -2.59169295483866 0.169403510782761 56.2318339861798 65.8235167664798 0.854281824316252 0.393417987688532 -89.8592821618775 109.205724684777 -0.822844062628191 0.411046480559778 ANKRD33B other 1 1 1 0.854281824316252 -0.822844062628191 5.86352506401551e-05 -100.060021565953 111.919285844978 -0.894037348527655 0.371795147771283 -746.859106113285 185.681764167418 -4.02225339392989 6.79379134413487e-05 CMBL other 0.299189327980972 0.547307830683505 1 -0.894037348527655 -4.02225339392989 0.00176059059836457 52.5660643360317 34.5331107041378 1.5221931434556 0.12868394798409 -153.101979354017 66.5232036557535 -2.30148235413157 0.021834030334709 GRPEL2 other 1 1 1 1.5221931434556 -2.30148235413157 0.00933137579116237 4.63343367083238 11.3756126859202 0.407312889315162 0.683977186173122 -54.5736481585241 21.3736764393929 -2.55331123371653 0.011008272146201 TIGD6 other 1 1 1 0.407312889315162 -2.55331123371653 0.283410563284005 13.0140941647722 76.3773117624295 0.170392147412209 0.864780425356966 -99.0105027326109 100.886219337962 -0.981407603360899 0.326933552763649 ENPP6 other 1 1 1 0.170392147412209 -0.981407603360899 2.56964644302545e-08 351.337805085035 83.0100145411804 4.23247492518797 2.8173497583392e-05 3.49210767507407 109.647306785265 0.0318485494761224 0.974607336827072 CASP3 other 0.00017160098946524 1 0.240235413893584 4.23247492518797 0.0318485494761224 5.20181473548433e-16 107.564214671239 18.4835523033133 5.81945574671581 1.14172782777459e-08 -9.3054143046266 24.4147858675228 -0.381138477114595 0.703285301705749 PRIMPOL other 4.24988263889069e-12 1 0.000106123601591648 5.81945574671581 -0.381138477114595 0.000209817580693251 102.529067095588 24.681592575675 4.15407015496383 3.93303070272651e-05 101.917892156862 52.9775234995785 1.92379494971434 0.0550324945984576 EGFLAM other 0.994745150066703 1 0.333009709599854 4.15407015496383 1.92379494971434 4.23954465117369e-09 279.462936491732 92.2479280105822 3.02947656948646 0.00259508358572142 -210.11429855013 121.864348216859 -1.72416544809504 0.0853851660321719 CFAP97 other 2.94097212451919e-05 1 1 3.02947656948646 -1.72416544809504 0.0274495973502903 33.9859529009057 164.65691681347 0.206404647667528 0.836571858123898 -782.374805721146 350.287877779598 -2.23351950024778 0.0260247696031374 RICTOR essential 1 1 1 0.206404647667528 -2.23351950024778 0.0551054755765174 119.13503510669 56.9314668770475 2.09260434767965 0.036962059460778 0.861537992902944 104.475249493997 0.008246335826673 0.993424222294929 EBF1 other 1 1 1 2.09260434767965 0.008246335826673 1.17130056496282e-05 72.0797858568009 44.8311585474005 1.6078055573913 0.108601640294232 -257.327862984907 82.2699068067204 -3.12784920966856 0.00187891395241542 UBLCP1 other 0.0646557911859477 1 1 1.6078055573913 -3.12784920966856 5.35757277842012e-05 25.8967863833598 35.770068441804 0.723979223732616 0.4694649896028 -120.16467583623 47.1071412236058 -2.5508802426757 0.0110841930942379 TLR3 other 0.274522029166247 1 1 0.723979223732616 -2.5508802426757 1.82050890800518e-06 23.7134645253231 7.86242817060261 3.01604847901657 0.00270997679779703 -8.1329052781025 10.3543697378051 -0.785456332354854 0.432610731418901 KLKB1 other 0.0108065408779188 1 1 3.01604847901657 -0.785456332354854 3.45911374667641e-17 51.9837891310594 30.1329806266174 1.72514593810678 0.0852180136963289 -277.847824798618 46.3459310512432 -5.99508562016826 4.30397417852426e-09 CCDC127 other 2.86898894149341e-13 3.99667042217763e-05 1 1.72514593810678 -5.99508562016826 0.0480429822237365 -9.98231075012574 11.224571520205 -0.889326664466161 0.374323637630505 -46.808599738607 19.228179641705 -2.43437499601269 0.0153225835866122 FOXQ1 other 1 1 1 -0.889326664466161 -2.43437499601269 6.78454434821486e-13 68.1577597406202 34.723555665325 1.96286810018948 0.05029397379996 -188.900417494808 49.0698053031738 -3.84962639096899 0.000135921342958438 SLC35A1 other 5.24513123560491e-09 1 1 1.96286810018948 -3.84962639096899 2.29908393578045e-07 -262.027376268352 336.849795196346 -0.77787601478463 0.437063039764213 -1921.9556518652 450.764038402294 -4.26377325635261 2.46484013090791e-05 GRIK2 other 0.00145187150544535 0.204458488858811 1 -0.77787601478463 -4.26377325635261 0.0590861070232297 -513.590719770917 673.161752985928 -0.762952912123713 0.445904071502657 -1754.39320577899 872.609011238882 -2.01051465568548 0.0449920176574176 FABP7 other 1 1 1 -0.762952912123713 -2.01051465568548 0.899415743141967 22.8321715959629 50.0214108690431 0.456447972963777 0.648294130456212 25.4891914307904 63.504129094308 0.401378489781934 0.688337235731052 TXLNB other 1 1 1 0.456447972963777 0.401378489781934 1.31084146075447e-05 253.051219383073 93.8499798464924 2.69633749306053 0.00728085085758899 -28.1943513093803 119.146204237879 -0.236636588548717 0.813049359743038 CITED2 other 0.0720045214392432 1 1 2.69633749306053 -0.236636588548717 7.15220862665359e-05 68.2822482814261 59.7963749347607 1.14191283929709 0.254115552702522 -355.141318236975 112.065389974053 -3.16905440938724 0.00163678061499044 CREBRF other 0.361186535646006 1 1 1.14191283929709 -3.16905440938724 1.80902944116935e-06 75.9506815798685 38.1593641481843 1.99035500919064 0.0471743677028972 -72.7144954311666 49.4609806948352 -1.47013857003364 0.142243824268159 DCBLD1 other 0.0107533556385767 1 1 1.99035500919064 -1.47013857003364 5.646761107964e-08 228.38362516694 121.835976095091 1.87451713760384 0.0615245064396289 -988.283276450515 239.653529106493 -4.12380022165815 4.45979783010948e-05 SFXN1 other 0.000368846435572208 0.364320884741644 1 1.87451713760384 -4.12380022165815 0.230627524940398 -2.9148543650738 38.1322374299633 -0.0764406854024094 0.939103405360558 48.4347933847573 48.8829083751312 0.990832890159992 0.32231423294651 TMEM200A other 1 1 1 -0.0764406854024094 0.990832890159992 0.66798917823911 2.20002590698436 14.0986695467622 0.156044930316819 0.876069828965679 -7.6869716654353 18.1402742505656 -0.423751678682344 0.671955894851609 DACT2 other 1 1 1 0.156044930316819 -0.423751678682344 6.95726497098439e-12 13.2343901745577 22.1063706340488 0.598668609770512 0.549704787907018 -126.729031840355 29.2848411960837 -4.32746180837419 1.87230582298133e-05 PDSS2 other 5.2576051385729e-08 0.156281367044252 1 0.598668609770512 -4.32746180837419 0.00536488965967736 -77.7360153970279 105.989374229852 -0.733432157344818 0.463689062109477 -335.398291780855 134.583696930688 -2.49211679742746 0.0130688347119198 STXBP5 other 1 1 1 -0.733432157344818 -2.49211679742746 0.972241384904155 25.2191594928118 288.498165281058 0.0874153201918738 0.930381342101389 -115.499378030335 677.328538003252 -0.170521942528546 0.864678419058372 PI16 other 1 1 1 0.0874153201918738 -0.170521942528546 0.677064533506289 -151.961152240379 301.020995752991 -0.504819113564669 0.613939775550349 202.461904983626 547.148494958004 0.370031000449277 0.711538248376049 GALNT10 other 1 1 1 -0.504819113564669 0.370031000449277 3.79317425253609e-08 29.3822306032788 78.6406951817217 0.373626282618469 0.708863153838199 -706.580077912808 142.94065403477 -4.94317087524265 1.09656369909911e-06 SAP30L other 0.000250539159380009 0.00965195367947037 1 0.373626282618469 -4.94317087524265 0.0290821802128531 1844.88544008537 928.044677570641 1.98792739689511 0.0474432718814299 -1388.83524898837 1787.74815905225 -0.776862916600423 0.43765995260445 RPS14 essential 1 1 1 1.98792739689511 -0.776862916600423 0.000736955774379425 33.1314354766189 9.04917472801129 3.66126596871448 0.000281698898190242 9.21107801258994 17.4319683652438 0.528401487404897 0.597488940986132 MYOZ3 other 1 1 1 3.66126596871448 0.528401487404897 9.00752611380949e-10 135.727020728939 82.9108150427236 1.63702432136265 0.102346919238766 -717.393903163413 152.150094885951 -4.71504078719871 3.25741886583196e-06 SLU7 other 6.42326687175755e-06 0.0281669009328489 1 1.63702432136265 -4.71504078719871 0.000647996732779485 187.772948809722 56.9108576127487 3.29942223129771 0.0010483275405697 354.818815967835 104.437429319186 3.39742962155285 0.000742648288931967 PTTG1 other 1 1 1 3.29942223129771 3.39742962155285 0.472494037746142 -8.23172130284721 36.8131463439587 -0.223608197624164 0.823166917473642 -90.2253278447845 75.1777119156124 -1.20016060007337 0.230728673497625 RELL2 other 1 1 1 -0.223608197624164 -1.20016060007337 0.823488953182912 -6.35681268818109 18.710030081708 -0.339754274066928 0.734204444745951 15.5216911920615 43.9269251812889 0.353352553769757 0.723994156197763 KCNK5 other 1 1 1 -0.339754274066928 0.353352553769757 0.215127508864036 -81.7941987193071 66.9856245668994 -1.22107092750353 0.222716047128913 -256.760767849823 157.267118530655 -1.63264114106455 0.103263142728471 KIF6 other 1 1 1 -1.22107092750353 -1.63264114106455 9.76348793507185e-06 279.196148426491 68.1590980384754 4.09624182921093 5.00868216464461e-05 907.988727101926 271.129302644628 3.34891403564754 0.00088191420657992 SLC29A4 other 0.054353337334545 1 0.422181819657894 4.09624182921093 3.34891403564754 1.7094986399645e-06 97.021008403362 71.389353896789 1.35904029252919 0.174833188609821 -689.783667313077 166.396768480778 -4.14541504387906 4.07366289029246e-05 USP49 other 0.0101783549023486 0.333347834312632 1 1.35904029252919 -4.14541504387906 0.870173733823791 -0.0945432717057647 22.3493029860084 -0.00423025593974689 0.996626680145921 -9.87105616414667 29.3575050862592 -0.336236207237066 0.736853771939777 SYTL3 other 1 1 1 -0.00423025593974689 -0.336236207237066 0.301147427510579 -92.9817390273905 60.0217866035786 -1.54913314462797 0.122071934247337 -98.9164541076512 78.8431704829484 -1.25459762084332 0.210293924799062 TAGAP other 1 1 1 -1.54913314462797 -1.25459762084332 0.0341403360570545 8.6192567784141 51.1183736700535 0.168613673706593 0.866178359209221 119.140399682181 67.1478621037714 1.77429922486674 0.0767082602840067 FNDC1 other 1 1 1 0.168613673706593 1.77429922486674 0.147361268601683 -218.411721098803 114.717375005768 -1.90391142656307 0.0575782847548653 -365.008434578477 302.154369517933 -1.20801971244309 0.227693010950326 DLC1 other 1 1 1 -1.90391142656307 -1.20801971244309 0.0836018834703598 7.40443144845785 3.31466223837769 2.23384191690126 0.0259986908666674 7.65174828054875 8.73049682972217 0.876439042334804 0.38127291923921 C8orf48 other 1 1 1 2.23384191690126 0.876439042334804 1.34324462058801e-40 406.839283267395 26.9788827425737 15.0799159160652 1.18306451305872e-41 245.544964910222 101.835377368606 2.41119511956479 0.0163129067470879 DNAAF5 other 1.25593372024979e-36 1 1.16520023891154e-37 15.0799159160652 2.41119511956479 7.86233750199885e-40 1225.90277199979 83.9180887734896 14.608325688979 1.2633244262789e-39 72.8554276508676 316.759975564698 0.230001999214029 0.818198084953914 SUN1 other 7.33870582436573e-36 1 1.24374289767158e-35 14.608325688979 0.230001999214029 0.0170348437422702 20.7258874287868 12.5576414670588 1.65046019852972 0.0995689727350463 -90.9806521698873 47.4004861453945 -1.91940335571278 0.0555856663011229 GPR146 other 1 1 1 1.65046019852972 -1.91940335571278 0.022979216776194 -19.2701178300508 15.2366929859724 -1.26471786547066 0.206648074259955 -153.65958163851 57.5129220465292 -2.67174012675267 0.00782852230687588 GPER1 other 1 1 1 -1.26471786547066 -2.67174012675267 2.24956997214189e-05 53.3539038544389 12.0670591841075 4.42145041641187 1.2386401383243e-05 -23.0718544892424 44.928909971708 -0.513519123962074 0.607847763440328 TMEM184A other 0.120531959107363 1 0.107229076774734 4.42145041641187 -0.513519123962074 1.49901411446829e-15 586.161905526104 68.2034707109633 8.59431198171976 1.51055174462385e-16 542.12289384185 257.44306181884 2.10579725867049 0.035793175769417 MICALL2 other 1.21585034824523e-11 1 1.46931368199562e-12 8.59431198171976 2.10579725867049 1.31087905398497e-27 1240.00978973354 109.476587378061 11.3267121256836 3.02058996143399e-26 -494.372180131097 407.557301849137 -1.21301269266449 0.225781753102961 INTS1 essential 1.17572742351912e-23 1 2.96621934212818e-22 11.3267121256836 -1.21301269266449 3.02588156059761e-07 17.4392830093361 64.2893050546867 0.271262583947697 0.786317171303508 -680.397626861914 136.060682407063 -5.00069244711208 8.287147941275e-07 PHAX other 0.00189589478815644 0.00733246849844012 1 0.271262583947697 -5.00069244711208 0.372634627107582 95.1638475131979 399.350505263205 0.238296549670012 0.811762794495068 -994.915551628433 845.177937753363 -1.17716696944681 0.239769612079011 ALDH7A1 other 1 1 1 0.238296549670012 -1.17716696944681 1.3550965611817e-08 383.001916757943 67.7848305818161 5.65025999874206 2.8928492388076e-08 -361.784611171962 272.860011052229 -1.32589825008367 0.185566031560835 FOXK1 other 9.20381584354608e-05 1 0.000267009984741941 5.65025999874206 -1.32589825008367 0.00038608706596786 24.5428238203277 38.2146068923278 0.642236720882116 0.52105626012938 -102.914836470252 43.0101992287119 -2.39280073833162 0.0171416264144971 FREM1 other 1 1 1 0.642236720882116 -2.39280073833162 2.1785909579532e-07 139.231600756477 27.7502491788835 5.01730992968614 7.66318289164964e-07 24.9470027953367 32.3547193465375 0.771046799329027 0.441099724579137 RPP25L other 0.00137752306271381 1 0.00689763092077384 5.01730992968614 0.771046799329027 0.000195411759592399 408.513641267805 162.606850455281 2.51227817354566 0.0123572153757711 -236.214890622802 188.171463361879 -1.25531728564245 0.210039073626563 FAM219A other 0.93172326973656 1 1 2.51227817354566 -1.25531728564245 0.758781650263194 31.86804059231 62.9980428680395 0.505857628927668 0.613213430781103 -10.9132222100605 72.9024262029693 -0.149696282805139 0.881073780681578 C9orf24 other 1 1 1 0.505857628927668 -0.149696282805139 1.26632516651791e-24 263.276008329846 53.3671154105531 4.93330033494343 1.15129647204547e-06 -226.119500358915 60.0924842922244 -3.76285825128007 0.000190893352799757 SNAPC3 essential 1.11879828461857e-20 1 0.010304103424807 4.93330033494343 -3.76285825128007 1.85129423423554e-06 145.503909662429 32.4120385013862 4.48919341053498 9.16781545447828e-06 16.2713966276665 37.76733281757 0.430832558556974 0.666803522500859 NUDT2 other 0.0109837286917195 1 0.0797508266385066 4.48919341053498 0.430832558556974 3.91732760264757e-31 1328.28886926534 203.842915552603 6.51623759238555 1.98936874451868e-10 -773.416738397885 229.639425610877 -3.36796147412612 0.000824315481618173 PSIP1 og 3.56006732528612e-27 1 1.88751306479933e-06 6.51623759238555 -3.36796147412612 4.67214072496689e-11 33.8903240091522 7.79749216673242 4.34631074767134 1.72378265227083e-05 -8.3657650011069 8.78840844925295 -0.951908988915738 0.341669330652836 CCDC171 other 3.4704661305054e-07 1 0.148297021574859 4.34631074767134 -0.951908988915738 1.54406313076275e-19 301.724368032416 84.0470212473282 3.5899471933041 0.000368414645089983 -523.977302194991 97.9337298898208 -5.3503251921936 1.42265011864697e-07 UBAP1 essential 1.31276247377449e-15 0.001285933442245 1 3.5899471933041 -5.3503251921936 0.331580252818725 126.408374148835 256.081103948996 0.493626324627262 0.621818097106759 -582.074483335333 529.726454005217 -1.09882087053481 0.272451214496833 DIRAS2 other 1 1 1 0.493626324627262 -1.09882087053481 0.594563682750098 4.11696631226329 90.2147021913005 0.0456352037114001 0.963621856001827 -171.757182534947 186.617105104532 -0.920372130082817 0.357886104126195 SYK other 1 1 1 0.0456352037114001 -0.920372130082817 0.780928977859255 1.36060435962195 5.6570139096753 0.240516353918608 0.810042520413619 -6.51710481180046 12.4161009343501 -0.524891416899681 0.599924244527214 NIPSNAP3B other 1 1 1 0.240516353918608 -0.524891416899681 0.0107050398893206 -182.840984053548 305.381274645571 -0.598730175141732 0.549662343869472 -1887.97952087346 636.275502744676 -2.96723591074835 0.00316949356097563 ABCA1 other 1 1 1 -0.598730175141732 -2.96723591074835 0.00916432233890782 192.821347509259 63.070190408212 3.05725012499967 0.00237086760460273 200.787301397683 130.466277297174 1.53899770544026 0.124528597046948 NFIL3 other 1 1 1 3.05725012499967 1.53899770544026 1.21013651829491e-11 44.0933741483169 8.2260725152286 5.36019759936332 1.34873794596812e-07 -40.8482497284484 17.7760533883837 -2.29793693999264 0.0220369023289026 FXN essential 9.10869757320576e-08 1 0.00123180236605269 5.36019759936332 -2.29793693999264 0.0959798393164609 -16.8049965438925 10.8802817284734 -1.54453689373818 0.123182147014013 17.6599264342847 23.5116416160871 0.751114138376516 0.452988247057762 MAMDC2 other 1 1 1 -1.54453689373818 0.751114138376516 0.0171278701573958 -3.57165518794494 4.34928916432686 -0.821204351561601 0.411978669831937 -26.6852116283614 9.39881011816377 -2.83921169731801 0.00473395994780819 TMC1 other 1 1 1 -0.821204351561601 -2.83921169731801 0.133616036457258 -143.397370951191 236.053405198625 -0.60747851034189 0.543849650952444 -981.370560686005 492.422048654288 -1.99294601727915 0.0468902113582125 ALDH1A1 other 1 1 1 -0.60747851034189 -1.99294601727915 0.0418076270142935 25.7903884985084 48.5796499336038 0.530888726735524 0.595765587764 -179.077532778716 92.5994860283257 -1.93389337737725 0.0537716084624879 KDM1B other 1 1 1 0.530888726735524 -1.93389337737725 0.45852942875613 4.68390804597724 14.6995240831432 0.318643516584904 0.750149087246759 38.9492900608522 31.5865778877798 1.23309622838 0.218202754958072 RASEF other 1 1 1 0.318643516584904 1.23309622838 4.35491112751356e-09 41.4557717600242 16.7758095756697 2.47116370587255 0.0138468806067706 -155.685860902214 36.0473636985906 -4.31892501776214 1.94124704744215e-05 GKAP1 other 3.0179534113669e-05 0.161861178815726 1 2.47116370587255 -4.31892501776214 0.0221138246746959 9.67453546015588 10.4094004533501 0.929403715757932 0.353191823236335 -44.8037185669803 22.3674119769689 -2.00308013341523 0.0457843632103995 KIF27 other 1 1 1 0.929403715757932 -2.00308013341523 0.50516169814997 -36.8280781033961 33.5056452751223 -1.0991603892715 0.272301905238417 -58.6534358524713 71.9959400910212 -0.814676991206983 0.415699951894213 C9orf64 other 1 1 1 -1.0991603892715 -0.814676991206983 0.0138397703514905 83.8406084656094 31.3308551535157 2.67597574514979 0.0077305870610532 -4.88425925925929 64.8092445627982 -0.0753636196843274 0.939959812927358 SVEP1 other 1 1 1 2.67597574514979 -0.0753636196843274 0.000687868507703592 154.52861196869 47.8289193625894 3.23086145428489 0.0013272234745533 -78.1809596573842 104.975646139234 -0.744753307387973 0.456820271680618 ANKS6 other 1 1 1 3.23086145428489 -0.744753307387973 0.0106250221236988 3.62344098039776 16.1938473744168 0.223754176300445 0.823053392455708 102.013102518533 35.3146948452479 2.8886870739097 0.00406128964182258 FBP1 other 1 1 1 0.223754176300445 2.8886870739097 0.547643645732658 28.2073003399126 91.8036270076315 0.307256927197089 0.758793851570099 -174.376035592148 201.492009258928 -0.865424074301953 0.387279831391727 TMEM246 other 1 1 1 0.307256927197089 -0.865424074301953 1.52171351402131e-05 217.682986557988 57.3667641661919 3.7945836709102 0.000168695502383905 -139.807932932934 118.665661387346 -1.17816671898516 0.239369849123523 KIAA1958 other 0.0831159921358442 1 1 3.7945836709102 -1.17816671898516 0.000117758670672198 95.6081796603969 40.0822712090666 2.38529845680926 0.0174895629927026 -203.122799238375 84.1871680146619 -2.41275248982124 0.0162424254101076 STRBP other 0.57866610768318 1 1 2.38529845680926 -2.41275248982124 8.00071755575999e-05 161.671257436231 62.1126219014248 2.60287285397176 0.00955825893213409 -322.392877516095 137.284996388802 -2.34834749605887 0.019300722175427 GAPVD1 other 0.401315992596921 1 1 2.60287285397176 -2.34834749605887 0.282271234426197 54.5211593596952 38.1545121565852 1.42895705587695 0.153730972252956 95.2080904312514 78.9259891390987 1.20629581548173 0.228356101772756 CARD19 other 1 1 1 1.42895705587695 1.20629581548173 0.0566367415405194 -70.7267799546119 173.689390665905 -0.407202648840287 0.684058540033285 -840.774360888788 359.291894626095 -2.34008719223616 0.0197284379230787 WNK2 other 1 1 1 -0.407202648840287 -2.34008719223616 8.0046293100544e-07 155.546474147271 28.9513787512451 5.37267932846139 1.2640041374681e-07 147.438473935903 63.134261621922 2.33531635831643 0.0199786283410638 ZNF367 other 0.00488362434206419 1 0.00115479417999085 5.37267932846139 2.33531635831643 1.45965089170218e-17 198.598174879752 40.7239723639521 4.87668965848593 1.51545127384868e-06 -147.779823488445 47.3913470108496 -3.11828704625367 0.00193984752197415 NDUFB6 essential 1.21545129752041e-13 1 0.0135223717165518 4.87668965848593 -3.11828704625367 5.33406909452451e-08 278.36390702645 56.8932870769405 4.89273728638671 1.40179662681528e-06 20.8850512066969 66.2236843268312 0.315371327025897 0.752630625370716 NOL6 essential 0.00034922150361852 1 0.0125166420808336 4.89273728638671 0.315371327025897 0.654059601483981 10.5213336895539 19.626095496009 0.536088988851267 0.592170435071122 21.0539780924391 22.8447400294916 0.921611629865751 0.357240863521757 AQP3 other 1 1 1 0.536088988851267 0.921611629865751 4.68759527340441e-10 67.7218536165409 14.7535151685859 4.59021818479833 5.80981445084349e-06 -33.5782680975493 17.395549123399 -1.93027928347388 0.0542249769365694 TRMT10B other 3.38444378739799e-06 1 0.0508939745893889 4.59021818479833 -1.93027928347388 1.8317809718789e-08 1113.91829939489 209.318210591806 5.3216502102015 1.65185162963862e-07 101.20686742551 244.320946370888 0.414237374767999 0.678904922305517 VCP essential 0.000123516990933794 1 0.00150566276041561 5.3216502102015 0.414237374767999 0.00327522926204453 98.7983722195732 38.7411617009355 2.55021707873018 0.0111073400740292 -22.6180401941475 45.2113939815895 -0.500273010899814 0.617135844363826 PIGO other 1 1 1 2.55021707873018 -0.500273010899814 1.38718552918246e-12 396.236781233521 63.0844319060645 6.28105491737699 8.1625910096554e-10 -14.8611290347036 73.6202782721656 -0.201861897068138 0.840119056138061 STOML2 other 1.06480361220046e-08 1 7.70548591311469e-06 6.28105491737699 -0.201861897068138 1.04489658704304e-07 23.5257245104594 107.551063548766 0.218740045278979 0.82695805031694 -466.37012899496 126.426716859898 -3.68885739168387 0.000254647813601782 SLITRK5 other 0.00067270442273831 1 1 0.218740045278979 -3.68885739168387 0.000549406941282031 109.538801131269 32.566514528789 3.36354082456187 0.000837769927516922 131.589138224606 38.3727752824656 3.4292317210826 0.000663144832143123 MELK other 1 1 1 3.36354082456187 3.4292317210826 0.00106472869753816 -6.53090673881177 25.5064449864252 -0.256049274694596 0.798033550806344 145.772798498458 50.2757412592997 2.89946592227507 0.00392681516926115 ARMC3 other 1 1 1 -0.256049274694596 2.89946592227507 9.05389616766848e-12 149.023282253905 42.0365358207042 3.54508951188379 0.000434941592177099 -267.792560439703 82.8581952319813 -3.23193812862993 0.00132278496400133 OTUD1 other 6.8275431000388e-08 1 1 3.54508951188379 -3.23193812862993 4.03511808153412e-29 646.644547157385 106.187511722267 6.089647800098 2.48548168381907e-09 -1041.07214795778 202.105573349978 -5.15113032610433 3.9294187057589e-07 ARHGAP12 other 3.63927299773563e-25 0.00351486503230134 2.33436439744287e-05 6.089647800098 -5.15113032610433 3.96129245062595e-13 44.4795408934997 46.2075673308582 0.962602955810563 0.336277935950878 -199.329978208399 55.7973167331202 -3.57239361816982 0.000392977795033059 HECTD2 other 3.07713197564624e-09 1 1 0.962602955810563 -3.57239361816982 8.34265278712922e-08 -6.28156169848681 30.1548684035121 -0.208310035196679 0.835084845083603 -169.792818466797 39.9779689662267 -4.24715969463675 2.65176493826048e-05 FBXO33 other 0.00054102103324533 0.219778278083029 1 -0.208310035196679 -4.24715969463675 0.0212875998119227 -43.8648237864485 55.10072947551 -0.796084266106578 0.426419282383206 -178.798904404542 73.0500701747993 -2.44762125452719 0.0147764693656725 LRFN5 other 1 1 1 -0.796084266106578 -2.44762125452719 0.0203228105945255 80.9195691202955 119.337658742901 0.678072370219928 0.498084678988091 -244.331143732171 163.463212312078 -1.49471639689609 0.135710203453768 SPTSSA essential 1 1 1 0.678072370219928 -1.49471639689609 1.31535339109097e-24 168.973317949677 220.937269652201 0.764802236470443 0.444802115731641 -1812.25498422636 285.890370359952 -6.33898575158244 5.77018721628764e-10 MARCH8 other 1.16185165035065e-20 5.42166790842386e-06 1 0.764802236470443 -6.33898575158244 0.00368851246799305 385.896071757677 172.203423380633 2.24093147616877 0.0255331819501167 95.6322270443811 199.711430787756 0.478852045008954 0.632283942676501 TSHR other 1 1 1 2.24093147616877 0.478852045008954 2.17235904752602e-08 76.9324619264706 140.523318103549 0.54747114546342 0.584335219229443 -734.796731011736 188.190322651742 -3.90454047082709 0.000109360039349191 CFL2 other 0.000145808739269947 0.866568951802989 1 0.54747114546342 -3.90454047082709 7.11901847865191e-35 204.229137782144 75.4688034092124 2.70613986914246 0.0070747095243427 -541.885095718357 87.5842757769258 -6.18701348971042 1.41667081429977e-09 SUGT1 essential 6.55234460775122e-31 1.32430387720743e-05 1 2.70613986914246 -6.18701348971042 1.7238952035366e-16 16.2122020633306 102.88233624132 0.157580034198517 0.874860520968776 -569.718722207394 119.303848720281 -4.77535912142409 2.45204547849824e-06 GTF2A1 essential 1.41755902586815e-12 0.0213205354355422 1 0.157580034198517 -4.77535912142409 5.53214517941661e-21 462.31336797359 733.269531574952 0.63048217342484 0.528708721139644 -4902.73892890882 889.053619944799 -5.51455932344466 5.99356946207728e-08 ZCCHC24 other 4.77424128983654e-17 0.000546313856468344 1 0.63048217342484 -5.51455932344466 2.4639540192787e-31 -637.971389335921 854.86554436873 -0.746282726609395 0.455898834558034 -9612.47877439684 1103.59795397979 -8.7101273971489 6.35190654213793e-17 PHYHIPL other 2.24096618053397e-27 6.20073116643504e-13 1 -0.746282726609395 -8.7101273971489 3.90978767968364e-12 -200.262613634245 141.400066412679 -1.41628373108238 0.157406469994358 -1046.07224869977 182.541950618529 -5.7305854635345 1.8694976670839e-08 SLC16A9 other 2.97652136054316e-08 0.00017201248034839 1 -1.41628373108238 -5.7305854635345 0.720734523908058 -27.0172385764572 88.004153384616 -0.306999585103446 0.758992649611036 27.4993580322278 108.994748627156 0.25229984360344 0.800930141863051 GJB2 other 1 1 1 -0.306999585103446 0.25229984360344 6.92200028531804e-10 307.902755982583 228.331027608545 1.34849284044943 0.178211386793119 -905.747559029514 282.79214106188 -3.20287386922581 0.0014620141997014 CRYL1 other 4.96099760448744e-06 1 1 1.34849284044943 -3.20287386922581 0.0580513280115697 86.3127646984061 122.332058301629 0.705561288649195 0.480836931545402 -140.032355559029 157.56569394027 -0.888723630488447 0.374640550436362 REEP3 other 1 1 1 0.705561288649195 -0.888723630488447 0.0504311992451843 63.3837976741201 29.0869817175254 2.17911223273917 0.0298629546855961 32.9012845505599 35.5838252791528 0.924613480772557 0.355683177282372 SKA3 essential 1 1 1 2.17911223273917 0.924613480772557 1.51718112965258e-29 155.15782298472 55.3505443030025 2.80318513464561 0.00528686029773692 -397.38530656327 68.2336635950355 -5.82388934766479 1.12043800681434e-08 MICU2 other 1.37046971441517e-25 0.000103427632409032 1 2.80318513464561 -5.82388934766479 0.00202450844930957 58.6554628139385 16.6683154109792 3.5189796549748 0.000478858939074948 49.6570395253959 21.9491599952138 2.26236628354907 0.0241673245740877 LRR1 essential 1 1 1 3.5189796549748 2.26236628354907 6.73606214072697e-06 108.769510049778 256.646090773135 0.42381128706116 0.671912932213245 -1034.37664455217 337.956534276718 -3.06067952426457 0.00234508833668299 RPL36AL essential 0.0380722232193888 1 1 0.42381128706116 -3.06067952426457 9.57299281826717e-17 56.6143279559828 20.9539317910727 2.7018474871672 0.00716513212849645 -106.861045869672 27.5925425018121 -3.87282345810118 0.000124116691045537 DNAAF2 other 7.90346287076137e-13 0.979280692349286 1 2.7018474871672 -3.87282345810118 1.96623500809554e-08 1618.3314278568 340.724441435351 4.74967813004358 2.7674497737717e-06 2680.7500598403 440.893638750866 6.08026477187416 2.61887132560181e-09 C10orf10 other 0.000132366940744992 2.43843109126785e-05 0.0245334422444861 4.74967813004358 6.08026477187416 7.74585859330845e-18 275.346806141632 102.454463304387 2.68750425565736 0.00747361039396705 -454.354869117835 132.574936339309 -3.42715509932413 0.000667690676010798 ZNF22 other 6.46856651127188e-14 1 1 2.68750425565736 -3.42715509932413 4.31912107245208e-35 241.521877456299 80.2883881586417 3.00817942663235 0.00278072531603639 -742.487395665687 105.725301807709 -7.02279759878206 8.42005472100736e-12 KLHDC2 other 3.9792062440501e-31 8.04031025308993e-08 1 3.00817942663235 -7.02279759878206 2.53963076064275e-34 60.6542155816485 39.0050033875684 1.55503679820164 0.120661193640864 -279.462613393807 45.2307674328993 -6.17859543967267 1.48250373616177e-09 EML5 other 2.33341274287856e-30 1.38510324069594e-05 1 1.55503679820164 -6.17859543967267 2.50771973840523e-32 21.0759067260544 72.7852083607194 0.289563047227994 0.772288502963832 -840.918628588544 95.8449695847554 -8.77373775829645 3.95921818748914e-17 NEMF other 2.29055120905934e-28 3.86776024735814e-13 1 0.289563047227994 -8.77373775829645 1.81636291623782e-07 58.8029718905564 80.4807834790555 0.730646116359682 0.465388669193871 -351.035670172551 105.978651685364 -3.31232436523845 0.00100247246720093 ARF6 other 0.00115357208810264 1 1 0.730646116359682 -3.31232436523845 2.5755105260045e-14 16.3878809439144 33.1050629005359 0.49502642520728 0.620830266516376 -157.734721481083 38.389110905266 -4.10884018310114 4.74906126936587e-05 TTC8 other 2.04907617448918e-10 0.387238455904093 1 0.49502642520728 -4.10884018310114 1.27974372195805e-06 -4.59544528983323 116.662762941662 -0.0393908490932212 0.968596723499216 -387.757823363067 134.521487638511 -2.88249728850054 0.00413949360256645 TMEM63C other 0.00768742053780201 1 1 -0.0393908490932212 -2.88249728850054 0.131359143562207 -36.412322374801 34.9065412073685 -1.04313750705024 0.297460006437408 -73.0488636203915 40.2918998245928 -1.81299129448855 0.0705175608710697 NGB other 1 1 1 -1.04313750705024 -1.81299129448855 0.000119608754699477 2.3281726566124 3.52208380920438 0.661021367671067 0.508946146647399 -7.07480638677668 4.06546862295043 -1.74021915870606 0.0825228812196764 NOXRED1 other 0.58739859432913 1 1 0.661021367671067 -1.74021915870606 6.75261177424503e-10 230.317696602335 661.518844573159 0.348164981983161 0.727883939086479 -3349.298940759 812.417362651925 -4.12263338369097 4.48339879484743e-05 AMER2 other 4.84162264213369e-06 0.366159179575189 1 0.348164981983161 -4.12263338369097 3.10017844015038e-18 196.872221354472 90.5216824426822 2.17486259691573 0.0301747849159438 -456.840662417665 109.460201510872 -4.173577758052 3.61812715417444e-05 KBTBD6 other 2.60228978266223e-14 0.297446233344681 1 2.17486259691573 -4.173577758052 0.957033522407052 35.9689915953005 121.775379887848 0.295371622970318 0.767850616727862 32.61638563759 150.722172701129 0.216400713001039 0.828776622096286 OTX2 other 1 1 1 0.295371622970318 0.216400713001039 2.08240777039778e-50 486.333735424201 33.0845522941307 14.6997224293852 5.31680324860821e-40 39.6324079658679 68.1842652433118 0.581254455473588 0.561370018522598 NUDT5 other 1.98890766150692e-46 1 5.23492447857965e-36 14.6997224293852 0.581254455473588 0.0191227254264034 -31.8820465300385 43.3135122290197 -0.736076224007478 0.46207922629226 -109.810164276588 50.6258538846295 -2.16905307961487 0.0306171960285369 DACT1 other 1 1 1 -0.736076224007478 -2.16905307961487 8.92426004768284e-41 212.066285488269 19.8602803075651 10.6779099893917 8.21948391302777e-24 -116.765214660051 40.6164710372926 -2.87482421978122 0.00423948850775173 BEND7 other 8.34953770061206e-37 1 8.06002592511503e-20 10.6779099893917 -2.87482421978122 2.78827671428387e-46 817.781320297155 69.6235856200619 11.7457512854884 7.24183525422456e-28 -419.763959014335 143.75000805518 -2.92009694255603 0.0036806839960346 ATP5C1 essential 2.64384398048397e-42 1 7.11655150432648e-24 11.7457512854884 -2.92009694255603 2.20064891839751e-46 85.1599902281827 8.51367948421433 10.0027244842941 2.36542485825965e-21 -89.6725161845713 17.4114166988703 -5.15021366356648 3.94033994747185e-07 PRPF18 other 2.08687536931636e-42 0.00352424004901882 2.31551439375037e-17 10.0027244842941 -5.15021366356648 2.71438719704864e-45 119.198928632342 16.0770325321448 7.41423694913925 6.42347333184461e-13 -257.925973769524 33.1938313061152 -7.77029838438705 5.66944897437306e-14 TAF3 other 2.56645309480949e-41 5.48122326842387e-10 6.18901655523228e-09 7.41423694913925 -7.77029838438705 0.905669972135156 30.5462823093914 108.756204170222 0.280869331018405 0.778943552504882 61.6739621594326 141.692534179888 0.435266138165993 0.663584150755016 VSTM4 other 1 1 1 0.280869331018405 0.435266138165993 9.76511018853333e-34 87.0943057354852 71.6803298733921 1.21503773614489 0.225006270433506 -605.236044046639 86.8977834546179 -6.96491924172866 1.21004194911789e-11 VDAC2 other 8.95851208696048e-30 1.15450102365338e-07 1 1.21503773614489 -6.96491924172866 0.478535421603403 -11.8972673282575 13.3335168422605 -0.892282768980288 0.372731326375473 -30.8198352119048 27.5110689408721 -1.12027036383588 0.26321245919116 SOHLH1 other 1 1 1 -0.892282768980288 -1.12027036383588 0.000734741610215844 30.5203156283126 14.5038895470537 2.10428489056665 0.0359229290506713 -3.47326581085839 17.5830085511006 -0.19753535356388 0.843500255915365 COMTD1 other 1 1 1 2.10428489056665 -0.19753535356388 1.00774607428231e-37 -6.93600023533852 22.7037353914298 -0.305500399637177 0.760130531661687 -189.69113358044 25.7533864399737 -7.36567728762872 8.85568930313465e-13 SLC18A2 other 9.35692229971127e-34 8.51563083389428e-09 1 -0.305500399637177 -7.36567728762872 6.60111059600034e-41 -178.365730351224 165.052029591907 -1.0806636597698 0.280442776992387 -1570.60901686879 187.222438400462 -8.38899989919648 6.84224330397455e-16 PDZD8 other 6.17731929573712e-37 6.66502920240161e-12 1 -1.0806636597698 -8.38899989919648 0.000523885980097715 -15.3335531739487 30.2908216945556 -0.506211199173404 0.612963085856898 69.4938169826879 36.7214446267918 1.89245868971031 0.05908903815379 ZNF503 other 1 1 1 -0.506211199173404 1.89245868971031 6.30548910257999e-09 207.535309953257 47.3408491352631 4.38385271375856 1.46225425103454e-05 -220.128719316706 97.0548783001311 -2.26808505839328 0.0238112971845558 QSOX2 other 4.34826528513916e-05 1 0.126207164406791 4.38385271375856 -2.26808505839328 8.13869734944627e-50 104.670053413516 38.0107657029178 2.75369494609999 0.00613841529194962 -255.409363762183 43.0936499252982 -5.92684453985516 6.27128532767779e-09 FAM204A other 7.76594501084163e-46 5.8078373419624e-05 1 2.75369494609999 -5.92684453985516 0.00371314958702188 120.858343225999 136.651754276536 0.88442584484809 0.376951603637476 -670.166382252563 268.796427956592 -2.49321163732425 0.0130274838741097 NSD1 other 1 1 1 0.88442584484809 -2.49321163732425 5.95518500661128e-16 -94.2841876591939 131.541676940275 -0.716762853053807 0.473903328595591 -781.569804201507 152.825947529921 -5.11411718254512 4.72602258616142e-07 PRDX3 other 4.86002648389546e-12 0.00421655735137322 1 -0.716762853053807 -5.11411718254512 7.32020784824676e-26 -412.856098255843 308.452246127676 -1.33847655006199 0.181437079259386 -2902.99095542173 372.871559777372 -7.7854984626744 5.08059174563846e-14 GHITM other 6.50766477709137e-22 4.91394833638152e-10 1 -1.33847655006199 -7.7854984626744 6.63669418479654e-10 214.493611793613 36.2278701565815 5.92067960016818 6.49282479420277e-09 -33.7058353808342 76.34071133954 -0.441518487179416 0.659056062404312 SNAPC4 essential 4.7591733999176e-06 1 6.06005131085032e-05 5.92067960016818 -0.441518487179416 1.18689946614676e-18 522.558312858312 58.8888646578403 8.87363537902306 1.83248309506089e-17 42.4958947583943 124.092799232381 0.342452543751672 0.732174999829384 PMPCA essential 1.00150576953463e-14 1 1.78502178289881e-13 8.87363537902306 0.342452543751672 5.38170251134554e-12 331.444553644556 48.5579220628999 6.82575653083378 2.93374771738345e-11 4.4746723996738 102.323053920361 0.0437308331625489 0.965138935918271 SDCCAG3 other 4.08040684410219e-08 1 2.79967544669903e-07 6.82575653083378 0.0437308331625489 0.00515806080823729 7.23991054286966 15.2898506625445 0.473510873497625 0.636084660201333 -89.3987633266618 32.21878157942 -2.77474066194254 0.00576092122339472 AK8 other 1 1 1 0.473510873497625 -2.77474066194254 0.000481534499384473 28.1739205914787 32.0606940329449 0.878768268788186 0.380008757489132 -214.534450185859 67.5583117932275 -3.17554486622571 0.0016011708403625 SPACA9 other 1 1 1 0.878768268788186 -3.17554486622571 1.596312062629e-05 264.201799354603 89.735210880153 2.9442377943198 0.00340979614242865 -426.909577835871 189.090084863505 -2.25770472388352 0.024455676195886 TSC1 ts 0.0869670811720277 1 1 2.9442377943198 -2.25770472388352 0.0386287677275975 7.86833666925378 3.47754265385388 2.26261399282448 0.0241485238134431 -1.45154916057351 7.32787975961756 -0.198085832217485 0.843069811701415 GFI1B other 1 1 1 2.26261399282448 -0.198085832217485 5.21009278894294e-51 181.393006142525 10.4520589348536 17.3547630445949 1.19257875772069e-51 24.5763466600985 52.6893148185212 0.466438911660691 0.641134862783245 BORCS5 other 4.98241173406613e-47 1 1.17504784998219e-47 17.3547630445949 0.466438911660691 1.30175046675127e-16 318.34004914005 38.3537412646077 8.30010420479657 1.30901501032343e-15 24.3173525798535 80.8204257666222 0.300881272886046 0.763648131016108 FAM69B other 1.07212168441635e-12 1 1.27052996901992e-11 8.30010420479657 0.300881272886046 3.30158854913049e-10 185.174248739217 28.6858046844532 6.45525725271271 2.92054648788076e-10 40.9926384778896 60.4552688044809 0.678065606001428 0.498094802917131 ZMYND19 other 2.39266122155487e-06 1 2.76809396121338e-06 6.45525725271271 0.678065606001428 8.5004627597954e-07 -116.857908091343 162.848460991389 -0.717586812794765 0.47339462124881 -740.15229652303 197.729072317857 -3.74326490205349 0.000205854394199391 STOX1 other 0.00517508172816344 1 1 -0.717586812794765 -3.74326490205349 0.00158008297409971 -221.133913036243 144.072872382171 -1.53487543754703 0.125539740043424 -598.231260978609 185.162482393928 -3.23084489494955 0.00132773448245541 RET other 1 1 1 -1.53487543754703 -3.23084489494955 7.5302643854804e-10 75.7087679729398 135.565332096312 0.558467026947218 0.576810886583662 -573.757842904722 164.602153380396 -3.48572501101347 0.000540302017618552 DDX21 essential 5.38941022068832e-06 1 1 0.558467026947218 -3.48572501101347 5.53350204630627e-12 48.6979629524374 48.4151767233722 1.00584085917275 0.315050018257902 -233.246791507981 62.2231941337328 -3.74855059685102 0.000201811529540682 BMS1 essential 4.19439455110015e-08 1 1 1.00584085917275 -3.74855059685102 5.10386003964349e-06 130.750539189059 121.995594117714 1.07176443653283 0.284420100169065 -207.611316579866 139.267182263183 -1.49074112943226 0.136754223065902 STK32C other 0.0292298064470383 1 1 1.07176443653283 -1.49074112943226 2.87774745337135e-09 192.397040343695 56.8773098334574 3.38266772649856 0.000782490276686916 -128.870172525639 79.0598928594206 -1.63003221816639 0.103815216775901 METTL17 essential 2.01413544261461e-05 1 1 3.38266772649856 -1.63003221816639 4.95153947395899e-08 412.180182866233 213.917231616465 1.92682085380217 0.0546500318709081 -795.740833498967 295.692724156454 -2.6911072491521 0.00739469565521842 ARHGEF40 other 0.000324920020281189 1 1 1.92682085380217 -2.6911072491521 5.61623812879818e-05 126.767740011937 180.053964965847 0.70405414307862 0.481774045946083 -670.668177300723 248.88433247574 -2.69469825854183 0.00731679047791238 ZNF219 other 0.287270580288027 1 1 0.70405414307862 -2.69469825854183 2.82675379682806e-08 -17.29051803354 32.8092750405482 -0.527000917032486 0.598460364853164 95.7853683283566 37.5280245981044 2.55236904564369 0.0110384209234555 CASP7 other 0.000188346605482654 1 1 -0.527000917032486 2.55236904564369 0.10199998376122 -0.740362811791292 7.76046310804994 -0.0954018853621394 0.924039249724709 9.06624554583749 8.82427585848277 1.0274209114986 0.304789357110968 PPP1R36 other 1 1 1 -0.0954018853621394 1.0274209114986 0.776243181566872 20.5357012971268 39.1246498472187 0.52487885201065 0.599934803177665 52.3588919869073 79.1548256944895 0.661474414573215 0.508658330158687 BTNL9 other 1 1 1 0.52487885201065 0.661474414573215 0.428708462467611 -7.74605724299062 13.5104214892033 -0.57333942165911 0.566709140982211 1.36900203357571 15.4422763275914 0.0886528646770592 0.929398313283317 VWA2 other 1 1 1 -0.57333942165911 0.0886528646770592 7.49127751441137e-12 267.597348939214 78.684571761958 3.40088714911949 0.00073327004368188 -319.628373758719 116.57360683955 -2.74185883429557 0.00635949236819564 METTL3 essential 5.65741277888346e-08 1 1 3.40088714911949 -2.74185883429557 1.52122374542714e-11 379.831546169413 328.452028345492 1.15642929070262 0.248135956510068 -2278.79770342944 486.61175578148 -4.68298941888442 3.77719108716758e-06 SALL2 other 1.14243903281578e-07 0.0326160450376921 1 1.15642929070262 -4.68298941888442 2.71626046326584e-23 40.5642523364486 52.5839472045472 0.771418930926904 0.440874622195061 -284.588828314295 60.1029245295572 -4.73502463552071 2.96257664717639e-06 TRUB1 other 2.38188880023782e-19 0.0256648014944891 1 0.771418930926904 -4.73502463552071 5.03061952347924e-23 9.71020924027544 2.39199748673287 4.05945628878491 5.82833640464464e-05 -8.8813113582105 2.86352628788507 -3.10152953572849 0.00204993363251564 ERICH6B other 4.40380433085373e-19 1 0.490104808266568 4.05945628878491 -3.10152953572849 3.45212847608978e-34 13.5223903441644 53.6523974385378 0.252037019588084 0.801130670262849 -428.667759945189 61.5620279292758 -6.96318452078374 1.22353763688094e-11 ZFYVE1 other 3.17043479244085e-30 1.16713255182073e-07 1 0.252037019588084 -6.96318452078374 9.23945427583091e-09 -148.443623677633 291.330312493639 -0.509537172452228 0.610632957195863 -1157.4200717504 330.643250703059 -3.50051020031209 0.000512085603722529 HSPA12A other 6.31793883381318e-05 1 1 -0.509537172452228 -3.50051020031209 5.69689612807347e-10 88.9421404947117 38.0851332727639 2.33535064345744 0.0199757854858166 -93.876763668669 48.1215554055305 -1.95082563058383 0.0517150836460438 FRAT1 other 4.09663800569763e-06 1 1 2.33535064345744 -1.95082563058383 0.00213954938455198 74.4426984802882 55.5444888067797 1.34023554954748 0.180863576937209 -48.4463354531571 66.9831174313388 -0.723261880171779 0.469905061617496 UBTD1 other 1 1 1 1.34023554954748 -0.723261880171779 0.373802203742688 17.2609289617487 27.2172761402538 0.634190169244017 0.526287794897843 -28.5872105126202 44.3055677159824 -0.645228398739328 0.519117016996163 E2F7 other 1 1 1 0.634190169244017 -0.645228398739328 1.5415962712428e-22 3.28798938288071 29.2963404725386 0.112232085299622 0.910690805526205 -174.919309887193 33.0108950637685 -5.29883571921617 1.8502872528097e-07 ISCA2 essential 1.34612186404922e-18 0.00166710881478154 1 0.112232085299622 -5.29883571921617 0.000214106105451209 65.9675922967811 22.0995894002925 2.98501438655272 0.00299445696378448 -18.2754526982987 35.1895563639539 -0.519343083194395 0.603783841159862 OTOGL other 1 1 1 2.98501438655272 -0.519343083194395 0.0287936981539798 -20.5356320859266 36.3681704043384 -0.564659477164046 0.572594460576524 -120.241944420766 48.0736739379452 -2.50120148037735 0.0127413450619659 PACSIN3 other 1 1 1 -0.564659477164046 -2.50120148037735 1.83234701908744e-09 -91.5092891050801 111.687845958255 -0.819330772475309 0.413045353678637 -564.973304811582 130.938608936175 -4.31479537931379 1.97825558680138e-05 TTC7B other 1.29107170964901e-05 0.164808472936423 1 -0.819330772475309 -4.31479537931379 5.136351047785e-08 196.43629908868 57.4821215904803 3.41734601391631 0.000691702473440793 -161.582782166777 75.7525352729387 -2.13303464477578 0.0334797343563672 SLC39A13 other 0.000336636447671829 1 1 3.41734601391631 -2.13303464477578 2.30391867838281e-11 948.39001939758 167.363646950869 5.66664288616983 2.65020210452302e-08 -127.57990912941 220.559370779262 -0.578437944752271 0.563267141694977 PSMC3 essential 1.7212576446198e-07 1 0.000244799168394791 5.66664288616983 -0.578437944752271 0.184753653350534 1.07051340576396 7.7188342616747 0.138688481896708 0.889760353392475 -14.7245934650071 10.0659362834628 -1.46281409402502 0.144238723069244 AGBL2 other 1 1 1 0.138688481896708 -1.46281409402502 0.526337451667015 -15.2907826876869 37.4850027874184 -0.407917341620665 0.68353459401366 11.4752461466329 43.9460003802718 0.261121513842801 0.794122096294629 TC2N other 1 1 1 -0.407917341620665 0.261121513842801 1.8379831389672e-20 37.0943632831844 103.528322545787 0.358301596809691 0.720290639703059 -666.359921598106 122.355530745413 -5.44609563244518 8.6083565646532e-08 CPSF2 essential 1.57625433997827e-16 0.000782585695292623 1 0.358301596809691 -5.44609563244518 3.62575534033427e-07 -226.307348938491 286.229917729134 -0.790648827816286 0.42957682841492 -1272.46507158842 337.77873455193 -3.76715565968466 0.000187686495089981 MOAP1 other 0.00225993330363035 1 1 -0.790648827816286 -3.76715565968466 3.52777537374818e-05 106.631448210883 32.8158869056853 3.24938492497088 0.00124565512153663 30.0952697059901 38.4730783947635 0.782242309731219 0.434494860158078 IFI27L1 other 0.185102373860567 1 1 3.24938492497088 0.782242309731219 0.911462206769488 -29.5423028330362 364.46347440864 -0.0810569642979178 0.935433675000479 -132.786995933036 427.294007419382 -0.310762598181509 0.7561289368918 IFI27 other 1 1 1 -0.0810569642979178 -0.310762598181509 0.02934890424212 -127.289199705545 97.203316056067 -1.3095149925968 0.19104644456733 -275.725928819316 114.102324822758 -2.41647949984908 0.016079313377739 CLMN other 1 1 1 -1.3095149925968 -2.41647949984908 0.0204127891563155 41.8482173398236 32.6694132846297 1.28096017443669 0.200902927877472 -55.5504933561376 49.4491355978311 -1.12338654022041 0.261904559110018 PDZRN4 other 1 1 1 1.28096017443669 -1.12338654022041 0.237708350086994 -16.9768469939395 48.6618448847644 -0.348873887419233 0.727352017932602 -89.971117766063 61.0125346871201 -1.47463333932029 0.14103118739516 NELL1 other 1 1 1 -0.348873887419233 -1.47463333932029 0.157021273071717 -84.4591837714791 48.5570145118542 -1.73938172724479 0.0826701540196178 -164.674475845512 98.8698439312515 -1.66556827944441 0.0965144523856543 PTER other 1 1 1 -1.73938172724479 -1.66556827944441 0.101301496267703 -41.8380893836511 24.4756905461219 -1.7093731964298 0.0880901517574054 -101.308840358999 49.8364186664299 -2.03282745971554 0.0426725676017805 C1QL3 other 1 1 1 -1.7093731964298 -2.03282745971554 0.000132532647996484 77.2974032999713 28.8375290803604 2.68044474561499 0.0076304322640874 -71.6229744018509 58.4310465827307 -1.2257691516862 0.22094572021588 CACNB2 other 0.646891854870838 1 1 2.68044474561499 -1.2257691516862 5.60100093525115e-05 18.2502730627307 4.45020469614634 4.10099631563791 4.90482188887217e-05 7.50967773677735 8.97389281630257 0.836836130150204 0.403141023898465 HACD1 other 0.286547207847449 1 0.41362362988859 4.10099631563791 0.836836130150204 4.74372352283624e-20 195.486746010277 36.2350420648829 5.39496395947979 1.12539529052164e-07 -281.302194829786 73.4200015861387 -3.83141090646468 0.00014608023313096 ARL5B other 4.05398612261585e-16 1 0.00102894891412393 5.39496395947979 -3.83141090646468 0.258017600021172 -19.674863387983 161.139623043273 -0.122098233919161 0.902877219404948 -368.483203226652 262.310689860423 -1.40475862200936 0.160801843046879 KCNC2 other 1 1 1 -0.122098233919161 -1.40475862200936 0.000204053504428811 144.705759242672 88.6044594649308 1.63316564557279 0.103154408579307 -206.741988769268 111.079198327241 -1.86121246716422 0.0633854434496997 ABTB2 other 0.969662253045712 1 1 1.63316564557279 -1.86121246716422 5.92292843664689e-26 43.9709042170729 15.0919320455965 2.91353711931818 0.00375652374585286 -70.0547025849737 18.199909265392 -3.84917867245557 0.000136161799930841 R3HCC1L other 5.26785255155374e-22 1 1 2.91353711931818 -3.84917867245557 0.000728986766125256 627.176825768684 1966.37640827693 0.318950544325468 0.749916410873834 -3895.33637568842 2284.54847760416 -1.70507932480974 0.0888903132207692 HTRA1 other 1 1 1 0.318950544325468 -1.70507932480974 0.246502757683951 -5.40577705625401 4.11005650502946 -1.31525614055159 0.189115103619232 -10.3518407758281 6.32697115078885 -1.63614477276973 0.102530907902947 LIPC other 1 1 1 -1.31525614055159 -1.63614477276973 0.564188169126795 -4.99862338327557 22.8141015257496 -0.219102355516116 0.826672377819023 -38.1531566141628 38.6497873639061 -0.987150492056599 0.324113860463269 TCP11L2 other 1 1 1 -0.219102355516116 -0.987150492056599 0.388557919479146 -290.355667541483 284.909480952265 -1.01911549791539 0.3087132924674 -606.063150571227 446.731408926199 -1.35666115805023 0.175590915018579 SPRED1 other 1 1 1 -1.01911549791539 -1.35666115805023 0.00904130607724684 126.0868525416 55.4878193766211 2.27233389162027 0.0235513889110623 -21.1727457863297 86.9976967546084 -0.2433713371292 0.807831946140326 GPR176 other 1 1 1 2.27233389162027 -0.2433713371292 2.14612034521219e-05 87.8576448539799 203.221766173032 0.432323990232296 0.665719205076613 -982.215841532609 301.10745208395 -3.26201106858943 0.00119294735398464 CMTM5 other 0.11520374013099 1 1 0.432323990232296 -3.26201106858943 0.0146019671705851 -267.456617150577 211.112966354486 -1.26688863203922 0.205868348295515 -1017.35221901664 353.133557184738 -2.88092762162622 0.00415977296245109 SVOP other 1 1 1 -1.26688863203922 -2.88092762162622 8.8781128884938e-37 42.828138163438 44.2818133289649 0.96717218523262 0.333996607287713 -406.446917631061 51.6834313770629 -7.86416278489284 2.97459171938204e-14 AMN other 8.22379596861181e-33 2.88059462104957e-10 1 0.96717218523262 -7.86416278489284 3.01374491267434e-06 22.3024481900769 91.378892766982 0.24406564267471 0.80729452427249 -594.588715139828 151.54023010245 -3.92363608487233 0.000101279495817355 RAB8B other 0.0175912290552802 0.805475830235422 1 0.24406564267471 -3.92363608487233 0.0146041899388758 81.3912385143014 28.6345970740792 2.84240907262421 0.00468711799184271 48.8901902420115 49.7801807736449 0.982121588997832 0.326583366353459 IKBIP other 1 1 1 2.84240907262421 0.982121588997832 3.03835724653722e-11 17.9749830311267 15.7742974821646 1.13951084360178 0.255114358353782 -117.264399301852 24.3262229317737 -4.82049349094336 1.97970978704924e-06 RPUSD2 other 2.26448765584419e-07 0.0172848461507269 1 1.13951084360178 -4.82049349094336 2.18442858656287e-45 44.3256242539278 55.584924993429 0.797439670183378 0.425627812248594 -564.281176396678 67.0318808981919 -8.41810148895731 5.49682757018357e-16 HIF1AN other 2.06603255717116e-41 5.35555910162985e-12 1 0.797439670183378 -8.41810148895731 2.9936020320659e-12 102.155506767834 139.532957888706 0.732124569804615 0.464484097360921 -603.695901599297 168.26786427568 -3.58770763626166 0.000371231563277887 NDUFB8 essential 2.28381899026307e-08 1 1 0.732124569804615 -3.58770763626166 5.09482689593417e-08 94.0515228007286 39.42241514314 2.38573721217318 0.017469961855323 -170.200417561158 61.3645920785038 -2.77359323668965 0.0057814662150787 ZFYVE19 other 0.000334016851297444 1 1 2.38573721217318 -2.77359323668965 0.417968069088502 6.24350657010067 8.59724639894823 0.726221662189941 0.468091673539317 17.6301693835665 13.3823997427425 1.31741464329876 0.18838997113324 SPINT1 other 1 1 1 0.726221662189941 1.31741464329876 0.232717115669132 -58.0187498588116 98.8809698914569 -0.586753446315299 0.557673681490317 -240.800426954617 149.516651073624 -1.61052581920152 0.108008470408146 FBN1 other 1 1 1 -0.586753446315299 -1.61052581920152 0.742568850763736 -0.0664811549482265 16.9176676943287 -0.00392968795400283 0.996866372192609 -18.5557361692748 28.3227657756081 -0.655152689404902 0.512715747916303 AVPR1A other 1 1 1 -0.00392968795400283 -0.655152689404902 3.40307897743899e-09 8.92217872395494 1.63934476742833 5.4425273445996 8.77144925362002e-08 0.4618707130842 2.84993983543018 0.162063320545321 0.871330895558644 DEPDC4 other 2.370584815684e-05 1 0.000803464751631594 5.4425273445996 0.162063320545321 8.05431462004111e-06 332.34907585316 94.2389668497783 3.52666298202251 0.000465237844460301 -539.494558841025 231.354536092308 -2.33189531510103 0.0201587010600375 BRD7 other 0.0452249765915308 1 1 3.52666298202251 -2.33189531510103 0.017952857901981 3223.933942429 2875.91787337569 1.12101043366889 0.262903318689109 -2546.82066083055 3340.37751406779 -0.762434979311403 0.446214604736364 CKB other 1 1 1 1.12101043366889 -0.762434979311403 2.03487812165548e-10 182.457815665737 54.2957987328865 3.36044076933753 0.000846984674957536 -70.233660817818 63.0645495390306 -1.11367894215038 0.266033348249842 TRMT61A other 1.48301917506252e-06 1 1 3.36044076933753 -1.11367894215038 2.66426556026947e-24 -24.760781244178 103.663338435552 -0.238857648401628 0.811327684789511 -798.626200504433 124.850517237304 -6.3966591262612 4.08249653482315e-10 BTRC other 2.34855009137754e-20 3.84326223788251e-06 1 -0.238857648401628 -6.3966591262612 4.12906944972664e-39 90.2517425174263 42.1508950278986 2.14115838958321 0.0328125456988125 -323.857591909252 50.7658843103941 -6.3794336749679 4.5254469452401e-10 POLL other 3.84622819242037e-35 4.25799303077641e-06 1 2.14115838958321 -6.3794336749679 1.37050590888331e-15 91.2196184869465 84.1168645899681 1.08443911850021 0.278772189130625 -439.087146552493 97.7017061688219 -4.49416047856708 8.97074098059722e-06 BAG5 other 1.11243964624059e-11 0.0761436494433092 1 1.08443911850021 -4.49416047856708 0.000487070693394206 94.8979462521904 40.043456698219 2.36987398384144 0.0182265777521193 10.0125486103346 48.2277182675379 0.207609834551804 0.835630117176328 DPCD other 1 1 1 2.36987398384144 0.207609834551804 0.000992687982702712 187.375328182991 107.196104199082 1.7479677044513 0.0811719048244038 -319.11420768326 185.978452581895 -1.71586656009378 0.0868952228114483 LARP6 other 1 1 1 1.7479677044513 -1.71586656009378 7.98233363620879e-13 307.853606294838 82.8094802908666 3.71761307055072 0.000227514181239856 -345.811982805211 107.832194719729 -3.20694560380621 0.00144101334917871 API5 other 6.16156333378957e-09 1 1 3.71761307055072 -3.20694560380621 2.90012671330655e-05 42.5665545917355 26.9062562039325 1.58203186162756 0.114364088978456 -219.766971974238 62.5523725183276 -3.51332752262669 0.000488545385715247 ZNF319 other 0.153880723408045 1 1 1.58203186162756 -3.51332752262669 1.01641167375032e-24 35.3263259905332 25.0325247935093 1.41121705788514 0.15889053022425 -151.997515126666 30.1487846657409 -5.04158017684163 6.77068456571279e-07 HPS6 other 8.98406278427905e-21 0.00600559720978725 1 1.41121705788514 -5.04158017684163 7.71088731669969e-05 -8.87882125720537 9.07430354142662 -0.978457599161322 0.328389402732229 -64.1702024926824 15.7433420132388 -4.07602162480626 5.44266260287832e-05 SENP8 other 0.387549196537327 0.441726496849604 1 -0.978457599161322 -4.07602162480626 4.51686277076815e-25 41.5947368780411 140.026815189982 0.297048367640207 0.766570402369077 -1016.97373217467 168.435310747971 -6.0377703918412 3.33592504117147e-09 NOLC1 essential 4.00013366979228e-21 3.10274388079359e-05 1 0.297048367640207 -6.0377703918412 4.96646009550135e-16 143.472564523347 20.0438524204285 7.15793359050682 3.54206908992916e-12 2.17857416212024 26.2539848526546 0.0829807046186348 0.933905317610232 ALKBH3 other 4.0605777740819e-12 1 3.40215736087695e-08 7.15793359050682 0.0829807046186348 1.65664155289318e-08 7.25021407485975 74.4120835630736 0.0974332894295896 0.922427082449935 -521.606237465354 112.50966267458 -4.63610169176345 4.69830767987744e-06 COPS2 essential 0.000112022101806637 0.0403960494315862 1 0.0974332894295896 -4.63610169176345 0.309885326307997 -466.67934387195 311.65362889988 -1.49742951981436 0.135003453273684 -605.62296448178 528.970259161725 -1.1449092911982 0.252873390715871 GABRB3 other 1 1 1 -1.49742951981436 -1.1449092911982 3.0974738952783e-12 308.376656329295 142.949398604594 2.15724346754533 0.0315299527363234 -440.997391043624 173.567817604224 -2.54077856788638 0.0114046960339703 SGPL1 other 2.36213359253923e-08 1 1 2.15724346754533 -2.54077856788638 3.07553286899982e-06 9.83210572126544 110.126418717516 0.0892801730571629 0.928900246623471 -751.818441322631 179.258563207993 -4.1940447801665 3.32081787470493e-05 FRS2 other 0.0179387625809958 0.273635392875686 1 0.0892801730571629 -4.1940447801665 4.30791591853398e-09 364.413469727742 180.764961007556 2.01595191732157 0.0444178906353884 -1139.40245085652 294.24063331871 -3.87234909742177 0.000124310587000416 CCT2 essential 2.98624731472776e-05 0.98060821825497 1 2.01595191732157 -3.87234909742177 0.00126369232293693 109.364251480122 61.8822306427195 1.7672965299448 0.0778748602917576 251.053991524246 75.1368234213254 3.34129099544807 0.000905354580891367 PCBD1 other 1 1 1 1.7672965299448 3.34129099544807 5.39363546917798e-12 27.5647745453729 10.7658414624172 2.56039201780925 0.0107913146281076 -60.5662730693828 16.2777486309447 -3.72080159502179 0.00022456144335578 FAM227B other 4.08891504918382e-08 1 1 2.56039201780925 -3.72080159502179 0.615012299206358 30.8401587270565 33.0887173617845 0.932044551315097 0.351919635312566 41.40119631722 61.4938135897224 0.673257908404294 0.501202397890579 CYYR1 other 1 1 1 0.932044551315097 0.673257908404294 0.000638615139233507 25.42941776559 6.59251628291467 3.85731588278265 0.000131936490384774 20.4832891892144 10.7309854489313 1.90879852430089 0.0569443768022197 MYRFL other 1 1 1 3.85731588278265 1.90879852430089 3.17890144466853e-23 161.008788035938 109.791788731679 1.46649207464348 0.143233496469787 -608.81156881158 130.987930924275 -4.64784476337395 4.4478183306329e-06 WBP1L other 2.78630711625196e-19 0.038286820190088 1 1.46649207464348 -4.64784476337395 4.92418926529962e-26 38.2061880667737 56.3956532549752 0.677466894372806 0.49846826378512 -387.526487448664 67.283264243427 -5.75962673342683 1.5916086181527e-08 BORCS7 other 4.38105118933707e-22 0.000146571237645682 1 0.677466894372806 -5.75962673342683 0.294919507539731 149.831761398716 97.2725752517483 1.54032892632831 0.124202309086764 180.322802684987 218.085885313129 0.82684306884913 0.408776224507951 C2 other 1 1 1 1.54032892632831 0.82684306884913 0.000186233953076452 153.17394504653 36.5932156164822 4.18585637982406 3.44096181038268e-05 167.696377338687 46.6648589521815 3.59363300573841 0.000363477745956525 PLEKHF1 other 0.891315699423898 1 0.292137657701489 4.18585637982406 3.59363300573841 1.96366887750797e-15 305.392726247531 95.4838138244792 3.19837168222995 0.0014823409882527 -249.148370409156 115.935550228403 -2.14902478073648 0.0321798000663935 ANAPC16 other 1.59037542389371e-11 1 1 3.19837168222995 -2.14902478073648 1.8593952346814e-19 459.694375781267 92.0593207804747 4.99345826021742 8.57935639247035e-07 -227.396284669683 111.234645276797 -2.04429370097625 0.0415219816253598 SMPD1 other 1.58011407043225e-15 1 0.0077119834611916 4.99345826021742 -2.04429370097625 4.15015595103503e-12 940.787818265543 370.104570013762 2.54195136858364 0.0113670669091898 -1299.90754438566 447.194811038991 -2.90680372915221 0.00383674456217737 APBB1 other 3.15619360076214e-08 1 1 2.54195136858364 -2.90680372915221 0.14152137021113 0.529890472264842 25.1083308822339 0.0211041695583111 0.983172169322655 -35.177187610411 30.4387312916255 -1.15567193893161 0.248445386942839 SYNPO2L other 1 1 1 0.0211041695583111 -1.15567193893161 2.07468689245315e-06 -1.95908020256734 7.65779502306265 -0.255828237327751 0.798203569418097 -30.4071664114945 9.28351494516439 -3.27539370498165 0.00113894467046688 NUDT13 other 0.012265548908183 1 1 -0.255828237327751 -3.27539370498165 1.01866504583383e-05 183.978330099129 156.072661242282 1.17879921207678 0.239119568896641 -553.574945988486 195.6608752684 -2.82925723003699 0.00488046006707443 TRIM44 other 0.0565725840084648 1 1 1.17879921207678 -2.82925723003699 6.46205250294515e-16 543.96055768189 124.868419891678 4.3562700493349 1.64953661848715e-05 -296.636500052237 150.981893955979 -1.96471571709602 0.0500788729268533 ILK og 5.26980381615177e-12 1 0.142008607485559 4.3562700493349 -1.96471571709602 3.48123056214601e-19 853.248658505304 153.995809283088 5.54072648130827 5.20771894749025e-08 -255.919011710183 186.200633971456 -1.37442610291764 0.170012241341705 TAF10 essential 2.95312788586846e-15 1 0.000478849757221729 5.54072648130827 -1.37442610291764 1.05367443898426e-07 271.03029166229 550.158595381995 0.492640293066955 0.622513630323067 -2373.02344885227 665.21212312122 -3.56731840321534 0.000400444365585813 TPP1 other 0.000678144868930267 1 1 0.492640293066955 -3.56731840321534 0.170238696082098 34.4132674220163 227.884118382877 0.151012135756636 0.880035666336083 -323.134014923438 275.541052139385 -1.17272548832389 0.241543307030116 DCHS1 other 1 1 1 0.151012135756636 -1.17272548832389 7.37398839090171e-05 184.691159877208 61.2984488520331 3.01298260128947 0.002737633864282 -26.1840039824109 91.2780189461366 -0.286859906522097 0.774355862224052 NETO1 other 0.371649014901446 1 1 3.01298260128947 -0.286859906522097 1.00153906433773e-10 15.0380461665293 5.4416972186728 2.76348454576403 0.00595982933159493 -10.2737015663644 6.59694824743484 -1.55734154354768 0.120111648812307 MSS51 other 7.37232905259003e-07 1 1 2.76348454576403 -1.55734154354768 2.96712026411708e-13 70.9508814181653 32.7516309898012 2.16633124134365 0.0308282902366528 -195.590267880058 48.816495016209 -4.00664299669843 7.24404586899776e-05 CYB5A other 2.31257353385285e-09 0.582348847408729 1 2.16633124134365 -4.00664299669843 4.28011494187221e-14 -728.618272288307 525.24504078307 -1.38719686187238 0.166087191304103 -3730.44694382288 636.752507908335 -5.85855084588046 9.18405868652959e-09 USP54 other 3.3928471144221e-10 8.48331500874738e-05 1 -1.38719686187238 -5.85855084588046 7.5897530971171e-14 54.4537751089703 13.7683433539612 3.95499833996396 8.93330924760903e-05 -49.0308763842617 17.2986901368503 -2.83436930752429 0.00480545391906821 C11orf74 other 5.98679724300597e-10 1 0.744144660325832 3.95499833996396 -2.83436930752429 7.38684826334349e-09 5.29267704682284 1.36864855298866 3.86708263072025 0.000126893067695771 1.41842937142525 1.75169275887986 0.809747807790381 0.418525826635296 WDR88 other 5.07698081139598e-05 1 1 3.86708263072025 0.809747807790381 3.72012564431114e-16 34.4146044148101 27.4402284559127 1.2541661039777 0.210475890430942 -227.657844879497 41.2295779601924 -5.52171174537131 5.87696083021662e-08 ATP9B other 3.04603887756196e-12 0.000535920058107453 1 1.2541661039777 -5.52171174537131 1.46735177552424e-09 189.474353132941 78.2018965948403 2.42288692964311 0.0158031983233578 -226.308336755908 94.6422295377402 -2.39119828285178 0.0172156335276099 PPFIBP2 other 1.03741770529564e-05 1 1 2.42288692964311 -2.39119828285178 0.265881780084002 -22.2327309597763 48.9461338294579 -0.454228541057837 0.649889863181337 -83.1546705341788 59.2360471367155 -1.40378493423539 0.161093123100753 CYB5R2 other 1 1 1 -0.454228541057837 -1.40378493423539 5.99109222168196e-49 145.14078825949 52.0312991828242 2.78948999042872 0.00551044712346722 -459.301989100525 68.6935259421695 -6.6862485627422 7.02829183332022e-11 KIAA0355 other 5.70831266881857e-45 6.65930651207091e-07 1 2.78948999042872 -6.6862485627422 0.0830267753492162 53.2067824499561 37.5601549948342 1.41657515676583 0.157317986610294 -22.9860008677444 59.276999227817 -0.387772680249943 0.698372641499048 SERPINB8 other 1 1 1 1.41657515676583 -0.387772680249943 5.23829205899197e-16 384.279431950169 335.779534230182 1.14443970753363 0.253066343580802 -2073.37828394812 406.290651903057 -5.10318973433541 4.98662376935676e-07 TUB other 4.27863695378464e-12 0.00444407910325075 1 1.14443970753363 -5.10318973433541 2.14991108765147e-13 62.5486653535306 68.701293317386 0.91044378254378 0.363089270515912 -394.219729092478 83.1895231283546 -4.73881462794575 2.91036719861845e-06 RIC3 other 1.68037050610839e-09 0.0252212421432275 1 0.91044378254378 -4.73881462794575 0.391104565028834 67.5622042609066 54.1899871497051 1.24676546008877 0.213149822940802 85.1882703770907 65.6179668771213 1.29824611202321 0.194885947187333 LMO1 other 1 1 1 1.24676546008877 1.29824611202321 3.47280479590341e-05 -236.406449329282 159.639584006414 -1.48087612981868 0.139363514483802 -1301.44386815283 292.584518785467 -4.44809545479436 1.10158652492933e-05 IDH3A other 0.182355566217957 0.0931281248175258 1 -1.48087612981868 -4.44809545479436 0.605601480139005 39.1505197355381 40.6873641054022 0.962227969207273 0.336468444637169 21.4593201102522 74.5678028050847 0.287782652874263 0.773649857382426 CRABP1 other 1 1 1 0.962227969207273 0.287782652874263 0.0185259178086425 9.95092199261734 152.597319454279 0.0652103328433552 0.948036354355186 326.592679646153 178.498664408463 1.82966455647423 0.0679812341411123 PLD4 other 1 1 1 0.0652103328433552 1.82966455647423 1.22515335770797e-07 23.6097036382991 30.464111646896 0.775000561708641 0.438757514133922 -123.774491158957 36.8886057024618 -3.35535834987379 0.000861643765152049 TRIM66 other 0.000784465694940411 1 1 0.775000561708641 -3.35535834987379 2.91121976289626e-07 2711.67992257011 591.663747935142 4.5831436048493 5.98259751238197e-06 811.747993906513 716.438114427803 1.13303295505828 0.257820239931449 RPL27A essential 0.00182649927924112 1 0.052359693428367 4.5831436048493 1.13303295505828 4.98046735761715e-08 116.786343362993 150.541239978639 0.775776414353731 0.438299679942921 -632.587323688561 182.288474645133 -3.47025408446716 0.000571509111009761 ST5 other 0.000326718658659685 1 1 0.775776414353731 -3.47025408446716 0.0355289488972895 -86.6078338990674 45.1288772880377 -1.91912228053643 0.0556183440624513 -240.584708406055 104.156127234719 -2.30984690765134 0.0213607874508026 CDYL2 other 1 1 1 -1.91912228053643 -2.30984690765134 4.64002668963515e-05 27.164546613741 32.4511485033734 0.8370904533908 0.402999264291118 -142.593417724124 49.4898673910394 -2.8812648980737 0.00415585850338115 PRTG other 0.239703778786552 1 1 0.8370904533908 -2.8812648980737 5.7245428154911e-06 96.5431046482988 19.7377428232066 4.89129408124562 1.40944237798656e-06 38.4031488362294 45.5541324393859 0.843022285350916 0.399676103323147 CENPN essential 0.0325840977057754 1 0.012583501550664 4.89129408124562 0.843022285350916 9.42723970448851e-36 149.153846153846 24.0612103382379 6.19893363871275 1.31671168027219e-09 -119.916356370902 29.1410654660245 -4.11502992266059 4.62804310066094e-05 AKIP1 other 8.70511314312469e-32 0.377694597444939 1.23994738931232e-05 6.19893363871275 -4.11502992266059 7.48284245503864e-06 157.672648813028 82.8514707898962 1.9030760384794 0.0576859894515391 -684.01920997119 191.218768375242 -3.57715519131935 0.000386091508257797 ATMIN other 0.0420984716520474 1 1 1.9030760384794 -3.57715519131935 0.032460859106674 0.00184175866540133 7.05762318965667 0.000260960186724127 0.99979190270919 -40.0544425289197 16.2887876475365 -2.45901925886899 0.0143174540940806 C16orf46 other 1 1 1 0.000260960186724127 -2.45901925886899 2.85409732471599e-30 187.174286755165 45.354506006414 4.12691710783256 4.40559138012525e-05 -287.015605026135 54.9405579231706 -5.22411158305855 2.71703421202899e-07 TMEM41B other 2.58524135672774e-26 0.00244006036934023 0.372316527534385 4.12691710783256 -5.22411158305855 0.67608117347237 -6.29149043249196 7.12654031544191 -0.882825347786141 0.377814907997651 -4.13158223488123 16.4478463556919 -0.251192900610447 0.801782775707692 PKD1L2 other 1 1 1 -0.882825347786141 -0.251192900610447 2.84287731915044e-08 67.4200374573346 40.827533313272 1.65133751627895 0.0993897020575956 -221.890858415711 63.470882925221 -3.49594724682079 0.000520792119617889 LEO1 other 0.000189392487001802 1 1 1.65133751627895 -3.49594724682079 3.8085551871845e-07 43.1117642802877 16.540932696451 2.60636839962101 0.00946419509437726 -29.7976933170652 20.0522533233888 -1.48600223807812 0.138001238866879 ZNF143 other 0.00237158731505979 1 1 2.60636839962101 -1.48600223807812 1.3565183535256e-09 196.517982287254 77.1170021192637 2.54830941150089 0.0111657723867452 -337.09895071236 119.134301590393 -2.82957088103285 0.00487576613136403 TMX3 other 9.6000803879007e-06 1 1 2.54830941150089 -2.82957088103285 0.861322235475509 13.9098775974949 107.191490030861 0.129766622270948 0.896810642699068 -44.7631603509611 83.7335509211394 -0.53459049399588 0.593204314552232 MFAP4 other 1 1 1 0.129766622270948 -0.53459049399588 0.616270154980596 86.8624606591177 96.0616222293703 0.904236870492491 0.366369162156949 107.450724003775 116.453649800069 0.922690909114908 0.35667861590292 WEE1 essential 1 1 1 0.904236870492491 0.922690909114908 2.88164374328005e-06 130.162311414745 37.5380670709544 3.46747506121486 0.000577290222367035 -113.735157074502 29.3231827420437 -3.87867708887644 0.000121149267967402 MAPK7 other 0.0168432076794719 0.956473470602636 1 3.46747506121486 -3.87867708887644 3.01724501118532e-25 161.313137439643 59.1730786602519 2.72612378960098 0.00666533335394184 -310.001045224356 71.7352917438284 -4.3214579280083 1.91999614563459e-05 NDST2 other 2.67388252891243e-21 0.160166078468837 1 2.72612378960098 -4.3214579280083 0.354461629347301 -8.12370249635431 5.67951782710633 -1.43035073463151 0.153329354212395 -7.14572431443213 8.83350979339766 -0.808933762633397 0.418992431117302 CCDC68 other 1 1 1 -1.43035073463151 -0.808933762633397 0.0576899690233609 -31.8188758847403 14.9809550338046 -2.12395510252456 0.0342336604575644 -61.8366010272439 34.5756055183796 -1.78844593175304 0.0743951242754055 BEAN1 other 1 1 1 -2.12395510252456 -1.78844593175304 0.297115085395086 -55.895854972213 64.6116470007603 -0.865104939540625 0.387454759597961 -226.694814164407 149.121789201695 -1.52019912970458 0.129182460952829 TK2 other 1 1 1 -0.865104939540625 -1.52019912970458 0.000147009050027507 152.502041520506 77.3677520092752 1.97113186773506 0.0493393415530972 -295.584047386275 141.78585055007 -2.08472175636378 0.0376745689518358 TMED3 other 0.713875946933572 1 1 1.97113186773506 -2.08472175636378 0.000106041295764896 171.335936064205 148.832763806053 1.15119770460942 0.250278946590941 -589.52683128335 239.644040090518 -2.46001040151332 0.0142785255500444 SEC11C other 0.524162124965883 1 1 1.15119770460942 -2.46001040151332 0.527496758965867 -24.9611067841756 87.1334175359708 -0.286469961698346 0.774655848331667 -130.431645829062 130.811467602685 -0.997096418375363 0.31927717168238 GALR1 other 1 1 1 -0.286469961698346 -0.997096418375363 0.0631220871376646 24.7453559273965 13.2180291450197 1.87209119119851 0.061863184690993 -5.39640054830797 23.7909800646939 -0.226825483171931 0.820665756915543 IQCD other 1 1 1 1.87209119119851 -0.226825483171931 0.00187759741645491 16.9870468548501 49.7737649512267 0.341285150349701 0.733052586416908 -138.278950394784 38.8003835346505 -3.56385524569093 0.00040561541773001 NDEL1 other 1 1 1 0.341285150349701 -3.56385524569093 0.00270392697135001 55.5536048483647 73.9287838116617 0.751447568647836 0.452787830982421 -187.699469493024 54.8999275566996 -3.41893838200736 0.000687634193240918 CENPV other 1 1 1 0.751447568647836 -3.41893838200736 0.569306903820082 -6.6759575538873 19.4007506752869 -0.344108208265945 0.730930050502327 36.6499623438874 44.7763644304058 0.818511346557649 0.41351035189183 RRAD other 1 1 1 -0.344108208265945 0.818511346557649 0.000221040318592416 323.559252160319 86.6159012242439 3.73556411221354 0.000212055373173835 -71.1594441886432 199.906963580801 -0.355962808468556 0.722039801907729 FAM96B essential 1 1 1 3.73556411221354 -0.355962808468556 0.945455972992289 -12.0095286001724 42.110480044619 -0.285190968790844 0.775632644640514 -5.29491312957108 31.7784843326827 -0.166619435783647 0.867746389780357 CFAP52 other 1 1 1 -0.285190968790844 -0.166619435783647 0.0254013930642487 -36.7391955890815 23.0644727054915 -1.59289119930039 0.111907621217492 -103.15350325318 37.9009494574986 -2.72166013595131 0.00675507448465419 CHRFAM7A other 1 1 1 -1.59289119930039 -2.72166013595131 0.00573277858580359 42.69799059745 58.9610855997577 0.724172395455783 0.469347407072372 -137.316592443258 73.8048042699247 -1.86053731598628 0.0634810291400579 PLEKHA7 other 1 1 1 0.724172395455783 -1.86053731598628 1.46978889962948e-60 184.7691812801 33.5397560328147 5.50896020529561 6.17453922848174e-08 -156.856882559466 41.8679415226621 -3.74646750842916 0.00020338341215342 ZNF606 other 1.42349054929115e-56 1 0.000567254918920617 5.50896020529561 -3.74646750842916 0.902284442696182 1393.57236767795 4639.59596972056 0.300365026776649 0.764042229782194 -485.839858133606 7015.47378114095 -0.0692526083469436 0.944820370937985 B2M other 1 1 1 0.300365026776649 -0.0692526083469436 9.78193120347646e-08 249.106285572473 111.778164321772 2.22857735304526 0.0263511637189085 -717.080541142435 212.189241611768 -3.37943872976577 0.000791654052228575 ZNF592 other 0.000631228020560336 1 1 2.22857735304526 -3.37943872976577 8.28504229564978e-10 -92.6401043666855 278.769868894308 -0.33231749447717 0.739809604864155 -2234.32439514763 421.524356638733 -5.30058194730265 1.83936058289865e-07 CASC4 other 5.91717720755308e-06 0.00165744782124998 1 -0.33231749447717 -5.30058194730265 6.68030921386524e-06 300.72364696801 100.699593891522 2.9863441881599 0.0029820946366178 -656.365874197838 240.335188641751 -2.73104358087251 0.00656889990605751 AP1G1 other 0.0377838289136218 1 1 2.9863441881599 -2.73104358087251 0.572055331473285 -36.463759575721 57.8869881134094 -0.629912883086661 0.529080042288636 82.7714821026555 125.756103928632 0.658190572996992 0.51076147560386 SLFN5 other 1 1 1 -0.629912883086661 0.658190572996992 0.00317494024798333 -1.335162035464 13.4985317567728 -0.098911649023909 0.921254088029233 -54.8584029712162 20.4123969804453 -2.68750421735231 0.0074755265696592 CATSPER2 other 1 1 1 -0.098911649023909 -2.68750421735231 4.36820128968074e-51 259.763092031707 51.5891869920815 5.03522360357371 6.99239894944534e-07 -203.900104754736 64.7403289958512 -3.14950677448369 0.00174768892953569 ZNF667-AS1 other 4.17818453357963e-47 1 0.00629665525397553 5.03522360357371 -3.14950677448369 3.33282252168219e-14 89.7351281189018 15.8430685519376 5.6639992325178 2.68502459397089e-08 -12.1110242443843 19.7238637900838 -0.6140289941808 0.539515680178398 SAAL1 other 2.64759421122433e-10 1 0.000247962021253211 5.6639992325178 -0.6140289941808 0.0194283485335647 60.963037290933 66.2179029866692 0.920642825297653 0.357746036373608 -350.914178807045 157.915183980007 -2.22216869817581 0.0267843699150327 YPEL4 other 1 1 1 0.920642825297653 -2.22216869817581 1.57279094035773e-05 789.095839721451 512.483471560181 1.53974885730298 0.12434533697653 -2413.8002858535 874.867869815623 -2.75904553034072 0.0060405254066172 PPIB other 0.0857636063585527 1 1 1.53974885730298 -2.75904553034072 1.29128115459509e-09 136.204252697339 39.1595195733966 3.47819008458599 0.000555415538540921 -165.364130045423 66.8497763798761 -2.47366766203878 0.0137524486791279 FAM96A other 9.1564746672338e-06 1 1 3.47819008458599 -2.47366766203878 0.434727413415171 89.9117451404098 71.0116030396147 1.26615568853236 0.206130337840115 28.293181203004 170.68988900262 0.165757804216334 0.868424035886375 FAM111A other 1 1 1 1.26615568853236 0.165757804216334 0.00386903887521497 91.5147511856847 29.7419317497417 3.07696056717901 0.00222269674899272 36.2184235789731 50.7728774059451 0.713341954000271 0.476014946701233 PCLAF other 1 1 1 3.07696056717901 0.713341954000271 1.08980041499575e-06 110.929439222794 31.9308389400269 3.47405338867368 0.000563693036972 -95.908186167073 60.7701857455729 -1.57821117362736 0.115239011349277 KIF7 other 0.00658457410740434 1 1 3.47405338867368 -1.57821117362736 0.0551743470936252 -43.565891057834 41.7386779236986 -1.04377745594807 0.297164095480055 -231.799348245865 96.3316463798235 -2.40626374568446 0.0165298878682097 LDHD other 1 1 1 -1.04377745594807 -2.40626374568446 0.223909576692554 -60.7215712720222 51.9573345824676 -1.16868141447179 0.243167685415228 46.0227598415237 98.8842441425302 0.46542055552538 0.641861639510755 PLIN1 other 1 1 1 -1.16868141447179 0.46542055552538 6.93121805195289e-05 -5.16368646210939 28.1458513516356 -0.183461725765468 0.854520644445953 -206.007760473741 53.5666669397174 -3.84582002657692 0.000137978499167425 PEX11A other 0.350442384706738 1 1 -0.183461725765468 -3.84582002657692 0.000442707384374037 88.7367462977433 54.4566429054544 1.62949351196336 0.10392751902715 -352.669750541638 125.684337127075 -2.80599602625954 0.00523970602312099 TMEM170A other 1 1 1 1.62949351196336 -2.80599602625954 0.0290055195593193 5.43469189918238 10.5173636715816 0.516735188483324 0.605601834795202 -39.0046573379412 20.0164532186643 -1.94862980528296 0.0519778098928164 MESP1 other 1 1 1 0.516735188483324 -1.94862980528296 0.383336187671339 -4.2794508134534 12.348358427139 -0.346560301007146 0.7290881026724 22.4298132850039 23.5011687816779 0.954412671700426 0.340401224547104 ANPEP other 1 1 1 -0.346560301007146 0.954412671700426 0.244276981490042 -6.63411507427799 15.7820113188062 -0.420359290097115 0.674430096224312 -42.2225466010253 26.9430705272592 -1.56710225578437 0.117816247771515 RBPMS2 other 1 1 1 -0.420359290097115 -1.56710225578437 4.27296192170974e-05 64.6228615079857 278.813494471272 0.231778098224884 0.816818861961084 -1131.43919043701 349.578156005994 -3.23658435459454 0.00130172397208735 NAV2 other 0.22185218297517 1 1 0.231778098224884 -3.23658435459454 2.11826139609078e-05 19.5735654950194 33.3029156111373 0.58774329922253 0.557009581971684 -192.780707718686 56.3247188384963 -3.42266613476509 0.000678794494654588 ANKDD1A other 0.113835367425918 1 1 0.58774329922253 -3.42266613476509 3.21512254642075e-09 140.86420176718 24.2087791971779 5.81872388606861 1.14637655249228e-08 69.8739205341576 37.6525780241149 1.85575395367102 0.0641601325905193 C18orf54 other 2.24222646387383e-05 1 0.000106532773023107 5.81872388606861 1.85575395367102 9.78510615956003e-15 215.559887929019 62.5520511236549 3.44608824262042 0.000624032693245869 -452.77630165772 107.501690609879 -4.21180633615179 3.08090333280905e-05 CLPX other 7.82906343826398e-11 0.254359379156715 1 3.44608824262042 -4.21180633615179 6.50611919884684e-05 28.3215258855579 26.2128380390367 1.08044485085441 0.280544162791108 -137.759989830907 45.5769420123056 -3.02258079960064 0.00265472376898624 ZBTB39 other 0.329860243381535 1 1 1.08044485085441 -3.02258079960064 1.54042934485475e-05 9.77343750000045 47.8440600470347 0.204276925712248 0.83823198388017 -269.836805555557 74.4072152810051 -3.62648708914177 0.000321105502986339 CACNG2 other 0.0840612293487239 1 1 0.204276925712248 -3.62648708914177 0.466127573131925 4.56675749318753 16.5663561031528 0.275664573715062 0.782936911373876 -24.7908230447314 28.804353437204 -0.860662368234633 0.389899233056597 TAC3 other 1 1 1 0.275664573715062 -0.860662368234633 0.000762250704634246 184.197547683923 68.5518876051968 2.68697995224802 0.00748707389125785 -96.9898830554198 119.19294666084 -0.813721665354929 0.416250628808181 NEMP1 other 1 1 1 2.68697995224802 -0.813721665354929 0.313893799620262 66.0626702997271 81.943058669173 0.80620215272218 0.420567826125802 -91.9717286155681 142.476523439165 -0.645521987731814 0.518930099910051 NAB2 other 1 1 1 0.80620215272218 -0.645521987731814 1.79823821729609e-21 191.542195292965 114.865954744583 1.66752799573103 0.0961275047267303 -1170.42154281707 173.660024492908 -6.73972922804041 5.04127065250403e-11 VPS39 other 1.55763394382187e-17 4.78214934096532e-07 1 1.66752799573103 -6.73972922804041 0.306892238561988 28.8734676006991 101.369221899676 0.284834657498653 0.775906998345582 250.906742556917 176.26227553572 1.42348521142331 0.155315686329382 STAT6 other 1 1 1 0.284834657498653 1.42348521142331 0.013276258240403 141.132402934336 68.5043382046209 2.06019657489102 0.0399699085688775 -220.421542315262 164.663201277425 -1.33862053333881 0.181388626569364 PATL1 other 1 1 1 2.06019657489102 -1.33862053333881 0.00547714704260777 14.1868867082961 7.44649955012994 1.90517525889712 0.0574367353318484 -14.6871490790782 12.6340665077197 -1.16250370140952 0.24568791245835 ATP23 other 1 1 1 1.90517525889712 -1.16250370140952 1.74302603618029e-08 -278.129098606945 183.694468332203 -1.51408532402817 0.130728757511581 -1609.11739278886 287.54916280336 -5.59597314456189 3.88307463714392e-08 ELFN2 other 0.00011765425744217 0.000355456652284155 1 -1.51408532402817 -5.59597314456189 0.0403606050378914 -23.3006317354142 28.0943318788328 -0.829371270899296 0.407346114510961 135.542177629135 67.5300681119048 2.00713817442811 0.045348875933274 STX3 other 1 1 1 -0.829371270899296 2.00713817442811 1.05712291072305e-08 184.88847140216 31.6768509779499 5.83670616535903 1.0373267903861e-08 -4.92419633804567 76.1413338938776 -0.0646717897654485 0.948464829631322 MRPL16 essential 7.20640688239906e-05 1 9.65128845775226e-05 5.83670616535903 -0.0646717897654485 0.112251254596691 -54.5090093887707 88.07145180299 -0.618918029314467 0.536306701040437 -305.639482659511 151.481190280446 -2.01767283511348 0.0442623401245191 PIP4K2C other 1 1 1 -0.618918029314467 -2.01767283511348 1.53778038350859e-06 -34.4867256637295 180.880786160765 -0.190659972215501 0.848880541733615 -1278.64402760724 293.421319250645 -4.35770662770079 1.64000421618143e-05 MTMR10 other 0.00918054888954626 0.137284752936547 1 -0.190659972215501 -4.35770662770079 0.229917086124339 -444.61165684728 333.433204292101 -1.33343545610947 0.183083577499447 -889.833236685845 534.394522766033 -1.66512417095905 0.0966046974356931 SCG5 other 1 1 1 -1.33343545610947 -1.66512417095905 0.555054704320932 81.7289936676571 76.6904361929747 1.06569994545348 0.287147741001092 57.8611581462251 122.912021126009 0.470752637668418 0.638052273240676 GREM1 other 1 1 1 1.06569994545348 0.470752637668418 0.881113464455333 8.68640782489486 127.154348478819 0.0683138872465839 0.945566943989277 -137.457446174033 305.639651817776 -0.449736954470768 0.653122604413282 MS4A7 other 1 1 1 0.0683138872465839 -0.449736954470768 0.58510509798076 -13.2763395130546 12.8341095844207 -1.03445739073092 0.30149319074418 -8.67445669378051 30.8492224741096 -0.28118882740272 0.778698359247214 MS4A14 other 1 1 1 -1.03445739073092 -0.28118882740272 0.000263671218650011 61.0148830870727 69.5009895339702 0.877899487420253 0.380480667799258 -346.114581839052 122.705976297492 -2.82068235209606 0.0050103867919247 DIS3L other 1 1 1 0.877899487420253 -2.82068235209606 2.48113251432048e-08 0.261374135250827 40.2390178296946 0.00649553963660476 0.994820316588943 -282.262985330239 60.8406337465057 -4.63938272744324 4.62779717432778e-06 CCNDBP1 other 0.000165789274606894 0.0398083112935675 1 0.00649553963660476 -4.63938272744324 8.04982260755284e-07 -6.32133762985325 4.31242864200595 -1.46584167637678 0.143412221291672 -32.0846046375375 6.52031052737592 -4.92071727302378 1.22463291814993e-06 EPB42 other 0.00490878182608572 0.0107681972492924 1 -1.46584167637678 -4.92071727302378 0.00375006118664115 480.02958928086 178.081061915712 2.69556787295027 0.00729803610852822 -32.2970697407772 308.959365423547 -0.104535008014733 0.916792748388703 SMAD3 ts 1 1 1 2.69556787295027 -0.104535008014733 0.00226994626630743 20.6255350345155 9.58286008448725 2.15233603044087 0.0319178600837017 -34.8006447735097 22.6451576394747 -1.53678085741588 0.125070678664185 CCDC178 other 1 1 1 2.15233603044087 -1.53678085741588 0.00310357196839457 -1779.34159757832 1585.85785020987 -1.12200573168827 0.262478946279981 -7679.50892312557 2397.95539123938 -3.20252367962376 0.00146232285404965 MAP1A other 1 1 1 -1.12200573168827 -3.20252367962376 0.0101647953073961 5.8287219073795 26.1640781801293 0.222775741123041 0.823814136321601 -125.734189992603 50.696748561741 -2.48012335227924 0.0135094103834659 RCCD1 other 1 1 1 0.222775741123041 -2.48012335227924 0.000617701004883289 138.853799316943 55.1819506129048 2.51629015963909 0.0122161624667732 -270.229195320587 130.515291514453 -2.07047919201608 0.038992871433102 AKTIP other 1 1 1 2.51629015963909 -2.07047919201608 3.75592938302985e-05 105.866438510887 202.662775112724 0.522377325840931 0.601672342228814 -1639.35088777446 439.346658431545 -3.73133801364711 0.000215592538621412 MAPRE2 other 0.196359988144801 1 1 0.522377325840931 -3.73133801364711 0.610341673329254 41.0661066778669 51.1626123131476 0.802658519985576 0.422612468425422 -15.4028372765876 101.268417029378 -0.152099121605893 0.879179600528222 EVA1C other 1 1 1 0.802658519985576 -0.152099121605893 0.00458116748679958 171.350762162657 76.5645422427368 2.23799107450306 0.0257426183464033 -108.079426172141 131.669019824422 -0.820841731154852 0.412199866079104 MBD6 other 1 1 1 2.23799107450306 -0.820841731154852 0.00323974496898994 320.437300923938 303.415618788958 1.05610021726278 0.291508602830464 -833.397993991012 458.790880131486 -1.81650950374638 0.0699803644669013 PDIA3 other 1 1 1 1.05610021726278 -1.81650950374638 0.000139344083961035 516.177584206046 170.293989232501 3.03109690795552 0.0025814861053845 -732.899172970165 392.465092274692 -1.86742512237802 0.0625114652684311 NUDT21 essential 0.678187656638357 1 1 3.03109690795552 -1.86742512237802 1.09224146659712e-05 36.2833514524648 73.0816173582513 0.4964771274095 0.619806887811297 -423.704888611763 117.103676322504 -3.61820313347702 0.000331247117618473 SGSM1 other 0.0604337203468188 1 1 0.4964771274095 -3.61820313347702 0.430531117001674 11.1107924528294 17.6026544723363 0.63119982672447 0.528239873256045 -15.1622688679252 27.9848821973267 -0.541802133059312 0.588230955059759 DUSP18 other 1 1 1 0.63119982672447 -0.541802133059312 1.62104260970621e-08 24.6297340854081 174.150683504304 0.141427719890628 0.887597229554414 -1219.94415793716 264.456858604437 -4.61301765579048 5.22121184055179e-06 TEF other 0.000109647322120528 0.0448084400156155 1 0.141427719890628 -4.61301765579048 0.379572548871904 -1.33599379417332 2.31613034984769 -0.576821504999136 0.564357046017391 -4.69429654985585 3.49824015192577 -1.34190231258756 0.180324482340593 MEI1 other 1 1 1 -0.576821504999136 -1.34190231258756 0.156175955703483 101.617431342189 59.5271219853073 1.70707784877069 0.08851629658751 -29.0438432075621 131.570371312907 -0.220747596269137 0.825391831089434 PBX3 other 1 1 1 1.70707784877069 -0.220747596269137 0.170764520695865 4.68452575838933 5.65978717455785 0.827685849999349 0.408299161605064 24.0576808063876 13.3612769830981 1.80055250982525 0.072461272055215 GNGT2 other 1 1 1 0.827685849999349 1.80055250982525 1.67247800902838e-05 524.558737236408 112.844995202931 4.64848916243991 4.43183329820714e-06 452.51579313633 268.540482345224 1.68509339517234 0.0926828431037272 PHB essential 0.0909660789110537 1 0.0390134285241175 4.64848916243991 1.68509339517234 1.50504762678883e-10 214.450467722388 65.2256789829672 3.28782269600274 0.00109375272434806 -296.978328181804 107.019834763868 -2.7749839909309 0.00576456820035883 SNRPD1 essential 1.10169486280942e-06 1 1 3.28782269600274 -2.7749839909309 0.0438149884502657 0.0461813173989236 2.4830323163583 0.0185987580969766 0.985169682101358 12.87010410345 5.48818217227044 2.34505774397894 0.0194706983600759 TTC16 other 1 1 1 0.0185987580969766 2.34505774397894 0.118910203206469 159.647005253639 95.3963370582063 1.67351294794716 0.0949403192544075 -213.719331932936 227.017408450498 -0.941422657370958 0.347007233568979 SAMD14 other 1 1 1 1.67351294794716 -0.941422657370958 2.58527457885414e-07 24.377067883628 4.41365189435584 5.52310614137949 5.72045259016708e-08 10.9258414147176 9.75531487528739 1.11998859641071 0.26333238117865 PIP5KL1 other 0.00162691329247291 1 0.000525766797562256 5.52310614137949 1.11998859641071 0.0920360001851176 -21.2261836851127 236.701409779477 -0.089674935628343 0.928586524748882 -1083.68168853394 523.171477745242 -2.0713699707109 0.0389091974530533 FAM102A other 1 1 1 -0.089674935628343 -2.0713699707109 0.00154785152768401 179.409166238739 65.7555650482135 2.72842558811855 0.00662037150168958 -178.841930815555 145.337826434112 -1.23052570141904 0.219162247737043 GOLGA2 other 1 1 1 2.72842558811855 -1.23052570141904 0.00297428554926551 225.460716119697 73.3616143638949 3.07327909935769 0.00224970800670868 -50.2488679333357 162.149280711499 -0.309892635433517 0.756790325712539 TRUB2 other 1 1 1 3.07327909935769 -0.309892635433517 6.03688005972032e-07 318.06198356753 63.5412227324052 5.00560061469077 8.08991338959129e-07 -23.3301433173029 140.443522827646 -0.16611761687247 0.868141218087875 COQ4 essential 0.00371871811678772 1 0.00727606810259841 5.00560061469077 -0.16611761687247 4.2819034213291e-05 254.387575276599 58.5810880087415 4.34248635393456 1.75280408738096e-05 45.7396480089643 129.480265207868 0.35325574855391 0.724067059971898 SLC27A4 other 0.22223078756698 1 0.150758679555636 4.34248635393456 0.35325574855391 6.50558108698792e-06 419.308400634895 90.681201718803 4.62398372195315 4.96472834373991e-06 4.50366462817128 200.430317138643 0.0224699770596879 0.982083316980163 URM1 essential 0.0368411056956126 1 0.0436052090430676 4.62398372195315 0.0224699770596879 0.723741133493133 -121.937432892943 428.417040260708 -0.284623209241957 0.776067654457411 -761.697213015255 946.919114650942 -0.804395223657551 0.421606139476033 CERCAM other 1 1 1 -0.284623209241957 -0.804395223657551 6.32938928889381e-10 183.959513618147 30.5789636459766 6.0158845063525 3.78616296330871e-09 -24.1156629133831 65.9258628012768 -0.365799731526851 0.714691525855682 DOLPP1 other 4.54386857049686e-06 1 3.54640749097182e-05 6.0158845063525 -0.365799731526851 0.271864897735968 267.496929676127 167.41550809227 1.59780257351487 0.110808055468978 203.997845064852 374.95347067254 0.544061759713674 0.586675810844527 CCDC103 other 1 1 1 1.59780257351487 0.544061759713674 6.12516591220523e-07 241.111254109581 48.8976819597201 4.93093423750022 1.16549459287277e-06 -37.0581483778116 108.078016168414 -0.342883314216884 0.731851497289456 ENDOG other 0.0037724896853272 1 0.0104265146278398 4.93093423750022 -0.342883314216884 0.165607127169897 57.7239293106191 104.029853499379 0.554878502361475 0.579262960495324 -211.431679820472 180.502498604543 -1.17135043257042 0.242099151061505 C15orf39 other 1 1 1 0.554878502361475 -1.17135043257042 0.302909696769434 -63.3569005744021 58.2031629593978 -1.08854738046796 0.276954861311755 -154.037905229364 100.98362752529 -1.52537504350186 0.127890611489215 ISLR2 other 1 1 1 -1.08854738046796 -1.52537504350186 0.0207794679214847 68.4067474354443 36.0124399402394 1.89953103841232 0.0581528306621154 -134.452583850533 81.3226398049586 -1.65332291441841 0.0989833140633158 SP2 other 1 1 1 1.89953103841232 -1.65332291441841 0.00535308355641616 235.27525643874 85.9552921142154 2.73718174473901 0.0064508054643738 -116.273400266623 61.0991977340339 -1.90302662847986 0.0576969764870249 CRK other 1 1 1 2.73718174473901 -1.90302662847986 0.000941240722861143 -43.1420156026101 37.6161308073261 -1.14690199860236 0.252052562594054 -234.604718690533 65.2678569675982 -3.59449091161367 0.000362228230614338 FBXO22 other 1 1 1 -1.14690199860236 -3.59449091161367 0.00104451710670404 -42.211188806139 85.4487467108101 -0.493994241354963 0.621559590618464 -528.731751099813 156.608904945525 -3.37612826859193 0.000801148637298038 TBC1D2B other 1 1 1 -0.493994241354963 -3.37612826859193 0.958194548320339 -0.85977963306179 10.3782665784854 -0.0828442424907598 0.934013235902684 6.30229038785257 25.4784101520892 0.247358071019034 0.804747026851907 NOD2 other 1 1 1 -0.0828442424907598 0.247358071019034 0.851796437962998 -1.77877437894267 20.32396622523 -0.08752102612405 0.930297371660362 25.6997755521922 49.8948782523171 0.515078429938823 0.606758056518538 SNX20 other 1 1 1 -0.08752102612405 0.515078429938823 0.12930117431256 36.7055130355064 19.9836370088583 1.83677841121893 0.0669200393359365 17.2043148018129 31.3408042209807 0.54894299075758 0.583324296559069 KATNAL2 other 1 1 1 1.83677841121893 0.54894299075758 1.90377817782564e-20 54.5843183220486 77.0667618651633 0.708273151758338 0.4791523969282 -861.580115316699 120.865600915908 -7.12841460918351 4.2142690943811e-12 HDHD2 other 1.63248978748548e-16 4.0351626578699e-08 1 0.708273151758338 -7.12841460918351 0.387586216909508 -586.130613747097 1562.79825125143 -0.375052002571508 0.707803747005504 902.29418065523 1804.0683815994 0.50014411308251 0.617225363758199 IGF2 other 1 1 1 -0.375052002571508 0.50014411308251 0.024109333267554 155.129492196288 58.6029248369357 2.64712883576955 0.00841118973989897 -24.1772815184633 137.497045689723 -0.175838552728049 0.860502231719313 CDK12 other 1 1 1 2.64712883576955 -0.175838552728049 0.0267759687789424 -18.1615821991883 9.89075350934451 -1.83621826001727 0.067002978368425 27.5244443492628 22.8275694604882 1.20575448897021 0.228563116859546 DPEP2 other 1 1 1 -1.83621826001727 1.20575448897021 0.000245235039521337 60.8433862660486 17.4013972333153 3.49646556826844 0.000519581623823274 -32.033276581467 40.1619152350483 -0.797603311345878 0.425532914617803 DUS2 other 1 1 1 3.49646556826844 -0.797603311345878 1.99072238569025e-09 223.417184376859 35.2926324447131 6.33041994605666 6.07135101731344e-10 103.416713185559 66.2301229445362 1.56147548257104 0.119135464882373 POP5 essential 1.40087134281023e-05 1 5.73621244115774e-06 6.33041994605666 1.56147548257104 1.75672406977386e-07 237.420430170221 41.9737754369745 5.65639920875639 2.79450194805875e-08 37.5778667018544 117.959840135757 0.318564917166782 0.750208308934899 ENGASE other 0.00111710083596919 1 0.000258044309883745 5.65639920875639 0.318564917166782 0.180982817766752 -176.698306998782 106.549078731599 -1.65837479875252 0.097957757031178 -315.767091886052 299.437259644747 -1.05453507108861 0.29221936098882 RBFOX3 other 1 1 1 -1.65837479875252 -1.05453507108861 0.00570293355027311 338.761359556389 127.194015155885 2.66334354758134 0.00802200314139842 784.989428332065 357.456186340495 2.19604376236567 0.0286123881527544 TBC1D16 other 1 1 1 2.66334354758134 2.19604376236567 4.39829067767475e-08 153.719020172911 25.9148783097874 5.93168983220175 6.10236212593046e-09 85.7780979827091 70.0499474365302 1.22452765664713 0.221412933284852 TEPSIN other 0.000289495492404552 1 5.69838575319386e-05 5.93168983220175 1.22452765664713 0.0650173697277705 101.158984820395 44.8113628204648 2.25744048949559 0.0244723041487036 70.3245554221869 69.7266698195772 1.00857470468842 0.313735484825411 MYO5B other 1 1 1 2.25744048949559 1.00857470468842 0.0254033577157816 239.455733818722 95.590958629833 2.50500400091176 0.0126071368505697 126.338299906642 148.739935378071 0.849390579507191 0.396128004337771 ACAA2 other 1 1 1 2.50500400091176 0.849390579507191 5.95155853795858e-11 563.368306855879 113.192321080946 4.97708944808194 9.30990272356395e-07 78.650444101626 131.067616987038 0.60007533446957 0.548767778480058 RRM1 essential 4.40296300638176e-07 1 0.00835936165548807 4.97708944808194 0.60007533446957 2.45442736279095e-23 91.8557163778199 27.9230756345747 3.28959880995642 0.00108430669493366 -145.572685242953 33.1338093987942 -4.39347868187624 1.40087002860206e-05 TRIM68 other 2.1532691253765e-19 0.117631056301715 1 3.28959880995642 -4.39347868187624 0.0121955561942723 -30.5413103961361 81.5646322682696 -0.374443058796421 0.708258018221341 -636.766486960247 213.998733611137 -2.97556194008761 0.00308828283847938 FN3K other 1 1 1 -0.374443058796421 -2.97556194008761 7.97414111577596e-06 87.0267039001861 22.4485058349177 3.87672589615385 0.000122091830262327 -83.4107640131298 53.5761849722284 -1.55686270040255 0.120225320039524 ZNF23 other 0.0447827765061978 1 1 3.87672589615385 -1.55686270040255 4.17602075041613e-51 419.082305509622 66.2023707676017 6.3303217188517 6.09890980589777e-10 -167.846335546113 81.5752891431085 -2.05756347674916 0.040227511162525 IRGQ other 3.99478144984807e-47 1 5.76164009363163e-06 6.3303217188517 -2.05756347674916 3.98628084955212e-63 195.616905027444 32.1052170064438 6.09299432513357 2.438054290459e-09 -143.084872057504 39.554561550459 -3.61740508423974 0.000332404664527211 ZNF226 other 3.87067870491511e-59 1 2.29006439502814e-05 6.09299432513357 -3.61740508423974 2.41412802269816e-43 135.191383137371 13.1132055214734 10.3095603066687 1.85418418206118e-22 45.906572551971 16.7811960749426 2.73559598177378 0.00647967169969518 ZNF180 other 2.27386718457939e-39 1 1.81672966158354e-18 10.3095603066687 2.73559598177378 0.196274912079579 154.766237565829 147.810819991019 1.0470562139851 0.295651103686684 -288.75073142189 314.071628172414 -0.91937859239987 0.358403615344328 MVD essential 1 1 1 1.0470562139851 -0.91937859239987 3.70868300627692e-08 269.110298420129 45.1162184633362 5.96482390559444 5.05257381680373e-09 243.017554125221 95.86391707064 2.53502633265181 0.0115908669124193 CDT1 essential 0.000245143946714905 1 4.72466177609317e-05 5.96482390559444 2.53502633265181 0.00385142835185059 144.683170878977 55.764356852832 2.59454567477235 0.00978998799915796 -105.020219097732 118.492858423752 -0.886299988832751 0.375943360119225 TRAPPC2L other 1 1 1 2.59454567477235 -0.886299988832751 0.000312246704163052 194.383593547832 120.164018325381 1.61765224113494 0.10645910186353 -698.782362920156 255.334748119406 -2.73673038263234 0.00645833548957475 ANKRD11 essential 1 1 1 1.61765224113494 -2.73673038263234 0.0786784260041615 40.8539635987234 18.7193923648888 2.18244069050829 0.0296087630540262 13.8413927945026 39.7765604134065 0.347978624864642 0.728023792411318 SPATA33 other 1 1 1 2.18244069050829 0.347978624864642 0.542475996308157 1.10698333413393 17.5526512354773 0.0630664461615066 0.949742495112158 -39.0291532587289 37.1701467452221 -1.05001342949354 0.294293589441655 PROCA1 other 1 1 1 0.0630664461615066 -1.05001342949354 0.00218517874523418 4348.73824721814 1321.0450606166 3.29189243945121 0.00107590475160975 534.213352885331 2807.06914189202 0.190310008725065 0.849154584005142 RPL13 essential 1 1 1 3.29189243945121 0.190310008725065 4.01807969957399e-05 3.85465294734028 42.7888224771311 0.0900855112196751 0.928260442544859 -232.888966930381 65.3331677416402 -3.56463607966079 0.000404444070780518 ZNF641 other 0.209462494738792 1 1 0.0900855112196751 -3.56463607966079 0.232607347884041 35.3388509281546 91.7840707517208 0.385021612560065 0.700408296480878 -153.057777126409 140.142769613201 -1.09215607447215 0.275364871172313 CACNB3 other 1 1 1 0.385021612560065 -1.09215607447215 0.95990145510775 11.1263354314774 43.3661337714015 0.256567382513928 0.797633777052306 17.3305693898736 94.8117881912127 0.182789183924281 0.855048399492486 DHRS13 other 1 1 1 0.256567382513928 0.182789183924281 0.0155258606065096 121.037174007011 49.8377271599994 2.42862547921643 0.0155595798296775 228.497950786867 105.538223663973 2.16507292669989 0.0309238975898731 TP53I13 other 1 1 1 2.42862547921643 2.16507292669989 2.90399009127583e-07 13.9203055047792 189.001438263154 0.0736518495980832 0.941321036120638 -1268.1564633563 288.581502238288 -4.39444820101171 1.39489677454842e-05 KMT2D other 0.00182254418128471 0.117143431126577 1 0.0736518495980832 -4.39444820101171 0.167319563668318 -96.1552519091291 83.7870011166073 -1.14761538935268 0.251756685689639 -311.469477930937 177.430468199108 -1.75544528001478 0.0798854032185999 CORO6 other 1 1 1 -1.14761538935268 -1.75544528001478 0.341970387056025 6.61121142822374 4.66931161152041 1.4158856761481 0.157519675620458 8.29068580956834 7.12945346688364 1.16287817124814 0.245512103188673 RHEBL1 other 1 1 1 1.4158856761481 1.16287817124814 0.00981968052972215 11025.3615425669 3662.66005021016 3.01020607739292 0.00276156161077032 12574.7226509897 5592.42273069976 2.24852863535519 0.0250389029109124 TUBA1A other 1 1 1 3.01020607739292 2.24852863535519 0.200093615485724 736.240344439497 637.70137917638 1.15452211408165 0.248915687265 -384.967135007774 973.690061161953 -0.395369276490687 0.692762866470098 TUBA1C essential 1 1 1 1.15452211408165 -0.395369276490687 0.000176465534438095 26.2014199324917 15.9765782140614 1.63998946341533 0.101735273271556 -7.85809490486149 20.1426377315344 -0.390122436276517 0.696638291996773 ZNF610 other 0.846714388458341 1 1 1.63998946341533 -0.390122436276517 1.44763777477566e-21 279.989746301126 51.2410285515205 5.46417107961852 7.8625243547845e-08 41.1666843628911 64.5924000424806 0.637330155495336 0.524246649208756 ZNF528 other 1.25481242317554e-17 1 0.000721072108577286 5.46417107961852 0.637330155495336 1.17960797265596e-34 20.1614592726178 5.46758748072122 3.68745069808345 0.000255168549645486 -38.6967012323414 8.12554635621627 -4.76235068214673 2.61080617866162e-06 ZNF701 other 1.08500341324895e-30 0.022673997074024 1 3.68745069808345 -4.76235068214673 5.25288626222479e-40 73.7455319019013 18.184159488358 4.05548202264258 5.9314170756965e-05 -120.568858620641 24.8302124814539 -4.85573205266349 1.67691799911256e-06 SERTAD3 other 4.90567048029173e-36 0.0146780632462322 0.498594919383048 4.05548202264258 -4.85573205266349 0.000284803879671776 48.6244318181844 74.024643315318 0.656868167686564 0.511611457525866 -319.287180397724 113.110908194263 -2.82277974330613 0.00497832036872419 NCKAP5L other 1 1 1 0.656868167686564 -2.82277974330613 1.64955831848338e-35 372.387782381172 67.5103598966357 5.51600943842294 5.96167480704884e-08 -248.281884921762 92.2053905293052 -2.69270466180448 0.00736121201462814 RAB4B other 1.52188250463276e-31 1 0.000547818298019718 5.51600943842294 -2.69270466180448 0.954515255839974 60.7884943181821 241.810018187198 0.251389478293337 0.80163117128493 106.901133404358 369.489801539716 0.289320931075461 0.772473004656143 GPD1 other 1 1 1 0.251389478293337 0.289320931075461 4.22962673763128e-62 122.193670777132 15.9026403598609 7.68386054214968 1.03403848326872e-13 -71.9239125757261 21.0099238659208 -3.42333047157732 0.000677181348401908 PROSER3 other 4.10400682352363e-58 1 9.99191386382568e-10 7.68386054214968 -3.42333047157732 1.10631574411427e-13 -0.158159718524145 4.21330207526007 -0.0375381863676086 0.970073113717069 -26.2343049566148 5.75625936521568 -4.55752656232714 6.73464121438774e-06 CYP2S1 other 8.70670490617927e-10 0.0574868974060138 1 -0.0375381863676086 -4.55752656232714 1.74522445560852e-16 -65.427428106355 129.911834536703 -0.50362946793635 0.614776723640225 -959.606212696695 176.786131162761 -5.42806274669373 9.48504295395262e-08 AXL other 1.43492354740132e-12 0.000861241900218898 1 -0.50362946793635 -5.42806274669373 3.07793932562581e-09 10.400141367562 17.3869204512613 0.598158908975021 0.550045204919666 -66.7788438753793 22.8649282306313 -2.92057964065324 0.00367551980995854 NFKBID other 2.14932503108451e-05 1 1 0.598158908975021 -2.92057964065324 0.000422870094343253 6.61451944844637 3.43497997939702 1.92563551698123 0.0547984221070384 0.403275708307792 4.26508653649607 0.0945527610886644 0.924713411115037 TMC4 other 1 1 1 1.92563551698123 0.0945527610886644 6.5133305352188e-12 -139.967004471398 131.449615697315 -1.06479584385926 0.287554960083617 -706.567439157334 163.106585021536 -4.33193692985505 1.83441747405453e-05 LAIR1 other 4.92798588294655e-08 0.153228891607775 1 -1.06479584385926 -4.33193692985505 8.30701569117079e-42 2453.4117728009 1329.2063825826 1.84577188685629 0.0655999891287698 -8965.55934139739 1649.31873480027 -5.43591675291503 9.0714298277812e-08 TTYH1 other 7.79031931517997e-38 0.0008242301141522 1 1.84577188685629 -5.43591675291503 1.19379812726834e-20 1982.01579802457 511.718981695131 3.87325049279762 0.000123787898938025 -563.86808726246 634.956102018454 -0.888042630773981 0.375005218551855 LENG8 essential 1.02642762982532e-16 1 1 3.87325049279762 -0.888042630773981 1.5810565530745e-06 10.9284218296047 3.39160177601623 3.22220076274438 0.00136703339957311 3.94478283047426 4.20840015776694 0.937359253538151 0.349090357469364 CDC42EP5 other 0.00943100233908942 1 1 3.22220076274438 0.937359253538151 0.160776495949576 -34.2250286162343 62.8129744493828 -0.544871961823973 0.586120808361231 -103.019599057677 76.9065891924031 -1.33954190583001 0.181093732670933 TMEM145 other 1 1 1 -0.544871961823973 -1.33954190583001 3.79328041351965e-50 54.5043055618753 11.2918769345271 4.82685968664941 1.92337548634177e-06 -48.1887656339157 13.8254834805611 -3.48550310748046 0.000541090169137294 ZNF526 other 3.62144481078721e-46 1 0.0171218885794144 4.82685968664941 -3.48550310748046 3.65638076672612e-48 455.050087820196 99.4670828615224 4.57488120420416 6.21969828867141e-06 -642.38874133775 131.944253992697 -4.86863748817213 1.57400084112007e-06 ZNF146 other 3.47721810915654e-44 0.0137913953698941 0.0544161403275862 4.57488120420416 -4.86863748817213 2.02330131518225e-24 48.0545556978935 9.30454120632397 5.16463462650179 3.67471063335594e-07 -0.704928411359434 11.4651579762049 -0.0614844045605354 0.951001673184827 ZNF283 other 1.7851587503853e-20 1 0.00332928783382048 5.16463462650179 -0.0614844045605354 0.324594946736641 167.468924278945 111.497678636647 1.50199471708016 0.1338190477886 190.104680809388 149.977933672328 1.26755100670162 0.205631792360896 PPP1R14A other 1 1 1 1.50199471708016 1.26755100670162 0.230203371136785 -101.002726769786 58.8316899205703 -1.71680818460512 0.0867211875536533 -115.087289978857 81.7841031147803 -1.40720856004666 0.160074765309867 SPINT2 other 1 1 1 -1.71680818460512 -1.40720856004666 1.26474316228494e-57 308.250602117452 39.0149105186892 7.90084093541089 2.26045262330077e-14 -186.579557563034 54.236066806552 -3.44013805847172 0.000637144204811921 YIF1B other 1.22098304886989e-53 1 2.18902232040447e-10 7.90084093541089 -3.44013805847172 1.31940016493346e-12 65.5303869220966 16.8265596119841 3.89446140109501 0.000113922277331484 9.92395105534196 20.8216085295924 0.476617886713108 0.633874118279557 DNAAF3 other 1.01343126668539e-08 1 0.943846067691342 3.89446140109501 0.476617886713108 1.80103526881219e-05 -2908.59950360229 775.412083827244 -3.7510371120942 0.000199825951671162 -8526.33117653136 2155.86872165984 -3.95493987684315 8.9292397935104e-05 ATCAY other 0.0975620805115563 0.713803429093221 1 -3.7510371120942 -3.95493987684315 0.00249523803843796 4350.83069707308 3801.73918519798 1.14443166275398 0.253069674602282 -28937.5522804795 10570.1985714463 -2.73765455633442 0.00643994494325336 EEF2 essential 1 1 1 1.14443166275398 -2.73765455633442 0.0507683683891436 -3.56008273856473 8.32446329609456 -0.427665137311008 0.669105117717351 50.0772602066417 22.9636695377443 2.18071681114954 0.0297357678826878 TMIGD2 other 1 1 1 -0.427665137311008 2.18071681114954 1.65001053736157e-13 385.796013939946 49.6310122499848 7.77328521926458 5.50725393520911e-14 101.859095268816 136.910948321088 0.743980642292629 0.45728711114353 CHAF1A essential 1.29344326023774e-09 1 5.32716673152777e-10 7.77328521926458 0.743980642292629 2.46861727030152e-06 654.845885770264 146.152449977605 4.48056728348109 9.51355026512067e-06 -454.751832092597 403.172726461777 -1.12793302285965 0.259965676750811 UBXN6 other 0.0145179381666433 1 0.0826727518038986 4.48056728348109 -1.12793302285965 0.00987604343210392 29.3920388024753 18.8557967903043 1.55877999372526 0.11977068697717 154.437364107711 52.0151595318523 2.96908373438975 0.00315087470035186 PLIN4 other 1 1 1 1.55877999372526 2.96908373438975 3.67304893904465e-34 319.659929591757 71.727214820724 4.45660591158766 1.06060500560126e-05 -170.405224733297 89.2056823949374 -1.91025078401248 0.0567581962173631 ZNF444 other 3.37296084072471e-30 1 0.0919968781858536 4.45660591158766 -1.91025078401248 0.964661548863065 -16.4077332565328 61.6109515612529 -0.26631195981806 0.790125438387002 2.03260435344069 43.8200017764581 0.0463853096996607 0.963024480991166 NXN other 1 1 1 -0.26631195981806 0.0463853096996607 4.34741009356064e-05 44.3281691580192 38.4270651643099 1.15356634623219 0.249312884135413 -121.354024099072 27.3307589169442 -4.44019957396193 1.14157150210304e-05 FAM57A other 0.225369739250183 0.0963714662075386 1 1.15356634623219 -4.44019957396193 8.21566944863785e-05 223.798295227566 64.16198391854 3.48802018827379 0.000536277796231481 -129.570022947073 45.6343909328564 -2.83930650324038 0.00473356461847505 GLOD4 other 0.411440725987783 1 1 3.48802018827379 -2.83930650324038 9.62086136902322e-07 125.688680414324 27.8514334330177 4.51282626858699 8.25321207491682e-06 -74.4091774973833 75.5606548604315 -0.984760886930173 0.325291466914566 MFSD3 other 0.00583890076486019 1 0.0719267432329001 4.51282626858699 -0.984760886930173 7.95273317852803e-09 76.5158360486052 13.4849143822709 5.67418033808232 2.55395341256788e-08 -10.9474500742296 36.5844351929587 -0.299237914060693 0.764902096187989 GPT other 5.45875605374164e-05 1 0.000235985295321272 5.67418033808232 -0.299237914060693 0.000320420829518632 400.551094491462 103.271588380204 3.87861851235206 0.000121373070258785 102.49540408348 280.17476605834 0.365826678560118 0.714673065892442 KIFC2 other 1 1 1 3.87861851235206 0.365826678560118 0.000685895609746371 -80.5827399137176 102.424670793825 -0.786751270852759 0.431855886980944 -270.873554407599 72.8060490488439 -3.72048144276963 0.000224899729813847 SLC43A2 other 1 1 1 -0.786751270852759 -3.72048144276963 0.000701028020389112 -12.2159843729748 8.75238842358131 -1.39573151713212 0.163507344555906 -21.7823862689552 6.22141927255488 -3.5011924634377 0.00051103816787699 RILP other 1 1 1 -1.39573151713212 -3.5011924634377 9.07399374756787e-06 19.4821708144938 8.82085199272628 2.20864955341716 0.0277173127707703 28.3074923911273 6.77492128475508 4.17827620445196 3.54851176019829e-05 SERPINF2 other 0.0507054770614092 0.291936062511513 1 2.20864955341716 4.17827620445196 0.1216165434612 96.9470009143196 50.734320365371 1.9108761133714 0.0566745288904893 24.0989842311589 38.9668738568983 0.618447975058504 0.536602287210522 WDR81 other 1 1 1 1.9108761133714 0.618447975058504 0.000147203184183872 193.631076246686 50.1220375843539 3.86319243148905 0.000128822905148497 56.236430099273 38.4745632036146 1.46165220386413 0.144553591747646 SRR other 0.714671459212698 1 1 3.86319243148905 1.46165220386413 0.0108418748511694 200.952649857479 68.0472659933056 2.95313333936514 0.00331494070954354 -45.3841602973046 52.2342858046512 -0.868857678403701 0.385400819057573 TSR1 essential 1 1 1 2.95313333936514 -0.868857678403701 0.0649056344809016 -10.6966832750543 13.3016370241381 -0.804162920371635 0.421739129334075 -20.8502973269941 9.69374847091535 -2.15090141750142 0.0320304093194146 TRPV3 other 1 1 1 -0.804162920371635 -2.15090141750142 4.38356417693117e-10 31.0005856702565 52.0408092322982 0.595697609771536 0.551684935976912 -255.124570681244 37.9254458684553 -6.72700253982894 5.43035983944709e-11 CYB5D2 other 3.16712511783277e-06 5.14906719976373e-07 1 0.595697609771536 -6.72700253982894 4.95920787715368e-43 617.374174518582 62.7202673518055 9.84329628341118 8.80189507213084e-21 237.996458366951 77.1570536444216 3.0845716253469 0.00216779690329256 C19orf48 other 4.66760645397705e-39 1 8.61001375955838e-17 9.84329628341118 3.0845716253469 0.63128569131974 -139.629466937555 229.101045557124 -0.609466738128614 0.542531126732916 -55.7066041682565 281.798779376702 -0.197682205336274 0.843385421264127 KLK6 other 1 1 1 -0.609466738128614 -0.197682205336274 4.91981279254376e-10 210.85697951107 73.4740092610982 2.86981725417713 0.00430730642945543 -134.964346007413 109.191937089842 -1.23602849811489 0.217114989346902 ZNF83 other 3.5488538161092e-06 1 1 2.86981725417713 -1.23602849811489 0.0466681768665445 -285.206757294814 307.592636981811 -0.927222316156024 0.354321760993677 -1156.02265903084 479.591873156515 -2.41043004215705 0.0163448032835586 SPRYD3 other 1 1 1 -0.927222316156024 -2.41043004215705 0.0151797173801211 238.42039701951 82.1885277183927 2.9008963128823 0.00390840769879986 239.164887932248 128.146597874418 1.86633817751936 0.0626621182581171 IGFBP6 other 1 1 1 2.9008963128823 1.86633817751936 0.0576159314489509 43.6468632952329 22.6282112220255 1.92886935988774 0.0543928969324731 21.4859750114025 16.4906159696741 1.30292131300096 0.193286187609865 ZNF232 other 1 1 1 1.92886935988774 1.30292131300096 7.30269484114298e-05 109.779885327712 25.0422614276337 4.38378481292316 1.46195603855827e-05 -13.3126918156952 18.4097444664726 -0.723132895187109 0.469984214876157 MIS12 essential 0.36827490083884 1 0.12619604524835 4.38378481292316 -0.723132895187109 0.489007565458523 -27.7464263060124 56.5378788648174 -0.490758175989488 0.623843270517533 -45.3786190023106 42.2621425400551 -1.07374156336967 0.28352970980032 TEKT1 other 1 1 1 -0.490758175989488 -1.07374156336967 0.0354573352139417 -27.3098013230033 10.5331477057719 -2.5927483489136 0.00983976447692192 1.41654206877805 7.87354245816605 0.179911656831021 0.857305127666447 TMEM88 other 1 1 1 -2.5927483489136 0.179911656831021 0.000315282115215696 15.1954761239875 26.1889782190623 0.580224092627145 0.562061876267209 298.278134599272 73.5994713813168 4.05272115412217 5.99020185143206e-05 TMC8 other 1 0.484487525743825 1 0.580224092627145 4.05272115412217 7.20798642152843e-11 216.515105670649 31.1382607809863 6.95334614844184 1.30292320131251e-11 170.969530887988 87.5085508890173 1.95374656706201 0.0513673281507882 TK1 other 5.3252603682252e-07 1 1.24689750365607e-07 6.95334614844184 1.95374656706201 8.2896767724099e-05 40.0598534244167 12.6085908541743 3.17718719623249 0.00159233605163789 -64.3034619065884 28.3226196973453 -2.27039244934732 0.0236687290662522 TMEM99 other 0.41498121922684 1 1 3.17718719623249 -2.27039244934732 0.369444841010346 -44.7917502339883 68.0291904063023 -0.658419569106598 0.510614499096331 -205.210857066453 149.001054407334 -1.37724432812035 0.169140125208583 GHDC other 1 1 1 -0.658419569106598 -1.37724432812035 7.13784735943071e-09 180.086198338531 30.1423865170859 5.97451692275431 4.78251258301646e-09 11.3960250168091 73.0152226896859 0.156077384920704 0.876043932972925 SDHAF2 other 4.9086976290805e-05 1 4.4745187726702e-05 5.97451692275431 0.156077384920704 3.19834987123149e-05 1378.589077257 348.288963171081 3.95817617849645 8.81025378320907e-05 -804.926790637655 843.675605841008 -0.954071428716104 0.340573721215989 DDB1 essential 0.168744939206173 1 0.73451085790614 3.95817617849645 -0.954071428716104 0.000265705909340651 81.0659308427837 22.5114745001382 3.60109378185271 0.000353152673109188 -37.6695290396235 54.53053038017 -0.690797041162138 0.490059015758904 VPS37C other 1 1 1 3.60109378185271 -0.690797041162138 0.279564252670318 50.2451141865705 36.2310413474612 1.38679740680684 0.166208917419485 105.267482209819 87.7640378861366 1.19943754577918 0.231006291874026 VWCE other 1 1 1 1.38679740680684 1.19943754577918 0.00023293228330185 126.332229580571 47.6406867384142 2.65177179905565 0.00829824716057416 -244.941942604859 114.512934942739 -2.13898930044313 0.0329901552339493 RAB3IL1 other 1 1 1 2.65177179905565 -2.13898930044313 0.00213209272788429 4171.15935430454 1671.51929252297 2.49542997975731 0.0129483167452671 -6264.8320364239 4017.79640690771 -1.55927065534055 0.119656209630107 BEST1 other 1 1 1 2.49542997975731 -1.55927065534055 0.00279010203407937 4190.29506990424 1862.95340842164 2.24927529103071 0.0249921366018439 -7847.54289919068 4477.94263821821 -1.75248848259326 0.08039113593049 FTH1 other 1 1 1 2.24927529103071 -1.75248848259326 0.941879457671172 18.0521322330383 55.6993614279775 0.324099446927785 0.746017455599675 26.9761328260116 99.1790943168899 0.271994143643008 0.785754686303384 TRANK1 other 1 1 1 0.324099446927785 0.271994143643008 2.37879394955338e-07 2612.89279819149 643.94986579422 4.05760283056952 5.87306925126675e-05 -1005.35354169656 1078.34697980471 -0.932309878475884 0.351691198503581 RPSA essential 0.00150078110277322 1 0.493807662646508 4.05760283056952 -0.932309878475884 0.0474217612997979 -34.6824458159915 26.3322960685472 -1.31710678498022 0.188493042831958 -109.189722979764 44.0955941528456 -2.47620482448399 0.0136564733849339 ENTPD3 other 1 1 1 -1.31710678498022 -2.47620482448399 2.66274378412956e-06 1556.7049180328 497.639998268864 3.12817483210372 0.00187633146821164 -1198.48579234973 810.081895332412 -1.47946250774799 0.139735591825303 CTNNB1 og 0.0156169922939199 1 1 3.12817483210372 -1.47946250774799 0.737685546462353 6.38099772226572 11.7669210958199 0.542282698278016 0.587899559310495 -2.42130614988246 18.9130105150749 -0.12802330691629 0.898189287046826 ULK4 other 1 1 1 0.542282698278016 -0.12802330691629 7.80838981685817e-11 92.3911565581366 22.1373149619919 4.17354845051287 3.62314699504434e-05 -146.393539717766 47.051091129368 -3.11137395975056 0.00198481843643931 KIAA1586 other 5.76337252382301e-07 1 0.30720663370981 4.17354845051287 -3.11137395975056 0.627985467670293 -43.3855919966437 78.5456283622199 -0.552361638722493 0.580982999934861 -118.495564588634 122.940249750633 -0.963846785971123 0.33565579480088 KCNJ4 other 1 1 1 -0.552361638722493 -0.963846785971123 0.00150917822425135 1056.38740172221 378.539450943754 2.790693015189 0.00548983971874029 -962.312761648673 881.652938577207 -1.09148704614044 0.275660037115659 SETD5 other 1 1 1 2.790693015189 -1.09148704614044 2.66302847119067e-08 48.5451450051964 15.6706972761438 3.09782928926199 0.00207484475162345 -40.2942671502876 22.9421988724674 -1.75633849982201 0.0797294490882434 THAP9 other 0.000177677259597841 1 1 3.09782928926199 -1.75633849982201 7.92860630805459e-21 319.835890131284 131.777507638207 2.42709014507535 0.0156256132155741 -708.87864112243 164.043966814988 -4.32127224722576 1.92430802324191e-05 MAPK1IP1L other 6.83049433438903e-17 0.160506532218608 1 2.42709014507535 -4.32127224722576 0.000447055518080051 -206.69918240765 758.590470791589 -0.272477957957948 0.785382943824395 -2366.90475742969 921.073427072292 -2.56972428892351 0.0105077057686056 DDIT4 other 1 1 1 -0.272477957957948 -2.56972428892351 0.00674824983001985 328.693083318596 304.831445942145 1.07827813598004 0.281505839554059 -938.925119715968 496.275504756841 -1.89194330712738 0.059160887520027 RBPJ other 1 1 1 1.07827813598004 -1.89194330712738 0.0041505091285415 -75.822590505775 130.217539543653 -0.582276325996446 0.560683626951317 -519.254779332792 187.088631211419 -2.77544806421727 0.0057513764808909 LMBRD1 other 1 1 1 -0.582276325996446 -2.77544806421727 5.85530610555786e-09 27.7700336104723 10.4833690243126 2.64896080125285 0.00836713844026427 -56.0252931993881 17.067265609731 -3.28261682219587 0.00111123708670003 ZCCHC4 other 4.04133227405604e-05 1 1 2.64896080125285 -3.28261682219587 0.00243484085969192 35.1518059420139 21.134907561123 1.66321077299976 0.0969988774410824 -52.5694588392512 35.7870573165104 -1.46895170436375 0.142577070438397 TTC39C other 1 1 1 1.66321077299976 -1.46895170436375 0.0250749881869412 6.69017051439122 21.3271308416911 0.313692946512666 0.753903938086158 -63.0422329129767 32.2637855575617 -1.95396268055722 0.051343133425083 GLYCTK other 1 1 1 0.313692946512666 -1.95396268055722 0.198815550816016 -21.6256948232021 222.211596371697 -0.0973202802027868 0.922516567721836 -842.703901840866 482.74172690966 -1.74566202767586 0.0815708781218332 GNG4 other 1 1 1 -0.0973202802027868 -1.74566202767586 0.0245120878042394 155.937340464327 57.7320897950309 2.70105137399251 0.00718077090873681 104.426887079129 105.940113665347 0.985716207639748 0.324817828827383 UBTD2 other 1 1 1 2.70105137399251 0.985716207639748 2.54389012648886e-07 402.897900135903 72.2298415362953 5.57799784087091 4.26613101086574e-08 138.879349144418 159.471228470029 0.870874015813575 0.384300004264407 NKIRAS2 other 0.00160188761265003 1 0.000392910666100735 5.57799784087091 0.870874015813575 0.000221366719654331 252.531059576521 93.209027059142 2.70929831094887 0.00700699282122162 -480.596079376909 205.789708705762 -2.3353747007051 0.0199745170740741 DNAJC7 other 1 1 1 2.70929831094887 -2.3353747007051 0.000871015322853326 622.902289580258 186.487844094021 3.34017636702482 0.000908904739558846 -285.45475574329 405.13395959327 -0.704593502923994 0.481437711236028 IRF2BP2 other 1 1 1 3.34017636702482 -0.704593502923994 0.00154550247496491 590.261363636369 177.757777250334 3.3205937471029 0.000973603014464304 857.530066287884 271.616893008629 3.15713082787028 0.00170363208154627 NT5DC2 other 1 1 1 3.3205937471029 3.15713082787028 1.5067728491429e-05 51.5784090909093 14.066348311379 3.66679453324676 0.000275859129368764 -5.1243134469693 21.4936183575999 -0.238410925592591 0.811674147888718 SMIM4 other 0.0823602039341507 1 1 3.66679453324676 -0.238410925592591 1.33451754885012e-09 81.533164871478 15.8289688692851 5.15088288724145 3.92710600326187e-07 -88.4554090200336 35.5171597976629 -2.4904978191937 0.0131259629157788 COA6 other 9.45639135115194e-06 1 0.00355638719655395 5.15088288724145 -2.4904978191937 1.62713130585874e-07 55.3211438409997 41.0990795561455 1.34604337708891 0.178989579895737 -151.501890182282 54.1200625613112 -2.79936650129792 0.00534812356877191 MGAT2 other 0.00103615721557085 1 1 1.34604337708891 -2.79936650129792 2.39183489916993e-13 322.00250608093 53.4064701082809 6.02927895118464 3.51333560676251e-09 -69.7251910272477 104.753680860809 -0.665610892660613 0.506011811678419 BMI1 other 1.86850142323155e-09 1 3.29410346490053e-05 6.02927895118464 -0.665610892660613 1.26196429270212e-05 152.472689503046 40.3337174200372 3.7802786168998 0.000178361635242361 -134.933978662725 93.0890386799883 -1.44951522301769 0.147909360921628 THAP11 essential 0.0694585146703248 1 1 3.7802786168998 -1.44951522301769 2.52552048072076e-17 105.462338285415 69.5466919694347 1.51642494127205 0.130136604457871 -808.890720643214 116.636599652057 -6.9351363384756 1.47149200628911e-11 PDHB other 2.09744475923859e-13 1.40247903119415e-07 1 1.51642494127205 -6.9351363384756 0.000233638915755364 -109.91066406379 90.8960062344029 -1.20919134533097 0.227244631721673 -610.549465638748 152.441486272163 -4.00513981180094 7.28596282997584e-05 PXK other 1 0.585572832645158 1 -1.20919134533097 -4.00513981180094 0.00752895662491374 9.92676107600275 42.7870694367171 0.232003762040413 0.816643944583721 -184.09926215134 71.7580972847487 -2.56555384155187 0.0106344645383651 KCTD6 other 1 1 1 0.232003762040413 -2.56555384155187 0.428010538688842 -37.5013234953511 29.2329969405953 -1.28284224746296 0.2002288797247 -42.3140819905366 49.0265929871769 -0.863084285738641 0.388565633239799 ACOX2 other 1 1 1 -1.28284224746296 -0.863084285738641 0.00901731008288543 -3317.36546669747 4447.92649699346 -0.745822906232784 0.456176304710915 -21997.4485656618 7459.60745824703 -2.94887481530175 0.00336083907393083 FAM107A other 1 1 1 -0.745822906232784 -2.94887481530175 1.09859420231437e-13 94.927954105707 50.406870263724 1.88323444024699 0.0603309589690767 -271.290050578771 66.5820575799286 -4.07452188231191 5.47445554920345e-05 IRF2 other 8.64703496641642e-10 0.443923600484908 1 1.88323444024699 -4.07452188231191 0.179791654618649 -938.9715946606 1118.967427891 -0.839141132490647 0.401848912968142 -3449.43954356258 1873.80293165818 -1.84087637247428 0.0663173972667294 MOBP other 1 1 1 -0.839141132490647 -1.84087637247428 0.70005976860857 288.551686522143 492.443777552208 0.585958640713155 0.558205811788759 686.78610592792 824.637581983346 0.832833866577028 0.405393355680971 CX3CR1 other 1 1 1 0.585958640713155 0.832833866577028 0.520243543320077 -10.3837047564332 14.57562205453 -0.712402168331886 0.476595953008758 -28.2552538477823 24.7963625843226 -1.1394918811861 0.255122254248443 XIRP1 other 1 1 1 -0.712402168331886 -1.1394918811861 0.00720620449037629 -34.6390290037839 20.1476551982753 -1.71925857688636 0.0862770454109141 -83.4443568726362 26.9819541952854 -3.09259871500399 0.00211154642587713 INSM2 other 1 1 1 -1.71925857688636 -3.09259871500399 1.12045254878995e-06 100.293313691792 50.7097548470584 1.97779133411862 0.048578612330814 -83.1961698993372 60.0287802359806 -1.38593803792585 0.16647102146084 DEGS2 other 0.00676081067939857 1 1 1.97779133411862 -1.38593803792585 0.213871106970281 -2.59298176650223 4.82723232386366 -0.537157027575346 0.591432541507691 -13.9156511747451 8.21219173586381 -1.69451123674737 0.0908806266070062 SCN11A other 1 1 1 -0.537157027575346 -1.69451123674737 0.0126776391792213 185.899815734186 265.198333908517 0.700984101198441 0.483686874637534 -907.238469693952 437.501897397106 -2.07367893737494 0.0386957026808211 ARF4 essential 1 1 1 0.700984101198441 -2.07367893737494 5.7799600190998e-22 -239.254478072863 873.692957066295 -0.273842745483764 0.784334563657709 -9529.60393621204 1279.13612012475 -7.45003114702338 5.01585047659813e-13 SEPT2 other 5.02914321261874e-18 4.8277560837257e-09 1 -0.273842745483764 -7.45003114702338 0.161527787818132 207.840703841137 109.890662082455 1.89134090106024 0.0592414173188242 133.836933868756 212.780891931736 0.628989439106651 0.529685368758959 FILIP1L other 1 1 1 1.89134090106024 0.628989439106651 0.616173582484632 107.753470290871 162.286311240988 0.663971406256574 0.507057964976425 198.033217583858 208.403629845567 0.950238811726102 0.342514948927515 MFSD2A other 1 1 1 0.663971406256574 0.950238811726102 1.60874996346051e-09 337.573687461399 62.6372608842498 5.38934306347171 1.15889637478627e-07 121.324300099117 92.1644387392278 1.31638950726315 0.188733351019054 DTYMK essential 1.13561659920677e-05 1 0.00105923128655465 5.38934306347171 1.31638950726315 0.736206826656104 258.841736694681 331.462282108217 0.780908569893251 0.435278121089823 271.106191194426 772.583720197415 0.350908495878157 0.725825713655229 TAP1 other 1 1 1 0.780908569893251 0.350908495878157 1.35853861908258e-10 161.049536751083 94.5807258673922 1.70277332166898 0.0893215752148426 -480.403461798122 139.166039383897 -3.4520164827922 0.000610585294418471 ING5 other 9.96216369373255e-07 1 1 1.70277332166898 -3.4520164827922 2.05246724164571e-10 277.909203211862 99.5905261019342 2.79051847690223 0.00549221650565017 -339.195954292773 145.806187550101 -2.32634814744209 0.0204554205470821 ATG4B other 1.49563287898723e-06 1 1 2.79051847690223 -2.32634814744209 0.618626295917734 8.7129678439642 16.3538058393512 0.532779215404325 0.594457854014052 17.9127569847128 19.4656372933038 0.92022453284254 0.357964289914468 BDKRB2 other 1 1 1 0.532779215404325 0.92022453284254 0.516812309685292 -11.9491160629194 10.5266600213365 -1.13512890496128 0.256942099474504 -5.57390056644761 24.2952230683917 -0.229423724604501 0.818646691872742 MLKL other 1 1 1 -1.13512890496128 -0.229423724604501 5.15757976713169e-05 209.104573343756 47.6439026409183 4.38890522717526 1.42937894170421e-05 71.0444627668489 109.960732099609 0.646089394007423 0.518559823467583 RFWD3 other 0.264635417851527 1 0.123455459194992 4.38890522717526 0.646089394007423 0.00192879854117302 24.4198080223764 7.6505564407349 3.19189959730964 0.00151541434529989 6.04532740795535 12.4105849575795 0.487110593788997 0.62642419938422 RHOH other 1 1 1 3.19189959730964 0.487110593788997 2.34030950306918e-15 42.0835311798891 38.4389053753516 1.09481606640325 0.274198897403657 -258.640797775409 52.7159227660792 -4.90631263201248 1.31094722535844e-06 CDC40 essential 1.89237426418174e-11 0.0115192932692247 1 1.09481606640325 -4.90631263201248 0.0171172733961926 -960.771963522507 1411.21114313165 -0.680813759300706 0.496349911085958 -6129.64123314303 2350.83475172477 -2.60743177658311 0.00943458820963316 RAB31 other 1 1 1 -0.680813759300706 -2.60743177658311 0.00595043160574771 -113.490653358963 130.490465179397 -0.869723724280826 0.3849310501724 808.608067336777 314.622363817943 2.57009087823357 0.0104990490009701 TNXB other 1 1 1 -0.869723724280826 2.57009087823357 0.00234604470967095 4.52419848887077 3.37726445419328 1.33960444917289 0.181070204422933 -5.80146348104277 4.46154336842141 -1.30032659148967 0.194174413462099 CCDC110 other 1 1 1 1.33960444917289 -1.30032659148967 2.31540956370862e-05 309.970014716704 71.591316955553 4.32971522103927 1.85314054296118e-05 528.888337012515 172.082570220086 3.07345675007115 0.00224839766820883 FEN1 essential 0.123851257562774 1 0.159129178424077 4.32971522103927 3.07345675007115 0.00622701925768051 42.5731066996991 41.3127509815554 1.03050766865432 0.303340453932533 -117.70834011158 68.2271528813776 -1.72524185958971 0.0851892583357752 MTCL1 other 1 1 1 1.03050766865432 -1.72524185958971 0.0168405342398882 107.978160640623 40.9764078859613 2.63512997384079 0.00870879684963925 165.130570512275 62.3545621908486 2.64825162282208 0.00838307794508538 GBX2 other 1 1 1 2.63512997384079 2.64825162282208 0.954743828346758 4.87133550488678 31.7313063168134 0.153518278013837 0.878060442260607 -17.3583061889248 73.6797099968542 -0.235591402160322 0.813860111827453 HEXIM2 other 1 1 1 0.153518278013837 -0.235591402160322 0.000106199546958973 -32.9909430767961 36.9551716101773 -0.892728720753944 0.372493792614736 -143.316398098517 47.4737331676862 -3.0188567137178 0.00268584179429477 SERINC2 other 0.524838161071244 1 1 -0.892728720753944 -3.0188567137178 1.71803915224778e-17 183.339115380701 52.2158387877936 3.51117821023224 0.000492402642814045 -235.269466037543 68.971510561233 -3.41111082131034 0.000707007528614587 TRAPPC11 essential 1.4297521825006e-13 1 1 3.51117821023224 -3.41111082131034 1.29268082448302e-09 46.5074578227374 21.8167140313821 2.13173522629664 0.0335845579688245 -80.5667809497943 28.8175342417104 -2.79575553807037 0.00540556799945978 ING2 other 9.16398246723086e-06 1 1 2.13173522629664 -2.79575553807037 6.27304810144348e-22 109.779469771549 31.5492647210646 3.47962054717084 0.000552420324602678 -182.982389083132 41.6731875887575 -4.39089015433262 1.41693823901054e-05 CDKN2AIP other 5.45692454344568e-18 0.118966134547325 1 3.47962054717084 -4.39089015433262 4.93156844568827e-07 43.827641424287 16.2627990855993 2.6949629761519 0.00731170470795818 -78.6290651294149 29.0619365761953 -2.70556867135345 0.00708606287403721 SNRNP48 essential 0.00305214771103647 1 1 2.6949629761519 -2.70556867135345 0.905026426595514 -7.40058250971738 16.6490865043852 -0.444503817537867 0.656897920741296 -7.65874995984532 38.4256041032122 -0.199313716429122 0.842109843033418 DYNLRB2 other 1 1 1 -0.444503817537867 -0.199313716429122 7.6147881254179e-10 189.250472347845 33.5453489704959 5.64163075227795 3.0274180192784e-08 -160.609956483049 75.8956834906931 -2.11619355800049 0.0348919030730865 TMUB2 other 5.44761942492396e-06 1 0.000279400408999203 5.64163075227795 -2.11619355800049 0.19179313063886 546.314948522536 300.210684674481 1.81977183495286 0.069476221441012 345.611445380398 657.536982193769 0.525615219736112 0.599421571484909 STAT3 other 1 1 1 1.81977183495286 0.525615219736112 0.263766221225243 3.24607449856737 17.9039221280698 0.181305217669494 0.856212263607931 -51.0265711556831 38.4286228492838 -1.32782721243507 0.184929931875695 GDNF other 1 1 1 0.181305217669494 -1.32782721243507 5.38850414118947e-24 631.829288089645 144.770179517887 4.36436074192737 1.59211402869502e-05 -321.540124964758 185.899015821742 -1.72964942037714 0.0843974284000156 NDUFS5 essential 4.74350019548909e-20 1 0.137208386992937 4.36436074192737 -1.72964942037714 6.88342992064935e-54 50.6639523516306 7.32248197825839 6.9189589680193 1.63108224136662e-11 -30.6855340921352 9.66899381210106 -3.17360158548568 0.00161217915701143 ZNF30 other 6.61635283972816e-50 1 1.5598039474189e-07 6.9189589680193 -3.17360158548568 2.77036088770558e-09 -144.275633979588 181.980317278796 -0.792809003396539 0.428321289099522 -1525.87627945774 285.476376055345 -5.34501768777503 1.46232141356084e-07 LDLRAD4 other 1.93952965748268e-05 0.00132135362929358 1 -0.792809003396539 -5.34501768777503 5.18646328400707e-09 9.56108313075195 76.224873358278 0.12543258794032 0.900238641531104 -323.045901146397 98.3457650332128 -3.28479727660159 0.00110249694114011 SLC16A4 other 3.58695800721929e-05 1 1 0.12543258794032 -3.28479727660159 2.70051181521263e-05 -2.73902132998684 33.8280339765653 -0.0809689777385326 0.93550360767045 290.933453100644 72.6038911108188 4.00713307027276 7.22172296516845e-05 IL7R other 0.143613218333008 0.580698743629195 1 -0.0809689777385326 4.00713307027276 0.0238863533541732 124.877592202999 51.9758621301106 2.4026074236228 0.0166947906472238 -47.0787857970872 119.960786354914 -0.392451460411411 0.694916011952214 TMEM208 other 1 1 1 2.4026074236228 -0.392451460411411 5.84117084492308e-24 -4572.00535051698 2071.00174919062 -2.20762988360768 0.0277877101741539 -20454.352801547 2672.01823284045 -7.6550199209544 1.24569189333916e-13 AHCYL1 essential 5.14139857770129e-20 1.20259095382963e-09 1 -2.20762988360768 -7.6550199209544 0.0454685067779377 15.1045496323523 30.6527345849467 0.49276352785079 0.622427745213163 -119.055995475114 63.8964394803633 -1.86326494000817 0.0630971323665792 DNAJC21 other 1 1 1 0.49276352785079 -1.86326494000817 0.100415949043022 444.753119450791 284.403473258359 1.56381043577047 0.118585931305721 -54.8347919837593 398.754260078136 -0.137515250553096 0.89068687539694 NPNT other 1 1 1 1.56381043577047 -0.137515250553096 0.510620412332602 -8.91874846073953 8.55546861301674 -1.04246171240347 0.297772706862376 2.14083385980506 19.7457710220107 0.108419866584023 0.913712291973297 CA7 other 1 1 1 -1.04246171240347 0.108419866584023 9.63245520571106e-36 11.5173514160361 58.1712419122094 0.197990468097928 0.843144377864654 -595.148954778473 77.3667508929222 -7.69256751653144 9.62275823438949e-14 GSTM4 other 8.89364589143302e-32 9.29173535112649e-10 1 0.197990468097928 -7.69256751653144 4.5858876706665e-06 43.9941614345506 83.7415281909502 0.525356563045203 0.599601791815427 -412.713280060883 117.411685339231 -3.51509544274452 0.000485501934060192 TET2 other 0.026387197657015 1 1 0.525356563045203 -3.51509544274452 0.000361218853120478 305.89055622249 114.010419262474 2.68300527444138 0.00757321311228635 -82.2290916366516 166.017066626971 -0.495305050904283 0.620633765967691 CXXC4 other 1 1 1 2.68300527444138 -0.495305050904283 0.000472817210472607 188.640133102515 48.5385269125579 3.88640004346136 0.000117523507126541 64.5584344117626 89.3808380412517 0.722284953089913 0.47050563082971 TCTN2 other 1 1 0.973094639007761 3.88640004346136 0.722284953089913 0.537664662774607 52.3037252914344 47.677132057001 1.09704009102104 0.273229389135427 63.7627516933143 105.173208052118 0.606264208102478 0.544654833685231 SHOX2 other 1 1 1 1.09704009102104 0.606264208102478 0.000203796965081217 -2.09317888443469 42.1132683686392 -0.0497035486800029 0.960381494361013 -205.872330547818 63.6834262847423 -3.23274582663499 0.00131957727574219 PPIP5K1 other 0.968850771996106 1 1 -0.0497035486800029 -3.23274582663499 1.75227802908161e-06 160.236791189168 156.384757867422 1.02463176958084 0.306103812693406 -681.411208377869 220.373767885044 -3.09207041708032 0.00211492930595805 TSPAN5 other 0.0104225497169774 1 1 1.02463176958084 -3.09207041708032 0.518125327715709 11.2202824071849 22.5567862794329 0.497423802672435 0.619140981056977 53.8969870163139 47.7670891342322 1.12832889743095 0.259801529379984 ABHD15 other 1 1 1 0.497423802672435 1.12832889743095 7.59790927636749e-10 206.735255570118 44.0632680381159 4.6917821753776 3.63530209977332e-06 -85.3575567358759 51.9192768124745 -1.64404363805328 0.100891332431795 ZBTB5 other 5.43630408724094e-06 1 0.0320888116346991 4.6917821753776 -1.64404363805328 0.000698659762502263 122.759132334111 53.9292427785621 2.27629994432093 0.0233121226213263 -260.58715573297 124.471311803061 -2.09355193544735 0.0368770298234568 CHTF8 essential 1 1 1 2.27629994432093 -2.09355193544735 3.8776362157746e-13 13.5735741487712 19.4433505654985 0.698108800900655 0.485481301920792 -162.827928882079 29.3979782401013 -5.53874581279769 5.2756836475354e-08 ADAL other 3.01369886690002e-09 0.000481511646510556 1 0.698108800900655 -5.53874581279769 1.45090694421382e-13 27.3959934200156 23.8370754576667 1.14930178698596 0.251061630051392 -191.727471437907 36.0412071598202 -5.31967396618309 1.6653089846889e-07 LCMT2 other 1.13881686051342e-09 0.00150194217329092 1 1.14930178698596 -5.31967396618309 0.145611942661363 65.4307448971901 45.9731385449946 1.42323859035972 0.155382150964585 -81.4693436913812 106.108236785296 -0.767794717541392 0.443024765658069 SNTB2 other 1 1 1 1.42323859035972 -0.767794717541392 0.416348600719968 -9.99837282729326 8.07421235872173 -1.23830937100547 0.21626922473854 -16.5607603530209 18.352790876101 -0.902356511596625 0.367366884620301 IL12A other 1 1 1 -1.23830937100547 -0.902356511596625 1.19100026330214e-45 156.106789640584 32.9546490456985 4.73701872607139 2.93893941490426e-06 -174.040931079797 42.6306933525586 -4.08252640041453 5.3000125059156e-05 ZNF507 other 1.12740084924181e-41 0.430891016730938 0.0260243085189772 4.73701872607139 -4.08252640041453 3.91796916497412e-14 111.893348877298 28.8534208668875 3.87799247075443 0.000121479199600023 -168.848623143565 46.2443372687989 -3.6512280879304 0.000292525134213964 STX18 other 3.10812493857397e-10 1 1 3.87799247075443 -3.6512280879304 0.779343928226007 -101.628961501063 160.031351180251 -0.635056573299776 0.525723120770623 -28.2110922029719 256.487569072063 -0.10999009544609 0.912467606639295 NSG1 other 1 1 1 -0.635056573299776 -0.10999009544609 2.35295965820325e-05 17.9460473391089 8.18057895298378 2.1937380523127 0.0287790039955375 -27.9010674504951 13.1112859685199 -2.12801913690888 0.0338932648176529 ZBTB49 other 0.12583628252071 1 1 2.1937380523127 -2.12801913690888 0.0141705444859861 34.1487499852388 75.4408063117312 0.452656216903776 0.651021978364995 -410.788654802251 164.770857316749 -2.49309047420058 0.0130344197974799 GFM1 essential 1 1 1 0.452656216903776 -2.49309047420058 0.00380424238054231 -197.363586073371 103.61415170679 -1.90479372578252 0.0574631343788583 -460.919709227954 140.351150663576 -3.28404652935682 0.00110555871657352 FSTL5 other 1 1 1 -1.90479372578252 -3.28404652935682 1.10521186988658e-06 179.73799763531 47.6808031467973 3.76960927193155 0.000185908787518882 -260.617227243734 113.796238725329 -2.29020950220322 0.0224836937275043 DDX19A essential 0.00667326927037519 1 1 3.76960927193155 -2.29020950220322 5.91427835998387e-08 274.594346913992 70.722240023177 3.88271563264968 0.000119220195073716 -177.498077830306 117.318375288599 -1.51296058604346 0.131010865416661 TNIP2 other 0.000385965805772547 1 0.986904774820221 3.88271563264968 -1.51296058604346 1.72503695716721e-07 45.870856393176 18.6706812360775 2.45683892372065 0.0144043103415774 -101.873738210024 34.4620756604058 -2.95611150105706 0.00328411706022553 LRRC28 other 0.00109746851214978 1 1 2.45683892372065 -2.95611150105706 0.000385477855051653 397.931116930198 504.973936619863 0.788023080149095 0.431114383138041 -1625.70966510707 588.761920346446 -2.76123439530608 0.00600315047490447 ENHO other 1 1 1 0.788023080149095 -2.76123439530608 0.466011306335257 -46.5603836413099 37.9058710317528 -1.22831588811948 0.219988016438995 -50.5698105243413 82.786262543693 -0.610847850483062 0.541617163245458 SLC35G2 other 1 1 1 -1.22831588811948 -0.610847850483062 0.0387366862098264 118.986811481768 164.278678053548 0.724298569306622 0.469272715228014 584.659049096752 255.154284480814 2.29139420600525 0.022418900473217 INPP5D other 1 1 1 0.724298569306622 2.29139420600525 2.24408039295824e-06 114.700622222225 73.6410970425534 1.55756264950732 0.12006084167442 -379.998222222219 119.748457222616 -3.17330369873401 0.00161354773166667 LETM1 essential 0.0132445624792395 1 1 1.55756264950732 -3.17330369873401 5.52688574375207e-06 350.044168916619 124.492975707617 2.81175838979645 0.00514892806552022 -316.715735668036 193.524798344831 -1.63656409089081 0.102441508982199 TMEM129 other 0.0315308831681056 1 1 2.81175838979645 -1.63656409089081 0.00286531469246921 -1.75187044468646 84.1643214275099 -0.0208148823037246 0.983402848135624 -323.295115736149 123.945630071628 -2.60836235653744 0.00941009543225493 STXBP6 other 1 1 1 -0.0208148823037246 -2.60836235653744 4.84073173318098e-09 491.958432304034 123.501135659245 3.98343245734525 7.95340345373327e-05 -566.808865795725 257.085206744261 -2.20475099665912 0.0279906799404254 MFF other 3.35123857888119e-05 1 0.664665926628489 3.98343245734525 -2.20475099665912 0.0705419211349975 1.16257624513537 179.159352230917 0.00648906256167378 0.994825481475502 846.485439380115 379.394504218385 2.23114839558368 0.0261790838871938 LGALS9 other 1 1 1 0.00648906256167378 2.23114839558368 0.00215242033047175 -50.4356533358045 94.6001373638362 -0.533145667028229 0.594204396074406 -431.208353067245 143.021160692621 -3.01499687863667 0.00271989168248169 JMJD7-PLA2G4B other 1 1 1 -0.533145667028229 -3.01499687863667 0.121522280383794 -486.411507889121 236.422967569532 -2.05737840485429 0.0402495236357534 -434.029977308021 367.646938862895 -1.18056192348682 0.238426396303509 CPLX1 other 1 1 1 -2.05737840485429 -1.18056192348682 0.00160920576914464 325.964094380484 125.895285786849 2.58916838977091 0.00994254201805272 -179.649589211656 217.227407771828 -0.82701161448447 0.408682855927921 PXDC1 other 1 1 1 2.58916838977091 -0.82701161448447 6.7703145548396e-06 -8.00317790952328 11.7661872958411 -0.68018447338095 0.496747018979264 -41.4932436041233 14.5521393574814 -2.85135007195979 0.00455920341312049 SIGLEC7 other 0.0382590475493986 1 1 -0.68018447338095 -2.85135007195979 1.0417439873675e-07 115.204756012912 132.977941474517 0.866344859421588 0.38677647469637 -965.255092494798 230.708307617473 -4.18387661225987 3.4654644257076e-05 FEM1B other 0.000670778953465932 0.285173067591479 1 0.866344859421588 -4.18387661225987 7.85207547225554e-06 26.7739646684049 15.0361020786243 1.78064531142466 0.0756650181829938 -61.1099570860644 23.7151473861844 -2.57683227057087 0.0102980557406708 COMMD8 other 0.0441129600031316 1 1 1.78064531142466 -2.57683227057087 0.000907092517513057 400.679273325638 158.354243596522 2.53027177690638 0.0117516666827369 -182.563931685178 246.247027150983 -0.741385322687533 0.458862669287202 ATP5I other 1 1 1 2.53027177690638 -0.741385322687533 4.80570266311536e-26 247.409754714031 71.4698878372963 3.46173419604727 0.000589906344825908 -242.843710025026 91.1407259260774 -2.66449172482993 0.00799775774477626 UQCRFS1 essential 4.27707537017267e-22 1 1 3.46173419604727 -2.66449172482993 0.182952240518059 23.3993126053321 12.6768085288814 1.84583624119761 0.0655999948595057 22.5908754329393 19.7129318615104 1.14599267078319 0.252432582567693 MFSD7 other 1 1 1 1.84583624119761 1.14599267078319 0.952881132109608 9.51543942992894 45.3398417408982 0.209869268717488 0.83386729272183 -8.54306413301625 94.3813392928776 -0.0905164537505238 0.92791819776836 COL4A3 other 1 1 1 0.209869268717488 -0.0905164537505238 0.00193229357934266 -71.6651484722566 194.623140235989 -0.368225219186986 0.712883607397977 -1078.24060393059 343.612696637479 -3.13795332501395 0.00181645921211479 MAP2K1 other 1 1 1 -0.368225219186986 -3.13795332501395 0.0112397218254071 -7.11162044358311 15.9469791943023 -0.44595408051476 0.655850778812349 19.1244133581351 19.722842899872 0.969658048549336 0.332752106962921 KLK7 other 1 1 1 -0.44595408051476 0.969658048549336 0.00574885081853034 1300.53263503188 433.316498210103 3.0013457609022 0.00284222717014322 2070.50007455176 852.392921602909 2.42904419086238 0.0155418676034777 HNRNPH1 essential 1 1 1 3.0013457609022 2.42904419086238 0.380238580041855 47.3793802763763 47.0836571188092 1.00628080263224 0.314836097105082 -39.6128378059707 105.773086985091 -0.374507721529903 0.708207861176913 IRS1 other 1 1 1 1.00628080263224 -0.374507721529903 1.40568102893361e-13 351.674770573193 73.3947503780669 4.79155210368133 2.29610935711292e-06 -193.991845945538 103.795851391651 -1.86897494788642 0.0623187862078603 UPF3A other 1.10402188012446e-09 1 0.0203756744350201 4.79155210368133 -1.86897494788642 1.19940338939349e-06 11.098614263529 39.1020320601567 0.283837275936305 0.77666951536656 403.316604945646 80.8860180161932 4.98623389848296 8.8955480381667e-07 ROR2 other 0.00721561079059126 0.00785832713691647 1 0.283837275936305 4.98623389848296 6.14866335440824e-05 61.2286945231353 17.4581138300868 3.50717695617356 0.000499659495543844 -26.4660309591263 33.801836268793 -0.78297613031043 0.434064260387545 HSPBAP1 other 0.31296696473938 1 1 3.50717695617356 -0.78297613031043 0.00123254063949514 79.8084941336191 52.7835748936511 1.51199486382683 0.131257964513453 -137.720692330069 81.3998221759626 -1.69190409325904 0.0913771266701841 CHST14 other 1 1 1 1.51199486382683 -1.69190409325904 0.406523572598045 -274.963260465244 216.827093443471 -1.26812224477348 0.20542948411847 -367.695080729943 308.869185580216 -1.19045569417753 0.234513607794268 PARM1 other 1 1 1 -1.26812224477348 -1.19045569417753 9.47176420027553e-06 84.0639122522965 30.3163810121229 2.77288744387667 0.00579379887244495 -84.5468398504108 51.7535279642285 -1.63364398865424 0.103053826758486 CSNK1G1 other 0.0528145571807364 1 1 2.77288744387667 -1.63364398865424 9.95000087432372e-06 -0.535938355299196 7.82662644202532 -0.0684762917035951 0.945437812649589 60.3333269534791 15.3490598250661 3.93075065450917 9.84282445734698e-05 ARMC4 other 0.0553419048629885 0.784276252761407 1 -0.0684762917035951 3.93075065450917 2.90473490184156e-07 607.980213200935 349.430976205808 1.73991504646356 0.0825763384654182 -457.867447105404 399.396102949287 -1.14639938578355 0.252255832027702 AFAP1L2 other 0.00182272115090558 1 1 1.73991504646356 -1.14639938578355 0.00212745506349015 45.9666626404157 16.2112564012515 2.83547810870891 0.00478763338382687 -16.2233447793902 31.089363535433 -0.521829427640104 0.602052876561154 ZNF354A other 1 1 1 2.83547810870891 -0.521829427640104 8.36007131303825e-05 64.0308450818998 25.6876950674427 2.49266603771913 0.0130472297662548 -139.086464020862 56.7764653401248 -2.44972037599825 0.0146872806069815 ZBTB43 other 0.418087166365043 1 1 2.49266603771913 -2.44972037599825 3.83618206772041e-13 157.836610233833 94.4939590307136 1.67033545692091 0.0955674034058206 -234.868063762952 115.406734473243 -2.03513308677324 0.0424390596577249 CPT1C other 2.98186432123907e-09 1 1 1.67033545692091 -2.03513308677324 8.93284837208281e-07 -128.549118784011 125.271489427903 -1.0261642084011 0.305383159756335 -1003.31164235021 204.236020763951 -4.91251072458861 1.27422223541692e-06 MN1 other 0.00543027852538914 0.0111991392270793 1 -1.0261642084011 -4.91251072458861 0.00999306355835012 183.797965299906 60.6837429733133 3.02878425578881 0.00260091332188253 214.866014402223 77.952548796002 2.75636932622328 0.00608930925082484 RAB3B other 1 1 1 3.02878425578881 2.75636932622328 0.249026508317083 0.994624954704302 32.5473854475631 0.0305592888960847 0.975634929349258 -91.0224233430539 62.4182033311765 -1.45826727597573 0.145483552658217 RGS14 other 1 1 1 0.0305592888960847 -1.45826727597573 0.087924831023643 184.776301485688 150.771442614003 1.22553912254287 0.221030727646408 -302.321657204976 289.144041286435 -1.04557457196736 0.296334169302728 LMAN2 other 1 1 1 1.22553912254287 -1.04557457196736 2.48506812367905e-05 214.450899867135 66.4283339548904 3.22830465705737 0.00133886299660261 -183.903870377719 127.393865858374 -1.44358497278172 0.149570594648154 RAB24 other 0.132677787123224 1 1 3.22830465705737 -1.44358497278172 0.0322714949571635 142.279683536659 67.3416880410674 2.11280245083687 0.0351828833290879 -49.9263282314976 129.145463422369 -0.386589872446498 0.699247595453011 PRELID1 essential 1 1 1 2.11280245083687 -0.386589872446498 0.430381387056082 89.4302920066872 69.5588079167374 1.28567890516089 0.199236013673363 101.840821944746 101.713230729323 1.00125442102772 0.317257907641464 CXCL10 other 1 1 1 1.28567890516089 1.00125442102772 0.242548130897671 -38.0467766411877 34.6166873242382 -1.099087740107 0.272334934703588 -108.229920750901 66.6842023149079 -1.62302190014657 0.105305845499107 SH3TC2 other 1 1 1 -1.099087740107 -1.62302190014657 0.691668675159385 15.8101956543118 20.7651626184295 0.761380777258151 0.446840336321745 6.46573591583952 30.3641169220212 0.21294002827233 0.831473038136222 CXCL11 other 1 1 1 0.761380777258151 0.21294002827233 0.0828748161854114 -22.8828593375323 16.7178502374252 -1.36876805405912 0.171774966322206 -70.311272856717 32.2045982349736 -2.18326812661057 0.0295473873280083 ADRB2 other 1 1 1 -1.36876805405912 -2.18326812661057 0.0138584450923916 -44.5110550526775 162.032129486107 -0.274705116780521 0.783672323658216 -870.942832764507 318.720076816049 -2.73262620122665 0.00653737287466743 GPRIN1 other 1 1 1 -0.274705116780521 -2.73262620122665 5.82620016663078e-05 31.5346728468353 22.4394299734437 1.40532414968453 0.160635408557405 -71.0223911913514 32.5746245982304 -2.1802980714998 0.0297682050558049 MRPL1 other 0.297544042509834 1 1 1.40532414968453 -2.1802980714998 0.11601190407618 76.0904583306881 47.1180405133013 1.61489012492376 0.107056230008033 -13.6041516172443 76.4339756663279 -0.177985660155022 0.858816712366582 PGM2 other 1 1 1 1.61489012492376 -0.177985660155022 0.00198507884465227 186.078426315075 168.521449337617 1.10418244707998 0.270120228849357 -884.454606604047 333.703722193072 -2.6504187630617 0.00833034774854838 STK32A other 1 1 1 1.10418244707998 -2.6504187630617 0.432120868136587 -135.236469412964 233.662095136641 -0.578769394898564 0.563042960169893 -660.384444966819 510.325718866278 -1.29404500018911 0.196333336788709 P2RY12 other 1 1 1 -0.578769394898564 -1.29404500018911 0.025352352409461 16.2961822128936 9.01663756250556 1.80734582042634 0.0713959201142035 -12.0227550462933 16.5240890771687 -0.727589580892848 0.467254491363761 KIAA1024 other 1 1 1 1.80734582042634 -0.727589580892848 9.15325047287399e-08 42.2106352491645 27.7518972880923 1.52099998104548 0.128986373716446 -178.916725422855 48.1523969611972 -3.71563487414825 0.000229118768506982 SNUPN essential 0.000592215305594947 1 1 1.52099998104548 -3.71563487414825 9.741483220809e-06 45.2803790270021 20.234787503395 2.23774917425769 0.0257394409973959 -68.2791522369749 32.2202002248026 -2.11914115246294 0.0346406566909248 CRADD other 0.0542405785734645 1 1 2.23774917425769 -2.11914115246294 0.000585798090219841 114.830759433212 100.464849857669 1.14299438655306 0.253669588399681 -417.153220976337 174.316850512029 -2.39307456365242 0.017130952829887 SIN3A essential 1 1 1 1.14299438655306 -2.39307456365242 0.252992701730182 35.048415767854 27.2587927143038 1.28576551922869 0.199220110982555 -27.8581397583417 59.5434396638661 -0.467862453287989 0.640121097148557 ARL13B other 1 1 1 1.28576551922869 -0.467862453287989 0.0799775957457677 -1.67569443499384 21.8425794380142 -0.0767168749345375 0.938883890182073 48.0472460770033 30.3613513930114 1.58251342158843 0.114255838037423 RNASE2 other 1 1 1 -0.0767168749345375 1.58251342158843 8.00834152276857e-25 -10.3473132694189 82.601889835067 -0.125267270398772 0.900369568101456 -649.072474346917 106.107954659977 -6.11709533396312 2.11798566627503e-09 PTAFR other 7.08177640858425e-21 1.97417443953496e-05 1 -0.125267270398772 -6.11709533396312 0.399897245616951 -4.12115905110629 105.274350273365 -0.0391468485951696 0.968791269310454 -206.887946262728 182.661828543531 -1.13262824484111 0.257994312496434 PTPN9 other 1 1 1 -0.0391468485951696 -1.13262824484111 0.119902614875327 61.4487390612013 62.6600407043812 0.980668674492336 0.327298753822996 173.61739047593 87.0979327109672 1.99335833896398 0.0468434730446721 RNASE6 other 1 1 1 0.980668674492336 1.99335833896398 0.858743163902862 -14.035927467492 96.4683158710458 -0.145497797289781 0.884384787275503 -67.0320986459297 137.408023458663 -0.487832493028291 0.625912590539779 CXCL8 other 1 1 1 -0.145497797289781 -0.487832493028291 0.446184133491645 0.205370715729779 12.7227095281463 0.0161420580478899 0.987128410573932 -10.8599048201142 16.3351847545799 -0.664816773319285 0.506517566643881 CD52 other 1 1 1 0.0161420580478899 -0.664816773319285 1.48371482238161e-24 761.649983339943 704.698942966457 1.08081612856371 0.2803736521343 -4545.23244194707 904.819907836355 -5.02335592152899 7.40743745918763e-07 CLIC4 other 1.30997181668072e-20 0.00656298958884024 1 1.08081612856371 -5.02335592152899 0.143929764289104 -15.9035377525703 34.6717813590831 -0.458688222213424 0.64668663426488 47.2345031312771 44.5526080381982 1.06019614139714 0.28964232800795 GPR183 other 1 1 1 -0.458688222213424 1.06019614139714 3.13565378953434e-09 140.149865763951 43.9616954410055 3.18799956093654 0.00153552637591761 14.2220834570791 53.6488745000268 0.265095653722837 0.791060774103617 CCDC8 other 2.18837277971602e-05 1 1 3.18799956093654 0.265095653722837 4.47658622340512e-26 47.2899490739564 10.4865708241772 4.50957227742432 8.36553451761786e-06 -68.4130214967328 13.1503260009526 -5.20238216845552 3.03676936958297e-07 METTL15 other 3.98550471469757e-22 0.00272367844757896 0.0728972677865221 4.50957227742432 -5.20238216845552 1.84579331799243e-47 27.8008293911119 8.4749149836432 3.28036675822332 0.0011195324136413 -63.0044449090893 10.8300484565286 -5.81755891139235 1.15381448278768e-08 DFFB other 1.75313449342921e-43 0.000106474000471647 1 3.28036675822332 -5.81755891139235 2.73265825339644e-15 55.4141702044673 22.4330188593849 2.47020566210084 0.0138852505917967 -252.780666356642 43.9817666968986 -5.74739682693254 1.70471403020673e-08 C15orf40 other 2.2071680712683e-11 0.00015691892648053 1 2.47020566210084 -5.74739682693254 2.11884199022021e-16 24.7458153943085 8.05022565100121 3.07392816886206 0.0022452324716849 -88.03725716686 15.7831252520702 -5.5779356598157 4.27807369980978e-08 FAM103A1 other 1.73935738977177e-12 0.000391272620584602 1 3.07392816886206 -5.5779356598157 5.69306637763513e-07 43.535739510751 17.1008143721673 2.54582843619473 0.0112450342250555 -71.0008115670375 28.0710439396938 -2.52932565385069 0.0117796481201668 HIC2 other 0.00351432987491416 1 1 2.54582843619473 -2.52932565385069 0.000160638913771335 -61.7996560572871 81.1718276244395 -0.76134365660975 0.446864366068881 -296.453441442408 103.849854230768 -2.85463512335464 0.00451460726915445 LUZP1 other 0.77636787025686 1 1 -0.76134365660975 -2.85463512335464 0.00024689470362542 235.985093279929 62.177265509684 3.79535978858985 0.000168335126391309 -131.761341905956 163.964523015675 -0.80359665299889 0.422068850837705 HEXDC other 1 1 1 3.79535978858985 -0.80359665299889 1.66832564681026e-09 204.71859675122 32.0634659378104 6.38479312087743 4.40061814580663e-10 2.8483351816019 84.5547857467396 0.0336862680976249 0.973142745085032 LRRC45 other 1.17667007869528e-05 1 4.16298476593307e-06 6.38479312087743 0.0336862680976249 0.0267564285263032 8.51579662430282 5.08935145616365 1.67325772205994 0.0949921997011685 -8.13800750474429 9.32685784736116 -0.872534741917051 0.383395879219873 CHRNA5 other 1 1 1 1.67325772205994 -0.872534741917051 0.0668860554095697 9.39579983501319 4.58155529376939 2.05078826567713 0.0408834144661548 18.0336754240009 10.5588020413091 1.70792816774553 0.0883598571515454 MT1B other 1 1 1 2.05078826567713 1.70792816774553 1.36850599442722e-09 232.811924710806 36.6545137358186 6.35152129936192 5.36633400555982e-10 -26.1655656327226 96.6618693560584 -0.270691698878082 0.786756257980589 CENPX other 9.68217991057262e-06 1 5.07225890205514e-06 6.35152129936192 -0.270691698878082 0.0605615927822839 58.0483569440399 25.3481663208966 2.29004166254763 0.0224945984468076 17.8376573470146 53.0685962339694 0.336124537162653 0.736938286404254 AGPAT2 other 1 1 1 2.29004166254763 0.336124537162653 3.55901181391426e-10 361.881406252738 54.4237278090661 6.64933147399093 8.82970077618741e-11 14.9668888760954 143.521185556171 0.104283481341768 0.916992339799934 ASPSCR1 other 2.57565684972975e-06 1 8.40322622869756e-07 6.64933147399093 0.104283481341768 0.0107646661880996 1215.39743862539 609.932904923043 1.99267399547617 0.0469201253570742 -2952.78104652883 1608.4582432755 -1.83578346461499 0.067070524918313 FASN other 1 1 1 1.99267399547617 -1.83578346461499 1.62858006948526e-06 572.339514683584 297.997590350514 1.92061792852211 0.0554317973029056 -2173.75404266215 608.854589514901 -3.57023512690291 0.000396324516534371 CNBP other 0.00971122295434063 1 1 1.92061792852211 -3.57023512690291 0.00630126749664509 316.4655835349 229.195832323184 1.38076500051126 0.168056979258954 1678.83103214438 528.21220459451 3.17832684959099 0.00158647674822841 MT1E other 1 1 1 1.38076500051126 3.17832684959099 1.86416653609227e-10 434.846254940884 63.3069868216136 6.86885092424622 2.24119067345166e-11 242.820040403233 166.947288772698 1.45447130162046 0.146535186922898 DUS1L other 1.36028232138653e-06 1 2.14078533128102e-07 6.86885092424622 1.45447130162046 2.45639010105422e-18 956.947180410189 104.366996615043 9.1690592950555 1.90080415545352e-18 -104.689681154923 275.226921971939 -0.38037587458685 0.703851660299231 GPS1 essential 2.0655784359765e-14 1 1.85480469489155e-14 9.1690592950555 -0.38037587458685 4.1276719675827e-11 406.325278554496 57.6280569308179 7.05082385550993 7.00897262306284e-12 77.5117141834373 151.971343841531 0.51004164485288 0.610280377970445 RFNG other 3.06768580630746e-07 1 6.72230564277957e-08 7.05082385550993 0.51004164485288 0.0146138947150112 321.284109314021 128.490237936599 2.50045540014139 0.0127695070436186 -333.133996540442 338.842486970971 -0.983152967381514 0.326077401369743 DCXR other 1 1 1 2.50045540014139 -0.983152967381514 7.63769655109213e-23 241.015691352566 84.361270438272 2.85694715241302 0.00448198790424534 -447.586547139913 108.421120464792 -4.12822285197891 4.38159339480323e-05 ZNF32 other 6.67992940358518e-19 0.358107628157268 1 2.85694715241302 -4.12822285197891 0.122676980799264 -55.3934470507583 88.3487944402485 -0.626985884773127 0.530996657914925 -279.38137582847 142.020291551476 -1.96719336917575 0.0497945338203763 LDB2 other 1 1 1 -0.626985884773127 -1.96719336917575 4.42642025878234e-08 324.335284236982 57.497129237997 5.64089526790922 3.04730908210311e-08 -103.77948697409 151.626073525582 -0.684443542993814 0.494058777598492 RAC3 other 0.000291258453027878 1 0.000281175209005654 5.64089526790922 -0.684443542993814 0.0426309800020829 -6.80894761980566 7.36504348319628 -0.92449523690398 0.355741081452291 -31.3338185457274 12.7791081725975 -2.45195659372516 0.014600279228857 NRG4 other 1 1 1 -0.92449523690398 -2.45195659372516 0.224502854125419 -7.73046521498868 8.0462828022594 -0.96074987729961 0.337211662970467 -24.5987410604882 14.2072089147367 -1.73142671499486 0.084084684258474 TMEM266 other 1 1 1 -0.96074987729961 -1.73142671499486 0.000669063681548959 -102.023483528585 106.210986058261 -0.960573734553418 0.337298932658143 -618.540426870716 170.733684613723 -3.6228376858974 0.00032569918227451 TAPT1 other 1 1 1 -0.960573734553418 -3.6228376858974 0.76669726541145 -324.745562835453 543.295760593286 -0.597732554512898 0.550329438988382 -672.451673372676 995.742563855492 -0.675326834246152 0.499826951547819 LINGO1 other 1 1 1 -0.597732554512898 -0.675326834246152 0.236095660283625 -179.112695466034 182.074500289466 -0.983733005891965 0.325792376237974 19.6488841504583 234.002181651537 0.0839688075204287 0.933119771678404 HNRNPF other 1 1 1 -0.983733005891965 0.0839688075204287 1.12543890380818e-05 71.8282142655136 32.8582833779804 2.18600020698733 0.0293442996726282 -202.316335765597 68.3355515434925 -2.9606307580152 0.00323687343817488 BTD other 0.0622142626025163 1 1 2.18600020698733 -2.9606307580152 9.85259596081229e-08 46.7934350863532 52.5430610104638 0.890573068764199 0.373649409118481 -191.161033926761 67.528351787599 -2.8308262954208 0.00485751599446615 CSGALNACT2 other 0.000635689491391609 1 1 0.890573068764199 -2.8308262954208 0.109315101978019 91.0196372412775 51.2890725759282 1.77463995096679 0.0766598850955177 38.1278431946166 62.7372623847609 0.607738395736534 0.543679594018594 GSX1 other 1 1 1 1.77463995096679 0.607738395736534 0.00552442825647093 -391.537996004952 175.280733062877 -2.2337765775118 0.0260041878759417 -902.529041277234 281.762993718969 -3.20314967329392 0.00145898789529433 PCDH7 other 1 1 1 -2.2337765775118 -3.20314967329392 0.235525932625009 -58.8439546368397 609.718443480389 -0.0965100453595387 0.92315984108483 -1455.85119192479 969.830964566796 -1.50113911095331 0.134043408489645 ROBO1 other 1 1 1 -0.0965100453595387 -1.50113911095331 1.02548214543922e-05 26.8229582250876 12.8307553142517 2.09052059431717 0.0371483036914034 -46.5368284932277 20.5638948809685 -2.2630357119894 0.0241234176492022 AVEN other 0.0569040042504223 1 1 2.09052059431717 -2.2630357119894 0.00126393946286162 1775.9265508357 933.542337794763 1.90235244716467 0.0577837284569915 -2020.24471163375 1530.4830886191 -1.32000459636345 0.187526083984626 CTNND2 other 1 1 1 1.90235244716467 -1.32000459636345 0.580424510039182 -15.677281538364 25.9710564091278 -0.603644352828639 0.546392603114402 -41.363287439407 39.6545472994029 -1.04309064801831 0.297481681712887 WNT10B other 1 1 1 -0.603644352828639 -1.04309064801831 0.082158176907614 279.655324018311 153.839274155468 1.81784089630906 0.06977303532979 625.384907251263 321.102159809194 1.94761974700787 0.0521004994916783 TM4SF1 other 1 1 1 1.81784089630906 1.94761974700787 6.44320260175931e-14 42.7096265025282 25.7570267895994 1.65817378113588 0.09799997450469 -92.2978382834458 32.926418998068 -2.80315446052185 0.00528578084790611 OTUD3 other 5.0888414148695e-10 1 1 1.65817378113588 -2.80315446052185 0.00252448682226122 -151.467762326174 63.8934340585305 -2.37063110721862 0.0181907663318384 -358.384299445319 103.64669521198 -3.45774941219637 0.000598080615445518 OTUD7A other 1 1 1 -2.37063110721862 -3.45774941219637 1.93269105038207e-11 557.842483949526 115.319548731782 4.83736270289259 1.82544789850951e-06 -686.240425060879 237.939029359072 -2.88410197734007 0.00411885486088496 BRD3 other 1.44739232763113e-07 1 0.0162629153278212 4.83736270289259 -2.88410197734007 0.000305184005723523 -44.1340075853349 235.819131636724 -0.187151938347915 0.85162836475345 -1296.91021298217 382.541242649674 -3.39024938592011 0.000761708161230737 KLF13 other 1 1 1 -0.187151938347915 -3.39024938592011 7.48904512439006e-11 3.0242544705689 3.57810352523388 0.845211562281789 0.398457369340522 -15.6058155967749 4.75255864488079 -3.28366607607982 0.00110740313518201 TAS1R3 other 5.52991091984962e-07 1 1 0.845211562281789 -3.28366607607982 8.90926638521067e-38 86.6976209844198 15.434866346221 5.61699849157725 3.47174073630073e-08 -61.4015207214048 20.5011137796851 -2.99503341044078 0.00290084760235384 PUSL1 other 8.27492661858367e-34 1 0.000320059778479564 5.61699849157725 -2.99503341044078 1.43744091166767e-13 238.051564677002 129.074402976252 1.84429723622895 0.0658164935928219 -521.568777229799 163.880808803189 -3.18261046573288 0.00156372340685459 SF3B5 essential 1.12853485975029e-09 1 1 1.84429723622895 -3.18261046573288 0.0123099615737606 18.0705266220543 10.6641947318905 1.69450456188837 0.0908802685446685 -15.3166317014532 16.7824632811438 -0.912656947008633 0.361925057749873 ZNF35 other 1 1 1 1.69450456188837 -0.912656947008633 1.93990731992057e-05 3.71462254220874 5.32359319083551 0.697766040538824 0.485695453938467 -18.5402649712996 7.03160544642334 -2.63670439312407 0.00867049987793754 TIGD4 other 0.104696798056113 1 1 0.697766040538824 -2.63670439312407 8.77618443069997e-09 -85.0996272447009 61.6044459663592 -1.38138775391588 0.167864038725875 -346.296536217832 78.7192633069934 -4.39913334639994 1.36637324612704e-05 IFFO2 other 6.01344157191562e-05 0.1148709988019 1 -1.38138775391588 -4.39913334639994 0.234347826797027 365.296067237559 381.822347463953 0.956717357336046 0.339237688311942 -412.717411988581 285.412732092106 -1.44603714404511 0.148881946958712 NLGN2 other 1 1 1 0.956717357336046 -1.44603714404511 7.85667039074703e-05 -88.8626164206876 283.481851212692 -0.313468449710438 0.754074009676053 -964.959568129252 220.983977461687 -4.36664947030629 1.57622022627181e-05 CHD3 other 0.394483420319408 0.132024206152527 1 -0.313468449710438 -4.36664947030629 0.0861180756389251 1.67902404109296 18.2749927052464 0.091875497198472 0.926839156866673 -34.5436893885172 24.1383091519413 -1.43107328566711 0.153125563129327 TMEM154 other 1 1 1 0.091875497198472 -1.43107328566711 0.105252892984447 14.2643282617981 74.5201657208934 0.191415680893994 0.848288839349002 -205.140487297267 124.790142693113 -1.64388374650515 0.100919408365014 MYRIP other 1 1 1 0.191415680893994 -1.64388374650515 6.44089834036665e-05 908.024979296268 469.500965900368 1.93402153615368 0.0537572817909449 -2695.52278373748 968.545289784513 -2.7830632311858 0.00561881506788406 ALCAM other 0.326939999757011 1 1 1.93402153615368 -2.7830632311858 2.09697107495528e-10 335.972947413671 50.848407022962 6.60734459708744 1.1379848804048e-10 -82.6291330391922 39.6381044622649 -2.08458840704288 0.0376854189398526 CNTROB other 1.52743373099742e-06 1 1.08199602428889e-06 6.60734459708744 -2.08458840704288 9.88078315983208e-07 393.331623441755 73.8673245487407 5.32483917408189 1.61813118254793e-07 -38.2821205732226 57.5821524849108 -0.66482614701238 0.506511576242767 TRAPPC1 essential 0.00599071882980619 1 0.0014754120122472 5.32483917408189 -0.66482614701238 0.00589135343669514 37.8269952715293 23.1383892179498 1.63481541066759 0.102806197140617 -51.3140389629001 18.0371803682162 -2.84490357779655 0.00465075967494784 KCNAB3 other 1 1 1 1.63481541066759 -2.84490357779655 0.442927816901223 3.89986713371184 10.0160974979354 0.389359941286088 0.697199134749674 -17.0846634341619 19.2085109637532 -0.889431953700157 0.374259209684869 FAM153A other 1 1 1 0.389359941286088 -0.889431953700157 0.323888584080019 34.5203665232226 23.8285809440967 1.44869585831441 0.148138042652354 14.0230375426616 46.8712419753215 0.299182120030976 0.764942997681307 SIMC1 other 1 1 1 1.44869585831441 0.299182120030976 1.07984529050119e-20 60.0760862220412 44.2142078793563 1.35875070714748 0.174924898191089 -354.513171739403 59.3449716839328 -5.97376933007089 4.80282990933942e-09 TMEM192 other 9.28990903418176e-17 4.45558530689418e-05 1 1.35875070714748 -5.97376933007089 0.000296458117576788 63.0630552919871 36.8960554272999 1.70920860134349 0.0881222752569444 -209.732068202077 78.3998833462728 -2.67515791159717 0.00774980705112815 ZNF778 other 1 1 1 1.70920860134349 -2.67515791159717 0.0343955102864161 -278.966817044375 147.38889287365 -1.89272618584306 0.0590640533440258 -649.373051845059 254.078892156119 -2.55579299143846 0.0109367463288608 NIPA1 other 1 1 1 -1.89272618584306 -2.55579299143846 0.0455453599496186 6.04918312718108 2.73479477899641 2.21193311236354 0.0274938714105865 2.04519075597712 3.13103455886108 0.653199674909069 0.513975043156005 FOXD4 other 1 1 1 2.21193311236354 0.653199674909069 3.46044895252779e-05 541.727107133668 166.285007611963 3.25782290847184 0.00121046976351651 -505.985279268215 339.364251438567 -1.49097990469927 0.13668987757886 UBE2E1 other 0.181777383476285 1 1 3.25782290847184 -1.49097990469927 0.00730889483811097 -94.7740715528299 114.27793209185 -0.829329598619757 0.407370695888901 -423.253914227362 155.224603182243 -2.72671925423084 0.00665411482459081 RNF150 other 1 1 1 -0.829329598619757 -2.72671925423084 0.261271563893362 -11.6838459191447 47.5537266687761 -0.245697797788293 0.806031527005861 -56.6665885784971 35.3136628869457 -1.60466470895164 0.109290017460317 CCDC144A other 1 1 1 -0.245697797788293 -1.60466470895164 0.0502062195892445 57.1297630374704 27.077209486547 2.10988370370495 0.0354349936809972 23.8464047845589 20.2402514895105 1.17816741540575 0.239369571832327 CHRNB1 other 1 1 1 2.10988370370495 1.17816741540575 1.55507553571714e-11 54.2860600559715 63.2301801092481 0.85854666177096 0.391061335412408 -382.108236895847 85.8860449864558 -4.44901423690083 1.09591812249099e-05 USP38 other 1.16755071221643e-07 0.0926598772566134 1 0.85854666177096 -4.44901423690083 0.220543299142789 7.53936366267101 18.0495476385471 0.417703746024622 0.67636935769277 -41.4685715156043 33.1228246211102 -1.25196362296877 0.211254324275381 ADRA1B other 1 1 1 0.417703746024622 -1.25196362296877 8.85859916724338e-09 30.7458334153125 8.22013814756335 3.74030616802058 0.000208451052375532 -32.7888658324775 6.28733633015038 -5.21506471273714 2.85035423986994e-07 ADPRM other 6.06459698989482e-05 0.00255819293028327 1 3.74030616802058 -5.21506471273714 0.984620495758912 1.63907123383638 13.6772704761805 0.119839059751789 0.904665839806125 4.31059140685673 25.0992346373553 0.171741946283942 0.863720089686331 FABP6 other 1 1 1 0.119839059751789 0.171741946283942 3.27513129278822e-08 72.0879799564399 26.1066463931428 2.76128840414273 0.00600047466309085 -153.629407374691 47.9084510726836 -3.20672874899699 0.00144137550620125 PWWP2A other 0.000217304961276498 1 1 2.76128840414273 -3.20672874899699 3.39575648986313e-11 4.33178231843014 4.59795687452198 0.942110253889776 0.346656708483648 -33.6425247825209 6.95153811329136 -4.8395799942744 1.80753558115221e-06 USP50 other 2.52949900929905e-07 0.0157960534436892 1 0.942110253889776 -4.8395799942744 3.43061661765269e-23 501.781941670933 154.574959795075 3.24620457502407 0.00125932110187458 -909.755307583982 187.618010289808 -4.84897641851498 1.7269062291502e-06 USP47 other 3.00659240371082e-19 0.0151104295050643 1 3.24620457502407 -4.84897641851498 0.00197536750813154 58.9419713482233 131.059988079497 0.449732769031466 0.653126129287428 -671.301001933546 238.186951233764 -2.81837858227049 0.0050458243515966 PDCD6IP other 1 1 1 0.449732769031466 -2.81837858227049 0.000755668189193193 26.8358672826542 10.0778856764719 2.66284696454792 0.00803697972546451 -24.1782724345517 19.9476039888817 -1.21208905330325 0.226139263864602 MRAP other 1 1 1 2.66284696454792 -1.21208905330325 0.095028366627564 66.1306688281083 69.6378450595139 0.949636921871888 0.342822851834824 -153.350250430599 126.563687569338 -1.21164493051442 0.226304579315698 GLB1 other 1 1 1 0.949636921871888 -1.21164493051442 0.010278855015502 22.1621121393578 16.1209530204993 1.37473957719352 0.169915068060572 -7.82408689115251 19.0242695600689 -0.411268714756594 0.681076660595649 GON7 other 1 1 1 1.37473957719352 -0.411268714756594 0.00266413590946718 55.7454726491898 177.769648178387 0.313582623470407 0.753987681543158 -910.968786950043 323.135047775167 -2.81915809882648 0.00503380812736534 FAXDC2 other 1 1 1 0.313582623470407 -2.81915809882648 5.96843789134884e-05 155.085476787267 299.342300292784 0.518087409081773 0.604660078570311 -1939.37640357871 544.041323193801 -3.56475936826559 0.000404449461583714 CRTAP other 0.304151594943137 1 1 0.518087409081773 -3.56475936826559 5.30801763992974e-07 189.600635449235 50.1695821842051 3.77919502604362 0.000179114736245266 -153.024058719586 37.5018319755767 -4.080442225309 5.34185881675313e-05 ELP5 essential 0.00328035490147658 0.434024454810457 1 3.77919502604362 -4.080442225309 0.520258541722259 -9.14373739848124 9.92715659855217 -0.921083223348649 0.357516339581853 -19.2180368953627 18.449875317802 -1.04163505521468 0.298158147514023 CMTM8 other 1 1 1 -0.921083223348649 -1.04163505521468 9.79622727390018e-05 1882.1508257442 497.886201000382 3.78028316905042 0.000178358477786236 744.67194508631 372.170622914873 2.00088856894178 0.0460210168019627 GABARAP other 0.486284721876405 1 1 3.78028316905042 2.00088856894178 0.000315270509490496 -1.03188158269286 2.33035808408816 -0.442799580776284 0.658129305296133 7.35450058190089 1.82037918534676 4.04009265822271 6.30973757017226e-05 LGALS9B other 1 0.509322016664305 1 -0.442799580776284 4.04009265822271 2.24218052376261e-12 266.726832423111 38.645861579116 6.90182134708178 1.8089143717146e-11 83.2211371403024 29.1639255931944 2.8535643075335 0.00452813572820021 STX8 other 1.71459544652127e-08 1 1.72932213935916e-07 6.90182134708178 2.8535643075335 1.38625881755335e-10 347.316873478658 73.2789236092877 4.73965577511072 2.90084736659796e-06 648.494561580073 94.5871327542596 6.85605475815492 2.42354909334382e-11 CDK1 essential 1.01585046150309e-06 2.30673402704465e-07 0.0256928051259581 4.73965577511072 6.85605475815492 1.85454316708393e-06 -99.2195619123149 1477.54842768564 -0.0671514787963515 0.946491823904997 -5708.12109780089 1097.23571062807 -5.20227426295989 3.03263359256903e-07 UBB other 0.0109992955239748 0.00272027233253442 1 -0.0671514787963515 -5.20227426295989 0.0293213101627121 -31.2350512987542 18.2857559936776 -1.70816297174445 0.08831462976656 -62.2836764346871 23.8203557518342 -2.61472486320407 0.00923789238192533 FRMPD2 other 1 1 1 -1.70816297174445 -2.61472486320407 0.00419287414355546 7025.14259512336 2658.37210630216 2.64264832544285 0.00852080700408334 3689.95244431658 3000.31648626673 1.22985440409587 0.219411810923617 FOS og 1 1 1 2.64264832544285 1.22985440409587 4.20616747873711e-12 1022.58577285479 629.78072914871 1.62371715348777 0.105155608362018 -1663.31486010213 710.788944827722 -2.34009669425188 0.0197269130707877 TMED10 other 3.19752851733595e-08 1 1 1.62371715348777 -2.34009669425188 7.58810106315771e-11 95.9957163255596 17.3586608103327 5.53013376863833 5.53678639881635e-08 -55.0708805330791 36.1038544065231 -1.52534629441474 0.127901116950093 SETMAR other 5.60229501492934e-07 1 0.000509052141507176 5.53013376863833 -1.52534629441474 3.22313430720406e-05 2.99849244547896 104.156909554348 0.0287882240199762 0.977046635077054 -438.023834250892 139.141221054354 -3.14805225174632 0.00175621260901604 SMAD1 other 0.169923640675798 1 1 0.0287882240199762 -3.14805225174632 0.21395632855917 -164.15754165371 93.5353002108293 -1.75503303334353 0.0799543741685943 -168.451529847507 106.099313200141 -1.58767785357618 0.113082444018431 EMX2 other 1 1 1 -1.75503303334353 -1.58767785357618 1.42084564468396e-05 -152.292951222533 826.091832055908 -0.184353537116471 0.853821831054148 -3708.06378496603 1095.13181909189 -3.38595201081899 0.00077357465651119 DCLK2 other 0.0778055075028937 1 1 -0.184353537116471 -3.38595201081899 0.991066150926394 -2.05754407737643 70.6196466340424 -0.0291355759402028 0.976769732899694 -14.1730665983191 114.188288878968 -0.124120141719101 0.901277090616625 KRT8 other 1 1 1 -0.0291355759402028 -0.124120141719101 0.0127388326519711 4.13998673515233 11.5376055516187 0.358825470036243 0.719898952039287 -25.3895036460945 8.56789028986737 -2.96333202073338 0.00320954568528724 ADORA2B other 1 1 1 0.358825470036243 -2.96333202073338 0.203140691871227 47.4915669942749 36.5962923281189 1.29771525947137 0.195068208538535 74.212740002557 42.4843432334645 1.74682563867671 0.0813685174535812 MGMT other 1 1 1 1.29771525947137 1.74682563867671 0.881968895863825 17.8000169633405 325.596680843046 0.0546689140603402 0.956427219258444 223.810045801002 512.473297891323 0.436725282511136 0.662526295219217 METTL7B other 1 1 1 0.0546689140603402 0.436725282511136 0.0102672776315098 105.338025291166 79.5947497764896 1.32342931646831 0.18638778556801 -368.836839058276 173.84351784884 -2.12166000563212 0.0344310607179794 HARS essential 1 1 1 1.32342931646831 -2.12166000563212 0.000161089411211991 8.5773995089249 16.7575712223884 0.511852188786483 0.609013609864834 -82.1285071868019 26.7621459448111 -3.06883115263505 0.00228305733716047 NFXL1 other 0.778061856153916 1 1 0.511852188786483 -3.06883115263505 0.674575979969689 -135.455464908698 476.992496201428 -0.2839781883099 0.776561904374689 -894.624545327144 1008.36232526198 -0.887205444823331 0.375457429951719 CD14 other 1 1 1 -0.2839781883099 -0.887205444823331 0.604883062136854 -16.3274806489702 18.2594575961963 -0.894193081199272 0.371709674839436 -10.8723560881038 20.9513328793588 -0.518933862141784 0.604068951097344 RIOX1 other 1 1 1 -0.894193081199272 -0.518933862141784 0.000724762144161063 81.6854744899879 30.8835413658872 2.64495167578854 0.00846530420728081 -32.549218877034 49.6451544892524 -0.655637377139808 0.512403272394296 PYM1 other 1 1 1 2.64495167578854 -0.655637377139808 1.13151244845386e-16 104.500704830112 37.2827872251066 2.80292093504588 0.00528902101165441 -241.181408688044 54.582709624569 -4.41864118412111 1.25349779496828e-05 NUDT9 other 9.33045164995054e-13 0.105632259181977 1 2.80292093504588 -4.41864118412111 1.60235847158447e-10 115.209336072941 153.918491603203 0.748508739092554 0.454556936044838 -1234.52655708231 245.116356576071 -5.03649195152419 6.95464855650387e-07 PA2G4 other 1.17148427857541e-06 0.00616668687505198 1 0.748508739092554 -5.03649195152419 0.286207472200049 -4.78120893561031 50.6045356724992 -0.0944818260274767 0.92476962521877 -90.6185282522994 71.1362483230593 -1.27387274966713 0.203384054843682 ELOVL6 other 1 1 1 -0.0944818260274767 -1.27387274966713 0.00597143824137583 1077.45865374488 400.975104932515 2.68709613262953 0.00748259694475558 4.78706032197608 843.206768009935 0.00567720813398366 0.99547285830655 PFKFB3 other 1 1 1 2.68709613262953 0.00567720813398366 0.744285113913497 -23.406769355493 47.9600436345163 -0.48804729065441 0.625762814527697 21.3340794134749 82.7633316289867 0.257772119531289 0.796704964217634 SERPINB9 other 1 1 1 -0.48804729065441 0.257772119531289 0.480299155940482 -0.496313599532793 5.84270757636806 -0.0849458222999603 0.932343364407271 -8.96497311239264 8.84174468974559 -1.01393711614292 0.311173806227626 SMAGP other 1 1 1 -0.0849458222999603 -1.01393711614292 0.462904713954384 74.3646450718663 63.4063243319417 1.17282693572578 0.241508528959161 42.5609979714272 102.549001654727 0.415030836816198 0.678324418374237 IRX1 other 1 1 1 1.17282693572578 0.415030836816198 2.32405360312521e-06 536.054268590452 281.040979802419 1.90738827116001 0.0571316859790484 -1369.53625527192 490.203032837779 -2.79381432494143 0.00544020614653813 CDH2 other 0.0136886757224075 1 1 1.90738827116001 -2.79381432494143 0.145941335040354 61.5561309181488 38.3364344695479 1.6056822124928 0.109071087349671 8.00294824499042 58.9597867412796 0.135735705424241 0.892093154080596 IRX2 other 1 1 1 1.6056822124928 0.135735705424241 1.21501599709467e-05 650.866720216285 251.215810171946 2.59086687167817 0.0098936230367639 -1009.15085854531 491.821878804939 -2.05186247711754 0.0407783804185884 DLGAP1 other 0.066983831919829 1 1 2.59086687167817 -2.05186247711754 0.532282672507038 279.223362877004 249.792420543345 1.1178215987084 0.264258742416791 303.084993137059 402.824057944655 0.752400426835233 0.452216298974552 STAT2 other 1 1 1 1.1178215987084 0.752400426835233 1.71762939497061e-10 174.996723208821 38.5484106437838 4.53966117633025 7.30293863320659e-06 -141.464685111059 68.7427809021786 -2.05788423532595 0.0401965540424077 NUDCD2 other 1.25507179890503e-06 1 0.0637546542678935 4.53966117633025 -2.05788423532595 5.87211197723667e-28 206.1570705451 54.5547774239545 3.77890040578881 0.000179372110362047 -131.536192989137 66.9524452495283 -1.96462119492288 0.0500913054096957 IRF2BP1 other 5.27609261154715e-24 1 1 3.77890040578881 -1.96462119492288 1.29190875356084e-21 178.87078699443 20.7506998504173 8.61998815865638 1.29410725180907e-16 -120.904168252877 56.1305523395234 -2.15398144528403 0.0317966732701301 COMMD5 other 1.12008488933725e-17 1 1.25903694528505e-12 8.61998815865638 -2.15398144528403 0.203603059394662 -28.1569298669704 81.5181185705735 -0.345407013320528 0.729954987896705 -250.039604809659 148.183113106295 -1.68736909063517 0.0922476124919863 SGCD other 1 1 1 -0.345407013320528 -1.68736909063517 2.20728132393121e-27 79.9573552729329 7.87325263056157 10.1555683558994 7.29783697868492e-22 -42.5996651402088 21.2971139309857 -2.00025530587172 0.0461010806712944 ZNF16 other 1.97882770690433e-23 1 7.14750153692401e-18 10.1555683558994 -2.00025530587172 1.3778575969429e-08 105.50150060024 30.1881123109319 3.49480283873317 0.000522853951642478 -180.639105642254 58.2564603918682 -3.10075662728504 0.00205517465313212 RNF34 other 9.35565308324227e-05 1 1 3.49480283873317 -3.10075662728504 0.000120745040059292 195.947061680429 60.2360797817896 3.2529849616752 0.00123055824720343 8.15533553112737 88.0511675916426 0.0926204132686758 0.926247571053355 TRABD other 0.592616656611003 1 1 3.2529849616752 0.0926204132686758 4.27624197716314e-05 -4.97982954545924 91.9708385180451 -0.0541457447349703 0.956843790819869 -514.22827296402 140.532998286143 -3.65912831317372 0.000283987887605536 ATF7 other 0.221979721034539 1 1 -0.0541457447349703 -3.65912831317372 6.95748294297235e-06 140.548026111279 122.58426749214 1.14654212148628 0.252198299917152 -504.033260801994 183.934956607103 -2.74027987990691 0.00639017947897827 SOCS6 other 0.039247161281307 1 1 1.14654212148628 -2.74027987990691 0.00018802044326462 13.3657810209873 3.19607118506724 4.18194096659524 3.49248138597378e-05 10.2237242856104 7.01478607985965 1.45745346603855 0.145707819353215 CAVIN4 other 0.898925739248151 1 0.296406895227595 4.18194096659524 1.45745346603855 7.46255631593786e-30 9.73639933232014 5.53329998753103 1.75960084475097 0.0791767884199074 -31.5899961341155 6.90442902796285 -4.57532346355889 6.20717586873559e-06 ZNF296 other 6.7498821877658e-26 0.0530589393259518 1 1.75960084475097 -4.57532346355889 0.0526936722712592 -19.7040853971513 11.6105456712194 -1.69708521503812 0.0903909549340345 36.4795168741177 26.2186733291577 1.391356321357 0.164823672472803 TTLL6 other 1 1 1 -1.69708521503812 1.391356321357 0.243218682086047 18.6244956132238 21.6785872479484 0.859119434315829 0.390744559520549 -56.2462271252107 53.9677455043309 -1.04221932192252 0.297884918296221 POLH other 1 1 1 0.859119434315829 -1.04221932192252 5.3176470077132e-11 41.5982530432569 30.3464388997941 1.37077873224654 0.171149175288218 -137.936513938006 36.7333822547241 -3.75507251092477 0.000196789315351642 SYT9 other 3.94250349151856e-07 1 1 1.37077873224654 -3.75507251092477 4.4980723102509e-18 745.568332291756 176.739228867796 4.21846545935454 2.99348664247059e-05 -1441.05023227488 334.536136856426 -4.30760708190201 2.04090639370621e-05 KIF5B other 3.76533633091103e-14 0.169925866339979 0.254895387606371 4.21846545935454 -4.30760708190201 0.0018278047654532 81.1879460745444 26.2434481293333 3.09364629504602 0.00210426703236324 39.415543219667 30.7015229494524 1.28383022837537 0.199883208205122 CDCA4 other 1 1 1 3.09364629504602 1.28383022837537 0.0348598855001909 42.3697652113218 16.8605515704611 2.5129524994634 0.0123314715232698 53.4539077530778 26.7817247447609 1.99590983263818 0.0465639014610905 HTRA3 other 1 1 1 2.5129524994634 1.99590983263818 0.16039185478147 6.12751725828205 3.53019263892412 1.73574586007564 0.0833120473771235 10.6983630162167 7.43882383661194 1.43817937501923 0.151097268757596 CEL other 1 1 1 1.73574586007564 1.43817937501923 0.205497640284286 -79.0003509555537 94.9813032011465 -0.831746336310535 0.406006395575403 -280.605908815362 158.362180408918 -1.77192501448761 0.0771037657783273 GPR27 other 1 1 1 -0.831746336310535 -1.77192501448761 0.115480774873377 122.76034827487 85.5188713206318 1.43547671267329 0.151871595772483 -118.912583557141 169.877940260845 -0.69998837621031 0.48430960065504 RIOX2 other 1 1 1 1.43547671267329 -0.69998837621031 2.96272075755113e-07 144.48957376695 29.431247795666 4.90939340289295 1.29256896000768e-06 -11.5864440962991 55.2306536774099 -0.209782852905797 0.833934922665367 TRIAP1 essential 0.00185732964290881 1 0.0115516887955886 4.90939340289295 -0.209782852905797 9.42530269093122e-08 206.459329038219 50.4558011829011 4.0918848615605 5.09418627346413e-05 -224.749911445365 108.305125415161 -2.07515489764536 0.038555370640377 LSM3 essential 0.000609345818968703 1 0.429287077264822 4.0918848615605 -2.07515489764536 1.47478497133753e-07 -129.788948416864 142.134578233455 -0.913141263934285 0.361671750036639 -1159.16073404804 225.770143702184 -5.13425165542307 4.27295593941418e-07 KIAA0232 other 0.000941060290210479 0.00381745883627263 1 -0.913141263934285 -5.13425165542307 0.00289359824342234 374.573962370698 135.3951351354 2.76652452834521 0.00590550627233084 -215.100618599039 290.630348694404 -0.740117539566439 0.459625201646076 TMEM43 other 1 1 1 2.76652452834521 -0.740117539566439 3.47922546554455e-07 817.415821680941 958.324736923109 0.852963291238225 0.394145849740084 -2119.55389815589 1189.11777985809 -1.78245917608669 0.075366945774662 RPS9 other 0.0021710366904998 1 1 0.852963291238225 -1.78245917608669 0.173043221614903 30.0916559847945 23.0073986035443 1.30791214179941 0.191589130114639 -13.0933632425748 36.8747229525568 -0.355076925172312 0.722702878646978 CYTL1 other 1 1 1 1.30791214179941 -0.355076925172312 1.21203588023129e-57 287.354728339164 50.8499460460617 5.6510331019598 2.88075029556626e-08 -212.851972856785 63.1384816107954 -3.37119245548015 0.000814951887274228 TSEN34 essential 1.17022064236331e-53 1 0.000265950867286678 5.6510331019598 -3.37119245548015 2.94741917089032e-06 1021.58853940418 200.194937917858 5.10296888637289 5.00096462381135e-07 719.395285978597 422.083842990593 1.70438953758917 0.08902076853433 TRH other 0.0172174617569588 1 0.00451687124822641 5.10296888637289 1.70438953758917 1.72267621348157e-13 83.4176472033182 80.8911958230051 1.03123271147878 0.303004713411106 -1206.63549419867 181.446985682958 -6.65007186345338 8.8103231055103e-11 GSTA4 other 1.34920001039877e-09 8.33544669012329e-07 1 1.03123271147878 -6.65007186345338 2.39154677054989e-33 443.498281840213 86.5033992593306 5.12694628925089 4.43625767879628e-07 -128.256273651611 107.421199727427 -1.19395681650411 0.233144048958672 NDUFA3 other 2.19233092456309e-29 1 0.00401037694163183 5.12694628925089 -1.19395681650411 5.73311602467496e-09 2.17416197725346 17.8044485381799 0.12211341298166 0.902865462112613 -62.1517044661814 22.1098273458915 -2.81104431499464 0.00516067724808001 OSCAR other 3.95871661503806e-05 1 1 0.12211341298166 -2.81104431499464 0.176044504187131 -721.965781080645 405.74503912246 -1.77935824586322 0.075875975749451 -1176.58353626925 924.613778062145 -1.2725135231439 0.203867359526883 PAQR8 other 1 1 1 -1.77935824586322 -1.2725135231439 8.17038666494677e-23 22.4651930894317 19.5689107186002 1.14800427128929 0.251594847491587 -204.346725383918 27.5111143731807 -7.42778800640394 5.84496698426348e-13 NUDT6 other 7.14500313849595e-19 5.62402723225832e-09 1 1.14800427128929 -7.42778800640394 4.68542857480223e-11 71.6883350179179 20.5761304854546 3.48405328536359 0.000543830714970776 -63.2143664430764 25.7990457127937 -2.45025987188854 0.0146673946491101 DNAJC24 other 3.47986780250562e-07 1 1 3.48405328536359 -2.45025987188854 1.53377675746536e-53 61.4632067413814 25.2420435251733 2.4349536787735 0.0152956305577374 -318.989240123678 37.4332259173032 -8.52155357458059 2.62295106997208e-16 ZNF160 other 1.47288582019399e-49 2.55711499811578e-12 1 2.4349536787735 -8.52155357458059 1.14559077674595e-19 63.8814156272282 15.5178695738487 4.11663568399128 4.60081891131091e-05 -43.5839533405235 22.9084228828307 -1.90252963128197 0.0577620347856421 ZNF415 other 9.75355987321503e-16 1 0.388355124303754 4.11663568399128 -1.90252963128197 0.079652068902728 33.5750459756069 14.9379978019902 2.2476269189927 0.0250968622800931 27.3627467566443 18.0494801891084 1.51598530649963 0.130244408138656 CAVIN3 other 1 1 1 2.2476269189927 1.51598530649963 2.95556274800554e-25 -556.124585625717 215.951275034587 -2.57523177641182 0.0103443490470748 -2259.76112310884 278.621562981813 -8.11050336135092 5.11334047989871e-15 S1PR1 other 2.61951526355731e-21 4.9624969357417e-11 1 -2.57523177641182 -8.11050336135092 1.06040959410215e-06 148.606346130055 71.3553878477806 2.08262263877075 0.0378679687229001 -265.862747927922 108.829053531599 -2.44293908014856 0.0149640990757242 PYGO1 other 0.006415478044318 1 1 2.08262263877075 -2.44293908014856 8.72091540240019e-17 146.911663957904 16.9794238291356 8.65233505190047 9.67778317631606e-17 0.112332281410247 57.9393440754746 0.00193879104437077 0.998453952228894 TSNARE1 other 7.20260403084232e-13 1 9.41938636550843e-13 8.65233505190047 0.00193879104437077 1.13510153569427e-06 -137.598362731222 130.635007519626 -1.05330389873136 0.292786444513183 -547.837695728452 163.504009196008 -3.35060711001714 0.000876676441777948 FPR1 other 0.00684693246330786 1 1 -1.05330389873136 -3.35060711001714 0.000105665298899466 25.1063614005729 7.26605653886879 3.4552939777264 0.000603406843476199 -9.56656778479254 14.0687704450118 -0.679986060060026 0.49687334328167 FAM86JP other 0.522514903057858 1 1 3.4552939777264 -0.679986060060026 0.000166052197203593 68.303401153607 59.094660605926 1.1558303314252 0.248383538823568 -438.192123644277 130.616287489771 -3.35480461178008 0.000863651712184678 KYAT1 other 0.800703694915725 1 1 1.1558303314252 -3.35480461178008 2.40623043753509e-08 134.071391921373 32.351647675209 4.14419052987251 4.09465930678403e-05 -190.645864533058 75.9369307354899 -2.51058164567031 0.0124125483071247 JAGN1 other 0.000160928691662347 1 0.346449123946997 4.14419052987251 -2.51058164567031 2.39356111089882e-07 514.275414130706 148.850178190674 3.45498688938033 0.000603949758064016 -978.48166811976 349.386398637501 -2.80057172212638 0.00532697817550176 TADA3 essential 0.00150961899264388 1 1 3.45498688938033 -2.80057172212638 2.89217262784703e-07 511.364640208618 91.9914284855728 5.55882921514602 4.72757316504567e-08 509.344429956808 203.324904678559 2.50507644777722 0.0126045921086457 C9orf16 other 0.00181599519302515 1 0.000435125834110804 5.55882921514602 2.50507644777722 4.86313986967701e-35 41.9704923525807 45.6893385117803 0.918605821832139 0.358807363032684 -383.545064257844 55.0984335735072 -6.96108835373974 1.24004277811707e-11 MORN4 other 4.47797919199859e-31 1.18275280176806e-07 1 0.918605821832139 -6.96108835373974 3.05085682541167e-09 193.275459084822 45.7777040308359 4.2220435291956 2.95609637156919e-05 -222.431177215139 89.1755009362835 -2.4943081326122 0.0129947571622489 ZNF672 other 2.1313285782326e-05 1 0.251829849893979 4.2220435291956 -2.4943081326122 0.00754976789818884 163.343043900717 93.1895700524463 1.75280392224998 0.08034996363647 -305.453687836762 186.186570884412 -1.64057851426027 0.101617882421538 ZNF692 other 1 1 1 1.75280392224998 -1.64057851426027 0.0332512036197794 22.6142531171054 10.3904234017046 2.17645154993351 0.030055077589726 49.3435335343493 22.9655293161666 2.14859117136107 0.0322144028770815 NAIF1 other 1 1 1 2.17645154993351 2.14859117136107 0.0707649216806766 178.133103849328 89.934387907315 1.98070068629265 0.0482601652760905 -25.3078524799272 178.01883656878 -0.142163902246093 0.887016974112781 GRIK1 other 1 1 1 1.98070068629265 -0.142163902246093 2.87195005513862e-41 139.444813006377 212.632006069761 0.655803496302562 0.512295679987758 -1993.51502948653 253.981591685224 -7.84905321783012 3.26307040636854e-14 TRIM8 other 2.68986842164284e-37 3.15930476744602e-10 1 0.655803496302562 -7.84905321783012 0.482520582765512 -409.719731764552 339.855029626867 -1.20557207058077 0.228633410093768 -118.029659367669 918.676409023146 -0.128477947412596 0.897829719475632 NPTX1 other 1 1 1 -1.20557207058077 -0.128477947412596 2.91880111224952e-15 149.742320741186 68.2907605354837 2.19271713430955 0.028855460378877 -548.564059859939 107.078316834847 -5.12301720903984 4.52436460405801e-07 FAM98B essential 2.35693189814148e-11 0.00403844784558218 1 2.19271713430955 -5.12301720903984 3.78459543629396e-06 592.317088663919 142.980956974661 4.1426292087896 4.1215803412744e-05 1399.87691755326 401.822582114722 3.48381843097506 0.000544059923980084 GAA other 0.0219203767670146 1 0.348681246186692 4.1426292087896 3.48381843097506 4.25562097294896e-06 247.456643886691 50.2848608078611 4.92109632822144 1.22049852831725e-06 254.556928968824 141.316669286771 1.80132273321739 0.0723396502448138 CANT1 other 0.0245591886348885 1 0.0109136978402128 4.92109632822144 1.80132273321739 3.18829180004855e-24 109.872391815763 27.7319660161963 3.96194022997122 8.677226493839e-05 -84.430701356361 33.442985544914 -2.524616148369 0.0119346821697908 ZDHHC16 other 2.80952273420278e-20 1 0.723680689586173 3.96194022997122 -2.524616148369 0.00853224669946014 -69.2815148815301 342.1193498802 -0.202506858807578 0.839614742207297 -1522.04253756503 572.461226801034 -2.65876965339704 0.00813059202784774 CHST11 other 1 1 1 -0.202506858807578 -2.65876965339704 1.79244208345036e-20 94.3946220270707 20.0490569472445 4.70818264796461 3.35901065701253e-06 -26.2483836063974 24.1778863166161 -1.0856359924382 0.278237211578532 EXOSC1 essential 1.53755681918372e-16 1 0.0296802181653628 4.70818264796461 -1.0856359924382 2.49335114630019e-26 -264.457595409467 186.811841165307 -1.41563614897116 0.157592716515156 -1723.18810200279 225.283187642066 -7.64898668222249 1.29833706692275e-13 PGAM1 essential 2.22132653623884e-22 1.25302510328714e-09 1 -1.41563614897116 -7.64898668222249 0.0982039128659954 15.5520645128362 7.25317320768773 2.14417387638729 0.0325687379071175 3.2934483403937 16.4164902498225 0.200618298447155 0.841090169443532 KRT19 other 1 1 1 2.14417387638729 0.200618298447155 0.00347606509492373 -5.32775930274714 7.61029405765094 -0.70007272549356 0.484253553757249 -23.1145521950264 9.77235906001319 -2.36529911079579 0.018450358691445 LURAP1 other 1 1 1 -0.70007272549356 -2.36529911079579 0.218106292323412 -623.195792685642 842.184749777657 -0.739975157291995 0.459713322418776 -2160.89873577992 1273.58790193695 -1.69670168230516 0.0904667998188268 TPPP other 1 1 1 -0.739975157291995 -1.69670168230516 4.35014973760594e-05 109.83684534035 151.943190973257 0.722880996751494 0.470138816832027 -348.337386457366 195.109861414888 -1.78533972568742 0.0748980600069975 KCND3 other 0.225468260900116 1 1 0.722880996751494 -1.78533972568742 0.0125705081346397 -4.34400535924211 49.9935989701355 -0.0868912310521407 0.930797678323253 -118.939418531199 63.6666896161644 -1.86815773284688 0.062407538085615 PDE7B other 1 1 1 -0.0868912310521407 -1.86815773284688 2.17933842306727e-10 42.6657579188135 21.5471737675292 1.98010924212758 0.0483209705571594 -129.146616454496 32.856255211447 -3.93065538429048 9.85325139756788e-05 MRPL36 other 1.58634043815066e-06 0.784910006330257 1 1.98010924212758 -3.93065538429048 1.13531725350641e-32 83.0804979253107 26.1146847520888 3.18137089204822 0.00157076634438897 -97.2406177962196 32.3109077001615 -3.00952912553842 0.00276865402054606 ZNF581 other 1.03824762833161e-28 1 1 3.18137089204822 -3.00952912553842 0.00140248814967199 -202.352247707702 81.046968195687 -2.49672815914748 0.0129025416767185 -557.389506671749 159.291505101675 -3.49917910761136 0.000514691578703888 KSR2 other 1 1 1 -2.49672815914748 -3.49917910761136 9.81115804650171e-30 104.540947805197 21.0384326456401 4.96904639076627 9.69061699423609e-07 -20.7101623352991 26.0302148703889 -0.795620106803584 0.426686806252842 ZNF524 other 8.87223022145149e-26 1 0.00869635969062747 4.96904639076627 -0.795620106803584 3.52586351355184e-06 107.840724461543 26.87925882406 4.01204233968732 7.07837234890861e-05 -70.5892342041856 55.1066099439967 -1.28095766144794 0.200886359185018 ZBTB26 other 0.020471163559682 1 0.592813684221096 4.01204233968732 -1.28095766144794 1.80530930955804e-06 711.464128529815 219.047526014811 3.24798979232347 0.00125163300774005 -319.192597476511 340.838875675853 -0.93649117003916 0.349536415701027 DSEL other 0.0107343691546321 1 1 3.24798979232347 -0.93649117003916 7.8960570798277e-13 122.029522822346 20.9681475501361 5.81975696854319 1.13981983332545e-08 -136.864565209343 52.199141841685 -2.62196964127188 0.00904682993140565 POLR1C essential 6.09575606562699e-09 1 0.000105957651705934 5.81975696854319 -2.62196964127188 0.266787981759743 5.99498389664259 8.12069164877356 0.738235627694101 0.460766631719604 -21.9945890250365 20.2160507604863 -1.08797654327355 0.277203765812132 DLK2 other 1 1 1 0.738235627694101 -1.08797654327355 2.23261948978281e-06 36.5741679931899 51.5226240245375 0.709866174047571 0.478164867021026 -580.998210738037 128.26296424527 -4.52974258124137 7.62497809717481e-06 ZNF318 other 0.0131791528481879 0.064949563431735 1 0.709866174047571 -4.52974258124137 0.00590833136302942 89.5764139590833 106.511888185217 0.840999211311658 0.400807262398434 -650.892298435621 233.287851166948 -2.79008227466514 0.00549949002940286 WIPF2 other 1 1 1 0.840999211311658 -2.79008227466514 0.908219977065103 -16.5010450720711 467.176962927908 -0.0353207593299447 0.971840475472011 299.909976418899 848.747500955376 0.353355946357793 0.723995993064831 HOPX other 1 1 1 -0.0353207593299447 0.353355946357793 5.07512936583251e-09 -8.04521525482842 39.2347192509173 -0.205053468163668 0.837625608990938 -180.635578427208 50.6236509266625 -3.56820527798146 0.000399130093596294 LRRC8C other 3.5119895211561e-05 1 1 -0.205053468163668 -3.56820527798146 1.04353092095936e-40 261.995333872032 75.2463651408245 3.48183375212483 0.000547997709954875 -483.570411482558 97.088644830821 -4.98071028105491 9.13181310533007e-07 LRRC8D other 9.76118823465384e-37 0.00806613051593805 1 3.48183375212483 -4.98071028105491 2.84947667323717e-15 78.4754337680988 29.9859443651994 2.61707394679137 0.00917625628835539 -152.58671772167 40.9156057591695 -3.72930364565051 0.000217285937740106 PPID other 2.30123736130634e-11 1 1 2.61707394679137 -3.72930364565051 0.0317274945375104 1.60791661918522 4.38926404577621 0.366329435280276 0.714296151229323 9.70292088387939 5.66336589430623 1.71327812205007 0.0873689946123464 COL24A1 other 1 1 1 0.366329435280276 1.71327812205007 2.09879529894512e-17 83.1037064736163 32.0961275385198 2.58921286918119 0.0099405364792487 -185.291677635514 43.7949355460751 -4.23089280358856 2.8377043510812e-05 ETFDH other 1.74451865248318e-13 0.234905166182502 1 2.58921286918119 -4.23089280358856 0.654868655279469 -24.2433199712818 27.3759074866426 -0.885571372679089 0.376335570105631 -30.3454529137251 37.3542291808864 -0.812369939874236 0.417021701837225 RXFP1 other 1 1 1 -0.885571372679089 -0.812369939874236 0.196189697103525 5.61110132158588 18.3736491453342 0.305388509228758 0.760216349330291 66.4827753303965 39.085527301084 1.70095633655562 0.0896658426955179 PTGER4 other 1 1 1 0.305388509228758 1.70095633655562 0.259003602940613 -87.2847119147252 58.5550706948341 -1.49064309681426 0.136776649963406 -134.499203886116 137.38476796329 -0.978996477411922 0.328123374540418 NEUROD2 other 1 1 1 -1.49064309681426 -0.978996477411922 0.781764269874519 82.2848844245433 117.510080630293 0.7002368135839 0.484153755046169 93.3439062047312 183.889533374697 0.507608587023449 0.611985130681731 ECEL1 other 1 1 1 0.7002368135839 0.507608587023449 6.69489447999487e-21 73.2572157760407 89.4932328105769 0.818578270952602 0.413474236666818 -734.973564080301 116.67968393415 -6.29907057766023 7.32469525872586e-10 PLRG1 other 5.77300751009957e-17 6.87349403078835e-06 1 0.818578270952602 -6.29907057766023 4.41746184673313e-62 53.6543837619692 14.1797561965396 3.78387209330602 0.000175988410125323 -100.795977353017 17.6086308227986 -5.72423707256742 1.93567751392489e-08 ZNF584 other 4.28582148370049e-58 0.00017806297450595 1 3.78387209330602 -5.72423707256742 0.0268619390580891 171.083803147756 282.949010751531 0.604645348267332 0.545727759344694 -1119.57372730628 551.078475996343 -2.03160489126726 0.042796827834568 DSCAM other 1 1 1 0.604645348267332 -2.03160489126726 6.55200206295559e-07 -173.711816688817 890.124285985865 -0.195154563720751 0.845362442003871 -3430.01436615313 1137.61804422607 -3.01508435415736 0.00271842810097092 CLSTN1 other 0.00402292926665473 1 1 -0.195154563720751 -3.01508435415736 6.4790394816376e-31 -63.0056063108563 50.3623454412066 -1.25104591056843 0.211588610491703 -438.115040251325 62.9103405317011 -6.96411808533375 1.22305631024162e-11 ZNF274 other 5.88167204143062e-27 1.16679571997051e-07 1 -1.25104591056843 -6.96411808533375 4.79512464525939e-14 27.141015614818 45.2474147125069 0.599835720720544 0.548925905308665 -216.432950131644 57.8281889865721 -3.74268940329257 0.000206311834264095 PIK3CD other 3.79582066918734e-10 1 1 0.599835720720544 -3.74268940329257 1.59871782043527e-39 -13.5312997530488 41.3882633262354 -0.326935673680986 0.743872718988885 -427.2088004072 52.8997491011896 -8.07581902874458 6.55120454270714e-15 SLC25A33 other 1.49096423933793e-35 6.35597864733447e-11 1 -0.326935673680986 -8.07581902874458 3.01179910308765e-13 91.8364738658811 73.5732276302523 1.24823222826939 0.21261285752136 -282.488432126183 94.0438185941348 -3.0037958512225 0.00281919431749452 SPSB1 other 2.34649268121558e-09 1 1 1.24823222826939 -3.0037958512225 4.51545204402195e-50 142.679026377126 24.9320831370373 5.72270778951367 1.94931194956872e-08 -72.9117370133618 31.2713101653005 -2.33158561723028 0.02017620655571 ZIK1 other 4.30999897601895e-46 1 0.000180564765888551 5.72270778951367 -2.33158561723028 0.0026018116006095 -42.9863494600505 51.5869261310881 -0.833279915744883 0.405141039990396 -163.304131227849 65.9520770860158 -2.47610292871998 0.0136594494036078 PLEKHG5 other 1 1 1 -0.833279915744883 -2.47610292871998 8.55884694199721e-08 193.110565358578 57.978888358225 3.3307048621808 0.000939943350236311 -96.3185436067501 72.1920092715624 -1.33419951291883 0.182834905662334 ANO5 other 0.000554527693371999 1 1 3.3307048621808 -1.33419951291883 0.00484147777809097 174.925583250692 53.7357395185901 3.25529312181841 0.00122104366673233 90.0555743308759 109.73606839677 0.820656103745801 0.412290633687344 HDAC3 essential 1 1 1 3.25529312181841 0.820656103745801 8.6891989916261e-27 -198.682766467138 92.4454143341636 -2.14919006960104 0.0321666181329892 -825.944113796314 105.210493627305 -7.85039671729055 3.21871937330124e-14 GPHN other 7.76379929901792e-23 3.11668596916759e-10 1 -2.14919006960104 -7.85039671729055 0.463030033903793 632.574556695726 585.712301940929 1.08000899861503 0.280733867822441 -259.885077211509 1351.8295885635 -0.192246921808888 0.847638096048948 VAT1L other 1 1 1 1.08000899861503 -0.192246921808888 3.74120966503243e-15 11.6762633102316 29.5944157724899 0.394542788071711 0.69337238202227 -157.50014073661 37.814906794162 -4.16502787099095 3.75102298889497e-05 TMEM51 other 3.01728559484866e-11 0.307996497618166 1 0.394542788071711 -4.16502787099095 0.000793777758310768 132.158428376533 116.377413371534 1.13560204293781 0.256747004232074 -140.051616916783 148.910740869176 -0.940507152803868 0.347478253967837 CAMTA1 other 1 1 1 1.13560204293781 -0.940507152803868 0.00906709069225972 8.25752555972549 17.2942248406226 0.477473008233899 0.633264053444375 -68.9880289892583 30.065365916588 -2.29460134231047 0.022229268668627 PAH other 1 1 1 0.477473008233899 -2.29460134231047 8.49506604441503e-13 59.6283716790235 16.0100883689892 3.72442489415117 0.000221459439120969 -67.7982400793203 24.2069507468954 -2.80077572711282 0.00532471818115364 SPATA5L1 essential 6.55139493345287e-09 1 1 3.72442489415117 -2.80077572711282 0.00473015701726676 -988.418060031094 742.4298161506 -1.33132861656326 0.183776577112712 -3554.65062983077 1122.53983728129 -3.16661423655117 0.00165051396012672 GATM other 1 1 1 -1.33132861656326 -3.16661423655117 6.38942264555243e-07 -68.4812808329487 45.5398678994655 -1.5037654695031 0.133381006680677 -199.737960062371 51.6760605532658 -3.86519324274899 0.000128260842957646 SYCE1 other 0.00392885598475019 1 1 -1.5037654695031 -3.86519324274899 2.19555958152917e-26 -19.1760608104518 9.63225913227149 -1.99081654128315 0.0471219677624517 -110.201968912702 13.3901588610756 -8.23007180542518 2.1637723631991e-15 RASGRP4 other 1.9566826990588e-22 2.1040522459748e-11 1 -1.99081654128315 -8.23007180542518 4.97781266828418e-05 11.4984832473078 76.9200983043244 0.149486070621173 0.881238905853186 -402.072886942965 121.394403415432 -3.31212045720926 0.00100264340039416 BCL2 ts 0.256009473174927 1 1 0.149486070621173 -3.31212045720926 1.09852479843245e-28 241.211324965918 48.8579156546577 4.93699581191452 1.12995173230335e-06 -114.89042197965 62.7419952505984 -1.83115665226719 0.0677562843673218 CTPS1 essential 9.89111728508575e-25 1 0.0101164578593119 4.93699581191452 -1.83115665226719 0.0750023353093936 -251.44507273768 275.911911639258 -0.911323730982784 0.362635422139938 -569.138431703129 312.953627229192 -1.81860308424008 0.0696675129096223 KNDC1 other 1 1 1 -0.911323730982784 -1.81860308424008 0.016238537022537 -12.679521276596 28.493236670315 -0.445001086514186 0.656541850529087 33.365100472813 32.5415353499835 1.02530812126632 0.305791594808385 CFAP46 other 1 1 1 -0.445001086514186 1.02530812126632 1.54394464108662e-09 -20.0016233510374 78.569258788572 -0.254573145520709 0.799172280295786 -373.598641778786 100.890583483974 -3.7030080397754 0.000240268179025516 COL8A2 other 1.0909512833918e-05 1 1 -0.254573145520709 -3.7030080397754 3.29130862879113e-08 35.182573409592 26.2706606622442 1.3392344357809 0.181193697461065 -51.7889148054661 29.9899427768906 -1.72687607944931 0.0848998284423211 PWWP2B other 0.000218279588261427 1 1 1.3392344357809 -1.72687607944931 0.449948565118733 -1.59796490071683 5.67756391727598 -0.28145256028813 0.778496837530054 -14.9687731729423 11.9703725876019 -1.25048515101744 0.211793061707067 PCDHB1 other 1 1 1 -0.28145256028813 -1.25048515101744 0.219233826113405 -26.418911889751 16.0233759438002 -1.64877314134124 0.0999127845903498 -36.2743239087767 21.3579137668983 -1.69840202112796 0.0901437231714762 ZNF540 other 1 1 1 -1.64877314134124 -1.69840202112796 1.75414659700844e-62 309.917299624504 83.4533995288242 3.71365697951539 0.000230672424606329 -769.660757312869 106.635613544844 -7.2176708299165 2.35101807908499e-12 EXOSC10 essential 1.70257468705639e-58 2.25486143965041e-08 1 3.71365697951539 -7.2176708299165 3.31755996507326e-37 69.1004817492854 12.6707410722482 5.45354698318563 8.28662650894675e-08 -41.7275803314309 16.8249929106831 -2.48009497257712 0.013511336710928 ZNF570 other 3.07570984361942e-33 1 0.000759635052075148 5.45354698318563 -2.48009497257712 2.04355930522758e-12 174.3861020161 38.1248635566151 4.57407806213229 6.27268933042378e-06 -48.151054660488 43.6962534630292 -1.10194927126253 0.27110300306707 MLLT3 other 1.56373158036014e-08 1 0.0548734862625472 4.57407806213229 -1.10194927126253 1.99015775013276e-08 94.9823576956304 16.568344643348 5.73276086055855 1.85241539447473e-08 -27.3952238500915 11.7840233482301 -2.32477677958828 0.0205443852251077 MRM3 other 0.00013387791185143 1 0.000171626286298084 5.73276086055855 -2.32477677958828 1.2883027501949e-23 -114.321784963903 100.778105487317 -1.13439109031764 0.257253828246261 -867.772081221971 122.063079156036 -7.10921014955455 4.8034940634853e-12 PTEN ts 1.1316451357712e-19 4.59550277053638e-08 1 -1.13439109031764 -7.10921014955455 4.44433681739177e-05 660.763232204578 264.357836367263 2.49950310263019 0.0128042280364597 -522.014186640161 399.732106411279 -1.30591007894439 0.192273300476103 FRMD5 other 0.23017220377272 1 1 2.49950310263019 -1.30591007894439 0.0122449831893707 3771.84954495029 5460.08419950114 0.690804281973325 0.49005869290172 -18619.468079911 9523.69948335219 -1.95506673771663 0.0512181451422331 AQP4 other 1 1 1 0.690804281973325 -1.95506673771663 0.0452912388148133 -99.9472678900351 245.534073305411 -0.407060684264844 0.684162269516791 -899.154285194527 407.163803541913 -2.20833550864 0.0277381563385053 TLN2 other 1 1 1 -0.407060684264844 -2.20833550864 5.91722474778868e-05 -2.4928661274897 3.98101218505482 -0.626189022190942 0.531517152995591 13.1415417480977 2.95473362184324 4.44762318029183 1.10214201615391e-05 LGALS9C other 0.301660117642267 0.0931640646254904 1 -0.626189022190942 4.44762318029183 0.000495618733747653 67.678291964662 18.5918881569695 3.64020541610733 0.000304949647308985 -22.9946992006732 14.030467383337 -1.63891184608592 0.101949673597429 TVP23B other 1 1 1 3.64020541610733 -1.63891184608592 0.0515549637843783 -0.783423659745754 2.72518373711911 -0.287475537548136 0.773884190870504 -4.9628028409513 2.05657441645683 -2.41314041507015 0.0162253801574856 FBXW10 other 1 1 1 -0.287475537548136 -2.41314041507015 2.28871103668674e-08 84.8689559163926 16.3258068920098 5.19845398624244 3.08897757328461e-07 33.6898407071673 12.1171220496722 2.78035003436139 0.00566405713891303 ATPAF2 other 0.000153412300789112 1 0.00280262935224112 5.19845398624244 2.78035003436139 3.03674382472047e-59 154.003611102826 19.582652405403 7.86428763145159 2.92070562783503e-14 -70.5226966059497 25.1475051227811 -2.80436155640995 0.00526586574480993 PPIH essential 2.9365312785047e-55 1 2.82665890661874e-10 7.86428763145159 -2.80436155640995 0.972059635530716 3.1853992543003 44.4878567329428 0.0716015445163386 0.942951693078892 7.34033986167134 33.0191820427099 0.222305320954853 0.824179830506997 DRC3 other 1 1 1 0.0716015445163386 0.222305320954853 7.07422155118398e-17 599.275514397023 218.593039856202 2.7415123317341 0.00636608851943456 -916.902105141221 281.512203917713 -3.25705988010819 0.00121323973846026 JMJD1C other 5.85038122282915e-13 1 1 2.7415123317341 -3.25705988010819 0.76443746939315 -91.0016580485811 449.486230885536 -0.202457053844115 0.839653650437255 -627.101871627718 865.872302493524 -0.724242904896948 0.469304169824827 SYNPO other 1 1 1 -0.202457053844115 -0.724242904896948 5.27605663366379e-06 59.5215572934938 22.2285786437649 2.67770415047161 0.00769146315625715 -38.3877469231782 30.0983051097247 -1.27541224607944 0.202839404772811 RAB33B other 0.0301632157746559 1 1 2.67770415047161 -1.27541224607944 0.0537700806529812 8.19148236943739 4.80038617102148 1.70642154143493 0.0886635837340962 -11.0153739256718 11.203348910462 -0.983221536141335 0.326060447140362 ANKRD20A4 other 1 1 1 1.70642154143493 -0.983221536141335 0.0313597235993597 3552.01093799682 1344.82498043429 2.64124402035554 0.00855632256867762 3040.3198273904 2671.17420014017 1.13819601403415 0.255662253552192 GAP43 other 1 1 1 2.64124402035554 1.13819601403415 0.00631816299686754 -3.27695904528176 11.893301040485 -0.275529815828839 0.783039160312831 22.7182724464312 15.344804629574 1.48051884627103 0.139453776818707 EPHX4 other 1 1 1 -0.275529815828839 1.48051884627103 0.0618625956192009 1038.37056599245 511.150942622411 2.03143627333481 0.0428153721114982 166.623131864845 797.025436355819 0.209056228652731 0.834501757913657 LAMB2 other 1 1 1 2.03143627333481 0.209056228652731 1.61382822719772e-12 177.028989856554 86.5046021361279 2.04646903731171 0.0413080642844693 -637.815197167035 134.884556625507 -4.7286006131737 3.05516994660539e-06 USP19 other 1.23732210179249e-08 0.0264577717376026 1 2.04646903731171 -4.7286006131737 4.3914834514089e-06 282.053897849467 65.8162725832137 4.28547358850893 2.24489800582451e-05 -238.016397849462 148.908951186129 -1.59840221795635 0.110676243894216 ORMDL3 other 0.0253169020973723 1 0.192230616238753 4.28547358850893 -1.59840221795635 0.000111638472994625 29.6112109638285 17.8569266385846 1.65824789243663 0.0979866575395463 -58.4441698494716 27.7977531382321 -2.10247819522828 0.0360842240984954 NME6 other 0.550489310336497 1 1 1.65824789243663 -2.10247819522828 0.0469015783707512 -2.52975839717141 8.44933037563878 -0.299403418342504 0.764774273766326 42.2834338123083 18.3556772165183 2.30356163455834 0.0217147388773293 SLFN12 other 1 1 1 -0.299403418342504 2.30356163455834 0.566399409546104 -34.5468971203665 45.5683625199475 -0.758133389261982 0.448778849798867 49.6412747553629 108.754633257275 0.456452045017054 0.648291205150724 CALB2 other 1 1 1 -0.758133389261982 0.456452045017054 0.0312578026907025 123.192528735631 78.4595636029171 1.57014037650155 0.117106202817177 -218.625084516566 168.595194155077 -1.29674564931828 0.195402996716808 FRMD3 other 1 1 1 1.57014037650155 -1.29674564931828 1.83631072895487e-08 47.6876493331593 8.34108062196788 5.71720278156339 2.01167408450507e-08 -6.56570659020805 17.3118968714968 -0.37925980260535 0.704679584474426 TEFM other 0.000123785706238848 1 0.000186240786743479 5.71720278156339 -0.37925980260535 0.000358901046535709 71.5865586457484 36.9576255728478 1.93699020259413 0.053389244163355 -86.9382645276044 59.507560552804 -1.4609616613415 0.144742936420445 MALT1 other 1 1 1 1.93699020259413 -1.4609616613415 0.886736320912195 -5.49139130068262 26.1543888581834 -0.209960604717568 0.833796049366576 -24.244868498693 49.7765521275217 -0.487074083327036 0.626449493453321 ISG20 other 1 1 1 -0.209960604717568 -0.487074083327036 0.0333523106400602 10.4034710304319 4.72393945542486 2.2022871225593 0.0281654072510203 20.5643351891689 9.00408684355262 2.28388903244464 0.0228559019843161 MBOAT1 other 1 1 1 2.2022871225593 2.28388903244464 9.33837919021479e-06 4057.82632762078 1081.75119085595 3.75116418814383 0.000199671410623402 -2043.49700944569 2061.87690538625 -0.991085842276741 0.322190853111084 ID4 other 0.0521081558813985 1 1 3.75116418814383 -0.991085842276741 6.04894416219618e-08 67.0310452694325 31.2428144901224 2.14548677394685 0.0324720115956423 -275.470247299768 71.1880076799643 -3.86961591253099 0.000125868235708591 PAIP1 other 0.000394572627700057 0.992596906797946 1 2.14548677394685 -3.86961591253099 0.0039131026262014 25.4345157292097 8.36598902585252 3.04022819664384 0.00250808280570455 2.83999881957195 19.0622420144375 0.148985560954529 0.88163471051155 C5orf34 other 1 1 1 3.04022819664384 0.148985560954529 0.310552587447075 -40.9294105115802 26.974408197512 -1.51734229762844 0.129904994049166 -35.2272994714795 35.176642611492 -1.00144007091714 0.317169557908401 C1QTNF4 other 1 1 1 -1.51734229762844 -1.00144007091714 1.01558262189159e-11 56.3116626029967 18.3453788781842 3.06952846146781 0.00227753684026639 -82.2669426303827 27.2068892502032 -3.02375408940837 0.00264363273550477 SERHL other 7.65444622119691e-08 1 1 3.06952846146781 -3.02375408940837 0.33643516297152 -67.0000701866425 162.962769772319 -0.411137281725455 0.681172955432329 86.5699260759203 209.272319338177 0.413671174236982 0.679317411125187 NEGR1 other 1 1 1 -0.411137281725455 0.413671174236982 0.000349718102362642 99.9343681756479 45.2403276385413 2.20896649940509 0.0277023253484507 -203.15567490999 103.081903597219 -1.97081803711929 0.0493841566879817 ZNF131 essential 1 1 1 2.20896649940509 -1.97081803711929 1.01812492737289e-10 4087.42521402393 588.275816472026 6.94814422006467 1.36196212830258e-11 3415.07592397514 1711.72195831174 1.99511135987495 0.04665553331068 BSG other 7.49238134053707e-07 1 1.30326156057274e-07 6.94814422006467 1.99511135987495 0.113798344958685 97.4679968006014 70.6795634555492 1.37901243351481 0.168597922810931 -161.01020269 145.441654494789 -1.10704325558789 0.268885617122485 COPRS other 1 1 1 1.37901243351481 -1.10704325558789 3.59059896572128e-57 33.4883601473824 11.6788726869104 2.86743087669034 0.00433791262667404 -114.435866423561 15.0689793480621 -7.59413519524654 1.88950153990698e-13 ALG14 other 3.46385082223132e-53 1.82242423524028e-09 1 2.86743087669034 -7.59413519524654 0.000185371073245525 19.1183042108273 62.8260491562131 0.304305371220954 0.761039776047852 -344.938269836725 104.744732012991 -3.29313239155496 0.00107109833842887 SUCLG2 other 0.887371327626328 1 1 0.304305371220954 -3.29313239155496 0.453362082596594 -13.0524984623694 12.6126519510116 -1.03487343605978 0.301301664945089 -28.3053779571265 24.7281348540616 -1.14466287587709 0.252976816454125 STARD5 other 1 1 1 -1.03487343605978 -1.14466287587709 1.56556951587521e-06 -22.5622481869596 351.589727705243 -0.0641720915290073 0.948862542712288 -2178.62788074135 533.907263730149 -4.0805361319124 5.34183944382101e-05 CSDC2 other 0.00934331887074325 0.434024454810457 1 -0.0641720915290073 -4.0805361319124 0.709973309081957 66.7821040150975 252.135227146477 0.264866217905762 0.791237407244392 -362.748045874388 583.375091450706 -0.621809280496234 0.534391539722961 RCAN2 other 1 1 1 0.264866217905762 -0.621809280496234 0.227527753835626 -27.3748428616438 41.2845779155666 -0.663076728497253 0.507631815250415 -138.139844886817 80.9417887732375 -1.70665668476666 0.0885979199769337 IL16 other 1 1 1 -0.663076728497253 -1.70665668476666 0.673465820294314 -6.23037564163659 21.7296597073305 -0.286722191030666 0.774460624420385 -27.5133422080519 33.5582690228438 -0.819867740774205 0.412737429580195 CFAP53 other 1 1 1 -0.286722191030666 -0.819867740774205 4.0748526501265e-31 561.283768987683 212.341017716563 2.64331298316039 0.00850436426424712 -1227.87174531373 272.682511043833 -4.50293544904445 8.60471110153344e-06 GNG12 other 3.70281860316995e-27 0.0731056255186281 1 2.64331298316039 -4.50293544904445 0.0347789417701642 -10.9379291240425 10.9834540754414 -0.995855133450168 0.319871631888853 -37.5810285126334 15.1821685035522 -2.47533996898009 0.0136891220721152 MYOZ2 other 1 1 1 -0.995855133450168 -2.47533996898009 0.000121559386468843 -297.589435881195 146.037488621639 -2.03776056880985 0.0421756537204346 -846.879487128743 201.864162663257 -4.19529388453898 3.30186120592508e-05 SYNPO2 other 0.596370350016146 0.272106381980286 1 -2.03776056880985 -4.19529388453898 0.000620037285486495 6.8274210420542 2.41473192737309 2.82740330910418 0.00490828874873961 -0.961864690635371 3.68755299349121 -0.260840913292129 0.794338064820094 DNAJB7 other 1 1 1 2.82740330910418 -0.260840913292129 0.00018758110197095 43.8053538020059 10.5319255538044 4.15929200963469 3.84595941293624e-05 23.171839320295 25.1163338988185 0.922580477455152 0.356736119270418 CLP1 essential 0.897012829625083 1 0.325752762275699 4.15929200963469 0.922580477455152 0.200817062801889 9.25606305578248 32.487651479996 0.284910193076955 0.775847918330614 112.81143896524 65.6549004460149 1.71824857244281 0.0864595972240322 RSPH9 other 1 1 1 0.284910193076955 1.71824857244281 5.3836036553469e-07 344.222646623954 114.212497839749 3.01387898115083 0.00272902811921178 -170.20959459924 168.033859891145 -1.01294819216499 0.311644136051166 COPS9 other 0.00332652869863885 1 1 3.01387898115083 -1.01294819216499 2.27052129099872e-06 186.542035316332 48.2600506462192 3.86535100602813 0.000127726281599518 -218.429108207158 120.140952983353 -1.81810700500623 0.0697307212525233 GTPBP2 other 0.0133892640530195 1 1 3.86535100602813 -1.81810700500623 5.02525161804866e-05 64.9000693470346 14.4624260318055 4.48749533475972 9.22265174843417e-06 67.0413227771737 18.5711641351884 3.60996878220168 0.000341625479398633 FGGY other 0.258348185683882 1 0.0802186249078804 4.48749533475972 3.60996878220168 3.9272076754594e-05 665.953270281491 554.374920910513 1.20126875362204 0.230306672098103 -1297.30287887018 683.518132626802 -1.89797873230453 0.0583667549994738 IL17D other 0.204921696505471 1 1 1.20126875362204 -1.89797873230453 0.00213482878444538 -251.223576065407 222.153313740129 -1.13085675759617 0.258738474743162 -979.810837384898 311.945642862407 -3.14096657479865 0.00179882232445964 FUT9 other 1 1 1 -1.13085675759617 -3.14096657479865 3.58273690067811e-10 647.491003659539 153.866240547361 4.20814209378331 3.12656124522237e-05 -876.630797641627 333.562089003799 -2.62808882226314 0.00888891374460749 ZNF24 other 2.59246842133068e-06 1 0.266039096355971 4.20814209378331 -2.62808882226314 0.00111968149091628 74.3076324989514 39.2017175770554 1.89551981626548 0.0586861747928638 -49.4154887428332 55.4110320459712 -0.891798743287008 0.372993839528964 MANEA other 1 1 1 1.89551981626548 -0.891798743287008 4.08957308198223e-05 52.4738541591927 130.91960074474 0.400809763096538 0.688755632730568 -592.556315810186 191.668785610603 -3.0915639910926 0.00211816611793975 AFF1 other 0.213066757571274 1 1 0.400809763096538 -3.0915639910926 2.3674234531247e-05 73.1857123188658 16.6127966043478 4.40538183075762 1.32919970211101e-05 13.19645704976 35.299229639222 0.373845468715188 0.708700182971688 BANP essential 0.126586132038578 1 0.114922606244518 4.40538183075762 0.373845468715188 0.294332571848215 -25.4499209918565 26.3964406698018 -0.964142147428682 0.335507881692844 -75.1566488391878 48.4382591180698 -1.55159682052138 0.121482606731517 NIPAL4 other 1 1 1 -0.964142147428682 -1.55159682052138 0.618485740208983 -10.4566062963419 28.7041080459271 -0.364289539309536 0.71581801105303 -51.1132855232772 52.6728978605178 -0.970390610720326 0.332388606625428 FNDC9 other 1 1 1 -0.364289539309536 -0.970390610720326 0.00136793589141944 -96.1953023217087 86.0554694358217 -1.11782903460249 0.26425556950405 -463.274148532378 134.932965299639 -3.43336520844709 0.000653111136505129 RASGRP1 other 1 1 1 -1.11782903460249 -3.43336520844709 3.21250691060143e-18 134.783912377813 38.4594493613791 3.50457207827739 0.000504437461095631 -109.041750088329 46.6242399873433 -2.33873517547802 0.0197980286873457 CHCHD1 essential 2.69593579937672e-14 1 1 3.50457207827739 -2.33873517547802 7.51445895039474e-10 242.884143143853 59.6961548290531 4.068673163948 5.60851641323206e-05 -122.624402930286 89.017100277848 -1.37753760285989 0.169049563431627 MRPL52 other 5.37884971669255e-06 1 0.471956656173478 4.068673163948 -1.37753760285989 2.2708596594985e-06 8.95060022627384 19.5034533098536 0.45892386769023 0.646517533247506 -72.5439882257528 25.2820203063599 -2.8693904738105 0.00431254847817545 SMPDL3A other 0.0133892640530195 1 1 0.45892386769023 -2.8693904738105 0.000151675558811352 -156.963896900434 84.6982881062722 -1.85321215351471 0.0645242650753852 -537.077349563509 129.323667816153 -4.15297028481298 3.94636534412327e-05 RND1 other 0.735474784676248 0.323207321683696 1 -1.85321215351471 -4.15297028481298 8.92816349017584e-08 41.688228712755 15.45177270956 2.69795767102907 0.00724609784650023 -16.2283888823458 18.7321236003929 -0.866340049240623 0.386778024017455 AGAP5 other 0.000577920022719082 1 1 2.69795767102907 -0.866340049240623 1.25101350626114e-34 105.107054969711 71.3601856145463 1.47290893464668 0.141495465692197 -675.563877167357 92.3392867414948 -7.31610456401518 1.23147919902536e-12 WASHC2C other 1.15055712170837e-30 1.18332836234347e-08 1 1.47290893464668 -7.31610456401518 0.296158386927658 5.73054517875399 17.3460031304276 0.330366894071507 0.741281077259777 27.1196711876346 22.445535183038 1.20824346430059 0.227607046651177 ZFAND4 other 1 1 1 0.330366894071507 1.20824346430059 0.402880410302012 -9.74172269410269 8.93542161950878 -1.09023648899046 0.276209774279056 -15.5078789328873 11.4958452607761 -1.34899858001745 0.178035994311829 THEMIS other 1 1 1 -1.09023648899046 -1.34899858001745 0.393897801874793 -41.7000589275183 65.6632645302375 -0.635059179982069 0.525721422348795 143.376773491682 142.649610692821 1.00509754492375 0.315404817508302 SLFN11 other 1 1 1 -0.635059179982069 1.00509754492375 0.185485100419478 10.2656681546352 7.26774731929015 1.41249656924477 0.158515551049622 15.0697243518826 8.27972569311676 1.82007531534657 0.0694314733895639 FAM71D other 1 1 1 1.41249656924477 1.82007531534657 0.269062179166843 -7.74773924999897 14.9363862719434 -0.518715779636228 0.604223940803832 -27.1162325056821 17.414711585651 -1.55708765960987 0.120180243761994 CCL19 other 1 1 1 -0.518715779636228 -1.55708765960987 1.4035913539617e-19 48.148858190024 86.9537309837559 0.553729640410931 0.580046445976603 -567.225056422965 105.578403733909 -5.37254813827791 1.26351607395939e-07 LRRC20 other 1.19389480567983e-15 0.00114398745336283 1 0.553729640410931 -5.37254813827791 0.475272143520196 3.68949578050126 3.66649212066562 1.00627402407494 0.31483935322017 8.80562034406236 8.60809546317743 1.02294640919468 0.306897828904605 TMEM217 other 1 1 1 1.00627402407494 1.02294640919468 0.000253904022441222 -2.05321935750726 115.070916843815 -0.0178430781106409 0.985772201065172 -872.877567902937 235.10745760607 -3.71267494783373 0.000231668356792423 TMCC1 other 1 1 1 -0.0178430781106409 -3.71267494783373 2.47359757491841e-18 159.695014089265 30.6659358933927 5.20757020573022 2.94948113024904e-07 -37.843195818555 37.0817182340341 -1.02053512136938 0.308038084584128 NAA16 other 2.0798008409914e-14 1 0.00267753897004008 5.20757020573022 -1.02053512136938 0.846079961253087 -6.17344547083967 20.0898635337975 -0.307291558275346 0.758768181605342 -23.5835910263733 41.0466594743039 -0.574555672213403 0.565888161686218 EFCAB12 other 1 1 1 -0.307291558275346 -0.574555672213403 6.59554874915837e-06 225.140399002495 126.315268943567 1.78236883700165 0.0753832747447618 -1155.02560266001 305.902145769681 -3.77580091749225 0.000181545686918305 FAM192A other 0.037317614822738 1 1 1.78236883700165 -3.77580091749225 0.065185535906079 -20.0306080242659 20.386268171771 -0.982553935594863 0.326371930280426 -97.6323984164188 41.652259418825 -2.34398805199733 0.019526944131201 RAB43 other 1 1 1 -0.982553935594863 -2.34398805199733 0.0156901127360497 68.5785791479442 30.880391119849 2.22078078227007 0.0268766484164682 -9.7329144201721 48.1480466057124 -0.202145571966306 0.839896777990893 RARG og 1 1 1 2.22078078227007 -0.202145571966306 0.381354717456492 -32.7017207594043 25.3850651641688 -1.28822678011333 0.198347141754096 1.96578826200156 58.5879870271367 0.0335527530770268 0.973249083210029 CES4A other 1 1 1 -1.28822678011333 0.0335527530770268 0.148131952951883 -7.07917420681223 9.17574958305999 -0.771509089555103 0.440821257295543 29.8946592568002 21.1773613366722 1.41163286499874 0.15876806972745 CES3 other 1 1 1 -0.771509089555103 1.41163286499874 0.0677600536454354 10.2236023514555 60.1001410720919 0.170109456801308 0.865002600420323 -292.877144702976 138.709365632471 -2.11144462645005 0.0352999753289454 CES2 other 1 1 1 0.170109456801308 -2.11144462645005 3.94811037274937e-05 -6.39191981925074 39.2312095639806 -0.162929460760735 0.870649118191611 -390.88187402513 90.5444828338549 -4.31701481737303 1.95742194951189e-05 PDP2 other 0.205972918146335 0.163092396833331 1 -0.162929460760735 -4.31701481737303 8.62963443465859e-05 61.2920302856388 79.2166918624408 0.773726203968123 0.439511071258653 -414.224023970141 132.654861748633 -3.12256948980167 0.00191190477952144 ZNF621 other 0.430618758289464 1 1 0.773726203968123 -3.12256948980167 0.517502829542799 63.7855510780604 60.4269236315114 1.05558163885738 0.291742614639706 0.878232624319018 126.509033090018 0.00694205467283992 0.994464254152729 EGFL7 other 1 1 1 1.05558163885738 0.00694205467283992 2.85714262102427e-06 211.912599601591 148.017118791306 1.43167629076995 0.152951286115527 -354.595291909288 176.551543442566 -2.00845195116996 0.0452100463965146 NBEA other 0.0167028557625079 1 1 1.43167629076995 -2.00845195116996 0.661693508188566 -25.3990090946117 83.635772146069 -0.303685952109734 0.7615113673323 -125.585124353348 142.276216320254 -0.882685297665383 0.377890508820816 MYD88 other 1 1 1 -0.303685952109734 -0.882685297665383 6.81929531733427e-05 126.104316546763 61.6490371731784 2.04551964360001 0.0414005382128446 -225.892885691446 104.873686506627 -2.15395198944563 0.0317888396737454 OXSR1 other 0.345056343057114 1 1 2.04551964360001 -2.15395198944563 0.0624268234768229 -5.62573469148861 9.61149676300211 -0.585313071440023 0.55863934109418 -35.683733364556 15.8554761783059 -2.25056207478523 0.0249097634269493 GXYLT2 other 1 1 1 -0.585313071440023 -2.25056207478523 1.14082880729855e-06 -463.543542453464 259.677273782518 -1.78507551200528 0.0749409679638183 -1342.10899889007 313.154260623986 -4.28577595021638 2.24093396559227e-05 HPSE2 other 0.00688033853681753 0.186221612540718 1 -1.78507551200528 -4.28577595021638 0.000376565996643975 252.441184745419 179.755801645366 1.40435625684812 0.160921493532834 -1375.58078866142 402.591507014439 -3.41681522012854 0.000692737965858483 DCAKD other 1 1 1 1.40435625684812 -3.41681522012854 0.000506774883704626 -184.222208495988 163.910545613699 -1.12391919510877 0.261662909355392 -1109.55055920674 291.861505162397 -3.80163378719426 0.000164115594225737 ARPP21 other 1 1 1 -1.12391919510877 -3.80163378719426 5.43262729022692e-09 -79.6470848633116 46.8703593825096 -1.69930604144318 0.0899731969680771 -442.443067860001 74.4500592655325 -5.94281686575951 5.73107118431382e-09 TADA2B other 3.75340219481778e-05 5.31041055938518e-05 1 -1.69930604144318 -5.94281686575951 0.0739398528630654 2.92173143171722 18.8315927022299 0.155150521674741 0.876774289349558 -53.1657765846957 29.9125761188119 -1.77737204490589 0.0762024704231305 CCDC96 other 1 1 1 0.155150521674741 -1.77737204490589 0.35598024493459 15.2520303339966 12.3275056851261 1.23723571690574 0.216662477864281 2.19628779365183 19.5800970107089 0.112169403065297 0.910740475825311 EVC2 other 1 1 1 1.23723571690574 0.112169403065297 0.203590013233971 70.5060755967527 39.627868853914 1.77920432351963 0.0759028309018437 52.9329122840721 83.9174481814598 0.630773616585815 0.528519049638712 FAM222B other 1 1 1 1.77920432351963 0.630773616585815 0.0138669516868015 -10.2826163727458 12.5122884039865 -0.821801419592417 0.411637036211004 -36.5076790930026 14.097980892026 -2.58956792271238 0.00992971180685044 BNC2 other 1 1 1 -0.821801419592417 -2.58956792271238 0.0671119233896738 -45.3161230875165 40.180678806507 -1.1278087984959 0.260018089642881 -129.531085774462 57.355835087569 -2.25837677329077 0.0244134291949689 HPSE other 1 1 1 -1.1278087984959 -2.25837677329077 0.00784230162886475 15.8686043803609 16.5202185101081 0.960556567133269 0.337305128655482 -35.5867515871967 23.5817551276141 -1.5090798540913 0.131999368928411 COQ2 essential 1 1 1 0.960556567133269 -1.5090798540913 4.00988993672867e-08 61.2839451819169 10.6563704181703 5.75092107134536 1.67666555392601e-08 18.8707003793446 29.5648487986287 0.638281646825803 0.523627005527695 ADCK5 other 0.000264372043528521 1 0.000155477196815559 5.75092107134536 0.638281646825803 1.96229105504374e-19 86.5338095907397 49.0751421265752 1.76329208313958 0.0785581471080246 -294.246127098395 60.0365242409968 -4.90111862434343 1.35044870141983e-06 MRPL57 other 1.66716248036516e-15 0.0118609909445704 1 1.76329208313958 -4.90111862434343 4.75300969638325e-07 99.8752363503111 30.6207384311618 3.26168608163515 0.00119428283908364 8.98397068523262 36.7128523986647 0.244709144026068 0.806796508480698 NOC3L essential 0.00294306360400051 1 1 3.26168608163515 0.244709144026068 0.00325189089394387 61.5176879463213 23.149354061076 2.65742567952507 0.00816728768720259 0.170474003982901 35.376657940958 0.00481882726930887 0.99615738176346 ADAMTS20 other 1 1 1 2.65742567952507 0.00481882726930887 0.000494635742071652 -226.520243153924 119.216984504059 -1.9000668746676 0.0580807900076651 -908.366122015385 230.82407583577 -3.93531792004957 9.66055272691546e-05 ADCY5 other 1 0.769946052335163 1 -1.9000668746676 -3.93531792004957 0.785978259256503 -153.067221435318 275.358697521883 -0.55588300937236 0.578574671088127 -334.633523876977 533.140618706604 -0.627664657569696 0.530550728885717 PARP14 other 1 1 1 -0.55588300937236 -0.627664657569696 0.820234381671996 -3.47178942398492 7.21023786736008 -0.481508306362722 0.630395753136378 -8.1524180493728 13.9602297375068 -0.583974490582327 0.559538094463015 PARP15 other 1 1 1 -0.481508306362722 -0.583974490582327 0.554681216114456 -42.9567857821711 81.4902019089788 -0.527140500034005 0.598383228367023 -136.063961224102 125.803006452557 -1.08156366895266 0.280086867540765 ABCD2 other 1 1 1 -0.527140500034005 -1.08156366895266 0.108175697963506 -191.53121721372 218.822453839246 -0.875281370139578 0.381901646062015 -891.248515250298 421.530825471095 -2.11431397515058 0.0350542224028412 ABLIM3 other 1 1 1 -0.875281370139578 -2.11431397515058 0.000123741670085568 2.77574001873171 5.73529091108351 0.483975453340574 0.628645176466527 -19.804667968703 7.86549850359542 -2.51791643716542 0.0121607227728047 MFSD4B other 0.605715475068857 1 1 0.483975453340574 -2.51791643716542 8.11565162706944e-17 40.6328923449631 32.8531025792093 1.23680532902476 0.216822099217291 -155.669695785813 41.9869921859033 -3.70756959909307 0.000236112638417681 VANGL1 other 6.7083976349356e-13 1 1 1.23680532902476 -3.70756959909307 0.0629651617546802 37.6052838416886 28.2017857479821 1.33343626455921 0.18308331255956 -59.8178798711991 54.6051971527237 -1.09546129288566 0.273917958070484 IQCB1 other 1 1 1 1.33343626455921 -1.09546129288566 0.00283575460460893 -133.312973808981 167.951099982329 -0.793760647134835 0.427765578504047 -1085.07913085369 325.192277131177 -3.3367309347755 0.000920130132759321 GOLGB1 other 1 1 1 -0.793760647134835 -3.3367309347755 3.34039813291336e-10 66.4225714110105 10.0600750949107 6.6025920069536 1.18527161121077e-10 65.0598689393529 11.5898141402161 5.61353859106318 3.54616202397267e-08 DMRT2 other 2.41978440748244e-06 0.000324899364636376 1.12683772077808e-06 6.6025920069536 5.61353859106318 0.0317620637567929 -1.82015944515962 12.4760488481297 -0.145892298701002 0.884073528984488 -64.0156406406399 25.8072528507132 -2.48052905944504 0.0134934028163767 ZNF483 other 1 1 1 -0.145892298701002 -2.48052905944504 0.00115437861016292 -173.170969112873 191.494025297639 -0.904315259150844 0.366326511286723 -646.443420204821 230.232943730464 -2.8077798499663 0.00521180570091452 SNCG other 1 1 1 -0.904315259150844 -2.8077798499663 0.0260512733213812 -46.2215291391905 55.3211605482172 -0.835512644368774 0.403885700190721 53.287168062734 66.5125380481448 0.80115974561311 0.423474549479272 MMRN2 other 1 1 1 -0.835512644368774 0.80115974561311 0.149995506734977 69.2821303610734 42.6872671398947 1.62301629977909 0.105305397137026 -19.1461241568363 85.2708987498245 -0.224532923160678 0.822447357573517 ZBTB21 other 1 1 1 1.62301629977909 -0.224532923160678 0.000492265822641467 51.8308089208744 87.6697326067116 0.591205281227314 0.554687855755454 -265.544152890457 115.802293494858 -2.29308198375404 0.0223162899762717 STOX2 other 1 1 1 0.591205281227314 -2.29308198375404 5.12993272653694e-14 563.968545364182 1013.41045411145 0.556505553180486 0.578151465365928 -4968.91730058709 1296.54008065877 -3.83244403679553 0.00014557755832729 C1QB other 4.05931576650868e-10 1 1 0.556505553180486 -3.83244403679553 4.28624181003241e-13 893.876140317892 663.929721627485 1.34634150452964 0.178893532528042 -2504.86809931344 849.420381779468 -2.94891452223685 0.00336081546467361 C1QA other 3.32826676549017e-09 1 1 1.34634150452964 -2.94891452223685 0.347701535370495 38.4461719488449 70.7330440192028 0.543539055641483 0.587035868682737 -67.1734418703333 98.6119389316277 -0.681189748402653 0.496112235266783 NDNF other 1 1 1 0.543539055641483 -0.681189748402653 1.23955981403437e-05 221.592137326694 444.098351380829 0.498970862282422 0.618050989421682 -2482.68656143088 692.471934959679 -3.58525224791304 0.000374730274804614 DAG1 other 0.0682501633607327 1 1 0.498970862282422 -3.58525224791304 5.1362290919155e-07 -18.8209743258365 36.5285090088495 -0.515240693817447 0.606644771787364 116.380526091822 46.9061646313821 2.48113498527139 0.0134708112985364 DAB1 other 0.00317675769334974 1 1 -0.515240693817447 2.48113498527139 0.874694641533367 -36.8100042624198 149.177946701445 -0.246752318800104 0.805215785275362 -93.5392303227237 185.719419920317 -0.503658854646738 0.614754920033817 SAA1 other 1 1 1 -0.246752318800104 -0.503658854646738 2.98073813379415e-32 172.15076969735 48.6109586565789 3.54139836890569 0.000440696114729133 -231.505854701253 62.1159527379279 -3.72699515176069 0.000219162183151697 MINOS1 other 2.7208177685273e-28 1 1 3.54139836890569 -3.72699515176069 9.53854952421123e-05 1.09555887890411 28.4781884266679 0.0384701042949133 0.96933047526223 -168.439398592621 47.4434795387529 -3.55031714010428 0.000426634133602273 THAP2 other 0.474065911353298 1 1 0.0384701042949133 -3.55031714010428 0.00165301461999016 265.094057420567 205.816223245489 1.2880134191578 0.198422890244672 -592.892657882935 320.371761515364 -1.85063956660395 0.0648960899221054 SMARCC1 other 1 1 1 1.2880134191578 -1.85063956660395 7.76660666160616e-29 52.9851905158702 16.612951668572 3.18939051728576 0.0015283252455484 -54.2287579223796 20.7269333345059 -2.61634256487429 0.00919562700102561 ZNF417 other 6.99693594144099e-25 1 1 3.18939051728576 -2.61634256487429 0.0312286740396644 -202.666705399509 98.4554715719433 -2.05846056256423 0.0401369010497317 -419.711251272372 162.597172818294 -2.58129488968058 0.0101671378667897 PTPRM other 1 1 1 -2.05846056256423 -2.58129488968058 0.00755322765663813 396.411123070363 271.274096237524 1.46129368254634 0.144656815839692 -766.991187072452 497.18621731957 -1.54266381559701 0.123639493597753 PEAK1 other 1 1 1 1.46129368254634 -1.54266381559701 0.0214591520112829 -85.4722195546445 101.976051360625 -0.838159728820867 0.402399195452721 -420.023320929113 159.00881727139 -2.64150962277918 0.00854972411094128 MST1 other 1 1 1 -0.838159728820867 -2.64150962277918 2.12153025300272e-05 60.9057599387058 50.9737824527707 1.19484482037678 0.232797215125479 -232.879085775013 78.7285326554944 -2.95800109464838 0.00326484111729945 GMPPB essential 0.113968605191306 1 1 1.19484482037678 -2.95800109464838 4.83331828245125e-08 215.209915933745 81.7167568339494 2.63360813952831 0.00874729856004717 -274.774690416076 121.464419256397 -2.26218255599658 0.0241753818453867 MOB1B other 0.000317355678425749 1 1 2.63360813952831 -2.26218255599658 3.16805662663451e-06 60.8258732935405 39.2006110833693 1.55165625260739 0.121471705016563 -202.054967448734 66.7676689909491 -3.02623965314896 0.00262312691085526 ZNF622 other 0.018453929850146 1 1 1.55165625260739 -3.02623965314896 0.711320456721861 -171.094827358012 800.647808344242 -0.213695492043924 0.830884420321357 -1078.077266316 1389.13962653845 -0.776075525973172 0.438125166883667 CSPG4 other 1 1 1 -0.213695492043924 -0.776075525973172 4.07344938596021e-06 123.874860690973 67.506659200874 1.83500208953266 0.0671880206456901 -328.824444090643 117.130998923072 -2.80732211894313 0.0052201229143922 SNX33 other 0.0235283789122087 1 1 1.83500208953266 -2.80732211894313 9.9170703673928e-49 250.258115558716 56.8750707060917 4.40013722096194 1.36172489590236e-05 -271.770867326349 71.5396043785838 -3.79888691986822 0.000165984387571897 CCDC106 other 9.44303440383143e-45 1 0.117680265503882 4.40013722096194 -3.79888691986822 0.000313375976564055 89.5387596899228 37.7671097420266 2.37081313083076 0.0181809352994258 -83.3416574381691 62.6283751348073 -1.33073319016782 0.183969157111053 CEP83 other 1 1 1 2.37081313083076 -1.33073319016782 0.570189782326106 -2.53529117997944 9.7104013997967 -0.261090255242438 0.794145622806948 -13.6588149340139 14.4336157291401 -0.946319701891335 0.344507311229943 SULT1B1 other 1 1 1 -0.261090255242438 -0.946319701891335 0.0667031472233169 859.660997022481 396.070193559387 2.17047637262708 0.030507366987589 1254.06340332 630.669382488876 1.98846406396163 0.0473822901767532 NUDT4 essential 1 1 1 2.17047637262708 1.98846406396163 0.004623581458899 114.720107038617 42.4263016401375 2.70398556093058 0.0071187225209127 -72.0793642805975 93.1521397493816 -0.773781090531268 0.439478641447079 SCAI other 1 1 1 2.70398556093058 -0.773781090531268 3.31366295913812e-62 40.4019316493321 13.0471038375503 3.09662068704115 0.00208313760187592 -128.791827637444 16.6747733818422 -7.7237528024033 7.7603394979877e-14 NMNAT1 other 3.21557853554763e-58 7.49726398900591e-10 1 3.09662068704115 -7.7237528024033 0.134643743700403 193.107443405653 99.9508950174982 1.93202315368808 0.0540042191887533 89.3617870964508 191.924117840797 0.465609992646039 0.641727180338498 SLC19A1 other 1 1 1 1.93202315368808 0.465609992646039 0.000614394907532119 -13.8886411601877 17.6847056569227 -0.785347600894388 0.432675365626312 -60.7035411677408 22.6064472100954 -2.68523136800692 0.00752378144445495 HSPB7 other 1 1 1 -0.785347600894388 -2.68523136800692 2.53366444449412e-18 377.072554334976 88.2304002103264 4.27372598827727 2.36044576769069e-05 -101.182711048769 113.296430378685 -0.893079426338265 0.372305055105668 UQCRH essential 2.12954496559731e-14 1 0.201936135425938 4.27372598827727 -0.893079426338265 2.92267414480145e-15 0.236176914734064 3.6562566868694 0.0645952773453349 0.948525715277242 -20.5623913483444 4.67439603293892 -4.39894078367516 1.36753450048102e-05 TAS1R1 other 2.35976710451269e-11 0.114954950110434 1 0.0645952773453349 -4.39894078367516 1.04247817577992e-10 304.527804258021 110.936177013368 2.74507209871965 0.00629919158549752 -631.867069166405 189.518562340136 -3.33406428037571 0.00092877386812153 PSMD1 essential 7.66951193921288e-07 1 1 2.74507209871965 -3.33406428037571 0.311951016892009 145.697386447233 308.924966301323 0.471627101530927 0.637428899383879 -571.470963706284 561.457392656456 -1.01783496162095 0.309320852778315 SUSD5 other 1 1 1 0.471627101530927 -1.01783496162095 0.244624327710577 -48.1320231350336 185.747952527167 -0.259125457267121 0.795660182078511 -571.406540874144 359.639187812285 -1.58883280865486 0.112819687981856 HEG1 other 1 1 1 -0.259125457267121 -1.58883280865486 0.0338659592915424 -168.996692699569 394.030536241465 -0.428892375478247 0.668212411216932 -2215.02874837051 856.008348016944 -2.5876251715324 0.00998501671963283 TOMM20 essential 1 1 1 -0.428892375478247 -2.5876251715324 1.64224278411099e-05 110.364445925998 106.949289778503 1.0319324808474 0.302673208666655 -747.007378502612 217.9115947066 -3.42802951586123 0.000665465115389523 AGFG1 other 0.089338007455638 1 1 1.0319324808474 -3.42802951586123 4.04984454755085e-08 489.746356464771 107.811681318719 4.54260939514483 7.19364413845477e-06 -601.226701430673 236.134725372659 -2.54611726624214 0.0112342973286609 STAT5B other 0.000266965752574552 1 0.0628508688376793 4.54260939514483 -2.54611726624214 5.21930296236975e-06 4.9855751133061 4.11393897772845 1.21187386110888 0.226218518289893 54.210741872826 10.8486604656775 4.99699866581091 8.45252841513236e-07 CD7 other 0.0298596322477174 0.00747457087750155 1 1.21187386110888 4.99699866581091 0.646952115087865 -1213.48744027007 2470.21837428063 -0.491247030183501 0.62349779617195 -4872.18928733214 5453.82282941632 -0.893353055228158 0.372158713163049 CNP other 1 1 1 -0.491247030183501 -0.893353055228158 0.0752895754917337 -54.8751917934343 61.49532840401 -0.892347324871852 0.372696772853057 244.509944032848 135.771245750657 1.80089637302061 0.0724069537371711 JUP other 1 1 1 -0.892347324871852 1.80089637302061 0.994352362665833 -14.8240103458843 202.786838686049 -0.0731014420952363 0.941758764500802 -41.8579778761693 447.718914993989 -0.0934916450352143 0.92555573683317 HAP1 other 1 1 1 -0.0731014420952363 -0.0934916450352143 0.0404655623427245 8.43579403308311 15.0210931631398 0.561596545701725 0.574678168532193 -40.0233561106757 24.1434518536294 -1.65773131171628 0.0980877053944458 CCDC13-AS1 other 1 1 1 0.561596545701725 -1.65773131171628 0.0015512269740455 955.919315242652 450.080168508352 2.12388676979646 0.0342394088442855 -2279.811925533 993.700607053913 -2.29426439850138 0.0222476972708896 EIF1 essential 1 1 1 2.12388676979646 -2.29426439850138 2.28676937033324e-12 204.0179268469 28.5973262917956 7.13416089200727 4.05953167901731e-12 -93.4647968772594 77.3026341680279 -1.20907648081048 0.227285718451678 ENDOV other 1.74846386055679e-08 1 3.89836827136033e-08 7.13416089200727 -1.20907648081048 0.0421260114279767 539.476412628865 226.286869403639 2.38403763351631 0.0175488083363316 754.249897131925 611.685543748064 1.23306804426063 0.21821174621175 RNF213 other 1 1 1 2.38403763351631 1.23306804426063 2.98206822896672e-13 36.3323465832375 31.3624387122597 1.15846688188298 0.247304803567904 -129.457813196034 40.4662293981156 -3.19915680609626 0.00147840276252873 PLK3 other 2.32362756401087e-09 1 1 1.15846688188298 -3.19915680609626 7.8471034726903e-17 269.542897834615 83.6254039669193 3.22321788653172 0.00136252272881702 -929.678849004502 177.124667149633 -5.24872601860203 2.39446733267371e-07 NET1 other 6.48720044087307e-13 0.00215214723860713 1 3.22321788653172 -5.24872601860203 0.174879113561982 -2.0840324582995 3.77389082884639 -0.552223832859666 0.581076673735035 15.0909828988234 8.98083660399945 1.6803537982311 0.0936014904710257 PHOSPHO1 other 1 1 1 -0.552223832859666 1.6803537982311 2.35021337237617e-11 287.044084929312 40.3259865459076 7.11809206707287 4.50694302606551e-12 234.143480088745 113.329022151333 2.06605047536794 0.0394111566107832 CBX2 other 1.755609389165e-07 1 4.32621461072028e-08 7.11809206707287 2.06605047536794 0.0627060702429759 46.9182879377436 23.1403137578117 2.02755625653109 0.0432119053806799 82.1747435443937 52.255037532115 1.57257074964094 0.116541942648274 HOXB2 other 1 1 1 2.02755625653109 1.57257074964094 0.309037709427271 38.2207529973528 269.218667926442 0.141969178035588 0.887169628925207 1159.53400578756 756.591245356262 1.53257655689839 0.12610216518264 C1QTNF1 other 1 1 1 0.141969178035588 1.53257655689839 0.28853903601532 26.618909366321 53.0570205068319 0.501703810580418 0.616128543891836 -131.823150719517 112.28888553865 -1.17396436955591 0.241048682947323 MARCH3 other 1 1 1 0.501703810580418 -1.17396436955591 1.07728150791934e-07 362.297215086132 135.527661925179 2.67323445221202 0.00779300560205017 -83.4296871853328 174.030722711092 -0.479396315119797 0.631895983540964 PIFO other 0.000692153368838175 1 1 2.67323445221202 -0.479396315119797 1.17285670787885e-05 92.0792261910323 37.8313082574703 2.43394242579095 0.0153341445537485 -146.122396733595 67.205508082997 -2.17426221304864 0.0302201230763718 XXYLT1 other 0.0647299617078335 1 1 2.43394242579095 -2.17426221304864 0.783165485941585 -3.36074477975065 4.81088899461109 -0.698570427111327 0.485192965203706 -3.00338895885119 5.71661357688915 -0.525379041010074 0.599586793015773 LRRC63 other 1 1 1 -0.698570427111327 -0.525379041010074 1.70668032720889e-05 69.9697296811058 15.5245362101637 4.50704154596886 8.45189006214507e-06 -20.6349390545585 36.4244254111917 -0.566513783583756 0.571335393920951 TCAP other 0.092723942177259 1 0.0736328662214079 4.50704154596886 -0.566513783583756 0.352653777802579 -46.4830124575318 34.2131574072882 -1.35862971967708 0.174969665864958 -68.541557929982 58.1744348091799 -1.17820754348208 0.239359486938076 NRROS other 1 1 1 -1.35862971967708 -1.17820754348208 0.00719029362484141 10.8753114382789 19.9373303838734 0.545474806751237 0.585707232777948 -76.3088778374117 33.900493686638 -2.25096656534796 0.0248873589713255 CEP19 other 1 1 1 0.545474806751237 -2.25096656534796 7.52295782336632e-16 144.349150622878 38.8931371468667 3.71142986172065 0.000232903767658197 -288.232704712196 66.1320510276232 -4.35844193901988 1.63717042249298e-05 FBXO45 other 6.12669685134953e-12 0.137063907771112 1 3.71142986172065 -4.35844193901988 1.59088023252632e-52 484.379006136325 91.8435160424954 5.27395974161318 2.10242991310527e-07 -556.829302593002 118.503564821709 -4.69884010182111 3.50860690850399e-06 GNG5 other 1.52549505496949e-48 0.0303073464756575 0.00191342146391711 5.27395974161318 -4.69884010182111 0.00142224975120926 25.2000129863685 25.1910325684713 1.00035649264765 0.317690342900255 -42.9902182091795 30.1528059912486 -1.42574519338786 0.154654181794961 SLC25A30 other 1 1 1 1.00035649264765 -1.42574519338786 0.0123530140734917 159.197151066478 60.8592935577808 2.61582318426575 0.00921011686977228 27.1475630262591 99.0638726662417 0.274041002997354 0.784182894491955 MSRB3 other 1 1 1 2.61582318426575 0.274041002997354 1.43864791034887e-09 77.2473536926632 51.4146883191716 1.50243745937207 0.133708074675253 -371.665166078595 83.690392035018 -4.44095381848709 1.13653831163179e-05 LEMD3 other 1.01741180219872e-05 0.0959579296510721 1 1.50243745937207 -4.44095381848709 0.0701059383744922 20.0532706121658 20.0468657672497 1.00031949358022 0.317709484949765 -37.8102964037437 32.5196386256247 -1.16269116145559 0.245589363645274 TLR10 other 1 1 1 1.00031949358022 -1.16269116145559 0.0451526649411126 26.2289746360683 34.8668506236356 0.752261077984719 0.452299063058092 -87.5377049369809 56.5603319470835 -1.54768725577635 0.122421470582754 TLR1 other 1 1 1 0.752261077984719 -1.54768725577635 0.0541747059154297 9.71845400800921 19.2360189400071 0.505221690533728 0.61365783739401 -52.3068636912643 31.2042985565681 -1.67627109439556 0.0944003119726992 TLR6 other 1 1 1 0.505221690533728 -1.67627109439556 0.0593878260996163 7.10311681281523 3.26528599006865 2.17534293609176 0.0301410097426511 2.59818052340172 5.07624556210059 0.51183113417519 0.609028334219477 FAM53A other 1 1 1 2.17534293609176 0.51183113417519 0.630873977828699 -16.9648464814706 17.8273781664173 -0.9516175807292 0.341816984149574 -18.5540825584693 28.919228688674 -0.641582898292716 0.521480404688392 NWD2 other 1 1 1 -0.9516175807292 -0.641582898292716 1.24996295725686e-58 75.1173713601924 20.3189153288401 3.69691837110876 0.000245923199594218 -203.323591720959 27.0238077954943 -7.52386907350856 3.04677814368884e-13 CYB561D1 other 1.20771420930158e-54 2.93587541925856e-09 1 3.69691837110876 -7.52386907350856 0.000379452064861922 54.2175874231224 35.2440470934154 1.53834737762712 0.124685777856232 -185.011928182768 70.6683911614959 -2.61802943496997 0.00915029903588427 TRMT10C other 1 1 1 1.53834737762712 -2.61802943496997 2.95406898316917e-11 210.263501187485 30.7466979827846 6.83857178111335 2.69918498846303e-11 55.3201390562088 65.3312490720597 0.846763835713462 0.397589177812572 CTU2 essential 2.20284924074925e-07 1 2.57664198998681e-07 6.83857178111335 0.846763835713462 5.3527557607283e-05 218.480247125906 88.4145748155937 2.47108859123725 0.013851498326682 -170.896627816214 133.669521679836 -1.27850107989123 0.20175294360005 MGA other 0.274328732737325 1 1 2.47108859123725 -1.27850107989123 7.10672682579106e-09 21.5069491890273 12.1515222655818 1.76989752550953 0.0774430629079782 -79.0870528263149 19.7796718306583 -3.99840065615906 7.48891056966561e-05 C12orf66 other 4.88800671077909e-05 0.601284629638452 1 1.76989752550953 -3.99840065615906 9.19633822845367e-09 74.9414970040777 58.7277657899046 1.27608288849565 0.202613451979491 -376.866327518862 91.3303449617235 -4.12640867256996 4.42400887247955e-05 PIGG other 6.28937571443947e-05 0.361485764970304 1 1.27608288849565 -4.12640867256996 0.00089240890554628 506.591901404048 449.790574695829 1.12628394169138 0.260663467436467 -1271.31101188612 345.4650118494 -3.67999932925286 0.000262368424128146 PRPF8 essential 1 1 1 1.12628394169138 -3.67999932925286 6.73092439813659e-08 -20.1087296166546 98.4379554720733 -0.204278212811515 0.838230978749428 -718.289109617263 150.302417423109 -4.7789591274187 2.40903116647627e-06 ADCY6 other 0.000438183178318692 0.0209537530860106 1 -0.204278212811515 -4.7789591274187 0.111751496726719 -134.192594289839 144.480584200293 -0.92879327026951 0.353511321829064 -187.920317447092 102.700457012612 -1.82979046942328 0.0679654914918699 PITPNA other 1 1 1 -0.92879327026951 -1.82979046942328 1.38113937395014e-08 149.479394742151 175.716470948266 0.850685163066814 0.395409067492494 -1159.6704679632 268.297022606027 -4.32233819331676 1.91266299146855e-05 DDX23 essential 9.3765552097475e-05 0.159573473378221 1 0.850685163066814 -4.32233819331676 0.0533372129346179 116.484782066965 126.09027302 0.92382052379638 0.356088413796909 -214.733994834851 94.2526532349585 -2.2782806368278 0.0231906629442462 ZBTB4 other 1 1 1 0.92382052379638 -2.2782806368278 0.0422250539226254 -10.6093063295728 5.41461967318977 -1.95938163156764 0.0507019876111489 6.72400434959902 4.04743568423704 1.66129986346319 0.0973687962994309 TNK1 other 1 1 1 -1.95938163156764 1.66129986346319 4.90955271780163e-05 -5.88514906438312 5.20076847251558 -1.13159220516819 0.258425081158201 -16.7868696479543 3.88758161636753 -4.31807516973485 1.94842742490303e-05 SLC16A11 other 0.252596487330894 0.162420910139916 1 -1.13159220516819 -4.31807516973485 0.00016785989012721 0.263581169860927 2.93861148469268 0.0896958210481138 0.928569937101415 -9.24949028136467 2.19661614353927 -4.21079045083478 3.09020906762948e-05 SLC16A13 other 0.808581090742772 0.255096758532813 1 0.0896958210481138 -4.21079045083478 0.000352243461220194 28.0705762679869 18.5815753787314 1.51066719025969 0.131594342641214 -17.1317310061928 23.8593658627936 -0.718029603331078 0.473121838971486 GLIS1 other 1 1 1 1.51066719025969 -0.718029603331078 0.797437011132761 -1.80940594059368 42.4694280248512 -0.0426049048632089 0.966035944814179 -39.4583116206355 68.2653229043914 -0.578013989268002 0.563552396210896 CHRNA9 other 1 1 1 -0.0426049048632089 -0.578013989268002 3.62360927138123e-05 592.300693702845 133.646632389192 4.43184151455464 1.18224381168418e-05 747.075417681121 171.606757420248 4.35341491740681 1.67026930635436e-05 PODN other 0.189768417542235 0.139734730169605 0.102453248720551 4.43184151455464 4.35341491740681 0.00509982662667487 65.8478396036473 20.2296297624848 3.25501951230763 0.00122239999573507 27.6797205005726 42.390067137932 0.652976566668467 0.514116335587779 EXO1 other 1 1 1 3.25501951230763 0.652976566668467 7.8483163151982e-15 1.25424386458242 61.6407036318702 0.020347656510753 0.983775347600711 -489.668517799981 82.5498861079703 -5.93178913850377 6.10840045721375e-09 RALGAPA1 other 6.29356485315744e-11 5.65943302360854e-05 1 0.020347656510753 -5.93178913850377 1.97584224973029e-10 113.164680630598 28.3505265045445 3.99162536231764 7.69559890334689e-05 -71.2209310931821 40.0384950652895 -1.77881139081388 0.0759657541349239 LIG4 other 1.44117933695327e-06 1 0.643505980297867 3.99162536231764 -1.77881139081388 2.42694457610787e-08 -478.158957911323 695.920127431478 -0.687088846928635 0.492390367787887 -6167.78726495199 1164.0817442908 -5.29841421807507 1.85430443112083e-07 ATP2A2 essential 0.000162289783804334 0.00167054286199676 1 -0.687088846928635 -5.29841421807507 0.0004107597568471 112.345514751592 34.4272920115882 3.26326899930951 0.00118779111635543 -3.71091745166374 60.7823644798033 -0.0610525352776757 0.951345281492478 ZWILCH other 1 1 1 3.26326899930951 -0.0610525352776757 0.0150272495526633 3256.37438435416 2066.27060826305 1.57596704484489 0.115757016672558 -4165.39904206325 3648.05960291837 -1.14181222223755 0.254157336740216 RPL4 essential 1 1 1 1.57596704484489 -1.14181222223755 5.15662367864658e-10 31.7768493281662 37.3385806404312 0.851045990049162 0.395209889721956 -331.303427692509 65.9223274627958 -5.02566338968363 7.32983721840128e-07 SNAPC5 essential 3.71637868520059e-06 0.00649496875922538 1 0.851045990049162 -5.02566338968363 0.875773477098498 -4.85030576974191 20.8436173184657 -0.23269980904154 0.816104215726129 -18.3079598091212 35.9260059304279 -0.509601870148752 0.610589436281468 GOLGA6L2 other 1 1 1 -0.23269980904154 -0.509601870148752 1.35699838711937e-07 78.1455660589697 72.5633982135097 1.0769281481145 0.282105155890982 -481.979671802423 121.378479849136 -3.97088242002606 8.36879056390545e-05 C12orf76 other 0.000867121969369277 0.669921684640632 1 1.0769281481145 -3.97088242002606 0.624439421956399 -11.0030914470945 12.2367758160317 -0.899182236605091 0.369051925765027 -15.0381611996168 16.6368790658855 -0.903905181979294 0.366544831850871 GALNTL6 other 1 1 1 -0.899182236605091 -0.903905181979294 0.703914898479621 -1.80438166280004 14.3978686540053 -0.125322831188496 0.900327657453539 -11.4667319282516 16.3466324543113 -0.701473649713541 0.483394125701475 LINGO2 other 1 1 1 -0.125322831188496 -0.701473649713541 6.31817864704522e-06 19.1926219939278 54.0981284284672 0.354774232519074 0.722930666923109 -356.656525799676 92.9728148065691 -3.83613776286868 0.000143477406419887 DENND4A other 0.0358240729287464 1 1 0.354774232519074 -3.83613776286868 0.102682489988875 -54.0889563390155 48.9579890338539 -1.10480347347628 0.269855461717437 -179.514440812516 84.1389929739481 -2.1335463435853 0.0334388148839028 IGDCC3 other 1 1 1 -1.10480347347628 -2.1335463435853 1.49722283910973e-06 -80.4045197943517 46.6605011172945 -1.72318166048478 0.0855663073891341 89.1559735359553 64.2382240580586 1.38789598939373 0.165879171198149 TTC9B other 0.00894291201800243 1 1 -1.72318166048478 1.38789598939373 0.0346452151930055 1.9626793921771 3.41323300135081 0.575020630411214 0.565572593355372 -15.7734382328112 7.45448648669554 -2.11596576919993 0.0349113841100303 IL20RB other 1 1 1 0.575020630411214 -2.11596576919993 7.78376363666748e-51 133.645037746851 100.049494926826 1.33578922956678 0.182311835179791 -1050.2637446348 128.473299558638 -8.17495735100535 3.21996966308821e-15 AKIRIN1 other 7.44049966029044e-47 3.12787853072389e-11 1 1.33578922956678 -8.17495735100535 6.33216605994393e-05 83.6882882594376 48.3200176094256 1.73195897683433 0.0839849027481305 -307.685059164494 101.87184868805 -3.02031486742408 0.002672866982638 MSL2 other 0.321737357505751 1 1 1.73195897683433 -3.02031486742408 1.47918681439902e-53 70.2170114369587 14.5615831134676 4.82207263384823 1.96629799808669e-06 -67.5609855722631 18.1797811264534 -3.71627057016408 0.000228498178155873 ZNF497 other 1.42075893523026e-49 1 0.0175000521829715 4.82207263384823 -3.71627057016408 0.000229469327591445 35.8759476090355 20.3191568781904 1.76562186236886 0.0781575800647891 -48.6540421673964 28.3277990506149 -1.71753697067899 0.0865895501302814 TRAM1L1 other 1 1 1 1.76562186236886 -1.71753697067899 0.710104618364944 -69.5829696786333 104.785451417069 -0.664051819576342 0.50700734714058 3.53132643799506 175.288009081386 0.0201458528538337 0.983936217184223 CMKLR1 other 1 1 1 -0.664051819576342 0.0201458528538337 0.344288608619317 -205.234957054222 433.594967065419 -0.473333347117142 0.636212269804723 -831.168727362324 607.985854000001 -1.36708563512454 0.172302878509913 UGT8 other 1 1 1 -0.473333347117142 -1.36708563512454 0.477415080181385 -14.7872005973315 16.5948496815835 -0.891071680736099 0.373381048975523 -38.3986746703867 33.9049475967624 -1.13253897711535 0.258028922712002 KY other 1 1 1 -0.891071680736099 -1.13253897711535 0.822611530284388 18.0515860885423 44.0791544021487 0.409526596718523 0.682354370075968 -24.3471482583859 92.9349117382204 -0.261980646486942 0.79346008785372 SLCO2A1 other 1 1 1 0.409526596718523 -0.261980646486942 1.52529156130323e-07 285.858988333128 136.900688566265 2.08807560668156 0.0373681016976064 -235.630528292223 157.915792573608 -1.49212769952942 0.136385564797975 BRSK2 other 0.000972678428643072 1 1 2.08807560668156 -1.49212769952942 0.315836383396338 89.0547587212852 201.157915208339 0.442710686422911 0.658194060823574 -382.012003160325 369.130798443568 -1.03489604435899 0.301289805499502 SH3PXD2B other 1 1 1 0.442710686422911 -1.03489604435899 1.50428385722926e-12 132.427451245154 60.8485014463133 2.17634696167489 0.0300641681617327 -354.010379815204 84.8314785812966 -4.17310160963356 3.62692753820846e-05 LARP7 other 1.15363529010912e-08 0.298097174365353 1 2.17634696167489 -4.17310160963356 4.71961814649238e-05 -277.665694541922 218.802382966129 -1.26902500227754 0.20510609108803 -922.04170768185 264.211828701258 -3.4897820896747 0.000532386050233074 FGFBP3 other 0.243626688721936 1 1 -1.26902500227754 -3.4897820896747 0.000977244105528906 77.4259112598284 135.397544025167 0.571841327088155 0.567724167996308 -854.315926505232 276.32729393107 -3.09168129702866 0.00211794037874414 NR1D2 other 1 1 1 0.571841327088155 -3.09168129702866 1.29755359190837e-06 2094.68937968998 1161.36311657135 1.80364723986935 0.0719767684987326 -8753.64501950219 2370.17834838913 -3.69324317954872 0.000249529953997212 RPL15 essential 0.00778661910504215 1 1 1.80364723986935 -3.69324317954872 6.5154915986984e-10 447.135905521993 92.0559811761322 4.85721731287053 1.66011558654564e-06 124.259578261948 106.841967001664 1.16302218827563 0.245453730786499 HRAS og 4.67356212374636e-06 1 0.014804910800814 4.85721731287053 1.16302218827563 6.19636627136953e-12 684.657109169837 105.33189563524 6.49999798295452 2.24445933698018e-10 76.7002116940868 191.362567689577 0.400810945526755 0.688759795893597 SRP72 essential 4.6900296307996e-08 1 2.1290941270594e-06 6.49999798295452 0.400810945526755 2.02430483024317e-10 11.5847458732279 17.1063195585545 0.67722024212009 0.498623751827731 -108.070433555636 24.1986500430755 -4.46596952157506 1.01555462807987e-05 THAP6 other 1.47571822124727e-06 0.0860174769983653 1 0.67722024212009 -4.46596952157506 2.55970155278505e-07 112.534747679587 20.8229816018305 5.40435322046746 1.08733517254473e-07 57.7639185710946 36.7854542743597 1.57029238079459 0.117093031011136 CEP135 other 0.00161133212747819 1 0.000994368015292152 5.40435322046746 1.57029238079459 0.271250173636112 -8.01660422113729 14.6450270107851 -0.547394293997109 0.584387318659926 -30.9730963098731 20.8617728245328 -1.4846818901915 0.138349058039902 BTC other 1 1 1 -0.547394293997109 -1.4846818901915 1.30898020199425e-08 143.082004154784 33.9992234204915 4.20839036189714 3.12461882504144e-05 -87.9689330187913 56.0890580919878 -1.56837957368654 0.117518011068059 DENND6A other 8.89713843295494e-05 1 0.265936308199277 4.20839036189714 -1.56837957368654 1.58231749855757e-09 40.1981268265199 42.1455112983779 0.953793787004479 0.340716521044872 -344.594040115958 69.5281184012723 -4.95618244876382 1.03093738204031e-06 PDE12 other 1.11759084923121e-05 0.00908358927315714 1 0.953793787004479 -4.95618244876382 2.06646558955445e-35 39.2063322205815 9.69057523292455 4.04582094232906 6.16283991254288e-05 -46.5159936086737 12.5028352676216 -3.72043561424307 0.000224753432529515 GLMN essential 1.90548792012816e-31 1 0.517678552653602 4.04582094232906 -3.72043561424307 0.994300188120739 -0.890661126955653 11.4689467810262 -0.077658493317724 0.9381353372098 -1.95857735838728 18.9205033979447 -0.10351613364579 0.917600942302391 DNAH12 other 1 1 1 -0.077658493317724 -0.10351613364579 1.28722568177694e-15 10.0402335616997 2.7699873787156 3.62464957019235 0.000323329586559619 -4.0768764181347 3.57385346659346 -1.14075086072869 0.254596963358414 AMY1B other 1.04548469873923e-11 1 1 3.62464957019235 -1.14075086072869 0.000541431745643536 109.122875801556 36.9740847287465 2.95133406552497 0.00333511758543382 -98.4260442376495 80.7553887226988 -1.21881704483683 0.22357418447222 RSRC1 other 1 1 1 2.95133406552497 -1.21881704483683 6.17689933425985e-24 518.574751380646 88.7764131531769 5.84135732636421 1.01080996209821e-08 -89.6019317563352 103.017708790301 -0.869772127612789 0.384901338214414 PTDSS2 other 5.43567141414867e-20 1 9.40962993717227e-05 5.84135732636421 -0.869772127612789 0.245091051270414 -10.5051419169067 6.96105049945331 -1.50913169179447 0.131987775814014 -19.2473879062115 15.2031637742553 -1.26601200855341 0.206183263476184 P2RY14 other 1 1 1 -1.50913169179447 -1.26601200855341 0.01552434099442 -57.1038753283777 37.8770403966666 -1.50761186012314 0.132374805767763 -388.211452998578 141.044841786035 -2.75239738002964 0.00616180182325028 AMZ1 other 1 1 1 -1.50761186012314 -2.75239738002964 0.0574000032923357 -0.815321533801791 5.1527000964777 -0.158231901437293 0.87434699167985 6.05989326849764 6.2844692762812 0.964264920725899 0.335445193971325 FUT1 other 1 1 1 -0.158231901437293 0.964264920725899 0.0663408948417697 61.543302818598 26.451922123963 2.32660985958542 0.020442381593157 64.0712478920741 55.2119695814829 1.16045937824255 0.246495384403107 ZIC4 other 1 1 1 2.32660985958542 1.16045937824255 0.000211856444383692 54.4595747052754 41.7277295130118 1.30511713291981 0.192541312753052 -241.738809459666 82.0126031433333 -2.94758122769472 0.00337465290064184 FBXW8 other 1 1 1 1.30511713291981 -2.94758122769472 1.43903372075615e-57 318.691252346468 123.669414598623 2.57696095175027 0.0102950363005829 -1074.13527413625 143.610969893303 -7.479479283054 4.14312231633227e-13 CTBP2 other 1.38909925064591e-53 3.99065541509124e-09 1 2.57696095175027 -7.479479283054 0.43132169222092 -184.60590000938 152.423542933594 -1.21113770521531 0.226495692188256 -299.951364787543 332.892375235754 -0.901046065038643 0.368058998813499 CHST2 other 1 1 1 -1.21113770521531 -0.901046065038643 2.25747366764598e-06 50.1759192165682 103.934107087127 0.482766635734949 0.629502638168328 -393.014725337485 136.52533501185 -2.87869445845616 0.00418878027423813 ZDHHC14 other 0.0133168371654436 1 1 0.482766635734949 -2.87869445845616 0.0304018822849355 62.5214332614209 36.0224804817132 1.73562265633428 0.0833338691166151 -92.4604633711657 78.6729455217129 -1.17525106957699 0.240532755697084 ATR ts 1 1 1 1.73562265633428 -1.17525106957699 0.0804307140127256 1631.71136613154 808.972299746865 2.01701759954219 0.0443046910123219 -673.179369250413 600.747345778382 -1.12056986016007 0.263086437398417 LRRC75A-AS1 other 1 1 1 2.01701759954219 -1.12056986016007 0.0135615599025194 -21.814381859112 39.2192949768741 -0.556215553389599 0.578347542481132 -246.935500891098 85.6547749031874 -2.88291576471014 0.00413410230510324 GK5 other 1 1 1 -0.556215553389599 -2.88291576471014 0.289537757776544 -3.0253808939273 4.11584844469284 -0.735056437228238 0.462699403425338 -16.2677810672249 10.386628841933 -1.56622339305592 0.118020136834771 RTP1 other 1 1 1 -0.735056437228238 -1.56622339305592 1.00153802095433e-44 110.328921729955 22.0955875482444 4.99325584753329 8.58787049315176e-07 -111.115449579561 28.3693897171097 -3.91673739504331 0.000104084300587848 PDIK1L other 9.4615296839556e-41 0.826845683869861 0.00771791921219549 4.99325584753329 -3.91673739504331 0.0964554264376638 70.5430775724609 52.4133529725164 1.34589896604117 0.179031319784838 -119.463207016227 114.470541947004 -1.04361528288679 0.297239065257054 SPSB4 other 1 1 1 1.34589896604117 -1.04361528288679 0.000237991180422669 1.16850062486662 0.963203442334925 1.21314000086423 0.225734642704693 -2.71336323626996 1.21017884718177 -2.24211755360687 0.0254569798451738 RAG2 other 1 1 1 1.21314000086423 -2.24211755360687 1.26157740666454e-05 17.1955985003195 23.057589473083 0.745767397775612 0.456210730127746 -91.6802359252607 28.969795809371 -3.16468353897077 0.00166150860876186 TRAF6 other 0.0694498362368828 1 1 0.745767397775612 -3.16468353897077 0.079160146151949 4.78878456246076 26.9676669242687 0.177575041100469 0.859140345320723 -88.3059056648135 45.882589441683 -1.9246059723166 0.0549381535547635 ZNF654 other 1 1 1 0.177575041100469 -1.9246059723166 0.0845995862119966 6.74043879163376 6.43895270282827 1.0468222244703 0.295758906982057 -9.68906451411704 4.77903336039228 -2.02741093929542 0.0432254307441371 TVP23C other 1 1 1 1.0468222244703 -2.02741093929542 5.07288932083663e-10 613.535261393872 1134.06840370048 0.541003751971131 0.588781289937325 -4551.80379176029 1457.46719674103 -3.12309175941548 0.00190886789559726 MARCKSL1 other 3.65755320032321e-06 1 1 0.541003751971131 -3.12309175941548 1.02357223874713e-08 135.904410409338 62.2599887353846 2.18285311593862 0.0295868300013809 -517.471992036933 121.283183621997 -4.26664255161489 2.44252252483247e-05 SH3BP5L other 6.98178624049421e-05 0.20265609388535 1 2.18285311593862 -4.26664255161489 6.33521136820232e-07 -36.5864016569754 104.541953703206 -0.349968604574235 0.726530480421719 345.378411535091 133.580749346678 2.58554030595188 0.0100446733516295 TMEM51-AS1 other 0.00389742203371807 1 1 -0.349968604574235 2.58554030595188 0.0139851217210329 -641.513458666771 675.470178808037 -0.949728764930545 0.342782324102679 -3340.51908718459 1149.19509288202 -2.90683375509987 0.0038394314045289 CADM2 other 1 1 1 -0.949728764930545 -2.90683375509987 0.804150167176526 2.17794130386658 4.91636196183448 0.44299856698385 0.657985481103554 6.38329114167728 10.1439383525299 0.629271484096243 0.529499403971297 ABO other 1 1 1 0.44299856698385 0.629271484096243 6.83285741612583e-05 1565.68442622951 366.295318112223 4.27437739116782 2.35383247761714e-05 931.704215456682 596.272820874465 1.56254684573798 0.118881418342274 CSRP2 other 0.345674256681806 1 0.201393906784922 4.27437739116782 1.56254684573798 0.000522876573113053 345.341337946415 97.8050606865197 3.53091481690592 0.000459637185513857 81.972901918825 168.187962147308 0.487388638712614 0.626235429066176 DDIT3 og 1 1 1 3.53091481690592 0.487388638712614 2.62694462050541e-18 125.752121557518 42.496287372104 2.95913194619598 0.0032527321948765 -256.909454221709 56.2545134867678 -4.56691273815993 6.44573363345197e-06 PCCA other 2.20768425907275e-14 0.0550723481642136 1 2.95913194619598 -4.56691273815993 3.38812430676707e-15 795.418451638417 146.003831004463 5.44792863424317 8.67619135832545e-08 -629.379461161633 251.084650359703 -2.50664252179489 0.0125634721493675 DCTN2 essential 2.73353869069967e-11 1 0.000794912652249778 5.44792863424317 -2.50664252179489 1.93883064458462e-06 118.43200307169 123.407400700697 0.959683150274965 0.337744159151795 555.33310427294 157.677846079851 3.52194755369571 0.000473357791947542 NPPA other 0.011491449230453 1 1 0.959683150274965 3.52194755369571 4.74735828743181e-16 169.422845206749 27.6936114335853 6.11775916669658 2.11723121716262e-09 -61.6481156800454 35.8597085818691 -1.71914714642202 0.0862989809388076 ZNF408 other 3.88286434329048e-12 1 1.98998562101115e-05 6.11775916669658 -1.71914714642202 0.0016241075292709 748.70747085415 278.814701232404 2.68532278801923 0.007533706854654 -263.319916990519 473.11889737193 -0.556561825057512 0.578123966694491 CTDSP2 other 1 1 1 2.68532278801923 -0.556561825057512 3.87636649110552e-09 1160.87013779181 288.934018351051 4.01776898551756 6.92215782100847e-05 -687.59895120239 370.007211878282 -1.85833932185241 0.0637961339529419 CKAP5 essential 2.69446234796745e-05 1 0.58014604697872 4.01776898551756 -1.85833932185241 5.40399960417744e-08 498.770353890006 190.53109866601 2.61778973292083 0.00915875661489483 -712.573107140376 246.713567507505 -2.88826072412374 0.00406714278754676 ARHGAP1 other 0.000353421574113205 1 1 2.61778973292083 -2.88826072412374 1.10993797001421e-14 601.15011952191 75.4680438620239 7.96562476988241 1.44537358348609e-14 -143.395204636002 221.663399610208 -0.646905194489305 0.518033717806472 MED16 other 8.87395407026361e-11 1 1.40027792768132e-10 7.96562476988241 -0.646905194489305 3.45689533303389e-13 787.219449894042 187.548558053448 4.19741670138406 3.27508631037228e-05 -751.220645447979 242.851556319237 -3.09333263839772 0.00210674164675915 ATG13 other 2.68981025863367e-09 1 0.278382336381644 4.19741670138406 -3.09333263839772 0.0014630693981842 -399.771323984989 204.700734657903 -1.95295500357187 0.051470221018524 -988.755746099113 271.644327301477 -3.63989101455364 0.000305780478265627 CHST1 other 1 1 1 -1.95295500357187 -3.63989101455364 0.159727941849316 -398.99064935514 380.353458645775 -1.04899966146153 0.294758064732929 -1167.72391097604 609.593772902581 -1.91557716447122 0.0560712290698894 GOLGA8A other 1 1 1 -1.04899966146153 -1.91557716447122 0.456119991096952 -128.358982015297 104.392403582989 -1.22958163247248 0.219527729196644 -65.6480694581632 138.580469402846 -0.473718048012434 0.635941964299343 TP53I11 other 1 1 1 -1.22958163247248 -0.473718048012434 1.52843807337579e-39 46.6865788475883 13.7767000263641 3.38880709881506 0.000765472388812134 -83.6523772830601 17.6036790379904 -4.75198264536238 2.73576763202707e-06 CENPS other 1.42572703484494e-35 0.0237300484402028 1 3.38880709881506 -4.75198264536238 1.81655562876744e-07 127.440840763737 29.839408866144 4.27089026245196 2.39053304159804e-05 -126.926474020821 65.9532744263442 -1.92449086303623 0.0549420391732571 DOLK essential 0.00115357208810264 1 0.204486196378297 4.27089026245196 -1.92449086303623 0.086870044745507 -161.144822837412 87.2158047424441 -1.84765620535506 0.0653277016381858 -349.440642360308 192.770839740706 -1.81272563231211 0.0705601874517184 PHYHD1 other 1 1 1 -1.84765620535506 -1.81272563231211 0.065914115552759 117.688549341709 62.2521196688564 1.89051473215274 0.0593489798388087 -38.6925525857163 119.384872543682 -0.324099291319836 0.746017573323777 PHYKPL other 1 1 1 1.89051473215274 -0.324099291319836 4.03860852651407e-06 69.632979801524 28.7109322827119 2.42531239027209 0.0157012944500205 -80.0150592078084 45.0394472534203 -1.7765550886447 0.0763402949188846 ZNF519 other 0.0233431572832513 1 1 2.42531239027209 -1.7765550886447 2.69395517949099e-30 463.920329670324 126.071970803131 3.67980548503335 0.000262561896728906 -862.874421033518 152.688559842156 -5.65120544673107 2.87805985015414e-08 TMEM9B other 2.44045399710089e-26 0.000264090771850144 1 3.67980548503335 -5.65120544673107 0.334779286051286 -121.800824175827 82.7856638374638 -1.47127918687665 0.141935340941654 -118.865895468172 100.263553479766 -1.18553443741807 0.236450451416198 NRIP3 other 1 1 1 -1.47127918687665 -1.18553443741807 0.000170038942515926 48.7932618474088 25.6033397963571 1.90573816679773 0.0573431042395556 -64.1677639015571 40.1645011354713 -1.59762382421046 0.110852835704321 PTPN2 other 0.818227391386638 1 1 1.90573816679773 -1.59762382421046 0.000134243574128917 788.730769230771 204.375084823521 3.85923151988827 0.000130899445080658 383.394650803745 247.523197825246 1.54892411770805 0.122123830650096 SCUBE2 other 0.654571667452599 1 1 3.85923151988827 1.54892411770805 3.59351480631043e-16 187.885201668825 82.4885066355056 2.27771370015266 0.023224739540385 -639.389289589587 129.368649750717 -4.94238202857988 1.10077523821603e-06 SMAD2 ts 2.9438073293295e-12 0.00968792287153924 1 2.27771370015266 -4.94238202857988 4.37401948184034e-21 1036.78476401646 179.507000362928 5.7757344388814 1.45436164268717e-08 -342.471275952432 217.202088762862 -1.57674025099426 0.115577251707577 EIF3F essential 3.78002763620642e-17 1 0.000134964760441369 5.7757344388814 -1.57674025099426 7.23999268140567e-33 106.187554600552 48.9290294251143 2.17023627585076 0.0305434241217674 -834.127309567948 89.5527716949509 -9.31436619750069 6.73219004154471e-19 ZNF25 other 6.62604130202247e-29 6.59619980270551e-15 1 2.17023627585076 -9.31436619750069 0.0112971092755945 131.934133402585 115.197397820006 1.14528744484948 0.25271550122072 -444.174914675767 226.595327720787 -1.96021215063659 0.050604542173382 ARL10 other 1 1 1 1.14528744484948 -1.96021215063659 0.00107249681364584 22.8647054459124 164.313062037325 0.139153303836055 0.889392965988274 -1052.20221843004 323.206711659658 -3.25550856610312 0.00121972802803123 CLTB other 1 1 1 0.139153303836055 -3.25550856610312 0.00252965897611946 312.377124645895 120.067578088681 2.60167756873696 0.00959111369646598 -192.282324969649 232.470967668329 -0.827124035737577 0.408617144004312 CCDC14 other 1 1 1 2.60167756873696 -0.827124035737577 1.21580922702935e-59 41.8109893607117 47.0334482240395 0.888962875134074 0.374513219521358 -461.429146387635 53.2760727717291 -8.66109535447012 9.17499685295635e-17 PPP2R2D other 1.1762954271509e-55 8.95204442942951e-13 1 0.888962875134074 -8.66109535447012 0.0153705795219111 -48.6082635767595 42.084606778365 -1.15501289658594 0.248764472309826 -190.149684549091 66.4017831073219 -2.86362316869957 0.00440546216564417 ALG10B other 1 1 1 -1.15501289658594 -2.86362316869957 2.65181303678192e-11 46.2430711511533 7.40104686238705 6.24817975226799 9.86787048223081e-10 -15.4342466115354 16.1394603310888 -0.956304999976054 0.339446887932541 LINC00476 other 1.97931325065403e-07 1 9.30441507769543e-06 6.24817975226799 -0.956304999976054 1.27955816387027e-07 -353.13378328274 218.764213667752 -1.61422097957513 0.10719964168622 -876.50458005877 162.368248910874 -5.39825111090465 1.10503852938662e-07 TOM1L2 other 0.000818917224876972 0.00100182793074191 1 -1.61422097957513 -5.39825111090465 0.0630132198330074 -0.0256559263185294 19.5094772353425 -0.00131504939927618 0.998951348322116 36.7419037525834 23.6850948993034 1.55126690050391 0.121568301059985 TEX26 other 1 1 1 -0.00131504939927618 1.55126690050391 0.0147756518887212 30.4948001395694 11.1660558735423 2.73102700585855 0.00656863605958067 47.6118978244417 22.1780571522065 2.14680201686219 0.0323575192015433 GPR156 other 1 1 1 2.73102700585855 2.14680201686219 4.04298411584301e-09 138.865032459619 21.9535574451823 6.32540000892167 6.34263129336536e-10 35.3169536968848 57.004390503704 0.619547957355846 0.53588356943884 B3GNTL1 other 2.8070438716298e-05 1 5.99061525658358e-06 6.32540000892167 0.619547957355846 1.76923434564317e-05 463.100578034686 97.8081336663575 4.73478595976907 2.96589455431347e-06 353.353121387285 194.960717409489 1.81243240219061 0.0706039643292572 MLXIP other 0.0958881841091814 1 0.0262600303838915 4.73478595976907 1.81243240219061 6.2662535833242e-20 759.587965390291 116.255363400366 6.53378857691393 1.79200940350339e-10 173.316823333178 154.333139330151 1.12300458660675 0.262053541059215 AURKAIP1 essential 5.34699418265054e-16 1 1.70151292862647e-06 6.53378857691393 1.12300458660675 0.00857543384244906 10.834693374028 11.9997645701127 0.902908828812649 0.367070564480807 -58.2701805366446 24.6013608453029 -2.36857549885375 0.0182898497996625 TTLL11 other 1 1 1 0.902908828812649 -2.36857549885375 0.168420153712576 -6.4900102304869 6.16070511567096 -1.05345250399638 0.292714438096123 -23.3385288158711 12.4630060934574 -1.87262436051627 0.0617862354122391 EIF4E1B other 1 1 1 -1.05345250399638 -1.87262436051627 9.91819404319348e-10 182.548354832034 34.0597660069424 5.35964794340705 1.35693688733253e-07 -22.8112531449336 40.1322575064762 -0.568401943031799 0.570056046486004 TOMM5 other 7.06175415875376e-06 1 0.0012388833781346 5.35964794340705 -0.568401943031799 5.95198975253873e-06 40.7532087367705 39.5295362785463 1.03095590217911 0.303134360108052 -222.965998648955 64.347967112655 -3.46500454720822 0.000582846490871586 SLC35E3 other 0.0338251577636776 1 1 1.03095590217911 -3.46500454720822 0.0517747922284772 -21.8408745369291 75.0937943575081 -0.290847928564491 0.771305296612947 -144.34512516328 88.039352572736 -1.63955232455879 0.101816272697193 PRIMA1 other 1 1 1 -0.290847928564491 -1.63955232455879 0.0268035110682549 7.63810140294339 6.99680410062051 1.09165574640942 0.275585934904037 -28.807218156358 15.2579282804248 -1.88801635627796 0.0596859673783217 ZNF169 other 1 1 1 1.09165574640942 -1.88801635627796 1.39257549746882e-05 248.169860747279 84.8240935591757 2.92570012049877 0.0036163121790771 -373.870782533336 173.308578113663 -2.15725491838111 0.031531552387675 RUVBL1 essential 0.0763270630162659 1 1 2.92570012049877 -2.15725491838111 1.86499632979955e-05 32.3613601859439 6.93932111815471 4.66347638838616 4.14294115234172e-06 31.43818704572 8.87804928965132 3.54111427184414 0.000441461914513825 SFN other 0.100821701588964 1 0.0365117403755876 4.66347638838616 3.54111427184414 0.000104130297368592 538.315866974768 125.862248904545 4.27702406130556 2.32714398776345e-05 -76.4189207557425 94.0822048937148 -0.8122569070535 0.417085465242888 CTDNEP1 other 0.515236711379793 1 0.199156982472796 4.27702406130556 -0.8122569070535 0.298261063308939 -187.848252688168 120.627265247013 -1.55726196978357 0.120132184830581 -106.480913978493 272.918517676203 -0.390156427951967 0.696610977178556 ETV4 other 1 1 1 -1.55726196978357 -0.390156427951967 1.32089131941363e-07 121.32522991457 22.0644055022942 5.49868565015067 6.52054013622677e-08 23.9373745390041 48.768385381724 0.490837954786476 0.623787447316126 SWI5 other 0.000844974177028896 1 0.000598650789906979 5.49868565015067 0.490837954786476 0.38115455847987 132.793568799278 107.004365188826 1.24101076217726 0.215266032267103 -116.793863502408 289.247995150755 -0.403784522141755 0.686568242105604 BAIAP2 other 1 1 1 1.24101076217726 -0.403784522141755 2.15507559839828e-18 245.350383070086 52.1264580923694 4.70683012138134 3.38249363845652e-06 -149.213079140799 58.8797697814773 -2.53419943207283 0.0116186504787518 ZDHHC21 other 1.81349611605215e-14 1 0.0298843312957634 4.70683012138134 -2.53419943207283 0.405226416503599 -19.1846774193539 25.950163034254 -0.739289282846905 0.460128271538044 54.3263440860225 58.7120997418102 0.925300650546066 0.355320221113888 ARL4D other 1 1 1 -0.739289282846905 0.925300650546066 0.949294652441034 6.77117146958159 32.7750135058702 0.206595535601193 0.836421749560489 -4.95441998654977 54.369196073406 -0.0911254965010079 0.927434532672047 DOK7 other 1 1 1 0.206595535601193 -0.0911254965010079 0.089563544775453 -58.2948595906676 505.964800975222 -0.115215247144282 0.908327800319278 -2143.19894336029 1052.34382472416 -2.03659573326433 0.0422970350326857 LRRN1 other 1 1 1 -0.115215247144282 -2.03659573326433 0.821469075637357 -1.66306807939592 4.84843694177034 -0.343011180586516 0.731754613968939 -3.5336671540449 6.19602622199293 -0.570311846244625 0.56875863985033 DENND2C other 1 1 1 -0.343011180586516 -0.570311846244625 0.000178866192844323 -4.93635851007208 4.31650085800437 -1.14360188320553 0.253414846239361 -15.2393095454406 4.92215139266483 -3.09606680691511 0.00208724128659016 PLEKHD1 other 0.857484528495683 1 1 -1.14360188320553 -3.09606680691511 7.172127646445e-06 625.647210723674 151.048703362808 4.14202304816158 4.1371538340288e-05 159.53379600396 236.953298514211 0.673271049630028 0.501132402155086 TUBB6 other 0.040422111415364 1 0.349920471282156 4.14202304816158 0.673271049630028 0.00312722004134128 29.9391628872605 13.6355504380015 2.19566954949042 0.0286417811172249 -17.1916128075528 21.0599807641995 -0.816316643402511 0.414764827041593 AMIGO3 other 1 1 1 2.19566954949042 -0.816316643402511 6.33441466196632e-26 217.300169355371 50.1796582763172 4.3304433872147 1.8490625167189e-05 -169.909820800578 66.6503266483009 -2.54927213931231 0.0111370294727044 B3GALT6 other 5.63319495888665e-22 1 0.158797488935819 4.3304433872147 -2.54927213931231 8.60368565584735e-79 46.9806132172808 6.15489240916695 7.6330519031184 1.47097571503198e-13 -27.414755193033 7.66642567010629 -3.5759500414817 0.000388194257727093 ZNF613 other 8.44193636551742e-75 1 1.42052124800639e-09 7.6330519031184 -3.5759500414817 6.70060219341769e-05 158.201292691437 91.3118720269775 1.73253804986822 0.083881727779518 -550.143728474107 180.814440509433 -3.04258734492728 0.00248659327736744 JAKMIP2 other 0.339318495074672 1 1 1.73253804986822 -3.04258734492728 0.00356748362378476 227.44511490696 80.9179037650987 2.81081323568668 0.0051653547956497 -102.231242521763 170.522161471866 -0.599518805293996 0.549139818559752 TPRN other 1 1 1 2.81081323568668 -0.599518805293996 0.0223104600998716 192.967196534435 98.9300119105231 1.95054253818309 0.0517518186297109 -241.332573768192 209.138084231338 -1.15393891387683 0.249157350590194 SLC35A4 other 1 1 1 1.95054253818309 -1.15393891387683 1.94257858455518e-12 239.491151864162 134.239569386027 1.78405780769057 0.0751096055902191 -1012.97881266914 207.331765733875 -4.88578684063962 1.44950087962599e-06 IP6K1 other 1.48684964861853e-08 0.0127150217160792 1 1.78405780769057 -4.88578684063962 5.21527719541158e-09 360.215507282253 57.7511425183798 6.23737456220215 1.05734132302782e-09 193.04376057268 121.701739559292 1.5862037902805 0.113421383443338 SSNA1 other 3.60636418062711e-05 1 9.96861399350625e-06 6.23737456220215 1.5862037902805 1.87107069365103e-07 119.339744566707 39.6020245238106 3.01347585134076 0.00273363074902357 -86.7146680703701 49.7563964972048 -1.7427843287494 0.0820779316631859 CSTF3 essential 0.00118682014098285 1 1 3.01347585134076 -1.7427843287494 1.20646247766017e-10 332.87662741914 91.0379504945077 3.65646003244792 0.000287093178360179 -528.122227897615 176.6018983826 -2.99046744533551 0.00294403875359938 YES1 other 8.85784751098093e-07 1 1 3.65646003244792 -2.99046744533551 2.39638116490139e-11 268.940097418847 37.9433220533749 7.08794282800352 5.48108355942508e-12 1.36236251821178 102.566187967481 0.013282764478326 0.989408246883467 CHMP6 essential 1.78985709206485e-07 1 5.25909967526836e-08 7.08794282800352 0.013282764478326 1.57378531810847e-10 59.7217105799204 17.1415145605626 3.48403931104908 0.000543740549150584 -19.3591308842396 20.0431284452327 -0.965873712636123 0.334641584108941 DLEU1 other 1.15075182460091e-06 1 1 3.48403931104908 -0.965873712636123 0.00202317002383716 46.8908006652197 23.2259631552638 2.01889585167075 0.0441068380818682 -78.1354999796084 46.1314849313101 -1.69375644629589 0.0910225165315862 TMEM39A other 1 1 1 2.01889585167075 -1.69375644629589 1.51039278345311e-07 110.59557411528 28.9795605749143 3.81633026592595 0.000155083834460053 -29.1775055042195 36.4102220434021 -0.801354780793125 0.423363785184053 TCP11L1 other 0.000963328517286396 1 1 3.81633026592595 -0.801354780793125 3.69039074552925e-16 379.683963622072 43.3257239511814 8.76347649839371 4.25056540070206e-17 269.327636661304 114.254563530966 2.35725933685186 0.0188514984610237 CCDC57 other 3.02243002058846e-12 1 4.13792541758346e-13 8.76347649839371 2.35725933685186 0.0150238858629722 -47.8987280233891 260.380030710279 -0.183956995061135 0.854133109891004 -808.415899344776 360.909840810263 -2.23993864376166 0.0256004194041378 FOXG1 other 1 1 1 -0.183956995061135 -2.23993864376166 3.22480119706571e-09 -108.072930441317 255.238994315041 -0.423418571803032 0.672198685417392 -1005.52099599998 289.116187495708 -3.47791316947588 0.000556093688487344 BNIP3 other 2.24865387471392e-05 1 1 -0.423418571803032 -3.47791316947588 3.40671570496504e-07 37.9698616560738 21.8486523123791 1.7378582950199 0.082940225065921 -24.3487600684034 26.8137964591572 -0.908068355985751 0.364342595428371 MYPOP other 0.00212783462932117 1 1 1.7378582950199 -0.908068355985751 7.98561537322199e-10 100.701398844432 15.2855010454158 6.58803388552533 1.28690334048933e-10 36.8845084495415 31.7250281732637 1.16263122756266 0.245615118306688 ATAD5 other 5.70731930724176e-06 1 1.22320162513511e-06 6.58803388552533 1.16263122756266 1.41695721696934e-13 60.511579086907 28.4265314044943 2.12870076288449 0.0338403099907788 -60.0634727090085 35.0274845412652 -1.71475267195533 0.0871028007864054 ZNF404 other 1.11273650248602e-09 1 1 2.12870076288449 -1.71475267195533 9.8606165962529e-09 170.224198933572 35.980468075524 4.73101679990006 3.02078112773934e-06 12.7624333482817 54.3770393134358 0.234702615468223 0.814549486716568 RTTN essential 6.73578719690036e-05 1 0.0267369337616209 4.73101679990006 0.234702615468223 0.0165315855149898 -39.4548010320628 33.0167356802757 -1.19499399983485 0.232736020687295 -193.736414449833 68.2048886955793 -2.84050627682338 0.0047141672845093 ACBD7 other 1 1 1 -1.19499399983485 -2.84050627682338 6.75233019666001e-08 420.090172050997 84.2664575379325 4.98525966707326 8.95999214802024e-07 -147.833673721995 177.578728690982 -0.832496520341978 0.405586599685847 ANAPC2 essential 0.000439441649198634 1 0.00804786494735178 4.98525966707326 -0.832496520341978 4.28130956108642e-47 99.5984888730436 15.2654626620281 6.52443303410571 1.89690868462535e-10 -52.2687518642 19.6186676221492 -2.66423555721946 0.00800242231080173 ZBTB8OS other 4.06381903538323e-43 1 1.80035603257792e-06 6.52443303410571 -2.66423555721946 3.14631688830343e-08 -1.47361611763395 17.7426153737087 -0.0830551802310711 0.933845780982816 -73.0576662264888 21.3035284968641 -3.42936928205311 0.000662544924980248 SLC35G1 other 0.000209009830889997 1 1 -0.0830551802310711 -3.42936928205311 2.00898946854381e-39 148.038638285362 96.8431354560617 1.52864359036091 0.127076305260322 -655.359348001903 120.890048460062 -5.42111907762542 9.8148396625202e-08 ZNF135 other 1.87298088152339e-35 0.000890794847770333 1 1.52864359036091 -5.42111907762542 2.12728915222353e-05 50.2937939025273 12.8386489945978 3.91737432214944 0.000103922904359662 1.22211900784344 22.3634925716269 0.0546479492829296 0.956444026944183 OR4N2 other 0.114256700365926 1 0.862767951993916 3.91737432214944 0.0546479492829296 1.69748264601512e-05 18.0652525298704 16.047011551943 1.12577051941382 0.260881957188669 -101.606760688477 30.4621500272645 -3.33550851130128 0.00092425394935147 ZSCAN2 other 0.0922581818109217 1 1 1.12577051941382 -3.33550851130128 0.257278497699442 -63.7803861704743 152.630237469773 -0.417875168300813 0.676243169047541 -254.298209423219 195.004063294543 -1.30406620829801 0.192895906969257 PRR18 other 1 1 1 -0.417875168300813 -1.30406620829801 0.000902842382490554 136.15132947977 59.7426056727124 2.27896537063761 0.0231495640576915 -214.810820809247 119.084792084838 -1.80384763703674 0.0719421318905521 B3GNT4 other 1 1 1 2.27896537063761 -1.80384763703674 7.0378099453826e-08 55.2808575529245 9.70605787904515 5.69550050513019 2.26189878476872e-08 21.7636795837822 19.6340407502659 1.10846666056183 0.268270008671887 CDC26 essential 0.00045766878074823 1 0.000209248256578954 5.69550050513019 1.10846666056183 0.896514055937646 2.22771418475411 4.92877750374851 0.451981081122013 0.651506354193941 3.08658050377094 11.3754741452016 0.271336426453303 0.786260127014565 HSD11B2 other 1 1 1 0.451981081122013 0.271336426453303 2.82240065976113e-05 72.9415482861978 15.7454921006028 4.63253531996027 4.77612112923453e-06 44.7187540727223 32.6797387281809 1.36839386767067 0.171893527995693 CRLF3 other 0.149872759958874 1 0.0419821047259715 4.63253531996027 1.36839386767067 3.79778897784295e-52 115.122793403813 16.5752204647164 6.94547584744797 1.37005397812708e-11 -92.1899782457674 23.5437660923824 -3.91568527668968 0.000104523780487467 EID2 other 3.63828184077355e-48 0.83023238841195 1.31073064087418e-07 6.94547584744797 -3.91568527668968 0.330412069654383 1.31995864816939 3.39884055867825 0.388355565782321 0.697956480614229 -3.33591858344876 4.01135863520723 -0.831618134107928 0.406113359564336 DMRTA1 other 1 1 1 0.388355565782321 -0.831618134107928 9.40671844549733e-15 36.8498056146849 11.2149918202128 3.28576303981518 0.00109881562638789 -29.0882733106514 15.9299928893941 -1.82600667260924 0.0685299035421444 EID2B other 7.53101878746516e-11 1 1 3.28576303981518 -1.82600667260924 0.00861593393757232 -35.0080341771352 35.5752274894045 -0.984056509197638 0.325633480577074 -169.548304063738 57.3698652201477 -2.9553547565978 0.00329241624038643 SPRYD4 other 1 1 1 -0.984056509197638 -2.9553547565978 0.687340593373024 0.263875061435975 45.1701722502324 0.00584179887502239 0.995341623437281 -36.3201377424355 59.8751682572566 -0.606597673118583 0.544434385137209 CLEC14A other 1 1 1 0.00584179887502239 -0.606597673118583 9.54164440525501e-06 32.6991180849867 60.4292719429509 0.541113884606399 0.588704815041067 -173.483016182075 71.6104093738756 -2.42259495091455 0.0158157310680154 SYNE3 other 0.0531755842704862 1 1 0.541113884606399 -2.42259495091455 0.0124648340752787 -75.0425374605668 84.4811022500056 -0.888276022233858 0.374880947666422 -380.171628548896 135.398147930373 -2.80780523485738 0.00521140231600905 LPCAT4 other 1 1 1 -0.888276022233858 -2.80780523485738 0.297996297578095 -17.9748743718603 119.783813428349 -0.150060962807902 0.880785594588852 -328.604690117255 233.795215990735 -1.40552358492347 0.160574553653942 SLCO3A1 other 1 1 1 -0.150060962807902 -1.40552358492347 1.00930798184637e-44 23.5371930670615 8.65839417058623 2.71842475675462 0.00682157243229923 -53.5413584528759 10.6689684944974 -5.01841939832238 7.60865365181858e-07 ZNF575 other 9.53392319652082e-41 0.00673670194332017 1 2.71842475675462 -5.01841939832238 3.07622848111705e-19 99.9238781133214 25.0543578042674 3.9882833515015 7.79814899907016e-05 -63.0895654308863 29.6586434527643 -2.1271898538234 0.0339624871809722 WDR25 other 2.61079511192404e-15 1 0.651925256322265 3.9882833515015 -2.1271898538234 5.22538843749847e-39 51.193743019033 11.08749682816 4.6172498457011 5.13020383138556e-06 -30.0105039519344 13.4349123678094 -2.23376998154754 0.026006965525773 PHLDB3 other 4.86483663531107e-35 1 0.0450431896395652 4.6172498457011 -2.23376998154754 0.0017608196028996 -8.70421743799904 37.049277668178 -0.234936225098801 0.81436802554356 -242.938480779776 73.5873979924974 -3.30135984431117 0.00104092106862906 USF3 other 1 1 1 -0.234936225098801 -3.30135984431117 7.923388589014e-07 124.387794308181 28.3533587195103 4.3870567694891 1.44178475048827e-05 -117.576810525845 62.1017078410175 -1.89329431691067 0.0589791002274387 CNTD1 other 0.00483722873359305 1 0.124483695357157 4.3870567694891 -1.89329431691067 4.00970968185121e-07 62.7542305564245 121.486581627964 0.516552772458448 0.605729091117302 -706.255964413477 187.618188404559 -3.76432567875873 0.000189756799874549 MEX3C other 0.00249484136404782 1 1 0.516552772458448 -3.76432567875873 0.419892555243411 23.192268122457 38.2533177815511 0.606281218661829 0.544642110001956 -30.5041773641916 60.8566950038105 -0.501246039770671 0.616449795184873 RNF152 other 1 1 1 0.606281218661829 -0.501246039770671 0.00902409697073929 -169.604425748472 86.4801117726859 -1.96119572780248 0.0504907921062285 305.394640270048 177.95144455134 1.71616836851211 0.0868399295161418 MYO1D other 1 1 1 -1.96119572780248 1.71616836851211 0.443775077193324 -3.31595704402296 2.64933154063643 -1.25162026464472 0.211376288759148 -4.14395530008377 5.6293569752659 -0.736132975451967 0.462043825620214 FOXL1 other 1 1 1 -1.25162026464472 -0.736132975451967 0.373069619790427 28.9183140170078 23.5388781446094 1.22853408048379 0.219909256957664 -26.6466204977504 55.1157565642887 -0.483466474177289 0.629007262004273 LRRC37A other 1 1 1 1.22853408048379 -0.483466474177289 0.547668762658026 -3.88051147902105 3.62645283233811 -1.07005706634798 0.285182938565438 -5.09467754334035 7.70556543568392 -0.661168552245012 0.508851853144339 FOXC2 other 1 1 1 -1.07005706634798 -0.661168552245012 0.256748928922797 -12.9120068914845 38.6886549426577 -0.333741426540209 0.738735506846755 -70.2935214978844 48.5161864220978 -1.44886741275006 0.14809507213921 BDNF other 1 1 1 -0.333741426540209 -1.44886741275006 1.6772064254588e-08 134.198352454067 26.9169993566492 4.98563568234125 8.92162825521694e-07 -68.1584461887931 57.1955344589916 -1.19167425977393 0.234035767421257 ACSF3 other 0.000113362382296761 1 0.00801429866166137 4.98563568234125 -1.19167425977393 0.675390604104781 -9.57029030265584 215.033383563919 -0.0445060675883893 0.96452129843171 -203.249935425908 314.821088718446 -0.645604575771228 0.518873535685142 BOK other 1 1 1 -0.0445060675883893 -0.645604575771228 0.0326873594528908 -108.880358442976 280.451589236379 -0.388232274737462 0.698033207287418 -1499.7846547578 577.089511198982 -2.5988769950814 0.00966921606153257 CDK5R1 other 1 1 1 -0.388232274737462 -2.5988769950814 0.00119399761793614 -14.267375369923 14.1971611500399 -1.00494565210193 0.315477872212475 -44.4511619941752 16.4813708949326 -2.69705489170457 0.00726544409892468 TCERG1L other 1 1 1 -1.00494565210193 -2.69705489170457 0.000442713790485984 102.340311994497 55.6224863832029 1.8399089765502 0.0664596194870927 -251.021270661734 109.413727478073 -2.29423927369661 0.0222502373293267 RUFY1 other 1 1 1 1.8399089765502 -2.29423927369661 0.880582151837766 -155.871134020622 453.362504891315 -0.343811259949671 0.73115473636529 -414.907413801605 830.449002267075 -0.499618173625272 0.617597149007863 BASP1 other 1 1 1 -0.343811259949671 -0.499618173625272 0.0011077501339467 19.6165937404193 36.174236454446 0.542280796033452 0.587902133027681 -216.907060065836 71.0976449707495 -3.05083326114493 0.00242135365853638 VSIG10 other 1 1 1 0.542280796033452 -3.05083326114493 0.00304457899285528 25.716228853184 7.95972570668304 3.23079334650847 0.001327532308886 38.5341395335654 18.209320876812 2.11617664350324 0.0348933493206993 IRX5 other 1 1 1 3.23079334650847 2.11617664350324 0.0117752694490553 67.3361595173384 34.2014519684506 1.9688099668825 0.0496167064886497 231.439246653789 88.8071524932318 2.60608791247335 0.00947623344270079 METRNL other 1 1 1 1.9688099668825 2.60608791247335 1.3093941087024e-05 69.7594827345911 179.904402927643 0.387758618462762 0.698383904810611 -1454.29321925254 353.588095332202 -4.11295866136615 4.6700705303434e-05 WSB2 other 0.0719381123321097 0.380984353865415 1 0.387758618462762 -4.11295866136615 0.409678568349739 -600.859873334163 525.067235479286 -1.14434844289169 0.253109890992534 -1207.10746482651 1106.49925104218 -1.09092479157991 0.275911260745181 GRIN1 other 1 1 1 -1.14434844289169 -1.09092479157991 1.45046943320239e-10 619.264771958318 92.4381842719675 6.69923124124057 6.51656435323952e-11 392.65729615514 179.318171562473 2.18972395677335 0.0290759387629199 TYMS other 1.06232381287743e-06 1 6.20898251576661e-07 6.69923124124057 2.18972395677335 0.000162308265292125 110.242110602298 26.143560965289 4.21679780916864 3.01350529803496e-05 71.4078370010979 46.893103850798 1.52277906850226 0.128537266375251 PXMP2 other 0.78378661309567 1 0.256569841074697 4.21679780916864 1.52277906850226 3.46569570300124e-37 -87.3443251147247 412.667307993417 -0.211657971016493 0.832472329715615 -3641.93982972105 473.063574627307 -7.69862662241597 9.22933650603542e-14 PNMA1 other 3.21235334711185e-33 8.91277026387841e-10 1 -0.211657971016493 -7.69862662241597 5.39209525040585e-20 18.3058979015749 6.57340838009654 2.78484111180478 0.0055875693187647 -15.4165619269362 8.01723023496072 -1.92292867675289 0.0551370671037721 MAMSTR other 4.60646697242172e-16 1 1 2.78484111180478 -1.92292867675289 6.82623625431445e-13 386.466868118459 51.3240565244413 7.52993614085078 2.93485331679144e-13 73.7545039548778 92.0587794386659 0.801167519324072 0.423470054530657 ANKLE2 essential 5.27668062458507e-09 1 2.83125299470871e-09 7.52993614085078 0.801167519324072 1.13139841903389e-27 5.03282302763065 2.00114992440737 2.51496550370713 0.0122614858449667 -7.74649001710175 2.44069419560579 -3.1738879991801 0.00161012969068278 FUT2 other 1.01543008108291e-23 1 1 2.51496550370713 -3.1738879991801 0.042650648313629 5.97098425733779 3.23696605094609 1.84462368877567 0.0657704087096562 -7.42347429607699 6.66090274155619 -1.11448471537698 0.265685258641508 EFCAB5 other 1 1 1 1.84462368877567 -1.11448471537698 0.0251193914778015 20.9012567405364 15.1569897584341 1.37898468453513 0.168603246134172 -31.7380148336586 26.5675460083614 -1.19461597332588 0.232883598622871 MUC20 other 1 1 1 1.37898468453513 -1.19461597332588 9.55387427516711e-15 100.166399011736 48.9132753215075 2.04783667324139 0.041171834591155 -295.561384693133 71.6118136369494 -4.1272713213429 4.39552483089396e-05 THAP4 other 7.64692096984375e-11 0.359202289180655 1 2.04783667324139 -4.1272713213429 0.00185172441952533 337.753032226816 94.5306145628837 3.57294865571974 0.000392261939842269 325.864893224012 300.505769716497 1.0843881418032 0.278790625285247 LY6H other 1 1 1 3.57294865571974 1.0843881418032 0.00339887877729472 -121.463869243397 258.30108759987 -0.470241416217168 0.6384182175736 -917.441589481782 322.748501815984 -2.84258976980431 0.00468548548083155 FIBIN other 1 1 1 -0.470241416217168 -2.84258976980431 0.00713403402171562 581.036028211461 218.271590430697 2.66198650527516 0.00805654391860678 -227.96016282282 456.996832339757 -0.498822194577798 0.618157376974695 DPP7 other 1 1 1 2.66198650527516 -0.498822194577798 1.1186427778345e-31 95.7685726062926 176.871008110604 0.541459980520975 0.588465875684906 -1551.73657401955 214.420031120706 -7.2369011696767 2.07174120897524e-12 SEC24C other 1.01830052066274e-27 1.98804286413264e-08 1 0.541459980520975 -7.2369011696767 0.566339681441146 44.1453690035622 50.6820979497482 0.871024894181231 0.384217710259293 -25.1256592443207 37.6165889167233 -0.66794092627443 0.504523100801962 SMCR8 other 1 1 1 0.871024894181231 -0.66794092627443 8.24376290690477e-54 113.947026493337 40.1484643146339 2.83814159366996 0.00474858895129272 -361.403975645877 51.2977612412305 -7.0452192630075 7.22481067231302e-12 MTHFR other 7.92143177724479e-50 6.90186163526063e-08 1 2.83814159366996 -7.0452192630075 1.39110924026493e-25 27.1098672842914 5.74831164516864 4.71614431466616 3.2385205221325e-06 -4.30159277232435 7.17566268456128 -0.599469757905342 0.549170339515262 C19orf18 other 1.23488767258318e-21 1 0.0286285214156513 4.71614431466616 -0.599469757905342 1.79328721752255e-19 1061.42494989476 222.171648998817 4.77749953550741 2.42570337500936e-06 -327.005077171251 257.856748554121 -1.26816567340147 0.205412451870361 DEAF1 other 1.52411480617241e-15 1 0.0215184146397081 4.77749953550741 -1.26816567340147 3.53135284705595e-18 63.7049214479168 40.7099524881006 1.56484882822051 0.118340534206114 -202.488963278507 47.2487647711985 -4.28559274002308 2.24270699557196e-05 TMEM80 other 2.96139249754112e-14 0.186346524262074 1 1.56484882822051 -4.28559274002308 3.66938770336878e-46 102.409066297679 24.6062502418074 4.16191273726382 3.80216556974164e-05 -110.984446007607 30.1707096034245 -3.67854940988891 0.000263818820136461 SIX5 other 3.47784566525293e-42 1 0.322157488724209 4.16191273726382 -3.67854940988891 1.10729455557864e-43 14.9707616411998 26.4147043108579 0.566758630534661 0.57116915545308 -221.675703192246 32.3881276176389 -6.84435067717591 2.60937563455723e-11 FBXO46 other 1.0432929302662e-39 2.48229904115429e-07 1 0.566758630534661 -6.84435067717591 0.0103340993527089 21.0826908063732 18.8684509319675 1.11735143930943 0.264458006804222 -32.4950797894663 23.6573853643457 -1.37357021027522 0.170279377597955 ZDHHC13 other 1 1 1 1.11735143930943 -1.37357021027522 0.11633162554526 5.37081919172278 2.68817331710867 1.99794379236659 0.0463477746719606 5.49284571565267 3.03361663823861 1.81065914737399 0.0708865948206805 ACER2 other 1 1 1 1.99794379236659 1.81065914737399 1.61512284541059e-10 191.633314938234 53.6952321016427 3.56890746976344 0.000398280323906466 -320.925457401197 101.930020473562 -3.1484881089025 0.00175391724574412 WDR73 essential 1.18065479999514e-06 1 1 3.56890746976344 -3.1484881089025 0.000737807729544147 258.247847599733 71.5471305618816 3.60947875297909 0.000342252623454134 -4.58663587114573 129.343017996251 -0.0354610240444418 0.971728280068395 POLE other 1 1 1 3.60947875297909 -0.0354610240444418 2.97287208919099e-05 -13.4031029132909 10.7034253489551 -1.25222557044314 0.211157442332758 41.9768463565394 16.1662543394059 2.5965721851981 0.0097333150777309 FAM109B other 0.157502763285339 1 1 -1.25222557044314 2.5965721851981 0.10071801121928 263.527894854978 123.517045708864 2.13353463356083 0.033438495916624 256.818735993787 143.022818895663 1.7956486802371 0.0732427159276695 RHOG other 1 1 1 2.13353463356083 1.7956486802371 0.000821864784864213 -38.3908639651731 42.1511535009527 -0.910790352731519 0.362906805624359 -143.668429828321 48.9214507725925 -2.9367164619903 0.00349192544797049 EPS8L2 other 1 1 1 -0.910790352731519 -2.9367164619903 5.73686349634262e-07 -55.7493972013183 770.793794198626 -0.0723272522702125 0.942374492455635 -2662.64442951551 888.786835178778 -2.99581893444666 0.00289245121477632 ZDHHC22 other 0.0035396447772434 1 1 -0.0723272522702125 -2.99581893444666 1.66038806363218e-07 -2.7647301010943 2.22342059632623 -1.24345798795895 0.21436425033177 -12.7996418544202 2.69650567925525 -4.74675130591803 2.80388921723394e-06 MRVI1-AS1 other 0.00105683700250188 0.0243153272918527 1 -1.24345798795895 -4.74675130591803 0.240714064572248 318.787386880346 258.576126958617 1.23285699507505 0.218299591346581 647.333353081451 387.590802246844 1.67014632269108 0.0956147549270509 ANO6 other 1 1 1 1.23285699507505 1.67014632269108 1.43467350111922e-08 94.7070328416584 16.4854677231157 5.74487994106841 1.72371145252241e-08 2.90049710700005 36.4371573369976 0.0796027275172463 0.936589581879966 ZBTB34 other 9.72995568459057e-05 1 0.000159805288763353 5.74487994106841 0.0796027275172463 0.476781213931319 -11.9600631890736 49.5678162744977 -0.241286868940139 0.809445700220722 -52.9747164719434 63.3328832846928 -0.836448835493759 0.403358550093686 LINC00982 other 1 1 1 -0.241286868940139 -0.836448835493759 4.29551135081821e-15 38.6213233861101 16.4151342803508 2.35278753901761 0.0190777888154269 -118.803569618872 25.7507686374522 -4.61359314323856 5.21381372662985e-06 FAM210A other 3.46003439308407e-11 0.044750163215664 1 2.35278753901761 -4.61359314323856 4.58531515036839e-18 1275.53844993427 214.198454610435 5.95493768736148 5.34333966820101e-09 112.725687485379 248.602903656076 0.453436729127374 0.6504588542111 TALDO1 other 3.83745024934331e-14 1 4.99335091993385e-05 5.95493768736148 0.453436729127374 0.000470736037270962 292.724705187339 84.8185946355228 3.45118551474729 0.000612290384233654 -118.886778305423 154.679812984629 -0.768599185707813 0.442545503784182 ULK1 other 1 1 1 3.45118551474729 -0.768599185707813 3.04208754574888e-05 12.679047883084 51.7674303974295 0.244923261319798 0.806630554759729 177.954332182858 66.4783142835847 2.67687792779668 0.00771014313028094 RIMKLA other 0.160896010294658 1 1 0.244923261319798 2.67687792779668 7.03643547020446e-09 126.383654086478 20.636502164461 6.12427692829303 2.02834368083501e-09 117.279513454971 37.6338503269526 3.1163304428348 0.00195163373717024 PUS1 other 4.84036395995365e-05 1 1.906845894353e-05 6.12427692829303 3.1163304428348 0.0768012154157777 251.70493285324 192.846460850283 1.30520898202354 0.192506929266101 -633.650535474193 456.116751507495 -1.38922881779706 0.165469033862845 CHD9 other 1 1 1 1.30520898202354 -1.38922881779706 6.41255668561833e-09 115.891945088972 198.140791901525 0.58489695118696 0.558918182944487 -751.922935708055 229.966067164303 -3.2697125492468 0.00116150284422209 GATD1 other 4.42017532339671e-05 1 1 0.58489695118696 -3.2697125492468 1.99077246244119e-10 31.5551845334356 26.0482353098221 1.21141352410684 0.226391619343039 -74.4353457067116 30.2630035993334 -2.45961526794225 0.0142949201378885 LINC01561 other 1.45167127961212e-06 1 1 1.21141352410684 -2.45961526794225 2.07420584088133e-15 658.939119333641 86.6002379592478 7.60897585112552 1.73401506828654e-13 -97.2828994181908 181.315554393283 -0.536539182993528 0.591860875213293 MAN1B1 other 1.67865478702526e-11 1 1.67401814692383e-09 7.60897585112552 -0.536539182993528 0.00495270690016119 10.9199167180394 5.4477539787771 2.00448051813285 0.045633683599561 21.6760029311529 7.02872316018587 3.08391758177877 0.00217216446841405 KCNA3 other 1 1 1 2.00448051813285 3.08391758177877 0.000864702919892027 0.119447367527866 4.19491645091383 0.0284743138333172 0.977296823439587 -14.5281238331239 5.54103373640202 -2.62191578760492 0.00904823702412986 CLDN22 other 1 1 1 0.0284743138333172 -2.62191578760492 0.0167074638292669 -213.791213520525 199.882322083013 -1.06958540051249 0.285395045688632 136.849055538971 257.889308513153 0.530650364406214 0.59593002999075 KCNA2 other 1 1 1 -1.06958540051249 0.530650364406214 2.98275344631329e-06 180.628334338225 36.405180869363 4.96161068355615 1.00243425269693e-06 -42.027332217556 27.0201664611358 -1.55540611779744 0.120571613692517 TOP3A essential 0.0174192801264696 1 0.00898882794393335 4.96161068355615 -1.55540611779744 0.0146646063590537 -94.2282970640667 124.138860630456 -0.759055597783927 0.448227588581966 -784.347821498922 271.118748317882 -2.89300473082477 0.00400604422980516 ZBTB38 other 1 1 1 -0.759055597783927 -2.89300473082477 7.58124545944216e-19 39.0797428311543 4.58871817751153 8.51648354058374 2.676184671944e-16 -24.1269390884847 14.5871926710884 -1.65398097032776 0.0988494552977547 C8orf31 other 6.41145928505024e-15 1 2.60125150112957e-12 8.51648354058374 -1.65398097032776 0.000154007368413823 30.508289769844 8.11748927446027 3.7583406319773 0.000194317236807229 17.4642066286298 10.0470688036577 1.73823897993729 0.0828746888929057 RPL13AP3 other 0.746319707333386 1 1 3.7583406319773 1.73823897993729 8.77203602231638e-09 86.4746983974544 24.4814165189704 3.53225877801826 0.000455874481763884 -79.2101524518341 38.1732870989827 -2.07501523896654 0.03856971413839 CCDC71 other 6.01147628609342e-05 1 1 3.53225877801826 -2.07501523896654 0.00516779062760025 73.0133576120179 28.1580543224522 2.59298305116911 0.00983611041113726 -42.441204396176 20.0270562158863 -2.11919335216675 0.034641411250014 TIMM22 essential 1 1 1 2.59298305116911 -2.11919335216675 0.0125297299687151 159.545040322391 61.7895269510824 2.58207253227071 0.0101446064662761 60.6655488104547 47.4307345546337 1.27903456229581 0.201562092011651 HIC1 other 1 1 1 2.58207253227071 1.27903456229581 0.0206724243846828 -193.163488171524 116.531869937692 -1.65760223597894 0.0981137880996551 -61.1505202645635 142.127611275423 -0.430250812743643 0.667224817888229 PPFIA3 other 1 1 1 -1.65760223597894 -0.430250812743643 0.2423224178628 38.4432187956134 45.6228390749899 0.842631006203377 0.399895780214278 -50.3132959277948 73.5687977304269 -0.683894497123011 0.494404266392977 PAWR other 1 1 1 0.842631006203377 -0.683894497123011 0.000859033882136036 198.472797445294 58.263078386964 3.40649349365139 0.000718900748871019 47.7950551495811 114.065498734427 0.419014125041088 0.675411686302699 TGIF1 other 1 1 1 3.40649349365139 0.419014125041088 0.00115204567908058 18.5762497054624 16.9041633777773 1.09891565115155 0.272408532433039 -45.1748192925556 12.5463820655857 -3.60062518871225 0.000353771332111544 MIEF2 other 1 1 1 1.09891565115155 -3.60062518871225 0.0519906512194338 -95.7838576553463 126.480590973264 -0.757300838953178 0.449276848218209 -408.216421063994 183.877686728293 -2.22004327075963 0.0269270477981002 NAP1L5 other 1 1 1 -0.757300838953178 -2.22004327075963 0.00311166005130395 0.900548899250217 36.619030820985 0.0245923739394584 0.980391483901956 -252.384093726023 83.4379325249748 -3.02481240951745 0.00263666599174334 NIM1K other 1 1 1 0.0245923739394584 -3.02481240951745 0.000298027686060431 257.072897148283 124.150172921792 2.07066080616919 0.0389757993403607 -626.306943196692 266.492647691131 -2.35018469973923 0.0192069289105136 NR2C2 other 1 1 1 2.07066080616919 -2.35018469973923 0.0100360957012522 77.2281464324386 26.555849747369 2.90814066080074 0.00382112163709764 69.9478332700866 32.5611916942445 2.14819635371179 0.0322471938655779 GPR4 other 1 1 1 2.90814066080074 2.14819635371179 0.226972466759865 -9.59753945444485 5.72256421722214 -1.67713966853546 0.0942286257744778 -10.7522635434451 6.56009485654873 -1.63904086428132 0.10192279005345 ACOT4 other 1 1 1 -1.67713966853546 -1.63904086428132 0.450061377028597 -131.530017382 360.857025095435 -0.364493437109102 0.715665480529718 851.026808396846 790.367736384709 1.0767479101432 0.282185600591487 CAVIN1 other 1 1 1 -0.364493437109102 1.0767479101432 2.25869203307363e-11 267.971908308717 98.8289146172278 2.7114727440506 0.00696318709472847 -584.87366765121 157.385790511727 -3.71617835224859 0.000228578971600273 ARIH2 other 1.68837229472254e-07 1 1 2.7114727440506 -3.71617835224859 0.240168720950609 -30.557638357562 30.3990781883734 -1.00521595320115 0.315347875339208 -112.024122247725 69.5434226617415 -1.61085143583757 0.107932475694327 IRX3 other 1 1 1 -1.00521595320115 -1.61085143583757 0.746867377191357 -37.1837591707489 259.909267323827 -0.143064383789058 0.886305124102854 -276.150016718792 415.215856501466 -0.665075797069942 0.5063520473326 ST8SIA3 other 1 1 1 -0.143064383789058 -0.665075797069942 0.0112510637642559 185.45359787942 180.458288895639 1.02768123877463 0.304666983555864 -182.104960398701 209.443409336704 -0.869470951487171 0.385065799598525 SLC25A22 other 1 1 1 1.02768123877463 -0.869470951487171 0.00513152469369052 19.1459070320876 9.65499915031416 1.98300452791491 0.0479911151362194 3.57746820584451 12.3393025940778 0.289924667830213 0.772011070720277 NHLH2 other 1 1 1 1.98300452791491 0.289924667830213 0.623132278523145 53.9464440321572 78.0874819854365 0.690846249110944 0.490028118694379 -40.8129251700694 148.295455277947 -0.275213593657167 0.783281923115766 ATOX1 other 1 1 1 0.690846249110944 -0.275213593657167 2.785522262772e-12 80.8852015275417 141.515923237242 0.571562547007116 0.567911554789733 -1159.69025225458 220.199374281683 -5.2665465378257 2.18380706695391e-07 C18orf32 other 2.12563203872131e-08 0.00196542636025852 1 0.571562547007116 -5.2665465378257 9.19182385469829e-08 294.368738641019 92.0587470722645 3.19761834700992 0.00148612887667234 -35.4281721145879 106.845177154655 -0.331584195544052 0.740361851094494 PIDD1 other 0.000594619085160432 1 1 3.19761834700992 -0.331584195544052 1.69162677506971e-11 8434.34371834749 1322.47164843605 6.37771231490816 4.57221615932988e-10 4684.41644617167 1534.88638562765 3.05196299220291 0.00241180676522783 RPLP2 essential 1.2690584066573e-07 1 4.32348760026233e-06 6.37771231490816 3.05196299220291 8.90720955388598e-14 2303.86264558936 873.626525481252 2.6371253371917 0.00865854534879046 -2053.6402027175 1121.82157833593 -1.8306299703771 0.0678350690561298 JUN og 7.01799040750676e-10 1 1 2.6371253371917 -1.8306299703771 2.46223844084069e-32 71.3915151479116 71.7688306392231 0.994742627294455 0.320415735399785 -651.399906955864 91.160482255713 -7.14563910630301 3.81361039858087e-12 CSTF2T other 2.24925481570797e-28 3.65267603976075e-08 1 0.994742627294455 -7.14563910630301 0.576837039695679 -15.8788330174471 27.8940000224985 -0.569256220141956 0.569474741733242 -29.3629048394541 31.6240478126842 -0.928499255167357 0.353661214355137 CASC2 other 1 1 1 -0.569256220141956 -0.928499255167357 1.36059989933297e-10 77.9751826830283 32.2592310759801 2.41714325116348 0.0160522944004338 -316.640168600185 65.9105359601386 -4.80409033226013 2.14173397049243e-06 ACAD9 other 9.97591846190934e-07 0.0186694950207825 1 2.41714325116348 -4.80409033226013 0.396365417047528 -53.1163410962214 76.4848087224774 -0.694469163006634 0.48775622710387 67.354478374812 125.825598756801 0.535300281026251 0.592713905573035 IL17RA other 1 1 1 -0.694469163006634 0.535300281026251 2.03595765559235e-11 532.467663264062 97.9421513212441 5.4365526597185 9.04117088308374e-08 172.335022265005 113.673570862438 1.51605180480831 0.130227596928387 PNPLA2 other 1.52411790097644e-07 1 0.000827809606055147 5.4365526597185 1.51605180480831 5.89159543853701e-47 99.4161219900175 51.4296829363189 1.93304948259386 0.0538743214172109 -463.884144588887 65.7117934898909 -7.05937427594714 6.59390577199284e-12 AGTRAP other 5.58994575208391e-43 6.30047696513916e-08 1 1.93304948259386 -7.05937427594714 0.950557800096023 4.03635593037713 12.8323697599084 0.31454485850211 0.753257028275771 3.30999718245336 14.893498596447 0.222244435114997 0.824227195359269 CRACR2B other 1 1 1 0.31454485850211 0.222244435114997 0.00180595304693624 10.8685710196011 3.74498128995753 2.90216964467782 0.00389416415681887 -4.98650014761273 7.40063487291715 -0.673793564098261 0.500800426795185 DNAJC28 other 1 1 1 2.90216964467782 -0.673793564098261 0.0015167050308787 833.792108155483 329.676350358528 2.52912320598284 0.0117847299029993 179.536041051575 382.62880147724 0.469217268429423 0.639147818628956 CD151 other 1 1 1 2.52912320598284 0.469217268429423 0.00122606830701422 328.79775442327 133.992548985467 2.4538510306191 0.0145219695684071 49.4689906238745 155.514365435778 0.318099170358017 0.750561321118289 POLR2L essential 1 1 1 2.4538510306191 0.318099170358017 2.03687239226915e-11 1041.13254491924 144.254891176345 7.21731191524389 2.37158160560146e-12 778.257522544486 544.509252676668 1.42928245703589 0.153639148362719 FAM20C other 1.52459898561346e-07 1 2.27980139746468e-08 7.21731191524389 1.42928245703589 0.0379234539516475 42.0455909510619 42.9357353588013 0.97926798271182 0.327988157288215 -138.134217121753 83.9098467628323 -1.64622177790627 0.100435408671324 NECTIN3 other 1 1 1 0.97926798271182 -1.64622177790627 0.107171037942294 21.4165732160775 14.0578114342784 1.52346425446109 0.128375965862498 -19.39392669539 32.0312879834591 -0.605468212998647 0.545186619640224 ANXA2R other 1 1 1 1.52346425446109 -0.605468212998647 0.004696316159376 215.676836008427 121.855057113301 1.76994571352004 0.077431831326779 241.171348947289 90.4416307983094 2.66659664159657 0.00794602776682151 FLII other 1 1 1 1.76994571352004 2.66659664159657 0.000328756754927855 3.17997382198958 1.56789619661648 2.02817879707341 0.0431480734909955 -4.00232032365533 2.42487681332841 -1.65052521499502 0.0995540309025049 YIPF7 other 1 1 1 2.02817879707341 -1.65052521499502 0.172665403897848 -26.7380226121774 22.1116016592688 -1.20923047657062 0.227226626896365 -48.9220645389234 26.805808179395 -1.82505463784258 0.0686737110398734 MYOZ1 other 1 1 1 -1.20923047657062 -1.82505463784258 4.25031792530937e-21 719.57260051578 119.60976270379 6.0160022413704 3.77748073919358e-09 -17.6258561391001 138.821423188399 -0.12696783921585 0.899024119563559 CHID1 other 3.67439984642995e-17 1 3.53874395647655e-05 6.0160022413704 -0.12696783921585 0.546455532030755 93.4689195298428 86.6935103134165 1.07815359179634 0.281559980690625 35.1391172119073 182.777585870443 0.192250691158679 0.847635145421693 PCDHB9 other 1 1 1 1.07815359179634 0.192250691158679 7.42014167719611e-05 24.4942981197072 9.32767539200831 2.62598097492686 0.00894326855375648 -22.6495155734177 15.6199591332552 -1.45003680100523 0.147765568297259 ZNF620 other 0.37382673769714 1 1 2.62598097492686 -1.45003680100523 4.07276768430132e-06 122.236927943281 55.7320617073172 2.19329635758357 0.0288110173538576 -72.0651663844498 70.418907979273 -1.0233780734808 0.306693998873705 ZNF518A other 0.0235283789122087 1 1 2.19329635758357 -1.0233780734808 9.06170694751467e-55 69.160660737065 17.2745919396129 4.00360604631538 7.32640833667388e-05 -137.389284078687 22.1835571761214 -6.19329366286548 1.35831860673764e-09 SVBP other 8.71736208350911e-51 1.27029956102105e-05 0.61329364186297 4.00360604631538 -6.19329366286548 2.7927560348926e-05 10.3664561504241 13.9048701344097 0.745527002425627 0.456353993959208 -78.2900387541264 23.2848479524476 -3.36227399526124 0.000841041891320035 ZNF619 other 0.148351200573495 1 1 0.745527002425627 -3.36227399526124 0.0516124941864721 -40.9736886494809 79.0898531370014 -0.518065049109464 0.604674466129691 -267.211701983516 120.760290714311 -2.21274477233309 0.0274302359872722 CCDC184 other 1 1 1 -0.518065049109464 -2.21274477233309 1.27266921638386e-08 -3.68528363130135 110.307573652629 -0.0334091623020078 0.973363522391796 -869.170657993943 175.644647061578 -4.94846084144667 1.06872069630024e-06 UBE2N essential 8.65542334062665e-05 0.00941115445161992 1 -0.0334091623020078 -4.94846084144667 0.00777243340742587 126.302995530862 40.9248092818441 3.08622074842252 0.00215576788998761 76.3828015805913 78.4841249740086 0.973226134659549 0.330978085847171 ZNF354C other 1 1 1 3.08622074842252 0.973226134659549 3.87457836171944e-06 173.197637423539 36.8876906374409 4.69526919225851 3.57210088840362e-06 10.1398302475468 77.7324637489462 0.130445244605852 0.896274335180825 MAMDC4 other 0.0224221849792704 1 0.031541650844604 4.69526919225851 0.130445244605852 0.0102940481584731 29.8647825602554 22.1409552123423 1.34884797308146 0.178085938656039 -87.2935096124087 45.637993316651 -1.91273768341957 0.0564364823874017 CENPBD1 other 1 1 1 1.34884797308146 -1.91273768341957 1.2589042018802e-21 158.07639671692 54.5134620009397 2.89976807406205 0.00392266755058196 -230.105535149297 63.2835467906327 -3.63610364492652 0.00030977647682186 BET1L other 1.09165514663964e-17 1 1 2.89976807406205 -3.63610364492652 5.6534955906141e-06 60.2219391816605 76.0364278828257 0.792014312856256 0.428784014479218 -472.209452543951 131.931025144586 -3.57921460874308 0.000383423203956655 IMP3 essential 0.0321966573885473 1 1 0.792014312856256 -3.57921460874308 1.74363910005647e-22 29.3156532487511 35.9716817741208 0.814964766808364 0.41553538019113 -434.97223136291 54.9242485126483 -7.91949354141353 1.98271918644448e-14 ASB8 other 1.52167384261928e-18 1.92105661974606e-10 1 0.814964766808364 -7.91949354141353 0.439911613855412 -4.81243998599213 49.2193391551411 -0.0977753880608423 0.922155582986476 64.446760279105 72.2896705322112 0.891507179443963 0.373148860233758 ODF3B other 1 1 1 -0.0977753880608423 0.891507179443963 0.000172013065910208 56.9822417714969 24.3916853223694 2.33613385128575 0.019937643826965 -66.6468478980523 40.2461923676998 -1.65597896290782 0.0984472207274639 DPY19L2 other 0.82703882089628 1 1 2.33613385128575 -1.65597896290782 3.38340716708675e-08 72.5697262771978 52.4208626506896 1.38436726539148 0.166952518528073 -328.660750203241 84.0047532937273 -3.91240658792319 0.000105939580184232 LRRC75B other 0.000224218392962839 0.840630568761881 1 1.38436726539148 -3.91240658792319 1.68654606006276e-40 454.29806845611 77.2419619446007 5.88149312910955 8.07840858099018e-09 -249.928443783733 99.6635172375445 -2.50772249175229 0.0125119602723435 DMAP1 essential 1.57624594773465e-36 1 7.52907679748285e-05 5.88149312910955 -2.50772249175229 0.0227958483111438 115.704553841612 41.9008578025468 2.76138866623822 0.00599810335218105 89.5438039707729 47.2256778036831 1.8960829814451 0.0586084441367685 ADAMTSL1 other 1 1 1 2.76138866623822 1.8960829814451 1.37543695759832e-05 808.774643636819 418.98307236627 1.93032773154567 0.0542144644210015 -1570.86425452678 667.233696846676 -2.35429394820829 0.0190006176411631 IMPDH2 essential 0.0754152083851161 1 1 1.93032773154567 -2.35429394820829 0.114733276883269 -31.1915883259537 18.6717393242291 -1.6705239819559 0.0955317394239589 -59.0203798424375 29.3859332912771 -2.00845687824239 0.0452095211592045 ALS2CL other 1 1 1 -1.6705239819559 -2.00845687824239 0.161526926678596 109.286588174163 92.9753626386274 1.17543599801738 0.240463279654448 -189.707135181094 203.068219446113 -0.934203962089873 0.350716965817167 MLF1 other 1 1 1 1.17543599801738 -0.934203962089873 3.26672879478368e-07 64.8717349428528 88.7259239070716 0.731147471744528 0.46508182512425 -561.430602285858 141.296701750517 -3.97341618969391 8.28910796089327e-05 NDUFAF3 essential 0.00204203216961928 0.663708874428724 1 0.731147471744528 -3.97341618969391 0.891181799548399 -9.07672332389135 66.5092923745062 -0.136473010008607 0.891510064014291 44.1494334277613 128.773144285608 0.342846590200838 0.731878352571935 GRAMD1C other 1 1 1 -0.136473010008607 0.342846590200838 3.00490834014396e-05 29.5537476405515 6.51843536902618 4.53387139204951 7.48393387216195e-06 8.80206914677566 17.9816031848789 0.489504136882382 0.624729882309254 STAP2 other 0.159079847527221 1 0.0653197748362295 4.53387139204951 0.489504136882382 0.302183040918017 -1.27939317319836 3.36254264462925 -0.380483850589031 0.703771156353717 -7.84444467967981 5.45465176133605 -1.43812016291914 0.151115690670055 GOLGA8O other 1 1 1 -0.380483850589031 -1.43812016291914 4.36990748503663e-17 257.333238825184 45.282396339939 5.68285381571595 2.42014275209708e-08 -146.735453104594 74.7829400007637 -1.96215143591701 0.0503776172475861 NDUFV2 other 3.62134233284986e-13 1 0.000223717996003854 5.68285381571595 -1.96215143591701 1.99892396009236e-07 475.77717349428 155.366003807161 3.06229909913117 0.00233238785927679 -487.063060228585 247.421530657745 -1.96855568282105 0.0496371894102809 DALRD3 other 0.00126651822111452 1 1 3.06229909913117 -1.96855568282105 0.00119600073951562 -5.67186277056056 8.1952411056324 -0.69209223956357 0.489246127176638 -22.8912027835052 9.99978078985231 -2.28917045928997 0.0225445167329351 ZNF114 other 1 1 1 -0.69209223956357 -2.28917045928997 0.0125294991288502 133.29544258499 70.7827615614267 1.88316250517173 0.0603437687295328 -89.6090937796026 112.440179527795 -0.796949045758608 0.425914385688611 ZNF518B other 1 1 1 1.88316250517173 -0.796949045758608 1.09472841737501e-05 135.516716787546 42.3566357693272 3.19942116096202 0.00147754714625675 -86.3298078027189 68.9579801429479 -1.25191903277561 0.211270557851444 LCORL other 0.0605603760491854 1 1 3.19942116096202 -1.25191903277561 0.000125535503550028 42.8643084952165 15.2607087251973 2.8088019545542 0.00520868670471288 -10.7088309111333 22.933662690985 -0.466948130153794 0.64078322713581 PARD6G other 0.613994147863188 1 1 2.8088019545542 -0.466948130153794 0.00825881564935105 9.13808074168953 7.69100349299358 1.18815194272298 0.235418879695973 -29.1860276057695 14.7500302141387 -1.97870968276343 0.048476115916615 ZNF454 other 1 1 1 1.18815194272298 -1.97870968276343 0.951605316796351 -1.21454619216101 10.4164302309901 -0.116599080992986 0.907231330934052 1.11851292569154 13.2665549948026 0.0843107292081278 0.932847991133836 ZC3H12D other 1 1 1 -0.116599080992986 0.0843107292081278 2.18642280286817e-19 41.5567256541092 10.1442307550582 4.09658717920899 4.99560569938784e-05 -4.82952577404883 12.7216365089471 -0.379630857292003 0.704403446048113 VN1R1 other 1.85692888647594e-15 1 0.421129560458395 4.09658717920899 -0.379630857292003 5.2175672426813e-11 4623.8267579441 718.459630757131 6.43575026347881 3.24921091814719e-10 -1216.07284362138 2107.53220685208 -0.577012697441891 0.564229363741286 PLEC other 3.86986962389672e-07 1 3.07862734494446e-06 6.43575026347881 -0.577012697441891 0.980778880614523 0.565293825499382 6.31433191463848 0.0895255164190632 0.928705385251328 -0.860559349781592 9.81632220173149 -0.0876661678474448 0.930182259305564 RNF212 other 1 1 1 0.0895255164190632 -0.0876661678474448 2.12297520918281e-38 29.247385372562 8.05566930607248 3.63065864068115 0.000316109593685836 -32.3679623914128 10.1024216840726 -3.20398053096952 0.00145441822624468 ZNF543 other 1.97415464701909e-34 1 1 3.63065864068115 -3.20398053096952 0.016399692087894 -526.491582423374 346.410919287044 -1.51984695952125 0.129274262166068 -2006.20508093434 700.085166452138 -2.86565860422569 0.00436274278930591 TMEM151B other 1 1 1 -1.51984695952125 -2.86565860422569 1.36013766558172e-05 198.437660324931 115.336403010403 1.72051195585692 0.0860638855090009 -220.265471355275 134.910071550516 -1.63268367456761 0.103272696840005 SLITRK1 other 0.0745899495805018 1 1 1.72051195585692 -1.63268367456761 6.13910368156605e-08 750.231315012193 421.235687910748 1.78102505685879 0.0756044606644926 -2289.497399512 670.821004058942 -3.41297810542442 0.000702588221206535 WDR6 other 0.000400269560038106 1 1 1.78102505685879 -3.41297810542442 1.43829180203371e-07 104.481525761457 19.0536372830466 5.48354753527411 7.05675444700709e-08 -26.480852654185 14.883912027098 -1.77915944450446 0.0759070164274573 TMEM11 other 0.000918349315598523 1 0.00064738665296843 5.48354753527411 -1.77915944450446 0.000258732850587715 37.1769986508467 12.7868092004994 2.90744923678025 0.00382941579582742 -29.003960978309 24.5229146263698 -1.18272894638392 0.237559665754329 ZNF354B other 1 1 1 2.90744923678025 -1.18272894638392 0.0233198459897972 9.31412203085874 4.3413462060555 2.14544558042088 0.0324913390634007 1.28525960952831 6.52482974971125 0.196979792397678 0.843938863959339 KCNG2 other 1 1 1 2.14544558042088 0.196979792397678 0.371764827596056 4.30326924863043 6.06115948384952 0.709974594810921 0.47809856070448 13.872174236092 9.86720188087665 1.40588734309544 0.160468179097843 SHISA3 other 1 1 1 0.709974594810921 1.40588734309544 1.79855910337705e-17 163.830628406364 19.0815317243093 8.58582166114308 1.60909371552852e-16 -91.6537450698395 72.0257766956994 -1.27251310953669 0.203869057223454 ZFAND2A other 1.49640117400971e-13 1 1.56500454772304e-12 8.58582166114308 -1.27251310953669 1.97589329890157e-39 41.531347660589 8.9489778088775 4.6409040839714 4.59544895597177e-06 -29.9966601004191 11.1563207910001 -2.6887591942155 0.00744667263436809 ZNF223 other 1.84232291189582e-35 1 0.0404169735677717 4.6409040839714 -2.6887591942155 0.890577759755098 5.39293644626717 20.0068960963833 0.26955387883691 0.787630428270922 -4.70030777228703 30.5480221932534 -0.153866189521268 0.877786110412777 DNAJC22 other 1 1 1 0.26955387883691 -0.153866189521268 0.0146898430148663 150.325196166582 52.2094209782881 2.87927338303744 0.00418124279999058 130.516836416864 146.725303789428 0.889531887452583 0.374205584929405 CEP295NL other 1 1 1 2.87927338303744 0.889531887452583 9.52558542763591e-05 8.06225233655662 17.8105307908573 0.452667718398108 0.651013184210906 -59.063182338059 23.7115541675861 -2.49090303910989 0.0131129197727907 BEND3 other 0.473516851607781 1 1 0.452667718398108 -2.49090303910989 0.00281256673617886 -145.231682963779 55.9935204159981 -2.5937230216067 0.009812345449321 -258.727921429555 74.985644378994 -3.45036604769157 0.00061410241899616 NT5DC1 other 1 1 1 -2.5937230216067 -3.45036604769157 1.84916963186947e-08 516.39036171979 105.025167523954 4.91682492772043 1.24791620489623e-06 91.0611614605252 120.965364348387 0.752787063892634 0.451984131805786 GLDC other 0.000124634033188002 1 0.0111576187879772 4.91682492772043 0.752787063892634 0.0250393779774951 107.740198863636 47.7457171692956 2.25654163873199 0.0245300709401395 9.6340287642071 72.9562641511286 0.132052111992059 0.89500385019088 COX14 other 1 1 1 2.25654163873199 0.132052111992059 6.43503705862821e-09 158.057634519069 100.840624001371 1.56740040122045 0.117746581527452 -630.394619237186 160.589452850117 -3.92550449639773 0.00010055697260209 P4HTM other 4.43502754080656e-05 0.800031274022225 1 1.56740040122045 -3.92550449639773 3.94438038230759e-09 327.789400268251 157.499648134815 2.08120719093717 0.0380216444898584 -1060.94572906687 270.896342455923 -3.91642692348086 0.00010489964182957 DTX3 other 2.74016105158908e-05 0.832798256484957 1 2.08120719093717 -3.91642692348086 0.26865478671528 11.3119766779187 12.2439876373938 0.92388011266618 0.356057419635122 -28.499057472272 27.0326461802616 -1.05424593960325 0.292351530664788 KLHL11 other 1 1 1 0.92388011266618 -1.05424593960325 0.0247313422048588 16.0579375245397 51.9741895540883 0.308959844536462 0.75749999217917 -164.489482289179 82.7742693613937 -1.9872054873842 0.0475263573014965 SLC25A20 other 1 1 1 0.308959844536462 -1.9872054873842 2.30135904993949e-05 5.62191508447988 97.6433523480344 0.0575760146419538 0.954112612231647 -670.082352438618 170.641544585132 -3.9268418137432 9.99517617868033e-05 EPM2AIP1 other 0.123122709171763 0.795516072061168 1 0.0575760146419538 -3.9268418137432 0.857918675647794 -28.0159119382377 130.763565426442 -0.214248608523889 0.830452897384652 121.319195337064 301.798479747072 0.401987430283737 0.68788936057493 MAF other 1 1 1 -0.214248608523889 0.401987430283737 2.53984135894562e-19 39.9123458721112 69.0123874878861 0.578335967280035 0.563334551126055 -406.633192565365 88.2008709540901 -4.61030813150387 5.28331730647618e-06 CTNNBIP1 other 2.15632531374483e-15 0.0453202958549527 1 0.578335967280035 -4.61030813150387 0.392655609071751 -9.60731887629386 26.7986564592722 -0.358500019987748 0.720141879567117 -46.4305936020722 39.4272235518964 -1.17762777642604 0.239584506036781 OTOS other 1 1 1 -0.358500019987748 -1.17762777642604 0.039025964974123 21.0276714021002 9.12134764198527 2.30532507118909 0.021614918688646 11.9668622606548 13.3541710949065 0.896114193506119 0.370684006624213 GPR35 other 1 1 1 2.30532507118909 0.896114193506119 0.88669966599784 -4.81466049537445 91.7463512658609 -0.0524779506644642 0.958171843824281 -128.273300468869 269.149021243103 -0.476588396556006 0.633893458790611 PARP10 other 1 1 1 -0.0524779506644642 -0.476588396556006 7.77603468034065e-06 230.634973700796 49.5669593113933 4.65299822512581 4.34591396425125e-06 -18.5723458446514 101.996959489694 -0.182087249831481 0.855598882101251 SUZ12 og 0.0437168669728751 1 0.0382701183691965 4.65299822512581 -0.182087249831481 5.88779411814562e-07 9.76547129797141 9.43459364470705 1.03507068409353 0.301219006962009 -93.2315213093546 20.6083295693849 -4.52397274584818 7.86696918088293e-06 NSUN3 other 0.00363159141207222 0.0669479077293138 1 1.03507068409353 -4.52397274584818 0.159026135780034 -613.137251878256 650.999981698162 -0.941839123065504 0.346798962115067 -1359.19606706226 756.851727763376 -1.79585514203543 0.0732130012217345 KCTD12 other 1 1 1 -0.941839123065504 -1.79585514203543 0.000144160554734239 0.723212039154748 29.5359237312768 0.0244858446187315 0.980476459897688 -251.95179185488 64.5164034946913 -3.90523616022105 0.000109312847329322 DHFR2 other 0.700331974898933 0.866304315084878 1 0.0244858446187315 -3.90523616022105 0.114872623844981 -14.7151727431935 17.5751628944553 -0.83727091643833 0.40290005522079 -62.3651678152554 30.4947157870404 -2.04511392238517 0.0414448191883876 RPP25 other 1 1 1 -0.83727091643833 -2.04511392238517 2.68190337278041e-11 1877.37282758205 305.778285049435 6.13965385828015 1.8588224788852e-09 -1269.32040842965 897.037593353034 -1.41501361574498 0.157776680042535 GRINA other 2.00150448710602e-07 1 1.74785077689576e-05 6.13965385828015 -1.41501361574498 0.884815877543964 19.8939190787916 40.2097258630891 0.49475390970157 0.621023626896616 16.4786655098983 108.661557783949 0.151651290906971 0.879532282630803 THBD other 1 1 1 0.49475390970157 0.151651290906971 3.13045861351796e-08 36.1959879000185 87.0637824079353 0.415741045230761 0.677804513733638 -704.648751715299 151.064619760215 -4.66455185094822 4.12236371086875e-06 COX5A other 0.000208018974868269 0.035529114744459 1 0.415741045230761 -4.66455185094822 0.342500215283983 34.2400660227411 24.2904501178275 1.40961019069841 0.159369338710888 25.4145901005541 36.974005489801 0.687363723888787 0.492219855184553 ERFE other 1 1 1 1.40961019069841 0.687363723888787 1.46720212395358e-15 186.790638433373 87.1328097607051 2.14374629885528 0.0326070139017979 -846.116928605542 151.184389318932 -5.59658925380591 3.87508759806783e-08 FAM219B other 1.19048780337593e-11 0.000354841771355071 1 2.14374629885528 -5.59658925380591 0.630478773095534 -18.9204692486851 21.4265213841765 -0.88303971090043 0.377700318067525 -32.1476063141558 45.5288988912599 -0.706092330300724 0.48050697747419 CPNE7 other 1 1 1 -0.88303971090043 -0.706092330300724 5.72973103084146e-20 249.168126094574 110.781405970041 2.24918725225385 0.0250000734234816 -1273.06137936785 192.217136753306 -6.62303788762455 1.0405909121967e-10 MPI other 4.89319030033861e-16 9.83670589299536e-07 1 2.24918725225385 -6.62303788762455 0.000498359947081285 4.63305660377368 2.12476273593117 2.18050539263776 0.029752745045612 -4.55369182389929 3.37796978039592 -1.34805582048918 0.178338770936936 ADORA2A-AS1 other 1 1 1 2.18050539263776 -1.34805582048918 0.231485017726718 -34.3438318892376 23.3899369906383 -1.46831656292976 0.142737663049067 22.8869690063358 68.6172099610317 0.333545607863297 0.738882450856822 OPLAH other 1 1 1 -1.46831656292976 0.333545607863297 0.0631458279282283 5.49755012571729 4.13256339679008 1.33030025140992 0.184114762463842 20.195635355554 9.33209795695251 2.16410451848162 0.0309986155786975 EFCAB13 other 1 1 1 1.33030025140992 2.16410451848162 0.612712310045827 251.671441247306 310.371639625636 0.81087125599126 0.41788610098116 -310.639016351881 882.678608715216 -0.351927658929032 0.725064119037823 APOLD1 other 1 1 1 0.81087125599126 -0.351927658929032 0.0132178645808818 -12.9395556404341 14.7345831482727 -0.878175887992532 0.380329741169592 -80.7388973299666 27.3574859006521 -2.95125427910911 0.00333477434731764 RFLNA other 1 1 1 -0.878175887992532 -2.95125427910911 2.47302857526122e-36 416.087032509206 142.161186574476 2.92686803293686 0.003602609629593 -864.546738928953 183.810263937926 -4.70347368208403 3.43586960541228e-06 DPY19L3 other 2.2873041292591e-32 0.0296927851299729 1 2.92686803293686 -4.70347368208403 0.00527756199572672 556.568942133812 208.380269620692 2.67092917744524 0.00784649620049238 -331.804455038636 439.332107866069 -0.755247451979511 0.450507374554987 TAF7 other 1 1 1 2.67092917744524 -0.755247451979511 0.122998884896054 4.36165260401521 4.35130471300184 1.00237811224354 0.3167144493171 -5.54466104160604 6.8477380061941 -0.80970694798642 0.418548284634861 ZNF852 other 1 1 1 1.00237811224354 -0.80970694798642 5.60259349110535e-06 158.859893967619 63.5180443681511 2.50101991564579 0.0127477849258716 -218.66577729478 49.5145280906557 -4.4161943115852 1.2671498191435e-05 PFAS other 0.0319347828993005 0.106732029266457 1 2.50101991564579 -4.4161943115852 2.26014277015438e-30 77.9595216636108 46.7303253683858 1.66828544524435 0.0959737403508035 -321.965393819473 60.2950581603362 -5.33983055399506 1.49740733900137e-07 HYI other 2.04836739259092e-26 0.00135275779005384 1 1.66828544524435 -5.33983055399506 2.0608537978857e-14 662.563695279242 80.6259825298195 8.21774413768158 2.41408116808669e-15 459.957303513564 211.540232283304 2.17432541577987 0.0302202860110382 C17orf62 other 1.64147005001596e-10 1 2.3419001411609e-11 8.21774413768158 2.17432541577987 1.31235484934526e-37 11.0155859404592 3.66316593442858 3.00712174595429 0.00278950847593072 -17.3978595515032 4.57030139079798 -3.80672040284535 0.000160932409599908 ZNF552 other 1.2178653001924e-33 1 1 3.00712174595429 -3.80672040284535 1.3427826805463e-10 273.956619822975 95.7185410867338 2.86210609472969 0.00441291625870451 -499.97042875911 148.846065950045 -3.35897644031053 0.000851698008623859 GAK essential 9.85065374448763e-07 1 1 2.86210609472969 -3.35897644031053 0.60401073621189 -27.1816975960579 59.3063589631716 -0.458326865301871 0.646944939981575 -155.464688945889 156.539794811237 -0.993132060338749 0.321193927551394 ZBTB7A other 1 1 1 -0.458326865301871 -0.993132060338749 0.143922476361274 139.52155187599 80.0690974509998 1.74251435719471 0.0821219416984195 202.386554518229 102.864876268786 1.96749912953176 0.0497577317234554 ERICH3 other 1 1 1 1.74251435719471 1.96749912953176 8.49825365452011e-05 73.1279465821335 26.3697085977418 2.77317992768399 0.00578813762982707 -110.681797232433 56.6624503074513 -1.9533535283397 0.0514140071596358 RMI1 other 0.424232822433644 1 1 2.77317992768399 -1.9533535283397 0.0129539795723101 118.128643072074 42.9634170530759 2.74951694196346 0.00621527644217587 33.0443638894421 33.4914801251619 0.98664985142344 0.324359035032659 CTC1 other 1 1 1 2.74951694196346 0.98664985142344 1.49742846158031e-12 -52.3151010136972 70.3485539575622 -0.743655669813147 0.457486286340044 -468.411758421766 87.5737905332094 -5.34876651529817 1.43419092014811e-07 FBXO34 other 1.1485276300321e-08 0.00129622175362986 1 -0.743655669813147 -5.34876651529817 1.44458398729884e-06 3.2651955867603 2.90224077014495 1.12506020187885 0.26117965887899 11.521788742852 2.26239777324195 5.0927334172282 5.25343380377417e-07 LINC00324 other 0.00864150141202163 0.00467765745888052 1 1.12506020187885 5.0927334172282 1.70785637568916e-19 1702.27050305565 512.592555094803 3.32090368097683 0.000972373314458747 -809.448168819496 625.46215778026 -1.29416010025642 0.196292060383422 SELENOW other 1.45167791933579e-15 1 1 3.32090368097683 -1.29416010025642 2.834278618211e-38 1001.52114118278 120.680171250721 8.29897016886106 1.31294566761167e-15 4.28292321749199 166.321382026057 0.0257508876208172 0.979467762674933 EIF3K other 2.63474540348895e-34 1 1.27421377041712e-11 8.29897016886106 0.0257508876208172 1.57106382358381e-13 -42.5648690983623 100.179001767873 -0.424888133712794 0.671127349469483 -1070.86558816352 159.126849399905 -6.72963483033779 5.35520273256821e-11 MRFAP1L1 other 1.23281378236622e-09 5.07887427156769e-07 1 -0.424888133712794 -6.72963483033779 1.93989605530657e-06 166.057286144148 32.8531198977722 5.05453627116274 6.3505373364561e-07 26.4965199866762 25.6101513235438 1.03461005176949 0.301421943199387 AURKB essential 0.0114958240237467 1 0.00572373930134788 5.05453627116274 1.03461005176949 7.83546203304085e-06 44.5796821968529 9.86513209863934 4.51891386259305 8.00711707215165e-06 54.860922554767 11.3328215867373 4.84088822319151 1.79497484205919e-06 C14orf39 other 0.0440274611636566 0.0156898750944394 0.0698060466350181 4.51891386259305 4.84088822319151 4.67469984302145e-12 407.347227451214 569.801696043994 0.714892971150025 0.475056038575069 -5108.56682339418 905.030812426978 -5.64463303707283 2.97858747188325e-08 MRFAP1 other 3.55043453077479e-08 0.000273166257046413 1 0.714892971150025 -5.64463303707283 0.0145745786194711 50.0743089906776 29.8079875207829 1.67989566406536 0.0937039392370773 -69.2442389901503 50.7150899386146 -1.36535770860238 0.172854491553431 C3orf38 other 1 1 1 1.67989566406536 -1.36535770860238 0.000117284218064299 39.0874623871616 19.3125046366336 2.0239457865562 0.0435822942995248 55.7532024645367 15.0547700711483 3.70335795239974 0.000239946989333668 TMEM107 other 0.576569216004095 1 1 2.0239457865562 3.70335795239974 0.852727555581288 5.32368726117423 9.57560647091469 0.555963455405629 0.578520371716715 6.37219669972697 22.1005912167577 0.288326979003859 0.773233161223067 EXOC3L1 other 1 1 1 0.555963455405629 0.288326979003859 1.37004932792907e-52 742.309706579913 167.99044776466 4.41876140255205 1.25283069363336e-05 -1169.88062474977 214.661199905398 -5.44989325162318 8.42851475896735e-08 RCC2 other 1.31401431041677e-48 0.000766489132180491 0.108432496533967 4.41876140255205 -5.44989325162318 5.58365324866918e-07 5.64970117189376 5.43691767960588 1.0391367875747 0.299317037129256 -22.8329567461153 6.82947575306198 -3.34329567476364 0.000899336353126313 IGSF22 other 0.00344846424637809 1 1 1.0391367875747 -3.34329567476364 0.00346267582498565 15.3630816375905 4.81482735964318 3.19078556509844 0.00152113429424516 1.66506814332965 10.4476119503884 0.159373084608846 0.873448574876402 C9orf50 other 1 1 1 3.19078556509844 0.159373084608846 0.357951483062175 0.311906923013426 4.44061354503492 0.0702396008682564 0.944035012684629 -4.63854278405814 5.67343469523258 -0.81758987865956 0.414035927679964 TAAR3P other 1 1 1 0.0702396008682564 -0.81758987865956 6.63985260945508e-20 749.908996897621 81.9577399934403 9.14994724058573 2.18876757156727e-18 -105.514994829371 240.432945813937 -0.438854144851785 0.660984116781471 CYC1 essential 5.66379427586518e-16 1 2.13492388930671e-14 9.14994724058573 -0.438854144851785 0.742650483674237 -50.3536094462828 134.40756346945 -0.374633749370272 0.708114185348659 -163.629752213972 214.019475420087 -0.764555430727937 0.444948022064512 TMTC2 other 1 1 1 -0.374633749370272 -0.764555430727937 0.00097424224931951 3.45473563547791 3.52153371780437 0.981031536915651 0.327118753118627 9.82276849100182 2.74515819759473 3.57821581998749 0.000384573093045512 HES7 other 1 1 1 0.981031536915651 3.57821581998749 9.63428521223795e-05 69.1906898997701 24.0800781269191 2.87335819822037 0.00425929920863158 -16.0972699074923 30.1917571244243 -0.533167706707275 0.594188532390702 SPTY2D1 other 0.478438603639737 1 1 2.87335819822037 -0.533167706707275 1.341387572569e-61 486.805896449669 97.7463173922822 4.98029909910556 9.15019267383913e-07 -995.378379403561 138.286203930948 -7.19795866188209 2.67570570814601e-12 SAMD4B other 1.30074352912016e-57 2.56519906239958e-08 0.00821687302110754 4.98029909910556 -7.19795866188209 0.000123544098529329 90.3833215478237 66.1409666299865 1.36652556128272 0.172478351087701 -292.209378745996 114.755872339524 -2.54635665076421 0.0112282854533819 EDC3 other 0.604995450498123 1 1 1.36652556128272 -2.54635665076421 1.18395477258693e-08 71.3078265929603 56.0943522998358 1.27121222849326 0.204327823515644 -354.365235900341 88.2768395944935 -4.01424923601871 7.01481480151156e-05 TCAIM other 8.05799618222668e-05 0.56469259152168 1 1.27121222849326 -4.01424923601871 8.48073565683854e-14 -18.0688559406759 44.9767520350702 -0.401737678314052 0.688073487877677 -264.922950054872 57.4940058538296 -4.60783600169384 5.34678861784703e-06 FUCA1 other 6.68451584472014e-10 0.0458433656094204 1 -0.401737678314052 -4.60783600169384 0.0046505546724208 12.024498488075 3.84690615418049 3.12575820832224 0.00189147448378132 16.9048737789028 5.34772620013378 3.16113300237396 0.00168066288467457 GGN other 1 1 1 3.12575820832224 3.16113300237396 0.00167106303092127 -1.00048603834264 3.45612261346783 -0.289482217570623 0.772350307323126 -10.0061455017563 4.54849115523598 -2.19988236983549 0.0283404565905381 HNRNPCL1 other 1 1 1 -0.289482217570623 -2.19988236983549 0.235170119723277 44.6374342219552 63.1267738867312 0.70710780028215 0.479875516520563 115.763502594274 81.0656716381906 1.42802126047811 0.153998363077654 TMEM125 other 1 1 1 0.70710780028215 1.42802126047811 2.62011976496555e-06 638.969230164323 270.884348384135 2.35882668738843 0.0187710793142363 -1736.8541325552 502.947023818252 -3.45335403194043 0.000607519339196653 ZNF664 other 0.0153905834994076 1 1 2.35882668738843 -3.45335403194043 0.025364523063623 500.203377464314 208.908245099706 2.39436876809521 0.0170704489508239 143.015018877363 262.4369602189 0.544949990116 0.586066546521304 LDLRAD3 other 1 1 1 2.39436876809521 0.544949990116 2.14834341806574e-05 -325.528437398552 452.2765117225 -0.719755346477696 0.472059519074905 -3438.91082524436 801.211673979591 -4.29213769210751 2.18019139909964e-05 PTPN11 essential 0.115301591247589 0.181274594842615 1 -0.719755346477696 -4.29213769210751 0.536016814660503 13.9146288407509 12.4961980335577 1.11350898916487 0.266101981710794 10.95979938971 20.5327868377544 0.533770670114679 0.593771602041261 NSUN7 other 1 1 1 1.11350898916487 0.533770670114679 5.34611085997647e-08 79.1446819613633 61.2800556258928 1.29152431656609 0.197206179880707 -422.890844737547 106.322096556352 -3.97745020493845 8.15463795820837e-05 CLK3 other 0.000349853949297969 0.65318650045249 1 1.29152431656609 -3.97745020493845 0.0229986327519996 696.960504201689 276.125175755172 2.52407446114096 0.0119528181892884 1284.66457659987 643.602083978435 1.99605409705745 0.0465467191045934 HLA-DQB1 other 1 1 1 2.52407446114096 1.99605409705745 0.605355222994602 27.6135392251483 34.3604793420194 0.803642433223557 0.422041425670073 -13.5783715112961 70.2037070860644 -0.193413881900141 0.846724914418772 GATA2 other 1 1 1 0.803642433223557 -0.193413881900141 1.62476976443903e-05 13.0811876770193 8.79279248066932 1.48771709394687 0.137548367554056 -43.4721893446372 15.2556671429436 -2.84957641886838 0.00458518685232509 ARID3B other 0.088452465976061 1 1 1.48771709394687 -2.84957641886838 1.24520227562982e-12 332.168022963349 386.741650938216 0.858888671953296 0.390872807364988 -1871.00785665669 449.05563395413 -4.16653909935759 3.72875208742881e-05 PACS2 other 9.57311509504206e-09 0.306279696461402 1 0.858888671953296 -4.16653909935759 2.10899903741002e-12 147.666788614304 33.0888192747555 4.46273973659022 1.03030960471906e-05 -64.7141153835271 44.8034664839664 -1.44439974095947 0.149341511813028 ELMOD2 other 1.6135951635224e-08 1 0.0894411767856613 4.46273973659022 -1.44439974095947 0.000175816897796778 10.2993466503493 2.76387249133981 3.72641888604514 0.000219830784674416 -4.49658521179586 5.79154150837939 -0.776405591722006 0.437931490653084 CATSPERE other 0.844096926322329 1 1 3.72641888604514 -0.776405591722006 0.22506971872319 -107.824353067839 67.5393116554529 -1.59646804838488 0.111110506891485 -139.898469070675 88.7495357717572 -1.57632902362961 0.115676931147129 GPC5 other 1 1 1 -1.59646804838488 -1.57632902362961 0.0284538160170113 -13.0908248331544 181.484721368232 -0.0721318286986438 0.942529997354205 -382.06088740888 240.818645087134 -1.58650874923177 0.113347234629174 VWA1 other 1 1 1 -0.0721318286986438 -1.58650874923177 0.0313819804004626 89.8546456210107 34.0186661434448 2.64133359145021 0.00855615883311769 -2.34754782188615 24.1953414622472 -0.0970247857650247 0.922751500161088 GEMIN4 essential 1 1 1 2.64133359145021 -0.0970247857650247 0.000580846231488245 600.195351000386 189.701288449334 3.16389707158309 0.00166539309670175 75.7954664693346 237.819486398841 0.318710075515931 0.750098644620921 FJX1 other 1 1 1 3.16389707158309 0.318710075515931 6.27498109767287e-11 3.92639284261722 65.8204910926858 0.0596530469073563 0.95245955320943 -429.554885115901 87.9105817735996 -4.88627053136965 1.45055394030321e-06 KLHL28 other 4.64160351794862e-07 0.0127213580564591 1 0.0596530469073563 -4.88627053136965 0.034910728927689 20.5309758043074 49.1256403744543 0.417927901759907 0.676206528059418 -157.000272883752 84.6728291190209 -1.85419897406597 0.0643888886524321 MKRN3 other 1 1 1 0.417927901759907 -1.85419897406597 0.357217423680553 83.2286674430534 191.295735222414 0.435078530874125 0.663721199016515 -474.856026212945 400.849603007373 -1.18462391542947 0.236813001850766 ZBTB18 other 1 1 1 0.435078530874125 -1.18462391542947 4.56773831415006e-15 7.28893859292382 6.34077949536301 1.14953352316607 0.250972055467243 -42.6292700284668 8.46881579097509 -5.03367543711309 7.07603450425576e-07 C14orf28 other 3.67657256905939e-11 0.00627290458802273 1 1.14953352316607 -5.03367543711309 1.07045786460614e-06 -4.92107751826911 5.27213566118939 -0.933412536118032 0.351121273976543 -21.3716336393226 4.10981339067491 -5.20014696721132 3.06259720288596e-07 ALOX12B other 0.00647305870727335 0.00274653717154813 1 -0.933412536118032 -5.20014696721132 0.406294511551214 -142.708169405979 181.270295885176 -0.787267261351943 0.431552193750536 -422.859405331957 315.131659604339 -1.34184996157756 0.180341446210694 SLC17A8 other 1 1 1 -0.787267261351943 -1.34184996157756 3.41671535619457e-24 512.910491444592 47.466825445826 10.8056624100547 2.78523208799968e-24 208.265437857854 135.906782576402 1.53241386419235 0.126143929250291 SHARPIN other 3.00978455727179e-20 1 2.73231267832769e-20 10.8056624100547 1.53241386419235 4.80763607800666e-06 88.5570395155244 47.4810558954954 1.86510257291742 0.0628354866990197 -103.314390130048 57.3710338630195 -1.80081102210437 0.0724204330647674 DNHD1 other 0.0276006387238362 1 1 1.86510257291742 -1.80081102210437 0.0213888610952417 -2.36326261906994 5.93020102064874 -0.398513070778064 0.690447557667966 -13.6894640673912 7.58699821818598 -1.80433205250762 0.0718708092555525 HTR1D other 1 1 1 -0.398513070778064 -1.80433205250762 6.2770883911315e-07 63.446879527574 14.9823274376352 4.23478126423782 2.79344033309707e-05 -3.32311821055005 22.6756435646639 -0.146550116695632 0.883555020953134 LSMEM2 other 0.00386480332241966 1 0.238224591606518 4.23478126423782 -0.146550116695632 0.466483957623368 10.6105909888826 12.966668742665 0.818297374557736 0.413632359325246 -14.1220986931927 27.5518582755213 -0.512564290654022 0.608514516607188 ZFPM1 other 1 1 1 0.818297374557736 -0.512564290654022 0.273071501245515 -17.3516549648945 42.4518304014444 -0.408737498496747 0.682932079624411 52.1850642837606 33.0926805102651 1.57693675698386 0.115532019653239 ALOX15B other 1 1 1 -0.408737498496747 1.57693675698386 0.1263828156475 11.8960611667844 24.7292512726148 0.481052217701315 0.630719601699057 35.7621782610505 18.3542141499873 1.9484450801766 0.051999962892582 PLD6 other 1 1 1 0.481052217701315 1.9484450801766 0.355059648667641 36.9257795360107 38.5353512480542 0.95823129516369 0.338484590618816 3.21988885373211 45.1138111147918 0.0713725746986687 0.943134419212441 ZBTB42 other 1 1 1 0.95823129516369 0.0713725746986687 0.638199783503905 -30.7603781393071 37.0985528086696 -0.82915304804339 0.407470469869651 -41.511186405608 44.4700408424088 -0.933464094461115 0.351095870782395 LACC1 other 1 1 1 -0.82915304804339 -0.933464094461115 3.15913037508734e-41 1144.79290609179 77.3826610251318 14.793920122752 1.94880384718971e-40 381.227576686094 221.561656764447 1.72063877050439 0.0860242552014931 MAF1 other 2.95820968323178e-37 1 1.91918202871242e-36 14.793920122752 1.72063877050439 7.14949466732854e-06 9.18733037256381 16.5853387293396 0.553942884284378 0.57990062048118 -72.165741426104 22.9234631542085 -3.14811688533437 0.00175557121626709 TPPP2 other 0.040301701439731 1 1 0.553942884284378 -3.14811688533437 0.296229876211745 -12.0438797943357 8.20400472513054 -1.46804886124003 0.142811981473675 -14.526517398071 19.2094935240624 -0.75621553373464 0.449928370509534 RPRML other 1 1 1 -1.46804886124003 -0.75621553373464 0.000355372582220772 23.3273242625018 7.05057806542416 3.30856903448788 0.00101531085902747 -19.769728585433 20.1871806503928 -0.979320932814276 0.327963268220053 WDR97 other 1 1 1 3.30856903448788 -0.979320932814276 5.91460015927391e-07 17.3959270907538 18.696038885971 0.930460574929978 0.352648739376983 140.167746867995 28.8430391610935 4.85967328495215 1.64434295095512e-06 PCED1B other 0.00364635099819236 0.0143962225356121 1 0.930460574929978 4.85967328495215 0.797915461623092 1.538201917433 5.85249633270118 0.262828343665626 0.792806470675291 5.95089023674424 9.15945165452452 0.64969939917797 0.516226987362512 APOBEC3B other 1 1 1 0.262828343665626 0.64969939917797 0.675378860261709 -146.832358725694 175.614456643546 -0.836106329353783 0.403553069532037 35.25683210905 383.947546589526 0.0918272103109509 0.92687749968821 PIPOX other 1 1 1 -0.836106329353783 0.0918272103109509 0.887774658678377 1.76565917119946 3.7804356181743 0.467051776443732 0.640697221510803 0.554456291572829 4.41707793568149 0.125525584933399 0.900165596508204 ATP8B5P other 1 1 1 0.467051776443732 0.125525584933399 0.228272020922791 -0.484352974344461 4.71573130126072 -0.102710045039032 0.918240107797379 -6.32467261252142 5.72579666901407 -1.10459259700021 0.269942584794816 ATOH7 other 1 1 1 -0.102710045039032 -1.10459259700021 0.20890185013896 -116.222809966912 68.4888337871598 -1.69695997931711 0.0904146514776114 -170.638526307521 158.070222765852 -1.07951088650192 0.280954129356205 CDH5 other 1 1 1 -1.69695997931711 -1.07951088650192 0.748785180890725 -32.8159063475081 43.8149923757681 -0.748965241533556 0.4542801773792 -19.1238754640497 86.938215475503 -0.219970876552422 0.825996320546118 LRRC3B other 1 1 1 -0.748965241533556 -0.219970876552422 2.60061322975894e-06 338.54085441725 120.205063813445 2.8163610057448 0.00507858279128704 79.9663130243645 148.353112466518 0.539026864316125 0.590144708244504 MYADM other 0.0152812033380635 1 1 2.8163610057448 0.539026864316125 0.00122675359146189 116.721158103795 36.791994856433 3.17246070943572 0.00161838166166783 -68.4123783056749 105.33940344673 -0.649447178047395 0.516391359513379 MROH1 other 1 1 1 3.17246070943572 -0.649447178047395 0.0668663220047882 -56.1187048462809 72.8799366962946 -0.770015828637981 0.441705597242098 -149.154255279079 82.8703979392369 -1.79984963253638 0.0725724061471693 AKAP5 other 1 1 1 -0.770015828637981 -1.79984963253638 0.000259553597331097 -7.77712992457625 4.28242097023949 -1.81605918208955 0.0700479575895368 -17.8087693841066 5.31473142430084 -3.35083148372815 0.000875819175567414 NKPD1 other 1 1 1 -1.81605918208955 -3.35083148372815 0.533172199646074 13.4295286602929 12.971422977781 1.03531653260376 0.301092372143194 -2.50519767878775 35.8676608694299 -0.0698455828471084 0.944348442651315 GIPC3 other 1 1 1 1.03531653260376 -0.0698455828471084 4.73351942071076e-06 5.45972076243742 20.6489888379812 0.264406204355873 0.791591300524517 -65.3515491069629 26.5168651229347 -2.46452771864196 0.0141022856445036 CITED4 other 0.0271846020331419 1 1 0.264406204355873 -2.46452771864196 1.19302330370863e-29 295.41898284039 24.5409555476821 12.0377946272876 4.97301263260955e-29 71.341333390077 71.996508211681 0.990899908372255 0.322281541155262 TIGD5 other 1.07825446189186e-25 1 4.88847141785519e-25 12.0377946272876 0.990899908372255 1.02417380766151e-05 135.448244914241 52.8292959172323 2.56388510508352 0.0106834121523414 -14.1949120241102 70.2620546290782 -0.202028137364426 0.839988526776928 C1orf194 other 0.0568416463252136 1 1 2.56388510508352 -0.202028137364426 2.80328578729559e-12 -46.1005411580084 36.3246053488648 -1.26912710310971 0.205071254457257 -205.442053400408 45.5604930503801 -4.50921488433485 8.369597073981e-06 ZNF154 other 2.13890705570654e-08 0.0711666839200605 1 -1.26912710310971 -4.50921488433485 1.02082762019352e-09 84.700681735668 108.76433028556 0.778754224967755 0.436551847739729 -945.925950328763 187.447255700291 -5.04635795704153 6.65257332078543e-07 R3HDM2 other 7.26523017291731e-06 0.00590216305020084 1 0.778754224967755 -5.04635795704153 1.02213238789443e-32 78.149333915702 12.2636105125525 6.37245726580373 4.7465820388234e-10 5.97826308509882 15.1733934797018 0.393996444704096 0.693776728558463 ZNF784 other 9.34842281968247e-29 1 4.48741865950364e-06 6.37245726580373 0.393996444704096 3.14710440146307e-09 137.369483738361 34.4473743651833 3.98780709037736 7.81603125547741e-05 -67.0078587837034 51.7216908752408 -1.29554656179619 0.195815666367134 C14orf119 other 2.19604945134093e-05 1 0.653342052645357 3.98780709037736 -1.29554656179619 2.66045063389021e-06 18.8551912568293 55.4608139503052 0.339973215570262 0.734039672441642 -357.714103564923 90.2817326537891 -3.96219803331288 8.66818536019931e-05 BBS10 other 0.0156062034184 0.693281465108741 1 0.339973215570262 -3.96219803331288 6.35029875854038e-46 167.846551320335 29.2107225121984 5.74605955913079 1.72205320714688e-08 -66.7913519526897 36.1659402594932 -1.84680258479268 0.0654563072951903 FIZ1 other 6.01436795421359e-42 1 0.000159668773366659 5.74605955913079 -1.84680258479268 6.21444126895176e-33 2524.01567579503 202.4135523086 12.4695982408674 9.42378864203989e-31 48.3452512673447 579.567323552141 0.0834161094021639 0.933558789048009 PUF60 essential 5.68932098172534e-29 1 9.26546899285362e-27 12.4695982408674 0.0834161094021639 2.28125867703608e-08 135.512054277182 40.012338252765 3.38675669042706 0.000771671381942739 36.2354060542191 49.5394742217633 0.731445107632984 0.464902061647915 SSC5D other 0.000152935581708499 1 1 3.38675669042706 0.731445107632984 1.72972792537585e-05 22.7833018985556 143.230643971083 0.159067230774689 0.873689900280688 -712.977491643232 213.505508521369 -3.33938686913024 0.000912105440140738 TSHZ1 other 0.0939069290686551 1 1 0.159067230774689 -3.33938686913024 1.74765926240842e-32 19.0406008846468 11.7278801566337 1.62353303669094 0.10519494197112 -72.9468366991459 13.6148023277355 -5.3579064126801 1.36343643525833e-07 PSTK other 1.5973605658413e-28 0.00123377363026526 1 1.62353303669094 -5.3579064126801 2.15211804182674e-10 90.8315741993693 64.9251705517474 1.39901941615962 0.162519767353462 -253.073748308526 80.8224613921922 -3.13123040240611 0.00185816346727629 SOCS4 other 1.56674193444986e-06 1 1 1.39901941615962 -3.13123040240611 1.55188024327878e-09 25.5361849592021 65.9721079612156 0.387075473989926 0.698890066839675 -439.613738152586 98.3407465606993 -4.47031117341824 9.98208737561925e-06 ZADH2 other 1.09640339187645e-05 0.0845782263336219 1 0.387075473989926 -4.47031117341824 0.608323156134993 -18.5047683703487 19.1467509847219 -0.966470415012681 0.334345847192461 -25.7739307535643 43.5208167889969 -0.592220749866085 0.554010466229928 C3orf80 other 1 1 1 -0.966470415012681 -0.592220749866085 0.91975532064095 -0.16323848228256 5.61148798067489 -0.0290900529137242 0.976806171833913 -2.40850033614596 6.56553199136364 -0.366840088406259 0.713917503295608 ANKRD18A other 1 1 1 -0.0290900529137242 -0.366840088406259 2.41407211744508e-34 35.1135799249893 12.1263819083517 2.89563533380108 0.00397502025675336 -52.3814961215182 15.0054902961983 -3.49082203163926 0.000530838545803756 TMEM86B other 2.21829086872029e-30 1 1 2.89563533380108 -3.49082203163926 4.69287012366162e-70 116.391336492195 16.586851152592 7.01708452203763 8.6600961733842e-12 -107.304057348898 21.2980730694327 -5.03820495868721 6.88447636581847e-07 TRNAU1AP other 4.58117981471848e-66 0.0061058420888444 8.30070218218875e-08 7.01708452203763 -5.03820495868721 2.82242035393395e-20 172.547405163653 86.2703629347747 2.00007742281215 0.046114561649192 -863.198035973228 132.656717682601 -6.50700583470297 2.11786834282564e-10 EXOC3 essential 2.41740303314443e-16 1.998208781456e-06 1 2.00007742281215 -6.50700583470297 0.247900775673093 -6.54468141165439 5.56781143752928 -1.17544954334132 0.240454928316816 -19.9849378631965 12.8824620950802 -1.55132906393947 0.12154672646468 TDRD6 other 1 1 1 -1.17544954334132 -1.55132906393947 0.301587911345488 2.38501013331357 2.60906620167955 0.914124038622805 0.361155754516874 -0.295443860380697 3.13611860300715 -0.0942068517744842 0.92498802039393 CSNK1A1L other 1 1 1 0.914124038622805 -0.0942068517744842 0.201609778009857 -92.8481146512098 205.456617534281 -0.451911044606377 0.651557282385355 151.459364271512 248.468165719812 0.609572513375042 0.542461824750358 ACTA2-AS1 other 1 1 1 -0.451911044606377 0.609572513375042 0.710089366934484 -163.987158631952 204.032621131559 -0.80373009826803 0.42198983658661 -278.754665143443 648.604477437592 -0.42977604201054 0.667570397347911 LYNX1 other 1 1 1 -0.80373009826803 -0.42977604201054 1.74249630230786e-36 196.79763155273 53.853711804397 3.65430023222025 0.000289148016196425 -291.523175862148 69.1499717769504 -4.21581048221513 3.02488552795623e-05 RCC1 essential 1.61268032778592e-32 0.249916042319743 1 3.65430023222025 -4.21581048221513 0.408063436753948 -84.5889015837983 97.0029049528177 -0.87202441643312 0.383682828892858 62.8550626428187 173.031454354624 0.36325801500806 0.716591079088565 HERC2P3 other 1 1 1 -0.87202441643312 0.36325801500806 6.29340528885543e-43 10.8455552218041 4.47637545582791 2.42284306328326 0.0158088438681971 -48.1732993170391 6.68788302808672 -7.20307145246537 2.62885862771007e-12 ZNF816 other 5.92020635522631e-39 2.52054965224841e-08 1 2.42284306328326 -7.20307145246537 0.059528140481382 -39.1343669250646 27.7540664599985 -1.41004083064615 0.159237332595201 -109.654158976253 46.0239636457785 -2.38254488075389 0.017619180085413 FGD6 other 1 1 1 -1.41004083064615 -2.38254488075389 0.580793401486535 -25.4397973833192 69.9964836474407 -0.363443934004668 0.716449845625172 -148.259916389016 142.210714837335 -1.04253689012533 0.297741873817111 PLD5 other 1 1 1 -0.363443934004668 -1.04253689012533 1.05669237809572e-17 68.1766080989375 136.902794129786 0.497992816964022 0.618740192022615 -1684.71082407778 233.720630603165 -7.20822470712162 2.51732122315708e-12 OAZ2 other 8.81387112569639e-14 2.41385932088533e-08 1 0.497992816964022 -7.20822470712162 4.39756062418724e-11 93.9448744672131 18.9678108494657 4.95285804001253 1.04609741016603e-06 -163.838455006073 42.914294020567 -3.81780613535323 0.00015404925447229 CCDC43 other 3.26782729983353e-07 1 0.00937303279508767 4.95285804001253 -3.81780613535323 0.595897144966866 -0.770551849730759 35.369172437062 -0.021785973395389 0.982628604282049 -27.9557854714478 42.3913592774904 -0.659468956596826 0.50994125489347 KCTD4 other 1 1 1 -0.021785973395389 -0.659468956596826 2.77132282122672e-06 19.6610675670736 5.34206414463811 3.68042521294089 0.000261874787986718 -31.9396126138203 12.0863136605027 -2.64262648736289 0.00852134773251499 MEIOC other 0.0162260951182825 1 1 3.68042521294089 -2.64262648736289 0.00722061478267275 -2.27817123168016 16.1202784533161 -0.141323317601348 0.887679504530972 110.838544396633 36.4718087252808 3.03901967767791 0.00251560629722806 FZD2 other 1 1 1 -0.141323317601348 3.03901967767791 9.72561486600651e-08 30.1280445591288 14.6674802194335 2.05407091800342 0.0405618058185254 -55.3143369626788 21.3236063504206 -2.59404230474305 0.00980337839515667 TIGD2 other 0.000628080208046701 1 1 2.05407091800342 -2.59404230474305 0.627369494095376 138.847202549573 270.633075147213 0.513045947817155 0.608177839190139 -253.233331647112 523.99102125688 -0.483277997855172 0.629139847728609 HCLS1 other 1 1 1 0.513045947817155 -0.483277997855172 0.000181782292473476 113.850840811403 167.959971090014 0.67784508459094 0.49822947433041 -849.095884458912 286.741484049132 -2.96118954421476 0.00323189763877845 ZNF609 other 0.870918963240422 1 1 0.67784508459094 -2.96118954421476 1.89602584175747e-11 620.918799547003 166.735377127177 3.72397754001178 0.000221963768867695 -846.259613964252 283.508949834684 -2.9849484979494 0.00299657403258138 PAK2 other 1.42028004552212e-07 1 1 3.72397754001178 -2.9849484979494 0.000663451005323994 46.0058448646177 28.6066008537185 1.60822479748192 0.108509796918405 -99.928371066747 47.192763118568 -2.11745116122328 0.0347871043665056 CCDC66 other 1 1 1 1.60822479748192 -2.11745116122328 0.384093594287257 0.322533460103732 38.3427577289885 0.00841184826567353 0.99329226941363 42.5103854311413 46.9012117276589 0.906381388992382 0.365238115685078 ATP5EP2 other 1 1 1 0.00841184826567353 0.906381388992382 1.25492108661726e-07 44.1491007177285 15.4330368239347 2.8606878361917 0.00443185005970925 -49.6496713163383 20.2175155232057 -2.45577510546982 0.0144500266265535 HARBI1 other 0.000803274987543705 1 1 2.8606878361917 -2.45577510546982 0.817407736856863 -12.1046148411226 27.462166109729 -0.440774219803235 0.659594424236578 -20.8337711597682 33.0097450038455 -0.631140021146516 0.528278936536185 SERTM1 other 1 1 1 -0.440774219803235 -0.631140021146516 9.22167461779292e-05 507.754310344828 117.76045592226 4.31175564299807 2.00356976995602e-05 591.408891142668 253.045594677072 2.33716335547119 0.0198814409660081 GAS1 other 0.459147179219909 1 0.171833237325164 4.31175564299807 2.33716335547119 3.60041743543772e-59 50.1418108703935 7.67530276447725 6.53287725696754 1.79799375133444e-10 -43.1821311808972 10.2305815674236 -4.22088723855137 2.96145779334133e-05 ZNF571 other 3.48088357658119e-55 0.244882944931394 1.70701526751692e-06 6.53287725696754 -4.22088723855137 0.0212607742949696 -10.8743169398909 14.4735950856488 -0.751321069543617 0.452862937432328 -61.6469685141817 23.5608017443197 -2.61650554947877 0.00919059938666161 GLIPR1L2 other 1 1 1 -0.751321069543617 -2.61650554947877 0.0167880654725371 -41.4310153024433 57.7253307794832 -0.717726771644049 0.473308389849257 -155.416091867298 74.1292865460234 -2.09655453476957 0.0366060686540804 MIGA1 other 1 1 1 -0.717726771644049 -2.09655453476957 0.312981104821643 39.7429563874945 81.4071531920461 0.488199805903268 0.625696731193745 -165.18529174415 144.449185985313 -1.14355294297709 0.253546421637767 NRIP1 other 1 1 1 0.488199805903268 -1.14355294297709 0.0226893152397592 248.583400959432 89.9478165699597 2.76364019093325 0.00595871513501326 227.301133036804 168.483676330268 1.34909884439629 0.178007026066367 RNF182 other 1 1 1 2.76364019093325 1.34909884439629 0.00989359059743251 214.05765430338 82.7312922286531 2.587384392737 0.00999411977455999 435.622928275282 168.361737458045 2.58742238499312 0.00999303480904984 HIST1H2AC other 1 1 1 2.587384392737 2.58742238499312 3.4230539734176e-17 8.11360478335926 4.46659098818177 1.81650945986037 0.0699772211333427 72.954627754661 8.75958151312536 8.32855172879501 1.06417048698194e-15 SKIDA1 other 2.8394232709499e-13 1.03575713497952e-11 1 1.81650945986037 8.32855172879501 6.42286531921901e-07 -0.046400265391553 3.21553918153729 -0.0144300108852568 0.988493517212542 31.0869974927224 6.41599712210329 4.8452324558605 1.76066854503697e-06 HIST1H2BC other 0.00394731302802805 0.0154023284319835 1 -0.0144300108852568 4.8452324558605 0.00209041240470374 5.54255028047568 41.3169903598798 0.134146999386908 0.893348376974549 -234.27561909974 78.2146875157231 -2.99528933172104 0.00289846444237117 MB21D2 other 1 1 1 0.134146999386908 -2.99528933172104 0.321705782349081 11.9380040750487 16.2133247507929 0.736308206894142 0.461958145776827 42.1108116138889 27.9491439549026 1.50669414712082 0.13264803480461 GSX2 other 1 1 1 0.736308206894142 1.50669414712082 0.699758409129703 22.4743652647435 27.2064341383475 0.826068023117587 0.409215238996448 -4.54976469531321 19.8270580417341 -0.229472505993394 0.81860880498795 ZNF594 other 1 1 1 0.826068023117587 -0.229472505993394 7.24408336472514e-11 -10.1220131879389 172.463773488152 -0.0586906628749736 0.953225263224521 -833.834924746246 208.256273813426 -4.00388861990909 7.31796850312358e-05 PCGF5 other 5.35120438152246e-07 0.588071948911011 1 -0.0586906628749736 -4.00388861990909 0.0340330681969253 29.6275547964705 68.7880524740304 0.430707858863367 0.666892672086074 -138.977526814883 53.7343766090192 -2.58638018313877 0.0100206027839452 SLC47A2 other 1 1 1 0.430707858863367 -2.58638018313877 8.27260289451471e-07 4.73188610093013 11.6082032123878 0.407632948386057 0.683742334864755 49.566312093236 14.09457134866 3.51669524862482 0.000482558323203606 PRF1 other 0.00504132420391726 1 1 0.407632948386057 3.51669524862482 0.328256030780983 -9.0509213147407 9.24480309324383 -0.97902802509176 0.328107804735495 -16.2396006632807 11.0269965275846 -1.47271295702837 0.141548305148215 MAB21L1 other 1 1 1 -0.97902802509176 -1.47271295702837 0.0131985537455271 11.6265755531175 10.582163310761 1.0986955324432 0.272511423298966 -23.8957089665062 14.3145551041959 -1.66932948963966 0.0957748746595784 CHRM4 other 1 1 1 1.0986955324432 -1.66932948963966 0.971058298598202 -2.35294419749349 13.3594100730455 -0.176126354728858 0.860276451670604 -3.98188030214364 16.4379556371158 -0.242236953916145 0.808710463022709 SHISA2 other 1 1 1 -0.176126354728858 -0.242236953916145 0.0765731576235926 -3.84165572246124 12.659789299758 -0.303453369680859 0.761688795250401 -23.3401415440872 16.188389469306 -1.44178280293672 0.150079888438398 GPR157 other 1 1 1 -0.303453369680859 -1.44178280293672 2.4935772657492e-05 177.747635533031 42.5919440203785 4.17326890380928 3.62589216182181e-05 117.263904255445 51.1400756914064 2.29299434289164 0.0223235583394311 PIPSL other 0.133082218673035 1 0.307403137479253 4.17326890380928 2.29299434289164 3.12467702362337e-06 -51.1011502749131 70.4435700819608 -0.725419654561192 0.468582012859055 -419.99056794824 100.55454284526 -4.17674384532331 3.57006266382111e-05 WDFY3-AS2 other 0.0182074930166534 0.293673354725925 1 -0.725419654561192 -4.17674384532331 9.00554466789272e-08 -85.2011263073218 115.803280121736 -0.735740181260457 0.462287181780999 -609.232099758647 141.651630749571 -4.30091836242761 2.10389588635435e-05 ZDHHC20 other 0.000582838850906017 0.175044137744682 1 -0.735740181260457 -4.30091836242761 0.0403808471174814 82.9823728801854 36.7817583542981 2.25607411371862 0.0245584454778901 -35.0671248946138 26.8052054914391 -1.30822070757165 0.191484569048124 ZFP3 other 1 1 1 2.25607411371862 -1.30822070757165 0.17140180339576 -20.435559467445 42.9936963902972 -0.475315248122209 0.634800320950331 -102.800319485645 60.2856610476473 -1.70522007553995 0.0888656748576544 ARSJ other 1 1 1 -0.475315248122209 -1.70522007553995 2.11533000659506e-34 64.0170315900284 128.489553058502 0.498227521741638 0.618574909267932 -1203.11119876537 156.050466607552 -7.70975713767682 8.61677131782198e-14 PPA1 essential 1.94441134206218e-30 8.32293941588425e-10 1 0.498227521741638 -7.70975713767682 0.0844409779429302 73.6461201641109 36.5038390217218 2.0174897254036 0.0442566413819173 25.3082390703938 55.7821249892089 0.453698009448184 0.650271937739617 HOXC10 other 1 1 1 2.0174897254036 0.453698009448184 0.000698692886489797 107.6890960681 42.7482929387146 2.51914377545991 0.0121223217043068 -87.8898856206267 73.7695564253752 -1.19141133388182 0.234143278110761 PSMG4 essential 1 1 1 2.51914377545991 -1.19141133388182 0.790283285698128 -12.3826984777943 19.9722709084833 -0.619994518126362 0.535585285794867 -19.4427423829397 42.2514374694401 -0.460167595410272 0.645625328290434 GREM2 other 1 1 1 -0.619994518126362 -0.460167595410272 0.00375958110769823 29.2281420765026 17.0271549583849 1.71656052628507 0.0867665084142483 -37.1731980223783 27.7176071232017 -1.3411402310866 0.180569955813978 CAPS2 other 1 1 1 1.71656052628507 -1.3411402310866 1.04846887420334e-40 6.27958185476974 4.14656599014065 1.51440538259871 0.130647627635244 -37.3478724552302 5.47534579384169 -6.82109840391024 3.02885490227754e-11 ZNF792 other 9.80632938042387e-37 2.87862369912457e-07 1 1.51440538259871 -6.82109840391024 1.86850795356725e-05 50.0409512044517 97.5937560703434 0.512747466839818 0.608387058282858 -417.180023557459 143.59941072931 -2.90516528890122 0.00385693028779009 D2HGDH other 0.100985944761788 1 1 0.512747466839818 -2.90516528890122 0.683492244909129 31.5508940852772 152.290644501801 0.207175524067758 0.835969284398804 -233.977419416902 336.437683186015 -0.695455447205469 0.48713957128201 OXTR other 1 1 1 0.207175524067758 -0.695455447205469 0.000954957779624728 94.9760108277988 27.4173650912333 3.46408236210005 0.000584422006885618 -14.8448015681638 65.4349930628431 -0.226863347473836 0.820635846170701 CMTR2 other 1 1 1 3.46408236210005 -0.226863347473836 0.00124257573250096 39.9211380568153 11.5998458721333 3.44152314581346 0.000633977295775609 81.1915434547205 33.2136437953517 2.44452382144483 0.0148976122132594 FAM83H other 1 1 1 3.44152314581346 2.44452382144483 0.0875995181316518 33.1683828306474 35.0753006805975 0.945633599343456 0.344859257933306 -55.2509841614531 53.5991517340105 -1.03081825689406 0.303197528611172 GPR62 other 1 1 1 0.945633599343456 -1.03081825689406 0.00777486090896793 14.7709435562718 9.78045588888404 1.51025102756812 0.131702086803256 -26.6210283800098 17.9238794065856 -1.48522692973647 0.138204713096838 ST20 other 1 1 1 1.51025102756812 -1.48522692973647 1.49566042619985e-19 290.7700168651 75.9689341930565 3.82748580000055 0.000148351404665013 -632.521781020918 122.762149894368 -5.15241694256071 3.90050020659257e-07 PITPNB other 1.27176006039773e-15 0.00348977753483837 1 3.82748580000055 -5.15241694256071 8.36206473663509e-15 71.2701005025134 28.1210343954267 2.53440536718322 0.0116127279695227 -191.58040201005 42.5184720329451 -4.50581577488499 8.5033968569645e-06 LRRC57 other 6.70303109288669e-11 0.0722703698873413 1 2.53440536718322 -4.50581577488499 0.00639710982280276 89.8547638824178 42.5542991439133 2.1115319883084 0.0352950316891023 -106.110167946354 86.0008502640026 -1.23382696357793 0.217932069504189 MRPL14 essential 1 1 1 2.1115319883084 -1.23382696357793 1.09415859901144e-09 -16.8079416531594 39.0732118116386 -0.430165345356966 0.667287420219168 -223.485529057651 49.0921996715601 -4.55236331948514 6.88634869227303e-06 GPR137C other 7.78056179757037e-06 0.0587612133911658 1 -0.430165345356966 -4.55236331948514 1.8103564983213e-07 0.232469512194741 11.3832496990411 0.0204220691226974 0.983715999944195 -69.4443766937668 16.0032353824952 -4.33939606798054 1.77659540612614e-05 BBS12 other 0.00114993844773369 0.148470078089961 1 0.0204220691226974 -4.33939606798054 3.70219829555018e-18 68.1398792069188 16.8254208443834 4.04981722817737 6.06684590912732e-05 -25.9748332946596 22.4164957065452 -1.15873745989099 0.24719747388686 ZFP82 other 3.10355283115971e-14 1 0.509675724825786 4.04981722817737 -1.15873745989099 0.693512579243087 -82.0653900648304 96.2041427701962 -0.853033847626092 0.394107831871406 -52.350049375294 222.040080613255 -0.235768466804317 0.813722791390454 NQO1 other 1 1 1 -0.853033847626092 -0.235768466804317 0.365299596665167 -104.754013231804 78.6809073423229 -1.33137779888637 0.183757239956402 -170.016152789911 152.448945576894 -1.11523337958514 0.265361939538722 AEN other 1 1 1 -1.33137779888637 -1.11523337958514 1.94534139752262e-43 193.597324129683 30.2831229422609 6.39291147411726 4.18359328161115e-10 -34.24317867342 36.7619506915175 -0.931484266457095 0.352117430449868 FKRP other 1.83270613060606e-39 1 3.95893432238863e-06 6.39291147411726 -0.931484266457095 0.391590347884494 12.0176794656213 8.93406387479335 1.34515262416336 0.179278395851527 1.21991099880151 6.35423873424871 0.191983815815152 0.847844675579091 RPH3AL other 1 1 1 1.34515262416336 0.191983815815152 5.81146849687298e-12 206.709559917881 28.3628966225366 7.28802712462147 1.47839348495287e-12 -22.9385922650373 79.7088829048777 -0.287779622911183 0.773651551150264 SLC26A11 other 4.40218738638128e-08 1 1.42221453252466e-08 7.28802712462147 -0.287779622911183 5.21627515013869e-10 -61.3493334826939 166.459023652752 -0.36855516833184 0.712637386155988 -1497.09320040328 267.550129641984 -5.59556148377345 3.88199900166116e-08 HIGD1A other 3.75832624567493e-06 0.000355397008602079 1 -0.36855516833184 -5.59556148377345 0.0142805545125859 23.3779927188735 13.5226155749518 1.72880701882682 0.0845483043809264 109.230931915682 38.7190779807599 2.82111397306414 0.00500326941202484 MAPK15 other 1 1 1 1.72880701882682 2.82111397306414 4.85750613634196e-10 396.48964281249 68.3195706469468 5.80345630187606 1.26217322186845e-08 -112.68886758638 143.983341359999 -0.782652121571662 0.434262220167163 EHMT1 other 3.50469067737072e-06 1 0.000117230648847142 5.80345630187606 -0.782652121571662 0.00205952662175355 231.707183663549 270.256894708925 0.857359009889851 0.391716441094153 -1259.9256867631 495.929495120604 -2.54053388467387 0.0114133530882987 NPM1 essential 1 1 1 0.857359009889851 -2.54053388467387 4.52439704717994e-25 408.904503417768 66.0537277218143 6.19048337650029 1.38830526008133e-09 -596.526174300811 136.130749216536 -4.38200904449551 1.47564884070283e-05 DHTKD1 other 4.00635358527783e-21 0.123733155292932 1.30681174131456e-05 6.19048337650029 -4.38200904449551 0.317411754024057 -10.0839025439681 13.3595311002919 -0.754809616315636 0.450768875589684 -32.0491045016939 21.2192897446327 -1.51037593092863 0.131668588168738 C4orf50 other 1 1 1 -0.754809616315636 -1.51037593092863 0.0560177230492452 -181.087501699058 421.774826032076 -0.429346396518427 0.667882270537304 -741.983892891123 315.277265003071 -2.35343291525919 0.0190420782914233 POLR2A essential 1 1 1 -0.429346396518427 -2.35343291525919 0.000961789093190105 203.532543062353 55.4121124331109 3.67306955330463 0.000269439697049052 29.6555965168757 103.726418221908 0.285902058754519 0.775088921712297 TMEM132C other 1 1 1 3.67306955330463 0.285902058754519 9.41779196761426e-10 63.6400602687364 22.386222839355 2.84282260233992 0.00468066943067405 -38.5292931440513 28.2855741889963 -1.36215347394433 0.173849540245515 FRAT2 other 6.71111855612192e-06 1 1 2.84282260233992 -1.36215347394433 0.603118389701682 6.64955144760103 8.54415787830672 0.778257090085376 0.436837672613517 -4.24772325676228 6.38676981499632 -0.665081626519325 0.506348322572347 TMEM102 other 1 1 1 0.778257090085376 -0.665081626519325 0.114725344000924 -115.102430475489 173.866823837655 -0.662014914259687 0.508309811359423 -779.970937293428 374.57766766505 -2.0822675899378 0.0378978739197963 TMEM132E other 1 1 1 -0.662014914259687 -2.0822675899378 1.43460364830082e-05 56.8802046485946 28.3603930224609 2.00562117046638 0.0455155040590459 -190.573648761353 60.3292817027803 -3.15889139373875 0.00169412007596328 ZNF322 other 0.07854454974447 1 1 2.00562117046638 -3.15889139373875 0.580857671374224 -3.58044508019882 9.41684469220746 -0.380217068161024 0.703968599388437 15.3658310665042 20.5663491117043 0.747134602405415 0.455383199524268 NME9 other 1 1 1 -0.380217068161024 0.747134602405415 0.0609613133260135 857.24061616348 417.278537335988 2.05436067149852 0.0405349995410969 -405.74798397788 309.873371230783 -1.30939932775215 0.191087137653185 LRRC75A other 1 1 1 2.05436067149852 -1.30939932775215 0.0011173606929088 38.5448969659446 68.0058319849973 0.566788109796936 0.571149142110538 -195.262656652692 91.289387540054 -2.13894146860191 0.0329940530879191 DDX60L other 1 1 1 0.566788109796936 -2.13894146860191 1.0420400544762e-08 253.202400132503 41.4115740114375 6.11429065851424 2.16006512056421e-09 27.3151089897054 109.204367938248 0.250128355718804 0.802606172403313 OGFOD3 other 7.10567113147323e-05 1 2.02959718728213e-05 6.11429065851424 0.250128355718804 0.0789134890434595 75.4111565129767 33.4178515227403 2.25661295016709 0.0245312994103517 62.1758254708477 38.2597073843272 1.62509934658616 0.104870686545193 WASHC1 other 1 1 1 2.25661295016709 1.62509934658616 0.364364872592055 -175.1740456374 231.351884326038 -0.757175789372571 0.449358284151335 -823.650488568016 625.272487280711 -1.31726648033091 0.18844917454159 AATK other 1 1 1 -0.757175789372571 -1.31726648033091 0.247791959713781 -472.186231268899 367.048324118061 -1.28644159431449 0.198968542675785 -913.86479311786 560.436776256458 -1.63062959433567 0.103687331918392 DDN other 1 1 1 -1.28644159431449 -1.63062959433567 0.0180555995258322 87.7778739612194 34.4980208692297 2.54443216594817 0.011287835116189 3.58973090621349 67.4199153820868 0.0532443697959204 0.957561479289834 TMEM45A other 1 1 1 2.54443216594817 0.0532443697959204 3.27704413161717e-05 49.6305618938961 27.4254313614681 1.8096547412423 0.0710346778381573 -46.5483773848007 36.1539869075355 -1.28750329815212 0.198598804967838 ZBTB2 other 0.172634684853592 1 1 1.8096547412423 -1.28750329815212 0.00104820691229206 32.7100873191706 32.2092905250219 1.01554820941367 0.310407790838388 249.561579564706 66.8503208570718 3.73313959252757 0.000214163041590335 RNF135 other 1 1 1 1.01554820941367 3.73313959252757 0.22562949281672 1.68957516992829 31.3694872425344 0.0538604650074537 0.957070892516271 -118.442310123098 70.2569209318629 -1.68584544486325 0.0925377478103473 ACBD4 other 1 1 1 0.0538604650074537 -1.68584544486325 9.35788379375835e-09 176.338284167661 30.7503455636076 5.73451390336095 1.82467102575445e-08 275.010498019153 86.4183840752902 3.1823147465886 0.00156504172666879 SGSH other 6.39798514979258e-05 1 0.000169074017246408 5.73451390336095 3.1823147465886 7.05491005074783e-06 39.82700700654 125.378711683023 0.317653662826182 0.750899388309409 -717.50862546887 195.163423393046 -3.67645029480682 0.000265931995031522 SETD2 other 0.039782637776167 1 1 0.317653662826182 -3.67645029480682 0.104984859289403 -42.6675519013597 54.4707692053752 -0.78331098539268 0.433868820758138 -175.473826731425 85.7271174580195 -2.04688821850746 0.0412666884193948 TMIE other 1 1 1 -0.78331098539268 -2.04688821850746 0.000883096901784229 0.887085174149925 14.4153157307723 0.0615376860776117 0.950959072067847 -34.8809976369056 16.7720807497797 -2.07970603989393 0.0381335523337035 GPR135 other 1 1 1 0.0615376860776117 -2.07970603989393 0.507746233398211 -5.10424869249313 62.7634321507619 -0.0813252003209828 0.935220566174342 -151.137327378512 137.077404925784 -1.10256921963426 0.27082111461779 P2RY13 other 1 1 1 -0.0813252003209828 -1.10256921963426 3.28110453658792e-14 125.642651254334 20.2977632731305 6.18997519892531 1.38737498224607e-09 -208.537061929759 64.5250748037581 -3.23187632969025 0.00132284634117107 ZFP41 other 2.6068375543191e-10 1 1.30607480828645e-05 6.18997519892531 -3.23187632969025 2.76752286725947e-05 3.55666313842756 31.0134418986103 0.114681342046944 0.908750255557893 -95.7544151458402 40.0137190847913 -2.39303962080933 0.0171296523402848 GPR88 other 0.147066165166168 1 1 0.114681342046944 -2.39303962080933 1.74010595988296e-57 319.463814758054 36.9946930926416 8.63539572981606 1.11190205777157e-16 -75.2112507085639 48.6353003242276 -1.54643335616656 0.122725450326281 HKR1 other 1.67955027247903e-53 1 1.0821030826233e-12 8.63539572981606 -1.54643335616656 0.000633794060886131 604.593926868072 684.00770764516 0.883899289599402 0.377236600524947 -4028.28430615487 1358.61823504255 -2.96498619130391 0.00319268136648649 ZBTB20 other 1 1 1 0.883899289599402 -2.96498619130391 0.203236946598122 -31.5449535690839 46.2123912931277 -0.682608120601086 0.495215356059536 -180.494301660257 100.927667778957 -1.78835304166108 0.0744101241402378 C3orf58 other 1 1 1 -0.682608120601086 -1.78835304166108 0.0257675245317279 -9.30514559234162 85.3803319902395 -0.108984649923888 0.913264576221978 -183.669594764291 113.554372557713 -1.6174594656929 0.106499043916031 AMIGO1 other 1 1 1 -0.108984649923888 -1.6174594656929 0.658938113481771 9.40649452816361 14.3004160961114 0.657777680379624 0.511027328789231 3.99915562392952 18.3686638369288 0.217716196421948 0.827751863711224 GPR3 other 1 1 1 0.657777680379624 0.217716196421948 0.00363474711109244 8.45670715947278 2.54135065031752 3.32764278649079 0.000950777728000224 1.2702172624025 7.32353173616338 0.173443265921851 0.862384258152092 ODF3L2 other 1 1 1 3.32764278649079 0.173443265921851 0.0530211906458841 50.0125629958288 28.0940482863963 1.78018356364988 0.0757422396443534 -50.2450748715973 60.7355357704213 -0.827276391559669 0.408532962578975 SIAH2 other 1 1 1 1.78018356364988 -0.827276391559669 0.0819448232190961 57.2602371432516 143.926790443361 0.397842798876177 0.690940784877722 -534.989501880995 294.064414455553 -1.81929358188921 0.0695523847636099 COPG1 essential 1 1 1 0.397842798876177 -1.81929358188921 0.000329651478282623 1899.49054401338 472.518361759059 4.01992958949169 6.85370576569102e-05 2402.18402947641 1502.18913740724 1.59912222080273 0.110514513592985 ADGRB1 other 1 1 0.574546154337878 4.01992958949169 1.59912222080273 3.98821289503187e-08 5.7442251886245 1.78772577016054 3.21314671662905 0.0014098308298055 -5.23551529723904 2.9405047111847 -1.78048185990823 0.0756901960182763 LINC00471 other 0.000262982758298401 1 1 3.21314671662905 -1.78048185990823 0.00175850747691589 2.02711436163273 1.49181656098449 1.35882280345177 0.17490526846776 -6.12700699697393 3.07403991541927 -1.99314490558209 0.0468683499776644 CELF2-AS1 other 1 1 1 1.35882280345177 -1.99314490558209 0.040268433058136 64.0825438514196 72.1761865881197 0.88786269932925 0.37510190168559 -291.869618234689 157.632487254583 -1.85158290221804 0.0647585667489596 SLC9A9 other 1 1 1 0.88786269932925 -1.85158290221804 2.2247358315764e-63 159.631641160617 31.439503704491 5.07742242565409 5.66918653988185e-07 -249.595038710005 40.3713859860673 -6.18247386394273 1.44678505882297e-09 LSM10 essential 2.160663439627e-59 1.35202063747007e-05 0.00511644085224337 5.07742242565409 -6.18247386394273 0.275369800730433 -0.188926323818485 15.7415468842005 -0.0120017635629004 0.990429685133993 -34.1458873908488 25.535633451431 -1.33718583703022 0.181857591888294 RELL1 other 1 1 1 -0.0120017635629004 -1.33718583703022 0.000648119699581098 151.484143306665 117.294418659688 1.29148637281859 0.19721775201383 -353.587551158918 178.880732821323 -1.97666649494389 0.0487076027671643 RFX7 other 1 1 1 1.29148637281859 -1.97666649494389 1.15097028782786e-07 58.2249798813536 24.7045115570566 2.3568561453595 0.0188758152625539 -100.891684055349 32.7836655517793 -3.07749857611249 0.00222032000589263 SLC35C1 other 0.00073777195449766 1 1 2.3568561453595 -3.07749857611249 0.673863993387828 0.651617091595946 8.71945636663832 0.0747313896872184 0.940462550659685 13.8048613921491 16.8823298625799 0.817710677644551 0.413967005226047 TIGIT other 1 1 1 0.0747313896872184 0.817710677644551 3.48427194975507e-09 -20.7796840888683 88.278439133323 -0.2353879870654 0.814018127965384 -737.587363554644 140.584078879657 -5.24659242662914 2.4230664373778e-07 RNF41 other 2.42470484983455e-05 0.00217760980727143 1 -0.2353879870654 -5.24659242662914 2.83682654315413e-06 -18.0768315889634 20.8878869024581 -0.865421747703746 0.387281106501446 79.3634633682206 15.6137243093774 5.08292972231846 5.51610294603157e-07 SLC2A4 other 0.0165925984509085 0.00490436712931667 1 -0.865421747703746 5.08292972231846 0.052690228283591 -0.259656336368987 3.32033048054318 -0.0782019554651407 0.937703118913878 6.04206877803451 2.48195162015757 2.43440231830584 0.0153149394812745 CLDN7 other 1 1 1 -0.0782019554651407 2.43440231830584 1.6078644974284e-34 -22.0579758097136 22.837852831721 -0.965851561101045 0.33465265732219 -203.097105804934 28.5086714979725 -7.12404665434437 4.34888065391948e-12 ZNF329 other 1.47859219183516e-30 4.16274856193173e-08 1 -0.965851561101045 -7.12404665434437 2.69178286776922e-27 56.8658891523973 73.448250218791 0.774230686000042 0.439212093753855 -647.798358806779 94.5893739644833 -6.84853204599933 2.53479338494044e-11 ADO other 2.41183744952122e-23 2.41160242643233e-07 1 0.774230686000042 -6.84853204599933 6.91923657438357e-14 94.1657269426551 50.6882696033224 1.85774199197526 0.0638765186966794 -395.696975646448 77.3946331964913 -5.11271853491241 4.75493558675667e-07 PRKAG1 other 5.45996958084608e-10 0.00424092704982828 1 1.85774199197526 -5.11271853491241 0.108835797057092 61.7496064847041 39.304750295973 1.57104690959023 0.116893829940627 -69.3812940139267 90.7142126897396 -0.764833778045612 0.444782408600768 GINS3 essential 1 1 1 1.57104690959023 -0.764833778045612 0.000768124386376996 15.7808243410577 38.5971319077469 0.408860025630305 0.682843137391503 -184.305482882868 62.8373856262812 -2.93305459872258 0.0035333800185728 CCDC149 other 1 1 1 0.408860025630305 -2.93305459872258 6.40770913802372e-10 113.588241168393 41.296303119621 2.7505668204577 0.00619573734106871 -301.06785669704 80.0140476191942 -3.7626874986989 0.000190965051609971 MRPS11 essential 4.59753130653202e-06 1 1 2.7505668204577 -3.7626874986989 4.50396424191838e-05 150.091654975139 33.6422557477031 4.46140282924953 1.03703318318441e-05 171.066827621424 43.4248260458541 3.93937853523668 9.50725076653716e-05 RTKN2 other 0.233080149519276 0.758203248631338 0.0900041099685746 4.46140282924953 3.93937853523668 9.20604806188466e-16 -160.861253717452 210.747473442902 -0.763289120811378 0.445702847117813 -1249.71157864028 244.692557523288 -5.10727253533792 4.89037491376817e-07 CHST15 other 7.49188191276174e-12 0.0043602582731157 1 -0.763289120811378 -5.10727253533792 0.0263294864179842 -171.373612357225 110.539214355913 -1.55034223244466 0.12178327257085 -482.654096977658 178.249255572709 -2.70774817783617 0.00703986251594063 MGAT4C other 1 1 1 -1.55034223244466 -2.70774817783617 2.45297571390033e-05 437.503229579361 233.159930944561 1.87640829968931 0.0612639213185894 -1165.18519240495 443.745694829338 -2.62579492259204 0.00894738282632982 IDH2 other 0.131062492393694 1 1 1.87640829968931 -2.62579492259204 8.802505214061e-09 384.080866807612 89.0688682201599 4.31217859261715 1.99895120204976e-05 -330.81531259438 173.472725800012 -1.90701628206247 0.0571724188185758 WRB essential 6.02971607163179e-05 1 0.171470034111828 4.31217859261715 -1.90701628206247 2.26021617189821e-10 819.261092844842 122.136291201094 6.70776134421792 6.16551981077672e-11 -27.0102160638788 485.844566814263 -0.0555943565263841 0.955690485358569 TNRC18 other 1.64430726505595e-06 1 5.87697348363237e-07 6.70776134421792 -0.0555943565263841 0.400539149811325 -6.35832314498543 5.73223256491719 -1.10922281553964 0.267946917482173 -8.89210224479754 6.57181761660441 -1.35306588885405 0.176737352353245 TMEM30B other 1 1 1 -1.10922281553964 -1.35306588885405 2.71637137655339e-08 274.557196952124 60.4533396804373 4.54163820234683 7.22950850751192e-06 -43.9124315735759 96.8887717008497 -0.453225185980873 0.650611553399223 NOP10 essential 0.000181181970816111 1 0.0631569863216241 4.54163820234683 -0.453225185980873 0.00207679228282839 37.8522244391313 208.727834908095 0.181347276733828 0.856179272651079 -1135.76675754299 383.037603360202 -2.96515733071496 0.00319132647276658 KCNIP1 other 1 1 1 0.181347276733828 -2.96515733071496 6.13294408433172e-12 620.568187666184 105.980541499048 5.85549176186985 9.35595210916424e-09 -589.00190254894 252.938988621612 -2.32863231468861 0.0203338231453351 IST1 other 4.64325196624754e-08 1 8.71319819926466e-05 5.85549176186985 -2.32863231468861 0.0001783476840437 151.211194483344 41.5168143836584 3.64216755857026 0.00030277909332604 -52.5275489444892 90.5357027562611 -0.580186018833952 0.562088208256326 ERCC6L2 other 0.855177144989543 1 1 3.64216755857026 -0.580186018833952 0.000848804844454866 248.210353019633 66.1023592482472 3.75493939766174 0.000197233006134134 141.311226190974 139.310573327893 1.01436109848153 0.310980889400445 MRPL41 essential 1 1 1 3.75493939766174 1.01436109848153 0.315163013202633 0.196911196911062 56.1923986623215 0.00350423191745855 0.997205628605622 -89.9562419562419 79.8654612648521 -1.12634724111749 0.260635302874017 UNC5C other 1 1 1 0.00350423191745855 -1.12634724111749 0.0946657863340195 392.505140738245 955.185933596121 0.410920143328039 0.681332054004386 -3047.03440268181 1877.79032602835 -1.6226701993542 0.105379429506205 RGMA other 1 1 1 0.410920143328039 -1.6226701993542 2.12662413446897e-36 236.950041220118 77.0990016765478 3.07332178196276 0.00224908560561345 -530.530090684254 93.4668180809088 -5.67613300182108 2.51033806550956e-08 MRPS16 essential 1.96755264921069e-32 0.000230474137794433 1 3.07332178196276 -5.67613300182108 4.64829985796487e-05 -0.980555512045311 8.50971632517808 -0.115227755494516 0.908317526242712 -24.0074324112651 9.70371915564104 -2.47404443865309 0.0137381583602865 RAD51B other 0.240084687663885 1 1 -0.115227755494516 -2.47404443865309 1.44886020933682e-05 815.009779342816 170.450878367937 4.78149357249734 2.38532348848323e-06 692.845846171499 347.875461778135 1.99164908795257 0.047034412874026 ARL6IP4 other 0.0792816306549108 1 0.0211625899898232 4.78149357249734 1.99164908795257 3.43274353853383e-05 465.657677026427 257.721497461665 1.80682512562108 0.0714835925195645 -1143.67661473719 448.129883467238 -2.55210968277414 0.0110496717482598 SHMT2 other 0.180425000385338 1 1 1.80682512562108 -2.55210968277414 2.56082903057397e-13 202.968753784668 43.4607319769014 4.67016418160059 4.00887983772694e-06 -1.75778621973169 50.1322236421003 -0.0350630012400951 0.972045477388994 MOB2 other 1.99975138997521e-09 1 0.0353422846494007 4.67016418160059 -0.0350630012400951 3.65530989994875e-09 2.58852606596285 48.694337377534 0.0531586670107788 0.957629724330545 -218.362582862755 57.6429857724355 -3.78819001022627 0.000172953033341045 HHIPL1 other 2.54190250442436e-05 1 1 0.0531586670107788 -3.78819001022627 0.840788555336633 24.7908001449867 45.5152041530629 0.544670744782728 0.586257185549771 -8.28537447329076 34.0226779687956 -0.243525053521355 0.807712694470211 CYB5D1 other 1 1 1 0.544670744782728 -0.243525053521355 0.0270610774077336 85.3796687808316 48.337675761253 1.76631721397889 0.078039156967347 247.865549179502 94.1436501967788 2.63284404908259 0.00876668719190513 BACE2 other 1 1 1 1.76631721397889 2.63284404908259 0.00646089840021216 82.4840715148406 63.0400264597248 1.30843967154008 0.1914135418288 -264.407379175162 128.655804256841 -2.05515313282963 0.0404594183314767 UBE2E2 other 1 1 1 1.30843967154008 -2.05515313282963 0.0377554744181009 300.211445748595 563.240671225991 0.533007400007412 0.594299402062645 -1888.93182353728 1039.62155324578 -1.8169417685117 0.0699108694636993 SYNM other 1 1 1 0.533007400007412 -1.8169417685117 0.608339589337977 -4.91818891849674 9.74378044870032 -0.504751615083112 0.613988314114405 -12.004323256455 12.2170802420381 -0.982585283769277 0.326356512868828 KCNA4 other 1 1 1 -0.504751615083112 -0.982585283769277 0.553277844746016 -1.52086778226147 23.5873888643058 -0.0644780052175663 0.948619103814024 -36.7196276208754 40.034917111485 -0.917190049841304 0.359548956660344 GABRG3 other 1 1 1 -0.0644780052175663 -0.917190049841304 5.69852345151273e-07 2.30451675570665 2.91376903004245 0.790905775971224 0.429427998998595 -14.8337172109634 4.25925402378474 -3.48270310437654 0.000546387204853368 PRR34 other 0.00351712867427365 1 1 0.790905775971224 -3.48270310437654 9.69224634917798e-10 523.302266802883 255.397626056251 2.04897075545889 0.0410616505340738 -625.682641993408 296.485804157305 -2.11032917333689 0.0353977143303672 B4GALNT4 other 6.90378707451947e-06 1 1 2.04897075545889 -2.11032917333689 3.12924257809974e-22 933.991510232444 101.929072713588 9.16315125182081 2.0829401869798e-18 -396.435208080004 275.717695890341 -1.43783012113113 0.151209592615855 C8orf33 other 2.72807367958735e-18 1 2.0319081523988e-14 9.16315125182081 -1.43783012113113 4.34691957736006e-19 50.7227064335743 26.7469742816276 1.89639044399933 0.0585676967378267 -90.6006347926839 33.4500937715374 -2.70853156381211 0.00702354301352597 SPACA6 other 3.68357964985491e-15 1 1 1.89639044399933 -2.70853156381211 4.51894588221616e-64 30.4873238071504 6.50951253662756 4.68350335537493 3.7730349429998e-06 -40.3176455927556 8.12696753049758 -4.96097042857105 1.00717171841253e-06 ZSCAN22 other 4.39105971374944e-60 0.00887620435436967 0.0332857142671442 4.68350335537493 -4.96097042857105 9.20416479251361e-33 45.333720258445 9.64737364200416 4.69907375216238 3.50478866267467e-06 -18.1602417663573 11.7716636245806 -1.54270818004318 0.123623746515377 KCNJ14 other 8.42181078514995e-29 1 0.0309577982574053 4.69907375216238 -1.54270818004318 4.40235072228087e-08 116.536503580992 22.0827031486053 5.27727528630716 2.07533437728279e-07 -38.80062149004 61.2658676485475 -0.633315465515323 0.526861238734702 FBXL6 other 0.000289718701033304 1 0.00188917688364052 5.27727528630716 -0.633315465515323 0.0710388264973527 0.774207703896212 3.3875711203582 0.22854360141503 0.819330327238695 -5.69058815805842 2.46873841982748 -2.30505918016866 0.0216299438712159 GLTPD2 other 1 1 1 0.22854360141503 -2.30505918016866 4.57949307919317e-06 66.9708993668642 22.1465071653784 3.02399375516694 0.00264158282622389 -85.211451492392 42.1525769602147 -2.02150040726616 0.043837027440907 YBEY other 0.0263595621638359 1 1 3.02399375516694 -2.02150040726616 0.582873834482963 -3.97820163487744 31.5207416832079 -0.126209011033416 0.899624925093971 -51.1946599220372 54.8059318773871 -0.934108009267517 0.350767591403063 NXPH4 other 1 1 1 -0.126209011033416 -0.934108009267517 3.60197653468988e-10 2.56689839454347 66.4964372476838 0.0386020439709028 0.969225422647304 -417.890504631923 88.1510399940299 -4.74061910852356 2.89363942153027e-06 TRAPPC6B other 2.60603002284813e-06 0.0250791728664029 1 0.0386020439709028 -4.74061910852356 1.99730118754033e-06 9.52835637409563 13.715409429994 0.694719061995934 0.487600571133967 -81.6697207274077 21.9817330203908 -3.71534494808252 0.000229247497600392 PGBD4 other 0.0118300149338014 1 1 0.694719061995934 -3.71534494808252 1.72819895891439e-20 716.660390063909 71.2475695882819 10.0587345534068 1.52247086369433e-21 345.856843891831 187.887454001315 1.84076603587065 0.0663351607587713 NPLOC4 essential 1.48262188685265e-16 1 1.49065122264312e-17 10.0587345534068 1.84076603587065 6.30915100002077e-20 242.586855649696 43.7336513834542 5.54691520089891 5.04453348204645e-08 -6.36016470029303 60.2977053272625 -0.105479382105398 0.916043827693628 CAPN12 other 5.38233671811772e-16 1 0.000463945744343812 5.54691520089891 -0.105479382105398 0.000117122677151154 30.8024848903784 56.9485291501772 0.540882887583454 0.588863267466065 -407.863118342459 114.18838827986 -3.57184407702509 0.00039377992354333 CEP97 other 0.575892203552224 1 1 0.540882887583454 -3.57184407702509 0.087550169334886 8.74282981196556 30.6161372605467 0.285562797735166 0.775348302807916 -102.477000339252 59.3232676474908 -1.72743350801558 0.0847963858064074 FES other 1 1 1 0.285562797735166 -1.72743350801558 2.08433711526644e-20 240.643312048183 68.2649147927726 3.52513897920606 0.000468058922995043 -225.607817864341 81.1341351558433 -2.78067693001215 0.00565954153425355 GLRX5 essential 1.78669377520639e-16 1 1 3.52513897920606 -2.78067693001215 0.209384209497375 -119.138818982562 123.302552865298 -0.966231567911778 0.334463955594563 -344.349698903467 194.724795129877 -1.76839163535283 0.0776946659110394 LIMK2 other 1 1 1 -0.966231567911778 -1.76839163535283 0.00446876612662472 133.950742278597 40.9235089150668 3.27319787158526 0.00114761505222344 97.1394507826935 63.8070614735645 1.52239342385229 0.128632144147893 MFSD5 other 1 1 1 3.27319787158526 1.52239342385229 1.45136784755875e-20 93.6448623510649 15.962187987452 5.86666830541527 8.77695141420958e-09 -32.0014460775992 21.0843346179147 -1.51778306773829 0.129790516629528 RWDD4 other 1.24657984426821e-16 1 8.1792410229019e-05 5.86666830541527 -1.51778306773829 4.47181968895543e-14 5.05433776070087 6.36726526528987 0.793800407257065 0.427741469230405 37.2234599809268 4.64023095934057 8.02189811392852 9.61546898847743e-15 SPNS3 other 3.54257555759049e-10 9.32412027812657e-11 1 0.793800407257065 8.02189811392852 0.0740487009637748 89.7780218509726 298.881471635164 0.300380018071385 0.764029821191779 -1180.40369385515 615.807810904864 -1.91683780710847 0.0559088734531742 SATB1 other 1 1 1 0.300380018071385 -1.91683780710847 0.812883463457362 -46.6460859741135 82.6222560287605 -0.564570470671682 0.572654960756929 42.8746601028392 196.618560234009 0.218060085740692 0.82748385138225 NXPH3 other 1 1 1 -0.564570470671682 0.218060085740692 0.866045928684694 -416.783058165371 840.183870297814 -0.496061722796031 0.620099691609463 -56.9967075400979 1578.62426307543 -0.0361053031258107 0.971214842642175 CSF1R other 1 1 1 -0.496061722796031 -0.0361053031258107 0.00614274662271402 -166.949093784209 211.444261203143 -0.789565499835507 0.430211720803244 -916.601259839782 326.137637717037 -2.81047371979508 0.00517018849206638 C2orf82 other 1 1 1 -0.789565499835507 -2.81047371979508 2.04244193732695e-05 -62.7369216982194 155.036273436088 -0.404659634211874 0.685925257486114 -998.639688585195 249.190306099393 -4.00753827152038 7.20978754491082e-05 TRAK1 other 0.109985498325056 0.579883212237177 1 -0.404659634211874 -4.00753827152038 1.44828404618707e-07 19.1105331273954 3.49161717002817 5.47326129893019 7.46830430581028e-08 -4.81811036039986 9.2077675661763 -0.523265854157597 0.601055090296957 TSPAN10 other 0.000924584535085825 1 0.000684992870928919 5.47326129893019 -0.523265854157597 5.21293027378849e-05 122.744349906937 127.90312275865 0.959666560593306 0.337757378590746 -667.706579996926 220.45349790013 -3.02878650761718 0.00260191585257033 NDN other 0.267423323045349 1 1 0.959666560593306 -3.02878650761718 0.000918304224268656 1384.23456097716 862.829523324805 1.60429670468761 0.109371093836897 -4116.58602854111 1705.01794564528 -2.41439454584928 0.0161713222166194 TTC3 other 1 1 1 1.60429670468761 -2.41439454584928 6.41285774874797e-06 -56.6699483320901 94.5278724924649 -0.599505170674474 0.54914818080107 -962.752910136925 199.835563986024 -4.81772558864577 2.00883774715293e-06 IGIP other 0.0363416648621547 0.0175351446948979 1 -0.599505170674474 -4.81772558864577 0.807166796997257 -172.931493897196 359.084321269369 -0.481590210583075 0.630337604083892 -364.251962638241 564.028343563125 -0.645804358584462 0.518744249942321 ANXA2 other 1 1 1 -0.481590210583075 -0.645804358584462 0.0749441596489968 -90.1598077338511 117.277102309107 -0.768775881725125 0.442440693333862 -237.819723482395 133.592319931785 -1.78019008580606 0.075737991023343 RGS6 other 1 1 1 -0.768775881725125 -1.78019008580606 0.132708617880224 24.6381849095345 18.7278033437108 1.31559395714226 0.188998573827393 73.9038560246372 42.2907046702042 1.74752008983917 0.0812479421147503 HOXB4 other 1 1 1 1.31559395714226 1.74752008983917 9.65648928504612e-34 37.762630140994 27.7035390395294 1.36309769257681 0.173552024090752 -213.56726149742 35.5696581428096 -6.00419775303891 4.04029226303597e-09 PAQR7 other 8.86079456795832e-30 3.75262345390781e-05 1 1.36309769257681 -6.00419775303891 0.12568720640721 -17.0518016694094 21.646987929298 -0.787721678651225 0.431286567702128 -92.0773042558197 45.103375089599 -2.04147259651646 0.0418039657267915 PAPPA other 1 1 1 -0.787721678651225 -2.04147259651646 6.82438823184585e-10 216.415735901537 400.097927414984 0.540906915713835 0.588846718983128 -4065.27085265108 761.459021201867 -5.33879137216677 1.50548583622702e-07 NGRN other 4.89240392341029e-06 0.00135960425869663 1 0.540906915713835 -5.33879137216677 1.21144379734085e-32 -15.3514779930824 136.261918736647 -0.112661542824391 0.91035062474837 -1268.15108682082 164.040073302149 -7.73073957657273 7.42470075908223e-14 GRID1 other 1.10774420828847e-28 7.17374587342525e-10 1 -0.112661542824391 -7.73073957657273 5.09702830845246e-09 3171.02179685275 617.525547417407 5.13504552178365 4.2598479033692e-07 -659.455333703374 1210.70929981074 -0.544685114590645 0.586248580321266 RPS17 essential 3.52663388661826e-05 1 0.00385303242859744 5.13504552178365 -0.544685114590645 1.79625010670888e-05 337.752025363105 103.780599444861 3.25448134978785 0.00122424790148048 -146.369531519612 163.345602654605 -0.896072677445201 0.370707278828934 TMEM198B other 0.097320830781487 1 1 3.25448134978785 -0.896072677445201 3.97944004890744e-06 908.330683211853 344.297121305015 2.63821747846436 0.00863183532775687 -283.335557659857 399.772203746694 -0.708742516374114 0.478862179649565 CRIP2 other 0.0230131018028317 1 1 2.63821747846436 -0.708742516374114 3.35814542090266e-05 51.5106811294691 13.8813528124349 3.71078250264814 0.000233226430579558 -39.126781526732 32.0377557920157 -1.22127098354633 0.222640392914198 DDX28 other 0.176772774956316 1 1 3.71078250264814 -1.22127098354633 0.0901865413619076 -65.9105825414627 73.7068475084847 -0.89422604234804 0.371698879447202 216.796461933866 161.961861156209 1.33856489661334 0.181416372899459 PLCXD3 other 1 1 1 -0.89422604234804 1.33856489661334 2.31539249211309e-08 152.691120553812 54.650746623208 2.79394390723603 0.00543592888710825 -180.917043634145 81.0491198187622 -2.23219010938925 0.0261084761097382 RRP7BP other 0.000155108143046656 1 1 2.79394390723603 -2.23219010938925 0.00829961432786362 7.12549065000759 9.65902665795626 0.737702762642055 0.461090117335671 20.9308537655661 7.03914674007288 2.97349302954712 0.00310684968134302 VMO1 other 1 1 1 0.737702762642055 2.97349302954712 0.00011503358162694 70.9066041846945 22.4879189623752 3.15309763892911 0.00172655022413158 -3.21071183748679 33.0207312702368 -0.0972332142256572 0.922585668219066 ALG12 other 0.566195288767797 1 1 3.15309763892911 -0.0972332142256572 0.0244100215817189 0.151151523922611 7.66198181073117 0.0197274709933287 0.984269800886933 -14.267522595425 9.84692555998278 -1.44893170040882 0.148075472800395 LCK og 1 1 1 0.0197274709933287 -1.44893170040882 0.194910469127896 206.47629777765 121.793986839874 1.69529139438641 0.0907308524734398 -11.70812325719 220.179365796368 -0.0531753882333291 0.957616409213537 GALNT9 other 1 1 1 1.69529139438641 -0.0531753882333291 0.622981669344644 192.199437432717 297.828850383942 0.645335188934671 0.519049440168711 543.717304152888 571.886218402242 0.95074384843885 0.342261145373749 COL18A1 other 1 1 1 0.645335188934671 0.95074384843885 0.227253365799136 4.75461913846355 2.76703634299547 1.71830744128081 0.0864472366085878 4.75683604386032 6.43287891064926 0.739456798415037 0.460025777821758 ADGRG3 other 1 1 1 1.71830744128081 0.739456798415037 1.40798529386814e-06 1905.19869139212 498.391309717046 3.82269645205846 0.000151494707637924 -1078.29939063152 927.2937031822 -1.16284558703581 0.245537083698195 RPL35A other 0.00842819996909468 1 1 3.82269645205846 -1.16284558703581 0.258830944877821 -84.4045537088936 61.400822600793 -1.37464858178958 0.169948115730149 -162.832695116657 128.662018184764 -1.26558480438899 0.206339204935281 RGS7 other 1 1 1 -1.37464858178958 -1.26558480438899 5.96446670551124e-05 -422.815171396889 299.667479890238 -1.41094779971373 0.158969868445111 -2094.05654889134 492.98469480319 -4.24771107696828 2.63954800864297e-05 SLC25A18 other 0.304008867979908 0.218818529916503 1 -1.41094779971373 -4.24771107696828 4.62268071447618e-08 34.3168681687086 49.8030732527635 0.689051215665781 0.491161801128362 -334.457634018368 77.4511306389723 -4.31830537861863 1.95305583771489e-05 ZNF721 other 0.000303895030169664 0.162767673515159 1 0.689051215665781 -4.31830537861863 2.11862904935635e-08 16.4615369500712 27.0432195654036 0.608712173129357 0.543031514348463 -286.285107971626 55.2520185362269 -5.18144161165656 3.36973457730226e-07 CEP63 other 0.000142329499535759 0.00301827126088963 1 0.608712173129357 -5.18144161165656 6.15597738460659e-08 650.240903701986 218.082453521915 2.98162870602813 0.00302746356214878 -850.163157279532 352.410773337344 -2.41242102001722 0.0162579449964055 EWSR1 essential 0.000401308165702504 1 1 2.98162870602813 -2.41242102001722 2.93135610798218e-06 188.41514652262 46.7573512598807 4.0296368687652 6.59379374869254e-05 -114.218276839973 97.1972554308221 -1.17511833367831 0.240590192430832 HMGN4 other 0.0171308450950479 1 0.553021481702844 4.0296368687652 -1.17511833367831 0.0319015854233002 -85.8204824738086 80.4426490135521 -1.06685301299999 0.286627244083662 -233.402514773029 98.5764920195375 -2.36772997284961 0.0183321499445621 SPATA13 other 1 1 1 -1.06685301299999 -2.36772997284961 0.00131269449058913 201.625449029771 57.0387363433933 3.53488632384691 0.000451388470237933 210.067131224746 127.74725829428 1.64439639667908 0.100811843925443 GJC1 other 1 1 1 3.53488632384691 1.64439639667908 0.24036727753256 62.8461284708045 41.6695467576915 1.50820283302468 0.132226871417016 23.4772037524585 57.6851033717762 0.406989021084866 0.684215775453681 SOX1 other 1 1 1 1.50820283302468 0.406989021084866 5.45693665058721e-08 88.8440143963525 26.6717043163237 3.3310212704322 0.00093890234680868 -129.981241402703 49.5700469982736 -2.62217305154521 0.00904292348737067 CNOT10 other 0.000356829087581897 1 1 3.3310212704322 -2.62217305154521 8.38341503669102e-21 666.898565449136 199.674602907487 3.33992683965983 0.000909869427003093 -815.094235492546 231.847294377624 -3.51565127244898 0.000484514865686385 MTA1 other 7.22147371260564e-17 1 1 3.33992683965983 -3.51565127244898 0.636216226578543 10.8168788817941 33.7837980175768 0.320179480003001 0.74898495988852 -28.7444270191558 54.3008083374146 -0.529355416599758 0.596827102249432 ZNF662 other 1 1 1 0.320179480003001 -0.529355416599758 3.13108111510521e-26 47.2405401239442 16.367138557346 2.8863041611352 0.00409293665929608 -105.914128948367 24.4531561876713 -4.33130709735403 1.8439226558933e-05 ZNF320 other 2.78885394922421e-22 0.15398598099365 1 2.8863041611352 -4.33130709735403 1.90654275116068e-08 425.087705552064 77.9234774781245 5.4551942406754 8.21504206709321e-08 -320.508262135366 205.492536445785 -1.55970755765101 0.11955453806878 PYCR1 other 0.000128405654290672 1 0.000753155056711105 5.4551942406754 -1.55970755765101 0.0199017545068836 197.128154592001 70.2149407735793 2.80749584661298 0.00521580507700281 2.59446785374487 52.4857652072463 0.049431838204136 0.96059768887141 NAA38 other 1 1 1 2.80749584661298 0.049431838204136 0.167653425324731 -50.6341927770799 59.2813903181929 -0.854133017213343 0.393498192205816 75.1302451176871 43.2021175820618 1.73904079990936 0.0827301715511493 SPNS2 other 1 1 1 -0.854133017213343 1.73904079990936 8.20484872190404e-13 491.413319732488 153.258870376194 3.20642660699671 0.0014423938230558 -288.243698632652 177.875233767984 -1.62048247261128 0.105848352992586 AP2A2 other 6.33004078894896e-09 1 1 3.20642660699671 -1.62048247261128 2.31965536326319e-12 34.5936598152514 12.3335243947083 2.80484788517495 0.00525963095763695 -48.2849806555681 16.3486613300293 -2.95345164236034 0.0033127743657161 SLC25A21 other 1.77268062860573e-08 1 1 2.80484788517495 -2.95345164236034 0.0871731024761614 73.3586445853879 77.354393258523 0.948344903181115 0.343476832628549 333.295798516727 150.657325273218 2.21227741772458 0.0274627328277289 PCP4 other 1 1 1 0.948344903181115 2.21227741772458 3.15602318814106e-08 107.681258844902 17.96529194315 5.99384965107455 4.29909185133456e-09 63.5959636265402 47.6124623061197 1.33569995220277 0.182344182726634 SLC25A10 other 0.000209623060156329 1 4.02480979121941e-05 5.99384965107455 1.33569995220277 0.000164762848157618 81.3785501758134 142.967116602331 0.569211662862104 0.56950494916282 -904.958595772639 289.682178619068 -3.12397055313043 0.00190302463036974 CAMK1D other 0.794815979512347 1 1 0.569211662862104 -3.12397055313043 4.39137862456319e-07 106.63384722933 31.6978737541887 3.36406940276992 0.00083556936940663 -120.436523649621 61.6276694799508 -1.95426055643402 0.0513063382296671 LYSMD4 other 0.00272660698799128 1 1 3.36406940276992 -1.95426055643402 0.100463909672005 -4.57721082571979 3.52132475376667 -1.2998547835793 0.194335959571283 -11.4175683995371 5.31854333777317 -2.14674727165381 0.0323631645787854 WBP2NL other 1 1 1 -1.2998547835793 -2.14674727165381 5.08194533023134e-05 35.9993540051679 8.39313525289695 4.28914260529073 2.20859025153674e-05 13.7382798080472 16.3466773455493 0.840432555046894 0.40112444187589 IGSF5 other 0.261059531613984 1 0.189165755044122 4.28914260529073 0.840432555046894 0.661270211905924 -7.9164981803476 11.0729424854145 -0.714940783877039 0.475027393489993 2.96492519207454 20.7519873761927 0.142874276970503 0.886455326237884 NKX2-5 other 1 1 1 -0.714940783877039 0.142874276970503 0.468306569788399 44.1002543951439 36.4647332293417 1.20939468054734 0.227163630332397 -6.53741511211497 102.47765557294 -0.063793566271253 0.949163704234381 AFMID other 1 1 1 1.20939468054734 -0.063793566271253 0.707151634145379 -6.36424237371795 124.81040472628 -0.0509912806362201 0.959356368752438 107.469968262287 176.429143052143 0.609139546920116 0.542756654002901 GAS6 other 1 1 1 -0.0509912806362201 0.609139546920116 0.223963469411544 -82.1415172831161 97.7976162786968 -0.839913286322183 0.401416277500456 -220.794417971415 132.839262149307 -1.66211716625804 0.0972063782451719 FREM3 other 1 1 1 -0.839913286322183 -1.66211716625804 0.180465819523331 -48.7584635949481 59.6556969521411 -0.81733122042082 0.414183529318341 -116.766265651854 70.6187346589404 -1.65347433957557 0.0989508597393691 BEGAIN other 1 1 1 -0.81733122042082 -1.65347433957557 8.10279545057371e-07 324.66843286173 65.8467753805273 4.93066563982029 1.16792898607231e-06 154.34378948044 86.5254709272293 1.78379600626789 0.0751538177613053 GPC6 other 0.00494027438621479 1 0.0104471247804169 4.93066563982029 1.78379600626789 0.0718182228393856 -111.967375110218 104.313719650333 -1.07337151321553 0.283695455967181 -451.004530390097 195.995394143063 -2.30109759651237 0.0218548911357417 ARHGEF37 other 1 1 1 -1.07337151321553 -2.30109759651237 4.79156798334138e-07 6.78151375792143 26.15454503219 0.259286244496894 0.795536769191217 -90.2758055153236 33.4485231918811 -2.69894742429872 0.00722618563860894 FAM43B other 0.00296645973848665 1 1 0.259286244496894 -2.69894742429872 0.274515232039112 -1.78233138824791 10.3527305071658 -0.172160512341574 0.863391040096342 -39.4071651513092 25.0777121445375 -1.5714019255099 0.11681304068995 PTGDR2 other 1 1 1 -0.172160512341574 -1.5714019255099 2.22347791152271e-11 40.5510879745598 12.7645960563472 3.17684067678709 0.00159419636975798 -35.3986214874671 17.505635326392 -2.02212720803677 0.0437705801802264 CEP57L1 other 1.66271678223668e-07 1 1 3.17684067678709 -2.02212720803677 0.715437111982773 4.49912022738754 6.97496739714921 0.6450381731141 0.51925048918165 -1.07083707595567 8.18304446044764 -0.130860473889824 0.895947602229822 ANKRD20A2 other 1 1 1 0.6450381731141 -0.130860473889824 6.8600580178573e-06 58.6249609008445 14.8706519720077 3.9423262013797 9.40476922347275e-05 -84.0273694088206 43.261156865703 -1.94232830318591 0.0527439094543617 GPR19 other 0.0387318875688223 1 0.782570847085167 3.9423262013797 -1.94232830318591 2.25417716760335e-06 146.268500238443 144.078534760421 1.01519980392404 0.310572328972916 1140.14890185683 241.018568589221 4.73054382710253 3.02748333442857e-06 TMEM119 other 0.0132996452888598 0.0262210331594859 1 1.01519980392404 4.73054382710253 2.87708863416653e-11 56.0096624686433 20.807043358109 2.69186070815847 0.00737891910475194 -81.8503938868085 25.9077452079041 -3.15930210174512 0.00169153050504423 FANCF other 2.14602041222482e-07 1 1 2.69186070815847 -3.15930210174512 6.19373536895207e-18 327.299836235132 72.1009777390703 4.53946460226396 7.30102700499165e-06 -359.952888664517 108.899974190359 -3.30535329636821 0.00102674263085036 SMDT1 other 5.17610464783325e-14 1 0.0637452667805821 4.53946460226396 -3.30535329636821 0.228794525035624 -26.7741018350997 32.8031566667401 -0.81620504109126 0.414832699154309 -156.415237255408 94.5304257266487 -1.65465495424416 0.0987208153664255 C2CD4C other 1 1 1 -0.81620504109126 -1.65465495424416 0.333580917146408 -139.681911145852 110.986979433091 -1.25854322605527 0.208865779838514 74.4073463327217 256.15469840847 0.290478163371691 0.771587935818462 CHST6 other 1 1 1 -1.25854322605527 0.290478163371691 1.4523253924122e-61 889.264632900731 109.795136874135 8.09930802235944 5.5395793730925e-15 -155.133175365214 133.91118276848 -1.15847812078119 0.247300224544829 RUVBL2 essential 1.40817470048287e-57 1 5.37228407602511e-11 8.09930802235944 -1.15847812078119 5.22241075078046e-10 38.9215891848604 13.6620181044751 2.84889017766061 0.0045939449791836 -94.4425472055968 26.001301733027 -3.63222380845784 0.000314254034532844 GDPGP1 other 3.76222470486225e-06 1 1 2.84889017766061 -3.63222380845784 1.14305896592212e-07 158.591130050318 100.96429482791 1.57076449967418 0.116961095041675 -249.143188766503 122.605439544737 -2.03207288103717 0.0427506072240885 CTNNA3 other 0.000732815103052669 1 1 1.57076449967418 -2.03207288103717 0.0322832974079273 -2.81143460603346 2.15968934752491 -1.30177731776817 0.193679879181905 -9.29269046357798 3.54513728124732 -2.621249820912 0.00906706217665578 RIMBP3C other 1 1 1 -1.30177731776817 -2.621249820912 0.000512210056961135 11.3861363375103 7.57498928185619 1.50312243540498 0.133528119383116 -37.1076724746684 14.8853688322993 -2.49289573491451 0.0130389135192652 LINC01547 other 1 1 1 1.50312243540498 -2.49289573491451 0.150502047123777 244.407230716159 949.258397901195 0.257471760330529 0.796935529224082 -2955.63733926725 1865.3572756547 -1.5844886005711 0.113804282354569 PTTG1IP other 1 1 1 0.257471760330529 -1.5844886005711 0.00185132289154965 181.78288440633 107.67586481603 1.6882416938737 0.0920766522638333 -409.152942902006 206.496894651501 -1.98139997985211 0.0481712970045946 DDX41 essential 1 1 1 1.6882416938737 -1.98139997985211 1.97669158752204e-08 -205.264106869151 472.565970878221 -0.434360744358478 0.664240884934901 -3640.06720685212 715.132087128054 -5.09006276234997 5.32842290734822e-07 DAZAP2 other 0.000133031343840234 0.00474123070295845 1 -0.434360744358478 -5.09006276234997 0.67519663250126 -7.20927507397652 11.0068507234312 -0.654980725652027 0.512823983719175 -15.5711732521774 17.7227520915594 -0.87859792721432 0.380101040568899 CCBE1 other 1 1 1 -0.654980725652027 -0.87859792721432 4.70123708499993e-61 398.468569894367 127.772120350328 3.11858775452609 0.00193707128420338 -1290.51146546633 164.861412092895 -7.82785643458617 3.76735950121431e-14 SELENOF other 4.55549873536493e-57 3.64642726122533e-10 1 3.11858775452609 -7.82785643458617 2.78820587557398e-29 325.554235703349 30.2090575609556 10.77670943711 3.52554215162472e-24 -185.330886669479 88.6251823621396 -2.09117636466102 0.0370878680415081 ZNF623 other 2.51635580270552e-25 1 3.45820429652868e-20 10.77670943711 -2.09117636466102 1.33768166286064e-26 -45.1094264685024 29.1506005262192 -1.54746130968826 0.122474251919872 183.506657140205 37.4322112916033 4.90237287107237 1.33612245265454e-06 EPHA10 other 1.19361334777055e-22 0.0117378357465701 1 -1.54746130968826 4.90237287107237 1.5752850203825e-13 236.773504963554 69.5344227903836 3.40512648932637 0.000722558777248928 -231.607425432961 80.0880111490911 -2.89191131244104 0.00402063156378426 KIAA2026 other 1.23596862699211e-09 1 1 3.40512648932637 -2.89191131244104 0.0844289739505779 -21.441039853234 49.810697789459 -0.430450501694666 0.667079691335919 41.5440610484407 56.1263178697089 0.740188607150048 0.459582128399952 SYNDIG1L other 1 1 1 -0.430450501694666 0.740188607150048 1.60166062343623e-22 49.2413907232575 47.6912715363211 1.03250320524073 0.302406211097822 -293.138967254541 61.2402393325356 -4.78670512149358 2.32238353308483e-06 FHL3 other 1.39824972425983e-18 0.0202070591213711 1 1.03250320524073 -4.78670512149358 6.54517298788897e-05 14.5749453791453 4.14466032918231 3.51655967475162 0.00048279801076128 -16.1016504543619 11.4605214370645 -1.40496665381101 0.160740007522533 C19orf71 other 0.331709367026213 1 1 3.51655967475162 -1.40496665381101 0.000486068352487345 1.86149802890936 2.30303251122929 0.808281263869673 0.419367467103427 -7.90219635817538 3.23743890617136 -2.44087891299256 0.0150467253174095 LRIT3 other 1 1 1 0.808281263869673 -2.44087891299256 7.51044334789821e-89 346.001804598969 60.9158042953408 5.68000059428639 2.45804158374818e-08 -680.790830255621 78.2218278944285 -8.70333573864376 6.6016342589087e-17 SF3A3 essential 7.38652103265789e-85 6.44319503669489e-13 0.000227172203170007 5.68000059428639 -8.70333573864376 2.15666529335033e-08 31.3579068383464 18.2188933653936 1.72117516741769 0.0859268023677175 -137.181294633196 34.4010178157178 -3.98771034531769 7.8191057997788e-05 ASB7 other 0.000144841641101408 0.627248667258255 1 1.72117516741769 -3.98771034531769 1.92282683866793e-05 37.0462028562553 10.0309174200724 3.69320185829902 0.000249636521264237 -8.44917035677918 18.3844825492073 -0.4595816245665 0.646046145191147 SH2D7 other 0.103832649288068 1 1 3.69320185829902 -0.4595816245665 0.0761445360400153 21.7603905587447 15.1541533007098 1.43593575483531 0.151737682658469 39.4636680938757 17.7284472317961 2.22600815389502 0.0265240990052436 GPR132 other 1 1 1 1.43593575483531 2.22600815389502 0.127206350032349 -58.9766854592435 88.6012606037602 -0.665641606647079 0.505990587463098 237.90675861606 172.562001666623 1.37867407840851 0.16869897020409 MX2 other 1 1 1 -0.665641606647079 1.37867407840851 0.000250016976922442 288.341786260673 117.562800004715 2.4526617794839 0.0145693944633891 -488.889662447758 210.860990842823 -2.31854009835407 0.0208795490588287 EP400 other 1 1 1 2.4526617794839 -2.31854009835407 0.0617640997762721 69.9282158983519 36.0839253736008 1.93793261609813 0.0532767317779588 -12.7746298435364 70.7454844681359 -0.180571663895951 0.85678770066384 MEX3B other 1 1 1 1.93793261609813 -0.180571663895951 0.000487132175678314 72.8683631473868 65.7467159457194 1.10831943617605 0.268334889822189 -268.389837414938 107.923453938349 -2.48685366915939 0.0132609534609445 PI4KAP2 other 1 1 1 1.10831943617605 -2.48685366915939 0.00419323169227148 -2.53506466449815 45.6753517728354 -0.0555018093151465 0.955764170893107 -101.441040721807 57.4669174632622 -1.76520762204893 0.0782304574739646 FAM46C other 1 1 1 -0.0555018093151465 -1.76520762204893 4.99771686465706e-63 84.3113366640921 23.8790123320441 3.53077151984849 0.000458269449973796 -233.878503469979 30.6629784262564 -7.62739027562017 1.50539877988793e-13 UTP11 other 4.85228330389554e-59 1.45255928271386e-09 1 3.53077151984849 -7.62739027562017 6.41231984564954e-05 67.1750058726804 20.251896600803 3.31697357520662 0.000985811320061531 -40.7015168294236 39.443093598961 -1.03190478016906 0.302686171662125 PSMG1 essential 0.325553478563627 1 1 3.31697357520662 -1.03190478016906 4.75817392433984e-10 103.471951156879 54.3592240816478 1.9034846965708 0.0576355541841399 -347.498616496749 85.8464689233287 -4.04790809517287 6.11471404429075e-05 PRR14L other 3.43492575598093e-06 0.494313483340464 1 1.9034846965708 -4.04790809517287 5.30547427543927e-07 33.2937994402332 14.9608628367864 2.22539300062086 0.0265644793663379 -51.483244873372 22.1875242256222 -2.32036906641071 0.020780569843324 SERHL2 other 0.00327931364964901 1 1 2.22539300062086 -2.32036906641071 0.193541645109872 35.6449328355361 61.897056611223 0.575874440353809 0.564996489713513 -145.437835341209 118.850439536645 -1.22370464853322 0.221723048076427 PCBP3 other 1 1 1 0.575874440353809 -1.22370464853322 9.50775664726421e-26 -79.3312982513583 90.2845800055243 -0.878680481722396 0.380056314680419 -810.330174318687 106.876344170767 -7.58194136041876 2.0533222770322e-13 SETD3 other 8.44764178109425e-22 1.98001867174215e-09 1 -0.878680481722396 -7.58194136041876 0.273769174367103 26.5961674664147 53.401646993585 0.498040209688843 0.61870681576912 -72.5857114819572 82.2752817883416 -0.882229873957631 0.378138635527465 TNFAIP8L3 other 1 1 1 0.498040209688843 -0.882229873957631 0.0737864318832261 -6.22312894543413 85.8329515648234 -0.072502795627787 0.942234952139809 -261.241168220819 137.547830311804 -1.89927509309756 0.0581865485610943 ZNRF3 other 1 1 1 -0.072502795627787 -1.89927509309756 0.217218454675986 42.1070777952135 109.406828681314 0.38486699873063 0.700523624047392 -209.716503762527 183.829388987007 -1.14082141554281 0.254570485230981 FBXL7 other 1 1 1 0.38486699873063 -1.14082141554281 0.000547262227144402 7.13298715731713 31.6691419656644 0.225234620030145 0.821901806335585 -159.680010730179 52.5548766424553 -3.03834812165052 0.00252110215788151 TANGO2 other 1 1 1 0.225234620030145 -3.03834812165052 6.85367750129904e-20 113.260881406428 50.2229436748601 2.25516214540651 0.0246172170953402 -156.861280479331 56.9388675265822 -2.75490692550391 0.006116117176177 SFXN4 other 5.84481617310782e-16 1 1 2.25516214540651 -2.75490692550391 0.0117856188664578 3.42448256826865 3.36663192207384 1.01718353759302 0.309628939872861 -2.8090469024417 4.32487737381613 -0.649509028729545 0.516350649657993 FAM167B other 1 1 1 1.01718353759302 -0.649509028729545 0.0027219519143967 167.07070219587 56.8682890081831 2.93785350517279 0.00347979920604166 -121.268268468404 158.110207571086 -0.766985701501164 0.443504175280298 MRPL54 essential 1 1 1 2.93785350517279 -0.766985701501164 1.17139624230523e-27 127.770832379994 14.0329916853371 9.10503157452167 3.10087529422764e-18 -24.9520573418257 26.6491212532905 -0.936318203691043 0.349626516561848 ZNF438 other 1.05121098784471e-23 1 3.02397358693079e-14 9.10503157452167 -0.936318203691043 8.83618264586284e-09 164.99820763822 53.2053791838882 3.10115650276551 0.0020527528196053 -383.227186779856 108.706715597558 -3.52533129782521 0.000467728703855255 HMCES other 6.05013425762229e-05 1 1 3.10115650276551 -3.52533129782521 3.65284139948372e-05 -24.9907158273189 200.002891719217 -0.124951772509386 0.900619058161149 -1220.73415050498 326.306886320187 -3.74106156407358 0.000207610929136915 DGCR6 other 0.191262775676967 1 1 -0.124951772509386 -3.74106156407358 1.23286644968265e-60 80.9382399095385 7.85436931671485 10.3048681117266 1.95022005084866e-22 15.4219440149542 9.85141986354679 1.56545393745932 0.118200328899751 ZNF530 other 1.19415444316261e-56 1 1.91063058381644e-18 10.3048681117266 1.56545393745932 9.37671079028989e-09 228.864598664497 68.2090929163266 3.35533854621479 0.000861865872947788 -18.8148861732369 80.6133004014362 -0.233396797793204 0.815562587109608 NDUFB1 other 6.40898182516314e-05 1 1 3.35533854621479 -0.233396797793204 0.204191443918335 -0.315431642350851 6.37974378811857 -0.0494426818422239 0.960589207810023 -16.0147517628176 10.8661729937388 -1.47381711776957 0.14125410856341 MARCH11 other 1 1 1 -0.0494426818422239 -1.47381711776957 0.037939456842904 -16.4255507003392 152.807162681727 -0.10749202074088 0.914447987266734 -677.404809649218 299.57821613217 -2.26119515095302 0.0242380721365652 KLHL25 other 1 1 1 -0.10749202074088 -2.26119515095302 0.255111756315913 -39.3254081924958 37.4990378644529 -1.04870445835556 0.294892475034552 29.7914637639641 62.519078067297 0.476517963554994 0.633943040052452 FAM19A1 other 1 1 1 -1.04870445835556 0.476517963554994 0.0336590324075 54.7195863036112 24.8130222490692 2.20527696119984 0.0279619498881157 -0.94605196525191 49.1788958423532 -0.0192369500991758 0.984660983244292 GUSBP1 other 1 1 1 2.20527696119984 -0.0192369500991758 7.93033648792346e-14 2.02892874592191 5.1055172937924 0.397399250490993 0.691266656494062 -25.9916258202126 6.55598164855231 -3.964566591786 8.58553721529845e-05 BMP8A other 6.25307032072764e-10 0.686928832596029 1 0.397399250490993 -3.964566591786 7.62589778203086e-13 651.152117915353 84.866218175266 7.67268922683218 1.11210716762233e-13 162.933595011428 223.801285514915 0.728027967473716 0.466987263916009 ALYREF essential 5.88948085706243e-09 1 1.07451794535669e-09 7.67268922683218 0.728027967473716 0.000759814419547805 -21.8707011399218 58.5238777273127 -0.373705605117737 0.708805839838706 158.916465221713 41.6243599715619 3.81787168211802 0.000154196860199737 RFLNB other 1 1 1 -0.373705605117737 3.81787168211802 0.00156804820233307 170.56522002667 64.2776594602268 2.65356924099284 0.00825623556137015 -138.282963591547 130.043002314197 -1.06336335774102 0.28820714149802 TRIM52 other 1 1 1 2.65356924099284 -1.06336335774102 0.0056656093133747 -327.987600252707 220.070620724236 -1.49037431336052 0.136845602483343 -1632.1145995067 507.916548122346 -3.21335188928234 0.00140884742807775 CMTM4 other 1 1 1 -1.49037431336052 -3.21335188928234 3.05719088895335e-54 164.642888792755 74.2739390427469 2.21669795509294 0.0271578629390864 -741.798768431063 95.4065082682522 -7.7751380057361 5.45949952744274e-14 TMEM50A other 2.93948903972865e-50 5.27988199298987e-10 1 2.21669795509294 -7.7751380057361 0.000122514979573344 38.267354254214 28.755117492037 1.3308015265391 0.183949856780798 -123.700674796671 46.8062169507353 -2.6428257367364 0.00851777728586513 TBK1 other 0.600445914888959 1 1 1.3308015265391 -2.6428257367364 6.34118990419305e-07 507.501858736061 289.423281604866 1.75349355422252 0.0802167869830463 -1350.68463444857 452.962019085978 -2.98189379580673 0.00302452546626443 CBX6 other 0.00390046591006914 1 1 1.75349355422252 -2.98189379580673 0.379530527322897 -43.6905192992253 59.3647068897727 -0.735967910704067 0.462145074263302 -132.262904746021 95.1323061938239 -1.39030482953442 0.165144010939193 KREMEN1 other 1 1 1 -0.735967910704067 -1.39030482953442 0.0147610683034835 48.4997431192662 16.6618196411601 2.91083111951686 0.00379029345244346 48.3125680095733 25.4856925889092 1.89567412543451 0.0586672270672377 TRAIP essential 1 1 1 2.91083111951686 1.89567412543451 8.54123320357109e-06 61.9988550347704 13.3033117639616 4.66040758382616 4.19687078958772e-06 84.0709360212222 21.3186385383994 3.94354151039206 9.34924033079635e-05 CHEK2 ts 0.0478223647067945 0.746162870800856 0.0369744316562678 4.66040758382616 3.94354151039206 2.25124152967625e-07 -226.115067785094 104.862478127026 -2.15630101275298 0.0316063935460859 541.906540264569 177.346947193012 3.05562936854388 0.0023837671459208 AIFM3 other 0.00142233439844946 1 1 -2.15630101275298 3.05562936854388 0.737502950182945 -10.1071298211508 74.7435646502008 -0.135224080741293 0.892496970614193 -112.266567303407 148.009990872353 -0.7585066835132 0.448556595264906 KCTD16 other 1 1 1 -0.135224080741293 -0.7585066835132 0.0397952716511622 42.1063542400752 20.5651942062095 2.04745716562995 0.0412092203811528 -14.6840665794152 40.0532797468543 -0.366613337839543 0.714084492478329 B3GALT5 other 1 1 1 2.04745716562995 -0.366613337839543 0.42909282557978 -19.6057654520795 15.2482640326917 -1.28577032834986 0.1992025709837 -18.6929782675752 34.2141699031928 -0.546351944836481 0.585102226067559 SLC35F3 other 1 1 1 -1.28577032834986 -0.546351944836481 0.249196725227562 3.31351351351256 16.5178905922473 0.200601492969554 0.841103516075351 -34.1063063063068 26.8901291170816 -1.26835784825746 0.205345451095481 KCTD8 other 1 1 1 0.200601492969554 -1.26835784825746 0.541170689788605 -19.7158863508238 46.6188839505974 -0.422916309444837 0.672563880886575 -82.6013976915792 76.6929941309231 -1.07703967784293 0.282055385209331 TUBA8 other 1 1 1 -0.422916309444837 -1.07703967784293 0.177220569953818 13.6936076956644 19.0448379633689 0.719019385830581 0.472513271796486 -15.098181969864 23.0486216386362 -0.655057912207431 0.512775122505292 OLFML1 other 1 1 1 0.719019385830581 -0.655057912207431 0.0136234855118408 -4.22338343236626 3.27994665492302 -1.28763784192258 0.198553541144798 -11.3202776252059 4.25136481701454 -2.66273964066801 0.00803683721528833 FAM162B other 1 1 1 -1.28763784192258 -2.66273964066801 0.0067379574271648 8.49353292905204 65.3133437204574 0.130042843395135 0.896592230769022 -442.762789251236 153.340980769093 -2.88743939832996 0.00407623032447198 BTBD9 other 1 1 1 0.130042843395135 -2.88743939832996 0.204847408189171 37.0017593933355 35.3657608826162 1.04625938958727 0.296020968939766 -4.93803453499973 41.1186208534884 -0.120092416343307 0.904465258250494 NUDT14 other 1 1 1 1.04625938958727 -0.120092416343307 0.777462421142627 -3.06376229727351 37.6754638024987 -0.0813198296199957 0.935224749776333 -49.8405104246442 74.8311309660884 -0.666039785597129 0.505736297870128 MAATS1 other 1 1 1 -0.0813198296199957 -0.666039785597129 1.47717619647353e-07 247.352135374689 252.044899376381 0.981381237972667 0.326947773646088 -1416.84842868655 382.743271373391 -3.70182452483751 0.000241422546309655 TOB2 other 0.000942438413350111 1 1 0.981381237972667 -3.70182452483751 0.00291725121957194 3.82915545341857 9.14466417242065 0.4187311180838 0.675618371697579 47.9314051585982 15.5570999085239 3.08099873629636 0.00219341152866228 SCN5A other 1 1 1 0.4187311180838 3.08099873629636 0.828578661342781 -9.21790692446043 32.2816116645973 -0.285546676548667 0.775360643605681 -38.100213579137 62.1860059320587 -0.612681470824213 0.540405668640838 ARSI other 1 1 1 -0.285546676548667 -0.612681470824213 0.22569083089177 -30.6291768328482 20.2711176006674 -1.51097622914682 0.131515600497555 -12.2158638694395 15.2770479630626 -0.799622014604881 0.424363262362213 DNAH2 other 1 1 1 -1.51097622914682 -0.799622014604881 7.03263479683073e-05 111.722986266097 26.3202124133212 4.24476005404698 2.67551864317014e-05 29.0731929199419 53.2330186344112 0.546149620400226 0.585242438858304 KMT5A other 0.355359036283857 1 0.228355516194572 4.24476005404698 0.546149620400226 0.0956956745908584 104.297733973062 61.5599867491934 1.69424555593214 0.0909294960668104 -62.7836002081045 126.836636851239 -0.494995781713611 0.620851311679712 KCNH8 other 1 1 1 1.69424555593214 -0.494995781713611 0.239497823966354 105.984726894532 64.0045855942087 1.65589271316401 0.0984630456921634 70.6763083896148 101.078846524941 0.699219577779564 0.48478765616336 SMTN other 1 1 1 1.65589271316401 0.699219577779564 0.0023215669526903 -5.41051505867375 7.16739120231215 -0.754879272799894 0.450727119148349 -50.4367400813148 14.7675112212454 -3.41538525521847 0.000696289581324124 PP2D1 other 1 1 1 -0.754879272799894 -3.41538525521847 5.54779288118021e-06 267.732207478889 75.7233987204865 3.53566020546904 0.000450207634854563 -413.336147969441 165.85521421251 -2.49215045744557 0.0130667618677819 COA3 other 0.0316446105942519 1 1 3.53566020546904 -2.49215045744557 0.0053502024927623 23.777321621236 7.61449453824853 3.12263952673413 0.00191173803555031 -5.53402357606132 20.0802357268582 -0.275595548346044 0.782989296334385 NPB other 1 1 1 3.12263952673413 -0.275595548346044 0.432961937974955 12.7828881453004 28.4434265043531 0.449414494535111 0.653354978899424 -9.91917306096247 36.5262681949212 -0.271562728719757 0.786086208654955 ST6GALNAC3 other 1 1 1 0.449414494535111 -0.271562728719757 1.28085123512366e-49 273.454655611003 239.272700155527 1.14285773275956 0.253723393404472 -2521.72700498754 307.376960424315 -8.20402089182757 2.62483456018115e-15 PTP4A2 other 1.22206016343148e-45 2.55081422558404e-11 1 1.14285773275956 -8.20402089182757 9.21095207928594e-06 10586.6158613974 2300.01583361357 4.60284477466604 5.47380073693776e-06 -4091.81443802213 6065.38751620015 -0.674617149702838 0.500276584279757 ACTG1 other 0.0514339564107327 1 0.0480052324629441 4.60284477466604 -0.674617149702838 1.27023782715984e-15 1041.02526241491 544.693597398617 1.91121259252305 0.0566326688805762 -2900.98439660023 659.819117730592 -4.396635863747 1.38291565592243e-05 DENND5A other 1.03206823456737e-11 0.116192573410602 1 1.91121259252305 -4.396635863747 0.000129543969490061 167.168323699423 81.4832671055949 2.05156628639826 0.0408059569543327 -417.943052023121 162.420400188456 -2.57321772103862 0.0104038227326357 DIABLO other 0.632822290958949 1 1 2.05156628639826 -2.57321772103862 2.01731954190443e-13 85.4897139710915 21.7675995807749 3.92738361682269 9.97680155783485e-05 -161.461770120185 42.1779248304382 -3.8281108131632 0.000147987535876485 VPS33B other 1.57714041786088e-09 1 0.829171977471654 3.92738361682269 -3.8281108131632 0.0931541377827673 42.4566879534292 54.0938711203741 0.784870579126259 0.432955703823334 244.557300490898 112.271726009887 2.17826258829727 0.0299215873820777 ADAP2 other 1 1 1 0.784870579126259 2.17826258829727 0.000101970928960844 222.922204548133 79.4176880508438 2.80695912987818 0.00522434674656189 -140.598513412671 129.194563408155 -1.0882695811935 0.277074563055385 UQCR10 other 0.50506201114306 1 1 2.80695912987818 -1.0882695811935 0.951084106349858 41.8991499783982 302.451884165377 0.138531621629734 0.889884093156792 156.686087499408 501.959906877702 0.31214861058133 0.755076468581674 CLDN5 other 1 1 1 0.138531621629734 0.31214861058133 4.66592572668131e-05 19.8967047641487 102.121933807084 0.194832824080036 0.845614164347397 -595.017484256968 166.129221038972 -3.5816545730831 0.000379688534260069 NIPSNAP1 other 0.240901745268556 1 1 0.194832824080036 -3.5816545730831 0.501273256807343 -0.0422062853608188 8.23535178488895 -0.00512501304901912 0.995913182478141 -12.7681775990101 13.199072207922 -0.967354174435587 0.333900840156825 ADRA2C other 1 1 1 -0.00512501304901912 -0.967354174435587 7.7180842939189e-05 2.44176869881042 3.05586546043346 0.799043259733062 0.424701389705758 -7.36657759453079 4.05890430759024 -1.81491777984396 0.0702251149108708 C1QTNF12 other 0.387833735769425 1 1 0.799043259733062 -1.81491777984396 1.30037886647992e-05 133.578632513852 51.4676850511166 2.59538839528501 0.00976565401027227 -98.3322819779963 75.5739381673138 -1.30114010679578 0.193894535374487 CRELD2 other 0.071481826290401 1 1 2.59538839528501 -1.30114010679578 0.386883307454935 30.5147508277442 54.4541891741168 0.560374716629672 0.575525526188789 -73.0204601409282 93.8701960003892 -0.777887585753262 0.43707746363598 SCFD2 other 1 1 1 0.560374716629672 -0.777887585753262 1.16935155603692e-09 82.1421968130404 32.7692651570562 2.50668412670684 0.0125490700140853 -131.633019590567 49.8704225058687 -2.63950078977327 0.00859974379015981 UBE2F other 8.30941215719833e-06 1 1 2.50668412670684 -2.63950078977327 0.128721239773643 -15.4435488497498 13.9092398849031 -1.11030861337808 0.26748226221623 -17.3067523377889 10.3192928108179 -1.67712581230818 0.0942395739559774 KCNJ12 other 1 1 1 -1.11030861337808 -1.67712581230818 6.19879436428427e-10 44.7208029524014 50.9610162081391 0.877549277466311 0.380669454227302 -448.633753739763 89.3257278866472 -5.02244722045894 7.44065784473443e-07 PPP1R2 essential 4.45259399186539e-06 0.00659167878465024 1 0.877549277466311 -5.02244722045894 1.01595585931973e-08 -51.9782433521357 90.2934919132506 -0.575658801656201 0.565142134539252 -701.368896051571 137.115357478418 -5.11517388679068 4.70113036450594e-07 C22orf46 other 6.93389873985719e-05 0.00419481862424865 1 -0.575658801656201 -5.11517388679068 3.7373605481286e-06 204.399839475233 40.3238768406158 5.06895307420821 5.92287174080931e-07 156.912710327863 74.9704161034442 2.09299505702829 0.0369269797677971 SNRNP35 essential 0.0216692164580496 1 0.00534124573586183 5.06895307420821 2.09299505702829 0.00134860835844986 60.4917484200002 33.2569925597847 1.81891818122931 0.0696097548381119 -126.097900676055 64.3953945288668 -1.95818197246277 0.0508459353557619 CMSS1 other 1 1 1 1.81891818122931 -1.95818197246277 0.654679850742447 950.763556173278 1914.73266810857 0.496551592819729 0.619756123596698 -1772.18125618874 3825.04417022172 -0.463310010897472 0.643373886041276 OLIG1 other 1 1 1 0.496551592819729 -0.463310010897472 2.58129052254724e-07 -912.472656250013 355.47941360715 -2.56687904087299 0.0105952956175628 -2134.53292410715 417.430415755086 -5.11350597259668 4.74897853731727e-07 PCDH9 other 0.00162466425489123 0.00423656375314073 1 -2.56687904087299 -5.11350597259668 8.39368061068724e-05 -46.9245200507285 43.5522329000566 -1.0774308669411 0.281880862418624 -157.765404294398 49.9728606023067 -3.15702167922554 0.00170399877793548 ACOT1 other 0.419432220116041 1 1 -1.0774308669411 -3.15702167922554 0.82314723911291 18.111371997404 98.5228275533723 0.183829194179315 0.854232719783741 -75.3575308374798 186.031361946293 -0.405079713705668 0.685617139397036 ALDH1A3 other 1 1 1 0.183829194179315 -0.405079713705668 5.37141911213874e-12 136.384334622956 91.4407888597999 1.49150435296512 0.136550621925305 -676.158417889391 138.376959442126 -4.8863511715777 1.44447882001372e-06 POU6F1 other 4.07314711273481e-08 0.0126753016456204 1 1.49150435296512 -4.8863511715777 3.10062444265474e-16 197.594046865102 62.3817073403547 3.1674998214946 0.00164611682033921 -610.536632112267 116.929891624381 -5.22139055831439 2.76023956110438e-07 TM2D3 other 2.54158185564409e-12 0.0024778670540034 1 3.1674998214946 -5.22139055831439 1.80799386613195e-14 535.977225391268 99.3205910699239 5.39643612283709 1.11677763914014e-07 56.0836752216703 113.493119859113 0.494159252043567 0.621442013394471 TSSC4 other 1.44115191069377e-10 1 0.00102118147322975 5.39643612283709 0.494159252043567 0.142443721705996 22.1363262367582 18.3649056588762 1.20536019340013 0.228715074387122 39.3841921217731 21.0971528012293 1.86680129270705 0.0625972406256242 SIX6 other 1 1 1 1.20536019340013 1.86680129270705 2.23293845961724e-08 206.283324988936 74.2512211881401 2.77818090649645 0.00570352479324621 -206.837545440691 102.918785076867 -2.00971615906863 0.0450796985382775 PRKD1 other 0.000149740853101932 1 1 2.77818090649645 -2.00971615906863 0.6838432622047 -5.09435235158036 7.52344699465782 -0.677130091459102 0.498681705454429 -0.658968248405198 10.8659012890021 -0.0606455213312281 0.95166924422278 CCSER1 other 1 1 1 -0.677130091459102 -0.0606455213312281 0.537706150064627 -9.56350330500445 41.3697008155449 -0.231171681604497 0.817289377560762 68.5197288547157 80.0986788759556 0.855441435692446 0.39277450978082 ZDHHC23 other 1 1 1 -0.231171681604497 0.855441435692446 8.48489699953786e-11 29.3407224700152 20.0504196912809 1.46334704818045 0.144089677998442 -62.4513099759912 25.7466924461572 -2.42560515711261 0.0156860157808834 MROH7 other 6.25846002685913e-07 1 1 1.46334704818045 -2.42560515711261 0.923220625597435 14.1701819382299 87.7889062678684 0.161411988605858 0.87184352173565 -35.7595921062286 156.538475388075 -0.228439634521653 0.819411336488653 SLIT3 other 1 1 1 0.161411988605858 -0.228439634521653 4.26872829428349e-38 0.470083765459539 190.782708098325 0.00246397469742 0.998035156429748 -2072.60384552882 253.737719308039 -8.16829224752614 3.37811112825451e-15 CSF1 other 3.96607545821879e-34 3.2811593388736e-11 1 0.00246397469742 -8.16829224752614 4.14713139076727e-16 98.5963379626898 61.6732967801399 1.59868765106197 0.110612760575672 -548.698041399292 95.3147808643289 -5.75669414988541 1.61750884300606e-08 PLA2G6 other 3.39318290392578e-12 0.000148924039175568 1 1.59868765106197 -5.75669414988541 0.157827082739981 -4.74340800057718 5.11918776511021 -0.926593869618505 0.3546477131074 -19.6837824189302 10.2259472401805 -1.92488597453225 0.0548909475888166 UMODL1-AS1 other 1 1 1 -0.926593869618505 -1.92488597453225 8.88299907539255e-21 238.225490481319 24.1190393850259 9.87707207896591 6.6201306634221e-21 66.4893812751889 75.6947836481043 0.878387889769127 0.380214848036267 TOP1MT other 7.64826220391299e-17 1 6.47647382802584e-17 9.87707207896591 0.878387889769127 6.82424533611687e-12 400.291517834988 62.4521948290242 6.40956685238795 3.79426494941384e-10 65.4082286876174 105.621250768211 0.619271483833854 0.536060974533725 THAP7 other 5.15912947410436e-08 1 3.59203062761008e-06 6.40956685238795 0.619271483833854 0.0180890426344851 115.066251709342 51.1818393724341 2.24818515942815 0.0250621062094349 -66.6828081529646 101.254284992399 -0.658567764889858 0.510520185956437 KNTC1 other 1 1 1 2.24818515942815 -0.658567764889858 0.337414959647973 4.88169592994735 8.65320443380935 0.564148919315235 0.572942202772952 -22.2309453603177 18.9529141486595 -1.17295657997216 0.241452174662129 CCR10 other 1 1 1 0.564148919315235 -1.17295657997216 2.69721601962477e-06 -4.592689283652 6.71480723352479 -0.683964427261923 0.494359322138905 -28.4429876820177 8.62168351863979 -3.29900623474811 0.00104947219786173 NCMAP other 0.0158083830910208 1 1 -0.683964427261923 -3.29900623474811 4.82748426830687e-08 120.486339925143 44.7595460754797 2.69185794963072 0.00737961303908959 -67.5657658188675 57.8062093695809 -1.16883232019054 0.243111314936964 WDR27 other 0.000317020891899712 1 1 2.69185794963072 -1.16883232019054 3.11670484223936e-09 167.432459749853 52.7458974900876 3.17432194193526 0.00160777885344628 -233.105168529281 87.5317095421344 -2.6630939775839 0.00802785866872258 TXNRD2 other 2.17545997988307e-05 1 1 3.17432194193526 -2.6630939775839 0.0044726380044512 347.295762900533 227.06123016464 1.52952471299795 0.126859584893847 -257.107866838494 307.304985295151 -0.836653745111082 0.40324554441553 POU3F2 other 1 1 1 1.52952471299795 -0.836653745111082 9.60216795149706e-05 232.219650200644 55.6827672569732 4.17040426760692 3.66692233875883e-05 441.161301232914 198.536678417587 2.22206448072537 0.0267891191287206 PTP4A3 other 0.476939682150859 1 0.310845006656586 4.17040426760692 2.22206448072537 0.39065360012276 1.07246976580776 10.9469934468671 0.0979693439128432 0.922002714534194 17.3153317573643 15.4744203983943 1.11896480201359 0.263785697612935 TMEM255B other 1 1 1 0.0979693439128432 1.11896480201359 0.23157389885636 106.067224771193 184.169264064019 0.575922509709995 0.564970257248397 688.178985803164 402.294832998242 1.71063341946073 0.0878734336765844 PROS1 other 1 1 1 0.575922509709995 1.71063341946073 1.86890409580826e-07 57.1316967637521 21.1052629465412 2.7069881530718 0.00705572800354327 -116.512318764009 40.8945502136142 -2.84909158201771 0.00459156976023618 HDDC3 other 0.00118563275838076 1 1 2.7069881530718 -2.84909158201771 3.77638803458041e-05 78.1798712910512 27.5766525054214 2.83500222790571 0.00479464001093936 -149.390652717841 63.6461064326908 -2.34720803975385 0.0193590954992008 ZFP1 other 0.197380124422978 1 1 2.83500222790571 -2.34720803975385 2.26375364910714e-05 531.899803889175 308.276432393392 1.72539885634338 0.0851609502907826 -436.835881497018 357.791639352002 -1.22092255226582 0.222772169390842 CEND1 other 0.121201370373196 1 1 1.72539885634338 -1.22092255226582 0.0771495309347006 42.7312583262648 106.26642704269 0.402114379070056 0.687796003694601 -123.871211316068 122.578982079328 -1.01054201311529 0.31279359782536 DUSP8 other 1 1 1 0.402114379070056 -1.01054201311529 0.155687458402788 286.206735180486 160.307605348942 1.78535968120476 0.0748948200749431 445.195190734982 450.516049667757 0.988189413148102 0.32360546483291 SOCS3 other 1 1 1 1.78535968120476 0.988189413148102 9.58859907069565e-11 639.626241260869 203.722388687342 3.13969537360236 0.00180620053138498 -1134.65572890831 331.609645666109 -3.42166081034557 0.00068110370197025 XPOT other 7.06200321556735e-07 1 1 3.13969537360236 -3.42166081034557 5.9067532405497e-05 541.357919422231 401.438537265573 1.34854496807837 0.178180034618904 1762.16560363146 515.516359243677 3.41825350841778 0.000689182725904395 PDE4B other 0.301244415268035 1 1 1.34854496807837 3.41825350841778 0.133901699824514 142.465947403908 468.148531468501 0.30431783467742 0.761032976045594 -949.315933521083 708.255278788991 -1.34035843000601 0.180836593679033 NELL2 other 1 1 1 0.30431783467742 -1.34035843000601 0.000163990000150641 21.057658690357 8.89950204961271 2.36616145183914 0.018407993460297 -24.8910438179102 6.93747184145594 -3.58791277092758 0.000370948081000178 KRBA2 other 0.791415740726995 1 1 2.36616145183914 -3.58791277092758 0.214405742983752 4.13484768365126 3.96332950618683 1.04327628505192 0.297397135105513 -1.76747073063926 4.96111554741351 -0.356264778303891 0.721814220113904 OR7E14P other 1 1 1 1.04327628505192 -0.356264778303891 1.9944414083286e-41 9.06696748443689 47.0550086231568 0.192688679690834 0.847292923481905 -484.961730212281 60.5195320884051 -8.01330931481532 1.0411912535429e-14 ZBTB40 other 1.86899104374473e-37 1.0095390394352e-10 1 0.192688679690834 -8.01330931481532 9.7887201075707e-24 91.2764245910491 39.9065395857781 2.28725480932399 0.0226592211264821 -457.061185511412 63.02215618903 -7.25238889225707 1.88291656671026e-12 EIF4ENIF1 other 8.60330610254388e-20 1.80759990404185e-08 1 2.28725480932399 -7.25238889225707 2.77592620972582e-11 25.6914970519799 36.2663406040215 0.708411618709913 0.479069113343992 -276.087085187612 54.8378702166957 -5.03460626929227 7.0255972568526e-07 SERINC4 other 2.07139613769741e-07 0.00622889452792552 1 0.708411618709913 -5.03460626929227 1.29585294093057e-06 -3.93593410348324 7.74850092520747 -0.507960719302341 0.611737769534244 24.1743814931406 9.38503335819557 2.57584396032329 0.0103278406410792 RNLS other 0.00777770935146526 1 1 -0.507960719302341 2.57584396032329 2.6472070716147e-06 13.8617571059432 49.9910733880818 0.277284646367444 0.781692368013611 -335.324517041962 82.8991076872506 -4.04497136817232 6.18441952666658e-05 NDUFA12 other 0.0155417527174499 0.499701097754659 1 0.277284646367444 -4.04497136817232 2.39756728826639e-11 30.2461465916126 12.9239244325087 2.34032214824251 0.0197182599971511 -40.004258642539 16.6910334694281 -2.39675144836372 0.0169622994111219 TCTE3 other 1.79050325087734e-07 1 1 2.34032214824251 -2.39675144836372 1.64977385229957e-06 574.000344867235 152.164850331444 3.7722269211119 0.000184029747145321 -428.43762008769 299.014273976653 -1.43283333731801 0.152618811630091 UBE2G2 other 0.00983265215970543 1 1 3.7722269211119 -1.43283333731801 0.775980884222224 1.78339622641517 77.2967845591738 0.0230720622673496 0.981603321986578 72.199323899371 122.887227805336 0.58752504380472 0.557154583272802 OSBP2 other 1 1 1 0.0230720622673496 0.58752504380472 0.663783269850292 7.99383368569414 11.0047405513977 0.726399104854757 0.467982142048751 -2.83590053357493 21.4331042744831 -0.1323140361404 0.894796666324771 B3GALT5-AS1 other 1 1 1 0.726399104854757 -0.1323140361404 0.365418140039885 2.64790691107191 36.2719279164118 0.0730015486679941 0.941838209696781 -58.4235867321971 56.886110923746 -1.02702726172496 0.304974464514559 ZBTB7C other 1 1 1 0.0730015486679941 -1.02702726172496 0.132325683807387 204.510810484359 190.397943826816 1.07412299930287 0.283358932811598 -364.462124480183 365.138317815632 -0.998148117295675 0.318758646593358 TMED9 other 1 1 1 1.07412299930287 -0.998148117295675 0.316445761091306 -5.81060514554931 18.2691145349304 -0.318056199956461 0.750593893119721 -51.147291770918 35.0358497323544 -1.4598558950801 0.145046531251409 DRD1 other 1 1 1 -0.318056199956461 -1.4598558950801 7.73584015014986e-07 64.6758397294781 84.1736996743824 0.76836161389686 0.44268834477546 -276.301728423994 97.8660251149189 -2.82326505137556 0.00497143076662377 BTBD6 other 0.00472659833174157 1 1 0.76836161389686 -2.82326505137556 6.34255555500849e-05 824.388666758589 258.025643494791 3.19498734929124 0.00149990118978099 -742.455200803607 527.185797272902 -1.40833687979509 0.159744001809425 H1FX other 0.322201822194431 1 1 3.19498734929124 -1.40833687979509 0.0525515585432669 191.750201172549 109.434299336051 1.75219471715831 0.080440083208609 -143.564802194014 215.045836754266 -0.667600937366977 0.504739948767883 SUMO3 other 1 1 1 1.75219471715831 -0.667600937366977 0.00162777907214219 28.7493224410535 48.6836952153165 0.590532873766093 0.555139415588437 -103.255071857239 56.6029502927891 -1.82419946881096 0.0688062243335733 JAG2 other 1 1 1 0.590532873766093 -1.82419946881096 0.0158531035727737 -41.5357401375334 64.6142909339648 -0.642825906423435 0.520674199328145 402.889359391966 150.033603096394 2.68532749382228 0.0075216534697191 FMNL1 other 1 1 1 -0.642825906423435 2.68532749382228 1.2142589669662e-19 35.7546851651302 14.9321001794777 2.39448468302339 0.0170641577680067 -63.1856435847152 17.9528388682408 -3.51953493530725 0.000477670303533256 NUTM2A other 1.03345580678493e-15 1 1 2.39448468302339 -3.51953493530725 0.353647614239763 -9.07281702861352 10.3390248049201 -0.877531217866506 0.380681453528966 -30.5234769489716 21.7871560122057 -1.40098491661195 0.161929921467659 LCN12 other 1 1 1 -0.877531217866506 -1.40098491661195 5.72203446792533e-06 162.666952900264 46.4259541890588 3.50379342205528 0.000505985348708713 -222.403972206716 107.15154580515 -2.07560208801044 0.038515083759434 ZFP90 other 0.0325755422258989 1 1 3.50379342205528 -2.07560208801044 0.706634758349893 -4.99582629379338 20.7053892736353 -0.241281447442028 0.809450416959994 -25.0322559132135 32.2075677782322 -0.777216587280826 0.437452482032564 FAM227A other 1 1 1 -0.241281447442028 -0.777216587280826 0.0032394913473332 4.47766276121179 4.3195055719901 1.03661465104878 0.30048743208296 -5.57167942544394 5.01330240457778 -1.11137908225051 0.267014892984818 MUC6 other 1 1 1 1.03661465104878 -1.11137908225051 4.9653586077023e-07 190.420903397835 35.1207182048476 5.42189662202157 9.76411601943645e-08 159.152174933575 63.4912910012782 2.50667725326881 0.0125484791168771 NOC4L essential 0.00307206737058541 1 0.000893416615778436 5.42189662202157 2.50667725326881 0.784763619169695 -2.85129082021423 35.7278437909212 -0.0798058465800494 0.936428123632819 -35.5857387134546 58.7760813208517 -0.605445921431819 0.545196322484145 USP18 other 1 1 1 -0.0798058465800494 -0.605445921431819 2.10976268185314e-08 168.320117221171 63.9781369997391 2.63090057189158 0.00881686847295197 -240.511315782991 96.631386792463 -2.48895647435488 0.0131830408487589 NDUFA6 other 0.000141762266114609 1 1 2.63090057189158 -2.48895647435488 0.590675858942087 -1.59274679903455 15.1938359659924 -0.104828484564367 0.916560003560446 18.4060354425689 24.35121222336 0.755857050307831 0.450142139637438 CHRM5 other 1 1 1 -0.104828484564367 0.755857050307831 0.194876466824814 -73.1450644434478 103.007508784631 -0.710094490260706 0.478024287448104 -289.873238517374 163.619721180811 -1.77162775016004 0.0771532025427244 SORCS2 other 1 1 1 -0.710094490260706 -1.77162775016004 1.80880666754865e-06 14.7197841762145 50.4379133020833 0.29183967401773 0.770547697937514 -180.962240700733 58.5647526669135 -3.08995142060881 0.00212974699609014 TMEM121 other 0.0107533556385767 1 1 0.29183967401773 -3.08995142060881 0.0188231001972362 13.9268817204296 18.434045900983 0.755497832393214 0.450357341184882 118.006451612904 41.7069264711359 2.82942095228649 0.00487800937455348 TMEM106A other 1 1 1 0.755497832393214 2.82942095228649 2.31212875443249e-08 213.664980884171 58.4070273374064 3.65820673683439 0.000285504243819496 -12.0432348144088 68.3778274684674 -0.176127777969585 0.860276474963903 SIVA1 other 0.000154912626546977 1 1 3.65820673683439 -0.176127777969585 0.0188807924346919 -32.1758254325876 64.8528008419049 -0.496136250322083 0.620047155381378 -332.286239549861 119.41859267384 -2.782533541133 0.00562675210855534 BRI3BP other 1 1 1 -0.496136250322083 -2.782533541133 0.309951547446979 155.176204775479 164.373537350665 0.944046148039239 0.345667704627324 402.094386197069 264.237709719821 1.52171462060968 0.128803839118538 ROBO2 other 1 1 1 0.944046148039239 1.52171462060968 1.46865125853972e-12 229.239217995526 111.819582559951 2.05008114631998 0.0409513175870502 -364.45056530444 135.558442440808 -2.68851248762007 0.00745082000347138 AP3M1 other 1.12660238042582e-08 1 1 2.05008114631998 -2.68851248762007 0.704761824289242 37.9151833754476 85.9316651295667 0.441224818793859 0.659268464710173 -38.0355431914735 133.640099230065 -0.284611755084037 0.776076424984341 MAFF other 1 1 1 0.441224818793859 -0.284611755084037 1.47665927413302e-25 309.480438092049 87.0238552219297 3.55627129254165 0.000417255862157525 -420.861228656817 101.045626663209 -4.16506129512732 3.75205459456085e-05 BRF1 essential 1.31053510579305e-21 0.308043682213446 1 3.55627129254165 -4.16506129512732 0.00734647868667992 167.947346792548 210.126698326709 0.799267052354387 0.424568793470906 -864.572083368452 399.909269888018 -2.16192058666344 0.0311652023603771 SEMA4B other 1 1 1 0.799267052354387 -2.16192058666344 1.72095297985313e-06 293.076166441877 111.792765276 2.62160226306519 0.00905643271148531 -520.960565413469 212.761935995285 -2.44856093725812 0.0147339801433727 CIB1 other 0.0102431121360858 1 1 2.62160226306519 -2.44856093725812 0.305686484886004 -70.7162902808421 177.281162771841 -0.398893425421927 0.690166578640046 -451.862220137192 308.196700226417 -1.46614879330386 0.143326936619216 ANKS1B other 1 1 1 -0.398893425421927 -1.46614879330386 0.000380003118117603 -32.9977220742299 108.613122399922 -0.30380971787856 0.761417793422637 -311.469346837731 126.116514626718 -2.46969516846881 0.0139047987654476 FLRT2 other 1 1 1 -0.30380971787856 -2.46969516846881 0.00106546700436672 -26.0726902085358 103.697526019876 -0.251430204839587 0.801599707311067 -535.810455771054 171.969111008805 -3.11573661472042 0.0019557623162239 RPS27L other 1 1 1 -0.251430204839587 -3.11573661472042 2.24445968632409e-32 12.2664817412409 69.1709666402741 0.177335699312013 0.859326688434999 -611.925008887278 88.8222606664428 -6.88932036063866 1.9582536894007e-11 MANEAL other 2.05076281539432e-28 1.86464916304735e-07 1 0.177335699312013 -6.88932036063866 0.0794632875104642 -26.0548651403139 20.0805988023682 -1.29751435187486 0.195149918534151 -50.9912803148035 23.5086047512723 -2.16904749789729 0.0306264087759385 ADSSL1 other 1 1 1 -1.29751435187486 -2.16904749789729 2.63092727280447e-44 140.437433017001 43.2806300545002 3.24481027286706 0.00126599080650996 -313.021443401801 55.6440016763477 -5.62543012672748 3.31730840193888e-08 FAF1 other 2.48280606734558e-40 0.000304064488121718 1 3.24481027286706 -5.62543012672748 0.992942857709215 -0.477664322745212 4.26925730738042 -0.111884641368291 0.910966364517412 0.197212327241129 11.2584877013425 0.0175167689011742 0.986032368141992 MYADML2 other 1 1 1 -0.111884641368291 0.0175167689011742 0.514299054294566 -15.9302155644865 18.7340190985506 -0.850336250896582 0.395602755203174 -38.5179028132994 34.8420892020256 -1.10549923082856 0.269550189087315 FAM43A other 1 1 1 -0.850336250896582 -1.10549923082856 8.40210344535241e-12 13.8247361731996 22.7176053747014 0.608547245415004 0.543140758313085 -210.129697191961 37.330955885974 -5.62883248513094 3.24858512532983e-08 NSMCE3 other 6.33938704951839e-08 0.000297830284290238 1 0.608547245415004 -5.62883248513094 3.18772531632161e-32 681.80007763745 54.0921989311703 12.6044067556767 2.81728328340016e-31 158.762916129 154.871731983161 1.02512520584623 0.305872523840274 HSF1 essential 2.90879935114347e-28 1 2.77023465256738e-27 12.6044067556767 1.02512520584623 1.18167512241667e-16 49.5261854940924 51.0225419621351 0.970672639768651 0.332250727881157 -313.925171671921 65.8947643985865 -4.76403815291059 2.590132167362e-06 C6orf120 other 9.73936635895822e-13 0.0225004781378737 1 0.970672639768651 -4.76403815291059 0.000282084007921811 -73.6063949698072 174.597319016307 -0.421578036733385 0.673540808375042 -1457.18816296936 369.098801322536 -3.94796232810304 9.1873182370776e-05 PURA other 1 0.733699234413017 1 -0.421578036733385 -3.94796232810304 0.0214197524957538 -33.3572198967665 20.3705702496874 -1.63752018170814 0.102243308787002 -89.5840052900534 32.1700972637809 -2.78469799315505 0.00559106828270716 INPP5J other 1 1 1 -1.63752018170814 -2.78469799315505 0.177843729790305 -7.71009064217529 13.6167625740154 -0.566220538859092 0.571535188761305 -29.1048985175645 17.8921997123911 -1.62668084335142 0.104527371828559 NPY2R other 1 1 1 -0.566220538859092 -1.62668084335142 0.000160844539018896 94.1932429294403 41.3809124050109 2.27624857585388 0.0233152223471426 -234.156188145268 85.1520308055354 -2.74986029023804 0.00621002314522658 LRRC37B other 0.777059520339118 1 1 2.27624857585388 -2.74986029023804 3.59156063395609e-06 249.898581340543 56.9435825011112 4.38852931909695 1.4317467204826e-05 -102.145433719215 102.942700264436 -0.992255239631628 0.321620870263642 DDX51 essential 0.0208382347982132 1 0.123645646780878 4.38852931909695 -0.992255239631628 0.0232962413359255 16.884695998309 28.3235586288518 0.596136107738573 0.55139295410485 68.589054113774 32.8802314506328 2.08602710770924 0.0375555517705018 SIGIRR other 1 1 1 0.596136107738573 2.08602710770924 0.34534563717379 137.382459137666 214.918253891752 0.639231226989502 0.523007441652257 323.707370752049 249.494141026767 1.2974547996192 0.195159241746071 IFITM2 other 1 1 1 0.639231226989502 1.2974547996192 0.0186931121349712 -99.8302443133945 123.86030329875 -0.805990633436482 0.420689646549284 146.493212285137 144.563309508734 1.01334987959919 0.311457670691046 TNFAIP2 other 1 1 1 -0.805990633436482 1.01334987959919 0.000455168680805604 124.281059063138 90.9944082757113 1.36580984939832 0.172699567274611 -302.754528888412 143.199777767544 -2.11421088501878 0.035061778633247 ZNF445 other 1 1 1 1.36580984939832 -2.11421088501878 0.190192888185761 0.682488296086853 6.3221541321283 0.10795185973378 0.914084348508228 -20.3489665223921 12.6312440094017 -1.61100256690837 0.107914629533067 PGBD2 other 1 1 1 0.10795185973378 -1.61100256690837 1.85643360565733e-22 246.529151557963 53.4801205916606 4.60973439907325 5.29723927446112e-06 -273.884947806296 67.0433850562085 -4.08518972567798 5.23774189237082e-05 PRMT3 other 1.61992396429658e-18 0.425933170687595 0.0464726801548474 4.60973439907325 -4.08518972567798 0.01077062724638 1.60202237640455 2.33842349464276 0.685086503823934 0.493651723369743 4.94241168299867 1.70415785172988 2.90020767617369 0.00391684049618802 GP1BA other 1 1 1 0.685086503823934 2.90020767617369 1.22281732785684e-16 282.44812047907 71.0190514136517 3.97707537423931 8.17575723490848e-05 -254.063520297247 94.386415261089 -2.69173820824176 0.00738349558562605 PRPF39 other 1.00760147815403e-12 1 0.682757486687207 3.97707537423931 -2.69173820824176 0.705140893914662 -9.09818997625804 47.8342797263034 -0.190202299027303 0.849238729213977 26.8586831042674 65.6009366291631 0.409425299155368 0.682427720735225 PPIL6 other 1 1 1 -0.190202299027303 0.409425299155368 6.03544497309133e-12 161.698130757744 43.9041598463082 3.68297972956977 0.000259410570013217 -230.238937205089 73.5348006268041 -3.1310200781474 0.00185891767601676 ZNF74 other 4.57064247812206e-08 1 1 3.68297972956977 -3.1310200781474 4.891257615333e-18 14.7359103063284 2.67943660076345 5.49963014692332 6.48040517568703e-08 -17.6159893251604 5.50765282133885 -3.19845674674864 0.00148191383177238 CDNF other 4.09300437251066e-14 1 0.000595030803231583 5.49963014692332 -3.19845674674864 0.0443051619691444 -15.1464980111297 6.4469138013359 -2.3494184159855 0.0192480415132436 -22.451920405134 17.0012005644353 -1.32060793707128 0.187324892787661 NOTUM other 1 1 1 -2.3494184159855 -1.32060793707128 0.773818642983265 -6.68988807410297 9.34106144314604 -0.716180716166004 0.474330314724233 -4.3539174064069 16.5748176762564 -0.262682672681458 0.792940979963616 RBM11 other 1 1 1 -0.716180716166004 -0.262682672681458 4.13461414850265e-15 265.363886921018 31.5718859028101 8.40506923589888 6.11560452536487e-16 62.1789157214635 83.2584366677769 0.746818198972121 0.455575833710108 CCDC137 other 3.33291246510798e-11 1 5.93825199412929e-12 8.40506923589888 0.746818198972121 0.00296880440834581 296.534719227124 90.2695378135161 3.28499210707961 0.00110194509511061 81.2143764915656 191.812407921123 0.423405228951416 0.67220793369458 CDK10 other 1 1 1 3.28499210707961 0.423405228951416 0.0261502614115843 82.1305660377343 89.1254155396301 0.921516781048999 0.357289135972261 -213.834834905661 141.692507717178 -1.50914708442087 0.131983843876275 TCN2 other 1 1 1 0.921516781048999 -1.50914708442087 0.000242625271222224 465.886035366615 162.969799127287 2.8587262048641 0.00445692549682365 -203.459932873575 263.351370151875 -0.772579739213961 0.440188776808946 GAS2L1 other 1 1 1 2.8587262048641 -0.772579739213961 4.38862755756696e-05 144.696134180178 40.7409131775038 3.55161735206456 0.000424492469858619 -103.565381881545 75.0219916836629 -1.38046697451379 0.168148600521143 ATP6V0A2 other 0.227374793757544 1 1 3.55161735206456 -1.38046697451379 1.55113561261481e-11 -45.9150281976608 27.5441587379395 -1.66696062982011 0.0962370719852673 -208.181457730704 36.1813422437392 -5.75383456833273 1.64089716485675e-08 PRKN other 1.16474773151246e-07 0.000151060992996712 1 -1.66696062982011 -5.75383456833273 0.521514320403403 -112.749345098578 119.596120223199 -0.94275085920979 0.346330432035252 -176.245691438024 158.334519698852 -1.11312234232458 0.266269199441733 HS6ST3 other 1 1 1 -0.94275085920979 -1.11312234232458 5.08610330621059e-12 781.353064952251 111.624075872899 6.99986144424559 9.72851276735617e-12 -312.679952711528 295.831379850207 -1.05695329842917 0.291118173224005 HGS essential 3.8593351887526e-08 1 9.32088808240394e-08 6.99986144424559 -1.05695329842917 1.11230226596036e-06 97.2038892162634 22.2830012143834 4.3622440389008 1.60694957337142e-05 -87.8670504510219 48.4085199089621 -1.81511540977221 0.0701899711660137 RAD51D essential 0.00671385647733674 1 0.138454775241681 4.3622440389008 -1.81511540977221 1.13277010822243e-05 26.851869839729 69.7764385423667 0.384827176632484 0.700552678751631 -339.36193528289 101.996957741916 -3.32717703347173 0.000951448806458533 MAPK11 other 0.062608203881454 1 1 0.384827176632484 -3.32717703347173 0.707589553774047 15.8738703909535 23.212634061808 0.683846148122884 0.494433942484212 0.24265294502 42.7642542537787 0.00567420031646076 0.995475250876459 SP140L other 1 1 1 0.683846148122884 0.00567420031646076 0.000537947525352638 34.1828775896645 48.6161555067119 0.703117661883923 0.482360291126569 -261.126085987968 91.1318947705067 -2.86536438911481 0.00436813452383539 TARSL2 other 1 1 1 0.703117661883923 -2.86536438911481 1.71148853227202e-06 326.174431749093 63.8992572811298 5.10451053153972 4.96265468284642e-07 68.3678374714575 129.821444034318 0.52662977199194 0.598718521027909 SMYD3 other 0.0101884912326153 1 0.00448276597501517 5.10451053153972 0.52662977199194 0.00115536740519684 -253.728900280703 944.182840278892 -0.268728565545373 0.78826567694008 -4480.12925092622 1457.89820541221 -3.07300553241267 0.00225203634215012 METTL7A other 1 1 1 -0.268728565545373 -3.07300553241267 7.8360418558569e-19 -17.4978581913731 16.2598217076413 -1.0761408400407 0.28245666593315 -125.082460502785 20.8766215312272 -5.99150874655109 4.34271105091864e-09 IFNLR1 other 6.62537338912701e-15 4.03177293967286e-05 1 -1.0761408400407 -5.99150874655109 0.0187670071038626 176.276368334507 64.0686707270996 2.75136609412978 0.00618089942755525 88.618007315681 124.781724204034 0.710184186674481 0.477967861674694 SH3BGR other 1 1 1 2.75136609412978 0.710184186674481 0.0235505390527749 -7.19298837013315 21.4864638059419 -0.334768365567163 0.737960080356181 -106.158398411896 42.2400209804762 -2.5132184110648 0.0123214915586345 FAM174B other 1 1 1 -0.334768365567163 -2.5132184110648 0.0024901863965038 -4.66581338332898 47.9814986631525 -0.0972419268536125 0.922578855113274 -183.574936454428 69.7614359174455 -2.63146728619043 0.00880241113735254 GPRIN3 other 1 1 1 -0.0972419268536125 -2.63146728619043 0.0015716893428687 32.2680050472371 9.61447447580771 3.35619020347197 0.000859283141727636 11.5450854147803 16.7144058710207 0.690726640472283 0.490104058199066 PARPBP other 1 1 1 3.35619020347197 0.690726640472283 0.000155300882929748 41.6491328384345 14.2160166837348 2.92973297408177 0.00357186875035176 102.728517003424 24.7190163125527 4.15584971928097 3.90697641845952e-05 STAC3 other 0.752122176028768 0.320254857021127 1 2.92973297408177 4.15584971928097 4.25635722181222e-07 8.32854733723144 11.1145921419943 0.74933449926279 0.454057870375431 -32.6633455391119 14.2722192328394 -2.28859611853185 0.0225781987685688 ROR1 other 0.00264447474191193 1 1 0.74933449926279 -2.28859611853185 9.39245997437116e-05 48.1571289275351 21.8329381797912 2.20570994755575 0.0279253139668929 -71.8126254688953 37.9905734732844 -1.89027484724323 0.059384151378776 SDHAP1 other 0.467274883724965 1 1 2.20570994755575 -1.89027484724323 8.97719514381731e-19 609.893266879113 64.2641771257063 9.49040809603939 1.51866047639927e-19 117.07654334586 169.471501882983 0.690833220010635 0.490037977315953 FAAP100 other 7.58393445749686e-15 1 1.48449061568029e-15 9.49040809603939 0.690833220010635 0.0173271404194088 235.929443203287 85.9822860313952 2.74393080357437 0.00632017822003859 171.038044063876 99.7927179692674 1.71393311600702 0.0872485005307695 IRF7 other 1 1 1 2.74393080357437 1.71393311600702 0.359911263558464 -331.225497338832 357.118224044653 -0.927495364385033 0.354181368356154 -977.906694400137 691.969068681241 -1.41322313187183 0.158302001539387 SV2B other 1 1 1 -0.927495364385033 -1.41322313187183 0.0138111043728063 -28.0701773249739 31.5054678343634 -0.890962085456083 0.373439777640276 29.6509803747337 40.2735962499943 0.736238705644218 0.461980457088603 FAM131C other 1 1 1 -0.890962085456083 0.736238705644218 0.510574501556925 -1.21296342856322 2.97925323930859 -0.407136732305683 0.6841064588524 1.11930913435867 3.45777941006117 0.323707501728362 0.746313997848378 LMNTD2 other 1 1 1 -0.407136732305683 0.323707501728362 0.294193607980523 -48.0904742724045 31.4805181313122 -1.52762651719417 0.127333742129379 -40.2281008146556 39.9864284947921 -1.00604385860305 0.314955044009898 PRKG1 other 1 1 1 -1.52762651719417 -1.00604385860305 0.102132805643721 1.92142292058782 39.1073468867657 0.0491320192635734 0.960836482453497 61.3891971519765 46.294176316928 1.32606738116925 0.185508473451279 DLK1 other 1 1 1 0.0491320192635734 1.32606738116925 0.125623081456453 -19.2209078042611 10.2868725559011 -1.86848896006152 0.0623628152282027 -5.38187773199229 7.90090933279534 -0.681171939241604 0.496123491683599 TLCD2 other 1 1 1 -1.86848896006152 -0.681171939241604 7.06832823301249e-05 121.13062003181 495.847090435905 0.244290270868228 0.807120672073338 -3771.68398818986 984.88202885645 -3.82957945995743 0.000147135838009769 LSAMP other 0.357021259049461 1 1 0.244290270868228 -3.82957945995743 0.364636900911054 -131.489011829322 94.3248485238843 -1.39400183394969 0.164027072213174 -139.964515356841 111.292091280797 -1.25763217984377 0.209197984872236 AHNAK2 other 1 1 1 -1.39400183394969 -1.25763217984377 0.264990088013045 -69.3355064786888 51.4477219255346 -1.34768856391824 0.17845522980086 41.8546165756665 113.712802688773 0.368073036509536 0.712996587636792 OLFML2A other 1 1 1 -1.34768856391824 0.368073036509536 0.000642721520025319 30.3708806818154 104.244773372723 0.291341999212041 0.77092800450079 -462.975938091858 159.287778537041 -2.9065377290336 0.00384037510908484 SP1 other 1 1 1 0.291341999212041 -2.9065377290336 5.3251799956671e-08 137.348268741294 40.7283230817903 3.37230355557414 0.000811754796131909 -132.797733275708 67.5941739223615 -1.96463283105197 0.0500899529190442 MRPL40 essential 0.000348692786116282 1 1 3.37230355557414 -1.96463283105197 0.227917074929699 4.29283004183282 53.494738760025 0.0802477055003531 0.936077496539011 -102.898817119998 79.4515262181265 -1.29511441778349 0.195974060289998 DBX2 other 1 1 1 0.0802477055003531 -1.29511441778349 0.00266194528354902 65.6118899082559 19.2099076897201 3.41552343551173 0.000696507922946739 45.6803925009965 29.3832133935787 1.55464250587988 0.120760124507557 FAM212A other 1 1 1 3.41552343551173 1.55464250587988 0.000132995481571021 70.7021909046252 89.2253635913131 0.792400143399457 0.428562318079687 -401.990994864447 138.748921606475 -2.89725491348027 0.00395584152429918 PCGF3 other 0.648884954585011 1 1 0.792400143399457 -2.89725491348027 0.00397150098880795 2.29678766357563 25.6498041559642 0.0895440623877654 0.928691229056859 -134.952691742838 47.7233479355525 -2.82781274953893 0.0049056758256756 LMLN other 1 1 1 0.0895440623877654 -2.82781274953893 1.68284888463948e-06 2143.5676153332 409.395846360488 5.23592907546432 2.55844153584516e-07 1069.67450866518 1079.62059191471 0.990787427246179 0.322338919040935 P4HB other 0.0100230479569127 1 0.00232536751192967 5.23592907546432 0.990787427246179 3.18086628592887e-27 1072.9593930534 132.966360043003 8.06940486831702 6.8904438634723e-15 195.030650755121 154.35788809774 1.26349649608853 0.207084439194712 PSMD13 essential 2.8487838456779e-23 1 6.6789072368637e-11 8.06940486831702 1.26349649608853 0.929118484182364 -90.290133178244 441.666445538934 -0.204430592566455 0.838113079316282 -294.480503567976 767.976031181458 -0.383450122935407 0.701574240144457 NDUFA4L2 other 1 1 1 -0.204430592566455 -0.383450122935407 0.667590711371997 -57.0700024787615 67.8401204833275 -0.841242646271348 0.400673153453932 -80.2603488293483 102.572978821543 -0.782470683326706 0.434362764527771 SHC4 other 1 1 1 -0.841242646271348 -0.782470683326706 0.0556954744669826 357.27841977065 865.701339666333 0.41270401627004 0.680025883960215 -887.1652282197 987.168355768723 -0.898696988244575 0.369308981856864 ZFP36L1 other 1 1 1 0.41270401627004 -0.898696988244575 6.28120409466046e-17 330.331261969767 80.5290386086006 4.10201422589053 4.88793706261294e-05 -567.667332219551 132.188685989276 -4.2943715490568 2.16125432656534e-05 UBE2L3 essential 5.19895262915046e-13 0.179751522340439 0.412297491231402 4.10201422589053 -4.2943715490568 8.38089161406583e-06 239.179234202491 110.929133232709 2.15614444314404 0.0316161925538659 -616.579348300275 216.048317409238 -2.85389562711731 0.00452350360888624 BRWD1 other 0.046974897496839 1 1 2.15614444314404 -2.85389562711731 0.316985608358991 7.50726087881031 7.60122609736787 0.987638149772955 0.323877660173331 -4.13039562721228 12.2189369230948 -0.338032322550539 0.735501531600598 PMEL other 1 1 1 0.987638149772955 -0.338032322550539 0.000122192414086611 40.8239027407736 32.705006947249 1.24824626414603 0.212610780910678 -136.223377673436 52.414498790524 -2.59896366113995 0.00966754351391637 SYN3 other 0.599109406266654 1 1 1.24824626414603 -2.59896366113995 0.236686301392931 -4.98211949754925 4.98324559376915 -0.999774023535725 0.317971883996284 -10.1154995875954 6.39897287248481 -1.58080051114006 0.114645488587061 POU3F1 other 1 1 1 -0.999774023535725 -1.58080051114006 0.229048563901318 -6.84395759474066 5.7845207302151 -1.18315032721582 0.2373913606209 8.08438600718227 12.2910747944306 0.657744431825073 0.511047885969511 SNAI3 other 1 1 1 -1.18315032721582 0.657744431825073 0.349668123599798 -10.1134941014137 18.9490487920918 -0.533720410579897 0.593805730480109 -56.3596264380944 38.8484610915264 -1.4507557018877 0.147563662950856 MORN5 other 1 1 1 -0.533720410579897 -1.4507557018877 1.74373586631062e-05 83.1157816352297 19.8728229321999 4.18238425002807 3.48593905042843e-05 -26.5070348244688 35.6439548408138 -0.743661441129343 0.457480048950359 EP400NL other 0.0945627960300252 1 0.295886506600365 4.18238425002807 -0.743661441129343 0.00114121988018352 61.1876211102242 25.9293612798392 2.35978127073262 0.0187254882634867 -55.4206569106261 44.7401020681194 -1.23872441833604 0.216114047212612 C6orf201 other 1 1 1 2.35978127073262 -1.23872441833604 1.99691945845965e-16 200.999024164763 45.7033497318532 4.39790574091499 1.37519394145714e-05 -258.195019388303 72.1767328127144 -3.57726111069993 0.000386123398277281 DRG1 other 1.63987025928707e-12 1 0.118816756541897 4.39790574091499 -3.57726111069993 0.684810155822029 122.577543432893 260.108855311407 0.471254787870027 0.637693430294793 133.060529625586 189.557857718635 0.701952064804882 0.483081888583502 ANKFY1 other 1 1 1 0.471254787870027 0.701952064804882 5.14399893377263e-27 116.670554415549 10.5825049892467 11.0248522948114 4.18507146759675e-25 -24.9221384378016 33.6409936825996 -0.740826465262596 0.459196539444355 ZNF696 other 4.60079264636624e-23 1 4.10722913829945e-21 11.0248522948114 -0.740826465262596 4.05941936382882e-08 -223.728925505886 78.2450064643473 -2.85933806661297 0.00445135951211416 -1015.75924157101 170.815980612891 -5.9465117837713 5.66619896820495e-09 ADARB2 other 0.000267556330269958 5.25143320373235e-05 1 -2.85933806661297 -5.9465117837713 3.40670336309202e-18 -45.4958057674701 72.3133828370905 -0.629147800621694 0.529581040874541 -524.937513848888 87.4158129491568 -6.00506357075469 4.02691678757028e-09 NRG3 other 2.85788345129789e-14 3.74060300397403e-05 1 -0.629147800621694 -6.00506357075469 0.565582180552282 -465.186828349857 590.052770967674 -0.78838173675036 0.430900905428215 -754.966406747006 713.578036277017 -1.05800118328463 0.290639378328963 IFIT1 other 1 1 1 -0.78838173675036 -1.05800118328463 0.00366885714108304 -16.2910982540152 127.879296224658 -0.127394337746394 0.898687030931303 -439.664444411811 179.043167006555 -2.45563375448846 0.0144529203228522 KCNQ5 other 1 1 1 -0.127394337746394 -2.45563375448846 0.00926741857598877 152.367946223243 69.4796923463229 2.19298533251647 0.0288359929897443 -65.5735659686995 113.115198082503 -0.579706061433692 0.562412278705688 KCNIP4 other 1 1 1 2.19298533251647 -0.579706061433692 5.94024403678743e-20 349.550973316458 173.541785923265 2.01421790986419 0.0445989032734002 -2242.06683104261 318.036508546332 -7.04971527102519 7.03868598352722e-12 MORF4L1 other 5.07118633420542e-16 6.72476058866191e-08 1 2.01421790986419 -7.04971527102519 6.17205225055184e-14 37.3875424688565 6.6803569270198 5.5966384546964 3.87894699998755e-08 -18.3622778078684 11.3589629839361 -1.61654526331641 0.106703081754306 WDR53 other 4.87696494010353e-10 1 0.000357406176578853 5.5966384546964 -1.61654526331641 1.02362228553161e-43 478.037247322829 79.402168183147 6.0204558422158 3.68873333307494e-09 -143.187107216568 97.3581807302642 -1.47072496776902 0.142085166737819 DMWD other 9.64559279656439e-40 1 3.45671200642453e-05 6.0204558422158 -1.47072496776902 1.66904206396291e-12 263.149188325819 38.2454772290897 6.88053091217976 2.09274444768606e-11 -56.5928702703524 106.107587024324 -0.533353663554512 0.594061808322272 SLC52A2 other 1.27898693361478e-08 1 1.99940804531926e-07 6.88053091217976 -0.533353663554512 0.215244007278307 12.6624914314199 17.8668059959615 0.70871600857378 0.478878616024626 -40.8355277800033 35.3061920471739 -1.15661093457605 0.248063224453312 PIGP other 1 1 1 0.70871600857378 -1.15661093457605 0.0390957182893228 31.768595124076 66.6358517446869 0.476749291744575 0.633779507694515 -415.759911182986 175.725861273133 -2.36595745310797 0.0184200087704688 PCYT2 other 1 1 1 0.476749291744575 -2.36595745310797 0.00133349430017762 1146.62115555556 482.178162691478 2.37800307910091 0.0178358032918107 -737.939555555555 784.074292855456 -0.941160247542505 0.347142705477951 NAT8L other 1 1 1 2.37800307910091 -0.941160247542505 0.000115634269270954 41.6396288507694 10.9161182427104 3.81450877729137 0.000156053106279096 11.0331102669612 18.1152760084912 0.609050078055099 0.542807006659318 GNB1L other 0.569036239082362 1 1 3.81450877729137 0.609050078055099 0.281556246620186 -44.2363120567372 73.3469314218577 -0.603110603254966 0.546749426822222 198.671347517731 156.684227213274 1.26797285885902 0.205485880960259 EVI2B other 1 1 1 -0.603110603254966 1.26797285885902 1.84062360332532e-31 62.0632850565133 8.57096088185087 7.24111169238133 2.02809018463139e-12 5.72639645460555 11.2146571511822 0.510617166214655 0.609877580517186 ZNF829 other 1.67459935430538e-27 1 1.95021152154155e-08 7.24111169238133 0.510617166214655 3.03438234891546e-30 119.082877880917 15.3497028839932 7.75799237163722 6.19986998641456e-14 -109.525831461722 29.9448929641805 -3.65757966117075 0.000285805316710577 THNSL1 other 2.74824009341274e-26 1 5.99651425086016e-10 7.75799237163722 -3.65757966117075 0.00169020049795907 62.767885783992 170.740066288431 0.367622475195472 0.713333550200376 -650.086610793595 258.173872521254 -2.51801859128901 0.0121597139492966 TRIM69 other 1 1 1 0.367622475195472 -2.51801859128901 0.990628447503845 42.3864837255215 313.210212742831 0.135329187877804 0.892413920342053 34.4810723481148 363.599236333097 0.0948326313769436 0.924491235253963 IFITM1 other 1 1 1 0.135329187877804 0.0948326313769436 3.16026808688715e-08 1500.014611292 421.005334145986 3.56293493129913 0.000407873983246143 -905.513838470347 603.603096836614 -1.5001809023446 0.134303114401111 LAMP1 other 0.000209873403650176 1 1 3.56293493129913 -1.5001809023446 0.000178110118176617 25.3266783939328 71.8673935696266 0.352408472548761 0.724897548756484 -292.903318361144 105.869366425202 -2.76664844847338 0.00618658120922694 LINC00839 other 0.854216126775053 1 1 0.352408472548761 -2.76664844847338 0.501829777129664 82.1557679611087 70.3440745572696 1.16791312527998 0.243478605031829 86.8118210191485 109.685832586775 0.791458832666193 0.429105654575717 KLHDC8B other 1 1 1 1.16791312527998 0.791458832666193 4.48304214711497e-05 128.455973079083 37.3869660575508 3.43584908391193 0.000647177170254859 -90.1196218251712 73.8795397446765 -1.21981839811969 0.223191630893024 SETD4 other 0.232087091956142 1 1 3.43584908391193 -1.21981839811969 0.2131355116097 439.599117546032 318.879824815782 1.37857300254097 0.168731738416587 -351.244323496003 695.381123602151 -0.505110523674441 0.613735845896003 PTCH1 ts 1 1 1 1.37857300254097 -0.505110523674441 0.0547987389737104 -45.7163562723982 36.844117693308 -1.24080475078663 0.215342070691297 -55.9029430899636 28.2821968777083 -1.97661247220953 0.0487123001991508 RTN4RL1 other 1 1 1 -1.24080475078663 -1.97661247220953 5.06200132454751e-13 127.399951147455 40.473278445417 3.1477546677932 0.00175769917847902 -60.739195466621 52.2188539875679 -1.16316599902942 0.245395451737799 RNPC3 essential 3.92406342678923e-09 1 1 3.1477546677932 -1.16316599902942 0.0093316043224273 130.608152933556 201.871681019415 0.646986007517292 0.517984614503127 -552.872219050708 286.530479015332 -1.92954069302039 0.0543183050387421 IRS2 other 1 1 1 0.646986007517292 -1.92954069302039 1.74440021012473e-05 138.448529411764 61.6561496121461 2.24549424968454 0.0252366979441554 -378.132352941179 127.543987383484 -2.96472111856011 0.00319576390337078 BICD2 other 0.0945639353908617 1 1 2.24549424968454 -2.96472111856011 7.36597879620417e-05 181.162148337594 168.896198760589 1.07262418969175 0.284052763527577 -625.998976982102 238.85529492049 -2.62082939040763 0.00908831663473321 RASA3 other 0.371318991116652 1 1 1.07262418969175 -2.62082939040763 5.3999175511468e-10 242.549903191558 68.9319267013016 3.51868741813332 0.000479809651958716 -380.380696604414 126.17068982071 -3.01481031089662 0.00272329890108525 LRCH3 other 3.88848062858081e-06 1 1 3.51868741813332 -3.01481031089662 2.7655413577665e-39 117.262779970572 20.013287129093 5.85924637038306 9.17552751171199e-09 -63.9969533394927 26.6636875922737 -2.40015388411755 0.0168065728908583 ZNF566 other 2.5772079913026e-35 1 8.54608632440855e-05 5.85924637038306 -2.40015388411755 5.21320380159801e-29 108.458426522826 28.6046586595688 3.79163505545081 0.000170747164345572 -112.282094461255 37.5817156427419 -2.98767878317816 0.00296973599681541 ZNF529 other 4.70022454752077e-25 1 1 3.79163505545081 -2.98767878317816 4.99379525797682e-41 44.950516166299 8.40935710326539 5.34529757915079 1.45865855004264e-07 -22.441453898383 10.4835979587564 -2.14062519248355 0.0328583533894819 ZNF284 other 4.67369298194051e-37 1 0.00133102592691391 5.34529757915079 -2.14062519248355 0.626762886511901 -12.5038665494039 13.0004422023321 -0.961803172138321 0.336681582684424 -10.508805116543 15.0712145124193 -0.69727659359392 0.486001342639178 DLEU7 other 1 1 1 -0.961803172138321 -0.69727659359392 0.278523029540954 -0.145542088921817 3.26827943120073 -0.0445317152298531 0.964500866555061 -3.75395637090858 4.19678922630326 -0.894482941240117 0.371554807589114 MATN1-AS1 other 1 1 1 -0.0445317152298531 -0.894482941240117 0.00179545551742277 109.191560706649 45.7306108626249 2.38771270811713 0.0173766096256876 -218.4611679982 108.182501479088 -2.01937619311224 0.0440567152819988 AIDA other 1 1 1 2.38771270811713 -2.01937619311224 8.32324307529591e-05 44.552154490436 12.765475864629 3.4900504268613 0.000532097715330556 1.26279115370878 20.0159678770906 0.0630891876657196 0.949724396542178 C15orf41 other 0.416495083487807 1 1 3.4900504268613 0.0630891876657196 1.57276760201319e-07 128.748161176846 22.6202245212074 5.69172781888788 2.31199814942845e-08 109.744680327667 40.5147415062584 2.70875923793601 0.00701942020303208 KRT5 other 0.0010024820695232 1 0.000213836708840638 5.69172781888788 2.70875923793601 0.235975998186252 10.9111105434955 12.2063519265825 0.893887920741801 0.371875010879343 24.0036755056131 15.6865214528402 1.53021022396696 0.126689889423505 AGBL4 other 1 1 1 0.893887920741801 1.53021022396696 6.92718398246581e-08 48.1912398565326 11.4212297132547 4.21944405869056 2.97972694882384e-05 -1.01378850238416 14.2111329022681 -0.0713376272923574 0.943161684860955 CYP2R1 other 0.000450544046219576 1 0.253753546961838 4.21944405869056 -0.0713376272923574 0.132232699932936 300.652797407698 149.135563201918 2.01596983947174 0.044414604430196 286.028473921881 414.63978018915 0.689824005288159 0.490671024527957 PIP5K1C other 1 1 1 2.01596983947174 0.689824005288159 3.74686976982023e-06 106.669368472034 27.7788786281551 3.83994508561334 0.000141211477797051 -86.7666669712668 56.9509687474391 -1.52353276651099 0.128347125256942 ZBTB6 other 0.0217206040556479 1 1 3.83994508561334 -1.52353276651099 0.0184672549944428 23.5768666545301 53.1685786203316 0.443436090757452 0.657669290271568 -302.631680390622 122.711522476459 -2.46620426740022 0.0140373680634253 WWOX other 1 1 1 0.443436090757452 -2.46620426740022 9.41596661500222e-05 43.6075988970415 17.1562490631646 2.54179096704008 0.0113722068300203 -93.1179213996394 40.2697541055588 -2.31235386130122 0.0212210225384979 CIDECP other 0.46835017943021 1 1 2.54179096704008 -2.31235386130122 0.0180346130282311 -29.3620883005445 52.2487188762244 -0.561967622021554 0.574428852371895 -143.221031717009 63.9111105109699 -2.24094105973055 0.0255360483258967 POLR1D other 1 1 1 -0.561967622021554 -2.24094105973055 9.10953141564663e-09 367.49892559052 59.4432714077435 6.18234691475353 1.44785577510595e-09 241.076603153505 133.132594324411 1.8108007612776 0.0708567108645339 KIF18B essential 6.23274139458543e-05 1 1.36257706995221e-05 6.18234691475353 1.8108007612776 1.74383454869956e-05 143.493452119628 36.3151374699366 3.9513399126857 9.0568163327168e-05 -88.3558627532851 83.8142738345416 -1.05418634214632 0.292378779251609 ZNRF1 other 0.0945627960300252 1 0.754070527862001 3.9513399126857 -1.05418634214632 0.0167886456368256 4.94435918483875 8.97282868241937 0.551036842431453 0.58189066994543 21.9404035356959 10.7736603373961 2.03648554424342 0.0423053518234163 FFAR4 other 1 1 1 0.551036842431453 2.03648554424342 0.927310766253684 115.217320329836 403.387629282065 0.285624327485936 0.775302137391158 -107.329193001548 844.575642772346 -0.127080616070381 0.898935449584088 SAPCD2 other 1 1 1 0.285624327485936 -0.127080616070381 0.0362452341733092 184.192764304633 71.5709655369331 2.57356824688335 0.0103934500503263 84.1510684728449 144.015136137966 0.584321000760841 0.559305193616027 EDARADD other 1 1 1 2.57356824688335 0.584321000760841 0.144736405131023 -8.98225542843803 12.1433975714735 -0.739682232717025 0.459891817158455 -40.0355708615458 20.8695917277066 -1.91836866690565 0.0557185296671903 SLC51B other 1 1 1 -0.739682232717025 -1.91836866690565 0.478271832566815 -15.8268432020529 14.5318921917735 -1.0891109700781 0.276705186413637 -23.9082392717324 21.0954972300632 -1.13333376364605 0.257695499713403 SOWAHB other 1 1 1 -1.0891109700781 -1.13333376364605 6.52767858664989e-06 39.1832339203531 18.6106009197969 2.10542550932207 0.0358243644535629 -72.498566977485 29.5615472059533 -2.4524618577097 0.0145782752173251 BLOC1S4 other 0.0369466608004384 1 1 2.10542550932207 -2.4524618577097 5.95475212907872e-45 36.47772590743 7.98486534176362 4.56835830613683 6.39971585942203e-06 -29.6973787379822 10.0136281304677 -2.96569618434545 0.00318508479941837 ZNF749 other 5.6278362371923e-41 1 0.0559783146223645 4.56835830613683 -2.96569618434545 0.00177942837793934 -226.969721703121 106.581850310132 -2.12953444740061 0.0337722341459263 -506.970238526674 144.269984950202 -3.51403820206723 0.000487713001784587 KLHL32 other 1 1 1 -2.12953444740061 -3.51403820206723 3.37597239163183e-71 32.2873376035905 9.76497364429289 3.3064439065292 0.00102267001133299 -84.865349056425 12.2460192617562 -6.93003556849335 1.5117777315246e-11 ZNF17 other 3.29798742938513e-67 1.44072417814294e-07 1 3.3064439065292 -6.93003556849335 0.498557294347069 -28.7352338117679 104.600806313441 -0.274713310771826 0.783666328319766 -193.616816588407 177.53913477427 -1.09055852296779 0.276068138476165 GABRA5 other 1 1 1 -0.274713310771826 -1.09055852296779 5.88284514076715e-13 612.033704704033 158.223749909232 3.86815320111637 0.000126315844177034 -860.944672927786 264.664537670964 -3.2529657373219 0.00123043287403844 PPP1CC other 4.5527338544397e-09 1 1 3.86815320111637 -3.2529657373219 0.00184303361363377 -655.020404148938 441.789918202576 -1.48265131720047 0.138889501148154 -1804.4832420192 568.435925868636 -3.17447078887869 0.00160746837576198 THBS2 other 1 1 1 -1.48265131720047 -3.17447078887869 0.000492850930930484 4.20660114928375 143.770117641159 0.0292592175502224 0.976671179572625 -1059.38620284721 296.641138632459 -3.57127203506255 0.000394616525462589 RXRA other 1 1 1 0.0292592175502224 -3.57127203506255 1.64947118867463e-15 51.2873187665923 22.8449525071924 2.24501752631989 0.0252663858463958 -125.950203525967 30.1793797147912 -4.17338609064381 3.6225739683046e-05 ANKRD37 other 1.33722629265852e-11 0.297775580194638 1 2.24501752631989 -4.17338609064381 0.728461520775303 -4.95330995177553 6.31488019169919 -0.784387003618306 0.433237067349316 -2.6589215256466 13.5692278787755 -0.195952308370146 0.844738371709562 C9orf47 other 1 1 1 -0.784387003618306 -0.195952308370146 4.35259951185715e-06 -12.9796135478889 13.9452110901962 -0.930757767949022 0.352491592574446 33.4030078400674 17.9070097566164 1.86535933659864 0.0627994273120482 CYP4X1 other 0.0251014413848802 1 1 -0.930757767949022 1.86535933659864 0.0103429160662631 67.3906954565724 28.9701296409363 2.32621311301783 0.0204626909809204 -92.0608727501406 65.0754690902975 -1.41467858836943 0.157873249985177 KRT10 other 1 1 1 2.32621311301783 -1.41467858836943 2.56121741709657e-21 48.8830532593803 16.990767942077 2.8770361307992 0.00421043985531701 -62.5249241545582 21.8190781829676 -2.8656079615392 0.00436249755267564 CCDC30 other 2.21750203972221e-17 1 1 2.8770361307992 -2.8656079615392 0.802756458310373 -88.0461445690617 145.685672980475 -0.604356919714829 0.545920722107779 -132.735488623856 224.456182005634 -0.591364815340767 0.554582476013587 GLDN other 1 1 1 -0.604356919714829 -0.591364815340767 0.353751761890819 26.4816227635438 21.1878519282705 1.24984934070687 0.212025049469963 14.353467695912 27.4654797890612 0.522600289750943 0.601517878966466 TRDN other 1 1 1 1.24984934070687 0.522600289750943 5.05232431275894e-05 40.0391620599365 19.1858690237699 2.08690896463073 0.0374740051735182 -57.0640858766057 30.193197939773 -1.88996495139179 0.0594226677888437 ZNF501 other 0.25968946967581 1 1 2.08690896463073 -1.88996495139179 3.09639971998372e-09 50.7817864416649 41.6561221057492 1.21907138433935 0.223473219287468 -278.123240892455 65.5550988377955 -4.2425874695212 2.69810904133686e-05 ZNF197 other 2.16159664452064e-05 0.223538334074759 1 1.21907138433935 -4.2425874695212 0.00322770868713755 551.721791205168 468.283727651033 1.17817843889787 0.239366645637424 -709.738034667444 592.498217868392 -1.19787370368951 0.231615478282009 GNG2 other 1 1 1 1.17817843889787 -1.19787370368951 0.0128013373173205 513.724807562458 201.082587100117 2.55479509673644 0.0109644982094935 -123.270465901418 418.002197610167 -0.294903870377211 0.76820800725832 BTN3A2 other 1 1 1 2.55479509673644 -0.294903870377211 0.0129777699188513 77.4044007767771 28.3905170259088 2.72641744094125 0.00666189543696845 36.8873311627842 45.9168577920834 0.803350510825765 0.42221192221187 C5orf38 other 1 1 1 2.72641744094125 0.803350510825765 3.14517696721908e-06 21.3681440318063 5.8945502091908 3.62506777845222 0.000322902634054407 -18.1368256980212 12.778621707536 -1.41931000957053 0.156521539721032 ZNF396 other 0.0183238010110184 1 1 3.62506777845222 -1.41931000957053 6.03315611484502e-53 330.948422028458 67.3469276666663 4.91408344069513 1.26555092766607e-06 -431.614777444879 86.162512607608 -5.00931048065523 7.95704615681741e-07 TMEM222 other 5.78941660780528e-49 0.00704357725801477 0.011312759742407 4.91408344069513 -5.00931048065523 2.24682499132681e-11 56.2469549534371 19.6625811979565 2.86060890923532 0.0044305695003144 -102.736018216454 15.0933453528061 -6.80670956736266 3.29857716386663e-11 SMYD4 other 1.67972636351592e-07 3.13331844795691e-07 1 2.86060890923532 -6.80670956736266 0.00188782257326582 244.851344086021 104.680374075544 2.339037725537 0.0197832369178688 -494.326344086026 236.83876496732 -2.08718511158524 0.0374502380671116 GPATCH8 other 1 1 1 2.339037725537 -2.08718511158524 3.37101627828384e-13 109.789626326264 22.8739916593565 4.79975808163571 2.18465791441968e-06 32.1904314382774 28.5115058077233 1.12903301759522 0.259503299121229 CEACAM19 other 2.62332486776048e-09 1 0.0194041315958756 4.79975808163571 1.12903301759522 3.53690609934446e-16 208.897352305596 65.0764265810407 3.21003108622525 0.00142507046754947 -525.8965563376 106.814620719307 -4.92345104814424 1.20759315230705e-06 NF2 ts 2.89778716719292e-12 0.0106231969608451 1 3.21003108622525 -4.92345104814424 0.160711345078642 4.72487628933618 2.49515583348548 1.89361971942891 0.0589342406357795 4.63295745320059 3.21944187020126 1.4390560972952 0.150848854484065 HPDL other 1 1 1 1.89361971942891 1.4390560972952 3.24996191604458e-10 3.09995014600108 6.1297422717628 0.50572275449186 0.613307455000326 -29.4717256605656 7.63064392274136 -3.86228553696916 0.00012940897768402 KTN1-AS1 other 2.35589739294071e-06 1 1 0.50572275449186 -3.86228553696916 5.58375414325505e-12 65.4894363181517 23.2071931457657 2.82194558845651 0.0049910511573216 -56.3358583695802 29.5571032797138 -1.90600066036396 0.0573059265403201 KATNA1 other 4.23081051434435e-08 1 1 2.82194558845651 -1.90600066036396 0.00140910246649881 13.7732467259717 8.36480116399765 1.64657192154814 0.100366619228139 -32.1800123010458 16.3998762523654 -1.96221067804731 0.050373603539126 FSD2 other 1 1 1 1.64657192154814 -1.96221067804731 4.01915354959986e-06 66.4140441327475 14.1701397914249 4.68690112520543 3.71633250636088e-06 19.2234300812585 16.5114078076684 1.16425142575248 0.244960266752506 KIF24 other 0.0232387458237864 1 0.0327966343686347 4.68690112520543 1.16425142575248 3.18429497782312e-07 70.2541778695472 63.7338065038878 1.10230632255209 0.270933841038323 -321.516776673584 94.526617407355 -3.40133589344504 0.000732098486362641 CARMIL3 other 0.00199241336762392 1 1 1.10230632255209 -3.40133589344504 0.424483953841188 17.4848002168976 34.6633799672574 0.504417060119744 0.614223148145948 63.0932057553195 50.9109703701527 1.23928507542863 0.215906622365839 PRR5 other 1 1 1 0.504417060119744 1.23928507542863 0.000824589625254135 259.574543537198 107.695959604311 2.41025331396748 0.0163526170379304 -512.428015827466 256.832600539444 -1.995182911948 0.0466419894230419 ZFP91 other 1 1 1 2.41025331396748 -1.995182911948 1.20816393618473e-09 22.2052556818179 13.6813389406412 1.62303234925757 0.105303611051885 -85.8491802793559 20.9053175210535 -4.10657145929012 4.79416736918995e-05 BCDIN3D other 8.57675578297543e-06 0.390772582262673 1 1.62303234925757 -4.10657145929012 0.0031616537447324 151.143097643098 49.7082618915329 3.04060314908824 0.002503020274046 29.3607744107791 88.0632250691772 0.333405622922792 0.738988028672727 CFAP73 other 1 1 1 3.04060314908824 0.333405622922792 1.23075997631611e-11 116.645099977367 26.0702354744106 4.47426338330779 9.80725518467546e-06 -48.9668866830794 32.6972612403579 -1.49758373715533 0.134968354585663 CCDC73 other 9.26146882177872e-08 1 0.0852054330444604 4.47426338330779 -1.49758373715533 2.02103876215904e-07 1326.89680171746 562.670143009051 2.35821434317001 0.0188016739967293 -2513.72728418177 901.604872539533 -2.78805867264382 0.00553334714483602 BCR other 0.00127972174419911 1 1 2.35821434317001 -2.78805867264382 0.113135503628728 -97.8648689251141 105.659294795246 -0.926230570767706 0.354837396051774 -313.187035228726 155.165986623701 -2.01840005044564 0.0441600199785645 MPPED1 other 1 1 1 -0.926230570767706 -2.01840005044564 0.000356745173877333 32.3088011443874 9.70842771575746 3.32791282896899 0.000949350670885737 3.19471699035944 14.6936347087717 0.217421832901036 0.827981561313167 HYAL3 other 1 1 1 3.32791282896899 0.217421832901036 1.48960872061217e-16 -7.13458072434481 8.98837256767274 -0.793756675152161 0.42776887638979 -53.167057905037 11.1251314073072 -4.77900493562851 2.41185399723149e-06 VSIG10L other 1.22594797706382e-12 0.0209758942139223 1 -0.793756675152161 -4.77900493562851 1.89638236952882e-29 410.413148323849 39.6481389208644 10.3513849450289 1.3207945738473e-22 -92.2124525616688 85.9520320800037 -1.07283621259632 0.28393668557827 ZNF397 other 1.71262291792147e-25 1 1.29451076182774e-18 10.3513849450289 -1.07283621259632 6.52570559131474e-22 246.370515948318 32.6136187793449 7.55422198361965 2.4889045573636e-13 -192.346408240714 70.7021031469427 -2.72051890508764 0.00677803896593939 ZSCAN30 other 5.67540615276643e-18 1 2.40229067876735e-09 7.55422198361965 -2.72051890508764 0.252627633999537 -57.7268505388532 190.441553918056 -0.303121085452244 0.761942162883826 -530.176084798641 342.77358319042 -1.54672387487957 0.12265535307441 TPCN1 other 1 1 1 -0.303121085452244 -1.54672387487957 5.42472332895316e-17 -148.95420748238 134.691808726606 -1.10588913231333 0.269381558572035 -940.412619051557 174.552845635972 -5.38755249520696 1.16850766471598e-07 LILRB4 other 4.49167091637322e-13 0.00105890164576562 1 -1.10588913231333 -5.38755249520696 0.638227806228144 3.87154561765819 4.12421996536197 0.938734027324945 0.348388248770697 3.80355718713628 5.47792905139317 0.694342177755834 0.487838299290263 TNFRSF4 other 1 1 1 0.938734027324945 0.694342177755834 0.422988854395428 65.9762034021037 70.1137555738417 0.940988011013324 0.347230863493085 171.205320304019 162.803293564176 1.05160845678181 0.293560380048206 HEXIM1 other 1 1 1 0.940988011013324 1.05160845678181 0.681648759195261 7.48581636298689 16.7135849075058 0.447888134377749 0.654455378187407 -24.2128379183041 37.8287400310299 -0.640064614852172 0.522465259683675 KRT14 other 1 1 1 0.447888134377749 -0.640064614852172 6.09049573964098e-06 0.488165790748571 21.0602202670345 0.0231795197086658 0.981517631202741 -69.9083330227246 25.3646026951517 -2.75613751427249 0.00609298760859179 PDZD7 other 0.0346001062969004 1 1 0.0231795197086658 -2.75613751427249 9.50856586150843e-06 228.919278482326 63.3510422969842 3.61350453255642 0.000337132263889096 -133.425688517225 121.638916847731 -1.09689967631205 0.273287940573031 POFUT2 other 0.053000746112048 1 1 3.61350453255642 -1.09689967631205 0.000241790205951261 949.218874411875 931.684495883268 1.01882008191194 0.30885209241472 -8186.31129207386 2163.36014596635 -3.78407234104662 0.000175799764789781 MAPT other 1 1 1 1.01882008191194 -3.78407234104662 0.80918093035641 -0.201921295463876 77.1966505691049 -0.0026156743067903 0.997914187111015 -61.2006631068684 117.869607732713 -0.519223439223199 0.603867192484382 C1QL4 other 1 1 1 -0.0026156743067903 -0.519223439223199 0.0350275057829697 11.3733243085707 60.7930082348723 0.187082768870889 0.851682962179152 -346.630854344109 144.97761730632 -2.39092668775015 0.0172301543686243 RTN4RL2 other 1 1 1 0.187082768870889 -2.39092668775015 9.89969701160027e-10 53.042349726773 105.06844552241 0.504836151929742 0.613927817243288 -861.571571688788 171.035378555803 -5.03738804780491 6.91229430933438e-07 ZDHHC17 other 7.04957424196055e-06 0.00612982259351773 1 0.504836151929742 -5.03738804780491 5.28626497935123e-07 -73.5133559980593 77.7252413643739 -0.945810584922221 0.344767867733241 -526.759264573861 113.616262516877 -4.63630164295902 4.69106555071169e-06 PPARA other 0.00326849763673287 0.0403384726705698 1 -0.945810584922221 -4.63630164295902 0.160282919798827 -15.9037854546245 13.8161097207648 -1.15110445531003 0.250323045552318 -36.4905418054376 19.1503547577602 -1.90547602209044 0.0573787558419427 LINC01551 other 1 1 1 -1.15110445531003 -1.90547602209044 0.00178364846680858 130.446741497328 41.055522568308 3.17732507923366 0.00159159637328733 94.5920304820599 52.7223760464708 1.79415340459398 0.0734782284706464 FAM183A other 1 1 1 3.17732507923366 1.79415340459398 0.710007427862507 -3.21488686300428 7.0278605171753 -0.457448871551655 0.647576303133062 2.19155529949579 10.3219939571227 0.212318986873995 0.831957407042468 EFCAB6 other 1 1 1 -0.457448871551655 0.212318986873995 0.208180037716349 -75.308981915941 86.7501070543223 -0.868113994012515 0.385808406712736 -247.456424599661 140.184007564088 -1.76522578359397 0.0782241908544846 EMID1 other 1 1 1 -0.868113994012515 -1.76522578359397 0.125392795844583 -2.18173922483968 8.912519164517 -0.244794898565351 0.806730147627128 -14.4887369449569 11.3997393289994 -1.27097089914148 0.204415131072915 ESPN other 1 1 1 -0.244794898565351 -1.27097089914148 0.12694152434932 31.3835255123483 16.4592591858185 1.90673985736787 0.0572098206488983 0.967111712805602 36.3794753041598 0.0265839928893922 0.978803675788988 PTRH1 other 1 1 1 1.90673985736787 0.0265839928893922 0.388818108013346 29.0867691585708 23.6147967982238 1.23171795239664 0.218715331146037 -10.5688436043337 57.2031562934349 -0.184759798045387 0.853502958181994 TMEM216 other 1 1 1 1.23171795239664 -0.184759798045387 1.41917131660495e-05 305.927524588045 94.450635048922 3.23902030335302 0.00129070479826676 -108.59869726512 145.956390314011 -0.744048938395098 0.457245836233723 RPS19BP1 essential 0.0777422047236192 1 1 3.23902030335302 -0.744048938395098 2.01195379296039e-11 692.80666784509 252.954343443747 2.73886053274732 0.00641677405154632 -853.890154547878 307.836700775611 -2.77384130091199 0.00577659029519068 TEAD1 other 1.50634980478944e-07 1 1 2.73886053274732 -2.77384130091199 0.00088301685116013 118.729469254784 163.397509593444 0.726629613573672 0.467841027534959 -749.902198995519 277.96215452529 -2.69785719669722 0.00724824868063107 PLCD1 other 1 1 1 0.726629613573672 -2.69785719669722 0.194858066325929 -178.077480303201 174.639078533555 -1.01968861607905 0.308439048247982 -508.209196818643 280.697958433788 -1.81051974746913 0.0709003158863457 CCK other 1 1 1 -1.01968861607905 -1.81051974746913 2.60242863561034e-23 -54.4063429637484 42.7200460266898 -1.27355534518286 0.203496480378513 -330.039393219095 48.9723738473399 -6.73929743017801 5.02992331012098e-11 ENTPD5 other 2.28259015629383e-19 4.77188824431178e-07 1 -1.27355534518286 -6.73929743017801 0.970234519256498 8.36365376639131 37.284790853522 0.224318108669269 0.822614626831337 2.6044252305139 62.1648743137371 0.0418954475379416 0.966601180231607 MITF og 1 1 1 0.224318108669269 0.0418954475379416 0.244102891746408 -1.97157475838543 3.22548447639111 -0.611249185298007 0.541351721015494 -4.98446086791736 3.70099706445562 -1.3467886575183 0.178744745701037 HEATR4 other 1 1 1 -0.611249185298007 -1.3467886575183 1.06057569998593e-05 1306.12978142075 739.334897631616 1.76662806747633 0.077986975430078 -3164.19544626595 1203.5242690344 -2.62910813489835 0.00886204108125343 NAP1L1 other 0.0587877110502202 1 1 1.76662806747633 -2.62910813489835 4.45791816157817e-06 60.2412932138298 33.1200402107162 1.81887741773751 0.0696128542251826 -200.684726541063 62.1762542563805 -3.22767476010295 0.0013417450011627 CMC1 other 0.0256865244470134 1 1 1.81887741773751 -3.22767476010295 3.77597834187352e-11 597.254653850661 1183.07569918165 0.504832154243206 0.613930622994033 -5851.71418126835 1494.84688419931 -3.91459101471969 0.000104982728050494 SLIT1 other 2.81008308202228e-07 0.83335289526482 1 0.504832154243206 -3.91459101471969 5.87737624697774e-06 141.24404714114 67.1306372792618 2.10401767159707 0.0359489767792607 -376.558431533074 142.968305635509 -2.63385951074423 0.00874230971200218 AKR1C1 other 0.0334187613403154 1 1 2.10401767159707 -2.63385951074423 0.197521477225925 -75.2983592292397 49.8145549844983 -1.5115734598587 0.131370175171012 -50.5397545403853 63.5251410119385 -0.795586656484355 0.426707233377068 VSTM2B other 1 1 1 -1.5115734598587 -0.795586656484355 1.04109432069108e-14 48.1763936389856 9.53458387613544 5.05280505839049 6.4051825296171e-07 8.85759341273222 12.2433346753185 0.72346249184778 0.469781968427548 FOXD3 other 8.32563128256657e-11 1 0.00577235049569093 5.05280505839049 0.72346249184778 1.43904644416986e-81 80.6552537242098 27.9323485710635 2.88752138113314 0.00407518833853059 -369.169266310843 35.6911643695525 -10.343435772742 1.39590376917183e-22 SPATA21 other 1.41429484533014e-77 1.37189422434208e-18 1 2.88752138113314 -10.343435772742 8.21056163790137e-14 179.613436549291 113.137356319207 1.58756967983703 0.113105273050366 -423.09037957505 145.978514499886 -2.89830582962524 0.00394021603044733 RNF220 other 6.47320679532144e-10 1 1 1.58756967983703 -2.89830582962524 0.595415928216804 -244.24491179504 249.291199682723 -0.979757456764996 0.327747940621701 -280.151247863739 282.931260840084 -0.990174245970239 0.322636888387682 SHTN1 other 1 1 1 -0.979757456764996 -0.990174245970239 3.06442861143453e-41 43.1220599320529 9.57383449716944 4.50415765436537 8.56706731994215e-06 -59.4988635495055 13.1755804137149 -4.5158438323955 8.12789230400642e-06 ZNF546 other 2.86983739460844e-37 0.0691358519378786 0.0746191563566961 4.50415765436537 -4.5158438323955 9.89271661775723e-12 -429.19074507643 322.50490640206 -1.33080376935837 0.183945945129739 -2465.05134451177 431.893512718593 -5.70754427172403 2.1150975347606e-08 TSPYL4 other 7.45811905812718e-08 0.000194377463444499 1 -1.33080376935837 -5.70754427172403 0.063064055496254 1774.29991191397 866.06380743717 2.04869421476511 0.0410888276091258 -907.410578711151 1995.95895095003 -0.454623868030574 0.649605604025029 MT1X other 1 1 1 2.04869421476511 -0.454623868030574 0.748588908705731 -8.78703411946251 18.7974435980309 -0.467458996412841 0.640405065602403 -29.130534077719 39.2126335911875 -0.742886447807108 0.457950502328278 GCNT1 other 1 1 1 -0.467458996412841 -0.742886447807108 8.03558995333795e-05 -53.6871195237687 111.376608584276 -0.482032270565547 0.63002490114469 -1019.59334754406 241.676733172245 -4.21883122202496 2.98882621688949e-05 FNBP1 other 0.402904480260365 0.247086263350254 1 -0.482032270565547 -4.21883122202496 2.01416515988663e-13 713.738610957303 113.685715915641 6.27817316545664 8.27076056598331e-10 438.726372157291 141.704648574448 3.09606196106401 0.00208727465692775 BCAM other 1.57487573851536e-09 1 7.80594382217505e-06 6.27817316545664 3.09606196106401 0.00264474061030104 153.975079351463 72.1130495715178 2.13519023625202 0.0332997078007726 -71.6394905779084 112.159403141855 -0.638729242231267 0.523332935463652 DCC ts 1 1 1 2.13519023625202 -0.638729242231267 0.295676891386294 14.9182301085001 18.6634056800263 0.799330538287856 0.424533020353341 -37.6273836922567 39.3484151464564 -0.956261733851442 0.339468716076459 PCDHB13 other 1 1 1 0.799330538287856 -0.956261733851442 0.000327351380679741 374.927214700515 475.381615237704 0.788686820614721 0.430723697619189 -1439.53759750525 591.918109273341 -2.43198776140246 0.0154178512237944 LUZP2 other 1 1 1 0.788686820614721 -2.43198776140246 1.25294432301891e-13 163.284675270003 110.795033151316 1.47375446918275 0.141269317606518 -885.070831045971 170.700588586121 -5.18493133724282 3.31395682940536e-07 CHP1 other 9.84939532325165e-10 0.00296897392346427 1 1.47375446918275 -5.18493133724282 0.000311026874828694 -74.5200256797727 37.8082959251432 -1.97099667827704 0.0493592214075895 -160.590793914118 47.352202263944 -3.39141130161118 0.000759017944003159 FPR3 other 1 1 1 -1.97099667827704 -3.39141130161118 5.72395205821868e-05 814.529238541438 184.621742393398 4.41188143921755 1.29628487090351e-05 763.814457072843 241.853349158418 3.1581719241462 0.00169925807466218 C11orf96 other 0.292533635533537 1 0.112128641333154 4.41188143921755 3.1581719241462 1.59553532934099e-05 36.7282171337411 143.371827500543 0.256174576093774 0.797936862944302 -597.916938735601 178.235991884358 -3.35463635831498 0.000864163772657563 KCNJ11 other 0.0869407200957905 1 1 0.256174576093774 -3.35463635831498 0.943392041083554 96.9627481077354 923.046721909016 0.105046414018133 0.916387287347915 -244.282098038715 1309.53841122808 -0.186540613046721 0.852107596850166 COL4A1 other 1 1 1 0.105046414018133 -0.186540613046721 0.162757454462064 -1.11711768506985 16.1391924874776 -0.0692176938800762 0.944847928053077 19.958939025394 20.7242956358221 0.96306959600088 0.336043987170902 GJA4 other 1 1 1 -0.0692176938800762 0.96306959600088 4.20437730065775e-35 166.216711131509 15.378902203774 10.8080998844456 2.69169614081832e-24 -32.7288250125104 31.3839399797052 -1.0428526511864 0.297591786701131 HSPA14 essential 3.87391324482605e-31 1 2.64082308375685e-20 10.8080998844456 -1.0428526511864 0.00649144092829557 24.1136403000747 34.3606808760051 0.701780048745013 0.483191636301746 193.966119813373 63.9144914084954 3.03477529960587 0.00255153136619348 ATP13A5 other 1 1 1 0.701780048745013 3.03477529960587 4.4401406229594e-15 173.56096657346 20.5765228840731 8.43490260970195 4.91271071350139e-16 65.9785942979883 54.2624895028581 1.21591535704445 0.224675079193513 SIRT7 other 3.57475721554462e-11 1 4.77122464495255e-12 8.43490260970195 1.21591535704445 0.0215782707921532 -1.63935269620207 1.77651370431209 -0.922792034884339 0.356628314047845 5.11925025316602 3.09476755037501 1.65416308974343 0.0988173975333033 POTEG other 1 1 1 -0.922792034884339 1.65416308974343 0.626127356690352 0.384696748058724 21.9434893427759 0.0175312477450343 0.986020787486675 -48.5669179700686 51.9105588904645 -0.935588423783853 0.350000670027916 TLR5 other 1 1 1 0.0175312477450343 -0.935588423783853 0.635351312887136 0.800323075680296 3.7817387667979 0.211628334222025 0.832495663578273 -5.19739385617762 7.20851357672395 -0.721007708573905 0.47129030586701 NHLRC1 other 1 1 1 0.211628334222025 -0.721007708573905 6.55099485006935e-06 28.7104247950553 9.10717506222713 3.15250608436578 0.00172997367588866 -58.0290722312335 20.1070965154365 -2.88599958659788 0.00409456965350807 ZNF385C other 0.0370720798565425 1 1 3.15250608436578 -2.88599958659788 0.00794846393979247 95.3799724867277 35.2515992894379 2.70569206530455 0.00708224413371681 36.6477625542296 26.1639705689103 1.40069575669745 0.162013110528385 ZNF286A other 1 1 1 2.70569206530455 1.40069575669745 0.00660367963114135 678.925223704929 555.225341940822 1.22279221141403 0.222071777874811 -499.854834058925 737.804103093737 -0.677489908178809 0.498456158176132 ISG15 other 1 1 1 1.22279221141403 -0.677489908178809 0.000491106025712929 140.772116903634 48.7158849343636 2.8896553371308 0.00405130007325279 -133.526856240126 102.666777802853 -1.30058485420213 0.194095562871762 EXD3 other 1 1 1 2.8896553371308 -1.30058485420213 0.056403701988434 -2.07379016899043 22.0071524012649 -0.0942325536343007 0.924967914445221 -37.4981540148086 15.6523058462985 -2.39569520191022 0.0170115734523393 C17orf97 other 1 1 1 -0.0942325536343007 -2.39569520191022 9.59045270793228e-08 19.7773013641835 8.17682207777668 2.41870266664296 0.0159827062918296 -61.3435588095502 16.6381744897764 -3.68691642507078 0.00025548393220438 ZKSCAN4 other 0.000619735053986584 1 1 2.41870266664296 -3.68691642507078 0.000667206651288774 90.3907812059004 47.0529318001477 1.92104461396424 0.0553748489622138 -88.6261118290871 69.7864246017631 -1.269962064038 0.204772397671603 DHRS4L2 other 1 1 1 1.92104461396424 -1.269962064038 1.01041296873202e-09 103.463755796104 59.2308606030048 1.74678798759266 0.0813914364942799 -166.413883504855 77.776514018503 -2.13964183924809 0.0329486766003013 SAMD11 other 7.19211951143451e-06 1 1 1.74678798759266 -2.13964183924809 0.324261213907994 -5.58849734931182 64.7882628075181 -0.0862578668904104 0.93130102869089 -137.399244145468 105.270465742372 -1.30520220630281 0.192512375250816 ERC2 other 1 1 1 -0.0862578668904104 -1.30520220630281 0.016344734699513 80.3105988737075 97.8362017218556 0.820867914537681 0.412173198924098 -140.801681656048 118.573558362526 -1.18746273284269 0.235696145313238 B3GLCT other 1 1 1 0.820867914537681 -1.18746273284269 0.856954968073784 -173.098284930253 331.228297549028 -0.522595098942689 0.60152148893894 -23.9346444088717 655.927849793107 -0.0364897517561133 0.970908550635354 SPRY4 other 1 1 1 -0.522595098942689 -0.0364897517561133 0.117320589119718 -3.33513819867539 19.2657151566522 -0.173112608151679 0.862643067068948 29.6826515613143 14.3068276237675 2.07471931177834 0.0385972873569265 TRPV2 other 1 1 1 -0.173112608151679 2.07471931177834 3.63371757490701e-15 342.521021578578 45.4986358361863 7.5281602466455 3.00376916733308e-13 -54.8781202294006 95.8814473164115 -0.572353899167805 0.567378599724857 TMEM203 other 2.93131996767748e-11 1 2.89713536189275e-09 7.5281602466455 -0.572353899167805 0.885731128016182 -16.9829215106622 73.484191748433 -0.231109863313211 0.817337617901068 -43.511095705941 95.9715337700265 -0.453375016494008 0.650503762857557 SLC18A3 other 1 1 1 -0.231109863313211 -0.453375016494008 0.434649597775132 16.7438301392528 13.4012925431606 1.24941904561274 0.21218215551124 6.63965649681898 27.3808874116658 0.242492377876332 0.808512689152487 KBTBD12 other 1 1 1 1.24941904561274 0.242492377876332 0.399277745608682 146.793154178115 131.044387138494 1.12017887513928 0.263252797042899 288.482346018052 227.353713286985 1.26887017523178 0.205162805256392 THSD4 other 1 1 1 1.12017887513928 1.26887017523178 2.99260902067632e-06 -183.898034158697 132.925348815678 -1.3834685091833 0.16722595326891 245.463917607753 169.843545677953 1.44523547614336 0.149106813062573 GABRD other 0.017473844071729 1 1 -1.3834685091833 1.44523547614336 5.75510527129461e-16 10.6808300280322 2.78635708245502 3.83325959737417 0.000144977558756617 -3.50914735935612 3.59497375143872 -0.976126003131942 0.329540827174944 AMY1C other 4.69789243295779e-12 1 1 3.83325959737417 -0.976126003131942 2.20990418096124e-05 282.165746571209 63.5043554485058 4.44325030272941 1.12439449313068e-05 60.2164582075419 134.939467145837 0.446247932359645 0.655639194279681 FANCA ts 0.118517161224952 1 0.0974962464993614 4.44325030272941 0.446247932359645 3.03656997526242e-05 255.822994956073 68.2072529520208 3.75067142985552 0.000200051928273208 -153.454259500506 145.349608981712 -1.05575969949677 0.291659997458347 SECISBP2 other 0.160634551691382 1 1 3.75067142985552 -1.05575969949677 0.216080125992937 -100.549220028728 319.11890400845 -0.315083872392799 0.75284802725926 -1166.08415450223 680.042164268491 -1.71472331536467 0.0871033129098675 SEMA4D other 1 1 1 -0.315083872392799 -1.71472331536467 6.70117350473427e-08 205.075649959532 187.844156322651 1.09173292357992 0.275554803077188 -962.806597311338 279.982799140726 -3.43880624190562 0.000640599968994865 FAM69C other 0.000436380418628296 1 1 1.09173292357992 -3.43880624190562 0.562593198362901 -36.0874886074556 43.5563356924839 -0.828524439297195 0.40782480195519 -97.1627883426261 122.407344626398 -0.793766000227997 0.427761481798586 DNAH17 other 1 1 1 -0.828524439297195 -0.793766000227997 5.67829797213209e-10 265.798827792227 75.5985147544467 3.51592658474277 0.000483918756636006 -269.868620724906 114.358071692348 -2.35985634184984 0.0187197329785674 MCRS1 essential 4.0838319015574e-06 1 1 3.51592658474277 -2.35985634184984 0.901179007651633 -20.2787334296151 113.790213735577 -0.17821157693524 0.858639400880952 -59.0065958802975 147.243271356676 -0.400742222966253 0.688805773553404 TMEM72 other 1 1 1 -0.17821157693524 -0.400742222966253 3.61943532862063e-08 41.7489624095811 12.5178598072702 3.33515177932683 0.000925928240753507 -17.2662704059454 16.6366051141312 -1.03784818401919 0.299919951485014 FANCM other 0.000239389452634969 1 1 3.33515177932683 -1.03784818401919 7.60475107645541e-12 55.2652505583299 14.0853977877712 3.92358465064512 0.000101266605796062 -60.5842889764368 22.3911208702454 -2.70572828075546 0.00708148482282054 ZNF70 other 5.74234753783148e-08 1 0.841221694347887 3.92358465064512 -2.70572828075546 0.000931814974478007 127.060114660116 34.5892945751467 3.67339421693242 0.000269037023840469 51.2238226863231 72.8878441152269 0.702775933464906 0.482569592970474 CARD9 other 1 1 1 3.67339421693242 0.702775933464906 0.00785429306279686 16.3287621357096 7.53794336497409 2.16620918267747 0.0308339504830445 5.977143719436 9.68002012503777 0.617472240990065 0.537244161885185 ZFP69B other 1 1 1 2.16620918267747 0.617472240990065 1.02090590150859e-16 19.8481608467317 12.2315343371133 1.62270409416322 0.105372177430818 -52.6182995881801 15.7074009196611 -3.34990491789876 0.000878350526319269 ZFP69 other 8.42553640515041e-13 1 1 1.62270409416322 -3.34990491789876 0.0210403151413804 18.9809726698504 19.018233352073 0.998040791616507 0.318815701409417 -38.8194879746418 14.5464744440105 -2.66865267759953 0.00790097026501102 TMEM220 other 1 1 1 0.998040791616507 -2.66865267759953 7.91598048029944e-08 134.80816845006 43.9247240417843 3.06907263257525 0.00228063018775072 508.615583353067 87.6357372847941 5.80374626963192 1.24567002150653e-08 HIST1H1C other 0.000514063772390646 0.000114888146083547 1 3.06907263257525 5.80374626963192 6.30656619241064e-07 140.668365728786 28.6650408893253 4.90731432311231 1.30461974480373e-06 -53.6071088759004 21.4271576561574 -2.50183014173583 0.0127190695790403 PLSCR3 other 0.00388232214804799 1 0.0116567774198213 4.90731432311231 -2.50183014173583 0.0209765096924745 20.4124570706738 13.188871515922 1.54770308028486 0.122419318537583 -21.7272589707489 21.4588644816141 -1.01250739475822 0.311857063811169 CCDC157 other 1 1 1 1.54770308028486 -1.01250739475822 0.000175308215792409 84.0014580493828 23.1203969261255 3.63321868209205 0.000313317187271666 -24.9883144737815 51.1474823583362 -0.488554144243404 0.625403580555239 FAM122A other 0.84200536045094 1 1 3.63321868209205 -0.488554144243404 5.75640950592424e-08 -725.187254815853 143.099025492037 -5.06773021215444 5.96928275206732e-07 -557.928069559108 177.171612409638 -3.14908275637931 0.00175096092886135 SHISA7 other 0.000375812284315563 1 0.0053825022575391 -5.06773021215444 -3.14908275637931 0.318211580305982 -9.1542861750518 13.4866897779919 -0.678764494901495 0.497646392991069 -20.0913726290026 15.6689210013609 -1.2822435333778 0.200437010659337 DMBT1 other 1 1 1 -0.678764494901495 -1.2822435333778 0.0564075794467213 59.4273452651615 97.4207305744539 0.610007181374442 0.542174842247768 -91.1514749503712 125.192169192843 -0.728092464073883 0.466947824512932 LDLRAD2 other 1 1 1 0.610007181374442 -0.728092464073883 6.60253787029485e-31 1080.88918775103 84.8899983229613 12.7328214054007 9.1241872006034e-32 808.72722026626 230.305699698017 3.51153801806332 0.000492305831640427 CYHR1 other 5.99312362486664e-27 1 8.97272569307338e-28 12.7328214054007 3.51153801806332 0.000225150895599681 271.341516454842 1016.64049635233 0.266900165228915 0.78967164401376 -6038.76526823813 1872.94007887843 -3.22421701384826 0.00135766798150778 DNER other 1 1 1 0.266900165228915 -3.22421701384826 5.32834111456619e-24 81.3554365715034 18.3971144612357 4.42218461720866 1.23721300721864e-05 -52.5864464242616 24.4597514289865 -2.14991745018075 0.0321149923452447 KLHL17 other 4.69107151726407e-20 1 0.10711790216499 4.42218461720866 -2.14991745018075 0.00840334274119835 103.011161141981 33.2378118659844 3.09921608429955 0.002065950180606 67.9898447978549 68.7568569227455 0.9888445726111 0.323287633914615 ANKRD19P other 1 1 1 3.09921608429955 0.9888445726111 0.0103645552607888 3.19513191562581 6.29754584237161 0.507361438185664 0.612157180221312 -32.7952915690106 13.0901232508069 -2.50534627830865 0.0125959510573379 ZSCAN23 other 1 1 1 0.507361438185664 -2.50534627830865 5.96477923318395e-21 61.0104541756666 12.362646432597 4.93506422822206 1.14059568183356e-06 -21.4669323704033 17.4865342070797 -1.22762647624663 0.220246568378694 RINL other 5.14641152239111e-17 1 0.0102094719480922 4.93506422822206 -1.22762647624663 0.748330584139183 2.64945552428728 3.60302343490783 0.735342295755859 0.462527326104421 1.16566744157591 7.25429476508653 0.160686528370205 0.872414894934266 TPRG1 other 1 1 1 0.735342295755859 0.160686528370205 0.000668466170212519 -297.741198270533 199.895195473948 -1.48948651599451 0.13708063855162 -1043.14352816122 294.12570469149 -3.54659083351922 0.000432440417087919 RTP5 other 1 1 1 -1.48948651599451 -3.54659083351922 1.06309105744913e-06 183.1713803975 40.3412145340508 4.54055195197185 7.26934450202724e-06 -63.5806665819768 75.0026504567092 -0.847712263430944 0.397063344867819 RILPL1 other 0.0064306378065098 1 0.0634904548807059 4.54055195197185 -0.847712263430944 0.835066889449559 2.96846523680517 12.9172973422012 0.229805442900746 0.818350235302302 -13.0542640639332 29.8127439979462 -0.437875294700564 0.661692537267559 NRN1L other 1 1 1 0.229805442900746 -0.437875294700564 0.216416570762349 64.2517592817339 284.010673220324 0.226230086894974 0.82112824621333 -480.666599261233 435.033493650555 -1.10489561442212 0.269812780797625 ARL4C other 1 1 1 0.226230086894974 -1.10489561442212 3.61662437865694e-07 -4.86693279873884 9.24893174361796 -0.526215668322687 0.599004711932204 -40.3046114023145 11.8759384935451 -3.39380432327273 0.000751994491879191 RAB42 other 0.00225460363765474 1 1 -0.526215668322687 -3.39380432327273 0.000176929450230486 68.2598348712995 147.667983034079 0.46225209736593 0.644130602441351 -603.122333092945 215.856316831301 -2.79409165294109 0.00543349019351659 WNT7B other 0.848730572755641 1 1 0.46225209736593 -2.79409165294109 0.336447968046401 14.9801628702939 15.8952469187217 0.942430334482568 0.346504005185676 -4.44010385931788 23.0369609618385 -0.192738263813229 0.847255376448566 EYS other 1 1 1 0.942430334482568 -0.192738263813229 2.63911611004916e-12 218.000000000002 100.398005384664 2.17135787872238 0.0304415044823779 -573.934343434338 146.758581069949 -3.91073788837456 0.000106649156081489 MAPK12 other 2.01470123841153e-08 0.846047755194454 1 2.17135787872238 -3.91073788837456 5.66187448123916e-13 -186.075759145906 450.586566926143 -0.412963396612767 0.67983737592841 -2853.48729948007 598.756203589249 -4.76569141559589 2.57181521214349e-06 AGRN other 4.38342322337536e-09 0.0223465023783148 1 -0.412963396612767 -4.76569141559589 0.03077334245792 -54.9027932769446 53.4918036024601 -1.02637767993337 0.305281378994952 -166.829278323136 66.5947410807486 -2.5051419318659 0.0126031254705334 OTOG other 1 1 1 -1.02637767993337 -2.5051419318659 0.029108690232039 51.6935229067928 19.4180055085022 2.66214379659944 0.00805486484731806 35.5281657936313 40.9226694660682 0.868178109032944 0.385779981119283 FAM166A other 1 1 1 2.66214379659944 0.868178109032944 0.199254948235774 1.09522089432577 4.54070470730452 0.241200642835002 0.80951300072003 -11.7064697875415 8.25252894354744 -1.41853120026858 0.156750127869024 TMPPE other 1 1 1 0.241200642835002 -1.41853120026858 0.0458772444965402 -15.1714664872554 292.32871806941 -0.0518986522687555 0.958633216997074 -2692.58973292266 1103.4335856059 -2.44019193184531 0.0150767999247524 PRKAR1B other 1 1 1 -0.0518986522687555 -2.44019193184531 1.46810867626771e-16 27.9901747756262 11.8818217446555 2.35571407963736 0.0189280603209673 -45.8759594945677 14.4061305955749 -3.18447477552782 0.00155391521258851 NUTM2B other 1.20854706230358e-12 1 1 2.35571407963736 -3.18447477552782 0.000838278693838776 57.4087967489133 36.6837491395212 1.56496536192545 0.118316516012626 -69.1073651501609 45.6042482536869 -1.51537121642113 0.130403041338708 NCR3LG1 other 1 1 1 1.56496536192545 -1.51537121642113 5.53100514199928e-13 86.9688650895772 22.637345583648 3.84183140060374 0.000140252466200478 -11.0146229059898 30.0592662094375 -0.366430199235257 0.714221837219172 ZNF793 other 4.28321038196424e-09 1 1 3.84183140060374 -0.366430199235257 0.232287658965038 599.984597156394 390.315396662541 1.53717891296799 0.124983277764057 -63.1908830132219 822.574077350261 -0.0768209025219677 0.938801669585776 TUBB4B other 1 1 1 1.53717891296799 -0.0768209025219677 2.31542156686464e-12 44.1273226777276 22.81793139615 1.93388795467993 0.0537722774157269 -89.2932833633192 29.5261495172927 -3.02421022798866 0.00263973254401701 AGAP4 other 1.76967670355464e-08 1 1 1.93388795467993 -3.02421022798866 2.09891549635375e-08 328.656546466155 110.819873522125 2.96568238187477 0.00318676787137027 -143.191385287261 128.839040097896 -1.11139748618478 0.267012599256639 COMMD6 other 0.000141089099664899 1 1 2.96568238187477 -1.11139748618478 0.0893850831538458 -37.9757079610623 55.2430273963749 -0.687429884835642 0.492177375669039 -119.885761859456 70.6492000064683 -1.6969160563528 0.0904262221090423 PLA2G2A other 1 1 1 -0.687429884835642 -1.6969160563528 0.000548818735164876 -2.12057550750477 5.28475540570803 -0.401262753847482 0.68842281946356 -33.7244055149806 9.68495943965859 -3.48214215300518 0.000547501879206626 HYKK other 1 1 1 -0.401262753847482 -3.48214215300518 0.0277990495604625 -9.70841491896434 4.73320137444698 -2.05113075716088 0.0408499014446858 -19.4020883955739 7.36766051784868 -2.63341237677428 0.00875295183607744 C15orf62 other 1 1 1 -2.05113075716088 -2.63341237677428 2.59913637248808e-66 81.1774436534425 11.6468914410827 6.96988068138944 1.17881935093762e-11 -68.453424446217 15.3083305469538 -4.47164530686455 9.91188828228655e-06 ZNF383 other 2.53103899952889e-62 0.0840032531923785 1.12848376465258e-07 6.96988068138944 -4.47164530686455 1.07384271239256e-09 100.119104940327 49.1499140944248 2.03701485109377 0.042254827811577 -124.331073467281 65.3122354948928 -1.90364137018406 0.0576181106050647 HES4 other 7.63716937053592e-06 1 1 2.03701485109377 -1.90364137018406 0.00645323832859549 26.6892479904338 10.0039414004522 2.66787328334684 0.00791769807023992 -14.579103833123 19.7689117525666 -0.737476296904923 0.461229446690055 ZNF669 other 1 1 1 2.66787328334684 -0.737476296904923 3.7681932519423e-11 135.326643035064 20.4181655474702 6.62775716655068 1.00846483869247e-10 7.93777543590731 42.2377048414876 0.187931031425517 0.85101814819674 CENPP other 2.80466623742065e-07 1 9.5935260104815e-07 6.62775716655068 0.187931031425517 0.757250935726606 -29.0864806350685 130.506473298992 -0.22287385368564 0.823737821197157 160.189583834501 282.132188075607 0.567782020644778 0.570474576445819 PLSCR1 other 1 1 1 -0.22287385368564 0.567782020644778 3.94650734621837e-08 66.2259798331443 23.453088500036 2.8237636946214 0.00496334128373883 -94.6316937758829 36.5698398201745 -2.58769779253114 0.00998368387652319 C3orf62 other 0.000260390554703488 1 1 2.8237636946214 -2.58769779253114 3.05890030050359e-05 -3.91334868151593 9.6845096580341 -0.404083306197076 0.686349137429451 21.0807615711642 10.9913648442178 1.91793847897372 0.0557702250709202 ENO4 other 0.16175464789063 1 1 -0.404083306197076 1.91793847897372 0.000225645410115422 -289.840220183484 189.961662759233 -1.52578270780269 0.127792374315783 -1161.89556282408 290.562774356306 -3.99877639314972 7.48286811047288e-05 SLC38A3 other 1 0.600874309270972 1 -1.52578270780269 -3.99877639314972 3.70530530261401e-20 179.719670146253 81.4105480938888 2.2075722907428 0.0277917581195271 -427.44845748683 97.4456468048309 -4.38653209766205 1.44438994525602e-05 GTF2F2 essential 3.17100027797707e-16 0.121155428608075 1 2.2075722907428 -4.38653209766205 0.0125545466143125 149.149744735162 56.6490975350381 2.63287062327712 0.00877378229498118 53.0198714559207 66.0736889415757 0.802435467206961 0.422747480930983 FOCAD other 1 1 1 2.63287062327712 0.802435467206961 6.62400890309568e-21 80.262353987195 21.0038273135682 3.82132040932114 0.000152078980867857 -26.3859358646304 25.7165455518185 -1.02602955795377 0.30544785696217 PRR19 other 5.71320767892003e-17 1 1 3.82132040932114 -1.02602955795377 8.43452482133662e-09 -70.5830802765484 46.6829497213464 -1.51196701789119 0.131268368897025 -226.0935630673 52.9128630849692 -4.27294139620136 2.37169975250433e-05 JAKMIP3 other 5.78355366999052e-05 0.19685107945786 1 -1.51196701789119 -4.27294139620136 6.52613700026456e-09 96.2599483408018 17.8422315306858 5.39506216894731 1.12604544183553e-07 3.43059310607311 31.4402172114656 0.109114802960777 0.913161634214127 BLOC1S5 other 4.49716100688231e-05 1 0.00102943074292604 5.39506216894731 0.109114802960777 3.17258177027568e-05 55.9654188463893 29.2246359593897 1.91500824592506 0.0561484667795213 -88.2465181058495 44.1933153591128 -1.99682955190762 0.04646776102533 SLC24A5 other 0.167480591652853 1 1 1.91500824592506 -1.99682955190762 0.000627296034543765 153.359129201996 44.9674134321378 3.41045031272339 0.000708818744453477 290.644491398347 96.9462393420734 2.99799655325269 0.00287264084686055 IER5L other 1 1 1 3.41045031272339 2.99799655325269 0.787608999948903 -10.6505706760311 61.549164136949 -0.173041678556889 0.862698602730752 17.7460660498418 72.1597384760232 0.245927527242056 0.805853534469587 SERPINA5 other 1 1 1 -0.173041678556889 0.245927527242056 1.43300183101598e-59 120.964266157654 20.319549504316 5.95309783477041 5.42470877271097e-09 -154.024544819374 27.7523627528221 -5.54996150025863 4.97517390624715e-08 C19orf54 other 1.38614267114176e-55 0.000454531888074739 5.06884787722113e-05 5.95309783477041 -5.54996150025863 0.527761446000453 3.31890450915758 15.7007847017723 0.2113846264501 0.832685694894758 -22.2128779547007 27.7201825238191 -0.801325097178344 0.42337894522571 LCTL other 1 1 1 0.2113846264501 -0.801325097178344 0.878168773900067 -1.28239504239755 4.25484940866376 -0.301396105767299 0.763255499586314 -3.17127477458912 6.24772079416869 -0.507589067928424 0.611997049393883 C22orf34 other 1 1 1 -0.301396105767299 -0.507589067928424 0.00759111785876141 29.7018396846255 10.5912802763545 2.8043672634116 0.00526577419855156 10.5927914398351 14.8884666914811 0.711476316489735 0.477167859608626 COL25A1 other 1 1 1 2.8043672634116 0.711476316489735 0.0392783964407031 -7.71772459930546 3.8371195272814 -2.01133286165142 0.0449024120138747 -4.3218688905937 2.89570268059653 -1.49251127180756 0.136285086408052 FAM83G other 1 1 1 -2.01133286165142 -1.49251127180756 0.343315717685525 -20.0984641150282 18.9488026229258 -1.06067198624526 0.289423513412792 -53.8305931130265 39.9289271277939 -1.34816026838738 0.178303614008174 CFAP77 other 1 1 1 -1.06067198624526 -1.34816026838738 4.37309563402783e-41 285.530809047978 83.4999980961758 3.41953072524746 0.000686178086009992 -532.883964330617 106.738462919531 -4.99242681368151 8.62985015356727e-07 SRSF10 essential 4.09321751345005e-37 0.00762965052076883 1 3.41953072524746 -4.99242681368151 4.96655104235461e-16 16.5814700432369 9.0973731378574 1.82266570711885 0.0690356616166411 -61.4448144196753 13.3190710589682 -4.61329578824511 5.21138627342153e-06 DUSP28 other 4.0605777740819e-12 0.0447345397710504 1 1.82266570711885 -4.61329578824511 0.00212615095364783 58.2118200329726 108.091643180096 0.538541355468001 0.590477568922327 -399.64842916707 166.692774244546 -2.39751501514258 0.0169255257422553 C15orf52 other 1 1 1 0.538541355468001 -2.39751501514258 8.34010239296349e-06 590.653891535915 235.399405809422 2.50915625511012 0.0124636814479972 -1877.47567254183 532.593248175858 -3.52515860644539 0.000468025212203908 NBR1 other 0.0467879744245252 1 1 2.50915625511012 -3.52515860644539 3.84236764716469e-05 89.2608578755783 22.1437512640624 4.03097274762303 6.5626841724927e-05 -16.4596242140973 46.6654086815131 -0.35271574125564 0.724473184781724 NDOR1 essential 0.200610014858468 1 0.550543575230413 4.03097274762303 -0.35271574125564 0.361572579071867 -184.897354137185 130.579873054997 -1.41597131174504 0.157497872916562 -206.627521682052 169.941281134073 -1.21587597965109 0.22469006620423 NKAIN2 other 1 1 1 -1.41597131174504 -1.21587597965109 0.604341177591296 -2.64166119500987 4.43363193358468 -0.595823296697079 0.551601035309633 -9.4538739330269 9.68303345327112 -0.976333912161916 0.329437937535828 PAQR9 other 1 1 1 -0.595823296697079 -0.976333912161916 0.387288994025989 26.0185430463578 27.2090620280441 0.956245497163439 0.339476907862782 -13.2919079154832 46.1743550867436 -0.287863423116855 0.773587755081485 CFAP54 other 1 1 1 0.956245497163439 -0.287863423116855 1.35444089533275e-17 4.16449031226741 9.08697639474125 0.458292189982737 0.646972452766195 -64.0846052258972 11.845288401757 -5.41013465036374 1.04422415820446e-07 ASAH2 other 1.12838470990172e-13 0.000947111311491444 1 0.458292189982737 -5.41013465036374 0.00843439196410105 2.81391975188614 29.3996033362022 0.0957128475410798 0.923792511637111 -47.972227471556 33.3309837537862 -1.43926827440569 0.150790415870535 NANOS1 other 1 1 1 0.0957128475410798 -1.43926827440569 0.0491220180629891 -3.15331181681741 2.08161132893808 -1.51484178289231 0.130537070097558 -8.52965825928734 3.46847441569868 -2.45919595678181 0.0143122850291011 GOLGA8M other 1 1 1 -1.51484178289231 -2.45919595678181 8.42094118077334e-15 322.947131189215 219.265225956683 1.47286068632249 0.141510123253322 -1666.68063698632 322.040303987377 -5.17537903284195 3.47771969534582e-07 RTL6 other 6.74854226227175e-11 0.00311395021521265 1 1.47286068632249 -5.17537903284195 2.45021703264437e-07 -6.86558570713894 79.7310610978115 -0.086109298090445 0.93141888087504 -317.669700780304 102.869468391482 -3.0880853740915 0.00214257683749915 DPYD other 0.00154388175226922 1 1 -0.086109298090445 -3.0880853740915 3.99038266875364e-05 424.00651723117 108.299684145794 3.91512238078523 0.000104794301598242 -117.067295349064 234.02917537583 -0.500225218334697 0.617168307283588 PTAR1 other 0.208098456175502 1 0.869583114662211 3.91512238078523 -0.500225218334697 0.525853277232736 1.20344169628944 2.72426552312443 0.441749046146292 0.658888826031186 -0.977344986445982 3.44218026943758 -0.28393195880054 0.776596693984273 CC2D2B other 1 1 1 0.441749046146292 -0.28393195880054 0.0132181036896989 17.9137186660867 7.56900153928955 2.36672149861501 0.0183825242821986 -4.68431016636421 14.8396460554943 -0.315661852637642 0.752410225573158 SAXO2 other 1 1 1 2.36672149861501 -0.315661852637642 0.0710635073662888 7.08444914258874 5.14883600176698 1.37593217965332 0.169545757331595 -9.81200711433255 10.0280000607618 -0.978461014646936 0.328386480898434 LINC00319 other 1 1 1 1.37593217965332 -0.978461014646936 5.9051120372293e-07 10.7125901779791 7.05398517588396 1.51865788073997 0.129570093520472 -13.6354180270634 9.05688767390425 -1.50553021280714 0.132908605556666 RHCE other 0.00364168259335931 1 1 1.51865788073997 -1.50553021280714 0.450849417610034 -63.3059951875829 53.0410119009854 -1.19352917523066 0.233311206897035 -37.598663970508 77.9026565743077 -0.48263648024178 0.629596098147707 PARVB other 1 1 1 -1.19352917523066 -0.48263648024178 1.15090182115285e-28 173.491096132045 83.4384151962406 2.07927122925343 0.0381763518906253 -430.446250558961 96.8927666681589 -4.44250138953268 1.12874457875096e-05 UROS other 1.03615690958391e-24 0.0953337671213057 1 2.07927122925343 -4.44250138953268 0.900328136940713 1.52738503068651 27.7749724768465 0.054991414733525 0.956170667377748 -19.8600606471452 53.5880533187084 -0.37060612239504 0.711112152585834 OSTN other 1 1 1 0.054991414733525 -0.37060612239504 9.10965147850133e-06 109.093757225434 32.1136477129416 3.39711508952843 0.000743187236315457 -115.055710982658 64.0120566875127 -1.79740687827489 0.072959726820213 TMEM120B other 0.0508865131589084 1 1 3.39711508952843 -1.79740687827489 8.45331570727118e-08 142.001206874542 39.7682214753662 3.57072058056461 0.00039542459584941 -286.787098820588 86.3941406506602 -3.31952024362658 0.000977084095914892 RBM34 other 0.000547859390988245 1 1 3.57072058056461 -3.31952024362658 0.305847069590032 -1.18720379146889 20.7769787968153 -0.057140347645292 0.954459876610157 -62.8422299825394 43.7866512826613 -1.43519150566839 0.151957799170103 NOXA1 other 1 1 1 -0.057140347645292 -1.43519150566839 0.0439286414469131 91.4686012231803 36.9148294642308 2.47782808564266 0.0135945158527627 115.646884070602 51.3166666373726 2.25359306534495 0.0247155339042812 SPRED3 other 1 1 1 2.47782808564266 2.25359306534495 0.0447413293415301 16.4043289977974 9.92853232443307 1.65224108274574 0.0992036908672874 -10.2064912333643 17.2253748576359 -0.592526509159816 0.553804541698776 SKOR1 other 1 1 1 1.65224108274574 -0.592526509159816 4.6598054283744e-47 60.0247168240883 26.1679263427727 2.29382779658682 0.0222730033998719 -178.422188446182 32.8165688620264 -5.43695439935655 9.02210509636691e-08 ZNF548 other 4.42262133207015e-43 0.000819838690106861 1 2.29382779658682 -5.43695439935655 5.26636053378917e-48 75.9095336411914 33.3968647935209 2.27295388685462 0.023512560072864 -299.675117898715 42.8848283349696 -6.98790526938757 1.0444491585464e-11 MTF1 other 5.00778223158012e-44 9.96613387084972e-08 1 2.27295388685462 -6.98790526938757 4.98738266126573e-06 -93.292324363552 292.086463021858 -0.319399685279392 0.749576077265153 -1089.09627190157 218.741639371806 -4.97891610865353 9.21970170525673e-07 SHISA6 other 0.0285876774143752 0.00814284054608274 1 -0.319399685279392 -4.97891610865353 2.14219835124772e-20 121.317484390371 45.311365906155 2.67741839082127 0.00769791925449281 -162.039584171364 57.9140001351155 -2.79793458910315 0.00536988134166717 TMEM201 other 1.8358639870193e-16 1 1 2.67741839082127 -2.79793458910315 4.49467673844735e-08 114.038676720993 40.2912802131733 2.83035624873762 0.0048635358432621 -57.3423927802416 48.7915310477348 -1.17525299060899 0.240531988181034 NHLRC3 other 0.000295614889087682 1 1 2.83035624873762 -1.17525299060899 0.0313995976771543 23.6693592803374 40.0674819340726 0.590737379486017 0.555002484729829 -98.7416926748675 60.5917647710722 -1.62962232653123 0.10390356013446 ZDHHC11 other 1 1 1 0.590737379486017 -1.62962232653123 0.0139965739707577 1.04596774193554 3.69146874225691 0.28334731104781 0.777044794341863 -23.2209677419356 8.35192752751016 -2.78031240877615 0.00566524281419861 LINC00910 other 1 1 1 0.28334731104781 -2.78031240877615 1.89818351881066e-07 1319.89468566095 443.291317193801 2.97748824411084 0.00306782002321609 -1712.89058059426 742.327747021135 -2.30745864945487 0.0214957510552578 RPL14 essential 0.00120363816927784 1 1 2.97748824411084 -2.30745864945487 0.130687070881049 -13.1621064363328 13.9934496052964 -0.940590548262746 0.347434356459887 22.0592922819733 22.7804915269511 0.968341365939164 0.333409525524287 BEND4 other 1 1 1 -0.940590548262746 0.968341365939164 0.646527738247779 -14.2937999729978 21.6884707735875 -0.659050613674659 0.510211178745426 9.92478360660673 42.5220193303305 0.233403393416161 0.815557719800536 TMC3 other 1 1 1 -0.659050613674659 0.233403393416161 1.99898956822379e-05 307.764206444714 124.604584258101 2.46992683517345 0.013894172065817 -884.487632036369 272.915410687064 -3.24088562756377 0.00128248744361783 MSL1 other 0.107805507414309 1 1 2.46992683517345 -3.24088562756377 0.987200128470031 -47.147314498602 294.244698653851 -0.16023165315908 0.872775446798454 -47.375291058677 399.629727722248 -0.118547965209445 0.905690034205943 LRRK2 other 1 1 1 -0.16023165315908 -0.118547965209445 0.983598758853824 6.42634180658251 95.3921239122023 0.0673676352200443 0.946319845003326 16.0479737614838 110.756928120323 0.144893633597799 0.884861654504344 FAM196A other 1 1 1 0.0673676352200443 0.144893633597799 0.100400394065563 -41.9036096432274 20.293934698077 -2.06483416186404 0.0395447151260187 -44.1388694050809 23.7501670414051 -1.85846564060501 0.0637940629977166 HACD4 other 1 1 1 -2.06483416186404 -1.85846564060501 0.236222309138081 -23.6857033209962 79.0556144894309 -0.299608110998401 0.764618220432181 -97.0398154115903 58.6756008947465 -1.65383590337085 0.0988773125435621 USP32P1 other 1 1 1 -0.299608110998401 -1.65383590337085 0.0212442054960808 93.6525206068588 45.7724275663194 2.04604661771907 0.0413497954621128 -89.2888245131995 94.6843221620378 -0.943015934152175 0.346193792414528 FAM120AOS other 1 1 1 2.04604661771907 -0.943015934152175 0.386440331651877 2.63205885557257 2.42699685114329 1.08449207683672 0.278750136319796 -1.02016426781591 4.68256221574377 -0.217864540995506 0.827637287315728 UTS2B other 1 1 1 1.08449207683672 -0.217864540995506 1.76710170847307e-59 554.828956006911 79.5161637681226 6.97756191589989 1.13512969501885e-11 -489.499750314679 105.768418244182 -4.62803319214435 4.88831097717255e-06 NOC2L essential 1.70914077243515e-55 0.0419954796048893 1.08677317001105e-07 6.97756191589989 -4.62803319214435 0.216807593351993 0.565809200861321 3.55393434697999 0.159206430288203 0.873579790640146 -8.02678050351175 5.89585121082627 -1.36142860742017 0.174079800219549 MSANTD1 other 1 1 1 0.159206430288203 -1.36142860742017 1.61561761936456e-13 658.146524486568 97.2903943924961 6.76476366034066 4.36726238987524e-11 -229.921343643472 205.035612447647 -1.1213727259316 0.262753623067355 NELFB essential 1.26712889886762e-09 1 4.16593159370199e-07 6.76476366034066 -1.1213727259316 0.000464238751589459 16.3736098140758 4.46170774820913 3.66980778170599 0.000274300093971802 5.20228797011627 7.69126098786759 0.676389473497584 0.499169283155856 LRRC66 other 1 1 1 3.66980778170599 0.676389473497584 7.39931921058646e-10 -17.8853235816829 150.739341058837 -0.118650668472153 0.905606516963828 -1026.09611736328 214.504768936739 -4.78355853088699 2.35721330709203e-06 ZNF292 other 5.29717262285885e-06 0.0205077557717007 1 -0.118650668472153 -4.78355853088699 8.51947063967773e-10 35.7311630581434 15.1379366181455 2.36037208765384 0.0186950652735504 -35.2564522192963 19.2200563348686 -1.83435738194663 0.0672806722483152 ADAT2 other 6.08119814260196e-06 1 1 2.36037208765384 -1.83435738194663 6.68406765431164e-31 49.4455704841468 9.62785022698841 5.1356813118616 4.24629092030844e-07 -23.3294747401658 12.6493776341759 -1.84431799056536 0.0658150167082409 ZNF567 other 6.06645980305325e-27 1 0.00384119476651102 5.1356813118616 -1.84431799056536 8.89566116710533e-07 178.849763673195 43.3593083995354 4.12482971419146 4.44064240826396e-05 -30.3437480817623 72.5281212073344 -0.418372178634262 0.675880078268304 ALKBH2 other 0.00540856198960004 1 0.375234283498305 4.12482971419146 -0.418372178634262 0.00215414367889949 84.668721985953 24.6909589991071 3.42913865715037 0.000662822861949564 112.592624706957 59.3494143284544 1.89711433517846 0.0584703486702365 FAM111B other 1 1 1 3.42913865715037 1.89711433517846 0.200315404900961 -540.775488632883 1388.4253699121 -0.389488337185252 0.69710423977222 -4079.12297783906 2433.66628085171 -1.67612256862575 0.0944277830963763 APOD other 1 1 1 -0.389488337185252 -1.67612256862575 1.19361900606967e-10 1203.05676049713 550.998376391669 2.18341253267497 0.029536687155336 -3236.12476281092 851.556382490729 -3.80024720541173 0.000165055909806639 H1F0 other 8.76593798057566e-07 1 1 2.18341253267497 -3.80024720541173 4.37573339368868e-06 119.888250366574 66.1736143260202 1.81172286851246 0.0707232948962775 -257.437119540265 99.190457239311 -2.59538192186333 0.00977027178219238 ARID2 other 0.0252304787480089 1 1 1.81172286851246 -2.59538192186333 2.95152678351997e-08 991.862622318341 191.900081347602 5.16864096853462 3.59125065083626e-07 -536.580103921964 457.993700341193 -1.17158839416836 0.241999265847799 SF3B3 essential 0.00019651265324676 1 0.0032547504648529 5.16864096853462 -1.17158839416836 2.94082291013091e-49 59.5189557769585 13.3862250192304 4.44628382471193 1.10991072367757e-05 -65.8204922593084 16.6130773356659 -3.96196869065318 8.68224329123786e-05 BLOC1S3 other 2.80407464480982e-45 0.694318996000292 0.0962514579573188 4.44628382471193 -3.96196869065318 0.633668061556108 4.5510700389106 4.96697590714352 0.916265777002309 0.360032863173009 -1.04103289706399 11.2163350577421 -0.0928139977724197 0.92609386490387 SP6 other 1 1 1 0.916265777002309 -0.0928139977724197 0.0425344971613735 -27.3943183694461 18.5151578099526 -1.4795617002368 0.139712406003561 -53.7710588108083 22.4177282523508 -2.39859535299567 0.0168773060901705 PLAC9 other 1 1 1 -1.4795617002368 -2.39859535299567 0.435240210268077 -3.90038629951361 3.23087756384928 -1.20722194587488 0.227998207677617 -6.16088565736653 6.57418054974294 -0.937133626122791 0.349206259530808 NKAPL other 1 1 1 -1.20722194587488 -0.937133626122791 9.40447295029507e-10 22.0998612400884 7.95467594706715 2.77822269406669 0.00570116058900533 -9.21233173257117 10.6029642889841 -0.868844926898629 0.3854088751557 ZNF573 other 6.7025678716753e-06 1 1 2.77822269406669 -0.868844926898629 0.00985535115513316 0.336521491602624 2.00314382787836 0.167996669494797 0.866663441483174 -4.78012126000415 1.56477296533268 -3.05483374643291 0.00238932422273248 GRAPL other 1 1 1 0.167996669494797 -3.05483374643291 3.53239488817005e-05 -39.0608101464937 19.7657286666927 -1.97618872570659 0.0487618666855728 -127.041539671615 28.9026822140917 -4.39549308021229 1.38919151413605e-05 FAM47E other 0.185309435833401 0.116678195272287 1 -1.97618872570659 -4.39549308021229 4.51099219211042e-36 54.8063115732277 8.23600916934034 6.65447432686836 8.55394704327226e-11 -10.9614207576704 10.9362818714664 -1.00229866845967 0.316755298867152 ZNF527 other 4.16951008316766e-32 1 8.14164679578653e-07 6.65447432686836 -1.00229866845967 1.5802486871546e-24 -13.1559897444978 29.0573104113584 -0.452760064790965 0.650953649987287 -492.125275239618 53.0189495558899 -9.28206385380843 8.73605754140512e-19 ZNF33A other 1.39488551615137e-20 8.55784196756045e-15 1 -0.452760064790965 -9.28206385380843 0.0134557536885009 52.9318717205139 63.7539962237262 0.830251825074068 0.406848721429057 -132.606453094305 86.7001974700758 -1.52948271127149 0.126866678144378 PCDH18 other 1 1 1 0.830251825074068 -1.52948271127149 4.41739782436678e-23 15.9480941916716 3.55085727059541 4.49133631017431 9.09025057076635e-06 -11.5583895880102 5.30512203668162 -2.17872265861014 0.0298908514758679 ZNF600 other 3.86831527479799e-19 1 0.079094270216238 4.49133631017431 -2.17872265861014 1.5041625166525e-07 10.0645049340613 11.2849064378425 0.891855416745971 0.37296123672493 -80.4477170534451 19.5785980518813 -4.10896208401984 4.74664913683366e-05 C15orf61 other 0.000959505269372632 0.387089237108785 1 0.891855416745971 -4.10896208401984 4.43407041943419e-05 -448.499517972729 426.795596602247 -1.05085319891599 0.293905452523304 -2096.78066898499 571.55796941449 -3.66853544380275 0.000273972542835603 TSPYL1 other 0.229684847726691 1 1 -1.05085319891599 -3.66853544380275 1.84241300611336e-65 274.090884047864 54.373888876168 5.04085489768964 6.80071805683315e-07 -444.586909675784 69.5064126218869 -6.39634377470069 4.09854842808209e-10 PNRC2 other 1.79303633754952e-61 3.85796363535367e-06 0.00612472668198394 5.04085489768964 -6.39634377470069 0.0634102520279271 -3.086975366042 3.43894191846697 -0.897652661554148 0.369863902109085 1.80157291683084 4.41593648802621 0.40797074906213 0.683494498508559 GJB5 other 1 1 1 -0.897652661554148 0.40797074906213 5.14181022827869e-05 5.13905191114375 98.5942006581415 0.0521232676652305 0.958454236255119 634.409672591523 167.154431844283 3.79535059640253 0.00016819150448122 FHIT other 0.263877700915262 1 1 0.0521232676652305 3.79535059640253 1.02950517603467e-07 20.5604073336234 8.54671651913064 2.40564985250204 0.0165573151698302 -64.0837572178344 17.3908346552424 -3.68491555973229 0.000257438046730475 ZKSCAN3 other 0.000663104283883932 1 1 2.40564985250204 -3.68491555973229 9.96723855438636e-09 267.470851332389 82.9269264596971 3.22538001528829 0.00135251311439903 -233.128466859524 122.983761688984 -1.8956036443989 0.0586720168424083 RRP7A essential 6.80762393264589e-05 1 1 3.22538001528829 -1.8956036443989 0.000397634531262255 33.2218096889258 26.8910936727136 1.23542054827751 0.217336259830039 -78.2665646649803 39.3690726115131 -1.98802154770829 0.0474313938664482 LIN54 essential 1 1 1 1.23542054827751 -1.98802154770829 0.017524680718847 216.131274939773 161.534268300409 1.33799024327041 0.181595432284064 -29.4587129197386 187.552584106253 -0.157069085771964 0.875262943148904 FAM53B other 1 1 1 1.33799024327041 -0.157069085771964 9.63516450982845e-14 -161.078507129773 184.519327044733 -0.872962793164334 0.383161678816516 824.565761172626 235.773573215939 3.497278129714 0.00051804467988937 KAZN other 7.58865556794089e-10 1 1 -0.872962793164334 3.497278129714 1.51875289009652e-30 498.794751518455 133.388772818164 3.73940580590251 0.000208940210931648 -679.228097179361 176.906197336987 -3.83948164283644 0.000141469533688908 SLC35E2B other 1.37720512073952e-26 1 1 3.73940580590251 -3.83948164283644 0.0413503358829002 12.2063588651403 5.89773005300866 2.06967066234464 0.0390702945796269 -3.67813949950565 11.4193730558755 -0.322096447984345 0.747533653863821 ALG1L other 1 1 1 2.06967066234464 -0.322096447984345 6.76041073703112e-12 -187.78980500537 284.898456224876 -0.659146446399637 0.510148114660179 -1872.73104340768 367.841829475643 -5.09113127802038 5.29551650243824e-07 KIAA0408 other 5.11222259934293e-08 0.00471353923882028 1 -0.659146446399637 -5.09113127802038 9.82652448736158e-21 990.933761151975 324.258550222154 3.05599886409494 0.00238219034695684 -1618.10281063435 394.405209028113 -4.10264056760724 4.88300946904494e-05 HMGB1 essential 8.45572432137464e-17 0.39767229115902 1 3.05599886409494 -4.10264056760724 1.72716647757252e-05 4.23184038864335 4.23961760966144 0.998165584320537 0.318750187653975 -10.2355472214623 5.62277179437396 -1.82037393580579 0.0693843679320715 MMP23B other 0.0937851397321879 1 1 0.998165584320537 -1.82037393580579 7.33242735225072e-05 -36.6395905103358 48.8863055631099 -0.749485772923376 0.453967736010182 106.074740489578 62.7955346925499 1.68920833318683 0.0918928010995442 SH2D5 other 0.369700987100481 1 1 -0.749485772923376 1.68920833318683 3.39464764376617e-05 5.92366911923821 1.98819621942008 2.97941876228195 0.00304894268961709 -5.07920904566115 3.75412338135364 -1.35296806463236 0.176765365500847 SPATA41 other 0.178524519585663 1 1 2.97941876228195 -1.35296806463236 0.169588161829083 -6.89627546192797 6.82644770129529 -1.01022900396929 0.312943331879814 -15.2943445665623 8.30755111683356 -1.84101720849739 0.0662951654380011 RASSF10 other 1 1 1 -1.01022900396929 -1.84101720849739 0.194549425095096 -6.6043827059688 7.59340354655748 -0.869752630092067 0.38491416789993 -30.9124581530169 17.449979057167 -1.77148969931403 0.0771777684944581 OR2L13 other 1 1 1 -0.869752630092067 -1.77148969931403 2.01943366415275e-26 50.8957569665508 66.4778807196188 0.765604384730793 0.444325981205872 -472.627816767441 80.1897233876889 -5.89387014695702 7.55979629581025e-09 BLOC1S2 other 1.80012316822576e-22 6.99507951251323e-05 1 0.765604384730793 -5.89387014695702 0.364443755128014 207.553039015115 206.890477128926 1.00320247647636 0.316323464466721 -156.568231064415 399.16719733062 -0.392237218166837 0.695075939028317 IL1RAP other 1 1 1 1.00320247647636 -0.392237218166837 0.956059347775667 28.0588182135056 165.586169455364 0.169451460262623 0.865519781152735 -33.1352521979377 287.85099880208 -0.11511251423769 0.908408693369384 MYBPC1 other 1 1 1 0.169451460262623 -0.11511251423769 5.94856407846944e-08 28.0867846741906 11.1453857614907 2.52003701578777 0.0120928860660019 76.9107744812526 13.1347077157419 5.85553756853495 9.40933420944846e-09 PAX5 og 0.000388143806120131 8.68952014242566e-05 1 2.52003701578777 5.85553756853495 0.182725801635749 -184.024258395842 229.225903004269 -0.802807431376613 0.422521448194688 -532.995392683733 307.670438428543 -1.73235815376368 0.0839137693115747 SPOCK3 other 1 1 1 -0.802807431376613 -1.73235815376368 0.00375220749583077 31.631522629395 37.7627242717103 0.837638789029094 0.402691475523322 -223.381965177416 82.3491597485362 -2.71261984772572 0.00693892774785781 TDRD7 other 1 1 1 0.837638789029094 -2.71261984772572 0.309247492954881 154.525911296219 168.916498184673 0.914806504733946 0.360797705559178 -323.159167346464 389.860891577456 -0.828908911686158 0.407608462666392 KIAA0895L other 1 1 1 0.914806504733946 -0.828908911686158 0.000916237739188783 3850.55630252104 1134.27643231396 3.39472477151427 0.000749536216922599 7448.34695108811 2643.81063279855 2.81727702381007 0.00506234255950091 HLA-DRB1 other 1 1 1 3.39472477151427 2.81727702381007 0.565847644592924 -3830.09805349155 4680.34816789317 -0.818336139983288 0.413610253585129 -5840.44941911129 5487.20205233719 -1.06437659182308 0.28774455276781 SERPINA3 other 1 1 1 -0.818336139983288 -1.06437659182308 1.45035919730486e-13 55.1400532868299 66.1644155433989 0.83337928452889 0.405086113142321 -863.056497279138 140.141028017162 -6.15848555908585 1.66644392963632e-09 AKR1C3 other 1.13853196988431e-09 1.55579205270847e-05 1 0.83337928452889 -6.15848555908585 3.65068602399302e-28 164.941743266768 15.8462469786237 10.4088837873896 8.84854336183325e-23 -80.405782799443 42.8640287715771 -1.87583353930463 0.0613553968648857 ZNF250 other 3.28233180417212e-24 1 8.67422705760514e-19 10.4088837873896 -1.87583353930463 0.000502063807587665 22.3956075299485 7.0092582488234 3.19514658112475 0.00149862024807708 -15.0838562464347 15.4922777999141 -0.973637088183271 0.330774158320241 ZNF79 other 1 1 1 3.19514658112475 -0.973637088183271 2.82193108565005e-05 55.4941802567755 20.297214615668 2.73407860672361 0.00650909576115373 209.134241363185 46.8453769529135 4.46435176673667 1.02291969839178e-05 PLEKHG4 other 0.149872759958874 0.0866208400598164 1 2.73407860672361 4.46435176673667 0.0194225757786866 175.017608409986 62.7881252283496 2.78743166440274 0.00554387592833453 128.706513985358 88.2630698736067 1.45821479096146 0.145498008276537 FAT4 other 1 1 1 2.78743166440274 1.45821479096146 4.07981215571524e-31 0.979023931926514 69.6122781521703 0.014063954778012 0.988785361246257 -534.574528205616 80.8123372653203 -6.61501134969675 1.08563494687358e-10 ACADSB other 3.70691732468287e-27 1.02592502479553e-06 1 0.014063954778012 -6.61501134969675 1.81956728114635e-34 505.691358413843 121.096803573607 4.17592656032796 3.58241131370009e-05 -533.929684558552 155.500094553042 -3.43362932410581 0.000652224689137425 STK40 other 1.67291015828596e-30 1 0.303895951741178 4.17592656032796 -3.43362932410581 0.66009049169672 -6.16500195403818 6.90229476172058 -0.893181494975938 0.372253843474463 -2.53489790150249 8.12395611889642 -0.312027522601493 0.75516911212344 HRCT1 other 1 1 1 -0.893181494975938 -0.312027522601493 6.39990538006234e-16 30.5565160540419 79.5033290998152 0.384342597976982 0.700916319581261 -537.145188628992 98.9528518127078 -5.42829417029505 9.57170654763284e-08 MPHOSPH8 other 5.22104280905486e-12 0.000868855301340889 1 0.384342597976982 -5.42829417029505 1.48827744573009e-23 147.594776276172 14.2160665847081 10.3822513349041 1.03109880553007e-22 -75.4227715145996 56.6576087335349 -1.33120287284482 0.183817904057292 RNF216P1 other 1.30700525284017e-19 1 1.01068304918058e-18 10.3822513349041 -1.33120287284482 2.98357365867439e-69 83.9209780451234 17.0452040664865 4.92343639406024 1.21146112167604e-06 -120.493206816153 21.486505462341 -5.60785498727743 3.6564112993577e-08 ZNF766 other 2.9119678908662e-65 0.000334963839134159 0.0108340968111488 4.92343639406024 -5.60785498727743 1.85048413255325e-14 -474.678041687278 147.634749387758 -3.21521893494431 0.00139992771344466 -1436.24763733846 205.272600103263 -6.99678201872025 9.86648265480764e-12 RYR1 other 1.47483585364494e-10 9.41657104574841e-08 1 -3.21521893494431 -6.99678201872025 0.01186009151647 47.0588739639902 153.581805211364 0.306409173269102 0.759439057128387 -935.370036460625 354.879227564657 -2.63574186316726 0.00869404621725017 SRGAP3 other 1 1 1 0.306409173269102 -2.63574186316726 3.53152845839104e-06 5847.47105733827 1220.64095381331 4.79049227299037 2.28112060326664e-06 758.0427594499 2681.53142165004 0.282690239364582 0.777547841932099 TUBB essential 0.02050052270096 1 0.0202472264745947 4.79049227299037 0.282690239364582 3.82735427244854e-23 217.781931528381 43.8966520537663 4.96124240321639 1.00423542953466e-06 -104.226601118812 55.4645603782946 -1.87915671571067 0.060886849852959 LCOR other 3.35391054894666e-19 1 0.0090039748612078 4.96124240321639 -1.87915671571067 9.14875471129973e-48 927.905246622188 141.522606410778 6.55658675426656 1.55266540703994e-10 -744.305144308276 201.021467510035 -3.7026152158158 0.000240629239864492 SUPT5H essential 8.69497647761926e-44 1 1.47503213668794e-06 6.55658675426656 -3.7026152158158 1.48002167100328e-13 70.9687751813059 22.3551264972909 3.17460852614304 0.0016064749773159 -121.642788074133 33.9474207520539 -3.58327040403427 0.000377503684649946 XPNPEP3 other 1.16152100740337e-09 1 1 3.17460852614304 -3.58327040403427 1.10730660883208e-16 101.750088931801 38.7705057380895 2.62441995518874 0.00898371416489756 -75.895036219498 48.6539029429697 -1.5598961569118 0.119508294749692 ZNF471 other 9.13417221625585e-13 1 1 2.62441995518874 -1.5598961569118 5.0816121377378e-60 26.8870202392166 6.13300333946388 4.38398917316862 1.46435143888313e-05 -37.4333322457043 7.64411197709508 -4.89701516119466 1.37635994467613e-06 ZNF836 other 4.91950871054396e-56 0.0120844403142565 0.126358885661225 4.38398917316862 -4.89701516119466 0.245487612497366 -26.1239121699873 20.172875891704 -1.2950018782761 0.196004899714226 -67.1302276111466 44.9562851960271 -1.49323342261115 0.136099372632417 GRM7 other 1 1 1 -1.2950018782761 -1.49323342261115 3.63535394859437e-08 10.669075788578 12.918995584358 0.825844061863128 0.409344212657141 -129.349709284658 26.1088686023066 -4.95424414036963 1.04071161347076e-06 SUPT3H other 0.00024036960308106 0.0091686693146774 1 0.825844061863128 -4.95424414036963 3.30042362187545e-06 612.820989129146 146.080255155221 4.19509801976988 3.30460471500915e-05 -309.963576633612 302.179951469457 -1.02575824480183 0.305573003421759 IARS essential 0.0192018646320714 1 0.280792262634327 4.19509801976988 -1.02575824480183 0.319112781889038 5.99842796375079 7.76394728248091 0.772600295378879 0.440176620224559 -15.5879415572405 16.9308371515771 -0.920683449830982 0.357723679667342 MFSD14C other 1 1 1 0.772600295378879 -0.920683449830982 0.0113162819889215 30.4488216467853 16.9390103376808 1.79755611690324 0.0729360151108883 -21.8384760271349 26.6572700666211 -0.819231525679741 0.413099860848526 ZKSCAN7 other 1 1 1 1.79755611690324 -0.819231525679741 0.133493196440051 -98.7058534572544 80.4844626017161 -1.22639637846262 0.220709945188846 149.362358281098 164.437855070971 0.908321008058842 0.36420928412947 CPNE4 other 1 1 1 -1.22639637846262 0.908321008058842 3.39301442311888e-49 22.1115161977513 4.69041520554475 4.7141916501576 3.27036719962921e-06 -30.2389949036521 6.2218908749259 -4.86009727774471 1.63978715365728e-06 ZNF565 other 3.23422134811692e-45 0.0143579763174231 0.0289067756775225 4.7141916501576 -4.86009727774471 0.00238735228447689 81.6668845226909 89.4065959102178 0.913432434053309 0.361517676588749 -515.126679874187 188.397627221259 -2.73425248222053 0.00650571796092359 NTNG2 other 1 1 1 0.913432434053309 -2.73425248222053 6.63369255782759e-15 372.954664022871 48.935409223332 7.6213659994295 1.56875139485288e-13 -4.04095157424551 100.968516612653 -0.0400218970211067 0.968093904846498 WDR5 essential 5.32420164691242e-11 1 1.51478634686994e-09 7.6213659994295 -0.0400218970211067 2.23808011356151e-53 247.022163445235 35.4478064877371 6.96861633824057 1.18506542811092e-11 -754.925789533172 75.0810235584485 -10.0548148354089 1.55627115490263e-21 ASB13 other 2.14855690901905e-49 1.52872515546086e-17 1.13434462778778e-07 6.96861633824057 -10.0548148354089 1.07155873715433e-05 -323.0546662006 392.213460944454 -0.823670522227058 0.410576078204352 -1846.93482798219 508.374886559822 -3.63301743813589 0.000313395837456858 SLC35F1 other 0.0593643540383496 1 1 -0.823670522227058 -3.63301743813589 3.06682139585271e-30 135.481937881662 12.0109104033126 11.2799057966743 4.85291101482065e-26 -35.4109428846034 32.5847359145991 -1.08673407626846 0.2777603330879 ZNF34 other 2.77731345608422e-26 1 4.76458803435092e-22 11.2799057966743 -1.08673407626846 1.33507103193126e-15 29.8660729721088 9.95101283798914 3.00130986245858 0.00284219700534054 -23.83056450959 13.2639260810269 -1.79664485190987 0.0730824763983925 ZNF781 other 1.08394417082499e-11 1 1 3.00130986245858 -1.79664485190987 6.04388380793315e-05 107.914844883617 25.7843128704334 4.18529070081839 3.44625529897861e-05 -3.79838347983559 46.2506456897089 -0.0821260638244614 0.934584155262794 ZNF140 other 0.307815002338035 1 0.292552612330294 4.18529070081839 -0.0821260638244614 1.18871463528682e-05 3.91079844650545 6.13737421930209 0.637210361754699 0.524320749032716 -21.5240902243169 4.47269474019121 -4.81233159752743 2.05660606675377e-06 INCA1 other 0.0655694992824208 0.0179438879324266 1 0.637210361754699 -4.81233159752743 0.000649543333682102 19.416900236028 18.6766598737794 1.039634515339 0.299083282884444 -92.5570313158552 35.5450757735558 -2.60393399933935 0.00952917568601699 ZNF774 other 1 1 1 1.039634515339 -2.60393399933935 6.99396686044663e-16 349.107319202339 274.893215575094 1.2699743006461 0.20476804276255 -1352.59391112202 325.410849961476 -4.15657287174705 3.88700817638886e-05 EVL other 5.70078238795005e-12 0.318656930300359 1 1.2699743006461 -4.15657287174705 1.70896359076383e-36 38.3497795660883 10.8307222644439 3.54083307001478 0.00044212481444484 -70.1872525492563 15.0065773097286 -4.67709932122593 3.89448503778386e-06 ZNF765 other 1.581816699611e-32 0.033586038965848 1 3.54083307001478 -4.67709932122593 0.110352670984722 7.47200062957173 7.1194753977916 1.04951561907068 0.294520930931108 -19.0657736689944 14.0686346360047 -1.35519715752664 0.176054814087177 ZNF124 other 1 1 1 1.04951561907068 -1.35519715752664 1.25608688569902e-20 1109.14524576954 197.173247592961 5.62523191817192 3.31239934104876e-08 -856.001611603548 299.417818006903 -2.8588866798295 0.00445471356841192 XRCC6 essential 1.07973228694688e-16 1 0.000305469467231517 5.62523191817192 -2.8588866798295 6.72938311844324e-06 55.047111876872 55.8874386286192 0.984963942303184 0.325185552122491 -461.880533443704 115.312651210484 -4.00546278829907 7.27112028052821e-05 PPP1R26 other 0.0380412027685597 0.584452648148857 1 0.984963942303184 -4.00546278829907 0.145952603550981 19.1614068899038 49.7226129498806 0.385366048828088 0.700153739875655 -165.548060708264 103.78389066909 -1.59512290049047 0.111407671547966 TSC22D2 other 1 1 1 0.385366048828088 -1.59512290049047 0.0212973088062667 31.4328007591909 11.2791304181477 2.78681064886143 0.00555432196029517 25.1442150624621 26.9190645494373 0.934067193021674 0.350783879399267 NPIPB15 other 1 1 1 2.78681064886143 0.934067193021674 1.45579396445664e-36 61.458423686454 13.0512821417006 4.70899510248775 3.35069412455314e-06 -55.0071482239944 17.3302988560302 -3.17404498796939 0.00160977447832185 ZNF569 other 1.34777405229396e-32 1 0.0296100839786761 4.70899510248775 -3.17404498796939 3.79861756699726e-41 30.8546706803888 18.0944687883719 1.70519903298941 0.0888663494016419 -154.781210981348 23.2350609136321 -6.66153669907262 8.15028380903819e-11 YRDC essential 3.55626576622284e-37 7.71587368201645e-07 1 1.70519903298941 -6.66153669907262 0.0107890350552356 39.6961511299425 51.4976429882422 0.77083433001013 0.441221688250106 -255.10496918336 108.573465642123 -2.34960694746753 0.0192373990983374 PIK3R4 other 1 1 1 0.77083433001013 -2.34960694746753 3.15990888625092e-05 164.153233639928 44.2003776958393 3.71384232889439 0.000230634590548034 -108.131031670843 79.2844865959467 -1.36383593201411 0.173322887780702 ZNF605 other 0.166874788282911 1 1 3.71384232889439 -1.36383593201411 0.00334029601343436 693.740330037247 239.048607114578 2.90208898688429 0.00389471032345352 123.063201489663 380.686706387205 0.323266348482609 0.746648523044237 MYL6B other 1 1 1 2.90208898688429 0.323266348482609 6.87171086703173e-05 149.114573894444 54.0493525676309 2.75885957575273 0.00604334230347047 -64.9943057185439 80.1631465549454 -0.810775381353021 0.417934994526334 IPO4 other 0.347571135654465 1 1 2.75885957575273 -0.810775381353021 5.82683055442499e-05 2327.20971569637 610.18441787475 3.81394484605483 0.000156398270917271 -946.849964753412 1132.9205204399 -0.835760274150351 0.403745458549141 NCOR2 other 0.297544042509834 1 1 3.81394484605483 -0.835760274150351 7.54135741047858e-54 27.0359621147773 13.1042632397486 2.06314247662319 0.0396919528902781 -123.995568839245 16.487264679664 -7.52068770947711 3.14786752304087e-13 GDAP2 other 7.24799860721097e-50 3.03297035844988e-09 1 2.06314247662319 -7.52068770947711 4.39781136145826e-14 279.959711906371 58.0921801397353 4.81923231720611 1.99020513460961e-06 -248.812984674562 97.1721376076692 -2.56053834772206 0.0107852967681129 ANAPC7 other 3.48526550395567e-10 1 0.0177068550826217 4.81923231720611 -2.56053834772206 1.22447999467246e-10 22.5111097873897 275.617291036668 0.0816752450570847 0.934942272888045 -1301.77462990396 355.622616834869 -3.66055073068773 0.000282389849884016 SLC6A9 other 8.98768316089588e-07 1 1 0.0816752450570847 -3.66055073068773 0.0687964748973012 -519.399921112811 258.054926924237 -2.0127494843968 0.0447538764820914 -862.423116213859 409.900944997692 -2.10397933144242 0.0359510284487337 AFAP1 other 1 1 1 -2.0127494843968 -2.10397933144242 0.000282870477325995 1667.496059408 746.291481842407 2.23437637971073 0.025965582136662 -2135.71639442333 1297.53059087544 -1.64598538904765 0.100489039988179 NACA essential 1 1 1 2.23437637971073 -1.64598538904765 0.00423534284662974 -101.31719207874 173.179825348224 -0.585040387210315 0.558823202608907 -1257.45051840364 378.624689174738 -3.32110016688141 0.000972058714790401 MYO18A other 1 1 1 -0.585040387210315 -3.32110016688141 0.000195126869809508 69.2810431293888 16.5987954207493 4.17385969121494 3.61382223532875e-05 -2.1314124190755 12.9393392115177 -0.164723436354328 0.869237661732324 BORCS6 other 0.930560042121543 1 0.306488263778231 4.17385969121494 -0.164723436354328 0.000347534733762415 191.280328352064 186.430189887342 1.02601584253952 0.305451706239322 -1010.03445638936 361.235905043817 -2.79605222594594 0.00540122263929459 MAN2A2 other 1 1 1 1.02601584253952 -2.79605222594594 0.0471886542706001 -107.992063643972 161.392090306967 -0.669128601275141 0.503766784444731 196.864103361652 207.638606826489 0.94810934426159 0.34359778558634 LAMA2 other 1 1 1 -0.669128601275141 0.94810934426159 0.967898806987852 -37.0553666828458 335.685342013563 -0.11038720505511 0.912152976402486 -120.281381076418 490.69405603367 -0.245125001204753 0.806474711875771 PLXNB2 other 1 1 1 -0.11038720505511 -0.245125001204753 0.241212084861809 -158.0837308725 107.328262525862 -1.47289937572975 0.141496399869513 -231.50647271969 137.170246927508 -1.68773096137996 0.0921747737814428 AJAP1 other 1 1 1 -1.47289937572975 -1.68773096137996 5.49864128686191e-05 -132.620884955745 179.91404700269 -0.737134688286803 0.461436020356231 -900.619115044239 249.981176687899 -3.60274772275618 0.000351062732919019 MYO6 other 0.28153043388733 1 1 -0.737134688286803 -3.60274772275618 2.86967212342798e-10 343.091621620226 87.6094805183694 3.91614719765732 0.000104365180211364 -243.569476293296 133.789013381363 -1.82054916272539 0.0693592166041881 MKL1 other 2.08223409275934e-06 1 0.866126630574107 3.91614719765732 -1.82054916272539 3.35459654293585e-15 812.585559840249 175.305762492425 4.63524728615446 4.71099775419475e-06 -262.28749483542 234.766727760334 -1.11722601127354 0.26451015879935 HDAC2 other 2.70749486980353e-11 1 0.0414190922548803 4.63524728615446 -1.11722601127354 0.00158905865133902 22.0823799836194 7.27874450352668 3.03381716076449 0.00255880533105469 -11.1041718407354 15.8727556194545 -0.699574296168558 0.484565405762903 ZNF782 other 1 1 1 3.03381716076449 -0.699574296168558 0.351855473247069 10.6148980503053 7.33970146109442 1.44623021884087 0.148829464480067 10.474116819332 10.3429367937762 1.01268305396923 0.31177193733134 ADH1B other 1 1 1 1.44623021884087 1.01268305396923 2.25375588258876e-07 1072.47676088196 566.369328798059 1.89359964664392 0.0589369140231401 -2550.5959855235 904.798541331149 -2.81896562495673 0.00503626757053988 TCF4 other 0.00142369759103132 1 1 1.89359964664392 -2.81896562495673 0.502818298112621 105.517529649985 91.3368223869829 1.15525728717516 0.248617802843525 54.5311252531097 201.782632609352 0.270246871834014 0.787098207510753 HRH1 other 1 1 1 1.15525728717516 0.270246871834014 3.38058212592715e-08 955.383947583948 164.169630783649 5.81949257620615 1.14313579096622e-08 361.427323914829 345.944333470472 1.04475572786244 0.296713444384749 RABL6 other 0.000224064983306452 1 0.0001062430404124 5.81949257620615 1.04475572786244 6.17208894404424e-07 37.1224323537973 17.4357678006702 2.12909650886556 0.0338035146519421 -73.2679203099397 27.4390275355956 -2.67020834520801 0.0078624351287424 ZNF502 other 0.00380077237174244 1 1 2.12909650886556 -2.67020834520801 3.89271080725699e-13 -88.4637019600865 154.740932651502 -0.571689083452269 0.567827908563381 -942.128308071358 183.240022180633 -5.14149854851377 4.12795343477164e-07 TECPR2 other 3.02502556831941e-09 0.00368956477999889 1 -0.571689083452269 -5.14149854851377 0.623141161150715 -8.78696856264647 9.03287964917354 -0.972776003215146 0.331204009750922 -5.9934847885409 11.7795495954905 -0.508804240769559 0.611146816708207 FAM180B other 1 1 1 -0.972776003215146 -0.508804240769559 0.0784092896705017 7.579805468075 6.40973749973269 1.18254538011753 0.237633845038365 -15.1154216561537 12.5978399484831 -1.19984233153983 0.230852151953415 LINC00173 other 1 1 1 1.18254538011753 -1.19984233153983 1.80573652486299e-05 99.9892108134323 39.4486140034661 2.53466980626105 0.0116049029642537 -199.213722875501 79.8102520412852 -2.4960918902054 0.0129262257223037 ZFP62 other 0.0977899897100636 1 1 2.53466980626105 -2.4960918902054 0.0282271093446578 72.3987729360317 27.2020799639687 2.66151606906272 0.00806562888396172 -7.82286627267386 18.1552267663159 -0.430887830450454 0.666762385504575 TRPV1 other 1 1 1 2.66151606906272 -0.430887830450454 5.97028038614268e-07 -82.7598438351329 48.0946630583626 -1.72076980214425 0.0860020644652729 -280.770354185354 61.8112699118228 -4.54238126131187 7.20936500592926e-06 ZNF33B other 0.00367948380197973 0.0614670460405528 1 -1.72076980214425 -4.54238126131187 3.76524930068389e-06 174.919716312058 263.613025926718 0.663547317880579 0.507331583144424 -2635.83574468086 563.131987255461 -4.68067132454532 3.82547155391316e-06 NF1 ts 0.0218158544481625 0.0330099940387166 1 0.663547317880579 -4.68067132454532 9.82936012797724e-30 55.2321225664724 14.3376804802208 3.8522355580923 0.000134569946266142 -36.5896987831499 17.8882207938505 -2.04546328026812 0.0414074827433364 ZNF418 other 8.88770742771702e-26 1 1 3.8522355580923 -2.04546328026812 3.4727778750325e-05 -120.646551724143 168.060628310167 -0.717875167653674 0.473217844996953 -1598.25131845843 361.13142819881 -4.42567772744098 1.21565140097874e-05 DAPK1 other 0.182355566217957 0.102528039158547 1 -0.717875167653674 -4.42567772744098 0.0600251290698305 492.945938375356 271.69263272105 1.81435150978668 0.0703076383534335 1341.09561157796 633.270559783718 2.1177292878355 0.0347608067431041 HLA-DQA1 other 1 1 1 1.81435150978668 2.1177292878355 0.781068577737136 37.1193565127145 62.6805386750907 0.592199066844743 0.554022864403036 -15.5182494378138 130.597697269055 -0.118824832001772 0.905468611659886 COL27A1 other 1 1 1 0.592199066844743 -0.118824832001772 7.49075062613723e-05 -116.040311678915 176.282946726483 -0.658261697082706 0.510716614738551 -1433.69110087202 343.330688017233 -4.17583149689217 3.58535536654291e-05 GM2A other 0.377084386519748 0.294859625344489 1 -0.658261697082706 -4.17583149689217 0.00194202499410358 1.94309369197189 185.479853444505 0.0104760363774671 0.991646265940735 -1181.93921169751 371.919112215325 -3.17794695910444 0.00158850931188427 CD47 other 1 1 1 0.0104760363774671 -3.17794695910444 0.00424338972141539 160.033764367809 136.48258241958 1.1725581501369 0.241611826716505 -691.932640297506 293.276006456909 -2.35932236208751 0.0187473519846726 TLE1 other 1 1 1 1.1725581501369 -2.35932236208751 0.00168087056414587 15.6302342558668 19.5989577538344 0.797503339319608 0.425590888218261 -53.9456922828763 26.5377026467222 -2.03279436057512 0.0426759277184021 MAML3 other 1 1 1 0.797503339319608 -2.03279436057512 0.000236924265836531 14.1202785015443 5.20030847201773 2.71527709894979 0.00688564141347201 43.5802115507395 11.0622893872184 3.93952915398263 9.50796988319061e-05 HIST1H2AG other 1 0.758203248631338 1 2.71527709894979 3.93952915398263 1.13009680982311e-20 52.7487722269272 36.8736721679356 1.43052669087827 0.153280541741565 -309.681961871039 50.2178131578473 -6.1667751420722 1.58806482022707e-09 STRN3 other 9.71996266128853e-17 1.48341134857411e-05 1 1.43052669087827 -6.1667751420722 0.205602133210201 3.01560123612071 67.5532363233957 0.0446403666240979 0.964414404319165 -92.460188634514 86.8194318927976 -1.064971131678 0.28747840690665 ZNF239 other 1 1 1 0.0446403666240979 -1.064971131678 1.74591255598586e-11 46.2018263270199 7.21941356315038 6.39966472662615 4.0096860440795e-10 -3.97235733716257 14.6900423459153 -0.270411564760882 0.78697101509296 ZSCAN16 other 1.30908523447819e-07 1 3.79516784072125e-06 6.39966472662615 -0.270411564760882 0.00323421619273172 336.550158911252 171.578298021121 1.96149607959058 0.0504542076729272 -714.594368837095 379.232518337565 -1.88431723094225 0.060184060207904 MVB12B other 1 1 1 1.96149607959058 -1.88431723094225 0.00235990552304915 109.941139052625 100.433682894685 1.09466401991759 0.274265453714638 -626.530610802486 235.795605615263 -2.65709197237869 0.00816984211074212 C6orf106 other 1 1 1 1.09466401991759 -2.65709197237869 1.15803336382704e-05 12.4618501012827 51.5757607311006 0.241622225724497 0.809185976591169 -327.808943588483 86.2719716651621 -3.79971544942513 0.000165350025402576 PPTC7 other 0.0639466023505291 1 1 0.241622225724497 -3.79971544942513 3.17383877888362e-09 161.603077516326 57.577180228254 2.80672094179814 0.00522865778359387 -30.2484425081783 65.8581402126372 -0.459296943559516 0.646249324947529 NHLRC2 essential 2.2143873160271e-05 1 1 2.80672094179814 -0.459296943559516 5.85100047140541e-15 51.4084574143707 19.69827887673 2.60979437523857 0.00937069472311767 -32.6020353833084 24.7197742295739 -1.31886460938241 0.187905079957783 ZFP28 other 4.69835337853855e-11 1 1 2.60979437523857 -1.31886460938241 0.0489409416037756 -136.63267045456 187.411308089803 -0.729052434707349 0.466360130326217 -664.430320786002 286.367651561865 -2.3202003339489 0.0207897809936819 SCN8A other 1 1 1 -0.729052434707349 -2.3202003339489 2.88156218824025e-16 60.8313526738935 67.6736334935401 0.89889295924535 0.369204695922719 -420.26678983372 87.7164584497567 -4.79119651273251 2.27511519284655e-06 KPNA5 other 2.36259283813818e-12 0.0198048777537292 1 0.89889295924535 -4.79119651273251 1.82792355314475e-13 202.95370729706 34.4317510946965 5.89437658104821 7.60817309015519e-09 -253.293708258028 93.1377361194608 -2.71956050051665 0.00680165775312376 ZNF252P other 1.43053297269109e-09 1 7.09462140656972e-05 5.89437658104821 -2.71956050051665 0.822137443109444 9.34213069211375 80.3894632622427 0.116210885270353 0.907538672394505 92.0797715390065 154.168016711232 0.597268963454844 0.550636451946817 PDLIM7 other 1 1 1 0.116210885270353 0.597268963454844 0.0151508241759971 -6.31728247559643 13.0661543159563 -0.483484453255065 0.628993954217311 24.2195495580356 16.865559863578 1.43603590713517 0.151707557808098 TMEM26 other 1 1 1 -0.483484453255065 1.43603590713517 0.000881268373858793 131.566370604697 106.53853739174 1.23491812282845 0.21752605972811 -395.167903637908 173.418380090179 -2.27869677615728 0.0231678892650873 SRGAP1 other 1 1 1 1.23491812282845 -2.27869677615728 1.97755728526495e-24 340.681070722976 80.2286140896773 4.24637860928487 2.65465985585567e-05 -594.970170217756 118.990845285769 -5.00013399172745 8.3030806226988e-07 NOP9 essential 1.74499654851779e-20 0.00734573542690163 0.22660176529584 4.24637860928487 -5.00013399172745 0.000556018418208725 4.65559215832351 2.38442072590054 1.95250448368973 0.0515149650591212 -3.72131251132863 3.22859251004051 -1.15261139327921 0.249698589274125 SCOC-AS1 other 1 1 1 1.95250448368973 -1.15261139327921 3.7877091253674e-30 300.17548782148 197.695941485856 1.51836949997761 0.129642723410308 -1066.22193305986 241.44869428193 -4.41593580048472 1.26860043624402e-05 AP2A1 other 3.42901307119511e-26 0.106841528740472 1 1.51836949997761 -4.41593580048472 1.04547843522127e-37 99.3921218208135 18.121028908916 5.48490498637802 7.02246827683515e-08 -57.0139623273172 23.817745858787 -2.39375979008875 0.0170984373030049 ZNF585A other 9.70517631415907e-34 1 0.000644311464399625 5.48490498637802 -2.39375979008875 1.39888085295788e-17 69.2346013425981 29.4148649173956 2.35372834575397 0.019027146622453 -120.330408668002 35.6595256530412 -3.37442538744874 0.000805527254569084 FUT11 other 1.16512786242862e-13 1 1 2.35372834575397 -3.37442538744874 4.20182302337874e-07 72.9108829084043 22.9995001755633 3.17010727849952 0.00163074605834661 -111.313789963579 44.5308895774684 -2.49969832221588 0.0127947472770308 WDR5B other 0.00261101282672755 1 1 3.17010727849952 -2.49969832221588 0.442557616204845 -15.5630131580213 82.505763843955 -0.1886294051826 0.850470651156487 -209.168012628621 170.234288821399 -1.22870670813017 0.219841543277095 FAM163B other 1 1 1 -0.1886294051826 -1.22870670813017 6.53758249131074e-34 208.758264305316 32.1780005609779 6.48760832450466 2.36640453128085e-10 14.8564069011083 40.3808329653682 0.367907390960697 0.713120419437738 ZNF470 other 6.000193210525e-30 1 2.24453469791989e-06 6.48760832450466 0.367907390960697 2.90578629532464e-13 103.051515536389 35.3128311816854 2.91824563729219 0.00370303134378734 -84.0768619092045 48.2191713136001 -1.74363971048774 0.0819300156535116 SERTAD1 other 2.26506041720556e-09 1 1 2.91824563729219 -1.74363971048774 0.00563630141257927 989.823697688596 398.487991066271 2.4839486255032 0.0133672033858327 -551.419138646664 776.099779814007 -0.710500315795492 0.477772932193511 ANXA6 other 1 1 1 2.4839486255032 -0.710500315795492 4.99323985471047e-21 -233.156655508863 255.48671843275 -0.912597950058353 0.361959522420016 -2261.7253756855 318.044069214895 -7.11135843931522 4.7513275297572e-12 GMFB other 4.31166261454249e-17 4.54654531322466e-08 1 -0.912597950058353 -7.11135843931522 2.35276783669828e-37 65.2243459621922 16.3959582586193 3.97807465311789 8.13400841738126e-05 -83.3025475865263 21.4532598001779 -3.88297854789581 0.000119172282771327 ZNF420 other 2.18219216853766e-33 0.941222689327938 0.679352383019682 3.97807465311789 -3.88297854789581 1.7939469388888e-57 64.5912701539816 12.0355430809316 5.36671006199267 1.30247451499658e-07 -79.9216711234395 15.4548099689889 -5.17131373881709 3.54317311940514e-07 ZMYM1 other 1.73133819072158e-53 0.00317220289380342 0.00118968022199788 5.36671006199267 -5.17131373881709 0.4865360302153 -8.83321119359962 18.9708032944057 -0.465621358068924 0.641719050099481 -36.24549217485 30.7759143209637 -1.17772267614355 0.239549630034317 DTHD1 other 1 1 1 -0.465621358068924 -1.17772267614355 1.24677796363624e-10 68.1518399789662 29.5718834116342 2.30461614602991 0.0216549994635247 -294.015755357125 60.1727849174232 -4.886191585791 1.44450255074734e-06 ZSCAN26 other 9.14885669716275e-07 0.0126753016456204 1 2.30461614602991 -4.886191585791 0.0144325861437314 166.542412127979 57.6809743171402 2.88730234014944 0.00407886598763449 16.9446645956042 152.11089264363 0.111396786259763 0.911352971128868 MAFG other 1 1 1 2.88730234014944 0.111396786259763 1.00410423256747e-07 142.856187221274 34.0411012760608 4.19657948380585 3.29393114757237e-05 -141.766348518318 71.7415443172198 -1.97607048841142 0.0487855450030972 ARRDC1 other 0.000647546819582763 1 0.2799182689207 4.19657948380585 -1.97607048841142 8.73119362280679e-05 -281.471436117543 131.395298354484 -2.14217281472413 0.0327303530622666 -914.292084174007 210.543677671703 -4.34252927603765 1.75162548205698e-05 KIAA1671 other 0.435511937905603 0.146453406554784 1 -2.14217281472413 -4.34252927603765 6.97135372881358e-09 22.9690146262703 220.942747546133 0.103959124621071 0.917249371016622 -1123.81197414711 290.225061556434 -3.87220858226466 0.000124300699487257 IGF2R other 4.79838277154239e-05 0.98060821825497 1 0.103959124621071 -3.87220858226466 2.228702878268e-25 -382.008605341149 1082.19534197192 -0.352994131951327 0.7242646160409 -9135.46201780411 1281.79951215814 -7.12705998961017 4.3169743782154e-12 DYNC1H1 essential 1.97596797187241e-21 4.13307126970343e-08 1 -0.352994131951327 -7.12705998961017 3.5405323550102e-05 -219.908564316707 294.134182828239 -0.747647084749493 0.455074259154886 681.873194038958 379.493595177231 1.79679763428026 0.0730565919370608 SLC6A17 other 0.185700922020285 1 1 -0.747647084749493 1.79679763428026 3.6464704666925e-14 973.884943181802 492.203919085239 1.9786208630597 0.0484861596037347 -3860.63449928977 752.0959211834 -5.13316771245771 4.29623708498191e-07 PCBP2 essential 2.89420360941384e-10 0.00383739896430585 1 1.9786208630597 -5.13316771245771 1.065105823357e-07 282.343770630444 196.24589092223 1.43872449661804 0.150942774899995 -513.301939602256 232.310361071842 -2.20955250223866 0.0276528703442734 SLC25A29 other 0.000684969555000884 1 1 1.43872449661804 -2.20955250223866 8.65842366110551e-36 11.8314213681724 32.5392546165562 0.363604560325498 0.716328755330774 -246.406824368609 40.8066988517091 -6.03839152155012 3.32409609984288e-09 ZNF772 other 7.99692009339705e-32 3.09207419207385e-05 1 0.363604560325498 -6.03839152155012 0.00986228383837716 -38.728155339805 36.1600696537364 -1.0710199319487 0.284751620946173 21.3823918799658 41.3857858800517 0.516660283845722 0.605654684504442 ACSL5 other 1 1 1 -1.0710199319487 0.516660283845722 0.0246285137301748 43.8558438396746 103.172296288679 0.425073836846323 0.670991599133388 -145.559948305691 133.120827989566 -1.0934423298291 0.274800634147672 LRRC8B other 1 1 1 0.425073836846323 -1.0934423298291 0.850727863600178 -7.64530597141693 18.6537861851183 -0.409852771740046 0.682115248945099 -12.2463902470501 21.6455814965833 -0.565768595728564 0.57184214593959 NEK5 other 1 1 1 -0.409852771740046 -0.565768595728564 3.35862414577886e-20 64.5980861243984 187.014272827806 0.345417946703337 0.729948707232124 -971.010495446825 212.091026700644 -4.57827240761751 6.14272558502937e-06 ADGRA1 other 2.87531813120128e-16 0.0525264464775861 1 0.345417946703337 -4.57827240761751 6.05965579608245e-08 24.4435828322619 4.44258167439157 5.5021122004717 6.44109304960879e-08 2.79475430230146 9.36239607638977 0.298508445861344 0.765458659806701 CYSRT1 other 0.000395210751020497 1 0.000591549985676071 5.5021122004717 0.298508445861344 1.46010715388809e-08 -186.269365983752 201.239494069772 -0.925610386990787 0.355161703794895 -2386.72538085425 407.13660411385 -5.86222254825026 9.03779752449947e-09 TBC1D9B other 9.89514618189962e-05 8.34911735313261e-05 1 -0.925610386990787 -5.86222254825026 0.0956036562450043 6.04603730609287 3.4057372595608 1.7752506565561 0.0765556565443664 -3.08894563985765 7.24481083089975 -0.426366638405937 0.67005161535055 HIST1H4J other 1 1 1 1.7752506565561 -0.426366638405937 0.647496704393548 0.764471574020333 5.11627786444045 0.149419479214298 0.881291416720063 -2.39730375896128 6.56898941113994 -0.364942551878047 0.715330435481955 FAM110D other 1 1 1 0.149419479214298 -0.364942551878047 0.0073599071082389 33.4483607786089 205.702487646558 0.162605523935523 0.870904028030588 471.080235616975 241.163920267314 1.95336116237791 0.0514131001684851 SERPINA1 other 1 1 1 0.162605523935523 1.95336116237791 0.96991061882575 -2.2405662524466 12.4121122061642 -0.18051450190193 0.856832161790228 2.39273521780693 28.2544448262721 0.0846852674869077 0.932550301970288 C6orf141 other 1 1 1 -0.18051450190193 0.0846852674869077 0.00950830058517711 5.98810658205515 2.08193691433747 2.87621903469671 0.00422160434992931 1.22907944488934 4.23648915650894 0.290117453269292 0.771863996944448 ZNF165 other 1 1 1 2.87621903469671 0.290117453269292 0.0242371067479921 35.1820131349691 24.8557100232109 1.41544993492905 0.157648866604924 -103.572744940356 54.4408885491345 -1.90248079523681 0.0577654079931468 RAMP2-AS1 other 1 1 1 1.41544993492905 -1.90248079523681 0.509829134738506 38.9750176578238 77.9716443889 0.499861429924803 0.617424245750105 -96.186007775002 151.081525720698 -0.636649698341144 0.524686382885677 BLM ts 1 1 1 0.499861429924803 -0.636649698341144 2.21821341846077e-27 35.5904723970363 35.2368853666407 1.01003457106712 0.313036366508835 -245.433673225525 45.024694729562 -5.45109022281456 8.37556011803227e-08 DDI2 other 1.98840650830823e-23 0.000761840948336215 1 1.01003457106712 -5.45109022281456 0.199393729751219 8.87768764837151 33.0665156003219 0.268479683667822 0.78845651533678 103.200533054405 64.3257347538527 1.60434285670128 0.109359274423246 SVIL other 1 1 1 0.268479683667822 1.60434285670128 8.40960272644958e-32 31.4986445806862 72.0527104125121 0.437161133847039 0.662209948210978 -609.853127008394 92.5227004455017 -6.59138918418852 1.25499433550603e-10 TRIM33 other 7.66030712352292e-28 1.18546764931899e-06 1 0.437161133847039 -6.59138918418852 4.27067498609922e-05 227.507134616442 331.107537796325 0.687109499622411 0.492377366876299 -1471.27203269462 493.737544389077 -2.97986663038779 0.00304420605302341 LRP10 other 0.221776152028132 1 1 0.687109499622411 -2.97986663038779 0.598245372063953 -8.55862040098563 67.6023061754083 -0.126602491618829 0.89931365628849 -137.703214599638 141.539445055875 -0.97289638620017 0.331146722245135 UAP1L1 other 1 1 1 -0.126602491618829 -0.97289638620017 0.0145394762191568 -9.14183381088844 5.66725279377271 -1.61309794066954 0.107445095646827 -27.8204052394598 9.53058591021575 -2.91906557493379 0.00369222470711617 FBXL22 other 1 1 1 -1.61309794066954 -2.91906557493379 2.28074268756834e-24 206.131231293785 20.2900071472005 10.1592488262 6.92554515104622e-22 -23.5667929888163 55.0453298206696 -0.428134286152773 0.668766720027378 ZNF517 other 2.01138697616652e-20 1 6.78357147544977e-18 10.1592488262 -0.428134286152773 6.05888379303568e-05 -180.538773123629 99.816821853081 -1.80870087598423 0.0711846543404032 -421.215118594661 121.171818710484 -3.47618054327524 0.000559480342515215 DACT3 other 0.308518362741377 1 1 -1.80870087598423 -3.47618054327524 0.1756830291613 5.77153092136273 63.6458470170475 0.0906819720667215 0.927786750431561 -193.845014993225 122.204964785222 -1.58622863918754 0.113409098706195 ADARB1 other 1 1 1 0.0906819720667215 -1.58622863918754 1.43328762294579e-08 -10.0313260952704 153.229877449153 -0.0654658625475906 0.947833023228249 -1305.78553963495 254.202939697253 -5.13678378853565 4.21904517450661e-07 HTT other 9.72236828242068e-05 0.00377013876793911 1 -0.0654658625475906 -5.13678378853565 4.69612885233013e-06 -9.59770030586566 72.2069720194146 -0.132919301799348 0.894318384619166 -214.700459749432 88.1581500784306 -2.43540114621759 0.0152742167516513 C5AR1 other 0.0269792602566366 1 1 -0.132919301799348 -2.43540114621759 0.025248095682685 39.8384412645412 54.4737540896125 0.731332766216271 0.464969683915608 -87.4550876926687 71.7060205269716 -1.21963381944719 0.223264577658885 DCHS2 other 1 1 1 0.731332766216271 -1.21963381944719 0.278621460974615 -177.280283831729 134.250068636942 -1.3205228543395 0.187353254955285 -398.245127401743 296.148484411425 -1.34474815291805 0.179405701335301 VEPH1 other 1 1 1 -1.3205228543395 -1.34474815291805 0.000248751998226083 45.3554267870216 31.94579610372 1.41976198181958 0.156389944368321 -83.3818893793313 21.3212803308335 -3.910735569606 0.000106650145207816 SHPK other 1 0.846047755194454 1 1.41976198181958 -3.910735569606 1.22598401328554e-31 38.7541438324234 19.1228157758298 2.02659191442959 0.0433095547837607 -127.799865843425 24.6737269707327 -5.17959309491499 3.39816824037877e-07 IPP other 1.11564545208984e-27 0.00304339947608323 1 2.02659191442959 -5.17959309491499 0.36162477520789 -97.3889589758235 283.576443904333 -0.343431060898269 0.731438980807886 203.925173912618 358.306204662924 0.569136596739819 0.56955517435407 OPALIN other 1 1 1 -0.343431060898269 0.569136596739819 8.49906759179994e-10 -523.671667155 225.776872256524 -2.31942121405603 0.0208323596896599 -1610.24052153531 287.553530904895 -5.59979394608051 3.79932101858128e-08 MAP3K5 other 6.06748435378598e-06 0.000347979812091859 1 -2.31942121405603 -5.59979394608051 0.0283316027933821 -223.604753822743 142.611178423844 -1.56793286679242 0.117620584042444 27.7280496258895 186.252487785974 0.1488734456946 0.881722169674861 OGDHL other 1 1 1 -1.56793286679242 0.1488734456946 0.0315040215928213 448.658896001935 170.086015770038 2.63783529745642 0.00864072843632036 374.08743291978 326.184833900961 1.1468572233906 0.252066735003096 HNRNPAB other 1 1 1 2.63783529745642 1.1468572233906 1.82998149368005e-11 777.855191867325 107.967848913622 7.20450763532054 2.57944366666524e-12 383.85202175134 407.538990502558 0.941878030560932 0.346776660234138 PDGFA other 1.37157112951319e-07 1 2.47910330803196e-08 7.20450763532054 0.941878030560932 0.43660472390052 -14.2986465147755 22.6375321404818 -0.631634509717861 0.527957513063795 4.40513121287319 27.4967867039303 0.160205309089572 0.872793713102468 COL13A1 other 1 1 1 -0.631634509717861 0.160205309089572 0.113429163834967 6.83344682123162 3.26703338127533 2.09163666964556 0.0370490646967406 4.59987211851462 6.45602488277289 0.712492935209839 0.476540692666425 ZNF695 other 1 1 1 2.09163666964556 0.712492935209839 0.508896575561219 -1.21117766726948 8.55678241111953 -0.141545923347958 0.887503911650631 -20.3126130198925 18.0404280120729 -1.12594961750902 0.260804804501384 PCDHB11 other 1 1 1 -0.141545923347958 -1.12594961750902 2.06691709889797e-19 43.7160840798644 11.8619616077652 3.68540090799539 0.000257237033463632 -12.181363077463 14.6863534336642 -0.829434150041678 0.407314746283095 ZNF628 other 1.75563938380393e-15 1 1 3.68540090799539 -0.829434150041678 2.87381288316657e-27 17.5330059154005 5.25231866033727 3.33814588360765 0.00091591427760423 -28.7034412540985 7.55093781874375 -3.80130812133663 0.000164471605870978 ZNF665 other 2.57436158074061e-23 1 1 3.33814588360765 -3.80130812133663 1.29692117606882e-12 68.4565136895291 29.2199709138177 2.34279883068457 0.0195864362464065 -127.359737075841 40.0728822758731 -3.17820256100024 0.00158689652289948 RPF2 essential 9.96554231691283e-09 1 1 2.34279883068457 -3.17820256100024 0.396567250650952 13.9095082705075 10.2476581428569 1.35733531277124 0.175373661717823 5.38091594463825 24.2423460191053 0.221963498928593 0.8244457520446 FAM177B other 1 1 1 1.35733531277124 0.221963498928593 2.61738923391341e-32 309.418310769825 70.3153063170283 4.40044034473464 1.35851626678711e-05 -320.030024846549 93.2553257093683 -3.4317613756873 0.000656613775874374 MIB2 other 2.39019984840972e-28 1 0.11741656093841 4.40044034473464 -3.4317613756873 0.0477013779117441 -494.483653568883 488.449067723084 -1.01235458565604 0.311930011591264 -1798.0209977678 751.912572572165 -2.39126337735926 0.017213593996867 MYO5A other 1 1 1 -1.01235458565604 -2.39126337735926 1.33801226915849e-12 824.259791726926 117.582071823538 7.01008052455431 9.11080303078024e-12 4.94477870986417 259.764018280504 0.0190356568342141 0.984821368452487 ATG7 other 1.02745962148681e-08 1 8.73088254439671e-08 7.01008052455431 0.0190356568342141 0.0262835941440051 -350.527998950709 354.997323950166 -0.987410257210605 0.323986695572989 -874.103269758974 404.383423040931 -2.16157047978324 0.0311923794662809 SIPA1L1 other 1 1 1 -0.987410257210605 -2.16157047978324 4.87550477801157e-06 105.35689723888 32.5768949998522 3.23409880651173 0.00131262021495322 -43.1856466248345 51.8261494205165 -0.833279089951809 0.405141505106758 PIGN other 0.0279756464162304 1 1 3.23409880651173 -0.833279089951809 0.00696672828821731 32.1918561137817 10.2781957429594 3.13205322401388 0.00185253332419127 -5.15214675823991 7.63264553545975 -0.67501454565184 0.500023501646854 ZNF624 other 1 1 1 3.13205322401388 -0.67501454565184 9.43366598933609e-30 57.7564247954755 21.3254961728708 2.70832736210613 0.00702779365682913 -116.881695069322 27.3986504815034 -4.26596540396132 2.44172058395749e-05 HHLA3 other 8.53180752075556e-26 0.202613974056792 1 2.70832736210613 -4.26596540396132 1.1276903022087e-13 151.246043853039 30.3548672621668 4.98259612031138 9.07746511731423e-07 -64.4738738076427 35.3322577789084 -1.82478782451685 0.0687203369068687 TOPORS other 8.8737949880803e-10 1 0.00815247142185991 4.98259612031138 -1.82478782451685 2.42348383677987e-06 19.5408973697779 15.9281781177792 1.22681308717701 0.220553404184363 82.5780299123258 20.4207221904049 4.04383494091736 6.21571484722411e-05 ENPP1 other 0.0142646258632863 0.502043288210291 1 1.22681308717701 4.04383494091736 1.55274391047447e-10 273.558536663365 91.5935442588528 2.98665739902215 0.00297873589118329 -260.149387611523 111.679389782687 -2.32943059697711 0.0202900710490632 FAR1 other 1.13567689612103e-06 1 1 2.98665739902215 -2.32943059697711 0.00295850372466832 24.5501943745702 67.7880363860679 0.362161167123228 0.717406664159678 -407.528222425493 145.494948962551 -2.80097848984699 0.00532090982982321 C5orf42 other 1 1 1 0.362161167123228 -2.80097848984699 6.41289617410031e-22 81.4252864636655 18.4971342985666 4.40204872545988 1.35380056681198e-05 -11.336597454127 23.0730438848667 -0.491335148959801 0.62343952695265 ZNF841 other 5.57793709223245e-18 1 0.117036059000896 4.40204872545988 -0.491335148959801 0.0286182947677934 16.9056431880896 17.7942598748118 0.950061610149909 0.342606071471406 -33.6915143942936 26.3652085774228 -1.2778777871359 0.20197090439391 MYH6 other 1 1 1 0.950061610149909 -1.2778777871359 1.34333706621771e-55 62.0404533815024 17.8835914216308 3.46912719703842 0.000574586446249458 -119.093760615878 22.3044876455701 -5.33945287192157 1.50987668414378e-07 ZNF615 other 1.29349926106103e-51 0.00136341864578183 1 3.46912719703842 -5.33945287192157 0.607297834061726 -70.718788279175 70.774102446846 -0.999218440562881 0.318240582281787 -57.0233838446403 170.119011173047 -0.335197009737116 0.737636955951404 MPEG1 other 1 1 1 -0.999218440562881 -0.335197009737116 0.647805993859613 -10.1863219417529 12.6780925094349 -0.803458559256636 0.422146540868471 -3.01572255750576 14.5978325998866 -0.206587007822599 0.836428625573251 PDCD1LG2 other 1 1 1 -0.803458559256636 -0.206587007822599 0.128679781189527 24.3063163506291 15.4029389632803 1.57803107631433 0.115282034322437 -18.0913489097282 28.3636047570297 -0.637836730017343 0.523914032722478 DNAH10 other 1 1 1 1.57803107631433 -0.637836730017343 0.0130649346334498 13.6587344195054 977.401964965121 0.0139745313689776 0.988856677623985 -5946.29029923906 2160.32630905542 -2.75249635868158 0.00616053924417465 SPTAN1 other 1 1 1 0.0139745313689776 -2.75249635868158 0.00664359745613176 1293.24441534608 621.066498894858 2.08229620764815 0.037897911840409 -1131.54086160899 1178.97471470022 -0.9597668614095 0.337704492623606 NMB other 1 1 1 2.08229620764815 -0.9597668614095 9.655428348112e-06 313.877094749389 148.552372696288 2.11290529429041 0.0351740281905078 -289.092122182596 180.783107657465 -1.59911025940735 0.11051717151114 PARVA other 0.0537807358989838 1 1 2.11290529429041 -1.59911025940735 0.0221402698858294 140.02911448732 59.7097620562052 2.3451628287433 0.0194652813802718 9.12223114753164 96.8600232591983 0.0941795267085624 0.925009713504552 FAM114A1 other 1 1 1 2.3451628287433 0.0941795267085624 6.72866702659404e-16 5.99238160692986 4.62230333335269 1.29640596360071 0.195519835592581 -15.8496680325743 5.76868305902158 -2.74753663364937 0.00625285555397598 ZNF460 other 5.48520936007946e-12 1 1 1.29640596360071 -2.74753663364937 0.00148617594459896 217.248394937783 123.391499125309 1.76064312758822 0.0789982589977373 -618.386007556339 269.079799433157 -2.29815099037174 0.0220246076537283 PHF2 other 1 1 1 1.76064312758822 -2.29815099037174 4.26187822782452e-06 3910.46038906124 4423.29230531203 0.884061038508597 0.377148271835146 -12042.7013662339 5370.7199859034 -2.2422880727058 0.025442419209982 PSAP other 0.0245867754963197 1 1 0.884061038508597 -2.2422880727058 0.00119413242744958 2.17451010150425 48.6271428415825 0.0447180314210187 0.964352487388588 118.776698117576 58.104552134043 2.04418920300025 0.0415337163619916 CFAP43 other 1 1 1 0.0447180314210187 2.04418920300025 1.4082204459877e-06 15.7978457232516 4.30994825568581 3.66543744519685 0.000277209976060832 -21.2779214904656 10.1187851508496 -2.10281384309054 0.0360520801868186 LHFPL5 other 0.00842819996909468 1 1 3.66543744519685 -2.10281384309054 3.022889362495e-05 23.4733227345002 14.5348787264617 1.61496515906703 0.107039973639432 -90.4515557574374 28.870071288944 -3.13305619692309 0.00184635476983788 TXNRD3 other 0.159971305063236 1 1 1.61496515906703 -3.13305619692309 0.440400045852326 6.37880478087646 11.3526546817291 0.56187781269719 0.57448799082656 41.5375009054689 33.3448159323382 1.24569591236476 0.213545042627343 CFD other 1 1 1 0.56187781269719 1.24569591236476 0.321086416788485 10.2159212032687 7.15549369730783 1.4277031935773 0.154094793858401 -0.832458252733811 14.9939401657478 -0.0555196461724905 0.955749969264734 MAP1LC3C other 1 1 1 1.4277031935773 -0.0555196461724905 5.12778858630474e-26 124.682154732032 70.4253928812422 1.77041475568738 0.0773551992191486 -359.806903936367 81.8206643521011 -4.39750650750036 1.37691366050003e-05 MCMBP essential 4.5616807263767e-22 0.115715824028423 1 1.77041475568738 -4.39750650750036 3.63217749347716e-12 -27.1032675824382 15.2089696223569 -1.78205810488285 0.0754371987081147 -125.562008739754 20.0274652460424 -6.2694907816438 8.73827110161901e-10 KLHDC1 other 2.76662959678155e-08 8.18863384932717e-06 1 -1.78205810488285 -6.2694907816438 5.66551546156621e-53 142.082350147825 36.4665914992328 3.89623335514684 0.000113009270637671 -287.428032550647 47.0692622398324 -6.10649113398279 2.25170737537208e-09 TAF13 other 5.43719518846509e-49 2.0981409323717e-05 0.936507825774376 3.89623335514684 -6.10649113398279 1.48790563136394e-39 64.5271227414506 16.0389439781399 4.02315282286647 6.76881798381159e-05 -105.115888847562 22.072910932138 -4.76221234121478 2.61070778054393e-06 ZNF780A other 1.38806716349942e-35 0.022673997074024 0.567497699762763 4.02315282286647 -4.76221234121478 3.21878169891547e-48 349.3711953664 44.5676311729281 7.83912418433897 3.49737163056933e-14 -122.119116622701 59.1384027971756 -2.06497150492089 0.0395149881151946 ATAD3A other 3.0613832738385e-44 1 3.38405678973888e-10 7.83912418433897 -2.06497150492089 9.38174975797059e-38 54.2271000526247 9.12154238696421 5.94494853525231 5.67135124351448e-09 -23.0632581239311 11.9841741965843 -1.92447620884087 0.0549453693134868 ZNF461 other 8.71283100022728e-34 1 5.29817633169123e-05 5.94494853525231 -1.92447620884087 0.000707766423420659 85.8129541071111 27.2092078251117 3.15382037796461 0.00172263462131985 -51.126592512351 59.335110086319 -0.861658340870581 0.389348109984159 CCDC180 other 1 1 1 3.15382037796461 -0.861658340870581 1.12802306148237e-59 134.555137526522 27.7231327771633 4.85353291808927 1.69214789202964e-06 -220.522813699541 36.6010414987856 -6.02504203895012 3.59934979821795e-09 ZNF181 other 1.09158791659649e-55 3.34667544238305e-05 0.0150854984574442 4.85353291808927 -6.02504203895012 1.37010554042217e-20 921.338590978004 94.10746369688 9.7902818202139 1.35404981845732e-20 284.879047399122 276.075630215401 1.03188770112325 0.302695466567791 GPAA1 other 1.17733169088477e-16 1 1.32426072245125e-16 9.7902818202139 1.03188770112325 0.790409422349236 22.7133101038592 64.8360892800725 0.350318940516978 0.726267757825286 -52.4229240261426 133.776417965525 -0.39186969440049 0.695345087029516 ADAMTSL2 other 1 1 1 0.350318940516978 -0.39186969440049 1.12444687912572e-54 66.3305773911328 9.37490002331686 7.07533704105197 5.98251638274844e-12 -36.0758535061177 12.3170435644254 -2.92893772092463 0.00357958717876477 ZNF790 other 1.08160545303103e-50 1 5.73902796597057e-08 7.07533704105197 -2.92893772092463 0.302620893916272 59.8063642170743 67.1679250778704 0.89040065102113 0.373742974041087 -62.6605690718213 47.7446616115784 -1.31240995237519 0.19007389833166 MYO1C other 1 1 1 0.89040065102113 -1.31240995237519 9.3283388119984e-06 -22.5258380026519 42.7470345895611 -0.526956740249599 0.598491630244373 -400.958520601103 87.2406695169869 -4.59600462514827 5.64788590915023e-06 NKIRAS1 other 0.0520614589097631 0.0483797906977808 1 -0.526956740249599 -4.59600462514827 1.89351344518763e-15 122.37386515851 121.860498043154 1.00421274427398 0.315831797926742 -961.540493489742 171.722982957742 -5.59936985095559 3.80800192264325e-08 ADH5 other 1.53412459329102e-11 0.000348736816075669 1 1.00421274427398 -5.59936985095559 0.000106385711457358 35.199541007368 11.6783916548684 3.01407437322023 0.0027283550710818 100.71043201675 24.8427086121115 4.05392316873413 5.96736557760929e-05 HIST1H2BK other 0.525651800310808 0.482759875228592 1 3.01407437322023 4.05392316873413 8.48703156573018e-08 415.667169843874 93.9390193566562 4.42486171018796 1.22005695835895e-05 -327.681917248914 199.609635066186 -1.64161372841677 0.101389505470991 SPG7 other 0.000549959645459315 1 0.105656932593885 4.42486171018796 -1.64161372841677 0.0210863610272989 46.6591520475572 74.8132882360542 0.623674659244173 0.533165921518399 -87.4342673687367 95.5898131529049 -0.914681852436278 0.360861935433575 HES5 other 1 1 1 0.623674659244173 -0.914681852436278 1.61703872299765e-19 93.9731649072322 40.6087497833399 2.31411125455986 0.0211288755286225 -189.237163177116 56.2657160063744 -3.36327654935871 0.000838713705335399 ZNF677 other 1.37464461842031e-15 1 1 2.31411125455986 -3.36327654935871 0.00408378090517617 -79.4696462546702 95.5767073258572 -0.831475036943133 0.406159413330277 -326.167268993428 120.084082737054 -2.71615739204696 0.00686645383854669 ERO1A other 1 1 1 -0.831475036943133 -2.71615739204696 0.0241778614618497 31.6057543855947 12.4228921436518 2.54415429355117 0.011296685277075 3.65580571690986 26.0026785966025 0.140593427839681 0.888255773362798 ZNF311 other 1 1 1 2.54415429355117 0.140593427839681 3.66761268679468e-32 85.3983426420592 18.1807489662681 4.69718507199588 3.54037234820245e-06 -90.1669545288971 26.8477981142736 -3.35844876906162 0.000852630168511455 ZNF347 other 3.34522953162543e-28 1 0.0312685685793241 4.69718507199588 -3.35844876906162 0.228803080822527 -43.0164901647947 38.3011407746333 -1.12311250513155 0.262004940634632 72.7045048131992 88.3979113040116 0.822468582579505 0.411257781225713 PLCG2 other 1 1 1 -1.12311250513155 0.822468582579505 0.10621214631881 32.8202130783339 37.1400951941057 0.883686832432853 0.37735229601296 -110.238352992017 75.8453882461774 -1.45346151613342 0.146815037317187 FCHSD1 other 1 1 1 0.883686832432853 -1.45346151613342 6.21317398376661e-39 67.1187938306734 17.3551279515208 3.8673753381802 0.000126745966730463 -65.9386087601292 21.7793060689057 -3.02758079396615 0.00261107586445808 ZNF71 other 5.78260102669158e-35 1 1 3.8673753381802 -3.02758079396615 5.60117222773701e-07 1500.41137641593 290.484389831945 5.16520484038391 3.65398834737773e-07 155.821082226387 642.045806283491 0.242694649978892 0.808355558315423 RPL12 essential 0.00345872385062761 1 0.00331087884155896 5.16520484038391 0.242694649978892 0.00475411573130626 88.0374077934244 60.1008303722676 1.4648284765471 0.143688408588125 -255.707527072849 125.374060979266 -2.03955686746987 0.041996820285735 VPS13A other 1 1 1 1.4648284765471 -2.03955686746987 0.733059642920996 -5014.72865364221 18158.3942757884 -0.276165864529586 0.782552740443363 -19672.5177154428 27072.6087150755 -0.726657631057476 0.467829265909969 MBP other 1 1 1 -0.276165864529586 -0.726657631057476 0.402011388214964 -359.103298115365 266.115625672289 -1.34942582649238 0.177902116762515 -299.667285360747 460.688865403628 -0.650476509993781 0.515727873722942 ELOVL2 other 1 1 1 -1.34942582649238 -0.650476509993781 0.0176573541192281 25.5717976027963 16.9426660920079 1.50931367377056 0.131942952351096 -43.6335668531829 33.2174814256176 -1.31357240165512 0.189680934182099 GOLGA6L9 other 1 1 1 1.50931367377056 -1.31357240165512 3.43639464423062e-26 355.810974168228 115.470231808261 3.08140867647216 0.00219015621902556 -501.432892734497 148.275028195375 -3.38177573686773 0.000784817932120603 C1orf122 other 3.06045307015179e-22 1 1 3.08140867647216 -3.38177573686773 4.49708283461714e-22 51.2642834795952 26.60218665171 1.92707028752089 0.0546173681286905 -132.877721984036 34.1580996840541 -3.89007946030635 0.000115777331615835 SNHG12 other 3.91650944066807e-18 0.915219806423175 1 1.92707028752089 -3.89007946030635 0.00475355392215773 9.33794394815787 100.800515664237 0.0926378589099901 0.926233914225919 -231.082461979897 118.078691851481 -1.95702085072684 0.0509842234362955 PCDH20 other 1 1 1 0.0926378589099901 -1.95702085072684 1.34090187512623e-08 224.039302353365 40.1671212340576 5.57767884454219 4.27868998601414e-08 -16.6537092342608 83.0892493463825 -0.200431576470679 0.841236309560848 NOL8 essential 9.11008733960763e-05 1 0.000394024560812042 5.57767884454219 -0.200431576470679 0.177604479650844 55.855211253314 30.3389840634573 1.8410376279076 0.0663047504208442 43.2494006773299 46.3637930741995 0.932827057702431 0.351432746396278 IRAK4 other 1 1 1 1.8410376279076 0.932827057702431 7.26507164291244e-11 198.229607810564 69.0180156275683 2.87214296163252 0.00427494551095191 -374.217391026541 109.898573546458 -3.40511599878361 0.000722298614781655 MRPL42 other 5.36598191545513e-07 1 1 2.87214296163252 -3.40511599878361 0.233111134473546 13.5715701810111 8.76681333484046 1.54806195394578 0.122329590767609 9.24801781488452 10.5722187695167 0.87474710999641 0.382190919093527 ENTPD7 other 1 1 1 1.54806195394578 0.87474710999641 0.000110552246639684 262.979014018636 103.897121788135 2.53114821173676 0.0117195145440642 -461.171943541716 186.36560113703 -2.47455507200939 0.0137196849731326 ZNF84 other 0.545243680426919 1 1 2.53114821173676 -2.47455507200939 2.22450253090683e-15 84.5252629840423 27.3070853882107 3.09536011560335 0.00209211301553559 -29.8759707425927 34.2682215988771 -0.871827289209888 0.383781331936795 ZNF667 other 1.79895519674435e-11 1 1 3.09536011560335 -0.871827289209888 0.000275501914975591 104.563534243266 35.5656538710273 2.94001439204374 0.00345569378103625 -76.2622383655725 68.20652978423 -1.11810758598666 0.264133920355479 GRK6 other 1 1 1 2.94001439204374 -1.11810758598666 0.000830062787089623 28.6717506372573 19.2765558303494 1.48738970226807 0.137636399425486 -71.0428750715289 33.5149488975118 -2.11973693556201 0.0345939439527061 PRIM1 essential 1 1 1 1.48738970226807 -2.11973693556201 5.00529720736029e-34 52.0654948444474 64.7618660570943 0.803952974402348 0.421860243587498 -544.148949752212 78.2023067075079 -6.9582212170216 1.26297334638238e-11 MARCH5 other 4.59586389579821e-30 1.20449768044488e-07 1 0.803952974402348 -6.9582212170216 2.04073276386309e-15 61.278908114811 15.1499246643474 4.04483253035705 6.18795289430596e-05 -130.54456329579 30.2622790158166 -4.31377171651746 1.98517873388869e-05 ZBTB14 other 1.65176909907079e-11 0.165365388532928 0.519540525005928 4.04483253035705 -4.31377171651746 0.0352298599729942 41.1686012107973 25.4455674990129 1.61790854978551 0.106402179512081 144.955687559743 57.9232906561212 2.50254579665225 0.0126937537385639 CD2AP other 1 1 1 1.61790854978551 2.50254579665225 3.10647658421182e-05 138.188631519478 34.9252276183147 3.95669952475878 8.86908180474714e-05 24.740524126242 55.1554500276258 0.448559917720737 0.653971993399257 SFI1 other 0.164146222709753 1 0.739237968425674 3.95669952475878 0.448559917720737 2.35185941238384e-07 58.6102321406249 43.9890612215112 1.33238197208818 0.183433857574058 -74.681451475451 55.0931713105005 -1.3555482412612 0.175947933699997 ZNF649 other 0.00148425847515544 1 1 1.33238197208818 -1.3555482412612 5.97347129832927e-35 47.5134837555527 14.8173945029758 3.20660179129404 0.0014446097574738 -240.179824822796 26.9828203382998 -8.90121276469687 1.61370145197028e-17 ZNF248 other 5.49917767724192e-31 1.57820002002693e-13 1 3.20660179129404 -8.90121276469687 0.565392271922402 17.1560031595577 16.3774916167396 1.04753545665212 0.295439767171326 21.1141390205374 34.5149081259498 0.611739684877297 0.541032546690329 TOR4A other 1 1 1 1.04753545665212 0.611739684877297 0.222946164711654 -14.8650972400988 221.337857767532 -0.0671602110458273 0.946484806175767 -742.863238238234 457.847041990239 -1.62251400600743 0.105412853502911 LPAR1 other 1 1 1 -0.0671602110458273 -1.62251400600743 0.350714903406194 -6.85287978962197 6.4993197941551 -1.0543995382078 0.292286665859905 -14.4810632082063 10.1136268203929 -1.43183681436683 0.152910292283526 MB other 1 1 1 -1.0543995382078 -1.43183681436683 3.69633626690479e-78 267.855152978136 31.3811479349556 8.53554349042057 2.33737487497406e-16 -97.1372472020411 39.1998959851551 -2.47799757526976 0.0135898847319463 ZNF544 other 3.62536661058022e-74 1 2.27286332842478e-12 8.53554349042057 -2.47799757526976 2.27279900039867e-06 170.828452951057 191.621690426962 0.891488080344273 0.373157965832573 -416.56817320263 218.303549075719 -1.90820614216466 0.0570195812640315 TMEM229B other 0.0133958773083498 1 1 0.891488080344273 -1.90820614216466 1.17105801275109e-14 239.874849229911 103.281844674017 2.32252677115726 0.020663094484988 -828.91290128039 165.530161317154 -5.00762456028906 8.00990915988834e-07 ZNF770 other 9.35909563790668e-11 0.00708957059741717 1 2.32252677115726 -5.00762456028906 0.182222960480019 -4.60952682495921 4.13428453101375 -1.11495152072393 0.26549250077197 -11.8870462213045 6.42942273231022 -1.84885124469537 0.0651639309937607 ZNF876P other 1 1 1 -1.11495152072393 -1.84885124469537 3.21035391079335e-75 61.1222432002295 31.0514321862746 1.96841945432864 0.0496500111514965 -419.508122349359 39.8753975614961 -10.5204749796511 3.13783196333234e-23 MIER1 other 3.14389958483993e-71 3.08511638634835e-19 1 1.96841945432864 -10.5204749796511 2.13550469774056e-18 138.863202539778 102.584004105302 1.35365356178957 0.17654823058291 -473.33499419331 129.016210867008 -3.66880247848259 0.000273838145922823 MAN1A2 other 1.79724075361846e-14 1 1 1.35365356178957 -3.66880247848259 0.0362255430267589 40.0055861482415 51.0694209813415 0.783356955679168 0.433842833944008 -83.6806789285601 63.5887340612544 -1.31596705240194 0.188876572677306 SVIP other 1 1 1 0.783356955679168 -1.31596705240194 7.90625601124455e-32 274.683257868944 22.8970487097596 11.9964481602323 8.11398550091959e-29 -15.8145646880259 62.1180460413271 -0.254588894787586 0.79916178171007 ZNF251 other 7.20338985184491e-28 1 7.97523634885386e-25 11.9964481602323 -0.254588894787586 1.58759250997933e-14 342.830324266533 94.0156599246287 3.64652361682486 0.000298623526814001 -454.051208575844 132.883624488974 -3.41690866968728 0.000694073326678825 TFDP1 other 1.26642254521051e-10 1 1 3.64652361682486 -3.41690866968728 5.68180492845839e-59 69.2887747515098 12.6078854566405 5.49566975285422 6.62563129047411e-08 -88.3021194926311 16.8053306188606 -5.25441132312684 2.325941799207e-07 ZNF607 other 5.49203264384788e-55 0.00209148686584694 0.000608232952465523 5.49566975285422 -5.25441132312684 1.38847700311964e-07 198.479409470415 61.2093395303307 3.24263275822578 0.0012748347443623 -118.54771433664 89.6116372878327 -1.32290534940083 0.186557092573827 HSD17B11 other 0.000886959109592824 1 1 3.24263275822578 -1.32290534940083 9.29242451427046e-80 68.5139733482524 62.0064662945006 1.10494884554208 0.269788351758866 -949.135026779515 80.0055095287899 -11.8633708149558 2.4209394407784e-28 SZT2 other 9.12144390320788e-76 2.38341487944634e-24 1 1.10494884554208 -11.8633708149558 1.31342009221367e-12 9.57601724900635 80.4887974650242 0.118973292564938 0.905351060609751 -344.278029632904 90.7668894071505 -3.79299138575285 0.00016974645497981 RPS6KL1 other 1.00896931483854e-08 1 1 0.118973292564938 -3.79299138575285 2.27082459832319e-09 101.06935918839 84.0571361225469 1.2023888018388 0.22986551846624 -583.12563246436 133.861622057041 -4.35618232846365 1.65179481064931e-05 QRICH1 other 1.59480011540237e-05 0.138222189755134 1 1.2023888018388 -4.35618232846365 0.010750621129812 461.9024302387 164.559043885625 2.80691002652969 0.00522616347042311 -124.960168419703 348.476348525579 -0.358590099294874 0.720075321125375 RPL23A essential 1 1 1 2.80691002652969 -0.358590099294874 0.00445881011181742 23.4133070200161 26.7187102871739 0.876288816652034 0.38135337157063 -38.7340997608837 32.4416071631886 -1.19396365186356 0.233138415301167 SLC29A3 other 1 1 1 0.876288816652034 -1.19396365186356 2.15867098958782e-08 17.8768057219368 25.0258497040526 0.714333616374348 0.475402291195228 -104.602273070457 31.4428723326976 -3.32674038057523 0.00095290360690929 STYX other 0.000144954756950822 1 1 0.714333616374348 -3.32674038057523 2.91902957294874e-07 5.94073553525396 16.7374425157285 0.354936874595467 0.722807724557882 -127.237676940066 28.7425292491512 -4.42680864433055 1.20894072713146e-05 TMEM116 other 0.00183081534815345 0.10198623974081 1 0.354936874595467 -4.42680864433055 0.00485511858657533 55.7919764061006 16.9887723872722 3.28404990862668 0.00110535362398233 44.52092202211 63.2620365373805 0.703754170098576 0.481959826975345 CARD11 og 1 1 1 3.28404990862668 0.703754170098576 1.74168878912172e-15 0.468505689120614 5.74977792661678 0.081482397250825 0.935095714030077 -38.6627232634907 7.38961566117791 -5.2320343893674 2.60969089511434e-07 ZNF485 other 1.41181293246206e-11 0.00234428533108121 1 0.081482397250825 -5.2320343893674 0.456289925181128 -444.93535293221 469.877771349401 -0.946917219885586 0.344204265950712 -276.255647169425 589.659253782518 -0.468500486335648 0.639660324891073 PEG3 other 1 1 1 -0.946917219885586 -0.468500486335648 1.03477534312718e-10 183.293678104416 45.6828466295596 4.01230859343633 7.07323730771445e-05 -103.691869039427 66.8003098208156 -1.55226628914699 0.121322405073649 SDAD1 essential 7.61387697472978e-07 1 0.592454356894163 4.01230859343633 -1.55226628914699 0.00101948997889038 82.2643623529895 90.4370906156677 0.909630791890353 0.363517526034942 -528.545213223174 184.021136781337 -2.8721983923576 0.0042742097707665 ZKSCAN8 other 1 1 1 0.909630791890353 -2.8721983923576 4.59878995928378e-07 113.386394328157 39.4222448967958 2.87620338783328 0.00422135479698998 -142.517340863052 65.9425037363063 -2.16123642245912 0.0312183297450365 FAM109A other 0.00285124977475595 1 1 2.87620338783328 -2.16123642245912 2.2247486087456e-34 -4.62116579814354 6.79045730895092 -0.680538230032327 0.496527449301419 -76.62850858723 9.41382998049567 -8.13999283458434 4.24295385806893e-15 ZNF813 other 2.04476644629808e-30 4.11990819618494e-11 1 -0.680538230032327 -8.13999283458434 0.00932000549121968 54.0681274084886 18.0467516603124 2.99600329334574 0.00289146149221258 64.8642732334786 27.5775420816896 2.35206868840374 0.019113197009069 HOXC4 other 1 1 1 2.99600329334574 2.35206868840374 0.20623236708885 81.9260529612092 46.027090540245 1.77995289295062 0.0757768633779908 78.7456991036144 67.2727953034334 1.17054299213274 0.242418993241081 PIM3 other 1 1 1 1.77995289295062 1.17054299213274 0.0779667309732209 113.317639122383 219.388864622307 0.516514998687227 0.605755444202565 -952.552227778419 506.343075003518 -1.88123877821732 0.0606024854748795 WWP2 other 1 1 1 0.516514998687227 -1.88123877821732 6.52479965092933e-06 98.4579860653078 21.7836432138207 4.51981264561112 7.98371608772162e-06 -17.2566309705113 39.0744391435287 -0.441634770677681 0.65897246621167 ZNF26 other 0.0369368908239109 1 0.0696100205688448 4.51981264561112 -0.441634770677681 3.92322292734181e-24 146.746692012373 328.584717290842 0.446602304642434 0.655382956950397 -2295.11348416515 395.742337929236 -5.79951464423689 1.27521061334786e-08 MGEA5 other 3.4547901098172e-20 0.000117574418550672 1 0.446602304642434 -5.79951464423689 0.813624734590396 -48.9330825911323 84.7866857543924 -0.57713168235966 0.564147694979323 -88.2016330867887 195.40216656051 -0.451385133744028 0.651935914761746 MT1F other 1 1 1 -0.57713168235966 -0.451385133744028 0.00310390814848048 168.892715231789 155.164992350893 1.0884717788008 0.27698680537875 -547.228111005988 263.318281477601 -2.07820022193384 0.0382740129424589 TXNRD1 essential 1 1 1 1.0884717788008 -2.07820022193384 0.0326506206229307 27.3811216429696 35.4121967946421 0.77321160846797 0.43982100453946 -148.743805604059 74.6297874856398 -1.99308896106236 0.046881730924758 NRARP other 1 1 1 0.77321160846797 -1.99308896106236 1.07757603985945e-31 94.6356273503403 16.0340156936393 5.90217879030033 7.2045056331806e-09 -0.320464593593237 20.1214151967578 -0.0159265434592729 0.987300262665311 ZNF583 other 9.81132984292032e-28 1 6.71964240406754e-05 5.90217879030033 -0.0159265434592729 5.73323119378212e-42 111.673640740082 16.5434123526897 6.75033894817507 4.71851945230408e-11 -33.9988363138317 21.6461958237269 -1.57066103396167 0.116986800225773 ZNF568 other 5.37949082912577e-38 1 4.5000520016624e-07 6.75033894817507 -1.57066103396167 2.7148574709204e-36 136.252992467909 22.8267684132999 5.96900051732778 4.97386445241936e-09 -23.0988094051461 28.7745152411695 -0.802752338711762 0.422558287780689 ZNF480 other 2.51070018910719e-32 1 4.65155803590259e-05 5.96900051732778 -0.802752338711762 4.18083950155601e-28 172.80950306795 37.2016136128549 4.64521525507797 4.50213962576785e-06 -46.6719951197451 46.4141099470236 -1.00555618050235 0.315185568530334 ZNF587 other 3.75773854399854e-24 1 0.0396188287067571 4.64521525507797 -1.00555618050235 0.444700558211332 107.957057392893 218.011245525015 0.495190315219339 0.620715823859847 323.150001221273 256.597820465969 1.25936378038773 0.208574283778194 TPM2 other 1 1 1 0.495190315219339 1.25936378038773 0.000799039730596679 -45.4727221239047 96.9048830821602 -0.469251091148326 0.639124198596088 -399.293677876117 134.644276549009 -2.96554512460674 0.00318700136675591 SH3BGRL2 other 1 1 1 -0.469251091148326 -2.96554512460674 4.74838420166529e-19 6.09227857930046 6.68727160779258 0.911026041203594 0.362786205480881 -48.6873517182649 9.93815565591277 -4.89903291958383 1.36093877255873e-06 ZNF808 other 4.0218814188105e-15 0.0119517643006107 1 0.911026041203594 -4.89903291958383 3.87891787444884e-67 218.814253155219 60.7888013352948 3.59958163919532 0.000355152732367867 -627.631837622151 78.0548592817158 -8.04090665716148 8.40065510856069e-15 YTHDF2 other 3.7792296850755e-63 8.14779538979301e-11 1 3.59958163919532 -8.04090665716148 0.00347692308897283 28.0109011182833 10.1862732354518 2.74986744129302 0.00620988998009984 -29.8622417108631 23.0465337438797 -1.29573679247073 0.195751722955407 NBR2 other 1 1 1 2.74986744129302 -1.29573679247073 5.15051676247591e-09 73.6286911277796 19.7718944366359 3.7239067487307 0.000221778165539483 -22.6982807718664 26.5381326898704 -0.855308134793161 0.392848201063546 TMA16 essential 3.56261244460459e-05 1 1 3.7239067487307 -0.855308134793161 0.000116708347939798 2172.58431372551 553.973145658242 3.92182243986575 0.000101984783338823 4045.34052287581 1291.21971598077 3.13296062072836 0.00184667208176022 HLA-DRB5 other 0.574056204639109 1 0.846983625628929 3.92182243986575 3.13296062072836 0.000293110164337592 -41.236811218833 147.599991690788 -0.279382205557445 0.780084005807685 -579.300080501205 194.344527676265 -2.98078925827122 0.00303597952735067 ATL1 other 1 1 1 -0.279382205557445 -2.98078925827122 0.000426502837801747 126.972134512558 33.1392523206703 3.83147251736153 0.000146044846698678 -21.0552178099893 123.386357962512 -0.170644617100915 0.864582191154969 MAFK other 1 1 1 3.83147251736153 -0.170644617100915 3.43957300707524e-19 15.4453627061989 11.8633836706532 1.30193569853149 0.193622637307263 -62.2078209657199 15.3070496034752 -4.06399813009011 5.71791280275258e-05 C1orf228 other 2.91813373920263e-15 0.462922220510849 1 1.30193569853149 -4.06399813009011 0.725836392843625 -40.468926948616 169.806167504281 -0.238324246659626 0.81174132783061 -146.255714785037 220.097471754985 -0.664504292661071 0.506718083401031 PLN other 1 1 1 -0.238324246659626 -0.664504292661071 2.8804796907692e-37 52.3667198912319 18.8821943006596 2.77333868391571 0.00578812691836464 -171.810687861637 28.2107495321929 -6.09025604461781 2.48962426678403e-09 ZNF28 other 2.6707807692812e-33 2.31908500450932e-05 1 2.77333868391571 -6.09025604461781 0.0317122527928645 30.5813719162021 32.9502608353436 0.928107126951768 0.353863164138158 -52.4193924248683 43.9389700044384 -1.19300457929654 0.233513418526759 ITGBL1 other 1 1 1 0.928107126951768 -1.19300457929654 8.24014289473198e-17 49.5699900062671 24.2752801379951 2.04199456090648 0.0417631257914635 -68.9080068431663 27.5382371377581 -2.50226644859142 0.0127112996074907 ZNF511 other 6.80965408820651e-13 1 1 2.04199456090648 -2.50226644859142 5.08358987014219e-12 35.1980679645636 10.4504677385755 3.36808541445834 0.000824270687553547 -17.5854592454963 12.3096407268059 -1.42859240458591 0.153839041424472 KCNRG other 3.85793635245091e-08 1 1 3.36808541445834 -1.42859240458591 0.0148800919531537 81.3612278327756 31.3576514441511 2.59462121956685 0.00978934374090214 46.0607862687844 39.0357476408125 1.1799642392561 0.238659308115241 WDHD1 essential 1 1 1 2.59462121956685 1.1799642392561 0.207382070974648 484.415620290143 329.005919263265 1.47236141335962 0.141641483796966 -363.282384012021 784.611104703616 -0.463009485634605 0.643587526360484 CTNND1 other 1 1 1 1.47236141335962 -0.463009485634605 8.87966002912445e-08 831.077054182018 297.265652517512 2.7957385831283 0.00540584651360138 -2359.241376719 653.039851983311 -3.6127065898871 0.000338141411392732 DDX39B other 0.000574957986885808 1 1 2.7957385831283 -3.6127065898871 0.0125329892867401 1134.70622712442 381.554184097545 2.97390586820122 0.0031031334773543 1143.8433983292 1212.93227925128 0.943039787048351 0.346181605938866 ARC other 1 1 1 2.97390586820122 0.943039787048351 0.121517788115959 -322.302748505081 198.163595282242 -1.62644782481883 0.104576916268983 -759.785922291041 417.801032870673 -1.81853528956265 0.0696683098707895 NUDT16 other 1 1 1 -1.62644782481883 -1.81853528956265 1.79946776292349e-07 41.3693328154831 70.2856942864916 0.588588235990918 0.556442313368523 -317.202798892472 93.1762029997804 -3.40433274463029 0.000724606848110145 LRBA other 0.00114338181656159 1 1 0.588588235990918 -3.40433274463029 0.350283405392275 -16.2839002263201 68.8837000491841 -0.2363970026972 0.813236149473476 46.3881375978449 87.8427351285222 0.528081662416074 0.597712557730157 ZNF536 other 1 1 1 -0.2363970026972 0.528081662416074 0.285240927608094 86.1610052032447 83.0409000570144 1.03757311329824 0.300041298196854 -124.770501818989 151.437912241884 -0.823905321804088 0.410441760521054 MMP17 other 1 1 1 1.03757311329824 -0.823905321804088 4.78793905107569e-08 203.431976913377 75.9528653475912 2.67839766126518 0.00767710200898349 -189.806043263167 101.716885346778 -1.86602295789998 0.062709375456083 BAZ1A other 0.000314567595655673 1 1 2.67839766126518 -1.86602295789998 2.45286238996325e-10 2.73248268178077 2.07497512521233 1.31687491024797 0.188570702597705 -21.4301383842787 4.39494771878639 -4.87608494014038 1.51757920114005e-06 AKR1C4 other 1.78258413439249e-06 0.0133046168563948 1 1.31687491024797 -4.87608494014038 6.74110512300465e-22 144.429327332445 84.6169916589769 1.70685963304538 0.0885568962658508 -793.265401827151 127.966452858102 -6.19901063215981 1.31373400723385e-09 COPS8 other 5.86139090445254e-18 1.22899816376727e-05 1 1.70685963304538 -6.19901063215981 0.124659849299824 -16.3599063249706 30.8899655003029 -0.529618795618602 0.596645210879444 -120.28037774647 60.1616509423501 -1.99928651994156 0.046196079671965 CCDC69 other 1 1 1 -0.529618795618602 -1.99928651994156 0.968792138968658 -28.5861306166389 113.956487539041 -0.250851278711495 0.802047267005346 -23.8987045128043 223.077482134549 -0.107131855192762 0.914733653472936 RYR2 other 1 1 1 -0.250851278711495 -0.107131855192762 2.7414962598218e-06 0.307138585284161 2.85651338275298 0.107522193713006 0.914424521164563 9.10499261092275 3.60080701658759 2.52859777515968 0.0118061924508552 ZNF534 other 0.0160624265862959 1 1 0.107522193713006 2.52859777515968 2.29815380648004e-12 404.661047234305 76.9060081573384 5.26176116703948 2.30226228022137e-07 -40.3514022684895 90.9099813047462 -0.443861077621658 0.65737661276441 KLHL9 other 1.75693858505399e-08 1 0.00209321686517727 5.26176116703948 -0.443861077621658 0.405711467893374 -4.90555235769076 3.88366546679182 -1.26312433437865 0.207216471591171 -7.91712689992064 9.26885650872351 -0.854164361317853 0.393480846405901 TAT other 1 1 1 -1.26312433437865 -0.854164361317853 1.49314787223532e-08 207.263898901656 173.733615632506 1.1929982470409 0.233515895902448 -2080.62128408465 407.887293715522 -5.10097106760026 5.04211725575325e-07 C6orf89 other 0.000101115973907776 0.00449202226315057 1 1.1929982470409 -5.10097106760026 0.019475551777433 -25.4147699829487 81.7304276408472 -0.31095848531015 0.755981477389765 -339.579917002636 134.86218408046 -2.51797729154408 0.0121619485774172 FAM19A2 other 1 1 1 -0.31095848531015 -2.51797729154408 0.00239472527305055 60.9400588379499 32.7676510796416 1.85976280966357 0.0636264541938334 -33.1207403775436 36.9758200611715 -0.895740522394088 0.370910621377716 TUSC1 other 1 1 1 1.85976280966357 -0.895740522394088 0.0543009331906913 -76.01549901582 59.9154163158469 -1.26871352466451 0.20522174229313 -160.892629583729 72.5795229091097 -2.21677717260849 0.0271547750456219 PAPSS2 other 1 1 1 -1.26871352466451 -2.21677717260849 1.06658925326228e-08 -59.9810366624543 73.8243572563381 -0.812483019041859 0.416956908634608 -651.300080450525 119.756447098439 -5.43853876956755 8.95730535041119e-08 FAN1 other 7.26987235023573e-05 0.000814039910245369 1 -0.812483019041859 -5.43853876956755 0.693097674900695 -87.7037922993198 332.49304259441 -0.263776323302815 0.792076618768264 -283.380562854961 429.165479179083 -0.660306051169394 0.5094053374617 ABCA4 other 1 1 1 -0.263776323302815 -0.660306051169394 1.02081379211076e-05 62.2813237263276 50.5100300995982 1.23304863615243 0.21822201141082 -250.072166643735 81.4542540857287 -3.07009338493899 0.00227363615331523 CEP290 other 0.0566653736000683 1 1 1.23304863615243 -3.07009338493899 1.00923268081827e-11 3.39533325978342 4.66312100091536 0.728124631361042 0.466926371101607 -19.6874007295448 5.98790170472058 -3.28786304458275 0.00109085012115392 SSBP3-AS1 other 7.60759594800814e-08 1 1 0.728124631361042 -3.28786304458275 7.94264948779185e-08 -35.0551037006926 52.9002932987048 -0.662663692670885 0.50789935419547 -319.679727531518 70.6542215453018 -4.52456655157607 7.83220939034872e-06 TOGARAM1 other 0.000515716231242325 0.0666677663306483 1 -0.662663692670885 -4.52456655157607 6.67879794377437e-05 -0.681618578873933 369.142161140859 -0.00184649343972887 0.998527558705046 -1314.88140638354 476.740961985268 -2.75806257743837 0.00605953430187646 DLL1 other 0.338347903831609 1 1 -0.00184649343972887 -2.75806257743837 0.00142870899426559 231.777076029009 85.9199107566368 2.69759446894101 0.00725512287512236 -302.643180763012 181.947196940003 -1.66335720391893 0.0969595361030468 ANKRD13B other 1 1 1 2.69759446894101 -1.66335720391893 0.000157107603069258 342.977487746494 115.654896851012 2.96552499794558 0.00318759070216726 -210.67834439583 199.558015870423 -1.05572478999103 0.291678600762325 ECI2 other 0.760400798855207 1 1 2.96552499794558 -1.05572478999103 0.00149647089110911 116.140982766956 99.2261580647442 1.17046739521221 0.242453751712666 -259.989280100544 115.798100226723 -2.24519469310382 0.0252572243116472 UNC13B other 1 1 1 1.17046739521221 -2.24519469310382 3.12218104649575e-36 -28.1317604085148 97.1235417060797 -0.289649243781169 0.772221651578851 -947.787791817315 116.974087473188 -8.10254486519984 5.41286071074014e-15 LDB1 other 2.88708081369462e-32 5.25264003370223e-11 1 -0.289649243781169 -8.10254486519984 3.17154151329101e-06 -18.8981753837652 47.3347140603661 -0.399245580308444 0.689907297813172 -206.718770107544 60.4816537157102 -3.41787562686714 0.00069025390032514 PPP1R14C other 0.0184710577734069 1 1 -0.399245580308444 -3.41787562686714 2.24903104986554e-17 200.169548696884 64.2784094998905 3.11410239074483 0.00196610626948246 -290.67595265732 77.9551545741452 -3.72875859518501 0.000217681552771171 CTR9 essential 1.86894480243827e-13 1 1 3.11410239074483 -3.72875859518501 1.34029314355007e-09 -2886.90925252974 3480.58030663974 -0.829433312319363 0.407312091009042 -16353.482879609 3968.94238346778 -4.1203628824968 4.5261348229805e-05 SMOC1 other 9.49329633576515e-06 0.369558908296358 1 -0.829433312319363 -4.1203628824968 2.86626547909337e-16 -71.532883518901 118.36333503818 -0.604350016800618 0.54592458725927 -821.850427478261 143.733868919426 -5.7178620018847 2.00172193266807e-08 LRRTM3 other 2.35033769285656e-12 0.000184058331708829 1 -0.604350016800618 -5.7178620018847 6.25367608851686e-05 205.098766704899 58.7928434346809 3.48849884991129 0.000534878041150769 -305.82567625037 139.911021361684 -2.18585836393675 0.0293547509944744 ZNF652 other 0.317999429101083 1 1 3.48849884991129 -2.18585836393675 0.0156787087006429 40.4389293949023 117.997381908043 0.342710395273151 0.731981124936814 641.640965378485 233.171963005069 2.7517929561906 0.00617355642196439 SLC5A3 other 1 1 1 0.342710395273151 2.7517929561906 4.89590807496392e-50 129.418110733431 20.203933714968 6.40558975094797 3.8938033317136e-10 -80.3796509518878 25.8485688026543 -3.10963641993339 0.0019962714683993 GPATCH3 other 4.67265466674556e-46 1 3.6858742338001e-06 6.40558975094797 -3.10963641993339 2.98341537150373e-34 -177.092670598143 274.768279220997 -0.644516430718358 0.519581110013468 -2817.70864925582 320.695256949271 -8.78624983749459 3.62574837254676e-17 CDC42BPB other 2.74086370180047e-30 3.5430813096527e-13 1 -0.644516430718358 -8.78624983749459 0.00181620479070652 537.063780161985 396.857724834825 1.35329047805612 0.176660863367079 -2371.46731125342 931.732312043641 -2.54522385947086 0.0112626537551275 RPL10A essential 1 1 1 1.35329047805612 -2.54522385947086 0.827812320317201 4.77758212033188 70.0554530933899 0.068197148250015 0.945659889189798 -51.2403015654076 112.967442689606 -0.453584681970696 0.650352938371037 RASSF9 other 1 1 1 0.068197148250015 -0.453584681970696 3.42969501828902e-06 68.5094544112904 20.9269521888756 3.2737425781337 0.00114545855425041 -131.442274285539 45.0849033140812 -2.91543875274289 0.00373414656798454 ZNF830 essential 0.0199299577512775 1 1 3.2737425781337 -2.91543875274289 0.247799519766293 -114.875604203697 90.5011627227122 -1.26932738483887 0.204998367490053 -294.504012432306 198.633340660414 -1.4826514594838 0.138886166160901 GRIN3A other 1 1 1 -1.26932738483887 -1.4826514594838 3.68359835729462e-05 230.34345013977 112.635273256655 2.04503832129834 0.0414495507400473 -347.851025484538 176.297636337511 -1.97308955871989 0.0491151009060959 TMEM184B other 0.192689030070082 1 1 2.04503832129834 -1.97308955871989 3.01583869334616e-49 199.098551841385 112.536174288043 1.76919602164349 0.0775569944667953 -1072.02355005041 143.797185722196 -7.45510800274954 4.84740323625273e-13 MTOR essential 2.87530061023623e-45 4.66611035521688e-09 1 1.76919602164349 -7.45510800274954 0.041965750882632 -742.080401209989 614.473011482746 -1.20766964104627 0.227830554459895 -2677.82201802868 1066.17389303884 -2.5116184475276 0.012379161186388 SCAMP5 other 1 1 1 -1.20766964104627 -2.5116184475276 6.33299144427158e-06 169.024461216482 125.445216220389 1.34739662706253 0.178560419464849 -626.297842056716 209.946651760621 -2.98312850814508 0.00301522218330666 ZNF521 other 0.0358953955061313 1 1 1.34739662706253 -2.98312850814508 0.644840061433464 9.42097913101634 10.362263682321 0.90916226606831 0.363764473289302 12.609291713381 16.5541468930705 0.761699880690269 0.446649078264262 ALPK2 other 1 1 1 0.90916226606831 0.761699880690269 7.45770595356864e-42 84.7866948257648 43.8325835251996 1.93433030879917 0.0537162566123117 -368.1808635457 56.2853079646289 -6.54133159895073 1.70402392949173e-10 LRIG2 other 6.99458241385203e-38 1.60910979661904e-06 1 1.93433030879917 -6.54133159895073 0.61123374737198 -62.2266604969326 82.9351257609746 -0.750305252761955 0.45347465550176 -5.09109426532269 115.280455002959 -0.044162683649991 0.964794899291196 PNP other 1 1 1 -0.750305252761955 -0.044162683649991 1.91908338815986e-12 33.5156174216706 4.69921289683959 7.13217684693775 4.13740398811717e-12 20.1248544960715 6.29323590703866 3.19785477508683 0.00148540899750499 PAX9 other 1.46905833363637e-08 1 3.9723215689913e-08 7.13217684693775 3.19785477508683 4.84987543038939e-64 149.41346425482 66.8964586841279 2.23350334522671 0.0260200039716936 -769.441768773612 85.9065974633177 -8.95672499544829 9.64989884770019e-18 FOXJ3 other 4.71165398062329e-60 9.44435600224417e-14 1 2.23350334522671 -8.95672499544829 2.48020832068961e-25 39.0680336661481 54.5031133727561 0.716803706220508 0.473877268566851 -441.907335588743 69.6344888541201 -6.34609864825046 5.52033271446912e-10 SFT2D1 other 2.19870467629134e-21 5.18745665178663e-06 1 0.716803706220508 -6.34609864825046 3.61421026536101e-13 233.002527455994 54.1010554647588 4.30680188130101 2.06211440348041e-05 -176.834090567175 76.5104463769617 -2.31124113034088 0.0213005911204806 CHAMP1 other 2.81149416542433e-09 1 0.176723204378271 4.30680188130101 -2.31124113034088 1.23730336491429e-06 -229.876938182159 270.814844944855 -0.8488343326562 0.396438215289044 -1080.58821129923 314.63439000141 -3.43442498861739 0.000650496548119813 INPP5F other 0.00743743052649979 1 1 -0.8488343326562 -3.43442498861739 0.0348416980749972 148.788874841975 57.5977864557624 2.58323946105553 0.010111623963661 119.037705889828 93.4340172136682 1.27402962475228 0.203330051047368 ARHGAP11A other 1 1 1 2.58323946105553 1.27402962475228 0.541005409747901 -3.70382558617911 4.10936645456221 -0.901313043539141 0.36791836346969 -8.49045660222181 8.97499180936077 -0.946012741021825 0.344664866910604 SUCNR1 other 1 1 1 -0.901313043539141 -0.946012741021825 9.30161590414762e-44 1291.35549321674 217.670606145842 5.93261311704862 6.06132164415953e-09 -786.376470752121 279.475811278054 -2.81375503359661 0.00511712279986307 HMGN2 essential 8.76584282806871e-40 1 5.66066828348058e-05 5.93261311704862 -2.81375503359661 0.0581584041657448 11.9583151434215 68.7878702857945 0.173843369386754 0.862069244355066 219.703875735085 108.632819333878 2.02244475548255 0.0437404422117501 SELENOM other 1 1 1 0.173843369386754 2.02244475548255 1.4127167304016e-12 109.74282985976 103.766752007116 1.05759145137581 0.290824671727771 -666.403992849291 146.638620969816 -4.54453259613278 7.13121924830016e-06 UBE2J1 other 1.08411881891019e-08 0.0608079065302555 1 1.05759145137581 -4.54453259613278 1.32332358790683e-07 203.326564604518 115.26147085395 1.76404624284343 0.0784244380888685 -785.672350685268 210.914278353315 -3.72507900754421 0.000220903754093018 OPA1 essential 0.00084639776682521 1 1 1.76404624284343 -3.72507900754421 0.872169807297411 -75.9999999999984 145.637621063754 -0.521843184782103 0.602043305242766 -66.499999999999 230.769755345351 -0.288166011618292 0.773355974901429 RYR3 other 1 1 1 -0.521843184782103 -0.288166011618292 5.09642692883639e-32 26.7644338073249 9.72625850107111 2.75177076615612 0.00617396747517416 -56.3039276239135 12.4940651854765 -4.50645380731351 8.4742776169117e-06 KTI12 essential 4.64794135909879e-28 0.0720398340213664 1 2.75177076615612 -4.50645380731351 1.46064692180235e-06 -94.6040365556637 124.204336453886 -0.761680624498867 0.446662441294177 -1367.17922162475 268.512990461016 -5.09166882122692 5.29064012191134e-07 SELENOT other 0.00873174729853446 0.00470972783652548 1 -0.761680624498867 -5.09166882122692 0.000416906237246483 -5.59636051010166 13.7473824515339 -0.407085532815538 0.684144033299417 -42.2111752697798 10.7165634795705 -3.93887232136022 9.52341320804506e-05 ARHGEF15 other 1 0.759301735077432 1 -0.407085532815538 -3.93887232136022 0.0872554965538142 27.6340188614932 12.9394365468132 2.13564313728166 0.0332637925319542 3.77724122258852 29.6017570461467 0.127601926355254 0.898522702593264 CES1 other 1 1 1 2.13564313728166 0.127601926355254 0.0247594572690365 369.471896670965 167.94638107174 2.19993961354333 0.0283375778436438 -42.9442597502919 196.229305068234 -0.218847331367551 0.826871852512018 RUSC2 other 1 1 1 2.19993961354333 -0.218847331367551 0.000389748572398753 4.92550933024235 31.7496642363814 0.15513579273063 0.876785893806039 -168.496195086432 53.1117188286616 -3.17248620083265 0.00161799358170553 FICD other 1 1 1 0.15513579273063 -3.17248620083265 4.26598333907371e-06 141.925886990801 42.8729376225138 3.31038400588328 0.00100873051007819 -48.0402102496721 60.2677190201269 -0.797113463571246 0.425817020669974 OSTC essential 0.0246061918997772 1 1 3.31038400588328 -0.797113463571246 0.000105863691969108 140.282387258948 61.8935294117664 2.26651135574568 0.0239150102001291 -272.970792376376 122.513916571861 -2.22807987871536 0.026390497720622 LTN1 other 0.523390093095269 1 1 2.26651135574568 -2.22807987871536 0.0170841415253672 35.5439516129018 26.1266581791048 1.36044768409489 0.174389590908394 -126.781451612905 59.1114190268084 -2.14478782103685 0.0325205504093754 RUNDC1 other 1 1 1 1.36044768409489 -2.14478782103685 0.934238326543883 -69.8407601959574 551.781632927933 -0.126573187703548 0.899337244953269 313.351088945272 1257.25661287512 0.24923399545992 0.803298514715164 CCDC152 other 1 1 1 -0.126573187703548 0.24923399545992 1.01651454559809e-08 17.4671482611584 3.7415598762203 4.66841339949466 4.04154886826685e-06 -13.7125833806584 7.71996712636592 -1.77624893425077 0.0763860088210971 STKLD1 other 6.93669525916139e-05 1 0.0356262532737723 4.66841339949466 -1.77624893425077 0.000268516893735725 49.9825403526093 39.2451252347807 1.27359869674496 0.203482667167277 -42.18901692841 45.5952333088998 -0.925294463186245 0.355323435053302 GRK5 other 1 1 1 1.27359869674496 -0.925294463186245 5.57962721630303e-08 332.660099364307 95.0211071660239 3.50090742242219 0.000511456662034573 -199.678195657462 110.677297101717 -1.80414774200665 0.071898154660198 DCAF12 other 0.000364684434857566 1 1 3.50090742242219 -1.80414774200665 0.00270718853686507 115.722339569859 47.8275791916885 2.41957342448914 0.0159468796682763 -68.7420596915412 98.7483599535253 -0.696133684892527 0.486716031038646 SFMBT2 other 1 1 1 2.41957342448914 -0.696133684892527 0.0027903705616418 201.587952996943 63.0959142565185 3.19494463900437 0.00149988099803294 17.3350004937322 136.34651753147 0.12713929778024 0.898888628556769 SMC5 essential 1 1 1 3.19494463900437 0.12713929778024 1.602254732845e-29 56.8784036848793 29.2821165534129 1.94242802022622 0.0527258986824072 -187.531164176866 37.7799532798352 -4.96377438023354 9.91914947458066e-07 PRMT6 other 1.4471564747056e-25 0.00874373026184285 1 1.94242802022622 -4.96377438023354 1.05927759343863e-14 -100.772030142528 147.953989154471 -0.681103839906052 0.496165712376274 -860.301529520205 170.602771795009 -5.04271718723255 6.73276263386188e-07 CIPC other 8.46998363713528e-11 0.00597263373249887 1 -0.681103839906052 -5.04271718723255 0.000471515832342947 475.5364585361 123.53619839434 3.84936937283871 0.000136101638779544 298.535757784742 239.369548781873 1.24717517037551 0.213001258516837 PRC1 essential 1 1 1 3.84936937283871 1.24717517037551 6.25985107898956e-14 260.025142216875 473.161842005031 0.549547996336759 0.582910157386627 -4153.0050102199 714.654835454319 -5.81120396055216 1.19693406190629e-08 SREBF2 other 4.94465636729386e-10 0.000110417167210856 1 0.549547996336759 -5.81120396055216 5.8378967623129e-59 82.5657684500318 18.4154953040925 4.48349431207984 9.38959146648973e-06 -142.061922932838 23.5330627952284 -6.03669501794058 3.356502015073e-09 C1orf174 other 5.64232722077542e-55 3.12154687401789e-05 0.0816331082096617 4.48349431207984 -6.03669501794058 0.86362312952886 -31.0662882700275 57.6246128741402 -0.539114914973579 0.590082739629784 -33.7757043293323 74.0591631883457 -0.456063812703833 0.648571166765568 RASGEF1A other 1 1 1 -0.539114914973579 -0.456063812703833 8.65308436355884e-13 603.028471645353 87.6012526454292 6.88378822716318 2.0390139799904e-11 -136.48669724234 193.624098737137 -0.704905526391283 0.481245410449343 SPOUT1 other 6.67152804430386e-09 1 1.94848175927882e-07 6.88378822716318 -0.704905526391283 4.66064608723649e-05 -36.5866228070181 97.5401682209956 -0.375092881981957 0.707772951991742 -793.030701754392 190.623975582309 -4.16018341518626 3.82837362993031e-05 DZIP3 other 0.240675763944892 0.314003205126884 1 -0.375092881981957 -4.16018341518626 0.0411972879347835 41.4783312944594 22.420289908147 1.85003545736432 0.0649817557118944 27.919328530651 16.7591976726439 1.66591080766497 0.0964461553590929 KIAA0753 other 1 1 1 1.85003545736432 1.66591080766497 9.6768232833246e-13 76.9976740179197 36.0262266033607 2.13726724326819 0.033130736485664 -76.4309958649203 41.2076498635493 -1.85477687075108 0.0643014432551798 DCLRE1A other 7.45405697514494e-09 1 1 2.13726724326819 -1.85477687075108 0.00251076143656605 226.006780711114 66.0956934968194 3.41938738750036 0.000686391944971564 109.880987620328 140.441559508243 0.78239652140774 0.434404349496829 APRT other 1 1 1 3.41938738750036 0.78239652140774 0.0667769043924153 34.61332684825 82.1149342106217 0.421522920050914 0.673580540504329 -403.039971701453 185.430457600199 -2.17353706029479 0.0302761885303026 TBKBP1 other 1 1 1 0.421522920050914 -2.17353706029479 3.61203223073167e-16 441.423561341756 52.2620076936662 8.44635674789153 4.46556892012998e-16 120.828343440341 122.699391276128 0.98475096073153 0.325290064090123 CCDC167 other 2.95861560019231e-12 1 4.33785364901426e-12 8.44635674789153 0.98475096073153 0.0207605403523098 11.381136057011 10.9967159289882 1.0349577210601 0.301261032506058 -38.0236274950696 21.0898216801801 -1.80293736342037 0.0720868098414074 ZFP2 other 1 1 1 1.0349577210601 -1.80293736342037 0.309450119996265 26.8523268333529 20.4770268915036 1.31133913998495 0.190431786703783 14.2368225864333 26.3446698510032 0.540406187170007 0.589192250030176 L3MBTL3 other 1 1 1 1.31133913998495 0.540406187170007 1.78565076600471e-07 119.968779654997 132.780698153815 0.903510685837966 0.36675383448784 -572.790963071453 179.879942764045 -3.18429589352719 0.00155509661601948 MFAP3L other 0.00113478106179599 1 1 0.903510685837966 -3.18429589352719 0.192076714099163 -4.96910877435282 78.3361364816314 -0.0634331612144033 0.949450585742988 159.809555002828 118.317441850715 1.35068467085745 0.177495447048844 NAGA other 1 1 1 -0.0634331612144033 1.35068467085745 2.4690981252215e-57 53.5384832252659 71.6745308494602 0.746966636415299 0.45548448044214 -923.733597063165 87.0265423904177 -10.6143892620612 1.41311088276935e-23 KIF1BP other 2.38267969083874e-53 1.38965324211538e-19 1 0.746966636415299 -10.6143892620612 0.41675138345175 7.21921936479471 118.266868730102 0.0610417730875228 0.951353911541039 -288.735780864125 246.712025776545 -1.1703352520223 0.242505379125092 RORB other 1 1 1 0.0610417730875228 -1.1703352520223 7.60147298337624e-24 38.5384828622224 74.2097498308182 0.519318323402 0.603804117827364 -587.253717729752 94.2729972323316 -6.22928871437588 1.11074266820722e-09 SGMS1 other 6.68625563617774e-20 1.0398772859756e-05 1 0.519318323402 -6.22928871437588 2.11068095053837e-07 4.83049147442328 1.39692640340006 3.45794271098755 0.000597537822945389 4.69218043741616 1.08895279018403 4.30889243290631 2.02764881151684e-05 SNORD118 other 0.00133542783740563 0.168842316535007 1 3.45794271098755 4.30889243290631 0.840436958497772 -27.4871895649617 139.745850742201 -0.196694137385654 0.844158760564666 -183.821515717246 313.463821629668 -0.586420195994472 0.55789734851938 RN7SK other 1 1 1 -0.196694137385654 -0.586420195994472 0.765288382118639 -7.97301604451396 10.9584171420484 -0.727570044210201 0.467266442174245 -5.17970095858911 20.5645559517932 -0.251875166705821 0.801255965630824 RNU4-2 other 1 1 1 -0.727570044210201 -0.251875166705821 9.52898400260748e-21 9.33566925533161 7.3125242244581 1.27666848939888 0.202403562130041 -45.89010744199 10.1319152522123 -4.52926285896145 7.66343013684869e-06 ZNF525 other 8.20159653104426e-17 0.0652617710454035 1 1.27666848939888 -4.52926285896145 0.00433481911154725 -379.145612911503 336.083499228635 -1.12812921128738 0.259910901816945 -1122.84882065546 394.526096510575 -2.84606983058056 0.00464360782246244 INF2 other 1 1 1 -1.12812921128738 -2.84606983058056 0.0425459154361154 94.4894973581732 125.957384796661 0.750170365244656 0.453554875132726 -317.28814842137 209.026023735403 -1.51793610552058 0.129751935249261 GP1BB other 1 1 1 0.750170365244656 -1.51793610552058 4.39560400016111e-06 171.334776009837 40.9746730152783 4.18148000707538 3.50225808867855e-05 -111.47636697727 83.2465265797124 -1.33911133061541 0.18123213002798 EFCAB2 other 0.0253362614569286 1 0.297166598824375 4.18148000707538 -1.33911133061541 0.000933049871307694 352.720584461726 159.187738619149 2.2157522150974 0.0272254629063562 -758.328885555249 333.569076984059 -2.27337885277504 0.0234900809329757 COX20 other 1 1 1 2.2157522150974 -2.27337885277504 0.484603041810958 42.2367454897159 43.8541256658541 0.963119087393013 0.336022843853259 -38.044017212112 91.8938879790217 -0.41399942965518 0.679078572357746 CHML other 1 1 1 0.963119087393013 -0.41399942965518 0.000169872325948774 3.79486578466945 2.78642411876727 1.36191248098596 0.173927137488585 -4.70641889607607 3.54884043676416 -1.32618498350053 0.185471138312004 RAET1G other 0.81759550479145 1 1 1.36191248098596 -1.32618498350053 0.00173529432276581 33.9592102594171 41.0850785221721 0.826558241603228 0.408938557775828 -76.2788275597806 52.3267032556478 -1.45774189493865 0.145629943837666 SAMD5 other 1 1 1 0.826558241603228 -1.45774189493865 0.0499456381875103 -0.303473741794386 8.33173127847967 -0.0364238513762727 0.970960990301095 -15.9342177242888 10.5774573226823 -1.5064317669351 0.132677213818229 ECT2L other 1 1 1 -0.0364238513762727 -1.5064317669351 3.16305339435274e-05 44.7696959105212 10.9355931327843 4.09394308721164 5.05278292229067e-05 26.5038298297303 14.1743756192266 1.86984108095594 0.0621743069272813 CENPW essential 0.167009219221825 1 0.425848544690657 4.09394308721164 1.86984108095594 5.90465170071393e-15 -1.35848724364526 77.092518832569 -0.0176215184588228 0.985949020767249 -361.559166598032 87.4802201927859 -4.13303905501427 4.31022745540698e-05 SPRN other 4.73966392016308e-11 0.352361094479521 1 -0.0176215184588228 -4.13303905501427 1.11243025727889e-14 62.1009404743926 59.0826555675928 1.05108580306359 0.293798739481765 -382.958868409123 80.6080183907187 -4.75087808948318 2.75001690328786e-06 FAM229B other 8.89276747668746e-11 0.0238508966022156 1 1.05108580306359 -4.75087808948318 0.256259812215686 -1.77970817164251 14.7055516104556 -0.12102287753539 0.903728667853412 12.7605506676278 17.0768054207079 0.747244601859428 0.455318716823704 FANK1 other 1 1 1 -0.12102287753539 0.747244601859428 9.13664658067698e-44 67.8877828075614 28.1319932115654 2.41318779999037 0.0162242407030675 -196.359650278572 32.6632118274515 -6.01164549634225 3.87875298464076e-09 EEF1AKMT2 other 8.61128940228806e-40 3.60452514862666e-05 1 2.41318779999037 -6.01164549634225 0.0167463947816082 -28.5751780619029 18.5501921107559 -1.54042491265275 0.124178927153053 -70.5677264465794 25.4401233608905 -2.77387516740836 0.00577599955991462 DDO other 1 1 1 -1.54042491265275 -2.77387516740836 3.77567425410104e-12 79.5479132377407 73.7878262043461 1.07806283678073 0.281600431434473 -249.405466041201 85.7271605331012 -2.90929344317779 0.0038073295444618 PLPP4 other 2.87479837707253e-08 1 1 1.07806283678073 -2.90929344317779 0.000739760660532712 -82.0470610586932 114.199180658377 -0.718455776877543 0.472859375618223 -381.781997077917 145.949080284862 -2.61585750545847 0.00920778554081867 ATP1A1-AS1 other 1 1 1 -0.718455776877543 -2.61585750545847 2.50280105773567e-08 2.8191544128672 7.35388946811555 0.383355559679035 0.70164257100993 31.156182212581 8.76090840301123 3.5562730232258 0.000417253192677826 RBM20 other 0.00016721213866732 1 1 0.383355559679035 3.5562730232258 3.3838428884219e-07 705.373201994809 188.609399541682 3.73986240192087 0.000208689767156572 -31.1071590487578 260.215925515856 -0.11954364048661 0.904899729945294 SNHG5 other 0.00211456342097484 1 1 3.73986240192087 -0.11954364048661 7.15751911232661e-09 -7.4872851667158 19.6838496617216 -0.380377075388664 0.703850769710253 -124.408399620823 27.1569241505797 -4.58109316544847 6.04601056664103e-06 RIPPLY2 other 4.92151014163578e-05 0.0517161903024646 1 -0.380377075388664 -4.58109316544847 1.29652704016091e-18 -7.28638344989939 7.81287955816595 -0.932611772094161 0.351535424268813 -55.69814848557 9.32121554541571 -5.97541685568713 4.76571138156115e-09 CYP17A1-AS1 other 1.09362055837573e-14 4.42162701981243e-05 1 -0.932611772094161 -5.97541685568713 5.2295398796123e-16 33.2390326568526 10.3188962819029 3.22118100122264 0.00137179289214181 -21.988021734401 13.3142332428255 -1.65146736829546 0.0993599030776425 SAMD13 other 4.27201112765529e-12 1 1 3.22118100122264 -1.65146736829546 1.82306172036336e-41 53.6492143296189 14.6331615458729 3.66627636559852 0.000276329763708746 -91.2699359590643 18.7904051704393 -4.85726279615559 1.65975396109795e-06 EFCAB7 other 1.70857344432454e-37 0.0145294861754515 1 3.66627636559852 -4.85726279615559 1.33488201162423e-09 134.010576001335 23.4161753784458 5.72299164297723 1.96510270229528e-08 -31.2349591547536 49.3495369033185 -0.632933176575629 0.527113728132395 ARRDC1-AS1 other 9.45645165507401e-06 1 0.000181988161259566 5.72299164297723 -0.632933176575629 4.08866331578349e-18 -8.52569859712087 7.47368648933343 -1.14076214051645 0.254593698754042 -57.3241854437139 9.02171656555609 -6.35402198984739 5.27651484364059e-10 LRIT2 other 3.42548212596341e-14 4.96045160450652e-06 1 -1.14076214051645 -6.35402198984739 0.553258414809571 -11.8653611224227 13.218645989652 -0.897623034288931 0.369879684695859 -29.5529868335001 32.9071500149945 -0.898071902915748 0.369640615231899 LRRC73 other 1 1 1 -0.897623034288931 -0.898071902915748 0.0401344859174571 -7.03829207820868 22.141087479148 -0.317883757283249 0.750724610906415 -46.1125811313731 28.4329772739161 -1.62179924694963 0.10556591333271 FOXO6 other 1 1 1 -0.317883757283249 -1.62179924694963 2.88468082798788e-73 79.416956926035 22.5820110579532 3.51682393220974 0.000482330920338034 -257.039581220963 28.9975024202447 -8.86419725036421 1.95590520996675e-17 INPP5B other 2.82237172210335e-69 1.91248411430549e-13 1 3.51682393220974 -8.86419725036421 0.00731008637135355 -126.686226065459 376.10381382264 -0.336838451005979 0.736400389592035 -1342.97303819468 553.398989983018 -2.42677175510547 0.0156372802641676 NEU4 other 1 1 1 -0.336838451005979 -2.42677175510547 2.73877949909934e-09 -33.2317073170725 27.1124858058059 -1.22569754596077 0.220972648381898 -220.377406931964 41.0063223306549 -5.37422998226831 1.2538453125732e-07 TRAF3IP1 other 1.91769340526936e-05 0.00113548231506629 1 -1.22569754596077 -5.37422998226831 5.20418275259955e-13 -23.1005960345419 119.906028179889 -0.192655835450451 0.847318424465867 -1073.03809755504 184.946465589109 -5.80188485428525 1.26398129617472e-08 GIGYF2 other 4.03220079671413e-09 0.000116564355133232 1 -0.192655835450451 -5.80188485428525 0.0237396510924689 195.403402187125 206.444543196893 0.946517641789941 0.344407700299602 -521.53479601913 356.568914324268 -1.46264796247729 0.14428253344878 C2orf72 other 1 1 1 0.946517641789941 -1.46264796247729 6.19346580065282e-28 55.7296306738125 62.8039443433672 0.887358767932196 0.375372762990532 -490.25599545334 76.2559595424912 -6.42908434166592 3.36092237176097e-10 RUFY2 other 5.56420967530649e-24 3.16598887419884e-06 1 0.887358767932196 -6.42908434166592 0.00763796100269593 -106.035985488848 158.285245250253 -0.66990442047332 0.503271731593347 -1000.26297978368 324.509069501866 -3.08238836381097 0.00218311447988812 GGTA1P other 1 1 1 -0.66990442047332 -3.08238836381097 1.06311922150988e-80 245.910305450664 50.6999951734614 4.85030234439519 1.71724313022956e-06 -553.38692289336 65.1277204416075 -8.49694905857357 3.09215821517241e-16 PHACTR4 other 1.04451463513346e-76 3.01361739650703e-12 0.0153057880197361 4.85030234439519 -8.49694905857357 1.41266723092345e-26 14.755711200887 13.9163097320234 1.0603178202431 0.289585707033084 -118.206762603685 18.1749238526464 -6.50383812125149 2.14482480056629e-10 TIMM23B other 1.2603817034299e-22 2.02342771685423e-06 1 1.0603178202431 -6.50383812125149 7.59216649510638e-49 85.3241794413627 26.4178009879612 3.22979870581376 0.00133270708621066 -207.749553277531 33.7984847943868 -6.14671203580208 1.79062894778809e-09 ZDHHC18 other 7.23153858658882e-45 1.67083587118107e-05 1 3.22979870581376 -6.14671203580208 0.820789811835683 -5.59392597867396 21.8818574303856 -0.255642191092339 0.798347419395644 -15.9324739312673 28.5086800843245 -0.558863962980447 0.576540827002506 C10orf128 other 1 1 1 -0.255642191092339 -0.558863962980447 8.93678826444119e-09 34.7397216459997 28.0403375241287 1.23891952499167 0.216038806062206 -104.074322163228 36.5273831422224 -2.84921374624637 0.0045893614566695 AGAP9 other 6.11633788818355e-05 1 1 1.23891952499167 -2.84921374624637 0.00938232353824712 0.265247390247367 1.8369681309594 0.1443941164667 0.88525567712231 -10.5188938938939 3.79984894348007 -2.76824001436758 0.0058750493697304 LRRC37A5P other 1 1 1 0.1443941164667 -2.76824001436758 1.13751674681858e-12 45.0632982808068 45.5711762965278 0.988855279652729 0.323279897657044 -188.074814420118 58.5106169908584 -3.21437072607699 0.00140397349106698 TMEM57 other 8.74977881652849e-09 1 1 0.988855279652729 -3.21437072607699 0.543763147305825 -2.39816293147682 8.61329241555901 -0.278425811614707 0.780816901851744 -9.94453546526582 11.2203011789138 -0.886298443035956 0.375943079594749 PTPN20 other 1 1 1 -0.278425811614707 -0.886298443035956 1.53281373368143e-10 325.672608504672 69.5377409557065 4.68339356482857 3.77252575058568e-06 -472.771672594334 163.26221155958 -2.89578138185273 0.00397187876807822 DAXX other 1.1215598089347e-06 1 0.0332849946974175 4.68339356482857 -2.89578138185273 4.19764574147431e-05 21.9158419492869 32.0664448915838 0.683450941424409 0.494684142250232 -74.1727267880225 40.9906960127017 -1.80950152115101 0.0710600681658112 TCEA3 other 0.218319555014079 1 1 0.683450941424409 -1.80950152115101 1.75923091758434e-11 423.045616864426 94.125398776544 4.49448950403649 8.94256579293329e-06 -772.24893445455 219.395418012503 -3.5198954538355 0.000477039537787787 RING1 other 1.31889541891298e-07 1 0.0778450352274843 4.49448950403649 -3.5198954538355 0.0251111080093945 7.09261605805821 19.1960444200298 0.369483207209999 0.711946560198677 -105.262988135007 44.7437593302236 -2.35257362614822 0.0190865812730885 HSD17B8 other 1 1 1 0.369483207209999 -2.35257362614822 1.71128993585981e-14 134.756911646129 68.904432532303 1.9557074442628 0.0511364323446397 -1069.82559612948 160.608262751989 -6.66108690672719 8.19230657749438e-11 RXRB other 1.36458259485461e-10 7.75483740625618e-07 1 1.9557074442628 -6.66108690672719 4.94549259373808e-06 130.525242006343 26.5529912555217 4.91565115019576 1.25502098584372e-06 0.926488148135047 70.023075200304 0.0132311833704074 0.989449403173729 OXLD1 other 0.0283624000250879 1 0.0112198876134429 4.91565115019576 0.0132311833704074 0.0330248512527392 -42.4460027646548 63.6311045398273 -0.667063742985751 0.505083480061593 -385.262469761544 148.316745114196 -2.59756556459564 0.00970564177102987 COL11A2 other 1 1 1 -0.667063742985751 -2.59756556459564 0.0774626481832888 433.245938375353 207.547635760768 2.08745301668836 0.0374245862780254 784.000739783091 483.759188328649 1.62064258147066 0.105813978583627 HLA-DOA other 1 1 1 2.08745301668836 1.62064258147066 4.87714079210614e-06 346.905042016808 261.228138905506 1.32797731312665 0.184877208420563 -2409.69269553974 608.879556648838 -3.95758515658212 8.83131619980605e-05 BRD2 other 0.0279801567243129 0.706152043336491 1 1.32797731312665 -3.95758515658212 0.00158779370281528 601.59159663866 201.720948758831 2.98229608942548 0.00302063370371485 1426.43910795087 470.178145285831 3.03382690636058 0.00255839053405094 HLA-DMA other 1 1 1 2.98229608942548 3.03382690636058 0.199790155963412 182.305882352943 105.897860997166 1.7215256345718 0.0858615620171132 281.243137254901 246.830387125098 1.13941861263768 0.255151340488587 PSMB8-AS1 other 1 1 1 1.7215256345718 1.13941861263768 0.0600900085468101 263.407563025213 122.072146931785 2.1578023295716 0.0314861768573842 498.763520792934 284.52997067779 1.75293843247799 0.0803121616688838 PSMB8 other 1 1 1 2.1578023295716 1.75293843247799 0.22511141216161 258.159663865549 156.484724798409 1.64974354013225 0.0997123184348613 55.4748976513684 364.739994155211 0.152094364589373 0.879182541710304 TAP2 other 1 1 1 1.64974354013225 0.152094364589373 0.561301826349001 -44.7968828155925 42.6506054788166 -1.05032231811672 0.294149105223372 -45.4102083339724 119.861950744193 -0.378854240666297 0.704979683528178 TMEM235 other 1 1 1 -1.05032231811672 -0.378854240666297 0.27478137615776 -61.9657533195652 40.2211729827344 -1.54062521613094 0.124130145023713 -77.109199652623 113.034462249888 -0.682174251266446 0.495489360635284 TNRC6C-AS1 other 1 1 1 -1.54062521613094 -0.682174251266446 0.0258928863386743 4757.43361344541 2135.97065565936 2.22729352617292 0.0264351228562434 11387.7769015298 4978.59407980258 2.28734793778997 0.0226515493000096 HLA-DRA other 1 1 1 2.22729352617292 2.28734793778997 0.21132660398871 -10.0469441984049 25.1230171510407 -0.399909936692804 0.689418252074755 79.9414265617682 55.1415131223727 1.44975032484797 0.147845431626996 COL15A1 other 1 1 1 -0.399909936692804 1.44975032484797 0.0392959663425729 4.21316526610688 72.3146126153462 0.0582616032048381 0.953566822158687 -393.648021259785 168.553393416747 -2.33544999172157 0.0199705478318753 NOTCH4 other 1 1 1 0.0582616032048381 -2.33544999172157 1.6371409991113e-06 76.6969187675073 49.3349716285642 1.55461564556979 0.120759871316028 -463.016856999208 114.991653572777 -4.02652577481348 6.67102994161633e-05 PBX2 other 0.00976063463670159 0.537751723593692 1 1.55461564556979 -4.02652577481348 0.359768282159011 19.1210084033617 19.0183405122493 1.00539836223072 0.315260168670741 -24.6272570566685 44.3286040616159 -0.555561303541999 0.578794437202051 AGER other 1 1 1 1.00539836223072 -0.555561303541999 4.56538249655281e-10 247.445658263306 63.1451468132347 3.91868054397243 0.000103277225179979 -521.328298498887 147.180886244708 -3.54209239936297 0.000439570658142513 RNF5 other 3.29757577726009e-06 1 0.857510800669367 3.91868054397243 -3.54209239936297 8.47025040221346e-17 94.1426979508446 10.677810204139 8.81666710224462 2.82457660510996e-17 45.8566674921066 24.1186771947842 1.90129280813225 0.057921179167016 FKBPL other 6.99727385726854e-13 1 2.75057269805608e-13 8.81666710224462 1.90129280813225 0.198620232507123 15.338672621476 17.0986694243799 0.897068201085026 0.37017872138424 -45.3626493175591 39.5173655038561 -1.14791683957607 0.251633789128051 CYP21A1P other 1 1 1 0.897068201085026 -1.14791683957607 0.00161642124649643 135.745427551882 50.2501386980755 2.70139408703922 0.00717349861714552 -138.241230380281 112.663926454047 -1.22702301199015 0.220474573994548 STK19 other 1 1 1 2.70139408703922 -1.22702301199015 4.12655051914957e-06 148.307197183655 31.8859796031771 4.65117267932008 4.3772309596501e-06 -7.68716092844843 71.4886192006133 -0.107529856002345 0.914417877981347 DXO other 0.0238225761470505 1 0.0385371413687595 4.65117267932008 -0.107529856002345 0.000472813407805574 238.944822467721 77.7287302085664 3.07408627191735 0.00224345299001643 -202.641231100659 174.268429697977 -1.16281090873347 0.245539369107179 SKIV2L other 1 1 1 3.07408627191735 -1.16281090873347 0.285276743078675 -3.43814956397085 11.0365038851066 -0.311525243841984 0.755549917766461 -35.4609664317286 22.8299861938926 -1.55326271906441 0.12108426976317 C9orf129 other 1 1 1 -0.311525243841984 -1.55326271906441 2.00505591390757e-07 71.0723856187688 32.302514111884 2.20021219935391 0.0283132826584924 -291.343767651426 72.4224928732257 -4.02283539399035 6.77265424563048e-05 ZBTB12 other 0.00127000241586906 0.54580820565536 1 2.20021219935391 -4.02283539399035 6.23558802777608e-10 437.115182523944 168.076261992792 2.60069552559831 0.00961818264989766 -1787.89271874631 376.828312625152 -4.74458170696109 2.83261792715192e-06 EHMT2 other 4.47839932154878e-06 0.0245616300463343 1 2.60069552559831 -4.74458170696109 0.000157952444462755 187.330839121736 56.9371328332732 3.29013474686703 0.00108229371102949 -161.140166072471 128.581243297278 -1.25321673628492 0.21079541891382 NEU1 other 0.76417392631081 1 1 3.29013474686703 -1.25321673628492 4.2858603136791e-08 867.10507687882 230.236695421789 3.76614629258078 0.00018842245274749 -1498.2915868034 519.943999229446 -2.88164030938689 0.00415055418683598 C6orf48 other 0.000282266760258906 1 1 3.76614629258078 -2.88164030938689 0.663324712727544 2371.33834438218 3081.54962986084 0.769527876949775 0.441994793102121 -1125.96461667262 6959.06981916416 -0.161798149168139 0.871539419595057 HSPA1B other 1 1 1 0.769527876949775 -0.161798149168139 0.64192330129337 2260.78638451368 2853.91960154176 0.792168911588239 0.428691017263058 -1172.93965731802 6445.01246157348 -0.181991836991989 0.855673327715149 HSPA1A other 1 1 1 0.792168911588239 -0.181991836991989 0.0205563390291209 3.05459252770833 12.1043918381165 0.252354068552992 0.800885776987424 -68.3122181891051 27.3353727954651 -2.4990410301058 0.0128181610703247 HSPA1L other 1 1 1 0.252354068552992 -2.4990410301058 1.02697635597027e-11 331.993603397729 52.0544784881011 6.3778105753882 4.56953373742065e-10 -117.178041456703 117.554735023117 -0.996795590017372 0.319414097020034 LSM2 essential 7.73929381859192e-08 1 4.32140805547871e-06 6.3778105753882 -0.996795590017372 7.97524439510025e-08 679.77519126778 160.789928922019 4.22772244396887 2.87510890959863e-05 -787.188549467804 363.112224688494 -2.16789327361015 0.0307047028767515 VARS essential 0.000517752866129908 1 0.245016781275995 4.22772244396887 -2.16789327361015 0.200242858559535 -14.6635432457504 11.362196180936 -1.29055536555103 0.197538732056153 17.6139703862201 25.659270827887 0.686456388584391 0.492788590991337 VWA7 other 1 1 1 -1.29055536555103 0.686456388584391 6.30879474701679e-05 158.67568353788 37.443965943057 4.23768368391282 2.75531711495494e-05 26.0963498317623 84.5597847197112 0.308614194303632 0.757761751384878 MSH5 other 0.320652729318084 1 0.235028549905657 4.23768368391282 0.308614194303632 8.65616252845413e-06 120.040800561117 50.9758205572051 2.35485764130873 0.0189701643254609 -359.14127473067 115.118799616021 -3.11974478476658 0.00192964587779603 ABHD16A other 0.0484398855092293 1 1 2.35485764130873 -3.11974478476658 0.00383622180808456 31.5888041682961 11.3197345924643 2.79059583157763 0.00549092755267105 -18.0494694278614 25.5633797359689 -0.70606741417939 0.480521597308867 LY6G5C other 1 1 1 2.79059583157763 -0.70606741417939 1.80458677424359e-13 904.746653823896 134.466196528068 6.72843195676352 5.38224341697168e-11 -428.80953381407 303.665286091314 -1.41211245886408 0.15862691225632 CSNK2B essential 1.41245006820046e-09 1 5.1314308737408e-07 6.72843195676352 -1.41211245886408 3.94187478959432e-08 180.59876916314 46.3025666636152 3.9004051433083 0.00011110785220396 -287.074784328806 104.565180809096 -2.74541469834893 0.00629215739839562 GPANK1 other 0.000260124317365329 1 0.920972986918623 3.9004051433083 -2.74541469834893 7.67643724548887e-13 148.239327952731 26.0571045262451 5.68901766516008 2.34020184431267e-08 -161.57003455264 58.8448123392993 -2.74569716733953 0.00628683618322471 C6orf47 other 5.9277448409665e-09 1 0.000216398464543593 5.68901766516008 -2.74569716733953 0.0028184637023196 -128.86067256272 155.337529790279 -0.829552734208496 0.40724358272465 -677.928242344486 218.418861458843 -3.103798993441 0.00203432743778468 FAM155A other 1 1 1 -0.829552734208496 -3.103798993441 4.68750466087121e-06 -4.89750568066105 8.9222298981504 -0.548910500689555 0.58334657501196 -97.6181432076091 20.1490899910207 -4.844791663103 1.76180742417571e-06 APOM other 0.026934401781366 0.0154105295392649 1 -0.548910500689555 -4.844791663103 2.55008653269606e-12 1071.94665834903 223.742472632677 4.79098423171925 2.275812586735e-06 -1839.65852357756 505.278082648808 -3.64088328140725 0.0003041714825905 BAG6 other 1.94750108501998e-08 1 0.0202023883324466 4.79098423171925 -3.64088328140725 3.50986507451088e-08 1373.58874276697 489.253164071913 2.8075214298769 0.00521539824411723 -4063.37138348236 1074.80232291239 -3.78057555036899 0.000178155787118529 PRRC2A other 0.00023235306793262 1 1 2.8075214298769 -3.78057555036899 0.00110451425994106 467.859147816939 129.785914087019 3.60485304671235 0.000348226131027885 637.568948673626 285.116606668551 2.23616911032756 0.0258435428815793 AIF1 other 1 1 1 3.60485304671235 2.23616911032756 0.00344838406594793 134.40927932667 45.8970304137034 2.92849620367901 0.00358374956048477 272.788908093482 100.82762570786 2.70549768655535 0.00708632082739055 LST1 other 1 1 1 2.92849620367901 2.70549768655535 4.80890162269572e-06 284.976980536561 74.1734418571146 3.84203528111224 0.000140053125469299 -243.347411136996 162.94588049862 -1.4934247517786 0.136046027314914 NFKBIL1 other 0.0276030953142734 1 1 3.84203528111224 -1.4934247517786 1.19174157113156e-46 226.796738883419 40.5879333341625 5.58778731146989 4.05269212149137e-08 -109.937903579388 50.6390077564626 -2.17101219889835 0.0304677996403835 ZNF814 other 1.13060522853251e-42 1 0.000373374525153 5.58778731146989 -2.17101219889835 0.0573114663690543 8.32495943670605 11.0211462241966 0.755362397645069 0.450438493094411 57.4981631715909 24.0395250027395 2.3918177736473 0.0171869899515406 MICB other 1 1 1 0.755362397645069 2.3918177736473 4.78275399900905e-35 17.6405337733367 15.6918476391014 1.12418461987736 0.261551846847973 -103.701292317633 19.6816540315487 -5.26893177531749 2.15944205051252e-07 ZNF551 other 4.40491643308733e-31 0.00194392973387137 1 1.12418461987736 -5.26893177531749 0.00142056705675655 -19.3533316352678 14.3569895836329 -1.34800763924289 0.178355855882713 81.4592540991402 31.3166167232541 2.60115116581711 0.00960706742822674 MICA other 1 1 1 -1.34800763924289 2.60115116581711 2.42438904324176e-24 11.539673997614 4.96033306418553 2.32639095969834 0.0204541617545994 -17.6662819648323 6.19054770983986 -2.8537510399527 0.00452599872513936 ZNF805 other 2.13782625833059e-20 1 1 2.32639095969834 -2.8537510399527 0.25790937752474 3405.78014874971 2075.76123790216 1.64073790692407 0.101569703796098 3591.58333505982 4592.21021451656 0.78210342455717 0.434576384668006 HLA-C other 1 1 1 1.64073790692407 0.78210342455717 8.81319093105552e-13 254.959228490335 33.7356341325643 7.5575644284163 2.42391257624492e-13 117.944214417418 74.6334023528275 1.58031405107113 0.114756809483099 CCHCR1 other 6.7932075696576e-09 1 2.33980280984922e-09 7.5575644284163 1.58031405107113 0.267061399381838 3.28248290373487 4.88924671801536 0.671367818613026 0.502340153384412 17.4728338468474 10.74080683726 1.62677107144632 0.104504894457759 CDSN other 1 1 1 0.671367818613026 1.62677107144632 0.390488290388112 20.556589115167 17.4263041761727 1.17962988063036 0.238787768873189 42.4902111085794 38.5522431857188 1.10214627210899 0.271003327466172 PSORS1C1 other 1 1 1 1.17962988063036 1.10214627210899 0.88679089310517 -15.1781588637559 31.2245589270289 -0.486096822031239 0.627141621502779 -16.920568122041 68.5948112984559 -0.246674169689302 0.805275967114048 C6orf15 other 1 1 1 -0.486096822031239 -0.246674169689302 1.44509818059806e-08 143.022535507629 36.8478251351084 3.88143764206475 0.000119827481439393 -233.26775381378 80.9481286127414 -2.88169421346034 0.0041498576827743 DHX16 essential 9.79776566445485e-05 1 0.991692236392419 3.88143764206475 -2.88169421346034 0.00016035329702858 32.3412519726461 23.4691693413503 1.3780313867208 0.168897167907602 -162.340272037273 51.5575975328792 -3.14871677125268 0.00175205222239754 C6orf136 other 0.775147837836155 1 1 1.3780313867208 -3.14871677125268 2.84554073567158e-11 376.433308784852 64.7330431131334 5.81516472394111 1.16924850206309e-08 -229.797249567896 142.207000825767 -1.61593485716955 0.106828415024586 MRPS18B essential 2.122773388811e-07 1 0.000108623185841661 5.81516472394111 -1.61593485716955 0.000286256523325563 451.808185165705 150.01050224587 3.01184369361808 0.00274701242538689 -451.806868565414 329.546435496157 -1.37099607187432 0.171078242244389 PPP1R10 essential 1 1 1 3.01184369361808 -1.37099607187432 1.57684543734896e-14 672.020999473966 107.519250262916 6.25023889053059 9.7309729246155e-10 -609.499736980532 236.200700223564 -2.58043154149688 0.010192204859305 ABCF1 essential 1.258007289917e-10 1 9.17728056520488e-06 6.25023889053059 -2.58043154149688 2.18918107107589e-09 186.880631246714 53.3164024982329 3.50512454873353 0.000503420541702783 -427.744194784697 117.126668691323 -3.65197951554465 0.000291695703607544 PRR3 other 1.53855645675214e-05 1 1 3.50512454873353 -3.65197951554465 5.8527123825695e-13 497.008732246191 177.686389407814 2.79711200110825 0.00538332783522277 -2181.50898023595 390.345445077924 -5.58866257501854 4.02869264267286e-08 GNL1 other 4.52999938410879e-09 0.000368625376804567 1 2.79711200110825 -5.58866257501854 0.0446428450762956 3110.34901630722 1342.96729685817 2.31602736982783 0.0210176650484428 5219.77756068231 2950.2606753635 1.76925978245607 0.0775463429920437 HLA-E other 1 1 1 2.31602736982783 1.76925978245607 5.00592557794136e-25 36.2030464476552 10.9665044577507 3.30123847458689 0.00104229167649086 -61.1815497834129 16.3843939732405 -3.73413565880658 0.000213524090066515 ZNF468 other 4.43224650670928e-21 1 1 3.30123847458689 -3.73413565880658 4.88126592491378e-23 41.8992094493186 16.8330414765456 2.48910510365575 0.0131810563235514 -55.2794452161425 20.9805289251724 -2.63479750264152 0.00872066732123465 ZNF616 other 4.27354831726202e-19 1 1 2.48910510365575 -2.63479750264152 1.84730045023868e-06 10.4906800880143 7.48460327858951 1.40163475571564 0.161732553337521 -64.6754175202548 16.0330132373487 -4.03389035877511 6.4725388678853e-05 RNF39 other 0.0109618808717163 0.522139710472307 1 1.40163475571564 -4.03389035877511 5.65774124221553e-14 59.0307544449766 58.7418507576176 1.00491819177695 0.315491080780819 -873.539644401737 125.832837857604 -6.94206424391587 1.40019915714738e-11 PPP1R11 essential 4.4730102260956e-10 1.3348098565086e-07 1 1.00491819177695 -6.94206424391587 0.441628101449225 182.332026606644 142.69365508311 1.27778650354458 0.202001520228279 137.860374145363 305.668740970907 0.451012340049793 0.652203853574729 HLA-J other 1 1 1 1.27778650354458 0.451012340049793 0.530505707200867 65.6380788588492 69.9119359675661 0.938867990857818 0.348315967567324 -28.7256211167031 149.760642360713 -0.191810215714184 0.847979758436484 ZNRD1ASP other 1 1 1 0.938867990857818 -0.191810215714184 0.336710223089472 -184.758848525903 132.203997284708 -1.39752845844755 0.1629637829474 -157.679793336439 168.993517152449 -0.933052320546687 0.351308184170503 DISP3 other 1 1 1 -1.39752845844755 -0.933052320546687 0.00287686171452108 4232.96945084255 1740.30801301975 2.43231049858673 0.0154052344437555 -4003.21938012691 3520.89483134619 -1.13698919504401 0.256168724876599 RACK1 other 1 1 1 2.43231049858673 -1.13698919504401 0.487724423299557 67.216318065708 56.3479630962664 1.19287928741761 0.233562440088247 71.7440417478109 120.704812879585 0.594375982500239 0.552567551742846 HLA-G other 1 1 1 1.19287928741761 0.594375982500239 0.595993141021186 177.218796631176 177.658010437449 0.997527756811013 0.319059170708705 223.714256809736 380.567029011784 0.587844557608298 0.556939580307071 HLA-F other 1 1 1 0.997527756811013 0.587844557608298 0.524086841152198 0.421027340094607 7.67231424882635 0.0548761855210783 0.956262126210595 17.4541170321287 16.4351150400204 1.06200151259222 0.288820199998161 ZFP57 other 1 1 1 0.0548761855210783 1.06200151259222 0.000166447820005554 143.270720231632 41.9709436329471 3.41356919407371 0.000700964889434921 -185.771552660152 97.4560241641009 -1.90620902354216 0.057278822802996 LINC02210 other 0.802278492426768 1 1 3.41356919407371 -1.90620902354216 3.26958659548568e-09 -38.8460601451463 26.1897309294706 -1.48325541219799 0.138725744551965 49.4405306320309 32.0314684227406 1.54349872380283 0.123431978091275 ASPDH other 2.27857489839397e-05 1 1 -1.48325541219799 1.54349872380283 0.318199599553778 -461.097574546653 457.682506559825 -1.00746165286608 0.314269208512259 617.492281882028 980.416651764004 0.629826391433695 0.529136582664446 MOG other 1 1 1 -1.00746165286608 0.629826391433695 4.76010758195149e-49 304.762635494505 68.8781355982162 4.42466441415115 1.22048934592308e-05 -307.000092545054 84.1217871230446 -3.64947183178605 0.000294472354452466 AKT1S1 other 4.53590651484157e-45 1 0.105682172463479 4.42466441415115 -3.64947183178605 0.000455368047304025 -2955.9924631377 1536.13609130972 -1.92430376439981 0.0549640611063214 -12966.6075773288 3290.60731338845 -3.94049071871072 9.46158358903468e-05 GABBR1 other 1 0.754750522897296 1 -1.92430376439981 -3.94049071871072 2.08011829175637e-23 2.57252936965767 7.57541508965097 0.339589229001073 0.734329035827412 134.601617675768 14.8564008097303 9.06017678168791 4.38605790045605e-18 CASC10 other 1.82530380101621e-19 4.29351207875643e-14 1 0.339589229001073 9.06017678168791 0.79812542644867 2.19133010763316 3.2622920176312 0.671714885053215 0.502120160231714 1.97740199466778 7.0496189969824 0.280497711367694 0.779228421453476 MAMDC2-AS1 other 1 1 1 0.671714885053215 0.280497711367694 2.10065820414147e-10 296.082190804701 73.0755573679966 4.05172675336132 6.01479446976131e-05 -507.772263143585 152.956349418087 -3.31972007095733 0.000976402350455569 TRIM27 other 1.52990937007623e-06 1 0.505363031349346 4.05172675336132 -3.31972007095733 0.484789383149357 25.4327823021771 23.4559725794329 1.08427745709754 0.278839628181817 3.94508933997912 43.0424121146271 0.091655860955768 0.92701346691225 RANBP17 other 1 1 1 1.08427745709754 0.091655860955768 0.00104015377275306 -15.6334282711667 21.1682597289153 -0.738531578475099 0.460588837891871 -137.400688426216 38.8459904134976 -3.53706230588148 0.000447993497785103 FAM196B other 1 1 1 -0.738531578475099 -3.53706230588148 0.36034697706166 17.4118626978214 18.4645404494092 0.942989225511896 0.346206249318282 -32.5445764470358 40.7665707963957 -0.798315281645253 0.425120178112744 TTC25 other 1 1 1 0.942989225511896 -0.798315281645253 0.257978712461021 10.0695759602759 6.51345690052946 1.54596493291563 0.122835227580429 20.3051654064095 19.1087161343109 1.0626127503119 0.288543117673884 MROH6 other 1 1 1 1.54596493291563 1.0626127503119 1.34356365410151e-11 -8.38999549853717 55.1215693459599 -0.152208937410308 0.879092231791277 -556.281331205365 92.2031280071133 -6.03321539332645 3.42393693649135e-09 ATXN2 other 1.01009115515351e-07 3.1839189572433e-05 1 -0.152208937410308 -6.03321539332645 3.99088419811687e-05 372.746511366195 98.8669558326823 3.77018295169332 0.000185495438145076 15.1680477973546 165.37705098889 0.0917179723949341 0.92696404978992 TCTN1 other 0.208098456175502 1 1 3.77018295169332 0.0917179723949341 3.21357332482092e-09 17.3107697501691 29.424039523864 0.588320639527737 0.556620328286023 -239.243999754464 49.2182736249334 -4.86087751833022 1.63125593938932e-06 FAM216A other 2.24146739406259e-05 0.0142849082612323 1 0.588320639527737 -4.86087751833022 3.50093009714934e-38 160.53883783162 27.9640881324435 5.74089300073995 1.76188084433301e-08 -75.2897429377505 35.7511066169074 -2.10594160747306 0.0357779511771888 ZBTB48 other 3.25411452530031e-34 1 0.00016332635426967 5.74089300073995 -2.10594160747306 1.56058477295514e-10 121.412538986741 35.6490926191567 3.40576800323656 0.000721196889052574 -49.3996893220406 41.3953459064946 -1.19336336586307 0.233379030666651 MZT1 other 1.14125564446209e-06 1 1 3.40576800323656 -1.19336336586307 4.38367816689214e-66 115.952293496452 12.8541786543638 9.02059140566626 5.99296678018381e-18 -17.4185855837366 16.0247732909392 -1.08697859666978 0.277646817958616 ZNF155 other 4.26838743110288e-62 1 5.84134472064516e-14 9.02059140566626 -1.08697859666978 0.25744140759217 12.7317145809547 21.6190186875076 0.58891269603794 0.556223430698413 -66.5117480630481 52.3686955877261 -1.27006692293166 0.204735081438062 LRRC10B other 1 1 1 0.58891269603794 -1.27006692293166 1.12872455613164e-07 45.9184806939004 11.574684993704 3.96714733220625 8.50225505938578e-05 -28.3949496362621 20.2706945000708 -1.40078819875475 0.161988720207007 C12orf73 other 0.000723963930302835 1 0.709513184705744 3.96714733220625 -1.40078819875475 0.000194740204499464 -1855.92371157313 2810.8449195924 -0.660272538921233 0.509426818415235 -24158.2836182805 5926.15810343752 -4.07655064151381 5.43075508800833e-05 PCDHGA1 other 0.929105515666945 0.440814390493636 1 -0.660272538921233 -4.07655064151381 0.00263996890624013 -119.746531219028 145.131675659293 -0.825088876532656 0.409773361914079 -1051.8810703667 305.997005611107 -3.4375534762701 0.000643491193989706 PCDHA9 other 1 1 1 -0.825088876532656 -3.4375534762701 0.00339481955178261 -104.058158861909 140.2162903457 -0.742126029759854 0.458411494878226 -991.342232408328 295.633360455411 -3.3532826974642 0.000868458104350572 PCDHA8 other 1 1 1 -0.742126029759854 -3.3532826974642 0.00279353638857792 -130.036613189626 138.028424703802 -0.942100248326927 0.346664216604425 -999.835666501489 291.020443722665 -3.43562003312147 0.000647977248496433 PCDHA7 other 1 1 1 -0.942100248326927 -3.43562003312147 0.00228763335670734 -140.162454575487 138.873334469159 -1.00928270435253 0.313400141543229 -1024.56987115957 292.801859509649 -3.49919181823298 0.00051478150104327 PCDHA5 other 1 1 1 -1.00928270435253 -3.49919181823298 0.00349729004430621 -160.005265113974 150.47276357251 -1.06335034537244 0.288213033559287 -1072.28766105055 317.258206177596 -3.37985792068149 0.000790632691650375 PCDHA4 other 1 1 1 -1.06335034537244 -3.37985792068149 0.00234140376234167 -129.227225801123 142.02931416017 -0.909863055843461 0.36339859427684 -1042.82631318137 299.455957113303 -3.48240296581178 0.000547220480447495 PCDHA2 other 1 1 1 -0.909863055843461 -3.48240296581178 0.00216019710475847 -180.439047106541 151.235036387144 -1.19310347269424 0.233480679883565 -1124.5998427022 318.872272210626 -3.52680349064455 0.000465420301758666 PCDHA1 other 1 1 1 -1.19310347269424 -3.52680349064455 3.49364573098998e-22 266.982306055955 61.6401437169968 4.33130570366171 1.84213404572107e-05 -181.689829550043 72.6061304131004 -2.50240342676712 0.0127013069589797 TRIM13 other 3.04436288998467e-18 1 0.158220893186983 4.33130570366171 -2.50240342676712 0.243715915388961 37.2319419170346 43.7765693898939 0.850499306727992 0.395514363193331 -86.9931481412721 90.234353580562 -0.964080138986133 0.335540153416504 SPIRE2 other 1 1 1 0.850499306727992 -0.964080138986133 0.217185992287236 7.73378014649805 8.8942477418275 0.869526054477654 0.385036795866899 24.955608821994 14.3423584842513 1.73999338040508 0.0825641734463971 LINC02397 other 1 1 1 0.869526054477654 1.73999338040508 4.221765419706e-05 14.8796101498434 3.49185849793794 4.26122941655005 2.49193075916305e-05 0.310710145549857 8.059242773196 0.0385532678806052 0.96926416726241 SYCE1L other 0.219447366516318 1 0.212985321985666 4.26122941655005 0.0385532678806052 0.675875680934603 -4.51139855871642 92.4886920174711 -0.0487778393261764 0.961118576897591 -180.253173999791 213.461192753801 -0.844430651184871 0.398889784015437 TMEM231 other 1 1 1 -0.0487778393261764 -0.844430651184871 2.23833757838038e-16 42.0110991005388 14.0981411621459 2.97990342254058 0.00304384781729489 -42.965044003037 18.6975896833174 -2.29789212036094 0.0220383973678266 TMEM240 other 1.83677981681894e-12 1 1 2.97990342254058 -2.29789212036094 0.38479359655229 -6.36702891195125 4.70705899559862 -1.35265543047257 0.176865192792014 -5.90408367055441 6.24596693936181 -0.945263355998113 0.345046785911008 TMEM88B other 1 1 1 -1.35265543047257 -0.945263355998113 0.0260320141010832 17.3007964059634 15.8442486696165 1.09192911363099 0.275465886308092 -19.902579810768 20.9310829928575 -0.950862400075499 0.342199816942422 C4orf47 other 1 1 1 1.09192911363099 -0.950862400075499 6.32398284595257e-42 104.164544309013 15.9278729269394 6.5397649006124 1.73185438203005e-10 -41.3752582773968 20.9496578068895 -1.97498492141433 0.0489017123262016 SDHAF1 other 5.9325283077881e-38 1 1.64456892117574e-06 6.5397649006124 -1.97498492141433 1.1005022532121e-53 298.291010610069 68.5372289402558 4.35224789829322 1.68129270503208e-05 -522.469556423655 90.5486088744419 -5.77004509421156 1.50704088219904e-08 PSENEN other 1.05725251466086e-49 0.000138873817294642 0.144708863122111 4.35224789829322 -5.77004509421156 1.02928915587515e-07 83.9809560847193 17.7932685721355 4.71981613407638 3.18340023555654e-06 26.4134139045113 24.2787871943575 1.08792147206801 0.277229419971747 C4orf46 other 0.000663068074214774 1 0.0281508082830265 4.71981613407638 1.08792147206801 7.51189863596722e-25 0.207069364880585 1.56817721155113 0.132044620566681 0.89500991143977 -12.3058943682869 2.07036194858588 -5.94383720039494 5.70704849654628e-09 SCGB2B2 other 6.64352315364941e-21 5.28872184174944e-05 1 0.132044620566681 -5.94383720039494 0.000443507022582576 -2.72141790031296 83.278182938661 -0.0326786416835899 0.973945844864745 -315.44844945448 104.240604356108 -3.02615714291948 0.00262382789788337 LGR4 other 1 1 1 -0.0326786416835899 -3.02615714291948 0.0422214623063466 138.741468481298 79.2204913972601 1.75133309620062 0.0805884925165393 424.239110958815 182.838574265997 2.32029325683553 0.0207836547225719 PSMB10 other 1 1 1 1.75133309620062 2.32029325683553 1.31124603920655e-05 197.15937486583 44.1646361474872 4.46419108282516 1.02420453314883e-05 -8.2983913671935 101.932402161387 -0.0814107309475046 0.935152587560125 E2F4 other 0.0720136324732237 1 0.0889316796133132 4.46419108282516 -0.0814107309475046 2.21925009441436e-07 8.81944929319488 97.6584443934481 0.0903091314629478 0.92808313138343 -819.442782016962 171.536913892624 -4.77706380173019 2.43577008207611e-06 TMEM170B other 0.00140278798467931 0.0211814566337339 1 0.0903091314629478 -4.77706380173019 7.12784453785612e-08 48.8648349896738 22.973330984152 2.12702437549796 0.0339763145820204 -94.881114252845 17.0509584772025 -5.56456192065115 4.58470837786985e-08 NT5M other 0.000463381173406027 0.000419088192821083 1 2.12702437549796 -5.56456192065115 1.05785860544508e-06 228.5379978421 61.4865676838061 3.71687681474356 0.000227967707749509 -90.6474058263354 96.7829392213988 -0.936605217361421 0.349480158879212 SARNP essential 0.00640110242154818 1 1 3.71687681474356 -0.936605217361421 0.137097140376257 -72.9943647062443 1401.13677435512 -0.0520965305045542 0.958475528255614 -6197.79316500101 3280.73041094841 -1.88915039904462 0.0595319835028125 ADGRG1 other 1 1 1 -0.0520965305045542 -1.88915039904462 2.5419381532811e-15 1168.66971014823 297.508569412778 3.92818839623662 9.94796962240677e-05 -849.000470021107 360.389479011211 -2.35578594677759 0.0189254613057743 IPO7 essential 2.05414022166645e-11 1 0.827074194406899 3.92818839623662 -2.35578594677759 0.069901530758727 161.055965909091 69.8706367004716 2.30505937135684 0.0216310045319981 130.705237926139 106.763515761059 1.2242500351774 0.221517507974818 PRR13 other 1 1 1 2.30505937135684 1.2242500351774 0.695154519524989 1.55132059115484 8.24538116116625 0.188144193801638 0.8508509518331 16.1276443282389 19.0025748579945 0.848708369721481 0.396508242986817 MT1H other 1 1 1 0.188144193801638 0.848708369721481 0.109061102059393 54.6771437759526 26.0872114159804 2.09593669879406 0.0366624577410598 26.047933474083 60.1214398799703 0.433255316673828 0.665043066029204 MT1A other 1 1 1 2.09593669879406 0.433255316673828 0.261729067699074 -104.583656099067 239.756103107735 -0.436208525011235 0.662900858748231 -657.45300371379 423.296227901003 -1.55317472818952 0.121105283790003 C15orf59 other 1 1 1 -0.436208525011235 -1.55317472818952 1.01704464517878e-05 241.243508899484 91.7296379820756 2.62994070625924 0.00884140398105985 995.82759259517 211.403121138984 4.71056239486869 3.32407790482525e-06 MT1M other 0.0564968300396815 0.0287333294093094 1 2.62994070625924 4.71056239486869 0.140128116323282 -132.071353482259 179.392239616449 -0.736215533986504 0.461993640509807 -476.165308804208 252.176820417315 -1.88821997206652 0.0596570547719336 CFI other 1 1 1 -0.736215533986504 -1.88821997206652 0.44583630336314 19.7967167679351 15.5605021152064 1.27224151388976 0.203965420348513 18.5072240945282 27.8701796400881 0.66405112322662 0.507008595257103 KRT6A other 1 1 1 1.27224151388976 0.66405112322662 2.44938929639348e-06 62.7136568002994 14.1707832631198 4.42556036853059 1.21565103030146e-05 -50.8263394529787 36.2064878032637 -1.40379093739098 0.161089715407875 CNEP1R1 other 0.0144073078413864 1 0.105287535734409 4.42556036853059 -1.40379093739098 1.29902292506267e-33 259.575633576127 126.479298692051 2.05231714802701 0.0407326322369219 -950.581880677634 149.722633218893 -6.34895246123474 5.42738602721536e-10 CCDC85C other 1.19146382686748e-29 5.10065738837699e-06 1 2.05231714802701 -6.34895246123474 2.27722880003658e-36 1060.52857548496 178.373659356833 5.94554475873252 5.6434670053533e-09 -705.575330089452 207.381849062536 -3.40230031354714 0.000729730802106901 NAP1L4 other 2.10666436291384e-32 1 5.27269122310159e-05 5.94554475873252 -3.40230031354714 0.000793232234755183 173.980664673102 48.4517865733703 3.59079978216374 0.000366979904836601 -50.7011009922522 36.2177773839044 -1.39989542855781 0.162252526012155 TMEM256 other 1 1 1 3.59079978216374 -1.39989542855781 0.000141169137099833 128.502457044092 70.1057293471283 1.83298081684327 0.0674871106182928 -170.264664128662 102.966032537536 -1.6536003178193 0.0989285149579149 CPT1B other 0.686505513716486 1 1 1.83298081684327 -1.6536003178193 1.85032794416577e-07 883.882722574585 177.927729288193 4.96765021455955 9.73337664175895e-07 -17.494630692303 346.536436487954 -0.0504842459557962 0.959759517154911 HMGN1 other 0.0011742181133676 1 0.00873375886065031 4.96765021455955 -0.0504842459557962 0.00012293423528473 115.419084103259 57.1955161575201 2.01797434234858 0.0442045268807069 -125.090783444752 83.9944910879034 -1.48927366336251 0.137136640360848 DENND6B other 0.602377752895178 1 1 2.01797434234858 -1.48927366336251 9.34511722190461e-06 -1.96920852421927 2.60455083945841 -0.756064536881431 0.450016934864785 -15.6995621017617 3.82446119151001 -4.10503893636403 4.82296551440513e-05 LINC01310 other 0.0521364089810058 0.392927000458586 1 -0.756064536881431 -4.10503893636403 1.13526037701604e-09 41.8538125303545 14.1093438293425 2.96638972276749 0.00317843591095283 -49.0519559362442 20.6245858400156 -2.37832440935973 0.0178204705935249 CDPF1 other 8.07056602020706e-06 1 1 2.96638972276749 -2.37832440935973 8.52752131200384e-27 4.10644412803772 24.7035734916619 0.166228749432698 0.868053640246002 -167.05578155958 28.0899663004138 -5.94716916969455 5.58322319015799e-09 LIN52 other 7.62019304440663e-23 5.17620621959547e-05 1 0.166228749432698 -5.94716916969455 4.76946098201916e-09 40.0580793917868 11.7064956406966 3.42186770672245 0.000680461291618757 -78.1862475407056 23.1329418018677 -3.3798661757059 0.000790302357648792 SMIM11A other 3.30285173004827e-05 1 1 3.42186770672245 -3.3798661757059 3.40273483950412e-11 -111.727338215873 55.4204570043694 -2.01599453081133 0.0444106139290725 -333.477368231479 63.0730434870876 -5.28716151615148 1.9647325934576e-07 DPF3 other 2.53435690846267e-07 0.00176943817366791 1 -2.01599453081133 -5.28716151615148 1.81428274545036e-06 25.8600111326277 9.45976646040699 2.73368388541751 0.00651735566315713 -22.1100692783908 14.0291906822998 -1.57600461630951 0.115748356819084 CYP2D7 other 0.0107750252252297 1 1 2.73368388541751 -1.57600461630951 3.43692921393904e-12 91.8098000344792 69.579377683105 1.31949728628821 0.187693792825313 -503.571873076068 105.091396420349 -4.79175165835517 2.26914200330689e-06 LINC00634 other 2.61825267517876e-08 0.0197574194227931 1 1.31949728628821 -4.79175165835517 0.851166204611141 3.94219486406921 6.95922200255201 0.566470628846669 0.571364032477164 0.0228921053722692 5.07162746386627 0.00451375924895275 0.996400608473189 C17orf107 other 1 1 1 0.566470628846669 0.00451375924895275 0.0412923207949131 -148.765773644849 160.126494050367 -0.929051588415194 0.353376411915474 -800.334044300076 316.427936091918 -2.52927745313735 0.011781242177634 ITSN1 other 1 1 1 -0.929051588415194 -2.52927745313735 8.05432901101741e-05 9.04449640351966 32.566757617589 0.277721734221242 0.78135761598319 -247.964472486482 64.3555706334147 -3.85303820704114 0.000134185986147178 CRYZL1 other 0.403682970032193 1 1 0.277721734221242 -3.85303820704114 0.0010550527546595 -3.19305908044598 70.9967342688722 -0.0449747317722182 0.964148231199911 -514.834053215863 156.006715887228 -3.30007621971878 0.00104669990125027 C5orf51 other 1 1 1 -0.0449747317722182 -3.30007621971878 0.00302332510232632 -15.883615334222 14.9310073901378 -1.06380064781921 0.288009181899162 -71.9472293130324 22.5769854864847 -3.18675092191127 0.00154250142138077 CATSPER2P1 other 1 1 1 -1.06380064781921 -3.18675092191127 4.67178480718309e-51 105.540634573641 6.10581487608988 17.2852660480969 2.43724914998395e-51 -3.40599165601861 30.7796965397053 -0.110657090190118 0.91193930927996 LOH12CR2 other 4.4680949895899e-47 1 2.40117786256418e-47 17.2852660480969 -0.110657090190118 1.71147840689749e-11 43.9611292077806 13.2967294853716 3.30616105683314 0.00102404310987293 -37.4608269180742 15.3097061169333 -2.44686779954846 0.0148042188360351 PLPP6 other 1.28377995301381e-07 1 1 3.30616105683314 -2.44686779954846 0.809119540567263 -7.05245616577308 15.0036819308416 -0.470048365346646 0.638556565697917 -18.013428005603 28.9463327674948 -0.622304322633614 0.534068580750558 GMNC other 1 1 1 -0.470048365346646 -0.622304322633614 0.405796216685206 0.577335022457675 4.01884540333991 0.143656937382531 0.885837901712194 -9.06173867592736 8.37764965677133 -1.08165643673141 0.28000447878764 TTC23L other 1 1 1 0.143656937382531 -1.08165643673141 0.000347831061286543 14.0746251736883 4.24837490859806 3.31294329631864 0.000999950307754311 0.537861587145412 6.80804679759208 0.0790038028727486 0.937065761596627 RFPL3S other 1 1 1 3.31294329631864 0.0790038028727486 0.121562890860352 0.768884264377552 2.51313391153672 0.305946396587915 0.759791488123964 -3.37568663154925 3.09134779274821 -1.09197892241955 0.275445395849386 C1QTNF9B other 1 1 1 0.305946396587915 -1.09197892241955 0.309863714530533 -6.61808964243756 5.60349837721287 -1.18106389917959 0.238219721300056 -9.90244754070851 6.46734948149375 -1.53114464728468 0.126457203514315 KRTAP5-2 other 1 1 1 -1.18106389917959 -1.53114464728468 0.252393272010561 863.530973210144 1108.05458946863 0.779321688134743 0.436214009168255 -2103.43591420706 2213.5506529594 -0.950254249386559 0.342510727546588 OLIG2 other 1 1 1 0.779321688134743 -0.950254249386559 0.475727845195661 -32.468172857675 36.4684900671329 -0.890307572315335 0.373792881202895 -83.6756783764386 72.8527734714378 -1.14855858451626 0.251369224965752 C21orf62 other 1 1 1 -0.890307572315335 -1.14855858451626 6.83508152655172e-06 115.300351462439 54.7012035522356 2.10782110767153 0.0356153854027358 -162.330434264612 81.1377858517743 -2.00067616537088 0.0460454205559437 NYNRIN other 0.0386045404619641 1 1 2.10782110767153 -2.00067616537088 0.157104798855877 -141.173038566927 115.989619349147 -1.21711787105684 0.224214743807927 -337.382276734951 175.279411855683 -1.92482547244474 0.0548985416055546 DOK6 other 1 1 1 -1.21711787105684 -1.92482547244474 0.00980102041753581 19.4887853484672 77.2856287128057 0.252165708852389 0.801031808844245 -258.302722789515 116.874642705423 -2.21008352890159 0.0276181020766755 ZDHHC11B other 1 1 1 0.252165708852389 -2.21008352890159 0.432862829742695 -0.872579873806045 11.0510880937762 -0.0789587293487842 0.93710159231041 -20.2909782323627 18.180971022731 -1.11605580400484 0.265011551611121 CFAP99 other 1 1 1 -0.0789587293487842 -1.11605580400484 0.700076817377415 -48.7226162489539 138.401654591656 -0.352037816258096 0.724979990117701 -191.899948200981 230.611061425389 -0.832136789167279 0.405787275638877 HERC2P9 other 1 1 1 -0.352037816258096 -0.832136789167279 0.00179142103621034 -162.589122039733 88.0051763960826 -1.84749498493103 0.0653542010006824 208.716931093842 149.387570671068 1.39715058057547 0.163080548995725 ATP10A other 1 1 1 -1.84749498493103 1.39715058057547 0.0277503507721285 -11.1947723440134 23.1997174137841 -0.482539168229786 0.629664597310294 -126.245362563237 48.4237813095807 -2.60709426544224 0.0094437475308136 ANKUB1 other 1 1 1 -0.482539168229786 -2.60709426544224 1.17462825481248e-08 26.8520576555518 6.81610731230957 3.93950042527327 9.49937166297546e-05 -17.6449300702092 11.3113162133836 -1.55993606202358 0.119497211049516 TSSK2 other 7.99921841527297e-05 1 0.790252728642928 3.93950042527327 -1.55993606202358 0.842701107645161 27.5160814327265 47.1004776463748 0.584199626154838 0.559387456055375 26.4829328026946 102.736420240494 0.257775506881602 0.796701512989268 HCP5 other 1 1 1 0.584199626154838 0.257775506881602 0.469951960344173 -0.356564254490423 2.81743971819015 -0.1265561254739 0.899349799033247 -7.34218057730045 6.23302681272406 -1.17794785710085 0.239457003806872 HCG27 other 1 1 1 -0.1265561254739 -1.17794785710085 4.21171326683708e-19 167.964630713288 43.1258464688086 3.89475556925637 0.000113640149830111 -318.152878547736 71.2214425391297 -4.46709399873416 1.01046524503756e-05 RAB12 other 3.56942699364443e-15 0.0855965109071318 0.941622281492296 3.89475556925637 -4.46709399873416 1.2989391809047e-05 80.5790932485548 35.6623306631664 2.2595016015535 0.0243428611828938 -111.777343453451 58.8956007153433 -1.89788952138714 0.0583678602194129 TMEM200C other 0.0714156761661404 1 1 2.2595016015535 -1.89788952138714 0.0850301071801907 4912.74627582898 2319.87783806868 2.11767455820815 0.0347654714299475 1114.36873298094 4969.48611734522 0.224242246917929 0.822673376112603 HLA-A other 1 1 1 2.11767455820815 0.224242246917929 0.0267487996608978 -158.598973087821 123.330369432991 -1.28596852354353 0.199133451770402 -645.266516592478 238.78827891243 -2.70225372673804 0.00715466896959965 HACD2 other 1 1 1 -1.28596852354353 -2.70225372673804 0.00292297894569509 115.58924727772 36.1934259148437 3.19365311119428 0.00150621464808005 21.6055968170963 71.8875024058883 0.300547328729097 0.763902303823701 CFAP44 other 1 1 1 3.19365311119428 0.300547328729097 0.218692002902706 -1.28949570244274 20.0651739712529 -0.0642653636739053 0.948788318430615 -61.0917192768959 38.8508298869818 -1.57246883669187 0.116565560669553 LNP1 other 1 1 1 -0.0642653636739053 -1.57246883669187 3.34270650024982e-06 -16.8146497334799 14.767378257559 -1.13863472853571 0.2554894969212 98.1294266097965 25.1251083612228 3.90563197575085 0.000109103122662907 VGLL3 other 0.0194344955924525 0.864751350226202 1 -1.13863472853571 3.90563197575085 0.0905102000240268 -6.90727448006513 6.46806218573669 -1.06790477297775 0.286153035460952 8.88849113025558 10.1795574913179 0.873170679357779 0.383049594419044 PRSS50 other 1 1 1 -1.06790477297775 0.873170679357779 0.322292480369197 8.886016318378 12.2709059371346 0.724153242140572 0.469360040845097 34.3628860540053 22.8057936156289 1.50676124817933 0.132596032942473 TRIM71 other 1 1 1 0.724153242140572 1.50676124817933 0.00150758395135826 2.20912291933425 2.32566149336055 0.949890139059789 0.342691903887892 -11.3843332723614 4.3659645159088 -2.6075185061351 0.00943151825167613 ZCWPW2 other 1 1 1 0.949890139059789 -2.6075185061351 0.00110991044469402 221.824424458401 137.165151981019 1.61720685797145 0.106553560509726 -664.905961875668 285.263116315179 -2.33085149760838 0.0202142455586026 ANKRD28 other 1 1 1 1.61720685797145 -2.33085149760838 0.533481147372635 -3.48065915449554 18.7019561534741 -0.186112036940531 0.852443065520587 -43.5911907389817 40.1443968626796 -1.08585989940495 0.278138234125412 COLQ other 1 1 1 -0.186112036940531 -1.08585989940495 2.61568729603518e-06 18.8968916039939 22.3460477477908 0.845648045563767 0.398210841521509 -205.689299006647 47.9665657291717 -4.28818064999708 2.21778604713987e-05 METTL6 other 0.0153671628642067 0.184320198377795 1 0.845648045563767 -4.28818064999708 2.6590237198043e-06 120.41342193935 30.115389197931 3.9984016526548 7.48619032858225e-05 -103.490240291344 70.1414907126743 -1.47544968377245 0.140811805235224 THUMPD3-AS1 other 0.0156004921640919 1 0.626369544792477 3.9984016526548 -1.47544968377245 4.18569803999844e-05 4.90217921404551 1.40268387611778 3.49485675105449 0.000522637258176652 -3.67959136528148 3.01090953981806 -1.22208632196364 0.222332251299044 SNORA7A other 0.217740012040719 1 1 3.49485675105449 -1.22208632196364 0.263017245149375 0.652740991266323 2.52807982823902 0.25819635281098 0.796377205421024 -4.91895535362591 4.14985148643286 -1.18533286545494 0.236531501234807 MIR130B other 1 1 1 0.25819635281098 -1.18533286545494 0.827052664758606 -3.09874655711497 50.7188344588154 -0.06109656482014 0.951310236663024 -66.5444657112164 112.102529331334 -0.593603606521094 0.553084386321446 MIR219A2 other 1 1 1 -0.06109656482014 -0.593603606521094 0.960865058576029 -436.362274243129 2218.66319198715 -0.196678015761509 0.844170949279937 -1141.08888358066 4273.94405990772 -0.266987323087542 0.789604867238827 GPX3 other 1 1 1 -0.196678015761509 -0.266987323087542 0.574488509984281 -162.20396985821 320.846260262087 -0.505550445642444 0.613427751985245 -346.773579857911 372.098675170987 -0.931939840147405 0.351883374172457 DIO2 other 1 1 1 -0.505550445642444 -0.931939840147405 1.37261487900782e-07 478.29187551871 89.6921037642577 5.33259735746448 1.5577648575293e-07 -50.9454773080013 213.896007403587 -0.238178720240791 0.811854376236474 SELENOH other 0.000876963646198095 1 0.00142083732655247 5.33259735746448 -0.238178720240791 1.19181934121548e-21 8.57739826821985 3.08509116868198 2.78027383932524 0.00566536295766044 -11.7120340059955 3.94218469501658 -2.97095009800048 0.00313217063158759 AKR7L other 1.03390327850442e-17 1 1 2.78027383932524 -2.97095009800048 8.48829038733425e-06 -1.82170497526856 56.366628670343 -0.0323188563559956 0.97423249377017 -346.311318009892 88.7053265365685 -3.90406451936262 0.000109496221786921 SACM1L essential 0.0475514027498465 0.867514612352837 1 -0.0323188563559956 -3.90406451936262 0.121297016329821 -86.3905582968412 244.555793074128 -0.353255006601521 0.724067615763333 -682.373138548546 373.43138291189 -1.82730528223856 0.0683357026161628 SLC48A1 other 1 1 1 -0.353255006601521 -1.82730528223856 0.0303788044556077 184.588786127169 71.0381121942242 2.59844723382412 0.00968041187794836 81.7234450867064 141.600098045481 0.577142574155968 0.564139666079195 LINC01089 other 1 1 1 2.59844723382412 0.577142574155968 0.948423142408399 -1.03245870835093 5.19781104667696 -0.198633366830639 0.842644758499092 -2.77558312114486 8.52837238374227 -0.325452852696252 0.744998901138934 CTAGE1 other 1 1 1 -0.198633366830639 -0.325452852696252 0.0129633411627162 -18.1097183179404 66.5764047232318 -0.272014062538 0.785740860112095 -145.441906660547 49.3931674423296 -2.94457541785231 0.00340816619253829 C17orf51 other 1 1 1 -0.272014062538 -2.94457541785231 0.0166549437216862 115.818745863665 49.7736802867479 2.32690741766391 0.0204306071178905 -65.1440064526814 104.892305936151 -0.621056100075969 0.534889498972567 RNF208 other 1 1 1 2.32690741766391 -0.621056100075969 3.46231568051651e-05 59.7815432852599 13.0453680513636 4.58258770851706 5.99779657902053e-06 41.3377378502517 29.2712952767678 1.41222783137516 0.158592969228759 MAP10 other 0.181840819540727 1 0.0524867178630086 4.58258770851706 1.41222783137516 2.67291186710045e-41 147.138763922254 47.3865659608647 3.10507336707563 0.00202663935058983 -236.874509232971 58.6299614000374 -4.04016143924701 6.31502225745961e-05 ZNF580 other 2.50371654591299e-37 0.509685446399565 1 3.10507336707563 -4.04016143924701 1.51355293896284e-20 10.2725321718785 8.67786805258638 1.18376219938224 0.237156658484296 -64.4280816232964 12.9650801282339 -4.96935468088562 9.69179242777004e-07 ZNF611 other 1.29983926398129e-16 0.0085471917420504 1 1.18376219938224 -4.96935468088562 0.0920301906712287 -61.6826375484692 37.6999397197116 -1.6361468481664 0.102527179179942 -36.1024649814629 46.1090811479969 -0.782979493032714 0.434062287740008 SYT3 other 1 1 1 -1.6361468481664 -0.782979493032714 3.2422750921147e-61 451.349919332541 97.4466395763348 4.6317648437633 4.78717578207433e-06 -562.486485769578 119.012882667352 -4.72626553666261 3.08671097806511e-06 NUP62 other 3.14241301927756e-57 0.0267216569371097 0.0420697007728692 4.6317648437633 -4.72626553666261 1.14264360756075e-10 52.1587008013036 30.8079886676777 1.69302518784766 0.0911617328416968 -110.384821326274 39.4937247002665 -2.79499647511162 0.00541804966145965 FGFR1OP other 8.39500258474881e-07 1 1 1.69302518784766 -2.79499647511162 3.59019565867434e-06 2.85398409741268 4.05633267541931 0.703587285803096 0.48206367590744 -14.0146340326249 5.32830071813575 -2.63022580255723 0.00883341720555912 LPAL2 other 0.0208339054072872 1 1 0.703587285803096 -2.63022580255723 3.31711376773551e-10 230.876414011217 82.195321470023 2.80887537005885 0.00519390847914485 -185.014567982298 107.969790808849 -1.71357716446677 0.0873139654290513 SCAF8 other 2.40324892472438e-06 1 1 2.80887537005885 -1.71357716446677 8.25508665851137e-05 47.1509784165036 20.2329761549029 2.33040251001719 0.0202423714357542 -62.9479653501985 35.2109911282829 -1.7877362531734 0.0745161575594484 TCTEX1D2 other 0.413332188991664 1 1 2.33040251001719 -1.7877362531734 0.864800736274023 15.9753088246421 30.8972051919867 0.517047050870005 0.605384899472483 17.7957565176226 35.8755361136806 0.496041549350853 0.620114481857271 CRIP1 other 1 1 1 0.517047050870005 0.496041549350853 1.34682629282325e-07 31.7473898677251 7.08151173944694 4.48313736329477 9.40462483064533e-06 16.4404200140052 8.22087037268827 1.99983934409479 0.0461346815844371 FAM24B other 0.000861026049001906 1 0.0817544036527999 4.48313736329477 1.99983934409479 0.000607449681093627 227.301348068198 59.1175803972331 3.84490276058113 0.000138564577669116 127.694996882458 134.373019189768 0.950302357217423 0.342485107884833 TRIM59 other 1 1 1 3.84490276058113 0.950302357217423 0.577487834921442 7.93052486647955 34.2366219326569 0.231638649457847 0.816926863008209 -26.7373724475631 48.3816919173251 -0.552634093351924 0.580795900831371 CFAP206 other 1 1 1 0.231638649457847 -0.552634093351924 6.19255174254337e-08 30.5249795249797 6.58973263750826 4.63220303525424 4.78047231937222e-06 -20.3457719082719 13.8861289639842 -1.46518673138077 0.143589057019323 CCDC183 other 0.000403630522578977 1 0.0420155712149624 4.63220303525424 -1.46518673138077 0.0170517955698746 79.7959049959057 30.4470110901663 2.62081242587644 0.00907781204488309 -1.39188165438105 64.1590707579562 -0.0216942302614078 0.982701768217785 DNLZ essential 1 1 1 2.62081242587644 -0.0216942302614078 1.22941495322106e-51 221.283934544437 77.0489427419545 2.87199183622209 0.00427695200624149 -673.40147815811 98.4641597569521 -6.83905168967396 2.69102944845885e-11 NRAS og 1.17716481770916e-47 2.55943810842921e-07 1 2.87199183622209 -6.83905168967396 0.287869814818549 -1.61856525142572 16.3882469764913 -0.0987637819803138 0.921371215958563 43.8605229805792 32.2379271916578 1.36052553006352 0.174366598455602 LTC4S other 1 1 1 -0.0987637819803138 1.36052553006352 8.25378331717326e-17 32.2733901181084 34.7279325657138 0.929320801261036 0.353235900756948 -177.764415996055 41.8853109864835 -4.24407535265574 2.68217204762441e-05 CHUK other 6.82010115498027e-13 0.222244775866159 1 0.929320801261036 -4.24407535265574 7.96104332476184e-05 459.994564560939 114.539049555578 4.01605012740858 6.96335179723626e-05 71.4131192518068 219.658863107085 0.325109209078408 0.745253652522388 MXD3 other 0.399405543603301 1 0.583459247090427 4.01605012740858 0.325109209078408 5.65600355785295e-20 114.610889509376 191.187603361266 0.599468205544733 0.549170664464331 -1289.67399282011 254.276223041429 -5.07194096795272 5.82562891520026e-07 GSTM2 other 4.8307926387622e-16 0.00517665385404695 1 0.599468205544733 -5.07194096795272 2.28196206287309e-11 199.622505083978 38.5855015793683 5.17351069477134 3.510654090298e-07 -254.601005318899 89.0572118337303 -2.85884770111867 0.00445572269554832 COG8 essential 1.70508205337877e-07 1 0.00318240793285514 5.17351069477134 -2.85884770111867 4.33063574678639e-12 264.048136886834 42.5621622376719 6.20382337279668 1.27731350925088e-09 129.944698336319 53.7783978233843 2.41629917579686 0.0160871718452943 ARHGAP19 other 3.29158415193073e-08 1 1.20310159436341e-05 6.20382337279668 2.41629917579686 0.5071123389649 4.60352932358292 162.778453026304 0.0282809501994654 0.977450955047692 -406.028358086423 375.687902809239 -1.08075973447724 0.280398715234286 LCAT other 1 1 1 0.0282809501994654 -1.08075973447724 1.00504660026925e-13 -0.21431508753874 2.11642054843583 -0.10126299694885 0.919388027132266 -14.039078175934 2.75700334192715 -5.09215130879045 5.26868623351056e-07 HNRNPA1P33 other 7.91373693052008e-10 0.00469071135369445 1 -0.10126299694885 -5.09215130879045 1.91122266868545e-05 109.141138604112 31.57768381802 3.45627434973018 0.000601149068156777 -170.406959748728 70.9328060561739 -2.40237161368997 0.0167044591294993 KRT222 other 0.103225136335701 1 1 3.45627434973018 -2.40237161368997 1.74797502210091e-27 -80.9713469510466 68.2912448932903 -1.18567683277073 0.236392780238425 -564.676101826305 77.8647162544346 -7.25201514869895 1.87540041288791e-12 SYNJ2BP other 1.56723440481567e-23 1.80057193641368e-08 1 -1.18567683277073 -7.25201514869895 1.20163591946525e-09 9.88686462109078 1.95221515305291 5.06443391018122 6.04667341929383e-07 -3.17239526258112 3.71541999535849 -0.853845666585273 0.393657233447324 TTLL13P other 8.53161502820328e-06 1 0.00545168075483532 5.06443391018122 -0.853845666585273 1.84341605803791e-09 3.02659995096467 4.14204344835286 0.73070212534063 0.465351792223561 -15.2413471599208 5.34438287455268 -2.85184417315844 0.0045522539916365 GBP7 other 1.29868661288771e-05 1 1 0.73070212534063 -2.85184417315844 5.62757803581023e-25 21.3141750147623 47.4617672476484 0.449080939265243 0.653595384522708 -347.904453583897 61.2388207021841 -5.68110962286197 2.44324238396092e-08 RBMXL1 other 4.98040656169205e-21 0.000224387380542971 1 0.449080939265243 -5.68110962286197 0.00121787984059179 145.97485514443 55.4484575815876 2.63262246618206 0.00877370091128772 -175.321978443784 117.218061215682 -1.49569082294571 0.135457697552596 SRA1 other 1 1 1 2.63262246618206 -1.49569082294571 2.77699507424372e-05 58.9506196262418 50.2030737479562 1.17424323303793 0.240935658593416 -224.390181992748 77.4348314831245 -2.89779389578255 0.00394652987086899 TMEM110 other 0.147541748294569 1 1 1.17424323303793 -2.89779389578255 2.37021650125788e-14 222.55237898952 50.8848989252123 4.37364294103471 1.52858985812848e-05 -36.2723766340828 61.6875638787287 -0.588001443944042 0.556834365247389 DNAJC9 essential 1.8869293566514e-10 1 0.131779731669256 4.37364294103471 -0.588001443944042 3.84523641692335e-20 196.037787837039 21.3542067263996 9.18028894019666 1.78196621815626e-18 -10.3924424325923 57.9337450674601 -0.179384958118812 0.857719352130797 C8orf82 other 3.29036880196131e-16 1 1.7390208322987e-14 9.18028894019666 -0.179384958118812 0.956019008586809 -10.0665499124344 38.5249408005134 -0.261299555645268 0.793985176712938 -1.9439579684769 66.8447358058257 -0.0290816912512575 0.976812775211709 CPLX3 other 1 1 1 -0.261299555645268 -0.0290816912512575 0.00393270710391577 36.4102560469305 17.7327659525294 2.05327562233668 0.0406405557578893 -69.1859776401739 41.6333712698901 -1.6617913834475 0.097271745233026 ZBTB9 other 1 1 1 2.05327562233668 -1.6617913834475 0.00226327506680976 573.688055929365 184.18926556324 3.11466607011575 0.00196300000102034 -232.226244789443 439.251024974576 -0.528686859189195 0.597291713119868 TMX2 essential 1 1 1 3.11466607011575 -0.528686859189195 3.81545221968892e-05 -0.590065485712653 127.766113163663 -0.00461832540023194 0.996317230044174 -829.657210972632 221.666115537665 -3.74282379135957 0.000206262756276729 HEXA other 0.199281069434352 1 1 -0.00461832540023194 -3.74282379135957 6.83704026954015e-13 661.229663105999 151.350429757306 4.36886544799572 1.56253002501988e-05 -584.351684470008 197.372262541781 -2.96065757642268 0.00323737278957438 NDUFS3 other 5.28434842432758e-09 1 0.134674462856464 4.36886544799572 -2.96065757642268 7.5522133633201e-49 -89.4434804503921 83.3331541270227 -1.07332407356207 0.283716709038198 -1069.09722078438 107.014150939462 -9.99024158393 2.62099705002987e-21 LEPROT other 7.19423844989872e-45 2.57434330253933e-17 1 -1.07332407356207 -9.99024158393 0.0930944273649065 87.1672268907567 60.1886904621106 1.44823265336915 0.148267441344129 289.89482870071 140.289875805074 2.06639878349814 0.039378121545233 GPSM3 other 1 1 1 1.44823265336915 2.06639878349814 4.82584309059552e-05 57.7307965860587 85.747828713119 0.673262489003715 0.501137842053971 -412.292940967283 133.491803093809 -3.08852627211538 0.00214036615724349 NCKIPSD other 0.248482660734763 1 1 0.673262489003715 -3.08852627211538 9.98312471837732e-06 68.4670150228626 99.7719412784847 0.686235169382507 0.492930424113618 -936.424885695618 225.372071040502 -4.15501744014825 3.91739355413944e-05 ATF6B other 0.0555061734341779 0.32097282280971 1 0.686235169382507 -4.15501744014825 0.00385422889331406 91.1608108108103 41.6834385826886 2.18697914352656 0.029275908149414 -42.0577702702702 64.8925746466374 -0.648113755684519 0.517253320704497 TREX1 other 1 1 1 2.18697914352656 -0.648113755684519 0.625510299841044 -1.73564075786959 2.58187604802384 -0.672240156222078 0.501790192303185 -3.24367414979664 3.38181170138551 -0.959152796256433 0.338018271001084 SEC14L1P1 other 1 1 1 -0.672240156222078 -0.959152796256433 0.787300348797069 -66.6305938690892 207.940416539572 -0.320431183980094 0.748794301607357 -308.544475544918 446.816220035638 -0.690540006628024 0.490220421665475 S1PR3 other 1 1 1 -0.320431183980094 -0.690540006628024 0.000196296339422567 243.806356522495 209.40284327439 1.16429343895309 0.244938896205932 1964.26909364766 472.894868398982 4.15371200854396 3.93407438043868e-05 CLIC1 other 0.935548353687956 0.322279373245537 1 1.16429343895309 4.15371200854396 2.17199745560286e-15 1550.58135385589 184.582944104026 8.40045845721276 6.25676526310471e-16 685.037248329736 416.844039440247 1.64338981372896 0.101019906346956 DDAH2 other 1.75736314132827e-11 1 6.07469339394836e-12 8.40045845721276 1.64338981372896 4.57719226713961e-05 -576.364039978961 288.26435250418 -1.99942877075168 0.0461792244072577 -2858.12286766362 633.265594249254 -4.51330830794932 8.21208332315878e-06 ATP6V1G2 other 0.236686612133789 0.0698437686634654 1 -1.99942877075168 -4.51330830794932 1.67155122600533e-58 144.761613550873 31.0246388307588 4.66602091133295 4.08919560358241e-06 -167.67896060739 38.9129579871268 -4.30907772837166 2.02697597685595e-05 ZNF134 other 1.61488563944375e-54 0.168806559352563 0.0360421700499754 4.66602091133295 -4.30907772837166 2.78172963029651e-06 123.221315097318 31.7871212340483 3.8764540579199 0.000122223696363866 -112.086120087171 69.8306607906393 -1.60511326712515 0.109189609671496 GTF2H4 essential 0.0162814635261255 1 1 3.8764540579199 -1.60511326712515 4.00206921618472e-22 406.422677145392 39.3067358293397 10.3397717610025 1.54194275041721e-22 73.5283179110152 111.786034757643 0.657759424694039 0.511043056584555 DDX47 other 3.48580228729689e-18 1 1.51110389540886e-18 10.3397717610025 0.657759424694039 7.20648522982297e-26 18.3130943214813 7.86237700697845 2.32920582480681 0.0203073490582368 -47.2441983019297 10.8937673326547 -4.33680992619628 1.80025589005764e-05 ZNF845 other 6.4072860178356e-22 0.150411379614316 1 2.32920582480681 -4.33680992619628 9.48146334624812e-38 5.99637177095515 1.34218700859237 4.46761273396911 1.01087158108531e-05 -9.09073339235463 2.0052807910911 -4.53339673563035 7.52158756050334e-06 ZNF321P other 8.804486863326e-34 0.0640775501642257 0.0877941968172594 4.46761273396911 -4.53339673563035 0.0223201310403088 15.2352578043589 26.7492630468517 0.569558038951358 0.569269477187987 53.7560146798966 19.9951110728874 2.68845791773509 0.00745201776586507 KCTD11 other 1 1 1 0.569558038951358 2.68845791773509 0.0363367986949542 100.293381218544 39.372045275497 2.5473246440911 0.0111960766553498 52.8213746764801 84.3401446392356 0.626289827962984 0.531451104726538 UBD other 1 1 1 2.5473246440911 0.626289827962984 0.00519638481237735 -19.5488700124872 9.28036333871401 -2.10647679395666 0.035733835801636 -34.4252503784454 11.3857194835152 -3.02354633172616 0.00264575348587835 PPM1N other 1 1 1 -2.10647679395666 -3.02354633172616 0.0867815404086576 30.8453779765003 16.6093116730672 1.85711356278042 0.0639660580007032 52.506036763602 24.6340542961884 2.13144113966356 0.0336089003968379 LTB4R other 1 1 1 1.85711356278042 2.13144113966356 2.19032645593465e-06 22.4429210178406 6.29407322104793 3.56572289988452 0.000402818984065159 -4.74215138205983 9.33503714804142 -0.507994912805974 0.611712636738789 LTB4R2 other 0.012938258375206 1 1 3.56572289988452 -0.507994912805974 1.59387702178894e-09 81.4336962818822 21.2072049706343 3.83990706906657 0.0001412326295479 -46.0677751534568 31.4534069201754 -1.46463546128312 0.143737779755147 MDP1 other 1.12543656508517e-05 1 1 3.83990706906657 -1.46463546128312 0.0404896589518823 280.12387290364 276.5225955059 1.01302344711163 0.311608230948518 -450.702560446036 410.123716496997 -1.09894293433122 0.272396644312075 IRF9 other 1 1 1 1.01302344711163 -1.09894293433122 0.0197477889198589 68.4720638406695 33.9108752873571 2.01917713006358 0.0440845181418647 -17.6958683141481 39.537549578213 -0.447571195051991 0.65468651812917 GALT other 1 1 1 2.01917713006358 -0.447571195051991 2.18130443289749e-47 84.6639538886587 13.4960548058485 6.27323726130465 8.51498709626472e-10 -47.1467243646891 17.4500048554683 -2.70181726338688 0.00716452806586994 NUDT19 other 2.07136668947945e-43 1 8.03559332274502e-06 6.27323726130465 -2.70181726338688 0.00206136161135121 148.581235401436 128.212462218924 1.15886734276838 0.247141682012371 -318.737280244081 93.4365715536826 -3.4112690025335 0.000706608170660144 TAX1BP3 other 1 1 1 1.15886734276838 -3.4112690025335 0.302007819678441 69.8612264421706 57.2558599570211 1.22015853913663 0.223061314704244 4.54374124870641 86.0140250241459 0.0528255856812989 0.957894959609162 AP1G2 other 1 1 1 1.22015853913663 0.0528255856812989 3.13623184078244e-19 284.137768394169 94.7617373688665 2.9984440585776 0.00286851163679269 -662.098463651399 129.721625490442 -5.10399450475729 4.97103208039164e-07 NAXD other 2.6610927169039e-15 0.00443068089325307 1 2.9984440585776 -5.10399450475729 2.01747672392955e-05 15.2375249391294 37.7967589525389 0.403143691718729 0.687040589976862 -194.197350269039 57.6734870049483 -3.36718586570598 0.000826895034443146 GANC other 0.108741995419803 1 1 0.403143691718729 -3.36718586570598 0.0326519732023656 224.778907804554 111.980483515537 2.00730431542892 0.0453311214772654 -213.174662834402 262.844548315298 -0.811029424809246 0.417789249554229 TTLL3 other 1 1 1 2.00730431542892 -0.811029424809246 0.000208196899274616 101.491443715597 25.4229714373555 3.99211571179559 7.68300453260342e-05 9.35921044742113 45.6024890109453 0.205234640705133 0.837484588820861 ZNF891 other 0.987477893259503 1 0.642529669061624 3.99211571179559 0.205234640705133 1.64619612233612e-07 89.3828830446754 39.7778858242225 2.24704961544855 0.0251340306206356 -61.2366539677523 46.1669900242119 -1.32641642731392 0.185392988470203 TSPAN4 other 0.00104813307109141 1 1 2.24704961544855 -1.32641642731392 1.1553486866841e-11 240.192308366273 33.2487908725366 7.22409152522509 2.2682906636936e-12 31.6188002693553 87.6806142548126 0.360613352655884 0.718563149911841 ARL16 other 8.70208630810463e-08 1 2.18096147314139e-08 7.22409152522509 0.360613352655884 5.67016412009172e-15 190.525519865305 32.3471101245233 5.89003218933186 7.71256716100307e-09 -118.164638226227 55.8102802850893 -2.11725577478952 0.0348024734282908 LYRM4 essential 4.55427582125767e-11 1 7.19042636420316e-05 5.89003218933186 -2.11725577478952 5.20780165728178e-32 39.7025445633499 13.8900440356862 2.85834547834021 0.00446170708187435 -78.6238873390877 17.8361698835614 -4.40811496259357 1.31324585315859e-05 MYCBP other 4.7479527709438e-28 0.110522771001827 1 2.85834547834021 -4.40811496259357 3.94071902850751e-07 23.2931251871581 12.9930084908214 1.79274301279899 0.0737039383734945 -21.3996201673785 16.6842888435378 -1.28262105553676 0.200303219789734 SH3D21 other 0.00245309759524593 1 1 1.79274301279899 -1.28262105553676 0.0151118298325305 0.275223838836058 1.98261746002316 0.138818427853875 0.889657725908033 -8.26036653609401 3.47214916557096 -2.37903561805521 0.0177875625155277 TTC41P other 1 1 1 0.138818427853875 -2.37903561805521 2.29134759786909e-06 -260.764424355242 328.960231681405 -0.792692852331736 0.428389897473049 -2626.215312277 566.995020763076 -4.63181371283044 4.79799281331247e-06 SNURF other 0.0135029113942425 0.0412339502376074 1 -0.792692852331736 -4.63181371283044 0.150019324412832 25.2672627715691 17.2351234523193 1.46603317588473 0.143358417894661 46.5712354432896 23.9569525624384 1.9439549050286 0.0525423513366154 ANG other 1 1 1 1.46603317588473 1.9439549050286 9.41626758297346e-05 25.8015444519854 21.8012390000906 1.1834898214674 0.237273531010148 -25.1736159432444 24.7388101606269 -1.01757585671236 0.30945577070814 SCART1 other 0.46835017943021 1 1 1.1834898214674 -1.01757585671236 3.46207871261243e-10 -220.786747298477 271.827041944774 -0.812232461196165 0.417099474573065 -1674.20278074763 349.686490535764 -4.78772507963503 2.31120035906204e-06 SOGA3 other 2.50585257218887e-06 0.0201120655245578 1 -0.812232461196165 -4.78772507963503 0.680709568492225 0.0169417694735453 12.4947088304361 0.00135591550819308 0.99891875360791 -24.6679708769583 29.8201954462523 -0.827223648531065 0.408560753168118 VAC14-AS1 other 1 1 1 0.00135591550819308 -0.827223648531065 0.303380416399094 197.950566114039 130.895303294696 1.51228165664872 0.131185035476535 111.448948645377 245.313085040626 0.454313102079003 0.649829055428687 NEURL1B other 1 1 1 1.51228165664872 0.454313102079003 6.80903266003287e-06 33.8177185185199 22.842367886327 1.48048217622668 0.139465196845387 -112.806518518517 37.1441820335522 -3.03699024564922 0.00253258008988866 HAUS3 essential 0.0384642254965257 1 1 1.48048217622668 -3.03699024564922 0.263058657848107 -56.7387105381989 89.8282467611364 -0.631635510922012 0.527956098640542 -309.795778767603 189.292710232832 -1.63659645628483 0.10243638938255 LCNL1 other 1 1 1 -0.631635510922012 -1.63659645628483 3.35348817814067e-45 88.2578166411648 58.6848136217585 1.50392940173608 0.133323544519334 -515.304764733227 69.9233882916768 -7.36956227841387 8.65884548129355e-13 BBIP1 other 3.17038772361419e-41 8.32721169936001e-09 1 1.50392940173608 -7.36956227841387 7.94388608234873e-07 24.2200890257088 44.8246304879197 0.540329920449342 0.589244790787639 -132.136619796434 53.4171165244687 -2.47367563795598 0.0137521460334864 AS3MT other 0.00484894806466567 1 1 0.540329920449342 -2.47367563795598 0.0287092522609885 -33.4626598400967 13.8724328502129 -2.41216953085364 0.0162699598926022 -10.9183207647103 22.0565068949057 -0.495015861610983 0.620838287442063 SEC14L6 other 1 1 1 -2.41216953085364 -0.495015861610983 0.000257164500924863 771.263027525449 458.87075959744 1.68078486457073 0.0935176376649852 -492.757034127174 543.198287344709 -0.907140257263872 0.364831426494473 MEG3 other 1 1 1 1.68078486457073 -0.907140257263872 1.4753579761053e-21 32.7270197277345 23.2597036909581 1.40702651085176 0.160130328788147 -132.908602607513 27.9651025286251 -4.75265922846047 2.72892465130731e-06 NUTM2D other 1.27839768629525e-17 0.023673421350091 1 1.40702651085176 -4.75265922846047 0.0111440267710335 -40.2554687148415 43.9502905242234 -0.915931800101628 0.360208976891946 -253.1021046789 86.1681361841603 -2.93730508616276 0.00348624517663249 CPEB1 other 1 1 1 -0.915931800101628 -2.93730508616276 2.74943980167814e-18 294.340937463199 170.900539854727 1.72229378393656 0.0857222442345639 -848.241490990461 207.182055813698 -4.09418415923634 5.04575429906169e-05 ZSWIM8 other 2.3089795454493e-14 0.410724399943622 1 1.72229378393656 -4.09418415923634 3.12224354453411e-14 -101.339441781791 104.929732647247 -0.965783855777784 0.334685284793844 516.07075656751 127.404696173322 4.05064155457383 6.04174208042714e-05 C10orf105 other 2.48155916919571e-10 0.488535264623338 1 -0.965783855777784 4.05064155457383 3.31296543722958e-06 133.766776092579 44.6377285911697 2.99672004634754 0.00288517451314309 -99.2045897750965 67.5588774362905 -1.4684167875443 0.142713769823368 IFRD2 other 0.01926489401749 1 1 2.99672004634754 -1.4684167875443 5.7119233879727e-11 506.1406162465 79.9856254544629 6.32789471071467 6.15098415683673e-10 -85.5304747540066 186.433254736812 -0.458772630852528 0.646625016347066 TOMM6 other 4.22910807645499e-07 1 5.81021963454797e-06 6.32789471071467 -0.458772630852528 0.227086923936194 7.94990618018001 4.64617989088471 1.71106293059742 0.0877775046435631 3.87826820999123 11.167976723732 0.347266860052626 0.728557644552665 MS4A4E other 1 1 1 1.71106293059742 0.347266860052626 0.422894260958792 -3.64482487742777 4.52829716189408 -0.804899666943064 0.421317284913689 6.70538866466209 9.2000675295691 0.72884124416597 0.466490983469995 LINC01347 other 1 1 1 -0.804899666943064 0.72884124416597 0.00467528581160067 -40.5233520339414 28.951060096247 -1.39971910870354 0.162308552757921 -97.0543654358215 36.1084230227091 -2.68785943309634 0.00746643269316716 APOC1P1 other 1 1 1 -1.39971910870354 -2.68785943309634 0.297380720600973 3.42852922834541 4.96464851967517 0.69058851090021 0.490191638227803 -13.0023303902583 11.8395984925467 -1.09820703788591 0.272720187720203 SMTNL1 other 1 1 1 0.69058851090021 -1.09820703788591 0.340409352886181 4.24937403576226 6.54259123914019 0.649494043023954 0.516359544770901 20.5815018083413 14.0150984680466 1.46852352520145 0.142679859652193 HLA-F-AS1 other 1 1 1 0.649494043023954 1.46852352520145 0.0010918950325521 114.130550091318 30.9169293720741 3.69152281320689 0.000251105016606867 -16.0396728467877 22.9590843415813 -0.698619884319088 0.485161227263555 ZSWIM7 other 1 1 1 3.69152281320689 -0.698619884319088 0.000341603186422174 233.001274296591 69.2374848732674 3.36524752051692 0.00083209988749291 -121.080331656925 51.7551155717272 -2.33948529182822 0.019758820450463 NEURL4 other 1 1 1 3.36524752051692 -2.33948529182822 0.00100334133587774 20.4311823206924 7.88612642140085 2.59077539833087 0.00989547635309551 15.39159983689 5.89489039210375 2.61100695909583 0.00933733880434987 ALOX12-AS1 other 1 1 1 2.59077539833087 2.61100695909583 0.993599121297379 -7.27601138925149 84.7849612685878 -0.0858172402320504 0.931651185850902 1.79659508838527 99.7913489160582 0.0180035154139114 0.985644303519432 MSMP other 1 1 1 -0.0858172402320504 0.0180035154139114 0.335090456409711 10.9810089908223 11.4957294915289 0.955225068484265 0.339995641495366 -6.16861374355906 13.4316619088774 -0.459259158353444 0.646278012056492 FAM166B other 1 1 1 0.955225068484265 -0.459259158353444 3.21804384555465e-13 186.439582055523 98.9527877046906 1.88412662624446 0.060209897338248 -818.739735702472 162.787800212388 -5.02949075197448 7.18688197551503e-07 PEX26 other 2.50589074253341e-09 0.00636973349489897 1 1.88412662624446 -5.02949075197448 0.773141928289695 1.73451806830927 63.0039131627867 0.0275303228202303 0.97804935123562 -56.7153068639759 103.290895022771 -0.549083313214321 0.583229364998385 C5orf49 other 1 1 1 0.0275303228202303 -0.549083313214321 0.570143804869409 -129.740461198874 132.355532189838 -0.98024207263801 0.327510241434112 -198.925261166324 214.571650519273 -0.927080817456157 0.354397475341975 UBE2QL1 other 1 1 1 -0.98024207263801 -0.927080817456157 1.45577897075866e-06 67.1502547572007 58.3262238181812 1.15128754034423 0.250242038498675 -270.758425473411 86.5063762250047 -3.12992448983371 0.00186543761255548 DHRS4-AS1 other 0.00870555824513677 1 1 1.15128754034423 -3.12992448983371 3.62991892695826e-22 48.930663672654 14.2289237240523 3.43881692119429 0.000640310269219267 -113.97132520673 21.2196767464066 -5.37102080153178 1.27495810307983e-07 HOMEZ other 3.16274836105873e-18 0.00115421957071817 1 3.43881692119429 -5.37102080153178 1.44275910350659e-12 2.63585329341315 1.01753985906738 2.59041773147738 0.00990634264743122 -5.76160179640722 1.51746311279296 -3.79686448246028 0.000167250225719111 RNF212B other 1.10702906012061e-08 1 1 2.59041773147738 -3.79686448246028 0.00038997017756861 241.369919184682 88.0721453606925 2.74059316025709 0.00638713162245305 -96.6826943747756 136.95562226383 -0.705941769871463 0.480604864975054 MYL5 other 1 1 1 2.74059316025709 -0.705941769871463 5.09674644223267e-10 -23.3070928005997 22.1466193659427 -1.05239957464757 0.293200502414015 -182.889736857691 33.0096639840647 -5.54049071647565 5.23313106084403e-08 ZNF407 other 3.67373483556131e-06 0.000477732534544452 1 -1.05239957464757 -5.54049071647565 2.27672655080302e-05 158.821483345789 51.5830221434179 3.07894878481941 0.00220823334822001 -153.67078925636 98.180597712494 -1.56518490248308 0.118263382909742 MCM3AP-AS1 other 0.121873172264486 1 1 3.07894878481941 -1.56518490248308 0.0408851809670015 3.88159558569953 2.12013222671303 1.830827123324 0.0678055687169475 -2.86948417716312 4.16620393687663 -0.688752692052407 0.49134356622457 AATBC other 1 1 1 1.830827123324 -0.688752692052407 0.87071845499212 -1.42931968565458 13.8987734944542 -0.102837828548317 0.918138747432649 -9.98565987957702 21.7977707865868 -0.45810463727427 0.64710445635439 SKOR2 other 1 1 1 -0.102837828548317 -0.45810463727427 0.768499979824941 -4.72899873613266 11.1976524186863 -0.422320550711243 0.672998763214413 -9.37683037367081 13.4050191278854 -0.699501454210156 0.484610865607128 SIAH3 other 1 1 1 -0.422320550711243 -0.699501454210156 0.264996495825097 49.12141538444 36.6418108784703 1.34058372680763 0.180753717021162 0.659409962536146 58.2064291151352 0.0113288166369354 0.990966287264114 HMX1 other 1 1 1 1.34058372680763 0.0113288166369354 4.92246703265009e-13 -0.0384343715977804 8.98225932206121 -0.00427892028271575 0.996587874126095 -47.5170530284928 11.4772767158485 -4.14009823104452 4.16557898561117e-05 RSC1A1 other 3.81835767722668e-09 0.340827672602706 1 -0.00427892028271575 -4.14009823104452 1.01629581347187e-16 -34.7554644008217 36.9899197699151 -0.939592857108312 0.347945489641391 -289.23598007618 47.111034586584 -6.13945294588259 1.86098768998113e-09 TMEM242 other 8.38850564439684e-13 1.7357432184454e-05 1 -0.939592857108312 -6.13945294588259 6.09520722254103e-91 204.094631893615 58.5539050522259 3.4855853202545 0.000540693289142247 -837.819996609307 75.5784678183442 -11.0854324094402 2.4693952984232e-25 TMEM167B other 5.99707438625812e-87 2.42889721552906e-21 1 3.4855853202545 -11.0854324094402 2.12580898622894e-09 -8.85662651852861 16.5963640135804 -0.533648605880268 0.593855375569183 -81.2640903359058 21.2178697367977 -3.82998346883859 0.000146857534355311 TNFRSF25 other 1.49486887911619e-05 1 1 -0.533648605880268 -3.82998346883859 2.42301882731949e-12 33.695064213772 22.7068617528351 1.48391550450889 0.138550575014897 -77.5024410112869 29.0133819145995 -2.67126532299525 0.00783812141141008 SLC35E2 other 1.85118638407209e-08 1 1 1.48391550450889 -2.67126532299525 2.60410533529313e-13 12.9644832857886 3.9614481429122 3.27266262691955 0.00114973775789349 -5.43403801128112 5.08688538930253 -1.06824463210998 0.28599857078345 LINC01356 other 2.03328544579688e-09 1 1 3.27266262691955 -1.06824463210998 8.10129404880883e-37 54.1734779113933 15.8040323033449 3.42782632125647 0.000665950239817415 -91.1475183042897 20.2939173039006 -4.49137132764264 9.06364473724891e-06 CYB5RL other 7.5050388068165e-33 0.0769231528850315 1 3.42782632125647 -4.49137132764264 1.02168411467899e-41 8.98606637046805 8.69812892541437 1.03310337746459 0.302125606824511 -80.3731398167954 11.1136141438593 -7.23195342004961 2.14030870909039e-12 C1orf167 other 9.58033194334493e-38 2.05341217550132e-08 1 1.03310337746459 -7.23195342004961 0.00949736885498506 -0.944402543587142 17.2235862095876 -0.0548319340754619 0.956297360438651 -36.7736808701785 22.0064804403594 -1.67103871833755 0.0954283273821731 TTC34 other 1 1 1 -0.0548319340754619 -1.67103871833755 9.80013493902879e-06 3.8427003317748 3.86770578119697 0.993534810857708 0.320997944284384 -9.73086696164883 5.12952557935716 -1.89703059495579 0.0584814290529497 MMP23A other 0.0545475510706342 1 1 0.993534810857708 -1.89703059495579 1.42425231609445e-09 17.2699285719926 10.7455172250452 1.60717517922177 0.108738198011985 -32.6776446189389 14.2586157081806 -2.29178240635175 0.0223929795601142 ATAD3C other 1.0073736631736e-05 1 1 1.60717517922177 -2.29178240635175 0.0795740637024703 -18.1061810347338 12.010171971788 -1.50757050584 0.132388699491044 -47.5457827466739 21.4624096550744 -2.21530496858411 0.0272551686138924 LY86-AS1 other 1 1 1 -1.50757050584 -2.21530496858411 2.02890255194098e-05 101.098212851621 21.7217277344573 4.65424362589943 4.31553896799169e-06 115.282867004321 50.1331115158887 2.29953544710235 0.0219441533125161 CKLF other 0.1093375585241 1 0.0380112672300708 4.65424362589943 2.29953544710235 0.00413689344035665 328.024938753944 98.540583570088 3.3288308925087 0.000945784604570522 294.599813726591 129.772331692485 2.2701280764893 0.0236848989859167 TENM3 other 1 1 1 3.3288308925087 2.2701280764893 4.67746070897778e-45 52.5067633859227 11.5937920777753 4.52886881476643 7.66385868150319e-06 -66.1163983368405 14.898415649471 -4.43781405301227 1.15250918238736e-05 LINC00339 other 4.4211358621258e-41 0.0972833000853167 0.0668365115613893 4.52886881476643 -4.43781405301227 7.11983196887143e-23 62.660390684467 31.3590612604138 1.99815900623168 0.0463229102757127 -117.080010539257 38.8258091070599 -3.01552017155434 0.00271600104624702 ZNF579 other 6.22842900636873e-19 1 1 1.99815900623168 -3.01552017155434 0.0564117638646007 336.784156812109 140.00698751543 2.40548106054345 0.0165648634230722 -13.3065787685196 104.655416541685 -0.127146584555606 0.898882731273877 RNASEK other 1 1 1 2.40548106054345 -0.127146584555606 5.12694565485247e-09 30.8229812964841 168.941254370972 0.182447924938459 0.855315824558985 -1141.31657778111 248.098725878463 -4.60025166892718 5.53583853643105e-06 FAM19A5 other 3.54682100402694e-05 0.0474310645801413 1 0.182447924938459 -4.60025166892718 0.849233328691708 -6.63510375440075 16.5284596732253 -0.401435093504149 0.68829604698989 -15.8494128965956 28.5174769397454 -0.555778932690429 0.578646413558163 PPP1R3G other 1 1 1 -0.401435093504149 -0.555778932690429 9.56671415341064e-05 -0.474210639388973 3.22435658740262 -0.147071400614215 0.883143334716167 -10.3592959513216 2.39313882368312 -4.32874844066852 1.86006317293915e-05 LINC02076 other 0.475370026282975 0.15529667430869 1 -0.147071400614215 -4.32874844066852 0.0387230040754631 -93.434675454938 362.166555924856 -0.257988138127046 0.796537235052917 -715.186593732964 282.321445586397 -2.53323509394578 0.0116493902432402 VAMP2 other 1 1 1 -0.257988138127046 -2.53323509394578 0.000347837702258143 97.8605055684823 75.2022248807507 1.30129800978177 0.193845263702963 -238.668839090068 113.712323309512 -2.09888279602237 0.0364031094199308 MIR1282 other 1 1 1 1.30129800978177 -2.09888279602237 9.01195775945186e-14 -125.87357201743 89.0183620894802 -1.41401806394622 0.15806698282579 -627.399570133084 107.916612074742 -5.81374413142762 1.17850124963168e-08 PPP3CB-AS1 other 7.09962032289617e-10 0.000108740310303515 1 -1.41401806394622 -5.81374413142762 1.81248556799328e-06 70.0937696664576 13.6541703700037 5.13350630371829 4.285081334449e-07 32.6854415775115 33.9913659120418 0.961580704408596 0.336790806289987 C6orf226 other 0.0107667008631817 1 0.00387542755887568 5.13350630371829 0.961580704408596 5.29579795623155e-11 223.738577991775 31.7636605583427 7.04385370133323 7.35268311629383e-12 123.32639928972 37.0685676099907 3.32698043763853 0.000952452985493827 FANCG other 3.92683418454569e-07 1 7.05122310852578e-08 7.04385370133323 3.32698043763853 1.23587536607795e-38 3.4852894678597 1.10287563965498 3.16018356244594 0.00168731232509721 -9.76384497423088 1.6477400846562 -5.92559777185254 6.3548396698446e-09 ZNF816-ZNF321P other 1.14973485306231e-34 5.88394605030912e-05 1 3.16018356244594 -5.92559777185254 1.80924101623721e-08 14.6466611018363 5.68920712039421 2.57446438350471 0.0103684855390099 -26.0835559265441 9.06010516756299 -2.87894626432467 0.00418640753055446 ARIH2OS other 0.000122015214135038 1 1 2.57446438350471 -2.87894626432467 0.00051882958633675 66.7094064608491 19.8563865250917 3.35959447488349 0.000849192182981122 -2.31307400581796 36.4385646471819 -0.0634787354610261 0.949414383365864 ZBED8 other 1 1 1 3.35959447488349 -0.0634787354610261 0.270630128608572 6.49303193912103 7.07428349538782 0.917835982026202 0.359209864675844 -4.59775538604732 11.16455183295 -0.411817281592794 0.680674807643703 HMSD other 1 1 1 0.917835982026202 -0.411817281592794 0.363875389852081 242.476141954957 821.315326665907 0.295229047945907 0.767959127389123 -1180.45237517913 1285.52936031888 -0.918261699512109 0.358988403982274 NPTXR other 1 1 1 0.295229047945907 -0.918261699512109 9.68784794153919e-07 8.80493390358834 3.81060102339053 2.31064177266032 0.02131638617623 -0.816689675066492 4.64758371480492 -0.175723499603659 0.860592382859022 C19orf73 other 0.00587761734613183 1 1 2.31064177266032 -0.175723499603659 9.61034231149291e-08 84.9951759712055 33.5335209643974 2.53463321258287 0.0116093611391381 -10.177121008238 42.3061213874942 -0.240559065082397 0.810011262069293 ZNF880 other 0.000620924216745557 1 1 2.53463321258287 -0.240559065082397 0.233998934844967 49.298739899095 31.2425355501471 1.5779365864837 0.115302093609914 -17.2967439741085 23.1884168976442 -0.745921726802562 0.456114830593469 TRIM16 other 1 1 1 1.5779365864837 -0.745921726802562 4.26748534372029e-15 -85.5740577925348 95.1139878725816 -0.899700030527299 0.3687765426358 472.390207517343 125.593557336823 3.76126146543062 0.000192132661893744 FXYD7 other 3.43873968996981e-11 1 1 -0.899700030527299 3.76126146543062 0.692712947953655 10.5928942398492 13.2257135927629 0.800931773212267 0.423605387908873 2.68489477944175 25.6071995950721 0.104849215138638 0.916543453420717 SLC12A8 other 1 1 1 0.800931773212267 0.104849215138638 0.792952962467202 -96.6909919883081 149.055536363202 -0.648691047293287 0.516881180433842 -130.349973673578 231.946129446751 -0.561983827815947 0.574417150789035 APOL6 other 1 1 1 -0.648691047293287 -0.561983827815947 0.338342959901258 53.3618009565836 97.9593582216593 0.54473408079949 0.58621428958876 -263.75850809419 235.462886516794 -1.1201701975032 0.263256490103751 FADS3 other 1 1 1 0.54473408079949 -1.1201701975032 1.85508137794878e-37 1373.12637773387 260.629933521064 5.2684906878622 2.16648713426816e-07 -1142.47536283445 345.995528010089 -3.30199459341317 0.00103899520867454 CCNL2 other 1.72114450246088e-33 1 0.00197085334604375 5.2684906878622 -3.30199459341317 9.36898666014808e-08 26.7904761904763 31.1995585064066 0.858681259383048 0.390986059657016 -361.007814407813 72.7210071266176 -4.96428513124478 9.89447414285112e-07 PPT2 other 0.000605892367311776 0.00872296840433755 1 0.858681259383048 -4.96428513124478 2.00390104344614e-07 34.0038185639211 10.1622133780839 3.346103579881 0.000890841072339839 -24.1050218187494 15.6262918720541 -1.54259385503087 0.12365815159952 EXOC3-AS1 other 0.00126947131102313 1 1 3.346103579881 -1.54259385503087 0.0178028283320307 14.4177190239027 79.6935525310445 0.180914497672648 0.85651875480756 -474.934664056029 174.234767217398 -2.72583177078223 0.00667232286415433 TIAF1 other 1 1 1 0.180914497672648 -2.72583177078223 3.32856058194892e-13 11.1641527416632 12.1730274787106 0.917122117828793 0.359583354451061 -53.5797480549886 15.7065758483415 -3.41129400655753 0.000706545062600105 BTBD19 other 2.59061870093084e-09 1 1 0.917122117828793 -3.41129400655753 0.297689179883112 2.07609462621167 16.7368320082054 0.124043464449775 0.901338026316642 -46.9165335908196 34.4987567160875 -1.35994853312906 0.174548996234972 URAHP other 1 1 1 0.124043464449775 -1.35994853312906 6.66500090194491e-20 7.53860191027373 2.16390551124547 3.48379440372828 0.000544224744025173 -5.60240427974452 2.7798185846514 -2.01538485665138 0.0444760713948547 DCDC2B other 5.68457926926881e-16 1 1 3.48379440372828 -2.01538485665138 2.45372880221593e-05 -2.04365210222585 18.9437485618115 -0.10788002678338 0.9141402601376 61.3660346248971 22.9654322636438 2.67210448818961 0.00781886620272485 C10orf55 other 0.131078192614375 1 1 -0.10788002678338 2.67210448818961 0.00166864594946833 5.01385889885753 4.7830213378769 1.04826187145615 0.295098703683303 -6.98844665146695 5.66328162665939 -1.23399242915441 0.217870466232467 MEG9 other 1 1 1 1.04826187145615 -1.23399242915441 7.08657308744072e-16 31.5477564673788 17.1845030436239 1.835825940808 0.0670626691715783 -70.028132925709 20.6608990339471 -3.38940395626775 0.00076399983324525 NUTM2A-AS1 other 5.77555706626419e-12 1 1 1.835825940808 -3.38940395626775 6.45049755082925e-05 216.964070691831 62.731058921194 3.45863874168603 0.000596037230308893 -221.653417134678 149.715568643234 -1.48049677894801 0.139459659550889 EXOSC6 essential 0.327362750704585 1 1 3.45863874168603 -1.48049677894801 7.73473416007964e-14 65.7107764082489 79.04145155503 0.831345770041937 0.406232334354517 -1303.03974196521 184.236481647207 -7.07264777483316 6.06951008470514e-12 VPS52 other 6.10038483205481e-10 5.80002383694423e-08 1 0.831345770041937 -7.07264777483316 0.000191442094071785 122.148459383755 35.4602148358628 3.44466213611936 0.000626854506859227 289.749263808087 82.6518918612469 3.50565797446606 0.000502440497555591 HLA-DQB1-AS1 other 0.914327441286845 1 1 3.44466213611936 3.50565797446606 0.0756261354168676 -142.92323852983 97.5329889347233 -1.46538355986902 0.143538704301968 -336.126685793029 147.478386293424 -2.27915896180386 0.0231412788029188 CKMT1A other 1 1 1 -1.46538355986902 -2.27915896180386 0.340192547235479 10.0856668614928 54.8321923247579 0.183936961735139 0.854148032050079 71.931273108168 65.0644446615677 1.10553887737486 0.269533038828248 HBD other 1 1 1 0.183936961735139 1.10553887737486 0.0140153420635359 3.61413374202719 3.83929342374885 0.94135387508314 0.347043615695281 -4.56670197660516 4.88979393303214 -0.933925240848209 0.350858197499049 RAET1E-AS1 other 1 1 1 0.94135387508314 -0.933925240848209 0.18308137065095 -2.66207389375031 4.11864818611771 -0.646346513092105 0.518396607560901 -7.70123582691838 4.77419011470911 -1.61309785364247 0.107450102981489 TSSC2 other 1 1 1 -0.646346513092105 -1.61309785364247 3.42723596030931e-12 42.7365652361133 9.11519923268287 4.68849491329601 3.68410986912162e-06 -33.4597459451702 15.2641503399627 -2.19204771965395 0.0289028887948464 ENTPD3-AS1 other 2.61121107815967e-08 1 0.0325159537048674 4.68849491329601 -2.19204771965395 5.75695744179768e-07 -0.168188790903547 4.45205543250565 -0.0377777845431922 0.969882147869801 -16.879119441072 5.39235771537094 -3.13019282696286 0.00186431785841066 CFL1P1 other 0.00355146704584499 1 1 -0.0377777845431922 -3.13019282696286 0.00127626123521721 1908.27619047621 666.266875504892 2.86413186762456 0.00438249782981513 5016.75738705738 1552.95781483162 3.23045309997769 0.00132907615157558 HLA-DPB1 other 1 1 1 2.86413186762456 3.23045309997769 0.00028836900904131 101.917740557804 30.4102791232963 3.35142404134422 0.000873994441259165 -44.29569453213 62.6831183242191 -0.706660672224652 0.480154848085514 AFG3L1P other 1 1 1 3.35142404134422 -0.706660672224652 5.65568841222227e-11 18.5874328234806 2.64264050952081 7.03365923458542 7.78377430914268e-12 11.6672178586192 5.80219140315396 2.01082953800475 0.0449557864103783 MIR181A2HG other 4.18803726925059e-07 1 7.46152605274417e-08 7.03365923458542 2.01082953800475 5.61602078791869e-38 172.698910707418 30.4812402463273 5.66574421879786 2.66667036002273e-08 -120.346499059419 40.4862186959507 -2.97252998515901 0.00311755597361849 CPTP other 5.21728331197647e-34 1 0.000246293674451699 5.66574421879786 -2.97252998515901 4.40015804008465e-13 17.8004433900693 16.8059048778312 1.05917792106214 0.290102507050887 -70.6848356452464 21.6842704187855 -3.25972856269173 0.00120215291156693 SLC44A3-AS1 other 3.4154026707137e-09 1 1 1.05917792106214 -3.25972856269173 0.178619378276525 20.0771657364715 12.6695482215826 1.58467889977876 0.113762661139249 7.46943163741252 19.4065869543343 0.384891565682768 0.700505005766112 MSL3P1 other 1 1 1 1.58467889977876 0.384891565682768 0.000107681229710464 16.1291109942138 7.20806753477234 2.23764704151363 0.0257461589544537 -40.2697828210713 15.8348444098032 -2.5431119990128 0.0113299371888611 MDC1-AS1 other 0.531406868621142 1 1 2.23764704151363 -2.5431119990128 0.0912348274925014 2047.6647199021 1288.74391129248 1.58888410797495 0.112813076123074 -2560.36464618271 2978.4635821311 -0.859625970095212 0.39046873701591 C4B other 1 1 1 1.58888410797495 -0.859625970095212 1.07793423934191e-06 2.69508304467551 4.29719111677622 0.627173186259722 0.530873251655583 -9.88134114930261 5.24889592916286 -1.88255611897388 0.0604246534997737 ADM5 other 0.00651611247682187 1 1 0.627173186259722 -1.88255611897388 0.000309434120894714 3.00373399715486 10.7387739338768 0.27970921221083 0.779833560563955 -50.2989420341394 16.7180710807979 -3.00865702694086 0.002776448300923 PRKAR2A-AS1 other 1 1 1 0.27970921221083 -3.00865702694086 0.00464397042560832 44.3020413414548 68.1099255983135 0.65044912253658 0.515743971334189 -460.658055813293 162.55489406124 -2.8338614993637 0.00481196517467386 ATXN1L other 1 1 1 0.65044912253658 -2.8338614993637 1.27872357245062e-09 32.0610841423954 84.5645453500309 0.379131514391612 0.704775197877791 -783.816343042071 146.394802455736 -5.35412685350674 1.39487848075788e-07 SMIM13 other 9.06998629939228e-06 0.00126152809799743 1 0.379131514391612 -5.35412685350674 0.000607905322466834 67.1172963944251 24.0328085815207 2.7927362782739 0.00545589923864408 199.451445685981 56.0176971709272 3.56050776377674 0.000410769065703088 HLA-DPB2 other 1 1 1 2.7927362782739 3.56050776377674 0.145643241520354 0.964525271610932 2.56772787028283 0.375633758847152 0.707371456776297 -2.6147924539441 3.11324507538843 -0.839892906156083 0.401427692840151 ZMIZ1-AS1 other 1 1 1 0.375633758847152 -0.839892906156083 1.18666136297603e-20 138.070286506991 23.6425211872255 5.83991383209982 1.0189679430235e-08 -152.815908639749 45.9928274628068 -3.3226030463843 0.000966615642502064 SVIL-AS1 other 1.02041010602309e-16 1 9.48353464571972e-05 5.83991383209982 -3.3226030463843 0.302066486126917 44.3395364357391 81.0994351486922 0.546730521050418 0.584842296253331 -191.535860776714 174.082747453318 -1.10025757048714 0.271824239014867 SH3BP5-AS1 other 1 1 1 0.546730521050418 -1.10025757048714 2.20571241170936e-22 -0.595993254855028 2.7774019572084 -0.214586604329346 0.830189736693469 -24.2548658904909 3.59392725109135 -6.74884720694485 4.75079574880758e-11 TMEM72-AS1 other 1.92448407921642e-18 4.50850516561839e-07 1 -0.214586604329346 -6.74884720694485 0.116443430421314 7.8164633409832 3.85458857678345 2.02783336931534 0.043186272537382 3.29862704835531 8.1996240289377 0.402290036313124 0.687668187963091 LINC00240 other 1 1 1 2.02783336931534 0.402290036313124 0.000364840314795181 129.205245982252 34.9217302544486 3.69985235670827 0.00024331420447093 -84.7955139810913 94.3939418447283 -0.898315213073464 0.369513330184484 NDUFAF8 other 1 1 1 3.69985235670827 -0.898315213073464 0.479294793252489 63.2395239691582 57.9531210447573 1.09121860616132 0.275888703711405 -6.84831589533711 102.837466461704 -0.0665935882219284 0.946941316173261 LINC00320 other 1 1 1 1.09121860616132 -0.0665935882219284 0.480274597641277 -15.7381556912123 17.3626891750663 -0.906435376025343 0.365204971636748 -36.5668101249122 32.5828072052661 -1.12227316371323 0.262362550896765 TMEM233 other 1 1 1 -0.906435376025343 -1.12227316371323 0.386873667031209 2.16650373854 17.3200115733759 0.125086737347815 0.900512404227917 49.9295410710982 37.7697432430988 1.32194547232516 0.186877860752312 LINC00092 other 1 1 1 0.125086737347815 1.32194547232516 0.000993659711992302 9.43098908518059 4.01809144439947 2.34713152144055 0.0193630210044952 -21.6169911106109 9.50538764795117 -2.27418301191223 0.0234379403370369 TAF1A-AS1 other 1 1 1 2.34713152144055 -2.27418301191223 0.76566887861539 1.20853586932456 2.20542869928488 0.547982290117307 0.583983217403806 -0.971397907422231 4.55046494544479 -0.213472231753953 0.831057974930507 PPP1R26-AS1 other 1 1 1 0.547982290117307 -0.213472231753953 0.2182867710721 -1.14128231515266 2.80982042045992 -0.406176247721146 0.684811473010142 -10.6651178262181 6.16703697478282 -1.72937471752287 0.0844466042498642 TMEM246-AS1 other 1 1 1 -0.406176247721146 -1.72937471752287 0.649077122692795 1.24981207246487 1.90896321576307 0.654707257921302 0.513000689330327 3.57900405240106 3.91311209900724 0.914618329822204 0.360896407306763 SFTA1P other 1 1 1 0.654707257921302 0.914618329822204 5.56611872181537e-19 24.5452527161083 14.329755680947 1.71288703468573 0.0874426234044159 -73.4135495394423 17.3741313561837 -4.2254515080153 2.90437948105867e-05 NUTM2B-AS1 other 4.71116288614453e-15 0.240250270673173 1 1.71288703468573 -4.2254515080153 4.1353748346755e-05 -16.7217830910915 38.3084502741309 -0.436503773225811 0.662686350342009 -138.437992727574 49.4285074863552 -2.8007722621564 0.0053237283600305 GBP1P1 other 0.21524626014486 1 1 -0.436503773225811 -2.8007722621564 0.000255143775099451 2.95775045560715 1.52760933312155 1.9361955910306 0.0534867600158924 -8.24844066839498 3.27906636165294 -2.51548451865946 0.0122437098592427 MKRN2OS other 1 1 1 1.9361955910306 -2.51548451865946 5.21570239365665e-25 0.51089179511747 1.55051039330296 0.329499110308541 0.741935977817725 -11.2479029001769 1.98116108836238 -5.67742974877141 2.49268421832566e-08 MTOR-AS1 other 4.61693975886486e-21 0.000228878264926662 1 0.329499110308541 -5.67742974877141 0.307359513677655 7.62341238426411 110.16019022529 0.0692029704076706 0.94485964083086 -321.859825147146 234.070755482866 -1.37505355798583 0.169817779649398 ZNF469 other 1 1 1 0.0692029704076706 -1.37505355798583 4.20482174563546e-09 1253.51698345151 198.576062128929 6.31252815678075 6.76405774330167e-10 301.489527387912 526.275626520856 0.572873817814864 0.567025445308347 MCRIP1 other 2.91730532712188e-05 1 6.38729972699977e-06 6.31252815678075 0.572873817814864 0.262919480546991 1.33091137423836 24.7765917710607 0.0537164831440973 0.957185597547788 75.9653749551501 50.1196900480019 1.51567926462424 0.130323449235017 FAM225B other 1 1 1 0.0537164831440973 1.51567926462424 6.09092786434317e-06 361.511897122613 284.617421096004 1.27016784752846 0.204699169993104 -2362.22815780692 610.9411557137 -3.86653957703566 0.000127126225186175 FGD5-AS1 other 0.0346001062969004 1 1 1.27016784752846 -3.86653957703566 7.04204287376748e-05 44.5268550498274 18.345484129354 2.42712891825958 0.0156239661876937 -6.1150042897678 21.7242255244005 -0.281483189488135 0.778473670519694 MEG8 other 0.355764005982733 1 1 2.42712891825958 -0.281483189488135 0.386939101814265 7.54428680058906 5.93587265750245 1.27096506880984 0.204415660674197 12.4254603382391 12.2474965784872 1.01453062334913 0.310889714089276 DBH-AS1 other 1 1 1 1.27096506880984 1.01453062334913 0.00608012142089507 612.637052026215 368.38254252257 1.66304583227823 0.0970218827391323 -789.321817072727 600.591443011597 -1.31424086416344 0.189456143697191 MIAT other 1 1 1 1.66304583227823 -1.31424086416344 2.64003082844185e-05 2.59134810063175 19.6995063753582 0.131543808827272 0.895405811141365 -184.391925428484 44.5418523757452 -4.13974533149172 4.17515073162534e-05 TRAM2-AS1 other 0.140660842539382 0.341569081354269 1 0.131543808827272 -4.13974533149172 6.48467399557278e-34 38.6670578912344 17.9672106287528 2.15209019865086 0.0319385935535772 -123.218204473373 23.0908647334647 -5.33623170442804 1.52875568362585e-07 FAM229A other 5.95228226053625e-30 0.00138016063117742 1 2.15209019865086 -5.33623170442804 2.12176922685065e-10 -3.35977710313764 34.720299034005 -0.0967669402802978 0.922955840885524 -198.729320552354 45.3452677639131 -4.3825812560425 1.47045393619407e-05 ERCC6 other 1.54507235099264e-06 0.123312267089235 1 -0.0967669402802978 -4.3825812560425 1.95485983077839e-07 12.9254720232852 7.54209221312155 1.71377804169483 0.0872818953299593 -14.5372879246294 9.96261668869401 -1.4591837043301 0.145236265117248 LINC01529 other 0.00123899016074734 1 1 1.71377804169483 -1.4591837043301 0.00136940456356582 4.81326738434685 1.9244495592062 2.50111381788164 0.0127444539754001 -1.80109642742292 3.02854597799209 -0.594706648177433 0.552346659734213 LINC00694 other 1 1 1 2.50111381788164 -0.594706648177433 1.72136702477913e-16 13.3749176046391 3.37974862013506 3.95737053488453 8.87972182840009e-05 -5.4671179128923 4.44430361021532 -1.23014051072614 0.219324962371148 LINC00115 other 1.41565224117835e-12 1 0.740036017178863 3.95737053488453 -1.23014051072614 1.88641469996815e-23 146.432800933889 40.0610152594797 3.65524438123764 0.00028826601396678 -490.195555904646 70.938102686192 -6.91018701293884 1.72460711493649e-11 NOL7 essential 1.65570618216204e-19 1.6428607376885e-07 1 3.65524438123764 -6.91018701293884 0.944385671114371 8.31992093459407 24.7366114558646 0.336340365350306 0.736775657478984 3.67778439471913 92.101063908709 0.0399320511472545 0.96816553484236 ELFN1 other 1 1 1 0.336340365350306 0.0399320511472545 6.99952012328936e-10 15.4099624757739 11.4804939994733 1.34227346632304 0.180205844912107 -72.7577316399328 17.5096980581647 -4.15528191281436 3.91141099241115e-05 PIGBOS1 other 5.0144562163245e-06 0.320579244938018 1 1.34227346632304 -4.15528191281436 1.49214021043308e-16 3.10186570845941 1.55951152476932 1.98899825951478 0.0473259250765448 -5.95754999342191 2.0489361318022 -2.90763089241916 0.00382766582690622 LINC01534 other 1.22788217916538e-12 1 1 1.98899825951478 -2.90763089241916 1.87146157310863e-08 -59.2533825338254 65.0734044993226 -0.910562202634445 0.363026917332658 -322.747027470275 78.3733992435885 -4.11806851030106 4.56789177370631e-05 KCNIP2-AS1 other 0.000126099080796059 0.372922684405383 1 -0.910562202634445 -4.11806851030106 7.48633275421646e-26 5.83431583419641 6.16285692909258 0.946690131107012 0.344318678800911 -41.7119679226746 7.87472414224936 -5.29694338102361 1.86838883356228e-07 LINC01772 other 6.65460118522302e-22 0.0016830446612729 1 0.946690131107012 -5.29694338102361 2.84040952829948e-06 -4.36650000000011 3.88618378491325 -1.12359585693078 0.261801372925008 27.399 7.83772017680789 3.49578696124859 0.000520982178358286 SLC39A12-AS1 other 0.0166107149214953 1 1 -1.12359585693078 3.49578696124859 1.57354081012265e-07 379.205836234028 80.1777107731954 4.7295667658399 3.03934900718069e-06 -502.060747767484 216.731738522997 -2.31650773065806 0.0209911996840728 BAIAP2-AS1 other 0.00100281755829116 1 0.0268982387135491 4.7295667658399 -2.31650773065806 2.57001338097939e-31 16.8070812778767 5.71263972556942 2.9420866858887 0.00343310317374942 -31.0556334834101 7.33558600441141 -4.23355863658802 2.80433476037805e-05 AP4B1-AS1 other 2.33717016866266e-27 0.232198918159302 1 2.9420866858887 -4.23355863658802 8.2034900101303e-20 34.172313792799 18.5549367879946 1.84168311556357 0.0661989859777983 -102.187257716093 21.5446122291152 -4.74305393057845 2.85493885239672e-06 TEX22 other 6.98855313963e-16 0.0247523198502795 1 1.84168311556357 -4.74305393057845 0.000776218743540923 7.04310344827583 1.86320425749746 3.78010270207073 0.000178535604621214 8.09675456389454 4.00368379733978 2.02232618102218 0.0437513373708774 GAS1RR other 1 1 1 3.78010270207073 2.02232618102218 1.74436547503689e-11 85.3997107955341 19.3381708643443 4.416121431267 1.26887160577381e-05 -1.80064024267669 24.8534207932058 -0.0724503985853303 0.942276701179302 ZNF32-AS1 other 1.30809966973017e-07 1 0.109795460047608 4.416121431267 -0.0724503985853303 0.532244240901365 -4.02282323502884 3.57972960261699 -1.1237785200558 0.261725354194384 -3.78653129615775 6.05415901035201 -0.625442987156955 0.53200758090801 TMEM191A other 1 1 1 -1.1237785200558 -0.625442987156955 0.0383115309833504 5.60087776957549 7.83725240735504 0.714648129020219 0.475207203132153 -30.4014430612719 15.9472190826304 -1.90637896825441 0.0572552265601202 ZNF192P1 other 1 1 1 0.714648129020219 -1.90637896825441 3.30149993217393e-06 7.73693227968065 4.69731954170028 1.64709515948326 0.100257336398222 -8.64033606335443 5.42250777198182 -1.59342068774879 0.111788843883475 MRPL23-AS1 other 0.0192048251054558 1 1 1.64709515948326 -1.59342068774879 5.16529594055856e-32 17.2237466311525 6.19192632477796 2.78164592531229 0.00564189003755563 -35.6401703205199 7.95103669588761 -4.48245577069887 9.43339511109917e-06 SLC16A1-AS1 other 4.7097168386013e-28 0.0799951905421209 1 2.78164592531229 -4.48245577069887 0.174990955560833 -6.14100305379385 7.46515414199406 -0.82262240497468 0.411170368992639 15.8476458941574 14.5393184331026 1.08998547401479 0.276318838681607 LINC00323 other 1 1 1 -0.82262240497468 1.08998547401479 0.42947483885057 2.00137551581828 5.61242420512235 0.356597335246268 0.721565385118557 -12.4789776935583 12.3988640458223 -1.00646136996422 0.314750639683829 LINC00606 other 1 1 1 0.356597335246268 -1.00646136996422 2.84355433005805e-07 19.536494153879 5.58586944701351 3.49748491961699 0.000517881185428443 57.1586566996915 10.368669986188 5.51263149235458 6.06244455405045e-08 KIF4B other 0.00178660518557547 0.000552531196656158 1 3.49748491961699 5.51263149235458 8.62205592912018e-11 -2.60793725814549 10.4544320683669 -0.249457573696099 0.803124335211634 -53.6261155256222 13.7409971229504 -3.90263639863916 0.000110194747637883 LINC01535 other 6.35790404213322e-07 0.87241181704912 1 -0.249457573696099 -3.90263639863916 4.51780167605956e-06 16.6678656775189 9.99076554006406 1.66832717780023 0.095965454642652 -19.6734825154495 12.6235918366518 -1.5584694728745 0.119844226569874 ENTPD1-AS1 other 0.0260089842490749 1 1 1.66832717780023 -1.5584694728745 4.77402994843813e-17 15.173203920817 5.31049386779744 2.85721145689039 0.00447738229556014 -9.53287809971054 6.58941842438526 -1.44669491080313 0.14869763891139 LENG8-AS1 other 3.95480640928615e-13 1 1 2.85721145689039 -1.44669491080313 0.000106660548154732 10.4276147104973 12.8257508746945 0.81302177255534 0.41666951266583 -49.2724988200477 19.2801756703922 -2.55560424668295 0.0109541540418948 HSBP1L1 other 0.526903107884377 1 1 0.81302177255534 -2.55560424668295 4.78910130723723e-39 318.331785264935 72.2270737239919 4.40737480908344 1.31958531291528e-05 -240.702773152745 88.998994366508 -2.70455610050495 0.00710795254868836 SRRM5 other 4.46009004743003e-35 1 0.114130933714043 4.40737480908344 -2.70455610050495 1.2992111467e-15 82.9515904017867 10.7401324877551 7.7235164925908 7.80457693456024e-14 -31.8532087053568 29.6971584965734 -1.07260122913888 0.284042029482246 CACTIN-AS1 other 1.05508937223507e-11 1 7.5462454380263e-10 7.7235164925908 -1.07260122913888 1.8102120417324e-06 6.20687856034935 7.10101139997017 0.874083734096725 0.382552748226082 -15.8233734448302 8.24999970248168 -1.91798472914738 0.0557643429326276 ATE1-AS1 other 0.0107580901640157 1 1 0.874083734096725 -1.91798472914738 0.0178230746039451 -7.48132269292803 5.63027606693366 -1.32876658337687 0.184653371147882 14.0532303251549 9.70568336348634 1.44793826450432 0.14838753912358 ERVMER34-1 other 1 1 1 -1.32876658337687 1.44793826450432 0.000565237356815571 3.92437915526865 3.02279946309728 1.29825984263196 0.194881234624045 -3.39739765471334 3.88179616375183 -0.87521279103684 0.381937813995376 LINC01359 other 1 1 1 1.29825984263196 -0.87521279103684 0.0215852343438104 -4.20333413360544 3.23875624609262 -1.29782355145637 0.195032579792111 -13.9080037212653 5.05011513242767 -2.75399735581463 0.00613284466075577 BSN-AS2 other 1 1 1 -1.29782355145637 -2.75399735581463 0.0132827648890503 229.16748026148 121.687297910905 1.88324898486339 0.0603640307835449 -198.685181254775 209.769178072416 -0.94716098466184 0.344106606115507 DANCR other 1 1 1 1.88324898486339 -0.94716098466184 0.0280422594148943 7.38740085067248 9.60606085923684 0.769035399517485 0.442286781478408 49.668672918069 18.8765625395335 2.63123504684961 0.00880764133017302 ITGB2-AS1 other 1 1 1 0.769035399517485 2.63123504684961 3.59476961530988e-11 59.2922899451597 832.038528645543 0.0712614715591119 0.943222333826841 -4181.71515516642 990.360309506453 -4.22241795741025 2.9434903789515e-05 C14orf132 other 2.67666545555974e-07 0.243426654339289 1 0.0712614715591119 -4.22241795741025 0.641781029459527 8.17079450643978 19.1957040049159 0.425657454623561 0.670566539978672 -10.2420880788425 29.6449464812619 -0.345491872799176 0.729890485795574 LINC01630 other 1 1 1 0.425657454623561 -0.345491872799176 0.000155783635499045 20.411024878509 12.4824007518462 1.63518423132586 0.102728845936237 -49.9808732864289 20.0649928842752 -2.49094896642593 0.0131095460436735 ZNF717 other 0.754148579450878 1 1 1.63518423132586 -2.49094896642593 6.39554837469634e-05 -8.8494419648202 39.0906369316579 -0.226382649642974 0.821009670918518 -113.176575565985 45.4157478267605 -2.49201171359546 0.0130717939530632 WDR11-AS1 other 0.32476594646708 1 1 -0.226382649642974 -2.49201171359546 0.00231828342627128 10.4083632970974 4.26256677911085 2.44180650684575 0.015009560335374 1.48362432253952 5.11647045251685 0.289970270777134 0.771976519636433 SMIM2-AS1 other 1 1 1 2.44180650684575 0.289970270777134 9.87090269921724e-07 -5.54216315640236 3.45299711450563 -1.60502976765326 0.109211293499815 -17.6431453518383 4.18229195791451 -4.2185350830065 2.99259898748052e-05 KLLN other 0.00598571539680534 0.24736823230514 1 -1.60502976765326 -4.2185350830065 2.92828228670581e-23 32.6864038757293 30.026239563442 1.08859465424123 0.276932652923756 -232.429230511794 39.2147507604753 -5.92708677230866 6.26273296576745e-09 PARG other 2.56751790898366e-19 5.80054327289382e-05 1 1.08859465424123 -5.92708677230866 1.96276312104076e-08 37.7798603596639 13.1594085068336 2.8709390957842 0.00429516540944036 -19.7086618230537 15.3471246580876 -1.28419246354839 0.199767700833959 RBM26-AS1 other 0.000132152840939674 1 1 2.8709390957842 -1.28419246354839 2.58686904131305e-06 59.2429004831814 75.2244368363636 0.787548607536312 0.431386749559215 -193.906912172255 96.1178511268821 -2.01738709198029 0.0442645887809073 TP73-AS1 other 0.0152056162248381 1 1 0.787548607536312 -2.01738709198029 0.0452632854202424 10.5449361704828 4.26443810123571 2.4727609875325 0.0137877658165033 12.7891626303727 5.63099038486716 2.27121017019361 0.023621004613043 HPN-AS1 other 1 1 1 2.4727609875325 2.27121017019361 0.0103006060566239 10.9077251472602 4.87764870391143 2.23626706419287 0.0258549578809018 -12.5613485987571 11.383667552095 -1.10345356988621 0.270457589957174 FGF7P6 other 1 1 1 2.23626706419287 -1.10345356988621 0.496881196945726 7.82554371533572 7.00032162822985 1.1178834532085 0.264230941978231 1.6543991311234 13.8331775614586 0.119596464642572 0.904857781233173 LINC00310 other 1 1 1 1.1178834532085 0.119596464642572 0.0400981980676913 44.6306982509307 54.9695462270175 0.811916803289796 0.41728039549654 -70.4406762153965 73.6143542043861 -0.9568877833231 0.339151749364706 LINC01268 other 1 1 1 0.811916803289796 -0.9568877833231 0.0594495283848268 12.2572119936876 5.4787548794178 2.23722584117326 0.0257738802119173 19.5368602990906 12.0358515866446 1.62322210094127 0.105261395021901 LTB other 1 1 1 2.23722584117326 1.62322210094127 1.34362055628124e-05 -2.701515505107 2.53451721724987 -1.06588958509358 0.287060750453558 -11.0888712057539 3.25475749582231 -3.40697309092527 0.000717529052632779 SLC2A1-AS1 other 0.0737378961287145 1 1 -1.06588958509358 -3.40697309092527 3.44319185579494e-09 41.2825403368276 18.1760158550719 2.27126454257069 0.0236154570803168 -37.4508744553055 22.0347129070348 -1.69963069695131 0.0899103959899716 DNAJC9-AS1 other 2.39680585081886e-05 1 1 2.27126454257069 -1.69963069695131 0.000243376548620423 117.20206640409 46.6851550968196 2.51047824862157 0.0124177888608213 -42.8534698048871 61.8069515593491 -0.693343850873113 0.48846297243798 SOX21-AS1 other 1 1 1 2.51047824862157 -0.693343850873113 0.00050328909478551 5.02375923970435 9.35511238961466 0.537006829044764 0.59153557437754 30.4936055379562 12.0128758002699 2.53841012301743 0.0114810256669722 FAM212B-AS1 other 1 1 1 0.537006829044764 2.53841012301743 0.850127598003663 -2.7421703118937 5.81240459433073 -0.471778980177729 0.637320023403552 0.113271644881302 10.1046489561841 0.0112098545305702 0.991061133115087 SLC9A7P1 other 1 1 1 -0.471778980177729 0.0112098545305702 0.00277682799546156 12.2246006208902 22.3153505161796 0.54781127511427 0.58410311977623 -101.647560319691 39.6515816324832 -2.56351843066001 0.0106976197535715 MELTF-AS1 other 1 1 1 0.54781127511427 -2.56351843066001 8.04124244663067e-13 -4.00556352345979 3.1944460698673 -1.25391489975168 0.21054175937524 -21.0424864414289 4.10197999658202 -5.12983643483454 4.36462645113894e-07 EFCAB14-AS1 other 6.20623092030955e-09 0.00389717495822196 1 -1.25391489975168 -5.12983643483454 3.14014069672251e-07 135.254234523601 53.8258670045203 2.51281107115734 0.0123355195405689 -215.332124664373 85.565314675765 -2.51658192902506 0.0122061995567227 GUSBP11 other 0.00196541406207862 1 1 2.51281107115734 -2.51658192902506 4.63779812899722e-14 3.88979933110376 3.26862881206704 1.19004009165663 0.234676737930653 -19.6086044390393 4.3980230116662 -4.4585042840898 1.05053245206835e-05 TSTD3 other 3.6726723383529e-10 0.0889065614185447 1 1.19004009165663 -4.4585042840898 0.00136049686598552 14.1066339066341 4.77504546114178 2.95424075465472 0.00330369418743805 -8.10740171990159 10.0621528565344 -0.805732315489183 0.420835420338317 CCDC183-AS1 other 1 1 1 2.95424075465472 -0.805732315489183 2.86869951820107e-14 -25.8326172757517 38.1102167036537 -0.677839684739317 0.498231254020564 -263.041149267959 50.5434855894692 -5.2042542416735 2.99950075100352e-07 FNDC10 other 2.28147672682531e-10 0.00269115207380035 1 -0.677839684739317 -5.2042542416735 1.56360792722756e-05 85.6759956942957 19.5799462341865 4.37570127463913 1.51559191220097e-05 2.54386437029115 39.607579827028 0.0642267056306034 0.948819081746443 ZNF883 other 0.0853104485095358 1 0.13068949058909 4.37570127463913 0.0642267056306034 1.59776372193842e-08 -0.689849882935985 5.87156744711507 -0.117489901827652 0.906525702217182 -32.0458011981819 7.86311103973477 -4.07546084955997 5.45321894151937e-05 HDAC2-AS2 other 0.000108104693426353 0.442471694027017 1 -0.117489901827652 -4.07546084955997 0.0143529321660644 14.7543154483709 11.8578118854545 1.2442696503281 0.214067285892773 -43.9640609281658 23.4319544176921 -1.87624387383457 0.0612880631419539 TTC3-AS1 other 1 1 1 1.2442696503281 -1.87624387383457 0.00620062520605689 1.09277035777484 4.19856998847367 0.260272035663291 0.794776250914094 -8.04168649754055 5.0699258369438 -1.58615466106861 0.113425877917818 TNKS2-AS1 other 1 1 1 0.260272035663291 -1.58615466106861 0.00131400215821146 75.2761334656395 20.9577599162194 3.5918024524836 0.000365611084055966 29.3967962040579 47.3289519977121 0.621116567412668 0.534846023916724 SAPCD1 other 1 1 1 3.5918024524836 0.621116567412668 0.641465817605705 -11.6634192530249 13.9677001653682 -0.835027893993848 0.404157233764161 -22.2903734876382 30.6845569654299 -0.726436217174363 0.467959420759636 HCG22 other 1 1 1 -0.835027893993848 -0.726436217174363 2.13476459402005e-29 30.7629601162183 30.6252288224423 1.00449731476537 0.315710524944804 -248.479775610974 40.2715794329731 -6.17010256636536 1.59230794144587e-09 LINC01128 other 1.92769242840011e-25 1.4870563865163e-05 1 1.00449731476537 -6.17010256636536 0.185639474668285 -0.407626911249786 3.13087647609249 -0.130195782031787 0.896473422347276 -4.85937882382974 3.68035815458752 -1.32035487300946 0.187430536049559 MIR4500HG other 1 1 1 -0.130195782031787 -1.32035487300946 1.15031003229702e-09 11.0772586553232 3.89671676914276 2.84271588405952 0.00468317798446821 -11.4155264090748 5.0072101301484 -2.27981772531214 0.0231007015522217 UBAC2-AS1 other 8.1764037095672e-06 1 1 2.84271588405952 -2.27981772531214 6.64217495653615e-29 29.2847866648791 9.03568929859328 3.24101302038332 0.00128235386217755 -51.6937294356765 10.7236613787221 -4.82052981813163 1.98078924377292e-06 MED4-AS1 other 5.98592807083038e-25 0.0172922900981376 1 3.24101302038332 -4.82052981813163 0.0165340018675902 564.261987928603 268.627223944254 2.10053910264024 0.0362551980676557 -134.920482856042 427.790876356208 -0.315388874127596 0.752617313138072 RPL41 essential 1 1 1 2.10053910264024 -0.315388874127596 9.45191549085986e-15 2717.66935301352 780.625265103072 3.48140071107574 0.000548860436567555 12943.8699827798 1574.14050297483 8.2228174412121 2.28024689808467e-15 VIM-AS1 other 7.56625835043332e-11 2.21685603431791e-11 1 3.48140071107574 8.2228174412121 0.755657142138342 -6.10071250975831 9.83014158395884 -0.620612883105738 0.535177148926029 -14.1983971914754 23.8119823862337 -0.596271110954788 0.551302153897223 PGA4 other 1 1 1 -0.620612883105738 -0.596271110954788 3.5246030640076e-06 0.572190622144986 2.71918009731573 0.210427629530619 0.833432459563047 -10.5124738439774 3.51177587355249 -2.99349224509111 0.00291523704642003 LINC00242 other 0.0204673699926921 1 1 0.210427629530619 -2.99349224509111 0.0044778432342401 841.073109243704 272.753004981152 3.08364378717596 0.00217412126246924 1457.16617108381 635.742112022764 2.29207117717512 0.0223750737873847 HLA-DRB6 other 1 1 1 3.08364378717596 2.29207117717512 0.232325973484647 -102.084569850386 60.9528722558849 -1.67481147437692 0.0946850064900279 -123.962935273057 126.9980272476 -0.976101266765145 0.329553070053 RALGAPA1P1 other 1 1 1 -1.67481147437692 -0.976101266765145 0.585035410049648 4.2263950147218 5.3410681955812 0.791301451312381 0.429198352683028 8.43837576416895 8.31440360372097 1.01491052952884 0.310711343135597 SPINK8 other 1 1 1 0.791301451312381 1.01491052952884 0.330592564549615 -0.903449522217468 6.03764326740789 -0.149636121612952 0.881121059455092 9.53135518557844 9.12944323575083 1.04402370872451 0.297054250481309 PATL2 other 1 1 1 -0.149636121612952 1.04402370872451 2.17197456907213e-05 -7.44428667557585 6.74754639445074 -1.1032583164894 0.270522168277677 -25.8424606610449 7.83437332506157 -3.29859959294726 0.00105114186117825 NKX1-2 other 0.116548155376411 1 1 -1.1032583164894 -3.29859959294726 0.0625494463361257 1.49029455680722 4.98615486090235 0.298886536495885 0.76516837615302 -15.198211242327 8.48215099105021 -1.79178739665954 0.0738571920037868 ACVR2B-AS1 other 1 1 1 0.298886536495885 -1.79178739665954 0.0561091266801787 8.37587474376195 10.1765235145345 0.823058555487951 0.41092463261175 -39.2345137956223 22.2262429862526 -1.76523372933022 0.0782244560124211 MBNL1-AS1 other 1 1 1 0.823058555487951 -1.76523372933022 0.00449463484401463 353.851865960829 118.923949537173 2.97544663911639 0.00308752419306687 -64.4673046356766 266.628438207018 -0.241787054183704 0.80905832969126 C2-AS1 other 1 1 1 2.97544663911639 -0.241787054183704 0.0241532892194676 -270.985061538506 169.668375155565 -1.5971453801573 0.110956121329042 -478.473203504321 192.458868846451 -2.48610628531783 0.0132875779823937 EMX2OS other 1 1 1 -1.5971453801573 -2.48610628531783 0.705172187834191 -7.61409857813941 11.9269135291196 -0.638396393127992 0.523549323974914 -20.7040670363839 28.8910848792834 -0.716624769297947 0.473987589756846 PGA3 other 1 1 1 -0.638396393127992 -0.716624769297947 0.00043703688634528 16.5910209873543 13.5280298053135 1.22641812785168 0.220701772825569 -41.1767526701315 20.0625787633252 -2.05241575152858 0.0407243720513017 LINC01315 other 1 1 1 1.22641812785168 -2.05241575152858 0.649381275822553 1.99256706534228 2.14960695348781 0.92694483617541 0.354465656240957 1.78362989225693 2.88523463169134 0.618192320536286 0.536769886212906 GK3P other 1 1 1 0.92694483617541 0.618192320536286 0.142827333791848 -0.109631537666551 2.32030906687028 -0.0472486787350387 0.962336566290583 -3.2754694170473 2.97967726422273 -1.09926986267143 0.272254219285118 ZRANB2-AS2 other 1 1 1 -0.0472486787350387 -1.09926986267143 0.000157163958270999 5.27359116298662 1.82851759564054 2.88408007424137 0.00411913593622163 -7.61499505671227 4.29196112058249 -1.77424604808135 0.0767170649943601 PRRT3-AS1 other 0.760516394073366 1 1 2.88408007424137 -1.77424604808135 0.0297381544775182 21.5916165546518 11.0624558089314 1.95179234408508 0.0516012308911318 53.6663343730909 24.9810374026553 2.14828285583474 0.0322402823762463 HOXB-AS1 other 1 1 1 1.95179234408508 2.14828285583474 0.0206792089841489 7.2401104093848 8.50945711223109 0.850831059360792 0.395330226203262 -30.9959196531707 16.6834860601403 -1.85788027402889 0.0638599084482535 GOLGA6L17P other 1 1 1 0.850831059360792 -1.85788027402889 9.37915848089372e-09 -4.01301380851476 9.32729559577095 -0.430244090294971 0.667230674100231 87.014125063889 18.150501245056 4.79403427426507 2.24631985142192e-06 LRRC37A6P other 6.40971690584277e-05 0.0195609532661821 1 -0.430244090294971 4.79403427426507 1.17990033833347e-17 232.106317630066 25.3461852203115 9.1574458094019 2.06488284004806e-18 81.9260738450613 94.3706711399404 0.868130668728368 0.385799289401542 PSMG3-AS1 other 9.83682912068611e-14 1 2.01449969875089e-14 9.1574458094019 0.868130668728368 9.68325375706027e-31 12.8995580165341 3.91150520910967 3.29785014385044 0.0010538823410886 -12.9264995175832 4.7483399219119 -2.72231974335536 0.00674183351932125 PPP5D1 other 8.78561613378078e-27 1 1 3.29785014385044 -2.72231974335536 8.74063174967206e-10 46.0240315742815 10.9667896086857 4.19667315745989 3.2840133560865e-05 -33.8402185279826 18.5474031545626 -1.82452595902397 0.0687568019763067 THAP7-AS1 other 6.23556669021605e-06 1 0.279108295133791 4.19667315745989 -1.82452595902397 9.30023621746257e-33 5.58847008619318 7.05413876810876 0.792225708892804 0.428659906267134 -68.3961865493581 9.06598045737237 -7.5442680326692 2.67294186361585e-13 ZNF32-AS2 other 8.50785609173476e-29 2.57671595652568e-09 1 0.792225708892804 -7.5442680326692 0.948471423727018 -0.521058937108132 11.0408390270295 -0.0471937808197825 0.962380294603314 -3.02964367365976 14.2449532925836 -0.212681895927107 0.831674034850875 SETSIP other 1 1 1 -0.0471937808197825 -0.212681895927107 7.93013803693115e-09 -2.01600514335655 3.22218870637815 -0.625663276444977 0.531861690976148 -27.8957178003106 5.16313345217903 -5.40286592602745 1.07870662362743e-07 FBXW4P1 other 5.44403976235324e-05 0.000978063295642992 1 -0.625663276444977 -5.40286592602745 8.85961713431501e-19 65.20469195732 11.1431663374674 5.85154075445129 9.55040461921343e-09 12.7327302242747 14.3089112838822 0.889846192464487 0.374036958991334 FOXD3-AS1 other 7.48637647849619e-15 1 8.89333678141155e-05 5.85154075445129 0.889846192464487 9.48798184523565e-08 768.039083832141 172.130578916459 4.46195608396167 1.03392049691483e-05 -747.290980022624 397.272335497715 -1.88105466514902 0.0606275867169445 HSBP1 other 0.00061320826665758 1 0.0897442991322077 4.46195608396167 -1.88105466514902 0.0278021320351455 1.23043168427223 4.85891794300017 0.253231624552296 0.800208042305997 -8.77494104608646 6.18781657892242 -1.4180997342385 0.156872709769796 LINC00271 other 1 1 1 0.253231624552296 -1.4180997342385 0.00169402626112642 14.6574915771415 10.7630735465602 1.36183140566069 0.173952709856776 -34.7475973902131 17.4596501168262 -1.99016573400438 0.0471952871880534 KLF3-AS1 other 1 1 1 1.36183140566069 -1.99016573400438 0.188846053094994 1.96766256921216 1.45355170695265 1.35369286128619 0.176532495990988 -1.92743130530503 3.23922729630456 -0.595028112878624 0.552131955880822 LINC00852 other 1 1 1 1.35369286128619 -0.595028112878624 0.0397350355746683 2623.43025210086 1195.21877405779 2.19493728599515 0.028692240327002 5680.97203188967 2785.85714500659 2.0392187166066 0.0420279409114655 HLA-DPA1 other 1 1 1 2.19493728599515 2.0392187166066 0.0051116258600521 3.82825829212574 1.21429525188814 3.15265853685344 0.00172987210029158 2.64734889743566 2.36890196634498 1.11754261469937 0.264379218451501 LINC01516 other 1 1 1 3.15265853685344 1.11754261469937 5.59520762172378e-05 2951.23349844488 1024.94430170625 2.87940866009195 0.00417993547773361 -4919.74138924089 2389.02662230647 -2.05930789690872 0.0400566725742897 RPS18 essential 0.286306774003606 1 1 2.87940866009195 -2.05930789690872 0.265267961648577 5.82687477574536 26.2228672477494 0.22220586027813 0.824257441106583 83.0882221026205 53.0453094909605 1.56636322607901 0.117987413795432 FAM225A other 1 1 1 0.22220586027813 1.56636322607901 0.000386262036497061 -1.7132121069228 6.30129646327057 -0.271882479567322 0.785841374461185 -21.9277946420676 8.13801958673494 -2.69448781836433 0.00732259489896398 LINC00574 other 1 1 1 -0.271882479567322 -2.69448781836433 0.000711946068234811 122.073035820682 32.4734891741678 3.75915982313934 0.000193591592182858 19.6410410266593 72.8642600608442 0.26955658384863 0.787628348341046 LINC01354 other 1 1 1 3.75915982313934 0.26955658384863 2.95212812781357e-09 -0.683725229702911 2.9178859549775 -0.234322122335375 0.814845413306519 -13.2532632224379 2.07530908857166 -6.38616353362552 4.3826293425079e-10 DBIL5P other 2.06442319978003e-05 4.12405421129994e-06 1 -0.234322122335375 -6.38616353362552 0.16540483745463 42.3517032286947 23.4813714435361 1.80362988297062 0.0719779163893784 64.5203834404294 52.64669061413 1.22553540759716 0.221033631124641 CYP21A2 other 1 1 1 1.80362988297062 1.22553540759716 1.14905993644157e-26 67.7347881099867 25.1584637904546 2.69232607659001 0.00736754288071666 -193.787279045172 34.3243527634454 -5.64576644403769 2.96035330521291e-08 TRAF3IP2-AS1 other 1.02576580526139e-22 0.000271582812220232 1 2.69232607659001 -5.64576644403769 7.97576398895685e-08 1282.29514120131 220.178531388121 5.82388815620239 1.11557008098011e-08 1074.65242018902 516.939916055976 2.07887297306841 0.0382118011756999 TAPBP other 0.000517752866129908 1 0.00010373686183034 5.82388815620239 2.07887297306841 0.983319769190254 0.534258510174481 8.85420294185857 0.0603395374696863 0.951912797342567 2.89589815794353 16.094441992468 0.179931566394086 0.857289697035924 PPP1R2P3 other 1 1 1 0.0603395374696863 0.179931566394086 0.0894870058846497 8.83012480469148 6.09043286314821 1.44983534062423 0.147821727622526 -2.82575374703403 8.49093096297256 -0.332796693243255 0.739447345973765 LEF1-AS1 other 1 1 1 1.44983534062423 -0.332796693243255 0.0462537078024873 -11.5297497301477 5.62120831509474 -2.05111589605862 0.040849993253819 -25.1499586974248 11.7658973008673 -2.13753002038959 0.0331079832416363 ZBED9 other 1 1 1 -2.05111589605862 -2.13753002038959 0.000349511960172289 -0.883238958097423 1.87189581180301 -0.471841943621151 0.637276740670323 -11.326800925698 3.18288311063958 -3.55866066455137 0.000413877423709795 LINC01063 other 1 1 1 -0.471841943621151 -3.55866066455137 0.131156345608048 5.56748161399334 4.76038074827656 1.16954544360952 0.242821440873545 -2.47110581064056 6.58016159260869 -0.375538773001605 0.707442032197045 TMEM253 other 1 1 1 1.16954544360952 -0.375538773001605 2.62385132844045e-08 9.03519659823309 3.03816986482174 2.97389448261255 0.00310362493834457 -6.27994408556447 3.49811491727462 -1.79523664432876 0.0733084215644312 RFX3-AS1 other 0.000175168314686684 1 1 2.97389448261255 -1.79523664432876 1.5436308465887e-10 218.564057634777 70.7839066874537 3.08776483049807 0.00214604062215173 -317.41346846572 109.180278873089 -2.90724178159208 0.00383320672135346 TMA7 other 1.12932032736429e-06 1 1 3.08776483049807 -2.90724178159208 0.000726388663504748 -8.77358620333936 18.5489842606144 -0.472995506388377 0.636452545886587 39.5589791204566 22.4321423690894 1.76349536613887 0.0785157489153338 LINC00865 other 1 1 1 -0.472995506388377 1.76349536613887 4.11654654273221e-55 14.1427455962267 5.80158711718975 2.43773734851323 0.0151763035058352 -57.4156532007745 7.45023905492685 -7.70655180021445 8.7386085753157e-14 GNG12-AS1 other 3.96217604737975e-51 8.4397481620399e-10 1 2.43773734851323 -7.70655180021445 0.000983350990891917 8.27452454747194 3.16806543301525 2.61185405491974 0.0093167452326444 -2.69718977142823 4.79484398185901 -0.562518776759553 0.574052381350304 SEMA3B-AS1 other 1 1 1 2.61185405491974 -0.562518776759553 0.401206715742595 1.23316953317007 34.296299037447 0.035956344205642 0.97133358706542 -88.6120085995082 72.2704330537808 -1.22611702815682 0.22081493081489 C9orf172 other 1 1 1 0.035956344205642 -1.22611702815682 0.394540684660749 -2.69915090698605 8.81912052339202 -0.30605669803772 0.759733147649826 17.3339181081363 15.6486835709029 1.10769177672983 0.268712574994112 LINC01549 other 1 1 1 -0.30605669803772 1.10769177672983 0.00590576414360785 114.303081232494 54.6596223705716 2.09117949000018 0.0370875864945755 390.670703153056 127.402533184319 3.06642806377999 0.00230046757097813 HLA-DQB2 other 1 1 1 2.09117949000018 3.06642806377999 0.056676010965808 0.149201614695728 2.2365866009047 0.0667095182611646 0.946843605633458 -13.7611727337258 6.04408458293187 -2.27680015805644 0.0232830725833647 LINC01431 other 1 1 1 0.0667095182611646 -2.27680015805644 1.21474925714104e-07 9.32918170373485 7.72539367090075 1.20759952193441 0.227866681285744 -68.8750162415876 16.5472098357039 -4.16233412916395 3.80829844132959e-05 IDI2-AS1 other 0.000778168374124547 0.31243280412668 1 1.20759952193441 -4.16233412916395 2.73062793914967e-56 273.30215309068 30.4908066000612 8.96342811377549 9.29431020975462e-18 -50.7271774069593 40.4464131725026 -1.25418234716165 0.210447714568622 LINC00665 other 2.63177920775246e-52 1 9.05823473042686e-14 8.96342811377549 -1.25418234716165 0.112481094717686 -0.655500608831773 2.99071223572981 -0.219178763172383 0.826613837598438 -16.7195788233039 8.12943516575339 -2.05667164844833 0.0403150650307562 KIZ-AS1 other 1 1 1 -0.219178763172383 -2.05667164844833 0.826057429850951 2.87909521304562 37.6823050707388 0.0764044345918027 0.939132228334133 -44.4047493800255 82.781332849531 -0.536410176684864 0.591947425982247 TNF other 1 1 1 0.0764044345918027 -0.536410176684864 0.953354247226254 0.119367449649794 20.867718119906 0.00572019657175298 0.995438578670349 -6.63316778155564 28.5663221248614 -0.232202372869792 0.816489536040987 COL4A2-AS1 other 1 1 1 0.00572019657175298 -0.232202372869792 0.188706075017499 -52.5561452379802 44.6798494925518 -1.17628295159637 0.240123662813348 -157.099402846485 94.6157101803447 -1.66039447938447 0.0975540730552199 LYRM9 other 1 1 1 -1.17628295159637 -1.66039447938447 0.351271220817531 2.87880116916028 15.7397545628538 0.1829000037875 0.854961108839261 -9.61453444048375 19.1969262938627 -0.500837180562471 0.616737299204951 SEC1P other 1 1 1 0.1829000037875 -0.500837180562471 2.03198523260885e-08 79.693958069347 28.510724120507 2.79522742854593 0.00541477612727537 -259.730791383482 66.4552003769737 -3.90835916391995 0.000107668436954299 HCG25 other 0.000136630687040619 0.853703036610639 1 2.79522742854593 -3.90835916391995 0.325687518525697 -4.14839045327432 5.70917066486184 -0.726618750216448 0.467849457067602 -9.8705252433287 7.02271854763661 -1.40551343135494 0.160580819031442 LINC00327 other 1 1 1 -0.726618750216448 -1.40551343135494 4.94337868440223e-07 15.0300264539016 12.1648643071265 1.23552767005355 0.217297969357436 -49.6211095327608 16.1032543204978 -3.08143363727407 0.00219027884087983 NALCN-AS1 other 0.0030589627299081 1 1 1.23552767005355 -3.08143363727407 7.05789801333974e-10 426.693611793612 68.0276372437517 6.27235678147566 8.55928853919772e-10 67.2191646191647 143.350359695179 0.468915214179441 0.639364078399897 SNHG7 other 5.05486655715392e-06 1 8.07568873673305e-06 6.27235678147566 0.468915214179441 0.00141178132929339 1.75763724327113 1.77810188694472 0.988490736203677 0.323461871693622 9.45676138452014 2.78580661134084 3.39462234959967 0.00075025262651505 LINC01399 other 1 1 1 0.988490736203677 3.39462234959967 3.37937062086225e-05 2743.57353700261 612.094325523865 4.48227245801454 9.44630120044583e-06 1740.86194706202 954.424038403778 1.82399214291954 0.0688360569364101 GPX1 other 0.177822482069772 1 0.0821072500342751 4.48227245801454 1.82399214291954 0.0492307434117981 77.9712366765077 53.7666926541321 1.45017729057797 0.147724778045189 75.7758214132258 39.905995544771 1.89885806327553 0.0582400184115479 USP32P2 other 1 1 1 1.45017729057797 1.89885806327553 2.04716256676871e-52 21.2185362123404 4.23932696255607 5.00516624448964 8.11387889698112e-07 -26.6888715300619 5.56976338433232 -4.79174242933503 2.27083524684848e-06 ZNF529-AS1 other 1.96241003650449e-48 0.0197698916590628 0.00729681129205512 5.00516624448964 -4.79174242933503 0.0017346557399702 1.01950545382757 1.71445574321584 0.594652534987726 0.552384922326443 -4.899349912217 1.99577743700212 -2.45485785207411 0.0144846148148387 B4GALT1-AS1 other 1 1 1 0.594652534987726 -2.45485785207411 3.10100618311293e-08 16.4939163737805 6.29580244971854 2.61982749705209 0.00910295148122517 -5.46351838134212 8.08442376122204 -0.675808015847533 0.499519197980196 LINC01137 other 0.000206092870929685 1 1 2.61982749705209 -0.675808015847533 2.08669948418424e-05 -12.0295827188341 9.01104033199784 -1.33498267410008 0.182580248664566 -78.2364569175755 17.5791440575031 -4.4505270940187 1.08972486253092e-05 GPR158-AS1 other 0.112201831264587 0.0921580316242399 1 -1.33498267410008 -4.4505270940187 0.426450995249273 -10.8464707368672 81.9022514375195 -0.132431899569227 0.894703639407042 -79.2407552180495 61.336059748665 -1.29191140648343 0.197070632526432 PIRT other 1 1 1 -0.132431899569227 -1.29191140648343 0.00150672515383016 13.0557607026383 5.44809997560634 2.39638787120188 0.0169789107815768 40.1681304965519 11.5894006797775 3.46593681644315 0.000580883851127026 HIST1H2BN other 1 1 1 2.39638787120188 3.46593681644315 0.0034332092998235 -4.80437034815541 11.2383580803461 -0.427497532451596 0.669227552389321 71.3782082390465 24.2290242891865 2.94597947433248 0.00339142939062029 LINC01503 other 1 1 1 -0.427497532451596 2.94597947433248 0.337780649880619 -11.4929864025516 10.281284022064 -1.11785516068686 0.26424301389826 -17.4660332382073 11.8662757465201 -1.47190522210217 0.141766247098566 KRTAP5-AS1 other 1 1 1 -1.11785516068686 -1.47190522210217 0.0284274660249391 -3.96123523166238 6.24288230898336 -0.634520248117165 0.526074914847868 -22.7246594528655 9.43978256797633 -2.40732869525587 0.0164852621539652 CTXN2 other 1 1 1 -0.634520248117165 -2.40732869525587 6.89651098784065e-22 225.161735574497 52.234184807441 4.31062026534051 2.01251115250354e-05 -94.0951591916942 66.7433628407199 -1.40980548756958 0.15930679079647 UQCRHL other 5.99582665282866e-18 1 0.172572831327179 4.31062026534051 -1.40980548756958 0.023172944921607 6.43096983125953 8.84294450504806 0.72724303851374 0.467467393266147 -13.0980910175558 10.8615443095925 -1.2059142460974 0.22850455306419 LINC00463 other 1 1 1 0.72724303851374 -1.2059142460974 0.0530742948724797 33.7884046420527 18.6313370855167 1.81352548595766 0.0704381969937939 14.6791389570794 22.1993755628233 0.661241074801317 0.508806989247992 RPL13AP6 other 1 1 1 1.81352548595766 0.661241074801317 0.000338220569497368 115.550646197426 59.528312515827 1.94110401108219 0.0528867712280202 -313.018479644572 127.517543286963 -2.4547091449226 0.0144878346142363 TRIM26 other 1 1 1 1.94110401108219 -2.4547091449226 0.000739695073105693 18.7581727609234 6.77587148844043 2.76837788215504 0.00587316005609279 -13.3517660082329 12.9949634365224 -1.02745698927538 0.30477369274829 ZNF879 other 1 1 1 2.76837788215504 -1.02745698927538 0.109486761672046 7.77458594636436 3.90289428861706 1.99200525851782 0.0469908854536781 1.12333799500995 8.13185428127938 0.138140448187325 0.890192903499905 LINC01505 other 1 1 1 1.99200525851782 0.138140448187325 0.000657321902867781 -5.67292734874525 109.553695173483 -0.0517821634383206 0.958726258376145 -322.108825431888 127.571380846828 -2.5249301472925 0.0119299320807086 RNF219-AS1 other 1 1 1 -0.0517821634383206 -2.5249301472925 0.0406853337311656 12.5746738656343 6.26647776070337 2.00665738327346 0.0454016951218345 -1.22849231419894 10.4956841078095 -0.117047378863552 0.906876282179639 CCDC188 other 1 1 1 2.00665738327346 -0.117047378863552 0.00147083299533164 32.8998172595755 89.6441842712361 0.367004480290998 0.713997959851066 -309.574505149183 132.056730056658 -2.34425390524483 0.0200315091404886 ZNF37BP other 1 1 1 0.367004480290998 -2.34425390524483 1.96808194621659e-20 151.057742875132 18.9972058205047 7.95157689517097 1.60322205900133e-14 97.0871736971595 23.4085658829186 4.14750626684074 4.04302732967058e-05 PINLYP other 1.68723665249148e-16 0.330921786933537 1.55304120855459e-10 7.95157689517097 4.14750626684074 5.56349045977099e-05 12.9317297488505 5.87471867934169 2.20125089467255 0.0282403682094907 -45.2227546065538 13.2661833496526 -3.40887453569969 0.00071281793553638 SP2-AS1 other 0.284739441731079 1 1 2.20125089467255 -3.40887453569969 0.000350039658395508 190.686145265559 55.5253436161852 3.43421819383349 0.000651655189220057 454.987729750285 157.910797232262 2.88129588175702 0.0041577422673713 RPL13AP20 other 1 1 1 3.43421819383349 2.88129588175702 0.437131150074291 -4.35561326286607 3.60874287117586 -1.20696137639944 0.228101429354509 -6.58669296495426 6.62242398636985 -0.994604540348196 0.320480299261531 C5orf58 other 1 1 1 -1.20696137639944 -0.994604540348196 2.83437789764798e-06 75.749707191379 32.7350492237641 2.3140245390677 0.0211283251821509 -141.137185021584 56.2145685580264 -2.5106869738918 0.0124088995186371 MAPKAPK5-AS1 other 0.0165811107012407 1 1 2.3140245390677 -2.5106869738918 3.79243274020391e-21 330.906223709576 34.9392246478561 9.47090918715853 1.75830496274384e-19 -98.576925584326 111.069187951985 -0.887527201755907 0.37528333096855 JRK other 3.27969583372834e-17 1 1.71856727058583e-15 9.47090918715853 -0.887527201755907 0.0501207126631448 -13.6899129614712 9.2273404868541 -1.48362499259399 0.138641021669694 -45.73797080378 19.0151175039869 -2.4053477867907 0.0165785571152134 CHL1-AS1 other 1 1 1 -1.48362499259399 -2.4053477867907 0.134390705079412 6004.42526259087 3014.43494157085 1.99189081170281 0.04700349233514 6678.73321534385 6668.83968970701 1.00148354527881 0.317146038688957 HLA-B other 1 1 1 1.99189081170281 1.00148354527881 5.21358352986738e-17 -0.248120537754727 1.70400330221071 -0.14561036204145 0.884295972806644 -10.8611194292529 2.18810626534334 -4.96370747677039 9.92238610490331e-07 LINC01135 other 4.31736852108318e-13 0.00874559111286177 1 -0.14561036204145 -4.96370747677039 7.64304382856468e-09 90.0355620309694 195.985304751932 0.459399556231686 0.646175707526714 -651.403384959292 244.39873978124 -2.66533037585365 0.00797617956977186 APOC2 other 5.25000680584108e-05 1 1 0.459399556231686 -2.66533037585365 0.000243004089537088 74.3100183486246 51.7815284320557 1.43506807540703 0.151987936849064 -178.051021938569 79.2043212461127 -2.24799631052085 0.0250776955008505 SEMA3F-AS1 other 1 1 1 1.43506807540703 -2.24799631052085 0.000205144396614851 -5.3599498486444 2.6337758982253 -2.03508197195367 0.042445603053154 -11.2043074652925 3.22165473599514 -3.47781136821032 0.00055617947090817 C19orf81 other 0.974025595127312 1 1 -2.03508197195367 -3.47781136821032 0.00174930051906878 -16.7882375137281 28.7895094119331 -0.583137325249783 0.56010166197153 -95.457233224604 38.2018419899816 -2.4987599616175 0.0128290253317817 ANKRD65 other 1 1 1 -0.583137325249783 -2.4987599616175 0.000526961472264174 17.3910423008081 9.13700140944322 1.90336430098765 0.0576482873484108 -41.9689140129643 18.5919446843321 -2.25737085202994 0.0244766879872663 ZSCAN31 other 1 1 1 1.90336430098765 -2.25737085202994 0.752640095023664 10.3092852264474 32.0392890220842 0.321770099809061 0.747780371903451 -20.5648183719645 54.2783465128635 -0.378877023586022 0.704962776534979 C12orf75 other 1 1 1 0.321770099809061 -0.378877023586022 2.73232215123048e-13 130.517919470716 18.9416446379748 6.89052729925306 1.94852927016862e-11 -61.3301243647969 54.2336243318141 -1.1308505584942 0.258738231555551 HGH1 other 2.13121127795977e-09 1 1.86240427642717e-07 6.89052729925306 -1.1308505584942 6.06524521180634e-42 79.1767604369335 11.8124477766029 6.70282416771908 6.31121382552964e-11 -6.63123235736508 14.4070028800013 -0.460278408534925 0.645544812372004 NUCB1-AS1 other 5.69041305771671e-38 1 6.0152178971123e-07 6.70282416771908 -0.460278408534925 7.49436016160116e-09 19.1307634730537 41.4756097166806 0.461253339100636 0.644846347201895 -275.847786569718 61.8528181130369 -4.45974484243551 1.0447343695395e-05 PPP1R3E other 5.15012430305232e-05 0.088426317037823 1 0.461253339100636 -4.45974484243551 0.0102287094920347 9.66370299986404 9.91168289184603 0.974981050676471 0.330107813340914 -31.5394175225858 16.8611672138945 -1.87053583672403 0.0620761042277706 ITGA9-AS1 other 1 1 1 0.974981050676471 -1.87053583672403 0.00301560004835957 12.1904816645592 3.55902325858584 3.42523236822089 0.000672172329379159 10.1926001346623 6.99372262000089 1.45739267747239 0.145724581892303 SSR4P1 other 1 1 1 3.42523236822089 1.45739267747239 4.6587344697736e-08 5.68276992267476 6.98680742344847 0.813357171345925 0.41645622938311 32.6933530977864 8.3757291712927 3.90334410642609 0.000109847683610092 RPEL1 other 0.000306218616698219 0.869811394573245 1 0.813357171345925 3.90334410642609 0.27741692846484 -1.98092457412436 4.71931498636277 -0.419748327850243 0.67487654656677 6.09705899799711 5.55460309708713 1.09765880503585 0.272960721740412 SPAAR other 1 1 1 -0.419748327850243 1.09765880503585 1.57065992193032e-14 24.9945771773083 7.76788457351271 3.21768133148321 0.00138891907211007 -36.0973705181447 9.03965138944616 -3.99322595120079 7.65112146968567e-05 SMIM27 other 1.2532295517082e-10 0.614079009156972 1 3.21768133148321 -3.99322595120079 0.121234034147315 3.26109138895599 1.98290018160828 1.64460693443025 0.100768368768721 -0.0941025593368524 3.26208049406429 -0.0288474056688921 0.976999431537887 LINC01664 other 1 1 1 1.64460693443025 -0.0288474056688921 0.0549857180540424 -9.886243365504 43.7920565963598 -0.225754260792716 0.821498095593257 108.601951084384 64.9452726905864 1.67220717667609 0.0951992481963329 NFAM1 other 1 1 1 -0.225754260792716 1.67220717667609 1.75243656700554e-23 8.8082720446646 4.80427509726642 1.83342374579599 0.0674195717395617 -33.3960429963582 6.2744603807612 -5.32253627718447 1.6391851531696e-07 FAM21EP other 1.53828881851746e-19 0.0014787089266743 1 1.83342374579599 -5.32253627718447 7.08024666831002e-07 61.08423598696 41.9082129917936 1.45757195609657 0.145675149797968 -90.6576476420832 49.194047338599 -1.84285808033019 0.0660252945005259 DICER1-AS1 other 0.00433523503500623 1 1 1.45757195609657 -1.84285808033019 0.109372158920174 -8.05333472310134 5.40438890730654 -1.49014714914641 0.136906937819137 -20.4292620334698 9.90420243609972 -2.06268623498722 0.0397328026716851 ANKRD34C other 1 1 1 -1.49014714914641 -2.06268623498722 0.361738232322625 -0.615421227986688 2.68689153831201 -0.229045802263129 0.818941211035118 -7.6631699190861 5.58840004798024 -1.37126366281808 0.171001366324832 BHLHE40-AS1 other 1 1 1 -0.229045802263129 -1.37126366281808 6.77228737975799e-06 61.8142783089511 13.4574028867308 4.59332895278783 5.71398887620117e-06 108.421955995853 31.3676496468956 3.45648963873145 0.000600807755261634 B3GALT4 other 0.0382634236956326 1 0.0500888264887794 4.59332895278783 3.45648963873145 0.105151016807434 -14.3442745789665 19.9903520817712 -0.717559876899153 0.473411217978772 -87.0373531445419 40.9832928066926 -2.12372767495951 0.034252795662329 GSN-AS1 other 1 1 1 -0.717559876899153 -2.12372767495951 1.97704583928877e-05 7.3977656158694 3.27645578242989 2.25785608203235 0.0244484170354236 -7.50061891686412 4.5357510510391 -1.65366635700736 0.0989150811355494 ARHGEF7-AS2 other 0.106661623029629 1 1 2.25785608203235 -1.65366635700736 5.11720608988806e-08 -4.05954219912889 18.9722221516758 -0.213972942477395 0.830667956924164 -88.0215878770856 22.7121713848968 -3.87552499430409 0.00012271450362575 CPB2-AS1 other 0.000335432859192163 0.968585577118042 1 -0.213972942477395 -3.87552499430409 4.07600725266387e-18 230.774942808959 41.5603390274653 5.55276853387675 4.88922086875541e-08 -199.103366339939 67.1595122867575 -2.96463389266152 0.00319626625549837 TTC28-AS1 other 3.41528647700706e-14 1 0.000449857212134185 5.55276853387675 -2.96463389266152 2.85749426303788e-10 40.8037351377727 15.1633588433622 2.69094305287346 0.00739890753563903 -81.94202447292 23.946640808647 -3.42185883722494 0.000680620927820972 MORC2-AS1 other 2.07368358668659e-06 1 1 2.69094305287346 -3.42185883722494 3.0025285764411e-06 22.4014976745346 41.7269555116176 0.536859145362223 0.591640015209149 -138.040368743754 48.5117039341424 -2.84550649738364 0.00464406557432571 MYCBP2-AS1 other 0.0175287618292631 1 1 0.536859145362223 -2.84550649738364 2.92154931263627e-09 72.4182348922429 11.2955417228934 6.41122282302478 3.7413558761072e-10 -1.64830130549211 8.45454157528749 -0.194960458921873 0.845514303631591 COX10-AS1 other 2.04362374418907e-05 1 3.54268987908591e-06 6.41122282302478 -0.194960458921873 1.79230184919313e-12 223.369886500505 37.9171991564092 5.89099119845587 7.6712148212541e-09 -193.347555013956 89.0228199153545 -2.17188755869334 0.0304012507605633 ZBTB22 other 1.3725447561121e-08 1 7.15264069933732e-05 5.89099119845587 -2.17188755869334 8.52912322762532e-33 95.3198400901546 18.586872460075 5.12834207556454 4.40138178426595e-07 -56.5210271363325 24.7453194858219 -2.2841098159479 0.0228439068230857 TMEM147-AS1 other 7.80500066559993e-29 1 0.00397972940933328 5.12834207556454 -2.2841098159479 5.86337482420548e-24 420.019211881304 64.9064687461004 6.47114563456418 2.60849843790195e-10 -119.47928509777 78.7168482128171 -1.51783624230925 0.129777110114236 ZBED5 other 5.16035618278324e-20 1 2.47363906866242e-06 6.47114563456418 -1.51783624230925 0.034584054146568 -1.6238559866881 4.63109496672874 -0.350641910467049 0.726025971683186 -12.9635806671207 6.29045228025278 -2.0608344344041 0.0399100513289906 GUSBP5 other 1 1 1 -0.350641910467049 -2.0608344344041 2.44381114195259e-08 -5.32818964553258 10.0087930875784 -0.532350863776496 0.594752950406602 -45.8410675015838 12.0544351818479 -3.80283827570897 0.000163344969790197 TLX1NB other 0.000163368774839531 1 1 -0.532350863776496 -3.80283827570897 0.0164248480705019 -21.9009643676526 12.4070669996236 -1.7652007818058 0.078226802505925 -59.9770703443991 20.8585114346993 -2.87542428577256 0.00423158996747014 TRHDE-AS1 other 1 1 1 -1.7652007818058 -2.87542428577256 0.00117801055021719 5.74663978494623 3.42931480156026 1.67573994149841 0.0945044253352244 27.8991935483873 7.75880569264641 3.59581031586207 0.0003602745360824 LINC00854 other 1 1 1 1.67573994149841 3.59581031586207 0.00101618133595159 32.3331225480075 9.88218306822845 3.27186030908085 0.00115372300398606 10.3617463349165 11.3852200729711 0.910105054492155 0.363272273192901 VLDLR-AS1 other 1 1 1 3.27186030908085 0.910105054492155 0.0253154682497522 -7.10212564950346 10.0854972673246 -0.704191916497087 0.481688339678436 -25.9748169579589 12.2281745911351 -2.12417779647909 0.0342162154263654 KCNMA1-AS1 other 1 1 1 -0.704191916497087 -2.12417779647909 0.00013967714293085 5607.11469826041 1723.84632896288 3.25267664759527 0.001231655385345 1995.40408256687 2178.12462505235 0.916111070788204 0.360112747323943 RPL13AP5 other 0.679668977501517 1 1 3.25267664759527 0.916111070788204 7.81111996389827e-06 50.5746060841707 12.1110893408419 4.17589241238766 3.5874645828758e-05 -24.222312947842 8.60886891556816 -2.81364639018242 0.00512035810174006 PITPNA-AS1 other 0.0438984941971083 1 0.304288745919525 4.17589241238766 -2.81364639018242 2.53126464210344e-10 10.5625554921354 7.31212251618925 1.44452660205701 0.14930750255744 -43.1520801623546 10.2521251591572 -4.20908635940822 3.11403401617257e-05 ARHGEF38 other 1.83896376248815e-06 0.257001227354722 1 1.44452660205701 -4.20908635940822 8.37159982211526e-12 26.449870358348 10.5200885907739 2.51422505904985 0.0122885344546869 -27.8453965691383 12.2073574063231 -2.28103394062298 0.0230279958630285 INTS6-AS1 other 6.31720922576818e-08 1 1 2.51422505904985 -2.28103394062298 7.14604014678834e-69 34.2866168740863 11.8178885007202 2.90124728051011 0.00390455020292445 -133.466725463973 15.106865656073 -8.83483897338552 2.46093836057403e-17 ELOA-AS1 other 6.9716767672067e-65 2.40532115362506e-13 1 2.90124728051011 -8.83483897338552 2.89875202015132e-08 25.216168516937 9.0309287596834 2.7922010225027 0.00546424217655607 -38.1309972095868 7.05458738325605 -5.40513500478995 1.06598384339598e-07 LINC01563 other 0.000193056884542078 0.000966740747575814 1 2.7922010225027 -5.40513500478995 2.28518685047494e-05 87.7731974823956 20.6461909810571 4.25130221661359 2.60039404501775e-05 0.897675577990644 40.7984719812034 0.0220026764336718 0.982455863364955 CBR3-AS1 other 0.122280348368914 1 0.222047647504066 4.25130221661359 0.0220026764336718 7.2171265603909e-16 1.43929642158099 4.80175538852021 0.299743803072931 0.764515429021701 -23.5836968307586 5.57603309414757 -4.22947576396404 2.85618865026575e-05 EDRF1-AS1 other 5.87979300875047e-12 0.236378172695993 1 0.299743803072931 -4.22947576396404 2.73748489817053e-18 33.7034304430303 33.5088599301058 1.00580653932513 0.315065235557451 -330.113926170362 50.6111580725417 -6.52255231340893 1.91449981453231e-10 NDUFA6-AS1 other 2.29948731446324e-14 1.80709637493705e-06 1 1.00580653932513 -6.52255231340893 2.70217173248822e-27 310.234760612153 45.2159033655629 6.86118682853591 2.34005355120291e-11 -200.299783659443 67.4245873217769 -2.97072316814537 0.00313443940981408 PRMT5-AS1 other 2.4208756551362e-23 1 2.2349851467539e-07 6.86118682853591 -2.97072316814537 0.0341476835765871 33.5741660376359 12.9514767651905 2.59230407824015 0.00985375724337275 36.6330300742919 17.6085723810357 2.0804088645906 0.0380714319187066 HAND2-AS1 other 1 1 1 2.59230407824015 2.0804088645906 1.92598765379519e-19 -1.26470969261568 5.12476566128039 -0.246783907051801 0.805191088447296 34.6309327523261 6.21273336040984 5.57418623065478 4.35425111339873e-08 ZNF503-AS2 other 1.63651170942977e-15 0.00039815272180918 1 -0.246783907051801 5.57418623065478 0.879657108289608 -20.5047275375044 58.3244611816975 -0.351563085574443 0.725335014577965 -62.6306024621028 134.611148444137 -0.46527054546373 0.641968962901291 B3GNT9 other 1 1 1 -0.351563085574443 -0.46527054546373 0.0790687133664252 -144.056134927643 98.7412619916356 -1.45892539777186 0.145308986533847 -337.345403899722 149.315931128001 -2.25927268009019 0.0243617450629036 CKMT1B other 1 1 1 -1.45892539777186 -2.25927268009019 5.53420073054778e-33 76.4236562550587 10.1242734296652 7.5485571173067 2.59624811732109e-13 -109.291930620287 21.5616933890928 -5.06880088906068 5.92734435814847e-07 PITRM1-AS1 other 5.06822102903566e-29 0.00526644546221491 2.50537943321485e-09 7.5485571173067 -5.06880088906068 0.0612048005131499 8.64469101167867 8.31391725164279 1.03978554874004 0.299013172298071 -2.80369185399996 10.6758797968668 -0.262619278911588 0.792967517302374 FOXD2-AS1 other 1 1 1 1.03978554874004 -0.262619278911588 0.195692778109475 45.3510213185138 25.7378663699101 1.76203499803438 0.0787609000122262 29.9778451015744 42.3415120049159 0.708001289564102 0.479321038453856 CECR7 other 1 1 1 1.76203499803438 0.708001289564102 2.0341257734425e-06 414.789482778493 102.051791878242 4.06449975198257 5.70824686370895e-05 -340.728717889638 237.87092356661 -1.43241011881902 0.152741393723732 RGL2 other 0.0120379563272327 1 0.480291891112471 4.06449975198257 -1.43241011881902 0.000186996921329132 108.467806937655 44.6741818796378 2.42797522806106 0.0155852698522116 -96.7503949593894 73.4937535683961 -1.31644378279509 0.18871358480714 DGCR5 other 0.894406274717239 1 1 2.42797522806106 -1.31644378279509 2.09557795919824e-05 340.42810990039 74.2315115511934 4.5860323033516 5.90771831888472e-06 139.755260510395 174.282347638787 0.801889935520309 0.423052458223998 KIFC1 other 0.112658271086498 1 0.0517161661635168 4.5860323033516 0.801889935520309 6.77180512347586e-15 6.95072871715547 2.01019787069998 3.45773359850149 0.00059798934339617 -3.08169231425368 2.59356872307162 -1.18820538158093 0.235396380030848 AMY1A other 5.43369643107703e-11 1 1 3.45773359850149 -1.18820538158093 8.11052474825215e-08 59.1874408237037 34.3159552869428 1.72477905186642 0.0852759874449723 -199.204115553684 55.1627445014554 -3.61120747986765 0.000340212617142551 FAM200B other 0.0005262108456666 1 1 1.72477905186642 -3.61120747986765 2.40536706570995e-42 93.6010260208983 25.5731752503171 3.66012531117885 0.000282845070848331 -163.370933960959 32.8384486798505 -4.9749893959273 9.39076728359197e-07 NFIA-AS2 other 2.25960182152793e-38 0.00829016935795499 1 3.66012531117885 -4.9749893959273 1.08780936666003e-05 0.0928350833846997 4.43111386827212 0.0209507329634253 0.98329451887276 -21.9085812373416 6.51993904097423 -3.3602432629597 0.000847090250663068 LINC01238 other 0.0602102484446327 1 1 0.0209507329634253 -3.3602432629597 0.0283883487317564 27.4903408736837 10.7232917150256 2.56361027977667 0.0106925124477446 7.95050254164131 21.1900547167826 0.375199717410096 0.707693974416429 LINC00649 other 1 1 1 2.56361027977667 0.375199717410096 0.462315392151093 25.2488760729061 20.9289528791548 1.20640895025637 0.228315541659459 23.3441786302625 24.3735375206813 0.957767357752424 0.338712080120877 PTENP1 other 1 1 1 1.20640895025637 0.957767357752424 0.0110509093362576 3.98420413122733 3.17694288542265 1.25410001845132 0.210476068185833 -7.71362622268632 5.48718342458185 -1.40575330289312 0.160507967782664 SPATA3-AS1 other 1 1 1 1.25410001845132 -1.40575330289312 0.385729100677845 36.9288157360789 38.6831906974491 0.954647614900965 0.340284908651659 -75.8910363033952 90.575825598503 -0.83787297330083 0.402561117558503 LRRC37A2 other 1 1 1 0.954647614900965 -0.83787297330083 5.14908212388249e-06 -2.39955971624212 3.70224048736071 -0.648137181912983 0.517235843497617 -16.4610935625045 4.70013847596271 -3.50225714554779 0.000508719435027097 LINC01625 other 0.0294784951592272 1 1 -0.648137181912983 -3.50225714554779 0.751318525622886 9.31931862301048 20.3854764621167 0.45715481020662 0.647786948679801 -9.08653099521117 35.4393917545174 -0.256396358553555 0.797765457184031 GOLGA2P5 other 1 1 1 0.45715481020662 -0.256396358553555 0.0150290867799081 21.864110396805 7.884247203085 2.77313861851641 0.00579734948665389 3.39983474281843 18.4005971948086 0.184767630464605 0.853499850038844 LINC01410 other 1 1 1 2.77313861851641 0.184767630464605 7.88145037806349e-18 8.3610570342849 12.8607955819733 0.650119736449617 0.515956494470025 -75.1425950642265 14.6959638353426 -5.11314507208535 4.74903469553256e-07 CD81-AS1 other 6.58022292064521e-14 0.00423656375314073 1 0.650119736449617 -5.11314507208535 0.00101408017835078 22.1982031086763 16.769339619917 1.32373746443249 0.186285473563145 -84.0976026308376 33.4999584119462 -2.51037931440679 0.0124220528573557 PAXBP1-AS1 other 1 1 1 1.32373746443249 -2.51037931440679 3.7067772161457e-16 298.581193806133 37.7479373599504 7.90986778850915 2.12155556996397e-14 -14.4372764756571 77.3863115139393 -0.186561113887133 0.852091135446194 TMEM250 other 3.03547986230171e-12 1 2.0547265695101e-10 7.90986778850915 -0.186561113887133 0.0597169417165561 2.92392434186205 1.75162427749738 1.66926456742172 0.0957794938038105 2.184617860296 1.32008745781788 1.65490388334361 0.0986603259491572 SNORD10 other 1 1 1 1.66926456742172 1.65490388334361 0.00392754779836958 399.763199754831 127.656958935806 3.13154255817623 0.00185623323239326 134.858317280563 228.137944883259 0.5911262037079 0.554742889371937 TXNDC5 other 1 1 1 3.13154255817623 0.5911262037079 0.0625717228063099 -30.4334468383093 96.1184878752044 -0.316624278128705 0.75167990428382 -323.639938898266 155.065369593438 -2.08711938550051 0.0374562087133543 CASTOR1 other 1 1 1 -0.316624278128705 -2.08711938550051 3.11667984072119e-20 85.8564591562268 14.0861704938386 6.09508873925537 2.412969101361e-09 16.6266645665221 18.5272982154641 0.897414419153919 0.369994225102316 ALKBH6 other 2.66850127962548e-16 1 2.26674317381852e-05 6.09508873925537 0.897414419153919 2.06586255066346e-05 4.30792342992616 8.64608091618537 0.498251574521096 0.618557972020101 -52.7458031602955 14.2635768111005 -3.69793662969912 0.000245100727659282 ASB14 other 0.111143405225694 1 1 0.498251574521096 -3.69793662969912 0.00194048321575191 -104.852385819293 137.024308050359 -0.765210109878877 0.444561392396067 -1015.35858523291 288.903354618292 -3.51452680975071 0.000486731804212315 PCDHA13 other 1 1 1 -0.765210109878877 -3.51452680975071 0.493790347059795 -0.531414944357084 5.70659444217557 -0.0931229562117767 0.925848557553971 -12.4684079037029 11.3347893342077 -1.10001231924743 0.271932342813178 ST3GAL6-AS1 other 1 1 1 -0.0931229562117767 -1.10001231924743 0.174515950276852 1.49923276676101 6.04412888288755 0.248047782535828 0.8042136837086 -17.8320770942941 11.7024471758661 -1.52379043684718 0.128282734584607 MYLK-AS1 other 1 1 1 0.248047782535828 -1.52379043684718 0.0805842781141947 2.35656750802971 1.99502508601869 1.18122199291865 0.238155528375629 -3.2518203373299 3.38232150108727 -0.96141668859231 0.336873141082421 PSMD6-AS2 other 1 1 1 1.18122199291865 -0.96141668859231 0.154787248528027 70.9074801351705 56.1617378202109 1.26255851202761 0.207419666312725 60.697888557693 42.3255184677169 1.43407312550676 0.152264916043813 TNFSF12 other 1 1 1 1.26255851202761 1.43407312550676 0.0700144182715097 -24.7023091743246 12.8322489222329 -1.92501792351657 0.0548743888485745 -11.0832536349398 9.52418017626872 -1.16369634234302 0.245180615253391 CDRT4 other 1 1 1 -1.92501792351657 -1.16369634234302 0.00133353999735852 -18.1443173973017 23.2987417538144 -0.778768123576081 0.436536841166138 84.3860120345108 36.2302261708066 2.32916050914711 0.0203045122495994 APOBEC3G other 1 1 1 -0.778768123576081 2.32916050914711 0.236392706335379 -1.2716212960731 2.63354300080947 -0.482855717822814 0.629439983483325 -9.2605396290049 5.49688205533078 -1.68468952686081 0.0927624681668089 HLTF-AS1 other 1 1 1 -0.482855717822814 -1.68468952686081 0.103028783004144 7.41207386363641 3.83969951403219 1.93037862378266 0.0542066590670676 11.1115678267046 5.8671258620624 1.8938690063824 0.0589025558957827 TLR9 other 1 1 1 1.93037862378266 1.8938690063824 1.09123333900828e-10 2.75538014347047 2.14616223313288 1.28386386682813 0.199868334989778 -8.7661004293448 2.59517216400057 -3.37784928142551 0.000795818057531827 SUGT1P3 other 8.02165627504983e-07 1 1 1.28386386682813 -3.37784928142551 1.31987656514829e-22 364.058131137627 36.3500310399604 10.0153458118759 2.17606907881476e-21 -177.885286983143 137.208021682583 -1.29646419212036 0.195501371868458 GET4 other 1.15317615497006e-18 1 2.13037162815965e-17 10.0153458118759 -1.29646419212036 2.99547273205495e-14 224.852790903799 45.8079663132598 4.9085957967689 1.29755951416645e-06 -136.816345802049 69.9536463610548 -1.9558143559221 0.0511237893521046 ADSL essential 2.38140082198368e-10 1 0.0115949918185914 4.9085957967689 -1.9558143559221 0.000854526190508734 11.477587572668 30.3006005952442 0.378790761476506 0.705026791616783 -53.0259173812389 37.5978846417636 -1.41034310537614 0.159148154189308 LILRA4 other 1 1 1 0.378790761476506 -1.41034310537614 2.45503809584686e-17 -6.42260864039854 25.157999930992 -0.255290907783435 0.79861825557263 -146.30625923656 32.0798466737868 -4.56069072662091 6.62688585222277e-06 LILRA2 other 2.03940014621998e-13 0.056580351406278 1 -0.255290907783435 -4.56069072662091 3.45226687636491e-18 149.616507508173 49.6877695371712 3.01113350230474 0.00275331337645412 -143.610338904849 64.1074427891639 -2.2401507946145 0.0255819081700335 AMY2B other 2.89541622920725e-14 1 1 3.01113350230474 -2.2401507946145 2.86843202000144e-13 449.428197412268 69.8620382171414 6.43308166897993 3.28112131814952e-10 -287.654927710958 157.769583507943 -1.82325972671706 0.0689455142144863 LY6G5B other 2.23651644599512e-09 1 3.10820622468304e-06 6.43308166897993 -1.82325972671706 0.0308054782408501 197.258263305324 84.4139640027674 2.33679659089172 0.0198996734994468 402.934834446598 196.754978970961 2.0479015908719 0.0411654423591378 PSMB9 other 1 1 1 2.33679659089172 2.0479015908719 0.561509792444606 3.9182199609366 6.91793457930251 0.566385807211789 0.571422959085559 -9.25734850859641 14.9556396719839 -0.618987132054137 0.536248109788142 ERICH6-AS1 other 1 1 1 0.566385807211789 -0.618987132054137 0.00028755520996981 -2347.06125678104 3653.72499707851 -0.642374907432207 0.520966639254734 -30660.1919283249 7703.21829149821 -3.98017955198849 8.06198579824889e-05 PCDHGC3 other 1 0.646168161729649 1 -0.642374907432207 -3.98017955198849 6.86845575845197e-43 102.463599623238 37.0553499392703 2.76514996596078 0.00593168703156304 -206.534588359278 46.0477634281045 -4.48522518757605 9.33239228058613e-06 ZNF542P other 6.45978264082408e-39 0.0791573513239315 1 2.76514996596078 -4.48522518757605 0.108990636797273 -10.3794399214876 47.849104561849 -0.216920254130803 0.828371957821057 -378.451103306523 180.612802475932 -2.09537252131922 0.0367141327438871 COX19 other 1 1 1 -0.216920254130803 -2.09537252131922 0.269573593018701 -1.96377543853283 2.29420016633764 -0.85597388900364 0.392480243290508 3.84443467661189 4.55674796757904 0.843679462626591 0.399309071524656 B4GALT4-AS1 other 1 1 1 -0.85597388900364 0.843679462626591 0.00722515034892806 47.996468926557 70.7768572655408 0.678137893951461 0.498043177440968 -377.884180790958 149.220201831998 -2.53239290760647 0.0116777987025752 ACAD11 other 1 1 1 0.678137893951461 -2.53239290760647 1.07466089046635e-05 11.9588581277204 3.78519102104589 3.15938034863457 0.00169998211525813 -3.24427870838618 4.4701637461755 -0.725762833892127 0.468404386443403 CDKN2B-AS1 other 0.0595147201140263 1 1 3.15938034863457 -0.725762833892127 1.58999494719823e-09 150.670136495244 39.0025256525652 3.86308665847477 0.000128958270341237 -244.187479072699 79.6881166666656 -3.06428974967664 0.00231725153607533 ISY1 other 1.12285443171139e-05 1 1 3.86308665847477 -3.06428974967664 0.0976065701873176 16.6401242174179 15.238113826322 1.09200681968093 0.275430395570667 -20.8216646129719 24.4922698707921 -0.850132091587089 0.395716114548435 KRBOX1 other 1 1 1 1.09200681968093 -0.850132091587089 0.000170421722090276 -1574.14482003874 2904.91868484161 -0.541889460883334 0.588170842383346 -24131.8250243188 5932.12787440635 -4.06798800282669 5.62656815742803e-05 PCDHGC5 other 0.819898904976318 0.455695755070097 1 -0.541889460883334 -4.06798800282669 0.000410562825644973 -46.0688852348203 129.992471480836 -0.354396563970336 0.723220423516799 -787.948956540452 223.59625252535 -3.52398104906127 0.000472051849600965 ARHGEF25 other 1 1 1 -0.354396563970336 -3.52398104906127 0.243453878246306 -14.2269159741467 39.0253140539683 -0.364556091834962 0.715618736046529 -123.916963461286 76.2676613029905 -1.62476417060959 0.104932152538654 PLCXD2 other 1 1 1 -0.364556091834962 -1.62476417060959 0.000695517766157531 1057.57299064014 363.53032810714 2.90917403273283 0.00380832861422833 -175.953548844437 577.892910040061 -0.304474316586164 0.760911165889083 MIF other 1 1 1 2.90917403273283 -0.304474316586164 5.02977984687279e-16 15.4224045274931 8.679142622847 1.77695023548699 0.0762783819229399 -39.4945653660811 12.0254422163047 -3.28425056273876 0.0011055553986463 TPM3P9 other 4.11033609086444e-12 1 1 1.77695023548699 -3.28425056273876 5.86503540441176e-31 154.869488774681 19.1583953241283 8.08363571972214 6.2254434316589e-15 -140.578066104845 38.8190363506874 -3.62136928992458 0.000327417281578515 NSUN6 other 5.32486564366543e-27 1 6.0355674069933e-11 8.08363571972214 -3.62136928992458 0.10199173182738 24.37731092437 11.4991545131793 2.11992202526116 0.0345743572105046 29.4427709545356 26.8026259772642 1.0985032205244 0.272588284548539 HLA-DOB other 1 1 1 2.11992202526116 1.0985032205244 0.0334034223310464 -10.9919214139428 45.2266824771939 -0.243040630262581 0.808087959261849 -177.654188475056 76.6797752229184 -2.31683241061403 0.0209743853366396 PRICKLE2-AS1 other 1 1 1 -0.243040630262581 -2.31683241061403 0.11362428042211 -0.346883935489897 2.01163078717025 -0.172439166124444 0.863171932804911 -7.74224099257278 3.99550773095378 -1.93773645651903 0.0532977985450837 ARHGAP31-AS1 other 1 1 1 -0.172439166124444 -1.93773645651903 0.083629452059072 -3.50581277458606 5.94416447253216 -0.58979067466695 0.555636508809565 14.9578235890504 10.0785158119199 1.48412959489132 0.138497096074896 ADAMTS9-AS1 other 1 1 1 -0.58979067466695 1.48412959489132 0.810802708489552 -2.52967169702962 4.68047983558434 -0.540472726278458 0.58914641247463 -0.0450180263535346 7.80375681467976 -0.00576876335624023 0.995399850785528 LINC00877 other 1 1 1 -0.540472726278458 -0.00576876335624023 0.006486950074797 -6.88219544846076 3.30927918207057 -2.07966601480709 0.0381385765040934 -16.7870717319039 5.26973634512715 -3.18556197738938 0.00154822168184141 TDGF1 other 1 1 1 -2.07966601480709 -3.18556197738938 0.427836647969052 -20.8086003372672 21.1929306273592 -0.981865165471933 0.326709550286049 -52.5640809443497 44.235100786125 -1.1882889382008 0.235364977258911 WWTR1-AS1 other 1 1 1 -0.981865165471933 -1.1882889382008 0.1381209421521 -1.82010885133205 2.49167991746477 -0.730474584064543 0.465490676826289 -8.08894299627622 4.15417408419336 -1.94718440593394 0.0521513598577489 SUCLG2-AS1 other 1 1 1 -0.730474584064543 -1.94718440593394 0.142930441190151 0.662213085783223 1.60434996922632 0.412760992604729 0.679983704455739 -2.32764615992349 1.19075917754593 -1.95475811046916 0.051247356478369 CDRT1 other 1 1 1 0.412760992604729 -1.95475811046916 0.000453586473184281 333.69270251813 195.749258860646 1.70469458970307 0.0889637780563043 -525.506048714917 302.557753490475 -1.7368784724648 0.0831148825371152 PDXP other 1 1 1 1.70469458970307 -1.7368784724648 9.6896323947492e-08 120.489300368228 24.2649417397906 4.96557138526506 9.83259520541585e-07 -44.0787555421947 53.3057681839076 -0.826904048922451 0.408741695087554 RPP21 essential 0.000625853356376851 1 0.00882082115877856 4.96557138526506 -0.826904048922451 0.00533369000439485 83.4736694677881 47.9605411095112 1.74046554806768 0.0824795912223193 -209.321906198376 111.788083511022 -1.87248854818892 0.0618050507389088 EGFL8 other 1 1 1 1.74046554806768 -1.87248854818892 0.000758288545022246 -17.472690736038 16.1644969247504 -1.08093006651414 0.280323019600395 -100.35931693208 27.40493133946 -3.66208970527774 0.000280748813929885 PTPRG-AS1 other 1 1 1 -1.08093006651414 -3.66208970527774 0.0727324093916937 0.574538320005815 3.18655727178448 0.180300641414197 0.85700051640932 8.57308223781074 4.68073540944089 1.83156736877695 0.0676995832062202 ARHGAP8 other 1 1 1 0.180300641414197 1.83156736877695 0.0638438586687383 6.46192604351801 2.89671939780675 2.23077390527044 0.0262052585914333 1.34592399588171 6.16200912398452 0.218422915124052 0.827202045913375 GUSBP2 other 1 1 1 2.23077390527044 0.218422915124052 5.21962585727359e-08 880.098861583762 165.403946182343 5.32090607205666 1.65133608347789e-07 -140.172276707313 388.24198788027 -0.361043578703652 0.718240944781933 ARPC4 essential 0.000341989886168566 1 0.00150535797369844 5.32090607205666 -0.361043578703652 0.194491523165616 22.6058354431926 13.2513172912185 1.70593118754867 0.0887298046696191 19.0565276343538 16.9323521582656 1.1254507026687 0.261014412437473 CORT other 1 1 1 1.70593118754867 1.1254507026687 0.00281139735846585 5.45584372948121 4.61649969788601 1.18181394704294 0.237920761369296 -25.4873604727513 10.0824158796384 -2.52790211959253 0.0118251896149121 PAQR9-AS1 other 1 1 1 1.18181394704294 -2.52790211959253 0.454973191977164 -3.81904725783226 3.16004563471923 -1.20854180581211 0.227492461504471 -1.99436563924932 5.35771309528669 -0.372241962900889 0.709893153985067 ADAMTS9-AS2 other 1 1 1 -1.20854180581211 -0.372241962900889 0.00166031352328206 124.729332335422 52.0832739197614 2.39480591269239 0.0170484513585222 -184.575960748851 114.31316880327 -1.61465177355464 0.107106235172458 TMEFF1 other 1 1 1 2.39480591269239 -1.61465177355464 0.00032304602345258 589.388982364299 191.494308672309 3.07784072775176 0.00221628325916428 -409.02512263084 378.407581044622 -1.08091154384829 0.280332610660063 ATP5O other 1 1 1 3.07784072775176 -1.08091154384829 4.30931074798912e-05 70.5947515270345 118.088660087641 0.597811436548113 0.550276132685236 -665.290648195036 201.601116165689 -3.30003454766718 0.00104609907251376 PLEKHO2 other 0.223610134713155 1 1 0.597811436548113 -3.30003454766718 0.0011794641702262 -113.411787701309 56.3405111353988 -2.01297051474658 0.0447291198532146 -231.582113911946 67.9430696833316 -3.40847293169564 0.000713698467315829 HOGA1 other 1 1 1 -2.01297051474658 -3.40847293169564 0.0236530879629354 -67.4053430502516 391.604339117048 -0.1721261393636 0.863418228751907 -1559.63344532435 662.294419227978 -2.35489443976047 0.0189703376940156 PI4KA essential 1 1 1 -0.1721261393636 -2.35489443976047 0.70970063556659 -76.7947054197058 97.0918387452283 -0.790949130350876 0.429401746070392 -107.653278278277 200.838716066298 -0.536018554523818 0.592217823047861 AKAP2 other 1 1 1 -0.790949130350876 -0.536018554523818 2.12680406321685e-08 226.737750468747 104.606474626471 2.16753075063837 0.030736204520661 -469.957417489325 158.174113623043 -2.97113988328911 0.00313141651345643 HYPK essential 0.000142857428926276 1 1 2.16753075063837 -2.97113988328911 0.00279560642379852 125.443863200703 65.5509619253971 1.91368455192876 0.056311973389064 -153.195730844335 114.899345094316 -1.33330377748092 0.183125149256815 SDHAP2 other 1 1 1 1.91368455192876 -1.33330377748092 0.100511760737673 17.6333640446854 34.0709473447999 0.517548392952938 0.605036477905475 -109.370773128749 71.0239961188413 -1.53991297456347 0.124308651331616 AMACR other 1 1 1 0.517548392952938 -1.53991297456347 0.792280180291033 2.10721764312884 26.9547842354886 0.0781760159799192 0.937723822213926 25.9518155491213 43.485427956526 0.596793380418524 0.550954385652528 MTFP1 other 1 1 1 0.0781760159799192 0.596793380418524 7.31799885773093e-21 135.496845216352 36.1343950548306 3.74980250840641 0.000200724592659043 -87.3287450602732 46.3977749072201 -1.88217528178671 0.0604749400511689 SNHG3 other 6.30811501536407e-17 1 1 3.74980250840641 -1.88217528178671 0.00454752736130445 2.97509449811022 5.09192308167756 0.584277187692721 0.559338111316762 -26.4061878762425 10.0786681289987 -2.62000767742969 0.00910177164322709 TCP10L other 1 1 1 0.584277187692721 -2.62000767742969 7.83311692875585e-08 206.576858654545 50.8712567548792 4.06077757524108 5.79664530208052e-05 -35.1888868146942 75.0673373704227 -0.468764286137568 0.639471881949313 ARFGAP3 other 0.00050883927569198 1 0.487497869904972 4.06077757524108 -0.468764286137568 2.26954444405866e-27 208.60682898718 91.9176947531625 2.26949587397048 0.0237247196993157 -1245.54981030591 152.549876242405 -8.16486935936091 3.47946073031712e-15 C22orf39 other 2.03419268520977e-23 3.37925226128399e-11 1 2.26949587397048 -8.16486935936091 5.58932306199639e-43 448.982679945568 69.7060900582291 6.44108254487535 3.13347153928107e-10 -263.316778946202 92.4955337043755 -2.84680533643698 0.00462405803948525 MRPL20 essential 5.26011193364481e-39 1 2.96959097777667e-06 6.44108254487535 -2.84680533643698 0.000222623143084879 -175.858825760768 93.5478013588062 -1.8798819769826 0.0607876693244125 -734.418296383709 178.038456031241 -4.12505428745596 4.43647426517235e-05 ARPIN other 1 0.362459947464581 1 -1.8798819769826 -4.12505428745596 0.106703393572915 28.0300427939364 13.7933856442973 2.03213652664928 0.0427427554519343 11.8046202944804 22.1723521224035 0.532402707178401 0.594717081334806 LINC00960 other 1 1 1 2.03213652664928 0.532402707178401 0.062744145213609 318.71204481793 200.626683467388 1.58858253204258 0.112876228518419 1039.00249227896 467.62759400027 2.22185881588151 0.0268031257976783 HLA-DMB other 1 1 1 1.58858253204258 2.22185881588151 3.6734248877837e-05 184.695356070358 42.7106049471077 4.32434418334938 1.89605172647517e-05 28.4973723723717 88.3487548577667 0.322555449912676 0.747185848124768 GNG10 other 0.192267058626599 1 0.162738119683364 4.32434418334938 0.322555449912676 0.723691667941911 -7.45635548338631 16.9809228945093 -0.43910189862515 0.660804238671831 -31.5937026097587 40.4959907742168 -0.780168653877559 0.435713001446934 CNTF other 1 1 1 -0.43910189862515 -0.780168653877559 0.000823956120615108 21.963482884927 12.5415431194957 1.75125841179663 0.0806029687969482 -12.0688879385676 15.0750359121389 -0.800587674146062 0.423805411995247 CCDC169 other 1 1 1 1.75125841179663 -0.800587674146062 8.47394603435586e-05 -11.3452197971104 8.41603718553125 -1.34804772685831 0.178341371950777 -75.350599446665 17.3612295427401 -4.34016492099051 1.77064751773422e-05 LINC00882 other 0.423188864955732 0.147990719532226 1 -1.34804772685831 -4.34016492099051 0.23985268071756 -1.53551158819992 5.14636316689197 -0.298368292016059 0.765565212100025 5.73122055522183 7.6888713245484 0.745391659361454 0.456439400688862 ZNF702P other 1 1 1 -0.298368292016059 0.745391659361454 2.95717681130203e-39 483.733966167704 32.9109221110631 14.6982805445338 5.01887595471574e-40 143.340318851163 132.479118025158 1.08198424769059 0.279856212370462 AP5Z1 other 2.75549735277123e-35 1 4.94208715260859e-36 14.6982805445338 1.08198424769059 0.0367980612398919 4.17587811671996 5.81538737376268 0.718073938730256 0.473098057648345 -12.7163416898792 8.79399313993932 -1.44602588238623 0.148891691964727 STRC other 1 1 1 0.718073938730256 -1.44602588238623 0.0622968243343734 18.9324555684861 32.2789263864202 0.586526805192971 0.557825093526792 -132.154701484806 68.2376631229563 -1.93668269745227 0.0534299148779674 EIF4EBP3 other 1 1 1 0.586526805192971 -1.93668269745227 1.66036142997248e-14 403.312897669897 199.663772895318 2.01996031539157 0.0439958281500215 -1732.16407077673 328.468021221739 -5.27346334761579 2.1077858644164e-07 MICAL3 other 1.32413824040306e-10 0.00189763961373408 1 2.01996031539157 -5.27346334761579 0.00184575410356021 -139.644434374229 143.545884369069 -0.972820885725925 0.331181724083809 -1076.22330477054 302.647005714202 -3.55603486719062 0.000417718180173724 PCDHAC2 other 1 1 1 -0.972820885725925 -3.55603486719062 0.033708074067368 -4.29173693086015 4.22019951231475 -1.01695119350084 0.309739335664209 -23.0168634064081 8.80864256328011 -2.61298642112652 0.00928498514789149 LINC01998 other 1 1 1 -1.01695119350084 -2.61298642112652 8.90713993546233e-13 45.7367461106044 20.7179025012062 2.2075953928223 0.0277961265417295 -68.9142223250628 24.0979599234138 -2.85975337929353 0.00444468240213067 MRPS31P5 other 6.86473274826082e-09 1 1 2.2075953928223 -2.85975337929353 0.404179110651942 -10.0517124267125 11.4971881724999 -0.874275716453453 0.382447234113843 -30.5704454454448 23.7824367194919 -1.28542107800036 0.199324412454935 PALM2 other 1 1 1 -0.874275716453453 -1.28542107800036 1.46456292283229e-06 165.243200000001 33.2131443604172 4.97523505172654 9.38704514987767e-07 76.5520000000011 54.0081959177463 1.41741449976571 0.157074350520097 C4orf48 other 0.00875369258976861 1 0.00842675043104519 4.97523505172654 1.41741449976571 1.9867324816761e-08 40.029233223908 20.4430762578803 1.95808266422123 0.0508590915983132 -105.073462076892 30.9404471714112 -3.39599041651793 0.000746609972926995 NAT6 other 0.000133687228691984 1 1 1.95808266422123 -3.39599041651793 2.60279556019341e-14 11.3584730089681 3.8033038277622 2.98647531813182 0.00298047439144702 -7.76757216197502 4.90704422474976 -1.58294317438542 0.114156178822322 AMY2A other 2.07052386813385e-10 1 1 2.98647531813182 -1.58294317438542 0.0207944438467457 105.202082141007 39.3634088330574 2.67258566419325 0.00780979757549584 153.334532472133 78.635926562884 1.94992974807149 0.0518265404381125 IL10RB other 1 1 1 2.67258566419325 1.94992974807149 0.218641263039815 9.23946168902001 49.4117657202076 0.186989101772605 0.851755759826287 186.398065075467 110.781570695412 1.68257286753911 0.0931704733283882 CFB other 1 1 1 0.186989101772605 1.68257286753911 0.0214370234042992 2.81878266215882 15.5271132775303 0.181539389310566 0.856028390546642 -77.9033200122958 32.030487960625 -2.43216151149686 0.0154096351508351 DUBR other 1 1 1 0.181539389310566 -2.43216151149686 0.0223088598465651 -15.5497122597211 65.4672682199394 -0.237518880541667 0.81236584325256 -224.318504015133 98.9766500251427 -2.26637801903935 0.0239175435762861 PLA2G4B other 1 1 1 -0.237518880541667 -2.26637801903935 0.000398032660227752 132.399156707476 42.5369680945067 3.11256684804891 0.00197613801232933 70.3376618021476 54.6248077593947 1.28765051424919 0.198547576870993 CFAP57 other 1 1 1 3.11256684804891 1.28765051424919 1.35487707528231e-95 147.197733612822 20.6385405505018 7.13217745473011 4.11229989256261e-12 -215.365655005508 26.5018969314834 -8.12642414097006 4.56243747267453e-15 TTC4 essential 1.33387648061544e-91 4.42921429847243e-11 3.94863035683862e-08 7.13217745473011 -8.12642414097006 4.23918176786993e-05 65.5260749692032 14.5173290988531 4.51364534915585 8.19961857898575e-06 34.9229776500266 35.165961939058 0.99309035568393 0.321214226020096 RPLP0P2 other 0.2203102764762 1 0.0714760751530188 4.51364534915585 0.99309035568393 6.22338546138654e-28 6.56254629702601 15.9834230649763 0.410584533134596 0.681577985532075 -125.131187602992 20.5242725203259 -6.09674167398967 2.37784868894003e-09 TMEM35B other 5.59046715996353e-24 2.21544162348542e-05 1 0.410584533134596 -6.09674167398967 0.112930005842155 185.465970307799 93.7539146923061 1.97822107926357 0.0485299543880131 34.0670983079997 200.833324007292 0.169628713145049 0.86538045591538 HLA-L other 1 1 1 1.97822107926357 0.169628713145049 0.00158440471879909 1.81403336318547 1.99274753349588 0.910317705927909 0.363155662575227 7.63343817203775 2.61762507255196 2.91616941329027 0.00372558101388533 OSTCP1 other 1 1 1 0.910317705927909 2.91616941329027 4.03760530452081e-07 -8.8759898927096 18.3440588598249 -0.483861830172645 0.628726861339797 -125.412089060577 27.7334543379728 -4.52205078863407 7.90349560967205e-06 JMJD7 other 0.00251139049941194 0.0672508441426995 1 -0.483861830172645 -4.52205078863407 0.000726570259561307 -1.25170043366157 2.36024136114251 -0.530327302227967 0.596153772864536 -17.0083968116586 4.6879192073946 -3.62813351920186 0.000319124921081799 LINC02044 other 1 1 1 -0.530327302227967 -3.62813351920186 0.0289277616136793 -3.15129133242028 4.17092549144221 -0.75553767116819 0.450332542673966 10.1861670905889 6.52770855746206 1.56045065445587 0.119375638656352 APOBEC3D other 1 1 1 -0.75553767116819 1.56045065445587 0.0884079928197798 138.631582227208 67.8548241869652 2.04306154924559 0.0416457151845207 13.7203660675351 134.08638648753 0.102324825263384 0.918545786805362 MRPS6 essential 1 1 1 2.04306154924559 0.102324825263384 1.96165280612523e-07 116.44092806351 48.6693079310738 2.3924919628694 0.0171568357027285 -197.82156937782 74.3723808483249 -2.65987947570561 0.00810494854819119 ACY1 other 0.00124309938324156 1 1 2.3924919628694 -2.65987947570561 0.0427439186201334 14.869304417205 25.5349934893097 0.582310875600187 0.56065692163024 -73.7327264814675 41.0465480838878 -1.79631978627723 0.0731326399612365 FAM86DP other 1 1 1 0.582310875600187 -1.79631978627723 1.47223311179496e-56 651.459758655679 156.548377069455 4.16139579886317 3.81204053396448e-05 -1254.20692823145 201.175158442955 -6.23440258697294 1.07190328987332e-09 DDOST essential 1.41952716639271e-52 1.00362305030839e-05 0.322917953632131 4.16139579886317 -6.23440258697294 2.23188907978065e-06 6.68058370490474 8.29888471036686 0.804997772358428 0.421261743353341 -56.8612202816306 14.3211576842792 -3.97043462094192 8.39575993257767e-05 LINC01011 other 0.013177073127025 0.671996625003516 1 0.804997772358428 -3.97043462094192 2.68744175964835e-05 179.804500929503 40.6095117049941 4.42764498710756 1.20446469460993e-05 37.1522772772763 84.0025515667883 0.442275580733253 0.65850810525285 DNAJC25-GNG10 other 0.143079399283678 1 0.104342776494059 4.42764498710756 0.442275580733253 0.182123124451534 -7.07806141018423 7.59141190016616 -0.932377468548283 0.351657499025562 -23.5405734043608 12.7315397112301 -1.84899658158364 0.0651350416412907 FLNB-AS1 other 1 1 1 -0.932377468548283 -1.84899658158364 0.000203708014668411 107.906470106469 34.4474407548846 3.13249599220715 0.00184980341944711 -91.973576986078 72.5889244851677 -1.26704697222606 0.2058133214967 TMEM141 other 0.968631609748296 1 1 3.13249599220715 -1.26704697222606 8.55189660678939e-10 912.206266075542 311.328913182856 2.93004031250951 0.00356674549780844 -445.565456206846 359.392933861515 -1.23977244465951 0.215724903502252 IFITM10 other 6.10348860826559e-06 1 1 2.93004031250951 -1.23977244465951 0.513176531823845 25.1381102123868 24.5035909060968 1.02589495183468 0.305507332090952 4.69792489952423 41.5428472335316 0.11308625220402 0.910013986436359 LINC00698 other 1 1 1 1.02589495183468 0.11308625220402 1.22357848079355e-06 -2.82465847526687 4.53444412485271 -0.622933792432301 0.533652232083238 -16.8204537816369 5.6264728675871 -2.9895201092208 0.00295152462157962 LILRA6 other 0.00735860098349242 1 1 -0.622933792432301 -2.9895201092208 0.0532729957171925 93.1070338694419 48.8284055455512 1.90682109786657 0.0572007708466429 191.818620747493 82.5802404680535 2.3228149937599 0.0206485013362148 SCARF2 other 1 1 1 1.90682109786657 2.3228149937599 0.129799016404762 -55.3437683427905 67.2824638175039 -0.822558586631194 0.411206633525259 100.726602752233 105.300446083199 0.956563875072736 0.339315095218307 APOBEC3C other 1 1 1 -0.822558586631194 0.956563875072736 0.00140815667998927 72.0295171950263 40.8551342948836 1.76304688353568 0.0785898626434439 -99.7703035734294 65.6665901149303 -1.51934649566561 0.129396791235219 CCDC13 other 1 1 1 1.76304688353568 -1.51934649566561 0.201642034302838 -15.2343529518868 8.67208704738707 -1.75671125862106 0.0796657749808886 -7.07899767854699 19.7407984184464 -0.358597333729528 0.720069119869132 PTCHD4 other 1 1 1 -1.75671125862106 -0.358597333729528 0.108330806429412 1686.74957593456 1275.52653592259 1.32239473537454 0.186731594376296 -3183.95075472915 2947.9164184583 -1.08006819148363 0.280710276950093 C4A other 1 1 1 1.32239473537454 -1.08006819148363 0.443003192750997 59.6537271873624 2654.16267992741 0.0224755353688396 0.982078862334108 2721.69840024166 3149.45679698751 0.864180262083606 0.387961878440341 HBB other 1 1 1 0.0224755353688396 0.864180262083606 0.378022293609726 -0.363485399425862 5.1624304249952 -0.07040974298965 0.943899672221196 -9.69992294657465 8.27211552479182 -1.17260486963748 0.241591644645039 CRYBB2 other 1 1 1 -0.07040974298965 -1.17260486963748 1.20316361878989e-26 291.71627490661 107.455508295351 2.71476334284141 0.00689553956685472 -675.3468517666 129.366266561389 -5.22042468811701 2.76843392818232e-07 N4BP2L2 other 1.07394384613185e-22 0.00248494629393645 1 2.71476334284141 -5.22042468811701 0.0456301342876357 42.1969451750076 224.967925259614 0.187568717301865 0.851301808851784 -609.546170791457 340.123482970438 -1.79213197944476 0.0738034800154502 MIR4712 other 1 1 1 0.187568717301865 -1.79213197944476 0.000651978463780669 33.0938648897061 26.2298350165041 1.26168787828376 0.20773723441334 -144.386029411764 56.3007308671981 -2.56454982355986 0.0106655852297424 LIFR-AS1 other 1 1 1 1.26168787828376 -2.56454982355986 9.91931380722888e-05 14.8931991756583 37.0833713182332 0.401613948415084 0.688165393570118 -278.784155655231 75.0250239764753 -3.71588226006627 0.000228901620896619 LINC00847 other 0.492295544252769 1 1 0.401613948415084 -3.71588226006627 0.257623165069413 -100.113539185144 132.055882506683 -0.758114953190949 0.448798423350262 -388.215788080547 236.283477350263 -1.64300861166463 0.101113842978936 IGFBP7-AS1 other 1 1 1 -0.758114953190949 -1.64300861166463 0.0101109570635908 10.6131911353163 17.6430580427393 0.601550542406339 0.547785288268496 -39.9792375765813 23.9647028387276 -1.66825509356927 0.0959814019479635 SMARCA5-AS1 other 1 1 1 0.601550542406339 -1.66825509356927 0.000223599908692889 0.0522434244455687 2.41071816473292 0.0216713115659278 0.982720017350412 -12.3210073921265 3.78661303964827 -3.25383324441068 0.00122677108096656 RORA-AS1 other 1 1 1 0.0216713115659278 -3.25383324441068 4.4494757202101e-23 52.7733030986336 25.2461338244839 2.09035187191528 0.0371661853201801 -212.23917965538 31.6590519076275 -6.70390194484144 6.314993618126e-11 BDNF-AS other 3.89596094061597e-19 5.98408795253619e-07 1 2.09035187191528 -6.70390194484144 6.56891996739794e-55 176.715387114879 26.035432036108 6.78749585832862 3.74023854329851e-11 -110.881366168106 34.2202038679292 -3.24023102246982 0.00128579227704707 ZNF585B other 6.32127168462703e-51 1 3.56818757030678e-07 6.78749585832862 -3.24023102246982 0.170344018356436 3.59072909209984 2.80628533275008 1.27953100498908 0.201390599700464 -2.85278797386414 5.14982972287703 -0.553957728192688 0.57989176648617 LINC02202 other 1 1 1 1.27953100498908 -0.553957728192688 1.84450300879734e-17 -112.594235104315 107.381979756204 -1.0485393858443 0.294968393052777 -770.029156846693 138.013677042266 -5.57936846078577 4.23486992640516e-08 CEBPA other 1.53407315241675e-13 0.000387405900867544 1 -1.0485393858443 -5.57936846078577 0.0155010160594962 0.446861213994733 9.45315958523634 0.0472710959722532 0.962318759416344 -33.1132369246735 14.7147068411401 -2.25034975430798 0.024923338801486 RAD51-AS1 other 1 1 1 0.0472710959722532 -2.25034975430798 0.956291683815269 13.5105564387892 46.5298151559333 0.290363423828611 0.771675960397455 17.9781058369272 92.4203845036273 0.194525330461285 0.845854962010248 ALDH1L1-AS2 other 1 1 1 0.290363423828611 0.194525330461285 0.479022141032775 -0.606221006623254 3.22941370896321 -0.187718595775045 0.851184581650273 6.91966857050914 6.80878029715708 1.01628607012013 0.310056795082717 NUDT16P1 other 1 1 1 -0.187718595775045 1.01628607012013 2.27255129148697e-07 29.0080918408147 10.3118426688866 2.81308518489517 0.00512760212095363 -8.90583720913912 12.3095145379335 -0.723492155738109 0.469763768497679 LINC01550 other 0.00143534339570317 1 1 2.81308518489517 -0.723492155738109 1.48555717189863e-18 42.9972972442692 19.1213401372225 2.24865500721723 0.025030789439922 -110.144148607418 23.1715075199586 -4.75343041502786 2.71719837963708e-06 SBF2-AS1 other 1.25202758447616e-14 0.023577130340111 1 2.24865500721723 -4.75343041502786 0.107302576881024 -13.341583002569 29.5391638231969 -0.451657436291135 0.651740887682145 -99.0277609152472 50.7658820638577 -1.95067547118912 0.0517374134686812 UBAP1L other 1 1 1 -0.451657436291135 -1.95067547118912 0.412677734365639 10.8042311476877 23.2954006690082 0.463792458485656 0.643026848297562 -26.7568208247605 37.0936672177313 -0.72133123607607 0.471090598028299 SOCS2-AS1 other 1 1 1 0.463792458485656 -0.72133123607607 5.31504541513841e-08 217.162163908067 41.2814605955621 5.26052520368945 2.25437262659739e-07 -59.8797677322985 74.0456061586452 -0.808687656685586 0.419134866058875 PGAM5 other 0.000348135474691566 1 0.00205012646662767 5.26052520368945 -0.808687656685586 0.00550198378671421 24.6515333280655 12.9390247261543 1.90520799285869 0.0574076351621434 -0.667805657921074 15.0172844302259 -0.0444691356166203 0.964550719871721 MIR210HG other 1 1 1 1.90520799285869 -0.0444691356166203 0.000144113326904122 8.91075783988607 4.07499399198335 2.18669226443426 0.0292957825665771 -12.2476167427367 7.07019437657203 -1.73228854687796 0.0839293989525859 UBL7-AS1 other 0.700246655427127 1 1 2.18669226443426 -1.73228854687796 1.17483919641001e-08 36.9705646001363 18.9708663016443 1.94880739826477 0.0519565196763876 -61.1719396410607 23.0073647816791 -2.65879818143155 0.00812925234193408 ZBED5-AS1 other 7.99948008835577e-05 1 1 1.94880739826477 -2.65879818143155 3.28410575942335e-08 55.8513249405511 20.5649163106854 2.71585471570974 0.0068732345018562 -56.5066115549766 27.226101821887 -2.07545729185333 0.0385298992022314 DNAJC3-AS1 other 0.000217834735022551 1 1 2.71585471570974 -2.07545729185333 2.92689403452492e-05 348.505397727272 80.1003826108197 4.35085809041063 1.68987291567508e-05 166.747745028409 122.394740697695 1.36237671715211 0.173780764729849 TWF2 other 0.155242459591202 1 0.14541356439384 4.35085809041063 1.36237671715211 8.85508184151823e-07 218.442767875851 58.103037722894 3.75957568548571 0.000193335298854684 -80.473848343383 74.389110046988 -1.08179608940814 0.279939735356263 LRP4-AS1 other 0.00538477526782724 1 1 3.75957568548571 -1.08179608940814 8.28205344357416e-09 5.32291482496469 4.62474596052763 1.15096372220138 0.250375093774087 -32.3458384900991 7.41223416688844 -4.36384466030401 1.59571901704335e-05 STX18-AS1 other 5.68066045694752e-05 0.13362551048721 1 1.15096372220138 -4.36384466030401 1.29396908965333e-13 57.6624906604566 27.6169654975271 2.08793723791341 0.037384635642055 316.177112474152 42.6056675541823 7.42101064540451 6.16014218645618e-13 PCED1B-AS1 other 1.01667151374062e-09 5.92667279758949e-09 1 2.08793723791341 7.42101064540451 3.75596290893133e-06 2.40827858081475 2.82011726606517 0.853963985751187 0.393591742078211 -13.0324385207435 3.964319788196 -3.28743371297853 0.00109247424332163 SEC24B-AS1 other 0.0217658050572571 1 1 0.853963985751187 -3.28743371297853 0.00247954376758005 20.3304424172342 10.8880837910674 1.86721950412553 0.062543308766728 -18.5527217439718 16.762176804778 -1.10682054962476 0.268983206250326 LINC00926 other 1 1 1 1.86721950412553 -1.10682054962476 0.220896670502465 22.1809464642645 18.4546486583474 1.2019164859165 0.230046798238077 -20.7552386268818 34.6319774093151 -0.599308505592268 0.549277747669928 NRAV other 1 1 1 1.2019164859165 -0.599308505592268 3.27554549732874e-06 15.105612148566 25.114865871861 0.601460992291842 0.547844148846428 -121.235095259074 36.5120324270572 -3.32041486601095 0.000974035375696531 FAM13A-AS1 other 0.0190702258854479 1 1 0.601460992291842 -3.32041486601095 6.49100151994965e-07 55.6885777860195 22.1339485446726 2.51598026776036 0.0122275727215531 -64.7815687001665 32.9026643012482 -1.96888519747347 0.0495977444210574 UBA6-AS1 other 0.00398677313355307 1 1 2.51598026776036 -1.96888519747347 0.728035035399275 2.11446561491826 5.03050188522418 0.420328957857855 0.674452234701031 -2.16538041040214 7.88770941311223 -0.274525885398681 0.783810541276292 DPH6-AS1 other 1 1 1 0.420328957857855 -0.274525885398681 2.19645671277559e-39 65.5320966945162 63.5427280252093 1.03130757414944 0.302970976621067 -615.094941072373 84.5498945495469 -7.27493445555893 1.63340748585403e-12 BCKDHA other 2.0475369476494e-35 1.56872454941421e-08 1 1.03130757414944 -7.27493445555893 1.21638582622742e-14 113.594066280905 18.3251822722295 6.1987959843133 1.31538180273929e-09 -108.890283309536 40.2571713794581 -2.70486672506501 0.00709956851780429 TRIM39-RPP21 other 9.71892275155711e-11 1 1.23882658181986e-05 6.1987959843133 -2.70486672506501 6.30975859115482e-89 357.026968867102 44.0842214656027 8.09874728412017 5.56182745993436e-15 -428.976466568782 58.4664797289395 -7.33713520221483 1.06733632617897e-12 CDK11B other 6.20627855025988e-85 1.02592367672322e-08 5.39330408789835e-11 8.09874728412017 -7.33713520221483 0.00176579095260747 -136.189523770291 138.014430678268 -0.986777419585698 0.324299048223994 -1038.75119469392 290.984686699444 -3.56977958694726 0.000396994567684788 PCDHAC1 other 1 1 1 -0.986777419585698 -3.56977958694726 3.266231725444e-08 -38.7380810409114 63.5397978579338 -0.609666419265677 0.542400387845467 -497.97532402422 97.0962244215245 -5.12867855563937 4.39794246480665e-07 ABHD14A other 0.000216779799617718 0.0039260432383329 1 -0.609666419265677 -5.12867855563937 0.000207826344241198 18.3959299104946 22.0563996549163 0.834040468902833 0.404713844904817 -88.6691740283957 33.6685033345783 -2.63359416803451 0.00874834204785099 SRP14-AS1 other 0.985928177080243 1 1 0.834040468902833 -2.63359416803451 0.0423989453794572 46.008022922636 29.9755541781603 1.53485145426124 0.125545631869606 -63.9615090735437 64.3389341157162 -0.994133800204186 0.320709130224032 GDNF-AS1 other 1 1 1 1.53485145426124 -0.994133800204186 1.03983630595008e-06 55.4587821347577 53.3493086535493 1.03954078383484 0.299126799131209 -294.286594743452 82.2876851339599 -3.57631393159704 0.000387299866998766 TMEM110-MUSTN1 other 0.00629516899622176 1 1 1.03954078383484 -3.57631393159704 0.000745639991119658 -0.514902909756205 12.5437777691283 -0.0410484719382898 0.967276217490711 -93.2085012314021 27.563430835704 -3.38160012761058 0.000786228914224183 OXCT1-AS1 other 1 1 1 -0.0410484719382898 -3.38160012761058 0.0196533050039266 -4.65553102979873 3.86360763022053 -1.20496993364023 0.228899934103849 -18.6432634349265 6.66023332672795 -2.7991907370737 0.00536150482239987 USP46-AS1 other 1 1 1 -1.20496993364023 -2.7991907370737 0.0889089094436701 -10.3889026612565 65.6056674113819 -0.158353737888415 0.874251048043363 108.96408654213 49.4428056428135 2.20384108720109 0.0280550972958486 TNFSF12-TNFSF13 other 1 1 1 -0.158353737888415 2.20384108720109 3.19279354991521e-05 34.1177843472848 7.88909813780195 4.32467485526687 1.89423194120233e-05 21.19866189513 10.6281627360869 1.99457445482576 0.0467100448515096 HHIP-AS1 other 0.168483715629026 1 0.162600869832808 4.32467485526687 1.99457445482576 0.0763629945851074 -57.5902416960486 33.0642001274072 -1.74177029760692 0.0822522642703216 -117.34883559102 52.9921052261109 -2.21445883476995 0.0273125152438544 FMN1 other 1 1 1 -1.74177029760692 -2.21445883476995 6.4182666049847e-32 2.71635024237275 13.7848908892915 0.197052719835664 0.843877896810327 -119.273256852403 17.6212945938236 -6.76870000767195 4.196652084703e-11 ZNF436-AS1 other 5.84960818378306e-28 3.98430148921703e-07 1 0.197052719835664 -6.76870000767195 3.03465677290568e-42 290.813392584292 33.8406340802844 8.59361535290265 1.50937449020627e-16 12.4114688012626 45.0531580134407 0.27548499036538 0.783073868595608 HAUS5 essential 2.84984617543572e-38 1 1.46831950407266e-12 8.59361535290265 0.27548499036538 0.00207923487516408 -154.030640898579 145.367326036365 -1.05959602545105 0.289916411733494 -1082.05054509415 306.493853107888 -3.53041515880994 0.000459183027266815 PCDHA11 other 1 1 1 -1.05959602545105 -3.53041515880994 0.757450398591254 3.18406466331641 4.36717705827893 0.729089895102908 0.466337240280298 2.32404830410365 6.47668839927408 0.358832810972369 0.71989346391825 ATP5L2 other 1 1 1 0.729089895102908 0.358832810972369 0.0192520955812606 7.19819151735195 71.2874979971146 0.100974107937458 0.91961732397633 -214.740796115115 105.146726492332 -2.04229654387552 0.0417218416726741 TMEM150C other 1 1 1 0.100974107937458 -2.04229654387552 0.742700112778499 30.0582799855057 110.673195978938 0.271594939674697 0.786061454685292 -108.012889755492 212.2450683805 -0.508906475800195 0.611074035259669 LINC01411 other 1 1 1 0.271594939674697 -0.508906475800195 0.000272060036504116 1.3728307164201 5.24753780000331 0.261614259628436 0.793742108009804 -27.4927069307271 8.51245451092904 -3.2297038293044 0.00133269979592944 UGDH-AS1 other 1 1 1 0.261614259628436 -3.2297038293044 0.000402847021029845 64.0577603875538 20.155158889714 3.17823147602399 0.00158674187053342 33.9366144072685 15.0858305843133 2.24956883995216 0.0249721864519384 ZNF286B other 1 1 1 3.17823147602399 2.24956883995216 7.72867245978194e-44 30.3102247301328 8.85447947614458 3.4231515033485 0.000677477342218565 -45.5903097510516 10.9956234833944 -4.14622325145112 4.06319045711378e-05 ZNF324B other 7.28504666059045e-40 0.332531507010192 1 3.4231515033485 -4.14622325145112 2.08318086446555e-07 12.7091587739434 9.17026903727438 1.38590904173962 0.166481483418898 -42.0502131517525 12.7846612969858 -3.28911436720395 0.00108631913310509 MIR302B other 0.00131865348720669 1 1 1.38590904173962 -3.28911436720395 0.00259038274815354 39.7536191082996 11.8485155618058 3.35515608693185 0.000862582947879443 55.8125620471487 23.0175698314095 2.42478082855591 0.0157230501609597 LINC01234 other 1 1 1 3.35515608693185 2.42478082855591 0.696260858294647 -1.93304575089899 8.30419425479607 -0.232779447540327 0.816041657518204 -13.4456075764387 15.9968677696488 -0.840515016442739 0.401079324513595 MIR143 other 1 1 1 -0.232779447540327 -0.840515016442739 4.27171177956451e-14 31.2987563140213 24.9310834578282 1.25541099595468 0.210000468856371 -247.319695719548 41.3597844644919 -5.97971432689346 4.65094710315386e-09 NOP14-AS1 other 3.38661309883875e-10 4.31607891172678e-05 1 1.25541099595468 -5.97971432689346 0.0434587312337856 3.9052096663513 6.26530687701214 0.623307005229033 0.533419519795069 -18.732895639756 10.8247105962552 -1.73056780346965 0.0842598966922687 SRD5A3-AS1 other 1 1 1 0.623307005229033 -1.73056780346965 0.199630150300351 -15.6455378047102 10.5995678848731 -1.47605430472673 0.140647847402205 -25.3964071753202 14.1947750754213 -1.78913769611573 0.0742834963317814 HS3ST5 other 1 1 1 -1.47605430472673 -1.78913769611573 9.58295876869349e-07 1.81517823794172 2.92834894418233 0.619864050542162 0.535671105444796 -16.5633597741244 4.42837487729987 -3.74027950050689 0.000208354573031752 BRD9P2 other 0.00581685597259695 1 1 0.619864050542162 -3.74027950050689 1.25882742924312e-21 186.82421804838 77.5118276075678 2.41026723036704 0.0163577376939044 -773.740781076277 119.20744197538 -6.4907087028684 2.34783009813012e-10 PDCD6 other 1.09165514663964e-17 2.21447334855633e-06 1 2.41026723036704 -6.4907087028684 0.332272789344575 76.0818155368073 134.535175586804 0.565516157428423 0.572012307010463 -157.887463056826 211.720781650384 -0.7457343668679 0.456227909012376 TMEM158 other 1 1 1 0.565516157428423 -0.7457343668679 2.30787510619025e-06 81.1368172047538 64.0451820720458 1.26686839789886 0.20587557769863 -436.311193416503 121.88961329633 -3.57956007585136 0.000382656678049166 C15orf38-AP3S2 other 0.0135956922505668 1 1 1.26686839789886 -3.57956007585136 0.00114842001691175 -7.9483786472994 16.0039582809994 -0.496650797742711 0.619684491756004 -66.3295755483176 21.7640685361323 -3.04766433896302 0.00244583550099965 SLC7A11-AS1 other 1 1 1 -0.496650797742711 -3.04766433896302 0.630898414974952 8.71573304580445 10.3100658660658 0.845361529114099 0.398372685383764 2.82535169719965 16.7144343212728 0.169036632822433 0.865846220226371 LINC01018 other 1 1 1 0.845361529114099 0.169036632822433 0.00407572331909137 -133.645874628345 156.247123382821 -0.855349344902174 0.392828641890177 -1092.3228444004 329.432921333674 -3.31576710663357 0.000990508204192989 PCDHA10 other 1 1 1 -0.855349344902174 -3.31576710663357 0.112131983560908 1.08342195509556 3.42848302843838 0.31600621794212 0.752149704552312 -6.45882971477745 4.91107745928835 -1.31515533369603 0.189152128721469 LINC02232 other 1 1 1 0.31600621794212 -1.31515533369603 1.682508023361e-05 81.7630122412702 17.6698335651487 4.62726555628326 4.89337161627158e-06 9.78383182730271 32.8094500550582 0.298201640408 0.765691325319789 FZD10-AS1 other 0.0914779612301376 1 0.0429882696489459 4.62726555628326 0.298201640408 0.0911446545809642 33.951414944356 17.4457809977429 1.94611034890033 0.0522821009994996 -0.988734953441018 34.6518846544756 -0.0285333673276358 0.977249781354691 ALDH1L1-AS1 other 1 1 1 1.94611034890033 -0.0285333673276358 0.881465566169105 -33.447016185493 70.0907884085427 -0.477195605084911 0.633461398443939 -9.53713603228524 184.612295910128 -0.0516603511443682 0.958822935512258 KIAA1456 other 1 1 1 -0.477195605084911 -0.0516603511443682 0.187378001784761 -1.3371691446448 17.9313673874609 -0.0745715101225275 0.940590240520429 -42.2741323527841 27.885923244397 -1.51596674717514 0.130260810654756 ZNF718 other 1 1 1 -0.0745715101225275 -1.51596674717514 0.000717426847154687 61.8671501857422 37.8482405260208 1.63461099712702 0.102852382874541 -122.178579298059 61.6181661086706 -1.98283374877765 0.0480131320203534 SMIM20 other 1 1 1 1.63461099712702 -1.98283374877765 0.220941591627211 -20.4964445081783 40.8507767648251 -0.501739406968314 0.616104100945196 -67.8489181688586 48.5519165052764 -1.39745087429216 0.162988708400103 TUNAR other 1 1 1 -0.501739406968314 -1.39745087429216 0.854337857516798 7.18177084640261 51.6990025971898 0.138915075448535 0.889581104901153 42.7756486662814 82.1843041614218 0.520484405176247 0.602988987204392 CHCHD10 other 1 1 1 0.138915075448535 0.520484405176247 0.0305338472946721 13.9662139333739 10.6555803418713 1.31069481767158 0.190647710962006 -9.36940030421255 14.3020794444555 -0.655107555555131 0.512742405790892 FAM218A other 1 1 1 1.31069481767158 -0.655107555555131 7.81556035480314e-21 191.601419333608 19.021220602532 10.0730349191209 1.33909384460513e-21 107.792812062473 60.4670409109504 1.78267053321195 0.0753340451779015 GLI4 other 6.73466835773387e-17 1 1.31124069263734e-17 10.0730349191209 1.78267053321195 0.000572925514974192 27.5745681720999 11.7168373565488 2.35341392331335 0.0190440518050809 -2.3573301175883 14.0837329381016 -0.16737963776712 0.867148772509812 CCDC169-SOHLH2 other 1 1 1 2.35341392331335 -0.16737963776712 0.830418183933426 -307.776190757254 778.756965706194 -0.395214687393718 0.692879980932279 408.317913002406 1774.42902504976 0.23011228245151 0.818113695509693 SELENOP other 1 1 1 -0.395214687393718 0.23011228245151 5.87158994726667e-05 110.002331728416 34.6950717734793 3.17054630832327 0.0016288390637976 234.187081156609 53.018117601991 4.41711421960811 1.2633090065779e-05 LINC02381 other 0.299509803210073 0.106433783804188 1 3.17054630832327 4.41711421960811 0.0979042794800653 18.1483649487259 17.8629874892273 1.0159759088266 0.310204304832223 -26.766922670657 29.6359202550171 -0.90319188472393 0.366922788629966 SNHG18 other 1 1 1 1.0159759088266 -0.90319188472393 0.291177793662273 4.91025870672221 5.33023030893987 0.921209482916098 0.357451674512869 -2.17707720258965 7.49131837423722 -0.29061335986956 0.771485539819057 EPHA5-AS1 other 1 1 1 0.921209482916098 -0.29061335986956 0.000113163220390873 -4.8990608493669 21.0246005487015 -0.233015644602554 0.815858357909205 -87.9300904160473 28.0863612893578 -3.13070424146986 0.00186087344126397 SMAD1-AS1 other 0.557555186865832 1 1 -0.233015644602554 -3.13070424146986 8.26612413428294e-10 -2.90134848663301 18.9736596862383 -0.152914542297677 0.87853608655279 -92.9798904722651 23.0016934027584 -4.04230631389578 6.25257998529548e-05 GLUD1P3 other 5.90449246911831e-06 0.504833308012757 1 -0.152914542297677 -4.04230631389578 1.21989696318436e-05 19.8857382877544 9.79296843111189 2.03061394791984 0.0429005433540921 -52.2748893655966 19.1999148891665 -2.7226625569623 0.00673556079032575 SNHG21 other 0.0672285216410899 1 1 2.03061394791984 -2.7226625569623 2.46702999047065e-09 196.888298894262 56.5938144206206 3.4789720556903 0.000553722501587727 -139.861283878718 82.8544207388896 -1.68803646964695 0.0921160696544652 THAP9-AS1 other 1.72988142931802e-05 1 1 3.4789720556903 -1.68803646964695 5.61294424504434e-40 31.531044043254 6.91100199051916 4.56244175396127 6.58202047956546e-06 -32.8361241137659 9.04268715762392 -3.63123522260544 0.000315583520087727 ZNF345 other 5.2413673360224e-36 1 0.0575531870733204 4.56244175396127 -3.63123522260544 0.0036871879559108 82.498667250611 170.187722709421 0.484750991065728 0.62809699230629 -542.776218918241 249.988822417113 -2.17120195083204 0.0304558396148238 SHANK3 other 1 1 1 0.484750991065728 -2.17120195083204 3.15550743887825e-31 45.6808379295226 15.3851340570791 2.96915436420938 0.00315054545842434 -59.1722405556964 19.2969555086611 -3.06640291154416 0.00230096901922361 ZNF550 other 2.86867181268422e-27 1 1 2.96915436420938 -3.06640291154416 0.00160046326444948 1.00358472356274 11.9171250561644 0.0842136604955415 0.932925209959941 -78.4741978688621 24.3485065625338 -3.22295733692407 0.00136395601724355 RPL32P3 other 1 1 1 0.0842136604955415 -3.22295733692407 0.00846535635409002 16.9944923957814 13.8202975552681 1.22967630239649 0.219489172349616 -33.4999680718594 21.4926027956146 -1.5586743211341 0.119807434492133 ABCA11P other 1 1 1 1.22967630239649 -1.5586743211341 0.00174918626808124 -132.73616100925 136.721903535586 -0.970847812799073 0.332163576371981 -1029.33802031715 288.265762062543 -3.5707952722246 0.000395596221400415 PCDHA12 other 1 1 1 -0.970847812799073 -3.5707952722246 0.000113927885107226 7.27807858910892 7.07857235303896 1.02818453017356 0.304430491250053 -32.2213799504952 11.3450633387874 -2.84012340771462 0.00471972512197397 FAM86EP other 0.561208762038193 1 1 1.02818453017356 -2.84012340771462 0.000225691963947651 -2056.30328887873 2847.57736288184 -0.722123765865901 0.470604616258925 -24343.0738739109 6003.60181615943 -4.05474490469847 5.94268465168768e-05 PCDHGA12 other 1 0.480882042014567 1 -0.722123765865901 -4.05474490469847 1.16930409933584e-31 67.162792163785 12.9466272678225 5.18766708691084 3.26230497661639e-07 -32.9947805849317 16.6247308341685 -1.98468058906061 0.0478035099051027 TMEM200B other 1.06418366080555e-27 1 0.00295825815279575 5.18766708691084 -1.98468058906061 0.000301275842086355 -2000.0152011753 2868.11256819036 -0.697328000078188 0.485968360200671 -24070.3567524249 6046.89658226218 -3.98061326582503 8.0478058170269e-05 PCDHGB6 other 1 0.645112114292877 1 -0.697328000078188 -3.98061326582503 7.45944605596157e-21 3.42912506040947 1.92072812867194 1.78532558003433 0.0749035307736995 -10.609515921101 2.22878491419165 -4.76022421613928 2.63527049687272e-06 SERPINE3 other 6.42855061102768e-17 0.0228767831833521 1 1.78532558003433 -4.76022421613928 0.0720295659955025 -65.6308070561998 44.0914107603333 -1.48851683183711 0.137339221733992 -18.4312020529081 56.4098002261918 -0.32673758777735 0.744023521825856 TRNP1 other 1 1 1 -1.48851683183711 -0.32673758777735 0.000186843263308873 -1899.20535714275 2813.00931042006 -0.675150754072387 0.499937052870279 -24253.5551948053 5930.72133001502 -4.08947813347079 5.14735472628206e-05 PCDHGA5 other 0.893858171669648 0.418840254077571 1 -0.675150754072387 -4.08947813347079 0.000196417399065903 -1849.46694168163 2808.03084454316 -0.658634838458307 0.510477144648576 -24120.0653254973 5920.22513518995 -4.07418041961397 5.48429968332664e-05 PCDHGA7 other 0.935928906549026 0.444667018324124 1 -0.658634838458307 -4.07418041961397 0.00179469649542306 209.47260273972 83.4877530151404 2.50902192446996 0.0124675206503303 357.864511986297 101.224837311519 3.53534292068035 0.000450733434790532 EIF5AL1 other 1 1 1 2.50902192446996 3.53534292068035 3.8871760173536e-09 62.8750093823951 43.467971686515 1.44646752408511 0.148764612641636 -135.216369217317 50.4396005344084 -2.68075813021312 0.00762405084752313 ALG11 other 2.70158733206075e-05 1 1 1.44646752408511 -2.68075813021312 6.00860792430034e-21 110.808039165163 10.89693469497 10.1687348109291 6.06448011504961e-22 84.9734604483372 34.6405422540019 2.45300607090007 0.0145565449582033 MINCR other 5.1836260562939e-17 1 5.9407647207026e-18 10.1687348109291 2.45300607090007 1.65348036813603e-11 42.7162598493227 277.982251181924 0.153665421686823 0.877944322811414 -2716.98115839966 463.057177945926 -5.86748524329523 8.73696892826101e-09 ATXN7L3B other 1.24077166824928e-07 8.07295928971317e-05 1 0.153665421686823 -5.86748524329523 0.000250651586058581 -1780.3090528932 2808.71570617079 -0.633851638662408 0.526509271636021 -23752.4629500247 5921.66904205797 -4.0111094999274 7.10797328917686e-05 PCDHGA6 other 1 0.571836451114278 1 -0.633851638662408 -4.0111094999274 0.000199475155533575 -1828.45349231454 2801.40479340876 -0.652691641213934 0.51429828867388 -24034.0362691107 5906.25530485524 -4.06925116314453 5.59726569833189e-05 PCDHGA8 other 0.949501740339817 0.45349046687885 1 -0.652691641213934 -4.06925116314453 6.42479744813351e-16 188.924643238552 97.347972571659 1.94071471904032 0.0529370938586914 -418.621778217307 112.961167932119 -3.7058910232662 0.000237762692655165 UTP14C other 5.24070727844251e-12 1 1 1.94071471904032 -3.7058910232662 0.000195765682736596 -2097.06978978288 2866.87001089242 -0.73148408606433 0.464875576981869 -24722.6297673846 6044.27687494612 -4.09025434785446 5.1307938107975e-05 PCDHGA10 other 0.933215009605352 0.417544000322701 1 -0.73148408606433 -4.09025434785446 0.000206255977121565 -1772.15387658217 2835.38074024563 -0.625014429782945 0.532287801881662 -24241.7228135789 5977.8874433862 -4.05523239491559 5.9307548115804e-05 PCDHGA11 other 0.978684611441827 0.479975986901202 1 -0.625014429782945 -4.05523239491559 0.000186644996881033 -1882.47225361654 2852.09352219766 -0.660031741233373 0.50958118087181 -24572.3258466218 6013.12332121981 -4.08644967581293 5.212455710604e-05 PCDHGB2 other 0.893096310075743 0.424033272057635 1 -0.660031741233373 -4.08644967581293 0.000171388226446463 -1933.29639466537 2804.07899181128 -0.689458606662348 0.490900640520719 -24313.9543194148 5911.89336849327 -4.11271868484522 4.67288371162864e-05 PCDHGB4 other 0.824205980981042 0.381167124357548 1 -0.689458606662348 -4.11271868484522 4.24045065643707e-49 360.615019638626 47.1417677562915 7.64958627565464 1.30318989753158e-13 -111.728265372586 62.8069422026147 -1.77891585634198 0.0759501914234019 ZNF260 other 4.04114947558453e-45 1 1.25875112202576e-09 7.64958627565464 -1.77891585634198 0.000206126310309433 -702.000508589404 2896.73192883914 -0.242342241475803 0.80862867706787 -24137.4059879994 6107.23532768416 -3.95226394479746 9.02620352388126e-05 PCDHGB7 other 0.97827546872857 0.721193661558113 1 -0.242342241475803 -3.95226394479746 0.000162805372060527 -1793.04379520784 2819.80414032911 -0.635875296997956 0.525190567530387 -24451.6469464081 5945.04699986835 -4.11294426216471 4.6684891204614e-05 PCDHGB1 other 0.785861530936163 0.380902027338445 1 -0.635875296997956 -4.11294426216471 0.000253858410560695 -1973.36431962014 2812.83883111219 -0.70155612820514 0.48332945709316 -23855.2469792866 5930.3619052297 -4.02256175263938 6.78272779141218e-05 PCDHGA3 other 1 0.546552205431994 1 -0.70155612820514 -4.02256175263938 2.06355176868097e-06 9.71435221553061 1.88344797170602 5.15774917144719 3.79378708654016e-07 5.97329975020466 5.91098113216149 1.01054285517917 0.312793195071481 RHPN1-AS1 other 0.0122038451599793 1 0.00343641234298807 5.15774917144719 1.01054285517917 8.66888617421254e-19 226.606981711095 25.4460189697543 8.9054001720444 1.47823539139641e-17 3.35596424345329 69.0347899532604 0.0486126523413112 0.9612504011962 LRRC24 other 7.32694259444444e-15 1 1.4405403889158e-13 8.9054001720444 0.0486126523413112 8.72320038917461e-05 213.780967228117 103.279911029444 2.06991819703612 0.0390483367300626 -228.13836264841 151.689780258554 -1.50397978202322 0.133310574613219 CHKB-CPT1B other 0.435200467415921 1 1 2.06991819703612 -1.50397978202322 4.74881707106723e-08 -10.6640216971479 31.8581631011027 -0.334734355628269 0.737986086584648 -120.970712210524 39.8422091373833 -3.03624509859367 0.00253871639937353 SIGLEC14 other 0.000312044769739828 1 1 -0.334734355628269 -3.03624509859367 0.000769761884041177 -40.1670677415481 23.1220528587026 -1.73717567324175 0.0830591396794275 -103.138633355575 28.2503492994284 -3.65087993293103 0.000292910180961023 SPON1-AS1 other 1 1 1 -1.73717567324175 -3.65087993293103 0.00247175131862857 -2.05281218114743 12.3064772911186 -0.166807456966496 0.867598529980125 -41.9290730711876 15.4275623649699 -2.7178028569434 0.0068323744392818 NAV2-AS2 other 1 1 1 -0.166807456966496 -2.7178028569434 4.33046198122711e-12 316.407344137615 63.1380935040626 5.01135410617452 7.85799248772065e-07 -83.5143504145263 93.64308733269 -0.891836790021896 0.372970090881294 CHMP4A other 3.29158415193073e-08 1 0.00707062164045104 5.01135410617452 -0.891836790021896 1.21511027132939e-05 21.08898995787 4.38009446263241 4.8147340514651 2.03469765586526e-06 18.2746524347891 5.98416381041867 3.05383559236332 0.00239743974464792 PABPC4L other 0.066983831919829 1 0.0180925315559539 4.8147340514651 3.05383559236332 0.349592480317707 -27.5950545067798 25.3182350643987 -1.08992804737731 0.27634962791028 -61.6209154900011 43.6384457253368 -1.41207860329965 0.158643414449511 MAGEL2 other 1 1 1 -1.08992804737731 -1.41207860329965 0.430686403656647 41.1517131111626 62.0952961322727 0.662718686831012 0.50785932065985 -22.8431139387002 75.3692313692883 -0.303082750396847 0.761970697034135 CSNK2A3 other 1 1 1 0.662718686831012 -0.303082750396847 2.45056660136949e-43 68.0662938171573 20.8813256029276 3.25967302610397 0.00120258611816094 -147.59019376431 26.8262668476796 -5.50170452722073 6.4169686389051e-08 FPGT other 2.30794362516978e-39 0.000584521673317866 1 3.25967302610397 -5.50170452722073 0.85818507740593 -25.0055364566676 65.7468248477089 -0.380330708206649 0.703884313319368 11.535470632129 106.23490288905 0.108584564191454 0.913581729836764 IGLL5 other 1 1 1 -0.380330708206649 0.108584564191454 4.13971347604931e-06 88.8033280150767 17.711960063526 5.01374933641299 7.76600905638244e-07 95.5675150892136 40.8786851527075 2.33783241149291 0.0198453061181928 CKLF-CMTM1 other 0.0238944261837566 1 0.00698863154983856 5.01374933641299 2.33783241149291 0.11635069760426 -6.8439924781323 9.64872152686415 -0.709315991665541 0.478505804145723 9.51961668866884 11.6665386784226 0.815976096344279 0.414957332391196 GVINP1 other 1 1 1 -0.709315991665541 0.815976096344279 0.0276862097263914 7.75480769230774 6.17246891542269 1.25635427226395 0.209658748197719 -5.41736104804287 7.4756139954224 -0.724671050613385 0.469041673122805 TMEM9B-AS1 other 1 1 1 1.25635427226395 -0.724671050613385 6.49489548577356e-11 475.623882167285 189.89866328467 2.50461943196669 0.0126206527205733 -2126.51251221161 417.173642205246 -5.09742777844382 5.13198367707781e-07 ATP6V1G2-DDX39B other 4.80297521172955e-07 0.00457157105954092 1 2.50461943196669 -5.09742777844382 6.51549478589992e-05 226.040492539408 132.50125315484 1.70594984694416 0.0887295785921534 -906.340957417633 280.107701474027 -3.23568738970097 0.00130593998403763 ANKHD1-EIF4EBP3 other 0.330270430697267 1 1 1.70594984694416 -3.23568738970097 3.84728766108056e-11 679.075640609487 125.323837252231 5.41856725343284 9.93600796360154e-08 -586.420254879547 279.283077831564 -2.09973428906859 0.0363237374084109 BRK1 other 2.86276674861005e-07 1 0.000909045368589905 5.41856725343284 -2.09973428906859 0.872897250750993 -15.8624716463435 61.6141905939436 -0.257448349048064 0.796953864734384 -39.1002204034949 76.7067250152483 -0.509736537386028 0.610493375484042 SAA2-SAA4 other 1 1 1 -0.257448349048064 -0.509736537386028 5.58105784894995e-15 11.7640730784096 19.5778250476344 0.600887639448543 0.548225643183524 -164.290744720067 28.4622735648922 -5.77222843233147 1.48276896835655e-08 PIGY other 4.48437998163129e-11 0.00013665198812374 1 0.600887639448543 -5.77222843233147 2.63700225314688e-13 98.945646920338 62.5338379196032 1.58227369712295 0.114313862762676 -471.592169679679 98.0981553228711 -4.80735002740393 2.11035706781595e-06 CHMP1B other 2.05791655835583e-09 0.0184023136313551 1 1.58227369712295 -4.80735002740393 0.281844806185466 6.59337748344355 5.66794923115824 1.16327391346379 0.245353174404192 -2.4196247240618 9.61863000434895 -0.251556065985259 0.801502473220729 EID3 other 1 1 1 1.16327391346379 -0.251556065985259 9.25103474996899e-05 189.585814346618 44.9215858309273 4.22037225177598 2.96666894084805e-05 56.033052882673 101.446508975783 0.552340868585721 0.580996570661884 MSH5-SAPCD1 other 0.460516509853456 1 0.252671193692028 4.22037225177598 0.552340868585721 0.00134541441325168 0.732832747971199 5.8920650871081 0.124376213965227 0.901074464762846 -14.1715032143415 6.79653358847488 -2.08510750809393 0.0376380381747699 TOLLIP-AS1 other 1 1 1 0.124376213965227 -2.08510750809393 0.00718655444312154 20.3612894153463 18.539979651743 1.09823688039658 0.272707174383118 -61.2458806207189 31.093357900445 -1.96974160258974 0.0495005590048497 HTD2 other 1 1 1 1.09823688039658 -1.96974160258974 0.8238608994042 6.82211142052643 11.8004871006843 0.578121170958343 0.563479421042646 -0.736305791937899 28.163347900209 -0.0261441144904664 0.979154297840726 PDXDC2P other 1 1 1 0.578121170958343 -0.0261441144904664 1.49781538621421e-18 176.817118101728 289.19340333108 0.611414769718313 0.541243677180673 -3017.78192532168 437.254955089576 -6.90165289196884 1.82064561249843e-11 EID1 other 1.26220902596272e-14 1.73380081678225e-07 1 0.611414769718313 -6.90165289196884 0.271031532661926 46.8007578328241 29.9208706837657 1.56415093422455 0.118507621101487 22.2460128944691 59.3289263828386 0.374960651587046 0.707872053572598 TBX5-AS1 other 1 1 1 1.56415093422455 0.374960651587046 0.00151915923137243 -129.608910431119 147.200116705823 -0.880494617338795 0.379077610981028 -1116.86800049554 310.358126390881 -3.59864268251479 0.000356660810727721 PCDHA3 other 1 1 1 -0.880494617338795 -3.59864268251479 1.3841085334777e-14 214.956921522899 74.5049293493166 2.88513690839263 0.00410559381848784 -440.350470644743 110.501778222445 -3.9850080037472 7.90265889052592e-05 NEDD8-MDP1 other 1.10521066398194e-10 0.633714216431274 1 2.88513690839263 -3.9850080037472 4.78782814318374e-12 89.3281889158261 78.8451828823924 1.13295683579136 0.257855012226674 -605.65499471318 121.373318557817 -4.99001759126058 8.73942057895313e-07 POLR2M other 3.63539790911941e-08 0.00772389990767878 1 1.13295683579136 -4.99001759126058 2.69411853731099e-09 7.27612257494613 1.47212631666205 4.94259391506857 1.10667319789925e-06 -7.84609262483017 3.98209524803699 -1.97034278090108 0.0494402492006232 ZNF252P-AS1 other 1.88696062353262e-05 1 0.00991025848718782 4.94259391506857 -1.97034278090108 0.00144516023446594 73.5558883363475 20.7401950805049 3.54653792072996 0.000432524819653576 90.926701463095 43.7269499595986 2.07942016415749 0.0381612640487586 PCDHB17P other 1 1 1 3.54653792072996 2.07942016415749 0.00747973461811443 2.21381949133471 4.17539305462504 0.530206249417042 0.596237620188661 -15.5504368465205 6.98427684232508 -2.22649204743489 0.0264891168627291 FAM222A-AS1 other 1 1 1 0.530206249417042 -2.22649204743489 0.406809708451341 -5.12733160500531 4.73511603963896 -1.08283124681275 0.27948181073655 -9.73151016562623 7.70759739373776 -1.26258672690051 0.207412610240648 LINC02389 other 1 1 1 -1.08283124681275 -1.26258672690051 0.0931711724162351 -113.184839137615 98.1425069356768 -1.15327030734804 0.249460063602721 -375.276172183378 171.760898139004 -2.18487546495985 0.0294539796525622 AGAP2-AS1 other 1 1 1 -1.15327030734804 -2.18487546495985 0.325614940698579 47.87222725508 38.4185285800263 1.24607133652611 0.213405798255368 -1.43153876019017 66.7891813816504 -0.021433692262374 0.982909480164575 RMST other 1 1 1 1.24607133652611 -0.021433692262374 1.39511041371208e-10 8.63240008128543 1.78521324842368 4.83550079460128 1.84575952552995e-06 -4.43643026175198 2.94559538891454 -1.50612344059474 0.132761282180368 TMEM5-AS1 other 1.02205788908547e-06 1 0.0164401800938953 4.83550079460128 -1.50612344059474 1.74895670558441e-09 286.334908973045 47.538901680042 6.02317047415622 3.63203943399987e-09 41.6692237048316 89.2114609996753 0.467083749530605 0.640672756571216 PXN-AS1 other 1.23283958176645e-05 1 3.40431056148807e-05 6.02317047415622 0.467083749530605 0.556615118253204 -4.23915204158742 7.73388693991844 -0.548126973476564 0.583884599176886 -11.2991045747104 10.5871041737056 -1.06725166668079 0.286447439861127 LINC00346 other 1 1 1 -0.548126973476564 -1.06725166668079 0.542698865458789 4.62019546706553 6.4669652114329 0.71443023365852 0.475342623619289 15.3277603780705 14.9039793470164 1.02843408603749 0.304314570538263 MT1JP other 1 1 1 0.71443023365852 1.02843408603749 0.172881772249038 -4.72348930166929 6.19121335555946 -0.762934344271594 0.445914190225209 -24.2134023042559 12.8999295027827 -1.87701818828022 0.0611816012792554 PAPPA-AS1 other 1 1 1 -0.762934344271594 -1.87701818828022 1.68439672411855e-06 37.5706748887704 204.990039297303 0.183280490201188 0.85466314108069 -978.264708220043 279.739199140065 -3.49705980151258 0.000518684441405421 CTSO other 0.0100305824921259 1 1 0.183280490201188 -3.49705980151258 5.37239026640018e-14 124.97557246072 40.3362607220447 3.09834303486684 0.00207250356611969 -105.951042980747 46.8505514586692 -2.26146842848189 0.0242244211422891 APOPT1 other 4.24956070072254e-10 1 1 3.09834303486684 -2.26146842848189 1.75699369303422e-51 55.583818863919 6.74967343816764 8.23503823897717 2.08744268233671e-15 2.20245404763917 8.46460358678729 0.260195769956323 0.794835038207448 TRAPPC2B other 1.68161866360305e-47 1 2.02523689040308e-11 8.23503823897717 0.260195769956323 0.0361588015226998 14.706043049771 13.6325619638711 1.07874389925715 0.281298333184205 -23.2713496350667 20.7919662479294 -1.11924718218433 0.263650924562708 DNAAF4 other 1 1 1 1.07874389925715 -1.11924718218433 5.46485711773357e-06 40.0170936581263 16.3826239081771 2.44265472261451 0.0149784873597481 -88.9711699099365 32.4268506817898 -2.743749949171 0.00632650815402309 URB1-AS1 other 0.0312097989993764 1 1 2.44265472261451 -2.743749949171 1.89952227176242e-62 176.335314183166 25.4444473579977 6.93020806080666 1.53535173114995e-11 -81.0642376363809 31.7344177891683 -2.55445800754693 0.0109773332681587 ZNF432 other 1.84348636474543e-58 1 1.46841039567181e-07 6.93020806080666 -2.55445800754693 0.236179176107065 -14.1193261241365 14.224194853318 -0.992627440058092 0.321442105072315 -42.4702479227547 26.4115679920059 -1.60801690893965 0.108555331573143 LINC00507 other 1 1 1 -0.992627440058092 -1.60801690893965 0.000441050248803295 68.1900970151935 21.3731983992273 3.19044888563139 0.00152310632800199 -45.4239719867128 38.3382032085116 -1.184822662128 0.236732995411104 ZNF10 other 1 1 1 3.19044888563139 -1.184822662128 0.687853718846643 -40.8313474220605 91.736629200986 -0.445093173552333 0.656472805835702 -152.112447541966 176.717774408267 -0.860764844121135 0.389839581018372 SMIM3 other 1 1 1 -0.445093173552333 -0.860764844121135 1.3667338944636e-29 41.4716367729614 22.7939439609558 1.81941470260693 0.0695338829757267 -122.745892568855 28.4162679080773 -4.31956416535489 1.93771104934128e-05 ZNF225 other 1.23498074703731e-25 0.161585724404569 1 1.81941470260693 -4.31956416535489 0.00276917621107092 34.0973502549827 13.9667450420315 2.44132402734997 0.0150302655250464 -42.1946761388903 29.525704532209 -1.42908278760498 0.153696492166682 DND1 other 1 1 1 2.44132402734997 -1.42908278760498 2.95879476859264e-10 1030.48335760742 191.036474924351 5.39417071015095 1.14795169433983e-07 184.152183830122 287.009760979969 0.641623417967914 0.521465242545118 SALL3 other 2.14660560461396e-06 1 0.00104934264379604 5.39417071015095 0.641623417967914 8.70420571968193e-07 14.006375048118 3.52888472302717 3.96906562481955 8.43060182150603e-05 30.0390436488936 6.37952349245403 4.70866573097897 3.3514446350967e-06 LINC02361 other 0.00529563875985449 0.0289665359811408 0.703618028022893 3.96906562481955 4.70866573097897 4.29976929329128e-18 -3.19276050357214 2.39937112512119 -1.33066555237922 0.183996175565362 -20.8134992793565 3.27705187700477 -6.35128770020574 5.38456448685167e-10 CYP2B7P other 3.60062680620212e-14 5.06095216119189e-06 1 -1.33066555237922 -6.35128770020574 0.507474256018198 -663.027522804148 571.893993914184 -1.15935388351646 0.246950888067366 60.9226772703805 424.289294654701 0.143587589971982 0.885892939486297 MTRNR2L1 other 1 1 1 -1.15935388351646 0.143587589971982 1.12451380470077e-06 6.66358270856608 6.47119275358153 1.02973021548123 0.303704951747597 -54.5445844632314 12.9754900048632 -4.20366278597481 3.18527307228143e-05 ZBTB11-AS1 other 0.00678419178375975 0.262753175732495 1 1.02973021548123 -4.20366278597481 4.17950808775944e-46 45.5058945217969 12.9711663846586 3.50823458525812 0.00049840006616994 -69.4476111489863 16.1776912452449 -4.2928011232381 2.18009133905731e-05 ZNF350 other 3.96050186396084e-42 0.181274594842615 1 3.50823458525812 -4.2928011232381 0.713253120721277 -8.98871445912012 13.4977701528188 -0.665940696674476 0.505799572861381 -21.9417898931013 32.6962396611701 -0.67107991990771 0.502523353220532 PGA5 other 1 1 1 -0.665940696674476 -0.67107991990771 0.964167500088471 22.5497898619103 90.6881933576741 0.248651880989336 0.803746885529266 39.4380618952196 216.441429562022 0.182211242898479 0.855501443294052 HP other 1 1 1 0.248651880989336 0.182211242898479 0.290837604202671 -1.25837886472631 4.67884138982744 -0.268950955991419 0.788095230708162 -8.51211389015856 6.4852895845074 -1.31252641524181 0.190036254061374 LINC02282 other 1 1 1 -0.268950955991419 -1.31252641524181 2.12164620173748e-97 701.794631220138 102.275007017238 6.86183899358574 2.34276718058247e-11 -1179.57199719231 135.027011781658 -8.7358224226994 5.23562642996129e-17 LSM14A other 2.08918501485089e-93 5.1125892088572e-13 2.23734265745626e-07 6.86183899358574 -8.7358224226994 0.0177398726605848 24.9466642940341 18.0169168586189 1.38462448873988 0.166873863277664 -41.8929888701946 31.3217390796697 -1.33750519930059 0.181753476587606 TMPO-AS1 other 1 1 1 1.38462448873988 -1.33750519930059 7.33508469078168e-10 490.563826913729 81.1498816361259 6.04515763945788 3.20315872873661e-09 29.4216772009531 152.285796365986 0.193200402815273 0.846891784512043 GATC other 5.25192063859968e-06 1 3.00456288755494e-05 6.04515763945788 0.193200402815273 2.1424480324739e-32 333.916581955365 34.5845525954948 9.65507883999238 4.03496634861698e-20 -241.013943480617 74.9748324907185 -3.21459795872773 0.00140311425264926 ZNF271P other 1.95776901207465e-28 1 3.94539009567768e-16 9.65507883999238 -3.21459795872773 1.54998179777249e-10 -145.447898539264 138.836992518958 -1.04761631536641 0.295393161866033 -699.229115344925 157.868918941004 -4.42917529324582 1.19631568619275e-05 FNTB other 1.13381168507058e-06 0.100945117600944 1 -1.04761631536641 -4.42917529324582 0.00111385074693284 6.60716364341839 4.85305518264082 1.36144416141237 0.174076499421997 -9.7424580463672 6.49926313293352 -1.49900963341514 0.134594816711507 LINC00609 other 1 1 1 1.36144416141237 -1.49900963341514 0.880170424369515 4.24325702990515 33.6036358603289 0.126273747505834 0.899573445091693 25.4552297660555 54.1904070968533 0.469736824832483 0.638777896902882 GALNT4 other 1 1 1 0.126273747505834 0.469736824832483 2.73792532352814e-08 155.099617747928 85.6851811497247 1.81011016918912 0.0709670537342985 -194.484156187481 101.4099798235 -1.9178009553495 0.0557892136868339 PSMA3-AS1 other 0.000182482722813151 1 1 1.81011016918912 -1.9178009553495 1.60489387595327e-18 289.535743032736 47.3298345753514 6.11740450036395 2.11420581812347e-09 120.013134345318 57.7854262959433 2.07687546909632 0.0383967703218118 INAFM1 other 1.35212309049063e-14 1 1.98735346903606e-05 6.11740450036395 2.07687546909632 6.88063419960589e-05 249.505196709815 86.6355207895573 2.8799410961686 0.00417347019929369 -142.406830057354 139.711493129721 -1.01929216320901 0.308629534451473 CNPY2 other 0.34795367147407 1 1 2.8799410961686 -1.01929216320901 0.965210137164539 -1.86548054695034 8.79875868443841 -0.212016332514 0.832193368543794 0.219918824736889 14.3222022304391 0.0153550984128331 0.987755909280037 LINC01481 other 1 1 1 -0.212016332514 0.0153550984128331 0.00045257990224312 207.870921039904 117.229505671191 1.77319626018852 0.0768910522389255 -311.079870565146 85.4325929420635 -3.64123175772163 0.000303772170970232 P2RX5-TAX1BP3 other 1 1 1 1.77319626018852 -3.64123175772163 2.60872478935746e-11 6.78124999999954 8.93143894429062 0.759256155956193 0.448108687790704 -71.660807291667 13.647389912668 -5.25088004008362 2.36827749191905e-07 BCDIN3D-AS1 other 1.94741305525534e-07 0.00212908146523523 1 0.759256155956193 -5.25088004008362 0.590452670639619 -40.9151361444777 39.8478087242557 -1.02678509695747 0.305090973797356 -37.7339941597069 78.3177652168872 -0.481806318849998 0.630185289505187 MAP1LC3B2 other 1 1 1 -1.02678509695747 -0.481806318849998 2.00864173330773e-15 -196.564889521707 155.993061154829 -1.26008739149371 0.208308780397045 -968.936959944562 177.376760184777 -5.46259250047864 7.88289771860293e-08 CHURC1 other 1.62639721145927e-11 0.000717422521370052 1 -1.26008739149371 -5.46259250047864 1.74197403370884e-07 302.453486858213 160.743668605552 1.88158880210954 0.0605547884443565 -241.041276735355 185.350294164588 -1.300463416159 0.194126019574371 VASH1-AS1 other 0.00110789548543882 1 1 1.88158880210954 -1.300463416159 6.01275223656702e-07 414.744529019984 82.2766702000315 5.04085213963636 6.79507466298407e-07 114.8648905804 61.501924612857 1.86766335043094 0.0624766237291374 C17orf49 other 0.00370445665294894 1 0.00612032374894975 5.04085213963636 1.86766335043094 2.62192163533075e-13 314.108683473392 78.0022804889249 4.02691666839139 6.66035087778621e-05 -854.663915822735 181.81040588003 -4.70085258148918 3.47585034615373e-06 PPT2-EGFL8 other 2.04667202853918e-09 0.0300278711404221 0.558537024611152 4.02691666839139 -4.70085258148918 0.143862918093557 -7.60283362763646 5.11891644505346 -1.48524276753594 0.1382038337865 -14.826993158873 7.54835902022923 -1.964267083632 0.0501353937163984 ZNF578 other 1 1 1 -1.48524276753594 -1.964267083632 2.30652806395807e-07 60.8527528809213 11.6934841026976 5.20398816524522 3.00927239496693e-07 -4.40326809340884 26.9891292890469 -0.163149690612503 0.870476169405248 PDF other 0.00145634181958312 1 0.00273151655291148 5.20398816524522 -0.163149690612503 1.99886363178103e-08 -149.373782548219 160.519205881761 -0.930566418689162 0.352591665219931 -1103.14389452066 221.88189753553 -4.97176158475933 9.54763965113217e-07 LINC00641 other 0.000134443567873592 0.00842388246419392 1 -0.930566418689162 -4.97176158475933 0.230863992379795 10.6470184386035 8.81081930831222 1.20840276778335 0.227545857228784 -4.66241663397402 15.2862135539495 -0.30500794833979 0.760505312128414 SPESP1 other 1 1 1 1.20840276778335 -0.30500794833979 0.0123553136024566 1.61265840374014 8.19690321409698 0.196739959179547 0.844122712149236 -15.8153841090721 9.70544935693438 -1.62953651370838 0.103921716663105 MIR1247 other 1 1 1 0.196739959179547 -1.62953651370838 0.355647086050701 9.47171602126059 62.5009889905748 0.15154505831402 0.879616025228656 -82.4963300430272 87.4021203635999 -0.943871037680045 0.345759486734181 LINC00645 other 1 1 1 0.15154505831402 -0.943871037680045 0.00290945325553322 10.5818867924534 65.2542484316953 0.162163951723848 0.871251699335403 -277.378199685533 103.741879277694 -2.67373409482059 0.00778224204077586 SPECC1L-ADORA2A other 1 1 1 0.162163951723848 -2.67373409482059 0.321187189064802 -17.8739801708816 13.3973991686962 -1.33413806260585 0.182851845993794 -10.6860532345446 15.7070016112803 -0.68033692865163 0.496650597791492 FAM181A-AS1 other 1 1 1 -1.33413806260585 -0.68033692865163 0.0453650632590185 -6.75984416147344 20.6146045144704 -0.327915296979304 0.743132396112054 -46.1619935904595 24.4615022267903 -1.88712831953153 0.059804077327454 TRIM6-TRIM34 other 1 1 1 -0.327915296979304 -1.88712831953153 3.13586577649697e-10 194.53882235529 88.3227539688401 2.20259008707906 0.0281450648890918 -457.729184488168 131.716236935272 -3.47511586375721 0.000561645175702743 BCL2L2-PABPN1 other 2.27444344769325e-06 1 1 2.20259008707906 -3.47511586375721 1.16498264668705e-24 85.1529952531328 61.7853017860798 1.37820796842523 0.168842694963836 -329.099264440266 70.4467314922295 -4.67160445160705 3.98219539464081e-06 SYNJ2BP-COX16 other 1.02961166314201e-20 0.0343305064971985 1 1.37820796842523 -4.67160445160705 0.0623203424037366 -2.62323425689411 19.1453907078986 -0.137016491170999 0.891080718411197 -37.8969564532125 22.7181179782175 -1.66813802488167 0.0960030142362682 TRIM34 other 1 1 1 -0.137016491170999 -1.66813802488167 5.77191335515997e-06 5.40223306452879 3.37465321906033 1.60082613348729 0.11014981713339 -6.76422936198404 3.95074815648137 -1.71213883904167 0.0875920683514942 LINC00638 other 0.0328306431641499 1 1 1.60082613348729 -1.71213883904167 3.02123338044261e-12 33.6345068115088 20.5501540547044 1.6367033902507 0.102415681121271 -109.167323033106 27.2401868410329 -4.00758348942978 7.21629592103921e-05 SLC25A21-AS1 other 2.30459682260162e-08 0.580334517969973 1 1.6367033902507 -4.00758348942978 0.000204940949853782 76.460538243784 19.2276108536166 3.97660108818993 8.17988899444078e-05 37.8403677276201 37.2563231992293 1.01567638667046 0.310345510601389 PRC1-AS1 other 0.97326457085561 1 0.683020731035805 3.97660108818993 1.01567638667046 1.28456721547327e-05 -13.4234129584196 19.681241195185 -0.682040976242067 0.495575198042662 -70.5933560557993 22.5366319494661 -3.1323827009329 0.00185077381454199 HIF1A-AS1 other 0.0706511968510296 1 1 -0.682040976242067 -3.1323827009329 0.197169363760378 77.5901846836397 45.4505774726526 1.7071330882501 0.0885076431354895 101.126141513668 63.1766480501331 1.60068861889319 0.110168534170687 RNASE4 other 1 1 1 1.7071330882501 1.60068861889319 0.219911223324913 34.5879414713853 35.4666627898662 0.975224020266942 0.32998990847693 -66.193436575433 73.1055775979139 -0.905449881533004 0.365727173054095 MC1R other 1 1 1 0.975224020266942 -0.905449881533004 0.00115125817232526 -8.97200843942542 4.82195582296418 -1.86065753582746 0.0634624664422554 -17.6429347782652 5.44220032906293 -3.24187529151523 0.00127814735551334 TGFB3-AS1 other 1 1 1 -1.86065753582746 -3.24187529151523 0.00252135857623344 11.7185844263618 4.52921347146038 2.58733320922128 0.00999409168565206 4.50951338482741 5.25854235383834 0.85755958236902 0.391605758964397 FOXN3-AS1 other 1 1 1 2.58733320922128 0.85755958236902 0.045278081087891 720.603483492401 433.672809260145 1.66162938534644 0.0973059071624074 -892.800961859843 893.907086700346 -0.99876259528875 0.318463683671642 TUBB3 other 1 1 1 1.66162938534644 -0.99876259528875 2.67702628514014e-18 76.8468027876273 24.8146032852998 3.09683785406923 0.00208252703902109 -161.507089679237 37.7718516391152 -4.27585841494691 2.34209468055615e-05 UBE2F-SCLY other 2.24896978214623e-14 0.194487542273383 1 3.09683785406923 -4.27585841494691 0.0350133630722629 346.027552822537 254.64214960382 1.35887775594456 0.17492161967005 -70.0077643872269 286.665617192727 -0.244214025640056 0.807185465504054 TMEM179 other 1 1 1 1.35887775594456 -0.244214025640056 0.0385655643286951 -26.6548193272069 13.4995232109907 -1.97450079611003 0.0489525480023812 -15.1167304253815 10.0194355747289 -1.50874071824057 0.132086028698669 TVP23C-CDRT4 other 1 1 1 -1.97450079611003 -1.50874071824057 1.13337568953304e-25 21.2734366742996 8.0237015507045 2.65132452146501 0.00830906785836948 -38.5487651928833 10.3080600819309 -3.73967214844389 0.000208784197994506 FPGT-TNNI3K other 1.00666428744324e-21 1 1 2.65132452146501 -3.73967214844389 0.00276919653252757 405.677292463929 126.848349276263 3.19812827505075 0.00148403349210374 126.903161050914 223.522469557835 0.567742300368954 0.570502195691627 BLOC1S5-TXNDC5 other 1 1 1 3.19812827505075 0.567742300368954 0.0194232887240523 -45.8760507113955 33.6559910835959 -1.36308720184311 0.173560154391862 -120.785276808105 44.612584557604 -2.70742612215499 0.00704781445059509 LINC00639 other 1 1 1 -1.36308720184311 -2.70742612215499 0.946234140063643 4.31173882547989 33.1785035184259 0.129955795718313 0.896661333333363 17.3268641539447 53.5048237042252 0.323837421644966 0.746216406250991 POC1B-GALNT4 other 1 1 1 0.129955795718313 0.323837421644966 0.00629093630460476 3.65667067464776 10.339934026185 0.353645455124526 0.723776728642999 -44.5214405206893 17.9792274833513 -2.47627105012805 0.0136574836504307 LRP1-AS other 1 1 1 0.353645455124526 -2.47627105012805 0.00116732084108176 34.2064508478596 9.35667085042749 3.6558356486695 0.000287847221808561 27.5897268666743 12.435291696673 2.2186634250048 0.0270274889797577 LINC00648 other 1 1 1 3.6558356486695 2.2186634250048 0.544768371788782 -2.65517324408269 3.17042874249638 -0.837480814027702 0.402779090053651 1.15345966466821 6.23271366613236 0.185065402721119 0.853263400189746 LINC00924 other 1 1 1 -0.837480814027702 0.185065402721119 6.3544643362495e-07 26.5548006903042 17.9317289042735 1.48088345703106 0.139359902671665 226.390180112287 41.9867420610735 5.39194443291128 1.14451781521659e-07 ITGB3 other 0.00390799556679344 0.0010372764959308 1 1.48088345703106 5.39194443291128 0.726006132068192 1.72883719592842 2.17038621199121 0.796557399036509 0.426140653284171 1.98744896198741 3.97749769248079 0.499673190444475 0.617556697423207 ANKRD34C-AS1 other 1 1 1 0.796557399036509 0.499673190444475 4.33244453371108e-08 22.1977077363897 16.3714756665263 1.35587702590402 0.175838523337357 -105.768958930277 27.5318149718473 -3.8416994679948 0.000140281908307159 USP3-AS1 other 0.000285291472544875 1 1 1.35587702590402 -3.8416994679948 0.452765787100821 -39.8957141471947 63.9489011434686 -0.623868642522709 0.533039369472872 -122.791719189375 98.6183522414787 -1.24512036957082 0.213754760314407 BUB1B-PAK6 other 1 1 1 -0.623868642522709 -1.24512036957082 5.85319233404104e-05 -47.8618077214906 133.092403324495 -0.359613370304825 0.719309600036165 -1004.03604695271 253.29901561764 -3.96383714521938 8.61091046738734e-05 ZNF710-AS1 other 0.298746936729455 0.688786728286313 1 -0.359613370304825 -3.96383714521938 0.0410319458030788 2.49903241775552 2.66259796822533 0.938569189783155 0.348471617678004 -8.07923673512255 5.22024090382875 -1.54767507553088 0.122426064048964 ACTG1P17 other 1 1 1 0.938569189783155 -1.54767507553088 0.000874356045327108 6.01044482143979 18.1127033237101 0.331835878610783 0.740172280695123 -99.046200184023 33.1937400249841 -2.98388190392145 0.00300570670139777 ST20-MTHFS other 1 1 1 0.331835878610783 -2.98388190392145 0.233529554353189 2.50129160978684 4.48768743672539 0.557367607493628 0.577562316940596 -9.71748398613889 8.79847795287198 -1.10445056954049 0.270006870360556 UBE2Q2P2 other 1 1 1 0.557367607493628 -1.10445056954049 5.4905439448742e-15 153.170764373864 56.2063023125886 2.72515284001448 0.00668463328004789 -367.126227355349 84.437301217006 -4.34791522305793 1.71091002214297e-05 THTPA other 4.41220111410091e-11 0.143100514252038 1 2.72515284001448 -4.34791522305793 0.227084229217817 -4.18155743238179 2.78960414663727 -1.49897878429183 0.134602817712765 -8.19668771845609 5.469246895532 -1.49868672506853 0.134678584215755 CPEB1-AS1 other 1 1 1 -1.49897878429183 -1.49868672506853 8.35000494129969e-06 42.7592060916243 26.4868737296912 1.61435458665294 0.107170665528375 -159.96916739483 51.3198958694235 -3.11709844076555 0.00194666791902509 MRPL46 other 0.0468268277108087 1 1 1.61435458665294 -3.11709844076555 3.64015967262979e-06 28.871596778366 10.8273264503777 2.6665490239614 0.00794844688389297 -32.4118773779316 17.3540796806535 -1.86768056701184 0.0624772805974418 ANP32AP1 other 0.0211129261012528 1 1 2.6665490239614 -1.86768056701184 0.0123123842020127 1.05810469697335 1.5169980883366 0.697499031217348 0.485861462913425 -4.3599489254287 2.36134616655633 -1.84638279095989 0.0655126522281311 INO80-AS1 other 1 1 1 0.697499031217348 -1.84638279095989 0.000102424106742572 27.8385792316746 12.8455488332471 2.16717709714529 0.0307608438972006 -40.825572622748 22.28621378008 -1.83187566203996 0.0676504059451216 IQCH-AS1 other 0.50699932837573 1 1 2.16717709714529 -1.83187566203996 0.662047652716201 -5.34874476492372 31.8764886207679 -0.167795920954699 0.866821278765349 -53.8390948741597 63.1091825379576 -0.853110319433748 0.394064407157862 HSP90B2P other 1 1 1 -0.167795920954699 -0.853110319433748 0.0140241457788087 4.2049030349209 2.2874989473601 1.83820982290444 0.0667100316572334 -4.43998565128155 4.43236555750839 -1.00171919343617 0.317033576144928 CRTC3-AS1 other 1 1 1 1.83820982290444 -1.00171919343617 0.312737822213771 -4.01145305517209 4.95813160287407 -0.809065465879682 0.418924924541305 -14.6623110102529 9.65849814347364 -1.51807359616882 0.129730697085575 LYPD8 other 1 1 1 -0.809065465879682 -1.51807359616882 0.00112507531598215 211.94890695864 112.84809401484 1.87817888116717 0.0610238308252043 -256.995322598581 174.292831084084 -1.4745031163938 0.141067858150942 RBM15B other 1 1 1 1.87817888116717 -1.4745031163938 0.00052895143452889 592.499077901455 627.948002959896 0.943547993000456 0.345922028012563 -3703.59963661138 1247.26899703658 -2.96936718976488 0.00314840772363377 MIR568 other 1 1 1 0.943547993000456 -2.96936718976488 0.000749722232590039 20.5431958167588 12.8417619428933 1.59971785087696 0.110382223863246 107.729725394584 28.9989782466586 3.71494900538427 0.000229533045112067 HOXB7 other 1 1 1 1.59971785087696 3.71494900538427 0.181752576341925 -138.347400972404 176.798414411997 -0.782514941847893 0.434334853019598 -676.257382382376 365.715254875713 -1.84913637964651 0.065111722453382 FRRS1L other 1 1 1 -0.782514941847893 -1.84913637964651 0.120023645730987 12.4201532115497 6.3370860792141 1.95991549685404 0.0506393306982407 -1.65140595016843 13.7669497335227 -0.119954382207646 0.904574286422539 TBC1D3G other 1 1 1 1.95991549685404 -0.119954382207646 8.36928373977105e-06 48.4878991228073 35.7603791893964 1.35591121296568 0.175827652448295 -225.126809941521 72.1221282923164 -3.12146653561117 0.00191892231318622 MRC1 other 0.0469265739288963 1 1 1.35591121296568 -3.12146653561117 0.0891017523129945 1.68166673973086 2.62803072576355 0.63989614856663 0.522574681952844 -10.8856545818538 5.80224571147511 -1.87611058255 0.0613048831319065 HSPB9 other 1 1 1 0.63989614856663 -1.87611058255 0.0642840186828017 19.3817673084617 8.28760821258446 2.33864425191229 0.0198048526995026 14.3199351359307 23.728305804577 0.603495894475893 0.54649267329019 SCX other 1 1 1 2.33864425191229 0.603495894475893 0.0100602520628267 17.0867843220938 9.394337904798 1.8188385914208 0.0696203531441846 -21.9655204717316 17.4626235496784 -1.25785913034449 0.20911442005495 NBAT1 other 1 1 1 1.8188385914208 -1.25785913034449 0.508638011321922 1.6339104395417 8.47120838024008 0.192878083763464 0.847143851152931 -17.4493282391948 17.9998068391168 -0.969417527374478 0.332871913224209 C16orf95 other 1 1 1 0.192878083763464 -0.969417527374478 0.0199662177145454 -8.17542613636379 5.92232460313528 -1.38044208722293 0.168156253250335 -25.2131717566292 9.04941225624573 -2.78616677444743 0.00556570669073805 CISTR other 1 1 1 -1.38044208722293 -2.78616677444743 0.0192021891213424 7.56679856265996 10.2377597591389 0.739106869147361 0.460238908332637 66.5221892870618 23.5942756797532 2.81942070144353 0.00502976596553174 MT1L other 1 1 1 0.739106869147361 2.81942070144353 5.14214000644054e-13 7.16880688806891 1.40741948129595 5.09358224988324 5.23126920013819e-07 -5.59381713817136 2.83807879301888 -1.97098725797573 0.0493544987252619 STAM-AS1 other 3.98464429099078e-09 1 0.00472278983388476 5.09358224988324 -1.97098725797573 0.511102650160273 -4.64502805218059 13.9462056895349 -0.33306751352923 0.739242689401703 -34.0771979944704 29.6331995723029 -1.1499668779041 0.250785003321651 SNAI3-AS1 other 1 1 1 -0.33306751352923 -1.1499668779041 0.0471367355166984 14.2148679561726 6.55695777012084 2.16790597934728 0.0307150385850716 -5.09027567964179 15.3016602613481 -0.332661658454134 0.739552189520932 ANKRD20A1 other 1 1 1 2.16790597934728 -0.332661658454134 0.0599967733403202 -0.660439991550239 2.82436825196857 -0.233836360074475 0.815221524220996 -10.1668829405197 4.90010006377681 -2.07483169898441 0.0385868136229541 ADPGK-AS1 other 1 1 1 -0.233836360074475 -2.07483169898441 0.697918338989907 1.05284656929012 3.07823271799689 0.342029555833985 0.732497319939848 -1.66136811580391 4.35131960145714 -0.381807880820236 0.702794250747566 LINC00565 other 1 1 1 0.342029555833985 -0.381807880820236 0.121134409900265 -1.06310998573699 2.77932533741053 -0.382506492286895 0.702272532872409 -4.79699193897344 3.49683699345944 -1.37180885124066 0.170830030231391 LINC00622 other 1 1 1 -0.382506492286895 -1.37180885124066 5.36328677280845e-06 22.9683137739347 8.42142914430678 2.72736531773377 0.00664072827528508 -11.5239962940086 12.3294506547529 -0.934672323747542 0.350472192924114 CAPN10-AS1 other 0.0306511839066003 1 1 2.72736531773377 -0.934672323747542 0.357042945629878 -31.4689699979909 36.059989301523 -0.872683841774235 0.383313579530822 -121.08217960171 89.3473916229566 -1.3551842689787 0.176057318934122 LINC01572 other 1 1 1 -0.872683841774235 -1.3551842689787 0.000236103285408514 1.20758336520318 1.7370183852267 0.695204711402967 0.487299066087145 -4.17948654683623 2.01945530410956 -2.06961081947744 0.0390799952373968 LMO7-AS1 other 1 1 1 0.695204711402967 -2.06961081947744 0.00438963671313421 12.3648439529655 10.0183283346319 1.23422227141649 0.21782022215823 -21.3909161762549 15.0540328146689 -1.4209425766238 0.156086198855891 RBFADN other 1 1 1 1.23422227141649 -1.4209425766238 0.00412894694336238 13.105696778757 4.40810153142582 2.97309322059057 0.00311081828572198 -4.66831670892141 12.6216430539173 -0.369866006270281 0.711661099297059 EPPK1 other 1 1 1 2.97309322059057 -0.369866006270281 3.65670388924178e-51 135.611640096091 37.2405549222389 3.64150427885025 0.000303692162675248 -209.833253257625 46.0766095481588 -4.55400810335903 6.84309566411195e-06 ZNF865 other 3.49836861083761e-47 0.0583989783975314 1 3.64150427885025 -4.55400810335903 0.626310656618724 -1.85818478360748 4.04985710611988 -0.45882724622543 0.646586867342879 1.78995911053937 5.07784729907932 0.352503532523302 0.72463100438343 LINC01616 other 1 1 1 -0.45882724622543 0.352503532523302 5.39441810377583e-08 22.0045951615159 5.97885176743402 3.6804048699404 0.000262103171088195 -5.17473360369181 8.45101611255173 -0.612320877723345 0.540645415362237 MANEA-AS1 other 0.000352848888167977 1 1 3.6804048699404 -0.612320877723345 0.0554827726245565 -1.26041576813534 12.1383998088521 -0.10383706155536 0.917346291270171 -57.8709796141348 25.7927065103086 -2.24369550326196 0.0253520694595103 VPS9D1-AS1 other 1 1 1 -0.10383706155536 -2.24369550326196 0.0748843892678503 0.73788363460819 5.25122979241204 0.140516348317954 0.888316781089581 -16.283504843528 9.11055115520795 -1.78732379261376 0.0745780752135818 TMEM202-AS1 other 1 1 1 0.140516348317954 -1.78732379261376 0.264669184575696 -2.45107538486542 5.04480822541458 -0.485860963458922 0.627308713538887 -15.5788540065003 9.87564857279705 -1.57750186143855 0.115402020857939 DLGAP1-AS5 other 1 1 1 -0.485860963458922 -1.57750186143855 0.055659800259198 34.9729149488952 14.7019598907062 2.37879270579451 0.0177971632134964 14.6142674901603 35.0880779483133 0.416502366179416 0.677246461666103 SMG1P7 other 1 1 1 2.37879270579451 0.416502366179416 0.000347948074443516 13.3320261906348 3.61216890301364 3.69086456048937 0.000251939015856247 -1.74621807440464 10.0215385972894 -0.174246504910628 0.861752988816616 TMEM249 other 1 1 1 3.69086456048937 -0.174246504910628 0.102763836768941 6.02805038967461 4.81366789014384 1.25227799824273 0.211139898000125 -3.91818894066227 7.3416589314509 -0.53369258600085 0.593826209321432 C15orf65 other 1 1 1 1.25227799824273 -0.53369258600085 0.189640932117951 -2.0612063519258 1.62171991763197 -1.27100020756702 0.204403171161884 -6.27600681022381 3.74288207973493 -1.67678454103696 0.0942981245084106 BEAN1-AS1 other 1 1 1 -1.27100020756702 -1.67678454103696 0.0346266903520139 -26.9649631150261 91.234870241214 -0.295555449837699 0.767710950675581 -637.731919707993 253.120437634631 -2.51948015603754 0.0121109157983999 SCRT1 other 1 1 1 -0.295555449837699 -2.51948015603754 0.265157699241731 109.716999742689 78.8992692295428 1.39059589289081 0.165055738643511 -64.7184617423905 188.305334919279 -0.343688944182774 0.731245524210287 HPR other 1 1 1 1.39059589289081 -0.343688944182774 0.00250383274451184 7.14002515359978 138.150527151586 0.0516829381748602 0.958805002208872 -557.87119087873 210.702955561977 -2.64766666129956 0.0083987139516468 DNAAF4-CCPG1 other 1 1 1 0.0516829381748602 -2.64766666129956 4.05833924223147e-05 3.98855645939626 30.3021809949813 0.131626052265243 0.895340794589785 -250.428522187863 61.9119837492798 -4.04491193824452 6.19056151050244e-05 ISY1-RAB43 other 0.211480057912682 0.500135464433492 1 0.131626052265243 -4.04491193824452 3.01865044237693e-33 49.9796734632733 11.59639466574 4.30993208699005 2.02140023096088e-05 -57.3206498576793 15.8383113424907 -3.61911371851245 0.000330364450901119 MIA other 2.76689499548269e-29 1 0.173314855802586 4.30993208699005 -3.61911371851245 0.000173188015740274 -1788.23112567801 2829.68907381172 -0.631953221372543 0.527747904075418 -24446.3373746507 5965.88759418631 -4.09768655354375 4.97476872911758e-05 PCDHGA9 other 0.832514791663498 0.404995922237462 1 -0.631953221372543 -4.09768655354375 9.79472757222237e-14 52.4026188442923 6.57039390066181 7.97556731553248 1.3351299277586e-14 2.6910941091493 5.13251949473426 0.524322238212683 0.600319667205608 SNORD3B-2 other 7.71334796312511e-10 1 1.29387441299086e-10 7.97556731553248 0.524322238212683 0.000189864159892911 -1844.8649977395 2798.78603471554 -0.659166143769545 0.51013627173302 -24088.3034481342 5900.73412581666 -4.0822553489987 5.30391284314143e-05 PCDHGB3 other 0.907170955968327 0.431102035890536 1 -0.659166143769545 -4.0822553489987 2.74228315957224e-13 68.4254995161823 12.7319876638253 5.37429828891494 1.25205908608038e-07 17.7818922519137 18.0089545568948 0.98739169982001 0.323995779037415 CCER2 other 2.13870663615039e-09 1 0.00114413159286025 5.37429828891494 0.98739169982001 0.000194029627256128 -1841.00406871599 2803.91956437846 -0.656582339987373 0.511795100742353 -24099.066085813 5911.5572445875 -4.07660199990072 5.42960039378497e-05 PCDHGA4 other 0.925909381266243 0.440774959967464 1 -0.656582339987373 -4.07660199990072 0.000239421370756608 -1086.4407171714 648.420816581173 -1.67551794974705 0.0945463332731583 -3050.45753786789 790.615121449212 -3.85833442228671 0.000131323581771025 SPON1 other 1 1 1 -1.67551794974705 -3.85833442228671 0.000121872933247025 170.129562109277 44.7395216615621 3.80266832972074 0.000163453492814915 -77.7670568632318 34.3428487114136 -2.26443232815997 0.0240356128969534 OVCA2 other 0.597664864643411 1 1 3.80266832972074 -2.26443232815997 2.37594951879424e-07 360.299295381937 64.6255337444013 5.5751848303017 4.34165093440815e-08 69.2973845112905 171.273631352894 0.4046004277711 0.685969657661519 MRPL12 essential 0.00149922414635916 1 0.000399735801530958 5.5751848303017 0.4046004277711 2.10868974884714e-05 1.69415182819089 3.01749154338555 0.561443770042879 0.574782195783907 -10.5593312491505 2.25557909635921 -4.6814280493176 3.80469306878494e-06 ALOX12P2 other 0.113342074000534 0.0328453475554189 1 0.561443770042879 -4.6814280493176 3.67575172351396e-27 51.2433582431724 28.607161384177 1.79127728036365 0.0739422741454963 -144.429973669361 35.6474804011552 -4.05161801182114 6.02202090726301e-05 ZNF234 other 3.28943021737264e-23 0.48700083077036 1 1.79127728036365 -4.05161801182114 0.122060286174215 60.9118328722944 30.1029983249167 2.02344737274482 0.0436366157405111 72.2605923378445 46.3401906326414 1.55935034688755 0.119639016292343 MYZAP other 1 1 1 2.02344737274482 1.55935034688755 0.00352573776697367 15.1125618475768 5.65941286338326 2.67034093684098 0.00786068514596618 29.3199126194287 9.0974808423838 3.22286060585383 0.00136440585260046 TAPT1-AS1 other 1 1 1 2.67034093684098 3.22286060585383 0.241138985801559 1.2885609528364 3.29610509911526 0.390934425356242 0.696072551713902 -1.93302361595047 4.04485995443575 -0.477896302399948 0.633008530831142 PPIAL4A other 1 1 1 0.390934425356242 -0.477896302399948 0.000999823801139391 -0.292390076718895 6.27106993478759 -0.0466252297868528 0.962833222758342 -17.5610369282532 4.69636320683588 -3.73928424076994 0.000209096539840973 TMEM220-AS1 other 1 1 1 -0.0466252297868528 -3.73928424076994 6.1935790552351e-20 330.186652227622 49.0945869222351 6.72552052939425 5.48069241862542e-11 -263.096758836308 98.0674241307152 -2.6828150241371 0.0075768138451841 LINC00667 other 5.28621972364316e-16 1 5.22474408267562e-07 6.72552052939425 -2.6828150241371 0.00235158056852598 -76.9890703009089 84.5265408232916 -0.91082717393889 0.362888568898006 -693.374011604377 198.320300188315 -3.49623316899976 0.000520135570234027 LINC00672 other 1 1 1 -0.91082717393889 -3.49623316899976 0.0872082600120065 -6.340604980115 4.16783513086834 -1.52131856971847 0.128903133234848 -17.7362428825609 8.15964768781821 -2.17365302536774 0.0302674129799846 DLGAP1-AS4 other 1 1 1 -1.52131856971847 -2.17365302536774 7.73795988885808e-10 183.120922288641 27.6341799743146 6.62660959937467 1.01089956512958e-10 3.20800525163091 21.5866764738228 0.148610429007964 0.881929437609488 SNORD3A other 5.53264132053353e-06 1 9.61466576394746e-07 6.62660959937467 0.148610429007964 2.72849836220241e-15 77.7542254772291 26.6027045186945 2.92279401226251 0.0036499898239338 -151.231956096888 39.6514846225194 -3.81403010597486 0.000156487695026227 LINC00909 other 2.20408097698711e-11 1 1 2.92279401226251 -3.81403010597486 0.00908718840351212 54.6805103148763 32.7604050743352 1.66910360817588 0.0958130394222228 -174.901954397394 76.069264881714 -2.29924601834082 0.0219618048051592 MAPT-AS1 other 1 1 1 1.66910360817588 -2.29924601834082 0.816714845062229 1.50155318717101 2.36508754881025 0.63488270779928 0.525836411726988 1.68784268886518 3.90589311862969 0.432127208195941 0.665861616463123 L3MBTL4-AS1 other 1 1 1 0.63488270779928 0.432127208195941 7.14235030857099e-11 88.5026473099907 12.6370308886241 7.00343681122606 9.45389288898191e-12 2.92340635656446 9.87152496060991 0.296145364391991 0.767259431220964 SNORD3C other 5.27814737704459e-07 1 9.05872016622247e-08 7.00343681122606 0.296145364391991 9.6744187921658e-08 17.278756088423 12.6607958104868 1.36474486652025 0.173033926177783 -40.5428999625324 16.4928734918809 -2.45820717551074 0.0143494198163059 AGAP12P other 0.000624967453973911 1 1 1.36474486652025 -2.45820717551074 1.2750877472913e-14 55.8150298889834 6.75616735170202 8.26134507679453 1.72539241370248e-15 2.91256731556846 5.27763801783709 0.551869473754113 0.581319240295539 SNORD3B-1 other 1.01854009253629e-10 1 1.67432079825688e-11 8.26134507679453 0.551869473754113 2.68097932600803e-10 18.7434762004849 8.17986351175308 2.29141674229084 0.0224132046799886 -23.7364057320924 10.6556851638388 -2.22758136779834 0.0264157548463847 RBP3 other 1.94692718654703e-06 1 1 2.29141674229084 -2.22758136779834 3.39112681190405e-18 108.224937671957 42.0238724964097 2.57532043676373 0.0103424911580672 -195.991420649073 54.3784237529083 -3.60421297865572 0.000349145586942519 TIMM23 essential 2.8451553951875e-14 1 1 2.57532043676373 -3.60421297865572 2.98751554643525e-07 11.8114712064604 6.43712075530529 1.83489974096349 0.0671985406720693 -27.580998912388 10.0161870838916 -2.75364254694731 0.00613881457877316 MIR1539 other 0.00187257474450561 1 1 1.83489974096349 -2.75364254694731 2.26284665674174e-05 38.3112715603695 8.31020214841426 4.61014917280682 5.28717101190678e-06 7.1670677898118 18.2014349289846 0.393763888274473 0.693946984401457 RARA-AS1 other 0.12117543846852 1 0.0463896384584701 4.61014917280682 0.393763888274473 8.43556139540883e-08 779.799595761512 272.689624624943 2.85965994061581 0.00444360014224326 -817.244607492307 424.306207682764 -1.92607271045001 0.0547421701291582 RPL17 essential 0.0005467930896504 1 1 2.85965994061581 -1.92607271045001 0.00177433030866001 24.1485457089715 9.71196735137291 2.48647311459071 0.0132749413946525 -52.1703469320838 25.6114956557546 -2.03698946884275 0.0422545982300932 MAFG-AS1 other 1 1 1 2.48647311459071 -2.03698946884275 6.76212061570136e-07 -75.2577183117989 302.050416921831 -0.249156147767461 0.803356793813689 -1409.61129917245 393.47284238921 -3.58248688934447 0.000378515052448577 ZNF488 other 0.00414720857360965 1 1 -0.249156147767461 -3.58248688934447 5.98795006428954e-72 56.3626131759319 48.4225816206787 1.16397373476392 0.245084612356721 -613.798741251741 60.1206816419955 -10.2094441461387 4.831666633392e-22 SEC22B other 5.8526223928366e-68 4.74759563397098e-18 1 1.16397373476392 -10.2094441461387 0.0103310656768059 5.60038434814177 2.10131888826841 2.66517584713511 0.00798929506795531 -1.91302714849987 4.90414892441992 -0.390083412633345 0.696671214909409 MIR4477B other 1 1 1 2.66517584713511 -0.390083412633345 1.71656499949409e-11 12.1388634543192 3.00060981989398 4.04546548299574 6.17186004181149e-05 -10.7170550021922 4.95544499107965 -2.16268266956532 0.0311061160331646 NDUFV2-AS1 other 1.28742374962057e-07 1 0.518312806311329 4.04546548299574 -2.16268266956532 4.34471747550152e-08 499.677609410623 85.2216973071778 5.86326751519108 9.01222308675318e-09 54.8660716087242 224.723973245839 0.244148725283987 0.80723127911931 BAHCC1 other 0.000286012751412265 1 8.39488580531059e-05 5.86326751519108 0.244148725283987 3.54354790173778e-24 -333.11647880845 281.63577611444 -1.18279177242415 0.237534785753439 -2831.63625031264 364.433562824051 -7.76996561010972 5.65896715894016e-14 NCOA4 other 3.12115699185064e-20 5.47165534597924e-10 1 -1.18279177242415 -7.76996561010972 0.000355304049028748 39.8188179419673 104.169980967443 0.382248490132796 0.702462458456708 -299.673181436626 135.699393897865 -2.20836050057952 0.0277364026358436 GDF10 other 1 1 1 0.382248490132796 -2.20836050057952 0.0218867505767521 294.720086460269 137.569649452417 2.14233362978953 0.0327198705472919 155.533103428574 181.654266031352 0.856203968266457 0.392355275262892 FXYD1 other 1 1 1 2.14233362978953 0.856203968266457 0.000216841037990319 142.994220430108 49.8514756717913 2.86840496701729 0.00432528873172239 -254.940053763444 112.788686840047 -2.26033355743374 0.0242919062603984 AARSD1 other 1 1 1 2.86840496701729 -2.26033355743374 8.09609166077255e-13 -124.459551836512 38.3707660737497 -3.2436035182956 0.00127145158763033 -311.28858676463 48.9316491200128 -6.36170234118094 5.07109923698184e-10 LINC01532 other 6.2469443254521e-09 4.76886172245772e-06 1 -3.2436035182956 -6.36170234118094 3.13045958751819e-17 38.2103506117616 9.09457692127453 4.20144344728977 3.21820721566605e-05 -8.54475069069857 11.948746105105 -0.715116934909836 0.474919534353878 ZNF850 other 2.59765536572259e-13 1 0.273644159548084 4.20144344728977 -0.715116934909836 0.0492771300644727 4.99018817204309 2.43408009953605 2.05013309668579 0.0409475883312032 -4.72768817204302 5.50709270669615 -0.858472595947869 0.391102170398276 PTGES3L other 1 1 1 2.05013309668579 -0.858472595947869 0.000214728592799283 38.4304358602424 11.4487622090115 3.35673282042605 0.000857479934993915 -41.6515271564452 25.902596325338 -1.60800587837991 0.108554443747328 ASB16-AS1 other 1 1 1 3.35673282042605 -1.60800587837991 0.743273223653111 5.20896590286043 6.76054607597977 0.770494845285929 0.441425629396531 5.84526488933781 8.99557629308377 0.649793264921996 0.516169541086298 PCAT19 other 1 1 1 0.770494845285929 0.649793264921996 1.25847448393059e-09 28.217379187228 19.5897545521566 1.44041514721897 0.150469317327435 -119.966617164418 30.7308626613488 -3.90378293269664 0.000109727652540668 CHMP1B-AS1 other 8.93013493797146e-06 0.869152735774633 1 1.44041514721897 -3.90378293269664 0.000512725167063849 -5.87184691214877 8.23918945873438 -0.71267288385073 0.476450640092155 -41.0983437228187 12.3817835263277 -3.31925878331099 0.000982658442888445 PARD6G-AS1 other 1 1 1 -0.71267288385073 -3.31925878331099 0.289348936810491 2.11536774786155 5.13326983784003 0.412089723448407 0.680475263998363 7.72294336417026 6.62333936229463 1.16601957739558 0.244241057784539 LINC01140 other 1 1 1 0.412089723448407 1.16601957739558 0.00930691963069101 28.1224212812162 9.19637293012654 3.05799052462189 0.0023651415744024 16.9885993485343 21.3538668641452 0.795574846308489 0.426711108631083 MAP3K14-AS1 other 1 1 1 3.05799052462189 0.795574846308489 3.09810542002858e-06 -6.53420005457064 5.14344641582606 -1.27039333674505 0.204618952011694 -24.0002435536119 6.61066180871008 -3.63053567828711 0.000316255804937238 CEBPA-AS1 other 0.0180557583879266 1 1 -1.27039333674505 -3.63053567828711 0.00120745197046049 -38.7146999863018 22.2185247567058 -1.74245141881516 0.0821378217242349 -89.6100236738678 28.333785550954 -3.16265623994075 0.00167311352843998 LINC00906 other 1 1 1 -1.74245141881516 -3.16265623994075 6.96104643110143e-46 124.801385212371 20.062912221402 6.22050198072637 1.16071042039017e-09 -36.9895331025595 24.599940766369 -1.50364317759369 0.133395592732301 DM1-AS other 6.59141486560995e-42 1 1.09362135809162e-05 6.22050198072637 -1.50364317759369 1.14451886761902e-42 72.208659416607 12.2293429797983 5.90454119537645 7.10955776580464e-09 -20.1795267442186 15.3468533636083 -1.31489669355087 0.18923421231649 ZNF582-AS1 other 1.07596218744864e-38 1 6.63179548394257e-05 5.90454119537645 -1.31489669355087 0.266106810701726 27.7656491194791 19.6525125902221 1.41282947877583 0.158417675945699 19.8223957273577 26.1952706269276 0.75671658482433 0.449627444039716 ZNF571-AS1 other 1 1 1 1.41282947877583 0.75671658482433 2.27680700861175e-26 68.7640689913445 12.9915527617539 5.29298308311387 1.91264898372257e-07 -13.572335562812 16.6276690834095 -0.816250040503514 0.414803894114838 ZNF285 other 2.02886272537393e-22 1 0.00174184942947614 5.29298308311387 -0.816250040503514 7.35987240822708e-42 193.548491491033 49.6090668445854 3.90147414176079 0.000110707219000016 -230.32369519634 61.845573391782 -3.72417430326462 0.000221672670741972 ZNF224 other 6.903560318917e-38 1 0.917984259948129 3.90147414176079 -3.72417430326462 0.146231283746041 -8.9944865408452 5.61070601520552 -1.60309353519314 0.109639822432244 -16.7910556841834 8.80163329905036 -1.90772043252416 0.0570855540411498 LDLRAD4-AS1 other 1 1 1 -1.60309353519314 -1.90772043252416 0.000543677224010402 -16.8452878714955 7.17200513591565 -2.34875568997272 0.0192808672262918 -5.50832654591211 8.79388294045429 -0.626381609035559 0.531391719491121 EML2-AS1 other 1 1 1 -2.34875568997272 -0.626381609035559 3.74003969442657e-39 106.364733600777 18.4941778114806 5.75125505361742 1.67125969179016e-08 -60.3929685395656 24.4337581048968 -2.47170199034844 0.0138289725996457 LIN37 other 3.48422097932779e-35 1 0.000154992623816619 5.75125505361742 -2.47170199034844 1.78727464682635e-47 59.9185860640851 9.70434953963489 6.17440517979729 1.52459289756662e-09 -20.8078670786291 12.0524930630424 -1.72643676041052 0.0849788608948483 MZF1-AS1 other 1.69773218702035e-43 1 1.43403207945117e-05 6.17440517979729 -1.72643676041052 0.0556671119992365 -6.87385067823734 11.1957421846814 -0.613970075842091 0.539554578120549 -22.3271435731967 12.7666227342588 -1.74886843904948 0.0810158511143061 CCDC177 other 1 1 1 -0.613970075842091 -1.74886843904948 1.15321116780831e-20 14.5575679194913 5.72092636202222 2.54461725222163 0.0112819435966021 -15.7359910435966 6.98063776254145 -2.25423400825021 0.0246748689420547 CARD8-AS1 other 9.91761604315147e-17 1 1 2.54461725222163 -2.25423400825021 9.4524751060424e-78 44.493961287873 15.8795357938036 2.80196863848093 0.00530437800231903 -159.140690291788 19.3938891936806 -8.20571308325529 2.5799642313037e-15 PTOV1-AS1 other 9.26720659396397e-74 2.50746723640406e-11 1 2.80196863848093 -8.20571308325529 3.20738117029407e-35 18.9023340214584 8.81882080419598 2.1434083355526 0.0326317468282637 -47.4627169723772 10.7669786757165 -4.40817414075715 1.31357622897965e-05 NAPA-AS1 other 2.9568847008941e-31 0.110524303906348 1 2.1434083355526 -4.40817414075715 5.72892948604886e-06 2.6416966832184 2.99834293078818 0.881052215906461 0.378777208249972 -5.61621802811138 3.75521132178111 -1.49557975486918 0.135489981204422 ZNF649-AS1 other 0.0326033377051041 1 1 0.881052215906461 -1.49557975486918 0.423264980474934 -1.79379891249129 5.56422334598528 -0.322380824951169 0.747318381125823 2.04397446617795 6.98265801476527 0.292721548421223 0.769873934784238 SMIM17 other 1 1 1 -0.322380824951169 0.292721548421223 0.106165830043822 -7.7917585175808 4.54517841024155 -1.71429101661308 0.0871827172477882 -17.9438230974777 9.83113557493208 -1.82520350377751 0.0686512080264283 FENDRR other 1 1 1 -1.71429101661308 -1.82520350377751 0.145898085576327 -2.40594613562081 4.64723233877341 -0.517715913522808 0.604919069963129 2.35811779171708 5.83275987950281 0.404288508430437 0.686198817559456 MIMT1 other 1 1 1 -0.517715913522808 0.404288508430437 5.33125684713875e-42 58.5413101271084 12.7551945914405 4.589605411931 5.81555476848911e-06 -43.0150785079337 15.9245491435093 -2.70118030471627 0.00717865567463986 A1BG-AS1 other 5.002851425355e-38 1 0.0509384442171961 4.589605411931 -2.70118030471627 7.83181931324069e-07 40.8496295676195 10.0306579926026 4.07247755807698 5.52947979524908e-05 -33.7248650119292 21.0012623257918 -1.60584942413254 0.109034323908461 MAN1B1-AS1 other 0.00478289205459609 1 0.465471609164067 4.07247755807698 -1.60584942413254 2.31693397464821e-20 328.712568379156 44.7480167369498 7.34585781335262 1.00715354293065e-12 123.657439868665 63.2945162377558 1.95368330811101 0.0513748386577962 FBXO17 other 1.98491733608112e-16 1 9.69687431133628e-09 7.34585781335262 1.95368330811101 0.00675798238831321 -10.0530342964645 7.32188456997814 -1.37301185239724 0.170460913131793 -23.2259246503935 9.13188408765803 -2.54338802676919 0.011325913092842 ZNF350-AS1 other 1 1 1 -1.37301185239724 -2.54338802676919 4.71560932085833e-07 67.8448633288498 19.1032641115541 3.55148015190848 0.000424609361903135 -86.4488709334904 38.871267906901 -2.22397867598609 0.0266590580555267 ZSCAN16-AS1 other 0.00292037685240756 1 1 3.55148015190848 -2.22397867598609 1.14567471775713e-17 20.2710021968035 10.472067456528 1.93572112488324 0.0535465312391582 -31.8163855814411 13.0653389220725 -2.43517491365575 0.0152836391293537 ZNF587B other 9.55263579665892e-14 1 1 1.93572112488324 -2.43517491365575 3.69959208956738e-08 1.60446889669811 6.17245970910045 0.259939954623363 0.795032234858315 -18.9714052330885 7.53159586516364 -2.51890908284632 0.0121269936039021 PLA2G4C-AS1 other 0.000244580033041299 1 1 0.259939954623363 -2.51890908284632 2.5298120967334e-18 5.41659624140838 29.7213545880707 0.182245941225789 0.855474037616902 -182.155982278774 35.7511922919922 -5.09510230570897 5.19180359660128e-07 RPARP-AS1 other 2.12656004851409e-14 0.00462330110277344 1 0.182245941225789 -5.09510230570897 0.465085481530054 -26.1291162719784 34.3888671491481 -0.759813231376702 0.447775927853838 -9.96059628195702 43.1552947979621 -0.230808208554455 0.817571821145311 ZIM2 other 1 1 1 -0.759813231376702 -0.230808208554455 3.85614961799138e-23 84.9530249517232 11.7666882537472 7.21979057486027 2.32586962662925e-12 40.9543589287534 14.7662584575356 2.77350955535071 0.0057829271772711 ZIM2-AS1 other 3.37837268032224e-19 1 2.23609105904136e-08 7.21979057486027 2.77350955535071 1.24374489759438e-08 89.527020980796 18.4839017216722 4.84351314613551 1.77389547094173e-06 130.149403524171 21.124129281798 6.16117245771248 1.64063343492613e-09 KCNQ1OT1 other 8.45995279343694e-05 1.53185943819053e-05 0.0158054086460908 4.84351314613551 6.16117245771248 3.9454031128495e-16 312.378051462143 49.828759788851 6.26903123388666 8.82980146204816e-10 163.490738127277 62.864307104928 2.60069259738108 0.00962341015551412 ZNF528-AS1 other 3.22931244786732e-12 1 8.33003469929623e-06 6.26903123388666 2.60069259738108 2.99241713255505e-43 412.427081988047 71.8507412374066 5.74005326716562 1.77732317511272e-08 -349.884083271773 98.1334667117554 -3.56539002437851 0.000403601338757248 EGLN2 other 2.81736073030058e-39 1 0.000164740085101198 5.74005326716562 -3.56539002437851 2.05299283457908e-07 48.2923033699937 31.5228085914331 1.53197971652558 0.126249368036683 -83.0717486503001 39.8298876705098 -2.08566364378192 0.0375873335269862 ARHGAP19-SLIT1 other 0.00129974976357202 1 1 1.53197971652558 -2.08566364378192 0.201970097737544 -12.7738380260734 126.077191802954 -0.101317596334455 0.919344817329488 -248.743243831491 174.273516988342 -1.4273152233918 0.154203200647628 SNHG8 other 1 1 1 -0.101317596334455 -1.4273152233918 7.80978135695926e-12 174.870494582442 31.3793307095405 5.57279236453807 4.39769227498274e-08 -43.9683146605733 61.5487297345887 -0.714365915432765 0.475383218313779 COMMD3-BMI1 other 5.89638492450424e-08 1 0.000404807573912161 5.57279236453807 -0.714365915432765 0.712483071969375 -1.36768911568439 10.4669294770449 -0.130667653649896 0.896098766301625 7.61666573206977 12.2296073566561 0.622805418844808 0.533739506436402 RMRP other 1 1 1 -0.130667653649896 0.622805418844808 5.53858678066453e-31 1.78388942300118 3.24216804246538 0.550214979493995 0.582452406308475 -26.5848809455013 4.16325965906915 -6.38559281009279 4.36190978093723e-10 MKNK1-AS1 other 5.02959065552146e-27 4.10499329484003e-06 1 0.550214979493995 -6.38559281009279 3.25590670745098e-05 -2.33066317362745 2.59001189039527 -0.89986582002593 0.368687260302698 -9.35456026332129 3.23910060595635 -2.88801164314541 0.00406940720320754 SPACA6P-AS other 0.171586283482666 1 1 -0.89986582002593 -2.88801164314541 1.39071855557269e-08 16.2872400371319 12.0857807407216 1.34763656453355 0.178478366313777 -34.8821436520475 16.0813285632238 -2.16910832428479 0.0306167051305837 LINC01480 other 9.43880683667186e-05 1 1 1.34763656453355 -2.16910832428479 7.62691984456679e-15 230.858789849441 76.7640727380683 3.00738068754076 0.00278718196405263 -388.102278928393 102.725519178317 -3.77805127715835 0.000179965123880914 BIVM-ERCC5 other 6.11755240732702e-11 1 1 3.00738068754076 -3.77805127715835 1.11649623210233e-11 78.6661244999615 52.6985101612496 1.49275803545973 0.136311115020396 -151.977490413515 65.2982405269185 -2.3274362247305 0.0204544426565887 NBPF8 other 8.41056611642689e-08 1 1 1.49275803545973 -2.3274362247305 0.343677885929047 -1.01402792833007 4.80975530185621 -0.210827342492606 0.833120499655535 -10.0383922249034 7.75638085495208 -1.29421084557682 0.196277678175165 POC1B-AS1 other 1 1 1 -0.210827342492606 -1.29421084557682 5.85403552833848e-15 36.5468460176996 11.5877997015013 3.1539072955295 0.00172213320963291 -50.8164460176986 16.1006427950658 -3.15617498409889 0.0017090988243769 HMGN3-AS1 other 4.70020512570297e-11 1 1 3.1539072955295 -3.15617498409889 4.66820374328762e-11 5.14958150957904 2.32176693265457 2.21795798585662 0.0271347082385447 -4.27653440209726 2.8768801082237 -1.48651811727314 0.137952159134377 PFN1P2 other 3.46800856088837e-07 1 1 2.21795798585662 -1.48651811727314 7.79240975487946e-10 45.0004991443243 15.5020792438583 2.90286860468429 0.003884347201413 -31.6222190530516 20.4358488526624 -1.54738955455387 0.122491542629268 CAHM other 5.57001449278784e-06 1 1 2.90286860468429 -1.54738955455387 0.233063559855585 7.74263288700795 30.6317902928201 0.25276462175385 0.80056896011578 -35.509751817332 34.6003320854782 -1.0262835550135 0.305325680210266 LINC01235 other 1 1 1 0.25276462175385 -1.0262835550135 0.0319920634638454 1.01952502592378 1.08428134835355 0.94027719601735 0.347593654885428 -4.35027862785267 2.32267450445801 -1.87296094201017 0.0617396261956969 HCG17 other 1 1 1 0.94027719601735 -1.87296094201017 5.04183090396943e-06 642.234138009564 185.420640623798 3.46366044173366 0.000585562330716429 -1048.00821377059 402.826083367937 -2.60163940976322 0.00959361565135993 TAF15 other 0.0288846492488408 1 1 3.46366044173366 -2.60163940976322 0.487927106337217 -2.13881889763804 5.09262095994204 -0.419983916820383 0.674703615133707 -7.18497637795297 6.72582266764559 -1.06826729353364 0.285989708591741 FBXW7-AS1 other 1 1 1 -0.419983916820383 -1.06826729353364 0.531223906084186 9.09214830970563 9.01730937332118 1.00829947529646 0.313868678541798 14.5672482733552 19.5898346490529 0.743612620235131 0.45751047420549 GAS2L2 other 1 1 1 1.00829947529646 0.743612620235131 1.04177524739645e-12 771.363809846905 126.755546864457 6.08544421864033 2.53769906997719e-09 -592.130804461221 297.593397718369 -1.98973098530093 0.0472419437475276 RPS10-NUDT3 other 8.0185440792105e-09 1 2.38289942670858e-05 6.08544421864033 -1.98973098530093 0.000422500615800731 37.6268629589237 53.7360087712663 0.700216927518509 0.484164447288227 -420.460014540168 116.739870281444 -3.60168307131484 0.000352461919119606 RASL10B other 1 1 1 0.700216927518509 -3.60168307131484 0.00583870532381528 23.6778499953241 10.6717468408277 2.21874172508835 0.0270185455010086 -26.537758346582 22.6077418510253 -1.17383498632697 0.241101923271593 LPP-AS2 other 1 1 1 2.21874172508835 -1.17383498632697 3.58127870172251e-42 60.2504040236612 13.0457430303537 4.61839573901429 5.09076818439527e-06 -68.0586119197339 16.8326205426366 -4.04325706430222 6.22818246865943e-05 TMEM56-RWDD3 other 3.36282070091743e-38 0.502988016168935 0.0447020354271748 4.61839573901429 -4.04325706430222 0.000810213584365457 23.8647520982495 21.2956771432279 1.12063833132625 0.263058721962176 -128.077998552006 44.8990436081289 -2.85257743282571 0.00454291125479315 TMCC1-AS1 other 1 1 1 1.12063833132625 -2.85257743282571 0.440963355637667 -44.1467774994305 51.0633430016959 -0.864549301011576 0.387761608238102 -126.052076216503 110.935041513424 -1.13626924817304 0.256468054020912 MMP28 other 1 1 1 -0.864549301011576 -1.13626924817304 0.262770775564907 34.8176117775358 28.4507669319935 1.22378464737914 0.221692890299272 84.4857324609236 61.8084393871938 1.36689638661915 0.172360544649779 CCL5 other 1 1 1 1.22378464737914 1.36689638661915 0.183920910870861 -21.2446598227383 18.3376067815059 -1.15852957672559 0.247282154759099 -54.4590689885466 29.5718707583358 -1.84158349106796 0.0662151535366534 ATP2B1-AS1 other 1 1 1 -1.15852957672559 -1.84158349106796 1.75309539265368e-77 160.284062790587 27.536200627676 5.82084888753642 1.13292944538631e-08 -253.537129558123 35.3591645268529 -7.17033710922606 3.20603844396187e-12 MROH7-TTC4 other 1.7185594134184e-73 3.07234664084866e-08 0.000105328450537565 5.82084888753642 -7.17033710922606 0.000621711038171361 6.64596631727721 5.0342658961303 1.32014606586152 0.187475734062526 -6.66255446943817 6.10302084920074 -1.0916814204085 0.275573286229148 BMS1P4 other 1 1 1 1.32014606586152 -1.0916814204085 6.61177444543609e-07 5.99405476379658 7.22132167865406 0.830049543633373 0.406962950691267 -39.157912235916 11.2364070328724 -3.48491400510489 0.000541897550618911 SNORD58B other 0.00405830715460867 1 1 0.830049543633373 -3.48491400510489 4.25093297997893e-18 82.7146664749928 57.751940383345 1.4322404741027 0.152788265322507 -359.108409954948 75.8615552622297 -4.73373382227166 2.98056333971199e-06 GTF2H5 other 3.56015637073235e-14 0.0258176396485853 1 1.4322404741027 -4.73373382227166 0.00554532989866066 38.2257722485325 13.7947884472308 2.77102997227956 0.00582636919056495 11.2569449353213 18.4601566156101 0.609796827281642 0.542313340457087 FGF14-AS2 other 1 1 1 2.77102997227956 0.609796827281642 0.00241829257222833 8.32635001114995 3.1665359957417 2.62948219200637 0.00885384277391723 -2.89883376563412 5.22388465227358 -0.554919175784723 0.579234508876039 ARF4-AS1 other 1 1 1 2.62948219200637 -0.554919175784723 0.00307286253910141 193.627946373278 87.7638127276714 2.20623899937096 0.027886800981061 -199.050366133554 163.1393759176 -1.22012460213218 0.223075666024505 CASC15 other 1 1 1 2.20623899937096 -1.22012460213218 1.03591835268786e-05 85.316165557004 352.66818230972 0.241916253964974 0.808958278012189 -3634.05753926186 827.985245907526 -4.38903658878449 1.42855240193663e-05 NUDT3 other 0.0574623910235954 0.119855546522483 1 0.241916253964974 -4.38903658878449 6.24095324067718e-45 467.833050960613 77.4902306527881 6.03731653680115 3.35564624606446e-09 -304.397497134831 102.773428095774 -2.96183072584838 0.00322530968330644 KMT2B other 5.89770081243993e-41 1 3.14726061418386e-05 6.03731653680115 -2.96183072584838 7.60687949046565e-05 611.765304589939 498.734337672045 1.2266356221741 0.220621574949039 -1223.35069143591 663.976071337325 -1.84246201669879 0.0660863809746146 CD24 other 0.382549969575518 1 1 1.2266356221741 -1.84246201669879 0.000165079061170075 -22.8065087012079 26.8780123021748 -0.848519170421041 0.396613440318295 -143.010913381181 39.3027072877547 -3.63870387691431 0.000306757564299528 FAM47E-STBD1 other 0.796176312023272 1 1 -0.848519170421041 -3.63870387691431 0.135941505909255 -1.08445371991362 31.6971314935754 -0.0342129924322465 0.9727228918506 -79.5348793087089 48.8906724720889 -1.6267904548483 0.104500774608163 MUSTN1 other 1 1 1 -0.0342129924322465 -1.6267904548483 4.9751773327749e-16 55.2741549876343 36.4867562485807 1.51491008438944 0.130516465993506 -171.383140972795 44.2327518449037 -3.87457559895272 0.00012313860765793 ZSWIM8-AS1 other 4.06621243407692e-12 0.971686753028724 1 1.51491008438944 -3.87457559895272 0.000564718981235974 13.6288619746489 18.1437067712218 0.751161939866997 0.452965137581395 -74.1355296346355 28.2161423308376 -2.62741549732021 0.00891048852111274 ZNF595 other 1 1 1 0.751161939866997 -2.62741549732021 0.0573942257365975 -45.9089789501757 20.3379243245781 -2.25730896710513 0.0244817130161235 -63.4271825926066 32.3052712044659 -1.96336945110798 0.0502369776065137 AFAP1-AS1 other 1 1 1 -2.25730896710513 -1.96336945110798 0.0880840566257635 185.278763562387 94.3928385070521 1.96284767459922 0.0502978046862866 -44.7865978957741 199.010226756356 -0.225046715567062 0.822048128857289 PCDHB16 other 1 1 1 1.96284767459922 -0.225046715567062 0.579605338993316 -3.07957651290046 3.44827474633591 -0.893077477707592 0.372319904414786 -0.726025521171308 4.87440257756245 -0.148946565167453 0.881666280128644 GAS6-AS2 other 1 1 1 -0.893077477707592 -0.148946565167453 1.15708482586304e-14 35.5984782993043 7.97998438131968 4.46097092403297 1.03847709576849e-05 -9.65083919110871 10.2769191182484 -0.939079025539089 0.348207737158927 JMJD1C-AS1 other 9.24857901312325e-11 1 0.090108657599832 4.46097092403297 -0.939079025539089 3.34457810836905e-05 95.677337288823 46.4795146107533 2.05848400290066 0.0401346423014545 -148.163638245211 71.6914944166666 -2.06668363452005 0.0393511225665095 DCP1A other 0.17609203740563 1 1 2.05848400290066 -2.06668363452005 1.48814286337753e-11 18.0549447984502 2.5852737427009 6.98376520065832 1.0785916304602e-11 -6.92831034241297 10.3035130927558 -0.67242214185025 0.501671179733995 RBAK-RBAKDN other 1.11804173325554e-07 1 1.03285934532869e-07 6.98376520065832 -0.67242214185025 8.66655469109745e-09 134.843469075455 33.0816729842517 4.07607768626593 5.43931060375588e-05 -75.6146218612345 54.4228505064807 -1.38939105830611 0.165419752381717 DGCR9 other 5.94178989621641e-05 1 0.457935559730207 4.07607768626593 -1.38939105830611 0.0075176321198767 -4.38467894239915 15.2868612447749 -0.286826633158448 0.774380701618348 -85.8884560906528 29.5979271236697 -2.90184024481793 0.00389687553239243 LINC02035 other 1 1 1 -0.286826633158448 -2.90184024481793 0.150886884221988 12.5459537856066 24.3061003982518 0.516164813772798 0.606002783894392 -38.7168273116641 28.4385318652729 -1.36142145083595 0.174088535650283 FAM95C other 1 1 1 0.516164813772798 -1.36142145083595 4.01058346346251e-11 5.60967620192212 2.1260864471731 2.63849864119161 0.00862548237720269 -7.38955066925111 2.44795223676804 -3.01866619710168 0.00268784223022547 CDC37L1-AS1 other 2.98146774673803e-07 1 1 2.63849864119161 -3.01866619710168 3.91421219540567e-13 36.0721253377632 23.9605449308266 1.5054801734227 0.132924762649683 165.593335298281 30.7932997152283 5.37757683748292 1.23351652719213e-07 ZBTB8B other 3.04095145461066e-09 0.00111719591867791 1 1.5054801734227 5.37757683748292 0.262791411372551 77.6382586663597 50.7913232214433 1.52857326295414 0.127097072917 28.0036056308078 105.879144094336 0.264486513093242 0.791530323025471 C1QTNF3-AMACR other 1 1 1 1.52857326295414 0.264486513093242 4.10215286429232e-06 13.1208308333037 5.16021142950826 2.5426924870313 0.0113473320133463 -18.5480232540552 8.70497727908087 -2.13073769860703 0.0336736252070476 TM4SF19 other 0.0236899327912882 1 1 2.5426924870313 -2.13073769860703 0.0871370857632774 -3.491038173679 4.23169963707489 -0.824973054111217 0.409836976452231 11.3081094100646 8.35918666165536 1.3527762768998 0.176826600292956 AGBL1 other 1 1 1 -0.824973054111217 1.3527762768998 0.186040472879329 4.42203164633411 3.0294077931008 1.45970168044226 0.145093851847014 -2.76740347062847 6.44426880818724 -0.429436380293848 0.667818302440515 HIST1H4K other 1 1 1 1.45970168044226 -0.429436380293848 4.0362159957249e-07 96.6731182795703 19.3599153176733 4.9934680339908 8.58593782195179e-07 -50.2064516129037 43.8017008842622 -1.14622150736942 0.252330757687176 CWC25 other 0.00251092997094046 1 0.00771704091437027 4.9934680339908 -1.14622150736942 2.03644932381144e-06 48.651160474151 14.7794265115201 3.2918165286203 0.00109395037829029 -64.1328636499467 26.2321702671811 -2.44481729863514 0.0149713339475754 SMIM11B other 0.0120496706489923 1 1 3.2918165286203 -2.44481729863514 1.35823045243581e-05 68.5359424563288 38.0700573510015 1.80025845047816 0.0725093241487432 -319.586069785104 83.3839688091638 -3.83270398793949 0.000145339243866485 EPOP other 0.0745125226206285 1 1 1.80025845047816 -3.83270398793949 2.65660959963628e-06 69.4148497348254 27.526540991022 2.52174255230491 0.0120311721828492 -220.011022468006 59.7998041093595 -3.67912614003984 0.000263171707421188 ZNHIT3 essential 0.0155889851306657 1 1 2.52174255230491 -3.67912614003984 0.0172882469255763 21.5204906515021 8.22430516421763 2.61669408196738 0.00918560489482898 -9.73934138962816 18.4537579898251 -0.527770083199214 0.597926177281713 LHX1 other 1 1 1 2.61669408196738 -0.527770083199214 0.00135569659526254 384.609294047138 462.003969152967 0.832480497412774 0.405598815506357 -1935.85770979454 796.433532849351 -2.43065821559363 0.0154784474745927 CYFIP1 other 1 1 1 0.832480497412774 -2.43065821559363 0.00225377792986796 19.9870323020974 5.84994058161222 3.41662142089469 0.000693637872829379 26.5946397465541 11.9048806541602 2.2339274553971 0.0259953454428521 HIST1H2BG other 1 1 1 3.41662142089469 2.2339274553971 2.70112199459815e-05 2.25549795589567 1.91104495927716 1.18024327211475 0.238544045635474 -5.55536493240874 2.51580538441227 -2.20818548478723 0.0277486856386584 FRMD6-AS1 other 0.143618656452784 1 1 1.18024327211475 -2.20818548478723 0.680095845464772 63.2239398136024 470.8752174517 0.134268989894521 0.893251972678966 428.765086368233 620.057590152197 0.691492360028994 0.489625056643101 RN7SL2 other 1 1 1 0.134268989894521 0.691492360028994 0.00017450203288931 13.5136331806829 4.53579039759306 2.97933369845616 0.00305359793942139 -17.7201851633815 10.5852439652804 -1.67404598528893 0.094853835601266 FAM27E3 other 0.838482268033134 1 1 2.97933369845616 -1.67404598528893 0.0557822888870768 36.7775120979216 20.8073151010453 1.76752800249918 0.0778360682142346 -27.504906750631 16.2538124812329 -1.6922126290302 0.0913166284793493 NATD1 other 1 1 1 1.76752800249918 -1.6922126290302 0.00141420255072602 126.440512889246 85.815879996584 1.47339295354519 0.141365029754263 -535.352421480588 187.960543242467 -2.84821703664684 0.00460397275136594 SOCS7 other 1 1 1 1.47339295354519 -2.84821703664684 0.155812137983735 8.45668827342365 4.72004417156016 1.7916544773835 0.0738785291671091 -2.43045797259111 10.2540205447129 -0.237024878387267 0.812748307653085 TBC1D3H other 1 1 1 1.7916544773835 -0.237024878387267 0.0154887359807876 10.7263671680452 260.373976407421 0.0411960032106324 0.967162477470473 -1228.80537721069 462.140697877454 -2.658942142197 0.00818865097631479 CBSL other 1 1 1 0.0411960032106324 -2.658942142197 0.807362957375426 4.65897399329711 11.2898956917403 0.412667585290945 0.680053489042701 14.6300487944012 22.9754232428535 0.636769501034195 0.524609938214529 HIST1H2BE other 1 1 1 0.412667585290945 0.636769501034195 0.00049854987061084 32.3841867226622 10.5650383831138 3.06522187126382 0.00231342001798863 -29.0841295677349 24.6561281698567 -1.17959029768882 0.23882152790055 ZNF658 other 1 1 1 3.06522187126382 -1.17959029768882 1.12898759775913e-58 4.79529626659693 2.95507854693599 1.62273056043434 0.10536651502899 -33.6499792072069 3.79483082060886 -8.86731999341355 1.90997429129402e-17 TMEM269 other 1.09094071571464e-54 1.86776385945642e-13 1 1.62273056043434 -8.86731999341355 0.0486054509324124 13.7852150537636 5.8536390642739 2.35498207224595 0.0189649063053863 -2.37688172043006 13.2438258727143 -0.179470928059168 0.857651126589419 TBC1D3D other 1 1 1 2.35498207224595 -0.179470928059168 0.00172421595208126 45.3343825019176 62.31767943019 0.727472250514438 0.467326266243824 -247.10422017323 102.527982472088 -2.41011491902223 0.0163596834552237 PI4KAP1 other 1 1 1 0.727472250514438 -2.41011491902223 0.1248930783623 11.6405913978496 5.84405348834999 1.99186941410699 0.0470072709788613 0.0844086021505991 13.2221385604232 0.00638388425328204 0.994909345097357 TBC1D3 other 1 1 1 1.99186941410699 0.00638388425328204 1.13757289751117e-05 28.0377570874122 10.0822966559326 2.78088991469165 0.00565644110896999 97.8868560717953 20.5179072734506 4.77080117222566 2.5088463371876e-06 HIST1H3E other 0.0628509025874919 0.0218018746701602 1 2.78088991469165 4.77080117222566 0.0244147738574207 41.9281426553706 87.5397954345031 0.4789609393906 0.632205984237667 -416.899139702103 184.56182497705 -2.25885900160526 0.0243842808365772 NPHP3-ACAD11 other 1 1 1 0.4789609393906 -2.25885900160526 1.64791445911356e-13 19.7990546452407 5.10882626513563 3.87546054958967 0.000122706784591163 -6.15473359816673 5.92940339414227 -1.03800217138997 0.299841728879265 PANO1 other 1.29196493594503e-09 1 1 3.87546054958967 -1.03800217138997 0.133568477351727 8.28874484384202 4.4669692068963 1.85556346147305 0.0641873629271278 -2.62600667845214 9.70422995108846 -0.270604333541952 0.786822830081528 TBC1D3I other 1 1 1 1.85556346147305 -0.270604333541952 4.46406270915932e-06 6.55300263147542 9.36392578228289 0.699813602097755 0.484415224202273 -56.0280690729614 15.2329831416636 -3.6780759587214 0.000264224562041089 ZNF280B other 0.0257174652674669 1 1 0.699813602097755 -3.6780759587214 0.000297889535548365 339.990215788771 253.607704883341 1.3406146944359 0.180742068587615 -1869.88557163919 555.471108403774 -3.36630572382526 0.000829152674658341 MLLT6 other 1 1 1 1.3406146944359 -3.36630572382526 0.000435313466306011 246.736155913981 88.4409856476658 2.78983950831277 0.00550407378916108 -422.348655913981 200.097238840297 -2.11071706117378 0.0353641520681756 SYNRG other 1 1 1 2.78983950831277 -2.11071706117378 8.66978637513587e-17 68.6724598253859 24.6935335849804 2.78098958940228 0.00565310727888809 -45.5813503583427 30.6404694589231 -1.48761919002088 0.137570892635109 LENG9 other 7.16124354586223e-13 1 1 2.78098958940228 -1.48761919002088 0.817095382166913 132.258102533883 225.692148887726 0.586011091593961 0.558169905381432 190.924414124472 490.303024157969 0.389400849510075 0.697168899740033 CCL4 other 1 1 1 0.586011091593961 0.389400849510075 0.685929229048172 -9.91131408367692 15.2970320533648 -0.647923992647762 0.51737359726889 -24.1338485713854 33.2319095430176 -0.726225152368836 0.468088649216071 CCL18 other 1 1 1 -0.647923992647762 -0.726225152368836 8.74059296635801e-08 2713.42585386821 1165.45022526117 2.32822114154223 0.0203558525502779 -1736.77906303722 1602.89142540647 -1.08352882516469 0.279171220683158 FCGBP other 0.000566128206431009 1 1 2.32822114154223 -1.08352882516469 9.98038830203707e-06 306.028260402378 84.871497473719 3.60578367899237 0.00034701653102976 -447.11166123886 190.435306489877 -2.34784016409598 0.0193266932476533 AATF essential 0.0555009393476282 1 1 3.60578367899237 -2.34784016409598 0.0187415584621962 -2.57717557502616 3.58740994227633 -0.718394500905815 0.472897108103574 -9.86554319280174 4.71453849106051 -2.09257877764883 0.0369617146227983 HNRNPCL2 other 1 1 1 -0.718394500905815 -2.09257877764883 0.156527354522999 -3.02151617924639 2.89778679767634 -1.04269788987556 0.297663398922176 -9.10242068296504 4.72777057892238 -1.92530930403983 0.0548378372910789 RIMBP3 other 1 1 1 -1.04269788987556 -1.92530930403983 0.726816856966053 -159.090649153382 199.306594701602 -0.798220698073584 0.425175985044301 -105.763659920479 436.536638829671 -0.242278999087052 0.808677646140544 ARHGAP23 other 1 1 1 -0.798220698073584 -0.242278999087052 2.69901759108365e-05 -0.77616043421569 35.0857790195895 -0.0221217956649141 0.982361038017336 -230.053374687201 60.4832269916957 -3.80358962524912 0.000163210153394148 TUBGCP5 essential 0.143560745669739 1 1 -0.0221217956649141 -3.80358962524912 0.000317024148692909 163.125211674471 57.7375317868861 2.82528896934111 0.00498709651208836 -162.586856713362 102.478994260015 -1.58653837195981 0.113495159608867 U2AF1L5 other 1 1 1 2.82528896934111 -1.58653837195981 0.19999265901061 6.37389510901589 3.80465361597183 1.6752891990636 0.094591216582853 -1.62780472326728 8.26538797640026 -0.196942324778349 0.84396402449334 TBC1D3F other 1 1 1 1.6752891990636 -0.196942324778349 0.0880297340290565 67.4971774193544 34.5794025961654 1.95194747022146 0.0515827471313597 -44.1180107526889 78.2357063251739 -0.563911452007854 0.573103668920714 DUSP14 other 1 1 1 1.95194747022146 -0.563911452007854 0.198357527246477 -162.001459744732 309.923286125788 -0.52271470714524 0.601438919471529 325.464781319011 408.112975168242 0.797486973269695 0.425603357956968 RN7SL1 other 1 1 1 -0.52271470714524 0.797486973269695 2.61834212664871e-07 23.2062447155453 4.67747160491861 4.96127965611651 1.00646249400653e-06 43.6764907194912 9.95009137871969 4.38955674446391 1.42745497788759e-05 HIST1H4I other 0.00164746086608737 0.119777747194548 0.00902293625876856 4.96127965611651 4.38955674446391 0.0599813649389247 10.587223241169 5.49381470166714 1.92711691531137 0.0546344820656128 -7.65993953089502 12.821702412976 -0.59741984989005 0.550546768067661 ANKRD20A3 other 1 1 1 1.92711691531137 -0.59741984989005 0.0303623657903407 0.498408545149709 7.36579039150961 0.0676653174551659 0.946082935810043 14.5869919804268 5.50593849108586 2.64931982150603 0.00835704953519243 PIK3R6 other 1 1 1 0.0676653174551659 2.64931982150603 1.67254933314542e-06 80.4053763440869 27.1701044686794 2.95933261636057 0.0032506568150579 -216.972043010753 61.4722104618319 -3.5295955909292 0.000460357950923451 TADA2A essential 0.00996504892688041 1 1 2.95933261636057 -3.5295955909292 0.000106992990457885 604.580976634041 308.014427101127 1.96283330727085 0.0502994804604993 -2169.4734843408 674.636897585265 -3.21576464629494 0.00139755556551852 PIP4K2B other 0.528224393890579 1 1 1.96283330727085 -3.21576464629494 0.000234637452758123 -1961.62788200712 2832.86023039303 -0.692454876863078 0.489019499798239 -24125.7399926024 5972.57340425738 -4.0394212610941 6.32952138315687e-05 PCDHGB5 other 1 0.51079237562076 1 -0.692454876863078 -4.0394212610941 0.52931808347182 56.7217072569022 235.175634307679 0.24118870742661 0.809523559822283 -308.504070771503 405.411584699475 -0.760965109075983 0.447094030262201 HERC2P2 other 1 1 1 0.24118870742661 -0.760965109075983 0.419507712381166 59.663166040239 56.0462534882935 1.06453442160413 0.287677212020403 21.8010833517586 64.9227876400717 0.335800173471024 0.737183461000231 DACH1 other 1 1 1 1.06453442160413 0.335800173471024 0.000313976388532002 17.6187058787576 4.54903997119744 3.87306024794499 0.000124000157439588 25.581824849491 9.25749196809527 2.76336452007254 0.00596366222102985 HIST1H2AE other 1 1 1 3.87306024794499 2.76336452007254 0.00564637188123174 47.7748968768412 16.4343300771377 2.90701821446938 0.00383416531266716 -22.3150053639151 35.7026231374994 -0.62502425320332 0.532280616140136 PIGW other 1 1 1 2.90701821446938 -0.62502425320332 0.781414371294419 -14.9637743091479 37.5091828813042 -0.398936291320981 0.690134571084535 7.5215154299767 52.2883845686025 0.143846773849141 0.885687624602748 RPPH1 other 1 1 1 -0.398936291320981 0.143846773849141 1.04537373748119e-07 8.47401651287031 3.22908724975075 2.62427610573991 0.00898744950178998 -9.77918083211916 4.7201760743035 -2.07178306024573 0.0388717866059565 GTSE1-AS1 other 0.000672907074816642 1 1 2.62427610573991 -2.07178306024573 0.000101548641857971 472.568109726133 140.981910208741 3.35197692403542 0.00087213099600072 -553.672318277262 308.789427216156 -1.79304169598295 0.0736576704958082 PCGF2 other 0.503173520406248 1 1 3.35197692403542 -1.79304169598295 0.267440811438169 -364.024884957335 227.205325198817 -1.60218465231303 0.109837331052074 -339.886286467409 497.642584958061 -0.682992767783435 0.494973330978407 SRCIN1 other 1 1 1 -1.60218465231303 -0.682992767783435 0.234099070314404 -9.00612071661492 22.998751753748 -0.391591718239545 0.695550784233907 -85.9504869767232 50.3736356686568 -1.70625935245335 0.0886702799116807 GPR179 other 1 1 1 -0.391591718239545 -1.70625935245335 2.46390287321218e-15 2393.85601156873 2176.41499669545 1.09990788301102 0.27197641558726 -13633.5887360556 2914.62083024675 -4.67765432627523 3.87196108458768e-06 MARCKS other 1.99157269241741e-11 0.0333995363156533 1 1.09990788301102 -4.67765432627523 0.0271408097722935 15.2231614960473 7.62772172044097 1.99576781298298 0.0465808497021815 -15.3929283199362 15.0732347910112 -1.02120935110197 0.307721554580559 ZNF670 other 1 1 1 1.99576781298298 -1.02120935110197 0.0862908091571559 0.601981301998518 1.24044296688496 0.485295429188684 0.627709994747483 -5.57185631077035 2.96050940152527 -1.88205999545203 0.0604921465886498 PKD1L3 other 1 1 1 0.485295429188684 -1.88205999545203 0.846662531309934 29.6670899004409 53.8332880595501 0.551091916726754 0.581852304354672 0.276509283719522 171.132005641871 0.00161576604377661 0.998711543095765 GPIHBP1 other 1 1 1 0.551091916726754 0.00161576604377661 0.0651283920103067 470.588685916317 237.777558575437 1.97911312041258 0.0484290840206808 891.148202710663 516.5578715121 1.72516624342988 0.0852028953902942 CCL3 other 1 1 1 1.97911312041258 1.72516624342988 0.586327363534297 3.79592966740908 7.74542429777205 0.490086730109926 0.62432542149047 -5.10255810805821 9.08694590022099 -0.561526189776712 0.574734855132026 PGM5P2 other 1 1 1 0.490086730109926 -0.561526189776712 5.51141479605677e-06 605.319706920428 121.959023395064 4.96330398579534 9.94985067743019e-07 207.558526560334 267.124036851564 0.7770117920001 0.437572206406584 PSMB3 essential 0.0314481328262999 1 0.0089230260875194 4.96330398579534 0.7770117920001 0.000155386259066205 281.429879819506 77.6620807663083 3.62377465350628 0.00032447442864529 -200.332707858643 170.101464795988 -1.17772476620888 0.239547328184536 CISD3 other 0.752380266398563 1 1 3.62377465350628 -1.17772476620888 0.0003481809648042 10.4003061814734 3.35998237341938 3.09534545887786 0.00209192067463684 6.3177111195195 2.53220433549667 2.49494522655903 0.0129649191441991 SNORA67 other 1 1 1 3.09534545887786 2.49494522655903 1.57136330932756e-08 189.393279569894 36.180184311252 5.23472401192253 2.57168525191233e-07 -154.668279569893 81.8574660650635 -1.88948286582628 0.0594888566613985 DDX52 essential 0.000106334155142196 1 0.00233714755693793 5.23472401192253 -1.88948286582628 6.92999064745292e-32 119.431948117947 38.5304100028909 3.09968017752695 0.00206278665804717 -147.589240133516 48.1304274626701 -3.06644357663321 0.00230097618209198 ZNF8 other 6.31530047702384e-28 1 1 3.09968017752695 -3.06644357663321 1.34378494742158e-10 66.5439812145554 20.0627841361719 3.31678698045607 0.000986631391782085 -31.0710599834363 24.0818848237164 -1.29022542092871 0.197654687616739 TSC22D1-AS1 other 9.85666258933728e-07 1 1 3.31678698045607 -1.29022542092871 0.0138037868862415 53.1815096404086 19.7190921206524 2.69695528146095 0.0072752506752302 53.8609848504222 23.13070042059 2.32854967082956 0.0203500489494665 GLIDR other 1 1 1 2.69695528146095 2.32854967082956 0.299625224964499 -12.9026164079826 15.0936501293989 -0.854837385083636 0.393109576620811 -36.3769844789362 23.4760460045003 -1.54953625802074 0.121976734581113 SSTR3 other 1 1 1 -0.854837385083636 -1.54953625802074 0.00625733572448815 108.22775486152 35.7297709770734 3.02906377236412 0.00259822100874684 -17.6654427874224 77.6208425896356 -0.227586331171587 0.820074043006891 MYO19 other 1 1 1 3.02906377236412 -0.227586331171587 1.06709591207337e-34 2.85347996231734 2.04746323873962 1.39366602941985 0.164125195672193 -16.0817324918247 2.62901145398168 -6.11702640833636 2.11517207054229e-09 SNORA61 other 9.817282391075e-31 1.97176340415952e-05 1 1.39366602941985 -6.11702640833636 0.136651583315477 8.6822580645163 4.66307923390892 1.86191519144276 0.0632860808269303 -2.99892473118276 10.5501908686985 -0.284253125702237 0.776351044437868 TBC1D3C other 1 1 1 1.86191519144276 -0.284253125702237 4.61601079403641e-06 121.037713612255 43.69118504247 2.77030054219406 0.00583865441060773 -316.852983394528 94.9165500924233 -3.33822692761165 0.0009151449589298 GGNBP2 other 0.0265466780765034 1 1 2.77030054219406 -3.33822692761165 8.12504464466429e-22 246.447407157185 29.8757004441542 8.24909218841117 1.914961692823e-15 144.546011845795 38.2545035745152 3.77853581511616 0.000179731554575741 ZNF229 other 7.054976264962e-18 1 1.85808733054616e-11 8.24909218841117 3.77853581511616 0.646075168582038 11.1493812610488 17.0401714816885 0.65429982750056 0.513262058415037 -17.6464424399015 37.0187782376007 -0.476688947610314 0.633821359041626 DHRS11 other 1 1 1 0.65429982750056 -0.476688947610314 0.0754405427370154 94.6506720430061 226.202243713476 0.418433833763812 0.675835510552287 -1067.77983870969 511.781320109486 -2.0863986174432 0.0375217376093928 ACACA other 1 1 1 0.418433833763812 -2.0863986174432 0.877816777561043 -1.17459107269851 2.35244271658044 -0.49930698181077 0.617814409973078 -0.807789416803028 3.87034959930337 -0.208712261276972 0.834770114926227 TMEM191B other 1 1 1 -0.49930698181077 -0.208712261276972 0.0681446662498071 18.9779569892474 8.78398220023295 2.16051860723763 0.0312753960135158 -6.79462365591398 19.8737109431493 -0.34189003127552 0.732598004478988 TBC1D3E other 1 1 1 2.16051860723763 -0.34189003127552 0.00683719197132697 11.6163148236931 11.1009556639118 1.0464247561547 0.295942088501506 -66.70774991321 24.9084080888546 -2.67812176816947 0.00768203677915002 MRM1 other 1 1 1 1.0464247561547 -2.67812176816947 0.0543940975573275 7.62407404629397 7.72518277729906 0.986911800805257 0.324233235563527 -21.1711765500069 15.1458521357202 -1.39782010020264 0.162877845119047 GOLGA6L10 other 1 1 1 0.986911800805257 -1.39782010020264 0.0385332982954406 -1160.15921198244 720.684241855995 -1.60980238584746 0.108183472023536 -193.692941162268 947.685741721789 -0.204385201375258 0.838150332433542 MIR6723 other 1 1 1 -1.60980238584746 -0.204385201375258 0.000543370744596013 87.1999285171777 45.3836069559431 1.9213970498605 0.0553317893022883 -278.148326855202 99.4026678754701 -2.79819780293685 0.00536610928418487 MRPL45 essential 1 1 1 1.9213970498605 -2.79819780293685 0.165462007548138 5.46511627906981 3.30174026262989 1.65522295648924 0.098595572398122 1.01677740863794 5.47520393215524 0.185705851551304 0.85276140797535 CEP83-AS1 other 1 1 1 1.65522295648924 0.185705851551304 2.17660691581468e-05 3.46732937325773 41.7603068627618 0.0830293078221987 0.933866428741618 -353.767022265327 84.4871410626897 -4.18722917849511 3.41955853645564e-05 HEIH other 0.116774961033458 0.281499291365762 1 0.0830293078221987 -4.18722917849511 0.719497763291485 5.31092074243782 6.55662908097515 0.810007806884806 0.418470778917592 3.08964130798973 11.637434666144 0.26549161362669 0.790782734627931 LINC01670 other 1 1 1 0.810007806884806 0.26549161362669 0.0262326327533529 -16.627359744749 17.4614866854956 -0.952230474084465 0.341510121497756 -78.8875159182193 30.0965741518122 -2.62114603211307 0.00907120124872206 PWAR5 other 1 1 1 -0.952230474084465 -2.62114603211307 0.0710003860601164 1.34134724298861 3.20749180164453 0.418191947459033 0.676011737373197 -5.47186353133069 2.39760455183106 -2.28222103063318 0.0229550208743823 C17orf100 other 1 1 1 0.418191947459033 -2.28222103063318 0.00884695078292078 2.21883833017012 4.32189761220155 0.513394469111417 0.607934275443454 -8.66538710347939 5.67714041068445 -1.52636476758106 0.127640803473001 AGPAT4-IT1 other 1 1 1 0.513394469111417 -1.52636476758106 0.278898098268109 -2.81675692077878 16.0116903309681 -0.175918773255995 0.860439245591383 -54.7072265533822 35.3902254285656 -1.54582871091928 0.122869782161705 MIR3911 other 1 1 1 -0.175918773255995 -1.54582871091928 0.32411710988741 4.24773796597907 3.14694866837709 1.34979575887702 0.177780272091782 -3.23105320304014 7.30717679713526 -0.442175315137696 0.658581096601333 MAPT-IT1 other 1 1 1 1.34979575887702 -0.442175315137696 0.540482481971224 -4.09508556014505 4.99693406102835 -0.819519631464237 0.412935712824031 -10.1698980021916 9.51007305562567 -1.06938169062493 0.285486686676435 GABARAPL3 other 1 1 1 -0.819519631464237 -1.06938169062493 0.0439204081589652 -9.71786616955824 19.0744876363934 -0.509469316020679 0.610679881943447 -87.0571655668532 35.123363061304 -2.47861132816081 0.0135651256436781 THRIL other 1 1 1 -0.509469316020679 -2.47861132816081 4.19213834835662e-19 -132.530603929043 60.1937589838437 -2.20173330535172 0.0282048111510121 -537.084844968869 77.666615205626 -6.91526009659249 1.66084609471353e-11 CCDC163 other 3.55325646406707e-15 1.58228807443358e-07 1 -2.20173330535172 -6.91526009659249 0.000837820661937057 3.552343189321 3.68517033309241 0.963956308185096 0.335600942612267 -15.3779209128752 6.17112062575692 -2.49191708369645 0.0130752270607701 EIF1B-AS1 other 1 1 1 0.963956308185096 -2.49191708369645 0.029705473027034 7.17128161556078 15.3337224191918 0.467680411808236 0.64024575439968 -67.2106894860082 30.3636140471851 -2.21352732851771 0.027375896585196 JAKMIP2-AS1 other 1 1 1 0.467680411808236 -2.21352732851771 8.71517744188433e-09 137.900722406802 44.4634327008264 3.101441207535 0.00205111540735594 -119.797234877173 55.8643204152085 -2.14443197351703 0.0325517410078408 LINC00294 other 5.97425413641171e-05 1 1 3.101441207535 -2.14443197351703 1.0334971856767e-12 111.307249645759 40.1513747476627 2.77219025115046 0.00580710943742002 -331.977306099369 78.3291134864411 -4.23823647840511 2.75248732579616e-05 LINC00836 other 7.95689483252488e-09 0.227961000322438 1 2.77219025115046 -4.23823647840511 1.19553606499391e-08 70.862835009422 57.2640365798338 1.23747537270848 0.216576670931216 -366.565067836205 89.0232317905593 -4.11763379584562 4.57984905991425e-05 CTBP1-AS other 8.13442738621855e-05 0.3738530787608 1 1.23747537270848 -4.11763379584562 3.83109271206548e-06 5.69900368204451 5.988293798643 0.951690727555145 0.341782334905316 -17.7279456356942 7.21028461659513 -2.45870261416474 0.0143325852748536 N4BP2L2-IT2 other 0.0221781957101471 1 1 0.951690727555145 -2.45870261416474 0.780515618978313 -2.97161028457579 5.43240552262616 -0.547015548121165 0.584647269933118 -6.3796209674982 9.42487957415906 -0.676891510103717 0.498832930798552 NPTN-IT1 other 1 1 1 -0.547015548121165 -0.676891510103717 1.04213540877275e-52 10.7406814070317 2.97110626052927 3.61504452052763 0.000335192650761371 -24.094127308044 3.81541317081094 -6.31494578159225 6.64197895561847e-10 SLFNL1-AS1 other 9.99616284094822e-49 6.23681823932575e-06 1 3.61504452052763 -6.31494578159225 0.339291105023857 2.84756175839493 2.07612741079871 1.37157370187576 0.170903212787083 1.27098501659727 3.14220373023236 0.404488418229737 0.686052400969464 RASSF1-AS1 other 1 1 1 1.37157370187576 0.404488418229737 8.39114484118596e-07 -2.32596157923734 20.1452089388667 -0.115459789287655 0.90813360442921 232.84363117199 47.2964010188404 4.92307292217091 1.20887187076218e-06 PANDAR other 0.00511020720828225 0.0106332369752241 1 -0.115459789287655 4.92307292217091 1.73214122326251e-05 270.166494357481 74.7343281459035 3.61502539810134 0.000335634370524598 -69.8258609392065 88.0735380125142 -0.792813170844631 0.428320858538123 EBLN3P other 0.0940206255986892 1 1 3.61502539810134 -0.792813170844631 0.0668631980882533 1.07677064220233 24.0223753125115 0.0448236541222265 0.964268486916616 -67.8914431591533 36.7442983812927 -1.84767286762831 0.0653299562943548 RBM5-AS1 other 1 1 1 0.0448236541222265 -1.84767286762831 0.311070631565584 4.03801620995746 2.79872515914429 1.44280555622406 0.149918987199258 0.442159924213104 4.96606938313263 0.0890361954496469 0.929101187845066 LINC02246 other 1 1 1 1.44280555622406 0.0890361954496469 4.86710853081243e-26 -57.8821652035495 89.5231513985925 -0.646560853804567 0.518254849471399 -772.857381519016 114.956448860401 -6.723045024273 5.56578953110101e-11 ADORA3 other 4.3307531707169e-22 5.27692505443687e-07 1 -0.646560853804567 -6.723045024273 2.6366441852809e-12 21.8917613636343 35.3568364849806 0.619166292576368 0.536129458581953 -303.99041785038 54.0258447265578 -5.62675918144313 3.28518344077137e-08 PCBP2-OT1 other 2.01307783546197e-08 0.000301152766015512 1 0.619166292576368 -5.62675918144313 1.74069431491042e-05 19.0439066859257 11.522664468121 1.65273463777525 0.0991031015125894 -36.7877916064818 15.9275062619931 -2.30970190821814 0.0213699617366426 GTF2IP12 other 0.0944326665838902 1 1 1.65273463777525 -2.30970190821814 0.00574095087384581 -70.0109052899239 143.723294520226 -0.487122880975089 0.626416622050681 -1027.02987101153 326.684938563045 -3.1437931467824 0.00178192487865028 IQCJ-SCHIP1 other 1 1 1 -0.487122880975089 -3.1437931467824 0.218873919086706 1.79533910965043 1.48811181493684 1.20645444221987 0.228296525098558 -3.68897520167315 3.48438052266664 -1.05871766234359 0.290314568124337 ARL17A other 1 1 1 1.20645444221987 -1.05871766234359 4.46365275574608e-07 13.3895389507156 3.43006251607291 3.90358452301485 0.000109742266856679 -11.5712468771291 6.81300141736141 -1.6984066446313 0.0901428503721467 TXNRD3NB other 0.00277103563076717 1 0.910312103576156 3.90358452301485 -1.6984066446313 0.0253389416880743 0.886493303478725 1.48775442904328 0.595859965981616 0.551577969669852 20.5391105539592 7.56286111986923 2.71578576261286 0.00687464181178983 MIR1244-4 other 1 1 1 0.595859965981616 2.71578576261286 6.29186830290243e-06 0.142306288431124 1.58548584747583 0.0897556346262455 0.928522620195857 -10.5009717945597 2.58077869338648 -4.06891602967336 5.60717409649497e-05 MIR1279 other 0.0356874770140626 0.454237173557058 1 0.0897556346262455 -4.06891602967336 0.697655985635101 -2.97456492637208 11.5716426545805 -0.257056410672571 0.797256212706501 -14.7723717837858 18.4268242462132 -0.801677575386958 0.423175188950657 LINC02009 other 1 1 1 -0.257056410672571 -0.801677575386958 0.000284687888703784 -48.8198923502926 60.3675635238034 -0.808710663484746 0.419120639286248 147.215217172777 78.6391790148373 1.87203400413172 0.0618680575114037 WDFY4 other 1 1 1 -0.808710663484746 1.87203400413172