model_p beta_cntot stde_cntot t_val_cntot pval_cntot beta_loh stde_loh tval_loh pval_loh gene class fdr_model fdr_loh fdr_cntot ass_coeff_CN ass_coeff_LOH 2.42227825453512e-15 156.044083543336 19.9939573759852 7.80456217890917 8.55991025877403e-14 -163.527537312851 92.3016725560527 -1.77166385813372 0.0774020101494395 DPM1 other 3.34831523124389e-11 1 1.21927361725977e-09 7.80456217890917 -1.77166385813372 0.0272831267433274 43.5277435183594 16.2873736310333 2.67248388257168 0.00791491997016637 15.0720171798652 51.5986454450392 0.292101024161949 0.770398667156379 SCYL3 other 1 1 1 2.67248388257168 0.292101024161949 0.263529258960439 25.7388239271556 20.2499598008771 1.27105555666539 0.204632056400779 63.5017942911327 64.1521782278575 0.989861857310366 0.322989518221338 C1orf112 other 1 1 1 1.27105555666539 0.989861857310366 0.755053061422312 -13.1608665965141 19.9472014086231 -0.65978511606268 0.509866311807312 7.60278663006749 39.9737781146901 0.1901943471106 0.849277435963297 FGR other 1 1 1 -0.65978511606268 0.1901943471106 0.172330861988756 31.7528359932228 124.827538676212 0.254373644870031 0.799372358404211 -797.833658480119 428.499931690191 -1.86192248697243 0.0635421471152718 CFH other 1 1 1 0.254373644870031 -1.86192248697243 0.260533976507933 32.6692014022099 51.2078056519817 0.637973078249754 0.523948889051093 -149.114417606295 112.501247195919 -1.32544679568409 0.185971465750322 FUCA2 other 1 1 1 0.637973078249754 -1.32544679568409 0.000102811011529386 1083.65679411008 270.942608681266 3.99958057311275 7.90190711717623e-05 -369.254670353513 733.198690266567 -0.503621562961691 0.614877126473018 GCLC other 0.884277510164248 1 0.827645751453039 3.99958057311275 -0.503621562961691 4.88997443819169e-09 113.446836777823 21.0383599483223 5.39238025475792 1.3586762535797e-07 -90.4400525587162 57.8993547763084 -1.56202176877665 0.119277455259585 NFYA other 5.76038988818981e-05 1 0.00168299227530917 5.39238025475792 -1.56202176877665 0.15323415681156 -6.01236073769296 25.7170181227944 -0.233789186171777 0.815298606265744 -96.1853318048676 50.1021363640399 -1.91978503882528 0.0557767074314167 STPG1 other 1 1 1 -0.233789186171777 -1.91978503882528 0.00153591634448396 -16.6844275320615 50.0997656693669 -0.333024063269483 0.73933488155943 -349.052251038 97.6048342536345 -3.57617789843235 0.000402669949751354 NIPAL3 other 1 1 1 -0.333024063269483 -3.57617789843235 0.252920350989689 5.5439984956783 16.9139440893144 0.32777680157881 0.743295445098668 77.6055670946195 46.9326314064417 1.65355243822889 0.099202174552313 ENPP4 other 1 1 1 0.32777680157881 1.65355243822889 2.05409795000998e-11 -44.0969254858818 162.236717908328 -0.271806074817163 0.785948067814399 -1458.08375510632 230.873344605334 -6.3155136319389 9.09335233042654e-10 SEMA3F other 2.62267226257274e-07 1.38819116676292e-05 1 -0.271806074817163 -6.3155136319389 0.435324193410231 51.7848613547531 44.4802057104026 1.16422261380509 0.245214812814956 -4.44374869710693 114.660603042494 -0.0387556717755972 0.969109737383014 CFTR other 1 1 1 1.16422261380509 -0.0387556717755972 1.99133914502959e-14 273.663138795049 34.755981892082 7.87384282926543 5.82997269309578e-14 -150.914446671745 150.062414966836 -1.00567784881442 0.315354896230804 ANKIB1 other 2.71041171029977e-10 1 8.31995403031699e-10 7.87384282926543 -1.00567784881442 6.3559879660275e-09 476.427813577205 76.021872487716 6.26698340867871 1.22191473702542e-09 164.452272162233 329.381059196014 0.499276651072905 0.617936369772794 CYP51A1 other 7.44603990220122e-05 1 1.62282496224346e-05 6.26698340867871 0.499276651072905 2.06426371050121e-11 147.696984582574 20.4979058860992 7.20546700737544 4.39927301309807e-12 40.1070207275273 88.6573325830757 0.452382443267683 0.651308876349485 KRIT1 other 2.6350326264548e-07 1 6.11938876121941e-08 7.20546700737544 0.452382443267683 2.28419806049968e-17 40.0206914378886 4.35153598542525 9.19691152088164 5.79533644500313e-18 -2.03608143218843 21.2732471737133 -0.0957108905641992 0.923812635873254 RAD52 other 3.2351097130857e-13 1 8.51045156948709e-14 9.19691152088164 -0.0957108905641992 0.0390363834980727 68.3515249467799 54.3867228361194 1.25676858950924 0.209765626699927 -392.638207618719 215.323185009864 -1.82348318691614 0.0691747964655584 BAD other 1 1 1 1.25676858950924 -1.82348318691614 1.85201839969389e-10 -239.511502251329 205.141080289652 -1.16754529084641 0.243864903682594 -2427.67341593949 385.191520808529 -6.30251001071811 9.76355291964504e-10 LAP3 other 2.29946604505993e-06 1.49001581106703e-05 1 -1.16754529084641 -6.30251001071811 0.0805142795950897 28.3266596338721 49.097227736746 0.576950287005136 0.564378685431357 -134.271287933291 92.0108578219899 -1.45929829491494 0.14546394238569 HS3ST1 other 1 1 1 0.576950287005136 -1.45929829491494 0.551158760180894 -13.2539744485457 16.2437006274085 -0.815945501124412 0.415138246168743 -37.5748496553349 36.091779753696 -1.04109162562112 0.298618952468882 AOC1 other 1 1 1 -0.815945501124412 -1.04109162562112 0.279161038105454 5.65137127197725 3.60861012544204 1.56607975800239 0.118324480999538 9.08591340796801 9.42373829411092 0.964151711815467 0.335702478858623 WNT16 other 1 1 1 1.56607975800239 0.964151711815467 0.00470799024315139 13.0591275258396 4.06437072076285 3.21307489474988 0.00144736923728199 -2.23912782586523 16.2737977109684 -0.137590983102615 0.890650486294062 HECW1 other 1 1 1 3.21307489474988 -0.137590983102615 7.84305907526645e-12 288.864534362985 38.9403759895076 7.41812391438692 1.09671873724977e-12 123.097300987417 177.432731269526 0.69376884471461 0.488335236040586 MAD1L1 other 1.01136246775561e-07 1 1.5390254039826e-08 7.41812391438692 0.69376884471461 9.3618780547527e-05 446.458138738033 179.323892791361 2.48967458707511 0.0132966007727833 -1491.28677127485 439.575947659883 -3.39255771207189 0.000779950256884725 LASP1 other 0.809147120272276 1 1 2.48967458707511 -3.39255771207189 0.00218805540576532 43.8193231752072 15.822932451354 2.76935538402412 0.00594551362640839 -73.6214332176259 37.6286412114155 -1.95652648746963 0.0512753501099782 SNX11 other 1 1 1 2.76935538402412 -1.95652648746963 0.135472370377184 -53.320714812036 30.5213095562823 -1.74699957463197 0.0815967699852538 -117.862288251609 67.9398961041914 -1.73480230336027 0.0837386885630724 TMEM176A other 1 1 1 -1.74699957463197 -1.73480230336027 1.78319551788143e-44 874.459546941883 53.2389039346966 16.4251981598739 2.3112703487946e-44 -230.511101191527 276.613188223509 -0.833333734634772 0.405280044409649 M6PR other 2.72918074011753e-40 1 3.53855490400453e-40 16.4251981598739 -0.833333734634772 0.0759313930919456 72.6978255746363 75.6532602785069 0.960934470067904 0.337310637638931 664.346021147228 312.910992189367 2.12311499988847 0.034511467468736 CYP26B1 other 1 1 1 0.960934470067904 2.12311499988847 0.085591313428655 -28.5642139179406 13.1914388018876 -2.16535999953646 0.0311080721375523 -51.5198531695373 61.4060299900692 -0.839003159427002 0.402101772547918 ICA1 other 1 1 1 -2.16535999953646 -0.839003159427002 0.0427081934934721 54.3129257629273 31.6912213203136 1.71381611374231 0.0875369792527479 -72.9748733226526 80.9123026202469 -0.901900835342089 0.367792140129315 DBNDD1 other 1 1 1 1.71381611374231 -0.901900835342089 1.59232126133303e-15 134.408839670846 17.8657950820597 7.52324982199173 5.52347212028305e-13 -79.240767057219 43.4794887859577 -1.8224861715212 0.0693202613396292 ALS2 other 2.20695726820759e-11 1 7.77428700929839e-09 7.52324982199173 -1.8224861715212 6.87912706504974e-05 6.68454754557323 21.6260398672201 0.30909716187592 0.757451315000153 -220.713748969449 53.1602359290972 -4.15185796511188 4.24680807580031e-05 CASP10 other 0.603918565040717 0.614130915841482 1 0.30909716187592 -4.15185796511188 4.55494613706978e-07 207.104441013997 90.7809004221599 2.28136579446663 0.023191775418948 -942.351775036841 224.121670040414 -4.20464373153616 3.40871423902779e-05 CFLAR other 0.00482833746753303 0.494604436082932 1 2.28136579446663 -4.20464373153616 0.321354727455563 -6.74247728506182 37.4351513693837 -0.180110859404088 0.857180618903354 -180.884332969957 120.004530618597 -1.50731253259805 0.132726457308146 TFPI other 1 1 1 -0.180110859404088 -1.50731253259805 3.87695281081232e-06 40.5417789311138 8.1701464670105 4.96218508380649 1.1362415561426e-06 -8.08067035258308 27.9913505351643 -0.288684547122215 0.773010287837353 NDUFAF7 other 0.0383430632989338 1 0.0135065033778671 4.96218508380649 -0.288684547122215 8.13458123448318e-18 91.6361547403424 71.0870546083484 1.2890695112522 0.198310823061696 -728.764172366251 100.769339855832 -7.23200304188632 3.57300328675478e-12 RBM5 other 1.15787629291634e-13 5.47455563596567e-08 1 1.2890695112522 -7.23200304188632 9.81088048596087e-09 5.8005652664815 3.22015524523231 1.80133093740424 0.0725919868236183 -21.0478989925889 5.98789109087453 -3.51507712367475 0.000503049212892565 MTMR7 other 0.000113953376844436 1 1 1.80133093740424 -3.51507712367475 0.00480612066910814 66.4328287766057 106.35795949607 0.624615488030873 0.532668540146824 -419.091267097989 197.773035648835 -2.11905159731747 0.0348560709444962 SLC7A2 other 1 1 1 0.624615488030873 -2.11905159731747 8.94729915108907e-11 335.705881259291 129.543678865121 2.59144934125906 0.00999796754219914 -1409.69919531143 300.234225623364 -4.69533142793607 3.96392329362513e-06 ARF5 other 1.12100711063995e-06 0.0588920083733886 1 2.59144934125906 -4.69533142793607 8.28764138058311e-07 111.256044336409 21.2487191162545 5.23589416038267 3.03486285699927e-07 -47.1853664085963 68.0509195591511 -0.693383230002968 0.488588263681268 SARM1 other 0.00862992096960119 1 0.00370405011696761 5.23589416038267 -0.693383230002968 3.77771958280899e-43 865.708926405704 53.1075854870313 16.301040961787 1.41266720370008e-43 -72.606299233792 170.08178272704 -0.426890511550646 0.669755397990457 POLDIP2 other 5.77764432994806e-39 1 2.16194588854261e-39 16.301040961787 -0.426890511550646 0.00655131409588055 221.880303473138 69.7774183056116 3.1798296477715 0.00161782317171856 255.597800987393 279.981279349597 0.912910325937338 0.361976976014118 PLXND1 other 1 1 1 3.1798296477715 0.912910325937338 5.4492442949073e-06 161.181691944238 93.5289920388289 1.72333399976473 0.0858001768916541 -921.082915647246 218.566480402017 -4.21420024677648 3.2696212974333e-05 AK2 other 0.0532282182726545 0.47455283510947 1 1.72333399976473 -4.21420024677648 0.845703887904866 22.3394965265011 49.1584121957993 0.454438935853385 0.64982199901171 50.9819786747814 92.235278861081 0.552738380631638 0.580829672040351 CD38 other 1 1 1 0.454438935853385 0.552738380631638 5.58024537381289e-17 1681.02490928669 187.865402921938 8.94802812620691 3.21641776552148e-17 -667.3801547842 919.64527178265 -0.725693020190865 0.468567500723719 FKBP4 other 7.86312375623974e-13 1 4.70272441496896e-13 8.94802812620691 -0.725693020190865 1.61746680694133e-07 492.369804559816 105.465839650823 4.66852400919538 4.46935367236129e-06 -370.426836440225 203.751687911282 -1.81803076203971 0.0699943276306699 KDM1A other 0.00176384755296952 1 0.05131264951238 4.66852400919538 -1.81803076203971 1.32423070457909e-14 92.9281852342461 66.3356961528886 1.40087751578076 0.162225769527527 -589.704072161697 94.0340593239122 -6.27117532095884 1.16824029584488e-09 RBM6 other 1.8083694501732e-10 1.78250104340011e-05 1 1.40087751578076 -6.27117532095884 0.000120362843575357 98.0920766947564 22.9027612251589 4.2829803677559 2.44136975032655e-05 -12.1864497020623 43.4050940691693 -0.280760817673664 0.779075292979269 CAMKK1 other 1 1 0.266670817828169 4.2829803677559 -0.280760817673664 9.25876895340393e-08 189.483137297611 34.4378049609477 5.50218393746303 7.88170139087702e-08 -137.389650319186 140.620485586225 -0.977024433861322 0.329321331433734 RECQL other 0.00102448278469415 1 0.000985291490873537 5.50218393746303 -0.977024433861322 3.78128461055615e-09 67.3400648488671 11.6167975785899 5.79678387208681 1.66353295764469e-08 -70.9449818292602 50.2209146251628 -1.41265809989278 0.15875943176468 VPS50 other 4.47439407967109e-05 1 0.000213531090443272 5.79678387208681 -1.41265809989278 0.640740754734814 125.665440326356 235.050039185023 0.534632713791794 0.593277457175424 -738.444266686718 1109.65400829342 -0.665472535734266 0.506230685941808 HSPB6 other 1 1 1 0.534632713791794 -0.665472535734266 0.0272013644452448 10.3447908898128 8.61275759002443 1.20110089964618 0.230603102292487 -87.533789531551 40.6588220577279 -2.15288552647368 0.0320771479625779 ARHGAP33 other 1 1 1 1.20110089964618 -2.15288552647368 0.118469261370257 34.2841531601669 53.3849135993376 0.642206774323453 0.521203086633721 -294.9279243299 170.272498044974 -1.7320937186932 0.0842296060429741 NDUFAB1 essential 1 1 1 0.642206774323453 -1.7320937186932 0.0475528615523422 148.941141207304 187.611914219767 0.79387890596775 0.427865462230277 1977.89535688027 801.189624408273 2.46869816660577 0.0140927122198606 PDK4 other 1 1 1 0.79387890596775 2.46869816660577 0.554106119812061 -46.0309430076161 42.4844084616242 -1.08347849656882 0.279419492621079 -39.7731423931464 60.4580615385518 -0.657863341645258 0.511103379157172 ZMYND10 other 1 1 1 -1.08347849656882 -0.657863341645258 2.20156421489086e-15 156.871250109628 19.0712920927664 8.22551767056872 5.26658078930511e-15 -67.5142386207106 81.305162065025 -0.830380715147152 0.406956484550208 SLC25A13 other 3.04542377845852e-11 1 7.58703628507295e-11 8.22551767056872 -0.830380715147152 6.93210078725553e-07 202.112016911992 39.4240134121686 5.12662206150752 5.12475128911699e-07 -134.212152820049 94.7898151816483 -1.41589212472727 0.157782711091253 CDC27 essential 0.00725305705370547 1 0.00619069955725333 5.12662206150752 -1.41589212472727 2.54049430311709e-17 338.359782010008 37.0719001705997 9.12712271162051 8.11336071053666e-18 -93.8924000215016 70.7627670624272 -1.3268616239762 0.185500482087617 DVL2 other 3.59556158720161e-13 1 1.19031114984283e-13 9.12712271162051 -1.3268616239762 0.00418259792790541 243.01768318029 96.5492393420792 2.51703363834142 0.0123231025639739 -389.517237595543 276.496611907053 -1.40875953202089 0.159877195017979 PRSS22 other 1 1 1 2.51703363834142 -1.40875953202089 1.30638810307197e-10 538.798202819734 116.426180878039 4.62780964518752 5.3766256241087e-06 -994.289336882755 274.336209477209 -3.62434597597427 0.00033686680854661 UPF1 essential 1.62684510475552e-06 1 0.0614655841348106 4.62780964518752 -3.62434597597427 8.36555670924429e-07 108.102691480685 23.4589100979128 4.60817194956995 5.89490824162965e-06 -187.363798600439 97.074441735431 -1.93010431222551 0.0544858319493435 SKAP2 other 0.00871021764566515 1 0.067201953954578 4.60817194956995 -1.93010431222551 1.38556544599177e-07 56.1997068489058 34.9735990785911 1.60691802758465 0.109064793204018 -297.712777279856 64.0458846665124 -4.64842946318955 4.90825504415041e-06 MCUB other 0.00151719416336099 0.0727845140497064 1 1.60691802758465 -4.64842946318955 0.0171156848768049 14.1650513164693 5.11902772840309 2.76713705570964 0.0059872609770768 -5.11826596288807 21.0132563949219 -0.243573193354503 0.807718941607821 HOXA11 og 1 1 1 2.76713705570964 -0.243573193354503 1.14226341199595e-07 171.7732068363 30.752363766235 5.58569117294656 5.01268720482391e-08 -17.4879534782135 121.216603989458 -0.14427028066002 0.885378720198282 POLR2J essential 0.00125648975319554 1 0.000631598587807813 5.58569117294656 -0.14427028066002 2.00776637191851e-15 239.194244067383 27.5850369394473 8.67115909949459 2.18277487061488e-16 -4.09102163718989 51.6742957063075 -0.0791693738883514 0.936947388659667 DHX33 essential 2.7789494353724e-11 1 3.17702882417996e-12 8.67115909949459 -0.0791693738883514 0.716903527185556 12.6151876239767 15.4548602128187 0.816260221720628 0.41496042707405 2.62223982931182 37.2469612659703 0.0704014432368624 0.943918255955331 MEOX1 other 1 1 1 0.816260221720628 0.0704014432368624 0.647689505415636 -0.366253084805132 2.61397120371621 -0.140113664712312 0.88865860962475 -10.3641540363629 11.1149611422794 -0.932450766466416 0.351808810047607 THSD7A other 1 1 1 -0.140113664712312 -0.932450766466416 6.69588898372731e-10 192.643468526147 32.3566588158619 5.95375034308886 6.9685661883693e-09 -194.146791152347 79.9369649992719 -2.42874859151977 0.0157085130355766 LIG3 other 8.14889689319613e-06 1 9.05147062207289e-05 5.95375034308886 -2.42874859151977 0.00301329558367119 63.9817336068464 21.0292507224718 3.04251133106116 0.00254223234780113 -55.7406212745542 55.3281190616508 -1.00745556183545 0.314484276739096 RPAP3 essential 1 1 1 3.04251133106116 -1.00745556183545 0.451475659073709 -0.708488925629118 8.45943405523614 -0.083751338565088 0.93330683510879 -32.1959251446652 26.0516777548007 -1.23584843355174 0.217427040958457 ACSM3 other 1 1 1 -0.083751338565088 -1.23584843355174 8.11521490578485e-20 197.470932343318 34.3008473890845 5.75702781051871 2.00659430922038e-08 -434.490081648966 90.8511708266399 -4.78243788930414 2.64669334232806e-06 CIAPIN1 essential 1.17621924844446e-15 0.0394198506406342 0.000256884203466393 5.75702781051871 -4.78243788930414 3.92409628424994e-08 132.302965916 50.936564716449 2.59740653207568 0.00982980888791963 -305.180967164981 88.4485246707611 -3.4503793963888 0.000635374069205683 SPPL2B other 0.000442363374123496 1 1 2.59740653207568 -3.4503793963888 1.63454655302153e-26 306.033163215094 26.4727627245787 11.5603031840328 6.26845694954092e-26 -81.5907981711618 82.9692882252015 -0.983385538389842 0.326187069546178 FAM214B other 2.44920455504746e-22 1 9.46098207394211e-22 11.5603031840328 -0.983385538389842 0.051744046435984 82.2546744248891 46.1660390162889 1.78171392169614 0.0757471203727666 199.501996534977 109.787823694305 1.81715958857582 0.0701308504389742 COPZ2 other 1 1 1 1.78171392169614 1.81715958857582 0.647702460204718 16.8086941149203 19.2286150644917 0.874150013328829 0.382702519983304 34.7937342727136 63.0602472660836 0.551753850978429 0.581508215108714 PRKAR2B other 1 1 1 0.874150013328829 0.551753850978429 6.72317711760712e-05 327.989055947633 107.526326230357 3.05031397841093 0.00247771797197239 -719.137152438775 312.600796588304 -2.30049686465093 0.0220649530190869 CREBBP og 0.590496646239433 1 1 3.05031397841093 -2.30049686465093 0.329023340857247 -27.2398286028494 21.1232465506864 -1.28956638069276 0.198141321604358 -46.6480236377663 49.7905884079502 -0.936884361670205 0.349531252461102 TSPOAP1 other 1 1 1 -1.28956638069276 -0.936884361670205 0.041257330260585 33.5716893000149 13.9163229425766 2.41239653883737 0.0164101979093871 -36.7035468568774 57.3894625094781 -0.639552023175259 0.522921459095786 GCFC2 other 1 1 1 2.41239653883737 -0.639552023175259 0.0167744545372731 85.1392180559693 31.1086766774954 2.73683187936955 0.00655002669414022 -92.6674540517631 128.727404015617 -0.719873555754457 0.472128296595161 WDR54 other 1 1 1 2.73683187936955 -0.719873555754457 0.00186087425701686 9.77017645818129 26.105740506305 0.374253948315377 0.708470428532812 -334.215323289172 101.340817930642 -3.29793394324003 0.00108688359680572 CROT other 1 1 1 0.374253948315377 -3.29793394324003 0.752094873007142 0.442085809405161 1.53888139147449 0.287277376836413 0.774091877213216 -3.48996600763305 5.97383609246825 -0.584208530935952 0.559504900529811 ABCB4 other 1 1 1 0.287277376836413 -0.584208530935952 1.52602491166516e-11 329.189404987258 49.7173311864047 6.62122034976156 1.54307337371075e-10 -285.763251926551 192.306647768773 -1.48597698125417 0.138288529524464 KMT2E other 1.9528540794579e-07 1 2.08916704066699e-06 6.62122034976156 -1.48597698125417 2.98888475316097e-08 462.028730311779 89.5523685357693 5.15931334777855 4.36388272629904e-07 -512.373418710733 310.236758537232 -1.65155612483374 0.0996090732726064 RHBDD2 other 0.000339148752941175 1 0.00528858947600181 5.15931334777855 -1.65155612483374 0.468920933385298 -17.5161867833037 29.0932897952864 -0.602069649274987 0.547556803893781 -94.8330752554973 78.5453441712584 -1.20736723807239 0.228188003066671 SOX8 other 1 1 1 -0.602069649274987 -1.20736723807239 7.2829175928413e-09 109.602903336479 37.8808838382561 2.89335654903042 0.00407461114241852 -378.555672298939 80.8958121670687 -4.67954597596639 4.26031480610366e-06 IBTK other 8.50717604019792e-05 0.0632486336114149 1 2.89335654903042 -4.67954597596639 0.000430262800764683 22.7761408035243 14.0392657439859 1.62231709398912 0.105720234238477 -64.6888091180147 27.7636360508117 -2.3299833278186 0.0204285891629894 ZNF195 other 1 1 1 1.62231709398912 -2.3299833278186 0.000193611994990346 301.56060620503 104.09797707937 2.89689208825935 0.00405188202371853 -456.500169230379 213.146681548194 -2.14171839746499 0.0330378088980183 MYCBP2 other 1 1 1 2.89689208825935 -2.14171839746499 6.70438324782825e-16 291.049441119703 38.1607427489676 7.62693333917295 3.35536105533905e-13 -181.679861197162 78.1363472236841 -2.32516450605325 0.0207437653579975 FBXL3 other 9.33250148097693e-12 1 4.73743427403321e-09 7.62693333917295 -2.32516450605325 0.0257887281715109 -124.527617118524 46.2416893898418 -2.69297291603449 0.00746204596006582 -180.685076697331 159.174873605372 -1.13513566937259 0.257184213211504 ITGAL other 1 1 1 -2.69297291603449 -1.13513566937259 0.000234558972246435 179.641432747021 43.6789614302342 4.11276795200253 4.97935488490987e-05 78.4879635875177 104.183662878137 0.753361529238274 0.451788341073154 PDK2 other 1 1 0.531396753317582 4.11276795200253 0.753361529238274 0.101012520413707 1431.38919732269 945.497512487971 1.51390054274828 0.131041197586077 -3218.78623116971 2255.2137429023 -1.42726437407541 0.154481815440663 ITGA3 other 1 1 1 1.51390054274828 -1.42726437407541 0.762881912687011 -2.83676651888863 4.4831969776992 -0.632755271070974 0.527345357514822 -4.58102889427747 10.808217102275 -0.423846861228688 0.67196226306188 ITGA2B other 1 1 1 -0.632755271070974 -0.423846861228688 4.34937673425871e-05 129.022049810725 50.4342330916523 2.55822368858584 0.0109824721909337 -448.431894021708 154.838605279341 -2.89612460156626 0.00403893538999668 GDE1 other 0.390791499573145 1 1 2.55822368858584 -2.89612460156626 0.00571394636596522 193.226468533009 68.8158099954411 2.80787901131745 0.00529402786768333 -117.563635350688 160.527487709118 -0.732358283484246 0.464487649282211 CRLF1 other 1 1 1 2.80787901131745 -0.732358283484246 0.847859533179223 1.23136816522441 9.81034844603361 0.125517271073309 0.900193118482159 -12.7937800516877 23.330067480834 -0.548381613649337 0.583813459909658 OSBPL7 other 1 1 1 0.125517271073309 -0.548381613649337 8.66084309960245e-06 228.73910641972 49.9742534595534 4.57713903830199 6.77698497995604e-06 297.211747246261 123.936596376853 2.39809512230376 0.0170584607254318 TMEM98 other 0.0831267720699843 1 0.0770001033422605 4.57713903830199 2.39809512230376 6.87795503836069e-07 -20.1304103081855 19.206572620429 -1.04810008042631 0.295383461655478 -197.507167642899 36.6614664517486 -5.38732316948762 1.38867402148859e-07 YBX2 other 0.00719846774314829 0.00209689777244777 1 -1.04810008042631 -5.38732316948762 0.0130371849362537 4.00735342286277 1.66906471810575 2.40095748199074 0.0169244053148548 -7.56770389780543 4.86884553229837 -1.55431176602414 0.121101585952827 KRT33A other 1 1 1 2.40095748199074 -1.55431176602414 0.224916564581149 -5.03401963889778 50.1944494287822 -0.100290364695408 0.920176609739902 -210.996016322272 121.904910594443 -1.7308245852722 0.084447012280621 MAP3K14 other 1 1 1 -0.100290364695408 -1.7308245852722 6.41370608217699e-10 804.176156964338 121.59809370862 6.61339444096344 1.57627668726203e-10 186.107339083004 566.080005254884 0.328765081535087 0.742548305130177 TMEM132A other 7.81125263748336e-06 1 2.13349049620915e-06 6.61339444096344 0.328765081535087 6.73615301455236e-07 894.075868083359 176.030938443855 5.07908368828315 6.47506236846715e-07 -578.770581948323 428.405776177137 -1.35098687770497 0.177660078771253 AP2B1 other 0.00705409943683923 1 0.00778431997937121 5.07908368828315 -1.35098687770497 8.49433668523997e-05 97.2414350953133 23.8328458138644 4.08014367460661 5.68809906404128e-05 -32.2985640837546 68.4916774448428 -0.471569178748251 0.63755568690663 ZNF263 other 0.737053594178272 1 0.603336667722858 4.08014367460661 -0.471569178748251 0.0414450879683892 -380.453798993363 179.251468472113 -2.12245847822749 0.0345669460068272 136.227069406598 476.230830875673 0.286052604271986 0.775022922078566 CX3CL1 other 1 1 1 -2.12245847822749 0.286052604271986 0.0806863885457075 96.3836656580957 46.7320604073848 2.06247413056208 0.0399719085546103 117.02304836969 112.725922468827 1.03812012185619 0.300000368085552 SPATA20 other 1 1 1 2.06247413056208 1.03812012185619 0.006531646115752 24.4263560733615 10.9908487996445 2.22242672232481 0.0269553790214605 64.644422278183 26.5118541501231 2.4383214358428 0.0153010028046518 CACNA1G other 1 1 1 2.22242672232481 2.4383214358428 0.000192731229304116 554.488601681576 153.029085697402 3.6234196862289 0.000338183585658311 -447.134340637201 439.71622779561 -1.01687022759833 0.309985771988494 TNFRSF12A other 1 1 1 3.6234196862289 -1.01687022759833 0.0369624660354144 24.4821020621592 9.48283514116534 2.5817281116574 0.0102836593999296 22.4675344454711 40.5213233535437 0.554462011258727 0.579657388055047 DLX6 other 1 1 1 2.5817281116574 0.554462011258727 7.5276286254035e-05 124.769433021451 32.5787794309645 3.82977616720851 0.000154500798925065 -122.375707469445 99.509160687561 -1.22979338408532 0.219683548665818 MAP3K9 other 0.657688913001504 1 1 3.82977616720851 -1.22979338408532 1.90180565231065e-07 198.561370855052 43.7141339818009 4.54226934788911 7.89431428749555e-06 -470.781520117208 181.912960711414 -2.58794930430523 0.0100951680490939 RALA other 0.00206669220236598 1 0.0892610116487122 4.54226934788911 -2.58794930430523 1.42168887399975e-16 385.383272499583 48.087269657135 8.01424733089211 2.16270151764588e-14 -512.303877623532 214.803963112651 -2.38498335971046 0.0176691602790497 BAIAP2L1 other 1.99477165910906e-12 1 3.09958381509007e-10 8.01424733089211 -2.38498335971046 1.02858530630322e-09 274.917125815668 59.4704641800806 4.6227506310225 5.50103043164092e-06 -277.004002340138 130.866990658156 -2.11668351925133 0.0350582579756527 KDM7A other 1.24191389883051e-05 1 0.0628327695902026 4.6227506310225 -2.11668351925133 0.465621900566802 -21.3394129414437 19.7687257167022 -1.0794531345748 0.281201257799068 -66.3363914570818 85.207343408916 -0.778529042253187 0.43683428230326 ETV1 other 1 1 1 -1.0794531345748 -0.778529042253187 1.5652891181579e-17 90.7504899036172 19.6205385190247 4.62528028043791 5.44460009952155e-06 -210.438157313356 43.0506330284999 -4.88815477287045 1.6152715269761e-06 AGK other 2.2216148454015e-13 0.0241353871560769 0.0622154453372328 4.62528028043791 -4.88815477287045 0.515310960606306 -1.56909906181015 29.1401073778481 -0.0538467151635468 0.957092775110702 -160.978771523179 142.64497758435 -1.12852744098886 0.25998997205624 ALDH3B1 other 1 1 1 -0.0538467151635468 -1.12852744098886 0.0393237347451899 38.2587775976689 67.0789096527925 0.570354792522723 0.568839846590498 -367.523224370904 160.717391019838 -2.28676698917754 0.022866282834952 TTC22 other 1 1 1 0.570354792522723 -2.28676698917754 4.01856160897753e-06 147.120252394859 30.14941308888 4.8797053515155 1.68331227197751e-06 -12.5542070466116 106.326801316274 -0.118071896184185 0.906085235114791 PHTF2 other 0.0396672216422172 1 0.0198260519393511 4.8797053515155 -0.118071896184185 0.205903545853877 15.6731124517788 10.9204666967805 1.43520537051767 0.152208307806198 53.1374798919879 37.8318323135112 1.40457061269566 0.161121933438403 CCL26 other 1 1 1 1.43520537051767 1.40457061269566 1.31153810295843e-09 177.595557561197 44.5018847756811 3.99074237993281 8.18210473517684e-05 -234.449551278473 80.5625702955489 -2.91015480785159 0.00386731457811145 FARP2 other 1.57804264547958e-05 1 0.855684513204794 3.99074237993281 -2.91015480785159 0.411020113028859 2.66246325560837 5.29647999124382 0.502685417486702 0.615532318061196 14.6712849486131 11.0207643826517 1.3312402333642 0.184060561384577 USH1C other 1 1 1 0.502685417486702 1.3312402333642 0.0420698523925369 95.2456526543543 47.36236819245 2.01099852666441 0.0451666054563249 -213.666167206868 192.372953989749 -1.11068714585655 0.267539511132347 GGCT other 1 1 1 2.01099852666441 -1.11068714585655 8.62219908823836e-05 55.912031846096 13.106731278694 4.26590205118383 2.64059992386076e-05 3.76235665844432 50.6249473394111 0.0743182335226916 0.940804642157125 DBF4 other 0.747803326922913 1 0.287746173703107 4.26590205118383 0.0743182335226916 0.106856340690441 7.85711875369085 3.94593693004367 1.99119217893933 0.0473177864285238 1.96069429993531 7.01115518366206 0.279653530491563 0.779925713986111 TBXA2R other 1 1 1 1.99119217893933 0.279653530491563 1.16994405797255e-06 153.157190681151 33.8016839666241 4.5310520870019 8.35144696905858e-06 -122.639707590353 95.156850750944 -1.28881637656695 0.198410647940971 IFRD1 other 0.0120562735174072 1 0.0942878362806714 4.5310520870019 -1.28881637656695 7.55648525054862e-19 101.823821820301 11.1302154758611 9.14841424598955 7.03068922015926e-18 -64.0697947024155 23.0644201431587 -2.77786279927005 0.00579569627142965 COX10 other 1.08594249535634e-14 1 1.03196456373498e-13 9.14841424598955 -2.77786279927005 1.43881202463923e-08 251.620657693713 41.9062738790256 6.00436723198268 5.25600221389844e-09 30.1001288209355 142.907830836867 0.210626168241932 0.833314314754684 GTF2IRD1 other 0.000165679204637207 1 6.85382688692357e-05 6.00436723198268 0.210626168241932 4.05817434276582e-12 305.14248958394 54.9609102223167 5.55199119428044 5.9516492528081e-08 -605.256041844239 172.367652161993 -3.51142476127373 0.000509959349937292 PAF1 essential 5.27359755842419e-08 1 0.000747646179137753 5.55199119428044 -3.51142476127373 9.98004853258813e-15 209.708030885282 25.9907068340704 8.06857744285671 1.44711981079947e-14 -114.258255052661 108.977113847514 -1.04846101184637 0.295217476809792 VPS41 essential 1.3669672475086e-10 1 2.07676164047832e-10 8.06857744285671 -1.04846101184637 0.911133529434139 3.68258720462959 10.0842068723638 0.365183623386574 0.715217105082784 4.53853151349529 18.4975086774186 0.245359069301903 0.806336685908091 ARHGAP44 other 1 1 1 0.365183623386574 0.245359069301903 2.99075619296547e-16 369.73610887853 46.2924482259531 7.98696381478574 2.55808930836366e-14 -314.070297087578 84.9144581816577 -3.69866691506983 0.000255260651649049 ELAC2 essential 4.18197438462362e-12 1 3.66292808064593e-10 7.98696381478574 -3.69866691506983 0.144496462060371 -48.958022507641 25.1743455063397 -1.94475850406167 0.0526826160799121 0.142602929501692 108.506695544928 0.00131423161294822 0.99895221665684 SCIN other 1 1 1 -1.94475850406167 0.00131423161294822 0.138915388713615 33.8282248304204 19.6548626920522 1.72111224384689 0.0862314011085143 39.857338642106 37.3377676735459 1.06748049295795 0.286588193374666 MYH13 other 1 1 1 1.72111224384689 1.06748049295795 3.72408165220068e-30 787.135247712078 62.3215495509216 12.6302258750631 7.8074654703007e-30 -368.144030572271 304.892631308506 -1.20745466688489 0.228168718619062 ADIPOR2 other 5.62969423363177e-26 1 1.18564170631986e-25 12.6302258750631 -1.20745466688489 0.0103468948554254 0.85340593458011 1.87276288877156 0.455693531571369 0.648920408863434 -7.35545876827823 2.79652282629363 -2.63021588778762 0.00894693714904557 CDKL3 other 1 1 1 0.455693531571369 -2.63021588778762 0.0555736487378865 116.428402589154 53.5235422158658 2.17527461317091 0.0303412683716769 246.967195894602 153.280110550816 1.61121488630925 0.10811876157241 PRSS21 other 1 1 1 2.17527461317091 1.61121488630925 1.536648454075e-11 280.255850638467 40.6404561803772 6.89598191010921 2.87761305966113e-11 -79.8610872748386 98.5044739660112 -0.810735635240228 0.418121937942648 MARK4 other 1.96629536183437e-07 1 3.94866064046701e-07 6.89598191010921 -0.810735635240228 0.259553375285576 45.3670984307525 82.8268739170121 0.547734041927115 0.584257569292162 247.177421472971 155.406968445169 1.59051697582132 0.112708815913253 PROM1 other 1 1 1 0.547734041927115 1.59051697582132 0.000464996607340287 126.312383115262 75.2260766037793 1.67910369406286 0.0941109980263592 -506.918212308842 173.76898887504 -2.91719607503369 0.00378252038512593 CCDC124 other 1 1 1 1.67910369406286 -2.91719607503369 0.0265544551802786 -3.18363226683361 2.04494507958914 -1.55683020468855 0.120508571712044 -13.8038607728463 5.39640527988238 -2.55797332796828 0.0109931582016782 CEACAM21 other 1 1 1 -1.55683020468855 -2.55797332796828 1.95584840408176e-13 616.95609445053 79.5448877602131 7.75607473745309 1.19887629586142e-13 -250.024843497133 151.091692917342 -1.65478881511979 0.0989539308328966 PAFAH1B1 essential 2.61496931625731e-09 1 1.70396287930784e-09 7.75607473745309 -1.65478881511979 0.148954409467757 -179.670095823712 122.174778891454 -1.47059890309554 0.142423785555467 -442.783518448527 296.761506808643 -1.49205172601459 0.136712452227152 NOS2 other 1 1 1 -1.47059890309554 -1.49205172601459 0.219939991358593 -30.5678427464472 19.3873299487286 -1.57669172739549 0.115857610736145 23.8363144593663 35.7993940544015 0.665830109390794 0.506000870161966 DNAH9 other 1 1 1 -1.57669172739549 0.665830109390794 5.72328171499645e-22 1019.55697795661 103.586533738432 9.84256293903135 4.31776885916715e-20 -964.531055520748 329.161549403497 -2.93026648242682 0.00363579848316338 KIAA0100 other 8.41036248018728e-18 1 6.41620452472239e-16 9.84256293903135 -2.93026648242682 0.475165247749545 -2.6279359994971 6.4104569372621 -0.409945191928781 0.682128390875264 -24.502904746461 20.5314382043491 -1.1934334313351 0.233609259337134 SLC13A2 other 1 1 1 -0.409945191928781 -1.1934334313351 0.0282125073972558 56.5490789533692 46.6144337656523 1.21312379847113 0.225980023406739 212.920668154903 86.6016098124677 2.45862252001983 0.0144780165712442 GAS7 other 1 1 1 1.21312379847113 2.45862252001983 0.00687414739891715 86.0640066759527 30.8296632864832 2.79159736115854 0.00556003056895121 -60.1019294001972 73.9594541524685 -0.812633490727179 0.417032371128691 TRAPPC6A other 1 1 1 2.79159736115854 -0.812633490727179 0.0226722824587324 34.7943594748665 15.4735691293099 2.24863179167626 0.0252224670317241 -10.7648017414606 27.5401751080462 -0.390876299777614 0.696151238204166 MATK other 1 1 1 2.24863179167626 -0.390876299777614 0.948627494046684 -19.8187428883686 61.8035240400064 -0.320673346645082 0.748669236777655 -22.362275583716 163.093310805118 -0.137113382966619 0.891028217139227 CEACAM7 other 1 1 1 -0.320673346645082 -0.137113382966619 0.113922290350895 -26.2860654187938 12.5987675493461 -2.08639974631154 0.0377363489745108 -11.3685290224995 29.0527084314583 -0.391307029061347 0.695831543264925 CD79B og 1 1 1 -2.08639974631154 -0.391307029061347 0.189294828275434 32.4652202684818 31.3412064813073 1.03586376892813 0.301050294556926 117.064700321422 72.2726989148088 1.61976378465417 0.106271150172674 SCN4A other 1 1 1 1.03586376892813 1.61976378465417 0.306477839494535 22.2671298481033 27.4805911703732 0.810285692547601 0.418381947416337 -40.1807503798047 50.5144208703859 -0.795431278582877 0.426955988611905 ST7L other 1 1 1 0.810285692547601 -0.795431278582877 0.195911609514941 21.9166631488853 18.4564068785431 1.18748266079705 0.235920748929016 -30.2522958798694 41.7892376275493 -0.7239255271775 0.469642002583343 PAX6 other 1 1 1 1.18748266079705 -0.7239255271775 0.000756794511280234 59.1912535293666 33.9519466436653 1.74338320422668 0.0822331592595362 -249.806034616766 91.6540396927637 -2.72553218007792 0.00677537138461015 RPUSD1 other 1 1 1 1.74338320422668 -2.72553218007792 8.83767381450716e-10 108.869914212684 27.7182419962714 3.92773517986203 0.000105466554831394 -294.790249005102 74.7629971517018 -3.94299667263128 9.92704986323142e-05 RHBDF1 other 1.07131429866492e-05 1 1 3.92773517986203 -3.94299667263128 0.0019602056269052 104.059844700529 33.6282443298191 3.09441800410188 0.00214883849551427 -67.7458729090375 90.7206521203167 -0.74675249048244 0.455769969562145 LUC7L other 1 1 1 3.09441800410188 -0.74675249048244 0.471189256328199 6.58568253020279 6.28492685737004 1.04785348814045 0.295501869878853 0.152923550973666 8.95323323100008 0.0170802599494646 0.986383298123629 CACNA2D2 other 1 1 1 1.04785348814045 0.0170802599494646 0.00085540849625995 79.7731180388678 23.4471765684857 3.40224836051635 0.00075319963624925 -37.768315855238 64.7154229129485 -0.583606104313677 0.559896464328976 BAIAP3 other 1 1 1 3.40224836051635 -0.583606104313677 0.00150576124364793 215.137707582305 69.4899871832408 3.09595261566245 0.0021352605600292 -178.817259022799 193.131935394009 -0.925881360107498 0.355205365585128 TSR3 other 1 1 1 3.09595261566245 -0.925881360107498 0.0085763918785728 112.632112787119 46.8020424618011 2.40656404854653 0.0166733088357912 -144.616360293599 126.34316089492 -1.1446314883152 0.253222632627513 PIGQ other 1 1 1 2.40656404854653 -1.1446314883152 0.000258109746491869 63.0422442852284 28.3167921675289 2.22632012525484 0.0266886895136316 -211.050752845299 79.2821936328753 -2.66201959323417 0.0081596198221288 CRAMP1 other 1 1 1 2.22632012525484 -2.66201959323417 1.24842473425637e-14 301.890606308553 38.5713980077116 7.82679969878707 7.38051970974342e-14 -10.8251643292904 89.2517594037147 -0.121287965655945 0.903539076014638 TEAD3 other 1.70609724183475e-10 1 1.05194547422973e-09 7.82679969878707 -0.121287965655945 0.552378669734616 -40.9827644171294 60.4392151587382 -0.678082339578564 0.498209502636184 -159.311546546746 191.472345670891 -0.83203423444018 0.406010092439034 SELE other 1 1 1 -0.678082339578564 -0.83203423444018 3.55940304346222e-17 229.913890438353 38.3012546231541 6.0027770030114 5.27137758178535e-09 -418.446492808083 85.4718754612377 -4.89572143526735 1.55852452393432e-06 DNAJC11 essential 5.02587709736865e-13 0.0232921490101984 6.87334922888992e-05 6.0027770030114 -4.89572143526735 0.25379379317057 132.830995364167 90.6728647135827 1.46494759798043 0.143916993106925 215.393884456014 292.363543535184 0.736733047669101 0.461824480681532 FMO3 other 1 1 1 1.46494759798043 0.736733047669101 0.582280296616065 56.5996200779071 55.8282746654238 1.01381639352292 0.311436299198853 81.9034777537863 132.134581207778 0.619848922251439 0.53579837071108 MYLIP other 1 1 1 1.01381639352292 0.619848922251439 0.0481105376933828 11.8115417755107 45.8540984255325 0.257589663325139 0.796889174402996 -201.919131893631 88.5865032960879 -2.27934419331063 0.0233046843413647 E2F2 other 1 1 1 0.257589663325139 -2.27934419331063 2.42738519422336e-05 698.55184371524 214.542464644173 3.25600735907372 0.00125254336534371 -1237.40179329885 495.638093555153 -2.49658331227754 0.0130485799214484 PSMB1 essential 0.223537902536029 1 1 3.25600735907372 -2.49658331227754 1.04180328015457e-12 406.023524507853 60.4869772650592 6.71257753100511 8.75128056100153e-11 -120.576042938814 143.033776019286 -0.842990000645414 0.399865658404859 JARID2 other 1.37174237897953e-08 1 1.19017415629621e-06 6.71257753100511 -0.842990000645414 1.0870261367597e-12 159.536130638748 24.8139050918503 6.42930365245676 4.71017735148486e-10 -133.620660622653 55.7252794065249 -2.39784640015655 0.0170698355414554 CDK11A other 1.4308525038168e-08 1 6.31823189928179e-06 6.42930365245676 -2.39784640015655 7.22276717498909e-10 203.505882953999 45.7988031481712 4.44347600734465 1.22378155104738e-05 -369.187571025573 102.43377108029 -3.60415873722149 0.000363370627023527 NADK other 8.78216260806923e-06 1 0.136488356388314 4.44347600734465 -3.60415873722149 1.60980499049993e-05 -0.510300261879076 29.4027379481553 -0.0173555354871668 0.986163797259301 -170.790262479259 42.1176506565279 -4.05507571806567 6.3003581902571e-05 DLEC1 other 0.150935315909274 0.905550482685653 1 -0.0173555354871668 -4.05507571806567 5.30572354285424e-23 234.520798594685 21.9677888668591 10.6756669966219 5.96273336955582e-23 -104.869199776638 105.268071750218 -0.99621089313267 0.319902746117249 CYTH3 other 7.84557340281857e-19 1 8.94231123432287e-19 10.6756669966219 -0.99621089313267 0.127148359099925 -16.7973418872823 9.42071262956248 -1.78302242598631 0.0755516547555233 -51.2023509895496 36.387644686559 -1.40713562063727 0.160379385549376 ADAM22 other 1 1 1 -1.78302242598631 -1.40713562063727 2.29828997946737e-15 970.330289967135 132.795690011064 7.30694113556162 2.24735066310304e-12 -1123.63493749085 448.375258966741 -2.50601458269623 0.0127123696089915 SYPL1 other 3.17853504160337e-11 1 3.1406725516865e-08 7.30694113556162 -2.50601458269623 0.00221679381264827 211.654140669314 69.3543449365883 3.05177910429163 0.00246600242805688 -223.958423142371 159.930846728105 -1.40034538504706 0.162381793450299 CYB561 other 1 1 1 3.05177910429163 -1.40034538504706 2.13805128418873e-11 603.291898828841 89.3231213975013 6.75403959680385 6.81834393956962e-11 -489.840443997175 212.978713289101 -2.29995024588329 0.0220963006064459 SPAG9 other 2.72729821811114e-07 1 9.29135728645152e-07 6.75403959680385 -2.29995024588329 0.192958978198689 10.1918568400049 11.3599669810251 0.897173104202559 0.370303140449631 -30.3024741526233 28.9888518246437 -1.04531474154015 0.296668964176583 AASS other 1 1 1 0.897173104202559 -1.04531474154015 1.35815083056111e-24 352.894365928355 31.5501995290135 11.1851706549061 9.78943179967844e-25 -133.995471911337 166.996449710407 -0.802385153359263 0.422925691899784 PLEKHG6 other 2.02079262079187e-20 1 1.47419053471358e-20 11.1851706549061 -0.802385153359263 2.85450071059274e-16 55.8708114324938 18.462050833946 3.02625163016909 0.00267695052228165 -147.644597633994 26.3292997842798 -5.6076158061046 4.43749751189841e-08 SS18L2 essential 3.99316104404818e-12 0.000672058998177014 1 3.02625163016909 -5.6076158061046 8.85684555650026e-06 87.1608117402791 29.6537410086411 2.93928552606164 0.00352898750955224 -117.947122800026 54.9502114568423 -2.14643619511202 0.0325897132393979 MPND other 0.084928292041281 1 1 2.93928552606164 -2.14643619511202 0.00746967159421694 305.941917876057 112.594173850167 2.71720913626654 0.00694640182343717 -450.364093799304 439.126102182769 -1.02559171855345 0.305868508297402 MGST1 other 1 1 1 2.71720913626654 -1.02559171855345 0.0235204254167782 54.0955325137211 19.887249957877 2.72011125863557 0.0068825661067033 -1.81302582363269 54.2722101656047 -0.0334061542380616 0.973371529100535 CRY1 other 1 1 1 2.72011125863557 -0.0334061542380616 1.09798120067685e-08 557.697972500305 104.049155727114 5.3599471192535 1.61189625707131e-07 -720.354830353287 345.130312425727 -2.08719664549404 0.0376738623752036 NFIX other 0.000127113283602358 1 0.00199036949823166 5.3599471192535 -2.08719664549404 0.00122687892591015 197.386221572651 55.6602686192185 3.54626785801204 0.000449285786313212 444.546847501979 315.178980308413 1.41045842291569 0.159378721173946 ST3GAL1 other 1 1 1 3.54626785801204 1.41045842291569 0.00860342730461213 -1.4550608565195 7.9838956797341 -0.182249482569387 0.855502701810739 -69.3825354062515 22.8543323253195 -3.03585921560198 0.00259607545809963 MMP25 other 1 1 1 -0.182249482569387 -3.03585921560198 0.0734880188958883 -410.508151937759 330.40817116156 -1.24242736036039 0.214991471090813 -2073.83730886571 945.811224199116 -2.1926545760987 0.0290541760297534 IL32 other 1 1 1 -1.24242736036039 -2.1926545760987 0.0708748074619809 58.634141625562 25.5092677590553 2.29854271707772 0.0221833620189082 59.3246016888989 73.4082603764443 0.808146132120239 0.419614418124133 MAPK8IP2 other 1 1 1 2.29854271707772 0.808146132120239 6.33873366869169e-10 164.415013013456 35.4852983277444 4.63332762472247 5.2499574777072e-06 -58.0050153660402 65.5978829754105 -0.884251331522138 0.377226517091685 RHOBTB2 other 7.72311310193396e-06 1 0.0600542635874927 4.63332762472247 -0.884251331522138 0.000407336216785968 100.408760324558 26.4335871591199 3.79852948902229 0.000174267303905335 -54.0915443209555 90.5628567444131 -0.597281780472241 0.550742976500397 HEATR5B other 1 1 1 3.79852948902229 -0.597281780472241 3.29660401310073e-29 575.317723580485 45.1250070299788 12.749421251021 2.5466858286029e-30 -146.737870433676 323.47544395159 -0.453629087392599 0.650407181097146 SEC62 other 4.97325681416376e-25 1 3.87019845372783e-26 12.749421251021 -0.453629087392599 4.75334866030342e-06 2190.9041921351 476.841980081286 4.59461264664998 6.32329518815201e-06 -3089.2823262118 2229.31555847294 -1.38575371910468 0.166821431688345 RPS20 essential 0.0467016505874811 1 0.0719654225363581 4.59461264664998 -1.38575371910468 7.16247353581256e-14 2341.50327955611 438.732820253919 5.33696858648721 1.79688174169588e-07 -2348.07111416819 799.376095611924 -2.93737969781387 0.00355093489815217 CSDE1 other 9.65573057362892e-10 1 0.00221411768211766 5.33696858648721 -2.93737969781387 8.06891754815104e-20 655.48150367648 95.8911326862218 6.83568423183996 4.19691541154430e-11 -687.620002814439 215.709079150271 -3.18771933718848 0.00157703605597079 UBE3C other 1.16967028777997e-15 1 5.73970151682799e-07 6.83568423183996 -3.18771933718848 0.0047158451200164 27.0755400066631 31.4961099614901 0.859647113239318 0.390629150936904 -208.309118993401 72.1302582716492 -2.88795748115708 0.00414251169930299 REV3L essential 1 1 1 0.859647113239318 -2.88795748115708 0.959771480133038 -2.79212484427757 10.5190052015294 -0.265436207206324 0.790844361894194 -3.77253199726066 20.397732394976 -0.184948597432813 0.853386514984005 PAX7 other 1 1 1 -0.265436207206324 -0.184948597432813 0.0310657187064083 0.834358783238741 1.13871190612224 0.732721576680493 0.46426462608404 -5.24751762628861 2.39781845845209 -2.18845492985159 0.0293590486566821 MASP2 other 1 1 1 0.732721576680493 -2.18845492985159 2.6970372583788e-08 20.1947220797118 9.14915350088932 2.20727765445719 0.0280040544711497 -91.115585730317 18.3347139525892 -4.96956679912913 1.09522327338142e-06 FAM76A other 0.000306734047395421 0.0163998732956134 1 2.20727765445719 -4.96956679912913 0.824993101643925 15.7511858250593 25.6936117028849 0.613038992228981 0.540288742692214 -7.44031314012344 87.1899570452107 -0.0853345200785614 0.9320491486765 TRAF3IP3 other 1 1 1 0.613038992228981 -0.0853345200785614 6.78134130921946e-19 122.362691151802 12.845697134539 9.52557808815205 4.22793158761196e-19 -0.863870998298437 41.8835769952409 -0.0206255305843767 0.983557228893433 POMT2 other 9.75156880265759e-15 1 6.25099685228429e-15 9.52557808815205 -0.0206255305843767 4.18929719443829e-12 192.551882477129 39.6396353805344 4.85755937532371 1.86575267176161e-06 -408.68974727822 89.8876486256397 -4.54667302490372 7.74901442445649e-06 VTA1 other 5.44105919613645e-08 0.11434445684728 0.0218983391084661 4.85755937532371 -4.54667302490372 0.000734794821164356 19.1039281672308 6.67833637723519 2.86058190065889 0.00450938609386735 74.2805154382778 23.0424168724838 3.22364254797336 0.00139749362341284 MLXIPL other 1 1 1 2.86058190065889 3.22364254797336 9.95404363156719e-09 516.44782992064 93.7083881000943 5.51122306542077 7.40557527382473e-08 -444.442965105084 317.391005806381 -1.40030107020805 0.162404266044862 BAZ1B other 0.000115546538475232 1 0.00092747424729381 5.51122306542077 -1.40030107020805 3.45359108746802e-08 271.883015111774 52.4314843449316 5.18549147537258 3.84128185791985e-07 -82.7452804054917 123.886862862671 -0.667910047066208 0.504675464290734 RANBP9 other 0.00039042847243826 1 0.00466715745737262 5.18549147537258 -0.667910047066208 0.837986683884313 -17.1654650201895 29.6953137200758 -0.578052994556666 0.563634892157488 -5.16197597036682 68.9335139635963 -0.0748834010274429 0.940354273800594 ETV7 other 1 1 1 -0.578052994556666 -0.0748834010274429 0.000682470148504093 50.2930179884451 13.0902606063127 3.84201808512441 0.000147150398963611 11.719909057373 44.1654183099456 0.265363931914436 0.790899984236243 SPRTN essential 1 1 1 3.84201808512441 0.265363931914436 1.62382988307642e-06 149.006215443175 28.5101889068548 5.22641978732555 3.12423327849921e-07 50.1661215962733 91.9276112207904 0.5457133164897 0.585643220707884 METTL13 other 0.0165366382202063 1 0.00381156459976903 5.22641978732555 0.5457133164897 4.71325994714482e-07 51.2337034940986 9.31690773103349 5.4990029925321 7.88938359466934e-08 15.3835143816206 45.7959276585676 0.335914461572056 0.73715829842729 DYRK4 other 0.00499228493601579 1 0.000986094055497721 5.4990029925321 0.335914461572056 5.92541944232592e-17 827.725634123821 288.389251815088 2.87016811103124 0.00437742371884323 -2362.57475569451 405.303449945812 -5.82915037118581 1.36740877466164e-08 UQCRC1 essential 8.34595328451606e-13 0.000207654696520117 1 2.87016811103124 -5.82915037118581 0.000123512928664822 74.7622416242879 20.2789360825841 3.68669447548064 0.00026678569008838 -129.230061970664 83.1209928679931 -1.55472230915117 0.121000640183022 STARD3NL other 1 1 1 3.68669447548064 -1.55472230915117 8.69028349569575e-16 6098.15142633686 725.612023174969 8.40414881723425 1.43237208936416e-15 -5221.24813092325 3840.69303986408 -1.35945468089479 0.174959741296869 CD9 other 1.20855772574641e-11 1 2.07335859935462e-11 8.40414881723425 -1.35945468089479 0.326669167527099 28.1094344016655 25.9813085563428 1.08190987920057 0.280107193011106 53.698546730757 37.0527450021982 1.44924611462852 0.148248121961062 HHATL other 1 1 1 1.08190987920057 1.44924611462852 9.10358864585032e-32 1547.36722735019 116.636067260744 13.2666272422491 2.73173374441827e-32 -83.1137201700661 644.780078462323 -0.128902431924194 0.897516084199194 NCAPD2 essential 1.37919367984632e-27 1 4.15797193237904e-28 13.2666272422491 -0.128902431924194 0.107974663324571 9.92356407864942 5.28599951076093 1.87732973838677 0.0613852915329755 36.2835349040518 29.2374387563547 1.24099567018899 0.215519187191025 IFFO1 other 1 1 1 1.87732973838677 1.24099567018899 0.0145130392321944 10.940053578617 4.61083283482935 2.3726849292774 0.0182500424854104 -12.1680993484355 11.0612521610565 -1.10006527030239 0.272130543626555 GIPR other 1 1 1 2.3726849292774 -1.10006527030239 4.46863314246054e-10 7.12311876577527 4.92700920633684 1.4457287306494 0.149238092103752 -33.8744550325969 6.9767625882198 -4.85532574804732 1.88798904247184e-06 PHF7 other 5.47854423265662e-06 0.0281857884150622 1 1.4457287306494 -4.85532574804732 0.712493604631435 -12.0535856493041 19.1353031976377 -0.629913491561095 0.529203522573755 3.13211494594188 27.0960458713611 0.115593063313062 0.908048019040133 SEMA3G other 1 1 1 -0.629913491561095 0.115593063313062 6.01401419853703e-14 115.676582936276 75.0260335287061 1.54181925254008 0.124112013202982 -637.407655864052 106.238653500461 -5.99977159783267 5.37548064069281e-09 NISCH other 8.11470935808601e-10 8.18148153513446e-05 1 1.54181925254008 -5.99977159783267 0.549749914809675 -122.035124718281 113.161480913715 -1.07841576243892 0.281663024291897 -120.386841746754 163.077953963629 -0.738216532773053 0.4609256091979 STAB1 other 1 1 1 -1.07841576243892 -0.738216532773053 0.000515573768654571 64.8714062499998 23.4819508032342 2.76260719535555 0.0060668348230175 -115.446768292683 54.3397441727492 -2.12453647050069 0.0343940178907514 FUZ other 1 1 1 2.76260719535555 -2.12453647050069 0.00592607990771941 118.340954437822 36.831255195897 3.21305787186436 0.00144964964461141 127.58188729718 119.790675270966 1.06504022127423 0.28767600941595 PRSS3 other 1 1 1 3.21305787186436 1.06504022127423 0.0013560652386219 25.3863315505042 8.68518450705579 2.92294671804387 0.00371438335878372 -33.7701340266321 24.9597912247709 -1.35298143011379 0.177016663618962 ZNF200 other 1 1 1 2.92294671804387 -1.35298143011379 0.694403284046733 -35.6068774788639 43.4385487093108 -0.819706885631558 0.412995243340984 28.9203374818018 240.062736779722 0.120469914947019 0.904186751011764 CD4 other 1 1 1 -0.819706885631558 0.120469914947019 0.00218966475633772 37.5197341253004 10.9153544482481 3.43733538871222 0.00066535767592867 -21.6382060057512 61.2975598771476 -0.353002730436879 0.724319536485404 LRRC23 other 1 1 1 3.43733538871222 -0.353002730436879 0.0953319441093883 26.2005777580741 13.5553473376015 1.93285919611928 0.054135656579371 -4.53540590982645 29.5648420589492 -0.153405382676604 0.87817529209507 HFE other 1 1 1 1.93285919611928 -0.153405382676604 1.00744570223352e-09 136.880177207827 20.8725882393341 6.55789189334355 2.19028408963295e-10 2.52369649418239 64.9547121184905 0.0388531703377987 0.969031680773856 SCMH1 other 1.21739738657899e-05 1 2.95600740736862e-06 6.55789189334355 0.0388531703377987 0.528785463235938 -27.9036366236051 46.7644525005667 -0.596684770836716 0.551141077146043 -115.093569928812 107.096782457339 -1.07466879291782 0.283335220141759 FYN other 1 1 1 -0.596684770836716 -1.07466879291782 1.1291089237043e-05 168.335230888905 64.3012304085734 2.61791617079943 0.00926872251781721 -492.274590253111 144.619236149392 -3.40393576511903 0.000748999835783204 HIVEP2 other 0.107220183394961 1 1 2.61791617079943 -3.40393576511903 0.536953911483671 12.8920168151482 19.8599500603054 0.649146487075808 0.516709323795256 -59.342976886463 64.0359758391188 -0.926713087586167 0.354773914465463 FMO1 other 1 1 1 0.649146487075808 -0.926713087586167 8.94797038986202e-09 247.362378065259 52.5358951036578 4.70844510362281 3.72391629552928e-06 -270.763884414492 102.235715351707 -2.64842754298753 0.00848760934358983 ELOA other 0.000104136479397214 1 0.0429814418829989 4.70844510362281 -2.64842754298753 4.3604963040853e-07 176.513062107496 82.4944287261698 2.1396967629585 0.0331353731984073 -690.976438599943 160.412996025294 -4.30748415478126 2.19931801327915e-05 LYPLA2 other 0.00462953892604736 0.320748539056632 1 2.1396967629585 -4.30748415478126 5.96044548102451e-06 41.9429033774165 11.1100152538834 3.7752336445043 0.000190511798908945 -45.136451492473 23.3946791161293 -1.92934689415569 0.0545717532699679 CLCN6 other 0.0580487785396977 1 1 3.7752336445043 -1.92934689415569 0.0182563999286153 725.373941740572 263.424306105026 2.75363330159583 0.00623488994029582 -255.937479143611 610.374898014121 -0.419311934314982 0.675273076279245 MRC2 other 1 1 1 2.75363330159583 -0.419311934314982 0.0652070221607443 1022.2229056933 493.796171346772 2.07013129102501 0.0392444635889646 -1142.12438083675 1177.3891413009 -0.970048338967029 0.332757316247746 NME1-NME2 other 1 1 1 2.07013129102501 -0.970048338967029 1.30241208373173e-12 539.098741563928 72.9358033458987 7.39141432373408 1.32675593537599e-12 -400.314246519845 357.037888017072 -1.12120942890157 0.263055457737415 TSPAN9 other 1.71189044285698e-08 1 1.85958111902299e-08 7.39141432373408 -1.12120942890157 1.48430014690939e-14 220.795917603697 29.7649846308463 7.41797519273299 1.07736279061492e-12 -142.321545893312 88.9552471028387 -1.59992300093077 0.110602454376458 BTBD7 other 2.02517912044317e-10 1 1.51197094034898e-08 7.41797519273299 -1.59992300093077 1.89209772217848e-08 45.7930738780197 18.0610838923919 2.53545546606478 0.0117103343547532 -121.46999434692 32.1454868544455 -3.77875733837647 0.000188255186979023 APBA3 other 0.00021700468775665 1 1 2.53545546606478 -3.77875733837647 0.000128591564049209 42.9495613872473 10.3142058313294 4.16411714964887 4.03623429255377e-05 -11.4490866826239 24.2908622432351 -0.471333070352922 0.637728139423464 MKS1 other 1 1 0.433975911135381 4.16411714964887 -0.471333070352922 3.72458087546403e-05 22.8582123579721 31.7741891317091 0.71939561583212 0.472422236764505 -158.790778350134 45.5333654372473 -3.48734992077349 0.000556053599242544 ABHD5 other 0.336888340185721 1 1 0.71939561583212 -3.48734992077349 1.13810086292205e-06 126.781003530583 32.8190492839695 3.86303096209765 0.000135642453334264 -230.307286206355 88.0946547472707 -2.61431623595177 0.00936484716720102 AKAP8L other 0.0117372341993151 1 1 3.86303096209765 -2.61431623595177 0.0951184885502865 36.9992517019436 17.5686151935904 2.10598566217342 0.0359891348805976 -17.32282158254 41.8729924773558 -0.413699154458758 0.679373307351547 MBTD1 other 1 1 1 2.10598566217342 -0.413699154458758 3.47895386281449e-10 165.806135622425 25.866577760559 6.41005304827157 5.24816593048106e-10 -117.405407512344 61.2021059238235 -1.91832300114762 0.0559652726569075 UTP18 essential 4.28050483280695e-06 1 7.02991826387938e-06 6.41005304827157 -1.91832300114762 7.26598152460133e-19 271.784614819138 28.5621945486786 9.51553685260197 4.62603071225801e-19 -100.312458437939 137.063411121859 -0.731868976679375 0.464785861375323 RNF216 other 1.04448484416144e-14 1 6.83819859885979e-15 9.51553685260197 -0.731868976679375 5.37251419441418e-12 181.899840121685 26.5748990547556 6.84479891144247 3.9518572023499e-11 -140.401428727395 55.6200294381343 -2.52429619591558 0.0120794235163195 TTC19 other 6.96009213886357e-08 1 5.40851176713607e-07 6.84479891144247 -2.52429619591558 0.48903839547468 10.6457497417591 10.0018321677159 1.06437996191555 0.287959095515941 -7.3023648208765 29.5049278606478 -0.247496447216061 0.804682763445912 DPF1 other 1 1 1 1.06437996191555 -0.247496447216061 6.29316471476516e-06 319.342798147477 65.0952817900341 4.90577487900771 1.48818624944035e-06 134.393923525373 233.756311308726 0.574931743117199 0.565743992401541 SYT7 other 0.0611409104919035 1 0.0175858969096367 4.90577487900771 0.574931743117199 2.99266863999389e-17 138.544389125773 27.8877237452674 4.96793465079001 1.10381213772074e-06 -162.747424395534 39.9639440440996 -4.07235642748234 5.87195689294066e-05 LARS2 essential 4.22983785576736e-13 0.844915877325232 0.0131331568146014 4.96793465079001 -4.07235642748234 1.87924538838746e-09 145.522025766802 45.1733112508062 3.22141595861439 0.00140719258118801 -341.275600102894 93.5465104811037 -3.64819166794929 0.000308380304927876 PIK3C2A other 2.24682578635604e-05 1 1 3.22141595861439 -3.64819166794929 4.02505534590641e-20 684.966509981755 67.7920163038901 10.1039406603761 5.34537046166238e-21 191.442678226108 284.066376624734 0.673936424651248 0.500841303266077 PLAUR other 5.84639288992906e-16 1 7.96887828424627e-17 10.1039406603761 0.673936424651248 7.58553856834405e-05 399.394448239021 102.159408587288 3.90952193010952 0.000112991050076183 -541.175458899752 411.444376202876 -1.31530649147312 0.189351538092077 ANLN essential 0.662445083173486 1 1 3.90952193010952 -1.31530649147312 2.9273411705612e-14 353.286825948038 46.2271013702292 7.64241787774215 2.50199685783476e-13 -150.439318261494 124.58145336823 -1.20755790042708 0.228109116742753 WIZ other 3.9721092343345e-10 1 3.53832395634992e-09 7.64241787774215 -1.20755790042708 0.850097612372297 66.9749362404352 849.053648149825 0.078881866165207 0.93717589063762 1170.54335620931 2054.37083494965 0.5697819187732 0.569225397914275 DCN other 1 1 1 0.078881866165207 0.5697819187732 0.0015354074451188 34.9298998250858 15.9411764624514 2.19117452889135 0.0291598357452656 -87.7309206331109 38.2424127943039 -2.29407388872122 0.022433726225276 QPCTL other 1 1 1 2.19117452889135 -2.29407388872122 5.32618122606123e-06 182.4048600552 51.3915197168949 3.54931827391036 0.000444119826316223 -305.636237505095 118.287004158951 -2.58385305873829 0.010213314896235 PPP5C other 0.0520687476659745 1 1 3.54931827391036 -2.58385305873829 0.0152964648471925 86.6594833280142 30.4723474833224 2.8438729039646 0.00474458793481618 -85.7374264362106 129.658227770401 -0.661257121206644 0.50892474112547 CEP68 other 1 1 1 2.8438729039646 -0.661257121206644 2.17954633256602e-08 128.881983473995 22.3545197533628 5.76536579161391 1.92359676513662e-08 -77.5798132621235 76.5654028286418 -1.0132489400696 0.311709172639793 MAP4K3 other 0.000249056759422319 1 0.000246508925452258 5.76536579161391 -1.0132489400696 0.0787698585281285 3.99263005191739 2.76024144343642 1.44647855404514 0.149027947039871 -18.7928907353968 13.0308975577572 -1.44217930131831 0.150235937890054 ZBTB32 other 1 1 1 1.44647855404514 -1.44217930131831 0.285236670788556 28.3916915906674 34.0402459511466 0.834062469214065 0.40486990461144 -183.549118406614 157.533986619289 -1.1651398047216 0.244832918323906 TYROBP other 1 1 1 0.834062469214065 -1.1651398047216 0.000278905990292057 129.548977185514 65.9593826662052 1.96407200839205 0.0503897655146094 -595.988211045405 203.192774880434 -2.93311714157212 0.00359873536355867 TMEM159 other 1 1 1 1.96407200839205 -2.93311714157212 0.00473760977357735 40.2730602049445 33.1867305208691 1.21352900912066 0.22582537678689 -241.264299903625 81.5621295945944 -2.95804316418455 0.00332733562364442 BRCA1 ts 1 1 1 1.21352900912066 -2.95804316418455 5.20403652235506e-09 325.270018061408 65.1981623934355 4.98894456715789 9.98062809638992e-07 -413.750150511739 156.408471203662 -2.6453180401782 0.00856428980638982 ERCC1 ts 6.12150816124626e-05 1 0.0119009009421353 4.98894456715789 -2.6453180401782 0.835532389819274 1832.50869857303 9853.81552205227 0.185969454621104 0.852586544405406 8247.33573913588 14177.5691463261 0.581717193830302 0.561166747700137 LTF other 1 1 1 0.185969454621104 0.581717193830302 1.0484929220097e-12 534.08801157204 97.5324241910035 5.47600468256694 8.81021383227655e-08 -163.088964887811 178.923317648982 -0.911502016790033 0.362717052790896 EXTL3 other 1.38044578111797e-08 1 0.00109951468626811 5.47600468256694 -0.911502016790033 7.0271381740354e-05 320.880344335541 76.3220234626257 4.20429555949435 3.40819690190673e-05 -35.114990992745 205.280362222893 -0.171058695593187 0.864286404690431 ELOVL5 other 0.616209746481164 1 0.368596494941213 4.20429555949435 -0.171058695593187 0.0676540635348077 -62.1192311678782 26.9974647937622 -2.30092831465534 0.0220443224488097 -72.1507410849764 57.8368653708798 -1.24748705902902 0.213139748751003 ALOX5 other 1 1 1 -2.30092831465534 -1.24748705902902 0.0462721230846126 114.957321178847 60.4007062466128 1.90324465262844 0.0579057738723942 -203.057095008719 168.213964522037 -1.20713577844553 0.228271386657044 CALCOCO1 other 1 1 1 1.90324465262844 -1.20713577844553 0.00268966683338416 90.6924731987501 31.1057229861134 2.91562016543509 0.00380037131991949 -88.8712848968481 92.9621603659297 -0.955994186742449 0.339796818612168 UBR7 other 1 1 1 2.91562016543509 -0.955994186742449 1.43117214323416e-17 290.737312420501 31.789217155492 9.14578396185111 7.35572009169523e-18 3.18460799016281 96.489191167368 0.0330048158932005 0.973691518442869 MAP4K5 other 2.03212132617818e-13 1 1.07945192345627e-13 9.14578396185111 0.0330048158932005 0.0470799699350912 96.1688554600448 38.7468327190718 2.48197978289743 0.0135798549912516 37.8094209819639 134.732710036754 0.280625402485036 0.77917963987054 EHD3 other 1 1 1 2.48197978289743 0.280625402485036 2.75767760092213e-14 401.485577767291 58.365068074235 6.87886763460359 3.18002005422621e-11 -484.891821593976 179.546494723567 -2.70064766421937 0.00728879824296677 PSMC4 essential 3.74437464653207e-10 1 4.36044349835498e-07 6.87886763460359 -2.70064766421937 4.13961884146131e-10 265.911051913912 61.5239794689856 4.32207172242423 2.06811669281398e-05 -211.340948752809 114.00782748779 -1.85374068965083 0.0646992783087462 MAN2B2 other 5.07931231847303e-06 1 0.227099894037903 4.32207172242423 -1.85374068965083 0.00115431796979078 519.298119708362 154.024180229007 3.37153633238792 0.000839127043132372 -482.744695095564 371.325816642877 -1.30005691352143 0.194517086228042 SLC25A39 other 1 1 1 3.37153633238792 -1.30005691352143 5.35334383029571e-05 399.956620058965 226.614179293159 1.76492318930124 0.0785395350018702 -2870.20680164342 820.565559723079 -3.4978397126636 0.000536069178515772 MVP other 0.475858733074986 1 1 1.76492318930124 -3.4978397126636 1.49439121462785e-09 42.8698533625774 74.4784738642228 0.575600588174387 0.565290991174976 -884.520671294602 165.529541534968 -5.34358195577885 1.73771554382891e-07 NUB1 other 1.79341889667488e-05 0.00262238652719221 1 0.575600588174387 -5.34358195577885 9.20854837916625e-09 144.781496176328 37.7756575389595 3.83266647382667 0.00015303976927116 -301.652716205449 79.2509218184571 -3.80629914812165 0.000169495357618742 PGM3 other 0.000107086209101324 1 1 3.83266647382667 -3.80629914812165 0.0956886994110956 4.40214901685924 4.97457454045333 0.884929752496596 0.376869500105044 -17.6602646741013 10.4363403225731 -1.69218941968607 0.0915987166067648 RWDD2A other 1 1 1 0.884929752496596 -1.69218941968607 9.32188810959005e-05 142.950727457314 48.9675628241992 2.91929430857174 0.00376022979592179 -279.693110876398 120.892080899535 -2.31357677686788 0.0213324095051561 CLK1 other 0.805970445955155 1 1 2.91929430857174 -2.31357677686788 0.000213567989636863 49.4183138597863 14.0463077009779 3.51824229625454 0.000497309091952563 -64.9347724504653 38.3323066393239 -1.69399595650346 0.0912390637494025 POLR3B essential 1 1 1 3.51824229625454 -1.69399595650346 1.82276156749835e-21 161.197799404524 15.6873717834942 10.2756409186484 1.41186950518591e-21 -4.4174882732884 50.965251927798 -0.0866764728161576 0.930983228788993 ANGEL1 other 2.67089252485533e-17 1 2.11003897550035e-17 10.2756409186484 -0.0866764728161576 5.5578171200019e-08 56.2554040993396 29.6335442138373 1.89836908111286 0.0585498321577758 -196.86152258231 42.2530718274656 -4.6591055766588 4.67050363827938e-06 RNF14 other 0.000621308375845013 0.0692915919775129 1 1.89836908111286 -4.6591055766588 3.48780689853729e-07 136.552296540951 24.9982627381958 5.4624714513584 9.52635295908831e-08 -52.1805432946134 142.485745519936 -0.366215884292177 0.714449050320623 DDX11 essential 0.003736487530403 1 0.00118765042340954 5.4624714513584 -0.366215884292177 7.63805715876757e-23 181.714032453843 17.5508405283118 10.3535800556512 7.39365006661264e-22 -82.2926022450119 67.8882784034174 -1.21217689092068 0.22633890113746 HEBP1 other 1.12837018406473e-18 1 1.10542462145926e-17 10.3535800556512 -1.21217689092068 0.00338601847421453 -42.1467731144233 13.7844689788718 -3.05755507731374 0.00241970760506945 47.8543288628989 64.2680525652853 0.74460524246144 0.457056865745328 CD6 other 1 1 1 -3.05755507731374 0.74460524246144 2.73203494757951e-07 39.4572349455369 121.133815905099 0.325732617689921 0.744840895166619 -1014.28958241071 223.637128367184 -4.53542571314621 8.15574314577987e-06 TACC3 essential 0.00294267484203789 0.120289055657107 1 0.325732617689921 -4.53542571314621 3.65905776351524e-05 17.7294013454052 28.2853639288955 0.626804781086567 0.53124121425996 -255.170717941691 61.2008903710858 -4.16939551687055 3.95177943594042e-05 UFL1 essential 0.331181318175764 0.572099108941094 1 0.626804781086567 -4.16939551687055 0.0157626337898345 45.6887361511939 29.5865063832819 1.54424235018876 0.123536833744239 -271.532487121228 131.168977881961 -2.07009684382522 0.0392605462725055 POLA2 essential 1 1 1 1.54424235018876 -2.07009684382522 2.25421996560203e-23 192.317750594803 17.4270738770721 11.0355732667103 3.27928721814966e-24 0.427688861148725 84.3734985469358 0.00506899522378829 0.995958702838368 ZC3H3 other 3.33872519105317e-19 1 4.93172004737527e-20 11.0355732667103 0.00506899522378829 1.47934972383515e-16 2794.82806170579 358.180811093185 7.80284140062066 8.92203779936721e-14 -4340.80456218587 1546.31215279653 -2.80719811606955 0.00530791799706724 CAPN1 other 2.07523179259595e-12 1 1.27058740300788e-09 7.80284140062066 -2.80719811606955 1.17709940279994e-06 110.919079423785 21.0012755963766 5.28154011001706 2.37162562545573e-07 1.09886685478356 86.4902590178 0.0127050938135983 0.989870991738324 ACPP other 0.0121276551470478 1 0.00290856166705891 5.28154011001706 0.0127050938135983 0.0225027351076177 281.945992143589 109.823950734022 2.56725413954941 0.0107062673039064 -424.679320988128 460.67155393416 -0.921870077197831 0.357293026262388 MDH1 other 1 1 1 2.56725413954941 -0.921870077197831 1.5009120334291e-12 164.062604934292 37.2226241250168 4.40760448224357 1.43247939813597e-05 -214.819349396573 71.7128572550482 -2.99554860340544 0.00295549520929577 SLC30A9 other 1.97009713507904e-08 1 0.158933589223186 4.40760448224357 -2.99554860340544 0.0702933762094386 28.9279463312057 16.9213517544562 1.70955292171547 0.0883333941842073 -111.687851660445 70.0712054196381 -1.59391937089674 0.111956952980875 MTMR11 other 1 1 1 1.70955292171547 -1.59391937089674 3.04225803001598e-11 102.324300565263 29.4095730477437 3.47928548296669 0.00057242450592251 -216.578424163433 53.7883392797994 -4.0264939773809 7.07484598990991e-05 COX15 essential 3.86701418195331e-07 1 1 3.47928548296669 -4.0264939773809 0.0542696866259778 62.0998340075309 59.1827172683716 1.0492900102226 0.294841451325988 -312.807482392263 175.722213526665 -1.78012486932846 0.076010292011855 CCDC88C other 1 1 1 1.0492900102226 -1.78012486932846 0.00417329505051991 25.4802133516861 9.35467626402959 2.72379424284966 0.00681257787023425 -33.8158772862834 25.015830462775 -1.35177911988984 0.177412766683814 YAF2 other 1 1 1 2.72379424284966 -1.35177911988984 2.81968637619342e-10 241.223142241212 52.9857786605684 4.55260162894857 7.62138481059554e-06 -233.749289010349 105.365039690398 -2.21847103837469 0.0272469385594795 ZMYND11 other 3.48146676868602e-06 1 0.0862664546711309 4.55260162894857 -2.21847103837469 0.327394870719183 -3.88328237616944 4.79959647760155 -0.809085179200313 0.419067305658362 9.4640278039645 12.2978896410287 0.769565192095252 0.442125538576758 DPEP1 other 1 1 1 -0.809085179200313 0.769565192095252 1.79068336984114e-05 200.437246284213 50.6419094706373 3.95793224188018 9.36659795553674e-05 -212.407158576804 153.856205892274 -1.38055632754604 0.168403638685596 BID other 0.16705285157248 1 0.973845189437155 3.95793224188018 -1.38055632754604 0.000298693633692914 305.355659676425 169.302588792223 1.80360892207722 0.0722330431314894 -708.072723503913 248.592345395938 -2.84832874631016 0.00467940004300687 MATR3 other 1 1 1 1.80360892207722 -2.84832874631016 0.00243234378556394 135.636002006261 43.8328325991498 3.0943928093046 0.00214674602902569 -150.931937021856 104.550678518254 -1.44362465323938 0.149825909316312 XYLT2 other 1 1 1 3.0943928093046 -1.44362465323938 1.44234535259346e-23 491.195077787624 47.3773589896003 10.3677175820511 6.6189870645832e-22 -396.63114187486 189.996420299972 -2.0875716566062 0.0376271658395476 NUDCD3 essential 2.13726734347299e-19 1 9.89737135767125e-18 10.3677175820511 -2.0875716566062 0.0713613700591099 -5.61839971616699 11.1823489982899 -0.502434659929342 0.615725554571371 -38.0758388525833 16.79612956187 -2.26694124454849 0.0240960433782627 ISL1 other 1 1 1 -0.502434659929342 -2.26694124454849 0.00298800042426145 3.34681599072208 42.2608647620809 0.0791942145425536 0.936927646343753 -174.313643408869 60.9651274547162 -2.85923528230702 0.00452540328433523 CHDH other 1 1 1 0.0791942145425536 -2.85923528230702 0.256414135875494 -18.7019451997489 28.375063208686 -0.659097922080542 0.510311370156368 87.589506080617 65.7223463035428 1.33272031518898 0.1835807186122 IL20RA other 1 1 1 -0.659097922080542 1.33272031518898 0.278715403078789 -416.498819201994 356.489896360779 -1.16833274506182 0.243542247239024 -1061.38431090557 757.537549413761 -1.4010979544538 0.1621538151926 CLCA4 other 1 1 1 -1.16833274506182 -1.4010979544538 1.10645319018912e-13 165.491609582835 38.0998592471299 4.34362784674334 1.88374812236028e-05 -188.684652071114 54.9624998940428 -3.43297070611529 0.00067551388304843 GLT8D1 other 1.48585598910496e-09 1 0.207400668271867 4.34362784674334 -3.43297070611529 1.50926532565934e-12 1065.62397058445 138.645587806567 7.68595659943512 1.87860837045185e-13 973.883291212564 562.352049958396 1.73180357621994 0.0842722302420136 ATP2C1 other 1.98091073992789e-08 1 2.66273950427846e-09 7.68595659943512 1.73180357621994 0.292963198346466 -40.470944440548 25.8357673508982 -1.566469611329 0.118233244997491 -6.52370272267744 67.1250540221242 -0.097187299402802 0.922638877910644 IGF1 other 1 1 1 -1.566469611329 -0.097187299402802 2.23603389884488e-53 1134.95382456261 60.2869915952816 18.8258494001787 1.34479942372468e-53 209.407554415209 252.830662748662 0.828252206985593 0.408150816750162 RALBP1 other 3.4291815872685e-49 1 2.06292231599366e-49 18.8258494001787 0.828252206985593 4.42107787808051e-06 57.2290890812737 19.0323482267622 3.00693789328641 0.00284862008648965 -109.330504561272 39.8393914315026 -2.74428149208174 0.00640768608423759 RUFY3 other 0.0435034063203123 1 1 3.00693789328641 -2.74428149208174 0.000552831539904331 374.062089356111 111.815043933423 3.3453645967249 0.00092140511701593 -407.183333045163 302.896158135181 -1.34430009133176 0.179821745878945 CNTN1 other 1 1 1 3.3453645967249 -1.34430009133176 0.966252642332406 5.72865279811041 21.8679652290073 0.261965516138259 0.793516574239962 4.3837513993627 38.3674407134044 0.114257071043864 0.909105665750905 SLC11A1 other 1 1 1 0.261965516138259 0.114257071043864 7.98617162353359e-13 416.449777711112 53.509976593699 7.78265669733352 1.01256197723273e-13 -26.0696246505252 324.05320544467 -0.0804485936645869 0.935931244781787 WWTR1 other 1.0543343777389e-08 1 1.44138197459079e-09 7.78265669733352 -0.0804485936645869 4.26523372333751e-13 315.120934600079 40.3491873568148 7.8098458790114 8.92054970894172e-14 -64.3109179333219 153.268007647024 -0.41959779422089 0.675069934577439 AGPS other 5.66337733784754e-09 1 1.27046468954748e-09 7.8098458790114 -0.41959779422089 0.341914186414442 223.272660830032 170.936462080618 1.30617340567591 0.192431685016083 -421.087630031308 598.33927949488 -0.70376063290846 0.482093618038877 ATP1A2 other 1 1 1 1.30617340567591 -0.70376063290846 5.60970957348697e-10 98.3631247716482 15.314531333248 6.42286222354717 4.87163381947998e-10 -57.0271850686515 53.241031769584 -1.07111344715206 0.284930677646221 TTC27 essential 6.85113830209963e-06 1 6.53286095192265e-06 6.42286222354717 -1.07111344715206 0.972690781344234 -0.359321092966012 1.54438779113811 -0.232662479610264 0.816173650846412 -0.133582871370232 3.9655903970315 -0.0336854939608052 0.973149146643543 ZNF582 other 1 1 1 -0.232662479610264 -0.0336854939608052 0.0695371929317256 0.828917471839013 15.9047613621724 0.0521175673726545 0.95846763574554 -51.9613561043522 29.4517352161132 -1.76428844423142 0.0786404542721167 VSIG2 other 1 1 1 0.0521175673726545 -1.76428844423142 0.987809023375533 -3.85330427247439 28.4891233027023 -0.135255277304686 0.892496430768082 5.25890968970005 90.5285293669308 0.0580911865737331 0.953712827595439 MARCO other 1 1 1 -0.135255277304686 0.0580911865737331 0.296242278158234 126.02510401029 80.6952027245635 1.56174220716008 0.119337116018162 117.037094760427 369.855670422786 0.316439909185767 0.751874947819526 CYP24A1 other 1 1 1 1.56174220716008 0.316439909185767 3.85549849711132e-07 107.238091473298 30.2596032078272 3.54393581226995 0.000455120681498139 -158.186084698399 72.140619044127 -2.19274642766289 0.029070926701242 PRDM11 other 0.00411073249762009 1 1 3.54393581226995 -2.19274642766289 0.0825630435237366 20.5381863462071 9.7277439613278 2.11130005352276 0.0355493059429963 38.0147881627801 23.1914961492763 1.6391692850729 0.102195697460521 SYT13 other 1 1 1 2.11130005352276 1.6391692850729 6.21115514024934e-09 465.613379744054 73.9169146992885 6.29914521782029 1.12136845036399e-09 143.995610191545 372.690972123671 0.386367314912481 0.699510935403886 SNAI2 other 7.27947382437222e-05 1 1.49063508106886e-05 6.29914521782029 0.386367314912481 1.35667084753055e-07 4024.40898840454 4637.17401732526 0.867858090588939 0.386122376908742 -34124.6255792901 6713.63243371012 -5.08288559378756 6.33608959663678e-07 CD74 other 0.00148582591221546 0.00951427213830978 1 0.867858090588939 -5.08288559378756 0.89563201588728 -5.53578458942634 27.1077871416622 -0.204213813562021 0.838317461120953 -46.7010083560984 101.355994818418 -0.460762172378306 0.645285182196913 HGF other 1 1 1 -0.204213813562021 -0.460762172378306 1.18171471111408e-09 140.855419939643 34.3639478959402 4.09893008702541 5.27063935879623e-05 -207.868408788495 69.6079544689058 -2.98627377250901 0.00304265589844977 ZRANB1 other 1.42372988395024e-05 1 0.561164972531035 4.09893008702541 -2.98627377250901 0.00105287642576938 137.838882824074 37.1139922420816 3.71393306128316 0.000240940569426363 20.5537018133183 88.5894822455527 0.232010632552829 0.816678988185783 NCDN other 1 1 1 3.71393306128316 0.232010632552829 0.114120630854907 80.5619286478947 41.607270896038 1.93624640388433 0.0538023724230189 33.7259671103514 95.5827454867273 0.352845766656019 0.724458637022681 ADGRA2 other 1 1 1 1.93624640388433 0.352845766656019 0.000183688427374836 94.995804842237 22.6372955278602 4.19642906217855 3.51667513327135e-05 78.3802879531753 104.352091928374 0.751113719952775 0.453136220489593 ZFP64 other 1 1 0.379941581398637 4.19642906217855 0.751113719952775 1.93741324934401e-17 118.794831957844 13.2468883766438 8.9677536777087 2.62409346086522e-17 -17.7888401594372 43.7138227302686 -0.406938561955593 0.684326018309811 MNAT1 essential 2.74608953962021e-13 1 3.83878632389973e-13 8.9677536777087 -0.406938561955593 0.00071055642402613 102.414030578622 26.595867030291 3.85074983500174 0.000142473104448275 75.817483853961 79.7300134968741 0.950927768962858 0.342365490395009 SAMD4A other 1 1 1 3.85074983500174 0.950927768962858 0.298534482668257 -138.569719199086 90.3136471708813 -1.53431650187817 0.125942974628912 -118.768933699936 175.949896075961 -0.67501565132304 0.500154771753488 RUNX3 other 1 1 1 -1.53431650187817 -0.67501565132304 4.32705296217616e-13 85.9921551895825 18.9179969025787 4.54552115810216 7.83085923290853e-06 -113.055150616802 44.6357691203388 -2.53283751674589 0.0118010063494508 MRE11 other 5.74373010199264e-09 1 0.0885748487834284 4.54552115810216 -2.53283751674589 0.0205407558863849 29.0300302870893 12.371056854382 2.34660875208947 0.0195703929330447 -16.6792229945309 43.6043372161785 -0.382512934707385 0.702341376298278 PLEKHB1 other 1 1 1 2.34660875208947 -0.382512934707385 0.0015917979375974 371.034190853366 527.442017695765 0.703459675955099 0.4822840522006 -3472.26885290222 1170.16031175444 -2.96734457494649 0.0032316814781778 SERPINB1 other 1 1 1 0.703459675955099 -2.96734457494649 0.00329195329391707 140.959168256997 43.9921317923581 3.20419044301653 0.00149132968368642 -102.239104505476 153.0207083529 -0.668139009458053 0.504527989626366 SPAST other 1 1 1 3.20419044301653 -0.668139009458053 0.021924918108526 -0.925103353456256 9.17184078696257 -0.100863433518303 0.919722433345366 74.5450705598122 27.705658107857 2.69060818803189 0.00750905889771068 NRXN3 other 1 1 1 -0.100863433518303 2.69060818803189 5.04475126994391e-06 44.3692435215397 27.2090530665469 1.6306794438242 0.103941780165944 -167.700898811747 53.5106882077418 -3.13397013622195 0.00188427388321348 OSBPL5 other 0.0494335176941804 1 1 1.6306794438242 -3.13397013622195 7.221113614084e-08 190.920414963675 50.5536686896592 3.776588720706 0.000189726625000879 -286.519562524236 105.617642872357 -2.71280019826334 0.00703499574488271 AQR essential 0.000802121300252451 1 1 3.776588720706 -2.71280019826334 0.415338336848893 21.1797009775733 17.3452660423289 1.22106521317615 0.222968728400012 2.24450833812536 32.3481893711006 0.0693859032533848 0.944726197626017 CPS1 other 1 1 1 1.22106521317615 0.0693859032533848 2.06536887090872e-24 357.103633078048 34.995627376345 10.2042357817374 2.41397491107187e-21 -445.215069615352 166.405788841321 -2.67547825538626 0.00784734095114719 RTFDC1 essential 3.07017082660582e-20 1 3.6038231447392e-17 10.2042357817374 -2.67547825538626 0.017976609964137 234.787395280626 83.3012997885885 2.81853219429344 0.00512472299606948 66.418078135916 218.326619572379 0.304214292631859 0.761162365688094 NLRP2 other 1 1 1 2.81853219429344 0.304214292631859 0.532005382245617 31.6782625185052 28.9835809257194 1.09297269373622 0.275227906365477 54.420894574615 148.418225197293 0.366672586889332 0.71410558772304 SLC45A4 other 1 1 1 1.09297269373622 0.366672586889332 1.75161005343774e-09 511.97715030231 80.4357548906627 6.36504438850915 6.78692389879066e-10 -147.82215624755 220.476837879821 -0.670465694578429 0.503046064448562 RNF10 other 2.09720271698101e-05 1 9.07208117551347e-06 6.36504438850915 -0.670465694578429 0.00107962263209716 18.8695389221558 7.38336865712308 2.55568153216236 0.0110643139096571 -39.6424071856286 21.8442777086132 -1.81477308219706 0.0705038158334557 ZNF839 other 1 1 1 2.55568153216236 -1.81477308219706 2.30632144102905e-05 27.1492750299781 28.2489256048605 0.961072835467656 0.337241175244685 -200.064365914426 53.3100958977736 -3.75284198134 0.000207573148028825 ZDHHC6 other 0.212942658650213 1 1 0.961072835467656 -3.75284198134 0.914883631512249 10.6706390776649 27.6962687452644 0.385273524596679 0.700290740273156 19.1051914301761 50.658522195623 0.37713676992786 0.706321947855725 GRAMD1B other 1 1 1 0.385273524596679 0.37713676992786 7.82400469425922e-18 933.602722119025 195.48873618781 4.77573665022875 2.73029704098256e-06 -1389.56084795909 367.880389743258 -3.77720826306849 0.000189072532667416 RNH1 other 1.11382530827474e-13 1 0.031775196962955 4.77573665022875 -3.77720826306849 1.16763625655687e-07 372.017554700761 98.7377705249707 3.76773298326275 0.000196601170274036 -477.193654983227 186.129957832882 -2.56376598662144 0.0108180769977347 NDUFS1 other 0.00128346577320731 1 1 3.76773298326275 -2.56376598662144 4.9264991524827e-07 277.138054439845 50.793740019633 5.45614586231935 1.01716576194418e-07 -18.790233000914 241.137279349908 -0.0779233847689224 0.937940771412993 RB1CC1 other 0.0052112508034962 1 0.00126606622389192 5.45614586231935 -0.0779233847689224 3.25165474371222e-13 415.156369124687 54.2948789650485 7.64632644990218 2.45549548785813e-13 -118.830992459854 103.992883775199 -1.14268388514671 0.254026751540424 ERP44 other 4.32567630556036e-09 1 3.47305281802655e-09 7.64632644990218 -1.14268388514671 4.36412884179282e-09 135.003098203668 64.0370714864338 2.1082022501961 0.035793106058643 -362.636320961382 90.7747513983104 -3.99490293694301 8.0411987283751e-05 ALAS1 other 5.15098127196806e-05 1 1 2.1082022501961 -3.99490293694301 2.7685723263154e-06 249.492499287658 48.3134568749337 5.16403742198587 4.31518399017677e-07 719.880363628376 624.392649774147 1.15292895246087 0.249822074939991 BIRC3 og 0.027685723263154 1 0.00523216058808933 5.16403742198587 1.15292895246087 2.53955908248713e-08 179.031836822792 41.6037595847149 4.30326101799145 2.24126275688748e-05 -163.19267327423 77.4160821570773 -2.10799447255819 0.0358112125798189 AKAP11 other 0.000289204988313635 1 0.245507922389454 4.30326101799145 -2.10799447255819 2.74618469528486e-06 30.6290761851722 5.94637970285121 5.15087796537547 4.57991390756273e-07 8.1195093865908 20.2896691336047 0.400179487064324 0.689295568626151 GLRX2 other 0.0274645931375438 1 0.00554490176788619 5.15087796537547 0.400179487064324 6.38643758647817e-06 130.576658681971 27.5717033047099 4.73589379803262 3.29876162123797e-06 -41.6815137285914 91.350834728135 -0.45627950584839 0.648502433342104 SNAPC1 essential 0.0620059225271165 1 0.0381996595739357 4.73589379803262 -0.45627950584839 4.70312588736549e-19 299.578268998243 33.754323001974 8.87525633326206 5.30373111437821e-17 -305.173026227402 129.803180349983 -2.35104429186231 0.0193348622726785 DERA other 6.77014971486262e-15 1 7.74662966566081e-13 8.87525633326206 -2.35104429186231 1.544805987108e-21 721.235229103276 73.7437213540926 9.78029337087758 6.37559170845131e-20 -539.050065278068 281.410173639038 -1.91553154709148 0.056321377753939 STRAP essential 2.26530349949517e-17 1 9.46265321368343e-16 9.78029337087758 -1.91553154709148 0.893884822057157 -8.89172962857127 21.6362575901684 -0.410964308014695 0.681373773504772 -15.7642012782894 39.5714130944992 -0.398373473311236 0.690620574910481 ABCC2 other 1 1 1 -0.410964308014695 -0.398373473311236 0.00043252334117269 128.526827808437 34.4719252265886 3.72844936752481 0.000227795525153652 0.893657871764617 79.7658403745493 0.0112035160360418 0.991068055909839 DEF6 other 1 1 1 3.72844936752481 0.0112035160360418 6.72324382416301e-11 347.451976713539 48.8892106414597 7.10692547813173 7.9730457114373e-12 -28.6876525826511 202.449897110586 -0.141702480426458 0.88740559833251 PLEKHO1 other 8.46254700147398e-07 1 1.10482494423387e-07 7.10692547813173 -0.141702480426458 0.598820376305439 -65.6445786989785 214.631323122824 -0.305848082860735 0.759919812973867 375.022033981295 456.865160514605 0.820859339676672 0.412339386573767 GCLM other 1 1 1 -0.305848082860735 0.820859339676672 9.80721795717109e-24 314.919680295977 29.4508506737946 10.6930588791512 5.19402173929434e-23 -56.0020647694628 102.345092970073 -0.547188567075109 0.584631782424737 UBR2 other 1.45411620650976e-19 1 7.79155201111544e-19 10.6930588791512 -0.547188567075109 0.000253415497546111 1142.76978468966 306.339954199545 3.73039745231952 0.000226114591274589 -586.19909291756 697.546496707621 -0.840372786164629 0.401326862685553 EHD2 other 1 1 1 3.73039745231952 -0.840372786164629 0.0238226201533568 23.4186376079116 28.3247596826347 0.82679033715753 0.408971975146586 -143.600761080206 62.8102717531589 -2.28626237511835 0.0228920094729777 DEPDC1 other 1 1 1 0.82679033715753 -2.28626237511835 0.185094532507773 -6.05194949843231 16.9352314672477 -0.35735853449282 0.721060460440748 -71.9835402730647 39.093822139614 -1.84130218877021 0.0665085589359226 CCDC28A other 1 1 1 -0.35735853449282 -1.84130218877021 0.120327401004226 20.9536435904056 40.4333272800487 0.518227041897312 0.604657990623008 -172.85993337858 96.7263009507218 -1.78710373165872 0.0748671042288529 RRAGD other 1 1 1 0.518227041897312 -1.78710373165872 0.00237214343272757 17.1368837350485 12.2150466079019 1.40293232479053 0.161612603565953 -79.4365929516926 28.3712401966504 -2.79989850288854 0.00542440579805152 HSF2 other 1 1 1 1.40293232479053 -2.79989850288854 4.29411072918377e-13 159.016974556695 21.0411263062492 7.55743643387887 4.54362175142562e-13 -94.6138429040256 115.071134051952 -0.822220478519917 0.411575340371977 PHF20 other 5.70129081513729e-09 1 6.40150868558356e-09 7.55743643387887 -0.822220478519917 0.128185478405385 9.33543835654676 4.75311178584067 1.964068756884 0.0503874285164297 -1.4551362566407 13.430420780973 -0.108346289395653 0.913788908522175 HSD17B6 other 1 1 1 1.964068756884 -0.108346289395653 0.12746956877639 2.92178546855722 23.0468643227174 0.126775834996226 0.899197944059827 108.873201737675 58.4410406284371 1.86295795842994 0.0633900064350957 NR1H3 other 1 1 1 0.126775834996226 1.86295795842994 0.0118362101844249 25.1435264807415 709.583897371573 0.0354341841378837 0.97175575869553 -5867.13574937008 2025.03331491565 -2.89730332145892 0.0040250157849755 TYMP other 1 1 1 0.0354341841378837 -2.89730332145892 0.0029269157362616 214.819167321287 64.1327328939084 3.34960257621723 0.000906307725517659 12.3162492491104 182.081195394772 0.067641522357141 0.946113377050302 NCAPH2 essential 1 1 1 3.34960257621723 0.067641522357141 1.5955848350546e-11 189.380259621911 28.0543724326632 6.75047214392217 6.96664721420997e-11 -135.677567160431 125.366746826028 -1.08224525717902 0.279960963321383 TOMM34 other 2.04139123796886e-07 1 9.49136016463966e-07 6.75047214392217 -1.08224525717902 5.50773487744023e-10 235.523822709701 56.7231601093489 4.15216328313984 4.23169945823164e-05 -526.152954418771 129.198639211484 -4.07243418065353 5.87423433119652e-05 SEC63 essential 6.72990124674421e-06 0.845184835572555 0.454399887824914 4.15216328313984 -4.07243418065353 1.10495623510953e-07 350.130465723096 76.7802070919685 4.56016568571773 7.30385238676586e-06 -411.404814080293 166.846213780192 -2.46577255041754 0.0141993061981544 KPNA6 other 0.00121616038873044 1 0.0827672552468308 4.56016568571773 -2.46577255041754 0.56766964529732 440.557166136877 1436.81349893192 0.306620982099884 0.759331295828035 2951.78604584797 2855.64876120286 1.033665654527 0.30207303857471 VIM other 1 1 1 0.306620982099884 1.033665654527 0.0103344426301378 -80.4208358362657 44.8109462778344 -1.79466943941877 0.07365900191605 -270.634836522784 90.6152975830951 -2.98663519009701 0.00304056636329888 FAS ts 1 1 1 -1.79466943941877 -2.98663519009701 0.0999481965635973 118.63720490038 55.615646873054 2.13316236654005 0.0336743052519418 27.5993940533111 128.509478325979 0.21476543530355 0.830087431290382 RNASET2 other 1 1 1 2.13316236654005 0.21476543530355 3.3650684631587e-14 7515.73917861147 1047.80237715958 7.17285944605834 5.24676779514777e-12 -2647.91878111181 2751.18127966552 -0.96246612343689 0.336551421615079 CD44 other 4.55966776758005e-10 1 7.28723579068074e-08 7.17285944605834 -0.96246612343689 0.051239975367169 33.509594688429 14.1639905974746 2.3658300574136 0.0185853670075839 -3.29844943942953 65.3877567922287 -0.0504444501729954 0.959799687313241 KCNG1 other 1 1 1 2.3658300574136 -0.0504444501729954 0.00767163692676162 57.2459686271588 31.9894698158754 1.78952539559594 0.0744757672875477 -147.775596922088 70.2851198685216 -2.10251611149733 0.0362890032639138 AGPAT4 other 1 1 1 1.78952539559594 -2.10251611149733 0.000376187039241811 -168.916925958746 42.0619179592133 -4.01591116511953 7.38392878579262e-05 44.6979760839278 147.231885927409 0.303588966495788 0.761638350045792 SLAMF7 other 1 1 0.776198593962521 -4.01591116511953 0.303588966495788 0.538295914198613 50.712782235444 48.1540433886893 1.05313653157017 0.29307297598241 7.08906271746953 105.18230212504 0.0673978661262055 0.946307058724122 BTN3A1 other 1 1 1 1.05313653157017 0.0673978661262055 5.1494665615872e-11 52.6914070858678 17.4712832648134 3.01588648568172 0.00276751319084277 -124.152208923863 28.3371912562433 -4.38124610873385 1.60152643348082e-05 MIPEP essential 6.50274637397231e-07 0.234479485125927 1 3.01588648568172 -4.38124610873385 0.0038213120739188 98.7354481034617 32.1429743223318 3.07175829820029 0.00231242708235125 -66.2572929457514 105.962911976795 -0.62528758137811 0.532232193117351 PRKCH other 1 1 1 3.07175829820029 -0.62528758137811 0.330773874211179 59.6068639754584 167.881346749149 0.355053525181234 0.722785602025166 -518.185379129693 388.84692265902 -1.33262049648285 0.183613453952559 IFNGR1 other 1 1 1 0.355053525181234 -1.33262049648285 0.000123552673439055 122.016500744651 30.9156840206697 3.94675080334863 9.74262034423026e-05 -12.5150297021302 46.9777069122003 -0.266403588525944 0.790099978032367 B4GALT7 other 1 1 1 3.94675080334863 -0.266403588525944 0.947319944129118 6.68504089336791 38.6072543004827 0.173155045974982 0.862639031814453 -38.8136439252144 135.525675939082 -0.286393287886355 0.774762241169308 SH2D2A other 1 1 1 0.173155045974982 -0.286393287886355 0.271390116298619 -15.3941104030416 44.2220841421928 -0.3481091111297 0.727987128213501 -282.500092817441 175.110828576856 -1.61326455430169 0.107672722139864 VRK2 other 1 1 1 -0.3481091111297 -1.61326455430169 1.32445529926871e-05 152.942268713975 51.5808754109218 2.96509641404013 0.00325328581829972 -407.492729718618 125.534131119773 -3.24607121651902 0.00129399552840931 VEZT essential 0.12509480301593 1 1 2.96509641404013 -3.24607121651902 0.389763245541298 4.18624263946443 19.2117366945291 0.217900271382365 0.827647011918043 -59.2664297853253 47.60001634883 -1.2450926350739 0.214017314111416 POU2F2 other 1 1 1 0.217900271382365 -1.2450926350739 5.69728834731107e-26 217.401698028004 18.7432247637661 11.5989484610076 3.43192563650864e-26 -135.912641668188 114.134599741403 -1.19081016603315 0.234613448403975 BRD9 other 8.52200390990789e-22 1 5.18220771112805e-22 11.5989484610076 -1.19081016603315 1.30496403078534e-05 96.1235495798524 71.0338779747228 1.35320712201659 0.176944645162313 -535.513614570159 139.001208586466 -3.85258243446883 0.000141212699770962 SNX1 other 0.123332150549523 1 1 1.35320712201659 -3.85258243446883 0.00113460801863424 31.2736145840027 22.6546311042382 1.38045128345312 0.16841426071185 -164.150158142596 53.2428101631787 -3.08304835224716 0.0022277954648585 TBPL1 other 1 1 1 1.38045128345312 -3.08304835224716 1.33940681001108e-09 577.679816820925 94.329187468593 6.12408346052237 2.67156417504336e-09 -664.135062223001 484.938208660193 -1.36952512786712 0.171795488956447 ARNTL2 other 1.61063668903832e-05 1 3.51577845435707e-05 6.12408346052237 -1.36952512786712 0.0166445176562269 -1.8475671587897 65.4442016247168 -0.0282311818758885 0.977495476157029 -428.830270220593 152.368637950183 -2.81442609181031 0.00519094999068282 BCLAF1 essential 1 1 1 -0.0282311818758885 -2.81442609181031 4.44530011642711e-24 576.137667923318 54.8477602171867 10.5043062039712 2.4069876138975e-22 -289.027285057375 175.399902174332 -1.64781896383333 0.10038060549556 SLC39A9 other 6.59815896281277e-20 1 3.60398255428873e-18 10.5043062039712 -1.64781896383333 0.00542680783500991 154.219222187406 50.7287078163566 3.04007787357202 0.00259397269537778 71.9194856471995 122.261254307179 0.58824429746568 0.556852873843634 ANK1 other 1 1 1 3.04007787357202 0.58824429746568 0.760930779156945 6.76416222470742 9.62330263661822 0.702894056243092 0.482634405776975 1.34874735540031 17.7505576941342 0.0759833791501668 0.939479951741374 IBSP other 1 1 1 0.702894056243092 0.0759833791501668 0.0198644195521673 10.3122322528453 12.5760497094033 0.819989781460124 0.412834191036486 -67.8418143798874 27.7111247233415 -2.4481797493677 0.0148963249343946 TFB1M other 1 1 1 0.819989781460124 -2.4481797493677 9.5437105603008e-19 337.817503475921 34.7293221429599 9.72715511363359 9.24237623362991e-20 2.75997638803116 65.0574899005692 0.04242365317582 0.966187430856126 RABEP1 other 1.36980877671997e-14 1 1.37045954792264e-15 9.72715511363359 0.04242365317582 5.55462105473245e-12 275.912506948481 58.0876004606933 4.74993810658758 3.08038011841054e-06 -471.240433585356 153.315618956503 -3.0736622712853 0.00229697311298209 NUP160 essential 7.1915678795621e-08 1 0.0357267611861774 4.74993810658758 -3.0736622712853 0.00460584722053002 121.532547725723 74.510410781203 1.63108143481585 0.103859975276873 -354.955279659422 172.510153016832 -2.05759066032936 0.0404418249974421 BAK1 other 1 1 1 1.63108143481585 -2.05759066032936 0.0297223375487785 -88.0539835140695 47.1442411149082 -1.86775693980202 0.062718516508481 -212.870400786481 83.8890858089505 -2.53752199983766 0.0116428210508325 IKZF2 other 1 1 1 -1.86775693980202 -2.53752199983766 0.434282379551385 389.21313087547 677.542721954895 0.574448102331443 0.566068206047965 -1814.3083791462 1633.43901046102 -1.11072918396514 0.267518826124632 GRN other 1 1 1 0.574448102331443 -1.11072918396514 2.05956445255788e-05 -2.77523198069145 29.1166917773622 -0.0953141243487406 0.92412498242481 -193.928889967651 43.3564456292236 -4.47289640913129 1.07340055251395e-05 FAM13B other 0.190983411685692 0.157897221274803 1 -0.0953141243487406 -4.47289640913129 0.152973462157995 54.722488079092 28.2653611187795 1.93602649720737 0.0537504482973178 19.17495230215 111.194688011069 0.172444859058746 0.863197505564474 ARHGAP31 other 1 1 1 1.93602649720737 0.172444859058746 0.677896735361692 8.66689584049503 10.8467490669709 0.799031653353749 0.424872212932024 -2.51568256728614 24.9005500291153 -0.101029196718331 0.919591353913041 CENPQ other 1 1 1 0.799031653353749 -0.101029196718331 2.93126078065594e-19 219.655757063224 111.294684465622 1.97364104240821 0.0492852437215658 -1633.39148862348 206.515094587937 -7.90930799456871 4.28111973613927e-14 SARS essential 4.22775742394006e-15 6.5689501231321e-10 1 1.97364104240821 -7.90930799456871 1.09524040361534e-18 230.221746874756 49.4723778237567 4.65354116785959 4.79012294965196e-06 -509.007549970908 89.7484703519953 -5.67148997609174 3.17440505654843e-08 RANBP3 other 1.57123188302656e-14 0.000481271550623308 0.0548900188800618 4.65354116785959 -5.67148997609174 6.61866612417976e-05 47.7076477771458 10.9096763962617 4.37296635063285 1.66298355004054e-05 4.41784769897102 33.8156305591606 0.130645137349782 0.896138641206599 ARID4A other 0.581846938976643 1 0.183809571785981 4.37296635063285 0.130645137349782 1.02272252000959e-11 171.385892122665 61.5234130437356 2.78570195708796 0.0056596712458033 -548.123569677874 111.409444733019 -4.91990217697786 1.38783849949575e-06 PNPLA6 other 1.31470979947232e-07 0.0207565125984584 1 2.78570195708796 -4.91990217697786 1.19270417843959e-10 14.3186592228147 6.72590557490163 2.12888198672401 0.0340572316646019 -53.1169523697292 10.9055178260521 -4.87064926370014 1.78171358270402e-06 IFT88 other 1.48694429926064e-06 0.0266116740712673 1 2.12888198672401 -4.87064926370014 5.40721992394212e-06 87.9379655891668 22.6775890190603 3.87774756457822 0.000128044240388981 -136.111129679934 66.9781961822809 -2.03217072776204 0.042964569715243 ALG1 essential 0.0528447603166863 1 1 3.87774756457822 -2.03217072776204 0.00991303648900787 36.118901885576 20.0330873429519 1.80296233262735 0.0723347779749138 -112.275687722513 52.3038807821737 -2.14660338857264 0.0325762752535355 ZCCHC8 other 1 1 1 1.80296233262735 -2.14660338857264 5.69268777470345e-31 434.077955981484 48.2410703508665 8.99809960318775 2.10550692714335e-17 -399.055815056921 107.216512960411 -3.72196226158064 0.00023359690830486 ABCF2 other 8.61474440945874e-27 1 3.08140938787429e-13 8.99809960318775 -3.72196226158064 0.00244511649154687 75.4078308088023 22.0975352799121 3.41249962285849 0.000727482467545134 116.044107840335 73.6722986376346 1.57513895977525 0.11622496710503 FUT8 other 1 1 1 3.41249962285849 1.57513895977525 1.30285570344607e-05 348.47853900446 122.346070422461 2.84830185228804 0.00468251936852704 -666.437266591618 261.988642335313 -2.54376396110584 0.0114409991252847 UBA6 other 0.123158949646757 1 1 2.84830185228804 -2.54376396110584 0.000307026434248445 30.4276512496283 14.495038145587 2.09917703865387 0.036594338538669 -97.0563785158584 46.8500911296492 -2.07163692056163 0.0391104057491393 GAB2 other 1 1 1 2.09917703865387 -2.07163692056163 0.0137924412109316 55.3621633389783 35.8759490725501 1.54315536648305 0.123781389958738 -123.324034538452 69.8226427215724 -1.76624701861006 0.0783078213691022 PIAS1 other 1 1 1 1.54315536648305 -1.76624701861006 2.25588512946048e-07 165.318628319368 49.5058906020542 3.33937287682101 0.000938847988123626 -168.652725469008 73.6753946307232 -2.28913229870476 0.0227226968706612 SLC4A7 other 0.00244086771007624 1 1 3.33937287682101 -2.28913229870476 0.615314186732574 25.7719165659009 26.2067718420952 0.983406759183678 0.326159616828891 17.8670143087465 56.6874078450191 0.315184888284082 0.752829312044722 APBA2 other 1 1 1 0.983406759183678 0.315184888284082 0.000177843972106778 246.490030080976 58.5164020482834 4.21232374946072 3.29018412819718e-05 35.6336689666935 108.182279010015 0.329385452892841 0.742079849980382 MAP2K3 other 1 1 0.356359842925037 4.21232374946072 0.329385452892841 0.828261446553781 -4.56686344435466 8.99692079029398 -0.507602940028266 0.612121679738122 10.9349768441502 45.3627044512805 0.241056545821566 0.809683410981268 EFCAB1 other 1 1 1 -0.507602940028266 0.241056545821566 0.16020201788255 3108.80215118849 2786.73412489514 1.11557185287831 0.265450403237062 -16857.932172059 11501.8855730436 -1.46566683045153 0.143730244379699 TMSB10 other 1 1 1 1.11557185287831 -1.46566683045153 9.01163100580965e-19 81.0443825387991 8.31982256327867 9.74111910709562 8.31322012975288e-20 51.7897224860335 33.7455331090476 1.53471341877091 0.125842322533538 ASTE1 other 1.29416032874432e-14 1 1.23301680964495e-15 9.74111910709562 1.53471341877091 0.055176210843036 128.101350672361 69.3609884004379 1.8468789679409 0.0656877685050547 -629.912174541503 420.130779090568 -1.49932403406634 0.134775473822174 RNF19A other 1 1 1 1.8468789679409 -1.49932403406634 0.000191233712068748 30.110843373494 13.4119999212469 2.24506736879659 0.0254485728384641 -88.6012734699482 30.0168322891072 -2.95171964238547 0.00339435508733502 PEX3 other 1 1 1 2.24506736879659 -2.95171964238547 3.11686371287275e-09 129.779266652087 35.900648766487 3.61495602757005 0.000348972336576479 -305.376230143741 94.0570501191086 -3.24671281692366 0.00129157529106731 GABARAPL2 other 3.69909385443738e-05 1 1 3.61495602757005 -3.24671281692366 0.684734731391905 11.0916939657608 14.527403985211 0.763501447130693 0.445726928451628 -20.6546413929011 46.8418343337861 -0.440944332916597 0.659551049759661 MYOC other 1 1 1 0.763501447130693 -0.440944332916597 0.0427843932992865 115.107999593415 45.948293519905 2.5051637563765 0.0127472384200733 42.1002405638013 142.455353130957 0.295532878466837 0.767782794359421 SH3YL1 other 1 1 1 2.5051637563765 0.295532878466837 0.000492623753266565 120.142826731081 30.475557567862 3.94226837240142 9.91790798405984e-05 32.4901987192298 131.038491077183 0.247943931986311 0.804336813425038 FAM136A other 1 1 1 3.94226837240142 0.247943931986311 1.35553245213625e-09 832.580727106612 213.124311242345 3.90654976081015 0.000114255441167308 -1701.48197646132 498.70732116451 -3.41178463650437 0.000728236147454859 VCL other 1.62948556071299e-05 1 1 3.90654976081015 -3.41178463650437 7.42717287741034e-06 75.1306251710287 24.6147040192327 3.05226604034424 0.00246212004465604 -80.2842443641723 35.5320045993719 -2.25949099324364 0.0245272886046851 DEPDC1B other 0.0717316356500291 1 1 3.05226604034424 -2.25949099324364 0.211435304637662 -4.29787954203067 19.8393788889693 -0.216633774982759 0.828631802749462 -66.6438543286325 38.8222876435505 -1.7166390332411 0.087012826121146 DAPK2 other 1 1 1 -0.216633774982759 -1.7166390332411 2.70031607949402e-15 177.701924116917 20.5784474386642 8.63534164307453 3.10253039087169e-16 69.7936301622756 95.3695530046473 0.731822976656655 0.464827713908151 NSMAF other 3.72859644256535e-11 1 4.50921767009292e-12 8.63534164307453 0.731822976656655 9.96961278577867e-08 321.219874946559 55.1866878403761 5.8206043434907 1.43588748116851e-08 -75.904801731508 181.015753807784 -0.41932704825299 0.675261145180252 ADSS other 0.00110044585929425 1 0.000184626412328647 5.8206043434907 -0.41932704825299 0.0954462974826183 -3.04768498275275 3.88194889129567 -0.78509147546647 0.432986283962675 13.1665452072099 8.31729738929486 1.58303167374494 0.114411373805318 STAP1 other 1 1 1 -0.78509147546647 1.58303167374494 0.0155694809971179 1143.72931356484 396.096942274868 2.887498466906 0.00414840421488987 813.197931328967 931.228858176017 0.873252503065428 0.383182330596217 TIMP2 other 1 1 1 2.887498466906 0.873252503065428 4.52155425830784e-10 164.556608830835 54.6355760848873 3.01189482426548 0.00280313287991382 -397.420054321606 109.414835535155 -3.63223188498889 0.000327132246705624 RFC1 other 5.54161689898209e-06 1 1 3.01189482426548 -3.63223188498889 5.23684262685257e-20 272.942162162162 28.7417809788282 9.49635523154314 5.58208032936904e-19 -102.549581346052 119.369118289076 -0.859096413007822 0.390938541754722 TBC1D23 other 7.59761128303771e-16 1 8.24696547860983e-15 9.49635523154314 -0.859096413007822 2.94415339745269e-09 176.783410105591 58.904494741746 3.00118710602069 0.00290144742369493 -380.43990078662 102.309560741302 -3.7185175855519 0.000236669742735038 CUL3 essential 3.4976542361738e-05 1 1 3.00118710602069 -3.7185175855519 0.251342087145228 10.5842952395073 65.2983533175979 0.162091304018455 0.871342708400105 -147.40633986571 124.899678718332 -1.18019791066183 0.238853350345512 MYOM2 other 1 1 1 0.162091304018455 -1.18019791066183 0.000181831972841784 106.700321771184 31.3566332976619 3.40279904281498 0.000751736642799544 -85.422867680268 66.7455243756792 -1.27982914928442 0.201532297608322 ZZZ3 other 1 1 1 3.40279904281498 -1.27982914928442 5.89032916610039e-05 53.5516797290979 29.7162572103892 1.80210042435544 0.0724735250628291 -114.307240936655 56.0594017479642 -2.03903783080963 0.0422702211535815 USP2 other 0.52105851803324 1 1 1.80210042435544 -2.03903783080963 1.57611500067289e-07 70.6176359956294 12.7838973256493 5.5239520622513 6.87237657613344e-08 -35.5949416969675 32.3754287970308 -1.09944309680408 0.272401286747145 TUBG2 other 0.00172032952323446 1 0.000861246232521042 5.5239520622513 -1.09944309680408 1.18439957241732e-09 72.6057433338969 14.323473067649 5.06900407401079 6.77896867617847e-07 -48.5768472784013 21.6965578153184 -2.23891954161064 0.0258481476486746 RPL26L1 other 1.42684616489114e-05 1 0.00814018558635511 5.06900407401079 -2.23891954161064 0.940222252279781 -4.60986693756303 16.466926595856 -0.279947014443067 0.779700741023511 -7.71575848033672 26.3748427497224 -0.29254235005507 0.770063368182185 FLT4 other 1 1 1 -0.279947014443067 -0.29254235005507 1.09868821244816e-27 601.70857039066 49.1120621651174 12.2517472055578 1.5181175663302e-28 15.3050968057257 279.193785991524 0.0548189020445834 0.956317057583271 NSUN2 other 1.6518777274158e-23 1 2.30116260704331e-24 12.2517472055578 0.0548189020445834 2.68424359131318e-14 124.213336048037 23.150626088263 5.36544176276127 1.55229943447795e-07 -200.550430452411 46.3584424801644 -4.32608214864469 2.03110640111383e-05 FBXO42 other 3.64547122136243e-10 0.296541534562619 0.00191864210101475 5.36544176276127 -4.32608214864469 0.0214632186543713 32.8708743779835 23.4911165560512 1.39928956972103 0.162694741069459 -61.8864147776771 34.2965424441369 -1.80445054712087 0.0721007976145933 MFAP3 other 1 1 1 1.39928956972103 -1.80445054712087 0.000463089631653635 65.9802526383116 27.646628762316 2.3865569001399 0.0175969722546032 -156.697763892647 65.0863457962213 -2.40753666495967 0.0166352300552058 MRI1 other 1 1 1 2.3865569001399 -2.40753666495967 5.59108657884019e-09 112.58124051185 17.8437052219245 6.30929726262916 9.3251064397536e-10 111.701506721759 58.4639653762883 1.91060435266102 0.0569489394122665 METTL1 essential 6.56952673013722e-05 1 1.24210417777518e-05 6.30929726262916 1.91060435266102 0.0348682825187943 14.5583985083131 5.76013472649738 2.52744062414765 0.0119709002220277 -2.02043449192684 16.0417842561158 -0.125948239900843 0.899851990213448 HOXC8 other 1 1 1 2.52744062414765 -0.125948239900843 5.28198679852911e-07 94.6107615096638 23.4216782081715 4.03945270995378 6.73168125319774e-05 -73.807488679871 42.608592043251 -1.73222078319206 0.0842100315349584 AGA other 0.00557513706584748 1 0.710057738587298 4.03945270995378 -1.73222078319206 1.3606500597917e-11 41.1579464124718 25.8657016163267 1.59121708828855 0.112563752916291 -246.57737406512 48.2870159244944 -5.10649435141508 5.6927714207186e-07 PI4K2B other 1.74367305162306e-07 0.0085550968910559 1 1.59121708828855 -5.10649435141508 7.15536519455002e-09 214.73902370081 57.1857958283634 3.75511122281701 0.000205888482517957 -224.268562493793 107.286788289673 -2.09036514252129 0.0373763502867692 BOD1L1 other 8.36032869331224e-05 1 1 3.75511122281701 -2.09036514252129 5.07221259444282e-09 170.536231503727 81.8570157700782 2.08334288636582 0.0380158853341995 -580.250757271624 117.497650252646 -4.93840307464837 1.27276073962752e-06 MAT2B other 5.9699942236592e-05 0.019043046186307 1 2.08334288636582 -4.93840307464837 1.50014250284013e-05 127.775208315005 27.9727018713927 4.56785364897764 7.05701509539855e-06 27.7680848634902 47.5582362084603 0.583875414171699 0.559718054514593 TLL1 other 0.141043398117029 1 0.0800830073025828 4.56785364897764 0.583875414171699 6.43989255103677e-10 181.971756252637 37.1632138313306 4.89655596199338 1.55238509954063e-06 -220.161489713109 99.4828289256857 -2.21306020436522 0.0276010292119813 EDC4 essential 7.84121317014237e-06 1 0.0183212489447785 4.89655596199338 -2.21306020436522 4.94173590895376e-17 555.91234576277 60.3517574843638 9.21120393066926 4.80463765688589e-18 386.71209464502 372.555445306377 1.03799877177208 0.30007182976756 TRIO other 6.96735345803391e-13 1 7.06185642809087e-14 9.21120393066926 1.03799877177208 0.669155978052917 377.053344203114 514.473748782352 0.732891318741759 0.464162908292182 548.570499938446 715.396172877801 0.766806590160707 0.4437636250748 VCAN other 1 1 1 0.732891318741759 0.766806590160707 3.4408240711901e-10 113.700981257114 26.5425483242617 4.28372512948137 2.43365160423707e-05 -354.110538355681 86.1233770815117 -4.11166573299294 4.99833071409828e-05 CLEC16A other 4.23393401959942e-06 0.7211591554301 0.2658764377629 4.28372512948137 -4.11166573299294 0.268268578839746 -5.82560938209532 41.2529774970685 -0.141216700843213 0.887788167923334 89.7149897807545 76.9490427937838 1.16590130979514 0.244528048768448 MSR1 other 1 1 1 -0.141216700843213 1.16590130979514 5.30454660296928e-06 1473.03635158751 454.216124109975 3.2430296358895 0.00130784245686611 -2733.69886033872 1223.6569807952 -2.2340401789415 0.0261730672498032 CDH1 ts 0.0518625521372306 1 1 3.2430296358895 -2.2340401789415 1.78693230656021e-24 445.408231321857 49.7654598512996 8.95014800732774 3.053710520094e-17 -265.314892667938 83.9727880186864 -3.15953416491183 0.00173259288386259 SKIV2L2 essential 2.65716833985504e-20 1 4.46605163563748e-13 8.95014800732774 -3.15953416491183 0.0201648197359912 38.3384747968541 13.8362447674131 2.770872837343 0.00592275673463342 -17.4407405674047 85.5609984930448 -0.203839843790772 0.838610280536637 DNAH5 other 1 1 1 2.770872837343 -0.203839843790772 1.88536451447597e-06 70.7439191525095 33.5070869069683 2.11131213372647 0.0355205995779403 -163.836113443303 46.1929731619724 -3.54677567232625 0.000448262807180177 ZFYVE16 other 0.0190836596155258 1 1 2.11131213372647 -3.54677567232625 0.000953638314155414 190.270333479402 52.1233131376438 3.65038832003923 0.00030586033408075 87.5560866268502 139.529769073433 0.627508288792269 0.530775009225599 RIPOR1 other 1 1 1 3.65038832003923 0.627508288792269 4.40146499640059e-05 337.253410744793 74.1935394616712 4.54558999599986 7.79479226901363e-06 328.058944504208 477.260025057572 0.687379892050742 0.492344375559915 RAI14 other 0.395251556676773 1 0.0881832939206712 4.54558999599986 0.687379892050742 0.000278711023884884 -2.11859980325427 8.66090312884471 -0.244616499196068 0.80691016503009 -48.9065510153849 12.4186294491394 -3.93816010177952 0.000100811874160355 SOX30 other 1 1 1 -0.244616499196068 -3.93816010177952 0.00096286090073353 158.52435546875 73.0246141306988 2.17083455155304 0.0306807858884665 -426.297995426831 168.986762787586 -2.52267093821237 0.0121327224262404 PNKP essential 1 1 1 2.17083455155304 -2.52267093821237 0.819856843569706 3.26762929966335 7.37705352840081 0.442945043991257 0.658109514650502 -8.54531446749957 24.3494940027713 -0.350944231799108 0.7258647800571 BEST2 other 1 1 1 0.442945043991257 -0.350944231799108 2.387715063398e-07 46.396161550539 8.93689105604924 5.19153263249575 3.71532155640203e-07 1.03666956469122 24.5683667967106 0.0421952982576775 0.966369326044515 PHLPP2 other 0.00258040366901422 1 0.00451708794827359 5.19153263249575 0.0421952982576775 1.12963191915147e-07 86.1753465717494 21.9982201469652 3.91737813314128 0.000109469598959784 -82.5562632696391 32.0145298626241 -2.57871234167399 0.010363336188563 SPDL1 essential 0.00124270807425853 1 1 3.91737813314128 -2.57871234167399 0.195923190938119 37.8221978384412 22.7408491345084 1.66318318259486 0.0972640696198615 -55.2796928912118 105.191536011019 -0.525514646781288 0.599592863339427 STAU2 other 1 1 1 1.66318318259486 -0.525514646781288 1.15813174024578e-06 43.0918956640258 17.1612110130594 2.511005524682 0.0125313029873789 -123.316536949131 33.2778416886043 -3.70566511203038 0.000248350361673454 PQLC2 other 0.0119391801101937 1 1 2.511005524682 -3.70566511203038 5.82931379347909e-13 95.7467035345655 12.5025986548624 7.65814421286956 2.25625684273703e-13 -32.5401352070449 23.6948054161801 -1.373302487001 0.170619760672716 CTNS other 7.71567973704892e-09 1 3.19282905815717e-09 7.65814421286956 -1.373302487001 2.5676471441322e-05 63.1974544861003 13.6045939346893 4.64530251983176 5.02563682560718e-06 20.7662969553893 55.188990859096 0.376276076661885 0.706969052464128 RTN4R other 0.236095154902956 1 0.057558618563679 4.64530251983176 0.376276076661885 1.08073008456539e-21 264.993008516535 25.0210914801295 10.59078532713 1.14356337833147e-22 -12.3593709475669 47.7602081336056 -0.258779670997088 0.795971619844938 PHF23 other 1.58607947210816e-17 1 1.71408714778104e-18 10.59078532713 -0.258779670997088 0.169419007060547 49.3878307201745 31.1198648524886 1.58701944736193 0.113514693489082 -73.4875106731639 98.9445154927101 -0.742714341540015 0.458209910159109 INPP4A other 1 1 1 1.58701944736193 -0.742714341540015 1.04135041894831e-08 114.817083720808 85.8702424023513 1.33709979742253 0.182142743277516 -523.979414726257 130.691077454116 -4.00929753532882 7.58860865314789e-05 RAB27B other 0.000120734167572867 1 1 1.33709979742253 -4.00929753532882 0.000572620633500943 155.634243670959 159.962880028322 0.972939744792059 0.331318115812576 -983.684484415372 311.298593783562 -3.15993873425365 0.00172879892416883 PSMA4 other 1 1 1 0.972939744792059 -3.15993873425365 0.0128063536622645 8.65903809478019 3.50882529990094 2.46778832078777 0.014124484537102 -8.48926448969718 8.39579715681558 -1.01113263352316 0.312726542513689 MYO16 other 1 1 1 2.46778832078777 -1.01113263352316 1.29148128705074e-22 453.975227442111 41.9911665671435 10.8112077981022 1.98341798338416e-23 325.980138970983 262.406167564429 1.24227315995134 0.215045414760176 LSG1 essential 1.90532234278596e-18 1 2.97750707665631e-19 10.8112077981022 1.24227315995134 2.99511723917875e-05 -12.5759216373532 40.3270219158627 -0.311848508515984 0.755359378008709 -233.623733670723 57.1649406207178 -4.08683593709626 5.53843832139703e-05 PARP3 other 0.273723764488546 0.7976458870476 1 -0.311848508515984 -4.08683593709626 0.00118785254258766 7676.99347256855 2463.92411319866 3.11575889510748 0.00200142847709988 11300.0245194813 4963.31542721081 2.27670892273544 0.0234656559188112 TNC other 1 1 1 3.11575889510748 2.27670892273544 4.86753452100698e-09 98.9886477089595 32.4631280194073 3.04926400344975 0.00248614530472489 -316.335521960815 71.6573077065917 -4.41456052543982 1.38712062964635e-05 THAP3 other 5.73444241919832e-05 0.203573823606899 1 3.04926400344975 -4.41456052543982 0.512770564166183 -9.55882783425534 21.8630633650044 -0.43721356310735 0.662251380457772 -115.523190687587 100.930360000301 -1.14458316295753 0.253237254851422 RIPOR3 other 1 1 1 -0.43721356310735 -1.14458316295753 1.74339091661807e-06 43.3641593443396 11.7090172699848 3.70348410498123 0.000250657595009424 -85.8716616745875 34.400458763017 -2.49623594458879 0.0130578861391307 TDP1 other 0.0177006479764233 1 1 3.70348410498123 -2.49623594458879 0.101240606083824 25.1556255812556 35.2099902821236 0.714445683730486 0.475472466396132 -115.999461958083 73.2590927082227 -1.58341384898236 0.114314935754257 AIFM2 other 1 1 1 0.714445683730486 -1.58341384898236 1.76365557628491e-06 19.4303555803038 4.48514876902502 4.33215408917809 1.98419448475682e-05 -20.8785517614788 13.0854766616366 -1.59555148821514 0.111585393444969 SPATA7 other 0.0178905221658341 1 0.218142341654164 4.33215408917809 -1.59555148821514 5.76735336881457e-28 110.501225365248 17.6377120997181 6.26505437556235 1.23105641457264e-09 -212.853473422442 41.8241061309118 -5.0892533783316 6.21268891125359e-07 MED17 essential 8.67640640804463e-24 0.00933083747581176 1.634719812911e-05 6.26505437556235 -5.0892533783316 0.721374381795058 44.1106170462668 56.6650494739292 0.778444869558642 0.436887452134446 -36.458214478112 236.569002544464 -0.154112390406091 0.877619185289425 RETSAT other 1 1 1 0.778444869558642 -0.154112390406091 0.00278605216929021 497.29951074333 238.96649029599 2.08104286976539 0.0382324179457076 -2580.56497664109 997.653134969615 -2.58663546095075 0.010137141962906 CAPG other 1 1 1 2.08104286976539 -2.58663546095075 0.0386079439558842 154.685023847701 188.939892438482 0.818699650197301 0.413567056340307 -923.559475669159 427.893741371642 -2.15838509978816 0.0316412632918324 AP2S1 essential 1 1 1 0.818699650197301 -2.15838509978816 0.525739960055221 -15.3879163830081 15.922720943914 -0.966412489247929 0.334569899191523 44.5796967511374 90.1631823800691 0.494433487975374 0.621340386486555 TG other 1 1 1 -0.966412489247929 0.494433487975374 8.07672548817572e-07 -82.9102827554461 31.8491803834467 -2.60321558536991 0.00966690499849772 -315.86527976471 59.2944682522039 -5.32706151307748 1.88919165231784e-07 ADAM28 other 0.00841419178716985 0.0028506012841824 1 -2.60321558536991 -5.32706151307748 2.19390170833196e-05 429.468456414343 105.018009531064 4.08947435141883 5.48685801042234e-05 150.664051950766 191.875557805456 0.785217531998138 0.432912492385272 BARX2 other 0.203001725071957 1 0.582923795027269 4.08947435141883 0.785217531998138 7.89211207008578e-31 324.241385392744 24.7634467384773 13.0935482777096 1.54664460281281e-31 143.357421528097 160.850104972441 0.89124854194319 0.373480439156961 DCUN1D1 other 1.19415547732468e-26 1 2.35275576979885e-27 13.0935482777096 0.89124854194319 4.99394197916157e-05 717.182573273297 239.745935038015 2.9914274590707 0.00299316073075217 -732.416370020376 358.003132091486 -2.04583788343285 0.0415920739537456 JADE2 other 0.445859139899545 1 1 2.9914274590707 -2.04583788343285 0.970459703703653 0.75793355928044 19.6608382455559 0.0385504193572093 0.96927333035159 -10.3227031169161 45.724844755709 -0.225756985552745 0.821537303917848 ZIC2 other 1 1 1 0.0385504193572093 -0.225756985552745 0.000303104350909122 -47.5178586840822 43.4884984234547 -1.09265346946204 0.275370453803749 -260.2491675484 64.1153651428378 -4.05907643150141 6.20293085499288e-05 LCP2 other 1 0.891733339713777 1 -1.09265346946204 -4.05907643150141 5.00575197575866e-07 136.704332666108 24.8557377106858 5.49991049379867 7.83550379239645e-08 36.5747449473753 63.4238917539394 0.576671407823277 0.564570703659968 TRIT1 other 0.0052910798383769 1 0.000979829749239177 5.49991049379867 0.576671407823277 0.976000735367127 -0.0307893263668637 3.44345591950388 -0.00894140279028161 0.992871459458626 -1.33965394920405 6.59656198479627 -0.20308365968389 0.83919871347236 ADRB1 other 1 1 1 -0.00894140279028161 -0.20308365968389 5.69747298435973e-16 209.591727712108 27.0854701633277 7.73816095671413 1.34986554483307e-13 -209.60778046421 94.0256731688361 -2.22926115176894 0.0264947715159391 CUL7 other 7.94227734019746e-12 1 1.91640411399951e-09 7.73816095671413 -2.22926115176894 2.28037000357564e-13 1186.45959566049 346.592447634812 3.4232124899346 0.000699338443761633 -2882.21555980294 508.91265200792 -5.66347790417693 3.30430108044132e-08 CTNNA1 ts 3.04543413977526e-09 0.000500766828740882 1 3.4232124899346 -5.66347790417693 8.69321724455466e-21 39.6361122627031 6.87190923057347 5.76784572275199 1.91272168633196e-08 -196.585443067346 25.6068725893241 -7.67705788286328 2.04930477508792e-13 CNTLN other 1.26877505684275e-16 3.14260887259732e-09 0.00024517266575403 5.76784572275199 -7.67705788286328 0.348855632480088 -10.3000706808926 27.9698117959967 -0.368256703191933 0.712947745436441 37.8801790582614 38.7671716342862 0.977120008021418 0.329315799458869 EPHA3 other 1 1 1 -0.368256703191933 0.977120008021418 0.00936079761860566 1788.11000509337 657.729980918915 2.7186080260401 0.0069154719219356 2277.02843485061 1291.63949984463 1.76289780168887 0.0788782098355103 HSPA5 essential 1 1 1 2.7186080260401 1.76289780168887 7.38555859780702e-14 2742.74579948171 387.698170971182 7.07443574626917 9.65805191447065e-12 466.400534693514 694.62868305598 0.671438634871239 0.502430123742194 DSG2 other 9.95204021054495e-10 1 1.33648122392445e-07 7.07443574626917 0.671438634871239 0.208148206793259 -6.40937327611111 4.8350787050089 -1.3255985408203 0.185927206459215 -30.6828312138967 22.5398570371152 -1.36127000110838 0.174395197170981 PREX2 other 1 1 1 -1.3255985408203 -1.36127000110838 1.10650069769824e-09 62.676663365374 21.7477442965257 2.88198456404451 0.0042241259541812 -162.979349846801 43.0966119947021 -3.78172070386498 0.000186431988758812 WDR37 other 1.33424166910174e-05 1 1 2.88198456404451 -3.78172070386498 1.81551285477211e-10 93.24581771579 36.3407803658382 2.56587274068129 0.0107466737639932 -259.815480586177 52.2770726115446 -4.96996996210535 1.09311167867645e-06 YTHDC2 other 2.254503863056e-06 0.0163693473881798 1 2.56587274068129 -4.96996996210535 5.804520797866e-12 208.50856932746 30.2883206447996 6.88412447070616 3.30055884653147e-11 -273.71927196465 140.799743958258 -1.94403245538428 0.0528078748953467 ATP6V1H essential 7.51221081659818e-08 1 4.52440606682534e-07 6.88412447070616 -1.94403245538428 1.21813391580918e-08 423.17760689784 90.1588451075594 4.69368930350638 3.99860424415646e-06 -373.119967735472 190.511935421394 -1.95851229430937 0.0510465270387335 POLR2B essential 0.000140755373971751 1 0.0460599222884383 4.69368930350638 -1.95851229430937 0.153159849886111 -16.2922165612915 33.7084631869564 -0.483327183174457 0.629197100310365 -128.798674114542 66.6869458756563 -1.93139260500396 0.0543257593850241 FAM214A other 1 1 1 -0.483327183174457 -1.93139260500396 1.77812164685534e-12 342.416124208303 66.891623073712 5.11896869105677 5.34703163940732e-07 -286.010523080017 132.09865067986 -2.16512827048599 0.0311259703472395 ARAP2 other 2.32827248439239e-08 1 0.00645547129825646 5.11896869105677 -2.16512827048599 0.000145030024460335 489.681393875396 117.617105822091 4.16335183945178 4.04908311928965e-05 -407.556815205912 381.095819957323 -1.06943396873666 0.285690377852085 TPR essential 1 1 0.43531692615483 4.16335183945178 -1.06943396873666 4.67971295532975e-07 402.425405431889 166.702149522127 2.41403849071828 0.0163431238414138 5205.66434213607 1025.84994863574 5.07448906056778 6.63203115944882e-07 CP other 0.00495721993358081 0.00995666837968051 1 2.41403849071828 5.07448906056778 6.2730007273889e-05 59.4420912578713 21.1097712715062 2.81585671835799 0.00516749471114193 -181.27886779729 73.5600785845523 -2.46436479249981 0.0142524602493436 KIAA0556 other 0.552839554104784 1 1 2.81585671835799 -2.46436479249981 3.29559476090194e-05 58.7175718037785 14.7939293147153 3.96903152331362 8.91979094250203e-05 -20.2797339659408 35.0196252743096 -0.579096258371959 0.562932908289581 DTNBP1 other 0.299668431608814 1 0.929709809936987 3.96903152331362 -0.579096258371959 0.105256765633393 2.52891064676741 1.350092063915 1.87313940608915 0.0619605912782465 -5.31318710458341 7.46529296354464 -0.711718499264444 0.477157628670528 ANO2 other 1 1 1 1.87313940608915 -0.711718499264444 1.74416880334849e-07 54.4522455891753 10.7890034204046 5.04701346986256 7.58980464119196e-07 -99.0245727418829 53.0318035138554 -1.86726768053459 0.0627899199750341 C12orf4 other 0.00189817890868417 1 0.00909334494061209 5.04701346986256 -1.86726768053459 0.0132788077295674 20.5312866693956 11.1158358992414 1.84703038579372 0.0656715648614409 -18.0579342338654 20.8721028915378 -0.865170813295802 0.387597240967691 FAM184B other 1 1 1 1.84703038579372 -0.865170813295802 7.47119466284069e-12 2841.28745142206 534.802213146602 5.31278177534989 2.02660436300513e-07 -1231.78515557315 769.978108293982 -1.59976646388347 0.110637200780724 MAP4 other 9.64157671239591e-08 1 0.00249272336649631 5.31278177534989 -1.59976646388347 2.23036554097354e-05 111.851139617789 43.2912777779072 2.58368764700381 0.0102195132607248 -318.887104786395 100.981000762203 -3.15789210227111 0.00174109506891708 GOPC other 0.206308812540052 1 1 2.58368764700381 -3.15789210227111 0.0205138229424468 77.9484717433231 28.0213300795312 2.78175488180208 0.00572830291535549 68.6184764186781 65.3624032220902 1.04981568969434 0.294597530013451 ROS1 og 1 1 1 2.78175488180208 1.04981568969434 3.00734811094397e-10 146.353517700801 33.1120608950071 4.41994589720235 1.35495022295087e-05 -69.9545819145818 60.6834401310113 -1.15277877726699 0.249864284230784 USP28 other 3.70956389484939e-06 1 0.150643365787678 4.41994589720235 -1.15277877726699 0.000401886068480596 50.0556384566192 15.2873095204499 3.27432622396109 0.00117546528820725 -109.085159815365 64.9591573454096 -1.67928840633388 0.0940749746202153 HDAC9 other 1 1 1 3.27432622396109 -1.67928840633388 2.75940522254985e-09 231.938374980424 64.057562899056 3.6207805055887 0.000341356927228438 -370.609740385742 97.5394121553433 -3.79958964480431 0.000173460909281814 TSPAN17 other 3.2825884527453e-05 1 1 3.6207805055887 -3.79958964480431 5.20911226409643e-12 308.905973679053 50.7476732809918 6.08709628850625 3.28730647004895e-09 -157.791576745134 77.2726590906927 -2.04201044201079 0.0419700509815687 NOP16 essential 6.75100949426898e-08 1 4.31393228064524e-05 6.08709628850625 -2.04201044201079 0.0180062243530008 35.8727318684194 16.9736329029399 2.11343865356049 0.0353393694636656 87.8724357378758 31.6717318273259 2.77447523921192 0.00585493730755135 CC2D2A other 1 1 1 2.11343865356049 2.77447523921192 0.00090624877512784 76.769169931078 20.7265983324286 3.70389625445511 0.000250141888960594 109.468424475328 118.435175591244 0.924289797594743 0.356034082805245 RRM2B other 1 1 1 3.70389625445511 0.924289797594743 1.38980194503544e-10 74.1710936808628 16.3349786526991 4.54062997312868 7.96897095703219e-06 -102.059764753593 37.8584251221831 -2.69582700347962 0.0073950574363446 ZNF800 other 1.73002546118012e-06 1 0.0900812476982919 4.54062997312868 -2.69582700347962 0.0141375710204023 -11.9808166591462 4.16291360808096 -2.87798830028307 0.00427136374356767 -17.2641325943037 13.5075266340872 -1.27811205278221 0.20213623382155 TNFRSF17 other 1 1 1 -2.87798830028307 -1.27811205278221 1.95099370583522e-05 176.012179172026 46.71361489853 3.7678989209967 0.000195949050041315 -282.036999970814 151.57302236384 -1.86073349711141 0.0636988714180734 SNX29 other 0.181247315272092 1 1 3.7678989209967 -1.86073349711141 0.70211536900093 3.33890984419583 12.8592911850815 0.259649602465602 0.795303151653138 -36.7290231307256 50.1522434229371 -0.732350551519448 0.464497462600447 LMO3 other 1 1 1 0.259649602465602 -0.732350551519448 2.34649065055407e-16 204.307962972831 26.7166023910611 7.64722849044568 2.44098924434378e-13 -243.86034525146 92.8432657461606 -2.62658086498368 0.00904097705807209 MRPS10 essential 3.28532155984075e-12 1 3.45277928612428e-09 7.64722849044568 -2.62658086498368 2.22313773811911e-20 193.412814706274 31.1467729896114 6.20972242520226 1.67452319275606e-09 -432.358434292496 100.898737276044 -4.28507279639811 2.43017261360016e-05 RSF1 other 3.2346654089633e-16 0.354027546349272 2.21455692241989e-05 6.20972242520226 -4.28507279639811 3.43504630257872e-07 453.96332936421 103.402516657425 4.39025416439524 1.54021905573462e-05 -419.420136586877 219.158882176952 -1.91377201973604 0.0565411981947661 VPS13D essential 0.00368099561784336 1 0.170610064803724 4.39025416439524 -1.91377201973604 0.0896424920698046 -82.1556803207785 43.4705773152198 -1.88991463639969 0.0596815411080453 -165.684965116937 86.8469199733622 -1.90778170564663 0.0573228140208967 CELF2 other 1 1 1 -1.88991463639969 -1.90778170564663 3.87255163688086e-13 1081.41557725326 148.249521356619 7.29456370150348 2.37458752075528e-12 -576.160688224496 282.926143670127 -2.03643495348475 0.0425296890318601 FAM120A other 5.14429759443254e-09 1 3.31706130774305e-08 7.29456370150348 -2.03643495348475 6.55603091893552e-06 137.46518885941 34.9845419052424 3.92931224401171 0.000104809678849434 -211.151676197068 90.1996908897864 -2.34093569627718 0.0198609092333375 R3HDM1 other 0.0636000559445935 1 1 3.92931224401171 -2.34093569627718 0.386912991850695 -111.870976598553 140.006081116147 -0.79904369657877 0.424863348229313 -438.58488427792 355.095006934179 -1.2351198290975 0.217700550707812 COL9A2 other 1 1 1 -0.79904369657877 -1.2351198290975 0.317393204318525 -106.269210381557 83.3081704375236 -1.27561570279895 0.203016611032418 -206.942565502472 201.57251079812 -1.02664080872481 0.305365039102398 KITLG other 1 1 1 -1.27561570279895 -1.02664080872481 4.57395037400758e-11 34.5279145842636 7.2242476176036 4.77944782791333 2.68709196877858e-06 -29.6487719609933 10.4284008198972 -2.84307943979522 0.00475611875305916 ERCC8 other 5.78513243304479e-07 1 0.0312884988844578 4.77944782791333 -2.84307943979522 0.000805370365198263 28.1366493607029 7.60014799770278 3.7021186125859 0.000251954382628333 6.91051785988438 10.6912475364382 0.646371514300062 0.518504992734388 ADAMTS6 other 1 1 1 3.7021186125859 0.646371514300062 0.16776989946701 186.951311698923 108.12912800623 1.72896346383328 0.0847800961770445 301.219961350758 244.689427828225 1.23102973440364 0.219215756149893 H6PD other 1 1 1 1.72896346383328 1.23102973440364 1.56323767750905e-19 523.255547404007 72.8957550961612 7.17813467620644 4.99112010073028e-12 -739.868877684763 165.872764854097 -4.46046027107317 1.13484805557523e-05 VAMP3 other 2.26122330051685e-15 0.166788618727892 6.93466226795465e-08 7.17813467620644 -4.46046027107317 0.00076537426450797 -9.10746173216061 64.9648815467755 -0.140190538569721 0.88859792204731 -546.227470231712 147.826228102959 -3.69506465287926 0.000258626042522292 PER3 other 1 1 1 -0.140190538569721 -3.69506465287926 0.00063327046514551 -0.370615502629147 9.79996422353691 -0.0378180464923562 0.969856337001607 -81.9490941905157 22.0476767552062 -3.71690383074781 0.000238002129667647 UTS2 other 1 1 1 -0.0378180464923562 -3.71690383074781 0.13781695976249 -28.3263589251975 14.9024375631787 -1.90078695549692 0.0582282739445902 -38.6096427085594 33.527074054871 -1.15159595034658 0.250346820391051 TNFRSF9 other 1 1 1 -1.90078695549692 -1.15159595034658 0.00278939054200526 125.469177305909 54.4993985735919 2.3022121452677 0.0219668370137518 -319.439881283318 131.462103845813 -2.42990087590548 0.0156543305210432 EPN3 other 1 1 1 2.3022121452677 -2.42990087590548 0.0865400964423636 678.260935595179 331.790874830396 2.04424228346211 0.0417477919104762 -628.311489692887 1154.34369455036 -0.544301920354514 0.586612788440229 LTBP1 other 1 1 1 2.04424228346211 -0.544301920354514 0.382013394577517 277.695767547254 215.10518077417 1.29097665871095 0.19765243965058 -117.771226871749 742.182329078997 -0.158682337556994 0.874020197561524 ELN other 1 1 1 1.29097665871095 -0.158682337556994 0.00604824016622238 67.7782166892018 36.7238881715579 1.84561657449156 0.0658802667287888 -261.982277556029 126.709271984565 -2.06758569008226 0.0394901327879562 RFC2 essential 1 1 1 1.84561657449156 -2.06758569008226 0.00233622300679311 121.019230837572 83.7561067135919 1.44490038501197 0.149467423388262 -514.247137265548 184.472652029328 -2.78766056436263 0.00562739849791146 ARID1B other 1 1 1 1.44490038501197 -2.78766056436263 2.07117447607676e-27 778.484489278926 63.7159253509697 12.2180520017682 2.22501475461651e-28 107.33414819506 379.812647480711 0.282597614658187 0.777670323055184 CLPTM1L other 3.11152541541012e-23 1 3.37156485767039e-24 12.2180520017682 0.282597614658187 4.07061480058619e-15 435.610787851262 115.749295653952 3.76339903746437 0.000199356987749367 -663.101520863295 175.333148768795 -3.7819518186929 0.000185656881064085 NEDD4L other 5.60360833448694e-11 1 1 3.76339903746437 -3.7819518186929 5.524543399971e-07 284.764064326033 86.0176142860419 3.31053199614537 0.00103754052297279 -320.493834075142 118.321188743889 -2.70867659019945 0.00711867385852169 HEXB other 0.00582286874356943 1 1 3.31053199614537 -2.70867659019945 2.71133070776885e-12 50.0514746953002 10.3178541739667 4.85095775259035 1.92451989310894e-06 -49.541254925276 14.1268356900885 -3.50688972478349 0.000518398310672213 PTCD2 other 3.53503297678902e-08 1 0.0225746183461679 4.85095775259035 -3.50688972478349 1.61773553846324e-14 148.982856566991 19.9449496706203 7.46970330972798 7.7644837535123e-13 -119.758889099456 63.0736162193866 -1.89871607619426 0.0585039997449206 JKAMP other 2.20513531247925e-10 1 1.09098761220601e-08 7.46970330972798 -1.89871607619426 2.03476525291781e-06 1161.08261494253 228.386479991198 5.08385003782744 6.3469717443518e-07 617.866183385582 476.502578011231 1.29666913023715 0.195691102997454 DKK3 other 0.0205328161671936 1 0.00763413761410634 5.08385003782744 1.29666913023715 0.0628978587850466 -154.896404813513 65.5864477277735 -2.36171358839915 0.0187950232930345 -113.692981022756 271.196718429734 -0.419226979150243 0.67533419425964 NFE2L3 other 1 1 1 -2.36171358839915 -0.419226979150243 9.35199091552565e-06 142.21022718947 32.5721173998849 4.366011132883 1.71369235635465e-05 -18.4589207750076 76.9624871750641 -0.239843090478867 0.8106064260112 MCUR1 other 0.0894798490797494 1 0.18922590998868 4.366011132883 -0.239843090478867 0.0026588177775167 746.645172009892 315.542265239566 2.36622872515358 0.0185675941594926 -1725.55900857162 860.463983018821 -2.00538202949266 0.0457665494241219 LIMA1 other 1 1 1 2.36622872515358 -2.00538202949266 0.046975122119594 78.3059577145793 34.274423070132 2.28467617250188 0.0229881195744649 -45.5019561308206 93.464203815001 -0.486838321769532 0.626707238785008 LETMD1 other 1 1 1 2.28467617250188 -0.486838321769532 0.40236192034369 -20.9053963286017 17.9891553540213 -1.16211105619967 0.246059066245693 -44.8266331924763 49.0552993124821 -0.913797975361046 0.361513153635503 SLC4A8 other 1 1 1 -1.16211105619967 -0.913797975361046 0.0895696454063683 31.6891780979466 19.7720113462105 1.60272910747748 0.109987255049712 67.9387976625439 40.5972836091481 1.67348136679851 0.0952158978628729 LAMC3 other 1 1 1 1.60272910747748 1.67348136679851 0.220622177357753 26.2822819286156 15.6404739497944 1.68040188634828 0.0938580540605462 1.3585224034298 33.4402862647742 0.0406253221839448 0.967620010628474 PTGER3 other 1 1 1 1.68040188634828 0.0406253221839448 0.831337473688279 -4.87816323350463 11.7637196834112 -0.414678636076618 0.678655899071292 -11.9214350533135 21.2255549229488 -0.561654811692304 0.574745604298724 TNIP3 other 1 1 1 -0.414678636076618 -0.561654811692304 4.97371569477134e-15 149.917237065901 25.0879068443619 5.97567736503266 6.14057790672149e-09 -152.99815291439 40.1405756992283 -3.81155851029142 0.000165804353068139 MAPK9 other 6.84035119501903e-11 1 7.99257620338869e-05 5.97567736503266 -3.81155851029142 0.183670696777895 7.28124053148998 33.9824843107859 0.21426451535737 0.830477255572135 -85.2381494966085 51.6378413957526 -1.65069157022547 0.0997826312132295 COL23A1 other 1 1 1 0.21426451535737 -1.65069157022547 1.83471591988302e-08 277.384394653308 93.6672469137945 2.96138088598456 0.00329245127010978 -872.867793925659 245.401273798535 -3.55690001284285 0.000432164040413872 BCAR1 other 0.000210551998965775 1 1 2.96138088598456 -3.55690001284285 1.69818269009543e-15 103.050580721701 20.7179716769025 4.97397053769445 1.07237057681879e-06 -153.075101916499 40.703704041154 -3.76071675839944 0.000201414915941911 FAM160A2 other 2.35266229885820e-11 1 0.0127676440876046 4.97397053769445 -3.76071675839944 0.2712938284819 -13.5821267592083 79.6529331954894 -0.170516341512172 0.864711843469117 288.081769627802 211.619926356552 1.36131684094069 0.174371358739239 HERPUD1 other 1 1 1 -0.170516341512172 1.36131684094069 0.0123233226447296 279.209589150653 115.01242049146 2.42764727459489 0.015748368033557 -253.309342366839 271.004951313124 -0.934703743010809 0.350645785484411 HOMER3 other 1 1 1 2.42764727459489 -0.934703743010809 0.00272981625813767 14.5078218714113 23.8644563023133 0.607925933347369 0.54366915131256 -136.813471785937 47.6464604505467 -2.87142991299299 0.00435955938895327 RAD51 essential 1 1 1 0.607925933347369 -2.87142991299299 2.69312130431103e-12 134.756269491666 18.2060255362836 7.40174011198127 1.20341790191703e-12 -31.1226618338293 71.337333608252 -0.436274531996654 0.662932670213794 POLQ other 3.51156086869115e-08 1 1.68767326564844e-08 7.40174011198127 -0.436274531996654 2.87179791663244e-07 187.104733291016 33.590913313265 5.57009961432422 5.42659551964302e-08 -16.5272154607268 152.538116464209 -0.108348102387934 0.913787898481017 PIK3CB other 0.00308804429975487 1 0.000682774248281485 5.57009961432422 -0.108348102387934 0.27264896925799 -161.296192813851 116.912322247457 -1.37963381201556 0.168662691676488 -409.624803665601 297.464042745518 -1.37705653390866 0.169457299001213 CYBA other 1 1 1 -1.37963381201556 -1.37705653390866 0.000573835322972655 126.926645699477 104.099378852981 1.21928341069868 0.223634613595185 -486.494063455134 158.510435919281 -3.06916109739849 0.00233025571660969 THOC3 essential 1 1 1 1.21928341069868 -3.06916109739849 0.00237555288134016 170.40508258401 72.8105139016935 2.34039115304262 0.0198834305600066 -349.23034565107 169.447923153193 -2.06098923582168 0.0401194208202807 HEBP2 other 1 1 1 2.34039115304262 -2.06098923582168 0.20694142196371 14.909515223327 16.8746432194385 0.88354550845568 0.377606986524317 -60.418828124634 43.5005793485074 -1.38892007944504 0.16582593260091 MPHOSPH9 other 1 1 1 0.88354550845568 -1.38892007944504 1.52206434633271e-12 247.404805776892 34.0605652121662 7.26367293777383 3.04773087590977e-12 -187.800756349601 138.983135247889 -1.35124852389207 0.177597966920581 PLEKHA5 other 1.99740504169241e-08 1 4.25006070645617e-08 7.26367293777383 -1.35124852389207 0.0218454656065976 103.462494113425 173.359008548218 0.596810601190349 0.551068041821577 -1451.06789182159 595.96636267393 -2.43481508807151 0.0154614487381268 PRSS8 other 1 1 1 0.596810601190349 -2.43481508807151 5.11709904370453e-13 56.8763110017112 28.8578473860662 1.97091315373625 0.0495980153151083 -306.507977895393 52.618510776006 -5.82509792419212 1.39405819434719e-08 SIKE1 other 6.78220307252598e-09 0.000211687736811621 1 1.97091315373625 -5.82509792419212 3.58332635496863e-10 355.030312366595 79.48538869593 4.46661101104704 1.1034972121715e-05 -366.318374497874 145.57599095333 -2.51633783908303 0.0123469760482237 RRP12 essential 4.40713308397592e-06 1 0.123382023292896 4.46661101104704 -2.51633783908303 2.37969213279294e-07 174.929090989209 39.3911815059695 4.44081858683774 1.23931038789462e-05 -88.4008856459205 67.4657338709848 -1.31030792335217 0.19104030108694 FNIP2 other 0.00257197125712261 1 0.138141146613866 4.44081858683774 -1.31030792335217 0.00474279733037043 145.770245770413 181.402515965635 0.803573450976985 0.422247404280248 -791.438176625847 308.852229670071 -2.5625140458636 0.0108548570456261 MSMO1 other 1 1 1 0.803573450976985 -2.5625140458636 1.64455686880409e-09 137.463606917394 42.9971159292321 3.19704249800479 0.0015327026198244 -370.020336816088 102.878879729445 -3.59665985661178 0.000375324985270247 TTC17 other 1.97050804020106e-05 1 1 3.19704249800479 -3.59665985661178 0.0313983025605249 19.0042033139671 7.70223779961306 2.46736127972079 0.0141531017594796 5.14566819734607 18.2235963703287 0.282362937193019 0.77785426666005 ALX4 other 1 1 1 2.46736127972079 0.282362937193019 0.22330612367383 -94.0400466594261 60.7968016791598 -1.54679266116168 0.122904712937351 -119.018695949479 90.9879265715067 -1.30807130609733 0.191790910351619 FSTL4 other 1 1 1 -1.54679266116168 -1.30807130609733 1.8354314763208e-05 295.42121438985 65.6768757967789 4.49810090394615 9.6239281943272e-06 -30.4083174484656 192.955105064407 -0.157592707579909 0.874877767741659 FOXN3 other 0.171025504963572 1 0.108192200760626 4.49810090394615 -0.157592707579909 4.00297673508104e-05 60.0978708667299 35.3974451449748 1.6978025001689 0.0905172129968956 -240.982639065839 68.6402943719487 -3.51080427714952 0.000510896607650892 AKR7A2 other 0.361108531271661 1 1 1.6978025001689 -3.51080427714952 1.01383034486402e-06 160.960293154314 69.4958784509125 2.31611279319257 0.0211836856401001 -524.013774622182 134.761634207518 -3.88844924376071 0.00012270087850983 MRTO4 essential 0.0104951717300323 1 1 2.31611279319257 -3.88844924376071 0.140575385450851 3.40610126290681 2.30237644712222 1.47938503591112 0.14003047917862 -11.9615944802167 12.0471113817478 -0.992901460041222 0.321515260162464 NNAT other 1 1 1 1.47938503591112 -0.992901460041222 0.000153803745137521 85.300914806631 27.8753506686022 3.06008400829594 0.00240055118485233 -125.443796856708 65.4074166046767 -1.91788337421874 0.0560184209249158 USE1 other 1 1 1 3.06008400829594 -1.91788337421874 6.37258327553544e-10 220.529273870784 32.9271250864397 6.69749555394995 9.79338014405815e-11 -234.73596340766 204.375345271574 -1.14855323226852 0.251614448507651 MCF2L2 other 7.76244368792971e-06 1 1.33072449397462e-06 6.69749555394995 -1.14855323226852 0.00208550439629425 5.95984270437591 1.7466525482625 3.41215126632055 0.000728933934152827 -3.79401831206325 8.55027446498054 -0.443730587550429 0.657542987394502 NRIP2 other 1 1 1 3.41215126632055 -0.443730587550429 0.341615491746359 1568.43596251113 1593.58142855843 0.984220783703506 0.325856657023132 -1828.80628088775 3464.83839066718 -0.527818638183467 0.598043238964095 LAMA3 other 1 1 1 0.984220783703506 -0.527818638183467 2.12529112557766e-05 86.2947437381653 22.9773727813426 3.7556401490877 0.000205472601444119 -137.442565445261 70.9662538176391 -1.93673130610001 0.0536610368857991 AP5M1 other 0.196929475696026 1 1 3.7556401490877 -1.93673130610001 3.38522015740132e-14 57.84651283402 17.2464777208089 3.35410590907063 0.000893765317318142 -144.01388904335 32.219563368152 -4.46976538439696 1.09488823540548e-05 ANAPC4 essential 4.58663479126305e-10 0.161003315016375 1 3.35410590907063 -4.46976538439696 0.101967560635898 -31.1907671735549 34.9675780338919 -0.8919910650753 0.373067956264365 -136.975697359828 64.7909329833293 -2.11411830410086 0.0352784108007861 KCNQ1 other 1 1 1 -0.8919910650753 -2.11411830410086 3.89912062482024e-08 94.0718349212879 46.0138944259836 2.04442236621829 0.0417350563172291 -563.948979331605 109.292808312095 -5.1599825097476 4.35686358047893e-07 TRAPPC3 essential 0.000439586859242234 0.0065544655704725 1 2.04442236621829 -5.1599825097476 0.0247881373308157 217.9048278454 94.0904023858881 2.31590919286027 0.0211989406116129 -222.594499464219 223.484763466614 -0.996016444304365 0.31999943787102 THRAP3 other 1 1 1 2.31590919286027 -0.996016444304365 4.02752992031029e-07 466.74947104677 98.4727484852689 4.73988467090054 3.22661763945758e-06 -465.607760101814 205.454830301155 -2.26622931872338 0.0241069333044019 PHPT1 other 0.00428408357623406 1 0.0373900452060344 4.73988467090054 -2.26622931872338 0.03380917138192 41.3237097346528 17.1918545381862 2.40367958226179 0.0168012009229234 -25.905649514504 36.1723831493385 -0.716172042288502 0.474409061238376 ENTPD2 other 1 1 1 2.40367958226179 -0.716172042288502 0.144493453516946 -45.4416632879238 67.9741550278708 -0.668513838374185 0.504289095339006 -361.45538842037 185.460421907764 -1.94896239694815 0.052176217076921 LY75 other 1 1 1 -0.668513838374185 -1.94896239694815 2.30682861042843e-08 268.76157573226 44.179844049598 6.08335274860948 3.35686726454926e-09 23.9798234878845 141.878017653044 0.169017187331487 0.86588990888889 ARID4B other 0.000263255281022092 1 4.40353847763572e-05 6.08335274860948 0.169017187331487 0.00232756530504383 122.930748492879 35.0725813624811 3.50503851491194 0.000522094807195418 -45.7163894246497 110.873871761675 -0.412327888421879 0.680376935411736 OPN3 other 1 1 1 3.50503851491194 -0.412327888421879 1.44649986270388e-07 160.60643793644 28.2084748781044 5.6935526869304 2.8371656885258e-08 61.4694224739912 92.5255445406926 0.664350831752815 0.506948742119623 SDCCAG8 other 0.00158247084979805 1 0.000360915847237367 5.6935526869304 0.664350831752815 0.718443841838991 7.50476715498489 26.2119093918603 0.286311349653734 0.774824935525008 -24.9689410442774 46.0086086024073 -0.542701503104595 0.587713108864738 PTPRN other 1 1 1 0.286311349653734 -0.542701503104595 0.00186724924831849 42.024439088151 11.7426534720281 3.57878559460659 0.000398653121201949 5.95850071750346 39.6284351232007 0.150359223092688 0.88057594062148 HHAT other 1 1 1 3.57878559460659 0.150359223092688 3.50081140253125e-07 532.673565318393 102.282101022204 5.20788642386957 3.4318130078095e-07 -69.4222859549463 215.891389275953 -0.321561161784968 0.747995765656783 KIF1B other 0.00374971909325122 1 0.00417788915570729 5.20788642386957 -0.321561161784968 0.198486657111727 51.9465394138186 50.1571761736039 1.03567511922963 0.301148141555635 -103.262752160344 112.15881948318 -0.920683301020563 0.357920343772626 FOXC1 other 1 1 1 1.03567511922963 -0.920683301020563 3.00129446914581e-11 165.391767303462 29.4499919608226 5.61602079632085 4.25525460455416e-08 -229.97130127276 76.7963522198525 -2.99456021836036 0.0029634359868837 TBC1D22A other 3.81614591751889e-07 1 0.000537481209101236 5.61602079632085 -2.99456021836036 0.00070063274029275 497.853200215043 158.195549462338 3.14707462951459 0.00180679804427871 -741.628071175293 523.884944245199 -1.41563157964735 0.157871339573889 SYNE2 other 1 1 1 3.14707462951459 -1.41563157964735 0.203151555646514 -7.96651023407491 20.7991177826518 -0.383021545304178 0.701960500903694 -117.833214259281 65.8659723612071 -1.78898466135271 0.0745719551414323 PLEKHH1 other 1 1 1 -0.383021545304178 -1.78898466135271 1.78842727181332e-05 301.528030982707 63.9645159007522 4.71398910374871 3.63038258568016e-06 148.671454307797 294.859915364643 0.504210462530792 0.614460467206227 ATP9A other 0.166892761307688 1 0.0419309188646059 4.71398910374871 0.504210462530792 0.925378107007906 1.294930828521 3.63197414235685 0.356536356748591 0.721677627392089 3.88520330582675 12.6047624905998 0.308232964224768 0.758108798064285 CHRDL2 other 1 1 1 0.356536356748591 0.308232964224768 3.20590904677772e-26 294.711203182098 30.3212779062018 9.71961683454703 1.15020358440455e-19 -235.243424162879 107.487999210332 -2.18855524236297 0.0293750614965339 FAM168A other 4.79828407031222e-22 1 1.70425665101222e-15 9.71961683454703 -2.18855524236297 2.02103700831093e-18 109.453752041886 13.7760739273113 7.94520649492828 3.61865677221714e-14 -80.1838182090399 49.0146223269007 -1.63591627156194 0.102871962456362 RELT other 2.89291237369626e-14 1 5.17576478130217e-10 7.94520649492828 -1.63591627156194 6.36178327918214e-05 80.8673278740665 20.1649508409209 4.0102913472004 7.56334220860806e-05 -42.0850165932322 58.7031433176496 -0.716912489089472 0.473954312116929 GALC other 0.55990054640082 1 0.793924031637588 4.0102913472004 -0.716912489089472 1.90147528298466e-10 385.729097664034 66.054288205262 5.83957693201372 1.29577780890913e-08 -230.675363315722 145.12776433874 -1.58946404477993 0.112952465538452 NOP58 essential 2.36049141629716e-06 1 0.000166857308453229 5.83957693201372 -1.58946404477993 2.66085421716299e-17 650.239327851319 98.5493141109083 6.59811114585266 1.72607364299872e-10 -812.437297699664 197.342080177538 -4.11689841806045 4.89183302520169e-05 SZRD1 other 3.76404437559877e-13 0.705940423866856 2.33434199479147e-06 6.59811114585266 -4.11689841806045 0.381661299618467 5.83354051929114 7.65511649960787 0.762044642898637 0.446594651253171 -10.4002114058249 17.0088568504239 -0.611458576980481 0.541330167894166 KCNH2 other 1 1 1 0.762044642898637 -0.611458576980481 8.67299366717107e-25 316.489881329633 47.3272566256513 6.68726446227385 1.03199781672051e-10 -491.097196256113 105.969983215506 -4.63430474700928 5.24478596841221e-06 CUL1 essential 1.29158221691512e-20 0.0777329728378373 1.40186583423314e-06 6.68726446227385 -4.63430474700928 2.3486548186415e-10 49.8310920121333 12.8009212266742 3.89277389726426 0.000120630899988846 -75.7484806556329 18.7576530552089 -4.03827069584262 6.74535892097112e-05 FAM114A2 other 2.90763466547818e-06 0.968768448229872 1 3.89277389726426 -4.03827069584262 0.00194532042498977 -36.286344556075 46.5967699759491 -0.778730898618171 0.436713709702865 -240.198080227654 67.7971779480471 -3.54289201258079 0.00045466095192441 CYFIP2 other 1 1 1 -0.778730898618171 -3.54289201258079 4.76229592636776e-08 145.815725026926 65.6755053225446 2.22024519355882 0.0271023709293772 -699.783493929806 143.950956907214 -4.86126323134387 1.83107165027013e-06 TAB2 other 0.00053404386518288 0.0273433929534839 1 2.22024519355882 -4.86126323134387 1.19764830671105e-08 141.19667289726 34.7370428484224 4.06472921467097 6.05750791624514e-05 -275.719096120234 76.138440558611 -3.62128635807804 0.000340716483349637 GINM1 other 0.000138472097221932 1 0.641308363092873 4.06472921467097 -3.62128635807804 0.0173998120864211 286.606582329898 109.907092347574 2.60771690168568 0.00954338413857595 -275.145706650656 376.547465902079 -0.730706568404334 0.465494729578838 EIF2AK2 other 1 1 1 2.60771690168568 -0.730706568404334 2.49656594747166e-17 266.328874341 32.4958245085733 8.19578756251392 6.1174336164657e-15 -198.930878859858 76.3045378723722 -2.60706485363415 0.00956118899596618 USP36 essential 3.53363944205139e-13 1 8.80910440771062e-11 8.19578756251392 -2.60706485363415 2.87861896298389e-12 353.595698606774 72.555990135296 4.87341841724467 1.73633401166331e-06 -407.43551128499 161.273468936559 -2.52636415630933 0.0120115078631943 KMT2C other 3.75112837066431e-08 1 0.0204227606451839 4.87341841724467 -2.52636415630933 0.0760690499358376 -26.0251815847857 12.5746217570032 -2.06965919832073 0.0392889843217787 -41.5503186158964 26.6346298819116 -1.56001111335564 0.119748752880418 MCOLN3 other 1 1 1 -2.06965919832073 -1.56001111335564 0.939981923818432 0.853991558961733 4.60291746316063 0.185532668312356 0.852928803064132 -4.93451116043197 18.2266554478354 -0.27073047902587 0.786772871296497 CCDC85A other 1 1 1 0.185532668312356 -0.27073047902587 2.54706848369615e-07 509.929710565166 103.0370247612 4.94899490495757 1.21186162719496e-06 -573.682130053622 334.160941110321 -1.71678391899257 0.0869923892581196 PUM2 other 0.00274854160075651 1 0.0143932805461945 4.94899490495757 -1.71678391899257 6.80014368253261e-09 48.8468481109851 36.997179750832 1.32028572015375 0.187683211860459 -332.489775224378 67.7625246462623 -4.90669107976806 1.47759888668005e-06 MRPL43 essential 7.9541280654584e-05 0.02208862575698 1 1.32028572015375 -4.90669107976806 0.657989827029399 5.84958863397486 34.0440939217827 0.171823889553779 0.863684592494909 41.7868241348949 49.1116908446248 0.850852890956174 0.395487293113575 ITIH4 other 1 1 1 0.171823889553779 0.850852890956174 5.31199620184842e-05 10.8205662504698 17.9826525680068 0.601722477234579 0.547786280406309 -116.621349229549 30.7254651450211 -3.79559263559095 0.000176252551516906 HPF1 other 0.47239582223038 1 1 0.601722477234579 -3.79559263559095 0.000774128189041375 155.178823290955 40.6995679377993 3.81278797672036 0.000165203386587918 189.472598670645 263.644666013553 0.71866653528619 0.472877461300962 ZFR other 1 1 1 3.81278797672036 0.71866653528619 0.235874796897227 -65.6709618438282 58.2484607977677 -1.12742827783605 0.260414088272084 -163.100249538964 116.683133690101 -1.39780484446144 0.163149030738179 TRAF1 other 1 1 1 -1.12742827783605 -1.39780484446144 2.55162177515193e-09 292.331843672819 49.6107832500132 5.89250611504386 9.63803436464767e-09 -191.67252887632 99.149459540695 -1.93316766187364 0.0540974966233526 RC3H2 other 3.04025734509353e-05 1 0.000124552318094342 5.89250611504386 -1.93316766187364 0.000307922140566384 -23.2027472726611 40.7324098335458 -0.569638461546464 0.569322596370542 -217.860447886885 58.7601926988487 -3.70761969763169 0.000246520706129214 IL17RB other 1 1 1 -0.569638461546464 -3.70761969763169 5.91387621032308e-09 252.837515169914 58.7685281491966 4.3022604637644 2.25085046199881e-05 -470.220964098634 134.587703650679 -3.49378844681894 0.000543518073897076 TRAF3IP2 other 6.94052512043517e-05 1 0.246491125409928 4.3022604637644 -3.49378844681894 0.00583770475060551 157.500449855203 89.2093110969034 1.76551581800826 0.0784337449743549 -797.84590226565 373.128339316839 -2.13826133851539 0.0332549816629873 DCBLD2 other 1 1 1 1.76551581800826 -2.13826133851539 0.0190594073725192 -692.147079664119 974.379764239246 -0.710346319850472 0.478010008155577 -4123.67856458812 1581.04034651414 -2.60820577645596 0.00953141394801565 SERPINB3 other 1 1 1 -0.710346319850472 -2.60820577645596 0.258183913340763 57.9283894750613 41.8674956815944 1.38361247865436 0.167441539040897 -124.063642683618 131.517377420659 -0.943325096019819 0.346226290202199 SOAT1 other 1 1 1 1.38361247865436 -0.943325096019819 0.119161991563735 85.8476889237403 47.3791578043916 1.81192939895996 0.0709708954938572 -207.608988680382 277.282098351349 -0.748728424643258 0.454592294644668 PKP2 other 1 1 1 1.81192939895996 -0.748728424643258 2.0139774776455e-30 1266.94576069576 149.344475414762 8.4833788272193 8.30888285342154e-16 -1415.72342364009 306.068134168157 -4.62551721526906 5.43877141569821e-06 GDI2 other 3.04553674169552e-26 0.0805808372949846 1.20437256960345e-11 8.4833788272193 -4.62551721526906 0.04666882940385 62.2829293859786 88.114991665955 0.706836920805644 0.480183813915399 -421.641290513856 199.804329941324 -2.1102710368573 0.0356132517410294 PRDM1 other 1 1 1 0.706836920805644 -2.1102710368573 1.50204911897465e-06 37.0017216733901 20.4924504064592 1.80562699625844 0.0719192212264632 -200.27346865305 46.4674653530085 -4.30997187239704 2.17795883883638e-05 ATG5 other 0.0153404276520881 0.317698855821063 1 1.80562699625844 -4.30997187239704 1.46041773438005e-09 115.052223225726 46.3616024710395 2.48162740486796 0.0135914092862333 -465.7066155453 90.1515856010027 -5.16581724481749 4.21903537710741e-07 PITHD1 other 1.75337753189668e-05 0.00634880443547122 1 2.48162740486796 -5.16581724481749 9.65278626854142e-09 127.341986151494 21.064000286851 6.04547970078534 4.15910759040152e-09 -51.961107280957 74.7900109328005 -0.694759990443705 0.487711437019048 MTA3 other 0.000112155723654183 1 5.44094454976327e-05 6.04547970078534 -0.694759990443705 1.96618796537624e-06 149.795302710008 28.7160095959516 5.21643866323009 3.34277188912323e-07 36.4503172952451 192.644883913121 0.189209890005091 0.850052134615443 USP13 other 0.0198801265179191 1 0.00407116188376319 5.21643866323009 0.189209890005091 5.75155952354772e-18 740.137337620581 78.2941827944135 9.45328645378481 8.04520575366443e-19 205.170728831726 508.557134804863 0.403436929285146 0.686902285059541 ATP11B other 8.19769778891256e-14 1 1.18763327335594e-14 9.45328645378481 0.403436929285146 0.222620295226054 -988.26274146611 3461.29616166852 -0.285518110934985 0.775431951721142 -19958.9912974398 11689.8359706521 -1.70737992796031 0.0887214108197024 LAMC2 other 1 1 1 -0.285518110934985 -1.70737992796031 0.00103717444620367 70.4576728415068 23.2419152930165 3.03149168014897 0.00263543186241861 -147.72538956344 100.31399216769 -1.47262995292316 0.141849297679044 CDK14 other 1 1 1 3.03149168014897 -1.47262995292316 1.43500085013008e-13 1665.53881700621 209.491513298535 7.95038801706846 3.22195423393416e-14 137.29986023688 842.252008185986 0.163015177052046 0.870609382351718 SEC61A1 essential 1.9229011391743e-09 1 4.609972117913e-10 7.95038801706846 0.163015177052046 0.00287327563818326 154.231979417469 55.1699914589359 2.79557736622575 0.00549566075954361 -185.016758076991 129.116557457816 -1.43294370388893 0.152856278370265 PPP1R12A essential 1 1 1 2.79557736622575 -1.43294370388893 0.814434781013209 3.2730120779917 5.12941083378058 0.638087332844688 0.523873182011987 1.83010576339856 10.0038806303634 0.182939584249325 0.854961272336865 RASGRF1 other 1 1 1 0.638087332844688 0.182939584249325 0.166667749733493 24.5376310742384 13.8307968367444 1.77412996256651 0.0769924752266559 -18.1184611910202 55.4653519090087 -0.326662692427223 0.744136573959975 CAMK2B other 1 1 1 1.77412996256651 -0.326662692427223 0.0762897141703289 -193.474279641438 85.6149402252138 -2.25981912891015 0.0245045566100454 -165.063672275436 166.753593489101 -0.989865758342562 0.322987614190214 CROCC other 1 1 1 -2.25981912891015 -0.989865758342562 0.26224236056263 294.216166927195 202.039253224702 1.45623269850426 0.146308732516051 -500.283248859205 686.131759926594 -0.729135827953406 0.466451897271206 ATP2B4 other 1 1 1 1.45623269850426 -0.729135827953406 6.16193083546817e-05 376.652795541029 86.8514236461109 4.33674866488956 1.94026091870392e-05 -299.298954205022 294.950209958261 -1.01474399440969 0.310994494904008 ZC3H11A other 0.543913634846775 1 0.213448103666619 4.33674866488956 -1.01474399440969 1.43618466898428e-16 107.953243956712 14.8498975826581 7.26962885473238 2.78266337282074e-12 -43.1324222509384 21.1378385798882 -2.0405313479864 0.0421179009811373 RIOK2 essential 2.01496709058495e-12 1 3.88292847043406e-08 7.26962885473238 -2.0405313479864 2.80355053503764e-09 41.9314142730664 18.4661652739653 2.27071585523951 0.0238347650026251 -239.866307325765 44.4476238724547 -5.39660585713372 1.33236596718275e-07 YIPF1 other 3.33370194121326e-05 0.00201213908363939 1 2.27071585523951 -5.39660585713372 0.000239551716340574 105.080076024174 44.7039822042218 2.35057529202063 0.0193549309445811 -301.136064613804 108.168399585557 -2.78395599609124 0.00569152618486777 NDC1 other 1 1 1 2.35057529202063 -2.78395599609124 3.6939411134891e-08 39.7907798751352 7.43002180255013 5.355405533464 1.63661825827489e-07 109.80633806402 46.0964636435698 2.38209895911044 0.0178000481775579 DGKG other 0.00041697207289065 1 0.00201975059253704 5.355405533464 2.38209895911044 0.00105427543097402 91.2342758746386 46.5474136174762 1.96002889922943 0.0508626726123114 -335.513705050407 133.262987122837 -2.51768110781685 0.0123024656468803 FLYWCH1 other 1 1 1 1.96002889922943 -2.51768110781685 0.018469987629226 53.4194696875303 19.4010836894246 2.7534271045204 0.00623440490587338 7.00860837516267 53.9209891030659 0.1299792250058 0.896664528860142 UNKL other 1 1 1 2.7534271045204 0.1299792250058 0.351836324666959 -7.94359856609098 12.6040922896906 -0.630239638326703 0.528987593147737 -40.1398222697922 27.7357786032207 -1.44722175800506 0.148813728880556 TBXAS1 other 1 1 1 -0.630239638326703 -1.44722175800506 0.000125287154968518 84.3252366480475 91.3739673932453 0.922858436091953 0.356776280401936 -664.491076451275 201.071848052865 -3.30474446266873 0.00105847276377223 PARP12 other 1 1 1 0.922858436091953 -3.30474446266873 1.81500991863327e-05 308.979396624766 83.8524313333607 3.68479949491743 0.000268696372789652 -147.805019467157 153.574147217136 -0.962434251763597 0.33655820777322 ALDH18A1 other 0.169249674912553 1 1 3.68479949491743 -0.962434251763597 2.72011934572446e-06 158.278533910315 35.2353581569741 4.49203703862416 9.86521963782662e-06 268.299510474905 113.153925147275 2.37110210826272 0.0183269942878547 TARBP1 other 0.0272202342926647 1 0.110796281752431 4.49203703862416 2.37110210826272 1.1604578118341e-13 102.438876948893 18.6685751076223 5.48723597587625 8.34856585062971e-08 -98.8147015379365 31.9106087532948 -3.09660972944409 0.00213178752626931 GATB other 1.55745042926255e-09 1 0.00104256890342664 5.48723597587625 -3.09660972944409 0.0391516049808693 401.52846686999 158.840591692029 2.52787063176206 0.0119565423747566 -267.46499025375 682.981153364689 -0.391614012972526 0.695604083137805 MXD1 other 1 1 1 2.52787063176206 -0.391614012972526 4.97748926852421e-06 109.032696928052 24.6179184432095 4.42899740607951 1.30123572730216e-05 -96.6318087096819 59.9134655456306 -1.61285627245325 0.10776145362662 CDK17 other 0.0488042822778799 1 0.14486657352055 4.42899740607951 -1.61285627245325 9.32127668476911e-08 32.7094044354408 5.67470291874547 5.76407345085688 1.93212728362952e-08 -4.42023173987867 11.3316447144347 -0.390078567698828 0.696737964881095 DNAJC25 other 0.00103111962686916 1 0.000247582790124286 5.76407345085688 -0.390078567698828 5.41169057262943e-10 483.376612684211 71.9417005760167 6.719004538591 8.3830466807239e-11 634.96788031689 386.403611043007 1.64327625873615 0.101307938520691 SLC2A3 other 6.61362704881043e-06 1 1.14051350091249e-06 6.719004538591 1.64327625873615 0.0894870860060238 24.1053123447703 14.3558048479582 1.67913346552624 0.0941021318539473 -14.3725802299485 26.3746858483246 -0.544938442588558 0.586175432831077 PSD other 1 1 1 1.67913346552624 -0.544938442588558 5.1927199253682e-35 152.287974371114 25.7352240225349 5.91749169301049 8.64924373533745e-09 -240.292716117788 38.0243267849056 -6.31944695502607 9.11918279263085e-10 CTDP1 other 7.89916555047011e-31 1.3920432532951e-05 0.000111921213935267 5.91749169301049 -6.31944695502607 2.33626855959584e-26 2066.30330025593 177.704066007145 11.6277772742287 2.63231771144564e-26 -548.077270890399 931.083406489073 -0.588644655323724 0.556514930477538 YBX3 other 3.49832854113882e-22 1 3.97637913490978e-22 11.6277772742287 -0.588644655323724 0.00107620451037013 21.8066454133176 6.39959751626183 3.40750263714326 0.000739348236758567 -29.8283822010688 33.5307975190646 -0.889581650544077 0.374358822836739 STYK1 other 1 1 1 3.40750263714326 -0.889581650544077 3.10079823736669e-18 1627.92583082572 177.03394521131 9.19555754622429 5.85284527844548e-18 -1104.76348310511 865.461503071951 -1.27650216581992 0.202742826136095 WNK1 essential 4.43011044172579e-14 1 8.5937327223415e-14 9.19555754622429 -1.27650216581992 0.044551257548187 65.6667970340355 55.0490334100325 1.1928782935191 0.233800762702286 -179.705591477821 115.306127399357 -1.55850860254304 0.120101141750971 CCAR1 essential 1 1 1 1.1928782935191 -1.55850860254304 0.000273990844177484 145.401325950848 52.8658469036788 2.750382987636 0.0062912494634989 -568.179985726687 240.941507791273 -2.35816564333489 0.0189666952543828 OGFR other 1 1 1 2.750382987636 -2.35816564333489 0.00676158967545164 13.1833704225438 153.273967486068 0.086011803822734 0.931511163327449 -736.336766637402 267.972262269978 -2.74780964417711 0.00634183497896818 GNA15 other 1 1 1 0.086011803822734 -2.74780964417711 3.72882166782617e-05 41.1945638120575 14.7019664545004 2.80197645257498 0.00538846644377519 -79.3489696275035 28.8390130612984 -2.75144539304602 0.00627135752285695 PIGV other 0.33719734342152 1 1 2.80197645257498 -2.75144539304602 0.437634081340417 37.3555560339262 82.5052137151105 0.452766005345001 0.651025018826173 -181.312220311554 169.283039167974 -1.07105957692338 0.28495231584302 PTPRU other 1 1 1 0.452766005345001 -1.07105957692338 4.83635168488362e-05 26.4152227472002 39.7270939589347 0.664917065781486 0.506583940363701 -340.743857466935 81.3196096940193 -4.19018068026948 3.61254879270023e-05 SNRNP40 essential 0.432321477111747 0.523747323965679 1 0.664917065781486 -4.19018068026948 0.031825767176523 17.5952304314536 7.15762891296227 2.45824848499607 0.0144944994571975 -8.08680059090191 17.5050269765552 -0.461970187291496 0.644418584900195 RIMBP2 other 1 1 1 2.45824848499607 -0.461970187291496 0.00324763229981083 633.384949141474 283.009520713499 2.23803406876433 0.0259064594556106 1849.36716783786 572.621518108647 3.22965014298846 0.00136813111795448 COL11A1 other 1 1 1 2.23803406876433 3.22965014298846 5.02226187925087e-09 200.62021134811 55.8742775975701 3.59056474596522 0.000381901537517475 -539.022864828383 150.009729628019 -3.59325269210872 0.000378134568502395 QSER1 other 5.91371336281789e-05 1 1 3.59056474596522 -3.59325269210872 0.22185038103528 -10.5450369763448 25.9034638463124 -0.407089840915081 0.684215881807331 -104.108254949631 59.8504350062423 -1.73947365526705 0.0829190739641709 MPC1 other 1 1 1 -0.407089840915081 -1.73947365526705 6.17234876130054e-19 77.927518341564 52.0562121330474 1.49698787423091 0.135382079180237 -551.202608799951 74.5673876013766 -7.3920064324444 1.27323440917081e-12 ACAA1 other 8.87954092800696e-15 1.95123173205426e-08 1 1.49698787423091 -7.3920064324444 4.64849051332581e-09 573.382545773337 91.0527062574926 6.29725978876278 1.02052749647982e-09 59.0317761559102 424.014609256206 0.139221090187109 0.889364693156554 BCAT1 other 5.4815000133138e-05 1 1.3580159395657e-05 6.29725978876278 0.139221090187109 0.0042391318210299 119.154070380746 58.6911832526729 2.03018688288789 0.0431695678436141 -337.016550417417 152.310635374626 -2.21269217076329 0.0276289030931532 HDAC7 other 1 1 1 2.03018688288789 -2.21269217076329 0.035847051301943 -19.3098124391542 28.9447948156626 -0.667125559608571 0.505174204053952 -126.748649386426 53.5143811414065 -2.36849696629221 0.0184561408955482 LZTS1 other 1 1 1 -0.667125559608571 -2.36849696629221 0.457140881085228 2.41291666666666 4.886873293031 0.493754702031591 0.62181814791755 9.02166666666666 7.20170801078254 1.25271208623833 0.211225175665412 PRDM6 other 1 1 1 0.493754702031591 1.25271208623833 0.00272752410965959 17.1704110156331 4.98841654931481 3.44205638119607 0.000655538832482111 4.08642046734833 28.6198106148575 0.142782931806926 0.886553194855739 SPAG4 other 1 1 1 3.44205638119607 0.142782931806926 2.60121149635442e-28 1822.25962323873 151.104681244899 12.059584178503 8.07071294658065e-28 -784.291479477228 529.020550337497 -1.48253499599756 0.139191426888488 NCKAP1 other 3.91690427121048e-24 1 1.22222876863017e-23 12.059584178503 -1.48253499599756 1.52838285159824e-26 324.856895602681 28.0530552097065 11.5800896969781 4.00701768053612e-26 -168.161373597169 146.882778909111 -1.14486786569598 0.253122136840328 MRPS35 essential 2.29058737969029e-22 1 6.04939459230538e-22 11.5800896969781 -1.14486786569598 0.46389798440631 17.5783396183624 27.1615639556568 0.64717700523653 0.517982818480879 -31.5714010943741 46.4554545268848 -0.67960590238339 0.497246873711399 GUCY1B3 other 1 1 1 0.64717700523653 -0.67960590238339 0.000133013927964426 97.8763489838826 26.6212318654608 3.67662734311219 0.000277354784829096 -86.1603045908638 64.0535783379923 -1.34512866925593 0.179542153639537 SFSWAP essential 1 1 1 3.67662734311219 -1.34512866925593 1.14511943923005e-13 321.614740581978 39.7959140192141 8.08160205660051 1.32433444868241e-14 -96.316388422251 244.266851259563 -0.394308060736015 0.693616259950587 TNK2 other 1.53697931133458e-09 1 1.90121453452847e-10 8.08160205660051 -0.394308060736015 8.87434710468491e-07 142.50068590822 29.4665374898868 4.83601732837215 2.06694029401764e-06 -169.301443978415 99.0091484054088 -1.70995758174975 0.0882491454276847 MON2 other 0.0092239963806095 1 0.0242100716638286 4.83601732837215 -1.70995758174975 1.42701341465752e-07 1573.99834951705 696.518417412398 2.25980865712717 0.024507329467067 -7421.19892279765 1876.3358194196 -3.9551549599971 9.42783476944524e-05 CDH3 other 0.00156158077965972 1 1 2.25980865712717 -3.9551549599971 9.21883539456669e-16 317.840870845394 62.2463552650717 5.10617640971735 5.67355929695344e-07 -475.801857633591 103.434342820403 -4.60003751809727 6.10798924446205e-06 GPBP1 other 1.28151030819872e-11 0.0904104567965272 0.00684174515619615 5.10617640971735 -4.60003751809727 1.64584413419401e-05 122.939504176154 30.5995095620337 4.01769524857651 7.35082565540932e-05 -33.8836101817118 94.7578924464303 -0.357580875924053 0.720895700512709 DGAT2 other 0.154149761608611 1 0.772865809409735 4.01769524857651 -0.357580875924053 1.88582976057178e-08 15.2264960928047 2.70507349233415 5.62886595722991 3.98608989859917e-08 -17.2669655529388 11.2271497603336 -1.53796519344066 0.125051520500176 ZNF112 other 0.000216304673537583 1 0.000503961345879893 5.62886595722991 -1.53796519344066 3.36691319035134e-05 461.12325902944 126.254031594647 3.65234482578688 0.000303488341035321 -743.97952748698 360.718926244282 -2.0624909683368 0.0399677625083343 CS other 0.305783055947709 1 1 3.65234482578688 -2.0624909683368 0.425797989333463 -7.35675387777109 7.68128449054618 -0.957750476085802 0.338916166808737 6.4933468080922 15.3380316668047 0.423349419870177 0.67232651740323 LTK other 1 1 1 -0.957750476085802 0.423349419870177 0.00210327830583871 196.839634029606 56.7331870822895 3.46956771076685 0.000592750645083046 -13.113982283842 227.515899740416 -0.0576398497810673 0.954071481925208 MRPS24 essential 1 1 1 3.46956771076685 -0.0576398497810673 3.69043747189227e-12 119.823350883089 17.1569156867327 6.98396804361216 1.6667600031133e-11 -89.6610077293603 77.9992483969511 -1.14951117571109 0.251203666127343 ELMO2 other 4.79830680095433e-08 1 2.29579522828825e-07 6.98396804361216 -1.14951117571109 5.71583623095347e-11 274.090107124279 52.3325320824802 5.23747077042424 2.97267225067208e-07 -224.644161430899 103.507054473964 -2.17032706198209 0.030724200706504 WAPL other 7.2099558217247e-07 1 0.00362993008529567 5.23747077042424 -2.17032706198209 7.2752640074044e-05 108.327186835618 26.1163522768698 4.1478681895235 4.33106036922392e-05 -66.5725994565697 60.0209602281755 -1.10915585494613 0.268217150143285 APPBP2 other 0.636876611208181 1 0.464679467014034 4.1478681895235 -1.10915585494613 0.00270713875997037 31.0370696437269 74.8948584722107 0.414408549222949 0.678852580562792 -582.611575132054 178.062010151752 -3.27195887901932 0.00118464952219368 POLD1 other 1 1 1 0.414408549222949 -3.27195887901932 0.801159607827207 -12.9735732150027 26.8625926504786 -0.482960575838967 0.629459213467075 -43.9271415367373 84.9741089192958 -0.516947363089822 0.605555669401519 SEZ6 other 1 1 1 -0.482960575838967 -0.516947363089822 1.82277574199583e-06 993.731929071606 199.512664664482 4.9807962353806 1.03785791202609e-06 -310.250847074769 539.104110865366 -0.57549338026148 0.565362118790119 EIF4B essential 0.0184665410421598 1 0.0123629634480547 4.9807962353806 -0.57549338026148 0.126871718594223 2.33324506317621 2.74040690381619 0.851422852543181 0.395171193543133 -10.3060956848503 6.37937151293937 -1.61553464380406 0.107180425432588 SLC6A16 other 1 1 1 0.851422852543181 -1.61553464380406 4.10933142485655e-08 65.500228008573 14.4329768896154 4.53823410856429 8.05443847493513e-06 -89.2750923434722 32.9857352073579 -2.70647574723629 0.00716726871220262 BICRA other 0.000462464158553356 1 0.0910151547667669 4.53823410856429 -2.70647574723629 3.59369120114422e-05 33.4695703124998 16.1676008845467 2.07016307190578 0.0392389492788014 -131.052113095239 37.0420863741804 -3.53792472085445 0.000462969147485236 SPHK2 other 0.325516548999644 1 1 2.07016307190578 -3.53792472085445 0.0131764155524314 2139.69332031249 1011.38550131491 2.11560608445609 0.03515058203993 -3587.43211309525 2317.21634921786 -1.54816450967391 0.122571076508785 RPL18 essential 1 1 1 2.11560608445609 -1.54816450967391 0.0611292694537778 25.7635937499999 22.9877136084824 1.12075494713372 0.263232574465403 -94.261547619048 52.6678558625369 -1.78973580897371 0.0744418442629504 CA11 other 1 1 1 1.12075494713372 -1.78973580897371 0.0148954761645173 168.519162431364 72.6908095165598 2.31830080793052 0.0210629733824486 -223.50044784306 197.51363548232 -1.13156971313541 0.258662653393899 ISOC2 other 1 1 1 2.31830080793052 -1.13156971313541 1.03853139901853e-06 491.658301035781 107.123707991152 4.58963109339335 6.38653954374251e-06 -417.428335494515 294.418948856812 -1.41780390533738 0.15722102906781 U2AF2 essential 0.0107425687914477 1 0.072672433468246 4.58963109339335 -1.41780390533738 8.1721557369216e-06 494.50606020831 118.082845556738 4.18778915664514 3.64595306938022e-05 -441.147305684608 324.539057868567 -1.35930420388188 0.175007352115247 EPN1 other 0.0786243103449227 1 0.393544174308901 4.18778915664514 -1.35930420388188 8.29059589477506e-20 240.34036031362 29.0842698978161 8.26358582003347 3.83561967028438e-15 -310.723655441498 91.2136879985061 -3.40654634473926 0.000742124370370061 MED29 other 1.20155606302975e-15 1 5.5340320602863e-11 8.26358582003347 -3.40654634473926 0.00130558922005841 33.1335160532498 9.04852693640277 3.66175801720297 0.000293407012887109 43.4318715740016 52.7066840440941 0.824029672169601 0.410542248977418 AHRR other 1 1 1 3.66175801720297 0.824029672169601 3.45343228982819e-09 4368.94264980802 744.526630541077 5.86808110091769 1.10107873179916e-08 415.515969754324 1348.3874852068 0.308157687840447 0.758162839428546 GPC1 other 4.09266260667539e-05 1 0.000142116231913317 5.86808110091769 0.308157687840447 1.18026547599665e-05 26.9154832805916 6.01263036562061 4.47649059461407 1.05654590629361e-05 -16.0334679918666 19.4054318690654 -0.826236081734715 0.409285785489411 ADCK1 other 0.111900969779242 1 0.118312010586759 4.47649059461407 -0.826236081734715 0.132587333829904 28.6710357162819 24.0861514443203 1.19035354330311 0.234789775694414 -84.2573081437596 68.6967527883286 -1.22651078433615 0.220908229811297 HAGH other 1 1 1 1.19035354330311 -1.22651078433615 3.63169418442377e-21 282.097471061195 51.9986240580251 5.42509491686555 1.14481788819649e-07 -424.004669654218 96.1710121297441 -4.40886146734313 1.42062112298428e-05 RNF4 essential 5.31171591413821e-17 0.208390912530564 0.00142209278071768 5.42509491686555 -4.40886146734313 6.14036248621097e-09 110.137754506509 23.1375717918423 4.76012588949981 2.94613175723071e-06 -144.009814408636 56.6353910233189 -2.54275307023733 0.0114734711399016 CASP8 other 7.19782324282352e-05 1 0.0342016435696913 4.76012588949981 -2.54275307023733 0.338553006638849 141.375945684262 101.988590043038 1.38619374603183 0.16665588288534 227.229541420259 195.308511579737 1.16343901032439 0.245520930553391 LIMCH1 other 1 1 1 1.38619374603183 1.16343901032439 3.27159631301915e-30 199.080370670919 16.1146375464152 12.3540085898616 6.21623685466163e-29 -154.586918698679 82.8439603337909 -1.86600107087861 0.0629559119182597 INTS13 other 4.94599930602234e-26 1 9.42692319009436e-25 12.3540085898616 -1.86600107087861 1.40990330804581e-05 285.429931733449 63.6834797944472 4.48200903365737 1.03116085784015e-05 -309.193382854483 327.391271371326 -0.944415474363081 0.345669888404479 TM7SF3 other 0.132855188717157 1 0.115562197338145 4.48200903365737 -0.944415474363081 0.0867125096791891 64.6684826787045 29.2779546837444 2.20877733356864 0.0279006923189425 25.1468528223134 69.8341824222316 0.360093752802466 0.71901531629484 DLX3 other 1 1 1 2.20877733356864 0.360093752802466 0.00122239034042215 0.907378059131948 13.8132863547797 0.0656887894616025 0.947666745234417 -72.3267975859181 25.5788340938523 -2.82760337396697 0.00498617674107174 SPA17 other 1 1 1 0.0656887894616025 -2.82760337396697 0.032251879943788 -4.12372668426882 1.90985257392205 -2.1591858662684 0.0315785611801569 0.0121987053913556 3.50963513554021 0.00347577594828185 0.997228903397066 TSPAN32 other 1 1 1 -2.1591858662684 0.00347577594828185 0.907502224921246 -1.58280394157683 14.5119974474904 -0.109068648013754 0.913216617385184 -28.5343390271235 64.7546284712554 -0.440653273762352 0.659762490958807 WISP2 other 1 1 1 -0.109068648013754 -0.440653273762352 0.227509645968203 9.18765387536972 5.36517161036925 1.71246225518915 0.0877987444078295 1.56171491013037 17.1254862986714 0.0911924416564755 0.927397827379538 DMRT3 other 1 1 1 1.71246225518915 0.0911924416564755 0.149628637477331 -3.00989681446285 5.29006484219474 -0.568971629696339 0.56977575866559 -43.2430913321834 22.1263126592515 -1.95437405220352 0.051530358893007 ST3GAL6 other 1 1 1 -0.568971629696339 -1.95437405220352 0.0402324812796965 58.923964483295 40.5091942691611 1.45458248544214 0.146765042660333 -125.222008860641 104.126882265985 -1.20259059078298 0.230023858857805 ATP2C2 other 1 1 1 1.45458248544214 -1.20259059078298 0.48198525903831 9.31437961326652 150.639469517814 0.0618322650967983 0.950735252747631 -431.79901382909 359.29118369964 -1.20180798588719 0.230332156818596 NGFR other 1 1 1 0.0618322650967983 -1.20180798588719 0.997341826822211 -1.34140163489011 22.2604687551767 -0.0602593615454826 0.951986801488861 -0.262193019872258 41.2846985093834 -0.00635085223675947 0.994936756829769 CDON other 1 1 1 -0.0602593615454826 -0.00635085223675947 1.03187134025935e-08 161.847592453898 25.9255521249301 6.24278286047626 1.36907406589041e-09 66.6299158038135 143.289097531717 0.465003387916969 0.642246280998126 TAF2 essential 0.000119655800616474 1 1.81552911877727e-05 6.24278286047626 0.465003387916969 1.22043988102566e-08 371.911229508818 81.2562376546016 4.57701759574092 6.75857003780483e-06 -290.861687867343 178.80740365271 -1.62667586422915 0.104790234673823 HIPK2 ts 0.000140997419454894 1 0.0767976313395762 4.57701759574092 -1.62667586422915 9.76769578147744e-21 333.626218991061 47.4089572501949 7.03719799679183 1.1985247343371e-11 -383.609438997837 108.34006457117 -3.54079020089413 0.000458159194780632 TNPO3 essential 1.42510681451756e-16 1 1.656121477907e-07 7.03719799679183 -3.54079020089413 0.0025772922717988 143.366566071324 78.7214460330133 1.82118816784947 0.069514840823454 -426.916875653761 186.380991043715 -2.29056017603013 0.0226409129787775 RFXANK other 1 1 1 1.82118816784947 -2.29056017603013 4.34323439541903e-10 167.273743859859 35.680756609093 4.68806605455308 4.09291956598118e-06 -276.561723742261 84.0602635993269 -3.29004111931521 0.00111379109022094 TMEM161A other 5.32567401566282e-06 1 0.0471299688022733 4.68806605455308 -3.29004111931521 4.07752692968934e-06 82.3928959007329 23.9896040349462 3.43452504596196 0.000672300634989501 -138.200893771244 54.5673222441654 -2.53266768621803 0.011800434954117 LPAR2 other 0.0402207256344556 1 1 3.43452504596196 -2.53266768621803 8.16234473413387e-10 505.882928942161 94.3876942036503 5.35962800246684 1.59883199565893e-07 -1114.7358431724 429.107966736649 -2.59779805919224 0.00981609269021688 CTSA other 9.90908650723852e-06 1 0.00197500097375769 5.35962800246684 -2.59779805919224 2.91765269552011e-06 191.450798293405 54.4876498423065 3.51365490799265 0.0005056485932072 -326.975034357138 128.389810679424 -2.54673663452593 0.0113415187848941 SUGP2 other 0.0291240092066818 1 1 3.51365490799265 -2.54673663452593 0.657588636244595 -24.6213437316554 113.997117849988 -0.215982159865264 0.829139261535506 -153.100886358255 168.845926147831 -0.906749069114111 0.365221781967642 SLC12A2 other 1 1 1 -0.215982159865264 -0.906749069114111 2.44173630758955e-07 55.5766666666664 14.6674711749641 3.78911033836087 0.000180612448178582 -51.8028070175438 21.6152206788945 -2.39658931949398 0.0171219687852124 SNX24 other 0.00263707521219671 1 1 3.78911033836087 -2.39658931949398 0.672245902069418 -46.0154743703702 59.8010633144697 -0.769475855778573 0.44217847564315 70.4329300516952 276.652769890589 0.254589643470947 0.79920358695312 EYA2 other 1 1 1 -0.769475855778573 0.254589643470947 1.31273733879696e-11 701.054723370055 269.366070972993 2.60260960423758 0.00968501376409694 -2033.17329324717 442.021882333855 -4.5997118570513 6.11694676142596e-06 CNN2 other 1.68319181580546e-07 0.0905369290158656 1 2.60260960423758 -4.5997118570513 9.45960640888833e-07 -19.0352865779004 44.6061797734916 -0.426741018275064 0.669856726832319 -353.813156330203 73.1974427067983 -4.83368193267962 2.08966362524425e-06 ABCA7 other 0.00981528760986253 0.0311736019613937 1 -0.426741018275064 -4.83368193267962 0.257828194633713 1.31483090108841 30.2589001136706 0.0434526997395514 0.965367854959855 -67.0933105000168 44.6397582805782 -1.50299448483366 0.133829763132651 SNCAIP other 1 1 1 0.0434526997395514 -1.50299448483366 3.4310435199713e-11 40.9853793056345 16.839209730965 2.4339253421298 0.0154828485736031 -153.044275446767 30.8594615052972 -4.95939552997373 1.14981989277136e-06 DDX20 essential 4.35399422684357e-07 0.0172128037947873 1 2.4339253421298 -4.95939552997373 8.02596868286997e-07 248.298447230335 55.5702275598088 4.46819201816472 1.10135870229588e-05 -147.993935150197 109.610756308837 -1.35017711886972 0.177928485643408 BTBD1 other 0.0083638619644188 1 0.123153930090726 4.46819201816472 -1.35017711886972 4.6213888901445e-07 35.8876545426161 6.7323064338669 5.33066266295948 1.85864807314669e-07 -23.330016170758 36.8050735144367 -0.63388043938037 0.526614526966943 FAR2 other 0.00489636152910809 1 0.00228929683169478 5.33066266295948 -0.63388043938037 0.55515949283363 -12.3868776616767 24.7337124712137 -0.50080947921155 0.616849500711945 93.0938950534626 114.016033158624 0.816498280763255 0.414822611909224 BCAS1 other 1 1 1 -0.50080947921155 0.816498280763255 0.0728360666510935 366.754598786457 189.550741880844 1.93486237588565 0.0538882475561683 -86.348985626147 350.476180964557 -0.24637618850018 0.805549002701436 CHI3L2 other 1 1 1 1.93486237588565 -0.24637618850018 1.01685394919645e-05 -173.913087709084 184.730027039873 -0.94144460700775 0.347191680970595 -1397.32641945471 304.290794382137 -4.59207588679106 6.33063559897578e-06 SBNO2 other 0.0969976982138496 0.0936490924156487 1 -0.94144460700775 -4.59207588679106 0.000124419419977883 40.5853855369149 11.3673770955572 3.57033862743738 0.000412876982597626 -47.1124204891202 28.7690180454947 -1.63760961234817 0.102514516942194 PMS1 other 1 1 1 3.57033862743738 -1.63760961234817 2.39233139895054e-11 372.804304935546 82.9746392450132 4.49299097082789 9.8537513530934e-06 -430.384984434957 147.389873867715 -2.92004445855782 0.00375062321722112 HMG20B other 3.04902636796247e-07 1 0.110677335197945 4.49299097082789 -2.92004445855782 0.349450671920418 30.7157675206367 21.5738398097631 1.42375060682227 0.155502203399452 34.1103069046255 71.5622169030301 0.476652462441827 0.633938011770926 CALCRL other 1 1 1 1.42375060682227 0.476652462441827 2.85777614345624e-15 147.459316820783 20.0862016136293 7.34132414167971 1.77256699655462e-12 -70.9317117001475 46.568414785124 -1.52317213346086 0.128706332245496 TAF11 other 3.94401685558395e-11 1 2.48088476837784e-08 7.34132414167971 -1.52317213346086 7.56899793866861e-14 353.799223742263 46.7076943572828 7.57475248159189 3.92356231473382e-13 -2.83154696959978 108.288432344065 -0.0261481943020757 0.979155486345167 ANKS1A other 1.01961971231805e-09 1 5.53496935739500e-09 7.57475248159189 -0.0261481943020757 1.01908963385972e-17 602.28649762666 132.297079920131 4.55253054708589 7.55719189681647e-06 -1129.56218390483 226.951137216019 -4.97711620995176 1.05945057651005e-06 AP3D1 other 1.44934927727529e-13 0.015869510185544 0.0855474122719624 4.55253054708589 -4.97711620995176 0.0056564182051216 62.6259725251541 21.4261750881723 2.92287224702671 0.00371524837386912 -13.6983105730325 49.5788050909924 -0.276293681299737 0.782500866769751 ZNF76 other 1 1 1 2.92287224702671 -0.276293681299737 0.0413848055646724 110.521282523387 51.7429025534961 2.13596990252182 0.0334428635752411 -104.718827577228 146.994612230013 -0.712399087208494 0.476738403634584 SLC9A3R2 other 1 1 1 2.13596990252182 -0.712399087208494 0.0352776325896345 67.388362067362 28.0092821912475 2.40592963458449 0.0166999596579006 -21.4389451170751 79.5705956055853 -0.269433010447018 0.787770679745437 NTHL1 other 1 1 1 2.40592963458449 -0.269433010447018 5.67152382800237e-07 184.671165900612 34.5050952285919 5.35199699282639 1.66516148801183e-07 67.6735553986694 79.9975833019099 0.845944997404112 0.398217528631947 UHRF1BP1 other 0.0059738160480349 1 0.00205464276005779 5.35199699282639 0.845944997404112 5.21807852904921e-27 1003.993257537 87.682199379908 11.4503658055715 1.32971538333449e-25 -243.610897957099 204.000584501709 -1.19416764688269 0.233313719600284 IPO5 other 7.83077044854416e-23 1 2.00560971268341e-21 11.4503658055715 -1.19416764688269 0.120662491061626 106.329540895242 121.212131673151 0.877218636678705 0.381025986476405 -317.06965562772 241.253205609077 -1.31426090205613 0.189699687417976 OAT other 1 1 1 0.877218636678705 -1.31426090205613 1.91709660048251e-10 237.752522328991 54.0158538008775 4.40153224654071 1.47360156560055e-05 -285.639295162872 99.3912897855837 -2.87388659287026 0.00433016676469189 WDR3 essential 2.37950030051889e-06 1 0.163422413625101 4.40153224654071 -2.87388659287026 0.00768707049254726 86.9130664038224 53.3077486778693 1.63040211900572 0.104000374622497 -233.244823366044 115.600229578323 -2.01768477637852 0.0444584711243852 PKN2 other 1 1 1 1.63040211900572 -2.01768477637852 2.7308987774498e-09 166.392695898376 72.1664037871826 2.3056808593243 0.0217716126244261 -477.443258340987 118.422968149072 -4.03167785610623 6.93742318825607e-05 WDR18 essential 3.24922336540977e-05 0.995797724442276 1 2.3056808593243 -4.03167785610623 9.58820452125182e-10 419.265239774223 68.3920734601395 6.13031918119254 2.59583847276643e-09 -126.087244629723 183.343557877815 -0.687710253303533 0.492136553357345 TRAM2 other 1.15988510093583e-05 1 3.41664259785517e-05 6.13031918119254 -0.687710253303533 0.141311054402687 189.548299073308 104.344594951639 1.8165607826755 0.0702257488245594 -135.805870918341 194.590283287578 -0.697906743460761 0.48574550183866 NTN1 other 1 1 1 1.8165607826755 -0.697906743460761 2.58847317955646e-09 79.7140693900664 24.0279388253444 3.31755753040228 0.00101332728190598 -154.711056583674 49.183221182928 -3.14560642557864 0.0018140804690434 MCM10 other 3.08338925148765e-05 1 1 3.31755753040228 -3.14560642557864 4.66734195713388e-05 232.829916028732 99.8722572940864 2.33127719686094 0.0203593699590927 -961.877663546447 285.343865520118 -3.37094215007272 0.000840876179895582 DGKA other 0.418053819100482 1 1 2.33127719686094 -3.37094215007272 0.30911278047629 123.995194415405 145.235661127883 0.85375171257853 0.393881207532642 -451.459660790765 414.951119364093 -1.08798275199889 0.277421472117174 ERBB3 other 1 1 1 0.85375171257853 -1.08798275199889 0.0785274354498309 -11.4248004460617 5.92015871336442 -1.92981320251954 0.0545277270584692 -23.2074920765348 14.4597969082109 -1.60496666888569 0.109503192832693 ANKRD44 other 1 1 1 -1.92981320251954 -1.60496666888569 1.01901401473205e-21 560.713827975375 94.612959034821 5.92639564067552 8.02893090037058e-09 -1330.76457782461 247.878969757296 -5.36860621587862 1.53049359244536e-07 KARS essential 1.49581067222517e-17 0.00231043312715551 0.000104054944468803 5.92639564067552 -5.36860621587862 2.633229497435e-05 54.2667017899628 14.7546366787302 3.6779422612413 0.0002758527087943 -38.369805231383 38.6560591316124 -0.992594850415177 0.321659739218989 ADAT1 other 0.241809464749456 1 1 3.6779422612413 -0.992594850415177 5.94219931354111e-13 105.181440460839 14.3474207149467 7.33103479368001 1.88175336157075e-12 -1.67794050120779 33.3518700760016 -0.0503102373985066 0.959906553868504 TBC1D22B other 7.86331235160895e-09 1 2.63182025149285e-08 7.33103479368001 -0.0503102373985066 1.25552260026871e-15 467.631598161263 56.0536962918805 8.34256488147064 2.22006195735009e-15 -247.413268935195 220.880968910735 -1.1201203533075 0.263505089540295 NDUFB4 essential 1.74216316013286e-11 1 3.20909955934955e-11 8.34256488147064 -1.1201203533075 0.00451761842667444 402.007099772088 134.921578149195 2.97956120352783 0.00310754090078786 -103.476321380372 272.852976256462 -0.379238382516713 0.704762375242776 SPEN other 1 1 1 2.97956120352783 -0.379238382516713 0.0489760622558261 324.425772382502 131.463160823038 2.46780748577322 0.0141170797512942 230.813788431613 515.296256228472 0.447924442768075 0.654510821371487 MYLK other 1 1 1 2.46780748577322 0.447924442768075 8.21712127368663e-31 530.113190326645 41.1485267446856 12.8829202954419 8.53695214555582e-31 -156.242903897537 138.597703532667 -1.12731235738484 0.260468413176995 ZC3H15 other 1.24325044870879e-26 1 1.29821431277467e-26 12.8829202954419 -1.12731235738484 1.56946607220971e-13 190.223765215073 23.8504950426695 7.97567366525329 2.73847911625271e-14 -29.1083955809604 44.0303891526339 -0.661097849488781 0.509026736114075 MAP2K4 other 2.10198591051047e-09 1 3.91958515909251e-10 7.97567366525329 -0.661097849488781 0.00269700895294792 44.3064999020678 12.9645116632944 3.41752169713496 0.000713592274980951 29.0700262085304 43.7518922428109 0.664429004514817 0.506894262977565 TMEM206 other 1 1 1 3.41752169713496 0.664429004514817 1.65734746382847e-07 519.420230308513 177.409117785374 2.92781023203609 0.00365828808764945 -1034.5827147285 326.479048293437 -3.16890998101239 0.00167790317495223 SLK other 0.00180667447031942 1 1 2.92781023203609 -3.16890998101239 0.0013377290586066 -4.57421952647126 24.1011055841012 -0.189792933378489 0.849592864208182 -186.680628700056 51.9886536066274 -3.59079560152829 0.000381919844169847 CYB5R4 other 1 1 1 -0.189792933378489 -3.59079560152829 6.18819229977876e-05 142.906881153111 32.5888213188872 4.3851503481744 1.57467318937008e-05 68.6419124406374 60.9559579563197 1.12609029112175 0.260971104761257 GSTO2 other 0.54598420660948 1 0.174278171756965 4.3851503481744 1.12609029112175 4.60531854053242e-15 56.6110383787258 8.96061355911278 6.3177636224646 8.94481952654937e-10 -33.2600975650324 18.3416414456545 -1.81336537755253 0.070718087381643 SEC61A2 other 6.33737884362667e-11 1 1.19198665010797e-05 6.3177636224646 -1.81336537755253 0.110663589365945 -1.05192139444109 21.0041922761013 -0.0500814970941766 0.960088689378378 -80.1365128504237 42.9814168671986 -1.86444558349541 0.0631745514227937 PRKCQ other 1 1 1 -0.0500814970941766 -1.86444558349541 0.0275427834074453 82.9577406065695 52.1295414145515 1.59137675788977 0.112521501354799 -104.772859556891 91.1853655484117 -1.14900959081274 0.25141823873893 TLE2 other 1 1 1 1.59137675788977 -1.14900959081274 1.64435777944239e-06 37.6944531565393 21.315885015005 1.76837382684345 0.0779541322542576 -140.559755589546 38.5681838302501 -3.64444839321941 0.000312719594935347 ASB1 other 0.0167346291213852 1 1 1.76837382684345 -3.64444839321941 0.0449590200216895 -14.1104713485527 65.417014250817 -0.215700326744529 0.829358767127338 -306.593091419368 135.731100987176 -2.25882711618419 0.024566928999751 FAM107B other 1 1 1 -0.215700326744529 -2.25882711618419 0.00565619497279953 97.0671139091583 125.224821874004 0.775142758891867 0.438836801950776 -747.371837907975 262.713694866376 -2.84481491643635 0.00473463492630283 ME1 other 1 1 1 0.775142758891867 -2.84481491643635 0.00543387060422691 111.132745820918 55.7358765603575 1.9939176106896 0.0470094494726099 -135.377989947345 114.595611889921 -1.1813540476348 0.23833932524015 TBC1D1 other 1 1 1 1.9939176106896 -1.1813540476348 4.11110164144769e-10 192.28998665851 31.4975177509061 6.10492509851758 2.97490091920101e-09 -245.889612713019 131.07446464599 -1.87595359154908 0.0615718126650355 CDK13 other 5.04555504454874e-06 1 3.90901980783012e-05 6.10492509851758 -1.87595359154908 0.0577714881905793 180.106549683737 94.3407764291781 1.90910607799527 0.0571426514122297 -520.167190369311 390.381222848069 -1.33245955472544 0.183657278792609 MTHFD2 other 1 1 1 1.90910607799527 -1.33245955472544 8.9829934582923e-31 283.929752271844 22.3258392576717 12.7175399318652 2.87054257499823e-30 -167.933892138057 118.178604324944 -1.42101773072481 0.156285323073484 FOXJ2 other 1.35876759050129e-26 1 4.3620764969673e-26 12.7175399318652 -1.42101773072481 5.18802781361471e-26 2473.43026821149 215.876685234166 11.4576072239043 1.09332729517404e-25 -690.401240107696 671.725053488361 -1.02780332000771 0.304821046926765 YBX1 essential 7.76077080638625e-22 1 1.6496122229586e-21 11.4576072239043 -1.02780332000771 0.0388378480115491 71.8346122150388 28.0818637159715 2.55804290418883 0.0109880660158231 43.7846210679941 61.1504510632707 0.716014686836756 0.474506083467766 PDE4A other 1 1 1 2.55804290418883 0.716014686836756 2.3971388889801e-06 255.714349670029 52.5490351527332 4.8662044683941 1.7889849652151e-06 334.574720959762 177.339477427092 1.88663418779563 0.0601147105628559 PPP2R5A other 0.024084054417583 1 0.0210241513112079 4.8662044683941 1.88663418779563 1.1202112060949e-09 209.869430311989 66.7768316387639 3.14284797828233 0.00183022937896455 -495.857766298115 124.289445541821 -3.98954041621555 8.21626880518803e-05 ELAVL1 other 1.35052663006801e-05 1 1 3.14284797828233 -3.98954041621555 0.429480909937531 22.6774514112883 19.1231825685107 1.18586178477583 0.236556670239192 -18.8288623934229 59.8529832540736 -0.314585194751196 0.753281633203333 TIE1 other 1 1 1 1.18586178477583 -0.314585194751196 8.25392241311404e-06 635.351884366745 166.223319916607 3.82227887570467 0.000158971984175678 -1023.89309862906 453.280576589207 -2.25885059168768 0.0245675686944554 DIP2B other 0.0793779718469177 1 1 3.82227887570467 -2.25885059168768 4.41431499432749e-06 180.518148416123 56.1400795657157 3.21549505829992 0.00143560390755396 -484.802380705481 153.090478809341 -3.16677029476963 0.00169039243104439 SMARCD1 other 0.0434456881741712 1 1 3.21549505829992 -3.16677029476963 0.0051834799741114 140.83913669305 46.1623031663932 3.05095558567327 0.00247196995848673 -93.652922590673 145.593224460362 -0.643250556046105 0.520522211480477 KDM4A other 1 1 1 3.05095558567327 -0.643250556046105 1.02034907344475e-12 182.644447692806 28.5960579509447 6.38704985163076 5.95359537484096e-10 -287.354281457559 88.478949192632 -3.24771354180467 0.00128678961397337 NFYC other 1.34400379954142e-08 1 7.96888740922463e-06 6.38704985163076 -3.24771354180467 0.00748495585735511 33.689374479499 11.1384696349469 3.02459633896193 0.0026925225495306 80.9915922192538 66.0231649665118 1.22671477897696 0.220837292802159 SLC9A3 other 1 1 1 3.02459633896193 1.22671477897696 0.0002065910789669 142.850367042147 37.7247755798666 3.78664590700402 0.000182432856128538 9.88408847433429 65.107149543414 0.151812643367892 0.879430675166349 NGEF other 1 1 1 3.78664590700402 0.151812643367892 0.0123071779529534 157.767621111402 55.4549017583738 2.84497160952195 0.00473143119096826 180.620552308096 194.109939710432 0.930506457204312 0.352819228360934 ASPM other 1 1 1 2.84497160952195 0.930506457204312 0.99368754744394 -0.621444476249153 21.3771284067963 -0.0290705311033067 0.976826460209988 -8.07400320573922 74.8276608331788 -0.107901317719118 0.914141593231891 CD84 other 1 1 1 -0.0290705311033067 -0.107901317719118 0.0153283614690638 -75.7127896706901 32.923428872012 -2.29966295324279 0.0221148307417492 42.0311525543892 83.1452956873107 0.505514499731389 0.613547716078353 SPI1 other 1 1 1 -2.29966295324279 0.505514499731389 3.16203908840429e-08 100.070550697675 19.4217374723846 5.15250249057088 4.50524731589192e-07 -41.4158469219055 43.8436444137127 -0.944626010810181 0.345562521165945 ZNRD1 essential 0.000358259028716207 1 0.00545720607373988 5.15250249057088 -0.944626010810181 0.171348520170717 3.62795927510166 13.5308397028124 0.268125212831217 0.788776779001448 -46.4673002191344 29.8226084461785 -1.55812327090687 0.120198655911747 MPPED2 other 1 1 1 0.268125212831217 -1.55812327090687 5.83767096252375e-16 165.064343121169 20.2513227021887 8.15079318761384 8.32794123113745e-15 -99.9484152867735 82.7547363270448 -1.20776670584484 0.228031672850718 ZBTB11 essential 8.13654578756561e-12 1 1.19722483138832e-10 8.15079318761384 -1.20776670584484 6.42760491086149e-19 105.698073367714 12.3414767991986 8.56445910708008 4.69694968215939e-16 -74.332235758027 36.4025603718908 -2.04195075837096 0.0419785822107825 ATXN3 other 9.24482414329208e-15 1 6.81856185359079e-12 8.56445910708008 -2.04195075837096 6.83235416204321e-21 268.571123875096 29.0676948359375 9.23950541626888 3.55130837664596e-18 -159.554875947467 86.8713358635861 -1.83668035447292 0.0671844757481855 GOLGA5 other 9.97660354741549e-17 1 5.2239746220462e-14 9.23950541626888 -1.83668035447292 0.0752058939598576 -181.325934931181 138.967603549602 -1.30480723779957 0.192896038099856 309.582136254945 272.748594088189 1.13504576362673 0.257205603784266 FGFR2 og 1 1 1 -1.30480723779957 1.13504576362673 3.38563799202677e-05 44.58453253075 14.3598042305468 3.10481478820637 0.00207468994965108 -73.9487869315708 31.1507890591879 -2.37389771382885 0.018193132312426 LRRC40 other 0.307415929676031 1 1 3.10481478820637 -2.37389771382885 1.42437055792544e-05 33.2167144612866 28.8592426683371 1.15099051084006 0.250595445459902 -166.320149205459 42.5905875192886 -3.90509168557807 0.000114914815990382 ISOC1 other 0.134175706556577 1 1 1.15099051084006 -3.90509168557807 0.000247368193595815 113.452195651858 27.5581820393469 4.11682437868629 4.91524690004653e-05 66.4133136223706 83.0150658519066 0.800015189301272 0.424306819366642 EML1 other 1 1 0.524751759048967 4.11682437868629 0.800015189301272 0.000307729629004082 22.3732799888466 10.1276949115561 2.20911867747101 0.0278834727323324 -67.1057256187241 24.0432613856567 -2.79104088843608 0.00557341652542429 TRMT11 other 1 1 1 2.20911867747101 -2.79104088843608 2.41398866373369e-05 97.2737175597716 30.2581746432586 3.21479133181762 0.00143944792076209 -225.565094251262 93.1830912218927 -2.42066550157833 0.0160518882137454 THUMPD1 other 0.222400775589784 1 1 3.21479133181762 -2.42066550157833 1.60460556965035e-07 153.513312495139 27.0477062946861 5.67564993580614 3.09775981589275e-08 78.4962561411847 51.7786517722896 1.51599652471433 0.130507407437801 MSANTD3 other 0.00175014329481764 1 0.000393322563823903 5.67564993580614 1.51599652471433 0.105748700289638 20.5698315160502 15.4859161438142 1.32829283879771 0.185133007543805 -54.2778059592862 46.4986921090474 -1.16729747649666 0.244055796722203 KIF26A other 1 1 1 1.32829283879771 -1.16729747649666 5.75893213680409e-12 163.119879971954 23.5153716924002 6.93673406934377 2.25215422022471e-11 -58.1014997699022 69.6560458720817 -0.834119982587031 0.404839507527774 ATG2B other 7.45493765109289e-08 1 3.09558597569886e-07 6.93673406934377 -0.834119982587031 1.91023810019573e-06 245.589853360396 49.1506539155826 4.99667519748979 9.64556977565833e-07 -193.259458715744 229.515454427153 -0.842032442643567 0.400402595185995 ARFGEF1 other 0.0193277890977804 1 0.0115090938563155 4.99667519748979 -0.842032442643567 0.101603188888333 40.4848425291214 19.5942909997807 2.06615501063929 0.0396233383418722 87.4583936532286 110.784205793009 0.789448216261414 0.430438303633285 ZFAT other 1 1 1 2.06615501063929 0.789448216261414 1.38680015170355e-19 219.434363541121 22.2603499262561 9.85763315797196 3.72194279025516e-20 -34.6619870787505 104.974753470847 -0.33019355542832 0.741473207211609 MTFR1 other 2.00711585956055e-15 1 5.53155137487722e-16 9.85763315797196 -0.33019355542832 0.0183575986855199 -158.459492063897 55.7119035671906 -2.84426634018687 0.00473796774720358 -131.233349998461 241.142246710571 -0.544215506775021 0.58667217508353 STAG3 other 1 1 1 -2.84426634018687 -0.544215506775021 2.29572679975829e-13 120.982998566362 30.7549564662538 3.93377238882168 0.000102583868512929 -144.141100128273 46.7454366734439 -3.08353307586406 0.00222370434186739 FECH other 3.06548399571724e-09 1 1 3.93377238882168 -3.08353307586406 1.74281302746513e-06 129.765964412147 28.2095160863441 4.60007764808717 6.09340148653344e-06 -37.5651573487621 55.6181794783148 -0.675411487774578 0.499902126852063 MYO9A other 0.0176965234808809 1 0.0694099363331024 4.60007764808717 -0.675411487774578 1.10031550778167e-09 893.564183267822 201.380205653239 4.4371996759526 1.25784847555025e-05 -862.234654547601 405.089645073063 -2.1285033202764 0.034063830005018 PFKP other 1.32709053393547e-05 1 0.140162055630565 4.4371996759526 -2.1285033202764 1.00716208589151e-05 174.381223089431 69.4657818635104 2.51031829501413 0.0125647300998259 -331.616152514457 137.657487924326 -2.40899465415753 0.0165719885981028 IDI1 other 0.0961537643400622 1 1 2.51031829501413 -2.40899465415753 5.82247229780687e-09 290.280741559126 96.5042061825322 3.00795947702089 0.00283866136871104 -604.323516876212 168.087542894107 -3.59529032592812 0.000375134357132631 SP100 other 6.83558247762526e-05 1 1 3.00795947702089 -3.59529032592812 0.378300870325092 322.093137806581 315.135087303504 1.02207958041935 0.307520140546437 -211.918517581696 635.195348221532 -0.333627313510783 0.738880687848665 KLF6 other 1 1 1 1.02207958041935 -0.333627313510783 3.25512054734022e-10 302.532694313798 46.5062841790066 6.50520031119504 3.01106162959604e-10 42.2050737433323 78.4982229245713 0.537656422921663 0.591190318363316 PLPP1 other 4.00998300226841e-06 1 4.05379227192516e-06 6.50520031119504 0.537656422921663 0.206267116671959 44.1103972376395 110.959523374631 0.397535929283964 0.691237340747313 -318.70708151522 218.380058524178 -1.45941476373372 0.14543192108066 NEO1 other 1 1 1 0.397535929283964 -1.45941476373372 1.7292621770519e-11 636.108484316042 88.571278087253 7.18188218633811 4.92957215404985e-12 -201.96658337414 412.017673038283 -0.490189126803243 0.624339166696998 TRAM1 other 2.21103461957856e-07 1 6.85013346526767e-08 7.18188218633811 -0.490189126803243 1.92598372251305e-21 824.989459109315 82.0351670327978 10.0565341541815 7.70490416774207e-21 -567.610135151516 378.335670313453 -1.50028183882648 0.134533579115614 TNFRSF1A other 2.82156615348162e-17 1 1.14779957386854e-16 10.0565341541815 -1.50028183882648 0.0830536042302232 52.2375422523568 37.102386906109 1.4079294247173 0.160134958385083 167.786809456688 90.8842450018391 1.84615946859979 0.0658041405114127 CACNB1 other 1 1 1 1.4079294247173 1.84615946859979 0.000382677267303327 47.7437837523075 15.2770437007653 3.12519782540883 0.00193964381685692 -44.7127190064768 32.416296836813 -1.37932840483184 0.168756705575751 EVI5 other 1 1 1 3.12519782540883 -1.37932840483184 9.12987834862105e-05 31.130139188857 25.2220229168838 1.23424434635725 0.218017500735643 -170.214228886611 49.6023686141546 -3.4315746131131 0.000678875322729869 STOML1 other 0.79000837350618 1 1 1.23424434635725 -3.4315746131131 3.01720820379172e-09 11116.1610190793 2272.80866374444 4.89093569397323 1.59198974346807e-06 -9523.31363413325 4481.09353570941 -2.12522089937263 0.0343340265247708 PKM essential 3.58202957954152e-05 1 0.0187727430549755 4.89093569397323 -2.12522089937263 8.76722018899955e-17 214.41315555054 33.0129187102499 6.49482578115606 3.212585180084e-10 -192.324024996003 55.7050378519018 -3.45254275757461 0.000630731484107679 DHX29 other 1.23232046976578e-12 1 4.32092706721298e-06 6.49482578115606 -3.45254275757461 1.49287109658979e-09 248.744566269554 47.3273602831378 5.25583013253708 2.70257926646703e-07 -212.476727219311 100.741223312102 -2.10913388018971 0.0357120167445518 DNTTIP2 essential 1.79174389012707e-05 1 0.00330741650630235 5.25583013253708 -2.10913388018971 2.32736671724278e-07 40.5333333333333 7.89469332908946 5.13425052040726 4.96122708485059e-07 -26.2321839080461 25.2177431794812 -1.04022726067693 0.299029564232235 METTL22 other 0.00251658163135462 1 0.00599663517745891 5.13425052040726 -1.04022726067693 0.000234876468960179 104.082094187444 53.2882137029436 1.95319165261669 0.0516681620537784 -280.625495672788 107.892375321187 -2.60097615644653 0.00972752326065577 TP53BP1 other 1 1 1 1.95319165261669 -2.60097615644653 4.67818265157273e-10 111.418511879696 16.5067788173493 6.74986398694519 6.96123264460431e-11 -48.7579451067374 53.897858795235 -0.904636031868634 0.36633879586413 RRP15 essential 5.7317093847069e-06 1 9.48467947827337e-07 6.74986398694519 -0.904636031868634 6.62471414256734e-29 1553.61467329985 309.569669030631 5.01862691575939 8.66517712968839e-07 -3123.84398262406 437.1560508475 -7.14583265304909 6.11463814650897e-12 RHOA other 9.98543162709175e-25 9.36762564045174e-08 0.0103600857762554 5.01862691575939 -7.14583265304909 1.15969519277821e-08 256.075890014799 47.6827986628977 5.37040394430649 1.51656869578613e-07 -311.761601955896 114.917853050325 -2.71290834000674 0.00703160121257194 DHX8 essential 0.000134141942948656 1 0.00187569216294828 5.37040394430649 -2.71290834000674 3.90757672592784e-12 204.325435792016 32.5930983642649 6.26897858891618 1.1829990596071e-09 -167.533713737703 72.447023097576 -2.31249962489222 0.0213883560042126 PRKCZ other 5.079068228361e-08 1 1.57137765087611e-05 6.26897858891618 -2.31249962489222 3.12892851046226e-11 612.186200003769 85.6617213105478 7.14655496805186 6.08698308947738e-12 -378.598579932454 278.88445036171 -1.35754639400446 0.175567237948064 IARS2 essential 3.9759294582444e-07 1 8.44690643326776e-08 7.14655496805186 -1.35754639400446 0.868209953537616 4.25617780250283 17.8085791973153 0.238995921872558 0.811262697007131 -17.4336135038108 41.6781365805305 -0.418291577650683 0.676016282861859 SYT1 other 1 1 1 0.238995921872558 -0.418291577650683 0.264499392664634 24.8063613443875 22.3355988025093 1.11061993742476 0.267573680012265 -50.7301897138496 52.9024908080391 -0.958937640534319 0.338320963571166 NAV3 other 1 1 1 1.11061993742476 -0.958937640534319 0.0393056574540213 34.8698647128869 26.9100423272931 1.29579375196748 0.195983346096251 -141.395946348241 79.4882586536588 -1.77882807779602 0.0762201666352904 ROGDI other 1 1 1 1.29579375196748 -1.77882807779602 9.3586736200635e-06 330.620951840672 71.8295000852317 4.60285748123491 6.70641400446832e-06 34.7790586239545 168.932779798908 0.205875133679529 0.837060117224006 ROCK1 other 0.0895344305231476 1 0.0762251015747869 4.60285748123491 0.205875133679529 2.2954217200175e-12 243.107444098958 43.1724639991388 5.63107642185555 3.9217072620725e-08 -280.127772851851 116.302861492375 -2.40860602445466 0.0165784550056564 CBFB other 2.99850939285886e-08 1 0.000496095968652172 5.63107642185555 -2.40860602445466 6.94848936916264e-08 181.55888722638 52.9468916918455 3.42907546458185 0.000685711111722362 -168.014628433013 75.3468519885861 -2.22988252327336 0.0264552462534166 HYAL2 other 0.000772394078276119 1 1 3.42907546458185 -2.22988252327336 2.24451266965586e-06 161.166941225774 35.2025243840448 4.57827795153295 6.72776141625011e-06 -9.6225518777378 63.7744507173952 -0.150884120043282 0.880162493099932 HDAC4 other 0.0225910200200862 1 0.0764610084956825 4.57827795153295 -0.150884120043282 8.81972331513009e-24 56.6815638635398 35.7109317661132 1.58723284608681 0.113456839880875 -435.132843095886 50.8189660276174 -8.56241039731927 4.86495433516216e-16 RASSF1 other 1.30787677040064e-19 7.47062387707502e-12 1 1.58723284608681 -8.56241039731927 4.78245396198296e-05 852.013279025129 371.110158407858 2.29585005886244 0.0223347296549392 -1386.41660482044 685.143198982891 -2.02354282561456 0.0438532906841123 FGFR3 og 0.427647033280516 1 1 2.29585005886244 -2.02354282561456 0.2890994388353 -26.9357556482631 106.734493599704 -0.252362237734341 0.800923102485534 -411.314372758171 261.388500274534 -1.57357486012648 0.11657391086157 IFI35 other 1 1 1 -0.252362237734341 -1.57357486012648 2.69238677852544e-06 59.5237135747311 13.6471439502 4.36162421909961 1.75622540760474e-05 -71.8830352490969 31.3640540447373 -2.29189234103996 0.0225776151203648 HEATR6 other 0.0269480992662612 1 0.193746786966955 4.36162421909961 -2.29189234103996 2.02811443560078e-08 310.86461436923 55.9506174244918 5.55605333200759 5.81401752115461e-08 -299.410379940443 144.322514994446 -2.07459231119943 0.0388233776347924 COASY essential 0.000232137978298865 1 0.000730763862233923 5.55605333200759 -2.07459231119943 0.0560314566600469 43.5461229826792 35.0997698016952 1.24063842095557 0.215648167513474 -174.375421059897 88.8907403634233 -1.96168262686277 0.0506660729828899 PLEKHH3 other 1 1 1 1.24063842095557 -1.96168262686277 9.2034627564765e-27 452.840968419698 38.6255130668864 11.7238822856678 1.1916382432241e-26 15.979279018339 108.670391974596 0.147043538980466 0.88319025193577 MEF2A other 1.38005924033365e-22 1 1.8010420408089e-22 11.7238822856678 0.147043538980466 2.5017499374572e-08 115.929612003575 24.7674048662411 4.68073310989442 4.23730259120842e-06 -70.5945650366797 49.9780409266021 -1.41251164967341 0.158777265620183 INPP5A other 0.000284999352875124 1 0.0487247424963057 4.68073310989442 -1.41251164967341 0.000529452598861388 127.921378599307 38.6394593048377 3.31064101053018 0.00103818913475271 -143.776840218966 90.4902090167841 -1.58886626278317 0.113087422910264 PRR11 other 1 1 1 3.31064101053018 -1.58886626278317 0.187021781813696 31.6357166755585 22.4553041443385 1.40883046928289 0.159865411883923 -97.9511389222964 92.647472454042 -1.05724566820628 0.291204490510287 REEP1 other 1 1 1 1.40883046928289 -1.05724566820628 1.06947424029556e-11 262.963123207147 38.8118131604516 6.77533724384463 6.10600334725307e-11 -127.108706791353 95.1151708717681 -1.33636627707601 0.182394088081647 ATP11A other 1.37427439877979e-07 1 8.32614616431429e-07 6.77533724384463 -1.33636627707601 5.47244778231403e-09 404.597149366575 64.0386389335394 6.31801606193526 8.96357738707514e-10 -49.8525442569338 262.131746137678 -0.190181254241331 0.849288827479106 POLR1A essential 6.43122063377544e-05 1 1.19439668682776e-05 6.31801606193526 -0.190181254241331 3.57233612622677e-06 783.176955925771 174.340338003285 4.4922303403531 9.87679444375917e-06 -863.783914261613 565.405800057678 -1.52772382981125 0.127575142384768 LAPTM4A other 0.0353947063386548 1 0.110916401603416 4.4922303403531 -1.52772382981125 5.02952944871319e-06 191.500783431726 42.4578080954804 4.51037846798575 9.09629705209864e-06 -238.002292305314 154.558001422326 -1.53988981557143 0.12457544787199 TTC7A other 0.0492965329274815 1 0.102451593697787 4.51037846798575 -1.53988981557143 1.10407219520574e-20 99.6179590703234 60.4312886869579 1.64845002042498 0.100247928763965 -660.170566264231 85.2473285621154 -7.74417893674167 1.297157680441e-13 IP6K2 other 1.61017888948805e-16 1.98945073449236e-09 1 1.64845002042498 -7.74417893674167 0.0029547639614508 30.1685405786467 10.6217291850806 2.84026640605955 0.00479628533525256 -61.0761937646569 39.2183863971604 -1.55733571356416 0.120379217352548 STON1-GTF2A1L other 1 1 1 2.84026640605955 -1.55733571356416 0.00352227813184595 30.2532222571517 11.0442616492545 2.73927069259481 0.00650385167947391 -64.9860106884631 40.0439088630853 -1.62286880910297 0.105605242104648 SRBD1 essential 1 1 1 2.73927069259481 -1.62286880910297 3.215961935107e-09 107.333155235461 38.7154696024718 2.77235834506339 0.0058922350545807 -232.364904944417 55.9494231663315 -4.15312422888832 4.21487317751302e-05 KIF2A other 3.81380925884339e-05 0.609554958931932 1 2.77235834506339 -4.15312422888832 0.0323830262160361 -15.074439561716 5.82605629418832 -2.58741742278619 0.0101146476514484 -4.28500561406226 23.7744317668012 -0.180235879288012 0.857082555797366 RASGRP2 other 1 1 1 -2.58741742278619 -0.180235879288012 3.00714668417858e-08 507.98816067226 84.7761015720287 5.99211512740599 5.59160800193523e-09 0.0274596102326865 335.640894824291 8.18124687906747e-05 0.999934774231669 PSME4 other 0.000341130719853218 1 7.28754270892218e-05 5.99211512740599 8.18124687906747e-05 1.48703425802557e-11 124.735193728863 16.9841351449617 7.34421815795937 1.80520053013871e-12 -43.5186909384437 100.106858552061 -0.434722371352923 0.664063517191563 IFT80 other 1.90340385027273e-07 1 2.5260171018231e-08 7.34421815795937 -0.434722371352923 3.125441059117e-13 287.769681946669 44.1665229088196 6.51556117606905 2.8111164726339e-10 -332.005119965856 128.480204055973 -2.58409552199355 0.010206287313511 SIRT2 other 4.16027459379064e-09 1 3.78601166534334e-06 6.51556117606905 -2.58409552199355 0.00101211082317693 127.612622047274 36.6855974337607 3.47854828526893 0.000574171137030655 -134.033671088518 145.24360664744 -0.922819765925169 0.356798582372514 ERLEC1 other 1 1 1 3.47854828526893 -0.922819765925169 1.95320795749237e-07 89.4404520481614 18.1037460932918 4.9404389338681 1.26782721509281e-06 -119.185739875702 75.6815499024125 -1.57483217546926 0.116298966632082 PPP2R5B other 0.00211981659626647 1 0.0150427699070762 4.9404389338681 -1.57483217546926 0.699017775618866 510.748557766766 603.20114632467 0.84673008477981 0.39778434564972 517.686880517268 2461.48745752037 0.210314653010164 0.833557215042639 PYGM other 1 1 1 0.84673008477981 0.210314653010164 0.00195808498328379 -68.2292467475362 468.79249297951 -0.145542532718241 0.884374456889044 -2350.99654326791 697.559792898417 -3.3703154442135 0.000843023045177969 PITX1 other 1 1 1 -0.145542532718241 -3.3703154442135 5.71319268735233e-07 279.836008808047 136.986055203468 2.04280653525208 0.0418958170220651 -745.994706109133 192.591591043361 -3.87345419427569 0.000130295175291181 MAST4 other 0.00601656321905074 1 1 2.04280653525208 -3.87345419427569 0.087444323091632 1.36927882218654 18.2818949816022 0.0748980794148802 0.940342898380853 -117.864831567736 55.6249664151221 -2.11891959966547 0.0348721695184964 ADGRF5 other 1 1 1 0.0748980794148802 -2.11891959966547 0.000114987897424946 160.771274117757 60.6482201961727 2.65088198132981 0.00842878391466263 -441.300451014772 145.300762063706 -3.03715166215913 0.00258528504901392 SDK2 other 0.984296401957537 1 1 2.65088198132981 -3.03715166215913 2.63656010403923e-08 201.241234666365 33.6263586070134 5.9846276255554 5.8277815231362e-09 92.1708567174649 112.86511243738 0.816646124980411 0.414740121007183 NUP133 essential 0.000300040539839665 1 7.59243376834184e-05 5.9846276255554 0.816646124980411 8.97110642766098e-11 1890.41422323275 270.138944442099 6.99793296052484 1.52887144977251e-11 -719.113813756921 917.400487362858 -0.78386029183838 0.43370190097826 NUCKS1 other 1.12363108006454e-06 1 2.10785506780135e-07 6.99793296052484 -0.78386029183838 5.17046176122985e-20 467.154421019463 81.1627267372417 5.75577533923719 2.10070515750572e-08 -1066.31044078533 219.401770877804 -4.86008128612242 1.88055079544154e-06 VPS35 essential 7.50234001554452e-16 0.0280766233759422 0.000268638175541832 5.75577533923719 -4.86008128612242 5.72824350837741e-29 295.609809678734 40.2040885108966 7.35273004880124 1.78794377683399e-12 -647.83751656357 108.691376150171 -5.96033962867946 6.92429241953944e-09 DNAJA2 other 8.63647273758062e-25 0.000105311563408775 2.50222731567916e-08 7.35273004880124 -5.96033962867946 0.617714361905102 -15.2951546580344 34.1172514469047 -0.448311455623487 0.654232775763581 -72.1137213485239 74.2508594828887 -0.97121732799797 0.332175895187111 KCNAB2 other 1 1 1 -0.448311455623487 -0.97121732799797 0.486704989064056 12.8515324486255 11.8664147329134 1.08301730032911 0.279642398837576 33.9667414959277 48.4797397269506 0.700637868256647 0.484054568058801 ABCC9 other 1 1 1 1.08301730032911 0.700637868256647 2.13111844805574e-11 57.7354454434134 7.89137296661316 7.31627382049748 2.52718396426883e-12 81.4607537664531 91.0334239963447 0.894844444934028 0.371614904372252 GAL other 2.71866780418471e-07 1 3.52921240610142e-08 7.31627382049748 0.894844444934028 0.411888994978364 2.91229007372369 16.8411080470857 0.172927462111239 0.862818458448999 117.330224440989 88.0198078514889 1.33299796153786 0.183486680236119 CLEC2D other 1 1 1 0.172927462111239 1.33299796153786 0.473127056554056 33.2708817298062 43.0322909330131 0.773160828959766 0.439999725075223 -51.1996860237419 84.5869450887322 -0.605290638762673 0.545416260518239 RORA other 1 1 1 0.773160828959766 -0.605290638762673 0.384346772773748 -1.81827721583998 3.18227481760577 -0.571376552955281 0.568145500909617 -8.12012427994376 5.9926749630183 -1.35500829430167 0.176370675524685 DRD4 other 1 1 1 -0.571376552955281 -1.35500829430167 0.0727326525827928 -20.576857699823 46.1380518694931 -0.445984536972368 0.655910967817799 193.739006168912 97.2782337743898 1.99159666712531 0.0472677310373995 TGFBR3 other 1 1 1 -0.445984536972368 1.99159666712531 0.454065195217386 -2.80901828120612 2.87346835755037 -0.977570633003527 0.329025172847726 2.64777452675365 6.09720081018528 0.434260672919053 0.664391816733129 KIAA1107 other 1 1 1 -0.977570633003527 0.434260672919053 0.000127659907116308 634.678447295374 176.127845115205 3.60350997810842 0.000364077953020887 -410.060774136663 383.314696350181 -1.06977576920778 0.285529030376351 HES2 other 1 1 1 3.60350997810842 -1.06977576920778 6.32312790698624e-12 2586.46794059294 347.296333010385 7.44743809464755 8.96573766715424e-13 148.338777502459 1736.25055481193 0.0854362736365129 0.931968152519038 ATP1B3 other 8.17706900931461e-08 1 1.25914819797514e-08 7.44743809464755 0.0854362736365129 0.0207816771268118 96.2566296560392 37.5427473392488 2.56392076973569 0.0108074906555295 -7.45128065826865 74.1225350427903 -0.100526522115941 0.919989477444897 NEDD4 other 1 1 1 2.56392076973569 -0.100526522115941 0.00121225821415012 13.1169744042031 9.67979471377075 1.35508807697569 0.176351290355207 -51.6675201760124 19.0968920880237 -2.7055460091548 0.0071869017255387 PIGB other 1 1 1 1.35508807697569 -2.7055460091548 1.4014489387729e-09 1051.58754569095 170.27757126354 6.17572553970361 2.02293256586867e-09 -30.0750087190231 354.597861701565 -0.0848144108221801 0.932462644789503 MAPK6 other 1.68370075504176e-05 1 2.67067557345982e-05 6.17572553970361 -0.0848144108221801 7.2967663160118e-09 141.773428476708 29.5601444068014 4.79610067277234 2.49672547392345e-06 -136.420973977978 61.5991921886629 -2.21465524353233 0.0274968722672808 GNB5 other 8.52262305710179e-05 1 0.0291143157514214 4.79610067277234 -2.21465524353233 0.000251560410725562 -95.8411505305979 28.5908957366638 -3.35215627426793 0.000898586675613411 -195.701277418986 56.4058708606965 -3.46951965163879 0.000593320601831712 RAB27A other 1 1 1 -3.35215627426793 -3.46951965163879 1.2499067855081e-09 198.864747358387 32.3925307341193 6.13921613567912 2.52603826039396e-09 -58.347904728243 98.3828439557496 -0.593069913230874 0.553565388651264 HDHD5 other 1.50438780703755e-05 1 3.32603457746072e-05 6.13921613567912 -0.593069913230874 3.00233296150519e-09 334.897356424324 54.7290500825719 6.11918818103093 2.78978161401907e-09 -140.776496367965 207.501031449875 -0.678437573945128 0.497992385794562 UFD1 other 3.56497015849126e-05 1 3.66912077875788e-05 6.11918818103093 -0.678437573945128 6.7403536456185e-17 234.57448974815 26.1866759805309 8.9577802819476 2.78717916843391e-17 -9.93009003526508 119.158719460195 -0.0833349844665141 0.933637288989308 LRP6 other 9.48502565011435e-13 1 4.07680696966828e-13 8.9577802819476 -0.0833349844665141 0.751171858359047 -8.11537114845937 19.5546568797138 -0.415009641865839 0.678412948090626 -54.2116596638654 76.6004298018654 -0.707720045489161 0.479634251005117 GUCY2C other 1 1 1 -0.415009641865839 -0.707720045489161 0.274740975555035 3.12418422379275 3.42692933993409 0.911657029920796 0.362635545666461 10.3890791339259 6.45339413863282 1.60986279634345 0.108413800737487 SCT other 1 1 1 0.911657029920796 1.60986279634345 3.80574947204007e-22 410.086831464116 65.2313998834172 6.28664772175717 1.06192013852907e-09 -405.835204047749 122.83998060799 -3.30377131320835 0.00106203074738925 PHRF1 other 5.59860348857577e-18 1 1.41245997625752e-05 6.28664772175717 -3.30377131320835 8.94907675382747e-14 1028.77795435981 129.725191028486 7.93044085118287 3.74381212921843e-14 1827.30557939471 787.176346356782 2.32134208281519 0.0209001544498224 PFN2 other 1.20418776799502e-09 1 5.35402572599527e-10 7.93044085118287 2.32134208281519 0.000382092155379653 73.3160926444786 34.0182710342736 2.15519749873861 0.0318942690041981 -216.12473454792 68.1671793701136 -3.17051015672031 0.00166944571323966 PTPN3 other 1 1 1 2.15519749873861 -3.17051015672031 1.66883433510402e-05 78.4182557585961 46.4677487601569 1.6875845688878 0.092465387028641 -291.586673759609 83.9126769354898 -3.47488227534172 0.000581552301870394 DAPP1 other 0.156219582109088 1 1 1.6875845688878 -3.47488227534172 1.46025729374724e-06 925.021520777856 184.641161050907 5.00983375273955 9.02667354446764e-07 -438.862522078403 368.804281880201 -1.18996048484318 0.234944014706814 SLC44A1 other 0.0149311308285655 1 0.010783264216221 5.00983375273955 -1.18996048484318 0.00230074933233901 51.4723206298088 14.7781428261417 3.48300332696454 0.000565047253793207 58.3528257035503 45.7234191817011 1.27621308178334 0.202808579724066 TMEM260 other 1 1 1 3.48300332696454 1.27621308178334 5.70512123508237e-17 240.649415668047 29.4971005448162 8.15840917321408 7.97416177969843e-15 -212.285911201097 56.1626876180579 -3.77983889668487 0.000187372786860481 SMG6 essential 8.03737479598405e-13 1 1.14684394715623e-10 8.15840917321408 -3.77983889668487 2.91540458147453e-15 310.516472372543 37.9283607905388 8.1869204442392 6.50140381744256e-15 -95.6257616957885 117.142795408444 -0.816317908091303 0.414927490420494 EXOC5 essential 4.02180062014412e-11 1 9.35747051444508e-11 8.1869204442392 -0.816317908091303 3.20739244206177e-07 110.311488211672 19.7641359553548 5.5813969535959 5.13836661485419e-08 128.320293888342 74.0681169838542 1.73246329343453 0.0841668111949617 CLTCL1 other 0.00344089061184387 1 0.000647074507808588 5.5813969535959 1.73246329343453 0.528320613819097 148.483370385322 229.511636885492 0.646953559306468 0.518128701156218 -174.187692502278 373.757625390059 -0.466044518343922 0.641502694815953 FSTL3 other 1 1 1 0.646953559306468 -0.466044518343922 5.30017134460308e-22 771.073042050742 82.1435325529514 9.38689898141028 1.27910666818392e-18 -847.130107839532 303.517899761297 -2.79103838193978 0.00557448722797145 DGCR2 other 7.79019184229761e-18 1 1.88655442490447e-14 9.38689898141028 -2.79103838193978 1.00884211953703e-10 101.566190098604 57.0572572414426 1.78007487581848 0.0760184894531617 -459.071648734403 92.9172274975807 -4.94065160033274 1.26101814194494e-06 RNF126 other 1.26165795469301e-06 0.018869875476064 1 1.78007487581848 -4.94065160033274 3.22268156893804e-05 129.623029906639 28.8282093854418 4.49639546367725 9.68685700369426e-06 -45.594413993089 54.84335584468 -0.831357113197364 0.406393763987975 MNT other 0.29336070322043 1 0.108889959578527 4.49639546367725 -0.831357113197364 4.70676725830473e-21 233.863224241557 22.746641806939 10.2812198049479 1.30132916767877e-21 19.743231780484 90.7694187560952 0.217509730160724 0.827949747726948 ZXDC other 6.87941102473819e-17 1 1.94496657401269e-17 10.2812198049479 0.217509730160724 1.54509647420607e-08 121.09916776853 22.7633806478856 5.31991138055228 1.95865809681219e-07 -115.661366446744 54.90004150779 -2.10676282330921 0.035918704333297 JMJD6 essential 0.000177686094533698 1 0.00240973705650804 5.31991138055228 -2.10676282330921 1.22001434171356e-14 70.3568042588177 22.8915843841465 3.07347901648708 0.00233072589797612 -274.25075636305 53.5995036711711 -5.11666596850519 5.88302766504478e-07 POLB other 1.6675156022541e-10 0.00883983736949628 1 3.07347901648708 -5.11666596850519 0.892128490285774 26.6378237535972 55.9019074314942 0.476510104529812 0.634037233871276 6.88853137015535 134.822550561651 0.0510933174121002 0.959283138707657 ST6GALNAC1 other 1 1 1 0.476510104529812 0.0510933174121002 3.39569441573193e-05 181.018106482621 39.6307292784984 4.56761986918147 7.0644014459135e-06 -5.07203453646398 92.729444811247 -0.0546971304183717 0.956414102903552 WIPI1 other 0.308295096004302 1 0.0801597632067805 4.56761986918147 -0.0546971304183717 0.056100296644465 3.52353482355222 1.47241927824423 2.39302410367366 0.0173029850312308 1.30231732774259 4.36397463921162 0.298424586623597 0.76557841301334 FRMPD1 other 1 1 1 2.39302410367366 0.298424586623597 1.11052611061586e-34 204.403277927743 17.6533156078301 11.5787471582438 5.55672200049468e-26 -319.763404549242 55.6001828672639 -5.75112145426973 2.13620331345476e-08 GBA2 other 1.68844389858035e-30 0.000324040680617953 8.38731618754666e-22 11.5787471582438 -5.75112145426973 3.95120836136359e-09 832.489299886984 185.54517810926 4.48672020674536 1.00995326251019e-05 -758.017579077193 268.629583668582 -2.82179486237222 0.00507415044347325 NDST1 other 4.67269900814858e-05 1 0.113296556988393 4.48672020674536 -2.82179486237222 9.38804381581306e-05 247.759193222181 57.2434106548203 4.32816965984395 2.02018765751423e-05 79.8723378847399 243.729527426781 0.327708910479606 0.743348773361281 ASNS other 0.811220866124406 1 0.221978219807663 4.32816965984395 0.327708910479606 1.29481323569812e-11 49.2573656355 21.5006377542153 2.29097230503512 0.0227299566734803 -241.230443181405 50.3426714770207 -4.79176881368953 2.72223480862433e-06 AP3M2 other 1.66046849345926e-07 0.0405286318307991 1 2.29097230503512 -4.79176881368953 2.39044264487444e-06 179.238227257283 49.844028818186 3.59598193619306 0.000374345445124953 -232.96228542989 131.721509762278 -1.76859713990771 0.077916758565041 CNGB1 other 0.0240191676956984 1 1 3.59598193619306 -1.76859713990771 0.103114985945486 13.4155972103395 66.8241880152166 0.200759599312822 0.841014492406595 -331.634527179126 161.164580626583 -2.05773828151188 0.040427551333893 ST6GALNAC2 other 1 1 1 0.200759599312822 -2.05773828151188 0.866026949968385 -7.58729192121371 14.8247197161274 -0.511800024992021 0.609145080487256 -9.46982355651882 37.6150287090607 -0.251756382529032 0.801391485835874 TESK2 other 1 1 1 -0.511800024992021 -0.251756382529032 1.72607246227107e-07 87.1048328821666 22.8044152183019 3.81964773261364 0.000160601798733277 -128.231583911981 60.2646309502295 -2.12780833284921 0.0341194862266598 CFAP20 other 0.00187917508967452 1 1 3.81964773261364 -2.12780833284921 4.91603777492766e-29 485.71707452468 52.1142727374075 9.32023127276672 1.98194353732562e-18 -495.655934372639 137.721023919917 -3.59898525486462 0.000370217037113994 CSNK2A2 other 7.41338496459092e-25 1 2.91979921918811e-14 9.32023127276672 -3.59898525486462 2.48504460503648e-10 87.4654431282435 13.6734187095424 6.39675014612132 5.69045667949223e-10 -24.3526897430087 40.1230583068004 -0.60694998763046 0.544318565696013 PTPN21 other 3.07350316750912e-06 1 7.6172453111683e-06 6.39675014612132 -0.60694998763046 1.89761128602202e-05 50.8327816939796 19.1376789035962 2.65616232512018 0.00829953794019086 -164.195276063456 48.5714370373498 -3.38049038856305 0.000813175550276078 EIF2B3 essential 0.176553754051489 1 1 2.65616232512018 -3.38049038856305 0.471079488069132 15.0119566731859 20.5217550306044 0.731514271113673 0.465000429361858 34.895254241247 29.7110955196779 1.17448561323279 0.241073837837053 CAMK2A other 1 1 1 0.731514271113673 1.17448561323279 2.00499423525140e-11 759.142060965098 139.410036071716 5.44539032021037 1.03154419761848e-07 -557.374176540934 201.83580263732 -2.76152282824908 0.00608548244894399 TCOF1 other 2.56057813783957e-07 1 0.0012837567539362 5.44539032021037 -2.76152282824908 9.16911993612772e-10 714.834019448284 171.082819465521 4.17829225448526 3.79328121705405e-05 -1239.25113402719 330.518520064226 -3.74941511231015 0.000210308138846692 CDC42 essential 1.11028873306571e-05 1 0.408953648010597 4.17829225448526 -3.74941511231015 4.36066325966831e-07 138.680873676486 29.0079289862372 4.78079196009764 2.67379460885254e-06 -228.483495149218 121.514990808363 -1.88029060142507 0.0609823464799064 OSBPL3 other 0.00462953892604736 1 0.0311363382200878 4.78079196009764 -1.88029060142507 3.22543620700756e-28 175.996438337501 21.1148102131591 8.33521289373546 2.38078076029737e-15 -162.310733461625 35.6414234625147 -4.55399133068667 7.51615278762822e-06 RAD18 other 4.85557166602918e-24 0.110953447450968 3.43951396440161e-11 8.33521289373546 -4.55399133068667 0.0325512746894577 254.316987548133 132.057825726342 1.92580020267139 0.0550151034245172 -460.361373617808 319.527212785956 -1.44075795486688 0.150630804357486 ATP2B1 other 1 1 1 1.92580020267139 -1.44075795486688 0.000543029579826626 177.219659586549 56.5403358341908 3.13439347276358 0.00188163908484116 -338.305238009095 179.477286845301 -1.88494735994474 0.0603429079419383 NCK2 other 1 1 1 3.13439347276358 -1.88494735994474 1.23722960709451e-08 1204.55777737093 201.754577776875 5.97041113338741 6.32146204995278e-09 -380.277429513004 641.790044575478 -0.592526220571939 0.553919357550512 MAP4K4 other 0.000142912391915487 1 8.22422212698857e-05 5.97041113338741 -0.592526220571939 0.186393542597364 -39.9291405542667 22.1285435410062 -1.80441792205051 0.0721208470260369 -45.7278225450091 70.3723299709072 -0.649798330734729 0.516296067460944 MGAT4A other 1 1 1 -1.80441792205051 -0.649798330734729 0.000641225494722117 1725.60379849412 464.63295855309 3.71390743323033 0.000240841902660073 -609.098337608935 1467.20460512273 -0.415142056862604 0.678316987720118 RPL31 essential 1 1 1 3.71390743323033 -0.415142056862604 3.14924964244793e-28 1535.79054076722 269.63381407162 5.69583806116869 2.78261940962997e-08 -2957.11980775373 505.3083376432 -5.85210966742797 1.20097807824171e-08 WDR1 essential 4.74119533670535e-24 0.000182464599427263 0.000354143972263606 5.69583806116869 -5.85210966742797 8.6307406448392e-14 165.833754755233 21.5252103172405 7.70416420147168 1.67780040166399e-13 -108.989473401607 91.5960483902826 -1.18989274446876 0.234973366526795 SNX13 other 1.16187030560825e-09 1 2.37945652963988e-09 7.70416420147168 -1.18989274446876 6.15271848432143e-10 57.8687705665466 21.2791718008697 2.7195029537842 0.00690068107788822 -172.41250049558 36.7373518501258 -4.69311182795527 4.01889819508196e-06 ARHGAP10 other 7.49928175869656e-06 0.0597007326879425 1 2.7195029537842 -4.69311182795527 0.0012894372420523 23.1003318758422 35.8567344102691 0.644239701572669 0.51988441844599 -279.418242210931 82.8476517692987 -3.37267546205186 0.000836378311416664 RPS6KA2 other 1 1 1 0.644239701572669 -3.37267546205186 0.000543369232783339 10.1791572382494 8.44844594955277 1.20485557924274 0.229154951805616 -63.3308261328717 22.0627723286605 -2.870483599679 0.00437316984768596 ING3 essential 1 1 1 1.20485557924274 -2.870483599679 0.912612185358279 0.462716463276059 24.3403367741057 0.0190102736691925 0.984844831666376 33.2895022330331 79.077069940101 0.42097541371031 0.674057406919952 VASH1 other 1 1 1 0.0190102736691925 0.42097541371031 0.0544700773193903 131.711718833147 54.9338102378146 2.39764396940523 0.017077269388758 68.8390205697457 92.3131403530709 0.745712043880822 0.456392231734499 LMCD1 other 1 1 1 2.39764396940523 0.745712043880822 4.32647665410608e-08 309.321018789388 57.9502769315826 5.33769699072499 1.79714565315575e-07 -242.80814944016 199.947167004819 -1.21436153898749 0.225513546109642 BUD23 other 0.000486339240688064 1 0.0022142631592532 5.33769699072499 -1.21436153898749 1.10231596875372e-06 379.831347988917 73.2644459111447 5.1843884610767 3.87570887357291e-07 0.857994303734935 219.889490381237 0.00390193411357393 0.996889177002342 SEL1L other 0.0113803100614134 1 0.00470859871050372 5.1843884610767 0.00390193411357393 2.45763368566631e-11 181.121151436207 25.4311499401242 7.1220197223737 7.09898103091629e-12 -108.772748235882 154.859911032538 -0.702394490030587 0.482945385649733 TRIP13 other 3.13151684227602e-07 1 9.84415699557162e-08 7.1220197223737 -0.702394490030587 1.0277492290308e-15 595.648757640993 129.545195226183 4.59799961396486 6.16425127137734e-06 -892.008425010131 213.883247566613 -4.17053899806865 3.92380386449633e-05 TCF3 other 1.42805583133718e-11 0.568088323501778 0.0702046577297165 4.59799961396486 -4.17053899806865 0.00730224144562184 211.872512068663 78.1309915717593 2.71176018384547 0.00705544046574327 -230.915375828463 238.366869080937 -0.968739392008611 0.333409131335656 TRIB2 other 1 1 1 2.71176018384547 -0.968739392008611 1.17617808286105e-06 159.734523305471 110.179187276731 1.44977038997642 0.148108063399844 -667.53187168719 181.408575088353 -3.67971509264144 0.000274154437414522 DAZAP1 other 0.0121193389658002 1 1 1.44977038997642 -3.67971509264144 2.71195374975698e-08 297.025955494459 155.986960489262 1.90417169847287 0.0577901587162532 -1038.73037691794 257.539445050333 -4.03328653874721 6.89238893613017e-05 MBD3 other 0.000308376260884866 0.989540279560209 1 1.90417169847287 -4.03328653874721 4.28590703137741e-09 298.265389348825 46.922245306542 6.35658816836797 7.17843021922683e-10 -136.126283893811 285.299973319997 -0.47713388231246 0.633595560822089 HLTF other 5.06122761335358e-05 1 9.59181845893089e-06 6.35658816836797 -0.47713388231246 0.0213469170510868 -15.1948119644604 10.5793551360256 -1.43627014776335 0.151905417820453 -84.2329315504954 32.8158980583124 -2.56683304539822 0.0107190076221869 MYO3B other 1 1 1 -1.43627014776335 -2.56683304539822 0.00708865375098575 274.098011091588 106.690400060027 2.56909722840454 0.0106535546114311 -492.13059524058 329.082460753601 -1.49546285181409 0.135788527729172 CYBRD1 other 1 1 1 2.56909722840454 -1.49546285181409 0.571801564644273 7.31642931193746 7.7505458069265 0.943988913064538 0.345889718109117 2.64715638932528 12.4869421249831 0.211993966403433 0.832247126117582 CDH19 other 1 1 1 0.943988913064538 0.211993966403433 4.79403616450659e-09 126.935128248396 30.4371804689792 4.17039707004942 3.93225890592544e-05 -259.665735959729 70.3162710741642 -3.69282574279079 0.000261210543007981 PDCD2 essential 5.65025102348746e-05 1 0.423307671222874 4.17039707004942 -3.69282574279079 5.12043208771142e-06 276.999897766249 55.2173676947531 5.01653572654046 8.73975498927728e-07 62.4445020067683 131.838835970205 0.473642698278073 0.636077691703935 SLC6A15 other 0.0501392710028703 1 0.0104466291386831 5.01653572654046 0.473642698278073 8.22422214127672e-25 547.414169862533 51.6690517531295 10.5946238858424 1.18171893372492e-22 -294.677852679468 163.623879159912 -1.80094650116121 0.0726616187215553 RDH11 other 1.22483340350034e-20 1 1.77116033786691e-18 10.5946238858424 -1.80094650116121 5.78965292668709e-09 275.421905023876 57.73178648647 4.77071509104302 2.81247578149338e-06 -406.370562444126 143.201916152689 -2.83774528555073 0.00483805094981044 PRKACA other 6.79878943180865e-05 1 0.032692218484079 4.77071509104302 -2.83774528555073 1.04267427100812e-06 366.134758522245 76.0423154259461 4.81488177301499 2.28762181184861e-06 -197.106133729643 186.841247053585 -1.05493908244529 0.292259085841414 ADGRL1 other 0.010784379985037 1 0.0267308608714511 4.81488177301499 -1.05493908244529 8.11651204073502e-22 4913.50183358949 487.998589880527 10.0686803926881 7.14332462459046e-21 -1662.35781295985 1560.59070757524 -1.06521063139145 0.287591286965419 ACTN1 other 1.19174746294112e-17 1 1.06428393581773e-16 10.0686803926881 -1.06521063139145 2.53823383446024e-15 228.9241771215 29.5699890249685 7.7417741659694 1.32764153348057e-13 -174.901122095361 93.5303449098259 -1.86999334027888 0.0624062778113156 ZFYVE26 other 3.5075853358406e-11 1 1.88538374169576e-09 7.7417741659694 -1.86999334027888 8.50526608817109e-15 334.42810377074 44.1610685917259 7.57291692514431 3.94437867638269e-13 -286.454295948848 82.1370281190362 -3.48751717110713 0.000555718763060553 EPN2 other 1.16607198068826e-10 1 5.56394056090543e-09 7.57291692514431 -3.48751717110713 0.341163487064343 -13.7465066458933 49.6515480094028 -0.276859578341647 0.782066678913383 -198.786705431479 135.51513298728 -1.4668967299035 0.143386212773556 PTPN18 other 1 1 1 -0.276859578341647 -1.4668967299035 0.70381687411375 19.8908829414707 23.7479603397526 0.837582792665127 0.402896095900809 6.11469797398704 66.7893060260706 0.0915520513358863 0.9271117745645 LIMS2 other 1 1 1 0.837582792665127 0.0915520513358863 0.000611537478306755 45.0577884676988 28.9120897491952 1.55844108324799 0.12016233294948 -165.695735226458 61.5316859237382 -2.69285219052537 0.00747474737650567 LNX1 other 1 1 1 1.55844108324799 -2.69285219052537 3.33053087303123e-05 582.91962496504 160.462885324931 3.6327380240275 0.000326516576788325 -767.168819830595 293.559289462528 -2.61333518430021 0.00938985695742072 ALDH3A2 other 0.302745256358539 1 1 3.6327380240275 -2.61333518430021 3.2127312823923e-08 2204.05528278206 365.457090149455 6.03095504832237 4.49554954056387e-09 -488.861657726542 2243.17131246663 -0.21793326930032 0.827620009301798 TFRC essential 0.000363938199669399 1 5.87388502970075e-05 6.03095504832237 -0.21793326930032 2.15686281526604e-05 151.208352854963 278.590784120358 0.542761503516345 0.587674215027743 -2428.09733441796 522.503705418681 -4.64704328263534 4.93922232290378e-06 SREBF1 other 0.19968235943733 0.0732387886040173 1 0.542761503516345 -4.64704328263534 7.4365567614503e-06 400.63585158295 116.500984234089 3.43890529523718 0.000661902988807904 -354.850089331861 174.142069911148 -2.03770455647458 0.0424068787030249 AFF4 og 0.0718148286453255 1 1 3.43890529523718 -2.03770455647458 6.35227337266673e-11 81.7722371289493 16.6667532357167 4.90630874366773 1.48863989156667e-06 -120.412734225961 38.114016392053 -3.15927697011402 0.00173457059890164 UBE2D1 other 8.00259399488555e-07 1 0.0175897689587517 4.90630874366773 -3.15927697011402 1.77550695055266e-17 221.839614981594 25.0106876987094 8.86979269238732 5.45169851928938e-17 -55.370967055583 81.4625598856127 -0.679710619618794 0.497183749805906 MPP5 other 2.51820150796883e-13 1 7.96111534771829e-13 8.86979269238732 -0.679710619618794 0.588943599976132 15.610688000142 15.168064198323 1.02918129802404 0.304181590280404 11.0125776436585 34.6867706813884 0.317486391132034 0.751084241252475 RHOBTB1 other 1 1 1 1.02918129802404 0.317486391132034 9.15052020859315e-14 400.651734353112 62.3872701021808 6.42201099193643 4.9706692661838e-10 -792.41463583797 254.146735997529 -3.11794142359426 0.0019898139187507 MARK2 other 1.23111098886412e-09 1 6.66268508439277e-06 6.42201099193643 -3.11794142359426 7.89729823373794e-06 136.863608471168 35.7662203514196 3.82661648690916 0.000156319221434821 -83.0306331377041 51.3388719363295 -1.61730536737696 0.106800754923128 HMMR other 0.0760983657802988 1 1 3.82661648690916 -1.61730536737696 0.00637829755878487 37.431353019802 31.0802296874974 1.2043460874055 0.229357118614737 -196.978828618682 75.0929810013519 -2.62313236193321 0.00913502263022278 CHFR other 1 1 1 1.2043460874055 -2.62313236193321 0.010295076085306 8.35412894952791 3.0637311100212 2.72678268735865 0.00675376520254488 -17.0911628183986 16.0951234578512 -1.06188454305155 0.289101539889959 TRHDE other 1 1 1 2.72678268735865 -1.06188454305155 3.09246211839267e-05 840.578690470605 193.658134348899 4.34052870175957 1.9090099805715e-05 43.327899952214 291.195157962049 0.148793339337946 0.881810428937218 P4HA2 other 0.282249017545699 1 0.210143818661311 4.34052870175957 0.148793339337946 0.115156401409599 -12.0663319162323 11.1168170592211 -1.08541247480758 0.278556015644248 -66.7547863378775 38.1666441565333 -1.74903473473055 0.0812437686361789 FCGR2B og 1 1 1 -1.08541247480758 -1.74903473473055 1.6810981575012e-05 183.90135613972 48.4435285859531 3.79620067958974 0.00017583978145993 -141.153660548747 129.679292236292 -1.08848265682656 0.277203743038563 NFATC3 other 0.157283543615812 1 1 3.79620067958974 -1.08848265682656 5.13724691639536e-21 71.024476713194 12.3451671966855 5.75322112545086 2.07935558478449e-08 -99.4602489551631 19.8905328862011 -5.00038131327105 9.53335606934337e-07 TRNT1 essential 7.50808636831181e-17 0.0142885940767318 0.000266032753517327 5.75322112545086 -5.00038131327105 7.76698872683882e-08 1006.9527185514 189.745230306892 5.30686709185137 2.08794600284332e-07 -823.090975832011 362.18530670466 -2.27256865641761 0.0237151246502516 ACADVL other 0.000861980408904572 1 0.00256733840509615 5.30686709185137 -2.27256865641761 0.00153939874067319 149.713290466206 51.0396700581474 2.93327308534015 0.00359620371750876 -77.0659852317116 77.3126145496448 -0.996809973128319 0.319609911048876 STK10 other 1 1 1 2.93327308534015 -0.996809973128319 2.0722632443256e-09 111.349459832296 43.2569947098965 2.57413767597733 0.010498491906212 -307.601753640217 65.3852215568339 -4.70445379423919 3.79268675685459e-06 FBXW11 other 2.47490399269806e-05 0.0563669105803728 1 2.57413767597733 -4.70445379423919 0.000148475889773068 -12.41653400647 18.7386095670222 -0.662617680466626 0.508052405744889 -151.331035014735 35.7682195345509 -4.23087973021846 3.04337861962117e-05 ACAP1 other 1 0.442294214789545 1 -0.662617680466626 -4.23087973021846 0.00601203550383899 -17.9807696281797 53.0370757013251 -0.339022643884766 0.734815732611488 240.632036741992 98.2523054311361 2.44912356698488 0.0148580832432326 CRMP1 other 1 1 1 -0.339022643884766 2.44912356698488 9.00347534601962e-07 178.574764575544 40.6464819203718 4.39336336476498 1.52242587119491e-05 -7.78226699903086 75.337744583927 -0.103298380406933 0.917791273786956 EVC other 0.00935551123204899 1 0.168684786528396 4.39336336476498 -0.103298380406933 1.91538256300145e-15 212.824009279916 24.6112825179678 8.64741644912415 2.58393783213935e-16 -22.7696596505459 46.1036428313162 -0.493879837952403 0.621729863314825 DERL2 other 2.65223023498811e-11 1 3.75885436441311e-12 8.64741644912415 -0.493879837952403 0.013208804040413 22.2502558853634 7.65637127258678 2.90610983887749 0.00391469932574545 3.29089650189659 31.4519678003761 0.10463245170489 0.916733013851234 SIDT1 other 1 1 1 2.90610983887749 0.10463245170489 0.475853696344103 -15.6826429365685 14.0173036672034 -1.11880596360778 0.264072673530053 -2.77088151034478 29.0541692033269 -0.0953694972640103 0.924081791855569 MRVI1 other 1 1 1 -1.11880596360778 -0.0953694972640103 0.127066590556928 81.4804308127641 64.2165468240104 1.26883856019332 0.205426613640014 -177.337152848231 151.410994567044 -1.17123035454144 0.242383045290703 TMEM38A other 1 1 1 1.26883856019332 -1.17123035454144 5.30935953791795e-05 120.480458661125 37.7078170670538 3.19510563146313 0.00153800856249662 -209.10504510745 92.9045864727283 -2.25075050701434 0.0250841896977086 AP1M1 other 0.472214437302423 1 1 3.19510563146313 -2.25075050701434 1.40934067128563e-33 493.643682677906 35.5023973442372 13.9045168666063 1.09594402486919e-34 235.326227335644 147.093022376718 1.59984629816738 0.110622571035021 PVR other 2.13980194121297e-29 1 1.67098585471805e-30 13.9045168666063 1.59984629816738 0.00221091539060454 106.724765923701 51.6707242353366 2.06547842135168 0.0396876803854552 -289.188718748324 128.563705699242 -2.24938070332884 0.0251721151861899 XRCC1 other 1 1 1 2.06547842135168 -2.24938070332884 0.000662630216977528 250.742563032458 66.9004749871216 3.74799376358278 0.000211452466373507 278.611042241292 171.634627237402 1.62327990992122 0.105514241105236 SCARB1 other 1 1 1 3.74799376358278 1.62327990992122 0.00144016236526183 89.7358738897672 24.866075460915 3.60876705416646 0.00035789117393635 10.9421024981517 119.523376071323 0.0915478030977152 0.927115699513673 CYP2W1 other 1 1 1 3.60876705416646 0.0915478030977152 6.74381906399254e-09 1166.57677704192 188.605265880448 6.18528211074121 1.89164652315555e-09 -99.8099028337401 758.279709956012 -0.131626761897045 0.895362234695824 MCM2 essential 7.88959392296487e-05 1 2.49867589243617e-05 6.18528211074121 -0.131626761897045 0.0203346194799679 5.24222995251915 2.1366770539258 2.45344982897036 0.01468390141316 11.9769416286694 6.11685507541644 1.95802278801807 0.0510987026982402 MOV10L1 other 1 1 1 2.45344982897036 1.95802278801807 0.0283130246908297 103.059306581377 38.4069470930659 2.68335065350674 0.00766901791248195 86.7255115499112 109.950976833783 0.788765266551632 0.430835009661198 PANX2 other 1 1 1 2.68335065350674 0.788765266551632 6.64663623284686e-08 122.167220060671 22.5975231361739 5.40622170511715 1.26345912452381e-07 -56.7649809699662 64.6919354674487 -0.877466110107788 0.380893876075573 SELENOO other 0.00073957121362887 1 0.00156656296849707 5.40622170511715 -0.877466110107788 8.72373233647505e-06 1810.68335396919 373.617699668087 4.84635325247641 1.97724444366276e-06 1673.74651057226 2382.64629603936 0.702473763459773 0.482902531766242 TP63 other 0.0837042117684781 1 0.0231752821241712 4.84635325247641 0.702473763459773 7.20033359883924e-05 12.2252322389214 22.5446999712577 0.542266353267391 0.588014821765649 -162.171126994167 41.1900401178523 -3.9371441865598 0.000101346175973201 ALPK1 other 0.630677219922329 1 1 0.542266353267391 -3.9371441865598 0.211888891480429 107.513481392171 64.7135293805205 1.66137564155995 0.0976235265469697 -53.2596292719996 159.482441315688 -0.333952934458626 0.738635191240469 LLGL2 other 1 1 1 1.66137564155995 -0.333952934458626 0.00966911401122328 46.9307740448894 23.2550892747155 2.01808616989124 0.0444164168520287 -71.6301778754908 45.5705393913791 -1.57185275469971 0.116972894870045 PDE8A other 1 1 1 2.01808616989124 -1.57185275469971 7.82609405550171e-09 99.6536059057356 19.2913100598335 5.16572516830906 4.24247472053351e-07 -142.677702063221 47.6717609416563 -2.99291864292237 0.00298036624733348 NLE1 essential 9.12913871574274e-05 1 0.00514527334106305 5.16572516830906 -2.99291864292237 4.86543166779683e-16 530.740313574615 62.4659603114919 8.49647249362744 7.73363285600512e-16 -576.670836356114 363.857416437952 -1.58488135820217 0.113990333762113 SDHA ts 6.78727717657658e-12 1 1.12129942779218e-11 8.49647249362744 -1.58488135820217 2.49882828447283e-14 446.976280239744 54.5484274732903 8.19411852813917 6.2430384383678e-15 -127.515458951973 159.043050894531 -0.801766931876414 0.423286500673008 SMARCE1 other 3.39615752142702e-10 1 8.98872674356196e-11 8.19411852813917 -0.801766931876414 0.0464262170565553 2.448084567335 1.70082289652805 1.4393530169028 0.151037236876397 -7.80516169425879 4.20299203506143 -1.85704889020678 0.0642315753463289 FNDC8 other 1 1 1 1.4393530169028 -1.85704889020678 0.487065320410292 27.3125759498797 26.9664556212252 1.01283521770589 0.311916209128163 -45.7807161567335 78.3541104061284 -0.584279700445082 0.559450344073575 GSDMB other 1 1 1 1.01283521770589 -0.584279700445082 5.04699254398072e-26 607.940202668117 53.2936645595929 11.4073634772914 2.35798369923553e-25 -401.002313685733 255.928644346021 -1.56685202123592 0.118182785292937 KDM5A other 7.55181494355835e-22 1 3.55513202333741e-21 11.4073634772914 -1.56685202123592 0.00328327597472159 9.89756874468828 3.39020908125504 2.91945673776091 0.00375591260879832 16.530272076724 8.23297634842827 2.00781240916352 0.0455061178206537 ADAM11 other 1 1 1 2.91945673776091 2.00781240916352 1.04126866949494e-09 266.786545673668 40.8476020656766 6.53126578262087 2.57303193266314e-10 -93.4797935348826 179.673763223297 -0.520275146787607 0.603232698980567 PPP2R3A other 1.2568112840804e-05 1 3.46793243884337e-06 6.53126578262087 -0.520275146787607 2.00194680437643e-06 151.205584105086 29.6689710534664 5.09642157230862 5.96980602479441e-07 203.361192734735 91.4664591315885 2.22334169995767 0.0268996876340159 FERMT2 other 0.020219662724202 1 0.00719003437626239 5.09642157230862 2.22334169995767 0.772542626635956 31.275204321644 49.0410409845819 0.637735327263478 0.524102040264778 -33.3404597219885 147.596005053422 -0.225889987401225 0.821431191580435 DHRS9 other 1 1 1 0.637735327263478 -0.225889987401225 0.269341103806939 271.632023578171 262.801510348624 1.03360145540196 0.302112887608123 -1090.34532876275 853.497540051994 -1.27750260263941 0.202362619879516 PTGS2 other 1 1 1 1.03360145540196 -1.27750260263941 1.72413619384363e-12 467.0665106019 60.7677852595117 7.68608743279469 1.91732602313573e-13 -165.392208391483 382.305269256402 -0.432618176341584 0.665586348438378 IGF2BP2 other 2.25930806841269e-08 1 2.71704270738564e-09 7.68608743279469 -0.432618176341584 6.12559378868411e-16 281.741610768469 32.4472774386078 8.6830585802319 2.07178345865474e-16 247.056937379012 204.133902277811 1.21026901765091 0.227077336913493 MAP3K13 other 8.53295214763697e-12 1 3.01589518076371e-12 8.6830585802319 1.21026901765091 0.0856107488377349 108.872211413865 51.9353555200248 2.09630241910805 0.0368428267047627 198.216594788456 322.835036848086 0.613987244766527 0.539661358824423 ST6GAL1 other 1 1 1 2.09630241910805 0.613987244766527 0.181817877429441 -4.71262589763683 2.73460973847424 -1.72332667120033 0.0857984563503752 -5.31988450674191 6.50319711713646 -0.818041405007328 0.413944157625025 TBX21 other 1 1 1 -1.72332667120033 -0.818041405007328 0.0367359028161938 57.1038495971353 22.4740374850606 2.54088076675562 0.0115368811722404 59.4377281178983 39.4030536038494 1.50845487041369 0.132440448078191 FRY other 1 1 1 2.54088076675562 1.50845487041369 3.62421561297839e-27 912.751707919927 119.645851088647 7.62877859628964 2.85312203602644e-13 -1140.5550810032 300.061567387957 -3.80107019679912 0.000173049238129776 PICALM other 5.44139732132576e-23 1 4.03288799792337e-09 7.62877859628964 -3.80107019679912 0.052639507897715 83.8235892424784 34.9163275145244 2.40069890533618 0.0169434611827688 -24.3109977549694 87.3158983582461 -0.278425787423321 0.780868204947183 NSF essential 1 1 1 2.40069890533618 -0.278425787423321 6.8485748215621e-09 245.754002528328 39.4859422241591 6.22383533697129 1.55096948785472e-09 -21.2630336172893 124.921946287383 -0.170210553463309 0.864954167879668 GLI2 other 8.00940825381688e-05 1 2.05317340802208e-05 6.22383533697129 -0.170210553463309 0.0118018153962097 167.980286354883 66.5093524385527 2.52566413889051 0.0120380983138012 -245.989547767679 207.683803026355 -1.18444261990167 0.237130816803118 CLASP1 other 1 1 1 2.52566413889051 -1.18444261990167 0.00147009064566181 160.731450730978 69.8753900060956 2.30025837017806 0.0220766007637803 -407.408331414757 197.065620994713 -2.06737395065823 0.0395025800339321 MRPS34 essential 1 1 1 2.30025837017806 -2.06737395065823 0.000156784821361669 2399.42558667482 576.052837769697 4.16528733017733 4.0104217266465e-05 393.424811251276 1459.82001279945 0.269502272747185 0.787717982139112 NOTCH3 other 1 1 0.431360960918098 4.16528733017733 0.269502272747185 9.51139623164734e-33 444.31641270882 50.3607827687376 8.82266693012242 7.82715164156047e-17 -822.807062118704 160.972615876348 -5.11147226898981 5.55597821725417e-07 CLNS1A essential 1.44268858041627e-28 0.00835007966271129 1.14198142450367e-12 8.82266693012242 -5.11147226898981 6.44820176071844e-10 756.391336435328 183.962805795261 4.11165362022768 5.00223178376548e-05 -692.959981645075 340.894721185073 -2.03276829642916 0.0429037658138402 PPP2R2C other 7.8506856436747e-06 1 0.533688109009939 4.11165362022768 -2.03276829642916 0.0002345726155681 231.003707346599 63.1354178603007 3.65886082923754 0.000296179810289873 -158.239219331524 146.972438871998 -1.07665913790367 0.282443590147929 TEAD2 other 1 1 1 3.65886082923754 -1.07665913790367 1.77012115556431e-06 14.5043295309371 3.06725973767501 4.72875816572724 3.39212340411955e-06 -2.46902989154258 4.6704666584339 -0.528647364837521 0.597416554216144 CDHR2 other 0.0179490285174221 1 0.0392502599090673 4.72875816572724 -0.528647364837521 0.000544469733296529 15.4879614316657 4.18970477207693 3.69667131080169 0.00025693544410251 15.9688279682477 6.3795955087583 2.50310978906496 0.0128087387799406 SNCB other 1 1 1 3.69667131080169 2.50310978906496 1.70633056695478e-26 259.512229788516 39.7738331494127 6.52469750183856 2.67448002306852e-10 -504.124672065319 83.215756356579 -6.05804350206405 3.87806109368488e-09 TSG101 essential 2.55659508846835e-22 5.90667485179143e-05 3.60305948707791e-06 6.52469750183856 -6.05804350206405 5.46462861741739e-16 244.03849028298 28.262188417434 8.63480515657593 2.82587894742893e-16 -86.7519221637413 53.5622292351259 -1.61964734109405 0.106293100978835 NCBP3 other 7.61878521840333e-12 1 4.10854540166692e-12 8.63480515657593 -1.61964734109405 0.0255474221628231 -27.6815777038409 79.3310472672866 -0.348937505017103 0.727365710413449 -408.094528929764 150.347442187876 -2.71434301103576 0.00700077309285152 ATP2A3 other 1 1 1 -0.348937505017103 -2.71434301103576 0.000170796360385745 1601.9098582483 477.517223667887 3.35466403901365 0.000890137461766193 -1128.52727144975 934.419928957136 -1.20773031104896 0.228042863309425 CA12 other 1 1 1 3.35466403901365 -1.20773031104896 0.00110405303578975 371.407677262885 101.492156712469 3.65947171972211 0.00029550317696035 -13.957735670463 408.045039439801 -0.0342063603802791 0.97273392119396 MGLL other 1 1 1 3.65947171972211 -0.0342063603802791 0.571610300537465 -17.6042653325557 33.9501684371172 -0.518532488731609 0.604445163325497 67.8643262725249 82.6256798119602 0.821346661558136 0.412060324870157 NTN4 other 1 1 1 -0.518532488731609 0.821346661558136 1.14968215053625e-10 49.4667783128898 18.440968739087 2.68243924778428 0.00768947433635027 -146.616914740226 32.3725627723558 -4.52904874325946 8.38155632534688e-06 BCS1L essential 1.43376860993375e-06 0.123569284904589 1 2.68243924778428 -4.52904874325946 0.0712367488525651 144.648797947436 63.1041376441743 2.29222366943777 0.022541543894398 103.673062903055 172.210890283871 0.602012234720819 0.547592293348346 NUAK1 other 1 1 1 2.29222366943777 0.602012234720819 0.00182042943880543 75.0944758740846 31.9638848945518 2.34935384487273 0.0194135885457829 -106.16051248757 62.5969217370749 -1.69593822733767 0.090870163976789 DPP8 other 1 1 1 2.34935384487273 -1.69593822733767 0.00205192773834879 23.1275840697236 10.5664152123512 2.18878243992243 0.0293349961330971 -37.9615226423711 20.6928872466853 -1.83452034459097 0.0675050622695785 SLC24A1 other 1 1 1 2.18878243992243 -1.83452034459097 1.03954730316626e-11 362.83692900339 90.4860863160802 4.00986432031054 7.56624959893429e-05 -336.437231796657 137.065287040661 -2.45457649460764 0.0146371587772254 ZNF532 other 1.33623410348991e-07 1 0.794153557904143 4.00986432031054 -2.45457649460764 0.997825749397931 0.517684931869488 7.8707516921578 0.065773251668617 0.947599552703894 0.120236934696226 15.0087532486087 0.00801112075763999 0.993613126357429 SCARF1 other 1 1 1 0.065773251668617 0.00801112075763999 3.36013092081363e-13 623.628290984332 199.328489848394 3.12864604281432 0.00191770238114113 -1158.76962075143 301.936107403469 -3.83779744236748 0.000149588011544162 LMAN1 other 4.46729405922172e-09 1 1 3.12864604281432 -3.83779744236748 0.015133767378874 105.540640545256 101.85921088397 1.036142334398 0.300918089014787 -434.008336628632 199.477412490335 -2.17572672118784 0.0303071124823679 HACD3 other 1 1 1 1.036142334398 -2.17572672118784 0.163852347043766 -16.4387702313207 8.98569154091413 -1.82943851972559 0.068267208865815 2.33335332004913 19.6485674897534 0.118754373379431 0.905544703233226 IPCEF1 other 1 1 1 -1.82943851972559 0.118754373379431 6.64714346802897e-08 207.095022630317 42.0959598316784 4.91959379138499 1.3898723944975e-06 -243.268576509274 79.827900867789 -3.04741292035444 0.0025004509701713 ZZEF1 other 0.00073957121362887 1 0.0164533094060614 4.91959379138499 -3.04741292035444 4.62910693342335e-09 6333.33113694222 1823.92165382227 3.47237016659674 0.000586820685267601 -16960.2516088131 4115.16657140904 -4.1214009966566 4.80192794251675e-05 ENO1 essential 5.4595687172795e-05 0.693158298502293 1 3.47237016659674 -4.1214009966566 0.00304747493743291 229.880321157964 116.970641964945 1.96528220497292 0.0502489353639958 -351.653162350158 218.790684581845 -1.60725838498216 0.108987002587016 MYDGF other 1 1 1 1.96528220497292 -1.60725838498216 7.53024091238634e-07 53.8489715032307 16.1132525946808 3.34190575036396 0.000931252656671974 -116.95387018003 37.5903996967113 -3.11126966256392 0.00203172877502785 ANO8 other 0.00786232453662258 1 1 3.34190575036396 -3.11126966256392 0.0165219973973 4.63176993712276 8.4559069074818 0.547755549794968 0.584242816504672 -50.6749415918708 19.3651454069545 -2.6168118300662 0.00929811589057851 TUBE1 essential 1 1 1 0.547755549794968 -2.6168118300662 0.000286446563724358 105.344942871327 52.1548146537313 2.01985077639981 0.0442319376255249 -275.951278044527 100.888706523183 -2.73520483663965 0.00658173553127603 ARHGEF10L other 1 1 1 2.01985077639981 -2.73520483663965 0.623829771310513 -16.254457630402 18.7586105843274 -0.866506480175156 0.386861706906209 15.4261406227628 50.4724321100111 0.305634976914518 0.760081310116909 WSCD2 other 1 1 1 -0.866506480175156 0.305634976914518 0.0340994021744634 -4.01474528535037 3.00896329409552 -1.33426196764464 0.183069688960434 -16.2183171712673 6.26080143327827 -2.59045384909694 0.0100249214931906 TACR2 other 1 1 1 -1.33426196764464 -2.59045384909694 0.0606959372791257 43.7715169310247 21.8222812199442 2.00581765443571 0.0457171350300292 -54.527253097631 55.0782658549218 -0.989995822331404 0.322924136256799 ACTR6 essential 1 1 1 2.00581765443571 -0.989995822331404 0.00881623587412014 -4.17124547795795 12.872339263259 -0.324047198620982 0.746113999010274 -75.5253627074097 25.2280484606981 -2.99370610553044 0.00297082671875152 TIPIN other 1 1 1 -0.324047198620982 -2.99370610553044 5.31330762303101e-10 189.977437241714 33.1157441083131 5.73677090330045 2.27635487313334e-08 -257.00776373941 127.910061322003 -2.00928497010422 0.0453651001159488 SRI other 6.4955185691554e-06 1 0.000290576699555471 5.73677090330045 -2.00928497010422 9.03533041362028e-06 319.521654384951 74.2879398948624 4.30112417758738 2.26178636257663e-05 -153.316104348482 144.728462570744 -1.05933623300628 0.290248125138377 EIF4G3 other 0.086612677344964 1 0.247597753111264 4.30112417758738 -1.05933623300628 0.0227249354229105 64.6708969676692 28.2514019199072 2.28912169212032 0.0227274328763641 -91.5908148072222 73.4012214275718 -1.24781049996012 0.213018513199376 NUP37 other 1 1 1 2.28912169212032 -1.24781049996012 0.694752540093428 12.8042901978503 29.8487173326073 0.428972878638998 0.66823525703893 -65.8005714629356 110.027136378676 -0.598039480337582 0.550241954819516 SEMA3A other 1 1 1 0.428972878638998 -0.598039480337582 0.11550407570608 28.6326003997818 23.7594220389034 1.20510508853705 0.229058763820485 -81.0041963125009 60.2003546302147 -1.34557672973981 0.179397680771819 GTSE1 other 1 1 1 1.20510508853705 -1.34557672973981 0.00513653130839767 486.0182773048 176.169435007702 2.75881157979278 0.00613819428932871 -647.439797267093 647.486297909567 -0.999928182816187 0.318107921962856 SEMA3C other 1 1 1 2.75881157979278 -0.999928182816187 0.00308964103989573 45.9592222424131 17.7519204429677 2.58897184617677 0.0100686565576874 -68.9145864493492 44.9788679322325 -1.53215475661103 0.126478454451495 TTC38 other 1 1 1 2.58897184617677 -1.53215475661103 0.000989279238249992 127.055752019377 52.2722412426361 2.43065437790609 0.0156276851537889 -64.5817039930921 96.1907326957378 -0.671392162043004 0.502461227647359 ACAT1 other 1 1 1 2.43065437790609 -0.671392162043004 0.0109946071631801 96.5515392409096 62.6057711553988 1.5422146785997 0.124015933672149 -331.960909622203 156.068487447434 -2.12702073975064 0.0341878163013337 GRAMD4 other 1 1 1 1.5422146785997 -2.12702073975064 6.16647900636412e-08 1044.42614994468 223.720595156425 4.66843988687952 4.4815116034117e-06 -1316.79035790222 564.254852498346 -2.33368016610204 0.0202352729930459 CELSR1 other 0.000687685738789726 1 0.0514387901839595 4.66843988687952 -2.33368016610204 0.0429226817081417 129.594800962739 51.3967439111663 2.52145935911291 0.0121722116168761 41.457279240713 214.113195073913 0.193623187148283 0.846593785506964 ZNF638 other 1 1 1 2.52145935911291 0.193623187148283 0.0188254452048388 25.5950222368319 15.6807280949857 1.63225980845982 0.103630366395974 -110.778001484777 60.5670488829443 -1.82901434902126 0.0683487994299906 SLC25A40 other 1 1 1 1.63225980845982 -1.82901434902126 2.08076624225963e-21 106.649197818169 24.0483824473337 4.43477635353362 1.27373336787559e-05 -169.655715590207 36.479002130448 -4.65077731522158 4.86755361876361e-06 TIMM21 other 3.04769831503768e-17 0.0721906877198831 0.141868422513983 4.43477635353362 -4.65077731522158 0.67263522783905 17.2869245808402 34.0326597750089 0.507951029837944 0.611837630126897 -98.8183837905091 141.303203856674 -0.699335762342248 0.484850233657416 ADD2 other 1 1 1 0.507951029837944 -0.699335762342248 0.00199305156780108 144.222907757882 46.1820382297774 3.12292209885379 0.00195425115083749 -255.657156531524 142.802607873186 -1.79028352730475 0.0743536001254056 RASAL2 other 1 1 1 3.12292209885379 -1.79028352730475 2.23853151177029e-05 -3.75839235862776 21.4485939605593 -0.175227913099519 0.861011721467319 -235.129015799972 54.768220304971 -4.29316516933873 2.33982235726224e-05 VPS9D1 other 0.207041779523634 0.341005710347399 1 -0.175227913099519 -4.29316516933873 0.00167540861474812 22.4805200271339 22.0150272128429 1.02114432154867 0.308034232664031 -114.499147448364 45.0181516403093 -2.54339956831637 0.011495495749598 ZNF37A other 1 1 1 1.02114432154867 -2.54339956831637 1.4890136472692e-29 617.804704079231 56.7027341941065 10.8955011228267 1.08301708849961e-23 -536.33125175894 166.990931661536 -3.21173878379215 0.00145477574272029 MARK3 other 2.24796390328231e-25 1 1.62669166692642e-19 10.8955011228267 -3.21173878379215 0.107320370808958 468.457522164278 258.904038737681 1.80938669187356 0.0713291805996369 -514.332119532188 635.198080709781 -0.809719259474879 0.418703234537448 SLC25A3 essential 1 1 1 1.80938669187356 -0.809719259474879 5.57129115092080e-09 405.994529628043 63.8750365929054 6.35607510044287 7.25253835333475e-10 -73.2178027182383 461.188522554924 -0.158758943766903 0.873960531279887 FNDC3B other 6.54682423144703e-05 1 9.69011649389057e-06 6.35607510044287 -0.158758943766903 5.51026626930337e-07 1478.03021534801 269.318243996398 5.48804341442154 8.27881097816655e-08 459.560947055326 955.152751617494 0.481138693551463 0.630746748650141 FOSL2 other 0.00580892270109961 1 0.001034023491173 5.48804341442154 0.481138693551463 0.0304149088874907 41.6994951590152 15.9213304433527 2.61909614321365 0.00923874541041163 -4.95985160209736 37.4799801665542 -0.132333357169793 0.894804316506908 CACNG4 other 1 1 1 2.61909614321365 -0.132333357169793 2.25326850563341e-11 216.917022981302 63.2866674855936 3.42753113095551 0.000695420737316423 -562.298659754558 136.9998810258 -4.10437334357002 5.24776297815525e-05 FRYL other 2.87314267153316e-07 0.756569988560642 1 3.42753113095551 -4.10437334357002 0.00122123685954216 172.109972645711 53.5232712837286 3.21561011720211 0.00143903150814224 -228.471956718606 175.938272488357 -1.29859156559427 0.19504929369266 TMEM131 other 1 1 1 3.21561011720211 -1.29859156559427 8.95318095845644e-22 5038.22936405874 491.406047204856 10.2526808384155 1.65641215890027e-21 -2929.70839864372 2358.14474833212 -1.24237852689741 0.215009455512028 FSCN1 other 1.31450602832057e-17 1 2.47451412418111e-17 10.2526808384155 -1.24237852689741 2.85390600194472e-10 13795.5099693329 2316.37880157365 5.95563642697853 6.83769766812019e-09 -27306.7331489571 11115.7698142889 -2.45657598215603 0.0145591656664443 ACTB essential 3.52286156880056e-06 1 8.88763942902262e-05 5.95563642697853 -2.45657598215603 1.79014297833985e-05 91.3890680988587 46.3844993806187 1.97025017665804 0.0496880669585917 -207.54039171302 82.9990902371246 -2.50051405527563 0.0129107549119814 MOCOS other 0.167020339879108 1 1 1.97025017665804 -2.50051405527563 4.92593521123373e-14 336.624870433947 40.9468653910833 8.22101685242191 5.28437016076753e-15 -125.669438656449 295.795133438214 -0.424852962236781 0.671233002391212 PLD1 other 6.65296809629228e-10 1 7.61213521658563e-11 8.22101685242191 -0.424852962236781 0.174423407531198 126.271355381423 80.1618652908286 1.5752048049694 0.116197269052957 234.729406780413 148.954363933649 1.57584780050467 0.116048952458813 ATP12A other 1 1 1 1.5752048049694 1.57584780050467 2.9507461036282e-05 48.4772261451469 18.3698577089515 2.63895490717516 0.00872573298115715 -275.587851375912 85.0113347849744 -3.24177772379386 0.00131382123253329 WDR62 other 0.269845731176799 1 1 2.63895490717516 -3.24177772379386 5.20915647069419e-17 475.62385955949 51.7849657988413 9.18459348620699 5.53471267682996e-18 183.126722907709 327.962472582981 0.558377065111845 0.576981100258389 DLG1 other 7.34126421414932e-13 1 8.12938597972784e-14 9.18459348620699 0.558377065111845 7.15880994680665e-25 1965.92331076601 180.031922355808 10.9198595729075 8.31346013149678e-24 -1151.06598380496 722.376510466176 -1.59344326279675 0.112048011655031 RAB7A other 1.06644791777579e-20 1 1.24901425015608e-19 10.9198595729075 -1.59344326279675 3.12313812944041e-19 251.934315724267 26.7475862930786 9.41895515220601 9.93729423262984e-19 -110.940772314881 119.226692627812 -0.930502808303196 0.352821113776064 BCAP29 other 4.50325286884013e-15 1 1.46644650990919e-14 9.41895515220601 -0.930502808303196 0.165130514454815 -19.4901538217151 13.6310619948222 -1.42983384780427 0.153740299455677 -44.1437849143524 24.9660968916989 -1.7681492267632 0.0779887489354796 SEC31B other 1 1 1 -1.42983384780427 -1.7681492267632 0.000724860183902803 159.819537514041 45.5382921926574 3.50956370603223 0.000513196393731641 -132.408567997831 127.711328775017 -1.0367801295928 0.300621145322206 SART3 essential 1 1 1 3.50956370603223 -1.0367801295928 0.0101824447653276 -21.9448094845247 7.24044694907468 -3.03086392854922 0.00264141719478051 -3.23965642017843 18.5795610175717 -0.174366682674285 0.861689664371596 ARHGAP15 other 1 1 1 -3.03086392854922 -0.174366682674285 4.67151187916085e-11 207.395225889138 46.2455337929926 4.48465416828131 1.01920160468729e-05 -160.045872049556 66.2712361063999 -2.41501262768962 0.0162949531838375 EXOSC7 essential 5.90759392238681e-07 1 0.114283075933586 4.48465416828131 -2.41501262768962 0.00387773427673439 79.6064518834096 31.3699871827126 2.53766287565713 0.0116337070349419 -230.394167017589 101.148680394756 -2.2777772890207 0.0233990476212975 KIFAP3 other 1 1 1 2.53766287565713 -2.2777772890207 1.68830980604174e-34 170.724448065873 20.8057529880866 8.20563659309181 5.71719242151606e-15 -211.838842096234 33.4871824565931 -6.32596792431925 8.50252043637705e-10 MKRN2 other 2.56639973616405e-30 1.29816482022605e-05 8.23332880622528e-11 8.20563659309181 -6.32596792431925 0.0408813920693696 -33.5718916702913 103.781914948072 -0.323484989529142 0.746543308877929 -679.430498076719 267.574197327787 -2.53922278329548 0.0115921184704352 MCM6 essential 1 1 1 -0.323484989529142 -2.53922278329548 1.98689715786244e-27 251.611580279537 50.1326691098017 5.01891450719393 8.64005439117911e-07 -487.196010697571 91.7637028931069 -5.30924532617317 2.0630674683298e-07 REXO2 other 2.98531297968831e-23 0.00311213727597551 0.010331777040972 5.01891450719393 -5.30924532617317 2.74843402923418e-25 117.239436745837 19.8400812629399 5.90922160005633 8.79645550445746e-09 -140.561873189212 36.3156272090759 -3.8705616284684 0.000131625468794015 RBM7 other 4.10231263203494e-21 1 0.000113817337772175 5.90922160005633 -3.8705616284684 0.000428382035943067 147.012241594442 41.771880427551 3.51940683755953 0.000495212650536101 -138.594488151042 119.345954063534 -1.16128350758552 0.246392128247287 RBMS2 other 1 1 1 3.51940683755953 -1.16128350758552 9.96319934631647e-07 456.000708191414 113.913759333329 4.00303449609704 7.77732033306716e-05 -894.190531191736 325.461677794933 -2.74745259488015 0.00634641273937355 BAZ2A other 0.01031888556298 1 0.81529649051543 4.00303449609704 -2.74745259488015 3.53446709526189e-20 305.012107557399 61.7629850609271 4.93842885437798 1.27260450448319e-06 -439.220248490074 89.1573798030868 -4.92634765019045 1.3478889553365e-06 PTPN23 essential 5.13487379599647e-16 0.0201617229939234 0.0150981798411885 4.93842885437798 -4.92634765019045 4.99947022907651e-29 96.2133718489502 30.2761092535794 3.17786446875024 0.00162848662992568 -377.285314755212 43.3687024327315 -8.69948358128567 1.78418349087851e-16 MLH1 ts 7.53820121140156e-25 2.74014900529121e-12 1 3.17786446875024 -8.69948358128567 0.244431708338839 88.3580276561958 70.3873348425622 1.25531145416756 0.210281622272251 -182.022552968975 197.400025974736 -0.922099944365108 0.357171132880955 UNG other 1 1 1 1.25531145416756 -0.922099944365108 0.82971580857946 5.55174796236644 9.35631967646292 0.593368776863472 0.553353534386652 -4.94204115190331 30.1683065126418 -0.163815663628066 0.869979675958353 FMO4 other 1 1 1 0.593368776863472 -0.163815663628066 0.0012915827046432 53.2926984723477 14.5430928542365 3.66446800598013 0.000290302720006085 -23.3509069574237 46.819301816891 -0.49874530484774 0.618303633735006 KLHL20 other 1 1 1 3.66446800598013 -0.49874530484774 5.20648200832805e-06 26.0555418171027 5.23186204874712 4.98016606216562 1.04879287026051e-06 30.8473834698458 14.1142645512718 2.18554664026516 0.0295849215502847 RGS11 other 0.0509402199694816 1 0.0124921718776729 4.98016606216562 2.18554664026516 1.55173838590393e-06 110.5646604619 21.6125655209918 5.11575825435952 5.48709741247344e-07 -45.8505612838409 69.2161701460312 -0.66242557464688 0.508190689650322 SLC46A1 other 0.0158308350129919 1 0.00662292657685544 5.11575825435952 -0.66242557464688 0.000204011777098563 371.160785619175 90.2835064506148 4.11105859985845 5.01082931875567e-05 245.964047936084 305.992993637447 0.803822483032118 0.422096211423239 PLXNA2 other 1 1 0.534505163431667 4.11105859985845 0.803822483032118 1.6229742045431e-17 416.307487621948 47.5601947752902 8.75327549832154 1.33005089129764e-16 -334.761070124968 152.33613356579 -2.1975158636962 0.0287182878474485 SPAG5 other 2.30283809882621e-13 1 1.93815015879892e-12 8.75327549832154 -2.1975158636962 9.29229860896257e-05 136.002230327812 47.377546858535 2.87060515678243 0.00436978778784324 -377.54719311696 132.867671524456 -2.84152788097492 0.00477782341523179 ANKRD13A other 0.803690906689173 1 1 2.87060515678243 -2.84152788097492 0.533177314101093 20.2508971664296 77.2710091057842 0.2620762612108 0.793432864856185 -394.315010317654 371.109529941607 -1.06253000395786 0.288803911134099 TPD52 other 1 1 1 0.2620762612108 -1.06253000395786 0.115230199520941 -20.1448967734438 30.4938764602798 -0.660621052875444 0.509330644078019 158.99320215362 85.5195330068061 1.85914488261958 0.0639243588921923 ACACB other 1 1 1 -0.660621052875444 1.85914488261958 2.41613786880183e-10 390.997710942797 62.1153179719112 6.29470674398879 1.03926681931839e-09 -391.279297562452 197.38062050569 -1.98235924357717 0.0483132320527807 TRAF4 other 2.98948738506851e-06 1 1.38274450310312e-05 6.29470674398879 -1.98235924357717 0.00526341710470266 52.6876966309074 20.8081915627367 2.53206514713468 0.0118218515051329 -181.709275115508 99.9794334747298 -1.81746654087048 0.0700896769356329 PAG1 other 1 1 1 2.53206514713468 -1.81746654087048 1.27796064589749e-07 33.1854523594831 8.82856656974167 3.75887207706178 0.000202948591699664 -88.2520664262095 26.7173025082153 -3.30318026676057 0.00106454738461325 GPATCH1 other 0.00140153944035577 1 1 3.75887207706178 -3.30318026676057 0.1228882869125 -12.522712951416 29.1743749084525 -0.42923671854878 0.668039806916083 -126.86198914537 62.2641732131877 -2.03747970299075 0.0424243424536674 ICAM3 other 1 1 1 -0.42923671854878 -2.03747970299075 0.00131332053821952 113.446750348367 97.9396989101186 1.15833264356346 0.247592054902554 -477.219070677214 180.234590473554 -2.64776627740188 0.00850386434866348 NT5C2 other 1 1 1 1.15833264356346 -2.64776627740188 0.000411798026154319 174.326914023905 74.7182894365933 2.33312238995836 0.0202610117273379 -262.078902262922 138.731754147771 -1.88910537369668 0.0597817020657762 CAMSAP3 other 1 1 1 2.33312238995836 -1.88910537369668 0.366214016056193 47.676534975875 34.5289656530816 1.38076927802846 0.168316524296852 48.1626777694323 67.1421331719208 0.717324211998289 0.473698990090941 RAP1GAP other 1 1 1 1.38076927802846 0.717324211998289 2.6442832335283e-12 302.25790332808 68.3296214314791 4.42352667841405 1.33268405193063e-05 -459.827181164277 126.869717078931 -3.62440456045315 0.000336793496847777 XAB2 essential 3.4486741931676e-08 1 0.148274427617802 4.42352667841405 -3.62440456045315 1.49589015547396e-09 157.566223020808 76.9468219240493 2.0477287960812 0.0414025894081383 -674.186468517704 142.869539200017 -4.71889580027165 3.54949201179529e-06 STXBP2 other 1.7949185975532e-05 0.0527738472313723 1 2.0477287960812 -4.71889580027165 2.87211006331693e-20 166.123402400781 31.0587266279568 5.34868684060115 1.69334335237631e-07 -326.329754426852 57.8085515153858 -5.64500832268733 3.6520652339903e-08 MAP2K7 other 4.17547361005015e-16 0.00055328788294953 0.00208840035648571 5.34868684060115 -5.64500832268733 0.422985464035563 9.35756429652037 18.0417128389903 0.51866274449827 0.604356668216048 43.1714321734744 32.9587949928378 1.30986075743534 0.191188400240401 NMRK2 other 1 1 1 0.51866274449827 1.30986075743534 0.0491814381755038 72.2064848693408 29.2994434763543 2.46443195849826 0.0142481830269583 52.3458821711741 50.5374837063751 1.0357833103703 0.301085329192198 DGKD other 1 1 1 2.46443195849826 1.0357833103703 0.315655837403963 -15.465430466864 13.0464468825883 -1.18541320913237 0.236747589799235 -45.4741062064428 33.3620975950293 -1.3630469749965 0.173841222851489 CTTNBP2 other 1 1 1 -1.18541320913237 -1.3630469749965 0.129712321252778 -39.7469474136906 33.8024876571224 -1.1758586473536 0.240525427683548 -101.069745830413 50.0710848194855 -2.01852518663789 0.0443704593868609 RARB og 1 1 1 -1.1758586473536 -2.01852518663789 2.11362918011503e-09 554.773336762444 160.193361104591 3.46314811635814 0.000606546294905219 -969.478969074052 293.391120928614 -3.30439096454435 0.00105976392380036 TM9SF3 other 2.52388460397535e-05 1 1 3.46314811635814 -3.30439096454435 0.00395764834630809 -175.808823209489 175.705105088426 -1.00059029657113 0.317780936302908 -1070.46827603961 322.807881392538 -3.31611567667366 0.00101771091880182 NFKB2 other 1 1 1 -1.00059029657113 -3.31611567667366 0.0260294030697038 72.4731520928464 28.0613187451606 2.58267092687313 0.0102490436506467 87.0815116058171 95.3694110115335 0.913096879619881 0.36188116538095 UBE2T other 1 1 1 2.58267092687313 0.913096879619881 0.487114924062807 73.716594577385 93.292120399472 0.790169569109742 0.430015734772298 -279.738177826874 317.063308938362 -0.882278617363624 0.378290491822746 PPP1R12B other 1 1 1 0.790169569109742 -0.882278617363624 3.65640598359909e-13 485.32515655844 65.6643810873572 7.39099567408979 1.3054882799905e-12 -399.493490912802 229.892328511678 -1.73774172239292 0.0832274738537071 DNAJC10 other 4.85936355220319e-09 1 1.83016401971868e-08 7.39099567408979 -1.73774172239292 2.43115149314704e-09 476.174033791111 96.4537206965121 4.93681353453822 1.28242985883174e-06 -858.312404313197 336.107065441531 -2.55368747808281 0.0111236025173896 GTF3C1 essential 2.89939127072716e-05 1 0.0152109005556033 4.93681353453822 -2.55368747808281 0.00107106352495654 69.0834935707586 143.986112761296 0.479792753939312 0.631703560050133 -1702.58395833523 501.740622083463 -3.39335481999704 0.000777479947581604 IL4R other 1 1 1 0.479792753939312 -3.39335481999704 0.00415212327188669 40.6993356558829 37.2237478853247 1.09337017275277 0.275053688463643 -210.243642442314 79.2342260806211 -2.6534447655031 0.00836518429981379 USP33 other 1 1 1 1.09337017275277 -2.6534447655031 0.31414666662126 21.8819751272709 56.2707356616173 0.388869540623347 0.69763127570199 -215.582407886472 164.336290623489 -1.31183688684074 0.190515501752463 SNRPA other 1 1 1 0.388869540623347 -1.31183688684074 0.27867847482298 -22.7083832811199 17.532257471813 -1.29523441676742 0.19617301330559 -51.6701867831116 34.8876634997946 -1.48104463296649 0.13957862205617 SPAG6 other 1 1 1 -1.29523441676742 -1.48104463296649 3.77177232695999e-07 101.637257771032 27.8035541980433 3.65554910883245 0.000300015959078021 -220.322726129285 72.6000139479826 -3.03474771075313 0.00260538828902689 EXOSC5 essential 0.0040252354273317 1 1 3.65554910883245 -3.03474771075313 2.68077287687888e-14 284.725684274686 35.5614163027609 8.00659011583238 2.27757149091969e-14 -123.928209691605 108.680431783395 -1.14029920251512 0.255025191121762 DYNC1I2 essential 3.64102572137689e-10 1 3.26284891789155e-10 8.00659011583238 -1.14029920251512 0.0263511381732944 -35.6869587671139 16.050248503526 -2.22345210164652 0.0268854997983523 -78.9865158621274 32.37066402187 -2.44006473913427 0.0152287411863753 APBB1IP other 1 1 1 -2.22345210164652 -2.44006473913427 1.95114859816469e-11 170.976132581506 24.5716526379975 6.95826752479439 1.95323148452905e-11 -67.1431190596463 105.369435418761 -0.637216274271613 0.52443959916828 LRCH4 other 2.49220210443576e-07 1 2.68745119956351e-07 6.95826752479439 -0.637216274271613 3.48624669561763e-08 35.0473855317424 12.7048336825409 2.75858672435082 0.0061455815285073 -79.7634212626951 29.6365241938361 -2.69138920411202 0.00749674811954155 FAM76B other 0.000394050464005661 1 1 2.75858672435082 -2.69138920411202 6.05634780475768e-09 53.4880951104943 23.3370686304582 2.29198002360437 0.0225557755109777 -180.020493747102 43.2158464573185 -4.16561304485606 3.99884697657503e-05 SIRT6 other 7.10288470541981e-05 0.57879311138947 1 2.29198002360437 -4.16561304485606 3.63818758614404e-12 88.0571292265491 18.8163312944328 4.67982455499191 4.26505479543397e-06 -213.169915273412 65.2809435275776 -3.26542331887957 0.00121295990071339 POLD3 essential 4.73219059329755e-08 1 0.0490353349831044 4.67982455499191 -3.26542331887957 0.612914735068115 494.536436478252 504.198765156354 0.980836270641985 0.327414449111054 157.408699944936 1619.17097813176 0.0972156134657 0.922616028419419 ACTN2 other 1 1 1 0.980836270641985 0.0972156134657 4.55854358215692e-14 769.274027192884 146.434614496242 5.25336191746266 2.73123572252304e-07 -1248.41775828904 283.955946653732 -4.39651915376654 1.49891282868267e-05 CAPZB other 6.16041579692686e-10 0.21969565330002 0.00334194003007919 5.25336191746266 -4.39651915376654 0.101862745795568 45.3553821005738 21.2832619419669 2.13103528135134 0.0338481738672776 10.9324978380462 68.3485213330945 0.159952221713284 0.873019627729273 GPR137B other 1 1 1 2.13103528135134 0.159952221713284 1.37986610715055e-05 9.23354455717472 2.11444147519694 4.36689530804568 1.70716486271268e-05 4.4672305885493 5.20177672669194 0.858789375873545 0.391103595962583 NAALAD2 other 0.130135172565369 1 0.188539287437988 4.36689530804568 0.858789375873545 0.0686983508565865 18.7188285617222 29.4901069929012 0.634749428553385 0.526048257335757 -98.6806994208546 53.0280981946827 -1.86091341723339 0.0636791457034787 JADE1 other 1 1 1 0.634749428553385 -1.86091341723339 0.0843348888796594 152.735515033271 118.774804468522 1.28592520709011 0.199516615199145 -239.13693291806 281.522248411182 -0.849442394935639 0.396350646412555 FGFR1 og 1 1 1 1.28592520709011 -0.849442394935639 0.00644353033961402 -67.4408019702582 21.3133506383217 -3.16425151139769 0.00170463656714913 -65.8376762664892 53.2169628761113 -1.23715583731749 0.216939163948747 SMC1B other 1 1 1 -3.16425151139769 -1.23715583731749 0.272337557831435 724.765923486375 577.633971100741 1.25471485360402 0.210500780780677 -989.124022273744 1442.28498454758 -0.685803452764931 0.493335160464136 FBLN1 other 1 1 1 1.25471485360402 -0.685803452764931 0.186805502084675 -10.7593239370643 8.94428912717494 -1.20292667020064 0.229896734954836 -32.2789821627032 17.8561320236553 -1.8077253304322 0.0715910655571048 ITGA8 other 1 1 1 -1.20292667020064 -1.8077253304322 0.122881925172686 -19.5201498136787 10.0870253213554 -1.93517406686313 0.0538666862503545 -52.6226700378948 43.9774988022123 -1.19658169452892 0.232372324469478 CST7 other 1 1 1 -1.93517406686313 -1.19658169452892 0.00533016869700909 232.874101173072 72.7686300631784 3.20019905515451 0.00151237460445808 112.27342960533 135.860662583218 0.826386589543968 0.409206379297655 MAP2 other 1 1 1 3.20019905515451 0.826386589543968 1.7856404169493e-17 192.186180934824 28.8772215236128 6.65528644359616 1.26008123297404e-10 -65.6634650173149 46.6053771954246 -1.40892465566744 0.159846936675226 PIAS2 other 2.5323952393175e-13 1 1.70930019252929e-06 6.65528644359616 -1.40892465566744 0.198296219718958 5.68991492975976 3.85864909050648 1.47458729630502 0.141306657115981 -12.2652344487287 16.0936855476064 -0.762114707190419 0.446552896448682 AMPH other 1 1 1 1.47458729630502 -0.762114707190419 3.92323535392769e-17 212.010296738631 24.1266943666197 8.7873744126322 1.03109945374695e-16 361.694969376819 156.714102139862 2.30799248081719 0.0216513123259987 MCCC1 other 5.53764670206894e-13 1 1.50334300356305e-12 8.7873744126322 2.30799248081719 0.00217273509613304 195.739432246211 56.4675443779455 3.46640595766125 0.000601185761474277 176.049434236718 366.782965903356 0.479982579897414 0.631575025511278 LAMP3 other 1 1 1 3.46640595766125 0.479982579897414 0.326961068057003 53.1718584290193 66.5012542753948 0.799561737720377 0.424559727615242 -195.264015790741 180.916481271227 -1.0793047400585 0.281267281136596 FAP other 1 1 1 0.799561737720377 -1.0793047400585 0.00109311872830223 -5.28409882760287 112.25015870544 -0.0470743105269816 0.962483366429266 -715.748110349404 223.368027249773 -3.20434450338341 0.00149011745666643 NEBL other 1 1 1 -0.0470743105269816 -3.20434450338341 4.37959315604287e-13 220.770005327559 38.3932040770178 5.75023654927806 2.11829635283922e-08 -236.715331036715 118.452461581514 -1.99839942434475 0.0465380995181547 ACER3 other 5.81215807738449e-09 1 0.000270824188710494 5.75023654927806 -1.99839942434475 3.0876952913678e-24 399.51512382887 67.5491505156874 5.91443594447703 8.57256400166941e-09 -653.185401577644 129.356862764034 -5.04948394403434 7.46433882960548e-07 UBE2K other 4.58738889438514e-20 0.0111965082444082 0.000110946123309606 5.91443594447703 -5.04948394403434 3.11984300887165e-25 132.331816363194 29.0367384693922 4.55739257708594 7.47730230171038e-06 -252.394693611781 44.0930837554119 -5.72413340404667 2.46680940065803e-08 PIK3C3 essential 4.65542973783828e-21 0.000374116313703797 0.0846654939622667 4.55739257708594 -5.72413340404667 9.23484764844015e-05 69.1102504632835 20.1947149572286 3.42219489651899 0.000702130134208907 -18.6193289267323 38.6729507527164 -0.481456122802433 0.630522455833099 N4BP2 other 0.798999018543042 1 1 3.42219489651899 -0.481456122802433 0.000150851410282292 48.8325152261937 12.9116075903772 3.78206314623345 0.000186083589617534 -83.3092912237586 62.4562470600096 -1.33388244003379 0.183205996372361 TIGAR other 1 1 1 3.78206314623345 -1.33388244003379 2.62288470879905e-13 176.037266197788 23.4601891282092 7.50365929429427 6.44022019300676e-13 -176.124430931726 114.843135943712 -1.53360868705336 0.126132865520152 TULP3 other 3.49866591306705e-09 1 9.05752567944471e-09 7.50365929429427 -1.53360868705336 0.000169316158136554 57.6716615492106 37.3563198373751 1.54382609958034 0.123618785525973 -285.260912219695 81.6921320978075 -3.49190191141248 0.000547007511077618 SYNJ2 other 1 1 1 1.54382609958034 -3.49190191141248 0.0133417868508588 31.9209884182595 10.9279644756115 2.92103698630237 0.00373741485587427 -11.6072564580511 63.1116842621928 -0.183916125734018 0.854196106116029 ADCY2 other 1 1 1 2.92103698630237 -0.183916125734018 2.48724107433048e-14 371.617050585447 51.7535117490675 7.18051853924952 4.97204525529452e-12 -299.590945384046 155.402018848947 -1.92784461619673 0.0547675578167768 PPP2R5C other 3.38115551644485e-10 1 6.90865688223174e-08 7.18051853924952 -1.92784461619673 0.132345126831637 19.6808663678528 9.89149005407928 1.98967660688657 0.0474854769609966 29.1274489757151 30.9267597624801 0.941820261786756 0.347001841074039 RBFOX1 other 1 1 1 1.98967660688657 0.941820261786756 2.13332904415294e-17 1990.20697065944 241.156116818548 8.25277416519741 4.13270747667752e-15 -1000.55352241637 536.010391142749 -1.86666814477838 0.0628652088444127 GNB1 other 3.02207392394705e-13 1 5.96060399361199e-11 8.25277416519741 -1.86666814477838 0.0702193750875545 30.963984238153 22.2100757037612 1.394141319064 0.164248257744568 -58.5372619667518 52.2790378134829 -1.11970809745192 0.263683164920745 EDN1 other 1 1 1 1.394141319064 -1.11970809745192 1.11023980664162e-13 123.658031729567 24.1389998272099 5.12274877230734 5.21446603163159e-07 -127.819069249312 48.0345046579 -2.66098443524369 0.0081841922516828 MLLT10 og 1.49071898837771e-09 1 0.00629698917979831 5.12274877230734 -2.66098443524369 0.126190929198791 0.13634834150136 7.73720747255681 0.0176224228166268 0.985951050918472 -66.5773092081727 33.4895681844363 -1.98800142305548 0.0476633392511138 ZCWPW1 other 1 1 1 0.0176224228166268 -1.98800142305548 0.639434915791904 0.087175193772934 4.86264460535322 0.0179275272712639 0.98570787645081 -18.5205312916551 19.9855506339295 -0.926696073122587 0.354784924885183 ADCYAP1R1 other 1 1 1 0.0179275272712639 -0.926696073122587 1.6195913169886e-26 265.527779031379 57.1346561788624 4.64740311379722 5.24474529807073e-06 -955.508462240247 133.777949233207 -7.14249596227974 8.39421686676573e-12 VDAC3 other 2.42695758850742e-22 1.28565825531384e-07 0.0599998862099292 4.64740311379722 -7.14249596227974 5.8495335310586e-27 291.89855071803 91.8595774982415 3.17766049733483 0.00162959713474558 -1209.01078365743 170.813238438614 -7.07796886651686 9.29894270769272e-12 PCM1 other 8.77605515664722e-23 1.42404008625606e-07 1 3.17766049733483 -7.07796886651686 0.701826159710849 -9.9191244647026 21.8521243217419 -0.45392037490989 0.650193838967465 -40.7330363710533 51.8627940531042 -0.785399959927829 0.432800218897079 TNRC6C other 1 1 1 -0.45392037490989 -0.785399959927829 4.62973662747451e-05 168.436774872945 37.9295240024314 4.44078272277152 1.24697447848205e-05 -96.9847122384507 238.214465180648 -0.407131918562977 0.684191172689038 CBFA2T2 other 0.414870699187991 1 0.13896283588204 4.44078272277152 -0.407131918562977 0.149574019442225 4.44104442469892 2.31368989365145 1.91946398559493 0.0558174539583252 2.77146406877916 4.64157171096673 0.597096035860216 0.550866820320462 BRINP1 other 1 1 1 1.91946398559493 0.597096035860216 3.0381020528209e-18 263.861932959586 27.6429482703967 9.54536145633064 4.11340722369081e-19 28.3058591834711 179.004003162117 0.158129755108524 0.874456850120916 ITCH other 4.34114402327578e-14 1 6.08208392094923e-15 9.54536145633064 0.158129755108524 4.10822659879566e-05 0.718198216602406 3.76798329518349 0.19060546725896 0.848955571280016 -23.6961142444358 5.61074603250294 -4.2233446509902 3.14138943712556e-05 PKD2L2 other 0.370151216551489 0.456286815742487 1 0.19060546725896 -4.2233446509902 0.324515858330123 138.264507348341 100.249193923044 1.37920817053632 0.168821578583474 -250.313364296527 615.168258896911 -0.406902275395965 0.684359659213221 TP53INP2 other 1 1 1 1.37920817053632 -0.406902275395965 3.54829264194676e-12 784.808997264643 118.170912158986 6.64130438638547 1.3635663820761e-10 -435.380754075997 268.054715913554 -1.6242234448 0.105328305800362 SDF4 other 4.61668355643694e-08 1 1.84789721745511e-06 6.64130438638547 -1.6242234448 0.107450065492661 9.03277965830693 4.38296228862898 2.06088463999366 0.0401425609045508 -10.5102974418264 39.0229462628789 -0.269336337933675 0.78784890331103 MYH7B other 1 1 1 2.06088463999366 -0.269336337933675 5.52984428021396e-05 -231.985153358404 291.756993918193 -0.795131421677083 0.427133871433626 8384.52386159542 1951.70850392996 4.295991868003 2.31784545052061e-05 BPIFB2 other 0.490828978311791 0.337872331322389 1 -0.795131421677083 4.295991868003 0.00677475872255412 -83.955560281697 80.1110372179909 -1.04798992994242 0.29543413007362 -564.806312898902 177.461441051287 -3.1826987854543 0.00160237056008568 TP73 other 1 1 1 -1.04798992994242 -3.1826987854543 2.23686894039956e-14 473.001155514032 103.613956411602 4.5650332435435 7.13127922306457e-06 -580.347822692956 192.863521712442 -3.00911140447933 0.00282821918996608 TOLLIP other 3.04303650651956e-10 1 0.0808972315064445 4.5650332435435 -3.00911140447933 7.90667975070796e-06 51.4920125964249 11.5208014867962 4.46948180258457 1.08965178940378e-05 -56.0321124002795 46.2016264342289 -1.21277359099132 0.2261109376669 UBE2D4 other 0.0761808593980712 1 0.121888449162707 4.46948180258457 -1.21277359099132 0.919775010239976 1.12816213973915 5.48237476128287 0.205779828789953 0.83709374829821 -9.26958191540639 27.8888484356999 -0.332375929281491 0.739823029223486 RUNX1T1 other 1 1 1 0.205779828789953 -0.332375929281491 0.41874340482358 -1.52469728282001 1.33002395573934 -1.14636828625575 0.252499281088944 -5.13914692649454 6.74111710023014 -0.762358352493105 0.44640771344624 CDH17 other 1 1 1 -1.14636828625575 -0.762358352493105 8.4470642755747e-38 235.672035863155 15.4756791523381 15.2285423820995 6.93730317968769e-39 98.8345740220736 67.0913415985045 1.4731345605448 0.141799295308878 THOC1 essential 1.28834624331065e-33 1 1.06008929888808e-34 15.2285423820995 1.4731345605448 0.00254289836738493 30.0144783854174 8.60808717646062 3.4867767681877 0.000558795278922612 8.18556522200034 32.5421631237936 0.251537219294908 0.801563857148596 FKBP7 other 1 1 1 3.4867767681877 0.251537219294908 1.07254041435595e-07 65.809232330652 11.7567729326581 5.59755918631771 4.76544295862828e-08 -40.9173538719048 44.1075706381166 -0.927671900309675 0.354294865317893 OSBPL6 other 0.00118140326641308 1 0.000601017665942198 5.59755918631771 -0.927671900309675 4.48434984959114e-07 155.839137615611 29.4224142981755 5.29661284884004 2.21087809309234e-07 -208.894955449402 193.218997906707 -1.08113051880262 0.280460842906583 SLC1A3 other 0.00475699832044628 1 0.00271473721050808 5.29661284884004 -1.08113051880262 2.72263068640809e-17 772.66355237392 215.531434433682 3.58492279515574 0.000389750628467991 -2257.1180799345 378.15084512482 -5.96882992338539 6.34039196418329e-09 XRCC5 essential 3.8508888428556e-13 9.64563829511204e-05 1 3.58492279515574 -5.96882992338539 0.902899054829359 7.18873183603183 21.1315791170237 0.340189050530567 0.73394162551072 -35.8223740445721 122.464604789279 -0.292512061801127 0.770088328806925 LXN other 1 1 1 0.340189050530567 -0.292512061801127 0.052875634272165 -0.586608960570703 15.5174234973369 -0.0378032448925155 0.96986812928793 -59.024254604993 27.0276881277198 -2.18384400197578 0.029699491403908 SP140 other 1 1 1 -0.0378032448925155 -2.18384400197578 0.291032352952003 36.6087692107197 28.1153147502009 1.30209352219534 0.193820867915476 -45.2903553110485 71.3490152162255 -0.634771975111284 0.526030718143458 MKNK1 other 1 1 1 1.30209352219534 -0.634771975111284 0.464541842470704 236.914906810918 191.092638396478 1.23979086164151 0.215961156156609 193.123893844614 335.41648093424 0.575773418487677 0.565173024675288 TNS1 other 1 1 1 1.23979086164151 0.575773418487677 1.25639616410198e-13 332.81112699899 72.524143944651 4.58897008495523 6.40553696600592e-06 -651.731657477484 150.896178676969 -4.31907330716889 2.09300016903349e-05 SAR1A other 1.68520417490999e-09 0.305473374670438 0.0728821995992154 4.58897008495523 -4.31907330716889 0.0901261990942946 -7.81427140121482 10.7201444110668 -0.728933408130942 0.466577212748002 37.8676094886457 22.3063825059752 1.69761320458403 0.0905560477824857 CDC14A other 1 1 1 -0.728933408130942 1.69761320458403 0.133621645843968 66.7655751222874 41.1400189979091 1.62288634639864 0.105607720315558 -93.8766150310203 108.239703798983 -0.867302955719122 0.386432076399873 RAPGEF3 other 1 1 1 1.62288634639864 -0.867302955719122 0.577432689400689 -58.4173393808418 90.150839287605 -0.647995513324897 0.517456907491817 -247.061466533714 256.052789946764 -0.964884884031459 0.335337969031126 CEACAM1 other 1 1 1 -0.647995513324897 -0.964884884031459 0.0211856744729884 36.4150945032134 27.4504948634963 1.32657333444426 0.185601720879052 -154.068255371097 71.2373150837204 -2.16274652111791 0.0313057172501214 SENP1 other 1 1 1 1.32657333444426 -2.16274652111791 0.583423539687586 9.38120978120974 23.3852368763319 0.401159493522361 0.688571280294717 -40.7770948987368 55.3019335381049 -0.737353873362131 0.461449174036461 DUSP13 other 1 1 1 0.401159493522361 -0.737353873362131 0.000120905860926606 317.070113345047 112.076235499509 2.82905748869872 0.00496603105122057 -651.469831062589 277.686016986228 -2.3460663886972 0.0195884671142461 CIC og 1 1 1 2.82905748869872 -2.3460663886972 0.00934390124091037 -12.9376591953715 19.388470978118 -0.667286203743092 0.505074783793896 -147.67854776787 48.0379025702577 -3.07420890310277 0.00229406694805576 LIPE other 1 1 1 -0.667286203743092 -3.07420890310277 6.80478944288384e-21 302.029776016334 179.995631298783 1.67798392570418 0.0943296181494986 -2352.61853412004 347.047445054299 -6.77895362045368 5.86569052637267e-11 FDFT1 other 9.93703402344327e-17 8.9762662125081e-07 1 1.67798392570418 -6.77895362045368 0.00368418563297582 95.3552726330038 65.9360177808235 1.44617882368893 0.149115026689621 -414.408214995534 163.366569834246 -2.53667696772967 0.0116703860611683 PAFAH1B3 other 1 1 1 1.44617882368893 -2.53667696772967 0.610476693120077 -0.982827211489815 80.6244957258239 -0.0121901811929723 0.990281551679226 -279.986524651856 291.93973946823 -0.95905588311428 0.338261489636432 KIF22 other 1 1 1 -0.0121901811929723 -0.95905588311428 0.610142450786073 -30.3199953369707 37.1489935968678 -0.816172725054039 0.415012301106683 -68.9670576388895 81.3143208939536 -0.848153890737564 0.396990221240818 SCGN other 1 1 1 -0.816172725054039 -0.848153890737564 8.5603387070047e-09 183.45859937682 36.6463270755218 5.00619336280942 9.22806890323647e-07 -117.584659719739 80.839819970482 -1.45453886169803 0.14678638954714 CARMIL1 other 9.97279459366047e-05 1 0.011022928304916 5.00619336280942 -1.45453886169803 0.0204037028786112 210.295006687143 112.201679627184 1.87425898957927 0.0618056774746312 -404.035383291754 262.468949864029 -1.53936449816659 0.124703556981746 PGM1 other 1 1 1 1.87425898957927 -1.53936449816659 1.01474082996514e-10 379.765832007592 62.8702623509915 6.04046838372391 4.31553102065532e-09 -465.661342808899 200.786834410934 -2.31918265047133 0.0210224972102545 DDX1 essential 1.26862898562242e-06 1 5.64126215020064e-05 6.04046838372391 -2.31918265047133 7.26168598283169e-16 633.000650620348 112.391901381355 5.63208418792137 3.91903240773362e-08 -1182.32603883864 251.708827277718 -4.69719735944794 3.93022950343919e-06 DNM2 other 1.01046360451103e-11 0.0583992801916029 0.00049579678990238 5.63208418792137 -4.69719735944794 0.10076721478976 11.2463386995897 67.3384763740352 0.167012075490413 0.867466033622936 -324.460517736079 158.898135523719 -2.04194037058192 0.0419770453391979 EPB41L2 other 1 1 1 0.167012075490413 -2.04194037058192 0.359193010730674 -189.073449387594 131.925938948645 -1.43317872811348 0.152789166450312 -108.791332385946 313.940380288852 -0.346535008608477 0.729169864336429 MOXD1 other 1 1 1 -1.43317872811348 -0.346535008608477 7.05072375208779e-06 58.5028340466379 28.5696669805465 2.04772544553891 0.0414080615051587 -267.472097829148 67.9864186533483 -3.93419896395698 0.000102538068235583 STX7 other 0.0682157523014493 1 1 2.04772544553891 -3.93419896395698 0.00135544664699168 39.6041603474577 14.2132045957147 2.78643426827181 0.00565232546034578 -65.9106816735365 40.8985189013213 -1.61156646852087 0.108057789557554 RABL2B other 1 1 1 2.78643426827181 -1.61156646852087 2.43639741274631e-08 526.409469747777 117.094740967931 4.49558592808147 9.72157511665826e-06 -622.476745651019 255.812301273637 -2.43333390361541 0.0155094186770688 KEAP1 other 0.000277700577104824 1 0.109260782736122 4.49558592808147 -2.43333390361541 0.71368211226541 0.557465958919888 7.63936254523921 0.0729728371469025 0.94187389964435 15.1280917930142 18.5273494508938 0.816527579031782 0.414813570500443 DDX43 other 1 1 1 0.0729728371469025 0.816527579031782 0.569651723205215 28.6428725352871 28.5239343344765 1.00416976842731 0.316055500973922 -5.67050964335748 74.4392754910279 -0.0761763142635764 0.939326429130936 PTPRH other 1 1 1 1.00416976842731 -0.0761763142635764 0.727580835314723 -0.299607721834007 4.72483788620593 -0.0634112172840269 0.949479660735574 -8.67033980256427 11.0044372823546 -0.787894880955613 0.431356369433019 DCT other 1 1 1 -0.0634112172840269 -0.787894880955613 6.68757031907416e-16 223.928822672791 28.694434517776 7.80391133110041 8.59709567053191e-14 -281.326524028229 130.451438150553 -2.15656130753846 0.031784471502134 SLC35C2 other 9.30976664118314e-12 1 1.22448433635386e-09 7.80391133110041 -2.15656130753846 4.88041320566263e-10 249.087088025219 40.1246977495364 6.20782465652585 1.68130640875581e-09 -152.587821348951 166.071786046358 -0.918806408852356 0.358895417551287 CRYBG3 other 5.97557792901332e-06 1 2.22319146429781e-05 6.20782465652585 -0.918806408852356 6.38104343248059e-09 23.9488765077936 6.56920684114001 3.64562679893294 0.000312094647054515 -94.086464593006 21.1191652439568 -4.45502762567421 1.16804696878822e-05 RFX3 other 7.47411617246452e-05 0.171621141124054 1 3.64562679893294 -4.45502762567421 4.49916439901631e-05 302.078317775231 69.524112491383 4.34494317079807 1.88161779072978e-05 -100.130214401196 181.612757641063 -0.551339100302039 0.581792103610784 RIF1 other 0.403575046591763 1 0.207218781201882 4.34494317079807 -0.551339100302039 1.16938493641128e-60 646.108057435746 31.3416676364111 20.6149865709485 2.60070176339209e-60 -331.226755839941 166.921709275132 -1.98432401200727 0.0480899848838017 RAB21 other 1.79453812341676e-56 1 3.99155706645418e-56 20.6149865709485 -1.98432401200727 0.63395073614659 -5.2929154822977 10.4799283726125 -0.505052639112481 0.613869510072226 -21.8520342817949 23.3741880598914 -0.934878859783441 0.350555660718684 SLC4A4 other 1 1 1 -0.505052639112481 -0.934878859783441 1.83862603073286e-19 662.894989847838 95.4199619188518 6.94713115072908 2.16663195049355e-11 -1786.3025055289 306.201192114665 -5.83375424893829 1.35179546761253e-08 SMARCA2 other 2.65571143879055e-15 0.000205297177666314 2.97911893192863e-07 6.94713115072908 -5.83375424893829 0.00345302037371228 -27.1368551649734 22.4750239392599 -1.20742274794957 0.228163855244028 -173.006486019959 51.1914798752427 -3.37959532409666 0.000816027291678848 SESN1 other 1 1 1 -1.20742274794957 -3.37959532409666 0.00393813910290279 620.48456229568 186.91882511638 3.31954024378953 0.00100572404280301 257.245787916942 402.332944929927 0.639385342807922 0.523029719265202 COL5A3 other 1 1 1 3.31954024378953 0.639385342807922 0.000745850420209387 287.814052407272 132.475684970718 2.17258021704806 0.030561970449697 -1102.80514860936 455.871952608971 -2.41911164373672 0.0161283615573409 SRCAP essential 1 1 1 2.17258021704806 -2.41911164373672 3.80426928456949e-50 416.279447843594 23.6588647352559 17.5950728195028 1.16030768360162e-48 -142.443132255266 75.9209335272614 -1.8762036455218 0.0615577322379226 PUM3 other 5.83004267860275e-46 1 1.77828755588784e-44 17.5950728195028 -1.8762036455218 0.507137173674506 2.25761326837913 4.36982658649429 0.516636810109736 0.605766567405721 -6.64436292252639 8.50397836806167 -0.781324062097874 0.43518958013552 CHRNA3 other 1 1 1 0.516636810109736 -0.781324062097874 2.34377560997147e-17 84.7818059676426 15.8148320087773 5.36090461919469 1.59466060852617e-07 -147.540707234693 34.7727539254717 -4.24299747874203 2.89661425484619e-05 CNOT4 other 3.3187862637196e-13 0.421225644939733 0.00197004371577324 5.36090461919469 -4.24299747874203 1.43307343694641e-17 360.154811597302 41.0145917229394 8.78113852821476 9.95512483167356e-17 -143.868048488529 126.506609099599 -1.13723741006497 0.256289882232922 PSEN1 other 2.03467766577652e-13 1 1.45175585420295e-12 8.78113852821476 -1.13723741006497 2.4129831911222e-10 232.205921219107 36.5359450515302 6.35554714382247 7.16970438025512e-10 -133.277938571611 152.815847749798 -0.872147362555119 0.383783941956901 CPOX other 2.98582540069461e-06 1 9.58087596333491e-06 6.35554714382247 -0.872147362555119 2.78234317509705e-07 421.764070351759 82.8716854297206 5.08936276805226 6.14895865594724e-07 -330.166360396755 347.917093967418 -0.948979990122804 0.34334915496586 CLDND1 other 0.00299463595935696 1 0.00740273132589488 5.08936276805226 -0.948979990122804 0.000271782220058 49.4495911920625 12.772845066411 3.8714625390784 0.00013147232064691 -4.78813483991149 38.0162419382732 -0.125949715063524 0.899851824234344 MOK other 1 1 1 3.8714625390784 -0.125949715063524 1.07195130305663e-08 4842.61846490817 848.283232407401 5.70872826422016 2.62355884782294e-08 -1743.00915171462 2536.22853125631 -0.687244516901332 0.492432718755754 HSP90AA1 other 0.000124164119433049 1 0.000334398810743512 5.70872826422016 -0.687244516901332 0.000303108842089127 68.0950459952387 17.781724797648 3.82949611301182 0.000154757110163074 -53.5049978274351 93.0877599812578 -0.574780162700313 0.565847672624199 RBL1 other 1 1 1 3.82949611301182 -0.574780162700313 2.19845451384895e-24 742.858335719972 68.9325288688692 10.7766006544329 2.92365441410956e-23 -605.807912770964 376.682937584746 -1.60827011877773 0.108777805562557 DLGAP4 other 3.2675629439337e-20 1 4.38694344837139e-19 10.7766006544329 -1.60827011877773 0.507778156771846 0.284023450802153 6.2132526876748 0.0457125221006333 0.96356920034447 -9.83967308771956 11.3571658935914 -0.866384552265092 0.386958121027874 IGSF9B other 1 1 1 0.0457125221006333 -0.866384552265092 0.398042814780191 -0.238578009779713 2.95555921363391 -0.0807217830991709 0.935713673897027 -7.68503220599257 5.85514674869873 -1.31252597685968 0.19028332150252 CROCCP3 other 1 1 1 -0.0807217830991709 -1.31252597685968 6.80757910527875e-16 169.638982109633 19.4013421583672 8.74367251115527 1.68356359994811e-16 -13.1470956264784 90.5253388452732 -0.145231112019912 0.88462658240681 NDC80 essential 9.47478859872697e-12 1 2.45227873968442e-12 8.74367251115527 -0.145231112019912 6.91213376846124e-13 163.10281828631 23.0118636420896 7.08777093516183 8.88800569711317e-12 -31.4942195525145 49.2864801584527 -0.63900322058428 0.523282277784812 AP4E1 other 9.13645841515207e-09 1 1.23063326882229e-07 7.08777093516183 -0.63900322058428 7.35621824916585e-06 46.604184503424 18.9416879859732 2.46040292385429 0.0144077464096784 -91.8455012453304 34.5376909120017 -2.65928320104962 0.00822596875759748 RSBN1 other 0.0710610682869422 1 1 2.46040292385429 -2.65928320104962 0.00275022837066346 -1.66025643231364 40.7175369253742 -0.0407749721049312 0.967500799893424 -228.243273830374 74.1878067647237 -3.07656047245359 0.00227540454906836 MAGI3 other 1 1 1 -0.0407749721049312 -3.07656047245359 0.83499713505986 -15.7419325230431 31.8092366822694 -0.494885579314064 0.621022636635329 -33.8407470387046 68.9208515287411 -0.491008835324567 0.623758873673146 CXCL2 other 1 1 1 -0.494885579314064 -0.491008835324567 0.0677117742286174 -59.6057076659469 36.8725453679088 -1.61653357725131 0.106964362868026 -142.327542609793 63.912411971042 -2.22691552736704 0.0266484410889117 COL4A4 other 1 1 1 -1.61653357725131 -2.22691552736704 0.000184243669729654 65.4885690257576 34.1167701896795 1.91954187520272 0.0558075662970709 -140.967983238563 50.9452249224331 -2.7670499728521 0.00598671181147386 TCF7 other 1 1 1 1.91954187520272 -2.7670499728521 1.01799385798969e-07 117.641391710869 36.6821255661861 3.20704947968752 0.00147705002643719 -322.770033264407 83.5510697464636 -3.86314662689365 0.000135581105088752 OSTM1 other 0.00112294902474842 1 1 3.20704947968752 -3.86314662689365 1.47786611352761e-15 350.890927742034 46.7387937453638 7.50748788369919 6.07866731097563e-13 -443.665409202094 190.992786472347 -2.32294327653223 0.0208108157786585 PCNP other 2.04920915301739e-11 1 8.55025343961832e-09 7.50748788369919 -2.32294327653223 1.7040725739991e-18 147.776461693941 15.5788627854175 9.48570275824409 5.95550561383183e-19 20.8258555583065 49.8202843239044 0.418019604683669 0.676215803146291 EXD2 other 2.44074314773891e-14 1 8.79568624106823e-15 9.48570275824409 0.418019604683669 1.29346302377797e-05 160.925654592608 39.549489165394 4.06896923294319 5.96632717637812e-05 -191.249896005305 125.244040996799 -1.52701792822377 0.127753676415316 ARG2 other 0.122322798158682 1 0.631893711250207 4.06896923294319 -1.52701792822377 0.448360713494097 40.9049662373654 104.949784584419 0.389757505452166 0.696975146205247 184.651352024846 146.345973930626 1.26174534949884 0.207959349215933 MEF2C other 1 1 1 0.389757505452166 1.26174534949884 0.0841521881684194 -164.591021764455 73.7159987345216 -2.23277205206441 0.0262597104362132 -24.451843301082 253.642102593274 -0.0964029356762256 0.923261286018553 PTPRC other 1 1 1 -2.23277205206441 -0.0964029356762256 0.559985814802882 72.8229962571038 68.9764510112706 1.05576606493142 0.291871525730391 55.2295583246671 230.124613050271 0.239998484267314 0.810485096497101 CACNA1S other 1 1 1 1.05576606493142 0.239998484267314 0.195869221668597 3434.79632313311 1897.32499551271 1.81033630572338 0.0711844608554074 284.96265003035 6325.32698873486 0.0450510543625422 0.964094802661008 PKP1 other 1 1 1 1.81033630572338 0.0450510543625422 3.63185188667678e-20 178.546874041822 17.9176577611827 9.96485569830624 1.50613895226443e-20 -33.1438569326056 73.5530752742189 -0.450611436830335 0.65257477880777 UBA5 other 5.27599123577536e-16 1 2.24143598875992e-16 9.96485569830624 -0.450611436830335 0.0078326208952998 -5.67843219159036 49.3362562523562 -0.115096535954107 0.908441706007235 -379.7205165692 123.593628118723 -3.07233085029629 0.00230872156862765 STK17B other 1 1 1 -0.115096535954107 -3.07233085029629 0.197871616368286 10.643836571627 17.9594693510805 0.592658745286736 0.553830755611047 -55.0016540110402 34.1611228729996 -1.61006575268381 0.108375671506147 CDC14B other 1 1 1 0.592658745286736 -1.61006575268381 6.10789652222184e-05 28.6889895229688 7.12831706729837 4.02465115568182 7.13258372735909e-05 -19.6943596181996 13.664095636877 -1.44132185119138 0.150474674046291 ZNF510 other 0.539327262912188 1 0.750490459792723 4.02465115568182 -1.44132185119138 8.2606125659064e-05 32.1857149176674 10.0142296154653 3.21399809606542 0.00144330358300902 -41.1266041595131 22.6669406762899 -1.81438707352918 0.0705603591077961 ZNF506 other 0.717599413600289 1 1 3.21399809606542 -1.81438707352918 6.61247260519547e-12 196.557329963235 26.9253529154505 7.30008370105502 2.29255465131451e-12 123.163455225841 90.843835002056 1.35577120035777 0.176127985266886 JMJD4 other 8.54529834769411e-08 1 3.2036158697469e-08 7.30008370105502 1.35577120035777 1.01059439586556e-05 54.4926005803627 11.2854771171178 4.82855975116093 2.13470575044496e-06 -33.8603665696638 38.7456937512934 -0.873913028555166 0.382820981038491 DUSP12 other 0.0964410231974502 1 0.0249781919859565 4.82855975116093 -0.873913028555166 0.00025534994355893 158.911921949297 64.3202546634939 2.47063577065546 0.0140080556900885 -462.680681353042 165.003440530978 -2.80406687196426 0.00535449882555968 AACS other 1 1 1 2.47063577065546 -2.80406687196426 4.95692818166746e-10 116.909622378299 32.4237435343597 3.60567934589073 0.000361168620541461 -193.650335045519 46.2314853257717 -4.18871108468516 3.63478554987777e-05 KIAA0141 other 6.06777578717914e-06 0.526931152201186 1 3.60567934589073 -4.18871108468516 0.34979183748093 2.07230743650487 25.955779010249 0.0798399244995342 0.936414633088477 -84.4993939202827 66.235072071786 -1.27575001094136 0.202972071960486 CADPS2 other 1 1 1 0.0798399244995342 -1.27575001094136 0.812856231791037 2.14125265023791 6.00903688324074 0.356338743103721 0.721823200964621 5.91860148867003 9.50181028688554 0.62289198689211 0.533801943422639 PCDHB4 other 1 1 1 0.356338743103721 0.62289198689211 0.253292459607711 17.252778815452 10.686887779936 1.61438757201541 0.107480808795387 15.5569448580889 17.8160011943169 0.873200708083211 0.383242898513884 PCDHA6 other 1 1 1 1.61438757201541 0.873200708083211 0.000536833187006787 549.034495145524 141.292526229062 3.88579997681855 0.000124133342306919 401.315981181885 223.419294184679 1.79624585533851 0.0734044736496918 PCDHGA2 other 1 1 1 3.88579997681855 1.79624585533851 9.89066984161077e-05 8.54946235713137 21.6144094621255 0.395544572805119 0.692706254984504 -216.370838142915 52.2995036286551 -4.13714898097741 4.50644898510997e-05 HSPB11 other 0.853169180537345 0.651091749368689 1 0.395544572805119 -4.13714898097741 5.28517856673822e-14 165.674337304217 41.9167182821492 3.95246441262487 9.52946653295168e-05 -222.593813802571 68.1514875070385 -3.26616222103123 0.00120874284373742 PHLPP1 other 7.13710513652329e-10 1 0.989825688777691 3.95246441262487 -3.26616222103123 6.02652782748639e-09 235.296180757076 115.31402666263 2.04048186995909 0.0421228544405124 -610.625128974012 174.974050600496 -3.48980392737322 0.000551159548583178 ATP8B1 other 7.06911714164153e-05 1 1 2.04048186995909 -3.48980392737322 0.0205097820799352 150.066723399286 54.29576281874 2.76387540405807 0.00604281412430414 34.8266714398822 122.690099250804 0.283858857825921 0.776702120265095 IL12RB2 other 1 1 1 2.76387540405807 0.283858857825921 0.00646249777358117 78.1388408907123 27.0604158113919 2.88756985241215 0.00414748731441473 17.3558821825501 60.1421859310818 0.28858083413261 0.773089590585257 SMARCD3 other 1 1 1 2.88756985241215 0.28858083413261 1.27051810652233e-32 160.511000640814 11.8734432924232 13.518487997769 3.56912234564864e-33 -66.8811629803677 79.7341364126485 -0.838802124026744 0.402214424010381 WDR70 essential 1.92686776035176e-28 1 5.43434568348461e-29 13.518487997769 -0.838802124026744 6.24461102410671e-06 32.7069706900406 6.68025339226793 4.89606737491385 1.56033144590549e-06 10.1632541373598 16.2865115811215 0.624028914156209 0.533057400379672 STRADB other 0.0606851299322691 1 0.0184134713931307 4.89606737491385 0.624028914156209 1.11849622577797e-11 568.596565502634 108.478410906886 5.24156429605791 2.91789223976282e-07 -950.886663123988 267.813631531758 -3.55055363569583 0.000442883628487633 BZW1 other 1.43659655238923e-07 1 0.00356508073854221 5.24156429605791 -3.55055363569583 9.98137110417409e-31 38.9145353271129 2.96424375681041 13.1279808678709 1.36894972235705e-31 44.5742125460804 16.9586386578605 2.62840747098646 0.00900718175263558 PGR other 1.50968237950633e-26 1 2.08272010759402e-27 13.1279808678709 2.62840747098646 0.000131799148853354 67.8009082616719 15.8780534895977 4.27010201887094 2.58293189587711e-05 4.25929881976128 104.814218665876 0.040636650961822 0.967611066037052 C1QTNF3 other 1 1 0.281694552564357 4.27010201887094 0.040636650961822 2.49501646226766e-13 205.44974552135 43.6928460569317 4.70213694144917 3.85168793550869e-06 -127.891417628062 67.7811989274185 -1.88682731571348 0.0601000946875483 ME2 other 3.32934996724997e-09 1 0.0444138135843507 4.70213694144917 -1.88682731571348 1.10798884817199e-17 123.684156083787 13.2063568990902 9.36550155571728 1.47774945849179e-18 -0.522844342557036 85.5484647708691 -0.00611167417156357 0.995127476354964 C5orf22 other 1.57489534879166e-13 1 2.17894157654614e-14 9.36550155571728 -0.00611167417156357 2.34399769116415e-05 100.737010958378 27.4254685873518 3.67311904398366 0.000281449405686905 -168.543003134398 70.8799405992528 -2.3778660324692 0.0180095070430657 CCNT2 other 0.216374426871363 1 1 3.67311904398366 -2.3778660324692 0.00395987738519563 -28.3466472270962 60.6831658510192 -0.467125385262347 0.640733121507974 -486.472885038533 145.070588499199 -3.35335294404779 0.000895794321983943 FAM135A other 1 1 1 -0.467125385262347 -3.35335294404779 0.104335083942446 -28.2500416736124 14.2680631734023 -1.97994929867388 0.0485820195051781 14.9494082347057 34.0902958335373 0.438523863439132 0.661308131759477 COL19A1 other 1 1 1 -1.97994929867388 0.438523863439132 0.00275733546400467 87.3986067886533 25.3736794143296 3.44445932974528 0.000652067376919932 18.9847664212264 116.3193984594 0.16321238480143 0.870458951899826 EPB41L3 other 1 1 1 3.44445932974528 0.16321238480143 0.237397799950335 66.3871681119193 82.3065993067695 0.806583781508017 0.420516800718021 -306.791855115961 229.912069697421 -1.33438777494247 0.183043663420241 COBLL1 other 1 1 1 0.806583781508017 -1.33438777494247 0.284545455760792 9.43630353397234 6.62409179828377 1.4245429896393 0.155266883131118 -14.6009405045329 21.2840308057107 -0.686004480909478 0.493208555189441 KCNK2 other 1 1 1 1.4245429896393 -0.686004480909478 0.00183325953269127 81.9234090009715 27.6600604462251 2.96179428675659 0.00328742290912406 192.921246497424 93.3455895218317 2.06674195841147 0.0395625261016589 SERTAD4 other 1 1 1 2.96179428675659 2.06674195841147 0.00794908084638155 37.4252177493175 12.3716539033618 3.02507797596471 0.00268706664310901 -32.0843509624673 41.7511497928407 -0.768466284681074 0.442776959615149 TRAF5 other 1 1 1 3.02507797596471 -0.768466284681074 9.70513350874097e-09 89.4996647485879 23.3249111167225 3.83708492181229 0.000150003274179403 -114.764218898979 33.9371838524224 -3.38166594488326 0.000809824553299208 MRPL22 other 0.000112754241104553 1 1 3.83708492181229 -3.38166594488326 4.58293189084462e-09 171.587042740209 30.3695982852655 5.64996089604049 3.54940090390582e-08 -41.159005184562 44.1870339986998 -0.931472458318273 0.352311431482262 GEMIN5 essential 5.40740133800757e-05 1 0.000449673600515828 5.64996089604049 -0.931472458318273 6.65986570887877e-05 1888.34534977725 424.283126669728 4.4506727491126 1.18464325829285e-05 244.002195680738 1008.99107005583 0.241827904053935 0.809068898480019 NFE2L1 other 0.585335597153355 1 0.132194341192899 4.4506727491126 0.241827904053935 0.57282443610944 -0.182134701746389 5.8934335696397 -0.0309046839324132 0.975364820452908 -24.2299106071769 23.2017672681933 -1.04431314766238 0.297128778718176 SEMA5B other 1 1 1 -0.0309046839324132 -1.04431314766238 8.4209892617026e-19 545.983430150729 57.3768072860669 9.51575132838235 4.6873236838496e-19 -98.9896742329242 225.717837406526 -0.43855494705383 0.661281836839043 GSK3B other 1.20942247776573e-14 1 6.9278644047297e-15 9.51575132838235 -0.43855494705383 5.39597305813456e-08 966.546401604597 162.80004440644 5.93701558945252 7.55336601019146e-09 832.625806326152 646.702112822962 1.28749510758764 0.198852154385676 ITGB5 other 0.000603755425474675 1 9.79898172502138e-05 5.93701558945252 1.28749510758764 1.30274193772161e-14 447.582749756284 58.3942438587354 7.66484365888965 2.33641615550033e-13 -641.551829199174 279.824468769967 -2.29269381630299 0.0225372925890851 ERC1 other 1.77954548692771e-10 1 3.30556157680186e-09 7.66484365888965 -2.29269381630299 4.23047000787798e-05 583.178904695104 129.346488147194 4.50865665584564 9.17534749083201e-06 -255.975756997128 553.828574494754 -0.462193120372399 0.644257904560303 XPO1 essential 0.380530777208624 1 0.103323588094259 4.50865665584564 -0.462193120372399 2.27512892844618e-22 297.133135984855 27.464762273285 10.8187040917473 1.95408295414104e-23 98.771218054602 166.884802785742 0.591852681645382 0.554369772654877 RNF13 other 3.35126491160123e-18 1 2.93366473905195e-19 10.8187040917473 0.591852681645382 0.000256897081466108 25.9216080402009 18.0183980240747 1.43861890527486 0.15124509426659 -192.295226130654 57.470124712647 -3.34600328591835 0.000918384847390926 PALB2 other 1 1 1 1.43861890527486 -3.34600328591835 2.1791197585966e-05 42.8166565879024 24.0748593572563 1.77848002983233 0.0762864244863754 -193.349408026333 51.4048491014557 -3.76130679120811 0.000201388847539954 DOPEY1 other 0.201677533658115 1 1 1.77848002983233 -3.76130679120811 5.01473227990368e-08 110.399807807521 26.3134993311897 4.19555781684511 3.52951050167683e-05 -185.531105149613 62.9482564654323 -2.94735891932919 0.00344053700306621 LYRM2 other 0.000561850604640408 1 0.381222429286115 4.19555781684511 -2.94735891932919 0.210510679921283 -14.1076986387662 26.000966863098 -0.542583616718831 0.587795379473539 -98.5264840193148 55.720943083526 -1.76821278619823 0.0779810931276801 BCKDHB other 1 1 1 -0.542583616718831 -1.76821278619823 2.61332526265923e-12 188.206556088028 81.8361976276147 2.29979595269612 0.0222144646027936 -956.494252893693 191.457075617316 -4.9958678717392 1.0471163193079e-06 KAT6A other 3.4088214726127e-08 0.0156858024632324 1 2.29979595269612 -4.9958678717392 1.75164644625718e-07 253.467410025476 48.1670444363492 5.26225789835253 2.61705661423359e-07 -118.039242853742 93.0572802877865 -1.26845790558994 0.205559358733674 ZCCHC6 other 0.00190614166281706 1 0.00320563264677472 5.26225789835253 -1.26845790558994 3.74669970173887e-07 110.222116968367 22.4062299116056 4.91926207145076 1.39206340136298e-06 -94.1132897252414 40.9911420891237 -2.29594212136414 0.022325316157334 ULK2 other 0.00399960193160624 1 0.0164764624185322 4.91926207145076 -2.29594212136414 0.120189991585952 88.5650762485144 47.6665519884643 1.85801306270166 0.0640854127625169 -248.834874969967 287.239514002888 -0.86629750726937 0.386976092347215 GRHL2 other 1 1 1 1.85801306270166 -0.86629750726937 0.0138383112713571 241.987736744805 113.446049829856 2.13306445757902 0.0336824012361956 -160.232588095479 155.810980511511 -1.02837802297021 0.304551157401297 TNPO1 other 1 1 1 2.13306445757902 -1.02837802297021 4.17922122475914e-06 1162.11133632194 262.415912085229 4.42850941121477 1.30401179865666e-05 -534.245584467522 552.576744307751 -0.966826038140288 0.334361123662804 PLOD1 other 0.0412071212761251 1 0.14516259342646 4.42850941121477 -0.966826038140288 0.820401690963499 4.35711652224073 8.10668366526277 0.537472128203426 0.591315083936683 -4.65532791230387 15.3637093632708 -0.303008069355511 0.76208059723993 P2RX5 other 1 1 1 0.537472128203426 -0.303008069355511 0.00733074709021669 14.8218448519482 22.9915010090055 0.644666254984511 0.519605354513665 -133.381796819732 43.5732728589526 -3.06109199672677 0.00239211826132306 ITGAE other 1 1 1 0.644666254984511 -3.06109199672677 2.07005819814671e-10 279.987287139914 44.0194241596587 6.36053952283425 7.48900722993421e-10 -83.7543438699719 91.4342273268243 -0.916006470646913 0.360399223399398 DIS3 essential 2.567907194801e-06 1 1.00030669570231e-05 6.36053952283425 -0.916006470646913 0.000603817121466539 46.3445345577925 12.3480043186773 3.75320038459112 0.000209854429114302 -0.0464340582151985 25.6895936189053 -0.00180750458353016 0.998559030159403 PIBF1 other 1 1 1 3.75320038459112 -0.00180750458353016 5.70860759601349e-10 37.9966860446785 9.2763971716906 4.0960607163992 5.34865996622014e-05 -59.7084008078686 17.373072583189 -3.43683597256395 0.000667570707635531 TDRD3 other 6.96849729245367e-06 1 0.569007815271709 4.0960607163992 -3.43683597256395 1.13525081471219e-22 58.3706491418082 6.38153442424716 9.14680471204922 7.2066903685289e-18 -19.4730090937949 11.8691681479706 -1.64063806755694 0.101861262643163 NUFIP1 other 1.67551667743372e-18 1 1.05772594538899e-13 9.14680471204922 -1.64063806755694 4.20310165471358e-09 120.432299114778 31.051827149353 3.87842874866986 0.000127854627552918 -159.713399313504 54.5047476728043 -2.93026582330541 0.00363260665798934 PDS5B other 4.96554429487862e-05 1 1 3.87842874866986 -2.93026582330541 6.51301621154278e-17 214.188177672755 23.3869306666662 9.15845609351555 7.26086366271445e-18 38.725891552076 164.80731660478 0.234976773785738 0.814381397288107 OXCT1 other 9.17032682585224e-13 1 1.06560435113997e-13 9.15845609351555 0.234976773785738 0.857476153781729 -6.24330649597438 16.0309933637103 -0.389452253789057 0.697200675227348 -17.6585876116712 38.7886033979638 -0.455251957140539 0.649236711312098 EPYC other 1 1 1 -0.389452253789057 -0.455251957140539 1.02899966209205e-06 40.9406852676301 49.044055213394 0.834773655838499 0.404479822359749 -555.7435886516 129.437105501871 -4.29354153507061 2.34627754683824e-05 CYLD other 0.0106470595036664 0.341923026900737 1 0.834773655838499 -4.29354153507061 0.0775027319516531 45.3182432907455 21.8458606047478 2.07445447495424 0.0388594276841688 -13.1850371587732 55.7384129041353 -0.236552073727864 0.813160029851448 SLC27A5 other 1 1 1 2.07445447495424 -0.236552073727864 4.06252308058254e-11 62.6520682442359 11.1197953744918 5.63428247861076 3.93903521039313e-08 -71.1298228731126 28.3714959646961 -2.50708749942627 0.0126827406705586 ZNF324 other 5.14884175233031e-07 1 0.000498248563762627 5.63428247861076 -2.50708749942627 0.542841323669534 -1.70698804501553 3.00966565346717 -0.567168663086898 0.570997238362088 -8.46613157332749 7.91309616621459 -1.06988862456571 0.28547577589954 ZNF671 other 1 1 1 -0.567168663086898 -1.06988862456571 4.59437480262863e-06 22.9171096650654 5.48605183218727 4.177341076256 3.80834599954843e-05 -21.1161736627942 14.256362570586 -1.48117540910201 0.139543794898692 ZNF416 other 0.045167298684642 1 0.41053969875132 4.177341076256 -1.48117540910201 2.63761063911193e-05 28.9589592886619 6.21201645858873 4.6617647396319 4.61435927642157e-06 17.0894039019926 16.3292476218704 1.04655182514986 0.296098658371514 ZNF586 other 0.242185408883257 1 0.0529359296191083 4.6617647396319 1.04655182514986 3.50136396609251e-07 54.6133378488809 13.6954594133906 3.98769666649396 8.32186171892894e-05 -86.8200054126093 34.9431494371747 -2.48460733537215 0.0134952598777736 ZNF446 other 0.00374996080768508 1 0.869800986862453 3.98769666649396 -2.48460733537215 9.27731380728585e-07 104.072039794073 26.6552077543297 3.9043792400068 0.000115307986079179 -152.129787496604 66.6439122834423 -2.28272594276252 0.023104220630208 ZNF264 other 0.0096326349261049 1 1 3.9043792400068 -2.28272594276252 7.60610375152166e-06 2507.34392655366 697.042893532534 3.59711568659244 0.000373807834087985 -3782.37826624295 1779.16106397911 -2.1259335890499 0.0342913142124586 RPS5 essential 0.0734293256171901 1 1 3.59711568659244 -2.1259335890499 2.87294701717551e-09 1614.0458112319 528.599489979659 3.05343807897736 0.00245910103520062 -3810.37511842529 1010.51304112731 -3.77073324474321 0.000195004894789602 FAT1 other 3.41564670871996e-05 1 1 3.05343807897736 -3.77073324474321 0.00070991224722546 143.028595072268 52.4150083930359 2.72877176704356 0.00671526823018984 -169.007527577314 113.634224898842 -1.48729423488183 0.137940586775646 YTHDC1 essential 1 1 1 2.72877176704356 -1.48729423488183 2.45364086890957e-11 121.044928880641 42.0475144545155 2.87876537890439 0.00428032718955445 -235.429890744178 58.6194700123857 -4.01624052033282 7.4854475303382e-05 CHMP2B other 3.12667455925147e-07 1 1 2.87876537890439 -4.01624052033282 0.534596446335262 -12.9080730900892 55.323889374177 -0.233318250688899 0.81566487567915 -156.953451800965 140.317025691561 -1.11856313250235 0.264173469199785 SMAP2 other 1 1 1 -0.233318250688899 -1.11856313250235 0.00543970073717874 106.186672693227 38.0106823005529 2.793600805521 0.00552954699776965 -113.568664040809 96.991102327541 -1.17091837617522 0.242511015832419 PPIE essential 1 1 1 2.793600805521 -1.17091837617522 7.93623716801860e-09 293.572904500505 54.0342859701518 5.43308566458476 1.10786883753891e-07 -302.5803704677 137.838780517829 -2.19517591008114 0.0288779728446032 ZMPSTE24 other 9.25444616162648e-05 1 0.00137708096506087 5.43308566458476 -2.19517591008114 4.52558328515515e-08 802.553843752784 144.188393541533 5.56600863662173 5.7137962059802e-08 -643.330657867353 479.086127481514 -1.34282881712574 0.180325871956592 STARD7 other 0.000508223002922923 1 0.000718281321053771 5.56600863662173 -1.34282881712574 1.91204623179513e-07 100.88919518312 22.413764241868 4.50121604271465 9.50206489478012e-06 -71.1104351911347 47.3618489755819 -1.50142861246394 0.134240135902261 NOA1 other 0.00207724702622223 1 0.106888728001382 4.50121604271465 -1.50142861246394 0.00147302847740896 116.258606752753 40.8723066668 2.84443468533643 0.00473828054450616 -87.8773101609071 86.3660380624808 -1.01749845347002 0.309692299762915 REST other 1 1 1 2.84443468533643 -1.01749845347002 0.949793227419853 3.25688889767747 61.1137902128569 0.0532922092760711 0.957532341037304 -45.0494871167045 148.734710155435 -0.302884828091745 0.762174433021481 HAL other 1 1 1 0.0532922092760711 -0.302884828091745 0.00227147990796328 178.102577758841 65.5346956646481 2.71768375442257 0.00693209092496778 -333.578291435876 183.790885894224 -1.81498821235269 0.0704618022035548 SSH1 other 1 1 1 2.71768375442257 -1.81498821235269 5.38115130373748e-09 6983.22511788718 1327.10541653446 5.26199729944803 2.67491358144733e-07 -15378.0922245727 6725.1584782228 -2.28665127734455 0.022894548771964 GSTP1 other 6.3276958180649e-05 1 0.00327436171504968 5.26199729944803 -2.28665127734455 9.6566621718457e-26 5031.34599121305 614.198080137742 8.1917318759523 6.46046309060893e-15 -1541.3172608857 1121.65096450438 -1.37415052423795 0.170368801403987 APLP2 other 1.44396069455609e-21 1 9.30048266524061e-11 8.1917318759523 -1.37415052423795 5.04817500621676e-09 94.5771417619627 15.444277138634 6.12376616354398 2.67633237201952e-09 -22.1595164993742 59.7398959004714 -0.370933296172674 0.710932654223122 FAM234B other 5.94271161731837e-05 1 3.52178576834048e-05 6.12376616354398 -0.370933296172674 1.70798850914722e-05 32.6685295402501 7.060227457332 4.62712139767169 5.45616460025658e-06 -9.54396604255525 28.8275837653545 -0.331070620425197 0.740814817136448 SLCO1A2 other 0.159679845720174 1 0.0623366805579315 4.62712139767169 -0.331070620425197 6.15057679785509e-26 635.294467787113 56.9446591582829 11.1563485878676 1.23635975254279e-24 -318.332028265851 223.06632089108 -1.42707346852817 0.154533734804992 WBP11 essential 9.19941771655186e-22 1 1.86171051537894e-20 11.1563485878676 -1.42707346852817 1.05430816963864e-08 771.970840285155 160.517058061347 4.8092760333928 2.33896820452596e-06 -996.565324965876 357.724247984193 -2.78584784392338 0.00565819791720387 EIF3I essential 0.000122173230697726 1 0.027305114819636 4.8092760333928 -2.78584784392338 0.767156314530671 3.36098055577842 5.51551468189538 0.609368436061062 0.542714008151351 6.02004133478782 11.2900153647532 0.53321817024112 0.594253852699703 NKAIN1 other 1 1 1 0.609368436061062 0.53321817024112 0.000676192281696665 838.127413127408 262.240638502338 3.19602414756909 0.00153327429752263 -776.795366795369 560.822890963353 -1.3850992520313 0.166992990979081 COL16A1 other 1 1 1 3.19602414756909 -1.3850992520313 0.000228359032044851 13.6625587744579 104.771168530665 0.130403802554318 0.896329151744071 -936.438656529656 233.490371214835 -4.01060930974338 7.54858983813794e-05 TXLNA other 1 1 1 0.130403802554318 -4.01060930974338 0.000471146671587385 186.977872063632 47.3446131582201 3.94929559227305 9.65049739741322e-05 51.8016640386415 159.148783679515 0.325492051154828 0.74502208669206 NCOA1 other 1 1 1 3.94929559227305 0.325492051154828 4.80324909383954e-09 224.757860889199 36.1219704563738 6.2221927001643 1.53420190063276e-09 -65.7971560459033 125.673042853768 -0.523558231358049 0.600948219976761 AGBL5 other 5.66014873218051e-05 1 2.03128331643777e-05 6.2221927001643 -0.523558231358049 0.00211291010641194 43.4480667452303 12.3660238976449 3.5135033786814 0.000505926283353753 42.382289831933 41.5894606579041 1.01906322326587 0.308942775236435 EFR3B other 1 1 1 3.5135033786814 1.01906322326587 2.16319701153196e-08 200.767618523814 33.1647782255388 6.05363971254334 3.97439063994554e-09 14.8034539654604 113.591105180372 0.130322298933124 0.896393579770263 KIF3C other 0.000247210154477872 1 5.20128503049673e-05 6.05363971254334 0.130322298933124 6.14421267034791e-08 1298.13105488945 239.365702277963 5.42321244244923 1.15824646593455e-07 -1221.19594104059 819.840086947785 -1.48955382943889 0.137329589050174 RAB10 other 0.000685325481250605 1 0.00143819463675094 5.42321244244923 -1.48955382943889 3.61447186748872e-09 747.37922522171 120.775961019776 6.18814554577903 1.8612214374491e-09 -312.824417042669 413.753564889272 -0.756064584304877 0.450166683804118 HADHA other 4.27989613829339e-05 1 2.45923188530149e-05 6.18814554577903 -0.756064584304877 0.0724860639703968 9.35309619424633 28.5985090392746 0.327048384984044 0.743845116895733 -219.792371343232 99.4979400801892 -2.20901428879928 0.027881812320689 MAPRE3 other 1 1 1 0.327048384984044 -2.20901428879928 3.15418577648616e-11 607.507876120929 87.5826795776556 6.93639289241293 2.234809232759e-11 -312.671262798944 305.687755025596 -1.02284523229517 0.307153644326481 CAD other 4.00766001245776e-07 1 3.07196877135053e-07 6.93639289241293 -1.02284523229517 4.39377428173889e-11 2225.70506004276 482.719097547816 4.61076653347507 5.81983308853455e-06 -3850.88213286412 1203.85401075501 -3.19879495226252 0.00151907444252955 CD59 other 5.56207886325326e-07 1 0.0663577368754709 4.61076653347507 -3.19879495226252 7.9913198179867e-08 397.476308838092 221.583953047241 1.79379554959627 0.073829793135413 -2189.61809479845 528.04741119359 -4.14663162508281 4.37074609992118e-05 CD82 other 0.000886317281012904 0.631878763665605 1 1.79379554959627 -4.14663162508281 5.3313835187074e-11 71.1414051308888 14.0866173689247 5.05028306425273 7.4354866767774e-07 -51.7972460737163 19.2261076179113 -2.69410985848541 0.00743120588651712 AK6 essential 6.73193796907184e-07 1 0.00891217433078539 5.05028306425273 -2.69410985848541 0.111718222758358 -12.5031580190071 6.21822309629109 -2.01072843887906 0.0451926698887275 4.86728539154606 13.0046230295185 0.374273470326518 0.708448750315656 FCN1 other 1 1 1 -2.01072843887906 0.374273470326518 2.03771627967931e-23 138.75247677138 12.473636249194 11.1236590517337 1.77800354393709e-24 -52.3487214122326 89.2120583515942 -0.586789749945245 0.557763887363026 MYNN other 3.01846912508896e-19 1 2.67607313397971e-20 11.1236590517337 -0.586789749945245 0.518572391426327 32.9760406242667 29.9634136925017 1.10054351492397 0.271938350633474 64.7660980323847 212.343184269733 0.305006719453327 0.760563105686156 MECOM og 1 1 1 1.10054351492397 0.305006719453327 5.73747620764731e-05 222.635349667251 62.4640668695038 3.56421476898658 0.000420559642738574 -92.6688013533097 85.8421436749907 -1.07952571296641 0.281166423787231 SCAMP1 other 0.508168267711322 1 1 3.56421476898658 -1.07952571296641 1.72965548830717e-15 253.320079836514 39.9947689203736 6.33383031518083 8.12625095075578e-10 -368.693927554187 90.6897663406448 -4.06544136600061 6.04418365961606e-05 PREP other 2.3959187824031e-11 0.869153610252789 1.08428566435934e-05 6.33383031518083 -4.06544136600061 0.0106728753150469 0.684449879821635 10.2211535096595 0.0669640544166364 0.946652269085726 -67.3613608208126 23.1768815908994 -2.90640311366403 0.00391194045321035 HACE1 other 1 1 1 0.0669640544166364 -2.90640311366403 2.31065167169529e-54 600.089224630721 30.9138922522505 19.4116360286866 3.22828555238261e-55 242.225041827453 129.844683520527 1.86549834201844 0.0630715310381642 SEH1L essential 3.54407753404624e-50 1 4.9528356944654e-51 19.4116360286866 1.86549834201844 0.00731235228692061 85.6718792473342 46.5900717296168 1.83884411564178 0.0668645957750673 -138.38254704159 89.0160590422169 -1.5545795728382 0.121034652924637 WDR47 other 1 1 1 1.83884411564178 -1.5545795728382 1.53829013977133e-05 39.3713169236996 67.6647528784071 0.58185857848989 0.561072902265877 -465.634414081301 118.098381087661 -3.94276712172434 9.90445996226924e-05 WDFY1 other 0.144414678321733 1 1 0.58185857848989 -3.94276712172434 0.0379851204517309 -4.54814157100961 3.57862109375341 -1.27092012589668 0.204680176361616 -16.8388514893187 6.55816523750839 -2.56761622793698 0.0106938878901901 OVGP1 other 1 1 1 -1.27092012589668 -2.56761622793698 1.92614361436891e-09 178.85216190049 47.9329448718169 3.73129926356037 0.000225340417128001 -305.667001204335 91.7103005337498 -3.3329625944454 0.000959996968817261 SLC25A24 other 2.3025120766166e-05 1 1 3.73129926356037 -3.3329625944454 2.83471967678615e-08 206.091011892188 44.5371640564681 4.62739413831757 5.38674037054762e-06 -267.784186414492 97.8540729912129 -2.73656658561916 0.00655518746970072 MAP3K4 other 0.000321910766495835 1 0.0615758291757299 4.62739413831757 -2.73656658561916 0.0829463861532092 14.4213650119363 8.24381959299934 1.74935475591714 0.0811883739903978 -35.0777789100157 35.6823775682869 -0.983056099411699 0.326322494993783 PILRA other 1 1 1 1.74935475591714 -0.983056099411699 0.0558820512288375 237.113915235932 101.200575572545 2.34300955201543 0.0197410393241276 -226.190311907026 354.238520766772 -0.638525452899426 0.523588407919931 IGSF9 other 1 1 1 2.34300955201543 -0.638525452899426 0.347904266261507 -6.32699077110528 4.35342179016704 -1.45333741504117 0.147135156783455 -5.11027720372808 16.8233415753102 -0.303761127410494 0.761512355587213 ABCB1 other 1 1 1 -1.45333741504117 -0.303761127410494 1.03761796508921e-10 86.0103460079528 16.6144318857382 5.1768454437364 3.99539195182058e-07 -152.241093918811 47.7471435234692 -3.18848590060639 0.00157161679259648 ZNF213 other 1.29629612378595e-06 1 0.00485120490790054 5.1768454437364 -3.18848590060639 0.00031003275069739 418.979465780707 125.152057920981 3.34776329483326 0.000912772306964868 -118.055050198041 275.290211516295 -0.428838532063292 0.668332005883054 AKR1B1 other 1 1 1 3.34776329483326 -0.428838532063292 3.31322677569853e-05 391.437001705149 84.8799002969857 4.61165718074071 5.79002716225434e-06 87.9381747797342 426.933191120427 0.205976430525236 0.836940712573552 CPNE3 other 0.30123857844651 1 0.0660352597855108 4.61165718074071 0.205976430525236 3.95206939146803e-08 137.348653313382 27.2305005156006 5.04392687290834 7.65616164206677e-07 -145.509777922636 85.2182272789112 -1.7074959497385 0.0886998344541571 RRN3 essential 0.000445319179030618 1 0.00917055041486757 5.04392687290834 -1.7074959497385 3.0902067906965e-76 2592.778598803 95.5727350108091 27.1288521617568 2.57930821782619e-76 -734.210715898937 1408.86493650992 -0.521136339525735 0.602734953498031 CTTN other 4.74593958915169e-72 1 3.96130156093746e-72 27.1288521617568 -0.521136339525735 6.52232764493349e-06 106.441056633944 22.3110124560504 4.77078558597993 2.81155806033586e-06 71.9140366735567 68.9936484197072 1.04232836385292 0.298058763833244 WNT11 other 0.0632861451387896 1 0.0326843624514043 4.77078558597993 1.04232836385292 9.01880467989266e-12 162.526189935318 22.8262891648536 7.12013191288072 7.14484961177116e-12 -100.286771910108 90.3876532851762 -1.10951848250446 0.268039673335631 MTIF2 other 1.16135147862978e-07 1 9.90633398672071e-08 7.12013191288072 -1.10951848250446 9.32032843148879e-18 99.2392649069561 27.6499429084042 3.58913091559377 0.000390261810635857 -357.983148451098 64.3664732200254 -5.56163994300877 6.13627868150162e-08 DDHD2 other 1.32590992266359e-13 0.000928787141232085 1 3.58913091559377 -5.56163994300877 0.0671733615804341 2.68626439682602 24.7693366948727 0.108451204403147 0.913705968319034 -135.825987511822 60.5711532566699 -2.24242036363845 0.0256208740316124 TTC39A other 1 1 1 0.108451204403147 -2.24242036363845 1.42171448612107e-05 151.560349267493 37.9348156017567 3.9952836691916 8.02890461555845e-05 -155.355418173719 92.7661308771809 -1.67469977140045 0.0949731660893524 EPS15 other 0.133939721737466 1 0.840305157064347 3.9952836691916 -1.67469977140045 0.0648758622153005 -9.75994933419836 21.3551685165874 -0.457029843928294 0.647960662858526 -121.965590708116 51.9548609558626 -2.34752992240187 0.0195091540189239 ORC1 other 1 1 1 -0.457029843928294 -2.34752992240187 0.000252372731824908 24.788536941094 47.1961440172881 0.525223775315498 0.599797123066651 -301.02130423651 83.4067174236422 -3.60907746443913 0.000357313188533248 MGST2 other 1 1 1 0.525223775315498 -3.60907746443913 2.16674963300693e-12 329.372374055555 55.3969171505746 5.94568057208466 7.263594519031e-09 -410.630058516244 136.98098548257 -2.99771575645799 0.00293514401028245 CHERP essential 2.83280847019326e-08 1 9.42669296679844e-05 5.94568057208466 -2.99771575645799 6.50983965447297e-08 74.7449734186377 24.9810873108566 2.99206245462959 0.00298642497321578 -137.174006025577 43.0889171652293 -3.18351017036627 0.00159802542483809 ATG16L1 other 0.000725131039111744 1 1 2.99206245462959 -3.18351017036627 9.70149250497977e-11 124.180103591938 42.2375682003575 2.94003913773821 0.00352064398004244 -319.513843035695 72.5991974863371 -4.40106577067641 1.46960290572113e-05 USP40 other 1.21375372729802e-06 0.215473178036832 1 2.94003913773821 -4.40106577067641 0.0131801403105549 136.340824466847 62.2362162815916 2.19069912364152 0.0291945750529594 -247.237784728235 157.93857482758 -1.56540468342292 0.118476384723481 POMGNT1 other 1 1 1 2.19069912364152 -1.56540468342292 0.10817264636096 7.99656278216837 21.4976710038089 0.371973446832988 0.710158819179512 -108.121971199047 54.5552368590577 -1.98188070337551 0.0483479030556743 RAD54L other 1 1 1 0.371973446832988 -1.98188070337551 3.89004831071159e-05 189.394580475588 46.2868750202863 4.09175560874615 5.42797635571158e-05 -150.181664908954 117.432646643546 -1.2788749057561 0.201870662633072 MAST2 other 0.351388063906578 1 0.576939606848584 4.09175560874615 -1.2788749057561 4.97007067990074e-30 1422.55023445621 128.302828203372 11.0874425324541 2.76663441522334e-24 -1023.97666322409 326.912533309557 -3.13226492988104 0.00190022435025626 DNAJA1 other 7.51226183266997e-26 1 4.16240147770351e-20 11.0874425324541 -3.13226492988104 2.54688508603289e-22 1597.20433508205 174.896819591022 9.13226632031932 8.90733189899303e-18 -1271.02085768161 446.942099796294 -2.84381547019382 0.00475390650290696 B4GALT1 other 3.75079766620063e-18 1 1.30670558958228e-13 9.13226632031932 -2.84381547019382 8.66379377373352e-28 539.19674775498 48.054241258283 11.220586021885 9.50787182818851e-25 -205.784610645408 122.800766430845 -1.67575998608523 0.094793466101526 CHMP5 other 1.30294794563178e-23 1 1.43188549732519e-20 11.220586021885 -1.67575998608523 6.88401161045843e-33 298.308122434863 26.8555592119814 11.1078723060727 2.23240924296102e-24 -326.792048854788 74.9037201494514 -4.36282801712328 1.74714090678475e-05 NFX1 other 1.04437340142265e-28 0.255659128889812 3.35977591065633e-20 11.1078723060727 -4.36282801712328 1.86324413507312e-12 112.73945180654 26.2051063822215 4.30219401372194 2.25148859935394e-05 -151.482952749326 37.8701485776124 -4.00006227699032 7.87611024138898e-05 DIMT1 essential 2.43842759957019e-08 1 0.246525625650305 4.30219401372194 -4.00006227699032 1.13272262326166e-22 755.204197187069 71.9769995983448 10.492298948294 2.5391274535275e-22 -458.979761424271 345.657279252456 -1.32784636393857 0.185178213465885 EIF2AK1 other 1.67189859193421e-18 1 3.80158162342137e-18 10.492298948294 -1.32784636393857 0.398802247005915 17.5192421096096 14.6804086052175 1.19337564646417 0.233606286364044 -26.0286690686589 59.943481997946 -0.434220172087281 0.664421193401307 EPDR1 other 1 1 1 1.19337564646417 -0.434220172087281 0.00112820003912578 69.4492114507809 19.1558250873038 3.62548786775104 0.000335907935121484 -8.18197896342959 79.2083895754406 -0.103296873062124 0.917792674432422 SNX10 other 1 1 1 3.62548786775104 -0.103296873062124 9.68776825999722e-16 202.638472399651 37.566552150199 5.39411952391744 1.34936973144805e-07 -248.687584885363 76.7585687822949 -3.23986740282637 0.00132277925479407 SEPHS1 other 1.34640603277441e-11 1 0.00167173416029099 5.39411952391744 -3.23986740282637 0.00343980582363819 337.837479598397 120.610562428046 2.80106047760074 0.00540840127741987 -319.091055837133 325.377345565675 -0.980680001806478 0.327503159009731 MRPL28 essential 1 1 1 2.80106047760074 -0.980680001806478 3.21708008908406e-07 489.666196646076 121.784020909895 4.02077541033373 7.24030262484231e-05 -942.177785539179 355.665054281437 -2.64905920387004 0.008472108144884 ITPKC other 0.00345096181156047 1 0.761679836133411 4.02077541033373 -2.64905920387004 0.771141837849748 75.0444367220407 418.331335555525 0.179389948454101 0.857746130252319 -697.679617847379 1112.20844674451 -0.627292141045612 0.530919307112844 CEACAM6 other 1 1 1 0.179389948454101 -0.627292141045612 1.01466123204701e-05 2039.8103860635 638.845581340543 3.19296312855948 0.00154865044592275 -2148.77723852448 916.931662796187 -2.34344316562456 0.0197204333586774 FAT2 other 0.0968088281496055 1 1 3.19296312855948 -2.34344316562456 3.9317428767898e-19 192.099245031814 32.7558580791384 5.86457679013324 1.12227809773069e-08 -260.953522890634 47.4234502247459 -5.50262626725684 7.67676937325931e-08 RBM22 essential 5.6656414854541e-15 0.0011611881353992 0.000144751429045304 5.86457679013324 -5.50262626725684 3.09843294748452e-05 921.255943510793 221.435323873234 4.16038384209281 4.08980154333847e-05 -787.725702644739 576.190914662158 -1.36712621216288 0.17254832974192 TMED2 essential 0.282732006457963 1 0.439612767893452 4.16038384209281 -1.36712621216288 0.751473389487323 -19.2774568170168 27.9399790735155 -0.689959601125472 0.490719658054805 -25.3186478681665 89.7257319371178 -0.282178226040112 0.77798926605377 ERO1B other 1 1 1 -0.689959601125472 -0.282178226040112 0.000569922171531807 108.408123496234 42.3272035732271 2.56119266912319 0.010890969103134 -153.254673154001 83.3070859087736 -1.839635506178 0.0667508201617764 ZFAND6 other 1 1 1 2.56119266912319 -1.839635506178 0.464440873200819 -13.8825514114288 21.6588034015439 -0.640965761314366 0.522003690460958 -68.455690243915 55.2989501046019 -1.23792025191122 0.216653101993837 HSD17B2 other 1 1 1 -0.640965761314366 -1.23792025191122 0.00683376531279081 -16.0427275680573 9.26839801956035 -1.73090619697171 0.0844415529178948 -96.9069677008546 31.9789658446686 -3.03033463219419 0.00264395478910902 LAT2 other 1 1 1 -1.73090619697171 -3.03033463219419 4.72372140889486e-24 103.05667309366 19.252748559857 5.35282911804802 1.65814894931611e-07 -146.461762399785 35.2839111492957 -4.15095032350768 4.25302996225927e-05 ZW10 essential 7.01094731508175e-20 0.614945602243068 0.00204615580345608 5.35282911804802 -4.15095032350768 3.96202802453371e-24 74.9630422673409 14.4353310189952 5.19302551279901 3.70711473006702e-07 -115.294585630841 26.5239173006785 -4.34681590670966 1.86312371946432e-05 ALG9 other 5.88400781923501e-20 0.272388687785684 0.00450748080028849 5.19302551279901 -4.34681590670966 0.14091053194654 537.042895141046 309.695659956834 1.73409887376497 0.0838635973251373 -416.27692372532 736.299298404423 -0.565363738125788 0.57222255233897 MYBPC2 other 1 1 1 1.73409887376497 -0.565363738125788 0.000336462796539864 35.9360078297233 8.96739061829996 4.00740966456707 7.65167296277554e-05 62.2700933239745 22.318473368473 2.79006956685205 0.00558771374310784 NOX4 other 1 1 0.802813527254409 4.00740966456707 2.79006956685205 9.69599892079441e-16 54.0680203086197 22.93545052529 2.35739953087039 0.01900518697984 -238.339393195675 42.5341929959818 -5.6034774944053 4.53509241599573e-08 ACOX3 other 1.3474529700228e-11 0.000686794395478393 1 2.35739953087039 -5.6034774944053 6.95073584040649e-23 202.459576114961 30.9443189159604 6.54270584092697 2.44439177453572e-10 -235.183653398079 72.1181762548271 -3.26108708804651 0.00123143888219243 MTMR2 other 1.02724924985367e-18 1 3.29552899042906e-06 6.54270584092697 -3.26108708804651 0.0415663118884222 549.617324218748 268.946949269391 2.04359010470955 0.041812635708365 -618.879717261907 616.19260619127 -1.00436082978542 0.315963576505382 PPP1R15A other 1 1 1 2.04359010470955 -1.00436082978542 0.117984157524964 14.8287890624999 8.2447078757736 1.79858271341222 0.0730269775444324 -11.4293750000001 18.8897031442804 -0.605058476181547 0.545568966790133 HSD17B14 other 1 1 1 1.79858271341222 -0.605058476181547 0.133192164543498 26.7499940494241 15.3188818830896 1.7462106081615 0.0817339531866368 91.3740257872093 67.1459826695492 1.3608263987571 0.174526178471553 ACHE other 1 1 1 1.7462106081615 1.3608263987571 0.000501268102669952 11560.0784960937 2989.1432131224 3.86735518236288 0.000133288847421533 723.817127976186 6848.51771613854 0.10568960437534 0.915894848698346 FTL other 1 1 1 3.86735518236288 0.10568960437534 0.041478898576383 130.929320609795 53.9232860998479 2.42806642694879 0.0157305161888832 -43.2670975573666 236.357461437341 -0.183057887380622 0.854868524727867 SRRT essential 1 1 1 2.42806642694879 -0.183057887380622 0.0166432173799957 123.81712890625 68.5110832359817 1.80725691461876 0.0716612688115102 -279.709032738096 156.967844576221 -1.78195116008154 0.0757053667787429 BAX og 1 1 1 1.80725691461876 -1.78195116008154 0.000130637045200959 37.7537009804698 13.1788435381883 2.86472032777921 0.00446158936371663 -87.873885576896 32.0112997287503 -2.74508958778621 0.00640587625558509 NLK other 1 1 1 2.86472032777921 -2.74508958778621 4.50221696640997e-18 391.0071942703 43.0521233871844 9.0821814002952 1.26512985557508e-17 -241.110240887686 137.887520272075 -1.74860089159581 0.0813466652001341 PIGS other 6.42241250258382e-14 1 1.85417431633083e-13 9.0821814002952 -1.74860089159581 0.251924239338438 -89.4847612217028 207.895792724247 -0.430430842534631 0.667172012361618 436.70585622382 319.574932809455 1.36652099832938 0.172734885137317 ADAMTS2 other 1 1 1 -0.430430842534631 1.36652099832938 0.240202793274538 25.8851899668016 214.448325200367 0.120705955351324 0.904001887025019 -715.954629288086 465.644194304121 -1.53755729813842 0.125173647364789 TMPRSS11E other 1 1 1 0.120705955351324 -1.53755729813842 4.41863758754423e-11 310.516274586149 47.029653477059 6.60256352383329 1.68104806383934e-10 -258.332083033849 113.380408568548 -2.27845433170816 0.0233582334452129 ATXN7L3 other 5.59311145831349e-07 1 2.27412182076187e-06 6.60256352383329 -2.27845433170816 7.92048689231326e-07 93.4284753848859 19.9804490698159 4.67599477161036 4.31972282072314e-06 -82.73761830765 47.0960215943685 -1.75678572216264 0.0799107357190415 PGS1 essential 0.0082602757799935 1 0.0496422546557503 4.67599477161036 -1.75678572216264 1.50138363856519e-05 541.430780865949 123.461005389144 4.38543959009068 1.57415629887641e-05 -401.310332766118 284.70059298869 -1.40958727396139 0.159635736099666 PSMC5 essential 0.141130062025128 1 0.17424336072263 4.38543959009068 -1.40958727396139 1.4468221049142e-14 105.081000790949 19.2470288320911 5.45959595674029 9.58823732041172e-08 -120.669985924469 29.3071386586701 -4.11742638303484 4.88120851942606e-05 UIMC1 other 1.97462280878689e-10 0.704504825608763 0.00119498201724291 5.45959595674029 -4.11742638303484 0.816180476238564 0.205664218525847 2.40613935635053 0.0854747743446516 0.931937569685491 3.87694328148462 6.4180099092165 0.604072498535284 0.546224790289623 CETP other 1 1 1 0.0854747743446516 0.604072498535284 0.000578114499316106 2674.40615791753 713.097835553456 3.75040565905217 0.000209733570497331 1462.07327748413 1879.77592313722 0.777791256653626 0.437270356918929 MMP2 other 1 1 1 3.75040565905217 0.777791256653626 7.30115663158413e-08 221.664129311299 51.5180538192621 4.30264951562323 2.24906848693008e-05 -210.04817577183 135.8052042062 -1.54668723484928 0.122933259878166 LPCAT2 other 0.000810939467070049 1 0.246340471373452 4.30264951562323 -1.54668723484928 0.0250832497428609 34.5548823358277 13.5494045572004 2.5502878882943 0.0112304290697118 11.6352602592491 35.7190214686471 0.325744093226691 0.744831548995492 GNAO1 other 1 1 1 2.5502878882943 0.325744093226691 1.59784993407459e-20 220.227892402094 32.80023470271 6.7142169682066 8.66552166289884e-11 -334.64839082394 86.5334561319993 -3.86727175571796 0.000133410241815217 OGFOD1 other 2.32726842897963e-16 1 1.1786842565875e-06 6.7142169682066 -3.86727175571796 9.58682001315845e-15 83.0643134021596 55.7062093114556 1.49111408636233 0.136916623897654 -626.902746430906 103.028159464678 -6.08477089844385 3.33034807252816e-09 SH3BP2 other 1.31358607820297e-10 5.0734522536894e-05 1 1.49111408636233 -6.08477089844385 4.73785606095226e-22 377.137220213717 51.3989317562146 7.3374524980885 1.8061348696475e-12 -228.827622188544 95.0618863273541 -2.4071437147855 0.016643771225221 NOP14 essential 6.96559598081202e-18 1 2.52714390961079e-08 7.3374524980885 -2.4071437147855 2.49314980080902e-31 910.207004036458 110.420206286724 8.24311993832864 4.37759183281804e-15 -834.669448588328 204.221230667939 -4.0870846084827 5.52885217166069e-05 ADD1 other 3.77462879842486e-27 0.796320578284289 6.31161190455705e-11 8.24311993832864 -4.0870846084827 4.37731950858208e-07 54.4325543105419 10.8896099179159 4.99857705839285 9.57227505192365e-07 -39.6433128613897 33.483519149856 -1.18396494358808 0.23731395690422 L2HGDH other 0.00464652465835987 1 0.0114235530469657 4.99857705839285 -1.18396494358808 0.0451855198395132 -26.1709136822585 11.7931154672842 -2.21916878155398 0.027185152406076 22.9910400905007 35.9680544163427 0.639207220506606 0.523151209025815 TXNDC16 other 1 1 1 -2.21916878155398 0.639207220506606 0.296608663502609 58.5328775520002 38.1573219021687 1.53398809544528 0.126033141212389 72.5907148281665 116.376765271778 0.623756079305381 0.533237780785318 NID2 other 1 1 1 1.53398809544528 0.623756079305381 0.0226293119184461 67.8002337362169 24.4904467994352 2.76843596572441 0.00596087028196363 6.42430943547056 105.303772941902 0.0610074003617606 0.95139139979319 GMCL1 other 1 1 1 2.76843596572441 0.0610074003617606 5.53903124789502e-30 1500.88642078698 117.24058694737 12.8017648142681 1.57237386202393e-30 -49.4919349573736 636.91636120239 -0.0777055481255675 0.938111304091322 SF3B2 essential 8.37113792494374e-26 1 2.38985103289017e-26 12.8017648142681 -0.0777055481255675 7.28195819766126e-23 233.643043851339 22.2354762854605 10.5076698538774 2.24974430392488e-22 -169.949614484185 124.373759596256 -1.36644268884271 0.172762429202809 KLHL42 other 1.07598214328643e-18 1 3.36876712069711e-18 10.5076698538774 -1.36644268884271 9.85341726229845e-15 3809.58575494181 473.228817732679 8.05019815402238 1.6397409519339e-14 -1522.52368772983 2213.75400299239 -0.687756492217202 0.492104337878454 GNAS other 1.34981963076227e-10 1 2.35138852507322e-10 8.05019815402238 -0.687756492217202 8.56317848210816e-37 596.781621366069 41.1887806006743 14.4889363720639 1.16269931126553e-36 -287.887849685243 243.14600511124 -1.18401225450336 0.237318201265704 DNM1L essential 1.30494276888846e-32 1 1.77509303850908e-32 14.4889363720639 -1.18401225450336 3.19156759105454e-13 2305.675001116 296.472338777508 7.77703245646243 1.03561500260438e-13 -532.050026949319 1658.3130002106 -0.32083812095892 0.748543150809003 PTHLH other 4.24701899341628e-09 1 1.47378371020629e-09 7.77703245646243 -0.32083812095892 0.205753771112485 18.8136560704481 10.5989251171189 1.77505321176967 0.0768425926988546 12.1055394196419 49.7309417477208 0.243420675221714 0.807835988262183 PHACTR3 other 1 1 1 1.77505321176967 0.243420675221714 1.02791576320697e-33 262.85765075329 19.600767625282 13.4105794108922 8.26508265285585e-33 -189.994033039463 107.156098801274 -1.7730585115068 0.0771761709621547 ERGIC2 other 1.56099287800611e-29 1 1.2583588338973e-28 13.4105794108922 -1.7730585115068 0.000521492025851566 136.245125204371 36.7473804586353 3.7076146246053 0.000246648852588403 -79.2010257292832 174.735453870009 -0.453262483229095 0.650667901504951 TFAP2C other 1 1 1 3.7076146246053 -0.453262483229095 2.80918487273253e-05 125.268297048447 29.214564105975 4.28787150799306 2.39314359824251e-05 -111.696344204458 138.916571874239 -0.804053416359687 0.421964899514246 AURKA essential 0.257546069132119 1 0.261594526723888 4.28787150799306 -0.804053416359687 0.0725355724156136 -4.72128388262628 2.05425610024272 -2.29829371423964 0.0221915374816097 -4.14615540831254 9.76808054237227 -0.424459584493313 0.671516793989492 CASS4 other 1 1 1 -2.29829371423964 -0.424459584493313 9.02706757056095e-09 72.6494516761771 12.6089415128052 5.76174071411124 1.97639590990522e-08 22.1034721026612 40.8325702694015 0.5413196366731 0.588668707285833 AAMDC other 0.000105011877048335 1 0.000253117024181561 5.76174071411124 0.5413196366731 0.000384684923872735 46.1917491574471 20.1619725824753 2.29103322943693 0.0226111532946364 -71.9193671001479 36.8246091043646 -1.95302459005936 0.0516880444295979 RFX2 other 1 1 1 2.29103322943693 -1.95302459005936 0.000132146932082662 56.0213270716307 13.414937006332 4.17604100900272 3.84404078026042e-05 -15.0513005741048 30.8911044975289 -0.487237372017851 0.626429013471993 METTL2A other 1 1 0.414272274888665 4.17604100900272 -0.487237372017851 0.769623020247297 132.69306640625 190.423840266348 0.696830114447072 0.486415004205073 151.506919642858 436.285902232486 0.347265219590165 0.728620356331593 SULT2B1 other 1 1 1 0.696830114447072 0.347265219590165 8.8046836455949e-05 -11.2476908248202 13.6549176730547 -0.823709896619536 0.410717892051533 -139.731643822983 31.9424086523046 -4.37448676284784 1.64905705023689e-05 ALG6 other 0.762837791054342 0.241388971013676 1 -0.823709896619536 -4.37448676284784 3.28213147962296e-10 218.726836885649 38.782448206875 5.63984088159952 3.77074209676017e-08 -208.378855953098 94.3167630470536 -2.20935122475673 0.0278648712415766 CNOT3 other 4.0426013434516e-06 1 0.000477262827186934 5.63984088159952 -2.20935122475673 0.130249198932012 27.2307871876179 13.9778359189512 1.94814042356144 0.0522860542598123 37.1833846619153 44.4167030353963 0.83714868778719 0.403143665784857 PTPN4 other 1 1 1 1.94814042356144 0.83714868778719 1.49898576362141e-09 446.456749568529 69.9258443638023 6.38471731918965 6.14677626153414e-10 -144.986353718341 222.200023066188 -0.652503774381486 0.514552118821277 DDX18 essential 1.79848311919296e-05 1 8.22377196030653e-06 6.38471731918965 -0.652503774381486 4.07399409504598e-17 186.273711575237 64.4120348378729 2.89190850815525 0.00409294659492127 -707.225227469154 112.612982987384 -6.2801393650001 1.1098624887283e-09 GNA11 other 5.74962786633839e-13 1.69353917155052e-05 1 2.89190850815525 -6.2801393650001 0.000222778536134011 159.146087777125 45.4954111603667 3.49806900779842 0.000534971330252308 -98.8397408719355 87.8935477765398 -1.12453921103771 0.261627158269614 ASAP3 other 1 1 1 3.49806900779842 -1.12453921103771 1.74653636360569e-06 70.1306331390913 13.8957581693256 5.0469094442002 7.63004623572115e-07 -114.550279104596 123.708022808788 -0.925972919975063 0.355173447372867 EDEM2 other 0.0177273440905977 1 0.00914003238577036 5.0469094442002 -0.925972919975063 0.00103779194272233 46.5352647599746 12.512737422822 3.71903151065081 0.000236694979943478 -0.173788503197598 83.6403176324075 -0.00207780778596974 0.998343465673369 DNMT3B other 1 1 1 3.71903151065081 -0.00207780778596974 0.515177050406222 -3.62169385354449 3.43973034193664 -1.05290051647054 0.293217289400231 -12.7016653716716 21.2721769117708 -0.597102281743588 0.550880640078377 REM1 other 1 1 1 -1.05290051647054 -0.597102281743588 5.28937470313461e-10 642.207238144921 96.647765876278 6.64482238489643 1.38332259054358e-10 -275.300130132788 597.650453057983 -0.460637365410111 0.64538492293675 TPX2 essential 6.46678951205238e-06 1 1.87440211018655e-06 6.64482238489643 -0.460637365410111 0.671400024365667 1.72932281907141 5.00244546461995 0.345695486597933 0.72980380425081 -21.6589861116214 28.6697115522181 -0.755465783887377 0.450537675121623 FER1L4 other 1 1 1 0.345695486597933 -0.755465783887377 8.34506390572879e-09 100.163087322266 16.574376819347 6.04324907138275 4.35675000490753e-09 -100.283283562584 102.574672850992 -0.977661256675555 0.329009154944311 PDRG1 essential 9.72533747573633e-05 1 5.69383658141365e-05 6.04324907138275 -0.977661256675555 0.11498337970946 193.524903495273 93.17402661726 2.0770262971486 0.0386092984123059 304.979286255562 509.151000677115 0.598995751456784 0.549606244785642 EPB41L1 other 1 1 1 2.0770262971486 0.598995751456784 1.93449090546917e-06 82.2178057122804 15.7410588843514 5.22314326604897 3.20973469048203e-07 60.4296935689685 36.6230002873233 1.65004759563311 0.0999331037105932 SLC15A1 other 0.0195654410179152 1 0.00391170366729045 5.22314326604897 1.65004759563311 1.53342079778008e-14 591.926291808706 79.1402903368542 7.47945565134042 7.48154291838776e-13 -351.825850437024 183.94194328367 -1.9127005192853 0.0566930256024364 DOCK9 other 2.09127928401248e-10 1 1.05160567260858e-08 7.47945565134042 -1.9127005192853 0.00389644038980923 96.8129993228153 37.9960612662216 2.5479746083282 0.0113081289025268 -143.919480735024 93.0314501465026 -1.5469981442661 0.122864565864359 ANKRD10 other 1 1 1 2.5479746083282 -1.5469981442661 3.20070733318068e-10 44.7407589668602 6.59556508453511 6.78346106715946 5.89594565374329e-11 10.2759359502916 15.3614756871027 0.668941979247421 0.504027144670144 TGDS other 3.94359150521191e-06 1 8.0408906825751e-07 6.78346106715946 0.668941979247421 0.024898248808666 -0.0186946642637535 11.1895247389529 -0.00167072907025923 0.998667995989398 -36.7123442764237 15.8783080409935 -2.31210681778199 0.021408262168905 DOCK3 other 1 1 1 -0.00167072907025923 -2.31210681778199 0.0655589738423961 14.1629397477083 7.63543761273727 1.85489561516186 0.0645336398462495 -2.40385097547597 10.8349401132988 -0.221861030180082 0.824564029997058 C3orf18 other 1 1 1 1.85489561516186 -0.221861030180082 2.12307617583562e-11 172.980284572827 37.6501116954832 4.59441623897172 6.25062040490386e-06 -298.267241612873 99.7222223255318 -2.99098069274082 0.00299673182198156 COQ9 other 2.70862058513109e-07 1 0.0711767992382595 4.59441623897172 -2.99098069274082 0.00258029104186791 131.01812676902 107.543242853694 1.21828320675863 0.224016628089696 -399.717888326615 173.092519048816 -2.30927304382165 0.0215669506439297 TMEM40 other 1 1 1 1.21828320675863 -2.30927304382165 3.73852122979956e-07 13.8538306186812 9.14283187318974 1.51526691191882 0.130691953318308 -49.1984619116858 13.1484801915384 -3.74176035518896 0.000216540713353116 KIF9 other 0.00399161911705699 1 1 1.51526691191882 -3.74176035518896 0.739939102008555 8.27377318894338 11.2571799629637 0.734977429175354 0.462901802092141 -7.494968044237 50.1798144407999 -0.149362211234943 0.881363713715904 ARHGAP28 other 1 1 1 0.734977429175354 -0.149362211234943 1.64685922674221e-16 155.651209088599 18.6635700227602 8.33984113965242 2.24134605825754e-15 -65.6883224835352 69.8945130336156 -0.939820876238777 0.34801831290009 CRLS1 essential 2.30972006550595e-12 1 3.23964159260545e-11 8.33984113965242 -0.939820876238777 0.000158112599562577 128.711632378187 31.0591110742292 4.14408616108089 4.38568300011452e-05 36.968088666954 91.706395495302 0.403113528421775 0.687137311447227 PPP1R13B other 1 1 0.470408358592284 4.14408616108089 0.403113528421775 7.52217927283737e-09 420.730829717927 73.0786922878614 5.75722986476882 2.00442027595239e-08 -228.984161211211 270.476139339732 -0.846596530733511 0.397852712348878 ATRN other 8.78214430103763e-05 1 0.000256625927930184 5.75722986476882 -0.846596530733511 1.75259444344191e-05 152.328464921768 35.8809727548152 4.24538280950941 2.86289085636953e-05 -117.437654721561 132.574059548809 -0.885826798404138 0.376376044931991 SMOX other 0.163657269128605 1 0.311224864995931 4.24538280950941 -0.885826798404138 0.563114216458992 -12.0686629297911 21.6727853642548 -0.55685795466309 0.578013724251366 -82.961361627643 80.1226413125519 -1.03542968964312 0.301250113202455 SIGLEC1 other 1 1 1 -0.55685795466309 -1.03542968964312 1.08303918107777e-22 514.415137820522 57.00086072222 9.02469070295973 1.71427161349096e-17 -748.494924119536 211.872064573947 -3.53276835067749 0.000471743993992898 NSFL1C other 1.5986741351889e-18 1 2.51020792363482e-13 9.02469070295973 -3.53276835067749 0.0210102604125449 98.688419086687 52.6209176920521 1.87545986301932 0.0616398739332365 -281.683967048555 192.554350093879 -1.46288030839719 0.144481602377228 SLC4A11 other 1 1 1 1.87545986301932 -1.46288030839719 1.26744020104951e-09 115.652403239752 18.9187289699176 6.11311697649715 2.84128326761911e-09 -48.2485375082807 69.2288109212309 -0.696943033777921 0.4863444274071 C20orf194 other 1.52523753794298e-05 1 3.73515098361208e-05 6.11311697649715 -0.696943033777921 2.48233409342267e-15 62.7083868239136 7.83300901078479 8.00565743478327 2.21804151676692e-14 -25.6779673704342 28.6631253407231 -0.895853716759639 0.371004291159165 ZNF343 other 3.43058571711014e-11 1 3.17800988522365e-10 8.00565743478327 -0.895853716759639 0.133484362275292 35.4375488900784 20.8901645494282 1.69637480864403 0.0907874092443555 -43.0511451038807 76.4428336599856 -0.563180916282753 0.573706084723718 EBF4 other 1 1 1 1.69637480864403 -0.563180916282753 0.297044127794658 191.738482058979 129.03917457138 1.4858935877098 0.138291780283223 -19.5309443785301 472.189682089022 -0.0413624971475931 0.967032705234225 CPXM1 other 1 1 1 1.4858935877098 -0.0413624971475931 1.61527526722358e-14 517.416703373262 67.1793988780521 7.70201448679985 1.68973766912034e-13 -257.348249167265 248.357134970597 -1.03620235914596 0.300890134420466 MAVS other 2.20194324427918e-10 1 2.39621698857956e-09 7.70201448679985 -1.03620235914596 0.0176868884552993 74.8993851546334 26.9560296062369 2.77857630551435 0.0057822634355567 13.4554056987587 98.6394952728901 0.136409920402915 0.891583008440474 LZTS3 other 1 1 1 2.77857630551435 0.136409920402915 6.93870111818589e-14 509.611503154881 66.0141158832788 7.71973533745324 1.55840670846003e-13 -81.2310570668848 277.164713398123 -0.293078639307896 0.769655020336879 XRN2 essential 9.35545071765003e-10 1 2.21122327863394e-09 7.71973533745324 -0.293078639307896 5.49726131320881e-05 85.6089106372181 20.6098986341834 4.15377640408323 4.20992649790743e-05 -32.7434565628703 85.6232903890065 -0.382412967477764 0.702411332777431 KIZ other 0.48810183199981 1 0.452104006610279 4.15377640408323 -0.382412967477764 0.0758504727617682 273.242770921927 223.632234537214 1.22183982773046 0.222670322171296 -1064.42890363771 612.982721251081 -1.73647456402237 0.0834453678343295 DYNLL1 essential 1 1 1 1.22183982773046 -1.73647456402237 0.636728127477125 18.56184391941 21.270347928607 0.87266291937076 0.383503213227659 28.467677926999 57.2112677312856 0.497588657897047 0.619116813321148 TESC other 1 1 1 0.87266291937076 0.497588657897047 1.06137166879602e-17 445.59160404594 47.8854295145628 9.30536926499589 2.27411615725242e-18 160.127640530719 194.784707377396 0.822075011363555 0.411652097014324 SNX5 other 1.50916437586106e-13 1 3.34931827640136e-14 9.30536926499589 0.822075011363555 0.00297513568368576 813.786221041446 242.802707067631 3.35163569990499 0.000899593350183859 827.731960680128 650.066335073185 1.27330383996418 0.203834425294853 RPL6 essential 1 1 1 3.35163569990499 1.27330383996418 0.0105858898680815 -18.2323286846715 6.40444079410627 -2.84682601819817 0.00470098769340519 -42.3424914981853 23.5954391523181 -1.79452017081977 0.0736739224233687 SIRPG other 1 1 1 -2.84682601819817 -1.79452017081977 0.000246915161078795 84.2493581296495 20.512065140734 4.10730745790888 5.08871382508069e-05 56.628825717322 54.9178515011582 1.03115515573525 0.303246779701593 MAPKAPK5 other 1 1 0.542456893753602 4.10730745790888 1.03115515573525 0.288505387358064 10.356708212682 12.0181398565489 0.861756339691656 0.389466906679785 -37.3905547614993 31.6320070706699 -1.18204812859216 0.238064221260728 P2RX7 other 1 1 1 0.861756339691656 -1.18204812859216 9.27011051535083e-14 128.026438452286 16.0766600889701 7.96349725277345 3.09607648796064e-14 33.3100281584893 62.7654590717417 0.530706357463513 0.595997420171201 ESF1 essential 1.24701526652499e-09 1 4.43048545427168e-10 7.96349725277345 0.530706357463513 7.95041362552276e-08 121.817734104225 22.6764406543523 5.37199536563266 1.51025872516569e-07 -97.4549854492964 94.5818727198141 -1.03037699135006 0.303618573006716 RBBP9 other 0.00088193938347924 1 0.00186803901715744 5.37199536563266 -1.03037699135006 0.000573609149541834 304.940954299384 78.9977540293169 3.86012182303584 0.000137114600011705 -8.09391917411547 207.923817150515 -0.038927330620601 0.968972600473245 ANAPC5 essential 1 1 1 3.86012182303584 -0.038927330620601 4.37816009483134e-08 142.229084874872 26.048733351531 5.46011519851932 9.56262398816884e-08 -76.0131619282868 97.6082967418231 -0.778757180133405 0.436698247285419 SLC23A2 other 0.000491930068255249 1 0.00119198108012525 5.46011519851932 -0.778757180133405 0.0250126211348595 78.3455705728594 36.3774233451564 2.15368663771209 0.0320113305425481 -132.375525307001 96.9356308961488 -1.36560234955112 0.173022917202507 SLC8B1 other 1 1 1 2.15368663771209 -1.36560234955112 2.98663229047852e-17 374.443200013775 42.7868270517703 8.75136638575031 1.23196328307867e-16 -83.6164484285129 161.826442228732 -0.516704484612757 0.60571937177493 TMEM230 other 4.22160474259139e-13 1 1.79558648508716e-12 8.75136638575031 -0.516704484612757 0.0946410527267401 6.47217612140767 3.51570887374607 1.84093062134335 0.0665660948763599 -10.2681487542488 14.6637796594745 -0.700238887428614 0.484291718913364 DZANK1 other 1 1 1 1.84093062134335 -0.700238887428614 0.268071105496543 9.29340010622473 5.8061406105942 1.60061574968878 0.110448789417624 7.81900663289512 15.4717363519546 0.505373569910096 0.613644378502278 LHX5 other 1 1 1 1.60061574968878 0.505373569910096 3.02290469080098e-14 45.9432325080193 6.14075927779777 7.48168596579406 7.42329147115909e-13 -35.1851209949334 23.9743561776535 -1.46761484371912 0.143209794063171 TASP1 other 4.09996563213337e-10 1 1.04349208210083e-08 7.48168596579406 -1.46761484371912 0.0665782061199381 -35.4978251996232 203.528127567642 -0.174412380361656 0.861651676801209 -1270.31345399968 544.955597157799 -2.33104029140166 0.0203720284964733 OAS1 other 1 1 1 -0.174412380361656 -2.33104029140166 4.43495035632098e-05 536.824572660431 123.109195013117 4.3605562736661 1.75449484548542e-05 -230.874068238801 340.489593210923 -0.67806497714537 0.498223575957633 GCN1 other 0.398036794479808 1 0.193573416302407 4.3605562736661 -0.67806497714537 0.0314484306175102 2313.401808252 928.244210977742 2.49223402730972 0.013203026231481 3137.6271896388 2567.2939682737 1.22215345356364 0.222554718525736 RPLP0 essential 1 1 1 2.49223402730972 1.22215345356364 0.00317470885602768 843.995899902594 266.890329326881 3.16233226595816 0.001715564585344 -632.539767624251 738.44606939275 -0.856582212082747 0.392318817535772 PXN other 1 1 1 3.16233226595816 -0.856582212082747 0.250420157079375 0.326855084563519 1.29843066077476 0.251730873613603 0.801411186835199 5.99096492226734 3.59256560642861 1.66760070060989 0.096376344144312 SIRT4 other 1 1 1 0.251730873613603 1.66760070060989 1.67251087107698e-10 198.400487237145 30.5745452499313 6.48907401942767 3.36230581568065e-10 -99.0485343367368 124.868792160518 -0.793220889086608 0.428248102726176 KIF16B other 2.07859651057447e-06 1 4.52162886092733e-06 6.48907401942767 -0.793220889086608 1.0778388630345e-15 147.342113403576 19.5016614755067 7.55536206946426 4.42306080823073e-13 -153.749785032537 73.0331405253503 -2.10520571793252 0.0360525475849797 TRMT6 other 1.49701039686862e-11 1 6.23297729095874e-09 7.55536206946426 -2.10520571793252 0.884411882517064 235.259456778516 695.552940215828 0.338233717631208 0.735408868074047 -652.515933267385 2604.82501398169 -0.250502789924441 0.80235930434176 CHGB other 1 1 1 0.338233717631208 -0.250502789924441 0.055346971018439 365.347006122474 165.369036032788 2.20928303681976 0.027865163261174 584.678250667272 457.55166538131 1.27784094104437 0.202234611122031 PEBP1 other 1 1 1 2.20928303681976 1.27784094104437 0.00355867367504056 5.38821712459682 10.0010684517202 0.538764148111599 0.590425371060001 91.0350833302755 26.8872377042142 3.38581018741121 0.000798400788776876 TBX5 other 1 1 1 0.538764148111599 3.38581018741121 3.49559591932174e-07 85.2713812604103 15.514380746414 5.49628004199394 7.93334222583887e-08 -6.57876592942634 43.5098042733703 -0.151201919643036 0.879911708419297 BRAP other 0.00374448234877745 1 0.000991429777963083 5.49628004199394 -0.151201919643036 0.690365682430955 52.6286631243363 126.395824491683 0.416379760454819 0.67741126970494 -231.429117959618 338.405083650798 -0.68388191886157 0.494544652363175 ERP29 other 1 1 1 0.416379760454819 -0.68388191886157 0.557316511059386 16.2410813630581 40.7362303092032 0.398688863446181 0.690389208831197 116.429700947367 110.614249926566 1.05257415771171 0.293332847905783 NOS1 other 1 1 1 0.398688863446181 1.05257415771171 0.610783080957881 -95.4945843518039 203.645636746766 -0.46892526585557 0.639451593286569 -681.539524140559 700.084468772384 -0.973510418443729 0.33105625450983 FUS other 1 1 1 -0.46892526585557 -0.973510418443729 0.00112171470481522 955.263272615827 288.330736883328 3.31308164693649 0.00102878384194587 -737.721672060103 932.682563161623 -0.790967582324432 0.429550576448512 FXYD5 other 1 1 1 3.31308164693649 -0.790967582324432 0.00177518673985532 37.3912980983455 12.6830784151684 2.94812480648446 0.003433003028057 -48.5799173300858 40.1391455370997 -1.21028777967345 0.227064501790327 ZNF302 other 1 1 1 2.94812480648446 -1.21028777967345 4.05020903649399e-07 265.220787972611 52.1991297007293 5.08094271864661 6.40649914098403e-07 -158.646121386219 176.410688835912 -0.899299937169811 0.369171248214309 GRAMD1A other 0.00430739731031136 1 0.00770438675643007 5.08094271864661 -0.899299937169811 0.113680853918736 55.0471802335777 46.0723772536135 1.19479791395527 0.233056343252593 -181.081559288746 135.560426102795 -1.33579957288886 0.182570004163788 CDIP1 other 1 1 1 1.19479791395527 -1.33579957288886 0.896355173667762 0.00502904913745062 1.22505640641652 0.00410515720836184 0.996727125600323 1.38976176500523 3.24802176177691 0.427879449996336 0.669026703558687 CMTM1 other 1 1 1 0.00410515720836184 0.427879449996336 2.11821583691926e-08 1675.77549541951 354.253191807769 4.73044572123109 3.39529773611492e-06 -3065.96402244695 1298.67136076771 -2.36084672001583 0.0188460029691942 GANAB other 0.000242196798793349 1 0.0392835948068497 4.73044572123109 -2.36084672001583 0.00283531259707249 33.795139031082 20.8748244249712 1.61894243242856 0.106450963246012 -115.058847618658 47.4823706772504 -2.42319088069005 0.0159427860599492 GMIP other 1 1 1 1.61894243242856 -2.42319088069005 0.0132167522688823 264.005212368682 89.4216896334037 2.95236215565829 0.00338674490575936 75.4146571385791 210.776334969458 0.35779470759612 0.720732832260472 BIRC5 other 1 1 1 2.95236215565829 0.35779470759612 0.0784852705786062 -34.6889303234759 15.5662043373074 -2.22847712722986 0.026545313702989 -62.2255124257706 86.0264839760964 -0.723329718358138 0.470007376367011 LAG3 other 1 1 1 -2.22847712722986 -0.723329718358138 4.90566606916189e-42 1545.8023112064 97.3503076477283 15.8787614395635 3.02227016954687e-42 -271.268891723377 538.005572807093 -0.504212048042563 0.614460441590253 MLF2 other 7.49978228653469e-38 1 4.62407335940672e-38 15.8787614395635 -0.504212048042563 5.51257283640049e-11 62.7965139395579 11.4881395628693 5.46620395721183 9.26719678936892e-08 -99.332303221289 34.5601281126319 -2.87418793407142 0.00432177098582669 OTUB2 other 6.95741817682106e-07 1 0.0011556194396343 5.46620395721183 -2.87418793407142 2.400538383896e-20 615.844259610063 67.0460159642326 9.18539678686652 5.28995705831293e-18 -348.510820269222 201.696618367571 -1.727896199202 0.0849715851378232 DDX24 essential 3.49206318705352e-16 1 7.7709469186617e-14 9.18539678686652 -1.727896199202 2.607252347556e-12 81.4580206586668 11.0893691461993 7.3455955505445 1.74584109636079e-12 -8.12910938066842 37.0892721231908 -0.219176837810887 0.826653350880675 ZBTB25 other 3.4011606873868e-08 1 2.44382836668584e-08 7.3455955505445 -0.219176837810887 3.58867665402758e-32 171.988527723343 13.0784812112674 13.1504969839442 7.1054039473657e-32 -81.618334345193 69.2290506260131 -1.1789607629622 0.239289649637137 NECAP1 other 5.43971607217501e-28 1 1.08137142674959e-27 13.1504969839442 -1.1789607629622 0.00596161878377172 6.21305873462904 2.68703994421752 2.31223162424491 0.0213992988730687 -4.56274870239318 4.97589082385564 -0.916971224633435 0.359848271650782 ANKRD24 other 1 1 1 2.31223162424491 -0.916971224633435 1.3651396804947e-11 140.903552574096 40.1641675405826 3.50819053903518 0.000515753290866019 -357.015410411249 81.354502391031 -4.38839154464066 1.55270844891527e-05 DHX32 other 1.74901695864981e-07 0.227456260681598 1 3.50819053903518 -4.38839154464066 1.53966520406152e-18 479.33498043246 61.5063588534487 7.79325893074849 9.58069575245133e-14 -572.769158139015 182.183635266451 -3.14391112737056 0.00182583593646662 RCOR1 essential 2.20587833785894e-14 1 1.36390784731897e-09 7.79325893074849 -3.14391112737056 1.76301309904595e-12 141.516421578584 18.7628138788106 7.54238796444083 4.87732997897614e-13 14.7643904618761 60.9567714340846 0.242210834244092 0.808772930814663 GPATCH2L other 2.30884195451058e-08 1 6.86923154238999e-09 7.54238796444083 0.242210834244092 6.57721866551896e-07 1133.18779404078 208.93880465611 5.42353918366613 1.15398329293241e-07 520.497595399896 612.853835845304 0.849301358588998 0.396348547290298 LTBP4 other 0.00689489832706353 1 0.00143313185149276 5.42353918366613 0.849301358588998 0.000682769228774483 266.828606900158 87.2333103275085 3.05879263206196 0.00241002109060892 -376.076163094616 255.870463773776 -1.46979122774842 0.142600779431653 BLVRB other 1 1 1 3.05879263206196 -1.46979122774842 1.073986668183e-05 461.334984351503 121.211934427443 3.80601948587544 0.000169206253359341 -465.876459575218 238.282431438161 -1.95514397248427 0.0514362896633196 SLC9A1 other 0.102189831477612 1 1 3.80601948587544 -1.95514397248427 2.49833355271693e-07 233.234406196242 42.103685103298 5.53952476188295 6.33743323555581e-08 -26.7683159327433 80.3525917086925 -0.333135688140443 0.739250019978333 SPTLC1 essential 0.00269670123680266 1 0.000795221122397544 5.53952476188295 -0.333135688140443 5.7785934317449e-07 443.579506432386 94.656023680211 4.68622586483232 4.13731219406902e-06 -413.277797626254 282.143754799649 -1.46477740724661 0.143972695238883 PAPOLA other 0.00608196958691151 1 0.0476204633537345 4.68622586483232 -1.46477740724661 8.09552712101901e-25 358.405596661065 36.5443862368781 9.80740500983943 5.63732255697714e-20 -360.446422811921 110.027277210892 -3.27597330361129 0.00117114671867275 CCNK essential 1.20574780940457e-20 1 8.37142399711106e-16 9.80740500983943 -3.27597330361129 2.57144533440226e-14 191.983132002253 46.5931098335088 4.12041893508003 4.82495212770498e-05 -259.400665242 66.0473357671727 -3.92749627564734 0.000105234882043593 PCBP4 other 3.49356563131891e-10 1 0.515642633887831 4.12041893508003 -3.92749627564734 0.866108399935608 -42.1668586128866 79.1412249648865 -0.532805230543187 0.59454407564712 16.0233877529548 270.85226632431 0.0591591422527324 0.952862864808016 RGS1 other 1 1 1 -0.532805230543187 0.0591591422527324 0.0285389515407111 72.7874510783577 38.0392673358157 1.91348194053741 0.0565897370394281 -173.991546743982 136.222560642186 -1.27725940493076 0.202448329502647 YPEL3 other 1 1 1 1.91348194053741 -1.27725940493076 5.70549667541325e-05 100.336801897731 31.7730597103087 3.15792066651917 0.0017404426410514 -96.596903155397 69.917811566077 -1.38157789827427 0.168065166524241 MRPS33 other 0.505621115375122 1 1 3.15792066651917 -1.38157789827427 0.0044092248928 141.975596262135 81.1903009082742 1.74867680836082 0.0813057610569527 -304.464473394377 178.662307365256 -1.70413378112223 0.0893268156471277 NDUFB2 other 1 1 1 1.74867680836082 -1.70413378112223 0.000173840768049353 140.97732599933 148.193448361385 0.951306063514647 0.342166987771716 -1085.24998668426 291.323584311692 -3.72523903016082 0.000230591347363004 NUDC essential 1 1 1 0.951306063514647 -3.72523903016082 1.67610292042277e-29 389.671523209999 53.9422724524707 7.22386183402533 3.76171720851775e-12 -492.269673368343 99.5881688258035 -4.94305377006586 1.24667104559195e-06 MAEA other 2.53024496867022e-25 0.0186576788683291 5.23743886941926e-08 7.22386183402533 -4.94305377006586 0.446199975557467 -249.427400075722 316.609010099141 -0.787808912947922 0.431393469988833 -817.724625452974 681.203506144153 -1.20041165096401 0.2308701664071 ICAM1 other 1 1 1 -0.787808912947922 -1.20041165096401 1.29102531099672e-08 313.481316895035 72.3096336093745 4.33526352226453 1.9526725799272e-05 -538.904925092609 165.462102327717 -3.25696892225656 0.0012468714746325 STRN4 other 0.000149023051648352 1 0.214754930340394 4.33526352226453 -3.25696892225656 0.775686257499981 -1773.83124345785 2754.25923881651 -0.644032057134918 0.520026291498444 -5746.64619563254 15726.2082511198 -0.365418421520861 0.715045906300709 LYZ other 1 1 1 -0.644032057134918 -0.365418421520861 2.12124619808437e-11 151.474729024913 34.3373710391689 4.41136652110392 1.4065449854477e-05 -288.994425341129 66.946441480199 -4.31680039971365 2.11530199696997e-05 MUL1 other 2.70671014875565e-07 0.308686020417828 0.156182755184112 4.41136652110392 -4.31680039971365 0.149823419831214 25.4984066355026 23.0808760205976 1.10474171832766 0.270104077665521 -85.5441074065673 67.9339484142788 -1.25922472347547 0.208869791403115 TFAP4 other 1 1 1 1.10474171832766 -1.25922472347547 5.7135176511779e-05 50.7278500351057 17.5624470346939 2.88842721830819 0.00413564843350366 -75.0186640319405 34.3936641672001 -2.18117684894658 0.0298979705127806 PDCD7 essential 0.506217663894362 1 1 2.88842721830819 -2.18117684894658 9.83587920950786e-08 283.312874922622 59.5839299949535 4.75485378266618 3.00747868271962e-06 -169.500281941434 116.687023964261 -1.45260609263073 0.147312984995112 SPG21 other 0.00108588106472967 1 0.0349017901129611 4.75485378266618 -1.45260609263073 0.220537458431967 62.3739815890687 35.813751978305 1.74162097360961 0.082535717473707 -39.5172427161883 222.686118043581 -0.177457144896901 0.85926159770641 FETUB other 1 1 1 1.74162097360961 -0.177457144896901 2.40224275028227e-23 549.265147740138 50.3882794797504 10.9006529576163 9.69747489219504e-24 430.735262759997 313.308986979021 1.37479383184383 0.170157240832102 DNAJB11 other 3.55748128889301e-19 1 1.45665770355662e-19 10.9006529576163 1.37479383184383 0.00699162566907655 770.96955771612 245.093108105398 3.14561908197181 0.00181553461744167 546.805920798908 1563.0153141323 0.349840411578095 0.726692253531397 P3H2 other 1 1 1 3.14561908197181 0.349840411578095 0.831109823334659 6.25360630139701 10.2802126994952 0.608314874818115 0.543412894198297 -1.82082419331031 67.5031100042148 -0.0269739304336737 0.97849744630948 CHRD other 1 1 1 0.608314874818115 -0.0269739304336737 7.68094937045981e-05 -7.98770286104467 12.3648322403081 -0.64600171727406 0.518742680211468 -127.551153964262 28.9320132282411 -4.40865116983137 1.42326314039138e-05 FLT3LG other 0.670086023078914 0.208764237432607 1 -0.64600171727406 -4.40865116983137 3.36450277290471e-08 194.283541671841 33.4496117311583 5.80824504730696 1.53500072151777e-08 19.6056487352436 90.2720094919512 0.217184139863328 0.82820455994251 RAB11FIP3 other 0.000380558908643252 1 0.000197262942722249 5.80824504730696 0.217184139863328 2.33063771698516e-06 146.388660765897 39.1365244143855 3.74046144762125 0.000217615435970934 -256.015444091261 108.771249083898 -2.35370510357742 0.0191917707003827 GNPTG other 0.0234368928820028 1 1 3.74046144762125 -2.35370510357742 0.0191088523614896 44.917725608443 20.6071331783864 2.17971734445597 0.0300186668096564 -65.0072860797528 50.0641507643237 -1.29847975222378 0.195072335488155 ZNF268 other 1 1 1 2.17971734445597 -1.29847975222378 3.4727093785188e-05 177.56474788778 50.3606232309265 3.52586478276023 0.000484345356731822 -255.702292398024 122.331388487947 -2.09024270515182 0.0373924258179334 GOLGA3 other 0.315044194819226 1 1 3.52586478276023 -2.09024270515182 5.64601002779801e-08 757.441320293398 128.826430660876 5.87954906774756 1.04002084861605e-08 541.518337408311 322.496706435307 1.67914377605261 0.0941062586040984 PABPC4 other 0.000630941620606428 1 0.000134339493015736 5.87954906774756 1.67914377605261 0.595987181933805 -20.5279692000195 30.1842732010455 -0.680088238775563 0.496940302005024 21.3865311340477 56.0440716781957 0.381602023080138 0.703009844713437 CD209 other 1 1 1 -0.680088238775563 0.381602023080138 4.2245489004461e-05 230.834765643856 75.8043317631818 3.0451395095072 0.0025188864473333 -254.797047544702 141.22444907078 -1.80419926734499 0.0721402606194536 CERS4 other 0.380082664573136 1 1 3.0451395095072 -1.80419926734499 7.52032629920644e-09 23.1906130253238 21.7970096632114 1.06393552985685 0.288160082863362 -201.195133819571 39.4710342498772 -5.09728558278649 5.90631358582107e-07 MCOLN1 other 8.78073298695344e-05 0.00887423616269615 1 1.06393552985685 -5.09728558278649 6.066916998524e-05 82.6658002466315 39.0002131579305 2.11962431876662 0.0348097407530554 -237.409392634972 75.2868454379271 -3.15339806381863 0.00176729235023247 USP48 other 0.536188197836645 1 1 2.11962431876662 -3.15339806381863 0.00111339058179022 193.146561730493 55.5672939046617 3.47590368647212 0.000579422881254568 20.8678790843444 151.572805645113 0.137675614009572 0.890583380189331 PDPR other 1 1 1 3.47590368647212 0.137675614009572 1.24511506590781e-06 488.867635536798 133.70327399373 3.65636248787537 0.00029896222127241 -770.811837239764 364.706987494074 -2.11350992350342 0.0353307970255207 AARS essential 0.0128084986829936 1 1 3.65636248787537 -2.11350992350342 1.28311010877035e-12 1109.31680370604 170.658789062365 6.50020318203859 3.07662124221607e-10 -404.21812740283 448.6027471183 -0.901060303351719 0.368233902333674 GLG1 other 1.68664823797863e-08 1 4.14020920565016e-06 6.50020318203859 -0.901060303351719 0.000243701031942827 92.4975603254268 33.8530200057401 2.7323281736679 0.00664148395347635 -246.127493630394 116.206272550096 -2.11802244602837 0.0349511279672945 TNRC6A other 1 1 1 2.7323281736679 -2.11802244602837 1.0310981564225e-10 172.880441630358 26.9321625793985 6.41910730787736 4.96062769016231e-10 -94.6383681594148 84.4642785695905 -1.12045434782755 0.263363022995595 PLEKHG2 other 1.28825403663427e-06 1 6.64972141866258e-06 6.41910730787736 -1.12045434782755 0.0879193266226955 7.57925999650592 4.21196799307168 1.79945811767163 0.0728911395983826 -10.3151989771879 13.209516199978 -0.780891504353893 0.435445409561515 DLL3 other 1 1 1 1.79945811767163 -0.780891504353893 0.00961302868311199 68.8871420902454 24.2317290411063 2.84284881088701 0.0047585606349776 -26.5478914906901 65.84184340169 -0.403206989949019 0.687065224285836 NAT14 other 1 1 1 2.84284881088701 -0.403206989949019 0.015057737613939 52.1140075215086 23.0706482791094 2.25888786873398 0.0245652224588249 -87.5222390303529 59.4730539209762 -1.47162846465975 0.142107040748188 PITPNM2 other 1 1 1 2.25888786873398 -1.47162846465975 3.92335522953062e-10 96.2522592790672 31.1316212605696 3.0917843460012 0.00216741979570173 -296.33446398846 66.3513132922701 -4.4661431595655 1.11131721714205e-05 EXOC1 essential 4.81944956395541e-06 0.163374744092053 1 3.0917843460012 -4.4661431595655 6.65601058964612e-07 123.041744527724 33.1660416235394 3.7098712570027 0.00024442880468301 -119.032605633053 48.250969220472 -2.46694745320369 0.0141503809187049 RBM27 other 0.00697283669371327 1 1 3.7098712570027 -2.46694745320369 0.00129966704680797 242.277281739352 74.6096780466047 3.24726346611514 0.00129037148095104 -186.172451418447 174.365222682122 -1.06771550286637 0.286463861352679 OSBPL8 other 1 1 1 3.24726346611514 -1.06771550286637 0.00115988147887031 -16.5917554545112 66.5566849664284 -0.249287587909166 0.80329876713832 -838.730770248079 230.572686580825 -3.63759811574242 0.000320809697165914 DTX2 other 1 1 1 -0.249287587909166 -3.63759811574242 0.114769464173094 -2.11760496183206 1.77808857418119 -1.19094458655257 0.234560746203781 -11.607689595088 6.18484174442004 -1.87679654140875 0.061458608973791 NLRC4 other 1 1 1 -1.19094458655257 -1.87679654140875 1.17227091030785e-19 250.229415379363 25.7471499631161 9.71872287759334 1.08439377409047e-19 19.3985172541322 95.0969932270332 0.203986651899923 0.838496072515634 PUS7 other 1.69791718648989e-15 1 1.60707157320208e-15 9.71872287759334 0.203986651899923 0.541846242727844 4.11616988600457 4.63389740177914 0.888273850090899 0.375071232396782 -9.28624954685961 20.3204687137617 -0.456989928611767 0.647993269527439 LAMB4 other 1 1 1 0.888273850090899 -0.456989928611767 0.000514219870600296 153.304030255081 49.2624082051246 3.11198814350966 0.00202858309430928 -365.654073854535 216.02446880081 -1.69265118847113 0.0915106333780873 NRCAM other 1 1 1 3.11198814350966 -1.69265118847113 0.000162911981394889 460.623583017767 152.697572869152 3.0165743591254 0.00276473791066048 -1511.99977940024 669.606161535565 -2.25804340858046 0.0246270325344609 LAMB1 other 1 1 1 3.0165743591254 -2.25804340858046 0.377643641154514 -2.80104878619157 3.06202539584926 -0.91476993952713 0.361009905194775 -16.5635137743059 13.4798156797943 -1.22876411427004 0.22007454052951 SLC26A4 other 1 1 1 -0.91476993952713 -1.22876411427004 4.627515442623e-18 413.456849388158 45.6757813181557 9.05199292614646 1.47714864138463e-17 -193.811071664534 201.076422825868 -0.96386771228954 0.335849271069672 DLD other 6.59976252426892e-14 1 2.16372732990021e-13 9.05199292614646 -0.96386771228954 1.35315909966851e-14 71.3628224868995 24.0584475540841 2.96622723999435 0.00324239497916438 -161.326902360796 36.5554502360536 -4.41321065173707 1.39529832419336e-05 WDR7 other 1.84760343468739e-10 0.204746076092134 1 2.96622723999435 -4.41321065173707 4.59426325037661e-27 244.278270413265 53.8634904955673 4.53513628927127 8.15766361011714e-06 -502.97045607159 81.8425271175325 -6.14558804311215 2.37457863399724e-09 TXNL1 other 6.89598913881529e-23 3.61957021180199e-05 0.0921489681398832 4.53513628927127 -6.14558804311215 3.20587736283112e-07 380.501837942212 130.952556716509 2.90564649887621 0.0039203487095363 -523.343455154211 194.885521231096 -2.68538910355289 0.00762224501530765 CMTM6 other 0.00343958582258151 1 1 2.90564649887621 -2.68538910355289 4.82551534772073e-07 5856.5247013215 1198.59623707553 4.88615308488781 1.64440809678928e-06 -8736.42029716528 4488.92941069916 -1.94621467567354 0.0525235860922457 ITGA6 other 0.00510732544402762 1 0.0193793494206616 4.88615308488781 -1.94621467567354 0.000235159862726457 20.2062358587096 5.19000368659587 3.89329894136605 0.000120896409113237 -17.9583795702489 19.4373713764039 -0.92390988588352 0.356244935135106 RAPGEF4 other 1 1 1 3.89329894136605 -0.92390988588352 1.45564633579375e-06 495.947659512221 96.9861208658613 5.11359414197163 5.51712959636305e-07 -268.618890775444 363.930081390341 -0.738105764022652 0.461003213643634 MAP3K20 other 0.0148912620151701 1 0.00665807199689093 5.11359414197163 -0.738105764022652 3.21052028638175e-06 231.433709345203 45.1286370353648 5.12831152343114 5.09085864712923e-07 -3.51842619673548 142.663770987521 -0.0246623664324927 0.980339741679825 FH ts 0.031941466329212 1 0.00615077541746154 5.12831152343114 -0.0246623664324927 0.378444788951818 -40.1216959475645 103.681444814481 -0.386970841497771 0.699039925273913 175.512185462833 193.695833745296 0.906122667014236 0.365565711239406 SEL1L3 other 1 1 1 -0.386970841497771 0.906122667014236 0.72707752721349 21.5222769843475 56.8742370949994 0.378418737264078 0.705370472823208 -151.009758381612 233.17202019065 -0.647632414292852 0.517687082495795 TF other 1 1 1 0.378418737264078 -0.647632414292852 3.06942100169066e-24 921.185278930756 81.6258064580747 11.2854661889791 4.33602127227256e-25 114.651834376743 334.77122786266 0.342478160709137 0.732215916401088 CDV3 other 4.56054572431198e-20 1 6.53395045518752e-21 11.2854661889791 0.342478160709137 7.17723020916871e-16 589.290155184132 67.1246498252781 8.77904252339524 1.02193571155242e-16 -63.1777502323173 125.149143130167 -0.504819678762056 0.614034042352429 ALKBH5 other 9.98783355907917e-12 1 1.49008446101459e-12 8.77904252339524 -0.504819678762056 0.000796786638602318 225.949713157889 64.0666517325519 3.52679135006341 0.000482110344690659 -163.237030762378 122.867156707564 -1.32856521739897 0.184938099070402 NLRP1 other 1 1 1 3.52679135006341 -1.32856521739897 7.43567223420454e-07 187.72707621109 40.7840307221649 4.60295544327025 6.01494880008078e-06 -208.276506434061 77.8484742508075 -2.67540897157533 0.0078477100886197 PITPNM3 other 0.00776655964862664 1 0.0685343266281204 4.60295544327025 -2.67540897157533 3.4475853834009e-34 422.49209495461 30.1672179835489 14.0050068649024 4.34627640007611e-35 -70.0632316799303 67.5769164232391 -1.03679237509328 0.300615446001304 SPAG7 other 5.23791647300099e-30 1 6.62894076539608e-31 14.0050068649024 -1.03679237509328 0.0163287211030614 34.3589301318527 20.2962473779232 1.69287107572535 0.0915011248677237 -72.5427431096655 54.8654880867508 -1.32219261396097 0.187094708616218 ORC6 essential 1 1 1 1.69287107572535 -1.32219261396097 0.0262606450499058 36.0445621070662 15.3722684316608 2.34477834337245 0.019659008162676 -80.5209529976119 72.8480536845249 -1.10532744424875 0.269861242752816 ZFHX4 other 1 1 1 2.34477834337245 -1.10532744424875 1.09352141076347e-14 39.8700930030925 10.2484064006004 3.89037001896769 0.000121777387933561 -117.244030634953 23.7258062012485 -4.94162472880617 1.25158473932333e-06 ZC3HC1 other 1.49659340277089e-10 0.0187299656239737 1 3.89037001896769 -4.94162472880617 0.0452213656715574 -26.5425790754259 27.3236437610481 -0.971414329199545 0.332075679324208 122.320534361658 60.4122587633762 2.0247634646598 0.0437217640113632 ESR1 other 1 1 1 -0.971414329199545 2.0247634646598 0.370292707543143 0.827250608272513 5.69966384727087 0.145140245186323 0.884691518007516 -16.8246695945359 12.6018905171226 -1.33509091922959 0.182795586178445 RGS17 other 1 1 1 0.145140245186323 -1.33509091922959 0.587011320008863 16.6181138407876 29.9314791040358 0.555205233360715 0.579143402843575 59.1101020308547 57.7057344158741 1.02433670811396 0.306452403884311 ANGPT2 other 1 1 1 0.555205233360715 1.02433670811396 0.00233263793406368 81.3639743854575 23.1807668948476 3.50997767910526 0.000512638053717324 4.96556496591605 55.8667703724514 0.0888822627979339 0.929231254363439 TMEM101 other 1 1 1 3.50997767910526 0.0888822627979339 0.407586482284174 35.1442540846371 26.3000084079913 1.33628299806773 0.182406208734686 20.0628376978642 107.222812077827 0.18711351912037 0.851690206372268 CD200 other 1 1 1 1.33628299806773 0.18711351912037 0.184295256914291 230.860471397703 128.134322257719 1.80170673501023 0.0725326712846318 416.9786410982 526.369011414355 0.792179311577968 0.428842988333999 CCDC80 other 1 1 1 1.80170673501023 0.792179311577968 2.46164025167487e-05 399.754857512846 160.909305228851 2.48434891285063 0.0134915764118805 -1421.30536345428 437.123577998564 -3.25149553808546 0.00127073186140367 PSME1 other 0.226618601569188 1 1 2.48434891285063 -3.25149553808546 7.42003128971896e-12 57.9369664024359 8.46129447782297 6.8472934672453 4.04564094610652e-11 -36.1807239569735 27.2687962404054 -1.32681778975497 0.185545459988811 PPP2R3C essential 9.57703438564026e-08 1 5.53443681427372e-07 6.8472934672453 -1.32681778975497 0.727343819667165 109.896548563229 1523.14774915477 0.0721509444006422 0.942526858026919 3294.9708281854 4176.60991634456 0.788910358923155 0.430748490354067 MYH7 other 1 1 1 0.0721509444006422 0.788910358923155 3.36369631167345e-10 2654.28136938782 407.425847157252 6.51475940446007 2.82440323812536e-10 -710.52139047649 1133.58968043293 -0.626788866148756 0.531244544631027 SLC7A8 other 4.14138289893235e-06 1 3.80362384078343e-06 6.51475940446007 -0.626788866148756 0.000149282427982285 37.1414888982061 15.100205769252 2.45966773339181 0.0144367266813853 -132.831792890399 45.0866798992086 -2.94614270084524 0.00345448428882948 OSGEP essential 1 1 1 2.45966773339181 -2.94614270084524 0.00448269280395534 51.3749003626799 16.2541664693791 3.16072192686498 0.00172429952721765 77.5369754095095 44.5704055273668 1.73965155784595 0.0828817135959189 SLC22A17 other 1 1 1 3.16072192686498 1.73965155784595 3.46886091319619e-20 218.516890627019 28.526850247369 7.66004268722842 2.24382450983554e-13 -359.400556985726 77.4955732449668 -4.63769144399572 5.1472261696655e-06 RNF31 other 5.03990802078274e-16 0.0763024807391213 3.17546044631925e-09 7.66004268722842 -4.63769144399572 1.85866767582823e-21 225.531315950711 23.9661668273288 9.4104041574782 1.12252088585351e-18 -146.189745552032 66.8328086508429 -2.18739491131932 0.029455619527697 SCFD1 essential 2.72331987862353e-17 1 1.65605506289968e-14 9.4104041574782 -2.18739491131932 2.0777524060665e-08 105.23275920757 18.0488279180185 5.83044836404661 1.37993651069299e-08 -13.9201994924658 50.3315307494823 -0.276570159603362 0.782293304841743 G2E3 other 0.000237653320205886 1 0.000177528832100653 5.83044836404661 -0.276570159603362 9.06531386012036e-11 689.608636977061 103.734991929277 6.64779187959271 1.32335429924412e-10 -228.969821769277 328.866450232337 -0.696239527040581 0.486795519261282 HECTD1 essential 1.13497729528707e-06 1 1.79407142348526e-06 6.64779187959271 -0.696239527040581 0.000175516850119507 529.935973878477 151.751222512159 3.49213643953356 0.000547209663598065 -664.221323111868 423.306728504889 -1.5691253608415 0.117616339224285 HNRNPC essential 1 1 1 3.49213643953356 -1.5691253608415 2.99496810727629e-18 883.661102273652 98.7664246682312 8.94697874547935 3.08705062673388e-17 -326.434307230841 273.983017049317 -1.19143993210383 0.234369391806314 SUPT16H essential 4.28040841891927e-14 1 4.51450283653563e-13 8.94697874547935 -1.19143993210383 1.22219356534174e-36 528.5715905978 40.3269618226445 13.1071513128716 1.11866033144157e-31 -377.975978903618 111.869015262175 -3.37873698108274 0.00081878418120133 TOX4 other 1.86176745808508e-32 1 1.70215356032149e-27 13.1071513128716 -3.37873698108274 1.0159417722747e-09 47.5044464606197 7.52521118343287 6.31270608925941 9.47825060680058e-10 -10.9844434874232 21.6328295249175 -0.507767302227888 0.611977619326748 GEMIN2 other 1.22695287837616e-05 1 1.26240819831977e-05 6.31270608925941 -0.507767302227888 0.0778992642611246 565.795309181086 619.120095822867 0.913870043951799 0.361473182221823 -3019.17652752518 1685.69450182993 -1.79105794332701 0.0742289787808098 TGM1 other 1 1 1 0.913870043951799 -1.79105794332701 3.47211779073378e-17 281.320539786582 39.0429089231922 7.20541956389609 4.17898706948655e-12 -411.16990322203 106.30315079629 -3.86789949443699 0.000133005084426964 TINF2 other 4.90332474407424e-13 1 5.81464260848359e-08 7.20541956389609 -3.86789949443699 0.283206049548342 48.3338612534792 79.5415997971929 0.607655131110211 0.543847204485626 -133.100945486554 119.207997914457 -1.11654375390204 0.265027124279167 SEMA6A other 1 1 1 0.607655131110211 -1.11654375390204 0.000111308033016698 160.256775907006 53.020063912069 3.02256851619008 0.00271143056785024 -214.070219976277 113.863224362447 -1.88006462292736 0.0610190287802936 TRPM7 essential 0.954021150986115 1 1 3.02256851619008 -1.88006462292736 5.47449139263827e-08 175.365679418068 33.3057229669102 5.26533171468148 2.58178192387422e-07 -23.8869159068674 66.5050531823187 -0.359174450118597 0.719702958888376 TYRO3 other 0.00061232186226659 1 0.00316268285674592 5.26533171468148 -0.359174450118597 0.0165526783699058 -59.8499199614232 37.8997112930812 -1.57916559043417 0.115286028451329 -217.652919061097 76.7353527403353 -2.83640996344426 0.00485312802086265 WDR76 other 1 1 1 -1.57916559043417 -2.83640996344426 0.0986737584921515 123.620644153826 78.9306262026267 1.56619363232307 0.118291612935947 -118.472578885188 159.497949480569 -0.742784338425747 0.458157178797164 CAPN3 other 1 1 1 1.56619363232307 -0.742784338425747 0.00176850613899775 123.282379958653 43.8229903398762 2.8131895838809 0.00520948886912632 -85.7504367292811 88.6666563181677 -0.967110301549862 0.334221523396987 SNAP23 essential 1 1 1 2.8131895838809 -0.967110301549862 0.12439506448028 58.338716926857 33.9907938182742 1.71630934066308 0.087098015521446 111.389716237678 63.2107791670207 1.76219495639113 0.0790155476157259 TBX15 other 1 1 1 1.71630934066308 1.76219495639113 0.0078156199223343 -45.4432603328066 193.914305509153 -0.234347126755234 0.814870201826245 -1053.09644697135 360.73871016775 -2.91927763028714 0.00376539051423896 PHGDH other 1 1 1 -0.234347126755234 -2.91927763028714 0.895590173222414 -24.2518077466553 61.0568242573009 -0.397200608476708 0.691484328102915 -92.5504973268502 278.272725381747 -0.332589179194207 0.739662181725573 COL9A3 other 1 1 1 -0.397200608476708 -0.332589179194207 2.23345593502394e-08 2241.38363884988 513.744461798253 4.36283756909884 1.73573329356907e-05 -3591.08695576379 1122.87688580448 -3.19811281286726 0.00152211037920756 EZR other 0.000255060667779734 1 0.191572883611218 4.36283756909884 -3.19811281286726 0.789948578034163 -707.1617205679 1056.77389723226 -0.669170313933747 0.503869328604907 -848.641351633897 3019.29641911545 -0.281072552618904 0.778836402507126 MYL6 other 1 1 1 -0.669170313933747 -0.281072552618904 0.00265243764536332 217.514318992568 63.4007052382763 3.43078705788986 0.000681294156428271 12.8318465554931 151.334720728141 0.0847911602423636 0.932480777095167 AGO1 other 1 1 1 3.43078705788986 0.0847911602423636 0.0978162808632079 11.4216613669312 22.190580954382 0.514707631603298 0.607116016226056 -104.293508335848 52.9421805809281 -1.96995112765375 0.0497141791921775 CLSPN other 1 1 1 0.514707631603298 -1.96995112765375 6.69893827630546e-06 124.441663390557 39.1459098187294 3.17891866523989 0.00162416262506642 -333.218056465586 96.7354963936655 -3.44463065666768 0.000648790324737459 RFFL other 0.0649395076505051 1 1 3.17891866523989 -3.44463065666768 0.0020371692055885 167.177673666209 54.5937915421503 3.06221035293246 0.00238525821614602 -175.55948657906 134.506986024344 -1.30520719977538 0.192768874454032 UNC13D other 1 1 1 3.06221035293246 -1.30520719977538 0.000271531441790641 178.105480801638 52.2895002079821 3.40614234393562 0.000743184518653432 -206.023550583734 126.110254722049 -1.63367801482772 0.103312991755802 MFSD11 other 1 1 1 3.40614234393562 -1.63367801482772 3.12247957587172e-07 179.780733938422 98.022792762394 1.83407071837065 0.0675719541137098 -540.517428632376 180.209481932128 -2.99938395492392 0.00291751673361261 DPYSL2 other 0.00335073283286794 1 1 1.83407071837065 -2.99938395492392 0.0302423691040502 103.190617194576 43.5580998242165 2.36903394801457 0.0184279717277171 -184.53836049478 142.225708582637 -1.29750354091263 0.195392563628378 TGFB2 other 1 1 1 2.36903394801457 -1.29750354091263 4.37931001926419e-06 87.8846030192492 17.4143541178964 5.0466760021224 7.55488159423828e-07 -35.2435401053963 56.861269520986 -0.619816272170794 0.535819841509152 GPATCH2 other 0.043114307139656 1 0.00905277979850106 5.0466760021224 -0.619816272170794 1.70446054730188e-05 189.656215223466 69.024652597079 2.74765910566121 0.00634251099344616 -539.067560837046 173.100345005653 -3.11419114051703 0.00201123946681077 NUP50 other 0.159384105778199 1 1 2.74765910566121 -3.11419114051703 0.00146728121293808 111.582180837322 30.8695122778475 3.61464022602637 0.000350029201738522 35.8856601188905 117.039408291278 0.306611769854314 0.759341466010492 CDC45 essential 1 1 1 3.61464022602637 0.306611769854314 0.242329329272542 -94.5740861407259 70.1489207144806 -1.34819018136659 0.178578306934349 -290.171815654455 213.056842546965 -1.36194553615658 0.174200747113527 ADA2 other 1 1 1 -1.34819018136659 -1.36194553615658 0.527053261184121 8.71239988706361 7.86490505645202 1.10775652401758 0.268804150883557 0.406215034167554 18.7158894151925 0.0217042869380182 0.982697456326361 VNN3 other 1 1 1 1.10775652401758 0.0217042869380182 7.71208459786682e-07 75.0228639134882 35.160308279181 2.13373737561654 0.0336316154050308 -360.436616082952 82.769329717032 -4.35471227464565 1.80088175139929e-05 ECHDC1 other 0.0080491026947936 0.263414973777175 1 2.13373737561654 -4.35471227464565 1.58694893212126e-21 182.443580952763 54.6786342857448 3.33665211898548 0.000947770858975378 -525.436037422784 78.3238493395999 -6.70850630878184 8.92895997398447e-11 LRRFIP2 other 2.3269432191694e-17 1.36577371762066e-06 1 3.33665211898548 -6.70850630878184 2.79276475598232e-16 159.358167336375 31.250253158301 5.09942004402753 5.84506188876072e-07 -161.255516151635 44.5669493134898 -3.61827584422129 0.000344544705351318 SEC22C other 3.90735717009487e-12 1 0.00704271506976779 5.09942004402753 -3.61827584422129 0.000234240011660411 30.753388441317 10.111353305724 3.04147105846926 0.00254889812351955 -11.0160126341883 14.4839044223067 -0.760569271447451 0.447474416954211 XYLB other 1 1 1 3.04147105846926 -0.760569271447451 0.0274491668173829 -33.5918163756957 317.749497557068 -0.105717921299506 0.915872606428101 -1202.14513840652 469.538800564736 -2.56026794156445 0.0109193956642087 GABRP other 1 1 1 -0.105717921299506 -2.56026794156445 0.00100544465054914 50.544774141679 14.1518869220935 3.5715925671205 0.00040950890315691 -36.6378941726468 41.2826121520478 -0.88748972661192 0.375483926674466 KRT31 other 1 1 1 3.5715925671205 -0.88748972661192 0.000101532494116806 136.101819497117 37.9417943536276 3.58712132137485 0.000387300372442196 -239.356891071311 109.722078823285 -2.18148337725912 0.0298843380802945 CDC6 essential 0.874175941808116 1 1 3.58712132137485 -2.18148337725912 7.31964812907127e-11 158.065230777057 34.4581099207277 4.58717065853851 6.45752820002397e-06 -181.466578102595 51.1896189076851 -3.54498787009628 0.000451197567520319 CDC23 essential 9.19786983899095e-07 1 0.0734543832752726 4.58717065853851 -3.54498787009628 0.0155643232849053 71.5776046951515 27.8481543258996 2.57028181679466 0.0106165003344444 -58.5553266787048 75.5659043031015 -0.774890834943683 0.438979965158655 AAAS other 1 1 1 2.57028181679466 -0.774890834943683 0.000104905700228935 708.580021438221 221.802242877595 3.19464768365423 0.00153947280682399 2036.23532001465 715.174158184849 2.84718805442122 0.00469577854512493 FMO2 other 0.901454682067242 1 1 3.19464768365423 2.84718805442122 0.00350169131489729 119.117696011142 36.1129217005408 3.29847850580748 0.0010815774847337 -103.695710350686 116.441691669604 -0.890537649048552 0.373846305850419 SUCO other 1 1 1 3.29847850580748 -0.890537649048552 0.00953003658615465 121.34345464965 42.0787513664718 2.8837227985414 0.00419631598316072 -94.8525465510816 153.178131544694 -0.619230340483724 0.53620522606621 MSH2 ts 1 1 1 2.8837227985414 -0.619230340483724 3.66243688788143e-05 74.9026363970545 45.8919076307189 1.63215347245484 0.103636967015019 -254.645224954404 77.0128992251573 -3.306526926222 0.00105268179094129 MAP3K1 other 0.331450538353269 1 1 1.63215347245484 -3.306526926222 2.25801816731121e-05 79.3208593308917 40.6753908537221 1.95009458215528 0.0520516680788387 -315.933154788619 88.493535269403 -3.57012694573469 0.000412447813781055 DHPS essential 0.208776359749595 1 1 1.95009458215528 -3.57012694573469 5.79025093974987e-24 560.403117062316 53.5404548116811 10.4669099101499 3.43425769102824e-22 -364.353256608861 176.704973018248 -2.06192983924247 0.0400369696727669 HOOK2 other 8.58983726911893e-20 1 5.14005348616197e-18 10.4669099101499 -2.06192983924247 3.99861282131929e-37 1242.16419548008 132.230359789008 9.39394097892592 1.1467067388083e-18 -732.618059001153 250.021498683285 -2.93022025249595 0.00363155601659589 ARCN1 essential 6.09468566225486e-33 1 1.69162178109001e-14 9.39394097892592 -2.93022025249595 0.000377501441527384 124.630431503145 31.4101412157145 3.96784053427918 8.96235450587958e-05 -16.7897077048418 62.9409039670182 -0.266753520312321 0.789831297060512 EPB41L4B other 1 1 0.933877339512652 3.96784053427918 -0.266753520312321 0.0331441763732519 50.4748842444364 20.2722766354569 2.48984784255332 0.0132870342272567 43.1363194163949 40.580425215664 1.06298342580561 0.288590976644748 TMEM38B other 1 1 1 2.48984784255332 1.06298342580561 7.0358436140292e-11 218.96290881176 34.5842946371646 6.3312816152237 8.27574191913728e-10 -169.3120122826 69.1889955969011 -2.44709452452557 0.0149421103332713 PSMD5 other 8.84827692900312e-07 1 1.1040667294321e-05 6.3312816152237 -2.44709452452557 7.99309312322909e-06 758.750924228548 156.735447606188 4.84096568974605 2.0142025090228e-06 -105.886321121717 313.391940642304 -0.337871870299856 0.735681287151014 PTGS1 other 0.0769734867766962 1 0.0236024250007292 4.84096568974605 -0.337871870299856 1.68226022859019e-14 641.129427237577 91.7659097380144 6.98657517882141 1.64012030986454e-11 -673.534223446236 179.329169971843 -3.75585424028889 0.0002051968092794 NUP188 other 2.29258423952271e-10 1 2.25942973886939e-07 6.98657517882141 -3.75585424028889 0.0512817336230278 138.295853004256 62.335648752951 2.21856763779505 0.0272175817828864 -93.208624026403 121.816480460306 -0.765156107566043 0.444742527256485 CRAT other 1 1 1 2.21856763779505 -0.765156107566043 0.0161772041119032 -23.4100918539275 13.0866294178961 -1.78885571726468 0.0745838178732244 -63.2973611585843 25.6234328061583 -2.47029200331704 0.014021267169504 SH2D3C other 1 1 1 -1.78885571726468 -2.47029200331704 1.76070083264309e-08 176.990330380281 47.9631591816582 3.69013078788113 0.000263353503397982 -403.531296992571 91.226442772058 -4.42340274081332 1.33340487384203e-05 NANS other 0.00020216366960408 0.195703833333795 1 3.69013078788113 -4.42340274081332 3.69489308282411e-13 687.996522059243 101.781011947114 6.75957635808074 6.56489995286435e-11 -630.96422386633 193.588575483707 -3.25930506120922 0.0012369789822302 TBC1D2 other 4.91014341776496e-09 1 8.94861512574939e-07 6.75957635808074 -3.25930506120922 0.288678714208882 34.6792516791639 21.9984658895507 1.57643955052505 0.115912588533385 1.95095040816078 44.2568297292652 0.0440824708885712 0.964866159955236 WHRN other 1 1 1 1.57643955052505 0.0440824708885712 1.29351379569432e-05 57.5079370334489 25.3209488023288 2.27116043250954 0.0238012168581091 -126.81770786141 46.3104915822837 -2.73842283958663 0.00651915459741405 CWF19L1 other 0.122322798158682 1 1 2.27116043250954 -2.73842283958663 0.00666632105294052 21.7550236954278 7.6112633154991 2.85826712250609 0.00453888445196115 0.463543459267693 13.9404792873192 0.033251615652078 0.973494668133742 SEMA4G other 1 1 1 2.85826712250609 0.033251615652078 0.00065216233856311 119.654729478694 44.1466841186236 2.71038996172799 0.00708398590769229 -106.782615074792 85.6110969483175 -1.24729876010415 0.213202898793214 BTAF1 other 1 1 1 2.71038996172799 -1.24729876010415 6.69856626641333e-05 35.6393965557573 15.3871603735902 2.31617762410062 0.0211801002483307 -74.9702360952208 30.6256619210324 -2.44795479975355 0.0149037584617549 IKZF5 other 0.588402060841747 1 1 2.31617762410062 -2.44795479975355 0.00996981607051903 -75.7642870477595 36.5762804119604 -2.07140491582038 0.0391220526535474 -197.727570341341 66.9887680454995 -2.95165258461003 0.00339432672219967 BLNK other 1 1 1 -2.07140491582038 -2.95165258461003 0.353592915707587 -9.99043591895996 15.1415862073264 -0.659801145148583 0.509856037595626 -40.0519005227651 27.7315296924464 -1.44427303386999 0.149640564564363 TLL2 other 1 1 1 -0.659801145148583 -1.44427303386999 0.069657697645578 32.6281354946247 58.6124580343163 0.556675774892799 0.578139283080185 254.018639679236 112.60870825415 2.25576372926625 0.0247625354690506 CYP26A1 other 1 1 1 0.556675774892799 2.25576372926625 0.0609474716899132 28.744541892144 16.4192853470242 1.75065730844087 0.0809632240452602 -22.2622847471357 31.4541077538484 -0.70777034660638 0.47960305104488 TDRD1 other 1 1 1 1.75065730844087 -0.70777034660638 0.161964653144958 1.54957037781023 61.3905268539068 0.0252411969276269 0.979878359184435 -189.459466080364 112.457693721919 -1.68471769080426 0.0930210842168756 SORBS1 other 1 1 1 0.0252411969276269 -1.68471769080426 0.131660967089036 -49.5007970067537 39.9977366852713 -1.23758995155798 0.216775447704476 -145.606786067548 73.2551007094325 -1.98766754338513 0.0477004693467149 CRTAC1 other 1 1 1 -1.23758995155798 -1.98766754338513 0.424022032552691 -54.9237110925865 42.3179927545779 -1.29788081894893 0.195265951266817 -66.5097348008534 84.6519659480609 -0.78568446764321 0.432635542134294 BAMBI other 1 1 1 -1.29788081894893 -0.78568446764321 0.41736532344532 32.1489364736306 24.5213779091635 1.31105750226282 0.190778358114169 32.825331005153 63.9937529022266 0.512945866064543 0.608343101483951 IL11 other 1 1 1 1.31105750226282 0.512945866064543 0.00089521167358908 -58.9039171119046 24.193135175043 -2.43473682454634 0.0154522761243056 -182.085451289468 48.9123244341959 -3.7226906182804 0.000233071092797102 MYO3A other 1 1 1 -2.43473682454634 -3.7226906182804 1.90934502998886e-17 436.777621826297 85.5784616368933 5.1038265174657 5.72978305997669e-07 -759.097362985152 171.189240056525 -4.43425861774084 1.27288909351308e-05 WAC essential 2.70706938351821e-13 0.186898305600526 0.0069072534788019 5.1038265174657 -4.43425861774084 0.266654700907039 13.5541280339875 18.9540286118768 0.715105390602521 0.475098209129718 -35.481269506682 38.1428068738356 -0.930221774817015 0.353001703016173 CREM other 1 1 1 0.715105390602521 -0.930221774817015 1.52153268746257e-05 153.663570565213 47.6056055626529 3.22784614855868 0.00137651117325077 -333.91943421204 134.259404093705 -2.48712137869304 0.0133873082483649 NUBP2 essential 0.142917565333359 1 1 3.22784614855868 -2.48712137869304 0.790807505453901 -1.63610077066201 7.64251270328303 -0.214078907576978 0.830621868159221 -14.3080272613638 20.876968262769 -0.685349859293513 0.493619338330801 TPSD1 other 1 1 1 -0.214078907576978 -0.685349859293513 0.00585929870696435 147.304793055788 58.1186557967072 2.53455264985901 0.011738414179184 -98.1256650143534 130.165204023438 -0.753854808975559 0.451494224029347 HIVEP1 other 1 1 1 2.53455264985901 -0.753854808975559 0.0653466797203141 26.4730981222586 23.4251379180825 1.13011493101278 0.259279473009061 -103.353328145547 64.4679706181741 -1.60317328364003 0.109889148294925 TREM2 other 1 1 1 1.13011493101278 -1.60317328364003 0.588562654500264 203.467342729461 279.931860850779 0.726845962124768 0.467858415917752 593.489177602977 642.631009791095 0.92353025073581 0.356435582237103 CRISP3 other 1 1 1 0.726845962124768 0.92353025073581 0.0756816353238949 489.500857604493 228.816226449243 2.13927510824097 0.0331697721956835 9.984047064207 529.466180785843 0.0188568173502385 0.984967079996257 FKBP5 other 1 1 1 2.13927510824097 0.0188568173502385 1.24499066852943e-09 411.941775412324 68.9770436346661 5.9721576006382 6.22510354733977e-09 -85.4317408143833 160.120551187957 -0.53354638227606 0.594025804716632 SRPK1 other 1.49884426584258e-05 1 8.10072724615324e-05 5.9721576006382 -0.53354638227606 1.39397403116619e-06 183.570315324809 38.9887564577514 4.70828854271685 3.72659106909698e-06 -55.0870717260876 90.5069403555978 -0.608650248363859 0.54318809324245 BRPF3 other 0.0142840518973599 1 0.0430085875284482 4.70828854271685 -0.608650248363859 4.60758121019806e-06 118.389965548365 27.9306009318166 4.23871888175181 2.94934132136964e-05 -106.63696458361 77.6635976416763 -1.37306238471736 0.170700354958956 MRPS18A essential 0.0452925232962469 1 0.320268974087529 4.23871888175181 -1.37306238471736 6.33232204971403e-06 229.623273254801 49.2457616306085 4.66280276010756 4.59797340857157e-06 -47.4502019286739 132.422470125211 -0.358324398297417 0.72033831134647 TMEM14A other 0.0615058440688724 1 0.0527617448633588 4.66280276010756 -0.358324398297417 0.00867580669091617 35.9291761253391 14.7016820204429 2.44388200447942 0.0150732788723964 -43.8088495978087 39.4118580128628 -1.11156519399595 0.267164824127607 EFHC1 other 1 1 1 2.44388200447942 -1.11156519399595 1.58684623435207e-19 7700.37369725958 837.801862382787 9.19116326067717 5.20496103829003e-18 -2275.75913185143 2329.58492022363 -0.976894687158677 0.329363853257824 HSP90AB1 other 2.29457965487309e-15 1 7.6471287574557e-14 9.19116326067717 -0.976894687158677 4.3537078513065e-16 259.356282488115 32.8292787169309 7.90015171287811 4.55247871466627e-14 -142.954731605167 91.2664461043115 -1.56634489132818 0.118259310660686 CDC5L essential 6.07734078963874e-12 1 6.50503683538663e-10 7.90015171287811 -1.56634489132818 1.39548734188953e-05 1124.65872045623 272.8327389524 4.12215456537437 4.79056595228781e-05 -479.297778052886 631.675722240866 -0.758771884334228 0.448549287017914 ITPR3 other 0.131552591719926 1 0.51215940595909 4.12215456537437 -0.758771884334228 3.07223938156444e-06 42.9048430847815 9.15832236776098 4.68479284326294 4.14968747641115e-06 -3.49242479279648 20.7613996901497 -0.168217212948965 0.866518667493579 ZNF184 other 0.0306302266341975 1 0.0477504537910631 4.68479284326294 -0.168217212948965 4.43952060050349e-08 20707.570367866 4143.09482413898 4.99809230703994 9.58010635057109e-07 -7983.41087618311 9268.34037364224 -0.861363583375372 0.389686845085169 DSP other 0.000498780139466567 1 0.0114319409081365 4.99809230703994 -0.861363583375372 0.0243280206893933 35.8597626021406 19.8635924996769 1.805300959669 0.0719703205968183 -51.5714556740828 41.8376344297259 -1.23265706527234 0.218611405741093 SIRT1 other 1 1 1 1.805300959669 -1.23265706527234 0.0029509794826514 162.717644361445 92.6365065453844 1.7565174943393 0.0799565659986331 -395.32632354456 193.878049326727 -2.03904632276524 0.0422667890663998 HNRNPH3 other 1 1 1 1.7565174943393 -2.03904632276524 2.6204615396913e-21 82.7910189777489 9.01347352190115 9.18525125486655 6.39851936910616e-18 -52.9136133874857 19.9812949472549 -2.64815736553426 0.00851279571025904 IFT74 other 3.83583160180012e-17 1 9.39302643384785e-14 9.18525125486655 -2.64815736553426 1.28459247262617e-25 137.191269534531 15.7759968438707 8.69620290193154 1.95065588521707e-16 -335.769574861367 53.0858964848176 -6.32502410423447 8.70325886504215e-10 JAK2 og 1.91943807259803e-21 1.32872653092598e-05 2.84015496887605e-12 8.69620290193154 -6.32502410423447 0.00972154816755101 -38.1683659707611 12.7645272773348 -2.99019032522531 0.00300497418362808 -46.1339618061174 29.775970024342 -1.549368896073 0.122284558224802 IL12RB1 other 1 1 1 -2.99019032522531 -1.549368896073 4.00704414182721e-07 367.960107308708 66.9938479970691 5.49244622170092 8.1094420418522e-08 -36.2822994399682 137.315406222712 -0.264225992101149 0.791776405166863 ABL1 og 0.00426389567131833 1 0.00101295040544776 5.49244622170092 -0.264225992101149 0.00120693064343152 145.713230440074 130.159074691073 1.11950112418914 0.263768622841675 -847.691788631557 283.270860208363 -2.99251320099791 0.00298282801646543 ACOT7 other 1 1 1 1.11950112418914 -2.99251320099791 0.000111650015994073 171.040534626781 85.6319824395757 1.99739080836382 0.0466291164040276 -553.464850776053 181.967126672977 -3.04156503922114 0.00254812518173598 SH3GLB1 other 0.956728987053211 1 1 1.99739080836382 -3.04156503922114 0.00724776153500446 -24.5673311493693 23.0166972295847 -1.06736995774492 0.286611907053128 -153.501649589926 48.5287861773451 -3.1631050698232 0.00171115654492261 CDC7 essential 1 1 1 -1.06736995774492 -3.1631050698232 0.075727233159646 -2.92188255651274 4.02667841037587 -0.725630968935511 0.46859703000106 15.5390811889815 8.52901114533442 1.82190888535557 0.0694051081042127 SYDE2 other 1 1 1 -0.725630968935511 1.82190888535557 0.192012873707206 57.2170955989411 51.2681887875765 1.11603504925858 0.265244474652603 -118.044346010401 99.0406574591857 -1.19187764942945 0.23419238660449 PCSK5 other 1 1 1 1.11603504925858 -1.19187764942945 0.0411635089515096 1557.53198750365 1251.80052313226 1.24423337322657 0.214324264219945 -3226.8779804612 2292.74675454273 -1.4074288728433 0.160270845230147 SCD essential 1 1 1 1.24423337322657 -1.4074288728433 5.21618783000424e-06 110.074761455303 31.7773445920898 3.46393831417567 0.000605306557446824 -169.287497310009 71.1673887795066 -2.37872289841211 0.0179628075370605 TMED1 other 0.0510143169774414 1 1 3.46393831417567 -2.37872289841211 0.0016800457007732 958.477701063631 473.250584257353 2.02530695776682 0.0436656312022319 -1669.97119875636 906.597002073562 -1.8420215320995 0.0663971461785766 ABLIM1 other 1 1 1 2.02530695776682 -1.8420215320995 6.21897580814998e-05 232.11090196587 65.5827463248582 3.53920680320598 0.000462201956191235 -461.482748670605 220.805475502568 -2.08999685184545 0.0374248691577006 ERMP1 other 0.548389286762665 1 1 3.53920680320598 -2.08999685184545 8.94781363786775e-11 338.182624540172 87.5400596314953 3.86317562455144 0.000135645060116527 -585.845656816954 175.176250484973 -3.3443212489995 0.000923456973836895 RAB18 other 1.12100711063995e-06 1 1 3.86317562455144 -3.3443212489995 0.849217709967474 -37.4400835283167 112.501772865381 -0.332795498015104 0.739511444400528 -126.235027171863 221.874347511708 -0.568948274496677 0.569799259833586 NRP1 other 1 1 1 -0.332795498015104 -0.568948274496677 0.0787671335384049 10.3612098273394 14.7346348444352 0.703187417722302 0.482451839271189 -45.2076021452168 29.6006356121148 -1.52725106101149 0.127689479507922 PRTFDC1 other 1 1 1 0.703187417722302 -1.52725106101149 0.000395105733291827 146.700459636823 66.9023569132546 2.19275473100349 0.0290468851610451 -332.626190190563 139.20983772548 -2.38938709810507 0.0174570236458894 PALMD other 1 1 1 2.19275473100349 -2.38938709810507 0.000521460200229531 131.670871332336 60.946521627154 2.16043291424972 0.0314834597694236 -275.876032100645 126.812470828532 -2.17546452882909 0.0303292168442909 TSPAN15 other 1 1 1 2.16043291424972 -2.17546452882909 0.000353724376535459 186.764184261908 51.8300686648022 3.60339449808098 0.000364069158585994 -28.1922643692899 107.839388053341 -0.261428267335355 0.793930440438686 H2AFY2 other 1 1 1 3.60339449808098 -0.261428267335355 3.56445753661615e-06 47.6296780798548 41.9545426613499 1.13526867553565 0.257112361856249 -370.44619497213 88.899323332849 -4.1670305361621 3.97534866969055e-05 WASHC2A other 0.0353237741878661 0.575431719937707 1 1.13526867553565 -4.1670305361621 0.00060004404523018 36.6476132303832 16.0818394218959 2.27881974623415 0.0233383036955755 -87.2995369331082 37.5143049294841 -2.32709994486652 0.0205855506187988 MAST3 other 1 1 1 2.27881974623415 -2.32709994486652 0.000257592452544176 21.922390374019 15.0903097984914 1.45274621043304 0.147308943010747 -123.384370087097 38.3169739331259 -3.22009692890775 0.00141787396868815 MZF1 other 1 1 1 1.45274621043304 -3.22009692890775 5.61492280697237e-06 40.7497544859683 10.5674872216707 3.85614419314396 0.000139342900928377 -47.7760716331663 24.7958150334929 -1.92677964279992 0.0548951469121928 OCEL1 other 0.0548072615188573 1 1 3.85614419314396 -1.92677964279992 9.46737779403855e-07 330.216775546802 81.4227129222978 4.05558552024581 6.29167329240097e-05 -418.787230067995 191.052280149084 -2.19200330789668 0.0291016243129556 MYO9B other 0.009822404461315 1 0.665533200870175 4.05558552024581 -2.19200330789668 0.0518730919103268 86.2789844633859 94.358279912889 0.914376401763981 0.361207553132317 -541.086813160921 278.352425355723 -1.94389113897403 0.0527848606358935 KCNK6 other 1 1 1 0.914376401763981 -1.94389113897403 0.000290119365836946 7.71941338917424 2.00583097258716 3.84848648498911 0.000143487404712091 -1.84523280533289 5.91710570167993 -0.311847193266973 0.755359740334361 CATSPERG other 1 1 1 3.84848648498911 -0.311847193266973 2.10273681068363e-15 587.143729490052 88.0431688667274 6.66881641185386 1.13268633197117e-10 -931.631795847724 259.723148966703 -3.58701871417384 0.00038675333094009 PSMD8 other 2.90976719862401e-11 1 1.53762169565086e-06 6.66881641185386 -3.58701871417384 6.72664495161526e-13 222.361496586498 33.0738146969833 6.72318868034234 8.47250139130208e-11 -221.566262103431 113.756480916085 -1.94772429947858 0.0523446285884827 FBXL19 other 8.89329729053053e-09 1 1.15259908927273e-06 6.72318868034234 -1.94772429947858 2.85950405177597e-05 11.8751037158298 2.58340563601074 4.59668568896026 6.25015799422722e-06 5.52952257080706 8.88112405059365 0.622615171154765 0.533993683785001 STX1B other 0.261959166183197 1 0.0711767992382595 4.59668568896026 0.622615171154765 0.0482827304269075 13.3963817991167 33.4206207029795 0.400841801179426 0.688810960075781 -255.941546561955 114.949310686831 -2.22656008141924 0.0266903676655722 HSD3B7 other 1 1 1 0.400841801179426 -2.22656008141924 7.19566669052828e-05 113.168149848289 34.3629094474325 3.29332270369628 0.00110387327513114 -226.002944982374 118.190287047069 -1.9121955841631 0.0567667203151449 SETD1A essential 0.630412358757182 1 1 3.29332270369628 -1.9121955841631 0.0776059650625371 190.945728174734 96.1695114003665 1.98551209623809 0.0479598688381045 -163.024205899981 330.93607293464 -0.492615399869623 0.622629739420622 BCL7C other 1 1 1 1.98551209623809 -0.492615399869623 6.79908025858852e-05 577.634626989071 214.971174932338 2.68703293439634 0.00758806923684266 -593.517397841646 353.947197228787 -1.6768529387676 0.0945539234326279 CIRBP other 0.597027237506658 1 1 2.68703293439634 -1.6768529387676 0.00200759132372973 231.793684745949 200.914185688184 1.15369496659479 0.249491605178775 -758.566838080285 330.9496466024 -2.29209139779388 0.0225533679810586 ATP5D other 1 1 1 1.15369496659479 -2.29209139779388 4.96506894971452e-06 19.724125511227 5.38129814003424 3.66530993042165 0.000289388169235595 -9.54060562224905 8.86417607401039 -1.07631048194337 0.2826042935584 CBARP other 0.0486973962588 1 1 3.66530993042165 -1.07631048194337 0.000132839449200827 100.480117304674 205.798900042521 0.488244190245493 0.625712322097741 -1411.32655489703 385.647782552589 -3.65962574854058 0.00029547379434544 HNRNPM essential 1 1 1 0.488244190245493 -3.65962574854058 0.000864917917934727 27.5777424014164 21.3664788374638 1.29070131822852 0.197739008085318 -108.631164676099 39.8486004036578 -2.72609736792983 0.00676180227548455 MARCH2 other 1 1 1 1.29070131822852 -2.72609736792983 0.00264883384126403 62.516916345331 120.703338352491 0.517938585615275 0.604862395646361 -951.216767193248 297.987656152763 -3.19213480005899 0.00155387128894472 NDUFB7 essential 1 1 1 0.517938585615275 -3.19213480005899 3.2122884756981e-05 52.3299761044294 128.061635429485 0.408631171458404 0.683084527262657 -849.338606157555 222.269608957885 -3.82120889193846 0.000159632870825123 TIMM13 essential 0.292478865712312 1 1 0.408631171458404 -3.82120889193846 2.10311895576938e-07 277.52103693686 75.0644853226321 3.69710170853842 0.000256773344850249 -222.074475063531 122.241835603794 -1.81668144924877 0.0702072123849181 CDC34 other 0.00227999125994958 1 1 3.69710170853842 -1.81668144924877 1.03022126721713e-27 666.597880676063 54.2469675191102 12.288205427174 3.73952952302134e-28 -18.3025686196193 135.848093833198 -0.134728196054722 0.892921544729841 MTAP other 1.54904069738768e-23 1 5.66463932147273e-24 12.288205427174 -0.134728196054722 0.17724212726415 70.8583478865764 113.462769641013 0.624507475983236 0.532742157319325 -220.05486962701 184.773094413345 -1.19094649751732 0.234562778975859 MISP other 1 1 1 0.624507475983236 -1.19094649751732 6.31138905271168e-19 711.915641262463 88.0076133166366 8.08925062768275 1.39531480109095e-14 -784.476892438464 259.952554385018 -3.01776950911038 0.00275898991003383 CEP170B other 9.07830201342047e-15 1 2.00255580252573e-10 8.08925062768275 -3.01776950911038 1.47737413294256e-18 501.67187978267 129.569870831597 3.87182511306734 0.000131129559644396 -1202.16445192014 212.620386791324 -5.65404131777827 3.48996889205069e-08 POLR2E essential 2.1169293950934e-14 0.000528800086523521 1 3.87182511306734 -5.65404131777827 3.14970510065974e-13 202.486926403556 46.1185190606453 4.39057737602736 1.54093029911437e-05 -258.636187864635 75.1035912798311 -3.44372597178441 0.000650633622312612 POLRMT essential 4.19162754795798e-09 1 0.170673439929907 4.39057737602736 -3.44372597178441 0.00321938896332119 11.770293870125 3.5668041687679 3.29995517365083 0.00107679881649859 5.34761266306209 5.80850833727083 0.92065162905055 0.357930217105052 HCN2 other 1 1 1 3.29995517365083 0.92065162905055 0.423286361330776 2.6796415282608 8.20680584653647 0.326514551260121 0.744249871745664 -13.3873144357511 14.0784960704118 -0.950905151288611 0.342374678489887 IZUMO4 other 1 1 1 0.326514551260121 -0.950905151288611 6.6026378808634e-08 38.4412356334402 46.322319769058 0.829864217187108 0.407234207732819 -367.923177297214 87.2315000493308 -4.21777886530837 3.21571232416301e-05 RASSF7 other 0.000735005648897714 0.466857115221986 1 0.829864217187108 -4.21777886530837 0.461342593257279 85.0640004957531 73.5969036287762 1.15580950150861 0.248624009899383 20.2953122052637 127.738139023585 0.158882165971718 0.87386225105746 GADD45B other 1 1 1 1.15580950150861 0.158882165971718 0.042328649915828 145.671338298462 57.7956642203954 2.52045443656406 0.0122094090763744 136.507331130297 94.1197165860208 1.45035850172302 0.147944178981912 PALM other 1 1 1 2.52045443656406 1.45035850172302 0.00957066263769095 560.992582196646 455.387453783577 1.23190170817323 0.218895940542011 -1444.03414445828 784.104111785338 -1.84163572509566 0.066459582315094 MKNK2 other 1 1 1 1.23190170817323 -1.84163572509566 0.0970705585772578 25.0129796839731 16.391296948091 1.52599149189877 0.128025027386912 -80.6562108101325 66.7843593025321 -1.20771108164355 0.228073099938403 ARVCF other 1 1 1 1.52599149189877 -1.20771108164355 1.09486268643368e-11 157.735496835224 23.0051658881322 6.85652507798675 3.80621032216705e-11 -129.591401618759 93.5286990855992 -1.38557900287007 0.166868335370119 TRMT2A other 1.40646060699271e-07 1 5.21184379414334e-07 6.85652507798675 -1.38557900287007 4.33213792357189e-08 349.048694098013 58.8992743492132 5.92619684970153 8.22337648035728e-09 82.1786352131075 239.458064930084 0.343185915400685 0.731690465820641 RANBP1 other 0.00048693230260948 1 0.000106517395550068 5.92619684970153 0.343185915400685 3.96667449696505e-22 325.206489587441 31.1207486290671 10.4498286163879 4.26660640240694e-22 -64.4471754774999 126.245790198737 -0.510489699308361 0.61007173698626 ZDHHC8 other 5.8341848501362e-18 1 6.38369649928127e-18 10.4498286163879 -0.510489699308361 0.00742822331121885 41.1716957825393 16.3253262110152 2.52195241003879 0.0121778735754103 -92.592642136972 67.3411722134349 -1.37497817595904 0.170144108528793 KLHL22 other 1 1 1 2.52195241003879 -1.37497817595904 8.47758086302238e-13 583.720499975255 83.0420248413565 7.02921805062431 1.37234638943413e-11 -670.139312160114 337.683265095352 -1.98452035214386 0.048096664300681 MED15 other 1.11870157068443e-08 1 1.89411248669699e-07 7.02921805062431 -1.98452035214386 8.941388071744e-23 190.079579850601 18.7450038132258 10.1402796043438 5.3711441994084e-21 -171.593135777956 77.8851493872235 -2.20315602047371 0.0283361385917081 SNAP29 other 1.32028536267372e-18 1 8.00622754363816e-17 10.1402796043438 -2.20315602047371 4.61903384898092e-19 852.094748826748 91.5244693468618 9.31002118785804 2.6871309775197e-18 -544.495652717223 380.28250293751 -1.43181884128573 0.153226381565811 CRKL other 6.65187064591742e-15 1 3.95599422510451e-14 9.31002118785804 -1.43181884128573 4.59991811398621e-18 270.870868804448 29.0285748868586 9.33118039243024 2.33633675977562e-18 -30.2156039311686 120.576528779675 -0.250592749990179 0.802299386405503 LZTR1 other 6.56086320597853e-14 1 3.44072314612156e-14 9.33118039243024 -0.250592749990179 0.00458056480885418 1949.67638847748 590.882843872621 3.29959891151921 0.00107812078831477 737.700228768519 1792.35518446068 0.411581496326295 0.680923458230713 MMP11 other 1 1 1 3.29959891151921 0.411581496326295 0.393991159104544 30.7416975110467 25.7751403028285 1.19268788258247 0.2339007969338 -22.9986751967975 78.2844547456034 -0.293783424455532 0.76911936359973 CECR2 other 1 1 1 1.19268788258247 -0.293783424455532 8.26473476468589e-16 452.525728383553 53.016605308687 8.5355470375506 5.817643844391e-16 -65.7811745070103 160.817983417396 -0.409041160131192 0.682784801911528 SMARCB1 other 1.14962460576781e-11 1 8.44140121821134e-12 8.5355470375506 -0.409041160131192 0.0487526737378129 5.22650710317485 3.26235497952329 1.60206572735949 0.110186484770443 29.1718405755502 13.550904259378 2.15275969907039 0.0321294439465847 P2RX6 other 1 1 1 1.60206572735949 2.15275969907039 0.015817498100378 -130.905880816764 46.8502652152292 -2.79413318612787 0.00551966367351555 -187.855105634629 142.113308285485 -1.32186849986812 0.187162042965807 DERL3 other 1 1 1 -2.79413318612787 -1.32186849986812 0.000270738926645201 30.9760403876913 7.681946090893 4.03231681414865 6.99983823967659e-05 -0.0133771202409261 31.9774043246085 -0.000418330396836858 0.999666496837391 SLC7A4 other 1 1 0.737432958549929 4.03231681414865 -0.000418330396836858 1.69746922506516e-11 282.379649990876 49.954338530974 5.65275526200368 3.57361584843186e-08 -428.752512264069 151.729683332692 -2.82576555125315 0.00502192342737928 BCL2L13 other 2.17089339193583e-07 1 0.000452669919520863 5.65275526200368 -2.82576555125315 0.0287668340426686 105.001292453508 40.0272098897644 2.62324785421425 0.00912798201155054 -2.49210167300933 119.861891626341 -0.0207914428780937 0.983425022469217 DDTL other 1 1 1 2.62324785421425 -0.0207914428780937 0.072255772824924 11.7506282760106 5.69814158640929 2.06218608257071 0.039999496504319 23.9839981946681 17.0631435761499 1.40560255427915 0.160815363670553 GSTT2 other 1 1 1 2.06218608257071 1.40560255427915 0.922753254721817 -6.15166056402157 16.8191700997568 -0.365752919290026 0.714793401021365 3.43605597588672 46.7720277955391 0.0734639086187842 0.941483295921247 OSM other 1 1 1 -0.365752919290026 0.0734639086187842 2.29022151496113e-06 208.606470581567 50.4670550679393 4.13351780286641 4.5711393534875e-05 -346.169313029108 151.12411536835 -2.29062921020484 0.0226368666964249 CABIN1 other 0.0230419186620239 1 0.489614736152046 4.13351780286641 -2.29062921020484 2.94520667546606e-12 211.157131326726 30.7748951772595 6.86134364099331 3.57291952101123e-11 -133.40515713041 85.8835785773824 -1.55332555233723 0.121340010717678 TBC1D10A other 3.83701525679718e-08 1 4.89632891159379e-07 6.86134364099331 -1.55332555233723 0.0169946559601061 181.625048655962 170.677744690533 1.06414019581334 0.288070027189083 1443.92249867866 511.096261604692 2.82514783838405 0.00502359475762378 SUSD2 other 1 1 1 1.06414019581334 2.82514783838405 1.3100718878441e-05 349.970609924968 89.1116594556964 3.9273268174179 0.000105371035705507 -446.460887243051 248.684135654812 -1.79529299714865 0.0735564265366833 SF3A1 essential 0.123801793401268 1 1 3.9273268174179 -1.79529299714865 0.104798633235067 85.7465279483626 40.3275955770527 2.12624945081413 0.0342500515160528 67.9042205031498 120.761399655879 0.562300707814328 0.574306060454201 GGT5 other 1 1 1 2.12624945081413 0.562300707814328 0.00651822375183558 42.2124171794201 13.9519820440351 3.02554984992022 0.00268493922720054 -11.3272228445168 38.9301409448305 -0.290962800791528 0.771270046183279 RNF215 other 1 1 1 3.02554984992022 -0.290962800791528 0.133441021514917 144.9561832717 81.4277536540759 1.78018153230049 0.0760040142239818 -111.952109373801 227.207425910455 -0.492730855627593 0.622543883119195 SEC14L2 other 1 1 1 1.78018153230049 -0.492730855627593 1.15379780788223e-11 250.4577439506 38.9317214039 6.43325635032184 4.56845517681924e-10 -268.678866333637 116.581440090193 -2.30464528595439 0.0218283128309001 SPECC1L other 1.48147638532078e-07 1 6.12995315625605e-06 6.43325635032184 -2.30464528595439 1.57037432837939e-06 116.118878252978 28.9493721309738 4.01110178582213 7.54376746658624e-05 -249.819407365124 95.3098294251878 -2.62112951908298 0.00918634322789332 PPIL2 other 0.0160131070264846 1 0.792171021666221 4.01110178582213 -2.62112951908298 0.0412650481558697 -24.4968778457137 10.1591429147877 -2.41131343964617 0.016461683005941 -37.8822037205672 30.4195759013555 -1.24532320382807 0.213929806253357 UPB1 other 1 1 1 -2.41131343964617 -1.24532320382807 0.445647736508413 -8.42278231511568 14.6667397713731 -0.574277749957457 0.566187135882316 -59.0897905018392 48.2872118783381 -1.22371510392273 0.221968504639255 YPEL1 other 1 1 1 -0.574277749957457 -1.22371510392273 0.000117932181847982 304.059545336283 77.8073346126163 3.90785196344433 0.000113807953410915 -240.549758249859 232.978917688561 -1.03249581823287 0.302624497037995 SNRPD3 essential 1 1 1 3.90785196344433 -1.03249581823287 2.64255413732712e-08 676.892765493851 116.472635062924 5.81160343052392 1.50742687551636e-08 -110.53516011723 324.992971242676 -0.340115540636391 0.73399477620959 PES1 essential 0.000300696235286453 1 0.000193764650578873 5.81160343052392 -0.340115540636391 6.51654898452277e-17 717.875374452347 86.0974190862628 8.33794301932665 2.33614312282077e-15 -617.044857927656 283.457972419404 -2.17684777979953 0.0302294973315334 MAPK1 other 9.17464931530961e-13 1 3.37525958385145e-11 8.33794301932665 -2.17684777979953 0.000169233111587705 116.631343735058 29.7806223779621 3.91635011031086 0.000110118637997943 -80.6742054779815 98.0465492024482 -0.822815347752872 0.411231526910454 PPM1F other 1 1 1 3.91635011031086 -0.822815347752872 1.27198308534767e-07 59.8402445873162 10.5857885264221 5.65288494456083 3.51970564803305e-08 5.01130748339005 29.5374691599441 0.169659338660805 0.86538627081442 SLC35E4 other 0.00139511104800932 1 0.000445981902662267 5.65288494456083 0.169659338660805 2.22211279242592e-10 65.1636162173128 9.94577530549502 6.55188903989315 2.2875996564442e-10 -30.2733187730096 32.7521282824736 -0.924316078390836 0.356022620133931 TOP3B other 2.75430880621193e-06 1 3.08642945647452e-06 6.55188903989315 -0.924316078390836 0.116176831799229 -37.9495056921879 21.2173978276735 -1.78860320197658 0.0746245938472284 -79.7672948903658 54.8408598546094 -1.45452305273549 0.146781497128059 CYTH4 other 1 1 1 -1.78860320197658 -1.45452305273549 0.099846672457188 22.231156973703 13.7590282589095 1.61575051343524 0.107143027230193 -42.3951085688924 40.5678786040993 -1.04504129936458 0.296800110843197 CRYBB2P1 other 1 1 1 1.61575051343524 -1.04504129936458 0.303012097168806 -5.67297374324761 19.8862962388886 -0.28527050362218 0.775621458434162 -79.4744256825659 51.4003457880074 -1.54618465039799 0.123048336864233 MFNG other 1 1 1 -0.28527050362218 -1.54618465039799 5.34427751177718e-05 344.146389500437 89.377357626802 3.85048740126589 0.000142371889160583 -316.852847662726 231.014716488643 -1.3715699695621 0.171158264276677 CARD10 other 0.475106270796991 1 1 3.85048740126589 -1.3715699695621 0.368312104193332 6.0867266059387 4.38400853149627 1.38839296552676 0.165989196505405 0.350920214294154 12.9291534560106 0.0271417781131692 0.978363677612307 LRP5L other 1 1 1 1.38839296552676 0.0271417781131692 1.23569107646772e-19 600.429754280659 60.9220572365618 9.85570385368269 3.71379114278333e-20 124.465361701368 228.311628319484 0.545155595523146 0.58603106594572 SLC25A1 other 1.78940424783291e-15 1 5.51980777551886e-16 9.85570385368269 0.545155595523146 0.0115891485197677 51.4044803196623 24.5789224667368 2.09140495842441 0.0372849298260033 -122.301682621333 73.5841886172815 -1.66206470329429 0.0974851839244175 GRK3 other 1 1 1 2.09140495842441 -1.66206470329429 0.156445756665139 12.4643961585733 31.8528323953848 0.391312019096278 0.695829506430153 -156.912222447388 89.4501988423387 -1.75418528385784 0.080365019564793 PLA2G3 other 1 1 1 0.391312019096278 -1.75418528385784 0.0343149080950634 -14.7393235526364 6.92609038012081 -2.1280870944077 0.0340937826664869 -35.2384652794846 17.9019479656055 -1.96841513265412 0.0498831882216203 LGALS2 other 1 1 1 -2.1280870944077 -1.96841513265412 1.43287057489286e-07 125.745750469338 30.6764535520377 4.09909673085352 5.2632344263978e-05 -235.333266222866 79.2897933925481 -2.96801462273685 0.00322338805374349 GGA1 other 0.00156784698304777 1 0.560429201722837 4.09909673085352 -2.96801462273685 2.49142100358466e-14 196.216814370801 25.8319735575505 7.59588940944265 3.48828837866383e-13 -160.876945199641 97.9695807542279 -1.64211119371049 0.101561706545681 HIRA other 3.38633942807227e-10 1 4.92441670415973e-09 7.59588940944265 -1.64211119371049 0.000197140702449889 195.511699446208 86.2546483816372 2.26668015132539 0.024076934608862 -644.627934339817 222.943412859816 -2.89144194067376 0.00409719249335524 SH3BP1 other 1 1 1 2.26668015132539 -2.89144194067376 0.856208869504582 1.84164394234515 6.41761525643338 0.286967022602201 0.774323876149982 9.84808095423603 18.6308700295593 0.528589429189902 0.59745785401827 SEZ6L other 1 1 1 0.286967022602201 0.528589429189902 0.0073950102869159 2246.49115710648 721.327920931159 3.1143826433427 0.00200997323332805 2294.88226035027 1864.42483391659 1.23087947478656 0.219271881829873 LGALS1 other 1 1 1 3.1143826433427 1.23087947478656 2.44148644269405e-17 201.520841449162 24.1124126518646 8.35755610020129 2.00047493082107e-15 -151.824994898622 70.0003363033726 -2.16891807834511 0.0308273355485694 HPS4 other 3.4561682082777e-13 1 2.89248670247419e-11 8.35755610020129 -2.16891807834511 0.0109751415614789 -29.1302771150025 56.3098095614578 -0.517321534948703 0.605292503000154 -477.672524463779 158.131107448279 -3.02073723615711 0.00272674974837606 PIK3IP1 other 1 1 1 -0.517321534948703 -3.02073723615711 0.000393005818012652 39.4335259926684 13.2419651884318 2.97792098314211 0.00312376150640716 -65.4707494234601 34.2266645041284 -1.91285801207895 0.0566585976592917 NOL12 essential 1 1 1 2.97792098314211 -1.91285801207895 3.01150358233517e-16 251.656310868717 29.6723175435124 8.48118150864625 8.43793804327642e-16 -82.4672236444247 86.1412019168356 -0.957349349780864 0.33911592921894 SRRD other 4.21068430882103e-12 1 1.22282598123162e-11 8.48118150864625 -0.957349349780864 0.010826163288935 49.3340939476889 36.4096930710794 1.35497143168382 0.176391446051388 -238.598808761223 102.246928768208 -2.33355477407173 0.0202439104506622 PATZ1 other 1 1 1 1.35497143168382 -2.33355477407173 0.0159755215752531 131.795634899883 65.1418738290473 2.02320914571412 0.0438826345109546 -259.239299366721 168.372974025399 -1.53967286535911 0.12462834299544 TRIOBP other 1 1 1 2.02320914571412 -1.53967286535911 1.56858525487565e-25 346.637027658744 31.3103344420963 11.0710100621824 2.52450288964873e-24 -123.386487376408 90.8965009998004 -1.35743935156182 0.175601192671588 TFIP11 essential 2.34299579520776e-21 1 3.79887194834341e-20 11.0710100621824 -1.35743935156182 5.16185597982225e-05 153.192347968645 34.4453577347183 4.4474018574131 1.20057692369879e-05 26.433228571279 89.0313247418004 0.296898070964775 0.766736949336629 GCAT other 0.460127842041355 1 0.133948367377074 4.4474018574131 0.296898070964775 0.387475150207147 2.4344466249278 5.39939014307507 0.450874369219285 0.652385455794652 -20.8670591536724 17.4662380800689 -1.19470827421528 0.233085766550822 GGTLC2 other 1 1 1 0.450874369219285 -1.19470827421528 0.00264843776870226 507.572168921734 201.239412608954 2.5222304236598 0.012147623407434 -914.91714494487 524.955529191821 -1.74284695382369 0.0823239375751595 EIF3L essential 1 1 1 2.5222304236598 -1.74284695382369 9.96195572767987e-05 325.020380979841 85.1932158311651 3.81509698640749 0.000163458027486941 -260.991161869422 221.770242538783 -1.17685384153277 0.240131224261836 SNU13 other 0.859019442397835 1 1 3.81509698640749 -1.17685384153277 1.83111366665587e-06 793.553006240396 175.412258945518 4.5239312862784 8.59228033780817e-06 -724.440765976654 466.430798716028 -1.55315808469523 0.121383139763263 MICALL1 other 0.0185473503295573 1 0.0969638836121652 4.5239312862784 -1.55315808469523 0.00138555939400557 155.999118326474 44.4751699585865 3.50755530494283 0.000517578776796386 -27.582929174563 118.261911519296 -0.233235949091374 0.815728724488207 POLR2F essential 1 1 1 3.50755530494283 -0.233235949091374 0.426281932091116 -64.5297259943708 65.1275757778178 -0.990820328005351 0.32252900412569 -183.207756764637 173.177789118612 -1.05791717111688 0.290898693246575 SOX10 other 1 1 1 -0.990820328005351 -1.05791717111688 6.23969977358702e-07 24.1484691020626 5.06726403938117 4.76558334327723 2.8654305574182e-06 -20.0978156097127 13.1908199973186 -1.52362139835113 0.128594024264279 CCDC134 other 0.00655355667219845 1 0.0332819759244124 4.76558334327723 -1.52362139835113 0.000552417393591591 19.6561724605757 12.5422638143348 1.5671949459483 0.11805743240535 -111.908600847033 35.5979051381708 -3.14368501215641 0.00182465902976627 DEPDC5 other 1 1 1 1.5671949459483 -3.14368501215641 0.00627327061319241 45.8596015508482 20.3278924751649 2.25599390624857 0.0247522388061299 -92.1910070702088 54.0529788533745 -1.70556755660569 0.0890681887183794 PICK1 other 1 1 1 2.25599390624857 -1.70556755660569 0.146611995899336 50.8942668328522 26.9675487161353 1.88724111963506 0.0600413494045476 -8.24480985392387 77.7488063843394 -0.106044198455818 0.915614357778879 TTC28 other 1 1 1 1.88724111963506 -0.106044198455818 0.329854736447413 7.91708063738407 5.78787109463202 1.36787438903517 0.172320277230926 -4.09341534252105 15.3902660724136 -0.265974306308994 0.790431900159953 SLC16A8 other 1 1 1 1.36787438903517 -0.265974306308994 0.581837092093907 -25.7013286447363 30.1794785000285 -0.851616062375366 0.395066069600624 -61.1238355118733 78.5615403920099 -0.778037640388349 0.437123495287659 CENPM other 1 1 1 -0.851616062375366 -0.778037640388349 0.980519233397755 1.09668246247447 17.9311036794504 0.0611609013075589 0.951269367861712 -7.92581542027442 46.6772520931775 -0.169800385945018 0.865274754404906 SEPT3 other 1 1 1 0.0611609013075589 -0.169800385945018 0.00448651401733968 134.154662674962 47.3857375000438 2.83111901919513 0.0049321112495632 -139.977060240612 134.491907792667 -1.04078425637623 0.298761393240545 SLC5A1 other 1 1 1 2.83111901919513 -1.04078425637623 0.171505167642223 19.6171083975539 19.2534228577544 1.01888939657569 0.309055135760842 106.607375573384 59.0167923798164 1.80639054198824 0.0718333327827678 TPTEP1 other 1 1 1 1.01888939657569 1.80639054198824 0.00168389821614708 175.497685996225 49.8939195178056 3.51741630427721 0.000499423633999071 -0.442332934156821 137.211580654819 -0.00322372887219769 0.997429868687419 KDELR3 other 1 1 1 3.51741630427721 -0.00322372887219769 0.226228979912542 -4.37548578377292 3.31240479373549 -1.32093933448229 0.187468366169633 -11.9499005449136 8.62266798273179 -1.38587042535386 0.166754515874768 CYP2D6 other 1 1 1 -1.32093933448229 -1.38587042535386 0.00504792054813675 532.42906990122 225.348016639443 2.36269694245016 0.0187461158756545 -1044.93998493936 619.721959295899 -1.68614322804791 0.0927521214237745 DDX17 other 1 1 1 2.36269694245016 -1.68614322804791 0.821700569541831 -2.1734894915467 3.61689655592995 -0.600926639160647 0.548318274261066 -3.07267148467527 9.94670489511275 -0.308913506239137 0.757590246976868 DMC1 other 1 1 1 -0.600926639160647 -0.308913506239137 6.34305912786091e-07 278.02105898773 79.6173883929998 3.49196406211403 0.000547105102474498 -683.229902829319 207.25555857889 -3.29655767745913 0.00108910930031094 TCF20 other 0.0066583091665156 1 1 3.49196406211403 -3.29655767745913 0.00189754376487223 31.3718249293102 11.1261456605964 2.81964894998765 0.00511121165639446 -48.043848477119 32.0696654912115 -1.49810881221337 0.135103223581699 HSCB essential 1 1 1 2.81964894998765 -1.49810881221337 0.000125540941799698 63.447176000251 17.6955821687559 3.58548113281495 0.000389470518155362 -73.3424764808318 48.6640220581534 -1.50711908672875 0.132776010575088 CBY1 other 1 1 1 3.58548113281495 -1.50711908672875 3.3253351791382e-06 307.237826972774 69.2468142969968 4.43685142907865 1.25976508602691e-05 -289.394814926231 188.580698105926 -1.5345940376341 0.12587786928778 TOMM22 essential 0.0330438556750963 1 0.140363025885118 4.43685142907865 -1.5345940376341 0.374692627908565 -1.56308710050117 2.14295286566601 -0.729408063772498 0.466287306332621 -8.41278274804298 6.35911371752355 -1.32294893938761 0.186799888258592 RSPH14 other 1 1 1 -0.729408063772498 -1.32294893938761 0.0585664480064239 176.14324456991 219.85426002187 0.801181858165443 0.423628368400248 -1275.49802402343 633.701264642734 -2.01277493858644 0.0449862310300047 XBP1 other 1 1 1 0.801181858165443 -2.01277493858644 9.3625258155605e-08 293.649755833786 68.2576341304887 4.30207931427 2.25064942850555e-05 -555.348585237872 193.731276961023 -2.86659229190754 0.00442414516031818 RTCB essential 0.00103549535520099 1 0.246491125409928 4.30207931427 -2.86659229190754 9.81783036927143e-08 339.244636484214 66.4063932286215 5.10861409557774 5.60635131701558e-07 -293.773574045884 180.845344596498 -1.62444642797608 0.105271284743392 JOSD1 other 0.00108408482937495 1 0.00676238095858419 5.10861409557774 -1.62444642797608 1.41465112332658e-07 198.427292919128 44.155559844427 4.49382350984216 9.78766734327877e-06 -304.877657426245 122.783018148559 -2.48306045920263 0.0135379068077563 FBXO7 other 0.00154819418936861 1 0.10994486726705 4.49382350984216 -2.48306045920263 9.403566823685e-05 183.064827095838 63.0246108279181 2.90465620796417 0.00393408482078654 -438.208553769033 171.635695135489 -2.5531318145862 0.0111424760760574 GTPBP1 other 0.812468173566384 1 1 2.90465620796417 -2.5531318145862 2.31825217066355e-07 195.121085217451 64.0064722121592 3.04845867103396 0.00249324528972924 -642.851711725051 165.891845326278 -3.87512544972108 0.000129444415278937 POLDIP3 other 0.00250695789735556 1 1 3.04845867103396 -3.87512544972108 0.0829527985709505 -26.1157640604446 16.2966864395316 -1.60251988386391 0.110030380172162 -88.3298970932658 47.4709889594826 -1.86071322779176 0.0637046207176318 RAB36 other 1 1 1 -1.60251988386391 -1.86071322779176 0.00335312112598583 1944.06654603359 592.799245931026 3.2794686554979 0.00115457255908667 -249.058309206717 1552.66051075066 -0.160407447398985 0.872661334282304 TIMP3 other 1 1 1 3.2794686554979 -0.160407447398985 5.12280904720912e-11 241.026080125686 35.2217111849698 6.8431110248993 3.97396560330484e-11 -24.8622683794647 99.9990330525563 -0.248625087868579 0.803810786170112 PPP6R2 other 6.47062010752984e-07 1 5.43837192812267e-07 6.8431110248993 -0.248625087868579 1.56580804653962e-12 637.265750196384 93.9291788668988 6.78453445333972 5.67093833982259e-11 -476.259242872326 266.677192734426 -1.7859016663139 0.0750649504211991 SBF1 other 2.05418357625533e-08 1 7.73629408318598e-07 6.78453445333972 -1.7859016663139 0.025375482156337 361.81997183214 158.399129529224 2.2842295466364 0.0230167366994039 -411.932850916091 431.370290882647 -0.954940244199979 0.340333265509519 SUN2 other 1 1 1 2.2842295466364 -0.954940244199979 1.6397871288751e-09 960.694013673621 160.130779635026 5.99943381193335 5.36981106182705e-09 -505.941815004884 412.802170767423 -1.22562779663757 0.221242852669049 CYB5R3 other 1.96495691653104e-05 1 7.00062268130393e-05 5.99943381193335 -1.22562779663757 0.170425047107468 17.6913978641654 18.0445646850586 0.980428077537075 0.327620156680736 -66.794422967521 49.1409841719386 -1.35924064389543 0.175033480206996 DNAL4 other 1 1 1 0.980428077537075 -1.35924064389543 8.07798185561503e-05 219.226472898664 74.2143466613122 2.95396352270182 0.00337043338801561 -507.11713067788 210.704212120317 -2.406772629625 0.0166621678461707 LMF2 other 0.702784421438508 1 1 2.95396352270182 -2.406772629625 0.00160313434798493 85.5278639792187 24.9243558218835 3.43149747140609 0.000680097877166336 -21.8261910384457 69.5232568952506 -0.313940859694344 0.753773102351067 RHBDD3 other 1 1 1 3.43149747140609 -0.313940859694344 3.42738537848219e-11 300.145531345666 52.0835749607593 5.76276746693754 1.95061661592469e-08 -390.590206425083 134.803146599253 -2.89748582491357 0.00402190365789021 PACSIN2 other 4.3500375223696e-07 1 0.000249873988499953 5.76276746693754 -2.89748582491357 0.0031965274069698 22.7732451149883 7.38805569754967 3.08244090830843 0.00223164122025688 -13.7986785819579 18.9464362760569 -0.728299421638237 0.466962922127734 TTLL1 other 1 1 1 3.08244090830843 -0.728299421638237 1.47195469253224e-11 651.836443530722 101.426480450858 6.42668897346333 4.80054384853943e-10 -546.210221932054 282.91600821133 -1.9306444530493 0.054421494889719 AP1B1 other 1.88454359284903e-07 1 6.43848940966108e-06 6.42668897346333 -1.9306444530493 0.00431954180467056 73.7922793849784 27.1867623960199 2.71427242089633 0.00700223095282698 -93.0206604666513 71.3484215550935 -1.30375218455005 0.193255210696286 HMGXB4 other 1 1 1 2.71427242089633 -1.30375218455005 5.53019204992284e-06 327.148579071883 71.4907061063689 4.57609942452 6.78644953119106e-06 -193.260399620042 187.618847814525 -1.03006921677237 0.303755434468866 TOM1 other 0.0540023253674965 1 0.0770940666743304 4.57609942452 -1.03006921677237 0.137759830963562 -144.512310018273 82.0908132127597 -1.7603956443181 0.0793020255951621 -305.611080804294 229.091042111783 -1.33401584796656 0.183153236428971 NEFH other 1 1 1 -1.7603956443181 -1.33401584796656 0.000379239086481299 83.6886303944889 22.6695986721276 3.69166792958645 0.000262353000425031 -39.3977349366062 65.2365178676012 -0.603921487909037 0.546329136488826 CHKB other 1 1 1 3.69166792958645 -0.603921487909037 0.061893333118628 26.3554517033745 24.1213302873287 1.0926201577373 0.275382488728942 -110.844918264494 61.858392233584 -1.79191398712613 0.0740914212742248 BIK other 1 1 1 1.0926201577373 -1.79191398712613 0.963099687838642 21.103835738344 147.656752801466 0.142924961696263 0.886439396577366 100.409195239478 387.507570444559 0.259115441601013 0.795712775362435 HMOX1 other 1 1 1 0.142924961696263 0.259115441601013 0.0013187592339139 51.2287270962996 16.9138588923892 3.02880184955021 0.002655089755275 -57.7391583927423 43.3750587171605 -1.33116035114205 0.184083841912123 MCAT other 1 1 1 3.02880184955021 -1.33116035114205 1.02296671766495e-13 237.020765926131 29.6432116007122 7.99578564963709 2.4100916571721e-14 46.4457284348143 82.72538632973 0.561444684581939 0.574889873005428 THOC5 essential 1.37486726854169e-09 1 3.45173327140188e-10 7.99578564963709 0.561444684581939 0.234500971307714 -88.5585740801056 167.710107203376 -0.528045539752197 0.597833703482099 -747.555535297757 440.135211890776 -1.69846791418104 0.0903915030243322 MCM5 essential 1 1 1 -0.528045539752197 -1.69846791418104 0.00133787032799117 -5.84632328360448 1.82978936930549 -3.19507992650733 0.00153724092985481 -12.7748959235489 5.1286287321003 -2.49089894996498 0.0132485550577685 APOBEC3H other 1 1 1 -3.19507992650733 -2.49089894996498 3.79432307628399e-05 188.034303797991 45.0363576385665 4.17516676874796 3.85499988115331e-05 -100.959197873955 129.601551058437 -0.778996833366853 0.436564547152809 ARSA other 0.34296886286531 1 0.415337687195458 4.17516676874796 -0.778996833366853 0.0511808104611272 216.166102174937 227.867811247613 0.948646941362154 0.343516067556233 -1155.3750089955 584.359829149546 -1.97716364363545 0.0488811210525769 TSPO other 1 1 1 0.948646941362154 -1.97716364363545 0.186740083137605 38.3025870824472 33.2018703289414 1.15362739216108 0.249513869027562 -100.27690128922 87.1343562775119 -1.15083080398105 0.250661058292584 RASD2 other 1 1 1 1.15362739216108 -1.15083080398105 3.38002057841155e-08 1162.14831579391 234.59030130213 4.95394868987859 1.18012938590355e-06 -1318.26271532405 601.59944328464 -2.19126319021597 0.0291533609483361 TTLL12 other 0.000382280327418347 1 0.0140211172339201 4.95394868987859 -2.19126319021597 0.332906249328537 -57.5187534192586 46.1890880506641 -1.24528878674043 0.213939564114141 -139.611387821852 130.694865178099 -1.06822397063268 0.286227189849379 CBX7 other 1 1 1 -1.24528878674043 -1.06822397063268 7.65039394294216e-10 208.541109339796 31.8635066966968 6.54482607093007 2.375389408687e-10 6.54884377591975 90.1597517417615 0.0726360005368821 0.942141298843019 PDGFB other 9.29522864067473e-06 1 3.20321261761442e-06 6.54482607093007 0.0726360005368821 0.0113117171498615 33.6494271992142 12.5033378693736 2.69123553652318 0.00749647289580236 -23.8767445643001 34.8879968451258 -0.684382788449945 0.494233510321092 CABP7 other 1 1 1 2.69123553652318 -0.684382788449945 0.412874228124181 167.29026518739 856.535557961139 0.195310356508259 0.845274330846291 -3006.64700987688 2423.62003651573 -1.24056038676728 0.215679816862519 RPL3 essential 1 1 1 0.195310356508259 -1.24056038676728 0.00826964465461502 70.7410127203814 27.0870057309824 2.61162172825426 0.00944009266309194 -78.7000819382855 75.5807273513089 -1.04127182545462 0.298542898608878 ZMAT5 essential 1 1 1 2.61162172825426 -1.04127182545462 3.48349298332002e-09 412.677221467828 73.4014981607731 5.62219071556185 4.10979524818077e-08 -358.899998068354 192.633494097736 -1.86312354323106 0.0633608728941713 RBFOX2 other 4.12724248663756e-05 1 0.000519354825512603 5.62219071556185 -1.86312354323106 0.12291047620307 57.440290776679 33.0577712059498 1.73757300269356 0.083251179736917 -63.5843655326986 93.5389966156285 -0.67976317721239 0.497147401560431 SYNGR1 other 1 1 1 1.73757300269356 -0.67976317721239 1.42236307633418e-06 61.9292385568817 20.3152524887657 3.04841097058126 0.00249301132588273 -203.77544457713 57.4832562653311 -3.54495304922434 0.000451446770534421 TAB1 other 0.0145635755385856 1 1 3.04841097058126 -3.54495304922434 7.20160477112521e-18 404.96126804867 44.4611832287882 9.1081981773814 9.68234863124281e-18 -44.2766844148465 124.059801984239 -0.356897912995794 0.721405688591444 ASCC2 other 1.02558053545594e-13 1 1.41991642677176e-13 9.1081981773814 -0.356897912995794 1.69660786157359e-10 299.60808979454 46.72996850869 6.41147638990649 5.22445004254457e-10 -143.006127265195 130.390381427458 -1.09675365390932 0.273581544466352 MTMR3 other 2.10786560721903e-06 1 6.99867327699271e-06 6.41147638990649 -1.09675365390932 2.58215152678472e-13 271.939264557952 38.3040719196375 7.09948710227165 8.17331838878169e-12 -211.332826645804 108.38372712226 -1.94985753172535 0.0520689193763324 MIEF1 other 3.44459013673082e-09 1 1.1324132627657e-07 7.09948710227165 -1.94985753172535 0.00935051599025032 -109.423430400027 37.2790459152307 -2.93525297425385 0.00357394139397664 -149.422180702207 97.4549639429036 -1.5332434045099 0.126203927181776 APOL4 other 1 1 1 -2.93525297425385 -1.5332434045099 0.0517107537495004 -1362.22167385756 803.970629609718 -1.69436746031237 0.0911684098077813 -4377.44776672853 2101.74179076181 -2.08277143556339 0.0380658441986343 APOL1 other 1 1 1 -1.69436746031237 -2.08277143556339 1.63676699951292e-09 27.8325854841036 4.74223363228779 5.86908778483703 1.09506142196672e-08 -17.4012884485225 12.0967193092161 -1.43851303842894 0.151265845326529 PNPLA3 other 1.96150157221628e-05 1 0.000141350528347464 5.86908778483703 -1.43851303842894 2.61623419846948e-14 14791.5798172958 1918.14467109438 7.71139947898539 1.59952860026283e-13 -6959.47493221167 5013.09875419564 -1.38825809613007 0.166027165788179 MYH9 other 3.55415415862078e-10 1 2.26925122519288e-09 7.71139947898539 -1.38825809613007 0.148844063174507 5.53291517886025 2.94418438832693 1.87926924712905 0.0611192121604793 -0.95413075832534 8.33075078836327 -0.114531184831277 0.9088887801237 CACNA1I other 1 1 1 1.87926924712905 -0.114531184831277 1.12296030064559e-08 178.477281319055 34.2175085907824 5.21596365923422 3.29108449816549e-07 -177.97376789999 87.2836787426891 -2.03902688868848 0.042268740481519 SAMM50 essential 0.00012997142519672 1 0.0040091991356652 5.21596365923422 -2.03902688868848 0.000283361694934115 183.876660288428 58.8937198384516 3.12217772612786 0.00195905107678417 -296.327047285015 153.960092121747 -1.92470037657997 0.0551531972776301 TXN2 other 1 1 1 3.12217772612786 -1.92470037657997 0.095539790657562 -100.546772160284 98.2604214954799 -1.0232682765859 0.306953946975707 -537.616587928875 256.872610303156 -2.09293076165026 0.0371425254056135 FOXRED2 other 1 1 1 -1.0232682765859 -2.09293076165026 0.000229173963207909 -21.5650879742107 5.78757979587416 -3.72609773598007 0.000229957530136822 -42.7536427970564 16.3763129572848 -2.61070015629115 0.0094623015184503 GRAP2 other 1 1 1 -3.72609773598007 -2.61070015629115 2.71867826913334e-13 1016.8015821311 143.079962145718 7.10652677623406 7.77986427643914e-12 -749.466829059094 374.039952191106 -2.0037079586519 0.0459440247664875 EIF3D essential 3.62399813275474e-09 1 1.07828918871447e-07 7.10652677623406 -2.0037079586519 8.15549058693493e-06 136.576757278241 37.8548411086738 3.60790729212561 0.000358203472143689 -264.537716847165 107.11260091582 -2.46971611729478 0.0140450699220496 TNRC6B other 0.0784721304274879 1 1 3.60790729212561 -2.46971611729478 0.000125893901603472 128.621423235074 43.4566371059763 2.95976476323765 0.00330930023899446 -292.202718935486 122.963227189706 -2.3763423066693 0.0180751721193 SGSM3 other 1 1 1 2.95976476323765 -2.3763423066693 0.128698164594734 48.6828017225602 24.4972020192649 1.98728008546754 0.0477435883920254 3.50275327228902 63.3182086549897 0.055319841585774 0.955918177617228 IFT27 other 1 1 1 1.98728008546754 0.055319841585774 5.78876964126374e-15 1053.49079510902 138.866112561278 7.58637781153515 3.6366935052679e-13 -678.670227287501 346.732566001895 -1.95733050146721 0.0511803676090489 KIAA0930 other 7.95492724102463e-11 1 5.13246554398459e-09 7.58637781153515 -1.95733050146721 0.0169943593142523 -41.7313729232797 15.9974906479535 -2.60861992931488 0.00951742494326823 -73.6452462256899 41.3489038465202 -1.78106888876784 0.0758496706489833 NCF4 other 1 1 1 -2.60861992931488 -1.78106888876784 0.0400224377874275 -200.245195500636 94.6969069779996 -2.11459066500617 0.0352377828558291 -460.214119868011 244.764218799346 -1.88023446452068 0.0609843041125608 CSF2RB other 1 1 1 -2.11459066500617 -1.88023446452068 7.96288881041507e-07 71.7876958081736 17.2642041822013 4.15818157909554 4.13052570148499e-05 -109.58571803623 45.1093893891207 -2.42933277351476 0.0156801719599155 SLC25A17 other 0.00830131158485771 1 0.443866291881577 4.15818157909554 -2.42933277351476 0.00856653516047813 49.7473006449561 18.7447685708308 2.65392983951635 0.00835469144849628 -43.5424388841069 46.8035115680784 -0.930324187764669 0.352906742581019 FAM118A other 1 1 1 2.65392983951635 -0.930324187764669 0.0251074636800856 45.7795486516026 18.6547807343128 2.45403842069276 0.0146586637147122 -28.4099421106852 48.2172330545913 -0.589207225527015 0.556137993231367 KCTD17 other 1 1 1 2.45403842069276 -0.589207225527015 1.00033784950437e-10 527.402092093218 81.8893652452004 6.44042227600647 4.39818321980256e-10 -275.974638179416 213.967537958223 -1.28979676456014 0.198058442848186 ST13 other 1.25132261594501e-06 1 5.90368133594098e-06 6.44042227600647 -1.28979676456014 0.000437791476142231 -152.378681488493 44.934259185948 -3.39114707239116 0.000783264862450988 -327.62205127937 116.142112746418 -2.82087214992112 0.00508840666104315 IL2RB other 1 1 1 -3.39114707239116 -2.82087214992112 0.0600059035004719 123.232039544326 59.0351535870372 2.08743489356119 0.0376445882754098 -98.6699900402975 154.252098891977 -0.639667082322141 0.522849610881963 RBX1 essential 1 1 1 2.08743489356119 -0.639667082322141 0.000184910858478822 51.507855246763 24.6213809764504 2.09199700439341 0.0372315474610923 -197.426783682756 64.3328502167293 -3.06883315472033 0.0023339228328287 L3MBTL2 other 1 1 1 2.09199700439341 -3.06883315472033 0.161790713159173 -0.489977094072664 7.6005304338568 -0.064466170925393 0.948639548030547 -37.2738209837185 19.8593160325443 -1.87689349032144 0.0614481442121781 CHADL other 1 1 1 -0.064466170925393 -1.87689349032144 0.000492758225088361 509.688441188438 243.424619606894 2.09382453595505 0.0370671785575376 -1768.37118437118 636.040667548791 -2.78028005848467 0.00575478431943174 RANGAP1 essential 1 1 1 2.09382453595505 -2.78028005848467 3.52454247403742e-09 466.051202873728 93.2836502296725 4.9960652453701 9.67387953609984e-07 -683.171029766592 243.739500381204 -2.80287367742251 0.00537583380586398 ZC3H7B other 4.17446810624992e-05 1 0.0115419056745207 4.9960652453701 -2.80287367742251 0.00139628677337326 86.5345369055726 27.8834173429136 3.10344086742886 0.0020846110278453 -86.6367550541113 72.8543924048987 -1.18917682509265 0.235257283881055 PHF5A essential 1 1 1 3.10344086742886 -1.18917682509265 0.00796796687221086 284.481073046228 135.209577414687 2.10400090352865 0.0361632212955864 -629.015824433332 353.278491252565 -1.78050982442528 0.0759471951492545 ACO2 essential 1 1 1 2.10400090352865 -1.78050982442528 6.27868769636494e-07 360.09637474157 75.0764504012034 4.79639584473213 2.48680769455241e-06 -286.611953631731 196.16136396159 -1.46110298095119 0.144974547402363 POLR3H essential 0.00659324994995282 1 0.0290011513338702 4.79639584473213 -1.46110298095119 0.001883406539095 92.3322880987982 27.952190911452 3.30322186161692 0.00106474725287709 -37.8475578002327 70.8296613698996 -0.534346163291369 0.593475426666499 TRMU other 1 1 1 3.30322186161692 -0.534346163291369 0.000402119344897387 98.3092280994441 26.8907148287428 3.65588005843429 0.000299644780872153 -52.9652609849192 70.2792709219837 -0.753639875457949 0.451621378072104 PMM1 other 1 1 1 3.65588005843429 -0.753639875457949 6.58203329501333e-05 182.250044057856 44.5799099020749 4.08816537445207 5.50837916006361e-05 -92.1587008910394 116.510237293384 -0.790992302753404 0.429536171713286 DESI1 other 0.578758187630522 1 0.585100034381957 4.08816537445207 -0.790992302753404 0.00037743078607404 188.226336751727 55.0715183411125 3.41785268359327 0.000713288468065412 -162.324150778903 137.286521838328 -1.18237499650592 0.237940258961652 CERK other 1 1 1 3.41785268359327 -1.18237499650592 1.01368595694501e-10 189.993467018122 31.8538582520235 5.96453545799441 6.52942759727412e-09 -194.355504172745 89.9667949811111 -2.16030263402793 0.0314959744155745 BRD1 other 1.26741155196835e-06 1 8.491520590255e-05 5.96453545799441 -2.16030263402793 1.24693590322278e-14 217.3300001165 28.2557378382207 7.69153512680615 1.83658608202882e-13 -110.964288626805 79.8160559294875 -1.39025021137144 0.165425195068167 ZBED4 other 1.70418729893457e-10 1 2.60336077127585e-09 7.69153512680615 -1.39025021137144 0.130327801871285 7.34359950722363 3.63480858901731 2.02035384460479 0.0441847099385232 6.79303393437115 10.826244648816 0.627459858401967 0.53080811591712 MLC1 other 1 1 1 2.02035384460479 0.627459858401967 6.22798163098278e-09 120.59105784743 21.0313974675535 5.73385853381704 2.27175230624707e-08 -64.6076212554624 59.4122944266144 -1.08744531546859 0.27765843957674 HDAC10 other 7.29857167334871e-05 1 0.000290011899415501 5.73385853381704 -1.08744531546859 6.42508067365691e-06 44.1859637260361 10.8095066640367 4.08769475789707 5.5269710765536e-05 -48.7123352262378 31.536868554486 -1.54461547575904 0.12343698150343 KCNK10 other 0.062361833018514 1 0.586909058619227 4.08769475789707 -1.54461547575904 5.69323303303642e-05 282.19550410252 62.8909706110945 4.48705913361653 1.00844381132181e-05 145.387844284854 172.379793822017 0.843415814935755 0.399625935921802 ABHD4 other 0.504648176048348 1 0.113167564506534 4.48705913361653 0.843415814935755 1.55631758352783e-20 528.919464337349 58.8984042704371 8.98020024292628 2.36884178257423e-17 -425.789529057025 159.978073753244 -2.66154929277232 0.00817077551059388 KHNYN other 2.267087823925e-16 1 3.46656306461913e-13 8.98020024292628 -2.66154929277232 8.54984194197615e-09 274.731678124757 47.017461753067 5.84318395509378 1.31757963089309e-08 -143.821250528295 140.331927489994 -1.0248647838073 0.306241805008459 FKBP3 other 9.96142084659641e-05 1 0.000169612025884868 5.84318395509378 -1.0248647838073 3.15544293550624e-10 157.554738946624 29.1543563898192 5.40415767852941 1.27432141771675e-07 -221.003494788772 79.6347815542878 -2.77521317287864 0.00584095535468621 SDR39U1 other 3.88939896230499e-06 1 0.00157952139725991 5.40415767852941 -2.77521317287864 0.866857758292855 1.92791262644239 6.75730923167834 0.285307740158511 0.775594118885343 -6.8100309256041 18.362020897022 -0.370875894532316 0.710976910422409 CTSG other 1 1 1 0.285307740158511 -0.370875894532316 0.0128769776366252 -41.9445915097698 14.2225097113282 -2.94916947578955 0.00342248459180114 -40.6378667616075 38.6476349644048 -1.0514968587091 0.293828824449864 GZMH other 1 1 1 -2.94916947578955 -1.0514968587091 0.00706896825989121 -88.916897736078 28.1601906726358 -3.15753890908422 0.00174363151052001 -80.0430933981164 76.5212885583206 -1.04602385697036 0.296344454231474 GZMB other 1 1 1 -3.15753890908422 -1.04602385697036 6.43184221655734e-07 201.5400628063 43.0392953433929 4.68269894286825 4.18956096623757e-06 -195.77215270178 117.625428595538 -1.66436930380892 0.0970174791149961 RBM23 other 0.00674893203783362 1 0.0482008989165632 4.68269894286825 -1.66436930380892 8.52895906339469e-24 582.394017224152 54.2779896943415 10.7298376469692 3.79416048137e-23 -112.035292382357 148.340528118827 -0.755257472810209 0.450650033509273 PRMT5 essential 1.26484462910143e-19 1 5.69199955415127e-19 10.7298376469692 -0.755257472810209 0.600322726605328 -21.4913318799956 28.640105768388 -0.750392894977258 0.453581820621847 43.2011189982713 90.7964587759343 0.475801805276152 0.63454749291331 COCH other 1 1 1 -0.750392894977258 0.475801805276152 1.07172685664277e-40 87.8559119692723 5.81766249852327 15.1015828077984 4.36117432080985e-39 -17.4702423780327 18.4434777403127 -0.947231461659055 0.344251559891216 AP4S1 other 1.63770580963582e-36 1 6.66474659706162e-35 15.1015828077984 -0.947231461659055 0.00668321040980532 16.697146251956 8.57074268680696 1.94815628727929 0.0522841479654823 -52.8960609141736 26.1589271071967 -2.02210360912016 0.0440105852579071 POLE2 other 1 1 1 1.94815628727929 -2.02210360912016 8.77879025655526e-11 35.5384885562114 5.30862067530706 6.69448633267733 9.88338500369103e-11 -10.9646795122252 16.2968826939374 -0.67280839643671 0.50156089715682 VCPKMT other 1.10007020704894e-06 1 1.34275668660146e-06 6.69448633267733 -0.67280839643671 6.45359412768608e-11 173.910544407658 26.8852478585196 6.46862343701802 3.75961686156408e-10 -116.659720742767 82.5347594688301 -1.41346169169882 0.158504328120463 SOS2 other 8.12765644440785e-07 1 5.0514212151975e-06 6.46862343701802 -1.41346169169882 2.5731454274407e-06 18.0650354447747 3.59465624927662 5.0255251662548 8.40730404189689e-07 -0.777477867433294 11.0528974193814 -0.0703415437539459 0.943966170887964 CDKL1 other 0.0257880634738107 1 0.0100584985557254 5.0255251662548 -0.0703415437539459 1.59939485456025e-07 258.762987970337 46.5916794320321 5.55384547465862 5.92051623646671e-08 -20.3063790597346 141.615278388048 -0.143391160126749 0.886072369190711 NIN other 0.00174461990735432 1 0.000743912865112042 5.55384547465862 -0.143391160126749 5.47205390355919e-12 1378.55923936834 214.295997622035 6.43296773932183 4.61080079505738e-10 -1510.85807537082 651.352081114825 -2.31957203972529 0.0209990983352855 PYGL other 7.08630980510915e-08 1 6.18631142672848e-06 6.43296773932183 -2.31957203972529 0.197029586396174 18.2912991152787 10.9673007320248 1.66780318714773 0.0963422813627441 -10.0688289361394 33.3350796808442 -0.302049043606318 0.762812747289434 TRIM9 other 1 1 1 1.66780318714773 -0.302049043606318 6.61744904203844e-10 181.103053120448 28.6842884094061 6.3136672779047 9.22303489269238e-10 -83.0014315015277 88.430781397493 -0.938603393409354 0.348651259606529 PSMC6 essential 8.05475897396919e-06 1 1.22878493875341e-05 6.3136672779047 -0.938603393409354 4.27354073402336e-11 220.879496551155 32.4684027874382 6.80290613607306 5.14452989083783e-11 -81.5727503399708 100.096826117541 -0.814938430157441 0.415721311594969 GNPNAT1 other 5.41243933964059e-07 1 7.02176884800455e-07 6.80290613607306 -0.814938430157441 0.000140115330764929 72.6873487811637 18.0129354507925 4.03528614088082 6.84627213502755e-05 120.566618357782 54.3443608879476 2.21856723287956 0.0272265195667467 DDHD1 other 1 1 0.721939396638655 4.03528614088082 2.21856723287956 0.00770168165847097 49.5227009563759 19.8634631304517 2.49315542970224 0.0131694827349489 -77.8691735349863 59.5627204629466 -1.30734749739022 0.192039175633678 CDKN3 other 1 1 1 2.49315542970224 -1.30734749739022 1.55462379538893e-06 221.056277889748 56.1759701233916 3.93506827570923 0.000102184893726429 -429.961157127487 168.449659720456 -2.55246082325729 0.0111635195216595 CNIH1 other 0.0158587173367624 1 1 3.93506827570923 -2.55246082325729 0.219870532724486 9.72228812442339 5.63993223675569 1.72383066254995 0.0857133864030456 2.13442401476212 16.9075846576402 0.126240622654379 0.899621486213973 CGRRF1 other 1 1 1 1.72383066254995 0.126240622654379 3.66900943380301e-24 405.233156729952 41.7606821296407 9.70370061178498 1.15754472072091e-19 -450.087722404735 136.019133493296 -3.30900301189552 0.00104407599776349 ATP6V1D essential 5.45031351391437e-20 1 1.71501825822011e-15 9.70370061178498 -3.30900301189552 1.45364231991349e-16 766.432141604685 93.880818980161 8.1638842729594 7.81755304754645e-15 -533.382256949184 297.232842749608 -1.79449300425563 0.0736902135745695 PLEK2 other 2.03931481060664e-12 1 1.12455500588956e-10 8.1638842729594 -1.79449300425563 2.46916166508943e-15 66.8141845139286 8.17151614002468 8.17647341925544 7.10877260520254e-15 -19.5346487365816 25.877292578099 -0.754895384732579 0.450872221855031 PIGH other 3.4126283373201e-11 1 1.02281020243654e-10 8.17647341925544 -0.754895384732579 1.70475601537454e-06 256.316201186452 59.3414765014401 4.3193431693637 2.09425611319404e-05 -367.374010805777 184.029022919269 -1.99628300459401 0.0467554778018562 PSMA3 essential 0.0173271401402668 1 0.229823665861914 4.3193431693637 -1.99628300459401 6.08057108877992e-35 486.125695979022 37.4811091218326 12.9698855601863 3.76248537023402e-31 -312.554660125398 118.693962084543 -2.63328188423581 0.00887092667158306 VTI1B other 9.24915668314314e-31 1 5.72274024812594e-27 12.9698855601863 -2.63328188423581 9.61979642436498e-14 125.48896376958 15.9065997326769 7.88911306492412 4.94050886420451e-14 -7.75984590725614 49.3040930340483 -0.157387458722694 0.875039380903099 TIMM9 essential 1.29376642111285e-09 1 7.05801096340256e-10 7.88911306492412 -0.157387458722694 8.14520479008573e-08 148.964153586236 26.8836193985889 5.541075082846 6.28645161637508e-08 -54.7267671261611 87.6544208693862 -0.624346913519734 0.532844644572342 GSTZ1 other 0.000903058855076805 1 0.000788949677855073 5.541075082846 -0.624346913519734 4.24752180859537e-08 50.1341335545755 9.57782229604504 5.23439796698644 3.00778666688087e-07 -50.3673756085641 30.0888749294916 -1.67395343716214 0.095119906056849 KIAA0586 other 0.000477846203466979 1 0.00367190596292816 5.23439796698644 -1.67395343716214 4.27832369240306e-08 98.828258393179 16.5956982537525 5.9550527421064 6.84031184975934e-09 41.6351473345025 54.1105086256397 0.769446608283665 0.442195807310365 TMED8 other 0.000481183065684573 1 8.89035331113222e-05 5.9550527421064 0.769446608283665 0.0323512644715185 4.43022793767181 1.69655484151546 2.61130841707095 0.00944450077349537 1.39006422010863 5.53164103022516 0.251293280332771 0.801748662422162 SAMD15 other 1 1 1 2.61130841707095 0.251293280332771 2.06051920230339e-18 606.894707267712 64.8355348845313 9.36052595769527 1.44967982537336e-18 -23.2345721709621 211.39717750798 -0.109909566650127 0.912549990085319 AHSA1 other 2.94880903041638e-14 1 2.13769787049556e-14 9.36052595769527 -0.109909566650127 4.96949758573098e-17 593.520047257259 69.7906689227714 8.50428941889114 7.17447508339416e-16 -301.314559938951 220.704987479281 -1.36523675056159 0.173140650871359 DAAM1 other 7.00599769636353e-13 1 1.04051412134466e-11 8.50428941889114 -1.36523675056159 0.521266403177185 -4.37037778983863 4.49188848648186 -0.972948861707296 0.331313591478607 5.35899027862575 14.6458658729969 0.365904639923427 0.71467800535217 ISM2 other 1 1 1 -0.972948861707296 0.365904639923427 1.94356561467845e-05 267.656565161469 67.6673775626638 3.95547418567542 9.40987846867929e-05 -363.902962560667 218.392717529887 -1.66627791748994 0.0966365671116469 SPTLC2 other 0.180615552572068 1 0.977686372895778 3.95547418567542 -1.66627791748994 8.56871488288183e-05 101.601975715168 23.2642511741361 4.3673004970013 1.70107007690351e-05 57.5035351758292 69.5272393896391 0.827064840782365 0.408816608975938 RIN3 other 0.743336016089999 1 0.187883189993993 4.3673004970013 0.827064840782365 0.00043443295676265 235.530327976201 84.1832649889784 2.79782838081937 0.00545644864871513 -477.473684591704 251.589014135009 -1.89783201080266 0.0586180066263263 LGMN other 1 1 1 2.79782838081937 -1.89783201080266 6.03110609660105e-25 70.6074784719208 6.3508027999002 11.1178823680418 1.68765702202182e-24 -12.1478981321545 20.4968646920328 -0.592671040897119 0.553819904335769 ALKBH1 other 8.9887605263742e-21 1 2.54026134954724e-20 11.1178823680418 -0.592671040897119 1.79925138680896e-24 361.755375728816 33.0664911728497 10.9402407965755 7.05924526904852e-24 -80.966942504411 106.720270927141 -0.75868381705747 0.448600155107967 SNW1 essential 2.67530688704625e-20 1 1.06100456393799e-19 10.9402407965755 -0.75868381705747 0.341440751062386 6.17701921457837 9.20427482353694 0.671103300694874 0.502638843844947 39.7464076397217 27.5077763850633 1.44491532442819 0.149460164043192 CHGA other 1 1 1 0.671103300694874 1.44491532442819 8.6332976857212e-13 325.502319968568 46.8620214945223 6.94597265733865 2.106893964957e-11 -189.175834183808 140.051229774992 -1.35076167833542 0.177726157517499 ITPK1 other 1.13916362963091e-08 1 2.89740058060886e-07 6.94597265733865 -1.35076167833542 5.66148594872054e-15 349.172988294846 46.5519087415213 7.5007233373313 6.35135332582537e-13 -330.385751984588 151.20086006574 -2.1850785229723 0.0296102887497572 DHRS7 other 7.78114628792151e-11 1 8.93317845277339e-09 7.5007233373313 -2.1850785229723 3.02337752726168e-11 211.120767067991 29.9416224433084 7.05107972915387 1.10516483049756e-11 9.67210100933863 97.2505572291157 0.0994554816436868 0.920839103288236 PPM1A other 3.84361985040778e-07 1 1.52822192761202e-07 7.05107972915387 0.0994554816436868 0.0123815855293963 37.6155115536355 19.5036130499481 1.92864324457747 0.0546622481189269 168.69885808995 63.2481971317673 2.66725164890461 0.00803766685197964 SIX4 other 1 1 1 1.92864324457747 2.66725164890461 0.477573700513961 18.4870543131786 16.2321695659079 1.13891456333765 0.255598721486961 -7.93003987959817 51.9095208749339 -0.152766578191005 0.878679545959577 GALNT16 other 1 1 1 1.13891456333765 -0.152766578191005 0.215934513326342 49.260598085468 29.146526397329 1.69010184657827 0.0919823242333924 81.2705381841519 87.682403301019 0.926873980690803 0.354690491008225 ASB2 other 1 1 1 1.69010184657827 0.926873980690803 0.222098476504371 9.45485797624211 5.92722897893573 1.59515652421105 0.111676843667711 -5.41890191876007 17.9419511815447 -0.302024114541902 0.76283235981313 CEP128 other 1 1 1 1.59515652421105 -0.302024114541902 9.129881551385e-14 406.906449563442 58.3952662041525 6.96814101576108 1.8656860815951e-11 -458.428067700327 186.744617083615 -2.45483952822622 0.0146317242843655 ERH essential 1.22842556273885e-09 1 2.56811689131565e-07 6.96814101576108 -2.45483952822622 2.12181412837369e-11 1771.94045386208 300.764118917054 5.89146225368312 9.77304860288418e-09 -2785.13517189437 991.502576550419 -2.80900447236785 0.00527797005437326 HIF1A other 2.70722264639199e-07 1 0.000126277560997867 5.89146225368312 -2.80900447236785 6.45348073260287e-05 283.052550441229 74.9511288718631 3.77649482671752 0.000189897899048809 -342.81614773359 239.689289406227 -1.43025225942651 0.153629531255309 SUSD6 other 0.5677772348544 1 1 3.77649482671752 -1.43025225942651 0.00306258390458384 91.8039920085083 91.511938359831 1.00319142675712 0.316533649944817 -866.428797710311 292.64978136825 -2.96063367503445 0.00330171113401833 SRSF5 other 1 1 1 1.00319142675712 -2.96063367503445 6.59397964919816e-10 757.300990332473 134.244486410292 5.64120740138205 3.74364602595513e-08 -711.566341626671 395.353278368173 -1.79982405752059 0.0728391475871806 EIF5 essential 8.02685142696892e-06 1 0.000473908150425659 5.64120740138205 -1.79982405752059 0.34311717108419 4.38093078294138 3.34448453384129 1.30989715712923 0.191176098915244 9.60534847143387 10.1100485696865 0.950079359681224 0.342793426418932 SLC8A3 other 1 1 1 1.30989715712923 0.950079359681224 5.99609414896433e-07 272.391392687705 61.648367360685 4.41846888002775 1.36500646892023e-05 -345.506075526931 181.845902018478 -1.89999374025939 0.0583383364175483 DICER1 other 0.00630309416939131 1 0.151734119085172 4.41846888002775 -1.89999374025939 1.86970898906053e-22 175.532480547042 21.3255704714635 8.23108018526059 4.88659329059386e-15 -268.10595492542 62.8043238453494 -4.26890918506836 2.59822840534017e-05 ZFYVE21 other 2.75576407897631e-18 0.378224108965368 7.04304690973293e-11 8.23108018526059 -4.26890918506836 4.04413714248063e-11 511.183030728054 76.0956695043449 6.71763628676488 8.56446457463314e-11 -223.113672512147 254.50798475857 -0.876647043996659 0.381342217102353 MTHFD1 other 5.1259438280942e-07 1 1.16502411608735e-06 6.71763628676488 -0.876647043996659 0.0282945917290971 -12.7910179301695 5.56160815866371 -2.29987758311308 0.0221025089576102 11.5729645582399 16.4743146776466 0.702485340646237 0.482890433010033 TCL1A og 1 1 1 -2.29987758311308 0.702485340646237 2.621516799302e-15 222.265786092102 29.4968598814864 7.53523551269964 5.17816335285869e-13 -163.15881075077 86.5392171898 -1.88537423897567 0.0602965643680408 ZC3H14 other 3.62083900319592e-11 1 7.29033618448974e-09 7.53523551269964 -1.88537423897567 9.63453439932206e-07 102.755807595926 41.3297111861429 2.48624547926622 0.0134196644299779 -443.793368463653 115.716149826039 -3.83518954900267 0.00015111322696651 TELO2 essential 0.00998908526521712 1 1 2.48624547926622 -3.83518954900267 4.93606592103186e-09 249.986633860075 40.4658463447212 6.17771914939042 1.98075685557674e-09 -4.77900773327261 123.798261407029 -0.0386031894063519 0.969230906492382 PCNX1 other 5.81419204838342e-05 1 2.61598557916021e-05 6.17771914939042 -0.0386031894063519 0.041165917869981 21.9275084598868 10.5756835966611 2.07338922911892 0.0389409235742366 -26.3241938004867 31.3267555951806 -0.84031024918956 0.401365807224722 BDKRB1 other 1 1 1 2.07338922911892 -0.84031024918956 3.69775209735497e-10 79.4243226646581 18.1721050136398 4.37067266588229 1.67954533468186e-05 -206.668830694352 53.828491294121 -3.83939482095282 0.000148830634966776 GSKIP other 4.5460164284882e-06 1 0.185606554935693 4.37067266588229 -3.83939482095282 0.0209707831869611 36.6804182155862 18.9462958746335 1.93602055295126 0.0537539772313834 -79.9567644425546 56.4737335224842 -1.41582217883153 0.157809328965896 VRK1 essential 1 1 1 1.93602055295126 -1.41582217883153 2.6736360398051e-06 115.919460971669 24.0283463471498 4.82427959448066 2.18361132079571e-06 -26.5673808021223 70.5939805706417 -0.376340597135432 0.706914666769945 PSMC1 other 0.0267657703944888 1 0.0255373343967059 4.82427959448066 -0.376340597135432 0.941341638055599 -14.6731802885734 61.0029925149583 -0.240532139222112 0.810071775068533 35.4465090211927 188.159418485185 0.188385515360123 0.850693863869955 PAPLN other 1 1 1 -0.240532139222112 0.188385515360123 0.956390210941556 0.207295511843983 15.2337252099727 0.013607670414606 0.989151491266732 -12.5279707035918 44.6110075540215 -0.280826894313497 0.779025223671322 RPS6KA5 other 1 1 1 0.013607670414606 -0.280826894313497 3.1336757512612e-13 315.645071518929 45.0339614810751 7.00904519917873 1.44185625569988e-11 -207.796375401381 133.651439670144 -1.55476346468268 0.1209970478045 PPP4R3A other 4.17092242492866e-09 1 1.98889651911241e-07 7.00904519917873 -1.55476346468268 0.00928811512132297 11.7770106848465 5.71090573739285 2.0621966508281 0.0399959495574015 -27.8608974036117 15.7194846396195 -1.77237982302491 0.0772829297925874 C14orf93 other 1 1 1 2.0621966508281 -1.77237982302491 3.17378263466694e-15 690.671554057857 91.466646217056 7.55107552996806 4.54839108320241e-13 -594.678248479167 251.765412766718 -2.36203314007309 0.018773424679998 PSMB5 essential 4.37537674015184e-11 1 6.40777335801555e-09 7.55107552996806 -2.36203314007309 2.75851439377628e-08 375.804336672638 68.2342891669574 5.50755846159855 7.48295808993611e-08 -236.470657112396 189.271339099293 -1.24937382615728 0.212441448521019 ACIN1 essential 0.000313477575708737 1 0.000937090841602699 5.50755846159855 -1.24937382615728 5.19129051741545e-07 178.520285561643 32.4375052598094 5.50351465477317 7.6415030846211e-08 103.138775136796 96.1782251243062 1.07237137099893 0.28436131639033 CCNB1IP1 other 0.00548200278639071 1 0.000956257696009485 5.50351465477317 1.07237137099893 7.02309428607887e-12 170.553527293957 26.9440154066791 6.32992242320641 8.31118461759477e-10 -154.538320649166 79.4743743768558 -1.94450502895899 0.0527132810589729 TRIP11 other 9.07032627047086e-08 1 1.10846269244861e-05 6.32992242320641 -1.94450502895899 2.65515432267479e-17 715.65894402389 85.3619552875985 8.38381620492077 1.66640365807489e-15 -543.709398289637 241.384875344237 -2.2524584339191 0.0249727899309961 APEX1 other 3.75624682028802e-13 1 2.41045289140533e-11 8.38381620492077 -2.2524584339191 4.78595027115623e-06 312.751810502907 82.295494734632 3.80035154429046 0.00017295152773262 -521.024445438115 225.716055724969 -2.30831804926174 0.0216186540758193 PABPN1 essential 0.0469913664358805 1 1 3.80035154429046 -2.30831804926174 0.000125281479000522 209.655973589468 55.2432755339882 3.79514016073283 0.000176464118511106 -157.845132384787 151.482095242991 -1.04200520947105 0.29819584924592 EFS other 1 1 1 3.79514016073283 -1.04200520947105 1.89613809314708e-16 571.333508028177 66.922207262468 8.53727830266289 5.99024640362639e-16 -202.988775423721 211.426307614008 -0.960092325853362 0.337747451404244 ARHGAP5 other 2.65724792373631e-12 1 8.69064948238117e-12 8.53727830266289 -0.960092325853362 5.50663433535799e-11 126.361754806178 22.3607626741515 5.65104851956812 3.55403685550788e-08 -160.481774976363 66.1560775729819 -2.42580547190578 0.0158322856609771 CINP essential 6.95047385808885e-07 1 0.000450225388855738 5.65104851956812 -2.42580547190578 0.099552586817441 391.79964471756 399.783309643628 0.980030019429313 0.327811640767537 2273.82442785064 1082.21152581345 2.10109056650594 0.0364148670763353 DHRS2 other 1 1 1 0.980030019429313 2.10109056650594 1.04434049538445e-28 362.126242857732 30.1618052208174 12.0061196671277 1.57683685538861e-27 -106.61621843824 97.2045262063594 -1.0968236007025 0.273569790160669 SRP54 essential 1.57361225844529e-24 1 2.38654258063065e-23 12.0061196671277 -1.0968236007025 4.75458442826572e-18 519.485034530154 60.3336038449152 8.6102105862177 3.43536390779025e-16 -315.19690255006 167.368443946572 -1.88325167586955 0.0605787369685607 CHD8 other 6.78003739470691e-14 1 4.99158375801923e-12 8.6102105862177 -1.88325167586955 0.0611872195520838 62.5924763739519 43.2513586710028 1.44717942504581 0.148828640870311 -173.364700074515 117.495931193531 -1.4754953496131 0.141065741625417 PCK2 other 1 1 1 1.44717942504581 -1.4754953496131 3.65145012648105e-29 592.80555359711 49.3734034543975 12.00657666115 1.5709022255513e-27 -234.015177189195 159.119066476422 -1.4706922455699 0.142388637944868 KIAA0391 other 5.50821251579666e-25 1 2.37771760859445e-23 12.00657666115 -1.4706922455699 1.10242212817594e-07 168.00526305998 47.9268157256556 3.5054543164662 0.000521096500490756 -474.020481168428 130.197201102078 -3.64078856654363 0.000317017625670382 DCAF11 other 0.00121354627869607 1 1 3.5054543164662 -3.64078856654363 3.69152371897104e-22 871.510832301778 86.0267129313898 10.1307001349319 5.0454981549819e-21 -372.582763794725 278.422478360552 -1.33819211002151 0.181814531864535 PSMA6 essential 5.43170800009398e-18 1 7.52384684870901e-17 10.1307001349319 -1.33819211002151 1.22269934258688e-05 885.116185724361 197.216115820918 4.48805201359959 1.01447794777849e-05 -497.069677979519 638.283131697644 -0.778760479941655 0.43671485754054 NFKBIA other 0.115826308723256 1 0.113793991402314 4.48805201359959 -0.778760479941655 0.00055575501946123 58.6695175392699 15.4188404627143 3.80505380292015 0.000169932358461164 0.712581611896656 41.8865689716633 0.017012174293357 0.986437538585291 EMC9 other 1 1 1 3.80505380292015 0.017012174293357 1.48729988368716e-14 67.2204716437238 8.61174521626615 7.8056735255887 9.170678610599e-14 -34.4619703691628 27.7456055313717 -1.24206949926528 0.215149754864808 BRMS1L other 2.02897450132603e-10 1 1.30572122057709e-09 7.8056735255887 -1.24206949926528 0.205897920360714 -14.3426331493825 27.8527466281614 -0.514945019277953 0.606946945207235 -135.007836807053 75.835402805899 -1.78027453948661 0.0759797868607885 REC8 other 1 1 1 -0.514945019277953 -1.78027453948661 5.30811553327844e-24 374.48807778603 36.783168987408 10.1809628722916 2.83913692694244e-21 -224.224095822396 100.150497682593 -2.23887150848744 0.0258513078878106 TM9SF1 other 7.87777426293853e-20 1 4.23712794976889e-17 10.1809628722916 -2.23887150848744 6.64468247855634e-20 515.108237399522 51.9485532035828 9.91573789131044 2.60889468587767e-20 76.737431010779 149.337230295052 0.513853316143373 0.607720617947199 SEC23A other 9.63412512565884e-16 1 3.88073084524303e-16 9.91573789131044 0.513853316143373 9.26634836332739e-19 207.239449264321 25.0850398823163 8.26147577347144 3.85676050464248e-15 -203.995294259481 68.2996951530116 -2.98676727330146 0.00303718814633581 GMPR2 other 1.33055496149018e-14 1 5.5641483800477e-11 8.26147577347144 -2.98676727330146 0.0361420131443003 156.684051921996 61.7628637302103 2.53686507488409 0.0116751573687322 19.3290778041245 177.550565622378 0.108865199817129 0.913379841627078 PNN essential 1 1 1 2.53686507488409 0.108865199817129 1.62058328379168e-10 111.133395193761 33.1494527422623 3.35249562210954 0.000896898805748211 -460.057037093035 90.2568832821252 -5.09719614021002 5.90889380372482e-07 RABGGTA essential 2.01454708008144e-06 0.00887752205071616 1 3.35249562210954 -5.09719614021002 0.0460085297688006 43.2297986423316 22.9636565278403 1.88253114611436 0.060671034514824 127.821919540929 62.5237491272879 2.04437387912719 0.0417347181997217 NFATC4 other 1 1 1 1.88253114611436 2.04437387912719 0.000141925358133837 689.256062133604 172.013628915381 4.00698518181179 7.65455507684346e-05 -366.17745715246 782.013155185405 -0.468249740716502 0.639924782469142 PLTP other 1 1 0.803039373111648 4.00698518181179 -0.468249740716502 4.11545108675684e-12 168.760663156716 23.3143227342087 7.2384973426269 3.39018202357151e-12 -36.3253984541279 105.992223972894 -0.342717579578456 0.732035947735886 PCIF1 other 5.34679405191449e-08 1 4.72354061344218e-08 7.2384973426269 -0.342717579578456 0.000135989598034032 113.912705651456 29.7808116956278 3.82503696728253 0.000157914365315206 -396.290151659577 265.148303346895 -1.4945981047486 0.13603004627289 GSS other 1 1 1 3.82503696728253 -1.4945981047486 0.0290077026194145 1504.78498935813 600.053641544506 2.50775078288817 0.0126450119988741 -831.961048504526 2727.98059353512 -0.304973228356588 0.760584802665306 MMP9 other 1 1 1 2.50775078288817 -0.304973228356588 5.72559258040717e-11 182.330082677881 28.4157083861011 6.41652427595519 5.17120562713308e-10 -608.756907877111 252.99434226237 -2.40620759513189 0.0167003200576849 TRPC4AP other 7.22168992166757e-07 1 6.92786417867019e-06 6.41652427595519 -2.40620759513189 1.71616377533613e-06 1272.77274230625 306.808193374583 4.14843139717692 4.320979074555e-05 -2699.25085950573 1361.13376108009 -1.98309008026061 0.0482339311154258 PYGB other 0.0174362239574151 1 0.463641054699751 4.14843139717692 -1.98309008026061 7.40286596829e-10 258.83964668695 46.1402870048812 5.60984041255677 4.46823246218325e-08 -410.590387225969 204.698256906041 -2.00583235749992 0.0457371649810462 ABHD12 other 8.995962724666e-06 1 0.000563935619052149 5.60984041255677 -2.00583235749992 0.00285186600017162 76.7462483483737 25.0702193378645 3.06125157159918 0.00239515121809184 -266.356080548099 217.153761431098 -1.22657824940607 0.220903042711748 PROCR other 1 1 1 3.06125157159918 -1.22657824940607 3.25517485735263e-07 156.73161390758 28.9826019538338 5.40778271589407 1.27410780870252e-07 10.2424084509647 128.591125671887 0.0796509743378347 0.9365660798708 GINS1 essential 0.00349084951702496 1 0.00157938403966765 5.40778271589407 0.0796509743378347 9.64408351608453e-06 80.1406097478374 17.9899879482371 4.45473393191966 1.17435841994311e-05 -58.5816808704763 79.7736462741538 -0.734348793198593 0.463291270944542 NINL other 0.0921685061632198 1 0.131070143249851 4.45473393191966 -0.734348793198593 0.264303556110014 49.019876778313 38.6322319792593 1.26888544272126 0.205404115899331 -122.354456368321 175.630930016695 -0.696656655844674 0.486523430071033 CD40 other 1 1 1 1.26888544272126 -0.696656655844674 3.65422856388718e-07 57.6607627253869 11.7812884228456 4.89426628530494 1.58037452836984e-06 -211.342747726185 102.078552655746 -2.07039326310715 0.0392326094700192 UQCC1 other 0.00390563948908262 1 0.0186420979366507 4.89426628530494 -2.07039326310715 0.00218379651499499 122.358748019761 34.7371044654032 3.52242220250758 0.000489822711484863 89.6400760312391 160.701426290647 0.557805105407807 0.57736748703725 ZMYND8 essential 1 1 1 3.52242220250758 0.557805105407807 5.58291526126719e-07 74.7744335592552 15.2962264360871 4.88842355150066 1.61322204452194e-06 -86.8934768366872 69.2983443989921 -1.25390408083041 0.210794975029979 IFT52 other 0.00588160122774498 1 0.0190198879049137 4.88842355150066 -1.25390408083041 0.000287915322605059 366.317861748767 101.871072572601 3.5958967791146 0.000374463131325363 -447.666831977145 454.563438305169 -0.984828066344847 0.325454887319223 MYBL2 essential 1 1 1 3.5958967791146 -0.984828066344847 1.59319129187428e-12 191.322186648933 26.268062752259 7.2834524743352 2.62482880558854e-12 -134.018931616757 140.504022177288 -0.953844093143837 0.340893942211887 NDRG3 other 2.0897890175515e-08 1 3.66452349548215e-08 7.2834524743352 -0.953844093143837 0.00416712766147662 49.5286403556252 16.2771449107093 3.0428334101172 0.00254086263557549 -68.2473891994183 88.946726038765 -0.76728388147389 0.443487465740276 SLA2 other 1 1 1 3.0428334101172 -0.76728388147389 1.35141876607096e-08 509.381311518765 86.1697887222787 5.91136776672945 8.81575792569669e-09 -325.772383135756 470.876227516783 -0.691842917731803 0.489545599546801 C20orf24 other 0.000155845612103303 1 0.000114049460284738 5.91136776672945 -0.691842917731803 0.401892185277202 -10.9513008199855 16.0497397303949 -0.682335103493669 0.495520692377961 71.9365760339544 74.0932769509709 0.970892083522725 0.332335299143202 NFATC2 other 1 1 1 -0.682335103493669 0.970892083522725 0.0875505789026381 10.4758354346801 4.86422172690118 2.15365088658364 0.0320165075994961 22.6479790065402 21.7048598490323 1.04345198098803 0.297529104071658 RIMS4 other 1 1 1 2.15365088658364 1.04345198098803 0.0669163792251414 27.9871444379352 14.6804311202461 1.90642524110464 0.0574934407831646 -54.2506590509663 65.6025329372917 -0.826959823377911 0.408877973934948 PABPC1L other 1 1 1 1.90642524110464 -0.826959823377911 5.58801349420141e-10 148.901609618656 26.3640584363853 5.64790166802072 3.59664748336401e-08 -254.740396685914 117.813230263271 -2.16223930127931 0.0313427794207661 STK4 other 6.82570558090685e-06 1 0.000455551370242885 5.64790166802072 -2.16223930127931 0.00123195695746476 12.7771740984213 3.53209094346149 3.61745331673128 0.000345597655682899 1.81275846174213 16.282027964774 0.111334931107109 0.911420555420746 SALL4 other 1 1 1 3.61745331673128 0.111334931107109 0.000136493469143083 282.271851950099 67.5926708920314 4.17607187620954 3.82853650159759e-05 29.3314445320001 312.040105845124 0.0939989571294349 0.925168813092161 ADNP other 1 1 0.412639664142189 4.17607187620954 0.0939989571294349 9.06707521858197e-06 67.486905263638 14.8332030017684 4.54971898217751 7.63636105600845e-06 -47.5929987672972 67.9860023335235 -0.700041142790203 0.484410220153536 PFDN4 other 0.086889781819671 1 0.0864283344319037 4.54971898217751 -0.700041142790203 0.918471627533407 1.67323495986988 4.09407293117489 0.408696910875425 0.683035469652795 2.84619016301253 18.7646357849541 0.151678412287366 0.879536163837315 DOK5 other 1 1 1 0.408696910875425 0.151678412287366 1.03567820178826e-13 116.359724636434 14.8887113193412 7.81529859372561 8.02869788567834e-14 -25.4825963342226 70.7964948101023 -0.359941497140143 0.719129064780989 CSTF1 essential 1.39164079974289e-09 1 1.14400916173031e-09 7.81529859372561 -0.359941497140143 0.498014951662426 96.7186014576951 111.802017257187 0.865088160575903 0.387640489188653 517.377448436447 524.16739835734 0.987046218551226 0.324368039977288 BMP7 other 1 1 1 0.865088160575903 0.987046218551226 3.7782955614675e-09 145.255239584387 25.0338317690566 5.80235742272309 1.57632286172218e-08 -165.312734916804 119.469753278656 -1.38372040102252 0.167411529100321 RAE1 essential 4.47123496744064e-05 1 0.000202541724502683 5.80235742272309 -1.38372040102252 1.28277605609602e-18 732.093132001947 94.7549170217991 7.72617564356605 1.47186088571002e-13 -1676.79938389437 427.46137631004 -3.92269214675942 0.000107390178115251 TPD52L2 other 1.83975741965292e-14 1 2.08871778291109e-09 7.72617564356605 -3.92269214675942 1.50012695932109e-10 543.784802727714 97.2991878215707 5.58879076899303 4.93193903511613e-08 -1214.70501968115 438.939171151289 -2.76736527408824 0.00598317131121741 DNAJC5 other 1.86585791200358e-06 1 0.000621621595986037 5.58879076899303 -2.76736527408824 3.20359419034987e-17 402.589171568433 44.5962469677894 9.02742268557287 1.68051280235336e-17 8.50711717157352 209.371895737311 0.0406316098042452 0.967614922512235 NELFCD essential 4.52667859096437e-13 1 2.46127905032673e-13 9.02742268557287 0.0406316098042452 0.0611455162306756 351.550759185518 162.862865850617 2.15856915785806 0.0316268415763416 -362.717373452046 764.613824858037 -0.474379826338336 0.635552620357607 CTSZ other 1 1 1 2.15856915785806 -0.474379826338336 1.63188620812439e-15 527.482237637622 66.8107980167666 7.89516445388435 4.81924883080367e-14 -574.095488156649 306.296142611281 -1.87431510975713 0.06180945885036 PRPF6 essential 2.26130471859797e-11 1 6.88574272945228e-10 7.89516445388435 -1.87431510975713 9.00286616600512e-10 283.877972572179 46.2211197782438 6.14173723904023 2.41897043653316e-09 -247.852290340237 217.000400909563 -1.14217434300286 0.254235456509702 PRELID3B other 1.09069723601152e-05 1 3.1872354471761e-05 6.14173723904023 -1.14217434300286 2.3448520941074e-16 113.051697409556 14.738327954112 7.67059179043538 2.07877728288529e-13 -192.027847254579 67.1714380374166 -2.85877231253577 0.00453184536624224 MTG2 essential 3.28326190216918e-12 1 2.94354863256558e-09 7.67059179043538 -2.85877231253577 4.47858999675665e-07 593.283007203552 140.31724673399 4.22815456412342 3.07848368899327e-05 -1624.38113278939 638.552749050557 -2.54384799878261 0.0114338188450462 PSMA7 essential 0.00475133612755913 1 0.333945037657311 4.22815456412342 -2.54384799878261 0.319539193495969 0.863344788087094 32.8815605473276 0.0262561987240372 0.979069408439488 -224.450724637681 152.301220199544 -1.47372899799231 0.141540662489242 SLCO4A1 other 1 1 1 0.0262561987240372 -1.47372899799231 0.184560526473282 14.4894317448793 10.7302869181541 1.3503303178562 0.177864278737031 -45.173940053987 48.904380815152 -0.923719701609857 0.356328261509392 NTSR1 other 1 1 1 1.3503303178562 -0.923719701609857 1.7328517041452e-12 151.624053487767 21.0239350623922 7.21197306963687 4.00953943173715e-12 -93.9208812485053 95.8187357306123 -0.980193284041623 0.327731184722004 MRGBP essential 2.27038230277104e-08 1 5.58087793503494e-08 7.21197306963687 -0.980193284041623 1.30600980997257e-08 67.917812200158 11.1151790237999 6.11036601882273 2.88548582567848e-09 16.6257752419937 50.658565978216 0.328192772948667 0.742980552070801 TCFL5 other 0.000150687411874635 1 3.79239402068923e-05 6.11036601882273 0.328192772948667 2.17011867507325e-09 243.824602124228 38.8481813423982 6.27634534484943 1.12645517374071e-09 -57.3036318818954 177.054562365006 -0.323649563820679 0.746414775445679 DIDO1 essential 2.59068767430245e-05 1 1.49728421693615e-05 6.27634534484943 -0.323649563820679 9.46584981751055e-19 448.840466655424 51.2527871929261 8.75738650009208 1.18004422431777e-16 -514.308491287847 233.589823071756 -2.20175898300953 0.0283956012347369 GID8 other 1.35882274130364e-14 1 1.72026847021045e-12 8.75738650009208 -2.20175898300953 0.00356748557133318 35.1419499176283 10.5050383385718 3.3452471837819 0.000919848880418447 60.3288922174232 47.8777873607563 1.26006015613981 0.208565795043825 SLC17A9 other 1 1 1 3.3452471837819 1.26006015613981 2.4231155141091e-08 322.592154522274 61.4198680183897 5.25224434584728 2.74653819410936e-07 -512.396921852676 280.152600949106 -1.82899219966821 0.0683313074221149 ARFGAP1 other 0.000276259399763579 1 0.00336011482667339 5.25224434584728 -1.82899219966821 0.313514699166584 301.715238039727 203.821322381916 1.48029280996607 0.139778971396638 -15.96520762903 932.326815991868 -0.0171240463699901 0.98634832710012 EEF1A2 other 1 1 1 1.48029280996607 -0.0171240463699901 1.22219799310023e-05 133.926996588934 51.138291049482 2.61891811087986 0.009240797635525 -784.792519222094 233.918608280304 -3.35498114062682 0.000889152694567055 PTK6 other 0.115791037866315 1 1 2.61891811087986 -3.35498114062682 6.76080765545199e-11 107.915265611755 15.8865751704535 6.79285903058951 5.41690816784738e-11 -32.2455724833338 71.7733154927981 -0.449269652125369 0.653543185293647 GMEB2 other 8.50915251515187e-07 1 7.39137119502775e-07 6.79285903058951 -0.449269652125369 1.9844271894419e-13 356.353860238548 47.7080300213406 7.46947337962068 7.72664029061842e-13 -124.71371732753 176.372963275538 -0.707102239546185 0.480017544370024 C20orf27 other 2.65298070956488e-09 1 1.08582476004061e-08 7.46947337962068 -0.707102239546185 1.8119081741068e-07 944.607040757273 178.646420891886 5.28757887250893 2.30076964535135e-07 -396.957110859685 660.442248761406 -0.601047421790684 0.548233902738155 CDC25B other 0.00197026894852374 1 0.00282373458573972 5.28757887250893 -0.601047421790684 0.409949707786443 8.26785535284685 9.13743025946713 0.904833757202215 0.366247179390082 -25.2660624134287 35.6737656825224 -0.708253304074574 0.479313392420622 ISM1 other 1 1 1 0.904833757202215 -0.708253304074574 4.81330243575684e-06 140.643391804784 29.8745656435549 4.70779704323922 3.73500014753671e-06 -47.8461129872262 110.444000030318 -0.433216045906449 0.665149686704241 RNF24 other 0.0472473767093892 1 0.0430981667024261 4.70779704323922 -0.433216045906449 1.46591067727847e-05 125.087242158801 41.1021128189061 3.04332876292587 0.00253490521710996 -540.244650874385 185.693573291902 -2.90933413201728 0.00387721404133457 ARFRP1 other 0.137927535625131 1 1 3.04332876292587 -2.90933413201728 9.48247038839009e-09 43.152726855421 7.2266577157811 5.97132568783311 6.38236191449815e-09 -8.5234714955774 28.5489813286128 -0.298556063961374 0.765476900873521 NDUFAF5 other 0.000110214753324258 1 8.3021763783792e-05 5.97132568783311 -0.298556063961374 0.0666558021543328 80.8764975492795 62.832235899045 1.28718159384344 0.198964161686385 -363.415973875972 236.714318282291 -1.5352513380394 0.125713299895629 TRIB3 other 1 1 1 1.28718159384344 -1.5352513380394 0.131758503296612 -60.1073200350511 36.062083512554 -1.6667733580653 0.0965378861886078 -211.947560267595 135.129739366574 -1.56847457311105 0.117758693787932 RASSF2 other 1 1 1 -1.6667733580653 -1.56847457311105 2.37767122733939e-24 452.425699535953 45.7280935051742 9.89382379312971 2.64003030995419e-20 -479.304482657382 172.27613064444 -2.78218741542678 0.00572085738725184 CSNK2A1 other 3.53369497807181e-20 1 3.92678108302587e-16 9.89382379312971 -2.78218741542678 0.00295976665385777 58.8447686699234 18.0877868492215 3.2532873789618 0.00126300355833809 -14.8595224357145 68.1439721503516 -0.21806070246285 0.827521240107322 SLC52A3 other 1 1 1 3.2532873789618 -0.21806070246285 0.0286204038855952 14.518671962289 6.05699949879091 2.39700729134735 0.0171046108093136 -11.7597702602413 22.8191546373771 -0.515346446751323 0.60666788710657 RSPO4 other 1 1 1 2.39700729134735 -0.515346446751323 1.72108732655163e-11 238.41301802655 36.9087659089478 6.4595228844742 3.90454255726415e-10 -213.497469051841 139.594699716136 -1.52940956559228 0.127150827837922 CDS2 other 2.20075436446157e-07 1 5.24536247142866e-06 6.4595228844742 -1.52940956559228 1.86427717459223e-13 770.82599318553 99.7036879090099 7.73116831835739 1.53512255594536e-13 -750.64777647464 616.547663674419 -1.21750161536746 0.224348412270748 HM13 other 2.49328429329965e-09 1 2.17833890688647e-09 7.73116831835739 -1.21750161536746 0.00947030532141029 16.5833359657574 6.62819586659258 2.50193812909795 0.0128503698839155 -26.3562143635587 24.6516671929174 -1.06914531002313 0.285810012492436 SNPH other 1 1 1 2.50193812909795 -1.06914531002313 0.716304330790236 4.94332859712304 12.3241738634101 0.40110831378317 0.688618507142128 -50.1140897247133 76.2712297407413 -0.657051025597194 0.51163877096583 MYLK2 other 1 1 1 0.40110831378317 -0.657051025597194 0.00278532795493859 15.3727780620075 6.88097073661355 2.23410019464393 0.0261669039736765 -49.0954220812443 25.3510855271016 -1.9366201115435 0.0536719346563371 SIRPB1 other 1 1 1 2.23410019464393 -1.9366201115435 3.56860586341356e-13 306.581410607732 41.2846580749193 7.42603729577653 1.04228098317019e-12 -162.673441299297 172.195466424473 -0.944702231000069 0.345530396475123 SEC23B other 4.74339091364931e-09 1 1.463049816076e-08 7.42603729577653 -0.944702231000069 6.66560561991972e-09 901.364310645727 167.379222947963 5.38516247578683 1.40405441163589e-07 -1017.36183827807 626.462069786284 -1.62397994602473 0.105364670326446 FERMT1 other 7.79942513586806e-05 1 0.00173779814528174 5.38516247578683 -1.62397994602473 0.253102180644629 -1.47064326506863 1.40653405736681 -1.04557956301594 0.296572414912342 10.0255909423228 8.7040553243195 1.1518298734052 0.250281387523509 CCM2L other 1 1 1 -1.04557956301594 1.1518298734052 0.0295446548632541 46.4163640514115 17.5767152535332 2.64078716539947 0.00867971367364655 23.8334617549117 67.6047426093288 0.352541269073968 0.724665914687284 PLCB4 other 1 1 1 2.64078716539947 0.352541269073968 0.0214501438259685 467.289850251521 168.895359527548 2.76674179538546 0.00599648865125847 171.366722073237 922.931469586638 0.185676540155239 0.852817930848533 MYL9 other 1 1 1 2.76674179538546 0.185676540155239 0.702858681075129 25.7116083575687 30.8669869369559 0.832980828678975 0.405498907812488 40.5749945096055 191.014188804847 0.212418746290412 0.831920417814432 HCK other 1 1 1 0.832980828678975 0.212418746290412 5.07386807040198e-20 599.324746134618 59.8714366519478 10.0101948382947 1.29362011920759e-20 -150.257133472202 370.502437701826 -0.405549648753259 0.685354189807 TM9SF4 other 7.36471950418848e-16 1 1.92555354744049e-16 10.0101948382947 -0.405549648753259 0.465682933879821 5.48432948761553 6.76733745595863 0.810411705239641 0.418313483848978 -27.1494255785874 36.2360668419833 -0.749237650349291 0.454271349003883 TLDC2 other 1 1 1 0.810411705239641 -0.749237650349291 8.01791533371574e-23 182.35326105946 17.8044287103117 10.2420169737795 1.86907121037682e-21 -83.6309246630098 75.9427371883725 -1.10123663906882 0.271629142704995 CRNKL1 essential 1.18424609478982e-18 1 2.79164475981882e-17 10.2420169737795 -1.10123663906882 0.336134653480556 55.346207553663 119.225109742312 0.464216033629878 0.642812618349286 -816.80699685982 638.106671186323 -1.28004773142595 0.201467239362504 SAMHD1 other 1 1 1 0.464216033629878 -1.28004773142595 0.393926615792946 1.56456765660151 4.55657627196754 0.343364746515245 0.73155097070821 23.9658308162426 17.5362771495174 1.36664302302626 0.172702682154974 PAK5 other 1 1 1 0.343364746515245 1.36664302302626 2.10660986198407e-13 276.678799091494 34.62688326097 7.99028884598904 2.69653261325164e-14 348.140480416642 214.281556876397 1.6246870962276 0.105248785245879 KIF3B other 2.81485209758311e-09 1 3.8598167826084e-10 7.99028884598904 1.6246870962276 5.40806257808499e-09 28.279262776352 4.49509579871863 6.29113683948923 1.0457801897922e-09 9.20549337027309 23.5319353755395 0.391191511593297 0.6959184827383 MROH8 other 6.35825917305452e-05 1 1.39109680846158e-05 6.29113683948923 0.391191511593297 1.91370065028036e-17 252.289269379248 29.9832530953004 8.41433945067127 1.37345741685212e-15 -348.300783789909 156.886416240796 -2.22008247836653 0.0271201785351371 MANBAL other 2.71305341190247e-13 1 1.98835430237681e-11 8.41433945067127 -2.22008247836653 3.20229952839625e-11 308.086315082286 52.2143744764585 5.9004118726193 9.23063564467237e-09 -446.714974118668 191.066697120553 -2.33800542350305 0.0200027280478407 IDH3B other 4.06724063101607e-07 1 0.000119379810792548 5.9004118726193 -2.33800542350305 5.74331188451275e-24 727.990910624447 64.9611401773429 11.2065599316306 9.10765380449848e-25 17.5419748553735 434.557567948676 0.0403674360986973 0.967825683355168 MAPRE1 other 8.52135184305157e-20 1 1.37179481603356e-20 11.2065599316306 0.0403674360986973 4.31930124377052e-09 2068.97456296183 346.897226266855 5.96422919037768 6.55930453973734e-09 -840.898289661698 1350.4630798275 -0.622674031021353 0.533946414732885 JAG1 other 5.09936704839547e-05 1 8.52971962347444e-05 5.96422919037768 -0.622674031021353 1.93472970973027e-24 164.481513469731 14.7344031460919 11.1630930577163 1.39636790749068e-24 -106.965688239451 97.0735345566589 -1.10190371379769 0.271350117476401 CDK5RAP1 other 2.87636265945599e-20 1 2.10237152151797e-20 11.1630930577163 -1.10190371379769 0.000555139858500231 101.2093633206 27.1137557467211 3.73276812943332 0.000224905947929396 -131.938402072488 178.775960626709 -0.738009750360007 0.46106147290729 SNTA1 other 1 1 1 3.73276812943332 -0.738009750360007 2.6747549234198e-18 177.492375728712 19.0601849546894 9.31220636896514 2.19225415312797e-18 -37.6577159961663 99.7411095864055 -0.377554612659923 0.706014941382011 TTI1 essential 3.825434491475e-14 1 3.2291903675575e-14 9.31220636896514 -0.377554612659923 0.00688518760590089 115.230078280695 38.4451261229368 2.99726102893306 0.00294292319189063 -169.126635706656 241.633306255408 -0.699930975276596 0.484491958792902 E2F1 other 1 1 1 2.99726102893306 -0.699930975276596 5.43752776273014e-16 189.549814297897 22.4977898661743 8.42526378926169 1.2853127471703e-15 -116.022867377166 117.729944899718 -0.985500056727232 0.325132460346253 RPRD1B essential 7.58154495957464e-12 1 1.86113285790259e-11 8.42526378926169 -0.985500056727232 5.36401662449816e-18 132.945359756389 14.2342896648748 9.33979586522335 1.8922336693922e-18 -63.180469684167 89.4646167350939 -0.706206229790771 0.480586903650816 PXMP4 other 7.64640569822213e-14 1 2.78801708848246e-14 9.33979586522335 -0.706206229790771 7.29285281559836e-21 732.010087723706 74.4879865587147 9.82722344289308 5.01885700087463e-20 -1026.02863429077 468.200527361782 -2.19142989879195 0.0291621078942518 CHMP4B essential 1.0646835825492e-16 1 7.45601396049935e-16 9.82722344289308 -2.19142989879195 0.00679868622979354 360.664929272484 262.369540073991 1.37464482032012 0.170215577618765 -2682.64750997416 1127.41034078368 -2.37947747411064 0.0179304850161318 CST3 other 1 1 1 1.37464482032012 -2.37947747411064 0.590323497607093 246.877113328696 251.13552220448 0.983043382957523 0.326338136900203 -16.4903660117772 1079.13740517132 -0.015281062386267 0.987817594025405 CST4 other 1 1 1 0.983043382957523 -0.015281062386267 1.92344253245292e-19 75.543343954612 8.02522510772501 9.41323675542691 1.03688225876686e-18 -48.6172658021317 40.7084671096962 -1.1942789609622 0.233264551172552 ACTR5 other 2.7778357053685e-15 1 1.52991977281051e-14 9.41323675542691 -1.1942789609622 0.308746276536246 -228.315224972929 615.455113716482 -0.370969742365494 0.7109055344875 3800.17193950935 2797.99919568688 1.35817477909476 0.17536501143368 WFDC2 other 1 1 1 -0.370969742365494 1.35817477909476 4.18868374944547e-10 1345.00166410662 197.898392613141 6.79642540976001 5.47807493505835e-11 541.781235401056 1238.84423883596 0.437327969422632 0.662177040076985 AHCY essential 5.1386772238197e-06 1 7.47428544139361e-07 6.79642540976001 0.437327969422632 0.0103726206260028 -56.2822611404233 18.7645589619602 -2.99939163262615 0.00292018634967841 -11.0521687538406 95.1844242469423 -0.116113206979824 0.90763657654464 PPP1R16B other 1 1 1 -2.99939163262615 -0.116113206979824 1.7321943823326e-05 273.7128222141 58.2860188132562 4.69602878678426 3.96084533674191e-06 57.1426721123901 295.659554462915 0.193271860319865 0.846870228307283 FAM83D other 0.161856243085158 1 0.0456368599699402 4.69602878678426 0.193271860319865 0.000109187537466401 66.0056298073868 15.2657265666152 4.32377912177042 2.0585320219389e-05 92.4284798593014 77.4363733728132 1.19360548323085 0.233527635806659 DHX35 other 0.936610696386786 1 0.22608857196955 4.32377912177042 1.19360548323085 1.622690759705e-08 98.4787065456855 18.6346278940962 5.28471548266791 2.33410729891681e-07 -153.256281393525 84.7172648298514 -1.8090324528457 0.0713843277438918 DNTTIP1 other 0.00018652830282809 1 0.00286394965577092 5.28471548266791 -1.8090324528457 0.894794834450778 -2.07640953292687 17.8463191004231 -0.116349456783928 0.907450444648458 -51.3598318805528 109.622184283272 -0.468516771640265 0.639742239696443 MAP1LC3A other 1 1 1 -0.116349456783928 -0.468516771640265 0.18445521341133 14.0103532853711 7.72631959068898 1.81332821156596 0.0707358424138625 6.04984016091101 33.6852738761022 0.179598960161729 0.857583261389591 SYNDIG1 other 1 1 1 1.81332821156596 0.179598960161729 2.40771870254885e-20 199.77956074592 20.1857589380292 9.89705471858891 2.95450093159816e-20 -157.645900050405 123.867710995787 -1.27269567495089 0.204076675425813 PIGU other 3.50226762472756e-16 1 4.39363833537962e-16 9.89705471858891 -1.27269567495089 0.582776365328969 270.246922818417 296.606730066082 0.911128762176797 0.362913360283799 -362.26781494343 1348.44178505359 -0.2686566220054 0.788367053042089 TNNC2 other 1 1 1 0.911128762176797 -0.2686566220054 2.91165745750521e-10 85.8515664090214 15.1414215483964 5.66998059822946 3.19234480971887e-08 -164.643562226952 68.8363527571332 -2.39181123973612 0.017342407320059 ACOT8 other 3.59327646830718e-06 1 0.00040504470945713 5.66998059822946 -2.39181123973612 2.30811420477866e-13 611.436239020915 83.3115636617634 7.33915211942588 1.85293221347609e-12 -373.746558257723 363.222463949691 -1.02897423852477 0.30428373690407 APMAP other 3.08156327479999e-09 1 2.59206687343171e-08 7.33915211942588 -1.02897423852477 3.52364912920943e-14 152.517483604083 33.0960150595886 4.60833376252335 5.90397440414967e-06 -118.67522266785 50.0849709620324 -2.36947771733388 0.018415728399137 ZNF516 other 4.77172565077541e-10 1 0.067299404232902 4.60833376252335 -2.36947771733388 3.08486021479214e-14 196.442813535759 44.7718589496019 4.38764032015932 1.57268119695724e-05 -174.934843798796 66.1513493714547 -2.64446372539579 0.00859861769397519 ADNP2 other 4.18276196523666e-10 1 0.174095808503166 4.38764032015932 -2.64446372539579 1.15828990326897e-17 104.250983750239 28.0729090891308 3.71357964431988 0.000242270660271321 -178.92057826179 41.4783049128831 -4.31359426663112 2.16189726676238e-05 RBFA other 1.64604578153553e-13 0.315433611761447 1 3.71357964431988 -4.31359426663112 2.7270791648664e-48 891.470099687359 49.295639962557 18.0841571458345 1.8177162794355e-49 650.963002579664 213.71020861111 3.04600798815476 0.00253225039858183 USP14 other 4.17761257265883e-44 1 2.78619551311873e-45 18.0841571458345 3.04600798815476 2.6377625839418e-64 1401.34604268922 64.6538882949674 21.6745826066319 1.7984108225867e-64 258.031608260312 269.180075987664 0.958583607325146 0.338501386374493 VAPA other 4.04949311886745e-60 1 2.76110013591735e-60 21.6745826066319 0.958583607325146 1.16714940442513e-28 117.767159715282 9.28580809386694 12.6824890763212 9.10685359645298e-30 78.1959717175989 43.3269470373707 1.80478840685804 0.0721171806534577 METTL4 other 1.7584272927069e-24 1 1.38269358154946e-25 12.6824890763212 1.80478840685804 7.41193501533877e-11 157.217265740494 23.5961271593631 6.66284194345466 1.29027871811137e-10 -147.829590028338 109.477826056651 -1.35031535931159 0.17793603179926 LPIN2 other 9.31161395977009e-07 1 1.74987599750263e-06 6.66284194345466 -1.35031535931159 4.4332658616669e-32 533.367821112347 39.1643739318632 13.6186990258106 3.43181958499814e-33 329.792208274633 181.243518488649 1.81960828737325 0.0698185998103043 SMCHD1 other 6.71817108677002e-28 1 5.22563168207666e-29 13.6186990258106 1.81960828737325 0.461429797048846 -97.072997347942 95.4590534369907 -1.01690718536212 0.310019719729081 240.773225813625 442.896818495933 0.543632773500802 0.587099294995342 MYOM1 other 1 1 1 -1.01690718536212 0.543632773500802 9.03753308009463e-37 1783.29310698728 123.250857690102 14.4688089024997 2.34559157119644e-36 -596.004937518067 571.46040557759 -1.04295053813163 0.297810907376305 MYL12A other 1.37713929074482e-32 1 3.58007641511713e-32 14.4688089024997 -1.04295053813163 6.02507027378767e-37 112.300905998318 7.54685579776137 14.8804891742638 4.38795387802057e-38 80.5378278085056 31.9314883393832 2.52220713774789 0.0121675762426158 CEP76 other 9.18280960427978e-33 1 6.70347713945202e-34 14.8804891742638 2.52220713774789 2.97495079190978e-28 358.810863758738 28.7865621711075 12.464526386512 4.3820959602981e-29 126.66259437841 120.938667057531 1.04732917486312 0.295779760628163 CEP192 essential 4.47908591229936e-24 1 6.64676315258016e-25 12.464526386512 1.04732917486312 1.31965189932817e-51 529.384089408663 28.2769318136862 18.7214119585788 1.88613039162922e-52 194.438829566723 119.658541071591 1.62494735290473 0.105216905987458 RNMT essential 2.02315832686001e-47 1 2.8929467946809e-48 18.7214119585788 1.62494735290473 7.25558464484281e-07 101.893713496669 35.9640754984072 2.83320819691812 0.0049045433001199 -108.479338215105 56.6132338355431 -1.91614806054409 0.0562482446114143 SMAD7 other 0.00758426262925419 1 1 2.83320819691812 -1.91614806054409 0.338021176355946 48.6238516215843 61.3155756130149 0.793009788058865 0.428363374653226 -47.3407872316766 96.4395950729014 -0.490885379556917 0.623846095770154 LIPG other 1 1 1 0.793009788058865 -0.490885379556917 6.83338177901825e-19 559.239526432697 57.1346927549526 9.78809020346434 6.31202093424591e-20 356.386296854283 254.723086849409 1.39911266490335 0.162763092056228 LAMA1 other 9.82571966005034e-15 1 9.36956387479463e-16 9.78809020346434 1.39911266490335 0.00955756115090348 52.6916027922571 21.0725428013143 2.50048621512211 0.0129052929968374 -1.92749161627224 37.6459572988359 -0.051200494145273 0.959197903811005 RNF125 other 1 1 1 2.50048621512211 -0.051200494145273 1.99043352975136e-34 363.446391499192 25.8552287348059 14.0569783863457 3.21267778533597e-35 132.13274480233 109.104947670201 1.21106097957846 0.226774116192303 ANKRD12 other 3.02525992186909e-30 1 4.90029742597296e-31 14.0569783863457 1.21106097957846 1.56555235767245e-14 51.656347401012 12.1731489412362 4.24346630854301 2.88850829561691e-05 -59.6153069520433 18.928912337341 -3.1494311923269 0.00179071862289414 POLI other 2.13478719492216e-10 1 0.313923081567646 4.24346630854301 -3.1494311923269 1.35361801495602e-08 508.066660325811 88.9328056790586 5.71292737754531 3.15797369090721e-08 -13.8337189991626 204.926539446856 -0.0675057463835723 0.946233260983884 MIB1 other 0.000156072157124429 1 0.000400841600586852 5.71292737754531 -0.0675057463835723 1.27189536471756e-15 664.096798662039 99.0854938915081 6.7022605689303 1.15892566153077e-10 -467.912926715557 219.419943096234 -2.13249953542435 0.0338516456502447 RIOK3 other 1.76475481854561e-11 1 1.57300980039571e-06 6.7022605689303 -2.13249953542435 0.0505791386384707 87.4024678419247 51.8609466916756 1.68532341612564 0.0929010427723561 -185.805899975399 126.215750122958 -1.472129269084 0.141968768813686 EEA1 other 1 1 1 1.68532341612564 -1.472129269084 0.532538046427184 -5.7709516733965 8.96783284068399 -0.643516864767558 0.520354035923441 -18.5830995080982 16.8489843825828 -1.10292104771062 0.270898043373066 RUBCNL other 1 1 1 -0.643516864767558 -1.10292104771062 0.737235135084976 -2.9011815940838 7.51210065879464 -0.386201107500776 0.699608455338642 -13.0950152013147 17.4412369852459 -0.750807710049017 0.45332888180987 NALCN other 1 1 1 -0.386201107500776 -0.750807710049017 0.314762341352229 -0.796945045592332 18.0844069706014 -0.0440680773711779 0.96487788418844 61.6078015912084 41.8762474782679 1.47118725533324 0.142232443366683 FGF14 other 1 1 1 -0.0440680773711779 1.47118725533324 5.49389078005788e-19 770.744774700766 95.7636287850949 8.04840819504042 2.1535204136568e-14 -608.027655046198 192.22007447241 -3.16318499363327 0.00172556402649795 NDFIP2 other 7.90735699973731e-15 1 3.08664080889429e-10 8.04840819504042 -3.16318499363327 0.454466284099967 -3.95686110326789 11.6316335439347 -0.340181032038376 0.733946218830433 -34.7154703981405 27.6242182100634 -1.25670417653643 0.209788928101351 TNFSF13B other 1 1 1 -0.340181032038376 -1.25670417653643 1.01994985306082e-06 181.205620952852 40.9921318796689 4.42049760877954 1.35299077171206e-05 -78.3465177537101 76.359718610278 -1.02601894270423 0.305662477176478 FNDC3A other 0.0105554610293264 1 0.150439043906664 4.42049760877954 -1.02601894270423 5.42674796111433e-09 23.2505927226741 4.5718530837579 5.08559489920505 6.27297609246474e-07 -12.6477979610773 8.49878718868999 -1.48818857094206 0.13769212590683 CDADC1 other 6.3791422282899e-05 1 0.00754952672728132 5.08559489920505 -1.48818857094206 0.00320414393404908 9.68002285604471 11.0602242652336 0.875210359565002 0.38212001670668 -55.2698153744307 20.5602609198768 -2.6881864772931 0.00756249538456039 CAB39L other 1 1 1 0.875210359565002 -2.6881864772931 0.0855704626752793 812.423077668012 381.050087750066 2.13206374643558 0.0338247457724624 -45.3515416767531 792.234525586121 -0.0572450962588389 0.954388578885377 KLF5 other 1 1 1 2.13206374643558 -0.0572450962588389 2.75681186414268e-37 1423.74594389539 108.525654788917 13.1189804536502 1.19421519558581e-31 -947.24698021519 252.494772792423 -3.75155085287221 0.000209264717891886 STK24 other 4.20248400569911e-33 1 1.8169984200838e-27 13.1189804536502 -3.75155085287221 0.451768782465721 -175.684143970545 198.399184820661 -0.885508396263582 0.376553697806299 -477.15480962786 421.926859910118 -1.13089460512068 0.258954309955974 ACP5 other 1 1 1 -0.885508396263582 -1.13089460512068 1.37590362534755e-12 361.408552380527 48.0322735923069 7.52428576352906 5.67303967436432e-13 11.497407832789 111.829039152969 0.102812363585293 0.918177730585616 DNAJC3 other 1.80752459261907e-08 1 7.98253412579803e-09 7.52428576352906 0.102812363585293 6.75033096975076e-08 60.6879722612732 11.0381019609915 5.49804418148552 7.98064388574868e-08 -19.6550286904484 25.69897787574 -0.764817526420103 0.444956453992139 UGGT2 other 0.000750906817075074 1 0.000997261259963156 5.49804418148552 -0.764817526420103 4.36059839142456e-22 237.580060235207 23.3277957896117 10.1844195815966 2.97694588454974e-21 -56.3222355011352 57.1169378800421 -0.986086397338458 0.324845129433942 ARHGEF7 other 6.41182387475067e-18 1 4.44190095433667e-17 10.1844195815966 -0.986086397338458 0.255259725223725 27.8066267402971 17.61377288445 1.5786865723042 0.115408432938416 33.5879371309254 28.6117227672166 1.17392222076926 0.241310161361635 SGCG other 1 1 1 1.5786865723042 1.17392222076926 2.0492275054807e-06 54.6021818304876 83.8271509937027 0.651366307732317 0.515277546822823 -597.028965434944 137.196913833051 -4.35162095673261 1.82006242772075e-05 PARP4 other 0.0206664593927728 0.266165929429882 1 0.651366307732317 -4.35162095673261 2.02019746823434e-19 153.914194659913 23.6515124892977 6.50758359447662 2.96922245476978e-10 -155.451797350108 41.5404503508477 -3.7421789132562 0.000216420118601129 SUPT20H other 2.91676110463674e-15 1 3.99805803534751e-06 6.50758359447662 -3.7421789132562 3.20291142220798e-20 65.3131963550723 10.7527261308837 6.0741058183823 3.55653756496155e-09 -88.8085328024403 19.467929621275 -4.56178620583199 7.25114208423809e-06 MRPS31 essential 4.65511146103708e-16 0.107106619726281 4.6615537863951e-05 6.0741058183823 -4.56178620583199 1.80429928124478e-07 26.7860403935704 6.69062940388575 4.00351577954889 7.7725880760229e-05 -22.2039570345459 12.1134585565955 -1.83299896811522 0.0677374662804892 SLC25A15 other 0.0019621754683537 1 0.814878133890241 4.00351577954889 -1.83299896811522 3.45279361819837e-17 397.688491896375 52.4885222400558 7.57667533632496 3.87461826554127e-13 -182.29428355227 97.4170605772795 -1.87127678121286 0.0622218946864076 KPNA3 other 4.87638042698155e-13 1 5.46669891085218e-09 7.57667533632496 -1.87127678121286 0.483726647810266 -35.4054340856163 50.7847369457964 -0.697166830329461 0.486207748182401 49.5483314213693 83.4925833197263 0.593445902034544 0.553304630616304 FLT1 other 1 1 1 -0.697166830329461 0.593445902034544 0.703834665233804 -23.3724508096984 89.6567693866096 -0.260688077092249 0.794501790880909 -138.331642035875 166.333190640495 -0.831653871985534 0.406228394349543 RGCC other 1 1 1 -0.260688077092249 -0.831653871985534 1.1497871449412e-10 212.814974810678 41.4296417194918 5.13678047837313 4.87551601506082e-07 -167.159484401072 77.4141532682658 -2.15928841618675 0.03157287393636 DGKH other 1.43378456974168e-06 1 0.00589596151701305 5.13678047837313 -2.15928841618675 2.08414479262054e-09 58.8715231115728 15.5740133405552 3.78011253902484 0.000187074752450224 -90.4813889118959 27.0078053311073 -3.35019405696325 0.000904440798809192 KATNAL1 other 2.48888571134745e-05 1 1 3.78011253902484 -3.35019405696325 3.01120925698097e-15 209.985183974625 30.2975493023376 6.93076465951731 2.35954707558842e-11 -119.3341935693 56.0105808854466 -2.13056518398485 0.0338969084467586 INTS6 other 4.15275868630246e-11 1 3.24154577244337e-07 6.93076465951731 -2.13056518398485 5.0080659669829e-12 36.7750705237609 6.90397893153386 5.32664871785618 1.9040020487918e-07 -36.9403293601867 12.7632722540453 -2.89426791381642 0.00406480018615747 DHRS12 other 6.49395913938672e-08 1 0.00234363612185783 5.32664871785618 -2.89426791381642 0.61510372055623 28.1623331455637 35.4089240793534 0.795345633277371 0.4270038615101 52.8904918343097 61.6611217225224 0.857760779512237 0.39166855219007 MEDAG other 1 1 1 0.795345633277371 0.857760779512237 0.0161245976370048 1031.44886063033 430.32133956425 2.39692705380308 0.0171101076031602 -388.559526850385 800.364927522989 -0.485477953229309 0.627671653212126 TSC22D1 other 1 1 1 2.39692705380308 -0.485477953229309 1.67598713261583e-12 151.34163340354 24.3849685512921 6.206349337101 1.84073273365772e-09 -136.929243284139 49.9296458220516 -2.74244371314293 0.00647249291715784 CLN5 other 2.19738672957262e-08 1 2.43234423425531e-05 6.206349337101 -2.74244371314293 0.410455686896232 -21.1397183485364 287.08284711038 -0.0736362989336262 0.941346523946151 -678.807978267562 534.49779464762 -1.26999210298909 0.205024768514736 OLFM4 other 1 1 1 -0.0736362989336262 -1.26999210298909 0.328117728384036 160.544113906341 283.773401317114 0.565747575922151 0.571964362655513 -879.11621191181 766.052646731584 -1.1475924215687 0.251999478992025 MSLN other 1 1 1 0.565747575922151 -1.1475924215687 3.47844460816642e-07 100.879949496721 32.6732505095474 3.08753943741358 0.00219594828001184 -351.606345430953 96.1356896531802 -3.65739660993134 0.000298092200898051 MGRN1 other 0.0037268055531895 1 1 3.08753943741358 -3.65739660993134 0.00245356733116183 103.794474595458 31.0165081984362 3.34642681024589 0.000918333107862875 -3.86970877449967 106.733217938512 -0.0362558990466208 0.971101425605126 ZNF629 other 1 1 1 3.34642681024589 -0.0362558990466208 0.000360558742092418 38.3611546860147 23.9449398653645 1.60205683963745 0.110132762443522 -175.6394305356 64.5012707244964 -2.72303829928881 0.00682440058512543 TRADD other 1 1 1 1.60205683963745 -2.72303829928881 0.289210526731647 19.057090178706 12.0782936104827 1.5777965657472 0.115603449038367 22.0898728561462 32.5356960777585 0.678942685085104 0.497666458170229 HSF4 other 1 1 1 1.5777965657472 0.678942685085104 0.0148680297102989 -316.932789317917 109.626367874346 -2.89102699891678 0.00410756893090429 -460.150346664751 377.359985771806 -1.21939358706413 0.223610016123799 CORO1A other 1 1 1 -2.89102699891678 -1.21939358706413 6.61847777246594e-07 160.256182862852 43.1639176252561 3.71273488783333 0.000242283890069561 -435.433273529702 154.574464706489 -2.81698063361575 0.00515280135719446 MAPK3 other 0.00693484100998982 1 1 3.71273488783333 -2.81698063361575 0.0897772639660593 18.4334249313015 24.4503927154918 0.753911200764559 0.451463936459581 -156.030549057904 87.5593915888947 -1.78199672503998 0.0757099245856941 GDPD3 other 1 1 1 0.753911200764559 -1.78199672503998 2.76543204105838e-09 162.274486468937 52.4790849280339 3.09217446705614 0.00216294243049866 -552.895472269501 140.470665860493 -3.93602086871721 0.000101799209356561 ELMO3 other 3.28948141283895e-05 1 1 3.09217446705614 -3.93602086871721 1.20435076245712e-08 175.217462469587 50.2215319100225 3.48889123461046 0.000555736706057828 -405.263061485713 135.179211050724 -2.99796883215752 0.00293918605316647 PHKB other 0.000139186817617169 1 1 3.48889123461046 -2.99796883215752 0.0185189795021807 32.9233393521752 17.9757884902878 1.83153798065456 0.0679526941957807 -88.5005104694396 55.3757508994508 -1.59818167757464 0.110992554877188 LYRM1 other 1 1 1 1.83153798065456 -1.59818167757464 7.76217698568154e-14 403.742792994619 77.2739414097476 5.22482463853836 3.15468352964477e-07 -740.613110390066 206.855906719199 -3.58033339311614 0.00039656482521486 NUTF2 essential 1.04548761820145e-09 1 0.00384619015934291 5.22482463853836 -3.58033339311614 9.38879871845262e-12 297.427216407573 52.1223086707951 5.70633235542434 2.63137837741911e-08 -223.550147638991 137.93644484078 -1.62067499925081 0.106072297463889 NUP93 essential 1.20786895512893e-07 1 0.000335369174202066 5.70633235542434 -1.62067499925081 3.23412014606224e-06 98.7177594727092 30.1206159260479 3.27741503411089 0.00116309818901698 -182.58049388673 80.6303807552055 -2.26441314274636 0.0242196090059865 CENPT essential 0.0321697930928811 1 1 3.27741503411089 -2.26441314274636 0.000609868560800881 9.61879721583516 4.30681469593484 2.2333900794279 0.0262163328520249 -23.04532856942 11.5289843218324 -1.99890362638269 0.0464669245784275 TSNAXIP1 other 1 1 1 2.2333900794279 -1.99890362638269 5.04150054843722e-10 288.583567898983 52.2526836286436 5.52284682543633 6.91196983986349e-08 -201.092967797831 142.531429975134 -1.41086753870998 0.159255085499175 NFAT5 other 6.16978837117747e-06 1 0.000866000701236496 5.52284682543633 -1.41086753870998 1.55078212788347e-15 326.759789216222 55.0465228592116 5.93606593557145 7.76829027214174e-09 -428.676736085403 146.915168131502 -2.91785212879925 0.00378049602219123 LONP2 other 2.14953910745928e-11 1 0.00010072365166859 5.93606593557145 -2.91785212879925 2.81543041765947e-18 468.751871484825 88.7732345878753 5.28032884755162 2.41734525024487e-07 -1105.87560675184 237.696076518307 -4.65247732714116 4.84732973216997e-06 N4BP1 other 4.02578395421128e-14 0.071895594587545 0.00296342354227518 5.28032884755162 -4.65247732714116 3.1854770820604e-14 268.065171544897 47.7070828469376 5.61898056950896 4.1798836946945e-08 -369.029745391596 126.746987885269 -2.91154647182337 0.00384896460544965 ARL2BP other 4.31791418473287e-10 1 0.00052812830482465 5.61898056950896 -2.91154647182337 5.97270047895072e-10 255.816660404577 58.211897996454 4.39457686846356 1.51160381404998e-05 -400.655459365885 154.655918782691 -2.59062480453044 0.010018660982006 PLLP other 7.28251369398461e-06 1 0.167515934673019 4.39457686846356 -2.59062480453044 0.0491724160728395 20.0470041084524 9.76664412190936 2.05259901540605 0.0409426687516899 56.5944803689189 26.1508212391476 2.16415690548935 0.0312082909009557 ZNF423 other 1 1 1 2.05259901540605 2.16415690548935 0.689512483961363 20.4050706248197 24.1119398673545 0.846264163608272 0.398037781141348 33.9762644182991 64.0600004838506 0.530381894500054 0.596215026074645 CCL22 other 1 1 1 0.846264163608272 0.530381894500054 1.27397547264392e-05 27.9087606946439 8.62141689994296 3.23714315390879 0.0013338274923386 -45.9179078568925 23.6598186422557 -1.94075485324661 0.0531659698906359 DHODH essential 0.120518079712115 1 1 3.23714315390879 -1.94075485324661 0.667233034790746 1.68620818048181 2.30781930721759 0.730650001587332 0.465527566117166 4.87765530733766 6.11262117634346 0.797964599248313 0.425482788977915 CCL17 other 1 1 1 0.730650001587332 0.797964599248313 0.00759791382391008 95.3297948639678 39.9460068834976 2.38646619027521 0.0175937939856673 -96.2514449570516 106.932134209152 -0.900117122592824 0.368736920765907 CTCF other 1 1 1 2.38646619027521 -0.900117122592824 0.000271157487201434 59.80646082491 20.3587974326148 2.93762247121236 0.00354822997562072 -77.3414015686775 54.4988054938896 -1.41913938971284 0.156834734613477 ACD other 1 1 1 2.93762247121236 -1.41913938971284 1.76480699570144e-17 268.916063053315 40.8543180540345 6.58231677487905 1.89555183584619e-10 -317.217682559078 107.540584127438 -2.94974855430547 0.00341474820919036 POLR2C essential 2.50320224270292e-13 1 2.56164875096254e-06 6.58231677487905 -2.94974855430547 0.158979138560437 -4.31872319683313 5.01826076613874 -0.860601590490112 0.390103860231359 16.3743695665374 13.433466211186 1.21892364257428 0.223773769968471 PARD6A other 1 1 1 -0.860601590490112 1.21892364257428 0.230014120969434 9.47994152996594 6.6770930837902 1.41977076116853 0.156647873400156 26.7804252771434 18.3559664081725 1.45894935094347 0.145559911617142 ZNF821 other 1 1 1 1.41977076116853 1.45894935094347 0.000853028073693409 124.85026631339 44.8122490246532 2.78607454503577 0.00565433776238123 -128.670631723968 118.424157062055 -1.08652351780341 0.278067764021966 MMP15 other 1 1 1 2.78607454503577 -1.08652351780341 1.45080753763236e-18 563.697434809449 87.7997155086782 6.42026493529734 4.92733882834894e-10 -848.138008134297 232.026009087009 -3.65535748113587 0.000300231077825553 USB1 other 2.0792973629347e-14 1 6.60608316716742e-06 6.42026493529734 -3.65535748113587 5.14682008448062e-11 306.302201366437 63.3237892364408 4.83707947771025 2.0566846751214e-06 -503.838543791916 172.70043399604 -2.91741330426227 0.00378075759226473 CYB5B other 6.49991908469058e-07 1 0.0240920042843721 4.83707947771025 -2.91741330426227 0.0993438300580977 13.6480268562577 16.196757931528 0.842639429073086 0.400061460459074 -60.2496481324033 42.8027480639086 -1.40761168050343 0.160219761945802 CCDC113 other 1 1 1 0.842639429073086 -1.40761168050343 0.0358538347518856 3.22381331423386 2.25302630095765 1.43088134961566 0.153443081063798 -7.78002572475154 5.95401360870696 -1.30668591576181 0.192260637656155 PRSS54 other 1 1 1 1.43088134961566 -1.30668591576181 0.00017053493548567 171.267025440314 44.8705554051885 3.81691342783133 0.00016222195404982 -82.8501956947161 126.545896409735 -0.654704720147233 0.513128185210278 NME3 other 1 1 1 3.81691342783133 -0.654704720147233 0.000600008261326344 375.539974028289 108.254864592602 3.46903555273538 0.000594116410217369 -22.8480870835278 287.273659315474 -0.0795342223090384 0.936657582054257 NDRG4 other 1 1 1 3.46903555273538 -0.0795342223090384 1.07152076421699e-20 479.406205099442 75.5801753102634 6.3430152567315 7.6799721213e-10 -891.298848789461 199.31039908931 -4.47191342178827 1.07805492487511e-05 PSMD7 essential 1.56302733876332e-16 0.158538757252134 1.02535307791476e-05 6.3430152567315 -4.47191342178827 9.36961282658372e-06 95.3480517166442 38.6305136930956 2.46820563853092 0.0141033356665497 -279.62765528357 102.512982410682 -2.7277291978819 0.00673033231019716 SETD6 other 0.0896297162990999 1 1 2.46820563853092 -2.7277291978819 2.56570218620305e-17 123.621528579015 24.0385248014787 5.14264205478244 4.73708996946775e-07 -295.990680311843 63.1832954284084 -4.68463504957926 4.15757449881937e-06 SLC38A7 other 3.63098173391455e-13 0.0617358237329688 0.00573187886305598 5.14264205478244 -4.68463504957926 1.81038797580343e-18 280.749661631748 35.6308301376974 7.87940276852307 5.19180134997917e-14 -187.199517845143 97.9525540374246 -1.91112441819149 0.056881828575678 VAC14 other 2.59247558135052e-14 1 7.41441150790526e-10 7.87940276852307 -1.91112441819149 5.56073675299089e-05 1464.85348897465 437.42951857586 3.34877603538 0.000908922597920727 -1709.42406216149 1193.12237915591 -1.43273153871344 0.152913805049494 HAS3 other 0.493459779460411 1 1 3.34877603538 -1.43273153871344 6.40609622632121e-18 95.8321478005742 12.5801756078991 7.61771145232673 2.96255189727781e-13 -72.9943831934031 33.8909582578095 -2.15380110052164 0.0320046175727674 TANGO6 essential 9.12740590326247e-14 1 4.18638208604328e-09 7.61771145232673 -2.15380110052164 3.77654214029821e-14 238.409185784285 42.6736567571596 5.58680000500041 4.95002829714779e-08 -393.078839967498 116.402391178466 -3.37689660829077 0.000823500179030576 COG4 essential 5.1111721326796e-10 1 0.000623852066289536 5.58680000500041 -3.37689660829077 0.045281276176594 35.56823452371 18.9622675974088 1.87573740012879 0.0616044626482903 -37.7222326166126 50.760411411075 -0.743142767522612 0.45794218192439 SMPD3 other 1 1 1 1.87573740012879 -0.743142767522612 4.81714542999606e-10 127.203414393168 25.142226690638 5.05935357111918 7.11547054536333e-07 -138.028006864674 67.3036473117643 -2.05082506487798 0.0411006210037908 SLC7A6OS essential 5.89955800811617e-06 1 0.0085328722779997 5.05935357111918 -2.05082506487798 4.91671681120284e-08 161.612243826142 35.6492802375767 4.53339429994417 8.22113838027299e-06 -160.173429858926 95.4301547571966 -1.678436237125 0.0942412610711033 SLC7A6 other 0.000551163954535838 1 0.0928413157284228 4.53339429994417 -1.678436237125 1.10489723696779e-07 90.8300549972677 18.8252320792586 4.82491023828295 2.17431148536571e-06 -49.2532262273448 50.3935787396395 -0.977371075029492 0.329126081250864 PLA2G15 other 0.00121616038873044 1 0.0254329214443227 4.82491023828295 -0.977371075029492 0.0614392553262044 3.99288952468828 19.044593136237 0.209660006707669 0.834066457591921 110.892796670762 50.0616279161815 2.21512566184285 0.0274552992043949 FA2H other 1 1 1 0.209660006707669 2.21512566184285 1.79055987981145e-13 115.599292918309 21.1416804607075 5.46783843096836 9.18941546379136e-08 -162.043691783553 55.3950150324603 -2.92523960303284 0.0036878402976825 WDR59 other 2.39523195122378e-09 1 0.0011461957907987 5.46783843096836 -2.92523960303284 4.47023376046565e-10 138.932638203686 35.2050977714726 3.94637842239613 9.76320454506581e-05 -286.077194439471 91.1999726569363 -3.13681228299922 0.0018671597251845 MON1B other 5.48005956695484e-06 1 1 3.94637842239613 -3.13681228299922 0.00764704151359744 52.2310965454142 25.9516767821066 2.01262897129741 0.0449936969498 -81.5216616250356 66.293226443989 -1.22971329045077 0.219710662346497 CMC2 other 1 1 1 2.01262897129741 -1.22971329045077 3.04998286221277e-12 217.470201295811 37.1054459976039 5.86087016202025 1.16071075750882e-08 -282.67018144076 100.101278707937 -2.82384186385371 0.00504744513310051 AXIN1 ts 3.97168768317346e-08 1 0.000149627223750462 5.86087016202025 -2.82384186385371 9.67024552397237e-05 215.413821459039 56.0361387357574 3.84419459154456 0.000145991452054589 -146.786746670074 161.015139264712 -0.911633200085327 0.362650224461479 HCFC1R1 other 0.834638891174055 1 1 3.84419459154456 -0.911633200085327 1.31548665153429e-09 273.453489846435 47.1252634038977 5.80269414099058 1.59422005395932e-08 -157.743498232096 127.108563887736 -1.24101392862417 0.215526958750366 NPRL3 other 1.58253044179576e-05 1 0.000204789286876894 5.80269414099058 -1.24101392862417 0.000375655332282351 36.0179914455576 11.6650444635686 3.08768573990836 0.00219376324879516 -26.9337966989675 30.2824919832453 -0.889418107131654 0.374446543228017 MLYCD other 1 1 1 3.08768573990836 -0.889418107131654 7.59957053320697e-05 155.629430927811 42.5292321283541 3.65935200659438 0.00029649642020283 -143.020939654949 114.711923682026 -1.24678355191213 0.213406102083887 MPG other 0.663548695210826 1 1 3.65935200659438 -1.24678355191213 0.333137042431237 6.78684754469082 6.14382876129718 1.10466092210192 0.270136446046766 -6.08742466258045 15.949398717808 -0.381671106872741 0.702958646053188 NECAB2 other 1 1 1 1.10466092210192 -0.381671106872741 6.314063098307e-05 46.0952312036362 13.7500396645339 3.35237078061176 0.000897289526502036 -39.0331175935451 35.3437975534237 -1.10438380410438 0.270256404229287 HSDL1 other 0.556079537067897 1 1 3.35237078061176 -1.10438380410438 0.000126607884030846 77.1260504841769 30.1080654539576 2.56164085341588 0.0108757677797356 -147.764398288604 77.3912945774749 -1.90931549982899 0.0571155421938906 TAF1C essential 1 1 1 2.56164085341588 -1.90931549982899 0.000693640124772813 18.3994856443504 10.9203391924932 1.68488224770513 0.0929892909740297 -93.3910674120138 32.2570561488189 -2.89521359237344 0.00405037072354312 NAGPA other 1 1 1 1.68488224770513 -2.89521359237344 0.632553058890792 -1.61065912478759 5.59001131773653 -0.288131639318356 0.773432504364971 9.81090916661773 14.3688478837653 0.682790244978694 0.495233390988562 WFDC1 other 1 1 1 -0.288131639318356 0.682790244978694 0.561513624884512 4.82154394901648 6.65466791175044 0.724535621154418 0.469268032084954 -11.2528458492421 19.6568982608743 -0.572462944046476 0.567411613308973 SEC14L5 other 1 1 1 0.724535621154418 -0.572462944046476 0.818406356472115 32.6622744310646 161.379397912745 0.202394325753554 0.839737079535389 -183.606888185244 414.817768404948 -0.442620596729129 0.658339217217746 COTL1 other 1 1 1 0.202394325753554 -0.442620596729129 1.06957097691676e-17 299.612620702275 52.4897528490017 5.70802117442192 2.60780031391626e-08 -547.376231809694 134.488983639894 -4.0700451218766 5.9276063007881e-05 USP10 essential 1.52071601498025e-13 0.852686166368369 0.000332416306014906 5.70802117442192 -4.0700451218766 0.0283055799566148 254.442865290796 95.8147111533869 2.65557201214608 0.00831375825712714 382.914878513233 245.495976287763 1.55976030362466 0.119804938585834 CRISPLD2 other 1 1 1 2.65557201214608 1.55976030362466 0.0029286331497952 73.2465263508971 92.5512917842014 0.791415494466392 0.429289619221162 -787.495558553245 262.930273981969 -2.99507373809396 0.00295858942274383 TSC2 ts 1 1 1 0.791415494466392 -2.99507373809396 0.000403907249917029 24.183414007889 9.08820319083248 2.66096757522801 0.00818709088573218 -58.1933078704888 26.8363430070767 -2.16845148592501 0.0308654363479947 ZNF500 other 1 1 1 2.66096757522801 -2.16845148592501 9.02581724587371e-09 441.442655430491 70.5623184137312 6.25606790358219 1.28227377444692e-09 287.563554371968 190.394826989805 1.51035382062857 0.131952438478385 NME4 other 0.000105006357838495 1 1.7017055260685e-05 6.25606790358219 1.51035382062857 0.0242391008576735 1231.99879335321 449.208955551051 2.74259624196918 0.00643879489926353 1197.6188917434 1390.73990463486 0.86113793654166 0.389806855063861 ABCC1 other 1 1 1 2.74259624196918 0.86113793654166 0.151487340771925 122.242936874148 81.4937313228623 1.50002871251343 0.134592912552969 -190.754260634809 252.302592652598 -0.756053509515312 0.450173314095013 NOMO3 other 1 1 1 1.50002871251343 -0.756053509515312 0.385810476344542 18.9820483885337 18.3870290928226 1.03236081765614 0.302687612481298 -27.8480953855684 49.640846344461 -0.560991551036996 0.575198369175683 LMF1 other 1 1 1 1.03236081765614 -0.560991551036996 0.124069182501698 -3.03863988110883 6.69996158466375 -0.453530940843644 0.650473869883856 27.0116395874713 17.1077486289658 1.57891258360769 0.115344067307221 FOXF1 other 1 1 1 -0.453530940843644 1.57891258360769 0.0045144858478201 63.7761045964437 28.6889152854446 2.22302251451106 0.0269169673778535 -129.223506784582 77.4463687726451 -1.66855475385729 0.0961898901563022 NARFL essential 1 1 1 2.22302251451106 -1.66855475385729 1.30325891813083e-10 46.6909632722253 11.0548143549023 4.22358637361651 3.13819903273121e-05 -86.6061335627724 28.2274730584208 -3.06815042861005 0.00233792264646571 MTHFSD other 1.62307865664014e-06 1 0.340118011167409 4.22358637361651 -3.06815042861005 2.7756554046875e-08 228.116906469128 55.0828893080378 4.14133879567281 4.4223970396799e-05 -466.383182663481 154.222705387719 -3.02408897244399 0.00269561843438463 CLCN7 other 0.000315286697418453 1 0.474169410594479 4.14133879567281 -3.02408897244399 0.119846760552982 21.4611642459237 16.2257555563474 1.32266039454343 0.186898738198038 -48.7143360833428 43.8017902011524 -1.11215399780763 0.266912009121143 HAGHL other 1 1 1 1.32266039454343 -1.11215399780763 0.404129421176443 0.73988248162175 16.0494217993027 0.0461002577459766 0.963259277020379 -55.0155800880119 43.3257732782651 -1.26981184466501 0.205080068627816 FAM173A other 1 1 1 0.0461002577459766 -1.26981184466501 3.90190896013071e-09 3552.06884870411 1099.59189961114 3.23035196054122 0.00136488377308111 -9817.31908200367 2807.40476788252 -3.49693752547423 0.000537160880275119 SLC7A5 essential 4.6147877271466e-05 1 1 3.23035196054122 -3.49693752547423 2.13996825259666e-05 186.12057716277 41.2484253091019 4.51218624148789 9.04230931451942e-06 6.58156829660478 111.351047120292 0.0591064787158645 0.952904423886995 METRN other 0.198182459872977 1 0.101888741356005 4.51218624148789 0.0591064787158645 7.25589804132132e-07 55.7525863826547 15.1413922646294 3.68213077161298 0.000271409073429914 -73.7402296271316 38.6621817875464 -1.90729612809602 0.0573773939944962 FBXO31 other 0.00758426262925419 1 1 3.68213077161298 -1.90729612809602 0.00137031890314473 414.835703202501 130.738918303498 3.17300853170209 0.00165606068322554 -279.98884310251 352.932635449152 -0.793320920141569 0.428182390963221 STUB1 other 1 1 1 3.17300853170209 -0.793320920141569 0.0561697091590247 18.1751456261287 10.5963033102485 1.71523455812652 0.0872763520103468 -31.2900369400002 28.6049578949632 -1.09386761046447 0.274840934573332 RHBDL1 other 1 1 1 1.71523455812652 -1.09386761046447 0.0192684634505953 0.805849755861711 14.806878162942 0.0544240147716319 0.956631414450727 -130.981497640732 48.0253240438551 -2.72734229801603 0.00673804641134567 NUBP1 essential 1 1 1 0.0544240147716319 -2.72734229801603 9.04379335606116e-10 268.958554156495 62.6579412869042 4.29248948549014 2.34455892252212e-05 -609.549688463073 171.162012082127 -3.56124399946057 0.000425162489610243 UBE2I essential 1.09538425128613e-05 1 0.256377518177793 4.29248948549014 -3.56124399946057 0.00879098204520328 3.52873809506774 7.04232398836156 0.501075795561165 0.616662278212544 -56.8932249351068 20.2384804080906 -2.81114114241319 0.00524098390117584 MEFV other 1 1 1 0.501075795561165 -2.81114114241319 0.654502902756202 0.0530269286199394 18.9236212849131 0.00280215545542624 0.997765952389034 -51.701951029793 58.3175159838696 -0.886559555178817 0.375981857105831 CRYM other 1 1 1 0.00280215545542624 -0.886559555178817 1.78506974783944e-09 195.977214165835 47.6603481153287 4.11195515592141 5.0034032952933e-05 -465.518621311202 128.623179008352 -3.61924363011564 0.000343785007775443 CAPN15 other 2.13672848816381e-05 1 0.533763063541889 4.11195515592141 -3.61924363011564 1.08877155489171e-11 599.815662399063 99.6635617370931 6.01840484069136 4.81996223646527e-09 -870.532518874212 323.381252015068 -2.69196965949544 0.00747678998306433 GSPT1 essential 1.39885369372487e-07 1 6.29246069970542e-05 6.01840484069136 -2.69196965949544 0.000179720550457283 31.0739565967758 7.73327616834778 4.01821374541895 7.31560648565889e-05 -2.81168224492627 22.2241632850342 -0.126514650241958 0.899404007655765 ZNF174 other 1 1 0.769455490161602 4.01821374541895 -0.126514650241958 0.253099216909663 41.3444225738342 26.4633733837482 1.56232623763775 0.119199532006427 -9.35842323735822 76.0513808572416 -0.123053955521534 0.902141621168473 CLUAP1 other 1 1 1 1.56232623763775 -0.123053955521534 0.000212662289990516 118.733866515677 44.803699037974 2.65009070824805 0.00845067300831278 -343.876917282591 142.902502645348 -2.40637435256132 0.0166836201110992 UBFD1 other 1 1 1 2.65009070824805 -2.40637435256132 1.16239730171945e-07 97.8409370797648 22.5381481945277 4.3411258207771 1.90924574677171e-05 -184.301757782879 71.8859793085375 -2.56380673332485 0.0108138824956182 EARS2 essential 0.00127805583324054 1 0.210150679347162 4.3411258207771 -2.56380673332485 0.231927350248382 362.983317337495 218.051660708434 1.66466660312601 0.0969580663493503 44.5794571524259 624.453862272035 0.0713895130542174 0.943132351556356 ELOB other 1 1 1 1.66466660312601 0.0713895130542174 0.104494702055711 -222.624581930959 133.31242715658 -1.66994620591131 0.0959139915350814 -731.55588644734 425.331014023051 -1.71996835953207 0.086411106058026 GGA2 other 1 1 1 -1.66994620591131 -1.71996835953207 0.0747865172184078 64.7921283918023 39.4244325875379 1.64345113269387 0.101271753874923 -145.676019925962 127.921600913412 -1.13879140728208 0.255641965554941 CPPED1 other 1 1 1 1.64345113269387 -1.13879140728208 0.0235136268480524 69.7924001938726 54.4347359265639 1.28212985708293 0.200728074750807 -335.088767123288 167.041195038927 -2.00602472369285 0.0456975579979868 USP31 other 1 1 1 1.28212985708293 -2.00602472369285 4.23699022761761e-06 219.253445796655 84.1411148309629 2.60578251473288 0.009597655995247 -865.720465624933 247.571452987158 -3.49685093002157 0.000537765017336029 HMOX2 other 0.0417682496638544 1 1 2.60578251473288 -3.49685093002157 1.12615467286094e-05 152.172351208221 46.7894230044154 3.25228099508431 0.00126773555859675 -359.437918270136 137.670215814293 -2.61086187846899 0.00945927781484928 DNAJA3 essential 0.106950909281603 1 1 3.25228099508431 -2.61086187846899 0.000162532166198694 67.0946059692071 24.9753042674903 2.68643798091951 0.00760128968131737 -179.048939399254 73.485743310161 -2.43651259868928 0.015378031406319 CORO7-PAM16 other 1 1 1 2.68643798091951 -2.43651259868928 3.09018215028362e-06 149.866163372221 36.5324468973343 4.10227554133956 5.19500272232993e-05 -230.788254636182 115.569103994873 -1.99697191254871 0.0466748492349842 BFAR other 0.0308060258561774 1 0.553423640009808 4.10227554133956 -1.99697191254871 0.0155156428735679 14.2835011347789 5.7262095311798 2.49440769797259 0.0131305259731012 -2.1594821033059 15.1133584871263 -0.142885653453226 0.886472133822721 SALL1 other 1 1 1 2.49440769797259 -0.142885653453226 0.413253996748232 -7.03115831551747 5.62660258386073 -1.24962767686589 0.212363264335674 -2.68293072812565 14.8508915043065 -0.180657890292152 0.856752287813395 TOX3 other 1 1 1 -1.24962767686589 -0.180657890292152 0.0258858096402751 8.99521326085895 3.73409062614516 2.40894347819968 0.0165669868173303 -7.40338377160758 13.5242478420084 -0.547415564850232 0.584477244196247 RRN3P2 other 1 1 1 2.40894347819968 -0.547415564850232 8.05176165017607e-06 201.176286152519 57.7776523750003 3.48190481757208 0.000567511668358064 -229.74497070153 152.884164166727 -1.5027388346839 0.13389878818329 RBL2 ts 0.0774982058829446 1 1 3.48190481757208 -1.5027388346839 0.167620359732013 52.0595255496737 38.6993862655895 1.34522871221769 0.179503902349406 -109.992763531604 121.121517592601 -0.908119099874318 0.36449868639789 XYLT1 other 1 1 1 1.34522871221769 -0.908119099874318 0.0630977191945248 -53.2867770726353 102.07158889287 -0.522052979194465 0.602005067389301 -826.745571053752 350.897447293099 -2.35608887277879 0.0190887320213318 PYCARD other 1 1 1 -0.522052979194465 -2.35608887277879 0.000193963334435828 22.7037972323677 6.8688068328221 3.30534804442007 0.00105697075701935 -13.9478305216098 18.1753973775697 -0.767401682167506 0.443412127041517 RPGRIP1L other 1 1 1 3.30534804442007 -0.767401682167506 0.0037208212146726 509.586501177992 170.412379693521 2.99031386155431 0.00300518814480431 -419.083146628061 617.059930508846 -0.67916117366829 0.497531315654719 MAZ other 1 1 1 2.99031386155431 -0.67916117366829 7.6377966250633e-06 122.501799609804 42.1458478325435 2.90661609410578 0.00391604163510261 -435.994500257888 144.887236290254 -3.00919881848292 0.00283357486977335 STX4 other 0.0737123752284859 1 1 2.90661609410578 -3.00919881848292 1.27489615110517e-05 221.298033234562 54.878033173457 4.03254308577513 6.91792848971747e-05 -288.136099234212 198.712296591226 -1.45001645180993 0.148042585149704 CDIPT essential 0.120592426933038 1 0.729357200670913 4.03254308577513 -1.45001645180993 1.69127939905986e-12 220.925262933644 34.1141609069187 6.47605736328805 3.67188762445684e-10 -250.800831969143 117.276238262027 -2.13854772020216 0.0332511474671492 BCKDK other 2.21692903628767e-08 1 4.93464977850755e-06 6.47605736328805 -2.13854772020216 6.57891625342715e-05 84.3938342340727 24.8367917124932 3.39793622344635 0.000767324177639258 -153.361833695872 85.382885731419 -1.79616596911807 0.0734385706913039 KAT8 essential 0.578549895326383 1 1 3.39793622344635 -1.79616596911807 0.0197662643067773 211.520600305191 94.7007805222638 2.23356765528942 0.0262023352140424 -304.335575341855 296.367399982716 -1.02688613983726 0.305249670018539 NOMO1 other 1 1 1 2.23356765528942 -1.02688613983726 0.0129899798481436 -70.3220954498644 23.8514223927314 -2.94833969613882 0.00343068149591341 -100.180286468063 83.1137620108133 -1.20533933303404 0.228965679935176 IL21R other 1 1 1 -2.94833969613882 -1.20533933303404 0.664754516146373 -0.620847656204772 14.5682074360557 -0.0426166128488945 0.966033814270386 -39.3081192797127 44.7259883325628 -0.878865302817566 0.380135828471585 SYT17 other 1 1 1 -0.0426166128488945 -0.878865302817566 0.440361667248699 -45.8845289789227 48.4366235359645 -0.947310642841425 0.344197551587371 -162.938299196888 148.705725714517 -1.09570965350517 0.274032390898928 TMC5 other 1 1 1 -0.947310642841425 -1.09570965350517 0.311125166652851 -3.82921595087764 22.8428240373486 -0.167633211402267 0.866978062613973 -105.721638781374 70.1299652590513 -1.50751021180249 0.132669594404807 CCP110 other 1 1 1 -0.167633211402267 -1.50751021180249 2.14711709091186e-07 226.510212904348 42.180754636584 5.36998958069595 1.51976732728238e-07 -32.6335773609451 128.492619424737 -0.253972387729707 0.799680510348452 C16orf62 other 0.00232661607971209 1 0.0018793442769174 5.36998958069595 -0.253972387729707 4.99498264474719e-07 81.6812330035734 18.8218354404049 4.33970604313264 1.91919349528773e-05 -48.881173360761 49.6156786994928 -0.985196104175448 0.325276738224797 SLC6A2 other 0.00528069565202673 1 0.211168860286509 4.33970604313264 -0.985196104175448 2.95349636939752e-18 558.540404208561 66.9223448144873 8.34609734247758 2.29439914717645e-15 -500.959024217001 230.291468283366 -2.17532602467316 0.0303537963387798 RNF40 essential 4.22143236077988e-14 1 3.31517732775525e-11 8.34609734247758 -2.17532602467316 0.000536088315391863 70.7812486183181 23.5239046936164 3.00890730260125 0.00283073267481016 -112.710082522664 71.6594133799363 -1.57285801273698 0.116742958323666 KNOP1 other 1 1 1 3.00890730260125 -1.57285801273698 0.515207248090017 15.0978279181893 22.6247585661878 0.667314432285374 0.505053738399046 -28.4540450467283 44.7560475650983 -0.635758664912076 0.52538955685105 AQP9 other 1 1 1 0.667314432285374 -0.635758664912076 7.47589495042875e-08 180.230998376844 52.4934187229243 3.4334018008649 0.000674734405641071 -327.85879403831 101.551072437136 -3.22851139008176 0.00137383163762121 AAGAB other 0.000830123375295609 1 1 3.4334018008649 -3.22851139008176 0.386737636164503 1.12360551413761 3.7154535542767 0.302414092310286 0.762532883121544 -8.3176340696298 7.23776562118136 -1.14919914583697 0.251332087580565 IQCH other 1 1 1 0.302414092310286 -1.14919914583697 9.90279479090435e-09 70.8674720591784 17.9449257647881 3.94916496106304 9.64943518853248e-05 -108.045270384963 35.0533865417715 -3.08230619190561 0.00223262202111705 LACTB other 0.00011498135031719 1 1 3.94916496106304 -3.08230619190561 0.867566058606229 3.74305961514123 7.06476640123356 0.529820719123518 0.596603637499414 1.91985298105839 13.7496198176434 0.139629532054032 0.88904054487672 CORO2B other 1 1 1 0.529820719123518 0.139629532054032 2.1518724377701e-05 95.9903965009043 92.513720686382 1.03758011015802 0.300248969060432 -699.65070837691 181.768096057964 -3.84913922492645 0.00014312259497378 CSK other 0.199263387737511 1 1 1.03758011015802 -3.84913922492645 0.138647126534923 73.3393416177936 57.7123033831054 1.27077481435722 0.204734707398559 -111.169300560044 112.93739672122 -0.984344457969576 0.325692160747604 HERC1 other 1 1 1 1.27077481435722 -0.984344457969576 3.24102030611413e-06 47.8789338325846 19.8096583485228 2.41694899478944 0.0162101124927997 -130.724306465334 38.7641296046023 -3.37230083065798 0.00083688152282556 TRIP4 other 0.0322351879646112 1 1 2.41694899478944 -3.37230083065798 0.0001495696173591 23.2169536501879 9.22450059153657 2.51687919793613 0.0123283979997814 -41.7173893091888 18.0649299513163 -2.30930257806779 0.0215632870766179 MTFMT other 1 1 1 2.51687919793613 -2.30930257806779 0.928613957304815 -2.75394009849255 9.50668390721458 -0.289684618250807 0.772245131284511 -6.33085307962009 18.6175476004311 -0.340047637610094 0.734043751309443 RASL12 other 1 1 1 -0.289684618250807 -0.340047637610094 0.18398963473101 -37.4576233687032 30.0217420458221 -1.24768320610882 0.21307381782757 -100.915988190671 59.2170663294418 -1.70417067993957 0.0893353216239693 AP3B2 other 1 1 1 -1.24768320610882 -1.70417067993957 0.000195481403462355 123.142650305742 44.5788402680801 2.7623565253203 0.00607033071586035 -163.355594949151 86.4875013964595 -1.88877690199798 0.0598258769989413 ACSBG1 other 1 1 1 2.7623565253203 -1.88877690199798 0.0270201993332175 26.433164772768 10.2371028622627 2.58209428276913 0.0102644211494751 3.49299754165199 20.0479737928435 0.174231948711888 0.861793352206853 IGDCC4 other 1 1 1 2.58209428276913 0.174231948711888 7.30632910559649e-05 286.268679903632 155.621016270548 1.83952454985869 0.0667642644398573 -946.866976821469 304.996198413007 -3.10452058664443 0.00207614659762265 RAB11A other 0.639376860030749 1 1 1.83952454985869 -3.10452058664443 0.346768149859126 -61.1242464835899 181.017701316467 -0.337669996022812 0.735833284007898 -508.448768980515 352.533824978113 -1.44226945885854 0.150204382300361 CTSH other 1 1 1 -0.337669996022812 -1.44226945885854 2.55157267132029e-24 158.357512155142 14.494107162666 10.9256479462937 7.93627472451522e-24 -18.0643844858615 39.8619245761095 -0.453173916662519 0.650730639346066 TTC23 other 3.79163698958195e-20 1 1.19250464010566e-19 10.9256479462937 -0.453173916662519 4.97158973885362e-05 869.09835129803 223.043107213518 3.89654879792382 0.000118851138692128 -293.212170373656 438.643103977412 -0.668452707257779 0.504326542956393 CD276 other 0.44391324778224 1 1 3.89654879792382 -0.668452707257779 7.79464529712691e-06 131.660261892358 33.9805535256049 3.87457672792617 0.000129646474370365 -98.4079740607022 66.8794688240592 -1.47142278177456 0.142162594013702 FAH other 0.0751481753096006 1 1 3.87457672792617 -1.47142278177456 0.983443907584519 11.902666276202 151.19014403769 0.0787264695854433 0.937299551242771 54.2083714764084 297.567740238678 0.182171533221068 0.855563821415474 CEMIP other 1 1 1 0.0787264695854433 0.182171533221068 6.94401627896287e-09 128.30067037044 30.3889989688298 4.22194460903563 3.16503409851793e-05 -155.689440603551 60.680922452498 -2.56570655670944 0.0107546047358543 RPAP1 essential 8.11963823499128e-05 1 0.342931444574417 4.22194460903563 -2.56570655670944 0.0117619164850403 188.982923181476 65.5941828030764 2.88109272965304 0.00423490317675201 25.0699420397651 129.382734284596 0.193765746089583 0.846484197957523 HOMER2 other 1 1 1 2.88109272965304 0.193765746089583 8.47762706394202e-10 448.389092756495 102.668122944538 4.36736427916108 1.70060159829416e-05 -594.760542800999 205.131749267768 -2.89940755111794 0.00399714649081879 EHD4 other 1.02842093912681e-05 1 0.187848452547573 4.36736427916108 -2.89940755111794 5.33096343680376e-07 189.968303099166 78.7896129573326 2.41108308530517 0.0164683293560367 -561.954620762224 157.55545795032 -3.56670995770529 0.000416729817435923 TMEM87A other 0.00562576571485901 1 1 2.41108308530517 -3.56670995770529 0.0274058005027019 562.074433436048 278.789342643517 2.01612596846919 0.0446247313417383 -487.989818008571 564.071932052695 -0.865119837168185 0.387623130952897 ZNF106 other 1 1 1 2.01612596846919 -0.865119837168185 0.0496735307858226 -7.28503275701993 12.746244180307 -0.571543480100229 0.568036308696961 -63.2976336218264 25.926457802201 -2.44143006749086 0.0151758071277088 CEP152 other 1 1 1 -0.571543480100229 -2.44143006749086 0.251629019415882 -10.6250560253752 6.42667576435427 -1.65327401209617 0.0992619373224169 -10.5814841265541 13.7286582465584 -0.770758797875005 0.441422180388369 ATP8B4 other 1 1 1 -1.65327401209617 -0.770758797875005 0.263503373674725 -25.0662774146006 15.5968265403818 -1.60713959020455 0.109019302946633 -11.9796793109469 33.8097563033125 -0.354326106449137 0.723330083502958 OCA2 other 1 1 1 -1.60713959020455 -0.354326106449137 0.0606454064272711 15.6034366612048 10.6509605304645 1.46497929614657 0.143917634043165 -26.5741859065225 21.6803589848123 -1.22572628641152 0.2212115250398 DTWD1 other 1 1 1 1.46497929614657 -1.22572628641152 0.268982255457802 6.74078413209684 24.1567752083934 0.279043211436381 0.780391914116586 -66.7152327561985 48.9100999305885 -1.36403795639098 0.173514245207527 TGM5 other 1 1 1 0.279043211436381 -1.36403795639098 0.198284566032663 -0.923020092053204 3.50198446618934 -0.263570584325744 0.792282615004489 -13.1438335013719 7.52877861056805 -1.74581219361691 0.0818154484619221 FAM189A1 other 1 1 1 -0.263570584325744 -1.74581219361691 3.27054929291235e-05 413.474710847668 128.317465849499 3.22227927515826 0.00140437662964814 -494.728765001876 275.864670896507 -1.79337485802043 0.0738691119175783 TJP1 other 0.297489163683307 1 1 3.22227927515826 -1.79337485802043 0.0127464335285442 -48.2471753257792 31.3699010730641 -1.53800852649825 0.125034714773823 -184.953224504552 62.7426747819277 -2.94780586175815 0.00343570012813095 BMF other 1 1 1 -1.53800852649825 -2.94780586175815 0.021649557044244 19.933850679613 22.764563283503 0.875652672593051 0.381883988208966 -104.301783816058 47.6926521219537 -2.18695709245421 0.02947845655792 DMXL2 other 1 1 1 0.875652672593051 -2.18695709245421 0.00830492775620666 -48.5281757110418 41.5218774364228 -1.1687375115768 0.243382041374812 -258.393838522938 82.9002959902 -3.11692299088394 0.0019937778487134 DNAJC17 essential 1 1 1 -1.1687375115768 -3.11692299088394 8.86736612539775e-12 345.423518419648 60.7937178397145 5.68189495056667 3.00388881276785e-08 -271.651937728286 121.911148497863 -2.22827806214168 0.0265587186837241 EIF3J other 1.14211675695123e-07 1 0.000381734190326538 5.68189495056667 -2.22827806214168 0.000128897766452702 84.2159225980509 54.7141733962379 1.53919756747785 0.124753634925258 -342.996136403428 110.458115048242 -3.10521446299917 0.00207307345223477 SPG11 other 1 1 1 1.53919756747785 -3.10521446299917 0.0109276580626549 105.545913145872 175.553225959969 0.601218875749626 0.548121190622378 -863.992547081436 350.499912158348 -2.46502928277798 0.0142265612092969 RHOV other 1 1 1 0.601218875749626 -2.46502928277798 0.000381889455975164 59.4664544092885 38.7212159043104 1.5357589636711 0.125588721587916 -213.782528750979 77.308649265266 -2.76531191248001 0.00601794198791655 VPS18 essential 1 1 1 1.5357589636711 -2.76531191248001 0.0365952940666002 -2.50168496753279 13.2277180154104 -0.189124455527273 0.850115544640566 -64.2361681743188 26.4097340114613 -2.43229137205402 0.015553299162402 OIP5 essential 1 1 1 -0.189124455527273 -2.43229137205402 0.000312516426976518 45.6373879500153 13.7416797049716 3.3210923940764 0.00100067021082345 -26.7363187186651 28.0243797234238 -0.954037840713309 0.340786853226303 SLC30A4 other 1 1 1 3.3210923940764 -0.954037840713309 0.009684839416505 88.408097227144 40.8362204657079 2.16494318570408 0.0311332151829587 -101.36342682693 83.280193787839 -1.21713725937237 0.224451652398306 BLOC1S6 other 1 1 1 2.16494318570408 -1.21713725937237 0.162258187282185 -26.0324751200613 14.6744072786954 -1.77400522049403 0.0770191290928286 -39.4125886505774 30.0185053977214 -1.31294307056237 0.19014880060015 MYEF2 other 1 1 1 -1.77400522049403 -1.31294307056237 0.203627723534617 17.0933123490742 13.0892350895625 1.3059061306573 0.192531334806528 -62.3301444560725 60.9567021872563 -1.02253143985049 0.307309129129486 SGK3 other 1 1 1 1.3059061306573 -1.02253143985049 0.000341684294410892 57.8998165939183 27.2931049707618 2.12140819653699 0.034655857907819 -67.9659043442888 50.7516338967495 -1.33918652712857 0.181460393745728 PDGFRL other 1 1 1 2.12140819653699 -1.33918652712857 6.52030604983761e-08 45.1319461614901 7.96425239674836 5.66681515265846 3.2617959545225e-08 -30.7992185683489 37.1901259167728 -0.828155802356625 0.408203364384036 CSPP1 other 0.000726231687830913 1 0.000413726198871634 5.66681515265846 -0.828155802356625 5.09744992940126e-05 46.0462582788106 50.4540668089953 0.91263720034955 0.362120431157207 -268.311366252186 93.819531710862 -2.85986682473626 0.00451662900500066 ZDHHC2 other 0.454539610204711 1 1 0.91263720034955 -2.85986682473626 4.27650403006716e-14 99.2690866908571 17.2878581942174 5.74212754267396 2.34361372464587e-08 -80.4907744470037 39.7147160629048 -2.02672415735046 0.0435991770629082 BRF2 essential 5.78055049744177e-10 1 0.000299091983539306 5.74212754267396 -2.02672415735046 1.47733207615966e-15 127.317877145908 37.0105035166894 3.44004715008797 0.000658713394399864 -280.943365156563 68.0351090310351 -4.12938803446919 4.64630600810784e-05 TRIM35 other 2.0486163900106e-11 0.670973050630853 1 3.44004715008797 -4.12938803446919 2.12406133436764e-05 79.2245952803502 17.1993381528096 4.60625836741332 5.93928275582018e-06 -48.3522065988483 83.187244870676 -0.581245438216127 0.561486791687844 ZFAND1 other 0.196836763855849 1 0.0676840662853268 4.60625836741332 -0.581245438216127 0.000215592332702062 626.544663390603 161.103882060987 3.88907241324837 0.000122473491735511 -849.556662073674 792.790904185516 -1.07160243336353 0.284708691134724 CA2 other 1 1 1 3.88907241324837 -1.07160243336353 0.000381712940266877 41.128237502368 21.0815804514858 1.95090864259512 0.0519404237808573 -59.6436761894918 38.6741778126715 -1.54220928699226 0.124011031111534 FZD3 other 1 1 1 1.95090864259512 -1.54220928699226 7.36493052541308e-47 112.769424325395 15.4563761977011 7.29598082260493 2.35325576668854e-12 -221.935650496806 28.3547356795683 -7.82711054001207 7.36522725640647e-14 INTS9 essential 1.127644512746e-42 1.12989951340532e-09 3.28796895721723e-08 7.29598082260493 -7.82711054001207 7.26130751777485e-07 77.0158811236881 15.3631228089187 5.013035571061 8.88848158538931e-07 -125.92796245229 77.7351965779141 -1.6199606869981 0.106225736444061 RIPK2 other 0.0075887924868265 1 0.0106208466463817 5.013035571061 -1.6199606869981 0.456000534570991 -7.78245379795801 7.23897034632131 -1.07507745240494 0.283155069010785 -26.4648651013737 33.9136869192155 -0.780359421386845 0.435759811871154 EYA1 other 1 1 1 -1.07507745240494 -0.780359421386845 4.00284493840206e-06 162.20315200396 33.9963241358077 4.77119677280385 2.7883765575264e-06 -223.002409462801 172.016521152154 -1.29640111292304 0.195771450034725 NBN ts 0.0395320966116587 1 0.0324260309874745 4.77119677280385 -1.29640111292304 0.0991007742267725 16.3447787700795 7.71105572217115 2.1196551236278 0.0348120028649375 -4.65793428972786 35.6687558535741 -0.130588639223903 0.896183561341391 TRPA1 other 1 1 1 2.1196551236278 -0.130588639223903 0.0544018452025223 38.0662869309413 15.8264685902411 2.40522936079459 0.0167296217611888 -8.31275361004724 82.0582983494155 -0.101303022086205 0.919373360694124 CPQ other 1 1 1 2.40522936079459 -0.101303022086205 0.0222702638772283 76.9668767100478 40.4759630841371 1.90154528380356 0.0581286062288897 -375.168619734476 204.802564306732 -1.83185508933662 0.0679023786218086 DECR1 other 1 1 1 1.90154528380356 -1.83185508933662 0.0762932976567911 78.689009111003 141.29964532954 0.556894597488081 0.577988716640513 1609.63907027077 714.955926779736 2.25138223207801 0.0250394490701632 CALB1 other 1 1 1 0.556894597488081 2.25138223207801 9.68938655653485e-10 389.551637331844 59.4374798553471 6.55397298606696 2.33553827728956e-10 -60.1407779164798 274.484803287714 -0.219104217050007 0.826713053009949 IMPAD1 other 1.17183441014732e-05 1 3.14994047458043e-06 6.55397298606696 -0.219104217050007 0.0554287655646894 368.448366808133 221.950144276103 1.66005013427605 0.0980318800933262 -333.774329615433 538.397588998273 -0.61994023828458 0.535804936025389 SFRP1 other 1 1 1 1.66005013427605 -0.61994023828458 4.2619111239711e-08 726.545439585758 125.398166855586 5.79390797971137 1.64980603164944e-08 1314.73182697986 672.165711003242 1.95596384263273 0.0513419065177627 LAPTM4B other 0.00047937976322427 1 0.000211802098343156 5.79390797971137 1.95596384263273 1.57139626799699e-07 108.188292825249 19.4147775078692 5.57247142190518 5.37177178740483e-08 -66.8166793216676 89.8062449333029 -0.744009276540745 0.457421987863918 UBE2W other 0.00171565044539911 1 0.000675930044009149 5.57247142190518 -0.744009276540745 1.98542266767482e-05 50.8416729845842 10.7420334014576 4.73296545304777 3.3352290227985e-06 24.6314126863786 58.6944500198338 0.419654885224331 0.675020956693997 POP1 essential 0.184306786240253 1 0.0386119463969383 4.73296545304777 0.419654885224331 0.000235464936196162 118.772428607531 34.2713103530484 3.46565180566451 0.000601602951288657 469.331900939047 187.258374411521 2.50633330773042 0.0126979614937406 NIPAL2 other 1 1 1 3.46565180566451 2.50633330773042 4.21024148436287e-28 90.309861965403 28.500224824564 3.16874208962611 0.00170573804080858 -584.040374610977 66.7318556670701 -8.75204756068519 2.25413599598237e-16 IKBKB other 6.33641343396612e-24 3.46167664903013e-12 1 3.16874208962611 -8.75204756068519 1.23276581185338e-05 -370.913769302853 262.185465885877 -1.41469996458272 0.15830021911271 -2881.02881656945 613.894198210682 -4.69303802669384 4.26999788298181e-06 PLAT other 0.116712483056802 0.0633881185728649 1 -1.41469996458272 -4.69303802669384 0.53276763833742 22.4248498770678 22.0017793219981 1.01922892457369 0.308869081847215 59.3650822801 101.679719144945 0.583843885283305 0.55973924254128 JPH1 other 1 1 1 1.01922892457369 0.583843885283305 6.10330614775777e-11 134.464997077329 18.8892711145461 7.118591091309 7.29230113720069e-12 30.0133704376465 105.166163849379 0.28538998988907 0.775531168441337 STK3 other 7.69321739924867e-07 1 1.01085878363876e-07 7.118591091309 0.28538998988907 0.00013194699013071 62.3180532225968 14.5544967578133 4.28170442850541 2.45882238074074e-05 18.2591249253941 67.2626118538886 0.271460242505264 0.786213212882024 GDAP1 other 1 1 0.268503403976888 4.28170442850541 0.271460242505264 2.51755369755293e-26 536.098266640893 47.1207253497762 11.377122543455 2.54650952944991e-25 -434.52594055213 219.385842993069 -1.98064713120918 0.0485088487550711 RAB2A other 3.769533151346e-22 1 3.83886311564574e-21 11.377122543455 -1.98064713120918 1.44515501323355e-12 801.500114081888 103.996679504017 7.7069779333765 1.63524496895039e-13 79.6048927013309 570.168644780922 0.139616398463858 0.889050913902106 EIF3E other 1.89763304787698e-08 1 2.31959498845613e-09 7.7069779333765 0.139616398463858 9.79171581741367e-14 122.806588851178 15.3935341521876 7.97780338400884 2.67779771527007e-14 -94.6386663775058 84.3960648339988 -1.12136349678926 0.26297394667896 EMC2 other 1.31659410880944e-09 1 3.83326742940911e-10 7.97780338400884 -1.12136349678926 3.31051251574778e-07 415.007604053179 76.7919776095815 5.40430936891769 1.27333384317783e-07 -360.076919628933 389.095854150574 -0.92541957409186 0.355445056478611 ESRP1 other 0.0035492004681332 1 0.00157855196538755 5.40430936891769 -0.92541957409186 0.569079050217897 39.5151318952836 37.5758648349551 1.05160937928765 0.29377475555235 55.1829000696648 212.775163625399 0.259348408570922 0.795533717692665 WISP1 other 1 1 1 1.05160937928765 0.259348408570922 4.91894865731102e-08 13762.0826505691 2319.63053163556 5.93287700902332 7.74854228679373e-09 792.350838637552 13135.0207929238 0.0603235313540132 0.951935734689814 NDRG1 other 0.000551364954997993 1 0.000100483096375141 5.93287700902332 0.0603235313540132 0.556217447038232 -3.31161899981032 11.0296647238037 -0.300246569840272 0.764185884941673 -56.4224547393188 52.9721785496642 -1.06513374160022 0.287626021125645 ZC2HC1A other 1 1 1 -0.300246569840272 -1.06513374160022 0.209601017834578 -4.99351434412489 3.77408474471214 -1.32310604607416 0.186753676290724 -23.5060009081834 18.1257994657801 -1.29682560775102 0.195634328695941 IL7 other 1 1 1 -1.32310604607416 -1.29682560775102 1.22819752033382e-11 157.705639007263 22.7336140271606 6.93711254263606 2.28079017772433e-11 -167.014574868216 107.206559461482 -1.55787645557473 0.120266632995193 ARMC1 other 1.57590023834032e-07 1 3.13471802026432e-07 6.93711254263606 -1.55787645557473 0.111123492802683 67.490822394334 32.1842686773837 2.09701276952615 0.0367819136243359 49.9969428049764 176.290391520478 0.283605603083414 0.776897194172461 TRPS1 other 1 1 1 2.09701276952615 0.283605603083414 0.00138147307943484 40.6413687928039 11.5040885549443 3.53277607336714 0.000471730736132499 -60.2705641695991 69.6821339888103 -0.864935683216555 0.387722021159813 SPAG1 other 1 1 1 3.53277607336714 -0.864935683216555 3.60124176989862e-12 162.070494158134 21.414188843444 7.56836952092872 4.09044724889427e-13 63.9277445578522 109.663014857477 0.582947173583871 0.560340719373781 CHRAC1 other 4.68449529428412e-08 1 5.76630348676625e-09 7.56836952092872 0.582947173583871 0.653934128564522 29.0911104214861 32.6000554750307 0.892363831827461 0.372870591113997 -41.3909185803757 188.817840269727 -0.219210846396976 0.826625998761815 NCALD other 1 1 1 0.892363831827461 -0.219210846396976 1.32658978222942e-05 47.7257556571311 10.1472284401319 4.70332918379736 3.82143635018206e-06 -30.5257288248892 49.0786313698967 -0.62197595924838 0.534403346928556 SNX16 other 0.125283139033747 1 0.0440688039902996 4.70332918379736 -0.62197595924838 2.02892353135074e-16 635.260469350849 70.5438304109193 9.00518820214955 2.02449761924786e-17 56.9820906495123 403.049572553881 0.141377375215786 0.887661345385807 UBR5 other 2.84272475977553e-12 1 2.96325716529309e-13 9.00518820214955 0.141377375215786 0.0236022214868218 155.068682818297 69.489193451939 2.23155105297844 0.0263368828811722 -455.783573289233 336.433207554058 -1.35475203712165 0.17645225040379 GSDMD other 1 1 1 2.23155105297844 -1.35475203712165 8.68176255966181e-06 430.652796948329 88.5190899297719 4.86508387388522 1.80088196947643e-06 -61.1474520995206 435.358626000897 -0.140453062022009 0.888390679526537 TSTA3 other 0.0833101935225147 1 0.0211549604954396 4.86508387388522 -0.140453062022009 5.4470102757934e-11 132.57996001372 18.5770502828847 7.13676057257958 6.47269293903132e-12 65.4210993956639 91.3664961165183 0.716029421903554 0.474496997655174 PYCR3 other 6.87630577216159e-07 1 8.97956691431815e-08 7.13676057257958 0.716029421903554 6.09036449232279e-05 1653.22284404514 408.065722963178 4.05136415781318 6.40059776439337e-05 -2829.46506100119 2006.96745310257 -1.40982109930438 0.159566719746443 EEF1D other 0.538144606541641 1 0.676735201629311 4.05136415781318 -1.40982109930438 0.0309102763686235 3.37722406513872 1.32165100404413 2.55530700223035 0.0110730312666319 6.42710573241727 7.63000082131901 0.842346663247961 0.400225021080455 ANXA13 other 1 1 1 2.55530700223035 0.842346663247961 1.77292256967303e-06 560.104322741756 106.891751065442 5.23992092148293 2.94189635106428e-07 -38.174391377827 627.998652883121 -0.0607873778113529 0.95156696946125 SQLE other 0.0179756619339148 1 0.00359352639282502 5.23992092148293 -0.0607873778113529 2.08618289952195e-17 7.44626540045679 41.4683095499265 0.179565202470859 0.857608286624435 -550.474768044769 77.0575154361965 -7.1436869580951 6.23153128257495e-12 SH2D4A other 2.9557039320427e-13 9.54608277177657e-08 1 0.179565202470859 -7.1436869580951 1.96424242984927e-26 200.569152209491 49.0794112178326 4.08662506808183 5.54720496530543e-05 -562.488314238952 90.7079841979996 -6.2010893441435 1.74096315901104e-09 INTS10 essential 2.94223873567122e-22 2.65514291380773e-05 0.588946751166477 4.08662506808183 -6.2010893441435 8.20660233876378e-33 64.490219148179 16.3513519848284 3.94402977857833 9.85485239103886e-05 -238.578350826831 31.6747264587561 -7.53213610660491 5.17928180716233e-13 ERI1 other 1.24485950876708e-28 7.94087486674129e-09 1 3.94402977857833 -7.53213610660491 0.00104816298453833 458.858736523597 151.455680314474 3.02965683142982 0.00264779752688869 55.7448008565195 280.072748075663 0.199036861813702 0.84236031326554 SLC39A14 other 1 1 1 3.02965683142982 0.199036861813702 4.24818221470286e-23 44.1266878092787 13.2271987629471 3.33605690820109 0.000950057358047084 -150.908369978428 25.503205287723 -5.91723151172194 8.44235757471916e-09 MTMR9 other 6.283486313767e-19 0.000128366046923605 1 3.33605690820109 -5.91723151172194 5.23176235966832e-36 150.173919289632 24.1790922485802 6.21089980325667 1.64128718845986e-09 -308.601849164541 46.3250944863094 -6.66165611935759 1.18724946158392e-10 LEPROTL1 other 7.96692772130291e-32 1.81554187665413e-06 2.17125882161354e-05 6.21089980325667 -6.66165611935759 3.30549401856129e-37 102.317954813179 16.069674569561 6.3671454185506 6.70498874622676e-10 -209.751955673747 30.735428130344 -6.82443578739891 4.45206236208027e-11 DCTN6 essential 5.03856453249297e-33 6.81388144516385e-07 8.96456995370518e-06 6.3671454185506 -6.82443578739891 5.15891812940394e-20 153.426909316397 29.9569335403669 5.12158259154446 5.24435975961675e-07 -196.789074773131 55.3965403156208 -3.55237120679251 0.000439192741261857 R3HCC1 other 7.48610609757806e-16 1 0.00633256440973723 5.12158259154446 -3.55237120679251 1.09686566501112e-09 424.154629723891 202.812663890158 2.09136166148684 0.0372863443908228 -1537.5345839802 406.220362166588 -3.7849766461231 0.000183608392380328 GSR other 1.32314905170291e-05 1 1 2.09136166148684 -3.7849766461231 1.07786311350158e-15 84.5433620237233 28.6018303431695 2.95587243925853 0.00335020421290823 -241.362664767895 52.8731505201084 -4.564938203864 7.14196032801059e-06 TNFRSF10A other 1.49701039686862e-11 0.105529605806684 1 2.95587243925853 -4.564938203864 4.84530028922478e-12 21.7765345102162 8.42682189487642 2.584193042392 0.0102048625089884 -69.3695939545971 16.9795497678001 -4.08547899698431 5.56928029632488e-05 UBXN8 other 6.28483900515346e-08 0.802032055473745 1 2.584193042392 -4.08547899698431 1.55038306928035e-43 382.655475523821 47.3255878890951 8.08559370504922 1.29969975246417e-14 -632.334103828787 95.3582720600589 -6.63114054154136 1.42423417828254e-10 PPP2CB other 2.37162098107815e-39 2.17751163517618e-06 1.86610890458806e-10 8.08559370504922 -6.63114054154136 2.89644933110471e-36 86.8461959665734 11.1963976350717 7.75661947683381 1.37288321089128e-13 -103.217077594141 21.4102297703466 -4.82092339509115 2.27456249623617e-06 ERICH1 other 4.41158197620558e-32 0.0339137268188813 1.94894500618126e-09 7.75661947683381 -4.82092339509115 0.666169531007799 -79.3428903676662 109.5097622496 -0.724528012277336 0.469272695094096 -176.315076115019 202.067161483607 -0.872556801513358 0.383560985728776 NEFM other 1 1 1 -0.724528012277336 -0.872556801513358 1.72859501367565e-10 203.012815956907 93.0706842745026 2.1812756351736 0.0298951887760301 -648.480115644266 173.604440251479 -3.73538899526357 0.000222089809047929 TUSC3 other 2.14708786648652e-06 1 1 2.1812756351736 -3.73538899526357 4.39253925942754e-05 101.667495245751 36.2834950753726 2.80203147559392 0.00540739086369462 -69.7080529562191 69.4013960145442 -1.00441859903813 0.31598364953583 ARHGEF10 other 0.394493950889188 1 1 2.80203147559392 -1.00441859903813 0.000548505225146953 488.494715452639 160.663537824645 3.04048275088903 0.00258156805599978 -1499.55516144355 809.668125409197 -1.85206149826596 0.0650510009515081 MCM4 essential 1 1 1 3.04048275088903 -1.85206149826596 5.45346562248582e-27 145.615747625736 31.25392423697 4.65911885245721 4.6648320873508e-06 -336.1889275095 57.4660282350998 -5.85022034468981 1.2133653785999e-08 KCTD9 other 8.18347051310223e-23 0.000184334468316897 0.053496294377739 4.65911885245721 -5.85022034468981 7.8061221738015e-12 -39.1793736103173 106.740289909637 -0.367053280850983 0.713821883312892 -1192.57243947417 198.483980526588 -6.0084065036897 5.0946892965549e-09 ASAH1 other 1.00667751553344e-07 7.75513604721587e-05 1 -0.367053280850983 -6.0084065036897 4.57406802875127e-18 495.979446963506 107.356207670468 4.61994194584375 5.57128843303374e-06 -721.074142900795 197.016627233342 -3.65996592788471 0.000294956847777812 BNIP3L other 6.52445063621081e-14 1 0.0636018287515132 4.61994194584375 -3.65996592788471 0.233273018950711 112.671402462153 129.407754501703 0.870669635648998 0.384606116911988 -328.637290941067 281.178572778756 -1.16878497423648 0.243385369956268 MAN2B1 other 1 1 1 0.870669635648998 -1.16878497423648 0.000971607185815882 138.576551817862 40.0676642653105 3.45856326688444 0.000617063188433532 -150.243959968945 167.894050482903 -0.894873639279104 0.371531460558249 KCNN4 other 1 1 1 3.45856326688444 -0.894873639279104 3.99989467529656e-07 901.818222656247 224.478860459695 4.01738596146415 7.34009908704011e-05 -1461.31819940477 514.310403733024 -2.84131565062279 0.00478092491800485 NUCB1 other 0.00425708790291813 1 0.771884819993138 4.01738596146415 -2.84131565062279 0.75005695830524 0.71423828125 4.63996164288072 0.153931936559408 0.877760433566664 -7.33242559523812 10.6307584641548 -0.689736825454351 0.49085957949927 DHDH other 1 1 1 0.153931936559408 -0.689736825454351 3.96934811792765e-07 377.519511718749 87.5112019172844 4.31395642440817 2.13932140300256e-05 -491.045669642858 200.499599370169 -2.449110477953 0.0148569216979592 GYS1 other 0.00422576800634578 1 0.234597985053261 4.31395642440817 -2.449110477953 0.0249031738109121 -16.7178989299048 17.4633047188219 -0.957315880303361 0.339130527070024 -139.183973390186 51.1234184463787 -2.72250912830037 0.00683395964664384 MAP4K1 other 1 1 1 -0.957315880303361 -2.72250912830037 0.911239569174569 0.715605468749997 2.8627761108248 0.249969065357271 0.802771667133197 -1.87959821428572 6.55899417139068 -0.286568056804233 0.774628523118699 CGB2 other 1 1 1 0.249969065357271 -0.286568056804233 7.46512394094123e-11 711.457022286001 127.113547655628 5.59701963643922 4.69158024287852e-08 -978.052164581153 369.772702614368 -2.64500910333869 0.00857194208138132 ECH1 other 9.37694218221628e-07 1 0.000591889763441554 5.59701963643922 -2.64500910333869 0.00959900525742685 357.206430033835 138.313353273791 2.58258817083803 0.0102500467791743 -357.954882137179 402.352883630192 -0.889654074074389 0.374319980836594 HNRNPL essential 1 1 1 2.58258817083803 -0.889654074074389 7.05167434436849e-07 108.585070204206 26.6776161713406 4.07026885411365 5.92219763315286e-05 -204.002914410448 83.683226701541 -2.43779933508098 0.0153209869681129 NFKBIB other 0.00737393586190613 1 0.627279173303551 4.07026885411365 -2.43779933508098 0.683789218390751 2.226484375 2.55509843461584 0.871388884606611 0.384195128270239 1.38279761904763 5.85406440853188 0.236211548515301 0.813419637201349 CGB3 other 1 1 1 0.871388884606611 0.236211548515301 0.0111481614899047 44.997374308764 16.4704424624322 2.73200761979526 0.00664444924826961 1.68513830909814 29.6733576824284 0.0567896065936626 0.954748235973786 TUBB4A other 1 1 1 2.73200761979526 0.0567896065936626 4.0711733331193e-10 92.4008850000788 16.7255929563503 5.52452072947263 6.85209111009486e-08 -126.393010423861 52.4653918886347 -2.40907397951298 0.0165576009235915 SARS2 other 4.99777238373726e-06 1 0.000858772578828189 5.52452072947263 -2.40907397951298 0.247628209244502 13.81642578125 9.83904576966744 1.40424448718841 0.161215873275286 -12.9602827380953 22.5425396038749 -0.574925583622686 0.565745613756507 KCNA7 other 1 1 1 1.40424448718841 -0.574925583622686 0.345445134230426 136.029667968749 164.594763429429 0.826451978996723 0.409163530886546 -372.868883928573 377.108111910301 -0.988758587132337 0.323528301760051 SNRNP70 essential 1 1 1 0.826451978996723 -0.988758587132337 8.61729248677188e-52 1138.80561869691 62.853183871154 18.1185032890523 6.04248929583387e-51 -430.360425417755 259.533311766159 -1.65820881523491 0.0982582669408991 CLPTM1 other 1.32120328407186e-47 1 9.26555308623165e-47 18.1185032890523 -1.65820881523491 0.0437020509649156 64.9445836272888 62.1081775920643 1.04566880152006 0.296508151818033 -539.723818353571 256.453586808855 -2.10456724380248 0.0361134732812693 RELB other 1 1 1 1.04566880152006 -2.10456724380248 0.00785238222319467 80.8088733348384 28.1027685333477 2.87547731245581 0.00430633697151192 -39.2841499209755 68.5206303127326 -0.573318571964094 0.566834214921186 CLASRP essential 1 1 1 2.87547731245581 -0.573318571964094 0.0370248362905093 18.1267187499999 7.47091084276348 2.42630639442819 0.0158055968935813 -5.38583333333334 17.1168330235043 -0.314651274913863 0.753231501345745 LIN7B other 1 1 1 2.42630639442819 -0.314651274913863 7.12908708007297e-05 105.419197470231 39.2779193746255 2.68393028828137 0.0076560335665228 -266.092014503815 95.201952687357 -2.79502685598961 0.00550379725628156 PPP1R37 other 0.624721900826794 1 1 2.68393028828137 -2.79502685598961 0.0129742541709182 164.882655792365 90.4305593986916 1.82330682115354 0.0691926730777148 -402.666734546009 211.595118309103 -1.9030057865408 0.0579398674229256 FCGRT other 1 1 1 1.82330682115354 -1.9030057865408 9.38048145066411e-05 88.0387218397371 66.9054034677798 1.31586863357209 0.189162975878658 -594.027088959666 156.549476818651 -3.79450063348212 0.000176996155385983 PIH1D1 other 0.810661206966392 1 1 1.31586863357209 -3.79450063348212 0.349524194282712 3239.31783359279 2599.36862319455 1.24619409678484 0.213604680359129 -2657.96567441727 6235.80876398383 -0.426242332793925 0.670217848266435 CKM other 1 1 1 1.24619409678484 -0.426242332793925 5.69306357441374e-08 175.556770571882 59.3521926851084 2.95788180064878 0.00332829399986649 -353.06701988944 106.800695466717 -3.30584944551667 0.00105444621116976 ARHGEF18 other 0.000636085993169247 1 1 2.95788180064878 -3.30584944551667 0.00131581274611294 462.935167735982 149.848895262319 3.08934655090775 0.00218189291945319 -432.691486557251 359.48308601251 -1.20364908223302 0.229614883812146 PPP1R13L other 1 1 1 3.08934655090775 -1.20364908223302 0.0248667379816362 6.65759697306183 7.53671483484282 0.883355297228873 0.377707481964584 -26.1956502471425 13.561864347052 -1.93156704541413 0.0542957524749283 PEX11G other 1 1 1 0.883355297228873 -1.93156704541413 3.44603938016345e-06 288.224277632708 62.3368694047155 4.62365659977954 5.47855036349611e-06 -152.594325440224 149.544313601629 -1.02039537154666 0.308311796320699 ERCC2 ts 0.0342122789662628 1 0.0625869593525795 4.62365659977954 -1.02039537154666 6.40889839792739e-12 177.830616711129 58.719083226447 3.02849783988171 0.00265897127666946 -457.659388712072 101.962437206169 -4.48850970271221 1.0040343604067e-05 DOT1L other 8.28606473868033e-08 0.147823978882679 1 3.02849783988171 -4.48850970271221 0.3832416047506 0.481125677595148 12.0998257600023 0.0397630252813704 0.968306928163359 -38.1270877536082 28.3119343751871 -1.34667900993099 0.179039626715649 SLC17A7 other 1 1 1 0.0397630252813704 -1.34667900993099 0.000201507581282732 132.641139171971 48.030168802017 2.76162134092689 0.00608903271874071 -400.799536374173 158.925699837623 -2.52193029059288 0.0121640122680675 RNASEH2A other 1 1 1 2.76162134092689 -2.52193029059288 0.00159390751168774 260.260025506841 81.8813566327549 3.17850162979261 0.00162502216670851 -183.439068572792 196.430962788922 -0.933860252825364 0.351080098881316 KLC3 other 1 1 1 3.17850162979261 -0.933860252825364 0.103454299794299 -15.4589732919724 44.9064828335456 -0.344248142284357 0.730885790010728 -223.016812762784 104.537445492378 -2.13336772973895 0.0336549396775825 CD37 other 1 1 1 -0.344248142284357 -2.13336772973895 1.28276599159283e-15 319.687224389067 88.2961162554229 3.6206261152447 0.000341867293002612 -794.184703148196 153.321317611908 -5.17987136764937 3.94952831525457e-07 SF3A2 essential 1.77970953673589e-11 0.00594483002012118 1 3.6206261152447 -5.17987136764937 0.189214689243499 -3.16962395565519 3.59350172872705 -0.882043253330502 0.378423858824748 -20.7755476588869 11.919527084651 -1.7429842233959 0.0823090641159673 LYL1 other 1 1 1 -0.882043253330502 -1.7429842233959 5.81296444800171e-09 1062.05830989325 582.031315436263 1.82474427359149 0.0689836744471941 -4422.26836242062 1003.04735870533 -4.40883306659477 1.42621582126864e-05 OAZ1 other 6.82558285484361e-05 0.209183074505472 1 1.82474427359149 -4.40883306659477 9.21100010177199e-10 147.841455324756 27.2731607372575 5.42076720586299 1.18002322454201e-07 -249.614372306792 90.472179363117 -2.75901801044215 0.00613549070307878 TRMT1 other 1.11517578232153e-05 1 0.00146488083094646 5.42076720586299 -2.75901801044215 2.10782108683025e-16 225.461635885078 27.2968105070099 8.25963296434134 4.05154571136034e-15 -173.704173367075 90.5506318106184 -1.91830989904485 0.0559726107395257 STX10 other 2.95263577843182e-12 1 5.84435468863729e-11 8.25963296434134 -1.91830989904485 0.121801863600471 -8.31734574770376 5.98485942327268 -1.38973117987717 0.165576595265097 -21.9497469823347 11.1122732115412 -1.97527063675304 0.0490964974308967 FCER2 other 1 1 1 -1.38973117987717 -1.97527063675304 0.0207481849837694 125.037273475378 80.68267484992 1.54974130081785 0.122192019302823 -366.77017836977 193.555360498453 -1.8949109827041 0.05900540275379 DMPK other 1 1 1 1.54974130081785 -1.8949109827041 0.0582374575239518 -5.97971082089547 39.7325582964258 -0.150499013335202 0.880466046105246 -219.830597014925 92.9224139412476 -2.36574350246559 0.0185915129525828 IL4I1 other 1 1 1 -0.150499013335202 -2.36574350246559 0.644001057087492 -2.70471928499672 5.15868545561127 -0.524303974000724 0.600433544110732 -8.37739638603338 8.96203291039137 -0.934765188857976 0.350620825735845 TLE6 other 1 1 1 -0.524303974000724 -0.934765188857976 0.000299358905666671 61.1166571038964 22.6361416012747 2.69995912644648 0.00730947880526315 -113.345017920879 50.9190085150102 -2.22598635021471 0.0267223655560815 CCDC130 essential 1 1 1 2.69995912644648 -2.22598635021471 0.00107022337147016 270.870917968749 127.457366662114 2.12518840662087 0.0343391652049703 -745.89055640244 294.949970527902 -2.52887143900182 0.0119247024161888 PTOV1 other 1 1 1 2.12518840662087 -2.52887143900182 1.6701707752141e-07 118.598459830796 375.141057411927 0.316143641138612 0.752101542979273 -3195.63692264364 656.199412542225 -4.869917378108 1.76519653385482e-06 AES other 0.0018199850937508 0.0263667406261895 1 0.316143641138612 -4.869917378108 0.391879087940684 -1.0882622348942 3.67662807625887 -0.295994648444712 0.76742615948859 10.5500676666185 8.59889967154758 1.22690903134118 0.220758698014178 NOVA2 other 1 1 1 -0.295994648444712 1.22690903134118 2.08938069946886e-16 272.902755068744 84.1120141133521 3.24451575610793 0.00130166003749805 -844.540632645413 146.056201183701 -5.78229904516821 1.76073854028545e-08 SGTA other 2.92701342188592e-12 0.00026720968087372 1 3.24451575610793 -5.78229904516821 0.317110712490887 -14.1869357040739 10.7907835714314 -1.31472711042354 0.189543079645674 -30.449096643526 28.0426152562382 -1.08581515544462 0.278378059544356 LILRB1 other 1 1 1 -1.31472711042354 -1.08581515544462 0.281514952719011 -2.80670811813346 1.76296204827831 -1.59204114511396 0.112362770198026 -2.42118452235288 4.58150847933838 -0.528468851093893 0.597540275430632 LILRA1 other 1 1 1 -1.59204114511396 -0.528468851093893 2.76915898467809e-12 102.501193758349 19.9580297945006 5.13583729525214 4.89815307173727e-07 -109.620755525869 37.1472020518212 -2.95098283237982 0.00340224392485704 SNAPC2 essential 3.60959873652789e-08 1 0.00592235687903754 5.13583729525214 -2.95098283237982 6.58634272835344e-05 199.799248480972 69.6624125295287 2.86810693494545 0.00440797884489066 -411.720867875328 164.000895366893 -2.51047939070241 0.0125575067991208 C19orf53 essential 0.579071252676834 1 1 2.86810693494545 -2.51047939070241 5.59408045086248e-13 194.999123629784 43.0169174874944 4.5330798908702 8.23264526357043e-06 -314.64663450151 80.0659254449451 -3.92984447195164 0.000104259705356791 TIMM44 essential 7.40656251694192e-09 1 0.0929630303162373 4.5330798908702 -3.92984447195164 5.48991752340352e-05 23.7047614399757 11.7847314346947 2.0114808361426 0.0451127668193328 -94.1627583954469 27.5621360554332 -3.41638101655351 0.000716481791536228 CCDC61 other 0.487504676078233 1 1 2.0114808361426 -3.41638101655351 0.931582435868922 3.96365419135758 84.7005038754907 0.046796111120946 0.962705382322734 -73.4081425044994 210.096988024287 -0.349401213195943 0.727021585646691 IL27RA other 1 1 1 0.046796111120946 -0.349401213195943 0.0404048931624037 -25.1759593214659 67.6211628212502 -0.372308878923246 0.709913243698985 -424.48206007403 167.732209200653 -2.5307128672361 0.0118696899726563 ASF1B other 1 1 1 -0.372308878923246 -2.5307128672361 0.244810606555039 859.046984034429 584.663677034179 1.46930110040718 0.142733543538649 -630.877406085806 1525.80426016968 -0.413472043927605 0.679537748883476 TNNT1 other 1 1 1 1.46930110040718 -0.413472043927605 7.95979642348458e-07 44.2230643656716 19.670017508277 2.24824733109988 0.0252429126423016 -198.743718905472 46.0022104667779 -4.32030802191564 2.08379092898632e-05 VRK3 other 0.00829888375112503 0.304170961904133 1 2.24824733109988 -4.32030802191564 9.37431511685869e-11 224.246445005195 45.8128297612042 4.89483941887158 1.5672187663106e-06 -411.559853545101 112.873731103064 -3.64619694523351 0.000310832779759824 FAM32A essential 1.17328928002603e-06 1 0.0184884797861661 4.89483941887158 -3.64619694523351 5.07482168462146e-12 412.19678565317 73.5090265875078 5.6074308801039 4.44181466862838e-08 -652.091602388183 191.83744490012 -3.39918832179867 0.00076137772565564 PPP6R1 other 6.57899883194327e-08 1 0.00056069026562096 5.6074308801039 -3.39918832179867 2.67631822843376e-11 126.718120604742 22.8104526013752 5.55526551003651 5.87682660774741e-08 -167.010806447998 56.4038296237107 -2.96098345736777 0.00329806593757752 C19orf44 other 3.40775600026471e-07 1 0.000738540799795617 5.55526551003651 -2.96098345736777 1.45280610204294e-14 67.3611916982816 10.4946267807765 6.41863623217839 4.99283338845936e-10 -89.4093580302011 25.9618818418941 -3.44387046265356 0.000650298627508517 MED26 other 1.982644487458e-10 1 6.69189459055207e-06 6.41863623217839 -3.44387046265356 1.09766738043675e-05 360.293397513899 74.9189867486548 4.80910665173095 2.33778248969393e-06 153.158776311455 160.824170053573 0.952336805222964 0.341644967850052 OLFM2 other 0.104322307836709 1 0.0272959483496663 4.80910665173095 0.952336805222964 0.443060620582242 -20.0105096115793 16.7058684255051 -1.19781319365768 0.231876202983211 5.85926639264715 45.0221040588148 0.130141993919095 0.896535855796769 RASAL3 other 1 1 1 -1.19781319365768 0.130141993919095 3.09032547292493e-13 136.582510071532 21.4210693832541 6.37608270753772 6.36715682760518e-10 -172.506810163787 57.4995849302938 -3.00014009445313 0.00291116151180693 AKAP8 other 4.11415030210496e-09 1 8.51607225692192e-06 6.37608270753772 -3.00014009445313 0.00333635454753645 274.347133578683 87.3446499149925 3.14097238749814 0.00184163262021702 -116.190997179375 234.455200444851 -0.495578673277098 0.620532925893681 EPHX3 other 1 1 1 3.14097238749814 -0.495578673277098 2.30620641913968e-07 230.248069422036 61.3727609719372 3.75163290319166 0.000208643247652581 -484.505750590426 154.098832587601 -3.14412343334917 0.00182251212532118 ILVBL other 0.0024948541042253 1 1 3.75163290319166 -3.14412343334917 4.1358325348803e-05 31.2071514454714 7.17363387635546 4.35025706404271 1.83078152771919e-05 0.960180944954352 18.9708664952095 0.0506134469501861 0.959665125123323 ZNF419 other 0.372514436416668 1 0.201733816539377 4.35025706404271 0.0506134469501861 0.00162121809635341 79.5835767050968 21.9963862157382 3.61802961288958 0.000345017523785949 42.8323310630067 54.0679830317823 0.792193987296123 0.428836283357643 SYDE1 other 1 1 1 3.61802961288958 0.792193987296123 0.886007274104261 -146.554774814367 609.84848202626 -0.240313420683494 0.810241650644398 529.014329293385 1499.0315706751 0.352904061290144 0.72439343746899 CASP14 other 1 1 1 -0.240313420683494 0.352904061290144 0.217369717154528 14.0983292963262 8.22572717690458 1.71393105960408 0.0875127809999705 1.91135952096795 20.2191611414213 0.0945320880326886 0.924745843902261 SLC1A6 other 1 1 1 1.71393105960408 0.0945320880326886 0.588292905192275 3.72217197718102 6.60821997282424 0.563263933780676 0.573650865151453 -10.5786112657112 16.5220108684786 -0.640273835304972 0.522454205579823 AURKC other 1 1 1 0.563263933780676 -0.640273835304972 3.55474262887019e-06 76.8536532414268 24.460208471856 3.14198684487318 0.00184342909230052 -200.487379958141 64.7812344043358 -3.09483729048427 0.00215244427394335 POP4 essential 0.0352381636799902 1 1 3.14198684487318 -3.09483729048427 0.347179798621488 25.3506901452884 17.4332642852838 1.45415624580923 0.146934628252916 21.3675867473109 46.1708403424746 0.462793975349283 0.643843145998628 CCNE1 og 1 1 1 1.45415624580923 0.462793975349283 2.77372742386686e-08 221.588599657543 45.3858692058816 4.88232578850395 1.68651005725941e-06 -289.970581618358 127.9759968248 -2.26582006636236 0.0241563073466706 URI1 essential 0.000315095435351275 1 0.019862028944344 4.88232578850395 -2.26582006636236 1.70282259566552e-07 204.39521340547 42.7463203265439 4.7815861539443 2.66055742838124e-06 -238.324306807935 129.360339785122 -1.84232901060566 0.0663549560869056 PDCD5 other 0.00185471437119888 1 0.0309901729257846 4.7815861539443 -1.84232901060566 2.95958208340289e-11 218.485084159904 34.1493325240369 6.39793132138433 5.60996435346546e-10 -172.222525924256 103.343848663422 -1.66650002057851 0.096595385542954 ANKRD27 other 3.76399649367179e-07 1 7.51005927998421e-06 6.39793132138433 -1.66650002057851 1.38001119152421e-06 2372.23479678756 549.419736578035 4.31770946483032 2.10709184604164e-05 -3215.25415054185 1723.08263568319 -1.86598952595621 0.0629604014826226 RPS16 essential 0.0141464947243147 1 0.231190117347689 4.31770946483032 -1.86598952595621 1.00269355489743e-13 299.646931299003 44.6950035455739 6.70426015278114 9.19937168839973e-11 -376.488071162734 140.171856567877 -2.68590343583288 0.00761198153663364 TIMM50 other 1.34802121520411e-09 1 1.25074657475483e-06 6.70426015278114 -2.68590343583288 2.49227003616787e-07 973.846992792402 203.687160023833 4.78109171279356 2.66328740999282e-06 -1066.15003875335 638.932604734709 -1.66864240587006 0.0961663416380064 FBL essential 0.00269040550404322 1 0.0310193084641864 4.78109171279356 -1.66864240587006 0.000296854718009451 82.7275784162268 26.7345122322026 3.09441136227571 0.00214605744077723 -148.585258698414 83.8617001426823 -1.77178924879428 0.077381144144987 DYRK1B other 1 1 1 3.09441136227571 -1.77178924879428 0.105554410622439 9.0862653693464 4.53349184478028 2.00425316300239 0.0458852989994094 -2.20785770280411 13.5014365835549 -0.163527613461025 0.870206262409343 CNTD2 other 1 1 1 2.00425316300239 -0.163527613461025 5.74411573907441e-05 2195.55054686849 550.258788158526 3.99003267937988 8.19468430252166e-05 -1601.99922324247 1644.52315952947 -0.974142087303188 0.330721791212298 GPI other 0.50869888985243 1 0.85691813751469 3.99003267937988 -0.974142087303188 3.56219890495869e-22 515.572299333873 58.23148412188 8.85384096092703 5.9056400239183e-17 -618.73910573775 173.422323664938 -3.56781694917886 0.000415041214711431 AKT2 og 5.24284434831819e-18 1 8.62223443492072e-13 8.85384096092703 -3.56781694917886 1.05101455624674e-06 1008.47654208051 231.751866165351 4.35153579890043 1.82072993787374e-05 -1276.06372190277 679.768511060012 -1.87720334369845 0.0613998116516864 PLD3 other 0.0108632864533663 1 0.200662646453065 4.35153579890043 -1.87720334369845 4.02677289216013e-05 27.5797177208574 6.25474577309962 4.40940666836885 1.41725469438186e-05 -0.0296915838996279 18.3462566735289 -0.00161840011442055 0.998709712530272 PRX other 0.363214914872844 1 0.157315271076386 4.40940666836885 -0.00161840011442055 1.73166335603543e-18 86.1311658203579 22.8149097704937 3.77521395818757 0.000190628077655534 -257.308613898716 41.9772386153723 -6.12971749419667 2.5964138930987e-09 PIAS4 other 2.47991509217834e-14 3.95667513169312e-05 1 3.77521395818757 -6.12971749419667 5.31382387496331e-18 289.113891792996 30.9357102223197 9.34563615043188 1.61918976757702e-18 72.2352848928386 90.7398159262561 0.796070436725858 0.426581248701415 NUMBL other 7.57538731614769e-14 1 2.38700955536205e-14 9.34563615043188 0.796070436725858 0.470999569383536 -4.86469049029042 8.20724775610957 -0.592731039058628 0.553779793689076 10.2897354409451 15.1982738055752 0.677033166567281 0.498874039489235 EBI3 other 1 1 1 -0.592731039058628 0.677033166567281 5.15073467899463e-10 72.8623746271981 24.4945623469286 2.97463467994293 0.00315649427133916 -181.235875043878 45.3593063544631 -3.99556099089346 8.01468817491316e-05 CCDC94 essential 6.30140880628203e-06 1 1 2.97463467994293 -3.99556099089346 1.52199719742025e-08 232.315655739879 56.8102120448957 4.08932914308233 5.49012067887659e-05 -518.859415627458 160.15814861637 -3.23966916519679 0.00132366934001047 TBCB essential 0.000175090557591226 1 0.58321551971706 4.08932914308233 -3.23966916519679 0.0567712468583591 16.0561751528281 6.69062310934535 2.3998026626849 0.0169751124922555 11.7553069873769 12.3981373725976 0.948151051573162 0.343768029537566 FSD1 other 1 1 1 2.3998026626849 0.948151051573162 0.0003781977347421 52.4789322739445 37.1410714983974 1.4129622586739 0.158647912462979 -334.108723607343 104.707323466961 -3.19088209443885 0.00156041114301774 POLR2I essential 1 1 1 1.4129622586739 -3.19088209443885 0.288129091900837 31.0426729694419 28.1299395068543 1.10354567104127 0.270624647155549 -116.939043607916 130.178673280249 -0.898296477151588 0.369707145104651 CLIP3 other 1 1 1 1.10354567104127 -0.898296477151588 0.071920598226716 10.6060622847985 17.878630505251 0.593225654598293 0.553451816245127 -54.299412493324 32.0336897351935 -1.69507206138881 0.0910406448239106 ZFR2 other 1 1 1 0.593225654598293 -1.69507206138881 0.00224119883029607 762.370995047642 314.808132810522 2.42170044414482 0.0160035814152097 -1353.66892855477 712.948589225934 -1.89869080184938 0.058504515495551 SLC1A5 other 1 1 1 2.42170044414482 -1.89869080184938 5.93329689026536e-09 238.880191449852 60.9953594409177 3.91636664886352 0.000109908471767835 -543.478806185243 139.572279675064 -3.89388786548811 0.00012010308600837 PRKD2 other 6.9627239007264e-05 1 1 3.91636664886352 -3.89388786548811 0.0424318830151907 -22.2984308270875 57.491342360222 -0.387857195738669 0.69838202782539 -244.818125461485 102.324268083569 -2.39257147934388 0.0173126533374136 TJP3 other 1 1 1 -0.387857195738669 -2.39257147934388 0.619387899581892 0.904827494891965 9.19158544096417 0.0984408512224036 0.921643871273349 -40.2203302682355 42.9089131720138 -0.937342088041237 0.349289511439359 APLP1 other 1 1 1 0.0984408512224036 -0.937342088041237 1.59060602295733e-19 129.56043996607 23.5545404763285 5.50044438762341 7.81387816667265e-08 -203.036971204866 41.8647713209307 -4.84982874141142 1.9399772007379e-06 CACTIN other 2.29985724859401e-15 0.0289580396754146 0.000977281742305749 5.50044438762341 -4.84982874141142 1.50681627871071e-08 109.310649356406 22.5007105793548 4.85809765744474 1.85853483904471e-06 -128.267821371472 50.9575458579 -2.51715068322088 0.0123190906904378 CCDC9 other 0.000173404417354029 1 0.0218154819407068 4.85809765744474 -2.51715068322088 6.9667671919715e-08 1143.27859664422 242.06547644663 4.72301384495977 3.48717583419622e-06 -1322.3509630462 632.075915229111 -2.09207617500642 0.0372219234730562 HNRNPUL1 other 0.000774286505715712 1 0.0403257013466451 4.72301384495977 -2.09207617500642 5.37371855972436e-22 313.081365475552 61.7827364181596 5.06745708633794 6.86259882628201e-07 -650.636557305122 109.746180408035 -5.92855764898665 7.97901000398357e-09 FZR1 other 7.89775416722689e-18 0.000121328826120574 0.00823854989095155 5.06745708633794 -5.92855764898665 0.00941653707125849 428.650062889388 155.934483838177 2.74891128850129 0.00631997705140011 -234.216059853932 407.172608976009 -0.575225481013955 0.565544311240566 TGFB1 other 1 1 1 2.74891128850129 -0.575225481013955 0.145529065672847 27.8974581544158 19.5655707704612 1.42584433041604 0.154891092190954 -121.657890607254 100.19615936809 -1.21419714462627 0.225570551985271 DENND3 other 1 1 1 1.42584433041604 -1.21419714462627 0.0339651248022452 -2.59944265560855 1.42367418773185 -1.82586906330717 0.0688105988623835 -8.63651565510017 3.7569336116606 -2.29882040723172 0.022165312567923 CEACAM4 other 1 1 1 -1.82586906330717 -2.29882040723172 0.000154007049569322 474.339543397249 220.045186669617 2.15564607695527 0.0318565476023417 -971.255313049813 417.608337833472 -2.32575651647338 0.0206561537828375 PLIN3 other 1 1 1 2.15564607695527 -2.32575651647338 0.180747996725977 768.4936312891 547.024424269821 1.40486164272263 0.161032390850201 -1137.46947420672 1300.54680086925 -0.874608644184475 0.382442819490969 MYH14 other 1 1 1 1.40486164272263 -0.874608644184475 4.68463062300459e-10 435.544280382932 86.6406742070714 5.02701859569998 8.32126885494104e-07 -498.244036994971 186.412670397691 -2.67280134945775 0.00790882231885027 MRPL4 essential 5.73914097624292e-06 1 0.00995723031182245 5.02701859569998 -2.67280134945775 0.189591637527347 -0.27927684835403 3.56781174767901 -0.0782767892772678 0.937656803429305 -15.5788720992985 8.65852559926115 -1.79925230002529 0.072920797981864 SIGLEC8 other 1 1 1 -0.0782767892772678 -1.79925230002529 0.143991457962894 -63.1160906409635 53.0874084705859 -1.188908866703 0.235365366900512 -258.518329191644 141.112780543057 -1.83199798201669 0.0678898267957282 CD79A og 1 1 1 -1.188908866703 -1.83199798201669 0.433859733858649 22.2126183135919 27.7731864651078 0.799786453797737 0.42442968761667 -41.9727297311916 59.7556967532368 -0.702405494567646 0.482938534149893 ICAM4 other 1 1 1 0.799786453797737 -0.702405494567646 0.0108192122205882 2269.7955101368 1533.00529966975 1.48061817570087 0.139701544222298 -8831.5045499502 4074.91430936021 -2.16728595486387 0.030957296825657 RPS19 essential 1 1 1 1.48061817570087 -2.16728595486387 0.00348682300069652 797.925883620556 277.326622774783 2.87720621856255 0.00428169312114764 -683.624712488527 631.48215408525 -1.08257170541709 0.279813642349185 NOP53 other 1 1 1 2.87720621856255 -1.08257170541709 0.0471224319514768 -59.2744918150748 44.8703775801126 -1.32101611378787 0.187439837278879 -255.052379025005 108.893445170884 -2.34221976010363 0.0197821404747913 NKG7 other 1 1 1 -1.32101611378787 -2.34221976010363 0.0784542137580232 25.7546649359079 11.5144420544303 2.2367271305168 0.0259949016043102 9.59903726540105 24.7740211067129 0.387463836575163 0.69867124133663 ICAM5 other 1 1 1 2.2367271305168 0.387463836575163 0.0597018598114426 350.628830384117 223.989790679949 1.56537862426559 0.118482491653789 -768.282952093224 543.498777062368 -1.41358726922225 0.158455166288254 ETFB other 1 1 1 1.56537862426559 -1.41358726922225 0.367297461520152 0.0943569270608503 4.53980217508054 0.0207843697636839 0.983430619763959 -15.186383254208 11.0155776420493 -1.37862795285811 0.168972475840066 CD33 other 1 1 1 0.0207843697636839 -1.37862795285811 0.837208450578687 -300.382376459513 661.741562304081 -0.453927021620992 0.650191970608578 -865.571255133943 1759.35793616594 -0.491981328722812 0.623073058045225 CEACAM5 other 1 1 1 -0.453927021620992 -0.491981328722812 0.000188044378280366 75.1772411161281 65.5768309308022 1.14639942261706 0.252489105329334 -542.180670751449 153.87110825252 -3.52360281867646 0.000487930251048256 BABAM1 other 1 1 1 1.14639942261706 -3.52360281867646 0.0140980273402635 188.665701573914 117.092162108946 1.6112581591787 0.108109329567067 -451.234886243386 253.134227208556 -1.78259135960945 0.0756007970390935 TYK2 other 1 1 1 1.6112581591787 -1.78259135960945 4.63630259960058e-09 235.181682492036 122.092977078731 1.92625069941885 0.0549586228506488 -1503.59848146638 276.504977763924 -5.4378712948529 1.07217757486099e-07 NAPA essential 5.46759165570896e-05 0.00162059640440239 1 1.92625069941885 -5.4378712948529 0.000922516829810386 367.535816129602 125.061462264886 2.93884150619591 0.00353621965171432 -457.767728037725 309.858902558892 -1.47734250737147 0.140576631945302 RABAC1 other 1 1 1 2.93884150619591 -1.47734250737147 0.864580231801122 -3.87914525201731 12.9660811432238 -0.299176382529781 0.765001514390687 -16.5134619103856 32.1254493652032 -0.514030534566536 0.607588774801739 ATP1A3 other 1 1 1 -0.299176382529781 -0.514030534566536 0.126956965426404 41.4257115644841 20.3336602747445 2.03729731906346 0.042442717015374 19.9722996421575 46.0498090606951 0.433710802488528 0.664790701172804 MEIS3 other 1 1 1 2.03729731906346 0.433710802488528 0.000415315335253803 279.73047219968 120.693657987961 2.31768990072024 0.0210986017910707 -406.927346938626 221.419780800521 -1.83780936584536 0.067020317637513 PTPRS other 1 1 1 2.31768990072024 -1.83780936584536 0.361831447928598 -472.951796978835 884.197206404217 -0.534894018611751 0.593098134310606 -3111.45783354387 2190.7338284735 -1.42028109170703 0.156508626540657 CNFN other 1 1 1 -0.534894018611751 -1.42028109170703 1.24113361649336e-05 228.0784203087 69.5446994739244 3.27959459216898 0.0011551918906671 -434.036320719778 172.307630724293 -2.51896169017769 0.0122618092470301 MEGF8 other 0.117473296801096 1 1 3.27959459216898 -2.51896169017769 4.60560486617852e-13 971.869140624998 133.715469222623 7.26818778915496 2.80825229189629e-12 -414.593750000001 306.359613642044 -1.35329113740305 0.176917841391717 KDELR1 other 6.10841373401258e-09 1 3.9180735976537e-08 7.26818778915496 -1.35329113740305 5.20674883508124e-08 220.536894531249 51.1128764718625 4.31470325589393 2.13250002875871e-05 -354.060401785715 117.106279318982 -3.02341090370825 0.00270149604158128 CYTH2 other 0.000582947599575696 1 0.233892603154255 4.31470325589393 -3.02341090370825 6.34872432995959e-10 240.632558593749 44.8144135143394 5.36953492689921 1.52033039680111e-07 -282.626443452382 102.675677613559 -2.75261337466995 0.00624955448299383 GRWD1 essential 7.73465085118977e-06 1 0.00187988853564457 5.36953492689921 -2.75261337466995 0.00113975809611337 143.24728515625 38.6418858675588 3.70704695022431 0.00024705552554452 45.7382291666668 88.5336101620046 0.516619948999844 0.605778326459714 GRIN2D other 1 1 1 3.70704695022431 0.516619948999844 0.000979829832903708 117.043101187577 33.9660078590047 3.44588924531346 0.000645138442457885 179.95525044019 80.7539497313916 2.2284389932476 0.0265456964547699 CLEC11A other 1 1 1 3.44588924531346 2.2284389932476 0.429393527183907 -8.49187499999998 7.71081275370097 -1.10129441230746 0.271596218028092 -16.3109523809524 17.6664796513334 -0.923271229065796 0.35656150649824 CCDC114 other 1 1 1 -1.10129441230746 -0.923271229065796 0.0117300984035068 11.8327148437499 16.568424399245 0.714172606798337 0.475641056229444 -101.842038690476 37.9604254251182 -2.68284766437544 0.0076790991474514 CARD8 other 1 1 1 0.714172606798337 -2.68284766437544 0.00273123987094371 44.7021874999997 87.6350345543559 0.510094937798799 0.610336597775613 -648.370714285716 200.783316123885 -3.22920612530209 0.00137018930611141 LIG1 other 1 1 1 0.510094937798799 -3.22920612530209 0.0150069586520748 13.3387839539485 6.82270382084854 1.9550583323269 0.0514464425591811 -27.8536877136177 16.5576436950251 -1.68222533511737 0.0935006354522164 ZNF175 other 1 1 1 1.9550583323269 -1.68222533511737 0.00205948625171416 63.5161914540716 23.5099798087656 2.7016693323739 0.00726694854179642 -88.0387861486908 53.567131557261 -1.64352250324588 0.101256988964094 PLA2G4C other 1 1 1 2.7016693323739 -1.64352250324588 0.0724609216430364 -4.08768663428675 2.66509558062293 -1.5337861291006 0.126070329338351 -13.0000112430294 6.46777350971868 -2.00996698840724 0.0452736563999586 SIGLEC5 other 1 1 1 -1.5337861291006 -2.00996698840724 0.000249702411232526 53.9398400954207 13.0859489920959 4.12196625005962 4.79428552065933e-05 22.4873623199209 31.2716589410046 0.719097197956282 0.472607463637548 HAS1 other 1 1 0.512509122158482 4.12196625005962 0.719097197956282 1.50016304341361e-05 366.244433257272 105.05320097703 3.48627580931447 0.000558656693885519 -451.619363477986 221.648844816898 -2.03754440430792 0.0424230064239429 RAB3D other 0.141043398117029 1 1 3.48627580931447 -2.03754440430792 0.000208383052369642 46.0476367187498 34.8860376634635 1.31994459109858 0.187796959779107 -284.757574404763 79.92847112017 -3.56265508915639 0.000422970316051453 DBP other 1 1 1 1.31994459109858 -3.56265508915639 0.00577773083865605 19.3374146837539 82.9569201612813 0.233101887656375 0.815832257834863 -523.866221934392 175.028512718389 -2.99303361377047 0.00297857876542131 TMEM205 other 1 1 1 0.233101887656375 -2.99303361377047 0.428210082740547 -112.209484857197 117.11740536649 -0.958094012636855 0.338740915134502 -257.628173130827 212.46417588179 -1.21257229394835 0.226190624347309 CAPS other 1 1 1 -0.958094012636855 -1.21257229394835 2.13631350878322e-05 143.254089361336 34.4541684119398 4.15781590339278 4.13679834751064e-05 -59.1949021909432 72.6938975358121 -0.814303596278921 0.416080411510134 PLPPR2 other 0.197865357183502 1 0.444498982440019 4.15781590339278 -0.814303596278921 0.169134915951256 -23.37287109375 41.6566675866225 -0.56108355391481 0.575133258275713 -179.911889880953 95.4408690456399 -1.88506131262194 0.060327469511085 FAM83E other 1 1 1 -0.56108355391481 -1.88506131262194 0.0941753739858071 29.8215429687499 72.7363318999251 0.409995145339197 0.682083849507663 -332.786502976191 166.648441411821 -1.99693738601377 0.0466786203507668 RASIP1 other 1 1 1 0.409995145339197 -1.99693738601377 0.00396012954025015 103.629453125 52.8813274014205 1.95966058753314 0.0509032142680752 -268.480178571429 121.158031496004 -2.21595031923479 0.0273981815512736 BCAT2 other 1 1 1 1.95966058753314 -2.21595031923479 5.18893062793617e-12 81.2354499158821 26.5884846929827 3.05528693544999 0.00243938285844919 -188.228371906212 43.4675538390351 -4.33031894555746 1.9998680394146e-05 MIER2 other 6.72537298686807e-08 0.292060728476108 1 3.05528693544999 -4.33031894555746 0.00237707159071724 137.35447265625 50.5653795104971 2.71637381121081 0.00695894917417414 -180.483913690477 115.851892234756 -1.55788490122159 0.120248949647208 PLEKHA4 other 1 1 1 2.71637381121081 -1.55788490122159 3.58707173801299e-15 1104.08955629544 164.533220273634 6.710435463788 8.94276909176657e-11 -1542.7626140004 409.921762672173 -3.76355381559527 0.00019955697537224 PPP2R1A other 4.94190873346049e-11 1 1.21603774109842e-06 6.710435463788 -3.76355381559527 1.05650144658929e-16 398.699024215034 54.542740768815 7.30984579423612 2.21955504607754e-12 -696.848022987817 180.901152749585 -3.85209277219167 0.000141895490128475 TNPO2 other 1.48396193187931e-12 1 3.10227208790257e-08 7.30984579423612 -3.85209277219167 0.000166306599541258 107.753712322023 75.8829843593512 1.41999834655613 0.156600244175419 -566.098051379553 165.058530983824 -3.42968065937187 0.000685032396074433 WDR83OS other 1 1 1 1.41999834655613 -3.42968065937187 3.14797440613775e-05 52.6575054443952 17.8721386475064 2.94634606875894 0.00345533673496986 -171.876089179791 59.1366262704182 -2.90642365010545 0.00391499522124874 GCDH other 0.286906387375394 1 1 2.94634606875894 -2.90642365010545 0.51219294962626 -7.13158601148316 8.24819358292143 -0.864623985820325 0.38789694532474 -19.8366258212579 20.3476100812348 -0.974887259096429 0.330357187227035 LILRB5 other 1 1 1 -0.864623985820325 -0.974887259096429 0.00339899649679779 141.50102270403 48.3232736149418 2.92821682222036 0.00365758464022272 -177.399809095248 159.895546262936 -1.10947311067393 0.268072418203308 DNASE2 other 1 1 1 2.92821682222036 -1.10947311067393 0.0804528521270483 4.8718612010155 4.23766911300957 1.14965587710918 0.251157742588622 -23.396468262085 14.0219063614251 -1.66856543318887 0.0961971416998015 MAST1 other 1 1 1 1.14965587710918 -1.66856543318887 0.00754413388418313 46.5671165461187 19.3101065823181 2.41154114544139 0.0164515965924976 -62.0265312885775 47.636432803621 -1.30208178148601 0.193830760949959 LENG1 other 1 1 1 2.41154114544139 -1.30208178148601 9.6201140572314e-05 210.015223480905 66.1352760262138 3.1755401368199 0.0016425976474661 -325.834646046791 160.837323232991 -2.02586464072635 0.0436159590246202 PRPF31 essential 0.830504446560787 1 1 3.1755401368199 -2.02586464072635 0.0566263821503497 51.4493675004108 26.3752998751253 1.95066474102662 0.0519778492227449 -53.3518368856499 64.1432664422714 -0.831760523665665 0.406170237752071 TFPT other 1 1 1 1.95066474102662 -0.831760523665665 0.707864245183923 -28.0365142489927 52.3459176694016 -0.535600778384696 0.592608874076578 -91.4570294985213 118.980147592258 -0.768674702034681 0.442656932854125 JAK3 og 1 1 1 -0.535600778384696 -0.768674702034681 0.000554062668896387 433.79066840341 206.410215287206 2.10159496127563 0.0363752170134081 -1180.05260975408 469.162046876812 -2.51523459241775 0.0123880169800114 RPL18A essential 1 1 1 2.10159496127563 -2.51523459241775 0.37673483178734 52.736413264023 42.6950281463306 1.23518862859809 0.217672111332351 -24.5213733778431 97.0440671684972 -0.252682869682973 0.800676540608219 SLC5A5 other 1 1 1 1.23518862859809 -0.252682869682973 0.0532199164300206 11.9680513626153 5.00750782450013 2.39002150012817 0.0174274421275423 3.31152624543147 11.5671268625423 0.286287708675103 0.774843604983681 KCNN1 other 1 1 1 2.39002150012817 0.286287708675103 0.330033631794948 -2.89055571320643 114.852110955937 -0.025167632437469 0.979936990488988 -379.208445445813 265.303417272389 -1.4293387146856 0.153885445336068 ARRDC2 other 1 1 1 -0.025167632437469 -1.4293387146856 8.91517956703666e-05 456.871956627748 181.768172032837 2.51348710568104 0.0124483283077492 -1126.18311118335 421.391263582651 -2.6725354996888 0.00791618183783673 PIK3R2 other 0.771876246914034 1 1 2.51348710568104 -2.6725354996888 0.000253766219388735 7.12985251707289 3.72947097198884 1.91175975644361 0.0568055530141187 -25.6946009884609 8.74019658398303 -2.93981957288557 0.00352460370454905 RAB3A other 1 1 1 1.91175975644361 -2.93981957288557 0.13275639755431 134.790195351293 111.473566576904 1.209167334377 0.227499624424821 -311.044070321438 261.190137284871 -1.19087218818754 0.234594711514413 ISYNA1 other 1 1 1 1.209167334377 -1.19087218818754 2.67645904381798e-10 109.422277745973 22.9262457405647 4.77279529253087 2.7783487439562e-06 -183.166772780046 53.7362310624237 -3.40862708750949 0.000737235022232532 ELL other 3.30756808635027e-06 1 0.0323121958922106 4.77279529253087 -3.40862708750949 7.37286572219181e-05 66.8392418782945 19.2179227154389 3.47796392294774 0.000575149909399973 -73.8412895719723 45.5150689356538 -1.62234818706667 0.105713576913219 CRTC1 og 0.644830836062895 1 1 3.47796392294774 -1.62234818706667 0.472020980199293 102.209281486971 118.45754873759 0.862834682772197 0.388874553894802 -160.481660959519 279.122742492725 -0.574950143891274 0.565729022932929 COMP other 1 1 1 0.862834682772197 -0.574950143891274 0.381699990278912 2.06761920584813 5.22230158830139 0.39592106485766 0.692427931564316 35.4421173229217 25.6368017355503 1.38247031312702 0.167794433294156 UPK1A other 1 1 1 0.39592106485766 1.38247031312702 1.10501402727009e-06 214.38740162107 123.208072228034 1.74004347072553 0.0828127665602035 -1251.67635412824 290.316449935263 -4.31142070801482 2.1626380664643e-05 COPE essential 0.0114070598035091 0.315485641135813 1 1.74004347072553 -4.31142070801482 9.71871985028409e-07 135.460543152892 56.2844705878688 2.40671257521055 0.0166630719964651 -513.554195324818 132.623677913839 -3.87226627554739 0.000130749184803026 DDX49 essential 0.0100724812528344 1 1 2.40671257521055 -3.87226627554739 0.00152143838106763 3.15329235199644 1.10972258730126 2.841514075752 0.0047789417682275 -9.33130330342799 5.44773936760666 -1.71287623613453 0.0877069658477559 ETV2 other 1 1 1 2.841514075752 -1.71287623613453 3.90736331595617e-13 152.630881268603 30.585284746948 4.99033710267594 9.92884652260837e-07 -314.440599853515 72.0558458514783 -4.36384579401983 1.72819924083692e-05 ARMC6 other 5.19015069258458e-09 0.252904676904075 0.011842135247515 4.99033710267594 -4.36384579401983 9.10525870604708e-58 676.98047111804 34.2344607922377 19.7748249994794 1.98771337472532e-57 -50.6666284596451 169.367800106984 -0.299151482322145 0.765018657892914 TMEM147 other 1.39692879068174e-53 1 3.04994740217853e-53 19.7748249994794 -0.299151482322145 5.2900958851934e-47 12.9261376211234 0.746670725716253 17.311697346543 7.60115443630301e-48 5.36678315562823 3.69399649628836 1.45283926528372 0.147248257723609 GAPDHS other 8.10019481940814e-43 1 1.16457287118598e-43 17.311697346543 1.45283926528372 0.0831086236562504 20.359650055909 9.47785616862473 2.1481281941487 0.0324562992665857 0.347144454542022 22.4427436628176 0.0154680042581941 0.987668479857034 TMEM59L other 1 1 1 2.1481281941487 0.0154680042581941 1.61089521328052e-47 594.38536843974 36.284987115722 16.3810274079496 3.17387506928868e-44 -551.558727332697 177.255364549487 -3.11166169066049 0.00202803356873862 USF2 other 2.46724710866044e-43 1 4.85856795606711e-40 16.3810274079496 -3.11166169066049 2.94628241595432e-23 1211.54734883051 115.099135466574 10.5261203215758 1.90588064504794e-22 -797.15458854427 562.269435328485 -1.41774483629643 0.157238266869816 LSR other 4.36197111682037e-19 1 2.8546280301528e-18 10.5261203215758 -1.41774483629643 1.98020445545976e-10 162.049418908205 39.6428089778656 4.08773805606673 5.51408055460428e-05 -385.475754860694 92.492967441174 -4.16762231253806 3.96557756859961e-05 KXD1 other 2.45723570878002e-06 0.574057008830479 0.58565049570452 4.08773805606673 -4.16762231253806 0.000164588153939553 328.832089671487 199.537696841542 1.64796975647474 0.100343424240804 -1513.54338075055 465.464043500446 -3.25168700329287 0.00126990397387726 FKBP8 other 1 1 1 1.64796975647474 -3.25168700329287 7.88209607441776e-07 37.5015230805277 20.6320275794739 1.8176363392339 0.0700577165665211 -202.748951502536 46.9572400659713 -4.31773569353075 2.10685541656e-05 SUGP1 essential 0.0082226026248326 0.307474479492767 1 1.8176363392339 -4.31773569353075 2.97956137042851e-05 80.8735018846524 17.7332058591673 4.56056860372173 7.2828856759344e-06 19.8602475664203 57.3627774568255 0.3462218610556 0.72940422803476 HPN other 0.272421296098278 1 0.0825442262510405 4.56056860372173 0.3462218610556 1.59061667820965e-07 36.4714533179413 7.47987401484632 4.87594486826268 1.71342238138136e-06 -22.8655128886441 16.937934615804 -1.34995874097361 0.177989317508135 ZNF14 other 0.00173520373425891 1 0.0201635545840958 4.87594486826268 -1.34995874097361 0.0577428829333533 51.6346321556585 23.6949480021616 2.17914097768638 0.0300525344595942 -34.1248719130218 80.0787699518684 -0.426141309782015 0.670292276302382 SCN1B other 1 1 1 2.17914097768638 -0.426141309782015 0.159107408718663 2.26923024420872 5.23713924975013 0.433295762436905 0.665093675914501 -19.718613920854 11.9125211346709 -1.6552846956522 0.0988532696062672 PBX4 other 1 1 1 0.433295762436905 -1.6552846956522 8.01451887492035e-06 290.867139503495 67.9809558246538 4.27865622033531 2.49299637164681e-05 -200.123600932437 168.43321663804 -1.18814806798174 0.235664483897485 ERF other 0.0771557732088582 1 0.272135483928966 4.27865622033531 -1.18814806798174 2.16440459459873e-12 280.62374032483 48.2107269185811 5.82077388708017 1.43457225950235e-08 -378.968137264987 119.449450406372 -3.17262353217801 0.00165866756526125 GSK3A other 2.82995900743785e-08 1 0.000184471646849408 5.82077388708017 -3.17262353217801 2.09344858072137e-11 229.126047015506 53.7716470249376 4.26109408382533 2.68339361475594e-05 -522.952310489827 121.764168712566 -4.29479637580657 2.32562566766807e-05 ATP13A1 other 2.67165907871661e-07 0.338959941062621 0.292328900391512 4.26109408382533 -4.29479637580657 8.00877615971298e-11 110.728418868483 19.9298677709127 5.55590333770752 5.85730513601896e-08 -132.606272040457 49.3792959381758 -2.6854629966066 0.00762421212909535 ZNF574 essential 1.00510140804398e-06 1 0.000736146109494863 5.55590333770752 -2.6854629966066 0.496831397408364 13.532777786922 15.4859073782399 0.873876968032086 0.382846788554504 -20.250746340821 38.3687043030627 -0.527793333360088 0.598012017263014 GRIK5 other 1 1 1 0.873876968032086 -0.527793333360088 2.41379235505379e-06 322.870041712482 79.8567106151087 4.04311721864732 6.61404606396087e-05 -470.665226343741 233.455306926681 -2.01608278920624 0.0446266487614207 SIPA1L3 other 0.0242465442065153 1 0.698310983432988 4.04311721864732 -2.01608278920624 0.0386250327649054 4.59152412622581 4.43462072011713 1.03538147138422 0.301277500114157 -18.9760381622989 10.0810693222591 -1.88234378275722 0.0607022503069447 ZNF85 other 1 1 1 1.03538147138422 -1.88234378275722 0.00924771172250044 22.2847139748524 55.4246030665836 0.402072594874175 0.687900708768284 -393.894594791323 137.903860698676 -2.85629853142396 0.0045681993663068 ETHE1 other 1 1 1 0.402072594874175 -2.85629853142396 0.000493978122769802 149.769662450111 47.5175442716148 3.15188136815348 0.00177671225155222 -363.072853282321 199.111006919091 -1.82346952536811 0.0691709263975556 CADM4 other 1 1 1 3.15188136815348 -1.82346952536811 1.40857216822509e-06 97.8733713243852 22.9501496173575 4.26460711394937 2.64377804534054e-05 -230.834752579157 96.1671624513132 -2.40034900370511 0.0169538654502438 SMG9 other 0.0144251875747932 1 0.288066055820306 4.26460711394937 -2.40034900370511 1.88754872278447e-14 205.247223580789 26.3855139384825 7.77878437612852 1.01613695221952e-13 -171.673765882427 108.506685776481 -1.58214919803254 0.114603338758992 AVL9 other 2.57084136043244e-10 1 1.44636933778927e-09 7.77878437612852 -1.58214919803254 0.812025191857988 0.341988960280149 1.36803325757501 0.249985852600077 0.802762282104567 -2.7059542894869 5.28404910047097 -0.512098627025574 0.60894312039893 RUNDC3B other 1 1 1 0.249985852600077 -0.512098627025574 0.838017803188825 0.909188256511633 1.94502475777851 0.467443025018382 0.64050512260563 -2.14325165608851 8.40297493195245 -0.255058675462515 0.798843700515509 CFAP69 other 1 1 1 0.467443025018382 -0.255058675462515 1.12477683828e-08 670.565744055443 116.782266809684 5.7420168521668 2.23078471218283e-08 -549.783227017959 504.219073343313 -1.09036578757826 0.276398848384035 CDK6 og 0.000130159175725762 1 0.000284848899898626 5.7420168521668 -1.09036578757826 1.6390576745113e-13 243.261909806083 31.3402068288423 7.76197525225678 1.15289243315676e-13 -17.976900696298 123.591335145476 -0.145454377324574 0.884444286080864 PMPCB essential 2.19469822617063e-09 1 1.63918246146228e-09 7.76197525225678 -0.145454377324574 7.30618239076793e-19 283.316276798355 29.6566757668303 9.55320410911436 3.54020006435949e-19 39.1297652533194 116.95226435538 0.334578945255962 0.738163295821135 DNAJC2 other 1.05019065684898e-14 1 5.23524785517481e-15 9.55320410911436 0.334578945255962 0.415562784266897 70.1732787256271 77.9231449687063 0.900544745130712 0.368527232293948 -252.253749649328 336.854050254879 -0.748851763719217 0.454512542898809 TFPI2 other 1 1 1 0.900544745130712 -0.748851763719217 3.8307071386017e-07 45.1340399530533 8.90669028681841 5.06743116686679 6.94215787774195e-07 -43.2235350345445 38.7313036647739 -1.11598451238956 0.265293060747896 BET1 other 0.00408698144617415 1 0.00833058945329034 5.06743116686679 -1.11598451238956 5.00224174845005e-06 1452.36924763483 310.03872439423 4.68447691646436 4.17548518893089e-06 -536.4674198399 1046.82383387894 -0.512471537691357 0.608679043800655 NAMPT other 0.0490419781018043 1 0.0480431325838388 4.68447691646436 -0.512471537691357 1.69404825288669e-20 144.564845056231 14.9051036952068 9.69901639146064 1.14393583856851e-19 -95.5525336033856 63.0455167348532 -1.51561187142371 0.130604675054703 TWISTNB essential 2.46704247067888e-16 1 1.69508412559081e-15 9.69901639146064 -1.51561187142371 0.00923153336260357 -12.0261235549816 7.13178505397268 -1.68627117390233 0.0927337054353039 -68.8755939120028 23.3886906281966 -2.94482470211346 0.00347190732596708 PIK3CG other 1 1 1 -1.68627117390233 -2.94482470211346 0.626407605920266 -7.96053642840493 9.82857466052801 -0.80993803306748 0.418589157228155 -29.3974178987091 41.972558477885 -0.700396138924873 0.484198575785148 PON3 other 1 1 1 -0.80993803306748 -0.700396138924873 0.00108786735616176 121.212874128006 34.8294351522298 3.48018489528234 0.00057196043433625 -78.4828111830422 148.737793034187 -0.527658838967734 0.598108795216227 PON2 other 1 1 1 3.48018489528234 -0.527658838967734 0.0138790851047608 270.039336298597 110.390735447194 2.44621376245629 0.0149745651547042 -542.421228832019 466.930059751739 -1.16167553898847 0.246233022926346 ITGB8 other 1 1 1 2.44621376245629 -1.16167553898847 1.22346640679338e-05 216.814546912249 52.0105639551979 4.16866364108287 3.96381931385348e-05 -210.032988279032 170.568655748891 -1.23136919474959 0.219103337357746 HBP1 other 0.115886738051469 1 0.426506958170634 4.16866364108287 -1.23136919474959 1.85835358631206e-30 55.8439471027876 4.44616242084474 12.5600330840315 1.26178295144337e-29 -18.1380888151758 19.8186570748837 -0.915202717653473 0.360783058756077 DUS4L other 2.81038812857973e-26 1 1.91551269858618e-25 12.5600330840315 -0.915202717653473 0.163641293568409 4.52960015216146 7.6704146933493 0.590528717578841 0.555253050347384 -54.34487438329 32.4442733040716 -1.67502208707106 0.0949067888819545 SP4 other 1 1 1 0.590528717578841 -1.67502208707106 1.98478902615908e-08 205.080691933044 57.4018578013457 3.57271872005919 0.000407998716277471 -346.481601821271 126.211943009152 -2.74523625546394 0.00639060064487478 WDR91 other 0.000227357582946523 1 1 3.57271872005919 -2.74523625546394 0.0393764728697681 29.3774927035768 17.6970444679978 1.66002253973545 0.0978894876723879 -120.217700074924 74.8548507933822 -1.60601081694431 0.109257850331161 DNAH11 other 1 1 1 1.66002253973545 -1.60601081694431 4.1785021547873e-24 133.459511691567 12.9819625610944 10.2803802632686 1.41409587715451e-21 -138.965229006681 57.1499056548511 -2.43159157332545 0.0155880720051734 CBLL1 essential 6.2038221492127e-20 1 2.1132248788197e-17 10.2803802632686 -2.43159157332545 0.00524425833641012 94.0911573881346 30.0149281739544 3.13481201230335 0.00188216051465721 -31.2104803582127 128.257487540876 -0.243342365086216 0.807899083809743 DLX5 other 1 1 1 3.13481201230335 -0.243342365086216 1.53252566967766e-12 938.788183797917 182.343785417182 5.14845176461637 4.60365050926572e-07 -1087.88306265825 406.607740085116 -2.675509970446 0.00784661512666101 MTPN other 2.01082693118406e-08 1 0.00557271894146615 5.14845176461637 -2.675509970446 0.000157726585724018 49.9025992101485 12.4345089471787 4.01323441256367 7.46411562099276e-05 -32.3212855070098 52.5954101326471 -0.614526731999896 0.539303998505899 STEAP1B other 1 1 0.784254628297709 4.01323441256367 -0.614526731999896 0.0788532109556649 -25.1122414498899 96.752066660276 -0.259552506904747 0.795376399943941 -456.786747050723 215.829415494017 -2.11642489048665 0.035082825586437 PTN other 1 1 1 -0.259552506904747 -2.11642489048665 3.34693992678975e-17 89.5883855898453 9.84993802474738 9.09532479948198 1.05017123785263e-17 -5.64488525219262 41.4952491702211 -0.136036904587228 0.891878182312495 MPP6 other 4.72822203457587e-13 1 1.53965605181575e-13 9.09532479948198 -0.136036904587228 0.585802896075157 25.329162466748 38.1923805278662 0.663199363764905 0.507680331193352 -33.6859220356561 84.0437681908512 -0.400814037266395 0.688824525952375 ATP6V0A4 other 1 1 1 0.663199363764905 -0.400814037266395 0.000307130263890328 52.2363070020539 62.0085677570862 0.842404669088401 0.400190640595569 -430.082441459267 136.452182932688 -3.15189125022225 0.00177566374068323 ZC3HAV1 other 1 1 1 0.842404669088401 -3.15189125022225 1.29412763091729e-08 17.5521307797828 8.62118206798418 2.0359308783148 0.0425805965367488 -80.9452986621951 18.9712350274718 -4.26673848829453 2.61562367360765e-05 TTC26 other 0.000149368211160473 0.380704025693594 1 2.0359308783148 -4.26673848829453 2.26295551521584e-12 817.922134422241 121.684071498375 6.72168612005366 8.24894511610356e-11 -1118.96773169203 487.987057220558 -2.29302747918226 0.0224946480916025 OGDH essential 2.9565513806295e-08 1 1.12235147249705e-06 6.72168612005366 -2.29302747918226 6.13090837266871e-06 97.2178516563852 19.5833561011183 4.96431005770423 1.13313042652386e-06 35.204832767832 94.1310115338355 0.373998241325364 0.708658036321299 ADAP1 other 0.0596230839242032 1 0.0134717876409422 4.96431005770423 0.373998241325364 0.341275105851749 -7.99389599948111 6.91474817960116 -1.15606465945694 0.24853635722251 -23.2377268349632 18.1177792251861 -1.28259244944655 0.200583911170013 TFEC other 1 1 1 -1.15606465945694 -1.28259244944655 0.00956634555663022 229.023291005157 87.1222684694269 2.62875720557628 0.00898325885008206 -370.942995674709 349.384589825653 -1.06170394023335 0.289170720380397 H2AFV other 1 1 1 2.62875720557628 -1.06170394023335 2.98038821729043e-07 795.558675662299 172.493483869744 4.61210857253629 5.8110764436154e-06 -509.439179626109 449.981527178688 -1.13213354072602 0.258442108106542 CAV2 other 0.00320093694536992 1 0.0662637046865464 4.61210857253629 -1.13213354072602 0.0191162289023188 1957.72872257778 839.222666647538 2.33278818647542 0.0202886779971657 -1172.42033591223 2179.96741123602 -0.537815533328307 0.591084165967072 CAV1 other 1 1 1 2.33278818647542 -0.537815533328307 3.75295914267415e-07 780.732386665013 157.173173980579 4.96733868059116 1.11350775015898e-06 -116.069339668831 406.590112412539 -0.28547014825354 0.775470995823513 MET other 0.00400590858889039 1 0.0132462881958913 4.96733868059116 -0.28547014825354 8.72613301435374e-05 -3.2315460189833 4.00137768873884 -0.807608346514727 0.419921660125421 -38.0402355068155 9.14176560769573 -4.16114754405783 4.08313522293228e-05 RNF32 other 0.756468471014326 0.590707172701613 1 -0.807608346514727 -4.16114754405783 3.48066948653812e-16 212.321871208697 35.2959360349384 6.01547642761269 4.94246965291277e-09 -229.337185336727 80.6390196665806 -2.84399768604543 0.00474461952165958 LMBR1 other 4.86353947353972e-12 1 6.44992289705117e-05 6.01547642761269 -2.84399768604543 0.0274471355646469 39.4812575016155 14.7670460070481 2.67360564074708 0.00789526363248731 53.5973899167832 38.066334750075 1.40799975276521 0.16011726788771 WNT2 other 1 1 1 2.67360564074708 1.40799975276521 4.50472360922366e-15 36.6715967393352 4.43498593462244 8.26870643558357 3.77092075736793e-15 -12.6046833968958 18.2593760564206 -0.690312930625229 0.49050251473872 HOXA1 other 6.1994006310136e-11 1 5.44143865288192e-11 8.26870643558357 -0.690312930625229 6.4222709326293e-10 435.831711839696 98.2637597277699 4.43532501755606 1.26943698852164e-05 -508.857989274496 221.046352576523 -2.30204200767501 0.0219806318111097 DNAJB6 other 7.8203993146627e-06 1 0.141427974891196 4.43532501755606 -2.30204200767501 0.0148716163409736 3.7120632715611 1.33438765618546 2.78184772944662 0.00572876109960295 -1.98083468677943 5.4938361425514 -0.360555836647051 0.718671641846873 HOXA2 other 1 1 1 2.78184772944662 -0.360555836647051 0.168424647377216 8.83812096064117 6.56007967642489 1.34725817315953 0.178859313008682 -28.5758644195588 27.0086452443555 -1.05802657486239 0.290848892186971 HOXA3 other 1 1 1 1.34725817315953 -1.05802657486239 0.0121219611249877 180.627871592101 68.0886354466514 2.65283435932015 0.00838380078223968 -269.829742659909 310.247455211261 -0.869724273729081 0.385109166627858 LFNG other 1 1 1 2.65283435932015 -0.869724273729081 0.146299860746252 7.85770951572144 3.99689569870286 1.96595310662511 0.0501764822399271 6.77054351878702 16.4314174278074 0.412048659133265 0.680582248160518 HOXA5 other 1 1 1 1.96595310662511 0.412048659133265 0.291365700002055 1.92016032147147 1.24217337632565 1.54580701701344 0.123148882040127 -0.0236028833008779 5.10663044590826 -0.0046220073198737 0.9963150921116 HOXA6 other 1 1 1 1.54580701701344 -0.0046220073198737 5.69497701177487e-11 300.513835306711 43.167640756032 6.96155337756602 1.94294811762087e-11 -47.3088856606084 196.694361756246 -0.240519785306485 0.810082799664496 BRAT1 essential 7.184213500354e-07 1 2.67369090465808e-07 6.96155337756602 -0.240519785306485 0.00163866104544484 77.8473872771758 24.2647532574002 3.20824969664318 0.00147197311001884 -116.344372596994 110.562914061274 -1.05229111935776 0.293467465233464 IQCE other 1 1 1 3.20824969664318 -1.05229111935776 0.0879711925525778 1.71342781778767 11.4258338543976 0.149960855340829 0.880890866088935 -57.7805342074282 29.8357303570733 -1.93662208083771 0.0536800306112358 TSPAN12 other 1 1 1 0.149960855340829 -1.93662208083771 3.96466272370524e-13 94.7282434596906 49.1448396234032 1.92753184638699 0.0548010423607633 -620.364465448363 107.347636212376 -5.77902306317242 1.78746952436721e-08 SSBP1 essential 5.2658650296253e-09 0.00027123062562748 1 1.92753184638699 -5.77902306317242 0.021474342047272 11.0169540371639 4.03265762699067 2.73193388980686 0.00664925067993151 17.3863274647614 16.5537819220462 1.05029337384265 0.294383274205107 HOXA13 other 1 1 1 2.73193388980686 1.05029337384265 0.329310785964264 37.3923312770687 25.5958644095989 1.46087393958244 0.145037369219943 22.75527771412 66.8425568910859 0.340430988467389 0.733756761942715 CPED1 other 1 1 1 1.46087393958244 0.340430988467389 1.55479346559893e-06 97.3069070176213 21.0947251959391 4.612854925285 5.77178413632703e-06 -145.936753912021 86.5923946188446 -1.68532992480914 0.0929090104462312 HIBADH other 0.0158588933491091 1 0.0658445134272188 4.612854925285 -1.68532992480914 9.47960102257405e-12 476.046360074671 70.2957483990423 6.77205052818182 6.17143485404118e-11 -501.696131208152 288.559207520215 -1.73862458079078 0.0830717078152565 TAX1BP1 other 1.21945587554393e-07 1 8.41475142348514e-07 6.77205052818182 -1.73862458079078 0.0315548672991435 34.0651732580618 23.8461508807965 1.42853970136936 0.154121120254011 -183.851689947401 96.5930121754284 -1.90336428905951 0.0578986099899708 CPVL other 1 1 1 1.42853970136936 -1.90336428905951 1.24199661112758e-19 364.540246471212 36.4447295164363 10.0025504732257 1.2984649690983e-20 82.8959428609691 220.77092485668 0.375483967894701 0.707555712549741 GRB10 other 1.79841109291274e-15 1 1.93263526000591e-16 10.0025504732257 0.375483967894701 0.0509348888421449 28.0967269053692 32.3873199144252 0.867522443339161 0.386312042543055 -222.032407703707 111.746711260992 -1.98692565712413 0.0477911386336425 ABHD11 essential 1 1 1 0.867522443339161 -1.98692565712413 0.983358531275281 1.41925759112668 19.8682561792267 0.0714334251745048 0.943098870424762 -19.6500878619696 122.900641634881 -0.159885966424382 0.873075029960684 COBL other 1 1 1 0.0714334251745048 -0.159885966424382 1.01732082786073e-10 147.770439571708 21.6976584425283 6.81043256179532 4.89230854218953e-11 -36.2368303011049 87.890167121488 -0.412296750454642 0.680400607814915 FKBP14 other 1.27165103482591e-06 1 6.68093654521402e-07 6.81043256179532 -0.412296750454642 6.02673457081167e-07 47.6312901043958 8.86844878484607 5.37087051636196 1.51891837858686e-07 0.102421001001729 35.9232056248395 0.00285110972754918 0.997726939997094 PLEKHA8 other 0.00633409803392307 1 0.00187844635879837 5.37087051636196 0.00285110972754918 1.06314813027703e-08 63.6767634747205 10.5344076850958 6.04464582900194 4.20370567349608e-09 3.10867513470469 36.3471079731937 0.0855274410552102 0.93189607270065 STX1A other 0.000123155079411291 1 5.49886739150022e-05 6.04464582900194 0.0855274410552102 1.48184805144031e-12 53.0072197591519 7.28890838535827 7.27231252702135 2.75152595621471e-12 -31.878185521669 29.6055474201467 -1.0767639276947 0.282399373416042 NOD1 other 1.94566649154113e-08 1 3.84030477708887e-08 7.27231252702135 -1.0767639276947 1.37459668349069e-10 564.771793600297 89.6788102380719 6.29771728796343 1.000073313946e-09 -630.230808047297 364.250739441153 -1.73021147194984 0.0845596454109452 GARS essential 1.71123541127756e-06 1 1.33109758086213e-05 6.29771728796343 -1.73021147194984 0.0139776398886345 36.7372899324436 67.9055395706996 0.541005787814921 0.588879994135149 -332.582491478848 148.030519557964 -2.24671569397971 0.0253396440141576 EPHB6 other 1 1 1 0.541005787814921 -2.24671569397971 1.16784886012202e-06 35.2176468523228 6.92773699608566 5.08357157210523 6.33511022094159e-07 -17.0205916720578 28.1228572480889 -0.605222702725715 0.545462689168345 MINDY4 other 0.0120370182012777 1 0.00762050408477064 5.08357157210523 -0.605222702725715 6.96983100008814e-09 -6.52778002830537 56.6822354550106 -0.11516447747525 0.90838698437241 -685.097771190095 123.564304431689 -5.54446346249488 6.17641208923857e-08 CASP2 other 8.14912640530306e-05 0.000934799969706257 1 -0.11516447747525 -5.54446346249488 9.30651717097916e-16 976.864069116435 113.858282187792 8.57964875585637 6.14449163113955e-16 1602.86682581635 723.93935626377 2.21408991229417 0.0276112651124772 CHCHD2 other 1.29351282159439e-11 1 8.91381400929414e-12 8.57964875585637 2.21408991229417 0.320103835841106 4.42671586366865 5.80706953636774 0.762297719348047 0.446445599998424 -21.1619076702599 20.1174626536366 -1.05191733344337 0.293633651337909 CCL24 other 1 1 1 0.762297719348047 -1.05191733344337 0.00564756136938271 533.842259407176 2206.82892599839 0.241904686456681 0.809009452869934 -23316.0740431712 7645.12947945628 -3.0497945268063 0.00248188391859957 HSPB1 other 1 1 1 0.241904686456681 -3.0497945268063 0.273952036233418 44.6534113190943 28.5111831514537 1.56617180991374 0.118306069158729 -7.00153516532921 124.663539172593 -0.0561634557449536 0.955246975502847 NPTX2 other 1 1 1 1.56617180991374 -0.0561634557449536 3.70410437351742e-19 668.724237893831 72.1554051864169 9.26783289714956 2.9598173653321e-18 -445.430266380826 315.468460867148 -1.41196449609081 0.158938189566476 PDAP1 essential 5.3383552231133e-15 1 4.35625919829579e-14 9.26783289714956 -1.41196449609081 0.000340281564224733 227.72096335212 58.9515116825625 3.86285197533753 0.000135816846494061 -101.344402076667 257.740118127569 -0.393203831878847 0.694432414186596 BUD31 essential 1 1 1 3.86285197533753 -0.393203831878847 1.25751209171006e-06 254.948144103665 49.210990355654 5.18071557310923 3.93308173466084e-07 -32.733123510066 215.153879950337 -0.152138197636137 0.879174415556199 PTCD1 other 0.0129322543511463 1 0.00477672776674559 5.18071557310923 -0.152138197636137 0.00733820643655904 59.0417079698506 19.0187801028214 3.10438985311639 0.00207758375636104 5.75658643981896 81.9070295685094 0.0702819583391677 0.944013280309616 CYP3A5 other 1 1 1 3.10438985311639 0.0702819583391677 1.84532278667031e-12 413.868993279562 59.2193151368786 6.9887500779594 1.63463649893243e-11 -419.102094089584 254.901758997145 -1.64417105530558 0.101129071893487 ZKSCAN1 other 2.41534299547277e-08 1 2.2522021682291e-07 6.9887500779594 -1.64417105530558 8.31743914526216e-17 1937.1938368359 218.900300599579 8.84966275299677 6.30058937783251e-17 -585.530715877315 997.424324345738 -0.587042747590295 0.557592852298815 EIF3B essential 1.16951511821531e-12 1 9.19697031482211e-13 8.84966275299677 -0.587042747590295 0.280264055619423 70.6947177222132 44.233355882527 1.59822189186733 0.11099299986555 59.3789479494763 201.325792479639 0.294939596254075 0.768233699985609 NUDT1 other 1 1 1 1.59822189186733 0.294939596254075 2.98167393837358e-05 496.028153195238 175.767735092772 2.82206602328595 0.00507283376136108 -988.665607782895 460.389110973989 -2.14745654103612 0.0325149033370346 PTPRZ1 other 0.272584631446113 1 1 2.82206602328595 -2.14745654103612 8.38938848493032e-28 404.962995728875 34.7957834920766 11.6382778338959 2.55529791691374e-26 -223.548391438017 150.455010412649 -1.48581553266253 0.138318609763887 TAF6 essential 1.26176402813352e-23 1 3.86028856308158e-22 11.6382778338959 -1.48581553266253 1.72568148850075e-18 420.645492839686 55.7151504960519 7.54993011944738 4.61289822497734e-13 -289.089172093597 135.395365927748 -2.13514820180675 0.0335104592475446 WASL other 2.47152102783077e-14 1 6.49772843970308e-09 7.54993011944738 -2.13514820180675 6.68127424967398e-17 195.426995324657 21.8953361693733 8.92550787130715 3.56279071390585e-17 -70.231705621419 105.148622071731 -0.667927969360437 0.504662520762734 AIMP2 other 9.40389350641613e-13 1 5.20773118651618e-13 8.92550787130715 -0.667927969360437 0.0120965197965692 21.5495557332288 7.23930827089373 2.97674238018992 0.00313617481116343 29.5262821023957 31.1599245806956 0.947572322453184 0.3440644718507 TFR2 other 1 1 1 2.97674238018992 0.947572322453184 1.50959583360598e-05 60.8474857231674 41.8472014608967 1.45403954383963 0.146921573166272 -332.262638687371 96.9863001821854 -3.42587188152581 0.000693291035211039 FSCN3 other 0.141841624525618 1 1 1.45403954383963 -3.42587188152581 9.54296985067674e-21 91.5073164476763 9.41982217421156 9.71433587124329 1.03474212799235e-19 -53.8468481088222 40.5454412947329 -1.32806171025242 0.185107147165533 MOSPD3 other 1.39241473091224e-16 1 1.53379825632306e-15 9.71433587124329 -1.32806171025242 0.260937502046931 121.848428849432 123.006030427633 0.990589066453279 0.322637050535072 -562.141106152065 529.450948581113 -1.06174350552881 0.289155289064274 PCOLCE other 1 1 1 0.990589066453279 -1.06174350552881 4.34132769983539e-19 183.732681046187 26.6856482164948 6.88507468717283 3.07621003449669e-11 -191.65421222717 61.3912831520712 -3.1218473110006 0.00196171180359001 RBM28 essential 6.25368255161287e-15 1 4.21963730431911e-07 6.88507468717283 -3.1218473110006 1.56883619759046e-19 99.0161956429011 10.3002913190104 9.61295099102251 2.22539181266709e-19 -57.6797264597987 49.3582586845371 -1.16859322020346 0.24344011385147 USP42 other 2.26916467619484e-15 1 3.29313480438475e-15 9.61295099102251 -1.16859322020346 1.69326646382881e-11 591.122116730942 101.88714009291 5.80173431300459 1.58163103418432e-08 -313.823703822247 234.394990755079 -1.33886693914105 0.181567295708161 IMPDH1 other 2.16585713388343e-07 1 0.000203207955272002 5.80173431300459 -1.33886693914105 2.81563317381872e-05 85.9337179003206 22.7395349203908 3.77904465509816 0.000187743237372941 -177.685982630668 97.5128531868278 -1.82218012111935 0.0693609214949988 AGFG2 other 0.258080936712224 1 1 3.77904465509816 -1.82218012111935 0.00010921295090604 115.912072384375 27.8311049059663 4.16483904523412 4.01173370956658e-05 -47.0782462157411 114.451473709579 -0.411338051751106 0.681100018553699 LSM5 essential 0.936719479921103 1 0.431448911315169 4.16483904523412 -0.411338051751106 5.18677454164071e-05 3428.49593677585 857.536621960669 3.99807524130799 7.93407478151724e-05 -3823.51394789199 3567.72492519851 -1.07169527585685 0.284664509641298 SERPINE1 other 0.462193479405603 1 0.830856311120485 3.99807524130799 -1.07169527585685 5.97103172359922e-10 241.799149946244 38.7628250980474 6.23791349920016 1.40288144098958e-09 -158.604078290218 161.270193869058 -0.983468020252988 0.326120129208477 AP1S1 other 7.2810760837569e-06 1 1.85923877374349e-05 6.23791349920016 -0.983468020252988 9.69510238377458e-12 113.557701247707 17.7024793943402 6.41479075998887 5.16371513322765e-10 -223.025425241365 82.6113484372838 -2.69969476906287 0.00731515495806062 C1GALT1 other 1.24688711757725e-07 1 6.91886190701172e-06 6.41479075998887 -2.69969476906287 9.08582038465504e-10 460.596829670505 78.5100836672784 5.86672193119154 1.10925421817457e-08 -546.214969104328 326.636058689534 -1.67224332578512 0.0954537631372081 PLOD3 other 1.10038370678557e-05 1 0.000143104886686701 5.86672193119154 -1.67224332578512 0.157692902036813 36.8196411595778 22.3127145381611 1.65016412936246 0.099906081921523 -76.0391961302159 103.801824192859 -0.73254200223821 0.464382534096693 RPA3 essential 1 1 1 1.65016412936246 -0.73254200223821 0.00147753451249727 229.787583926667 70.6731931514241 3.25141080627735 0.00127070336398771 -242.803889605751 294.031189214061 -0.825775967014794 0.409546404210134 ZNHIT1 other 1 1 1 3.25141080627735 -0.825775967014794 2.02611415197295e-05 22.4970154852451 5.23333267065687 4.29879331222055 2.28241544018147e-05 -19.2165131192586 21.7729376598153 -0.882587063789981 0.378121934883572 CLDN15 other 0.18802339330309 1 0.249741897464656 4.29879331222055 -0.882587063789981 0.125381926164553 23.5152562073764 12.9085131855693 1.82168588042073 0.0694419921131355 2.80634675707179 29.337529967203 0.0956572267743421 0.923853064544534 NOBOX other 1 1 1 1.82168588042073 0.0956572267743421 0.736879769232241 -6.55217384078619 9.59899959692649 -0.682589240120828 0.495366508605285 -21.473394768905 44.683257526024 -0.480569142847266 0.631155279439662 GLCCI1 other 1 1 1 -0.682589240120828 -0.480569142847266 1.37419415500633e-14 190.702312040123 24.0704627397457 7.92266912780328 3.91357856859125e-14 -144.339639685012 102.350881925785 -1.41024324333301 0.159442176301641 PHF14 other 1.87604986041464e-10 1 5.59485192165805e-10 7.92266912780328 -1.41024324333301 0.0121249039738545 16.2009086442589 9.92204578391463 1.63281937990282 0.103490530446301 -34.5794664894077 22.9702576368635 -1.5054017693695 0.133207222102922 NRF1 essential 1 1 1 1.63281937990282 -1.5054017693695 2.20783814674298e-08 254.087474614809 43.8061575837798 5.80026846976623 1.59418719349909e-08 -171.172386534097 188.813703329022 -0.906567603495477 0.365319762856039 TMEM106B other 0.000252179273120984 1 0.000204789286876894 5.80026846976623 -0.906567603495477 0.000234332657973143 -25.6871626199272 51.6666964330005 -0.497170602986731 0.619414482406771 -438.215153369481 115.686379143265 -3.78795806917596 0.00018181236214299 EZH2 other 1 1 1 -0.497170602986731 -3.78795806917596 6.47093190545176e-07 31.800840669345 10.1652716361867 3.1283808055005 0.00191938195461947 -60.9947430421084 23.5333431750992 -2.59184352126592 0.00998398357026664 CEP41 other 0.00678865466200944 1 1 3.1283808055005 -2.59184352126592 0.00581106884381628 0.555969304383607 15.6555783226781 0.0355125369963656 0.971693471665912 -96.8383703636465 35.0392353971223 -2.76371242882771 0.00605000627197351 ZNF862 other 1 1 1 0.0355125369963656 -2.76371242882771 0.618095889878657 144.460483531786 155.066789231111 0.931601694006075 0.352244717290757 293.9611446104 633.173335887311 0.464266462197829 0.642772537970272 SFRP4 other 1 1 1 0.931601694006075 0.464266462197829 0.000140594693192042 318.785731279444 88.320269237288 3.60942888911457 0.000356029923215336 -85.4176094332527 204.467846966258 -0.41775570438392 0.676405908897016 MEST other 1 1 1 3.60942888911457 -0.41775570438392 0.564225952674797 -0.361990022551766 2.39795767675572 -0.150957636183769 0.880104547416382 -10.9181896431094 10.2040093527933 -1.06999016422114 0.285432664341971 MEOX2 other 1 1 1 -0.150957636183769 -1.06999016422114 0.00222442434670026 26.9722089341443 10.010389141596 2.6944216206408 0.00742441513514893 -74.8512006456379 42.5971256357386 -1.75718900110102 0.0798448685106888 ANKMY2 other 1 1 1 2.6944216206408 -1.75718900110102 3.9536422724996e-06 6.15467563404155 4.56073483503806 1.34949210086891 0.178135892634922 -36.0021939053252 10.1502036247735 -3.54694302067546 0.000448179880030248 ACTR3C other 0.0390698929368411 1 1 1.34949210086891 -3.54694302067546 0.0420709416069347 15.8904889934466 6.30963269286099 2.51844913435703 0.0122746624156252 5.52166862712163 26.3567130123237 0.209497619241817 0.834193102083705 POU6F2 other 1 1 1 2.51844913435703 0.209497619241817 0.0254569246082901 126.158705209686 60.8974670931954 2.07165767693781 0.0391008120956916 -354.786705196669 259.136485103066 -1.3691113586555 0.171927654286835 TSPAN13 other 1 1 1 2.07165767693781 -1.3691113586555 0.313205418944651 103.934426071278 74.989301589276 1.3859900528283 0.166718016890726 209.167932690637 166.893430190916 1.25330237656067 0.211013500485474 RARRES2 other 1 1 1 1.3859900528283 1.25330237656067 0.558724935617539 -140.959042347206 135.835988432977 -1.03771499713242 0.300188699882068 62.1997124893831 578.021751531199 0.107607909779544 0.91437436907897 AGR2 other 1 1 1 -1.03771499713242 0.107607909779544 5.66715299129908e-05 543.748263058382 130.419777463424 4.16921630778641 3.94240064400485e-05 -495.088914326067 554.974194051039 -0.892093577743069 0.37301519542316 AHR other 0.502449784208576 1 0.424360005320682 4.16921630778641 -0.892093577743069 0.000255247129453437 250.348087591241 80.4687118906005 3.11112333861634 0.00203216340885623 -162.697518248176 177.007566723615 -0.919155724581065 0.35870860961955 CHCHD3 other 1 1 1 3.11112333861634 -0.919155724581065 0.00795439608776925 -12.0666181837745 7.92550139933386 -1.52250533761671 0.128870066160747 -55.2563590564857 17.6420261604907 -3.13208690168663 0.00189603623312872 GIMAP2 other 1 1 1 -1.52250533761671 -3.13208690168663 0.0609162738613588 -133.029338074025 62.9148866653079 -2.11443340558983 0.0352513043419642 -280.924615987634 140.04742671889 -2.00592486823424 0.0457056299641532 TMEM176B other 1 1 1 -2.11443340558983 -2.00592486823424 9.06607283387321e-12 286.058203156704 40.9339501381432 6.98828728210494 1.62285438177406e-11 -190.923518981983 166.347165071001 -1.1477413450388 0.251932681184949 GLI3 other 1.16734753808951e-07 1 2.23629333808465e-07 6.98828728210494 -1.1477413450388 2.5650090326861e-05 318.595260104534 75.6930838577497 4.20904056047276 3.33579580748976e-05 -372.958343124817 307.810798219925 -1.21164801651417 0.226541090157519 PSMA2 other 0.235878230645813 1 0.361099896160767 4.20904056047276 -1.21164801651417 5.16763223095951e-05 107.904838895774 26.1116012143432 4.13244817925994 4.58796403258973e-05 -101.758121696427 102.690566571815 -0.990919858498045 0.322473394268797 MRPL32 essential 0.460591060745421 1 0.491279188609708 4.13244817925994 -0.990919858498045 0.00403112527900644 70.2698628421872 25.8924810964121 2.71390997952391 0.00701086347615022 -146.718141907447 103.673859632321 -1.41518934886559 0.157988445857532 COA1 other 1 1 1 2.71390997952391 -1.41518934886559 0.00110944988148158 128.040195526595 37.0423101828411 3.45659314698754 0.000620942214233905 -106.468610392395 148.549992749192 -0.716719054790892 0.474070231685258 BLVRA other 1 1 1 3.45659314698754 -0.716719054790892 4.97892853253839e-20 215.300153271024 23.3305216405419 9.22826144173703 3.85832115015533e-18 -218.427141237472 93.5618972853045 -2.33457366273161 0.0201839443437458 URGCP other 7.22840844353923e-16 1 5.67366125130341e-14 9.22826144173703 -2.33457366273161 3.49333440511843e-16 441.224296204924 56.8684303022499 7.75868603827927 1.31144656330266e-13 -556.59521628768 215.180584607429 -2.58664236507732 0.0101561691462287 TMEM248 other 4.88088683083147e-12 1 1.86264755385877e-09 7.75868603827927 -2.58664236507732 0.0344298790269126 14.5652658981034 6.66217892327943 2.18626159186576 0.0295513296503198 -21.9271104499813 24.8007610883549 -0.884130546311222 0.377317616593034 STAG3L4 other 1 1 1 2.18626159186576 -0.884130546311222 1.05603968164936e-14 157.758520813494 33.4741651915801 4.71284406677828 3.65391098650618e-06 -268.981480843103 74.3968415293987 -3.61549597151664 0.000348274514855587 RHEB other 1.44603513608246e-10 1 0.0421990179831599 4.71284406677828 -3.61549597151664 5.01262557359367e-06 51.5842816863375 17.362554699647 2.97100758377373 0.00319370388863274 -76.3139071186207 38.5885420336059 -1.97763126298373 0.0488307329374675 PRKAG2 other 0.0491387684979388 1 1 2.97100758377373 -1.97763126298373 1.22145271869476e-07 564.066255039773 98.9988654987205 5.69770423325774 2.75511886299442e-08 37.2604501146947 397.013055595693 0.0938519516915831 0.925285497422488 POLD2 essential 0.00134103293985497 1 0.00035072663125919 5.69770423325774 0.0938519516915831 0.373693571862764 -8.45789918962389 6.06154320242444 -1.39533760746619 0.163881614344461 -10.4073443989587 24.3084784486841 -0.428136397797536 0.668839827611035 GCK other 1 1 1 -1.39533760746619 -0.428136397797536 4.93632562960062e-12 165.155775448221 28.2138619580738 5.85371033903991 1.20342164993953e-08 -288.861413566754 95.560559797383 -3.02280997703683 0.00270932971153105 BCL7B other 6.40192070902904e-08 1 0.000155072913811208 5.85371033903991 -3.02280997703683 1.55787861869928e-18 931.298491019831 101.379194326228 9.18628814530727 5.25540013044764e-18 -494.911398572299 406.558837927345 -1.21731801747413 0.224380183423409 YKT6 essential 2.23181690914858e-14 1 7.72070833164063e-14 9.18628814530727 -1.21731801747413 8.38169458065393e-20 267.915082786322 28.2588994116012 9.48073309169055 6.2724769960146e-19 -73.3789953142367 95.7131019866559 -0.766655701164789 0.443858606611586 TBL2 other 1.21459136168256e-15 1 9.26319402771437e-15 9.48073309169055 -0.766655701164789 0.00536312541370145 109.658860170374 47.1358278046131 2.32644392339794 0.0206249293517297 -251.311473703641 160.741537787467 -1.56345072445385 0.118944329611968 CLIP2 other 1 1 1 2.32644392339794 -1.56345072445385 9.76370783226248e-18 1352.00105438659 163.180081202341 8.28533142295794 3.36211637706074e-15 -1225.47055130282 563.023969437543 -2.17658682014384 0.0302491624993732 EIF4H other 1.38869216498269e-13 1 4.85220635537406e-11 8.28533142295794 -2.17658682014384 5.9742681353051e-14 440.335238223318 58.5256157803096 7.52380359185328 5.54015187222457e-13 -235.838588523512 201.932271804346 -1.16790935107202 0.243720979327725 LIMK1 other 8.06227484859424e-10 1 7.79720974496886e-09 7.52380359185328 -1.16790935107202 8.60010561682096e-27 16.666517179467 1.49408667570117 11.1549868227327 1.45292641815756e-24 -13.4655081093715 5.03004208991505 -2.67701698488152 0.00781838048852344 SPATA6L other 1.28975783935464e-22 1 2.18709013725257e-20 11.1549868227327 -2.67701698488152 1.59066261710528e-06 -11.4439389559082 9.96052218692023 -1.14892961846277 0.251462226600931 -176.94818603453 33.5517084167482 -5.27389496345891 2.49650871105537e-07 SLC1A1 other 0.0162088520683028 0.00376373653278707 1 -1.14892961846277 -5.27389496345891 0.0456231512851653 16.1975712123475 14.3648642426948 1.12758261677166 0.260343628038475 -58.3813453957109 28.2454049973866 -2.06693249401496 0.0395469703032612 LHX2 other 1 1 1 1.12758261677166 -2.06693249401496 2.99658231047714e-07 75.5598067752527 14.8274900945633 5.09592697707871 5.94562417105632e-07 -53.7671270204991 29.6165914755243 -1.81543939872126 0.0703923173016824 FKTN other 0.0032180297432214 1 0.00716209887645445 5.09592697707871 -1.81543939872126 0.0023028142820588 18.0278692017093 5.64136503013984 3.19565727539217 0.00153426447120956 20.2034832476621 11.2681244361931 1.79297658293236 0.0739209642319811 FSD1L other 1 1 1 3.19565727539217 1.79297658293236 0.00142238858503251 23.425873480637 8.14245647125955 2.87700321927706 0.00429598919901095 -26.8138727248917 20.8665733220302 -1.2850156233646 0.199755461334978 CNTNAP3 other 1 1 1 2.87700321927706 -1.2850156233646 3.45819857517843e-09 354.816508704082 63.4422721289245 5.5927459215685 4.80883795252026e-08 -271.293077718371 121.2930153123 -2.23667518710667 0.0259983358426956 SPIN1 other 4.09796531158644e-05 1 0.00060634637743328 5.5927459215685 -2.23667518710667 0.000321498731223021 63.0272471939058 20.8011224030014 3.02999261159155 0.00264493865685441 -82.6780249065446 40.052035799982 -2.06426523034771 0.0397981983188584 NMRK1 other 1 1 1 3.02999261159155 -2.06426523034771 2.88028877212415e-07 269.846581594033 48.0414969988629 5.61694781493632 4.24429922467695e-08 69.9913687569999 96.3929277520894 0.726104812761876 0.468308595331247 TMEM245 other 0.00309688648778788 1 0.000536139878061193 5.61694781493632 0.726104812761876 0.234038324068951 28.0289699154213 48.0077667923696 0.583842402764635 0.559737653371421 156.616530016631 92.742125257519 1.68873130286534 0.0922450768261475 PRUNE2 other 1 1 1 0.583842402764635 1.68873130286534 0.0382199620815977 109.505781128087 43.9778082184374 2.49002361791594 0.0132838054247833 80.5143696358005 87.9815653639795 0.915127723662484 0.360817976114431 MEGF9 other 1 1 1 2.49002361791594 0.915127723662484 4.64727489177139e-13 356.721846652592 66.214465148006 5.38737035563496 1.38833997157702e-07 -635.712397166158 125.94062231449 -5.04771522867896 7.51693443486727e-07 TRIM14 other 6.16321596146722e-09 0.0112746499588574 0.00171876488481235 5.38737035563496 -5.04771522867896 0.0284909800657625 67.8891337720678 82.2828564046412 0.825070211931029 0.40994635148746 -380.52492551744 156.502874685327 -2.43142451078003 0.0155881386479317 CORO2A other 1 1 1 0.825070211931029 -2.43142451078003 2.40703249070823e-08 492.678707459054 81.6007586350996 6.03767312583702 4.33076794009755e-09 -4.53698987986022 156.212035863151 -0.0290437920150714 0.976847769228646 TGFBR1 ts 0.000274500918472796 1 5.66074677450151e-05 6.03767312583702 -0.0290437920150714 1.95182651641089e-07 248.139929000751 54.3104356190616 4.56891803890558 7.00835148645754e-06 -291.27323969018 103.968931889549 -2.80154113730449 0.00539556450813853 SEC61B essential 0.00211851250091238 1 0.0795517977227795 4.56891803890558 -2.80154113730449 0.0040896031433093 3.03755515747264 10.4413128120051 0.290916976836492 0.771305061169305 -68.5519867345534 20.9160050249781 -3.2774894944177 0.00116355270797416 C5 other 1 1 1 0.290916976836492 -3.2774894944177 0.840424621377541 10.0525236611363 18.0582709714712 0.556671437537821 0.578141024428472 9.27538015034149 34.463227405762 0.269138465795305 0.787996578200702 OGN other 1 1 1 0.556671437537821 0.269138465795305 0.208242924450708 0.653857482235322 109.882495707579 0.00595051539396573 0.995255911505996 369.077127540529 209.704763178357 1.75998447506232 0.0793658377728112 ASPN other 1 1 1 0.00595051539396573 1.75998447506232 0.904202204881959 7.71600502427869 21.6641080251755 0.356165368789337 0.721951426372815 13.1988148847295 41.3447711906714 0.319237826322946 0.749754469378968 ECM2 other 1 1 1 0.356165368789337 0.319237826322946 1.89549633139741e-05 139.024978426947 39.731169155229 3.49914138906355 0.000532903861906577 -189.592587807609 76.4821966244609 -2.47891138297893 0.0136933259514019 TLE4 other 0.176375933636529 1 1 3.49914138906355 -2.47891138297893 0.25489808552404 10.277086626519 8.85130597331371 1.16108138815944 0.246474186369236 -18.1447747682896 17.6981531527274 -1.02523549274933 0.306026461075363 LHX6 other 1 1 1 1.16108138815944 -1.02523549274933 0.0108179348020022 383.639355599758 145.871639875591 2.62997904134725 0.00895173090633192 506.555866193848 291.286719437215 1.73902836069062 0.0829914454163874 PTGR1 other 1 1 1 2.62997904134725 1.73902836069062 0.00107445060929834 31.4867602140753 9.17528439218163 3.43169310816192 0.000678589410977683 -21.3769092635302 18.3621500848436 -1.16418334262364 0.245216946481591 SUSD1 other 1 1 1 3.43169310816192 -1.16418334262364 8.67672252096513e-06 -72.3990542648402 42.6944776171954 -1.69574751362413 0.090906333209763 -407.204081640131 85.6688138992467 -4.75323589887722 3.03005004272795e-06 AKNA other 0.0832705060337023 0.0450780544856637 1 -1.69574751362413 -4.75323589887722 0.0571938104697111 -1.97708202322469 1.88401628999101 -1.049397520461 0.294789569180414 -8.51984311252683 3.79515223993219 -2.24492789060791 0.0254576266709825 TNFSF8 other 1 1 1 -1.049397520461 -2.24492789060791 0.0296930750325374 93.8079857886772 37.8262023507366 2.47997366795799 0.0136533840367782 92.7130126518604 73.660468537156 1.25865358302865 0.209072959769644 DNM1 other 1 1 1 2.47997366795799 1.25865358302865 0.657562297590612 -50.2526696014369 85.0414018120241 -0.590920052241326 0.554991124098539 103.839497509742 166.509845697322 0.62362376876199 0.533318957975902 ENG other 1 1 1 -0.590920052241326 0.62362376876199 0.0115446187250956 228.601916041892 76.1241127425541 3.00301583566572 0.0028838780899363 28.287156635571 149.049921526764 0.189783103176553 0.849599422813667 AK1 other 1 1 1 3.00301583566572 0.189783103176553 8.70795271408004e-53 144.697605062046 8.00164912683736 18.0834728901988 1.37385020237728e-50 -69.7761042011528 26.9320591872204 -2.59081950310961 0.0100215681438784 CDC37L1 other 1.33527746917703e-48 1 2.10624974526461e-46 18.0834728901988 -2.59081950310961 8.03843037781815e-36 136.904122382809 11.1497433530019 12.2786792528233 1.48565214078367e-28 -210.161633537404 37.5392084161323 -5.59845671777906 4.73192088761211e-08 PLGRKT other 1.22369025641526e-31 0.000716554780011102 2.25210008021397e-24 12.2786792528233 -5.59845671777906 1.93303430740664e-14 184.035193132162 23.4873759241053 7.8354940001316 6.96438571577426e-14 -88.3295119337366 45.8790605662453 -1.92526853958129 0.055081822686959 TBC1D13 other 2.63182620953415e-10 1 9.92773183783621e-10 7.8354940001316 -1.92526853958129 7.56490537455846e-37 315.388654550887 22.6123929297188 13.9476018982662 1.01635166486e-34 -194.827186619944 76.1319165922906 -2.55907371494799 0.0109651202066166 RIC1 other 1.15289157908271e-32 1 1.54973301857853e-30 13.9476018982662 -2.55907371494799 2.79792223036763e-35 106.74735422618 8.29940391333763 12.8620507377199 1.06016966752786e-30 -116.774068597248 27.9273190397668 -4.18135619931756 3.76290349740202e-05 KDM4C other 4.25703867350435e-31 0.545207087738578 1.61188196250936e-26 12.8620507377199 -4.18135619931756 3.69507678964497e-09 49.9681742424239 22.4759412016378 2.22318495115047 0.0269171644268915 -386.991361742424 70.2718592854269 -5.50706023261119 7.61700261726328e-08 DOCK8 other 4.37423190358171e-05 0.00115222398591342 1 2.22318495115047 -5.50706023261119 9.4571998665042e-19 733.346491979084 79.8990306056992 9.17841538776785 6.02694871831935e-18 -404.311978555626 253.959525031608 -1.59203313404097 0.112383427935243 KANK1 other 1.35767561283534e-14 1 8.84816341336464e-14 9.17841538776785 -1.59203313404097 0.00729946491391994 32.4506500586945 11.1307384239988 2.91540855804572 0.00381899431598433 -10.8984818047418 25.1463574894864 -0.433402007002342 0.665033171199323 ELAVL2 other 1 1 1 2.91540855804572 -0.433402007002342 8.19951700239329e-14 565.806720976664 72.58001565366 7.79562687994725 9.15212474856953e-14 -228.232473680622 147.182581732658 -1.55067584080827 0.121970889527383 NCS1 other 1.10414695954228e-09 1 1.30317104294882e-09 7.79562687994725 -1.55067584080827 1.16031579495485e-41 305.449040730532 19.5411179577266 15.6310934405755 5.89880305314724e-41 -39.7579991393988 61.5505464878555 -0.645940635916912 0.518798762616269 TESK1 other 1.77354269258849e-37 1 9.02162938948339e-37 15.6310934405755 -0.645940635916912 1.71631785455554e-08 477.660040919319 77.7861461715206 6.14068268488409 2.53066739149695e-09 203.082035772921 244.992161685364 0.828932788607882 0.407784363583929 CA9 other 0.000197187758309885 1 3.33162362090573e-05 6.14068268488409 0.828932788607882 1.24336592606546e-06 200.321138192778 38.4304502475778 5.21256287402992 3.35302594774169e-07 -44.1034380969838 77.931822329412 -0.565923351703003 0.571843754531092 FUBP3 other 0.0127929920132875 1 0.00408331499915983 5.21256287402992 -0.565923351703003 0.543439669401666 3.48877273661308 4.70017241419496 0.742264842471876 0.458480003844071 16.1405580024135 17.6070703028847 0.916708897321155 0.359996492924198 TYRP1 other 1 1 1 0.742264842471876 0.916708897321155 2.15556973332796e-34 270.747004363333 21.072544664414 12.8483298374759 1.51460679140977e-30 -214.255083665879 66.3692511281182 -3.22822813311973 0.00137991427862022 CREB3 other 3.27603488071183e-30 1 2.30220232294286e-26 12.8483298374759 -3.22822813311973 7.17516982695129e-49 382.479156197852 23.7908746763021 16.0767168673642 1.09955498125193e-42 -336.628631449211 76.2994406528774 -4.41194101252584 1.41681966206145e-05 RGP1 essential 1.09930776918721e-44 0.207847444424415 1.68242907681358e-38 16.0767168673642 -4.41194101252584 0.00966839869590075 28.1733017307526 9.18111643546764 3.06861392389232 0.00233860976548818 15.4531694495683 34.40168562154 0.449198031153817 0.653599675928206 MPDZ other 1 1 1 3.06861392389232 0.449198031153817 2.79490434345104e-13 653.481358543615 91.6923593352637 7.12688999695414 7.28016210523731e-12 -285.824514533453 228.574894275542 -1.25046329098986 0.212076446410799 DDX58 other 3.72448952808285e-09 1 1.00924887264905e-07 7.12688999695414 -1.25046329098986 5.53453521368846e-07 1507.32886971047 311.836089048178 4.83372169754729 2.08649922011734e-06 -1279.59094086632 650.618894492962 -1.96672883572422 0.050081026489677 EDF1 other 0.00583284666170626 1 0.0244287328691338 4.83372169754729 -1.96672883572422 0.548652043462881 -16.2558106869956 18.0796022197279 -0.89912435513973 0.369266741443784 -27.5046357621271 35.1469987831318 -0.782560011221428 0.434467876042245 PIP5K1B other 1 1 1 -0.89912435513973 -0.782560011221428 0.391062363867297 -1.09031239723058 8.90718229828585 -0.122408227508761 0.902653779696674 39.7087408718986 29.8520463171978 1.3301848874937 0.184419619829332 GLIS3 other 1 1 1 -0.122408227508761 1.3301848874937 4.41944219789448e-16 525.407222647475 84.1837733821605 6.24119354049785 1.42514114234835e-09 -908.202106553653 215.128397029637 -4.22167467937083 3.18978697548122e-05 BAG1 other 6.16865741982111e-12 0.463125170970119 1.8880269853831e-05 6.24119354049785 -4.22167467937083 2.12226691587582e-06 418.383639264156 80.2938350984233 5.21065706665158 3.38492016725803e-07 46.0695436753518 166.122292823204 0.277323066593967 0.781711676719296 RAPGEF1 other 0.0213882059781965 1 0.0041218172876701 5.21065706665158 0.277323066593967 0.000608842507068486 250.763040649765 65.8083738951646 3.81050352420561 0.000166389718097943 177.439938457238 138.463579347035 1.28149177779462 0.200951685711516 NPDC1 other 1 1 1 3.81050352420561 1.28149177779462 0.242592221509862 6.95210235459515 9.27298854284185 0.749715404313933 0.453978665844233 -24.2304657579002 18.0006949092696 -1.34608501949681 0.179230889480726 APBA1 other 1 1 1 0.749715404313933 -1.34608501949681 4.16794006389499e-06 345.482606397162 73.8991553173316 4.67505487598092 4.33827920655458e-06 -224.03802003365 152.864857757132 -1.4655953194265 0.143740440354221 SETX other 0.0411042249101324 1 0.0498511663625187 4.67505487598092 -1.4655953194265 0.0235677018657505 -45.7497338642905 48.1218064687168 -0.950706908603518 0.342472913135017 -271.906606079723 101.250299527511 -2.68548939952364 0.00762120624335376 PTGDS other 1 1 1 -0.950706908603518 -2.68548939952364 0.0377830841631845 -5.69506761818408 60.7475199866215 -0.093749796196426 0.925366767286479 -327.443341768432 127.815330419845 -2.56184716413011 0.0108708895729989 ABCA2 other 1 1 1 -0.093749796196426 -2.56184716413011 2.66558573926976e-18 249.765328323106 32.7537261623186 7.6255546341609 2.97695259435699e-13 -368.059793575542 96.6849274706265 -3.80679598365899 0.000169558944198666 SHB other 3.81258728287754e-14 1 4.206136320567e-09 7.6255546341609 -3.80679598365899 7.42258221986561e-62 635.623678942808 31.4824418450541 20.1897833106826 8.36603515208158e-59 -232.211408461999 105.126121091059 -2.20888401523786 0.0278999619316174 UBE2R2 other 1.13929214492717e-57 1 1.28385175443844e-54 20.1897833106826 -2.20888401523786 0.00198339657734812 43.8218650026875 16.1669881034498 2.71057693135412 0.00707893550078101 -54.1905644077085 31.1291272534324 -1.74083147164793 0.0826742793219956 ABHD17B other 1 1 1 2.71057693135412 -1.74083147164793 3.57074866618188e-44 193.017622672128 12.5271174636425 15.4079837785766 3.38119375911296e-40 -96.8422710351476 37.1280271329707 -2.60833334042543 0.00953770043958483 EXOSC3 essential 5.46395960899151e-40 1 5.16849278018006e-36 15.4079837785766 -2.60833334042543 0.00120704067980579 378.30285699101 108.122149708636 3.49884698010951 0.000533470713528448 -107.16927377513 208.186468355018 -0.514775406019068 0.607065342827725 ZFAND5 other 1 1 1 3.49884698010951 -0.514775406019068 8.60510492330632e-06 104.334577570049 394.448926305039 0.264507191203161 0.791560475256211 -3057.63307828533 722.710863567281 -4.23078333594286 3.04957041796752e-05 PDLIM1 other 0.0826004021588174 0.44313307743486 1 0.264507191203161 -4.23078333594286 0.00105434648218613 35.2052047608916 10.129825136355 3.47540103476646 0.00058046988789083 6.91264214157436 18.5525837717184 0.372597274138819 0.70969485782591 CCNJ other 1 1 1 3.47540103476646 0.372597274138819 0.433206927517046 -9.83274477374812 21.2411797128338 -0.46290954206311 0.643745823876782 -55.1197779615426 42.9953479544721 -1.28199399665073 0.200778595884029 GATA3 other 1 1 1 -0.46290954206311 -1.28199399665073 0.459381979040803 -12.0802164320235 9.81791885442739 -1.23042536928037 0.219441564455162 -6.23992675005436 18.9380229825841 -0.329491983180756 0.741999416424332 ATRNL1 other 1 1 1 -1.23042536928037 -0.329491983180756 1.36724652120607e-05 23.5937024621585 49.3321254412486 0.478262435504773 0.632790001157395 -361.867317368649 90.102765371819 -4.01616216633711 7.37645172340388e-05 HPS1 other 0.12898603681058 1 1 0.478262435504773 -4.01616216633711 0.0402328291524602 93.9328572421249 38.17801433132 2.46039137674757 0.014411565693863 52.0128754782898 78.1007188461248 0.665971789334824 0.505913459861738 PHYH other 1 1 1 2.46039137674757 0.665971789334824 0.0115132815744981 -75.2971818183419 40.9351804654511 -1.8394246944115 0.0667997048016672 -257.108916079912 88.2483386575224 -2.91347032693398 0.00383167127543923 RASSF4 other 1 1 1 -1.8394246944115 -2.91347032693398 0.000537846556848232 131.534607556823 55.0050367904941 2.39131932695215 0.017365243262685 -167.40724387167 100.600902168212 -1.66407298805087 0.0970767244240195 DNMBP other 1 1 1 2.39131932695215 -1.66407298805087 0.0216641027480797 27.0139904007947 12.624694228021 2.13977383633072 0.033129088795661 -17.2245021981649 24.549431802094 -0.701625289620579 0.483422828837396 RAB11FIP2 other 1 1 1 2.13977383633072 -0.701625289620579 0.22934923925434 -134.483651012456 120.255105821193 -1.1183196762757 0.264299141295549 -407.804266100457 246.903857414363 -1.65167231638696 0.099617188789606 CXCL12 other 1 1 1 -1.1183196762757 -1.65167231638696 1.78250009144082e-06 86.1137557240734 68.3705957171198 1.25951448602796 0.208762439559838 -493.742827918844 125.045705125481 -3.94849889025284 9.67506034776744e-05 ERLIN1 other 0.0180656384267527 1 1 1.25951448602796 -3.94849889025284 5.45688409591109e-08 1292.38682944829 309.894473730447 4.17040941030924 3.91986556401683e-05 -1230.09271191096 603.257142417159 -2.03908520168062 0.0422628853853666 EIF3A essential 0.000610461623809574 1 0.422051925277693 4.17040941030924 -2.03908520168062 0.845884839105845 -1.423849639148 2.50912116480825 -0.567469462662165 0.570793155856514 -0.957121858469922 4.9868467628672 -0.191929269934018 0.847919342425081 CUBN other 1 1 1 -0.567469462662165 -0.191929269934018 0.0245489765671742 6.24685493104011 4.77903970113636 1.3071360193042 0.192104993962149 -13.322590818856 9.49828130960228 -1.40263173774265 0.161696098062739 TRDMT1 other 1 1 1 1.3071360193042 -1.40263173774265 5.10933672132535e-12 142.708588858719 26.0338318615907 5.48165900499902 8.55661853723248e-08 -140.259525099459 54.5306637987022 -2.57212209294245 0.0105585394470156 DDX50 other 6.62272225818192e-08 1 0.0010682082581881 5.48165900499902 -2.57212209294245 0.00661992224083515 -3.47180280607015 28.915748227051 -0.120066158371868 0.904506086843737 -179.834399744328 60.4448561667186 -2.97518120066842 0.00315102904343152 MAPK8 other 1 1 1 -0.120066158371868 -2.97518120066842 5.3479071511966e-07 146.944190331328 42.4922021691996 3.45814485552458 0.000617505805260072 -198.541020978553 83.398490765681 -2.38063086221044 0.0178680154425986 SEC23IP other 0.00564257683522754 1 1 3.45814485552458 -2.38063086221044 0.00268857057648393 67.8864478518829 30.7719763771331 2.20611269877127 0.0280863158798302 -90.6189545012052 61.3083586711673 -1.47808482342918 0.140368651508871 ATE1 other 1 1 1 2.20611269877127 -1.47808482342918 0.0421056520163647 -19.7938872994754 26.6711460872103 -0.742146109310511 0.458543192921898 -133.001818024659 53.1380945586872 -2.50294669256098 0.0128145266874446 NSMCE4A other 1 1 1 -0.742146109310511 -2.50294669256098 0.0120705361384934 287.709940754785 122.79398582072 2.3430295778072 0.0197399981469421 -166.041198167522 244.647845594775 -0.678694708158378 0.497821852588363 PLEKHA1 other 1 1 1 2.3430295778072 -0.678694708158378 0.305510082234014 9.86757484372647 21.6330014646847 0.456135264440074 0.648602119794396 -60.4257224398305 49.9048054651411 -1.21081971719213 0.226858009586378 PALD1 other 1 1 1 0.456135264440074 -1.21081971719213 0.000109300022230404 343.921528186996 119.729607013221 2.87248523374021 0.00434453052409126 -550.207032017286 276.202206899803 -1.99204430041677 0.0472156728656976 UNC5B other 0.937356990647948 1 1 2.87248523374021 -1.99204430041677 0.701061293560606 -8.4330742576609 23.5997798099113 -0.357336988971364 0.721075091478806 -45.7992330435743 54.4419331897342 -0.841249205533547 0.400836533480416 CDH23 other 1 1 1 -0.357336988971364 -0.841249205533547 5.50378484709329e-06 -79.1177240882612 102.415934298431 -0.772513814673793 0.440380350789627 -1158.14037844563 236.261587927939 -4.90194105864921 1.5112226314868e-06 VSIR other 0.0537554666015602 0.0225867334502017 1 -0.772513814673793 -4.90194105864921 0.188765735903664 -373.605188707274 204.541186087929 -1.82655237242375 0.0687015367486461 -367.762649434655 474.125490083958 -0.775665213379545 0.438521336865291 SPOCK2 other 1 1 1 -1.82655237242375 -0.775665213379545 4.84387250166125e-15 159.812420117187 28.7027868783796 5.56783634963217 5.49118263451205e-08 -265.163899484239 66.6426271629416 -3.97889325155071 8.58023968024501e-05 MICU1 other 6.66371540053538e-11 1 0.000690790775421615 5.56783634963217 -3.97889325155071 2.77626583349908e-09 145.937614581752 34.4099019727284 4.24115170968564 2.91446163068143e-05 -241.596270359989 81.1390801512616 -2.97755742250959 0.00312736734455949 PPP3CB other 3.30209058236381e-05 1 0.316685400789844 4.24115170968564 -2.97755742250959 5.10165581231537e-06 137.569129202771 40.6994595557025 3.38012176831219 0.000815108491157952 -155.652248524296 81.403371606173 -1.91211058526344 0.0567632081197298 CCSER2 other 0.0499605153700044 1 1 3.38012176831219 -1.91211058526344 2.22013327644914e-06 83.9022526116426 20.9309855785112 4.00851896328193 7.62268811216634e-05 -62.4616276815474 42.8430202062822 -1.45791840493048 0.145853009404545 BMPR1A ts 0.022347861560737 1 0.799924890490736 4.00851896328193 -1.45791840493048 1.17716503917252e-05 48.1179574661664 20.710285169597 2.32338459234758 0.0207887824536458 -123.541482672906 42.1714729691404 -2.92950361879247 0.00364050044821819 MINPP1 other 0.111618789014338 1 1 2.32338459234758 -2.92950361879247 0.884104174877818 82.6384153904964 352.54369028248 0.234406167712947 0.814820995553168 -213.232060803695 712.902852082627 -0.299103952496155 0.765056725479535 ACTA2 other 1 1 1 0.234406167712947 -0.299103952496155 0.0126241574866074 239.392296795519 112.35723270998 2.13063539410449 0.0338862045268701 -225.187257195595 225.728775411287 -0.997601022666669 0.319231355497896 LIPA other 1 1 1 2.13063539410449 -0.997601022666669 0.241085161115618 9.68406625894652 12.9824170581285 0.745937079018976 0.456253025470629 -24.0995216788894 23.7780652956313 -1.01351903021804 0.311578017469334 TLX1 other 1 1 1 0.745937079018976 -1.01351903021804 4.9816199578393e-07 96.2638629283495 26.5827572880115 3.62128961587305 0.000340712362420758 -100.309034267913 48.6878934563648 -2.06024592864779 0.0401832005809741 TWNK other 0.0052670667814235 1 1 3.62128961587305 -2.06024592864779 0.0267796642614874 143.201735017166 85.0637379653651 1.68346393472002 0.0932605476749164 -175.163447265538 155.799271166112 -1.12428925985655 0.261732986072896 LZTS2 other 1 1 1 1.68346393472002 -1.12428925985655 5.51744211849268e-07 87.8569705152988 64.0852676401829 1.37093865330463 0.17135480844827 -483.235828192706 117.375961010448 -4.11699145236127 4.88995925176901e-05 SFXN3 other 0.00581593573710313 0.705718919215304 1 1.37093865330463 -4.11699145236127 0.260799476598492 -14.4663242522924 20.911931282126 -0.691773708373703 0.489581051706054 -62.8864110914018 38.3014399597348 -1.64188111876505 0.101596989340535 KAZALD1 other 1 1 1 -0.691773708373703 -1.64188111876505 0.00621042612813465 51.5791043307964 56.3874834994039 0.914726125902421 0.361024163968678 -242.732333872858 103.432430549628 -2.3467720190177 0.0195462656608241 FBXW4 other 1 1 1 0.914726125902421 -2.3467720190177 0.000372790547542641 151.20403390952 61.6230053579251 2.45369457447396 0.0146724206982343 -198.400660842195 113.036029033115 -1.75519843132556 0.0801822577672827 NPM3 other 1 1 1 2.45369457447396 -1.75519843132556 5.29349451441396e-05 231.170981108589 75.6535160626252 3.05565416043886 0.00243526146484666 -231.366317772315 146.71046370584 -1.57702669549333 0.115780506683891 TNKS2 other 0.471012067568786 1 1 3.05565416043886 -1.57702669549333 1.47707713899876e-07 201.336689323395 100.682623480965 1.99971635980919 0.046378566300035 -732.0268509576 185.004883619018 -3.95679744576403 9.36629852950173e-05 GBF1 essential 0.00161459302063954 1 1 1.99971635980919 -3.95679744576403 5.01534950150748e-05 134.041922938037 82.8600285048715 1.61769100683035 0.106717539818959 -479.181236308196 166.458791580333 -2.87867785028912 0.00426313170073658 ARHGAP21 other 0.447569789514527 1 1 1.61769100683035 -2.87867785028912 0.0335858736715261 -4.384612806083 11.9592354918643 -0.36662985765819 0.71413819251677 -57.230987986258 23.1234884590625 -2.47501531127447 0.0138423414246976 CPEB3 other 1 1 1 -0.36662985765819 -2.47501531127447 0.0604269539688345 -8.72977164694847 27.1439683008426 -0.321610000063163 0.747958138820022 -112.636283044659 49.8692789567579 -2.25863067204816 0.0245792967233259 FBXL15 other 1 1 1 -0.321610000063163 -2.25863067204816 0.0160140111900739 -21.4587873140417 55.9861677251848 -0.383287304453038 0.701761253237233 -282.308847683656 102.85857193255 -2.74463121915382 0.00639993667147828 CUEDC2 other 1 1 1 -0.383287304453038 -2.74463121915382 6.70893619871911e-07 17.6743449081039 28.6518303172309 0.616866172681286 0.537761631448188 -241.784567496129 52.6395441843826 -4.59321164805723 6.2845717875843e-06 SUFU ts 0.00702693977453839 0.0929928087408849 1 0.616866172681286 -4.59321164805723 3.54481063857831e-07 25.0042256561649 9.40321579453357 2.65911430754368 0.00823379624585386 -55.7175428050899 18.4774914782999 -3.01542787182584 0.00277423865631711 ANKRD26 other 0.00379365634540651 1 1 2.65911430754368 -3.01542787182584 2.30390002435278e-08 73.3673621236002 31.7686603610015 2.30942574505484 0.0215624197036874 -240.665855165683 62.5959252271665 -3.84475274216786 0.000145842441892362 ACBD5 other 0.000262944109779383 1 1 2.30942574505484 -3.84475274216786 8.55309138542748e-06 84.3589376069501 28.1875734742634 2.99277047327163 0.00297969669222807 -126.444576293694 56.1028204449416 -2.2538007053992 0.024885091062414 LHPP other 0.0821182303914892 1 1 2.99277047327163 -2.2538007053992 7.37426426802516e-29 497.076623259487 60.922674103731 8.15913993553749 8.22044117511551e-15 -531.410472948814 120.72796202352 -4.40171824357712 1.47383573005887e-05 LARP4B other 1.11137536783407e-24 0.216079056383931 1.18193503215811e-10 8.15913993553749 -4.40171824357712 2.38371304516438e-27 662.216142706902 68.2482433960471 9.7030503607842 1.22051533122992e-19 -231.994571986418 135.244741930744 -1.71536851395832 0.0872641791170674 GTPBP4 essential 3.58057536514142e-23 1 1.808071411684e-15 9.7030503607842 -1.71536851395832 0.0704898218736351 -7.43050616321184 15.4242592832968 -0.481741523319598 0.63031886561921 -70.432317631672 31.2425979568715 -2.25436814598131 0.024848994557156 EDRF1 other 1 1 1 -0.481741523319598 -2.25436814598131 3.98918480445557e-06 120.811426269424 52.831615078553 2.28672597061049 0.0228645850765276 -337.629294071694 107.013042182122 -3.15502939816526 0.00175725078291433 BCCIP other 0.0394091566832165 1 1 2.28672597061049 -3.15502939816526 0.2316733948919 -6.91948925091306 30.6816802341602 -0.225525108080915 0.821715208588695 -91.9815003358367 56.4704511533008 -1.62884302245317 0.104333362256965 NEURL1 other 1 1 1 -0.225525108080915 -1.62884302245317 6.2131017503224e-05 528.564709007548 253.602145636082 2.08422806392985 0.0379322676492203 -1241.72587073458 466.694092084977 -2.66068478644568 0.00819131767862294 SH3PXD2A other 0.547933443360932 1 1 2.08422806392985 -2.66068478644568 1.78356942341256e-14 431.864622567628 76.5805239113982 5.63935319987214 3.77158933407319e-08 -404.917230811816 154.046804898962 -2.62853378281618 0.00899166239736177 PITRM1 other 2.43029169634195e-10 1 0.000477332346120303 5.63935319987214 -2.62853378281618 4.20930016299186e-07 61.9883301529875 26.0892175147526 2.37601339012698 0.0180891498084964 -167.437155998722 48.0109647760118 -3.48747742895556 0.000555798309994081 STN1 other 0.00447322328321145 1 1 2.37601339012698 -3.48747742895556 0.00082375127647246 55.0352282700835 21.3472718595155 2.57809188135447 0.0103887323091192 -58.0045442354285 46.6168534606482 -1.24428269883966 0.214320581970335 MAP3K8 other 1 1 1 2.57809188135447 -1.24428269883966 0.0270008662757215 180.934027837664 108.864973265449 1.66200406256002 0.0975004601233253 -284.51739017068 216.456567986807 -1.31443177177244 0.189651179273863 DKK1 other 1 1 1 1.66200406256002 -1.31443177177244 0.173765159052235 -10.6419512869644 16.6270783383813 -0.640037357759897 0.52260773131408 -62.7115585262175 33.5834263326169 -1.86733652204245 0.0627715697202283 EBF3 other 1 1 1 -0.640037357759897 -1.86733652204245 7.97825301462333e-07 246.817760701658 75.6008814663051 3.26474712879722 0.00121459910031946 -381.893385687063 152.698903663898 -2.50095695858852 0.0128869026623446 GLRX3 essential 0.00831605645479005 1 1 3.26474712879722 -2.50095695858852 6.6109825962311e-07 280.812582875083 77.6576401423198 3.61603291524762 0.000347581871203303 -292.735563756397 159.15238214371 -1.83934138976359 0.0667941644997971 FAM208B other 0.00692764866259057 1 1 3.61603291524762 -1.83934138976359 1.02236227167944e-06 47.2852591382718 59.838868069004 0.790209786116679 0.429990452178474 -504.46315968661 112.925207839549 -4.46723251024148 1.10048557201325e-05 XPNPEP1 other 0.0105794047873389 0.161804393653109 1 0.790209786116679 -4.46723251024148 0.00275335232564497 105.323003817706 86.9150943483798 1.21179185971475 0.226486085999338 -397.210057244471 164.022238561843 -2.42168416141149 0.0160042851887904 SMC3 essential 1 1 1 1.21179185971475 -2.42168416141149 1.34627501336326e-06 135.150111633051 37.6022265923752 3.59420502137116 0.00037663995700729 -142.483862798972 70.9612228673373 -2.00791160357181 0.045492877364125 SHOC2 other 0.0138100890870803 1 1 3.59420502137116 -2.00791160357181 6.31592052248924e-05 84.0638006284007 37.4830568903055 2.24271464503053 0.0256082099790071 -245.078463569456 85.7173454563313 -2.85914667871173 0.00453022070861101 TFAM essential 0.556179961210403 1 1 2.24271464503053 -2.85914667871173 1.07548799858767e-14 499.018845375715 75.1301355789673 6.64205969455772 1.35163410171441e-10 -450.984130132031 171.809780735065 -2.62490370572942 0.00908866571268895 CCDC6 other 1.47223552126666e-10 1 1.83200486146371e-06 6.64205969455772 -2.62490370572942 1.20432668567987e-17 130.384890387336 31.3080401138688 4.16458168295173 4.07827324288885e-05 -337.671860290962 63.0038369211552 -5.35954438320216 1.66262070405108e-07 CUL2 essential 1.7113482203511e-13 0.00250939342862429 0.438414373610552 4.16458168295173 -5.35954438320216 1.72309330363941e-20 449.025556921451 57.9460201481541 7.74903187092746 1.44297232678533e-13 -253.204022078264 116.50844198953 -2.17326759979348 0.0305423247392352 CCNY other 2.50916846875971e-16 1 2.04801062340642e-09 7.74903187092746 -2.17326759979348 0.294902425811533 30.4336608763136 70.8942283491621 0.429282631111018 0.668006433057467 -259.748373469019 192.632010416211 -1.34841749773463 0.178477729416747 UBE2S other 1 1 1 0.429282631111018 -1.34841749773463 0.0152981830650912 251.702881758071 144.254664434709 1.74485090478301 0.0819768534837694 -509.06933010601 339.449241918191 -1.49969205183465 0.134686304196657 ZMIZ1 other 1 1 1 1.74485090478301 -1.49969205183465 0.174578206001259 9.28293822496634 6.05650223220595 1.5327226621999 0.126335313410407 -5.37214465209937 12.7564903638641 -0.421130302995978 0.673943532628237 DNAJC12 other 1 1 1 1.5327226621999 -0.421130302995978 0.000746351541499499 846.591422420441 298.055281872316 2.84038389490146 0.00479548166423499 -919.91233737672 696.420087304203 -1.32091585832574 0.187476185784228 PPIF other 1 1 1 2.84038389490146 -1.32091585832574 0.0872701116398138 5.09971592879097 4.63007498639424 1.10143268603139 0.271536153666891 -12.9773901443686 9.69023919483409 -1.33922289052337 0.181448571718598 PBLD other 1 1 1 1.10143268603139 -1.33922289052337 1.47019036683234e-05 364.569506902298 168.487536040868 2.16377730643451 0.0312234278974918 -1229.91424395548 391.773913172225 -3.13934696161049 0.00185156791623442 TSPAN14 other 0.138300807807918 1 1 2.16377730643451 -3.13934696161049 4.09190771066794e-05 26.668914424799 9.62295569834604 2.77138493211423 0.00590945781115429 -33.9834726756017 17.7040565152789 -1.91953028653481 0.0558090373224795 TBC1D12 other 0.368762722885394 1 1 2.77138493211423 -1.91953028653481 0.479731555393209 -65.890522355887 60.4185066488391 -1.09056853620782 0.276288434873819 -4.56268989160716 111.330266141879 -0.0409833736119204 0.967334869606852 CYP2C18 other 1 1 1 -1.09056853620782 -0.0409833736119204 2.65852552671845e-05 620.207537442861 134.301347643903 4.61802914358929 5.62591466963115e-06 -123.680037342819 391.663388984734 -0.31578146138045 0.752374889973888 KRT23 other 0.244052643352753 1 0.0642085641245003 4.61802914358929 -0.31578146138045 1.20208506804334e-14 461.889727453762 60.709723993263 7.6081671447727 3.21938980867717e-13 -497.53395782884 191.831608815705 -2.59359737897432 0.00993984478234655 NUFIP2 other 1.64313007950844e-10 1 4.54610034883304e-09 7.6081671447727 -2.59359737897432 3.37705628960423e-11 546.607815672555 84.115805345116 6.49827714815183 3.16068439962483e-10 -430.954247099142 203.066137247576 -2.12223590274792 0.0345955155939707 GIT1 other 4.28683525402361e-07 1 4.25206872281529e-06 6.49827714815183 -2.12223590274792 0.0839649269632182 1211.45003039419 603.546354616707 2.00721953024395 0.0455775504307819 -1216.52687381083 1478.41848832426 -0.822856913261221 0.411209878102135 RPL19 essential 1 1 1 2.00721953024395 -0.822856913261221 2.92214082529956e-05 70.8964821074186 15.308227900035 4.63126643857035 5.32352803403738e-06 -0.307021741299322 37.4848074312989 -0.00819056472044101 0.99347013264781 FBXL20 other 0.267375885514909 1 0.0608798665972515 4.63126643857035 -0.00819056472044101 0.970850625035426 -2.93574766980042 13.730224957736 -0.213816428997861 0.830826382927506 3.28015323418203 33.1012116898875 0.0990946574679054 0.921125160876384 RUNDC3A other 1 1 1 -0.213816428997861 0.0990946574679054 0.002679454364074 233.719160382089 67.5298859687547 3.46097371599632 0.000611286725876172 -4.51308028352882 162.802944432914 -0.0277211219935184 0.977901857001553 UBTF essential 1 1 1 3.46097371599632 -0.0277211219935184 0.403000348286209 -76.3032860556372 73.5014722167923 -1.03811915264202 0.300008276732298 -199.845928053139 212.555427743688 -0.940206186097135 0.347829949937994 CSF3 other 1 1 1 -1.03811915264202 -0.940206186097135 1.30191770813705e-18 916.559966679091 99.8468671430676 9.17965673740949 5.81525633411396e-18 -699.655729223755 288.742428068173 -2.42311368614856 0.0159496651004043 PSMD3 essential 1.86708018523934e-14 1 8.53912240101294e-14 9.17965673740949 -2.42311368614856 7.36082769909746e-08 1015.16320889142 178.300003597638 5.69356807856436 2.84388239082108e-08 -537.783129096609 515.61733919581 -1.04298883729428 0.297750714517791 RAPGEFL1 other 0.000817493524261764 1 0.000361741840112441 5.69356807856436 -1.04298883729428 0.353566299061064 15.6239006481235 10.8190373060132 1.44411191182785 0.149691993937415 3.63827277796701 25.0323256090457 0.145342979105876 0.884532162416235 RGS9 other 1 1 1 1.44411191182785 0.145342979105876 0.0173360071949818 -74.6258487370203 41.1175877922276 -1.81493742079701 0.0704784899330499 -237.789245894396 96.2937675765771 -2.46941470750218 0.0140600039450247 RNF43 other 1 1 1 -1.81493742079701 -2.46941470750218 0.392982985201868 7.96373812504602 15.6906736394736 0.5075459669884 0.612124721565763 -43.3142526450157 36.7461750965118 -1.1787418018679 0.239385009054965 RAD51C essential 1 1 1 0.5075459669884 -1.1787418018679 0.862581132243604 -0.386538036674285 7.47312841633332 -0.0517237246759289 0.95878141047953 9.2258408817537 17.5014082642353 0.527148486708181 0.598459188729677 SEPT4 other 1 1 1 -0.0517237246759289 0.527148486708181 0.000194129599831338 150.270005155019 39.5390550244559 3.80054619570632 0.000173107599379853 -107.866241745833 92.5969829252033 -1.16490017642328 0.244935258009087 MTMR4 other 1 1 1 3.80054619570632 -1.16490017642328 3.09514915987341e-06 97.8670340390758 23.5561524954087 4.15462729145394 4.19188060039774e-05 -130.231900170796 55.1824653729505 -2.36002323003555 0.0188774415241009 TRIM37 other 0.0308524468256181 1 0.450207976482717 4.15462729145394 -2.36002323003555 0.0388454166266448 -3.73507617419519 2.48205114191048 -1.50483449399042 0.13335299432925 -10.0612759345837 4.70395958984925 -2.13889506115127 0.0332008031082264 P2RX1 other 1 1 1 -1.50483449399042 -2.13889506115127 0.116716874888026 79.2148422372377 41.6282022523681 1.90291287999907 0.0579605895675221 -54.3683229320372 97.4941987034169 -0.557657005802252 0.577473445019699 DHX40 other 1 1 1 1.90291287999907 -0.557657005802252 0.578001275381955 -0.777274216121251 4.05630188469214 -0.191621392642043 0.848160695885692 -12.3283957444455 11.8326791613874 -1.04189385821225 0.29824986077045 KRT37 other 1 1 1 -0.191621392642043 -1.04189385821225 0.0172728520218275 31.9256140870729 11.1336225571426 2.86749563524511 0.00441809413576274 8.38054464543757 25.657705837275 0.326628760131099 0.744166990735018 TUBD1 other 1 1 1 2.86749563524511 0.326628760131099 1.14879899871873e-07 850.376655998547 175.311782340949 4.85065318852742 1.92727377757006e-06 -1150.7883280839 416.910340616214 -2.76027772873894 0.0061092321413808 KPNB1 essential 0.00126356401869073 1 0.0226030668633417 4.85065318852742 -2.76027772873894 6.33377227164215e-08 76.9549910513449 13.7994334315151 5.57667758124007 5.23130914968242e-08 -49.7101498970877 33.1789087759653 -1.49824547373594 0.135058357402353 GOSR2 essential 0.000705962257397235 1 0.000658621821945017 5.57667758124007 -1.49824547373594 0.000173537114325787 69.2355967130378 19.8962627878398 3.47982922478051 0.000571533766066596 -99.0288598385375 47.3304221867509 -2.09228769284586 0.0372028711839728 PNPO other 1 1 1 3.47982922478051 -2.09228769284586 0.00052044720068917 104.758845790561 33.7084536843086 3.10779149858561 0.00205842099300863 -159.131544490042 77.8036210541052 -2.04529740819365 0.0416640664283608 RPS6KB1 other 1 1 1 3.10779149858561 -2.04529740819365 0.00336738424816926 318.197463030365 101.629857763418 3.13094468528225 0.00190320328530287 -222.305728973505 189.252062919999 -1.17465419157665 0.241006457551978 TRIM16L other 1 1 1 3.13094468528225 -1.17465419157665 0.774660107171396 28.2283479346014 75.7434066680474 0.372683896544485 0.70963121544746 -104.062324670647 180.182954642744 -0.577537008852895 0.563984145856148 CDK5RAP3 other 1 1 1 0.372683896544485 -0.577537008852895 3.04517450976775e-07 394.413193604092 74.5667033315374 5.28940097901952 2.28398937441961e-07 -251.826534451935 177.327668850687 -1.42011980467627 0.156549375726007 CBX1 other 0.00326929935368666 1 0.00280336855816263 5.28940097901952 -1.42011980467627 3.11230212942116e-06 108.897227804825 22.7644185275645 4.78365953749117 2.63844405932015e-06 -62.3251274690703 56.1014841357253 -1.11093544902107 0.267435401112202 RECQL5 other 0.0310140907196818 1 0.030748427067317 4.78365953749117 -1.11093544902107 1.33588725001253e-19 64.1487960932197 6.6349145309784 9.66836811442093 1.44251145646161e-19 -24.3707562154515 14.1080680625142 -1.72743398369375 0.085054624976855 PIGL other 1.93396397184313e-15 1 2.13592671358271e-15 9.66836811442093 -1.72743398369375 0.00903247760844588 76.616283967951 24.8465883693084 3.08357360089689 0.00222513492924563 42.5409495963016 61.216479385992 0.694926431950873 0.487610449584791 GALK1 other 1 1 1 3.08357360089689 0.694926431950873 4.16812780573224e-07 79.7162446606213 15.6170017385212 5.1044525700469 5.76902399782598e-07 -57.2231746237278 35.8513911631661 -1.59612145490519 0.111470796902215 INTS2 essential 0.00443071985749337 1 0.00695340462457965 5.1044525700469 -1.59612145490519 1.21083736833723e-24 221.075222728772 19.9771984733167 11.0663776517043 2.5580995136447e-24 -125.047405860028 44.5928392949233 -2.80420372053465 0.005352281937062 CAMTA2 other 1.80233142276997e-20 1 3.84917233818119e-20 11.0663776517043 -2.80420372053465 5.91454102490695e-05 285.969895468525 74.0633814119264 3.86115094959026 0.000136965769671385 -310.453841943422 170.548669259963 -1.82032403589268 0.0696584996077857 MED13 other 0.523022862832522 1 1 3.86115094959026 -1.82032403589268 0.590518207051993 -3.32752209481314 3.59857803174028 -0.924676932239245 0.355832923656784 3.33548458695817 8.58337808920489 0.388598119795413 0.697832687397387 HOXB6 other 1 1 1 -0.924676932239245 0.388598119795413 0.0750614062654849 1059.02777012544 464.260031468307 2.28110907324086 0.0231987960512343 190.231702568306 1039.97860731781 0.182918861243626 0.854977519022212 ENO3 other 1 1 1 2.28110907324086 0.182918861243626 1.71397026637851e-15 3575.50293289612 425.89726106514 8.39522405932838 1.52439395056613e-15 -2015.87178997889 954.04301555352 -2.11297788162027 0.0353766645566272 PFN1 essential 2.37436301001415e-11 1 2.2061029252593e-11 8.39522405932838 -2.11297788162027 2.17224462845944e-29 661.807275463784 52.5750668270831 12.5878541940886 8.62714497101651e-30 -228.745232964832 117.77224200314 -1.94226779650449 0.0529818355397963 RNF167 other 3.27856881773384e-25 1 1.30994569239915e-25 12.5878541940886 -1.94226779650449 1.18242342853563e-32 650.898245637608 48.0861705181113 13.5360798879264 2.55899443719759e-33 -166.642534721056 107.716764866687 -1.54704362804896 0.122841094898169 SLC25A11 other 1.79338161405999e-28 1 3.89709262840821e-29 13.5360798879264 -1.54704362804896 0.389172028173989 56.8320469341978 43.7457425084052 1.29914464072197 0.194832474892411 42.7063738984009 81.8981266770184 0.521457274191655 0.602410092712321 RASD1 other 1 1 1 1.29914464072197 0.521457274191655 1.54206974937386e-28 184.033320119062 14.7094146183895 12.511260637727 1.64957842831397e-29 -23.3285196175063 32.9502336888918 -0.707992539226539 0.479465246325234 CHRNE other 2.32251124953197e-24 1 2.50389509633778e-25 12.511260637727 -0.707992539226539 1.95068515601309e-06 311.946811066663 73.1118127843607 4.26670874632438 2.62034626511126e-05 -383.528253590692 137.122960511147 -2.79696596515296 0.00547267092982179 RAI1 other 0.0197253282976044 1 0.285722556747732 4.26670874632438 -2.79696596515296 9.49696207935697e-12 246.839148173201 35.096086598025 7.03323852030532 1.22836333590184e-11 -135.943011836162 65.7445397293297 -2.06774604242176 0.0394673224297451 NUP88 essential 1.22159423226769e-07 1 1.6968611122148e-07 7.03323852030532 -2.06774604242176 5.97837461576943e-11 692.064132550881 97.1787558214147 7.12155786211841 7.08132481789419e-12 63.4449185320835 182.042307056176 0.348517438380437 0.727680799966903 C1QBP essential 7.53693687810052e-07 1 9.82038125745566e-08 7.12155786211841 0.348517438380437 0.81342116408039 -0.663884074270481 9.4214090880856 -0.0704654758182653 0.943867751250006 14.2200691881427 22.8312235837611 0.622834301279275 0.533842629554648 SLC6A4 other 1 1 1 -0.0704654758182653 0.622834301279275 0.001630841217558 150.650766090822 60.2561585809883 2.50017209258929 0.0129197251495325 -328.160488571856 146.587309562441 -2.23866915595495 0.0258733558073101 BLMH other 1 1 1 2.50017209258929 -2.23866915595495 0.0544226908443813 196.049077309031 124.776202161443 1.57120567794947 0.11713876831799 -491.245310362909 303.441716556844 -1.61891158518701 0.106467041853746 CPD other 1 1 1 1.57120567794947 -1.61891158518701 9.56302985577131e-06 88.7911605567327 26.5060847657674 3.34984066267707 0.000906830162919569 -199.299110970951 64.4598226360428 -3.09183461605605 0.00216706374318291 GOSR1 other 0.0914225654211737 1 1 3.34984066267707 -3.09183461605605 2.2357874334521e-08 481.797863490263 85.1881869846639 5.65568866463844 3.4515380402675e-08 -316.058895821516 196.443624233582 -1.60890381174043 0.108626538117575 CCDC47 other 0.000255304567025896 1 0.000437447931223503 5.65568866463844 -1.60890381174043 0.00074213223534082 40.0336727580807 10.7221956005097 3.73371968295168 0.000223274909231261 -14.8783350702136 20.4665049858536 -0.726960225035852 0.467781789493904 MED31 other 1 1 1 3.73371968295168 -0.726960225035852 4.84185077443481e-20 223.338489366002 22.4735215315979 9.93785015187705 1.88472071466548e-20 -61.3668194032615 41.9002850684171 -1.46459193065294 0.144017085610528 DRG2 other 7.03085150955679e-16 1 2.80408747927931e-16 9.93785015187705 -1.46459193065294 3.10021962067992e-12 408.524324068823 56.9317089413908 7.1756905187825 5.06849746737443e-12 -212.185668368311 131.284296967978 -1.61623037384331 0.107032994867049 FTSJ3 essential 4.03648594612526e-08 1 7.04115668167656e-08 7.1756905187825 -1.61623037384331 2.97935636998669e-12 95.4360191482729 15.7614218677344 6.0550386855416 3.93170436160131e-09 -121.171219695235 28.8347788028487 -4.20225938002561 3.43192091249966e-05 AKAP10 other 3.88061167190766e-08 0.49790308598545 5.1477805206446e-05 6.0550386855416 -4.20225938002561 0.156286209876523 2067.88216146658 1091.79816271837 1.89401505889875 0.0591246500852857 -526.059391758051 1997.39330521873 -0.263372962342257 0.792432634250148 ALDH3A1 other 1 1 1 1.89401505889875 -0.263372962342257 3.10909878828113e-05 408.006929476272 90.9709508409106 4.48502434793489 1.01856096327816e-05 -129.038183021365 209.778654948728 -0.615115885135707 0.538916736487426 SMARCD2 other 0.283611991467004 1 0.114221426422013 4.48502434793489 -0.615115885135707 0.664187934282979 -15.5654359787552 17.846774945482 -0.872170799839422 0.383773238581606 5.70646994765189 41.0261171815322 0.139093590612095 0.889464238464347 ICAM2 other 1 1 1 -0.872170799839422 0.139093590612095 0.107997868612851 324.566082935643 242.574687688197 1.3380047441423 0.181844913427002 -767.687611838977 571.774072228889 -1.34264152420619 0.180339710034991 SYNGR2 other 1 1 1 1.3380047441423 -1.34264152420619 3.06502332251417e-07 55.4305067241366 9.98089112751093 5.55366309640931 5.88701981911116e-08 -10.1425703182866 18.5638790304772 -0.546360504808024 0.585198880588422 B9D1 other 0.00328999603438671 1 0.000739762910469508 5.55366309640931 -0.546360504808024 8.17966348647961e-10 170.690696316061 28.2994948698921 6.03158102647476 4.53383463462762e-09 -138.83681946427 69.632213323398 -1.99385906088407 0.0470266382028506 UTP6 other 9.92683960719165e-06 1 5.92300156667753e-05 6.03158102647476 -1.99385906088407 0.0849194180401425 29.700310871389 15.8408697680593 1.87491667479491 0.0617263602020233 -37.1323803486771 39.2808736831422 -0.945304339414755 0.345225760468628 C17orf75 other 1 1 1 1.87491667479491 -0.945304339414755 0.000835423902112058 205.969050170906 70.8123333079992 2.90866068873964 0.00388453994160471 -300.350920427553 166.276820189798 -1.80633067245763 0.0718090365605201 CYTH1 other 1 1 1 2.90866068873964 -1.80633067245763 5.16978882338709e-08 573.22501867944 114.509529711065 5.00591540394781 9.25456033821795e-07 -715.239850692974 283.951224772137 -2.51888278089638 0.0122660706212914 PSMD11 essential 0.000578912952442886 1 0.0110527214119337 5.00591540394781 -2.51888278089638 0.000171231603140953 1879.60455224284 739.173831312766 2.54284509626738 0.0114675082430172 -4872.93807119931 1737.80690902004 -2.80407336736115 0.00535537358587183 LGALS3BP other 1 1 1 2.54284509626738 -2.80407336736115 0.711541551689711 -48.5151417414577 82.4969102372284 -0.588084348879824 0.556897055836746 -132.211593414637 203.014412285875 -0.65124240159099 0.515364825904622 CCL2 other 1 1 1 -0.588084348879824 -0.65124240159099 0.0532528999703652 -15.0772501035379 6.25646858221014 -2.40986587008669 0.0165295458313828 -9.95036484725085 15.4003624924753 -0.646112378985405 0.51867551675183 CCL8 other 1 1 1 -2.40986587008669 -0.646112378985405 0.00422902588462214 18.446019384352 5.69733910845139 3.23765516379204 0.00133233076352643 -5.54603609500002 13.8655909266709 -0.399985555922615 0.689435698953755 PEX12 other 1 1 1 3.23765516379204 -0.399985555922615 0.796521308675892 0.88185689187982 4.50412812051842 0.195788589552448 0.844900297666752 -8.26430804701357 13.1390375930864 -0.628988842482814 0.529806505915419 KRT32 other 1 1 1 0.195788589552448 -0.628988842482814 0.179971005776977 -6.59685453200864 24.6380430901304 -0.267750750653214 0.78906367976394 -117.839291040656 63.5682989282931 -1.85374302958117 0.064696056415227 DHX58 other 1 1 1 -0.267750750653214 -1.85374302958117 5.98974147811125e-08 344.102981533866 58.644450128299 5.867613743177 1.10388325745049e-08 -42.984228325162 151.307793504689 -0.284084694710916 0.776529205376833 KAT2A other 0.000668335354127653 1 0.000142445095541411 5.867613743177 -0.284084694710916 5.21008079911355e-12 503.86628048974 70.0269713210047 7.19531733251763 4.45409944268708e-12 -276.741970467723 180.675690422825 -1.53170562027509 0.126583071955009 RAB5C other 6.75174370757124e-08 1 6.19476150488919e-08 7.19531733251763 -1.53170562027509 3.11530461496715e-05 124.697776402122 26.9988655551773 4.61863022160241 5.60439550686455e-06 50.9080797889895 69.6425590687843 0.730990941023703 0.465319579913146 NAGLU other 0.284084627838854 1 0.063968570315352 4.61863022160241 0.730990941023703 0.00788683100287941 67.5592695591627 23.8039957051658 2.83814828384049 0.00482743037984862 -66.4054913802407 61.4015123554774 -1.08149602237471 0.28029086452832 HSD17B1 other 1 1 1 2.83814828384049 -1.08149602237471 4.33496547929717e-06 138.472719124768 31.4710088955021 4.40000889658669 1.47636669502882e-05 -172.161835994201 81.178284749781 -2.12078681540096 0.0347085534548016 MLX other 0.0426994099710771 1 0.163714302811746 4.40000889658669 -2.12078681540096 0.0755768842488422 29.9241791900267 15.2388004163115 1.96368338534024 0.0504323433909597 -38.6257184490879 38.5925109739879 -1.0008604642264 0.317650489692019 CNTNAP1 other 1 1 1 1.96368338534024 -1.0008604642264 0.0100225267824354 -51.0513524530365 17.0184189907908 -2.99977057097149 0.00291527957529527 -31.2458108580706 40.5907424094759 -0.769776776755291 0.442003745792828 ABI3 other 1 1 1 -2.99977057097149 -0.769776776755291 0.121166717985797 2.04863959590898 20.3096736472863 0.10087013860918 0.919716717735783 -105.13838949397 51.4345802621074 -2.0441187418696 0.0417600686383544 EZH1 other 1 1 1 0.10087013860918 -2.0441187418696 0.0560803127998648 27.2130268596829 12.2405388249749 2.22318863971568 0.0269034396140843 31.2761649861351 29.1963024904983 1.07123718821291 0.284872591338765 DLX4 other 1 1 1 2.22318863971568 1.07123718821291 0.0003273769821958 285.747401373252 75.270862861914 3.79625515782198 0.000175802843581402 -213.674676432777 179.537103085147 -1.19014216427142 0.234875476575228 PPP1R9B other 1 1 1 3.79625515782198 -1.19014216427142 0.0191013270929182 36304.1064701916 13080.7843738066 2.77537687593782 0.00583911632258867 22832.1697711826 31200.4677940658 0.731789341168954 0.464834406020107 COL1A1 other 1 1 1 2.77537687593782 0.731789341168954 0.00854733396398645 58.782372576489 26.2396341035252 2.24021311976266 0.0257653242138811 143.478844901042 62.5871381546873 2.29246533922716 0.0225294776222275 SGCA other 1 1 1 2.24021311976266 2.29246533922716 0.00697180561773483 82.6596098303961 26.2724068337639 3.14625189665403 0.00180920092487369 -11.3363769578988 64.340072166689 -0.176194657173045 0.860252469329077 PTGES3L-AARSD1 other 1 1 1 3.14625189665403 -0.176194657173045 0.848442005479179 -6.06899116207477 57.6607096960307 -0.10525349400083 0.916240814801768 -78.2875271681171 137.533122207598 -0.569226713619914 0.569602868694757 MRPL27 essential 1 1 1 -0.10525349400083 -0.569226713619914 4.98474617669629e-09 701.110800312287 116.042128350188 6.04186436667636 4.23097201655488e-09 -433.98154356507 284.182525022115 -1.5271225545318 0.1277183246508 VAT1 other 5.87053557229523e-05 1 5.53368830045213e-05 6.04186436667636 -1.5271225545318 4.30989045498859e-09 894.448987357101 159.276474371962 5.61570056647709 4.26243214587267e-08 -1029.40535089389 379.908449446337 -2.70961425678765 0.00710019208967335 LRRC59 other 5.08868766020503e-05 1 0.000538345180023718 5.61570056647709 -2.70961425678765 0.0141353491822357 21.6038959483861 8.98910392983143 2.40334254860387 0.0168146191490486 41.397591960278 22.0139555244685 1.88051583525117 0.060945852656163 RND2 other 1 1 1 2.40334254860387 1.88051583525117 0.0110585061928646 194.706904351915 65.327076641456 2.98049314866105 0.00309835903984487 79.3793034124171 124.696189997695 0.636581626221975 0.524852485725312 ALOX12 other 1 1 1 2.98049314866105 0.636581626221975 1.39227783596758e-06 280.65091838265 53.6987233356661 5.22639833778404 3.13006707966942e-07 -64.3389648351835 129.416522736107 -0.497146449888604 0.619428244515616 HDAC5 other 0.0142680632629957 1 0.00381805582378076 5.22639833778404 -0.497146449888604 0.0420564551099721 189.009515829455 74.7351208239824 2.52905881124637 0.0119184660402957 17.3145992085553 180.274213511275 0.0960459006937917 0.923544426412734 ABCC3 other 1 1 1 2.52905881124637 0.0960459006937917 0.800250907107071 -6.77077980703563 73.733035234796 -0.0918283071553301 0.92689191129514 -118.468164953825 177.861815509046 -0.666068569101045 0.505847144663818 LUC7L3 essential 1 1 1 -0.0918283071553301 -0.666068569101045 0.583834351253526 8.89489104242159 11.3945336052275 0.780627917788652 0.435602062221894 -17.100152557946 27.6756928935825 -0.617876221697459 0.537099168369951 MPP2 other 1 1 1 0.780627917788652 -0.617876221697459 2.18035765928525e-07 125.408566441929 22.8928469530289 5.47806774313564 8.7534407700473e-08 -43.1281824516517 53.137029700454 -0.81164082175416 0.417604861893428 SMURF2 other 0.00236176341653778 1 0.0010925169425096 5.47806774313564 -0.81164082175416 2.04387354774419e-06 265.037680079052 50.7239350736152 5.22510092512352 3.1559216698619e-07 64.9840230223812 123.201185593709 0.527462643392771 0.598240156803643 DUSP3 other 0.0206226840967389 1 0.00384738410772864 5.22510092512352 0.527462643392771 0.177513960622759 16.3837238245373 11.9710832435446 1.36860829477334 0.172087809137002 40.0645748786676 28.1808083901397 1.4216971466541 0.156094175948999 CACNG1 other 1 1 1 1.36860829477334 1.4216971466541 3.31014930332093e-13 568.215397048223 79.1321842777188 7.18058527304187 4.91470705251806e-12 -530.098317168725 192.169092213258 -2.75849935628801 0.00614177957562979 EFTUD2 essential 4.40183654355617e-09 1 6.8304598615896e-08 7.18058527304187 -2.75849935628801 0.194926417064081 -73.9644969678508 44.0902867831848 -1.67756896959127 0.0944200334856155 -88.0028036889333 105.496634644048 -0.83417640748314 0.404811723479556 HLF other 1 1 1 -1.67756896959127 -0.83417640748314 0.499575213636002 5.04092727917122 11.0562484975074 0.455934694332141 0.648748136300975 -26.4426152335243 25.8698187879496 -1.02214149431311 0.30749088619455 SLC16A6 other 1 1 1 0.455934694332141 -1.02214149431311 0.00257298171255025 384.824260319607 145.332473367602 2.64788901889971 0.00850468195929215 -650.875902577418 339.925590297794 -1.91475993910083 0.0564229775153545 PRKAR1A other 1 1 1 2.64788901889971 -1.91475993910083 2.37899280387772e-15 109.584253039379 13.5015322052579 8.11643088898481 1.06233517978944e-14 85.1539287159727 25.7450494303702 3.30758458810807 0.0010488476169458 EFNB3 other 3.28919545064133e-11 1 1.52615071928551e-10 8.11643088898481 3.30758458810807 0.646394245354259 4.47085222536741 37.4497741991581 0.119382621683949 0.905047849190584 -79.2420136467073 87.5932013416469 -0.904659407727698 0.366332863037285 FAM20A other 1 1 1 0.119382621683949 -0.904659407727698 3.30096058249783e-22 2833.98106356832 266.806013138969 10.6218785334955 9.52887740984172e-23 -700.186375242062 509.611689549175 -1.37396058528696 0.170424637540086 YWHAE other 4.8590139774368e-18 1 1.42847401250937e-18 10.6218785334955 -1.37396058528696 0.14569990833302 33.6100072084362 17.2548717064686 1.94785610581134 0.0523174163885208 -4.61516444757391 41.2864381036748 -0.111784030290642 0.911065620747956 MMD other 1 1 1 1.94785610581134 -0.111784030290642 6.42767722046191e-11 170.801982194037 24.3662656275711 7.00977264241796 1.42805358021087e-11 -43.3944650589564 46.2110498182946 -0.939049539657437 0.348415779401758 RANGRF other 8.09565945917178e-07 1 1.97014271925892e-07 7.00977264241796 -0.939049539657437 1.37112690293044e-16 290.565863484032 33.3134419963186 8.72218077964272 1.53424169358048e-16 -125.598229448229 63.3761510951785 -1.98179010996747 0.048360782271355 DPH1 essential 1.92410238288229e-12 1 2.23523672337741e-12 8.72218077964272 -1.98179010996747 0.31611739770739 4.15315778271716 6.95234008618397 0.597375521224936 0.550680480786819 23.8907290667849 16.2846522580677 1.4670702627346 0.143342106756028 MAP2K6 other 1 1 1 0.597375521224936 1.4670702627346 5.44300257679075e-06 50.469837573917 16.7932676767413 3.00536134750105 0.00286234328214161 -117.143991303301 30.9159870492731 -3.789107270507 0.000180614582021924 DHRS7B other 0.0531726921726689 1 1 3.00536134750105 -3.789107270507 0.0096993481744557 162.862915238732 73.8761480946713 2.20453988789488 0.0282279335037694 -321.316863004172 179.444540229298 -1.79061933338058 0.0743395717739895 WSB1 other 1 1 1 2.20453988789488 -1.79061933338058 0.0654597773811618 529.349677299416 247.202457981794 2.14136089754578 0.0330294059481137 481.013649773899 468.601596165067 1.02648743348382 0.305467361258641 MYH1 other 1 1 1 2.14136089754578 1.02648743348382 0.0194131591506171 124.320442455459 82.0143132444291 1.51583836451748 0.130582514760931 379.912294367796 155.800191627092 2.43845845374257 0.0153130757672537 MYH3 other 1 1 1 1.51583836451748 2.43845845374257 4.41068628231328e-06 105.806683498449 21.5837438641756 4.90214691965767 1.50975021515192e-06 -26.8284680872436 51.2301213166235 -0.523685429543149 0.600859833909746 NAT9 other 0.0434143850768096 1 0.0178331695413745 4.90214691965767 -0.523685429543149 6.63792530199664e-08 128.845783112359 24.248941515115 5.31346009606426 2.01968231629406e-07 -100.573569424724 57.5561044199084 -1.74740056573281 0.0815271187892574 TMEM104 other 0.000738734706859206 1 0.00248441121727332 5.31346009606426 -1.74740056573281 2.21083482542484e-11 431.173348882035 75.6564134887153 5.69909845047502 2.80334847481323e-08 -915.635794874132 242.296417035135 -3.77899023880885 0.000188821281857228 TNFAIP1 other 2.81991981982939e-07 1 0.000356726093419983 5.69909845047502 -3.77899023880885 4.01326267190066e-14 130.250083661895 15.7881861368946 8.24984469606169 4.58435984660768e-15 76.0006997992296 50.5630753039059 1.5030869729033 0.13383462585776 IFT20 other 5.42874041628002e-10 1 6.60835471888497e-11 8.24984469606169 1.5030869729033 7.3826134516737e-13 294.131877344216 38.2941996178265 7.68084671515874 2.08830063411995e-13 -60.4625809277436 122.640592287811 -0.49300626978261 0.622357190234112 TMEM97 other 9.75243236966095e-09 1 2.95682486785044e-09 7.68084671515874 -0.49300626978261 8.76543542836151e-09 260.067109521376 41.5876220696571 6.25347390831284 1.28376254788562e-09 54.510565391205 98.5995709409434 0.552847896507119 0.580753551829722 CDR2L other 0.000102047199256985 1 1.70355290104422e-05 6.25347390831284 0.552847896507119 4.65782316131245e-16 471.000134538824 57.7228744977518 8.15967913304748 7.83640407377708e-15 498.447715814341 120.282864782341 4.14396278901664 4.37791891102096e-05 PMP22 other 6.49859487466314e-12 0.63287195777719 1.12718836197209e-10 8.15967913304748 4.14396278901664 0.000194837078464148 166.275527479812 51.0804588752365 3.25516902434136 0.00125816137326715 -360.373276796888 163.600706643954 -2.20276112609448 0.0283448399423742 FOXN1 other 1 1 1 3.25516902434136 -2.20276112609448 6.5064349808674e-12 153.469354165833 20.8095042894431 7.37496444082477 1.50240933794977e-12 -21.8875276455426 66.6487670946459 -0.328401088267106 0.742829421534498 UNC119 other 8.41021785626921e-08 1 2.10427451873244e-08 7.37496444082477 -0.328401088267106 0.00431590243194619 189.729216825442 60.4897790480218 3.13655000582527 0.001872445464006 -137.351937161887 193.749817551464 -0.708913891624198 0.478907277869903 ALDOC other 1 1 1 3.13655000582527 -0.708913891624198 2.3774069687116e-25 673.156319763361 61.6217050450235 10.9240132072218 9.47868601224357e-24 -531.765539696159 195.812092339372 -2.71569305727314 0.0069810755266034 SUPT6H essential 3.54946860428641e-21 1 1.42388821275923e-19 10.9240132072218 -2.71569305727314 1.43559025541852e-11 512.646058995191 69.791742392769 7.34536839774193 1.79200864458482e-12 116.522920716412 221.773595780148 0.525413858699057 0.599667520920483 RAB34 other 1.83841688108895e-07 1 2.507736897232e-08 7.34536839774193 0.525413858699057 5.94952414658271e-14 211.406561057114 26.8747941562999 7.86635089473072 5.88942121437139e-14 -108.493436433519 85.0127057925808 -1.27620260315237 0.202824057119542 PHF12 essential 8.03007274064268e-10 1 8.40420407290797e-10 7.86635089473072 -1.27620260315237 2.06209122082018e-22 460.657374524159 69.3717169855337 6.6404205422827 1.35332936323849e-10 -493.728870266737 133.152710341118 -3.70798963837743 0.000246423229472634 TMEM33 other 3.03828520475645e-18 1 1.83416728599713e-06 6.6404205422827 -3.70798963837743 1.97923216392279e-19 354.436300791678 59.29836943462 5.97716773953565 6.47639923687968e-09 -561.268457256277 130.327942964 -4.30658571363559 2.25311299180307e-05 SLAIN2 other 2.85801124470452e-15 0.328503874204887 8.4238524874094e-05 5.97716773953565 -4.30658571363559 1.20614385027533e-17 290.219236760648 57.0555039240577 5.08661245279575 6.49467272629801e-07 -573.149599536566 122.799152296238 -4.6673742352383 4.63572829373235e-06 OCIAD1 other 1.71368918247118e-13 0.0687849364224005 0.0078065966170102 5.08661245279575 -4.6673742352383 0.000122146036886859 150.62057921031 50.0097983549283 3.01182136631164 0.00282171761215182 -142.553572316612 107.634854170512 -1.32441831612262 0.18638929739271 CWH43 other 1 1 1 3.01182136631164 -1.32441831612262 8.06925219067533e-06 80.3430887929912 22.3243581062075 3.59889804718063 0.00037352752104264 -82.946750359618 47.4540094618683 -1.7479397694787 0.0814940798459881 DCUN1D4 other 0.0776584830830594 1 1 3.59889804718063 -1.7479397694787 1.04045605433426e-05 115.387302210018 28.7273103980031 4.0166413288046 7.46207567207127e-05 -62.8059500457692 61.0645131633957 -1.02851798519565 0.304532011365627 USP46 other 0.0991762710991421 1 0.784114911621249 4.0166413288046 -1.02851798519565 0.194528996157046 -51.8404099017322 52.359356671598 -0.990088748165478 0.322883489675844 -200.153512121681 113.048354112462 -1.77051239439156 0.0775998266724329 SULT1E1 other 1 1 1 -0.990088748165478 -1.77051239439156 0.494389031363738 270.512138893423 374.974102719736 0.721415524249177 0.471182303828724 -509.216726511071 806.217735493987 -0.631611913373579 0.528092844082198 ODAM other 1 1 1 0.721415524249177 -0.631611913373579 0.195243999751543 216.74509957005 124.823199148571 1.73641679630457 0.0834586264705593 32.3226825496885 267.029718089885 0.121045263354577 0.903731631238382 SMR3A other 1 1 1 1.73641679630457 0.121045263354577 7.05949755291828e-11 42.5511488365288 13.0517438678506 3.26018877380379 0.00123807254969119 -127.22257087248 27.7732756316058 -4.58075498763643 6.7363266446563e-06 CHIC2 other 8.87731817279473e-07 0.0996195512897526 1 3.26018877380379 -4.58075498763643 0.20758495494468 -64.1528380961119 73.7657518376749 -0.869683240500054 0.385135737290065 -277.268678570865 157.218105329471 -1.76359254546296 0.0787700093497518 NMU other 1 1 1 -0.869683240500054 -1.76359254546296 0.861641211007263 -3.3395578508782 6.16307114059918 -0.541865861141678 0.588293993702263 -1.87098810392608 13.1354503085382 -0.142438063406925 0.88682506069437 KIAA1211 other 1 1 1 -0.541865861141678 -0.142438063406925 3.99944135946827e-13 147.489672967705 28.1456362604536 5.24023232599426 2.9163563289494e-07 -175.666649184061 50.8261266294078 -3.45622735458305 0.000621754896633125 LAMTOR3 other 5.31165806950981e-09 1 0.00356349579834327 5.24023232599426 -3.45622735458305 7.87710556984279e-10 371.255574507622 86.8743006445937 4.27347986404453 2.54190157632176e-05 -492.028516155626 157.842634026762 -3.11720923304031 0.00199136886383191 NFKB1 other 9.56595700401708e-06 1 0.277321461976704 4.27347986404453 -3.11720923304031 0.00578950026013862 316.99880948342 214.157133653185 1.48021597074969 0.13980564398022 -1005.44039678232 462.858880959107 -2.17223961372181 0.0305760470281887 AREG other 1 1 1 1.48021597074969 -2.17223961372181 0.000849567508121081 217.050355882624 62.6946611833909 3.46202295037085 0.000608994972024398 -14.1336082774734 113.910447476134 -0.124076488071339 0.90133261445103 MANBA other 1 1 1 3.46202295037085 -0.124076488071339 1.35936964031042e-20 971.14554523313 155.492203590656 6.24562211356741 1.34257630942048e-09 -1457.0174457067 282.515068360463 -5.15730879121703 4.39982599374523e-07 UBE2D3 essential 1.98128125075244e-16 0.00661865824239096 1.78079321681533e-05 6.24562211356741 -5.15730879121703 0.895085033559366 8.59900434666217 20.5861541745523 0.417708148581335 0.676442407873685 -0.761523667720507 37.7189966858561 -0.0201893935319351 0.983904950633463 MAPK10 other 1 1 1 0.417708148581335 -0.0201893935319351 0.00020229344855364 50.2770912746617 27.7969621019621 1.80872611511431 0.0714439292895091 -140.344388480999 49.0937352103578 -2.8587025998256 0.00453640421032513 ELF2 other 1 1 1 1.80872611511431 -2.8587025998256 5.00459995464156e-08 119.514764643102 35.6179227814136 3.35546700397331 0.000889212226853553 -210.068589642168 62.9452698414995 -3.33732129786932 0.000947205166294209 NDUFC1 other 0.000560765424917587 1 1 3.35546700397331 -3.33732129786932 0.0433682874056736 -54.0125556629186 59.7567259076252 -0.903874080156496 0.36675509346113 -265.994757122121 105.653576792375 -2.51761241973701 0.0123126732116931 TBC1D9 other 1 1 1 -0.903874080156496 -2.51761241973701 2.18676086293456e-10 99.986616894803 19.351639986355 5.16682911449905 4.24136414853293e-07 -80.684112847972 34.214892973175 -2.35815768622248 0.0189786438149781 ZNF330 other 2.71092744177997e-06 1 0.00514435057575559 5.16682911449905 -2.35815768622248 5.05456968946781e-05 87.0361113047234 50.1382837912039 1.73592123071418 0.0835587039714331 -286.801133893812 88.6475779305688 -3.23529576993567 0.00134470951088575 INPP4B ts 0.450867616300528 1 1 1.73592123071418 -3.23529576993567 0.000246751763282865 57.8906249550963 30.7612670344033 1.88193239538383 0.0607669882145193 -147.905053450901 54.4350353400215 -2.71709299951825 0.00694994939331195 GAB1 other 1 1 1 1.88193239538383 -2.71709299951825 3.86820495507572e-06 15.3012266885899 26.0871549872768 0.586542560737369 0.5579297288355 -192.736497771624 44.4154588522657 -4.33940125244911 1.92518263054635e-05 KLHL2 other 0.038264283415609 0.281249930496516 1 0.586542560737369 -4.33940125244911 0.758151167644766 -22.0019211630821 266.623160658378 -0.0825206674047085 0.934284929935276 -320.330802431741 453.947163922584 -0.705656578320138 0.480921597763483 CPE other 1 1 1 -0.0825206674047085 -0.705656578320138 0.00303636258114826 413.472893219131 370.162421530512 1.117003966825 0.264835864693277 -1772.20123343087 672.116291251907 -2.63674792070567 0.00878145480527682 RPL34 essential 1 1 1 1.117003966825 -2.63674792070567 0.00673662658526264 117.193162489281 44.2253387609435 2.64990988814715 0.00845253907514556 4.47658943808686 81.9523515150451 0.0546242951584499 0.956471976922607 WFS1 other 1 1 1 2.64990988814715 0.0546242951584499 0.38024341879651 -33.8323716898891 30.5845875587071 -1.10619022162545 0.269480327895715 -63.6816876212555 51.8264709285269 -1.22874829175766 0.22007472122528 ANXA10 other 1 1 1 -1.10619022162545 -1.22874829175766 6.48308898249534e-23 226.317799658803 38.57384900849 5.86713033508765 1.1097623626671e-08 -307.398363743179 71.5721354601395 -4.29494469833693 2.32215425520936e-05 GRPEL1 essential 9.58265382502637e-19 0.338477204239316 0.000143159344784056 5.86713033508765 -4.29494469833693 2.6064742950489e-08 111.412927589813 21.9297160965225 5.08045462601681 6.4319959114982e-07 -55.8257898274701 40.1590944280882 -1.39011575391561 0.165465977888467 GAR1 essential 0.000296694969005417 1 0.00773383188398544 5.08045462601681 -1.39011575391561 1.0289365156288e-10 44.5577487765092 17.5303935273083 2.54174264297596 0.0115383397129236 -156.483021463071 32.2295951861279 -4.85525867015618 1.94682837529705e-06 FRG1 other 1.28565617627819e-06 0.0290583603296838 1 2.54174264297596 -4.85525867015618 3.70938204450852e-07 274.255718725571 100.926741138706 2.71737416299468 0.00693956651980477 -570.722568466099 172.137431700096 -3.31550530776149 0.00102020148372144 CLCN3 other 0.00396199096173955 1 1 2.71737416299468 -3.31550530776149 0.00262777671546383 21.8126404142481 6.34295389016256 3.43887734200273 0.000661715351512874 20.9302793669352 10.8376785867174 1.93125116227263 0.0543377209192107 AADAT other 1 1 1 3.43887734200273 1.93125116227263 0.021587423715461 92.5527419153296 61.1608713948715 1.51326722141978 0.131217639348469 -154.733774297005 104.703967430249 -1.47782150089093 0.140457885514648 GALNT7 other 1 1 1 1.51326722141978 -1.47782150089093 9.85944227242945e-13 364.309879473675 96.1645334142154 3.78840167512134 0.000181502260377671 -633.840512816295 179.396299586952 -3.5331861040371 0.000471826622353886 DHX15 essential 1.29937589708348e-08 1 1 3.78840167512134 -3.5331861040371 0.512891644909207 -30.5258822707978 26.4711057256951 -1.15317745269578 0.249709074428875 -27.9181594959448 49.3822227859184 -0.565348376823284 0.572237998097195 SOD3 other 1 1 1 -1.15317745269578 -0.565348376823284 0.000570252866122765 16.0160254896574 10.3868513313532 1.54195193314381 0.124089234412927 -41.4853086708626 19.390545173761 -2.13946066493271 0.0331666666103398 SEPSECS essential 1 1 1 1.54195193314381 -2.13946066493271 0.351368549862095 46.8434681887155 35.5201362942266 1.31878627381082 0.188183576844241 17.1521036422027 65.872712232807 0.260382532627226 0.794736182605092 CPZ other 1 1 1 1.31878627381082 0.260382532627226 0.718681060272681 3.71206688535553 132.241746708208 0.0280703104560939 0.977623625966277 -163.396130640301 226.17808241044 -0.722422477452038 0.470564035686381 TRIM2 other 1 1 1 0.0280703104560939 -0.722422477452038 5.11354670877395e-09 33.2283359488863 33.8775342078382 0.980836909352106 0.32741413458133 -292.453169417037 63.4883297295431 -4.60640830626467 5.92210025924026e-06 SLC2A9 other 6.01659905754343e-05 0.0877063048393483 1 0.980836909352106 -4.60640830626467 3.12900897596288e-10 53.4879069767447 22.4810426485936 2.37924494040719 0.0179378430473742 -184.811089831281 38.4512494409872 -4.80637411054532 2.37391525892137e-06 FBXW7 ts 3.85744226556704e-06 0.0353927025952587 1 2.37924494040719 -4.80637411054532 0.00126211696842678 2.92723179774798 9.53990799054339 0.306840674003319 0.759166741130949 -52.7083234152399 16.4156963111484 -3.2108490810374 0.00145958486619745 NEIL3 other 1 1 1 0.306840674003319 -3.2108490810374 7.63719852584811e-07 11.8268120055975 4.21302731845598 2.80720040759952 0.00530988730225364 -18.3406024498684 7.87070280994058 -2.33023694233563 0.020426936989586 TBC1D19 other 0.00797247154113285 1 1 2.80720040759952 -2.33023694233563 3.18387909924512e-06 297.133634559891 147.056218022245 2.0205445139011 0.0441595895868197 -759.892763049281 271.979222207687 -2.79393681944209 0.00552093315777961 NSD2 other 0.0316827809165882 1 1 2.0205445139011 -2.79393681944209 1.70736210860687e-11 500.871614917006 98.6904688671296 5.07517717431607 6.59931801547644e-07 -471.220426585486 170.152156162607 -2.76940614337653 0.00594565701065426 SH3D19 other 2.18337466448646e-07 1 0.00792908059559494 5.07517717431607 -2.76940614337653 8.51733331747166e-06 71.8824443186174 45.4920855670117 1.5801087908518 0.115091948255344 -256.799769253493 84.9143988342822 -3.02421936419358 0.00269909720863064 STIM2 other 0.0817999799874676 1 1 1.5801087908518 -3.02421936419358 0.142057039354248 -0.563224477489416 3.33418435045924 -0.168924216026579 0.865963311922444 9.61324563381564 6.23096360831599 1.54281845282896 0.123866226907368 NKX3-2 other 1 1 1 -0.168924216026579 1.54281845282896 3.32114319649239e-18 355.910284509323 102.390285355792 3.47601614032606 0.000579188885592538 -1035.43218448076 189.369960326865 -5.4677742060754 9.19245977670128e-08 MFSD10 other 4.74358882755007e-14 0.00138962414444393 1 3.47601614032606 -5.4677742060754 0.275735604770402 8.9251227684244 6.29390949098187 1.41805705678047 0.157153284889318 -0.795862124747113 10.7897826995932 -0.0737607185339442 0.941247158606904 GLRB other 1 1 1 1.41805705678047 -0.0737607185339442 0.477577248870476 3.44231877899971 3.86068279501947 0.891634708616962 0.373260801513461 8.59923264099982 7.24374808475258 1.18712475094218 0.236061671302469 BST1 other 1 1 1 0.891634708616962 1.18712475094218 1.83031419697328e-05 69.2729297569558 23.1813930948682 2.98829882541835 0.00302451997763234 -82.3015551737881 39.7318091827148 -2.07142732401909 0.0391275425464761 RAPGEF2 other 0.17056698001594 1 1 2.98829882541835 -2.07142732401909 3.33604505466587e-05 43.4966244010941 13.0329839349514 3.33742638049653 0.000945871566854894 -35.2876702014768 24.3701171074757 -1.44798935704138 0.148605219688054 SNX25 other 0.30321313501858 1 1 3.33742638049653 -1.44798935704138 0.00270150704214736 2.53918251527608 1.6434087883768 1.54507054680171 0.12332375312817 -6.59277054005658 3.07297736482225 -2.14540159505468 0.0326777179446697 LRP2BP other 1 1 1 1.54507054680171 -2.14540159505468 2.90843960664592e-15 135.414254768307 24.349564031861 5.56125993020327 5.68313109214651e-08 -162.918775043469 45.5307648604607 -3.57821300702438 0.000399845970180036 UFSP2 other 4.01248328132871e-11 1 0.000714653734837424 5.56125993020327 -3.57821300702438 0.224595892456993 191.668274329583 132.451386828064 1.44708393713075 0.148852296248908 -19.6044396127383 272.326348053281 -0.0719887728560978 0.94265581476219 KLF3 other 1 1 1 1.44708393713075 -0.0719887728560978 0.00093941160052835 205.625549214687 59.7847326782876 3.43943244375106 0.000660157166077843 53.6012389060632 122.920252550878 0.436065154388427 0.663083489512847 KLHL5 other 1 1 1 3.43943244375106 0.436065154388427 0.709428946489882 -0.467174682601558 5.58379558710994 -0.0836661506162617 0.933374679564811 -8.05012540172968 10.3287738571772 -0.779388290715245 0.436332483746547 FAM149A other 1 1 1 -0.0836661506162617 -0.779388290715245 5.49580065969358e-07 21.844262518761 45.5287534206336 0.479790481345821 0.631706207833956 -362.842768262809 85.488921798834 -4.24432500291234 2.88043840975584e-05 NCAPG essential 0.00579422263551495 0.418902157930792 1 0.479790481345821 -4.24432500291234 0.278016392415075 198.913261781434 192.132232565368 1.03529355343206 0.301316016101952 584.122802632148 367.933906655625 1.58757535542618 0.1133730508618 UGDH other 1 1 1 1.03529355343206 1.58757535542618 0.214092302073136 48.3918226334681 29.1987095295471 1.65732744402621 0.0984425779049114 76.7045168265694 54.2969179678517 1.41268638621413 0.158728982459962 PPARGC1A other 1 1 1 1.65732744402621 1.41268638621413 0.0145369823329788 1533.79539357021 523.74934330744 2.92849129678025 0.00365284891321754 1820.24803380978 962.353010810156 1.89145564399222 0.0594749663036476 CRYAB other 1 1 1 2.92849129678025 1.89145564399222 5.31658268861971e-10 278.510825275497 71.9251223804064 3.87223290080029 0.000130766288155903 -483.557211472896 152.609992326913 -3.16858158564771 0.00167974154476326 HTATIP2 other 6.49899067856873e-06 1 1 3.87223290080029 -3.16858158564771 1.84640964887206e-06 1353.2978470437 487.16077472224 2.77792859619147 0.00579558331508687 -2522.23076799486 1213.68296020047 -2.07816279102926 0.0384961405059158 CTSC other 0.0186967441044785 1 1 2.77792859619147 -2.07816279102926 0.00396585551487563 -1.81080545072525 28.1332821134275 -0.0643652398402883 0.948719976328195 -181.6754697241 60.1360715396266 -3.02107312753853 0.00272381233769586 CCDC34 other 1 1 1 -0.0643652398402883 -3.02107312753853 0.0345250160881253 27.6765911570191 11.1390574261761 2.48464390640277 0.0134806200995771 45.1069151837457 20.4142027456582 2.2095849515034 0.0278439704107288 ZBTB16 other 1 1 1 2.48464390640277 2.2095849515034 3.33621803720475e-17 49.0828020604347 10.6441000501849 4.61126838614996 5.80018834511617e-06 -126.934235257243 24.1005104219775 -5.26686916728081 2.55732679956658e-07 ELP4 other 4.71340884296287e-13 0.00385465868498671 0.0661453478877048 4.61126838614996 -5.26686916728081 6.36037110713264e-32 245.217589779643 35.4392201950537 6.91938446811166 2.48100172610567e-11 -295.764349938849 66.0618516158764 -4.47708235092474 1.05379536860276e-05 ZPR1 other 9.63723430152737e-28 0.155034374628839 3.4069115702883e-07 6.91938446811166 -4.47708235092474 3.67525282857666e-22 427.941705824985 54.3304621180703 7.87664395150896 5.32944372391454e-14 -425.627412827884 142.78011021003 -2.98099932968105 0.003094086362095 MTCH2 other 5.40813453725056e-18 1 7.61044563774996e-10 7.87664395150896 -2.98099932968105 2.89778626630037e-07 136.71374530839 40.936911952696 3.3396203765044 0.000938361421724798 -271.681629154898 107.581945236578 -2.5253459449674 0.0120425858058371 FNBP4 essential 0.00311512023627289 1 1 3.3396203765044 -2.5253459449674 5.85869901528074e-06 167.269174607661 110.679479216451 1.51129347365775 0.131700553811362 -575.802073535611 207.85962483839 -2.77014871927771 0.00593035642190574 SC5D other 0.0570930219039108 1 1 1.51129347365775 -2.77014871927771 0.00298108378058574 -8.4112502717025 5.04189187086713 -1.66827264192318 0.0962397549591653 12.3442495829309 9.47135684321498 1.30332430582784 0.193401014366686 CRTAM other 1 1 1 -1.66827264192318 1.30332430582784 0.000170379960549264 631.083867337652 1135.13073808941 0.555956989060006 0.578628766615436 -6219.54974288 2132.3797811431 -2.91671764939822 0.00378737603977949 HSPA8 other 1 1 1 0.555956989060006 -2.91671764939822 0.461629599408837 -42.7011732155949 45.7932260926534 -0.932477941807325 0.35179259160559 -104.99495214041 85.5057328124687 -1.22792880298079 0.220376131696747 VWA5A other 1 1 1 -0.932477941807325 -1.22792880298079 0.00016658764494218 101.363178267819 24.5770912529359 4.12429515049753 4.76637177420495e-05 17.4354277178061 96.9658419694984 0.179809996630469 0.857417715905604 DNAJC4 other 1 1 0.509763461251219 4.12429515049753 0.179809996630469 4.11204371932827e-17 154.973530368898 32.9646905236403 4.70119779397778 3.85428907033707e-06 -194.460748303192 61.0425591856073 -3.18565851264378 0.00158703138338914 SIAE other 5.80291609671605e-13 1 0.0444399529809864 4.70119779397778 -3.18565851264378 3.41787060299554e-15 111.369846829365 15.4016281251891 7.23104375226547 3.65761770462541e-12 -181.271350865249 64.3855189709497 -2.81540560303687 0.00517847997080835 SNX15 other 4.70982569092785e-11 1 5.09396417723181e-08 7.23104375226547 -2.81540560303687 0.203651849111889 38.0533270410571 22.1595588562739 1.71724208445979 0.0869116327255966 1.69041017775645 78.5330117797238 0.0215248357276537 0.982840534204198 LPXN other 1 1 1 1.71724208445979 0.0215248357276537 0.0119080080195544 104.219772141208 36.9911562404774 2.81742402058701 0.00514392428917928 -19.0535069795267 130.215304267409 -0.146323099936077 0.883759044495907 DTX4 other 1 1 1 2.81742402058701 -0.146323099936077 7.42376691682021e-09 168.004063190624 32.4480715720725 5.1776285939662 4.01432847628457e-07 -305.99102530028 135.647082944276 -2.25578772988419 0.0247696462771651 ATG2A other 8.66873262877096e-05 1 0.00487339477020947 5.1776285939662 -2.25578772988419 6.3477436553185e-11 657.87842288052 95.5824444207473 6.88283739621248 3.17948375050793e-11 -42.8870585238085 393.918478479674 -0.108872928960659 0.913372598553551 EHD1 other 7.99815700570131e-07 1 4.36002606707152e-07 6.88283739621248 -0.108872928960659 1.93400143053054e-17 305.911557484548 44.6416200191758 6.85260878420506 3.76829839149252e-11 -664.418111334242 161.018237009583 -4.12635316144157 4.71185284509955e-05 OSBP other 2.74144702777704e-13 0.680344432303923 5.16030781730985e-07 6.85260878420506 -4.12635316144157 0.00849418074993572 103.629251761349 34.0473301408936 3.04368217221478 0.00254119814953302 21.0197342370464 166.770553204557 0.126039842365121 0.899783702395158 UNC93B1 other 1 1 1 3.04368217221478 0.126039842365121 1.36529461731145e-22 50.1002222523812 9.10461891231827 5.50272589494076 7.68911131609634e-08 -64.0962719096632 16.859531516579 -3.80178250188229 0.000172093008647207 PUS3 other 2.01408261945784e-18 1 0.000962138498983135 5.50272589494076 -3.80178250188229 2.54345016659257e-14 98.5029010827201 18.0137739391788 5.46819902455214 9.19138965740344e-08 -46.2343303553167 33.4086956691888 -1.38390109009722 0.167356238304403 DCPS other 3.45629443138264e-10 1 0.00114635011807136 5.46819902455214 -1.38390109009722 1.7977349287545e-21 256.038554216867 25.8088434988494 9.92057448169971 3.0755219569671e-20 -145.099294506548 124.198832037799 -1.16828227871247 0.243623590718213 KMT5B other 2.63440076459684e-17 1 4.57299359781439e-16 9.92057448169971 -1.16828227871247 1.8101738388656e-11 83.4440131936449 24.1508731965909 3.45511371429103 0.000624476989835969 -125.393917659501 44.7906793709247 -2.7995538228183 0.00542906449628031 FOXRED1 other 2.31358318345412e-07 1 1 3.45511371429103 -2.7995538228183 9.40012801760804e-11 144.744387854318 27.083372831689 5.34440037265077 1.8346713641123e-07 -907.075086395773 246.893957045551 -3.6739460829672 0.000284220287986143 PPP6R3 other 1.17642602140365e-06 1 0.00225994818631353 5.34440037265077 -3.6739460829672 0.504558791617324 18.3450449713387 15.6692007926335 1.17077094193363 0.242567438880688 20.2133804182152 63.535087348073 0.318145158241107 0.750583657434436 NRXN2 other 1 1 1 1.17077094193363 0.318145158241107 0.0975367195689735 -64.7117752316083 33.5074902263151 -1.93126297417486 0.0543334841635232 35.3784856705822 113.618816469119 0.311378755473992 0.755715457183285 MS4A6A other 1 1 1 -1.93126297417486 0.311378755473992 0.854198910340294 -4.27424745302894 12.6585756805999 -0.337656270411173 0.735843618786677 13.622260382695 42.9233099017665 0.317362766614939 0.751175326034766 MS4A4A other 1 1 1 -0.337656270411173 0.317362766614939 4.96788544300212e-06 133.269611036774 40.5801460600784 3.28410870772791 0.00113671125199417 -65.8880534114743 75.2607285130723 -0.875463933358418 0.381980226156435 ST3GAL4 other 0.0487200525395218 1 1 3.28410870772791 -0.875463933358418 1.63815539986718e-14 226.321292152171 29.0159226107641 7.79989990972103 1.17656159139022e-13 -763.296483139133 377.987319198654 -2.01937060946211 0.0443845968932093 CPT1A other 2.23280581001897e-10 1 1.6724823021612e-09 7.79989990972103 -2.01937060946211 4.62883204303997e-36 1513.8923264445 102.373322552292 14.7879573379207 3.19421233623045e-36 -939.439380992553 1498.64772880409 -0.626858042044491 0.531308743358144 CCND1 og 7.04924831834557e-32 1 4.87468744632129e-32 14.7879573379207 -0.626858042044491 5.02676920170604e-40 545.694842202886 36.7613950071295 14.8442365176037 2.73946535079234e-38 -184.931025128457 168.285837612739 -1.0989102098658 0.272633323395427 CCDC86 essential 7.6778872786858e-36 1 4.18535516294053e-34 14.8442365176037 -1.0989102098658 1.97803635398291e-37 1205.22888284109 86.0676808239466 14.0032689541899 4.41269274695957e-35 -653.622863795008 395.311601621348 -1.65343708890458 0.0992225760614384 PRPF19 essential 3.01571422528234e-33 1 6.72935643911335e-31 14.0032689541899 -1.65343708890458 5.43805213809944e-09 428.367879680188 81.4463839928502 5.25950765006084 2.6485516674877e-07 -855.771336407506 379.160298262107 -2.25701725716 0.0246810792600373 TMEM109 other 6.39188648312208e-05 1 0.00324341637200544 5.25950765006084 -2.25701725716 8.59103820873834e-09 40.6719389712402 8.34528968486007 4.8736401619499 1.72740706588131e-06 -18.6629005850895 16.6483338905207 -1.1210071054447 0.263125388202554 TRIM3 other 0.000100077004093593 1 0.0203212167230278 4.8736401619499 -1.1210071054447 5.47714551756794e-20 159.841352361161 26.6722074405916 5.99280553426948 5.58655196039024e-09 -207.94993699151 65.6158041526043 -3.16920503645548 0.00167720642980081 CHORDC1 essential 7.9445995732323e-16 1 7.28151182517263e-05 5.99280553426948 -3.16920503645548 0.0008733197341217 72.3067125468646 20.0842150459041 3.60017617724176 0.00037215032601479 25.2416879904856 82.376719998316 0.30641773538691 0.759499868182125 FOLR1 other 1 1 1 3.60017617724176 0.30641773538691 1.38677644987161e-18 220.538273371334 24.6334367873996 8.95280164415153 3.97780776268719e-17 -2.63507105649056 102.063892001851 -0.0258178578614536 0.979420073811356 ANAPC15 essential 1.98822139618092e-14 1 5.81396382594359e-13 8.95280164415153 -0.0258178578614536 0.00632750277166619 13.6491357625828 7.69953794030776 1.77272141112889 0.0773067999665305 -56.4344988842572 31.9015497344529 -1.76902060727505 0.0779236735601807 FOLR3 other 1 1 1 1.77272141112889 -1.76902060727505 6.48048902614911e-20 294.061083019988 47.9960381037017 6.12677826416903 2.69086145198098e-09 -325.323464584174 113.40108453976 -2.86878618405199 0.00440057546222887 PANX1 other 9.39735713681882e-16 1 3.54036641237137e-05 6.12677826416903 -2.86878618405199 1.3598569486199e-12 153.724655700632 23.6819891506699 6.49120539337311 3.37467712689343e-10 -91.0431840680397 84.2594022284256 -1.08051068082851 0.280754719262456 ARHGEF17 other 1.78671604479168e-08 1 4.5379283325336e-06 6.49120539337311 -1.08051068082851 8.96537803631873e-25 194.664735259733 30.0972418029039 6.46785963094304 3.71876537356447e-10 -175.500951400651 55.6079779119147 -3.15603907911651 0.0017513641249564 CEP164 other 1.33503444338822e-20 1 4.99727690899594e-06 6.46785963094304 -3.15603907911651 2.18978276450864e-15 26.7984312311741 67.2367247565518 0.398568361683363 0.690480452230152 -1036.11368331673 139.115724592116 -7.44785455673395 9.11445644128021e-13 RNF141 other 3.02934547642125e-11 1.39697273875502e-08 1 0.398568361683363 -7.44785455673395 4.5145030446462e-11 8.06801760929827 1.18334181312916 6.8179941921968 4.87922250244223e-11 -9.3348128136927 12.2554224284608 -0.761688376568273 0.446828844943066 CEP126 other 5.71220070239083e-07 1 6.6640420938356e-07 6.8179941921968 -0.761688376568273 1.26017968116097e-19 3090.68141592922 700.623858046793 4.41132767665871 1.40946859150438e-05 -8520.34679203541 1451.7090757852 -5.86918338815713 1.10339274068136e-08 EIF4G2 essential 1.82461416035297e-15 0.000167660526946533 0.156493297714731 4.41132767665871 -5.86918338815713 0.000766585627591644 -63.2171237385797 38.2271319380542 -1.65372395295103 0.09916420470549 117.31595757634 72.1374019751335 1.62628476163835 0.104873414031684 IL10RA other 1 1 1 -1.65372395295103 1.62628476163835 6.60608267680168e-08 244.37323578786 64.1325027301684 3.81044283919556 0.000166614647699285 -292.100150255954 132.884050688417 -2.1981580840041 0.0286604261756675 GALNT18 other 0.000735323062754794 1 1 3.81044283919556 -2.1981580840041 6.38921202250711e-52 373.264986669233 20.5604975309355 18.1544724833441 9.00188246371298e-51 -231.755013316101 265.719415757149 -0.872179447842498 0.383781174108813 BIRC2 other 9.79657879411016e-48 1 1.38016861933647e-46 18.1544724833441 -0.872179447842498 1.15261007702084e-33 343.538157558568 39.9325376754864 8.60296333657396 3.57830267669734e-16 -227.827294489228 75.5045432212598 -3.01739848715592 0.00275478421039992 UBE4A other 1.75012314094844e-29 1 5.19784246817055e-12 8.60296333657396 -3.01739848715592 6.34630641366178e-18 634.101721630606 114.036196488014 5.56053026283858 5.69218594567054e-08 -519.375259422527 215.619928702976 -2.40875350690791 0.016573661110381 DDX6 essential 9.04285200882667e-14 1 0.000715735460808614 5.56053026283858 -2.40875350690791 7.3135725239367e-13 18.3636578436782 3.07226181504788 5.97724378623375 6.070222127315e-09 -0.583297771697056 5.80904040926278 -0.100412069912091 0.920080264750545 UPK2 other 9.66269201862517e-09 1 7.90282218755139e-05 5.97724378623375 -0.100412069912091 3.82851516361713e-18 381.091429940393 51.4180115522211 7.41163297521433 1.12924493095597e-12 2.19350800478762 96.999529458901 0.0226135942826096 0.981972638291652 CBL other 5.46520539606346e-14 1 1.58444356262432e-08 7.41163297521433 0.0226135942826096 2.95464181853785e-21 2915.62094838835 565.628036088325 5.15466130100572 4.46505615308587e-07 -4073.46802816297 1067.05124708308 -3.8174998991832 0.000161943933842114 NECTIN1 other 4.32411830143014e-17 1 0.00540896902384822 5.15466130100572 -3.8174998991832 4.55460566694937e-07 307.383027189317 83.3867149262944 3.68623500111514 0.000267247793016816 -578.446771960034 230.058515426617 -2.51434627789096 0.0124155359318748 HIPK3 other 0.00482833746753303 1 1 3.68623500111514 -2.51434627789096 0.000368239505357464 160.621729009935 46.6802381176982 3.44089352339952 0.000656980927230384 -93.2264398828153 133.160880131422 -0.700103812702397 0.484372731036979 KIAA1549L other 1 1 1 3.44089352339952 -0.700103812702397 4.23071177673434e-23 237.855079749944 30.2759324082287 7.85624292400973 6.15586142054706e-14 -299.377904548999 75.5052013565374 -3.96499710179341 9.07058767171321e-05 FBXO3 other 6.25806886014543e-19 1 8.78195190255243e-10 7.85624292400973 -3.96499710179341 2.67391542805138e-12 162.6389522481 26.2840519943878 6.18774275301338 1.88386047476035e-09 -112.793619990245 69.2300595161703 -1.62925787986502 0.104251722392794 PDHX other 3.486785718179e-08 1 2.48857968715842e-05 6.18774275301338 -1.62925787986502 0.73049441085701 1.38899824234232 6.86032571839269 0.202468264534203 0.839680958130083 -11.2413575615524 18.0129384130757 -0.624071281640101 0.533031032433362 SLC1A2 other 1 1 1 0.202468264534203 -0.624071281640101 2.67545933673206e-25 224.384260540943 22.7472314287584 9.86424485299179 3.60001843340481e-20 -110.273287955982 58.9486675148089 -1.8706663374245 0.0623213766020341 COMMD9 other 3.99365815193995e-21 1 5.35214740494294e-16 9.86424485299179 -1.8706663374245 5.8968541086273e-07 320.368807979777 59.1212664967256 5.41884210138699 1.18209049145064e-07 129.497702446976 275.229371024008 0.470508296280923 0.638312439861477 SLC15A3 other 0.00620113178063247 1 0.00146732892703768 5.41884210138699 0.470508296280923 0.0855288018188709 -22.443494777921 12.1171176145129 -1.85221399114258 0.0649158889130975 43.611249651029 56.4942728648365 0.771958774571179 0.440708556270741 CD5 other 1 1 1 -1.85221399114258 0.771958774571179 0.108657819162737 16.9049296562213 12.8663566384027 1.31388629518977 0.189855927202634 -26.1393992261066 30.5647094919734 -0.855215039193194 0.393092589154577 ACCS other 1 1 1 1.31388629518977 -0.855215039193194 0.00111149515925208 499.251760445311 359.964120571233 1.38694867603204 0.166447462166624 4918.00869827646 1325.4205983885 3.71052683522194 0.00024482532627117 SCGB2A2 other 1 1 1 1.38694867603204 3.71052683522194 0.208136383298585 448.830935310399 386.734588775423 1.16056579457142 0.246700114446667 -621.579981916401 953.847006247439 -0.651655850304316 0.515099878006045 MDK other 1 1 1 1.16056579457142 -0.651655850304316 3.74065073363941e-22 171.585645318123 27.4086680541251 6.26026937825967 1.26065995433243e-09 -325.25838313649 67.0994221273506 -4.84740960241312 1.97018630393315e-06 AMBRA1 other 5.5032453593303e-18 0.0294010902135944 1.67352608937629e-05 6.26026937825967 -4.84740960241312 2.43687507365744e-09 106.951589573589 38.1734368787798 2.801728068479 0.0053944898360399 -379.359621398261 96.7982170728904 -3.91907653745934 0.000108870168697881 MADD other 2.9059735253365e-05 1 1 2.801728068479 -3.91907653745934 6.62553551795446e-17 197.891428022579 29.6703061112889 6.66967935148083 1.13166434901414e-10 -202.261294958182 77.9733764702536 -2.59397892093775 0.00992486197660706 PTPMT1 essential 9.3267663486245e-13 1 1.5363475202216e-06 6.66967935148083 -2.59397892093775 0.000280696594599936 55.4510331454273 19.1736046851344 2.89205050672706 0.00409369980696191 -156.695021375277 77.2970010287123 -2.02718112332808 0.0434857083925833 NAA40 other 1 1 1 2.89205050672706 -2.02718112332808 2.59674023053758e-08 77.3568867179121 69.5009589410629 1.11303337243895 0.266529489832391 -587.175646780917 133.071035053845 -4.41249778017676 1.3983121964326e-05 CARS other 0.000295638875246703 0.205146382338627 1 1.11303337243895 -4.41249778017676 0.113029251753391 -0.545305735974535 32.9590448239988 -0.0165449496150895 0.986809952995235 -106.348641310467 61.069350079565 -1.74144052903641 0.0825673697830069 SLC22A18 other 1 1 1 -0.0165449496150895 -1.74144052903641 0.0134842684978784 1000.35487388653 396.48221662292 2.52307627415716 0.0121174959803464 122.801282796366 732.306247899364 0.167691158103081 0.866932178903594 CD81 other 1 1 1 2.52307627415716 0.167691158103081 4.2063756103291e-32 344.697140390254 36.1816159324624 9.52685864096495 4.44409538182287e-19 -101.111856270096 68.4876215407883 -1.47635228082608 0.140845140022038 SLC35F2 other 6.37518287501479e-28 1 6.57015061248694e-15 9.52685864096495 -1.47635228082608 0.00217513927366036 -6.7871800778361 1.98449178810964 -3.42010993368803 0.000707076175983446 -4.44081424812986 3.62664825464544 -1.22449543940236 0.221666060277127 C11orf21 other 1 1 1 -3.42010993368803 -1.22449543940236 6.88370779908588e-22 510.438610075943 76.8539358345748 6.64167169232091 1.33762287488314e-10 -736.122876535603 160.795625994337 -4.57800311409918 6.73605729188942e-06 C11orf58 other 1.01121667568572e-17 0.0996195512897526 1.8131478069041e-06 6.64167169232091 -4.57800311409918 5.77771649769875e-10 283.62601686453 46.6198497323578 6.08380375511317 3.47777043225902e-09 -358.65096715722 240.943522413802 -1.48852711857207 0.137635082075799 PITPNM1 other 7.05054744214179e-06 1 4.55970481373479e-05 6.08380375511317 -1.48852711857207 1.67200236852703e-06 1047.61624549531 301.634703357549 3.47312903268128 0.000585455504509257 -1259.86210094586 625.514642647451 -2.01412087751227 0.0448359720970891 RPS13 essential 0.0170059360902884 1 1 3.47312903268128 -2.01412087751227 2.77166677932211e-07 218.205178309722 39.3051611296952 5.55156554605413 6.11586680790208e-08 51.5744992672203 207.010204710311 0.249139888245575 0.803418634597757 AIP other 0.00298425362129611 1 0.000767969395068264 5.55156554605413 0.249139888245575 4.38574179476249e-18 493.528288574777 99.2558148923117 4.97228589690422 1.08105784368795e-06 -901.969121067699 197.346707521509 -4.57047970242621 6.95951131236159e-06 NUP98 essential 6.2577586446714e-14 0.102868536708017 0.0128689125712613 4.97228589690422 -4.57047970242621 0.51198520985513 77.9831995199861 67.3357306675485 1.15812509564954 0.247728033760808 86.1997194205546 324.627266526872 0.265534439983399 0.790778951155186 TCIRG1 other 1 1 1 1.15812509564954 0.265534439983399 0.17639469720831 27.640185754557 17.0136670375524 1.62458720354347 0.10529371709336 -40.0006322471615 82.2674703715567 -0.486226598028367 0.627159144937776 CHKA other 1 1 1 1.62458720354347 -0.486226598028367 1.61222182333051e-07 89.772598300006 33.7732262794099 2.6580995714566 0.00825807473365983 -139.648764752645 62.0132383996264 -2.25191859603781 0.0250137563836941 EXPH5 other 0.00175828912052426 1 1 2.6580995714566 -2.25191859603781 2.49933753688321e-09 66.8165849618527 28.5279785926834 2.34214228480209 0.0197881069152341 -260.28976152233 59.686912925804 -4.3609184788279 1.75016084430221e-05 HPS5 other 2.97846054270372e-05 0.256066033129856 1 2.34214228480209 -4.3609184788279 1.10333407436364e-20 171.399308158213 31.5493219099921 5.43274142776197 1.10302078708133e-07 -356.531848703877 66.0082390202301 -5.40132344076938 1.29547811490656e-07 GTF2H1 essential 1.60921274745937e-16 0.00195681969256636 0.0013711651404208 5.43274142776197 -5.40132344076938 0.0136993513195799 -261.619381229301 102.776392430126 -2.545520182635 0.0113847803051572 -87.910250774609 187.418525609032 -0.46905849082388 0.639350254593685 POU2AF1 og 1 1 1 -2.545520182635 -0.46905849082388 0.728390804949345 28.4223591318618 118.460844645813 0.239930410903636 0.810537823860824 -467.309998034617 655.025633900491 -0.713422458372993 0.476104345734588 VWF other 1 1 1 0.239930410903636 -0.713422458372993 0.533279293872766 51.4933400478407 47.4325859367499 1.08561106317302 0.278468244044046 55.2595181847131 124.843604055235 0.442629949711037 0.658332458129586 PSMD9 other 1 1 1 1.08561106317302 0.442629949711037 0.00107159056981117 177.885289209447 47.6283156600759 3.73486416103851 0.000222418778639327 175.616112383915 267.467221963623 0.656589286323092 0.511918403219806 P3H3 other 1 1 1 3.73486416103851 0.656589286323092 8.22184239579921e-18 385.13730486151 42.6662085584848 9.02675250212547 1.68873267606624e-17 -257.526222186912 219.34329451913 -1.17407839045862 0.241236658601603 PPFIBP1 other 1.17005039134619e-13 1 2.47314900409902e-13 9.02675250212547 -1.17407839045862 0.00129646878918149 85.6979523239984 27.7229500895095 3.09122773901421 0.00216908100435908 -98.2956998116604 74.4873691455979 -1.31962909872042 0.187905159468262 PRPF40B other 1 1 1 3.09122773901421 -1.31962909872042 2.8345536748361e-18 73.7410132934136 7.68803529361463 9.59165904904987 2.65218305399507e-19 65.4813570152894 40.0914960437782 1.63329791793718 0.103396018504726 CD69 other 4.05284484428065e-14 1 3.9239048283857e-15 9.59165904904987 1.63329791793718 2.43733034962791e-08 160.91244150905 29.4173559213435 5.46998316025751 9.0883147826484e-08 -147.988260706846 80.2798238298999 -1.84340539934927 0.0661944039597742 PRDM4 other 0.000277782539947093 1 0.00113385815228321 5.46998316025751 -1.84340539934927 0.450678487371113 50.9572637680044 41.0775417473359 1.24051395483785 0.215699820680289 96.8767548868139 208.967672514759 0.463596850751982 0.643253762673895 CLEC2B other 1 1 1 1.24051395483785 0.463596850751982 0.342485856572613 27.522761083011 19.6541731154324 1.40035202302152 0.162379808327627 -12.7051472775961 53.8726831807996 -0.235836541405538 0.813710851308372 COQ5 other 1 1 1 1.40035202302152 -0.235836541405538 0.0782590183971375 -67.5271332842702 31.0115016298767 -2.17748673025282 0.0301744631004633 26.0551187202231 86.9712035687355 0.299583283329305 0.764689529446916 SELPLG other 1 1 1 -2.17748673025282 0.299583283329305 2.48012600788798e-07 1004.54457915327 201.589380540729 4.98312250605044 1.02634293500041e-06 -1071.47228570322 565.353824576237 -1.89522426332987 0.0589637525086878 CORO1C other 0.00267754403811586 1 0.0122288760705298 4.98312250605044 -1.89522426332987 0.387902915802288 18.3233460678236 13.3783806169313 1.36962361832 0.171767764082501 4.77057943894396 36.4820055508146 0.130765273644268 0.896043419732187 ASIC1 other 1 1 1 1.36962361832 0.130765273644268 0.000339740861902155 43.8529714025362 11.3869089383196 3.85117433010823 0.000142237423734118 -44.0853204317508 64.8664412551476 -0.679632173103874 0.497233365167078 CAPRIN2 other 1 1 1 3.85117433010823 -0.679632173103874 0.94681639843391 4.33431512634328 31.1633649412655 0.139083668740917 0.889472629353487 -49.1561691519851 177.539240406636 -0.276874954739008 0.782057144035963 TSPAN11 other 1 1 1 0.139083668740917 -0.276874954739008 1.47572951595374e-10 328.34015984016 51.2941639030271 6.40112119696297 5.48687861412551e-10 -258.812271062271 143.851604240697 -1.79916152084907 0.0729351858297006 KCTD10 essential 1.83580751784645e-06 1 7.34747915217547e-06 6.40112119696297 -1.79916152084907 0.0447441747658108 155.27872978763 62.30183503703 2.49236205796086 0.0131967543572576 45.4608585293198 169.893199836934 0.267584921426837 0.789191763103588 SLC11A2 other 1 1 1 2.49236205796086 0.267584921426837 9.99342839291402e-05 572.514965676581 137.06804509397 4.17686679111882 3.8188323765016e-05 -239.89490889874 375.707658836126 -0.638514821981249 0.523596747863462 MLEC other 0.861433527469188 1 0.411631941863107 4.17686679111882 -0.638514821981249 0.182570767785063 3.17260065515877 34.5080781088285 0.0919379121941624 0.926804896657099 -175.497668029645 96.775968599525 -1.8134426404543 0.0707002564401659 MVK essential 1 1 1 0.0919379121941624 -1.8134426404543 2.30045765968352e-06 99.2532340970102 22.7833567042681 4.35639205343331 1.78464622580205e-05 -117.095903437841 62.1287859533148 -1.8847286590443 0.0603753893267393 CSRNP2 other 0.0231403035987565 1 0.196792939319192 4.35639205343331 -1.8847286590443 4.30228659134613e-05 164.814847454782 41.6488557344171 3.95724791350234 9.34355419567438e-05 -180.508061111893 109.620699609224 -1.64666036392186 0.100609539439537 CAMKK2 other 0.386732541696104 1 0.971636200808179 3.95724791350234 -1.64666036392186 0.153909444572049 -25.3662631066658 13.6056434243462 -1.86439276082122 0.0631848585908169 5.29097210274634 37.1017369846109 0.142607126586578 0.886690498302837 BIN2 other 1 1 1 -1.86439276082122 0.142607126586578 0.905160642469794 -5.34315246349443 11.9986442780836 -0.445313015342415 0.656394656203972 -4.02125176445646 34.2811871091247 -0.117301998663463 0.90669432989182 IL23A other 1 1 1 -0.445313015342415 -0.117301998663463 0.0189231360925394 1444.49873537248 579.746994363363 2.49160193915058 0.013222875143338 -1403.19803103516 1656.38839931484 -0.84714311668422 0.397548475469394 ATP5B essential 1 1 1 2.49160193915058 -0.84714311668422 0.010381675479905 519.068357333153 206.363578718872 2.51530992317339 0.0123823200673907 -707.103381493561 589.598982236027 -1.19929545809578 0.231300348344132 PTGES3 other 1 1 1 2.51530992317339 -1.19929545809578 0.288078443440624 35.1765641008201 29.8646053694028 1.17786803695252 0.239724440465881 -66.197970396547 77.9727423989626 -0.848988612685089 0.396522289917022 BCL7A other 1 1 1 1.17786803695252 -0.848988612685089 0.385141554892538 61.3152145539054 47.7269856112703 1.28470746200712 0.199823715598895 -37.1259016082501 124.609178943287 -0.297938738727642 0.765943266219067 RSRC2 essential 1 1 1 1.28470746200712 -0.297938738727642 0.671295140959143 20.96794336434 27.2170765090945 0.770396605871086 0.441633051384499 -26.7130682662299 89.1753253531875 -0.299556723347296 0.76470977283125 CYP27B1 other 1 1 1 0.770396605871086 -0.299556723347296 0.013173158983517 49.8061869290475 31.4804803264465 1.58212919283845 0.114614115386099 203.983276690801 73.6750385378377 2.76868910745177 0.00595844253890678 MYF6 other 1 1 1 1.58212919283845 2.76868910745177 0.938112451318914 -2.13427264492593 6.06757361972004 -0.351750597304562 0.725258277409288 -0.0939213071545453 14.1951326991088 -0.00661644446342103 0.994725028367986 LIN7A other 1 1 1 -0.351750597304562 -0.00661644446342103 0.146089088906387 284.718920262028 400.658044697683 0.710628237795308 0.477832233051489 -1780.60786311272 1082.6199896184 -1.64472102878902 0.101009299111124 KRT18 other 1 1 1 0.710628237795308 -1.64472102878902 0.792604529707547 4.77606215868995 7.03508124677439 0.678892253146299 0.497699918694268 1.13764496363139 16.4586238430482 0.069121511888244 0.944936341662761 ACSS3 other 1 1 1 0.678892253146299 0.069121511888244 0.124489953904979 73.1561870341089 39.5521184411716 1.84961488580994 0.0652909873071671 -50.4464287327763 106.873965524582 -0.47201793706413 0.63723569097007 TNS2 other 1 1 1 1.84961488580994 -0.47201793706413 0.00119494637903379 66.7714985808302 19.5373189395226 3.41763876545805 0.000713296339501047 -49.1999596649938 64.4561631587971 -0.763308848275418 0.44584159157757 GLI1 og 1 1 1 3.41763876545805 -0.763308848275418 0.18833028254432 -24.4666540239533 25.1776430544783 -0.971761096581334 0.331907978870915 -141.431241456933 84.5982327762402 -1.67179900590848 0.0955476046581513 PPM1H other 1 1 1 -0.971761096581334 -1.67179900590848 1.08495864530709e-05 271.281745286285 65.2295201702353 4.15887997609513 4.1122838034144e-05 -283.693188367783 158.751302157938 -1.78702904802346 0.0748791997523153 METAP2 essential 0.103157867995798 1 0.441947140352945 4.15887997609513 -1.78702904802346 0.368414409941953 133.401993256939 98.8997158255239 1.34886123932128 0.178335278632022 -46.5604214733425 240.695602686897 -0.193441097193244 0.846736257216732 LTA4H other 1 1 1 1.34886123932128 -0.193441097193244 0.0381163362323872 209.292640966573 101.972954546458 2.05243284258495 0.04094068913332 -291.463769565727 248.175048304728 -1.17442817703352 0.241096797966371 ELK3 other 1 1 1 2.05243284258495 -1.17442817703352 0.343250487037031 1.9063333010456 1.3013161303634 1.46492712767131 0.143967461452428 1.49826663159829 6.2492244784013 0.239752410363338 0.810682721065391 SLC6A12 other 1 1 1 1.46492712767131 0.239752410363338 0.00204561169637521 77.0897733107214 24.8637435529292 3.10048939921758 0.00210827953087345 -150.88227560562 121.564904635988 -1.24116640454265 0.215476648109857 WNT5B other 1 1 1 3.10048939921758 -1.24116640454265 6.33765125997455e-27 104.545750078577 8.72145150126751 11.9871961752448 1.34152568903905e-27 23.7077457792644 45.6961900523024 0.518812306936952 0.604250223030109 MAGOHB other 9.50711065508782e-23 1 2.03080158806731e-23 11.9871961752448 0.518812306936952 0.654466310298671 9.01455521222962 52.6698925520736 0.171151957511915 0.864212454692982 -128.58228980322 147.709758036504 -0.870506400609249 0.38467626819762 TRPV4 other 1 1 1 0.171151957511915 -0.870506400609249 4.24541747513624e-14 705.037889907277 86.2265073534902 8.17657947128644 7.29682641353127e-15 72.1366071862234 422.099005759561 0.170899732531743 0.864412678522597 FOXM1 other 5.73895534288916e-10 1 1.04979441611474e-10 8.17657947128644 0.170899732531743 0.733528716080322 -1429.70666786403 2162.77313718879 -0.66105253633878 0.509054265684722 -6132.90344758881 11331.8857878909 -0.541207665024504 0.58874101852625 PRR4 other 1 1 1 -0.66105253633878 -0.541207665024504 0.0644171410987078 6.92575369339079 2.95452134799821 2.34412037607487 0.0196950998460837 2.36812246266331 14.4630759352561 0.163735741502306 0.870044517641618 PRMT8 other 1 1 1 2.34412037607487 0.163735741502306 4.00910257852957e-07 34.7943003337339 6.97421537025305 4.9889913755949 1.00535830950387e-06 -55.2845759384731 33.7357927868621 -1.63875134898276 0.102263422643004 PARP11 other 0.00426568514355546 1 0.0119868871242147 4.9889913755949 -1.63875134898276 0.0197028592011926 260.811002950538 98.8227748352776 2.63917911013195 0.00871750542337934 -164.993930488116 277.142926482771 -0.595338775490536 0.552037822738729 ARPC3 essential 1 1 1 2.63917911013195 -0.595338775490536 0.20152806961398 30.5060520874475 17.9222579806855 1.70213218224642 0.0897017760046896 -15.6940327114746 50.2619667806904 -0.312244699455412 0.755057927568976 GPN3 essential 1 1 1 1.70213218224642 -0.312244699455412 0.552062821344874 16.0449957019726 45.6309509030726 0.351625275924115 0.725350727169177 -124.148277110486 127.96944117941 -0.970140026918094 0.332709394404978 VPS29 essential 1 1 1 0.351625275924115 -0.970140026918094 0.0146193952284451 50.8124549868735 493.749160304768 0.102911476255492 0.91809769045828 4026.7010392708 1384.69181282719 2.9080124558903 0.00389157901172823 MYL2 other 1 1 1 0.102911476255492 2.9080124558903 5.13800450831386e-08 87.415661882873 15.1125235244203 5.78431932573127 1.75072598011446e-08 -35.43363512848 74.2834483331289 -0.477005792320997 0.633687707655683 RAD51AP1 other 0.00057540512488607 1 0.000224583128729083 5.78431932573127 -0.477005792320997 0.717650659698192 21.0122609948191 41.6221395574024 0.504833754781886 0.614023077468322 -65.2403420223185 116.726954719095 -0.55891411010696 0.57661125228086 SH2B3 other 1 1 1 0.504833754781886 -0.55891411010696 0.00497724983319002 4.85250880090398 1.49241384683789 3.2514498650528 0.0012721298592803 7.05502792385587 7.31349891453026 0.964658367534469 0.335453596725789 AKAP3 other 1 1 1 3.2514498650528 0.964658367534469 0.109750857871815 44.9895538602964 42.6894807727983 1.05387915350246 0.292735820328547 -304.944001093995 192.664722873649 -1.58277029933487 0.114464720226023 MANSC1 other 1 1 1 1.05387915350246 -1.58277029933487 4.34233665172527e-12 248.173490352995 35.846926969259 6.92314547815549 2.43618981304344e-11 -246.262871864332 159.741988265549 -1.54162893887958 0.124155160094029 DUSP16 other 5.63765567493492e-08 1 3.34610670821517e-07 6.92314547815549 -1.54162893887958 3.57604954085323e-05 93.9233448294098 22.8458253467562 4.11118195135574 5.01194512436108e-05 -97.3968659325283 89.5539985864525 -1.08757696439992 0.277602943535274 CREBL2 other 0.323954327905894 1 0.534574066964353 4.11118195135574 -1.08757696439992 0.000292674662423124 77.3209203238177 19.1096245629841 4.04617683978943 6.53240338879763e-05 1.96378355347249 53.5926014749389 0.0366428107504877 0.970792655937694 ACAD10 other 1 1 0.690017769958693 4.04617683978943 0.0366428107504877 0.236780226266045 472.977351753454 279.269522774663 1.69362323197397 0.091309994291018 306.921413390011 747.700539916942 0.410487082735162 0.681723386552021 ALDH2 other 1 1 1 1.69362323197397 0.410487082735162 3.33086087491565e-08 230.889369221338 40.1485434948117 5.75087784320683 2.08427268578674e-08 -71.8077735612848 159.560871131594 -0.450033727266775 0.652992749892525 CDKN1B ts 0.000376886907996706 1 0.000266612452177365 5.75087784320683 -0.450033727266775 0.0585088702789357 24.6730099661407 13.9235718485725 1.77203164780381 0.0773408200731803 -63.6145763262819 53.8576668451332 -1.1811610129567 0.23841587597944 GPRC5D other 1 1 1 1.77203164780381 -1.1811610129567 1.61316901761564e-05 119.006176408077 26.6370900340585 4.46768683275515 1.09828902089429e-05 -72.5699256110521 71.3166492440782 -1.01757340509205 0.309649450536281 NAA25 essential 0.151234595401466 1 0.122832644096818 4.46768683275515 -1.01757340509205 0.0203740790580935 438.392000539722 203.918112718231 2.14984335965035 0.0323215310669996 -1346.32950363626 940.444185765621 -1.43158894915194 0.153243572308195 SCNN1A other 1 1 1 2.14984335965035 -1.43158894915194 2.99760584885239e-30 1129.10831005956 89.0091196169121 12.6853103920042 3.91692627280589e-30 -522.084155609302 494.476513663806 -1.05583205912236 0.291843910141669 LTBR other 4.53238004346481e-26 1 5.95098608627398e-26 12.6853103920042 -1.05583205912236 0.777008453121778 10.7148111895318 15.1558787666234 0.706973931008749 0.480098781242942 1.49929421462057 39.0698338513254 0.0383747271699675 0.9694129148954 OGFOD2 other 1 1 1 0.706973931008749 0.0383747271699675 2.05287849921197e-05 339.684756066149 88.0388980245965 3.85834856737129 0.000138148158886533 -476.150049877997 226.952535794208 -2.09801599357212 0.0366900620422739 CDK2AP1 other 0.190383952016918 1 1 3.85834856737129 -2.09801599357212 0.00244499437540085 474.668511951833 460.130830014914 1.0315946704472 0.303041072416923 -3885.01343571691 1232.02072479223 -3.1533669503588 0.00176698304622595 OAS3 other 1 1 1 1.0315946704472 -3.1533669503588 0.0289169116535722 405.375800403069 389.952755835729 1.03955105929252 0.299333338421378 -2384.13332397936 1044.11581563419 -2.28339930138042 0.0230620140712681 OAS2 other 1 1 1 1.03955105929252 -2.28339930138042 0.503805622590031 348.169641767983 316.354116600714 1.10056934143653 0.271911329317085 -188.762220094657 1226.24949844628 -0.153934595148727 0.877758339016649 MGP other 1 1 1 1.10056934143653 -0.153934595148727 0.00349856743545 97.7215419595735 37.923299812052 2.57682064703973 0.0104190353801161 -184.813485192988 101.054958127883 -1.8288413415511 0.0683539714777053 RASAL1 other 1 1 1 2.57682064703973 -1.8288413415511 0.030138354506591 -223.14756471284 84.4862016162975 -2.64123088082817 0.0086660256114693 -75.9370667973822 331.049423131189 -0.229382870023277 0.81871788985268 ARHGDIB other 1 1 1 -2.64123088082817 -0.229382870023277 0.000172101454300981 92.7203394427015 34.4542520187828 2.69111456525467 0.00749673463527476 -250.615830547086 89.6524846960181 -2.79541421965984 0.00549736621501271 GTF2H3 essential 1 1 1 2.69111456525467 -2.79541421965984 1.70978355838317e-05 133.076245905663 30.1304819031307 4.41666503488069 1.37446281429916e-05 -85.3327097408217 78.4017184941782 -1.08840356282698 0.277238589497505 EIF2B1 essential 0.159830567037658 1 0.152757797181209 4.41666503488069 -1.08840356282698 0.00784413750806363 52.7891803788072 16.9522022524531 3.11400133107591 0.00201303077705331 4.52225122106158 44.1108706168787 0.102520108032762 0.918408267712959 DDX55 essential 1 1 1 3.11400133107591 0.102520108032762 2.41225535887152e-06 1018.44957503488 210.935111091112 4.82826007375778 2.14620789797185e-06 -527.736373631021 569.021709875473 -0.927445059603284 0.354401095730155 SLC38A1 other 0.0242335173352233 1 0.0251106324062707 4.82826007375778 -0.927445059603284 0.0693274703760305 108.962257767722 51.797851641192 2.10360573489636 0.0362004505832577 -77.6258247442979 136.280542781257 -0.569603137469847 0.569350311192527 ENDOU other 1 1 1 2.10360573489636 -0.569603137469847 0.0275279626484874 67.5034035822423 35.980971046588 1.87608620942551 0.0615563965792544 -163.795154466458 97.2120564526885 -1.6849263398329 0.0929807736359963 C12orf49 other 1 1 1 1.87608620942551 -1.6849263398329 0.00147820002185374 189.866188028416 73.5071332505715 2.58296276337154 0.0102419715109946 -389.140452831629 190.759796437602 -2.03995003191838 0.0421813018780238 VDR other 1 1 1 2.58296276337154 -2.03995003191838 0.251243783908447 49.9457176545533 59.4237256481777 0.840501283111402 0.401258894282081 -180.979528498146 145.329400723048 -1.24530568211064 0.213936235849406 FZD10 other 1 1 1 0.840501283111402 -1.24530568211064 0.414475144570858 26.9829734481929 35.448980785341 0.761177693981854 0.447113250118948 -95.4271311651676 98.0820870914848 -0.972931286384222 0.331324615252231 RFC5 essential 1 1 1 0.761177693981854 -0.972931286384222 0.124372620564354 24.1671661741856 12.5377067899813 1.92755872975888 0.0548004756419357 -8.4332253305906 30.4865190018151 -0.276621457834806 0.78225049267226 STX2 other 1 1 1 1.92755872975888 -0.276621457834806 0.345043134033867 -9.10809390329352 9.1791265689353 -0.992261500578696 0.321824391172672 18.3374089405323 22.085976551689 0.830273857151677 0.40700684943368 ADGRD1 other 1 1 1 -0.992261500578696 0.830273857151677 0.00350642486290585 279.455430672812 83.9739108845375 3.32788395501857 0.000977066395257044 0.0667359643842994 233.864557951265 0.000285361599760689 0.999772492198033 COPZ1 essential 1 1 1 3.32788395501857 0.000285361599760689 0.000297276432395913 39.8860385798499 9.79076270522074 4.07384386495052 5.86156696986665e-05 9.05644169498555 39.5666549646712 0.228890759228244 0.819102827326653 TBC1D30 other 1 1 0.621208867466468 4.07384386495052 0.228890759228244 5.21587012736529e-28 764.040073945861 62.4954086852894 12.2255392839075 2.23613450791316e-28 -433.460288000329 397.94842040488 -1.08923736287059 0.276884473692061 CAND1 other 7.84779819363381e-24 1 3.38819100639003e-24 12.2255392839075 -1.08923736287059 0.688772297120708 -0.960352430039878 1.19836685909516 -0.801384336316675 0.423515182680217 1.83529443999204 7.50622203561202 0.244503084412478 0.807000907347365 IFNG other 1 1 1 -0.801384336316675 0.244503084412478 0.00119466691830824 332.450949313729 112.594471074726 2.95264009094275 0.00338377937248347 -525.375725655317 321.692354645094 -1.63316198867995 0.103418429816117 RAB5B other 1 1 1 2.95264009094275 -1.63316198867995 0.000909789650530723 20.6192492709601 5.61863094815954 3.66979954035141 0.000285118143954413 -19.9586503092699 35.1934727775192 -0.567112272080721 0.571043095032508 MDM1 other 1 1 1 3.66979954035141 -0.567112272080721 6.40282776379299e-40 364.586638548614 23.4462095221457 15.549918130871 7.38047613121096e-41 18.4917401147466 146.869340143967 0.12590606110588 0.899886605865611 NUP107 essential 9.77839856086465e-36 1 1.12862240998478e-36 15.549918130871 0.12590606110588 2.34623210531653e-49 371.723611906572 20.7401622802653 17.9228883016154 5.7233383274087e-50 -73.6532989429863 119.770163685872 -0.614955316719454 0.539029617373459 CNOT2 other 3.59513145497651e-45 1 8.77387765591753e-46 17.9228883016154 -0.614955316719454 0.63174134823972 -7.10051259569019 93.909788138207 -0.075609930939684 0.939776682122516 -255.649506674824 268.308564195414 -0.952819032972164 0.34140091914792 TIMELESS essential 1 1 1 -0.075609930939684 -0.952819032972164 0.840369840284068 11.4062558536208 22.3068893128438 0.511333323694455 0.609475899676281 -34.0802381764615 139.732527381341 -0.243896241019486 0.807469951715423 CPSF6 essential 1 1 1 0.511333323694455 -0.243896241019486 0.154056984935425 50.9495956711579 52.2175789454856 0.975717310148534 0.329953275524729 -176.987804835004 121.991924767858 -1.45081574187635 0.147826240548911 KRR1 essential 1 1 1 0.975717310148534 -1.45081574187635 2.95044165000847e-17 576.881669022234 63.5141293759833 9.0827296963685 1.1368611532737e-17 -183.129112793937 351.114764791936 -0.521564830526156 0.60233527275638 MRPL51 other 4.17074431645197e-13 1 1.66641107846859e-13 9.0827296963685 -0.521564830526156 4.72933925417886e-29 27696.9623246156 2235.99633263498 12.3868549873588 4.87888245096846e-29 -11773.9764303304 12367.5391383905 -0.95200640148228 0.341814495960797 GAPDH essential 7.13278946315255e-25 1 7.39980101338386e-25 12.3868549873588 -0.95200640148228 1.05692524777861e-41 666.649218301577 42.1140943307445 15.8295988289817 4.68167416754408e-42 -65.442791866692 232.937640510155 -0.28094554286446 0.778934299723857 NOP2 essential 1.61561593375438e-37 1 7.16249330892569e-38 15.8295988289817 -0.28094554286446 1.03558248512209e-12 850.968676235227 111.475884839616 7.63365706815913 2.68698470906731e-13 -184.457767270548 615.631221886345 -0.299623801901005 0.764659870352877 CHD4 essential 1.36375857465728e-08 1 3.79939637862118e-09 7.63365706815913 -0.299623801901005 0.0580950072033577 2.86672281619737 1.21535959587571 2.35874454435174 0.0189414534092157 -0.529464253089442 6.71188494369648 -0.0788845842160468 0.937174040366193 ACRBP other 1 1 1 2.35874454435174 -0.0788845842160468 0.0703719811965147 46.0476173816335 20.097904830442 2.2911650627326 0.0226034352866307 0.195737636697477 50.005052828504 0.00391435716244063 0.996879241896176 UHRF1BP1L other 1 1 1 2.2911650627326 0.00391435716244063 1.40733579759043e-48 575.882200612891 33.0784239042347 17.4096021708932 3.45926166549691e-48 -226.591246183986 182.807603079711 -1.23950668553531 0.216069015692812 COPS7A other 2.15603844190854e-44 1 5.30028072387437e-44 17.4096021708932 -1.23950668553531 3.4874669462901e-11 124.114007907218 17.8163601501588 6.96629428576698 1.87756155469122e-11 -82.5896416904786 98.3917515845684 -0.839395989606834 0.401877714303492 ING4 other 4.42454931475825e-07 1 2.58408796772152e-07 6.96629428576698 -0.839395989606834 8.33994609478394e-06 9.20918964785742 1.87248154581692 4.91817378303703 1.40124649636599e-06 9.83597850374771 10.5153295953654 0.935394217988457 0.350292723986126 GNB3 other 0.080171901809158 1 0.0165809497914988 4.91817378303703 0.935394217988457 2.23419867690604e-23 196.398517889973 17.7787549877175 11.0468094096384 3.0680869702292e-24 32.0161282232593 99.840486497043 0.320672798646744 0.748668327585616 CDCA3 other 3.30929508023322e-19 1 4.61470961192175e-20 11.0468094096384 0.320672798646744 0.446937026268995 99.1967621257352 80.5600275970782 1.23133972373829 0.219102832216535 97.9153368875212 206.239892460338 0.474764293752488 0.63527984408516 CHPT1 other 1 1 1 1.23133972373829 0.474764293752488 2.8609352069367e-40 879.777327110732 56.923520852612 15.4554271052326 1.30218447978626e-40 -160.190730589733 319.666479400591 -0.501118324605406 0.616633461784497 USP5 essential 4.3703646221165e-36 1 1.99104006959319e-36 15.4554271052326 -0.501118324605406 3.06521433219285e-34 4638.27162777541 335.822029917772 13.8116955248919 2.45632123671431e-34 -1721.02362174138 1885.88204666628 -0.912582854682605 0.362151131714031 TPI1 essential 4.65759317776704e-30 1 3.74367919687627e-30 13.8116955248919 -0.912582854682605 0.258980599219557 103.325273407459 74.7450924118269 1.38236866225494 0.16782559816838 -134.753046260933 191.353209287037 -0.704211059553217 0.481815095709323 GNPTAB other 1 1 1 1.38236866225494 -0.704211059553217 2.92441936239391e-09 323.719538961957 51.4586455155377 6.29086785551343 1.04012614780529e-09 -186.842392683732 288.97727688466 -0.646564306709508 0.51837887574184 ENO2 other 3.47508752833269e-05 1 1.38378382704016e-05 6.29086785551343 -0.646564306709508 1.17779029343217e-43 1652.09829444208 101.184276649845 16.3276187678772 5.52416739409389e-44 -277.953399519163 568.22243253541 -0.489163017163779 0.625062448706689 ATN1 other 1.80178359089253e-39 1 8.45584303013952e-40 16.3276187678772 -0.489163017163779 1.04157397377516e-08 411.793008061094 66.8333056819783 6.16149394166709 2.17089193507303e-09 -62.8856444633011 375.31704318464 -0.16755339413767 0.867040807533874 C12orf57 other 0.000120749670779754 1 2.86297228397431e-05 6.16149394166709 -0.16755339413767 0.0084087009113513 79.9306972139723 29.5710200825401 2.70300777554734 0.00723957710462722 -194.805342761514 166.062529873115 -1.17308427681043 0.241637196567518 PTPN6 other 1 1 1 2.70300777554734 -1.17308427681043 1.86108687573582e-23 452.204084287936 41.3367001358202 10.9395303157273 7.2665780145554e-24 -133.724750294631 232.135279134781 -0.576063883064446 0.564978191184487 LPCAT3 other 2.75701409771504e-19 1 1.09194867824724e-19 10.9395303157273 -0.576063883064446 0.422429294868147 8.40208387587888 28.1442891869591 0.298536012761411 0.765487856330915 -87.2411481600191 71.4204348411131 -1.22151521975611 0.22279013961985 NT5DC3 other 1 1 1 0.298536012761411 -1.22151521975611 0.00681052550850487 73.1084607616178 24.9822303922094 2.92641848281154 0.00368149031718346 -69.0037904543332 100.634086060552 -0.685690039583742 0.493419397240373 SLCO1B3 other 1 1 1 2.92641848281154 -0.685690039583742 4.99689302036746e-05 176.445452734241 43.3425524644575 4.0709520483117 5.9098710507979e-05 -165.472951690638 119.922432504579 -1.37983318245583 0.168604358008393 SUDS3 other 0.446022670997999 1 0.626209936542546 4.0709520483117 -1.37983318245583 7.82907832684114e-10 234.940481376607 36.4925710971602 6.4380358608081 4.61845724814522e-10 -105.594901395707 149.010747746313 -0.70863949743732 0.47908247812954 GOLT1B other 9.50841562794856e-06 1 6.19612224411162e-06 6.4380358608081 -0.70863949743732 1.4487592564872e-08 1927.51319838135 317.080055111879 6.07894809940426 3.54997818142323e-09 -102.892525084705 1295.41726717122 -0.0794280944775339 0.93674337110561 LDHB other 0.000166781165606807 1 4.65331140020957e-05 6.07894809940426 -0.0794280944775339 0.13787516995126 33.6443308684014 32.1803797897088 1.04549203857317 0.296589670669565 -137.057324490072 89.0029735212185 -1.53991848887383 0.124574670135249 PRKAB1 other 1 1 1 1.04549203857317 -1.53991848887383 5.18474400012018e-21 297.807205140993 29.6843200958254 10.0324751983413 1.07124280375742e-20 -133.890270482774 121.274044823797 -1.1040307155361 0.270436036373888 CMAS other 7.57698488177563e-17 1 1.5950805347948e-16 10.0324751983413 -1.1040307155361 0.0139986074831331 24.8199833730646 12.6097475500903 1.96831723033875 0.0498944992849106 -59.7905056191028 31.9991614384564 -1.86850226478894 0.0626056617679951 HCFC2 other 1 1 1 1.96831723033875 -1.86850226478894 0.0153442070389334 29.1599908928974 10.312689434636 2.82758353945588 0.00499521425440996 -7.74799899794191 42.2135068668212 -0.183543125720068 0.854491875576785 ST8SIA1 other 1 1 1 2.82758353945588 -0.183543125720068 0.310746787008143 -2.66118648966728 2.40392199334579 -1.10701865411341 0.269117320439909 11.198551772875 12.7248137371599 0.88005624319453 0.379489272376421 CLEC4A other 1 1 1 -1.10701865411341 0.88005624319453 0.000183618305545742 104.674871594006 28.5875267554261 3.66155745089554 0.000294649212684593 -163.770608971741 117.018917775469 -1.3995225052925 0.162656210416609 C2CD5 other 1 1 1 3.66155745089554 -1.3995225052925 9.74390958435863e-06 163.420661592803 38.8168095340986 4.21004877923433 3.32703654490261e-05 -202.297837466964 107.357697258949 -1.88433472989848 0.0604316678385653 RAB35 other 0.0930933121689623 1 0.360251517082055 4.21004877923433 -1.88433472989848 9.24995719422542e-48 392.738117686207 22.518104588361 17.4409935856325 2.61142189790436e-48 26.239894388236 116.99723778268 0.224277896517319 0.822684652738095 PHC1 other 1.41681594343951e-43 1 4.00174291634864e-44 17.4409935856325 0.224277896517319 0.65776201959902 97.6200855754998 106.718518247185 0.914743637551163 0.361017140222619 23.9744127357599 295.27435681093 0.081193683713995 0.935338839519214 COX6A1 other 1 1 1 0.914743637551163 0.081193683713995 0.425384088023226 12.0949192105589 10.0763209266465 1.20033088451701 0.230898694708402 -9.4035264390991 27.4982316904223 -0.341968405276561 0.732599143522556 RIC8B other 1 1 1 1.20033088451701 -0.341968405276561 3.42763598344689e-06 397.130596016958 91.3319185611577 4.34821256657421 1.84861931376755e-05 -517.300782387055 250.343552183146 -2.06636351476154 0.0396009858375498 SRSF9 other 0.0340329976796442 1 0.203662389797771 4.34821256657421 -2.06636351476154 1.07746339167829e-33 170.059232441083 12.5376725721836 13.5638597564256 2.01204126709157e-33 -52.505716117829 64.4550922263281 -0.814609277626352 0.415901811422026 FGFR1OP2 other 1.63612816026349e-29 1 3.06433884978047e-29 13.5638597564256 -0.814609277626352 0.0966913170007044 -5.6409504997928 2.73706267572564 -2.06095043048194 0.0401205788578481 -14.3850181932938 14.3052185237029 -1.00557836075406 0.315382980406845 KLRB1 other 1 1 1 -2.06095043048194 -1.00557836075406 0.00873542323002221 1629.35621970921 697.872618209878 2.33474731232283 0.0201806187963314 -2562.16828544913 1677.66178630265 -1.52722575334795 0.127702017139521 COL12A1 other 1 1 1 2.33474731232283 -1.52722575334795 0.277671006159012 74.0700304233223 47.1632243576929 1.5705039558272 0.117286141472905 30.8684099523455 103.018067943742 0.299640738449907 0.764645739078055 BTN3A3 other 1 1 1 1.5705039558272 0.299640738449907 0.00014968562695571 74.0048993488864 39.5538626254826 1.87099045293262 0.0622645829816715 -238.304808179055 86.5782667769235 -2.75247838805862 0.00625422057621732 TDP2 other 1 1 1 1.87099045293262 -2.75247838805862 0.0547213749568769 -9.60450879551186 57.8683815073006 -0.165971616024896 0.868284427684498 -321.25371106306 134.983474201779 -2.37994845637797 0.0179023913833602 FRK other 1 1 1 -0.165971616024896 -2.37994845637797 3.46483482107955e-06 393.762594237625 106.339624770717 3.7028774089304 0.000251107097504821 -615.995952895799 248.047234482514 -2.48338165987182 0.0135275564899995 DSE other 0.0343884855992145 1 1 3.7028774089304 -2.48338165987182 8.70710208243758e-05 112.888025246917 34.4767694014058 3.27432144040486 0.00117548453512196 -161.124729706038 80.4203261234846 -2.0035324086927 0.0459655932019394 RWDD1 other 0.754905750547339 1 1 3.27432144040486 -2.0035324086927 0.556129388752183 -13.0681871310853 14.4756118895099 -0.90277269319133 0.36732771318593 -27.2965636140495 33.7657341219421 -0.808410192281627 0.419456951191244 RSPH4A other 1 1 1 -0.90277269319133 -0.808410192281627 0.227864762313802 -1.25245329265819 2.2279595775708 -0.562152610517187 0.57440806999376 -8.62251254199032 5.03417333390989 -1.71279611766833 0.0877247846216808 MAK other 1 1 1 -0.562152610517187 -1.71279611766833 3.1960575651857e-11 258.877226625756 54.1628919358655 4.77960495411311 2.6885608912454e-06 -346.140266768944 122.383453010522 -2.82832571114973 0.00497616256644918 TMEM14C other 4.05963231929888e-07 1 0.0313029144567702 4.77960495411311 -2.82832571114973 2.46813308636301e-20 176.8099980309 20.3668320951526 8.68127145178272 2.07555722454976e-16 -51.6100623940142 46.0197590933982 -1.12147615308612 0.262931372118924 PAK1IP1 essential 3.589899574115e-16 1 3.02118109605463e-12 8.68127145178272 -1.12147615308612 0.95517727517931 6.06929982336879 20.5399309771434 0.295487839278653 0.767814083824858 3.12870932853692 46.410883683189 0.0674132677562052 0.946295072226014 GCNT2 other 1 1 1 0.295487839278653 0.0674132677562052 0.762704297904952 -3.80621499359658 75.4220866217158 -0.0504655222903987 0.959783007423651 -117.233549166076 170.493183019872 -0.687614291020726 0.492195345749797 NEDD9 other 1 1 1 -0.0504655222903987 -0.687614291020726 0.142594912267756 -5.32929157023156 6.88514138274551 -0.774027906469287 0.439487546992445 -31.2457176962971 15.9995326344197 -1.95291440132934 0.0517038964860566 CEP85L other 1 1 1 -0.774027906469287 -1.95291440132934 0.392862630186038 40.0240879642343 31.1268364306973 1.28583860596776 0.199434907869379 7.98658565685045 69.7130888363636 0.114563646370587 0.908863296167616 ADTRP other 1 1 1 1.28583860596776 0.114563646370587 0.000138751690240097 36.8163140521437 22.6671494086162 1.6242145577489 0.105317665932851 -182.361876187501 52.6733986322016 -3.46212473322379 0.000609010624791184 ASF1A other 1 1 1 1.6242145577489 -3.46212473322379 0.0022172030144936 31.3157579769933 15.4204649130588 2.03079207751211 0.0431051295886851 -83.8585939329461 36.0081254388171 -2.32887974341885 0.0204897518055828 MCM9 other 1 1 1 2.03079207751211 -2.32887974341885 0.0638667519524984 -14.7855238926745 7.11799186118445 -2.07720438306516 0.0385825712096738 -26.0691516503277 16.6211294701599 -1.56843442541795 0.117771154009414 FAM184A other 1 1 1 -2.07720438306516 -1.56843442541795 9.77282976751357e-12 93.1322482197358 16.0599168228959 5.79904922589394 1.60058726019251e-08 -114.531062374085 38.5672563996418 -2.96964505816258 0.00320679357875805 RNGTT essential 1.25678590810224e-07 1 0.000205579427699127 5.79904922589394 -2.96964505816258 0.00404719901289677 214.392321791495 84.1691530683434 2.54716025973807 0.0113295171366998 -297.511970549377 196.542285777474 -1.51373008293097 0.131084431409785 MAN1A1 other 1 1 1 2.54716025973807 -1.51373008293097 2.44766336668597e-07 259.328598389037 105.94614452209 2.44773983573291 0.01491588419948 -1078.01554657152 246.075484656834 -4.3808327679406 1.60736298974092e-05 SERINC1 other 0.00264323166968418 0.235317941698071 1 2.44773983573291 -4.3808327679406 1.49991836401695e-05 156.31561623428 46.8495934299909 3.33654157464288 0.000949112202634863 -279.706213343355 110.248552400922 -2.53705111996569 0.0116581740192597 HDDC2 other 0.141037323768514 1 1 3.33654157464288 -2.53705111996569 0.000785697547548164 234.092460866025 96.0209672006509 2.43793066963023 0.0153207068177433 -512.735139379135 225.960821833545 -2.26913291967421 0.0239319707776646 TPD52L1 other 1 1 1 2.43793066963023 -2.26913291967421 0.010445168105064 2.96054727169464 25.8402820776897 0.114571012142733 0.908857690283205 -177.691076469509 60.8085040685343 -2.92214188116258 0.00372612446038044 HINT3 other 1 1 1 0.114571012142733 -2.92214188116258 0.160937995213362 42.0408194535785 155.47752346324 0.270398051867081 0.787029998015749 -649.784335896782 365.876641348388 -1.77596561918271 0.0766977832262059 NCOA7 other 1 1 1 0.270398051867081 -1.77596561918271 0.169518026716501 22.0698836713502 11.6871972101242 1.88838121532097 0.0598848193302953 20.740686559303 25.5817563890906 0.810760850187279 0.418109375614595 RIPOR2 other 1 1 1 1.88838121532097 0.810760850187279 0.0186129036340471 -97.0974197256402 74.2406040727161 -1.30787486091218 0.191854524537947 -448.69997758335 162.724381718134 -2.75742315223894 0.00616048967687414 SASH1 other 1 1 1 -1.30787486091218 -2.75742315223894 0.00158035916780333 86.1763667835817 38.9089020012296 2.21482391820921 0.0274762244323399 -194.069798368135 85.2825364308748 -2.275610066141 0.0235301128063426 UST other 1 1 1 2.21482391820921 -2.275610066141 0.202061024076048 -21.4291231044868 24.935824499409 -0.859370946607148 0.390779202818696 -94.6041853401852 54.6556251121541 -1.73091397538782 0.0844310409932267 ULBP1 other 1 1 1 -0.859370946607148 -1.73091397538782 0.238086846522276 -21.7639902676399 17.90867456342 -1.21527643994909 0.225156541966101 -56.6205695572999 39.5958713009118 -1.42996145045042 0.153703697106067 FBXO5 essential 1 1 1 -1.21527643994909 -1.42996145045042 8.5715915757435e-12 32.3236009732361 7.88436389598466 4.09970942483994 5.25001720807732e-05 -89.1186327768338 17.4322369312934 -5.11228898093124 5.48859790249875e-07 MTRF1L other 1.10453529045031e-07 0.00824991150724587 0.559126832660235 4.09970942483994 -5.11228898093124 3.51368219194174e-07 581.510850831531 124.728234366331 4.66222306269176 4.59942125839909e-06 -349.922482336002 288.613193700893 -1.21242718618972 0.226243258207319 PPARD other 0.00376245089113121 1 0.0527737595188712 4.66222306269176 -1.21242718618972 0.0116209872704422 86.4155742468292 30.4103654024822 2.84164866495737 0.00477605911304335 6.54049974010752 70.3676495142526 0.0929475374729231 0.926003404038751 FANCE other 1 1 1 2.84164866495737 0.0929475374729231 3.7189622547552e-10 238.771760926638 45.6941031870603 5.22543926399357 3.1395243447735e-07 -237.31571934895 106.072464153485 -2.23729807017171 0.0259550147418374 MAPK14 other 4.57134840354509e-06 1 0.00382896389088576 5.22543926399357 -2.23729807017171 0.00396241077389124 164.914399917424 62.6346455673268 2.63295814039781 0.00887527475331855 -146.383437613378 145.397561902209 -1.00678055187633 0.314800912939283 KCTD20 other 1 1 1 2.63295814039781 -1.00678055187633 0.000206075136655985 223.475084146156 63.9658971885716 3.49365980887208 0.000543551085499805 -132.793145598348 148.487876188402 -0.894302949217615 0.371831949477217 STK38 other 1 1 1 3.49365980887208 -0.894302949217615 0.357048360059114 212.364219510783 148.730751994549 1.42784337914573 0.154312120306262 121.644640842136 345.257620986206 0.352330067312245 0.724822670532037 SRSF3 essential 1 1 1 1.42784337914573 0.352330067312245 3.37968859648011e-05 150.919148690547 45.9016908929904 3.28787776124373 0.00112173607959771 -238.561096818172 101.277522960638 -2.35551867625051 0.0190999777793181 MRPL18 essential 0.306909521446359 1 1 3.28787776124373 -2.35551867625051 0.0812594982078344 327.886817372533 147.067359566112 2.22950094664027 0.0264786589057528 371.011410735208 394.254064636044 0.941046507859616 0.347395325675273 MCM3 essential 1 1 1 2.22950094664027 0.941046507859616 8.80479582618302e-15 107.607916065225 15.2577637426886 7.0526662936952 1.08864061313657e-11 -68.1785247492301 35.468044334014 -1.92225215766539 0.0554616375302714 RNF8 essential 1.20696141185317e-10 1 1.50558996796787e-07 7.0526662936952 -1.92225215766539 0.811429546154568 -1.96774801290304 5.45101118141389 -0.360987704375364 0.7183483324481 4.39413943414432 12.8798313290551 0.341164361697172 0.733205156114608 PHACTR1 other 1 1 1 -0.360987704375364 0.341164361697172 0.165662966838084 -3.76620127798115 53.7761421528576 -0.0700347984664983 0.944209707910796 -225.559771149184 125.007479874223 -1.80437019749644 0.0721134144360811 MDGA1 other 1 1 1 -0.0700347984664983 -1.80437019749644 0.00022010131422524 188.520328261613 48.1261658765282 3.917210623952 0.000109676677447903 -28.1495667384765 129.411863112792 -0.217519213937458 0.82794323550103 ICK other 1 1 1 3.917210623952 -0.217519213937458 0.000387755777955323 125.053352451047 31.7145712050327 3.94308823040946 9.89806009727601e-05 35.2781439964474 85.2808793868263 0.413670030727861 0.679394617051356 FBXO9 other 1 1 1 3.94308823040946 0.413670030727861 0.0455557882341092 68.2248363546639 29.9917536536873 2.27478650106464 0.0235821681383917 -0.271728147274261 71.055111507258 -0.00382418859826157 0.996951136744176 CD83 other 1 1 1 2.27478650106464 -0.00382418859826157 1.17321409526343e-08 261.449629682014 53.1192731807834 4.92193537347941 1.37450076260048e-06 -298.261630048152 127.074152675616 -2.34714632179786 0.0195269814749277 MDN1 essential 0.000135682210117215 1 0.0162782125314775 4.92193537347941 -2.34714632179786 2.17102140945889e-09 57.3025753362304 10.0926254435151 5.67766788304319 3.07205696284139e-08 -24.102149314026 23.4658063303753 -1.02711788270523 0.30514314751399 SAYSD1 other 2.59154825647108e-05 1 0.000390243395989742 5.67766788304319 -1.02711788270523 0.00840256493138426 24.4331463757882 13.2773798737584 1.84020843028512 0.0666635504813852 -61.2745235980708 31.7627048748945 -1.92913430513604 0.0545982431046668 BACH2 other 1 1 1 1.84020843028512 -1.92913430513604 0.393257556927726 18.4020719695138 16.5092648346838 1.11465120668811 0.26583636272794 -11.3013322315648 38.9589559942729 -0.290083035932126 0.771940596226501 RBM24 other 1 1 1 1.11465120668811 -0.290083035932126 0.0293168369023668 90.4298771498771 41.0927738028345 2.20062723396977 0.0284764811516523 -50.9336609336608 96.9717054210612 -0.525242499474476 0.599778352928232 CAP2 other 1 1 1 2.20062723396977 -0.525242499474476 0.407591685724569 0.592000903967049 1.0892850409415 0.54347657565862 0.587182489083888 4.00141192745219 2.99780501868575 1.33478058196274 0.182903018387697 TREML2 other 1 1 1 0.54347657565862 1.33478058196274 1.66435444606267e-16 181.324823064992 21.5237445779579 8.42440879226397 1.57672530337091e-15 -68.620363851722 60.3362930782438 -1.13729830506384 0.256330304267629 ZNF451 other 2.33409067515828e-12 1 2.28167918650804e-11 8.42440879226397 -1.13729830506384 3.48721453589445e-05 101.015235334839 24.1301223515722 4.18627116195528 3.74033979926374e-05 -55.0264559265626 67.6426041456248 -0.813488135496654 0.416589921757291 BAG2 other 0.316290358405627 1 0.403395647350594 4.18627116195528 -0.813488135496654 0.000117973408048953 80.2407335865701 21.3126297343461 3.7649381886112 0.000200788066307938 -65.643799283435 59.7444868044241 -1.09874237431016 0.272770340533965 RAB23 other 1 1 1 3.7649381886112 -1.09874237431016 0.212359274305357 -3.91976240317436 3.02206136430521 -1.29704924243838 0.195563452231622 -9.9620264065903 6.53881798079306 -1.52352098435107 0.128631692180373 FHL5 other 1 1 1 -1.29704924243838 -1.52352098435107 0.394255957773071 4.45758739696333 3.51524713731539 1.26807226429252 0.205708586527637 -0.886205683535961 7.64845594552373 -0.115867266523855 0.907831568321392 GPR63 other 1 1 1 1.26807226429252 -0.115867266523855 8.76472718027656e-05 24.7937788799213 17.5494774821228 1.41279299655378 0.158697649393505 -134.549134372497 38.0756250256335 -3.53373409581368 0.000470685414772011 FBXL4 other 0.759551257442766 1 1 1.41279299655378 -3.53373409581368 8.23178699663839e-11 160.871322462357 51.2617083629054 3.13823568507461 0.00185890061115298 -560.022220791731 110.842033270838 -5.05243547295221 7.3698213857981e-07 CCNC other 1.03259536085832e-06 0.0110562060429743 1 3.13823568507461 -5.05243547295221 7.13839053101128e-11 139.658686522997 22.8791565431857 6.104188598884 2.99646943972854e-09 -45.4451798883031 51.7780326842183 -0.877692286330428 0.380771276301532 E2F3 other 8.97509841464048e-07 1 3.93676154991535e-05 6.104188598884 -0.877692286330428 0.00481663511546306 455.39315281449 193.347739696312 2.35530631767285 0.0191828383319596 -958.556217421766 490.58064879385 -1.95392178590511 0.0516850042439089 PTP4A1 other 1 1 1 2.35530631767285 -1.95392178590511 0.646341428465673 -6.71809000755877 7.90197339497267 -0.850178768234388 0.395865353374799 1.86805265117304 17.3527846392049 0.107651462863925 0.914340059856853 SIM1 other 1 1 1 -0.850178768234388 0.107651462863925 3.58426292942982e-06 176.017768121381 76.7974099967148 2.29197531699195 0.0225622191667265 -612.596226065236 168.643394454294 -3.63249463785706 0.000327271060831784 ASCC3 other 0.0355092928418612 1 1 2.29197531699195 -3.63249463785706 0.0139582467855758 31.1597005601261 16.1975338394456 1.92373115987839 0.0552779150510248 -59.9771523564479 36.728567231344 -1.6329837202379 0.103459022778468 BVES other 1 1 1 1.92373115987839 -1.6329837202379 0.000899597590085927 20.2916117892455 23.3874007239669 0.867630055547433 0.386249087799627 -186.930403876814 55.6342913940184 -3.35998534703926 0.000874051608021456 MED23 other 1 1 1 0.867630055547433 -3.35998534703926 0.00187526364333101 45.2672651975089 24.9363876876501 1.81530964967824 0.070412293499385 -141.242622512737 56.3456455309192 -2.50671762088929 0.0126812983671514 WASF1 other 1 1 1 1.81530964967824 -2.50671762088929 0.0434451367829165 10.0553532023166 7.12378879129978 1.41151759223927 0.159069720942564 -20.9526894677832 15.5930482005128 -1.3437199191813 0.179996957892957 GPLD1 other 1 1 1 1.41151759223927 -1.3437199191813 0.0957474585786319 79.6175460426662 38.3477887918309 2.07619653051878 0.0386788212699257 20.2054805803194 83.9383278381842 0.240718168930783 0.809928674677206 ALDH5A1 other 1 1 1 2.07619653051878 0.240718168930783 0.000142116357672533 713.258906430333 244.861573219974 2.91290665599689 0.00383348003290438 -1238.22075537626 555.233583305191 -2.23008980833866 0.026436932578011 CRYBG1 other 1 1 1 2.91290665599689 -2.23008980833866 0.874599835111165 7.69118537394665 44.2203657590007 0.173928578878414 0.862032260463645 -45.7869357283153 105.229938505853 -0.435113204269035 0.663775410072481 VNN1 other 1 1 1 0.173928578878414 -0.435113204269035 0.0736146869495481 -15.8780117717777 7.8375124954609 -2.02589938848243 0.0436097388048203 -28.1529501742184 18.6507041219653 -1.50948457442216 0.132167922063649 VNN2 other 1 1 1 -2.02589938848243 -1.50948457442216 9.24377212463619e-08 101.483599884184 26.9666238977932 3.76330386290919 0.000199641200886652 -152.484984854657 59.026436431823 -2.58333374115819 0.0102311949279792 ACOT13 other 0.00102300826103349 1 1 3.76330386290919 -2.58333374115819 0.000564738611398095 42.563781780785 26.3109954785695 1.61771841036777 0.106721007841984 -201.152775585603 62.9171120607923 -3.19710757530071 0.00152861527874759 SMAP1 other 1 1 1 1.61771841036777 -3.19710757530071 0.00100397416057064 1999.29263609427 635.95182871827 3.1437799937202 0.00182509271678706 -1943.80074627432 1513.35636148797 -1.28443028736677 0.19992634596337 RPS12 essential 1 1 1 3.1437799937202 -1.28443028736677 2.80456584855506e-11 683.152157316428 116.135735324739 5.88235959763975 1.02421518905864e-08 -386.32195832882 254.206037232925 -1.51971984038616 0.129575011980555 C6orf62 other 3.56965141204088e-07 1 0.000132308118122595 5.88235959763975 -1.51971984038616 0.00118308602123039 34.7871883059413 19.5538831247374 1.77904245842261 0.0761939833562806 -133.9700779789 46.75892467789 -2.86512315887898 0.00444774530042873 B3GAT2 other 1 1 1 1.77904245842261 -2.86512315887898 0.0680199725929572 48.881588192398 32.6166088097505 1.49867168832663 0.134950844823517 -73.6967491207721 71.3935194048494 -1.03226104743292 0.302734262688405 GMNN other 1 1 1 1.49867168832663 -1.03226104743292 0.19018018026758 -19.3787551253171 10.9252045632687 -1.77376588356706 0.0770588060178214 -21.5798565073453 25.9983965447555 -0.830045671093454 0.407135653403735 EYA4 other 1 1 1 -1.77376588356706 -0.830045671093454 0.0675143030960456 10.5368227996044 12.0554170435842 0.874032209877973 0.382758226745067 -51.1313271599387 27.4586866132886 -1.86211845744995 0.0635057040189742 SOBP other 1 1 1 0.874032209877973 -1.86211845744995 0.114498762848072 1.53522251191224 6.01489415617339 0.255236829119689 0.798704668485802 28.3434656117953 13.7001559588819 2.0688425516368 0.0393660999719689 NR2E1 other 1 1 1 0.255236829119689 2.0688425516368 1.91850084751207e-07 213.878493212264 87.6279822765296 2.44075565425348 0.0152001857223438 -867.016858041893 199.590714712485 -4.34397391326972 1.88262808555662e-05 SNX3 other 0.00208406747065236 0.2751460947041 1 2.44075565425348 -4.34397391326972 2.26184578162791e-05 92.9343966450686 40.6785115460543 2.2846066169322 0.0229943243750092 -331.507972207325 94.7086104534613 -3.50029390802037 0.000531122607975981 HBS1L other 0.209085024053684 1 1 2.2846066169322 -3.50029390802037 0.119299212988853 59.409250611951 38.9248605017314 1.52625468264192 0.127937289473583 -57.0575844530429 84.8911292420383 -0.672126580980712 0.501989618664638 TRIM38 other 1 1 1 1.52625468264192 -0.672126580980712 1.29085218411305e-06 12.2712431466657 5.00601969516688 2.45129741669077 0.014775457281466 -47.0708664344716 11.5933032058459 -4.0601772936238 6.18828601638321e-05 PEX7 other 0.0132583427830252 0.889689880575415 1 2.45129741669077 -4.0601772936238 0.00842685494296213 14.4137739854242 14.0378251701645 1.02678112960537 0.305301477563582 -81.5359747707558 31.7173629242443 -2.57070472616218 0.0106023774199197 ZBTB24 other 1 1 1 1.02678112960537 -2.57070472616218 0.000148799367531594 2.57575230891855 11.9157581609933 0.216163526828732 0.8289980110481 -109.022321867681 26.9245527452238 -4.04917856572459 6.45323745951554e-05 FIG4 other 1 0.927330222932384 1 0.216163526828732 -4.04917856572459 0.00582240868232667 5537.95436798442 2620.85076207335 2.11303689936292 0.0353789162917735 -11654.9876345854 6070.41683495391 -1.91996496311013 0.055759513337629 PERP other 1 1 1 2.11303689936292 -1.91996496311013 0.35928523351819 -28.6929823761377 40.4091081697328 -0.710062252688597 0.478187536339363 -128.550350533921 94.0419053363485 -1.36694753338047 0.172610345818018 ARFGEF3 other 1 1 1 -0.710062252688597 -1.36694753338047 0.331592861977481 5.8750379467949 7.98329630929192 0.735916308149157 0.46232240153894 -19.7384534330315 18.2828046178528 -1.07961846366598 0.281127712418243 SLC16A10 other 1 1 1 0.735916308149157 -1.07961846366598 0.000193045535427876 136.776592062029 66.3196457673984 2.06238423742104 0.039983066456174 -478.439346244848 153.094360771335 -3.12512716885408 0.0019411450743552 HECA other 1 1 1 2.06238423742104 -3.12512716885408 0.225896667398569 90.9821794781134 55.6911290996767 1.63369249194557 0.103309948535902 -23.2615403654404 125.254345826928 -0.185714437386327 0.852786737084697 ADGRG6 other 1 1 1 1.63369249194557 -0.185714437386327 0.00261184513150239 27.1412584253376 36.9481150644133 0.734577619941397 0.463138095908134 -254.749077639985 81.1667233149421 -3.13859014181848 0.00185672203854544 PHACTR2 other 1 1 1 0.734577619941397 -3.13859014181848 0.143640830212967 -4.78830106216092 11.2788260509238 -0.424538958269396 0.671459879208105 -49.3302796308545 24.9676199638154 -1.97577020566425 0.0490449895472146 EPM2A other 1 1 1 -0.424538958269396 -1.97577020566425 5.58804437248518e-17 958.646874231946 125.996799105997 7.6085018114267 3.12542146764309e-13 -545.516708906415 289.058312526531 -1.88722027793733 0.0600355916109901 SLC39A7 essential 7.87355452083162e-13 1 4.4143452808991e-09 7.6085018114267 -1.88722027793733 0.0706591292403776 -17.4206897570556 7.6181668796839 -2.28672986982118 0.0228664095637162 -3.732058596849 17.6030794668823 -0.212011688288424 0.832233312100502 CCR6 other 1 1 1 -2.28672986982118 -0.212011688288424 0.952770657014364 0.671806537108034 9.18401346416272 0.0731495592563659 0.941732948974309 -5.86670272968329 21.2212362091602 -0.276454334321528 0.782378157089437 UNC93A other 1 1 1 0.0731495592563659 -0.276454334321528 0.0140099818686229 98.9236318945982 35.0474262999965 2.8225648025575 0.00506323077730387 24.0031151142977 80.7715826287242 0.297172772070478 0.766528024071408 PHF1 other 1 1 1 2.8225648025575 0.297172772070478 0.000367460491838162 276.09860384826 104.08655051492 2.65258674134544 0.00838726929787163 -433.516541780452 239.881677572872 -1.80720989684073 0.0716715591001368 CUTA other 1 1 1 2.65258674134544 -1.80720989684073 0.000140091623926028 147.341357908461 89.951902666746 1.63800157128785 0.102410418647881 -672.5643171002 194.629789971323 -3.45560829716405 0.000623617076356758 QKI other 1 1 1 1.63800157128785 -3.45560829716405 0.940149776286101 0.906583915124184 9.71848090042882 0.0932845291782362 0.925736266400029 -6.89118313248217 22.4547308785241 -0.306892261134733 0.759126239527727 PDE10A other 1 1 1 0.0932845291782362 -0.306892261134733 7.19755905257366e-05 286.57071678238 85.1629933564913 3.36496764014386 0.000858955799180007 -397.478583911887 232.748538064305 -1.70775974456205 0.0886538328176657 MDFI other 0.630506173005452 1 1 3.36496764014386 -1.70775974456205 0.000137017315695427 75.3635738584223 20.8521929091557 3.61417977412496 0.000350138493652099 -61.974119292115 57.1357596328429 -1.08468181206242 0.278884246008691 TFEB other 1 1 1 3.61417977412496 -1.08468181206242 0.07014221386449 130.097880286711 60.4596741948362 2.15181246044197 0.0321623347465159 -44.6964039870903 139.702433170862 -0.319940053817279 0.749223218649692 SMOC2 other 1 1 1 2.15181246044197 -0.319940053817279 0.00251697413638856 149.098212769502 54.7474042152303 2.72338414773689 0.00681855712588672 -192.618070654793 150.401432128688 -1.28069306208456 0.201234771187254 CCND3 other 1 1 1 2.72338414773689 -1.28069306208456 4.46778310148098e-16 168.52680614391 22.444064146511 7.50874730368776 6.06868002220734e-13 -143.784670150898 61.6580719910062 -2.33196831344112 0.0203264002133462 BYSL essential 6.23479131811671e-12 1 8.53681218723907e-09 7.50874730368776 -2.33196831344112 1.01355133889494e-10 101.226657177772 27.4599342599866 3.68634011354045 0.000267671083347232 -313.392513875275 63.4382078547603 -4.94012243524875 1.26787835361911e-06 FAM120B other 1.26734459415424e-06 0.0189712638052027 1 3.68634011354045 -4.94012243524875 5.27989305449444e-08 41.9040560555016 10.2922993843238 4.07139886732462 5.91174012575592e-05 -76.8819471669369 23.7773703849526 -3.23340831732979 0.00135248750500714 TBP essential 0.000590925630659018 1 0.626348866323839 4.07139886732462 -3.23340831732979 0.031744474261548 2.93059077545282 1.17659397683923 2.49074092944576 0.0132559334039126 -0.893336863441551 4.08879937905449 -0.218483907040734 0.82719180270775 PRPH2 other 1 1 1 2.49074092944576 -0.218483907040734 2.97684335131669e-07 71.7662735982858 13.1655913062054 5.45104826127027 1.00401665241744e-07 3.78885024490131 45.7519438458365 0.0828128802060964 0.934052266510756 BICRAL other 0.00319742744364926 1 0.0012502015355902 5.45104826127027 0.0828128802060964 6.6703527105352e-36 351.617630254401 25.3599405531635 13.865081012997 1.54442885641831e-34 -60.2432748859736 88.128709841936 -0.683582852784564 0.494734832168179 PPP2R5D other 1.01556120017898e-31 1 2.35417290583843e-30 13.865081012997 -0.683582852784564 7.46900391799545e-22 206.291682393587 20.2041577750223 10.2103579219035 2.34525208848481e-21 -29.2133014421669 70.1375875755686 -0.416514203752611 0.677314765936404 MRPL2 essential 1.09704729547517e-17 1 3.50146136810782e-17 10.2103579219035 -0.416514203752611 3.31318324528218e-15 1017.02763708853 134.327542006665 7.57125174700262 4.04131555930516e-13 -962.198299041676 466.310441950254 -2.06342859280068 0.0398831583161197 PTK7 other 4.5662291486479e-11 1 5.69785080706435e-09 7.57125174700262 -2.06342859280068 1.11112243734061e-12 256.540028555955 36.6191562836571 7.00562368419307 1.47271120571689e-11 -183.732173313783 127.121323709105 -1.44532929608429 0.149350130124592 SRF essential 1.46245935202771e-08 1 2.03086875268359e-07 7.00562368419307 -1.44532929608429 0.918310608247793 15.1512495617769 42.6373464841849 0.355351606305915 0.722562525508582 36.0136475184053 117.760547686663 0.305820992054404 0.759941679646324 CUL9 other 1 1 1 0.355351606305915 0.305820992054404 1.83800674848957e-06 120.917557720239 26.5735257980437 4.55030162874136 7.6409115698211e-06 -84.7707874242499 73.3937078636924 -1.15501437237218 0.248954433400546 DNPH1 other 0.0186153323487024 1 0.0864721962356654 4.55030162874136 -1.15501437237218 0.000242513792365739 61.2760892738336 31.1347587852998 1.96809262908968 0.0499397827075799 -176.114729371701 69.6865663509746 -2.52724073797386 0.0119884313602761 DUSP22 other 1 1 1 1.96809262908968 -2.52724073797386 1.0898633466506e-11 148.477871346097 24.0774750140106 6.1666711837391 2.14309039145667e-09 -64.8666085028703 53.8486985580244 -1.20460865795992 0.229261571655944 EXOC2 other 1.40014744144203e-07 1 2.82737915344879e-05 6.1666711837391 -1.20460865795992 0.118651184049539 168.806706894845 98.6891985077553 1.71048817345071 0.0881509371139183 -187.473725970258 235.126514258027 -0.797331285932836 0.425853590173594 COX7A2 other 1 1 1 1.71048817345071 -0.797331285932836 0.0403051107231006 38.8142249480708 162.471155264213 0.238899174964015 0.811337651839332 -942.417664127674 387.086702317753 -2.43464231265185 0.0154562365143658 TMEM30A other 1 1 1 0.238899174964015 -2.43464231265185 0.00203797379045067 90.5738574307945 37.3434437098671 2.42542862769944 0.0158502015612241 -114.142971547049 83.1801482086897 -1.37223813620381 0.170962588888612 GMDS other 1 1 1 2.42542862769944 -1.37223813620381 1.98368464255858e-05 116.903551290932 43.7989393404675 2.66909548613018 0.00799588831299459 -342.972229778744 104.350750548589 -3.28672508799107 0.00112691565904356 SENP6 essential 0.184165282215139 1 1 2.66909548613018 -3.28672508799107 0.00170753363436653 560.208647312376 188.612882313646 2.97015050319204 0.00320310808157578 -562.428873394203 524.45541854982 -1.07240549625626 0.284351096907014 VEGFA other 1 1 1 2.97015050319204 -1.07240549625626 6.91397488081969e-09 287.940292522248 48.7207016479097 5.91001941234567 8.80662462199617e-09 38.7129066291937 108.089665814409 0.358155484499916 0.720464585361306 PRPF4B other 8.08520222563055e-05 1 0.000113940109359386 5.91001941234567 0.358155484499916 0.118587739918391 27.1505748632673 32.5835753152327 0.833259536456534 0.40532181794615 -112.040076050698 69.8276935299143 -1.60452207980634 0.109588550283332 TTK essential 1 1 1 0.833259536456534 -1.60452207980634 5.39504624476593e-12 349.301336217706 50.9467303878499 6.85620713161623 3.68657103292506e-11 -125.845009634492 141.662056597348 -0.888346623345917 0.375025768340987 SLC29A1 other 6.98874290546979e-08 1 5.04986500090075e-07 6.85620713161623 -0.888346623345917 0.00932406738460996 35.5894949184751 12.3679084307686 2.87756778906418 0.0042777729800684 -10.6893258043136 28.3241463940216 -0.377392690166642 0.706132751059457 WISP3 other 1 1 1 2.87756778906418 -0.377392690166642 0.0011184451599647 59.7300367761015 18.1670651263215 3.28781981903951 0.00112195933804847 -14.3517424460419 39.6821034823185 -0.361667885182465 0.717838918798569 BTN2A1 other 1 1 1 3.28781981903951 -0.361667885182465 0.0435592369177812 132.992201449409 120.574738296114 1.10298561148687 0.270864806148275 -533.1548694102 276.132100915607 -1.93079641100165 0.0543941932666913 LAMA4 other 1 1 1 1.10298561148687 -1.93079641100165 0.0331127102612279 40.5421348314611 47.4806385180915 0.853866672749427 0.393821610347912 -221.226487723679 101.396388519662 -2.18179849355068 0.0298561957056441 FAM46A other 1 1 1 0.853866672749427 -2.18179849355068 0.829078155363619 11.6668482650452 24.1184797616095 0.483730665463247 0.628908911552788 -14.5409978278749 66.9237000405163 -0.217277254830077 0.828131183867608 CLIC5 other 1 1 1 0.483730665463247 -0.217277254830077 0.00295130140736743 188.840692108596 56.2147730552903 3.35927162639012 0.00087685302062438 2.09976331073198 136.551750161134 0.0153770516178241 0.987741044687306 FBRSL1 other 1 1 1 3.35927162639012 0.0153770516178241 0.569774801400202 -2.95124114209426 11.7361358575576 -0.251466170630069 0.801615629250871 29.7097763425781 32.5653044275259 0.912313791160688 0.362292494636214 ENPP5 other 1 1 1 -0.251466170630069 0.912313791160688 0.604080604392805 -3.94582073305257 5.06888985700471 -0.778438838555513 0.436889176429037 2.87340465165015 11.3438200205116 0.253301325872108 0.800199047886084 LY86 other 1 1 1 -0.778438838555513 0.253301325872108 0.000177524627705469 53.4301669435204 13.3040959309778 4.01606897760798 7.37922687761323e-05 9.84185211061564 30.1898809467512 0.325998374355124 0.744638666841224 PRSS16 other 1 1 0.775778121643478 4.01606897760798 0.325998374355124 0.212054426631726 28.3908370856108 18.6336025648657 1.52363650489909 0.128593362843509 -18.8984821282841 41.2177181148433 -0.45850384234343 0.646903692767345 TBX18 other 1 1 1 1.52363650489909 -0.45850384234343 1.16484174522386e-05 202.492804815789 87.5448957701452 2.31301668743141 0.0213615575443659 -366.467206420046 122.985576135076 -2.97975761009203 0.00310773450097978 ERBIN other 0.110508536369388 1 1 2.31301668743141 -2.97975761009203 0.149898720875178 37.7196739843826 22.925193894766 1.64533718482504 0.100888325192954 55.4763178717411 36.2505418772957 1.53035830635367 0.126922197283188 PCDHB2 other 1 1 1 1.64533718482504 1.53035830635367 1.30677713902574e-14 109.151390556213 22.2624460990042 4.90293789239518 1.51691326500057e-06 -165.975900025992 34.7220910818222 -4.78012397452882 2.69602965160794e-06 HARS2 essential 1.78492689419526e-10 0.0401411854827906 0.0179132287463917 4.90293789239518 -4.78012397452882 0.08794445077067 6.1948900772432 12.738003463577 0.486331323033226 0.6270651604385 -32.4216208971624 18.0310019485346 -1.79810423124032 0.0731029305946402 NUDT12 other 1 1 1 0.486331323033226 -1.79810423124032 1.23545998246999e-10 45.5219668635953 6.55732990955656 6.94214985237394 2.16767772864842e-11 -5.0856242158591 39.2186681037587 -0.129673557562035 0.896906429599358 CEP72 other 1.5396302301541e-06 1 2.98034010911872e-07 6.94214985237394 -0.129673557562035 3.02150950847536e-06 274.141248570508 80.8651817154852 3.39010242424288 0.000786150926141395 -262.243742885855 114.503430314407 -2.29026975144568 0.0226558953820856 MAN2A1 other 0.0301395573470417 1 1 3.39010242424288 -2.29026975144568 0.0758227666726172 37.1920382729386 37.0452528350835 1.00396232787257 0.316160092871236 -423.437464723435 218.439737759152 -1.93846352805235 0.0534513956106223 SEMA5A other 1 1 1 1.00396232787257 -1.93846352805235 0.219548333642211 -50.5325958452963 29.6600968856991 -1.70372322248418 0.0894221706275217 -107.919481506502 203.314224794171 -0.530801431211993 0.595931606322053 C7 other 1 1 1 -1.70372322248418 -0.530801431211993 5.60931875856534e-19 182.884992624882 19.1221070259871 9.56406071654869 3.21455683233565e-19 -120.378133875931 108.705951681915 -1.10737390192002 0.268966600361207 PAPD7 other 8.07293155732723e-15 1 4.75432955502442e-15 9.56406071654869 -1.10737390192002 0.848931806146388 -0.993347983889796 12.2381143539984 -0.0811683855172717 0.935360251004475 -49.3050156499384 86.2417910127762 -0.57170676850431 0.567933608288405 GHR other 1 1 1 -0.0811683855172717 -0.57170676850431 0.000385528988414632 613.273651376197 154.699340420785 3.9642938987851 9.1443241994468e-05 1085.06566621927 1089.58871791267 0.995848844964116 0.320100271889372 HMGCS1 essential 1 1 0.951741262678423 3.9642938987851 0.995848844964116 7.75676924402548e-13 542.08962172409 70.837839721763 7.65254310201032 2.37373270288766e-13 -327.92766706703 417.699919639699 -0.785079555078427 0.432991419735282 DAP other 1.024358946366e-08 1 3.35811965477518e-09 7.65254310201032 -0.785079555078427 2.77902575361531e-07 114.175217554294 46.9186083571486 2.43347408527513 0.0155018007788232 -275.153104097518 69.864533642422 -3.93838031619586 0.000100723709195199 BRD8 essential 0.00299134332119152 1 1 2.43347408527513 -3.93838031619586 1.47102034063742e-06 182.406902804552 69.8980035919057 2.60961534566167 0.00949036605838001 -359.073158621537 103.837737313774 -3.45802179352677 0.000617777687559942 KIF20A essential 0.0150352989016551 1 1 2.60961534566167 -3.45802179352677 1.05381527116993e-06 259.203130579692 49.7320944647742 5.21198902578472 3.4236642224099e-07 -279.007161845812 350.020434329246 -0.797116780854468 0.425995275081177 NNT other 0.0108911808275412 1 0.00416831119078405 5.21198902578472 -0.797116780854468 1.54504156370244e-34 250.485724105525 17.6157173613293 14.2194449971933 1.4118485695343e-35 48.9752832071833 123.935570348171 0.395167287886741 0.692994757367313 MRPS30 other 2.34892668929683e-30 1 2.15405736253849e-31 14.2194449971933 0.395167287886741 5.68551787434917e-11 1048.45723423157 229.720939202252 4.56404730832345 7.16280555714233e-06 -1227.83527391175 337.306520061131 -3.64011722539258 0.000317663312167603 HSPA9 essential 7.17284935027891e-07 1 0.0812405406291084 4.56404730832345 -3.64011722539258 2.41417770461472e-15 306.24137465295 55.9264627157512 5.47578659157179 8.83855017488337e-08 -308.80585687336 76.5725058904899 -4.03285556979157 6.89970154872034e-05 MRPS27 essential 3.33735925885939e-11 0.990521154334293 0.0011029626763237 5.47578659157179 -4.03285556979157 2.27529235621945e-13 189.232665894959 38.0743820973497 4.97007844831528 1.09254414688353e-06 -237.009235200689 55.9058193534016 -4.23943764606086 2.93560498449739e-05 PFDN1 essential 3.03888047096669e-09 0.426836964745921 0.013001275347914 4.97007844831528 -4.23943764606086 0.27999180803897 149.424026166314 208.705396046131 0.715956697800408 0.474540205369495 -339.71337389291 306.44873341877 -1.1085487941263 0.268457340596557 HBEGF other 1 1 1 0.715956697800408 -1.1085487941263 0.00237959930802408 244.474672779037 166.005767499565 1.47268782561834 0.141818102245782 -579.967266740588 244.080854825333 -2.3761276448971 0.0180836491343534 LOX other 1 1 1 1.47268782561834 -2.3761276448971 0.00119754587389271 -18.6353983428245 13.6176910801394 -1.36846975255616 0.172137209933461 -85.3961066945664 23.0354275146331 -3.70716396039618 0.000247445399891333 GZMK other 1 1 1 -1.36846975255616 -3.70716396039618 1.55256992006152e-09 47.5817078095137 9.34735969739332 5.09039015827996 6.10846599432096e-07 -30.5506581958165 13.7250238582365 -2.22590929614179 0.026716491783442 TMCO6 other 1.86137607716176e-05 1 0.00735520390376187 5.09039015827996 -2.22590929614179 0.190006701339801 -358.970019101889 3422.23378142268 -0.104893482453048 0.916526252454044 8213.24758717352 4911.91393246009 1.67210739033857 0.0954836491415069 SPARC other 1 1 1 -0.104893482453048 1.67210739033857 0.000415397603551321 397.513971081885 167.188830177088 2.37763474187142 0.0180112291859008 -460.77890257851 229.975933364886 -2.00359618433389 0.0459560722018625 HMGCR essential 1 1 1 2.37763474187142 -2.00359618433389 3.96232811833076e-05 94.0498545391271 51.2422039827434 1.83539830899545 0.0673746034481987 -219.816706865255 70.486010794639 -3.11858628949354 0.00198236283929938 COL4A3BP other 0.357718982522901 1 1 1.83539830899545 -3.11858628949354 5.91329361460978e-16 360.994723892057 61.8063660982597 5.84073691241042 1.27745205018031e-08 -399.418300849948 94.1115512961707 -4.24409432581737 2.87850252874612e-05 FAF2 essential 8.24017465195873e-12 0.418649407780836 0.00016451027502222 5.84073691241042 -4.24409432581737 0.15449356354471 12.5242135136135 6.90643738251004 1.81341157820817 0.0707109487100908 13.4902343981747 10.9208279200099 1.23527579566169 0.217639723564659 PCDHB3 other 1 1 1 1.81341157820817 1.23527579566169 0.0297750999599997 28.461577744539 13.4133358179978 2.1218866157328 0.0346201755039579 46.9615276072606 21.2098835026897 2.21413416067586 0.0275285558277802 PCDHB5 other 1 1 1 2.1218866157328 2.21413416067586 0.287530314027241 13.6070475098991 8.60161592770905 1.58191758667876 0.114662429770126 6.79513698644481 13.6013348384818 0.499593390438383 0.617706896921648 PCDHB6 other 1 1 1 1.58191758667876 0.499593390438383 0.881589068012024 -4.17063984240843 8.30570159113598 -0.502141787378856 0.615915299238861 -2.09362502759877 13.133419273655 -0.159412030026216 0.87344546136544 PCDHB7 other 1 1 1 -0.502141787378856 -0.159412030026216 0.00212259209201109 20.0732836860036 11.005571745021 1.82392011528931 0.0690967197896524 -31.2518275853495 15.1386706372343 -2.06437066597407 0.0397881412910887 PDE8B other 1 1 1 1.82392011528931 -2.06437066597407 7.00051626467021e-06 49.8253749840355 21.084938185563 2.36307901619324 0.0187214572837726 -107.726126607666 32.7595208514564 -3.28839139913355 0.00111975877307852 CLK4 other 0.0677579969257429 1 1 2.36307901619324 -3.28839139913355 0.330865039645567 11.3163615737661 7.7441264123266 1.46128316755696 0.144925140264653 9.16429462665642 12.2454265862157 0.748385085822358 0.454781052178512 PCDHB15 other 1 1 1 1.46128316755696 0.748385085822358 0.000582120361844536 -14.8197326279724 13.6196603003036 -1.08811323492716 0.277363960241623 -77.2608459247627 19.8162776829432 -3.89885765434469 0.000117774867596079 ITK other 1 1 1 -1.08811323492716 -3.89885765434469 0.00941244553973337 71.7946203160901 74.4738830478235 0.964024130042837 0.335761762422911 -290.215446118831 118.778489727311 -2.4433333576231 0.0150923629825272 RNF130 other 1 1 1 0.964024130042837 -2.4433333576231 1.51961700566778e-12 66.6043792876195 15.4005195199176 4.32481379615016 2.04217566038726e-05 -100.804766935692 22.0823789848353 -4.56494144063546 7.13420908070523e-06 THG1L essential 1.99434535823839e-08 0.105429341794662 0.224373839806749 4.32481379615016 -4.56494144063546 0.0347769529747844 9.99170911254059 22.2342186011258 0.449384315760693 0.653458657771295 -66.439399065571 30.5556951910671 -2.17437039642267 0.0304096798931068 ARSB other 1 1 1 0.449384315760693 -2.17437039642267 0.000603654890033806 156.980039321584 148.781718695217 1.055103010627 0.292174165413839 -678.968013245744 213.333991362683 -3.182652745157 0.00160261744275914 CLINT1 other 1 1 1 1.055103010627 -3.182652745157 0.360018304882034 470.305291074302 333.472390085157 1.41032752652837 0.159417319421614 157.134804387387 460.271972371136 0.341395552672678 0.733030588260929 THBS4 other 1 1 1 1.41032752652837 0.341395552672678 2.27928235698443e-18 236.062396846681 47.3446301465939 4.9860437417244 1.01506778170437e-06 -464.08285112625 75.7512662232485 -6.12640387764 2.65358305465755e-09 CNOT6 other 3.26096926813762e-14 4.04352985868717e-05 0.0120996079579161 4.9860437417244 -6.12640387764 4.49696681392125e-15 206.356182261848 38.5190551572442 5.35724932554684 1.61825878316175e-07 -249.297102865382 55.2314078119224 -4.51368365829647 8.96399602506146e-06 TTC1 essential 6.18917542599981e-11 0.132084481429281 0.00199806411956981 5.35724932554684 -4.51368365829647 4.89574654705636e-10 55.4357805457887 20.1014361693374 2.75780198383786 0.00615352370511844 -126.418203800038 27.8221756761717 -4.54379288203218 7.84088836682658e-06 MSH3 other 5.9938624975611e-06 0.115692307852526 1 2.75780198383786 -4.54379288203218 0.906022210085747 5.01022722090971 12.7720535778807 0.392280473172041 0.695112134194072 -0.571342214137545 17.6776582228149 -0.0323200169918529 0.974236995491428 RASGRF2 other 1 1 1 0.392280473172041 -0.0323200169918529 2.98585583036064e-09 205.256737722062 61.2854067663791 3.34919434416914 0.000907598345466353 -356.032479907201 87.7544846932092 -4.05714284747834 6.25193631810523e-05 CCNG1 other 3.54630096971933e-05 0.898715845727627 1 3.34919434416914 -4.05714284747834 0.0028924912798053 29.8702167287505 16.8171501612739 1.77617589438756 0.0766570435943641 -46.9288291322505 23.3961079768336 -2.00583914122463 0.0457174707109068 POLR3G other 1 1 1 1.77617589438756 -2.00583914122463 1.02901032579065e-20 295.55027610773 28.8862794223283 10.2315106693622 2.10666269337932e-21 -90.9351213412249 185.941534732323 -0.489052225325196 0.625145060194713 DROSHA other 1.50122316429598e-16 1 3.145668733754e-17 10.2315106693622 -0.489052225325196 0.777100232763107 -4.89525364568136 6.89188595623417 -0.710292317192695 0.478048397268031 -3.77615832977756 44.3632020990482 -0.0851191562175034 0.932220734664375 CDH6 other 1 1 1 -0.710292317192695 -0.0851191562175034 1.73269851746437e-06 98.9092731875044 136.835333172567 0.722834306712046 0.470309648657871 -912.825098500451 201.685141653939 -4.5259908142699 8.48742132022441e-06 LMNB1 other 0.0176007515404031 0.125113077681428 1 0.722834306712046 -4.5259908142699 2.98981335625794e-05 22.3934702830387 150.896181072779 0.148403161192251 0.882118369740838 -881.997133482864 210.565197899587 -4.18871277058549 3.63475996551829e-05 ARRDC3 other 0.273298838895538 0.526931152201186 1 0.148403161192251 -4.18871277058549 1.13641006622313e-15 424.889377747645 48.647097231361 8.73411574234143 1.45672862743965e-16 25.7462310504131 315.127367486853 0.0817010317312004 0.934936181303977 GOLPH3 other 1.57767809493757e-11 1 2.12259928304231e-12 8.73411574234143 0.0817010317312004 2.09867148710936e-14 697.318641360945 84.3229493539001 8.26961873017897 3.78209229391187e-15 -181.484922454344 546.22928316248 -0.332250445094427 0.739920435542254 SUB1 other 2.85587215965842e-10 1 5.45718097088544e-11 8.26961873017897 -0.332250445094427 0.00206020836828466 104.50036052848 32.1974521817134 3.24560961962793 0.00129764448990436 365.83680873469 208.569450661205 1.75402873035776 0.0803949463802704 NPR3 other 1 1 1 3.24560961962793 1.75402873035776 0.184492389830677 9.41821184425255 6.838435566076 1.37724655782007 0.16939861609187 -6.33889435040895 10.0927720904981 -0.628062765469233 0.530410789427527 SLC27A6 other 1 1 1 1.37724655782007 -0.628062765469233 5.6274439242494e-22 668.383838189692 62.7561360329448 10.6504938073117 7.76580132472234e-23 880.746412188308 406.523247371886 2.166533938421 0.031017536144306 TARS essential 8.27009159107691e-18 1 1.16440425062887e-18 10.6504938073117 2.166533938421 2.4339903210523e-13 173.388661819071 21.8980305530655 7.91800255273634 4.07014876519409e-14 -14.5264950293831 128.452920417331 -0.113088086920779 0.91003207701884 IRX4 other 3.24816008344429e-09 1 5.81705661521539e-10 7.91800255273634 -0.113088086920779 2.01942833839924e-06 146.06822221725 75.1752448622243 1.94303620141115 0.0528885212035539 -393.014392455326 107.006946159479 -3.67279327707934 0.000281104792622989 LNPEP other 0.0203881485044787 1 1 1.94303620141115 -3.67279327707934 0.234961653288289 -16.7295847721869 30.8108629275988 -0.542976832927369 0.587528527796958 -86.5102480502726 50.857547526175 -1.7010306681766 0.0899209607109517 PDE4D other 1 1 1 -0.542976832927369 -1.7010306681766 2.22352800664115e-15 151.643262355248 17.7873784852806 8.52532949027515 6.25117019630907e-16 -77.8796589255203 114.419729307821 -0.680648865336872 0.496588977977108 RAD1 other 3.07558393878604e-11 1 9.06794748676593e-12 8.52532949027515 -0.680648865336872 1.31354691681636e-20 277.421584509269 27.0206205218273 10.2670323312956 1.50971887814995e-21 42.7719103967601 173.813813451783 0.24607889066668 0.80577992016979 BRIX1 essential 1.91462598595153e-16 1 2.25597291961947e-17 10.2670323312956 0.24607889066668 0.0204388034734849 34.3985775654232 12.2916371127039 2.79853507307589 0.00544779982895815 38.941305396046 77.6962246573186 0.501199454256596 0.616578613236849 PRLR other 1 1 1 2.79853507307589 0.501199454256596 0.415301588799876 62.6493838084585 83.8959447103197 0.746751038143471 0.455765593825436 -518.660863102314 510.719488976372 -1.01554938532277 0.31061605615863 SLC12A7 other 1 1 1 0.746751038143471 -1.01554938532277 1.26904806205553e-11 266.537170668918 56.0522824790973 4.75515284802743 3.00706373452785e-06 -289.386557258357 83.8873233708557 -3.44970545762933 0.000636657668411955 RAD50 other 1.62768104439242e-07 1 0.0348999817029302 4.75515284802743 -3.44970545762933 0.0378563432278596 -40.116326772376 36.4419332620707 -1.10082872069056 0.271798575829408 -132.913164955842 51.7113842432643 -2.57028828179463 0.0106134381568853 ST8SIA4 other 1 1 1 -1.10082872069056 -2.57028828179463 0.00986200275587345 66.0683721522284 40.109352035291 1.64720617012453 0.100500336018609 -107.384381072952 57.190031684057 -1.87767654451025 0.0613376429000729 GNPDA1 other 1 1 1 1.64720617012453 -1.87767654451025 0.884242582017612 -5.90076011616288 17.6278927714605 -0.334739959714084 0.738041245463792 5.84415948328003 25.1347801688731 0.232512854459631 0.816288807014091 PCDH12 other 1 1 1 -0.334739959714084 0.232512854459631 1.64491330626066e-08 334.545251079011 114.796506288381 2.91424592869227 0.00381750215724368 -680.073582126026 171.421087068208 -3.96726910181959 8.98284472187754e-05 SKP1 essential 0.000189049886288538 1 1 2.91424592869227 -3.96726910181959 4.57237327086762e-12 270.89041594656 36.418669467778 7.43822934515042 9.6975573832949e-13 -130.920789075092 244.563526164645 -0.535324261668329 0.59280217876191 NUP155 essential 5.934026030932e-08 1 1.36144008104077e-08 7.43822934515042 -0.535324261668329 1.81760673653275e-20 696.61357988196 110.380975277784 6.31099315918228 9.26697327434293e-10 -854.413472695507 164.827549073954 -5.18368123226871 3.86918149945794e-07 PPP2CA essential 2.64625364771803e-16 0.00582466582928398 1.23454617960797e-05 6.31099315918228 -5.18368123226871 0.00489859879540228 34.2718737341259 23.338060343124 1.46849709145701 0.142954614487578 -75.6366697867722 33.362732674221 -2.26710055574122 0.024053043948417 FGF1 other 1 1 1 1.46849709145701 -2.26710055574122 7.82650801285389e-05 304.839889369745 88.1833124810702 3.45688861977353 0.000620527193754998 -176.947557048732 126.06173081132 -1.40365800080576 0.161393422059185 NR3C1 other 0.682158438400345 1 1 3.45688861977353 -1.40365800080576 2.72546961103424e-06 139.553565825992 63.4075563244196 2.2008980303858 0.0284593558398838 -333.388451791965 94.8951576329813 -3.51322933759576 0.000506637252795852 C5orf15 other 0.0272683234583975 1 1 2.2008980303858 -3.51322933759576 7.05108627195866e-12 88.3119575412897 20.8288889969514 4.23987844739176 2.93739056765238e-05 -114.930671519281 29.2610196289388 -3.92777397974251 0.000105250261664395 PPWD1 essential 9.10577281160742e-08 1 0.319088737364078 4.23987844739176 -3.92777397974251 0.444711600710573 38.8237687956959 34.8973633078827 1.1125129555827 0.266763278272759 -125.191974755138 240.790095917781 -0.519921611717307 0.603482233486111 LIFR other 1 1 1 1.1125129555827 -0.519921611717307 1.06259408957946e-06 31.0090058535082 10.5287690596399 2.9451691529996 0.00346660484590872 -43.2023931455151 14.7911162312968 -2.92083386202471 0.0037413854494461 TRIM23 other 0.0109797847276246 1 1 2.9451691529996 -2.92083386202471 5.62426762134839e-06 19.6848782399109 9.70571709326958 2.02817350338403 0.04337843022101 -46.1447323115261 13.6348692635817 -3.38431791456756 0.000803182707937444 TRAPPC13 other 0.054887227716739 1 1 2.02817350338403 -3.38431791456756 0.153156881453743 0.76858840681344 0.746140909519593 1.03008479632661 0.303760471080518 8.92376169560968 5.14873570129894 1.73319475174427 0.0840396562485404 C9 other 1 1 1 1.03008479632661 1.73319475174427 4.2545082909171e-06 132.132697586929 43.8197777643246 3.01536667523912 0.0027727853651879 -175.135030658995 65.434342754106 -2.67650018763282 0.00782398358778567 SEC24A other 0.0419324337152789 1 1 3.01536667523912 -2.67650018763282 0.0358578105226303 43.7655146595143 30.8797458912827 1.41728869186936 0.157374477081815 -68.9558210552608 46.1115044370429 -1.49541468874449 0.135794851183659 TXNDC15 other 1 1 1 1.41728869186936 -1.49541468874449 2.98557250310549e-09 37.1991955909513 5.75331021062772 6.46570308728279 3.85432242798891e-10 16.9741009193201 40.6540175634696 0.41752579293842 0.676579205767665 TTC33 other 3.54626301918871e-05 1 5.1782821820031e-06 6.46570308728279 0.41752579293842 8.40881106006262e-16 389.274252675966 53.8990574513671 7.22228311742198 3.75656523932574e-12 -164.377794429874 78.440572592512 -2.09557106733265 0.0369057242705393 RARS essential 1.16958153034411e-11 1 5.23101709576109e-08 7.22228311742198 -2.09557106733265 3.23131989136304e-06 284.35494609085 66.8527560060742 4.25345136205025 2.76695314673405e-05 -112.243783700038 97.0604454392969 -1.15643178013475 0.248367186982255 WWC1 other 0.0321451702792796 1 0.301044502364664 4.25345136205025 -1.15643178013475 1.09262209864869e-15 758.324819650527 189.333207928168 4.00523937638151 7.71369269014699e-05 -1633.93846107197 281.726425420678 -5.79973447159651 1.59878545734587e-08 H2AFY other 1.51732430839343e-11 0.000242711620279676 0.809089226269518 4.00523937638151 -5.79973447159651 5.96117521328846e-08 225.216304493989 51.3357159264686 4.38712698224722 1.56124291834519e-05 -165.247779408568 74.6847657370393 -2.21260357152884 0.0276306258756354 TCERG1 essential 0.00066544598905939 1 0.172876428348363 4.38712698224722 -2.21260357152884 0.0639994801628618 -346.235851972027 325.789464153296 -1.06275951210353 0.288692376625128 760.090308552081 473.968451998137 1.60367278739276 0.109772702296374 DPYSL3 other 1 1 1 -1.06275951210353 1.60367278739276 0.0921453214944436 54.1311338823816 76.163802834752 0.710719946584425 0.477777089446146 -189.008582350042 112.7838689893 -1.6758476548448 0.0947478315071718 SMAD5 other 1 1 1 0.710719946584425 -1.6758476548448 7.31022002449644e-13 2058.44751944512 377.009450889925 5.45993612251944 9.57144998254333e-08 -1885.80139479767 546.456222281519 -3.45096517873697 0.000633556468929237 CSNK1A1 essential 9.65899371836715e-09 1 0.0011929855258242 5.45993612251944 -3.45096517873697 2.56664319408501e-08 232.422033221628 48.2742722160151 4.81461496056529 2.28143121279983e-06 -133.453154162822 69.78118362373 -1.91245185639756 0.0567136320363421 HMGXB3 other 0.000292237994078519 1 0.0266630865839916 4.81461496056529 -1.91245185639756 5.41244073483035e-11 567.217081921272 113.370333098893 5.00322321031279 9.3185933475436e-07 -521.816750479523 171.72832140674 -3.03861789485261 0.00257246667849575 ERGIC1 other 6.83320642772332e-07 1 0.0111254685976323 5.00322321031279 -3.03861789485261 0.183554511453151 17.1642352528338 274.074018693382 0.0626262764148987 0.950103203801607 698.428273133512 396.800338797399 1.76015039515911 0.079337656793666 PDGFRB other 1 1 1 0.0626262764148987 1.76015039515911 0.421389094334408 3.12297260337593 3.35863175017235 0.929834776681211 0.353157533311405 5.78125667967724 4.86257771793774 1.18892838634754 0.235349360779647 CDX1 other 1 1 1 0.929834776681211 1.18892838634754 9.97295844140774e-10 579.184265709945 115.023218254981 5.0353682890877 7.97995036712327e-07 -406.000035280906 174.232038080886 -2.3302260580366 0.0204155879262457 ATP6V0E1 other 1.20533175722854e-05 1 0.00955200058944656 5.0353682890877 -2.3302260580366 1.91862299581017e-11 43.3021834408328 8.58032841568404 5.04668135565539 7.55468563673626e-07 -41.6187893183332 12.9970985853827 -3.20216000862995 0.00150110664683916 BNIP1 essential 2.45104087714749e-07 1 0.00905277979850106 5.04668135565539 -3.20216000862995 0.124787192198469 152.623254589004 100.553802992097 1.51782677579085 0.130045363579281 -115.94230826567 152.314413540923 -0.761203786104713 0.447095933870231 STC2 other 1 1 1 1.51782677579085 -0.761203786104713 0.139471542740037 12.7376144144873 59.641550372012 0.213569471870482 0.831018814397219 -161.028692817602 90.342358988634 -1.78242736430937 0.0756275726257431 CPEB4 other 1 1 1 0.213569471870482 -1.78242736430937 0.00101284030474691 69.8502295523115 21.3706521132092 3.26851184429403 0.00119869717336708 -19.8869485647194 32.540745388387 -0.611139920962492 0.541540822885474 HRH2 other 1 1 1 3.26851184429403 -0.611139920962492 5.45462513456393e-07 718.842070927839 137.880325543422 5.2135217123596 3.33127867127986e-07 30.8563623946057 209.515064198709 0.147275149462956 0.883007592576002 DBN1 other 0.00575299312942458 1 0.00405749742161887 5.2135217123596 0.147275149462956 4.8885011968667e-15 53.4108858325692 9.81974516977848 5.43913155678907 1.06526011187552e-07 -64.7857303270073 14.9523667156182 -4.3328077460364 1.97336286911401e-05 ZNF346 other 6.72413339629014e-11 0.288209647034102 0.00132497052715077 5.43913155678907 -4.3328077460364 0.0049319190719653 7.36153380934699 2.61624595762507 2.813777423293 0.00519924344836559 -2.50458513627853 3.9837152899912 -0.628705857211012 0.52999014559513 UNC5A other 1 1 1 2.813777423293 -0.628705857211012 1.44879603045833e-22 143.469729130731 13.3435677322076 10.7519766834499 3.32436010578052e-23 82.9229101830598 83.9722646430463 0.987503558889983 0.324146600186884 EHHADH other 2.136829265323e-18 1 4.98753746670252e-19 10.7519766834499 0.987503558889983 1.25755158336223e-06 589.428998267296 113.163481922133 5.20865024878678 3.45540265626286e-07 -791.503388863374 667.001326905849 -1.18665939172127 0.236261901696597 SMC4 essential 0.0129322543511463 1 0.00420557057293753 5.20865024878678 -1.18665939172127 5.97611047546482e-11 59.5266209996021 40.0283912745649 1.48711000128119 0.137970407368517 -293.133996166695 57.7445821234289 -5.07638960032859 6.53973547251187e-07 SELENOK other 7.53468008746604e-07 0.00981941281197658 1 1.48711000128119 -5.07638960032859 2.62140616960203e-26 55.6104164401438 14.6068949510523 3.80713468717988 0.00016847842991674 -157.950584909401 21.0717697667081 -7.49583858679738 6.51356476810022e-13 ACTR8 essential 3.9245071765112e-22 9.98464343302083e-09 1 3.80713468717988 -7.49583858679738 2.02636783064938e-27 112.300072342504 9.29725493697722 12.0788418843784 6.24646975573489e-28 70.6276609001713 57.8093468573511 1.22173428242409 0.222707374236219 TBCCD1 other 3.04441502876763e-23 1 9.46152773901164e-24 12.0788418843784 1.22173428242409 1.83832807284835e-19 407.204672825447 42.2086457006813 9.64742331969383 1.74280632521652e-19 -120.475936399075 166.046956567582 -0.725553415066906 0.468646193096406 TIMMDC1 other 2.65546490122944e-15 1 2.57970192258549e-15 9.64742331969383 -0.725553415066906 3.14108628072712e-22 119.470395032703 20.5986701108587 5.79990816832993 1.61832411428616e-08 -176.855620938071 33.1885764465017 -5.32881008690304 1.89065388105564e-07 CRBN other 4.62462133111453e-18 0.00285261857573676 0.000207792816274343 5.79990816832993 -5.32881008690304 9.7748926556263e-09 296.77781639354 49.3620033357597 6.01227252416927 5.00132115957051e-09 432.861751525624 306.130191930558 1.41397929030082 0.158343163829849 BCL6 og 0.000113554927980411 1 6.52522371689165e-05 6.01227252416927 1.41397929030082 0.000341277439264224 13.1278953123805 3.28610738797182 3.99496844212477 8.04440041291073e-05 -12.724643313978 19.803564187215 -0.642543089399684 0.520983597675884 CLDN16 other 1 1 0.841846503211108 3.99496844212477 -0.642543089399684 1.62893120022418e-07 24.8300839214461 4.68409732804114 5.30093253459998 2.16336256033407e-07 -12.6105217248423 19.386972436241 -0.650463694953672 0.515863893808823 ARL6 other 0.00177602368760442 1 0.00265812357788248 5.30093253459998 -0.650463694953672 3.73319064551178e-08 61.0653230368215 10.8908509964859 5.60702952014726 4.45119862494527e-08 -61.0794664082984 44.6665548405394 -1.36745416400153 0.172442670430194 NPHP3 other 0.000421290564346004 1 0.000561830290440592 5.60702952014726 -1.36745416400153 0.184772357795397 -17.2869997939477 13.4832084476479 -1.2821132196442 0.200730996050586 -81.3829411283197 53.0818343388893 -1.53315992451859 0.126224486559517 CD86 other 1 1 1 -1.2821132196442 -1.53315992451859 3.8133122582044e-06 314.980814300174 64.3937131744299 4.89148394730637 1.58786935082253e-06 -212.641911221398 264.300250249838 -0.804546764599701 0.421678593064528 AMOTL2 other 0.0377441647317071 1 0.0187257432542501 4.89148394730637 -0.804546764599701 1.51268734107442e-13 197.158517667337 28.2048891239144 6.99022487913876 1.62808545812076e-11 -234.1915761191 117.11751076166 -1.99962904433387 0.0463934083726026 NIT2 other 2.0265472308374e-09 1 2.2433389527446e-07 6.99022487913876 -1.99962904433387 3.20038640326245e-08 473.867265629632 80.7606723256381 5.86754978610052 1.10426759392259e-08 -107.197818668337 317.945439034927 -0.337157906695309 0.736218897150939 FAM162A other 0.000362571775625603 1 0.000142483647643832 5.86754978610052 -0.337157906695309 1.11956102600221e-19 104.265499675977 17.5880297157559 5.92820806884201 7.94954088410512e-09 -134.980170628509 29.9561854662749 -4.50591984685341 9.28722269397552e-06 OGG1 other 1.6217961022668e-15 0.136819364727647 0.000103049898480655 5.92820806884201 -4.50591984685341 1.24938972567664e-24 604.947115126779 53.4823179556178 11.3111611136375 3.51781679700704e-25 45.9426511308883 210.553708548143 0.218199201750862 0.827412988194423 KPNA1 other 1.85959166769711e-20 1 5.30240525812871e-21 11.3111611136375 0.218199201750862 1.80347363269051e-12 317.710389123589 41.4446890111348 7.66588908504611 2.15917320747283e-13 78.1868785548336 185.066865009317 0.422479078309871 0.672959987443085 PCCB other 2.36128802728168e-08 1 3.05652559249854e-09 7.66588908504611 0.422479078309871 2.69985217437342e-06 253.051030517128 62.9613996985788 4.01914556742042 7.3029257808352e-05 -204.619797351608 141.018569434529 -1.45101314083751 0.147765027009284 UBE3A other 0.0270201205611292 1 0.768194762886055 4.01914556742042 -1.45101314083751 9.35928312082759e-26 228.471357442486 19.6122701958408 11.649409026138 2.33180788888996e-26 -39.6551116596577 89.197448595991 -0.444576748369459 0.656928072211397 ARMC8 other 1.39958719788856e-21 1 3.52289535853495e-22 11.649409026138 -0.444576748369459 0.000513300179261259 111.204184802918 28.4819495288222 3.90437405593972 0.000115380489136865 -9.0974633810008 129.537131787502 -0.0702305451376264 0.944054306949085 CEP70 other 1 1 1 3.90437405593972 -0.0702305451376264 0.00354107299528892 696.586606043859 205.896612509935 3.38318633586187 0.00080608974586675 580.679681730263 958.826556072072 0.605614934268273 0.545202466311978 RBP1 other 1 1 1 3.38318633586187 0.605614934268273 7.32680256784126e-18 364.726577849165 38.7679321366455 9.40794511720696 1.03320778399442e-18 9.53873866306669 187.886429376213 0.0507686409004393 0.959541653583813 SLC25A36 other 1.04319014960924e-13 1 1.52460140606217e-14 9.40794511720696 0.0507686409004393 7.01524032673601e-17 375.339554849609 41.0776301919606 9.13732250608428 7.62607083911563e-18 90.7451579119933 205.360815626631 0.441881561655745 0.658874317065298 RNF7 other 9.87044313971756e-13 1 1.11904963493183e-13 9.13732250608428 0.441881561655745 1.06769113379769e-11 340.817540987979 46.0707078040243 7.39770577082838 1.23502642517556e-12 153.252836988192 236.693212020562 0.647474575548361 0.517790521437547 TFDP2 other 1.37208987604341e-07 1 1.73175405338117e-08 7.39770577082838 0.647474575548361 4.9080212888498e-08 231.141541544566 40.1484514650695 5.75717202307708 2.01513283433916e-08 -186.323806934331 205.960217801169 -0.904659205178184 0.366330811379975 XRN1 other 0.000550238266692951 1 0.000257957154123755 5.75717202307708 -0.904659205178184 5.17857202176362e-06 62.337021751045 39.7676181603885 1.56753219414929 0.117978641361579 -210.02872343582 60.8518367234444 -3.45147714095049 0.000632399154612609 KAT2B other 0.0506826843770006 1 1 1.56753219414929 -3.45147714095049 0.032087755819736 27.5185409886779 10.9135734600877 2.52149683962971 0.0121818805915679 -58.1556474316607 71.8057981506036 -0.809901831460553 0.418611892074256 BCHE other 1 1 1 2.52149683962971 -0.809901831460553 4.15239074536664e-21 283.128958601031 27.1383057594638 10.4328162970268 4.39318070377103e-22 94.6456529195239 191.57963312768 0.494027738618993 0.621630902298908 PDCD10 other 6.07079526972603e-17 1 6.57219833284146e-18 10.4328162970268 0.494027738618993 0.736737400695661 179.275252799826 256.230564736518 0.699663808586514 0.484645572665295 247.852758891964 369.635811403746 0.670532321937929 0.50300214661205 WNT5A ts 1 1 1 0.699663808586514 0.670532321937929 0.000884644025049171 164.553715588668 57.5704659447835 2.85830091676682 0.00453930237756348 -47.1272059043174 80.9068813816234 -0.58248699121187 0.560650178670944 PFKFB4 other 1 1 1 2.85830091676682 -0.58248699121187 0.0223066665813604 18.940745808543 7.20493221329331 2.62885829426636 0.00898327293356081 38.0883282632689 43.2214788557975 0.881236118512866 0.378855593022418 FGF12 other 1 1 1 2.62885829426636 0.881236118512866 9.3255701351639e-10 278.976912598214 71.6337160566426 3.89449169965746 0.000119961930883491 -252.78380763242 101.050019972912 -2.501571080344 0.0128665989969673 PRKAR2A other 1.12886026486159e-05 1 1 3.89449169965746 -2.501571080344 0.104925147732752 100.056294361257 47.5530272164857 2.1040993648154 0.0361496519188344 98.6751220313398 290.048090041859 0.340202626457906 0.733927149156579 HES1 other 1 1 1 2.1040993648154 0.340202626457906 1.04247568777466e-10 119.268537599281 55.1107302257136 2.16416180861332 0.0311936512417411 -350.443835302442 77.8241268281716 -4.5030230287863 9.40706479736049e-06 USP4 other 1.3022606291681e-06 0.13856606446512 1 2.16416180861332 -4.5030230287863 2.10512718177079e-18 746.900102103275 77.8934090775818 9.58874583803827 2.63019697679982e-19 413.823800479397 486.581477849932 0.850471748961693 0.395698759336836 ACAP2 other 3.01222648439582e-14 1 3.89163944687302e-15 9.58874583803827 0.850471748961693 1.95168807216671e-19 529.896666462666 53.2545127560447 9.95026785598596 1.83619656486444e-20 -216.431778059195 384.506551657624 -0.562881899219007 0.573915704098857 ECT2 essential 2.81843274501595e-15 1 2.73226048851829e-16 9.95026785598596 -0.562881899219007 1.0502123725755e-07 715.642029345822 284.293234674521 2.5172671807162 0.0123197550846675 -1252.39681634571 404.567663745907 -3.09564240688374 0.00213911093234277 GNAI2 other 0.00115764909828997 1 1 2.5172671807162 -3.09564240688374 8.69147180091357e-31 887.460238918446 73.8151698865241 12.0227351678894 1.09655074051589e-27 -618.564837166934 301.452471173992 -2.05194813881592 0.0409957915643741 TFG other 1.31484585404221e-26 1 1.66039713128917e-23 12.0227351678894 -2.05194813881592 0.0251757298747622 37.3031838823797 42.3821214877578 0.880163204976768 0.3794376683793 -103.587123968186 60.3125005578407 -1.71750670275799 0.0868632468225517 HYAL1 other 1 1 1 0.880163204976768 -1.71750670275799 8.57406079664153e-17 83.9586168278874 23.2238691824345 3.61518643462693 0.000348995839929376 -170.790970902796 33.0490681884669 -5.1677998886031 4.19928771707787e-07 TUSC2 other 1.2052557261839e-12 0.00631950808543048 1 3.61518643462693 -5.1677998886031 1.41580358747938e-14 23.1093580003058 19.1037812427831 1.20967455115912 0.227305132756934 -173.835698987517 27.18591652367 -6.39432916805152 5.77087214630611e-10 NPRL2 other 1.93257189690935e-10 8.81500720348258e-06 1 1.20967455115912 -6.39432916805152 4.52852455556842e-06 916.715124548509 248.156314919726 3.6941035526138 0.000259565513859315 -2397.75987687793 1014.06267190901 -2.36450856865095 0.0186525105934684 RPL24 essential 0.0445335104794598 1 1 3.6941035526138 -2.36450856865095 2.87767783715064e-15 45.3706215629971 21.367704763332 2.12332686479529 0.0345008582749781 -180.978270042675 30.4076261456258 -5.95173951350061 7.02577615605992e-09 CYB561D2 other 3.97061987970045e-11 0.000106848003781359 1 2.12332686479529 -5.95173951350061 8.60826272749610e-09 15.5159464170678 17.0301070773935 0.911089187317228 0.362934177986593 -114.961647442131 24.4215674319428 -4.70738202052356 3.7421150114094e-06 C3orf14 other 0.000100269044249875 0.0556265396446008 1 0.911089187317228 -4.70738202052356 9.19422940673841e-38 863.934013229025 57.9245634224651 14.914812683663 2.53618843247837e-38 422.652141363119 382.69066551187 1.10442239503751 0.270263688410557 FXR1 other 1.40221192682167e-33 1 3.8750423059837e-34 14.914812683663 1.10442239503751 0.00728862452892951 83.1287796996484 27.8382856857491 2.98613142483136 0.00304686611937303 -35.0698321299773 115.333636824177 -0.304072888843698 0.761273126810111 CBLB other 1 1 1 2.98613142483136 -0.304072888843698 1.67707334471972e-08 256.499851866826 43.7369729659819 5.86460000481352 1.13123633316817e-08 -96.5315994200143 176.666618929201 -0.546405427381272 0.585171645532179 BBX other 0.000192712498041743 1 0.000145895549888699 5.86460000481352 -0.546405427381272 0.000967860823037094 108.217593689875 29.5201413223481 3.66589009544983 0.000288899960154066 -5.17754370799987 119.240615069263 -0.0434209745143666 0.965393295599078 IFT57 other 1 1 1 3.66589009544983 -0.0434209745143666 2.56771267374978e-09 252.468401401027 39.1117973807912 6.45504472584071 4.1669469401532e-10 -279.757335328323 262.487369848985 -1.0657935103288 0.287346369195402 GNB4 other 3.05917287950549e-05 1 5.59579304593173e-06 6.45504472584071 -1.0657935103288 0.0022537899094869 133.072181235231 39.7593503090872 3.34694053601818 0.000917355265833647 -277.268737033626 255.055801256477 -1.08709049418881 0.277838620113244 IQCG other 1 1 1 3.34694053601818 -1.08709049418881 3.05529600969185e-05 215.952828510646 78.7685911285103 2.74161090628524 0.00646892084785496 -177.277499507889 110.373962664473 -1.60615325597032 0.109258349229963 GBE1 other 0.279040184565157 1 1 2.74161090628524 -1.60615325597032 2.53863498693336e-19 370.448844575998 37.6196873297357 9.84720689805375 3.70738010668805e-20 109.87655398037 149.636138568446 0.734291562396281 0.463308758741194 UMPS essential 3.66325028614484e-15 1 5.51064979058112e-16 9.84720689805375 0.734291562396281 4.22273720576403e-29 529.934489563422 41.717706817056 12.7028671994684 3.2517175667479e-30 54.4704214408465 256.062792804605 0.212722906144399 0.831678544090283 NCBP2 essential 6.36915452745388e-25 1 4.94065967091676e-26 12.7028671994684 0.212722906144399 1.25428769917778e-18 168.608594767276 17.7260945879172 9.51188621560256 4.68503852175363e-19 -5.0533125708397 70.8849269904787 -0.0712889578276418 0.94321231598693 SNX4 other 1.7991502757006e-14 1 6.92495543900404e-15 9.51188621560256 -0.0712889578276418 6.00933096047158e-10 66.7481958316494 10.8611986663006 6.14556439693451 2.36737560458918e-09 -57.3148218585398 44.2801479554977 -1.29436834574587 0.19647149676783 C3orf52 other 7.32657630700695e-06 1 3.12020104684854e-05 6.14556439693451 -1.29436834574587 6.01993790842229e-06 119.542859959746 66.9687460459178 1.78505447717029 0.0752055348281887 -274.632493273679 93.1244054102195 -2.94909258280796 0.00342331326034632 FRMD4B other 0.0585920556626741 1 1 1.78505447717029 -2.94909258280796 4.5942787353705e-08 165.267654211137 28.6953084127977 5.759396338721 1.98125368099941e-08 -52.9873273008136 114.507296846868 -0.462741927893681 0.64386386969419 SLC41A3 other 0.000515615902470631 1 0.000253699533851974 5.759396338721 -0.462741927893681 2.55362061913308e-07 1114.63655496211 207.984719910183 5.35922329026602 1.60212123148053e-07 -633.952792881915 839.775106931864 -0.754907817163187 0.450859521181642 PLXNA1 other 0.0027553566480446 1 0.0019787799330016 5.35922329026602 -0.754907817163187 6.21267470360377e-22 661.455284032754 63.1534361047787 10.4737813938631 2.87858956116478e-22 81.9305421759282 259.430971687912 0.315808639357401 0.752353633974535 ATP6V1A essential 9.12766167453465e-18 1 4.30896071410756e-18 10.4737813938631 0.315808639357401 0.00184792758189618 70.3657383078095 23.9530827291977 2.93764853164545 0.00354717362371585 -142.044219438834 96.3023833913606 -1.47498134975107 0.141200734188017 ABTB1 other 1 1 1 2.93764853164545 -1.47498134975107 6.66835077048657e-06 308.431207752309 62.3287099442692 4.94846127937014 1.2114449544236e-06 103.106303939345 250.590013369147 0.411454161932055 0.681014980266873 PODXL2 other 0.0646496607198673 1 0.0143895431686435 4.94846127937014 0.411454161932055 0.286165994979938 493.79619725158 329.890811170282 1.49684738262289 0.135424821696248 1007.27578029702 1297.77594815253 0.776155376997809 0.438234126729301 UPK1B other 1 1 1 1.49684738262289 0.776155376997809 7.72715950850571e-07 8.84920236917371 9.07177294145364 0.97546559269987 0.330068488801318 -52.513967010477 13.0954730382717 -4.01008553543689 7.56454472014155e-05 CSPG5 other 0.00806406366307656 1 1 0.97546559269987 -4.01008553543689 2.87664012258894e-15 87.6659427640853 24.273601132564 3.61157548421927 0.000353371293386125 -166.032053801636 35.0399300362469 -4.73836716083293 3.2492644535847e-06 KLHL18 other 3.96947570516048e-11 0.0483230609537116 1 3.61157548421927 -4.73836716083293 1.62128340789874e-23 390.144495195243 72.3821192275034 5.39006731716412 1.37207449787738e-07 -566.711090931271 104.486531675125 -5.42377167512191 1.15493246224074e-07 SCAP essential 2.40225562548356e-19 0.00174521844369198 0.00169917705817134 5.39006731716412 -5.42377167512191 0.0388929497994741 1.29035856833528 1.96798007476223 0.655676642707462 0.512503317703726 20.1749418154538 7.89650280056479 2.55492112457818 0.0110836001224258 EFCC1 other 1 1 1 0.655676642707462 2.55492112457818 5.82110560439485e-10 32.6290747464323 4.84205270617436 6.73868640562818 7.44650625674633e-11 29.7153541506974 19.4286940427523 1.52945710531596 0.127139052324078 KIAA1257 other 7.1029130584826e-06 1 1.01399075698115e-06 6.73868640562818 1.52945710531596 1.05546648325398e-05 32.5558492125263 6.76409882339649 4.81303571436866 2.29531914233508e-06 0.0822693977926189 27.4354553912319 0.00299865253262432 0.997609293504035 NEK11 other 0.100512073200276 1 0.026818508859043 4.81303571436866 0.00299865253262432 1.84201679715404e-18 485.82922406114 50.6918404405114 9.58397288082836 2.7264003157392e-19 93.3910455885135 205.315340845242 0.454866378732544 0.649513801368481 MRPL3 essential 2.63758385184487e-14 1 4.033163987073e-15 9.58397288082836 0.454866378732544 2.33539234479251e-06 82.6445377166755 16.7048172235367 4.94734761899887 1.22141788386572e-06 188.46047178317 90.0721413598419 2.09232809321433 0.0372017230460139 PLSCR4 other 0.0234776992421991 1 0.0145031159530216 4.94734761899887 2.09232809321433 2.46041748851029e-24 35.9463135626421 18.1814908363491 1.97708284134637 0.0488929912244921 -217.27807333699 25.8001406564714 -8.42158483668926 1.28051240173269e-15 HEMK1 other 3.65642642967514e-20 1.96597069038019e-11 1 1.97708284134637 -8.42158483668926 0.000118058973664042 62.9933244534986 28.8365444384227 2.18449629386122 0.0296534047740107 -80.9798479981198 40.9200163646915 -1.97897887616669 0.0486780322652877 CISH other 1 1 1 2.18449629386122 -1.97897887616669 3.70958632656981e-12 388.036402099821 74.8862865766565 5.18167504143248 3.90776469903765e-07 -201.237824179269 106.266133196068 -1.89371550584203 0.0591673944033673 MAPKAPK3 other 4.82283318317341e-08 1 0.00474676177992104 5.18167504143248 -1.89371550584203 1.08109937109262e-06 71.9892549427262 18.7510770706386 3.83920639179978 0.000148770063568716 -29.9757711452734 26.859788190043 -1.1160092154556 0.265255515756277 ACVR2B other 0.0111666754040157 1 1 3.83920639179978 -1.1160092154556 4.68577554664834e-18 131.153339463847 48.3634650322754 2.71182677618987 0.00705290898155358 -435.00250684685 69.277749859903 -6.27910848326532 1.1087790455006e-09 WDR48 other 6.6823845070752e-14 1.69199682343392e-05 1 2.71182677618987 -6.27910848326532 4.38556215899601e-18 196.128265063353 20.5937543240466 9.52367703223212 4.48350083417067e-19 18.091499377091 124.714539711332 0.145063273448037 0.884753103922897 COMMD2 other 6.2577586446714e-14 1 6.6279592831545e-15 9.52367703223212 0.145063273448037 1.61101828932291e-24 156.508935889491 29.2014353324457 5.35963161083366 1.59880269874338e-07 -238.019219159187 41.8292967875906 -5.69025150883721 2.866553995277e-08 GORASP1 other 2.3962286035389e-20 0.000434655582303851 0.00197500097375769 5.35963161083366 -5.69025150883721 1.34505520834329e-12 190.635475996745 40.9245452917412 4.65821854922886 4.68937773211611e-06 -158.996658142509 58.0119505579468 -2.74075697530099 0.00647519225971898 RRP9 essential 1.76740254376308e-08 1 0.0537637156987112 4.65821854922886 -2.74075697530099 9.13187415898251e-17 1349.70386916945 159.74681795006 8.44901880669319 1.06751175650075e-15 3075.39093342836 1059.47126961412 2.90276010462133 0.003957352260389 ABCC5 other 1.2833935943034e-12 1 1.54618402811569e-11 8.44901880669319 2.90276010462133 9.27811937085965e-07 33.7072423402193 9.45280990984163 3.56584366571527 0.000418604103515699 241.899091257121 57.2474070159407 4.22550302042088 3.12060457942147e-05 AADAC other 0.0096326349261049 0.453361433298351 1 3.56584366571527 4.22550302042088 2.70135838916527e-07 187.961413281592 68.2892489230134 2.7524305252426 0.00625403481125906 -261.337898675776 96.8023591690497 -2.69970588443399 0.0073101617113828 ABHD14B other 0.00291071366432558 1 1 2.7524305252426 -2.69970588443399 1.12513176890187e-06 144.592907262659 52.6411038460983 2.74676814691029 0.00635935999264884 -182.525774143894 75.405209741805 -2.42059898472374 0.0160512504469739 EIF1B other 0.0116068593279917 1 1 2.74676814691029 -2.42059898472374 6.94659898806165e-13 189.767509544972 65.343566186626 2.90414987457192 0.00393946409213116 -426.948991407292 92.6267525729469 -4.60934859041997 5.85061429033122e-06 ABHD14A-ACY1 other 9.18131988252109e-09 0.0866534482540957 1 2.90414987457192 -4.60934859041997 1.54091391339684e-05 89.2764720445638 18.6887851343532 4.77700778315752 2.71768227825238e-06 -32.7256933468483 115.146099270447 -0.284210177801894 0.776433708441799 ARHGEF26 other 0.144645589050561 1 0.031632432442468 4.77700778315752 -0.284210177801894 2.29856059234882e-16 384.21839428588 44.032806503021 8.72573030882145 1.56379302765452e-16 464.353214943663 288.076576975269 1.61190895774746 0.107983198108251 KLHL24 other 3.21890425352528e-12 1 2.2781336826871e-12 8.72573030882145 1.61190895774746 0.04863125044278 12.1922818633976 5.4117131801546 2.25294309907409 0.0249505204356625 32.5427337235164 31.1668968938106 1.04414417111827 0.297219317255241 PLCH1 other 1 1 1 2.25294309907409 1.04414417111827 0.00099532947057433 14.9661329432889 34.1120303309493 0.438734745428225 0.66114981355883 -143.707870206755 48.648217953262 -2.95402126229617 0.00336907765546676 VIPR1 other 1 1 1 0.438734745428225 -2.95402126229617 0.0017500374473738 -13.8503718601105 11.2806681389527 -1.22779712065853 0.220431175779789 -56.2097129050981 15.9736952268621 -3.51889228552284 0.000496550018575744 DNAH1 other 1 1 1 -1.22779712065853 -3.51889228552284 9.23111365256369e-12 665.970316085249 89.6801232595596 7.42606379072141 1.06226173676298e-12 111.816092272221 515.666907420056 0.216837828185737 0.82847554606172 SSR3 other 1.1878597048119e-07 1 1.49099057372052e-08 7.42606379072141 0.216837828185737 0.0109440430561562 95.1022834753446 36.742830847232 2.58832216468996 0.0100844746961813 0.779244643189343 52.4000836635701 0.0148710572332749 0.988144317573667 ZBTB47 other 1 1 1 2.58832216468996 0.0148710572332749 0.419581282057473 543.377016210672 479.124887262569 1.13410309223385 0.257605509208902 796.514550460945 678.45227166194 1.1740170734631 0.241266667734006 TNNC1 other 1 1 1 1.13410309223385 1.1740170734631 2.39328641253748e-11 87.3857016201678 57.8979462693543 1.50930572241077 0.132207385317357 -435.593949750469 82.5700458703662 -5.27544759311803 2.44525700982741e-07 NKTR other 3.05000420413777e-07 0.00368671399371679 1 1.50930572241077 -5.27544759311803 1.09934243909084e-21 60.1800202373287 6.13561910930928 9.80830445390922 5.15294274508089e-20 138.515132002576 40.3536344060399 3.43253176675069 0.000677082530160672 CLCN2 other 1.6132850293658e-17 1 7.65469644781766e-16 9.80830445390922 3.43253176675069 9.4637393200342e-09 154.813943350701 83.6615370233821 1.85047931055143 0.0651718350697239 -469.107417620171 116.88861574231 -4.01328576475195 7.47258267560485e-05 FOXP1 other 0.000110006505856078 1 1 1.85047931055143 -4.01328576475195 1.4193735631379e-33 3885.70191389175 285.11998065613 13.6283044946545 1.26216006328707e-33 3644.38346281487 1875.21866274223 1.94344453541514 0.0528445082659033 EIF4G1 essential 2.15489294355597e-29 1 1.92239599239253e-29 13.6283044946545 1.94344453541514 3.36653100050378e-21 248.990558515459 64.1674944337741 3.88032228330868 0.000126682154291802 -566.477063066173 92.5674261193753 -6.11961557984385 2.73947759848679e-09 SPCS1 other 4.92523485373703e-17 4.17414201681433e-05 1 3.88032228330868 -6.11961557984385 3.40606849736959e-11 67.9782719002576 21.8403791339884 3.11250420531704 0.00202242544701776 -120.2613725277 31.5067262598383 -3.81700629687436 0.000162163602734765 NEK4 other 4.32332274371122e-07 1 1 3.11250420531704 -3.81700629687436 0.00532675966218469 55.9690259778919 18.8597449399039 2.96764490486143 0.00322716193840905 6.25634893859124 33.1186938638209 0.188906874296324 0.850285557490349 SLC4A3 other 1 1 1 2.96764490486143 0.188906874296324 8.56919263362474e-10 74.2293157379225 20.0897319368892 3.69488831265194 0.000259318249305649 -139.357826833353 38.076382910022 -3.65995444374715 0.000295683258049545 INO80D other 1.03927168260601e-05 1 1 3.69488831265194 -3.65995444374715 0.00123996573862587 161.999457636285 120.96130816946 1.33926674643211 0.181449389018471 -601.993486312901 228.023410588332 -2.64005123315924 0.00870210509819338 EEF1B2 essential 1 1 1 1.33926674643211 -2.64005123315924 0.571802077764262 147.806531994892 142.457627775117 1.03754733462373 0.300271618751148 162.670731058456 268.554206356245 0.605727734693043 0.545129003523014 ADAM23 other 1 1 1 1.03754733462373 0.605727734693043 0.0415594533323285 99.460436645582 39.3551758248099 2.52725174163448 0.011977211815027 -6.41781269128747 162.851337941059 -0.0394090264926793 0.968588858314793 DGUOK other 1 1 1 2.52725174163448 -0.0394090264926793 0.00126781786873014 428.514039520976 117.091866887135 3.65963965656147 0.000295317422154503 -123.210404470044 484.525015704933 -0.254291110833124 0.79943399200077 MOB1A other 1 1 1 3.65963965656147 -0.254291110833124 4.19242335634887e-05 155.737130981563 36.5413732411059 4.26193974577758 2.70194168438465e-05 -119.816020699374 121.438325144593 -0.986640918809715 0.324598192021825 KANSL3 essential 0.377276177837835 1 0.294268468846332 4.26193974577758 -0.986640918809715 3.56564733802285e-12 128.691762966421 19.4930125295341 6.60194327436249 1.79907346753685e-10 -175.928472303282 64.5432406859938 -2.7257458787851 0.00678643198112717 LMAN2L other 4.63855062203393e-08 1 2.43216742076307e-06 6.60194327436249 -2.7257458787851 0.000347471413669503 251.17116130146 62.3419960854947 4.02892395291624 7.00563243668535e-05 145.373222105378 257.97057844775 0.563526364053266 0.573471182774259 RTKN other 1 1 0.737903264556068 4.02892395291624 0.563526364053266 1.52789546060218e-05 204.937849427317 45.6276656544128 4.49152606183123 9.88750982385377e-06 -143.133478418761 148.44289481728 -0.964232599983621 0.335657420425826 TTL other 0.143499941659757 1 0.111007072792406 4.49152606183123 -0.964232599983621 0.957063944681111 33.7228119795397 134.055580208703 0.251558435143384 0.801543861556657 84.5922188454903 437.722686214999 0.193255276707181 0.846881652976031 IL1A other 1 1 1 0.251558435143384 0.193255276707181 0.243450366919974 -351.546397330685 227.546181421035 -1.54494527280249 0.123347839701511 -511.159577960137 394.413381129794 -1.29599958423298 0.195909583180138 CCL20 other 1 1 1 -1.54494527280249 -1.29599958423298 0.000104595178157884 67.2304833615197 38.6667090789397 1.73871749013514 0.0830553292796161 -208.724110661425 72.7370529944417 -2.86957062554314 0.00438637229584841 PIKFYVE other 0.899100151445171 1 1 1.73871749013514 -2.86957062554314 0.43549025358096 21.2040183842701 18.9893529373494 1.11662669361234 0.265041585704987 -32.3759318452631 64.9956005340207 -0.498124974294476 0.6187585085628 KCNIP3 other 1 1 1 1.11662669361234 -0.498124974294476 2.25301896292436e-05 56.8114235301821 13.9985894645132 4.05836771441868 6.29434277830894e-05 -85.9100823299702 47.0880850441925 -1.82445479040702 0.0690680331634305 FAHD2A other 0.208336663501615 1 0.665752635661736 4.05836771441868 -1.82445479040702 1.90732622239178e-11 2960.47543302485 623.609668758746 4.74732125131653 3.11781786645596e-06 -3005.00333755479 1086.80290737644 -2.7649938338948 0.0060236732908775 NCL essential 2.43679998172774e-07 1 0.0361510981615569 4.74732125131653 -2.7649938338948 0.00204719638153603 83.5677928916188 47.8198630690423 1.74755399803139 0.0815314240487866 -436.385081175956 157.190393957754 -2.77615616443608 0.00583503628233881 ACTR1B other 1 1 1 1.74755399803139 -2.77615616443608 1.22636622416025e-05 174.167652957545 36.424957771034 4.78154714831398 2.65766214391494e-06 -1.12034797154572 118.899848107135 -0.00942261903090263 0.992487820523808 SLC35F5 other 0.116136881427975 1 0.0309591063144652 4.78154714831398 -0.00942261903090263 0.0624321731218073 -36.1432925975372 16.2691406066259 -2.22158585210193 0.0270332408683129 23.9707523829974 53.4788779636889 0.448228408966865 0.654301469150586 ZAP70 other 1 1 1 -2.22158585210193 0.448228408966865 8.91121635671184e-08 1090.83744262491 195.356035845481 5.58384304791955 5.02735922424926e-08 -539.588657002003 635.375454966215 -0.849243786149552 0.396380527572306 ACTR3 other 0.000986738987178702 1 0.000633346715070922 5.58384304791955 -0.849243786149552 0.0389192159281996 232.349456429115 93.3843053915756 2.48809963788707 0.0133593833702794 -69.0280918969648 296.742856676457 -0.232619220122381 0.816208168855976 STEAP3 other 1 1 1 2.48809963788707 -0.232619220122381 0.111114262827217 40.6418889238282 19.3383126890262 2.10162538880091 0.0363800364032977 24.675760987237 61.4504345947823 0.401555516245806 0.688283460931588 EPB41L5 other 1 1 1 2.10162538880091 0.401555516245806 0.01280178077105 507.247336936802 176.199420894087 2.87882522180199 0.00426467118214393 -142.901785298961 550.204813016846 -0.259724709632058 0.795245800264897 TFCP2L1 other 1 1 1 2.87882522180199 -0.259724709632058 1.26112310871312e-05 199.920079031754 49.4970464913134 4.03903047158257 6.72921356255123e-05 -328.656857023407 166.384182261573 -1.97528907229129 0.0490970924435489 SF3B6 other 0.119340079777523 1 0.709864738713529 4.03903047158257 -1.97528907229129 0.732205303877063 7.00729038227685 35.3019373720429 0.19849591563284 0.842783522350689 -85.7749218489698 118.667362969373 -0.722818133837757 0.470321226309036 TP53I3 other 1 1 1 0.19849591563284 -0.722818133837757 0.00542139778632519 12.7804095864432 4.16096517003856 3.07150121766695 0.00231259228214037 -8.09077047193036 13.9941745762909 -0.578152746903548 0.563567631075308 DNAJC27 other 1 1 1 3.07150121766695 -0.578152746903548 0.0865733720220614 49.872991032773 22.8362647878377 2.18393820075754 0.0296925023599907 -3.66852938319159 76.8030163800777 -0.0477654336522021 0.961932981701324 POMC other 1 1 1 2.18393820075754 -0.0477654336522021 0.00155673743791378 27.1418386994564 23.1792132922377 1.1709559922185 0.242501495942358 -192.49662840105 60.549364747021 -3.17916842241554 0.00162375839129109 STAM2 other 1 1 1 1.1709559922185 -3.17916842241554 0.0640191149316564 12.2728652480242 5.70205293564303 2.15235905147558 0.0321165688877541 24.726588827119 19.8381852895038 1.24641384613953 0.213524141813399 OTOF other 1 1 1 2.15235905147558 1.24641384613953 0.00186814502283122 286.821926699646 100.556030311911 2.85235928476855 0.00462374665591435 -437.691423404564 265.528395315539 -1.64837897236729 0.100262508919101 GPD2 other 1 1 1 2.85235928476855 -1.64837897236729 3.84539711796544e-05 58.0771554742541 14.8634269165255 3.9073866208931 0.000113878615015364 -94.2694410701271 51.7117993352648 -1.82297739165769 0.0692397601998731 CENPA essential 0.347431629608177 1 1 3.9073866208931 -1.82297739165769 0.00973660395264771 -55.173857517391 18.3777634916863 -3.00220739821527 0.00289133494880582 -54.2987800011049 48.2448364367928 -1.12548376181653 0.261227509562838 CYTIP other 1 1 1 -3.00220739821527 -1.12548376181653 1.58679128767541e-09 299.386826944642 49.3347822368169 6.06847366848657 3.64785756300563e-09 -187.753155278528 129.512413234437 -1.44969235449784 0.148123664381379 ACVR1 other 1.90192803740775e-05 1 4.78015255056258e-05 6.06847366848657 -1.44969235449784 1.47151585927185e-05 195.143368953526 57.0599576320395 3.41997044953906 0.000707425917925475 -409.358709493519 153.964084181059 -2.65879352104041 0.0082364194209304 TANC1 other 0.13841078172311 1 1 3.41997044953906 -2.65879352104041 0.00927180574186718 12.2043910347293 3.98572831353796 3.06202281607497 0.00238490575446717 1.16885998682816 13.911293262352 0.0840223812973186 0.933091175303609 SLC30A3 other 1 1 1 3.06202281607497 0.0840223812973186 4.6614455035653e-09 148.696090436882 25.0106098709616 5.94532045416152 7.2164637005978e-09 -127.823999481763 87.2939400820271 -1.46429407770632 0.144095295735575 MPV17 other 5.49631039325384e-05 1 9.36624823700588e-05 5.94532045416152 -1.46429407770632 1.57431591156211e-12 407.853128558421 56.4164624099247 7.22932830482955 3.59281027761797e-12 -345.517879174721 200.156304757849 -1.72624029801475 0.0852693829387877 GTF3C2 essential 2.06518761278718e-08 1 5.00442543569407e-08 7.22932830482955 -1.72624029801475 9.6439028994709e-07 116.32405499017 21.7373284125468 5.3513501191355 1.66743273378518e-07 9.1218665088183 77.1204564148244 0.11828076405244 0.905919409428482 EIF2B4 essential 0.00999783413588148 1 0.00205704062403325 5.3513501191355 0.11828076405244 4.21617470638755e-12 574.537532954401 80.2873367150051 7.15601683231603 5.70457641689356e-12 -422.76891862016 284.84623014749 -1.48420050495755 0.138740052072471 NRBP1 essential 5.47512447371487e-08 1 7.9208043548567e-08 7.15601683231603 -1.48420050495755 0.00485294149108247 33.0202236763831 11.3865599451017 2.89992972729114 0.00399066657392248 77.0294919690661 40.3830943705652 1.90746878538392 0.0573549663926606 FNDC4 other 1 1 1 2.89992972729114 1.90746878538392 0.0940124491873016 38.4357395047286 17.6096492860148 2.18265218576803 0.029794938285308 15.3495238783349 52.0743648841395 0.294761614711693 0.768368932339954 ITGA4 other 1 1 1 2.18265218576803 0.294761614711693 1.37239507089321e-06 275.938160882259 65.5323856839374 4.21071441246025 3.31510761336538e-05 -425.618975024327 178.798307865424 -2.38044185152288 0.0178788648551424 PSMD14 essential 0.014072539056939 1 0.358993003451338 4.21071441246025 -2.38044185152288 1.34207937665983e-06 335.924633371131 70.249321845742 4.78189147660067 2.65341681443139e-06 -424.505484278166 249.233008801967 -1.70324744029177 0.0894926974922774 SNX17 other 0.0137697344045298 1 0.0309123058881257 4.78189147660067 -1.70324744029177 0.00112205119130461 33.0282289391473 9.32681726250061 3.54121111302786 0.000457650372899426 -24.4306031210246 36.9262237092679 -0.661605782204393 0.508701501919402 ASB3 other 1 1 1 3.54121111302786 -0.661605782204393 9.62805664616401e-08 575.389142460483 104.540286605741 5.50399430824674 7.62252787997349e-08 -455.62618475385 370.891696705369 -1.22846153958467 0.220176466181607 PPM1G other 0.00106399653996759 1 0.000954111814736282 5.50399430824674 -1.22846153958467 0.934858791743405 -0.650951262677825 1.77470986875594 -0.36679305960818 0.714018096757201 -0.424060649377164 6.21329520517649 -0.0682505233332332 0.945629237880815 PDE1A other 1 1 1 -0.36679305960818 -0.0682505233332332 0.00689230201037505 79.9225739040951 31.0597158081893 2.57319076573851 0.0105295197674915 -15.9267947385129 51.2971014168103 -0.310481378062691 0.756398313156877 REEP6 other 1 1 1 2.57319076573851 -0.310481378062691 0.0124706415250654 26.9341994102772 11.7459610060828 2.29306051640466 0.0224988837769932 -9.04237974835502 19.4159704354528 -0.465718660749708 0.641736704116363 PCSK4 other 1 1 1 2.29306051640466 -0.465718660749708 0.000343981798009202 24.7573303639593 14.0454738208584 1.76265540626997 0.0789191856509581 -51.5881768096196 23.1256869401577 -2.23077381195699 0.0263932732002671 APC2 other 1 1 1 1.76265540626997 -2.23077381195699 0.900646526781312 -49.5771785889729 108.413473405136 -0.45729720699664 0.647768711886632 -31.6155706303769 294.938559348434 -0.107193751472241 0.914702655933792 IFIH1 other 1 1 1 -0.45729720699664 -0.107193751472241 2.20924688697419e-06 726.888711822925 429.401999090158 1.69279303161862 0.0914742641543929 -2384.94877793002 707.004714051716 -3.37331382737508 0.000834508931404573 RPS15 essential 0.0222426976580562 1 1 1.69279303161862 -3.37331382737508 0.446758826400212 8.22175444073576 13.9634314918497 0.588806157392952 0.556408008397387 -37.3985371462152 37.9874773717159 -0.984496463933686 0.325617569680914 GCA other 1 1 1 0.588806157392952 -0.984496463933686 0.00139297936135759 70.2841366754034 19.1811089595341 3.66423739230512 0.000290274351233307 17.4254955817493 79.371243852611 0.219544191774387 0.826366135258741 INO80B other 1 1 1 3.66423739230512 0.219544191774387 8.49113389969632e-07 289.381672500117 53.7614372334053 5.38269970804103 1.42178695101156e-07 182.726092006341 222.464308686306 0.821372619659185 0.412045565216168 MOGS other 0.008835873936024 1 0.0017594613518768 5.38269970804103 0.821372619659185 0.0628436017234814 31.6605935994224 14.564142111101 2.17387288299599 0.0304473776700742 -47.6426914444461 60.2662795692892 -0.790536462262789 0.429800003793847 TTC31 other 1 1 1 2.17387288299599 -0.790536462262789 1.78240355115626e-05 144.711246170206 97.2494135865913 1.48804235247501 0.137730664039104 -500.726610902003 160.119873661904 -3.12719838862286 0.00192793053659181 NDUFS7 other 0.166351723429414 1 1 1.48804235247501 -3.12719838862286 1.76631141136816e-06 57.96434008758 11.0569021474128 5.2423671038043 2.88544963008267e-07 -2.28754728234429 45.7533544305604 -0.0499973676425428 0.960155678364651 PCGF1 other 0.0179139303340959 1 0.00352659653788704 5.2423671038043 -0.0499973676425428 0.00284865873949757 16.7546727225013 6.05316756397956 2.76791820900564 0.00597433696018334 42.7353646182287 16.9802696578338 2.51676595715975 0.012338514704477 GRB14 other 1 1 1 2.76791820900564 2.51676595715975 1.84981176372013e-05 202.775817820268 46.2357921943527 4.38568927223951 1.57100053024755e-05 -190.363275330927 161.320006400793 -1.18003513375754 0.238862707352883 CLIP4 other 0.172328463908167 1 0.173925468703706 4.38568927223951 -1.18003513375754 0.403291535201548 -2.29546717310438 2.69610304352771 -0.851401870049032 0.395182827671834 -12.2424983912231 11.1564483873722 -1.09734728886302 0.273314654501857 TLX2 other 1 1 1 -0.851401870049032 -1.09734728886302 0.000268958192983516 1086.56581615187 265.5409110907 4.09189609122314 5.42485309343615e-05 213.866981893614 1051.31502107602 0.203428066379876 0.838930167167234 SPTBN1 other 1 1 0.576716132363197 4.09189609122314 0.203428066379876 2.36538920225801e-05 420.014081898512 91.1850366733835 4.60617330673413 5.92837551464959e-06 -232.888121733398 377.322802179015 -0.617211894930505 0.537533889512166 AUP1 other 0.218136192232234 1 0.067571624115976 4.60617330673413 -0.617211894930505 4.05096801009302e-05 1048.92437738376 229.67617734429 4.5669707216147 7.06971429147323e-06 430.534612724736 909.472868574058 0.473389176963312 0.636258322593912 RTN4 other 0.365275785470088 1 0.0802129783510552 4.5669707216147 0.473389176963312 2.49352662773333e-09 151.243899989013 23.5110358965923 6.43288967165133 4.56113425617445e-10 -48.1685872584873 97.2884397514653 -0.49511110859152 0.620861481772274 HTRA2 other 2.97178503493258e-05 1 6.12058605836049e-06 6.43288967165133 -0.49511110859152 0.00019742652668281 52.5738640465837 12.6714754249987 4.14899309537896 4.28442942680074e-05 -15.7611900240139 52.4344430789557 -0.300588489140253 0.763923504432062 LOXL3 other 1 1 0.459847810378523 4.14899309537896 -0.300588489140253 0.2812789860759 -3.28679390391283 10.4131722281739 -0.315638100656789 0.752482968343948 -68.1152982907725 43.089606234201 -1.58078256553452 0.114915644977212 DOK1 other 1 1 1 -0.315638100656789 -1.58078256553452 4.59369842400957e-09 382.880347623155 67.1225768925704 5.70419619371818 2.69428547120378e-08 -356.30545463092 194.378571613139 -1.83304904277234 0.0677389051566794 GALNT3 other 5.41964540064649e-05 1 0.000343171140467226 5.70419619371818 -1.83304904277234 0.0980525304991377 -6.66783074097899 41.5671726168264 -0.160410976287568 0.872658556910386 -372.007149247405 172.004559329392 -2.16277493281446 0.0312988415493105 POLE4 other 1 1 1 -0.160410976287568 -2.16277493281446 0.597125686133525 -1.79151821449311 2.39696165489255 -0.747412129366507 0.455363680269626 6.36355217930404 9.91860420673279 0.641577387974049 0.521606893503784 TACR1 other 1 1 1 -0.747412129366507 0.641577387974049 0.00881241096091832 122.005930247851 42.0639163832865 2.90048908275998 0.00398373591399481 -113.891518122055 166.564905158711 -0.683766595451388 0.494617385754643 CCDC88A other 1 1 1 2.90048908275998 -0.683766595451388 0.840514968038438 -4.8360653450331 17.1178949831963 -0.282515189500835 0.777732874374919 -18.8228567012683 31.95949343045 -0.588959795067792 0.556307693163806 ACADL other 1 1 1 -0.282515189500835 -0.588959795067792 0.473881926693896 26.1164644578028 28.9993844956437 0.900586854239133 0.368485285296421 -92.579781206347 119.999173313453 -0.771503491649203 0.440977878627068 EVA1A other 1 1 1 0.900586854239133 -0.771503491649203 1.4735025904684e-07 152.336873974862 26.8592231804253 5.67167832634429 3.16372920797283e-08 -66.242191573884 110.764631440877 -0.59804461687973 0.550233180108849 MRPL19 essential 0.00161083303190006 1 0.000401508873783832 5.67167832634429 -0.59804461687973 6.51658494054527e-09 329.708853190002 69.988052582117 4.71093052350835 3.69961384198765e-06 -227.179238529109 130.728064148873 -1.73780006617705 0.0832202459152261 LANCL1 other 7.62831433140229e-05 1 0.0427083421919054 4.71093052350835 -1.73780006617705 3.44586285179637e-11 232.054894803178 33.4638101593637 6.93450308551447 2.34114549140756e-11 -55.6032021215797 87.3621523590001 -0.636467859595397 0.524936686990265 WDR75 essential 4.37245537264442e-07 1 3.21673390519399e-07 6.93450308551447 -0.636467859595397 0.0254597655229904 344.094537237414 135.394045595063 2.54143035408316 0.011511583738046 -335.557241302062 536.134014676687 -0.625883141371693 0.531837738936357 EFEMP1 other 1 1 1 2.54143035408316 -0.625883141371693 0.187435677488942 -53.5517163045949 36.6876290799531 -1.45966685903551 0.145362629939177 -189.026424967955 145.275855973991 -1.30115512795048 0.194141430977772 FANCL other 1 1 1 -1.45966685903551 -1.30115512795048 0.0161199487520136 36517.3695956081 12915.9573335238 2.82730645918333 0.00498974730879271 17102.3994410377 22661.1036766007 0.75470284612383 0.450982350339093 FN1 other 1 1 1 2.82730645918333 0.75470284612383 0.246389091203939 -865.8520012477 718.229115926917 -1.20553731677985 0.228906509423322 -2701.42805539056 1958.23702100221 -1.37952046990103 0.168719102356557 STAT1 other 1 1 1 -1.20553731677985 -1.37952046990103 0.00023657313189471 374.025902772734 99.4546913342203 3.76076681506968 0.000202134685339363 -262.177131359788 271.161185427124 -0.9668682151054 0.334356385367789 GLS other 1 1 1 3.76076681506968 -0.9668682151054 6.4254784164595e-09 98.4669941771596 15.5845203969185 6.31825629979792 8.85703929364116e-10 6.17504079008884 65.1456514904674 0.094788226824202 0.924542364623179 PAPOLG other 7.52487777351572e-05 1 1.18055476744943e-05 6.31825629979792 0.094788226824202 0.00179032123229149 7.02955409396792 8.76906428262735 0.801631036950472 0.423361274487481 -42.2440578108765 15.385361667278 -2.74573056678429 0.00637903276078656 PECR other 1 1 1 0.801631036950472 -2.74573056678429 0.00174969134850969 36.2378249606717 16.7043040959335 2.16937052585707 0.0308020840893109 -130.844738666515 53.1223755234981 -2.46308146759434 0.0143093451332013 UNC50 essential 1 1 1 2.16937052585707 -2.46308146759434 0.00283850382223584 1355.54624187924 1077.14081470878 1.25846706704335 0.2091402787443 -4319.00731023745 1889.84827420101 -2.28537251862901 0.0229447301592562 IGFBP2 other 1 1 1 1.25846706704335 -2.28537251862901 0.27696074865095 10.7536009820458 10.3990248476213 1.03409705617788 0.301879034132703 -49.4572341985111 43.4145378584505 -1.13918601091096 0.255485680220756 ELMOD3 other 1 1 1 1.03409705617788 -1.13918601091096 0.00661471857402106 5445.17889084358 1709.56413551179 3.18512700268684 0.00158939942577168 4977.0766051152 2999.43775875431 1.65933651751528 0.0980276843332715 IGFBP5 other 1 1 1 3.18512700268684 1.65933651751528 1.93827928176429e-07 469.372583270474 82.6855315766834 5.67659872676967 3.08953631279753e-08 270.128323209866 353.866677023906 0.763361855605345 0.445811794063787 USP34 other 0.00210477747206784 1 0.000392371111725286 5.67659872676967 0.763361855605345 0.267528118258194 72.8352423743833 48.3034550133598 1.50786817121546 0.132577964171433 11.5916311452438 83.3643201497743 0.13904786993306 0.889500061935461 EFHD1 other 1 1 1 1.50786817121546 0.13904786993306 1.93200668626286e-06 775.308879798473 153.257789438511 5.05885464379307 7.13272116952723e-07 -728.589058701702 656.210649943256 -1.11029752224336 0.267707059002004 CCT4 essential 0.0195422476315488 1 0.0085528459543801 5.05885464379307 -1.11029752224336 0.207354850829528 -4.0554299541652 50.6138360961507 -0.0801249276277169 0.936188456388453 -375.503174869518 211.305996048311 -1.77705877680663 0.0765173973893651 GGCX other 1 1 1 -0.0801249276277169 -1.77705877680663 8.0084830795511e-06 299.07493739675 60.6002061499855 4.93521320136338 1.29409130827053e-06 51.3139369537185 259.433007369373 0.19779263045222 0.843333686417191 EHBP1 other 0.077105675089918 1 0.0153440406421637 4.93521320136338 0.19779263045222 0.0117317860479638 81.3663619337247 27.3598739391721 2.9739304396878 0.00316498180436397 64.8083742837538 116.763257883505 0.555040818991306 0.579256942464438 OTX1 other 1 1 1 2.9739304396878 0.555040818991306 0.0140976554447659 19.7683409257054 25.734899415068 0.768153028572979 0.442969921561557 -202.33349032562 76.6476219744977 -2.63978822973713 0.00870739129087422 TXNDC9 other 1 1 1 0.768153028572979 -2.63978822973713 1.02897529110147e-13 163.023095433736 23.023145789767 7.08083495289311 9.38106175690802e-12 -123.460059866181 56.233291779262 -2.19549764845372 0.0288569974512113 COQ10B other 1.38283989371127e-09 1 1.2982451365385e-07 7.08083495289311 -2.19549764845372 0.381056443901481 3.82998330875253 62.7093109507254 0.0610751936305278 0.951337812425269 -361.329382777106 261.802985783842 -1.38015760857456 0.168510653058084 GNLY other 1 1 1 0.0610751936305278 -1.38015760857456 3.92699210917959e-08 924.254255194273 189.670542450277 4.87294570497984 1.74504886515963e-06 -1048.69494658997 463.264188696484 -2.26370820835677 0.0242720267998616 SF3B1 essential 0.000442650550546724 1 0.0205200296054121 4.87294570497984 -2.26370820835677 0.149210290539732 37.059428770911 18.9468537976751 1.95596742164434 0.0513469939332878 9.09322848244922 77.5558624060435 0.117247467829597 0.906738202177009 ST3GAL5 other 1 1 1 1.95596742164434 0.117247467829597 0.0216896664174364 49.8443555525803 20.1804523942627 2.46993251582165 0.0140383957901923 -51.5353112702985 63.7121099051784 -0.808877799636483 0.419190194985711 CHST10 other 1 1 1 2.46993251582165 -0.808877799636483 0.03326365324762 22.727158098484 13.923749910427 1.63225842497102 0.103611750180156 -75.4639525084045 43.9680173631535 -1.71633739782057 0.0870710969337082 PDCL3 other 1 1 1 1.63225842497102 -1.71633739782057 7.20869789068762e-12 203.752875924405 34.0420135086182 5.98533561690826 5.87334536674289e-09 -243.951461439135 83.1465211515335 -2.93399480892937 0.00359198123778361 MOB4 other 9.30714984666679e-08 1 7.65061967471929e-05 5.98533561690826 -2.93399480892937 6.52007286500347e-07 384.08401807724 82.8323597389807 4.63688369240664 5.18995289881749e-06 -347.191674492311 202.315369780492 -1.71609144114462 0.087128486631821 HSPE1 essential 0.00683760041352914 1 0.0593990109269662 4.63688369240664 -1.71609144114462 0.0147026648685738 241.397560291898 83.6599720372186 2.88546068584035 0.00417636382422446 -81.8156926220979 345.16944883057 -0.237030516169054 0.812786219782843 KDM3A other 1 1 1 2.88546068584035 -0.237030516169054 0.000116464102454344 32.5145321235535 11.6482030759934 2.7913775121731 0.00556371759379236 -33.7084041169504 20.4368232826278 -1.64939548827063 0.100047896198647 PLCD4 other 0.996583324701821 1 1 2.7913775121731 -1.64939548827063 0.000108734915483018 315.438365268973 78.6083673497956 4.01278357385695 7.49279679773311e-05 -422.570129400381 324.327228074244 -1.30291290037371 0.193550139239632 CHMP3 essential 0.933054309759778 1 0.787043375633886 4.01278357385695 -1.30291290037371 2.86860317032312e-06 54.8529284077029 24.8573977560738 2.20670437613687 0.028046741924077 -136.438155565403 43.6364098112861 -3.12670442310575 0.00193054998728013 ZNF142 other 0.028648739862017 1 1 2.20670437613687 -3.12670442310575 0.415310647660826 -446.764447813523 401.916004326259 -1.11158660766059 0.267155626832917 -1168.00766096556 1293.72555134406 -0.90282491503094 0.367302175541882 IL1R2 other 1 1 1 -1.11158660766059 -0.90282491503094 0.0285275782989231 12.7189860122001 6.17722395964597 2.05901325503003 0.0403019104408621 26.8500514077737 10.8426087989233 2.47634604417711 0.0137902105370277 PRKAG3 other 1 1 1 2.05901325503003 2.47634604417711 0.0512594749376981 165.894669030029 69.8431518623626 2.37524602779885 0.0181336271984907 -113.02667346878 284.510000306406 -0.397267840663087 0.691438155169068 SMYD1 other 1 1 1 2.37524602779885 -0.397267840663087 0.400188424670721 66.2977874638752 90.5028687541799 0.732549016141693 0.464373125118698 -291.440474724025 291.319262027135 -1.00041608198526 0.317869822269228 IL1R1 other 1 1 1 0.732549016141693 -1.00041608198526 0.228989746643347 33.2135967050068 20.8897709478518 1.58994547082012 0.112837623266298 5.62838029100862 36.6875684186894 0.153413827451737 0.878168941408342 WNT6 other 1 1 1 1.58994547082012 0.153413827451737 0.000271925343915019 26.9804216610604 7.71741248729437 3.49604504171312 0.000539330979469257 -38.0330572795754 24.8415430527859 -1.5310263617183 0.126757038338235 IL1RL2 other 1 1 1 3.49604504171312 -1.5310263617183 0.537218596916849 8.1959605817975 14.4973194589351 0.565343172923329 0.572239010943021 48.7003667029894 46.6653539747993 1.04360864227643 0.297459183351962 IL1RL1 other 1 1 1 0.565343172923329 1.04360864227643 0.00297565229194684 -23.9844932960629 7.02423512348455 -3.41453451862311 0.000721719405885668 -22.7610840005686 22.6102776701661 -1.00666981328591 0.3148588402568 IL18R1 other 1 1 1 -3.41453451862311 -1.00666981328591 0.000600738236508866 -7.63037623762376 1.96018291902121 -3.89268581191079 0.00012074489612618 -3.01268646864686 6.31250372527475 -0.477256980710254 0.633505948352946 IL18RAP other 1 1 1 -3.89268581191079 -0.477256980710254 0.432375703902052 31.461916851793 27.9116612235623 1.12719614213552 0.260506711524047 71.5110358011814 89.4995458794784 0.799010040760199 0.42487908601354 SLC9A2 other 1 1 1 1.12719614213552 0.799010040760199 0.000842996855910194 436.404406116227 125.362712006239 3.48113405599033 0.000568632528353528 -405.2867019622 397.941736469891 -1.01845738915819 0.309230015205911 FHL2 other 1 1 1 3.48113405599033 -1.01845738915819 0.691005059464748 17.7466524374283 51.2070201440036 0.346566786888232 0.729144577751401 -50.5794735464398 92.4333723194348 -0.54719926664198 0.584623246083025 MLPH other 1 1 1 0.346566786888232 -0.54719926664198 1.81475846205965e-25 155.306228223865 42.7525580682335 3.63267685587362 0.000326590924100072 -613.658466960238 75.0416797764402 -8.1775683698501 6.87180063124108e-15 CNPPD1 other 2.71034176308609e-21 1.05482139689551e-10 1 3.63267685587362 -8.1775683698501 0.0742251473018151 111.019498056233 49.0602393255713 2.26292206443369 0.0243103499987214 -3.31148373877932 154.51966060957 -0.0214308245676682 0.982915341431083 UXS1 essential 1 1 1 2.26292206443369 -0.0214308245676682 0.0232717372101141 98.5411500907119 77.4091632615429 1.27299076671027 0.203945358914472 -214.763633052868 135.872890505495 -1.58062165494435 0.114952460881701 ABCB6 other 1 1 1 1.27299076671027 -1.58062165494435 3.00786429945333e-13 50.6343957976634 24.4188869991521 2.07357508961901 0.0389184842622374 -250.46146415557 42.8613954693161 -5.84352099163156 1.25830294014311e-08 STK16 other 4.005572887582e-09 0.00019114879963714 1 2.07357508961901 -5.84352099163156 8.2069348746319e-23 3641.03544395593 464.587489962747 7.83713621786907 6.88842784586493e-14 -2775.98364571632 837.564855039116 -3.31435067865482 0.00102394062509277 HDLBP other 1.21208221163439e-18 1 9.82152042263422e-10 7.83713621786907 -3.31435067865482 4.82963625595222e-12 95.6552895186384 51.3277105468887 1.86361886200351 0.0632910118718586 -523.334900750151 92.5584726491936 -5.65410043804035 3.47251654619624e-08 PPP1R7 essential 6.26548711484682e-08 0.000526190432245116 1 1.86361886200351 -5.65410043804035 0.0333685854828551 -19.8193051721073 21.2698663388182 -0.931802055377115 0.352141302404396 -99.9836634293854 38.3556235179253 -2.6067536976073 0.00956834196786773 PASK other 1 1 1 -0.931802055377115 -2.6067536976073 1.57744208972603e-19 340.084296727977 59.2138197255705 5.74332644480824 2.170279907454e-08 -504.406435678394 107.195853347679 -4.70546592919412 3.78421136152026e-06 STK25 other 2.28145449437076e-15 0.0562485176776372 0.000277340069373547 5.74332644480824 -4.70546592919412 0.0246740781780159 7.91463290438318 3.10935263937721 2.54542788236732 0.0113922893736452 15.2727855074241 9.67702848502991 1.57825158115951 0.11551467739616 TPO other 1 1 1 2.54542788236732 1.57825158115951 0.00312665666263587 35.7195472736367 11.54554595781 3.09379455975178 0.00215208025894555 -31.426728989495 32.4709571340924 -0.967841165251606 0.333861521340337 PROC other 1 1 1 3.09379455975178 -0.967841165251606 0.0050746007803477 -160.513656266534 53.2880883346741 -3.0121864244488 0.00280117810738755 -321.190384495206 160.39884097319 -2.0024482879455 0.0460825991677326 ID2 other 1 1 1 -3.0121864244488 -2.0024482879455 9.35498330639802e-05 37.2214801980572 12.0472338441242 3.08962876288909 0.00218044570412199 -80.8242465670166 36.2652848221757 -2.22869465835806 0.0265306719397522 TAF1B essential 0.808644757005045 1 1 3.08962876288909 -2.22869465835806 0.000857859772387082 90.6702724822645 27.0888546705133 3.34714308098676 0.000914109328108689 -74.4050529153611 81.544447700069 -0.912447812376294 0.36222207706946 HPCAL1 other 1 1 1 3.34714308098676 -0.912447812376294 0.00190453272292842 4156.24317420568 1176.98359347779 3.53126687341891 0.000474527146165383 5003.27164134616 3543.02454827156 1.41214704362886 0.158881423553705 ODC1 other 1 1 1 3.53126687341891 1.41214704362886 8.17495919694865e-07 455.89022096047 87.7476878305438 5.19546705140396 3.65618936666494e-07 -215.163945361195 305.055201091987 -0.705327903248284 0.481122518923516 BIRC6 other 0.00851422000362202 1 0.00444702312667456 5.19546705140396 -0.705327903248284 1.74320898258479e-13 190.790124047829 26.525595803996 7.19268006108603 4.55412838326464e-12 -134.077333192348 79.8488930617874 -1.67913828296403 0.0941042515000231 NOL10 essential 2.33241361869845e-09 1 6.33342634260614e-08 7.19268006108603 -1.67913828296403 5.06579793212504e-05 386.454014346636 90.142675082977 4.28713718547738 2.40063128747832e-05 -204.745331356591 244.924115117075 -0.835954153631308 0.403806408286743 PLEKHB2 other 0.451818517566233 1 0.262388999721381 4.28713718547738 -0.835954153631308 1.0463390407119e-16 527.792845732224 61.5390007904893 8.57655858809122 4.35745180408013e-16 -351.58392639433 190.353317266394 -1.84700708894029 0.0656749512055031 GORASP2 other 1.46979245048801e-12 1 6.32702001952434e-12 8.57655858809122 -1.84700708894029 2.32890934730619e-10 307.536309507777 46.8745740565168 6.56083421978362 2.15252619308696e-10 -159.842132431479 160.630297107814 -0.995093300015463 0.320442741965758 STRN other 2.88412133570399e-06 1 2.90612561328671e-06 6.56083421978362 -0.995093300015463 1.90510731968308e-12 324.831301443424 45.5796164756879 7.12667912896303 6.89483035154327e-12 -248.861115863534 156.158157896056 -1.59364787095647 0.112005231413571 CEBPZ essential 2.49283292780531e-08 1 9.56312969759051e-08 7.12667912896303 -1.59364787095647 0.00918159862903814 111.665051088832 36.2842618703966 3.07750648167207 0.00226840475360689 37.068327794157 124.311785232364 0.298188363435283 0.765753528705546 PRKD3 other 1 1 1 3.07750648167207 0.298188363435283 1.57001333085948e-09 82.5874263519182 13.6818927077752 6.03625741817032 4.40431342847825e-09 -74.8368423878832 42.2012750679365 -1.77333130971539 0.0771339114266258 DCAF17 other 1.88213198103435e-05 1 5.75555678833538e-05 6.03625741817032 -1.77333130971539 0.23510908813978 11.0864205810775 17.2261717284222 0.643580056895959 0.52030874025528 98.2966649423412 59.0308315000463 1.66517500168135 0.0968565349158473 QPCT other 1 1 1 0.643580056895959 1.66517500168135 1.71473236849893e-07 215.51647361338 56.7551418349764 3.79730305740447 0.000175482548828734 -542.859387659465 146.681216007392 -3.70094687265278 0.000253456993908116 RAB3GAP1 other 0.00186717207605849 1 1 3.79730305740447 -3.70094687265278 7.9686342593224e-06 77.1532644847436 19.2024625898385 4.01788385858236 7.34523309217346e-05 -165.950357374973 70.6832027069094 -2.34780472615386 0.0195008452531458 SLC25A12 other 0.076745916551534 1 0.772351259642039 4.01788385858236 -2.34780472615386 0.271983205403446 -4.50891982159251 4.17917681685452 -1.07890142465572 0.281446776675613 -19.6031803552902 14.3138998289799 -1.36952057716666 0.171799917048697 RMDN2 other 1 1 1 -1.07890142465572 -1.36952057716666 0.00408514962606642 17.0678152942371 6.36400199553008 2.68193116630465 0.00770703591677352 -38.7389137460263 23.5575632314337 -1.64443636913752 0.101086841792365 DLX2 other 1 1 1 2.68193116630465 -1.64443636913752 1.15703753092525e-11 508.034598942983 76.6850440614613 6.62495021240133 1.50927563581289e-10 -415.806938822385 197.712088103773 -2.10309315333386 0.036253110746085 DARS essential 1.48552048595493e-07 1 2.04386106601782e-06 6.62495021240133 -2.10309315333386 0.776753622617266 27.4307566187427 76.042893051197 0.360727419987487 0.718541977891015 -141.423350962691 260.450897758355 -0.542994292513067 0.587512922703684 SRSF7 essential 1 1 1 0.360727419987487 -0.542994292513067 1.39050753710297e-07 8541.8956532054 1553.16527237402 5.49966948472206 7.82848528476258e-08 -3187.53470883291 5037.09390211166 -0.632812246660049 0.52731103421418 SDC1 other 0.00152232765162033 1 0.000979030369712408 5.49966948472206 -0.632812246660049 0.856817708872323 -4.8012703001968 8.71472278346048 -0.550937811734992 0.582069333624101 -4.49816272965876 21.1411657359165 -0.212767961135506 0.831646458203309 PLCL1 other 1 1 1 -0.550937811734992 -0.212767961135506 0.00453051206305351 419.0886505822 134.328036525732 3.11988964792111 0.00197440226533579 -664.161250343239 571.558694824425 -1.16201757817237 0.246096978241902 SLC1A4 other 1 1 1 3.11988964792111 -1.16201757817237 0.000657550589538485 151.490278073932 45.3828398234281 3.338051974344 0.000943492586365093 -212.991228777652 155.438607088206 -1.37025950481393 0.171569442146102 SOS1 other 1 1 1 3.338051974344 -1.37025950481393 0.115342493312573 -64.538075115572 105.633699335932 -0.610961042936979 0.541665973067176 508.430017226904 271.781423337649 1.87073130673561 0.0623093819016256 KYNU other 1 1 1 -0.610961042936979 1.87073130673561 0.448328356865186 61.5355614519076 48.962133489245 1.25679902133808 0.209769528595501 -2.40852998858192 183.336113579907 -0.0131372370754012 0.989526726237553 WIPF1 other 1 1 1 1.25679902133808 -0.0131372370754012 1.62970780836298e-13 131.878755772411 19.0475079583666 6.9236750582106 2.46441936714305e-11 -94.4733244912707 47.0248617703194 -2.00900802117613 0.0453864687071144 ORC2 other 2.18234172617887e-09 1 3.38463355883427e-07 6.9236750582106 -2.00900802117613 4.6846890665459e-05 226.213733312212 52.8403342868493 4.2810806624384 2.46324783790463e-05 -158.243885344509 187.555557961684 -0.843717387339899 0.399459581421824 COX7A2L other 0.419513905909185 1 0.268962031420806 4.2810806624384 -0.843717387339899 4.23098397044255e-08 155.513146717365 25.9849902111137 5.98472985573234 5.82449223080551e-09 -11.2049472108735 112.056501204684 -0.099993727185952 0.920412117050101 PNO1 essential 0.000476028006514492 1 7.58873092751649e-05 5.98472985573234 -0.099993727185952 0.000118618481948522 69.9460355406935 20.3612790293308 3.43524763056069 0.000670832454549325 -108.214246181094 53.5915088430454 -2.01924238591645 0.0443033678261744 ORC4 essential 1 1 1 3.43524763056069 -2.01924238591645 0.155195775914751 -103.98044319503 55.8712992514486 -1.86107079284243 0.0636539567625778 -129.701557718893 240.821734066186 -0.538579120451173 0.590552914633341 PLEK other 1 1 1 -1.86107079284243 -0.538579120451173 0.303731461794676 139.050087721486 191.560378604542 0.725881253390823 0.468447138223772 -609.949686237823 500.726113694835 -1.21813037018787 0.224080287383221 RND3 other 1 1 1 0.725881253390823 -1.21813037018787 4.16021641471082e-22 247.262909469115 24.238754104577 10.2011393985974 2.93405256233331e-21 -195.537288595459 91.1441322059949 -2.14536343550372 0.0327003820414186 ATF2 other 6.11759823783227e-18 1 4.37819323351377e-17 10.2011393985974 -2.14536343550372 5.53227083858822e-13 195.03716905008 25.592670131462 7.62082143239573 2.92282153487071e-13 -69.4954593096714 91.1421722081938 -0.762495095584563 0.446329773287459 THADA other 7.3274927257101e-09 1 4.13082367523278e-09 7.62082143239573 -0.762495095584563 0.000192920423706702 166.015818239963 40.4770121889276 4.10148400937005 5.21568690334736e-05 -149.879403000262 174.014579905876 -0.861303708467023 0.389717729452589 AAK1 other 1 1 0.55557496894456 4.10148400937005 -0.861303708467023 0.00079397356521952 34.2846213904009 29.6667665972265 1.15565750241235 0.248691561554619 -225.108739733661 72.478788993667 -3.10585680113019 0.00206870995457167 TRAK2 other 1 1 1 1.15565750241235 -3.10585680113019 0.00359956808576472 20.6121241044563 6.1531064917012 3.34987280526612 0.000905454340354714 -12.5802831984078 26.440371336668 -0.475798279767773 0.634543762230754 C2orf42 other 1 1 1 3.34987280526612 -0.475798279767773 0.444401213395232 55.7482962117992 48.6465312681606 1.14598707777314 0.252659428808185 117.431152988832 209.037882361659 0.56176972165104 0.574667394328614 TIA1 other 1 1 1 1.14598707777314 0.56176972165104 2.91432655174715e-06 407.998774839903 83.0728359819265 4.91133798452082 1.44540500805069e-06 557.727597382849 357.195731442613 1.56140610955888 0.119416349460569 PCYOX1 other 0.0290937219660918 1 0.0170890234101833 4.91133798452082 1.56140610955888 0.604364925134575 257.116812058253 281.704403495637 0.912718469671473 0.362077741917969 -285.229307851139 1025.48086086406 -0.278142009994031 0.781082978299462 EPAS1 other 1 1 1 0.912718469671473 -0.278142009994031 3.15455612355758e-06 107.88952976737 24.6369400682929 4.37917734378959 1.61891781112258e-05 -2.917433366297 40.4285015725868 -0.0721627874597069 0.942517724055338 ARID3A other 0.03141622443451 1 0.179052309910158 4.37917734378959 -0.0721627874597069 1.36476197936287e-14 338.99232434241 62.2475499525118 5.44587416855803 1.03320864429782e-07 -578.781330513889 136.789749872966 -4.23117471193122 3.0445518614825e-05 SUMO1 other 1.86330953042413e-10 0.442434276510637 0.00128572483696421 5.44587416855803 -4.23117471193122 0.289072446803245 -31.3883445951214 22.8310455161469 -1.37480977701711 0.170152300764573 -81.4550266447565 94.794232956136 -0.859282512285828 0.39082790574912 CD207 other 1 1 1 -1.37480977701711 -0.859282512285828 0.0021379377656822 28.1728267523721 7.9934446152315 3.52449139369638 0.000486562030803061 19.7692602010785 13.1170099574652 1.50714684712328 0.132765768806535 GRIN3B other 1 1 1 3.52449139369638 1.50714684712328 0.547656113877683 3.67907957879772 3.3547384869836 1.09668148294496 0.273605257223712 0.0912048917839388 13.928834814732 0.0065479196930008 0.994779633419806 VAX2 other 1 1 1 1.09668148294496 0.0065479196930008 0.180921830783297 -55.2033872672679 71.9358088405329 -0.767397880930797 0.443410826708954 488.970343092165 298.676633809644 1.63712285375427 0.102587791456019 ATP6V1B1 other 1 1 1 -0.767397880930797 1.63712285375427 3.33736210959129e-10 1867.09994260746 284.330224174356 6.56666011511502 2.18606794893053e-10 -1079.72640306554 1058.40243275623 -1.02014731792875 0.308459222877988 NFE2L2 other 4.10996143796167e-06 1 2.95053591067154e-06 6.56666011511502 -1.02014731792875 0.000184012166224186 343.382799068523 95.5851039194069 3.59243004389102 0.000379114548659709 -564.445171149703 347.955848175345 -1.62217469288018 0.105750727947125 MSH6 ts 1 1 1 3.59243004389102 -1.62217469288018 4.24229626782553e-14 72.4686733306516 9.01097692919011 8.04226599403412 1.83529373039951e-14 -30.7951037623643 34.0652545824954 -0.904003335357093 0.366688871266367 PLEKHA3 other 5.73516032447333e-10 1 2.6308935625277e-10 8.04226599403412 -0.904003335357093 0.000118060424364569 128.19060315166 29.920652701669 4.28435182981519 2.42717503193063e-05 -29.3123898254491 123.755421635049 -0.236857419563326 0.81291895678695 SPR other 1 1 0.265193143988741 4.28435182981519 -0.236857419563326 0.0405835092487664 -10.2281500307552 52.6319229861084 -0.194333580277027 0.846038004465002 -216.071571168122 92.3824933338078 -2.33888005584982 0.0199567713131551 EPHA4 other 1 1 1 -0.194333580277027 -2.33888005584982 0.133479456431709 -22.1543990709649 24.0953042097206 -0.919448821983634 0.358564398927664 -104.28792354171 52.0291178335091 -2.00441460251981 0.0458813112623847 PARD3B other 1 1 1 -0.919448821983634 -2.00441460251981 7.13341474423814e-12 164.870209886111 47.5699587625423 3.46584723163421 0.000600709740825567 -350.323671767338 83.0189727219062 -4.21980253767821 3.18849703068683e-05 FARSB essential 9.21066511776028e-08 0.462969768855728 1 3.46584723163421 -4.21980253767821 0.319961832425742 46.2519053802291 32.1858021002891 1.43702820380585 0.151690059894967 -50.6692306968518 133.485226121563 -0.379586806488294 0.704504724628025 ALMS1 other 1 1 1 1.43702820380585 -0.379586806488294 2.68400539216282e-10 169.209029766265 24.641744618726 6.86676338807921 3.61238895156684e-11 -65.6516947459548 100.358277708049 -0.654173190745074 0.51348680046318 BCL9 og 3.31662546309559e-06 1 4.95005658033204e-07 6.86676338807921 -0.654173190745074 0.149191321796871 137.629311114879 167.322055095403 0.822541362143835 0.411381350175558 -970.269564654644 539.509467289979 -1.7984291722042 0.0730513432158872 PRRX1 other 1 1 1 0.822541362143835 -1.7984291722042 0.00835887411437881 376.936099895943 644.964370207251 0.584429337972296 0.559345870705428 -4382.78492928432 1545.29928135389 -2.83620459943813 0.0048580289987273 DHCR24 other 1 1 1 0.584429337972296 -2.83620459943813 2.72955125449302e-06 63.9598344963704 21.9438644491126 2.91470240552625 0.00381207017613073 -135.360305027196 44.3791232542234 -3.05008966156885 0.00247951617998506 DNAJC16 other 0.0273037011986937 1 1 2.91470240552625 -3.05008966156885 0.0419801438628169 68.9543645929583 28.1291840591943 2.45134606278848 0.0147683750529576 -66.3411179327757 91.5787345322211 -0.724416189758925 0.469341227153826 MARK1 other 1 1 1 2.45134606278848 -0.724416189758925 0.00215958878348651 8.84331036665668 7.13298995455267 1.23977608590524 0.215972323804766 -44.6058586692139 15.8164260013754 -2.82022365010495 0.00510035875588403 MORN1 other 1 1 1 1.23977608590524 -2.82022365010495 0.160768186422597 10.8927692738253 22.675700177441 0.480371904222919 0.631293251722541 105.174322097176 54.8674654188653 1.91687954408431 0.0561491781753235 GPX7 other 1 1 1 0.480371904222919 1.91687954408431 0.00153254212483924 189.79046348783 53.4793935638718 3.54885219970115 0.000445066471795923 113.857840708808 169.006746393482 0.673688140494252 0.500997428948469 CACYBP other 1 1 1 3.54885219970115 0.673688140494252 0.00120802202033806 108.328149287921 62.0986072338181 1.74445376657219 0.0820461417348963 -418.96507953278 150.257463200668 -2.78831460752971 0.00561733704828161 SCP2 other 1 1 1 1.74445376657219 -2.78831460752971 0.868322355925718 2.319237887344 9.04756124866694 0.256338456695798 0.797854220612229 13.0560385327196 28.5935766234521 0.456607394893412 0.648263033754983 PAPPA2 other 1 1 1 0.256338456695798 0.456607394893412 0.327450184177366 56.8335865290636 38.3882746003441 1.48049338296007 0.139725500025242 -32.6148290095093 120.588182238969 -0.270464554684776 0.786977238320461 RALGPS2 other 1 1 1 1.48049338296007 -0.270464554684776 0.185597786987524 18.6544137282851 12.0277357959652 1.55094974189098 0.121902136217708 -38.2892280069146 37.1917763769469 -1.02950791107273 0.3040185736879 ANGPTL1 other 1 1 1 1.55094974189098 -1.02950791107273 1.31522127939751e-16 200.699720788606 26.3586042991397 7.61420136327766 3.01086496601938e-13 -145.92005725655 58.3894063223477 -2.49908444780164 0.0129522697821966 CEP104 other 1.8459130656344e-12 1 4.25375002399218e-09 7.61420136327766 -2.49908444780164 0.000362683111819652 276.213056895928 70.7938203041367 3.90165491435964 0.000116483296740354 195.316615745335 222.382959200556 0.878289489659994 0.380445612490808 FAM20B other 1 1 1 3.90165491435964 0.878289489659994 9.85842568386374e-05 216.57483561215 147.593122065873 1.46737756191301 0.143261679416898 -1302.94186486237 355.426635068099 -3.66585319249563 0.000288799484331935 TMEM59 other 0.850584968003763 1 1 1.46737756191301 -3.66585319249563 5.23630568748988e-09 103.348135418341 30.4961867614657 3.38888714929203 0.000790092896563165 -330.614512255021 73.7903773399957 -4.48045563897424 1.04033264062391e-05 LRRC42 other 6.1578954884881e-05 0.153095351394214 1 3.38888714929203 -4.48045563897424 8.19421793083064e-06 33.0145937088448 27.9599276760902 1.18078251457986 0.238566025683284 -260.14464984122 61.4088718530566 -4.23627143751659 2.97504664292148e-05 WRAP73 other 0.0788283764945907 0.432452780015066 1 1.18078251457986 -4.23627143751659 1.8187220659815e-07 164.000915099135 71.3408521180013 2.29883594364516 0.0221603243619531 -775.557453784548 170.950973528153 -4.53672440570702 8.10020602556998e-06 MRPL37 other 0.00197749650234168 0.119486139083183 1 2.29883594364516 -4.53672440570702 1.32028845771856e-14 531.450196454281 95.2036645642873 5.58224516762602 5.08098765958966e-08 -868.573072981229 207.19587950454 -4.19203835065744 3.58462566434242e-05 ICMT other 1.80311794670624e-10 0.519770721329651 0.000640052015478509 5.58224516762602 -4.19203835065744 2.1816160051528e-07 515.825036387788 148.101936244598 3.48290541952049 0.000565246301076075 -1012.06873286422 322.320690878487 -3.13994342127346 0.00184791636800739 RPL22 other 0.002362908295181 1 1 3.48290541952049 -3.13994342127346 0.0106474615562368 600.257457730166 213.661295701117 2.80938789480078 0.00526891136919542 -834.694699307616 671.169192459343 -1.24364274863253 0.214541366747629 QSOX1 other 1 1 1 2.80938789480078 -1.24364274863253 1.50820807045468e-08 90.273075296747 28.5563504060008 3.16122592744825 0.00172140979670812 -189.580521226033 54.5604176899108 -3.47468969727279 0.000581954604651382 STXBP3 other 0.00017354950266722 1 1 3.16122592744825 -3.47468969727279 2.77075511957129e-10 186.6386370591 29.6411580686221 6.29660408770175 1.00647846371201e-09 -46.5118842099038 65.4282478026516 -0.710883842559801 0.477675651649561 PHF13 other 3.42160549715859e-06 1 1.33952218735431e-05 6.29660408770175 -0.710883842559801 0.022786728388551 139.946936664082 149.288070193655 0.937428801126195 0.349244992376172 -740.51215345611 335.863992965714 -2.20479768288738 0.0281794248737151 ERRFI1 other 1 1 1 0.937428801126195 -2.20479768288738 3.95041073957136e-07 289.412975032046 118.256728022642 2.44732777467541 0.0149292248847432 -1073.02679552191 266.050574685725 -4.03316849358223 6.88627550656807e-05 PARK7 other 0.00420718743764349 0.988731437233043 1 2.44732777467541 -4.03316849358223 0.608297792340838 -116.497063614437 130.217754778244 -0.8946327158906 0.371657960165995 5.98450361791681 248.562265314844 0.0240764768149199 0.980806660154642 KIAA1324 other 1 1 1 -0.8946327158906 0.0240764768149199 2.88827461008122e-05 153.038832299992 41.21076545947 3.71356441924145 0.00024103371096212 -71.0159225828752 76.54967101151 -0.92771035648471 0.354257028676945 AMPD2 other 0.264479306045138 1 1 3.71356441924145 -0.92771035648471 5.2013755541733e-05 263.225358324146 78.5390650970144 3.35152141165674 0.000900264215802106 -346.860237369478 159.252300965476 -2.17805479271959 0.0301340508772112 SRSF4 other 0.463390548121299 1 1 3.35152141165674 -2.17805479271959 2.39304734867809e-07 55.4524366041899 16.3747713216216 3.38645563440445 0.000796590674039027 -120.912359210498 33.2028399819959 -3.64162701973873 0.000316028084022237 MECR other 0.00258568766024668 1 1 3.38645563440445 -3.64162701973873 0.000875265521804856 -13.1770192808754 31.40117519721 -0.419634590047005 0.67503399949527 -208.383289907938 58.2610906693279 -3.57671453647611 0.000401700181563994 KCNC4 other 1 1 1 -0.419634590047005 -3.57671453647611 0.000665152787641645 162.588014460105 42.1031089627338 3.86166291434713 0.000136370057644681 -52.9793374235525 140.822848206024 -0.376212653688439 0.707008893522728 EDEM3 other 1 1 1 3.86166291434713 -0.376212653688439 7.00897407053761e-11 60.717643442885 44.1116729388137 1.37645297486461 0.169643790815078 -451.938896881063 80.8388573298903 -5.59061461045612 4.85197731423839e-08 WDR77 essential 8.81518668851515e-07 0.000734686404921977 1 1.37645297486461 -5.59061461045612 9.6628132147509e-15 140.553204386635 94.8598959409687 1.48169258454702 0.139406131087605 -1175.27418675501 173.839827043894 -6.76067277988174 6.52157570747357e-11 ATP5F1 essential 1.32390203855302e-10 9.97801083243456e-07 1 1.48169258454702 -6.76067277988174 7.67315503345869e-13 114.142516552333 40.294309276539 2.83272051566825 0.0049080817066352 -384.981876030742 73.8431735139767 -5.21350664808406 3.3315280990445e-07 RAP1A other 1.01347031681922e-08 0.00501828077559072 1 2.83272051566825 -5.21350664808406 0.0156952981454323 192.602488377411 150.332648526961 1.28117538182578 0.20106849856424 -760.297293845982 337.711847217226 -2.25131957943109 0.0250499016038263 HDAC1 other 1 1 1 1.28117538182578 -2.25131957943109 4.82120632144731e-12 544.915234993713 168.894320929454 3.22636801518815 0.00138425212818854 -1419.70540524902 310.459071173344 -4.5729229295295 6.89866271564868e-06 CAPZA1 other 6.25503308144574e-08 0.101996728250866 1 3.22636801518815 -4.5729229295295 0.0130763912981531 23.1263290270949 17.8131646536088 1.29827178251618 0.195137691342504 -92.2988566698047 40.0299389858226 -2.30574562460598 0.0217699822774781 S100PBP other 1 1 1 1.29827178251618 -2.30574562460598 0.195647376874843 57.4343203279413 93.1249335795472 0.616744819247371 0.537844340189647 -326.613438604979 214.493597182608 -1.52271882655275 0.128822841710074 RNF19B other 1 1 1 0.616744819247371 -1.52271882655275 1.78082312481453e-07 271.094359954049 47.5516902506413 5.70104571520237 2.71968091957501e-08 -84.7002918556211 164.424735641998 -0.51513108125069 0.60681931327252 SCAMP3 other 0.00193753555979821 1 0.000346351365107877 5.70104571520237 -0.51513108125069 0.00054094413093734 47.3495260819701 13.7592325667498 3.44129120953982 0.00065655643603528 -34.0105659332691 32.4426771249196 -1.04832797251325 0.295286132425128 TRIM62 other 1 1 1 3.44129120953982 -1.04832797251325 0.372269701035092 8.58343528387186 8.28974361594922 1.03542831739182 0.30125566596205 -14.3469394102766 19.6772891825412 -0.72911158021736 0.466470059679343 DLGAP3 other 1 1 1 1.03542831739182 -0.72911158021736 0.00983966428646132 369.457722494091 185.552498815549 1.99112232307556 0.0473228025468916 -829.908591838428 440.444282343297 -1.88425329856267 0.0604427151444027 SFPQ other 1 1 1 1.99112232307556 -1.88425329856267 0.357843256067016 12.3611087431434 16.8503901929474 0.733579970647624 0.463741866418231 -71.3977601688278 56.7045534839474 -1.25911863831253 0.208905176656003 RHOU other 1 1 1 0.733579970647624 -1.25911863831253 4.23866230715617e-09 239.913205084655 37.5002188743521 6.39764812809509 5.59862449268856e-10 10.254168380026 130.578530585396 0.0785287469085126 0.937456545683215 GON4L other 5.00670791721287e-05 1 7.49543847081144e-06 6.39764812809509 0.0785287469085126 0.000557138182353098 194.066954213076 53.5585610127308 3.62345347865016 0.000337985522380113 -292.006488119715 186.494863423154 -1.56576155911145 0.118392776311798 ARHGEF2 other 1 1 1 3.62345347865016 -1.56576155911145 0.000967346220893709 170.732625641393 46.5656401267787 3.66649368883493 0.000287829264277805 126.93617542417 162.144996643787 0.782855950239604 0.434290665197626 LAMTOR2 essential 1 1 1 3.66649368883493 0.782855950239604 3.67043650125533e-10 267.22662291059 42.8259982446022 6.23982239443236 1.38770543166321e-09 -417.766398882563 143.562961883452 -2.90998732125432 0.00386771260970199 MEF2D other 4.51280167829342e-06 1 1.83968109075592e-05 6.23982239443236 -2.90998732125432 0.472440372010784 32.1877631524168 36.3403040428336 0.885731806604526 0.37642716469592 -50.2431066274815 85.0460033522456 -0.590775634915887 0.555087777749713 DOCK7 other 1 1 1 0.885731806604526 -0.590775634915887 1.52109072796571e-07 395.288016978064 96.4230651086159 4.09951723203147 5.25415984363724e-05 -515.011381958762 203.04082542292 -2.53649176655005 0.0116719032716777 SRM other 0.00166163951122974 1 0.55951548174893 4.09951723203147 -2.53649176655005 0.000104643418669582 264.425180430854 78.3945074573579 3.3730064644476 0.000834813873049559 -254.601530244366 165.077572309438 -1.5423144808982 0.123985480982734 FBXO2 other 0.899410183465057 1 1 3.3730064644476 -1.5423144808982 0.0300626228003264 39.4120080297447 34.3272704999995 1.14812530841173 0.251774396178127 -138.876313842487 72.283922202479 -1.92126145913156 0.0555868610296991 FBXO6 other 1 1 1 1.14812530841173 -1.92126145913156 0.0016143029735461 168.812802934836 46.6250527469516 3.62064583285374 0.000341684433455399 -2.89061114868385 155.947455837368 -0.0185358019030356 0.985223004569694 C1orf21 other 1 1 1 3.62064583285374 -0.0185358019030356 0.00063150281048551 15.9227771679473 4.379698590872 3.63558743543058 0.000323221398935683 -21.9856950404152 14.9905710952587 -1.46663492009113 0.143460496361192 SWT1 other 1 1 1 3.63558743543058 -1.46663492009113 6.99142450086845e-05 114.391668020851 53.5993761960066 2.13419774891659 0.0335864049004476 -341.975976610075 112.865750251061 -3.02993579406842 0.00264542220829649 MAD2L2 essential 0.613427585706198 1 1 2.13419774891659 -3.02993579406842 0.313633189402367 11.3911940757039 7.59267124143008 1.50028806904569 0.13452885822738 11.8029387045889 17.6747137280628 0.667786697209633 0.504752587737957 DNAJC6 other 1 1 1 1.50028806904569 0.667786697209633 0.652736454963251 19.8802564835293 22.6844152151209 0.876383909172919 0.381480824632779 -2.57508528893276 52.8062564895484 -0.0487647763753606 0.961137269986602 LEPR other 1 1 1 0.876383909172919 -0.0487647763753606 0.0033406675491735 786.884104722995 250.27635533574 3.14406090686197 0.00182288974597084 -1203.68811279394 857.295464860858 -1.40405281741377 0.161275927354778 IVNS1ABP other 1 1 1 3.14406090686197 -1.40405281741377 2.29091141632162e-09 769.348283851279 165.897543706772 4.63749050565282 5.14606878087832e-06 -1007.91174968059 349.335236044556 -2.8852278432973 0.0041768194650577 MFN2 essential 2.73374459309659e-05 1 0.058912195403495 4.63749050565282 -2.8852278432973 0.00725279622979359 49.4928827877509 15.9085791205189 3.11108128594055 0.00203408184086368 -35.3097162970784 51.5460141780788 -0.685013513849821 0.493837544114141 PRG4 other 1 1 1 3.11108128594055 -0.685013513849821 0.00260632034562051 60.381430388283 44.5954135343125 1.353982968267 0.17669723932656 -246.259471099438 93.9058467378483 -2.62240829143372 0.00914869398537931 MIIP other 1 1 1 1.353982968267 -2.62240829143372 9.04746695685315e-05 377.253805095989 86.9678405898285 4.3378541140886 1.93278827147288e-05 140.264491218154 298.578497535074 0.469774254931661 0.638837273463915 SMG7 essential 0.783148739785208 1 0.212645365627446 4.3378541140886 0.469774254931661 0.265389089380155 18.1062315400331 46.3388635027047 0.390735339009259 0.696253689529983 -253.852270408563 159.090856439393 -1.59564337065009 0.11155861566845 NCF2 other 1 1 1 0.390735339009259 -1.59564337065009 0.0304293810966038 25.9216883076342 29.3933167176619 0.881890552081123 0.378497937907316 -144.522834609277 66.4189755918777 -2.17592688416818 0.030292001158217 SLC35D1 other 1 1 1 0.881890552081123 -2.17592688416818 0.0118197899601361 185.897437328392 61.969476051547 2.99982264129134 0.00291548203318842 -25.2193829943975 201.272211873953 -0.12529987502791 0.900365575507348 PLA2G4A other 1 1 1 2.99982264129134 -0.12529987502791 0.35944088019588 88.9091850034504 67.0841715777046 1.32533774976211 0.18600461273462 -22.6411868435179 149.568397568381 -0.151376809617597 0.879773866865011 GADD45A other 1 1 1 1.32533774976211 -0.151376809617597 1.45686105529819e-06 402.021538646896 84.1834183364719 4.77554305338445 2.73274977457855e-06 -161.090449643017 187.692248205379 -0.858269061100207 0.391386302381772 WLS other 0.0148999036161784 1 0.0318010091267706 4.77554305338445 -0.858269061100207 2.3705678776294e-05 153.658376296987 49.334920095828 3.11459663861867 0.00200855914740284 -241.710163352921 105.062555042864 -2.30063092653998 0.0220552468936756 PRDM2 other 0.218566358317431 1 1 3.11459663861867 -2.30063092653998 0.419794285904661 64.476159509277 52.8004259873238 1.22112953264347 0.222947281333306 -89.3879498952454 180.71127255933 -0.49464512439808 0.621194359729071 RGS2 other 1 1 1 1.22112953264347 -0.49464512439808 0.0148661311899033 11.2734416301541 6.64582662044692 1.6963189493192 0.0907979940761299 -26.6325277170719 14.7371480193198 -1.80716972389486 0.0716748912088247 RPE65 other 1 1 1 1.6963189493192 -1.80716972389486 4.53848055203526e-05 132.316245994956 29.4933247805764 4.48631163083033 1.01693664318767e-05 -71.4815261469423 100.634307150099 -0.710309716152026 0.478037625127328 TROVE2 other 0.407010935906522 1 0.114049444533498 4.48631163083033 -0.710309716152026 0.0947001652250581 45.4348097472084 51.5646939203412 0.881122455946264 0.378914924513475 204.180876585325 93.9514478848657 2.1732594992633 0.0304962157500876 AMPD1 other 1 1 1 0.881122455946264 2.1732594992633 2.66770600502935e-07 157.957875347082 28.5235153819284 5.5378123359633 6.45052257112761e-08 -100.380040369332 97.6227116760648 -1.028244745981 0.304621121932425 UCHL5 other 0.00287578707342163 1 0.000809024540870825 5.5378123359633 -1.028244745981 3.72822075521506e-10 38.9814808825041 30.0778124797258 1.29602114212195 0.195905090419264 -290.261791571496 54.8021100647895 -5.29654407883813 2.20341711266154e-07 BCAS2 essential 4.58235613023483e-06 0.0033234140310274 1 1.29602114212195 -5.29654407883813 0.0743920812177127 135.260663744076 96.2517666260413 1.40527980405381 0.160911198858064 -277.056809860678 208.799398000416 -1.32690425601766 0.185489356319755 SRSF11 essential 1 1 1 1.40527980405381 -1.32690425601766 0.0278195345336863 8.83802528395253 4.90921181170678 1.80029414556465 0.0727587925908538 -14.903301300972 10.6495756584231 -1.3994267733273 0.162656686799418 CTH other 1 1 1 1.80029414556465 -1.3994267733273 0.0541514970155382 4.96418063640248 6.1698527582247 0.804586564855214 0.42165752276553 -23.5840525217085 12.4778685473851 -1.8900706023747 0.0596548838023913 AGMAT other 1 1 1 0.804586564855214 -1.8900706023747 0.413326864032021 94.0765931705686 73.0591567716911 1.28767696381381 0.198791808263978 41.1019738585215 133.114599119923 0.308771345369057 0.757697020508924 OLFML3 other 1 1 1 1.28767696381381 0.308771345369057 0.0893902716286569 3.86013064070888 1.96033689214643 1.96911594949494 0.0498159906468183 -6.63012210972772 6.72906837084492 -0.985295696868544 0.325235035205969 CFHR3 other 1 1 1 1.96911594949494 -0.985295696868544 8.11306935870301e-20 701.937744528214 88.2578400803962 7.95326221317904 3.16012858716601e-14 -565.304081987568 178.484529118641 -3.16724415712133 0.00168724776659612 PLEKHM2 other 1.175989403544e-15 1 4.52182799537585e-10 7.95326221317904 -3.16724415712133 0.000121080702196071 74.282259427971 33.8204566038123 2.19637068470559 0.0287824610448908 -205.378978176527 71.3276052491172 -2.87937576845914 0.00425309455017143 CRYZ other 1 1 1 2.19637068470559 -2.87937576845914 0.0314021253350194 -2.44931810971497 14.5843431249838 -0.167941613052093 0.866735633797769 -63.9863054188548 26.5728359632789 -2.40795922224025 0.0166091002644527 PHTF1 other 1 1 1 -0.167941613052093 -2.40795922224025 1.39231941939518e-13 77.9090701935018 21.7016710535932 3.59000327675699 0.000382522549722728 -245.958116415061 43.3788247482542 -5.67000415162145 3.19194609165115e-08 ZBTB17 essential 1.86584725393148e-09 0.000483867108033397 1 3.59000327675699 -5.67000415162145 0.000125544242106565 29.6555478944457 24.1511997283679 1.22791199725008 0.220385259014787 -139.105749450879 44.3876158930698 -3.13388648279706 0.00188530810712427 CD58 other 1 1 1 1.22791199725008 -3.13388648279706 0.00718170089270405 20.5787051901783 7.09460908237142 2.90061157017262 0.00398386901901809 -11.9847308365976 16.9345227331607 -0.70770998542105 0.479643728802544 TFAP2E other 1 1 1 2.90061157017262 -0.70770998542105 0.236640942431254 -67.7428305207584 39.8169356964442 -1.70135720732543 0.0898564854071788 -57.6113289850575 73.6276850347867 -0.782468292434265 0.434523514040815 CD2 other 1 1 1 -1.70135720732543 -0.782468292434265 3.27647984006882e-05 26.1216482037478 42.7231221308097 0.611417117966437 0.541361678970838 -302.756797460055 79.0016741602469 -3.83228331143899 0.000153090954641016 TTF2 essential 0.297995841454259 1 1 0.611417117966437 -3.83228331143899 0.597479973072072 -9.22701457563842 10.5686708749238 -0.873053450602885 0.383290646994286 -19.0246987127721 35.8460731745938 -0.530733132750955 0.595973007574335 NR5A2 other 1 1 1 -0.873053450602885 -0.530733132750955 0.665003812194499 -3.23590116303808 11.2388687109691 -0.287920541315678 0.773593946397252 -32.3524296483653 37.4959899402764 -0.862823723280707 0.388880571363004 KIF21B other 1 1 1 -0.287920541315678 -0.862823723280707 9.20258810429372e-07 369.635803803489 72.6195693104216 5.09003023996787 6.11919964893763e-07 -401.901669409868 242.279068325906 -1.65883776996056 0.0981282534714991 TMEM9 other 0.00955780800511946 1 0.00736751637732091 5.09003023996787 -1.65883776996056 2.19524168451302e-08 139.396560711034 35.3100880773842 3.94778286606191 9.71493739799077e-05 -321.916424875451 83.8689864413107 -3.83832497010942 0.000149451439760085 ADPRHL2 other 0.000250784410038767 1 1 3.94778286606191 -3.83832497010942 2.60608098264178e-06 1019.31765437539 276.621126881859 3.68488721691431 0.000268871487453501 -1892.10691414753 657.034145284223 -2.87976953363518 0.00424963747365459 MAP7D1 other 0.0261155375270533 1 1 3.68488721691431 -2.87976953363518 5.08530840679316e-15 37.4922950579217 12.5370576673305 2.9905178753082 0.0030075318944077 -136.904218527451 23.2894949971889 -5.87836784541594 1.06730686734012e-08 WARS2 other 6.99331612102195e-11 0.000162198624629679 1 2.9905178753082 -5.87836784541594 0.351273762354925 -4.0979013939254 10.270384850216 -0.399001736905623 0.690159731223795 -35.1995458724729 24.3943534171333 -1.44293825995612 0.150022144468591 OSCP1 other 1 1 1 -0.399001736905623 -1.44293825995612 0.00226867195640013 135.031811297708 64.2712087254277 2.10096890933818 0.0364305547269329 -364.078885307074 152.657821791502 -2.38493436519963 0.0176677436067702 MRPS15 other 1 1 1 2.10096890933818 -2.38493436519963 0.000805279017961744 52.5569852941174 13.8479648497353 3.7952858679535 0.000176364999236969 -25.0048144257707 46.721847541755 -0.53518462435425 0.592893907098935 EXOC8 other 1 1 1 3.7952858679535 -0.53518462435425 2.03909139149743e-07 150.181657037814 26.5334207547713 5.66009405367788 3.36406491416912e-08 32.5273890806329 89.5214894547741 0.363347273137872 0.716585394481493 GNPAT other 0.00221180243235726 1 0.000426462509169219 5.66009405367788 0.363347273137872 6.48069106026967e-07 141.227891938025 26.0249994002449 5.42662421489607 1.13587721895308e-07 -68.4956771771205 87.8061193429262 -0.780078628798195 0.435921197230338 TSNAX other 0.00679824492222288 1 0.0014112138568273 5.42662421489607 -0.780078628798195 0.00485814433923778 53.8260758683796 16.8336305774644 3.1975322032098 0.00152553063306 -6.75208037386081 39.9834611447388 -0.168871833016619 0.866004817939084 C1orf109 essential 1 1 1 3.1975322032098 -0.168871833016619 6.77432397420884e-06 193.499029457907 45.1404039802075 4.28660384924224 2.40814391854395e-05 -199.614823968139 109.391210905434 -1.82477936130263 0.0689724234019775 RRAGC other 0.0656567479580321 1 0.263137885979298 4.28660384924224 -1.82477936130263 1.53803085543911e-08 110.182903905672 17.8805230135797 6.16217455283559 2.15565473593555e-09 4.93773140676326 57.421052842974 0.0859916557132136 0.931526828984572 TBCE essential 0.000176888928684052 1 2.84330859669898e-05 6.16217455283559 0.0859916557132136 0.290375839452373 311.942348753835 197.974848096384 1.5756665644818 0.116090742137969 -42.0469881951255 635.771347711061 -0.0661353934028411 0.947311331594764 NID1 other 1 1 1 1.5756665644818 -0.0661353934028411 0.0107552611242999 199.21126736252 66.3162015502528 3.0039607623118 0.00287518464079566 62.6004467175408 212.966148175328 0.293945527276964 0.768990093653961 LGALS8 other 1 1 1 3.0039607623118 0.293945527276964 0.0158529785875416 8.66597105491044 3.00632012083681 2.88258425802581 0.00421282565115967 1.10011158440304 7.52584956740953 0.146177727118948 0.883873707361333 HPCAL4 other 1 1 1 2.88258425802581 0.146177727118948 0.00195045634124711 121.017348279154 35.2465795238673 3.43344942726164 0.00067436482707391 94.1428840208723 113.189961157008 0.831724678218462 0.406184579203717 MTR other 1 1 1 3.43344942726164 0.831724678218462 0.0060359695645164 19.8188157809779 17.456785689167 1.13530727442434 0.257104252528523 141.017484018855 44.544132980831 3.16579254285946 0.00169687544784854 BMP8B other 1 1 1 1.13530727442434 3.16579254285946 0.0807141674557689 193.302834635503 96.6832420877321 1.99934166936703 0.04642464123713 336.431949376897 246.704706654351 1.3637030032356 0.173628643743271 MYCL other 1 1 1 1.99934166936703 1.3637030032356 0.304108551657716 115.567412404179 87.3378995945315 1.32322179650191 0.186706302301384 209.311055568693 280.474689918364 0.74627430956289 0.456049614154526 SIPA1L2 other 1 1 1 1.32322179650191 0.74627430956289 4.87936498158639e-06 148.797632951802 29.5368262005126 5.03769876769019 7.93960615046226e-07 82.4053440265774 75.3469770303749 1.09367817096839 0.274929146529655 RLF other 0.0478763291993257 1 0.00950529648333342 5.03769876769019 1.09367817096839 0.0027867618626421 86.6973950152517 25.045243070131 3.46163120767021 0.00061032691041762 -15.379821788051 79.1747559068532 -0.194251584509397 0.846102925391214 KMO other 1 1 1 3.46163120767021 -0.194251584509397 0.00566484321690931 0.614467736842222 1.85371263257009 0.331479500137132 0.740500665697459 -17.740853693531 5.68384929218426 -3.12127447114512 0.00196594808036853 ZNF684 other 1 1 1 0.331479500137132 -3.12127447114512 1.9505818672961e-24 41.6389933913736 3.65029759002714 11.4070133638239 1.60966577145115e-25 23.2092370948678 11.2943712577463 2.05493839056774 0.0406964597406011 KCNQ4 other 2.89973500392238e-20 1 2.42721501677119e-21 11.4070133638239 2.05493839056774 0.0505784682271084 16.7107814872347 25.5963857385095 0.652857073570877 0.514318639374842 -174.236055081902 78.4957262158573 -2.21968842740261 0.0271427654300205 RIMS3 other 1 1 1 0.652857073570877 -2.21968842740261 0.0006257224540261 210.975276115149 55.115216436324 3.82789526661651 0.000155721816141468 100.248529464157 180.781323176296 0.554529238434638 0.579607713892569 AKT3 og 1 1 1 3.82789526661651 0.554529238434638 2.10141088287111e-07 302.74502508565 54.2774066691802 5.5777356300546 5.19082389852783e-08 -247.546256498451 190.533679753784 -1.29922571599069 0.194801761729799 ETV3 other 0.00227853601426722 1 0.000653576637063639 5.5777356300546 -1.29922571599069 0.0957109890569083 85.2602912991635 55.6357350203357 1.53247353104977 0.126396725733084 -117.681224383391 117.760340048063 -0.999328163754964 0.318393171520916 ACADM other 1 1 1 1.53247353104977 -0.999328163754964 0.459801413903168 1.66004891761916 4.53262360777943 0.366244599434637 0.714424584061246 11.8417409925693 9.49055921769746 1.24773901315398 0.213038932310863 ST6GALNAC5 other 1 1 1 0.366244599434637 1.24773901315398 0.0104039144123499 -16.6625182883316 5.48074583606289 -3.04019175249716 0.00255944118412387 -1.14137195557618 19.1845875053726 -0.0594942140536795 0.952595610246847 SLAMF1 other 1 1 1 -3.04019175249716 -0.0594942140536795 0.146232341894256 -39.0682531374967 20.0133394470442 -1.9521106530408 0.0517969273801844 20.4713135877604 70.0539075120396 0.292222294441494 0.770306034449369 CD48 other 1 1 1 -1.9521106530408 0.292222294441494 0.0970705739147412 166.285172460802 94.0729373855125 1.76761964792661 0.0780804601012923 -125.747816298724 199.258309123447 -0.631079410700107 0.528440500340397 ADGRL2 other 1 1 1 1.76761964792661 -0.631079410700107 0.0764546799164465 413.560529803817 184.569333660664 2.24067845725747 0.0257326544138982 118.927946955933 359.488654139602 0.33082531419684 0.740992951325004 PADI2 other 1 1 1 2.24067845725747 0.33082531419684 3.82800868648736e-06 41.5813013440129 60.0889564639664 0.691995730845284 0.48944179971188 -534.066461402184 117.036225138023 -4.56325775008847 7.18814904722793e-06 SDHB ts 0.0378781459527924 0.106204902172793 1 0.691995730845284 -4.56325775008847 0.000140818464801442 733.193460387923 177.050788437671 4.14114767213272 4.42589560717497e-05 113.84468927905 344.844662910426 0.330133249905107 0.741515300695631 MFAP2 other 1 1 0.474500268045229 4.14114767213272 0.330133249905107 3.59172344311983e-11 40.4776702312147 21.3554755937735 1.89542349705462 0.0589401038947743 -271.162489918303 45.2335823203248 -5.99471622649842 5.51177328694365e-09 RPF1 essential 4.55610118759751e-07 8.38836776539955e-05 1 1.89542349705462 -5.99471622649842 2.17990302216258e-05 562.47630313405 125.285637305689 4.48955135824263 9.97410687193792e-06 -558.939882137964 426.115180772551 -1.31171079407357 0.190558009804463 KDM5B other 0.201728225670925 1 0.111959349637503 4.48955135824263 -1.31171079407357 0.0070832304116382 140.132581041755 48.200889202782 2.90726132566174 0.00390069170458487 -223.505182008477 165.484974379885 -1.35060710403472 0.177775642836088 UAP1 other 1 1 1 2.90726132566174 -1.35060710403472 0.427435236388666 -34.6616187281658 26.5614770929576 -1.30495825239161 0.192844668427274 -19.3383776079784 51.3807418364955 -0.376374044374783 0.706888261081928 ACTL8 other 1 1 1 -1.30495825239161 -0.376374044374783 0.000397006933633902 30.0656462224958 18.3545858883464 1.63804546751365 0.102398156702245 -114.709602192803 38.8773206239461 -2.95055318503993 0.00340685178697999 CTBS other 1 1 1 1.63804546751365 -2.95055318503993 0.462670401572235 21.0311831206301 18.8248129292772 1.11720542454483 0.26474460180466 -37.3259815183542 64.630004483979 -0.577533327072673 0.56398535676593 RGS4 other 1 1 1 1.11720542454483 -0.577533327072673 1.52813446984157e-07 149.621983618656 26.0586665420847 5.74173599316824 2.17797687290027e-08 3.93934011784447 88.6294202836594 0.0444473190193117 0.96457556632518 KLHL12 other 0.00166902846796096 1 0.000278280105050468 5.74173599316824 0.0444473190193117 0.397304365535935 -4.2620235842403 4.23666075305511 -1.00598651453669 0.315182131808035 4.51134348099283 8.19543173896954 0.55047050902044 0.582380754700894 IGSF21 other 1 1 1 -1.00598651453669 0.55047050902044 0.00030882258467813 48.6248999446317 34.392975281824 1.41380324168491 0.158394821371743 -231.320323406369 72.8486458575932 -3.17535515840008 0.00164266589964102 SSX2IP other 1 1 1 1.41380324168491 -3.17535515840008 1.69342544169591e-06 86.3161126394548 20.4293079973245 4.22511191523272 3.11813524294205e-05 -73.5072850899434 43.4120800463024 -1.69324494499094 0.0913820289154266 ZNHIT6 essential 0.0172170564657223 1 0.338099404392207 4.22511191523272 -1.69324494499094 0.127729582229368 -51.3402961576803 25.5105355630283 -2.01251345863889 0.0450059285717437 -42.8247690515301 49.737051047113 -0.861023485509117 0.38987181045487 PLA2G2D other 1 1 1 -2.01251345863889 -0.861023485509117 2.43225413417976e-07 104.290022579066 18.4952609629939 5.63874296165565 3.7661867815808e-08 -19.2334196495774 62.8104972291051 -0.306213459502197 0.7596412542678 RBBP5 essential 0.00262707769032755 1 0.000476723922812497 5.63874296165565 -0.306213459502197 0.039946406322539 63.151104137301 61.4514486103485 1.02765851034253 0.304886645820915 -248.187041420294 132.175269415444 -1.87771163635922 0.0613299707364995 GBP3 other 1 1 1 1.02765851034253 -1.87771163635922 0.105717018290842 717.914720796432 387.331544074643 1.85348890835001 0.064732549042349 -324.843737164202 833.107312339978 -0.389918240246628 0.696856401361931 GBP1 other 1 1 1 1.85348890835001 -0.389918240246628 5.84248159054755e-09 370.773252999171 92.0963670148123 4.02592702641069 7.09588403010386e-05 -641.090502078041 179.423007627737 -3.57306741512305 0.000407297386398977 PINK1-AS other 6.85790489098471e-05 1 0.746912753008732 4.02592702641069 -3.57306741512305 0.0340977947293902 12.5822916928649 5.71030432483967 2.20343627538943 0.0282783396510592 -8.09920839516109 11.1248685441373 -0.728027334707637 0.467130896021761 KIF17 other 1 1 1 2.20343627538943 -0.728027334707637 0.0439847988654324 71.585010973742 51.6080892120126 1.38708896350845 0.166379991714728 -362.934152285013 175.262720052251 -2.07080063676298 0.0391788971768932 CDK18 other 1 1 1 1.38708896350845 -2.07080063676298 0.0203550200138025 45.9355312396381 20.9985646353254 2.18755577047213 0.0294251710877857 -122.933810177948 71.3117964910722 -1.72389164523907 0.0856932188333013 RAB29 other 1 1 1 2.18755577047213 -1.72389164523907 0.369528788368889 -723.180409200714 523.045278780287 -1.38263442676919 0.167741107355737 -692.499701694958 1017.07789873347 -0.680871841338113 0.496444960638568 ECE1 other 1 1 1 -1.38263442676919 -0.680871841338113 3.45274490719806e-05 -5.19506416584402 30.6578911890538 -0.169452756349363 0.865547599043185 -266.343480211792 59.6152280025846 -4.46770882433336 1.09818280314922e-05 HMGCL other 0.313336600328224 0.161476799375061 1 -0.169452756349363 -4.46770882433336 5.2014421093875e-08 105.909382285606 55.3893888899372 1.91208793612177 0.0567576679920009 -524.847620393302 107.706398565874 -4.87294745142091 1.73305609867319e-06 GALE other 0.000582405472988118 0.0258883920019802 1 1.91208793612177 -4.87294745142091 0.574730486379938 -115.701736030381 114.941777116552 -1.0066116857847 0.314881960374855 -131.171549252111 222.058452069006 -0.590707302649074 0.555133513114136 ID3 other 1 1 1 -1.0066116857847 -0.590707302649074 0.313894063622293 -18.6041683139006 12.9225121559926 -1.43967117920436 0.150944119096741 -22.8301608374507 44.5225164005697 -0.512777863498267 0.608462719459225 CR2 other 1 1 1 -1.43967117920436 -0.512777863498267 0.260099337915525 266.093539687842 165.610980430034 1.60673850850282 0.109101089579649 -184.045925943601 561.293705830283 -0.327895937602497 0.743205446587894 CD46 other 1 1 1 1.60673850850282 -0.327895937602497 4.3178523964761e-11 157.626105085966 22.8901601362897 6.8861949478487 3.09979509046237e-11 178.947249813677 94.7845911374244 1.88793608398045 0.059950537753208 PRPF3 essential 5.46769648965769e-07 1 4.25136896656914e-07 6.8861949478487 1.88793608398045 1.95152237340529e-15 856.106162139243 98.8515496255377 8.66052343521455 2.45774269719293e-16 -372.827537521521 409.328884497535 -0.910826359051547 0.363081125345658 APH1A other 2.70188272597963e-11 1 3.57576985014599e-12 8.66052343521455 -0.910826359051547 2.24383911086796e-08 331.880340399647 54.5955834183402 6.07888623254749 3.45225524398761e-09 87.2973402953414 169.880416461522 0.51387524303082 0.607694981321418 P3H1 other 0.000256201549678904 1 4.52659707591655e-05 6.07888623254749 0.51387524303082 3.59546609740139e-17 16428.8243764627 1777.38009096384 9.24328142302625 3.50005759867562e-18 7825.96038600803 5562.08848969446 1.4070183170419 0.160395488841824 SLC2A1 other 5.07643858292102e-13 1 5.14928473917158e-14 9.24328142302625 1.4070183170419 0.00117164480336783 218.582134018066 95.5827447425483 2.28683675706129 0.0228580356539191 -737.481504728089 299.161104589071 -2.4651650679693 0.0142196181464188 CDC20 essential 1 1 1 2.28683675706129 -2.4651650679693 0.341638181677039 0.831558781289023 23.3510581354462 0.0356111820057842 0.971614595505695 106.3745020614 73.2313867021339 1.45258074238134 0.147320023382865 ARTN other 1 1 1 0.0356111820057842 1.45258074238134 2.74523585498917e-10 214.431575981603 34.0929336381956 6.28961937559305 1.04398822283727e-09 -177.857343954617 106.919043778963 -1.66347675463977 0.0971960232798154 IPO13 essential 3.39091532808262e-06 1 1.38881753284042e-05 6.28961937559305 -1.66347675463977 1.57072661455281e-06 403.118216823171 101.834370382669 3.95856738062355 9.29450386902077e-05 -886.274682717486 319.363350209014 -2.77512958871907 0.0058424208760759 ATP6V0B essential 0.0160151285619804 1 0.96662840237816 3.95856738062355 -2.77512958871907 3.05089982635847e-29 837.077834596264 67.2185050806052 12.4530861493049 2.69651602503144e-29 -117.44650701678 210.804337454196 -0.557135154025469 0.577824556838024 B4GALT2 other 4.60350274799229e-25 1 4.0916934163827e-25 12.4530861493049 -0.557135154025469 3.21139419013922e-13 272.596061127599 37.2466028706174 7.31868251379888 2.03618406460883e-12 -209.907262332259 116.809283859327 -1.79700838321249 0.07327712741852 ERI3 other 4.27275996998023e-09 1 2.84699255913606e-08 7.31868251379888 -1.79700838321249 0.246086080960611 72.5422575402458 43.5623650820378 1.66525066771816 0.096841431082955 10.8853456627412 110.561300742831 0.0984552966508668 0.921632410338167 PTCH2 other 1 1 1 1.66525066771816 0.0984552966508668 0.00144727911631268 200.137830046933 116.174353810141 1.72273676145433 0.0859052831165581 -840.763812595176 294.771283201472 -2.85225821003915 0.00462427525531879 AKR1A1 other 1 1 1 1.72273676145433 -2.85225821003915 0.10585980061369 996.912861684191 580.567228001903 1.71713595532286 0.0869249215938185 -1354.44675077796 1473.08369851164 -0.919463539068728 0.358547900985224 PRDX1 other 1 1 1 1.71713595532286 -0.919463539068728 0.249129919819409 -39.3757657354296 38.4860110340313 -1.02311891197588 0.307026865118851 -144.974497765639 97.6413752818311 -1.48476501224185 0.138593548424012 PIK3R3 other 1 1 1 -1.02311891197588 -1.48476501224185 0.633772476802556 -259.238911074497 343.074212224406 -0.755635083714563 0.450423859332926 -620.014200340698 870.628958123926 -0.712145161903109 0.476893771820435 TSPAN1 other 1 1 1 -0.755635083714563 -0.712145161903109 0.253982616847965 27.7408322047338 25.944232520082 1.06924851923298 0.285766112096147 -110.097991173204 84.0772144331321 -1.30948666550754 0.191311898109333 BLZF1 other 1 1 1 1.06924851923298 -1.30948666550754 0.000172076812790754 70.7377126228593 16.8094851921094 4.20820220336459 3.35020183013277e-05 8.7473506545554 54.4743302741214 0.160577479530959 0.872527831697922 SLC19A2 other 1 1 0.362558842056968 4.20820220336459 0.160577479530959 0.313162619580723 10.7235867146993 19.6563823510877 0.545552407516426 0.58575372041257 -65.031058300055 49.8825474985542 -1.3036835839617 0.193278581525502 FAAH other 1 1 1 0.545552407516426 -1.3036835839617 1.7883922128985e-05 54.7332537444031 16.5287074786779 3.31140555394359 0.0010344146917632 -115.773553203571 41.9453600956861 -2.76010392900353 0.0061113484413057 NSUN4 essential 0.166892761307688 1 1 3.31140555394359 -2.76010392900353 1.47463147690694e-09 208.533919353061 46.9339446096857 4.44313643541535 1.2232185862666e-05 -315.416500665418 99.5889460022878 -3.16718384245348 0.00168758700777811 TMED5 other 1.77014762487909e-05 1 0.136437801112176 4.44313643541535 -3.16718384245348 1.67935944919235e-09 236.944594342087 59.7322982062336 3.96677511928311 8.99483047162454e-05 -465.033995827274 126.745720397546 -3.66903114652442 0.000285102654739144 DR1 essential 2.01170468418751e-05 1 0.936901541924413 3.96677511928311 -3.66903114652442 0.0348486652767277 177.007692582372 166.940350966459 1.06030502246839 0.289807985795375 -668.359260940761 353.171137185865 -1.89245153572394 0.0593360671050111 CNN3 other 1 1 1 1.06030502246839 -1.89245153572394 0.00187985832529362 781.169050210281 221.058988524894 3.53375836659232 0.000470047236988575 -473.541588506491 712.777625583944 -0.664360905154032 0.506937779806752 PRRC2C other 1 1 1 3.53375836659232 -0.664360905154032 0.00166914376159213 1647.16512830558 648.601818956854 2.53956291851711 0.0115734678084006 -2263.07632571121 1380.6166304916 -1.63917794102291 0.102162001794142 F3 other 1 1 1 2.53956291851711 -1.63917794102291 0.000102527435302217 36.9273556585901 36.7593181191806 1.00457129098164 0.315864716170355 -289.475297458748 78.2460431617261 -3.69955189760119 0.000254282016236952 ABCD3 other 0.882043525904977 1 1 1.00457129098164 -3.69955189760119 0.00499549605003467 53.7452379259616 16.3982973802588 3.27748891727401 0.00116243190932925 4.67859623409215 52.8743008746917 0.0884852595059382 0.929546349477148 VAMP4 other 1 1 1 3.27748891727401 0.0884852595059382 1.43353298308941e-05 29.6633983304327 16.0625577604903 1.84674189333638 0.0657077004054951 -116.896017244658 33.2214850284672 -3.51868729361408 0.000496507015073306 DPH5 other 0.135010136347361 1 1 1.84674189333638 -3.51868729361408 0.0137194820038736 -11.8410554677488 4.0173831115835 -2.94745488265905 0.00343949794948434 0.0803076457516149 12.9535596559244 0.00619965846336962 0.995057283016611 FASLG other 1 1 1 -2.94745488265905 0.00619965846336962 0.00758483058902065 8.93490191869754 11.1417021559171 0.801933294721261 0.42318665674572 -61.4616534249144 23.5700441694045 -2.60761723580882 0.00954475150953966 PTBP2 other 1 1 1 0.801933294721261 -2.60761723580882 0.736919155039959 -56.9413145539907 83.0988327269786 -0.685223999969668 0.493700191172518 -95.4798792756537 267.733896381076 -0.356622305080689 0.721610345228572 TNFSF4 other 1 1 1 -0.685223999969668 -0.356622305080689 0.000326145408350057 710.002116524284 178.036029076207 3.98796872862386 8.2682616482059e-05 365.168172972258 573.609498431768 0.636614585306934 0.524832465134564 PRDX6 other 1 1 0.864446755319927 3.98796872862386 0.636614585306934 1.22915071167897e-06 181.235215774261 34.798930131703 5.20806861269422 3.43470414056581e-07 111.134977038236 112.029925757264 0.992011520913019 0.32194612652995 DARS2 other 0.0126528774260234 1 0.00418106535031076 5.20806861269422 0.992011520913019 0.685880995331544 -0.421353214571593 3.63264225960388 -0.115990836548144 0.90773301680548 -10.6381205751434 12.3271856926178 -0.862980475869208 0.388798571454477 HSD11B1 other 1 1 1 -0.115990836548144 -0.862980475869208 2.66517220207016e-07 1816.36790434535 333.511346515107 5.44619522941201 1.02938639544679e-07 -1539.69827422271 1132.61760576392 -1.35941580493465 0.174975038866401 IRF6 other 0.00287332215105184 1 0.00128117430777308 5.44619522941201 -1.35941580493465 8.49684885738740e-11 169.758940836531 24.0839417884594 7.04863607160338 1.11627645758606e-11 -29.0909004784237 81.7898358934584 -0.355678675236839 0.722315565660001 DIEXF essential 1.06550484671638e-06 1 1.54336383025848e-07 7.04863607160338 -0.355678675236839 0.12663850605596 0.98088586166907 6.92444836500957 0.141655451808357 0.88744158138552 28.2117306248306 14.4083314505841 1.95801510546781 0.0510996083609455 PLPPR4 other 1 1 1 0.141655451808357 1.95801510546781 9.96214924570415e-06 112.881477791045 40.1945983221982 2.80837432149941 0.00528609070633846 -242.001629330924 78.3074941511826 -3.09040190794139 0.00217494375690444 RCAN3 other 0.095128563147229 1 1 2.80837432149941 -3.09040190794139 1.64019020191992e-06 41.0722660779782 31.4567741851375 1.30567317030822 0.192604554102397 -279.636005987879 61.2843830599329 -4.5629243866975 7.20657995590766e-06 SYF2 essential 0.0166954960653429 0.106462805688624 1 1.30567317030822 -4.5629243866975 0.231486342786875 10.2114954787998 53.9523715120793 0.189268704833736 0.850002586730173 -168.342279409148 105.828287453549 -1.59071155226846 0.112664988325358 RSRP1 other 1 1 1 0.189268704833736 -1.59071155226846 0.742494873805307 19.7038396836906 36.6669931098897 0.537372661691645 0.591386042499394 -25.4555032266197 76.3015057390362 -0.333617311743254 0.738888228941828 SLC35A3 other 1 1 1 0.537372661691645 -0.333617311743254 5.72333744106865e-06 110.340044689075 22.1316957025718 4.9856118650797 1.0141575318785e-06 40.836566429364 74.6887804706983 0.546756369189679 0.584927169549416 RCOR3 other 0.0558254334001836 1 0.0120897719375236 4.9856118650797 0.546756369189679 0.0011788109326926 65.140251292873 28.5482623952375 2.28175888224076 0.0231619811730906 -123.587157925363 55.9977927640518 -2.20700052314741 0.0280258365220004 MTFR1L other 1 1 1 2.28175888224076 -2.20700052314741 0.233176954194635 -17.2385096207442 11.0113143703298 -1.56552696989505 0.118450827017929 -23.4105144688685 21.598838193123 -1.08387841325291 0.279237229509366 MAN1C1 other 1 1 1 -1.56552696989505 -1.08387841325291 0.00090994622003715 99.4874067145537 26.6465413147884 3.73359549891527 0.000223380447861078 60.3611327627949 89.9252231419554 0.671236952812552 0.502553823716187 NEK2 other 1 1 1 3.73359549891527 0.671236952812552 3.66431824967999e-08 283.276136524994 97.8647629678488 2.89456723681084 0.00405767051907711 -825.883833077727 191.969093808313 -4.30217081663362 2.24977094712003e-05 RPS6KA1 other 0.000413738173571367 0.328039101799571 1 2.89456723681084 -4.30217081663362 4.90360766196503e-13 64.2406002675495 24.2906267680306 2.64466622788416 0.00858044219585226 -306.816025674055 47.6478915115416 -6.43923615381252 4.3954759912173e-10 DHDDS essential 6.50120303823324e-09 6.71716640977828e-06 1 2.64466622788416 -6.43923615381252 0.000171242396265292 291.808360614455 71.4709418638654 4.08289513198634 5.62445666428488e-05 274.460953020509 241.196045646153 1.13791647074993 0.256006616871625 NENF other 1 1 0.596698607513983 4.08289513198634 1.13791647074993 0.392324178343831 24.3569119375868 18.3046656729081 1.33063954146054 0.184258011879818 -18.2552946100958 58.6307052514096 -0.311360651928315 0.755729840772958 NSL1 essential 1 1 1 1.33063954146054 -0.311360651928315 0.192784064341596 -20.2919605642834 11.5960880858871 -1.74989706994202 0.0810975763506347 -19.1797183926472 37.1428156505093 -0.516377610494485 0.605948463800133 PROX1 other 1 1 1 -1.74989706994202 -0.516377610494485 0.072020402009165 198.010231153826 136.170414498531 1.4541354807726 0.146888834602426 -355.737735772615 267.108510581825 -1.33180981391321 0.183870513958504 ARID1A other 1 1 1 1.4541354807726 -1.33180981391321 0.0906507102741404 258.918080521113 127.962121802501 2.0233962744126 0.0438658493726498 364.488880431819 411.158212377761 0.886493007944437 0.37601973115005 CENPF other 1 1 1 2.0233962744126 0.886493007944437 0.000331780685644293 -129.166977466073 74.6886403488187 -1.72940592923936 0.0847008117958451 -594.993113893977 149.776027386744 -3.97255237887714 8.78942014419863e-05 RPA2 essential 1 1 1 -1.72940592923936 -3.97255237887714 3.81886197534293e-07 86.3253487551947 31.9837167724127 2.69904055771448 0.00732328817710624 -261.830675319143 64.1381877734304 -4.08228988701811 5.63839783270824e-05 PPP1R8 essential 0.00407472572769091 0.811816519953333 1 2.69904055771448 -4.08228988701811 0.000733314972082446 27.1123364926959 40.5331699399012 0.668892576941194 0.504046259271318 -285.768927152417 81.2276323014516 -3.51812454771391 0.000497521528521032 STX12 other 1 1 1 0.668892576941194 -3.51812454771391 0.292252744735652 14.3702690980406 10.6814794933998 1.34534444473916 0.179469565607152 -30.0591329631855 34.7751421754336 -0.864385623832771 0.388025589769534 MARC2 other 1 1 1 1.34534444473916 -0.864385623832771 0.00272214847602811 167.272498463337 51.2469729424044 3.26404641794808 0.00121750867846635 -48.2022449561204 125.319797226437 -0.384633920760541 0.700764953450158 OSBPL9 other 1 1 1 3.26404641794808 -0.384633920760541 7.91622681853883e-05 233.859963518135 59.6885531562141 3.91800355599318 0.000109265936720582 -155.352644602627 145.25626481913 -1.0695073620134 0.285649704891498 TXNDC12 other 0.689345031358361 1 1 3.91800355599318 -1.0695073620134 2.72370529999317e-16 710.927084085348 101.175626809971 7.02666350089055 1.33426682869256e-11 -339.5764729475 229.977343505534 -1.47656489883461 0.140800886705061 ESYT2 other 3.81100845575044e-12 1 1.84195535701008e-07 7.02666350089055 -1.47656489883461 1.72761698122205e-07 139.23087165 29.2734796377519 4.75621188095605 2.98865682604306e-06 -136.705488602075 70.2262154157475 -1.94664467952263 0.0524521547098035 CD3EAP other 0.00188068384575833 1 0.0346893397798818 4.75621188095605 -1.94664467952263 0.130140321673208 118.03990645795 82.4158669321262 1.43224734328356 0.153052181856533 -127.126559855308 159.779249146827 -0.795638736157076 0.426833679715069 RCN2 other 1 1 1 1.43224734328356 -0.795638736157076 0.633364071082638 6.69106656602371 7.50715783270615 0.891291580000222 0.373442426389208 0.0969340831746895 14.609437365837 0.00663503191446385 0.994710183716581 CHRNB4 other 1 1 1 0.891291580000222 0.00663503191446385 0.141803903131736 -2795.08448504137 2009.13888936766 -1.39118529825535 0.165135706663663 1236.14538450056 3742.16488350129 0.330328946741646 0.741367582445993 MUC5B other 1 1 1 -1.39118529825535 0.330328946741646 0.00318063553959616 -180.007625498609 1139.76528578662 -0.157933942841903 0.874608464109888 -6239.82696871631 2142.92854158547 -2.91182223187886 0.00384565737490368 CTSD other 1 1 1 -0.157933942841903 -2.91182223187886 0.122130130356372 24.2895569054852 13.1546227624359 1.84646548549047 0.0657596005941824 53.3835670895121 40.5180130525608 1.31752677556676 0.188616555588993 COLEC11 other 1 1 1 1.84646548549047 1.31752677556676 8.05451162719671e-13 301.697727292458 39.0195608688764 7.73196111320424 1.39623576287578e-13 -27.4985818425582 173.493627482713 -0.158499088649801 0.87416382989516 STAG1 other 1.06319553478997e-08 1 1.98195666540217e-09 7.73196111320424 -0.158499088649801 1.18656932309832e-14 132.934213040959 68.5771887245371 1.93846110511957 0.0534516922385567 -681.595699076482 112.961642283412 -6.03386853536011 4.44975564668273e-09 STK11 ts 1.62227757854002e-10 6.7756429232038e-05 1 1.93846110511957 -6.03386853536011 1.21350555755387e-11 425.683805369698 71.8643237481127 5.92343715445979 8.16018874734852e-09 48.4520329839168 135.88124507892 0.356576310113848 0.721644749777241 KMT2A og 1.55765573367615e-07 1 0.000105723405410647 5.92343715445979 0.356576310113848 0.00013662272507588 105.660050736658 27.7271932249689 3.81070128084617 0.000166262486481903 47.9402113240594 52.4266470684144 0.914424515103924 0.361184476567525 TREH other 1 1 1 3.81070128084617 0.914424515103924 8.71913700713561e-21 93.9725259746512 17.8715925664407 5.25820659940026 2.67064858183188e-07 -120.173545799068 33.7916524196739 -3.55630865003516 0.000433100052205807 IFT46 other 1.27247085482137e-16 1 0.00326940799387859 5.25820659940026 -3.55630865003516 0.0176056701272599 -20.1037844690558 19.0462229221637 -1.05552605108184 0.291981051458112 -122.298036921807 43.13413901099 -2.8352956550413 0.00486966621030446 ZNF541 other 1 1 1 -1.05552605108184 -2.8352956550413 0.881933901604245 -0.887257696890694 14.0299291998526 -0.0632403545486187 0.94961459455695 -15.8180488144939 31.7736970156201 -0.497834696627141 0.618942495446119 SLC8A2 other 1 1 1 -0.0632403545486187 -0.497834696627141 4.9226943292616e-05 53.3903169705782 14.8667145094479 3.59126536913373 0.000380746571591952 -60.4845457395233 33.6687716461096 -1.79645834351406 0.0733646906478472 KPTN other 0.439842738319524 1 1 3.59126536913373 -1.79645834351406 7.33548059252212e-16 624.193290592513 226.957591333918 2.75026398951401 0.00629455657796433 -2036.79686215461 428.153071305704 -4.75716980364793 2.97915996689626e-06 RPS25 essential 1.02065876964353e-11 0.0443239419874825 1 2.75026398951401 -4.75716980364793 0.00208215026694334 81.3568251320545 22.9280873585394 3.54834766022268 0.000445887275804676 4.30325888857935 77.7658711236581 0.0553360854369726 0.95590535509958 KIF14 other 1 1 1 3.54834766022268 0.0553360854369726 0.122405025295617 55.1670159889811 27.8179798763779 1.98314242206448 0.0482087953936887 54.5516134413523 92.7399466618989 0.588221315677812 0.5567999619484 TNNT2 other 1 1 1 1.98314242206448 0.588221315677812 3.53618778245466e-05 55.9581595774256 12.2015001132671 4.58617047559428 6.49367481172567e-06 -12.9437617767894 41.3841883313581 -0.312770705399614 0.754659245503313 DDX59 essential 0.32052006060169 1 0.0738482662956293 4.58617047559428 -0.312770705399614 0.0532127400293623 187.999546561024 79.3358659736493 2.36966653421879 0.0183989027035486 -139.561980600237 268.887498292526 -0.519034843518108 0.604096333336802 CAMSAP2 other 1 1 1 2.36966653421879 -0.519034843518108 3.93198380367267e-08 234.564381505106 40.2035298401103 5.83442256035653 1.3219429116377e-08 -216.073364986983 138.028161214661 -1.56542956948435 0.118470552938202 ATF6 other 0.00044313457467391 1 0.000170147272156888 5.83442256035653 -1.56542956948435 2.33203885620985e-07 114.710693983273 66.1738604830351 1.73347441340045 0.0839746103826421 -464.050098584475 116.102327869633 -3.99690606639291 7.97146530018589e-05 MREG other 0.00252140041133409 1 1 1.73347441340045 -3.99690606639291 3.62234964358434e-15 161.957554546132 27.0301364872133 5.99174016833939 5.63601201908184e-09 -163.716602129719 50.9508795790711 -3.21322425603361 0.0014475106197134 FASTKD2 other 4.98978663403743e-11 1 7.34485086326745e-05 5.99174016833939 -3.21322425603361 1.89841834117463e-05 633.833913629415 163.945407382853 3.86612790042516 0.000134246387396808 -314.538895135734 313.711945072085 -1.00263601713814 0.316803648436999 NRP2 other 0.176609858279475 1 1 3.86612790042516 -1.00263601713814 8.72971341948801e-07 126.831413813562 36.4054119688296 3.48386151823128 0.000563988502544164 -156.680085854885 68.5177301088908 -2.28670864615456 0.0228739080747559 CREB1 other 0.00907890195626753 1 1 3.48386151823128 -2.28670864615456 1.29521282138302e-05 358.491169678034 91.6304269466964 3.9123594817099 0.000111938427752147 -174.877437086529 173.553581640859 -1.00762793503398 0.314404047749518 KLF7 other 0.122462372261765 1 1 3.9123594817099 -1.00762793503398 2.77768117242176e-05 24.164489969708 11.5991096749494 2.08330558524643 0.0380218155046019 -46.5861447141439 20.7217321442775 -2.24817811512003 0.0252495282184658 B4GALT6 other 0.254796693946248 1 1 2.08330558524643 -2.24817811512003 3.18927869025228e-05 34.4303827966386 7.80058706343225 4.4138194364937 1.39561208298543e-05 -47.5767825936112 32.3010171635765 -1.47291902148704 0.14176820835964 C1orf54 other 0.290447610321275 1 0.154996677936362 4.4138194364937 -1.47291902148704 0.00941031233545741 3.28358465472489 1.18131295207925 2.7796060721635 0.00576853002973637 -6.7322182352034 4.8916331079161 -1.37627211335795 0.169711876201605 CA14 other 1 1 1 2.7796060721635 -1.37627211335795 0.207229363623891 62.9247896587926 38.4517475335245 1.63646111542606 0.102744971950015 -68.8056948216396 182.066114586015 -0.377915983861638 0.705748346363186 LRMP other 1 1 1 1.63646111542606 -0.377915983861638 0.100789174449342 -58.484350824578 85.6524667203441 -0.682809883520691 0.495222544181833 -264.294248474678 122.945644711153 -2.14968370043206 0.0323319058410196 ATP10B other 1 1 1 -0.682809883520691 -2.14968370043206 7.30408123854594e-38 213.027845716344 17.8565202723377 11.9299752957105 2.52068253538088e-27 -180.642521957941 61.0133451041426 -2.96070509901736 0.00330246499140113 SPCS2 essential 1.11409151131541e-33 1 3.81278440301713e-23 11.9299752957105 -2.96070509901736 2.53401498694108e-19 43.2966585167075 7.12413997106428 6.07745758681933 3.50137154747289e-09 -92.3027358570105 23.0183665600854 -4.00996029045199 7.5785507520719e-05 USP35 other 3.65709042915337e-15 1 4.59029809873696e-05 6.07745758681933 -4.00996029045199 0.00168344148781113 140.258965499008 38.8793387421471 3.60754503643244 0.00035868403193959 91.4621612529207 83.3197254772465 1.0977251872715 0.273152393454548 ELOVL4 other 1 1 1 3.60754503643244 1.0977251872715 0.902863736901025 3.434711643091 25.2368898684655 0.136098848193763 0.891829253775245 -23.7247914399707 60.1267619477092 -0.3945795627678 0.693417699719833 FILIP1 other 1 1 1 0.136098848193763 -0.3945795627678 0.00489533784483908 46.6783515897822 24.474252972179 1.90724316051009 0.0573842757745259 -121.282968372734 58.5483342029881 -2.07150160672794 0.0391129634752315 CASP8AP2 other 1 1 1 1.90724316051009 -2.07150160672794 0.889180541771172 39.1719180875286 84.8845358458675 0.461472960854219 0.644773825859382 -8.57439288490912 195.597375246057 -0.0438369526897932 0.965061798196636 HMGN3 other 1 1 1 0.461472960854219 -0.0438369526897932 0.0278048670412356 6.81679934811515 4.11189003850543 1.6578262755764 0.0983448697605408 -14.2569972554751 8.77974337521691 -1.6238512501082 0.105404613699398 UBE3D other 1 1 1 1.6578262755764 -1.6238512501082 0.267984945204683 -2.58287168122153 3.83389248293988 -0.67369434398978 0.500993489430632 11.4484144572867 9.23635670569842 1.2394946213179 0.216073474714851 CNR1 other 1 1 1 -0.67369434398978 1.2394946213179 2.98056809503598e-08 61.25753954045 15.135963365927 4.04715167838927 6.51107918247988e-05 -103.279786386408 32.8345146249696 -3.14546408150241 0.00181443280947801 ANKRD13C other 0.000338234867424683 1 0.687895515628999 4.04715167838927 -3.14546408150241 0.00495102573395929 17.1376044428208 8.4132040497934 2.03698904025057 0.042473790435704 57.6360652427834 19.0110017117239 3.0317216376473 0.00263026236316782 SGIP1 other 1 1 1 2.03698904025057 3.0317216376473 0.127199206396086 93.9186661990621 71.2549418106152 1.31806529922772 0.188536488140892 -244.786791810543 180.794953373258 -1.35394703913649 0.17682217104885 PHF3 other 1 1 1 1.31806529922772 -1.35394703913649 0.127950779358767 41.2050891504947 22.669545715919 1.81764070911927 0.0700570465141036 -23.2724294958025 49.8039729282383 -0.467280582802808 0.640618168282184 PLAGL1 other 1 1 1 1.81764070911927 -0.467280582802808 2.21136988633735e-07 67.7668043496179 24.3040080806343 2.7882974744242 0.00561762695146482 -224.053501899784 53.8010990341566 -4.16447815977773 4.02392872490856e-05 FBXO30 other 0.00239402903894881 0.582302725781518 1 2.7882974744242 -4.16447815977773 0.370217844714031 -208.820923098375 243.180437195407 -0.858707737788039 0.391150616901665 -722.729370225398 563.254742026833 -1.28313055585596 0.200383625038078 TNFAIP3 ts 1 1 1 -0.858707737788039 -1.28313055585596 0.170758361289889 -9.42202038338006 8.97334156785802 -1.05000130799982 0.294509832296467 -37.5026339934781 21.1743318430637 -1.77113659460113 0.077489801404687 AKAP7 other 1 1 1 -1.05000130799982 -1.77113659460113 0.136245519071398 47.2612282259867 36.5354626200533 1.293571364279 0.196749386490189 -93.6795154005001 80.0050780255318 -1.1709196180098 0.24250500834349 RAB32 other 1 1 1 1.293571364279 -1.1709196180098 0.126090427853546 -80.0353539693728 39.7904912082442 -2.01141909886225 0.0451245979565858 -73.1369493228084 92.6411018585811 -0.789465451678822 0.430428248393731 MYB other 1 1 1 -2.01141909886225 -0.789465451678822 0.648476849896989 -8.01608638166592 14.4113199651739 -0.556235403907304 0.578439892269361 -28.75201594351 33.7238465757356 -0.85257225562748 0.394536201277788 ALDH8A1 other 1 1 1 -0.556235403907304 -0.85257225562748 0.268790318249896 -571.411402476987 564.389680275276 -1.01244126610941 0.31209682628679 -1932.94456301326 1326.19807976927 -1.45750819014121 0.145962949929975 SGK1 other 1 1 1 -1.01244126610941 -1.45750819014121 0.000152065639027744 26.66044346046 14.1746339912789 1.88085586385251 0.0609080099482966 -109.135356681946 33.3678801996482 -3.27067095748852 0.00119102119482295 RNF146 other 1 1 1 1.88085586385251 -3.27067095748852 0.349905256401144 39.9164652657145 27.569558599915 1.44784564181733 0.148639239038384 15.8849914406727 65.0556961580967 0.244175258720918 0.807251567555841 ARG1 other 1 1 1 1.44784564181733 0.244175258720918 0.00852962979614805 1354.6879369145 498.921220999923 2.71523414898944 0.00698468051378999 -992.242536618152 1192.17510629024 -0.832295970099367 0.405866496703351 CTGF other 1 1 1 2.71523414898944 -0.832295970099367 4.66029723312963e-05 39.7623181126343 12.6116906780461 3.15281425208523 0.00177121788723458 -58.4148939488586 34.8748442738402 -1.67498651722084 0.0949199172214648 PMFBP1 other 0.417516029116083 1 1 3.15281425208523 -1.67498651722084 8.81811303001277e-08 125.581050981156 71.4200818941414 1.7583436990074 0.0796479555307536 -481.02027467776 133.265382477143 -3.60949157040286 0.000356108905226653 FBXL5 other 0.000976517836943614 1 1 1.7583436990074 -3.60949157040286 1.20090685791517e-13 229.192495565562 40.9728456322721 5.59376562766827 4.79403457194457e-08 -127.814502367372 76.9343356224108 -1.66134537113153 0.0976296075403928 MED28 essential 1.61125673126478e-09 1 0.000604527759522211 5.59376562766827 -1.66134537113153 0.52869980819022 -29.5608844111496 27.56538041481 -1.07239167268185 0.284352215545932 14.802977561777 90.8000047120925 0.163028378783835 0.87059899648 SLC16A7 other 1 1 1 -1.07239167268185 0.163028378783835 1.11611240783863e-13 96.2701789439807 11.908292958345 8.08429716003225 1.3223604214129e-14 24.7854116322706 40.0064964871515 0.619534670831042 0.536007812657581 TMEM5 other 1.49849251876415e-09 1 1.89851285702249e-10 8.08429716003225 0.619534670831042 5.21158017189276e-06 42.125594225014 13.2743802352624 3.17345092414263 0.00165361724292864 -79.0607919087579 30.1463167097241 -2.62256887532982 0.00914712800239815 ZNF430 other 0.0509848888216268 1 1 3.17345092414263 -2.62256887532982 0.173822098008494 46.4736869993721 146.754734002589 0.316675896796297 0.751697978459769 -1113.02433036306 612.681385862795 -1.81664459871857 0.0702158433435456 VAMP8 other 1 1 1 0.316675896796297 -1.81664459871857 5.33524428845433e-11 29.8855111131914 18.877396721458 1.58313731253105 0.114381045726498 -185.644367566287 34.3948275348603 -5.39745016538113 1.32135403179366e-07 DCLRE1B essential 6.73627943860244e-07 0.00199564099421797 1 1.58313731253105 -5.39745016538113 8.46895026160853e-51 3776.43366606101 206.129974242741 18.320642982344 7.69667309798504e-51 -251.563918094407 955.734677146302 -0.263215225009459 0.792565383361236 MYL12B other 1.29829007510459e-46 1 1.18013088611405e-46 18.320642982344 -0.263215225009459 0.000105437399793172 127.776524318979 75.9203293194564 1.68303437912292 0.093346812414918 -593.29382648566 172.924132182559 -3.43094869985705 0.000680644344982615 FOXO3 other 0.905812701623139 1 1 1.68303437912292 -3.43094869985705 0.00898315776327107 1.9859570259822 2.86320002841199 0.693614489478638 0.488428742182318 -17.8178297221972 6.52152571803105 -2.73215662907433 0.00664262325845016 ARMC2 other 1 1 1 0.693614489478638 -2.73215662907433 1.20922778375586e-17 1835.82543629548 206.185253129157 8.90376692044746 4.2684573443168e-17 -1192.46265619136 1078.85776577742 -1.10530108232764 0.269867326696881 RPN2 essential 1.71794991238196e-13 1 6.23792356298458e-13 8.90376692044746 -1.10530108232764 0.0817111251402804 92.1961433737531 44.0034444713841 2.09520287516831 0.0369511682829841 -94.958065493034 240.457545941186 -0.394905741557639 0.693179717230251 TGIF2 other 1 1 1 2.09520287516831 -0.394905741557639 0.0851819139158766 139.51324590287 68.9529756409603 2.023310011004 0.0438747890484238 220.53446360392 126.729033416924 1.7402047317633 0.0827874240223364 CASQ2 other 1 1 1 2.023310011004 1.7402047317633 0.13586946585415 52.6581854147819 26.2772779977015 2.0039436892736 0.0459186256397069 38.0152041661054 48.5085877679612 0.783679878456771 0.433807628573013 PKD2 other 1 1 1 2.0039436892736 0.783679878456771 0.166705570876254 6.41268553991876 6.64231165422528 0.965429789166779 0.335058617343214 23.1255871821035 12.2618924946992 1.88597210358032 0.0602041927614483 ABCG2 other 1 1 1 0.965429789166779 1.88597210358032 0.509579569840425 1575.5273954142 1369.95694389603 1.15005614040215 0.250979486544758 795.649117782955 2528.97871146021 0.3146128174893 0.753260677026502 SPP1 other 1 1 1 1.15005614040215 0.3146128174893 0.000690831671579171 91.2296902596333 27.0323099484372 3.37483886629183 0.000830357681388896 -30.8271455659041 55.428759776531 -0.556157952842317 0.578495228700312 STBD1 other 1 1 1 3.37483886629183 -0.556157952842317 2.08461938064604e-06 888.061890042482 246.469677068923 3.60312838724637 0.000365091704859181 -990.779134283305 466.680330194122 -2.12303598454895 0.034527877559755 CCNI other 0.0210171325956734 1 1 3.60312838724637 -2.12303598454895 0.497695001994016 -27.9456978855769 38.999204507014 -0.716570972122029 0.474173181966648 210.204438705271 226.021726711206 0.930018727685657 0.353078097802231 RARRES1 other 1 1 1 -0.716570972122029 0.930018727685657 2.30423806965767e-10 316.979862043118 46.0937222450903 6.87685538515782 3.31385069113641e-11 191.626368119879 267.182716313327 0.717210943746666 0.473777122086823 MFSD1 other 2.85402927307799e-06 1 4.54229514234068e-07 6.87685538515782 0.717210943746666 4.44597160909458e-06 173.770804654057 34.7178752501503 5.00522579224672 9.24307610579671e-07 -107.576208076623 113.02919680733 -0.95175592780684 0.341941340712623 RAB3GAP2 other 0.0437439146618816 1 0.0110399301007636 5.00522579224672 -0.95175592780684 2.67944739877774e-06 99.3342784028139 21.4752059108423 4.62553322260172 5.43837784595324e-06 -61.9130828644219 62.7446784710763 -0.986746356393591 0.324514827093938 EEF2KMT other 0.0268212684617652 1 0.0621552204013996 4.62553322260172 -0.986746356393591 0.159413096747094 1334.60440647878 1003.59604530994 1.32982230521507 0.184526894527071 -2912.36753747212 2964.47330194184 -0.982423264046404 0.326635874706242 PPL other 1 1 1 1.32982230521507 -0.982423264046404 9.60329251955218e-08 249.245278182059 63.4071580791851 3.93086972721269 0.000103836622303511 -581.177414896231 187.295304875081 -3.10300044778942 0.002087071588152 UBN1 other 0.0010614519221861 1 1 3.93086972721269 -3.10300044778942 0.263548319718292 27.368064048324 17.1915896016362 1.59194493833887 0.112464407591077 28.1203887602487 35.7427311263524 0.786744265871616 0.432061016229847 KLF12 other 1 1 1 1.59194493833887 0.786744265871616 2.76311000287586e-25 265.773383880463 28.5913450360487 9.29558870159376 3.32080612908e-18 -265.150886930996 59.4437618535865 -4.46053342963183 1.16250344278757e-05 UCHL3 other 4.12394167929222e-21 0.170829880917633 4.88689829955413e-14 9.29558870159376 -4.46053342963183 0.737878616045329 4.7369276407845 13.1910554111149 0.359101489088819 0.719759753051677 19.1074844894625 24.6155628032941 0.776235938302638 0.438192126881579 PCDH17 other 1 1 1 0.359101489088819 0.776235938302638 3.89695085704635e-11 159.936212052931 24.0665456613306 6.64558239074219 1.31233171985236e-10 -120.979302130947 79.0314896171991 -1.53077340079161 0.126819556424616 HS1BP3 other 4.94094399164906e-07 1 1.77939057894782e-06 6.64558239074219 -1.53077340079161 0.000126422268442045 60.2525502888281 15.9899311162247 3.76815571317196 0.000195964855036064 -71.7082662718082 52.5089097860076 -1.36563997546407 0.173017140378203 LDAH other 1 1 1 3.76815571317196 -1.36563997546407 0.0151556543779111 35.6832296499369 12.6256918688342 2.82623954557444 0.00500787589156299 -6.32328884738189 40.9465732035316 -0.154427790964361 0.87737040523776 WDR35 other 1 1 1 2.82623954557444 -0.154427790964361 0.00011027479224609 457.760920219444 118.528710465589 3.86202565118042 0.000136498411936806 -765.165223507768 573.349087069563 -1.33455383598602 0.182986267817144 CCND2 og 0.945275519133485 1 1 3.86202565118042 -1.33455383598602 2.13377423333334e-05 663.317526053191 195.834774085675 3.38712840531069 0.000794708004606412 -451.547812143647 278.273737526934 -1.62267491052741 0.105646728282526 ELL2 other 0.197651507233667 1 1 3.38712840531069 -1.62267491052741 1.59477608921877e-13 44.4614495190268 7.44398686802075 5.97280063859764 6.27507011445909e-09 -48.6768325363903 16.3080620591056 -2.98483243195727 0.00305875491085077 CYP20A1 other 2.13572413868177e-09 1 8.16449372592273e-05 5.97280063859764 -2.98483243195727 7.1200790297257e-12 165.019197451027 27.5735649776744 5.98468850816494 5.87698815297037e-09 -178.43461338299 68.0741588046171 -2.62117985027364 0.0091863664123477 NDUFB3 other 9.19415805108479e-08 1 7.65477706924391e-05 5.98468850816494 -2.62117985027364 4.73001422586291e-12 211.187250996016 31.0309807020089 6.80569051374983 5.03498616793768e-11 -118.508940428761 77.7384845214676 -1.52445653087095 0.128391706917156 GTF3C3 other 6.13766645947972e-08 1 6.87325961785173e-07 6.80569051374983 -1.52445653087095 0.000310690756129782 37.7792981500163 9.30156522287788 4.06160654091801 6.16122998972255e-05 31.3545176860728 21.9935283032993 1.42562472258575 0.154970018028903 SATB2 other 1 1 0.652042969812337 4.06160654091801 1.42562472258575 2.33083076871618e-08 240.038033390172 52.1136235356906 4.60605149104205 5.9382021664885e-06 -156.457486032586 77.8192149429168 -2.01052511448944 0.0452169160894659 UBE2B other 0.000265971099018204 1 0.0676776900914695 4.60605149104205 -2.01052511448944 0.343664607033337 -1.4417413756356 4.87482847303641 -0.29575222669067 0.767611131600475 -13.7412986263599 9.38635909823084 -1.46396472610449 0.144185218548184 TRPM6 other 1 1 1 -0.29575222669067 -1.46396472610449 0.457090180406528 -34.734989828806 41.905816667371 -0.828882303010972 0.407788835270074 -87.3542818529736 80.6885915515234 -1.0826100713035 0.279796631740862 GDA other 1 1 1 -0.828882303010972 -1.0826100713035 0.140069839728914 48.0317707408381 57.8554015435391 0.830203740003286 0.407044474697182 216.730610436587 112.308715494149 1.92977552528305 0.0545211490534581 KLF9 other 1 1 1 0.830203740003286 1.92977552528305 1.10201608691483e-06 317.011746001074 88.8048708736719 3.56975628568882 0.000412459031087788 -563.677713145805 172.63790710657 -3.26508657683068 0.00121357719407494 TJP2 other 0.0113783160973956 1 1 3.56975628568882 -3.26508657683068 0.371747094215359 11.7327460734238 9.18996939993529 1.27669043963372 0.202637244791665 -11.7556298451024 28.9446397370137 -0.406141860873451 0.684909827112486 C2orf40 other 1 1 1 1.27669043963372 -0.406141860873451 3.62661470940993e-09 228.174572368195 47.5476071361116 4.79886551840587 2.45839342937704e-06 -435.453910219726 144.483559935533 -3.0138647636729 0.00278682460317339 ITGB1BP1 other 4.29391181594136e-05 1 0.0286747009602538 4.79886551840587 -3.0138647636729 2.20692177977443e-12 191.656284448962 31.4576152311018 6.09252427563146 3.19875952627119e-09 -279.854035970653 94.6884225074755 -2.9555253806088 0.00335387378124765 CPSF3 essential 2.88444676616518e-08 1 4.19901163013619e-05 6.09252427563146 -2.9555253806088 7.20820128132399e-10 44.1712680298906 6.83106483232639 6.46623463751369 3.75428334715542e-10 76.3893135607946 41.9289954374882 1.82187321121688 0.0694076092365967 PIGZ other 8.76517275808998e-06 1 5.04463053357274e-06 6.46623463751369 1.82187321121688 1.72239999133067e-31 321.77604124428 24.1084833749951 13.3470047136196 1.31022232114113e-32 53.53095985634 147.977586839953 0.361750458292288 0.717777266920026 SENP5 other 2.60840254687116e-27 1 1.99455143947314e-28 13.3470047136196 0.361750458292288 0.00310729397504053 114.669013120588 38.238558961709 2.99877966728334 0.00292314845895421 -112.67967437619 98.7996212350867 -1.14048690640298 0.25493635729061 CCDC92 other 1 1 1 2.99877966728334 -1.14048690640298 4.55945448212263e-11 335.291196165965 46.792723617706 7.16545587098703 5.37588760496389e-12 -27.0266591011418 157.8746424224 -0.171190627490581 0.864182074342342 C1orf198 other 5.76816586533334e-07 1 7.46549511701335e-08 7.16545587098703 -0.171190627490581 7.62863469756946e-11 500.954526467326 70.7726844542829 7.07835982667759 9.27629551252669e-12 -115.723293178237 227.277583032786 -0.509171611357482 0.610982852797541 HEATR1 essential 9.58080231667749e-07 1 1.28393206188882e-07 7.07835982667759 -0.509171611357482 1.15464111143627e-07 835.57629995924 163.007565305986 5.12599705658296 5.14048228276198e-07 -718.559129538306 325.927428908603 -2.20465988991618 0.0281914336213541 PTBP3 other 0.00126975883024647 1 0.00620867450111991 5.12599705658296 -2.20465988991618 5.54843016119557e-15 1034.57996492853 133.626988995681 7.74229796468712 1.29450064876284e-13 -759.702527904477 267.49043194533 -2.84011103641922 0.00479856367935156 RAD23B other 7.62798178561166e-11 1 1.83883817156762e-09 7.74229796468712 -2.84011103641922 1.89290407282777e-16 612.19923006006 73.6855479700168 8.30826731870364 2.79026070470798e-15 -402.756308657359 147.464103898765 -2.73121592312292 0.00666006160174568 FKBP15 other 2.65290505806812e-12 1 4.02885743152786e-11 8.30826731870364 -2.73121592312292 0.0403622303079046 223.426399460333 88.5300550798564 2.52373501020412 0.0120983339936589 -18.6773199110896 177.631250820579 -0.105146587803714 0.916325782714467 CTNNAL1 other 1 1 1 2.52373501020412 -0.105146587803714 3.8394493483743e-08 100.545681188495 17.6430491245868 5.69888347974828 2.75115449088606e-08 -47.971245254477 35.3999201905202 -1.35512297757449 0.176340183829784 FAM206A other 0.000433013097509654 1 0.000350249478234705 5.69888347974828 -1.35512297757449 1.86668498883606e-07 281.285521163505 115.623041698964 2.43278084567141 0.0155309559071954 -1089.59109596781 225.852242928339 -4.82435366521255 2.17711792604992e-06 WDR34 other 0.00202927325136368 0.0324673596311825 1 2.43278084567141 -4.82435366521255 2.71485084690492e-16 1649.32478301946 203.149052877747 8.11879139801855 1.02762046611757e-14 -1103.64470684086 396.821157504786 -2.78121437319668 0.00573659950096227 SET other 3.79889079007406e-12 1 1.47658784776433e-10 8.11879139801855 -2.78121437319668 6.76913609658206e-18 888.024587639878 104.671196098391 8.48394420567366 8.19413527029726e-16 -648.372353722321 204.548712804934 -3.1697699038597 0.00167309810059568 PTPA other 9.64398819680046e-14 1 1.18782184878229e-11 8.48394420567366 -3.1697699038597 7.24288159350922e-12 226.723529818476 38.8612107335278 5.83418595403844 1.32363910491308e-08 -296.220270660042 75.909537390736 -3.90228001437132 0.000116196511377251 GLE1 essential 9.3505601372204e-08 1 0.000170352352802314 5.83418595403844 -3.90228001437132 1.10913274065318e-14 490.927325322241 75.4259888332015 6.50872905899699 2.93776806854143e-10 -687.305869276578 150.702359814639 -4.56068418651143 7.27912381522987e-06 RAB14 other 1.51762632903575e-10 0.107512658750945 3.95599848109789e-06 6.50872905899699 -4.56068418651143 0.000123529974452771 37.7382542598978 26.2990765760156 1.43496499395399 0.152279828489791 -203.196812564496 52.6136708153399 -3.86205351984779 0.000136241531419813 CNTRL other 1 1 1 1.43496499395399 -3.86205351984779 5.72878135571343e-09 111.90655920357 18.0233727051534 6.20896882255413 1.6539243250138e-09 -20.9612165121974 35.981658185485 -0.582552821888934 0.56060461899406 TRIM32 other 6.72845370228542e-05 1 2.18781109712826e-05 6.20896882255413 -0.582552821888934 2.78772650243157e-09 262.586258085627 54.3088795370331 4.83505202692628 2.07630358781375e-06 -403.724644232463 108.649803807838 -3.71583408421523 0.000239211332991786 FBXW2 other 3.31544312934187e-05 1 0.0243155913168868 4.83505202692628 -3.71583408421523 3.93633497408625e-07 154.54897937904 43.9519902661134 3.51631356039401 0.000501423869153841 -341.232495676324 88.0444888315994 -3.87568262596188 0.000129238903304378 PHF19 other 0.00419337764789409 1 1 3.51631356039401 -3.87568262596188 1.05547277936215e-08 181.974447242945 29.1660783363361 6.23924975941093 1.39691206421286e-09 48.8118118473742 57.3487977941916 0.851139234383706 0.395330462200688 NEK6 other 0.000122297630944692 1 1.85146724990772e-05 6.23924975941093 0.851139234383706 0.00274239429739633 77.8283098728454 30.8036334255932 2.52659511939853 0.011999176206655 -131.651102922768 61.6461480584971 -2.13559333501003 0.0334714415536349 BSPRY other 1 1 1 2.52659511939853 -2.13559333501003 9.40217461777188e-11 247.721309029353 39.5668285867273 6.26083307350166 1.24359566378133e-09 -190.454049920548 77.7458483933638 -2.44970058024095 0.0148381587718546 PPP6C other 1.17658813166797e-06 1 1.65124632236886e-05 6.26083307350166 -2.44970058024095 3.61920467076665e-07 172.009464652512 36.2708838038353 4.74235658504475 3.18612475723762e-06 -167.226231129615 72.5234963609258 -2.30582141679139 0.0217596150855425 NDUFA8 essential 0.00387038732040351 1 0.036927185936384 4.74235658504475 -2.30582141679139 0.0027783150981622 79.1760405529197 24.4093863389501 3.24367189955032 0.00130459012808262 -44.6550643040254 48.8495828877692 -0.914133993868881 0.361334701987852 HDHD3 other 1 1 1 3.24367189955032 -0.914133993868881 1.07738555486953e-09 124.895395275958 19.9885176321947 6.24835706049527 1.32179676857595e-09 -57.303291427084 39.9669661648963 -1.4337663557114 0.152615329756277 RBM18 other 1.29997341050557e-05 1 1.75349559319286e-05 6.24835706049527 -1.4337663557114 7.34065975416381e-05 134.213117844404 38.2643181103374 3.50752671084828 0.000516993641149353 -181.973299274144 76.5769345127788 -2.3763460947079 0.018073136198 HSDL2 other 0.642234321891792 1 1 3.50752671084828 -2.3763460947079 1.7462926250347e-12 362.170744161957 49.7958491641707 7.27311111751354 2.75361897753426e-12 -154.659985323494 97.7882832996132 -1.58157992046585 0.11473955980757 MAPKAP1 other 2.28746870953296e-08 1 3.84267528314905e-08 7.27311111751354 -1.58157992046585 0.971187966264617 -2.68551885091469 66.6242506746664 -0.0403084285934918 0.967872370861848 29.5268224219267 127.541826936764 0.231506974073425 0.81706893096325 NR4A3 other 1 1 1 -0.0403084285934918 0.231506974073425 2.16206090126932e-09 61.9733977121483 9.54386651679742 6.49353148465286 3.21188482349907e-10 4.51500440266493 18.2797018865486 0.246995516157042 0.805070574619745 INVS other 2.58128451002544e-05 1 4.32030627608861e-06 6.49353148465286 0.246995516157042 0.268185065206527 5.22787787792624 23.3234336355204 0.224147008524699 0.822785958138706 -69.6620205097041 44.3614207258551 -1.57032888870268 0.117326847727388 GALNT12 other 1 1 1 0.224147008524699 -1.57032888870268 2.59003269781507e-09 127.315118674758 26.1616362775992 4.86648148930082 1.78907497420497e-06 -187.234333231878 51.4412109693902 -3.63977304778635 0.000318220042144222 DENND1A other 3.08498794636753e-05 1 0.0210241513112079 4.86648148930082 -3.63977304778635 2.16321646579328e-10 141.52476108323 21.9545820208111 6.44625167307112 4.21921642746849e-10 -69.8729880872028 42.028652813532 -1.66250839390945 0.0973900310811086 ALG2 essential 2.68238841758367e-06 1 5.66471997551919e-06 6.44625167307112 -1.66250839390945 0.0909106568558229 -23.846867303042 16.1251046753629 -1.47886589161042 0.140166017232387 -71.7935764444277 38.3005610866468 -1.87447845168665 0.0617810811412688 CSF3R other 1 1 1 -1.47886589161042 -1.87447845168665 1.42424317373554e-20 340.607256742078 70.2724939180566 4.84694989108048 1.96106498925409e-06 -485.284062734328 113.876346134367 -4.26150012015423 2.67654293030247e-05 KDSR other 2.07540715276742e-16 0.389490527217615 0.0229954480639934 4.84694989108048 -4.26150012015423 3.6454546728559e-15 225.862373649286 97.2894373955364 2.3215508249989 0.020886759084788 -814.192758970231 157.657214513987 -5.16432287276012 4.25741981179873e-07 VPS4B other 5.02124926639171e-11 0.00640613959081355 1 2.3215508249989 -5.16432287276012 0.00328416850748944 45.2893608488799 15.4289929973542 2.93534133152088 0.00357372033880529 10.0024365395872 23.4804866092736 0.425989320665816 0.67040290830494 ONECUT2 other 1 1 1 2.93534133152088 0.425989320665816 1.0793745555598e-09 44.2562585222248 35.2488764369331 1.25553671480586 0.210205754892282 -288.258702254701 58.0368090012215 -4.96682548912422 1.11293995747716e-06 C19orf25 other 1.30226540128289e-05 0.0166618241033906 1 1.25553671480586 -4.96682548912422 5.62142658850947e-11 62.2515495106351 11.1142373887465 5.60106351279365 4.68985249776247e-08 -70.2233975160961 28.3573150949199 -2.47637681074667 0.0138041064349505 ZBTB45 other 7.09311606938125e-07 1 0.000591718689642691 5.60106351279365 -2.47637681074667 2.69989626741517e-08 259.377657920921 44.0171702555472 5.8926472650348 9.6306089829517e-09 -9.12268556390316 143.663132733305 -0.0635005334377501 0.949407581336797 YLPM1 other 0.000307032203530453 1 0.000124465990495668 5.8926472650348 -0.0635005334377501 1.82147548635101e-14 115.856430454663 14.34208964419 8.07807183812973 1.36798425678707e-14 -10.9357571586434 44.1700236236996 -0.247583230921702 0.804616165587316 DCAF4 other 2.48121390750735e-10 1 1.96360460219216e-10 8.07807183812973 -0.247583230921702 6.38941932412168e-10 5.26838969159699 0.794199452116742 6.6335851498706 1.39780090503281e-10 1.09148948421021 2.59210623135835 0.421082080281191 0.67397782194022 PROX2 other 7.78231273678021e-06 1 1.89374066613845e-06 6.6335851498706 0.421082080281191 2.61218763565409e-26 333.703865275605 29.1713717452377 11.4394300065811 1.23492809027164e-25 -66.1748831820262 95.2094518279604 -0.695045312324679 0.487531279058313 FCF1 essential 3.9109673281013e-22 1 1.86288902417477e-21 11.4394300065811 -0.695045312324679 0.0737103773953326 229.853705652721 112.497715932528 2.04318553267853 0.0418529038883682 -200.490460251995 367.169770395944 -0.54604293821845 0.585416892635036 PGF other 1 1 1 2.04318553267853 -0.54604293821845 0.0933341752176312 122.149708724413 69.7749097384986 1.75062510553154 0.0809687842642862 -161.068086985375 209.906034516137 -0.76733423770622 0.443448601661969 IFI27L2 other 1 1 1 1.75062510553154 -0.76733423770622 0.984509325499247 -1.33876833418416 7.68600932518325 -0.174182501938643 0.861832523856564 -1.65380148330757 23.6861780840139 -0.069821373352915 0.944379583375984 BBOF1 other 1 1 1 -0.174182501938643 -0.069821373352915 5.37375825482492e-13 308.743309851641 41.2202570066515 7.49008696869166 6.76105392519929e-13 -74.9777981381571 133.791617001729 -0.56040729470508 0.575593785625872 NEK9 other 7.11969231181754e-09 1 9.5060418188302e-09 7.49008696869166 -0.56040729470508 0.609581139950567 -4.93354813340364 8.01774840462924 -0.615328379542957 0.538775230595261 -23.5651584647675 26.0237951353695 -0.905523515774205 0.36586938514444 ACYP1 other 1 1 1 -0.615328379542957 -0.905523515774205 2.16269236412906e-05 71.37599436818 15.4438422574808 4.62164746169992 5.54097009338556e-06 7.79622492080249 50.0244949797669 0.155848148471179 0.876251601830622 IFT43 other 0.200200432147428 1 0.0632723374963697 4.62164746169992 0.155848148471179 0.28663621463034 14.6788750489502 9.91075684972045 1.48110535567869 0.139562450078323 27.4113484156951 30.7455264893873 0.891555668274435 0.373301018972919 DNAL1 other 1 1 1 1.48110535567869 0.891555668274435 0.0729837522808973 96.454694137799 45.9782585231159 2.09783269823727 0.0367039136619795 -66.358311031604 149.912761510014 -0.442646178772254 0.658320729994751 IRF2BPL other 1 1 1 2.09783269823727 -0.442646178772254 1.37731949454413e-08 71.6263765491101 11.9921285647575 5.97278257669836 6.20368073524985e-09 -7.08066050505062 37.2024369119992 -0.190327868085621 0.849172900037421 ACOT2 other 0.000158749844941156 1 8.07347010885416e-05 5.97278257669836 -0.190327868085621 6.37256617993607e-09 1260.30378328102 199.16316197791 6.32799645659779 8.37426998959325e-10 1017.89544910953 650.028241449967 1.56592496172012 0.118354510062254 LTBP2 other 7.46482402317711e-05 1 1.11679264581216e-05 6.32799645659779 1.56592496172012 5.84410976580489e-15 194.342030334753 26.4724677918403 7.34128876321291 1.76237152156751e-12 -220.119967726416 86.4007756990696 -2.54766193874329 0.0113120935678415 AREL1 other 8.0303912291925e-11 1 2.46679141873805e-08 7.34128876321291 -2.54766193874329 7.55769456118279e-08 50.8924646152316 8.94702136587302 5.68820197628596 2.89796163650395e-08 -2.50356273111346 29.068750222111 -0.0861255716872594 0.931420458794381 MLH3 other 0.000838979673236902 1 0.000368562760930573 5.68820197628596 -0.0861255716872594 8.30081856333863e-11 121.621694239118 19.2884345333457 6.30542069284362 9.60185249788644e-10 -103.968497008096 62.4775998352052 -1.66409236722169 0.0970790038117683 TTLL5 other 1.04108866421393e-06 1 1.27858267861856e-05 6.30542069284362 -1.66409236722169 3.24495744338924e-05 90.9966673473557 20.5822904987627 4.42111471280741 1.34806316599764e-05 -19.9460771901162 66.6859282990229 -0.299104739168914 0.765054897525782 FLVCR2 other 0.295258677773987 1 0.149918104690597 4.42111471280741 -0.299104739168914 1.01220051679547e-11 116.294474510922 15.9049055643233 7.31186199381058 2.12673966663191e-12 27.109736370058 51.9103919205279 0.522241026643791 0.601863851297674 ABCD4 other 1.30148742449561e-07 1 2.97296937998474e-08 7.31186199381058 0.522241026643791 5.94794709286396e-27 621.126678381719 55.3422116803585 11.2233801202087 7.18088382198844e-25 -337.608169004252 180.625775265234 -1.86910294784066 0.0625217877340906 DLST other 8.92311022871451e-23 1 1.08165653010612e-20 11.2233801202087 -1.86910294784066 0.167091239261519 21.1455721578404 11.9105459107539 1.77536548839029 0.0767879651063539 -5.20064962694505 35.8308662873023 -0.145144401065962 0.884688239508189 PPP4R4 other 1 1 1 1.77536548839029 -0.145144401065962 0.0520409312461657 105.368110637021 43.1451906500173 2.44217510803788 0.0151433858615178 68.9768676089175 140.386298414332 0.491336180154428 0.623527628625952 TGFB3 other 1 1 1 2.44217510803788 0.491336180154428 0.435231337144106 1.70620349512432 2.37463649391076 0.71851144354073 0.472966282736958 -6.73917613329974 7.70753215489099 -0.874362376681521 0.382576673001111 ZC2HC1C other 1 1 1 0.71851144354073 -0.874362376681521 3.54179149858897e-06 173.105749617402 37.455590523644 4.62162649680102 5.52904725867555e-06 -133.099142144474 120.885846264252 -1.10103164479259 0.271710386113305 SLIRP other 0.0351168627085097 1 0.0631417196940748 4.62162649680102 -1.10103164479259 0.000225229297689077 176.681669974247 50.0317261396139 3.53139265035979 0.000474310089698881 -201.777760554265 154.085114536741 -1.30952143664826 0.19130014135432 RBM25 essential 1 1 1 3.53139265035979 -1.30952143664826 0.843805691170423 3.69887593821574 19.6870561159507 0.18788364885184 0.851087315745014 35.2215769811104 60.6701211751738 0.580542387238927 0.561958785820016 ALDH6A1 other 1 1 1 0.18788364885184 0.580542387238927 4.15717983083693e-05 156.021734135962 55.6151105917256 2.80538386916693 0.00533516027792576 -431.56393490442 165.129463292337 -2.61348838844344 0.00938842683593793 GPR68 other 0.374354043766865 1 1 2.80538386916693 -2.61348838844344 2.25485887660978e-25 208.300921570154 19.9322052089168 10.4504704515569 3.45784427790907e-22 -173.780974342383 65.0546826606876 -2.67130615714153 0.00794212654962848 EIF2B2 essential 3.36672978866607e-21 1 5.17500974631872e-18 10.4504704515569 -2.67130615714153 8.73309468612795e-09 145.871310926356 25.3150353333939 5.76224006821481 1.96109232403349e-08 -52.0904607462355 74.37420314539 -0.700383446722874 0.484199969440897 NRDE2 essential 0.000101679421430588 1 0.000251196315785449 5.76224006821481 -0.700383446722874 1.02637376344439e-07 43.8886876993824 9.41712200642597 4.66052023850111 4.64055376902648e-06 -66.5519633559253 29.0209937883173 -2.29323516077235 0.0224845858577749 COQ6 other 0.00113198762370281 1 0.0532225111769647 4.66052023850111 -2.29323516077235 1.89444169602257e-17 239.659324774373 28.563552610946 8.39038925019894 1.59181974351915e-15 -177.650055889307 88.5828173539428 -2.00546856823808 0.0457572545983035 ZNF410 other 2.68612888079041e-13 1 2.3033631688722e-11 8.39038925019894 -2.00546856823808 6.78838858114428e-09 259.1423207772 41.3232341614066 6.27110452596722 1.16074277672873e-09 26.6808146780315 150.427842858277 0.177366198777233 0.859332969931123 RHOQ other 7.94105696222258e-05 1 1.5421628531618e-05 6.27110452596722 0.177366198777233 0.493515009545704 0.408056983396897 1.24587816335529 0.327525592308282 0.743485226790785 -5.36784407256704 4.93261253863302 -1.08823550005706 0.277312642898904 GPR75 other 1 1 1 0.327525592308282 -1.08823550005706 5.28508738634258e-05 81.2688233194526 21.0283778114385 3.86472147534109 0.000134669976073186 -135.627274241523 74.5783599009222 -1.81858751548981 0.0699090622899672 SUPT7L other 0.47037277738449 1 1 3.86472147534109 -1.81858751548981 0.648214406872468 1.83938542432972 20.8964014214268 0.0880240280244445 0.929912810360596 -62.6864394770799 69.8051587911545 -0.898020154421931 0.369852084357738 KLHL29 other 1 1 1 0.0880240280244445 -0.898020154421931 0.00871790180542101 129.847854852367 41.8822148243718 3.10031012917699 0.00210555657004931 52.9004049210215 140.786947077329 0.375747937001329 0.707354039148383 DNMT3A other 1 1 1 3.10031012917699 0.375747937001329 8.95097406888059e-11 430.363731725092 63.713455286751 6.7546757555085 6.76202556747102e-11 -238.454881168451 221.667414469652 -1.07573267698802 0.282857206763726 TMEM214 other 1.12128852160867e-06 1 9.2152884433495e-07 6.7546757555085 -1.07573267698802 0.000166562222748056 62.5208438308314 16.3297782796028 3.8286400929843 0.000155183841768163 -64.1651970170309 55.2844917907931 -1.16063646311237 0.246660324921013 ATAD2B other 1 1 1 3.8286400929843 -1.16063646311237 8.9309658270897e-10 52.3675517770471 7.95985388766706 6.57895892513618 1.94148961139015e-10 -1.08896802439712 26.7570264066869 -0.0406983948008879 0.967561801082238 FKBP1B other 1.08225443892673e-05 1 2.62295246498809e-06 6.57895892513618 -0.0406983948008879 0.00184255778509256 293.825249497579 85.6374845276581 3.43103549944514 0.000680434407500826 -129.299750640523 293.312876878304 -0.440825346696832 0.659638036110378 ATL2 essential 1 1 1 3.43103549944514 -0.440825346696832 0.558363151150666 7.81253766775116 65.772677212848 0.118780898069101 0.90552347171589 -238.413059380478 228.680974887411 -1.04255747334407 0.297940277408543 YPEL5 other 1 1 1 0.118780898069101 -1.04255747334407 4.84340096563425e-10 180.901588252715 28.059601331672 6.44704770087107 4.19966012587931e-10 -104.547675131378 97.6230099316924 -1.0709327156019 0.285006741563547 FAM98A other 5.93074448241914e-06 1 5.63930361703074e-06 6.44704770087107 -1.0709327156019 1.57513320761767e-09 188.99282324662 30.0107279870633 6.2975087884602 9.97807790364742e-10 -93.9044052317288 104.411233848554 -0.899370707254884 0.369131503430079 YIPF4 other 1.8881121759713e-05 1 1.32818194975451e-05 6.2975087884602 -0.899370707254884 0.00030233184263035 172.909252251202 43.1891964289809 4.00353020078826 7.76695838311657e-05 169.306588349182 177.301731215443 0.954906571913021 0.340347996317322 AFTPH other 1 1 0.814365586469772 4.00353020078826 0.954906571913021 0.778742927735522 66.4478138143985 131.263117370747 0.506218465212278 0.613052955287951 278.463909686756 538.865732147598 0.516759357803223 0.605682223299517 LGALSL other 1 1 1 0.506218465212278 0.516759357803223 0.364402629173455 5.05723300606192 6.01659638497663 0.840547160299762 0.401231243058687 -29.7511196380175 25.9456992126507 -1.14666864030827 0.252377945454084 CNRIP1 other 1 1 1 0.840547160299762 -1.14666864030827 0.229513684587778 77.0210608702073 50.7547098216619 1.51751553975657 0.130123844460528 195.393727507957 207.347851995756 0.94234748818115 0.346725634101393 BCL11A og 1 1 1 1.51751553975657 0.94234748818115 0.000324468384604147 38.5686952507435 12.1068804603491 3.1856839899476 0.00158643781771638 -88.6574595435403 44.0723469097256 -2.01163463622982 0.0450964483003509 CRIPT other 1 1 1 3.1856839899476 -2.01163463622982 0.00327727535003423 683.660291950551 202.63875839347 3.37378839749435 0.000832528212355557 747.878594234673 737.660348305413 1.01385223694446 0.311419219721177 EPCAM other 1 1 1 3.37378839749435 1.01385223694446 0.00319136253990308 17.9907685206555 20.8246281623659 0.863917875526259 0.388288277291468 -155.027112453466 50.5048897554315 -3.06954659646186 0.00232971295023264 SLC17A5 other 1 1 1 0.863917875526259 -3.06954659646186 0.332501898062963 -147.435999529913 105.659185272093 -1.39539216728045 0.163877422494785 -193.359895652875 252.661318171369 -0.765292831733459 0.444668377485038 OGFRL1 other 1 1 1 -1.39539216728045 -0.765292831733459 0.0272374484901763 -13.777908977787 33.6653185579004 -0.409261209101308 0.682621770551579 -158.07691350507 61.6600236522811 -2.56368558008528 0.0108132213483891 SLF2 other 1 1 1 -0.409261209101308 -2.56368558008528 9.93989016102345e-05 134.323441332058 56.3085085021374 2.38549101912296 0.0176396656491343 -232.733779839412 108.182263955405 -2.15131178929062 0.0322021477945747 IDE other 0.857216127486662 1 1 2.38549101912296 -2.15131178929062 0.512076967021648 0.918627111540359 9.31819728028909 0.0985842093602744 0.921530325739634 -16.9901197222881 17.1222396057731 -0.992283726514346 0.321811205889264 ELOVL3 other 1 1 1 0.0985842093602744 -0.992283726514346 0.0136477286227848 -119.895693221024 332.423173900627 -0.360671886421689 0.718583456167635 -1868.36033374076 666.144253376739 -2.80473834949395 0.00534460800930197 IFIT3 other 1 1 1 -0.360671886421689 -2.80473834949395 0.162915150545012 -26.8564834498478 16.0664469673104 -1.67158821763713 0.0955830840541084 -46.7354275717384 29.3845646482412 -1.59047541221734 0.112715085778742 NKX2-3 other 1 1 1 -1.67158821763713 -1.59047541221734 0.0701693169528383 -52.7745993248234 118.004055562025 -0.447226996338987 0.655015632504741 -533.403780466491 237.073398063633 -2.24995206051469 0.0251354081584678 IFIT2 other 1 1 1 -0.447226996338987 -2.24995206051469 0.0474532062244779 6.79551338775967 20.3559465180896 0.333834311350777 0.73872324749477 -79.9835793199594 38.414822430719 -2.08210201841254 0.0381273661251946 GPAM other 1 1 1 0.333834311350777 -2.08210201841254 5.2151338794409e-06 44.233832323852 19.5664693085794 2.26069566390584 0.0244495596028538 -105.436805182857 35.7858948842643 -2.94632300027292 0.00345177182051852 CUTC other 0.0510092244748115 1 1 2.26069566390584 -2.94632300027292 0.761768056721757 18.5094930343397 53.131766542548 0.348369614616845 0.727792410510218 -43.6177196997126 103.035344722313 -0.423327740759883 0.672341419144535 PPP1R3C other 1 1 1 0.348369614616845 -0.423327740759883 0.474424334737459 4.92436197708099 13.4639878385293 0.365743198533584 0.714799119385761 29.5397541853005 24.5618989448226 1.20266573246883 0.229997593630012 CNNM1 other 1 1 1 0.365743198533584 1.20266573246883 0.00493126136791683 126.865261886307 58.3039361598397 2.17592962400526 0.0302917943590749 -143.290445702162 110.028553700603 -1.30230236500306 0.193749578668924 MXI1 other 1 1 1 2.17592962400526 -1.30230236500306 1.16709483504635e-07 119.704288950697 32.5314110826687 3.67965252556997 0.000273951233996044 -152.439448742352 61.3918089758631 -2.48305842889049 0.013537982476165 SMNDC1 essential 0.00128298735216646 1 1 3.67965252556997 -2.48305842889049 0.0034440344165523 12.2885527914471 6.50937316364925 1.88782429313946 0.0599541436665042 -22.6548819901959 12.9558578053118 -1.74862076526554 0.081315471145869 C10orf88 other 1 1 1 1.88782429313946 -1.74862076526554 0.0791132178210521 -70.4890045820658 55.4794788897134 -1.27054193717626 0.204820394317528 -229.471475952713 102.091513830776 -2.24770372523889 0.0252801225474625 HELLS other 1 1 1 -1.27054193717626 -2.24770372523889 6.87803328090148e-08 80.039429967193 31.2621533788583 2.56026605068483 0.0109180032448056 -201.969817748076 57.2560445652741 -3.52748463994615 0.000480897068867218 TCTN3 other 0.000764837300836244 1 1 2.56026605068483 -3.52748463994615 1.85350921648088e-07 33.2231314018529 13.9011906411496 2.38994862091219 0.0174290150222776 -99.1118558381722 27.0608005409944 -3.66256185540511 0.000292102719360124 FAM45A other 0.00201513522015802 1 1 2.38994862091219 -3.66256185540511 0.000197387273734417 -21.8570583727493 74.7497602787435 -0.292403056427792 0.770167964914972 -525.591231054501 136.90277678241 -3.83915683383007 0.000148798761900277 AVPI1 other 1 1 1 -0.292403056427792 -3.83915683383007 0.00149846450635536 19.273570560545 48.7871641016549 0.395054127769875 0.693066142465543 -297.175959297367 95.7534711572298 -3.10355286033857 0.00208274696538874 WDR11 other 1 1 1 0.395054127769875 -3.10355286033857 8.22840883751937e-13 87.2250256104096 26.0270774753824 3.35131847564949 0.000901215960497458 -228.935421062273 47.6920651085555 -4.80028324504665 2.44222384439602e-06 C10orf76 other 1.08606768246418e-08 0.0363989041768782 1 3.35131847564949 -4.80028324504665 0.269966680708238 -3.20468223237681 5.50240479430823 -0.582414844449791 0.560697417811123 -16.2918731612223 10.0931459682758 -1.61415213972234 0.107480024620771 KCNIP2 other 1 1 1 -0.582414844449791 -1.61415213972234 0.645363566788869 -0.422008828801071 4.56319058549616 -0.0924810877157753 0.926373686586673 -7.50684101804112 8.53524743206871 -0.879510650134915 0.379784442145302 CFAP58 other 1 1 1 -0.0924810877157753 -0.879510650134915 0.017748465692593 -30.4292680504349 110.973554071477 -0.274202879280913 0.784105636499082 -538.134260453188 202.963952172699 -2.65137850683602 0.00841540948540734 GOT1 other 1 1 1 -0.274202879280913 -2.65137850683602 0.0303010165413329 -1.92677600878895 3.76975084811404 -0.511114948021802 0.60962302640418 -17.7858075206399 6.9258390872877 -2.56803649297679 0.0106811986293474 C10orf95 other 1 1 1 -0.511114948021802 -2.56803649297679 0.97947868900261 -2.18571105926834 13.0149924225548 -0.167937943281514 0.866738186036952 -4.2838740925155 23.8367132657742 -0.1797174822196 0.857488114543817 SFRP5 other 1 1 1 -0.167937943281514 -0.1797174822196 0.000116970076905002 283.417475008844 73.6974220873362 3.84569048660855 0.000145226563814063 -253.701106748057 171.060511361325 -1.48310737954111 0.139036257830181 GNA13 other 1 1 1 3.84569048660855 -1.48310737954111 0.00817883851222576 105.330850562234 40.0977727930063 2.62685040154165 0.00903796322944787 -149.96241637766 100.459995483778 -1.49275754647905 0.136498376332782 KANSL1 essential 1 1 1 2.62685040154165 -1.49275754647905 0.950370824537665 -0.453242013870874 1.92951761090904 -0.234899132979326 0.814437730697436 -1.0598154009351 4.60231209053491 -0.230278907663544 0.81802265106628 HOXB5 other 1 1 1 -0.234899132979326 -0.230278907663544 0.512293875418075 -24.379982600822 22.4089646811074 -1.08795667036667 0.277435533325365 -25.4141821907064 53.2734189235951 -0.47705183380769 0.633651859371969 HOXB3 other 1 1 1 -1.08795667036667 -0.47705183380769 0.000187016405122668 1284.92355969431 741.94616420868 1.73182856341705 0.0842677730589893 -3357.38548911261 1123.86694006257 -2.98735141094701 0.00303154965963602 DUSP1 other 1 1 1 1.73182856341705 -2.98735141094701 6.68478433287305e-05 249.962224230271 94.5594393978179 2.64344020884751 0.0086108980046854 -328.662128970481 137.614587733457 -2.38827971934968 0.0175069387052154 PANK3 other 0.587325151486227 1 1 2.64344020884751 -2.38827971934968 0.00869825372168626 50.2592752687487 16.6010473127114 3.02747617797976 0.00266643301776963 42.1048968381833 25.0862815350306 1.67840326512273 0.0942446400563063 MSX2 other 1 1 1 3.02747617797976 1.67840326512273 0.0479116367415733 -14.9814907949048 7.49585966844723 -1.99863544110455 0.0465264538895904 15.0677506601389 16.6453519856451 0.905222711609423 0.366054958831783 TEK other 1 1 1 -1.99863544110455 0.905222711609423 1.18282535357668e-50 168.112015627625 9.92155989694159 16.94411134679 3.42833391877276e-46 -140.850326555761 33.3858396949154 -4.21886428027185 3.21677680822472e-05 RCL1 other 1.81303470196234e-46 0.466979489249982 5.25049339660048e-42 16.94411134679 -4.21886428027185 3.74178272110013e-25 93.3057312441337 10.7423348911231 8.68579616906533 2.27346145322813e-16 -125.750579570367 23.8430587725708 -5.27409594422636 2.52297318749741e-07 CAAP1 other 5.58124310679295e-21 0.0038031297828336 3.3085684528829e-12 8.68579616906533 -5.27409594422636 3.77236026340048e-16 338.967697832083 44.3874740616241 7.63656200308868 2.83165163790465e-13 -246.198461692181 99.8144520063288 -2.46656127187445 0.0141859036458566 MOB3B other 5.26772387181243e-12 1 4.00282275534202e-09 7.63656200308868 -2.46656127187445 1.51737910248174e-06 134.195204993906 35.0856369940872 3.8247903270652 0.000157972914094574 -348.591456076593 118.12711717523 -2.95098589055967 0.00340679282948331 CD274 other 0.015493958015441 1 1 3.8247903270652 -2.95098589055967 0.0529506789569723 27.1005712032011 30.3448031595194 0.893087724469206 0.372481328893855 -132.610191653927 66.5113032708466 -1.99379932631772 0.0470224482551628 NUP43 essential 1 1 1 0.893087724469206 -1.99379932631772 4.42922661748568e-05 213.408380331174 54.8129868294876 3.89339083080886 0.000120338317242356 -165.031671008995 120.794356643442 -1.36622004201845 0.172829206924681 MTHFD1L other 0.397567381185515 1 1 3.89339083080886 -1.36622004201845 3.62604094337836e-05 250.048675142296 73.5023672173021 3.40191322550269 0.000754091286637777 -355.632956183034 161.106276136165 -2.20744321520073 0.0279923806251037 LRP11 other 0.32833800742291 1 1 3.40191322550269 -2.20744321520073 0.357959428968128 -21.8976230970673 17.4179435853082 -1.25718762320127 0.209602492081319 -37.2572719944054 38.3848684616323 -0.970623933012718 0.332468653833106 CCDC170 other 1 1 1 -1.25718762320127 -0.970623933012718 1.25412389357995e-09 245.709668317858 48.6164344726983 5.05404542687807 7.28974172707826e-07 -315.842851532675 106.560006343178 -2.96399054740573 0.00326468186068525 PCMT1 other 1.50933810592347e-05 1 0.00873894238242142 5.05404542687807 -2.96399054740573 0.00308187934334739 -79.687786347454 42.0056400535022 -1.89707349408214 0.0587183990000571 -298.691172862482 92.5701108287192 -3.2266481069159 0.00138210266386752 PLEKHG1 other 1 1 1 -1.89707349408214 -3.2266481069159 0.0573722293177142 -3.54257907542579 5.92859326362315 -0.597541257748691 0.550568670972448 -31.4719184685304 13.1080507957505 -2.40096097878513 0.0169224480587689 MYCT1 other 1 1 1 -0.597541257748691 -2.40096097878513 0.717426430141914 12.7494882493874 42.562737190313 0.299545778561656 0.764718114732621 50.9260058685759 62.4962130826959 0.814865467147424 0.415755351173932 CYSTM1 other 1 1 1 0.299545778561656 0.814865467147424 7.75210621662789e-22 188.710329752099 27.128279272158 6.95622187676956 1.97801089857275e-11 -212.153019368766 40.1597581380051 -5.28272652040689 2.35753970609823e-07 WDR55 essential 1.13839679791181e-17 0.00355564138473735 2.72095179207668e-07 6.95622187676956 -5.28272652040689 0.0781398079653212 21.3668509407423 32.6034284877968 0.655355952786983 0.512710926459661 -84.8005289768007 46.4876896187549 -1.82415021422336 0.0690647679546523 ARAP3 other 1 1 1 0.655355952786983 -1.82415021422336 0.0646990373432649 17.8942750207703 8.03239936765624 2.22776211711092 0.0265956896257262 18.163836993122 12.7012591906088 1.43008159431563 0.153675371990582 PCDHB8 other 1 1 1 2.22776211711092 1.43008159431563 0.543555978090071 12.0983835322658 11.0231462248681 1.09754359467463 0.273234199363302 8.34730313789579 17.4303879687302 0.478893708669635 0.632343367822646 PCDHB10 other 1 1 1 1.09754359467463 0.478893708669635 0.0159334170593543 46.8495942137632 26.4632293324155 1.7703657261654 0.0776242890808367 -66.7324732987001 41.8450726099301 -1.59475104561927 0.111761266027803 PCDHB14 other 1 1 1 1.7703657261654 -1.59475104561927 0.355620415635016 7.91294167626961 5.67254984192087 1.3949532215287 0.164003483955552 7.09740358694423 8.96973899280945 0.791260882020517 0.429381534794001 PCDHB12 other 1 1 1 1.3949532215287 0.791260882020517 0.241191298005366 3.61269756585527 4.91609021939733 0.734872104584394 0.462957267794375 -24.0275725241746 15.5359355742292 -1.54658034010074 0.122955933036409 TNN other 1 1 1 0.734872104584394 -1.54658034010074 0.000209447994367558 52.260126708903 12.9747608526944 4.02782966886442 7.04148880845075e-05 38.7625032153569 41.0031223396064 0.945354914543051 0.345193201446228 MRPS14 essential 1 1 0.741398356641779 4.02782966886442 0.945354914543051 0.104331986017688 21.4212152695267 11.1295831573592 1.92470957507176 0.0551576208468476 31.067994635808 35.8300203514685 0.867093971230041 0.386544326531489 CENPL other 1 1 1 1.92470957507176 0.867093971230041 0.391107356032291 13.6648580004618 15.1566499986579 0.901575084314268 0.367962819559674 -51.7532352585457 48.8328033867492 -1.0598047146437 0.290035228679644 TNFSF18 other 1 1 1 0.901575084314268 -1.0598047146437 0.790651062321711 -1.04115988723312 18.1171009201194 -0.0574683494795181 0.954208097922561 -38.8525228698004 57.0709568867737 -0.680775739346409 0.496507238018281 SEC16B other 1 1 1 -0.0574683494795181 -0.680775739346409 0.0145511161673472 30.5668476883729 10.7489567192608 2.84370367159456 0.00474613208914234 -27.0393471551518 34.6586940390189 -0.780160588991347 0.43587302865935 GORAB other 1 1 1 2.84370367159456 -0.780160588991347 0.225840313939202 50.2546197803285 77.6652906074362 0.647066654708644 0.518052685709063 -240.361089121973 171.360751634977 -1.40266126769785 0.161687295252958 ACAT2 other 1 1 1 0.647066654708644 -1.40266126769785 6.64926236757012e-09 666.701839666204 166.349789515328 4.00783097837807 7.62851277137878e-05 -1391.38601930646 367.034292187887 -3.79088834182884 0.0001793797575024 TCP1 essential 7.78163174876732e-05 1 0.800459845100776 4.00783097837807 -3.79088834182884 1.29148740821089e-21 358.977530248043 63.7461666658321 5.63135870004329 3.9618927702071e-08 -394.649235132081 116.588791062429 -3.38496721284947 0.000801940913174235 SNX19 other 1.89461202784538e-17 1 0.000500941721864986 5.63135870004329 -3.38496721284947 0.224373886455279 28.9734365491282 16.7689848118524 1.7277990811137 0.0849981576334474 36.7307249010837 30.6381574833949 1.19885554217778 0.231479534993178 KCNJ5 other 1 1 1 1.7277990811137 1.19885554217778 1.70490029457076e-05 21.1971017199873 6.90611940622672 3.069321636819 0.0023296284461811 -11.3805924881712 12.7884471506002 -0.889911992765831 0.374183769090269 MSANTD2 other 0.159408177542366 1 1 3.069321636819 -0.889911992765831 7.65692124194413e-07 91.475736570233 33.5681319443129 2.72507676989547 0.00678564293720221 -116.52859812433 61.3314237249659 -1.89998195128961 0.0583427446099003 TP53AIP1 other 0.00799229439234128 1 1 2.72507676989547 -1.89998195128961 9.19243354026445e-07 30.8080837438453 10.3255927172846 2.98366249641765 0.00307086586283107 -54.4909305649303 17.8713153591227 -3.04907218466796 0.00249018209076598 SLC10A7 other 0.00954818071827268 1 1 2.98366249641765 -3.04907218466796 2.61615687896428e-15 146.687918173904 16.982078010518 8.63780734507583 2.76632402396056e-16 68.2943781156852 93.105361161526 0.733517138687676 0.463780119740239 NUDCD1 other 3.61369749691336e-11 1 4.02251176324106e-12 8.63780734507583 0.733517138687676 8.24577830395534e-12 197.268634507774 26.9522727414803 7.31918366958985 2.02968215449324e-12 -145.679270327646 147.767610428196 -0.985867402913946 0.324943005526591 ENY2 other 1.06296328116288e-07 1 2.83810455662789e-08 7.31918366958985 -0.985867402913946 3.30404623865712e-08 69.7458000245755 27.9729636615603 2.49332894677936 0.0131647888340995 -199.719160205772 55.1170090851786 -3.6235485836527 0.000338335981032753 MASTL essential 0.000374018034215986 1 1 2.49332894677936 -3.6235485836527 2.19390894104835e-10 492.06174948762 151.065674488217 3.25727039682996 0.00124637278056054 -1097.89677682011 301.260298463197 -3.64434604367304 0.000312987036484468 KIAA1217 other 2.71956952332354e-06 1 1 3.25727039682996 -3.64434604367304 0.194917757326953 219.332312106086 121.063378902263 1.81171477365718 0.070967622320918 238.587493544992 241.378070385251 0.988438979415966 0.323684492498344 PLXDC2 other 1 1 1 1.81171477365718 0.988438979415966 6.59587750847297e-08 41.8784401714193 19.3467600324828 2.16462291883014 0.0311674163389756 -155.423711548386 41.139556820002 -3.77796270942859 0.000189037519204993 EPC1 other 0.000734319043018295 1 1 2.16462291883014 -3.77796270942859 0.113208953294088 8.86891308821546 5.18618248165094 1.71010432424896 0.0882602226664387 36.4853817598697 24.9052614945597 1.46496682108074 0.143956637160648 IQSEC3 other 1 1 1 1.71010432424896 1.46496682108074 7.7832939050487e-11 62.1281000096863 8.99616244439161 6.90606693617657 2.8878387001995e-11 -21.4494799894795 43.2016765545409 -0.496496471899652 0.61990064509683 CCDC77 other 9.77192549778864e-07 1 3.96240348054373e-07 6.90606693617657 -0.496496471899652 2.37764740372879e-06 50.4227970170548 19.8583941306015 2.53911754824898 0.0115879128897354 -151.135446015868 39.7919330873707 -3.79814284679312 0.000174527452448802 TAF12 other 0.0238929787600706 1 1 2.53911754824898 -3.79814284679312 0.886657017130511 1.62085779891805 3.33626926737883 0.485829430725624 0.627423743392498 1.6330124754434 6.20113957252234 0.263340706388773 0.792459074841422 ENOX1 other 1 1 1 0.485829430725624 0.263340706388773 0.724937215523641 -4.17832432432435 5.77034422201789 -0.724103132076788 0.469533118686195 -6.59075910693303 10.7148550955898 -0.615104828589398 0.538924028551659 TNFSF11 other 1 1 1 -0.724103132076788 -0.615104828589398 2.17527908392548e-12 25.4368810685974 5.67519608683847 4.482114922441 1.03275304981777e-05 -38.6178366752295 10.5287473449303 -3.66784721962432 0.000286648381316268 MTRF1 other 2.84352481850739e-08 1 0.115709651701583 4.482114922441 -3.66784721962432 0.0123014136079281 35.0168236079779 12.8059276900563 2.73442303091936 0.00659923735138106 51.994981566147 22.4917541170377 2.31173528287687 0.0214310209432756 SOHLH2 other 1 1 1 2.73442303091936 2.31173528287687 5.25980786835932e-08 82.8102527060187 34.5221001698194 2.39876057072608 0.0170262342782485 -253.650116735517 64.2027132979198 -3.95076942556158 9.600118837385e-05 DNAJC15 other 0.000588730294705459 1 1 2.39876057072608 -3.95076942556158 2.37753115220952e-12 188.905874160402 37.749325838393 5.00421848509612 9.30201831589939e-07 -196.598951607229 68.1268927660498 -2.88577599278388 0.00417143493749394 PROSER1 other 3.10481793167041e-08 1 0.0111066098691839 5.00421848509612 -2.88577599278388 7.02630904611345e-18 292.274778756075 46.6902174293318 6.25987187141393 1.24615481321392e-09 -292.285378547887 84.1662048115378 -3.47271662304797 0.000586555444887839 UFM1 other 1.00075719743794e-13 1 1.65451974550412e-05 6.25987187141393 -3.47271662304797 1.68323479903987e-28 62.4983238127688 9.94601091644357 6.28375781384287 1.08711581862301e-09 -123.177484164776 17.9195001045241 -6.87393529095589 3.3086848023576e-11 WBP4 other 2.53478328387415e-24 5.06460382696878e-07 1.44564661560488e-05 6.28375781384287 -6.87393529095589 6.66546978505005e-12 231.053867411571 67.5581707716811 3.4200728760469 0.00070769874277511 -535.246058381832 121.718009197347 -4.39742698645368 1.49581667411354e-05 ELF1 other 8.61245350926317e-08 0.219256808091562 1 3.4200728760469 -4.39742698645368 0.962836837785986 -1.09489976962604 6.94437052717696 -0.157667245049947 0.87481907815853 -3.32477446684067 12.1967793490001 -0.27259445888994 0.785341893804519 SMAD9 other 1 1 1 -0.157667245049947 -0.27259445888994 6.74343189785314e-13 1465.54171560454 264.970285046921 5.53096629437156 6.64054643448466e-08 -1290.55497368568 461.419414001804 -2.79692387126266 0.00547236784006989 HSPH1 other 8.91481696896185e-09 1 0.000832591711955686 5.53096629437156 -2.79692387126266 8.97403620232358e-06 45.3331813453491 12.5973137472054 3.59863874593151 0.000370858648561082 -34.3158433332688 23.3708107419828 -1.46832062062891 0.143005592358837 KBTBD7 other 0.0860340850716762 1 1 3.59863874593151 -1.46832062062891 1.24273723966738e-10 86.3524817538437 19.2332292851345 4.48975470908497 9.98532930838402e-06 -92.8794836940414 33.7803769026241 -2.74950998805541 0.00630979836888368 ALG5 other 1.54857487434952e-06 1 0.112065350827994 4.48975470908497 -2.74950998805541 8.12949649433116e-10 47.0865166141773 18.9343862793521 2.48682560498542 0.0134014534545949 -146.403846412215 33.2555025187969 -4.4023946512149 1.46389264031042e-05 EXOSC8 essential 9.87002169376747e-06 0.214650577848718 1 2.48682560498542 -4.4023946512149 3.20702810376336e-16 631.445395859697 109.014319050971 5.79231610449684 1.65976758043946e-08 -718.120106065089 160.06917229057 -4.48631111030861 1.01177811000133e-05 ETF1 essential 4.48214247781967e-12 0.148933737792195 0.000213064364301013 5.79231610449684 -4.48631111030861 0.000228452354302892 12100.3036791497 2945.39692406599 4.10820816042875 5.07360092593584e-05 8852.80566526233 4361.56347820611 2.02973216129906 0.043213458343299 TGFBI other 1 1 0.54089659471402 4.10820816042875 2.02973216129906 1.49502623449826e-06 108.477056020676 42.7132131603227 2.53966040001512 0.0115688139455687 -221.173077233692 62.7171617083329 -3.52651604774879 0.000482592926272234 FAM53C other 0.0152716929853997 1 1 2.53966040001512 -3.52651604774879 0.0271349452657523 94.357052790266 69.5942793653306 1.35581622010834 0.176113671723734 -178.784759469135 102.187481343241 -1.74957594725923 0.0811501044800924 SIL1 other 1 1 1 1.35581622010834 -1.74957594725923 1.36109429879964e-12 275.644567259808 58.2663812957371 4.73076517075507 3.36093232414002e-06 -356.836599456213 85.5543703576647 -4.17087517521826 3.9122755863774e-05 PAIP2 other 1.78820568976297e-08 0.566458382151584 0.0388994307195965 4.73076517075507 -4.17087517521826 0.218590073670147 50.5476945141773 167.826304698894 0.301190535088451 0.763464821649285 430.15745939548 249.903117787866 1.7212968897836 0.086163453387938 MYOT other 1 1 1 0.301190535088451 1.7212968897836 1.96743022939346e-06 228.032498452098 92.9645655783056 2.45289694017903 0.014704377376592 -483.061431071147 136.502811685813 -3.53883868841474 0.00046142985750796 KDM3B other 0.0198907196191678 1 1 2.45289694017903 -3.53883868841474 0.208604162364881 1134.81710124641 759.788668611538 1.49359571697773 0.136266653633294 -452.04952593749 1115.62173078877 -0.405199642012962 0.685601521796811 EGR1 other 1 1 1 1.49359571697773 -0.405199642012962 2.37050382441833e-17 750.701803273606 80.8990790414341 9.2794851581576 2.715863074489e-18 -30.526215021075 490.898035752214 -0.0621844309771967 0.950455026797057 SERP1 other 3.35639636499391e-13 1 3.99802203195526e-14 9.2794851581576 -0.0621844309771967 0.00020015332618547 90.139227007082 22.0686367485618 4.08449457182517 5.59576929565601e-05 148.031092330515 113.04298339559 1.30951154935893 0.191306445316155 PLS1 other 1 1 0.593823037655016 4.08449457182517 1.30951154935893 0.0473665615243786 16.4874741812456 8.14529767042774 2.02417085886314 0.0437830390177415 -19.591332787041 23.812187517014 -0.822743931990408 0.411266291446572 ZFP30 other 1 1 1 2.02417085886314 -0.822743931990408 0.00907960519214969 31.4411168566656 12.6068574747192 2.49396940670704 0.0131367173753067 -42.1169084277804 30.681737885057 -1.37270283011878 0.170806002413185 NR2C1 other 1 1 1 2.49396940670704 -1.37270283011878 0.00406082913051007 134.910632584695 43.6709349856172 3.08925450369055 0.00218311365391555 -96.9402185956174 111.800966356704 -0.867078539252757 0.386550720383813 UTP20 essential 1 1 1 3.08925450369055 -0.867078539252757 0.76867567672859 -96.7473091806117 203.372756343826 -0.475714205382794 0.634602583179935 -307.068616194636 498.957007886392 -0.615420990869322 0.538714160858044 TMPO other 1 1 1 -0.475714205382794 -0.615420990869322 0.051245117332221 100.923719644929 56.8985405856506 1.77374882740632 0.0770586339598928 -209.472981216679 145.664658287187 -1.4380494464463 0.151400302127649 ARL1 other 1 1 1 1.77374882740632 -1.4380494464463 0.122791483387922 40.3342690158056 22.8020329008957 1.76888916839608 0.0778649203304304 75.0640963360643 57.8636431080282 1.29725838720393 0.195476772196938 GLT8D2 other 1 1 1 1.76888916839608 1.29725838720393 0.476941108771699 4.83216693960642 7.94194043191109 0.608436562957656 0.543329593068573 24.5551031798742 21.6735175127957 1.13295422237656 0.258081624012729 MTERF2 other 1 1 1 0.608436562957656 1.13295422237656 0.479339737217699 -1.29142581944589 41.066647192807 -0.0314470722039389 0.97493266737543 -120.012963376416 99.9051230574092 -1.20126936140655 0.230537861751896 SOCS2 other 1 1 1 -0.0314470722039389 -1.20126936140655 0.542982183881476 28.1921262445163 26.1460631505501 1.07825511176137 0.281732037359195 26.8635739898635 66.3496309034782 0.404879026816942 0.685836949847211 NFYB essential 1 1 1 1.07825511176137 0.404879026816942 0.0194890977577577 28.7715988110198 15.3254095874052 1.87737878370736 0.0613814221423676 -73.670504507226 39.8176269546717 -1.8501982700047 0.065212437990415 WASHC3 other 1 1 1 1.87737878370736 -1.8501982700047 0.0226850266108607 26.9837477460951 19.7464622078075 1.36651048993607 0.172741183008199 -104.777761953843 48.4253574464861 -2.16369620130592 0.0312297119775783 APAF1 other 1 1 1 1.36651048993607 -2.16369620130592 0.0710897137345805 -67.8285600318793 92.1132248869304 -0.736360713840377 0.462050665017091 -384.75686336176 175.893737283722 -2.18743924203017 0.029433749776553 DUSP4 other 1 1 1 -0.736360713840377 -2.18743924203017 1.03827705381167e-17 380.705678265787 111.912948304106 3.40180188293565 0.000754663922394444 -970.075718872226 206.88152086201 -4.68903996272952 4.0747440454123e-06 TNFRSF10B other 1.47653379822557e-13 0.0605140238184181 1 3.40180188293565 -4.68903996272952 1.40130760589349e-18 604.289053120593 100.40639433621 6.01843196457326 4.81923701448e-09 -390.076822752304 185.672103731744 -2.10089084419424 0.0364325307176788 SORBS3 other 2.00877445304832e-14 1 6.29199584610509e-05 6.01843196457326 -2.10089084419424 5.92276784197594e-10 394.330613480403 96.1193680089156 4.10250942810846 5.19001585380341e-05 -287.754546287607 176.692859083418 -1.62855787030848 0.104390706892528 PTK2B other 7.22399993685805e-06 1 0.552944289064216 4.10250942810846 -1.62855787030848 1.05201072891024e-18 36.3263484695341 14.1425267930621 2.56858968705329 0.0106645162863829 -148.137530025623 26.1524449623964 -5.66438549965881 3.28844838130467e-08 PPP3CC other 1.5095301949133e-14 0.000498430121154348 1 2.56858968705329 -5.66438549965881 1.19979243112559e-08 129.554005121056 57.0837628609582 2.26954213646738 0.0239004881417995 -323.596750921153 105.559635015156 -3.0655349544804 0.00235787149334475 PDLIM2 other 0.000138696005038118 1 1 2.26954213646738 -3.0655349544804 8.20980898319699e-10 101.942963374251 48.5590355334749 2.09936137022274 0.0365705023285019 -326.465757509942 89.4058368824776 -3.65150384911754 0.000304588043050981 EPHX2 other 9.96260320110955e-06 1 1 2.09936137022274 -3.65150384911754 5.30989856034905e-08 71.4253927037825 15.801477423625 4.52017180349185 8.7186444811916e-06 -74.5922273403642 33.0843039735198 -2.25461074834963 0.0248357025784506 UBIAD1 other 0.000594230747888662 1 0.0983375911033601 4.52017180349185 -2.25461074834963 0.0191146187333963 33.1284827266106 77.4255279744603 0.427875451330967 0.669029611916762 -411.417609649185 163.037164303285 -2.52345906166435 0.0121045747365259 TARDBP other 1 1 1 0.427875451330967 -2.52345906166435 0.411407035410842 8.23309126682553 7.82050416824026 1.05275709720363 0.293246616869506 -7.40007726147949 16.467860877003 -0.449364815306008 0.653472707637152 TNFRSF8 other 1 1 1 1.05275709720363 -0.449364815306008 5.67221770108198e-19 367.172630652515 37.4870807108858 9.79464454659154 5.5344280064416e-20 -14.1771182499662 226.786659985387 -0.0625130166425119 0.950193324319628 ZNF706 other 8.16232127185697e-15 1 8.21917903236643e-16 9.79464454659154 -0.0625130166425119 0.000212244014609298 238.102046606429 59.8071062930956 3.98116647609678 8.57210909800956e-05 -177.359149127409 278.022190523726 -0.637931629821732 0.523995267430783 LYPLA1 other 1 1 0.895114560246206 3.98116647609678 -0.637931629821732 0.0677610321754654 40.5710158150852 17.6580921278843 2.29758773038784 0.0222384041101228 53.0439476885643 83.8234052013245 0.632805927666204 0.527318032551902 CRISPLD1 other 1 1 1 2.29758773038784 0.632805927666204 2.78203765913569e-17 238.062107578296 27.188435525419 8.75600610986707 1.21852988930718e-16 -226.878501740051 126.959981966822 -1.78700798649561 0.074888564658757 COPS5 essential 3.93435765754969e-13 1 1.77612916665415e-12 8.75600610986707 -1.78700798649561 0.222203805334916 180.435844580881 105.625292136551 1.70826362636342 0.0885663544591908 249.637297852215 488.587152385443 0.510937090002068 0.609750756776545 RDH10 other 1 1 1 1.70826362636342 0.510937090002068 0.00141334192137994 212.646329360873 64.8760439552143 3.27773267907131 0.00116334453826271 -189.252324101954 154.259930354228 -1.22684046120968 0.220798742500289 AKAP1 other 1 1 1 3.27773267907131 -1.22684046120968 8.78458122149581e-05 61.4176703846645 15.9671651056842 3.84649810897241 0.000145023646851035 -62.0622375842909 37.9661524808394 -1.63467282115595 0.103116562439796 COIL other 0.761183962842612 1 1 3.84649810897241 -1.63467282115595 0.197886793140836 17.3856440052597 218.764863307733 0.0794718299016949 0.936707800058598 -926.171799058483 520.171245353668 -1.78051325853041 0.0759557258929434 SCPEP1 other 1 1 1 0.0794718299016949 -1.78051325853041 0.013063466205036 84.0737346880644 29.3457893850294 2.86493348619731 0.00444855662722904 -41.0895926312789 69.9928341390019 -0.587054276866075 0.557583805571696 SPOP other 1 1 1 2.86493348619731 -0.587054276866075 0.400897884612264 -31.3197513301705 47.0871096182901 -0.665144910869725 0.506450760368574 118.799487675352 108.122069523294 1.09875336459184 0.272725527752313 TBX2 other 1 1 1 -0.665144910869725 1.09875336459184 3.42598441501735e-06 143.734308791228 28.3989613376931 5.06125231419834 7.05018925075825e-07 72.6039920556684 67.7375953368585 1.0718418877229 0.28460127311497 SLC35B1 essential 0.0340200252411223 1 0.00845670200628452 5.06125231419834 1.0718418877229 0.994989769611956 0.876017255971524 8.74049225842205 0.100225162390302 0.920230147128415 0.212117258154672 20.0493097577982 0.0105797785917378 0.991565498845933 TBX4 other 1 1 1 0.100225162390302 0.0105797785917378 0.345263892477685 -3.45920891056574 25.3785906642864 -0.136304216271302 0.891666768609029 -88.3867762615523 60.5333654352885 -1.46013319474265 0.145237592715715 FAM117A other 1 1 1 -0.136304216271302 -1.46013319474265 6.53036146367721e-07 131.039243140402 30.7004897754605 4.26831116046702 2.63255433056445e-05 -279.9185469247 102.006676106524 -2.74411987145218 0.00642673994163224 NCAPH essential 0.00684773703081192 1 0.286922096488219 4.26831116046702 -2.74411987145218 0.47302903696734 21.3992493995354 34.1517117001599 0.626593758679313 0.531373699253457 -39.88758266487 58.410969725167 -0.682878282153978 0.495179377036285 LRAT other 1 1 1 0.626593758679313 -0.682878282153978 0.0348949953188617 -5.12950215891676 9.684001257431 -0.529688299552899 0.596696505160067 -41.9198813748185 16.5629151836519 -2.53094826061747 0.0118557410204712 MND1 other 1 1 1 -0.529688299552899 -2.53094826061747 0.00466696148681208 20.010617152723 12.3626827369529 1.6186306466403 0.106511908954886 -41.9497318575 24.5937535106302 -1.70570676978477 0.089033037857497 TRIM6 other 1 1 1 1.6186306466403 -1.70570676978477 1.65911289022801e-08 10.4753702715074 2.50089536394027 4.18864796286518 3.66221364834729e-05 -14.3450812108034 6.73260067075354 -2.13068944859874 0.0339015565173192 ABCC11 other 0.000190665253345003 1 0.395189474793156 4.18864796286518 -2.13068944859874 7.61004469553605e-18 98.0772252073598 15.0200159472756 6.52976838051558 2.65931570423911e-10 -121.308757275751 39.7990961307846 -3.04802794709498 0.0024998739965426 PAPD5 other 1.08344206330347e-13 1 3.58316197989177e-06 6.52976838051558 -3.04802794709498 5.06528535523864e-10 220.360002603996 53.2668916791411 4.13690372495092 4.5283147931154e-05 -399.955883948528 141.143268420481 -2.83368727693775 0.00490026198236806 ADCY7 other 6.19838968920553e-06 1 0.485208930082315 4.13690372495092 -2.83368727693775 1.83134137189464e-15 135.098267959122 19.2987468774967 7.00036478102387 1.51367934045502e-11 -189.037059475503 58.4025112437525 -3.23679676523712 0.00133580400065006 CEP89 other 2.53640780007408e-11 1 2.08706107461938e-07 7.00036478102387 -3.23679676523712 0.00206120421428241 86.9716951369311 24.5516229266825 3.54240106231067 0.000456654021384028 43.821705902672 67.1292089316388 0.652796399661107 0.514365190447101 TSHZ3 other 1 1 1 3.54240106231067 0.652796399661107 0.0110121925178373 -74.8480640473321 46.0631867858156 -1.62489982283163 0.105174574561535 -317.931221575699 111.457211388244 -2.85249574806098 0.00462181215812141 ECHDC2 other 1 1 1 -1.62489982283163 -2.85249574806098 2.02055263958745e-07 386.283987095126 71.8353964337172 5.37734885964682 1.46106768907744e-07 -175.911498829391 277.865973680587 -0.633080389438418 0.527133307117767 PLBD1 other 0.00219229961395239 1 0.00180763294492661 5.37734885964682 -0.633080389438418 0.743762242849789 6.98321676685922 22.7111206264199 0.3074800614962 0.758678014175051 -65.1474624375258 103.406267407352 -0.630014640997417 0.529134601421483 PRB2 other 1 1 1 0.3074800614962 -0.630014640997417 4.0482309413011e-06 86.2419407536484 19.1991790201595 4.491959820943 9.98227480291748e-06 -122.484769532362 78.3963402932695 -1.56237866556225 0.119222353762066 PYROXD1 essential 0.039943894697818 1 0.112041052387946 4.491959820943 -1.56237866556225 0.12858914083713 9.80301474868065 7.58793054331557 1.29192204550639 0.197346443949468 54.8507885550128 31.0001720052642 1.76937045851547 0.0778151898326494 KCNJ8 other 1 1 1 1.29192204550639 1.76937045851547 0.392240353967584 -5.01191367849451 3.69416535546376 -1.35671070356441 0.175829460994575 -1.37690759292199 16.8097704939165 -0.0819111476519149 0.93476857902819 BCL2L14 other 1 1 1 -1.35671070356441 -0.0819111476519149 2.03052439140979e-05 -26.0052614644582 35.1106201271279 -0.740666538224014 0.459467338847277 -254.885731979994 57.0406028967697 -4.46849645753707 1.11270623204947e-05 PSPC1 other 0.188412358278915 0.163567816111272 1 -0.740666538224014 -4.46849645753707 0.124286828232044 12.5549202046235 6.72647176469061 1.86649415084566 0.0628867358597067 -4.44306890735723 17.4797875105029 -0.254183233330929 0.799517255290451 ZNF549 other 1 1 1 1.86649415084566 -0.254183233330929 0.019269785227989 36.7372119497762 14.4741983652121 2.5381172084854 0.0116280486132024 -14.9516429769202 36.955950649786 -0.4045801207662 0.686061626882815 A1BG other 1 1 1 2.5381172084854 -0.4045801207662 0.334923825425208 48.1080246202077 32.7235407605908 1.47013506185567 0.142513874826499 20.4986587713083 85.1727647916693 0.240671520073905 0.809964800772269 ZSCAN18 other 1 1 1 1.47013506185567 0.240671520073905 3.52866587353302e-05 31.9904270597338 7.43889306755544 4.30042840637935 2.2665556597322e-05 -5.614161383157 19.3311255414455 -0.290420822684141 0.771682432749833 ZNF211 other 0.319979421411974 1 0.248097182514286 4.30042840637935 -0.290420822684141 0.442097637417207 11.695008211512 49.9257675606353 0.234247940150511 0.814943241465099 -64.7521260945869 69.7543228067153 -0.928288362486306 0.353962063369261 PDZRN3 other 1 1 1 0.234247940150511 -0.928288362486306 0.287853912345484 2.39112198800976 1.82087644657764 1.31317091420668 0.190066207674217 4.78331883935278 5.71987626587891 0.836262642233535 0.403631182064236 LHX4 other 1 1 1 1.31317091420668 0.836262642233535 1.58716850080356e-07 107.355461031833 18.9377437187444 5.66886227980651 3.21893808179735e-08 -66.9940949007084 64.818979596289 -1.033556765595 0.302126329285548 RNF2 other 0.00173191826807685 1 0.00040838667443763 5.66886227980651 -1.033556765595 0.000376627455341046 56.9229418221732 14.9387414451523 3.81042419344135 0.000166440783361677 -71.0434886737851 51.1314331479275 -1.38942885618423 0.165671397287421 TRMT1L other 1 1 1 3.81042419344135 -1.38942885618423 2.04463467762428e-18 106.003652488575 11.4191206675747 9.28299608826965 2.57558368181623e-18 -38.1984481157505 44.9557591522462 -0.849689758021625 0.396132840450422 SEC22A other 2.92628115061587e-14 1 3.7925469714744e-14 9.28299608826965 -0.849689758021625 0.106785286095629 1576.045846635 1076.52868321627 1.46400729604934 0.144173593251733 -5285.90105114895 4238.16908604696 -1.24721334704445 0.213231309014661 CSTA other 1 1 1 1.46400729604934 -1.24721334704445 0.158715682821394 13.044011396303 6.80552287083218 1.91668026746459 0.0561746069447235 4.52821494883319 26.7726277826184 0.169135991640427 0.865797210948181 POPDC2 other 1 1 1 1.91668026746459 0.169135991640427 2.11875715897459e-08 759.113011916645 124.20054382975 6.11199426757108 2.87712875871522e-09 453.898515182276 488.599479197119 0.928978712642379 0.353604729407766 B4GALT4 other 0.000242237505985564 1 3.78169804045528e-05 6.11199426757108 0.928978712642379 3.21710411199537e-29 1770.09091749119 141.863055932476 12.4774621965969 2.19488962197974e-29 205.308123607682 582.7659224451 0.352299466561591 0.72484559505515 NAA50 essential 4.85396668417861e-25 1 3.33118397927865e-25 12.4774621965969 0.352299466561591 0.0369600438503495 -5.01853605275054 2.62772663690954 -1.90983947198283 0.0570533888489602 -21.146020819294 10.3373610668431 -2.04559177942614 0.0416190377002105 CD80 other 1 1 1 -1.90983947198283 -2.04559177942614 1.9601323713745e-05 26.0320527978331 18.4170802406793 1.41347338761841 0.158497791423101 -134.693315214266 39.4388566008361 -3.41524391991146 0.000720179804940182 KIF18A essential 0.182057094653263 1 1 1.41347338761841 -3.41524391991146 1.14954672636681e-10 342.875211985179 48.8921332564146 7.01289121885869 1.41520715992706e-11 -73.7885483468723 160.369224952932 -0.460116636271883 0.645747938264605 DESI2 other 1.43371467712469e-06 1 1.95284435998334e-07 7.01289121885869 -0.460116636271883 0.547334751913136 -12.239701749859 49.8405569989881 -0.24557714614039 0.80617208432904 -130.754180407592 122.856581413233 -1.06428307627895 0.288028765223964 MAPK8IP1 other 1 1 1 -0.24557714614039 -1.06428307627895 3.45051023710308e-08 120.905349957607 27.268113596638 4.43394624747765 1.28606815791788e-05 -106.94478204034 67.2156857745121 -1.59106882282071 0.112613291853684 CRY2 other 0.000390114687406874 1 0.143216550065735 4.43394624747765 -1.59106882282071 3.86827140033326e-07 82.8307902579556 25.4931255365378 3.2491422104849 0.00128464109240665 -158.476968414068 62.8403541521621 -2.52189807890533 0.0121731156772191 PEX16 other 0.00412396413989529 1 1 3.2491422104849 -2.52189807890533 7.17150407872876e-10 39.7181276146369 9.09051751435125 4.3691822332374 1.68730058179869e-05 -79.5499784719755 25.0801457481549 -3.1718307888154 0.00166163401436273 DEPDC7 other 8.72198326054991e-06 1 0.186446714288755 4.3691822332374 -3.1718307888154 1.02096441993344e-09 275.586639176742 48.673713602938 5.66191931490732 3.35546263227932e-08 -123.171080482324 128.202610857866 -0.96075329244955 0.337408466155221 CAT other 1.23291663351163e-05 1 0.000425405552520372 5.66191931490732 -0.96075329244955 3.0830859050517e-07 219.874719812469 61.5045995659675 3.57493132813001 0.00040693332186955 -210.857378129115 99.8147975506651 -2.11248615739651 0.035454616533003 ZMYM2 other 0.00330907610189199 1 1 3.57493132813001 -2.11248615739651 2.70403327710833e-07 3811.10862677402 923.665569553813 4.12606981617277 4.75761094417179e-05 -2119.42872381938 1500.34959645225 -1.41262325049509 0.158779470489895 GJB6 other 0.00291332545275651 1 0.508874066588615 4.12606981617277 -1.41262325049509 0.000219622846227065 72.5751062494171 23.8846493348702 3.03856695703971 0.00258136594415788 -40.8355509276145 38.796860218885 -1.05254782725271 0.293376014513465 GJA3 other 1 1 1 3.03856695703971 -1.05254782725271 1.85217160280426e-20 161.761443381202 15.8940985519971 10.1774531504258 3.26228737039948e-21 -23.3156330706533 84.6499340259915 -0.275435927256532 0.783162508816975 TBC1D15 other 2.69602098504189e-16 1 4.86700652789899e-17 10.1774531504258 -0.275435927256532 0.518265768246881 -14.0421237564095 23.7283155771477 -0.591787634935758 0.554413280815579 -55.4460174460175 50.7449288396545 -1.09264154495551 0.275378273890326 ADGRB2 other 1 1 1 -0.591787634935758 -1.09264154495551 0.000348113503996062 1.4683050397336 0.804372378112898 1.82540460076256 0.0688778355523989 -5.31993217707504 1.720215619824 -3.09259613490739 0.00215996254070567 HCRTR1 other 1 1 1 1.82540460076256 -3.09259613490739 7.43596465485242e-07 61.1947796429066 28.5733864011215 2.14167053158616 0.0329771311316995 -253.555063015291 58.4884621104541 -4.33512959421736 1.95552856846054e-05 ZCCHC17 other 0.00776655964862664 0.285644057995031 1 2.14167053158616 -4.33512959421736 0.0640076085531198 138.045811482603 58.814511817252 2.34713860945642 0.0195292979576535 45.3798367614964 120.390712450981 0.376938019865722 0.706470284155692 FABP3 other 1 1 1 2.34713860945642 0.376938019865722 0.0482369048570072 32.3822802394243 100.611491038489 0.321854689809104 0.747774913206739 -502.537340912341 216.958269250387 -2.31628572005418 0.0211801272257389 KHDRBS1 other 1 1 1 0.321854689809104 -2.31628572005418 0.0263695485161865 22.8480667351941 18.2218133198511 1.25388545772792 0.210807523555999 -82.3003396721224 39.9268339207553 -2.06127888415765 0.04009161064639 TMEM39B other 1 1 1 1.25388545772792 -2.06127888415765 0.0725940471234964 0.89291974956737 5.39745844551354 0.165433371758439 0.868707351742069 -14.4050139420257 7.76580809275719 -1.85492788000525 0.064526133159096 CCRL2 other 1 1 1 0.165433371758439 -1.85492788000525 0.0311165691025894 -14.87255416997 7.113967877303 -2.0906130624262 0.0373514629251517 -25.4752509335792 10.2355043342845 -2.48891017985779 0.0133214441214653 CCR2 other 1 1 1 -2.0906130624262 -2.48891017985779 2.74911562557224e-07 74.8337114900559 13.4624153744562 5.55871360439868 5.92064447060111e-08 -58.4150033679592 51.9411453912438 -1.12463833687054 0.261623726617324 POLR3GL other 0.00296024770561619 1 0.000743912865112042 5.55871360439868 -1.12463833687054 5.82551390517628e-05 1234.68369010013 275.916934598282 4.47483838531968 1.06963977805167e-05 371.3441673689 1992.16673997802 0.186402151946878 0.852249391330716 TNFSF10 other 0.515616235747152 1 0.119735476755104 4.47483838531968 0.186402151946878 4.16349269006129e-31 236.076275036556 17.7915758929293 13.2689918227186 3.9562265877013e-32 19.793394769953 119.402949348914 0.165769730797131 0.868446224211904 ZNF639 other 6.30227888494578e-27 1 6.02137686648137e-28 13.2689918227186 0.165769730797131 8.98879588033581e-35 281.620625611417 19.9544977218382 14.1131402823139 2.84112326573927e-35 194.895486350477 133.481949129263 1.46008870579004 0.14527836168738 PIK3CA og 1.36683630156386e-30 1 4.33384942955869e-31 14.1131402823139 1.46008870579004 1.53039392396686e-12 562.886470689984 106.093885553915 5.30555052961967 2.10575239609118e-07 -385.566952283616 203.170167040276 -1.89775377901413 0.0586311772356492 PDS5A other 2.00818290702932e-08 1 0.00258839084527528 5.30555052961967 -1.89775377901413 0.333244034792618 -9.33508408666233 7.15246053442508 -1.30515702138197 0.192777069840906 -0.942202989925218 14.7057988865277 -0.0640701669589938 0.94895436029187 TMEM156 other 1 1 1 -1.30515702138197 -0.0640701669589938 3.73297874966107e-07 30.0179995192913 8.35126455477241 3.59442564924341 0.000376501710878176 -27.324045466773 15.9988799823427 -1.70787239462571 0.0886328968432113 LIAS other 0.00398644800676305 1 1 3.59442564924341 -1.70787239462571 0.947256377172878 -4.99227193269738 61.6444345958266 -0.0809849577732255 0.935504541704399 31.1612558853676 122.693308408307 0.253976816581285 0.799676580689366 CPXM2 other 1 1 1 -0.0809849577732255 0.253976816581285 0.00234235114453524 37.2107008117056 195.503870730171 0.190332297118878 0.849170574185476 -1483.21607002847 439.33844260713 -3.3760215956217 0.000826920789392707 TMEM54 other 1 1 1 0.190332297118878 -3.3760215956217 0.0194142729762486 4.94664137785572 3.25846759809123 1.51808825128517 0.129988796771567 -15.1438125354285 7.68308927798418 -1.9710577330948 0.0495868551255363 ZSCAN20 other 1 1 1 1.51808825128517 -1.9710577330948 0.0123619654522964 32.6010535603134 12.1902788972584 2.67434845708455 0.00787446324211821 -19.466671024696 28.9000799865515 -0.673585368405718 0.501064229441083 CSMD2 other 1 1 1 2.67434845708455 -0.673585368405718 3.46521507484654e-05 -3.41820052589471 22.5049240928688 -0.151886783167505 0.879372851671517 -228.60279390624 50.573312257325 -4.52022586029312 8.7347517541401e-06 HPCA other 0.314398963740827 0.128724036600763 1 -0.151886783167505 -4.52022586029312 0.00694351163821909 40.4467243383133 29.5298469906768 1.36968960086665 0.171744169110559 -107.618896242563 54.7293071182627 -1.96638514004962 0.0501181641829132 LRIF1 other 1 1 1 1.36968960086665 -1.96638514004962 0.3902870301694 -0.820859141882646 4.17455119704417 -0.196634105832469 0.844238701669934 -9.96091899068122 7.65026411721604 -1.30203596085857 0.193840520086552 TMIGD3 other 1 1 1 -0.196634105832469 -1.30203596085857 7.58142608783605e-15 115.809983690235 36.3551431499651 3.1855185719533 0.00158731684362099 -402.319201178477 69.460969880163 -5.79201819197997 1.66243479946673e-08 CLCC1 other 1.04002003072935e-10 0.000252357602559049 1 3.1855185719533 -5.79201819197997 2.93810155252713e-13 328.868895164454 96.9886839754149 3.39079655156283 0.000784232147834624 -943.387234039634 185.308802898756 -5.09089271142212 6.0935091138842e-07 GPSM2 other 3.9138450781214e-09 0.00915366939087685 1 3.39079655156283 -5.09089271142212 0.0245964653931805 21.4569135488367 14.8409168524447 1.44579433751778 0.149232232334497 -79.2477480152237 38.341846032757 -2.06687356543863 0.0395654297957978 GTDC1 other 1 1 1 1.44579433751778 -2.06687356543863 0.114820121429892 -249.042876526339 119.292933389253 -2.08765824974487 0.0376344327065697 -122.286999355176 305.409100442025 -0.400403914546711 0.689131321774379 CXCR4 other 1 1 1 -2.08765824974487 -0.400403914546711 0.000695974825090878 12.1862443525906 6.04748660355715 2.01509240970002 0.0447441785479821 -46.4375128740334 15.629468275798 -2.97115116487624 0.00319516937416883 ZRANB3 other 1 1 1 2.01509240970002 -2.97115116487624 0.0889685226796384 12.5265605226028 19.0316978005325 0.658194589567949 0.510890813423549 -98.8718729245075 50.0920104039717 -1.97380524612899 0.049271918849873 ACVR2A other 1 1 1 0.658194589567949 -1.97380524612899 8.24543403999083e-05 34.6428842280635 18.1345152017366 1.91032866567869 0.0569845417309593 -71.8888610537829 24.9448605820237 -2.88191071733586 0.00421989991711872 POLK other 0.716445763734804 1 1 1.91032866567869 -2.88191071733586 0.137876134246255 -3.34650003626803 1.73847371337763 -1.92496441592217 0.0551255970339446 -4.08527184666975 3.2481150972866 -1.25773617138213 0.209409994744675 FLT3 og 1 1 1 -1.92496441592217 -1.25773617138213 0.0209943545652823 41.7013651686905 38.3952462785918 1.08610750576021 0.278251470803823 -138.970271728831 71.8694983607487 -1.9336474429148 0.0540409549717434 RPL21 other 1 1 1 1.08610750576021 -1.9336474429148 2.24474283517941e-07 32.9780831688676 18.88045441797 1.74667846646105 0.0816555884990118 -149.998958503092 35.4595004276247 -4.2301486680347 3.0552333700684e-05 MTIF3 other 0.00242926069623116 0.443925408670939 1 1.74667846646105 -4.2301486680347 2.63794634065709e-05 270.807242898914 79.1131012070034 3.4230391523944 0.000700030682799398 -228.303629531515 148.33301779955 -1.53912886637305 0.124764150136569 GTF3A essential 0.242189853535728 1 1 3.4230391523944 -1.53912886637305 0.536664513574416 6.01139924708835 16.5935158541966 0.362273993040963 0.717387170437962 34.581654385897 31.0602945955627 1.11337174473668 0.266387035401873 RASL11A other 1 1 1 0.362273993040963 1.11337174473668 0.000473707252807221 117.250906603348 40.4874376364466 2.89598239474161 0.00404071848250256 -88.9200862465275 67.9011000921116 -1.3095529546046 0.191289485021609 UBL3 other 1 1 1 2.89598239474161 -1.3095529546046 8.62937911898089e-31 644.514714404617 49.1614417245752 13.1101670698651 1.40065364925627e-31 514.998072586112 315.338997719493 1.63315694002499 0.103444701242578 FYTTD1 other 1.30553876691062e-26 1 2.13081439661357e-27 13.1101670698651 1.63315694002499 8.8203244368384e-09 14.1572114681229 16.6797396074832 0.848766935292652 0.396645468376843 -155.061488174117 30.0783184327804 -5.15525788187432 4.44451486798237e-07 MTERF4 other 0.000102677396769236 0.00668499481293228 1 0.848766935292652 -5.15525788187432 0.137395781429898 15.108777945072 8.14789039819065 1.85431776898068 0.0646193733870643 15.9683405126001 16.9448046287229 0.942373834486847 0.34671663850607 PAEP other 1 1 1 1.85431776898068 0.942373834486847 3.13926638378587e-14 367.817322673028 48.9240137484084 7.51813464374628 5.71002044939171e-13 -269.769423624495 101.745091564293 -2.65142445180293 0.00841682546779578 MRPS2 other 4.25590343649851e-10 1 8.03399877229414e-09 7.51813464374628 -2.65142445180293 0.0123113259460124 234.947359303345 90.2806008449139 2.60241244635648 0.00968773104032964 -428.2999059886 307.057819049288 -1.39485100009731 0.164028206828298 FMOD other 1 1 1 2.60241244635648 -1.39485100009731 0.341762757795854 29.28848025695 19.9865439331319 1.46540994555833 0.14379095160509 -3.07927711402057 67.9772236007001 -0.0452986596232338 0.96389751043334 MYOG other 1 1 1 1.46540994555833 -0.0452986596232338 0.0137388070271262 -19.1896957352407 6.53155869696382 -2.93799636894651 0.00354330218916812 4.31414375865141 22.1813820447427 0.194493911603399 0.845912578762497 LAX1 other 1 1 1 -2.93799636894651 0.194493911603399 3.68379077173673e-11 287.854040977625 71.721126018694 4.01351814948634 7.45557674009909e-05 -462.566942004674 109.208595431685 -4.23562760949555 2.98312852266423e-05 KIAA1191 other 4.67252021487086e-07 0.43356789948402 0.783506559617014 4.01351814948634 -4.23562760949555 3.51215924398004e-07 884.166832056152 162.743991431723 5.43286928308559 1.10006640202265e-07 -810.467100911771 569.662676939299 -1.42271406170801 0.155793150216633 COPA essential 0.00376117133437822 1 0.00136771255763476 5.43286928308559 -1.42271406170801 0.0748416347734719 -6.89364077049231 3.02590364089011 -2.27820895461973 0.0233730183374661 2.67714187498144 10.591754282695 0.252757173507641 0.800618148510271 CD244 other 1 1 1 -2.27820895461973 0.252757173507641 0.25949434990814 -8.58915171783121 5.4258118168972 -1.58301688441952 0.114405401451937 9.37103535294319 18.9922986218467 0.49341238464752 0.622059684078182 LY9 other 1 1 1 -1.58301688441952 0.49341238464752 0.745563973072689 -0.0775082268309427 4.2856338018211 -0.0180855925669634 0.985581877883807 -9.77534246575346 13.1511135228282 -0.743309108296041 0.45784163295331 HS3ST2 other 1 1 1 -0.0180855925669634 -0.743309108296041 0.00587905190193398 79.420116167744 40.4352415504845 1.96413111737161 0.0503856121276906 -255.722420374031 138.833608311331 -1.84193455377592 0.0664157275337695 RBBP6 essential 1 1 1 1.96413111737161 -1.84193455377592 0.00470879043278416 11.83432177421 23.1131482281834 0.512016868380553 0.608992378005758 -227.723762765209 74.9959030338163 -3.03648270842911 0.00259023518341151 ZC3H7A other 1 1 1 0.512016868380553 -3.03648270842911 0.000212780167250823 28.2484509735426 13.2987644138457 2.12414101750178 0.0344249181891142 -87.9598885318444 29.0822121655183 -3.02452537073969 0.00269184187663704 SERAC1 other 1 1 1 2.12414101750178 -3.02452537073969 0.000450420106078818 265.980396794313 212.051815548545 1.25431794161377 0.210644765599907 -1497.24505438221 495.153438564293 -3.02380017540321 0.0026987664920668 ANXA11 other 1 1 1 1.25431794161377 -3.02380017540321 0.487808513768873 178.309900008202 277.464230062272 0.642641035091923 0.520921569125446 -382.63104294204 567.933390928456 -0.673725209775949 0.500976964583877 LDB3 other 1 1 1 0.642641035091923 -0.673725209775949 6.57755157919847e-08 85.2103806420831 23.2888402341099 3.65885032425444 0.000296474978964697 -131.280889296765 47.5391052081633 -2.76153471383012 0.00608738306585651 FAM35A other 0.00073241036834375 1 1 3.65885032425444 -2.76153471383012 3.93286888580278e-05 449.602021054129 195.687516551252 2.29755085545467 0.022234362076034 -1265.83589925622 455.319833584341 -2.78010270119662 0.00575682403858072 FAM213A other 0.355216717765708 1 1 2.29755085545467 -2.78010270119662 0.0184766884975121 43.3360311398911 19.2934760145137 2.24614948116613 0.0253784256240728 -59.3825116282594 55.429268097882 -1.07132050748706 0.284835196981724 ZNF205 other 1 1 1 2.24614948116613 -1.07132050748706 7.88705568945609e-05 113.708821399002 39.7600546142566 2.85987588553841 0.00451738978421198 -280.885704090345 113.823863817655 -2.46772245001559 0.0141220195434885 NAA60 other 0.68699747010229 1 1 2.85987588553841 -2.46772245001559 0.000120067858922305 1205.01918157483 475.991579525752 2.53159768661335 0.0118327381815977 -2509.38727535471 1010.00459486525 -2.48453055373426 0.0134832157965422 RPL5 other 1 1 1 2.53159768661335 -2.48453055373426 3.03310948771156e-05 62.8356232782034 30.5416425684994 2.05737537322279 0.0404601051245565 -215.732621448691 64.9006922849709 -3.32404191470617 0.000990166729542102 ODF2L other 0.277104882797328 1 1 2.05737537322279 -3.32404191470617 0.602282282227136 -9.88031635261515 12.8720142452712 -0.767581216455297 0.443302019624881 10.2316911479761 27.1088326654919 0.377430163601273 0.706104150568678 PTGFR other 1 1 1 -0.767581216455297 0.377430163601273 4.83564317132747e-05 26.1049128795787 10.1380623688881 2.57494104195789 0.0104774921235264 -54.8812440767157 21.096614650242 -2.60142420888776 0.00971783279879793 TRMT13 other 0.432306499516675 1 1 2.57494104195789 -2.60142420888776 0.326164482628897 17.6250813492307 12.9618798838556 1.35976274330264 0.174868316751877 28.7105600882908 26.9727858344608 1.06442694738672 0.287942895810691 LRRC39 other 1 1 1 1.35976274330264 1.06442694738672 0.00173338973732309 4.61896721470366 8.17494397719513 0.565015152102419 0.572460582711486 -54.789127340805 17.2945261235063 -3.16800396550541 0.00168345602573879 RWDD3 other 1 1 1 0.565015152102419 -3.16800396550541 0.0208068601856428 43.8835458893443 38.6254624118138 1.13612998134418 0.256754970108607 -169.797718467854 82.5617940170088 -2.05661372175214 0.0405363945788493 ZNF644 other 1 1 1 1.13612998134418 -2.05661372175214 6.1674174187563e-06 19.155540068248 10.6363865431552 1.80094433297699 0.0726530497256789 -86.3334087633182 22.5693053058903 -3.82525769372203 0.000157057568363715 CCDC18 other 0.0599719669799863 1 1 1.80094433297699 -3.82525769372203 4.85122948637138e-06 37.0995314618587 14.9208894142402 2.48641555016496 0.0134133764954643 -106.084778020243 31.660574506116 -3.35069024094147 0.000902564621076666 RPAP2 other 0.0476099661792488 1 1 2.48641555016496 -3.35069024094147 3.53031969284989e-18 167.880632259753 65.5691102056092 2.5603616052333 0.0109299918588881 -532.04252218853 96.8797190679357 -5.49178432087981 8.29784606056689e-08 PQLC1 other 5.04164955335893e-14 0.00125471730281832 1 2.5603616052333 -5.49178432087981 2.27202414996527e-05 24.1879360057627 6.6653633976203 3.62889981578476 0.000331212718109747 -62.3568100288745 27.4103621198306 -2.27493565230068 0.0235710290991931 BBS9 other 0.21000319218129 1 1 3.62889981578476 -2.27493565230068 0.000449991940513458 248.448592302516 80.7093938430959 3.07831072037928 0.0022618920408895 -609.582961237451 323.667174401487 -1.88336355815096 0.0605578239986892 ZMIZ2 other 1 1 1 3.07831072037928 -1.88336355815096 5.11192830358723e-20 518.589413991492 56.4106258245932 9.19311577226649 5.06381589715666e-18 -563.858801475671 227.192336707612 -2.48185660505502 0.0135844588368324 SEPT7 other 7.4194527398265e-16 1 7.44127746087171e-14 9.19311577226649 -2.48185660505502 0.598672025931947 5.27711913943317 11.7566093000697 0.448864039345245 0.653834505502644 -38.4274003781251 47.3494399254973 -0.811570325617141 0.417643364449738 EEPD1 other 1 1 1 0.448864039345245 -0.811570325617141 3.04325193074591e-16 141.250021339597 16.4562290553069 8.58337720415027 4.10970850950255e-16 -62.2544851590397 68.6778410503998 -0.906471202456025 0.365370684861763 KLHL7 other 4.25477052437586e-12 1 5.9681186974996e-12 8.58337720415027 -0.906471202456025 1.60120030671855e-24 161.584990016806 15.2737942294826 10.5792305165997 1.2529848315422e-22 -145.809583147795 62.7178629165239 -2.32484935498941 0.0207052823069326 HERPUD2 other 2.38178545624384e-20 1 1.87759777006598e-18 10.5792305165997 -2.32484935498941 2.77744530941553e-06 433.71335675312 99.8310930593664 4.34447168173551 1.88199460825907e-05 -765.954961326428 412.796633647972 -1.85552618139717 0.0644491747281899 CBX3 other 0.0277688982035365 1 0.207226426315406 4.34447168173551 -1.85552618139717 0.301736725613825 144.045668585094 375.205471200149 0.383911428914784 0.701301468601926 -2163.49182790324 1551.45607136264 -1.39449119303975 0.164145811596375 HNRNPA2B1 og 1 1 1 0.383911428914784 -1.39449119303975 0.188520046089399 -30.2031359156064 16.5583536995513 -1.82404220030793 0.0690870420975207 -12.9022176344929 67.072512813539 -0.19236222251522 0.84758165297144 WIPF3 other 1 1 1 -1.82404220030793 -0.19236222251522 3.37064087045982e-09 243.193933636547 40.1003006675088 6.06464115201995 3.72671942456031e-09 -173.112941767178 170.441286223209 -1.01567493183823 0.310551519328939 FAM126A other 3.99522062375602e-05 1 4.88237511811646e-05 6.06464115201995 -1.01567493183823 0.334604004819932 15.8235997762956 13.0539448992802 1.21216995309732 0.226350008110701 56.9700329342555 53.6653527859841 1.06157939856373 0.289234762860242 HOXA7 other 1 1 1 1.21216995309732 1.06157939856373 6.03130863393334e-06 1110.60361568288 233.201409675902 4.76242239369981 2.90402256417536e-06 -534.845635398428 932.467315919414 -0.573581107098719 0.56665418546454 INHBA other 0.0586906643168053 1 0.0337215100152043 4.76242239369981 -0.573581107098719 2.27834780837622e-11 986.432444318739 143.285286988571 6.88439451845059 3.10388610946946e-11 -630.288223690617 587.623177978828 -1.07260613146428 0.284261168952093 FKBP9 other 2.90443778611801e-07 1 4.25666941052641e-07 6.88439451845059 -1.07260613146428 0.000290755511407816 65.7746370261158 23.4595242347112 2.80374982749199 0.0053606185723164 -232.405831674014 96.3421190739592 -2.41229727878004 0.0164163578117531 NT5C3A other 1 1 1 2.80374982749199 -2.41229727878004 0.013833713247699 59.1025865345477 24.9146835042458 2.37219896951434 0.0182755010090737 -142.132956556744 107.387497995236 -1.32355217516149 0.186599572660961 ARL4A other 1 1 1 2.37219896951434 -1.32355217516149 4.9885165172409e-13 157.737034692321 21.5000134659852 7.33660166966284 1.82687911494686e-12 -174.835917455752 103.173626234899 -1.69457955328329 0.0911311423672042 CCZ1 other 6.61277749525454e-09 1 2.55580388181066e-08 7.33660166966284 -1.69457955328329 0.00670917372136921 -31.2166708534752 9.8191028987812 -3.17917748446754 0.00162135476222479 -32.3601079727005 40.0809809957779 -0.807368162373802 0.420054107374487 RAMP3 other 1 1 1 -3.17917748446754 -0.807368162373802 9.79363597341194e-15 139.906171413474 18.0527797718483 7.74984092098911 1.26794746345832e-13 -156.949219905369 82.1662774961066 -1.91014154088708 0.0570200404278916 MRM2 other 1.34172812835744e-10 1 1.80162655082793e-09 7.74984092098911 -1.91014154088708 0.0214524319141925 42.4803244063972 17.1693013445862 2.4742022726389 0.0138732758511822 -58.3353709710645 71.8618858324389 -0.81177066667977 0.417528546272604 TWIST1 other 1 1 1 2.4742022726389 -0.81177066667977 9.40797301621543e-61 460.003644929024 27.6958526363513 16.6091165695062 9.34565571957084e-45 -532.975245972033 70.7756868414489 -7.53048496959131 5.56298800323761e-13 SMU1 essential 1.44384161879858e-56 8.52861690776357e-09 1.43091334722349e-40 16.6091165695062 -7.53048496959131 1.312376080352e-05 59.1242822750133 16.2256589012247 3.64387558218364 0.000315394460751382 -120.134648376987 51.705919037176 -2.32342158526592 0.0208116085591908 GLIPR2 other 0.123993292071657 1 1 3.64387558218364 -2.32342158526592 1.54342179227294e-55 79.4138731967963 4.2305486729444 18.7715304411155 3.82932638868252e-53 -15.3425881415553 12.4768654461433 -1.22968290455499 0.219742342667499 SLC25A51 other 2.36776337152591e-51 1 5.87380374760012e-49 18.7715304411155 -1.22968290455499 1.28279391636218e-40 1048.68566580783 72.3038567095852 14.5038689985787 1.21628902763753e-36 -708.317821906617 228.039479555972 -3.10611927060095 0.00207324140812105 CLTA other 1.96010910420142e-36 1 1.85678682959146e-32 14.5038689985787 -3.10611927060095 0.019101555261721 12.2453975802593 5.72220445090318 2.13997903872982 0.0331444587956084 42.0816805569592 18.4415127189617 2.2818996032625 0.0231794127525678 RECK other 1 1 1 2.13997903872982 2.2818996032625 0.587145597404125 -4.05187838708517 4.0090342487311 -1.01068689756583 0.312959630328109 -1.14860511141679 10.2579431855519 -0.111972262922511 0.910918336571027 TAF1L other 1 1 1 -1.01068689756583 -0.111972262922511 6.0109825213532e-18 205.642204537163 25.4508853484023 8.07996270943369 1.45960889986676e-14 -146.870031455945 63.5093727345533 -2.31257254058877 0.0214008360165323 ACO1 other 8.56565009292831e-14 1 2.09439281041882e-10 8.07996270943369 -2.31257254058877 0.000646292130889297 33.2949930978551 9.14808661597345 3.6395581388264 0.000320180654731998 -16.9971963942342 28.7450676073052 -0.591308276829886 0.554747594927544 PHF24 other 1 1 1 3.6395581388264 -0.591308276829886 9.00170398968355e-54 302.179484705528 17.7265940653006 17.046674820463 1.79822014298655e-46 -237.686183389786 52.3969591013799 -4.53625911629528 8.18717308747921e-06 DCAF10 other 1.38059134089777e-49 0.120744428694143 2.7541539709982e-42 17.046674820463 -4.53625911629528 1.71231684508311e-07 30.7567088108237 5.3866710793207 5.70978037417171 2.63521637062527e-08 12.001950547176 17.1691472624098 0.699041738284413 0.48504672051076 CNTFR other 0.0018647130442955 1 0.000335831974272484 5.70978037417171 0.699041738284413 0.00566296271165996 68.3058576549676 25.4112499098432 2.68801644536615 0.00756386797285688 -20.9877245433589 55.9184100950298 -0.375327633738005 0.707665471784528 KIAA1549 other 1 1 1 2.68801644536615 -0.375327633738005 0.000111990309879354 69.2810598194731 39.770871187813 1.74200508438203 0.0824683723900827 -237.733671901988 87.5172961899558 -2.71641929369011 0.00695801505869023 TRIM24 other 0.959532975046303 1 1 1.74200508438203 -2.71641929369011 8.10645151983066e-19 154.948093825224 29.1689827704034 5.31208424527041 2.04137491071709e-07 -306.563289481051 64.1351017556574 -4.77996106794995 2.68412262024622e-06 C7orf49 other 1.16465388985407e-14 0.0399665858154662 0.00251068700269094 5.31208424527041 -4.77996106794995 2.01745575630052e-05 1271.3740021273 304.492169888327 4.17539144797573 3.84535852599499e-05 -18.3020157121823 669.500080044056 -0.02733683872148 0.978208221936258 CALD1 other 0.187240068742251 1 0.41437583476122 4.17539144797573 -0.02733683872148 0.892620186686933 -4.34083947112186 10.3368891138621 -0.419936735637481 0.674814365387635 -8.8699200561077 24.1526242175893 -0.367244568383096 0.713680105812487 SFTPA1 other 1 1 1 -0.419936735637481 -0.367244568383096 0.0486749093159782 464.174202162231 621.755908474262 0.746553745345624 0.45588110241667 -2746.39571750618 1454.89841926489 -1.88768898305206 0.0599723814400774 PLAU other 1 1 1 0.746553745345624 -1.88768898305206 0.34186032039993 -95.0915323188187 106.56986207352 -0.892292909727304 0.372906435575885 -317.447114660239 223.222050088561 -1.42211360631396 0.155967230835269 SRGN other 1 1 1 -0.892292909727304 -1.42211360631396 0.00334794363891629 58.5914714829068 89.0285952060822 0.658119690053291 0.510935880317784 -594.348308691377 206.367857451576 -2.8800430262297 0.00424518816792904 CHST3 other 1 1 1 0.658119690053291 -2.8800430262297 0.661846008113067 19.8564733758286 25.1388497217401 0.789871994765802 0.430194831322476 -8.74500616413323 57.4882532200973 -0.152118140216444 0.879190832235322 BICC1 other 1 1 1 0.789871994765802 -0.152118140216444 0.00116600232759089 11.6661141393226 30.2261230712948 0.385961312729576 0.699785038854538 -230.780893555115 69.1219779830141 -3.33874840230739 0.000942189281754675 CISD1 other 1 1 1 0.385961312729576 -3.33874840230739 0.830382167419495 28.9505741922661 48.1411856912848 0.601368117061295 0.548027350585192 33.2982479774448 110.584814657161 0.301110492255896 0.763528902128166 EGR2 other 1 1 1 0.601368117061295 0.301110492255896 1.67944423348735e-13 106.969658659923 18.4486361840105 5.7982420810398 1.60757149139131e-08 -130.825118402928 43.1600878583875 -3.0311596869816 0.00263502408036858 ECD essential 2.24810405094617e-09 1 0.000206428255209559 5.7982420810398 -3.0311596869816 8.99194042665211e-09 578.431863075974 96.9108244804554 5.96870232171671 6.34485405060418e-09 94.6446405173607 224.973251974924 0.42069285875776 0.674261758464094 P4HA1 other 0.000104630218804524 1 8.25402063443098e-05 5.96870232171671 0.42069285875776 0.00311873563534874 19.4487551492165 11.1254350546336 1.74813434743986 0.0813997881634755 -47.2451413882573 23.284315511691 -2.02905433765213 0.043280258029707 SLC25A16 other 1 1 1 1.74813434743986 -2.02905433765213 0.00675592474881733 -92.2504985670323 80.9564891460683 -1.13950715427625 0.255354708970293 -508.299903588362 159.539110364114 -3.1860520121259 0.00158633286098812 ZWINT essential 1 1 1 -1.13950715427625 -3.1860520121259 5.74857593855196e-11 237.920822660841 57.7193475144002 4.12202897133379 4.78951464997116e-05 -450.709808648487 120.899387793615 -3.72797428402108 0.000228207241557944 VPS26A other 7.25010397370174e-07 1 0.512094906374917 4.12202897133379 -3.72797428402108 0.0531326293096082 101.561237277502 58.6180268348699 1.73259392649986 0.0841313414362912 -226.907837470803 156.200601653719 -1.45266942040232 0.147295403440117 RBM19 essential 1 1 1 1.73259392649986 -1.45266942040232 0.190276843946497 13.922484492252 11.5000325354149 1.21064740029013 0.22692398045056 -37.9049322770253 32.2511959092878 -1.17530315414162 0.240747193441534 IFT81 other 1 1 1 1.21064740029013 -1.17530315414162 0.27039137517535 27.0310930110409 27.7233928533743 0.975028314680137 0.330285003799097 107.731742959429 75.9906586308616 1.41769718673917 0.157255221078351 ACADS other 1 1 1 0.975028314680137 1.41769718673917 0.427919201140014 -16.3154752224519 13.3343835499926 -1.2235642661157 0.222016840882344 10.0434236306329 37.3955303931563 0.268572835444285 0.788431478858401 HVCN1 other 1 1 1 -1.2235642661157 0.268572835444285 6.64462626862018e-08 419.402469805377 71.0972793455669 5.89899464038391 9.30240979144659e-09 183.460362822197 189.454309695629 0.968362045270646 0.333594901189027 DDX54 essential 0.000739414011172054 1 0.000120298763422987 5.89899464038391 0.968362045270646 0.00669855565045283 330.520718343103 111.080072130387 2.97551767841071 0.0031483802016433 -229.580326193154 300.112029459302 -0.764982085545782 0.444847765115445 MED13L other 1 1 1 2.97551767841071 -0.764982085545782 0.0145425367506464 -158.511709039972 83.0548215204682 -1.90851904968465 0.0572215048706515 -528.747323569511 203.102989191592 -2.60334584771044 0.00966331043887801 CDKN2C other 1 1 1 -1.90851904968465 -2.60334584771044 1.78318557231505e-06 391.353849642227 98.1587522384465 3.98694808886275 8.30219248187247e-05 -576.630413027088 240.038273877119 -2.40224362437416 0.0168660945681723 RNF11 other 0.0180708025898407 1 0.867911202054948 3.98694808886275 -2.40224362437416 8.90642168211459e-10 104.849126076778 15.7523587695374 6.65609053290101 1.22219635168565e-10 57.0147232765869 80.9387308725736 0.704418300879321 0.481684634705356 RASSF8 other 1.07945830787229e-05 1 1.65827600996709e-06 6.65609053290101 0.704418300879321 0.000341099387755562 113.307986908198 28.3177752743183 4.00130256740043 7.83172663290238e-05 15.0122299247676 145.502322881983 0.103175190797084 0.917888557719199 BHLHE41 other 1 1 0.820609838802366 4.00130256740043 0.103175190797084 2.66843950734786e-06 119.275602794219 23.1184376586904 5.15932800283249 4.35625341438063e-07 67.7936736257311 118.849892022662 0.570414263504796 0.568797052002647 SSPN other 0.0267190847870741 1 0.00528021476357076 5.15932800283249 0.570414263504796 1.73919636103843e-05 176.074276051095 37.6138717375618 4.68109949647286 4.22026695278899e-06 -11.0285800216773 193.369667127268 -0.0570336608916989 0.954553976723239 ITPR2 other 0.162458332084599 1 0.0485457307579317 4.68109949647286 -0.0570336608916989 1.97700329497794e-37 254.925466115776 17.4184500529475 14.6353702735243 1.82876897791993e-37 -51.6307002772639 97.4298050382342 -0.529927164043924 0.596531067378496 CCDC91 other 3.01433692385286e-33 1 2.79289598307932e-33 14.6353702735243 -0.529927164043924 0.520137073061828 3.65531631166178 5.35745476066608 0.682285987461576 0.495551701497172 -23.0480773266684 27.1079522150205 -0.85023306607046 0.39583122095873 NECAB1 other 1 1 1 0.682285987461576 -0.85023306607046 1.91609108158745e-08 176.736624319419 29.7025900526321 5.95020919072199 7.06492024498056e-09 -128.147712332032 151.863777520364 -0.843833298660357 0.399396881911177 WWP1 other 0.000219699003414817 1 9.17521192215626e-05 5.95020919072199 -0.843833298660357 9.16194904792283e-06 315.639519022044 99.753802961785 3.16418532076379 0.00170549591117617 -685.616988402324 244.004670075409 -2.80985191058202 0.00526345325408916 DDX39A other 0.0877439860319569 1 1 3.16418532076379 -2.80985191058202 0.0103671198697191 266.953823792611 108.065245999575 2.47030228195344 0.0140241715311297 -286.8618832531 264.33503198716 -1.08522083167181 0.278645868881157 PKN1 other 1 1 1 2.47030228195344 -1.08522083167181 0.0502590054930538 -99.3883205432288 69.2450366257571 -1.43531327855864 0.152180669655524 -388.946328109668 169.378127094566 -2.29631968886109 0.0223075422022811 ADGRE5 other 1 1 1 -1.43531327855864 -2.29631968886109 7.20351843644371e-05 46.496894769605 24.3306653680796 1.9110408230186 0.0569068028142199 -175.29711867433 52.9338882475956 -3.31162369660786 0.00103537474923489 WDR83 other 0.63088414466374 1 1 1.9110408230186 -3.31162369660786 0.00064859051762046 415.785579822427 208.074410230855 1.99825427529084 0.0465402947949885 -1372.31694099571 508.964333309329 -2.69629294468 0.00738495550693129 GIPC1 other 1 1 1 1.99825427529084 -2.69629294468 1.32829394626892e-25 103.034221859778 12.8282120983669 8.03184583086951 1.87265785989121e-14 -111.422350134447 23.8087616444861 -4.67988851323779 4.24864292737461e-06 SPRYD7 other 1.9846039851204e-21 0.0630796015427308 2.68426777636806e-10 8.03184583086951 -4.67988851323779 2.03507293641742e-07 154.105420239218 31.574350998873 4.88071537067283 1.67300672297437e-06 -43.8368062195863 58.6010109005923 -0.748055460919415 0.454977827838552 EBPL other 0.00220764712142562 1 0.019709692203361 4.88071537067283 -0.748055460919415 0.903989943315444 4.79228222132669 12.6175417120985 0.379811086079591 0.704340784719274 -1.82523596695762 23.325841756662 -0.0782495219678974 0.937679094737147 ATP7B other 1 1 1 0.379811086079591 -0.0782495219678974 1.49989271254846e-19 375.728233717084 48.869075370849 7.68846618983118 1.88752679998429e-13 -244.642852930209 91.6877945718666 -2.66821613577425 0.00801762520055247 ZC3H13 other 2.17004477651511e-15 1 2.67519173361774e-09 7.68846618983118 -2.66821613577425 0.000116886688359421 174.86732840198 43.6593002175484 4.00527098534883 7.72304695768571e-05 8.115101075653 61.3338349845926 0.132310348402176 0.894822763893424 NLN other 1 1 0.809993164922077 4.00527098534883 0.132310348402176 2.95575368153559e-06 37.2965163910097 22.9805342057531 1.62296124437667 0.10559169916405 -123.47252813177 32.2837124234739 -3.82460748355544 0.000157720969821064 CENPK essential 0.0294954659880436 1 1 1.62296124437667 -3.82460748355544 2.9325979666029e-09 304.097159353969 146.324452651217 2.07823883051744 0.0384890906735981 -1270.7918826163 299.514160225207 -4.24284408343426 2.89848895415638e-05 OPTN other 3.4842196441209e-05 0.421469278823879 1 2.07823883051744 -4.24284408343426 0.288944287071935 -42.5745200593168 63.4380631450746 -0.671119481721162 0.502631593296562 -202.421534568567 128.532725633986 -1.57486378329041 0.11628220301355 ITIH5 other 1 1 1 -0.671119481721162 -1.57486378329041 0.000135526167322456 73.3607340911182 18.2184935267282 4.02671790526979 7.07322502955064e-05 -29.4029765005056 49.6806901373713 -0.591839131445313 0.554377518375553 ATF1 other 1 1 0.744598398860795 4.02671790526979 -0.591839131445313 1.07367835462027e-12 191.344393414327 24.6985761346025 7.74718317248481 1.25326332968961e-13 146.726943308114 80.9235908135721 1.8131541350672 0.0707448412482645 TSFM essential 1.41339018602212e-08 1 1.78088719148893e-09 7.74718317248481 1.8131541350672 0.126558028072886 -32.5635630518709 16.4122668815327 -1.98409904536172 0.0480988429386971 4.807514492855 54.1462088629671 0.0887876472574807 0.92930621547821 ARHGAP9 other 1 1 1 -1.98409904536172 0.0887876472574807 0.142084372907826 -89.0601859884103 47.9586356739416 -1.85702084175012 0.0642297604664299 42.2118962466094 133.504348475439 0.316183680371843 0.752069878167697 NCKAP1L other 1 1 1 -1.85702084175012 0.316183680371843 0.872817629083109 5.14671365460493 43.0785563209165 0.119472751506902 0.904975795699642 64.1651928737637 123.079242571243 0.521332367126184 0.602495857875353 MMP19 other 1 1 1 0.119472751506902 0.521332367126184 0.823400357142454 119.821331799619 192.528880475663 0.622355105912361 0.534154382493982 89.1611868049419 522.426685350438 0.17066736693424 0.864593859442105 PFDN5 other 1 1 1 0.622355105912361 0.17066736693424 0.000558407611629081 105.519802676284 34.5513744440051 3.0539972540685 0.00244897373246387 -160.497021713788 91.4821003974613 -1.75440901571431 0.0803235955130174 SPATS2 other 1 1 1 3.0539972540685 -1.75440901571431 0.00110178446950017 126.869979428726 40.8519840291348 3.10560141554556 0.00206879760620975 -167.044040352457 116.717728755387 -1.43117966853641 0.153354590763942 ORMDL2 other 1 1 1 3.10560141554556 -1.43117966853641 0.40082630660985 500.119782667284 377.354264052601 1.3253322681351 0.186009389416139 0.946114833529587 1034.21338820904 0.000914815882598454 0.999270654443951 NR4A1 other 1 1 1 1.3253322681351 0.000914815882598454 0.950758126463804 -0.151427877441967 3.59272706181406 -0.0421484501429138 0.966406725307891 3.00785760352067 10.0012162334756 0.300749182229748 0.7638016804806 PDE1B other 1 1 1 -0.0421484501429138 0.300749182229748 0.00447167757522282 50.7434609209094 19.8104114290403 2.56145416780815 0.0108814943950286 -86.6478890093462 55.1713390847714 -1.57052358066225 0.117281579040252 HOXC13 other 1 1 1 2.56145416780815 -1.57052358066225 0.0872110323736584 14.4133477219842 54.5512907117921 0.264216438033217 0.791783227213573 -328.801943672285 155.857858654168 -2.10962698006689 0.0356667219162288 CDK2 essential 1 1 1 0.264216438033217 -2.10962698006689 1.69530508110955e-05 1842.11758782225 490.691846840693 3.75412308087587 0.000206559346016608 -3522.08213362256 1618.85639675328 -2.1756606334486 0.0303121032115348 LRP1 other 0.158561884236176 1 1 3.75412308087587 -2.1756606334486 0.00494643105558443 21.7169420417465 7.8369179476785 2.7711074923503 0.00591333704346909 49.5460731591008 21.8255566785999 2.27009436179381 0.023866572455058 HOXC11 other 1 1 1 2.7711074923503 2.27009436179381 0.04312187496609 131.659192014178 63.8960664082399 2.060521083927 0.0401592808556581 -174.302542587436 175.119704819564 -0.995333693412911 0.320328386828993 ATG101 other 1 1 1 2.060521083927 -0.995333693412911 0.591321140831096 2.02833169316827 2.88407136182195 0.703287623190751 0.48238788537443 -4.78821986427411 8.0320431313458 -0.596139710155146 0.551503340641867 NFE2 other 1 1 1 0.703287623190751 -0.596139710155146 0.617261132560321 5.893535224092 8.15172298281952 0.722980311832622 0.470220065364392 -11.9877632231863 23.2901929884049 -0.514712919259811 0.607108963984963 IKZF4 other 1 1 1 0.722980311832622 -0.514712919259811 0.0608362038737828 55.5923758222404 23.43971537697 2.37171718718313 0.018297057240438 39.8546146981411 65.2788302628398 0.61052893468939 0.541944844570909 SMUG1 other 1 1 1 2.37171718718313 0.61052893468939 0.0266938095481839 1349.16678867271 1041.36306625197 1.29557772154199 0.196057713671574 -5459.18150966418 2670.95588971487 -2.04390552861094 0.0417838336114136 TUBA1B essential 1 1 1 1.29557772154199 -2.04390552861094 6.26505880225423e-08 39.5403252975755 7.12919188530346 5.54625628454275 6.11895000126387e-08 -22.634325243635 23.3584237331591 -0.969000541397994 0.333276728651182 EEF1AKMT3 other 0.000698491405863324 1 0.000768295362158691 5.54625628454275 -0.969000541397994 3.72433006176599e-16 87.5662071105595 16.2339964743794 5.3940018558435 1.34481306721378e-07 -166.660194197814 42.6628398765304 -3.90644867243112 0.000114370283172073 KBTBD4 other 5.20139936426239e-12 1 0.00166622339027788 5.3940018558435 -3.90644867243112 0.00158541928349394 10.1535417598457 3.17112099142734 3.20187775467867 0.00150253199634074 -9.02144364802465 6.66539285999424 -1.3534751570566 0.176859143472212 SARDH other 1 1 1 3.20187775467867 -1.3534751570566 0.536669874370254 21.7039338341385 34.465321329349 0.62973252524579 0.529318959110211 -69.380672456645 87.4636032997727 -0.793251933822686 0.428218821828848 ATPAF1 other 1 1 1 0.62973252524579 -0.793251933822686 0.0756270383282962 -3.98388673238572 28.8217801008736 -0.138224867389956 0.890149641321233 -165.658409896954 73.141831960506 -2.26489281792126 0.0241877015960029 STIL essential 1 1 1 -0.138224867389956 -2.26489281792126 0.000849186176305421 53.5703912740189 36.4805020681587 1.46846639264805 0.142962943033712 -155.185386336664 62.7393149602452 -2.47349507139179 0.0139002332387996 HJURP essential 1 1 1 1.46846639264805 -2.47349507139179 0.154780352110792 174.831006370171 134.311287226066 1.30168513742188 0.193963260082745 -332.464920226755 313.293783272652 -1.06119220354085 0.289405318921355 COL10A1 other 1 1 1 1.30168513742188 -1.06119220354085 0.00132189838243092 124.313887763907 92.6360275256549 1.3419604778441 0.180560208601134 -631.595210992079 210.461644556489 -3.00099912420173 0.00290251278451139 AMD1 other 1 1 1 1.3419604778441 -3.00099912420173 0.0236427227885908 22.8773495213013 16.7833672373083 1.36309652275537 0.173825624609302 -68.9707456669931 36.517160790616 -1.88872147159691 0.0598476968580809 NDUFAF4 other 1 1 1 1.36309652275537 -1.88872147159691 9.97711237436363e-05 6.06413379455379 6.70976683243702 0.903777127580344 0.366797722073245 -54.7087185776705 14.5083771538666 -3.77083653102375 0.000193961053164611 USP45 other 0.860126857793888 1 1 0.903777127580344 -3.77083653102375 4.80929028528643e-15 189.442160562515 23.30322022344 8.12944128519889 9.80527796909269e-15 -112.466836212631 71.8778920155711 -1.56469302394493 0.118652599004261 METTL8 other 6.61662157449707e-11 1 1.40911649693831e-10 8.12944128519889 -1.56469302394493 0.00206852442529136 39.5183231050433 13.8892252580852 2.84525035563369 0.00472833144343854 -62.8512054405652 39.6458453636552 -1.58531631408176 0.113897831175893 TTC21B other 1 1 1 2.84525035563369 -1.58531631408176 0.719227245650138 -3.06984295400611 41.5479485024843 -0.0738867516845639 0.941147098503717 -87.9059352976621 108.603579389401 -0.80942024003162 0.41888058781192 NMI other 1 1 1 -0.0738867516845639 -0.80942024003162 0.797719993846799 14.2869703227073 21.2665926374824 0.671803450898218 0.502198126583727 8.24605937067381 55.589461455811 0.148338536742773 0.882169917534165 TNFAIP6 other 1 1 1 0.671803450898218 0.148338536742773 0.00273719333848983 32.8874624246915 10.3359000145639 3.18186731473321 0.00160683459248193 -22.0620292815625 27.1335413504076 -0.813090668728027 0.416770608762762 ACVR1C other 1 1 1 3.18186731473321 -0.813090668728027 1.4030379024154e-06 136.078949047662 33.9274903307828 4.01087577421535 7.53545787196044e-05 -245.890090534941 92.924437466402 -2.64612944925112 0.0085442206549592 BAZ2B other 0.0143727202723433 1 0.791449140292005 4.01087577421535 -2.64612944925112 0.509630275860074 40.1288769696317 34.5250455626735 1.16231206405754 0.245974844367627 19.5256817001274 50.1704144501285 0.389187171645486 0.697396547622289 SLC36A1 other 1 1 1 1.16231206405754 0.389187171645486 0.000771730211675907 170.39198874379 49.0124804048361 3.47650205287258 0.000578178807322396 -256.295944539711 165.404514795304 -1.54950996867824 0.122247573364882 LPGAT1 other 1 1 1 3.47650205287258 -1.54950996867824 0.278094529550084 5.99407306472873 4.33136051117065 1.38387766367401 0.16736340600423 -11.0155246220892 13.8735514762175 -0.793994576008343 0.427788827701743 BATF3 other 1 1 1 1.38387766367401 -0.793994576008343 0.319252812058953 101.259626987825 94.6323187304974 1.07003218716643 0.285416320311081 -337.988010986722 321.129933020446 -1.05249612768176 0.293371075109581 G0S2 other 1 1 1 1.07003218716643 -1.05249612768176 0.739234524603795 -14.3564621367957 18.6651551045774 -0.769158469691738 0.44237014103396 -9.78232407645484 43.9873711539546 -0.222389377219588 0.824153543166355 KCNJ2 other 1 1 1 -0.769158469691738 -0.222389377219588 0.00115091481086011 50.3143523091059 32.7324038052889 1.5371419895833 0.125249798375767 -155.528279473671 59.0598427561165 -2.63340151642317 0.00886524596129958 EXOSC9 essential 1 1 1 1.5371419895833 -2.63340151642317 2.60941736262434e-10 85.7597468070808 18.4776408132388 4.64127145201546 5.07019804865945e-06 -107.671115281201 33.8374340534588 -3.18201182486516 0.00160698475260596 PLA2G12A other 3.22576174367621e-06 1 0.0580537676571507 4.64127145201546 -3.18201182486516 0.00246119635582638 0.673099272998601 7.15683532440497 0.0940498478012087 0.925128603867012 -62.3737843480889 18.6877670629528 -3.33767989176945 0.000944713713571444 B9D2 other 1 1 1 0.0940498478012087 -3.33767989176945 3.39354841253903e-10 116.362543634062 23.2058589448424 5.01436055052485 8.83189555945889e-07 -209.366835156626 67.5324061467144 -3.10024249249725 0.00210547178575167 COQ8B other 4.17677938615304e-06 1 0.0105541151935534 5.01436055052485 -3.10024249249725 0.0108637701453984 102.871907220564 33.9916519888947 3.02638739812273 0.00267578255185063 -8.18126148032387 115.436736325756 -0.0708722521159711 0.943543698566024 PFKFB2 other 1 1 1 3.02638739812273 -0.0708722521159711 7.62329823716395e-17 331.350110805779 84.1052260399592 3.93970893851889 0.000100318968968476 -951.433658363621 209.534685477721 -4.54069767110126 7.96656867152215e-06 RAB38 other 1.07221689705711e-12 0.117538754179638 1 3.93970893851889 -4.54069767110126 2.52713657935616e-11 371.173512263694 51.173489728007 7.25323823402556 3.10556054277138e-12 275.613081749551 262.061720169683 1.05171057249832 0.293728383908133 AGO2 other 3.21982471575768e-07 1 4.32977250873185e-08 7.25323823402556 1.05171057249832 9.06496110284338e-07 202.124142710062 54.2291264731909 3.72722475642284 0.000228858223525149 -337.273273528925 102.880260951349 -3.27830888462091 0.0011591707190044 CKS2 other 0.00941758808974399 1 1 3.72722475642284 -3.27830888462091 1.15587016208608e-05 83.1077373131345 93.8999387693592 0.885067002197595 0.376785049140114 -625.77717796717 163.795196452633 -3.82048553022211 0.000159991778158669 ACSL3 other 0.10970363708359 1 1 0.885067002197595 -3.82048553022211 0.00220650029857919 934.09910811795 315.478970139501 2.9608918391768 0.0032990203646196 -191.040305333087 554.430542576334 -0.344570312532493 0.730645910145741 CHPF other 1 1 1 2.9608918391768 -0.344570312532493 7.28939096336778e-13 193.746003961616 54.0121187144815 3.58708394658233 0.000386660392630319 -426.18534556461 94.8050900287725 -4.49538464058488 9.72037659541891e-06 DNPEP other 9.63220121899418e-09 0.143142265744139 1 3.58708394658233 -4.49538464058488 0.00275505840907723 245.444413373627 71.4338994161354 3.43596549229099 0.000668864646453576 150.116864265829 125.526761304197 1.19589530316998 0.232628377313572 OBSL1 other 1 1 1 3.43596549229099 1.19589530316998 0.69829714003965 -0.926081200353038 2.03342268488648 -0.455429757539436 0.64910992195221 1.49689903543059 3.53365750388039 0.423611805554672 0.672134421341315 FAM124B other 1 1 1 -0.455429757539436 0.423611805554672 0.000540264853845903 111.925244090379 55.6116556445955 2.01262204466046 0.0449944303311945 -335.675278145683 148.867771497774 -2.25485526362368 0.0248201701661265 SLC12A4 other 1 1 1 2.01262204466046 -2.25485526362368 0.128601513739964 31.8621162213218 17.4193115655077 1.82912603069874 0.0683141246648221 -2.84710918322525 46.6300465923019 -0.0610573952052467 0.951351734667504 ENKD1 other 1 1 1 1.82912603069874 -0.0610573952052467 0.703168507402412 18.3271996413547 23.9456634305301 0.765366125458358 0.444619438484805 58.0529411925502 114.276652832479 0.508003513873052 0.611801961036134 CTCFL other 1 1 1 0.765366125458358 0.508003513873052 0.00364850844195909 239.889407107822 73.9276238996791 3.24492245866519 0.00129945902139921 580.036747267878 351.529190772731 1.65003863830722 0.0999192690443133 FAM210B other 1 1 1 3.24492245866519 1.65003863830722 0.103311197425308 3979.4004197672 4135.29371804373 0.962301759220556 0.336624634632701 -29725.5476522524 18489.2843569253 -1.60771758811305 0.108883219031495 PI3 other 1 1 1 0.962301759220556 -1.60771758811305 2.24771435342323e-19 54.3257688667068 6.11523906815374 8.88367049288693 4.81903925425359e-17 -67.6930067980381 29.0782379794464 -2.32796109743259 0.0205391496326209 FAM209A other 3.24412612629575e-15 1 7.04109825438991e-13 8.88367049288693 -2.32796109743259 9.75295066056235e-10 84.724539038871 15.3528429904433 5.5184918579321 7.07015116560215e-08 -159.934679959673 69.7975228109911 -2.29140911480153 0.0225891536478936 SNX21 other 1.1793267938752e-05 1 0.000885677836514981 5.5184918579321 -2.29140911480153 0.135106607043321 -1005.26417913838 1787.29537303751 -0.562449942132358 0.574203292758435 14056.9885713329 8142.478990446 1.72637701464464 0.0852447637106225 SLPI other 1 1 1 -0.562449942132358 1.72637701464464 0.695092860372709 1.41623987155073 1.98895394928249 0.712052620454904 0.476950994516139 -2.58647160300213 9.0422378924522 -0.286043304076431 0.775030038667347 WFDC3 other 1 1 1 0.712052620454904 -0.286043304076431 3.1376178771114e-13 255.395807485359 36.9951689858733 6.90349076612902 2.74827699764976e-11 -342.17834125794 165.077786953843 -2.07283092154377 0.0389907006968543 TTPAL other 4.17585563264756e-09 1 3.77228500697407e-07 6.90349076612902 -2.07283092154377 0.015959544811151 -88.8247478007965 31.1909993560593 -2.84776857537721 0.00468743669296816 -24.490689509821 143.782459708386 -0.17033155198132 0.864857038520744 PREX1 other 1 1 1 -2.84776857537721 -0.17033155198132 0.28698126073331 -15.1385518081475 19.0988387188433 -0.792642528218823 0.428575213799714 -130.209860657795 85.3470981781312 -1.52565070678829 0.128087687545763 KCNS1 other 1 1 1 -0.792642528218823 -1.52565070678829 0.0167586869941628 12.0877995593891 4.30633326627746 2.80698190594019 0.00530745619743861 1.08677764086479 19.5775723474687 0.0555113586902571 0.955765723407797 SLC12A5 other 1 1 1 2.80698190594019 0.0555113586902571 0.0202758849790988 19.8848792791584 9.13133345432621 2.17765339297049 0.0301711976799638 -59.4758293523959 46.4703322936183 -1.27986666797654 0.201530841710073 ARHGAP40 other 1 1 1 2.17765339297049 -1.27986666797654 1.13117404929748e-05 1527.63951043225 421.86753174078 3.62113553543371 0.000340907316876134 -4301.14628335203 1921.92491838254 -2.23793668639865 0.0259128794303098 SDC4 other 0.107383724380005 1 1 3.62113553543371 -2.23793668639865 2.88172787689902e-09 392.42165150464 66.1183951955858 5.93513575675592 7.6317313973698e-09 -332.37286624287 305.8781258686 -1.0866186174609 0.278023219005515 NCOA3 other 3.42579810005755e-05 1 9.89988196866811e-05 5.93513575675592 -1.0866186174609 2.97381005381523e-10 488.49930323737 76.1023467992563 6.41897817587596 4.94596745610479e-10 -278.138544191778 345.978610606353 -0.803918322304143 0.422040936836909 PIGT other 3.66908684439723e-06 1 6.63056397165408e-06 6.41897817587596 -0.803918322304143 0.606228227736397 12.8999453671459 13.5898556342897 0.949233436637621 0.343218221862757 -4.49654509960035 61.9120463549007 -0.0726279514946838 0.942147556881043 MATN4 other 1 1 1 0.949233436637621 -0.0726279514946838 0.14456540771208 44.5315813449834 22.6602054106782 1.96518877644414 0.0502570818942103 31.3128567267839 103.018457561122 0.303953849320696 0.76136059832532 NCOA5 other 1 1 1 1.96518877644414 0.303953849320696 7.74132902146237e-17 293.786206472816 34.5722179844008 8.49775408119242 7.43676515691829e-16 -217.668484207526 161.728075483615 -1.34589176033062 0.179290166874687 VAPB other 1.08866310028825e-12 1 1.07840531540472e-11 8.49775408119242 -1.34589176033062 0.0314009726921741 15.7879737542228 6.72297264909129 2.34836203838443 0.0194644625549805 -19.3100116249133 31.0364580853341 -0.62217188481433 0.534271901264136 PARD6B other 1 1 1 2.34836203838443 -0.62217188481433 0.00302779502397308 479.497991436229 191.876665002688 2.49899064813072 0.0129556313591132 -1560.15018041545 900.828743019157 -1.73190541765637 0.0842540651033021 ATP5E essential 1 1 1 2.49899064813072 -1.73190541765637 0.0243080552410317 126.19838739488 46.2768038432732 2.72703334962975 0.00674533746050934 70.8788017640598 210.857875545657 0.336144910787136 0.736983284176594 CHD6 other 1 1 1 2.72703334962975 0.336144910787136 1.54871919879667e-09 227.155646428241 37.5541776857623 6.04874505118936 4.09652268488676e-09 -195.699120280525 171.11367828042 -1.14367899893902 0.253616985184196 PLCG1 other 1.85691431935721e-05 1 5.35948062863735e-05 6.04874505118936 -1.14367899893902 0.187067351269511 32.4471611567382 19.299402559628 1.68125210386635 0.09369269200305 -25.148148881998 86.1167214911564 -0.292023993093845 0.770458102251061 TOX2 other 1 1 1 1.68125210386635 -0.292023993093845 0.00605906132631803 190.612666374142 63.9668089516603 2.97986830198436 0.00310592813692902 -135.459406172296 287.546973926333 -0.471086182277126 0.637902190671801 SRSF6 other 1 1 1 2.97986830198436 -0.471086182277126 1.16664747298089e-07 272.551732424146 49.2253814658945 5.53681300800039 6.42757729850244e-08 -76.8647796337764 227.247910759732 -0.338241963927427 0.735402660186715 ARFGEF2 other 0.00128261223179519 1 0.000806211020551161 5.53681300800039 -0.338241963927427 0.0006299045392568 268.512449267787 87.8551427319941 3.05630883882228 0.00242949825582678 -648.229670211357 405.581369626892 -1.598272797411 0.110969184505022 ZNFX1 other 1 1 1 3.05630883882228 -1.598272797411 0.0153489701164391 -9.87809716445501 3.39917215573493 -2.90603026616028 0.00391566900648182 -8.40175525858899 15.9585428499788 -0.526473835209845 0.598923741762406 ZNF831 other 1 1 1 -2.90603026616028 -0.526473835209845 0.895023699854567 -8.68661148915995 23.4292873287065 -0.370758673419689 0.711062596705303 -40.3709297017278 109.996572297406 -0.367019888515924 0.713846766679708 EDN3 other 1 1 1 -0.370758673419689 -0.367019888515924 4.80224823823507e-13 629.657239512223 85.0685972107837 7.40175881767572 1.19587060240239e-12 -335.724754199404 392.717342389832 -0.854876314237596 0.393259194048477 CSE1L essential 6.36826138872353e-09 1 1.67720851986935e-08 7.40175881767572 -0.854876314237596 5.0990810338818e-26 721.609982445601 70.5009453868869 10.2354653329205 1.85868997957587e-21 -1094.67075093819 325.466092260884 -3.36339415062855 0.000863393500706412 TMEM189-UBE2V1 other 7.62822522668718e-22 1 2.77632522249248e-17 10.2354653329205 -3.36339415062855 3.59876471758492e-19 381.892284885477 43.820393199393 8.71494427600816 1.59797144760523e-16 -516.97916800117 204.990835770815 -2.52196234069295 0.0121551674361574 RAB22A other 5.18761934039866e-15 1 2.32776500772654e-12 8.71494427600816 -2.52196234069295 0.867857860455083 -8.64230032846231 21.1715690344469 -0.408203110237176 0.683397563956233 22.9415970602234 97.7380913526674 0.234725241128798 0.814572116097592 PTGIS other 1 1 1 -0.408203110237176 0.234725241128798 7.18437086220066e-19 613.841600024967 66.3820546329382 9.24710154603115 3.35774089358642e-18 -263.598221154222 306.451322022264 -0.860163432856955 0.390342926718298 STAU1 other 1.03289699885859e-14 1 4.94091572491241e-14 9.24710154603115 -0.860163432856955 0.575292044057361 -8.00606900660046 13.6588424996263 -0.586145495624503 0.558190946248603 46.0783257134123 64.1259734208045 0.718559473725868 0.472936720066466 CDH26 other 1 1 1 -0.586145495624503 0.718559473725868 0.73641478637895 3.48132633237889 6.14843682788219 0.566213239207668 0.571645693056614 -11.0588180037918 28.3841258709692 -0.389612773494025 0.697082075134851 SNAI1 other 1 1 1 0.566213239207668 -0.389612773494025 1.46350849443156e-18 61.2137155251107 6.56428820689987 9.32526324191062 1.88339105111377e-18 -8.6088358702691 30.3038947839596 -0.284083479422121 0.776530135848417 MOCS3 essential 2.09735402336988e-14 1 2.77517671381614e-14 9.32526324191062 -0.284083479422121 1.27019651748584e-14 299.0198508928 38.452025625099 7.77643949913577 1.03209489423304e-13 -246.994888574854 179.877730309344 -1.37312655741255 0.170674385123919 STX16 other 1.7354695018409e-10 1 1.46887745347246e-09 7.77643949913577 -1.37312655741255 6.63170477362216e-06 918.070279481224 189.557622391857 4.84322533642764 1.99297231684446e-06 -11.6157528632495 886.746389153203 -0.0130992953626143 0.989556736278027 PMEPA1 other 0.0643076411898141 1 0.023357635553417 4.84322533642764 -0.0130992953626143 3.08990029208324e-05 158.273750321831 44.2267691632496 3.5786866939706 0.000398798134881547 -408.889569566135 204.171924984772 -2.00267284347067 0.0460556954728783 RNF114 other 0.282046098661358 1 1 3.5786866939706 -2.00267284347067 1.60742211858916e-21 367.323011866774 37.466600911027 9.80401218512098 5.15343549053859e-20 -257.004492365788 172.963754200637 -1.48588641333296 0.138293677450242 DDX27 essential 2.35664156806356e-17 1 7.65491307764603e-16 9.80401218512098 -1.48588641333296 0.000135474018051188 -1.16690437190253 21.5282070749972 -0.0542035092768024 0.956806848640106 418.539506348756 100.708479288862 4.15595101131713 4.162581848333e-05 C20orf85 other 1 0.602117464361369 1 -0.0542035092768024 4.15595101131713 0.499671144038038 9.64326558635583 41.0860169390978 0.234709185868519 0.814584567511077 -202.246972139219 189.672710150917 -1.0662945237525 0.287094351515389 BCAS4 other 1 1 1 0.234709185868519 -1.0662945237525 0.283847020630426 4.76528456615905 3.74074248101408 1.27388736068975 0.203630675256882 20.712079164877 16.6917331980787 1.24085850876535 0.215569793589841 KCNK15 other 1 1 1 1.27388736068975 1.24085850876535 0.0018415462117238 2.12234309971209 0.598982174179518 3.54324918369943 0.000454068973599618 0.877639532139297 2.77282595861879 0.316514467635925 0.751818417154196 TP53TG5 other 1 1 1 3.54324918369943 0.316514467635925 0.603775674230927 -5.14552882420636 11.6944954946047 -0.439995793455158 0.660238112542128 43.6702622320753 55.8100135987064 0.782480766732648 0.434512536637159 PCK1 other 1 1 1 -0.439995793455158 0.782480766732648 0.0622670061065546 -18.5980014815989 8.31659222245196 -2.23625266024114 0.0260262858489171 -49.8453191588236 39.6895381458804 -1.2558805541051 0.210078321908925 ZBP1 other 1 1 1 -2.23625266024114 -1.2558805541051 0.00731271541865593 3.93576789514956 1.32510457877973 2.97015643759524 0.00320160492538715 -2.03171054105522 6.02422737742444 -0.337256616287257 0.736144561726429 NEURL2 other 1 1 1 2.97015643759524 -0.337256616287257 1.34433647957325e-14 43.5478937509811 5.3444150327235 8.14829938998754 8.47128484042507e-15 -39.6522650616732 30.8653120957816 -1.28468699550563 0.199833771882344 FASTKD3 other 1.83569146285727e-10 1 1.2177471958111e-10 8.14829938998754 -1.28468699550563 1.6240527498273e-06 251.171382007498 53.863055009591 4.66314771716484 4.58010850492709e-06 -193.332254370755 160.40030313666 -1.20531102865832 0.228973797720901 PEPD other 0.0165366382202063 1 0.0525613252025432 4.66314771716484 -1.20531102865832 9.29075561079619e-07 164.461171189553 30.5375947655854 5.38553125915775 1.4014176491361e-07 26.0017547439298 126.364272572819 0.205768246154751 0.837102788650797 STAMBP other 0.00964473339956752 1 0.00173467476610067 5.38553125915775 0.205768246154751 0.0886669403608404 -154.342176981052 72.1423029927751 -2.1394129460562 0.0331585238775894 -204.90163423251 299.533995105599 -0.68406804429752 0.494427276919041 NAGK other 1 1 1 -2.1394129460562 -0.68406804429752 0.46637793673301 7.09696929334107 6.36963712286483 1.11418737935092 0.26603495219403 -12.359746181415 26.5352092769771 -0.465786647936435 0.641685089890199 MCEE other 1 1 1 1.11418737935092 -0.465786647936435 0.131054321877562 31.4221925539529 16.4024043487038 1.91570649558069 0.0562933957586549 52.3867186652996 68.3306165866321 0.766665387818969 0.44384570413883 PAIP2B other 1 1 1 1.91570649558069 0.766665387818969 0.00202295906361027 47.1048467680971 13.2562906073792 3.55339575475781 0.000437550759112941 9.04571758756415 56.9992629209003 0.15869885195037 0.874006249619652 SNRNP27 essential 1 1 1 3.55339575475781 0.15869885195037 8.74886354529418e-08 162.350371249176 27.7579780198272 5.84878232604735 1.2228772243007e-08 48.9160778616544 115.63669038819 0.423015201295056 0.672568304956205 MPHOSPH10 essential 0.000969024126276784 1 0.000157555501578902 5.84878232604735 0.423015201295056 0.477142298767236 -8.54782549304947 14.6996756874888 -0.581497556461378 0.561319722927939 16.7433377874768 28.1411608338425 0.594976798801465 0.552284781603247 ATP8A1 other 1 1 1 -0.581497556461378 0.594976798801465 4.8297318856098e-13 1041.29467434647 141.045451044306 7.38268881865156 1.35174954164051e-12 -563.705553890454 262.783506477008 -2.14513293260959 0.0326946250942104 USP22 other 6.40422448031859e-09 1 1.89434180765502e-08 7.38268881865156 -2.14513293260959 0.176248737475195 40.868464543409 24.602923411089 1.66112229268611 0.0976682728254113 -24.0809565639779 56.628138647807 -0.425247185215586 0.670942311948812 HIF3A other 1 1 1 1.66112229268611 -0.425247185215586 1.73323758703815e-05 32.1042511090849 11.8666840744902 2.7054104505992 0.00718976832443431 -91.8727617172236 29.5259046888934 -3.11159853305977 0.00202953461398405 ZNF576 other 0.161936387756974 1 1 2.7054104505992 -3.11159853305977 1.13517168228498e-28 84.11767954667 6.83975183351303 12.2983525709975 1.02673901462138e-28 -17.3843686215244 28.8048011139741 -0.603523299908872 0.546589511094993 ZNF45 other 1.71036317369878e-24 1 1.55663902006747e-24 12.2983525709975 -0.603523299908872 0.173144763589069 1366.57325176211 1101.69658765824 1.2404261455206 0.215729372468547 -2894.13595727892 2756.40481224091 -1.04996767689069 0.294527752608393 LYPD3 other 1 1 1 1.2404261455206 -1.04996767689069 0.875533421482696 -0.680632426431661 2.21019158473992 -0.307951777181232 0.758321909402768 -3.04378867441898 6.34716724821907 -0.479550727968138 0.631878611823535 CEACAM8 other 1 1 1 -0.307951777181232 -0.479550727968138 0.933150294860011 52.7410507688234 148.09142062323 0.356138461950512 0.721973031489045 16.7630138222295 331.418213755486 0.0505796396410395 0.959692242192099 F13A1 other 1 1 1 0.356138461950512 0.0505796396410395 0.910116330150795 1.22750931139267 5.60251595721269 0.219099654649332 0.826712537585078 -3.44203011572762 12.9712193896779 -0.265359023876096 0.790904296847866 GRM4 other 1 1 1 0.219099654649332 -0.265359023876096 0.0644225625633024 47.4520807867554 22.9618866783302 2.06655844319349 0.0395824734014051 -44.9052716091618 79.7951968481861 -0.562756574115558 0.573995931572509 TRERF1 other 1 1 1 2.06655844319349 -0.562756574115558 0.996851202749027 -0.372164535342569 5.18102429103542 -0.0718322313189141 0.942780436634785 0.0540044486181406 11.9953612369014 0.00450211107040331 0.996410661318127 PACSIN1 other 1 1 1 -0.0718322313189141 0.00450211107040331 0.938516408038788 -4.64687983769675 23.6365814966012 -0.19659695029778 0.844267755551072 -18.057108409662 51.629102796435 -0.349746701600803 0.72675886730495 BTN2A2 other 1 1 1 -0.19659695029778 -0.349746701600803 1.07612334654608e-10 86.8577684647701 13.8681355544527 6.26311793129844 1.22327328451423e-09 -11.0212654758389 32.7680940004038 -0.33634136534469 0.736835292472774 SIRT5 other 1.34375522283209e-06 1 1.6245069218349e-05 6.26311793129844 -0.33634136534469 2.47625374901425e-09 106.154704876478 20.5790209347281 5.1583943285337 4.39109121103588e-07 -69.9078413868795 45.0448033701499 -1.55196240535053 0.121665845972848 MRS2 other 2.95169446882498e-05 1 0.00532112432953328 5.1583943285337 -1.55196240535053 2.21741560236161e-16 375.217449896415 49.3665528806429 7.60064108190024 3.33552616430171e-13 -144.437600299421 109.522523748526 -1.31879357191461 0.188187065068959 WRNIP1 other 3.10571229266767e-12 1 4.70976294399401e-09 7.60064108190024 -1.31879357191461 1.13950840010644e-25 274.684780618476 24.8434131946683 11.056644208511 2.90375185285196e-24 -94.3149872622759 86.2424995894273 -1.09360219974234 0.274957193266027 RRP36 other 1.70310925479908e-21 1 4.36840428743049e-20 11.056644208511 -1.09360219974234 0.0133466141318662 8.17023099695086 2.87491439019806 2.841904101495 0.00477232988013867 2.06682414841595 6.27964118262318 0.329130930941596 0.742272033129484 BTN2A3P other 1 1 1 2.841904101495 0.329130930941596 9.41296823305354e-09 304.763596852841 60.0526736078591 5.07493802595587 6.5965103364041e-07 -214.592751855893 139.227807592495 -1.54130669416258 0.124233524282527 SNRPC essential 0.000109425755709247 1 0.00792636682022316 5.07493802595587 -1.54130669416258 0.00879911341527349 -216.443564984988 77.2110159546434 -2.80327311211829 0.00536934286036152 -401.743994460423 171.29705914419 -2.34530584744163 0.0196258233117547 SERPINB6 other 1 1 1 -2.80327311211829 -2.34530584744163 2.88641055652656e-25 542.521968748437 51.2812242934177 10.5793489961213 1.33306892406318e-22 -218.416022687433 141.634167151453 -1.5421139339484 0.124043542266593 XPO5 essential 4.30767911456025e-21 1 1.99747047581627e-18 10.5793489961213 -1.5421139339484 0.00108434361873093 81.0158743176244 22.9646432923632 3.52785250291982 0.000480860333244676 -8.29214172134019 63.4262962996686 -0.130736653487735 0.896066562317843 ABCC10 other 1 1 1 3.52785250291982 -0.130736653487735 6.46949708135779e-16 265.212289017293 30.766745933748 8.62009552743704 3.16964115780658e-16 29.1885662316493 106.917980327742 0.272999603454685 0.785030166898215 PEX6 other 9.00812773608259e-12 1 4.6064394946403e-12 8.62009552743704 0.272999603454685 7.07630734007544e-06 132.479153158485 33.4015910484579 3.96625277419536 9.02520902551392e-05 -82.9483002848865 74.1033419466831 -1.11935977657482 0.263831449523941 NQO2 other 0.0684561972078898 1 0.939975520007275 3.96625277419536 -1.11935977657482 2.26172315035378e-10 198.714975025045 34.9085612732684 5.69244242034154 2.8470297671905e-08 -196.009938389711 95.9003935311884 -2.04389086605745 0.0417878778181411 PRICKLE4 other 2.8020488109733e-06 1 0.00036211371608896 5.69244242034154 -2.04389086605745 0.00215208791736729 46.2800554528406 14.7261857828716 3.14270484803132 0.0018316040021053 -23.1189204977952 40.5277149568071 -0.570447174789756 0.568777278791876 OARD1 other 1 1 1 3.14270484803132 -0.570447174789756 0.242935502768761 -46.2948692277383 31.0623484411541 -1.49038535561602 0.13711413435203 -103.614584299468 85.4862231180293 -1.21206178633497 0.226388513588144 UNC5CL other 1 1 1 -1.49038535561602 -1.21206178633497 2.9902095627967e-09 83.4554608215808 13.8752056596986 6.01471883504994 4.93396778146873e-09 -18.2457179021481 38.5735160509036 -0.473011531488863 0.636528441173375 AARS2 essential 3.55087385582108e-05 1 6.43932135159484e-05 6.01471883504994 -0.473011531488863 6.99462847670908e-09 27.0872454830346 4.74036779130889 5.714165371872 2.52374480965466e-08 -3.22898316737193 10.7461461217091 -0.300478248741549 0.764007502679575 ZNF391 other 8.17742015212059e-05 1 0.000321777463230969 5.714165371872 -0.300478248741549 0.000573500781028662 288.282623267527 109.374612145612 2.63573618787998 0.00880580218864062 -427.823378783301 253.229459877788 -1.68946922285335 0.0921065847261581 RPS10 other 1 1 1 2.63573618787998 -1.68946922285335 0.0479447293417015 30.770131023497 18.7152883822153 1.64411738654998 0.101140162832025 -51.1054486444656 43.5941813845484 -1.17229976619264 0.24195420122421 MOCS1 other 1 1 1 1.64411738654998 -1.17229976619264 0.376499749952214 13.1802792570838 11.5571832361953 1.14044045055937 0.254955672462181 -8.5261318888983 26.2257569240846 -0.325105273932753 0.745313845681507 HIST1H2BJ other 1 1 1 1.14044045055937 -0.325105273932753 1.22044636577072e-20 132.340830986992 14.5146451984679 9.117744814111 8.91471626110271e-18 -75.4829083696367 39.8744644788483 -1.89301372084074 0.0592638437985015 MED20 essential 1.77941080129371e-16 1 1.30769972834116e-13 9.117744814111 -1.89301372084074 3.90568052783893e-18 99.3925612138522 10.7298481173905 9.26318435512251 3.02205193501829e-18 4.21380593230087 37.28745615169 0.113008672813683 0.91009476253449 TBCC essential 5.57496838543728e-14 1 4.44755383276642e-14 9.26318435512251 0.113008672813683 0.63798810525324 -9.00447784036769 27.815112744921 -0.323726095340451 0.746357545565257 -61.1579166934086 64.4873397427988 -0.948370904077152 0.343658549378409 SPDEF other 1 1 1 -0.323726095340451 -0.948370904077152 0.481235256048123 -6.19308178409163 7.7161156483398 -0.802616506327783 0.422792113777963 9.88749758286097 17.8292136563244 0.554567227329943 0.579578090127163 TCP11 other 1 1 1 -0.802616506327783 0.554567227329943 1.16020345251309e-05 50.2515396808964 12.2708130563267 4.09520864267322 5.35557744643342e-05 -43.4762212059102 34.1201211627781 -1.27421063361694 0.203519173345545 MAD2L1BP other 0.110080103574442 1 0.569619217202659 4.09520864267322 -1.27421063361694 0.503536264961575 26.1535362425729 26.1639968102383 0.99960019228938 0.318264041893734 -19.6176342950092 72.0055430843122 -0.272446168096234 0.785455797301096 APOBEC2 other 1 1 1 0.99960019228938 -0.272446168096234 3.60359911545279e-19 499.509018872513 52.8290636672249 9.45519349006385 7.26439633385497e-19 -59.7521898418847 183.587071641193 -0.325470575393598 0.745038322571854 KLHDC3 other 5.19422776501365e-15 1 1.07258811869369e-14 9.45519349006385 -0.325470575393598 0.0372852994434024 3.77632599218358 23.6218799336395 0.159865599299985 0.873088124451793 -154.819129960917 64.5580645324519 -2.39813772426671 0.0170528691262669 TREM1 other 1 1 1 0.159865599299985 -2.39813772426671 2.91987616639902e-20 326.590320626661 33.616890192896 9.71506640717401 1.0290325034755e-19 -61.5231138992855 116.822559397853 -0.526637271229109 0.598811493502409 MEA1 other 4.24462398309425e-16 1 1.52543778315208e-15 9.71506640717401 -0.526637271229109 0.610236184979161 8.86761551002207 13.5367480556298 0.655077236687884 0.512894593832868 -19.7819479259108 36.7489281892791 -0.538299996778732 0.590748906750233 KLHL31 other 1 1 1 0.655077236687884 -0.538299996778732 0.000182719200484767 173.781559932603 42.0255498774478 4.13514065703778 4.57212736890435e-05 48.2551988296929 118.639894550786 0.40673669689614 0.684482054085549 COL21A1 other 1 1 0.489674841209656 4.13514065703778 0.40673669689614 0.054989733437816 499.743852854602 380.071268308464 1.31486880099816 0.189495502206596 -1262.23306131724 882.28224588147 -1.43064542804686 0.153507614099473 CDKN1A other 1 1 1 1.31486880099816 -1.43064542804686 0.17408488963336 261.070805682917 208.295203186007 1.25336926482067 0.210992083930147 -366.814822922342 469.931598920781 -0.780570669784175 0.435635694356809 SOX4 other 1 1 1 1.25336926482067 -0.780570669784175 1.15179415991117e-06 684.917519776279 147.140810843546 4.654843995012 4.75637732185536e-06 -280.226800519171 340.408260163513 -0.823207992616175 0.41100277952617 GLO1 other 0.0118749977886841 1 0.0545175968631062 4.654843995012 -0.823207992616175 0.105627937184416 -2.50461017788597 10.0391172500023 -0.249485100683071 0.803145632466989 43.9091617483182 23.3020355876787 1.88434875498756 0.0604240616348123 CPNE5 other 1 1 1 -0.249485100683071 1.88434875498756 0.00161750962740207 241.025089072194 77.4174151083187 3.11331873758589 0.00201755351245904 -62.3987831025126 173.154538158864 -0.36036469945283 0.718812910578557 RREB1 other 1 1 1 3.11331873758589 -0.36036469945283 3.92534795424619e-15 950.050640899105 140.747125357225 6.75005360491603 6.98425276483129e-11 -615.992626666967 314.800015659516 -1.95677444734697 0.0512460414759941 SSR1 other 5.40481159820157e-11 1 9.51464754152966e-07 6.75005360491603 -1.95677444734697 2.2277449542867e-16 244.309113428605 31.1396484243537 7.84559639528671 6.60954227588549e-14 -47.0046960312198 69.6611767200964 -0.674761728761602 0.50031743042358 RIOK1 essential 3.11995680847852e-12 1 9.42652919386789e-10 7.84559639528671 -0.674761728761602 0.0309329328421098 63.0674986975263 34.8434919537303 1.810022335915 0.0712362140936248 196.116983965749 77.9772914305985 2.5150525283415 0.012394288433136 NRN1 other 1 1 1 1.810022335915 2.5150525283415 0.00474777455045062 30.861781961627 13.8478750790702 2.22862943125995 0.0265350615627117 -39.0766883805419 30.97264885999 -1.26165148344869 0.207995972771964 SLC35B3 other 1 1 1 2.22862943125995 -1.26165148344869 2.41003857704004e-13 60.5792511626809 8.67263332398292 6.98510462735207 1.6803728580905e-11 -12.5639828607852 19.4214523146629 -0.646912633371894 0.518156626395806 RPP40 essential 3.21667848877534e-09 1 2.31437753744805e-07 6.98510462735207 -0.646912633371894 3.21914834486949e-09 238.356311696112 43.3569587719221 5.49753300156448 7.88203383093572e-08 -92.9767180176685 102.617421442883 -0.906051981333595 0.365590046733431 ATXN1 other 3.81726610734624e-05 1 0.000985291490873537 5.49753300156448 -0.906051981333595 1.31351205300563e-11 515.848625968626 76.677801994315 6.72748321615782 7.96620295202401e-11 -18.9810999810997 180.946101691833 -0.104899192652551 0.916521519063165 NUP153 essential 1.68405380315852e-07 1 1.08404089771143e-06 6.72748321615782 -0.104899192652551 2.05651098666107e-06 884.09789014254 188.611601496707 4.68739930697199 4.10056368277359e-06 -121.401642983038 445.090145218468 -0.272757427427311 0.785215615521527 DEK other 0.0207378567894902 1 0.0472056891160895 4.68739930697199 -0.272757427427311 4.11626442634113e-10 81.8958801885971 14.3021414671454 5.72612712416017 2.37342963021926e-08 -29.0558405074696 31.9886771853764 -0.908316412682187 0.36439676096983 EEF1E1 other 5.05147970400583e-06 1 0.000302825886519675 5.72612712416017 -0.908316412682187 0.000572374233809749 89.2435696827835 26.5237194741385 3.3646702442996 0.000859547596279658 -67.2721757988975 73.7490189334507 -0.912177229904607 0.362362104646078 RUNX2 other 1 1 1 3.3646702442996 -0.912177229904607 8.3909948276005e-19 916.992348428412 138.250923725579 6.63281172897329 1.40425665054684e-10 -847.944811715168 249.555609178103 -3.39781908532461 0.000765063830573077 LRRFIP1 other 1.20519858708826e-14 1 1.9023464844958e-06 6.63281172897329 -3.39781908532461 0.206382472780454 15.0089603930492 14.3100757871536 1.04883863763482 0.295043881775647 -21.0102655052951 25.8310005041016 -0.813374050376369 0.41660840432896 RAB17 other 1 1 1 1.04883863763482 -0.813374050376369 0.198412146735737 -32.4231786181264 53.5739429962971 -0.605204261712965 0.545474925233502 -209.291021751592 116.078289081208 -1.80301607999385 0.0723322344277971 CXCL6 other 1 1 1 -0.605204261712965 -1.80301607999385 0.00234685450940327 195.126730118477 126.02904378453 1.54826795680591 0.122552392671429 -655.526845459712 272.387200834142 -2.4065992948724 0.016671729513008 EREG other 1 1 1 1.54826795680591 -2.4065992948724 0.457780196022181 -20.5070080033664 20.5303822263388 -0.998861481354089 0.318623641763542 -73.4743974996337 72.4328405332202 -1.01437962336899 0.311175237259721 MYRF other 1 1 1 -0.998861481354089 -1.01437962336899 0.00102214574643862 54.5573146881522 42.6508631863471 1.27916085659941 0.201790935028616 596.36767794 159.429787820235 3.74062893825359 0.000218397488949411 SCGB2A1 other 1 1 1 1.27916085659941 3.74062893825359 3.23943689607372e-08 9740.86036446289 2020.09412648334 4.82198340996127 2.31663900693293e-06 -17521.449212332 7832.90839511153 -2.23690209670613 0.0260660623491295 AHNAK other 0.000366866228480348 1 0.0270583436009766 4.82198340996127 -2.23690209670613 3.66105095515115e-33 443.435586945015 39.8101869585974 11.1387466581402 1.42563562152929e-24 -174.274240527475 69.5524810255473 -2.50565095533347 0.0127188585621101 EMC3 essential 5.55564482444186e-29 1 2.14629442821235e-20 11.1387466581402 -2.50565095533347 7.16335017048177e-11 40.2226809852612 78.440887368706 0.512776975561192 0.608461116017686 -802.376644288875 145.469993643145 -5.51575362172077 7.17140747861454e-08 SH3TC1 other 9.00504749931263e-07 0.00108496223743959 1 0.512776975561192 -5.51575362172077 2.07426803844259e-08 676.573881931248 185.192768367274 3.65334936075618 0.000302494113886504 -1378.75517839239 491.43492441472 -2.80557019840303 0.00533116862708669 CNOT1 essential 0.000237275520917447 1 1 3.65334936075618 -2.80557019840303 0.000759105564122011 8.78323659493657 2.60817204196126 3.36758329344404 0.000851430477308221 -2.08920220416879 6.98128909670271 -0.299257368550392 0.764939166354216 LRRC29 other 1 1 1 3.36758329344404 -0.299257368550392 5.36607903008006e-10 82.1705929167916 19.4264114123293 4.22983901517912 3.05921717001909e-05 -141.907323857072 51.2506857035411 -2.76888634579316 0.00595387458030805 BBS2 other 6.55895839846686e-06 1 0.331955655118772 4.22983901517912 -2.76888634579316 0.0165455133922847 6.06214406649222 23.1007827932231 0.262421586348608 0.793165289289963 -148.918818807061 61.1338970355637 -2.43594513074194 0.0153982709013794 MT1G other 1 1 1 0.262421586348608 -2.43594513074194 0.00248582127705729 453.96895682623 1543.33486735164 0.294148059782541 0.76883547422631 -12118.7567212195 4084.28042099721 -2.96717058381133 0.00323200948039153 MT2A other 1 1 1 0.294148059782541 -2.96717058381133 3.32388046624557e-14 121.66513921844 19.9649042608667 6.09395054585441 3.17332510228308e-09 -141.163123905411 53.7801181360041 -2.62481989251911 0.00908685236888245 C16orf70 other 4.50452280785599e-10 1 4.16594119427722e-05 6.09395054585441 -2.62481989251911 6.36148935502416e-12 643.622771873761 138.775101288031 4.63788363978857 5.13690989338668e-06 -1153.64723994993 363.297320030286 -3.17549064180753 0.00164145414785038 GOT2 other 8.22540573604624e-08 1 0.0588124813693841 4.63788363978857 -3.17549064180753 2.89694743929291e-16 204.130270589205 33.9146539988842 6.01894008990688 4.80567076676675e-09 -286.233506591712 89.2733467413685 -3.2062593936458 0.00148054582264055 DOK4 other 4.051960383339e-12 1 6.27476432016735e-05 6.01894008990688 -3.2062593936458 0.0115067185704161 -4.17995999845298 1.48380160222217 -2.8170612514456 0.00515252284876651 -5.87285205014068 3.44872818887132 -1.70290371653288 0.0895725045847316 GPR18 other 1 1 1 -2.8170612514456 -1.70290371653288 0.00269742440889724 8.88347628240314 5.03293171439789 1.76506990090683 0.0785240301786141 -29.0872057782043 11.7049954041988 -2.48502496359547 0.0134746956728262 CLYBL other 1 1 1 1.76506990090683 -2.48502496359547 0.183965583554081 30.0689251841627 16.2971235227207 1.8450449333738 0.0659665692923652 16.1125735821327 37.8008677433279 0.426248775333383 0.67021678503512 TMTC4 other 1 1 1 1.8450449333738 0.426248775333383 1.02284156018779e-16 213.071334307046 26.2316674580751 8.12267594683364 1.0541414729512e-14 -125.005355417325 61.0303520183826 -2.04824896601732 0.0413669109903421 RAP2A other 1.43699010790782e-12 1 1.51459046833629e-10 8.12267594683364 -2.04824896601732 0.278155385767984 37.3413776316932 23.4031740292781 1.59556894227159 0.111600707798872 12.4726902674681 54.5642227243167 0.228587335157064 0.819339901301985 ABCC4 other 1 1 1 1.59556894227159 0.228587335157064 2.92400534682158e-21 885.098255719638 87.8546100987912 10.0745795209194 6.70451771665691e-21 -102.981348069787 206.779268400984 -0.498025497750028 0.618810308751373 EFNB2 other 4.27957422560806e-17 1 9.98973139781879e-17 10.0745795209194 -0.498025497750028 4.99955767149801e-05 -91.7450473124023 35.1829884187912 -2.6076536256767 0.00955482045376198 243.719853607809 81.9433383292848 2.97424853047156 0.0031661988679599 SOX21 other 0.446210522181198 1 1 -2.6076536256767 2.97424853047156 4.20001379914861e-24 1114.98826971259 106.377454528473 10.4814340092538 3.06503478416474e-22 -418.768864983141 247.400061638847 -1.6926789031866 0.0915084973048618 TM9SF2 other 6.23534048621603e-20 1 4.58774406493778e-18 10.4814340092538 -1.6926789031866 0.191394107962261 25.2607650053534 15.1940861597691 1.66253927611907 0.097383839137398 -22.6155583878033 36.6303293614672 -0.617399809994432 0.537410122296588 C17orf53 other 1 1 1 1.66253927611907 -0.617399809994432 3.22247884760543e-09 188.288210450101 220.32806390208 0.854581151013891 0.393424392718762 -1850.3733759704 329.740926270412 -5.61159755599448 4.35544598008757e-08 IRF1 other 3.82089316960576e-05 0.000659675848144064 1 0.854581151013891 -5.61159755599448 5.24443535578762e-07 57.5930025154355 11.7499556127678 4.90155064525123 1.52038641118775e-06 -47.6363970468134 36.1289216726474 -1.31851145402101 0.188284307278755 ATP5S other 0.00553655040510499 1 0.017952722743305 4.90155064525123 -1.31851145402101 0.25250823244529 5.57428429182853 7.79823461722264 0.714813616855994 0.475250296156116 37.8077572643555 23.3214455361685 1.62115839713797 0.105977877884786 BMP4 other 1 1 1 0.714813616855994 1.62115839713797 0.556192552718377 3.211878701362 3.04388705769594 1.05518984130549 0.292144588849419 4.4022337248848 9.28361090266004 0.474194122420989 0.635688975406193 PTGER2 other 1 1 1 1.05518984130549 0.474194122420989 1.19333478764907e-13 113.179823950033 22.9248071080889 4.93700223589223 1.27945019164503e-06 -109.042884004543 42.3992354106109 -2.57181250908251 0.0105677896017698 FAM193A other 1.60133595154628e-09 1 0.0151768381732934 4.93700223589223 -2.57181250908251 7.08618464101638e-17 23.1452085996376 4.77581782962842 4.84633405739399 1.96411739944976e-06 -33.1076412883046 8.83283438250436 -3.7482465825333 0.000211248493285506 GRK4 other 9.96955317144595e-13 1 0.0230292765085484 4.84633405739399 -3.7482465825333 0.00117180267393783 120.484347140985 97.6420075780612 1.23393967544821 0.218133700446815 -763.442665457539 229.957015804623 -3.31993639240031 0.00100468258619595 SOX9 other 1 1 1 1.23393967544821 -3.31993639240031 0.128959830950629 4113.56452924116 2203.65543417477 1.86670042214727 0.0628934635669616 3593.28723536604 4177.29039704036 0.860195699564463 0.390350242178608 MYH2 other 1 1 1 1.86670042214727 0.860195699564463 0.000659003019764589 55.3502843078991 14.3243075857878 3.86408096701415 0.000135086496086693 15.7407991755693 29.6802723861751 0.530345509325623 0.596241371594657 HS3ST3B1 other 1 1 1 3.86408096701415 0.530345509325623 8.9049712313527e-12 136.472164045559 19.6157916000881 6.95726009063772 1.97515437431906e-11 -87.3140255586527 37.2016925659411 -2.34704443632198 0.0195341485100433 SLC25A35 other 1.14687124488591e-07 1 2.71721987275073e-07 6.95726009063772 -2.34704443632198 1.47581885388612e-06 244.461263015865 47.4454605395176 5.15246896617754 4.50599116710039e-07 -39.9664027415221 117.671397059613 -0.33964415941518 0.734347327376406 MRPS7 essential 0.0150828686867162 1 0.005457656501592 5.15246896617754 -0.33964415941518 1.48321949626577e-07 102.363455145445 21.5027717319991 4.76047722690162 2.93027884542738e-06 -127.418345386332 53.3298899744226 -2.38924823297859 0.0174616799704479 GGA3 other 0.00162115890941849 1 0.0340205373954118 4.76047722690162 -2.38924823297859 6.44042933885451e-05 71.6020159899387 16.0532674025386 4.46027678942267 1.13464566633519e-05 28.5110242154747 39.8143548644638 0.716099113310566 0.474452390308643 ARMC7 essential 0.566693377525809 1 0.126773960299631 4.46027678942267 0.716099113310566 1.12058404999951e-06 156.81195490581 31.8012083469249 4.9310061804923 1.31649021325209e-06 -96.8027361710448 78.8714572861964 -1.22734813710595 0.220593909311464 NUP85 essential 0.0115621862278949 1 0.015604358497677 4.9310061804923 -1.22734813710595 0.0181804575436631 35.0445843928679 12.3017606084727 2.84874543638341 0.00467343001277601 13.6114518241289 30.5100918113381 0.446129494080076 0.655805427129053 SLC25A19 other 1 1 1 2.84874543638341 0.446129494080076 0.000175924958025381 77.9707125871162 18.7823237231088 4.15128147808383 4.24398473375013e-05 65.5820868372565 46.5827973296473 1.4078606394794 0.160143034688688 MIF4GD other 1 1 0.455676640862751 4.15128147808383 1.4078606394794 0.00329528567999003 106.202563640749 33.7976650946296 3.14230475221864 0.00183302145514968 -66.1363978769866 83.8229500528403 -0.789001077095182 0.430695543418793 NT5C other 1 1 1 3.14230475221864 -0.789001077095182 3.01852137586311e-08 126.381567279177 21.4277687974639 5.8980273902402 9.37729414683065e-09 89.1937311013546 74.1459406228242 1.20294827137034 0.229888387002733 MSTO1 essential 0.000342390879664153 1 0.00012124841331852 5.8980273902402 1.20294827137034 0.11745155951172 4.02721104763735 8.00153374301873 0.503304888409808 0.615096191221214 55.9843066867933 27.9386016637341 2.00383352612325 0.0459304938436059 C1orf61 other 1 1 1 0.503304888409808 2.00383352612325 1.23852316473646e-13 72.2847954802471 10.5226195021421 6.86946776565776 3.36803288740427e-11 -76.1851312898216 21.7666727924038 -3.50008161635107 0.000531097332731892 TTF1 other 1.66135497317748e-09 1 4.6162258754763e-07 6.86946776565776 -3.50008161635107 3.37721240369885e-10 254.424274587309 40.9251693230409 6.21681666309121 1.58705221639265e-09 -190.194558422053 85.6595088612034 -2.22035546258186 0.0270970152589186 GTF3C4 essential 4.15734846895328e-06 1 2.10030490317403e-05 6.21681666309121 -2.22035546258186 1.2905042136774e-21 114.732645807748 11.7237234392807 9.78636577380636 5.99021704163362e-20 -75.6307904917596 24.5386496487376 -3.08210890062773 0.00223463204820554 DDX31 other 1.89329873188612e-17 1 8.89307622000927e-16 9.78636577380636 -3.08210890062773 5.76189153632821e-05 135.340558192893 41.9975368535131 3.2225832354159 0.00140123141692549 -240.20249941373 109.601507952028 -2.19159849076953 0.0291288857151956 PPP1R12C other 0.510215495541863 1 1 3.2225832354159 -2.19159849076953 1.95890309230547e-08 329.282477071061 66.9893714201954 4.91544360083055 1.42152697781203e-06 -363.347446126315 165.257228209036 -2.19867808545544 0.0286207577317619 MBOAT7 other 0.00022450988340913 1 0.0168109780396051 4.91544360083055 -2.19867808545544 0.0286838413119401 4.6866418481594 1.99474441982744 2.34949490349487 0.0194063625331627 -6.4773934485223 9.12443159489711 -0.709895556907328 0.478285877010451 SRMS other 1 1 1 2.34949490349487 -0.709895556907328 0.182622112833964 4.95015592184811 2.78674491556535 1.77632186361911 0.0766419954072 11.3782046540909 12.7759171184433 0.890597876348565 0.37382249558956 OPRL1 other 1 1 1 1.77632186361911 0.890597876348565 1.13030828560978e-10 292.190837807289 48.2490157685586 6.05589219081427 3.93671930340986e-09 -447.176329497766 217.982277099872 -2.05143434341171 0.0410434925192143 SLC2A4RG other 1.40994655546964e-06 1 5.15355924009385e-05 6.05589219081427 -2.05143434341171 0.00379353077623143 5.21721600210848 1.56645332793061 3.33059141251324 0.000967931737298265 2.02532197324874 7.16532709415386 0.282655899254228 0.777623367946922 FNDC11 other 1 1 1 3.33059141251324 0.282655899254228 5.95325985585371e-10 901.514827748747 160.934860399426 5.60173740798772 4.57675083476951e-08 -1729.34437706222 736.154020712042 -2.34916108369485 0.0194234669452855 PPDPF other 7.26000039421359e-06 1 0.000577540187839565 5.60173740798772 -2.34916108369485 0.693865477056613 -7.12196503912386 110.261167792778 -0.064591779514876 0.94853936101428 299.906288680873 360.028388794547 0.83300733501884 0.405461880274698 IL1B other 1 1 1 -0.064591779514876 0.83300733501884 0.00622438487159642 63.2311474971713 21.6608781870074 2.91914053305089 0.00375883027389023 -61.986423525429 70.4704791763302 -0.879608372895088 0.379731563006191 CHCHD5 other 1 1 1 2.91914053305089 -0.879608372895088 0.586987731396236 2.87891998707588 27.5688153571289 0.104426684635596 0.916896167436818 -89.9848765099683 90.0186019492857 -0.999625350332186 0.31824713480847 PAX8 other 1 1 1 0.104426684635596 -0.999625350332186 0.000240026375989684 50.8452863318748 16.2729517140498 3.1245275734442 0.00194658762799043 -114.779814785031 51.7097831154486 -2.21969244250689 0.0271514462177971 INSIG2 other 1 1 1 3.1245275734442 -2.21969244250689 7.35167631512942e-06 161.496377143857 32.6966701137053 4.9392300984241 1.26594608606037e-06 40.9447791517165 106.37380398387 0.384914120002001 0.700556744724187 POLR1B essential 0.0710245448804654 1 0.0150217162571923 4.9392300984241 0.384914120002001 0.00108173492424124 90.183619901248 28.4565180925497 3.16917268683196 0.00167884083959673 -134.523719565911 90.424921344548 -1.48768412032488 0.137834547909856 CCDC93 other 1 1 1 3.16917268683196 -1.48768412032488 0.093884828880991 72.5228897119999 56.6277360371934 1.28069555287124 0.201228068936085 -286.749544869682 184.90274477112 -1.55081280823945 0.121934956954967 PSD4 other 1 1 1 1.28069555287124 -1.55081280823945 0.000208821611831526 202.973346412846 132.32324705706 1.53392053873437 0.126037259979469 -661.920204900452 237.947262361246 -2.781793740058 0.0057266147457393 SLC25A23 other 1 1 1 1.53392053873437 -2.781793740058 1.29233630025947e-06 13.3403262489364 5.49488905554446 2.42776989928045 0.0157431435536817 -31.2781952449583 9.95920594433717 -3.14063143384872 0.00184320684319007 PSPN other 0.0132710014673645 1 1 2.42776989928045 -3.14063143384872 6.08240013943002e-16 228.085395400878 64.5447522999825 3.53375584030152 0.000470051559429902 -662.821036576059 116.984069065624 -5.66590854524164 3.26201220189088e-08 GTF2F1 other 8.47339163423996e-12 0.000494455809562619 1 3.53375584030152 -5.66590854524164 2.00011727154706e-05 154.045076653911 59.7198480009813 2.57946196801069 0.0103413378896865 -258.392066083676 108.239176295317 -2.38723237673839 0.0175559973776777 ALKBH7 other 0.185650885144998 1 1 2.57946196801069 -2.38723237673839 8.96846134537544e-11 147.725559335492 48.9127896353127 3.02018266463463 0.00272964060955348 -387.971268429362 89.2353927542043 -4.34772859125543 1.85081332735928e-05 CLPP other 1.12338946812173e-06 0.2706074165932 1 3.02018266463463 -4.34772859125543 0.265221326606494 19.1622528647421 26.2893278911217 0.72889854560388 0.466596839587767 -46.7289503733525 47.3631859935293 -0.98660910141764 0.324579695176137 TNFSF9 other 1 1 1 0.72889854560388 -0.98660910141764 8.43335169304625e-06 152.338597324988 37.369532639277 4.07654542526641 5.78887849285139e-05 -237.340984915503 93.9452283472392 -2.52637615652225 0.0120126577725048 MED1 essential 0.0810529431218675 1 0.613621120242248 4.07654542526641 -2.52637615652225 0.0607893066836248 1037.57161873559 442.312776180159 2.34578713211977 0.0196009440342032 -221.715231394343 1084.23955517005 -0.204489155867007 0.838102080272107 RPL23 essential 1 1 1 2.34578713211977 -0.204489155867007 6.19022913883436e-05 3.71482789574174 6.44582216200689 0.576315604491504 0.564807003705624 -62.3624327393999 15.0849429479697 -4.134084759518 4.55704959007735e-05 ATG4C other 0.546102014627967 0.658220242790773 1 0.576315604491504 -4.134084759518 0.925532530571646 -6.50074577676829 29.2582111917878 -0.222185345992475 0.8243113359816 -20.5341858191012 52.7119637388143 -0.389554559584372 0.697125085662022 CD70 other 1 1 1 -0.222185345992475 -0.389554559584372 0.506762500796139 441.062397687783 716.198425986146 0.615838267279737 0.538439043813119 -794.751772380267 1290.31215247273 -0.61593760149993 0.538373561600921 C3 other 1 1 1 0.615838267279737 -0.61593760149993 0.000255341247535089 65.4997631428261 47.7504258287599 1.3717105555816 0.171114519512783 -245.474394503186 85.4436189409753 -2.87294004567808 0.00433844051337235 SH2D3A other 1 1 1 1.3717105555816 -2.87294004567808 0.00112712509265834 180.442732173996 90.7489218906085 1.98837328769048 0.0476220136590978 -314.821062352503 162.384233580077 -1.93874156013585 0.0534118325293712 TRIP10 other 1 1 1 1.98837328769048 -1.93874156013585 0.249140743154677 -3.97801969964691 6.94949247425441 -0.57241873624357 0.567440259794146 14.4422069422224 12.5202936332922 1.15350385264285 0.249564468257177 TNFSF14 other 1 1 1 -0.57241873624357 1.15350385264285 0.233525565634396 918.555970774003 589.286216164747 1.55876031981919 0.120041529015254 -436.390486233075 1413.68027545817 -0.308691076623843 0.757757399132426 FOSB other 1 1 1 1.55876031981919 -0.308691076623843 2.4578118402985e-07 102.955807437596 27.2602593919346 3.77677284567794 0.000189389015886029 -207.856087620988 65.3965593443941 -3.17839485295193 0.00162560227328286 OPA3 other 0.00265394522515432 1 1 3.77677284567794 -3.17839485295193 0.00022547862040105 671.158626905442 228.116779684796 2.94217123279063 0.00349713630763063 -1172.10690074062 547.24543540193 -2.14183038343619 0.032961780332075 SNRPD2 essential 1 1 1 2.94217123279063 -2.14183038343619 0.00227753772104447 84.4819813401066 24.8258714421163 3.40298150407666 0.000751252484410728 -4.0155249742616 59.5565343564193 -0.0674237515270863 0.946286468274801 RTN2 other 1 1 1 3.40298150407666 -0.0674237515270863 5.50837047888212e-06 395.721650356775 88.2828928043813 4.48242731730168 1.02926078166297e-05 -235.889985714743 211.788059510713 -1.1138021013069 0.266199988468287 VASP other 0.0537947460967628 1 0.115359548408786 4.48242731730168 -1.1138021013069 3.01316796457708e-09 434.597731992918 92.0757504023593 4.72000206453687 3.53149575128759e-06 -697.091060493249 220.887013171601 -3.15587163991257 0.00175233907003588 SYMPK essential 3.57753432434236e-05 1 0.040817027893382 4.72000206453687 -3.15587163991257 0.0208377646288948 62.0463490642381 42.0459562836359 1.47567934109246 0.141013262202412 -298.726652534948 159.02435362297 -1.87849625374486 0.0612222917518458 GPCPD1 other 1 1 1 1.47567934109246 -1.87849625374486 0.000344768929630284 -35.0745861824205 71.9167468061305 -0.487710967752377 0.626088550533083 -1069.43015296249 267.314377891787 -4.00064583654912 7.85245135932169e-05 SDCBP2 other 1 1 1 -0.487710967752377 -4.00064583654912 9.07316132559704e-12 123.29653029086 20.4880434034243 6.01797486773442 4.83147285476024e-09 -189.643014662487 75.7427402716773 -2.50377810443968 0.0127850461219866 PANK2 other 1.16816952067062e-07 1 6.30700466460402e-05 6.01797486773442 -2.50377810443968 0.519700080277005 474.617843334669 1195.53972966675 0.396990440014038 0.691639148772829 -4021.50845307113 4374.8073153077 -0.919242417603091 0.358661174076477 TGM3 other 1 1 1 0.396990440014038 -0.919242417603091 0.391790897874601 3.7103699421601 3.19964962108565 1.15961757740873 0.247079984545936 14.1149647489205 13.6718044128643 1.03241418050416 0.302667624615462 FOXA2 other 1 1 1 1.15961757740873 1.03241418050416 0.427020711827633 -1.51471740843476 3.63490494160099 -0.416714448595072 0.677195557373656 -20.8554387758767 15.9881532078902 -1.30443075599153 0.193121031380665 FAM182A other 1 1 1 -0.416714448595072 -1.30443075599153 0.124572725083628 -57.2860354109928 54.7961964506951 -1.04543817128873 0.296619537277401 325.420165499762 234.492895980841 1.38776129715397 0.166187494622915 CD93 other 1 1 1 -1.04543817128873 1.38776129715397 5.02528538495239e-17 73.7733491335224 8.71854522510102 8.46165813547955 9.96874744043116e-16 -43.3978823220375 37.8239761300519 -1.14736436414883 0.252098995624296 GZF1 other 7.08364227862888e-13 1 1.44417244169526e-11 8.46165813547955 -1.14736436414883 0.423085336088081 -42.3985149908695 90.935434828214 -0.466248553943405 0.64135883686741 -503.009875557601 383.75183443815 -1.31076865415916 0.190887731247082 PAX1 other 1 1 1 -0.466248553943405 -1.31076865415916 2.66014891390014e-08 36.4998360459777 7.27943118714339 5.01410551286508 8.89685926427262e-07 -60.3247142610484 31.5806163016923 -1.91018166601821 0.0570148554082072 NAPB other 0.000302645141934419 1 0.0106299674489529 5.01410551286508 -1.91018166601821 3.07015721233403e-18 580.739822196117 72.6418222559222 7.99456572207301 2.39093699960193e-14 -763.844611615411 268.551299294498 -2.84431545712898 0.00473725566501775 CENPB other 4.38664062498286e-14 1 3.42453906452984e-10 7.99456572207301 -2.84431545712898 3.22388135240041e-34 768.713745597269 62.3975352363961 12.3196171561098 8.30241522770304e-29 -775.626731476946 232.069676766618 -3.34221489978184 0.00092961095988524 PSMF1 other 4.89836532683719e-30 1 1.25897824512889e-24 12.3196171561098 -3.34221489978184 0.269840207292218 5.32761103379481 4.18874959479875 1.27188577718043 0.204348931655526 -10.3680428165521 17.6767213357773 -0.586536531272196 0.557933774359226 NKX2-2 other 1 1 1 1.27188577718043 -0.586536531272196 2.50249761892401e-16 284.836536422255 34.6427789183329 8.22210415318385 5.15103392441401e-15 -200.228552722239 147.748178608905 -1.35520149627192 0.176315198497172 DTD1 other 3.50274591720794e-12 1 7.42263988508059e-11 8.22210415318385 -1.35520149627192 2.76926945881835e-10 268.020906562712 61.6837092267717 4.34508413846142 1.87366278343884e-05 -921.284682435961 232.387356104898 -3.96443549200715 9.08510981475336e-05 RBCK1 other 3.42004778164067e-06 1 0.206402692223622 4.34508413846142 -3.96443549200715 0.0324188789232124 82.4820272922116 41.1372869173272 2.00504295429045 0.0458029837128788 -163.495145775841 153.813238321615 -1.0629458657777 0.288610494568895 TMX4 other 1 1 1 2.00504295429045 -1.0629458657777 8.87799714457172e-17 312.110123848628 41.2141306281774 7.57289111990254 3.94504336631689e-13 -413.959226142577 150.813792040567 -2.7448366660738 0.00639602543399566 STK35 other 1.24780249866956e-12 1 5.56448366818998e-09 7.57289111990254 -2.7448366660738 9.0365951169957e-13 1400.81165062262 199.846389767914 7.00944186306997 1.42372170863192e-11 -930.631780515829 731.292675767625 -1.27258457708326 0.204089352942925 SNRPB essential 1.19165579807822e-08 1 1.96430884139946e-07 7.00944186306997 -1.27258457708326 6.79252945378693e-05 124.135747897926 28.8591581627848 4.30143343744533 2.25880494733128e-05 6.57844191669999 108.72406262417 0.0605058508477546 0.951790644597107 NRSN2 other 0.596519936631568 1 0.247293965633828 4.30143343744533 0.0605058508477546 1.39043784430739e-19 92.3813311683635 10.0078599537532 9.23087768966211 3.78461539052173e-18 -40.6903359445401 36.9982980915472 -1.099789396903 0.272250569008119 AP5S1 other 2.01210260449723e-15 1 5.56565539330125e-14 9.23087768966211 -1.099789396903 1.67192118548817e-12 1493.2053030111 199.945998486118 7.46804294317883 8.00142982336313e-13 -1.71848264363577 797.608683302367 -0.00215454354950184 0.998282283788623 RRBP1 other 2.19222305841209e-08 1 1.12412087588429e-08 7.46804294317883 -0.00215454354950184 4.9945520909453e-05 194.132922844023 47.1139326447557 4.12049922276299 4.81980708614117e-05 -106.304295670804 176.440272428476 -0.602494511075393 0.547271715090974 BMP2 other 0.445863665158687 1 0.515140981366768 4.12049922276299 -0.602494511075393 2.8361177232122e-18 101.527269583058 11.4866455352609 8.83872225981004 6.81560892682577e-17 -70.9490821842437 46.7245028814709 -1.51845558130869 0.129896255604782 ZNF133 other 4.05479750887648e-14 1 9.94738122870221e-13 8.83872225981004 -1.51845558130869 0.00697702226450277 142.284079035389 54.9757398602264 2.58812486011357 0.0100986203539039 -253.779736518774 221.002751940821 -1.14831030061892 0.251714534541774 FLRT3 other 1 1 1 2.58812486011357 -1.14831030061892 7.1417083865236e-06 30.0812130667986 7.42733729517012 4.05006691783877 6.44341060081594e-05 -54.9074842943693 30.2123576273437 -1.81738495789138 0.0701021913913412 OVOL2 other 0.0690674618060698 1 0.681004066400237 4.05006691783877 -1.81738495789138 0.210976303537398 68.7944091979909 39.8117523449826 1.72799249331864 0.0849696062484919 14.4974178062912 161.249118847125 0.0899069583135875 0.928418290263221 PCSK2 other 1 1 1 1.72799249331864 0.0899069583135875 5.54447530757359e-13 195.351812366738 29.6954247064854 6.57851552209233 1.9625757902369e-10 -272.107809168444 115.534486408842 -2.35520854098521 0.0191213873563926 MKKS other 7.34310309735047e-09 1 2.65124363503103e-06 6.57851552209233 -2.35520854098521 0.0014886980585637 21.0947215312281 6.13745404668867 3.4370475722925 0.000666808663536201 -8.77065163893417 24.4830438121922 -0.358233710898582 0.720407608767711 BFSP1 other 1 1 1 3.4370475722925 -0.358233710898582 7.85249357642555e-20 1764.78578358731 186.248762405671 9.47542287418485 6.52594292941113e-19 -779.681041448531 742.968757933889 -1.04941295730487 0.294790013936088 DSTN other 1.13837599377441e-15 1 9.63685992386141e-15 9.47542287418485 -1.04941295730487 0.0142256672194154 41.1577508251182 15.6301392004167 2.633229960231 0.00887093663447587 -31.9404421577197 60.1535970308005 -0.530981416478971 0.595802303240998 LAMP5 other 1 1 1 2.633229960231 -0.530981416478971 4.46804892986314e-17 243.948980024749 27.4993582783453 8.87107901048187 5.53056347510576e-17 -11.8062814867575 110.930247518902 -0.106429776826612 0.915309115788931 SNRPB2 other 6.30352343025092e-13 1 8.07517573000192e-13 8.87107901048187 -0.106429776826612 8.77039908602518e-13 194.1266754844 26.8430803747271 7.2319075446785 3.59577480545976e-12 -118.995823581972 109.190240307002 -1.08980274470868 0.276627779513323 MGME1 other 1.15672793545586e-08 1 5.00819514904435e-08 7.2319075446785 -1.08980274470868 5.9828639964865e-23 192.129211283917 20.5759464277339 9.33756374020053 1.74302651860126e-18 -238.43325431017 77.5178705955933 -3.07584886527732 0.00228068303199739 TBC1D20 other 8.84566441880529e-19 1 2.56887248311454e-14 9.33756374020053 -3.07584886527732 1.01440388438512e-12 280.475699057943 41.8379667353504 6.70385587407044 9.18180630897071e-11 -286.815033628888 153.096579218183 -1.87342548797344 0.0619209762113335 ITPA other 1.3364771176774e-08 1 1.24845020383075e-06 6.70385587407044 -1.87342548797344 0.535081000590863 2.64053108459674 3.60129416729053 0.733217271885171 0.46396439049074 -8.39590248497356 13.5675244012306 -0.618823466734436 0.536474300744326 TCF15 other 1 1 1 0.733217271885171 -0.618823466734436 0.000484236002812959 85.7655354880853 24.7599055309904 3.46388783191187 0.000604941484976643 -77.5503423802769 92.7251076689217 -0.836346749331079 0.403583948461486 MCM8 other 1 1 1 3.46388783191187 -0.836346749331079 0.255218426219748 4.34637831093144 3.02640423045848 1.43615260221632 0.151935772521806 -4.72027861576607 11.2558396556336 -0.419362638433067 0.675232503903302 TMEM74B other 1 1 1 1.43615260221632 -0.419362638433067 1.31324774519523e-12 152.500701370936 29.6448445723724 5.14425707305138 4.69962413262043e-07 -466.549333748584 111.684059513793 -4.1774030759597 3.81031044178785e-05 FAM110A other 1.72600151151008e-08 0.551999673701805 0.00568748512529724 5.14425707305138 -4.1774030759597 5.17368750522621e-10 226.896153730992 38.3334034690661 5.91901926772795 8.33699922377528e-09 -207.16292700454 140.272422367642 -1.47686140659625 0.140696212305984 MRPS26 essential 6.32897192514322e-06 1 0.000107972476947114 5.91901926772795 -1.47686140659625 0.107040423432688 -10.6190461607563 13.5458041700305 -0.783936193633335 0.433661069371094 -49.8479287887139 23.6824285770452 -2.1048486909417 0.0360887724356326 S1PR4 other 1 1 1 -0.783936193633335 -2.1048486909417 1.09754712243974e-05 252.250145379306 149.552795517528 1.68669629013883 0.0926393890460707 -832.202582342161 261.746953186457 -3.17941650212577 0.00162052419622052 NCLN other 0.104321853987898 1 1 1.68669629013883 -3.17941650212577 0.0112413959787911 128.171036375491 113.400755820761 1.13024851949025 0.259217960175254 -513.917244507659 219.081320410414 -2.34578303410312 0.0195972988902575 HNRNPR other 1 1 1 1.13024851949025 -2.34578303410312 0.0209175741256443 66.4638706912669 36.252163846779 1.83337664952025 0.0676753197667399 -104.105290151401 70.0363226488564 -1.48644712077985 0.138145466680014 ZNF436 other 1 1 1 1.83337664952025 -1.48644712077985 1.16539692581376e-10 215.333720159625 35.0860548856843 6.13730215212898 2.50386915498865e-09 -214.958867344054 117.348085380525 -1.83180549258223 0.0679185896083204 MAX other 1.4530168871046e-06 1 3.29759567712005e-05 6.13730215212898 -1.83180549258223 4.46295506329295e-28 211.027937189885 18.0415688294659 11.6967620268826 1.62574604072533e-26 -78.6730286141957 60.3414537854642 -1.30379736779142 0.193248680290022 CHURC1-FNTB other 6.71630107474955e-24 1 2.45650226753597e-22 11.6967620268826 -1.30379736779142 0.0384170274653356 16.1955019538388 7.62696409535892 2.12345328381628 0.0345001084295822 -77.810353774638 66.0634005345803 -1.17781332999819 0.239765778919117 MMP24 other 1 1 1 2.12345328381628 -1.17781332999819 4.10237028405655e-09 74.7399844329469 11.7385051077528 6.36707858001309 6.9090942538005e-10 0.275797811455424 73.7230901206242 0.00374099635547247 0.997017522200525 NECAB3 other 4.84859143872644e-05 1 9.23469537962975e-06 6.36707858001309 0.00374099635547247 0.00913091114206542 385.344073204249 135.477757744155 2.84433459499646 0.00474930481418744 -703.710854915846 837.767356140689 -0.839983618074598 0.401571243179115 ID1 other 1 1 1 2.84433459499646 -0.839983618074598 3.1236625149168e-16 1062.80962575057 123.847767357837 8.58158082640084 4.53056034824666e-16 -1193.06164699731 778.455596243184 -1.53260077100738 0.126390837192094 RALY other 4.3662554633507e-12 1 6.5774675135845e-12 8.58158082640084 -1.53260077100738 5.51440741156331e-16 528.946213533533 62.7213820457736 8.43326783117617 1.26531588623471e-15 -621.394463478947 385.27019843326 -1.61287965175067 0.107781635699507 DYNLRB1 essential 7.68763537246042e-12 1 1.8324304664451e-11 8.43326783117617 -1.61287965175067 8.28279019450343e-08 263.646194754493 46.1079954506661 5.71801467787914 2.52869841786784e-08 -176.444064595801 289.815697576683 -0.608814726293822 0.543091683451532 EIF2S2 essential 0.000918147293060705 1 0.000322383761293971 5.71801467787914 -0.608814726293822 1.60868697368567e-06 373.015410714435 79.2027289105921 4.70962826464619 3.73096336675275e-06 -1237.69687206217 686.249215145336 -1.80356763220494 0.0722575112970382 ERGIC3 other 0.0163844768269885 1 0.0430553172523267 4.70962826464619 -1.80356763220494 0.00775578828179586 204.75890719342 78.8479594021786 2.59688276964797 0.00985154001626208 -595.113869548444 451.888634974495 -1.31694807855045 0.188819386870153 ROMO1 essential 1 1 1 2.59688276964797 -1.31694807855045 8.28096798334708e-05 211.686687998118 50.2261307533537 4.21467241897752 3.27383060935844e-05 -329.984083910956 435.182515594692 -0.758265950689725 0.44886052392452 FAM83C other 0.719284879033527 1 0.354621331605706 4.21467241897752 -0.758265950689725 2.81098997587377e-11 -1304.23229777059 1719.60410403522 -0.758449165543444 0.448752846612406 80332.0958604852 11369.0687341236 7.06584661761898 1.04096598921805e-11 BPIFB1 other 3.57754694229455e-07 1.5940312192896e-07 1 -0.758449165543444 7.06584661761898 0.00281503371409674 72.7432583373224 22.6565182602363 3.21069890359066 0.00146121565187784 -176.160326265499 196.306593066566 -0.897373458087396 0.370207188919599 CEP250 other 1 1 1 3.21069890359066 -0.897373458087396 1.87847751209261e-05 186.98066810732 39.6979470091598 4.71008407724905 3.74673828390993e-06 -4.10444536558444 245.662822894248 -0.016707637391887 0.986680636786926 PLAGL2 other 0.174905041150943 1 0.0432298663197527 4.71008407724905 -0.016707637391887 1.24115562031938e-11 177.238008265915 43.1685937168219 4.1057165176277 5.13333711991284e-05 -184.254707169038 61.4317014163408 -2.99934240662308 0.0029199530460671 TMEM115 other 1.59227854530773e-07 1 0.54711107024031 4.1057165176277 -2.99934240662308 1.69008497958055e-05 398.821790377831 145.221088636245 2.7463076755802 0.00637025621177202 -1150.91896865167 346.636410588927 -3.32024834522227 0.00100393695105928 PSMB2 essential 0.158107449839761 1 1 2.7463076755802 -3.32024834522227 1.35682305200956e-05 90.0630626640048 19.9255867141783 4.51997042576012 8.73551607047237e-06 -37.734101004445 47.5702322468732 -0.793229278524812 0.428235693703345 AGO3 other 0.128043391418142 1 0.0985191502427874 4.51997042576012 -0.793229278524812 9.12501235509476e-06 161.031908434204 48.8211716973027 3.29840318935034 0.00108185803122941 -368.070268934369 123.908154125189 -2.97050885418319 0.00319803364565329 UROD essential 0.0874315036232917 1 1 3.29840318935034 -2.97050885418319 0.0172442479426273 40.9139391276118 14.4877078173256 2.82404502102696 0.00503953670681274 44.4325323552222 45.6933894429175 0.972406137888492 0.331582991955336 ST3GAL3 other 1 1 1 2.82404502102696 0.972406137888492 4.57619887960276e-08 44.0859428377216 11.1790541134182 3.94362013015083 9.86473428528154e-05 -104.684625110913 28.3724440012935 -3.6896583567542 0.000263822888956571 TMEM53 other 0.000513724086224206 1 1 3.94362013015083 -3.6896583567542 4.17265092622251e-14 249.259676450036 38.0044990528714 6.55868864639604 2.17999592317977e-10 -358.320362339956 96.4554344432899 -3.71487997963066 0.000239835100760036 HECTD3 other 5.64142405225283e-10 1 2.94277649670037e-06 6.55868864639604 -3.71487997963066 1.91323687118776e-27 500.152794152326 47.0294616381917 10.6348824062694 8.59814804263049e-23 -364.203307193222 138.502908653713 -2.62957154281726 0.00896618253992793 KLC1 other 2.87502104633385e-23 1 1.28912033603159e-18 10.6348824062694 -2.62957154281726 0.0108300283691206 48.8357109172367 21.8747556083989 2.2325145840023 0.0262790899728065 -82.7417098320796 64.4216874341591 -1.28437663041106 0.199948034003034 XRCC3 essential 1 1 1 2.2325145840023 -1.28437663041106 1.21095587864383e-12 135.716161680369 20.5979120009562 6.58883102685693 1.86175345687136e-10 -122.882753571663 50.4788042618156 -2.4343435897236 0.0154740313329489 TUBGCP3 essential 1.59228588482877e-08 1 2.51634597230734e-06 6.58883102685693 -2.4343435897236 0.319221981074321 -49.9754932957166 33.0319386541194 -1.51294460246535 0.131296361442048 -32.6338791750712 80.9505723508376 -0.403133396434022 0.687123576263518 MCF2L other 1 1 1 -1.51294460246535 -0.403133396434022 0.198208528730041 0.210661048748256 1.59699497557092 0.13191090264573 0.895138979750468 6.95867732284184 3.90827788795408 1.78049706861673 0.0759583787054705 F10 other 1 1 1 0.13191090264573 1.78049706861673 3.74846676279609e-19 165.738036493948 17.2915592517452 9.58490984421897 2.92121486452661e-19 -2.61684253121636 42.3171141460128 -0.0618388702544102 0.950730366659056 PCID2 essential 5.40191545186545e-15 1 4.32106102760777e-15 9.58490984421897 -0.0618388702544102 0.203630365662824 137.001981730748 112.400532173294 1.21887307009833 0.223790128645955 -658.37412676803 554.864942615942 -1.18654843044163 0.236285958913865 SLURP1 other 1 1 1 1.21887307009833 -1.18654843044163 2.66843005808266e-29 117.303690195934 9.44532887114319 12.4192277258141 3.71471138990882e-29 -21.9568631988712 43.7117967401564 -0.502309784459174 0.615796183698841 LRFN3 other 4.02692780065255e-25 1 5.63521717849168e-25 12.4192277258141 -0.502309784459174 0.00434266714441921 12.9409937304371 9.3997783231053 1.37673392771691 0.169563009181856 -120.710660137047 44.3756645583579 -2.72019949083357 0.00688304142526872 IGFLR1 other 1 1 1 1.37673392771691 -2.72019949083357 1.38694428046217e-07 977.026149610684 275.346095908649 3.5483566468828 0.00044625671566568 -2573.13348254925 776.249891738203 -3.31482620472566 0.00102328767982741 CAPNS1 other 0.00151856529267803 1 1 3.5483566468828 -3.31482620472566 1.26711642214775e-10 48.0984020300014 7.74313992731538 6.21174387670888 1.62806511016484e-09 -39.1757520904313 24.3527207214941 -1.60868071122148 0.108672267296613 PDCD2L other 1.57844692706945e-06 1 2.1540929472591e-05 6.21174387670888 -1.60868071122148 1.92605604649562e-44 842.814448690256 51.6900822632429 16.3051481403733 6.75122925960476e-44 -197.806657390485 253.751792819777 -0.779528117584471 0.436246621272803 RBM42 essential 2.9476361735569e-40 1 1.0333431504751e-39 16.3051481403733 -0.779528117584471 1.31282080059583e-09 416.176024160954 74.0703563938883 5.61865831923139 4.18698349070582e-08 -464.635433015965 232.956490510859 -1.99451593727674 0.0469437432972046 UBA2 essential 1.57945470519684e-05 1 0.000528983494215773 5.61865831923139 -1.99451593727674 0.788983032212743 0.0896914061372416 4.36383184587542 0.0205533598234349 0.983614755626594 -14.5253338020061 21.589140961154 -0.672807400171315 0.501555387490852 FFAR2 other 1 1 1 0.0205533598234349 -0.672807400171315 0.0480774874740461 7.008632943774 7.58536340924452 0.923967984873654 0.356199174037967 -73.4937227280557 35.4106157197731 -2.0754714718789 0.0387413391049408 HCST other 1 1 1 0.923967984873654 -2.0754714718789 6.6945485887601e-19 1169.40557678462 127.098651989804 9.20077088526819 4.78665865967589e-18 -983.79370361909 623.940017025739 -1.57674404073125 0.115845566410218 COX6B1 other 9.6274303254959e-15 1 7.03590956385759e-14 9.20077088526819 -1.57674404073125 0.865689658605718 77.6557901319122 329.28140317651 0.235834120550941 0.813712728265038 -445.05596283834 960.550104099265 -0.463334459013652 0.643440603745018 KRT36 other 1 1 1 0.235834120550941 -0.463334459013652 2.14762022888427e-06 170.9355108841 32.8315910971143 5.20643396107368 3.47489506562436e-07 68.3419536576276 94.9441239567265 0.719812357095174 0.472172575490737 THRA other 0.0216415690464667 1 0.00422859980535828 5.20643396107368 0.719812357095174 8.46767113395008e-06 88.0438595868483 18.0713929809235 4.8720018251935 1.74795706649234e-06 -17.7325489661893 51.8319803933742 -0.342115983831019 0.732490313538598 CCR7 other 0.0813743195972603 1 0.020552479187817 4.8720018251935 -0.342115983831019 0.111678147355021 15.5632702720477 54.7305638139948 0.284361592271194 0.77631953754181 -325.080470000219 158.27272639961 -2.05392601362947 0.0408052915196367 NR1D1 other 1 1 1 0.284361592271194 -2.05392601362947 4.07285742591544e-05 251.434300295461 77.1987342998923 3.25697438663592 0.00124882383260984 -867.539573820395 344.474341638181 -2.51844468210528 0.0122826119067486 FRMD8 other 0.367168096946277 1 1 3.25697438663592 -2.51844468210528 6.09570195277551e-05 785.442433522428 249.088482745 3.15326676234368 0.00176905683481155 -2158.59468179461 968.453797060823 -2.22890827455658 0.0265207093635667 PRDX5 other 0.53847061744606 1 1 3.15326676234368 -2.22890827455658 5.78472397048383e-05 91.32360027472 28.163244293971 3.24265199426154 0.00130911801110861 -154.680953471112 65.9181832421884 -2.34655971786726 0.0195572109034356 BCL2L12 other 0.512121613106933 1 1 3.24265199426154 -2.34655971786726 0.000123217407742269 191.751754849143 71.7928555518034 2.67090302196967 0.00795145866967977 -459.657757337873 168.03655709356 -2.73546283789868 0.00657669820526109 IRF3 other 1 1 1 2.67090302196967 -2.73546283789868 1.28699546122689e-07 672.172832793614 144.197954037985 4.6614588762927 4.61544153329826e-06 -793.471558704827 337.50611464388 -2.35098424673597 0.0193302118715478 PRMT1 essential 0.00141106182368916 1 0.0529437298284644 4.6614588762927 -2.35098424673597 0.0135801457700111 128.47221319617 66.3021103925056 1.93767909400802 0.0535419646392345 -274.477036492739 155.185056685128 -1.76870790497345 0.0778952397247225 RRAS other 1 1 1 1.93767909400802 -1.76870790497345 0.004901222799869 22.7468719065807 12.0331604957768 1.89034891660957 0.0596175428526812 -62.7925610427011 28.1559467912918 -2.23017046836166 0.026431521877538 PRRG2 other 1 1 1 1.89034891660957 -2.23017046836166 3.16919549765696e-10 337.554596947799 66.4396608875506 5.08061890200058 6.40644167339936e-07 -531.129352967459 155.507003923975 -3.41546901146085 0.000718799891412481 SCAF1 other 3.90571653131244e-06 1 0.00770438675643007 5.08061890200058 -3.41546901146085 4.16135794599207e-05 219.966199799052 61.1455163625976 3.59742157535535 0.000372361128800029 -283.709906270846 143.07213020516 -1.9829851269008 0.0482264531121897 PRR12 other 0.374647055877666 1 1 3.59742157535535 -1.9829851269008 0.392022831990712 9.52987182455722 12.6723186392665 0.752022743101479 0.452591887400642 37.6839223391622 29.4855554033943 1.27804688850542 0.20216208073523 TSKS other 1 1 1 0.752022743101479 1.27804688850542 0.0385769805928041 41.4592215139414 26.4572824892288 1.56702494032863 0.118152586663214 -160.639992887097 99.1439263750596 -1.62027063845947 0.106214376556517 ASL other 1 1 1 1.56702494032863 -1.62027063845947 8.17630049078192e-10 400.898857864807 61.3435817806442 6.53530241025643 2.67393357761155e-10 13.9031935140156 232.113805837725 0.059898175654987 0.952276089415991 SBDS other 9.92357590566202e-06 1 3.60259070911604e-06 6.53530241025643 0.059898175654987 0.274328428529455 4108.89414476907 2762.81891272713 1.48721080699178 0.137946885467573 -359.594284859361 5940.23318208633 -0.0605353820021361 0.951767143816606 STATH other 1 1 1 1.48721080699178 -0.0605353820021361 0.406360821227127 522.39750285621 453.760909729363 1.1512615821574 0.250486800023393 -240.037701974867 975.61429027841 -0.24603750105625 0.805811434055001 HTN1 other 1 1 1 1.1512615821574 -0.24603750105625 0.558616958418804 -32.8471312315103 45.9005876019265 -0.715614612962638 0.4747511755016 -102.715707428611 118.427517274389 -0.867329737147367 0.386411282644972 STAT5A other 1 1 1 -0.715614612962638 -0.867329737147367 0.607749268226424 -2.50373800037308 6.37415205218523 -0.392795462027727 0.694732082430405 -14.778292728013 15.616983857884 -0.946296215869647 0.344711523786802 WNK4 other 1 1 1 -0.392795462027727 -0.946296215869647 4.76914488790189e-05 162.525792920041 38.9679656794776 4.17075385091594 3.91425130316759e-05 -137.33878739161 95.4734192106928 -1.43850286841124 0.151268726872318 BECN1 other 0.426552318773945 1 0.421486580325086 4.17075385091594 -1.43850286841124 1.76403700533106e-06 463.299363174856 101.677980891489 4.5565358311874 7.40742849585211e-06 -378.520309604495 292.205787124737 -1.29538950384618 0.196119599218609 TRAP1 other 0.017892627345073 1 0.083896535144021 4.5565358311874 -1.29538950384618 0.00029133656069172 199.268368106062 49.6870308552282 4.01047043214687 7.55281712220526e-05 45.2962944163241 146.243850881807 0.309731275149013 0.756967546197807 GLIS2 other 1 1 0.792894741489108 4.01047043214687 0.309731275149013 4.0859822481375e-08 97.1668385628595 53.7443228452669 1.80794609400157 0.0715536686341623 -551.452515063094 107.775575144501 -5.1166742958572 5.3720084161483e-07 DNAJC8 essential 0.000459918161850357 0.00807520305115412 1 1.80794609400157 -5.1166742958572 0.318739832927927 28.0268552048342 89.9896364687054 0.311445365318047 0.75566487259859 -246.462171908762 180.337365985916 -1.36667279441139 0.172687325871041 AHDC1 other 1 1 1 0.311445365318047 -1.36667279441139 0.278881396985381 1120.50559285791 1195.29905615269 0.937426987070904 0.349245923686912 -2489.71359399633 2395.35452981844 -1.03939252540836 0.2994069181495 IFI6 other 1 1 1 0.937426987070904 -1.03939252540836 6.0538417410301e-44 419.938455821504 25.5995975972589 16.4041037842903 2.79042565608515e-44 -40.7973458432173 141.47593882068 -0.288369500731342 0.773251191205097 ZNF384 other 9.26237786377605e-40 1 4.27186263690075e-40 16.4041037842903 -0.288369500731342 1.17114857352529e-36 439.218714467542 30.1864789146963 14.5501804204699 3.86741862794265e-37 -52.8104180455377 169.518773533812 -0.311531383484227 0.755600186240337 EMG1 other 1.78412773690843e-32 1 5.90554824486843e-33 14.5501804204699 -0.311531383484227 3.61829741641425e-19 186.465124237959 19.6284640175704 9.4997308027284 5.20727325408053e-19 -21.5229812793098 63.7533609567967 -0.337597594170684 0.735888493513737 PCNX4 other 5.21505206627786e-15 1 7.6947876875548e-15 9.4997308027284 -0.337597594170684 2.7922064264835e-14 138.841149075483 17.2033606808394 8.07058293151526 1.45164283498161e-14 -5.12823926776438 53.2659843790589 -0.0962760629986688 0.923361966439797 ATG14 other 3.7901410033087e-10 1 2.08310746819862e-10 8.07058293151526 -0.0962760629986688 4.16990492119704e-24 2427.80527147273 224.304141716594 10.8237202081638 1.83554788148751e-23 -526.588763343675 689.853019456831 -0.763334722747601 0.445827948155646 KTN1 other 6.19147482699336e-20 1 2.75607514405349e-19 10.8237202081638 -0.763334722747601 0.5523180578239 10.0198220392186 20.0834385280118 0.498909687464289 0.618186868941464 69.1605280720404 65.2311207124427 1.06023823163977 0.289838315631698 SIX1 other 1 1 1 0.498909687464289 1.06023823163977 0.342684278177286 8.0087651718616 7.27746887821811 1.10048772531784 0.271957276292062 28.9424090461091 24.209511647119 1.19549743373503 0.232789108634234 RHOJ other 1 1 1 1.10048772531784 1.19549743373503 0.000423809970344128 99.6982008699091 29.9041689339368 3.333923142628 0.000957783190132595 -124.115608936339 89.6477557960438 -1.38448093690949 0.167184998818215 DLGAP5 other 1 1 1 3.333923142628 -1.38448093690949 1.58210697602439e-08 44.1832141021343 7.18573107171445 6.14874306610984 2.33274285366879e-09 23.2796937658573 22.7240505169418 1.02445176965705 0.306398163846677 L3HYPDH other 0.000181894839033524 1 3.07478835542083e-05 6.14874306610984 1.02445176965705 1.02162334374086e-11 931.827151124184 154.715786565348 6.0228317472348 4.75927904648026e-09 -1424.71931160576 516.834763627423 -2.75662438340315 0.00617949756796496 HSPA2 other 1.31339897071324e-07 1 6.21466657889392e-05 6.0228317472348 -2.75662438340315 3.39128819325483e-08 97.1387913860163 16.9921072607088 5.71670069495337 2.51446559307235e-08 -28.2062644277899 56.7628678015406 -0.496914012984811 0.619595216884028 ZBTB1 other 0.000383520781775189 1 0.000320619507772656 5.71670069495337 -0.496914012984811 5.35753652687477e-30 154.722404325141 12.6522767142895 12.2288191934972 1.83984206005677e-28 -53.9280364880102 41.7516450427647 -1.29163860328794 0.197417383873169 TRMT5 essential 8.09738070671852e-26 1 2.78828064201603e-24 12.2288191934972 -1.29163860328794 1.64047087168135e-12 110.502446561937 15.3666813980107 7.19104168947251 4.67984641878561e-12 -48.2647390724129 50.8754526968631 -0.948684218300604 0.34350618686944 SGPP1 other 2.15114945403576e-08 1 6.50685846067951e-08 7.19104168947251 -0.948684218300604 2.32073059320104e-15 538.954985295514 68.7374832643748 7.84077274436439 6.93125671525715e-14 -394.995655636142 229.620530030927 -1.72021053859139 0.0863731852385235 PLEKHG3 other 3.20933833733772e-11 1 9.88189269894211e-10 7.84077274436439 -1.72021053859139 0.303677790763069 7.63081586561677 5.43477564722734 1.40407191776348 0.161273301708308 -11.6659078206449 28.4047763868887 -0.41070232913468 0.681567417483569 PZP other 1 1 1 1.40407191776348 -0.41070232913468 2.09329952760357e-05 94.9745139534137 22.2949158330738 4.25991803084191 2.70596020318202e-05 -80.4666707710368 54.8574194767065 -1.46683295602711 0.143422307952701 RHOT1 other 0.194090732199403 1 0.294679066126522 4.25991803084191 -1.46683295602711 0.952947854504085 -1.53396388878316 11.2404676651616 -0.13646797753242 0.891538790969192 -8.21255612418425 27.8580474634959 -0.29480013396293 0.768341375061496 EVI2A other 1 1 1 -0.13646797753242 -0.29480013396293 4.27310516260152e-06 25.2476111135855 12.1686369653135 2.0748101192889 0.0388288645250185 -84.2654336233742 27.6509512026094 -3.04746961527392 0.00250633212351593 WDR60 other 0.042111451377438 1 1 2.0748101192889 -3.04746961527392 0.00646843662189533 77.9297368366024 46.6813166358652 1.66939886131509 0.0960224435851338 -243.593673128762 95.849360873338 -2.54142198663863 0.0115148442474454 AIF1L other 1 1 1 1.66939886131509 -2.54142198663863 0.0119340028059361 -17.0945162905433 10.0961102881815 -1.69317844225157 0.0914008170894125 -54.825208493026 20.8438974021591 -2.63027625953229 0.00894669718053381 FAM78A other 1 1 1 -1.69317844225157 -2.63027625953229 2.56346650193338e-11 317.827621263189 51.6134358665028 6.15784661352995 2.22316263313613e-09 -341.884058103751 106.558380511518 -3.20842017739558 0.00147068729937007 NUP214 essential 3.26585632346313e-07 1 2.93123993178999e-05 6.15784661352995 -3.20842017739558 1.33647403823516e-08 345.889550681027 130.512252839235 2.65024580571062 0.00844305723831515 -900.54422179765 241.684059331164 -3.72612171563906 0.000229819425168444 MAP2K2 other 0.000154162280310426 1 1 2.65024580571062 -3.72612171563906 5.66069925162788e-09 2208.1417223975 515.559732123749 4.28299881626031 2.44324963977973e-05 -2499.42426568172 821.364653771251 -3.04301415236918 0.002536855552049 CANX other 6.64962341088727e-05 1 0.266851725656742 4.28299881626031 -3.04301415236918 2.29635429964705e-13 462.604596935374 59.7616617294093 7.7408255317593 1.31667009566197e-13 -105.420556585466 114.211568921529 -0.923028705243478 0.356689858810885 IPPK other 3.06609226088874e-09 1 1.86993486985913e-09 7.7408255317593 -0.923028705243478 8.59016712510589e-07 27.2371344038753 5.05584917632742 5.38725216159641 1.38917686242296e-07 3.18054965343432 9.64881301029738 0.329631183653366 0.741894320167653 ZNF484 other 0.00893635086024766 1 0.00171966203799338 5.38725216159641 0.329631183653366 0.669698338433843 -0.25512112258255 12.6537675635732 -0.0201616729010398 0.983926967607754 21.363479926371 24.1490267685107 0.884651796992002 0.377008673672044 OMD other 1 1 1 -0.0201616729010398 0.884651796992002 3.93466069468314e-05 -2.6615022106937 14.8944822584775 -0.17869048178421 0.858293820281574 -129.460884177998 28.42530882253 -4.55442313701046 7.47766526263657e-06 FGD3 other 0.355339207336834 0.110392772272304 1 -0.17869048178421 -4.55442313701046 4.30344129965743e-15 249.792059210244 31.7221007691335 7.8743857800647 5.36928977491164e-14 -199.170437278141 100.043444598498 -1.99083946057103 0.0473487112127891 HIVEP3 other 5.92368694897845e-11 1 7.66680886959633e-10 7.8743857800647 -1.99083946057103 1.84773737145595e-08 110.413457357872 21.3053733183732 5.18242303046878 3.89333591009252e-07 -155.76592967284 66.294111456964 -2.34961938925689 0.0194019011894316 PPCS other 0.000212009386000856 1 0.00472962446358039 5.18242303046878 -2.34961938925689 0.0221635033747054 142.339672506481 57.361854568619 2.48143428375747 0.0135986337125472 -142.752438227583 178.507941006852 -0.79969797098328 0.424479030172631 EDN2 other 1 1 1 2.48143428375747 -0.79969797098328 6.93611886264308e-05 106.409665933937 30.7467069756559 3.46084756387694 0.000613016339103876 -164.814128546025 93.1032969711784 -1.7702287019658 0.0776593555138877 BCL11B og 0.608783152574183 1 1 3.46084756387694 -1.7702287019658 0.00144127737037977 64.5014734337124 92.1603797404597 0.699882895614799 0.484510508198412 -667.718663123013 192.350717519254 -3.47136039695913 0.000589182959269672 TRAF2 other 1 1 1 0.699882895614799 -3.47136039695913 0.00445273004689579 44.7039671654206 19.5161415740659 2.29061502734872 0.0226397571881742 -73.9405090028188 45.5289556218414 -1.62403261820808 0.105359613209455 ABHD8 other 1 1 1 2.29061502734872 -1.62403261820808 0.479339649139928 -3.89532758530659 19.721143818434 -0.197520368046071 0.843546142443705 147.480460748584 122.257108032923 1.206313997783 0.228590319184176 MASP1 other 1 1 1 -0.197520368046071 1.206313997783 0.0557722401019364 59.601285006385 24.7482521828345 2.40830279916594 0.0165937624554569 -24.193407595994 149.234259404497 -0.162116980997093 0.871316371074644 ATP13A4 other 1 1 1 2.40830279916594 -0.162116980997093 0.000614540946683073 12.2764123423978 3.2043600268859 3.83115887084898 0.000153586125017784 12.9350886461608 19.236982170209 0.672407373033413 0.50181113092359 HRASLS other 1 1 1 3.83115887084898 0.672407373033413 1.93386031906939e-12 35.6335345359765 4.67485465761253 7.62238339922523 2.95412102683267e-13 -4.03680103040136 29.9039252805769 -0.134992346072485 0.892704142160563 HELB other 2.53006945543849e-08 1 4.17476383511993e-09 7.62238339922523 -0.134992346072485 7.75435661710021e-35 404.25252039076 28.5588890341948 14.155050636134 1.51778304462717e-35 -80.8911608001234 178.895662590373 -0.452169491584289 0.651458099096533 RAP1B other 1.17920501076243e-30 1 2.31552981288321e-31 14.155050636134 -0.452169491584289 0.70331333801752 -4.85077710092207 6.99729493209969 -0.693236050215549 0.488672245320395 15.3170516770395 38.0092746722628 0.4029819513556 0.687234870050302 TSPAN8 other 1 1 1 -0.693236050215549 0.4029819513556 0.394341121820718 6.34936018452869 5.18939793083478 1.22352540104923 0.222048676383623 21.650578718101 29.9677037820775 0.722463718793475 0.470547146248648 BEST3 other 1 1 1 1.22352540104923 0.722463718793475 0.00394234651203776 42.8990349106269 13.1116201580257 3.27183325886452 0.00118745704146902 -32.8749906778893 75.7169047808254 -0.434182971069026 0.664453765500695 RAB3IP other 1 1 1 3.27183325886452 -0.434182971069026 0.0894640948757282 20.6698998258608 9.38398000760116 2.20267943975988 0.0283413170033647 17.3946415346107 53.1752719837164 0.327118995083605 0.743795156215116 PTPRB other 1 1 1 2.20267943975988 0.327118995083605 1.03990041467927e-18 170.238920880982 17.7328063247145 9.60022445199307 2.68658728451853e-19 -80.7983746414932 112.908455908289 -0.715609597098047 0.474765932221442 DYRK2 other 1.49225709506476e-14 1 3.97453722871671e-15 9.60022445199307 -0.715609597098047 1.38129182016006e-31 137.267063706911 10.2669552165738 13.3697927780305 1.46451792981483e-32 12.2619202310051 58.6220329463756 0.209169140248372 0.834452268278047 YEATS4 essential 2.09210459081442e-27 1 2.22928919276414e-28 13.3697927780305 0.209169140248372 2.72496157328881e-06 20.9549250423725 23.6360623717217 0.88656582102453 0.375980573089371 -207.264418195226 52.6035506641816 -3.94012220806902 0.000100091427370057 LRRC61 other 0.0272659655023278 1 1 0.88656582102453 -3.94012220806902 0.223757784552056 14.2722667112463 16.7722769792912 0.850943895624208 0.395442829290934 -24.9073297479349 30.9403727879072 -0.805010654482796 0.421416896432541 IDUA other 1 1 1 0.850943895624208 -0.805010654482796 0.000101685584195155 107.180281463299 26.2318054474952 4.08589037753533 5.56792774719701e-05 46.8775152494963 48.3906770945572 0.968730302283141 0.333418287279206 FGFRL1 other 0.875207823167697 1 0.591035530364962 4.08589037753533 0.968730302283141 2.66027168421156e-09 26.7044757679793 15.0798555238851 1.77087079685094 0.0775430983714869 -118.792467197273 27.8183070833417 -4.27029821913242 2.5829767851031e-05 TMEM175 other 3.16652138571702e-05 0.376029760375309 1 1.77087079685094 -4.27029821913242 0.00532380988979334 6.22189499050854 10.2240547118185 0.608554547670441 0.543252815406299 -58.6438518080451 20.0546180021187 -2.92420687354152 0.00370056003526754 AUNIP other 1 1 1 0.608554547670441 -2.92420687354152 2.16175984355174e-06 104.858363530021 46.3681191857074 2.26143232400814 0.0244034219995387 -362.215711913517 99.5357066160596 -3.63905300145902 0.000318926042354714 PIN1 other 0.0217818921836274 1 1 2.26143232400814 -3.63905300145902 1.60723676842905e-19 113.525161241225 12.9121468441137 8.79212129569124 9.20149813381333e-17 -39.560750299485 28.1980704381708 -1.40295948214715 0.161598418601684 FBXL12 other 2.32358219611787e-15 1 1.34203850281667e-12 8.79212129569124 -1.40295948214715 3.93203392617007e-06 346.149434005499 97.1650208699478 3.56249019355236 0.000423225938447055 -442.863695593868 188.415734747358 -2.3504602531614 0.0193569738873005 EMC1 essential 0.038864223326265 1 1 3.56249019355236 -2.3504602531614 0.0301991977687307 278.01642278679 179.185043287781 1.55156042985284 0.121755848857659 -546.943020752696 347.463328721896 -1.57410286364481 0.116451796342092 UBR4 other 1 1 1 1.55156042985284 -1.57410286364481 0.00043615566529228 309.287201969267 155.692231640445 1.98652944151725 0.0478298955114886 -834.889671647469 303.321068687867 -2.75249482424386 0.00625283580911305 HP1BP3 other 1 1 1 1.98652944151725 -2.75249482424386 0.326962824159281 13.5195558459195 24.2260984122442 0.558057497161266 0.577196561463152 88.5464139470759 59.5487033657521 1.48695788392264 0.138013649275939 ADGRE2 other 1 1 1 0.558057497161266 1.48695788392264 1.82579443262846e-09 231.072992983895 42.610294757638 5.4229381490602 1.16222590707068e-07 -199.027417859111 99.9385265728275 -1.99149842092254 0.0472812617192579 SIN3B other 2.18401530031017e-05 1 0.00144290346362825 5.4229381490602 -1.99149842092254 1.32425384374486e-06 239.375027895559 61.7322781892175 3.87763152303958 0.000128178538309645 -370.923752138658 152.714922184286 -2.42886383880059 0.0157000869256469 SLC35E1 other 0.0135908171983535 1 1 3.87763152303958 -2.42886383880059 1.99613713729384e-15 211.749302108587 31.4647745824577 6.72972569861161 7.96438413336925e-11 -275.010360660085 78.2876441736555 -3.5128194693158 0.000507811371026733 EPS15L1 other 2.76305302544213e-11 1 1.08387303671022e-06 6.72972569861161 -3.5128194693158 0.0320175317060346 51.4052026124388 24.1312620800735 2.13023266010139 0.033919695668688 -56.8549255355998 59.4546462508714 -0.956273884730522 0.3396602836746 KLF2 other 1 1 1 2.13023266010139 -0.956273884730522 0.48718690729744 7.1461328293856 6.93865362214342 1.02990194042545 0.303838725331187 14.3679446396442 16.2739737741881 0.88287868955725 0.377968738352648 F2RL3 other 1 1 1 1.02990194042545 0.88287868955725 6.8932160204804e-06 169.130837994927 105.893194130464 1.5971832692718 0.111218046826366 -571.971446680294 174.833039668365 -3.27152949903089 0.00118714769654981 UQCR11 other 0.0667745835903936 1 1 1.5971832692718 -3.27152949903089 0.124658274916055 29.7480101917461 18.9979656470707 1.56585240464065 0.118374597199834 -44.5616797783108 53.9706598516203 -0.825664905725124 0.409611253501722 GFER other 1 1 1 1.56585240464065 -0.825664905725124 0.27837453967145 -27.8988264613438 19.9495327229157 -1.39847017215079 0.162943323172477 -64.832105860254 56.67393366159 -1.14394928446961 0.25350234230037 SYNGR3 other 1 1 1 -1.39847017215079 -1.14394928446961 0.00796791087036299 1.56078380832012 104.616807102904 0.0149190541323334 0.988106084887007 -903.190128984776 300.607610466114 -3.00454844634277 0.00287046173459694 PKMYT1 essential 1 1 1 0.0149190541323334 -3.00454844634277 0.683595470627691 -0.235176659120405 3.44409673163971 -0.068283987775349 0.945602485136193 -7.90094596924402 9.29741619414096 -0.849800181498064 0.396075520213707 WFIKKN1 other 1 1 1 -0.068283987775349 -0.849800181498064 2.42216571140431e-08 59.0960432935668 15.550306608429 3.8003137032381 0.000173166941468982 -141.93365426195 41.9784006520145 -3.38111152538963 0.000811986372684733 WDR24 essential 0.000276175334414319 1 1 3.8003137032381 -3.38111152538963 0.00104523042529487 61.744734566174 18.8617520669617 3.27354183996121 0.00117900301926726 -37.7409981713716 50.9177217661222 -0.741215373789216 0.459109865848818 FBXL16 other 1 1 1 3.27354183996121 -0.741215373789216 0.0299968088052327 80.3374201917936 40.2761137359286 1.99466663339289 0.0469325472310462 -117.00868669397 108.726270271511 -1.07617677311818 0.282663983951816 CHTF18 other 1 1 1 1.99466663339289 -1.07617677311818 9.14306812330099e-12 791.993425273547 167.079261336324 4.74022580025233 3.23360275477623e-06 -1441.26837509564 359.896404055255 -4.00467567571018 7.74680743618003e-05 SMARCA4 other 1.17690343285966e-07 1 0.0374677551195921 4.74022580025233 -4.00467567571018 8.22089181067318e-10 146.024968952565 43.5663911133094 3.35178024208563 0.000899139904506924 -294.963076769881 80.947643997266 -3.64387475909544 0.000313242406239412 KDM4B other 9.97523012307084e-06 1 1 3.35178024208563 -3.64387475909544 8.85848957286461e-10 176.784317528528 52.5167396901298 3.36624700184413 0.000854817592205332 -365.99812817067 99.6678396031302 -3.67217880540049 0.000281754140209408 TICAM1 other 1.07373752112692e-05 1 1 3.36624700184413 -3.67217880540049 0.296426825528804 -2.58909414957903 3.94492574737636 -0.656309982843391 0.512097823545391 -14.0624383518778 9.28827650162744 -1.51399867880913 0.131016312318902 METTL25 other 1 1 1 -0.656309982843391 -1.51399867880913 2.58382293811964e-09 107.697984998755 16.8994815230498 6.37285734783415 6.46369449983118e-10 -29.760039822422 32.0277357833336 -0.929195870221595 0.35348797164546 EMC6 other 3.07810826618192e-05 1 8.64389865462423e-06 6.37285734783415 -0.929195870221595 2.86508771364912e-17 232.608097483134 25.8113731216961 9.01184514231102 1.92894524049603e-17 -84.9254655945136 49.1450365917986 -1.72805783623501 0.0849486287749535 METTL16 other 4.05094751832849e-13 1 2.82378293756214e-13 9.01184514231102 -1.72805783623501 4.47439683141665e-06 2158.04495626451 747.743376940546 2.88607699220865 0.00416585596210501 -3083.76492102302 1312.48097383486 -2.34956923757359 0.0194025555699799 TUBA4A other 0.0440146416306456 1 1 2.88607699220865 -2.34956923757359 0.00836852725311115 6.63113245213107 23.6883258848352 0.279932507023478 0.779710150469383 -109.34131198436 41.561271452025 -2.63084617395729 0.00892941590646076 VIL1 other 1 1 1 0.279932507023478 -2.63084617395729 6.68401776101808e-17 414.767570460224 82.2102504913777 5.04520504415353 7.60891043761865e-07 -646.761327149481 144.238244332769 -4.48397947535572 1.02223933813065e-05 AAMP essential 9.40708659685685e-13 0.150453185786068 0.00911547470426715 5.04520504415353 -4.48397947535572 0.000909369541802919 -5.12609698296798 58.3205092318706 -0.0878952713287815 0.930014893009409 -348.202503587177 102.323588724259 -3.402954371797 0.000751324461113933 PNKD other 1 1 1 -0.0878952713287815 -3.402954371797 0.847204374135059 3.42922451421986 61.5933330302361 0.0556752548613737 0.955635366578628 -48.4276636159955 99.8226906040316 -0.485136829341681 0.627912278227153 TNFRSF19 other 1 1 1 0.0556752548613737 -0.485136829341681 1.45235730492154e-11 142.307060333255 35.8569708173027 3.96874183985965 8.93012595663581e-05 -275.261137773908 67.1182699721978 -4.10113576955915 5.22314768926253e-05 RNF6 other 1.85974352895203e-07 0.753125665314764 0.930697727200584 3.96874183985965 -4.10113576955915 2.81704885118204e-05 230.139298818974 116.351139062439 1.97797203081503 0.0488170891498954 -696.152301196438 235.123100015929 -2.9607992628086 0.00330531495644839 ECHS1 other 0.258182527210834 1 1 1.97797203081503 -2.9607992628086 2.06949697041844e-08 273.56201604653 48.5694491001644 5.63238869525501 3.95931280987317e-08 -233.357356349667 214.788475641624 -1.08645194139292 0.278115076441204 AKAP9 other 0.000236750453415869 1 0.000500655104808462 5.63238869525501 -1.08645194139292 0.793049523391258 11.0368035192114 16.4208206619345 0.67212252946627 0.502006310047769 18.3751080768803 70.9513323712481 0.258981860703247 0.795821118854576 GNG11 other 1 1 1 0.67212252946627 0.258981860703247 0.00277382213232496 357.676362552602 107.044459125613 3.34138137998232 0.000934594741269604 -87.5088034806351 457.445312169156 -0.191298940338196 0.848415422811254 SEM1 other 1 1 1 3.34138137998232 -0.191298940338196 0.000187288244705826 9.59914749853107 2.34223793321291 4.0982802653886 5.32022307205794e-05 0.147537973581718 10.1257967593838 0.0145705051254352 0.988384202922354 GNGT1 other 1 1 0.566124937097685 4.0982802653886 0.0145705051254352 8.88526504105299e-05 203.673833013928 50.0955898511657 4.06570385974184 6.03772053277726e-05 -83.4864203289901 173.546425030944 -0.48106102049699 0.630802919418811 HIP1 og 0.769375099904779 1 0.639273850010457 4.06570385974184 -0.48106102049699 5.74147634675427e-07 496.744099278123 101.343979781664 4.90156495085661 1.51602305860085e-06 -395.234930585099 355.440065397785 -1.11195942455946 0.266992903997699 PTPN12 other 0.00604520044549757 1 0.017904232322076 4.90156495085661 -1.11195942455946 0.0582045622283739 -81.2070429940757 39.4829069387797 -2.05676454167854 0.0405217826289195 -237.626280721075 136.780849759676 -1.73727741228823 0.083303399647241 FGL2 other 1 1 1 -2.05676454167854 -1.73727741228823 0.000432551472136568 91.7094186850818 33.1983920194142 2.76246568302015 0.0060694027930866 -232.28499876166 115.009370462799 -2.01970498427165 0.0442497706321727 STYXL1 other 1 1 1 2.76246568302015 -2.01970498427165 0.323217165641096 -157.010695187165 112.302472191664 -1.39810542121637 0.163068172757015 -388.319911921988 433.966250585618 -0.894815924966439 0.371570884322704 STEAP4 other 1 1 1 -1.39810542121637 -0.894815924966439 5.984802483665e-08 267.360700567898 52.1466115129591 5.12709633110975 5.12128522936467e-07 -294.509503786251 189.737062619907 -1.55219807727408 0.121609463830311 GNAI1 other 0.000667963805201851 1 0.00618702468559546 5.12709633110975 -1.55219807727408 0.000431836638313311 7.21458445044509 1.92910477716349 3.73986137811199 0.000218226327720118 -2.10928899992546 6.68300819655982 -0.315619693689923 0.752497573049389 PMS2P3 other 1 1 1 3.73986137811199 -0.315619693689923 1.36295808947698e-05 82.019143580945 17.2403522038123 4.75739373600547 3.01069369907023e-06 22.2472401382895 74.4369384992773 0.298873658519762 0.765236699256925 PEX1 other 0.128595095742153 1 0.034936089684011 4.75739373600547 0.298873658519762 4.7053337492207e-05 33.0787090955015 7.41682237149874 4.45995703262571 1.14191182695586e-05 6.05958185497768 32.9951522904795 0.183650670911621 0.854405668545546 MTERF1 other 0.42126853056773 1 0.127551551070969 4.45995703262571 0.183650670911621 0.099811228163019 35.3164149191103 16.5059926660013 2.13961169338541 0.0331667689956748 52.3511732828595 71.7383263444186 0.729751807025988 0.466092957592417 SGCE other 1 1 1 2.13961169338541 0.729751807025988 8.05236868125734e-10 38.0797256041865 5.93400201455288 6.41720806814652 5.17078660339514e-10 -11.1417894390698 25.6656847326844 -0.434112300338558 0.664507901012157 RBM48 essential 9.77718605278266e-06 1 6.92781989122881e-06 6.41720806814652 -0.434112300338558 3.52431073139967e-06 41.607511464421 8.82704202325709 4.71364148429286 3.68149298127223e-06 -33.7833617675172 38.3849481743477 -0.880120030749302 0.379476062357653 CASD1 other 0.0349505895232905 1 0.0425101994547505 4.71364148429286 -0.880120030749302 4.48507300421398e-05 27.3438549463333 7.87078864285278 3.47409340881786 0.000583201925033379 -46.6458219012708 24.2126422218312 -1.92650688321875 0.0549265257363145 ZNF780B other 0.402355899208036 1 1 3.47409340881786 -1.92650688321875 2.43873292690916e-08 43.5181030329661 7.24269391702977 6.00855200171331 5.10548326320427e-09 13.7916576226501 22.7144372383312 0.607175844945712 0.544166149031574 LRFN1 other 0.000277918004350567 1 6.66010291684998e-05 6.00855200171331 0.607175844945712 0.000602287777420896 1366.58611050818 433.847447102656 3.14992313458242 0.00178779797225804 -1907.66143966627 1360.62640795193 -1.40204646074579 0.161873678931248 ZFP36 other 1 1 1 3.14992313458242 -1.40204646074579 0.024519407594074 25.4923076418951 41.764217739679 0.610386331208009 0.542050267153545 -199.735549999508 88.9110535366361 -2.24646477636446 0.0253734187748019 SRD5A3 other 1 1 1 0.610386331208009 -2.24646477636446 0.138701984693352 26.8182409266335 17.1184732040925 1.56662575025804 0.118249382098559 63.7078471620561 36.6151870713242 1.73992958271542 0.0828901013158681 RASL11B other 1 1 1 1.56662575025804 1.73992958271542 2.76728593297795e-08 743.265530348108 136.198647526016 5.45721667468197 9.80813266465327e-08 -117.561767607178 290.282316373549 -0.404991144744394 0.685758911301863 PAICS essential 0.000314419027704955 1 0.00122179908603586 5.45721667468197 -0.404991144744394 0.321272135247549 -29.1378274809123 31.1355583689836 -0.935837640539592 0.350082887084035 49.024787250989 66.6923588641684 0.735088518173982 0.46283953369382 KDR og 1 1 1 -0.935837640539592 0.735088518173982 5.27759705239959e-07 121.784135796185 24.0647616289549 5.06068323775348 7.11470826072092e-07 -5.15774377488489 51.2896043794852 -0.10056119241481 0.919962777869538 PPAT essential 0.00557103144851301 1 0.0085326696170826 5.06068323775348 -0.10056119241481 2.03774186811513e-05 113.336642854895 27.6860790467753 4.09363285654911 5.38638166804385e-05 -92.8873211571817 78.8392252978475 -1.17818662989472 0.23960035789448 TUBGCP6 essential 0.189041313105041 1 0.572733962763103 4.09363285654911 -1.17818662989472 0.797537625029054 8.6900235663786 21.0802540200434 0.412235239580889 0.680443895224446 -24.4738505614343 59.8495912772732 -0.408922601460234 0.682870856667412 ADM2 other 1 1 1 0.412235239580889 -0.408922601460234 0.000153198125033702 171.711427800755 41.1113309041186 4.17674212983342 3.8515109046305e-05 6.62546304621483 166.768967017604 0.0397283929060701 0.968335321229036 DGCR6L other 1 1 0.415000299973937 4.17674212983342 0.0397283929060701 0.0125557780646316 22.1138488507985 9.88532762659591 2.23703752532212 0.0259743880642805 -41.2308188175933 28.6979270105194 -1.43671766962401 0.151778252016257 ASPHD2 other 1 1 1 2.23703752532212 -1.43671766962401 0.22416304323872 -3.27123548526282 2.39205492394316 -1.36754196256932 0.172421227125284 -9.58019610544166 7.25594267781527 -1.32032411649732 0.187676341616356 VPREB3 other 1 1 1 -1.36754196256932 -1.32032411649732 2.36941445182208e-05 147.520526942997 32.2654861282425 4.57208443587868 6.93978449598002e-06 -20.2722719225822 105.971846139206 -0.191298657720393 0.848414466998528 SDF2L1 other 0.218483706602514 1 0.0787873733828612 4.57208443587868 -0.191298657720393 0.000243457632540497 297.82681601371 85.8553087884222 3.46893884858838 0.000594088985688208 -341.736849116415 243.677631335226 -1.40241370225029 0.161761105178676 YWHAH other 1 1 1 3.46893884858838 -1.40241370225029 0.0184502127792507 1.58037586966627 0.878846287088789 1.798239228957 0.0730844498032664 -4.76194696189745 2.63171424411936 -1.80944681685641 0.0713227659801842 POM121L9P other 1 1 1 1.798239228957 -1.80944681685641 0.929388194635696 0.781342617458719 7.56087385650103 0.103340253029999 0.917757864665648 8.56817390181119 22.4365441852114 0.381884742636021 0.702801121331031 GNAZ other 1 1 1 0.103340253029999 0.381884742636021 0.011109866754202 -196.937194178584 78.0259206722135 -2.52399705741271 0.0120879629037315 -481.914259116553 220.779140983827 -2.18278890373912 0.0297801556701822 MGAT3 other 1 1 1 -2.52399705741271 -2.18278890373912 0.0114611406903675 -19.8770430780045 7.88604696967065 -2.52053318404654 0.0122051872033861 -49.7519382753574 23.6148487451934 -2.10680740800781 0.0359148084027609 ADORA2A other 1 1 1 -2.52053318404654 -2.10680740800781 0.0345755668127159 476.448611119282 225.83376757824 2.10973149068248 0.0356600834994731 -653.346627508193 639.010533698464 -1.02243483174957 0.307349874918815 ATF4 essential 1 1 1 2.10973149068248 -1.02243483174957 0.222107821033816 -8.0104462827541 130.117469281512 -0.0615631884556819 0.950949245746055 -572.087436774386 335.430664214557 -1.70553112105592 0.0890688455409174 A4GALT other 1 1 1 -0.0615631884556819 -1.70553112105592 0.000383140699343992 451.957253029123 140.102881632477 3.22589548311156 0.00138562605906831 -568.685732140336 362.125580112955 -1.57041027580253 0.117307922377493 CDC42EP1 other 1 1 1 3.22589548311156 -1.57041027580253 0.0265497375555232 -153.903124517706 71.4958030289609 -2.15261760827226 0.0320960496484086 -385.939559013736 186.904485755888 -2.0649026022725 0.039737435326007 APOL3 other 1 1 1 -2.15261760827226 -2.0649026022725 1.12613845048371e-09 205.764900662251 33.0446841958174 6.22686842588422 1.49891156437758e-09 -84.5418243456325 95.9314623610296 -0.881273174252956 0.378833486766361 TPST2 other 1.35744728821307e-05 1 1.9848586935488e-05 6.22686842588422 -0.881273174252956 0.817537619313845 15.208278155744 24.4733040539921 0.62142316877983 0.534766438959902 17.3612821616372 64.1977450006186 0.270434454691047 0.787001467556304 BAIAP2L2 other 1 1 1 0.62142316877983 0.270434454691047 0.0263961366318177 134.175747279411 76.5547862870377 1.75267613936413 0.0806152699466828 -316.838364875253 197.872064240186 -1.60122838002367 0.110313037467987 MPST other 1 1 1 1.75267613936413 -1.60122838002367 0.132061306455542 22.7829719391089 65.0185835282226 0.350407079065626 0.726263756129971 -311.020261260178 168.054304122337 -1.85071285668332 0.0651323115440249 TST other 1 1 1 0.350407079065626 -1.85071285668332 0.048844597299163 -11.1805720047279 5.06917545456121 -2.20559972819006 0.0281270886200413 -22.8805435993384 14.9147464742293 -1.53408867115998 0.126002113920358 IGLL1 other 1 1 1 -2.20559972819006 -1.53408867115998 0.0208180487291318 -154.099174106808 111.4583353087 -1.38257200486629 0.167760240331573 -778.738295521438 291.374625663571 -2.67263593646137 0.00791141350009607 APOL2 other 1 1 1 -1.38257200486629 -2.67263593646137 0.0290971100321282 -136.94764337672 97.4959203220411 -1.4046499886802 0.161095298446982 -640.454577543966 251.998861792728 -2.54149789799745 0.0115094047626993 RAC2 other 1 1 1 -1.4046499886802 -2.54149789799745 0.116510347926852 64.6957277983463 34.846830681498 1.85657422879196 0.0642993403312574 130.913717329432 96.9047178638759 1.35095297953738 0.177673953984973 LIF other 1 1 1 1.85657422879196 1.35095297953738 0.0755161881477103 38.8080306581294 17.0071611858412 2.28186410618827 0.0231598613681705 21.5906483734596 45.2229725760958 0.477426563172719 0.633387405127599 C22orf23 other 1 1 1 2.28186410618827 0.477426563172719 0.0257711185663451 -4.27658192899944 12.9958502215837 -0.32907288527355 0.742315864220501 -98.5382860204546 36.4254443503429 -2.70520477588977 0.00719179348530274 APOBEC3F other 1 1 1 -0.32907288527355 -2.70520477588977 0.00671109843684114 -38.9165926375316 13.1251720832974 -2.96503484987106 0.0032546457235758 -60.7448683528895 32.7720313597025 -1.85355822732378 0.0647254791185411 RIBC2 other 1 1 1 -2.96503484987106 -1.85355822732378 0.563520630606708 9295.4831900595 17575.3274739143 0.528893882851177 0.597245721017116 -40537.4710479587 45537.0392381492 -0.890208755908705 0.374022578351175 KRT17 other 1 1 1 0.528893882851177 -0.890208755908705 2.32485650438305e-09 193.16735435972 48.8188922318293 3.956815600043 9.37762500695559e-05 -331.20657241362 101.920649699978 -3.24965130607573 0.00127953290478283 EMC4 other 2.77378629537942e-05 1 0.974804119473034 3.956815600043 -3.24965130607573 1.049414236763e-05 195.537755132834 42.1310857601203 4.64117531283571 5.06083636020265e-06 -90.0539645764853 77.6054667350136 -1.16040748629188 0.246747921656009 SPECC1 other 0.0999567060516761 1 0.0579516371606805 4.64117531283571 -1.16040748629188 0.0160316587181031 79.8779718505249 93.1512038675695 0.857508744214248 0.39180554504172 -449.377435103031 215.651811997372 -2.083810151841 0.0379705502220462 CPA4 other 1 1 1 0.857508744214248 -2.083810151841 0.0789188478384379 30.2500273280045 19.3402550723553 1.56409660652529 0.118802113262588 -58.2951390312221 54.4457420293758 -1.07070152519493 0.285125959076356 DOCK4 other 1 1 1 1.56409660652529 -1.07070152519493 8.96507820675582e-09 77.3112237998647 18.5987040837082 4.1568070254737 4.15734885799031e-05 -103.93738114858 44.1142894158813 -2.35609328688773 0.0190767083941414 POT1 other 0.000104326615092017 1 0.446665561302479 4.1568070254737 -2.35609328688773 6.9124067375219e-11 190.392553686292 70.1072184309204 2.71573395646689 0.00697324192695955 -742.179017720733 161.284150296053 -4.60168600794556 6.05611340550764e-06 ATP6V1F essential 8.6964989164763e-07 0.0896668150819461 1 2.71573395646689 -4.60168600794556 1.06359486591108e-05 42.1619320022585 20.6911469729477 2.03767978920562 0.0424146184395487 -167.625144000613 52.9146811811211 -3.16783811711631 0.00168583534708993 LSM8 other 0.101232959337416 1 1 2.03767978920562 -3.16783811711631 0.616836583013722 -11.8280960191549 19.173544471839 -0.616896684727614 0.53774707945491 -62.4194482020279 69.0626852640641 -0.903808590172311 0.366785388462244 CDHR3 other 1 1 1 -0.616896684727614 -0.903808590172311 7.1114040104804e-09 91.2243091703115 16.3633738052689 5.57490834444777 5.29181396019263e-08 -93.9035680910809 64.7894027256638 -1.44936616391873 0.148220786635762 PRKRIP1 essential 8.31109786704844e-05 1 0.000666133541309048 5.57490834444777 -1.44936616391873 0.700818977642804 6.15435229777912 9.90758787361726 0.621175646008393 0.534926281329159 -16.7128060485619 41.2198701490792 -0.405455087270218 0.685413970042275 VGF other 1 1 1 0.621175646008393 -0.405455087270218 0.663363441650795 -77.9492198783063 158.77070766645 -0.490954666789446 0.623795027921597 -327.895087245781 363.08153382799 -0.903089407463838 0.367157742699794 PODXL other 1 1 1 -0.490954666789446 -0.903089407463838 0.00764960014169408 40.1762294736663 24.4641084242614 1.64225193810141 0.10154527621342 -122.679808454989 65.5002572136131 -1.87296681988437 0.0620078881895453 FOXP2 other 1 1 1 1.64225193810141 -1.87296681988437 0.0204402646624192 35.3405769775441 18.2109023261806 1.9406274518719 0.0531814998986063 -39.5927121181467 42.1595633947063 -0.939115800310163 0.348379596343996 STRIP2 other 1 1 1 1.9406274518719 -0.939115800310163 0.000179722364188915 53.6879250140669 14.1553456727575 3.79276679321166 0.000178086062295435 -50.9220023921214 58.8923881361815 -0.864661868939165 0.387872107103489 IFT22 other 1 1 1 3.79276679321166 -0.864661868939165 1.91674000979565e-17 188.643671549712 32.6871120254585 5.77119420653577 1.85960752211661e-08 -282.118131528739 74.0873853374127 -3.80791048629806 0.000167973859598549 MKLN1 other 2.71717063788631e-13 1 0.000238438876485791 5.77119420653577 -3.80791048629806 1.10357884555138e-13 136.50524578479 17.1892944085475 7.94129430448944 3.62378155749331e-14 7.70789272185711 73.4044318911382 0.105005822172811 0.916438446496676 DNAJB9 other 1.48221674746006e-09 1 5.18273238352693e-10 7.94129430448944 0.105005822172811 0.0741417679492051 908.861318795239 517.066527791132 1.75772607574856 0.0797532306857542 2507.59597391497 1189.52994353207 2.10805620114881 0.0358058325000533 FLNC other 1 1 1 1.75772607574856 2.10805620114881 0.0690112942087717 171.579738809083 99.5155882774963 1.72414936975138 0.085652700305993 -137.787776736242 230.148999026723 -0.598689446049877 0.54980620914595 LRRC4 other 1 1 1 1.72414936975138 -0.598689446049877 2.31371302138668e-07 1153.30512393682 234.584398227386 4.91637607893645 1.41325242238537e-06 -141.540216611419 539.669754236433 -0.262271908885613 0.79328110147684 CALU other 0.00250228063262969 1 0.0167173629043966 4.91637607893645 -0.262271908885613 0.0631094213396838 15.0917146445991 7.07898060073502 2.13190507161895 0.0337783968168333 1.11132677274992 16.2854467300936 0.0682404843519781 0.945636953211938 CCDC136 other 1 1 1 2.13190507161895 0.0682404843519781 2.97159481521739e-07 256.452693274761 54.3465054862026 4.71884421970552 3.55033325553571e-06 -75.0346845466891 125.816112913437 -0.596383744571047 0.551340541674555 SMO og 0.00319238430998804 1 0.0410276511009707 4.71884421970552 -0.596383744571047 0.00377297552478209 51.0300202153227 32.8511589949608 1.55337046778625 0.121323073009951 -148.493367327282 75.2119365945093 -1.97433245374143 0.0492035351709106 IRF5 other 1 1 1 1.55337046778625 -1.97433245374143 0.467702137206212 17.3749694439285 14.0877841312138 1.23333586617297 0.218361346851554 14.1196869102678 55.5557294030242 0.254153569073638 0.799541177699376 LRRC17 other 1 1 1 1.23333586617297 0.254153569073638 2.79402505047196e-15 159.013478916795 28.077197607837 5.6634383935956 3.30499288897375e-08 -213.083699083841 65.000754564014 -3.27817269988754 0.00115971176665101 KLHDC10 other 3.85715158217654e-11 1 0.000419172248108541 5.6634383935956 -3.27817269988754 6.8952543964518e-05 61.6952447617093 32.9274917515107 1.87366973552969 0.0618900291005136 -227.131102406803 80.8059334518808 -2.81082208575757 0.00524702452364618 NDUFA5 other 0.605265430920539 1 1 1.87366973552969 -2.81082208575757 0.96544698169407 -1.63644677224922 7.40078347555944 -0.221118044819643 0.825141985834674 0.710560025303927 18.8856372485605 0.0376243605631093 0.970010718678398 FEZF1 other 1 1 1 -0.221118044819643 0.0376243605631093 0.00020036093125084 5.8624823044106 1.59461864221608 3.67641651063565 0.000277439081066647 -0.368970203721672 3.66847692024014 -0.100578581177913 0.919948182807125 OPN1SW other 1 1 1 3.67641651063565 -0.100578581177913 2.89076839782683e-05 187.284146450772 52.7732791041469 3.54884421870339 0.000444889530641045 -328.002211841127 165.540963281432 -1.98139605653677 0.0484024604747639 MRPS12 essential 0.264678754505025 1 1 3.54884421870339 -1.98139605653677 0.0118181828956217 599.604271465723 301.728723287054 1.98722967085663 0.047765508845811 -1425.73472929925 796.075009775623 -1.79095526400345 0.0742635542814812 MYO1B other 1 1 1 1.98722967085663 -1.79095526400345 0.888581945339987 -0.380560249503553 2.39878690063711 -0.158646960012362 0.87405032877102 3.78963844315558 8.72527047354047 0.43432905084693 0.664351658789726 HOXD3 other 1 1 1 -0.158646960012362 0.43432905084693 2.48366683490532e-10 141.929132965756 20.9737174063821 6.7669993933726 6.66777956901904e-11 -31.2893258281642 77.9270084563077 -0.401520941814514 0.688315975972217 MTX2 other 3.07204750809438e-06 1 9.08751677461605e-07 6.7669993933726 -0.401520941814514 0.00789643333724478 13.8854619208054 4.42841388938221 3.13553842699706 0.00187871487370005 5.06544371769308 16.6434286139616 0.304350974500762 0.761063408803605 PDE11A other 1 1 1 3.13553842699706 0.304350974500762 0.90744327790578 4.65411142262815 18.1490159658127 0.256438775049573 0.797782147700338 26.4535859636429 68.2451046559521 0.387626132262597 0.698558738216101 CHN1 other 1 1 1 0.256438775049573 0.387626132262597 0.451711144803396 -7.20063544888554 7.84322804220206 -0.918070392718544 0.359277799315196 -23.8502950403954 24.2607851400262 -0.983080098304255 0.326315370059456 GAD1 other 1 1 1 -0.918070392718544 -0.983080098304255 0.0393860484455049 6.87787794111089 6.21255517376214 1.10709325691925 0.269106419421034 -32.1063209421465 15.7848794524004 -2.03399215299449 0.0427980525628622 OSGEPL1 other 1 1 1 1.10709325691925 -2.03399215299449 0.00118305363159426 58.2630763755574 21.8221561454217 2.66990465961729 0.00798594627538878 -109.973478203116 55.2283960197474 -1.99124881634793 0.0473281059374015 ORMDL1 other 1 1 1 2.66990465961729 -1.99124881634793 1.02641962100945e-10 236.990456438757 35.9179636653296 6.59810390831025 1.75491856743763e-10 -212.50988781817 132.212037633099 -1.60734144653231 0.108978171721367 HAT1 other 1.28261395841341e-06 1 2.37300088688916e-06 6.59810390831025 -1.60734144653231 0.0382355308134118 12.7898544845174 8.24602981163045 1.5510318027808 0.121914337537401 67.0537712901862 29.9938441469079 2.2355844406526 0.0260906941243661 HOXD9 other 1 1 1 1.5510318027808 2.2355844406526 0.0159851078062958 56.4349895939276 21.3355984427065 2.6451092874416 0.00858259839909099 -63.2524503861739 77.6054209225588 -0.815051959440983 0.415668296069546 HOXD10 other 1 1 1 2.6451092874416 -0.815051959440983 0.0364941793134181 34.0415182088721 13.7463842321171 2.47639798466693 0.0138050317294157 -20.5950169042677 50.0006567597054 -0.411894927765525 0.680701095018464 HOXD11 other 1 1 1 2.47639798466693 -0.411894927765525 0.388047915014178 11.0229127364863 12.5175605461098 0.880595919299309 0.379218746095763 53.1710434821995 45.530972928324 1.16779941350919 0.243785066212066 HOXD13 other 1 1 1 0.880595919299309 1.16779941350919 1.61568422304385e-05 235.805305787168 101.664084381655 2.3194553634294 0.021003495518151 -642.20133859172 220.519371227351 -2.91222188335384 0.00384248247438366 HERC2 other 0.15145423906813 1 1 2.3194553634294 -2.91222188335384 0.674398652830554 64.0255743114609 74.0860182832673 0.864205902747529 0.38812823674568 86.6007869018904 165.935070748475 0.521895621650471 0.602107473140837 SNRPN other 1 1 1 0.864205902747529 0.521895621650471 9.06558662397361e-46 386.533534161236 22.886991037066 16.8887877631112 1.031569561197e-45 0.280611358093001 96.837107665476 0.00289776682573352 0.997689801866963 PSMG2 essential 1.3875786886654e-41 1 1.57974562601708e-41 16.8887877631112 0.00289776682573352 1.17516033975369e-35 564.766314852554 39.0914468888993 14.4473116192824 1.06485649318524e-36 328.27497935886 164.959680338245 1.99003161673047 0.0474461519229203 TWSG1 other 1.78859403710512e-31 1 1.62592937944454e-32 14.4473116192824 1.99003161673047 0.0193348354010176 -4.77554101493254 15.8720077466714 -0.300878193304438 0.76370277613974 -89.5288746589787 33.1785025167388 -2.69840010451981 0.00733707381761679 ARHGAP22 other 1 1 1 -0.300878193304438 -2.69840010451981 8.47736165367325e-06 199.859343665918 56.5469827341217 3.53439448052669 0.000469157283870436 -196.047214996163 113.014230269251 -1.73471265104483 0.083757618246 EIF2AK4 other 0.0814589681301462 1 1 3.53439448052669 -1.73471265104483 0.523396664605866 46.9413896059944 43.3197686850792 1.08360203738028 0.27936737815232 3.57326454166195 90.2723180265192 0.0395831703425654 0.968450441047572 MYO5C other 1 1 1 1.08360203738028 0.0395831703425654 0.452489515933578 -60.0758788864053 47.7339096538544 -1.25855768618262 0.209113334877669 -48.969823206665 94.6210469574462 -0.51753626472436 0.605141678202707 CGNL1 other 1 1 1 -1.25855768618262 -0.51753626472436 0.0885913741205223 -0.770725019787867 19.3641024174637 -0.0398017425838847 0.968276321197647 -84.3626741179156 40.3251541588846 -2.09206079623451 0.0372308278791844 TMOD2 other 1 1 1 -0.0398017425838847 -2.09206079623451 0.00125785964111085 47.6383645456647 22.3630923273512 2.130222593921 0.0339157253590251 -88.1340002695086 45.2784393219706 -1.94648935761227 0.052470875017262 TTBK2 other 1 1 1 2.130222593921 -1.94648935761227 0.00450214937876777 21.6797085147813 15.3844169985947 1.40919922521352 0.159747281738837 -68.9348529981814 31.1487508694318 -2.21308563181683 0.0275970399744852 ELL3 other 1 1 1 1.40919922521352 -2.21308563181683 0.000250632731912865 55.736392955025 34.2859543289892 1.62563341303582 0.105015143940272 -191.80687253691 68.4534500284039 -2.80200446372422 0.0053889935733955 INO80 essential 1 1 1 1.62563341303582 -2.80200446372422 0.00156939891269774 57.4136152761405 30.2146858906406 1.9001890499191 0.058309777005716 -130.336511699552 59.3918641302037 -2.19451794632708 0.0289187891385125 ICE2 other 1 1 1 1.9001890499191 -2.19451794632708 0.776094601937847 2.44916582566244 15.3541685815109 0.159511458576251 0.873366878440524 21.4288340024671 30.6552882161858 0.69902569016307 0.485045314993756 DLL4 other 1 1 1 0.159511458576251 0.69902569016307 0.331120855798301 -29.2639319857501 30.9815659074815 -0.944559486539166 0.345598676481103 -86.7153580366412 61.2873915688423 -1.41489718875107 0.158074034588057 ALDH1A2 other 1 1 1 -0.944559486539166 -1.41489718875107 0.0018068942370114 71.7164883401079 33.1806385157384 2.16139566772023 0.0314084135216479 -124.205424231378 65.6375727195635 -1.89229155017729 0.0593574452113291 MINDY2 other 1 1 1 2.16139566772023 -1.89229155017729 0.00500220122500207 121.162063725867 59.9899646251119 2.01970553713493 0.0442470969592514 -187.924176848857 119.985422710965 -1.5662250680364 0.118284255400374 IVD other 1 1 1 2.01970553713493 -1.5662250680364 0.00287720467715711 70.6505958975329 30.0773179756541 2.34896595350425 0.0194334712429579 -83.1556446056013 60.1573902214021 -1.38230139804199 0.167843203238473 KNSTRN other 1 1 1 2.34896595350425 -1.38230139804199 0.00969332897949182 -13.4974845853042 79.0478746987075 -0.170750758787002 0.864528339329495 -473.857796687121 162.618075191521 -2.91393066932469 0.00382206454639304 DUT essential 1 1 1 -0.170750758787002 -2.91393066932469 0.650380703627396 1.61744454521505 19.3185829809215 0.0837248025288599 0.93332775181246 -31.2538232250668 38.570419887247 -0.810305496191931 0.418368686740321 CHAC1 other 1 1 1 0.0837248025288599 -0.810305496191931 9.69178055167182e-08 157.492107412117 59.6031506857807 2.64234533913137 0.0086381779303246 -447.690920472968 116.001098312338 -3.8593679455305 0.000137519255269678 CLN6 other 0.00107094175095974 1 1 2.64234533913137 -3.8593679455305 6.59449215707259e-07 490.172308219179 123.461789274393 3.97023492936568 8.88849850608146e-05 -556.363072602742 257.431665911314 -2.16120682214134 0.0314278277355748 ARPP19 other 0.00691168722982778 1 0.926537084273932 3.97023492936568 -2.16120682214134 0.0154727384881522 56.5579185762914 57.6393437853198 0.98123807215682 0.327216622822165 -246.964831640358 112.591950738824 -2.19345015358366 0.0289940434824744 VPS13C other 1 1 1 0.98123807215682 -2.19345015358366 0.0300119947254222 -9.84484137985048 17.9067406447304 -0.549784105056976 0.582850961473272 -91.4745217891774 34.8505332030787 -2.62476677920947 0.00908692199435355 CALML4 other 1 1 1 -0.549784105056976 -2.62476677920947 0.835848730356782 23.5942109973195 218.501343228669 0.107981995207358 0.914077646963198 251.276316881811 428.978665843974 0.585754809944799 0.558453175153004 ISLR other 1 1 1 0.107981995207358 0.585754809944799 0.242976997914287 -0.318989519740106 4.79725212112369 -0.0664942162067118 0.947025886301191 -14.8525576896421 9.33652849771747 -1.59080087350166 0.112641779717561 THAP10 other 1 1 1 -0.0664942162067118 -1.59080087350166 0.981871197255926 -7.24385923332073 61.8296651943202 -0.117158312446857 0.906808098483572 -22.3832094331076 121.596029563728 -0.184078456454671 0.854068500010438 LOXL1 other 1 1 1 -0.117158312446857 -0.184078456454671 0.0458155463533158 -24.4803822744833 10.1494637456698 -2.41198775501097 0.0164282706149782 -41.7044118323419 41.6641662000876 -1.00096595314211 0.317599565442699 ACKR4 other 1 1 1 -2.41198775501097 -1.00096595314211 2.73780447855994e-10 175.627042778819 26.4348426710889 6.64377106245832 1.31545008371031e-10 -99.291213747007 109.306968209227 -0.908370393705841 0.36436615236247 ANAPC13 essential 3.3820098723651e-06 1 1.78348722349444e-06 6.64377106245832 -0.908370393705841 3.54542558793754e-16 231.311217251637 26.7815292938979 8.63696821466952 2.78284370647965e-16 -64.2762065426117 107.460651550664 -0.598137137781153 0.550171525566343 MBD4 other 4.95331408890753e-12 1 4.04625474922141e-12 8.63696821466952 -0.598137137781153 7.54257027119154e-17 645.781761808289 108.469418350318 5.95358370709285 6.97495102030839e-09 -818.002115586312 227.217321766683 -3.60008695299328 0.000369217203902886 COPB1 essential 1.06101336004851e-12 1 9.05906638517653e-05 5.95358370709285 -3.60008695299328 6.18997604374102e-13 455.178106365856 107.644896970042 4.22851541669026 3.0838710606404e-05 -896.787513171776 222.563824701943 -4.02934984772458 7.012742121264e-05 PSMA1 essential 8.18995730347374e-09 1 0.334476655237058 4.22851541669026 -4.02934984772458 2.92077639801493e-07 389.24760287069 69.3819695868124 5.61021264153728 4.756119595148e-08 -208.538164523818 441.102880525804 -0.472765365474913 0.636739911061963 SUMF2 other 0.00313925047258644 1 0.000599936925731968 5.61021264153728 -0.472765365474913 3.81153195212796e-08 1469.83309607197 287.590048422569 5.11086215998783 5.54505524057327e-07 -365.866745193877 487.329680522785 -0.750758182430817 0.453353366827988 PALLD other 0.000429940804200034 1 0.00669121815879976 5.11086215998783 -0.750758182430817 3.57365135911111e-08 361.512663416784 98.6240815226155 3.66556177594298 0.000289397162131166 -464.313154606981 168.368051235354 -2.75772720061919 0.00615918690463021 SPCS3 essential 0.000403751130552373 1 1 3.66556177594298 -2.75772720061919 0.0185692850583255 21.7601827658317 21.9716692961683 0.99037458067087 0.322748793452625 -90.168584777446 46.6765464286695 -1.93177498500752 0.0542811465127167 BBOX1 other 1 1 1 0.99037458067087 -1.93177498500752 0.000889451653037696 25.8164570670794 16.1020030871448 1.60330717410496 0.109856478334406 -78.7992617968836 33.5045884069278 -2.35189463723095 0.019285701192031 SERGEF other 1 1 1 1.60330717410496 -2.35189463723095 0.663831009096816 126.529516114011 140.223598163336 0.902341102149056 0.367554385967386 141.625885306026 294.494252022965 0.480912222677208 0.63090752775376 CSRP3 other 1 1 1 0.902341102149056 0.480912222677208 0.00851969246358696 -36.5316542638821 19.9656378595612 -1.82972637893398 0.0682210971433106 -128.818283315668 41.9313558104818 -3.07212301691104 0.00230791964831917 E2F8 other 1 1 1 -1.82972637893398 -3.07212301691104 4.74927588554101e-15 260.644769344384 56.2307424548629 4.63527170308317 5.20988543018138e-06 -490.709565236766 105.430568677523 -4.6543385983024 4.77832798619693e-06 DCTD other 6.53452869091587e-11 0.0708864956752315 0.0596062992067051 4.63527170308317 -4.6543385983024 6.10223817300925e-05 336.620959650434 75.5516629711883 4.45550695262399 1.15865604820865e-05 -28.4648932285624 144.212859427398 -0.197381102778097 0.843654630401071 SOX15 other 0.538949675440177 1 0.129363947782496 4.45550695262399 -0.197381102778097 0.000113636695723442 69.6243612170925 20.6369316986766 3.37377485343702 0.000832567753169523 -100.438921724614 39.3917329286186 -2.54974620960745 0.0112460618648382 PIMREG other 0.973411935567005 1 1 3.37377485343702 -2.54974620960745 4.09464374352316e-08 155.877694123432 27.4833517449942 5.67171339106494 3.16314082692924e-08 -87.5218480634579 51.4838116109387 -1.69998773060661 0.0901049086632054 RPAIN essential 0.000460852153333531 1 0.00040146583375386 5.67171339106494 -1.69998773060661 0.139556115330378 5.35683381402112 2.70530368216611 1.98012291534382 0.0485460274226914 -1.02545436172348 6.03874324540207 -0.169812545433898 0.865264863086667 USP6 other 1 1 1 1.98012291534382 -0.169812545433898 0.000217877368715447 216.590466074584 58.5101925313062 3.70175616767448 0.000252047913426372 -239.549052646452 131.116560087421 -1.82699311579509 0.0686321426113992 PLD2 other 1 1 1 3.70175616767448 -1.82699311579509 0.0364494627561173 350.06167989799 192.094237874009 1.82234346939437 0.0693360831999499 -642.728628210633 366.669087534207 -1.75288468556999 0.0805793957581498 CD68 other 1 1 1 1.82234346939437 -1.75288468556999 0.00641388036688223 315.165881874369 110.553433168526 2.85080139839651 0.00464407499462299 -280.947616415293 211.024166639837 -1.331352806121 0.184020607358513 TXNDC17 other 1 1 1 2.85080139839651 -1.331352806121 0.00384357854684143 7.34447854384606 2.50338393036436 2.93382028012663 0.00359236845299191 8.4846614453898 4.79525085618764 1.76938844282598 0.0777904724526007 ATP1B2 other 1 1 1 2.93382028012663 1.76938844282598 4.4504576295184e-18 251.267468446572 27.6355660153393 9.09217738862683 1.04777732780183e-17 -126.730453042096 52.9781511793219 -2.39212675831468 0.0173277740130521 FXR2 other 6.34946790003391e-14 1 1.53625111802304e-13 9.09217738862683 -2.39212675831468 1.62291923306318e-07 936.506262124186 166.157189828128 5.63626685726269 3.81574729284549e-08 -348.05457476116 370.893890532173 -0.938420889763803 0.3487359052477 KIF1C other 0.00176963113173209 1 0.00048280650496374 5.63626685726269 -0.938420889763803 0.00040259276482542 179.107233258901 54.2634935786404 3.30069484006467 0.00107335205840196 -219.046453763033 103.578045323506 -2.11479617209308 0.0352201196398689 MPDU1 other 1 1 1 3.30069484006467 -2.11479617209308 2.94148198688409e-10 165.192798960263 24.1075694600627 6.85232077144592 3.75714830032927e-11 138.344693363104 136.510285498573 1.01343787288871 0.311619101328916 PHF20L1 other 3.62978877181497e-06 1 5.14541459730094e-07 6.85232077144592 1.01343787288871 0.4377210013853 -2.17381803640033 2.20590954807018 -0.985452027397079 0.325148919404746 -11.5362624750261 12.4910701881394 -0.923560775919752 0.35641308549509 LRRC6 other 1 1 1 -0.985452027397079 -0.923560775919752 0.000842187193100633 126.598780805115 38.9906421546968 3.24690166175848 0.00129034717874927 -126.061528235425 98.5307870485972 -1.27941257764691 0.201678692346849 CCNT1 other 1 1 1 3.24690166175848 -1.27941257764691 0.000428442044984877 60.7169436906378 17.776831960171 3.41550979537152 0.000720048553915898 -66.7422205322363 49.0941674465057 -1.35947351800925 0.174968963301791 PUS7L other 1 1 1 3.41550979537152 -1.35947351800925 3.06221985807105e-12 330.992445760356 57.6091785996923 5.7454810814144 2.14003851899789e-08 -373.11437286215 127.998025404636 -2.91500100632519 0.00380852070621587 KRI1 essential 3.98731647719431e-08 1 0.00027351832311312 5.7454810814144 -2.91500100632519 6.17503139048354e-08 1017.12618954564 228.12053458662 4.45872262831919 1.14353943943501e-05 -1162.06524814959 506.845934815902 -2.29273861804116 0.0225135325495816 ILF3 essential 0.000688577750352819 1 0.127710484596102 4.45872262831919 -2.29273861804116 7.00932017423933e-05 427.436300797123 174.811684281559 2.44512432080155 0.0150207233490956 -1069.1661546432 388.402524555656 -2.75272709894551 0.00624850624718765 SLC44A2 other 0.614927658886016 1 1 2.44512432080155 -2.75272709894551 7.38969672672746e-07 212.245645149563 56.9601636011421 3.72621200029888 0.000229857736194587 -327.3441456631 126.556021885549 -2.58655527240839 0.0101366333586719 AP1M2 other 0.00772075514008485 1 1 3.72621200029888 -2.58655527240839 0.000285218735018206 17.5918165622927 17.6034804459006 0.999337410369284 0.318388700724665 -135.137023840903 39.1120094417807 -3.45512863618163 0.000624443685584204 CDKN2D other 1 1 1 0.999337410369284 -3.45512863618163 1.91072311389965e-14 193.059914325378 121.582602849694 1.58789094656944 0.113298546163472 -1214.57631553506 226.083318649595 -5.37225091523682 1.49947162164762e-07 MTUS1 other 2.60183166419716e-10 0.00226375230720142 1 1.58789094656944 -5.37225091523682 0.237406417279987 297.207296827349 175.352919676046 1.69490931417864 0.0910684864458459 201.972450562796 425.818571158183 0.474315739713868 0.635599276870905 KLK14 other 1 1 1 1.69490931417864 0.474315739713868 0.815604453910547 2.11456286108412 3.4902873266387 0.605842059175264 0.545050456392451 -0.618395266136157 8.51883555786139 -0.0725915252073961 0.942176663572087 SIGLEC9 other 1 1 1 0.605842059175264 -0.0725915252073961 0.81167016841378 633.426365509926 1122.04176296299 0.564530115026407 0.572790138678274 -521.200149629531 2724.71209015161 -0.191286320310096 0.84842296934155 KLK10 other 1 1 1 0.564530115026407 -0.191286320310096 0.298572503200758 -151.059504892924 256.32558400486 -0.589326677941206 0.556059275814456 -953.931044944103 622.448683112212 -1.53254568742036 0.126378936352871 KLK8 other 1 1 1 -0.589326677941206 -1.53254568742036 4.0470115347107e-21 166.752929337213 17.8738875293393 9.32941583432779 1.82627845432451e-18 -112.987077039577 49.0118282616329 -2.30530223105397 0.0217890292817283 NGDN other 5.91713556490051e-17 1 2.6912039302926e-14 9.32941583432779 -2.30530223105397 0.0471816491690656 13.8951693033933 9.65204078653436 1.43960946816331 0.150955432212917 -42.355862980141 26.2798642703956 -1.61172304941678 0.108008040668468 RIPK3 other 1 1 1 1.43960946816331 -1.61172304941678 0.831111485674004 -2.88698366677191 4.99297286542438 -0.578209364357627 0.563529456747971 0.582698547515172 13.5944980042127 0.0428628219544852 0.965837617714855 ADCY4 other 1 1 1 -0.578209364357627 0.0428628219544852 1.36640162318062e-13 86.6422152163363 12.2056997353714 7.09850455891951 8.26776001449122e-12 -68.5310036778611 33.859223414521 -2.02399809466601 0.043806148686436 RAB2B other 1.83166137587363e-09 1 1.14533279480747e-07 7.09850455891951 -2.02399809466601 4.11450099968376e-11 297.249228429871 47.8885695239565 6.20710184882784 1.67154745816298e-09 -264.683242929816 131.346425003137 -2.01515376549833 0.0447244250548336 BCL2L2 other 5.21430711689923e-07 1 2.21078866816636e-05 6.20710184882784 -2.01515376549833 3.81710258324797e-08 474.191157411749 99.1476686069192 4.78267582157405 2.64377078178858e-06 -674.568003571244 272.284793317093 -2.4774354651002 0.0137489925654316 AJUBA other 0.000430531000364539 1 0.0308025733786188 4.78267582157405 -2.4774354651002 4.29071077174289e-20 181.177268244468 18.3609195850977 9.86754870336217 3.63330472368832e-20 -3.28339330877365 57.928394280246 -0.0566802057880156 0.954836222982138 DTD2 other 6.23182832487938e-16 1 5.40127080223505e-16 9.86754870336217 -0.0566802057880156 1.00970189749772e-09 108.011680427248 16.9125078377507 6.38649699166156 5.97270590304089e-10 -32.0039860343842 50.1461186120002 -0.638214619999033 0.523790438284792 PARP2 other 1.22002280274649e-05 1 7.99267503944932e-06 6.38649699166156 -0.638214619999033 0.000619877233556971 71.9682933164829 22.3629397861267 3.21819465619318 0.00142519971836403 -97.1524915615113 70.5583749639521 -1.37690942586399 0.16952424740905 HEATR5A other 1 1 1 3.21819465619318 -1.37690942586399 0.557833675889815 -58.3629161840491 55.9696641844477 -1.04275980630712 0.297872050553864 7.777397814467 180.904953407258 0.042991624430307 0.965735887912539 FOXA1 other 1 1 1 -1.04275980630712 0.042991624430307 1.09133878264765e-29 553.652318873768 46.2283805730619 11.9764593094224 1.94963831518775e-27 -286.558799695556 149.214289402517 -1.92045145838909 0.0557151572497448 SNX6 other 1.64835809731101e-25 1 2.94999773471059e-23 11.9764593094224 -1.92045145838909 4.66540220880511e-19 142.256786251161 16.7332207929755 8.50145874552014 7.94487609888599e-16 -154.131674414806 53.4838446497772 -2.88183610254818 0.0042287363346382 EAPP other 6.7172461002376e-15 1 1.15184813681649e-11 8.50145874552014 -2.88183610254818 8.87073157575242e-05 479.642991494269 114.732609935079 4.18052889902596 3.78199657253521e-05 -108.42950050274 365.138305175138 -0.296954603135193 0.766698765643136 EGLN3 other 0.768382769091675 1 0.407812690416472 4.18052889902596 -0.296954603135193 0.110769101813487 37.2320444778927 22.8703429677658 1.62796179009509 0.104565497995888 -65.417570144231 68.3962259248426 -0.956449997929934 0.339602420273074 MIS18BP1 essential 1 1 1 1.62796179009509 -0.956449997929934 4.01689929010218e-06 3.98285705838051 1.43589877725917 2.77377286021716 0.00586728881536369 -13.501853906026 3.90073905462835 -3.46135789062989 0.000610684673813113 NRL other 0.0396548297918888 1 1 2.77377286021716 -3.46135789062989 0.685190320461894 -29.5980540815061 98.8116784950951 -0.299540039520484 0.764723098270841 204.435379229312 276.574130958276 0.739170285091319 0.460347146823432 RNASE1 other 1 1 1 -0.299540039520484 0.739170285091319 1.32006721310653e-12 485.2569895613 74.0802785325818 6.55042069459655 2.28910452411722e-10 -478.914491299274 201.700314783726 -2.37438643471028 0.018167637736125 NEDD8 other 1.7348323314646e-08 1 3.08823091348654e-06 6.55042069459655 -2.37438643471028 5.8921339974719e-16 449.912527876762 59.8393492553828 7.51867347281172 5.61613189804358e-13 -475.910029334489 164.015511079851 -2.90161598864142 0.00396980638823918 DAD1 essential 8.21186715227658e-12 1 7.90358242011673e-09 7.51867347281172 -2.90161598864142 1.01082247199425e-10 175.177653328273 26.6505520413503 6.5731341345752 2.00958897699815e-10 -97.4656761560054 79.5740751740154 -1.2248420850995 0.221538399564577 TEP1 other 1.26403350122881e-06 1 2.71435183123141e-06 6.5731341345752 -1.2248420850995 0.00443354323007023 4.93729920346772 32.8638222098151 0.150235087444976 0.880673794250977 -140.256806883637 46.5475499305885 -3.01319418729423 0.00279149206737966 EPB41L4A other 1 1 1 0.150235087444976 -3.01319418729423 0.734269207412839 -6.32139377667575 8.23494521219296 -0.767630338003472 0.443272869273156 -1.76082994411101 12.1698133188273 -0.144688328241397 0.885048039049058 CDO1 other 1 1 1 -0.767630338003472 -0.144688328241397 5.09102671792756e-10 398.064483014276 87.3114590229985 4.55913218572401 7.32198020310163e-06 -359.070720776379 123.665910569945 -2.90355457798769 0.00394594768493822 REEP5 other 6.22938029205616e-06 1 0.0829637352377964 4.55913218572401 -2.90355457798769 8.52472816356964e-11 165.608604374989 35.2449200650052 4.69879358697773 3.95534290242836e-06 -242.973388691968 94.8598405370517 -2.56139360256529 0.010902922318629 ITFG1 other 1.06883041714836e-06 1 0.0455774162646819 4.69879358697773 -2.56139360256529 0.452228935630034 -9.39444232154736 12.4042033230724 -0.757359588267412 0.449395272900496 -34.4996300393958 30.6007480559693 -1.12741132917062 0.260418560934158 QRICH2 other 1 1 1 -0.757359588267412 -1.12741132917062 0.7940515562634 -18.7955635541791 30.7664071454698 -0.610911877532852 0.541692960309971 -30.0824218117368 75.2982959418308 -0.399509994688008 0.689784807771243 FOXJ1 other 1 1 1 -0.610911877532852 -0.399509994688008 8.50350392410878e-11 418.90158831893 67.3820136339078 6.21681611646184 1.58181876912e-09 -342.97753442217 162.288436476907 -2.11338245575478 0.0353417814210448 SEC14L1 other 1.066254357044e-06 1 2.09353714093033e-05 6.21681611646184 -2.11338245575478 8.76131851835655e-06 199.295476382144 55.991994356235 3.55935663077433 0.000428295970540054 -361.56880096917 134.975303742645 -2.67877745738263 0.0077721590802443 RHBDF2 other 0.0840473285465944 1 1 3.55935663077433 -2.67877745738263 2.06761365693751e-32 179.227654646409 31.5205083387264 5.68606485404323 3.18864659855769e-08 -564.247877189371 73.8511717425705 -7.640337504139 3.23063581075522e-13 ASH2L other 3.13470906528296e-28 4.95353388863098e-09 0.000404607366890986 5.68606485404323 -7.640337504139 2.44774643955204e-40 83.9601522985501 11.2899572353341 7.43671127785861 1.00497359004287e-12 -182.122002755007 25.0972893139021 -7.25664036769596 3.16713373527179e-12 TTI2 essential 3.73942223570364e-36 4.85331573593048e-08 1.41078192570218e-08 7.43671127785861 -7.25664036769596 0.418764914114849 3.3874350389253 2.57170795451689 1.31719273682522 0.188716422980885 2.8866380461352 5.08821597553171 0.567318301742008 0.570895709149977 CHRNA10 other 1 1 1 1.31719273682522 0.567318301742008 0.167195361244371 -26.6513318814053 38.9144395119789 -0.684869992106691 0.493921719402766 -133.213361063661 72.1040170428936 -1.84751649806715 0.0655951315906973 CDKN1C other 1 1 1 -0.684869992106691 -1.84751649806715 2.17212787287191e-15 46.0193805894282 12.8469296738626 3.58213065360324 0.000393777455329339 -102.810112854339 19.6581868131632 -5.22988787478086 3.07072663304381e-07 SGO1 other 3.00535612490558e-11 0.00462727796333372 1 3.58213065360324 -5.22988787478086 0.0224235738828074 16.5507210004374 6.45696363503104 2.56323590094957 0.0108269490243639 3.46126101578244 16.485489299658 0.20995803963515 0.833834035705834 CDH15 other 1 1 1 2.56323590094957 0.20995803963515 4.1399190641504e-08 139.859551785641 52.2187630519045 2.6783390415936 0.00778333084218694 -283.550300821606 86.5327422297229 -3.27679781681771 0.00116593468737995 KLF16 other 0.000465823693098204 1 1 2.6783390415936 -3.27679781681771 0.00042062456555051 216.164201988229 61.6708000980984 3.50513049359471 0.000522572340448147 -125.26781130677 166.372503625475 -0.752935783119328 0.452050834878778 TMEM8A other 1 1 1 3.50513049359471 -0.752935783119328 1.87400181925795e-07 82.9507824306536 27.9516139761508 2.96765626848703 0.00322922797531587 -143.692029444742 49.6511331152491 -2.8940332360836 0.00406691139567098 DOHH essential 0.00203703997753339 1 1 2.96765626848703 -2.8940332360836 3.90759457260825e-10 183.88963524174 48.4643890852701 3.79432483752549 0.00017711614108393 -468.228149652427 110.302002271058 -4.24496509593537 2.87029831861407e-05 MAU2 essential 4.80087069190649e-06 0.417484890442416 1 3.79432483752549 -4.24496509593537 0.00197463515184903 156.341085800027 43.9939687296314 3.55369361561432 0.000437640701596922 114.172677670168 71.9224967661576 1.58744040882477 0.11340984414947 SHC2 other 1 1 1 3.55369361561432 1.58744040882477 0.819161232151146 9.2713893704812 22.9697383367531 0.403634958072046 0.686750760688676 26.430236997342 41.9770754143559 0.629635026653215 0.529382680359051 INS-IGF2 other 1 1 1 0.403634958072046 0.629635026653215 1.70148939711118e-09 80.7744564107448 29.8044602217812 2.71014659583449 0.00709022408562729 -187.404631911447 49.3895589044092 -3.79441801199639 0.000177149569684496 ABHD17A other 2.03804399985977e-05 1 1 2.71014659583449 -3.79441801199639 0.78184215130106 9.53891498121551 15.5186507571516 0.614674247812403 0.539210808805387 -15.9885981209609 79.1689121099548 -0.201955511258699 0.840081044485073 LBP other 1 1 1 0.614674247812403 -0.201955511258699 0.00574440686333753 23.1223641595417 7.16851681282235 3.22554368822608 0.00138727583321665 10.2536697364001 18.7077698200549 0.548096851470137 0.584007535120852 SYT5 other 1 1 1 3.22554368822608 0.548096851470137 4.0196778957004e-06 38.2680808989905 7.64659087460444 5.00459374988728 9.25733004060798e-07 8.42207672854727 19.9554058008704 0.422044874085193 0.673275665789727 TNNI3 other 0.0396742208305629 1 0.011055103534494 5.00459374988728 0.422044874085193 0.485436286730567 4.64207679233169 13.8056738244877 0.336244130590559 0.736907153997783 41.5149239440568 35.1262507639343 1.18187745749063 0.238131847085324 CBFA2T3 other 1 1 1 0.336244130590559 1.18187745749063 0.297283021821868 90.564015455857 58.7077141660353 1.54262547507346 0.123916181247455 95.7205284270502 96.661475155063 0.990265545539178 0.322797225331936 GAMT other 1 1 1 1.54262547507346 0.990265545539178 6.92331570515088e-06 42.3648500921721 11.6269367578714 3.64368113239211 0.000314063825607262 -64.6432631033979 26.8606626576955 -2.40661460691394 0.0166746720395598 ERMARD other 0.0670453892886811 1 1 3.64368113239211 -2.40661460691394 0.00670869093365325 49.6187915381392 44.3280447516338 1.11935439102151 0.263836405306554 -269.643948834726 102.413952390181 -2.63288294750528 0.0088811248443602 PHF10 other 1 1 1 1.11935439102151 -2.63288294750528 0.018582495246915 30.1337320183085 10.624788586267 2.83617238815063 0.00486133708304138 14.0818189661436 51.0331299092915 0.27593484842441 0.782779044668041 CRACR2A other 1 1 1 2.83617238815063 0.27593484842441 7.05937519702903e-08 409.048689242632 103.167814781589 3.96488662775893 9.06295802684582e-05 -376.730518264998 180.967905821642 -2.08175320676085 0.03815945686311 SH3BP4 other 0.000784367178141896 1 0.943725819335455 3.96488662775893 -2.08175320676085 1.83022403383637e-06 238.409846848169 54.7730128588704 4.35268820180592 1.81498995601513e-05 -164.470009663693 115.564065772391 -1.42319334790128 0.155660427113217 DOCK6 other 0.0185401694627624 1 0.200048192951987 4.35268820180592 -1.42319334790128 7.09785453548379e-09 242.491464580793 55.5146878892954 4.36805958567862 1.6986057940293e-05 -346.554222089551 117.128905417393 -2.95874208722938 0.00332074306138864 ECSIT other 8.29597238107346e-05 1 0.187644982066416 4.36805958567862 -2.95874208722938 1.40776861615366e-08 126.602060744661 40.7355371614119 3.10790208173783 0.00205432281623237 -353.157418697645 85.9467838281001 -4.10902424695711 5.06031760332538e-05 ELOF1 other 0.000162203099953224 0.730001417455719 1 3.10790208173783 -4.10902424695711 0.000614117364070088 7.2035952986891 2.38340904302001 3.02239152770917 0.00271165446229126 -6.94503247371999 5.02868885667788 -1.38108216110792 0.16822343824854 ANGPTL8 other 1 1 1 3.02239152770917 -1.38108216110792 0.0326854940368024 570.062836774654 268.5319158181 2.1228867154875 0.0345355881332629 -458.61579060986 566.568066313034 -0.809462830466819 0.418854226666883 PRKCSH other 1 1 1 2.1228867154875 -0.809462830466819 0.000625342853230099 163.83240322393 43.8012123243294 3.74036229889758 0.000217923493367146 15.6790515413843 92.4149671116642 0.169659223299181 0.865386021300465 CNN1 other 1 1 1 3.74036229889758 0.169659223299181 6.19814281574562e-23 219.338660981308 23.8126724475835 9.21100567204783 5.15601045097729e-18 -212.067832790779 57.7165893881526 -3.67429598732162 0.000281208677634666 CDC16 essential 9.16209471023517e-19 1 7.57572615562094e-14 9.21100567204783 -3.67429598732162 0.167748512997037 57.3987066599329 30.3578741309436 1.8907353793073 0.0595628906328753 45.7332646877066 149.861568819246 0.305170064934174 0.760435028553401 THEM6 other 1 1 1 1.8907353793073 0.305170064934174 0.327047838017003 -2.770034982847 2.8152522132471 -0.983938479761302 0.325889105202471 5.81587337776843 6.7537071377803 0.861137929010036 0.389806859205246 EXOC3L2 other 1 1 1 -0.983938479761302 0.861137929010036 1.92786382392267e-55 1216.34088297351 62.7035031862903 19.3982922989135 6.46624438072768e-56 49.5454321938907 259.792253121654 0.190711738316115 0.84887275506427 NECTIN2 other 2.95734310589738e-51 1 9.92115875335047e-52 19.3982922989135 0.190711738316115 0.000208974810049576 1080.07119940965 261.611056697971 4.12853804056373 4.66609431202531e-05 24.1672439238942 1080.24414608262 0.0223720202618397 0.982165186609014 APOE other 1 1 0.49945873515919 4.12853804056373 0.0223720202618397 2.11435027986456e-29 544.966952050122 43.7526734463888 12.4556263451623 2.73326920026473e-29 -183.374793319504 180.663500856891 -1.01500741682605 0.310871507892079 TOMM40 essential 3.19140031242756e-25 1 4.14718935756168e-25 12.4556263451623 -1.01500741682605 0.444816474407689 88.4026397705595 71.2443947453038 1.24083642069802 0.215577943897547 -30.1924128041383 294.182292354966 -0.102631645713426 0.918319811282821 APOC1 other 1 1 1 1.24083642069802 -0.102631645713426 0.908395931327287 -6.95690471446328 17.9518850819703 -0.387530595405289 0.698621070300756 -8.9171883287636 34.0743263382935 -0.261698154799389 0.79372252705257 GADD45G other 1 1 1 -0.387530595405289 -0.261698154799389 1.2413555025712e-31 452.649004029217 74.3598834395473 6.08727425450054 3.28403493033642e-09 -746.456115829109 137.506740310153 -5.42850564376293 1.12497099907077e-07 XPO7 other 1.8802811797446e-27 0.00170005617379575 4.30996744257352e-05 6.08727425450054 -5.42850564376293 7.476361981747e-05 39.1508829378324 12.1512938821185 3.22195177876864 0.00140422488476739 -74.2871138322448 35.8457374002623 -2.0724113721734 0.0390275315291704 FAM98C other 0.653583564444323 1 1 3.22195177876864 -2.0724113721734 1.99228554252327e-06 114.88396992955 48.0515743894237 2.39084715515246 0.017390841464434 -268.883867143833 88.0740832831351 -3.05292836576501 0.00245746098143671 SAFB2 other 0.0201320454071976 1 1 2.39084715515246 -3.05292836576501 0.0020630959518137 1310.92595279625 941.993888151991 1.39165016810039 0.165004086069582 -3996.15519503574 1729.69602686332 -2.31032223753354 0.021512119574544 RPL36 essential 1 1 1 1.39165016810039 -2.31032223753354 0.119282167549019 27.1732337603987 13.1450108215688 2.06718991176575 0.0395250937826359 21.0415908372326 21.7828567080209 0.965970217739377 0.33479311980048 ATP8B3 other 1 1 1 2.06718991176575 0.965970217739377 0.48338442712807 -42.5422706115244 35.2682715547904 -1.20624767634086 0.228615846785221 -37.82609491199 64.1053077786404 -0.590061825186237 0.555566932610982 KIF1A other 1 1 1 -1.20624767634086 -0.590061825186237 4.77378505275705e-11 114.147258824767 21.9724313233163 5.19502175909129 3.6642639181868e-07 -163.337566969599 51.2592023800742 -3.18650231344787 0.00158301354966478 GTPBP3 other 6.03454168519019e-07 1 0.00445611135090697 5.19502175909129 -3.18650231344787 0.980141119563041 -21.101978501986 109.96254143158 -0.191901516891695 0.847941829072781 -28.5165037748662 256.530198343926 -0.111162365908416 0.91155772176585 PLVAP other 1 1 1 -0.191901516891695 -0.111162365908416 0.0577345701408492 -688.063608868194 633.071492091366 -1.08686557120928 0.27791935702597 -3490.51500620301 1476.88434004713 -2.36343152375197 0.0187077476776517 BST2 other 1 1 1 -1.08686557120928 -2.36343152375197 0.0108301040660446 54.0329234120641 32.2406026597939 1.67592783491751 0.0947321079016092 -144.714880645329 75.2298004600599 -1.92363770421217 0.0552896845831154 SLC27A1 other 1 1 1 1.67592783491751 -1.92363770421217 2.28968440022252e-05 158.12376684596 40.1812224000731 3.93526521596496 0.000102299310200042 -201.544886982023 138.202666141404 -1.45832850124475 0.145746339669702 NSUN5 other 0.21156683858056 1 1 3.93526521596496 -1.45832850124475 0.550876234748782 1.96053228509516 1.81139487017411 1.08233291226375 0.279922086439105 0.732303419761384 4.25030200759062 0.172294443654489 0.863315308190335 USHBP1 other 1 1 1 1.08233291226375 0.172294443654489 0.000557762190531134 595.312008979683 176.211555744547 3.37839369537548 0.000819476910859294 -372.870490162069 411.169738894196 -0.90685294877213 0.365169060765592 COLGALT1 other 1 1 1 3.37839369537548 -0.90685294877213 1.71676609040547e-08 84.6574475974042 36.5899945108977 2.31367751564408 0.0213227526198288 -407.249575138501 85.3603274995617 -4.77094672745477 2.79867241181919e-06 DDA1 other 0.000197222088465781 0.041652641505105 1 2.31367751564408 -4.77094672745477 1.90423666622478e-06 90.8385838643906 36.9193795260119 2.46045803127296 0.0144055762236211 -320.459494632493 86.6285510145701 -3.69923646279845 0.000254585122829125 MRPL34 essential 0.0192708750621948 1 1 2.46045803127296 -3.69923646279845 0.0039564897064939 159.426496808761 83.9078449739696 1.90001896554749 0.0583321763986757 -408.996486132354 195.789467741473 -2.08896061085577 0.0375035234442148 PGLS other 1 1 1 1.90001896554749 -2.08896061085577 1.04542702088165e-05 191.444718952171 91.9167805326702 2.08280487896468 0.0380677756590877 -451.695539279865 159.608400681474 -2.83002359118491 0.00495048666028807 LSM7 essential 0.0996291950900212 1 1 2.08280487896468 -2.83002359118491 1.18420219172168e-06 95.0671091581021 48.1391705333198 1.97483895349424 0.0491457239661218 -462.898956052781 105.272454444302 -4.39715173828016 1.49480157192096e-05 TULP4 other 0.0121996509791168 0.219122962427894 1 1.97483895349424 -4.39715173828016 1.57717217315767e-06 133.240802368126 53.3414139920426 2.49788658373404 0.0129952569509919 -464.314263393298 116.648905917173 -3.98044250601877 8.51607002118648e-05 SNX9 other 0.0160776931331693 1 1 2.49788658373404 -3.98044250601877 0.00441739570284995 10.7159524792732 7.51860137279137 1.42525876129735 0.155060102258966 -42.8121025380388 17.0487346248813 -2.51116012302508 0.0125274800694651 RTN4IP1 other 1 1 1 1.42525876129735 -2.51116012302508 3.68332521500747e-07 33.097244984818 12.469614297888 2.65423165417584 0.00834738637637866 -113.382408430842 28.2890816723859 -4.00799183741334 7.62864219814049e-05 QRSL1 essential 0.00393563299223549 1 1 2.65423165417584 -4.00799183741334 0.0111877475565976 18.8935726899671 10.059893241092 1.8781086674749 0.0612783154166555 -40.4701502966548 22.8222890230805 -1.77327306019685 0.0771375575315464 C6orf203 other 1 1 1 1.8781086674749 -1.77327306019685 9.96070030358192e-07 34.5847069258629 15.8443970753623 2.18277203994347 0.0297814099121606 -149.110708373487 34.6306550598282 -4.30574322420071 2.21764560007611e-05 RSPH3 other 0.0103172933744502 0.323377081403098 1 2.18277203994347 -4.30574322420071 2.75124827240278e-15 351.393527273727 77.1034082302886 4.55743183523357 7.37783252676254e-06 -635.438313891089 140.665722961551 -4.51736429111998 8.8188408164191e-06 MLLT1 other 3.79864848970652e-11 0.129954438270752 0.0835687090306393 4.55743183523357 -4.51736429111998 0.117509841326798 1.1153660588507 6.13399408902973 0.181833572491611 0.855828824410165 -19.8667211088918 11.1277567575141 -1.78533028190759 0.0751577290838754 FUT5 other 1 1 1 0.181833572491611 -1.78533028190759 4.1582064533617e-05 55.3003525416563 106.862301059269 0.517491687840273 0.60517162465518 -1057.53928249475 246.92365069827 -4.28285941627768 2.44469774468852e-05 AFDN other 0.374404909060687 0.356119120468776 1 0.517491687840273 -4.28285941627768 4.04157004309858e-10 3195.04319872621 534.411182416236 5.97862339683919 6.0069217901019e-09 -2417.47121693044 1554.67069658355 -1.55497316714268 0.12094088125334 ACTN4 other 4.96304801292505e-06 1 7.82341493942872e-05 5.97862339683919 -1.55497316714268 0.327185634173452 -9.71166992648117 6.86489064750651 -1.4146867627103 0.158132655362043 -15.215546066106 13.6950298836172 -1.11102686123436 0.267390871651204 STK33 other 1 1 1 -1.4146867627103 -1.11102686123436 5.55123107188688e-13 286.365142533154 73.0011005306132 3.92275103322677 0.000107231979419814 -570.232474215202 132.252023670646 -4.31171076546458 2.16183682928824e-05 NDUFA10 other 7.35149530849979e-09 0.315433611761447 1 3.92275103322677 -4.31171076546458 9.44270581843799e-10 1187.82065889391 192.491047545607 6.17078390937884 2.0666244646494e-09 -1010.91420450501 841.584276923291 -1.20120376797053 0.230566062502234 ARPC1B other 1.14266183108918e-05 1 2.72773763089075e-05 6.17078390937884 -1.20120376797053 0.519101396985864 5.94354001730038 7.36211600338983 0.807314094828677 0.420090874454964 -10.1540200400939 17.9020538509624 -0.567198608865093 0.570980681020492 CACNG6 other 1 1 1 0.807314094828677 -0.567198608865093 0.000449443028186664 24.6481793592147 26.1380281898705 0.94300071834672 0.346394153625819 -117.31711885839 37.730965082307 -3.10930607267723 0.00204433062647642 ZSWIM6 other 1 1 1 0.94300071834672 -3.10930607267723 0.0645560075032534 35.5211558046643 22.0584280211142 1.61032126907065 0.108319884354223 -58.0100867467446 50.634145745573 -1.14567128352939 0.252792623555692 FCHO1 other 1 1 1 1.61032126907065 -1.14567128352939 0.58787422760892 10.1914020519549 17.7943411586133 0.572732755942571 0.567229106700063 -26.6088273990337 41.3077836136325 -0.644160133303598 0.519934486441868 UNC13A other 1 1 1 0.572732755942571 -0.644160133303598 5.84599276691723e-05 147.235651756242 40.4953658061911 3.63586422359795 0.000323039853947712 -130.225832255922 92.9553208546091 -1.40095081226826 0.162203867170826 MAP1S other 0.517311899944506 1 1 3.63586422359795 -1.40095081226826 0.0164454835906758 -258.507282315494 136.563400233885 -1.89294702587049 0.0592784959768792 -1015.91216495086 392.989784612808 -2.58508542646162 0.0101832889102284 KLHDC7B other 1 1 1 -1.89294702587049 -2.58508542646162 0.118049087965266 67.4536527886879 160.609380379724 0.419985760664845 0.674778587853385 -846.586542904672 455.990983879177 -1.85658614497735 0.0642918196304152 SCO2 other 1 1 1 0.419985760664845 -1.85658614497735 0.00167098072841467 851.783394783032 241.362836693945 3.52905777231612 0.000479374633778564 1189.86211931573 751.177276046358 1.58399642435709 0.11420113814877 PXDN other 1 1 1 3.52905777231612 1.58399642435709 0.00531030567021686 55.9855435014895 34.4427768891063 1.62546544030824 0.105057150177973 -180.262492300344 80.7017654533512 -2.23368709826481 0.0262009454252399 SSBP4 other 1 1 1 1.62546544030824 -2.23368709826481 0.0355331696273315 -135.518779081357 67.3563772810793 -2.01196656577646 0.045069187778548 -340.464208942198 157.820566518966 -2.15728669876042 0.0317345074679841 GDF15 other 1 1 1 -2.01196656577646 -2.15728669876042 0.0872213933626232 -16.6490967831148 27.8568598746549 -0.597665955819476 0.550489547983933 -144.685904285409 65.2705146019253 -2.21671156061548 0.0273522212844143 PGPEP1 other 1 1 1 -0.597665955819476 -2.21671156061548 0.0815266291051925 -4.82625460549099 8.20507272931508 -0.588203756957296 0.556813039766343 -43.206797722895 19.2289869471349 -2.24696172719243 0.025328040089765 KIAA1683 other 1 1 1 -0.588203756957296 -2.24696172719243 0.00518068966332679 151.009029621659 120.809320828662 1.24997830122585 0.212226575611842 -716.204493637189 283.122518220566 -2.52966276980919 0.011899909326821 LSM4 essential 1 1 1 1.24997830122585 -2.52966276980919 0.000148544679183877 730.6794792534 207.415334304145 3.52278428065478 0.000489587143832292 -614.706742331926 486.087922380058 -1.26459990884387 0.206940802703641 JUND other 1 1 1 3.52278428065478 -1.26459990884387 0.131928329951407 83.4200781249998 48.6904643201377 1.71327341584825 0.0876307713156784 -73.4158928571431 111.556216523715 -0.658106694049957 0.51094273719245 HRC other 1 1 1 1.71327341584825 -0.658106694049957 0.00905533595661721 81.9967655292426 54.809317196465 1.49603698282399 0.135629592826593 -293.668601404396 127.590175123219 -2.30165528905958 0.021996626374907 TRPM4 other 1 1 1 1.49603698282399 -2.30165528905958 0.00114698938389704 12.3883578452069 4.04939317847076 3.05931217325885 0.00240596520671153 28.844655432906 10.3293883116812 2.79248437202098 0.00554517724934243 SULT4A1 other 1 1 1 3.05931217325885 2.79248437202098 7.85815554490522e-09 21.5251943602531 8.61154805714813 2.49957315658082 0.0129347680569655 -63.1842953586924 15.4959619845558 -4.07746840252097 5.75063594018482e-05 ZNF557 other 9.16496681202296e-05 0.827746537230203 1 2.49957315658082 -4.07746840252097 8.11539717463383e-05 6.09774781604996 30.0147001414447 0.203158711808355 0.839140102728428 -208.439960328389 54.0748638088745 -3.85465529908891 0.000140074570001364 CRB3 other 0.705552630362665 1 1 0.203158711808355 -3.85465529908891 0.215207421949562 -47.6119325895754 116.606937635122 -0.408311319679445 0.683318209834736 -425.418809129008 243.868584817393 -1.7444592522959 0.0820391457097512 OLFM1 other 1 1 1 -0.408311319679445 -1.7444592522959 3.61333774666431e-06 159.612513420016 56.5089561213452 2.82455250239042 0.00503270495809993 -460.323891435617 117.682358407321 -3.91157942163556 0.000112076502768183 CAMSAP1 other 0.0357864970429634 1 1 2.82455250239042 -3.91157942163556 2.88808284400701e-09 261.464439937969 56.125859369445 4.65853784468396 4.68257535065663e-06 -460.566232340963 116.884542762576 -3.94035191870063 0.000100000095958942 UBAC1 other 3.43306407667113e-05 1 0.0536950915459796 4.65853784468396 -3.94035191870063 0.15589855416136 9.75713589868484 8.63423935642222 1.13005158832288 0.259308805253193 69.6287733178869 38.9510534618215 1.78759666631699 0.0747962668920936 ZBTB46 other 1 1 1 1.13005158832288 1.78759666631699 0.0150952814762032 222.763774020523 134.996027254061 1.65015058999688 0.0998963581183753 -1194.03700220218 610.780537139008 -1.95493623257093 0.0514636521537089 HELZ2 other 1 1 1 1.65015058999688 -1.95493623257093 0.0753379604945314 3.0528861452301 8.78990785061192 0.347317195710711 0.728584238610074 -85.6628957602674 40.2976008140989 -2.12575672073998 0.0342987181403821 SAMD10 other 1 1 1 0.347317195710711 -2.12575672073998 0.382659112376343 1002.74756125653 834.589313139562 1.2014862225882 0.230451114065359 1918.80965555703 1525.20755892194 1.25806461181802 0.209285590134034 TNNT3 other 1 1 1 1.2014862225882 1.25806461181802 0.190404985847226 899.292145665868 536.086258429922 1.67751389170037 0.0944184477046144 1520.56307162996 979.694804041624 1.55207832618591 0.121631897381589 TNNI2 other 1 1 1 1.67751389170037 1.55207832618591 6.17229901495505e-05 3532.58936898647 1067.20038901981 3.31014625306786 0.00103892361150141 7508.97582116541 2231.91393123802 3.36436621326176 0.000860462437167981 COL5A1 other 0.544643665079634 1 1 3.31014625306786 3.36436621326176 5.39882327840687e-05 263.551440401633 74.4759296184874 3.53874656888084 0.000461779796619161 -343.482131276929 186.736139727503 -1.83939826419331 0.0667857810219045 ATXN10 other 0.479739436519234 1 1 3.53874656888084 -1.83939826419331 4.33281891473773e-08 185.521442466119 62.003390723347 2.99211769391609 0.00299225974483199 -426.74012108029 125.283364909449 -3.40619938958956 0.000745285954978698 TUBGCP2 essential 0.000486965517827374 1 1 2.99211769391609 -3.40619938958956 0.0850204773105721 -61.1776153454354 36.8141038992825 -1.66179830189016 0.0975739497622922 -153.086147679368 74.4185337400983 -2.0570970695823 0.0405214111882806 CYP2E1 other 1 1 1 -1.66179830189016 -2.0570970695823 0.000526976089159513 21.9889076068079 6.89874055503806 3.18737999079407 0.00157976332942116 -27.5513792983675 14.5586416866698 -1.89244160899942 0.0593488970417304 PNPLA7 other 1 1 1 3.18737999079407 -1.89244160899942 3.85912029591606e-13 369.079709991477 53.8284741695812 6.85658874202394 3.66065624322141e-11 -345.265106595867 168.816121758947 -2.04521406485615 0.0416538973806253 PAK4 other 5.12684131312449e-09 1 5.01473298758902e-07 6.85658874202394 -2.04521406485615 9.61683851361836e-08 73.2006966080853 14.2555418164204 5.13489403284329 5.00548218788744e-07 -79.3219177297974 62.8820038751582 -1.26144068002791 0.208101573434768 ZNF337 other 0.0010628529925251 1 0.00604962577228076 5.13489403284329 -1.26144068002791 0.298904177849364 16.3703692631924 33.064653036123 0.495101800865954 0.620868044268219 -83.6576632565443 64.8588040060558 -1.28984282918219 0.198036612049472 CEP85 essential 1 1 1 0.495101800865954 -1.28984282918219 0.193512129239706 -11.0876320937761 6.27328286821899 -1.76743697465756 0.078117116132241 1.22835244315657 29.01796785206 0.0423307534634742 0.966261679277143 RBBP8NL other 1 1 1 -1.76743697465756 0.0423307534634742 2.63841894869851e-14 238.919397700453 33.1246990278708 7.21272659713614 3.99049539185151e-12 -365.981317013352 150.96920594971 -2.42421171066679 0.0158953659417401 OSBPL2 other 3.58376445801719e-10 1 5.55476958545731e-08 7.21272659713614 -2.42421171066679 2.51710894624672e-07 376.452707140129 85.1083711116974 4.42321598008341 1.33576607618368e-05 -986.375458937197 394.206009500381 -2.50218270438681 0.0128432447170338 ADRM1 essential 0.00271671568568408 1 0.148603975975435 4.42321598008341 -2.50218270438681 0.00112580938982379 -414.871471931657 249.391946404444 -1.66353195407061 0.0971880417442903 -1762.2880986338 505.733571487427 -3.48461758916001 0.000561774875101896 ASS1 other 1 1 1 -1.66353195407061 -3.48461758916001 2.79699401129582e-12 168.019983133969 23.7313685916159 7.08007978913316 9.2258096239034e-12 -99.4039423876001 48.6415188230596 -2.043602765555 0.0418139467130524 EXOSC2 essential 3.64532229492184e-08 1 1.27722108433319e-07 7.08007978913316 -2.043602765555 7.78626108376011e-06 99.0280852575443 20.052768973109 4.93837461501412 1.27293323755928e-06 28.5022236497218 41.4877674628882 0.687003070850167 0.492579913663693 POMT1 other 0.0750829156306987 1 0.0151008069971658 4.93837461501412 0.687003070850167 7.00792721516048e-11 161.639731693881 25.8946581291115 6.24220373514647 1.37359958737855e-09 -144.620314444101 53.5742249079032 -2.69943829691817 0.00731590902212035 UCK1 other 8.81457085122885e-07 1 1.82139305286396e-05 6.24220373514647 -2.69943829691817 0.420601620724199 -47.1018371522443 41.6868343911838 -1.12989719272629 0.259368415277104 -67.599451571003 85.4443321245667 -0.791151968657813 0.429443140271128 FIBCD1 other 1 1 1 -1.12989719272629 -0.791151968657813 7.44668049470776e-07 1135.32885770809 227.329994859435 4.99418855136166 9.76148762556275e-07 -762.703279995942 469.33353083813 -1.62507732749014 0.105136731705816 PRRC2B other 0.00777656844062331 1 0.0116444785885338 4.99418855136166 -1.62507732749014 1.34395183055436e-05 367.787245140557 113.889228488564 3.22934179133094 0.0013733979886141 -699.459264822499 290.58158695059 -2.40710112489486 0.016662155367566 CHMP2A essential 0.126882492322637 1 1 3.22934179133094 -2.40710112489486 5.95461483045807e-08 181.395324908849 55.8892145955811 3.2456230816883 0.0013000909944463 -529.337699723329 142.554906962079 -3.71321977618167 0.000242600764581954 UBE2M essential 0.000664773199672339 1 1 3.2456230816883 -3.71321977618167 8.73723345328781e-12 1629.15205577104 266.982307147737 6.10209745048588 3.10975673413535e-09 -1469.01038827913 681.189463905353 -2.15653715466633 0.0318079825009529 TRIM28 other 1.125443041118e-07 1 4.08435449461337e-05 6.10209745048588 -2.15653715466633 0.00146694408025887 193.44181949991 54.0361839198865 3.57985715250924 0.000397436175532961 59.5796054174892 145.871887636311 0.408437886030746 0.683227115650643 METTL26 other 1 1 1 3.57985715250924 0.408437886030746 3.12339917897858e-09 333.961538730315 68.9001890895197 4.8470337040209 1.96558143188046e-06 -374.535617074954 147.891244884055 -2.53250702817861 0.0118072633625106 YIPF2 other 3.70653780569388e-05 1 0.0230444767073665 4.8470337040209 -2.53250702817861 2.7264355793851e-06 145.445649526116 46.5837889510261 3.12223743068698 0.0019591918778171 -298.933184962734 102.114472749889 -2.92743209569242 0.00366340283546365 ATG4D other 0.0272752615361685 1 1 3.12223743068698 -2.92743209569242 0.158270933008623 16.1819087116241 13.5288967694229 1.19609965153976 0.232543181800078 -35.9530081896107 30.6390047151315 -1.1734391676194 0.241492397316722 TMEM160 other 1 1 1 1.19609965153976 -1.1734391676194 0.392106118316004 5.1478515833293 42.6403342512272 0.120727280255341 0.903982817972211 -125.040596259436 96.567918614835 -1.29484613578724 0.196306789491505 ZC3H4 other 1 1 1 0.120727280255341 -1.29484613578724 0.558838307972906 2.94484812586304 4.36699105816668 0.674342604928375 0.500580378196985 9.71044261940122 9.88996086691361 0.98184843702335 0.326916259942556 NPAS1 other 1 1 1 0.674342604928375 0.98184843702335 0.0273972826473002 -12.140663133765 16.2491099539571 -0.747158654730402 0.455518155537693 -137.437700843344 50.9602355775468 -2.69695968406981 0.0073693392004338 GMFG other 1 1 1 -0.747158654730402 -2.69695968406981 4.32939838743504e-10 70.0316924208168 11.4876409519668 6.09626403833823 3.12285553573956e-09 -46.2765040935928 35.3390432603479 -1.30950076244756 0.191304189173376 MAP3K10 other 5.30914124251159e-06 1 4.10124617508676e-05 6.09626403833823 -1.30950076244756 0.000192187743574523 34.8776913403588 63.3176302521744 0.550836965967485 0.582129793864284 -530.790428954286 139.065604433592 -3.81683473146485 0.000162271415949243 ARHGEF16 other 1 1 1 0.550836965967485 -3.81683473146485 1.21929245333425e-22 312.516081976293 38.6018200412533 8.0958898218351 1.20146527543902e-14 -395.589181040625 85.5104970502726 -4.62620607629089 5.41576263036223e-06 LRRC47 other 1.79918794414002e-18 0.0802453548940772 1.72542428205798e-10 8.0958898218351 -4.62620607629089 0.0346491450867323 53.5301544736817 29.8111767824646 1.79564043594445 0.0734950559186441 -84.129747246056 59.7815090668215 -1.40728711200681 0.160312825827585 SESN2 other 1 1 1 1.79564043594445 -1.40728711200681 0.272587543225336 -29.745333850131 20.2341395698232 -1.47005676952494 0.142528890124315 -40.6303685676165 40.57630488657 -1.001332395377 0.317422709056323 SMPDL3B other 1 1 1 -1.47005676952494 -1.001332395377 0.0090140426666051 27.7107020351403 90.2153080428568 0.307161862396749 0.758919966574618 -527.238810389624 180.912256335433 -2.91433439098819 0.00381564792043543 ATPIF1 other 1 1 1 0.307161862396749 -2.91433439098819 9.70012671643355e-07 8.42115620706063 15.0984067451351 0.557751314374547 0.577404179288882 -153.263832930208 30.2774206572007 -5.06198446246306 7.01418885196433e-07 MED18 essential 0.0100541813415834 0.0105247903723725 1 0.557751314374547 -5.06198446246306 0.592776994099739 34.9698372087607 39.5063040024311 0.885171065524346 0.376729014768746 -22.8160987992773 79.2235237190356 -0.287996515784808 0.773535842048092 THEMIS2 other 1 1 1 0.885171065524346 -0.287996515784808 0.00129187633385971 381.1422365297 169.628543424834 2.24692276921303 0.0253262569661937 -1115.12512135998 442.878871372152 -2.51790092831712 0.0122934026070662 CLIP1 other 1 1 1 2.24692276921303 -2.51790092831712 9.92646615821214e-07 244.827071956376 64.3580152985735 3.80414266693216 0.00017043785046833 -524.017110602092 165.973739642074 -3.15722903955858 0.00174444978588495 HIP1R other 0.010282826293292 1 1 3.80414266693216 -3.15722903955858 6.54370803019983e-10 124.071662556394 30.544779292118 4.06195970086484 6.13053431241917e-05 -227.493717028095 63.8296512914209 -3.56407582409387 0.000420956312939766 ZNF317 other 7.96631015596527e-06 1 0.648855751626445 4.06195970086484 -3.56407582409387 8.83703950065926e-10 282.169725750449 55.3748665942374 5.0956280909544 5.96385893377258e-07 -279.787744173785 118.854567379483 -2.35403443336316 0.0191769769341956 PPAN other 1.07131429866492e-05 1 0.00718346808572907 5.0956280909544 -2.35403443336316 2.09313801816846e-12 751.152161062625 137.427722117639 5.46579794446156 9.30587202854465e-08 -949.116162393883 294.969784359527 -3.21767249637014 0.00142509431446054 EIF3G essential 2.73698727255707e-08 1 0.00116034918323923 5.46579794446156 -3.21767249637014 0.00978043525411561 6.95639625856257 10.8323666947819 0.642186186506552 0.521213526718262 -60.638493291541 23.2501915830928 -2.60808574737236 0.00953332557895625 ANGPTL6 other 1 1 1 0.642186186506552 -2.60808574737236 0.00744540450020147 21.9102045074089 43.1550759110019 0.507708630905759 0.612008542042195 -255.988433789316 92.6264602173264 -2.76366421850407 0.00604768451185234 C19orf66 other 1 1 1 0.507708630905759 -2.76366421850407 6.90468839252916e-06 606.555090522212 174.163667741389 3.48267292707035 0.000565719224564031 -829.143564267166 374.902810167908 -2.21162269734872 0.0277012959966589 DNMT1 other 0.0668788117700375 1 1 3.48267292707035 -2.21162269734872 0.00560061183170521 92.8466089181209 28.9957730212496 3.20207393160645 0.00150154119306607 37.5467615830635 63.7652736807802 0.588827733587862 0.556392249355676 ZNF426 other 1 1 1 3.20207393160645 0.588827733587862 0.0329792499392124 33.5570021326293 13.8253075101746 2.42721560500071 0.0157685115846605 -22.6906164314004 43.5748491815268 -0.520727365845248 0.602917953631649 ZNF331 other 1 1 1 2.42721560500071 -0.520727365845248 2.3129596566876e-16 86.2212276693057 16.4363472469354 5.24576576376371 2.86786806999659e-07 -56.8369592303661 24.9153212965724 -2.28120514898538 0.0232056465446098 ZNF236 essential 3.23883740725964e-12 1 0.00350568192876383 5.24576576376371 -2.28120514898538 3.98192594589637e-05 185.211477640483 40.4960214854009 4.57357218923969 6.86375884589427e-06 140.26655971119 120.59423886986 1.16312819771233 0.245644094488675 LRP3 other 0.359328997357689 1 0.0779517092128212 4.57357218923969 1.16312819771233 0.654786514875126 9.71181288959879 20.0750604491844 0.483775025942368 0.628877460208082 -36.1796427517668 51.7508280702414 -0.699112344688671 0.484991237016622 C12orf65 other 1 1 1 0.483775025942368 -0.699112344688671 1.93901589336883e-11 208.544820867041 30.205578105323 6.90418240431858 2.7499516083231e-11 -103.566087026635 70.9677992543966 -1.45933913852089 0.145458877523446 NOL11 essential 2.47689890218934e-07 1 3.77430858242345e-07 6.90418240431858 -1.45933913852089 1.51238884250771e-08 384.434943427421 69.9209223643523 5.49813890360545 7.87398434800177e-08 -180.593140286824 158.22767772565 -1.14134987558847 0.25458041523653 UBE4B other 0.000174015460218937 1 0.000984405523187181 5.49813890360545 -1.14134987558847 0.00528075369546188 138.272635527901 56.907024672748 2.42979906827071 0.0156586461440238 -163.932944502454 120.413677947763 -1.36141464405372 0.174343497343826 CASZ1 other 1 1 1 2.42979906827071 -1.36141464405372 0.345146896764373 -8.79247419119619 6.71243690462121 -1.30987811373586 0.191179573183314 6.1869429108712 12.8669051832747 0.480841571671285 0.630958718373021 HSD17B3 other 1 1 1 -1.30987811373586 0.480841571671285 0.0151118348347356 23.2398155095928 7.98077118525622 2.91197616998798 0.00384542662631741 7.83897910339554 15.1804098301173 0.516387844012178 0.605942450502354 HABP4 other 1 1 1 2.91197616998798 0.516387844012178 0.391949508353323 -20.5026540007474 22.4790969448385 -0.912076408187521 0.362415091035077 37.9917672632513 42.8826291368716 0.885947714212909 0.376310980409002 FBP2 other 1 1 1 -0.912076408187521 0.885947714212909 0.000265598062063267 51.0441723912958 12.885262193448 3.96143839566191 9.1944769967662e-05 -14.863190039419 24.6994421341359 -0.601762175789281 0.547759883989643 SLC35D2 other 1 1 0.956869221053459 3.96143839566191 -0.601762175789281 6.34968475527748e-11 2.6629589206856 1.90907703164172 1.39489338384401 0.164015434604171 -17.7107280943441 3.53082170331576 -5.01603580767393 8.76084891302222e-07 POLN other 7.9999678231741e-07 0.0131360168601855 1 1.39489338384401 -5.01603580767393 3.62997527479543e-08 66.549928957761 18.9777096299926 3.50674187008239 0.000518463704625818 -163.435734499224 41.5963219122262 -3.92909101059692 0.000104507008937835 PPIL4 essential 0.000409969407535396 1 1 3.50674187008239 -3.92909101059692 0.00161149083015649 -14.4259743236661 28.7242280147622 -0.50222322132564 0.615855915314274 -227.000408556081 62.9592431582956 -3.60551361752148 0.000361226759125675 ULBP2 other 1 1 1 -0.50222322132564 -3.60551361752148 0.0205715834551872 90.6233531005224 53.4423693940433 1.69572109410672 0.0909113446406714 -208.418564912099 117.773852545867 -1.76965056680073 0.077737668921468 AKAP12 other 1 1 1 1.69572109410672 -1.76965056680073 0.335793561727487 -132.896109541404 124.272082187543 -1.06939633747221 0.285699631087816 -340.395361139703 274.736706416554 -1.23898755859582 0.216260948965653 SYNE1 other 1 1 1 -1.06939633747221 -1.23898755859582 0.00037546047467815 9.75020200266642 4.97996968291559 1.95788380722793 0.0511123622390951 -32.2727691641286 10.9153541751057 -2.95663966980861 0.00334136661134448 ULBP3 other 1 1 1 1.95788380722793 -2.95663966980861 2.25455309107173e-06 51.1427407977974 35.6367469093694 1.43511249575789 0.152231689762173 -353.7126145061 78.1104582822746 -4.52836434818828 8.39835224296144e-06 LATS1 other 0.0226875677554549 0.123808508765737 1 1.43511249575789 -4.52836434818828 0.819269493268031 82.9608941734224 131.821765676214 0.62934139705877 0.529574608797391 73.2830292121162 344.016944360474 0.21302156888914 0.831445782223925 EPS8L1 other 1 1 1 0.62934139705877 0.21302156888914 0.325023869144469 -16.1315412720902 15.8424380526038 -1.01824865708967 0.309333854972018 -52.278736360699 39.081981889703 -1.33766850688995 0.181960396098649 LILRB2 other 1 1 1 -1.01824865708967 -1.33766850688995 1.37756031817789e-26 292.080752223 24.776546813837 11.7885980809836 8.09874984429674e-27 -12.7678295651841 135.391847509268 -0.0943027944449179 0.924928586350626 AAR2 other 2.06482516091685e-22 1 1.22436900146078e-22 11.7885980809836 -0.0943027944449179 0.73588188343404 36.9205314704744 49.1092345442612 0.751804254598973 0.452728361450635 -41.7753495341198 328.516240157042 -0.127163727169621 0.898891693025017 BPIFA2 other 1 1 1 0.751804254598973 -0.127163727169621 1.11118813745068e-06 388.026467832606 75.2141516593179 5.15895558578085 4.4167390869149e-07 -241.657704743357 431.062776789562 -0.560609075418568 0.575465124889828 RBM39 essential 0.0114674615784911 1 0.00535176275161479 5.15895558578085 -0.560609075418568 0.713055261325713 -1.44901182510996 2.49461671726315 -0.580855493784904 0.561764005371359 -10.0358474118727 15.4262108157461 -0.650571130638817 0.515809951567193 COX4I2 other 1 1 1 -0.580855493784904 -0.650571130638817 0.000113879243914297 10.2001091404685 2.90850499780948 3.50699385015692 0.000519948529502019 -38.2882039628777 18.2816536829784 -2.0943512346767 0.0370377717799455 ZNF341 other 0.975375724125954 1 1 3.50699385015692 -2.0943512346767 0.0253138431938093 42.6261056573842 15.777487228941 2.7017043359854 0.00727696839497795 3.07055191898061 92.7483407721713 0.0331062733135374 0.973611077070301 GGT7 other 1 1 1 2.7017043359854 0.0331062733135374 0.00116148930871815 113.990888982472 30.6742179148573 3.71617914754592 0.000239770733872904 88.9139580428727 180.31913287614 0.493092200614933 0.622295422388254 ACSS2 other 1 1 1 3.71617914754592 0.493092200614933 0.502910484027374 11.4813815269739 12.4381499201222 0.923077917592842 0.356664253748866 24.1803115765617 30.2055099423725 0.800526513960334 0.424001590734817 C1QL1 other 1 1 1 0.923077917592842 0.800526513960334 0.53356062837352 13.4874452702687 12.8807353571688 1.04710211771894 0.295845205987392 15.3345141059332 31.28030956329 0.490228975352901 0.624308878241542 GFAP other 1 1 1 1.04710211771894 0.490228975352901 0.664642145017993 0.372418403469537 1.0801933467429 0.34477013267346 0.730494383229847 2.26216721674701 2.62320289466383 0.862368374687582 0.389132660492705 HIGD1B other 1 1 1 0.34477013267346 0.862368374687582 6.56596371325329e-07 305.273066121057 72.2026945247261 4.22800102032916 3.10619615542155e-05 -455.959047984621 219.241075790274 -2.0797154289682 0.0383731189584725 ATP6V1E1 essential 0.00688375635697475 1 0.336866973055467 4.22800102032916 -2.0797154289682 3.65619356299155e-26 77.9798004545952 6.70419866427638 11.6314871261369 2.70198836510479e-26 -15.3102647727344 28.2342280014626 -0.542259018803039 0.588019867727367 ZNF227 other 5.47149366701686e-22 1 4.08135342549078e-22 11.6314871261369 -0.542259018803039 0.00231409413648428 57.4524480039742 25.7029702638957 2.23524547607154 0.02609519939648 -248.495033831717 107.702204911984 -2.30724184370033 0.0216833496315467 ZNF428 other 1 1 1 2.23524547607154 -2.30724184370033 0.781035074942188 1.0386782112177 3.16623292259785 0.32804857905573 0.74309014233967 -4.10546015345532 7.9234997968425 -0.51813721950133 0.604721704780743 TEX101 other 1 1 1 0.32804857905573 -0.51813721950133 0.0019079621082993 11.0655059899812 5.60684803928708 1.97356980471834 0.0493015911711625 -14.7513121322209 10.3748070235119 -1.42183966398515 0.156059018558698 ZNF141 other 1 1 1 1.97356980471834 -1.42183966398515 0.0573864441108747 111.043685138383 361.440954701799 0.307224966329557 0.758871981686825 -1835.27621328543 922.80696128871 -1.98879753867748 0.0475749032948178 COX4I1 other 1 1 1 0.307224966329557 -1.98879753867748 8.71721926150832e-13 74.6967977275448 19.1206653843883 3.90660033141595 0.000114232636442301 -207.890954125791 48.8176087730375 -4.25852390870509 2.7082195296071e-05 EMC8 other 1.15006273717079e-08 0.39407302375313 1 3.90660033141595 -4.25852390870509 5.88887609141565e-05 177.007919238134 51.4269711140583 3.44192775509865 0.00065431468053612 -132.292361705046 131.314140156006 -1.00744947610271 0.314479997524077 GSE1 other 0.520988867807543 1 1 3.44192775509865 -1.00744947610271 0.271717200538236 -34.5694489829577 35.6093675317948 -0.970796489212886 0.332382835437822 -144.768151008029 90.9154643876465 -1.5923380250335 0.112296065841025 GINS2 essential 1 1 1 -0.970796489212886 -1.5923380250335 1.27915531502061e-24 437.987079805272 82.9624889381435 5.27933871573975 2.40235850543062e-07 -1436.0493720282 211.841758931524 -6.77887768337679 5.86838528583383e-11 CHMP1A essential 1.90363893981367e-20 8.97980316438293e-07 0.00294529152765794 5.27933871573975 -6.77887768337679 1.15862798267432e-05 98.4782955843066 36.6395528317132 2.68775921028897 0.00756956565482919 -160.566674101658 55.6753708949641 -2.88398032236874 0.00419297411992226 F12 other 0.109942209275966 1 1 2.68775921028897 -2.88398032236874 3.62530488900965e-05 47.6835965681927 10.5481457201719 4.52056672643463 8.69438284729242e-06 12.2420957988684 16.0283595141583 0.763777215506962 0.445562780002943 PRR7 other 0.328307610748714 1 0.0980726385174585 4.52056672643463 0.763777215506962 0.000153215099730073 100.867326194051 37.2736539129231 2.70612927913351 0.00718417297151334 -44.4900412036703 55.0725960501221 -0.807843544603917 0.419800104017323 NFATC1 other 1 1 1 2.70612927913351 -0.807843544603917 0.049357495338131 -103.557907966354 173.503847948859 -0.596862312799414 0.551073149046982 -983.680068486061 419.700649278966 -2.34376589642164 0.0197772807674231 IDO1 other 1 1 1 -0.596862312799414 -2.34376589642164 0.0136056364195204 0.743908223818245 0.995321175694798 0.74740520144058 0.455371304704747 -6.74675354650568 2.49163001225938 -2.70776700927109 0.00714008173896582 GJA9 other 1 1 1 0.74740520144058 -2.70776700927109 6.6590840533704e-06 1565.4058339173 356.639405162915 4.3893238135091 1.5522483407564e-05 -1415.96325332867 909.76941417187 -1.556397952351 0.120614416578367 CAP1 essential 0.0645664789814794 1 0.171895981255363 4.3893238135091 -1.556397952351 4.85564129727461e-05 844.970650354275 215.220713008405 3.92606565856547 0.000106031656938956 1589.98025594358 549.017352420341 2.89604736341056 0.00404242307847834 PPT1 other 0.433997219150405 1 1 3.92606565856547 2.89604736341056 0.0148002346687028 100.627558477661 40.7180914468514 2.47132306309121 0.0139916870809417 -92.8600053537194 121.001937369407 -0.767425773276893 0.44340507762672 TRAF3 other 1 1 1 2.47132306309121 -0.767425773276893 0.000326138799632419 31.9182131578617 15.4781712016902 2.06214369526913 0.0400035575401676 -98.9221197518902 36.1165621895121 -2.7389683224229 0.00650969618166419 HAUS8 essential 1 1 1 2.06214369526913 -2.7389683224229 1.21116754528848e-20 282.387482631446 50.600702226516 5.58070284019631 5.12220308326773e-08 -409.404369156874 81.4426158409807 -5.02690593774946 8.32579711698426e-07 MRPS25 essential 1.76600339778513e-16 0.0124853653566296 0.000645090256306738 5.58070284019631 -5.02690593774946 2.09479820116097e-05 192.579432198303 87.2223979244256 2.20791260938693 0.0279615359302283 -371.418389227205 140.38580364139 -2.64569763888646 0.00855617089377524 SH3BP5 other 0.194208741229633 1 1 2.20791260938693 -2.64569763888646 4.02963119877948e-24 87.000229951913 16.0658785001152 5.41521772066738 1.20423247243118e-07 -159.951182561529 25.8823052524205 -6.17994344018372 1.94967732200675e-09 HACL1 other 5.98400233018752e-20 2.97286798059589e-05 0.00149433207503985 5.41521772066738 -6.17994344018372 5.21453532153097e-10 232.851787916154 56.1410642220615 4.14761977071057 4.31540007910314e-05 -245.628483353884 89.7361008363105 -2.73723151624272 0.00654446527385721 TBC1D5 other 6.37737669823238e-06 1 0.463085582488558 4.14761977071057 -2.73723151624272 4.66642177006228e-19 166.810649283817 23.8753620916673 6.98672751614666 1.64683598270818e-11 -108.365557938072 38.4277659663984 -2.81998068877666 0.00510316734746007 CAPN7 other 6.71824742235867e-15 1 2.26851656618052e-07 6.98672751614666 -2.81998068877666 0.00024655838726696 64.0155776629988 58.6889282248651 1.09076072096128 0.276203968983167 -279.504624002044 93.3909610896209 -2.99284449737938 0.00298037371163864 RFTN1 other 1 1 1 1.09076072096128 -2.99284449737938 7.15998628822778e-29 170.469402178576 22.922368306793 7.4368145514902 9.60174781224237e-13 -204.07482974526 36.8939076738214 -5.53139644489501 6.62570414930458e-08 RBSN other 1.07915313336169e-24 0.00100273406595576 1.34808539283883e-08 7.4368145514902 -5.53139644489501 0.00319750859833124 12.6997076016193 21.3599739877471 0.594556323378685 0.552562858603975 110.687826301363 33.9954090249385 3.25596395149015 0.00125193398717484 GALNT15 other 1 1 1 0.594556323378685 3.25596395149015 0.139356223618462 66.7391217085522 124.543108665598 0.53587165459109 0.592420684884633 -288.858716871086 200.454067006576 -1.4410219816673 0.150559313914677 SLC6A6 other 1 1 1 0.53587165459109 -1.4410219816673 0.857466696446107 3.88648709399465 9.7732723507738 0.397664871550105 0.691142374486122 -6.75004027273066 23.235887696951 -0.290500641110277 0.77162143287484 KCNC3 other 1 1 1 0.397664871550105 -0.290500641110277 0.54298162892246 0.595905293522646 1.77251678847386 0.336191621652125 0.73694671021824 -4.02438841643875 4.21414645573424 -0.954971180691339 0.340313114466493 NAPSA other 1 1 1 0.336191621652125 -0.954971180691339 0.0889283171920949 -20.6278612370283 17.8907189595274 -1.15299230196914 0.249774065499514 -88.8905321619897 42.5350610973586 -2.08981790242473 0.0374233767371842 NAPSB other 1 1 1 -1.15299230196914 -2.08981790242473 1.23088731438715e-08 199.590173453714 61.973532509089 3.2205711918139 0.00141079030791457 -659.969415202486 147.341646674823 -4.4791776805577 1.04411120588492e-05 NR1H2 other 0.000142192102558004 0.153640963945965 1 3.2205711918139 -4.4791776805577 0.0815491116282143 26.9637920053946 13.4595935788752 2.00331398176199 0.0459865008991095 -17.8288783576218 32.0000910258666 -0.55715086382755 0.577813836973308 LRRC4B other 1 1 1 2.00331398176199 -0.55715086382755 0.000384461547052555 416.420965255355 125.894257385253 3.30770421069366 0.00104771944837199 -161.265083059094 189.301617972662 -0.851894900773552 0.394909512729046 PDLIM4 other 1 1 1 3.30770421069366 -0.851894900773552 0.000158736297093442 39.8925465588668 15.0396544575981 2.65249089806801 0.00838959840625953 -46.7957121596079 22.5082066433413 -2.07905111682684 0.0384113332918002 KIF3A other 1 1 1 2.65249089806801 -2.07905111682684 7.32481937762452e-13 691.770342237508 131.7906419642 5.24900958009918 2.80639259650854e-07 -788.255592329976 211.087201819767 -3.73426520193779 0.000223157622876548 MGAT1 other 9.67681887977975e-09 1 0.00343165686701065 5.24900958009918 -3.73426520193779 2.65555975276795e-07 236.70822436803 46.6128815666459 5.07817187893846 6.50386029118713e-07 -47.4804672384162 74.5804706902284 -0.636634051769763 0.524821233476996 GFPT2 other 0.0028632245254344 1 0.00781698968397781 5.07817187893846 -0.636634051769763 1.37261066513544e-09 177.899760494414 40.5980660718356 4.38197622959756 1.59647157294351e-05 -474.646083048031 104.721185736785 -4.53247430029149 8.24624104862643e-06 TUBG1 essential 1.64974075842629e-05 0.121599070503045 0.176617650114741 4.38197622959756 -4.53247430029149 2.3869503260489e-12 610.589035198906 86.3703811817784 7.06942619500355 9.80760674112361e-12 -489.608482198251 211.611652447591 -2.3137122957797 0.0213168166341882 PSME3 other 3.11687973575466e-08 1 1.35707854476927e-07 7.06942619500355 -2.3137122957797 0.0876088414662921 1065.39239202801 493.022153926306 2.16094222854589 0.0314414082786689 -373.406911886563 1207.39151019193 -0.309267465221124 0.757319349007339 RPL27 essential 1 1 1 2.16094222854589 -0.309267465221124 0.114563009012899 11.9219208647088 18.8349251115227 0.632968848780569 0.527206051820975 -93.6644803217143 48.5839814993195 -1.92788811108505 0.0547537429790525 PSMC3IP other 1 1 1 0.632968848780569 -1.92788811108505 0.596033849764208 -21.4488436207688 23.313218827972 -0.920029266616492 0.358250484830248 20.6154228194571 57.1061764864381 0.361001630434022 0.718336434657226 AOC3 other 1 1 1 -0.920029266616492 0.361001630434022 4.73149924309712e-08 817.973987229979 153.687067310768 5.3223345434523 1.93120939541289e-07 -883.047353587993 396.526030922365 -2.22695935380062 0.0266454805600727 ACLY other 0.000530732270098204 1 0.0023765462819951 5.3223345434523 -2.22695935380062 4.39928769767421e-07 170.879154728822 31.4672707559133 5.43037736110973 1.11422212563892e-07 -50.080848906342 77.0963502946699 -0.649587804285521 0.516424510797013 VPS25 essential 0.00466896403354164 1 0.00138475525774406 5.43037736110973 -0.649587804285521 0.181943856197004 4.23852412361471 13.2919563092099 0.318878878700336 0.750026401863623 60.0115787835877 32.5659421710008 1.84277115240432 0.0662872600346562 RAMP2 other 1 1 1 0.318878878700336 1.84277115240432 0.0921299450641914 4.05849265075169 1.96837777672466 2.06184640913033 0.0400295145921337 4.3580678261863 4.82262169362401 0.903671924328649 0.366849162081605 AOC2 other 1 1 1 2.06184640913033 0.903671924328649 0.00119464625592469 101.406922227906 63.6841997679538 1.59234037009811 0.112295539065944 -245.440249818289 93.5095245614241 -2.62476203327358 0.00908704592028076 NDUFA2 other 1 1 1 1.59234037009811 -2.62476203327358 9.37421195641273e-08 285.425083048433 108.386817858787 2.63339295946765 0.00886416462257254 -641.418002530483 159.147792445073 -4.03032924727409 6.9658993425343e-05 ANKHD1 other 0.00103669410025968 0.999815532633948 1 2.63339295946765 -4.03032924727409 3.15814539411892e-09 1134.00481026759 265.03182555429 4.27874957241802 2.48776183816274e-05 -1176.76172457726 377.896369091103 -3.11397997130152 0.00201317216108437 DIAPH1 other 3.74619206650386e-05 1 0.271613837490608 4.27874957241802 -3.11397997130152 1.54345313682707e-09 292.637854130097 65.3890684401552 4.47533297401114 1.0630051202676e-05 -281.317281571617 93.4764062698973 -3.00950039477728 0.00282536606251521 NDFIP1 other 1.85121769231039e-05 1 0.119014053265161 4.47533297401114 -3.00950039477728 2.53769936555414e-19 318.49011871753 57.8590619013312 5.50458490427412 7.59922673421982e-08 -503.74067784747 84.9562904091952 -5.92940999920293 7.8753493920294e-09 UBE2D2 other 3.66215395443117e-15 0.000119760438204591 0.000951347194856979 5.50458490427412 -5.92940999920293 8.83653369552833e-21 257.756628707102 47.422738885708 5.43529612088228 1.09312281911155e-07 -536.883455536234 104.85826422678 -5.12008719098288 5.3090102030189e-07 EXOC4 essential 1.28951536218845e-16 0.00798103503819831 0.00135929822556521 5.43529612088228 -5.12008719098288 2.89125732909896e-18 438.620948448479 50.9467929969039 8.60939271437822 3.56725306021722e-16 -189.026672136264 115.565902589619 -1.63566127984574 0.102909277979923 ACAP3 other 4.13334147767988e-14 1 5.18214852057756e-12 8.60939271437822 -1.63566127984574 8.41819714838662e-07 47.770078496578 14.1856868466209 3.36748435328368 0.000852644290397948 -100.098294729515 32.1783101123373 -3.11073808351226 0.00203692944086196 C1orf159 other 0.00876250141175563 1 1 3.36748435328368 -3.11073808351226 2.75838765722257e-18 911.130388048162 96.2331212921341 9.4679500759645 2.20038485420191e-18 -1475.10833643063 1447.38628059262 -1.01915318405993 0.309111566956979 ANO1 other 3.944770188594e-14 1 3.24094685175399e-14 9.4679500759645 -1.01915318405993 2.30857237829348e-61 560.085111355928 24.9873304087149 22.4147638901267 1.17288912217387e-61 -124.770311373963 375.622726893061 -0.332169228432988 0.740040923157111 PPFIA1 other 3.54319688620484e-57 1 1.80038480253689e-57 22.4147638901267 -0.332169228432988 0.650162788597498 19.2618870726776 20.7439067090262 0.928556387321984 0.353818904689219 15.921369920716 58.0794045694631 0.274131080350075 0.784160761326066 TMEM204 other 1 1 1 0.928556387321984 0.274131080350075 0.380631148583847 -110.963987100588 121.109765008102 -0.916226590755623 0.360240174040981 -437.379386979283 346.731382056102 -1.26143582500564 0.208073518262736 KREMEN2 other 1 1 1 -0.916226590755623 -1.26143582500564 2.83240301640835e-08 188.986541909406 36.4781277700456 5.1808180260993 3.92436034848867e-07 -165.355001619533 104.816837054154 -1.57756145164065 0.115657498762289 THOC6 other 0.000321676010573497 1 0.00476652807927434 5.1808180260993 -1.57756145164065 5.50201219859212e-13 731.849987115986 132.493530172624 5.52366584362623 6.88260865047088e-08 -1413.93106298399 373.708768889084 -3.78351053197695 0.000184547290948963 TRAF7 other 7.28796535825512e-09 1 0.000862459689990505 5.52366584362623 -3.78351053197695 0.00412762333733181 46.1591168940542 34.1877017071024 1.35016729961888 0.177916497921916 209.642972834523 65.2453681902107 3.21314721105333 0.00144658547466692 BARX1 other 1 1 1 1.35016729961888 3.21314721105333 0.00169157161648134 90.7827585235073 89.1611814520872 1.01818702988241 0.309358255998726 -559.91156285902 170.159262589654 -3.2905147468185 0.0011116190160601 NINJ1 other 1 1 1 1.01818702988241 -3.2905147468185 0.587579051366707 17.0638336515026 24.8258362214513 0.687341747496031 0.492365245140561 -30.103249609844 56.012521761391 -0.537437856093706 0.591338724035452 CA6 other 1 1 1 0.687341747496031 -0.537437856093706 1.01441916814409e-09 77.9213932282984 13.4773007872792 5.78167649874269 1.75766156434182e-08 -37.6049092633562 29.3290817966801 -1.28217137938539 0.200710622890209 NPHP4 other 1.22531691320124e-05 1 0.000225455248858126 5.78167649874269 -1.28217137938539 0.557069474781502 -150.019516810157 171.888275756526 -0.872773411391101 0.383443065041633 58.5567721873298 235.343259143149 0.248814316588147 0.803664530436517 MAP1B other 1 1 1 -0.872773411391101 0.248814316588147 0.21734268973296 84.7001064809169 94.0171304461426 0.900900783495377 0.368318589155464 226.143006089377 130.128071338117 1.73784951827789 0.0831993380443965 CKMT2 other 1 1 1 0.900900783495377 1.73784951827789 5.4888765123201e-12 102.275883551287 17.3433057552621 5.89713893040576 9.397214713071e-09 -44.6250041594108 24.0046778480689 -1.8590128324926 0.0639431318246498 ZCCHC9 essential 7.1075461958033e-08 1 0.000121477794595869 5.89713893040576 -1.8590128324926 0.0527139186043215 36.034649971712 15.9009564140013 2.26619387120528 0.0241091280944476 -33.4951901684951 46.3848404173601 -0.72211502437247 0.470752763796258 KRT34 other 1 1 1 2.26619387120528 -0.72211502437247 0.20207684874848 14.1151326564036 8.30956646434506 1.69866053986923 0.0903581850863347 -10.7285105984746 24.2399201878638 -0.442596779004496 0.658357366534585 KRT33B other 1 1 1 1.69866053986923 -0.442596779004496 7.67467045681846e-05 1613.42347591179 456.625949226963 3.53335915018235 0.000471327985744216 -3105.07035060894 1302.33270777179 -2.38423740114883 0.0177024968856006 TNS4 other 0.66961499735741 1 1 3.53335915018235 -2.38423740114883 9.79129603625984e-06 869.833202486242 201.158372301375 4.32412130071852 2.05368097144083e-05 -1132.50896557295 581.692143767163 -1.946921542104 0.0524270860751592 TOP2A essential 0.0935362510343902 1 0.22557631790306 4.32412130071852 -1.946921542104 2.51470475968761e-10 203.19955346448 29.8853810516451 6.7992960542591 5.30770155965538e-11 -55.5045219017648 74.8503481680406 -0.741539929475759 0.458920378244281 STARD3 other 3.1096839058297e-06 1 7.24288954830573e-07 6.7992960542591 -0.741539929475759 1.9068030898985e-18 231.28248898437 24.0303354315703 9.62460510145514 2.1348536572126e-19 3.51282635859451 69.4921893729744 0.0505499451131217 0.959716086819737 RARA og 2.73016066411668e-14 1 3.15958341267465e-15 9.62460510145514 0.0505499451131217 0.952182660374617 14.9941975919673 54.2164252022453 0.276561900494803 0.782298475699835 -17.8467490584692 135.78941141161 -0.131429607602992 0.895519637841762 PPP1R1B other 1 1 1 0.276561900494803 -0.131429607602992 0.819466434644614 -4.15866832205837 13.289241480312 -0.312934965341658 0.75453520324263 -42.9421378667605 74.401425922825 -0.577168210610688 0.564234205983718 KHDRBS3 other 1 1 1 -0.312934965341658 -0.577168210610688 5.57024643129569e-10 144.724049780619 22.0808699619385 6.55427299875795 2.34132725879639e-10 133.119412813627 89.9286196640295 1.48027861776325 0.139817755457388 CHD1L other 6.80461304047081e-06 1 3.15751394121281e-06 6.55427299875795 1.48027861776325 1.07853558220719e-08 107.146929527297 17.6746855864925 6.06216891400784 3.94812927655934e-09 -116.644870171985 68.1930684990182 -1.71050918721548 0.088185292606882 PEX11B other 0.000124905205775415 1 5.16770641008852e-05 6.06216891400784 -1.71050918721548 0.0702315774825968 8.48591596190986 4.09135583941958 2.07410850949442 0.038897102508496 16.2012053006593 16.6628390922813 0.97229561006588 0.331663995564362 FMO5 other 1 1 1 2.07410850949442 0.97229561006588 9.51982960218945e-06 258.111431455272 52.6877315680361 4.89889057231417 1.56451454867442e-06 -6.1511900466962 203.281584291536 -0.0302594554648614 0.975879857655409 PIAS3 other 0.0910190908265334 1 0.0184597071598095 4.89889057231417 -0.0302594554648614 1.45713362073945e-07 176.517848321789 31.1210739853587 5.67197161655906 3.25305105555292e-08 103.863143069387 125.781993460348 0.8257393623049 0.409591093508132 PRKAB2 other 0.00159381275436481 1 0.000412649526396888 5.67197161655906 0.8257393623049 0.102279735013497 -8.0172902373546 10.6378837333751 -0.753654621379375 0.451639944835141 -78.9378610693436 36.9599673372759 -2.13576652676668 0.0334972415099027 CLUHP3 other 1 1 1 -0.753654621379375 -2.13576652676668 3.28275424328808e-09 333.766444567727 81.3218808047545 4.10426371432636 5.15649641574409e-05 -331.016277157261 111.343001051164 -2.97294193646849 0.00317419215427377 MCCC2 other 3.89170515541802e-05 1 0.549476258061691 4.10426371432636 -2.97294193646849 0.000146791469530835 39.2447786067697 12.0072719624532 3.26841756641212 0.00119946340104762 -45.3396236886261 29.8454858420783 -1.51914510383688 0.129716438257594 ZNF304 other 1 1 1 3.26841756641212 -1.51914510383688 0.000341581615700781 21.2369887495915 6.4603305301829 3.28729136231831 0.00112472691054943 -21.5957787243913 16.5949688774152 -1.30134493676465 0.19408244207601 ZSCAN5A other 1 1 1 3.28729136231831 -1.30134493676465 0.236849383386555 1.26292619666325 3.56388194672507 0.354368134394512 0.723302395360902 -13.3991831673209 9.09482279566984 -1.47327589204932 0.141684795607502 ZNF132 other 1 1 1 0.354368134394512 -1.47327589204932 7.14659911761223e-09 222.410351481868 40.5679928425817 5.48240955240008 8.54136463656038e-08 -127.078738101215 89.8127130806016 -1.41493040063459 0.15806430334144 SELENOS other 8.35080106892989e-05 1 0.00106656020216729 5.48240955240008 -1.41493040063459 4.94328224806461e-05 224.684111575238 57.0025618685204 3.94164936118984 9.94857236763015e-05 -125.18311517655 126.196895020722 -0.991966681557378 0.32196560326394 CHSY1 other 0.441583403219612 1 1 3.94164936118984 -0.991966681557378 5.7758018748864e-06 106.578572728776 25.0339306116966 4.25736470959855 2.72379463105242e-05 -71.9551198236343 55.422146124716 -1.29830987890137 0.195118709033066 SNRPA1 essential 0.0563198440820173 1 0.296539521482677 4.25736470959855 -1.29830987890137 2.95309561014494e-14 365.75317220518 48.0569109197915 7.61083401335622 3.09906264502131e-13 -261.651919327333 89.5986979261644 -2.92026475142477 0.00374644390682071 LLGL1 other 4.00676012384466e-10 1 4.3774259860926e-09 7.61083401335622 -2.92026475142477 5.2061886377693e-09 13.1645172691344 5.35972475886093 2.45619278254358 0.0146741964835186 -43.6040972272385 11.9919928580943 -3.63610100032764 0.00033163018004135 THAP1 essential 6.12351907574426e-05 1 1 2.45619278254358 -3.63610100032764 0.00929119115104414 36.5762886985272 18.7828391279213 1.94732481332683 0.0523729912289687 -103.613808423505 56.8412540110121 -1.82286281726703 0.0692600871756012 RHPN2 other 1 1 1 1.94732481332683 -1.82286281726703 1.84407158188459e-11 87.6026940938215 14.7705231837038 5.93091341479853 8.18371322940133e-09 -103.133067610154 39.1187477301819 -2.63641025325006 0.00880914556964673 C19orf12 other 2.35635466733213e-07 1 0.000106020004886894 5.93091341479853 -2.63641025325006 4.53952980063724e-05 21.4023707544334 5.66891600481667 3.77539034557023 0.000190499031456823 -25.7055107829876 17.1554626221482 -1.49838633612835 0.135021789970775 FAAP24 other 0.407059637223141 1 1 3.77539034557023 -1.49838633612835 1.02125219495904e-16 216.360205096005 25.2129144630391 8.58132467839759 4.21330339502687e-16 -85.8312655842345 78.1899657226692 -1.09772737193246 0.273154041927814 ACTR10 essential 1.43485933391745e-12 1 6.11813785991852e-12 8.58132467839759 -1.09772737193246 0.00160019482542745 10.5915621870319 4.19003691629899 2.52779686637876 0.011963592296793 39.491320515635 12.7356054040398 3.10085930450609 0.00210288314092459 ABHD12B other 1 1 1 2.52779686637876 3.10085930450609 0.000990372445571334 -83.1630420456044 22.1940648082527 -3.74708476180898 0.000212520806654555 -76.7177902991964 66.5341379808034 -1.15305905550818 0.249754844846518 GCH1 other 1 1 1 -3.74708476180898 -1.15305905550818 7.85702365225648e-05 511.466521681824 176.040229132862 2.90539568257326 0.00392586959923935 -1362.75962172137 527.7395103822 -2.58225809307783 0.010263891984397 LGALS3 other 0.684661041057629 1 1 2.90539568257326 -2.58225809307783 0.172310972469682 43.1850088870594 22.9906279102997 1.87837448614062 0.0612534314951717 22.0784774265308 55.229329026651 0.39976001547795 0.689604212876818 PODNL1 other 1 1 1 1.87837448614062 0.39976001547795 2.91067293847516e-05 1503.79546662969 502.079334242278 2.99513515906638 0.00295939242662294 -3308.95476989598 1239.51372062866 -2.66955880747954 0.00798635486182571 DNAJB1 other 0.266413894058631 1 1 2.99513515906638 -2.66955880747954 7.39058757606998e-05 116.667012934519 30.2002059942505 3.86311977331314 0.000135834982531697 -73.824567502021 71.5039826122251 -1.03245392501255 0.302649043564961 ZSWIM4 other 0.64630688352732 1 1 3.86311977331314 -1.03245392501255 6.07793117560688e-06 33.8209374719388 11.5559970517139 2.92670007794114 0.00367498625175448 -129.586337014976 38.3276153409052 -3.38101746905904 0.000813143737089753 FBXW9 other 0.0591321924074794 1 1 2.92670007794114 -3.38101746905904 0.000125197705366513 51.6092745540215 15.0934980668503 3.41930507596317 0.000710436292222098 -61.8536469115249 37.4389565291977 -1.65211994792875 0.0995065072809301 RFX1 other 1 1 1 3.41930507596317 -1.65211994792875 0.000205967167057403 11.1758390248707 4.66907708429555 2.39358631761738 0.0172750707683329 -25.3497815642745 9.97238547445626 -2.54199776264231 0.0115054746141757 ZNF20 other 1 1 1 2.39358631761738 -2.54199776264231 0.0958937486589591 -4.52838196353733 20.6694176446199 -0.219086093347968 0.826724870703532 -106.512169313064 49.6531922632947 -2.14512228636308 0.0327074589508363 C19orf57 other 1 1 1 -0.219086093347968 -2.14512228636308 9.56697880897032e-09 116.708961266281 28.2217406740943 4.13542745693967 4.548976521635e-05 -234.817360150308 67.795790853372 -3.46359791949574 0.000606768873842227 DCAF15 other 0.000111177860739044 1 0.487377344527973 4.13542745693967 -3.46359791949574 4.0083241430101e-06 136.876716664652 56.3289597657538 2.42995285611272 0.0156591734303073 -498.347364435367 135.316471771443 -3.68282854194651 0.000271367371179468 CC2D1A other 0.0395781925880818 1 1 2.42995285611272 -3.68282854194651 0.000317951883536735 41.1573703078871 10.3403127016078 3.98028294651935 8.5326107052788e-05 -1.56570464541778 33.5348252897674 -0.0466889161308835 0.962790471091628 MATN3 other 1 1 0.89123118816637 3.98028294651935 -0.0466889161308835 5.02757378148899e-09 190.438524756824 49.9517431361769 3.81245003277777 0.000165049904485001 -250.889482823124 99.3172244223671 -2.52614271373678 0.0120143303028097 TRIM21 other 5.91946537032513e-05 1 1 3.81245003277777 -2.52614271373678 0.712808332213255 -2.83668909325606 7.69208300890347 -0.368780353770576 0.712536081299661 -15.321456982436 19.3344467970728 -0.792443515102569 0.42869103628321 SPATA6 other 1 1 1 -0.368780353770576 -0.792443515102569 0.000729754647926465 250.131000586444 68.2877811931539 3.66289541431931 0.000291737873587758 -84.0071071518338 173.295799201316 -0.484761359127025 0.62817729088165 LRRC41 other 1 1 1 3.66289541431931 -0.484761359127025 0.421641824731305 -3.34830131181598 2.56097868530019 -1.30743037067624 0.192017050107357 -2.00986918548285 6.30387567217567 -0.318830714627526 0.750065524364119 CCT6B other 1 1 1 -1.30743037067624 -0.318830714627526 4.6121857228036e-19 354.810617661283 72.1305663870848 4.91900501317584 1.39376356329303e-06 -478.375067537951 103.732337693546 -4.6116291040428 5.78432379929575e-06 DHX30 other 6.64246987798175e-15 0.085683188438968 0.016495191771573 4.91900501317584 -4.6116291040428 7.34963557544356e-30 559.804679646629 75.9725235326367 7.3685150053775 1.48944284251893e-12 -721.200586671239 122.278956146503 -5.89799430252878 9.37898914159076e-09 RAF1 og 1.11052993544952e-25 0.00014256063495218 2.08626258951626e-08 7.3685150053775 -5.89799430252878 0.594046807402401 -23.0037887959312 48.5192670365891 -0.474116576793786 0.635740117262777 -79.8337508538656 78.1650676653442 -1.02134819604668 0.307861011783673 SLC6A11 other 1 1 1 -0.474116576793786 -1.02134819604668 0.51617389419459 1.89867398576208 14.555600488922 0.130442848249862 0.896298286645973 25.0886559739257 23.4274649716791 1.07090784275016 0.285020436876193 PPARG other 1 1 1 0.130442848249862 1.07090784275016 5.41600842540077e-06 616.54698344627 247.704769136502 2.48903961597329 0.0133182929699771 -1067.53660862852 398.684671695947 -2.67764648208665 0.00779785827057399 NUP210 other 0.0529198183245909 1 1 2.48903961597329 -2.67764648208665 0.0454806162409286 -14.2738868444182 5.78059306709253 -2.46927723137543 0.0140603308057894 -6.08342267830709 19.8461337836302 -0.306529359553391 0.759400979823954 FCRLA other 1 1 1 -2.46927723137543 -0.306529359553391 0.00317774526348538 28.8215487657974 8.42934800108292 3.41919075616462 0.000709383894021294 1.34701587787813 28.9399316292661 0.0465452335939845 0.962904715754988 HSD17B7 other 1 1 1 3.41919075616462 0.0465452335939845 2.35365906710376e-21 391.743393521752 37.3670766729725 10.48365107472 4.67615587055169e-22 17.9977992921484 168.904905349716 0.106555811714788 0.915214046993112 ENOSF1 other 3.44599224014662e-17 1 6.99459395117122e-18 10.48365107472 0.106555811714788 0.0100234926396168 53.3551177932276 17.7722405869021 3.00216044973809 0.00290614052369922 -7.00386872036382 82.472372138367 -0.0849238179861392 0.932378601035249 EMILIN2 other 1 1 1 3.00216044973809 -0.0849238179861392 2.09604747623782e-25 324.739014634575 41.8072263633903 7.76753310090291 1.09499374825286e-13 -326.11753885049 83.4028164171476 -3.91015019468144 0.000112642566029098 ARFIP2 other 3.12981809151831e-21 1 1.55740960814004e-09 7.76753310090291 -3.91015019468144 1.30881223616203e-11 127.789548083697 30.7884150283805 4.15057247883341 4.25969545814427e-05 -198.318110331104 61.2752853636156 -3.23651059565466 0.00133710100758051 TRIM5 other 1.67828993043057e-07 1 0.457278307431787 4.15057247883341 -3.23651059565466 0.000622112791736751 259.343973625343 181.142241128842 1.43171450242176 0.153204571485214 -877.063430806689 360.510357754473 -2.43283836911009 0.0155302622147064 TRIM22 other 1 1 1 1.43171450242176 -2.43283836911009 2.67711348970521e-13 55.6357833302935 12.1383161378617 4.58348445520833 6.56530400209166e-06 -84.9092042069424 24.2151857590316 -3.5064444705023 0.000519021777478213 RRP8 other 3.56939541582396e-09 1 0.0746409411997801 4.58348445520833 -3.5064444705023 7.9044468367875e-11 67.6367235404732 19.8243334044028 3.41180316940451 0.00072818839384333 -149.998757916318 39.5483121780972 -3.79279796419202 0.000178064669277213 TIMM10B other 9.92166166953567e-07 1 1 3.41180316940451 -3.79279796419202 4.27653169530857e-11 366.591660717386 51.0683910845396 7.17844547149573 5.03730578317335e-12 229.781246583184 288.334394222179 0.796926246704107 0.42609033132291 EFR3A other 5.41579973893878e-07 1 6.99832892456274e-08 7.17844547149573 0.796926246704107 4.91131047648165e-05 150.56101347689 34.4406314075856 4.37161013963666 1.67430585570918e-05 -113.529188906139 140.977119428225 -0.805302231784778 0.421248907815012 PTCD3 essential 0.4388747041784 1 0.185044283172979 4.37161013963666 -0.805302231784778 3.56003741297557e-06 304.446023536327 63.6443558734127 4.78355102126988 2.64317363233888e-06 -364.060792077388 260.517812600915 -1.39745067119495 0.163255350363147 IMMT other 0.0352835308000009 1 0.0307982591640126 4.78355102126988 -1.39745067119495 9.5422999154213e-05 86.4446317510768 24.8756593959897 3.47506895696654 0.000581856666617233 -239.192408110019 101.824463205163 -2.34906623203186 0.0194341107619708 MRPL35 essential 0.82397759769663 1 1 3.47506895696654 -2.34906623203186 0.287024376195113 -0.232366344714999 20.838097161723 -0.0111510347087654 0.991109916401666 -53.1152479254522 37.3012258341825 -1.42395448775782 0.155437054264286 IQCA1 other 1 1 1 -0.0111510347087654 -1.42395448775782 6.96388495426678e-06 17.5345501509479 28.1046342830161 0.623902448769605 0.533138939312906 -210.3678570022 50.8685003657147 -4.13552307400019 4.53682858352584e-05 ILKAP other 0.0674243341272109 0.655390257176142 1 0.623902448769605 -4.13552307400019 1.76762377301457e-05 202.631583750597 66.1848171300944 3.06160223049796 0.00238936197326474 -228.055487154831 119.792428554088 -1.9037554368627 0.0578445815340844 PER2 other 0.16502535544864 1 1 3.06160223049796 -1.9037554368627 0.145214323283113 -94.3829343919851 70.4585659911202 -1.33955230374516 0.181344480465748 -241.697963636013 127.645855603913 -1.89350419950966 0.0591955646802349 RAMP1 other 1 1 1 -1.33955230374516 -1.89350419950966 5.03301096312875e-05 7.12712539061062 15.5551730117393 0.458183614237648 0.647133472472064 -107.648986686983 28.1543718401839 -3.82352649521161 0.000158293801706784 SCLY other 0.448994908020716 1 1 0.458183614237648 -3.82352649521161 0.000697920813983942 84.9304823460085 43.7731589688229 1.94024110543403 0.0532286181452402 -195.462546426535 88.6646925370442 -2.20451389198548 0.028199553560044 PTPRE other 1 1 1 1.94024110543403 -2.20451389198548 0.000251261157591161 814.980694664707 237.801689883874 3.42714425226619 0.000690166671897256 -885.676191822463 578.235386961005 -1.5316879800063 0.12659363649945 RAN essential 1 1 1 3.42714425226619 -1.5316879800063 5.75864233884623e-16 268.512807521251 30.3203900340115 8.85584938782284 6.24325623556544e-17 68.2084318527273 207.840406556266 0.328176955496197 0.742996599060852 PRKAA1 other 8.02697155611776e-12 1 9.11390545267843e-13 8.85584938782284 0.328176955496197 1.27555077444364e-05 102.387382949577 21.474618280299 4.76783249942597 2.85394405014616e-06 -54.1205244046615 147.204352879739 -0.367655733990938 0.713377640776406 CARD6 other 0.120641592246879 1 0.0331542680305479 4.76783249942597 -0.367655733990938 4.44834316591878e-05 217.690500816936 47.8945293019766 4.54520597633165 7.80814603015165e-06 3.02614103630269 90.9192453057246 0.0332838336495975 0.973469126676421 RAP1GAP2 other 0.399194315709551 1 0.0883257478930755 4.54520597633165 0.0332838336495975 1.21439507415766e-09 730.81767145473 118.907625366172 6.14609592281574 2.37536195294415e-09 -489.153613315324 225.8593219908 -2.16574462813294 0.0310736678573107 CLUH other 1.46237454830066e-05 1 3.13025198158981e-05 6.14609592281574 -2.16574462813294 1.54635062997338e-13 179.659187347343 24.6628591206783 7.28460501956604 2.5597321516901e-12 -146.9226603354 47.0682390650119 -3.1214819856011 0.00196460472485612 INPP5K other 2.07133666884934e-09 1 3.57415400340489e-08 7.28460501956604 -3.1214819856011 6.77928622547721e-16 619.703010784109 70.1631263402729 8.83231753070281 6.89475140791413e-17 18.455093373421 132.091489420918 0.139714477097103 0.888973480864085 MYBBP1A essential 9.43608849724173e-12 1 1.00622002047099e-12 8.83231753070281 0.139714477097103 5.39630761844917e-09 558.189552555847 102.746991514596 5.43266079451635 1.10124401718769e-07 -586.671577536091 195.306360212253 -3.0038529052434 0.00287617572339037 RPA1 essential 6.34497849777253e-05 1 0.00136906656216774 5.43266079451635 -3.0038529052434 0.1969457310395 454.771178566031 268.296940472314 1.69502931254246 0.091042645860938 363.078304174722 508.473796027637 0.714055093912819 0.475713615436145 SERPINF1 other 1 1 1 1.69502931254246 0.714055093912819 9.03005811833881e-10 353.143086686454 53.1749820210718 6.64115103125965 1.3361656625065e-10 -33.5860335483592 100.837401270756 -0.333071193080216 0.739298656433557 UBE2G1 other 1.09390124045556e-05 1 1.81130617209382e-06 6.64115103125965 -0.333071193080216 1.58300320861251e-17 189.107038178781 20.4600156009295 9.24276119174561 3.46702417701604e-18 23.0700661936655 82.2586507494575 0.280457629483032 0.779307653969662 EEFSEC essential 2.24628155302116e-13 1 5.10103267164369e-14 9.24276119174561 0.280457629483032 3.23925674782748e-15 518.751518308887 90.941912356288 5.70420727768014 2.6677904575965e-08 -349.073331270967 168.738848662361 -2.06871940894564 0.0393777394865483 TBC1D14 other 4.46531542688018e-11 1 0.000339849826393219 5.70420727768014 -2.06871940894564 7.12763732761335e-09 31.2363000099954 11.5524604111951 2.70386557479353 0.0072201788339148 -67.676689084851 21.3389271046167 -3.17151320462635 0.00166339589459709 TMEM128 other 8.32935698104896e-05 1 1 2.70386557479353 -3.17151320462635 0.0447118976035811 8.67614054138124 12.2033944904657 0.710961245099446 0.477629382769129 -54.9976060192831 26.477728732705 -2.07712702907748 0.0385922787347062 COQ3 other 1 1 1 0.710961245099446 -2.07712702907748 0.108179711042274 -34.8229040503407 59.6973505269636 -0.583324113096311 0.560088595889314 -274.033764017413 129.525457408517 -2.11567493757712 0.0351495443105101 PNISR other 1 1 1 -0.583324113096311 -2.11567493757712 0.000690781413647706 45.5314708342597 15.0854961334912 3.0182282658358 0.00274746355153166 -51.7458191713521 34.206976472418 -1.51272706645313 0.131339052188013 POPDC3 other 1 1 1 3.0182282658358 -1.51272706645313 2.5233923087867e-53 1929.75354150794 99.2633649348434 19.4407427430516 1.56614234795753e-54 617.519127226068 794.140164885923 0.777594629425113 0.437439734602574 SEC61G essential 3.8696221055244e-49 1 2.40261897600165e-50 19.4407427430516 0.777594629425113 1.16937126876245e-43 237.562239809563 14.0880598898011 16.8626653824452 8.1899245593525e-45 -25.9979441903072 120.20062445577 -0.216287929517985 0.828916966798219 LANCL2 other 1.78902110407968e-39 1 1.25404124852806e-40 16.8626653824452 -0.216287929517985 0.00696378795827316 49.2629351641028 17.4877372645572 2.81699881573274 0.00515548395001085 -119.658036454513 104.012461371879 -1.15042019846733 0.250848997353352 FIGNL1 other 1 1 1 2.81699881573274 -1.15042019846733 0.689125573026324 -6.86240898118661 8.39498851910131 -0.817441139505124 0.414298166131062 -18.288436559001 49.9311835402567 -0.366272843187385 0.714408941907285 DDC other 1 1 1 -0.817441139505124 -0.366272843187385 1.03977451433662e-14 386.061996054804 62.6128187719104 6.16586193733223 2.1180165962389e-09 -421.383527771827 131.06404769204 -3.21509624639358 0.00143753656781195 GRSF1 essential 1.423971197384e-10 1 2.79472289873723e-05 6.16586193733223 -3.21509624639358 0.00604885761703781 -115.972581408525 41.300155502798 -2.8080422457651 0.00529141090239654 41.7284381700556 86.4513953640395 0.48268090982616 0.629653380064357 ENAM other 1 1 1 -2.8080422457651 0.48268090982616 0.00612396211783985 -1458.68646835898 510.134631058572 -2.85941471045022 0.0045237961391761 392.532346055611 1067.83740016536 0.367595615207731 0.713418549781145 JCHAIN other 1 1 1 -2.85941471045022 0.367595615207731 6.05613287060197e-12 719.385744022126 103.802149147018 6.93035500645789 2.34215844861953e-11 -58.4207959481169 224.907393446307 -0.259754893126996 0.79522093684229 ANKRD17 other 7.83542470798482e-08 1 3.21789149255837e-07 6.93035500645789 -0.259754893126996 4.79121554195327e-14 164.42367151928 25.0187405378028 6.57202033295158 2.02287521148866e-10 -120.195873896531 52.3703846489725 -2.29511153492911 0.0223754931533415 UTP3 essential 6.47197395407048e-10 1 2.73189297311543e-06 6.57202033295158 -2.29511153492911 4.76675523337806e-06 4014.1509028721 1050.0655941242 3.82276204966041 0.000158853704377236 -6878.64081822089 2587.1285764144 -2.65879356786908 0.00824018998101032 ITGB4 other 0.0468143031470059 1 1 3.82276204966041 -2.65879356786908 6.52687480397189e-08 344.269162172461 65.8675819227906 5.22668590712818 3.13670359705924e-07 -308.225059641724 162.28310346069 -1.89930469080772 0.0584320164956221 WBP2 other 0.00072689804691835 1 0.00382583737733315 5.22668590712818 -1.89930469080772 7.00956847410494e-07 96.8655948394632 20.1642373462012 4.80383131662116 2.40534781970335e-06 -88.4999622008932 49.6802056479811 -1.78139283134166 0.0758056373221152 UNK other 0.00733130766706636 1 0.0280704090559381 4.80383131662116 -1.78139283134166 0.0109207518616096 211.254972898386 78.0905382476342 2.70525697016547 0.00719418924985556 -175.8347869522 192.299564137297 -0.914379539761504 0.361212417915623 TRIM47 other 1 1 1 2.70525697016547 -0.914379539761504 0.00370665596824993 18.0766166990503 45.234153893645 0.399623186089701 0.689701507798959 -299.379811228685 96.7133771012246 -3.09553673133905 0.00213872596422888 ZRANB2 other 1 1 1 0.399623186089701 -3.09553673133905 3.09535444254229e-10 2806.4259261345 409.83181681039 6.84775025027621 3.84521651140717e-11 86.9350420109223 782.286131929231 0.111129468442101 0.91158334952238 EIF5A essential 3.81719109854315e-06 1 5.26410140411642e-07 6.84775025027621 0.111129468442101 2.21877170918598e-11 464.780577335736 64.4516643235224 7.21130450569464 4.04923113286868e-12 162.617220723098 123.218990740986 1.31974154101724 0.187867645005357 KDM6B other 2.82982143789579e-07 1 5.63571989072663e-08 7.21130450569464 1.31974154101724 0.00844539836783319 -14.4283257810293 7.42970821907075 -1.94197744455083 0.0530171315577386 -35.705679576898 14.1818118205026 -2.51770930462343 0.0122999591859397 CLEC10A other 1 1 1 -1.94197744455083 -2.51770930462343 1.66752393876789e-06 57.4411947174603 13.8469624818583 4.1482884634603 4.29695682928859e-05 -98.0431285399296 30.9090072615084 -3.1719921545984 0.00166073945713519 SLC52A1 other 0.0169620535051469 1 0.461149406919252 4.1482884634603 -3.1719921545984 2.60139226643617e-08 26.9121512609152 4.44607970948627 6.05300692281668 3.97646917754375e-09 6.40903566848211 8.45036265857573 0.758433209014762 0.448749905838092 GUCY2D other 0.000296142495611093 1 5.20320991881599e-05 6.05300692281668 0.758433209014762 1.38836303237152e-19 556.685813840185 56.6991832850684 9.818233378095 4.62426179153726e-20 -150.96091869818 108.227284842903 -1.39485083560312 0.164028256399633 GPS2 other 2.00923898044806e-15 1 6.87119059604521e-16 9.818233378095 -1.39485083560312 0.00897384199433063 243.236356198795 142.529540510157 1.70656802321945 0.088872518253562 -680.358186095369 272.060094794755 -2.5007643499082 0.0128921968583311 XAF1 other 1 1 1 1.70656802321945 -2.5007643499082 1.14019465644577e-06 60.3674399193672 11.977357940075 5.0401299035561 7.79820818031597e-07 45.8196720540133 22.8623562870134 2.00415352988093 0.0458960260667508 DLG4 other 0.0117576872972688 1 0.00933757447511034 5.0401299035561 2.00415352988093 1.38767955118785e-12 67.5011372251704 8.78338906248522 7.68509020208098 1.91625553197809e-13 -8.39314728189706 47.992421086946 -0.174884848311602 0.861281410231362 RIDA other 1.82285585844035e-08 1 2.71571733991935e-09 7.68509020208098 -0.174884848311602 0.000586840761963916 101.041480560842 25.8893950735111 3.90281349849784 0.000116092767180459 19.5253769741089 153.151917794544 0.127490254482498 0.898632966418773 VPS13B other 1 1 1 3.90281349849784 0.127490254482498 0.427651521997562 64.7805472058279 65.2753204611277 0.992420209478796 0.321744755154691 323.37428107808 349.892133903741 0.92421134899547 0.356074854281872 MATN2 other 1 1 1 0.992420209478796 0.92421134899547 0.559392865274008 -7.08599725415242 18.2432836194315 -0.388416767615502 0.697965923430665 -28.8880700998734 26.7871902906548 -1.07842852447095 0.281654796280655 REEP2 other 1 1 1 -0.388416767615502 -1.07842852447095 0.000209484118154773 1.8910037280603 10.2586549521083 0.184332520870261 0.853869728030318 -58.2858523049404 15.3188441060252 -3.80484662560248 0.000170068432361981 PCBD2 other 1 1 1 0.184332520870261 -3.80484662560248 3.18047949378135e-16 188.047278083249 21.017782903432 8.94705587869318 3.27922836381021e-17 55.1967029700416 66.7871173582216 0.826457334188969 0.409174260790202 SDF2 other 4.44535618845819e-12 1 4.79390394505414e-13 8.94705587869318 0.826457334188969 7.31341950216604e-09 670.519185689074 119.1873101898 5.6257598616942 4.08044024932789e-08 -794.337550291924 377.023752310279 -2.10686341490286 0.0359198493279795 FLOT2 other 8.54134263657972e-05 1 0.000515767647515045 5.6257598616942 -2.10686341490286 1.50399955270026e-37 424.837806342725 28.7175099326 14.793685362687 6.09510351253354e-38 -47.1260911736181 90.836166593437 -0.518803169937193 0.604263436444952 ERAL1 essential 2.29329851795736e-33 1 9.31088012574623e-34 14.793685362687 -0.518803169937193 0.0137451054588669 44.7648952983984 20.5410437961993 2.17929019296874 0.0300413509846131 -50.7355396247842 54.9866638339428 -0.922688086296765 0.356867113894777 PRMT7 other 1 1 1 2.17929019296874 -0.922688086296765 4.70062361395307e-21 272.388599321756 35.4622250534465 7.68109160976866 1.95352614602757e-13 -333.667722496989 96.7259239012529 -3.44962042272793 0.000636850948377748 NIP7 essential 6.8709015365152e-17 1 2.76795119630646e-09 7.68109160976866 -3.44962042272793 5.97391472332709e-16 119.62933800063 17.010080380619 7.03284965877842 1.23768706713474e-11 -100.468510831799 46.3962917716029 -2.1654426893938 0.0310946337051235 TERF2 essential 8.32405277548397e-12 1 1.70949337712651e-07 7.03284965877842 -2.1654426893938 1.59664388957936e-19 304.602007465038 39.4334460750608 7.72445823997308 1.46727565935916e-13 -295.10265235746 107.557732163504 -2.74366748369945 0.00641940042200966 VPS4A other 2.30842773555384e-15 1 2.08235761576252e-09 7.72445823997308 -2.74366748369945 7.93899036997583e-07 329.641898110554 65.0337993801049 5.06877810081318 6.78642041831795e-07 52.6698035394123 178.784123845014 0.294600003661797 0.768490479941707 MTSS1L other 0.00827877915781079 1 0.00814845499627436 5.06877810081318 0.294600003661797 0.318405893171107 9.26055926460129 6.34159027349093 1.46028974834786 0.145191530940297 0.375878439264265 23.4443775589687 0.0160327753773301 0.987218235433231 HSPA12B other 1 1 1 1.46028974834786 0.0160327753773301 8.79679094261353e-08 77.3187002459322 14.9975961679051 5.15540619845427 4.46374830145246e-07 -76.2742480119794 58.3150340222029 -1.30796885041581 0.1918315563721 ANKEF1 other 0.000974244596894449 1 0.00540783106720965 5.15540619845427 -1.30796885041581 9.45363319453704e-07 98.4924891740059 24.4721050356149 4.02468398328084 7.12682228358085e-05 -205.872406720538 89.5501349508717 -2.29896255135162 0.0221510141874526 PCED1A other 0.00981098052929054 1 0.749955508901212 4.02468398328084 -2.29896255135162 0.392133119861289 -8.44807581898734 8.5472445228671 -0.988397581979264 0.323711788382202 -39.0839665506988 33.2341829695167 -1.17601707213768 0.240470473069452 SNAP25 other 1 1 1 -0.988397581979264 -1.17601707213768 1.21755350179838e-05 99.6174177863529 23.6760549491935 4.20751759531401 3.37068753877068e-05 -116.383547753562 94.1711041480365 -1.23587324165391 0.217426510101338 BTBD3 other 0.115387545365433 1 0.3646746848196 4.20751759531401 -1.23587324165391 0.000374022523616251 465.703216198069 166.142218925562 2.80303958385629 0.00537116707217511 -1255.41394016672 628.375741911865 -1.99787142696989 0.0465766916864673 PCNA essential 1 1 1 2.80303958385629 -1.99787142696989 2.83688186088967e-15 135.458992162377 16.6431125792106 8.13904199215613 9.26387996516394e-15 -38.7479060075646 72.2034097057213 -0.536649254730339 0.591887521006423 NXT1 other 3.91574803258601e-11 1 1.33140482859336e-10 8.13904199215613 -0.536649254730339 1.0554363704611e-17 60.6367650350837 6.69864182656806 9.05209841114165 1.45751485276623e-17 -10.8178918333372 27.9395738640528 -0.387188862864352 0.698876208047602 POLR3F other 1.50083051879569e-13 1 2.13511350781725e-13 9.05209841114165 -0.387188862864352 1.16278105712416e-12 725.68213921562 96.3535741745097 7.53145013490947 5.27174565857042e-13 80.9658877584394 410.985057692819 0.197004456105933 0.843950299920844 RIN2 other 1.52952220254112e-08 1 7.42103636356957e-09 7.53145013490947 0.197004456105933 4.40958321280982e-25 384.397015974191 38.3668736190744 10.0189819944851 9.93330116260742e-21 -389.360395200257 140.394898813608 -2.77332295183447 0.00587417901507285 PTPRA other 6.57557048694201e-21 1 1.47936654214712e-16 10.0189819944851 -2.77332295183447 1.18712811609681e-07 326.439448983605 56.6410986862732 5.76329655594616 1.94020434964038e-08 87.0295728818412 197.228487171696 0.441262690445311 0.659320828249155 DAP3 essential 0.00130429766115556 1 0.000248578981275926 5.76329655594616 0.441262690445311 0.00229642944661627 482.547541325185 140.813740347692 3.42684982398518 0.000690367677291585 -418.209820808449 472.041247532393 -0.885960332904487 0.376304190721522 NES other 1 1 1 3.42684982398518 -0.885960332904487 0.887017635597618 -12.2162829328148 47.5498665850808 -0.256915188415013 0.797409353141399 -65.4384154435032 159.398495398239 -0.410533457546214 0.681689409565051 BCAN other 1 1 1 -0.256915188415013 -0.410533457546214 6.02811056738452e-09 320.250909464151 50.6422510144437 6.32378899138612 8.57956369663012e-10 -122.487407983418 177.772945115222 -0.689010399777248 0.491315984163802 ARHGEF11 other 7.0703708844853e-05 1 1.14391322767169e-05 6.32378899138612 -0.689010399777248 0.637303521356636 127.151881715624 142.096771260426 0.894825973790691 0.371552678178007 148.040443030055 494.791447865547 0.299197659273776 0.764983458744035 RAB25 other 1 1 1 0.894825973790691 0.299197659273776 3.54706971718102e-13 337.366586427325 42.8914570325759 7.86558932169396 5.6950676185123e-14 -176.009942393138 150.135571925277 -1.17234003997893 0.241932581785444 DCAF8 other 4.71511977504873e-09 1 8.12913951866446e-10 7.86558932169396 -1.17234003997893 0.597029754864613 8.90301521463179 14.5681505912982 0.611128719382523 0.541548228699119 -41.8673091019613 50.7273758569855 -0.825339540921589 0.409793696806135 SYT11 other 1 1 1 0.611128719382523 -0.825339540921589 5.42275711184637e-89 165.598267494649 5.5773569383829 29.691172597367 3.27571126614776e-89 4.08965379339982 75.6872659346716 0.0540335780781109 0.956946268274192 IGHMBP2 other 8.3304394752184e-85 1 5.03214764705619e-85 29.691172597367 0.0540335780781109 0.938565314431808 0.293925122555052 2.01631005178337 0.145773772389362 0.884195647511832 -2.8902300849512 10.208552773868 -0.283118493774128 0.777276815783906 ACY3 other 1 1 1 0.145773772389362 -0.283118493774128 2.02215345696025e-09 952.040344793668 167.927423384083 5.66935599682348 3.30672734662101e-08 -1598.83448744703 850.214460955469 -1.88050728477409 0.0609854995226984 ALDH3B2 other 2.41546230433902e-05 1 0.000419359162098476 5.66935599682348 -1.88050728477409 1.18488258241276e-27 32.9886942531055 2.67999023408697 12.3092591284551 2.91219019488848e-28 0.0778756696194865 30.9186878877563 0.00251872491815298 0.99799209413419 TESMIN other 1.7812339861411e-23 1 4.41225936427554e-24 12.3092591284551 0.00251872491815298 0.0540065461464397 450.535091816265 258.402810941079 1.74353789022441 0.0822030859659472 -879.259381040417 655.65011266127 -1.34104969107917 0.180858382319663 MMACHC other 1 1 1 1.74353789022441 -1.34104969107917 9.39079394740645e-21 210.027286771477 22.1000946758182 9.50345642642371 4.99052396643424e-19 -166.941116880898 69.3082330561243 -2.40867656726601 0.0165753098330752 DPH2 other 1.37030465280555e-16 1 7.37549536999316e-15 9.50345642642371 -2.40867656726601 1.91616049636013e-05 8.24528326161185 10.3428205330848 0.797198717239336 0.425928589899998 -116.763060942358 26.2430250779996 -4.44929883636944 1.19179871975462e-05 TOE1 essential 0.178145441346601 0.175039477970362 1 0.797198717239336 -4.44929883636944 0.00196321000719063 173.353263695157 141.66619942329 1.2236741325797 0.221978252234855 -1103.82269156929 359.415854514224 -3.07115748430516 0.00231576527301979 NASP essential 1 1 1 1.2236741325797 -3.07115748430516 0.00165603494587269 29.4718438183965 12.7402221977702 2.31329119389728 0.0213422415936589 -74.59730746109 32.325995560483 -2.30765692340445 0.0216579116725537 MUTYH ts 1 1 1 2.31329119389728 -2.30765692340445 1.55273323398016e-28 428.624719942336 35.8430768204404 11.9583684762772 1.87154264325602e-27 -243.288146671571 187.547757127255 -1.29720637771474 0.195503476582082 CTNNBL1 essential 2.33841625037413e-24 1 2.83201832777501e-23 11.9583684762772 -1.29720637771474 1.0416332858583e-07 111.766599667313 20.2641669714418 5.51547960618491 7.21252293982535e-08 -50.4701872131352 92.3326341156077 -0.546612665137903 0.585028192040419 LPIN3 other 0.00114850486098736 1 0.000903440623442523 5.51547960618491 -0.546612665137903 0.000232778837332833 9.90668160262875 2.77553548260317 3.5692865988286 0.000412809332322229 -15.0115810462641 12.6182167876203 -1.18967531616607 0.23505596208754 ZSWIM3 other 1 1 1 3.5692865988286 -1.18967531616607 0.128966624320041 91.7007306852258 48.9400833744425 1.8737346641529 0.0618810450576621 -80.0852192739074 233.558319801789 -0.34289174259291 0.731905745969842 RBM38 other 1 1 1 1.8737346641529 -0.34289174259291 0.851444801950753 13.4922182197763 24.0646107501866 0.560666381012277 0.575422292885614 25.2010146433604 125.929049675776 0.200120740275928 0.84151487859468 VSTM2L other 1 1 1 0.560666381012277 0.200120740275928 4.7105776335121e-09 106.040594698137 19.3444631482598 5.48170263942821 8.57261588030909e-08 -154.609188834491 86.3177883453991 -1.7911625378517 0.0742151231649694 OSER1 other 5.55329997214741e-05 1 0.00107011964033898 5.48170263942821 -1.7911625378517 4.21528430611617e-18 742.555240992958 86.6116409919011 8.57338843242092 4.41008764762616e-16 -731.336168670303 386.473650785143 -1.89233125514392 0.0593521390268237 SERINC3 other 6.01563223325839e-14 1 6.40300625558842e-12 8.57338843242092 -1.89233125514392 0.0327550506054168 39.1709289230264 17.1127692815336 2.28898831501782 0.022731165140922 -59.4940885182701 80.3415800521906 -0.740514295083843 0.459530980363034 PPP1R3D other 1 1 1 2.28898831501782 -0.740514295083843 0.995584201556829 -0.234133918280847 2.90530073702796 -0.0805885309210226 0.935819564662532 0.0494441759304014 3.99265138800579 0.0123837949085501 0.990127130753506 BHMT2 other 1 1 1 -0.0805885309210226 0.0123837949085501 3.63849461212549e-12 262.143612949427 61.1543886629672 4.28658709016204 2.4042088662396e-05 -336.425119764916 84.3076284753894 -3.99044696012441 8.18106379101744e-05 AP3B1 other 4.73222609253042e-08 1 0.262755986991325 4.28658709016204 -3.99044696012441 0.00146647567069135 21.5822413407268 24.0326716589464 0.898037540187196 0.369840714981185 -95.5695800283462 33.0580463429516 -2.89096273375885 0.00410328340383426 ZBED3 other 1 1 1 0.898037540187196 -2.89096273375885 0.00200784205681037 138.629247960222 47.5360141068547 2.91629936932873 0.00379392523711576 -135.008479320899 111.217939887537 -1.21390918998697 0.225683173029667 PATJ other 1 1 1 2.91629936932873 -1.21390918998697 0.0538329162963006 64.9259268626454 28.0036829379702 2.31847814469475 0.0210532161859942 -6.58439806991397 65.5360866054036 -0.100469808482142 0.920034267308266 KANK4 other 1 1 1 2.31847814469475 -0.100469808482142 1.2375029574792e-06 82.2485601048577 23.1778891732731 3.54857853922695 0.00044532145050033 -130.010978136169 48.8063488129235 -2.66381282964857 0.00811720920447547 FBXO44 other 0.0127351429354185 1 1 3.54857853922695 -2.66381282964857 2.91099514647376e-06 8.4287470676593 2.77365954768642 3.03885423670326 0.00257050679779555 -16.5984994887726 5.55417102374475 -2.98847468286664 0.00302073403909198 RSG1 other 0.0290662865375405 1 1 3.03885423670326 -2.98847468286664 0.0174830487634614 -16.421450180913 16.9976348815385 -0.966102066279154 0.334724950289486 -98.4160115424535 34.375901983326 -2.86293612281621 0.00447508766954842 CASP9 other 1 1 1 -0.966102066279154 -2.86293612281621 2.33323058721767e-10 228.206849930077 63.7200217577168 3.58139943513814 0.00039483845388414 -402.293981575158 92.2529116119034 -4.3607727338467 1.74967534944769e-05 DCTN4 essential 2.88900611309292e-06 0.256012497131187 1 3.58139943513814 -4.3607727338467 0.197030571589829 5.40495458071498 9.6706461076709 0.558903150889544 0.576619947892223 -24.5282694311459 18.1018368664603 -1.35501549439951 0.176371377653803 ATP8A2 other 1 1 1 0.558903150889544 -1.35501549439951 1.12431095659497e-07 36.6157355310353 10.4409832618376 3.50692407149698 0.000521451672273318 -41.0680002914431 16.9313329639746 -2.42556214438786 0.0158648024310329 ZMYM5 other 0.00123696691444578 1 1 3.50692407149698 -2.42556214438786 8.57613104283079e-10 53.7751487521685 11.7462503347613 4.57806935997515 6.73405678356382e-06 -52.5488785907111 20.4549274090274 -2.56900831471637 0.0106533396877342 USPL1 essential 1.04002741156409e-05 1 0.0765258212884193 4.57806935997515 -2.56900831471637 1.27612993366882e-11 123.131153698848 31.0401743275076 3.96683189983665 9.06458839701446e-05 -180.63363159246 50.3291594986968 -3.58904526504435 0.000386001123793868 XPO4 other 1.63663663993026e-07 1 0.943804943897146 3.96683189983665 -3.58904526504435 2.17861475687721e-10 210.164641597381 89.593893270793 2.34574739332031 0.0196029972220299 -718.727225532263 147.296728283428 -4.87945138977757 1.68532954606014e-06 POMP other 2.70104657557637e-06 0.0251788234181386 1 2.34574739332031 -4.87945138977757 1.16617429294308e-14 62.8990015167084 11.5250935697038 5.45756970529524 9.70880722206992e-08 -80.4440137559483 21.5730532734502 -3.72891183905572 0.00022751165122187 CDK8 other 1.59485996302895e-10 1 0.00120971737986991 5.45756970529524 -3.72891183905572 0.0205216542499537 -34.7333225384907 23.5123003632761 -1.47724050823801 0.140597728497983 -113.821122998108 40.9443340166847 -2.77989923958041 0.00576034522145057 ALOX5AP other 1 1 1 -1.47724050823801 -2.77989923958041 0.00199610802605305 40.4839283337256 12.2018728339305 3.31784545575246 0.00101197806869355 57.1933209749688 22.8398711984611 2.50409997841066 0.0127752199529535 WASF3 other 1 1 1 3.31784545575246 2.50409997841066 0.00282671391700585 67.9770356594158 21.090647658256 3.2230890563859 0.00140097210219796 76.890473256135 67.9927397694969 1.13086299385497 0.258973019585795 CHRM3 other 1 1 1 3.2230890563859 1.13086299385497 0.0203242938525085 29.5601319439543 13.4829944051139 2.19240111326774 0.0290985075747453 46.697927433329 25.5586160061012 1.82709139736602 0.0686536264322804 MYH8 other 1 1 1 2.19240111326774 1.82709139736602 1.71791213340243e-13 795.052371212632 101.066346405282 7.86663809953537 5.69862728845261e-14 358.550376788953 190.852914684703 1.87867383309966 0.0612007941635899 MYH10 other 2.29891001691913e-09 1 8.13365072880841e-10 7.86663809953537 1.87867383309966 4.1321717735116e-12 132.305450439087 17.8731822738178 7.40245628406641 1.2053505401446e-12 -36.0662456859342 33.5215825433001 -1.07591118764596 0.282782572279588 PEMT other 5.36810435096892e-08 1 1.69026306244477e-08 7.40245628406641 -1.07591118764596 1.48571158271691e-16 150.023662213654 17.7290282410778 8.46203526632395 1.00431423037631e-15 -95.0185415003689 33.1385941986974 -2.8673075547696 0.00441884064051525 SCO1 other 2.08400763707701e-12 1 1.45484959412312e-11 8.46203526632395 -2.8673075547696 3.26405817970356e-13 484.889440053806 67.1167336835378 7.22456850090633 3.70265510793986e-12 -371.467758053281 143.110223380602 -2.59567590126221 0.00987563578206302 MPRIP other 4.34185019064167e-09 1 5.15631750331705e-08 7.22456850090633 -2.59567590126221 0.0033936632681807 641.259216857483 190.031229355562 3.37449386099399 0.000830471084967132 -223.15911199693 646.324617814737 -0.345274040081352 0.730115208057646 CHI3L1 other 1 1 1 3.37449386099399 -0.345274040081352 0.498843950673901 122.571555623995 103.831478170005 1.18048551156429 0.238683893247444 3.92116472643303 353.146378481836 0.0111035110802778 0.991147781032051 MYBPH other 1 1 1 1.18048551156429 0.0111035110802778 0.197100109814136 52.2970963005069 31.8145659464687 1.64380983190222 0.101197564760111 -78.0778661992957 108.043282558928 -0.72265359169101 0.470420541764055 PIK3C2B other 1 1 1 1.64380983190222 -0.72265359169101 1.23495476817274e-06 97.7837304406866 18.3505507281783 5.32865372212148 1.87051719371763e-07 1.25333817546381 62.3190566475912 0.0201116358765077 0.983966852086514 DSTYK other 0.0127101544740338 1 0.00230335487234389 5.32865372212148 0.0201116358765077 0.347624156317742 114.214341616165 79.3807808916399 1.43881605009751 0.151180010079301 -50.1156016488958 269.985902031018 -0.185623031691256 0.852857993503269 CHIT1 other 1 1 1 1.43881605009751 -0.185623031691256 3.69599479953696e-05 149.097224195917 34.073787854242 4.37571616145855 1.64031280189605e-05 -152.319225364345 115.71567234905 -1.31632321078239 0.189007645682628 SLC41A1 other 0.334413609462104 1 0.181352983377627 4.37571616145855 -1.31632321078239 0.225424585489756 46.4125041708817 34.0350370094957 1.36366839142654 0.173636490661158 127.375595619558 115.671649744032 1.10118249287034 0.271650041830186 LGR6 other 1 1 1 1.36366839142654 1.10118249287034 0.00126706148647628 60.6652692908911 16.8382016876952 3.6028354105785 0.000364822564461234 49.2893357333463 57.1830709804104 0.861956780009797 0.389356759586727 TMCC2 other 1 1 1 3.6028354105785 0.861956780009797 0.0016634100154177 88.2241978271854 29.4935835064116 2.9913014065587 0.00299436246183368 163.600604483726 51.7205958991896 3.1631616310571 0.00171083433342728 DCLK1 other 1 1 1 2.9913014065587 3.1631616310571 0.00148972825449222 216.577064571833 74.5025361405952 2.90697573251904 0.00390579127823262 -83.6399581928894 130.852895981221 -0.639190730672806 0.523159010284534 CCNA1 other 1 1 1 2.90697573251904 -0.639190730672806 1.10260395279042e-14 109.482219665111 18.0929578226351 6.05109572123937 4.05556033513191e-09 -80.3589762823847 32.882506591037 -2.44382149091665 0.0150774840798825 COG6 other 1.50891350939369e-10 1 5.30629514248659e-05 6.05109572123937 -2.44382149091665 6.30453839107959e-06 74.709277159607 99.5072397774899 0.750792377787445 0.453332813053617 -772.089287115266 185.059273771726 -4.17211886429238 3.89809750640916e-05 EPSTI1 other 0.0612422859309471 0.564444518928046 1 0.750792377787445 -4.17211886429238 0.115289221737844 2.96640206095592 1.42415062573998 2.08292718996251 0.038056544274107 2.64348787986636 2.5297027909213 1.04497962739078 0.296826067593269 TRPC4 other 1 1 1 2.08292718996251 1.04497962739078 0.0237863605913681 2714.69008343255 1030.93666527241 2.63322682651436 0.00887101670626905 3470.11143854052 1820.71171439809 1.90590932715985 0.0575634395190781 POSTN other 1 1 1 2.63322682651436 1.90590932715985 0.0173063665567854 3.2424713613395 4.77882767766466 0.678507696875993 0.497943302266631 -18.2399151212917 8.39331750851508 -2.17314728089188 0.0305070556447725 RFXAP other 1 1 1 0.678507696875993 -2.17314728089188 3.00409847495232e-15 7963.81950132044 1609.39780041291 4.94832259574185 1.21575307523151e-06 -13492.0017940948 3012.57687932136 -4.47855850142955 1.04906414549832e-05 TPT1 essential 4.14325261665424e-11 0.154359298368623 0.0144382835214494 4.94832259574185 -4.47855850142955 2.30187748588295e-10 51.820961827359 11.564980546487 4.48085162089616 1.03851896509616e-05 -63.1132933313294 21.5099832749797 -2.93413958181652 0.00358799260244152 GPALPP1 other 2.85133564176321e-06 1 0.116334894470071 4.48085162089616 -2.93413958181652 0.226905016104486 -10.2059078635709 8.86877798774265 -1.15076822056842 0.250694896982646 10.3679558015349 15.5672161919176 0.666012193427229 0.505887668636844 KL other 1 1 1 -1.15076822056842 0.666012193427229 6.14601974584416e-05 38.1007907814544 22.923635222648 1.66207455368212 0.0974863150774941 -121.983280626243 40.2374696839658 -3.03158428162425 0.00263334585277468 RFC3 essential 0.542570623163122 1 1 1.66207455368212 -3.03158428162425 0.00407343848093548 53.0206065459522 19.6134782961687 2.70327403152705 0.00723626056142054 -21.2300998146592 34.4272071455536 -0.616666339645304 0.537897439381716 STARD13 other 1 1 1 2.70327403152705 -0.616666339645304 1.86326496778403e-15 158.874524023887 18.937125667724 8.38957964432109 1.60082483168973e-15 -48.0755903755773 44.7049214033227 -1.07539816347835 0.283009188502031 FAM104A other 2.5804356538841e-11 1 2.31623344897186e-11 8.38957964432109 -1.07539816347835 6.00262972127926e-06 182.401586398248 37.1043541491382 4.91590786528982 1.41639565310269e-06 -20.8834578212944 88.5565314316666 -0.235820638903511 0.81372318098518 SLC39A11 other 0.0584416029663749 1 0.0167531277848986 4.91590786528982 -0.235820638903511 0.0690090630412136 128.234728241304 75.6826328081914 1.69437456762768 0.0911670585437534 -149.29463272588 146.324552794979 -1.02029789173566 0.308357939074874 EPHB2 other 1 1 1 1.69437456762768 -1.02029789173566 0.143747801246473 88.5776046453697 64.4285673629988 1.37481878413208 0.170152523204004 -124.732394206719 125.520340357793 -0.993722562025979 0.321111119325385 SRRM1 essential 1 1 1 1.37481878413208 -0.993722562025979 6.39563023177936e-15 622.510476942556 116.871032743965 5.32647365499304 1.89840772474978e-07 -591.762392533999 193.669293554554 -3.05553028914884 0.00243684807740829 BTBD2 other 8.78375856032577e-11 1 0.00233712974993946 5.32647365499304 -3.05553028914884 0.81046780981617 2.33019630410324 4.35611210928655 0.534925696502537 0.593073903969443 -0.927289972067394 8.1741096068923 -0.113442321752759 0.909751247705511 PRAM1 other 1 1 1 0.534925696502537 -0.113442321752759 0.000119529102874748 39.2897190338262 12.8381001483606 3.06039979278738 0.00239749484348017 -72.0390677982218 33.5037538131661 -2.15017899785046 0.0322900289644897 KMT5C other 1 1 1 3.06039979278738 -2.15017899785046 5.88856949791738e-07 28.7930142637301 12.1214767223786 2.37537182334993 0.0181219205552968 -80.0332152232671 22.7455760642359 -3.51862775412875 0.000496819768272937 ZNF414 other 0.00619300854095971 1 1 2.37537182334993 -3.51862775412875 0.28182423699559 -21.4955597054482 21.8361179388426 -0.984403902087897 0.325667692638947 -63.9782470418423 40.2818073003853 -1.58826654833906 0.113222944808498 PDE6B other 1 1 1 -0.984403902087897 -1.58826654833906 0.000844313232877814 215.152032615654 62.8834086961165 3.42144354253082 0.000703740431129933 -119.869241080766 164.107634271449 -0.730430620201928 0.465661424661472 HSPBP1 other 1 1 1 3.42144354253082 -0.730430620201928 1.18210033145224e-14 186.609092270616 80.6740281130623 2.31312476438004 0.021353516499392 -779.948636431714 133.686523221588 -5.83416052446015 1.33081408044083e-08 CSNK1G2 other 1.61628578319465e-10 0.000202124042537353 1 2.31312476438004 -5.83416052446015 2.42274450011962e-06 20.6359562107458 13.4970147883322 1.52892743576046 0.127276508200525 -74.2099319340106 18.7578330863454 -3.95621027185871 9.39424641648123e-05 SLF1 other 0.0243340457592015 1 1 1.52892743576046 -3.95621027185871 1.81657295589916e-14 203.001850092865 218.972943887727 0.927063620229492 0.354598785555419 -1951.98528998964 332.275712381941 -5.87459515471866 1.07137757932908e-08 CNDP2 other 2.47489899511701e-10 0.000162806536954846 1 0.927063620229492 -5.87459515471866 0.380481644309586 28.6136221079422 23.4294677763723 1.22126641463012 0.222901332690364 -29.9324639119734 94.761587486388 -0.315871279765897 0.752310063076346 MACROD1 other 1 1 1 1.22126641463012 -0.315871279765897 0.0001129427847599 149.13403608256 52.290760515583 2.85201505222164 0.00463324338576359 -466.131260366223 201.209540023656 -2.31664592201454 0.0211684006036512 WDR74 essential 0.967580837038061 1 1 2.85201505222164 -2.31664592201454 8.17326183266824e-10 372.996580791495 76.140768156747 4.89877617236047 1.54928398740203e-06 -920.453705271 305.089846102626 -3.01699226319508 0.00276239505739882 RTN3 other 9.92070521249271e-06 1 0.0182861989033062 4.89877617236047 -3.01699226319508 0.160698832019043 -108.330977506289 67.4229345718507 -1.60673779915117 0.109123432993084 -377.080657949138 256.657576595085 -1.46919745347724 0.14278680341051 RARRES3 other 1 1 1 -1.60673779915117 -1.46919745347724 0.394664587884494 -3.13947707453472 7.96073822356512 -0.394370093120427 0.693577246409092 -41.3844275668356 30.3039877060042 -1.36564296317465 0.173034748701491 HRASLS2 other 1 1 1 -0.394370093120427 -1.36564296317465 0.712573552433906 95.7212109381532 295.429430013766 0.32400702575127 0.746144384557758 755.919015758889 924.636392401955 0.817531109493989 0.41423325423638 MYH11 other 1 1 1 0.32400702575127 0.817531109493989 0.00290971100779166 118.038597890304 37.9039512571852 3.1141502132427 0.00201151017690941 -66.1223631112191 118.631961435224 -0.557373934572628 0.577661630804379 FOPNL other 1 1 1 3.1141502132427 -0.557373934572628 7.49819455152855e-19 208.78662810095 21.8015992941414 9.57666569704618 2.92404915902082e-19 -107.05892228178 123.938413075327 -0.863807431653262 0.38834270560886 MED10 other 1.07764052094568e-14 1 4.3249611111077e-15 9.57666569704618 -0.863807431653262 0.0157790024489807 93.1772495462814 32.315802076196 2.88333395923712 0.00420479532206383 -4.82232410986165 209.336100529609 -0.0230362756240392 0.98163587630239 PDZD2 other 1 1 1 2.88333395923712 -0.0230362756240392 1.77401587379303e-06 214.548061254238 45.4180961688605 4.72384532492439 3.48239818037094e-06 -142.022252228752 126.729871047643 -1.12066911340389 0.26327701317461 MORC2 other 0.0179849729285137 1 0.04027393495599 4.72384532492439 -1.12066911340389 0.0894631349258491 35.7947596989 28.0917194474799 1.27421035105457 0.203513463196346 -108.038042848871 73.5778659716164 -1.46834977370162 0.142991507872157 LARGE1 other 1 1 1 1.27421035105457 -1.46834977370162 0.0446122255715737 17.801400535877 7.76976803662642 2.29111093818525 0.0226086488697031 33.5791519798994 23.2666502844624 1.4432310439773 0.149936648071268 GSTT2B other 1 1 1 2.29111093818525 1.4432310439773 0.107000521848596 47.8767154620313 41.4719931112321 1.15443488171936 0.2491860134479 246.645745654163 124.166521125793 1.98641101818651 0.0478431007710444 MYO18B other 1 1 1 1.15443488171936 1.98641101818651 0.00099363535395669 21.8942129874374 5.82674540990214 3.75753726089177 0.000204095342941951 15.5296384562997 17.674565190493 0.878643309689619 0.380258114751274 SLC2A11 other 1 1 1 3.75753726089177 0.878643309689619 0.00224645200611124 261.739124182255 75.00963264849 3.48940682603815 0.000551948748417338 62.9197995052998 193.87828730139 0.32453247024763 0.745746985530398 C1QTNF6 other 1 1 1 3.48940682603815 0.32453247024763 0.00083894262958037 205.270748207279 65.2969834124936 3.1436482587648 0.00182538369295796 -256.537992152619 184.761830202657 -1.38847938381663 0.16595987706431 FAM83F other 1 1 1 3.1436482587648 -1.38847938381663 0.837034491380128 2.48119562382041 4.33930347562106 0.571795828007924 0.567865525551321 -0.366205827745459 12.1079353008874 -0.0302451093968613 0.97589060566105 SEC14L4 other 1 1 1 0.571795828007924 -0.0302451093968613 0.00471823019877256 -45.4337616083776 18.5604133272965 -2.4478852279415 0.014906582200759 -129.971812235726 41.2963862857645 -3.14729263079684 0.00180296801399408 GIMAP6 other 1 1 1 -2.4478852279415 -3.14729263079684 0.00224378976850245 -75.5158101325703 24.8783659856085 -3.03540072431823 0.00259928217066216 -170.611542125973 55.3536493925679 -3.08220946582937 0.00223332647868876 GIMAP4 other 1 1 1 -3.03540072431823 -3.08220946582937 2.84532680427734e-14 118.318491515532 28.9349384240178 4.08912193907835 5.48292087853677e-05 -288.659728233991 63.672419050978 -4.53351282292073 8.208225636103e-06 ADCK2 other 3.8616775387652e-10 0.121046703455611 0.582560343344532 4.08912193907835 -4.53351282292073 6.46806247418318e-20 309.016877988889 64.247886675942 4.80975941741912 2.33067561403334e-06 -800.794591767909 141.379888342001 -5.6641337120791 3.2928388353943e-08 MKRN1 other 9.37998420006045e-16 0.00049906265389236 0.0272152991450673 4.80975941741912 -5.6641337120791 7.62506951639615e-13 401.300851144028 78.176965348654 5.13323648921782 4.95294006603847e-07 -424.434084406226 173.700924431903 -2.44347625549119 0.015086499718152 AGAP3 other 1.00719543242077e-08 1 0.0059871139518273 5.13323648921782 -2.44347625549119 2.03194740561893e-13 124.275475889272 21.774915755158 5.70727700105267 2.65710772772117e-08 -92.9999151441785 48.7607520232957 -1.90726991043426 0.0573979196370581 KRBA1 other 2.71549451286914e-09 1 0.000338515524511677 5.70727700105267 -1.90726991043426 0.00481821053535469 -0.309299721091752 8.92345710760888 -0.0346614229621855 0.972371675922018 -56.8713719073851 20.0452869708868 -2.83714431177679 0.00484693613571011 ZNF767P other 1 1 1 -0.0346614229621855 -2.83714431177679 1.65806665815335e-07 31.1783534434095 6.72957120547271 4.63303715666969 5.26285087786616e-06 -7.28058456424238 15.018375261013 -0.484778442255497 0.628167269929993 ACTR3B other 0.00180712685072134 1 0.0601964883410332 4.63303715666969 -0.484778442255497 0.63065884212339 486.525174773785 1230.01790158986 0.395543165790456 0.692705635207422 -2335.90680876775 2936.83192695059 -0.795383211184711 0.426980193786533 NTS other 1 1 1 0.395543165790456 -0.795383211184711 0.523785122719163 -29.843268308596 255.140149679049 -0.116968138280616 0.906958678490354 -705.260451774666 620.943261403942 -1.13578888058159 0.256894856731001 BTG1 other 1 1 1 -0.116968138280616 -1.13578888058159 0.757731484326998 -2.29866843412356 5.89053413155004 -0.390230899743328 0.696625441617287 -9.73445759826503 14.0644365272797 -0.692132783235491 0.48935585145717 LRRIQ1 other 1 1 1 -0.390230899743328 -0.692132783235491 0.116184316402559 33.9789960092419 20.1537884008721 1.68598554938542 0.0927732986628837 -44.880512003163 48.7514043349499 -0.920599367657357 0.357953111132327 C12orf29 other 1 1 1 1.68598554938542 -0.920599367657357 5.73447840336525e-17 785.458425637992 85.5991475028202 9.1760075719459 5.66793881084508e-18 119.643834648298 534.915937786134 0.223668479842777 0.823157997565685 ATP13A3 other 8.07815972682063e-13 1 8.32393493760708e-14 9.1760075719459 0.223668479842777 0.060203008644455 12.0031732326543 5.56507426929161 2.15687565912435 0.0317620882515252 -1.58489278552767 13.0030559570312 -0.121886177431287 0.90306590775534 SFTPD other 1 1 1 2.15687565912435 -0.121886177431287 3.6188754748981e-07 173.123067379903 37.7463006602149 4.58649097664761 6.48433634399358e-06 -106.605267994003 88.1959945016467 -1.20873140097097 0.227661234744303 TMEM254 other 0.00387038732040351 1 0.073752841576583 4.58649097664761 -1.20873140097097 2.69656413130805e-08 243.56488621819 42.3627138345327 5.74951093004916 2.09959084668603e-08 -242.102322221804 230.981705692324 -1.04814500999613 0.295367766835735 TMTC1 other 0.000306707204294978 1 0.000268516673382676 5.74951093004916 -1.04814500999613 1.63193211411878e-20 378.409072723151 38.8845163013849 9.73161321566121 1.00003788658419e-19 -290.934017310589 186.909954854719 -1.55654639977162 0.120588730987171 KRAS essential 2.3767459310026e-16 1 1.48255616686107e-15 9.73161321566121 -1.55654639977162 1.06647577771449e-22 241.420387722132 23.7317731614175 10.1728760881057 3.19498475128206e-21 -308.149082097224 132.510765175338 -2.32546451369051 0.0206778980328433 IPO8 other 1.5744381906399e-18 1 4.76691724891283e-17 10.1728760881057 -2.32546451369051 4.13709832267563e-10 335.629488199533 90.6905258781409 3.70082194308269 0.000252939264001645 -537.431764529069 131.939343935118 -4.07332451791905 5.84879615059817e-05 LARS essential 5.07663335175527e-06 0.841641766071076 1 3.70082194308269 -4.07332451791905 0.513118221123053 716.017529029208 1047.75575896691 0.683382098262291 0.494859926025763 -973.645397183184 1518.92877275194 -0.641007935756703 0.521976324499997 SPINK5 other 1 1 1 0.683382098262291 -0.641007935756703 6.72172443868443e-07 60.2535081979563 11.0958827160357 5.43025820837836 1.11943584129821e-07 1.10226191092648 53.6669437134347 0.0205389357890814 0.98362633339345 IMPA1 other 0.00703966200463421 1 0.00139101097639716 5.43025820837836 0.0205389357890814 0.406588877748302 14.3935583347609 17.6094439544668 0.817377219404471 0.414324858407585 -84.4411718348468 86.6613484806944 -0.97438100508738 0.330608003778704 LRRCC1 other 1 1 1 0.817377219404471 -0.97438100508738 3.2593356204411e-06 83.418473286179 18.0971738009985 4.60947517018245 5.8538112490323e-06 -155.890438826207 89.0616131514025 -1.75036621626421 0.0810195236661631 E2F5 other 0.0324075740740459 1 0.0667393020502172 4.60947517018245 -1.75036621626421 0.0386754735127784 47.054379404869 20.4349359501514 2.30264384090327 0.0219442357776336 -32.9443354501765 48.0971113819853 -0.684954553476901 0.493871543679579 CCDC59 essential 1 1 1 2.30264384090327 -0.684954553476901 1.09241147527711e-16 377.557231620949 79.8328425909368 4.72934721309563 3.39541735173746e-06 -727.568118275084 161.490354525076 -4.5053348258153 9.33051310259591e-06 SWAP70 other 1.53396419358412e-12 0.13744778851434 0.0392835948068497 4.72934721309563 -4.5053348258153 3.13052403783349e-08 50.5212357204932 18.1934216824133 2.77689577048224 0.00581567418493228 -135.134421311633 38.0828668468799 -3.54843089557751 0.000446329666544661 ARNTL other 0.000354782289207669 1 1 2.77689577048224 -3.54843089557751 0.365014679566178 -1.31125071877257 13.1070028330303 -0.100041995525335 0.920374624929981 32.6028913486016 27.1288198783504 1.20178067069625 0.230351236464955 LYVE1 other 1 1 1 -0.100041995525335 1.20178067069625 6.76771947886996e-07 29.9469385559581 44.0798988299993 0.67937856825518 0.497395349628448 -403.455971762582 91.1155917392186 -4.42795754339511 1.31222363094206e-05 AMPD3 other 0.00708512552242896 0.192634429022294 1 0.67937856825518 -4.42795754339511 1.87458200750298e-09 67.3821783860805 16.5759540931962 4.06505580355933 6.06658024933526e-05 -92.6579037957916 34.6278355578337 -2.67582141081382 0.00784318510768227 MICALCL other 2.24143770637131e-05 1 0.64220818519463 4.06505580355933 -2.67582141081382 4.24080217427243e-11 149.002438422429 37.5215817099346 3.97111293373267 8.86315759949139e-05 -250.816725076921 75.9283936872769 -3.3033324280499 0.00106505326033127 SBF2 other 5.37182411415089e-07 1 0.924161442898967 3.97111293373267 -3.3033324280499 1.18261689432494e-07 719.706615945722 138.604979398186 5.19250187886931 3.7232419743671e-07 33.8772696968495 289.551383112683 0.11699916378457 0.906935040940969 MICAL2 other 0.00129957770517368 1 0.00452634526823809 5.19250187886931 0.11699916378457 4.68747074005005e-19 319.807212715033 40.2134418016203 7.95274411707149 3.27442548665224e-14 -141.384001326723 84.2374807955057 -1.67839778672805 0.0942580648712524 RRAS2 other 6.74808287737605e-15 1 4.68472054375336e-10 7.95274411707149 -1.67839778672805 4.32328665247161e-10 201.259953605897 84.5003678383228 2.38176423078978 0.0178141025985858 -623.053102249969 126.182913819628 -4.93769784981025 1.27521887619471e-06 HSD17B4 other 5.30251107925643e-06 0.0190785496067491 1 2.38176423078978 -4.93769784981025 0.0272298406340106 39.2988525864283 16.2707681347585 2.41530407544042 0.0162892917719757 -82.3696196868486 87.2584634765651 -0.943972841201479 0.345904695451503 ZFC3H1 essential 1 1 1 2.41530407544042 -0.943972841201479 0.00082139927365868 13.5061111547658 11.0114552054372 1.22655097830274 0.220898801136383 -47.6528754083269 22.1899024824443 -2.14750269614875 0.032508811039892 TEX15 other 1 1 1 1.22655097830274 -2.14750269614875 8.27058142984179e-23 645.459152588047 117.493390067014 5.49357842360238 8.06207327587237e-08 -937.361517979072 225.107391973776 -4.16406369315616 4.02776275661685e-05 SARAF other 1.22139946555903e-18 0.582817270882458 0.00100711419362198 5.49357842360238 -4.16406369315616 9.81567316253873e-09 41.4175642412552 11.0037268143043 3.76395787901735 0.000199682205378616 -49.2465915079856 24.6857094998471 -1.99494332979535 0.0469158436970198 RNF122 other 0.000113999228109725 1 1 3.76395787901735 -1.99494332979535 0.0536210372421197 59.8916269849319 27.4636352559169 2.18076108376907 0.0299525682812015 20.8635398522477 63.621902637657 0.327930146494846 0.743185847756516 DUSP26 other 1 1 1 2.18076108376907 0.327930146494846 6.66633907271057e-13 216.821266043164 30.8539732823419 7.02733693515102 1.3146366859404e-11 -258.556976154415 136.533786909412 -1.8937215615792 0.059181002925881 DPF2 other 8.81490015584519e-09 1 1.81498740860932e-07 7.02733693515102 -1.8937215615792 8.83495580436746e-18 247.950068723866 29.8869015091273 8.29627884470204 3.11719015792034e-15 -275.580305288833 121.95970391818 -2.25960129809527 0.024524627899457 MEN1 ts 1.2570375118454e-13 1 4.49935227394222e-11 8.29627884470204 -2.25960129809527 0.0216826615361234 4.14445383676153 1.54140307740038 2.68875409523073 0.00754874150027386 6.64036817882972 4.64470604181091 1.42966381920711 0.153792137818228 GSC other 1 1 1 2.68875409523073 1.42966381920711 0.0973794267118221 -1.99257565437384 2.47462411250325 -0.805203361717109 0.421302084778037 -15.7536306602201 7.29917943523468 -2.15827420054561 0.0316522925504999 CATSPERB other 1 1 1 -0.805203361717109 -2.15827420054561 3.51058159877927e-08 167.634541415969 30.8726515362211 5.42987184690932 1.12395294194736e-07 -115.289253481719 93.1670568587422 -1.2374465542742 0.216837157207197 COX16 other 0.000396730826478045 1 0.00139651153036959 5.42987184690932 -1.2374465542742 0.624648197360395 -51.7246325935058 71.1484838845429 -0.726995569961022 0.467763507856615 -173.657413529238 217.317101475392 -0.799096860533556 0.42483068816168 TTC9 other 1 1 1 -0.726995569961022 -0.799096860533556 1.34444692557081e-18 106.349153834132 12.5787889231825 8.45464173726072 1.0365821877469e-15 -98.0326170293848 37.9413570470226 -2.58379311282641 0.0102192838533643 MED6 other 1.92793689126855e-14 1 1.50148929895138e-11 8.45464173726072 -2.58379311282641 9.9784175814663e-28 760.330262542586 66.4910726654241 11.4350728911908 1.42559665178523e-25 -356.232380935601 210.515105859815 -1.69219391397414 0.091594730192624 EIF2S1 essential 1.50045465172509e-23 1 2.15008487022249e-21 11.4350728911908 -1.69219391397414 0.0157248047342059 537.034696583413 194.440701121995 2.76194589653568 0.00607778927184899 872.96357720236 359.560905130286 2.42786010588677 0.0157393012385432 LOXL2 other 1 1 1 2.76194589653568 2.42786010588677 1.55309031067011e-41 157.974591271648 19.7323418425554 8.00587140300574 2.21483070965081e-14 -212.972114297046 36.2036458961502 -5.88261510754895 1.01725246501642e-08 ELP3 essential 2.37358792179712e-37 0.000154612202157845 3.17363092385864e-10 8.00587140300574 -5.88261510754895 0.828086021205347 9.25880652988267 16.0287067772657 0.577639023443545 0.563915339138736 5.93411024292868 29.6305591603315 0.200269937898205 0.841397086365424 PEBP4 other 1 1 1 0.577639023443545 0.200269937898205 0.541525899100784 -12.2524794039054 25.0073297553308 -0.489955525991079 0.624502153436481 -50.2641849904999 46.4790757954825 -1.08143684292847 0.280319685900195 ADAMDEC1 other 1 1 1 -0.489955525991079 -1.08143684292847 6.54155186565548e-12 179.406246856453 34.2783137628562 5.23381191086642 3.02736600831789e-07 -67.9383888753169 55.2358817926424 -1.22996839500744 0.219620957592143 CTIF other 8.45430163117314e-08 1 0.00369520294975282 5.23381191086642 -1.22996839500744 2.70823221163968e-26 457.092621146728 94.15237847858 4.85481756842412 1.88994664391677e-06 -832.072938663922 146.40436317476 -5.68338894156244 2.98015030027358e-08 MBD2 other 4.05422362082461e-22 0.000451850388527481 0.0221766339197193 4.85481756842412 -5.68338894156244 1.34805694155372e-21 158.4827821615 34.0365298701902 4.65625558086937 4.75924263855701e-06 -273.460759695398 54.9320616502682 -4.97816305232489 1.06050792107735e-06 IER3IP1 other 1.977329921871e-17 0.0158842876418965 0.0545456798805018 4.65625558086937 -4.97816305232489 6.19120282425261e-09 45.7265061286707 14.3512888731998 3.18622992908061 0.00158399753776691 -74.6321783881282 19.5873442932123 -3.81022446284313 0.000166569415678501 MRPS36 other 7.25670883030649e-05 1 1 3.18622992908061 -3.81022446284313 1.09972656441371e-07 535.801519702535 136.543393513287 3.92403840212449 0.000106686650454769 -451.311888107013 186.361133368505 -2.42170607116132 0.0160050903610128 CCNB1 other 0.00121068897476305 1 1 3.92403840212449 -2.42170607116132 1.02956057900929e-09 109.416746124717 23.0803917187362 4.7406797708678 3.21481263518857e-06 -77.3683902252973 31.5012528150925 -2.45604169076823 0.0145804175444862 CDK7 essential 1.24288553098002e-05 1 0.0372564636292003 4.7406797708678 -2.45604169076823 0.00528847779036783 -10.6908206051413 10.0674881673709 -1.06191538816908 0.289079889637864 -46.0847803393566 14.1540944520539 -3.25593279707619 0.00125206688419967 CD180 other 1 1 1 -1.06191538816908 -3.25593279707619 2.20818838691627e-07 189.600471456668 48.8812796920056 3.8787951676248 0.000127443790128991 -140.988958144707 79.5323349777029 -1.77272499523915 0.0772255738337316 IRAK2 other 0.00239080556651425 1 1 3.8787951676248 -1.77272499523915 0.00478242094459833 13.6037947057499 10.6990780883746 1.27149223450677 0.204479848673097 -38.8667661823542 18.222823858797 -2.13286187055973 0.0336991582445848 CAMK1 other 1 1 1 1.27149223450677 -2.13286187055973 2.20068024636865e-33 259.784857434653 25.3991101534109 10.2281086174102 2.04329418973037e-21 -159.50879402215 43.2822210957893 -3.68531905211462 0.000268434763238591 THUMPD3 other 3.34063261398761e-29 1 3.05145554294334e-17 10.2281086174102 -3.68531905211462 1.16430945884971e-18 230.335688419351 38.6410042397551 5.96091361886434 6.62310499501739e-09 -243.119898114734 62.8708845683853 -3.86697117089692 0.000133489386522963 VHL ts 1.67020191871992e-14 1 8.61069880402212e-05 5.96091361886434 -3.86697117089692 5.885325954898e-07 2165.43450215869 584.051774653494 3.70760709261332 0.00024690517613768 -1847.05235628394 959.779290089425 -1.92445531525466 0.0551924038762887 BHLHE40 other 0.00619077437195721 1 1 3.70760709261332 -1.92445531525466 7.71251689274944e-22 869.54712567878 100.471044549715 8.65470374649596 2.533679084528e-16 -272.748488521261 165.105273192053 -1.65196715554927 0.0995313917935853 ARL8B other 1.13266023086918e-17 1 3.68599633217134e-12 8.65470374649596 -1.65196715554927 2.76981027411285e-14 516.741625364506 71.1681565998275 7.26085443339639 2.99372816827353e-12 -37.3451323558194 116.951485780314 -0.319321572587541 0.749693000108796 EDEM1 other 3.76029442813561e-10 1 4.17595142192474e-08 7.26085443339639 -0.319321572587541 0.370995355462456 -126.241562080054 89.5046071964598 -1.41044764101313 0.159419956172992 -94.578556194807 142.82494326397 -0.662199151166519 0.508340377635623 CHL1 other 1 1 1 -1.41044764101313 -0.662199151166519 0.144592562581517 31.98976702598 23.0599731375315 1.38724216351817 0.166336353196842 -37.0848442700311 46.7549733662054 -0.793174321361846 0.428265808350308 MEIS2 other 1 1 1 1.38724216351817 -0.793174321361846 2.38431317469696e-08 38.4136012820908 8.30256190599187 4.62671663482185 5.41548585434741e-06 -32.5458769590834 17.3458631399397 -1.87629042709007 0.0615311422987031 DPH6 other 0.000271954760705935 1 0.0618990033151909 4.62671663482185 -1.87629042709007 0.00034344792577987 63.3962307980687 20.9092313194656 3.03197328631826 0.00263005137394783 -57.0216358814777 43.6528225730123 -1.30625312455123 0.192413485295557 KATNBL1 other 1 1 1 3.03197328631826 -1.30625312455123 5.11674998797912e-07 105.127469312559 36.6856388479161 2.86563005617472 0.00443991917973992 -248.212897349738 76.5896966338895 -3.24081316754959 0.00131854041307209 EMC7 essential 0.00540533468730115 1 1 2.86563005617472 -3.24081316754959 0.363603595327031 -337.257422777634 500.192721637929 -0.674254958515293 0.500636015288256 783.677388863344 929.116163139274 0.843465456693245 0.399598224402597 GSTM1 other 1 1 1 -0.674254958515293 0.843465456693245 2.90803131467727e-05 103.506471050167 46.1543364248308 2.2426163838092 0.0256059264709446 -241.879650273614 88.1835331804258 -2.7429117608468 0.0064327560781325 PRPF38B essential 0.266201186545558 1 1 2.2426163838092 -2.7429117608468 0.135522980800039 20.4922142551369 11.8220514652511 1.73338902434744 0.0839928192328703 -1.8477973225405 21.5559647986485 -0.0857209287452703 0.931742040629437 TSPAN2 other 1 1 1 1.73338902434744 -0.0857209287452703 0.57633532351109 -48.6795377933456 108.855166461995 -0.447195474275822 0.655036463901396 134.733071410372 202.200252474419 0.666334832729337 0.505677201729748 GSTM5 other 1 1 1 -0.447195474275822 0.666334832729337 0.380515714523685 152.336478507771 322.423439807397 0.472473336922312 0.636911028606644 829.815027280795 598.906813995712 1.38554948430882 0.166849443987099 GSTM3 other 1 1 1 0.472473336922312 1.38554948430882 2.51471834539357e-06 151.66587882467 77.8979735465849 1.94698105636818 0.0524116318308406 -530.353625994756 149.042513119779 -3.55840501406827 0.000429605277777001 VAV3 other 0.0252251397226429 1 1 1.94698105636818 -3.55840501406827 0.000127354920365719 7.64297390255093 18.9478399799567 0.403369139207201 0.686946917495881 -129.734204107732 35.1590463146201 -3.68992386615971 0.000263688655376052 PSRC1 other 1 1 1 0.403369139207201 -3.68992386615971 0.131129149083214 14.4872263899268 9.91957834769214 1.46046796367079 0.145174232225784 34.986983265063 18.4533878981171 1.89596530773804 0.0588944069759862 HMGCS2 other 1 1 1 1.46046796367079 1.89596530773804 0.452090797027056 -12.5559513396597 11.5457609322732 -1.08749448505925 0.277639317345451 -22.6425328592182 21.0365052916891 -1.0763447894629 0.282586423785663 PTPN22 other 1 1 1 -1.08749448505925 -1.0763447894629 0.0375702440747801 131.107597188632 132.103790463388 0.992459010666829 0.321725865301284 -421.774666682383 245.127850570424 -1.7206313591087 0.0862874311782341 SORT1 other 1 1 1 0.992459010666829 -1.7206313591087 0.903256284979508 32.0970455780372 85.7696181018314 0.374223953520808 0.708486327183272 61.9635645613881 156.87061962995 0.394997895128847 0.69310842489648 WNT2B other 1 1 1 0.374223953520808 0.394997895128847 1.879771067996e-07 1696.57405010872 450.907376922756 3.76257771981263 0.000200304030229906 -1811.74373848224 833.797622726034 -2.17288187097354 0.0305295504884624 PTGFRN other 0.00204293519669806 1 1 3.76257771981263 -2.17288187097354 1.81266914533133e-08 -5.79975247524743 47.6291415043202 -0.121768990413597 0.903158403814496 -493.003410341033 88.3701235465863 -5.57884713243764 5.16069427363943e-08 LAMTOR5 other 0.000208075823397354 0.000781225899143537 1 -0.121768990413597 -5.57884713243764 0.000659074345543382 310.458768348636 204.79384545969 1.51595751157348 0.130552390482645 -974.165873284818 383.021099965035 -2.54337391170812 0.0114659150167968 NOTCH2 og 1 1 1 1.51595751157348 -2.54337391170812 0.455463290787862 -2.14442126389737 9.98839793064846 -0.214691212623539 0.830146555125832 -22.0712106407514 18.3301650295742 -1.20409230386858 0.229455043098446 TRIM45 other 1 1 1 -0.214691212623539 -1.20409230386858 6.43082706807313e-12 24.769882319101 23.1519314873823 1.06988405406264 0.28547783024676 -263.076920679015 42.8075377027625 -6.1455747000846 2.36723816945348e-09 CEPT1 other 8.31377323360494e-08 3.60861786551488e-05 1 1.06988405406264 -6.1455747000846 0.0317793079199821 1.60971632674186 6.72225801099014 0.23946065802743 0.810903152564699 -27.9762463332989 12.4304968953187 -2.25061367770701 0.0250951232417025 CD101 other 1 1 1 0.23946065802743 -2.25061367770701 0.286867020588334 -78.5331291097794 49.6017831396301 -1.5832722966573 0.114359685760099 -61.8940414256917 91.0264966437462 -0.679956317202108 0.497029939165728 VTCN1 other 1 1 1 -1.5832722966573 -0.679956317202108 0.014277949982186 17.8778092893835 7.03987014608431 2.53950838842211 0.0115752355675453 -1.53008250311334 12.8362825607803 -0.119199814733615 0.905192083323128 NGF other 1 1 1 2.53950838842211 -0.119199814733615 9.87807617902726e-15 5.69480687058595 12.4168995093794 0.458633563578751 0.646809639266421 -163.601923276762 22.6237295027729 -7.23143031111248 3.56553311378718e-12 AP4B1 other 1.35309887500315e-10 5.46346639025609e-08 1 0.458633563578751 -7.23143031111248 8.08965585485291e-43 279.211858057652 17.1103837921527 16.3182697389702 8.18224180914636e-44 142.300376388171 71.6738503499938 1.98538763709913 0.047968229691079 NAPG other 1.23715106988266e-38 1 1.25229210888985e-39 16.3182697389702 1.98538763709913 5.7866221586609e-39 455.894235389049 29.6129472057151 15.3950983744389 4.97549001552087e-40 264.255984916358 125.295289022821 2.10906560795137 0.0357484791109366 SPIRE1 other 8.83385738741172e-35 1 7.60503648872365e-36 15.3950983744389 2.10906560795137 4.76244722076376e-05 104.288506538197 27.4342151624279 3.80140295323716 0.000172632549941822 -122.064616571774 73.3632737266916 -1.66383819002564 0.0971360788513997 PPHLN1 other 0.426048528369526 1 1 3.80140295323716 -1.66383819002564 0.897778954846378 7.49985065933911 41.6621578984638 0.180015895422826 0.85725438740801 47.7159465957796 104.400434191553 0.45704739606955 0.647948060731225 FKBP11 other 1 1 1 0.180015895422826 0.45704739606955 7.7111223456464e-12 1037.73221726079 181.491123180829 5.71781252478585 2.48115459967822e-08 -1555.78615910754 454.79526308189 -3.42084952372823 0.000705487888999658 ARF3 other 9.94889005035299e-08 1 0.000316396834550967 5.71781252478585 -3.42084952372823 0.156114244678297 11.3338094282982 84.2780936141261 0.134481084493806 0.893107241740451 -408.531736999054 218.711725937902 -1.86790047605882 0.0626955348559746 TMEM106C other 1 1 1 0.134481084493806 -1.86790047605882 0.000207196858723776 2603.07676609391 670.794642273467 3.88058669829491 0.000126853048995339 -1482.20007740887 1827.39568712684 -0.811099691134374 0.417918902310995 SLC38A2 other 1 1 1 3.88058669829491 -0.811099691134374 0.824580991078598 1.95483170466884 3.319856996344 0.588830093230402 0.556395923798292 -0.704528738047694 8.86284690768291 -0.079492373656704 0.936691313664029 PLEKHA8P1 other 1 1 1 0.588830093230402 -0.079492373656704 1.51470049676894e-07 1147.53507625291 292.893443484113 3.91792681530326 0.000109299113064096 -2731.90130250635 881.684898619258 -3.09850073057231 0.0021180735368371 YWHAQ other 0.00165481029272007 1 1 3.91792681530326 -3.09850073057231 4.55949004068604e-06 343.028802769663 72.911110963043 4.70475347637395 3.79201626112586e-06 -136.601231517859 219.464763289885 -0.622428992564176 0.534104474598706 KIDINS220 other 0.0448289060800252 1 0.0437409075720868 4.70475347637395 -0.622428992564176 0.0191064732659063 325.263633896139 124.592208055762 2.61062580856233 0.00946431470985483 -155.000069521402 375.054719633395 -0.413273214300328 0.679684118677372 GRHL1 other 1 1 1 2.61062580856233 -0.413273214300328 2.35624520330426e-08 255.030551896372 42.9448790678447 5.93855559573174 7.51076179927345e-09 10.706958566606 130.542500741633 0.0820189478964936 0.934683083840336 ROCK2 other 0.000268776890340917 1 9.74446235837738e-05 5.93855559573174 0.0820189478964936 0.475488064861023 -192.805533081418 157.984997383049 -1.22040406541859 0.223213106567145 -158.531800740743 475.53986760123 -0.333372260753713 0.739072310981749 RSAD2 other 1 1 1 -1.22040406541859 -0.333372260753713 0.667012569866832 -0.823644162509343 9.85410161283393 -0.083583891750886 0.933440031275091 -28.1630782437347 31.4711477068636 -0.894885642749933 0.371527186679538 MYCN og 1 1 1 -0.083583891750886 -0.894885642749933 0.00553807479597027 122.884890087272 39.203700692811 3.13452270871474 0.00188134788032324 188.124916381937 119.170183683158 1.57862403637903 0.115413382793071 LPIN1 other 1 1 1 3.13452270871474 1.57862403637903 0.143395801479254 -55.7752914814588 51.4726896005194 -1.08358999528356 0.279367520245281 -293.642226409177 157.012213351683 -1.87018716659616 0.0623763779312263 CMPK2 other 1 1 1 -1.08358999528356 -1.87018716659616 1.07002633311178e-09 226.970835190747 39.8546172958745 5.6949696318936 2.80224095379718e-08 -226.67124305813 119.963665829774 -1.8894991370118 0.0597316174492201 IAH1 other 1.29120077616599e-05 1 0.00035661318378023 5.6949696318936 -1.8894991370118 7.18307311965615e-17 8227.32431234109 1211.933466128 6.78859404603006 5.53327875363416e-11 -6170.54761745414 2535.63592070283 -2.43353060550735 0.0155011517172336 LDHA other 1.01051472647323e-12 1 7.54905220358309e-07 6.78859404603006 -2.43353060550735 0.129040559397748 236.999728951948 230.053663302456 1.0301932407847 0.303699749675528 -529.724851648598 481.32372664208 -1.10055836088569 0.271918694244313 SAA2 other 1 1 1 1.0301932407847 -1.10055836088569 0.0976495977906408 5.07653376408838 4.15875165425355 1.22068692389846 0.223114649265709 -9.24656742064055 8.83483917669033 -1.04660280008679 0.296082690642057 ANO3 other 1 1 1 1.22068692389846 -1.04660280008679 4.41837836397308e-05 205.081736007599 142.393514465313 1.44024632566785 0.150784599263452 -816.99645830371 238.540960715041 -3.42497345468347 0.000695769303684098 IL6ST og 0.396637825733864 1 1 1.44024632566785 -3.42497345468347 0.00229310736012528 1121.19137009154 351.056931970621 3.19375938198358 0.0015477521830788 -33.0497038485065 524.551139406606 -0.0630056849860125 0.949802322251683 FST other 1 1 1 3.19375938198358 -0.0630056849860125 0.000826659601013054 565.438151783019 174.245585049795 3.24506443948884 0.0012992356043829 -1130.37980622393 592.19193085351 -1.90880649892467 0.057187079865406 NAV1 other 1 1 1 3.24506443948884 -1.90880649892467 7.05920255103284e-05 136.830203802622 31.0745305429057 4.40329110084851 1.46098390275742e-05 -58.1056216615131 106.353648736478 -0.54634347153887 0.585215389786674 CDC73 ts 0.618880287649049 1 0.162037724654825 4.40329110084851 -0.54634347153887 0.00210291877982574 121.797976983175 34.5349281094511 3.52680557484186 0.000482085422151942 -31.5535854040408 117.458452946366 -0.268636139950258 0.788382802129444 TIMM17A other 1 1 1 3.52680557484186 -0.268636139950258 0.494049315527536 -10.6553384200602 14.2390309582322 -0.748319071102231 0.454820803827314 -49.4402192109112 45.4293842318031 -1.08828724066879 0.277292424286636 ERN2 other 1 1 1 -0.748319071102231 -1.08828724066879 0.00399034407338879 1009.55592636285 425.965715863349 2.3700403313367 0.0183787743477762 -2096.71672047683 1303.12212917248 -1.60899479299635 0.108603544615074 RPS15A essential 1 1 1 2.3700403313367 -1.60899479299635 5.29949941039045e-22 681.630948926291 128.649490943087 5.29835714023802 2.17937642309988e-07 -800.473979493133 195.208884725372 -4.10060218631583 5.23081484568634e-05 NARS essential 7.78973418333293e-18 0.754178884451056 0.00267692806049358 5.29835714023802 -4.10060218631583 0.0842613145655777 15.6099551697745 7.87375521651803 1.98252990352392 0.0482749029495292 4.82569772820938 11.9269001763441 0.404606197491339 0.686037312819712 GRP other 1 1 1 1.98252990352392 0.404606197491339 8.96008165186314e-10 146.024448836758 57.6061353648133 2.53487667436812 0.0117262680899309 -311.42589614827 93.6605720948282 -3.32504798105399 0.000987053208694118 KIAA1468 other 1.08569309375626e-05 1 1 2.53487667436812 -3.32504798105399 4.34439443099234e-25 369.655444405445 49.8978558420158 7.40824306310537 1.15413904235551e-12 -434.66044724378 102.261189067379 -4.25049279406859 2.80408116991044e-05 FBXO18 other 6.47879541493888e-21 0.407881646975172 1.61902624861631e-08 7.40824306310537 -4.25049279406859 1.17454389110468e-21 407.534346846848 56.95413062181 7.15548358648437 5.75513983750797e-12 -398.9629004004 116.722392603911 -3.41804936910652 0.000712524586964252 RBM17 essential 1.72352570580701e-17 1 7.98986063641231e-08 7.15548358648437 -3.41804936910652 0.136276339052558 -28.5740074490075 17.4034779392975 -1.64185615936494 0.101605245038862 -64.0512877596211 35.666870208116 -1.79582024960088 0.0734693370391629 IL2RA other 1 1 1 -1.64185615936494 -1.79582024960088 3.69392589656413e-14 57.9623552123553 8.5163561166719 6.8060041663695 4.97922034463165e-11 -14.4520592020592 17.4535095409609 -0.828031701483435 0.408271590354704 ANKRD16 other 5.00046748617887e-10 1 6.79862745856005e-07 6.8060041663695 -0.828031701483435 0.0636499411941537 44.941842877594 28.3845520093657 1.58332049287814 0.11434241544332 -39.0175808558921 56.2120774392464 -0.694113838757551 0.488117570325827 ECHDC3 other 1 1 1 1.58332049287814 -0.694113838757551 0.00232754953536323 -32.9006108381108 30.32442981981 -1.08495398045763 0.278761290151642 -214.606035960203 62.1472045007771 -3.45318888732186 0.00062878696992457 IL15RA other 1 1 1 -1.08495398045763 -3.45318888732186 1.15004055388392e-12 83.5764658331869 18.1969295178172 4.59288836346562 6.29371369107121e-06 -98.1067190985282 25.3744910804446 -3.86635218761634 0.000133813234334547 CCNH essential 1.5128783486343e-08 1 0.0716413429454635 4.59288836346562 -3.86635218761634 2.0489409907196e-12 115.108236181274 16.5166464203473 6.96922566795819 2.42277764514671e-11 4.06684383134143 36.4780716846249 0.111487357843412 0.911312417670211 TMEM241 other 2.6796050276631e-08 1 3.32792737337352e-07 6.96922566795819 0.111487357843412 9.13571148183086e-11 277.234423256624 60.3534474428255 4.59351428962291 6.43968207071001e-06 -261.725395555837 121.093157936541 -2.16135576952245 0.0314640857117921 KCTD1 other 1.1436997204104e-06 1 0.0732578232363971 4.59351428962291 -2.16135576952245 0.00155728251810325 69.1546719642138 22.5469083754981 3.06714653789806 0.00238230133703409 -22.1433079916203 50.3741893230789 -0.439576463446437 0.660598136874256 CABLES1 other 1 1 1 3.06714653789806 -0.439576463446437 0.0021330865081827 -49.2089171149922 42.4724948660615 -1.15860669994014 0.247483146857158 -221.634274309985 62.6174647454871 -3.53949613276156 0.000460520196407293 DOCK2 other 1 1 1 -1.15860669994014 -3.53949613276156 0.430921866271635 1015.61820417811 781.818325003966 1.2990463023145 0.194863249101534 931.601937798052 3024.14576801287 0.308054574502273 0.758241225808863 EMP1 other 1 1 1 1.2990463023145 0.308054574502273 0.129297916468152 10.5986967146348 5.22398712778368 2.02885199664176 0.0433222498198203 7.34105828049386 22.4275576742951 0.327323125732396 0.74364301083045 SOX5 other 1 1 1 2.02885199664176 0.327323125732396 0.0112011646055397 27.9204337938026 9.52512798226747 2.93123975297559 0.00361919880855651 -3.66179610079309 37.3231138748711 -0.0981106805040322 0.921905831624914 RERG other 1 1 1 2.93123975297559 -0.0981106805040322 0.319153244589846 -6.64281352431409 4.39448714686457 -1.51162429250787 0.131616349549774 -8.26190926541243 23.0249884226656 -0.358823601287004 0.719963681987244 KLRD1 other 1 1 1 -1.51162429250787 -0.358823601287004 0.0353922749367191 -4.08493107628752 1.60091214048311 -2.55162727109734 0.0111867634885309 0.169154954874059 8.38800576004151 0.0201662897848584 0.983923287494785 KLRC1 other 1 1 1 -2.55162727109734 0.0201662897848584 0.840682812380018 44.3944771227152 282.82080535428 0.156970336984593 0.875367216784448 -785.430128305871 1481.84430886718 -0.530035526408509 0.596454870733958 PRH2 other 1 1 1 0.156970336984593 -0.530035526408509 2.10250826579811e-06 288.943976414436 61.634665228179 4.68801080276385 4.10866218426734e-06 18.9996725276864 154.498303125072 0.122976577369303 0.902203822153848 LRP4 other 0.021193283319245 1 0.0472948104031014 4.68801080276385 0.122976577369303 1.45587998675942e-05 16.4581112203017 52.2571449557741 0.314944707259275 0.753010191316234 -540.657998694703 131.938402406331 -4.09780616434657 5.29884126714798e-05 DDB2 ts 0.137041983153665 0.763827968659382 1 0.314944707259275 -4.09780616434657 2.6312489766891e-06 113.082854849478 39.4814767692428 2.86420023015888 0.00445860438817124 -247.574422181047 99.6825022489294 -2.48362969022185 0.013519947678161 ACP2 other 0.0263572209994947 1 1 2.86420023015888 -2.48362969022185 1.84168454988427e-06 33.3855653158241 6.49425743936676 5.14078254943331 4.8210483196503e-07 33.3872705245748 15.3227731859976 2.17893132785423 0.0300799372596328 PIWIL4 other 0.018650739436678 1 0.00583057583778507 5.14078254943331 2.17893132785423 0.110437991948258 176.00523981389 85.5572452508247 2.05716347339027 0.0404882913224896 4.99509228398964 175.498647463643 0.0284622836482227 0.977311359067695 PUM1 other 1 1 1 2.05716347339027 0.0284622836482227 0.00492752638814718 61.3794406651547 19.5831350669891 3.1343010429735 0.00188324279623923 -10.379440665155 41.8801238630171 -0.247836914215069 0.804420544545025 SPOCD1 other 1 1 1 3.1343010429735 -0.247836914215069 9.55141738108139e-08 362.302560878014 87.6435758959684 4.13381764920296 4.57234965264697e-05 -606.83645780884 196.95360503526 -3.08111373589836 0.00224305450472507 YARS essential 0.00105581367730474 1 0.489674841209656 4.13381764920296 -3.08111373589836 0.0164655495596549 96.7675650039932 46.0210666662542 2.10267975111819 0.0362795011358911 -168.985677757371 109.309843911685 -1.54593284291851 0.123115354049314 CDCA8 essential 1 1 1 2.10267975111819 -1.54593284291851 3.35485381207936e-08 294.888166063029 53.2297333801181 5.5399143925296 6.35224300000854e-08 -164.387274586084 126.431964070661 -1.30020343980586 0.194472814414424 GNL2 essential 0.000379501063222417 1 0.000797015929211072 5.5399143925296 -1.30020343980586 0.886807546859985 -12.3651415070302 25.2917816763628 -0.488899582688807 0.625249798240901 -7.6556661492499 60.370380776123 -0.126811626013096 0.899169638562925 AGO4 other 1 1 1 -0.488899582688807 -0.126811626013096 0.0123923244417221 17.5420921025214 49.5019304395023 0.354371878970661 0.723294341534301 -327.083989418085 117.523263979362 -2.78314248892477 0.00570444803437628 HOOK1 other 1 1 1 0.354371878970661 -2.78314248892477 0.0704139756474897 -1.71098145446963 11.0466810128087 -0.154886472460438 0.877008770840814 -59.6564456363191 26.2260885027654 -2.27469855560156 0.0235875102928487 CYP2J2 other 1 1 1 -0.154886472460438 -2.27469855560156 2.75026121056689e-05 97.2065234985042 31.0620133166266 3.12943409390892 0.00191323828806671 -199.414970498914 75.5915798516138 -2.63805798066881 0.00874704140498618 BTF3L4 other 0.252336466069512 1 1 3.12943409390892 -2.63805798066881 0.178917731462398 57.2668368089706 30.8925045840228 1.85374535279953 0.0646986088157863 20.5871572243475 75.1581884729487 0.273917688047489 0.784325157013924 ZCCHC11 other 1 1 1 1.85374535279953 0.273917688047489 1.23286474870773e-07 68.3245663366542 30.1291284013666 2.26772462271279 0.0240145075489216 -341.628095576274 73.3009751526174 -4.66062142918265 4.63841855476693e-06 PRPF38A essential 0.00135319234818161 0.068820216097077 1 2.26772462271279 -4.66062142918265 0.000212488274390274 3459.69987225431 1399.07259527221 2.47285229082854 0.0139264246533463 -3490.94198503858 2521.15586299061 -1.38465932879596 0.167127408541814 DSC2 other 1 1 1 2.47285229082854 -1.38465932879596 5.31330520337014e-05 5606.2340408764 1861.65548811561 3.01142401301709 0.00280936214233985 -3490.88884504558 3335.47949626465 -1.04659280590841 0.296084773562101 DSG3 other 0.472459098683673 1 1 3.01142401301709 -1.04659280590841 1.69223678634626e-13 180.420586847075 31.6141341366931 5.70695961708053 2.63538027319568e-08 -80.3187146003774 55.9312953056769 -1.43602457553357 0.151978312329058 RNF138 other 2.26505893852447e-09 1 0.000335831974272484 5.70695961708053 -1.43602457553357 1.73154685931302e-31 409.953988716996 43.3951663626972 9.44699659152351 8.30633080598734e-19 -202.664758530517 77.6500636395248 -2.60997543377876 0.00948880873012052 ELP2 essential 2.62208140905771e-27 1 1.22593136365567e-14 9.44699659152351 -2.60997543377876 0.147621043242079 1782.08579366249 1389.75237894696 1.28230454623349 0.200669813235334 -1291.10901981054 2527.95393503851 -0.510732811193756 0.609892528988464 DSG1 other 1 1 1 1.28230454623349 -0.510732811193756 4.10422389357318e-10 5942.56667542601 1097.86656994166 5.41283142972628 1.22392813589507e-07 -1015.58914483143 2062.10664498614 -0.492500786659485 0.622705222150436 DSC3 other 5.03756353076294e-06 1 0.00151852763820501 5.41283142972628 -0.492500786659485 0.86761711449312 -108.416585008263 233.019640610949 -0.465268012275737 0.642057992962444 -201.770998676009 423.016890476991 -0.476980950922535 0.633703304776625 DSC1 other 1 1 1 -0.465268012275737 -0.476980950922535 0.00142788165193564 93.7249607142769 29.1744613365409 3.21256867892491 0.00145159547093297 16.2209316293586 52.6335702647206 0.308186040729812 0.758144467470689 DTNA other 1 1 1 3.21256867892491 0.308186040729812 2.90905842324864e-07 246.223814025941 62.2307980214788 3.95662311675575 9.40314825101659e-05 -123.911472725645 111.354001648904 -1.11277072122055 0.266658081170477 FHOD3 other 0.00312694689914997 1 0.977175166245644 3.95662311675575 -1.11277072122055 3.36469649652933e-23 664.192622681823 97.6464571791855 6.80201455197704 5.22111996017689e-11 -607.446395684857 172.478216645026 -3.52187312404228 0.000492043076065135 TPGS2 other 4.97941434521376e-19 1 7.12578452164942e-07 6.80201455197704 -3.52187312404228 0.982305314020586 -0.472439660795753 9.09073964505284 -0.0519693313461962 0.958585760131569 5.18042224500158 32.6578008527554 0.158627406308178 0.874063124878459 DAGLA other 1 1 1 -0.0519693313461962 0.158627406308178 0.0113888734154418 125.679145319024 72.0549244503946 1.74421313015942 0.0820942640127871 -543.914543392919 276.076879678001 -1.97015608126007 0.0496933337308352 SLC43A3 other 1 1 1 1.74421313015942 -1.97015608126007 0.332454498652483 44.5841214032344 29.9898416497898 1.48664077402846 0.138113108760308 39.2883438670835 114.534533410015 0.343026183434455 0.731808297203217 TIMM10 essential 1 1 1 1.48664077402846 0.343026183434455 2.93068330872546e-06 122.710001722039 25.743213112256 4.76669331007553 2.84716605891909e-06 -42.7614334381175 58.3008682357397 -0.733461348555078 0.463814087340375 DHX34 other 0.02924821942108 1 0.033078375272522 4.76669331007553 -0.733461348555078 0.226491544590974 -16.2459689809649 18.3571563770014 -0.88499376740716 0.376832891767647 106.627628046513 80.8743103723957 1.31843631872139 0.188312424206712 APLNR other 1 1 1 -0.88499376740716 1.31843631872139 0.174253616660355 -262.182000097613 191.247436058119 -1.37090465368612 0.17137754955159 -1096.32376722469 674.416822575703 -1.62558781235269 0.105034227420323 FADS2 other 1 1 1 -1.37090465368612 -1.62558781235269 0.31121169272974 -117.662320937101 95.3693422858106 -1.23375414065959 0.218202755795079 -420.118198278587 340.083743090107 -1.23533749205787 0.217613945637818 TCN1 other 1 1 1 -1.23375414065959 -1.23533749205787 0.486716280384438 17.459930739872 18.259652453831 0.956202796521947 0.339691598341814 -19.573661022411 41.3527863479629 -0.473333546564636 0.63629796149227 C5AR2 other 1 1 1 0.956202796521947 -0.473333546564636 7.02880918525633e-10 274.751707319381 77.5883857481505 3.54114478178753 0.000459153907788801 -654.548968035253 165.176447505227 -3.9627257876129 9.18931732035793e-05 TMEM165 other 8.54914061202727e-06 1 1 3.54114478178753 -3.9627257876129 1.99983170064243e-08 96.6927644319773 39.4482633017675 2.45112855012923 0.0147892460565066 -359.917004453212 83.9806619200362 -4.28571287989983 2.42999111209852e-05 CLOCK other 0.000228980729723558 0.354025405121634 1 2.45112855012923 -4.28571287989983 0.564556273703393 76.7053325599999 82.1034763919138 0.934251945604028 0.350903430889389 -21.569963343092 174.822262105624 -0.12338224596396 0.901884629624169 PDGFRA other 1 1 1 0.934251945604028 -0.12338224596396 0.000573049871373176 14.7752595628067 4.86771753669748 3.03535680766535 0.00260219901343356 -19.0412519232782 11.2905781538717 -1.68647270881771 0.0926917371506939 GGACT other 1 1 1 3.03535680766535 -1.68647270881771 0.0760395852067685 1339.80353042349 589.537194601179 2.27263613338233 0.0237173055651804 497.334019533182 1441.98324754844 0.34489583729819 0.73040139877281 COL4A2 other 1 1 1 2.27263613338233 0.34489583729819 0.0480374527782711 -72.2483682196713 47.7077802884108 -1.51439383226182 0.130938348396591 -251.600945307224 111.151430555918 -2.26358710858561 0.0242861347045694 CLDN10 other 1 1 1 -1.51439383226182 -2.26358710858561 0.000810511591646787 59.2545089725759 20.7460345818962 2.85618481636407 0.00457437301708764 -85.645684354932 48.3010471921385 -1.77316413067068 0.0771739295774972 DZIP1 other 1 1 1 2.85618481636407 -1.77316413067068 2.45049117854765e-37 465.053371309019 33.4233677848877 13.9140189074331 1.22919534780082e-34 -149.894638241586 77.6843147184421 -1.9295354382009 0.0545623116769166 UBAC2 other 3.73577380169589e-33 1 1.87403122725712e-30 13.9140189074331 -1.9295354382009 0.00328220436092791 117.980472783943 43.1808021027528 2.73224366011537 0.00664314803740972 -136.920764565613 102.480472487485 -1.3360668744217 0.182485733891268 ARGLU1 other 1 1 1 2.73224366011537 -1.3360668744217 1.97519158293071e-08 59.3000790449111 10.052844721498 5.89883567166796 9.38761687320713e-09 -5.78089862540688 23.2783642893239 -0.248337836523083 0.804033824947581 BIVM other 0.00022633720348803 1 0.000121372498553695 5.89883567166796 -0.248337836523083 1.80982693088196e-26 209.385025469107 21.4892215261852 9.74372315972292 8.69020009758057e-20 -227.29425422669 49.8595342366429 -4.55869188725086 7.36804079416879e-06 ERCC5 other 2.71148270784735e-22 0.108803858407491 1.2887566744712e-15 9.74372315972292 -4.55869188725086 2.78577848938578e-20 217.109655608803 22.5707226598063 9.61908304315969 2.19119188926396e-19 -57.1188750554678 52.2647587726767 -1.09287551299919 0.275278286098539 TPP2 other 4.05024334571798e-16 1 3.24274487692173e-15 9.61908304315969 -1.09287551299919 5.71731627646362e-10 48.2900023349584 7.171115264961 6.7339598585048 7.76414052035359e-11 33.2275207695052 16.605432404771 2.00100304283304 0.0462443231868146 KDELC1 other 6.97855624705149e-06 1 1.05685480763053e-06 6.7339598585048 2.00100304283304 7.05656986974535e-16 184.390273018397 22.5460113050678 8.17839885394497 7.01562202567919e-15 -76.3580312539619 55.1530833194548 -1.38447438761828 0.167187001043715 CARS2 other 9.82062828772460e-12 1 1.00947785327498e-10 8.17839885394497 -1.38447438761828 1.63339345451008e-17 335.517895086253 104.719691310393 3.20396184220754 0.00149336528452194 -911.523539102408 191.330508672928 -4.76413064191775 2.89206764989193e-06 ARHGAP32 other 2.3174586332589e-13 0.043031074562742 1 3.20396184220754 -4.76413064191775 1.50710257694527e-25 994.661765828978 134.036082618125 7.42085076197592 1.06419891099694e-12 -583.370235303445 248.202102803187 -2.35038393597346 0.0193627863706691 STT3A other 2.25146053969854e-21 1 1.4936031715842e-08 7.42085076197592 -2.35038393597346 3.06897334833354e-06 862.991057874722 175.152119352085 4.92709457965487 1.34890448092807e-06 645.00752156561 320.79414356346 2.01065865604873 0.0452107178968316 ETS1 other 0.0306038022295821 1 0.0159818202900358 4.92709457965487 2.01065865604873 7.22859296221621e-19 394.739982468865 72.9882357028085 5.40826858832644 1.25030813570432e-07 -391.195776669678 135.156393916291 -2.89439341591169 0.00406069113944276 SLC37A2 other 1.0391825242482e-14 1 0.00155038208827335 5.40826858832644 -2.89439341591169 3.18594619219294e-05 331.826698555376 95.659122383852 3.46884531538825 0.000594288283713361 -205.090781454845 141.367505387971 -1.45076324924877 0.147825315932748 TMED7 other 0.290175979184933 1 1 3.46884531538825 -1.45076324924877 0.0242404266777909 81.4758521377111 61.1132977770317 1.33319351272731 0.183416626229258 -148.449885225176 86.5594470885898 -1.715005007752 0.0873123990849985 APC ts 1 1 1 1.33319351272731 -1.715005007752 0.219667908490856 198.814340436855 119.40733309458 1.66500947039307 0.096889583511859 188.412981436418 169.125756700278 1.11404072988315 0.266097762073018 NREP other 1 1 1 1.66500947039307 1.11404072988315 1.47377804662759e-11 241.328718003685 42.0362020488663 5.74097340485577 2.18688730214238e-08 -121.741797831967 59.6858430033324 -2.03970978218687 0.0422002156725046 WDR36 other 1.88673065529264e-07 1 0.000279374852848689 5.74097340485577 -2.03970978218687 2.86617362058092e-11 252.656692515401 47.5822587383617 5.30989278808038 2.05634441602383e-07 -347.864591880506 91.6184373857578 -3.79688414042502 0.000175281200498471 OSTF1 other 3.64663269746511e-07 1 0.0025286867283845 5.30989278808038 -3.79688414042502 0.000253556549461354 65.3630978573879 17.4538665614596 3.74490647257027 0.000213958313998901 -32.1599269186546 33.7176416864321 -0.953801194571556 0.340904207731446 RFK other 1 1 1 3.74490647257027 -0.953801194571556 5.42345832516989e-13 805.297186572848 110.85177358688 7.26463060098624 2.88905205270404e-12 -341.531277564395 212.202867489652 -1.60945646778807 0.108505680300771 UBQLN1 other 7.18499758918507e-09 1 4.03022761352214e-08 7.26463060098624 -1.60945646778807 6.10876453926551e-15 108.776000941961 14.5909203462723 7.45504727326889 8.5359069317184e-13 -74.1935052701812 28.1898616509287 -2.63192158191159 0.00890311327741371 NAA35 essential 8.39222072404296e-11 1 1.19886812855985e-08 7.45504727326889 -2.63192158191159 8.82916322865786e-09 49.6675950265007 10.5280842051531 4.71762896825902 3.57020883345519e-06 -63.5700161014524 20.2715602225952 -3.13592123168672 0.00187215873762563 C9orf40 other 0.000102771459981578 1 0.0412537630705747 4.71762896825902 -3.13592123168672 0.0241755008421652 3539.96118107329 2996.93130322021 1.18119530376609 0.238402276181468 -12697.9567904582 5770.51552897659 -2.20048914636751 0.0284863631517982 ANXA1 other 1 1 1 1.18119530376609 -2.20048914636751 0.00371014289680598 430.262680324692 145.137504715275 2.96451755298373 0.003259973653351 -307.592674651119 277.65568586674 -1.107820550085 0.268773913266673 CTSL other 1 1 1 2.96451755298373 -1.107820550085 0.00139018350674211 216.720359175646 59.2083878468089 3.66029826274567 0.000294589998312824 100.101631826267 114.762098005787 0.872253414373968 0.38372413609148 TMEM2 other 1 1 1 3.66029826274567 0.872253414373968 0.00050424535033471 46.8200529367297 17.5352030428572 2.67006049615156 0.00797099404625314 -79.2767268423416 33.8387756533605 -2.34277763635543 0.0197531005496501 AGTPBP1 other 1 1 1 2.67006049615156 -2.34277763635543 0.795183762184608 65.9698679351964 106.58072274924 0.618966227977343 0.536380366216904 -32.0118878066147 205.315049710208 -0.155915934325311 0.876197903691864 GOLM1 other 1 1 1 0.618966227977343 -0.155915934325311 0.0280063274756343 -18.5139693969471 16.6988083360861 -1.10870003561503 0.26839739971021 -84.7925961769934 32.4627162221383 -2.61199942718189 0.00942853344786622 FAM189A2 other 1 1 1 -1.10870003561503 -2.61199942718189 0.00515655157486781 181.360465815445 87.1237974145004 2.08164096604518 0.0381697879359003 -349.386048775414 167.71264340326 -2.0832421556634 0.0380226340766093 PSAT1 other 1 1 1 2.08164096604518 -2.0832421556634 4.51953422632704e-09 102.522025882091 16.8199473595889 6.09526437213516 3.15007098430272e-09 -24.6961752703569 32.4016223494945 -0.762189467057418 0.446510104577475 ISCA1 other 5.3330503870659e-05 1 4.1363582094879e-05 6.09526437213516 -0.762189467057418 0.00501009604450572 77.9998426144414 106.042698786384 0.735551277995732 0.462542593151926 -421.096063624559 152.051692811217 -2.76942700103562 0.00594319703621189 ADAM19 other 1 1 1 0.735551277995732 -2.76942700103562 0.00212653969217042 -10.1567668765719 27.2447467526049 -0.372797257717245 0.709546146189241 -136.597641338491 39.6404502863444 -3.44591548157936 0.000645078072639417 HAVCR2 other 1 1 1 -0.372797257717245 -3.44591548157936 1.47854957696794e-06 104.442483296045 28.8876206759985 3.61547544768275 0.000348141997471071 -100.924407523306 41.4211602999854 -2.43654225985893 0.0153733447838593 CCNJL other 0.0151092981270354 1 1 3.61547544768275 -2.43654225985893 0.00155716208991012 106.833644833213 32.4980090482506 3.28739045750754 0.00112397847400782 -96.4693401894931 89.9171847301312 -1.07286877896619 0.284140927307987 TAOK3 other 1 1 1 3.28739045750754 -1.07286877896619 0.0105669508948719 22.3732037029866 9.26286100698566 2.4153664495358 0.0162794214970539 -38.076829221056 25.9775285918863 -1.46576026608431 0.143695506668911 USP30 other 1 1 1 2.4153664495358 -1.46576026608431 0.0449550767507382 -6.84374854582822 20.2243158100365 -0.33839209247474 0.735289645076961 129.830182694781 53.892129574094 2.40907501189544 0.0165575549418069 SDS other 1 1 1 -0.33839209247474 2.40907501189544 0.601330291219249 11.3280014673699 16.7545372213665 0.676115449665998 0.499457231039566 38.7679278458755 46.3573265723665 0.836284805711489 0.403620689865698 MSI1 other 1 1 1 0.676115449665998 0.836284805711489 0.0361121678349623 9.42339631927402 3.95447618245482 2.38296954754302 0.0177587632448004 -6.67377309132793 10.5420299025179 -0.633063380870691 0.52714581604566 HNF1A other 1 1 1 2.38296954754302 -0.633063380870691 0.00617963817747156 128.786126599258 44.6246110074357 2.88598877820578 0.00416783851320157 -120.37159305326 121.172672026481 -0.993388946865459 0.321273355605706 FBXO21 other 1 1 1 2.88598877820578 -0.993388946865459 0.463051148044374 35.1522629415981 28.8847815864449 1.21698212729759 0.224510590190333 31.2776601638787 78.0398342937811 0.40079096075645 0.688842338156664 TBX3 other 1 1 1 1.21698212729759 0.40079096075645 0.94783912686853 49.8060322161901 171.093501103932 0.291104173418808 0.771160239506977 88.0759516630131 456.291794809931 0.193025499614126 0.847061449946827 OASL other 1 1 1 0.291104173418808 0.193025499614126 0.776267767970604 5.40500417991191 9.9364286959168 0.543958432684472 0.586850049371065 14.1400392964969 26.5975130331468 0.531630129436354 0.595352200458051 HRK other 1 1 1 0.543958432684472 0.531630129436354 0.385113926642943 -1.77553074232042 10.5622279966029 -0.168101913998778 0.866609629170055 37.7650740403509 28.2726324916069 1.33574664656933 0.182584297854238 RNFT2 other 1 1 1 -0.168101913998778 1.33574664656933 0.485235980224792 -25.322010995006 22.6840916600048 -1.11628939675165 0.265135786112691 16.7743036784146 59.7050255984491 0.280952960161705 0.778928046789289 P2RX4 other 1 1 1 -1.11628939675165 0.280952960161705 0.311713873934547 -57.4648863674853 47.0683327476462 -1.22088213057343 0.223035103241229 -140.854497018363 130.179370181528 -1.08200321465644 0.280070901237334 BICDL1 other 1 1 1 -1.22088213057343 -1.08200321465644 0.116360754023444 15.588331334983 7.49562234182402 2.07965804893922 0.038352697707178 4.68595925066116 20.0698615870697 0.233482390017087 0.815536129371127 DTX1 other 1 1 1 2.07965804893922 0.233482390017087 0.0515964407344641 69.5058108395323 58.3535994021351 1.19111437086414 0.234491426113077 -302.494899043571 156.232650615006 -1.93618233994499 0.0537257400827684 TRAFD1 other 1 1 1 1.19111437086414 -1.93618233994499 0.016110658810722 61.5159315380498 24.5856913206084 2.50210298078889 0.012859048573609 -62.7626239903613 95.4400840389489 -0.657612832410626 0.511273366128034 DMTF1 other 1 1 1 2.50210298078889 -0.657612832410626 5.64491361858698e-05 25.544141479129 8.84328392023684 2.8885357192563 0.00414202404741416 -84.0678546120547 34.3290635809872 -2.44888283695029 0.014881757567476 TMEM243 other 0.50064738883248 1 1 2.8885357192563 -2.44888283695029 0.106767752464571 -32.3627926231747 20.1461524041203 -1.60640066519877 0.109175280211223 -123.484270665266 69.7924256057498 -1.76930762319131 0.0777979495365136 CCDC146 other 1 1 1 -1.60640066519877 -1.76930762319131 1.54152581771029e-07 40.4980128153133 7.56697339783476 5.35194333138552 1.665614694614e-07 -16.6633625548525 26.5393714079928 -0.627873294309976 0.530536157266915 TMEM60 other 0.00168334619293964 1 0.00205503541021475 5.35194333138552 -0.627873294309976 0.00175126496461137 403.541580412854 112.186281228405 3.59706709228793 0.000373186307799479 332.477039477523 412.32510001321 0.806346835220245 0.420647396755593 CD36 other 1 1 1 3.59706709228793 0.806346835220245 1.28792255032783e-19 224.917341930678 23.695351908583 9.49204480264365 5.93932022909714e-19 -108.187797542072 101.30725895614 -1.06791752789315 0.286378043681488 PNPLA8 other 1.86465426836463e-15 1 8.77296991039939e-15 9.49204480264365 -1.06791752789315 5.66473133336571e-05 271.849469277364 79.6653223741278 3.41239401506082 0.000726936545104624 -191.448766191948 183.2729084785 -1.04461029063882 0.296994051547478 HILPDA other 0.502291727329538 1 1 3.41239401506082 -1.04461029063882 3.76929035524375e-16 118.960404540411 13.8953178476185 8.56118628195321 5.0638851375824e-16 -9.01149953059667 51.3222997161013 -0.175586432806897 0.86073203836169 RINT1 essential 5.2638139810979e-12 1 7.35073566571461e-12 8.56118628195321 -0.175586432806897 2.4068754001546e-14 330.063802470704 43.5486738909554 7.57919295768166 3.97120437351569e-13 -255.732694235119 168.055757602677 -1.521713375865 0.1290905008224 SRPK2 other 3.27262848159021e-10 1 5.60019240753183e-09 7.57919295768166 -1.521713375865 2.13330080641409e-07 75.8919674594553 23.7831543056433 3.19099672331721 0.00155889724086912 -149.261193185555 54.7139926443552 -2.72802597601975 0.00672442048361676 KCP other 0.00231207141399159 1 1 3.19099672331721 -2.72802597601975 2.54743874196924e-12 483.794494831044 88.8238734876445 5.44667188938051 1.03761160645519e-07 -641.704335503196 231.713693440611 -2.76938460552254 0.00595029873542497 TES other 3.32440755826986e-08 1 0.00129078883843026 5.44667188938051 -2.76938460552254 0.00111769553610289 68.5937826189823 36.0503618707339 1.90272105630838 0.0579915170014997 -213.459929392226 94.9195226676991 -2.24885169449831 0.0252148929287742 MDFIC other 1 1 1 1.90272105630838 -2.24885169449831 0.000155017104628701 32.8760673897993 13.9360274350422 2.35907022593342 0.0189289767210244 -100.925164812009 33.7983239723552 -2.98609969223796 0.00304645845278137 MTO1 other 1 1 1 2.35907022593342 -2.98609969223796 0.202488233937862 -4.93079019640792 19.2664624900342 -0.255926078747379 0.798172352700566 -81.9079377208199 46.0900394409637 -1.77712882684197 0.0764968597328021 ANKRD6 other 1 1 1 -0.255926078747379 -1.77712882684197 0.421135602954955 5.95936371687447 5.19643014202909 1.14681878789724 0.252326868733874 -5.03204963020225 12.4224396066994 -0.405077407459359 0.685695569397963 KHDC1 other 1 1 1 1.14681878789724 -0.405077407459359 0.0307562478131594 -3.56642283390785 9.29033911256161 -0.383885108035038 0.701320958149826 -53.2377612565025 20.2140105926109 -2.63370601358858 0.00886009601821565 CEP162 other 1 1 1 -0.383885108035038 -2.63370601358858 1.22230209161306e-11 742.441934656423 140.531090013711 5.28311517817149 2.36159381717983e-07 -1116.78792692311 312.516229697783 -3.57353577445592 0.000406776526447072 SYNCRIP other 1.56858027416704e-07 1 0.00289696713553449 5.28311517817149 -3.57353577445592 1.66942975080185e-09 133.178097834865 27.0012549400606 4.93229289270085 1.31219525478065e-06 -172.766142562631 60.0460039849765 -2.87722964222327 0.00428310626738983 SNX14 other 2.0001437844357e-05 1 0.0155560747454246 4.93229289270085 -2.87722964222327 0.007432263056322 392.320029641169 166.808052261752 2.35192500794594 0.0192860748684555 -522.312484443137 370.951535144197 -1.40803429817349 0.16009775115956 NT5E other 1 1 1 2.35192500794594 -1.40803429817349 0.442321435904863 -5.09379117447158 26.0165779436142 -0.195790206748611 0.844899819053152 -71.3095440313957 56.1205316503251 -1.2706498305417 0.204784967395787 MRAP2 other 1 1 1 -0.195790206748611 -1.2706498305417 0.126465036172874 9.36745733905029 57.4654733372998 0.163010183246329 0.87061461293943 274.377911301269 137.139163504793 2.00072615501757 0.0462770356614563 EPHA7 other 1 1 1 0.163010183246329 2.00072615501757 1.19213034200985e-13 176.518065644167 30.4275071725284 5.80126609266032 1.58563120249613e-08 -281.18946026883 73.3039101021332 -3.83594080966558 0.000150757754023358 AKIRIN2 essential 1.59983891897721e-09 1 0.000203706040584678 5.80126609266032 -3.83594080966558 1.32407476563432e-05 61.0162609945819 21.2890471186892 2.86608699085536 0.00443190983565255 -151.257865560041 51.2881448782449 -2.94917794198091 0.00342163933478036 ORC3 essential 0.125072102361818 1 1 2.86608699085536 -2.94917794198091 0.237986390305834 4.83890459795113 9.09185964078392 0.532223856189437 0.59494144814429 -27.6295484808778 19.6028547085359 -1.40946555446573 0.159671672044399 LCA5 other 1 1 1 0.532223856189437 -1.40946555446573 1.47485724937449e-14 174.555914108867 29.9250673021058 5.83310013463474 1.33145045530968e-08 -297.443783237078 71.8166575819969 -4.14171019999741 4.41560591948432e-05 MAP3K7 other 2.01244271677149e-10 0.638231679602264 0.000171344359093803 5.83310013463474 -4.14171019999741 0.0262265379098634 -2.72696542643806 25.6406533648622 -0.106353195748712 0.915370040033929 -168.543998449675 66.4468708994986 -2.53652273113958 0.0116800424740386 PRR5L other 1 1 1 -0.106353195748712 -2.53652273113958 0.582315511611138 16.0613045287424 15.9983124144492 1.0039374224394 0.316172079185213 26.0332088263682 39.8982196131956 0.652490489018165 0.514556188367726 LMO2 other 1 1 1 1.0039374224394 0.652490489018165 3.87320311288249e-07 64.2495611883505 33.9219025023825 1.89404356621324 0.059149960048832 -315.977139968865 83.6172231494188 -3.77885234725188 0.000188921220645672 PHF21A other 0.00412883451833274 1 1 1.89404356621324 -3.77885234725188 7.09727019159633e-25 580.85489156607 57.5729936550931 10.0890166498175 5.8913300517454e-21 -172.013494045723 148.297369689136 -1.1599227579444 0.246947656302199 NAT10 essential 1.05735131314402e-20 1 8.78043830912135e-17 10.0890166498175 -1.1599227579444 0.0140129257053969 -74.4583486572121 203.388850335045 -0.366088645147243 0.71454312387188 -1513.24185257974 535.709723014821 -2.82474218325486 0.0050317082858836 EHF other 1 1 1 -0.366088645147243 -2.82474218325486 0.0238767010238908 54.0529507908507 24.6155190107574 2.1958891367364 0.0288240663389234 -42.0808000287942 64.8352790696057 -0.649041704341509 0.516781362692417 ELF5 other 1 1 1 2.1958891367364 -0.649041704341509 1.8005751439298e-13 756.898906689352 131.687310386608 5.74769812267595 2.11477690334899e-08 -1104.22934098738 353.550482904055 -3.12325790624657 0.00195261436555118 PRRG4 other 2.40844931252051e-09 1 0.000270395374862202 5.74769812267595 -3.12325790624657 4.07449650823935e-22 1439.70564595088 181.388396264521 7.93714303450447 3.57883156911331e-14 -1649.89313724152 467.186782849736 -3.53154925997164 0.000474239970768037 CAPRIN1 other 5.99195456501678e-18 1 5.11916067645968e-10 7.93714303450447 -3.53154925997164 0.0176019421824428 387.77111928316 154.860383234818 2.50400464717419 0.0127770237316846 -375.336895259834 431.281033453008 -0.870283796750199 0.384797692702535 ATP5G2 other 1 1 1 2.50400464717419 -0.870283796750199 0.00192672342124509 110.43737564496 38.5001857535869 2.86848942370806 0.00439837076358212 -168.932211147029 109.99843323679 -1.53576924848897 0.125583102747416 DNAJC14 other 1 1 1 2.86848942370806 -1.53576924848897 0.296351180928781 515.96420261019 388.273932749559 1.32886644992208 0.184838789475993 -611.604646121086 1109.33294043027 -0.551326498863242 0.581794626087804 CD63 other 1 1 1 1.32886644992208 -0.551326498863242 0.178886082071615 8.93700923260326 6.80303913467992 1.31367893902667 0.189901227296407 -18.2145968235722 18.0124906502708 -1.01122033466807 0.31267977903218 PRPH other 1 1 1 1.31367893902667 -1.01122033466807 0.0845449842509895 11.1015762958169 6.07108437790867 1.82859858383999 0.0683904550335386 -18.1544416087607 19.8915899165642 -0.91266920768576 0.362103617930116 AVIL other 1 1 1 1.82859858383999 -0.91266920768576 0.00892809184106985 65.530098135096 21.2366960038887 3.0857011901991 0.00220802541545669 21.8845672083287 60.675117322937 0.360684382229544 0.718573377238325 GDF11 other 1 1 1 3.0857011901991 0.360684382229544 0.147950393776581 -38.8135264560077 25.4642688815216 -1.52423486559134 0.128437698046864 -109.378711380684 72.753666655407 -1.50341166856578 0.133719162147124 GLS2 other 1 1 1 -1.52423486559134 -1.50341166856578 0.178764983776055 127.843725761306 70.4179408551228 1.8154993487289 0.0703830889602245 -10.2180217853168 201.190280363849 -0.0507878500235579 0.95952625942846 ITGA7 other 1 1 1 1.8154993487289 -0.0507878500235579 0.029401905227857 -13.3974374326428 5.01681610404187 -2.67050598523016 0.00796188551563087 -7.07648784576697 14.2581593737433 -0.496311456498267 0.620016487445055 TESPA1 other 1 1 1 -2.67050598523016 -0.496311456498267 0.669020879144818 0.99863249684764 1.26356089431853 0.790331911455861 0.429921082342426 -0.905054433729383 3.4285767888502 -0.263973797137237 0.79197055836423 FAM186B other 1 1 1 0.790331911455861 -0.263973797137237 0.300978501499183 6.9481671331737 5.88469977819723 1.18071735093719 0.238591882760692 -12.8185367898213 16.8131073396256 -0.762413308312749 0.446374970185423 RDH5 other 1 1 1 1.18071735093719 -0.762413308312749 1.36014264943513e-05 61.4690685715881 12.8097957321596 4.79859865503297 2.45510422932459e-06 19.9754570883029 41.9706246459462 0.475938999164557 0.634442596307724 AGAP2 other 0.128343060400699 1 0.0286387908350714 4.79859865503297 0.475938999164557 0.568703624428986 -57.3893197990084 62.9744581735156 -0.911311053139699 0.362817478823566 65.2431047689705 179.923592508306 0.362615618437913 0.717131420172791 BLOC1S1 other 1 1 1 -0.911311053139699 0.362615618437913 0.112056012706142 74.8134964647164 47.2137026156816 1.58457168830194 0.114054489502795 -132.633489935287 128.167060790902 -1.03484849474447 0.301523523333753 KRT85 other 1 1 1 1.58457168830194 -1.03484849474447 7.39729672971106e-08 743.187323807816 128.165573760273 5.7986501523249 1.60403673851733e-08 53.4383979316117 419.927788178546 0.127256160311283 0.898817584750184 CDK4 essential 0.000821469801834413 1 0.00020600643832778 5.7986501523249 0.127256160311283 0.127536930099244 100.764807939207 50.7000109530808 1.98747112761883 0.0477249985992921 -6.50340950833446 141.135623123375 -0.0460791497172151 0.963275997002416 PPP1R1A other 1 1 1 1.98747112761883 -0.0460791497172151 0.474492865780679 23.7013394865346 40.9485561672758 0.578807696899351 0.563128666968657 -100.925821542592 108.419997372225 -0.930878288034777 0.352622668219902 TROAP other 1 1 1 0.578807696899351 -0.930878288034777 4.11601566644206e-11 499.030579215461 69.7565039439284 7.15389319993146 5.78120993981193e-12 163.710706313823 228.55353081813 0.716290427576441 0.474334437822885 TSPAN31 other 5.21540345094874e-07 1 8.02547563844692e-08 7.15389319993146 0.716290427576441 0.39831269077902 31.6472695839317 36.8470930047298 0.85888104062563 0.391049052527711 -105.380741973956 120.727569910677 -0.87288050320175 0.383382723060042 B4GALNT1 other 1 1 1 0.85888104062563 -0.87288050320175 0.00184455282557183 92.7873261577112 30.8530513089927 3.00739545105111 0.00284445503783604 -108.440713917046 84.1343374316724 -1.28889960065489 0.198366887193999 TFCP2 other 1 1 1 3.00739545105111 -1.28889960065489 0.409232444501257 26.3766903854585 19.7830016406328 1.33330072274183 0.183381493512961 7.8630348170024 56.5217840536707 0.139115120809633 0.889446688984426 COQ10A other 1 1 1 1.33330072274183 0.139115120809633 0.693606385535094 1.01617038533976 3.27750021356482 0.310044338405857 0.756729688706444 -6.30491057312933 8.80614680235489 -0.71596700743659 0.47453548379523 FAIM2 other 1 1 1 0.310044338405857 -0.71596700743659 0.188671564808094 45.7484234310188 32.0018096441506 1.42955738877664 0.153819623547097 -77.5473548809803 91.4319983838153 -0.848142403663215 0.396992623742249 PAN2 other 1 1 1 1.42955738877664 -0.848142403663215 0.623869298240153 39.1472805588256 43.2322971862043 0.90551007248622 0.365880774352366 -17.9487106185553 117.310741449664 -0.153001425076294 0.878494189137963 ESPL1 essential 1 1 1 0.90551007248622 -0.153001425076294 0.797055916717842 377.603051618271 687.754778518857 0.549037336289359 0.58336392159312 -507.395630011703 1884.9268910071 -0.269185840805001 0.787960699213366 KRT7 other 1 1 1 0.549037336289359 -0.269185840805001 0.919862355889898 2.43260378376555 7.51836633263867 0.323554835736742 0.746486434799112 6.6024565088572 21.480637064548 0.307367816374218 0.758763360471477 ZC3H10 other 1 1 1 0.323554835736742 0.307367816374218 0.588785898945966 188.134873361992 188.731619167571 0.996838124908741 0.319596265293656 -32.1667955580396 525.611302643019 -0.0611988277198188 0.951239067666003 HNRNPA1 other 1 1 1 0.996838124908741 -0.0611988277198188 0.454219469992248 13.9039068896146 12.6736995562576 1.09706773684323 0.273436644071425 -16.5425473704709 41.5247126553132 -0.398378370677401 0.690616969105606 SLC26A10 other 1 1 1 1.09706773684323 -0.398378370677401 0.00250125178986551 129.287897677861 54.6739019602453 2.36470954225782 0.0186425718446696 -302.853635457347 149.092304361115 -2.03131634966086 0.0430516316366848 ACVR1B other 1 1 1 2.36470954225782 -2.03131634966086 4.90676295426731e-12 1687.67914931316 230.14233561949 7.33319727885056 1.85593106727228e-12 -196.934973854873 754.049306124147 -0.261169889363242 0.794129501035033 OS9 other 6.3640715516847e-08 1 2.59589078379373e-08 7.33319727885056 -0.261169889363242 0.000144976156184152 5.94729032475634 1.40274893459307 4.2397396840523 2.93186867832164e-05 1.50749502579839 4.00777767716195 0.376142377953935 0.707060302503429 MIP other 1 1 0.318518213212863 4.2397396840523 0.376142377953935 0.361828191871693 -4.30324826398141 10.1451104316229 -0.424169681836872 0.671727970001743 -39.0888024579539 27.5279887994189 -1.41996579346105 0.156594175912044 KCNH3 other 1 1 1 -0.424169681836872 -1.41996579346105 6.90063119566513e-08 94.1903589326004 23.6756447026437 3.97836511383713 8.59840662943922e-05 -171.852100303688 52.0100822337544 -3.30420743292263 0.00106113594547498 LTV1 essential 0.000767281182646005 1 0.897759636179749 3.97836511383713 -3.30420743292263 1.44690038624621e-06 218.310073389135 58.8141785120732 3.7118613047417 0.000242838525881749 -391.367699801507 136.932471472904 -2.85810732539762 0.00454289759097772 MAP7 other 0.0148075785528437 1 1 3.7118613047417 -2.85810732539762 2.46596953868971e-09 487.037901256786 172.99287618646 2.81536391551658 0.00517523069149524 -1922.73283840332 390.863810512216 -4.91918869614362 1.39451200533313e-06 CD164 other 2.93992888402587e-05 0.020854927039757 1 2.81536391551658 -4.91918869614362 1.24043083841168e-07 10.2226773352513 2.81724549328554 3.62860721922014 0.000331726772283383 -21.8922319518115 6.41685483240887 -3.41167636226442 0.000728784722796295 AFG1L other 0.00136124880207298 1 1 3.62860721922014 -3.41167636226442 2.01991693141836e-06 149.035432935527 48.1066571017498 3.09802097909866 0.00212252264410185 -387.497196219719 111.955989580575 -3.46115645684893 0.000611606055749265 NHSL1 other 0.0203910614226683 1 1 3.09802097909866 -3.46115645684893 0.425282373656632 7.38263754017514 11.6540113050898 0.633484672951263 0.526872528515039 -26.4868965512403 27.1331269253643 -0.976182974564575 0.329715806719176 AHI1 other 1 1 1 0.633484672951263 -0.976182974564575 0.336477127253999 -5.71908203483248 6.85195172322904 -0.834664671591895 0.404535104917905 -22.3489902785794 16.124318340902 -1.38604248601861 0.166708124239083 HEY2 other 1 1 1 -0.834664671591895 -1.38604248601861 0.905009524294089 4.00364908915741 13.5202079506333 0.296123336547489 0.767329181127555 -8.04128595749549 31.4026691496976 -0.256070142291485 0.798062244330908 PKIB other 1 1 1 0.296123336547489 -0.256070142291485 0.000166054438728671 24.7727207027459 13.2306581329288 1.87237251948117 0.0620697496805866 -94.872194408585 29.8936324282338 -3.17365896019316 0.00165199579545966 SMPD2 other 1 1 1 1.87237251948117 -3.17365896019316 0.126711511207439 55.7355889067282 60.9971964289697 0.913740174462468 0.361543484951573 -209.754704976272 137.818372365182 -1.52196475242414 0.129008534808293 MICAL1 other 1 1 1 0.913740174462468 -1.52196475242414 0.000182979166278754 86.0863179142929 36.9079427835669 2.33246047928259 0.020300163931489 -248.842840048003 85.1994585081578 -2.92070917357035 0.00374204166601039 REPS1 other 1 1 1 2.33246047928259 -2.92070917357035 0.0278775700150302 10.0198121460568 18.0419938915791 0.555360577454434 0.579037291450942 -96.4112411277898 39.6374495813854 -2.43232705802208 0.0155517953163151 STX11 other 1 1 1 0.555360577454434 -2.43232705802208 0.00905410377194114 7.00872797787395 4.31066139645304 1.62590547790206 0.105012778791607 -14.3636994044028 9.3551708991525 -1.53537541529082 0.125738603554562 TEC other 1 1 1 1.62590547790206 -1.53537541529082 0.420729843203308 0.40276334148006 19.0341632893913 0.0211600234460813 0.98313119162543 -103.76308396775 78.9932156020291 -1.31356956641078 0.189932095801366 PRADC1 other 1 1 1 0.0211600234460813 -1.31356956641078 1.34938435493392e-08 106.570633936559 17.2160165134657 6.19020281800981 1.83965838091123e-09 43.7848147159918 71.2397102661605 0.614612475996972 0.539247429166186 SEMA4F other 0.000155624497654528 1 2.43110855037419e-05 6.19020281800981 0.614612475996972 2.36305197825694e-05 887.47391165922 200.746879806706 4.42086030185746 1.34827443587796e-05 -1080.41476809844 833.114716781066 -1.2968379340037 0.195621257134868 CCT7 essential 0.217967914474421 1 0.149928117269629 4.42086030185746 -1.2968379340037 0.918736890285677 1.16506384745281 3.94561020130265 0.295281030819559 0.767970700475191 4.99327190493585 16.3745804096773 0.304940449160141 0.760609745425001 EGR4 other 1 1 1 0.295281030819559 0.304940449160141 0.000364184707873756 207.100218385207 53.0908147227398 3.90086721152732 0.000116845636602052 274.262718974376 219.590001143071 1.24897635387179 0.212586602819881 RAB11FIP5 other 1 1 1 3.90086721152732 1.24897635387179 8.36336777515919e-06 105.50625208741 21.6836708828648 4.86570067666841 1.7932328517263e-06 -41.1714189397984 89.9888722741098 -0.457516778456659 0.647610117265119 SMYD5 other 0.0803886910548302 1 0.0210686927749323 4.86570067666841 -0.457516778456659 0.02043660926207 146.543645397409 52.2167334851567 2.80644987950205 0.00531601392716875 39.8330168603193 217.52918165699 0.183115739032797 0.854823170766439 DYSF other 1 1 1 2.80644987950205 0.183115739032797 0.0811620933483871 68.5566995746548 36.8150798679032 1.86219070610859 0.0634926164381048 -174.612449578578 152.340445373273 -1.14619889124476 0.252569244610173 CCDC142 other 1 1 1 1.86219070610859 -1.14619889124476 0.351979678470952 7.20887209539823 6.11304222222319 1.17926096914418 0.239170296838326 -19.3296831057833 25.2842785626093 -0.764494152281974 0.445136192335984 EMX1 other 1 1 1 1.17926096914418 -0.764494152281974 3.39127348134314e-10 33.6727870341291 5.25717903634391 6.40510562819766 5.46216502477187e-10 90.0669682643418 29.8846670194879 3.01381869858576 0.00278925232014435 KCNMB4 other 4.17431852818527e-06 1 7.31493140117449e-06 6.40510562819766 3.01381869858576 0.00103477179991687 321.69945806869 86.261464863489 3.72935306139059 0.000227602554201505 26.7874316074735 348.696522424081 0.076821619617115 0.938814221643706 GNS other 1 1 1 3.72935306139059 0.076821619617115 0.387384620682645 36.2217298806018 27.341457235807 1.32479149038059 0.186200566431421 87.1600769111493 171.269551225523 0.508905852134683 0.611174483497034 CPM other 1 1 1 1.32479149038059 0.508905852134683 5.7289584474011e-05 202.738093968058 48.9334888282294 4.14313589369699 4.40634693574922e-05 -405.794763839355 306.524140217891 -1.32385907208123 0.186509749602701 MDM2 og 0.507471139270789 1 0.472536645389746 4.14313589369699 -1.32385907208123 1.60889669417125e-12 182.427055298942 35.5352801646188 5.13368839231998 4.94196166726054e-07 -252.456695392283 91.0483180678449 -2.77277714459441 0.00588380424312663 KLHL36 other 2.11022890407501e-08 1 0.00597483165571799 5.13368839231998 -2.77277714459441 0.52288854345063 4.12120459759696 4.22984961013618 0.974314686678487 0.330636244577652 10.5572314694529 10.8368516923603 0.974197282490769 0.330694432870967 BCO1 other 1 1 1 0.974314686678487 0.974197282490769 9.60845569808282e-09 47.8633074304208 26.3396246410485 1.81715981464023 0.0701278829364045 -298.944498557275 67.2499566017322 -4.44527422266878 1.21182010994084e-05 MPHOSPH6 other 0.000111650255211722 0.177967901345911 1 1.81715981464023 -4.44527422266878 0.0018516906807578 16.1321865314485 36.5143886914426 0.441803549493057 0.65892977821878 -277.80811872048 93.5496652027828 -2.96963242057884 0.00320692190199407 KIAA0513 other 1 1 1 0.441803549493057 -2.96963242057884 1.13540477112148e-16 386.449989438038 65.5311972358327 5.89719104394335 9.39453949338627e-09 -687.826115094457 176.535343354519 -3.89625160619063 0.00011899034926507 DYNC1LI2 other 1.59399475817745e-12 1 0.000121452606570498 5.89719104394335 -3.89625160619063 0.0240718615220905 9.73838648510928 5.12982409823019 1.89838604572602 0.0585475907116065 -14.3147352101854 13.8183756062632 -1.03592025705954 0.301023979516364 FBXL8 other 1 1 1 1.89838604572602 -1.03592025705954 1.18732609110058e-08 99.8738928276067 32.9461752858815 3.03142601412692 0.00263404287779096 -328.210718502664 88.1869641269613 -3.72176003281102 0.000233895657040143 FHOD1 other 0.00013729051591396 1 1 3.03142601412692 -3.72176003281102 0.00276405881551944 38.6493125702376 11.1628920461372 3.4623028163756 0.000608385042924706 48.9695597283511 29.3840158977903 1.66653734120916 0.0965848854766834 CCDC102A other 1 1 1 3.4623028163756 1.66653734120916 1.25033146126635e-05 16.3570153579357 4.40216095847783 3.71567862061808 0.000239352307645719 -15.4693117314612 11.7832557848606 -1.31282151672686 0.190189718770711 SLC9A5 other 0.118331369494247 1 1 3.71567862061808 -1.31282151672686 0.771223704620836 8.21129858193275 15.0374999711691 0.546054769587763 0.585408769624144 -24.8109446903761 50.7352371764243 -0.489027864482031 0.625156972293302 AGT other 1 1 1 0.546054769587763 -0.489027864482031 1.45779922828357e-06 12.1544134857083 2.44831633818707 4.96439667380088 1.12265420615107e-06 15.3485215962876 7.77911765455157 1.97304145249779 0.049351147683669 ZNF670-ZNF695 other 0.0149074549084278 1 0.0133528491279608 4.96439667380088 1.97304145249779 7.15012246530064e-06 91.1486266310382 18.4915948929618 4.92919227133462 1.32978448845073e-06 -43.9429500971682 59.3370202673258 -0.740565500242445 0.459501667359481 PCNX2 other 0.0691416842394572 1 0.0157579461881412 4.92919227133462 -0.740565500242445 0.00319414338295115 210.344687979536 61.6270012226468 3.41319038418891 0.000724622250902614 -71.737268636389 197.907370554659 -0.362479014477009 0.717233382277588 KCNK1 other 1 1 1 3.41319038418891 -0.362479014477009 9.74824531125527e-08 120.523774635648 20.7625215923454 5.80487173003506 1.55107488345257e-08 22.5985038983726 69.8695699395448 0.323438428459287 0.746574496919783 URB2 essential 0.00107688865953437 1 0.000199313122523655 5.80487173003506 0.323438428459287 0.00202775677466992 150.166819852941 42.2512394328897 3.55413999372634 0.000436361623569082 -0.652726715686852 142.552063689805 -0.00457886542496636 0.996349459871679 EGLN1 other 1 1 1 3.55413999372634 -0.00457886542496636 1.21456490259811e-07 94.8900177258399 16.4556360109049 5.76641447726224 1.90798639212971e-08 16.1234157725592 55.519906733357 0.290407832455382 0.771692360445469 COG2 other 0.00133371371954299 1 0.000244603855471029 5.76641447726224 0.290407832455382 0.0182862442050856 42.4833136588179 14.9510218364999 2.84149900410844 0.00477916199604842 3.5896987460371 50.1823221583778 0.0715331334151463 0.943018281507621 ABCB10 other 1 1 1 2.84149900410844 0.0715331334151463 1.08801011120797e-06 142.752177920624 27.185722544171 5.2509981181733 2.76370041366507e-07 73.4681144135447 87.3035318708361 0.841525111747362 0.400682247443232 NTPCR other 0.0112358804184447 1 0.00338055834599512 5.2509981181733 0.841525111747362 3.204121351382e-06 102.97607667344 20.1521667554004 5.10992579226473 5.55243892553809e-07 -43.6624673105883 67.8156175918883 -0.643840885934968 0.520139791071831 TAF5L other 0.0318810074462509 1 0.00669901756366171 5.10992579226473 -0.643840885934968 0.75956745698427 869.454760879924 1301.90671548497 0.667831842741545 0.50472532219561 -1412.28209416288 4099.73540461759 -0.344481278614275 0.730712072988313 GLUL other 1 1 1 0.667831842741545 -0.344481278614275 0.000975847423026171 186.210310532351 53.8406371684927 3.45854581827499 0.000616620729373998 -269.17041228854 168.872923013069 -1.59392285918868 0.111940508546406 STX6 other 1 1 1 3.45854581827499 -1.59392285918868 0.251816231226575 31.8466002971357 19.6160187709399 1.62349968507956 0.10547345581671 -25.8439313224999 61.7713125651311 -0.418380802500357 0.675951123990361 RNASEL other 1 1 1 1.62349968507956 -0.418380802500357 0.0410592909145647 345.461495026915 136.047605818576 2.5392691988097 0.0115844970880911 -54.6217759532068 428.417166647845 -0.127496702292757 0.898627867592244 DHX9 essential 1 1 1 2.5392691988097 -0.127496702292757 0.00345317650812171 28.2092762992359 8.30780418384153 3.39551531006259 0.000771303385931954 -5.46785773274478 26.057700096583 -0.209836543995753 0.833928782690185 KIAA1614 other 1 1 1 3.39551531006259 -0.209836543995753 0.00220726211872601 182.649081492084 51.7549254250475 3.52911495847096 0.000478055233728631 0.0582863240959818 162.576527439552 0.000358516232410325 0.999714168831997 CEP350 other 1 1 1 3.52911495847096 0.000358516232410325 0.185573108310363 94.2738460541598 52.6086052086057 1.79198527846046 0.0740859175355081 59.8151485652068 165.665756844127 0.361059217696305 0.718294925240308 NPL other 1 1 1 1.79198527846046 0.361059217696305 0.318503418267769 51.7467749210643 135.247616890929 0.382607665189366 0.702265483249964 -682.337815867288 461.915892355388 -1.47719060365715 0.140611095125223 FAM129A other 1 1 1 0.382607665189366 -1.47719060365715 1.50531134719884e-07 116.85298868113 20.3377426006788 5.74562236210178 2.13311395358268e-08 -11.6751362220245 65.5765593490753 -0.178038255405803 0.858805584111649 PIGC other 0.00164485370908417 1 0.000272675956686474 5.74562236210178 -0.178038255405803 0.0337974546123812 733.266421376709 290.053226390303 2.52804090649902 0.0119523803322657 -693.480379769369 929.775790769313 -0.745857642943758 0.456302662650042 LAMC1 other 1 1 1 2.52804090649902 -0.745857642943758 0.000539821132485006 99.0412970955641 25.2397888382022 3.92401448880816 0.000106762862714622 0.186090679162683 81.2557069706222 0.00229018595863012 0.998174133576217 RC3H1 other 1 1 1 3.92401448880816 0.00229018595863012 0.068389924841629 -4.6061132741364 3.1408529808816 -1.46651667625764 0.143489588980921 -12.4512959516801 5.47062434925848 -2.27602832085662 0.0235047686611473 GPR55 other 1 1 1 -1.46651667625764 -2.27602832085662 0.00207787410890091 40.3776232601543 70.7961924919088 0.570336085019953 0.568850001179285 -352.066347711149 123.31025260925 -2.85512631968072 0.00458287064411695 SP110 other 1 1 1 0.570336085019953 -2.85512631968072 5.46635772659846e-12 52.079392248227 19.9090833798467 2.61586087388359 0.00932349367772782 -174.353309516121 34.7482317762142 -5.01761674202566 8.70749193537277e-07 MRPL44 other 7.08002652749032e-08 0.0130568841570915 1 2.61586087388359 -5.01761674202566 0.133365630424893 35.7514396911785 18.1054835086268 1.97461943914084 0.0491734695403733 17.0100560846729 31.2472746154942 0.544369270407932 0.586567692757119 CHRND other 1 1 1 1.97461943914084 0.544369270407932 0.127651254482286 4.00879625390035 4.39991579519405 0.911107493984109 0.36292454797277 15.6264995454739 7.67872201031896 2.03503910214153 0.0426707855191668 PAX3 other 1 1 1 0.911107493984109 2.03503910214153 0.00534350304115758 -67.4167103677982 30.117216274803 -2.23847747921514 0.0258794074354909 -163.913902629154 52.3097461634308 -3.1335251009829 0.00188756097458273 DOCK10 other 1 1 1 -2.23847747921514 -3.1335251009829 0.00712444635086186 67.7863982700954 44.151975706691 1.53529705489086 0.125702076389631 -135.292026993754 77.5417132913137 -1.74476447902924 0.0819888995324012 TTLL4 other 1 1 1 1.53529705489086 -1.74476447902924 2.35256422288033e-05 -7.76108278523738 31.7842529167897 -0.24418012295446 0.807247803734298 -238.65847832092 55.7656108665826 -4.27967119183726 2.47594736341924e-05 USP37 other 0.217094626487397 0.360621733482013 1 -0.24418012295446 -4.27967119183726 0.000955384063771337 336.743357507307 146.516859892893 2.29832496924568 0.0221877082295411 -410.40442460144 255.197777860323 -1.60818181115224 0.108781500209417 ITM2C other 1 1 1 2.29832496924568 -1.60818181115224 0.478067662927505 -2.49724952655782 3.85800562092874 -0.647290276875402 0.517908161329569 -8.09810082063301 6.68720974294316 -1.2109835240593 0.226795309498135 SLC19A3 other 1 1 1 -0.647290276875402 -1.2109835240593 6.10350760660423e-05 802.59200684995 444.905721573307 1.80395973333804 0.0721808439454986 -2165.99326712245 776.514259186963 -2.78937990062194 0.00559832624217007 SERPINE2 other 0.53900075673922 1 1 1.80395973333804 -2.78937990062194 5.61916431835836e-10 457.878268501795 182.632510964883 2.50710164407604 0.0126678000349892 -1409.23010252687 320.566792347738 -4.39605765839337 1.50191898415502e-05 DNAJB2 other 6.86212346557923e-06 0.22012124631776 1 2.50710164407604 -4.39605765839337 2.5502384095547e-10 271.081215757413 68.3570825983738 3.96566391444947 9.04064106506415e-05 -377.810670204195 120.051825890783 -3.14706309046818 0.0018048397491456 WNT10A other 3.15311476957343e-06 1 0.941492360515781 3.96566391444947 -3.14706309046818 0.155850963946258 -117.900251579912 133.866781330311 -0.880728216576733 0.379127995379004 -454.615467139677 235.102946380106 -1.93368681311492 0.0540360905635274 CYP27A1 other 1 1 1 -0.880728216576733 -1.93368681311492 2.19750817192807e-14 163.868466016961 58.4036551160491 2.80579127609995 0.00532760204881196 -576.935920746921 100.795709161274 -5.72381429276733 2.40292832772499e-08 EIF4E2 other 2.98970986790814e-10 0.000364476168749326 1 2.80579127609995 -5.72381429276733 0.00271271156117552 28.3002847446701 11.7074485573426 2.41728884018209 0.0161970246821328 -22.6792637828061 20.4625677555015 -1.10832931887097 0.268554542952293 ARMC9 other 1 1 1 2.41728884018209 -1.10832931887097 1.23790205228384e-09 391.467252214901 165.380676372968 2.36706766957501 0.018524428163012 -1271.31408880421 288.054092493323 -4.41345609013933 1.39248905353897e-05 CAB39 other 1.49043407094975e-05 0.204347768606844 1 2.36706766957501 -4.41345609013933 0.0657272692388362 148.671662513885 119.991857185507 1.23901459649915 0.216280401323609 -695.821980727089 394.274704594722 -1.76481517231071 0.0785826603796832 COX5B essential 1 1 1 1.23901459649915 -1.76481517231071 0.00379592950874146 58.4904812570492 32.0655814582314 1.82408921332797 0.0690799165535291 -242.333686166886 99.3271815238759 -2.43975196365191 0.0152451404322964 REV1 other 1 1 1 1.82408921332797 -2.43975196365191 0.126338704494249 -1.02096550077277 4.36740876220194 -0.233769165279145 0.815315082196026 -27.9641098417185 13.7362114202229 -2.03579495002158 0.0426021388625383 TSGA10 other 1 1 1 -0.233769165279145 -2.03579495002158 6.84643229052628e-06 56.9787342392161 11.8125233238546 4.82358702514909 2.18493546387856e-06 -18.8605256866522 38.5038885100082 -0.489834310676176 0.624586785608658 MFSD9 other 0.0663419288951997 1 0.0255506353145959 4.82358702514909 -0.489834310676176 1.59199320752513e-08 364.905123517345 68.1304068531937 5.3559803965891 1.67848435307044e-07 -508.423347899757 226.372816711039 -2.24595583200589 0.025422493283643 TMEM127 other 0.000183015539137089 1 0.00207041044951239 5.3559803965891 -2.24595583200589 0.490466667316692 14.0936593434691 11.7957647141033 1.19480675353065 0.233050104989444 7.76839804747475 38.3671129620646 0.20247543919074 0.839674129651866 EDAR other 1 1 1 1.19480675353065 0.20247543919074 0.00114031699551316 90.4055709609787 26.2488557458129 3.44417188453633 0.000649101603418314 -74.7973062516754 83.3223457651154 -0.897686035658766 0.370027848232255 TGFBRAP1 other 1 1 1 3.44417188453633 -0.897686035658766 0.111429791178354 44.2619168124886 23.6854079754103 1.86874200598277 0.062575040508916 -51.3422559264448 77.0395769473633 -0.66644000344815 0.505611589184111 GCC2 other 1 1 1 1.86874200598277 -0.66644000344815 2.28281000831887e-05 87.1819996894427 22.7065918658906 3.83950177130748 0.000148599121971002 -153.747482874528 72.0780561605581 -2.1330692177942 0.0336796172060896 MRPS9 essential 0.21097730096883 1 1 3.83950177130748 -2.1330692177942 9.84753519531923e-07 59.959938667567 12.0468491987445 4.97722995269301 1.05575383673306e-06 -49.4335815568129 38.2405901437479 -1.29269923322287 0.197047683643465 C2orf49 other 0.0102020464623507 1 0.012572972441654 4.97722995269301 -1.29269923322287 0.285649862961719 6.96551768661213 5.55133303769615 1.25474685797321 0.210531297754909 -14.0363823267963 18.4525670810332 -0.7606736919127 0.447439647257657 ANKRD36 other 1 1 1 1.25474685797321 -0.7606736919127 0.00367058919161882 40.6133981956704 20.3945025752969 1.99138949556259 0.0472987098879512 -127.179648888326 53.6605368450218 -2.3700778330943 0.0183844855516895 EPC2 other 1 1 1 1.99138949556259 -2.3700778330943 0.00369105930448372 371.743768005668 123.148342962094 3.01866642347022 0.00274295223865251 -365.812424586018 334.703167520599 -1.09294581015133 0.275239692364931 ARHGEF4 other 1 1 1 3.01866642347022 -1.09294581015133 0.920894017006762 -13.699184645776 50.0958396375309 -0.273459527675286 0.784676409745517 36.0255742340318 140.492889349961 0.256422758480635 0.797789189512788 ISCU essential 1 1 1 -0.273459527675286 0.256422758480635 0.0442028337812695 105.188164272057 42.2667303310638 2.48867521684661 0.0133300790715245 5.2448469844091 108.45680259952 0.04835885678629 0.961460416142262 ALDH1L2 other 1 1 1 2.48867521684661 0.04835885678629 0.000474496452742914 201.019047402833 63.4781149666089 3.16674569666372 0.0016900532613251 -307.784734834726 160.215353145794 -1.92106891625203 0.0556112257439662 SCYL2 other 1 1 1 3.16674569666372 -1.92106891625203 3.65817629276299e-05 939.493171458797 238.802125257174 3.93419099786915 0.000102413545554176 -1154.18312237291 651.689859452742 -1.7710619639565 0.0775022342541875 CKAP4 other 0.331138118020906 1 1 3.93419099786915 -1.7710619639565 0.48633248312276 -16.0273505032807 33.4492242017474 -0.479154625728013 0.6321569251863 81.739051557768 81.373793296565 1.00448864734463 0.315904467358746 PLXNC1 other 1 1 1 -0.479154625728013 1.00448864734463 0.0352822202209133 28.3778868754542 44.257807165944 0.641195049927616 0.521854919644113 -275.140985185558 114.805295119798 -2.3965879352381 0.0171220322890712 APPL2 other 1 1 1 0.641195049927616 -2.3965879352381 7.01659604777842e-09 216.453595557392 38.3313564243969 5.64690675594316 3.60718676214353e-08 -205.63680230005 104.606088634874 -1.9658205844769 0.0501836781255073 PWP1 essential 8.20240077985297e-05 1 0.000456814131557857 5.64690675594316 -1.9658205844769 0.746881718930803 31.4856029302502 52.8186209391151 0.596108008320478 0.55152581149465 -53.4074090488417 135.219748891713 -0.39496752128723 0.693130818506274 DRAM1 other 1 1 1 0.596108008320478 -0.39496752128723 3.98070891224191e-05 170.096350632185 45.4261839319448 3.74445608037458 0.000214326215033978 -237.882732431321 116.563988389125 -2.0407909485492 0.0420919193600549 WASHC4 other 0.359258979329833 1 1 3.74445608037458 -2.0407909485492 0.0933066656497538 24.4000430697731 12.1756761360545 2.00399902207648 0.0459126654514633 -17.4703770107574 30.8976388902551 -0.565427574346706 0.572179194280714 SLC41A2 other 1 1 1 2.00399902207648 -0.565427574346706 0.00093447237130424 -18.5805529456447 28.7726436230361 -0.645771490068037 0.518890147354436 -143.956502009075 41.2150784976758 -3.49281154510462 0.000545216404541277 VILL other 1 1 1 -0.645771490068037 -3.49281154510462 4.06345135770297e-10 3145.62436983937 867.271562889148 3.62703506541864 0.000333517136736182 -3624.35804220374 1251.8207856149 -2.89526910229682 0.00404884278742622 FLNB other 4.9891055769877e-06 1 1 3.62703506541864 -2.89526910229682 3.6422782936726e-07 22.6210074726617 5.53918289903828 4.08381667205631 5.61943001155135e-05 -20.7875407471603 10.3057842365737 -2.01707509782598 0.0445329952660761 NEK3 other 0.00389395972376538 1 0.596221524225598 4.08381667205631 -2.01707509782598 1.12937522223311e-16 214.24125344587 34.5864523847569 6.19436914380648 1.82664315981734e-09 -251.98737465241 64.308110149324 -3.91843849970544 0.000109349747460473 VPS36 other 1.58564281201529e-12 1 2.4140916000146e-05 6.19436914380648 -3.91843849970544 0.000408041531029537 45.6261742858887 24.9072643451308 1.83184205433658 0.067910174104919 -118.558990558013 46.1935487763959 -2.56657030469575 0.0107284102377012 RNASEH2B other 1 1 1 1.83184205433658 -2.56657030469575 2.43930412682894e-10 201.38898342579 54.6491129718638 3.68512812878546 0.000269029879264234 -413.169804068379 101.611496243146 -4.06617183433364 6.04340077706624e-05 CKAP2 other 3.01790706571276e-06 0.869101465749896 1 3.68512812878546 -4.06617183433364 1.47617636093774e-05 260.879969632681 54.3271675274165 4.80201677183017 2.49802202835855e-06 166.087349964901 112.950657081992 1.47044164465849 0.142504353267489 TBC1D4 other 0.138834386746194 1 0.0291269368506607 4.80201677183017 1.47044164465849 2.58255303099867e-16 193.42801109485 33.9273169045392 5.70124692262274 2.73688146228599e-08 -274.935311734877 63.0825505980401 -4.35834171460117 1.77622326029191e-05 THSD1 other 3.61428296688263e-12 0.2598259385155 0.000348487116592875 5.70124692262274 -4.35834171460117 6.73773592591497e-07 58.3467899014106 12.9532257667043 4.50442159754435 9.53288637537018e-06 -46.5528349974705 26.8543264212023 -1.73353203008345 0.0840251629880329 BORA essential 0.00705508328802557 1 0.107216373063788 4.50442159754435 -1.73353203008345 2.00013195529608e-18 125.432531227544 17.8912593634485 7.010827392274 1.4333982830224e-11 -107.892679264818 33.6145370854717 -3.20970296245578 0.00146478735991471 LRCH1 other 2.86318889400633e-14 1 1.9773729314294e-07 7.010827392274 -3.20970296245578 1.13006961392124e-12 223.098972266729 37.7078554410583 5.9165118158326 8.52308328266e-09 -152.02309576413 70.3949828031096 -2.15957288020553 0.0315553426937474 SUCLA2 other 1.48694559799756e-08 1 0.000110322790010751 5.9165118158326 -2.15957288020553 3.76748099322576e-05 55.2925531370254 23.1566955106027 2.38775662579786 0.0175332539206055 -113.876801965387 42.9781047942035 -2.64964689603404 0.00845897617601182 RCBTB1 other 0.340617956597541 1 1 2.38775662579786 -2.64964689603404 1.72545823360344e-16 164.113027503673 27.0717897135025 6.06214178081542 3.81362009217862e-09 -185.349127700629 50.7199724063012 -3.65436176139564 0.000301640132809178 MED4 essential 2.41926498933538e-12 1 4.99469823472634e-05 6.06214178081542 -3.65436176139564 1.76182423761778e-12 35.0970044333716 18.695513273524 1.87729557995473 0.061389986317918 -211.479537233694 34.7742064380812 -6.08150577383421 3.40208669149680e-09 PHF11 other 2.30746120400801e-08 5.18239865715707e-05 1 1.87729557995473 -6.08150577383421 2.50813125878921e-27 158.201364064881 18.9971473741439 8.32763787894814 2.50909942810484e-15 -170.546279926237 35.5656872397243 -4.79524769974777 2.50337417498169e-06 COG3 essential 3.76721315070139e-23 0.0373027785814022 3.62414321395463e-11 8.32763787894814 -4.79524769974777 8.40888995881251e-05 700.357397207191 159.742353300062 4.3842937251064 1.61864495090612e-05 509.166584998833 332.117513028084 1.53309164685868 0.126321365157879 LMO7 other 0.730059826224102 1 0.179038318019726 4.3842937251064 1.53309164685868 0.0425012379195072 303.099421514828 190.336724649854 1.59243793898636 0.112360892998314 -568.872990298373 389.725548700493 -1.45967589806527 0.145446834233542 SCEL other 1 1 1 1.59243793898636 -1.45967589806527 3.05898005247805e-14 3342.73746312974 579.601707116837 5.76730092766256 1.90854005010172e-08 -3369.23647537412 1084.25732137827 -3.10741408791344 0.00205761604853274 ITM2B other 4.14797695116024e-10 1 0.000244655749022539 5.76730092766256 -3.10741408791344 0.0924191152002364 75.1419037861945 34.4656968209748 2.18019395274391 0.0300442258711008 28.7573023087634 69.1807410988841 0.415683640446392 0.67794787518911 SPRY2 other 1 1 1 2.18019395274391 0.415683640446392 1.11473065562595e-15 171.502708377072 29.2821324529883 5.85690637976639 1.17952400680517e-08 -196.649252671886 54.8611290842165 -3.5844915326116 0.000390891908253625 NUDT15 other 1.5479149884022e-11 1 0.000152028849237118 5.85690637976639 -3.5844915326116 0.654623486231503 -7.00891500789928 8.58996444442103 -0.81594226067506 0.4151937324145 -11.1128970996902 17.5884533716667 -0.631829124759316 0.527989523355458 EDNRB other 1 1 1 -0.81594226067506 -0.631829124759316 8.53118844833897e-06 43.1356886744887 14.4048679535584 2.99452163071255 0.00296518436358537 -63.9337398140211 26.8734290172263 -2.37906892243035 0.0179481279857695 RCBTB2 other 0.0819164714809508 1 1 2.99452163071255 -2.37906892243035 0.272605882755953 -392.355387754163 257.416333397677 -1.52420548679024 0.128454374336016 -537.201269706084 482.962603996558 -1.11230406921922 0.266850247470301 LCP1 other 1 1 1 -1.52420548679024 -1.11230406921922 0.0423075827814592 9.02338837703302 8.20256210466613 1.10006949802915 0.272133900607394 -25.205459016974 15.2480467881242 -1.65302870375536 0.0993118883629325 SETDB2 other 1 1 1 1.10006949802915 -1.65302870375536 3.12460522348037e-09 447.629272856128 80.7600190484235 5.54270885681355 6.27429090268529e-08 -709.488968654991 327.132606944725 -2.16881152655893 0.0308401741737724 SCRN1 other 3.7076565581818e-05 1 0.000787486251196031 5.54270885681355 -2.16881152655893 1.17017474996879e-11 60.2651797716644 8.6394899894056 6.97554830731515 1.75573343014323e-11 -37.718575458659 35.1330422056747 -1.07359263788909 0.283814198864794 C7orf25 other 1.50227034400993e-07 1 2.41782050665024e-07 6.97554830731515 -1.07359263788909 0.00355301869640524 175.605803542725 60.7788980635361 2.88925612568942 0.00412588188330904 -476.376822397609 349.546644134516 -1.36284192794105 0.173893588691463 TNS3 other 1 1 1 2.88925612568942 -1.36284192794105 0.014874585671012 148.050925025117 51.0046170362472 2.90269653274531 0.00395731048778481 180.986012888586 212.860854687865 0.850255032349564 0.395821020690608 IGF2BP3 other 1 1 1 2.90269653274531 0.850255032349564 0.00420524306460731 3619.63749645446 1198.57405071228 3.0199531637644 0.00273230287598274 -4187.60709640992 5002.08631426445 -0.837172098463818 0.403122575308282 GPNMB other 1 1 1 3.0199531637644 -0.837172098463818 0.0147669832548931 87.281105637812 33.6169518685448 2.5963420472836 0.00985691046502239 -119.796701284247 142.192778053913 -0.842494977057319 0.400140185816125 RAPGEF5 other 1 1 1 2.5963420472836 -0.842494977057319 3.42859220349729e-08 909.928237157523 171.715591951604 5.29904260187378 2.1758912654377e-07 -1669.07777809078 821.947350717706 -2.03063830868654 0.0431208312201049 RAC1 essential 0.000387705206371473 1 0.00267308241959022 5.29904260187378 -2.03063830868654 5.28512965685304e-21 1473.65892232781 144.412851236635 10.2044860253682 2.45459298615663e-21 -359.207945506152 690.84224789865 -0.519956540872771 0.603455627381402 KDELR2 other 7.72315996755935e-17 1 3.66421640973462e-17 10.2044860253682 -0.519956540872771 0.000210368472050606 47.2092409730857 12.3796492836109 3.81345544542888 0.00016450005773148 -49.3509645232523 51.6647880205183 -0.955214690973917 0.340192431268532 NUPL2 other 1 1 1 3.81345544542888 -0.955214690973917 0.0905276813208686 -15.8559617334579 60.9509460063676 -0.260142996497567 0.794920777018754 541.322807121258 257.809939805069 2.0996971937178 0.0365382513647459 IL6 other 1 1 1 -0.260142996497567 2.0996971937178 8.25838943359243e-18 204.634598692233 22.0464829817762 9.28196115731412 2.66665296615564e-18 -34.4891606920208 105.465972944698 -0.327016948965194 0.743870214941411 ZDHHC4 other 1.1751688164002e-13 1 3.92611316207094e-14 9.28196115731412 -0.327016948965194 0.0518055725445275 -28.3662672306846 11.6094768050155 -2.44337171322224 0.015092493010199 -16.1683350509909 47.334596485276 -0.341575427943498 0.732895326704493 AOAH other 1 1 1 -2.44337171322224 -0.341575427943498 5.96705833999759e-17 536.067404724481 62.6830703006796 8.55202851668018 5.12728616140256e-16 -462.075965772081 266.734747577072 -1.73234259866561 0.0841791431293211 BZW2 other 8.4034082602186e-13 1 7.44174313465967e-12 8.55202851668018 -1.73234259866561 1.45520363638981e-15 423.486497361606 49.5219309216851 8.55149404475596 5.09433103384317e-16 -18.0367758746597 198.596751742282 -0.0908211021400083 0.927691564980688 TBRG4 other 2.01807640294539e-11 1 7.39442149562336e-12 8.55149404475596 -0.0908211021400083 4.39701990097926e-15 401.25936793185 48.279422030116 8.31118830879024 2.73434197851707e-15 -92.045186292504 193.613944624629 -0.475405769305293 0.634822126606562 DDX56 essential 6.05205819170785e-11 1 3.9486632511765e-11 8.31118830879024 -0.475405769305293 6.88311215168176e-40 126.977000685827 8.30965661758186 15.2806555709131 6.13352074994251e-40 -42.913956846482 47.7898197751057 -0.897972770109427 0.369877307546329 HUS1 essential 1.0510512255618e-35 1 9.37447311421214e-36 15.2806555709131 -0.897972770109427 0.000221384212012103 40.3103314070326 9.89804317014041 4.07255562681697 5.86718409894867e-05 -1.85888003246547 39.6939130928355 -0.0468303547729837 0.962677648012638 NACAD other 1 1 0.621745498965591 4.07255562681697 -0.0468303547729837 0.00143323848318565 312.044838939323 92.5019909919942 3.37338510871977 0.000833706332443369 -276.182414299489 370.958777228528 -0.744509717125112 0.457114551506121 CCM2 other 1 1 1 3.37338510871977 -0.744509717125112 0.345137617448576 26.1827536280064 40.6937824274006 0.643409190942562 0.520419432229415 -190.275630480414 163.193414630165 -1.16595164646579 0.244502269005699 MYO1G other 1 1 1 0.643409190942562 -1.16595164646579 1.3872312651155e-15 1066.46858178958 127.621773134036 8.35647833124457 2.05422989816728e-15 -565.11117616218 581.511585371783 -0.97179693470919 0.33189250209394 TTYH3 other 1.92422848784171e-11 1 2.97000558677025e-11 8.35647833124457 -0.97179693470919 5.92590967443526e-15 123.605042909495 28.3149529859496 4.36536281627698 1.71536133970225e-05 -465.7199950986 77.0938641630593 -6.04094761826398 4.25260637685067e-09 CIDEB other 8.14219989267404e-11 6.4758689906682e-05 0.189383949689233 4.36536281627698 -6.04094761826398 9.50945823215018e-13 86.5099980237341 11.2967427644699 7.65795945144664 2.2590007647942e-13 3.46870613497822 33.4951982302646 0.103558310392206 0.917584743727757 TTC5 other 1.25372697332668e-08 1 3.1964860821838e-09 7.65795945144664 0.103558310392206 7.82542771723802e-15 24.4480003391625 2.89888765115068 8.43357980067224 1.30195233221235e-15 8.38900499994135 9.33907193851686 0.898269662678454 0.369741194717008 NKX2-8 other 1.07325741141919e-10 1 1.88509678181026e-11 8.43357980067224 0.898269662678454 0.700479018143834 -3.63207524610418 4.43465424250095 -0.819021066241199 0.413383925332739 -4.82687617073853 12.1602260155439 -0.396939675674493 0.691676546283179 ZFHX2 other 1 1 1 -0.819021066241199 -0.396939675674493 0.000593408321961403 33.7293302339826 16.8483985128333 2.00193093772629 0.0461385240217255 -79.2865505095869 32.9650079285456 -2.40517310602343 0.0167339394997261 MTHFS other 1 1 1 2.00193093772629 -2.40517310602343 0.0115548671779154 83.2963101313595 28.1318898486118 2.96092123848088 0.00329650303490612 86.7499194942432 54.7465621323921 1.58457291408469 0.114051115896524 ADAMTS7 other 1 1 1 2.96092123848088 1.58457291408469 0.0133370199823615 89.2209297073325 93.5268569526078 0.953960526574124 0.34082592764549 -418.137092232968 184.076651637264 -2.27153790833254 0.0237802020836549 ABHD17C other 1 1 1 0.953960526574124 -2.27153790833254 7.52885865102174e-06 168.549476894664 50.5200918025131 3.33628603751428 0.00094897744884913 -211.549365471698 97.6584579835285 -2.16621652481323 0.0310326242177634 IREB2 other 0.0726911302756149 1 1 3.33628603751428 -2.16621652481323 0.252679807022174 139.342972150314 84.4703957577848 1.64960718959899 0.100004529396796 116.840936152574 165.527702423005 0.705869376800674 0.480782926788464 ALPK3 other 1 1 1 1.64960718959899 0.705869376800674 0.890088101010062 -1.20117292355415 5.30864695118565 -0.226267245608767 0.821140322110804 -5.00555614149302 10.4711611387553 -0.478032576823474 0.632958589629912 TM6SF1 other 1 1 1 -0.226267245608767 -0.478032576823474 0.0081418554149919 63.4718240819485 24.1919880922175 2.62367126835546 0.00911556822930909 -27.9362317388727 46.9349267797563 -0.595212002139993 0.552122444927491 CIB2 other 1 1 1 2.62367126835546 -0.595212002139993 0.0557711154859439 88.9988014479908 60.4065091834613 1.47333131232085 0.141650857371042 -261.730875278793 144.075960020043 -1.81661725691353 0.0702170729180815 CALCOCO2 other 1 1 1 1.47333131232085 -1.81661725691353 0.0797715692032978 40.8282448042421 18.1097872352516 2.25448506235169 0.0248436898559814 1.11107204761753 43.6839817036044 0.0254343126310268 0.979724445423763 RSAD1 other 1 1 1 2.25448506235169 0.0254343126310268 3.32477119699979e-08 354.560668526116 72.9930947449967 4.85745493823468 1.86666873252264e-06 -558.294521384037 177.260578398212 -3.14956955702716 0.00178989670957675 NMT1 essential 0.000376264356364466 1 0.0219072242448857 4.85745493823468 -3.14956955702716 0.101344969739152 140.378091341856 119.637036846521 1.17336650122774 0.241529732838209 -452.981103071277 279.979277118958 -1.61790939576865 0.106676670768799 SRSF1 essential 1 1 1 1.17336650122774 -1.61790939576865 0.044654019597992 103.081705196053 44.1492313983328 2.3348471067595 0.0201753302748281 -59.5222088159869 103.319759650352 -0.576097050723096 0.564958362310608 VEZF1 other 1 1 1 2.3348471067595 -0.576097050723096 0.696848737742888 -4.72209827219427 7.59157465895658 -0.622018287948089 0.534374152687609 -11.1862112800291 18.1075288671006 -0.617765757112958 0.537170515051001 CHAD other 1 1 1 -0.622018287948089 -0.617765757112958 4.7155629815376e-06 109.365059557572 21.8624350852795 5.00241894971757 9.36875304450463e-07 -4.57070334656832 50.4146893453302 -0.0906621345072652 0.927817959159252 TACO1 other 0.04633983741957 1 0.0111844173845296 5.00241894971757 -0.0906621345072652 1.31725941977872e-06 198.582536194047 45.4859787228865 4.36579670856086 1.71527895742445e-05 -262.110774196612 104.903810280426 -2.49858202000428 0.0129734602944569 TEX2 other 0.0135216679440286 1 0.189383949689233 4.36579670856086 -2.49858202000428 0.00320309150820853 232.144195500095 97.2448405917522 2.38721349212417 0.0175587123377551 -481.963991302703 224.246220045742 -2.14926249907085 0.032365548617504 DCAF7 other 1 1 1 2.38721349212417 -2.14926249907085 0.594222871651833 44.9727831348082 45.7988554903602 0.981963034955625 0.326862209601253 41.6484023444884 105.61198068338 0.394353008768471 0.693583935704708 LIMD2 other 1 1 1 0.981963034955625 0.394353008768471 0.0778198378070993 -23.5472432468242 21.6256658619046 -1.08885633382067 0.277054894823088 -104.244179819695 49.6452660350723 -2.09978086825138 0.0365483769813622 BRIP1 other 1 1 1 -1.08885633382067 -2.09978086825138 0.000567146133673216 124.847351216729 33.7799557521547 3.69590037751204 0.000257811729987904 -84.4929175530538 80.5724176327329 -1.04865808964789 0.295129350082492 KAT7 other 1 1 1 3.69590037751204 -1.04865808964789 0.644424847864397 14.2502291511807 15.9190644723794 0.895167500320498 0.371372496803312 23.1982644238894 98.7258606409525 0.234976573243126 0.814377676359634 RTP4 other 1 1 1 0.895167500320498 0.234976573243126 3.23919669972866e-27 534.656978793894 43.8684901863853 12.1877223611363 3.51014311012777e-28 96.8917609409687 294.297164484564 0.329231037990686 0.742203387494755 ACTL6A essential 4.86397776431255e-23 1 5.31751579753256e-24 12.1877223611363 0.329231037990686 2.55365413793845e-15 344.027950498674 39.7135982256013 8.66272425239213 2.58585694886209e-16 -122.025096066547 266.423560501313 -0.458011655714455 0.647264943830639 NDUFB5 other 3.52838392238956e-11 1 3.7613875178148e-12 8.66272425239213 -0.458011655714455 1.07794029583003e-14 223.810008752502 26.6769549595011 8.38963851355123 1.74825107843329e-15 108.716957259745 178.965634976427 0.607473928020121 0.543981156395829 MRPL47 other 1.47548467693214e-10 1 2.52832070963023e-11 8.38963851355123 0.607473928020121 8.24055250002473e-11 422.909636439505 59.8051688473218 7.07145627360674 9.8388788700377e-12 -196.482707032104 370.820044165827 -0.529859995767218 0.596579910336391 TRA2B essential 1.0336125000781e-06 1 1.36130728045842e-07 7.07145627360674 -0.529859995767218 0.0460333245548848 32.9307741987567 15.5049633656974 2.12388597264354 0.0344586160649802 -40.2532335167051 43.960664055101 -0.915664819490694 0.360543156034953 SCN2A other 1 1 1 2.12388597264354 -0.915664819490694 7.22544709075388e-11 409.683270363014 69.8438672799331 5.86570140397596 1.1154316771969e-08 -535.74491390344 191.296261945352 -2.80060315060671 0.00541088775328683 MARCH7 other 9.08094190365947e-07 1 0.000143879532041628 5.86570140397596 -2.80060315060671 0.0994000035135612 18.1810939358338 74.3497286681424 0.24453477183467 0.806973397438663 -403.877178808085 195.18101320311 -2.06924419634917 0.039325636108846 GALNT5 other 1 1 1 0.24453477183467 -2.06924419634917 0.00061745153973133 69.4963972456482 25.7754478087597 2.69622463055831 0.00738525184669977 -157.884327359715 70.3256321982096 -2.24504668389933 0.0254499153633182 TANK other 1 1 1 2.69622463055831 -2.24504668389933 3.57239994147471e-05 6.01755888519229 7.14901849288824 0.841732175008148 0.400568450922474 -40.3349230573852 13.7839378917169 -2.92622640744947 0.00367725327414628 BLK other 0.323659434697609 1 1 0.841732175008148 -2.92622640744947 0.364969709997388 9.7408383600868 8.08344024839774 1.20503622971885 0.22908250022817 3.03409147336355 15.5855854123415 0.194672923287244 0.845772931321834 GATA4 other 1 1 1 1.20503622971885 0.194672923287244 1.06376211488855e-11 361.508743097554 49.0402382421802 7.37167591462912 1.47759092712404e-12 -288.047631569061 353.220208330136 -0.815490237466364 0.415404042757217 SKIL other 1.36714707005477e-07 1 2.06995712980807e-08 7.37167591462912 -0.815490237466364 1.54513350829166e-06 571.914575043842 108.314863116449 5.28011169094103 2.39305824898504e-07 -139.577539333825 352.635116410102 -0.395812931947202 0.692507626369503 EPRS essential 0.0157680874521163 1 0.00293412871908055 5.28011169094103 -0.395812931947202 0.340172419675483 11.6727262441305 8.05849956690496 1.44849871210127 0.148459821636549 5.23392097226229 26.2356416386841 0.19949658728929 0.842001415765214 HLX other 1 1 1 1.44849871210127 0.19949658728929 1.81493632951495e-09 120.61758445291 18.4336669345834 6.54333100847232 2.4354100527759e-10 -37.0259083226615 76.3336925532695 -0.485053284915085 0.627975697735596 VPS45 other 2.17138982463168e-05 1 3.28366337415774e-06 6.54333100847232 -0.485053284915085 0.394589039594546 -0.995168395623137 1.10496101878894 -0.900636654778881 0.368458838108962 -3.90813635861243 3.75248292780387 -1.04148011697941 0.298438983348061 IL10 other 1 1 1 -0.900636654778881 -1.04148011697941 0.0368148158976092 156.680283036402 61.5474641681721 2.54568218453793 0.0113766156149403 -80.6371416686582 197.759657211899 -0.407753243535691 0.683728360431634 KCTD3 other 1 1 1 2.54568218453793 -0.407753243535691 0.0279470429680789 60.4682991343381 23.1440887542983 2.61268869888463 0.00940859786033812 -45.3225793523568 74.1316050406808 -0.611379981958915 0.541383481124976 RPS6KC1 other 1 1 1 2.61268869888463 -0.611379981958915 0.0555555695559448 42.0564042419448 17.9743423495264 2.33980211482135 0.0199084228853492 -13.5109321789834 58.6725889599752 -0.230276734306035 0.818023877260226 CBWD2 other 1 1 1 2.33980211482135 -0.230276734306035 0.228944065543096 249.58396120245 146.224268165128 1.70685731126793 0.0888186536115332 20.7394687865672 477.456286052513 0.0434374190735572 0.96537994119567 IL36G other 1 1 1 1.70685731126793 0.0434374190735572 0.699088988187835 456.084080610746 624.241572178511 0.730621126399961 0.465545183478735 -633.118863024893 2038.2940970876 -0.310612126056549 0.756297723555858 IL1RN other 1 1 1 0.730621126399961 -0.310612126056549 0.298469660142214 55.8926261864737 38.1498175216963 1.46508239927195 0.143880235869218 -37.2464665289958 124.56803796016 -0.299005002719142 0.765130317631336 IL36A other 1 1 1 1.46508239927195 -0.299005002719142 0.0139834247393076 658.351271113027 234.323725588217 2.80958007756314 0.00526584351413772 989.244673063201 765.121529806499 1.292924894315 0.196969711605581 IL36RN other 1 1 1 2.80958007756314 1.292924894315 5.3063820692593e-05 27.3416965967856 6.08708325967366 4.49175663127884 9.87744578526474e-06 20.785073910874 19.8757443106104 1.04575071937196 0.296465418366922 IL36B other 0.472002685060615 1 0.110916401603416 4.49175663127884 1.04575071937196 0.00635727586047973 6.89832344507764 5.4508485095971 1.26555038778495 0.206594768159182 55.2601420308357 17.798289694896 3.10480068467941 0.0020742397920929 IL1F10 other 1 1 1 1.26555038778495 3.10480068467941 5.45634620010457e-07 378.100207876925 85.1546623999748 4.44015861516747 1.23926748554647e-05 -613.799571997508 231.381607483835 -2.65275869881054 0.00838183078039979 SMPD4 other 0.00575426270263028 1 0.138141146613866 4.44015861516747 -2.65275869881054 1.76945081800049e-06 166.520260130065 45.6986139181253 3.64387988721947 0.000313680966341474 -406.740995497751 128.52382546874 -3.16471279946986 0.0017029887132386 WDR33 essential 0.0179440007453429 1 1 3.64387988721947 -3.16471279946986 5.14611142882095e-05 108.43898993234 31.0251945994812 3.49519128992517 0.000540556519288787 -196.072874356475 83.648783979815 -2.34400149084999 0.0196895245024899 CCDC115 essential 0.458775833879388 1 1 3.49519128992517 -2.34400149084999 5.48185946050526e-08 161.195284347833 30.8390689384541 5.226982846646 3.12650027505089e-07 -169.476713597484 86.7602952955664 -1.95339023478571 0.05165002206116 SAP130 essential 0.000613036343468303 1 0.00381401768553458 5.226982846646 -1.95339023478571 0.139874683412028 284.575290102323 156.083519027661 1.82322446261538 0.0692110798565646 496.563158202277 456.63111374101 1.08744924132331 0.277664446664393 BIN1 other 1 1 1 1.82322446261538 1.08744924132331 7.93152291459523e-08 269.546509293795 48.9759093958408 5.50365501363586 7.63594570315882e-08 -165.363532775382 132.046722612215 -1.25231076927982 0.211371124735295 IMP4 essential 0.000879923152145195 1 0.000955638604750326 5.50365501363586 -1.25231076927982 0.00768011544912816 219.386268618702 116.261103830088 1.88701346702616 0.0600663390208525 -702.564988350048 322.782977814679 -2.17658624102978 0.0302445668016066 HS6ST1 other 1 1 1 1.88701346702616 -2.17658624102978 3.88017262901401e-06 361.791881668964 89.5213943703307 4.04140132326703 6.66942449717451e-05 -608.683421279973 251.852694591437 -2.41682314444718 0.0162191519020373 UGGT1 other 0.0383710271283195 1 0.703824367186826 4.04140132326703 -2.41682314444718 0.294888920165019 -32.8805805303361 25.3492663438383 -1.29710186024095 0.195539387732709 48.2146891302393 74.1607044434528 0.650137960420841 0.516073982859052 GYPC other 1 1 1 -1.29710186024095 0.650137960420841 4.00694294683103e-18 181.437317516511 28.5710378028367 6.350392966772 7.35989575821673e-10 -164.904794436935 57.0784268763193 -2.88909143894697 0.00412714745133344 STAM other 5.71910966801193e-14 1 9.83282073297754e-06 6.350392966772 -2.88909143894697 8.49113634773251e-17 540.333925459178 90.8109556692072 5.95009623538625 7.0693082876767e-09 -572.688880882155 181.175248608563 -3.16096644150037 0.00172386781428936 ABI1 other 1.19376885912771e-12 1 9.17949681154819e-05 5.95009623538625 -3.16096644150037 3.63270516679698e-22 701.142756630048 110.656949132867 6.33618369315587 8.07431259750157e-10 -1001.54050455236 218.034819066224 -4.59348882367344 6.29754471820972e-06 YME1L1 other 5.34625219397512e-18 0.093178471650631 1.07743627301061e-05 6.33618369315587 -4.59348882367344 3.72421575424266e-08 5.20845313133932 24.8420307251492 0.209662937340564 0.834064172057985 -247.482136329225 49.4334748382488 -5.00636738847534 9.17862625095086e-07 DNAJC1 other 0.000420314990023827 0.0137615143380506 1 0.209662937340564 -5.00636738847534 3.11182156031311e-05 49.5404151854836 21.3585340295118 2.31946701571522 0.020998880305377 -159.919147581594 42.6617703221446 -3.74853519612579 0.00021101586819127 NIPSNAP3A other 0.283829244516159 1 1 2.31946701571522 -3.74853519612579 5.09262089505734e-09 1815.91238609199 296.254835875252 6.12956200605834 2.59053379062022e-09 -561.074718135557 578.689318129161 -0.96956121455542 0.33299749881469 LRRC8A other 5.99299626930348e-05 1 3.4099196285934e-05 6.12956200605834 -0.96956121455542 0.000169652265399027 1662.66131242498 415.52759937769 4.00132582027053 7.83099378568915e-05 -815.443685345362 829.754648412658 -0.98275277746901 0.326471561424017 TXN essential 1 1 0.820609838802366 4.00132582027053 -0.98275277746901 1.3796142821361e-13 271.863965931179 36.9197096080961 7.36365396199005 1.52727667079167e-12 -170.875632134328 72.1171065968092 -2.36941885494181 0.0184091417666554 ODF2 other 1.84909702234702e-09 1 2.13879824977665e-08 7.36365396199005 -2.36941885494181 1.81270986613175e-12 481.391416331028 70.595287007377 6.81903051517765 4.57953371173509e-11 -406.767485748194 140.969619438332 -2.88549750910079 0.00417333491854788 KIAA0368 other 2.37301848575308e-08 1 6.25839077045718e-07 6.81903051517765 -2.88549750910079 7.33735700668694e-10 140.506794944417 21.7615026397655 6.45666787217462 3.97023284605189e-10 -44.9909592123912 42.6087102220944 -1.05590990616425 0.291805899830239 TOR1B other 8.91780105475765e-06 1 5.3328167588169e-06 6.45666787217462 -1.05590990616425 1.48296355427233e-11 277.375833989075 40.7341692985443 6.80941427714317 4.85494832614361e-11 -156.150946191524 79.7569195707944 -1.95783572173848 0.0511180324997433 C9orf78 essential 1.89834164582401e-07 1 6.63137391867956e-07 6.80941427714317 -1.95783572173848 6.08713730247656e-06 185.795906360315 61.4148872353198 3.02525844667616 0.00268550882513422 -446.777915402242 122.670769912083 -3.64208943762597 0.000315335651159907 SMC2 essential 0.059215671678492 1 1 3.02525844667616 -3.64208943762597 0.396135158953558 384.212827440475 284.766166394144 1.3492221786934 0.178219471879543 182.500427310435 570.036228644256 0.320155839470913 0.749059140781968 KLF4 other 1 1 1 1.3492221786934 0.320155839470913 2.23903024885166e-10 182.720174397592 27.1214097799697 6.73711934150779 7.51714390981358e-11 -38.7454548716751 53.1033315694717 -0.729623805636127 0.466153898334087 TOR1A other 2.77438238135209e-06 1 1.02353431476022e-06 6.73711934150779 -0.729623805636127 0.00345456588017871 -24.8583203578199 15.3510308329829 -1.61932580477982 0.106362261695922 -94.9834913733962 30.05709831718 -3.16010182922767 0.00172786105955025 RALGPS1 other 1 1 1 -1.61932580477982 -3.16010182922767 1.44062179392645e-09 2466.56022303301 534.512489333199 4.61459792288489 5.7073571426686e-06 -4285.5946004223 1047.04364644253 -4.09304293568199 5.39554282034166e-05 FAM129B other 1.73047489886445e-05 0.777605631267641 0.0651266523549914 4.61459792288489 -4.09304293568199 0.0196097620600047 48.7922478586391 21.2094378569326 2.30049698571764 0.0220629219211241 -55.7845016985719 41.5277752910402 -1.3433058069597 0.180124832597215 ST6GALNAC4 other 1 1 1 2.30049698571764 -1.3433058069597 0.3161850802447 51.7934919349442 48.6277949243264 1.06510056677553 0.287633415320685 112.606622608045 93.0903948899976 1.20964813546134 0.227306816126715 TMOD1 other 1 1 1 1.06510056677553 1.20964813546134 6.01794264084032e-12 830.549275091843 127.697972363755 6.50401302164749 3.00854959419462e-10 -733.916887587985 254.698936619953 -2.88150746653133 0.00422516456223352 DAB2IP other 7.7866159829833e-08 1 4.05071117362364e-06 6.50401302164749 -2.88150746653133 0.00281005317140209 154.703103186845 44.9805625816944 3.43933233173485 0.000660392580699825 5.17722673957509 88.1113410901332 0.0587577793678008 0.953181712654713 STXBP1 other 1 1 1 3.43933233173485 0.0587577793678008 0.0113598104150055 34.9119709348091 17.9594235610318 1.94393605207691 0.0527794196741889 -71.8744591572694 35.1802824229735 -2.04303246611612 0.0418681476258031 SLC2A8 other 1 1 1 1.94393605207691 -2.04303246611612 0.189934016395861 79.2412955173539 107.757858034732 0.735364426896955 0.462656192092669 369.145216563253 210.988341345758 1.74960006893611 0.0811459319481137 ANGPTL2 other 1 1 1 0.735364426896955 1.74960006893611 1.29769759586484e-05 241.455393773125 66.0587547342283 3.65516114774738 0.000300595304546483 -357.962673982533 132.156487168362 -2.70862733757824 0.00712201955935285 CDK5RAP2 other 0.122684330713062 1 1 3.65516114774738 -2.70862733757824 0.452220138004651 3.82289319513299 3.94139624038757 0.969933739713789 0.332812055506926 -5.64345801412047 7.88776742130241 -0.715469626916134 0.474840606723816 ZFP37 other 1 1 1 0.969933739713789 -0.715469626916134 5.23498806130137e-10 303.125152058722 47.7886785341184 6.34303272986106 7.67919818078572e-10 -168.393057187825 95.6376772743475 -1.76073972086096 0.0792376278519582 SLC31A2 other 6.40134340135932e-06 1 1.02532654109851e-05 6.34303272986106 -1.76073972086096 2.69315701877849e-07 249.042068352053 47.1035741442819 5.28711616637025 2.30612531714121e-07 -137.417992608892 94.2666037367597 -1.45775902771073 0.145887649864361 SLC31A1 other 0.00290241531913758 1 0.00283007698919569 5.28711616637025 -1.45775902771073 0.416464174112194 -13.6430468370961 12.6572927442529 -1.07788032660387 0.281901565511939 16.2307588745454 25.3012309129203 0.641500760591734 0.521658036219916 TLR4 other 1 1 1 -1.07788032660387 0.641500760591734 0.0136439377658711 33.1361052317379 13.8979781474241 2.38423926705336 0.0176968659691205 -37.840361445783 26.5966893271265 -1.42274705623564 0.155783588925909 ZNF189 other 1 1 1 2.38423926705336 -1.42274705623564 1.89954295203478e-05 60.031915348287 13.6114625255082 4.41039419796261 1.41250974178238e-05 -30.5128466310983 26.0705110206959 -1.1703969518233 0.242714874878571 STX17 other 0.176676489968755 1 0.156802706435263 4.41039419796261 -1.1703969518233 4.58034493406331e-12 423.953538513199 58.8126391443062 7.20854470538145 4.09732139920856e-12 -178.984045247964 117.699513246011 -1.52068636744367 0.129326019078604 PRPF4 essential 5.94391362093396e-08 1 5.70224219127855e-08 7.20854470538145 -1.52068636744367 1.17541013628982e-08 319.017077362895 58.5521566168568 5.44842574203411 1.01556833827821e-07 -265.81273173501 114.644283322947 -2.31858688484475 0.0210472351817908 FPGS other 0.000135924428160555 1 0.00126417946748871 5.44842574203411 -2.31858688484475 1.85544771335877e-08 93.1769576096933 20.4034012945936 4.56673650948495 7.07712934411233e-06 -141.696742231126 40.0978694322871 -3.5337723484388 0.000470023314956677 USP20 other 0.000212875516153652 1 0.0802900324089544 4.56673650948495 -3.5337723484388 0.00583483604739669 31.6192807737362 10.4044696818589 3.03900936237694 0.00256922115351578 -17.0590159893878 20.8771397764224 -0.81711461302057 0.414470857546356 KIF12 other 1 1 1 3.03900936237694 -0.81711461302057 3.11414706769366e-05 328.608878870114 73.5216624033334 4.4695518045742 1.08931626975749e-05 -119.337085800269 147.911936711115 -0.80681173172213 0.420374192548198 ATP6V1G1 essential 0.284010212573661 1 0.12186181109777 4.4695518045742 -0.80681173172213 1.80265616912634e-11 163.096181242948 26.675909356655 6.11398768313252 2.83624572482741e-09 -163.825373925155 51.0933037185725 -3.20639618114192 0.0014803017688324 TEX10 essential 2.30415511537728e-07 1 3.7288122544306e-05 6.11398768313252 -3.20639618114192 0.0153587714649071 7.28047916955718 4.26755389899421 1.70600754949412 0.0889769521728062 -17.7691788277535 8.35960858719527 -2.12559937973306 0.0343022193259745 GARNL3 other 1 1 1 1.70600754949412 -2.12559937973306 1.96755835149444e-08 94.8269198415284 18.5735354673159 5.10548570617568 5.67433761103005e-07 -96.4512048192774 35.5443466157793 -2.71354558467139 0.00701725784699731 MRPL50 essential 0.000225482187081263 1 0.00684211629138003 5.10548570617568 -2.71354558467139 1.20090808185047e-11 334.829417932413 49.0200832297155 6.83045388485678 4.27226913324542e-11 -188.050253149142 95.7105774075489 -1.96478025984942 0.050304591665355 DPM2 other 1.54160570467144e-07 1 5.84104635897314e-07 6.83045388485678 -1.96478025984942 0.649638996897226 -5.42614039507411 9.30939553043291 -0.582867102094413 0.560397155819863 11.8356602216759 18.2922634791529 0.647030928412143 0.518080164395856 WDR38 other 1 1 1 -0.582867102094413 0.647030928412143 0.00448050864933015 65.8364488192445 22.3300491393059 2.94833425616415 0.00342998979064748 -48.6457600329814 42.7474265597668 -1.13798101892679 0.255979702433848 TSTD2 other 1 1 1 2.94833425616415 -1.13798101892679 3.084983941593e-08 894.438047854365 169.364330488144 5.28114772028091 2.38064778027258e-07 -748.143017409903 333.018400029895 -2.24655159397421 0.0253524018027798 PSMB7 essential 0.00034980632913723 1 0.00291915030817024 5.28114772028091 -2.24655159397421 0.29432211444325 -28.4986120032266 41.0923885353225 -0.693525322304628 0.48848460204278 -119.727336922006 80.7993126061325 -1.48178657788382 0.139384205564942 NR5A1 other 1 1 1 -0.693525322304628 -1.48178657788382 4.23767003000672e-09 31.4249351820477 7.09751407036982 4.42759744756804 1.30921493884452e-05 -54.785244676552 13.5870933192884 -4.03215341126555 6.91464259653871e-05 TRMO other 5.00595960644694e-05 0.992596944733132 0.145728714842783 4.42759744756804 -4.03215341126555 1.44653979108848e-07 99.2192002281912 17.9981002387864 5.51275961972759 7.31502520520276e-08 -34.3817206971459 35.3443781870808 -0.972763490565898 0.331410208480734 RABEPK other 0.00158247084979805 1 0.000916206906951645 5.51275961972759 -0.972763490565898 2.83843338308973e-10 101.484098421506 17.3169907259387 5.86037724611673 1.15749560140228e-08 -96.4440744271524 34.0265870098 -2.83437402638635 0.00488618685241995 GOLGA1 other 3.5042034608858e-06 1 0.000149224332932782 5.86037724611673 -2.83437402638635 0.260864679349807 26.8453071367461 17.3960164328539 1.54318704172102 0.123773707225244 -12.1761351367962 33.301983809205 -0.365627921944716 0.714884306865119 XPA ts 1 1 1 1.54318704172102 -0.365627921944716 3.20482964460658e-12 179.663274069392 32.2086978690518 5.57809802804926 5.18098156335978e-08 -271.507645989282 61.6585721846648 -4.4034046908535 1.45473965878361e-05 NCBP1 essential 4.17204723134885e-08 0.213337570960617 0.000652389198458263 5.57809802804926 -4.4034046908535 2.57909328835984e-10 897.713573413077 158.112568064871 5.67768637496774 3.06445600330933e-08 -949.831980479588 300.731798910132 -3.15840221726412 0.00173765765806478 ANP32B other 3.18853303239927e-06 1 0.000389339135220451 5.67768637496774 -3.15840221726412 3.25084640858159e-07 59.0909744081231 13.2596065563199 4.45646514149084 1.15379394475693e-05 -73.6181754469754 26.4999408930119 -2.77805055279911 0.00579140326838368 PDCL other 0.00348653277320375 1 0.128832631871558 4.45646514149084 -2.77805055279911 2.55049091059486e-05 2553.23781125476 647.8905527816 3.94084741673249 9.99294043299781e-05 -2567.3430851001 1273.05630729646 -2.01667677257125 0.0445721437243863 RPL35 essential 0.23456864904741 1 1 3.94084741673249 -2.01667677257125 0.00740321975161794 643.515707509635 204.202484264658 3.15136081633367 0.00177879358895238 224.320149014663 390.914083751841 0.57383491242302 0.56648261482925 CTSV other 1 1 1 3.15136081633367 0.57383491242302 0.0237029600634953 37.4353068563977 13.7103050458996 2.7304503241227 0.00667519081298522 17.9875254092663 26.8445807455303 0.670061699967554 0.503301699065768 LMX1B other 1 1 1 2.7304503241227 0.670061699967554 1.24309529657687e-07 303.84755652425 65.1181165096092 4.6660986651758 4.53485764986587e-06 -360.75522896429 127.952211350994 -2.81945286568498 0.00511328541610668 ARPC5L other 0.0013640484689338 1 0.0520465612475106 4.6660986651758 -2.81945286568498 0.519046062427701 -19.3392379705407 19.6111410102622 -0.986135276903103 0.324814094330494 57.0328683154104 108.389695362574 0.52618349119471 0.599126347668925 ENPP2 other 1 1 1 -0.986135276903103 0.52618349119471 0.0491178086244519 20.8366749474678 8.58886977812259 2.42600894945952 0.0158200593089506 -14.4253319730046 47.47020982983 -0.303881782379227 0.761416072658281 DSCC1 other 1 1 1 2.42600894945952 -0.303881782379227 8.91154689182695e-18 361.429652578144 38.3710780657766 9.41932493943933 9.49245093500509e-19 245.050273144559 216.972798069207 1.1294055076268 0.259575366676685 DERL1 other 1.26784577630022e-13 1 1.40089590898805e-14 9.41932493943933 1.1294055076268 0.000134141586390113 705.008361541309 164.588652265173 4.2834566772286 2.45121379948558e-05 381.682045616407 956.16262811002 0.399181095762811 0.690031990761281 MYC og 1 1 0.26769705904182 4.2834566772286 0.399181095762811 0.654160783391001 2.95053313774816 13.7753514839525 0.214189317868612 0.830536270962394 -67.2046801897238 76.1356083298101 -0.88269709356759 0.378064633494606 NOV other 1 1 1 0.214189317868612 -0.88269709356759 0.000409131140264709 114.04197618834 35.727650751574 3.19198082687582 0.00155653451071335 -220.520127359723 120.288663632874 -1.83325777092977 0.0677138179108997 IL33 other 1 1 1 3.19198082687582 -1.83325777092977 9.69668450710626e-42 260.885321042204 16.8407362004254 15.4913251972687 1.41849993816389e-40 -96.3238457972336 56.699772012121 -1.69884009016195 0.0903429867762673 RANBP6 other 1.48233216060133e-37 1 2.16860270546496e-36 15.4913251972687 -1.69884009016195 4.69142335472826e-49 210.433914120696 13.5001509356419 15.5875230672516 6.07933154332018e-41 -196.722612215001 40.0036926264006 -4.91761133283913 1.41716139163448e-06 POLR1E essential 7.18819886411464e-45 0.0211908142891104 9.29712172919956e-37 15.5875230672516 -4.91761133283913 6.50433726768513e-30 304.513787716501 26.9221603812563 11.3108971718521 4.98667428427488e-25 -194.321984255073 59.7548539270835 -3.25198659998728 0.0012735502101171 PLAA other 9.828704045199e-26 1 7.51392081154538e-21 11.3108971718521 -3.25198659998728 0.136130234541028 27.5052525007176 16.7391384849281 1.64317013838456 0.10135507763176 -43.2052695712463 53.09761165352 -0.813695159269599 0.41644015374967 IL11RA other 1 1 1 1.64317013838456 -0.813695159269599 3.10788820416895e-43 443.831366466699 28.3064307931841 15.6795241939711 2.34775153678003e-41 -140.648408525689 94.5939168397476 -1.48686525756157 0.138050640045887 UBAP2 other 4.75351500827641e-39 1 3.59135552581241e-37 15.6795241939711 -1.48686525756157 1.20483989775852e-37 250.945960596514 19.528320675938 12.8503604974963 1.42971671881224e-30 -173.276974555775 49.8340554345036 -3.47707954018534 0.00057958079530682 APTX other 1.83738084408174e-33 1 2.17331238426648e-26 12.8503604974963 -3.47707954018534 4.80589401809794e-22 136.440931024202 17.7517828985723 7.68604099113763 2.04877414130313e-13 -317.246429250285 55.8965678271431 -5.67559765442757 3.19128186043802e-08 RNF38 other 7.06514479600578e-18 0.000483798330042405 2.90147393891349e-09 7.68604099113763 -5.67559765442757 0.520024565086592 -49.1723981420292 54.2079608783531 -0.907106582599111 0.365055002979775 -146.578574497973 171.750365509862 -0.853439665545028 0.394074483625526 CCL21 other 1 1 1 -0.907106582599111 -0.853439665545028 1.16342779939244e-08 -4.15391241185425 3.16606807810637 -1.3120098208181 0.19049382171226 -62.1130373583804 9.97247040045363 -6.22845041039731 1.54291684346363e-09 SIT1 other 0.00013456205927773 2.35341106133507e-05 1 -1.3120098208181 -6.22845041039731 1.81262165961629e-10 168.875328035653 24.302431536985 6.94890664658999 2.19954574914778e-11 109.837499961633 76.1469490646576 1.4424412443415 0.150194054637298 DNAJB5 other 2.25109483907747e-06 1 3.02371554135345e-07 6.94890664658999 1.4424412443415 0.000349744301400023 9.28709078881691 2.32570064250556 3.99324428048985 8.15583627072425e-05 11.0735620525027 7.46480403715339 1.48343640333866 0.138981049108596 SPAG8 other 1 1 0.85301891555505 3.99324428048985 1.48343640333866 1.78499614573475e-38 316.705575343154 23.6280500315004 13.4037965435543 1.09468887900913e-32 -343.215095257023 75.1141875641281 -4.56924459129649 7.05195285604729e-06 DCTN3 essential 2.72372561877666e-34 0.104227863212379 1.66655434940349e-28 13.4037965435543 -4.56924459129649 4.02510577772582e-16 78.4155204317557 9.71907224538014 8.06821046823988 1.60874142556739e-14 -63.5128331223649 30.6131005069524 -2.07469456117131 0.0388450235675182 CD72 other 5.62025519743857e-12 1 2.30757870083387e-10 8.06821046823988 -2.07469456117131 1.41166844233956e-07 55.3643588855029 9.92477304284666 5.57840049807558 5.31791753527672e-08 -6.11307276799076 31.8555554932714 -0.191899738470484 0.847947195895711 TMEM8B other 0.00154507111014064 1 0.000669313100989928 5.57840049807558 -0.191899738470484 4.66439022779381e-58 545.170555844799 29.8096808261449 18.2883727948758 2.75086542582412e-51 -370.927394891499 88.8031903197644 -4.17696023707996 3.83859182693604e-05 GRHPR other 7.15657392650404e-54 0.556020026131686 4.21845213050128e-47 18.2883727948758 -4.17696023707996 0.00228214091114867 74.3713858109937 26.9909525960408 2.75541908150003 0.00621071595444282 -86.8207636715302 69.1063803545335 -1.25633498999828 0.209946600052454 ALDH1B1 other 1 1 1 2.75541908150003 -1.25633498999828 1.03906109858049e-12 109.649030426721 16.0905935903085 6.81448013780942 4.9839705149717e-11 -111.451203168086 51.6459968225863 -2.15798338738513 0.031701816298949 HINT2 other 1.36823565461079e-08 1 6.80461494409086e-07 6.81448013780942 -2.15798338738513 2.03820705833062e-18 239.791064925033 26.9540564196746 8.89628860277972 5.0257001081658e-17 -154.648228634397 84.8934273448174 -1.82167493375255 0.0694741680974892 ARHGEF39 other 2.91728576258862e-14 1 7.34204528801942e-13 8.89628860277972 -1.82167493375255 7.50881706786717e-30 304.015527030215 24.7131352616662 12.3017789451341 1.06763319061848e-28 -126.732817781109 79.0551661700579 -1.60309343362192 0.109909910328522 DENND4C other 1.13443208261337e-25 1 1.61853191697762e-24 12.3017789451341 -1.60309343362192 1.74662875910614e-34 10515.2207810072 834.198595150557 12.6051768033839 8.31051239766923e-30 -10708.7714400595 2668.52861282846 -4.01298730265773 7.48664456927461e-05 RPS6 essential 2.65487571384133e-30 1 1.26195130758607e-25 12.6051768033839 -4.01298730265773 7.95765961088251e-07 214.696596559251 41.4893583128483 5.17473890389779 4.04405635037152e-07 -35.1230179674483 144.180291456756 -0.243604847878829 0.807693457306786 CNPY3 other 0.00829745167626719 1 0.00490908000371599 5.17473890389779 -0.243604847878829 0.000258501231947748 298.373702905494 76.161319775168 3.91765405045905 0.000109417111381204 0.61586047254165 208.147167403049 0.00295877421838328 0.997641092582614 FOXP4 other 1 1 1 3.91765405045905 0.00295877421838328 4.83658303179145e-10 176.492323248999 34.1512359708891 5.16796298088429 4.17459153735352e-07 -177.98116306905 79.2692520805742 -2.24527365148013 0.0254330402328456 PPIL1 other 5.92287958073181e-06 1 0.00506544937142476 5.16796298088429 -2.24527365148013 6.46367306204189e-17 113.102568834411 12.5140621130756 9.03803799377288 1.59447034983005e-17 34.8433858268852 43.4418567284711 0.802069442949233 0.423111757283865 KLC4 other 9.10149803866119e-13 1 2.33542072139608e-13 9.03803799377288 0.802069442949233 2.53299509455289e-09 495.390882982511 93.9946596957516 5.2704151979062 2.50774515563571e-07 -312.013840967329 221.810834549713 -1.40666636776662 0.160496749375674 KIF13A other 3.01831695466922e-05 1 0.003072990913716 5.2704151979062 -1.40666636776662 4.18566022260808e-07 29.1992179495937 5.77111003456279 5.05954968363479 7.0976065054574e-07 -1.37487038267382 13.0590361618385 -0.105281152884123 0.916218679019577 ZSCAN9 other 0.00444851968458787 1 0.0085128692426456 5.05954968363479 -0.105281152884123 0.00245336675832504 334.302276220282 124.557402576073 2.68392138328437 0.00765503272876753 -336.942917267935 289.544886865531 -1.16369838512954 0.245413203866887 PIM1 og 1 1 1 2.68392138328437 -1.16369838512954 0.6454779492566 4.2150482551583 19.6676108226734 0.214314198768824 0.830438546714993 -34.9528216618749 46.5493790554306 -0.750876217280007 0.45327895371115 GMPR other 1 1 1 0.214314198768824 -0.750876217280007 1.08402010920385e-10 239.535466181104 40.1090631646558 5.97210324254554 6.22697023750465e-09 -127.907013291981 93.2371253422684 -1.37184638439293 0.171072262992218 CMTR1 essential 1.35318230231917e-06 1 8.10253367304105e-05 5.97210324254554 -1.37184638439293 5.96759002134767e-14 474.426895699427 79.7829495286342 5.94646974701222 7.21161249527463e-09 -454.603737762927 180.273107762417 -2.52175015677908 0.0121654300003455 TFAP2A other 8.05385949281082e-10 1 9.36067301886648e-05 5.94646974701222 -2.52175015677908 9.64198742899041e-14 341.902670030552 50.2997301321238 6.79730625059948 5.29732473169993e-11 -311.426487141283 138.923367828421 -2.24171420553174 0.0256713625556056 YIPF3 other 1.29665446945063e-09 1 7.22925906135089e-07 6.79730625059948 -2.24171420553174 2.42000429671189e-09 148.042350341066 33.671700168399 4.39664019341691 1.50093368197666e-05 -184.534928745037 76.0826977300834 -2.42545196543512 0.0158456584195845 TMEM14B other 2.88633912468827e-05 1 0.166393507983933 4.39664019341691 -2.42545196543512 3.31334745608499e-13 398.699494737053 59.7015619305558 6.67820877451776 1.08001180056873e-10 -351.206909274289 166.005668681213 -2.11563202669137 0.0351532252524279 TMEM63B other 4.4054267776106e-09 1 1.46654802399228e-06 6.67820877451776 -2.11563202669137 0.0375810568602264 9.18243077229183 3.85117471214559 2.38431945020122 0.0176967624091674 -2.34674677777957 10.5799023787022 -0.221811760995421 0.82460279884893 FRS3 other 1 1 1 2.38431945020122 -0.221811760995421 5.89329239143624e-05 93.5868282666402 23.3330752182243 4.01090843754467 7.54964842450809e-05 -46.8374467871989 64.4438724143255 -0.726794418654258 0.467888254545086 TJAP1 other 0.521261712022535 1 0.792637588089104 4.01090843754467 -0.726794418654258 0.0620749618118891 -22.2641523898344 10.8992307960549 -2.04272694160152 0.0419037494667747 -45.7099040171958 23.8570002747637 -1.91599545168084 0.0562620665791278 KIAA0319 other 1 1 1 -2.04272694160152 -1.91599545168084 0.363939870268656 -27.7949248698548 19.6144678043901 -1.41706240245956 0.157459262626643 -19.533204638729 43.9015738491943 -0.444931762716007 0.656676592769247 IRF4 other 1 1 1 -1.41706240245956 -0.444931762716007 3.79677205506889e-05 421.380170479832 128.996231052331 3.26660838880546 0.00120728576965206 -463.060117900535 286.185523487078 -1.61804172432727 0.10664501185902 SLC22A23 other 0.343152258337127 1 1 3.26660838880546 -1.61804172432727 0.00490602183306176 468.668420565116 198.84525204852 2.35695052175928 0.019031584866966 -503.630214346124 441.149575349531 -1.14163141593662 0.254466185637715 TUBB2A other 1 1 1 2.35695052175928 -1.14163141593662 1.01577298322013e-05 182.95578990117 38.0352774138745 4.81016052309458 2.33853819615719e-06 53.8631992557427 105.537356492386 0.510370934481654 0.610147933038435 LRRC1 other 0.0969047425992002 1 0.0273024334401352 4.81016052309458 0.510370934481654 0.731250753660195 4.38742619304911 12.689470306445 0.345753296796063 0.729758922636222 22.4523924936757 28.3755210722318 0.7912592137611 0.429388119737421 FOXF2 other 1 1 1 0.345753296796063 0.7912592137611 3.82011097615258e-09 68.9557398567208 14.1814354222954 4.862394941228 1.82628912720381e-06 -58.6355713047455 31.4623263565069 -1.86367564306378 0.0632887701830459 BPHL other 4.51957329588612e-05 1 0.0214406343533727 4.862394941228 -1.86367564306378 7.60477825308365e-09 145.011563755978 30.9233673550983 4.6893846355989 4.07317265508562e-06 -133.416955657019 68.6052608072854 -1.94470444521437 0.0526919206102177 RIPK1 other 8.87705765482455e-05 1 0.046906656295966 4.6893846355989 -1.94470444521437 0.0628331977149907 156.301844869225 101.203570500174 1.54443014309417 0.123478704418147 -226.566422973435 224.525914951764 -1.00908807351753 0.313699587372099 TUBB2B other 1 1 1 1.54443014309417 -1.00908807351753 5.78103487424527e-05 266.21389896478 88.2144955598807 3.01780220217971 0.00275187847909487 -403.20211141224 204.522879252486 -1.97142790520997 0.0495415878572531 UQCC2 other 0.511852827765677 1 1 3.01780220217971 -1.97142790520997 7.96598271098592e-06 2009.65999916924 454.028913090836 4.42628198607073 1.31801583081329e-05 -386.644577238746 1051.18998070435 -0.367816079239715 0.713254304954881 HMGA1 other 0.0767283454722163 1 0.146681981811211 4.42628198607073 -0.367816079239715 0.603829252263789 69.6570768369605 73.6348149551097 0.945980198081924 0.344872437015735 117.110579417306 172.425042928232 0.679197043703509 0.497503977640193 TCF19 other 1 1 1 0.945980198081924 0.679197043703509 8.02890769871882e-10 566.321821430792 96.5202026421789 5.86739155045362 1.10818622537702e-08 -172.754729470613 225.567167144489 -0.765868240744245 0.444321012816728 FLOT1 other 9.74950261855427e-06 1 0.000142978186798143 5.86739155045362 -0.765868240744245 0.000718979514490606 734.285745102751 333.37805754779 2.2025617117812 0.0283383551946077 -1633.67926461997 779.078010936728 -2.09693925600044 0.0367835244600278 IER3 other 1 1 1 2.2025617117812 -2.09693925600044 4.30266233304042e-08 245.933680334281 43.2570387749119 5.68540259110195 2.95554361449901e-08 41.2579719086794 100.802647853086 0.409294525366143 0.682599070009731 MDC1 other 0.000483748326103734 1 0.000375679148838969 5.68540259110195 0.409294525366143 0.00342074937367251 17.042005327505 5.99318528033999 2.84356390305661 0.00474816211841199 -8.12049909655951 13.561554507163 -0.598788220942549 0.549737750200684 PGBD1 other 1 1 1 2.84356390305661 -0.598788220942549 1.08659358887599e-06 41.3516306102678 8.11407312522579 5.09628517910567 5.94476184547457e-07 7.22932660309845 18.9076179487056 0.382349940786347 0.702456423062917 ATAT1 other 0.0112223385859113 1 0.00716165459524321 5.09628517910567 0.382349940786347 1.45922671177698e-09 149.948427210753 31.5701815278728 4.74968530283444 3.08015873663052e-06 -173.098099888797 74.5000655808526 -2.32346238274031 0.0207805934770575 TPMT other 1.7522394355018e-05 1 0.0357267611861774 4.74968530283444 -2.32346238274031 0.00177422938349986 118.348726094772 54.5767980842398 2.1684805677332 0.0308585605344748 -229.350731606546 128.791626772213 -1.78078915030855 0.0758954715898927 RNF144B other 1 1 1 2.1684805677332 -1.78078915030855 1.60410893639133e-06 155.141981134651 32.298253020531 4.80341710853623 2.40684439601049e-06 -16.3790101346849 75.2651942367061 -0.217617323661898 0.827866851876258 NRM other 0.0163394536260821 1 0.0280854672570464 4.80341710853623 -0.217617323661898 7.36636823754836e-15 723.804707169094 97.6953591396436 7.40879314578806 1.1429640135491e-12 -280.028862107393 226.763038893934 -1.23489640760359 0.21777502122811 MTCH1 other 1.01088671323876e-10 1 1.60346421460804e-08 7.40879314578806 -1.23489640760359 8.36283358842325e-12 292.5783425545 44.4675582554841 6.57959092049802 1.92640965262379e-10 -76.9859740261736 103.917147672292 -0.740839945578111 0.459333758519613 VARS2 essential 1.07780199287599e-07 1 2.60296472262527e-06 6.57959092049802 -0.740839945578111 2.98777197221835e-11 120.927938866306 17.2067769646296 7.02792505039653 1.28269846446385e-11 20.7673911987285 47.2702575564171 0.439333150955283 0.660718542993171 TAF8 essential 3.79925083987285e-07 1 1.77115003973168e-07 7.02792505039653 0.439333150955283 7.40287996458149e-09 109.275611411789 20.5753106069016 5.31100664770205 2.04864538486642e-07 -50.1082812373516 48.4209333260257 -1.0348474883779 0.301523992657336 FAM8A1 other 8.64508322263827e-05 1 0.00251942409430872 5.31100664770205 -1.0348474883779 4.75689731593018e-06 1011.65947645774 803.24683097038 1.25946276717405 0.208783959488571 -5011.47430685942 1507.1214089206 -3.32519615022166 0.000986546505365784 FGFBP1 other 0.0467270023343821 1 1 1.25946276717405 -3.32519615022166 0.290916968379899 134.596913932986 317.825802588371 0.423492720971143 0.672221195149014 889.133494809654 596.332351301825 1.49100328511212 0.136948786086499 FGFBP2 other 1 1 1 0.423492720971143 1.49100328511212 1.09909438347452e-10 136.511516758062 50.3450041331836 2.71152061874763 0.00706042375856942 -358.355456474715 93.940612411597 -3.81470215357544 0.000163708091128814 CPEB2 other 1.37177970001454e-06 1 1 2.71152061874763 -3.81470215357544 1.57555629070765e-05 80.9225410876904 48.2008403899639 1.67886162218324 0.0941582247806953 -275.82169617838 82.3877526509428 -3.34784828209807 0.000911866036180074 FHDC1 other 0.147787180068378 1 1 1.67886162218324 -3.34784828209807 0.000939554738263665 58.6013384807517 65.5387833304388 0.894147487988763 0.371917088957877 -328.555751397905 112.09347052788 -2.9310873314087 0.00362170377640183 TLR2 other 1 1 1 0.894147487988763 -2.9310873314087 0.928651595978559 -2.53461902510351 9.74555604732599 -0.260079467276674 0.794973475734786 3.69387578298226 29.7734040020801 0.124066290261073 0.901342423568351 MYO7A other 1 1 1 -0.260079467276674 0.124066290261073 1.66603257432265e-15 127.456271185752 20.4131541029651 6.24383035286243 1.40896421830777e-09 -225.056871136093 75.8783924707833 -2.96602054692645 0.00325202897762187 FCHSD2 other 2.30845473498146e-11 1 1.86715938210146e-05 6.24383035286243 -2.96602054692645 0.248752727619161 9.08574547909072 12.6771380467931 0.716703205846141 0.47408829209248 -44.5530418008966 43.0847964363583 -1.03407803879745 0.30189291042111 ARRB1 other 1 1 1 0.716703205846141 -1.03407803879745 0.216414612158222 30.0710964635682 37.1683704069649 0.809050709899654 0.419096637524851 221.511994580329 126.321230150234 1.7535610943377 0.0804783270536855 SLCO2B1 other 1 1 1 0.809050709899654 1.7535610943377 9.33913827053552e-28 317.895057930423 31.6508145199894 10.0438191797451 8.96544609422285e-21 -147.618956040982 98.5038242002292 -1.49861142183593 0.134975923922751 THAP12 other 1.40441961312313e-23 1 1.33540319573449e-16 10.0438191797451 -1.49861142183593 2.62242372339048e-17 25.1252464860659 6.38660989845284 3.93405059735252 0.000103059693569598 -92.2987667955575 17.8494889852882 -5.17094729555738 4.17818211582326e-07 ANKRD42 other 3.71072956859753e-13 0.006288164084314 1 3.93405059735252 -5.17094729555738 9.17550800619062e-12 275.793399221529 41.221757418086 6.69048135003881 1.1454814892766e-10 -76.1191861087922 171.333009866269 -0.444276244071154 0.657174223093662 IL18BP other 1.18097963547679e-07 1 1.55487657354406e-06 6.69048135003881 -0.444276244071154 3.87869581609219e-38 1722.74121963592 134.885150521084 12.7719116076209 5.85070810082875e-30 -1579.13458648874 558.299255170598 -2.82847338925109 0.00500191646137534 NUMA1 other 5.91772620661185e-34 1 8.88722560515887e-26 12.7719116076209 -2.82847338925109 2.27390990610088e-23 85.7910852293247 14.1020127624035 6.08360570046049 3.44789703323051e-09 -190.177680871554 39.6050187865151 -4.80185811542417 2.44704775102054e-06 CCDC90B other 3.3676605709354e-19 0.0364683526334592 4.52122737967516e-05 6.08360570046049 -4.80185811542417 0.225902800555848 -29.1221810191694 27.2814077773193 -1.06747354303983 0.28657288178061 -117.370637291145 68.1323123312435 -1.72268683206459 0.0859235302028502 SYTL2 other 1 1 1 -1.06747354303983 -1.72268683206459 1.17469890968949e-07 55.4154421465605 14.1120628468807 3.92681373005714 0.000106056973166072 -64.5489249388595 39.4789054613171 -1.63502316451268 0.103055898419622 RAB30 other 0.00129111157163972 1 1 3.92681373005714 -1.63502316451268 9.24102144415476e-08 70.0869131127485 33.578463830207 2.08725787657084 0.0376657416086681 -286.714611120634 84.470094013889 -3.39427361207259 0.000775822515724208 CREBZF other 0.00102279625343905 1 1 2.08725787657084 -3.39427361207259 0.511826763058453 29.2088136141717 26.4564135881431 1.10403526603705 0.270423167450598 68.992359337939 82.374338545912 0.837546747637744 0.402922341249533 LRRC32 other 1 1 1 1.10403526603705 0.837546747637744 6.01274237465786e-09 237.938867411575 62.7007294719008 3.79483411781049 0.00017756258772625 -422.064121968541 175.407110784228 -2.4061973319185 0.0167026607763263 PRCP other 7.05354807971114e-05 1 1 3.79483411781049 -2.4061973319185 4.88805962695587e-28 100.621884553071 11.5744594664768 8.69344135201323 1.94566685741646e-16 -128.515264333582 36.340199967341 -3.53644901373901 0.000466257192331567 NARS2 other 7.35555212664319e-24 1 2.83308551108411e-12 8.69344135201323 -3.53644901373901 1.35857055142468e-42 162.801228290472 11.1415348978823 14.6121005572954 1.46933291911955e-36 -88.8846076053541 49.4916779735469 -1.79595057683966 0.0735504324162301 RNF121 other 2.07739023018348e-38 1 2.242936701036e-32 14.6121005572954 -1.79595057683966 1.11995343501477e-12 238.418301285511 32.1430885951999 7.41740485141539 1.17568566137428e-12 -174.045879501385 149.859038085347 -1.1613972819061 0.24638256648116 MRPL15 essential 1.47385872047944e-08 1 1.64901670864357e-08 7.41740485141539 -1.1613972819061 0.260546856507221 12.5104235970788 15.6131908625628 0.801272699937089 0.423572081565875 -97.5248533352976 73.084922128799 -1.33440455971791 0.183026019598857 PI15 other 1 1 1 0.801272699937089 -1.33440455971791 0.000101003588691681 159.242455511102 47.6329873242753 3.34311292355049 0.000928652648459839 -520.489701188891 224.822627180091 -2.31511261885558 0.0212512055163361 GGH other 0.869741902224065 1 1 3.34311292355049 -2.31511261885558 0.572273754621111 7.02965946078291 7.53535263636667 0.932890575930951 0.351586460111927 -13.0485722052597 35.0531066707674 -0.372251519039867 0.709954325033818 SLCO5A1 other 1 1 1 0.932890575930951 -0.372251519039867 0.459261396613573 252.972599845992 214.660359285823 1.1784784144014 0.239489784185786 563.247009201693 997.237026319658 0.564807557617849 0.572604123789749 SULF1 other 1 1 1 1.1784784144014 0.564807557617849 4.03204456883118e-07 115.013095806161 21.6926137589449 5.30194733950563 2.19011890634512e-07 -87.1764821116589 101.124234615439 -0.862073096950291 0.389317982351251 TGS1 essential 0.00428848260340885 1 0.00268975249828947 5.30194733950563 -0.862073096950291 8.85287087367143e-11 430.026357306163 62.1904314112338 6.91467075477603 2.67038548266987e-11 -118.076789383979 288.217741524652 -0.409679115377703 0.682323384832412 SDCBP other 1.10926472047103e-06 1 3.66590519060919e-07 6.91467075477603 -0.409679115377703 7.74131360355934e-05 25.4058471040134 13.2845008476817 1.9124427327239 0.0567148058689864 -64.0596274478112 22.6768052771648 -2.82489648188311 0.00502743934183751 NEK1 other 0.67511995936641 1 1 1.9124427327239 -2.82489648188311 0.0144778525203726 134.673429665651 200.812910470041 0.670641291689971 0.502935841057672 -788.518484340751 340.283302711584 -2.31724118714423 0.0211253426637586 DDX60 other 1 1 1 0.670641291689971 -2.31724118714423 1.28739235824653e-07 963.558432642941 247.561221432508 3.89220261181186 0.000120902434774137 -412.623928112058 464.927943063959 -0.887500814411781 0.375475880883811 SORL1 other 0.00141136824234567 1 1 3.89220261181186 -0.887500814411781 0.00867885312729231 -206.500205501516 337.421008710283 -0.611995697276875 0.540976546658481 -1748.59828341436 637.996496565412 -2.74076471082171 0.00647504339768295 TMPRSS4 other 1 1 1 -0.611995697276875 -2.74076471082171 1.99150612847496e-13 62.2245069833294 16.0820823690353 3.86918220883743 0.000132338634627442 -87.8545171954235 29.9784287941469 -2.93059111932432 0.00362656246623484 BUD13 essential 2.66204624193248e-09 1 1 3.86918220883743 -2.93059111932432 0.536742028732437 0.709340040157794 2.84772831358064 0.249089787384209 0.803456815682365 -17.3046434064224 17.8395067720559 -0.97001804071897 0.332796158609214 TRPC6 other 1 1 1 0.249089787384209 -0.97001804071897 7.43385673758699e-15 269.640956472015 31.7381607369427 8.49579654936203 8.09525369307276e-16 590.733684252805 412.986085725553 1.43039609485869 0.153600875608332 MMP7 other 1.01999948296431e-10 1 1.17356892788476e-11 8.49579654936203 1.43039609485869 0.18432109623383 1.35357413869579 1.27940717551512 1.05796978835202 0.290892914995835 -17.9809737661965 14.3417751345718 -1.25374813072143 0.21087822624001 C11orf70 other 1 1 1 1.05796978835202 -1.25374813072143 4.39534085718918e-72 267.213522343904 11.5813112372529 23.0728211054699 2.4205946303461e-69 -315.617863050056 150.951062539334 -2.09086214923339 0.0373518305918085 DCUN1D5 other 6.7494854202997e-68 1 3.71706511435947e-65 23.0728211054699 -2.09086214923339 6.89743373658857e-71 1041.61514370313 46.0380367832063 22.6250990807472 9.31360310966693e-68 -1508.11064952049 594.985613467454 -2.53470103374691 0.0117428363879906 YAP1 other 1.05910095025318e-66 1 1.43010375748936e-63 22.6250990807472 -2.53470103374691 1.10630690530622e-17 1797.41761944173 1158.44535500562 1.55157738919244 0.121754885118209 -13560.708259497 2185.39478574099 -6.20515265615912 1.69570202859534e-09 TRIM29 other 1.57261526589278e-13 2.58628473401362e-05 1 1.55157738919244 -6.20515265615912 2.748728163999e-09 80.1339795078544 23.1505381796116 3.46143052425569 0.000610525927348918 -89.6417225699329 43.6732429425433 -2.05255475733428 0.0409313299509843 SLC37A4 other 3.27016189670961e-05 1 1 3.46143052425569 -2.05255475733428 0.00128353082366122 4.63178948593374 10.6549816220894 0.434706473480099 0.664069414313245 -51.5948224866416 20.0752410927355 -2.57007237164947 0.0106213485983544 POU2F3 other 1 1 1 0.434706473480099 -2.57007237164947 6.67148118517411e-16 542.869609798842 111.291309276563 4.87791556526475 1.70467777756001e-06 -528.410786305984 203.331482601965 -2.59876522584741 0.00979600253820777 RDX other 9.2880361059994e-12 1 0.0200640574418813 4.87791556526475 -2.59876522584741 1.4698765382655e-32 238.707629175759 34.5691649159048 6.90521827057306 2.74591941903605e-11 -288.880563206818 63.518437518089 -4.54797968108943 7.7204401890817e-06 PPP2R1B other 2.22906777027963e-28 0.113930535870279 3.76932358651078e-07 6.90521827057306 -4.54797968108943 9.18437908763282e-14 38.900846514867 15.1091324116564 2.57465785956419 0.0104887804159223 -118.890613556359 27.6078579985826 -4.30640484902752 2.21720872501319e-05 FDX1 other 1.23557451865924e-09 0.323335548368674 1 2.57465785956419 -4.30640484902752 1.25417560361259e-14 32.5989840711766 14.6359605143091 2.22732112725404 0.0266276563365039 -128.326759350582 26.8925600519103 -4.77183128355481 2.79078446434358e-06 C11orf1 other 1.71370554477625e-10 0.0415380359672898 1 2.22732112725404 -4.77183128355481 0.870268232627224 -21.5026616609244 101.219176274204 -0.212436639502711 0.831901659014996 43.811823477801 187.01360594362 0.234270780763455 0.81492458411431 FXYD6 other 1 1 1 -0.212436639502711 0.234270780763455 0.196800184035655 -6.06329447438734 5.21744378495925 -1.16211975141285 0.246063780205813 3.12070309731373 9.53346911035189 0.327341816624247 0.743626111649944 ARHGAP20 other 1 1 1 -1.16211975141285 0.327341816624247 0.986709955282708 16.3726753162644 110.368615877952 0.148345389547783 0.882163630186576 8.59781801420655 203.918205997122 0.0421630720619811 0.966394995832412 FXYD2 other 1 1 1 0.148345389547783 0.0421630720619811 0.298902600244167 330.539714428322 218.817647609696 1.51057155599216 0.131906506634063 -135.862752422673 2842.51663069427 -0.0477966429309823 0.961908794768026 MMP13 other 1 1 1 1.51057155599216 -0.0477966429309823 3.50192326031356e-09 45.2995670987262 80.853343741108 0.56026832042686 0.575688447720524 -681.417635834413 149.385481310988 -4.56147163602767 7.24579859872249e-06 TMPRSS13 other 4.14837829416744e-05 0.107034936900329 1 0.56026832042686 -4.56147163602767 3.66053313701523e-08 40.8627910430101 63.5102704628028 0.643404456401157 0.520429809812933 -551.621950513565 127.913072770231 -4.31247517213848 2.16241033704497e-05 CASP1 other 0.00041334740183176 0.31547404407149 1 0.643404456401157 -4.31247517213848 5.01767498310312e-08 2.06145538714991 2.41950824153921 0.852014203447591 0.394853500657033 -20.1465232914187 4.90525589656405 -4.10712992680578 5.11121151220141e-05 CASP5 other 0.000562130128357043 0.737241148519931 1 0.852014203447591 -4.10712992680578 4.4506115086195e-18 47.5001749835893 8.89038928826492 5.34286783665236 1.75073343408931e-07 -46.4983525531525 16.8338954099064 -2.76218613820003 0.00607660648089484 ALKBH8 other 6.34946790003391e-14 1 0.00215812910420189 5.34286783665236 -2.76218613820003 1.13512721480166e-05 35.5201166009425 13.996100597291 2.53785805225047 0.0116273521081543 -79.6128473504103 27.2182106911592 -2.92498460878876 0.00369078359398142 MAP2K5 other 0.107746275228973 1 1 2.53785805225047 -2.92498460878876 6.0954337496724e-05 310.925223519022 166.039106043398 1.87260237017751 0.0620378738189266 -1043.12288462991 338.615297154288 -3.08055452129977 0.00224598601759788 SQOR other 0.53847061744606 1 1 1.87260237017751 -3.08055452129977 0.0376230230534851 51.6757430147716 45.772958894842 1.12895788829144 0.259763870569949 -156.100670344664 91.7896484588792 -1.700634798864 0.0899861582711571 CTDSPL2 other 1 1 1 1.12895788829144 -1.700634798864 0.0129794290458028 23.6590511577188 59.2516310194667 0.399297888524718 0.68994091140032 -304.551283307959 117.210922205378 -2.59831829301983 0.00980291649809721 SLTM other 1 1 1 0.399297888524718 -2.59831829301983 0.186941156742085 1608.49070207528 930.738329327442 1.72818788202006 0.0849192164483697 2312.56030248473 1869.14809044062 1.23722690262578 0.216909981345013 THBS1 other 1 1 1 1.72818788202006 1.23722690262578 1.67321488181847e-07 330.093658166449 91.1119007735648 3.62294777481168 0.000338620953282069 -469.218106171636 181.885445553207 -2.57974520580524 0.0103330369563729 MAPKBP1 other 0.00182296761374122 1 1 3.62294777481168 -2.57974520580524 0.0183034241050279 -97.1179415464206 121.50055998558 -0.799320937763144 0.424700970164911 -682.329658765271 242.178283762343 -2.81746838801972 0.00514323125285789 NUSAP1 other 1 1 1 -0.799320937763144 -2.81746838801972 1.18876425100536e-06 22.0837636414975 11.4670416190044 1.9258466459996 0.055014854475736 -86.0836465524598 22.8974525931602 -3.75952941499589 0.000202546098201572 NDUFAF1 other 0.0122454605496063 1 1 1.9258466459996 -3.75952941499589 0.047965401287176 50.268303541834 53.395050382672 0.941441260595707 0.347188929491297 -185.315496350893 103.918742844415 -1.78327307739224 0.0754895759731369 KIF23 essential 1 1 1 0.941441260595707 -1.78327307739224 0.179511153318879 141.578654681765 83.2274556116804 1.70110516585221 0.0898946610587038 214.08809836619 161.979293873126 1.3217004053239 0.187212036848828 ITGA11 other 1 1 1 1.70110516585221 1.3217004053239 0.0234419575721192 5.53272530093289 35.9788527276892 0.153777146336713 0.877882689123398 -176.054257019869 71.8333978293784 -2.45086912689332 0.0147875854409432 KNL1 other 1 1 1 0.153777146336713 -2.45086912689332 7.06337743043446e-05 72.2674259858796 29.3072084022137 2.4658583988648 0.0141943042532545 -144.602204403234 59.2970072304595 -2.43860881277252 0.0152890699136924 HAUS2 other 0.619175665551884 1 1 2.4658583988648 -2.43860881277252 4.17035754224848e-07 138.11607343339 51.6077211078321 2.67626762950456 0.00783051618907966 -344.752308135511 103.050585039231 -3.34546677250075 0.000919781234010542 RTF1 essential 0.00443267303165591 1 1 2.67626762950456 -3.34546677250075 1.57342148593116e-07 174.806417674115 46.9645792817281 3.72209057011876 0.000233364682751093 -249.024788375397 92.5958599083939 -2.68937281452713 0.00753388863130657 PARP6 other 0.00171770423619105 1 1 3.72209057011876 -2.68937281452713 8.43795272186528e-05 4041.45183690811 1350.34316321624 2.99290724535695 0.00297839855343853 -4972.13503956464 2628.07063434331 -1.89193356319627 0.0594024728643597 RPLP1 essential 0.732498675785125 1 1 2.99290724535695 -1.89193356319627 0.00110859215273856 218.808803056692 59.1321740833984 3.70033414885253 0.000253405851498289 107.633112558835 115.084472219134 0.935253127406185 0.350363091404224 PAQR5 other 1 1 1 3.70033414885253 0.935253127406185 0.541381460227517 -4.77726057819211 7.50297024659466 -0.63671591665452 0.524765105696242 -15.748266598767 14.6024627758044 -1.07846647791913 0.281637893071182 LRRC49 other 1 1 1 -0.63671591665452 -1.07846647791913 2.19729560934446e-07 125.199741714943 35.8578147256548 3.49156084030317 0.000547680512705036 -199.938470236075 72.6011351430275 -2.75393035993428 0.00622505220407238 TUBGCP4 essential 0.00237967114492005 1 1 3.49156084030317 -2.75393035993428 3.09994507716692e-08 71.0916515806737 32.8619299975315 2.1633437715318 0.0312570311388939 -280.407474508873 65.6103213968566 -4.2738317468798 2.54024526809963e-05 RMDN3 other 0.000351440773398414 0.369834308582626 1 2.1633437715318 -4.2738317468798 0.0680565315472133 -22.3628421507686 10.1867406715212 -2.19528923645693 0.028865180996303 -32.6149073622231 20.3409405280614 -1.60341196205894 0.109836459257555 ITPKA other 1 1 1 -2.19528923645693 -1.60341196205894 0.00119876503658018 177.16531456753 52.436173596852 3.37868502628815 0.000818639315998465 -17.4144118217291 102.056600646791 -0.170634840974165 0.864619074971105 UACA other 1 1 1 3.37868502628815 -0.170634840974165 0.342583964983205 -14.2844826935132 10.6635905607966 -1.33955656043551 0.181340119802405 -21.6538098438905 20.8991989669411 -1.03610716746336 0.300934467690197 SMAD6 other 1 1 1 -1.33955656043551 -1.03610716746336 0.15173570099617 -31.8973971653926 17.4649400212573 -1.82636740387136 0.068726528242964 -47.1354376030224 34.9314793593828 -1.34936849132791 0.178172543752293 PLCB2 other 1 1 1 -1.82636740387136 -1.34936849132791 0.00203376790017276 -24.698640643246 15.8114225633359 -1.5620758059125 0.119258512600282 -113.64518367303 32.0133068650993 -3.5499357861379 0.000443119069334914 TMEM62 other 1 1 1 -1.5620758059125 -3.5499357861379 0.000260809344438607 304.363178143789 131.541482782318 2.31381896954488 0.0213128792671123 -608.511465381774 260.213908712706 -2.33850476476111 0.019978418006934 ADAM10 other 1 1 1 2.31381896954488 -2.33850476476111 0.119062333170039 45.7245730308444 210.233310017518 0.217494425726514 0.827962097621584 -775.379443169909 423.26989349015 -1.83187950547669 0.0679016446704886 DUOX1 other 1 1 1 0.217494425726514 -1.83187950547669 0.022856044773523 140.980803165059 80.6724441106265 1.74757074388041 0.0814975739052589 -207.92886883461 158.38235561203 -1.31282849046612 0.190181459488204 STRA6 other 1 1 1 1.74757074388041 -1.31282849046612 0.0117330248016742 3.65141691293296 1.7831883252657 2.04769000626385 0.0414141534887969 -5.13429794690294 3.8192072306236 -1.34433604590359 0.179800960608779 CYP19A1 other 1 1 1 2.04769000626385 -1.34433604590359 0.038629019580652 0.845584202170506 34.3784867421025 0.0245963182880572 0.980392383042136 -167.243699878557 70.3258925715904 -2.37812409857872 0.0179914803000455 SEMA6D other 1 1 1 0.0245963182880572 -2.37812409857872 0.0463212972448588 20.4594154933142 8.69478030328006 2.35306871245453 0.0192317696024932 0.550553283464784 18.1066154551628 0.0304061951736985 0.975762298882635 BCL2L10 other 1 1 1 2.35306871245453 0.0304061951736985 0.00103794325090684 162.244593018293 63.4061717740198 2.55881388954587 0.0109656908024858 -200.481151668611 125.091580543598 -1.60267502255068 0.10999920572576 RSL24D1 essential 1 1 1 2.55881388954587 -1.60267502255068 0.000590478604278212 42.7671930142068 13.4508730709331 3.17951056326785 0.00162001467734712 -20.9158296383435 27.0152665363099 -0.774222590409449 0.439372595515135 SPTBN5 other 1 1 1 3.17951056326785 -0.774222590409449 0.0158002512751274 -86.4764811201959 36.9062551658698 -2.3431388725716 0.0197362448694137 -185.165299398667 73.6849985125344 -2.51293076116665 0.0124660227813666 GCHFR other 1 1 1 -2.3431388725716 -2.51293076116665 3.92701682648199e-08 388.614668981806 77.4910796760575 5.01496005225846 8.81973351744529e-07 -255.179307643344 164.947846565678 -1.54703024596164 0.122847418094853 BCAR3 other 0.000442650550546724 1 0.0105413455000506 5.01496005225846 -1.54703024596164 0.545085884723242 -11.5442120968178 10.5808997847108 -1.09104257026411 0.276077540072001 -11.1351415778704 22.4116760749815 -0.496845552319074 0.619640195093653 TTLL7 other 1 1 1 -1.09104257026411 -0.496845552319074 0.0851434930753699 85.8310959251959 43.1576580524595 1.98878020259731 0.0475768275841835 -28.3387660121334 91.576058929524 -0.309456055910231 0.757176038782286 FNBP1L other 1 1 1 1.98878020259731 -0.309456055910231 0.000805073943859761 26.3461698713684 22.5834531150283 1.16661388040061 0.24423499908812 -148.802666300247 48.5745099149254 -3.06338996648373 0.00237434856924027 KYAT3 other 1 1 1 1.16661388040061 -3.06338996648373 5.12640423147746e-08 34.1761965550561 17.4646276786707 1.95688091288628 0.0512307335740319 -176.026496044728 37.5644825446796 -4.68598218637405 4.12720215382821e-06 GTF2B essential 0.000574157273925475 0.061288951984349 1 1.95688091288628 -4.68598218637405 0.0790978099672457 -1.57385830914429 14.7609026734292 -0.106623446002212 0.915154738363452 65.4943279888419 31.1221320104392 2.10442934844159 0.0361231156283669 BRDT other 1 1 1 -0.106623446002212 2.10442934844159 1.0144556397719e-06 86.7979395677342 38.6828879884551 2.24383297321645 0.0255287974592779 -324.011961658966 81.8774128156402 -3.95728138587537 9.34824037137385e-05 RABGGTB essential 0.010500630327279 1 1 2.24383297321645 -3.95728138587537 0.209285442171432 -13.1560416567155 146.35847990869 -0.0898891657314512 0.928431701997972 -526.521480495948 308.236396073898 -1.70817426884824 0.0885768133635402 IFI44L other 1 1 1 -0.0898891657314512 -1.70817426884824 0.796870485822174 7.87789486309281 16.3972402599197 0.480440289842492 0.631242624752124 -10.4050336482329 34.9030582803016 -0.298112376419039 0.765810862454388 GIPC2 other 1 1 1 0.480440289842492 -0.298112376419039 0.00138707862838033 129.1049661204 49.3922403604107 2.61387143361656 0.00937678599195677 -169.929383538168 105.136535954362 -1.6162733724833 0.107023697795216 ARHGAP29 other 1 1 1 2.61387143361656 -1.6162733724833 0.0015296749646645 175.698751500342 136.919664137902 1.28322511311 0.20034467445144 -813.996768969783 288.357899397735 -2.8228696722715 0.00505853789149728 IFI44 other 1 1 1 1.28322511311 -2.8228696722715 0.0928016571265464 59.8883321022878 28.9121389789871 2.0713905721681 0.0391259174699052 -2.37676148130979 61.1963393031099 -0.0388382950414325 0.9690436071918 SLC44A5 other 1 1 1 2.0713905721681 -0.0388382950414325 0.00257352480262488 2200.67966926088 1111.728508177 1.97951177205083 0.048615071088772 -5017.2756173405 2362.41222625147 -2.12379345212821 0.0344542160278656 CLCA2 other 1 1 1 1.97951177205083 -2.12379345212821 0.0305957092470172 25.7508308563152 30.5005837149522 0.84427337840395 0.39914935734191 -131.376164642843 63.4653471924202 -2.07004563048437 0.0392525386140509 DBT other 1 1 1 0.84427337840395 -2.07004563048437 4.72580084287871e-11 73.5837098845245 22.3991156425174 3.28511674562945 0.00113278600706315 -225.288573726279 46.6078834536747 -4.83370101863136 2.08670123655479e-06 RTCA other 5.97483000565155e-07 0.0311314957481609 1 3.28511674562945 -4.83370101863136 0.212750497777282 40.185738251041 23.2782501149156 1.72632126782124 0.085254801614827 -11.7525544318858 82.5576623409116 -0.142355707497568 0.886888633253391 IFT172 other 1 1 1 1.72632126782124 -0.142355707497568 2.28138801293815e-09 430.259142812227 69.8126674763786 6.1630526144529 2.14499385000382e-09 -294.951532734054 242.88736856399 -1.21435517407875 0.225507505753424 SELENOI other 2.72260845464039e-05 1 2.82967588692504e-05 6.1630526144529 -1.21435517407875 0.0214506855161837 45.8479527817871 16.845965977982 2.72159832459067 0.00685238564361624 57.5886784902747 58.6093111066838 0.982585828136568 0.326553627011033 CGREF1 other 1 1 1 2.72159832459067 0.982585828136568 2.78411935441964e-06 495.093444614349 95.9353157185992 5.1607006336079 4.32687250405982e-07 249.997464736398 333.771466261912 0.749007899136064 0.45440265533364 HADHB other 0.0278272729474243 1 0.00524590022392212 5.1607006336079 0.749007899136064 0.76834491064307 11.5997427579209 16.2445722442584 0.714068833792823 0.47570513133004 -1.778385948866 56.5169839297514 -0.0314663986860388 0.974917205329864 KHK other 1 1 1 0.714068833792823 -0.0314663986860388 1.29104195732126e-06 394.515694759474 77.1354490246644 5.11458349886997 5.42729265413946e-07 -162.902705796384 259.422248339016 -0.627944237008929 0.530488337021816 ADCY3 other 0.0132590009016894 1 0.00655128496281174 5.11458349886997 -0.627944237008929 1.07368671490349e-05 140.171224981662 29.5828104364986 4.73826600358164 3.2507795236584e-06 -53.3948443885574 107.260349551121 -0.49780598899791 0.618963780012913 PPM1B other 0.102172027790217 1 0.0376602807815825 4.73826600358164 -0.49780598899791 1.04422848374671e-07 193.024988342759 34.285102530549 5.6299959485543 3.94412230231991e-08 -91.1903846165947 135.762319402732 -0.67169141642375 0.502264782918031 PNPT1 essential 0.00115126190333075 1 0.000498813147574399 5.6299959485543 -0.67169141642375 0.234723774917776 16.1657664994927 9.50227724643698 1.70125182419344 0.0898701412065809 13.0007358509437 33.8584734778679 0.383972888188295 0.701254348066946 DYNC2LI1 other 1 1 1 1.70125182419344 0.383972888188295 0.0258216990949312 13.8774650127226 8.28011904862834 1.67599824727418 0.0947183015134502 -53.590244357783 28.8012794662419 -1.86068971069831 0.0637079540642224 THUMPD2 other 1 1 1 1.67599824727418 -1.86068971069831 0.384752533201459 83.452066523849 112.40943020208 0.742393822064801 0.458395055499223 -394.992665052881 385.008195215899 -1.0259331358684 0.305700418376117 CYP1B1 other 1 1 1 0.742393822064801 -1.0259331358684 2.27606114764489e-09 592.300254551118 91.5003468287555 6.4732022891631 3.61810888790355e-10 234.688505124417 389.32913903947 0.602802311954937 0.547068500474312 RAB1A other 2.71647897971417e-05 1 4.86346196711996e-06 6.4732022891631 0.602802311954937 1.11404959455775e-07 1099.3096395467 193.669847528455 5.6762043941052 3.09600759030995e-08 927.043711548312 824.054963827336 1.12497800782929 0.261444086982346 ACTR2 essential 0.00122590017385135 1 0.000393131043817558 5.6762043941052 1.12497800782929 8.71100753834698e-09 199.573209666585 33.6324345423796 5.93395073482136 7.68153948612569e-09 -138.820127763566 117.011622957441 -1.1863789618067 0.23635275176914 PREB essential 0.000101430971776512 1 9.96372486745363e-05 5.93395073482136 -1.1863789618067 0.00577688077541196 161.60588512712 56.4339747482097 2.86362755499951 0.00446469950464044 371.829962985723 196.341152969655 1.89379535243531 0.0591539236492078 SLC5A6 other 1 1 1 2.86362755499951 1.89379535243531 8.73211890883176e-06 188.353086031645 40.2332237425849 4.68153104600174 4.21691364273394e-06 -127.544325683748 145.87625646527 -0.874332319558214 0.382595065944338 PREPL other 0.0837759488113319 1 0.0485113745460112 4.68153104600174 -0.874332319558214 1.98311357077603e-05 47.9913287226237 10.7742523574037 4.45426068841293 1.16615068893756e-05 -39.2632557895842 39.0649183412708 -1.00507712435441 0.315621484683798 SLC3A1 other 0.184132095046555 1 0.1301774014061 4.45426068841293 -1.00507712435441 0.0636993253398176 311.696928815399 143.645919058848 2.169897556837 0.0307500488705549 -303.704174467295 499.762873220172 -0.607696551187181 0.543819762121734 EMILIN1 other 1 1 1 2.169897556837 -0.607696551187181 2.67918523391975e-13 302.96000404792 38.5914242906876 7.8504488915955 6.30212927462934e-14 -23.4540902185877 140.483309854251 -0.166952858976066 0.867512589038225 FBXO11 other 3.57188975386181e-09 1 8.98935719733128e-10 7.8504488915955 -0.166952858976066 1.85284652846647e-05 307.72941386386 67.4631031859866 4.5614476555502 7.24657561910716e-06 -156.229458470872 235.464873413689 -0.663493693160727 0.50749211774525 ATRAID other 0.172592654126652 1 0.0821471812181987 4.5614476555502 -0.663493693160727 0.000345011297338906 131.515110260333 41.1164617116663 3.19859989856611 0.00151962198529943 -266.475349265604 138.212870147423 -1.92800676942293 0.0547416966735481 CENPO other 1 1 1 3.19859989856611 -1.92800676942293 2.49077927116195e-14 1043.63018131939 128.014382955791 8.15244472708819 8.23433343968736e-15 -197.169910126166 456.140299602343 -0.432257159251345 0.665846567597804 LRPPRC essential 3.38571626329044e-10 1 1.18385011862385e-10 8.15244472708819 -0.432257159251345 0.00327121610744884 105.379612492919 32.5909586473022 3.23340020873064 0.00135086209199211 175.169864070785 113.751452125787 1.53993519025217 0.124564387192815 TRIM54 other 1 1 1 3.23340020873064 1.53993519025217 0.0347224938651642 20.0135063436373 25.2801989344348 0.791667280607369 0.429144815901952 222.964733620284 86.5412336015173 2.57639883719401 0.0104343341151343 DTNB other 1 1 1 0.791667280607369 2.57639883719401 1.9121506138936e-12 305.647409726579 111.278856429427 2.74668000313626 0.00636102908521794 -1066.954102777 204.443074489439 -5.21883221254392 3.2444690586747e-07 ACTR1A essential 2.50185786321838e-08 0.00488811708379931 1 2.74668000313626 -5.21883221254392 0.0040055158057606 3.52147109691397 16.4018946300775 0.214699044002901 0.83013872384255 -87.6545589029772 30.1337906698519 -2.90884608124239 0.00388148823924646 MFSD13A other 1 1 1 0.214699044002901 -2.90884608124239 5.44365048185154e-07 1165.28008008024 358.057267589282 3.2544516912778 0.00125800521184843 -1685.33773990678 687.914612975844 -2.44992286559547 0.0148257651826139 MYOF other 0.00574250689330519 1 1 3.2544516912778 -2.44992286559547 0.916388108438997 -42.3216056063326 130.741768764538 -0.323703786527109 0.746373758357523 -91.9411859930474 239.451084773563 -0.383966462628438 0.70125830680925 LOXL4 other 1 1 1 -0.323703786527109 -0.383966462628438 0.00336888637347068 -17.742805208179 9.8533805945304 -1.80068201344298 0.0727034187703086 -67.3153772341107 19.9251988395193 -3.37840428977795 0.000820037146481343 STAMBPL1 other 1 1 1 -1.80068201344298 -3.37840428977795 0.564926786845109 -20.1696464982506 21.1780496816135 -0.952384511391603 0.341625336791728 -35.7729336137879 42.5472851629372 -0.840780639159314 0.401102582420285 CH25H other 1 1 1 -0.952384511391603 -0.840780639159314 1.42536836798664e-10 184.604424381884 38.3443763948564 4.81438066643451 2.29603535469505e-06 -214.761102522192 79.0226310727836 -2.717716426379 0.00693717391137907 ATAD1 other 1.77401347079618e-06 1 0.0268245810489023 4.81438066643451 -2.717716426379 0.231918350273557 15.9398705702476 11.2181591719409 1.42089894838689 0.156319830879663 -5.73506435353847 22.3504307202927 -0.256597486881154 0.797654407058211 BTBD16 other 1 1 1 1.42089894838689 -0.256597486881154 0.00493539693489468 78.4242699554472 84.3351112048994 0.929912450875991 0.353119569822949 -385.392549265708 162.028146434221 -2.3785530955399 0.0179690738473264 KIF11 essential 1 1 1 0.929912450875991 -2.3785530955399 0.568862964574888 -2.70522210933372 3.99469142602867 -0.677204274579759 0.498765628905446 -8.20260559917589 7.95879899705093 -1.03063359210546 0.303491009530191 CUZD1 other 1 1 1 -0.677204274579759 -1.03063359210546 0.0645877300324273 253.024648900188 179.157456693734 1.41230319725251 0.158832452126622 -390.17096091743 356.943261588999 -1.09308958286679 0.275176665169018 TACC2 other 1 1 1 1.41230319725251 -1.09308958286679 0.000599433762543212 310.299593938006 133.955912535798 2.3164307425033 0.0211661069379437 -467.520996439277 252.795544979186 -1.84940362172035 0.0653215553316648 DUSP5 other 1 1 1 2.3164307425033 -1.84940362172035 0.0986277904686918 -32.7036944818368 32.2083011913211 -1.01538091958259 0.310693779128849 -127.953776015802 59.2802377599345 -2.15845585056479 0.0316380557231502 CALHM2 other 1 1 1 -1.01538091958259 -2.15845585056479 0.029462282524112 -45.8454158899642 42.8772874213389 -1.06922379299461 0.285774709533182 -210.521850630371 78.9053920422401 -2.66802870097488 0.00801828237681198 ARL3 other 1 1 1 -1.06922379299461 -2.66802870097488 8.20561994047815e-06 281.321620320717 89.3209423199036 3.14955947635619 0.00178995657896101 -331.771356376819 171.607133909976 -1.9333191389984 0.0540815330546578 CEP55 essential 0.0789298582074593 1 1 3.14955947635619 -1.9333191389984 0.000211494337652508 61.3918589214168 36.0922642401739 1.70097000600705 0.0899231154542347 -183.969359929133 69.9916289216008 -2.62844804105361 0.0089925620652361 KIF20B other 1 1 1 1.70097000600705 -2.62844804105361 0.0628295874161004 -60.3041426074202 29.0880276675331 -2.07316024643119 0.0389573276794936 -104.558291372441 53.2741743111819 -1.96264499120533 0.0505535355506407 ENTPD1 other 1 1 1 -2.07316024643119 -1.96264499120533 0.477171577138142 5.61434433712102 17.8391113279804 0.314721077406754 0.753179189364883 -30.9321732553187 34.273247538428 -0.902516553782561 0.367463489269864 EXOC6 other 1 1 1 0.314721077406754 -0.902516553782561 0.896799304995806 -2.57342075733433 23.3453694393523 -0.110232599403478 0.912294225290606 -19.5722741025545 43.2535246247832 -0.45250125330457 0.651215488292103 PLCE1 other 1 1 1 -0.110232599403478 -0.45250125330457 0.307235102693992 14.7769964536121 10.6223091118817 1.39112845408379 0.165155952417806 24.932613886318 20.4080249810536 1.22170635862436 0.222720739595729 RBP4 other 1 1 1 1.39112845408379 1.22170635862436 4.31251483595374e-16 109.833307894335 12.4320346167434 8.83470093836549 6.9346659480491e-17 -4.20549271830601 56.5414282792064 -0.0743789615207265 0.940755614213039 DBR1 essential 6.02070196247502e-12 1 1.01197580179881e-12 8.83470093836549 -0.0743789615207265 7.12369048651098e-19 462.267047778297 48.6554379183589 9.50083007276505 5.08967890539255e-19 -166.895360084988 200.209581696303 -0.833603260498045 0.405126375394143 DNAJC13 other 1.02424421815055e-14 1 7.52152748638911e-15 9.50083007276505 -0.833603260498045 7.74082682179049e-06 202.430564664719 43.5900484411884 4.64396282875982 5.0145016643837e-06 -391.288457432302 269.525560927174 -1.45176752841645 0.147555210812192 GPR87 other 0.0746680155229911 1 0.0574361020638509 4.64396282875982 -1.45176752841645 1.00672571591605e-06 279.13141131548 112.5467944142 2.48013648694611 0.013647271189826 -931.101749871462 265.387078986127 -3.50846677776703 0.000515237965629469 ANXA7 other 0.0104236380625947 1 1 2.48013648694611 -3.50846677776703 1.98113101390754e-06 117.188579856721 43.4210351562296 2.69888959199324 0.00732653558245659 -321.916850639344 101.582343190726 -3.16902367604307 0.00167726713930407 FAM149B1 other 0.0200232911575635 1 1 2.69888959199324 -3.16902367604307 1.74279174671751e-09 103.389782138291 22.8678073896163 4.52119350039819 8.67919418881633e-06 -147.977038943715 53.0400401919893 -2.78991189312984 0.00558935840124886 ASCC1 other 2.08681883751955e-05 1 0.097909989644037 4.52119350039819 -2.78991189312984 0.116168427031599 21.574712351759 19.1979111476107 1.12380519869445 0.261951378355418 -55.6830966630596 44.0994008680495 -1.26267240749301 0.207640860127723 ZNF365 other 1 1 1 1.12380519869445 -1.26267240749301 0.368222577255787 23.0375691820629 18.2942370527798 1.25928012825013 0.208846937087738 44.6072538620633 42.202666270908 1.05697714868818 0.29131929394996 ADAMTS14 other 1 1 1 1.25928012825013 1.05697714868818 2.78499338321451e-08 4297.54086780555 848.728244832948 5.06350636257124 6.98444160524979e-07 -2147.32619947867 1921.65552860582 -1.11743554841828 0.264651659193065 RPS24 essential 0.000316319548465504 1 0.00837923459381817 5.06350636257124 -1.11743554841828 0.058641369161492 21.2667188136142 8.89898893136343 2.38979045570696 0.0174363868796763 15.6177634088717 18.6398904373542 0.837867768663156 0.402730335024851 TET1 og 1 1 1 2.38979045570696 0.837867768663156 0.113777705788388 -2.90693030334735 12.5261498979148 -0.232068937944871 0.816632809654597 -52.5377203034957 26.2158580709444 -2.00404351295006 0.0459078735795082 DNA2 other 1 1 1 -0.232068937944871 -2.00404351295006 0.306545576168589 61.7719193184855 63.7579699306823 0.968850159213726 0.333351648709692 -96.4707958202609 133.438439122667 -0.722961063202917 0.470231875063356 MYPN other 1 1 1 0.968850159213726 -0.722961063202917 0.153775763723252 -15.8387549526167 9.78716304425734 -1.61831931081502 0.106591450761625 -35.7498644046211 24.1627403587785 -1.47954511259038 0.139990886108485 AOX1 other 1 1 1 -1.61831931081502 -1.47954511259038 2.1859388735736e-09 311.636752270577 81.4038417690302 3.82828064988375 0.000155225279002289 -419.256675281856 142.823396699648 -2.93549015756527 0.00357128291576131 ATIC other 2.60913663949744e-05 1 1 3.82828064988375 -2.93549015756527 1.65800466133998e-19 67.9222323372748 16.9162677974752 4.01520200261978 7.40509292696643e-05 -186.058127375841 29.6796658955161 -6.26887539876079 1.17563461806155e-09 SMARCAL1 other 2.3964799375008e-15 1.7935481733147e-05 0.778275266624172 4.01520200261978 -6.26887539876079 9.63232234179451e-05 -13.4521869808061 24.2003297290857 -0.555867921280358 0.578690802378251 -174.914833398733 42.5416808078908 -4.11161077975765 5.00311328076467e-05 BARD1 other 0.831462064543702 0.72179915301592 1 -0.555867921280358 -4.11161077975765 0.104245856950657 -13.0933942792156 6.29666549853024 -2.07941715853761 0.0383928075678292 1.03553906760456 16.6890358297914 0.0620490649169816 0.950563362193293 STAT4 other 1 1 1 -2.07941715853761 0.0620490649169816 0.00699189345644409 -6.16184782604041 4.93038620864029 -1.24976980814242 0.212311393889927 -34.4917585535169 10.8808600526822 -3.16994781538565 0.00167450841991303 CARF other 1 1 1 -1.24976980814242 -3.16994781538565 1.1166908686636e-10 120.540099623527 20.9829649081842 5.74466478645789 2.18801002392773e-08 -154.046806050247 53.5680992767058 -2.8757190964443 0.00430844287576987 ASNSD1 other 1.39340686591844e-06 1 0.000279496400456528 5.74466478645789 -2.8757190964443 5.35392788452088e-06 152.851268788022 30.7761687932866 4.96654635002406 1.11279177768513e-06 -5.29178914381108 93.9355420114647 -0.0563342589023995 0.955110795244226 METTL5 other 0.0523346450711916 1 0.01323888377912 4.96654635002406 -0.0563342589023995 9.89350056525189e-11 472.274907252844 67.1293059296836 7.03530150821969 1.21899250563792e-11 144.01690184592 204.893200960536 0.702887656451122 0.482638388954885 SSB other 1.23767692071301e-06 1 1.68416004578935e-07 7.03530150821969 0.702887656451122 4.70758967980849e-11 517.618500271336 84.3007700943675 6.14013964157037 2.49642688481549e-09 -557.609181447597 229.844328553487 -2.42602976091201 0.0158298594099751 NAB1 other 5.95274715011783e-07 1 3.28829349267897e-05 6.14013964157037 -2.42602976091201 1.2630560444208e-11 308.380448126994 43.9286687804607 7.02002716422312 1.34705668600664e-11 -157.634908104973 133.078508124071 -1.18452566328748 0.237089593686619 PPIG other 1.62012198817856e-07 1 1.85934234369497e-07 7.02002716422312 -1.18452566328748 1.46790179221809e-05 67.9650291518119 14.4277818950426 4.71070533545871 3.69440600374693e-06 -9.52610072437819 43.7078505548926 -0.217949421063714 0.827608308575929 FASTKD1 other 0.138100200611878 1 0.0426519173132583 4.71070533545871 -0.217949421063714 0.453592908082593 10.9461129273564 11.4304918576199 0.957623964366804 0.338982173316668 -16.177272241528 28.6373989533825 -0.56490019459736 0.572541185438455 HECW2 other 1 1 1 0.957623964366804 -0.56490019459736 0.00591988747731604 352.201391246397 140.867142522064 2.50023806077582 0.0129157577310274 -209.833338548096 264.989213069175 -0.791856151870299 0.429036689015199 IDH1 other 1 1 1 2.50023806077582 -0.791856151870299 1.70180157594434e-19 469.760451061844 47.4458511528039 9.90098058413866 2.86762647158465e-20 -5.40751215630555 177.658474742661 -0.0304376819858346 0.975737516351758 OLA1 other 2.45944363755477e-15 1 4.26473408854069e-16 9.90098058413866 -0.0304376819858346 3.51275927853157e-08 96.0915767452807 16.9324435029273 5.67499762976728 3.17730099513547e-08 -82.554355014084 63.40263718124 -1.30206500367008 0.193857680928119 CIR1 other 0.000396941798474068 1 0.000403199496282691 5.67499762976728 -1.30206500367008 4.59665036148425e-09 1419.63857194221 233.178138253035 6.08821471248596 3.29715818419959e-09 -779.077170509469 689.542605714259 -1.12984631269081 0.25939517640166 SSFA2 other 5.42266843144297e-05 1 4.32620125348828e-05 6.08821471248596 -1.12984631269081 0.0262267066632231 57.3783485574748 21.3494476853612 2.68757999752929 0.007585818823977 -3.5263633897079 80.2795751780038 -0.043926034509885 0.964991642986991 CHRNA1 other 1 1 1 2.68757999752929 -0.043926034509885 0.000348800076160528 156.313968450939 42.2656690890918 3.69836729950838 0.000255937134127674 -28.8145216282147 93.4053779958752 -0.308488892679039 0.757914260367045 FAM117B other 1 1 1 3.69836729950838 -0.308488892679039 2.48910164446307e-16 177.344774279305 24.9664223638899 7.10333149437571 8.15387179120002e-12 -152.790365230692 55.0983505676646 -2.77304789810458 0.00588426648535765 WDR12 essential 3.48424448191940e-12 1 1.12980047538867e-07 7.10333149437571 -2.77304789810458 7.936286132498e-13 411.292496524075 62.2063687489517 6.6117425722749 1.61856218761006e-10 -216.561664356392 135.092604258041 -1.60306084515727 0.109920257034524 ABI2 other 1.04782785807371e-08 1 2.19040020849269e-06 6.6117425722749 -1.60306084515727 5.92981968935124e-05 933.243925058552 255.839343409944 3.64777329639706 0.000309305224954942 -1815.50248243559 863.622514200004 -2.10219448032493 0.0363272785547609 ITGAV other 0.524314656932437 1 1 3.64777329639706 -2.10219448032493 0.384183180778381 -86.3618647435334 81.9936094272588 -1.05327555826348 0.293029729264713 -226.955963517949 209.324174589916 -1.08423197637146 0.279099070478254 SLC40A1 other 1 1 1 -1.05327555826348 -1.08423197637146 1.06069013468706e-10 115.794531161151 17.1154066256043 6.76551446857972 6.33359576620013e-11 -22.1210262508279 70.3091841962067 -0.314624988239039 0.753251443662971 SLC35A5 other 1.32480197822414e-06 1 8.63459110806063e-07 6.76551446857972 -0.314624988239039 3.49608070346174e-17 169.228918451277 18.4155091679298 9.189478113697 5.13355299931584e-18 46.7472895655683 72.4997325906412 0.64479257916053 0.519523583189936 DIRC2 other 4.93681556135832e-13 1 7.54324277719469e-14 9.189478113697 0.64479257916053 2.64301860340505e-12 70.0653684050308 9.87038686428451 7.09854328593327 8.26576098533328e-12 -32.5656352346026 40.3418723999387 -0.807241540793037 0.420130701962814 SENP7 other 3.4472891644212e-08 1 1.14513852690807e-07 7.09854328593327 -0.807241540793037 8.48345530444453e-09 111.643264153679 19.2875100812256 5.78837100711889 1.70413109574302e-08 -104.635180398813 75.8762167226409 -1.37902474475366 0.168856273317526 COX17 essential 9.88577046626921e-05 1 0.00021870818482766 5.78837100711889 -1.37902474475366 9.20595306955933e-06 599.785716906732 131.725250536031 4.55330860610262 7.51497531411209e-06 -502.908253099958 518.587097006725 -0.969766228282066 0.332895434534588 PARP9 other 0.088137794687961 1 0.0850845505063771 4.55330860610262 -0.969766228282066 0.053422743266265 -26.224956707752 12.0605760146706 -2.1744365008646 0.0304069765276028 -43.2001584552874 23.8118020560811 -1.81423305777291 0.070581162505955 MNS1 other 1 1 1 -2.1744365008646 -1.81423305777291 4.08041450410076e-08 213.434064355013 41.5084522567934 5.14194224912546 4.77738744485546e-07 -101.472707570938 89.1414657683453 -1.13833339732867 0.255843576748382 USP8 essential 0.000459332260726622 1 0.00577968333078614 5.14194224912546 -1.13833339732867 0.14522089211888 29.4857181484573 32.1793018218856 0.916294527198336 0.36020896901698 -85.3601337618777 65.4542074502542 -1.30411988911106 0.193138839453647 SECISBP2L other 1 1 1 0.916294527198336 -1.30411988911106 1.87305914012189e-08 677.71664642844 133.287444358818 5.08462480985068 6.32307494061953e-07 -418.215779001979 277.567047794881 -1.5067198441763 0.13288147585168 TMOD3 other 0.000214858613963382 1 0.00760729146105936 5.08462480985068 -1.5067198441763 2.66461344265883e-05 176.665560059063 58.8907815132351 2.9998847955407 0.002915595040548 -295.367989458578 126.47088240863 -2.33546239128971 0.0201447334399926 SPPL2A other 0.244584867901654 1 1 2.9998847955407 -2.33546239128971 0.260817658372736 10.4516674099477 52.4821316902895 0.199147158724909 0.842274108642864 -147.398231041819 102.141998330614 -1.44307173788318 0.149978421219023 GLCE other 1 1 1 0.199147158724909 -1.44307173788318 0.127680289894546 15.3249246717256 10.2217348214038 1.49924889849774 0.134798039136594 -14.9034447298531 20.5797673488546 -0.724179456318418 0.469486331036701 SHF other 1 1 1 1.49924889849774 -0.724179456318418 0.0123601844404853 22.0347473749265 9.12044013946354 2.41597412383462 0.0162527769683497 -13.9515443697482 17.8471489713272 -0.781723982478234 0.43495480208118 APH1B other 1 1 1 2.41597412383462 -0.781723982478234 4.8117726442779e-06 112.908205685435 32.0839549716463 3.51914861447772 0.000495676795667711 -133.415891752619 62.8320626545086 -2.12337278319551 0.0344897047188119 INTS14 other 0.0472371720488762 1 1 3.51914861447772 -2.12337278319551 0.0861755053114851 56.3970056422278 31.3744185060197 1.79754743921093 0.0731913960873836 -35.7006129440767 61.4425319777791 -0.581040718780728 0.561622014467215 CILP other 1 1 1 1.79754743921093 -0.581040718780728 0.00318946552937393 31.6115507987459 13.4342161520817 2.35306254126688 0.0192243864390426 -38.9900121350011 26.3090853894967 -1.48199800782763 0.139324881652652 PARP16 other 1 1 1 2.35306254126688 -1.48199800782763 0.00592519857587011 -10.6962008999718 11.3808861530606 -0.939839020979513 0.348009018629359 -70.9415018280679 22.0800810684295 -3.21291853993694 0.00144770126216997 PPCDC other 1 1 1 -0.939839020979513 -3.21291853993694 0.00457228636126976 97.1133878482455 40.6236124716714 2.39056504184523 0.017400310706844 -95.5656080631357 79.8160169020121 -1.19732369231678 0.232066597011257 SEMA7A other 1 1 1 2.39056504184523 -1.19732369231678 3.02877752549545e-05 43.3743938385475 37.0011527452695 1.17224439295591 0.241970913822467 -268.475411238945 72.6987201093899 -3.692986765585 0.000260532645936032 UBL7 other 0.276739402504519 1 1 1.17224439295591 -3.692986765585 0.299382633261333 -43.6373423084731 30.4899504604939 -1.43120410657978 0.153350650654862 -2.43535990070077 55.9469978155305 -0.0435297691706476 0.965306468888299 ARHGAP24 other 1 1 1 -1.43120410657978 -0.0435297691706476 0.443415854075026 37.5902768419229 34.701956907067 1.0832321918499 0.279520895439575 -11.2603430683632 64.060779906264 -0.175775928498525 0.860581160130301 FAM13A other 1 1 1 1.0832321918499 -0.175775928498525 0.0636938675067518 -5.90932368172723 142.652571032477 -0.0414245858939471 0.966983246792033 -571.095330458386 263.340623136823 -2.16865641030121 0.0308450767541161 HERC6 other 1 1 1 -0.0414245858939471 -2.16865641030121 0.212101290831723 5.62785890302872 58.1877712617081 0.0967189287542324 0.923010152932195 -168.653403731012 107.416247965924 -1.57009211292238 0.117381920078518 HERC5 other 1 1 1 0.0967189287542324 -1.57009211292238 0.020811754083296 18.509030069646 6.64866031847687 2.78387362010489 0.00569396508688485 14.5916613794814 11.5061806850728 1.26815854703302 0.205671914779396 PCDH10 other 1 1 1 2.78387362010489 1.26815854703302 0.0315842765336324 -0.583467526286289 10.1013203166223 -0.0577615111686101 0.953974874473441 -46.0909523583866 18.4555034937437 -2.49740964119516 0.0130155886719481 ZGRF1 other 1 1 1 -0.0577615111686101 -2.49740964119516 3.07026803130636e-06 92.6762856842644 24.9311827386784 3.71728395943631 0.00023790034722306 -92.7270625709528 45.5502365744892 -2.03570979086606 0.0426081287118346 AP1AR other 0.0306136425401557 1 1 3.71728395943631 -2.03570979086606 1.07905486555208e-05 70.9993262442507 27.2193589699853 2.60841286977189 0.00952713969672857 -135.56270322524 51.0834380038468 -2.65375057988524 0.00836157548566649 COPS4 essential 0.102628908262659 1 1 2.60841286977189 -2.65375057988524 6.60671528880742e-06 566.625748350822 188.80782987604 3.00107124118122 0.00290320171114365 -841.43829280276 356.751367917194 -2.35861265989053 0.0189480664727223 HNRNPD other 0.0640785315861432 1 1 3.00107124118122 -2.35861265989053 0.614059884666807 -1.03290697674365 4.9754439444841 -0.207600967525473 0.835673432654849 7.53075581395385 9.42716699223611 0.798835516561436 0.424982009202569 PRKG2 other 1 1 1 -0.207600967525473 0.798835516561436 0.0116512855894596 37.3342213221844 25.8925624894875 1.44188978349834 0.150317554543767 -89.4989672066892 49.0596443591563 -1.8242889522697 0.0690466887637717 RASGEF1B other 1 1 1 1.44188978349834 -1.8242889522697 6.69972495632807e-10 882.19955375887 163.710804036009 5.38876807156127 1.38668627306099e-07 -433.571722764158 307.241280654519 -1.41117665516989 0.159173201695909 SEC31A other 8.15289529935563e-06 1 0.00171685627467681 5.38876807156127 -1.41117665516989 0.138772694531492 23.7474665776012 13.4358237155265 1.76747381332181 0.0781139843636993 -3.73707183751534 25.5435463095344 -0.146301997077063 0.883776275702778 FGF5 other 1 1 1 1.76747381332181 -0.146301997077063 0.045053594068324 37.0858208590875 24.3668240013067 1.52198008477012 0.129010939994991 111.551671207195 45.729994765636 2.43935455883806 0.0152616007726123 GPAT3 other 1 1 1 1.52198008477012 2.43935455883806 0.432609223825281 31.1289523948106 28.3218420041552 1.09911468294483 0.272546860884338 52.554703057649 51.1017628060274 1.02843229219189 0.30452567996209 FGF2 other 1 1 1 1.09911468294483 1.02843229219189 3.49397025213527e-06 33.9334784282539 9.38213571391815 3.61681811721339 0.000346571311213632 -35.8825149353433 16.9284071917449 -2.11966279691342 0.0348064676097022 BBS7 other 0.0346671728416861 1 1 3.61681811721339 -2.11966279691342 0.000206221061682334 172.712321739386 58.9319475544356 2.93070785722551 0.00362523618193694 -186.24445427923 105.879798677841 -1.75901783536549 0.0795301809676977 KIAA1109 other 1 1 1 2.93070785722551 -1.75901783536549 0.0013525880794345 46.0912924070001 14.6847820191978 3.13871137799279 0.00185495846245301 -13.8321695144034 26.5181637226548 -0.521611136392011 0.602301931522606 BMPR1B ts 1 1 1 3.13871137799279 -0.521611136392011 1.80528866689787e-09 152.64342641837 42.8941235912962 3.55860928347173 0.000429469256103372 -285.190974214255 77.3838255470528 -3.68540805779687 0.000268212665588402 RAP1GDS1 og 2.16038894767668e-05 1 1 3.55860928347173 -3.68540805779687 9.03045222060168e-05 97.3616373114999 23.6393861534881 4.1186195224927 4.86444530600279e-05 3.48767495917406 42.5075327977259 0.082048397769175 0.934659845512853 LARP1B other 0.781766248737487 1 0.519571403134158 4.1186195224927 0.082048397769175 0.785672147467973 -8.81213630284886 20.1461110819388 -0.437411283349322 0.662108159404051 12.1080334741927 37.5928585845731 0.32208334056196 0.747599865447323 MMRN1 other 1 1 1 -0.437411283349322 0.32208334056196 0.453200786697396 20.7060700577564 23.1467639716382 0.894555717729165 0.371701191726065 47.9785351876591 41.945529027668 1.14382954035486 0.253554629000428 PDE5A other 1 1 1 0.894555717729165 1.14382954035486 0.0101065441123418 12.2612676766402 5.11852125229851 2.39547069793531 0.0171751649760266 -8.63485291522779 9.23546776774595 -0.93496649356346 0.350512773445317 PRDM5 other 1 1 1 2.39547069793531 -0.93496649356346 0.107489633800673 16.0997993626952 17.293693202833 0.930963627830392 0.35258081526981 -51.4595139680235 35.4600834341305 -1.45119551293818 0.147714283265116 NAAA other 1 1 1 0.930963627830392 -1.45119551293818 1.0218160701417e-08 151.295318327504 32.1182999135006 4.71056434291246 3.70129609816651e-06 -142.849833014991 65.8573956029577 -2.16907807706528 0.0308197495779948 NUP54 essential 0.00011855110045784 1 0.042724060861136 4.71056434291246 -2.16907807706528 0.236287489162156 -631.900222105148 371.16025984123 -1.70249967594983 0.0896420271030861 -465.017067515789 761.050495520961 -0.611019991777905 0.541624218353468 CXCL9 other 1 1 1 -1.70249967594983 -0.611019991777905 1.04777818768853e-06 206.952604067062 58.6718215741145 3.52729127057421 0.000481841940631269 -254.195682199699 111.410586530454 -2.28161156058732 0.0231749636907635 BMP2K other 0.0108329786825118 1 1 3.52729127057421 -2.28161156058732 3.8776590235158e-08 561.201949247681 105.521752449797 5.31835319466172 1.98160365454705e-07 -160.257335838608 220.816126486645 -0.725750145102289 0.468527410779539 G3BP2 other 0.000437206054901406 1 0.00243776881582378 5.31835319466172 -0.725750145102289 0.00567592557602894 346.60577744238 118.090012345678 2.93509815569991 0.00357878690085438 534.919489636429 223.59864551897 2.39231990155793 0.017326162408046 SEPT11 other 1 1 1 2.93509815569991 2.39231990155793 0.0820301826676177 95.0021377346503 70.6032291673058 1.34557779941662 0.179400357571186 291.424114453508 133.263815012609 2.18682103934916 0.0294861677676651 FRAS1 other 1 1 1 1.34557779941662 2.18682103934916 4.80460361075125e-07 681.438006670121 165.18329147156 4.12534464351346 4.73503215050922e-05 -667.307199038241 338.702278848467 -1.97018809943346 0.0496868904829109 SCARB2 other 0.00508615338234128 1 0.506601089782981 4.12534464351346 -1.97018809943346 3.82465027494397e-06 117.143248921141 49.3919273043186 2.37170840083615 0.018303112278965 -306.09164262078 94.5316398997191 -3.2379808807452 0.00133127225425386 CCNG2 other 0.0378487391208455 1 1 2.37170840083615 -3.2379808807452 8.55867710049988e-05 135.930483446835 46.0848992850339 2.94956668140053 0.00341896516549172 -158.049305508732 86.5467257389804 -1.8261731354852 0.0687646750446633 CNOT6L other 0.74255082523937 1 1 2.94956668140053 -1.8261731354852 3.11632182722868e-13 542.997258905998 79.3389979888577 6.8440145788362 3.98957530449725e-11 -225.991055332565 166.025770123239 -1.36118058759682 0.174423416516572 USO1 other 4.14844761640682e-09 1 5.45933484667404e-07 6.8440145788362 -1.36118058759682 0.139670582527748 30.3758253166673 59.0120616460851 0.514739266335773 0.607093932451608 -194.276562847992 120.914793940578 -1.60672285430571 0.109110765764063 SHROOM3 other 1 1 1 0.514739266335773 -1.60672285430571 0.000364977330741399 10.8485112493238 110.702158975195 0.0979972870425644 0.921996381358181 -762.263787380106 208.950669950354 -3.64805620178781 0.000308830316327573 ANXA3 other 1 1 1 0.0979972870425644 -3.64805620178781 3.98691194023243e-07 130.024366650198 43.0265898273508 3.021953800474 0.0027154675895744 -245.978507737008 78.1424057792991 -3.14782358290497 0.00180079484107689 PPA2 essential 0.0042436690691834 1 1 3.021953800474 -3.14782358290497 0.00836420092469206 93.2116109623922 37.6996522738718 2.47247932912616 0.0139373932275741 -55.0271327053338 68.4968094436252 -0.803353224074221 0.422366914566988 CENPE essential 1 1 1 2.47247932912616 -0.803353224074221 0.00296522405260118 31.9070125374414 15.0061926104313 2.12625636400681 0.034251891321609 -45.9500886154228 27.2533797559117 -1.68603266923088 0.0927703424734322 GSTCD other 1 1 1 2.12625636400681 -1.68603266923088 1.09642111643926e-10 54.4900571077169 12.3442811658002 4.4141944254058 1.39065869516284e-05 -75.1784141121357 22.4189700318416 -3.35333933741649 0.000894886002296975 INTS12 essential 1.36855283753948e-06 1 0.15448827444564 4.4141944254058 -3.35333933741649 0.00271604123397699 44.6480000964749 13.3640625536722 3.3409002627129 0.000934193421361668 49.9240879668125 24.4566315936932 2.0413313164388 0.0420404563872881 ENPEP other 1 1 1 3.3409002627129 2.0413313164388 0.000868448134329603 -0.473182276495254 12.8218833035977 -0.0369042725854855 0.970584488496407 -84.0448969303156 23.4802502717653 -3.57938675940685 0.000398124226366589 CASP6 other 1 1 1 -0.0369042725854855 -3.57938675940685 0.026960183226653 13.2205860863313 35.8989316055958 0.368272410766412 0.712915149993876 171.323114958793 65.1628005224095 2.62915518647598 0.00897560365158319 LEF1 other 1 1 1 0.368272410766412 2.62915518647598 0.0113966428263248 -4.27837496836861 66.779400158915 -0.0640672865911847 0.948956903460964 -342.964317070186 121.216218336794 -2.82935997984423 0.00496050764678733 HADH other 1 1 1 -0.0640672865911847 -2.82935997984423 0.303706941139718 4.42315520203204 10.6110734188668 0.416843332189892 0.677074244138803 29.9667264172084 19.4316742422044 1.54215874780993 0.124029520039068 EGF other 1 1 1 0.416843332189892 1.54215874780993 0.00169692447463372 175.027898265338 81.4627915048061 2.14856249131865 0.0324238998649243 -283.851197965115 147.869125776403 -1.91961098352833 0.0558016013726459 PAPSS1 other 1 1 1 2.14856249131865 -1.91961098352833 4.54736523386214e-13 251.010456344763 40.4215011476819 6.20982519742857 1.65680826383756e-09 -180.874663903203 74.0224303119112 -2.44351155644369 0.0150884697545779 SEC24B other 6.03253471924152e-09 1 2.19146029057794e-05 6.20982519742857 -2.44351155644369 2.46255438292893e-09 299.112068299733 64.7031597736734 4.622835567011 5.49891912697961e-06 -285.255435841337 116.842659428533 -2.44136377275643 0.0151733829906132 PPP3CA other 2.93610359076616e-05 1 0.0628141531874881 4.622835567011 -2.44136377275643 0.109850218435911 54.4406812951824 46.1460767998782 1.17974668857063 0.23897727900633 -97.4085527971318 83.8431878938794 -1.16179447900314 0.246184765618862 SLC39A8 other 1 1 1 1.17974668857063 -1.16179447900314 0.0381990533670959 -485.367651653313 264.874090931831 -1.83244669173108 0.0678140204995242 387.333144869143 392.316157104971 0.987298478164655 0.324242252206647 FBN2 other 1 1 1 -1.83244669173108 0.987298478164655 4.19988692696378e-05 91.9901145389667 48.0634156683686 1.91393210947983 0.0565206564606058 -465.057442154944 135.550540111302 -3.43087856214429 0.0006805570677852 MAPK8IP3 other 0.377905825688201 1 1 1.91393210947983 -3.43087856214429 6.29281032180909e-07 179.290840431864 35.3496412689219 5.07192814399193 6.68325545235326e-07 -110.374757450175 70.930996425934 -1.55608637988651 0.120675973638372 RGS3 other 0.00660745083789954 1 0.00802926310045721 5.07192814399193 -1.55608637988651 9.85281271537254e-10 269.831405294653 46.6193820728667 5.78796614834798 1.70784959126826e-08 -292.637239820476 139.592664788248 -2.09636545204138 0.0368396794089732 GUCD1 other 1.19110652916139e-05 1 0.000219168338047456 5.78796614834798 -2.09636545204138 4.83005660445684e-16 164.683297498505 22.878515778608 7.1981635125338 4.44925122260572e-12 -221.656329150059 64.2482200707084 -3.44999953159971 0.000636484345141324 RNF185 other 6.73841196887774e-12 1 6.18846352552229e-08 7.1981635125338 -3.44999953159971 0.000519639334859401 139.992233402594 38.805662811833 3.60752073947069 0.000358553818986778 -63.4134467972503 97.3170217909303 -0.65161721588114 0.515115842186527 KIAA1644 other 1 1 1 3.60752073947069 -0.65161721588114 0.497152736700254 8.26591646627598 23.9598742185285 0.344989977446702 0.730328548476425 -60.9751398843568 60.0866840682203 -1.01478623475258 0.310974386269739 PARVG other 1 1 1 0.344989977446702 -1.01478623475258 2.77526469992238e-11 738.907593090924 110.932948963851 6.66084873784167 1.25771247608897e-10 -972.139329838142 542.315185010774 -1.79257257902308 0.0740257372887757 B4GALNT3 other 3.5326344365312e-07 1 1.7062127450623e-06 6.66084873784167 -1.79257257902308 0.980760374848052 -0.5301915179116 3.85407044052821 -0.137566639243609 0.890669440182619 1.61049128293467 14.9391194761638 0.107803628286412 0.914219024187478 ERP27 other 1 1 1 -0.137566639243609 0.107803628286412 2.42316480188198e-05 254.373932773503 56.9685867667579 4.46516136717532 1.11055260381572e-05 -131.41528711361 259.38433483416 -0.506643113963036 0.61275415771264 ETV6 other 0.223197709901349 1 0.124159781106598 4.46516136717532 -0.506643113963036 4.90624633754005e-11 282.973180369088 40.1468041202602 7.04846093157101 1.11749294602963e-11 16.2173830317454 210.349847247943 0.0770971942405531 0.938594406575359 GABARAPL1 other 6.20100474601687e-07 1 1.54493399788596e-07 7.04846093157101 0.0770971942405531 0.0551170244983709 108.620655535454 62.028767194231 1.75113355381269 0.0809183627913017 -219.950513395722 166.69612114089 -1.31946989462234 0.187992049587932 KIF21A other 1 1 1 1.75113355381269 -1.31946989462234 0.00210302789975222 86.4886748943261 32.4662203344791 2.66395884717369 0.00812917051961443 -158.206674824536 87.2497269035921 -1.8132626936397 0.070764571463162 CPNE8 other 1 1 1 2.66395884717369 -1.8132626936397 2.11124357212281e-22 104.545218870939 10.0008111192523 10.4536739694726 4.22903257882628e-22 -87.9487546161805 59.0368842208075 -1.48972554661316 0.137316385913691 YARS2 essential 3.11049515480854e-18 1 6.32790144769776e-18 10.4536739694726 -1.48972554661316 7.67088140186598e-09 69.6988073451982 11.0960092956415 6.28143015098013 1.12928947687532e-09 22.5421104751176 65.5271957707443 0.344011523917248 0.731070095329675 FGD4 other 8.95268568411778e-05 1 1.50071278581961e-05 6.28143015098013 0.344011523917248 7.62775821474366e-08 21.5524581713066 3.85009589704905 5.59790164910587 4.92405612668943e-08 -27.3997702186477 24.2584459360658 -1.1294940447076 0.259597840767319 ALG10 other 0.000846681161836546 1 0.000620677274769203 5.59790164910587 -1.1294940447076 0.331388033720938 0.978490662283565 5.99703897592487 0.163162298296162 0.870495276701048 -32.9582766552365 23.2473014031933 -1.41772483969728 0.157259535387347 PIK3C2G other 1 1 1 0.163162298296162 -1.41772483969728 1.77621741683242e-19 339.751676626826 35.8310674043814 9.48204173748062 6.69507733176164e-19 -217.405650315404 146.207617405027 -1.4869652770084 0.138037087949265 AEBP2 other 2.56627892383949e-15 1 9.88595118807924e-15 9.48204173748062 -1.4869652770084 3.29786123636894e-10 21.1663801324928 3.15604136645008 6.70662316327647 9.31428345632213e-11 -8.69013345281145 18.6544777728458 -0.465847050699064 0.641648981468406 ETFBKMT other 4.06164589871199e-06 1 1.2659974073833e-06 6.70662316327647 -0.465847050699064 6.20308475008242e-13 208.793066694808 28.554321753086 7.31213539233314 2.24179469806441e-12 -183.813705677501 119.493222547679 -1.53827724919007 0.124997612984544 ETNK1 other 8.20544050740902e-09 1 3.13313227001482e-08 7.31213539233314 -1.53827724919007 0.0324285949551585 67.3804198210598 26.5939008432065 2.53367944094867 0.0117701713632227 -14.1020146405556 71.1161451300651 -0.19829554336451 0.842941347039262 ZCRB1 essential 1 1 1 2.53367944094867 -0.19829554336451 0.00197866204096371 43.6339382632292 17.4051733173313 2.50695224159477 0.0126809730606316 -96.1960470740141 48.0677600593292 -2.00125920066342 0.0462219919818623 TMEM117 other 1 1 1 2.50695224159477 -2.00125920066342 0.00580335123041758 73.9034141497161 27.1642232766541 2.72061576718195 0.00687572608140925 -85.5809813773652 72.6670182683556 -1.17771422877596 0.239793959934262 PRICKLE1 other 1 1 1 2.72061576718195 -1.17771422877596 6.53754277202605e-08 535.17643331919 91.1691453928713 5.87014862334156 1.09168313937705e-08 78.477825107245 511.980272849945 0.153282908090183 0.878272094296339 C1RL other 0.000728020763092821 1 0.000140925376462184 5.87014862334156 0.153282908090183 5.7782276441682e-13 333.180304446086 43.2104016231846 7.71065048993475 1.6425989934554e-13 -58.199682189578 211.750397543654 -0.274850403421696 0.783610782428863 NDUFA9 other 7.64863993258545e-09 1 2.32986241231714e-09 7.71065048993475 -0.274850403421696 4.58938854947036e-16 239.699159949087 27.0210188222566 8.87084093778332 5.28582346761093e-17 87.6460370527506 151.742440160947 0.5775973877828 0.56394342103434 CLSTN3 other 6.40357384307599e-12 1 7.72100233913928e-13 8.87084093778332 0.5775973877828 7.54449505948309e-05 26.7955732518271 6.12750400529719 4.37299971222581 1.66121337138022e-05 -0.629523862755528 33.6775226229795 -0.0186927010577072 0.98509793696453 VAMP1 other 0.659087088396443 1 0.18363052607237 4.37299971222581 -0.0186927010577072 3.91899851429398e-14 196.419205521079 24.3204955856311 8.07628301937757 1.38473840419707e-14 -68.0684413274949 133.668462652835 -0.509233367217538 0.610940718753918 TAPBPL other 5.30279688969118e-10 1 1.98751503154405e-10 8.07628301937757 -0.509233367217538 0.240255895683125 -22.7814465889871 14.1447631261481 -1.61059230089708 0.108257625790636 -58.8915393013299 78.5790623176676 -0.749455867305365 0.454134805706689 CD27 other 1 1 1 -1.61059230089708 -0.749455867305365 0.513605671630887 1.73598925187384 2.68181586673572 0.647318584920923 0.517891321679339 -12.9866962711545 15.0603234599589 -0.862311908883125 0.38916367680929 RBP5 other 1 1 1 0.647318584920923 -0.862311908883125 4.13543260016425e-62 497.305420389092 23.4017481601397 21.2507807957764 4.68347125621853e-63 123.462475445845 127.572597810746 0.967782090860933 0.333886361406993 PEX5 other 6.34788904125213e-58 1 7.18959672542106e-59 21.2507807957764 0.967782090860933 0.0660740977116957 13.2335364177537 5.97144415682734 2.21613667819759 0.0273874999818881 -14.06551690536 33.0011307792147 -0.426213180374381 0.670239964613483 PIANP other 1 1 1 2.21613667819759 -0.426213180374381 0.00979303772308982 59.9469523725554 19.9287400908045 3.00806534178326 0.00284039411084187 59.8319521351795 53.1849524612653 1.12497895299907 0.261451709412226 SLC38A4 other 1 1 1 3.00806534178326 1.12497895299907 0.0122731147642683 233.511961580886 89.7985757407788 2.60039716281207 0.00974912597001134 -232.207586036385 239.650522817866 -0.968942538935594 0.333314879709156 AMIGO2 other 1 1 1 2.60039716281207 -0.968942538935594 3.15812745987906e-06 424.225090036012 99.8442334860509 4.24886921581986 2.83044778960329e-05 -548.853268366169 273.285373819365 -2.00835215107029 0.0454564627082843 SCAF11 other 0.031442316990556 1 0.307754588163566 4.24886921581986 -2.00835215107029 0.0496646074377533 49.9726030564485 20.6753214543588 2.41701698165923 0.016210677155106 49.2605466787898 53.6549303109272 0.918099164295392 0.359262760949446 COL2A1 other 1 1 1 2.41701698165923 0.918099164295392 2.3565835138797e-15 132.596736393829 15.3060942344219 8.66300274668581 2.44142596678822e-16 53.777406524534 70.2373438373052 0.765652622757229 0.444456332709675 LLPH other 3.25844802464146e-11 1 3.55227478167685e-12 8.66300274668581 0.765652622757229 5.850073534826e-06 295.528428652175 67.7001374248158 4.36525596392434 1.71771411697761e-05 -369.248618319259 224.574392158448 -1.64421515191606 0.101116862982805 LRIG3 other 0.0570148166704142 1 0.189618461373158 4.36525596392434 -1.64421515191606 7.92722215829791e-08 102.438228796255 18.8653440248314 5.42996876502337 1.1165600524364e-07 -71.9739083569781 61.8113113931252 -1.16441322364475 0.245123954618483 MARCH9 other 0.000879525298463153 1 0.00138754917716272 5.42996876502337 -1.16441322364475 0.0246741280853852 9.33400182364755 3.50094245099219 2.66613974788481 0.00806247239877452 -1.17048578416621 11.5500657244338 -0.101340183864936 0.919343885200708 INHBE other 1 1 1 2.66613974788481 -0.101340183864936 0.790056871118936 59.4201702028532 90.7273209834418 0.654931387356822 0.512989884706947 70.3724308087636 211.959281516215 0.332009196791791 0.74010311897797 GLIPR1 other 1 1 1 0.654931387356822 0.332009196791791 0.165467533574134 647.697619230199 379.473704293072 1.70683136117905 0.0888357626032735 -432.354893394833 886.842279492749 -0.48752174247052 0.626226682124344 PHLDA1 other 1 1 1 1.70683136117905 -0.48752174247052 6.86024473996756e-18 226.761538198216 25.1429728836636 9.01888329782797 1.92668348777133e-17 -263.324023425508 133.908254617686 -1.96645101661067 0.0501270539450442 TMEM19 other 9.77310465655778e-14 1 2.82066462609723e-13 9.01888329782797 -1.96645101661067 0.741100251415418 30.3271487871272 39.1900297170344 0.773848578480284 0.439598884206192 23.7250721223028 210.172116545874 0.112884013884517 0.910194187997262 LGR5 other 1 1 1 0.773848578480284 0.112884013884517 0.513599805057299 238.237195579336 236.177561382921 1.00872070227313 0.313870724430553 -219.847378283214 571.455402178527 -0.384714848166807 0.700704246763797 DUSP6 other 1 1 1 1.00872070227313 -0.384714848166807 0.732053514808235 0.698624793719164 18.5936521916668 0.0375732957956624 0.970051328278485 -34.7100794530944 44.9892145932073 -0.771520013561986 0.440968103442145 POC1B other 1 1 1 0.0375732957956624 -0.771520013561986 0.00650121315863298 81.2795719357908 90.7024279126849 0.896112417343833 0.370866332263529 -630.814431576501 219.46366165317 -2.87434569725447 0.00431966771500415 TMTC3 other 1 1 1 0.896112417343833 -2.87434569725447 0.896358614682469 270.819362904433 1231.27910323785 0.219949613529758 0.826050642000219 1323.5089775231 2979.20382874139 0.4442492201288 0.657162688643482 LUM other 1 1 1 0.219949613529758 0.4442492201288 0.212290239240225 106.279965592589 62.878261700295 1.6902497416224 0.0919540068114487 -32.6108792791893 153.02896443663 -0.21310265935109 0.83138258719156 SNRPF essential 1 1 1 1.6902497416224 -0.21310265935109 0.9114045794808 5.11940755974336 13.0744631283186 0.391557764896289 0.695645608663397 7.75006644771396 31.8197656708139 0.243561392874196 0.807726597462822 AMDHD1 other 1 1 1 0.391557764896289 0.243561392874196 0.229793239362314 42.3059095717865 54.6059015610627 0.774749768108456 0.43905961739846 -183.461743273951 132.896240164012 -1.38048859055406 0.168399773987649 NEDD1 essential 1 1 1 0.774749768108456 -1.38048859055406 0.739402379037549 7.08321493280502 9.37488855822339 0.755551907504204 0.450475414220115 6.76597950910486 24.0004387504178 0.281910659195224 0.77819481512183 SYCP3 other 1 1 1 0.755551907504204 0.281910659195224 0.896909488421408 -4.7508273802316 13.3267911385988 -0.356486969055262 0.721710842966746 8.38692133833803 33.6361051315714 0.249342820922091 0.803255582370169 GAS2L3 other 1 1 1 -0.356486969055262 0.249342820922091 0.567548602618042 -2.64842691369583 8.41557505102668 -0.314705400122685 0.753190439918327 20.4065975009218 21.5888267969528 0.94523883547957 0.345250120631839 TMEM132B other 1 1 1 -0.314705400122685 0.94523883547957 1.57697416612508e-05 75.0454543156297 17.9584000647984 4.17884967730127 3.7874133039859e-05 -64.875583036636 43.924916169567 -1.47696543770719 0.140671416613534 SLC15A4 other 0.147904407040871 1 0.408358902435759 4.17884967730127 -1.47696543770719 6.97661478000929e-05 126.283529317495 34.6874699855745 3.64060940074362 0.000317080924403352 -173.706289188485 88.0247560508906 -1.97337995561224 0.0493124073259614 TDG other 0.612267713093615 1 1 3.64060940074362 -1.97337995561224 0.0103180675505921 50.725102574265 16.8310926040478 3.01377360148716 0.00278631549033545 -0.964768260519103 44.8501413847969 -0.0215109301939934 0.982851491067819 RITA1 other 1 1 1 3.01377360148716 -0.0215109301939934 0.112184485747767 -10.875978607429 15.0173056731537 -0.724229688343624 0.469453881880092 74.0513055854635 40.0169079039868 1.85050043754345 0.0651629848239832 SDSL other 1 1 1 -0.724229688343624 1.85050043754345 0.931923401931538 15.2876658225495 41.0835217810137 0.372111862854332 0.710055865202544 12.0658488798024 115.21643139031 0.104723334460237 0.916660953648859 MMAB other 1 1 1 0.372111862854332 0.104723334460237 0.00765066212824828 915.17923355714 484.937436659643 1.88721093562316 0.0600368520913885 -3009.61371283755 1359.97982834347 -2.21298408264144 0.0276041121231282 GLTP other 1 1 1 1.88721093562316 -2.21298408264144 0.00319723360623298 59.5381769393397 27.9061906366577 2.13351143889664 0.0336430650014903 -182.500521765057 78.2613456556022 -2.33193692539061 0.0203241550949466 GIT2 other 1 1 1 2.13351143889664 -2.33193692539061 2.53649622477858e-05 112.037154705759 31.0431777427488 3.60907493537543 0.000356496830659601 -210.201113808672 87.0588499593415 -2.41447152020548 0.0163187314332827 TCHP other 0.233332287717382 1 1 3.60907493537543 -2.41447152020548 0.702378067895477 -8.39684733870779 14.469489101859 -0.58031401659019 0.56211128384804 20.9839850072408 40.5788702157373 0.517116048221145 0.605432386389604 FAM222A other 1 1 1 -0.58031401659019 0.517116048221145 7.83724653436286e-11 140.078908112495 39.182731444008 3.5750164153989 0.000404214850947618 -306.255170785037 73.3537976671856 -4.17504179094519 3.84499815878351e-05 NUP58 other 9.83809557458569e-07 0.556832633355027 1 3.5750164153989 -4.17504179094519 1.22894267331768e-06 82.1872194063277 22.2438521191866 3.69482852906743 0.000258728652782448 -85.3111175601526 41.6426054937304 -2.04864985148436 0.0413118015356749 MTMR6 other 0.0126519648218055 1 1 3.69482852906743 -2.04864985148436 0.0308227940421055 33.4665315276172 12.6908334609945 2.6370633284628 0.00877347189996087 28.853307625384 20.8643488942313 1.38289997793133 0.167665790922173 SLC46A3 other 1 1 1 2.6370633284628 1.38289997793133 7.2541822424006e-12 1229.45123373336 292.516983431221 4.2030080418303 3.42388911278992e-05 -1915.31781390718 490.793052404685 -3.90249577601579 0.000116167751030858 SLC7A1 other 9.36442385671494e-08 1 0.370259368657102 4.2030080418303 -3.90249577601579 2.33186750308311e-11 91.9545104389673 26.2781505450428 3.49927633915294 0.000533077725968621 -218.140553441718 49.0973529581249 -4.44302065791144 1.22622305184773e-05 LNX2 other 2.97243150618004e-07 0.180070855163839 1 3.49927633915294 -4.44302065791144 0.202724847955841 1.36197012106708 20.0698797427901 0.0678613991972896 0.94593834847266 -99.9649035751621 57.3414201450189 -1.7433280048235 0.0822367708431118 SUOX other 1 1 1 0.0678613991972896 -1.7433280048235 0.500813186293046 -5.96764907931483 6.85306937722684 -0.870799455080039 0.384518495560614 -16.529431310763 17.1729803403606 -0.962525489644621 0.336514745915456 CCDC65 other 1 1 1 -0.870799455080039 -0.962525489644621 0.159360916221881 41.311270497333 21.8857966045758 1.88758358874156 0.0599894283606378 2.71368835058878 59.4115281893676 0.045676124369991 0.963596973763397 TARBP2 other 1 1 1 1.88758358874156 0.045676124369991 0.0115536648342211 55.7329355174068 18.6979129490806 2.98070355066805 0.00309628952492532 10.70363600841 60.1302572181687 0.178007487471314 0.858829727381375 RDH16 other 1 1 1 2.98070355066805 0.178007487471314 0.502655170074912 10.3747616702058 20.1018381708648 0.516110098092561 0.606135065257679 62.3946152196407 54.8164529571654 1.13824612600157 0.255871849251517 ACVRL1 other 1 1 1 0.516110098092561 1.13824612600157 0.583746504139868 -3.60786243331433 3.71265160795043 -0.97177511231819 0.331896403013379 -5.66465560403617 10.3396116481251 -0.547859609897764 0.584170244827653 GPR84 other 1 1 1 -0.97177511231819 -0.547859609897764 0.558486721020512 -1.0768284565497 1.84605960891938 -0.583311855883158 0.560095540179003 3.83420209943062 5.01134249194457 0.76510478092325 0.444774810649223 NPFF other 1 1 1 -0.583311855883158 0.76510478092325 0.364557964026542 45.7181566789195 35.7993509721824 1.27706663493549 0.202504576082508 -37.8678500368547 102.281909574089 -0.370230182390413 0.71145591549117 NABP2 other 1 1 1 1.27706663493549 -0.370230182390413 0.0113840003529846 4.99835473785997 14.2141742731021 0.351645803817003 0.725337534309198 -63.594877498359 24.8893313507331 -2.55510590470266 0.0110822504713905 N4BP2L1 other 1 1 1 0.351645803817003 -2.55510590470266 0.00510467790882564 207.283967895322 77.6392117461135 2.66983606908784 0.00797620504278525 -299.382314966927 221.822089495145 -1.34965059452963 0.178082088415444 SMARCC2 other 1 1 1 2.66983606908784 -1.34965059452963 0.00058099422441799 31.9819534563072 21.2938095909098 1.5019366694234 0.134112056156816 -97.8115064746862 37.2733451541162 -2.62416764769192 0.00910790301966713 BRCA2 ts 1 1 1 1.5019366694234 -2.62416764769192 0.032905560682795 46.3460996096893 26.1327147440319 1.77348966854941 0.0771016168296856 -104.147556989238 66.5575972101413 -1.56477338958638 0.118627494105155 KANSL2 essential 1 1 1 1.77348966854941 -1.56477338958638 0.000391218550326496 131.756518275682 33.780939826663 3.90032127441547 0.000117167923171116 -10.3207742271516 92.1185059354918 -0.1120380114977 0.910863732604514 CERS5 other 1 1 1 3.90032127441547 -0.1120380114977 7.36485307614086e-05 174.841066963201 42.2692376878187 4.13636669424931 4.51764711667213e-05 -76.8114071087404 114.74473841669 -0.669411148333475 0.503717445438859 MAP3K12 other 0.644203698570041 1 0.484156241493753 4.13636669424931 -0.669411148333475 0.035158088398451 -56.7839309177509 25.5848868712943 -2.21943255811153 0.0271625510632686 59.2331001240944 69.0775607600663 0.857486852059446 0.391821653826716 ITGB7 other 1 1 1 -2.21943255811153 0.857486852059446 0.0359324681013921 465.377528534764 190.721282775719 2.44009227371877 0.0152276022769904 -185.095157515669 520.084986076457 -0.355894060530442 0.722155143522276 GALNT6 other 1 1 1 2.44009227371877 -0.355894060530442 0.640873348315531 8.68773579123705 23.7698783695099 0.365493489540989 0.714985294422766 -49.690275867235 64.2030207423246 -0.773955419740517 0.439530351341278 CSAD other 1 1 1 0.365493489540989 -0.773955419740517 0.000135803309788157 60.1898672669924 16.1662470107525 3.72318121991819 0.000232757197821007 -51.2425481171083 41.9770724789848 -1.22072705624629 0.223096601402023 LMBR1L other 1 1 1 3.72318121991819 -1.22072705624629 0.0565123342831256 65.4420913945562 29.9495069316648 2.18508076089113 0.0296124170302882 -42.6002702830972 81.2679198857515 -0.524195406292984 0.600507807364038 C12orf10 other 1 1 1 2.18508076089113 -0.524195406292984 0.00014987317336004 394.408693892692 135.647752790886 2.90759475021094 0.00389664420562768 -964.947840738831 387.557617892758 -2.48981776177044 0.0132881368905658 ESYT1 other 1 1 1 2.90759475021094 -2.48981776177044 5.25158532696656e-05 1846.73853466407 479.665629686128 3.85005391333228 0.000142694784967074 -1928.03449911329 1288.78891710758 -1.49600487210921 0.135641044864064 TMBIM6 other 0.467548641659832 1 1 3.85005391333228 -1.49600487210921 0.0023890141935647 195.177469396014 71.2017409947004 2.74118956459985 0.0064657801627182 -329.757263779622 203.429666632688 -1.62098905846919 0.106004891383529 ANKRD52 other 1 1 1 2.74118956459985 -1.62098905846919 0.235284897041462 -5.81044641619298 11.0708704338107 -0.524840973519818 0.60005829136315 -50.9153577993141 30.0531592586246 -1.69417655432357 0.0912077610990159 KRT71 other 1 1 1 -0.524840973519818 -1.69417655432357 0.625158315384156 13.4096178990234 43.4088376066267 0.308914466232477 0.757588245664638 -97.7735161325469 117.248328238539 -0.833901153231191 0.404960673516953 ZNF740 other 1 1 1 0.308914466232477 -0.833901153231191 9.47796644444091e-22 252.591123755969 34.5452234170917 7.31189723992339 2.17756681435391e-12 -280.038948328609 63.8631861310165 -4.38498241779081 1.5817111567735e-05 WDFY2 other 1.39136547404393e-17 0.231657416021047 3.0438028931039e-08 7.31189723992339 -4.38498241779081 0.0679365105687057 -111.458334751387 47.8990860332217 -2.32694074108391 0.0206021232657935 -84.3442176448565 89.0608746572093 -0.947040077581688 0.344344280520883 HNRNPA1L2 other 1 1 1 -2.32694074108391 -0.947040077581688 0.0299576831517975 27.8806990552727 48.9783517132945 0.56924535187461 0.569591496162348 -196.757200815293 91.4271121940006 -2.15206623170806 0.032144536341228 LPAR6 other 1 1 1 0.56924535187461 -2.15206623170806 1.05881496661245e-25 352.135389858963 46.7208949968245 7.53700009134878 5.08500727834718e-13 -457.985303848129 87.7803638991277 -5.21740037868173 3.28493685479511e-07 ESD other 1.58292837508562e-21 0.00494875737174884 7.15969024791284e-09 7.53700009134878 -5.21740037868173 1.20883995269153e-09 315.297569387642 91.9232743409371 3.43000803276682 0.000683182568359695 -652.292755003962 171.591718022792 -3.80142330014622 0.000172426915193246 RB1 ts 1.45580595502641e-05 1 1 3.43000803276682 -3.80142330014622 0.22849034070742 15.3753241848168 13.7013815392962 1.12217327433147 0.262630072324004 -40.6116817619659 36.0623360105759 -1.12615227560566 0.260944911230786 MORN3 other 1 1 1 1.12217327433147 -1.12615227560566 0.00187022912301722 82.6228796844183 46.1703123947959 1.78952394729153 0.074476000828388 -340.427079707623 121.521272473076 -2.80137849760458 0.00539821861710543 SETD1B other 1 1 1 1.78952394729153 -2.80137849760458 7.64163283955862e-06 109.53446743146 23.5189518141378 4.65728525221162 4.70388867535793e-06 -54.2779484787074 61.4050361159704 -0.883933174083594 0.377395909603127 VPS33A other 0.0737417569017406 1 0.0539206758856279 4.65728525221162 -0.883933174083594 0.00937688180954854 120.512657771367 77.7325327836415 1.5503503289517 0.122048953704269 -478.347215028029 200.38410094621 -2.38715153931516 0.0175616183322425 VPS37B other 1 1 1 1.5503503289517 -2.38715153931516 0.00298335473720553 208.798069579084 62.4915276213851 3.34122204283627 0.000932828245839856 -52.8173604579692 164.479068073039 -0.321119040111019 0.748329806217771 RHOF other 1 1 1 3.34122204283627 -0.321119040111019 1.19080597135974e-06 220.046351419309 49.0111672182404 4.48971864798631 9.96674255841025e-06 -271.80538237216 125.790782620856 -2.16077344229112 0.0314545663245757 DENR essential 0.0122641106990339 1 0.111886651960713 4.48971864798631 -2.16077344229112 1.33479027931373e-07 60.7215494166691 19.3520102254689 3.13773859713831 0.00186404203310917 -120.011685335572 36.293118278461 -3.30673392169765 0.00105335172601463 DIAPH3 other 0.00146239623001612 1 1 3.13773859713831 -3.30673392169765 0.591995751890803 -3.38755501602876 5.61381484206445 -0.603431910622654 0.546686656678354 7.29857683309617 11.4946134207749 0.634956267420446 0.525950767951458 SLAIN1 other 1 1 1 -0.603431910622654 0.634956267420446 7.23694945796739e-13 213.621589956058 32.5145594373561 6.57002873951376 2.30430831581876e-10 -143.48037740263 65.2882453356576 -2.19764486953163 0.0287594842998596 RBM26 other 9.5636287087039e-09 1 3.10828148720793e-06 6.57002873951376 -2.19764486953163 2.94052015058187e-12 313.033347790736 49.3334068580152 6.34526110656955 7.74720321871368e-10 -292.051737936307 114.778642708202 -2.5444780583334 0.0114226769720822 MBNL2 other 3.83120370419312e-08 1 1.03425162969828e-05 6.34526110656955 -2.5444780583334 0.132567098808076 15.6302879850176 7.80418722227335 2.00280792090795 0.0460572462168345 4.4591482218597 18.1500526440472 0.245682385021742 0.806088614304529 ZIC5 other 1 1 1 2.00280792090795 0.245682385021742 2.57365199323961e-25 111.834422191282 10.4602545006721 10.6913672305102 5.62013326380931e-23 -49.9479165652454 24.8422847717756 -2.01060075689951 0.0452168729201943 ABHD13 other 3.84194769550809e-21 1 8.43019989571397e-19 10.6913672305102 -2.01060075689951 0.00234309084031379 37.9091088381982 10.8002704055609 3.51001478802597 0.000512993628313649 25.1911781700228 26.4170083523699 0.953596933990557 0.341014277134879 RAB20 other 1 1 1 3.51001478802597 0.953596933990557 4.29121335264112e-06 63.9418378392052 14.9841881790921 4.26728742825223 2.62288216870618e-05 -61.7190837838929 36.742340191158 -1.67978096829949 0.0939945538223225 GRTP1 other 0.042281325163573 1 0.285972842854035 4.26728742825223 -1.67978096829949 1.96396825572686e-32 536.068003174478 42.4450946642234 12.629680942291 7.27676970255722e-30 -213.47520423382 103.874606661801 -2.05512406828032 0.0406913139294704 CUL4A other 2.97776866933307e-28 1 1.10512301472736e-25 12.629680942291 -2.05512406828032 0.00744195912229269 49.3789717330197 17.4956218752273 2.82236162196311 0.00506541181081565 -35.8685606230119 48.1573627677806 -0.74481986889468 0.456927272299562 CDH24 other 1 1 1 2.82236162196311 -0.74481986889468 0.11047919223195 6.71410393922532 4.98457107687802 1.34697726959298 0.178940660313849 -16.8409580708363 13.5389420009351 -1.24389025890451 0.214450367229161 CBLN3 other 1 1 1 1.34697726959298 -1.24389025890451 0.753256647121114 -1.07233108874932 4.2094340060792 -0.254744720359239 0.799086503072268 -8.4440577370894 11.267770188897 -0.749399179742768 0.454175921985066 NOVA1 other 1 1 1 -0.254744720359239 -0.749399179742768 0.814516437589437 1.49756588666741 16.0981199381696 0.0930273778813506 0.925940208231646 27.8848392312494 43.7318884474371 0.63763171958067 0.524170839713136 FITM1 other 1 1 1 0.0930273778813506 0.63763171958067 2.63141312145677e-15 329.708829761389 42.3798569792487 7.77984762720722 1.03936269496589e-13 -256.31575273752 129.255157910996 -1.98302146606805 0.048230523497108 TMX1 other 3.63424466204395e-11 1 1.47901311493647e-09 7.77984762720722 -1.98302146606805 3.76286571146945e-13 842.815160951385 115.803659868471 7.27796653325682 2.70168478414381e-12 -513.191743690755 353.191855987142 -1.45301126000323 0.147212922129495 FRMD6 other 5.0000959574006e-09 1 3.77155195866476e-08 7.27796653325682 -1.45301126000323 0.0173427745270031 42.9467954235193 18.8264280548462 2.28119722437014 0.0231955856442576 127.543630783936 57.7705128086918 2.20776352126731 0.0279720376555055 PELI2 other 1 1 1 2.28119722437014 2.20776352126731 0.0540972745086251 -3.97834823961003 8.81073336815146 -0.451534290436111 0.651911340669262 61.4581266831755 27.8629339382457 2.20573062475721 0.0281155755284484 RTN1 other 1 1 1 -0.451534290436111 2.20573062475721 8.74955921082222e-05 27.7512855719786 6.73147401052165 4.12261646239767 4.78145428621384e-05 49.6860444767521 20.7903443854736 2.38986154127722 0.017434896678876 C14orf37 other 0.75841179239407 1 0.511328721367708 4.12261646239767 2.38986154127722 7.3260429633416e-06 11.7758069445336 2.56357847263429 4.59350360062629 6.30415943523728e-06 24.1906490229915 8.5066400047388 2.84373724637643 0.0047493316815353 SYT16 other 0.0707915531547698 1 0.0717539426918708 4.59350360062629 2.84373724637643 3.57159748235886e-10 35.7898980645876 5.30146700858327 6.75094233476177 6.94692097095523e-11 10.2763374726133 17.4944773772067 0.587404656397577 0.557347502794432 SLC38A6 other 4.39306490330139e-06 1 9.4658745150236e-07 6.75094233476177 0.587404656397577 2.18721879750786e-24 185.269624604008 16.8241600245429 11.0121173558584 4.0563490227718e-24 -19.7269528130021 51.9618853701047 -0.379642745302535 0.704463235965469 NAA30 other 3.25108202061568e-20 1 6.09953202554195e-20 11.0121173558584 -0.379642745302535 0.00149474113146334 101.573449953979 38.8504992523822 2.61446961837306 0.00936343537516544 -224.693655595338 122.884746150091 -1.82849102622466 0.0684154365994628 RDH12 other 1 1 1 2.61446961837306 -1.82849102622466 4.21174045104279e-26 373.877329359389 33.9438731659496 11.0145747814789 4.17203437019609e-24 -193.920737546773 108.550504325971 -1.78645634813857 0.0749809660257043 DCAF5 other 6.30244841094043e-22 1 6.27307087902683e-20 11.0145747814789 -1.78645634813857 0.0139883191720936 80.6949790185423 27.6439030123021 2.91908776349821 0.00376184658337971 31.6600329647414 92.4572198700564 0.342428995910085 0.732255001459567 RAB15 other 1 1 1 2.91908776349821 0.342428995910085 1.13921178201267e-25 75.2910764872521 6.6743810950488 11.2806079567594 5.00204601692972e-25 -12.7365761009527 22.0972994029765 -0.576386094458089 0.564764551686945 WDR89 other 1.70277985057433e-21 1 7.536582733708e-21 11.2806079567594 -0.576386094458089 0.0659736284630933 3.39864835090585 1.62394975219175 2.09282851659597 0.0371642455839994 8.16540647886743 5.37791883700574 1.51832088329055 0.129936508173469 ESR2 other 1 1 1 2.09282851659597 1.51832088329055 2.84171049006609e-17 508.397937215685 64.6969383782158 7.85814522232275 6.17272828876634e-14 -547.226875098949 194.175723740076 -2.81820437981974 0.00513368944410059 STON2 other 4.01817863295345e-13 1 8.80539690392518e-10 7.85814522232275 -2.81820437981974 0.225410058442202 -0.0960045707080428 5.63400242307871 -0.0170402075644797 0.986415225528366 -27.4838016328203 16.552394070054 -1.66041247667871 0.0978171648608344 EFCAB11 other 1 1 1 -0.0170402075644797 -1.66041247667871 0.00102541365113011 -11.3745923156471 3.14223837046105 -3.61990115790553 0.000342947433679211 -0.991934842353515 9.16751906780232 -0.108201012184129 0.913904694910781 GPR65 other 1 1 1 -3.61990115790553 -0.108201012184129 0.00416976715438733 25.9278140726052 7.77822812977668 3.33338308416902 0.000958596203672889 14.1849867007307 24.1299148622834 0.587858961860771 0.55704157568627 PTGR2 other 1 1 1 3.33338308416902 0.587858961860771 3.04812720181823e-05 93.0094190875418 20.9257086138668 4.44474406118354 1.21581803126936e-05 -16.8605261469875 68.388438987924 -0.246540590727107 0.805422359090668 JDP2 other 0.278446419886095 1 0.13563665956841 4.44474406118354 -0.246540590727107 0.934131328683477 -2.82063297809791 9.14145265012295 -0.30855413095204 0.757862750273013 -7.56985884945538 27.0783491523639 -0.279553927267185 0.780001496946736 AK7 other 1 1 1 -0.30855413095204 -0.279553927267185 0.843136851477407 15.4380655833414 27.5472767122031 0.560420753914398 0.575585846943316 26.1088328704715 81.2537607867374 0.321324608457177 0.748174836641943 FBLN5 other 1 1 1 0.560420753914398 0.321324608457177 0.161519612323386 -388.078833020837 1275.34650456402 -0.304292858162106 0.761105707851174 -7299.54220227051 3843.89991567533 -1.89899382460588 0.0584787989687957 WARS essential 1 1 1 -0.304292858162106 -1.89899382460588 1.06117031821623e-20 85.5108418309126 9.52080423773261 8.98147254115553 2.46427255838595e-17 -60.642473838582 28.3370850790631 -2.14003923372442 0.0331170500861211 WDR20 other 1.54803526021383e-16 1 3.60523075291865e-13 8.98147254115553 -2.14003923372442 1.09543605719485e-06 123.58762337371 40.9889593126994 3.01514421068553 0.00277879833329764 -261.875190045363 89.3765577330353 -2.93002098858601 0.00363859424011279 NIPA2 other 0.011311472726594 1 1 3.01514421068553 -2.93002098858601 0.000361047021953914 -61.5397159988685 112.498508722305 -0.5470269490485 0.584745090812332 -915.505822391196 234.866474331433 -3.89798426956108 0.00011839542450112 SLC12A6 other 1 1 1 -0.5470269490485 -3.89798426956108 0.0463692563095959 147.456966476467 109.969224406326 1.34089302959551 0.180909193896971 -321.773158950829 221.404790219883 -1.45332519062152 0.147116507898383 DUOXA1 other 1 1 1 1.34089302959551 -1.45332519062152 2.24077165715721e-11 66.696856619577 26.7175238901592 2.49637117922231 0.0130498211748649 -287.923380859953 54.0948347655085 -5.32256697165358 1.92894355831362e-07 MFAP1 essential 2.85743201720688e-07 0.00291019714642776 1 2.49637117922231 -5.32256697165358 0.000817056167564823 227.860969067265 66.935264115834 3.40419914789524 0.000748303480258556 -45.0214118366102 132.153659805218 -0.340674725943781 0.733572714870202 TCF12 other 1 1 1 3.40419914789524 -0.340674725943781 0.0223700121114534 133.647346026393 82.7013414163973 1.61602392098437 0.107077642606597 -249.060434736193 166.505431370006 -1.49580967231474 0.135691900461954 SORD other 1 1 1 1.61602392098437 -1.49580967231474 0.000610047138811774 958.260395402005 541.768852202747 1.76876243716461 0.0778861172714661 -2744.91661923703 1096.91664023556 -2.50239308854642 0.0128341901239127 SERF2 other 1 1 1 1.76876243716461 -2.50239308854642 1.3557633821557e-08 93.1155683604964 20.0626036696592 4.64125045251806 5.05911253153856e-06 -79.832688024836 40.6206516344069 -1.96532268224903 0.0502415171060373 ZSCAN29 other 0.000156292402694909 1 0.0579369567111796 4.64125045251806 -1.96532268224903 0.301001394425815 -5.07928260031232 56.1053030327258 -0.0905312390408019 0.92792188808881 -166.428644570373 112.958720180525 -1.47335809315469 0.1416405446991 DUOXA2 other 1 1 1 -0.0905312390408019 -1.47335809315469 0.578059431511519 -287.41813238168 305.828566330271 -0.939801457497895 0.348030480354017 -479.264423485426 615.735083494012 -0.778361403033626 0.436932933379781 DUOX2 other 1 1 1 -0.939801457497895 -0.778361403033626 0.000572329013623983 9.99315870960549 12.3104698736707 0.81176094918835 0.417539857716726 -85.1700235043478 25.6361789832496 -3.3222588888928 0.000997654084596287 LYSMD2 other 1 1 1 0.81176094918835 -3.3222588888928 0.196038975139468 -25.7356735112025 19.6475925498663 -1.30986396658442 0.191187315680658 29.4461790283683 41.9711672682843 0.701581131640801 0.483453542514475 SLC27A2 other 1 1 1 -1.30986396658442 0.701581131640801 0.395095165004738 20.1259492663936 17.7203046543338 1.13575639126901 0.256916473700181 -10.9238939884091 36.0439298324871 -0.303071669464942 0.762034036444471 FGF7 other 1 1 1 1.13575639126901 -0.303071669464942 0.0995116757414431 -6.62855333417289 6.23813828644972 -1.06258518644436 0.288778913615039 18.5416590755035 13.3607552896516 1.38777027746813 0.166181679639677 HDC other 1 1 1 -1.06258518644436 1.38777027746813 0.499907430614809 66.3384753462126 74.9730047074868 0.884831488414229 0.376913965081803 155.115038243465 148.310770034087 1.04587844974316 0.2964089985306 GCNT3 other 1 1 1 0.884831488414229 1.04587844974316 6.80584619538834e-09 192.79697421744 46.2348241983135 4.16995149349942 3.93036254425401e-05 -267.132288389731 91.4612186879281 -2.92071647657795 0.00374115987400515 BNIP2 other 7.9601177101262e-05 1 0.423142831514386 4.16995149349942 -2.92071647657795 0.00531443222825123 102.207222302204 42.2548035368216 2.41883084873744 0.0161297927712249 -97.7374877856769 83.5879857641515 -1.1692767434479 0.243165105064371 GTF2A2 essential 1 1 1 2.41883084873744 -1.1692767434479 8.15901300322294e-08 347.64750889321 119.48957156576 2.90943807344632 0.00387514532901535 -838.085895964908 238.810654481805 -3.50941584990615 0.000513681606432121 SRP14 essential 0.000904508181537295 1 1 2.90943807344632 -3.50941584990615 1.40290131736773e-05 86.6848396954915 36.4995077190538 2.37495914637335 0.0181418315275277 -208.092103982915 72.8729089391299 -2.8555482004531 0.00457783343026398 BAHD1 other 0.132209420148735 1 1 2.37495914637335 -2.8555482004531 0.00788922676427621 55.9206281309451 18.1421249261488 3.08236374507294 0.00223220295755322 25.4790117711909 36.2859111810159 0.702173679588375 0.483081275846751 DISP2 other 1 1 1 3.08236374507294 0.702173679588375 8.39516299538637e-10 52.9647934187196 14.4297079872878 3.67053813323043 0.000283494858460367 -108.351136042024 29.2157563888014 -3.70865414538969 0.000245557524510895 CDAN1 essential 1.01850117460027e-05 1 1 3.67053813323043 -3.70865414538969 0.0127322051791308 156.980555170523 99.0088005731514 1.58552122904003 0.113835624199796 -338.473326262122 192.693330418399 -1.75653887722625 0.0799529116618706 TLE3 other 1 1 1 1.58552122904003 -1.75653887722625 2.96666059192919e-06 222.044495151599 90.3464229618128 2.45770101208602 0.0145128340636426 -580.420424001544 175.834400892863 -3.30094919455037 0.00107241180676747 ANP32A other 0.0296013393862695 1 1 2.45770101208602 -3.30094919455037 0.00332167690788788 -53.0178081484919 85.6726652396019 -0.618841587339629 0.536460997808615 -550.70490206919 164.74467685557 -3.34277812540181 0.000927790460006181 COMMD4 other 1 1 1 -0.618841587339629 -3.34277812540181 1.38205071909595e-05 315.376593950435 70.4469275738088 4.47679699898918 1.05512085188768e-05 0.486105774558128 136.989311105366 0.00354849419006302 0.9971709283043 UBE2Q2 other 0.130327382810748 1 0.118162984202902 4.47679699898918 0.00354849419006302 0.0809908693937234 -9.15589903939849 13.8873391945253 -0.659298294017903 0.510179889017853 -60.384720151174 26.9233184306116 -2.24284091527577 0.0255934315518755 PSTPIP1 other 1 1 1 -0.659298294017903 -2.24284091527577 3.99138358629628e-08 321.995368374141 70.8713319461771 4.54337966469544 7.86362018668965e-06 -272.240575053754 137.614706940696 -1.9782811089448 0.048757047262077 ETFA other 0.000449629360996276 1 0.0889296806912733 4.54337966469544 -1.9782811089448 0.248920578727529 -43.0842013115097 34.7696672573779 -1.23913182696241 0.21620759723492 -101.478531968339 68.0291575451111 -1.4916917338135 0.136768202834653 BCL2A1 other 1 1 1 -1.23913182696241 -1.4916917338135 3.53472360684429e-05 84.7463987708619 24.2766565263746 3.4908595703363 0.000549066694322219 -69.5452166726372 47.0991921862443 -1.47656920309025 0.140774534926074 HMG20A other 0.320458042196503 1 1 3.4908595703363 -1.47656920309025 0.00762237979769463 66.2055976334214 25.4127625336806 2.60521057266704 0.00961198484459709 -32.859762466252 49.2676018286876 -0.666964927185038 0.505276669643189 SCAPER other 1 1 1 2.60521057266704 -0.666964927185038 0.04638579511482 227.901798363453 163.917260521159 1.39034655434615 0.165392931916301 -444.472137738045 317.785613173794 -1.39865405893931 0.162888193564577 TSPAN3 other 1 1 1 1.39034655434615 -1.39865405893931 0.00127893433545055 98.7529832844608 37.446718329885 2.63715988179528 0.00876843663862119 -102.218835171559 72.6504566824219 -1.4069950808209 0.160399333322445 WDR61 essential 1 1 1 2.63715988179528 -1.4069950808209 0.00195242914031581 103.442158200594 35.6429987090583 2.9021732723713 0.00396540893850141 -278.382391461676 165.804826410496 -1.6789764055026 0.0941420054734805 NCOA2 other 1 1 1 2.9021732723713 -1.6789764055026 0.0167185897302218 8.20880898147534 28.3762492297837 0.289284496869282 0.772551004062089 -139.302865314728 54.5662493008671 -2.55291259889681 0.0111464055656327 NEIL1 other 1 1 1 0.289284496869282 -2.55291259889681 0.201447784923185 66.5572554327413 72.4292800437842 0.918927475083374 0.358825639000854 -152.691643972398 140.520197951779 -1.08661705717776 0.278023907788202 DNAJA4 other 1 1 1 0.918927475083374 -1.08661705717776 0.100052245322742 1146.36562943904 541.743738852991 2.11606622693266 0.0351111275185394 418.216741264866 1058.23523226053 0.395202057647903 0.69295708468846 TPM1 other 1 1 1 2.11606622693266 0.395202057647903 5.2088494950791e-20 1225.56913483799 126.501952570046 9.68814401627027 1.26161115681491e-19 -181.126228419331 347.911032638791 -0.520610763750572 0.602999101812665 IGF1R other 7.55751973241026e-16 1 1.86882460658993e-15 9.68814401627027 -0.520610763750572 0.00942835667519637 237.645039550467 82.6194853562167 2.87638005158047 0.0042926294705558 -72.3981393015785 209.686235204669 -0.345268916821901 0.730119055608927 ARRDC4 other 1 1 1 2.87638005158047 -0.345268916821901 0.0482693588290908 -12.3329492282585 15.2132502368368 -0.810671555141842 0.418156804535575 -73.6679628796628 29.7930817102938 -2.47265333596591 0.0139307400087049 PIF1 other 1 1 1 -0.810671555141842 -2.47265333596591 0.00143237135822229 78.3800716540419 28.4488875870289 2.75511903283624 0.00620301179669458 -70.7169468910882 55.6696307492139 -1.270296675932 0.204901801256943 USP3 other 1 1 1 2.75511903283624 -1.270296675932 0.277901697388519 13.5239136635923 12.6440391394719 1.06958808925019 0.285610881726704 -17.2098697347151 24.8426168984736 -0.692755912352074 0.488965177886064 CYP11A1 other 1 1 1 1.06958808925019 -0.692755912352074 0.075908996418655 3.33268260524032 13.0735525031711 0.254917904252265 0.798950258240644 -51.8813382020035 25.7759540190246 -2.0127805226418 0.0449750246349062 BBS4 other 1 1 1 0.254917904252265 -2.0127805226418 5.29345996368607e-05 477.855991737729 275.275789614028 1.73591725014301 0.0835410163340912 -1718.76675393885 540.442631715038 -3.18029454575878 0.00161531000329713 PML other 0.471012067568786 1 1 1.73591725014301 -3.18029454575878 0.916293979845706 -3.48920794903489 13.9146499539264 -0.250757867469768 0.802162247513381 5.81833222401822 27.3390737143982 0.212821117672102 0.831602001608746 CYP1A1 other 1 1 1 -0.250757867469768 0.212821117672102 0.370555544560228 15.4083233337471 10.9461966727999 1.40764174026172 0.160207823040402 7.66406539499506 30.7964189628841 0.248862226619004 0.803627001400187 ADAMTS17 other 1 1 1 1.40764174026172 0.248862226619004 1.54590708368191e-10 70.4211058466219 12.283335599665 5.7330604765486 2.28146939160964e-08 -58.141786800341 27.2005806727126 -2.13752005885184 0.0333132808903438 LINS1 other 1.92233545855846e-06 1 0.000291206753145054 5.7330604765486 -2.13752005885184 0.00146476257809473 83.7310069411429 44.3757369938632 1.88686459343137 0.0600835967115496 -188.421859845963 87.1880750736125 -2.16109668308285 0.0314293716454635 ULK3 other 1 1 1 1.88686459343137 -2.16109668308285 7.05540912981821e-08 184.920292269017 33.214019428332 5.5675373065892 5.48753003102872e-08 -17.7226341331092 73.5318902452377 -0.241019700078456 0.809694684181906 PCSK6 other 0.000783997062505399 1 0.000690386153203724 5.5675373065892 -0.241019700078456 0.0592578876459572 25.6837629468281 14.5204087453178 1.76880440470452 0.0778790972992915 -22.9945424097876 28.5075848003224 -0.806611383280972 0.420489477660298 CCDC33 other 1 1 1 1.76880440470452 -0.806611383280972 0.000854405307803889 11.9756240367016 4.15219744984056 2.88416535614448 0.00419057445120885 -10.1529040434447 8.18651629073593 -1.24019835579317 0.215810634788129 CELF6 other 1 1 1 2.88416535614448 -1.24019835579317 9.79380880743077e-10 448.526290767329 101.435640345317 4.42178202099788 1.34286545188886e-05 -577.32846819435 199.297607762334 -2.89681584579191 0.00402945037830181 SCAMP2 other 1.18416942290645e-05 1 0.149353495559078 4.42178202099788 -2.89681584579191 0.0202977871394675 -129.078902582774 59.6605138925636 -2.16355666689728 0.031238199919142 -281.393077229513 120.504462476657 -2.33512578244994 0.02015469251299 HAPLN3 other 1 1 1 -2.16355666689728 -2.33512578244994 0.398269763338419 733.692541911936 1745.6471614714 0.420298304322569 0.674549632917327 -4007.56280499745 3581.96077526194 -1.11881817150954 0.264056859216023 RHCG other 1 1 1 0.420298304322569 -1.11881817150954 3.00557994829288e-07 266.286060469647 58.8523535154855 4.52464590731414 8.5382920647039e-06 -228.446886431757 120.761415294618 -1.89172084373492 0.0594309262925529 POLG other 0.00322739174847689 1 0.0963717025343129 4.52464590731414 -1.89172084373492 0.00350595474590604 129.884891261814 97.2922479858141 1.33499732970249 0.18282618219893 -520.80815072635 199.637718156341 -2.60876629695043 0.00951344183107566 FANCI other 1 1 1 1.33499732970249 -2.60876629695043 0.705270199294082 206.415586064911 308.930716774032 0.66816141891094 0.504512196489531 -184.680829183527 633.906859405315 -0.291337483485793 0.770981975780994 ABHD2 other 1 1 1 0.66816141891094 -0.291337483485793 0.00465807995619838 67.4411158375863 31.6835203870838 2.12858656530729 0.0340520651668354 -119.463852578925 65.6724815798313 -1.81908540236454 0.0698328847775809 TICRR other 1 1 1 2.12858656530729 -1.81908540236454 0.373471407122322 -21.5892055378896 16.9041673516524 -1.27715285164751 0.202474179929806 -32.2741421925387 34.4890013571872 -0.935780710444175 0.350091752281821 NTRK3 other 1 1 1 -1.27715285164751 -0.935780710444175 0.191518799043412 3.46644324561503 4.58019591223344 0.756832963488824 0.449706803812503 -12.765328437384 9.30177032876551 -1.37235472240242 0.170914188046194 DET1 other 1 1 1 0.756832963488824 -1.37235472240242 0.895986459090024 13.929429006297 161.194465936557 0.0864138165374692 0.931191508511888 -135.704715263637 325.586408908184 -0.416800921508691 0.677103478583739 MFGE8 other 1 1 1 0.0864138165374692 -0.416800921508691 2.24187343214768e-07 136.251086751726 28.8649361995437 4.72029751979428 3.53097865971018e-06 -99.5492870881558 59.8241549355198 -1.66403164734133 0.0970880602454907 ZNF710 other 0.00242637961561343 1 0.0408145823275899 4.72029751979428 -1.66403164734133 1.59502413603566e-15 597.895238196324 81.7634129860546 7.31250343351372 2.11805695499909e-12 -403.802394168874 169.13042062544 -2.3875207823384 0.0175424760786211 UNC45A essential 2.21054395013182e-11 1 2.96104362308873e-08 7.31250343351372 -2.3875207823384 0.244315496360273 15.213241179577 9.07182177748317 1.67697751926048 0.0945264546790464 7.10578595839802 18.8534282858635 0.376896225485208 0.706501313916538 ST8SIA2 other 1 1 1 1.67697751926048 0.376896225485208 0.0058459195741651 57.8110758035393 23.9140105517486 2.41745631408999 0.0161914835965159 -68.2717004789386 50.5074563661582 -1.35171527910645 0.177427099720796 MCTP2 other 1 1 1 2.41745631408999 -1.35171527910645 1.90506322996452e-05 891.807072256278 238.697851108989 3.73613364390567 0.000221346597114864 -858.546985153486 494.714318050198 -1.73543993741125 0.0836286118167904 FURIN other 0.177151829754401 1 1 3.73613364390567 -1.73543993741125 3.53443543910724e-07 1768.74816532626 366.145172794455 4.83072916632221 2.11314316722536e-06 -990.738143551512 758.932777106755 -1.30543596671165 0.192682233894699 IQGAP1 other 0.0037836131375643 1 0.0247301144860383 4.83072916632221 -1.30543596671165 2.60394464878765e-05 174.42091251677 40.7875055642237 4.27633193312417 2.5113134946252e-05 -49.7597093105564 84.5429003825511 -0.588573482638955 0.556562627016754 CRTC3 other 0.239224394884121 1 0.274084754803394 4.27633193312417 -0.588573482638955 1.08107080256956e-10 136.154230028334 27.7682326433237 4.90323715510461 1.51044001812378e-06 -164.065016127837 54.6747543820389 -3.00074537109825 0.00290759899918256 EFL1 other 1.3497168970081e-06 1 0.0178398070540599 4.90323715510461 -3.00074537109825 0.00689781734016467 18.4678241003236 9.03502157609257 2.04402656316738 0.0417822433220063 53.2599618409293 17.8213333237891 2.98855090543839 0.00302351391356203 SH3GL3 other 1 1 1 2.04402656316738 2.98855090543839 2.4112397840869e-08 290.437008695322 62.7002275593505 4.63215238605635 5.27199705085559e-06 -285.311297687793 122.867005844972 -2.32211484056009 0.0208539932968713 SEC11A other 0.000274953672579429 1 0.0602958302706354 4.63215238605635 -2.32211484056009 4.59145640727441e-08 119.32786175796 56.8832599711369 2.0977676353027 0.0367121694603839 -811.143685262541 168.024681145266 -4.82752700218645 2.14786805914386e-06 GLYR1 other 0.00051534506715248 0.0320333042340716 1 2.0977676353027 -4.82752700218645 9.51675680551664e-08 192.230629597783 38.514945494473 4.99106586105305 9.93890133491838e-07 -208.60408904175 123.048449082535 -1.69530043326128 0.0910034796739769 PMM2 other 0.00105226779998597 1 0.0118531337320237 4.99106586105305 -1.69530043326128 4.61433429099099e-08 238.445481899681 40.6304660782937 5.86863762380189 1.1316395822375e-08 72.880545424734 141.982534549459 0.513306412341486 0.608103801799646 SLC5A2 other 0.000517820594135008 1 0.000145936240525348 5.86863762380189 0.513306412341486 0.744901840606484 3.05297844553394 39.4296173961307 0.0774285587116433 0.938332572585301 -96.2422738300976 135.508280521437 -0.710231680748633 0.478094409816675 ITGAX other 1 1 1 0.0774285587116433 -0.710231680748633 0.00259608325258048 137.898501721625 39.6241831979974 3.48016010910716 0.000573207390510306 153.247376203328 138.466094606514 1.10675018775404 0.269262797771824 TGFB1I1 other 1 1 1 3.48016010910716 1.10675018775404 1.15677624878591e-07 307.39396368781 54.0818144693686 5.68386927664779 3.07039129984446e-08 79.0768177616087 188.774682002228 0.418895250797856 0.675586566392903 C16orf58 other 0.00127199116316498 1 0.00039006251073224 5.68386927664779 0.418895250797856 0.00577035419749648 50.3865279027205 28.0546449185657 1.7960137456374 0.0734691164393003 -206.418865042683 98.0365222428762 -2.10553026892671 0.0360518995075193 ARMC5 other 1 1 1 1.7960137456374 -2.10553026892671 9.04238135160098e-10 168.011602905872 31.6672397674679 5.30553354632672 2.10202332907014e-07 -261.654993209638 99.8222463949187 -2.62120922599231 0.00918024330968493 PARN other 1.09530365311943e-05 1 0.00258422748075883 5.30553354632672 -2.62120922599231 1.37977447780608e-11 182.814375418408 32.7085109012819 5.58919896934971 4.91022323798343e-08 -145.425486058736 86.5492650657518 -1.68026251809597 0.0938882605495877 FTO other 1.76749110606959e-07 1 0.000618982741380191 5.58919896934971 -1.68026251809597 2.56195673457938e-06 457.228004892685 122.398614294121 3.73556520659603 0.000221826084533234 -918.183602866943 375.570437252058 -2.44477070555668 0.0150351795995919 UQCRC2 essential 0.0256836162641583 1 1 3.73556520659603 -2.44477070555668 0.0427924796113692 -46.5205295265301 18.5037540655675 -2.51411304763811 0.0124251361613961 -50.8368330547121 55.9237406642337 -0.909038495116709 0.364016081490562 IGSF6 other 1 1 1 -2.51411304763811 -0.909038495116709 1.53652107668998e-09 128.220804947962 27.1050147878923 4.73051964558375 3.37715451115108e-06 -269.983946776431 95.0460275781477 -2.84056002818685 0.0047947547077678 ARHGAP17 other 1.84305703148963e-05 1 0.0390804320030403 4.73051964558375 -2.84056002818685 0.148359761264216 64.8330766911098 36.9811206728313 1.75313985924554 0.0805826127801048 1.13532640635707 99.9685901501626 0.0113568312272054 0.990946179319635 MYLK3 other 1 1 1 1.75313985924554 0.0113568312272054 0.00126633162929489 64.1762989522247 18.7969245859329 3.41419143641469 0.000723971210467405 16.8151762956134 49.806911735959 0.337607286007924 0.735885450442142 NKD1 other 1 1 1 3.41419143641469 0.337607286007924 3.79842000841889e-27 302.056745409183 35.6328350925133 8.47692148617854 8.69382018471804e-16 -436.594397212638 97.7757200511545 -4.46526394266613 1.11114935799599e-05 DHX38 other 5.70218811663844e-23 0.16336117861257 1.25982148296749e-11 8.47692148617854 -4.46526394266613 1.27068936958855e-06 27.172484470816 10.2312661654855 2.65582812833866 0.00830884099068394 -87.3088551623366 28.0743705564855 -3.10991318529018 0.0020402583498435 TXNL4B other 0.0130601453406311 1 1 2.65582812833866 -3.10991318529018 0.00108594443042226 32.8061014563372 19.1642251899704 1.71184074133643 0.0878948949963333 -123.537588334018 52.6842848244473 -2.34486600218007 0.0196447236666771 MARVELD3 other 1 1 1 1.71184074133643 -2.34486600218007 0.00407396856350905 118.961655671007 36.0005947857029 3.30443583999482 0.00106030064817295 87.3728161320149 98.9504629449022 0.882995526566319 0.377905704864138 ZFHX3 other 1 1 1 3.30443583999482 0.882995526566319 0.136652484560501 4.04594334291151 2.18884777929191 1.84843522751517 0.0654618250939547 8.63709375721346 5.75372140051519 1.50113172953423 0.134307539265276 CLEC18B other 1 1 1 1.84843522751517 1.50113172953423 3.15243603590114e-06 196.849382361427 42.0865631961796 4.67725011053637 4.295057770391e-06 23.3729685506364 111.814531453818 0.209033372020076 0.834555188050044 CPNE2 other 0.0313982629175754 1 0.0493630989551037 4.67725011053637 0.209033372020076 0.0133986027905549 14.6890736554388 105.704333758085 0.138963778808315 0.889566457793539 -728.772055225375 281.950195326793 -2.58475456766645 0.0101886066590566 NLRC5 other 1 1 1 0.138963778808315 -2.58475456766645 1.70909499652629e-12 114.042343299996 28.1690088938477 4.04850393316124 6.47541723631976e-05 -297.318237874723 74.1440975912706 -4.01000548302213 7.56698604697077e-05 KATNB1 essential 2.24011081194701e-08 1 0.684257339361909 4.04850393316124 -4.01000548302213 2.47034073370579e-10 282.087732139638 75.8306972859212 3.71996753604969 0.000235371694258442 -699.035121966088 199.595187788428 -3.50226440683063 0.000527139845689756 KIFC3 other 3.05581148759406e-06 1 1 3.71996753604969 -3.50226440683063 0.000637567978265646 10.7272252822551 4.23905340931843 2.53057091912883 0.0118682442650108 -16.3794987982465 11.0523089932887 -1.48199790724207 0.139327991198125 NUDT7 other 1 1 1 2.53057091912883 -1.48199790724207 8.07808614651893e-05 26.6630925468852 7.75024249935973 3.44029139076461 0.000658391538355323 -17.3190487419165 19.7978953467906 -0.874792418009425 0.382345007140389 GCSH other 0.702784421438508 1 1 3.44029139076461 -0.874792418009425 0.00164440541654403 156.334741429912 43.4115559338056 3.60122409959903 0.00036700210948567 206.136392218428 115.098111113143 1.79096242522862 0.0742443405608782 CMTM3 other 1 1 1 3.60122409959903 1.79096242522862 0.0142272274996107 430.223969435806 147.082561244171 2.92505084081039 0.00369001889810346 389.192453522506 389.497238759829 0.999217490634097 0.318444321038522 CDH11 other 1 1 1 2.92505084081039 0.999217490634097 4.62442413558901e-05 108.878790498768 33.4518302602511 3.25479322511517 0.00125654250512761 -140.419102703421 90.110293530842 -1.55830257788873 0.12015304756563 NOL3 other 0.414440891031488 1 1 3.25479322511517 -1.55830257788873 6.68207524233449e-15 165.551042541544 41.3611048230781 4.00257786269703 7.79162992702672e-05 -516.88232750717 105.611856932018 -4.89416948553311 1.56783455157179e-06 MAP1LC3B other 9.17582572277373e-11 0.0234297195386889 0.81664073265167 4.00257786269703 -4.89416948553311 4.08837604286432e-05 252.624748022553 83.3159819355417 3.03212831624548 0.00262682128211057 -359.617815445066 216.288550199612 -1.66267615698185 0.097356398061653 MBTPS1 essential 0.368485332743361 1 1 3.03212831624548 -1.66267615698185 2.8244478892597e-05 514.843126267258 138.950034874573 3.70523927346973 0.00024875067625873 -297.86090181498 359.54972057756 -0.828427571398229 0.408045840478241 CDH13 other 0.258832404571759 1 1 3.70523927346973 -0.828427571398229 5.83458012774561e-07 166.499114086525 43.9078690938715 3.79201080632184 0.000178605649333301 -203.942180585813 112.114790181918 -1.81904796195841 0.0698386108400422 ZCCHC14 other 0.00613856175240115 1 1 3.79201080632184 -1.81904796195841 2.81033609873587e-18 257.78402509965 66.3611094374957 3.88456472902178 0.000124588826801843 -1031.200716966 170.577952835233 -6.04533411162503 4.15005962593684e-09 TLDC1 other 4.0187806211923e-14 6.32012580433922e-05 1 3.88456472902178 -6.04533411162503 0.180099359230838 3.58725426496772 7.53705343482043 0.475949161829604 0.634435363892887 -26.782963031234 19.3736234402827 -1.38244469929902 0.167799265942841 ADAD2 other 1 1 1 0.475949161829604 -1.38244469929902 0.464406583867836 58.2496469757591 76.3650508091806 0.762778867538661 0.446157201078947 -103.819122146387 198.243911212807 -0.523693875444889 0.600853965323924 OSGIN1 other 1 1 1 0.762778867538661 -0.523693875444889 0.000391343975499324 -66.7444707022812 23.5822025190423 -2.83028994634347 0.00494459296756325 75.7309654264221 60.2150307453422 1.25767544231106 0.209426174413311 IRF8 other 1 1 1 -2.83028994634347 1.25767544231106 1.2392116824659e-06 236.645568895784 65.0877715207844 3.63579153758885 0.000323127300551933 -458.589982250713 175.705895661584 -2.60998630992995 0.0094830028330842 RHOT2 other 0.0127514882125741 1 1 3.63579153758885 -2.60998630992995 0.0884252313216841 120.951596644907 55.2682124836218 2.1884477751248 0.029361846521188 49.1842902043929 157.009542599134 0.313256693766486 0.754290364239073 RPL3L other 1 1 1 2.1884477751248 0.313256693766486 0.000191602160220433 25.8060539623735 10.0670608183391 2.56341492596953 0.0108214819361507 -72.4966558301078 28.9310763713407 -2.50584025632463 0.0127121855478036 ZSCAN32 other 1 1 1 2.56341492596953 -2.50584025632463 0.000681373713976346 1892.28003050084 601.162507618274 3.14770133952266 0.00180102374589492 -2158.58809276721 1707.82165927412 -1.26394233323208 0.207173538788348 RPS2 essential 1 1 1 3.14770133952266 -1.26394233323208 0.00374252523721785 252.783516152429 82.536950168217 3.06267090845053 0.00238049242994656 -115.899523517268 234.476351072138 -0.494290886852 0.621440965459335 NDUFB10 essential 1 1 1 3.06267090845053 -0.494290886852 2.16661472399273e-06 74.3652457612298 38.0926737877591 1.95221911109655 0.0517839960290538 -447.592500460064 109.089365307984 -4.10298931702839 5.1797980621348e-05 PDPK1 other 0.0218286433442268 0.74697867854046 1 1.95221911109655 -4.10298931702839 0.242708343890079 9.98005473133865 9.75103071711885 1.02348715954896 0.306850657561106 43.900361775127 28.0228578595989 1.56659117335848 0.118198594922178 TIGD7 other 1 1 1 1.02348715954896 1.56659117335848 3.20032036921913e-17 104.117573772004 21.8211998600676 4.77139545211431 2.7893224693297e-06 -278.537078179763 55.7196561906391 -4.99890159456075 9.5285782473173e-07 DEF8 other 4.52237271374355e-13 0.0142833387927286 0.0324314523508965 4.77139545211431 -4.99890159456075 3.65522891199835e-08 80.8439655769096 59.2363581453422 1.36476934281731 0.173287412328579 -702.405630404825 151.257929491042 -4.64376071236931 5.0075560451115e-06 TCF25 other 0.000412785001031973 0.0742420259248232 1 1.36476934281731 -4.64376071236931 5.65651074599011e-10 197.038122707956 39.919308157493 4.93591026003217 1.2861198982914e-06 -187.486951051043 101.568068787465 -1.84592415007285 0.0658267118479346 GALNS other 6.90716527192852e-06 1 0.015253381993736 4.93591026003217 -1.84592415007285 0.000783583926248954 0.0580679219650429 12.0237776541643 0.00482942413235094 0.996149720207684 -105.205209799278 30.6984551450122 -3.42705225075052 0.000690392144004175 GAS8 other 1 1 1 0.00482942413235094 -3.42705225075052 6.64372828787295e-11 69.3501436446929 12.1687697902111 5.69902667568581 2.74239779658856e-08 -89.2851474715204 23.0619208961306 -3.87153992391418 0.000131198762692273 MED9 other 8.36378954160326e-07 1 0.000349162087461656 5.69902667568581 -3.87153992391418 5.27634526417286e-16 520.632618285642 70.8611433389583 7.3472229455181 1.71730835848372e-12 -646.232214346306 148.236299107885 -4.35947347738345 1.76270407278559e-05 NCOR1 other 7.35839110541547e-12 0.257865978807805 2.40423170187721e-08 7.3472229455181 -4.35947347738345 3.51810809471743e-18 383.603783783783 43.6918346362216 8.77975912381958 1.01670582194907e-16 -276.88223938224 93.0232613426603 -2.97648389645593 0.00313874724873929 COPS3 essential 5.02456198087544e-14 1 1.48256042956613e-12 8.77975912381958 -2.97648389645593 2.12428133488863e-13 117.683262704366 14.8606092917994 7.91914115993268 4.00748210798695e-14 -19.9939716485732 27.8135569067995 -0.71885705649123 0.472755223542798 GID4 other 2.83803986341121e-09 1 5.72789417694575e-10 7.91914115993268 -0.71885705649123 6.35445520722321e-06 17.2435805937287 3.63957767570134 4.7377971100468 3.25381370786895e-06 15.3641137997983 7.7844016430594 1.97370517405111 0.049275211496674 ZNF287 other 0.0617081145173446 1 0.037692177991954 4.7377971100468 1.97370517405111 0.0962514321481034 34.3370981009944 47.3266251594293 0.725534474206072 0.468676898838877 -220.715593824342 114.955973089651 -1.92000109165455 0.0557841825787543 KSR1 other 1 1 1 0.725534474206072 -1.92000109165455 2.0852352333821e-15 299.18201522768 45.630725557833 6.55659123474801 2.21603889207377e-10 -327.744245135081 124.461284682895 -2.63330276535481 0.00886776821220071 UTP4 other 2.88575703947749e-11 1 2.99032288096434e-06 6.55659123474801 -2.63330276535481 1.76135689761772e-12 105.621019427116 21.1222801833711 5.00045537272383 9.45765354130106e-07 -185.512700851081 56.5425852440995 -3.28093772243002 0.00114914141929477 RANBP10 other 2.30702526449969e-08 1 0.0112896010322511 5.00045537272383 -3.28093772243002 1.08574865147558e-08 14.4946799868046 3.39822954108696 4.2653622457088 2.63312184599384e-05 -21.9209843050173 9.09677751823384 -2.40975271309848 0.0165291736030802 CTRL other 0.000125718836354358 1 0.286957618776409 4.2653622457088 -2.40975271309848 1.23643522943166e-11 153.98902680604 30.0886981932214 5.11783613292819 5.35023081940209e-07 -222.27238965397 80.5449396421498 -2.75960712915666 0.00612148695219765 GFOD2 other 1.58634639936081e-07 1 0.0064587986451822 5.11783613292819 -2.75960712915666 5.5814764047842e-15 257.291494283369 44.2414685054301 5.8156183095909 1.46358534100517e-08 -415.103069320883 120.678964837361 -3.4397301127029 0.000659457656955027 NOB1 essential 7.67173931837589e-11 1 0.000188158531439625 5.8156183095909 -3.4397301127029 1.13698101034694e-09 163.445067510908 26.7224167989912 6.11640289650291 2.78935258745913e-09 -110.953903794154 49.915870131096 -2.22281818393131 0.0269264853771055 PRPSAP2 other 1.37040321177116e-05 1 3.66911439354374e-05 6.11640289650291 -2.22281818393131 0.0300542370803593 48.3848582790925 46.7336867472026 1.03533150596104 0.301303268940883 291.364054275458 114.161638205072 2.55220631778314 0.0111729968730525 UNC45B other 1 1 1 1.03533150596104 2.55220631778314 0.572757586192638 17.1444834990822 16.2639840665156 1.05413799158715 0.292625068413347 1.43265274295517 38.5240402920968 0.037188538172334 0.970358159194129 PCTP other 1 1 1 1.05413799158715 0.037188538172334 0.0423187752774631 43.8807321027586 29.8950227439741 1.46782735301994 0.143145746068364 -136.340570522433 70.9892803329552 -1.92057969714535 0.0556844292927073 TOM1L1 other 1 1 1 1.46782735301994 -1.92057969714535 7.83439686387721e-09 89.7333779479327 14.6273068231081 6.1346479589922 2.52541010908025e-09 -20.4340838186289 34.5895403795439 -0.590759044335656 0.555100188315007 C17orf80 other 9.13804050202638e-05 1 3.32546003163687e-05 6.1346479589922 -0.590759044335656 0.0105007105399868 72.2203921097942 65.6470007996409 1.10013239340843 0.272103935633667 -431.668355853256 156.526255944155 -2.75780157935463 0.00615459295463393 TOB1 other 1 1 1 1.10013239340843 -2.75780157935463 1.23943867629242e-15 245.364323028561 29.385880368164 8.34973531350733 2.19435586756708e-15 -125.39954901501 55.9252456321536 -2.24227086707534 0.0256393892023568 VPS53 other 1.71996905109098e-11 1 3.17216084215497e-11 8.34973531350733 -2.24227086707534 0.00129826769463368 10.2188291790466 2.77396812557105 3.68383078552604 0.000269809954512756 1.17701362559502 5.261520888693 0.223702167205003 0.823132252800341 SPATA22 other 1 1 1 3.68383078552604 0.223702167205003 5.67009569601028e-11 214.551152681873 34.4138859018706 6.23443552098864 1.43573835319483e-09 -204.466353149544 65.4696573512341 -3.12307046381219 0.00195382100341612 SGSM2 other 7.15395973965616e-07 1 1.9019225964772e-05 6.23443552098864 -3.12307046381219 0.00696095140658955 267.864717125576 95.5994359906903 2.80194871810396 0.00538990209107446 -285.982215380936 227.345777274019 -1.25791742784931 0.209341623660764 NPEPPS other 1 1 1 2.80194871810396 -1.25791742784931 0.00547014600352862 -39.8077735673212 13.0917660195214 -3.0406725500565 0.00255609844223287 -43.8500088289835 31.1336326491249 -1.40844498691084 0.159973221937598 SKAP1 other 1 1 1 -3.0406725500565 -1.40844498691084 0.39811230867869 -14.0870865158235 12.5191723542035 -1.12524103968371 0.261332808413446 -25.3691925366412 29.7813573971941 -0.851848094037225 0.394937451048903 LRRC46 other 1 1 1 -1.12524103968371 -0.851848094037225 0.270071498569872 47.1574005966763 29.4302910078467 1.60234231404994 0.110069633146933 -8.11568848599426 70.010539835233 -0.115920952832162 0.907788128376281 SCRN2 other 1 1 1 1.60234231404994 -0.115920952832162 0.000320792011302124 108.03831378989 32.7241832066064 3.30148236574104 0.00107186377398749 -145.440702302756 79.0002954983701 -1.84101466184714 0.0665567011747131 SSH2 other 1 1 1 3.30148236574104 -1.84101466184714 0.569282990682257 -2.32815399272795 15.6476353347471 -0.148786314540323 0.881817153517294 -41.2233657791539 38.8017069784529 -1.06241114088217 0.288860317785281 RHBDL3 other 1 1 1 -0.148786314540323 -1.06241114088217 0.000362048107442479 70.1311512665744 17.4105032910965 4.02809442633623 7.03874703351619e-05 14.3410863619025 40.7377389581295 0.352034421366448 0.725045620470844 ARSG other 1 1 0.741180062629255 4.02809442633623 0.352034421366448 0.635162465259918 -0.446370361589886 14.2720922393353 -0.031275748089663 0.975069251270123 31.5054095701978 33.4783233579482 0.941068918934317 0.347383859426415 ABCA8 other 1 1 1 -0.031275748089663 0.941068918934317 0.0650505071434665 72.5755801614632 36.3485455290107 1.99665706303265 0.0467119061344431 -94.1717031746525 87.6017543187146 -1.07499791422024 0.283188069930377 G6PC3 other 1 1 1 1.99665706303265 -1.07499791422024 1.78085988743513e-08 1866.16124436384 327.978168749996 5.68989470084617 2.91424201658354e-08 -1140.10457062042 757.372504064231 -1.50534190837713 0.1332414352914 CLTC other 0.000204460523676427 1 0.000370575014828763 5.68989470084617 -1.50534190837713 0.079791386665718 66.4571402210762 29.7307787906006 2.23529765867037 0.0261074157927844 38.218645841496 68.3021932826063 0.559552248686407 0.57618763746646 BCAS3 other 1 1 1 2.23529765867037 0.559552248686407 2.0047755457916e-11 140.572673179088 20.5828261596427 6.82960989364585 4.45989110967475e-11 -75.9088324888696 47.6689550100488 -1.59241654181149 0.112303733223147 PTRH2 other 2.56049932708503e-07 1 6.09622515781442e-07 6.82960989364585 -1.59241654181149 7.86808374633238e-21 383.524560469671 59.2330996980212 6.47483522599583 3.97435121733779e-10 -452.070977939363 119.666475606866 -3.77775793635411 0.000191540907965011 SS18 other 1.1485828652896e-16 1 5.33795112000639e-06 6.47483522599583 -3.77775793635411 2.36035150276316e-12 108.659395354553 18.2136040213488 5.96583714168757 6.91330789123828e-09 -34.7636791376258 36.2494567359184 -0.959012417506924 0.33833252724454 TAF4B other 3.08285509775897e-08 1 8.9824609430859e-05 5.96583714168757 -0.959012417506924 8.46997673613711e-50 825.458323392099 46.0054632739495 17.9426151732617 6.50599106081333e-50 56.9885766191362 196.53922071012 0.289960326560926 0.77203981907431 AFG3L2 essential 1.29793923504565e-45 1 9.97303369712075e-46 17.9426151732617 0.289960326560926 5.50483212248458e-25 30.1492842310812 2.61010994447591 11.5509633204876 6.76284808334263e-26 12.4656224645554 10.9470990297471 1.13871468876658 0.255704220380854 PRELID3A other 8.20715421141225e-21 1 1.02064903273807e-21 11.5509633204876 1.13871468876658 3.5792048006168e-25 1188.31872006819 102.205587144561 11.6267491168308 3.34066397168432e-26 708.6831434268 436.960214326155 1.62184821453293 0.105845908515142 IMPA2 other 5.3398156420402e-21 1 5.04507073003767e-22 11.6267491168308 1.62184821453293 0.0270780211691286 63.1404671037301 23.7433592210777 2.65928955190462 0.00823478154869384 4.04749509995078 101.510138769524 0.0398728161444102 0.968220025314299 GNAL other 1 1 1 2.65928955190462 0.0398728161444102 1.83037693462495e-08 723.239197265459 170.343279556452 4.24577476228393 2.87494567282174e-05 -408.33642904234 304.880711487945 -1.33933178996299 0.181434410546905 SLC39A6 other 0.000210072360786906 1 0.312506594635723 4.24577476228393 -1.33933178996299 5.93564007040359e-17 302.24818803128 56.3136722260712 5.36722568576073 1.55655203356588e-07 -325.45462781676 100.535622964512 -3.23720705377876 0.00133602695383658 RPRD1A other 8.35975547515642e-13 1 0.00192374265828407 5.36722568576073 -3.23720705377876 1.62834861399458e-18 63.5494050297338 13.0712710297481 4.86176171277495 1.84186308802505e-06 -99.7647997713757 23.3358671876012 -4.27517001915329 2.53671847351498e-05 C18orf21 other 2.33260938954723e-14 0.369346209743781 0.021621630790326 4.86176171277495 -4.27517001915329 1.82034481022214e-11 878.702692987297 164.807478496485 5.33169186861894 1.86334527916147e-07 -356.362016171088 294.777851119125 -1.20891720601856 0.227604179881707 GALNT1 other 2.3264006674639e-07 1 0.00229489604581526 5.33169186861894 -1.20891720601856 0.459700794603822 -1.06206244592919 2.04643475902509 -0.518981824974061 0.604163845852345 -11.1073553305997 9.25019830431404 -1.20076942841534 0.230807194014917 ADCYAP1 other 1 1 1 -0.518981824974061 -1.20076942841534 5.58797018494216e-10 212.295311516679 40.4826499953426 5.24410609337834 2.870743588102e-07 -38.5929436752671 71.6213527106489 -0.538846897114371 0.590369515770162 GAREM1 other 6.82570558090685e-06 1 0.00350890988773708 5.24410609337834 -0.538846897114371 2.46724045710233e-08 156.769650200885 26.5880206973804 5.89625124732697 1.22094082867648e-08 48.2161987832789 62.0027709965955 0.777645869826147 0.43752503367719 ESCO1 other 0.000281117377682239 1 0.000157318225774964 5.89625124732697 0.777645869826147 1.8557850424248e-17 326.546628397679 37.5224796444896 8.70269319862592 2.75855345134265e-16 63.8124849162471 81.0535884220453 0.787287597730726 0.431774706501445 OSBPL1A other 2.63168876866261e-13 1 4.01148842894248e-12 8.70269319862592 0.787287597730726 0.747264415999329 9.18557028319115 12.5320905066387 0.732963927951624 0.464251040885527 14.5857043258856 29.3814072629975 0.496426335039937 0.620019629296204 GATA6 other 1 1 1 0.732963927951624 0.496426335039937 0.0927510955551317 12.1925127084042 5.60403413256855 2.17566710337217 0.0305324999021787 8.13396490857891 13.0685036292674 0.622409813650172 0.534248917472852 GREB1L other 1 1 1 2.17566710337217 0.622409813650172 2.05492792216877e-19 182.047878384972 22.0718290696752 8.24797427572915 6.64111497931809e-15 -67.4911638945016 48.7593159464454 -1.38416962142435 0.167424703483114 C18orf8 other 2.96649394844283e-15 1 9.55722856673666e-11 8.24797427572915 -1.38416962142435 4.08057605231993e-18 738.281275622499 78.7061872176843 9.38021903640907 1.25224574712871e-18 -197.300384812826 148.174946563891 -1.33153673673 0.183960188743834 PELP1 essential 5.823798141871e-14 1 1.84706247701485e-14 9.38021903640907 -1.33153673673 8.3880915362705e-15 610.277541986014 85.1879099554866 7.16389851922537 7.100331038335e-12 -171.763935245622 187.14779681537 -0.917798329280228 0.359522887499126 NPC1 other 1.15017511145341e-10 1 9.84531901775531e-08 7.16389851922537 -0.917798329280228 0.397571940293104 -12.9580250081721 15.3421457535628 -0.844603174569823 0.398973443318639 -33.571261681529 24.7032300939536 -1.35898267367659 0.175124295486383 SLC14A1 other 1 1 1 -0.844603174569823 -1.35898267367659 1.08239009685378e-05 105.964135133943 29.3040064417693 3.61602893257981 0.000347428223229849 -171.192621687769 55.168719793372 -3.10307403051858 0.00208601996574557 ARRB2 other 0.102935298210794 1 1 3.61602893257981 -3.10307403051858 0.0219529132864933 125.842490510845 45.8176072293685 2.74659673694574 0.0063626061795463 48.4034594262265 87.4565547708514 0.553457194295505 0.580336862521348 SLC13A5 other 1 1 1 2.74659673694574 0.553457194295505 3.24136614859125e-05 3.88981932012737 4.51621356126934 0.861301014080939 0.389717190535139 -38.2562376563216 8.50237734501573 -4.49947539422585 9.5461487520978e-06 ZMYND15 other 0.294964319521804 0.140586132672144 1 0.861301014080939 -4.49947539422585 7.87123742510141e-13 115.045226245133 16.896079639861 6.80898934529875 4.91246475964803e-11 -114.503325598794 32.359051162087 -3.53852543528687 0.000462348419411354 WRAP53 other 1.03931818961039e-08 1 6.70797062929939e-07 6.80898934529875 -3.53852543528687 2.26344028510975e-07 534.704345255291 131.804134181569 4.05681011885941 6.25605473353612e-05 -1141.49163195552 295.251519867774 -3.86616682774985 0.000133910357956473 MINK1 other 0.00244881604446024 1 0.661890590808121 4.05681011885941 -3.86616682774985 7.65015397302278e-09 189.973538476065 31.279159544792 6.07348602842163 3.54717709612152e-09 117.549832014137 59.9630216441498 1.96037205582693 0.0508196682164864 SAT2 other 8.92925971731219e-05 1 4.6499944553057e-05 6.07348602842163 1.96037205582693 6.77052321005143e-07 20.7874824286133 3.85374527050205 5.39409871942709 1.34149813051811e-07 7.53365885638522 7.35602107363076 1.02414862341698 0.306538657746097 ASGR1 other 0.00708738369628184 1 0.001662250333525 5.39409871942709 1.02414862341698 0.111539073447279 -14.4602160511899 9.80861608582643 -1.47423611288906 0.141404187818927 -28.8336086035286 18.2761753510228 -1.57766097390365 0.115634617431979 PIK3R5 other 1 1 1 -1.47423611288906 -1.57766097390365 3.93994428034932e-06 148.167254624007 108.342892298521 1.36757706463805 0.172413287883764 -1004.26873880577 207.531629789088 -4.83911170469001 2.03993653463917e-06 TP53 ts 0.0389384693226923 0.0304378930333511 1 1.36757706463805 -4.83911170469001 0.284040077720348 5.36732784859373 5.34079986829376 1.00496704256931 0.315672028909947 -11.9237590681282 12.3125423260488 -0.968423803336043 0.333564117587541 CCDC40 other 1 1 1 1.00496704256931 -0.968423803336043 7.71288942039597e-12 1313.86299866838 245.618133411259 5.34921009463283 1.688857861175e-07 -2121.32004541436 550.053609281594 -3.85656963179452 0.000139111559925167 ARHGDIA other 9.95039864125284e-08 1 0.00208303728597325 5.34921009463283 -3.85656963179452 0.0908688601374652 -64.0825308061419 71.3286312609653 -0.898412456166268 0.369641183123557 -360.600081258149 168.129091915056 -2.1447809962617 0.0327230055406332 TMC6 other 1 1 1 -0.898412456166268 -2.1447809962617 0.0362874123370356 35.5818259119619 23.5723783360663 1.50947118719543 0.132165137708204 -92.4306531340821 54.3431533002145 -1.70087025726049 0.0899388265971773 CARD14 other 1 1 1 1.50947118719543 -1.70087025726049 0.000160827525067669 54.0041177501313 13.8523608806453 3.89854972848612 0.000118060163110591 71.2121298405465 32.79895654447 2.17117059025931 0.0306574756567485 TTYH2 other 1 1 1 3.89854972848612 2.17117059025931 0.00705696940741355 74.4791345682828 23.6824819336047 3.14490410156712 0.00182087886700908 15.5253445123346 52.6257070687004 0.295014459227445 0.768178419725481 RAB40B other 1 1 1 3.14490410156712 0.295014459227445 8.69970709937251e-09 497.949464136555 97.9444587133438 5.08399832596874 6.30182768194194e-07 -544.56415200128 225.798630027163 -2.41172478298814 0.0164399061309653 EIF4A3 essential 0.000101308089172193 1 0.00758361943244893 5.08399832596874 -2.41172478298814 8.978651926939e-15 551.605591467513 72.6068651216045 7.59715476688967 3.43585885412662e-13 -316.38466541962 162.627386426138 -1.9454574802708 0.0526036793797375 CSNK1D other 1.23061403310626e-10 1 4.85074553025596e-09 7.59715476688967 -1.9454574802708 0.0493836824569783 231.904143378135 95.7751586221742 2.4213391730624 0.0160227197585029 21.0477952951134 214.477665982471 0.0981351377482519 0.92188681300381 ANAPC11 essential 1 1 1 2.4213391730624 0.0981351377482519 0.715126534203673 61.5606270923485 92.2868967370463 0.667057071685417 0.505230287186024 -61.3840099368801 203.273355099123 -0.301977649293717 0.762870940438707 TBCD essential 1 1 1 0.667057071685417 -0.301977649293717 0.000866424055798098 79.3707036750798 33.1123812901168 2.39700983688449 0.0171174716922969 -171.723386769209 73.3518186758217 -2.34109242100922 0.0198567497528294 FN3KRP other 1 1 1 2.39700983688449 -2.34109242100922 0.00232418710484833 153.420983791994 43.8040865277911 3.50243541078427 0.000527247033029101 47.4460939523984 98.1139193224769 0.483581680153399 0.629016638457205 NARF other 1 1 1 3.50243541078427 0.483581680153399 4.3742468863618e-13 231.654498821156 34.4146783560289 6.73127019885613 7.85570721729696e-11 -192.854737579444 79.3261975955615 -2.43116074418062 0.0156027537407294 RPTOR essential 5.80550046757938e-09 1 1.06924030934629e-06 6.73127019885613 -2.43116074418062 2.8736848211282e-13 419.046825445337 61.143368035155 6.85351230904392 3.82010093660113e-11 -327.754282760867 136.285861964974 -2.40490303275258 0.0167552050414164 FOXK2 other 3.82861028718909e-09 1 5.23048220239427e-07 6.85351230904392 -2.40490303275258 4.67804889910009e-05 107.337989566616 23.6659620258758 4.53554304909537 8.15148620818204e-06 36.9003539067417 58.2640016774952 0.633330235554258 0.526973224387538 TRIM65 other 0.418966059403404 1 0.0920954911800407 4.53554304909537 0.633330235554258 0.00339991460712013 32.6952967805918 10.1973341417662 3.20625923658602 0.00148054660536902 42.2211742362326 23.5556686123177 1.79239973745234 0.0740134592900017 CBX8 other 1 1 1 3.20625923658602 1.79239973745234 0.00886959561585667 -198.788959201456 67.964424553667 -2.92489726069094 0.00369416261647185 -251.100879837782 152.229086280031 -1.6494934442152 0.100037111660515 SECTM1 other 1 1 1 -2.92489726069094 -1.6494934442152 0.993605848908656 -0.384554186027775 14.9909523554812 -0.0256524186661943 0.979550665628877 -4.14924101291984 36.680390010666 -0.113118781226517 0.910007762261512 RNF157 other 1 1 1 -0.0256524186661943 -0.113118781226517 0.000138551373680629 100.403725600842 23.8490065857984 4.20997517190631 3.33074692455401e-05 13.233149877798 54.7258873197387 0.241807863260082 0.80908539425834 CEP131 other 1 1 0.360619969521462 4.20997517190631 0.241807863260082 0.321297546697067 182.877976919517 144.983861645043 1.26136781600733 0.208121663861699 -160.601228253797 319.344966986894 -0.502908280562906 0.615384712547876 ZNF750 other 1 1 1 1.26136781600733 -0.502908280562906 3.97484586529689e-07 434.4060020937 87.0986649766938 4.9875161945357 1.01404290021077e-06 -246.108763672686 194.139070414346 -1.2676931188937 0.205846808350225 WDR45B other 0.00423122342360854 1 0.0120894194563128 4.9875161945357 -1.2676931188937 0.0135813389854639 85.8992242731002 30.0923495736298 2.85452035119167 0.00459140159300433 -7.14857385258873 69.4413721498039 -0.102944017827979 0.918071883806026 CBX4 other 1 1 1 2.85452035119167 -0.102944017827979 0.000147706088168429 5.87041630554975 38.075448829923 0.154178518860591 0.877567711248734 -205.870136662297 61.4662294852292 -3.34932105623576 0.000908473512964192 RNF165 other 1 1 1 0.154178518860591 -3.34932105623576 5.36963177706304e-31 293.079388330131 37.6911985161424 7.77580442830998 1.06761010561811e-13 -217.160534684662 59.3320029936749 -3.6600910761063 0.000295387520280898 DYM other 8.1264007314072e-27 1 1.51867537524176e-09 7.77580442830998 -3.6600910761063 0.00977145718300368 -2.10198665218074 9.2936550862215 -0.226174377322985 0.821211102032924 -35.7365470630565 14.3287317470865 -2.49404816098416 0.0131370552394676 MAPK4 other 1 1 1 -0.226174377322985 -2.49404816098416 2.40095978850982e-17 5.68015453436363 7.03421628324128 0.807503537799421 0.419981927506661 -73.4341195607969 11.0048980300882 -6.67285779114196 1.11995467441653e-10 ELAC1 other 3.39903877259335e-13 1.71297067452008e-06 1 0.807503537799421 -6.67285779114196 1.83051940618435e-14 55.6232184939961 87.9298648202933 0.632586193640535 0.527458490941469 -826.343115250814 135.223777335547 -6.11093057399446 2.89434204078647e-09 MBD1 other 2.4933504831637e-10 4.40953009913819e-05 1 0.632586193640535 -6.11093057399446 9.43337409275118e-24 405.093779667216 67.3782663595213 6.01223215666741 5.03209134838241e-09 -373.496363897326 105.412020454535 -3.54320467710242 0.000454724746292234 SMAD4 ts 1.39878071047314e-19 1 6.56486637309969e-05 6.01223215666741 -3.54320467710242 3.09588104081331e-06 14.5707335208543 16.0718146746024 0.906601638698573 0.36530178547433 -89.9606842657839 26.1308165786934 -3.44270466997714 0.000652754970387744 TNFRSF11A other 0.0308566463337862 1 1 0.906601638698573 -3.44270466997714 2.49636952655641e-13 97.1530085029994 24.2091545540404 4.01306903494427 7.47408991346628e-05 -117.76889524392 39.3611418489379 -2.99200911639959 0.00298762118122184 ZCCHC2 other 3.33090585928421e-09 1 0.785201827564072 4.01306903494427 -2.99200911639959 0.0296108955897435 12.7532613868094 32.786713208695 0.388976513309886 0.697555493260551 -89.9301115066325 49.7341799852729 -1.80821542716221 0.0715235400466848 CBLN2 other 1 1 1 0.388976513309886 -1.80821542716221 1.97457340335904e-06 73.6582866154237 67.0499900296695 1.09855775642666 0.272786867942259 -341.478071783032 101.727433869511 -3.35679431588784 0.000883541292347642 PMAIP1 other 0.0199609625345566 1 1 1.09855775642666 -3.35679431588784 1.0266849461961e-08 327.957275078523 55.345647976001 5.92561993710385 8.04076934105721e-09 352.413792660191 142.796596387473 2.46794252507203 0.0141118572351205 P3H4 other 0.000119074920059824 1 0.00010420032989076 5.92561993710385 2.46794252507203 1.80257839658454e-05 162.317535862065 34.1816460130036 4.74867523349564 3.09455889526121e-06 14.2051820917512 88.1916264074613 0.161071778244804 0.872138508022978 NT5C3B other 0.168144512833406 1 0.035884504949449 4.74867523349564 0.161071778244804 1.80114402215484e-08 263.085358025798 46.1135686970433 5.70516152749345 2.64784648404464e-08 -210.634545667911 118.948217483177 -1.77080876136459 0.077544427882683 RETREG3 other 0.000206771333743376 1 0.000337388598996968 5.70516152749345 -1.77080876136459 0.746463736238039 -506.620298882078 1474.52186291038 -0.343582765115549 0.731390029847867 -2589.9686312446 3693.05897855212 -0.701307140310013 0.483630774952112 ERBB2 og 1 1 1 -0.343582765115549 -0.701307140310013 0.0109586975357781 127.951697674051 67.179731114701 1.90461759151118 0.0577434107103884 -377.648862197827 168.257057023334 -2.24447561890646 0.0254979562398145 GRB7 other 1 1 1 1.90461759151118 -2.24447561890646 0.936844568432651 -11.4984708104157 182.906508790036 -0.0628652905054084 0.949913772665425 -164.292929489464 458.104109212331 -0.35863666399315 0.720107922890394 MIEN1 other 1 1 1 -0.0628652905054084 -0.35863666399315 0.0897036928810144 -17.9693842101287 42.5015678864156 -0.42279344277725 0.672733532382863 221.126308349189 104.109822328312 2.12397162346376 0.0344489236877009 STAC2 other 1 1 1 -0.42279344277725 2.12397162346376 0.00623227810983106 1298.79957671742 420.927946790206 3.085562711199 0.00221016503823568 1371.67159033407 1217.48243044429 1.12664590143901 0.260741683717909 IGFBP4 other 1 1 1 3.085562711199 1.12664590143901 2.4985383368117e-06 964.558553654518 199.660851411651 4.83098487677907 2.1106154600971e-06 1177.19134960887 515.142401544771 2.28517657657144 0.0229563532217849 FKBP10 other 0.0250728322099055 1 0.0247047539604365 4.83098487677907 2.28517657657144 2.54617502794889e-12 130.745286763446 65.9906942990266 1.9812685432736 0.0484444627462773 -431.592498312564 97.5026183021286 -4.42647085614871 1.32867640645451e-05 TXNL4A essential 3.32301302897609e-08 0.195036409703458 1 1.9812685432736 -4.42647085614871 0.169360243659041 9.17967782612154 5.09498880373643 1.80170716359368 0.0725505918216173 -0.787361642829298 11.3895161345946 -0.0691303856568378 0.944929837190747 CACNA1A other 1 1 1 1.80170716359368 -0.0691303856568378 6.55330100391954e-05 168.035364493546 49.1164616266368 3.42116184530723 0.000705777439976529 -230.56042616661 121.831868501468 -1.89244759193554 0.0593480976439076 SAMD1 other 0.576428356304763 1 1 3.42116184530723 -1.89244759193554 3.65842779939081e-16 757.259779966078 91.9155455715129 8.23864750252621 4.5554169099603e-15 -311.770911799008 246.72464406166 -1.26363911876226 0.207282258943992 BRD4 og 5.10972610740914e-12 1 6.56708901739877e-11 8.23864750252621 -1.26363911876226 2.0523556254032e-10 87.4601933399752 26.6941188544797 3.27638435330103 0.00116758669537643 -173.883451803994 46.352969132059 -3.75129047955056 0.000209026131101822 SLC39A3 other 2.54635762443775e-06 1 1 3.27638435330103 -3.75129047955056 1.38474542821122e-05 194.752272774756 157.363014151793 1.23759877010805 0.216780759849949 -983.305418863297 279.527757135385 -3.51773801979547 0.00049884149349807 NFIC other 0.130567646426036 1 1 1.23759877010805 -3.51773801979547 0.00113739714162411 32.7381680911817 14.1600031142486 2.31201701207529 0.0214152863959141 -30.5216682114872 23.0594370347238 -1.32360855841912 0.186583835704129 TPGS1 other 1 1 1 2.31201701207529 -1.32360855841912 3.15374865232858e-08 180.267187286863 120.143762203607 1.50042901920588 0.134498615735069 -836.044298185786 196.414181263508 -4.25653734780053 2.73792101888642e-05 PLPP2 other 0.000357351259795351 0.398340129037785 1 1.50042901920588 -4.25653734780053 0.000545869617267299 -4.62217082438483 22.292090468023 -0.20734577723947 0.835872123948256 -132.635908173454 36.1965562536098 -3.6643239551339 0.000290319367761477 PRDM15 other 1 1 1 -0.20734577723947 -3.6643239551339 1.31183264802054e-15 1114.31078603816 210.050679613739 5.30496158397229 2.11200829269423e-07 -1496.6325496404 345.970772806076 -4.32589301547532 2.03454235436547e-05 PFKL other 1.8199054325989e-11 0.297022838313815 0.00259586939255048 5.30496158397229 -4.32589301547532 0.0044933690709887 265.20403991658 106.28960806794 2.49510789189346 0.013095463066405 -171.764461804688 201.719597806374 -0.851501111803527 0.395127803095769 FEM1A other 1 1 1 2.49510789189346 -0.851501111803527 0.498452408086337 -6.13368582904483 21.3809630203683 -0.286876031879464 0.77439290359226 -44.194084975524 38.3053701625094 -1.15373078991358 0.249471524985785 VAV1 other 1 1 1 -0.286876031879464 -1.15373078991358 1.39155096713828e-07 129.142893466007 33.7656687373045 3.82468046081756 0.000157586882851626 -236.114855994195 78.7714942345672 -2.99746574936217 0.00293679508915909 MVB12A other 0.00152333084372627 1 1 3.82468046081756 -2.99746574936217 2.6481905267549e-13 400.829938225973 120.880315769832 3.31592398376252 0.00101838580466328 -1100.42006270441 223.99868234455 -4.91261846358439 1.43665358099829e-06 SH3GL1 other 3.53189170553301e-09 0.0214794076895055 1 3.31592398376252 -4.91261846358439 1.78123833973694e-10 155.744387400937 36.1644777579862 4.30655707081362 2.2118789861422e-05 -195.05120859744 66.2616771006777 -2.94365034409075 0.00348243201873545 DUS3L other 2.21229801795328e-06 1 0.242399818091323 4.30655707081362 -2.94365034409075 7.67803821680876e-15 294.490364239319 70.879945977599 4.15477692847552 4.18608326194966e-05 -625.695782065695 133.377615263591 -4.69116036322246 4.03544056303738e-06 DPP9 other 1.05311972181749e-10 0.0599424341233573 0.449669063998632 4.15477692847552 -4.69116036322246 1.19803972946725e-08 171.920572796565 35.1417216498587 4.89220689041728 1.58463856329228e-06 -215.275273149586 91.7612713742697 -2.34603629532916 0.0195861408627403 CCDC97 other 0.000138505373123709 1 0.0186908118540325 4.89220689041728 -2.34603629532916 0.027765653512001 47.112391725433 26.9363154809643 1.74902880680645 0.0812478006947188 -104.684433618153 70.3354997600592 -1.48835842462584 0.137644264341615 TMEM91 other 1 1 1 1.74902880680645 -1.48835842462584 0.18175895310493 4.16019618676167 7.48572531495654 0.555750580167505 0.578772155859398 -32.3128035200747 21.1063608122716 -1.53095096816915 0.126775668972333 ZFP14 other 1 1 1 0.555750580167505 -1.53095096816915 2.09321794801377e-11 69.9063790876422 14.340030355227 4.87491151384912 1.72416403151645e-06 -41.0952878921881 26.9107943555268 -1.52709308202744 0.127734993482992 SIRT3 other 2.67157406704997e-07 1 0.020284789830791 4.87491151384912 -1.52709308202744 2.08715211226493e-06 3775.31526247526 1084.44652401776 3.48132911938167 0.000568459987124008 -2191.92597644733 2034.25935889249 -1.07750566163829 0.28206856379414 IFITM3 other 0.0210405804437428 1 1 3.48132911938167 -1.07750566163829 0.0247066228035834 -84.5746455182299 78.6993008641708 -1.07465561433893 0.283341113370857 -393.378409833331 147.628108694655 -2.66465792532078 0.00809852894870802 PGGHG other 1 1 1 -1.07465561433893 -2.66465792532078 0.0922970411010341 32.0953281476726 16.3258357552321 1.96592251869169 0.0501911966852939 -6.44240318513763 26.8184538390332 -0.240222766897955 0.810314819269621 HUNK other 1 1 1 1.96592251869169 -0.240222766897955 0.324822614029541 2779.4086815141 1985.67075637868 1.39973289760432 0.162568093763079 3497.32689831042 3334.41365395093 1.04885813857152 0.295039893015494 COL6A1 other 1 1 1 1.39973289760432 1.04885813857152 1.20348707472075e-09 169.218255734378 55.4784113473475 3.05016404804585 0.00248204081329344 -424.899330315071 92.3242484421359 -4.60225062737853 6.07478463324569e-06 IFNAR1 other 1.44960018150114e-05 0.0899371864952024 1 3.05016404804585 -4.60225062737853 1.25868305919935e-07 548.277855905459 195.350409733854 2.80663785989717 0.00532097105774905 -1224.14940835698 322.378053468953 -3.79724796767183 0.000175818397565704 SOD1 essential 0.00138102705255353 1 1 2.80663785989717 -3.79724796767183 0.184202845472707 4444.49623317743 2635.84886414469 1.6861726382099 0.0927402845352268 5952.02293346119 4423.8862909982 1.345428553526 0.179442446664043 COL6A2 other 1 1 1 1.6861726382099 1.345428553526 0.0484957572974883 83.8574736718882 172.17092779052 0.48705942837177 0.626553893046034 -561.028267912174 276.859895329737 -2.02639774621021 0.0435636700392676 SIK1 other 1 1 1 0.48705942837177 -2.02639774621021 0.022790344638079 -2.8727660663 37.4558972046202 -0.0766972968396987 0.938912586520326 -160.00101740637 62.0785640793299 -2.57739559184882 0.0104049167536122 TRPM2 other 1 1 1 -0.0766972968396987 -2.57739559184882 4.45264674589495e-27 640.742561884261 53.3440438098504 12.0115108664848 1.24258798415384e-27 75.3916104579939 241.722089370888 0.311893756396902 0.755326954607594 SCYL1 other 6.68386803026291e-23 1 1.88127820800891e-23 12.0115108664848 0.311893756396902 2.69720380354105e-10 148.234212380775 46.7169249940733 3.17303016839359 0.00165835886770772 -373.862737046193 77.768122226727 -4.80740342368335 2.37828101893123e-06 TMEM50B other 3.33266501965532e-06 0.0354554134302268 1 3.17303016839359 -4.80740342368335 0.142273003910885 1401.45906267648 1396.85471180136 1.00329622747177 0.316661652969202 -2846.3343450028 2460.18811575125 -1.15695800934054 0.248363742013921 APP other 1 1 1 1.00329622747177 -1.15695800934054 0.000839413097165622 132.448587777287 46.8043598718077 2.82983440303532 0.00495524403765012 -113.762656594893 77.9810411147518 -1.45885018933624 0.145599599836888 DOPEY2 other 1 1 1 2.82983440303532 -1.45885018933624 2.61452955793898e-06 234.498064297439 79.0612470550453 2.96603042618558 0.00324886343080598 -386.728625874189 129.873927215189 -2.97772335191972 0.00313077791570968 URB1 essential 0.0261949716409907 1 1 2.96603042618558 -2.97772335191972 1.20585087292993e-13 687.884268575476 96.2694449252041 7.14540599158874 6.56151450572443e-12 -458.019037400854 284.287440650302 -1.6111124584088 0.108182820047285 AKT1 og 1.61776953112279e-09 1 9.10147677089036e-08 7.14540599158874 -1.6111124584088 0.532472591069096 -24.0282869909842 26.1281036824083 -0.919633789082142 0.358456863849499 -58.6583745177608 88.7318750045916 -0.661074439311977 0.509040238264112 IL19 other 1 1 1 -0.919633789082142 -0.661074439311977 0.235131220155626 71.9626367187499 83.5464648212614 0.86134867432998 0.389690987995691 -237.726145833334 191.415868579772 -1.24193541317742 0.21516984697205 EMP3 other 1 1 1 0.86134867432998 -1.24193541317742 6.03025238155908e-08 469.435199398719 111.923402443607 4.19425418768204 3.54879934289584e-05 -768.745820131419 253.473857746755 -3.03284065254363 0.00262080386314764 SAE1 essential 0.000672795258210547 1 0.383199353045893 4.19425418768204 -3.03284065254363 0.00201089292309075 59.2430468749999 17.9477397700269 3.30086393240096 0.00107272690312783 -22.9131547619048 41.1206171855775 -0.557218162813503 0.57776791536956 LMTK3 other 1 1 1 3.30086393240096 -0.557218162813503 1.53052656412926e-05 58.3545839282258 17.7637555877775 3.28503641247898 0.00113309835773693 -112.386248032747 43.0558503592705 -2.61024337215417 0.00947467640769781 GEMIN7 other 0.143701139106096 1 1 3.28503641247898 -2.61024337215417 3.7637416557809e-06 254.233871206541 54.3269978066536 4.67969667882888 4.25236360302149e-06 -292.364817459753 225.08683643391 -1.29889789243893 0.194917050961232 CBLC other 0.0372572786505751 1 0.0488936767075411 4.67969667882888 -1.29889789243893 0.000388564356250204 50.0707444534328 13.1795939818218 3.79911130210034 0.000173781437887938 -11.0111754876468 40.2776837997938 -0.273381546525352 0.784736293346953 WTIP other 1 1 1 3.79911130210034 -0.273381546525352 0.0594748796568881 16.0438730544187 7.77396422159789 2.06379558705005 0.0398455531351802 -4.1706563949046 15.254050259626 -0.273413049250491 0.784712654171972 ADAMTS10 other 1 1 1 2.06379558705005 -0.273413049250491 3.04325585035707e-06 21.3194665004924 14.0017819319354 1.5226252347115 0.128840056243684 -93.4081933531036 25.3581628287705 -3.68355523165605 0.000269957947260425 CAPN10 other 0.0303534338514614 1 1 1.5226252347115 -3.68355523165605 0.658515197564764 -18.2880323853586 32.4784846301109 -0.563081455112092 0.573774961515866 -56.4502459032326 63.7291892246926 -0.885783211586196 0.376401584199412 MYO1F other 1 1 1 -0.563081455112092 -0.885783211586196 1.70563669537243e-06 91.9621817615593 29.1456260138152 3.15526527781454 0.00175835533763226 -225.864092582498 74.4382718272774 -3.03424686035943 0.00261216601021334 ERVK3-1 other 0.01733438573507 1 1 3.15526527781454 -3.03424686035943 2.98980754735558e-09 137.88396657398 25.4533310116119 5.41712856800851 1.19490206706538e-07 -129.588614416362 69.3532925302794 -1.8685286550712 0.0626048404717465 ZNF787 other 3.55069544323948e-05 1 0.00148299295543484 5.41712856800851 -1.8685286550712 8.1704174933339e-10 47.8338565743177 12.0785417576599 3.96023440031432 9.25064220018487e-05 -100.545873995884 25.9260620403156 -3.87817763606109 0.000127980623735894 TIMM29 other 9.91806979515802e-06 1 0.962344308085232 3.96023440031432 -3.87817763606109 0.0702394907239039 58.921269428618 26.4270056512205 2.2295855310379 0.0264685992685427 18.2982396650524 49.233852827085 0.37165971408571 0.710392193589244 FBN3 other 1 1 1 2.2295855310379 0.37165971408571 2.59659416502913e-21 531.445237022051 67.3645207360498 7.88909697887379 4.97977772185261e-14 -596.556595631683 144.594999873339 -4.12570694805662 4.72796444090488e-05 CARM1 other 3.80115419818615e-17 0.682623505977846 7.11361247566645e-10 7.88909697887379 -4.12570694805662 1.07874275240921e-06 46.3075098412543 28.2418368187139 1.63967769300931 0.102057927003905 -204.003130415769 52.4448219169554 -3.88986220105391 0.000122093679152867 EVI5L other 0.0111434126323871 1 1 1.63967769300931 -3.88986220105391 0.00173113363352265 50.5839405892504 14.1667449585086 3.57061136749479 0.000410807129593753 -6.47092595640648 25.9173925209888 -0.24967503776339 0.80299886039324 SLC47A1 other 1 1 1 3.57061136749479 -0.24967503776339 1.17134698777865e-14 757.214033827663 91.1095443765555 8.31102865247684 2.73736955282217e-15 -252.660859958043 204.169043596882 -1.23750817218356 0.216805747106472 PSMB6 essential 1.60169987108852e-10 1 3.95276163427522e-11 8.31102865247684 -1.23750817218356 0.0434916778925207 -31.3586256520958 21.1475680191667 -1.48284784442705 0.139098998819325 -118.51979672603 51.3218667367158 -2.30934305905207 0.0215610132023671 SIGLEC10 other 1 1 1 -1.48284784442705 -2.30934305905207 0.681498372947327 -13.346089578263 19.4249753523892 -0.687058250327273 0.492543630176182 -31.9181708380254 46.8961117814003 -0.680614439568201 0.496607643718306 KLK3 other 1 1 1 -0.687058250327273 -0.680614439568201 5.08982514518455e-05 41.223242048477 14.0623140245578 2.93146931411762 0.00361659597500519 -90.6657541302961 33.4330547340178 -2.71185971044532 0.00705222433405939 ZNF473 other 0.453910606447558 1 1 2.93146931411762 -2.71185971044532 0.0195706715125424 34.3160566440639 14.4480890984968 2.3751277009798 0.0181318403319596 -33.2727550294084 34.3502323151398 -0.968632605571738 0.333460052757305 FAM71E1 other 1 1 1 2.3751277009798 -0.968632605571738 0.00127045351527119 2486.23753331731 1020.75161469319 2.43569297126668 0.0154105286240077 -5240.81667150637 2388.41891625341 -2.19426191772395 0.0289373590131194 RPS11 essential 1 1 1 2.43569297126668 -2.19426191772395 0.0113947758234577 1707.26897938849 869.996883934099 1.96238516587355 0.0505866170877061 -3702.37205733779 2035.67350250462 -1.81874551728582 0.0698878112215724 RPL13A other 1 1 1 1.96238516587355 -1.81874551728582 0.00457911056006268 19.6020748690742 6.23168960531807 3.14554737327513 0.00181393195057114 -5.44149045245611 15.1327344223304 -0.359584084448508 0.719396108323082 CTU1 other 1 1 1 3.14554737327513 -0.359584084448508 0.0887628908454194 60.2123531742017 109.404790810351 0.550363039207101 0.582455565961187 -505.484031346341 255.992219986574 -1.97460700709128 0.0491748884631704 NOSIP other 1 1 1 0.550363039207101 -1.97460700709128 0.620364625708509 12.3355632283124 12.6632002090398 0.974126841926303 0.330729348076503 9.11743634009495 30.7265514486913 0.296728266278749 0.766866477154506 IGLON5 other 1 1 1 0.974126841926303 0.296728266278749 0.000254495190696064 513.852104058565 124.774007084458 4.11826241751415 4.86800447602124e-05 205.575840088024 291.954080196905 0.704137582010758 0.481860786187155 RCN3 other 1 1 0.519902878039068 4.11826241751415 0.704137582010758 0.0305508331133805 34.9973669905553 13.2966228144972 2.63204931649244 0.00890246924752625 7.83323500116848 33.1275049053372 0.236457138065549 0.813230677808323 ZNF614 other 1 1 1 2.63204931649244 0.236457138065549 0.318674014885877 28.0079004970293 19.5125141048096 1.43538143504151 0.152155132519709 -2.09382732619322 44.024503793782 -0.0475604980353907 0.962096182908207 SLC2A5 other 1 1 1 1.43538143504151 -0.0475604980353907 0.00180165809509457 245.977527824442 77.5265326068059 3.17281735108644 0.00165617180267761 -115.706879885431 174.34269254388 -0.663674962208749 0.507376220789744 RERE other 1 1 1 3.17281735108644 -0.663674962208749 0.000237770691526534 30.5657499521894 9.59259693871284 3.18638947799789 0.00158315139645572 -34.4049733251409 21.2775895352421 -1.61695822114417 0.106875707957019 MMEL1 other 1 1 1 3.18638947799789 -1.61695822114417 0.515990107155619 0.357695800199162 5.66516675581826 0.063139500674327 0.949694840593199 13.9171025869526 12.4425035488106 1.11851304943232 0.264186880965464 PRDM16 og 1 1 1 0.063139500674327 1.11851304943232 0.181902131718044 -94.8772348146915 183.565525458249 -0.516857588470614 0.605612604532889 -656.822891405145 355.090676645826 -1.8497328558707 0.0652739232518504 PADI3 other 1 1 1 -0.516857588470614 -1.8497328558707 0.21744673829282 8.19759964445205 22.9368578799369 0.357398545492256 0.72102905930609 -69.4937763851469 46.385389382207 -1.49818245164509 0.135071631961175 FHAD1 other 1 1 1 0.357398545492256 -1.49818245164509 0.39276473581905 -61.8271535686873 73.8371225551444 -0.837345110821625 0.403023533892841 -184.632281134989 142.831142962355 -1.292661231337 0.197060816560727 PADI1 other 1 1 1 -0.837345110821625 -1.292661231337 2.59534042861745e-05 778.091887068645 314.031755100565 2.47774906336931 0.0137371479318953 -1849.00390141547 627.708734329867 -2.94563991273666 0.00345919843028436 EPHA2 other 0.23853773879423 1 1 2.47774906336931 -2.94563991273666 0.13540963336406 -71.9796636387023 81.8612047887256 -0.879289082349491 0.379904352389618 -325.936849671144 163.924635950951 -1.9883335276625 0.0476264307750684 ARHGEF19 other 1 1 1 -0.879289082349491 -1.9883335276625 0.00192324113410947 -105.707804867631 269.626127041049 -0.392053270310622 0.695279829969345 -1896.73792677705 545.267052526632 -3.47854857172836 0.000573942716400143 EFHD2 other 1 1 1 -0.392053270310622 -3.47854857172836 4.95760886173481e-13 64.6979918964434 16.4857805337834 3.92447247273862 0.000106569386698903 -186.608378385964 34.8826056370235 -5.3496112167694 1.688677085206e-07 PEX14 other 6.57230206800183e-09 0.0025485514569929 1 3.92447247273862 -5.3496112167694 0.410210996680889 -792.507358657492 594.348516091091 -1.3334051271292 0.183350255634366 -396.764107763195 1254.51790264996 -0.316268191091652 0.752005796710819 PGD essential 1 1 1 -1.3334051271292 -0.316268191091652 0.145955476904884 229.150175661631 133.284994324681 1.71924961862866 0.0865389775470085 -118.467703873302 259.667078393373 -0.456229201661959 0.648535617556698 MYOM3 other 1 1 1 1.71924961862866 -0.456229201661959 0.000227420250953178 1467.08382222156 443.171021633505 3.31042363016869 0.00103792889806815 -1326.36701565058 869.313293621707 -1.52576410067849 0.12805634592041 SH3BGRL3 other 1 1 1 3.31042363016869 -1.52576410067849 2.75037224708015e-10 122.114358740574 28.4760054060442 4.28832474918179 2.38649895915586e-05 -224.764515899372 55.8578265281736 -4.02386791376505 7.15037527452635e-05 CNKSR1 other 3.39698476236869e-06 1 0.260892066214919 4.28832474918179 -4.02386791376505 0.00424458610129236 1617.27435103724 919.44158997045 1.75897454354792 0.0795375477221163 -4003.90470736604 1803.85362552502 -2.2196394711354 0.0271439217431054 RPL11 essential 1 1 1 1.75897454354792 -2.2196394711354 4.72337044451949e-05 44.4604138570828 30.5665118337584 1.4545465344194 0.146778066296176 -222.731623466426 59.5499655813748 -3.74024772796995 0.000217905320480619 IL22RA1 other 0.422788888488939 1 1 1.4545465344194 -3.74024772796995 0.150456270183778 -20.704252314824 84.8326498948913 -0.244059950272411 0.807341281730821 -321.188652319571 166.272899259956 -1.93169574686622 0.0542825586189716 ZNF593 other 1 1 1 -0.244059950272411 -1.93169574686622 0.514934194262084 11.2090110118844 15.8737923437365 0.706133151370554 0.480622344213405 -28.9629789881821 37.8900506265278 -0.764395362615439 0.445198500129704 C1orf216 other 1 1 1 0.706133151370554 -0.764395362615439 0.00572350226495719 118.985423996364 47.4029540368479 2.51008458046461 0.012566510348103 -172.086941584994 113.702725136677 -1.51348124135227 0.131150676839822 KIAA0319L other 1 1 1 2.51008458046461 -1.51348124135227 0.181268248002868 39.7514043278577 24.3284320046196 1.63394847314079 0.103259251921658 -31.9440837026383 57.7852122447877 -0.552807240151993 0.580783787204697 EVA1B other 1 1 1 1.63394847314079 -0.552807240151993 0.0206077176204855 -41.2079432416892 20.0645372425493 -2.05376992967985 0.0408102011618309 -114.317598855413 49.3489799781737 -2.31651391591019 0.0211615105746402 DMRTA2 other 1 1 1 -2.05376992967985 -2.31651391591019 0.0132238283268433 26.4406770360215 22.1450428380984 1.19397723586847 0.23337397505305 -83.817539540763 39.8043014915185 -2.10574074660305 0.0360081154781772 PLK4 essential 1 1 1 1.19397723586847 -2.10574074660305 6.58031421724356e-08 220.360183737177 91.7867541725571 2.40078414062779 0.0169304789185113 -828.45464739322 180.437438453272 -4.59136781421206 6.33688381692836e-06 MAP3K6 other 0.000732652184947898 0.0937351854200042 1 2.40078414062779 -4.59136781421206 0.0773929567108966 -3.52752405932226 1.60641984708486 -2.19589173136998 0.0288170677364601 -0.012877597133474 3.182948089354 -0.0040458080911045 0.996774441969886 FCN3 other 1 1 1 -2.19589173136998 -0.0040458080911045 3.50029728625485e-08 50.0801090889431 19.0776084662167 2.62507269596326 0.00907893709031254 -170.946830753951 37.5033939754218 -4.55816961168856 7.35354830033385e-06 GPN2 essential 0.000395603599292524 0.10859720129933 1 2.62507269596326 -4.55816961168856 0.00265495390999327 82.9286180265069 94.7118439214955 0.875588676060879 0.381910429675414 -563.199629562143 186.18767666904 -3.02490282728682 0.00268857931473399 SYTL1 other 1 1 1 0.875588676060879 -3.02490282728682 0.00234363603254428 164.270506538729 88.4550397551496 1.85710737334404 0.0642145313980784 -417.850546546018 173.887844009561 -2.40298882837977 0.0168305959133926 WDTC1 other 1 1 1 1.85710737334404 -2.40298882837977 0.435792706551931 -14.436025100678 11.4583143970254 -1.25987336360971 0.208633094750679 -2.1756017227885 22.2810506140703 -0.0976435878393734 0.922276441585184 NBPF3 other 1 1 1 -1.25987336360971 -0.0976435878393734 0.504336291523383 871.228725720753 795.734648872136 1.09487343168432 0.274398062380268 1101.1264698197 1536.10318170935 0.716831058571463 0.474002843930486 HSPG2 other 1 1 1 1.09487343168432 0.716831058571463 0.000812988763185181 -6.85322335055998 18.2576703639912 -0.375361325619958 0.707640442713361 -160.818198055378 42.7094459131376 -3.76540118039577 0.00019783383514177 ITGB3BP other 1 1 1 -0.375361325619958 -3.76540118039577 1.73869839095599e-16 1152.58755068724 184.486002971072 6.24756096465468 1.32781261790377e-09 -1893.19135001604 413.041696978547 -4.58353566689507 6.56379491992171e-06 SERBP1 essential 2.4376551441203e-12 0.0970850906605621 1.76134343764935e-05 6.24756096465468 -4.58353566689507 3.83546481304652e-07 116.938791286964 34.3574101370696 3.40359738468162 0.000749620401371989 -229.641842854582 73.0091611154641 -3.14538394012504 0.00181441428705174 BCL10 other 0.00409129031607672 1 1 3.40359738468162 -3.14538394012504 0.189713588724549 495.218205688265 291.425220298035 1.69929769695915 0.0902349382825412 -74.5418750494018 619.275747996284 -0.120369440092863 0.904266038349333 CYR61 other 1 1 1 1.69929769695915 -0.120369440092863 0.120668567539629 31.8527291601138 34.7494852607852 0.916638877412656 0.360024351497862 -107.730253773163 73.6037788168453 -1.46365112640803 0.144273955752761 PRKACB other 1 1 1 0.916638877412656 -1.46365112640803 0.000224647988156085 35.9216817826275 22.8475024303989 1.57223669817115 0.116883848180371 -150.763109817224 47.8388663069283 -3.15147747962809 0.00177810477535418 PIGK other 1 1 1 1.57223669817115 -3.15147747962809 0.575297016834765 5.49541378112575 267.307456009198 0.0205584006640527 0.983610818161385 -582.909092766237 571.658691464791 -1.019680276832 0.308655238738763 TINAGL1 other 1 1 1 0.0205584006640527 -1.019680276832 0.335577713056058 -20.72053501984 14.0541448057802 -1.47433624074501 0.141383471165467 -15.4947689402428 33.1380460348231 -0.467582455645096 0.640404483454944 AZIN2 other 1 1 1 -1.47433624074501 -0.467582455645096 0.0139549421278469 1877.00988256308 741.793078199679 2.53036855927338 0.0118734401562983 -1912.83853811626 1882.6711417834 -1.01602372058685 0.310385660124298 RPS8 essential 1 1 1 2.53036855927338 -1.01602372058685 0.00871997510640437 70.3540027057549 60.4284662077143 1.16425266304001 0.24518890225025 -401.165443308921 153.367472432619 -2.615713990365 0.00932608337863348 KIF2C other 1 1 1 1.16425266304001 -2.615713990365 2.50250266396632e-12 4888.7081036536 661.976165092811 7.38502133678512 1.33165785262078e-12 -1284.83021010671 2087.83439691832 -0.615388946557801 0.538735291115226 PTPRF other 3.26626647700884e-08 1 1.86631848044802e-08 7.38502133678512 -0.615388946557801 0.466501815602838 26.6665270369646 32.2969814190476 0.825666234592365 0.409608573619786 -61.9506781349194 81.9609468782244 -0.75585605699461 0.450291534940413 MOB3C other 1 1 1 0.825666234592365 -0.75585605699461 0.342177445279205 -88.4139089800514 67.9773886700509 -1.30063703107508 0.194318584493054 -155.682440168673 172.508107473493 -0.902464483836477 0.367488968381512 CYP4B1 other 1 1 1 -1.30063703107508 -0.902464483836477 0.238657831108597 -2.42907607800402 4.18202667518643 -0.580837059796071 0.561761681752267 -16.8959496211481 10.0199067022752 -1.68623821789793 0.0927307180570891 TMEM61 other 1 1 1 -0.580837059796071 -1.68623821789793 0.0614566879049278 -494.12663552573 212.309876494704 -2.32738412213271 0.0205682645726554 -519.266588139583 451.156414804442 -1.15096798161379 0.250604700477454 LMO4 other 1 1 1 -2.32738412213271 -1.15096798161379 0.235612614584922 45.5036367070924 45.7953128552896 0.993630873335905 0.321153350379379 142.670266276955 85.0655427982599 1.67718046089836 0.0944836756039073 SYPL2 other 1 1 1 0.993630873335905 1.67718046089836 1.7111373406395e-07 52.4297600036557 17.6623207777176 2.96845248500979 0.00321892381321812 -137.592760637931 37.4776065560917 -3.67133265119266 0.000282650631422455 MTF2 other 0.00186359967769048 1 1 2.96845248500979 -3.67133265119266 0.0454702817946581 12.4215616631325 13.8326938168743 0.897985730587029 0.369870408435436 -56.8312392890369 29.4443317454609 -1.9301249483374 0.0544776674120311 SLC44A3 other 1 1 1 0.897985730587029 -1.9301249483374 0.00170593667598634 583.562765296621 289.581819392381 2.01519130766251 0.0447283932065643 -956.602248334884 535.481664198654 -1.78643324746971 0.07498471154132 IGSF3 other 1 1 1 2.01519130766251 -1.78643324746971 5.47091645515908e-05 46.6156375642104 13.5121049561793 3.44991677576427 0.000638456325583656 -27.5550985270608 25.1365638071157 -1.09621580493275 0.273835204117283 ZNF697 other 0.485968171227509 1 1 3.44991677576427 -1.09621580493275 3.64296648897381e-07 154.526887265963 53.5017551766282 2.88825827780443 0.00413865441410256 -286.217268746559 97.8534552396278 -2.92495822498713 0.00369187322513801 CTTNBP2NL other 0.003894331176713 1 1 2.88825827780443 -2.92495822498713 1.99190380202356e-17 75.7287258989054 24.9896483621068 3.0304038216775 0.00264144142946618 -306.695779051589 46.3652764546432 -6.61477300478546 1.56341004652744e-10 STRIP1 essential 2.82272687784758e-13 2.3899849381265e-06 1 3.0304038216775 -6.61477300478546 3.97487633347207e-11 29.56586269106 103.834005830287 0.284741616724144 0.776026287944724 -1227.22240729948 192.873364459411 -6.3628402539623 6.84926641170863e-10 PSMA5 essential 5.0393482155759e-07 1.04601996639614e-05 1 0.284741616724144 -6.3628402539623 0.431155279307393 -8.13614107582701 11.678007968853 -0.696706244551923 0.486492431718453 -27.6635618145883 21.4010659128907 -1.29262542002291 0.1970731930364 C1orf162 other 1 1 1 -0.696706244551923 -1.29262542002291 0.492286532690725 -73.792795726941 62.8494280092777 -1.17412040275129 0.241219857137773 -81.1881477621449 116.609528171075 -0.696239398576723 0.486784303870107 CD53 other 1 1 1 -1.17412040275129 -0.696239398576723 5.63603216019787e-05 405.2440145003 312.079888739371 1.2985265283747 0.195044391650039 -1926.94782020333 579.086126632684 -3.32756688786226 0.000978471985220111 CELSR2 other 0.499916052609551 1 1 1.2985265283747 -3.32756688786226 0.0955280965610837 4.95786715437761 2.29719637018975 2.15822522563366 0.031687909795513 -3.11293817346137 8.86312057215683 -0.351223719469703 0.725662217115842 ITGA10 other 1 1 1 2.15822522563366 -0.351223719469703 1.46098834435376e-07 338.734602660076 58.9188773723527 5.74916932852196 2.10343608284416e-08 -77.1640978669243 194.23864254536 -0.397264400408402 0.691439003240858 GPR161 other 0.00159759075455084 1 0.000268966371913282 5.74916932852196 -0.397264400408402 0.472883547700016 53.0199986854249 82.1423055091778 0.645465188209271 0.519089755885753 -283.845164983917 268.239330727655 -1.05817876973495 0.290774574862138 ALDH9A1 other 1 1 1 0.645465188209271 -1.05817876973495 0.0584628927689691 840.637707879353 475.753558663694 1.76696042009765 0.0781910203932598 -2594.16414905841 1541.76979173045 -1.68258851806064 0.0934332423383812 ATP1B1 other 1 1 1 1.76696042009765 -1.68258851806064 1.47001978915928e-06 170.185382399177 32.2662772875652 5.27440401266133 2.46707286111611e-07 -68.8478481955746 106.372663225076 -0.647232532383794 0.517948395620518 TIPRL essential 0.0150265422847862 1 0.00302389120587001 5.27440401266133 -0.647232532383794 0.0542271263941545 87.4630456606108 43.7319096917071 1.99998230759167 0.0463496840218865 -205.3947536813 141.721561656294 -1.44928373128873 0.148240695112334 NME7 other 1 1 1 1.99998230759167 -1.44928373128873 9.08142068179541e-12 406.100369913322 54.761685977987 7.41577551276573 1.1064327677907e-12 22.4861239122831 181.781045026546 0.123698947318734 0.901631793214488 POGK other 1.16914209857434e-07 1 1.55254645976391e-08 7.41577551276573 0.123698947318734 0.0813707977631601 72.9957078028202 32.4623377139144 2.24862757716712 0.0252205712435688 -12.0133069172352 107.019018226552 -0.112253944357851 0.910692882535634 MPC2 other 1 1 1 2.24862757716712 -0.112253944357851 0.0245007924510915 440.348745674172 160.953795687248 2.73587052603483 0.00657207229722483 22.9689241873893 530.597993011717 0.0432887505981993 0.965498612513859 CREG1 other 1 1 1 2.73587052603483 0.0432887505981993 0.000764454374027163 261.15285309455 73.729434239669 3.54204336148345 0.000456458353383628 -386.184115552507 243.064801317324 -1.58881135178573 0.1130966929183 DCAF6 other 1 1 1 3.54204336148345 -1.58881135178573 6.9851409115913e-05 15.8525460853181 3.57454397310399 4.43484433387803 1.27086601427525e-05 -4.73308797395541 11.7842464082695 -0.401645367041376 0.688214824421241 TBX19 other 0.612946114992137 1 0.141574473990262 4.43484433387803 -0.401645367041376 0.0001617950507437 220.884446006693 52.1487969668555 4.23565755787389 2.9851819700078e-05 -29.9988216455248 170.294202359329 -0.176158795953757 0.860280967637515 TMCO1 other 1 1 0.324071354664046 4.23565755787389 -0.176158795953757 0.00684430799083632 10.4427439348455 3.28382830598688 3.18005174503396 0.00161708603210055 -2.55112726054732 10.6418694956707 -0.239725478834819 0.810697043573207 XCL1 other 1 1 1 3.18005174503396 -0.239725478834819 0.224474274679594 41.3928612879232 23.9430848554449 1.72880234680829 0.0848181089359778 -14.1088720705743 78.9304329019614 -0.178750724553845 0.858247624389304 POU2F1 other 1 1 1 1.72880234680829 -0.178750724553845 0.329124703220218 2.54171972424978 2.15586978693136 1.17897645751028 0.239288912800178 6.20746323505382 7.10728444928922 0.87339451225631 0.383107130903094 ILDR2 other 1 1 1 1.17897645751028 0.87339451225631 0.156135016256858 106.287754685181 59.1412329954326 1.79718530206141 0.0732519373651316 -149.680269237583 191.658401324762 -0.780974213512048 0.435396831921118 DPT other 1 1 1 1.79718530206141 -0.780974213512048 0.000107428541029961 196.71258962686 48.3547155969005 4.06811594688543 5.97863706903759e-05 -254.348217083951 157.904461882793 -1.61077283093333 0.108218241411224 MGST3 other 0.922488881824273 1 0.633137665611081 4.06811594688543 -1.61077283093333 5.17071672840367e-07 173.231090363455 33.1597691925535 5.22413438276755 3.16553994673201e-07 162.932330300576 104.792226106659 1.55481314171855 0.120982096406547 RFWD2 other 0.00546131100853995 1 0.00385879319506632 5.22413438276755 1.55481314171855 0.000253788523800618 667.958434901257 162.029956830893 4.12243789954466 4.78497476830377e-05 -54.5159063669763 556.702103655563 -0.0979265319979925 0.922052132482199 NECTIN4 other 1 1 0.511657351974722 4.12243789954466 -0.0979265319979925 1.09853589582418e-09 324.582295542887 49.0613276240548 6.61584818963897 1.56638900159171e-10 -123.225979998991 168.436201016184 -0.731588454593266 0.464958564014818 UFC1 other 1.32505399754312e-05 1 2.12026415255454e-06 6.61584818963897 -0.731588454593266 5.35773908502184e-08 66.2331223065781 11.1903594958522 5.91876626761883 8.39503384367472e-09 -26.837080322726 38.3891464094917 -0.69907989191681 0.485013090123986 PPOX other 0.000599531003613943 1 0.0001086988982079 5.91876626761883 -0.69907989191681 0.000575438661846672 89.1450010279842 24.822932716268 3.59123565482502 0.000380788295516854 122.369377648441 85.2229585911485 1.4358733804995 0.152015169723903 NUF2 essential 1 1 1 3.59123565482502 1.4358733804995 0.492030347554654 -16.3832112860294 35.189030753828 -0.46557722492107 0.641834852548549 -130.902971358555 120.812208012422 -1.08352436820868 0.279391461090793 RGS5 other 1 1 1 -0.46557722492107 -1.08352436820868 3.32122259621365e-06 258.793773862696 51.2674133265793 5.04791946912066 7.50949835516733e-07 -180.44182365855 176.013071982545 -1.02516149298527 0.306061316016815 SDHC ts 0.0330063101611712 1 0.00899938282883253 5.04791946912066 -1.02516149298527 2.28792552544079e-08 306.257393100141 50.2135873538873 6.09909407471226 3.0832340436606e-09 -37.6434477163353 172.523712643931 -0.218192891512989 0.827418336201569 PFDN2 essential 0.000261166698729066 1 4.0498279163482e-05 6.09909407471226 -0.218192891512989 0.112295315596491 12.4588261105338 6.19333400245249 2.01165093075882 0.0450947197088693 11.4371266656456 21.2631703620681 0.537884354538617 0.591030774062986 NR1I3 other 1 1 1 2.01165093075882 0.537884354538617 3.8744564628036e-09 124.253720361173 19.3698992798197 6.41478401958573 5.10588593114664e-10 1.58661304768564 66.5002845776906 0.0238587407221098 0.980980249206296 USP21 other 4.5827071042041e-05 1 6.8418871477365e-06 6.41478401958573 0.0238587407221098 9.70682783895618e-10 295.073478932738 44.6008823834106 6.61586639466335 1.55327840951362e-10 74.9393417801989 156.565517077334 0.478645254581718 0.632517889031012 PRCC other 1.17384669056497e-05 1 2.10282831079954e-06 6.61586639466335 0.478645254581718 0.0121390360795281 -39.8127661534048 13.3113416559267 -2.99089056403859 0.00299828233014297 6.45748666681233 46.7269608813697 0.138196162237184 0.890172580991535 FCRL5 other 1 1 1 -2.99089056403859 0.138196162237184 5.21352146185386e-07 90.3458321757654 16.4286448255269 5.49928695490365 7.81075181746492e-08 3.55828162862153 55.0727363647889 0.0646105834482655 0.94852440071009 RRNAD1 other 0.0055049573115715 1 0.000976968837328512 5.49928695490365 0.0646105834482655 0.000775500984938027 198.049477357967 51.7451276370698 3.82740339819137 0.000155754910707697 -12.7900113441683 173.462011187359 -0.0737337890678184 0.941268280219391 MRPL24 other 1 1 1 3.82740339819137 -0.0737337890678184 4.95794287988161e-10 76.6457857091977 11.3598917036813 6.7470524991325 7.08028521138508e-11 15.5815598757875 39.7637188367387 0.391853688025561 0.695427151677643 PIGM other 6.06852208497509e-06 1 9.64476451494875e-07 6.7470524991325 0.391853688025561 0.501796550490637 140.128895409103 136.429246227743 1.02711771327376 0.305140797258735 -286.193531361253 477.551576160726 -0.599293449436613 0.549401265271447 CASQ1 other 1 1 1 1.02711771327376 -0.599293449436613 2.42318484497749e-08 235.506815182665 38.7431606337311 6.07866811407287 3.44594562804706e-09 24.6377448256708 129.876316286588 0.189701598644857 0.849663240457623 ISG20L2 essential 0.000276259399763579 1 4.51901309662092e-05 6.07866811407287 0.189701598644857 0.541166877030362 -55.2218363661628 417.869545009032 -0.132150899786126 0.894947989561597 -1537.74202435525 1400.7983939977 -1.09776112747154 0.273134134244171 CRABP2 other 1 1 1 -0.132150899786126 -1.09776112747154 0.000194661423455031 1202.31359100801 288.582469298504 4.16627383475731 3.98787637326637e-05 -526.270712753315 967.397275914182 -0.544006816905696 0.586815606107326 HDGF other 1 1 0.429015740235996 4.16627383475731 -0.544006816905696 0.00831970966739826 159.357312277299 56.0715109800288 2.84203706110324 0.0047703897909383 -242.649301082302 176.136115906951 -1.37762377598067 0.169282169494464 ABL2 other 1 1 1 2.84203706110324 -1.37762377598067 0.00118351023770163 367.344616257276 103.648330797414 3.54414406320996 0.000452588964894678 -394.5263021604 325.344381279941 -1.21264212588608 0.226161148489816 XPR1 other 1 1 1 3.54414406320996 -1.21264212588608 0.00454036893418556 102.214215298316 31.9021157653498 3.20399487137888 0.0014927538362865 -94.8628856706926 100.460526034457 -0.944280200545188 0.345743362382939 RGS16 other 1 1 1 3.20399487137888 -0.944280200545188 0.00115073115977889 149.934869438737 43.2936209705573 3.46320926911387 0.000606413473460375 -199.745757624733 135.997231178908 -1.46874870828775 0.142883287957642 TOR1AIP1 other 1 1 1 3.46320926911387 -1.46874870828775 0.547050753826879 9.16053220696932 67.0359387130429 0.13665106184583 0.891393631981814 -237.862347624076 217.205786963495 -1.09510133661426 0.274306205063495 HMCN1 other 1 1 1 0.13665106184583 -1.09510133661426 0.701437768729697 19.66065606918 24.0279006097084 0.818242774869653 0.413829357493994 14.5991900927625 82.4927285110481 0.176975478399981 0.859639961404271 RGL1 other 1 1 1 0.818242774869653 0.176975478399981 0.00488202862525897 47.3103961983064 14.5539077991498 3.25070055762413 0.00127417468087123 17.9638100087195 47.3824073936874 0.379124046177374 0.704847978256902 LYPLAL1 other 1 1 1 3.25070055762413 0.379124046177374 0.984648673436377 2.4955944161362 14.6035092905942 0.170890048855829 0.864418902656238 2.23137601829988 50.2477734181752 0.0444074605998913 0.96460748659313 LHX9 other 1 1 1 0.170890048855829 0.0444074605998913 1.62568991079706e-12 161.312125343305 20.9626901333522 7.69520153745216 1.80560898408127e-13 -16.0263566641085 83.5798886671847 -0.191748959225412 0.848061618634718 PRUNE1 other 2.13209231801034e-08 1 2.55963129583361e-09 7.69520153745216 -0.191748959225412 0.119565886011756 32.7873068669527 17.0954372034994 1.91789811963634 0.0560165433236267 -54.0073371897742 65.3358201173904 -0.826611452840693 0.409075170252962 RORC other 1 1 1 1.91789811963634 -0.826611452840693 0.0235929601696583 267.306493646348 97.2541732966029 2.74853494287721 0.0063270659695239 -92.3191330567749 371.029480237937 -0.248818862041829 0.803661017319718 TUFT1 other 1 1 1 2.74853494287721 -0.248818862041829 3.3123107642681e-13 470.466749172455 59.6201401223413 7.89107083960305 4.99246807251146e-14 -257.350937882085 246.886604940413 -1.04238517899421 0.298032474135337 SF3B4 essential 4.40437962324729e-09 1 7.13124139477537e-10 7.89107083960305 -1.04238517899421 0.33853078552335 -617.41402561781 514.789575747924 -1.19935222992965 0.231286703007062 -1775.92879857486 2133.0337566779 -0.832583541172261 0.405706449132555 ECM1 other 1 1 1 -1.19935222992965 -0.832583541172261 1.90673233391388e-10 233.954830961461 33.9304851338494 6.89512189520878 2.92092959236314e-11 -123.380095611655 135.283503780781 -0.912011384710918 0.362455758850329 ZNF687 other 2.3668268460873e-06 1 4.00751540072222e-07 6.89512189520878 -0.912011384710918 0.295747470965697 47.0501839173421 40.0812406640764 1.17387044756606 0.241325316208715 -168.347745048006 157.754692363494 -1.06714889126787 0.286714086080499 CGN other 1 1 1 1.17387044756606 -1.06714889126787 4.34108518149397e-09 177.845563213439 27.9141040827756 6.37117217468493 6.55065566504853e-10 41.7901366245578 106.493687397389 0.392418909006456 0.695010782259203 SNX27 other 5.12465105675363e-05 1 8.75888168973639e-06 6.37117217468493 0.392418909006456 3.07956577127488e-15 244.720791390251 28.4397688424853 8.6048797634624 3.64365039396019e-16 -94.7016738478187 113.316453768278 -0.835727475565687 0.4039396913746 SETDB1 other 4.24610528543381e-11 1 5.29240219722717e-12 8.6048797634624 -0.835727475565687 0.792868687198063 -8.37190968926375 79.4889136488461 -0.10532172733229 0.9161873449234 -212.337972884567 316.718530958107 -0.670431162465367 0.503072644306803 ADAMTSL4 other 1 1 1 -0.10532172733229 -0.670431162465367 0.000733047548469168 1089.25159949121 316.251194046926 3.44426082808586 0.000649899544458449 -2260.59027950101 1260.08280896595 -1.79400136516115 0.0737688297121066 MCL1 essential 1 1 1 3.44426082808586 -1.79400136516115 0.00445207710451644 531.655152817133 165.786878219538 3.20685906222992 0.00147932532046758 -619.987502537842 660.567293116916 -0.938568271541879 0.348669270749923 CTSK other 1 1 1 3.20685906222992 -0.938568271541879 0.656741648121681 26.9813831830893 51.100964561294 0.528001446053448 0.597867733237456 -155.705105734887 203.743551121018 -0.764221026276324 0.445304004615945 RFX5 other 1 1 1 0.528001446053448 -0.764221026276324 3.2122768465798e-20 452.709656656251 44.6553701706964 10.1378547513044 4.18903831059226e-21 -225.212657363368 178.044461064687 -1.26492369387186 0.206827768645783 PI4KB other 4.66840194113443e-16 1 6.24836954407941e-17 10.1378547513044 -1.26492369387186 1.7711009668724e-09 260.6830910521 39.9560753593025 6.52424165056061 2.70303471215071e-10 -129.709487432083 159.308004309756 -0.814205714233155 0.416138311640829 PIP5K1A other 2.12018496744294e-05 1 3.64098775726701e-06 6.52424165056061 -0.814205714233155 8.0853430907364e-08 390.32610637095 66.9936223644275 5.82631738059602 1.39591922681256e-08 156.362232080904 277.41016518972 0.563649972862271 0.573392135306229 ANP32E other 0.000896664548762666 1 0.000179557090144899 5.82631738059602 0.563649972862271 5.49422716127285e-08 89.9203666466072 15.1582048748367 5.93212503651267 7.82449937921991e-09 6.56791328470146 60.4369509721237 0.108673802682913 0.913529976592272 MINDY1 other 0.00061436448117353 1 0.000101436809952207 5.93212503651267 0.108673802682913 0.736591707408546 -11.0974731205541 22.6050193994767 -0.490929599503507 0.623815921212985 -53.7077619499461 90.1279841808971 -0.59590550524406 0.551663588959541 ANXA9 other 1 1 1 -0.490929599503507 -0.59590550524406 0.220543068361785 49.4461042610818 46.0117085348798 1.07464177783354 0.2833524207251 -256.863949812948 183.452288435713 -1.40016759672616 0.16244109563153 SELENBP1 other 1 1 1 1.07464177783354 -1.40016759672616 2.9829502691636e-11 673.624724741745 93.1082634897498 7.23485434583262 3.54989747835066e-12 7.43661034537368 370.98396592519 0.0200456381634383 0.98401961695716 CERS2 other 3.79341785729535e-07 1 4.94500718734247e-08 7.23485434583262 0.0200456381634383 3.15655092243484e-06 588.9133741239 114.780785331302 5.13076620293256 5.04674426717592e-07 -163.315245099144 457.33675356218 -0.357100634985244 0.721254825369772 ENSA other 0.0314329340856062 1 0.0060989904468821 5.13076620293256 -0.357100634985244 1.43524418189593e-07 253.861923871573 44.182244824466 5.74579052920816 2.14723288991061e-08 -87.5522540054761 176.158073224577 -0.497009602812012 0.619526793811264 SEMA6C other 0.00157030065941234 1 0.000274416363330576 5.74579052920816 -0.497009602812012 2.36925360090807e-09 181.010843244401 27.8362024688953 6.50271327228152 3.04341448626688e-10 -33.0312970804859 106.46193482665 -0.310263918594662 0.756562871082542 MRPL9 essential 2.82628262052323e-05 1 4.09613155706659e-06 6.50271327228152 -0.310263918594662 9.50152351067771e-14 233.245244040625 28.8551394451354 8.08331716726283 1.35409775837041e-14 -120.044823930158 114.971471569322 -1.04412705422994 0.297224691438681 ARNT og 1.27804992742126e-09 1 1.94380733214072e-10 8.08331716726283 -1.04412705422994 4.05698593538833e-08 289.49434675663 48.4110479357379 5.97992316012066 6.01589418337373e-09 46.157731819977 189.962958333642 0.242982801620238 0.808175868585889 POGZ essential 0.000456816616324726 1 7.83449899500761e-05 5.97992316012066 0.242982801620238 6.09480805661215e-08 113.57011017702 19.3997613557974 5.85420140454878 1.19697484133414e-08 55.3580662512604 77.3483691249991 0.715697911636623 0.474704734969342 C1orf56 other 0.000679936786795652 1 0.00015425414780273 5.85420140454878 0.715697911636623 7.16141875228601e-06 21.851944712311 4.49208682135809 4.86454193369855 1.80548046758005e-06 -18.9903484130646 17.1803698778764 -1.1053515464483 0.269840250721399 OAZ3 other 0.0692365964971012 1 0.0212035626112602 4.86454193369855 -1.1053515464483 0.0310879008470871 28.6604367344175 10.8853109360064 2.63294607778401 0.00888083611504878 9.7801664824382 43.3718304907821 0.225495820023478 0.821739341013048 HORMAD1 other 1 1 1 2.63294607778401 0.225495820023478 0.0553275025819045 67.9644329029266 30.2782346427688 2.24466299653168 0.0254813576402156 -115.133670960319 120.641704054812 -0.954343871900299 0.340639068860496 GOLPH3L other 1 1 1 2.24466299653168 -0.954343871900299 0.0105765387234902 49.2784380782006 16.7083912609996 2.9493227270315 0.00342159222407096 43.3510827324868 66.6176656010509 0.650744548632202 0.515682787366631 GABPB2 og 1 1 1 2.9493227270315 0.650744548632202 0.34268561492686 3.74619563262218 9.74897275778441 0.384265678620437 0.701036765952455 46.7369420361108 32.9002755101302 1.42056384973798 0.156417212669789 SYT14 other 1 1 1 0.384265678620437 1.42056384973798 0.572946569615049 6.71839087351554 8.57655344290733 0.783343905945289 0.434004558322116 20.8651000174546 28.9436618820888 0.720886669504887 0.471505551434449 KCNH1 other 1 1 1 0.783343905945289 0.720886669504887 0.114698943300769 75.6347127787574 38.9299332092122 1.94284208946085 0.0529120809322554 104.535596034211 131.37851135663 0.79568260406336 0.426806364728111 DTL essential 1 1 1 1.94284208946085 0.79568260406336 0.0168229745365258 30.8482939383892 11.4987288622445 2.68275687756045 0.00768113717072992 -38.8023358017674 39.0500506473159 -0.993656478251827 0.321140899794871 DYRK3 other 1 1 1 2.68275687756045 -0.993656478251827 9.24370630570131e-09 198.021347480777 31.7137156048447 6.24402860731102 1.35483057035995e-09 -41.0008000042097 107.700791576194 -0.380691723841261 0.703684602521842 EIF2D other 0.000107485816922695 1 1.79691178546841e-05 6.24402860731102 -0.380691723841261 0.00388511493638946 88.4956889832237 26.7258198709534 3.31124318769371 0.00103499501980401 56.6208303853725 90.19276787766 0.627775726565733 0.530598595430468 INTS7 essential 1 1 1 3.31124318769371 0.627775726565733 0.79187529410507 3.56906593993802 8.58161061671138 0.415896980106253 0.67776503323937 -14.7800666167931 27.487302507549 -0.537705240910198 0.591155470835901 VASH2 other 1 1 1 0.415896980106253 -0.537705240910198 2.07929680861107e-08 35.5237503276892 5.82486586481004 6.09863834673001 3.08159450399424e-09 -13.0623473455307 19.0743186752851 -0.684813311966727 0.493957442113183 TAF1A other 0.000237809176000848 1 4.04798254044683e-05 6.09863834673001 -0.684813311966727 0.0491305536224877 78.3332731905636 31.7613469216514 2.46630828924842 0.0141784921279848 7.53615531433313 103.491364585791 0.0728191704157683 0.94199579527179 SMYD2 other 1 1 1 2.46630828924842 0.0728191704157683 0.37584371163047 41.2593900319754 94.7405075131196 0.435498934035812 0.663493912882063 407.940128723776 310.240728920616 1.31491480871346 0.189480055450188 SUSD4 other 1 1 1 0.435498934035812 1.31491480871346 0.0382942340016515 76.3907675903265 33.7298909710279 2.26477955875819 0.024194735572592 -142.639887305912 110.453133891176 -1.29140642986597 0.197494819971981 DUSP10 other 1 1 1 2.26477955875819 -1.29140642986597 0.00419635935450155 30.7209786861759 9.20730646939184 3.33658695822743 0.000947985521721867 -1.8543641550397 30.1505823162712 -0.0615034275486933 0.950996679987195 HHIPL2 other 1 1 1 3.33658695822743 -0.0615034275486933 5.84000571956611e-06 205.984807164112 42.1542086893866 4.88645887488748 1.62602385081105e-06 -172.912345555121 138.039712622988 -1.25262753934715 0.211255917193608 TP53BP2 other 0.0569283757543304 1 0.0191675691533606 4.88645887488748 -1.25262753934715 0.0415757468610182 94.2575310823002 39.6675257954178 2.37618881420601 0.0180807048081164 -137.447504182837 140.427237681128 -0.978780943444488 0.328427605709493 ATP8B2 other 1 1 1 2.37618881420601 -0.978780943444488 0.29663988055054 -58.8087300408468 45.3935622192059 -1.29553018458562 0.196079985627631 -179.657875974749 203.266120847543 -0.883855485732906 0.377444062564956 FLG2 other 1 1 1 -1.29553018458562 -0.883855485732906 0.204781005499076 2134.25716057268 1230.28151688512 1.73477137653526 0.0837502328600211 2393.57837465923 5319.50743183772 0.449962408236044 0.653044119694427 CRNN other 1 1 1 1.73477137653526 0.449962408236044 0.0228703649776725 430.618979346838 163.717261519917 2.63026009199678 0.00894711346033484 -554.181456885279 573.91362503568 -0.965618226698879 0.334969011272802 ADAM15 other 1 1 1 2.63026009199678 -0.965618226698879 3.12394367764007e-08 574.517857824711 95.1082978685291 6.04067016969312 4.25917518483737e-09 -5.26391902827331 338.326674589666 -0.0155586875751301 0.987596160064709 JTB other 0.000354067776423726 1 5.56929747169335e-05 6.04067016969312 -0.0155586875751301 3.7133801059985e-05 236.917501841333 52.9169776471887 4.47715482582781 1.05345897117656e-05 -205.705479650567 188.240410962429 -1.0927806553271 0.275312105282778 RAB13 other 0.335912364388624 1 0.117987404771775 4.47715482582781 -1.0927806553271 0.226237996674131 -9165.48062396133 5476.48135521041 -1.67360756468953 0.0951879713702281 -7366.81638087321 20011.1181081663 -0.368136170155675 0.713015862268265 S100A8 other 1 1 1 -1.67360756468953 -0.368136170155675 0.0395458067729866 720.80631269894 304.319867485146 2.36858118615645 0.0184501428842005 -1135.03895793999 1077.32452441897 -1.05357200380465 0.292873775903816 TPM3 other 1 1 1 2.36858118615645 -1.05357200380465 0.000806855602279648 85.9551057291631 22.753936308861 3.77759278932717 0.000188793455004217 -49.8062092411912 81.7145548199664 -0.609514539373362 0.54261595860602 SNAPIN other 1 1 1 3.77759278932717 -0.609514539373362 3.62084779074964e-08 161.466678658525 26.9314906219485 5.99546014459867 5.47325285921876e-09 34.8323124152082 95.8028044667763 0.36358343170724 0.716409183047231 SLC27A3 other 0.000408974757965172 1 7.13438510199165e-05 5.99546014459867 0.36358343170724 0.232014830584978 -3070.77286599184 1915.11057165925 -1.60344416214638 0.109826241817893 -3805.16888502795 6997.83334480077 -0.543763861975236 0.586983794135397 S100A7 other 1 1 1 -1.60344416214638 -0.543763861975236 6.32494821343217e-07 586.226325750971 107.326005296411 5.46210887223411 9.46489621874719e-08 -144.792363864199 379.94541259909 -0.381087280074573 0.703391368278864 UBAP2L other 0.00664056312928244 1 0.0011800832605534 5.46210887223411 -0.381087280074573 4.33222120739916e-07 501.890771804902 90.7814189864632 5.52856275445244 6.7095739982227e-08 -145.90681957973 322.934762671053 -0.451815154159644 0.651708233141964 SLC39A1 other 0.00460081892225791 1 0.000841112196417198 5.52856275445244 -0.451815154159644 3.66295710645553e-07 229.265647436086 41.2385615412691 5.55949671538981 5.71039724420454e-08 22.7299736680139 145.988870418849 0.155696619905343 0.876370330616671 HAX1 other 0.00391423596395838 1 0.000717911141541394 5.55949671538981 0.155696619905343 0.00110980658182543 94.6362082663775 25.4370451904144 3.72040885873174 0.00023485888063694 -28.1887024732515 90.4866463129886 -0.311523342082414 0.755605657129219 CREB3L4 other 1 1 1 3.72040885873174 -0.311523342082414 0.000437355262827237 151.583738597176 38.1478668964881 3.97358360844891 8.7645515900913e-05 10.5691280710197 133.727991628291 0.0790345233060671 0.93705487352339 EFNA3 other 1 1 0.914493312910126 3.97358360844891 0.0790345233060671 0.0370577349107121 27.2918742967557 10.9750049643714 2.48673001837852 0.0134017567315462 -30.724040250119 38.8526786024393 -0.790783064521838 0.429656270162567 KCNN3 other 1 1 1 2.48673001837852 -0.790783064521838 7.91668375365317e-07 556.019186857547 103.126365140794 5.39162983295723 1.35850493521456e-07 -280.320775753916 365.078242174861 -0.767837530070201 0.443149926757954 C1orf43 other 0.00825710115506026 1 0.0016829159137438 5.39162983295723 -0.767837530070201 1.37388303258506e-07 195.300482541955 33.9401701174068 5.7542576205825 2.03663352445636e-08 -51.3997765097906 120.734627242545 -0.425725226339028 0.67059426140873 GATAD2B other 0.0015045393089839 1 0.000260668724795169 5.7542576205825 -0.425725226339028 1.11490987431029e-09 901.303550665504 136.148253919034 6.62001549576609 1.5154148232712e-10 -262.261374551338 488.939311752276 -0.53638839882078 0.592062826274463 ILF2 essential 1.34424683545591e-05 1 2.05202321219153e-06 6.62001549576609 -0.53638839882078 0.00021630106594889 200.400290526165 49.7857061323049 4.02525757078958 7.11031183251048e-05 168.918833246921 173.357504197368 0.974395853407112 0.330596020318344 RIT1 other 1 1 0.748289217253402 4.02525757078958 0.974395853407112 3.96613226372529e-10 323.629902792724 47.7206194917551 6.78176239620357 5.7408555944669e-11 84.0880516657419 171.375586385166 0.490665289259779 0.62399948977102 INTS3 essential 4.87160025953377e-06 1 7.83052703085285e-07 6.78176239620357 0.490665289259779 0.0769348584956465 15.2437852532418 7.14725506561723 2.13281674059374 0.0337028921503109 18.281942344595 24.7314573309264 0.739218158475992 0.460318121791823 HCN3 other 1 1 1 2.13281674059374 0.739218158475992 0.500529435377809 -96.3850084693419 130.864869541943 -0.736523169332699 0.461955360940362 -542.301416417387 585.934601093739 -0.925532329726042 0.355390904183414 FLG other 1 1 1 -0.736523169332699 -0.925532329726042 0.571268040358573 2862.95417530756 2915.4840769855 0.981982442609581 0.326850339375773 -4225.01259728254 9811.12133796253 -0.430635036683783 0.667023664988886 ACTA1 other 1 1 1 0.981982442609581 -0.430635036683783 3.53022352703099e-07 65.9845063025206 11.9814702990492 5.5072127756939 7.4963852685138e-08 28.8247674069627 40.4244547637583 0.71305271958312 0.476332786737837 C1orf131 other 0.00377945730803938 1 0.000938697363323298 5.5072127756939 0.71305271958312 0.0101947475712167 590.966993828779 200.885270499862 2.94181346575724 0.00350107086463057 -613.169377907408 677.769699990113 -0.904686913440291 0.366311873232173 GALNT2 other 1 1 1 2.94181346575724 -0.904686913440291 0.0014664343101384 42.7152048319326 12.3700674575531 3.45311009648948 0.000628720971125708 44.4373812024812 41.7355482992916 1.0647369691615 0.287797713470231 TTC13 other 1 1 1 3.45311009648948 1.0647369691615 0.00575629453729889 122.720124507026 37.9566245029862 3.23316749352595 0.00135192783671009 31.0850038664234 120.600856667487 0.257751103312053 0.796764679649622 SCCPDH other 1 1 1 3.23316749352595 0.257751103312053 0.20884559225994 57.4020326223338 37.7147044463799 1.52200669380676 0.128998027773576 -120.952358845672 122.953869193163 -0.983721452926817 0.325997993085431 LYST other 1 1 1 1.52200669380676 -0.983721452926817 2.85469417752821e-07 119.119295850257 21.5508861919452 5.52735023466362 6.75202035280507e-08 55.796261070845 69.2079629830054 0.806211578348957 0.420719590383531 MAP3K21 other 0.00307022358793159 1 0.000846365751224116 5.52735023466362 0.806211578348957 3.04890100308897e-06 144.585967676357 45.0567975608833 3.20897124304018 0.00147019276424996 -440.45192780946 139.691412145809 -3.15303511535641 0.0017724454181137 ACP1 other 0.0304066897038063 1 1 3.20897124304018 -3.15303511535641 8.76880392848967e-13 251.175600709033 32.9982179925127 7.61179287821011 3.05875914533728e-13 154.165889011855 111.333161726305 1.38472568838786 0.167101064661755 SNAP47 other 1.15660523816779e-08 1 4.32080316870345e-09 7.61179287821011 1.38472568838786 0.0049773971414145 282.131773658709 93.0158372916185 3.03315845853415 0.00261812330218625 349.236885696312 304.593060771993 1.1465687524567 0.252416502079816 SRP9 essential 1 1 1 3.03315845853415 1.1465687524567 0.000295400884581481 54.1085204458076 14.6794712804101 3.68599927151436 0.000267485163661808 77.9321638352421 48.0699332286458 1.6212247157606 0.105954335012708 NVL essential 1 1 1 3.68599927151436 1.6212247157606 8.69186818756779e-05 123.891930914086 28.3603817440359 4.36848601095223 1.69238266380787e-05 -53.6207166675588 92.8699427065895 -0.577374283916234 0.56409263680438 SDE2 essential 0.753671890544003 1 0.186991360524131 4.36848601095223 -0.577374283916234 0.0577448698307866 267.62375461583 111.618872347308 2.39765685665685 0.0170730564273576 -4.19357061925891 365.511239355888 -0.0114731646190933 0.990853089349494 DEGS1 other 1 1 1 2.39765685665685 -0.0114731646190933 1.64111217761931e-05 148.878168194999 31.3441712457457 4.74978799176915 3.07869836298326e-06 -69.2142261918706 102.64076887435 -0.674334642568789 0.50058543248945 FBXO28 other 0.153722977677601 1 0.0357129010106059 4.74978799176915 -0.674334642568789 6.70669109295988e-06 156.297807345806 31.5208482044987 4.95855334640069 1.15445662505145e-06 20.820032510291 103.219321701497 0.201706736365708 0.840274158176345 CNIH4 other 0.0650079567640601 1 0.0137207169887365 4.95855334640069 0.201706736365708 0.618346395479371 68.0506820371538 70.1115630010255 0.970605690763997 0.332477727198832 27.4049094253525 240.329091597346 0.114030761915696 0.909284918110582 ITPKB other 1 1 1 0.970605690763997 0.114030761915696 2.60107038198371e-05 1057.76961331407 228.187226199566 4.63553385932733 5.19188713980126e-06 327.476138111495 769.884160536112 0.425357677034758 0.670861859138448 GUK1 essential 0.238986346696663 1 0.0594159564278856 4.63553385932733 0.425357677034758 0.00154033400953927 135.14655327016 37.2537473993168 3.62773043531826 0.000332656056750217 16.594985021021 128.027269313834 0.129620705885256 0.896947957184962 CDC42BPA other 1 1 1 3.62773043531826 0.129620705885256 0.198815858121125 13.1803494436249 7.84128981853272 1.68089048468448 0.0937599377975026 -18.2419328813251 25.6773742598172 -0.710428281986453 0.477956013483205 CNIH3 other 1 1 1 1.68089048468448 -0.710428281986453 4.31606799702744e-13 158.545118828781 20.8285470436654 7.61191447950755 3.05632311146168e-13 129.059044711635 70.2737340865654 1.8365189553277 0.0672083868475036 C1orf35 other 5.73001187285362e-09 1 4.31766765956192e-09 7.61191447950755 1.8365189553277 6.20208962632303e-05 545.610005457672 142.159598084679 3.838010326483 0.000149549034673465 -539.906157172674 427.90491230964 -1.2617433024045 0.207962963317096 MBOAT2 other 0.547024305041691 1 1 3.838010326483 -1.2617433024045 0.000966834240127143 594.406458089083 157.971059818929 3.76275539817488 0.000199848990191568 30.9345685539823 541.494721839221 0.0571281072674376 0.954478801220016 PARP1 other 1 1 1 3.76275539817488 0.0571281072674376 0.0538336860068926 31.829088421843 13.8341442620555 2.30076308435964 0.0220476763222825 -40.2124831169438 47.4208130758375 -0.847992274038705 0.397076103015463 PSEN2 other 1 1 1 2.30076308435964 -0.847992274038705 0.000291020080625481 237.566450034549 64.9862110623297 3.65564396125039 0.00029976698941696 360.326849989812 212.806222163991 1.693215763739 0.0913875876095203 LBR other 1 1 1 3.65564396125039 1.693215763739 0.361627780175158 39.6269367121847 27.9417446279513 1.41819837092578 0.157105951176977 11.6855945503199 94.2730536020057 0.123954768662243 0.901428910961748 WNT9A other 1 1 1 1.41819837092578 0.123954768662243 0.0288767558092293 533.090330774747 202.003903064381 2.63901005222084 0.00872175937864637 234.871629886656 661.489364755879 0.355064861811248 0.722774904899919 EPHX1 other 1 1 1 2.63901005222084 0.355064861811248 0.0265555716689854 163.967205090553 62.8616187317982 2.60838343648334 0.00952386379590814 165.544950236581 213.480065897461 0.775458586920692 0.43864140983447 SOX13 other 1 1 1 2.60838343648334 0.775458586920692 0.436867952173873 75.397154721867 60.9200724959598 1.23764059418786 0.216756686055954 -69.989899946842 206.886512840258 -0.338300931201266 0.735358269588834 ETNK2 other 1 1 1 1.23764059418786 -0.338300931201266 0.000662992501143079 41.3251254542537 10.7053341491461 3.86023685748753 0.000137052952702775 13.7522228730741 36.4104417257636 0.377699973448638 0.705903881796333 PPFIA4 other 1 1 1 3.86023685748753 0.377699973448638 0.417139972856967 22.9743419702209 21.7002011870845 1.0587156207517 0.290527817278172 -57.3110042684437 73.6945766409862 -0.777682794049317 0.437330607815275 PLEKHA6 other 1 1 1 1.0587156207517 -0.777682794049317 0.578183255733975 8.8892861564387 31.0729521487358 0.286077940515233 0.77500353466595 -105.676627033724 105.68375519126 -0.999932552003636 0.318098666365871 PTPN7 other 1 1 1 0.286077940515233 -0.999932552003636 0.419345147429752 13.4620815584982 11.9822625387546 1.12350080086773 0.262067009536158 -27.0313767967267 40.7534660601813 -0.663290252583891 0.507622207015028 SYT2 other 1 1 1 1.12350080086773 -0.663290252583891 3.66650353199052e-08 167.516713599456 29.5068937126157 5.67720598552311 3.07228067216179e-08 -183.341902267515 100.357356348115 -1.82689051345223 0.0686476123404111 ARL8A other 0.000413948248761729 1 0.000390243395989742 5.67720598552311 -1.82689051345223 0.000226021337205553 7.02338197259281 9.3230799845147 0.753332802492137 0.451807320635958 124.025417759488 29.8784947292675 4.15099284228661 4.25551709790183e-05 OSR1 other 1 0.615262662014647 1 0.753332802492137 4.15099284228661 0.0014145029908528 8.11506001884554 2.22050175477029 3.65460644262587 0.000301219477436787 6.16371595956994 7.29184669235984 0.845288747777444 0.398585182794279 GDF7 other 1 1 1 3.65460644262587 0.845288747777444 7.32557716844092e-11 1946.2131084892 298.340937370942 6.52345308572046 2.69413765596331e-10 -961.965026155866 898.083261922321 -1.07113122684951 0.284920152466028 PDIA6 other 9.20458771214602e-07 1 3.62927283634817e-06 6.52345308572046 -1.07113122684951 0.473569010607814 486.466672129132 402.768061335221 1.20780846057267 0.228018441403976 542.272741904325 1322.63933118992 0.409992905183356 0.682087215748878 RHOB other 1 1 1 1.20780846057267 0.409992905183356 7.96116999791909e-06 738.193988854934 152.010789265064 4.85619469791537 1.87775710720022e-06 158.404256541464 457.591729360344 0.34616940468503 0.729443609861656 ATP6V1C2 other 0.0766899505899546 1 0.0220354796529946 4.85619469791537 0.34616940468503 1.10676806341926e-05 86.2860452603464 19.563280946863 4.41061218180698 1.41117040679706e-05 -85.4632551078917 67.0052634935775 -1.27547077127879 0.20307070718686 HNRNPLL other 0.105154033705464 1 0.15666813856261 4.41061218180698 -1.27547077127879 0.855874629545195 -3.02931437744648 13.4515323030364 -0.225202178398863 0.821966192183573 -24.9395162404059 46.0722037783673 -0.541313724873652 0.588669191389817 GALM other 1 1 1 -0.225202178398863 -0.541313724873652 0.00359618588559861 17.3843524049041 5.16308716648161 3.36704608005885 0.000852730446021866 14.6798307660066 18.7201461277143 0.784172872682536 0.433520571995077 CAMKMT other 1 1 1 3.36704608005885 0.784172872682536 2.99634004984636e-05 277.608205999683 69.7192448746569 3.98180167468501 8.47530701953103e-05 -435.876991613501 247.466865030563 -1.7613549658847 0.0791363034090053 EML4 other 0.273805553754961 1 0.885584830470797 3.98180167468501 -1.7613549658847 0.135604099481888 381.778148963458 245.836970539821 1.55297288331015 0.121418030777891 -915.010520044031 894.913622410921 -1.02245680156144 0.30733707850578 CALM2 other 1 1 1 1.55297288331015 -1.02245680156144 0.0242889800162009 14.2234729957971 6.14381763634399 2.31508710669692 0.0212424720544809 -27.7356628798167 24.3242660474039 -1.1402466502284 0.255038931606729 CHAC2 other 1 1 1 2.31508710669692 -1.1402466502284 0.969476860081094 19.7502839584399 186.927847177251 0.105657258972827 0.915920492413151 -154.602641930452 740.1978183128 -0.208866654434151 0.834685226723842 RPS27A essential 1 1 1 0.105657258972827 -0.208866654434151 0.0345690412201203 13.0300434038615 5.00424506281627 2.60379802353814 0.00965084203828771 5.81257022832927 21.4268972375039 0.271274471702577 0.786355398460794 WDPCP other 1 1 1 2.60379802353814 0.271274471702577 4.61374115936632e-05 95.1371583060832 21.4757570090568 4.42997926759749 1.29691151103083e-05 105.611020674971 88.4664569911968 1.19379733592677 0.233444255996807 VPS54 other 0.413529620114003 1 0.144398127638173 4.42997926759749 1.19379733592677 7.15616655146102e-06 231.101942552445 50.5866456946427 4.56843776413742 7.03859220427797e-06 -206.388941577519 173.172320895549 -1.19181252818113 0.234223438953085 ASXL2 other 0.0691929743860766 1 0.0798809829263507 4.56843776413742 -1.19181252818113 0.00765994232403796 30.8798101093921 11.3645649806275 2.71720124457304 0.00694310980861641 77.930700907846 49.0080380672118 1.59016161391665 0.112788894647329 ETAA1 other 1 1 1 2.71720124457304 1.59016161391665 0.438594347620974 28.5735820147656 22.9386455915751 1.24565253430918 0.213803258020448 31.5375614390273 98.6313539623006 0.319751885907211 0.749365081191425 SNRPG essential 1 1 1 1.24565253430918 0.319751885907211 0.00290044086652661 2.95110113901075 1.51713364087867 1.94518205878131 0.0526286608514283 16.3263687422291 5.27830565874892 3.09310786410555 0.00215522801212411 ABHD1 other 1 1 1 1.94518205878131 3.09310786410555 0.0593595089292898 -54.6261836752233 30.8246315150893 -1.77216015213296 0.0773224329474786 214.652790057784 132.392060316753 1.62134186554858 0.105932295841813 MEIS1 other 1 1 1 -1.77216015213296 1.62134186554858 9.67187063703401e-13 193.401343678468 27.6767812196293 6.98785534863068 1.76026023815655e-11 -218.068670293408 91.9599810358241 -2.37134314119157 0.0183445222623168 CIAO1 essential 1.27494598737382e-08 1 2.42387834794157e-07 6.98785534863068 -2.37134314119157 0.00156884322847723 33.5752406788453 10.385107487725 3.23301811931467 0.00136045785613806 -43.4762682417409 35.5455133201215 -1.22311549843704 0.222239630233793 ZNF514 other 1 1 1 3.23301811931467 -1.22311549843704 9.55748869005615e-10 1332.58589137608 212.88147366166 6.25975510435447 1.30594650309894e-09 -959.278961919196 707.328504910108 -1.35620006158398 0.176038653417893 SNRNP200 essential 1.15626498172299e-05 1 1.73272982031168e-05 6.25975510435447 -1.35620006158398 2.73825706493965e-07 186.982561422754 35.7382560287424 5.23200016454003 3.14200265201341e-07 -171.817735254622 122.322725807999 -1.4046264430398 0.161160060980076 MRPS5 essential 0.00294910285894 1 0.00383135803386516 5.23200016454003 -1.4046264430398 0.145083095805958 30.1580179869099 15.4978045015741 1.94595421460161 0.0525354165744113 -12.3414311051119 64.1297655349126 -0.192444662820313 0.847515981270607 TPRKB other 1 1 1 1.94595421460161 -0.192444662820313 3.17998678038819e-05 335.317843171144 72.4973568440588 4.62524232286716 5.43941585602392e-06 105.609348143726 299.857795654392 0.35219810748375 0.724921529881241 EXOC6B other 0.289696795693364 1 0.0621616444026413 4.62524232286716 0.35219810748375 0.415040533461948 5.62836651007865 16.1396846624703 0.348728406272171 0.727522548386719 -83.9295605586891 66.7556787739902 -1.25726473163195 0.209574614774322 SFXN5 other 1 1 1 0.348728406272171 -1.25726473163195 3.33656194308202e-06 264.849408015567 51.7227203623148 5.1205622241118 5.27065185611571e-07 36.5936386228918 214.75212774127 0.170399422849859 0.864803709673116 TEX261 other 0.033152079466463 1 0.00636378505107411 5.1205622241118 0.170399422849859 0.126607783112228 9.16091849387092 8.65540843083461 1.05840395252007 0.290669603880611 -60.0051904634845 35.8159965962889 -1.67537402741718 0.0948376929450176 DQX1 other 1 1 1 1.05840395252007 -1.67537402741718 0.010400907478215 81.1211479603847 27.0933824115525 2.9941314350546 0.00296680252121906 -40.5541632006026 112.112155074876 -0.361728513500769 0.717793651463964 DUSP11 other 1 1 1 2.9941314350546 -0.361728513500769 0.0169582369575011 59.1894351517619 20.83305076942 2.84113142174279 0.00478453599088797 55.130306573796 65.8492805906503 0.83721957292915 0.403095934196847 ST6GAL2 other 1 1 1 2.84113142174279 0.83721957292915 0.343953822153415 0.374526247741826 6.41642343034498 0.0583699395477223 0.953490390943939 -30.6572431539885 21.3454089495126 -1.43624529408177 0.151909422436275 NPHP1 other 1 1 1 0.0583699395477223 -1.43624529408177 0.248612676315219 289.203988177098 185.419440367202 1.55972851392692 0.119815551041459 -215.71013164499 603.098551586536 -0.357669788921784 0.720826973489296 MALL other 1 1 1 1.55972851392692 -0.357669788921784 0.0847646067889303 59.5551120114392 30.0414560928294 1.98243093901345 0.0482968623408475 144.799362488084 122.375558007738 1.18323760761874 0.237604394818875 THNSL2 other 1 1 1 1.98243093901345 1.18323760761874 1.16764142369724e-05 449.367181592763 99.5823589556616 4.5125179429907 9.05739995321642e-06 -347.737022830215 316.438116096424 -1.09891004004161 0.27264649892421 RALB other 0.110739112623446 1 0.102031610472983 4.5125179429907 -1.09891004004161 7.11129840328917e-06 43.9607402357675 8.92601155589445 4.92501493645695 1.36426952854755e-06 3.69129158395282 28.3637615198467 0.130141116204561 0.896537847040269 TMEM177 other 0.0687804781566129 1 0.0161597725656457 4.92501493645695 0.130141116204561 0.0979785648839959 1.84813449900806 2.04918778288837 0.901886354408711 0.367795558415101 -12.0757917498492 6.69107529495161 -1.80476100141338 0.0720520658974649 NT5DC4 other 1 1 1 0.901886354408711 -1.80476100141338 0.682451564312194 10.5503383317093 12.8185481456053 0.823052518262482 0.411091052772563 -6.91861342588137 41.8428330664666 -0.165347633485794 0.868774776181121 RABL2A other 1 1 1 0.823052518262482 -0.165347633485794 0.0338553768863982 191.881860709051 76.2444780967697 2.51666567204401 0.0123357226879344 271.752415871781 248.955975645481 1.0915681584553 0.27584413029337 SLC20A1 other 1 1 1 2.51666567204401 1.0915681584553 0.26942728630504 21.5432055473116 14.8480004398234 1.45091627890386 0.147782719975603 -24.5079384620973 49.2226308469858 -0.497899808287027 0.618896650912693 FBLN7 other 1 1 1 1.45091627890386 -0.497899808287027 0.0105387327124344 32.4341369626698 11.9618250184393 2.71147060859627 0.00706031693533711 -36.6561098065765 38.9160371798062 -0.941928121746108 0.346939979786028 ZC3H8 essential 1 1 1 2.71147060859627 -0.941928121746108 0.000303737697927002 7.69181874931838 2.99949637439596 2.56437007724917 0.0107967084958387 -24.9502489479878 9.43390431174622 -2.64474263502144 0.00858240319108643 LIPT1 other 1 1 1 2.56437007724917 -2.64474263502144 0.000160400395206984 51.0659556928394 13.287598193105 3.84312913069105 0.000147830537868565 -51.4743498189871 44.1678233568637 -1.16542645543315 0.244757025706529 FAHD2B other 1 1 1 3.84312913069105 -1.16542645543315 0.716908117281456 7.18875015807133 9.9312545117579 0.723851165989187 0.46968926237865 -7.4435332098518 31.3541622649305 -0.237401756964732 0.812498000148535 AFF3 og 1 1 1 0.723851165989187 -0.237401756964732 0.000161192236970112 311.879354608165 112.337159395135 2.77627951683521 0.00582855953167402 -777.205101421266 289.631630619621 -2.68342618435203 0.00767344650012358 UBXN4 other 1 1 1 2.77627951683521 -2.68342618435203 0.0398859301394217 52.1422813394247 30.0514312978209 1.73510142737213 0.0837040156707521 -117.445829009195 76.9320698100054 -1.52661730406115 0.127862826851305 SPOPL other 1 1 1 1.73510142737213 -1.52661730406115 0.618653800120002 7.18788792941588 12.5515704973684 0.572668410771615 0.567280357363383 -21.8145207870262 32.121754740272 -0.679119835246009 0.497563799520781 THSD7B other 1 1 1 0.572668410771615 -0.679119835246009 3.35322057663968e-05 127.112781837851 34.860222263524 3.64635603516664 0.000310648268055325 -217.071246507428 98.0731027803864 -2.21336166954474 0.0275822736992548 POLR2D essential 0.304640089387715 1 1 3.64635603516664 -2.21336166954474 5.12544861035693e-11 152.075795605782 23.2434831411028 6.5427283287356 2.41459319880482e-10 -118.128289243269 65.3914508587849 -1.80647909920781 0.0717887770428539 AMMECR1L other 6.4734415948808e-07 1 3.25583746926842e-06 6.5427283287356 -1.80647909920781 0.342525432531664 9.39531936280405 8.14527879670682 1.15346811291501 0.249581804047126 -14.4873505889037 21.0741838011612 -0.687445394117963 0.492301596235096 GALNT13 other 1 1 1 1.15346811291501 -0.687445394117963 3.08480732066779e-05 303.444927410083 74.0979376639849 4.09518722081211 5.34832047440275e-05 -278.877130411196 194.520017874852 -1.43366802788707 0.152643381403395 PKP4 other 0.281612060303762 1 0.569007815271709 4.09518722081211 -1.43366802788707 7.48471672236047e-08 66.4350563055191 12.2156348244939 5.4385267126935 1.0887971654533e-07 -70.9306672728541 45.7407971024389 -1.55070903364454 0.121988422357705 SCRN3 other 0.000831028097683683 1 0.00135402815495773 5.4385267126935 -1.55070903364454 2.00517372960189e-10 209.720058972592 31.9457444410768 6.56488251070237 2.18097537952184e-10 -161.022510445895 118.923284859472 -1.35400321842918 0.176718411995156 LNPK other 2.48801956369002e-06 1 2.94388056727858e-06 6.56488251070237 -1.35400321842918 0.342668833081689 6.53835637414869 4.47552817084046 1.46091279611382 0.145032954745775 0.678274079169746 13.1152613455713 0.0517163982705373 0.958787346702895 ZNF385B other 1 1 1 1.46091279611382 0.0517163982705373 0.01661825276707 100.636309832663 37.6624442804987 2.67205997261234 0.00793471073775234 -104.355841296608 141.332250334921 -0.738372459571768 0.46084318170839 CDCA7 other 1 1 1 2.67205997261234 -0.738372459571768 0.0145452993006213 15.9410614202041 5.72198183926594 2.78593359224103 0.00566189360770969 -11.4779611247227 21.1810035701277 -0.541898833391938 0.588272524484178 DLX1 other 1 1 1 2.78593359224103 -0.541898833391938 8.31474711533853e-13 321.972768523626 45.4112012923832 7.09016188430212 8.66339418938558e-12 -316.677063419328 140.517864641565 -2.25364272526566 0.024897277633305 UBR3 other 1.09729717681123e-08 1 1.1998800952299e-07 7.09016188430212 -2.25364272526566 0.0586876624721857 2.49384069502896 1.99160629254101 1.25217554512101 0.211428965366016 -10.8473485518266 5.92455052423148 -1.83091502173216 0.0680517796508712 PHOSPHO2 other 1 1 1 1.25217554512101 -1.83091502173216 0.0133746604499569 40.9101986539726 14.6484869783439 2.79279346149903 0.00554507218457027 -22.6471819039391 46.751023220798 -0.484421095918691 0.628423695962519 GULP1 other 1 1 1 2.79279346149903 -0.484421095918691 7.74144683107349e-05 55.0355700860587 12.4605619542965 4.41678074294893 1.3764047580663e-05 22.9817780644782 41.6849431635097 0.551320844419335 0.581802136236348 FAM171B other 0.67511995936641 1 0.152959860763908 4.41678074294893 0.551320844419335 4.61988997850696e-08 1665.6742281958 289.331198546215 5.7569810534267 2.03266957081239e-08 -135.992399342646 706.682130116394 -0.19243786356993 0.847523239064813 HSPD1 essential 0.000518397854488266 1 0.000260181705063986 5.7569810534267 -0.19243786356993 0.236253537178165 2.85797317026138 4.46263414454422 0.640422915635017 0.522358876672607 -15.4453975665136 11.1810969083085 -1.38138482236357 0.168130494634064 CCDC150 other 1 1 1 0.640422915635017 -1.38138482236357 3.34823730695611e-08 34.5498726136879 11.5057405650163 3.00283779374778 0.00288824106692867 -75.5634663037032 21.6546712178862 -3.48947649878377 0.000552705170633831 METTL21A other 0.000378786086535945 1 1 3.00283779374778 -3.48947649878377 0.339188630691904 10.1200495610996 11.7872560686897 0.858558556980982 0.391232822227675 -15.9767609339222 22.1733447130704 -0.720539058976723 0.471724145854455 PTH2R other 1 1 1 0.858558556980982 -0.720539058976723 0.586910361729578 261.848165003448 271.747706085519 0.963570838463834 0.335997916083408 410.408132009774 597.999986877866 0.686301239156372 0.49302642214826 NBEAL1 other 1 1 1 0.963570838463834 0.686301239156372 6.79346270539884e-06 28.4299904878932 11.864190791731 2.39628567906276 0.0171395328394825 -63.6927842726031 22.140823542363 -2.8767125193305 0.00428994988233634 KANSL1L other 0.0658354470780202 1 1 2.39628567906276 -2.8767125193305 0.0238629395510463 8.28739839494083 14.6435038128055 0.565943677202011 0.57182871080818 -54.7667983348757 25.7506570430606 -2.12681168652489 0.0342005082308339 SPAG16 other 1 1 1 0.565943677202011 -2.12681168652489 0.0217892385216809 338.816743239993 150.830151533535 2.24634623644637 0.0253635440723085 -115.895643067577 265.113721570994 -0.437154449723726 0.662294202364186 ABCA12 other 1 1 1 2.24634623644637 -0.437154449723726 8.22703720714713e-17 262.556420737198 33.5243242706662 7.83181843181653 7.41432554417184e-14 -40.7332830089546 55.6037615730995 -0.732563442770046 0.464369471425802 SUMF1 other 1.15688597206903e-12 1 1.05668967655537e-09 7.83181843181653 -0.732563442770046 2.81807664272664e-15 49.6992098892182 20.0526247503361 2.47843913243253 0.0137111158414806 -217.779143295156 34.7578829005827 -6.26560437866903 1.19782622835706e-09 RHBDD1 other 3.89007299761986e-11 1.82716412873586e-05 1 2.47843913243253 -6.26560437866903 0.0452855956428333 677.890666928516 319.599209446619 2.12106490533025 0.0346873772565148 -130.334208491555 571.361417839715 -0.228111672265764 0.819705573289975 ACKR3 other 1 1 1 2.12106490533025 -0.228111672265764 0.413159099589381 -29.2450472399561 28.028015113355 -1.04342198766766 0.297545449833789 -61.1141176646334 50.7298220886492 -1.20469804837553 0.229215696186358 HES6 other 1 1 1 -1.04342198766766 -1.20469804837553 0.0294077050991622 21.7317389763249 10.4322120215963 2.08313816200599 0.0380371781134137 -10.7775326035143 18.8819742570525 -0.570784201736152 0.568549048348456 ESPNL other 1 1 1 2.08313816200599 -0.570784201736152 0.00358022237159229 -3.01473455685773 12.7538767781292 -0.236377895858889 0.813290677104002 -71.9840535213443 23.0981231967502 -3.11644599468896 0.001996376720419 ANKMY1 other 1 1 1 -0.236377895858889 -3.11644599468896 2.2276704354712e-10 49.6669879273181 29.2952998948697 1.69539100489004 0.0909800937552504 -261.746766150194 50.547416240624 -5.17824224494847 3.98145512635434e-07 COPS7B other 2.76075197067946e-06 0.00599248811067592 1 1.69539100489004 -5.17824224494847 5.53066169970204e-10 43.0172551643676 20.5252785215678 2.09581834025616 0.0368910620022168 -168.999088943792 35.4132973529668 -4.77219297766503 2.7861123314252e-06 DIS3L2 other 6.75736246469595e-06 0.0414726151693449 1 2.09581834025616 -4.77219297766503 1.57840152069558e-22 225.688644470095 31.1755621249167 7.23928067650513 3.37340233800616e-12 -226.288322933661 54.466905553825 -4.15460215029179 4.18594206935208e-05 FANCD2 other 2.32766872256977e-18 0.605412801490391 4.70049881777778e-08 7.23928067650513 -4.15460215029179 7.14897247046573e-26 39.9128896131746 6.4319076099562 6.20545132697364 1.69283116605015e-09 -61.6797684192467 10.3522551575943 -5.95809970680632 6.74562950283282e-09 TAMM41 essential 1.06920032268285e-21 0.000102601024738087 2.23826136775151e-05 6.20545132697364 -5.95809970680632 7.75498294305869e-08 519.487208165369 113.509841165916 4.57658298901185 6.77908017666749e-06 -200.328968179088 182.695851667491 -1.09651623915189 0.273679996125896 VGLL4 other 0.000860725556850084 1 0.0770171298871194 4.57658298901185 -1.09651623915189 4.17870249041419e-19 266.224476602282 47.7812046663138 5.57174057166399 5.35630957055135e-08 -326.991824423824 73.1141114128924 -4.47234901860771 1.07599002239888e-05 RAB5A other 6.02025667793973e-15 0.158245852594203 0.000674037996358182 5.57174057166399 -4.47234901860771 1.39625792114349e-18 313.629622535921 70.6277340958739 4.44060150804475 1.23686780915099e-05 -690.925426529078 123.969746954071 -5.57333900814571 5.31169130940822e-08 RETREG2 other 2.0016753557513e-14 0.000804030713505123 0.137886023364152 4.44060150804475 -5.57333900814571 5.6249836780751e-14 235.097297789988 87.7167129135618 2.68018818741713 0.00773900249620271 -871.191323223995 153.899356755039 -5.66078599412644 3.35175916198879e-08 CTDSP1 other 7.59372796540138e-10 0.000507925583407782 1 2.68018818741713 -5.66078599412644 1.08826073246356e-13 83.1559949762751 56.8626025923714 1.46240219731749 0.144612424544634 -639.865479440409 99.7656851437989 -6.41368300651801 5.10066407737689e-10 CNOT9 other 1.46186064191831e-09 7.79381471023189e-06 1 1.46240219731749 -6.41368300651801 1.10700764478588e-14 76.2861752234284 23.5899627246053 3.23384043094985 0.00134884817559792 -222.770901276955 41.4252025265793 -5.37766595429485 1.45871078248015e-07 STK11IP other 1.51482926112499e-10 0.00220250741046677 1 3.23384043094985 -5.37766595429485 1.93969311251155e-12 184.380029401226 41.2658842205746 4.46809835494319 1.09848336371761e-05 -249.612231157891 72.5142102125348 -3.44225263470832 0.000654058697060433 GMPPA other 2.5375065297876e-08 1 0.12284339456454 4.46809835494319 -3.44225263470832 0.000944798022525945 4.72714984132436 7.4994944801531 0.63032913136138 0.528930535620051 -36.0591954713096 12.070552800127 -2.98736901850347 0.00303207500217596 GRIP2 other 1 1 1 0.63032913136138 -2.98736901850347 5.11303920873968e-17 228.882209837884 35.8362522547694 6.3868902420571 5.95910638332315e-10 -161.270864416295 57.732592709078 -2.79341108460102 0.00552969754529132 EAF1 other 7.20682876471858e-13 1 7.97566798343971e-06 6.3868902420571 -2.79341108460102 0.00325998671105788 27.7653924889785 9.69087395531196 2.86510717371978 0.00444977159123304 -4.72582671067689 15.6139357234396 -0.302667232297011 0.762343874794949 CNTN4 other 1 1 1 2.86510717371978 -0.302667232297011 1.07529276354577e-17 178.123496430406 31.741484955787 5.61169386619799 4.34332607822407e-08 -175.823486687098 47.2381448317129 -3.72206587099206 0.000233386562889955 DYNC1LI1 other 1.52874372193302e-13 1 0.000548475217158135 5.61169386619799 -3.72206587099206 0.288742681436074 33.3111670616122 24.3304751562061 1.36911288611292 0.171930203865572 0.212804286945235 36.1809104810258 0.00588167307334166 0.995310818912272 RBMS3 other 1 1 1 1.36911288611292 0.00588167307334166 1.10642811933141e-09 153.859125050931 35.4803054491783 4.33646562798951 1.94262048264017e-05 -114.693337348757 52.8023124884121 -2.17212716533821 0.0305799740745682 OSBPL10 other 1.33424166910174e-05 1 0.213688253090418 4.33646562798951 -2.17212716533821 6.23174233697273e-07 94.2482808764451 29.0093181777829 3.24889679581046 0.00128162101751653 -85.2066748001544 41.5712224849881 -2.04965525925834 0.0412128925447223 POMGNT2 other 0.00654582215075615 1 1 3.24889679581046 -2.04965525925834 0.066025543967778 17.4588318689648 12.6245815988882 1.38292360283071 0.16765249330457 -15.9989959490681 18.0043049690371 -0.888620581387746 0.374874498043181 ACKR2 other 1 1 1 1.38292360283071 -0.888620581387746 0.444556934224616 15.8505410001725 15.3434753161497 1.03304764230885 0.302361697496867 -2.12791141892399 21.9876600391485 -0.0967775295386274 0.922963651606863 FAM198A other 1 1 1 1.03304764230885 -0.0967775295386274 0.000245289688045671 328.142539431861 100.868399340342 3.25317484542079 0.00126309419757485 -60.975363332867 144.487904942411 -0.422010156193835 0.673300980242808 CSRNP1 other 1 1 1 3.25317484542079 -0.422010156193835 1.63142279139287e-12 71.9376536793082 30.3157535859858 2.37294624642163 0.0182373654358725 -214.003602342922 43.4254905504146 -4.92806413077764 1.3350412928472e-06 SLC25A38 other 2.1394478486326e-08 0.0199708826997013 1 2.37294624642163 -4.92806413077764 0.773154045345486 -21.5227195490074 41.9372892513171 -0.513211987070228 0.608157166610377 -41.9227235471683 60.0726402174922 -0.697867172066811 0.485767031944843 ITGA9 other 1 1 1 -0.513211987070228 -0.697867172066811 3.08228468216729e-08 507.902619794893 124.52298542753 4.07878608155023 5.71975269395467e-05 -285.773442216584 178.371674372375 -1.60212344937679 0.110114938339098 GOLGA4 other 0.000349531082957771 1 0.606465378140014 4.07878608155023 -1.60212344937679 3.92630638014294e-24 143.269575995043 51.4007875270644 2.787303130708 0.00563245028922738 -574.428792755332 73.6285313412842 -7.80171466537517 8.72378117520776e-14 CTDSPL other 5.83135023578829e-20 1.33805355665337e-09 1 2.787303130708 -7.80171466537517 0.0293652159011818 36.5038282939279 17.2234309778929 2.11942837294046 0.034823994178579 -8.66451029740173 25.6647044275887 -0.337604133406176 0.735882876084263 STAC other 1 1 1 2.11942837294046 -0.337604133406176 8.4882151050711e-06 142.868107041771 53.0548904190693 2.69283577655682 0.0074590159404902 -202.478406381336 85.3926698396946 -2.37114504982035 0.0183267681826597 IQSEC1 other 0.0815462825144181 1 1 2.69283577655682 -2.37114504982035 0.367457484284397 36.7622609143153 30.3165767596511 1.21261253227122 0.226175253934379 -3.78236555450737 48.795000978386 -0.0775154314718179 0.938262111940497 CAND2 other 1 1 1 1.21261253227122 -0.0775154314718179 5.17287570222074e-15 2458.94637962091 626.750531049687 3.92332556224986 0.000106988283447608 -4901.5107264774 1008.76471041664 -4.85892366759435 1.85382569212637e-06 RPL32 essential 7.11322137812374e-11 0.027681325234831 1 3.92332556224986 -4.85892366759435 0.000498568336162675 205.805305419814 67.2795194530734 3.05895920620183 0.0024087200178737 -43.8770426145057 97.1113368654333 -0.451822042933112 0.651703275331994 PTPRG other 1 1 1 3.05895920620183 -0.451822042933112 0.292040933082806 43.7880687344645 55.4999247214848 0.788975281573914 0.430710598382362 -57.6650148441525 80.588734307182 -0.715546848326832 0.474792973361901 IL17RD other 1 1 1 0.788975281573914 -0.715546848326832 4.16233188404247e-19 63.5284767137725 17.834947184997 3.56202213860288 0.000424320378583575 -143.772948867848 24.918288169973 -5.76977631397236 1.88333831778271e-08 SHQ1 essential 5.99708777852839e-15 0.000285758922957171 1 3.56202213860288 -5.76977631397236 4.68808829170906e-06 108.716893914707 42.3483147547079 2.5672070906345 0.0107091352284206 -135.214769023634 59.3148747821075 -2.27960978625251 0.0232928775543904 SLC25A26 essential 0.0460745317309167 1 1 2.5672070906345 -2.27960978625251 6.21020368533779e-25 74.4457240513194 45.0181029729214 1.6536841655922 0.0991784645961659 -545.544693907803 62.5263530129078 -8.72503620665645 1.51994420383195e-16 UBA3 essential 9.25382451152184e-21 2.33448230266549e-12 1 1.6536841655922 -8.72503620665645 4.95309222465871e-07 34.8553754583616 129.137480559725 0.269909055893663 0.787405289120134 -804.704660679172 179.36108284109 -4.48650648140947 1.01294728518851e-05 ARL6IP5 other 0.00523888564602152 0.149095710906897 1 0.269909055893663 -4.48650648140947 1.97888677113468e-09 140.805700332566 46.7965829956451 3.00888849824078 0.00283157315812127 -211.446615742203 64.9965119575021 -3.25319943138576 0.00126377782331361 TMF1 other 2.36476969150595e-05 1 1 3.00888849824078 -3.25319943138576 0.186575974827843 220.882366594962 160.680894599629 1.37466477981304 0.170203271699217 -64.2635429685457 225.056586035563 -0.285543934085941 0.775413350086222 LRIG1 other 1 1 1 1.37466477981304 -0.285543934085941 5.00066274846283e-07 93.831569023735 41.6408601545709 2.25335328510103 0.0249135848965251 -185.525528060534 59.6726007603203 -3.10905718364298 0.00204546102005397 LIMD1 other 0.00528620059140006 1 1 2.25335328510103 -3.10905718364298 0.0826557978951066 5.07007122963546 2.29920224740674 2.20514364726025 0.0281549031824245 2.66656807893589 3.29482573768768 0.809319912866558 0.418932506361217 ZNF660 other 1 1 1 2.20514364726025 0.809319912866558 0.0110977546810858 169.753132749261 76.7197322390481 2.21263979676486 0.0276303202489014 -440.457790034065 313.506495644245 -1.40493991720631 0.161012169331556 NFKBIZ other 1 1 1 2.21263979676486 -1.40493991720631 0.824842744675798 -8.59764722657912 83.3081538034471 -0.103202949940098 0.91786715584545 195.306688418987 347.257668168168 0.562425847784029 0.574223409821071 COL8A1 other 1 1 1 -0.103202949940098 0.562425847784029 0.000398223977501126 103.514094139079 26.7270405521722 3.87300995547994 0.000130445159065235 3.159714898985 109.217023807448 0.0289306079659858 0.976938024998335 NXPE3 other 1 1 1 3.87300995547994 0.0289306079659858 0.539972622417575 22.5993343823108 22.5413474971903 1.00257246755669 0.316831856228584 -18.4075290366659 92.0562117118453 -0.199959662627496 0.841640341052949 ADGRG7 other 1 1 1 1.00257246755669 -0.199959662627496 0.449386445375212 10.5519903870284 9.77498004996909 1.07948971078072 0.281190126934193 -16.1889447341271 39.4840465267589 -0.410012300111024 0.682073873490103 MYH15 other 1 1 1 1.07948971078072 -0.410012300111024 2.29671812956532e-05 481.11901759378 105.422028439016 4.56374274634732 7.17257129565911e-06 -14.6499296557346 431.222903980817 -0.0339729859441471 0.972919873219721 PHLDB2 other 0.212101919265357 1 0.0813297859214787 4.56374274634732 -0.0339729859441471 3.01200879739341e-12 124.519059234455 17.088404649391 7.28675741178056 2.49555525959546e-12 -30.2228101216816 69.6679169073867 -0.433812455765807 0.664716953137713 ABHD10 other 3.92284025772518e-08 1 3.48529247555102e-08 7.28675741178056 -0.433812455765807 0.412898278058477 5.93779949194619 7.62516485542272 0.778710966192877 0.436725436919906 -27.2047395714825 31.0871238393601 -0.875112786633478 0.382168893468301 TAGLN3 other 1 1 1 0.778710966192877 -0.875112786633478 0.471570019908728 -1.34558691813598 3.79862166391196 -0.354230306987257 0.723401060751918 16.3605317706067 14.9436106270068 1.09481785754235 0.274424971388535 PLA1A other 1 1 1 -0.354230306987257 1.09481785754235 3.01126385074003e-15 121.422869812666 14.5973617886831 8.31813800126551 2.63002312103942e-15 -44.4704020411574 57.5212631587315 -0.773112403989463 0.440028339589252 RABL3 other 4.15275868630246e-11 1 3.79827939140513e-11 8.31813800126551 -0.773112403989463 0.00278340743666525 24.0422968327492 7.16138951891425 3.35721116261726 0.000882873762345439 -6.87637939907801 28.172591531206 -0.244080470604248 0.807325896450169 ADPRH other 1 1 1 3.35721116261726 -0.244080470604248 0.000297314323125339 35.0833745301744 9.13411466478716 3.8409168066856 0.000147866948663197 74.523178675546 35.7643251563853 2.08372948041607 0.0379804355667833 IGSF11 other 1 1 1 3.8409168066856 2.08372948041607 1.16821711214782e-22 318.9695069942 30.5868225585631 10.4283309056861 4.11483099641832e-22 -89.1357547113013 125.649047568029 -0.709402549693357 0.478591258561121 ATG3 other 1.72393799239654e-18 1 6.15743310304037e-18 10.4283309056861 -0.709402549693357 0.617135084250575 34.5147205163198 42.2424990263066 0.817061521261459 0.414501151202444 -60.1869393100127 173.529949356013 -0.346838914742801 0.7289403120763 BOC other 1 1 1 0.817061521261459 -0.346838914742801 7.81283840013896e-10 412.383116572836 61.6028038262944 6.69422641436355 9.72792983488793e-11 209.760050000334 252.166064277477 0.831832985145534 0.406123524999672 SRPRB essential 9.48947352080879e-06 1 1.32192838526292e-06 6.69422641436355 0.831832985145534 0.0449515709067789 21.7384555996362 8.91180106502156 2.43928869608173 0.0152591585059018 -8.04341237263133 36.5498941384107 -0.220066639377169 0.825959579449219 TMEM108 other 1 1 1 2.43928869608173 -0.220066639377169 1.67967683236744e-10 37.6055884199958 5.46552546605483 6.88050740108262 3.19384240577332e-11 -21.7609435648438 34.118333228818 -0.637807932143162 0.524059145741781 MED12L other 2.08733439958302e-06 1 4.37907732255581e-07 6.88050740108262 -0.637807932143162 1.07209570866248e-25 505.964457725438 43.0269385840661 11.7592483773133 9.43365362376085e-27 71.9226577605912 261.088752623886 0.27547206472046 0.783132495839386 EIF2A other 1.60267587487954e-21 1 1.42589674523145e-22 11.7592483773133 0.27547206472046 0.933210554977717 7.88641470944947 37.7428704376251 0.208951110978238 0.834619350580092 -39.5987529547937 150.611173327781 -0.262920420044889 0.792781114338706 ALDH1L1 other 1 1 1 0.208951110978238 -0.262920420044889 2.75972136308027e-19 188.254307634605 19.1507181415754 9.83014350913102 4.22286863805851e-20 53.9756136695102 76.5818579240877 0.704809404376347 0.481441509513895 OSBPL11 other 3.9811740383796e-15 1 6.27560508301875e-16 9.83014350913102 0.704809404376347 0.000101530306830211 17.9232276256005 4.19496061424456 4.27256159801352 2.55613216946659e-05 -8.34316758474535 21.4879998463025 -0.388271018448512 0.698075283263769 TRPC1 other 0.874175941808116 1 0.278822897045415 4.27256159801352 -0.388271018448512 6.12527168524703e-10 181.861359024937 27.0842662466256 6.7146496555946 8.79739830394484e-11 -147.330227806626 195.552964053453 -0.753403194473461 0.45177039817613 NCEH1 other 7.46670618431613e-06 1 1.19635819535346e-06 6.7146496555946 -0.753403194473461 1.01818607971106e-18 579.358957531806 59.6780623556328 9.70807252553371 1.13793101644729e-19 162.543212822714 377.946640049519 0.430069209773679 0.667438433739668 LPP other 1.46119884299334e-14 1 1.68629997327324e-15 9.70807252553371 0.430069209773679 1.74395545098225e-12 162.016469635836 21.1065576744534 7.67612000662403 2.00444307503438e-13 34.6271394978282 131.896571650966 0.262532521235358 0.793079848827186 TMEM44 other 2.28458164078675e-08 1 2.83929361578619e-09 7.67612000662403 0.262532521235358 0.00537739010930712 19.3038519484508 12.1154682666681 1.59332281044054 0.112078117709783 -26.593443520408 17.1087506027627 -1.55437671270477 0.121086102413049 AMT other 1 1 1 1.59332281044054 -1.55437671270477 0.156428036236783 6.48597941057998 28.9109818218165 0.22434310431082 0.822633960669053 -61.359586030706 40.8263854754408 -1.50293946711538 0.133843946605686 TCTA other 1 1 1 0.22434310431082 -1.50293946711538 1.44515871180068e-10 21.0763819190533 15.6025529444937 1.35082905945154 0.177707578834708 -111.676563400592 22.0330061717998 -5.06860310072113 6.80288349491858e-07 NICN1 other 1.79821098509359e-06 0.0102097675491738 1 1.35082905945154 -5.06860310072113 0.0247619309136981 52.983698100416 30.5356259595683 1.73514367023524 0.0836841813667588 -36.8314080291873 42.9148953013111 -0.858242989306841 0.391404711206914 UCN2 other 1 1 1 1.73514367023524 -0.858242989306841 8.00252724080071e-15 214.321288098411 53.6360779878427 3.9958419060206 8.01091102556825e-05 -319.305578625714 76.1113799084743 -4.19524096146577 3.53696922210621e-05 DCAF1 other 1.097386560531e-10 0.512966646282063 0.838742384376996 3.9958419060206 -4.19524096146577 7.87581778094214e-08 387.096591710414 97.8528951701686 3.95590330809572 9.39975025567546e-05 -215.762246337069 138.856515219643 -1.55385036125801 0.121211631439102 MANF other 0.00087390074097334 1 0.976916044072351 3.95590330809572 -1.55385036125801 0.00108246911048768 17.0517482636816 4.59768691672179 3.70876672825728 0.000245452912073284 4.12002923727128 18.0286645714631 0.228526590027789 0.8193828551815 EAF2 other 1 1 1 3.70876672825728 0.228526590027789 5.53734091105717e-05 81.4199771903781 18.1110622403921 4.49559369349366 9.71139938842687e-06 62.4276704606861 71.0179427349378 0.879040817806939 0.380038738424063 ILDR1 other 0.491439005856324 1 0.109156129125918 4.49559369349366 0.879040817806939 0.0880484590892225 29.9039796095697 17.0756653380084 1.75126292402833 0.0808587152330573 142.842222093494 104.810232609899 1.36286523306507 0.173883248101933 TM4SF19 other 1 1 1 1.75126292402833 1.36286523306507 0.0732194849166958 881.076166403859 389.800748727954 2.26032445878848 0.0244728372353105 998.302696410354 2391.67159691045 0.417407932468636 0.676659960730834 MUC4 other 1 1 1 2.26032445878848 0.417407932468636 0.0744889758542928 4.05611389124866 28.0011607587507 0.144855205332196 0.884916671346996 102.714601722249 52.0379364192331 1.97384079366157 0.0492624063178391 SLIT2 other 1 1 1 0.144855205332196 1.97384079366157 1.66590648255561e-27 381.37714613387 31.8148816849894 11.9873821914544 1.4255320249314e-27 389.518587806766 209.244752862765 1.86154530748131 0.0635896670655467 EIF2B5 essential 2.50385744328108e-23 1 2.15782782613866e-23 11.9873821914544 1.86154530748131 3.49389448994152e-21 166.48855241049 16.3851575341046 10.1609369372223 3.44015724508918e-21 201.875505320872 107.76429322567 1.87330607642109 0.061943244736515 ECE2 other 5.11121824933545e-17 1 5.13202657822404e-17 10.1609369372223 1.87330607642109 2.33442298610699e-05 6.30146707025207 2.82563387574313 2.23010741920512 0.026437945961677 74.0065972711721 18.5840408857936 3.98226616729766 8.46507435483245e-05 VWA5B2 other 0.215513930077398 1 1 2.23010741920512 3.98226616729766 6.73793709204023e-10 137.94834335016 33.6669706467806 4.09743854882147 5.31071114146048e-05 -139.1545805573 62.1065716799856 -2.24057739451981 0.0257457928574414 DGKQ other 8.19804805988535e-06 1 0.565272093897053 4.09743854882147 -2.24057739451981 1.0062846028713e-07 136.745639424842 35.9643835288646 3.80225172816021 0.000173065982571591 -200.011354481515 76.5406157401874 -2.61314012890152 0.00941468151775348 FIP1L1 essential 0.00111023380234791 1 1 3.80225172816021 -2.61314012890152 0.344310795950657 3.41866493512848 2.91151354339358 1.17418823034008 0.241200989132645 -0.498838449118052 5.37096510633972 -0.0928768739400743 0.926060047758562 SLC26A1 other 1 1 1 1.17418823034008 -0.0928768739400743 4.26531573643539e-11 120.479186633939 31.062556682979 3.87859852823887 0.000127542176857162 -159.824153809301 57.3766634247696 -2.78552540823252 0.00566267997340814 LYAR other 5.40244891176906e-07 1 1 3.87859852823887 -2.78552540823252 0.00478006443889638 31.3860134813944 18.5871472677818 1.68858690519968 0.0922789209824938 -79.5236995972451 40.0058321711885 -1.9878026597961 0.0476908057060245 CENPC essential 1 1 1 1.68858690519968 -1.9878026597961 0.0550468407895405 12.3664601402986 6.25221748233557 1.97793185781487 0.0488332325472789 29.2572871334523 13.4130679338633 2.18125243812326 0.0299257239041602 CORIN other 1 1 1 1.97793185781487 2.18125243812326 1.03348289534808e-13 331.388715323831 68.9559703350709 4.80580163999647 2.41250515150475e-06 -496.989669604171 146.527001017155 -3.39179582025285 0.000785000066514469 ATP10D other 1.38879431476874e-09 1 0.0281491101077574 4.80580163999647 -3.39179582025285 7.83777207630789e-07 174.137543295615 107.042572974464 1.62680640474848 0.104845863316448 -881.527984054041 230.385086745853 -3.8263239886985 0.000158795530902711 OCIAD2 other 0.00817871516162728 1 1 1.62680640474848 -3.8263239886985 0.599098073550629 -5.56917543170911 9.32540279211371 -0.597204813117439 0.550825655369004 -20.5285244138085 20.4836397541567 -1.00219124433892 0.317067046589358 SLC10A4 other 1 1 1 -0.597204813117439 -1.00219124433892 1.11395093082152e-06 92.9035345847198 24.6608063167314 3.76725454113348 0.000196433667370477 -82.8142244072707 45.6412076782536 -1.81446172483137 0.0705429553094612 SLC10A6 other 0.0114948596551473 1 1 3.76725454113348 -1.81446172483137 0.0585052375550948 95.8674556444123 75.0459637752903 1.27744985635027 0.202378251208179 -184.295655740107 140.841150674462 -1.30853557257626 0.19163962519468 SCD5 other 1 1 1 1.27744985635027 -1.30853557257626 0.0216814979076094 -209.213634277567 87.4064291496488 -2.39357260458921 0.0172663363795185 -375.78022966283 164.038429763437 -2.29080606419332 0.0226306343576099 PLAC8 other 1 1 1 -2.39357260458921 -2.29080606419332 1.69709570235331e-11 211.122182446565 36.0421399052036 5.85764838053038 1.17161715485754e-08 -106.157604944925 68.1014273734627 -1.55881615171977 0.120034523014607 ENOPH1 other 2.17058540330988e-07 1 0.000151021451261136 5.85764838053038 -1.55881615171977 0.0088551718555357 -0.259190075943244 6.12697375086676 -0.0423031151237718 0.96628344473532 -31.9124063223893 11.0661840649708 -2.88377693114699 0.00419561330783186 TRMT10A other 1 1 1 -0.0423031151237718 -2.88377693114699 4.29544196666919e-08 107.313320209974 20.2407645070438 5.30184125074075 2.14148285997947e-07 -13.916174540682 37.588824159336 -0.37022106575328 0.711462701041806 KLHL8 other 0.000482979494732283 1 0.00263188243491477 5.30184125074075 -0.37022106575328 0.56225847133417 -4.27334003941521 27.8539173652098 -0.153419714124402 0.878164000263177 -54.5045908728391 52.335352296959 -1.04144881959658 0.298453479205283 SNCA other 1 1 1 -0.153419714124402 -1.04144881959658 1.49518114644338e-10 338.912625377818 59.7082612694413 5.6761429352034 3.08966511393294e-08 -152.289324355543 110.223114909939 -1.38164598668778 0.168044268171492 PYURF other 1.85985582806092e-06 1 0.000392371111725286 5.6761429352034 -1.38164598668778 4.0165280001506e-07 91.4728127079837 20.3059025411968 4.50474006375255 9.33585267020274e-06 -47.1603429927729 36.8638452275741 -1.27931155042657 0.201717110865728 TBCK other 0.0042727824865602 1 0.105075021803132 4.50474006375255 -1.27931155042657 4.66714492818003e-09 436.668312611016 76.2245842027039 5.72870704613862 2.34673578535924e-08 -90.6359029011236 137.665719941565 -0.658376703652848 0.510772466557675 CAMK2D other 5.50256387032426e-05 1 0.000299466953569693 5.72870704613862 -0.658376703652848 8.58697177416454e-08 107.743487251192 30.9210876060321 3.48446628475558 0.000561856427271954 -168.860163349612 56.1807793385915 -3.00565718983573 0.00285963757038639 CISD2 other 0.000951694081730656 1 1 3.48446628475558 -3.00565718983573 0.974893590525439 -2.70122036266226 36.1127084985507 -0.0747997166363377 0.94042080496765 10.9407264771552 65.2132742032619 0.167768397014606 0.866871462081991 DDIT4L other 1 1 1 -0.0747997166363377 0.167768397014606 0.700275468280039 10.3537384130729 27.2750490190888 0.379604759127167 0.70449220335999 41.8311084921699 49.8325710586061 0.839433077674719 0.401856940505447 ANK2 other 1 1 1 0.379604759127167 0.839433077674719 0.013577100949371 -5.12357721375709 24.9540105677628 -0.205320792016337 0.8374528679394 -129.141321883248 45.5919439024638 -2.8325469552148 0.00491254986694181 TIFA other 1 1 1 -0.205320792016337 -2.8325469552148 0.0011223794265185 29.815384377413 12.7032715673734 2.3470634489142 0.0195331691479711 -43.282756925714 22.9208103908363 -1.88836067257981 0.0598847302074281 SPATA5 other 1 1 1 2.3470634489142 -1.88836067257981 0.0142404560942181 123.742269943008 68.25983976798 1.81281219474902 0.0708006517673267 -188.233256030853 123.162827491552 -1.52832847267789 0.127421937951465 CCNA2 essential 1 1 1 1.81281219474902 -1.52832847267789 2.51946608098498e-05 49.8070011227426 14.8040960242522 3.36440678587523 0.0008609474934309 -49.6863722716268 26.9292532114979 -1.84507055882309 0.0659569441025494 METTL14 essential 0.231841268772238 1 1 3.36440678587523 -1.84507055882309 1.67461160413932e-06 181.175147651648 46.6174713731007 3.8864215993532 0.000123905027254848 -152.135529951299 83.261998750853 -1.82719046184008 0.0686112128496762 USP53 other 0.0170308000140969 1 1 3.8864215993532 -1.82719046184008 0.000623946837640868 317.197016290732 102.752336547141 3.08700538547081 0.00220151529710926 -192.024276438995 181.587612239403 -1.0574745384384 0.291105348374765 SETD7 other 1 1 1 3.08700538547081 -1.0574745384384 1.46754581248405e-13 61.8480939286689 8.73146865738722 7.08335520122867 9.2350111073975e-12 -8.70239504492232 14.9500777237366 -0.582096976733795 0.560917735418062 NAF1 essential 1.96636463414738e-09 1 1.27831023748596e-07 7.08335520122867 -0.582096976733795 0.435359451557848 -1.98082709108241 13.5498670014077 -0.146187936079124 0.883866536755399 -28.4553773913118 23.2358048645723 -1.22463489244988 0.22162784688272 MARCH1 other 1 1 1 -0.146187936079124 -1.22463489244988 0.231830463799151 884.637151755767 525.841763614273 1.68232577358516 0.0934842054113987 913.487106373213 899.367141663882 1.01569988946139 0.310542052811735 SFRP2 other 1 1 1 1.68232577358516 1.01569988946139 0.00111776752759477 432.489133052669 212.006181300144 2.03998360047993 0.0421779373880282 -739.420240545747 365.519682722217 -2.02292865609561 0.0439169546246576 RPS3A essential 1 1 1 2.03998360047993 -2.02292865609561 0.157709542267842 6.76650343429116 4.4777631597714 1.5111347324222 0.131744065239082 -3.32495738596474 7.65848841364666 -0.43415321749916 0.664470675783458 RNF175 other 1 1 1 1.5111347324222 -0.43415321749916 2.60818948651269e-11 430.622696986219 62.7807583952585 6.85915092447723 3.62100834596755e-11 87.848096806731 107.626387346543 0.816231957353278 0.414978479549299 PDGFC other 3.32179013002256e-07 1 4.96114353481015e-07 6.85915092447723 0.816231957353278 3.50406511974637e-06 33.7824658945959 17.078990123741 1.97801308214564 0.0487874273008166 -101.008823753484 29.1540448382209 -3.46465899719895 0.000603508692607941 CBR4 other 0.034760325987884 1 1 1.97801308214564 -3.46465899719895 0.0259964705290074 -3.11633216064561 16.3080022411731 -0.191092208264342 0.848575682354993 -76.1682482333629 30.1661593057347 -2.52495677230223 0.0120587427679555 CYP4V2 other 1 1 1 -0.191092208264342 -2.52495677230223 1.53376141732036e-06 572.563138132292 111.163648347674 5.15063284304553 4.56214658504917e-07 -387.022353840837 652.081256344075 -0.593518599216755 0.553256053212639 NDUFS6 other 0.0156581703094236 1 0.00552430329983604 5.15063284304553 -0.593518599216755 9.82481745503938e-26 592.7499176384 51.3388589750483 11.5458334967376 5.45733103479374e-26 -359.618518936022 302.72291408801 -1.18794614546909 0.235741123340151 MARCH6 other 1.46900670587749e-21 1 8.23784119702115e-22 11.5458334967376 -1.18794614546909 0.0446637108295157 48.6979772177926 19.4690289462182 2.501304885432 0.0128744970050422 47.7716110471332 118.554296506442 0.402951326564006 0.687253950413979 NKD2 other 1 1 1 2.501304885432 0.402951326564006 8.29497335233419e-06 20.0997793173366 4.09871179980432 4.90392598920866 1.49917006087076e-06 23.9700147746701 23.47500545944 1.02108665389174 0.307987120622312 ADAMTS16 other 0.0797561687826932 1 0.0177096959290663 4.90392598920866 1.02108665389174 9.53094641366765e-15 242.297267146048 29.5939223021948 8.18739958400441 6.48005979477261e-15 -205.503893520287 168.236454460209 -1.22151821482241 0.222791824111429 SRD5A1 other 1.30612089652901e-10 1 9.32804607457517e-11 8.18739958400441 -1.22151821482241 7.4233672529261e-14 772.043677855999 95.7678833527235 8.06161367284769 1.6382026911119e-14 1225.90348875711 587.169805679802 2.08781765836513 0.0376277286990708 MYO10 other 1.00015026998673e-09 1 2.34934647932358e-10 8.06161367284769 2.08781765836513 0.20553327059214 0.792163644467751 5.03565265608046 0.157311017770701 0.875101166072864 -54.4555020344606 31.0685370095995 -1.75275398444526 0.0806232956873309 FAM105A other 1 1 1 0.157311017770701 -1.75275398444526 2.62410807139287e-23 5275.73908780422 477.041856976314 11.0592792029698 3.13558754894654e-24 25.2586767437943 3270.02961990576 0.00772429600944172 0.993841869866116 RPL37 essential 3.88577923211856e-19 1 4.7159236736156e-20 11.0592792029698 0.00772429600944172 5.53303500697023e-10 183.992984551275 28.0870083148091 6.55082173540937 2.31136755475447e-10 -185.111447640343 184.449295893482 -1.00358988492558 0.316341776053143 SKP2 other 6.75970886801553e-06 1 3.11757255785283e-06 6.55082173540937 -1.00358988492558 4.01958111760527e-13 649.589283407456 82.1487495665271 7.90747621643826 4.47315585885952e-14 536.22415893111 566.866384504464 0.945944535765443 0.344901919214713 OSMR other 5.3380037241798e-09 1 6.39213972231025e-10 7.90747621643826 0.945944535765443 3.2322284590835e-12 1033.07405869577 162.693338717554 6.34982395000975 7.46405493850218e-10 -370.136851855232 267.384541221901 -1.38428665383485 0.167244402030499 PLK2 other 4.20739178518899e-08 1 9.97048458685121e-06 6.34982395000975 -1.38428665383485 0.000441319748987597 -51.4670317656935 30.5888848867241 -1.68254030692145 0.0934518794839916 -205.697789077387 51.7435765295962 -3.97532994186693 8.71493838014728e-05 GZMA other 1 1 1 -1.68254030692145 -3.97532994186693 0.0714860399989681 128.607573240119 142.66683031688 0.901453918577053 0.368029250534073 -316.774574336548 197.871029290607 -1.60091437070008 0.110388804970284 PIK3R1 other 1 1 1 0.901453918577053 -1.60091437070008 0.815052237913924 -0.134097341701665 11.4465101575669 -0.0117151288782125 0.990660216453552 9.25868107341333 15.916826813635 0.581691387474418 0.56118539519171 HAPLN1 other 1 1 1 -0.0117151288782125 0.581691387474418 1.67874705421076e-05 203.773264676358 66.097760311688 3.08290725306656 0.00222824906639577 -191.649701949412 90.835799230376 -2.10984769851976 0.0356475537994909 LHFPL2 other 0.157113936803585 1 1 3.08290725306656 -2.10984769851976 0.0388463039588251 -4.69887395907508 35.3810116343683 -0.132807789885542 0.894429127768897 -117.09532523158 48.8755503720019 -2.3957853024742 0.0171606987589214 SSBP2 other 1 1 1 -0.132807789885542 -2.3957853024742 0.00686524497724575 63.8037117388174 52.631860927687 1.21226402818019 0.22630560092415 -160.642706442549 72.3975479029008 -2.21889706344754 0.027194924103582 IQGAP2 other 1 1 1 1.21226402818019 -2.21889706344754 1.44189056576853e-10 158.074305146144 45.1992716593941 3.49727549455523 0.000536505993692452 -259.956107967494 63.0275846505263 -4.12448151724189 4.74132689054781e-05 RASA1 other 1.79428862004235e-06 0.684505363188388 1 3.49727549455523 -4.12448151724189 2.38404443954597e-05 9.59972271736983 4.51586189807947 2.12577862964597 0.0342871641308991 -19.3091757915287 6.39232945071902 -3.02067907175165 0.00272529537357283 GIN1 other 0.219761216437348 1 1 2.12577862964597 -3.02067907175165 6.9980295000653e-06 62.7775797187573 32.0073106111775 1.96135128256713 0.0507048686494082 -155.522164591513 45.3072478467854 -3.43261116008281 0.000676378089774559 PPIP5K2 other 0.0677409255606321 1 1 1.96135128256713 -3.43261116008281 0.0735776377625759 416.926520102993 217.307629653215 1.91860046869194 0.0559243801714911 -125.629329116016 307.605057960022 -0.408411129352572 0.683245018701561 PAM other 1 1 1 1.91860046869194 -0.408411129352572 4.43838243130647e-07 145.608080047089 41.0791181700516 3.54457657645737 0.000452067323452388 -141.558183306879 56.4478882989159 -2.50776756354937 0.0126459862287446 BDP1 essential 0.00471001143610242 1 1 3.54457657645737 -2.50776756354937 1.10568580002169e-09 59.114437213206 13.1464497852449 4.49660845162578 9.73806082336062e-06 -46.8173496976409 17.9557760066003 -2.60736988924519 0.00956115538131186 GTF2H2 essential 1.33345707482616e-05 1 0.109436327532927 4.49660845162578 -2.60736988924519 1.89048571599942e-05 69.9794451374912 44.176096123552 1.5841020660081 0.114164438837434 -211.800750404465 60.4206872950434 -3.50543431209595 0.000521348233784527 SLC30A5 other 0.175947505588066 1 1 1.5841020660081 -3.50543431209595 3.582632927635e-14 1820.14406842878 335.467649552634 5.42569177938932 1.14132036580764e-07 -1648.103491061 461.451197055892 -3.57156618419472 0.000409369712460397 BTF3 other 4.85016845743227e-10 1 0.00141786229044283 5.42569177938932 -3.57156618419472 5.68859068656205e-07 62.0597812403841 26.2456906094264 2.36457032752244 0.0186475758237808 -136.43282601558 37.2548245889382 -3.66215188290243 0.000292551734338747 FBXL17 other 0.00599122371108715 1 1 2.36457032752244 -3.66215188290243 0.299078056616565 14.1433109501608 12.9279983868185 1.09400624342446 0.274775051523023 -11.1436725996735 18.305779211603 -0.608751611764777 0.543120978102759 TSLP other 1 1 1 1.09400624342446 -0.608751611764777 1.69250472043613e-14 163.104902223573 47.4384831849431 3.43824024869627 0.000662965726363022 -403.818801455839 70.8390529957528 -5.70051100880825 2.71425553086345e-08 TNFAIP8 other 2.30637618253831e-10 0.000411589708700133 1 3.43824024869627 -5.70051100880825 1.40232974388159e-05 117.586557317999 36.6794507038466 3.20578839272715 0.00148289484168105 -110.573000428626 54.2058333359658 -2.03987271523525 0.0421838801489461 FEM1C other 0.13216957836084 1 1 3.20578839272715 -2.03987271523525 3.58107657954206e-07 62.251439043109 13.941762344153 4.46510545126432 1.11082561040051e-05 -27.8116121835733 20.8943443516746 -1.33105933909547 0.184117037709327 COMMD10 other 0.00383103572479409 1 0.124179194986673 4.46510545126432 -1.33105933909547 3.85972324077944e-08 107.485780344884 28.0590819881003 3.8306948313729 0.000153776520255307 -113.809841659442 41.4664312747645 -2.74462590969828 0.00640003777997195 ATG12 other 0.000435222392630289 1 1 3.8306948313729 -2.74462590969828 0.17403001449954 -55.3010834348624 42.2639573603452 -1.30846912804122 0.191653241434256 -108.548132961306 62.5989249357207 -1.73402551358138 0.0838766326954109 MEGF10 other 1 1 1 -1.30846912804122 -1.73402551358138 6.51783805953332e-06 177.895879629524 46.7505961680858 3.8052109322825 0.000169829224635225 -115.278479738002 66.8319311624302 -1.72490122210933 0.0855138489681157 YIPF5 other 0.0632491005297113 1 1 3.8052109322825 -1.72490122210933 0.000773557656641681 -76.2094365272079 89.8375799450612 -0.848302420588496 0.396905644727445 -487.880057489282 128.426575291168 -3.79890265222104 0.000174016572092333 ARHGAP26 other 1 1 1 -0.848302420588496 -3.79890265222104 0.480576023571059 1138.01193801121 2629.24734516566 0.432828025900128 0.665431280281108 4713.93280116731 3889.47528585956 1.21197139837991 0.22641744569408 CXCL14 other 1 1 1 0.432828025900128 1.21197139837991 0.487300607086418 -15.9130604991705 13.3762077735173 -1.18965410590255 0.23506429002068 -11.4579881924824 19.7875751968631 -0.579049634858689 0.562963051481059 SLC25A48 other 1 1 1 -1.18965410590255 -0.579049634858689 4.41899168339976e-06 125.084279463732 63.0324345354106 1.98444309482386 0.0480629928450246 -338.535058386141 94.1238439911419 -3.59669818009134 0.000373356977352975 DDX46 essential 0.043487297156337 1 1 1.98444309482386 -3.59669818009134 4.029619013062e-09 509.105185371798 182.507299550858 2.78950588072194 0.00559519606474691 -1180.14638152409 261.692168953691 -4.50967404276026 9.12473529370815e-06 RNF145 other 4.76381559724189e-05 0.134443849817496 1 2.78950588072194 -4.50967404276026 0.850021731729951 3.13313302277016 8.52623470946233 0.367469713130585 0.713511591171527 -3.52576644148497 12.2255321273091 -0.288393699740005 0.773232101356657 C1QTNF2 other 1 1 1 0.367469713130585 -0.288393699740005 0.30541228782703 -7.53199654397173 4.96819333391103 -1.51604336581693 0.130498659293508 -5.54846896617505 7.13135016276496 -0.778039058458433 0.437122660527754 GABRB2 other 1 1 1 -1.51604336581693 -0.778039058458433 9.61853574991044e-07 81.1502621575226 25.182277850321 3.22251476375033 0.00140155572602481 -107.228854277866 36.5066820801836 -2.93723910714066 0.00355173547841917 FBXO38 other 0.00997345971908214 1 1 3.22251476375033 -2.93723910714066 0.521820523962194 200.783858772033 208.142338327424 0.964646887247822 0.335450126366777 273.130600275081 301.743401367816 0.905175056146939 0.366053648499372 SPINK7 other 1 1 1 0.964646887247822 0.905175056146939 6.28283364686089e-09 66.0909143598037 16.9286933582598 3.90407652623449 0.000115376021562102 -83.3878538863725 24.5372889164463 -3.39841349915724 0.000763461576282018 PCYOX1L other 7.36096790066222e-05 1 1 3.90407652623449 -3.39841349915724 2.3581773611655e-10 808.475051991141 208.002628724982 3.88685016601446 0.000123474755817387 -1226.03875305992 301.143150825831 -4.071282211459 5.89775872895737e-05 TNIP1 other 2.91871611991454e-06 0.848510548335097 1 3.88685016601446 -4.071282211459 5.87173850152927e-09 885.654196157735 193.71107930432 4.57203686716531 6.91113758426692e-06 -735.019722207437 283.851853643859 -2.58944837869421 0.0100522372385992 G3BP1 other 6.8916594792449e-05 1 0.0784759672693509 4.57203686716531 -2.58944837869421 0.0733623870231935 23.9796318562517 13.6582320344903 1.75569076551763 0.0800979586037266 -15.9594712153609 19.7741877340164 -0.80708605734064 0.420216369520213 ZNF300 other 1 1 1 1.75569076551763 -0.80708605734064 0.000871406508163511 19.8466755228592 31.385608269689 0.632349558189902 0.527610034989308 -157.528760583759 47.6917769494864 -3.30305915735973 0.0010646415390137 N4BP3 other 1 1 1 0.632349558189902 -3.30305915735973 2.10629536478498e-08 326.970445911924 79.4482076792738 4.11551695705809 4.91973717443299e-05 -343.874181205199 120.724956710037 -2.84841006015957 0.00467823449324386 NHP2 essential 0.000240854874963163 1 0.525132745998977 4.11551695705809 -2.84841006015957 6.19622945275594e-08 200.001868288153 76.2030258172126 2.62459221459126 0.0090914812251811 -473.416469359779 115.7937637825 -4.08844530046553 5.49813515668322e-05 RMND5B other 0.000690879583982287 0.792006369320217 1 2.62459221459126 -4.08844530046553 3.50859310562074e-06 167.332594587612 36.4255586709525 4.59382369668503 6.26729910895333e-06 -28.1024502837379 55.1758107776655 -0.509325552042697 0.61087508540036 BOD1 other 0.0347982264215465 1 0.0713594676545426 4.59382369668503 -0.509325552042697 0.244564109640119 -33.8785633305326 40.7846243697084 -0.830669985419676 0.406779412817508 -103.018891647959 62.1020860919526 -1.65886362489374 0.0981230379613921 CPLX2 other 1 1 1 -0.830669985419676 -1.65886362489374 1.21528227839329e-06 2070.64063512637 390.879304630981 5.29739131899349 2.18999552050925e-07 751.804925469859 567.499706624489 1.32476707334639 0.186193666514237 TENM2 other 0.0125149769028941 1 0.00268975249828947 5.29739131899349 1.32476707334639 0.0778228290492881 -3.75258925745854 11.5680072088722 -0.324393751637745 0.745852557346456 -37.7496294591436 17.0547853584158 -2.21343327786391 0.0275750586193476 KCNMB1 other 1 1 1 -0.324393751637745 -2.21343327786391 0.916778417658325 0.0934781184410788 15.3785321555891 0.00607848119022889 0.995153914971679 -12.9193609604346 34.1181539918379 -0.378665298348946 0.705189106976247 FAM50B other 1 1 1 0.00607848119022889 -0.378665298348946 0.037224667121705 19.9645790078914 8.89261248545115 2.24507466625299 0.0254502607020202 -4.93826525963195 19.7287698916113 -0.250307813754354 0.802510948953939 MYLK4 other 1 1 1 2.24507466625299 -0.250307813754354 1.11734490806027e-12 90.8282575667169 15.5163088753221 5.85372837680324 1.19682859598004e-08 -75.729338692637 34.7244111096804 -2.18086747255234 0.0299256587752375 FARS2 other 1.47053763349812e-08 1 0.000154247269449908 5.85372837680324 -2.18086747255234 1.22356083392789e-10 191.044297027257 32.7197752793149 5.83880223492956 1.29776469321199e-08 -87.7861652993707 77.3113781455963 -1.13548829945895 0.257025858082059 GFOD1 other 1.52516857949111e-06 1 0.000167100181897976 5.83880223492956 -1.13548829945895 2.29577281644535e-06 72.2988182749404 15.3953726238564 4.69613955058855 3.94457676302687e-06 -6.1505472984376 34.8414114567163 -0.176529797194883 0.859989760823792 CDKAL1 other 0.0230954745334402 1 0.0454634538624747 4.69613955058855 -0.176529797194883 1.22797714456256e-10 259.198470791201 60.2649778658711 4.30098010436653 2.27515539730378e-05 -359.338227969246 96.2646115291042 -3.7328175147791 0.000224863732403155 ZMAT2 essential 1.53042791526832e-06 1 0.249015758234899 4.30098010436653 -3.7328175147791 0.0178402334812223 -41.9415958220047 15.7817613078295 -2.65759917438347 0.00826501635929404 2.26897569117292 23.1728592337532 0.0979152235071606 0.922060912938036 GFRA3 other 1 1 1 -2.65759917438347 0.0979152235071606 0.623207127464484 -2.60053652548729 6.39364123704396 -0.40673794932692 0.684472368098127 6.57416703554761 9.54290340683443 0.688906379460922 0.491381357634549 KLHL3 other 1 1 1 -0.40673794932692 0.688906379460922 0.30845823017103 52.5198779387115 46.8410508744369 1.12123611572032 0.263038700607888 -46.0305291122884 75.0517312165621 -0.613317352793197 0.54010771264897 TRIM7 other 1 1 1 1.12123611572032 -0.613317352793197 3.3028381399269e-18 168.283233764559 27.6497069456041 6.0862574093688 3.34383123935802e-09 -217.969757952842 44.3021310401618 -4.92007388437461 1.39462129113809e-06 TRIM41 other 4.71777399907158e-14 0.020855166787679 4.38710658603772e-05 6.0862574093688 -4.92007388437461 1.34289876011316e-08 285.20212078559 68.9982902010287 4.13346649539641 4.56870498900607e-05 -306.209457003636 105.062577490461 -2.91454354459788 0.00381315910349718 HIGD2A other 0.000154889942991452 1 0.48939967842233 4.13346649539641 -2.91454354459788 3.32477715348852e-08 116.738277799546 35.9407979550869 3.2480713963398 0.00128522442670397 -200.416793077958 54.6135829113738 -3.66972431387979 0.000284362054982302 FAM193B other 0.000376264356364466 1 1 3.2480713963398 -3.66972431387979 0.485100298713523 -13.1035758772403 11.6623942387431 -1.12357510893513 0.262038154888588 -25.3371057769167 35.3612519740055 -0.716521739545374 0.474193484101026 PLA2G7 other 1 1 1 -1.12357510893513 -0.716521739545374 0.000289455124430477 1122.06228545274 305.39820898547 3.67409582780536 0.00028028029471736 -410.415986472398 738.528183572249 -0.555721495268093 0.578794489760009 TNFRSF21 other 1 1 1 3.67409582780536 -0.555721495268093 3.64099411824797e-07 232.295626045939 87.1697509818873 2.66486508713564 0.00809241537078845 -488.778335994451 132.731966120838 -3.68244628840555 0.000271087018200489 RNF44 other 0.00389295091123073 1 1 2.66486508713564 -3.68244628840555 9.67714051910289e-07 133.647559298728 27.4551870727217 4.86784369542739 1.78497231094265e-06 -39.4957747760501 63.0280331039264 -0.626638224786832 0.531348834370364 MUT other 0.0100313238621021 1 0.0209787795705089 4.86784369542739 -0.626638224786832 0.0040159694050864 -7.60444352548845 13.2788018705948 -0.572675426563 0.567266623187744 -66.5666296891023 20.1777085703461 -3.2990182932333 0.00107956880662204 DOK3 other 1 1 1 -0.572675426563 -3.2990182932333 1.63982045945656e-13 162.273123389925 24.7004453208142 6.569643635258 2.04325660002156e-10 -95.3746051927135 53.9528878475685 -1.76773865121312 0.0780575278691877 ABT1 essential 2.19555561316639e-09 1 2.75921371266912e-06 6.569643635258 -1.76773865121312 4.04659420642177e-10 575.70063329103 103.500488603902 5.56229870077469 5.65238350301639e-08 -372.836586109718 241.189031908779 -1.54582728393193 0.12314085061385 PPP1R18 other 4.96881302606529e-06 1 0.000710843749339341 5.56229870077469 -1.54582728393193 0.0194903342493663 35.824195155378 18.3757435255259 1.9495371768557 0.0521100559678416 -53.334789623464 42.8032675728875 -1.24604481498154 0.213665132607262 DAAM2 other 1 1 1 1.9495371768557 -1.24604481498154 3.44570615848831e-05 63.2864474352519 13.9722515907441 4.52943800963159 8.57548761416691e-06 11.5969377349573 39.167620851877 0.296084814005278 0.767372231077465 PRIM2 other 0.312732290944399 1 0.0967829532134877 4.52943800963159 0.296084814005278 0.186658454823161 33.3109349816619 19.5499028641468 1.70389260822118 0.0893936354449403 -10.4243990899798 54.122459500101 -0.192607638053854 0.84739117183977 MLIP other 1 1 1 1.70389260822118 -0.192607638053854 0.0160864968787958 -19.0962317883527 10.0044700542525 -1.90876994831283 0.0571861851760123 31.2941945602378 23.221615151472 1.3476321244715 0.178730059938809 FGD2 other 1 1 1 -1.90876994831283 1.3476321244715 0.155192213691854 215.965641868068 123.316458253423 1.75131239517311 0.0808501830471565 -38.5192424773404 284.940711329871 -0.135183359013754 0.89255189578039 SCUBE3 other 1 1 1 1.75131239517311 -0.135183359013754 0.00463185986843221 10.0782194495815 3.0843327369626 3.26755259859102 0.0012026337835711 5.72564013232612 5.56192988608704 1.02943407227204 0.304053200518541 ANO7 other 1 1 1 3.26755259859102 1.02943407227204 1.36707342192119e-22 560.511998069899 56.2254765184562 9.96900396008042 1.48415550957704e-20 -330.517514437054 195.389996890253 -1.69157848250901 0.0917029600246869 RPL7L1 essential 2.01657000467595e-18 1 2.2088686449035e-16 9.96900396008042 -1.69157848250901 0.399058059495909 20.864728440788 26.2758704115358 0.79406421610406 0.427748346084615 -59.5698646301091 73.0477611596608 -0.815491997077187 0.415399201189261 NFKBIE other 1 1 1 0.79406421610406 -0.815491997077187 0.00264370533905097 31.6373015030042 11.3136662830888 2.79637923829291 0.00548137452509271 -41.9574418056614 34.1898459158054 -1.22719014028271 0.220656017924606 CYP39A1 other 1 1 1 2.79637923829291 -1.22719014028271 0.0129359946969209 279.652688847405 129.487467020849 2.15968923696977 0.0315462473383665 -391.678805180171 276.503729138323 -1.41654076927198 0.157599155740617 TPBG other 1 1 1 2.15968923696977 -1.41654076927198 0.106797712681101 -8.20116911912922 8.05532926756573 -1.01810476601505 0.309399692710179 -37.904276889147 18.6348840373071 -2.0340495177358 0.0427736450789898 IRAK1BP1 other 1 1 1 -1.01810476601505 -2.0340495177358 0.0880917244140781 -42.431248339914 67.9301150140424 -0.624630892074049 0.532659835138203 -345.607272132712 156.529714918107 -2.20793395243534 0.027960032811345 PHIP other 1 1 1 -0.624630892074049 -2.20793395243534 0.0199935082002769 -24.1018229172855 26.2681950335102 -0.917528702925302 0.359567622016496 -160.878342272464 57.1883226101545 -2.81313273286842 0.00521430721756296 MMS22L other 1 1 1 -0.917528702925302 -2.81313273286842 0.187311927888114 -19.4599362652445 20.5889658668593 -0.945163365226026 0.345293064979471 -79.7149526855461 44.6719192381708 -1.78445327724877 0.0753033047751779 FAXC other 1 1 1 -0.945163365226026 -1.78445327724877 0.056588770531539 10.7974313326552 4.74694605635364 2.27460586332199 0.0235910597765944 -2.01849829453654 11.3996036025326 -0.17706741084296 0.85956745930438 GABRR1 other 1 1 1 2.27460586332199 -0.17706741084296 0.136633975667119 91.3612665310276 112.464225578296 0.812358472760951 0.417189882639897 -420.969266750446 270.078399004009 -1.55869283994162 0.120057507597134 PNRC1 other 1 1 1 0.812358472760951 -1.55869283994162 0.00699797821397175 91.4788911495426 37.3467755733089 2.44944549416258 0.0148433687081433 -118.562057427244 89.6868075420054 -1.32195649144624 0.187126838698486 PM20D2 other 1 1 1 2.44944549416258 -1.32195649144624 2.45269080614408e-10 106.8885257686 22.4153225329487 4.76854730113666 2.82637151003105e-06 -187.932339295468 54.0014920890101 -3.48013234496745 0.000570911321857392 RARS2 essential 3.03422379628085e-06 1 0.0328452633180708 4.76854730113666 -3.48013234496745 0.0701228971103674 -6.67914771194822 2.90230172749997 -2.30132782152241 0.0220173736125292 -2.32558626269891 6.61058786307523 -0.351797194269051 0.725222632794021 SCML4 other 1 1 1 -2.30132782152241 -0.351797194269051 7.34190001562527e-06 20.3400366000675 6.40043843405135 3.17791301481088 0.00162868856212705 -44.0411295428461 14.9455798703952 -2.94676619607677 0.00344771388444685 TBC1D32 other 0.0709374379509714 1 1 3.17791301481088 -2.94676619607677 1.39910567132216e-06 221.822123278174 52.964909689725 4.18809594083395 3.64988306889493e-05 -267.430394314781 124.639387320696 -2.14563309451037 0.0326614647229011 RNF217 other 0.0143338376026955 1 0.393895380795141 4.18809594083395 -2.14563309451037 0.489614756580363 -2.17720471689597 6.50580574044511 -0.334655660460439 0.738106869403553 -18.4637702027388 15.4448558440821 -1.19546406836898 0.232802118443574 RSPO3 other 1 1 1 -0.334655660460439 -1.19546406836898 0.0315290834080544 -19.0477719478995 22.2769114645799 -0.855045457184908 0.393165693387338 -138.365751246904 52.5519050427028 -2.63293502175554 0.00887586581114458 ARHGAP18 other 1 1 1 -0.855045457184908 -2.63293502175554 0.0128170971067107 72.2288146459636 46.0619234715531 1.56808073137829 0.117856788076347 -226.689206419159 106.330796073735 -2.13192428524622 0.0337792119002431 ABRACL other 1 1 1 1.56808073137829 -2.13192428524622 0.561948214311182 18.7274894410622 24.6135312354861 0.760861546516422 0.44730357597108 -33.1025168007276 58.5721156726278 -0.565158291118332 0.572364593466606 SLC18B1 other 1 1 1 0.760861546516422 -0.565158291118332 0.012503466561513 22.4372754928415 8.8913044909262 2.52350771652679 0.0121060006885823 -20.3884201395527 20.7009318052573 -0.984903497647134 0.325420233926168 MTFR2 other 1 1 1 2.52350771652679 -0.984903497647134 0.0641478093368052 -28.604349751117 30.1804583488189 -0.947777181529666 0.343960311788348 -163.646492157837 70.9299748519528 -2.30715564892564 0.0216861932781017 SLC2A12 other 1 1 1 -0.947777181529666 -2.30715564892564 0.000492083362837463 15.1624091643405 16.7312905260877 0.906230702329808 0.365499893194221 -129.716540000999 36.9105999824676 -3.51434384872133 0.000504804818106421 SHPRH other 1 1 1 0.906230702329808 -3.51434384872133 1.82286200565347e-05 44.8337349397592 28.9766646063247 1.54723587234306 0.12279784711916 -261.652220849209 64.8514529446025 -4.03463930210966 6.85003584683465e-05 AIG1 other 0.169927196167016 0.983665147605456 1 1.54723587234306 -4.03463930210966 0.0272106905768828 12.7685527385619 63.4900059477352 0.201111222907632 0.840739776720775 -358.224007268802 138.768328341215 -2.58145364688672 0.0102844996164899 DYNLT1 other 1 1 1 0.201111222907632 -2.58145364688672 1.55681751702554e-05 44.3041719015597 15.2092686828296 2.9129718742872 0.00383350875976501 -102.631754432841 33.5102909994882 -3.06269361953342 0.00238091745866709 TIAM2 other 0.146107323972847 1 1 2.9129718742872 -3.06269361953342 1.67262467694036e-09 181.170042131717 46.9199659052167 3.86125690069127 0.000136586708290674 -443.370793975764 102.551655765374 -4.32338991181324 2.05647548522724e-05 TMEM181 other 2.00380436297455e-05 0.300204291333472 1 3.86125690069127 -4.32338991181324 0.372292632542469 18.1510756811137 30.5804027330787 0.593552538844745 0.553230739202827 -74.093745189876 67.4726220253007 -1.09813051524947 0.272973073062892 PNLDC1 other 1 1 1 0.593552538844745 -1.09813051524947 4.34574087966309e-06 112.208716768917 64.7335811538822 1.73339269616767 0.0839891464528768 -601.238582140421 142.8282188323 -4.20952236929006 3.32906470517421e-05 WTAP essential 0.0428012019238017 0.483113870014882 1 1.73339269616767 -4.20952236929006 0.0422037828660489 94.6955740815465 41.8122625289631 2.26477995578334 0.0241989323764055 -65.8187121109347 100.292656655484 -0.656266513479932 0.512127237427696 ZMYM4 other 1 1 1 2.26477995578334 -0.656266513479932 7.75301291580693e-05 10.8212524263904 18.4214315370708 0.587427334548568 0.557330996429746 -167.023141464196 40.5963093727013 -4.11424447308282 4.94557416865496e-05 ARMT1 other 0.675907666000048 0.713596896795225 1 0.587427334548568 -4.11424447308282 0.0187701758921168 78.4820156342766 34.6187702758516 2.2670364951993 0.0240549037055066 -85.2272907183855 76.3828790023292 -1.11579049954096 0.265349005451935 SLC22A3 other 1 1 1 2.2670364951993 -1.11579049954096 0.688416338278135 1.01910664366724 3.90882223621904 0.260719618872463 0.794476957903456 -12.9551696956476 16.8478415543257 -0.768951301795765 0.442491155279631 VWDE other 1 1 1 0.260719618872463 -0.768951301795765 1.88542875940444e-15 505.613126966096 61.3013094367941 8.24799880477949 4.34944198446964e-15 -330.825388850052 279.320845969733 -1.18439204815347 0.237145168004356 GNA12 other 2.61094174602326e-11 1 6.27189534160522e-11 8.24799880477949 -1.18439204815347 2.69982299548087e-07 346.742687349301 62.1900277961956 5.57553517238519 5.31047885342383e-08 68.975629996417 300.051405427791 0.22987937649576 0.818334705832404 C7orf50 other 0.00290932925993018 1 0.000668429973280458 5.57553517238519 0.22987937649576 0.305894046332009 79.3912669618371 66.72805952911 1.18977335055282 0.235023015276346 -235.354030811062 308.638111905401 -0.762556605074098 0.44629312952627 SDK1 other 1 1 1 1.18977335055282 -0.762556605074098 0.504371818145732 -5.37609893357683 18.3144714610012 -0.293543766470394 0.769296837293591 -69.6826150153348 59.7828524212367 -1.16559535373694 0.244646149926231 WASH2P other 1 1 1 -0.293543766470394 -1.16559535373694 7.67634924506813e-12 140.796338396539 20.5385759555026 6.85521424180423 3.72661444165675e-11 -180.797917714516 98.1928933060857 -1.84125257569236 0.0665187859180146 CCZ1B other 9.9047934309114e-08 1 5.10434380073724e-07 6.85521424180423 -1.84125257569236 3.20485624740796e-13 125.659813276651 16.1860051251814 7.76348532604599 1.14140677566937e-13 -36.5097735867109 77.4306169390466 -0.471515984632427 0.637595642402733 C7orf26 essential 4.26438172280103e-09 1 1.62308043500184e-09 7.76348532604599 -0.471515984632427 9.87805051893163e-09 88.9907633300563 15.3451759404077 5.79926640630567 1.60697508089624e-08 -96.0936654164996 69.1160621621434 -1.39032321012543 0.165403056712117 RBAK other 0.000114713800676353 1 0.000206367739888695 5.79926640630567 -1.39032321012543 0.000366843247291025 73.7050941383183 18.5097229976793 3.98196635074221 8.48082573005809e-05 13.8252225005088 75.0892579061279 0.184117181152493 0.854039249854148 CREB5 other 1 1 0.885991864019168 3.98196635074221 0.184117181152493 2.06884544261261e-16 2343.69555008884 259.298708126515 9.03859323874966 2.4200828444106e-17 1667.96523348221 2177.75007904316 0.765912144618113 0.444358026254785 EGFR og 2.89845246510027e-12 1 3.54106521794159e-13 9.03859323874966 0.765912144618113 0.000947921679698556 175.18364280652 54.5255875861748 3.21287033412802 0.0014501206386938 -283.411162296243 229.831651572785 -1.23312503024193 0.218448544936765 CDCA5 essential 1 1 1 3.21287033412802 -1.23312503024193 0.00488705051627409 1349.13071728728 490.153957608075 2.75246317273651 0.00625342599797611 -3836.09518003029 2773.49089324433 -1.38312881768397 0.167592649869644 IGFBP3 other 1 1 1 2.75246317273651 -1.38312881768397 0.152722234835078 9.55887489710543 11.7034821117976 0.816754774843434 0.414678107055064 -59.9597094347155 40.5444368845737 -1.47886403270109 0.140163412973887 SSC4D other 1 1 1 0.816754774843434 -1.47886403270109 1.96262169645732e-09 1031.56204689344 177.482789073259 5.8121807318886 1.49490146507497e-08 -807.160582765662 614.854593781539 -1.3127666133246 0.190205237849795 MDH2 other 2.34572545160578e-05 1 0.000192169583335387 5.8121807318886 -1.3127666133246 8.8726652065394e-05 56.1232165285252 15.7535650983648 3.56257241951859 0.000423281617951578 -81.8068620920992 54.5751614550525 -1.49897608932361 0.134868775364057 POMZP3 other 0.768461533538378 1 1 3.56257241951859 -1.49897608932361 2.20641447997715e-22 584.672120228443 53.5467698469147 10.9189055082121 1.92176480166558e-23 -19.0345681332346 402.37210194276 -0.0473058843824674 0.962302339185091 NIPSNAP2 other 3.25026917045434e-18 1 2.88533767322071e-19 10.9189055082121 -0.0473058843824674 1.22709083405079e-23 1252.94992382928 112.100659605783 11.1770075950975 2.48360988022996e-24 1448.95395391214 842.776489543935 1.71926242828183 0.0866410503804807 CCT6A essential 1.81891674331348e-19 1 3.73758450875806e-20 11.1770075950975 1.71926242828183 3.23304376575214e-29 383.929876917472 29.8106355570581 12.8789564443409 2.89969216275824e-30 187.398890225417 224.009181574081 0.836567898282525 0.403531495397283 PSPH other 4.87769312939025e-25 1 4.40608224131114e-26 12.8789564443409 0.836567898282525 0.0096319611321283 16.2224391171492 7.06976809335073 2.29462111103854 0.0224475835962039 -38.707134801254 26.4024918238592 -1.46604097293102 0.143687978824145 ZNF92 other 1 1 1 2.29462111103854 -1.46604097293102 1.46011133661037e-09 36.1683004190033 6.87428895399271 5.26138785568449 2.64777990091429e-07 -60.7280442902231 25.0683180240793 -2.42250175029258 0.0159778447678283 ATXN7L1 other 1.75315568186808e-05 1 0.00324300082263983 5.26138785568449 -2.42250175029258 0.000655273782143701 89.3316248526865 31.915983471451 2.79896199760205 0.00544484962475315 -142.624678716035 89.8323716373749 -1.58767575781886 0.113369309815254 TMEM168 other 1 1 1 2.79896199760205 -1.58767575781886 0.0959589739725064 1.69815694069332 6.4364718443487 0.263833507200737 0.792078566687026 32.482061373677 15.7954671872474 2.05641662817683 0.0405554964424763 ASB15 other 1 1 1 0.263833507200737 2.05641662817683 1.38318170576524e-21 257.588034892109 26.366322540819 9.7695852158876 6.6966963746858e-20 -213.098026685488 115.569311774634 -1.84389803325158 0.0661223548696546 SLC12A9 other 2.02871260784587e-17 1 9.93856708967119e-16 9.7695852158876 -1.84389803325158 1.50035495652513e-12 311.765541794265 41.58068322308 7.49784557703503 6.47098466205015e-13 -16.5100167448597 178.974413681794 -0.0922479163653724 0.926558972257467 GIGYF1 other 1.96951595143053e-08 1 9.10014573024112e-09 7.49784557703503 -0.0922479163653724 2.82025058529884e-14 152.343954615212 19.8932410557426 7.65807613693167 2.27302832567702e-13 -132.315502751035 85.6730176466194 -1.54442444524138 0.123476967766593 TRIM4 other 3.82792611942612e-10 1 3.21610777800041e-09 7.65807613693167 -1.54442444524138 3.73563597373113e-10 269.140312412761 45.2077461592996 5.95341142344025 6.90237726036254e-09 -380.291355787734 195.676269873405 -1.94347202158835 0.0528356569823343 MEPCE essential 4.59109661171556e-06 1 8.96963924984113e-05 5.95341142344025 -1.94347202158835 8.13183675725349e-06 16.496877309961 3.49438781785286 4.72096349056572 3.52019058240925e-06 -5.39069722837014 15.040782459531 -0.35840537172015 0.720277036023849 ZAN other 0.0782526651150503 1 0.0406934031326509 4.72096349056572 -0.35840537172015 2.24426540112219e-10 79.7953980520798 19.5707867234871 4.07727084145865 5.75527995544427e-05 -142.517226207335 45.3077946811532 -3.14553438785264 0.00181350963341234 TMEM209 other 2.7806448319904e-06 1 0.610174780876201 4.07727084145865 -3.14553438785264 0.0108023147692764 -1.9743828024408 1.40871719178501 -1.4015466084708 0.162025915336597 -9.38780421355132 3.09740730937482 -3.0308588041158 0.00263885487493287 AGBL3 other 1 1 1 -1.4015466084708 -3.0308588041158 6.57818889450123e-09 30.3475183217504 5.95278123730969 5.09804024571642 5.88458665149152e-07 -12.8201477279367 13.0993187511388 -0.978688126573164 0.328473407176511 ZC3HAV1L other 7.69911228212424e-05 1 0.00708974999771698 5.09804024571642 -0.978688126573164 1.36299427373585e-11 88.2356267144368 22.6449736866028 3.89647733468725 0.000119027779051477 -185.164892048742 49.7904813162727 -3.71888134345521 0.000236463826024236 TMEM140 other 1.74654086236512e-07 1 1 3.89647733468725 -3.71888134345521 9.14481080128189e-09 94.9767504629329 15.6092090718087 6.08466130641221 3.3737795069429e-09 -28.9500614663276 35.9584836924617 -0.805096836505279 0.421369147960971 TLK2 other 0.000106362615808297 1 4.425386579257e-05 6.08466130641221 -0.805096836505279 3.11030119481235e-09 188.298030116342 66.2899988156121 2.84051943702849 0.00479349529832397 -534.050836557192 147.028024014949 -3.63230642685434 0.0003271934327097 EPHA1 other 3.69161648812278e-05 1 1 2.84051943702849 -3.63230642685434 2.8848763711513e-19 155.187612063032 20.7687453699221 7.47217076905276 7.74053775952398e-13 -97.8715217980248 46.7197207223736 -2.09486530066425 0.0369763499773584 NOM1 essential 4.16114567774864e-15 1 1.08770036596831e-08 7.47217076905276 -2.09486530066425 2.9666062706231e-08 108.452360334296 50.4060663087952 2.1515735758847 0.0321933074568314 -448.465133237885 114.522091431828 -3.91597051390601 0.000110491374361703 NCAPG2 essential 0.000336680145653015 1 1 2.1515735758847 -3.91597051390601 1.020857298168e-10 129.513054483997 64.5637990751771 2.00597016190441 0.045700770256654 -719.656013643798 142.075065444946 -5.06532241523171 6.90136858133959e-07 LUC7L2 other 1.27586745125036e-06 0.0103568838300163 1 2.00597016190441 -5.06532241523171 4.08914424955434e-07 71.7487627608054 13.9764269486423 5.13355545193727 4.94518883098145e-07 14.8990574661332 30.7556525771158 0.484433143753842 0.628409899300503 DENND2A other 0.00434839599497609 1 0.00597823877777348 5.13355545193727 0.484433143753842 9.9226619868822e-32 77.8074474344531 17.9429997574622 4.33636785856245 1.9451617979142e-05 -240.392956652057 34.5928102994616 -6.94921732495955 2.07543499974916e-11 MCPH1 other 1.50308483777292e-27 3.17749098461597e-07 0.213948346152583 4.33636785856245 -6.94921732495955 1.37555928399803e-19 543.59330703718 104.954399905423 5.1793284276507 3.9601409330754e-07 -626.754988634849 198.208579901718 -3.16209817428503 0.00171738765420037 MFHAS1 other 1.99098450765875e-15 1 0.00480919514912677 5.1793284276507 -3.16209817428503 1.1468605447652e-24 107.403575138483 31.6569496471984 3.39273291758823 0.000784922004764497 -387.688705499168 60.5357712244619 -6.40429117623114 5.82316035126892e-10 FBXO25 other 1.70733129299196e-20 8.89429512052815e-06 1 3.39273291758823 -6.40429117623114 0.493745128030524 17.3694776712649 29.9876414329569 0.579221200510139 0.562849998914061 -24.6850783259293 55.422802306308 -0.445395708962912 0.656336862009261 CSGALNACT1 other 1 1 1 0.579221200510139 -0.445395708962912 3.93069052062614e-23 203.606849933219 81.0304564925164 2.51272001598588 0.0124733234697147 -1015.44053818417 149.812591881157 -6.77807202607972 5.89705046948202e-11 ATP6V1B2 essential 5.81506355621431e-19 9.02307692335444e-07 1 2.51272001598588 -6.77807202607972 1.3063877912563e-39 201.347608223041 29.5205150270955 6.82059943866947 4.53608032328478e-11 -361.290323824493 54.1623635572766 -6.67050512746602 1.12130312381028e-10 CCDC25 other 1.99472351846925e-35 1.71492099755544e-06 6.19991458586564e-07 6.82059943866947 -6.67050512746602 1.44165333228993e-28 35.3834326944603 7.96779755231448 4.44080468437381 1.2357684530306e-05 -94.334157841263 14.6169315921407 -6.45375927544089 4.03827039409038e-10 HMBOX1 other 2.17156241442832e-24 6.17209247032774e-06 0.137775824828381 4.44080468437381 -6.45375927544089 1.05878203908674e-06 1.150392733038 1.96476547881529 0.585511474749476 0.558616532552858 -13.7366934183803 3.61257893968374 -3.80246180020716 0.000171548047157906 GNRH1 other 0.0109414535919223 1 1 0.585511474749476 -3.80246180020716 1.88711896184434e-24 105.940132108138 23.3202853658762 4.5428317212257 7.87455290185555e-06 -227.271527001638 43.1240108972354 -5.27018526971498 2.51063693065318e-07 BIN3 other 2.80576847247016e-20 0.00378478517295967 0.0890454442141825 4.5428317212257 -5.27018526971498 0.16799442285778 -23.6770569682943 17.5871000941896 -1.34627407824424 0.179167012035703 -61.2326353537149 32.5221704714808 -1.88279670347988 0.0606348987978994 DOK2 other 1 1 1 -1.34627407824424 -1.88279670347988 1.81359184206693e-09 126.98373143146 53.4701956906252 2.374850695632 0.0181452102703133 -320.835520310664 98.8638106555995 -3.24522712793584 0.00129771361727039 SLC25A37 other 2.17002245085651e-05 1 1 2.374850695632 -3.24522712793584 5.99639405919861e-39 163.742516392686 30.6467214675544 5.34290483783197 1.74368530113809e-07 -442.66343128343 56.6533224503519 -7.81354759328295 8.12290834992708e-14 CHMP7 essential 9.15349553136667e-35 1.24597291179532e-09 0.00214978960777316 5.34290483783197 -7.81354759328295 3.964052591844e-07 164.596586990545 41.8285351496915 3.93503110738889 0.000102072531972805 -46.2991693686171 77.0582066361303 -0.600833725436179 0.548376063220546 DOCK5 other 0.00422052679453631 1 1 3.93503110738889 -0.600833725436179 0.00123655088247965 19.2869418987967 21.0617281484376 0.915734063362105 0.360572502200334 -126.232897688751 49.3467074188829 -2.55808146665622 0.0110370437428839 STAR other 1 1 1 0.915734063362105 -2.55808146665622 3.87312144549797e-24 137.03233276747 31.5318440220536 4.34583948441545 1.91547631894517e-05 -480.792039957215 72.3995425616152 -6.64081599062646 1.51312160846812e-10 PLPBP other 5.75274728299813e-20 2.31326031502607e-06 0.210779014136726 4.34583948441545 -6.64081599062646 7.77774280864791e-22 257.979209743147 45.0602980140624 5.72519981254089 2.5562328942189e-08 -482.120409945566 103.461914933566 -4.65988291686985 4.80864424800409e-06 ERLIN2 other 1.14208375402186e-17 0.0713266201306446 0.000325868569355025 5.72519981254089 -4.65988291686985 0.935955046266647 0.301782941743485 2.46719824245103 0.122318075844477 0.902729840660093 -3.77735058143666 11.7831982023186 -0.320570910934299 0.748761017456276 PXDNL other 1 1 1 0.122318075844477 -0.320570910934299 1.18759818887927e-07 68.2977418556778 12.4974779821572 5.46492195890941 9.61409111561824e-08 -64.1675529922861 58.0963771695221 -1.1045017971611 0.270243255024338 RGS20 other 0.00130469537030277 1 0.00119810803482835 5.46492195890941 -1.1045017971611 1.98402254038758e-06 2.25755976595634 71.314382772742 0.0316564440184601 0.974768423341116 -748.626839138865 169.288878046282 -4.42218560237725 1.39631298422939e-05 TACC1 other 0.0200505317931569 0.204881004175978 1 0.0316564440184601 -4.42218560237725 1.64953978914302e-32 185.446618290428 25.3017818316337 7.32938966608953 2.56342567485183e-12 -380.588602822301 61.4915732876688 -6.18928061966861 2.17809037533855e-09 GOLGA7 other 2.50119718227756e-28 3.32049877720362e-05 3.57905492722812e-08 7.32938966608953 -6.18928061966861 1.1415522574452e-14 76.7134854539768 23.0473727081424 3.32851325074787 0.000987492515430973 -260.694699568006 53.6521215658528 -4.85898212334489 1.94729554661586e-06 PLPP5 other 1.56152933295929e-10 0.0290633860332417 1 3.32851325074787 -4.85898212334489 2.27176600124115e-15 21.5769606317631 19.2760309726512 1.11936739790346 0.263960168152357 -318.337089910069 46.864843319522 -6.79266305745788 6.79217826019268e-11 GINS4 essential 3.14207955631664e-11 1.03913535202688e-06 1 1.11936739790346 -6.79266305745788 3.60683220890127e-21 222.423851011683 60.1433211006553 3.69823027630011 0.000260422118971472 -902.490956580851 142.44673478642 -6.33563807506026 9.19454306695709e-10 NSD3 other 5.27607415518077e-17 1.40345505374033e-05 1 3.69823027630011 -6.33563807506026 0.250609390807815 9.15552165144412 5.51814744197965 1.65916582471011 0.0980744922500063 10.1504375937768 26.0937378537453 0.388998987062327 0.697538885192698 TRIM55 other 1 1 1 1.65916582471011 0.388998987062327 1.16752304194252e-06 30.0626812394062 5.70182342610994 5.27246794450744 2.50033002300609e-07 -3.57909428003751 26.9622889445449 -0.132744452349683 0.894479973932331 ADHFE1 other 0.0120348275163435 1 0.00306415444319397 5.27246794450744 -0.132744452349683 5.25917823336431e-16 124.958441986431 14.1562444980904 8.82708984033778 7.40899639086179e-17 -7.20379329438754 67.9882054372125 -0.105956514781675 0.915683871215788 MRPS28 other 7.3349758820732e-12 1 1.08104666339064e-12 8.82708984033778 -0.105956514781675 1.93025526918153e-06 50.0307945314976 10.1257895664116 4.94092773737423 1.26118720853467e-06 -50.9397633904139 47.1033538741342 -1.08144663173096 0.280320489761486 LACTB2 other 0.0195264623030403 1 0.0149665086036809 4.94092773737423 -1.08144663173096 1.95586599987436e-07 52.6111065710715 9.83903366711458 5.34718228954901 1.7129008577721e-07 -57.9599395993142 45.5479553296372 -1.27250365422223 0.204126784388082 TERF1 other 0.00212250578306366 1 0.00211234933780455 5.34718228954901 -1.27250365422223 5.82437260152331e-07 641.597898061701 119.783343063404 5.35631984926394 1.63537923080682e-07 -313.136598353824 554.077544371637 -0.56514941190938 0.572371881463027 RPL7 essential 0.00612840485132283 1 0.00201838504666178 5.35631984926394 -0.56514941190938 0.0842294368421498 6.48215353034845 3.0775983910627 2.10623762644682 0.0359646247041187 -8.1076614166209 15.7343683325431 -0.515283565585024 0.606711770503743 ATP6V0D2 other 1 1 1 2.10623762644682 -0.515283565585024 0.171134739726377 -19.5879666817602 13.7954975647176 -1.41988113077248 0.156618807526967 88.5602554679192 75.4999263020972 1.17298466111826 0.241677084235742 SYBU other 1 1 1 -1.41988113077248 1.17298466111826 2.90784866547293e-15 685.11898369126 80.2668851537328 8.53551227731178 5.75998032480247e-16 890.023157440779 423.169601208738 2.10323037122356 0.036228532414917 MTDH other 4.011958803753e-11 1 8.35888344735334e-12 8.53551227731178 2.10323037122356 4.16215665645939e-05 134.411950368988 29.9560102697224 4.48697771027416 1.00880624219324e-05 170.667707295975 167.928774657198 1.01631008529877 0.310249529293254 LRP12 other 0.374677342214474 1 0.113198148436503 4.48697771027416 1.01631008529877 1.12848724505587e-12 75.1208693912365 9.75323954003734 7.70214543412608 1.70030623179238e-13 -26.8349521392543 53.377477907198 -0.50273922994094 0.615494521273712 EBAG9 other 1.48497636576902e-08 1 2.41103423668159e-09 7.70214543412608 -0.50273922994094 1.34215100927667e-09 131.578471877344 20.3152444026438 6.4768343057798 3.54200897570689e-10 -128.775358643547 117.772149766252 -1.09342793605393 0.27503095269143 POLR2K other 1.61380237355426e-05 1 4.76223106783792e-06 6.4768343057798 -1.09342793605393 0.869250943919423 149.491616831165 282.863464673239 0.528493904307708 0.597522911277231 -1.77457632761584 1570.30148343196 -0.00113008638553752 0.999099025873045 MAL2 other 1 1 1 0.528493904307708 -0.00113008638553752 1.27408533242764e-16 861.888913675431 95.5695718335048 9.0184448579194 1.83862980523525e-17 -248.936393359096 523.485476860077 -0.475536388998304 0.634731187709888 EIF3H essential 1.78830617259543e-12 1 2.69193789784493e-13 9.0184448579194 -0.475536388998304 6.4853816945488e-13 112.7978974813 14.4070728235575 7.82934180056757 7.3666350340599e-14 58.3182030487027 78.9152158213792 0.738998207654949 0.460453191437401 UTP23 essential 8.57756582921024e-09 1 1.0500401577549e-09 7.82934180056757 0.738998207654949 2.15976564154869e-07 625.26561358104 114.649834774231 5.4536983399262 9.9453547582688e-08 -818.954731024332 674.637869287579 -1.21391752272838 0.22568283430013 NDUFB9 other 0.00233989009605385 1 0.00123879338868996 5.4536983399262 -1.21391752272838 6.85886072974532e-06 1936.62024467396 407.044480670947 4.75776072797193 2.97103215080289e-06 -2615.84355561845 2301.67053837806 -1.13649782277779 0.256601308075853 FAM83A other 0.0664555016105024 1 0.0344877412065199 4.75776072797193 -1.13649782277779 0.00144743872591887 178.738948779795 53.8179666881336 3.32117617552439 0.00100105789617958 -393.476962428057 312.79293759274 -1.25794707980386 0.209336712645002 GSDMC other 1 1 1 3.32117617552439 -1.25794707980386 6.13416010209116e-19 100.501900664786 10.2584255730788 9.79701026720252 5.70770659868408e-20 46.8562570623696 51.232962885729 0.914572463179197 0.361111246789152 ZNF7 other 8.82521613887856e-15 1 8.47537352838599e-16 9.79701026720252 0.914572463179197 2.88585546107717e-10 68.7810481846356 10.0594777003048 6.8374373137237 4.13291413083705e-11 7.80620036161365 50.3156336779658 0.155144629829677 0.87680572651274 ARHGAP39 other 3.56201139560755e-06 1 5.65299994815891e-07 6.8374373137237 0.155144629829677 2.04512311664782e-06 180.341690926128 34.5173119691167 5.22467366773759 3.15151411167925e-07 117.865059593944 170.101474567996 0.692910275429908 0.488868425364553 SLC39A4 other 0.0206332471238599 1 0.00384264115637051 5.22467366773759 0.692910275429908 0.0664605879122184 233.384596080006 106.3327485033 2.19485153318278 0.0288946093913968 -284.57928899469 522.970574189395 -0.544159275951211 0.586712007831156 NAPRT other 1 1 1 2.19485153318278 -0.544159275951211 1.42286360580066e-11 184.66384459102 35.4666256315233 5.20669337166621 3.48281677263855e-07 -479.51865589528 113.747328379236 -4.21564763522668 3.26047173250275e-05 VLDLR other 1.82240370630949e-07 0.473257471972774 0.00423789144894659 5.20669337166621 -4.21564763522668 7.803147527715e-34 428.726471617495 34.1148239959153 12.5671605888639 1.32703613967233e-29 -457.287854593196 114.858561988114 -3.98131272652114 8.52578950612331e-05 AK3 other 1.18514204650935e-29 1 2.0144408600226e-25 12.5671605888639 -3.98131272652114 1.09820532958441e-36 285.22734078306 20.8011082936011 13.7121222945031 7.38861556859961e-34 -214.824325323475 69.9952904765323 -3.06912542059526 0.00233411560800152 UHRF2 other 1.67322564015481e-32 1 1.12572946803184e-29 13.7121222945031 -3.06912542059526 8.10427709429983e-12 358.448975351698 62.3380695214502 5.75008142060539 2.12556775464269e-08 -907.893336501908 234.312822619774 -3.87470615714092 0.0001301283194907 NFIB other 1.04488444576808e-07 1 0.000271732581753522 5.75008142060539 -3.87470615714092 0.619359899992482 24.8184924275242 30.0812196065104 0.825049407975227 0.40996395697654 72.0584437947501 112.576141548999 0.640086281189396 0.522578864547549 PLIN2 other 1 1 1 0.825049407975227 0.640086281189396 9.36151920874199e-59 376.252366874853 18.7435434908378 20.0737052232825 2.04716452331267e-58 -82.0975322241109 70.1459526161531 -1.17038159953944 0.242726548253514 HAUS6 other 1.43643150738937e-54 1 3.14137396102329e-54 20.0737052232825 -1.17038159953944 0.00540268375524262 531.403107578913 162.97466973018 3.2606484704568 0.00124603917479674 228.521758771355 362.687675375876 0.63007864420682 0.529146202833985 CDKN2B other 1 1 1 3.2606484704568 0.63007864420682 3.7328208734412e-12 199.473245929981 160.234360795376 1.24488433654198 0.214200523520979 -2543.7658383717 356.030923992745 -7.14478902519022 7.61013200807748e-12 CDKN2A ts 4.85266713547356e-08 1.16572002099731e-07 1 1.24488433654198 -7.14478902519022 4.27853291375163e-05 26.7763294102462 14.1255908231798 1.89559004967826 0.0589502797834819 -111.190544250786 31.7643239920315 -3.50048514423539 0.000533004489236067 C9orf72 other 0.384640108946272 1 1 1.89559004967826 -3.50048514423539 3.89516552779648e-47 146.894198673533 9.46791055050606 15.514954211907 1.15204619799088e-40 -126.785575076621 29.1175726523614 -4.35426320010706 1.81106333522819e-05 ZCCHC7 other 5.96466697271476e-43 0.264868012777123 1.76159384134785e-36 15.514954211907 -4.35426320010706 2.36947979323942e-32 116.045401988613 9.2887128543408 12.4931628104299 2.5620686964487e-29 -61.2188800172218 27.5123736678426 -2.22513988637689 0.0267865589124997 FBXO10 other 3.59213136655096e-28 1 3.88819545373055e-25 12.4931628104299 -2.22513988637689 1.46566784014804e-38 728.295056552226 50.6866090091727 14.3685890768591 2.6386168616258e-36 -374.337107018959 161.13405257856 -2.32314089435847 0.0208121632327181 SIGMAR1 other 2.23690225763393e-34 1 4.0270570542133e-32 14.3685890768591 -2.32314089435847 2.63769015509756e-06 63.1004605501576 25.6105494549782 2.46384641848799 0.014271034533596 -196.997347042582 49.3001117440898 -3.99588033522457 8.00440620890867e-05 CEP78 other 0.0264191045934571 1 1 2.46384641848799 -3.99588033522457 0.908856967493901 -222.549504162178 568.857715277722 -0.391221738204829 0.695893701756876 129.012155566509 1097.76023459319 0.117523072435138 0.906519290751493 NTRK2 other 1 1 1 -0.391221738204829 0.117523072435138 0.00106053769841035 11.0618458800569 3.2508764282581 3.4027272719142 0.000752202719370864 -5.59727314495183 6.22313272588482 -0.899430140975501 0.36910202454509 IDNK other 1 1 1 3.4027272719142 -0.899430140975501 0.345410360092363 3.51737850621146 8.09994686556638 0.434247108603164 0.66440257231582 -20.1787590808938 15.3807108295037 -1.31195230861413 0.190479542680573 SHC3 other 1 1 1 0.434247108603164 -1.31195230861413 2.52699565019527e-07 36.883753042799 7.5351212195659 4.89491170321529 1.56234062236408e-06 -29.6404469243461 14.3970316606895 -2.05878875749631 0.0403235623034685 AUH other 0.00272713370569073 1 0.0184356193438961 4.89491170321529 -2.05878875749631 2.20703534978906e-12 507.720700652321 69.9909811364245 7.25408748968221 3.07118564827111e-12 -183.923742260749 133.519477867114 -1.37750495432435 0.169318843026046 MFSD14B other 2.88444676616518e-08 1 4.2821541493844e-08 7.25408748968221 -1.37750495432435 0.0400327478367914 5.67244811436462 4.45263419321457 1.27395332026353 0.203604430737692 20.0386269852623 8.52387972747033 2.35088101028488 0.0193354819139104 PLPPR1 other 1 1 1 1.27395332026353 2.35088101028488 0.0201951571283152 72.8532308116682 26.5967200284022 2.73918102434697 0.00650448856781463 -19.494655540997 53.2405031513227 -0.366162120699505 0.714486064558285 ZNF462 other 1 1 1 2.73918102434697 -0.366162120699505 1.85104722138998e-06 62.7296226587378 15.9801768638039 3.92546485519972 0.000106020099136159 -99.4869416045425 31.9805243536154 -3.11086023807785 0.00203338166663713 INIP other 0.0187418531165736 1 1 3.92546485519972 -3.11086023807785 0.0839406782963742 165.948105069743 88.3498472169923 1.87830664451706 0.0612482988373599 -183.576425867143 176.340644365722 -1.04103297641588 0.298646128111976 UGCG other 1 1 1 1.87830664451706 -1.04103297641588 0.000136544848353653 79.1406789845281 22.7421314617758 3.47991476161964 0.000571131018771726 -98.4756021230786 45.512968677702 -2.16368224231711 0.0312284680777906 SNX30 other 1 1 1 3.47991476161964 -2.16368224231711 0.000693464719498882 757.395631214271 225.034464824835 3.36568725952188 0.000856795615213777 -657.763108770913 449.409088028849 -1.46361772890692 0.144283080837095 STOM other 1 1 1 3.36568725952188 -1.46361772890692 0.00737987491937552 1804.15520331844 571.363382086824 3.15763183270342 0.0017426024279186 424.118960955313 1141.59338610162 0.371514907250488 0.710500689741391 GSN other 1 1 1 3.15763183270342 0.371514907250488 3.04980244622162e-15 203.073436108666 27.6916743485465 7.33337513480201 1.85382289332356e-12 -197.53654166449 55.3693991772099 -3.56761215761568 0.000415353118580264 MRRF other 4.205372593095e-11 1 2.593127463181e-08 7.33337513480201 -3.56761215761568 1.89857077037247e-05 24.8833539240645 6.14591852047559 4.04876078997203 6.47768281647296e-05 -23.64072173249 12.0762685966483 -1.95761807906884 0.0511519358350329 NR6A1 other 0.176609858279475 1 0.684431966388533 4.04876078997203 -1.95761807906884 0.0757805341087529 -27.6463278134395 21.4187414651142 -1.29075407434505 0.197723648834997 -86.2201124263606 42.5244339354968 -2.0275428605856 0.043437947781238 CRB2 other 1 1 1 -1.29075407434505 -2.0275428605856 1.64252053535475e-08 186.850411037181 33.2325934687679 5.62250464179944 4.10300294373418e-08 -132.733274522568 66.5071340461214 -1.99577498604165 0.0468057323940093 ALAD other 0.000188791310333675 1 0.000518537512029126 5.62250464179944 -1.99577498604165 0.0225205960938658 -43.5966310858783 27.9794989652088 -1.55816339456574 0.120186030080647 -137.363662519204 55.9294770572477 -2.45601549927962 0.0145814600385805 ASTN2 other 1 1 1 -1.55816339456574 -2.45601549927962 0.0632396740933889 5.75886211477234 5.05024388067588 1.14031366619895 0.255008391413698 -19.7557784768307 10.1068623203715 -1.95468958125715 0.0514901783503844 WDR31 other 1 1 1 1.14031366619895 -1.95468958125715 3.10152696285171e-10 448.647839367085 76.8774817923957 5.83588105264216 1.31153396155182e-08 -468.479862467246 153.852000491633 -3.04500338617777 0.00251999424844665 POLE3 other 3.82449289789245e-06 1 0.000168846882210181 5.83588105264216 -3.04500338617777 4.4946320597607e-12 1291.57586690961 171.933091235167 7.51208425109403 5.8617675732555e-13 486.3620209798 360.586374339805 1.34880865054947 0.178352156340151 SURF4 other 5.83403241356939e-08 1 8.24633462205584e-09 7.51208425109403 1.34880865054947 0.00263139533165716 25.3042217601659 7.64998933057549 3.30774601985782 0.00104756827791058 22.2686185185933 16.0018101323675 1.39163121761767 0.165000681973553 GBGT1 other 1 1 1 3.30774601985782 1.39163121761767 2.75378049144723e-08 193.682267869696 34.9189566942184 5.54662241388686 6.10727927292191e-08 -136.785843764237 73.2337207435812 -1.86779863668509 0.0627040290030881 SURF1 other 0.000312967152852977 1 0.000766952131093534 5.54662241388686 -1.86779863668509 3.38846573467156e-06 166.305214376849 34.8417850721625 4.77315424661527 2.76318962002917e-06 -98.5697872526758 73.071872694441 -1.34894294641739 0.178309058131091 SURF2 other 0.0336542416767579 1 0.0321414216601793 4.77315424661527 -1.34894294641739 3.42990499698889e-11 230.774372137401 36.7695049986275 6.27624364663095 1.12711098860719e-09 -222.590460203233 77.1147799325586 -2.88648246675801 0.00416063007151434 SURF6 essential 4.3528924316786e-07 1 1.49804321495782e-05 6.27624364663095 -2.88648246675801 5.15096877360748e-17 178.459103624698 23.7025162368505 7.52912061493479 5.24733399135762e-13 -222.327069386975 49.7100606472905 -4.4724763255563 1.07538725356149e-05 MED22 essential 7.25977538952238e-13 0.158167957253824 7.38719679303326e-09 7.52912061493479 -4.4724763255563 1.52436814730128e-17 255.886289412619 29.6904135471548 8.61848182094923 3.17260698874571e-16 -170.921828414064 62.2681677896117 -2.74493106962077 0.00639422893199217 REXO4 other 2.1639930219089e-13 1 4.61043247604527e-12 8.61848182094923 -2.74493106962077 2.98091816497486e-14 3058.46920879113 436.631224658142 7.00469649458932 1.46618593434598e-11 -3381.407876178 915.724070869408 -3.69260564808308 0.000260907424238014 RPL7A essential 4.0436154907884e-10 1 2.02216364064997e-07 7.00469649458932 -3.69260564808308 1.05709753330478e-10 364.13090686423 66.7491950906355 5.45521045414546 9.80724497081117e-08 -542.615091301003 139.622148498913 -3.88631099818113 0.000123736727786336 GTF3C5 essential 1.320420528851e-06 1 0.00122178657846366 5.45521045414546 -3.88631099818113 1.09626112103339e-11 246.630324009401 38.1004220985715 6.4731651363686 3.60508067597955e-10 -209.496839364028 74.6000803074601 -2.80826560106367 0.00528685920429697 ASB6 other 1.40814740996739e-07 1 4.84667046078691e-06 6.4731651363686 -2.80826560106367 2.059979254225e-11 295.670863707798 46.902414916806 6.30395821264747 9.6489689128252e-10 -266.909676942934 91.6894733812726 -2.91101766756848 0.00385611994624305 PTGES2 other 2.62976951594364e-07 1 1.28476021074268e-05 6.30395821264747 -2.91101766756848 4.79682816234186e-09 248.301798314976 42.6320691174151 5.82429620366573 1.39646909916016e-08 -160.150545825505 83.4729802101483 -1.9185914462658 0.0559255274837273 NTMT1 other 5.65306198931988e-05 1 0.00017961385553398 5.82429620366573 -1.9185914462658 1.90973529037283e-16 574.704478346202 67.8146154046863 8.47464038418019 8.83397876511392e-16 -273.712494708629 132.570708460072 -2.06465287760808 0.0397637627063101 CIZ1 other 2.67611206239944e-12 1 1.27986684348971e-11 8.47464038418019 -2.06465287760808 0.184432654141655 140.424891650399 79.7620556711641 1.76054754944293 0.0792732293823695 116.710193027143 155.926744779964 0.748493744237644 0.454713893166506 SLC25A25 other 1 1 1 1.76054754944293 0.748493744237644 4.54775595050128e-11 216.769594776726 65.093296751907 3.3301369817373 0.000969459365684705 -751.042179842886 127.205483066385 -5.90416514869048 9.04315789803781e-09 SH3GLB2 other 5.75382082857422e-07 0.000137465043208073 1 3.3301369817373 -5.90416514869048 8.59750922150457e-08 62.6475957073566 18.9275125335819 3.30986946098728 0.00103991711038923 -162.689065407213 36.9881922597321 -4.39840542259556 1.48668559536732e-05 MIGA2 other 0.000952775971927136 0.217948108280849 1 3.30986946098728 -4.39840542259556 0.0597482184575242 76.5442645388997 154.306654809801 0.496052906034731 0.620197615769154 -682.811418377363 302.130218164125 -2.25999048531598 0.024493796621843 PTGES other 1 1 1 0.496052906034731 -2.25999048531598 0.206672772110357 839.7643927898 804.312902720545 1.04407673922592 0.297240432083474 -2060.37956475026 1572.35030680232 -1.31038201591378 0.19100933402731 LCN2 other 1 1 1 1.04407673922592 -1.31038201591378 5.57590324446402e-15 136.092586833567 17.7269903382171 7.67714001288584 1.99101731796758e-13 -95.3761540577309 34.7249745788597 -2.74661551849761 0.00636225041870879 LRSAM1 other 7.66463659984024e-11 1 2.82047513263287e-09 7.67714001288584 -2.74661551849761 0.355675331259736 -15.1624793242315 10.7731062445615 -1.40743802019828 0.160271176978431 3.50204957174333 21.8464211680675 0.160303124470667 0.872743758114057 HMCN2 other 1 1 1 -1.40743802019828 0.160303124470667 0.000584429797352506 313.98426726666 91.4620787349471 3.43294479646119 0.000675831761621563 -278.133404141392 185.47288475497 -1.49959065180249 0.13470946715801 GPR107 other 1 1 1 3.43294479646119 -1.49959065180249 1.24543469129897e-09 19.0366828753994 3.78083722692651 5.03504428591191 8.06751030435249e-07 -9.39640757505042 7.49232990614149 -1.25413692306156 0.210725064899259 IDI2 other 1.49925428138571e-05 1 0.00965519633224906 5.03504428591191 -1.25413692306156 6.51517023241757e-09 77.095923451445 13.956348934954 5.52407537320569 6.89769717403242e-08 -67.5608473020655 28.9140154155479 -2.33661241204624 0.0200800124034521 INPP5E other 7.62730979109125e-05 1 0.000864281455906263 5.52407537320569 -2.33661241204624 2.95151344584119e-15 663.268403616479 82.2196956042301 8.06702577456823 1.48716799553167e-14 -338.44370540228 170.338356918575 -1.986890748066 0.0477923183427775 SEC16A essential 4.07131764719333e-11 1 2.13378863998884e-10 8.06702577456823 -1.986890748066 9.51818269094451e-08 99.9351481996064 19.2078975016106 5.20281557058635 3.5440785750852e-07 -80.2842161630195 40.5350650672043 -1.98061150339623 0.0485044947792331 DPH7 other 0.00105233027831083 1 0.00431172599444866 5.20281557058635 -1.98061150339623 6.59890645418994e-07 278.287281707933 175.691172755071 1.58395710691675 0.114206893544137 -1823.21656725633 366.701960881774 -4.97193023694831 1.09095931933838e-06 NOTCH1 og 0.00691565396399106 0.0163382067664115 1 1.58395710691675 -4.97193023694831 0.992252318590521 0.675297741753541 18.5438610851696 0.0364162424778736 0.970973901389447 4.77030048549057 38.9349034931475 0.122519900077064 0.902566675405032 CACNA1B other 1 1 1 0.0364162424778736 0.122519900077064 0.000194360210950316 67.7564194158435 20.097589196855 3.37137050380384 0.000840211882192776 -86.9040867915732 41.8189564769238 -2.07810271017948 0.038501711548307 NACC2 other 1 1 1 3.37137050380384 -2.07810271017948 0.000361995869158431 15.6558877271679 50.4070000002834 0.310589555559345 0.756316139446867 -342.046459137761 103.178997091785 -3.31507834713189 0.00102205130418164 PROSER2 other 1 1 1 0.310589555559345 -3.31507834713189 3.08951379566678e-09 133.881655057829 42.6694112626478 3.13764945650953 0.00186302449454083 -277.492765129173 84.6208730253148 -3.27924724962551 0.00115656757694741 USP6NL other 3.66725287545647e-05 1 1 3.13764945650953 -3.27924724962551 1.13768626132283e-06 48.3746079813285 30.0645757310236 1.60902347048293 0.108597271557377 -209.426557862054 59.8258839772549 -3.5006011435063 0.000530101587121751 COMMD3 other 0.0117340960992837 1 1 1.60902347048293 -3.5006011435063 0.0308684014788661 30.0519509581073 27.3572792748847 1.09849925704039 0.272814945277764 -80.544496583657 54.4621888404736 -1.4789067112154 0.140152009877365 MSRB2 other 1 1 1 1.09849925704039 -1.4789067112154 3.96055757880363e-14 33.6640782057277 6.84501088775728 4.91804596920919 1.4020968339382e-06 -46.7688330204426 13.8052409359865 -3.38775927470625 0.000792946361728684 PDSS1 other 5.35863440412131e-10 1 0.0165896097391567 4.91804596920919 -3.38775927470625 0.0283372781374843 45.3178397909854 52.9763126566481 0.855435901790692 0.392951915867161 -184.859225081764 105.871179667227 -1.74607693673397 0.081760222571516 FAM171A1 other 1 1 1 0.855435901790692 -1.74607693673397 2.93267168428527e-11 45.9951554793199 11.6274646079634 3.95573386203378 9.4061023817515e-05 -73.9810725570159 23.2127495196201 -3.18708787575918 0.00157945247757664 MINDY3 other 3.73035838241086e-07 1 0.977388098487798 3.95573386203378 -3.18708787575918 3.7404253409682e-09 162.553933586925 51.8064910443937 3.13771363993038 0.00186109234431159 -331.42156437525 102.964749484303 -3.21878668219143 0.00141931872974068 RSU1 other 4.42679339103586e-05 1 1 3.13771363993038 -3.21878668219143 2.6582189959436e-10 497.870246288445 117.357214598089 4.24234886618169 2.94252134455534e-05 -613.533093314574 236.715566718479 -2.5918578225328 0.0100083707261177 PARD3 other 3.2852928570867e-06 1 0.31955781801871 4.24234886618169 -2.5918578225328 0.333843114177405 22.6967487422038 27.286466914512 0.8317950731149 0.406154734700402 88.2555966446645 59.7851749552455 1.47621206613064 0.140885906145626 ZEB1 other 1 1 1 0.8317950731149 1.47621206613064 0.893471399178966 -2.45855600925286 8.95815242294055 -0.274449003899158 0.783918919179565 -9.38161904324961 20.4857636914418 -0.457957984117961 0.647297372276145 FAM13C other 1 1 1 -0.274449003899158 -0.457957984117961 1.58631733724164e-06 105.61771603984 31.3807507040306 3.36568481219521 0.000858029476808812 -192.55149253182 72.0845249359122 -2.67119042128683 0.00795100790021885 NRBF2 other 0.0161661599838295 1 1 3.36568481219521 -2.67119042128683 0.00314345276670649 295.374110258655 87.0123535335843 3.39462269739261 0.000774297717616439 181.186035283168 174.00574083017 1.04126469861708 0.298543706918625 CDHR1 other 1 1 1 3.39462269739261 1.04126469861708 1.18808753399707e-15 134.072795991914 22.921964242765 5.84909716165499 1.22402897281528e-08 -202.038660706438 53.3312161085133 -3.78837527903637 0.000181222487816775 POLR3A essential 1.64894668843454e-11 1 0.000157691652567793 5.84909716165499 -3.78837527903637 1.58374357494026e-06 124.069617983326 37.5385396997558 3.3051263841287 0.00105742808700213 -203.090835261029 79.0654410076971 -2.56864228761157 0.0106643642516396 HERC4 other 0.0161415145157911 1 1 3.3051263841287 -2.56864228761157 1.37597806252921e-06 99.7404710706047 30.8773359888696 3.23021620474507 0.00136551136419078 -191.295044919575 72.2524494082501 -2.64759252435437 0.00850814012392643 CAMK2G other 0.014107903075112 1 1 3.23021620474507 -2.64759252435437 0.0269470773611199 -82.7134980411128 221.048879574989 -0.374186461384224 0.708515758961413 -1173.54292818789 451.306088726686 -2.6003259373232 0.00974971314807625 ADIRF other 1 1 1 -0.374186461384224 -2.6003259373232 3.14891535806529e-09 633.232960682891 161.233463929969 3.92742886773141 0.00010532842897271 -1020.47388007272 329.12307044028 -3.10058446740786 0.00210421932394408 GLUD1 other 3.73618807234447e-05 1 1 3.92742886773141 -3.10058446740786 0.103888370655394 39.27286938447 60.3550175883599 0.650697671108693 0.515710060210719 -176.504235871923 116.833369163176 -1.51073479380199 0.131845942998887 ANKRD1 other 1 1 1 0.650697671108693 -1.51073479380199 0.00176934999184306 37.4610373016941 28.9650170718372 1.29332004910564 0.19683615140662 -134.066039323414 56.0695807505541 -2.39106548557684 0.0173788582750409 HTR7 other 1 1 1 1.29332004910564 -2.39106548557684 0.00285579196902857 -6.12677114683295 23.5238987189139 -0.260448798051781 0.79468564322888 -144.898553711121 45.5368327771656 -3.18200772592555 0.00160654187288573 RPP30 essential 1 1 1 -0.260448798051781 -3.18200772592555 0.000693738634160657 28.2348002064447 16.5613437898801 1.70486166851374 0.0891938171971217 -73.1412299414098 31.8183470490079 -2.29871243244518 0.0221674308362428 FRA10AC1 other 1 1 1 1.70486166851374 -2.29871243244518 0.793035547329017 -110.761770709795 166.87139964335 -0.66375526870706 0.507324880146942 -45.2891106074607 314.912164873699 -0.143815055939883 0.885737037029545 ADD3 other 1 1 1 -0.66375526870706 -0.143815055939883 0.400299259609469 26.0268110155226 32.984687022112 0.789057388905188 0.430662679389932 -42.6728817196213 63.9125167501007 -0.66767644100878 0.504821378965938 HABP2 other 1 1 1 0.789057388905188 -0.66767644100878 5.61674871094642e-24 229.213979566026 28.2583525929324 8.11137092341873 1.09963984895518e-14 -286.110393412438 65.5475079933446 -4.36493166821062 1.72169398841931e-05 DNAJB12 other 8.3341317373023e-20 0.252004349084934 1.57963264302411e-10 8.11137092341873 -4.36493166821062 4.80611603036563e-09 264.200002272272 114.874134822239 2.29990852754719 0.0220966691946592 -1092.84868200018 239.010997313223 -4.57237823483081 6.90057617385811e-06 EIF4EBP2 other 5.66256590697679e-05 0.102018118154318 1 2.29990852754719 -4.57237823483081 0.235952213972602 3.8176054132048 2.86521927229746 1.33239555175255 0.183678275431353 -2.70608871929793 5.96147180435876 -0.453929634846106 0.650187181015581 NPFFR1 other 1 1 1 1.33239555175255 -0.453929634846106 0.590058937623688 -52.2860461052134 61.8974385606793 -0.8447206753791 0.398897909640455 -106.358928267261 119.935080061416 -0.886804162825396 0.375850327008864 PLEKHS1 other 1 1 1 -0.8447206753791 -0.886804162825396 0.00582920819562116 25.7031714438407 28.8456323779569 0.891059384903013 0.373566783959436 -133.519150654091 54.8206765777379 -2.43556188995143 0.0154142874462536 TCF7L2 other 1 1 1 0.891059384903013 -2.43556188995143 0.00695562715379107 109.333789262661 319.159651417303 0.342567704837184 0.732148605281847 -1758.29831660005 646.473616018907 -2.71982997145026 0.00688828839289232 MKI67 other 1 1 1 0.342567704837184 -2.71982997145026 0.286889968727183 -56.5043320722253 35.6989143675435 -1.5828025326058 0.114454274398198 -47.5538213785423 65.6953133712352 -0.723854091536518 0.469684144696298 INA other 1 1 1 -1.5828025326058 -0.723854091536518 0.0242784404611498 38.0272562649155 23.674054178592 1.60628407699189 0.109229604415703 -63.2022863514701 47.8406748165008 -1.32109939071493 0.187442525543024 FUOM other 1 1 1 1.60628407699189 -1.32109939071493 0.509765417269929 -3.73124961034096 15.1603966804037 -0.246118204490254 0.805749514651805 -34.4884366535741 30.5920999736833 -1.12736414575144 0.260438471203698 LRRC27 other 1 1 1 -0.246118204490254 -1.12736414575144 0.0444006262508119 28.2319609990454 49.9256732445365 0.565479825595238 0.572160476827532 -197.960424309465 100.923151871641 -1.96149665005746 0.0507245920758036 MTG1 other 1 1 1 0.565479825595238 -1.96149665005746 0.0867436548185477 15.7490907957355 10.3126713796539 1.52715918271256 0.127715429080716 -15.9950305492634 20.8098957100452 -0.768626175360522 0.44268570680081 NKX6-2 other 1 1 1 1.52715918271256 -0.768626175360522 0.0814853541476091 -0.856669328140453 12.7214155152893 -0.0673407237670102 0.946354150368999 -52.9136738828794 25.7131063889986 -2.05784836271353 0.04044597527542 PAOX other 1 1 1 -0.0673407237670102 -2.05784836271353 0.375097434671866 -131.881065800945 211.017176897595 -0.62497787023729 0.532430972883213 -553.545005903696 394.698354910319 -1.40245075515825 0.161750056484505 GSTO1 other 1 1 1 -0.62497787023729 -1.40245075515825 0.0439955100503792 5.67482683848695 8.10892116094714 0.699825134053236 0.484546535295746 -27.906596721457 14.924685767874 -1.86982809256373 0.0624235231359918 TAF5 other 1 1 1 0.699825134053236 -1.86982809256373 1.02089667650984e-11 383.859285310786 73.9764979225174 5.18893562267355 3.76987093288578e-07 -333.762390436795 135.932228576515 -2.45535877644294 0.0146076210256831 PPRC1 essential 1.3125668569887e-07 1 0.00458190113182938 5.18893562267355 -2.45535877644294 2.96419560231892e-07 437.540293004295 134.412585640176 3.2552033049613 0.00125439670825722 -680.00409258859 251.412833833739 -2.70473102832245 0.00720182338887365 ITPRIP other 0.00318502817469168 1 1 3.2552033049613 -2.70473102832245 8.28682201506367e-05 71.3679439523792 61.3228952451685 1.16380584555003 0.24536970617969 -374.751837431018 112.850121392641 -3.32079250608105 0.00100137368235099 CNNM2 other 0.719710492008279 1 1 1.16380584555003 -3.32079250608105 2.14866871738702e-08 358.297801308426 85.8434396181876 4.17385187385377 3.86708084436042e-05 -349.233594118837 157.997141186322 -2.21037919734886 0.0277882851240883 PDCD11 essential 0.000245592834397336 1 0.416523277746061 4.17385187385377 -2.21037919734886 0.880078504949054 75.1916277765757 181.469129983584 0.414349414599484 0.678895836903476 -32.3759470740911 367.574673475572 -0.0880799179333085 0.929868251896687 ADAM12 other 1 1 1 0.414349414599484 -0.0880799179333085 0.000285495468519312 47.804711045227 41.9943854672918 1.13835958100782 0.2558218944253 -250.734630772366 81.7485148076525 -3.06714600702317 0.00234556517233697 RGS10 other 1 1 1 1.13835958100782 -3.06714600702317 1.53083692293842e-14 95.4331428478557 33.0029840334313 2.8916519412664 0.00409790196642055 -399.966466971229 69.1841736094522 -5.78118442563263 1.7804854097073e-08 BTBD10 other 2.0879084791957e-10 0.000270188660923083 1 2.8916519412664 -5.78118442563263 0.00215265537471694 455.143281139391 291.682181565447 1.56040824536025 0.119661184387452 -1187.83329003683 587.65298877629 -2.02131753385673 0.0440869799972655 ADM other 1 1 1 1.56040824536025 -2.02131753385673 0.280837985526382 5.64064852527339 3.53367732507412 1.59625455478029 0.111422108430699 4.99728856343554 7.42310252139893 0.673207536744862 0.501302685556447 GAS2 other 1 1 1 1.59625455478029 0.673207536744862 0.262222622507759 6.97775144029911 6.96696152897584 1.00154872554964 0.317327903202177 23.8317898833576 14.8005915659174 1.6101917127581 0.108354444622594 SLC5A12 other 1 1 1 1.00154872554964 1.6101917127581 9.6557552509848e-10 95.9667175418189 33.0909033203811 2.90009361825767 0.00399111907352695 -288.506543373342 70.8617964297095 -4.07139753589965 5.90753212597326e-05 LIN7C other 1.16786359760661e-05 0.849857571642513 1 2.90009361825767 -4.07139753589965 0.000524143152165053 13.1276452535253 6.11281917542952 2.14755988632738 0.0325042240618732 -27.5172145438783 13.50806144155 -2.037095749301 0.0424682148544897 IMMP1L other 1 1 1 2.14755988632738 -2.037095749301 0.0547879869269623 4.96924357515732 10.9509172974562 0.453774185319765 0.650299917686689 -44.0190458662383 22.9117687068997 -1.92124171771088 0.0555921453654712 SAA4 other 1 1 1 0.453774185319765 -1.92124171771088 1.45751809072059e-14 86.3119406917479 27.3423923932968 3.15670770319673 0.0017474759334858 -279.222901089318 54.3364138836711 -5.13878044449357 4.81987511941339e-07 PGAP2 other 1.98892918659732e-10 0.0072486101920858 1 3.15670770319673 -5.13878044449357 2.00134877552995e-09 81.8078782357811 16.1083103140646 5.07861325246215 6.54275257481404e-07 -147.027911358359 59.0521179738204 -2.48979911988155 0.0133002499656332 TUT1 essential 2.39101138212563e-05 1 0.00786308004441151 5.07861325246215 -2.48979911988155 0.271406775654395 -51.1600774063671 38.6498730418313 -1.32368034821216 0.186587678445497 -179.939501977981 142.728557413296 -1.26071127768029 0.208363992119665 SCGB1A1 other 1 1 1 -1.32368034821216 -1.26071127768029 0.111332645641037 41.8247168034658 83.4959915764342 0.500918858663754 0.616772603062618 -211.655370597134 152.588483326007 -1.38709924880064 0.166376858653457 SYT8 other 1 1 1 0.500918858663754 -1.38709924880064 0.0159712940131098 -4.31665223308178 2.7239346578446 -1.58471210777775 0.114019465830218 -15.6651401374604 5.42553926184737 -2.88729642924498 0.00415015748693489 ZNF214 other 1 1 1 -1.58471210777775 -2.88729642924498 0.234585584121836 6.29821848323644 5.38610835351629 1.16934492770178 0.243134958028126 -5.59297914390301 10.7280628984287 -0.521341009728998 0.602489845208413 ZNF215 other 1 1 1 1.16934492770178 -0.521341009728998 4.31387859922649e-07 222.522085913469 68.6853002068889 3.23973376025444 0.00132676586242993 -404.309530159309 163.096131002647 -2.47896456938483 0.0137097877347934 HSD17B12 other 0.00458177046023846 1 1 3.23973376025444 -2.47896456938483 9.69855508446405e-11 64.7040997703381 11.2931556548521 5.7294968517093 2.34267724777813e-08 -44.4627072530671 29.7452553463873 -1.49478317584748 0.135965810973812 APIP other 1.21348321216814e-06 1 0.000298995897133923 5.7294968517093 -1.49478317584748 0.833890198468066 -16.7423066249722 41.0611493352352 -0.407740818170555 0.683740069704512 -61.3259401254928 107.803774630597 -0.568866353109006 0.569850918149356 PAMR1 other 1 1 1 -0.407740818170555 -0.568866353109006 1.47328010148306e-07 174.825650206953 50.4638565214241 3.46437355878126 0.000605576156073414 -305.282356771544 124.465718380419 -2.45274249603793 0.0147225824156498 DGKZ other 0.00161073713495143 1 1 3.46437355878126 -2.45274249603793 1.6402365782511e-21 961.711539626861 110.572799026039 8.69754178331314 1.80904049731248e-16 -713.047333858507 294.106526629018 -2.42445260236586 0.0158850194982029 EIF3M essential 2.40458682371611e-17 1 2.63450567623617e-12 8.69754178331314 -2.42445260236586 8.64740735554313e-14 1522.0946178893 243.961483959318 6.23907755104128 1.41256938446356e-09 -4476.23771787014 1081.83665236536 -4.13762808653519 4.50436488316606e-05 TNKS1BP1 other 1.16402750412966e-09 0.650835681968664 1.87179569135266e-05 6.23907755104128 -4.13762808653519 0.901301503974514 -24.2535215399859 245.130659307293 -0.0989411998014577 0.921247889534035 -412.865125277427 906.11700849532 -0.455642175796945 0.648961239107184 SERPING1 other 1 1 1 -0.0989411998014577 -0.455642175796945 7.6648875194444e-15 808.807069852357 146.086475986572 5.53649517787467 6.49487137195583e-08 -2763.91238407694 559.727163148903 -4.9379636473738 1.28097169919561e-06 SSRP1 essential 1.05139262104219e-10 0.0191633366199663 0.00081452181875698 5.53649517787467 -4.9379636473738 0.975385224838724 3.17932340095722 14.673397835032 0.216672609623297 0.828604198851626 5.82953408372217 56.0393347254201 0.104025754629057 0.917215321356873 SLC43A1 other 1 1 1 0.216672609623297 0.104025754629057 0.544668997608537 -5.82771499587207 27.2455938120533 -0.21389568662269 0.830765053607572 -76.7481336519269 71.9696986056631 -1.06639509597568 0.287051493117747 PTPRJ other 1 1 1 -0.21389568662269 -1.06639509597568 9.79696906131296e-08 63.3705434245605 21.4473569851361 2.95470175968437 0.00336484930458213 -166.475740126788 53.7616331402777 -3.09655288358542 0.00213331376545604 C11orf49 other 0.0010819772631314 1 1 2.95470175968437 -3.09655288358542 5.91638740241161e-22 348.470192354754 57.5538835184357 6.05467730501855 3.97551368180077e-09 -737.505481865794 145.906763655477 -5.05463532593481 7.3031348540679e-07 ARFGAP2 other 8.69353964910362e-18 0.0109568932215581 5.20235720400449e-05 6.05467730501855 -5.05463532593481 1.43845082227315e-14 370.958029927184 67.014710680672 5.5354716324124 6.50085237496927e-08 -503.280267264144 167.417516709839 -3.00613864758494 0.00285658275941697 CELF1 other 1.96334152732062e-10 1 0.000815206887821147 5.5354716324124 -3.00613864758494 1.30535390965725e-24 118.195247210407 15.6474109326328 7.55366160697616 4.65650185841968e-13 -120.194717040716 39.2220036083145 -3.0644716226388 0.00236965099041157 HIKESHI other 1.94249715296095e-20 1 6.55868286758412e-09 7.55366160697616 -3.0644716226388 5.29268795289175e-07 459.04865638699 234.066985586017 1.96118497975143 0.0507409345872137 -1635.4383054304 548.956848283029 -2.97917461189447 0.00311566498548601 SESN3 other 0.00558590286548195 1 1 1.96118497975143 -2.97917461189447 4.49283331048019e-20 508.004586410951 96.362188811535 5.27182490016396 2.51306357994949e-07 -872.35607013685 225.4314744433 -3.86971727125115 0.00013245323805804 ENDOD1 other 6.52494181681039e-16 1 0.00307925680451211 5.27182490016396 -3.86971727125115 4.63256565391127e-08 46.9268088252252 13.7440095771591 3.41434634207559 0.000723019443944139 -62.2305101184903 32.0314985062527 -1.94279109690552 0.0529322048911793 CCDC82 other 0.000519773866368845 1 1 3.41434634207559 -1.94279109690552 0.770166909405115 3.58063599994193 11.4040019025292 0.313980656136845 0.753743562204152 -15.0319104422413 35.4555702584753 -0.423964706607648 0.671880924213244 KLHL35 other 1 1 1 0.313980656136845 -0.423964706607648 1.54423949212108e-06 139.948045550414 41.1311930121308 3.40247960979735 0.000753981709087714 -224.063856476187 124.50231461166 -1.79967623232606 0.0728685929345046 TENM4 other 0.0157605082565878 1 1 3.40247960979735 -1.79967623232606 3.09496513911465e-10 2090.45483790194 344.384393209707 6.07012071139064 3.67035040190592e-09 99.3543665715864 1070.6271111659 0.0928001593975989 0.926121317068503 SERPINH1 other 3.8170205060701e-06 1 4.80889309657713e-05 6.07012071139064 0.0928001593975989 0.00625515449967094 11.1053808700183 25.0999211273093 0.442446843306428 0.658471469625395 -197.748253557342 76.6821398917278 -2.57880458000461 0.0103707004392617 CAPN5 other 1 1 1 0.442446843306428 -2.57880458000461 1.02693409716213e-36 131.403151747504 12.0588707941694 10.8968040200778 1.09707313625027e-23 -141.935411696345 39.0512311102796 -3.63459506040983 0.00032487694183834 INTS4 essential 1.56473948384594e-32 1 1.64769414333428e-19 10.8968040200778 -3.63459506040983 1.0936248597299e-13 348.972953133019 85.0769547107379 4.10185054600895 5.22318073541071e-05 -1152.8190104909 271.938981041466 -4.23925619665067 2.95002264824766e-05 PAK1 other 1.46895691158920e-09 0.428874292602245 0.556320980128595 4.10185054600895 -4.23925619665067 1.10463039257203e-13 4839.93919679243 862.547225439024 5.61121646913764 4.40475482365059e-08 -6654.72063384573 2681.6992854082 -2.48153127013746 0.0136032084460471 RPS3 essential 1.48351861722424e-09 1 0.000556100296485887 5.61121646913764 -2.48153127013746 1.00364815792918e-07 101.495786647776 29.7337877395402 3.4134832580649 0.000725230725773746 -80.1971616837662 54.3242341540679 -1.47626861073311 0.140870739378098 ZC3H12C other 0.00110762610709064 1 1 3.4134832580649 -1.47626861073311 1.45873745643795e-07 8.58542611665268 11.0988925102808 0.773538991273233 0.439776304307785 -78.4290539185604 20.3405937583823 -3.85578979896985 0.000139535887949491 TTC12 other 0.00159542115610618 1 1 0.773538991273233 -3.85578979896985 0.0689055340813969 129.656416963463 56.9155281668665 2.27804996526312 0.0233846768541665 116.337994728381 104.164612705957 1.11686677179694 0.264891799289991 NCAM1 other 1 1 1 2.27804996526312 1.11686677179694 1.57786964738199e-05 20.6921347281063 11.1471500025292 1.85627130911591 0.0643426176144812 -44.5330498816961 20.4821132550602 -2.17424097441186 0.0304264350852861 C11orf52 other 0.147972615531483 1 1 1.85627130911591 -2.17424097441186 1.54390398408963e-09 80.4441753806638 22.8902943676615 3.51433555587263 0.000505242462257934 -87.5641854705561 42.030372518033 -2.08335496986107 0.0380223490534031 NPAT essential 1.85160404811869e-05 1 1 3.51433555587263 -2.08335496986107 3.8248186437902e-05 144.79836727206 44.3422804289664 3.26546956699752 0.00121276837721821 -34.5438451660251 81.419772712121 -0.424268504017607 0.671658694976251 ATM ts 0.345610612652883 1 1 3.26546956699752 -0.424268504017607 4.57051886327416e-33 238.802951045305 31.0282769617684 7.69630074333637 1.7925773229844e-13 -244.237664787842 59.5792084616988 -4.0993774689849 5.26864955607418e-05 AASDHPPT essential 6.93484827124588e-29 0.759528520003653 2.54151612852728e-09 7.69630074333637 -4.0993774689849 0.155913957272576 -12.3679036187859 43.5174500442459 -0.284205614212482 0.776447577282755 -131.972024122663 79.4800306795276 -1.66044254128171 0.0978633220326482 GLB1L2 other 1 1 1 -0.284205614212482 -1.66044254128171 9.70926789871878e-13 55.4961767204762 8.10053877341132 6.85092415119759 3.8252656531516e-11 -53.1967307419993 31.5352147894886 -1.68689926791718 0.0926064704256583 SLX4IP other 1.27977860173012e-08 1 5.23717120572985e-07 6.85092415119759 -1.68689926791718 5.08388080493364e-34 596.891726138029 47.6845646853449 12.5175039360583 4.35489063879988e-29 -248.140677597762 197.524797486141 -1.25625076322466 0.210025778602246 LAMTOR1 other 7.7229233307747e-30 1 6.60593360999553e-25 12.5175039360583 -1.25625076322466 1.10723967324458e-07 43.0692513049368 7.60990161206851 5.65963313331587 3.40444455569707e-08 33.9014658717397 26.4893494740544 1.27981496506531 0.201549006145968 P4HA3 other 0.00121851726040566 1 0.00043154739188016 5.65963313331587 1.27981496506531 4.67173082803564e-14 1028.82693632557 335.239761972998 3.06892872811561 0.00233439500418942 -2428.99567923516 612.216179954365 -3.9675457114123 8.99040323449883e-05 ST14 other 6.31197552175895e-10 1 1 3.06892872811561 -3.9675457114123 1.22803166371118e-17 1830.65191832869 261.255023179262 7.00714534040776 1.4514743433023e-11 -203.43585299237 492.854810058636 -0.412770351106376 0.68005216363141 HYOU1 essential 1.74417337196899e-13 1 2.00201856171686e-07 7.00714534040776 -0.412770351106376 0.432313322811247 5.15256903886368 4.38819465265895 1.17418880580914 0.241192503308139 -3.25785324584808 16.213628966213 -0.200933008436113 0.84087860928533 ADAM33 other 1 1 1 1.17418880580914 -0.200933008436113 1.50125017729367e-18 146.366337508729 16.0724478214695 9.10666123384229 9.79164092866532e-18 -66.450223993943 65.3782805642645 -1.01639601746064 0.310215947831843 KAT14 other 2.15099125402637e-14 1 1.43584622577948e-13 9.10666123384229 -1.01639601746064 3.51757520771335e-14 236.208749701942 31.3524996530286 7.53396865691775 5.0844090299894e-13 -227.987729590691 146.132434277915 -1.56014460935553 0.119714111722167 TKFC other 4.7638521038062e-10 1 7.15935635512807e-09 7.53396865691775 -1.56014460935553 6.48387882780968e-08 238.609449125396 98.0559061846366 2.43340211120074 0.0155171414641394 -1604.14997607714 359.467183531303 -4.46257697383786 1.13116098377253e-05 MTA2 other 0.000722304101417998 0.166258041394887 1 2.43340211120074 -4.46257697383786 4.8859097567016e-27 165.409042057501 14.043105504959 11.7786654810142 7.57623458720657e-27 -6.93644411320544 65.4542130602659 -0.105973989891511 0.915669389190361 TMEM138 other 7.33326195383343e-23 1 1.1456024319315e-22 11.7786654810142 -0.105973989891511 0.0363746151293318 4.68689342477181 4.04283774281189 1.1593078235962 0.247214371384606 -27.9397779093311 14.8208053286069 -1.8851727210398 0.0603326523357091 ROM1 other 1 1 1 1.1593078235962 -1.8851727210398 2.50358825819147e-08 126.325023855284 29.2333929559585 4.32125768109089 2.08651312677779e-05 -307.447183184256 107.167898802088 -2.86883653240259 0.00439989328785876 EML3 other 0.000285183738490591 1 0.229039045213795 4.32125768109089 -2.86883653240259 2.03276930101821e-05 108.38785745893 41.4221885691558 2.6166617748353 0.0093089135134752 -445.535411189397 148.513866712318 -2.99995832747679 0.00291630671331788 INCENP essential 0.18860033574847 1 1 2.6166617748353 -2.99995832747679 0.000379346960032474 232.540212408788 83.6618473021369 2.77952519466838 0.00576785312006095 -368.436561452749 185.508661223903 -1.98608819136513 0.0478818086424814 PLCH2 other 1 1 1 2.77952519466838 -1.98608819136513 3.34314303339261e-15 304.994712718618 42.8499502675543 7.11773784600068 7.2527672042695e-12 -610.046652252395 199.721477093787 -3.05448698422115 0.00244387660104191 CPSF7 other 4.60718541431836e-11 1 1.00552364519992e-07 7.11773784600068 -3.05448698422115 0.277823856054702 -3.69597991948702 2.30491611645517 -1.60352035941821 0.109806334879637 -4.23242557321748 8.12934241988632 -0.520635662100289 0.602980645510968 MS4A2 other 1 1 1 -1.60352035941821 -0.520635662100289 0.00372789220003436 133.861793430809 42.5182551833481 3.14833694029934 0.00180028354689871 -40.8150884334988 155.869422191093 -0.261854364119347 0.793605960813084 B3GAT3 other 1 1 1 3.14833694029934 -0.261854364119347 2.23754013228054e-39 771.963426860289 102.66667779183 7.51912347281308 5.63638151485155e-13 -1084.35806566004 190.113623272244 -5.70373678117337 2.67448368225391e-08 EI24 other 3.4160525199527e-35 0.000405585450413805 7.93151606769911e-09 7.51912347281308 -5.70373678117337 1.3451830490432e-05 11.2420880049383 4.86187616418055 2.31229418958948 0.021397805635434 -16.3761508455952 9.00300772707849 -1.81896443300169 0.0698543176105588 CCDC15 other 0.126985279829678 1 1 2.31229418958948 -1.81896443300169 3.51562967771352e-09 102.560572651331 30.0289299801162 3.41539218078174 0.000719262553014275 -115.151050870939 55.6062473657125 -2.07082938205865 0.0391787089499503 CHEK1 essential 4.16426335325167e-05 1 1 3.41539218078174 -2.07082938205865 1.4204071342556e-11 383.77953964717 100.95207916353 3.80160114409822 0.000172213549312646 -463.44392687707 186.938605197297 -2.47912370153797 0.013686959705749 FEZ1 other 1.81939949826799e-07 1 1 3.80160114409822 -2.47912370153797 0.37030292651403 12.6811801995458 23.8006536013762 0.532808065355504 0.594537407247268 59.5026989873875 44.0730000203171 1.35009413836039 0.177942925870268 ESAM other 1 1 1 0.532808065355504 1.35009413836039 0.393842222905416 -2.40744922861777 10.3904300380795 -0.231698709273321 0.816920589349534 17.2592524964504 19.2702937311326 0.895640343487176 0.371120211032681 KIRREL3 other 1 1 1 -0.231698709273321 0.895640343487176 4.32443718410712e-10 170.166926706311 286.710367172478 0.593515080687481 0.553257082402322 -2632.54154902785 542.112687304789 -4.85607810087604 1.87878620756381e-06 MPZL2 other 5.30348976258897e-06 0.0280521568651353 1 0.593515080687481 -4.85607810087604 4.61989075316294e-09 26.8774674067189 4.36463240605888 6.15801398747997 2.21394002257941e-09 21.4334434278393 8.2526579909918 2.59715638903672 0.00983543623737053 SCN2B other 5.44916114335569e-05 1 2.91930131377322e-05 6.15801398747997 2.59715638903672 1.12924321971632e-11 180.719018945114 36.1142897571169 5.00408619858019 9.27997209255828e-07 -64.4552260667487 66.7251384784528 -0.965981150980493 0.334783073097939 SIDT2 other 1.45028706708166e-07 1 0.0110812146757238 5.00408619858019 -0.965981150980493 2.84468449457963e-07 98.3371009382717 21.3828005352214 4.59888781996972 6.13287258698603e-06 16.8506982885979 40.4306533264551 0.416780262058538 0.677119451143999 TMEM25 other 0.00305974264236985 1 0.0698534187657709 4.59888781996972 0.416780262058538 0.0920039346512097 1009.0848602704 467.669216924291 2.15768928925198 0.0316958341524108 936.420819082175 864.07052364178 1.08373193328649 0.279299534481453 TAGLN other 1 1 1 2.15768928925198 1.08373193328649 0.0273050333540572 74.0962305131286 28.7706335721892 2.57541184580491 0.0104621087471494 -17.2987357536264 128.378722129111 -0.134747686117557 0.892896347527829 JPH2 other 1 1 1 2.57541184580491 -0.134747686117557 0.385746214088405 5.11181033409598 3.72726527046247 1.37146405290915 0.1712286336183 -0.0608724643031346 23.0671125625834 -0.0026389286538565 0.997896150382171 DUSP15 other 1 1 1 1.37146405290915 -0.0026389286538565 0.000368962301348628 89.3925770389199 23.2193714495285 3.84991373402294 0.000143276275828057 -102.921327067425 148.571846716614 -0.69273775174739 0.488987790784695 COMMD7 other 1 1 1 3.84991373402294 -0.69273775174739 0.972697372561796 -1.38506670405833 9.38921442951625 -0.147516782629247 0.882818210990571 -9.97362151623197 47.4383082670094 -0.210244038638453 0.833612705232429 KIAA1755 other 1 1 1 -0.147516782629247 -0.210244038638453 0.000193910612635367 88.5610671339091 22.9929792410219 3.85165689950726 0.000142053137355349 -101.751983521786 123.117125176075 -0.826464907918096 0.409163999925986 DSN1 essential 1 1 1 3.85165689950726 -0.826464907918096 1.33723352655202e-05 384.197328299694 79.7692098138816 4.8163612150115 2.27188802491813e-06 527.984753884128 427.12845894849 1.23612637561994 0.21732963401809 SOGA1 other 0.126274961912307 1 0.026556099123268 4.8163612150115 1.23612637561994 5.50975366012539e-08 9.55818546447653 1.69011239737298 5.65535492156217 3.49071553697236e-08 -6.4035288459035 9.23564698898442 -0.693349242726703 0.488601322059078 CNBD2 other 0.00061604555673862 1 0.000442343472845138 5.65535492156217 -0.693349242726703 0.0253932456312815 7.28733654456519 3.21465523436704 2.26691076127175 0.0240626751796834 -13.5462099249468 14.6145552449063 -0.926898540389598 0.354677757840861 CDH22 other 1 1 1 2.26691076127175 -0.926898540389598 9.53625036523912e-19 273.779524865584 29.504338950735 9.27929703230187 2.64701207346099e-18 -108.851825062323 134.267719645524 -0.810707334195432 0.418136282638291 LSM14B other 1.36883337742642e-14 1 3.89746057696396e-14 9.27929703230187 -0.810707334195432 2.03289476136815e-17 269.106881331701 30.554828732525 8.80734379784764 8.2495660560569e-17 -140.756581921953 139.368823430366 -1.00995745287525 0.313278724044383 YTHDF1 other 2.88061187685868e-13 1 1.20336420059702e-12 8.80734379784764 -1.00995745287525 0.332935473214688 16.927951988329 13.0417735628059 1.29797928991853 0.195238062520634 -26.2342201489184 60.3265903880387 -0.434869930161345 0.66395273643038 CABLES2 other 1 1 1 1.29797928991853 -0.434869930161345 1.78564991575008e-42 381.907788519492 22.883338750299 16.6893385920139 7.31543139351733e-43 -61.0819823766571 334.990237598988 -0.18233958939955 0.855459977445617 ORAOV1 essential 2.73025872118187e-38 1 1.11940731183602e-38 16.6893385920139 -0.18233958939955 2.74089893941693e-06 69.1142203271936 15.3146035341053 4.51296177359587 9.0491902374339e-06 -74.7906659799253 60.421854271961 -1.23780818846257 0.216711929817717 TRPT1 other 0.0274144711920482 1 0.10194817721493 4.51296177359587 -1.23780818846257 9.79924779620879e-06 133.141855476321 33.6794098186093 3.95321225025608 9.53176905151217e-05 -231.219734259373 132.8779022907 -1.74009169525816 0.0828226563453017 NUDT22 other 0.0936024149493863 1 0.989921238630615 3.95321225025608 -1.74009169525816 0.0305373367930133 -60.2591449006791 31.6546058059912 -1.90364540534806 0.0578704819266649 160.630649023784 124.889291112668 1.28618432847755 0.199326311587381 FERMT3 other 1 1 1 -1.90364540534806 1.28618432847755 1.56599723451079e-14 608.158962167931 86.1739633283661 7.05734004423749 1.07990215828304e-11 -864.742166046854 341.172464182086 -2.53461887119159 0.0117392988009402 PLCB3 other 2.13523722925546e-10 1 1.49361267512127e-07 7.05734004423749 -2.53461887119159 3.21363158065077e-13 292.665862049832 44.5566081420563 6.56840532198385 2.09203184276691e-10 -567.236437960426 192.356548769805 -2.94888030372828 0.00342712543891646 MRPL49 other 4.27541545489779e-09 1 2.82487059728816e-06 6.56840532198385 -2.94888030372828 0.00180527588764065 47.287494010962 17.2921716265981 2.73461859112168 0.00659992680112485 -129.536914412478 76.5206365631407 -1.69283634102535 0.0914784826856818 CDC42EP2 other 1 1 1 2.73461859112168 -1.69283634102535 2.73005880982444e-09 1280.42794660303 221.066626861299 5.79204543346287 1.67507205435906e-08 -1518.14356886943 954.325796299285 -1.59080219224559 0.112650822900404 FAU essential 3.2484969778101e-05 1 0.000214995498176986 5.79204543346287 -1.59080219224559 0.405174709174927 27.2706380354527 36.142375695863 0.754533632900456 0.451089014076536 -144.490572076858 156.023557041665 -0.926081771346061 0.355107973326791 TM7SF2 other 1 1 1 0.754533632900456 -0.926081771346061 1.03304454659376e-15 512.69237755933 63.3379296907374 8.09455534878822 1.24374043175175e-14 -431.850406711154 273.424446947323 -1.5794140265532 0.115238405691177 VPS51 essential 1.43520878858271e-11 1 1.78588688595234e-10 8.09455534878822 -1.5794140265532 0.00353276135757785 36.6635023732199 13.4190163979754 2.73220490130347 0.0066450414093404 -56.4240077517619 48.0548891463681 -1.17415748436965 0.241216070416019 TBX6 other 1 1 1 2.73220490130347 -1.17415748436965 1.14087465814749e-06 353.360354733949 95.9737524638431 3.68184368811746 0.000272238132049407 -930.799850869423 343.691959144398 -2.70823865995177 0.00713251876833033 PPP4C essential 0.0117635586001588 1 1 3.68184368811746 -2.70823865995177 0.000221148235487549 3436.28369574433 1354.74229254591 2.53648514160333 0.0116766515392354 -12107.0189234961 4905.49563593446 -2.4680521239909 0.0141125998302716 ALDOA essential 1 1 1 2.53648514160333 -2.4680521239909 0.0606224339385189 8.19563312444462 3.8121518095113 2.14987060693558 0.0323217412625589 21.6717254271076 13.8037279621162 1.56999076529071 0.117414846825387 FAM57B other 1 1 1 2.14987060693558 1.56999076529071 0.202345609380853 21.576597912424 15.9609515637205 1.35183656352093 0.177391357382484 -43.8340293558453 57.7942968725463 -0.758449046495236 0.448745720932245 DOC2A other 1 1 1 1.35183656352093 -0.758449046495236 0.723300220101556 -4.11522470384228 29.1620227750629 -0.14111588676768 0.887868025109573 -84.5856924973361 105.595120374707 -0.801037890739471 0.423709685963944 HIRIP3 other 1 1 1 -0.14111588676768 -0.801037890739471 0.0128697135857136 75.4468280177119 39.8694833849385 1.89234526289883 0.0593559829253375 -242.55290590423 144.366628123961 -1.68011755248562 0.0939195828869966 TAOK2 other 1 1 1 1.89234526289883 -1.68011755248562 0.0936084046161207 -17.5922922163874 75.7724979581151 -0.232172525526504 0.816553828949204 -590.494932226909 274.370749405677 -2.15217888024142 0.0321379688906447 TMEM219 other 1 1 1 -0.232172525526504 -2.15217888024142 1.73462148815538e-06 566.301308293415 108.125882204646 5.23742601444488 2.98411676455055e-07 51.5174766713418 504.659333769588 0.10208366956483 0.918755214862293 HMGA2 other 0.0176168158337061 1 0.00364360656951622 5.23742601444488 0.10208366956483 0.534165656198311 38.1794242143125 60.9987186349653 0.625905347992466 0.531834624586875 -616.197751228256 794.444400771331 -0.775633575653609 0.438552879069032 MMP3 other 1 1 1 0.625905347992466 -0.775633575653609 0.655687056654441 0.325205993647421 2.28334269538498 0.14242539865116 0.886836822775951 -5.78280973718802 7.71709244022211 -0.749350844502982 0.45421585687676 CNTN5 other 1 1 1 0.14242539865116 -0.749350844502982 1.25086822152827e-28 222.832111396333 17.726723933193 12.5704056900826 1.03674276243236e-29 166.947704482078 91.7608563279204 1.81937823123039 0.0697910435746932 CLEC1A other 1.88443297573234e-24 1 1.5739828619248e-25 12.5704056900826 1.81937823123039 0.559226348458283 1.27359301406125 3.8241206116142 0.333042062060813 0.73932199586394 -5.68402458625834 7.65244064220242 -0.742772776950603 0.458167594748928 MKX other 1 1 1 0.333042062060813 -0.742772776950603 0.00188559171802111 1.05944236256732 56.0249129902289 0.0189102009449276 0.984924601015829 -351.354897405248 112.111349166184 -3.13398152835027 0.0018852323741803 MPP7 other 1 1 1 0.0189102009449276 -3.13398152835027 0.0657141367195694 939.680805476137 687.618600031917 1.36657269805168 0.172740125162973 -1301.56029755863 1354.26145041261 -0.961084949410672 0.337251309911324 ITGB1 other 1 1 1 1.36657269805168 -0.961084949410672 0.000126367867084391 47.0231209202679 11.0819989236138 4.24319847388451 2.90882554749506e-05 20.6432276793551 38.1232293469527 0.541486858090767 0.588558498728135 CTF1 other 1 1 0.316102072246288 4.24319847388451 0.541486858090767 4.33838034729845e-25 213.839438790621 29.4772000682535 7.25440131001189 3.15547093255093e-12 -207.771895812002 68.9595032637021 -3.01295522703346 0.00279697472519629 CWC15 other 6.4702604499609e-21 1 4.398726479976e-08 7.25440131001189 -3.01295522703346 0.968834466909005 0.0282715229905651 6.61855307849338 0.00427155643465818 0.996594522579567 -6.79733419384605 27.0112673121217 -0.251648103559941 0.801478217395026 FCGR1A other 1 1 1 0.00427155643465818 -0.251648103559941 0.123091526779171 -64.5020361741126 96.7960222667229 -0.666370731602755 0.505661908167013 -456.557889622579 222.349533527459 -2.05333414637542 0.0408656122108019 ARID5B other 1 1 1 -0.666370731602755 -2.05333414637542 0.0894607790858096 17.6157971101284 8.98849612434025 1.95981584310038 0.0508849731197709 -2.04305442174727 23.6057399473541 -0.086549052319636 0.931084093921255 CDH8 other 1 1 1 1.95981584310038 -0.086549052319636 1.05782934988885e-07 42.3107757487459 7.50298762980524 5.63919039139402 3.81078094792591e-08 -1.4940378491189 18.3978818638314 -0.0812070574306734 0.935329022985547 DCUN1D2 other 0.00116562216064252 1 0.000482216221150545 5.63919039139402 -0.0812070574306734 2.82557078662396e-11 202.463689325156 30.5603849810315 6.62503726477341 1.50849556398612e-10 -99.6938929187119 74.9363294110641 -1.33038132107912 0.184358057920748 TMCO3 other 3.59582138305766e-07 1 2.0429555423064e-06 6.62503726477341 -1.33038132107912 2.92546710083425e-16 28.5904123075964 10.0823699905239 2.83568370675423 0.00486482742712108 -89.5077063544531 18.6700878152149 -4.79417704085516 2.50936658387731e-06 TMEM218 other 4.09155828722678e-12 0.0373895620997719 1 2.83568370675423 -4.79417704085516 1.52898160594573e-07 22.8168247216265 6.97220394885784 3.27254120633753 0.00118266776000539 -20.4052137686028 12.930785112402 -1.57803362991718 0.115548971222573 TIRAP other 0.00166980081185333 1 1 3.27254120633753 -1.57803362991718 0.000183495969866921 0.442315057596525 5.33722637427884 0.0828735801292091 0.934005894789576 -31.6755632341615 8.65388559476236 -3.6602706249471 0.000296372865222675 EEF1AKMT1 other 1 1 1 0.0828735801292091 -3.6602706249471 1.79089564901836e-07 128.127993989924 28.4155520472232 4.50907987910954 9.26581801458325e-06 -43.6741469943309 46.073544437566 -0.94792244719773 0.343912070012338 LATS2 other 0.00194795719743726 1 0.104305313390164 4.50907987910954 -0.94792244719773 3.70932239761056e-18 212.091038941515 63.6336575065943 3.33300091888537 0.000963579221200378 -650.478311532099 102.9930755527 -6.31574800578959 9.34917409929145e-10 SAP18 essential 5.29579958706859e-14 1.42687095103386e-05 1 3.33300091888537 -6.31574800578959 0.0514191846586528 49.6401993488379 20.2839835456053 2.44726087640674 0.0149353457140123 42.4623869063344 42.0347137739657 1.01017428439428 0.313179804828044 ADGRL3 other 1 1 1 2.44726087640674 1.01017428439428 8.37981375545792e-20 18.8530215190966 5.91296505121545 3.18842092855279 0.00157473614351472 -64.3231569904511 10.4768274641752 -6.13956440634338 2.49632226013123e-09 KIAA1328 other 1.21440260944096e-15 3.804644756666e-05 1 3.18842092855279 -6.13956440634338 0.486501617484997 5.4087305114278 8.75546406840504 0.617754863610913 0.537180467042231 -11.633816414589 16.1594951935683 -0.719936871494563 0.472094334198532 FAM124A other 1 1 1 0.617754863610913 -0.719936871494563 0.400956714728393 -15.1648957157772 11.4181410608872 -1.32814051209479 0.185096253128394 -14.5719820697061 29.2305952582151 -0.498518143095656 0.618467902111214 HNMT other 1 1 1 -1.32814051209479 -0.498518143095656 0.0671914940409827 118.636031596806 77.7443829405051 1.52597560247656 0.128006767014891 -310.785711198281 204.145334759756 -1.5223747903131 0.128905841947113 LYPD1 other 1 1 1 1.52597560247656 -1.5223747903131 0.490123810839613 16.5564258749256 23.3445907977621 0.709218937198621 0.47871155297642 -51.2637330571704 61.4225951336807 -0.834607084666474 0.404569477403585 LYPD6B other 1 1 1 0.709218937198621 -0.834607084666474 0.443512098911747 -25.102239554537 20.6241568251447 -1.2171280390931 0.224452346013882 -33.7560026504935 38.920976802389 -0.867295875483307 0.386429802854921 ADRA2A other 1 1 1 -1.2171280390931 -0.867295875483307 0.188362546781749 -1.37768756430843 9.54986841416284 -0.144262465675995 0.88538517601307 25.938156795656 16.3032467286192 1.59098106208032 0.112613703529939 GPM6A other 1 1 1 -0.144262465675995 1.59098106208032 0.0268419585607434 139.96984736592 72.8560038408039 1.92118480272079 0.0556078130104031 -114.880124053928 124.575922342243 -0.92216956450318 0.357143666436204 VEGFC other 1 1 1 1.92118480272079 -0.92216956450318 0.901589545119942 2.16912421805184 5.4619912341506 0.397130666283312 0.691536679147097 3.53188937491181 8.29687829189986 0.425688945968986 0.670621570436266 CCDC102B other 1 1 1 0.397130666283312 0.425688945968986 0.000971070658633986 -7.46366220494704 5.63731088005571 -1.32397562663304 0.186462031473795 -30.4044842959049 8.54647490086101 -3.55754678374376 0.000431329331941305 CD226 other 1 1 1 -1.32397562663304 -3.55754678374376 0.627763332383842 3.25544151725394 3.48677761930878 0.933653324842468 0.351200139522734 6.83628144901765 9.74782690832901 0.701313381260023 0.483626886400793 DLG2 other 1 1 1 0.933653324842468 0.701313381260023 0.155126126683613 -4.19318903615697 2.16999219417263 -1.93235212892356 0.0542096148266775 0.854870029702329 7.42687286172451 0.115104976969248 0.90843502094732 RGS18 other 1 1 1 -1.93235212892356 0.115104976969248 3.62295900621705e-10 1264.3814040832 238.930844979648 5.2918299610538 2.27319898596593e-07 -380.468330398415 597.483008177275 -0.636785189187386 0.524727256667378 PRSS23 other 4.45551498584573e-06 1 0.00279057907517178 5.2918299610538 -0.636785189187386 3.16469737864642e-09 160.172375131339 24.8974620723974 6.43328121820554 4.61994639467424e-10 16.4090938212755 161.281394502618 0.101742013527848 0.91902598059901 MTMR12 other 3.75364756081252e-05 1 6.1976580884555e-06 6.43328121820554 0.101742013527848 0.132023303354798 8.25286956011237 5.54432901940359 1.48852449615267 0.137609887288482 -17.9447996284302 16.2633989965264 -1.10338556117715 0.27069931109758 PPP1R1C other 1 1 1 1.48852449615267 -1.10338556117715 0.655062080761735 -9.50567414274405 10.3748217971391 -0.916225293177107 0.360245216817588 -12.3679987021786 18.966199293983 -0.652107389069896 0.514804440632308 C11orf53 other 1 1 1 -0.916225293177107 -0.652107389069896 1.60593051251586e-27 1914.46922494361 157.462526205241 12.1582529575846 3.43178053122278e-28 -466.607215352359 928.488005852985 -0.50254522665987 0.615631879947864 CCT5 essential 2.41403474641385e-23 1 5.19914750480251e-24 12.1582529575846 -0.50254522665987 8.54413436668969e-14 41.2185864923802 5.50496559400685 7.48752844836197 6.96329277474034e-13 -79.1078790082314 32.4603869241023 -2.43705902807624 0.0153552488806571 FAM173B other 1.15029680978743e-09 1 9.78969331200744e-09 7.48752844836197 -2.43705902807624 0.000802661869465009 138.813343894562 75.7419682233666 1.83271371408247 0.0677741708038529 -347.522810756667 153.419092495895 -2.26518619751296 0.0241694894962246 DOCK1 other 1 1 1 1.83271371408247 -2.26518619751296 2.557238871875e-06 83.8426179075341 17.7544640780573 4.722340113389 3.50656598441438e-06 46.2936734412288 32.6225935729903 1.41906784136125 0.156861730209277 DIXDC1 other 0.0256414341682906 1 0.0405429159117991 4.722340113389 1.41906784136125 7.50422357869593e-23 233.210252640914 38.5952597084731 6.0424584366695 4.2423164055794e-09 -219.804491326543 70.774978233603 -3.1056808043239 0.0020693525102601 DLAT other 1.10867399151654e-18 1 5.54810139521674e-05 6.0424584366695 -3.1056808043239 5.48320455397521e-05 0.843929389324562 3.75852852973663 0.224537177953442 0.822483545483652 -22.7008077138802 6.89229135629024 -3.29365178289545 0.00110041256439467 PIH1D2 other 0.486963396438538 1 1 0.224537177953442 -3.29365178289545 6.37514694792664e-11 90.9579063424462 42.658930308429 2.13221254459055 0.0337553228499715 -298.803715301614 78.2268311407431 -3.81970879996425 0.000160653949144395 TIMM8B other 8.03077261030319e-07 1 1 2.13221254459055 -3.81970879996425 4.30193877808938e-17 -17.795849253742 68.8396581476696 -0.258511586672434 0.796179346195074 -911.475288693427 126.236365393349 -7.22038602627142 3.84524644939269e-12 IL18 other 6.07003561588412e-13 5.89130208511455e-08 1 -0.258511586672434 -7.22038602627142 1.05594776082513e-18 40.2417431554901 19.969123177905 2.01519830375005 0.0447249986627403 -219.045327347869 36.6188560184787 -5.98176325435545 5.93783579527673e-09 PTS other 1.5150738472319e-14 9.03382337893401e-05 1 2.01519830375005 -5.98176325435545 4.80275894494299e-07 56.572838721281 25.4482836967736 2.22305124366612 0.0269106027937939 -158.993862661363 50.6398653845768 -3.13969757727254 0.00184891386124513 PIP4K2A other 0.00508468089501114 1 1 2.22305124366612 -3.13969757727254 0.00310289197301539 284.742241739362 83.0338686426052 3.42923010085139 0.000684813504668571 225.813808033661 149.952230093123 1.50590496649117 0.133081110147583 FREM2 other 1 1 1 3.42923010085139 1.50590496649117 5.18186191690658e-09 128.921286609856 38.3911848216637 3.35809606316467 0.000880149547204248 -227.818553600068 69.5103632912726 -3.27747608864349 0.00116322932808806 FOXO1 og 6.0959423590489e-05 1 1 3.35809606316467 -3.27747608864349 7.36031126764203e-05 550.601924940727 126.409181738485 4.35571148684285 1.78827319645186e-05 659.027532215654 433.180350509994 1.52136986693825 0.129154541981284 CRIM1 other 0.643880029693325 1 0.197175002640782 4.35571148684285 1.52136986693825 0.0322661151309627 149.125892787974 73.6640326611504 2.02440577037023 0.0437639713586666 -114.851895190709 133.997873619735 -0.857117296626966 0.392025529333866 SEC24D other 1 1 1 2.02440577037023 -0.857117296626966 0.344379165204074 48.4839833084336 34.8413663970739 1.39156377381644 0.165024126303189 59.3229513724644 89.8163951591245 0.66049134200236 0.509415232013346 ABCB9 other 1 1 1 1.39156377381644 0.66049134200236 0.926594072620813 -0.804286229457568 26.1655935252505 -0.0307383139878486 0.975497457659501 25.6215196631712 67.4514099376511 0.379851506245081 0.704308410089789 RILPL2 other 1 1 1 -0.0307383139878486 0.379851506245081 2.05098751409052e-08 161.848327760571 26.8987849781794 6.01693823315305 4.85933475298748e-09 -0.733139998192588 69.009419346538 -0.0106237670905626 0.991530239781221 DHX37 essential 0.000234694501237378 1 6.34288965307456e-05 6.01693823315305 -0.0106237670905626 0.237484277853953 2458.57718754876 2009.49782241854 1.22347840346984 0.222049206147704 -4847.57052574503 5155.41047730334 -0.940287984261667 0.347779096908645 UBC other 1 1 1 1.22347840346984 -0.940287984261667 0.584559402260257 18.0245060025429 37.8938303234257 0.475658064880294 0.634647690277793 -37.3634531461861 61.9875227329579 -0.602757643778534 0.547103617895471 ITPR1 other 1 1 1 0.475658064880294 -0.602757643778534 0.230233013005409 6.31358621308278 18.1725047441858 0.34742520648414 0.728506899709044 -94.5556757787095 62.4726781940199 -1.51355246024591 0.131154946990262 PRSS53 other 1 1 1 0.34742520648414 -1.51355246024591 0.745168175912307 182.335511822866 252.594908071603 0.72184951476211 0.470920795876474 222.301955704955 445.46962508628 0.499028313461101 0.618106655477684 SLC7A11 other 1 1 1 0.72184951476211 0.499028313461101 5.49940989366858e-05 98.4724751811671 26.7991393668751 3.67446408756258 0.000279893037206104 -51.5556731959493 47.3314258988745 -1.08924825772416 0.27687439601362 NOCT other 0.488237610359896 1 1 3.67446408756258 -1.08924825772416 0.298300767971172 -14.5830000124035 10.6696855524987 -1.36676942733221 0.172660060281528 -28.3138925934534 21.454540148487 -1.31971565913288 0.187876279564502 ENKUR other 1 1 1 -1.36676942733221 -1.31971565913288 0.369421685064993 6.79210083537522 12.6023601706247 0.538954667492138 0.590295236780283 -22.3067075990593 25.478745306977 -0.875502593644238 0.38196130162951 GPR158 other 1 1 1 0.538954667492138 -0.875502593644238 0.0628252797468037 3.60072114411451 1.61449065647898 2.23025207960464 0.0264394263657632 8.78831178573215 7.89849270475326 1.1126568212747 0.266709655933703 CACNA2D4 other 1 1 1 2.23025207960464 1.1126568212747 0.0961477550438988 19.281583468874 8.87720315941048 2.17203359240846 0.0306035596717554 12.9109092619361 43.4295015036708 0.297284307093529 0.766446662948831 DCP1B other 1 1 1 2.17203359240846 0.297284307093529 0.0173354773893434 24.9973878833325 9.06479948757483 2.75763274384575 0.00616311033398768 -15.6758576449725 44.3743225668323 -0.353264156796153 0.724127460309024 CACNA1C other 1 1 1 2.75763274384575 -0.353264156796153 0.531314270615077 26.7288796715995 27.9920151118557 0.954875151531296 0.340361604863539 -3.10654075455438 43.0037375997266 -0.0722388547588509 0.942456953468364 THRB other 1 1 1 0.954875151531296 -0.0722388547588509 1.06469153694958e-16 84.414403545499 21.9725274353326 3.84181582177741 0.000147266352870123 -169.6800952117 32.5475537798531 -5.21329794427536 3.3349855908422e-07 NGLY1 other 1.49525279449199e-12 0.00502315529692653 1 3.84181582177741 -5.21329794427536 3.15074174921352e-19 40.8797159159258 8.30569018353071 4.92189270399056 1.37477939716857e-06 -60.9488237116258 12.3030861480488 -4.9539459431723 1.18014486331399e-06 OXSM other 4.54273945401605e-15 0.0176655884589472 0.0162801376212702 4.92189270399056 -4.9539459431723 8.09160735138641e-19 83.8340374447868 19.5565417155475 4.28675164884284 2.40457146095889e-05 -241.709961852496 40.9166600680604 -5.9073727291142 8.91034145734057e-09 UEVLD other 1.1626021442472e-14 0.000135463921175949 0.262771569253587 4.28675164884284 -5.9073727291142 0.000179811805543343 50.4049533195023 27.9782301677936 1.80157762007136 0.0725559973395468 -151.653354080221 58.5367162421905 -2.59073900648558 0.0100167938434128 TMEM86A other 1 1 1 1.80157762007136 -2.59073900648558 0.224407042391041 22.561452033443 13.4424034498051 1.67837932537058 0.0942493151547591 23.2977873362142 34.4933257434185 0.675428849903218 0.499891113893228 C12orf45 essential 1 1 1 1.67837932537058 0.675428849903218 0.00140864026277126 165.756172512337 45.7588304354959 3.6223865630918 0.000339327445896859 0.465505753367915 124.875629742053 0.00372775500175237 0.997028011517193 TMEM263 other 1 1 1 3.6223865630918 0.00372775500175237 0.000193959149016481 173.638157624321 50.2658138803151 3.45439861051013 0.000625832756109852 -252.762130314483 137.175166040345 -1.84262310453586 0.0663089502976898 BTBD11 other 1 1 1 3.45439861051013 -1.84262310453586 4.26881512762418e-09 173.584514322886 33.7161080558204 5.14841493672697 4.59682634385946e-07 -284.255313484965 94.5549330280869 -3.00624519929096 0.00285426672362528 UBE3B other 5.04147066572416e-05 1 0.00556491797187627 5.14841493672697 -3.00624519929096 0.0581099132835819 42.0301990726407 72.897189906682 0.576568165747472 0.564641670904756 -331.30366162831 166.703415580893 -1.98738376459686 0.0477428487074183 ANK3 other 1 1 1 0.576568165747472 -1.98738376459686 0.00056834637726056 39.3891395817266 21.7522346354987 1.81080887742196 0.0711200043049995 -131.173892195009 49.7436432720743 -2.63699808792753 0.00877774922047003 IPMK other 1 1 1 1.81080887742196 -2.63699808792753 0.219080865861302 -4.00259624096833 2.52854294689246 -1.58296549634937 0.114417116603479 -6.82527259562143 7.09115680274328 -0.962504819098206 0.336522831380048 RAD9B other 1 1 1 -1.58296549634937 -0.962504819098206 0.000108604337181539 437.133490156561 104.272410664166 4.19222579944423 3.57901202323564e-05 -141.360466105163 277.856730447597 -0.508753075289723 0.611275895088101 PLBD2 other 0.932042421691968 1 0.386425928148752 4.19222579944423 -0.508753075289723 0.0595649995541371 145.035483870968 165.324051574335 0.877279999430423 0.380994776415005 -659.64608294931 384.64996407229 -1.71492563255599 0.0873300071513532 DLG5 other 1 1 1 0.877279999430423 -1.71492563255599 0.870222873546845 -4.16753638034408 8.22234577633848 -0.506854916310749 0.61260678870846 -1.05999216655117 19.1996601098968 -0.0552089026828541 0.956006597505949 MAT1A other 1 1 1 -0.506854916310749 -0.0552089026828541 0.77373870438488 7.36438908867659 10.8080541769798 0.681379734787239 0.496138298194367 -2.41392640996396 29.2429068888096 -0.0825474163407366 0.934264516885139 SLC2A13 other 1 1 1 0.681379734787239 -0.0825474163407366 0.00349753130490259 39.2936925098553 12.9685724142269 3.02991657483818 0.00264881804085495 -30.9699987634838 34.6675585182796 -0.893342366384235 0.372355845909341 GXYLT1 other 1 1 1 3.02991657483818 -0.893342366384235 1.43056346825592e-05 337.335668249661 83.4897613755592 4.04044355489573 6.70940872075582e-05 -409.839038495207 230.573160292227 -1.77747938214395 0.0764541724036966 TWF1 other 0.134744773075026 1 0.707842620039739 4.04044355489573 -1.77747938214395 0.000397431727008354 99.3261251593495 27.1154481307493 3.66308256018504 0.000292972596353162 21.6702404672138 53.9205111398221 0.401892341321105 0.688040195885062 DIP2C other 1 1 1 3.66308256018504 0.401892341321105 1.11474372370127e-10 181.982324510189 34.7442577444248 5.23776693831918 2.95244921680346e-07 -144.715972607255 62.7420900142928 -2.30652138897969 0.0217200134898171 EIF4E essential 1.39108869280682e-06 1 0.00360582622848207 5.23776693831918 -2.30652138897969 0.0130416687260871 37.015835006952 30.8992634269443 1.19795201896865 0.231827797395566 -71.2626521023983 43.490719634517 -1.63857146309071 0.102291515776171 MAGI1 other 1 1 1 1.19795201896865 -1.63857146309071 0.000363542766587028 46.7832572366021 12.6108338963737 3.70976714315892 0.000244895628661533 -19.6894034332986 29.2016432725918 -0.674256693347757 0.500639518083713 TEX30 other 1 1 1 3.70976714315892 -0.674256693347757 1.68258811507411e-10 88.3305330860387 26.2757105336442 3.36168009511817 0.000868584570488847 -166.529685054894 38.8172358426789 -4.29009643370322 2.36857069732072e-05 CSNK1G3 other 2.09078399179108e-06 0.345148122013576 1 3.36168009511817 -4.29009643370322 5.22203828548537e-08 56.6664756551243 18.5213012696729 3.05952993421208 0.00240426708764559 -96.2501870838154 27.2321565357127 -3.53443132414399 0.000468897143667829 SRFBP1 essential 0.000584607186060088 1 1 3.05952993421208 -3.53443132414399 0.000385562434367815 109.809714596771 27.3703451523318 4.01199597541122 7.53728728214399e-05 91.5268019151747 87.1681794876728 1.05000244875044 0.29452701368072 AKAP6 other 1 1 0.791565910370762 4.01199597541122 1.05000244875044 4.3659039582811e-24 98.8289191167725 9.24074978240983 10.6949026262888 6.24910536775287e-23 -35.8978191506464 29.7721532439875 -1.20575152413257 0.228832803914193 MBIP other 6.48074783567246e-20 1 9.37115840948221e-19 10.6949026262888 -1.20575152413257 0.000280313690396778 27.9590725374929 6.85150429027357 4.08072028462184 5.71630327196842e-05 12.2315327818848 22.1454082753989 0.552328167978401 0.581121528233704 MIPOL1 other 1 1 0.606156798959531 4.08072028462184 0.552328167978401 1.01741224563278e-12 720.07081396499 122.730855495082 5.86707239235241 1.14128829871161e-08 -537.553146230684 292.72488545266 -1.83637665584677 0.0672625073609355 EXT2 ts 1.34023715117206e-08 1 0.000147157713235874 5.86707239235241 -1.83637665584677 0.00191600582272915 35.0633004675751 17.9180932358778 1.95686561097735 0.0512520047889492 -135.873829279949 55.5521892939205 -2.44587712936129 0.0150004086332649 TMEM18 other 1 1 1 1.95686561097735 -2.44587712936129 4.75457860565262e-06 36.6615995007134 13.9234656734553 2.63308003628779 0.00887741079391135 -115.178244441438 45.0895017577471 -2.55443595407769 0.0111046498482377 KCTD14 other 0.0467089802219314 1 1 2.63308003628779 -2.55443595407769 1.14135402678881e-23 671.029110199716 69.2537698818074 9.6894235699361 1.31001143874385e-19 -85.1638315337694 224.270167503595 -0.379737673011744 0.704395229852777 NDUFC2 other 1.69205734471441e-19 1 1.94025794192351e-15 9.6894235699361 -0.379737673011744 0.00176928867668751 23.2907237789037 6.99711491548173 3.32861816051798 0.000976251920727173 12.5433294630325 17.5112334336927 0.716301881905035 0.47433566345655 ME3 other 1 1 1 3.32861816051798 0.716301881905035 0.209453635453867 68.1385810044208 38.7191751530503 1.7598148910735 0.0794067450206172 -9.97395883144831 251.027830271697 -0.0397324823333458 0.968331495397701 ADAMTS12 other 1 1 1 1.7598148910735 -0.0397324823333458 4.44905873798118e-31 108.709023217269 8.2696269087455 13.1455777167292 9.93183353539662e-32 33.3522634894453 26.0847187316648 1.27861311569207 0.201980567100438 NUBPL other 6.73409530580831e-27 1 1.5113271090813e-27 13.1455777167292 1.27861311569207 0.0727993405365135 156.441302907692 69.2687964255226 2.25846717397345 0.0245938440477139 -93.3533369076491 238.340163208657 -0.391681098354884 0.695556196986178 NEK7 other 1 1 1 2.25846717397345 -0.391681098354884 6.58466355118002e-07 117.829213461181 35.2705378544239 3.34072630101393 0.000934438540444736 -135.910732104791 49.9423545176096 -2.72135211520452 0.00685737427210257 FER other 0.00690204433434689 1 1 3.34072630101393 -2.72135211520452 8.73071532248061e-31 150.298327953397 11.8894468912085 12.6413221177289 5.48307149233776e-30 -28.435110159787 38.7657095666556 -0.733511922718566 0.46378329540328 VIPAS39 other 1.32069530683164e-26 1 8.3293339040103e-26 12.6413221177289 -0.733511922718566 0.000194293891968289 278.19611091525 67.6963578315073 4.10946939874765 5.05106676830135e-05 84.6412705530156 122.034742657839 0.693583390349194 0.488449810416107 ANKRD50 other 1 1 0.538645760171656 4.10946939874765 0.693583390349194 4.50388000271899e-16 196.496440483307 38.6170755037913 5.08833043206537 6.18990844828076e-07 -295.58322975992 79.0459880785707 -3.73938307237192 0.000218737952390537 UPF2 essential 6.28471415579408e-12 1 0.00745079279919555 5.08833043206537 -3.73938307237192 1.79843593184727e-23 471.556985418061 57.3404119799704 8.223815789513 5.09074797241446e-15 -275.199987526242 117.371123075959 -2.34469927793178 0.0196572184659443 CDC123 essential 2.66456267662491e-19 1 7.33627690304647e-11 8.223815789513 -2.34469927793178 0.000573705655781857 9.74046536082591 13.7517751391173 0.708306037750639 0.47927409120509 -80.639759532159 24.1724662859211 -3.33601704428177 0.000950515079221315 SCLT1 other 1 1 1 0.708306037750639 -3.33601704428177 0.031229993168182 160.448628897769 93.2607361842668 1.72043064919357 0.0863269829535406 -166.314987728518 190.897082299682 -0.871228547471595 0.38428662321482 CCDC3 other 1 1 1 1.72043064919357 -0.871228547471595 1.26750066134079e-07 5.48081723500385 10.6496879730704 0.514645804540287 0.60715805069631 -96.5371041185417 18.59789980952 -5.19075299400882 3.74255264461512e-07 C4orf33 other 0.00139044822549084 0.00563478726173252 1 0.514645804540287 -5.19075299400882 0.0150956067111583 -80.4168755482096 54.0271666271824 -1.48845257984989 0.137622563443786 -322.001505173093 110.457158365816 -2.91517100328325 0.00380730614643097 FRMD4A other 1 1 1 -1.48845257984989 -2.91517100328325 0.889196061846742 -5.69626694882668 11.832246657712 -0.481418881266644 0.63054888947535 -7.04842809825745 45.4175334922016 -0.155191785116814 0.876768274346467 PTPRO other 1 1 1 -0.481418881266644 -0.155191785116814 0.000118535049334114 192.252365640122 47.3424662483418 4.06088615307099 6.16172055018361e-05 -105.330557164285 180.661504502536 -0.583027122763755 0.560288259016617 EPS8 other 1 1 0.652042969812337 4.06088615307099 -0.583027122763755 3.9976087492553e-10 41.307990563552 16.7108500276226 2.47192635295458 0.0139879359797585 -102.005172420907 30.5239257105036 -3.34181040107192 0.000936649642631604 ACAD8 other 4.90986306583536e-06 1 1 2.47192635295458 -3.34181040107192 0.000197029882389364 31.8246449394926 29.0879356386898 1.0940839987683 0.27478713045901 -129.103384459217 53.1318266299824 -2.42986911325882 0.0156849872558273 THYN1 other 1 1 1 1.0940839987683 -2.42986911325882 5.62820616499633e-27 269.817530465968 39.3480507838941 6.85720194750815 3.94714899753295e-11 -246.572021886335 71.8728836052861 -3.4306682787415 0.000685676389109934 VPS26B other 8.44512335057699e-23 1 5.40246283292335e-07 6.85720194750815 -3.4306682787415 5.44923641925604e-11 243.0811408977 57.8741562901115 4.20016733685383 3.51128924380962e-05 -190.854522309288 105.712542703536 -1.80541038393644 0.0720029613185735 NCAPD3 essential 6.8785711320269e-07 1 0.379394802793629 4.20016733685383 -1.80541038393644 1.30908792969411e-10 38.1371228312637 15.2770512942972 2.49636674621234 0.0130499810896733 -140.915123148136 29.0337988466556 -4.85348554945879 1.89926036117607e-06 VTI1A other 1.62994538126213e-06 0.0283521586716364 1 2.49636674621234 -4.85348554945879 3.38417947291465e-06 74.2009823986898 38.9314955542752 1.90593711703792 0.0575598196462446 -207.950359792044 73.1013113449917 -2.84468713304814 0.00473369902091455 QDPR other 0.0336150547044613 1 1 1.90593711703792 -2.84468713304814 0.263202139397744 15.6162534145829 21.0202305546576 0.74291542016996 0.458077920532108 -40.7568549710059 40.5464350689563 -1.00518960302408 0.315565036853167 FAM160B1 other 1 1 1 0.74291542016996 -1.00518960302408 0.600644531105424 -5.16066843072593 7.85017232316108 -0.657395560031203 0.511400650127145 -17.0420995346533 20.0970474317784 -0.847990213114864 0.397079234605742 ANO4 other 1 1 1 -0.657395560031203 -0.847990213114864 0.00938489697838105 -28.7347322671557 9.76748125073522 -2.94187739188062 0.00350112742409301 -37.1744004165111 19.2844296861175 -1.9276899043207 0.054781285691054 TEX9 other 1 1 1 -2.94187739188062 -1.9276899043207 4.13556956469794e-23 191.139761904762 17.504292473657 10.9195937049394 8.33120684626813e-24 71.0554160487723 72.4441631863883 0.980830103123106 0.327417486286166 QTRT2 other 6.11774805705767e-19 1 1.25159720451486e-19 10.9195937049394 0.980830103123106 6.25411770946942e-06 11.5738525187991 9.76960085314222 1.18468018220791 0.237036977126472 -68.5310493892499 16.909016514567 -4.05292935459674 6.37792607786698e-05 MMAA other 0.0607712617829144 0.916571756650264 1 1.18468018220791 -4.05292935459674 0.0134173396358406 45.0980745995088 28.8793845923573 1.56160095639447 0.119386090731882 -87.207926364088 49.9838220970554 -1.74472304648398 0.0820083565386404 ZNF827 other 1 1 1 1.56160095639447 -1.74472304648398 0.0190254961397941 111.679430203171 42.6639087549756 2.61765584687894 0.00927969000277318 -1.24877922085353 73.7272007000279 -0.016937835819027 0.986496897560099 EDNRA other 1 1 1 2.61765584687894 -0.016937835819027 0.299319800845252 -8.41588522050071 18.98595846396 -0.443268915629207 0.657875517396973 -50.5440615525054 32.6251007896519 -1.54923847985588 0.12232847654633 NR3C2 other 1 1 1 -0.443268915629207 -1.54923847985588 4.57449074503675e-05 7754.22435503686 1810.12657132729 4.28380229198614 2.43491899939563e-05 2750.47176153427 3709.69237901643 0.741428528438661 0.458979122867687 AKR1C2 other 0.410148840199995 1 0.265990551493978 4.28380229198614 0.741428528438661 0.251746231045972 31.6798179325858 19.0570626767121 1.66236625601798 0.0974246908615544 30.8692734877507 38.5615997034798 0.800518487954874 0.424008104379744 DPYSL4 other 1 1 1 1.66236625601798 0.800518487954874 0.0346835392234072 -188.945857468677 130.471769267735 -1.448174256616 0.148575706956161 -679.8540958163 263.62981264178 -2.57882099525703 0.0103731802010453 ADAM8 other 1 1 1 -1.448174256616 -2.57882099525703 3.14423642104326e-20 50.4003565301738 7.9498051244441 6.33982289392259 7.87853900160208e-10 -62.2284787605829 16.107208673239 -3.86339309454475 0.000135529747042976 KIN essential 4.57014763798637e-16 1 1.05162738593384e-05 6.33982289392259 -3.86339309454475 2.61314628081093e-10 102.011533161107 14.9994417627074 6.80102198301373 5.10856629471302e-11 -0.246372790699785 54.6020589683104 -0.0045121520205451 0.996402647346551 PIGF other 3.2301101177104e-06 1 6.97319299228327e-07 6.80102198301373 -0.0045121520205451 0.00333981523583078 3.75994366741478 1.42072390282881 2.64649849272497 0.00854552692224695 -5.66625544374919 3.60977969837749 -1.56969563718695 0.117499510006216 ANKAR other 1 1 1 2.64649849272497 -1.56969563718695 0.000762640549351482 -159.931842446905 67.3624160832418 -2.37419991363244 0.018193813981179 -583.745056729038 170.48352910227 -3.4240554486578 0.000699664947668701 INPP1 other 1 1 1 -2.37419991363244 -3.4240554486578 0.000230340195375182 248.200308320137 73.9981518053408 3.35414199226288 0.000894300212733437 -351.291362530415 201.739432016661 -1.74131234047195 0.0826145037790596 MFSD6 other 1 1 1 3.35414199226288 -1.74131234047195 0.0380634048650384 95.1049831478693 37.0072913402607 2.56989851738766 0.0106265696885676 70.4774089797482 111.39312413038 0.632690837338023 0.527388803629212 RNF144A other 1 1 1 2.56989851738766 0.632690837338023 8.90243106108407e-06 240.276488696456 53.7159301794557 4.47309555831452 1.07460162741441e-05 -147.973479416448 163.227326989541 -0.906548444709441 0.365332032907015 ASAP2 other 0.085356509013674 1 0.120280160156495 4.47309555831452 -0.906548444709441 3.51236675235758e-11 484.855590366161 70.9002570800406 6.8385589888454 4.08562649424597e-11 -107.654200117486 213.412029137098 -0.504442980804649 0.614298371225523 ADAM17 other 4.45578846204082e-07 1 5.58872848147906e-07 6.8385589888454 -0.504442980804649 0.0405205952028895 -8.08023238529378 19.2416779173737 -0.419933875828884 0.674819134999806 58.8425618537972 35.1963347438252 1.67183777180436 0.0955461749804239 FLI1 other 1 1 1 -0.419933875828884 1.67183777180436 4.1293309203874e-06 12.5057976923973 82.4178374252934 0.151736542514029 0.87949125526206 -576.450282405709 150.583396121404 -3.82811317351989 0.000155590166996175 TMEM45B other 0.040727590867781 1 1 0.151736542514029 -3.82811317351989 1.23935572656807e-07 84.0266875727276 21.6579474027805 3.87971611575435 0.000127210531452039 -93.8568754280738 40.3821013926744 -2.32421969613251 0.0207453925173381 WWC2 other 0.00136019290990845 1 1 3.87971611575435 -2.32421969613251 0.000366571991151895 -49.2931697691121 52.711718270192 -0.93514632773766 0.350420244239278 -388.580561520234 98.3861916078836 -3.94954368260248 9.64096939441273e-05 CENPU other 1 1 1 -0.93514632773766 -3.94954368260248 0.00151084367724466 287.971614211536 138.607242143335 2.07760871480108 0.0385450240234988 -477.885928229061 258.709811238806 -1.84718904142349 0.0656455941803895 ACSL1 other 1 1 1 2.07760871480108 -1.84718904142349 0.69225471590013 156.503702855398 182.605735017016 0.857057982548107 0.392056235776171 111.224296917517 341.331937393224 0.325853765009348 0.744748644683639 SLC25A4 other 1 1 1 0.857057982548107 0.325853765009348 1.99751793905686e-19 45.397796268442 4.63649079819472 9.79141299840782 6.3632959378897e-20 -13.2817486478702 27.4050002824307 -0.48464690789969 0.628265810586034 AMN1 other 2.88421615220421e-15 1 9.44504016060969e-16 9.79141299840782 -0.48464690789969 1.24069060837825e-22 148.803480358307 13.790788382439 10.7900633547384 2.88028204885333e-23 -15.7142841455009 81.4411439366716 -0.192952645136226 0.847121999876974 BICD1 other 1.8306389926621e-18 1 4.3224392707142e-19 10.7900633547384 -0.192952645136226 6.27682583926478e-12 161.56019964021 23.305897226818 6.93215961899566 2.32782765779676e-11 -85.2568483391515 70.7399355525484 -1.20521523907552 0.229019133399549 SAV1 other 8.11844654050506e-08 1 3.19866798457853e-07 6.93215961899566 -1.20521523907552 2.36048592051646e-06 8.00742665733594 3.62485834045088 2.20903161041596 0.0278873198118564 -22.7010746063941 6.72308929287292 -3.37658383184934 0.000825291641602146 CCDC122 other 0.0237276044730315 1 1 2.20903161041596 -3.37658383184934 2.81718844496473e-09 166.259279509336 27.1368118697033 6.1267064203277 2.65749539326387e-09 -70.4451510522353 86.9887216639543 -0.809819361691181 0.418651466929293 NBAS essential 3.34963706106306e-05 1 3.49752968707457e-05 6.1267064203277 -0.809819361691181 0.064550340387928 3.12089875962678 5.88081908098692 0.530691170166559 0.596000903602817 20.4928562488414 9.0346193233911 2.26825896203334 0.0239794582994964 ZNF385D other 1 1 1 0.530691170166559 2.26825896203334 0.589790164465127 15.1160394618948 21.9255816064763 0.689424788505033 0.491057165834846 -14.7887875147898 37.5001550337101 -0.394366036660266 0.693574328310212 TDO2 other 1 1 1 0.689424788505033 -0.394366036660266 1.66356074174323e-14 80.4078077637417 22.3080769646918 3.60442578224056 0.000363682618526473 -195.403056173672 43.1924482989215 -4.52400972552766 8.61669847709804e-06 GUF1 other 2.26726693492185e-10 0.127001518853948 1 3.60442578224056 -4.52400972552766 0.0379492644652778 73.4333364579723 55.7705116178721 1.31670544751539 0.18888253673849 -122.146364326625 90.1850014361526 -1.3543977643899 0.176568066417699 SACS other 1 1 1 1.31670544751539 -1.3543977643899 0.00179539751459944 3.71315965107206 1.15924120222823 3.20309495895661 0.00149683493816225 -2.95979330019326 3.66596737031375 -0.807370333997257 0.420054737136992 CCDC175 other 1 1 1 3.20309495895661 -0.807370333997257 0.663625527217206 119.144392180724 131.543844119171 0.905739017880504 0.365755458035961 96.0210575993014 246.773809944023 0.389105544146206 0.697456867247478 PABPC3 other 1 1 1 0.905739017880504 0.389105544146206 1.01567921854459e-06 -10.5459923196342 16.8113957910437 -0.627312119155065 0.530901999631341 -161.664325516791 31.5558186607615 -5.12312252946919 5.20492016915721e-07 CENPJ other 0.0105122799119365 0.00782507698231094 1 -0.627312119155065 -5.12312252946919 6.46934831938765e-08 46.8657892601744 8.18494628282041 5.72585178213596 2.42532648754431e-08 -54.3398974545557 57.6791821317779 -0.942105894123238 0.346869657214069 FBXO4 other 0.000720814789746172 1 0.000309374646751152 5.72585178213596 -0.942105894123238 4.44225006771926e-13 76.4376013966961 9.68046500359891 7.89606711746583 5.02680571806135e-14 28.0188282680617 68.1820971141819 0.410941133434774 0.68139961793986 TMEM267 other 5.89442161485669e-09 1 7.17978660710703e-10 7.89606711746583 0.410941133434774 0.745810312278093 53.9591764487156 86.8671265884922 0.621169118489801 0.534944827192559 -239.162123924908 611.828342841443 -0.390897425271598 0.69614156455398 CCL28 other 1 1 1 0.621169118489801 -0.390897425271598 1.54012763787598e-06 56.5911195435127 27.4978875798505 2.05801697963813 0.0404464223248208 -151.883161387517 41.3750636673669 -3.67088646941006 0.000285730730825379 PARP8 other 0.015721622927438 1 1 2.05801697963813 -3.67088646941006 0.933778865189413 -7.18911536036983 20.8687471617959 -0.344491947917737 0.730702635690628 -0.950728628673974 40.2542350601733 -0.0236181019774142 0.981171953496346 GFRA1 other 1 1 1 -0.344491947917737 -0.0236181019774142 2.44376240154108e-15 316.78618750796 69.4116147824066 4.56387866066839 7.16821164171959e-06 -634.63788212871 135.120358488927 -4.69683391330492 3.9273893466911e-06 CACUL1 other 3.37776839141008e-11 0.0583610056918298 0.0812875200171002 4.56387866066839 -4.69683391330492 2.25613102955964e-14 4833.26551091158 598.374575080526 8.0773243252542 1.59750600335132e-14 -220.885311649267 1978.33126044478 -0.111652338546986 0.911173241977421 DST other 3.06856381330407e-10 1 2.29178211240781e-10 8.0773243252542 -0.111652338546986 8.07659031212311e-07 23.0494143348246 5.16787696741288 4.46013217423083 1.16322235577446e-05 -26.9998244867462 14.4868165559561 -1.86375138957948 0.0633432887380849 BEND6 other 0.00841419178716985 1 0.129862143798661 4.46013217423083 -1.86375138957948 2.82708550315463e-06 63.7630045157859 47.7343889445123 1.33578759308945 0.182567951388094 -365.451978787329 92.9223123053922 -3.93287650425938 0.00010294928754269 TIAL1 other 0.028248238347521 1 1 1.33578759308945 -3.93287650425938 2.62518945457475e-07 447.254157428845 185.232362148967 2.41455732810423 0.0163149586768448 -1288.8098271631 360.583214434351 -3.57423689060197 0.000405374154459519 BAG3 other 0.00283126682675887 1 1 2.41455732810423 -3.57423689060197 0.00347508411126904 -2.82006308222942 4.43806151440138 -0.635426767537674 0.525605660187083 34.1653270262343 10.8569806975878 3.14685343723833 0.00180609486502856 GLT1D1 other 1 1 1 -0.635426767537674 3.14685343723833 7.67997427643122e-09 76.6524166527493 12.2943818587392 6.23475157461965 1.46278137068378e-09 -71.2804823737353 72.4647993679521 -0.983656658066447 0.326044090114212 SCHIP1 other 8.96252998059523e-05 1 1.9373076473336e-05 6.23475157461965 -0.983656658066447 0.454951798644045 15.9470557090931 12.7111218056146 1.25457500549237 0.210548636608092 11.4840121996584 22.1727587959128 0.517933393194867 0.604862629130541 KCNE4 other 1 1 1 1.25457500549237 0.517933393194867 0.0084112818318543 18.1249077445907 13.4393148238628 1.3486481998627 0.178406645524465 -43.6619303705656 23.4562494668045 -1.86141993554239 0.0636045184572463 AP1S3 other 1 1 1 1.3486481998627 -1.86141993554239 0.0304693240806546 83.4733320143413 31.4971285738322 2.65018862969276 0.00844827810207768 -26.7943084259554 101.398595328227 -0.264247333399661 0.791761052204272 RABGAP1L other 1 1 1 2.65018862969276 -0.264247333399661 0.541235684096748 -1.53289284889379 7.79653407791179 -0.196612088599291 0.844255918085368 -23.4641884750792 21.1846836909104 -1.10760154918654 0.268865774374752 CCDC74B other 1 1 1 -0.196612088599291 -1.10760154918654 0.429292572351905 -12.9151775466377 14.711165077036 -0.877916703334269 0.380649654188781 19.1685736585167 31.1222473746305 0.615912258127671 0.538391639630253 TMEM56 other 1 1 1 -0.877916703334269 0.615912258127671 0.324311714307739 150.921832676572 145.395481737649 1.03800909679501 0.300049518072721 -374.782994337628 395.067508192643 -0.948655575479208 0.343511681604655 MZT2B other 1 1 1 1.03800909679501 -0.948655575479208 4.91008530394837e-07 531.749677086815 111.019647936091 4.78968981592266 2.5590012918668e-06 -622.69776202646 301.738756100594 -2.06369831331466 0.0398523111336111 FAM168B other 0.00519487025157738 1 0.0298328370605831 4.78968981592266 -2.06369831331466 0.261092997605923 148.443992945306 91.491267313683 1.6224935701935 0.105688644525019 -68.6863174170904 298.115697842834 -0.230401545152117 0.817927908768025 PTPN14 other 1 1 1 1.6224935701935 -0.230401545152117 0.00169595447038418 272.190864493807 80.3951514405194 3.38566268757126 0.000800280162446811 -166.007763489728 213.562938213583 -0.777324777783798 0.437552412088375 MGAT5 other 1 1 1 3.38566268757126 -0.777324777783798 0.10315976857731 -22.9331974942519 11.5952886757048 -1.97780306602483 0.0488249604565061 -33.1442504603129 30.8019062673241 -1.07604542954777 0.282733009077331 TMEM163 other 1 1 1 -1.97780306602483 -1.07604542954777 0.000178156814360873 38.1818336348515 10.8966683206421 3.50399154230673 0.000523859655554137 -64.0362428819469 37.332557483528 -1.71529215243829 0.0872627294471454 GPATCH11 other 1 1 1 3.50399154230673 -1.71529215243829 0.360531049522162 247.409321910616 173.02503375298 1.42990477472659 0.153723009602574 117.843918004376 478.734678786158 0.246157053638087 0.805718971175659 HSPB8 other 1 1 1 1.42990477472659 0.246157053638087 0.0078458588429816 29.1349723075086 9.59463870492067 3.03658878708654 0.00258997931944078 -8.70203365524314 32.8621408799006 -0.264804222191304 0.791331301655479 GEMIN6 essential 1 1 1 3.03658878708654 -0.264804222191304 0.0893645395814038 -7.20834658608992 3.8102191998041 -1.8918456414425 0.0594170637649131 11.029675226795 13.2533345664127 0.832218878315121 0.405907980321415 TMEM178A other 1 1 1 -1.8918456414425 0.832218878315121 0.74575085764246 -6.02055773486224 8.48823603083976 -0.70928255446575 0.478711245592987 -8.18205085247683 17.3801585096303 -0.470769633541787 0.638154336188256 POU4F1 other 1 1 1 -0.70928255446575 -0.470769633541787 6.70319015106082e-12 79.7643414870335 12.5794770763682 6.34083126053615 8.59124225058192e-10 -55.2499780687123 25.7572132491597 -2.14502933738434 0.0327697167267326 RNF219 other 8.66052167517058e-08 1 1.14538441684758e-05 6.34083126053615 -2.14502933738434 0.00819527149604702 -13.2142560850691 4.2502007150425 -3.10908989269628 0.00204632715439587 -11.9986549829619 7.91722986231934 -1.51551176252535 0.130636203661004 CYSLTR2 other 1 1 1 -3.10908989269628 -1.51551176252535 0.000348901848808242 19.9705267907187 5.93986181487618 3.36211976189466 0.000867554553747197 -7.99735962216902 11.0241983112811 -0.725436843238327 0.468715911075785 ARL11 other 1 1 1 3.36211976189466 -0.725436843238327 6.61073587472017e-11 167.829529556407 34.4048717728493 4.87807455480332 1.70340128022743e-06 -74.0815228911691 55.3737188214766 -1.33784626475975 0.181911590953641 SETBP1 other 8.32291646627269e-07 1 0.0200524398708374 4.87807455480332 -1.33784626475975 7.29545235885262e-07 37.8079271190649 13.9967478892917 2.70119369285704 0.00727828035932167 -95.5254645803842 30.9096636477916 -3.0904724706446 0.0021744422474356 ARL14EP other 0.0076230181697651 1 1 2.70119369285704 -3.0904724706446 8.25582986365819e-19 196.087652635085 38.649308684414 5.0735099620077 6.68518567867111e-07 -234.868499662422 62.2313710702166 -3.77411738843768 0.000191847853527421 EPG5 other 1.1859499599145e-14 1 0.00803091355578761 5.0735099620077 -3.77411738843768 2.83453987851911e-06 103.315592989402 45.4271022001801 2.27431616778305 0.023619214295288 -176.505161410551 73.1446680391491 -2.41309675937117 0.0163882512076524 PSTPIP2 other 0.0283198879262845 1 1 2.27431616778305 -2.41309675937117 2.93571872082185e-23 2573.70346588948 438.407318356224 5.87057596469738 1.10108888825922e-08 -2940.93731032312 705.903661338372 -4.16620209158171 4.00457073876882e-05 ATP5A1 essential 4.34662513804883e-19 0.579581523022011 0.000142116231913317 5.87057596469738 -4.16620209158171 2.79280674356677e-13 137.527558174703 29.3451869536082 4.68654564689332 4.14124342835389e-06 -116.390440927129 47.2502945226369 -2.46327440078428 0.0143017959236232 HAUS1 essential 3.72197354715144e-09 1 0.0476615706169249 4.68654564689332 -2.46327440078428 3.32355604455232e-23 233.020714947466 34.9855316900572 6.66048802721755 1.21630036830634e-10 -182.046561668808 56.4780924613507 -3.22331285875823 0.00139991316694435 C18orf25 other 4.91886294593744e-19 1 1.65039796975487e-06 6.66048802721755 -3.22331285875823 0.456948983219171 12.7633842478378 10.5881809005364 1.20543692705431 0.228925285363035 -4.6640069619187 31.866640069762 -0.146360173262958 0.883729223908969 SPC25 essential 1 1 1 1.20543692705431 -0.146360173262958 1.0086367248581e-08 191.207532894262 32.4210175379465 5.89764132697155 9.5556446488083e-09 -161.10063554742 121.421755424476 -1.32678559113424 0.185546750197681 PDK1 other 0.000117052291919783 1 0.000123506707085847 5.89764132697155 -1.32678559113424 0.318707854689233 -27.3725152668417 18.6989573326542 -1.4638524908039 0.144228288957324 -38.7379162591323 38.6614840000468 -1.00197696133665 0.317121354389769 PDE3B other 1 1 1 -1.4638524908039 -1.00197696133665 0.133465995932835 71.9451529147861 40.6727574805091 1.76887817230644 0.0778757752491909 187.411779251632 169.803322457591 1.10369912990624 0.270560783122049 TCF7L1 other 1 1 1 1.76887817230644 1.10369912990624 0.0171504457476669 411.293739457579 147.302135124731 2.79217771765024 0.00555332941251041 547.868015507848 614.966712332269 0.890890522236646 0.373663568308692 TGOLN2 other 1 1 1 2.79217771765024 0.890890522236646 0.000687464981010399 8.23696757161431 2.42212301726689 3.40072222298142 0.000757823649859506 19.474591100555 7.11606628064626 2.73670737912047 0.00655465589854139 KCNK13 other 1 1 1 3.40072222298142 2.73670737912047 0.00134476811803453 390.024038282421 106.330544425083 3.66803386920696 0.000286171360049716 -117.165977434016 365.057734639646 -0.320951910660576 0.748456340269983 UHMK1 other 1 1 1 3.66803386920696 -0.320951910660576 2.21947035439191e-05 636.547741945119 202.959581463586 3.13632762422366 0.00187015481871053 -547.794781561249 280.369633005861 -1.95383064737898 0.0515949068684574 ATG10 other 0.205323202484796 1 1 3.13632762422366 -1.95383064737898 9.25589856829762e-07 29.7668678668227 9.82462219968547 3.02982315877507 0.0026463810426819 -39.0261077405077 13.514220166125 -2.88778096410856 0.00414393479130643 POC5 other 0.00961225066317708 1 1 3.02982315877507 -2.88778096410856 0.048412001125428 156.392752458422 107.259093238066 1.45808385785345 0.145798156343148 380.691746904803 160.090804023397 2.37797385819341 0.0179949689790217 SPOCK1 other 1 1 1 1.45808385785345 2.37797385819341 2.29564159224242e-05 0.812287330866031 1.21592641750124 0.668039874102994 0.50458967415483 -6.70734940159943 1.68295031817782 -3.98547083009656 8.34609748097557e-05 FAM151B other 0.21202545745951 1 1 0.668039874102994 -3.98547083009656 7.57235397812044e-05 46.2597478070232 10.6127018929963 4.35890391282467 1.76703697517757e-05 20.5042778697466 34.9870347394206 0.586053605927457 0.558255214254402 TADA1 other 0.661389594603229 1 0.194904178362086 4.35890391282467 0.586053605927457 0.146997567054675 23.7445277429387 12.477122108851 1.90304523236932 0.0579403843537896 37.2548983581812 23.6253511276805 1.57690347782944 0.115815114787302 GUCY1A2 other 1 1 1 1.90304523236932 1.57690347782944 1.20672111808369e-21 75.7139595286604 13.7675656012125 5.49944425338291 7.85443670874438e-08 -93.2822215727338 26.0687976493624 -3.57830931934122 0.000399882429647245 CWF19L2 essential 1.7706218965642e-17 1 0.000982118766061397 5.49944425338291 -3.57830931934122 0.0021615770149251 45.6762650109686 43.2774853191623 1.05542788990894 0.292025853423891 -159.108635411631 59.4747076014288 -2.67523190660981 0.00785176386478331 JMY other 1 1 1 1.05542788990894 -2.67523190660981 2.29025920473959e-08 138.486318176749 23.7558037427879 5.82957830752379 1.35709727054905e-08 22.2756404059936 32.6467554900574 0.682323253003737 0.4955281740201 HOMER1 other 0.000261410185628977 1 0.000174604134828841 5.82957830752379 0.682323253003737 1.38566707574386e-09 54.629341914825 11.1881104809816 4.88280322291134 1.65660534472778e-06 -32.9142890042699 15.5575118045805 -2.11565251678479 0.0351490256332423 XRCC4 other 1.6651561249214e-05 1 0.0195197807769274 4.88280322291134 -2.11565251678479 2.95102774357863e-05 9.96964547430641 3.12779538928726 3.18743531256954 0.00157761532973532 -16.745589189636 7.77450309277566 -2.15391118760973 0.0319959061596108 ZNF547 other 0.269845731176799 1 1 3.18743531256954 -2.15391118760973 0.000264164463235939 19.4972153723692 5.1878199627975 3.75826754054422 0.000203311530885129 -6.48283717512678 13.481360476151 -0.48087410663005 0.630934589312124 ZNF773 other 1 1 1 3.75826754054422 -0.48087410663005 2.39758043256899e-05 47.9697136364185 11.8439859434363 4.05013260447193 6.42826780018729e-05 -35.8810344063404 31.1405353793155 -1.15222920766397 0.250086957100291 ZNF776 other 0.220961012665559 1 0.679532189157799 4.05013260447193 -1.15222920766397 0.00166990259998419 20.4720388423781 5.70207698431362 3.59027752496091 0.000382477413837104 9.09049812385699 14.9273561619175 0.608982463153693 0.542970857342342 ZNF256 other 1 1 1 3.59027752496091 0.608982463153693 4.11714426351354e-14 68.1165963254413 13.1564498286977 5.17742986993807 3.98386658499733e-07 -79.3478946260303 27.2977824008436 -2.90675240431172 0.00390687698745504 SUV39H2 other 5.56761418754935e-10 1 0.00483760919416226 5.17742986993807 -2.90675240431172 4.06985639281891e-14 35.0844089359897 10.5939873430547 3.31172841725083 0.00103326161534188 -106.202426692117 21.98103325847 -4.83154842828845 2.10505502926164e-06 DCLRE1C other 5.50407378564829e-10 0.0314011058714959 1 3.31172841725083 -4.83154842828845 6.84659404751924e-22 88.3582588882056 12.1071554172932 7.2980197117152 2.33657188239985e-12 -71.3422667486465 24.19569732516 -2.94855179372991 0.00342839153547343 RPP38 other 1.00583313152105e-17 1 3.26489189127731e-08 7.2980197117152 -2.94855179372991 1.05944072717464e-09 64.8942922244668 18.1629001672214 3.57290364572843 0.000407542402275976 -108.018266397303 36.2978767386994 -2.97588388364707 0.00314472604491228 NMT2 other 1.27863901362708e-05 1 1 3.57290364572843 -2.97588388364707 0.0722950053768334 1.98937240683287 3.20611904004553 0.620492371613445 0.535385196834744 -15.7101797929203 8.18243349460579 -1.91998869325087 0.0557679797442921 ZNF837 other 1 1 1 0.620492371613445 -1.91998869325087 3.25441582006488e-11 80.3799403677211 21.4457887919989 3.74805241007082 0.000211515237018878 -167.616791627351 40.1429403850683 -4.17549860621814 3.84065619484154e-05 USP12 other 4.1331080914824e-07 0.556280643260849 1 3.74805241007082 -4.17549860621814 2.40873358271394e-07 172.152730708302 32.851261104642 5.24036901231705 2.92476883754604e-07 -421.412501272608 197.070568492073 -2.13838375002992 0.0332473645728037 CCDC50 other 0.00260215488940586 1 0.00357319008883 5.24036901231705 -2.13838375002992 6.11968542893007e-06 22.3607459879764 12.6497099128457 1.76768844044947 0.0780659424967441 -65.3468421265534 17.9609137623356 -3.63828049013781 0.000319845603038215 CAMK4 other 0.0595261801672028 1 1 1.76768844044947 -3.63828049013781 0.00740585885267442 7.85364088344568 5.50426387115141 1.42682855823967 0.154604281776537 -16.5015764246951 8.13434237185895 -2.02863067108939 0.0433236818018779 TRIM36 other 1 1 1 1.42682855823967 -2.02863067108939 0.00246220090555349 602.431425679824 181.510769954851 3.31898446483189 0.00100833748037946 -387.743248713842 644.125165322271 -0.601968793627004 0.547623853506745 ZFP36L2 other 1 1 1 3.31898446483189 -0.601968793627004 1.68956234177084e-10 81.4079601420256 24.6672448908663 3.30024534568792 0.00107572319667567 -197.501867263686 46.0875824132086 -4.2853596765597 2.42091793205299e-05 PAN3 other 2.09928120965027e-06 0.352727742700121 1 3.30024534568792 -4.2853596765597 0.018542206169151 31.748753339906 11.3156608635581 2.8057356722445 0.00532849888481012 -1.20202323288616 40.3199141949885 -0.029812147592208 0.976235513210688 PLEKHH2 other 1 1 1 2.8057356722445 -0.029812147592208 0.00373153062609786 650.288890899744 200.307506790084 3.24645292291131 0.00129311909217658 -142.395278201292 509.966229656219 -0.279224917103401 0.780253732647446 PFKM other 1 1 1 3.24645292291131 -0.279224917103401 5.703989822862e-63 1348.22861345165 64.3116604142994 20.9639838991294 1.41276328120575e-61 -732.370194946163 836.841842258908 -0.87515962749814 0.382158117653388 TMEM123 other 8.75619477707546e-59 1 2.1684503603227e-57 20.9639838991294 -0.87515962749814 3.39746794659308e-05 43.5062961768595 9.5095305264384 4.5750204025218 6.84162155279497e-06 48.8855801230121 59.3628798119643 0.823504187766164 0.410840441100408 IGSF10 other 0.308422140191719 1 0.0777071375966453 4.5750204025218 0.823504187766164 0.420417567432758 5.67511081199257 4.32745938410791 1.31141861962558 0.190665423917157 7.47682164627616 27.6637193646924 0.270275357688125 0.787124296291095 SPEF2 other 1 1 1 1.31141861962558 0.270275357688125 0.0900962500707212 247.306483081822 218.085472800292 1.13398879763206 0.257650702081013 879.349307139084 402.267175144613 2.18598325061686 0.0295433981103086 SPARCL1 other 1 1 1 1.13398879763206 2.18598325061686 5.16927851115475e-13 533.229045181393 68.256146626272 7.81217621470813 8.32175858601096e-14 -219.075584242155 412.790717395288 -0.530718291400841 0.59598561031605 MBNL1 other 6.85032788298227e-09 1 1.18551772816312e-09 7.81217621470813 -0.530718291400841 1.01059925999472e-09 107.138821695972 17.2453665548693 6.21261492790484 1.63623348050867e-09 -199.708513737846 113.251496308116 -1.76340728597979 0.0787951703166687 NADK2 other 1.22100602592562e-05 1 2.16473689471297e-05 6.21261492790484 -1.76340728597979 0.1234890615529 105.135600276355 85.332581177801 1.23206867558937 0.218827969482998 -101.916891353257 126.993202559855 -0.802538161876979 0.42283734536259 GPD1L other 1 1 1 1.23206867558937 -0.802538161876979 0.000136675618179607 3198.77870402224 1051.83527940267 3.04114034455928 0.00255224349945282 -5426.90204964716 2456.12677018774 -2.20953662307599 0.0278473618776568 GJA1 other 1 1 1 3.04114034455928 -2.20953662307599 0.126913491579798 21.3674986127514 11.7658651162143 1.81605843698695 0.0703059322737105 -3.25899629036971 19.8533782308558 -0.164153236415182 0.869715127966375 CCNO other 1 1 1 1.81605843698695 -0.164153236415182 1.24342245959029e-06 124.790116094148 26.9803987375534 4.6252139306027 5.4462334063638e-06 -178.941041943246 93.847684989462 -1.9067176986128 0.0574553927673039 SLC30A6 other 0.0127929920132875 1 0.0622286629011128 4.6252139306027 -1.9067176986128 7.76531619075476e-09 105.85287150828 30.0980290428804 3.51693698472656 0.000502238067899387 -152.572367271765 44.9707066486794 -3.39270557751499 0.000782492202398107 PELO essential 9.05979439975358e-05 1 1 3.51693698472656 -3.39270557751499 0.607364770903916 -8.0315308800132 8.31600855870188 -0.965791560136021 0.334877804973469 -11.6292710980708 28.9324775688043 -0.401945221262686 0.687992666662022 RASGRP3 other 1 1 1 -0.965791560136021 -0.401945221262686 3.28317505089945e-06 144.151664249082 46.0089185486226 3.13312437667366 0.00189006200916513 -179.614996178078 68.7033001912513 -2.61435761714617 0.00936373715827647 SAR1B other 0.0326413263560423 1 1 3.13312437667366 -2.61435761714617 6.40309537561353e-09 83.3880038806011 14.5047421276922 5.74901664203998 2.13770352132376e-08 -41.3495608286324 33.7824342094176 -1.22399589598269 0.221877260438482 GPR180 other 7.49930530391856e-05 1 0.000273241264095604 5.74901664203998 -1.22399589598269 0.286393686084432 -14.8425272476719 11.5890036650386 -1.28074230336542 0.201211662558756 -32.5712197770075 26.1872370156807 -1.24378221946455 0.214490085523079 WDR78 other 1 1 1 -1.28074230336542 -1.24378221946455 0.0163240209547674 -22.0079169183501 47.1399070297676 -0.4668638167753 0.6409170131955 -263.605520072853 94.7053716986588 -2.78342733199564 0.00570058484555842 ANKRD22 other 1 1 1 -0.4668638167753 -2.78342733199564 2.48611995501308e-20 831.69715016175 85.8961059752814 9.68259434718833 1.42399832417847e-19 -173.131445180083 199.845076301695 -0.866328299821188 0.386971630145577 FARP1 other 3.61581286257102e-16 1 2.1087991182759e-15 9.68259434718833 -0.866328299821188 0.000291835040599393 96.3196878744271 43.3080564480861 2.22405935001694 0.0268441901787674 -187.558374526604 86.7852038992686 -2.16117916533678 0.0314252763448679 IFIT5 other 1 1 1 2.22405935001694 -2.16117916533678 0.0234559134481316 13.8045090825892 11.2756250813565 1.22427883004145 0.221750443868628 -38.7808317327666 22.5952744600821 -1.71632488028763 0.0870733898443586 PANK1 other 1 1 1 1.22427883004145 -1.71632488028763 0.0304489986977956 15.491551994132 6.36740919425702 2.43294431400833 0.0155310512288222 -0.204315066665857 12.1054142320508 -0.0168779905213739 0.98654460259655 PRDM8 other 1 1 1 2.43294431400833 -0.0168779905213739 0.416459956284464 -16.9762960543507 34.1172358218355 -0.497587088913155 0.619118995678956 59.5197223673894 64.6432525408127 0.920741454489956 0.357883379683168 BMP3 other 1 1 1 -0.497587088913155 0.920741454489956 0.0774929549267752 173.409983572967 139.067252678243 1.24695052381729 0.213333271388668 -316.746739765224 262.766817763976 -1.20542899008555 0.228933940054485 HNRNPDL other 1 1 1 1.24695052381729 -1.20542899008555 0.409803447156864 -10.4156292408265 11.8469824186149 -0.879179935682242 0.379965496633308 -29.5543667520003 22.7609186103196 -1.29846985782905 0.195063829362515 HHEX other 1 1 1 -0.879179935682242 -1.29846985782905 0.00186245589994021 -132.279248029227 102.045211545553 -1.29628079579391 0.19581575948271 -795.344514058522 224.1887427723 -3.54765589129657 0.000447014979359506 UTRN other 1 1 1 -1.29628079579391 -3.54765589129657 2.89429633858521e-08 616.532085945979 132.016759615173 4.67010467264278 4.44766411267627e-06 -817.79952257077 308.125446860146 -2.65411224845041 0.00835154227983613 PTPRK other 0.000328618406282965 1 0.0510769746699742 4.67010467264278 -2.65411224845041 4.03760292544807e-06 84.1029072888494 16.5492626930552 5.08197306724382 6.36432156550777e-07 -7.87008511453627 53.1458776059556 -0.148084582832335 0.882369282961412 GGPS1 essential 0.039847103271247 1 0.00765436954683619 5.08197306724382 -0.148084582832335 0.000155908347895673 202.996158839652 48.1825436263588 4.21306439140753 3.33904753832265e-05 75.2521199165934 179.940727524592 0.418205044248855 0.676097406760301 ZNF117 other 1 1 0.361418505548044 4.21306439140753 0.418205044248855 0.0216840183898766 -14.1612312109973 16.8512276435915 -0.840367925145369 0.401333526821554 -67.2700497741585 24.3514150835013 -2.76246984183418 0.00607038740929281 PART1 other 1 1 1 -0.840367925145369 -2.76246984183418 0.0114358831779395 2.45273349421333 29.472327433574 0.083221574534329 0.933727555444317 -110.304157181857 40.2252807858774 -2.74216003038028 0.00644824246971237 MARVELD2 other 1 1 1 0.083221574534329 -2.74216003038028 1.55915617738022e-11 90.0164153469239 18.6839639777635 4.81784355044014 2.24730218510042e-06 -82.4517533883974 25.5007921886275 -3.23330164720013 0.00135172508397346 RAD17 essential 1.99494032895799e-07 1 0.026273209846009 4.81784355044014 -3.23330164720013 1.21920528423085e-25 164.25448158846 14.9397509880877 10.9944591258201 4.56602315965202e-24 -166.914504627711 76.8039699738191 -2.17325360504944 0.0304943581754783 MED21 essential 1.82198037675459e-21 1 6.86410261590487e-20 10.9944591258201 -2.17325360504944 1.03879816834631e-05 413.881973069525 87.1220091988075 4.75060179253981 3.0709542655801e-06 -291.226667888003 469.091200634742 -0.620831658095345 0.535153708891534 PLOD2 other 0.0990286293884533 1 0.0356261404349947 4.75060179253981 -0.620831658095345 0.000263552383028561 11.2419978986782 11.4345851045381 0.983157481963785 0.32627734853676 81.5607761919379 21.1419655056942 3.85776696920497 0.000138543045179346 STK32B other 1 1 1 0.983157481963785 3.85776696920497 0.00777980569188053 -11.2092089911017 3.99033657212888 -2.80908860405264 0.00527466360950025 -20.3667480656039 7.39434619574341 -2.75436766503144 0.00621800349647424 JAKMIP1 other 1 1 1 -2.80908860405264 -2.75436766503144 0.0011708252475013 79.0851016597695 21.3597875556081 3.70252285767727 0.00025156981989599 -11.4009818865593 124.01161885978 -0.0919347879770069 0.926807738587925 ZIC1 other 1 1 1 3.70252285767727 -0.0919347879770069 1.28649893707337e-06 134.125507750975 37.0431496343548 3.62079113344572 0.000341657991261239 -83.9077700328727 68.676401827781 -1.2217845984897 0.222694018159583 ADGRA3 other 0.0132149170816177 1 1 3.62079113344572 -1.2217845984897 9.1666743396521e-10 170.689275773186 34.6878315608654 4.92072487937691 1.38437806095731e-06 -103.636815046876 48.6907787044598 -2.12846904084086 0.034064277256245 SREK1IP1 other 1.11008426253187e-05 1 0.0163910362417346 4.92072487937691 -2.12846904084086 0.302854598581854 42.5729209613966 68.0001982152028 0.626070542127898 0.53172062149735 -105.132938950479 126.855333228117 -0.828762467254134 0.407864368558021 LGI2 other 1 1 1 0.626070542127898 -0.828762467254134 1.21294258570774e-16 144.462780235256 20.6738161593328 6.98771717431764 1.6367967766431e-11 -71.9137740737879 29.0195195921796 -2.47811731842617 0.0137248778839132 CWC27 other 1.70260750755796e-12 1 2.2550149191812e-07 6.98771717431764 -2.47811731842617 0.212766520700779 78.561397171758 45.9906391122647 1.70820407561606 0.0885682376122161 -70.9610788749396 144.251146839553 -0.491927311703581 0.623108011877926 MR1 other 1 1 1 1.70820407561606 -0.491927311703581 3.10258240940535e-08 86.6457260042204 25.5304327102126 3.39382128723422 0.000775921732663721 -120.910011667584 36.1607083844689 -3.34368481894884 0.000924866747658045 SRP19 essential 0.00035170874193019 1 1 3.39382128723422 -3.34368481894884 3.68662222672089e-07 53.0828388983536 36.9486190198811 1.43666638446734 0.151792820842808 -222.11131265122 50.4292909365554 -4.40441078044616 1.44975222333456e-05 CENPH essential 0.0039387871870286 0.212620661074247 1 1.43666638446734 -4.40441078044616 8.14790049482121e-11 134.985292381784 24.7524903862013 5.45340247690932 9.96049881962854e-08 -102.912872707099 55.4306049554029 -1.85660742454277 0.0642945992157911 CDYL other 1.02223559608027e-06 1 0.00124048052299654 5.45340247690932 -1.85660742454277 0.000193351474519354 235.437865946035 174.015587979817 1.35296997630662 0.177032399242833 -1951.48871964951 555.949072293886 -3.51019331968219 0.000512876497859142 CARHSP1 other 1 1 1 1.35296997630662 -3.51019331968219 0.0681957425022554 -23.6839112132345 10.2360863049455 -2.31376626844108 0.0213138152970771 -12.213272241383 18.5980297108545 -0.656697103470852 0.511847673228136 BANK1 other 1 1 1 -2.31376626844108 -0.656697103470852 0.00105358932848735 59.6119932921615 31.1099102901805 1.9161737445118 0.0562336785167396 -267.278151707602 100.943229043466 -2.64780663587165 0.00850287146974931 TXNDC11 other 1 1 1 1.9161737445118 -2.64780663587165 0.337768323684615 36.1525919500986 34.7526865260596 1.04028193397334 0.299006732689879 272.442167863142 239.810464149433 1.13607289335537 0.2567896433727 DAB2 other 1 1 1 1.04028193397334 1.13607289335537 0.47508853074464 -49.6398400404909 41.6713997729144 -1.19122084477603 0.234449695150728 -62.201441740311 138.627551518005 -0.448694657441398 0.653955624078002 BCL2L11 other 1 1 1 -1.19122084477603 -0.448694657441398 2.92997692265776e-07 163.063779845202 29.2592324148674 5.57307100654987 5.31914688789931e-08 15.6383000794286 97.3362011133049 0.160662732884189 0.872460418794767 ANAPC1 essential 0.00314855320108803 1 0.000669414635842128 5.57307100654987 0.160662732884189 4.61532802971269e-11 1661.89102409305 356.765566518371 4.65821587075016 4.68402687882641e-06 -1588.57052632943 507.831984291561 -3.12814193565521 0.00192089572164139 CAST other 5.83700535917763e-07 1 0.0537070521926236 4.65821587075016 -3.12814193565521 1.74496034497749e-06 175.684164650583 52.2644465720463 3.36144695244027 0.000870836854032876 -232.837345269704 92.363603368549 -2.52087767018614 0.0121997203004724 SCOC other 0.0177148374222115 1 1 3.36144695244027 -2.52087767018614 0.116456701446195 -33.0081352967743 23.7991486061823 -1.38694605605344 0.166438838714081 -82.1558944942912 42.0587084824556 -1.95336227522444 0.0516617066567437 CLGN other 1 1 1 -1.38694605605344 -1.95336227522444 1.00771690054024e-05 39.768938059978 15.0685983413603 2.63919292020812 0.00871715800674804 -56.9693865759268 20.9392971296542 -2.72069240066548 0.00687075739611894 CETN3 other 0.0961966553255709 1 1 2.63919292020812 -2.72069240066548 3.83261465464099e-06 478.281913484206 101.272350772353 4.7227294502062 3.50898673664066e-06 -4.39223086742764 179.211213474876 -0.0245086832585027 0.980462375950112 SMARCA5 other 0.0379198893930179 1 0.0405673956623026 4.7227294502062 -0.0245086832585027 0.675669854682178 -6.18807257806155 7.41190729066528 -0.834882620004563 0.404408613121584 -10.3094674868967 16.5777348933155 -0.62188637671204 0.53446078328496 BMP6 other 1 1 1 -0.834882620004563 -0.62188637671204 0.0116804820056194 16.7712559838252 5.5840318545656 3.00343128775542 0.00288005291095964 8.69938553220903 17.5874133282259 0.494637009425796 0.621195788212046 RGPD3 other 1 1 1 3.00343128775542 0.494637009425796 0.000163589580345353 74.2041395683875 17.7395680673188 4.18297329939459 3.73464051481144e-05 -10.2918040000247 71.7090267846531 -0.143521735846892 0.885969914735685 RASSF3 other 1 1 0.402818325927562 4.18297329939459 -0.143521735846892 0.000516778744690533 1008.78467212545 256.252733812625 3.93667867310669 0.000101597727423265 -158.591003456197 839.812662926436 -0.188840929003816 0.850338333269846 HNRNPU essential 1 1 1 3.93667867310669 -0.188840929003816 0.000317781949879388 378.251933216815 93.8622523721426 4.02986209746098 6.9838209890451e-05 27.3845999248711 305.298022376634 0.0896979276566942 0.928583553037537 RANBP2 other 1 1 0.735815379405792 4.02986209746098 0.0896979276566942 4.45501136717724e-11 296.800227257363 41.5211893730787 7.14816294375711 5.99308657358884e-12 -47.9515495583997 131.926668238169 -0.363471238975216 0.716492894579206 AHCTF1 essential 5.6378168851628e-07 1 8.31780485548395e-08 7.14816294375711 -0.363471238975216 0.884763883470274 -2.50819931854395 25.8107245833424 -0.0971766333194178 0.922646958884126 39.7775938944456 85.5651758099081 0.46488064236338 0.642333098200453 MERTK other 1 1 1 -0.0971766333194178 0.46488064236338 1.31936637524864e-07 221.265794555113 39.4416966065206 5.60994616338419 4.38344359871665e-08 -63.358749261453 130.753233737422 -0.484567359830579 0.62831477499208 TMEM87B other 0.00144562973735994 1 0.000553497423209952 5.60994616338419 -0.484567359830579 0.00592116168300006 4.75183418239696 1.4903673953572 3.1883642900401 0.0015745644183478 6.89931508486935 8.44531760932864 0.816939682321529 0.414580317011921 PTPRR other 1 1 1 3.1883642900401 0.816939682321529 0.423914109026354 -12.629674195978 47.4068770836883 -0.26641017027303 0.790095992818637 -162.793169271256 124.161051136526 -1.31114522453785 0.190754666817778 NR4A2 other 1 1 1 -0.26641017027303 -1.31114522453785 0.00513257745833084 184.175759541573 64.4524398551358 2.85754519077212 0.00454985112627075 -181.381316899124 175.851787839321 -1.03144425841639 0.303113899496488 PLA2R1 other 1 1 1 2.85754519077212 -1.03144425841639 0.680783993272972 0.795339291449722 1.55642335336226 0.51100447042997 0.609705885896894 -2.67817478909389 4.36462563971061 -0.613609278359889 0.539916388206444 SCN3A other 1 1 1 0.51100447042997 -0.613609278359889 0.344235797284034 -9.04158730725936 10.066712343362 -0.898166849201902 0.369771888585224 -54.8973444333155 41.2666409085774 -1.3303080460301 0.184364076439721 CD96 other 1 1 1 -0.898166849201902 -1.3303080460301 0.188675059710842 4.54771264854375 2.9044368901588 1.56578118944602 0.118391275338601 -4.39054667378956 8.8064699763203 -0.498559205401857 0.618433532474926 SLC25A27 other 1 1 1 1.56578118944602 -0.498559205401857 0.554312139357506 -63.1792538519591 58.2290250540803 -1.08501308056045 0.278740319146602 -56.1882017956887 139.992436133866 -0.401365983387555 0.688421118141338 ADGRF1 other 1 1 1 -1.08501308056045 -0.401365983387555 0.000921500538699973 106.217794498977 40.8733266694058 2.59870686225504 0.00979763236639511 -170.277266175215 95.5299661486657 -1.78244872305541 0.0756391354779295 ADGRF4 other 1 1 1 2.59870686225504 -1.78244872305541 2.95939196379314e-13 296.278778386844 37.7343295436416 7.85170379254209 6.44390088415605e-14 -112.1677740601 221.117777180824 -0.507276147084152 0.612314901659895 FAM49B other 3.94161415657609e-09 1 9.19093583107178e-10 7.85170379254209 -0.507276147084152 1.92198698562332e-07 190.714086835465 33.6792351120822 5.66266087103168 3.35034399746417e-08 -18.6865021923754 197.35550346856 -0.0946844747876625 0.924625460445982 ASAP1 other 0.00208747006508549 1 0.000424790115438482 5.66266087103168 -0.0946844747876625 1.14868431157523e-14 277.054300353594 46.3455158922241 5.9780173986601 6.06183513096852e-09 -124.841025466122 82.7959553207015 -1.50781550840936 0.132594551988608 TRAPPC8 essential 1.5711704013726e-10 1 7.89372170754721e-05 5.9780173986601 -1.50781550840936 2.42356906009689e-14 79.4071674661043 24.6040702518067 3.22739963971096 0.00138070623996421 -204.474147225233 43.9786786882003 -4.64939269037416 4.90398286648672e-06 INO80C other 3.29508449410773e-10 0.072726065909998 1 3.22739963971096 -4.64939269037416 1.48476594989396e-14 489.19066606402 58.4621780850993 8.36764352761438 1.90094499402185e-15 82.2748642311402 342.978036365576 0.239883769535156 0.810575404120596 LPCAT1 other 2.02566618544033e-10 1 2.748956555855e-11 8.36764352761438 0.239883769535156 8.24333355675836e-10 127.672038142402 19.1024432855155 6.68354493894558 1.05521742788382e-10 83.8661087185752 112.24148638966 0.747193496951956 0.455502378140058 PLEKHG4B other 1.00016366044149e-05 1 1.43309078880902e-06 6.68354493894558 0.747193496951956 0.000180984918682126 163.468987830113 44.696808593334 3.6572854522435 0.00029821620216278 -135.197627557446 131.513040557772 -1.02801689462921 0.304723177568589 NMRAL1 other 1 1 1 3.6572854522435 -1.02801689462921 0.000648805370524916 67.6432592150948 20.8614624388134 3.24249843046682 0.00131060998036531 -72.3999690731185 61.3814373364292 -1.17950918412512 0.239077151819885 UBALD1 other 1 1 1 3.24249843046682 -1.17950918412512 0.666183245739702 -7.71159698332893 14.6787655426054 -0.525357323880258 0.599699775298877 -36.7113701659547 43.3588880305712 -0.846686154406693 0.39780479911501 C16orf89 other 1 1 1 -0.525357323880258 -0.846686154406693 8.84740726589642e-09 56.1757469737507 9.63060280325449 5.83304577308152 1.33184271106474e-08 -14.5135667464735 28.7818946570185 -0.504260296947974 0.614425491281608 TMEM251 other 0.000102974973167768 1 0.00017138152005981 5.83304577308152 -0.504260296947974 0.00889349064522384 64.9190807325606 23.6314023164368 2.74715312545824 0.00635533893944274 -44.1062159502286 57.8082164192402 -0.762974862091555 0.446045785195027 ING1 other 1 1 1 2.74715312545824 -0.762974862091555 0.481149673152283 2.08362172054877 2.40854299788103 0.865096335162746 0.38764217699342 6.0358798707024 5.89719671897348 1.02351679252665 0.306846454081702 TEX29 other 1 1 1 0.865096335162746 1.02351679252665 0.000775122027541475 150.965107334898 39.4628245962604 3.82550182049573 0.000157446104134303 71.471894949263 96.7657712843575 0.738607195505469 0.460697260221875 ADPRHL1 other 1 1 1 3.82550182049573 0.738607195505469 0.240193209253331 58.2817941859021 40.3749901623047 1.44351228202442 0.149854453242999 -2.50232422186385 60.0866542798027 -0.0416452580336956 0.966807465564237 CMTM7 other 1 1 1 1.44351228202442 -0.0416452580336956 5.57110787628331e-07 27.4411238463037 7.77380838118978 3.52994600596315 0.000476612684221935 -21.6248365781501 11.569095986408 -1.86918983156126 0.0625096637975786 FBXL2 other 0.00586971925845209 1 1 3.52994600596315 -1.86918983156126 1.48866614050271e-19 386.569381211358 71.1428939320958 5.43370335174065 1.09536753009951e-07 -478.565707098443 105.875901269037 -4.52006265224018 8.71386049714883e-06 UBP1 other 2.15395103869338e-15 0.128424876006979 0.00136197998692574 5.43370335174065 -4.52006265224018 0.000481433856886815 295.398514291916 75.5263012207124 3.91120059525575 0.000112382258449142 -84.4000678199061 311.611050419276 -0.2708506893653 0.786682144475862 RMND5A other 1 1 1 3.91120059525575 -0.2708506893653 0.00334515817391979 -127.574502427952 40.3644351374396 -3.1605670188017 0.00172665078279677 -254.529694267861 166.538064614091 -1.52835746504962 0.127420992982082 CD8A other 1 1 1 -3.1605670188017 -1.52835746504962 0.00221319106233753 81.8480589626656 24.1609256119632 3.38762099917806 0.000794201343409801 -70.201166194317 98.4572996304193 -0.713011289745222 0.476364961096206 RPIA other 1 1 1 3.38762099917806 -0.713011289745222 6.19991215025704e-13 148.362602201048 19.228311485374 7.71584142028799 1.62268963272102e-13 181.702976141334 73.869687123852 2.45977725391858 0.0144426379613897 PTPRD other 8.20186378357504e-09 1 2.30194751297804e-09 7.71584142028799 2.45977725391858 0.0961249473135473 24.3485624485237 13.9556473671983 1.74471035329777 0.0820105708923823 -53.9593963893173 52.2785214377323 -1.03215230472015 0.302792577530557 LURAP1L other 1 1 1 1.74471035329777 -1.03215230472015 0.129725015331953 21.6298130219495 35.42527437775 0.610575737291532 0.541915248356958 -135.473466240345 77.4626962526961 -1.74888653240791 0.0812724382192206 CNKSR3 other 1 1 1 0.610575737291532 -1.74888653240791 5.69527436780399e-25 115.129726560924 10.060637825302 11.4435812679171 1.22617296418811e-25 16.1280192471303 39.2612605203095 0.41078709734211 0.681504450681726 GTF2E1 essential 8.49051502752218e-21 1 1.84980453377418e-21 11.4435812679171 0.41078709734211 5.72096481808491e-07 213.396316692844 48.5442778948757 4.39591082506081 1.50427952059179e-05 -132.77904133283 127.182425271839 -1.04400463388734 0.297273739030882 CFDP1 essential 0.00602417595344341 1 0.166749384857599 4.39591082506081 -1.04400463388734 2.03813553967179e-09 128.673235967952 42.0734673267783 3.05829883162627 0.00241388185219655 -405.139378070309 107.791994427193 -3.75852938080626 0.000203107966335417 ZDHHC7 other 2.43434908858399e-05 1 1 3.05829883162627 -3.75852938080626 4.08499346299572e-05 16.8187145828491 3.74930383333316 4.48582332360541 1.0160041800896e-05 -0.498573749336023 15.7059340934472 -0.0317442914486721 0.974695887529312 C7orf31 other 0.368221310754434 1 0.113955028838849 4.48582332360541 -0.0317442914486721 0.00623829910206945 -353.115116623967 248.529285616609 -1.42081894191213 0.156352284833162 -1704.95943702722 532.194045092165 -3.20364245475907 0.0014949701749687 TMPRSS11D other 1 1 1 -1.42081894191213 -3.20364245475907 0.353613283874348 7.50214846336192 13.4999922562726 0.555715019753153 0.578797672074005 -66.9736698350553 55.4165387767906 -1.20855021467175 0.227736418908218 JAZF1 other 1 1 1 0.555715019753153 -1.20855021467175 3.26002600105917e-11 474.454611379978 139.475270543289 3.40171135378956 0.00075462885574702 -1439.93306463515 356.106285449241 -4.04354857937601 6.60247720634223e-05 CMIP other 4.13990701874504e-07 0.948379825918998 1 3.40171135378956 -4.04354857937601 0.123367418378166 20.8794448878738 17.7782593986343 1.17443695806788 0.241093287646385 -29.7476871250606 30.9655304930264 -0.960670999379775 0.337442931112063 PID1 other 1 1 1 1.17443695806788 -0.960670999379775 1.99554366907301e-13 706.593024896365 156.24925067138 4.52221704654734 8.64884631155745e-06 -1036.38445707017 272.462352498394 -3.80377122771953 0.000170870846534465 TRIP12 other 2.66724366808299e-09 1 0.0975849329333027 4.52221704654734 -3.80377122771953 7.61784811385506e-06 2.4040876765709 5.98366869556351 0.401774864031721 0.688118761490758 -43.7853866815113 10.4281072935571 -4.19878559444471 3.48492820838145e-05 FBXO36 other 0.073527469994929 0.505523685907813 1 0.401774864031721 -4.19878559444471 1.3080837661947e-10 286.119575341768 49.6668929771945 5.76077056950484 1.96669431736776e-08 -352.56294205722 147.904434458452 -2.38372124100349 0.0177213472729989 CEBPG other 1.62882590566564e-06 1 0.000251894208168463 5.76077056950484 -2.38372124100349 8.49674198999587e-10 339.041794394569 55.9676210670444 6.05782035989034 3.87121544345096e-09 -199.702681373623 167.268698446206 -1.19390348121737 0.233400016995178 KCTD15 other 1.0306548033865e-05 1 5.06896950165468e-05 6.05782035989034 -1.19390348121737 0.000829298030889008 11.662361712016 3.87997640181628 3.0057816090213 0.00285917043457992 -18.0284337822751 12.2792694624327 -1.46820084349736 0.143035001781267 ZNF599 other 1 1 1 3.0057816090213 -1.46820084349736 0.029115732778814 -11.5873964127057 5.37776078845157 -2.15468795815332 0.0319344967602413 -24.8818802107808 11.3907734929754 -2.18438899045137 0.0296613568694511 MCOLN2 other 1 1 1 -2.15468795815332 -2.18438899045137 0.210485400992451 8.10341799019251 6.23458297063261 1.29975301128606 0.194624063805334 -16.6370071412888 20.167419152563 -0.824944779271594 0.410019382924213 LGI4 other 1 1 1 1.29975301128606 -0.824944779271594 0.516639051137569 -36.3226267887886 32.3504238608905 -1.12278673519021 0.26236977218373 -40.0798389102343 68.7443348724642 -0.583027517606959 0.560285412294597 DDAH1 other 1 1 1 -1.12278673519021 -0.583027517606959 0.000168886185866142 117.06232858008 56.8546550924149 2.05897526578607 0.0403132442292242 -203.969523889272 79.8710473179433 -2.55373543653847 0.0111250587756364 SREK1 other 1 1 1 2.05897526578607 -2.55373543653847 1.47476037190811e-09 149.049816018858 41.9962626800779 3.54912095760283 0.000444440049009397 -216.937192891402 59.4022137582349 -3.65200518913872 0.000303873901460115 CHD1 other 1.7701548744013e-05 1 1 3.54912095760283 -3.65200518913872 0.42559072832187 -4.69185316849073 3.61831760709898 -1.29669467359237 0.195670505239577 -4.36055421356926 7.68888959003887 -0.5671240512048 0.571027509011709 CLCA3P other 1 1 1 -1.29669467359237 -0.5671240512048 0.135797854460837 19.4928686543111 10.8735003355351 1.79269490530179 0.0739811123853665 -17.4912570507654 25.8546190890467 -0.67652348659724 0.499204789509845 DGKE other 1 1 1 1.79269490530179 -0.67652348659724 0.0254823228447108 76.7023656444652 35.989347135222 2.13125193286427 0.0338301850755549 -73.5957680199416 76.4770113042026 -0.962325367648061 0.336612797620261 HS2ST1 other 1 1 1 2.13125193286427 -0.962325367648061 0.183788454174819 50.3356656865976 64.8972500464748 0.775620933869321 0.438554742935162 -241.939077708548 154.255466693874 -1.5684311414952 0.11778450247057 MSI2 other 1 1 1 0.775620933869321 -1.5684311414952 0.0517926856843524 108.193196417631 44.3080770608279 2.44183913170277 0.0151642022513731 83.3237047685154 165.502111454489 0.503460070909296 0.614993846102561 CACNA2D1 other 1 1 1 2.44183913170277 0.503460070909296 2.07998874376476e-08 22.0988311612412 6.67275473940672 3.31180030201531 0.00103334825799515 -64.4939950908774 15.5648316707782 -4.14357163990152 4.38501227053378e-05 ZUFSP other 0.000237867512736938 0.633853523705658 1 3.31180030201531 -4.14357163990152 0.0194404281308994 9.71761277390732 4.084139816369 2.37935359973713 0.0179345210848798 17.771647433153 9.59711581652871 1.85176961213135 0.064988614562624 GDPD1 other 1 1 1 2.37935359973713 1.85176961213135 7.45720649904592e-11 181.123168948519 36.9318455999272 4.90425447215875 1.4968397512703e-06 -327.991988465725 85.8213704087746 -3.82179854392293 0.000159268345485257 NUS1 essential 9.36774280410148e-07 1 0.0176851616612586 4.90425447215875 -3.82179854392293 0.0619312020343903 17.3620060671067 11.5630993242604 1.5015010751209 0.134224561185293 -58.4480861281744 42.7327070182352 -1.3677599713782 0.172359129060315 SEMA3D other 1 1 1 1.5015010751209 -1.3677599713782 6.82786371460179e-28 380.012490342518 33.5741333697242 11.3186090660258 3.67544940166858e-25 -244.436371245287 111.156025809886 -2.19903841887398 0.0285994439660786 PPP2R5E other 1.02711553858755e-23 1 5.53963733819488e-21 11.3186090660258 -2.19903841887398 0.000460956033221385 119.13352967027 33.7051153142687 3.53458306133835 0.000468638187459404 -101.173979040453 62.9591317071354 -1.60697862720026 0.109045293300871 SLC5A10 other 1 1 1 3.53458306133835 -1.60697862720026 0.378088094769329 4.00180506700597 4.71086200193881 0.84948467294499 0.396246730437353 13.2314143876884 10.0275100198436 1.31951146012364 0.187941458963471 AK5 other 1 1 1 0.84948467294499 1.31951146012364 0.00143557644490846 65.7635585378146 18.3890791082821 3.57622902977213 0.000410056346039906 35.8078503020106 39.5341937328945 0.90574378584624 0.365844689262777 CABYR other 1 1 1 3.57622902977213 0.90574378584624 1.36015668414707e-17 308.014241759306 39.3100606821916 7.83550664674612 9.4966620043131e-14 -91.4688849395614 83.859955927747 -1.09073375877243 0.276317849544732 IMPACT other 1.93155850715726e-13 1 1.35203976955406e-09 7.83550664674612 -1.09073375877243 2.41650211576132e-05 60.5808332253061 31.540341748037 1.92074117995492 0.0557834049027874 -203.898854674323 68.9446443116629 -2.95742848063153 0.00336771391430824 ANKRD29 other 0.222608174903933 1 1 1.92074117995492 -2.95742848063153 0.347050823296797 0.129533244981214 9.18577804483444 0.0141014995516963 0.9887579310929 -31.4529821205452 21.9597347649714 -1.43230245980552 0.153048849942332 SDHAF4 other 1 1 1 0.0141014995516963 -1.43230245980552 0.423720155938937 -55.8772420921581 43.1410272520284 -1.29522279953431 0.196235896852332 -74.778522793643 86.3172232239171 -0.866322154498166 0.387003541316573 CHST9 other 1 1 1 -1.29522279953431 -0.866322154498166 0.117480263060315 456.485902129396 247.256700239541 1.84620235442418 0.0657890989854462 888.032124394907 466.447123386668 1.90382163351613 0.0578330925194286 THY1 other 1 1 1 1.84620235442418 1.90382163351613 0.315149507166571 -3.09858726873727 11.0348694812025 -0.280799630119378 0.779045548864813 -41.427786583915 28.3645867566518 -1.46054610064783 0.145121159572482 DNAAF1 other 1 1 1 -0.280799630119378 -1.46054610064783 6.35223054685689e-05 56.2482542232068 31.5451693468588 1.78310198955416 0.0755174760356182 -229.698236962631 80.5390243956426 -2.85201166374023 0.00462687336303099 C16orf74 other 0.559123332734344 1 1 1.78310198955416 -2.85201166374023 2.7261163517581e-09 59.588393995386 15.8489635488492 3.75976598165074 0.000202149182731355 -51.7710294657322 29.8024224205969 -1.73714165697995 0.0833243751899517 TBCEL other 3.24407845859214e-05 1 1 3.75976598165074 -1.73714165697995 0.0153777833740295 37.9996217332823 14.5464794952788 2.61228991836929 0.00941800296126484 1.41244279517304 37.1431255981035 0.0380270311781505 0.969689841703828 JPH3 other 1 1 1 2.61228991836929 0.0380270311781505 5.16944676233137e-05 335.003749226918 78.6556633200346 4.25911797175815 2.71982824767934e-05 -522.694376519896 485.06499535375 -1.07757595688533 0.282055477925852 ANKH other 0.460701095458972 1 0.296162097889803 4.25911797175815 -1.07757595688533 2.8401598881469e-11 143.169942017396 21.204913466974 6.75173432046203 7.10475401685334e-11 -257.669886062559 130.828252826084 -1.96952783895304 0.0497740927502338 OTULIN other 3.61381944167812e-07 1 9.67738544635593e-07 6.75173432046203 -1.96952783895304 9.79545707195072e-10 126.670183798502 27.4051571513117 4.62212944443702 5.51649535809214e-06 -44.1072157930568 51.403973725342 -0.858050703020108 0.391506678141742 UBASH3B other 1.18427075999884e-05 1 0.0630038934847704 4.62212944443702 -0.858050703020108 0.171490650166624 40.2477513302797 25.5132974768826 1.57752056027833 0.115666901200441 9.40991676602136 47.244398370303 0.199175290417843 0.842252518467258 ROBO4 other 1 1 1 1.57752056027833 0.199175290417843 0.0118986507481219 40.3339428370183 14.3795585803016 2.80494999980537 0.00534118566646992 25.3363346403854 26.6274320115789 0.951512508955726 0.342064641748824 ROBO3 other 1 1 1 2.80494999980537 0.951512508955726 1.372817735526e-28 120.095689646366 19.9987057988466 6.00517307741448 5.2019173074824e-09 -176.51045082356 37.0327208588891 -4.76633762601841 2.85544154219054e-06 TBRG1 other 2.06801263679637e-24 0.0424889701477952 6.78434055241854e-05 6.00517307741448 -4.76633762601841 0.0902997871672346 20.4906509528543 10.8075421066579 1.89595846591531 0.0588690629976856 6.61238338316875 20.0129295381523 0.330405569587552 0.741310425167655 NRGN other 1 1 1 1.89595846591531 0.330405569587552 0.00243345485506019 44.5890475955942 12.9477665465998 3.44376363561357 0.000652346103362883 -24.6731533989086 79.3850433046899 -0.310803551548242 0.756158173273439 RETREG1 other 1 1 1 3.44376363561357 -0.310803551548242 0.76903671279234 1.40498263549209 4.54696242143788 0.308993676496626 0.75753323268363 -16.5400207884954 26.6137455175263 -0.621484141629111 0.534736399979022 CDH12 other 1 1 1 0.308993676496626 -0.621484141629111 0.199767039097231 -4.45556274074282 2.96259952443648 -1.5039368986567 0.133586991814909 6.81295946837701 12.3914177457673 0.549812750095058 0.58283253687864 GPR15 other 1 1 1 -1.5039368986567 0.549812750095058 6.28170522224807e-36 590.12423154266 43.0257963591825 13.715591144816 6.21567258357924e-34 -183.093712084086 178.659598553536 -1.02481878145059 0.30623009220183 TOMM70 other 9.56452437139492e-32 1 9.47144188285804e-30 13.715591144816 -1.02481878145059 0.673475901231056 -17.1075319351566 24.8896862958159 -0.687334172549714 0.492374719721184 -73.7195354133456 101.646551137843 -0.725253681390274 0.468831445713547 ABI3BP other 1 1 1 -0.687334172549714 -0.725253681390274 0.695599058571189 -2.0815159784939 4.64995887882558 -0.447641803451738 0.654714605719178 -19.0301162950005 25.5297284810327 -0.745410054366184 0.456571019753197 ANGPT1 other 1 1 1 -0.447641803451738 -0.745410054366184 0.0242497589211567 66.6842260864884 33.3857574376795 1.99738544829982 0.0466350321131333 -125.660386486414 78.4396088540907 -1.60200169687435 0.110148070966677 PITPNC1 other 1 1 1 1.99738544829982 -1.60200169687435 1.36062095998799e-08 142.620480187055 26.5685958344279 5.368009701222 1.53514148197887e-07 -114.963849625438 64.6385768999212 -1.77856405786028 0.0762635652765348 CC2D1B other 0.000156838778057816 1 0.00189789541417047 5.368009701222 -1.77856405786028 0.00024073614599481 316.157967716279 100.420442954664 3.14834269212508 0.00179669934339631 -515.19855914008 282.526445130936 -1.82354101012142 0.0691542124554244 CERS3 other 1 1 1 3.14834269212508 -1.82354101012142 0.00794109667128079 98.116308087029 31.3753604581014 3.12717707954473 0.00192806606654491 13.0008844062761 73.859900833796 0.17602087546166 0.860389580327706 PRKCA other 1 1 1 3.12717707954473 0.17602087546166 2.40426456984185e-10 208.455602259059 34.9928667465388 5.95708844802428 6.78327906121425e-09 -124.73357786246 77.4700467230364 -1.61008780991698 0.108367745822006 LRRK1 other 2.97527740517929e-06 1 8.81826277957853e-05 5.95708844802428 -1.61008780991698 0.320789138414627 5.48518345959698 6.73985134927677 0.813843388428081 0.416343646405049 21.6001111434279 15.8661046446582 1.3613997655499 0.174351210938264 CEP112 other 1 1 1 0.813843388428081 1.3613997655499 0.227677545813003 -2.99774915542807 3.38918611884583 -0.884504140613245 0.377092393109556 10.7703330334003 7.95007956116421 1.3547453142498 0.176460396637685 ABCA9 other 1 1 1 -0.884504140613245 1.3547453142498 0.478712007071796 -5.09111003949414 4.279105378295 -1.18976037966204 0.235028107463494 0.932940726412613 10.0375804146265 0.0929447822956573 0.926005956794748 ABCA6 other 1 1 1 -1.18976037966204 0.0929447822956573 0.570734928802876 0.302349984105373 3.54471045109047 0.0852961019742417 0.932079666184336 8.80384381213057 8.31489600136102 1.05880383960178 0.290492710889911 ABCA10 other 1 1 1 0.0852961019742417 1.05880383960178 0.641568759738268 13.0406445147287 21.9019586744261 0.595409968057133 0.551992949329747 -33.3294261221893 51.3758489210131 -0.648737233976046 0.51697644128148 ABCA5 other 1 1 1 0.595409968057133 -0.648737233976046 0.848663272113363 5.90019976431592 10.6856546266857 0.552160814703959 0.581224812805237 -0.327027418755155 25.4191917371843 -0.0128653744043626 0.989743241799339 ENPP3 other 1 1 1 0.552160814703959 -0.0128653744043626 0.527644317031547 -18.6995180163738 17.0526901417328 -1.09657290790798 0.273660463467958 -27.4721568646407 33.9582702636744 -0.808997532893424 0.419123329049441 C4orf19 other 1 1 1 -1.09657290790798 -0.808997532893424 0.00828961430572939 -31.3217467564866 189.738516608432 -0.165078484412978 0.868986767422002 925.817094406528 363.349932110076 2.54800403850372 0.0113027084039105 UCHL1 other 1 1 1 -0.165078484412978 2.54800403850372 0.000156028242237557 188.88139800438 44.999061815501 4.19745191085996 3.50166314333611e-05 -115.917034216263 147.355572656729 -0.786648459412501 0.432069856064515 MIA3 other 1 1 0.378424735900334 4.19745191085996 -0.786648459412501 0.62227627938182 5.91525441711581 6.22960126136471 0.949539813053774 0.343062697634786 -5.1989330046644 20.3996799990009 -0.254853654808263 0.798999839795413 DISP1 other 1 1 1 0.949539813053774 -0.254853654808263 8.75796158362582e-07 63.8723335282363 11.8711472604825 5.38046846919835 1.44943525662707e-07 -52.0738241565205 85.3978356030568 -0.609779203287636 0.54244629414705 TNIK other 0.00910740425081248 1 0.00179338624302467 5.38046846919835 -0.609779203287636 2.61513123909917e-05 139.834327405228 36.771856379884 3.80275409434387 0.000171448589746043 25.6520516932033 70.8993808041863 0.361809248575111 0.717734121469439 FAM167A other 0.240199283194262 1 1 3.80275409434387 0.361809248575111 1.44178723463587e-20 102.58117414004 15.0736977807564 6.80530919699067 5.00025332541463e-11 -44.8967038969404 29.0634181762362 -1.54478401765042 0.12338994649718 NEIL2 other 2.10082817958792e-16 1 6.82634583985605e-07 6.80530919699067 -1.54478401765042 0.400988775791668 -5.84427638886774 11.182611542466 -0.522621783531877 0.601604847300083 24.7102871869074 21.8207638550517 1.13242081491967 0.258318814332106 PGM5 other 1 1 1 -0.522621783531877 1.13242081491967 0.679840452905464 10.740628282563 13.622516663242 0.78844669807193 0.431019161545293 -19.0713637017308 45.9612046666318 -0.414944817918944 0.678460354317737 WNT3A other 1 1 1 0.78844669807193 -0.414944817918944 0.511400203512443 380.844800420167 330.771873458618 1.15138205808727 0.250434635941915 107.897246398559 1115.99597562017 0.0966824690730622 0.923039084819914 OBSCN other 1 1 1 1.15138205808727 0.0966824690730622 8.97060527861451e-12 72.8093948765552 30.3275739312731 2.40076555551566 0.0169349323424292 -226.407854239219 57.3588519690411 -3.94721732508559 9.73682585903317e-05 LONRF1 other 1.15523454777998e-07 1 1 2.40076555551566 -3.94721732508559 0.000291479399729018 819.025986128534 206.07661465246 3.97437616834782 8.72550542256445e-05 -740.213038774957 674.826014990668 -1.09689463999872 0.273512197987931 ENAH other 1 1 0.910506490844601 3.97437616834782 -1.09689463999872 0.336795246409782 16.6959707917905 24.6219995971167 0.678091587400791 0.498216204454235 97.8246423713353 66.5948315130293 1.46895247196768 0.142853208108899 PPP1R3A other 1 1 1 0.678091587400791 1.46895247196768 0.0218210235560284 49.0111127304953 17.7959436686241 2.75406090528969 0.00622262817043766 18.0010488896503 59.8865087395521 0.300586046315328 0.763925365725034 CCSAP other 1 1 1 2.75406090528969 0.300586046315328 0.000138813150200289 101.178641693272 35.8751088949126 2.8203020091075 0.00509818592891342 -107.02401199596 61.2392492600869 -1.7476375574335 0.0814889836352295 SH3RF1 other 1 1 1 2.8203020091075 -1.7476375574335 0.622805938854524 -181.62275382747 325.751641546886 -0.55754977308788 0.577541665610179 -655.619998286099 700.655752755223 -0.935723421534715 0.350121209827545 GBP5 other 1 1 1 -0.55754977308788 -0.935723421534715 7.84338775510924e-07 73.6450419720104 95.8210747335284 0.768568315235578 0.442716453738297 -862.885030762465 190.716400456566 -4.52444062858129 8.5460823848817e-06 BUB3 essential 0.00818379078368099 0.125969254353156 1 0.768568315235578 -4.52444062858129 0.0311476303169014 52.3787209310466 20.9447356670935 2.50080601462731 0.0128907100899254 -0.808027617693741 44.4425493473632 -0.0181813966471229 0.985505474260924 FAM69A other 1 1 1 2.50080601462731 -0.0181813966471229 3.69128198719656e-18 1332.63535316993 140.247502603154 9.502025550792 5.85943597375535e-19 15.5493126526182 527.367737783549 0.0294847627918418 0.976496943868966 ATP5G3 other 5.27041242131924e-14 1 8.65555882043141e-15 9.502025550792 0.0294847627918418 0.430524090969171 2.45498474059006 3.94267561721963 0.622669724556572 0.533945047133872 -8.92486236610617 9.46817988578512 -0.942616476848454 0.346588193780754 SRSF12 other 1 1 1 0.622669724556572 -0.942616476848454 0.934886857719263 93.8474602495607 271.160713305631 0.346095343626653 0.729500651517771 19.4844320260663 508.378812744928 0.0383266012225461 0.969451406664692 PDLIM3 other 1 1 1 0.346095343626653 0.0383266012225461 0.0554996243137732 -7.1026113548488 47.746580801863 -0.148756439425955 0.881840409416426 -200.650403093848 89.5164707481865 -2.24149144193012 0.0256859327831768 SORBS2 other 1 1 1 -0.148756439425955 -2.24149144193012 1.35341423352688e-09 140.393444286584 23.1547345040276 6.06327160702982 3.78968442507193e-09 -205.974013453565 107.106030825821 -1.92308511355935 0.0553649392640888 ELOC other 1.62707459154601e-05 1 4.96410762840173e-05 6.06327160702982 -1.92308511355935 0.737628891425504 3.61043653040066 5.38040714780695 0.671034074414288 0.502687462117905 -7.97933883922039 24.8551438697188 -0.32103370155671 0.748396397764606 LY96 other 1 1 1 0.671034074414288 -0.32103370155671 0.0112232124204495 64.6617398167434 142.266840265466 0.454510268844705 0.649851315585849 -664.383214165336 255.182368575992 -2.60356237726309 0.00977118924021589 CXADR other 1 1 1 0.454510268844705 -2.60356237726309 9.98622249048136e-06 30.9573843974487 66.8359587032332 0.463184564089318 0.643630260621098 -522.97318510202 119.882877950431 -4.36236762115653 1.87471850213068e-05 BTG3 other 0.095348452339116 0.274027603456441 1 0.463184564089318 -4.36236762115653 0.00980909536771674 82.147304816404 58.1434059328424 1.41283957309427 0.158927068749008 -208.585310150313 104.431150108006 -1.99734762984595 0.0468541532391698 C21orf91 other 1 1 1 1.41283957309427 -1.99734762984595 0.268714327583776 21.2783877859035 13.0940082240777 1.62504768759624 0.105392550553575 15.0258420422347 23.5180983367838 0.638905485769372 0.523460128418971 CHODL other 1 1 1 1.62504768759624 0.638905485769372 0.281352487506907 -0.838310094935141 13.0048989963853 -0.0644611000183967 0.948653782597653 -34.8971027213748 23.1976858695322 -1.50433551508725 0.133737407083051 NCAM2 other 1 1 1 -0.0644611000183967 -1.50433551508725 7.80964534423677e-06 45.4128941483151 9.30952231919 4.87811217281301 1.72028459367926e-06 -0.955184999694602 41.974183578003 -0.0227564878759232 0.98185925234312 L3MBTL4 other 0.0752849811184424 1 0.0202408685292302 4.87811217281301 -0.0227564878759232 0.0115559269861917 8.63033413210178 2.98076369877424 2.89534327583591 0.00404791089180136 -3.30877649288167 12.2579681711304 -0.269928624931038 0.787389153514785 PDE1C other 1 1 1 2.89534327583591 -0.269928624931038 5.74641767243766e-10 197.322898855563 30.8457404583351 6.39708743974218 5.97202097438344e-10 -77.5932636346272 116.715098855313 -0.664809132628304 0.506676575172074 RABGEF1 other 7.01350276921016e-06 1 7.99235567001736e-06 6.39708743974218 -0.664809132628304 1.01786106006873e-10 53.9376623376621 18.5615956623938 2.90587422109086 0.00398147538994317 -155.126569264069 32.6913147603678 -4.74519212216364 3.46006959531435e-06 MRPL39 essential 1.2722245389799e-06 0.0514512348823244 1 2.90587422109086 -4.74519212216364 0.193381010945139 0.688819875776388 14.0217038804656 0.049125261925979 0.960857627524368 41.5400038819876 24.6955026588406 1.68208780585873 0.0937664011635416 JAM2 other 1 1 1 0.049125261925979 1.68208780585873 1.1519242869238e-08 209.45652173913 73.6144049714278 2.84531976887441 0.00479416391154568 -512.66734601449 129.652198420304 -3.95417395355331 9.93526378314384e-05 ATP5J other 0.000133277639997083 1 1 2.84531976887441 -3.95417395355331 3.00235141057087e-08 54.2930547713155 25.3298152702175 2.14344456096972 0.0330163055541151 -193.784855543007 44.6117337583389 -4.34380911068681 2.01720886014471e-05 GABPA essential 0.000340616767529265 0.294552837758331 1 2.14344456096972 -4.34380911068681 0.451813542236737 211.172981894549 170.893814676152 1.23569704552928 0.217703910024595 78.3708454351698 293.41785967557 0.267096370758835 0.78961000192467 ADAMTS1 other 1 1 1 1.23569704552928 0.267096370758835 0.0587376484253968 40.4471757828498 19.6939975324131 2.05378190569388 0.041008602226944 66.2111578607687 33.794271804897 1.95924203495263 0.0511654957228664 ADAMTS5 other 1 1 1 2.05378190569388 1.95924203495263 3.55216857305589e-23 48.8716373616952 7.15201696542196 6.83326641952559 4.21933410206027e-11 -51.2570014581009 11.5112823453625 -4.4527620746572 1.1738407649181e-05 TSEN2 essential 5.2561438375508e-19 0.172448946774119 5.76993938456742e-07 6.83326641952559 -4.4527620746572 0.000381593153689235 -179.302546285015 55.3690155468222 -3.23831920279293 0.00132933310985727 -371.022844848595 134.751347071106 -2.75338876317736 0.00623726442619905 SLFN13 other 1 1 1 -3.23831920279293 -2.75338876317736 0.0599570657622263 85.0672544815165 37.6228860922618 2.26105074110763 0.0244294237669495 104.562682905908 60.5546192842238 1.72674990185514 0.0851806706050239 WNT7A other 1 1 1 2.26105074110763 1.72674990185514 1.59829425532737e-22 104.646636932843 38.365079501241 2.72765333196971 0.00673184431380904 -493.812664894071 61.7491910989906 -7.9970709916254 2.36987004791862e-14 XPC ts 2.3566848794802e-18 3.63680257553592e-10 1 2.72765333196971 -7.9970709916254 6.24769913713816e-38 96.4050450295916 10.3574192576303 9.30782491580326 2.17264149063573e-18 -101.275339222917 16.6704271005378 -6.075149641466 3.52507145807051e-09 CCDC174 essential 9.53086503370427e-34 5.369388844933e-05 3.2005181798555e-14 9.30782491580326 -6.075149641466 0.812525159241305 -11.5203820952406 30.4785522670368 -0.377983245211424 0.705695218230604 13.8607347772951 49.0773519050965 0.282426297248033 0.777800384953192 FGD5 other 1 1 1 -0.377983245211424 0.282426297248033 3.10665988084204e-27 248.025368023602 20.91203351894 11.8604136608219 3.84858209707098e-27 -75.7280003668771 44.589860441498 -1.69832333218967 0.0904188054371613 FLCN other 4.66527114306049e-23 1 5.82059556361015e-23 11.8604136608219 -1.69832333218967 1.80576461460598e-23 112.176014469024 17.7746434262456 6.31101349146545 9.29848026409571e-10 -146.080820910301 28.289185833947 -5.16383970071714 4.27480866489788e-07 DPH3 essential 2.67524027653876e-19 0.00643187711720535 1.23865055598019e-05 6.31101349146545 -5.16383970071714 3.11817362630652e-25 50.1794207409732 10.3856657937056 4.83160364850037 2.11008783588464e-06 -117.763406797367 16.6025668088953 -7.09308434972065 8.55228886717978e-12 OXNAD1 other 4.65325050253723e-21 1.30978304000858e-07 0.0247006882068656 4.83160364850037 -7.09308434972065 9.03393763888394e-22 126.868707839249 63.2162455214827 2.00690039075693 0.0456063555905525 -670.550588743833 97.217703289513 -6.89741236477211 2.86633166684934e-11 CXXC1 essential 1.32627238476455e-17 4.38806714877965e-07 1 2.00690039075693 -6.89741236477211 6.09324536643004e-12 76.2657701467596 24.4386034621716 3.12070901534169 0.00196961288835531 -126.149775350482 37.5831383309228 -3.35655245817214 0.000884906716990226 SKA1 essential 7.88283153055054e-08 1 1 3.12070901534169 -3.35655245817214 1.22139186973339e-41 1677.45174955228 108.473252778759 15.4641969940146 1.37588743837479e-40 -449.967660834825 454.913467480161 -0.98912802763846 0.323354886294615 PPP4R1 other 1.86677533370051e-37 1 2.10359430453122e-36 15.4641969940146 -0.98912802763846 0.00719542396607106 257.319560938766 82.0010265929239 3.1380041400722 0.00186188071266924 70.3196201180166 343.494884741428 0.204718099866177 0.837924592083254 APCDD1 other 1 1 1 3.1380041400722 0.204718099866177 0.0690817375694216 -15.3807956920455 8.56902262524349 -1.79492998965077 0.0736295555405978 -65.4978350900606 36.392161870913 -1.79977862602361 0.0728584940524948 PIEZO2 other 1 1 1 -1.79492998965077 -1.79977862602361 0.0140118307087053 3.17682627235809 2.88616329708123 1.10070912327477 0.271850561440571 -14.3698363327321 5.39663947758049 -2.66273787464021 0.00814260837195193 CCDC144B other 1 1 1 1.10070912327477 -2.66273787464021 2.03418979800778e-20 155.841109298638 15.1939895342311 10.2567603424722 1.83607029321258e-21 115.927540385984 64.9589627028554 1.78462733335624 0.0752933228716179 MPPE1 other 2.96015299406093e-16 1 2.74272180400095e-17 10.2567603424722 1.78462733335624 3.14811501408002e-06 62.793706699614 16.0592336678943 3.91013095632025 0.00011271960592644 -92.8978165677631 29.8352972597728 -3.11368831886981 0.00201510357504033 USP43 other 0.0313615217702652 1 1 3.91013095632025 -3.11368831886981 0.19894958342997 85.6187775529842 47.9075660909325 1.78716608959998 0.0748570061637234 -0.910880042202155 196.105723114945 -0.00464484170953162 0.996296860083996 RAB6B other 1 1 1 1.78716608959998 -0.00464484170953162 0.00128694819699578 57.8427506528997 17.601226857972 3.28629084322615 0.00112823000695792 -61.3712409992105 41.9826897244688 -1.46182251308785 0.144774235847596 EME1 other 1 1 1 3.28629084322615 -1.46182251308785 0.167764298209599 24.2167475303169 14.6550967761962 1.65244541882872 0.0994276479466052 -45.0750045656427 62.3283313637064 -0.723186447951175 0.470095259034455 EPHB1 other 1 1 1 1.65244541882872 -0.723186447951175 0.00462548951387299 164.994683379888 63.3681672411173 2.60374712672498 0.00965917654124259 -343.434485519902 276.273074584705 -1.24309792416852 0.214759149353702 ACSS1 other 1 1 1 2.60374712672498 -1.24309792416852 1.15018393907619e-09 236.650697560596 35.8115704038082 6.60821893293543 1.63222592846432e-10 -7.84372240572966 86.3837860696745 -0.0908008639422583 0.927707811533117 ANKRD40 other 1.38597164658681e-05 1 2.20840168121222e-06 6.60821893293543 -0.0908008639422583 2.79738390752729e-09 47.8194394798794 7.6718367553234 6.23311483351077 1.44657297938635e-09 -20.335292090478 14.1663193359369 -1.43546757688088 0.152133676900407 ZNF18 other 3.32664894283145e-05 1 1.91613056849515e-05 6.23311483351077 -1.43546757688088 2.19626828147487e-44 595.248441077274 34.9169829566133 17.0475336261701 1.70166365879601e-45 310.286979600626 297.914914354871 1.0415288548831 0.298506733811172 VOPP1 other 3.36094935114099e-40 1 2.60575756071433e-41 17.0475336261701 1.0415288548831 0.287356850847323 1.66865228546864 4.29849455866088 0.388194578984992 0.698131788886747 12.2493415209515 7.80984665649435 1.56844840362717 0.117771009747406 DKK2 other 1 1 1 0.388194578984992 1.56844840362717 0.209285857098285 10.8220962102559 7.99826548275777 1.35305538851962 0.176999063298239 -8.35962357984052 14.5182420441999 -0.575801364544699 0.565156699920935 CYP2U1 other 1 1 1 1.35305538851962 -0.575801364544699 6.62278496673052e-07 34.5993772763917 6.55125795872012 5.28133337053808 2.37843050866905e-07 -16.9196908532272 31.4379821701393 -0.538192647405278 0.59081935996242 RSPH10B other 0.00693869180964356 1 0.00291666933278085 5.28133337053808 -0.538192647405278 2.56929826651347e-15 77.2741338043254 9.27475216835172 8.33166562315361 2.39452469587296e-15 -44.8525565473761 44.5074053164082 -1.00775491692931 0.314335919582686 FBXL18 other 3.54948555518836e-11 1 3.45913037565808e-11 8.33166562315361 -1.00775491692931 0.330679452822807 -419.169886976187 304.95420732617 -1.37453387067998 0.170295074389636 410.413928705563 1043.77868513657 0.393200143430659 0.694449087626762 PROM2 other 1 1 1 -1.37453387067998 0.393200143430659 0.0253449664794615 -8.57175477815801 5.79206637801209 -1.47991307742919 0.139880248790519 -33.9765570327668 13.087610086711 -2.59608567245339 0.00986411337758939 AK9 other 1 1 1 -1.47991307742919 -2.59608567245339 1.92227158521532e-15 725.718205810153 83.7558885962528 8.66468278198915 2.33515925123409e-16 -160.451299244454 478.536179577299 -0.335296067658215 0.737622841039114 KLF10 other 2.66157723688913e-11 1 3.39812374239585e-12 8.66468278198915 -0.335296067658215 0.421758481996316 -12.2934139245826 15.4802424897106 -0.794135746436391 0.427710490205753 -45.3342632630458 34.8231245052147 -1.30184364290048 0.193915044536796 PTPRN2 other 1 1 1 -0.794135746436391 -1.30184364290048 5.46628895146625e-09 532.96154388506 84.3482120700778 6.31858732752115 8.9025758057058e-10 434.104404926852 481.965281976014 0.900696421839895 0.368431356587175 AZIN1 other 6.42452940465829e-05 1 1.18644627762641e-05 6.31858732752115 0.900696421839895 8.25208199641879e-19 265.832129428558 27.2530441854091 9.75421782682466 7.77093547559864e-20 83.8243515062305 155.723764655648 0.538288755679593 0.590754274887478 ATP6V1C1 essential 1.18549409960552e-14 1 1.1527405684503e-15 9.75421782682466 0.538288755679593 7.28610915891994e-12 66.8578967419614 9.11273217219935 7.33675647199728 1.81418899752888e-12 -29.5761297352941 46.1091169795613 -0.6414377822157 0.521697449956046 OTUD6B other 9.40490970233386e-08 1 2.53823182644265e-08 7.33675647199728 -0.6414377822157 0.00925741811331906 6.75892306879622 27.4105984696335 0.246580645668281 0.805390888420884 -182.010736995403 62.274687141555 -2.92270817164731 0.00371715483406542 CDK19 other 1 1 1 0.246580645668281 -2.92270817164731 3.27015566415081e-05 125.193498969907 34.5669602941795 3.6217676620813 0.000340108168198471 -149.939345539769 78.5333687675358 -1.9092437761533 0.0571248254632605 GTF3C6 essential 0.297486060767799 1 1 3.6217676620813 -1.9092437761533 1.35987660882e-20 220.764029552594 22.5547524118991 9.78791633448065 6.21697986092611e-20 -151.713353473393 84.2949214639513 -1.79979233432554 0.0728471796736481 TTC39B other 1.98188416969427e-16 1 9.22910660354481e-16 9.78791633448065 -1.79979233432554 3.66896023216541e-22 184.52208353326 36.3972759683726 5.06966740295619 6.76778012870529e-07 -283.389657841215 70.0571386513971 -4.04512178625159 6.56496270475681e-05 AGPAT5 other 5.39924187765461e-18 0.943056892538316 0.00812810393457505 5.06966740295619 -4.04512178625159 9.87796293206231e-20 299.050013642458 48.5546733681615 6.15903666728304 2.19417849624369e-09 -371.864088046293 88.9269689304208 -4.18167955704474 3.74009330035207e-05 MMS19 essential 1.43121804922651e-15 0.541939519221016 2.89346318299656e-05 6.15903666728304 -4.18167955704474 9.19416575056153e-12 265.765430664329 66.7737231105631 3.98009004566479 8.52810668229386e-05 -454.818630157971 122.294815071606 -3.71903444877581 0.000236086734795064 PI4K2A other 1.18319719043976e-07 1 0.890846024032417 3.98009004566479 -3.71903444877581 2.04618888470308e-05 422.405120947897 132.185155632661 3.19555640666453 0.00153478410407393 -390.649611200829 242.094620612079 -1.61362367413685 0.107594723041479 MARVELD1 other 0.189804480945057 1 1 3.19555640666453 -1.61362367413685 1.05741620388884e-05 -3.54424399242333 25.8002621154822 -0.137372402518985 0.890822836803364 -207.201665119652 47.2526936829247 -4.38497044232056 1.57590104124541e-05 ZFYVE27 other 0.100676596772257 0.230822225511215 1 -0.137372402518985 -4.38497044232056 0.00468098676933768 136.958597424774 85.5318432235107 1.60125857532235 0.1103063499573 -285.621534282606 156.649958433996 -1.82331062923934 0.069189169828212 GOLGA7B other 1 1 1 1.60125857532235 -1.82331062923934 0.182607553981709 54.2640923724948 35.5029133698047 1.5284405481677 0.127391037779032 1.17971422670916 65.8407720190968 0.0179176852052553 0.985715686876979 GPR78 other 1 1 1 1.5284405481677 0.0179176852052553 2.27653929138855e-08 36.1025597281541 11.3948627291349 3.16831896849845 0.00168121302504581 -52.2263274779939 21.1319716588656 -2.47143656640686 0.0139773227447585 TRMT44 other 0.00025991249089783 1 1 3.16831896849845 -2.47143656640686 0.000133115553384747 -71.0756492510791 61.971657011529 -1.14690574173055 0.252277391085065 -475.207326465608 113.342431311604 -4.19266924986951 3.57238597889685e-05 SLC25A28 other 1 0.518067414659621 1 -1.14690574173055 -4.19266924986951 0.00139841682036225 49.729850891726 38.5489284331294 1.2900449613792 0.198212925513061 -191.39460091609 70.3777874349735 -2.71953137334605 0.00699032013034917 HSPA13 other 1 1 1 1.2900449613792 -2.71953137334605 0.0123779466776184 -39.469831833588 16.1412032865078 -2.44528435290696 0.0151563204426984 -73.7179991120639 29.4685798027597 -2.50157963517334 0.0129965473985933 SAMSN1 other 1 1 1 -2.44528435290696 -2.50157963517334 0.0158570371267387 51.9109891069437 35.8961411400447 1.44614399927889 0.14937939118174 -118.328835187652 65.4508832771967 -1.8079028007385 0.0718138475969768 USP25 other 1 1 1 1.44614399927889 -1.8079028007385 1.59726980321976e-06 37.2908018704752 13.0747170967134 2.85213068815455 0.00462698888242998 -59.9967889366862 19.5436829456255 -3.06988140892428 0.00232598486884914 ZCCHC10 other 0.0162745820250061 1 1 2.85213068815455 -3.06988140892428 3.17346285535207e-15 48.102277105631 7.48165381838424 6.42936418515276 4.91557291970574e-10 -45.498660354809 20.2265809154948 -2.24944890809273 0.0251946526911508 C16orf87 other 4.37525323867391e-11 1 6.59129172803342e-06 6.42936418515276 -2.24944890809273 2.59253903786939e-07 46.310043929529 84.4022106813253 0.548682831358296 0.583606936461947 -732.573260511809 154.369663532807 -4.74557787940065 3.14300219032309e-06 MOV10 other 0.00279657186014971 0.046752157581056 1 0.548682831358296 -4.74557787940065 9.06131364978998e-06 187.521172743433 279.005267869065 0.672106208515873 0.502002569899941 -2051.28643632414 510.294090369812 -4.01981225147554 7.27341819262143e-05 RHOC other 0.0868436300195872 1 1 0.672106208515873 -4.01981225147554 0.00345617292504662 9.09372563318652 7.45413529781449 1.2199571472566 0.223382256198014 -30.6326157686591 13.6219868757264 -2.24876268404314 0.0252097192715575 PPM1J other 1 1 1 1.2199571472566 -2.24876268404314 0.0731690929861122 58.5917733445028 188.314483921477 0.31113790147408 0.755901588612551 1374.0725257263 598.397960750404 2.29625201931367 0.0223176757859182 DBI other 1 1 1 0.31113790147408 2.29625201931367 3.95393548974823e-07 1060.94081763698 273.930696660943 3.87302639159917 0.000130436756392223 -861.445049813202 499.476801623543 -1.72469481468025 0.0855511143448632 SLC16A1 other 0.00421054590303289 1 1 3.87302639159917 -1.72469481468025 1.19801277492515e-14 81.1804161053881 16.0228751918344 5.06653238781761 6.93810396314133e-07 -153.967575227975 42.4564096529504 -3.62648600026581 0.000335300695519225 HEATR3 other 1.63768346332268e-10 1 0.00832641856616591 5.06653238781761 -3.62648600026581 0.1626657793642 4.97190036080363 4.36450251705743 1.13916771530601 0.255498754373253 -17.7816105630426 15.0116359883842 -1.18452183205094 0.237099524217804 TRIM74 other 1 1 1 1.13916771530601 -1.18452183205094 1.2225256641938e-07 209.205132618221 37.1445064942379 5.63219577707069 3.94445969687684e-08 -45.3828298709636 115.988384902524 -0.391270469962169 0.695861851812401 NIFK other 0.00134208867415195 1 0.000498816373267045 5.63219577707069 -0.391270469962169 2.14134647517818e-16 429.702521750142 55.983271008133 7.67555225002334 2.01195479901576e-13 -442.236231016641 153.446267724824 -2.88202663755697 0.0042183876260724 OXA1L other 2.99938400778207e-12 1 2.84973277732593e-09 7.67555225002334 -2.88202663755697 0.567508059756676 -11.1600847826464 17.7898623453625 -0.627328338240667 0.530891383686377 -47.7071855028619 48.7607803380707 -0.978392576412765 0.328619277251094 SLC7A7 other 1 1 1 -0.627328338240667 -0.978392576412765 3.69759067294832e-11 1099.2271250127 220.330236610861 4.98899806908532 9.97806456619848e-07 -1036.236367475 321.677570907313 -3.22135100856495 0.00140707837947729 LARP1 other 4.68965425050035e-07 1 0.0118988419951917 4.98899806908532 -3.22135100856495 6.10699719167885e-09 111.679630167011 42.2008020376526 2.64638643756978 0.00853787319648321 -279.379115990034 61.401150482615 -4.5500632120751 7.6246395139362e-06 CNOT8 other 7.16045420724346e-05 0.112532054586184 1 2.64638643756978 -4.5500632120751 9.58666504632725e-05 17.074085266715 5.4096380701256 3.1562343072461 0.00175120889605225 -13.9072096216651 9.07811274465931 -1.53194942746737 0.12652911147848 SETD9 other 0.827712660099895 1 1 3.1562343072461 -1.53194942746737 3.8725469070281e-06 56.7735647718099 17.0077074621887 3.33810802531899 0.000943633251556349 -63.2174855434788 28.2615911685401 -2.23686929608728 0.025987684114885 MIER3 other 0.0383033614574149 1 1 3.33810802531899 -2.23686929608728 1.88896296054941e-16 445.917225550017 87.5772742665764 5.09170020743841 6.08904480147593e-07 -813.235648360673 192.559933981281 -4.22328587025653 3.14724800084626e-05 NUP205 essential 2.64757048550605e-12 0.457074827162903 0.00733242774993732 5.09170020743841 -4.22328587025653 0.000694428128229665 26.2258613960513 6.82295159288796 3.84377069645172 0.000146316738545955 21.7892984108402 23.9269130349098 0.910660659778769 0.363163953750221 ZKSCAN2 other 1 1 1 3.84377069645172 0.910660659778769 1.93767574403912e-20 57.503340143053 7.09468316001038 8.10513152541809 1.12806493642081e-14 -62.4590473189642 13.6606332297369 -4.57219268452369 6.90631490023589e-06 C9orf85 other 2.82009327787454e-16 0.102096053170187 1.62035247467485e-10 8.10513152541809 -4.57219268452369 0.829321227597059 -41.4407741083122 67.7585896258985 -0.611594402084083 0.541240390040769 -37.4210863225985 124.098579527929 -0.301543228495832 0.763196152661235 PIK3AP1 other 1 1 1 -0.611594402084083 -0.301543228495832 0.109001398625725 6.94231486587549 3.32819593872816 2.0859093015204 0.0377989378597079 7.13060456531682 12.4863037081515 0.571074093020955 0.568360525444598 RBM45 other 1 1 1 2.0859093015204 0.571074093020955 0.254999844086952 2317.452634208 1589.5279267442 1.45795024750197 0.145900294373521 -3659.35403270456 5992.18734957955 -0.610687520135919 0.541868846517826 TTN other 1 1 1 1.45795024750197 -0.610687520135919 1.50020247662675e-12 1648.99500493435 277.897633573547 5.93382168725067 7.75204354722068e-09 -744.49291296056 622.078438145719 -1.19678302173554 0.23228539978219 PDIA4 other 1.9694658113156e-08 1 0.000100520748676811 5.93382168725067 -1.19678302173554 0.0339453848343933 -4.98446288025694 3.56606360388217 -1.39774929275817 0.163159580536218 -31.9408868859077 12.6499657133784 -2.52497813904171 0.0120549438718876 KDM8 other 1 1 1 -1.39774929275817 -2.52497813904171 1.0430444130287e-15 81.8218935482953 10.961064826347 7.46477599070672 8.17198902729114e-13 -63.9470947454872 27.0608921356597 -2.36308154309593 0.0187289376168893 KCTD18 other 1.44889299413816e-11 1 1.14800101855386e-08 7.46477599070672 -2.36308154309593 1.04853470068821e-08 84.0237282763759 18.512273280394 4.53881200886138 8.05087396070416e-06 -130.380386210774 45.7034638844985 -2.85274627192965 0.00462008789122789 FAM126B other 0.000121525171809763 1 0.0909829266299177 4.53881200886138 -2.85274627192965 4.86750547924401e-17 211.640608599819 33.2387265892675 6.36728991501605 6.74828124062855e-10 -348.702551498254 80.9131362778264 -4.30959134127412 2.18532544234161e-05 TMEM237 other 6.86318272573406e-13 0.318751569019947 9.02177719059631e-06 6.36728991501605 -4.30959134127412 7.30373862694946e-05 454.262387099845 102.726135058229 4.42207221017664 1.34244627952873e-05 280.818090057794 249.937440023202 1.12355351815929 0.262047304977767 FZD7 other 0.639223204630617 1 0.14932029967198 4.42207221017664 1.12355351815929 0.0185291271660259 -43.738880573453 19.1585027250566 -2.2830009840095 0.0230983308074076 -89.0916450878404 35.2644222600181 -2.52638890355082 0.0120153644351737 SPAG17 other 1 1 1 -2.2830009840095 -2.52638890355082 0.949296687968596 5.91289981195536 21.4575781636802 0.275562310287362 0.783062673661322 -17.9609206701452 118.594851730599 -0.151447726507937 0.879718272976825 DEPTOR other 1 1 1 0.275562310287362 -0.151447726507937 9.82671900705179e-08 158.008298328449 34.8144510281634 4.53858365311081 8.02501085829722e-06 -203.317228915663 66.624736941477 -3.05167777389135 0.00246620069524433 RNF20 essential 0.00108496804556859 1 0.0907066977313335 4.53858365311081 -3.05167777389135 0.0382001153135354 17.6652795651075 29.1329657140995 0.606367361924916 0.544700745254857 -90.7381920519739 42.0686231255597 -2.15690900510704 0.0317571265206717 PPARGC1B other 1 1 1 0.606367361924916 -2.15690900510704 0.430008007354965 8.88699268084447 19.269579914728 0.461192860465631 0.644974535842645 -88.0016307155863 78.5666576559571 -1.12008876718346 0.263518527634097 ELMO1 other 1 1 1 0.461192860465631 -1.12008876718346 0.96793504334129 21.9885804659219 89.6117281290038 0.245376145790509 0.806322487645512 1.83666824474067 129.401244462547 0.0141935902731775 0.988684378651071 SLC26A2 other 1 1 1 0.245376145790509 0.0141935902731775 3.52000253254076e-10 39.2592837496242 8.22606233647353 4.77254877774904 2.77095670219965e-06 -35.5234833861764 11.7951232639884 -3.01170938116711 0.00280479786595608 LSM11 essential 4.33030711553165e-06 1 0.0322289974032841 4.77254877774904 -3.01170938116711 3.83086478061423e-09 24.15385351907 7.5934786119735 3.18086805182856 0.00161221468978003 -46.4100463093592 11.0483284778404 -4.20063961733611 3.45526950851472e-05 MED7 essential 4.53152994898857e-05 0.50125594760023 1 3.18086805182856 -4.20063961733611 7.28159552666627e-84 677.56697890354 25.0522236743649 27.0461811179209 1.89737876779105e-84 46.3602283695898 94.3992155097309 0.491108195330404 0.62368867919741 RRAGA other 1.11852588885121e-79 1 2.91456352520383e-80 27.0461811179209 0.491108195330404 7.14657976455068e-05 2.99135964684318 2.19834155596216 1.36073470418201 0.174570323192452 30.4177815012859 6.90731970881378 4.4037025624386 1.45977873347359e-05 SLC24A2 other 0.62618331896993 0.214061953476567 1 1.36073470418201 4.4037025624386 0.0110172569024097 90.1891260555514 29.8380063327874 3.022625742808 0.00270896433506648 34.2242379471134 149.170175799797 0.229430834706839 0.818681104853332 PXYLP1 other 1 1 1 3.022625742808 0.229430834706839 3.71712771971063e-09 64.3312934818297 11.1378859161008 5.77589804442451 1.81776330007708e-08 -121.385439696227 55.6820178135415 -2.17997559109121 0.0299900275165757 RASA2 other 4.3995923690495e-05 1 0.000233109965601885 5.77589804442451 -2.17997559109121 0.0048473092192792 16.3979730981521 13.0734205435579 1.25429860100634 0.21064891621844 -76.6815173723716 28.8106070300602 -2.66157243033319 0.00817022635910648 RMND1 other 1 1 1 1.25429860100634 -2.66157243033319 0.00252586039973678 -7.49063877338777 35.8683615248523 -0.208836937483127 0.834708406236719 -270.217248347825 78.618123131882 -3.43708597436923 0.000665695585323703 RAET1L other 1 1 1 -0.208836937483127 -3.43708597436923 0.197711396463173 -25.2114894812262 15.7351893203845 -1.60223617065512 0.11009310215017 -88.1663804293835 89.1012754337702 -0.989507501437713 0.323164846052626 SLA other 1 1 1 -1.60223617065512 -0.989507501437713 6.26555067102783e-09 123.379601233841 19.5171994404482 6.32158325841278 8.84489199272575e-10 29.0579691976367 89.561466618776 0.324447223729864 0.745814817050438 TMBIM4 other 7.34197227631041e-05 1 1.17902410263034e-05 6.32158325841278 0.324447223729864 0.00138989019858893 -3.30436148489448 2.89282229361643 -1.14226217496532 0.254201685898795 -18.4239663507688 5.37737826947536 -3.4261986840971 0.000692225625356574 MICU3 other 1 1 1 -1.14226217496532 -3.4261986840971 9.17191858211595e-06 27.4868767474635 6.08861840204104 4.51446862530412 8.97947195744727e-06 -58.0780771595289 39.1267979404308 -1.48435548566869 0.138714585686574 GRIP1 other 0.0878302923423423 1 0.101198648960431 4.51446862530412 -1.48435548566869 1.08269625112228e-29 118.214829079394 23.324257771394 5.06832115465551 6.80151301440991e-07 -259.813203049046 43.3715472312626 -5.99040660605647 5.62836728059151e-09 VPS37A essential 1.63541268732021e-25 8.56524932760415e-05 0.00816589652510053 5.06832115465551 -5.99040660605647 0.959825002475369 1.12186476759661 3.91838163124383 0.286308193834732 0.774827350203114 0.604169323691706 12.8383721413784 0.0470596518809775 0.962495040224695 KIF5A other 1 1 1 0.286308193834732 0.0470596518809775 4.27497440357188e-10 120.301821186185 61.3795473332739 1.95996592371364 0.0508728080493383 -436.76123275592 114.283778425917 -3.82172552195626 0.00015940307164548 PSD3 other 5.24368360342127e-06 1 1 1.95996592371364 -3.82172552195626 1.12989982736847e-13 124.14071796535 16.646688441062 7.45738219375422 8.35502317131626e-13 -52.6085928827127 32.0527781374122 -1.64131148498818 0.101715197924039 CARNMT1 other 1.51666453827670e-09 1 1.1736301048748e-08 7.45738219375422 -1.64131148498818 4.50754914530329e-07 126.478885420182 36.7319090364389 3.44329736019742 0.000651128477541771 -235.038189757003 85.2711456277142 -2.7563625189599 0.00618003061258138 MCU other 0.00477980511367961 1 1 3.44329736019742 -2.7563625189599 1.24042247718766e-08 263.058199843718 47.050161415886 5.59101588448321 4.84177355553059e-08 -193.1216383628 145.960798562309 -1.32310620567315 0.186744690895392 ELMSAN1 other 0.000143268796115174 1 0.000610402392145741 5.59101588448321 -1.32310620567315 0.292960162806419 4.44784895685159 4.21094942644751 1.0562579851746 0.291647134030228 -6.83600121965376 9.92948376592954 -0.688454846274057 0.491665186316077 CFAP70 other 1 1 1 1.0562579851746 -0.688454846274057 0.310009615164011 -3.25026448319738 3.70755700095887 -0.876659342622859 0.381329326057242 7.62382932667697 7.13701885881738 1.06820921696994 0.286231311166747 GNA14 other 1 1 1 -0.876659342622859 1.06820921696994 1.02736104274947e-12 116.282423975992 16.1686125562626 7.19186161282292 4.57768409081266e-12 -57.5032024296267 49.8272406623614 -1.15405151208912 0.249342910395322 FAM161B other 1.35313722940532e-08 1 6.36526972827501e-08 7.19186161282292 -1.15405151208912 1.85385679171016e-10 263.499739173253 43.6499021317951 6.03666277137689 4.35516723529807e-09 -185.275732061863 84.0257276205289 -2.20498813052346 0.0281659238034029 GNAQ other 2.30156320690817e-06 1 5.69220357653458e-05 6.03666277137689 -2.20498813052346 0.943408444092601 -25.3037257094707 79.7239973231439 -0.317391582949706 0.751157437080658 -52.6617225972266 322.182447829849 -0.163453108485408 0.870266842169295 WIF1 other 1 1 1 -0.317391582949706 -0.163453108485408 0.0269380386469147 14.8794698493774 6.06611142696268 2.45288436068633 0.0147048818587701 41.7708547186207 30.7171388971203 1.35985499360869 0.17483312992992 MMP16 other 1 1 1 2.45288436068633 1.35985499360869 2.92010131579619e-08 157.043769642225 54.8383608759952 2.86375754368998 0.00446379460018496 -494.30772267811 129.250238993248 -3.824424051579 0.000157654778452647 ADK other 0.000331460700356025 1 1 2.86375754368998 -3.824424051579 0.222138438672737 56.7140884936105 43.2089766042096 1.31255338475397 0.190277037275594 -56.069772692586 101.780016042746 -0.550891765128405 0.582093474489244 KCNMA1 other 1 1 1 1.31255338475397 -0.550891765128405 0.000755192878021614 -30.8672738411273 8.58689953498858 -3.59469372098207 0.00037612946264113 13.3172821552553 27.8212654094832 0.478672769165846 0.63249935752896 BATF other 1 1 1 -3.59469372098207 0.478672769165846 0.000366182853779796 107.424597147917 30.3581909424936 3.53857044220478 0.000461881135479369 -40.4454128802684 67.7102017321369 -0.597331153143973 0.550708736445264 DCK other 1 1 1 3.53857044220478 -0.597331153143973 0.0641943626178822 7.31010028791719 3.91854285469032 1.86551495262259 0.0630299307852024 -5.93427180151104 8.49027950575307 -0.698948933010973 0.485094819648261 ADAMTS3 other 1 1 1 1.86551495262259 -0.698948933010973 0.00585075199385739 15.0419228764981 10.8295802328346 1.38896638217721 0.165808838683651 -40.6164929650859 20.0929790650637 -2.02142712803136 0.0440676891844654 ALX3 other 1 1 1 1.38896638217721 -2.02142712803136 5.59215805294413e-05 95.3566421277301 21.3867656691232 4.4586752201339 1.14265392360464e-05 102.156464476055 108.397063939047 0.942428334899353 0.346684321638376 DPY19L4 other 0.496136262457204 1 0.127623016727402 4.4586752201339 0.942428334899353 6.22565423186835e-06 32.7741244766762 7.171641234173 4.56996152017573 6.97568080809203e-06 -58.2392203957997 36.3488741325152 -1.60222900394329 0.110091595348141 NDUFAF6 other 0.0605133591337603 1 0.0791879285334607 4.56996152017573 -1.60222900394329 0.0161478815288408 -12.9516919285984 34.7126722901814 -0.37311134735835 0.709312605530861 -175.938375691241 64.2498852234822 -2.7383453694784 0.00652065483032039 DRAM2 other 1 1 1 -0.37311134735835 -2.7383453694784 3.63358126293744e-05 11.9798220196786 2.76020008348709 4.3402005859459 1.91170342775283e-05 -15.8048990233722 13.9898472524191 -1.12974064249624 0.259431644977635 C8orf37 other 0.328948111733727 1 0.210402079258476 4.3402005859459 -1.12974064249624 0.651357932603724 0.468575466064777 13.8396675229497 0.033857422173456 0.973012289546424 24.0663065397764 27.2983662451388 0.88160244915983 0.378664029846104 ADAMTSL3 other 1 1 1 0.033857422173456 0.88160244915983 0.275544741904405 7.42033196248578 10.7629610193821 0.689432206353174 0.491055665649709 -24.6173327887078 22.0690566942091 -1.1154682834798 0.265494691890416 ART3 other 1 1 1 0.689432206353174 -1.1154682834798 3.18108740476271e-05 38.8270946847715 14.486986724545 2.68013600226385 0.00774629715325616 -75.0399980333642 28.5751856928138 -2.62605460696045 0.0090600078285938 WHAMM other 0.289765251699835 1 1 2.68013600226385 -2.62605460696045 0.446355109296339 -92.7935216775662 74.7873982070135 -1.24076413810668 0.215610364444793 -104.820017193716 140.449573325992 -0.74631780440103 0.456028564725406 CXCL13 other 1 1 1 -1.24076413810668 -0.74631780440103 6.42149344163872e-08 10.4535385856469 6.06496329234792 1.72359469987824 0.0857977609530873 -46.9400044493511 9.8785656413144 -4.75170243876675 3.11570804017864e-06 N6AMT1 other 0.000715611229136219 0.0463492728056975 1 1.72359469987824 -4.75170243876675 3.90874002824467e-10 59.8645671550559 17.5174642627236 3.4174219657148 0.000718313779013764 -126.003425584601 28.5323112848888 -4.41616609066419 1.39820495554544e-05 RWDD2B other 4.80188712469858e-06 0.205144631077627 1 3.4174219657148 -4.41616609066419 4.16804758688373e-06 34.3884574681525 34.4488881929197 0.99824578591829 0.318954095192326 -244.491348922696 56.1100845760134 -4.35735128132767 1.80276706385503e-05 USP16 other 0.0411042249101324 0.263672710759437 1 0.99824578591829 -4.35735128132767 2.38888374105008e-14 361.812784191913 125.271688031648 2.88822470485515 0.00415238000102303 -1307.3036806946 204.041563578833 -6.4070459849692 5.63840696759081e-10 CCT8 essential 3.2484041110799e-10 8.61379432438848e-06 1 2.88822470485515 -6.4070459849692 0.280992687303334 26.1333562414093 17.7085929512481 1.47574436395679 0.14104413183954 31.2037644974042 29.1342463425816 1.07103386614116 0.285000990651461 MAP3K7CL other 1 1 1 1.47574436395679 1.07103386614116 0.507413250839311 -6.06742816415339 27.0084795162585 -0.224649009230635 0.822400336180969 44.3305949433568 44.3458207581286 0.999656657278826 0.31825634738867 CLDN17 other 1 1 1 -0.224649009230635 0.999656657278826 0.633707203324131 21.6869162165204 24.6737844651204 0.878945678040498 0.380111504597766 26.4229827819042 40.5124332399481 0.652219100872206 0.514743143584427 CLDN8 other 1 1 1 0.878945678040498 0.652219100872206 0.00139179376748199 231.90232624479 91.5188460994243 2.5339297437476 0.0117713611158049 -246.402183615065 151.797694428986 -1.62322744454025 0.105557209266367 TIAM1 other 1 1 1 2.5339297437476 -1.62322744454025 7.26588990204065e-09 156.086043234163 41.0069092368305 3.80633522835643 0.000169762553190172 -232.407878809099 67.6718702385015 -3.43433509359214 0.000674329282843385 SCAF4 other 8.48801258356389e-05 1 1 3.80633522835643 -3.43433509359214 0.470148877575939 8.3496304967765 8.1550393061455 1.02386146569329 0.306676500995641 -7.94611022958028 15.5962582771341 -0.509488243166003 0.610762301681307 CDK20 other 1 1 1 1.02386146569329 -0.509488243166003 0.0140441904214209 -1.44803122034868 9.71569587172576 -0.149040402197302 0.881615928101126 -48.4701225365424 17.8819974967917 -2.71055415063327 0.00708055992230749 PCGF6 other 1 1 1 -0.149040402197302 -2.71055415063327 0.0849760143878864 24.9073442092598 36.4408562214169 0.683500520896687 0.494793064484381 -196.733367655443 107.992625389938 -1.82172965001158 0.0694442790741123 ANKRD9 other 1 1 1 0.683500520896687 -1.82172965001158 0.00466058602853515 37.5462422504954 16.0853966589611 2.33418193200592 0.0202047211775542 -32.3816004204989 29.64176943471 -1.09243142491287 0.275465270032176 SFR1 other 1 1 1 2.33418193200592 -1.09243142491287 0.0484039174397296 -3.05844942514805 15.7239212157483 -0.194509332830086 0.845900515087325 -66.7300971016576 28.9361161254911 -2.30611796041529 0.021742830145307 SFXN2 other 1 1 1 -0.194509332830086 -2.30611796041529 0.0012334771445094 149.935249635336 64.2811979580337 2.33248997215674 0.020304561675569 -382.561358823602 189.760543155671 -2.01602162631757 0.0446463612517229 C14orf2 other 1 1 1 2.33248997215674 -2.01602162631757 0.140658493050058 -2.86216817762353 61.7154238363068 -0.0463768698277938 0.963038982315067 -201.802161180778 111.9064100984 -1.80331190146598 0.0722856788450883 FUT6 other 1 1 1 -0.0463768698277938 -1.80331190146598 0.351943383741044 -28.7746439189942 20.3474636714801 -1.41416367089162 0.158314142212976 -43.2038300037016 60.4226348211377 -0.715027243210976 0.475128615402905 TDRD9 other 1 1 1 -1.41416367089162 -0.715027243210976 0.0281816410505517 134.502022829404 106.918892717795 1.25798181603332 0.209318366378805 -276.50726536734 152.450601963723 -1.81374990853193 0.070655734472475 PCDH1 other 1 1 1 1.25798181603332 -1.81374990853193 3.44687776654728e-06 233.714943022208 94.2852849863153 2.47880613667477 0.0136972888522237 -458.228216656079 137.169109158606 -3.34060795077585 0.000934823354298341 SH3RF2 other 0.0342171555885148 1 1 2.47880613667477 -3.34060795077585 0.916740000172276 0.135017458532039 2.29083116622945 0.0589381969838783 0.953038122268542 4.86506958607358 11.6829224054212 0.416425738119777 0.677377665871972 GDF6 other 1 1 1 0.0589381969838783 0.416425738119777 5.21693773401756e-05 342.683879248837 81.4783032909859 4.20582983944818 3.38098391693298e-05 -520.332582554818 415.528088279299 -1.25221999963833 0.211404145568365 UQCRB essential 0.464620474591604 1 0.36575484013381 4.20582983944818 -1.25221999963833 1.12528655278252e-10 83.4634200965063 11.9399337568283 6.99027497106291 1.603033507876e-11 -0.223922866075975 61.2285958693949 -0.00365716154186549 0.997084292577056 MTERF3 other 1.40390750325147e-06 1 2.20914047720392e-07 6.99027497106291 -0.00365716154186549 9.74215126864942e-08 511.309899960025 91.0078304503214 5.61830666031682 4.19474462034899e-08 954.445559767009 466.692846466288 2.04512575453833 0.0416600879627403 PTDSS1 other 0.00107638775361986 1 0.000529922087888688 5.61830666031682 2.04512575453833 0.6584805746733 1.73088927578123 20.5309951447131 0.0843061558186062 0.932865735193157 -24.6528780201473 29.8691181190012 -0.825363437980594 0.409780153681366 PPP2R2B other 1 1 1 0.0843061558186062 -0.825363437980594 7.53354155410339e-08 2501.13769006297 435.818684381162 5.73894093965808 2.21628559875126e-08 -1886.78720960515 2336.0977532704 -0.807666206161003 0.419884597191884 RPL30 essential 0.000836373783336558 1 0.000283057973821248 5.73894093965808 -0.807666206161003 4.18221518753237e-11 109.516509638102 23.3627649316554 4.68765190928718 4.09583278097754e-06 -154.581051904379 48.935826530239 -3.15885237595525 0.00173505795047027 SUPV3L1 essential 5.29886664260352e-07 1 0.0471553228073944 4.68765190928718 -3.15885237595525 0.0576273217303269 1801.35287329795 2302.74081762084 0.782264708000915 0.434644796946748 -11534.7279121805 5584.71777851228 -2.06540927753976 0.0396993973882125 EEF1A1 essential 1 1 1 0.782264708000915 -2.06540927753976 0.766695621516049 -0.326789167256626 1.89241153713439 -0.172683985932294 0.863009341835668 -7.82405685464413 10.9707454438387 -0.713174587332915 0.476259113119087 FBXO43 other 1 1 1 -0.172683985932294 -0.713174587332915 0.113477646705554 51.9412490867305 24.8177716800321 2.09290542907691 0.0371472768650667 44.9112938500216 51.9852319001619 0.863924083983584 0.388278713591647 HKDC1 other 1 1 1 2.09290542907691 0.863924083983584 9.14396628338178e-09 1329.9474113897 266.860919576007 4.98367244444315 1.02515276725288e-06 -853.959006185664 558.987606466335 -1.52768862190703 0.127580772028658 HK1 other 0.000106362615808297 1 0.0122157203745853 4.98367244444315 -1.52768862190703 2.55157757321139e-06 148.527626788806 45.6476346155145 3.25378583227454 0.00126046858108455 -230.921904392467 94.9760073608108 -2.43137094103359 0.0155904009507565 TYSND1 other 0.025589771481737 1 1 3.25378583227454 -2.43137094103359 0.000610967000460297 457.968382183246 207.454713723028 2.2075583338862 0.0279932733775004 -1357.13851232703 503.129149012174 -2.6973959171151 0.00736347799043962 CD109 other 1 1 1 2.2075583338862 -2.6973959171151 0.0967452046256218 101.885808558345 191.866198078954 0.531025316488619 0.595776637134014 -1372.94221223703 721.694780437202 -1.90238622954333 0.0580354116304497 UBE2L6 other 1 1 1 0.531025316488619 -1.90238622954333 1.23457645712538e-17 804.531913384336 114.268356294945 7.04072360424707 1.19726026138468e-11 -1768.18626518559 418.685689375156 -4.22318295097312 3.15376389504363e-05 ZDHHC5 other 1.75334548440947e-13 0.457989592838235 1.65449395520749e-07 7.04072360424707 -4.22318295097312 1.16045453309553e-15 78.3153856123978 10.068649032603 7.77814236634993 1.05118519298538e-13 -71.0676485630612 36.892096797216 -1.92636512241896 0.0549555043837806 MED19 essential 1.61071089193659e-11 1 1.49562629257961e-09 7.77814236634993 -1.92636512241896 1.31096672455716e-13 346.367266797835 50.5148936173727 6.85673554855741 3.64022490480902e-11 -186.712590445787 117.426414287449 -1.59003910303121 0.11281341820354 ZFAND3 other 1.75774418428624e-09 1 4.98710811958836e-07 6.85673554855741 -1.59003910303121 0.00132590900680411 345.066363119459 112.64000889827 3.06344403284895 0.00237393195174477 -164.166506992823 221.521138906488 -0.741087319265383 0.45918397485061 NPTN other 1 1 1 3.06344403284895 -0.741087319265383 0.514999277991577 25.0523511230722 36.365283600745 0.688908449006539 0.491381620833828 -51.3395334571692 86.0478971853469 -0.596639024735073 0.551171587630538 KAT6B other 1 1 1 0.688908449006539 -0.596639024735073 8.0048387120784e-06 137.847876447876 36.9645779659454 3.72918842938967 0.000227272581247353 -139.315983787625 87.4146644204297 -1.59373698579418 0.111985256309865 SAMD8 other 0.0770785919586029 1 1 3.72918842938967 -1.59373698579418 4.76157926107525e-08 -8.86606964722323 169.535764536879 -0.0522961610574778 0.958328716579806 -1995.85149398142 391.397714975791 -5.09929265709909 6.16567303048876e-07 RAB11FIP1 other 0.000534011114129589 0.00926084089179412 1 -0.0522961610574778 -5.09929265709909 0.278540308263932 -7.46625555265226 15.5263466465552 -0.480876520575996 0.630935983863611 72.8353805199893 55.1409161681654 1.32089536375965 0.187488980792826 GLYATL2 other 1 1 1 -0.480876520575996 1.32089536375965 0.000279924413507576 497.241176680248 133.019832768925 3.73809804395131 0.000219583846362229 -73.6174899155437 308.78692126471 -0.238408704662833 0.811716711937882 MAPK13 other 1 1 1 3.73809804395131 -0.238408704662833 3.74604530365365e-23 123.329778993654 22.0608632538115 5.59043304764362 5.2858822854227e-08 -268.485239674404 51.3556201016783 -5.22796218101999 3.31307839620431e-07 BAG4 other 5.54227402675558e-19 0.00499082129604218 0.000665439720911864 5.59043304764362 -5.22796218101999 0.0262590521328168 -59.0755890028425 29.1713123628658 -2.02512620165981 0.04368429318197 106.557614508173 98.2448301122796 1.08461294488873 0.278909581261419 MS4A1 other 1 1 1 -2.02512620165981 1.08461294488873 5.61055698126019e-11 70.9277401116767 10.0179886246386 7.08003799657295 9.2282141740903e-12 73.7812896865939 56.6476401623959 1.30246007556678 0.193698690045761 TBC1D31 other 7.08052291035036e-07 1 1.27746168811932e-07 7.08003799657295 1.30246007556678 6.98905009969122e-10 40.9378491452566 6.20019020104841 6.60267634020877 1.68683593534856e-10 -27.8647889700484 35.1508022456778 -0.792721280592529 0.428529386215615 WDYHV1 other 8.5014805412644e-06 1 2.28161428615247e-06 6.60267634020877 -0.792721280592529 0.00961278639685962 174.720723913345 59.2579322464837 2.94847824231519 0.00342918549186061 -223.643641647712 335.951606376802 -0.665701956480227 0.506082687279116 ATAD2 other 1 1 1 2.94847824231519 -0.665701956480227 0.000107472832948221 350.342072527142 80.887682794601 4.33121657615992 1.98863703882834e-05 2.68384840300102 466.971298980523 0.00574735194402806 0.995417894336861 FBXO32 other 0.922761743693422 1 0.218590983308011 4.33121657615992 0.00574735194402806 2.27724171461822e-11 67.7631954411791 9.62082361694023 7.04338818995315 1.19020268172039e-11 -77.7797346490516 57.2829747783553 -1.357815912145 0.175497035355796 NSMCE2 essential 2.90325546196676e-07 1 1.64497912640575e-07 7.04338818995315 -1.357815912145 0.264990738643717 15.1289056778961 9.83292457425248 1.53859673830013 0.124909848266571 -2.99545149318692 33.8472609225566 -0.0884990812119361 0.929536430540034 ZNF689 other 1 1 1 1.53859673830013 -0.0884990812119361 0.00198693501794593 63.4892021322163 26.5549539007376 2.39086094329288 0.0173976481032147 -169.453540843989 91.4084560170703 -1.85380596311947 0.064704612628181 PRR14 other 1 1 1 2.39086094329288 -1.85380596311947 4.17620422709505e-10 309.071660451488 64.5255834684258 4.78990880574873 2.57979246156745e-06 -727.771131606403 222.043794191262 -3.27760176435971 0.00116463697357931 FBRS other 5.12378496622292e-06 1 0.0300700609320302 4.78990880574873 -3.27760176435971 0.531824094002207 -14.8147190417161 28.6538947333301 -0.517022875235307 0.605498470096154 -66.5513820206248 59.6227729495671 -1.11620742760352 0.265173433112606 FRRS1 other 1 1 1 -0.517022875235307 -1.11620742760352 0.00866693546369689 40.8922720916291 32.1043660112948 1.27372931386474 0.203704389884021 -260.10822179308 110.476726533455 -2.35441644547926 0.0191692977338119 PHKG2 other 1 1 1 1.27372931386474 -2.35441644547926 0.0145202639197583 125.122742175125 54.2774498546506 2.30524356818883 0.0217963947091145 -101.122766361289 112.9476621978 -0.89530641355106 0.37130048974904 MFSD14A other 1 1 1 2.30524356818883 -0.89530641355106 0.00131126018953304 2.57218286079158 12.0227474572196 0.213943016764192 0.830728605014452 -84.3937939048638 25.0185154631237 -3.37325346219111 0.000834685537113045 SASS6 essential 1 1 1 0.213943016764192 -3.37325346219111 0.144689056391352 166.242624934082 84.4741986100922 1.96796924586889 0.0499654865672488 195.497177895261 295.193778963389 0.662267269255385 0.508293574811044 COX6A2 other 1 1 1 1.96796924586889 0.662267269255385 0.000178701643697201 123.696737294988 29.4439932602301 4.20108564085512 3.45155147981653e-05 59.8360663038496 122.880514255057 0.486945116291186 0.626631637567137 MALSU1 other 1 1 0.373147230482966 4.20108564085512 0.486945116291186 1.17605179847176e-29 188.811185672834 15.169322108109 12.4469099098306 3.04673915486202e-29 210.002877204084 93.9720668083259 2.23473723986964 0.0261289296733493 VPS8 other 1.77607342605205e-25 1 4.62251264575666e-25 12.4469099098306 2.23473723986964 2.62512788930511e-09 84.5596640117954 17.0672349231701 4.95450284667958 1.18216006602688e-06 -74.6533817300162 34.7155554041147 -2.15043028581844 0.0322770997430364 GALK2 other 3.12547726500667e-05 1 0.0140440615843993 4.95450284667958 -2.15043028581844 1.07551236934444e-06 2.28104924676465 7.60043775617974 0.300120771979217 0.76428051376793 -59.9385959248264 12.9451750269125 -4.63018814347559 5.32508285896964e-06 LHFPL4 other 0.0111111182876974 0.0789177279699301 1 0.300120771979217 -4.63018814347559 0.706757633939643 20.4899636117271 34.3023774356211 0.59733362943087 0.550707085534995 -14.5947899565266 59.7466428320661 -0.244277992280656 0.807172075864572 B3GNT7 other 1 1 1 0.59733362943087 -0.244277992280656 0.630862593518321 11.6235647935525 13.2181529736919 0.879363767138034 0.379863931125242 25.512681669358 41.3663922069353 0.616749015522815 0.537838818888317 MPV17L other 1 1 1 0.879363767138034 0.616749015522815 0.00470845976520099 8.39540427786237 43.1190466251561 0.194702919822082 0.845749079471429 -253.894205681742 86.2420417905606 -2.94397257312537 0.00347738734593618 BUB1B other 1 1 1 0.194702919822082 -2.94397257312537 8.96547741553e-08 -12.0538955677042 16.2675399343281 -0.740978391100662 0.459253342360447 -154.233644289931 28.0687385083044 -5.49485486297503 8.02602364073908e-08 PDE6D other 0.000992478349899171 0.00121385581542538 1 -0.740978391100662 -5.49485486297503 2.84731473883484e-31 200.631786574657 22.4429772796604 8.9396243677743 3.21700311608269e-17 -180.130486374607 38.2252020647102 -4.71234883388371 3.6622234665726e-06 BRPF1 other 4.31054978312207e-27 0.0544462762775348 4.70325855571289e-13 8.9396243677743 -4.71234883388371 3.83365302051189e-44 265.490720445836 19.1449114949811 13.8674300226165 1.5132012848271e-34 -63.7574833410033 32.6078889305778 -1.95527786164701 0.0514231508929374 RPUSD3 other 5.86587248668525e-40 1 2.30672403859042e-30 13.8674300226165 -1.95527786164701 4.42393565896768e-25 278.637664432526 41.8675690063873 6.65521478904153 1.22860535638918e-10 -350.451121353741 67.449109688731 -5.19578572602407 3.63783834819173e-07 TATDN2 other 6.59653046108671e-21 0.00547749320087228 1.6668488870132e-06 6.65521478904153 -5.19578572602407 4.93713854140237e-32 630.723990071488 70.0613186516935 9.00245673660671 2.01521772871623e-17 -516.97763717646 112.869547452212 -4.58031106570479 6.65946934311627e-06 SEC13 essential 7.48124603178701e-28 0.0984935515846897 2.94987571129482e-13 9.00245673660671 -4.58031106570479 1.05854104840123e-14 21.1796223737082 6.9776301562285 3.03536041600062 0.00259961976794237 -50.4868880315054 9.99503481099876 -5.05119681783884 7.39114441712821e-07 EXOG other 1.44924854936612e-10 0.011087455740134 1 3.03536041600062 -5.05119681783884 0.00668593843638378 19.9653420791418 17.5109640669056 1.14016235787239 0.255071317787215 -139.295371042534 54.8008037851337 -2.54184905003751 0.0114980824775825 NTAN1 other 1 1 1 1.14016235787239 -2.54184905003751 0.499865178011505 -0.748076853984626 15.9363028765875 -0.0469416815040362 0.962588989308038 -63.3330019973299 53.8216777486432 -1.17671920769743 0.240182157640014 NMNAT2 other 1 1 1 -0.0469416815040362 -1.17671920769743 0.00754731591323836 94.9918366653091 32.4156141129683 2.93043458421805 0.00362911838269776 -35.4971563213919 78.8856619718188 -0.449982359710348 0.653028788199622 ZFYVE9 other 1 1 1 2.93043458421805 -0.449982359710348 0.297245380306616 20.5569225670749 15.0915198793758 1.36215058068261 0.174108405465328 -0.592144436854511 24.3126029017445 -0.0243554521598353 0.980584262249538 ATP2B2 other 1 1 1 1.36215058068261 -0.0243554521598353 0.0708658388180333 -0.286505880682007 5.14984376090942 -0.0556338976449671 0.955668179033199 -17.0882190224338 8.29645439066248 -2.05970143603348 0.0402355999288956 SLC6A1 other 1 1 1 -0.0556338976449671 -2.05970143603348 7.60112809068476e-05 342.604113955982 123.525866678265 2.77354147085912 0.00587032946405463 -953.520646420585 377.892596514259 -2.52325834169817 0.0121113486401181 SMG1 essential 0.66357848231678 1 1 2.77354147085912 -2.52325834169817 1.91279426174049e-05 51.2780105428061 35.8290187953215 1.43118657074421 0.153352614516696 -176.535421587885 49.2844649386829 -3.58196891875607 0.000394011901931116 FCHO2 other 0.177851610456631 1 1 1.43118657074421 -3.58196891875607 0.00075990297056609 28.4388199685314 36.4170526313248 0.780920418146887 0.435428427241672 -184.834839534045 72.940949668451 -2.5340339051548 0.0117539374823254 RBPMS other 1 1 1 0.780920418146887 -2.5340339051548 0.000127890805902117 20.6184014222842 15.4908957837601 1.33100123518355 0.184136134535083 -68.610014421762 21.3084403590534 -3.21985153608914 0.00141422391581502 TMEM171 other 1 1 1 1.33100123518355 -3.21985153608914 0.33565676363858 51.9939695659195 43.0653088987761 1.20732837858263 0.228197338080381 83.5765519890017 61.4167645023289 1.36081007630795 0.174531332812951 KLHL40 other 1 1 1 1.20732837858263 1.36081007630795 0.36898830193673 -2.31122051633933 5.3192261677037 -0.434503148291039 0.664216869288246 8.42186122308943 8.5613771012168 0.983704037740897 0.326006544870839 TIMP4 other 1 1 1 -0.434503148291039 0.983704037740897 0.0155155921007648 10.5604339994854 6.33221176408579 1.66773228579952 0.0963501847068776 29.3913972038768 10.1917931458258 2.88382984067083 0.00419577484077745 SYN2 other 1 1 1 1.66773228579952 2.88382984067083 0.00515111809383267 250.058654745013 104.296638438482 2.39757156595712 0.0170861054023655 -105.389768614983 231.894576697214 -0.454472761355652 0.649801607332571 NRG1 other 1 1 1 2.39757156595712 -0.454472761355652 2.92577361914143e-05 80.1129527664935 17.3378706624584 4.62069156738846 5.57761514170103e-06 -36.8996220753299 56.0327841878178 -0.658536294602908 0.510673097676011 C1orf27 other 0.267679028415249 1 0.0636684768425172 4.62069156738846 -0.658536294602908 0.00161936676571522 42.2733711955598 20.157513213419 2.09715210145159 0.0367694899648362 -117.089546076636 48.7743112897518 -2.4006396601081 0.0169406525721362 CPT2 other 1 1 1 2.09715210145159 -2.4006396601081 6.16269290948771e-07 112.140572663462 61.3419423340067 1.82812229930472 0.0684620815860781 -530.033798397072 122.835421144585 -4.31499150211068 2.12987282702668e-05 NECAP2 other 0.00647390890141684 0.310791042919734 1 1.82812229930472 -4.31499150211068 0.877230384764488 12.599608639601 44.2221070624348 0.284916515212907 0.775893566088025 51.233457005617 107.002425989535 0.478806499308978 0.632405345009283 LRP8 other 1 1 1 0.284916515212907 0.478806499308978 9.03113587650316e-15 98.1561646868583 19.0125142263668 5.16271354320588 4.29860956815647e-07 -137.669778217954 42.4662141669406 -3.24186605560728 0.00131342726065234 PAXIP1 other 1.23771717187476e-10 1 0.00521249396234653 5.16271354320588 -3.24186605560728 0.000601378893661908 57.0949166629507 16.8184964028422 3.39476938338566 0.000774468880284226 -81.0167782699386 72.6599510371421 -1.11501283875797 0.265692181705215 STEAP2 other 1 1 1 3.39476938338566 -1.11501283875797 0.0226960677908053 55.0548042704626 80.9583227794778 0.680038844436368 0.496973075063388 -474.71540048481 193.996899160474 -2.44702571298383 0.014943202671931 SSBP3 essential 1 1 1 0.680038844436368 -2.44702571298383 2.35205838563362e-10 157.23523145602 24.937017667613 6.30529414350257 9.67691095847465e-10 -143.993048639703 107.733916239677 -1.33656190794513 0.182327205022494 CLDN12 other 2.91161307557586e-06 1 1.28838392501131e-05 6.30529414350257 -1.33656190794513 3.06217563330298e-07 3320.82635500836 597.089276678234 5.56169150027781 5.64529109835365e-08 863.51662544752 1636.58034542997 0.527634728022261 0.598118529999837 MMP14 other 0.00328724554235075 1 0.000710064714350922 5.56169150027781 0.527634728022261 0.000597087062241466 242.491540877777 67.2045235502944 3.60826218336778 0.000358560213031635 -189.396741374245 295.5136306734 -0.640906955603565 0.522050609503338 FZD1 other 1 1 1 3.60826218336778 -0.640906955603565 1.86534132862734e-13 156.350989271254 20.7216063809732 7.54531219234129 5.05350898859904e-13 -90.571315562472 89.4676002875193 -1.0123364801493 0.312166675013713 GATAD1 other 2.49452095877334e-09 1 7.11635135774517e-09 7.54531219234129 -1.0123364801493 0.00659504891453081 11.0545517190692 6.08684824122127 1.81613723243594 0.0702849587421852 -27.3549952393136 11.6164186179825 -2.35485618579269 0.0191334645468292 SUSD3 other 1 1 1 1.81613723243594 -2.35485618579269 4.13081445508334e-08 111.956292428892 21.0094384780498 5.32885695854563 1.86859629273088e-07 -78.6134536952161 57.609794672216 -1.36458486169766 0.17334236004057 ZFHX2-AS1 other 0.000464840550630528 1 0.00230117633449808 5.32885695854563 -1.36458486169766 2.61729935193776e-10 116.264779708655 20.1651406093968 5.76563198644279 1.91602259183771e-08 -64.1593391674194 55.0051428388537 -1.16642437154257 0.244311461600232 DDX19B other 3.23498199899507e-06 1 0.00024555745536992 5.76563198644279 -1.16642437154257 0.00786136471078179 65.1237791531588 23.2489726394211 2.80114653508321 0.00540200605076939 152.46969543084 63.4170168043381 2.40423947883354 0.0167741667295801 ST3GAL2 other 1 1 1 2.80114653508321 2.40423947883354 0.0332752133800137 16.3077104043511 11.2218945336746 1.45320474679343 0.147146846299479 -43.8033659307037 30.6103450357139 -1.43099876462017 0.153406394298249 FUK other 1 1 1 1.45320474679343 -1.43099876462017 1.69241136020804e-05 -38.9836089487715 17.3193434464173 -2.25087106040592 0.0250721807919339 141.591788560744 48.0469879359065 2.94694411956945 0.00344503159629464 IL34 other 0.15830815863386 1 1 -2.25087106040592 2.94694411956945 0.0236186215374274 31.7160487788245 60.1636437864727 0.527163030407337 0.598445646613867 -408.283591027472 163.809128834881 -2.49243490842944 0.0131925043479201 DHRS1 other 1 1 1 0.527163030407337 -2.49243490842944 0.000104685523578026 -2.9696096553223 9.01187714331381 -0.329521764233719 0.741976931344252 -49.79326059009 13.0004495114197 -3.83011837754925 0.000154121285498865 CACNA1D other 0.899667389629554 1 1 -0.329521764233719 -3.83011837754925 0.514102410070891 -25.2836256639623 42.453267049743 -0.595563720321857 0.551902663684651 -103.25113000632 90.395395001096 -1.14221670257725 0.25424825148835 KIT other 1 1 1 -0.595563720321857 -1.14221670257725 0.46442305353367 -10.1939636205681 8.23775728242129 -1.23746831462504 0.216826216633633 -9.61834457356417 22.5749860370961 -0.426062038654594 0.670350879559459 HYDIN other 1 1 1 -1.23746831462504 -0.426062038654594 2.81526465816942e-07 34.1721310417705 9.31879599332992 3.66701138926421 0.000287970984014606 -51.1812563355158 19.8612962455419 -2.5769343401745 0.0104228491323266 AASDH other 0.0030292247721903 1 1 3.66701138926421 -2.5769343401745 0.00952569266290211 4.72021005901144 1.69454071437588 2.78553947920333 0.00566244012420739 -0.291041282519181 4.65845421653278 -0.0624759349327251 0.950222830282634 ZNF19 other 1 1 1 2.78553947920333 -0.0624759349327251 0.574733060432109 10.1639923850966 17.810542776721 0.570672803884522 0.568623217979878 27.1694898791717 25.7929553649661 1.05336862312705 0.292969287162833 CACNA2D3 other 1 1 1 0.570672803884522 1.05336862312705 5.30515221259216e-05 108.654600396372 28.1002766074793 3.86667369556967 0.000133722920729762 -42.3799075540416 55.5876568917868 -0.762397804184176 0.446385966923805 RNF111 other 0.471946340832199 1 1 3.86667369556967 -0.762397804184176 0.0179062964953091 67.5881835808868 60.7078573317996 1.11333502039913 0.266402777659827 -246.070475493243 120.091613016273 -2.04902298597572 0.0412776303198988 CCNB2 other 1 1 1 1.11333502039913 -2.04902298597572 0.081691849145898 -14.5256860696989 8.51072149652888 -1.70675142825708 0.0888414064242121 -33.3215269205203 16.835815286056 -1.97920482936863 0.0486524685426143 FAM81A other 1 1 1 -1.70675142825708 -1.97920482936863 0.00303490315622798 244.889328281172 118.358490618066 2.06904740844839 0.039346743295963 -424.135026848536 234.135459184613 -1.81149420222637 0.0710047524740474 MYO1E other 1 1 1 2.06904740844839 -1.81149420222637 1.01879018618981e-13 233.231258330631 69.5173325884073 3.35500873877783 0.000889067035813639 -443.139951430698 100.942728730268 -4.39001359488531 1.54182671422514e-05 APPL1 other 1.36935588925772e-09 0.225877613633983 1 3.35500873877783 -4.39001359488531 0.000225929111367711 172.765475900557 42.7119478730672 4.04489807896345 6.56640849274196e-05 28.7880081685182 61.9088185346739 0.465006583066911 0.642243004419165 AFAP1L1 other 1 1 0.693412736833551 4.04489807896345 0.465006583066911 5.19910787869292e-10 81.5624437882539 33.3006970513312 2.44927136697859 0.0148538041882366 -279.83566471136 55.6565081816706 -5.0279055200146 8.2984353615138e-07 DSCR3 other 6.35902884642931e-06 0.0124451635116622 1 2.44927136697859 -5.0279055200146 4.48552724202017e-08 215.567661386775 67.3009161421072 3.20304200512813 0.00149799169822129 -391.125939191639 110.622014116221 -3.53569714234924 0.000467334584323075 DYRK1A other 0.000503859275096125 1 1 3.20304200512813 -3.53569714234924 0.126507221718561 34.718042154733 91.4957490905634 0.379449783184668 0.704607947857986 -253.345706554635 148.975588564759 -1.70058537103551 0.0900016052618388 KCNJ15 other 1 1 1 0.379449783184668 -1.70058537103551 0.00113860819517278 93.2312646221138 25.2264392946593 3.69577582999801 0.00025819060549954 75.8716898925168 41.0099555768402 1.85007978734228 0.065232489303022 ERG og 1 1 1 3.69577582999801 1.85007978734228 0.00193068528857497 317.848686552742 409.966096582804 0.775304809841862 0.438737534691863 -1934.86450174618 666.471047003087 -2.90314862205443 0.00395340311417173 ETS2 other 1 1 1 0.775304809841862 -2.90314862205443 0.450437784680695 4.65697876716943 85.5477693107521 0.0544371735778751 0.956622270478781 -223.797806895928 203.865295734201 -1.09777294899528 0.273163897683013 TSPAN18 other 1 1 1 0.0544371735778751 -1.09777294899528 0.610715348677491 0.14486469266032 2.90647842831227 0.0498419982234099 0.960279687847554 -4.21883683474627 4.7156920049922 -0.894637908981345 0.371659439949854 LCA5L other 1 1 1 0.0498419982234099 -0.894637908981345 0.00162507621808461 -160.291431667709 692.271088084202 -0.231544310352901 0.817040884121023 -3856.41977603577 1128.53515072476 -3.41719065955467 0.000714963190402175 MX1 other 1 1 1 -0.231544310352901 -3.41719065955467 0.0839503327440222 104.113529573973 57.0620368769678 1.82456735286989 0.0690195136984228 -41.2414386460191 140.739687802627 -0.293033466891415 0.769690748229404 CREB3L1 other 1 1 1 1.82456735286989 -0.293033466891415 8.77483755779996e-07 21.9997146418745 57.9990868071165 0.379311397005912 0.704709003028076 -449.089318398941 94.1754301277052 -4.76864632091364 2.82507552784298e-06 C2CD2 other 0.0091240760926004 0.0420427740053593 1 0.379311397005912 -4.76864632091364 5.95149426884152e-06 450.211484597431 90.0604807463521 4.99899046581169 9.55327725874357e-07 215.968330469131 206.660168571602 1.04504090924664 0.296800290856815 SLC38A10 other 0.0579675541785164 1 0.0114027917360363 4.99899046581169 1.04504090924664 4.15655728783824e-07 15.2151681839606 3.29912261812107 4.61188320203327 5.77769744312479e-06 -17.4883996847387 6.61987070404577 -2.6418038156018 0.00865169927149257 C9orf43 other 0.00441883605270083 1 0.0659004170362814 4.61188320203327 -2.6418038156018 0.0722246295737978 50.2862090996598 29.8642834475043 1.68382439806578 0.0931907695940997 -84.2832743795933 59.9243247297206 -1.4064951880516 0.16054749727977 ZNF618 other 1 1 1 1.68382439806578 -1.4064951880516 0.00142053924159788 27.5514903659331 7.96148692047523 3.46059607220814 0.000612113552720066 9.53383952045015 17.6785197751128 0.5392894677682 0.590062151292439 DGKI other 1 1 1 3.46059607220814 0.5392894677682 0.000503695205441321 47.6555979880265 21.6186828065973 2.20437102548559 0.0282096914876089 -133.109937563842 43.4927766666237 -3.06050677297848 0.00239666316669098 TMEM268 other 1 1 1 2.20437102548559 -3.06050677297848 3.22879985017886e-05 1329.86276180849 394.46206940503 3.37133241686413 0.000839726941268787 -1359.15062232638 771.895128805006 -1.76079699379697 0.0792279121511818 SNX22 other 0.29388536236328 1 1 3.37133241686413 -1.76079699379697 2.69691730144093e-09 91.3089422268035 22.2489570159644 4.10396506053233 5.15908157037228e-05 -125.698421189153 48.9596657787174 -2.56738723988172 0.0107008075011249 UBN2 other 3.20960128044485e-05 1 0.549700141323167 4.10396506053233 -2.56738723988172 1.35435282589157e-08 94.0521118327819 24.655773902953 3.81460797795186 0.000163676888742674 -139.981473744223 54.2559567595929 -2.58002037203911 0.0103249782846169 BRAF og 0.000156143337297039 1 1 3.81460797795186 -2.58002037203911 0.274075308794332 168.905989643164 215.338523188503 0.784374236166314 0.433411876565919 646.747758328908 402.291604453528 1.60765909894503 0.108914876783681 SLC34A2 other 1 1 1 0.784374236166314 1.60765909894503 0.606561255460688 21.2242484502097 21.2279962058651 0.999823452217579 0.318151388316195 10.5741459277928 43.1112443726401 0.245275822622822 0.806400093310793 ACAN other 1 1 1 0.999823452217579 0.245275822622822 0.0267475996389605 129.225204311924 48.1900434210028 2.68157476396055 0.00771135546797109 35.2936940764147 215.634980557948 0.163673324175389 0.870092619318692 PSMG3 essential 1 1 1 2.68157476396055 0.163673324175389 0.0124168629312029 27.6634472776656 15.6232927215286 1.77065409774637 0.0775702102441469 -35.4036416918322 31.2876723581667 -1.13155243018873 0.2586699121844 WDR19 other 1 1 1 1.77065409774637 -1.13155243018873 3.30777154101462e-17 138.95248849917 23.5410657470702 5.90255725854143 9.12301290733822e-09 -187.351345371566 51.8029995844015 -3.61661191194765 0.000346677900202354 SLC37A3 other 4.67355041029955e-13 1 0.00011800617195642 5.90255725854143 -3.61661191194765 7.0166318392267e-06 163.094200368081 39.5757759430944 4.12106134324676 4.80865469854869e-05 -121.577438535227 82.0312700380963 -1.48208650772766 0.13930134554206 AP3S2 other 0.0678999463081968 1 0.51399710072787 4.12106134324676 -1.48208650772766 1.75965823075762e-09 447.087852494575 71.3196832494042 6.26878628906853 1.19668269071099e-09 -147.611352133044 186.303195896485 -0.792317874219727 0.428771638746747 FMNL2 other 2.10666283386302e-05 1 1.58943394980234e-05 6.26878628906853 -0.792317874219727 0.0182352655245654 40.8760400395995 14.791292682535 2.76352046551443 0.00605028569669771 -12.5880211197888 50.6609533592987 -0.248475804047977 0.803926173180624 GAREM2 other 1 1 1 2.76352046551443 -0.248475804047977 8.97168366914901e-11 334.471668007523 67.3766129823731 4.96421017920605 1.12529415707186e-06 -789.478001003228 184.681334782009 -4.27481208068534 2.5296993426165e-05 SPPL3 other 1.12363108006454e-06 0.368349521278388 0.0133831234100556 4.96421017920605 -4.27481208068534 0.585086078948499 -6.63830334557613 10.2740754277868 -0.646121725719714 0.518663613483606 -31.9016677861461 35.7448473935971 -0.892482976213813 0.37280475105455 DPYSL5 other 1 1 1 -0.646121725719714 -0.892482976213813 1.97991608342343e-06 25.5917641770305 12.3927540415312 2.06505866987001 0.0397250977400197 -65.2116122470295 23.1630704419485 -2.81532676811839 0.00517581425437584 RAB28 other 0.020012991771244 1 1 2.06505866987001 -2.81532676811839 1.83007749848599e-05 152.918468784335 40.1059676205971 3.81286072514059 0.000164879126103811 -144.398074128199 88.9600931214858 -1.62317809100094 0.1055390956021 FAM213B other 0.170563222858894 1 1 3.81286072514059 -1.62317809100094 0.0484059525755785 -60.7210990091738 59.6778565955559 -1.01748123128295 0.309698037592887 -324.277116518001 132.327454374425 -2.45056566720045 0.0148015186973817 TNFRSF14 other 1 1 1 -1.01748123128295 -2.45056566720045 1.24796176205312e-09 79.924102575697 15.2864241234628 5.22843680969333 3.10395181496481e-07 -80.9396196838924 33.8955469606507 -2.38791307241199 0.0175277660646854 PANK4 other 1.50217157298334e-05 1 0.00378713160943857 5.22843680969333 -2.38791307241199 0.102996599828657 22.3818794725303 10.7839493614588 2.07548076519368 0.0387404726939994 -5.5395680967756 28.7598744401774 -0.192614474319013 0.847383090737592 C12orf43 other 1 1 1 2.07548076519368 -0.192614474319013 6.91977398320857e-14 231.942839540365 38.9945016327726 5.94809088021349 7.1476562659977e-09 -317.003591823507 86.464954172775 -3.66626681129175 0.000288352038323828 PEX10 other 9.33062323895844e-10 1 9.27908736451821e-05 5.94809088021349 -3.66626681129175 3.34783225886303e-21 617.063666114638 81.6136012962724 7.56079447927538 4.32644936171898e-13 -866.132000657805 180.966956890829 -4.7861334220275 2.6083093148333e-06 RER1 other 4.8982133779425e-17 0.038850767244442 6.09856302027907e-09 7.56079447927538 -4.7861334220275 0.0847068821546479 9.54013132606946 4.42487080501674 2.15602483020594 0.0318314015894732 18.0239887044601 19.9457670689384 0.903649814126673 0.366865143754895 RADIL other 1 1 1 2.15602483020594 0.903649814126673 1.45151833302239e-09 566.140086421114 87.8522676192537 6.44422849589643 4.30167427367647e-10 91.8203523255172 195.275551598515 0.470209156107258 0.638527905718575 SKI other 1.74312836612659e-05 1 5.7745675449833e-06 6.44422849589643 0.470209156107258 1.32670871877792e-21 417.726301723861 40.4305939753984 10.3319358102442 9.10329581775432e-22 -124.854608238743 182.103056837403 -0.685626097700402 0.493448436176972 WIPI2 other 1.94614901957533e-17 1 1.36085169179609e-17 10.3319358102442 -0.685626097700402 3.68911669330088e-08 67.6633257406798 50.2178087696919 1.34739701708205 0.178808634656151 -520.212705533359 98.5028934377145 -5.28119212926776 2.38011720914788e-07 LDLRAP1 other 0.000416464383506736 0.003589216751395 1 1.34739701708205 -5.28119212926776 0.00669407864714541 46.6718813766835 44.5445086288722 1.04775836154207 0.295543145651837 -178.269215072779 79.7368763156715 -2.23571856974966 0.0260616530932515 AGAP1 other 1 1 1 1.04775836154207 -2.23571856974966 0.0100773548773412 128.456283860722 42.8598021797923 2.9971273157506 0.00293859866164538 -32.2463325226968 152.059509946347 -0.212063898759603 0.832192191857057 KRTCAP3 other 1 1 1 2.9971273157506 -0.212063898759603 5.7465261375538e-07 30.659235036792 13.6924455328765 2.23913507365627 0.0258361323831074 -113.359713128914 26.8579122878945 -4.22071946299443 3.17879248132738e-05 PAFAH2 other 0.00604994271761664 0.461592456213548 1 2.23913507365627 -4.22071946299443 0.532392320216093 8.80694984816009 9.49872595456309 0.927171695476626 0.354538346851376 -6.76253558809602 18.6318760897643 -0.362955161118268 0.716878756047356 EXTL1 other 1 1 1 0.927171695476626 -0.362955161118268 0.110538079973481 127.680016374833 63.7859551887818 2.00169482446331 0.0461640666213074 -12.0994949115406 125.021152992924 -0.0967795818698409 0.922962212873432 TRIM63 other 1 1 1 2.00169482446331 -0.0967795818698409 0.241405104463602 100.829627764488 73.9620447337116 1.36326176659271 0.173758411118869 -152.964245247388 194.669720098413 -0.785762907400588 0.432587823368454 WDR66 other 1 1 1 1.36326176659271 -0.785762907400588 8.26881904635274e-09 227.823460602363 52.2415560836815 4.36096237710513 1.74824471511232e-05 -194.491445869259 104.218655251639 -1.86618648455647 0.0629298921194261 MRPL17 essential 9.63813548042875e-05 1 0.192901321865494 4.36096237710513 -1.86618648455647 0.108341155399145 55.0066812330921 38.8381148401286 1.41630667347061 0.157706201498613 -173.682897826927 129.045074852574 -1.34590876889605 0.179331503742989 DUSP2 other 1 1 1 1.41630667347061 -1.34590876889605 0.018770131077387 153.939012343558 151.694904325275 1.01479356230366 0.31097329945813 -672.684718804736 295.53343805044 -2.276171262522 0.023498191223744 GRHL3 other 1 1 1 1.01479356230366 -2.276171262522 0.00717617500226856 170.517596239359 130.374201214782 1.30790903913915 0.19184294386304 -621.096650596125 255.738802242914 -2.42863673853518 0.0157062551421777 UBXN11 other 1 1 1 1.30790903913915 -2.42863673853518 4.05992127531733e-06 42.9694849119674 8.7150081967124 4.9305157197875 1.31956541330096e-06 -9.0291841404763 16.6321188667993 -0.542876359457735 0.587592844792945 PTPDC1 other 0.0400511233810054 1 0.0156381697130296 4.9305157197875 -0.542876359457735 0.00016760434960425 171.887358916478 42.6700720588276 4.02828846127806 7.02843168515534e-05 -95.2914221218963 148.325744399822 -0.642446950173612 0.521044468827466 GALNT14 other 1 1 0.74023442508056 4.02828846127806 -0.642446950173612 1.13010479796825e-05 237.180707803818 49.2371667847046 4.81710714267779 2.2550430287845e-06 -20.7508196616434 218.924418477079 -0.0947853136072899 0.924544862672061 NCK1 other 0.107303450567085 1 0.0263614530064907 4.81710714267779 -0.0947853136072899 0.948783222753634 -2.40374880633457 15.6791759096318 -0.153308363920959 0.878251734397218 -23.1460649215646 77.1425362396055 -0.300042830451836 0.764339299186363 RHPN1 other 1 1 1 -0.153308363920959 -0.300042830451836 2.64642919006595e-17 593.616130445412 78.2192625758816 7.58912972197273 3.54788183745674e-13 -500.361226597767 171.794316766794 -2.91255983326266 0.00383682395819384 TPRG1L other 3.74416801810531e-13 1 5.00748042538644e-09 7.58912972197273 -2.91255983326266 1.33569022596909e-07 73.9168695010978 12.8788269041713 5.73941012260653 2.21623844207053e-08 4.51617932765677 24.497115128127 0.184355557951858 0.853852040095011 AAED1 other 0.00146311507352654 1 0.000283057973821248 5.73941012260653 0.184355557951858 0.720018839864178 60.6664278892074 78.9659339681034 0.768260752968645 0.442900632832934 102.905111913957 274.584876685137 0.374766131173194 0.708083426121866 XDH other 1 1 1 0.768260752968645 0.374766131173194 0.000102161882908581 17.0420577305045 7.50613543661125 2.27041703076415 0.0238467747099766 -46.0794717685454 15.0523445261817 -3.06128202742076 0.0023906441699411 XKR8 other 0.879103002428336 1 1 2.27041703076415 -3.06128202742076 0.000217764251221167 124.366663374368 30.6515191500798 4.05743880965338 6.3084487916988e-05 -33.4392924948543 101.490130111882 -0.329483196622088 0.742016646865277 CNNM4 other 1 1 0.667118459722148 4.05743880965338 -0.329483196622088 2.47769679419439e-06 90.226423882703 33.1255892529379 2.72376811756491 0.0068085633348989 -241.500615499268 66.4280289476247 -3.63552282560845 0.000323148573224135 EYA3 other 0.0248661650265349 1 1 2.72376811756491 -3.63552282560845 8.27115476584078e-06 43.463615806045 8.82246818748909 4.92646897471159 1.34903317845148e-06 17.133547772924 40.1128218628341 0.427133943144468 0.669570826663358 DZIP1L other 0.079535424228325 1 0.0159819960651147 4.92646897471159 0.427133943144468 9.14422376387058e-09 64.1202496050262 20.4638022294571 3.13334975025935 0.00188969250762534 -197.319507384628 39.5213573759725 -4.99273103166721 9.84486802188778e-07 FANCC other 0.000106362615808297 0.0147545037044032 1 3.13334975025935 -4.99273103166721 0.0191312589128317 41.8895579053002 15.5730074016163 2.68988236022752 0.00752503890951591 -40.1618696611 70.8267076335323 -0.567044142005066 0.571084230937344 MRAS other 1 1 1 2.68988236022752 -0.567044142005066 0.016329881906158 578.405648491152 301.716241644877 1.91705174815196 0.0561216076810535 -978.959575632497 604.21209853471 -1.62022504681153 0.106168929616842 WASF2 other 1 1 1 1.91705174815196 -1.62022504681153 8.75938462082736e-05 147.950143903698 34.61601973294 4.2740368489827 2.74310398122349e-05 57.8807490157623 80.7809871644894 0.716514504804246 0.474350635434868 ABHD3 other 0.759175865087108 1 0.298532006276553 4.2740368489827 0.716514504804246 0.00301172747041752 24.3654794549388 7.16577210917009 3.40025876956904 0.000759063809136481 -3.90564982604981 32.5902398333179 -0.119841088805274 0.904684708614822 ESYT3 other 1 1 1 3.40025876956904 -0.119841088805274 5.38984741511495e-05 48.6051139403956 10.8010839542565 4.5000218631984 9.54254336814261e-06 33.3459120407166 49.1237945006025 0.678813849372071 0.497749534852452 FAIM other 0.478995739781266 1 0.107305900174764 4.5000218631984 0.678813849372071 0.000681786800339217 277.43131541482 142.337329394892 1.94911142842318 0.0521555989535971 -760.948229206923 279.811431876221 -2.71950371757341 0.00689493082484913 FAM46B other 1 1 1 1.94911142842318 -2.71950371757341 0.0806863286452513 35.667912406247 17.677581308563 2.01769188802822 0.0444603454525349 -65.9216597659988 85.6733245499581 -0.769453737348063 0.442193360808852 CLSTN2 other 1 1 1 2.01769188802822 -0.769453737348063 0.858450493233835 -10.1783927126848 23.0107419130615 -0.442332226885185 0.658577389650788 26.6865693470689 101.764909469197 0.262237440059304 0.793323929140021 COLEC12 other 1 1 1 -0.442332226885185 0.262237440059304 0.020934394193295 -22.0247556251938 18.1013188221328 -1.21674867127713 0.224599305765731 -109.336306659561 39.3946881216039 -2.77540734228079 0.0058385824077683 RNF207 other 1 1 1 -1.21674867127713 -2.77540734228079 2.04587109612222e-06 415.57831327697 107.919048160483 3.85083375326826 0.000142261367556091 -498.980343493885 234.868922338646 -2.12450561157866 0.0343966161661293 GPR153 other 0.0206346558754887 1 1 3.85083375326826 -2.12450561157866 0.00587926849803905 12.9964527090102 4.379306815366 2.96769631746479 0.00322663690370602 38.8504984877338 19.9093267306977 1.95137178736593 0.0518850938878643 SLC13A3 other 1 1 1 2.96769631746479 1.95137178736593 0.00436783383883036 10.5900745593926 20.525465289553 0.515948087412309 0.606249210667788 -162.743358260747 51.3822739633145 -3.16730548704289 0.00168786026885891 RHBDL2 other 1 1 1 0.515948087412309 -3.16730548704289 0.0264060617307638 61.9481731114719 61.163314548297 1.01283217838947 0.311930186185196 -482.284010853538 220.225684269967 -2.18995351269892 0.0292724816339707 AUTS2 other 1 1 1 1.01283217838947 -2.18995351269892 9.24335146657676e-05 130.842810405551 32.7472113767762 3.99554053321141 8.01534728057967e-05 -5.93848473981042 71.474387993298 -0.0830854926714065 0.933835509613183 HIST1H2BD other 0.799642335373556 1 0.839126706803885 3.99554053321141 -0.0830854926714065 1.08397066704415e-05 32.2990588742026 15.9907867581408 2.01985426750559 0.0442315732959178 -82.2100912590517 23.4797779129714 -3.50131468720727 0.000528736830551862 CDC25C other 0.103074770729228 1 1 2.01985426750559 -3.50131468720727 0.00107295971999505 58.4468249339747 16.2408283054329 3.59875887084053 0.000370360393995248 15.759500777447 35.4746473893028 0.444246861836297 0.65716439167383 HIST1H4H other 1 1 1 3.59875887084053 0.444246861836297 0.199193367794294 4.41697236752534 12.5898374194491 0.350836330952287 0.725944174310587 -66.208902428935 39.5970878742746 -1.6720649417239 0.0954982111225692 MITD1 other 1 1 1 0.350836330952287 -1.6720649417239 3.7726411390418e-08 721.478266031625 126.048145698796 5.72383085869161 2.41462430097275e-08 -281.61778810808 390.450023957334 -0.721264619870668 0.471278328658963 EIF5B other 0.000425591646895306 1 0.000308033622075094 5.72383085869161 -0.721264619870668 4.78271551719151e-10 203.452776517221 32.9436293911154 6.17578512985854 2.00253526195416e-09 -166.923154005019 104.028446244151 -1.60459143658896 0.109573270425232 CNOT11 other 5.85786996545617e-06 1 2.64414755988427e-05 6.17578512985854 -1.60459143658896 0.95344110377421 0.460361230524368 5.33308920697243 0.0863216819854609 0.931264689533735 -6.58232513867978 24.6200911824206 -0.267355839176572 0.789367424846045 KCNB1 other 1 1 1 0.0863216819854609 -0.267355839176572 0.299927596167683 -13.3403108580675 44.966924315457 -0.296669408930019 0.766911375346263 -155.821630357504 104.101700310424 -1.49682118440769 0.135425442587796 TSPAN33 other 1 1 1 -0.296669408930019 -1.49682118440769 2.46002082553934e-05 94.1831443021881 36.4286496116858 2.58541409868719 0.0101681451968534 -196.353423542672 84.3349733680942 -2.32825618721256 0.0205213087917978 AHCYL2 other 0.226494117407407 1 1 2.58541409868719 -2.32825618721256 0.00448162424211972 296.980043846989 91.7888648929788 3.23546918456016 0.00134142116825331 26.884097898933 423.74131305389 0.0634445995014746 0.94945208528985 B4GALT5 other 1 1 1 3.23546918456016 0.0634445995014746 0.117710290644795 3.99978060211918 2.03793639131347 1.96266214155059 0.0505542501610541 4.31187408755622 7.03189210768445 0.613188317102334 0.540188765322856 CD1D other 1 1 1 1.96266214155059 0.613188317102334 0.513646411768919 -22.4728987232687 21.0407770395551 -1.06806410623625 0.286296657517018 -29.7528182239337 72.8031773174627 -0.408674721629177 0.683051739019537 CD1A other 1 1 1 -1.06806410623625 -0.408674721629177 2.24371133844609e-14 68.3615098343645 9.63591508754511 7.0944491740826 8.38992558487912e-12 -113.624301529964 44.4839939619352 -2.5542738277321 0.0111038061436076 SPATA2 other 3.05212053368821e-10 1 1.16217249201746e-07 7.0944491740826 -2.5542738277321 0.583925914992266 3.04951007985176 3.20377234291022 0.951849804996341 0.3418915456422 4.27496029602161 11.0853703514463 0.38563982622952 0.700019669148145 CD1C other 1 1 1 0.951849804996341 0.38563982622952 2.12986407242276e-66 92.3898167116238 4.18270888824292 22.0885122967367 1.07345557264526e-63 -4.14580426016018 25.1172514533342 -0.165058038609947 0.869015313379767 FAM86C1 other 3.26998031039066e-62 1 1.647968995125e-59 22.0885122967367 -0.165058038609947 0.510478737388153 0.331317529029077 1.34503222729296 0.246326833146515 0.805587172216732 -5.31171302458046 4.65394503051021 -1.14133557439077 0.254583682406648 CD1B other 1 1 1 0.246326833146515 -1.14133557439077 0.482727487513739 -5.8395625474605 12.1501727433447 -0.48061559870901 0.631119166398004 -44.8097008456458 37.4295091191286 -1.1971757551783 0.232126935248658 DNAH3 other 1 1 1 -0.48061559870901 -1.1971757551783 0.865603043480651 -0.56882045559834 4.01233555395604 -0.141767917450848 0.887352536129428 -7.13393384798685 13.8830793293743 -0.51385817791105 0.60770578842409 CD1E other 1 1 1 -0.141767917450848 -0.51385817791105 0.236856993154884 -14.9647402658621 9.96945167309464 -1.50105951225469 0.134338682601852 -40.6186529390156 34.504381567993 -1.17720275203235 0.240000492751956 NCF1 other 1 1 1 -1.50105951225469 -1.17720275203235 0.879196473872156 -3.21238065164976 7.21683303008214 -0.445123316316103 0.656538314530504 4.331298349868 31.5948326371121 0.137088820808639 0.891048727419209 PPP1R9A other 1 1 1 -0.445123316316103 0.137088820808639 7.36508696092774e-14 185.639116313697 35.5540521789885 5.22132091664658 3.20454571000972e-07 -289.410373741772 90.4613978564354 -3.19926930823105 0.00151576375387171 ZC3H18 essential 9.92519118854623e-10 1 0.00390570031135985 5.22132091664658 -3.19926930823105 0.000103456559687789 -4.19674965191579 56.3361022454251 -0.0744948529387581 0.940663182700182 -384.348824505188 98.8842758322618 -3.88685482368462 0.00012347249502933 ZFAND2B other 0.889519500195607 1 1 -0.0744948529387581 -3.88685482368462 4.25018658685045e-08 74.8230102037268 13.1368499211217 5.6956584457454 2.81940328355905e-08 44.5761915571545 40.8400263141602 1.09148292937556 0.275894576670464 GDPD5 other 0.000478103489154807 1 0.000358712679767219 5.6956584457454 1.09148292937556 9.90159929439674e-05 40.1192303922331 9.20615177803673 4.35787192732866 1.7831507046181e-05 36.5761147137575 39.247873645247 0.931926020868318 0.352093028755478 DYNC1I1 other 0.854012939141719 1 0.196645859705284 4.35787192732866 0.931926020868318 3.30829087580907e-08 220.919775171929 40.9910178617363 5.38946790531273 1.37356919814414e-07 -268.814353481729 164.385411603286 -1.63526891382833 0.102975917484758 TMED4 other 0.000374465444232828 1 0.00170089073806188 5.38946790531273 -1.63526891382833 0.0005840084136655 222.785498871047 59.27218240041 3.75868560678315 0.000202986601977803 -200.013329017522 201.290225418983 -0.993656441097411 0.321140917861258 PPP1R15B essential 1 1 1 3.75868560678315 -0.993656441097411 4.61829767783804e-14 165.148142355216 33.8659464359265 4.87652523361992 1.70407003224571e-06 -280.400781282783 76.8926897938012 -3.64665070287849 0.000310013623459323 COPG2 other 6.24024382229476e-10 1 0.0200586083495643 4.87652523361992 -3.64665070287849 3.19130904025288e-11 66.9222566973123 16.9833686054755 3.94045835381187 0.000100276521510444 -181.408383342191 52.8791912969048 -3.43061947229153 0.000682752309027665 EMSY other 4.05391987383323e-07 1 1 3.94045835381187 -3.43061947229153 1.30573406910744e-29 260.331211731382 37.738819617653 6.89823408280654 3.61730057232475e-11 -535.694756914368 91.7524915245431 -5.83847640552708 1.48171490485096e-08 GPAT4 other 1.97152787094532e-25 0.000224983591152569 4.95642524419938e-07 6.89823408280654 -5.83847640552708 0.928093508150618 0.0900656893632529 0.505297339350402 0.178242951920228 0.858645317736214 -0.916882327096597 2.90602486862127 -0.315510833027249 0.752580135475085 PKD1L1 other 1 1 1 0.178242951920228 -0.315510833027249 0.0092418002875867 17.5415656375931 6.20444407335698 2.8272582410598 0.00499048014448185 -0.31255355446411 14.039597067605 -0.0222622880812796 0.982252606302713 ZSCAN12 other 1 1 1 2.8272582410598 -0.0222622880812796 0.00126377634534565 2021.37769015993 653.697845286527 3.09222021264875 0.00216149359960844 -4803.07003695493 2288.17826808435 -2.09908034874225 0.0365929876688032 TAGLN2 other 1 1 1 3.09222021264875 -2.09908034874225 0.0402661845669037 139.764404023179 55.8902522131373 2.50069374334164 0.0128947167388208 100.05255027658 189.805082436587 0.527133146237044 0.598466373672975 ELK4 og 1 1 1 2.50069374334164 0.527133146237044 0.626997403106326 -19.6845397567832 30.7022786343774 -0.641142632805839 0.521888927853159 -75.0920891749517 106.52439976219 -0.704928536021708 0.481367465969905 SLAMF8 other 1 1 1 -0.641142632805839 -0.704928536021708 0.00950211182183705 19.8835993873652 7.33140528154579 2.7121129747683 0.00704696139998973 -34.9019494839448 24.8976866043331 -1.40181495729288 0.161939722490548 SLC45A3 other 1 1 1 2.7121129747683 -1.40181495729288 0.000680504675798464 172.816940322604 45.0137673049906 3.83920188576271 0.000148772672735769 -84.2421345028051 156.179435419167 -0.539393257996542 0.589990632057669 DUSP23 other 1 1 1 3.83920188576271 -0.539393257996542 0.531681592784041 -2.32504426298794 13.4407222449043 -0.172985068854422 0.862772527414555 31.1396967476223 34.1976919073285 0.910578901991603 0.36320267244619 RNF166 other 1 1 1 -0.172985068854422 0.910578901991603 0.000617148959178142 725.763442904136 253.765333370122 2.85997867898526 0.00451507658288561 -797.39880562903 492.084304745188 -1.62045161355419 0.106120263196051 NBL1 other 1 1 1 2.85997867898526 -1.62045161355419 1.27813582291727e-06 2139.17361385134 402.082075106384 5.32024118032456 1.95540009374545e-07 -435.057728689181 1381.47254638558 -0.314923180940111 0.753025873397129 F11R other 0.013131567444652 1 0.0024059242753444 5.32024118032456 -0.314923180940111 0.130295239003293 78.487341655449 39.0720539109988 2.00878463758863 0.0454022889135667 26.4498736931388 134.243661060147 0.197028846533678 0.843930438103513 USF1 other 1 1 1 2.00878463758863 0.197028846533678 0.0826542178048526 59.9601933533032 27.7039657934774 2.16431805468877 0.0311815582152927 2.85132409932255 54.0135097310396 0.0527890913499369 0.957932995185472 PLA2G2F other 1 1 1 2.16431805468877 0.0527890913499369 5.70563894158892e-05 44.8702904736635 14.9468936139045 3.0019809890078 0.00289410166616162 -63.3894098973724 38.1663601738461 -1.66087123866768 0.0977218063701544 SPATA2L other 0.505621115375122 1 1 3.0019809890078 -1.66087123866768 3.57132695966216e-07 99.7170477497125 18.605952091722 5.35941655971895 1.60675127003203e-07 -109.087655355806 63.877518982634 -1.70776287328039 0.0886563104184382 NIT1 other 0.00382131984683851 1 0.00198417714336255 5.35941655971895 -1.70776287328039 1.73258323299104e-21 223.123833803403 21.2713962993557 10.4893835206371 2.65156625805981e-22 -112.611272125592 73.0284596134026 -1.54201899809653 0.124063472289023 DEDD other 2.53944724459497e-17 1 3.96965984494135e-18 10.4893835206371 -1.54201899809653 0.101467503886446 16.861223265579 26.9309988173339 0.626089785230187 0.531703768515532 -107.486274390538 68.7673457277846 -1.56304236048345 0.11903409735218 ZNF276 other 1 1 1 0.626089785230187 -1.56304236048345 9.56331899414592e-06 12.8229296716277 9.43465066657146 1.35913136848421 0.175062049096552 -48.8071426662845 17.4466123280028 -2.79751402442447 0.00546163216842797 NPM2 other 0.0914225654211737 1 1 1.35913136848421 -2.79751402442447 0.00404521182748217 192.877632919192 92.4230471761708 2.08689973780611 0.0376907945492986 -346.709338689294 180.059448987838 -1.92552704475238 0.0550521537994014 CDA other 1 1 1 2.08689973780611 -1.92552704475238 2.78288218377293e-15 251.427240316674 29.2042740843515 8.60926176731771 3.45849754275466e-16 -95.7230938567145 100.186875499634 -0.955445445117852 0.340078230027277 B4GALT3 other 3.84204714291690e-11 1 5.02485107986825e-12 8.60926176731771 -0.955445445117852 1.25979162152947e-07 86.6912688665039 68.5413499162811 1.26480247284875 0.206862471967592 -454.268189285584 126.747073388134 -3.58405268967821 0.000391001329229718 DMTN other 0.00138211738797998 1 1 1.26480247284875 -3.58405268967821 0.0647186021557036 120.005019909337 57.5529236885308 2.08512465081339 0.03785524110296 -225.842479811083 197.438483955072 -1.14386250991713 0.253540974016986 ADAMTS4 other 1 1 1 2.08512465081339 -1.14386250991713 4.34221092299203e-30 187.937760924629 47.3724520649765 3.96723734432939 8.97822984047452e-05 -621.512531753218 87.6014211244647 -7.09477681726383 8.37277058449275e-12 FAM160B2 other 6.56368603119475e-26 1.28245727042675e-07 0.935441767079041 3.96723734432939 -7.09477681726383 3.00604636061459e-11 455.756889846446 63.4622765799698 7.18154019060661 4.91256226867216e-12 -235.896739657516 217.710845483662 -1.08353232992804 0.279393060735995 NDUFS2 essential 3.82188734288539e-07 1 6.82797029722744e-08 7.18154019060661 -1.08353232992804 0.854606976487223 -15.7843035258623 36.8743432193314 -0.428056533291348 0.668899720341916 -44.2260945263123 126.499471364209 -0.3496148564841 0.726859176282897 FCER1G other 1 1 1 -0.428056533291348 -0.3496148564841 0.449687457107829 13.9971630383638 11.5619337850909 1.21062473618497 0.226932658338887 -16.0833716240365 39.6948344284336 -0.405175430395948 0.68561929934065 MPZ other 1 1 1 1.21062473618497 -0.405175430395948 7.0048051414601e-46 717.26725315874 92.6385105221486 7.7426466500371 1.29151342772147e-13 -1195.42806519349 171.307686616325 -6.97825117369583 1.7266740143875e-11 CCAR2 other 1.0722255230033e-41 2.6437105834287e-07 1.83485312676389e-09 7.7426466500371 -6.97825117369583 0.00513284040609118 25.4041183413189 31.9377699963451 0.795425552385973 0.426955607749021 243.374448381973 74.3549126751483 3.27314550748327 0.00117984913780716 CACHD1 other 1 1 1 0.795425552385973 3.27314550748327 8.76979029364139e-11 142.369087780851 54.6776814885444 2.6037879424474 0.00964975982254975 -417.114618826328 82.3953534507227 -5.06235608389965 7.00154055026591e-07 CDC42SE2 other 1.09903011959914e-06 0.010506511749729 1 2.6037879424474 -5.06235608389965 2.50007054728672e-06 37.6755870049255 18.8223584921089 2.00164007187095 0.046167342146393 -103.495331265603 28.363947382415 -3.64883384777985 0.000307496362452854 RAPGEF6 other 0.025085707871475 1 1 2.00164007187095 -3.64883384777985 0.209505381270012 25.3072898190859 41.9728469336648 0.602944323959781 0.54697548456322 -126.42750175629 85.0419612606873 -1.48664847190835 0.138098462320685 EPB41 other 1 1 1 0.602944323959781 -1.48664847190835 1.21634227656009e-07 34.2445259164111 23.4207107860719 1.46214716663407 0.144704176073974 -183.462068332382 38.4732065488483 -4.76856713514237 2.84797089947923e-06 MIS18A other 0.00133554381966298 0.0423806549551504 1 1.46214716663407 -4.76856713514237 1.49494868278604e-33 199.159905492155 18.6291254976951 10.6907812455714 5.64627151865711e-23 -169.903535282109 60.3282262170555 -2.81631909200863 0.00516315989446883 ALG8 other 2.26948159533748e-29 1 8.46884265083379e-19 10.6907812455714 -2.81631909200863 3.23351179459231e-08 291.21447581122 131.209613783231 2.21945989637872 0.0271584551636727 -1457.84725109591 276.070531663799 -5.28070577583879 2.38593411917848e-07 FBXW5 other 0.000366227545855525 0.00359775005830924 1 2.21945989637872 -5.28070577583879 2.71836084893173e-08 111.06365661412 36.6531693087574 3.03012423505718 0.00264704965476503 -237.494097454184 60.0271690112938 -3.95644341330674 9.40373013130914e-05 C21orf59 other 0.000309077628523537 1 1 3.03012423505718 -3.95644341330674 0.000941195379536336 13.0406956819741 16.2397333190339 0.803011689033691 0.422573455718907 -85.4609379292794 26.595932494358 -3.21330857443742 0.00144798049601882 SYNJ1 other 1 1 1 0.803011689033691 -3.21330857443742 0.00149519107048433 19.6812028786843 29.5966020020626 0.664981840729984 0.506548660819703 -153.168798061212 48.4705760522961 -3.16003667660055 0.00173069133799346 PAXBP1 essential 1 1 1 0.664981840729984 -3.16003667660055 3.34697650642948e-05 27.9330147338107 35.5947139289996 0.784751769308452 0.433188897720933 -239.616341618622 59.2168062510173 -4.04642460120019 6.54862584517976e-05 IFNAR2 other 0.304139755139247 0.940906561435428 1 0.784751769308452 -4.04642460120019 2.91749924666665e-09 152.696659998726 24.3037950071623 6.28283195911282 1.08912305085091e-09 -58.7186270017207 57.8153239477861 -1.01562393829619 0.310578176500753 MRPL10 essential 3.46715610473864e-05 1 1.44820692071645e-05 6.28283195911282 -1.01562393829619 6.39049953471932e-08 333.998435152313 119.906143017698 2.78549894731429 0.00567035541482313 -815.143886057972 199.603796421077 -4.08380953004708 5.63199034989329e-05 IFNGR2 other 0.000712221173144469 0.810950290481135 1 2.78549894731429 -4.08380953004708 4.36649747054014e-08 290.734213047534 88.7834034143797 3.27464595708938 0.00117686963916971 -558.515728830015 149.91935965578 -3.72544099782968 0.000231375820028835 GART other 0.000490663320764596 1 1 3.27464595708938 -3.72544099782968 2.43318623099772e-06 66.8086163453859 34.9369159091343 1.91226427997094 0.0567608242230112 -237.885202319185 59.025744231214 -4.03019403512047 7.01348688969617e-05 DONSON essential 0.0244364893179101 1 1 1.91226427997094 -4.03019403512047 9.47893884631131e-10 117.807794419535 17.6767841498256 6.66454901643955 1.18719049923421e-10 -13.6888470494171 73.1994459600337 -0.187007522664736 0.851775123456161 SV2A other 1.14685681101521e-05 1 1.61125494556067e-06 6.66454901643955 -0.187007522664736 0.0476883525311542 1059.2998622672 429.577257545125 2.46591234443067 0.0141922077365923 -282.496268809937 1432.13030309687 -0.197255981665258 0.843752848056798 LAD1 other 1 1 1 2.46591234443067 -0.197255981665258 0.549928813457402 -55.8747896266083 139.826877896141 -0.399599779865715 0.689717897335385 -269.705082704066 258.533147341958 -1.04321277745995 0.297637212296388 STC1 other 1 1 1 -0.399599779865715 -1.04321277745995 0.70238596004462 296.731564764356 364.203415436596 0.814741301666934 0.415828229332476 -231.040495153688 1214.18612968201 -0.19028424844072 0.849207428406888 TNNI1 other 1 1 1 0.814741301666934 -0.19028424844072 0.00875300589308507 442.771650997063 162.310743800338 2.72792570984534 0.00672641726310802 -765.117427476413 541.113689404842 -1.4139679746745 0.15834648376268 CSRP1 other 1 1 1 2.72792570984534 -1.4139679746745 0.94644329565123 -2.89412211565832 18.6989980412386 -0.154774181444142 0.877097533649908 12.636644193334 44.5991024911263 0.283338531214798 0.777101709068463 HOXB13 other 1 1 1 -0.154774181444142 0.283338531214798 0.546679259603437 -276.90474660615 255.015123766271 -1.0858365673243 0.278368599198866 -240.213036761589 493.045399670838 -0.48720267326692 0.626448280710583 C1QC other 1 1 1 -1.0858365673243 -0.48720267326692 0.468397805168635 98.643826241224 80.0789581132479 1.23183203884498 0.218921934365823 25.2050334552341 190.996846590332 0.13196570469719 0.895094874049107 ATP5G1 other 1 1 1 1.23183203884498 0.13196570469719 0.0279452081061021 263.939901834384 130.372959204085 2.02449881820365 0.0437704437828224 -231.500085197501 220.407859743452 -1.05032590701148 0.29438115556582 RCAN1 other 1 1 1 2.02449881820365 -1.05032590701148 5.18104546004309e-07 433.783784691421 98.3792473542804 4.40930172121862 1.42058826302762e-05 -707.604303554431 234.644986115138 -3.01563785900465 0.00277103767403569 UBE2Z other 0.00547170211035151 1 0.157671091313435 4.40930172121862 -3.01563785900465 0.0946472439252222 22.4376959600113 11.5315874994291 1.94575950285442 0.0525700081084243 -48.7464542481559 47.7505093800532 -1.02085726165088 0.308102973323236 CIART other 1 1 1 1.94575950285442 -1.02085726165088 0.013227913763486 160.884465376322 54.9091015520135 2.93001452999411 0.00363467953537466 -32.3303823091406 130.964057133604 -0.246864544492223 0.805172347389614 SNF8 essential 1 1 1 2.93001452999411 -0.246864544492223 0.301251779436951 -38.7038388031335 59.6436491686359 -0.648918021325333 0.516865689471889 -154.662321224225 100.304900931753 -1.54192187806912 0.124099733533264 CLIC6 other 1 1 1 -0.648918021325333 -1.54192187806912 0.000633940616256107 55.0942746162371 16.423144084344 3.35467279184123 0.000890110266009341 -70.0136853312964 51.5047159032082 -1.35936455727417 0.174988255178793 CCDC24 other 1 1 1 3.35467279184123 -1.35936455727417 0.00572691020965433 90.8019911017653 40.7403096838112 2.22879972701452 0.026525800115557 241.453011550104 97.169979006435 2.48485194726773 0.0134745209305582 IGF2BP1 other 1 1 1 2.22879972701452 2.48485194726773 0.045388559692314 560.302233880826 326.006503620656 1.71868422150497 0.086651289810593 -618.708669171163 543.161505298823 -1.13908784612926 0.255529275142985 CBR1 other 1 1 1 1.71868422150497 -1.13908784612926 0.0125158666239845 -52.4477316950705 66.8365722475369 -0.784716060853993 0.43320794257386 -331.033113204529 111.356837326252 -2.97272373347558 0.00317856205652383 CBR3 other 1 1 1 -0.784716060853993 -2.97272373347558 0.104005612869239 22.0059799412992 10.3232099937001 2.13169934107015 0.0337930623166658 0.422119504653696 42.7173433757285 0.0098816890587241 0.992121838789204 C2orf81 other 1 1 1 2.13169934107015 0.0098816890587241 0.49519090788809 381.748852947329 364.709149915768 1.04672134777945 0.296023054464726 -86.4013912196036 761.956980502262 -0.113394054297724 0.909789706127175 ACTC1 other 1 1 1 1.04672134777945 -0.113394054297724 7.87769142143601e-06 125.257190485103 44.7956226020022 2.79619264583018 0.00548646971851077 -217.029440747337 74.7349986353215 -2.9039866824158 0.00394311371965819 MORC3 other 0.0759251899198003 1 1 2.79619264583018 -2.9039866824158 1.37830219404947e-06 59.8028443862996 37.2708108089025 1.6045490583214 0.109591996836407 -261.076679613784 61.6148600717496 -4.23723561669643 2.97275134959297e-05 CHAF1B essential 0.0141303540933951 0.432148863690329 1 1.6045490583214 -4.23723561669643 0.0779621432133207 5.09637640472978 5.02914579601095 1.01336819639871 0.311659601935707 -13.0113062764849 8.31555439703666 -1.56469498667721 0.118655294191371 CLDN14 other 1 1 1 1.01336819639871 -1.56469498667721 0.256554391694574 43.5761378449592 97.4597610926369 0.447119276267663 0.655094279679748 -216.868306753571 161.37009825432 -1.34391878730709 0.17993572254972 SIM2 other 1 1 1 0.447119276267663 -1.34391878730709 7.0880252514639e-08 81.6028664540286 29.7496615499668 2.74298469974088 0.00643464812394142 -195.377928165303 49.2583375285289 -3.96639306091372 9.02600070567502e-05 HLCS other 0.000787479605437639 1 1 2.74298469974088 -3.96639306091372 0.135253325886549 -2.6317317421222 3.1825271976681 -0.826931422314481 0.408892118019172 -16.0789498032929 8.16149081921985 -1.9700996006058 0.0496889126783679 SCUBE1 other 1 1 1 -0.826931422314481 -1.9700996006058 0.00448258951376905 97.7589240028264 65.9941664473909 1.48132674849007 0.13950349990409 -453.630811082749 160.2769440063 -2.83029361393937 0.00494453768864389 ARHGAP27 other 1 1 1 1.48132674849007 -2.83029361393937 0.000595661152023165 95.8106050115592 46.2672419187336 2.07080865507061 0.0391781424337099 -210.668852651478 91.2209822077892 -2.3094341625439 0.0215558965572411 ADPGK other 1 1 1 2.07080865507061 -2.3094341625439 5.58274452962052e-13 1450.16411587011 187.383617248886 7.73901228485724 1.33257269239439e-13 -229.24727334077 1035.57382373618 -0.221372217109238 0.82494425874482 PTMS other 7.39211203167053e-09 1 1.89211996593079e-09 7.73901228485724 -0.221372217109238 0.522781394882748 77.4353034517883 68.0087788040166 1.13860746823489 0.255718596554018 54.6114960735692 135.997041829759 0.401563852704473 0.688273078256329 PLA2G4D other 1 1 1 1.13860746823489 0.401563852704473 0.00738715876300525 314.248796422231 106.362102399269 2.95451847353094 0.00336379946925133 -374.248638059608 361.75340977537 -1.03454073395465 0.301664624863256 ADIPOR1 other 1 1 1 2.95451847353094 -1.03454073395465 0.340546719223895 -231.289701223986 160.498298890914 -1.44107260215379 0.15054196045604 -179.887174071576 545.878706580863 -0.329536895106805 0.741965507424186 CYB5R1 other 1 1 1 -1.44107260215379 -0.329536895106805 1.43364941742434e-08 645.744095932834 105.246849734473 6.13551947219302 2.52909366919581e-09 260.721052090823 419.627439389742 0.621315547119573 0.534838546530581 PSMD4 essential 0.000165099066910586 1 3.3298047248632e-05 6.13551947219302 0.621315547119573 4.21107138364565e-06 374.6633081113 89.4997834514649 4.18619234218011 3.67033715262747e-05 -241.208711932201 174.320165005884 -1.38371089726802 0.167411416697464 ATP13A2 other 0.0415169527713625 1 0.395955972025451 4.18619234218011 -1.38371089726802 0.469177797948332 0.67446674932901 10.2049074086343 0.0660923928382095 0.947345539210681 52.0112755638566 42.2278084198789 1.23168304276412 0.218971849818058 M1AP other 1 1 1 0.0660923928382095 1.23168304276412 0.000246818699759132 619.16438919141 151.296865386329 4.09238081443661 5.42193992070436e-05 269.959519161626 603.232461303441 0.447521538509893 0.654804189308291 PSMB4 essential 1 1 0.576460652369287 4.09238081443661 0.447521538509893 0.00154845133413155 -11.770793258027 23.0821200028096 -0.509952866400237 0.610438226412881 180.819638588466 61.0770856683778 2.9605151688186 0.003302204640872 IRX6 other 1 1 1 -0.509952866400237 2.9605151688186 0.0547025109822522 394.510831871834 174.131644415102 2.26558953828854 0.02414447084435 -471.00221620172 592.247752686279 -0.795279026497575 0.427040693677542 BTG2 other 1 1 1 2.26558953828854 -0.795279026497575 0.00737204758544608 889.123392400292 282.970232244422 3.14210927894454 0.00183420860306423 594.200070629226 1170.92809148234 0.50746076975316 0.612181110533982 HK2 other 1 1 1 3.14210927894454 0.50746076975316 3.91298632570141e-06 1697.13357940885 333.808334636758 5.08415579633633 6.30701299429398e-07 850.126245038419 1874.57370046025 0.453503772526892 0.650494370818364 C1R other 0.0386876958022098 1 0.00758922873603395 5.08415579633633 0.453503772526892 5.06010869885013e-06 179.932927670772 70.1871783737886 2.56361534741462 0.0108153643664127 -452.579829013154 136.102155536422 -3.32529508610201 0.000985875900089762 ALDH4A1 other 0.0495738849226347 1 1 2.56361534741462 -3.32529508610201 0.0732335585995301 11.3726571946795 9.44060061742663 1.20465398924794 0.229229881856591 -25.4223203489377 19.1010810510749 -1.33093620622624 0.184160476974931 STARD9 other 1 1 1 1.20465398924794 -1.33093620622624 0.000110066210790791 51.933863892846 12.0330846642477 4.31592275313663 2.12512154825899e-05 14.5012612916236 48.2244211243335 0.300703688163225 0.763836958539353 THEM4 other 0.94359762510945 1 0.233147085059493 4.31592275313663 0.300703688163225 0.952091360990379 128.871145191237 570.117932469804 0.226042960327446 0.821313680799149 -549.041944300036 2552.90959539914 -0.215065173200618 0.829854801194274 TCHH other 1 1 1 0.226042960327446 -0.215065173200618 0.424001638294326 -7.21011268419535 8.64901204636885 -0.833634251581647 0.405110879963001 -34.3565066643218 34.8947138350202 -0.984576254923795 0.325578419796321 LCE2B other 1 1 1 -0.833634251581647 -0.984576254923795 5.05594935292467e-07 85.1846554565318 24.2117924411218 3.51831264305126 0.000497182216008089 -124.037690704335 49.0214930419388 -2.53027158104342 0.0118766568475136 UBR1 other 0.00534211608630021 1 1 3.51831264305126 -2.53027158104342 1.98487445090892e-22 502.911349824634 63.9043876940771 7.86974678847045 5.58130075311231e-14 -491.325937232308 168.465129692543 -2.91648448630885 0.0037909312591454 AMFR other 2.92491099085938e-18 1 7.96730682506783e-10 7.86974678847045 -2.91648448630885 4.89541363600018e-18 179.715959822011 21.9760600007071 8.17780620439824 6.86059508803655e-15 -235.708768554868 69.311217529689 -3.40073045829709 0.000757245999132522 MED8 essential 6.97988076220906e-14 1 9.8723963316846e-11 8.17780620439824 -3.40073045829709 0.763161320438092 -1.58664535137788 3.88468438744817 -0.408436102686875 0.683228423340248 -8.03433184106065 11.7836120544687 -0.681822500937969 0.495847472176611 RGL4 other 1 1 1 -0.408436102686875 -0.681822500937969 0.29950962920492 -929.202904742505 615.226055523595 -1.51034387506832 0.131942490863967 -755.116396709868 2236.93133104006 -0.337567982633949 0.735910096727887 SPRR2G other 1 1 1 -1.51034387506832 -0.337567982633949 0.348541660527531 45.3287335297905 31.4120264008874 1.44303754718957 0.149988045676564 -25.1342356806556 112.807723397817 -0.222805982813957 0.823828659858959 PGLYRP3 other 1 1 1 1.44303754718957 -0.222805982813957 0.347737269085294 1.07516082637117 3.08432270170295 0.34858895464393 0.727627871044941 -7.11334858880827 5.98899658084221 -1.18773629151212 0.235820921323915 ISL2 other 1 1 1 0.34858895464393 -1.18773629151212 3.51108069525452e-19 150.929332863142 21.6454474299184 6.97279801453891 1.78579651828368e-11 -178.42759080563 57.5070848907966 -3.10270623427455 0.00208853722349843 RSPRY1 other 5.06192503834844e-15 1 2.4588632260248e-07 6.97279801453891 -3.10270623427455 0.492447177404752 -12.0335598483768 11.8735029390155 -1.01348017600058 0.311598936222717 -24.1077252074764 30.1238066827239 -0.800288139589684 0.424139453606259 CCDC17 other 1 1 1 -1.01348017600058 -0.800288139589684 1.04095015333571e-05 280.321672797227 72.4701060498469 3.86810076701716 0.000132977961046485 -408.104147423411 183.861112944913 -2.21963274825647 0.0271465873418779 GPBP1L1 other 0.0992129591144262 1 1 3.86810076701716 -2.21963274825647 5.66471843920484e-09 152.417809489084 35.1946632244796 4.33070799731563 1.99121976361331e-05 -233.99680773055 94.8113603696349 -2.46802500057252 0.0141086684164017 NAE1 essential 6.65377827869e-05 1 0.218854964218738 4.33070799731563 -2.46802500057252 4.25349730438204e-05 71.1649397427894 22.941500364949 3.10201768021756 0.00209380670539423 -158.397505840207 58.2039963736823 -2.72141975996391 0.0068571321411511 TMEM69 other 0.382559547556121 1 1 3.10201768021756 -2.72141975996391 6.94380901816291e-08 -27.2864796976329 6.84432147805202 -3.9867326199001 8.30395352139383e-05 37.4202588017044 18.0162676741339 2.07702613429911 0.0385966286098033 ADGRG5 other 0.000771943248549171 1 0.868012261591297 -3.9867326199001 2.07702613429911 0.284559504572265 -21.5130034032899 18.4383437355907 -1.16675357135057 0.244181368825394 -51.3881026659104 42.5187481561978 -1.20859867456892 0.227712175440875 ACE other 1 1 1 -1.16675357135057 -1.20859867456892 0.889194358492752 0.628223636250528 2.04172014869568 0.307693312745068 0.758516502577038 2.54694288605339 5.39560037330155 0.472040683119555 0.637220481313396 TEPP other 1 1 1 0.307693312745068 0.472040683119555 0.00887166155341168 156.251030932633 91.6831766432028 1.70424975064624 0.089305129955654 -520.033604214957 232.666944101738 -2.23509878561676 0.0261005772378106 EFCAB14 other 1 1 1 1.70424975064624 -2.23509878561676 6.37771658725173e-06 871.066005039672 185.182983278218 4.70381235694311 3.81760572966372e-06 401.247600446879 341.613159839851 1.17456716431821 0.241049498222166 SPON2 other 0.0619276280622143 1 0.0440284468802117 4.70381235694311 1.17456716431821 0.000452672658534921 65.0176909357747 17.2848613540595 3.76153962730542 0.000200781462783348 -39.369517851599 69.7906860570146 -0.56410848031264 0.573075451661691 CHCHD6 other 1 1 1 3.76153962730542 -0.56410848031264 5.00915551998324e-27 621.149755967284 77.7823527492989 7.9857414183564 2.60039524793608e-14 -478.04096824109 143.48767274445 -3.33158214289583 0.000965597815414182 CTBP1 other 7.51774060439085e-23 1 3.72324591599487e-10 7.9857414183564 -3.33158214289583 5.15595051921431e-06 609.360252616516 155.603924307204 3.91609823036003 0.000110092472541711 -534.697649883006 416.538748566694 -1.28366845034921 0.200189634655589 TPPP3 other 0.0504715996325889 1 1 3.91609823036003 -1.28366845034921 0.0198179705932461 43.3575626576597 16.0166321565597 2.70703367810707 0.00715434702380146 16.7713480266249 42.8751906126417 0.39116672805368 0.695935135302345 ZDHHC1 other 1 1 1 2.70703367810707 0.39116672805368 2.88584107267015e-16 278.873558804077 85.0266989839402 3.27983518279065 0.00115349283343827 -1427.08161401907 227.609393189885 -6.26987135293014 1.17295009332832e-09 ATP6V0D1 other 4.03671449245101e-12 1.78956995739101e-05 1 3.27983518279065 -6.26987135293014 0.154744097607248 13.09916156796 9.53314735275569 1.37406473258524 0.17038324272905 -6.51448744526854 17.6314747996685 -0.369480574897287 0.71201392808199 ZFYVE28 other 1 1 1 1.37406473258524 -0.369480574897287 0.000216366294749325 -13.6837451973813 7.36063848901267 -1.85904323623654 0.0639416878000246 52.0499986596705 19.7038163305708 2.64162017075414 0.00865757240052373 CARMIL2 other 1 1 1 -1.85904323623654 2.64162017075414 0.0333973751212792 7.0537384519689 2.87256173097888 2.45555678609044 0.014599728806567 14.1483230292098 7.68960856180107 1.83992760041039 0.0667077968685376 C16orf86 other 1 1 1 2.45555678609044 1.83992760041039 0.47915009636245 99.2157776701351 228.45598467814 0.434288372046438 0.664371725886634 -384.151375463367 498.022080699635 -0.771354103263254 0.441066269886181 PIP other 1 1 1 0.434288372046438 -0.771354103263254 0.140503730869269 26.4363113266254 15.3489940083963 1.72234814295738 0.0859726882808382 -0.356915683870324 33.4600030000405 -0.0106669352023038 0.991495825465645 FAM131B other 1 1 1 1.72234814295738 -0.0106669352023038 3.1503604788052e-18 210.895050670717 91.7486893861538 2.29861649339858 0.0221709238842857 -1092.75277673151 169.68841925505 -6.43976048294166 4.38205666740697e-10 RGS12 other 4.50060498002111e-14 6.69709720479807e-06 1 2.29861649339858 -6.43976048294166 1.31713796205731e-11 148.526375218898 28.2629362822056 5.25516435149771 2.71159106267432e-07 -194.173244401116 75.6575270336233 -2.56647622535722 0.0107298139081692 PSKH1 other 1.68857086735748e-07 1 0.00331817398339456 5.25516435149771 -2.56647622535722 3.33295669256379e-11 836.87315970835 207.586699206356 4.03143921507437 6.9346677728112e-05 -1434.43584271167 451.962480012732 -3.17379407837407 0.00165078039894306 ZYX other 4.23152181687898e-07 1 0.730983329932028 4.03143921507437 -3.17379407837407 8.78847618167751e-07 397.830856887499 84.0804627886223 4.73154932421867 3.36119342172839e-06 -386.289255972331 160.597530001951 -2.40532501320313 0.0167307231170391 ABR other 0.00913649983847194 1 0.0388994307195965 4.73154932421867 -2.40532501320313 0.105666889497008 150.003032695106 91.6902699287972 1.63597547276927 0.102834041052845 -411.083626697601 384.206344205204 -1.06995533233059 0.285450860676826 LYPD5 other 1 1 1 1.63597547276927 -1.06995533233059 4.53515851473698e-06 141.392662474216 31.5422774239314 4.48263961964079 1.03246630963846e-05 -114.598318169753 90.9165057400706 -1.26047869126634 0.208426672480142 CCDC117 other 0.0445942136754088 1 0.115687849994989 4.48263961964079 -1.26047869126634 5.48928734407828e-23 28.9917297110753 2.73854311668463 10.5865522198437 1.20747742893721e-22 -13.3747981018042 11.5330485284036 -1.15969321284521 0.247040997102358 ZNF230 other 8.11646026695414e-19 1 1.8096464227482e-18 10.5865522198437 -1.15969321284521 1.69966074897337e-07 90.8280840462675 17.7521571639507 5.11645335310078 5.4874905873163e-07 -81.2174303322173 55.9114903132573 -1.45260714527868 0.147350840422848 CCDC107 other 0.00185144045385669 1 0.00662292657685544 5.11645335310078 -1.45260714527868 2.03344128960916e-35 21.9791674417589 1.54583409688155 14.2183223193861 7.09362390180163e-36 0.815766853928976 6.51009638941865 0.125307953236284 0.900358687838101 ZNF222 other 3.09408426626931e-31 1 1.08241607117591e-31 14.2183223193861 0.125307953236284 5.98084619808159e-13 88.8014302287096 11.4326072175433 7.76738223739937 1.19996959160998e-13 105.256965575747 36.6952525845131 2.86840825889749 0.00441032409313854 NPR2 other 7.91385568930156e-09 1 1.7053967835961e-09 7.76738223739937 2.86840825889749 1.95048989158636e-16 5.48548385648323 0.626928086730966 8.74978162979835 1.25985024070409e-16 -1.75150710027364 2.64023305093726 -0.663391097104808 0.507559216550933 ZNF221 other 2.7330264360908e-12 1 1.83610574080213e-12 8.74978162979835 -0.663391097104808 6.8458135267505e-40 60.1031060909579 3.90269962178984 15.4003925271076 2.2656127472079e-40 4.27039068649367 16.4354948074372 0.259827327167618 0.795165110233771 ZNF235 other 1.04542418367007e-35 1 3.46344220665672e-36 15.4003925271076 0.259827327167618 0.00678425911401215 15.0230838517772 39.3383835301505 0.381893776602766 0.702805224169744 -372.57542051572 124.069515998578 -3.00295699162711 0.00289426363648191 GNE other 1 1 1 0.381893776602766 -3.00295699162711 2.05902821667496e-07 520.279056636615 116.590125400423 4.46246244996943 1.12380361636373e-05 -616.050233213929 264.042623930356 -2.33314691409981 0.0202597072747786 ARHGAP35 other 0.00223301610098399 1 0.125596292164811 4.46246244996943 -2.33314691409981 0.725885473849593 -1.8659070256602 9.5994222814401 -0.194377012590415 0.846004027383753 -17.5914174927519 21.9658227062665 -0.800854023452231 0.423810358407665 PTGIR other 1 1 1 -0.194377012590415 -0.800854023452231 1.002140022914e-10 213.537791217422 41.4794195313527 5.14804193573676 4.612942938136e-07 -262.341799955765 87.552459516253 -2.99639554851186 0.00294614767221056 DFFA other 1.25347674066084e-06 1 0.00558350613231981 5.14804193573676 -2.99639554851186 0.270640392163271 -1.93402093129075 27.2151431471536 -0.0710641469285467 0.943391233311679 -96.5993730724509 60.6509783675262 -1.59270923029615 0.112215799388912 CCDC28B other 1 1 1 -0.0710641469285467 -1.59270923029615 0.0137687723918422 1.40630213863189 6.36064540300788 0.221094252159831 0.825160495320701 -39.8753539107135 14.1751731620667 -2.81304174945964 0.00521182556538627 IQCC other 1 1 1 0.221094252159831 -2.81304174945964 1.25957209167694e-06 41.8935234339453 9.85839889774896 4.24952610139474 2.81555507112994e-05 -47.5916439152638 21.9701779649964 -2.16619291801315 0.031036763790919 TMEM234 other 0.0129509202466223 1 0.30616345843467 4.24952610139474 -2.16619291801315 0.00171522496070538 134.352069202042 62.2514923788436 2.15821443097969 0.0316616970290489 -326.176761468945 139.843651324469 -2.33243882278316 0.020303294937034 BSDC1 other 1 1 1 2.15821443097969 -2.33243882278316 0.099757510482289 5.0511965551406 10.0078895905405 0.504721450955555 0.614105161402483 -43.374432653842 22.4820284448148 -1.92929355819962 0.0545867720463848 ZBTB8A other 1 1 1 0.504721450955555 -1.92929355819962 1.05076138871761e-05 151.751681231937 51.8274572628472 2.92801710225366 0.00365987171610178 -347.677098773192 117.898724520368 -2.94894707459816 0.0034271742524734 ATAD3B other 0.100074514661465 1 1 2.92801710225366 -2.94894707459816 8.6775209919515e-10 544.340318503626 111.118098999699 4.8987547789591 1.54280725062436e-06 -758.120177938613 251.136230799169 -3.01876067633138 0.00274475945674416 SSU72 essential 1.05223619548404e-05 1 0.0182128395936205 4.8987547789591 -3.01876067633138 2.62206866221444e-14 207.177406637156 37.9977156432079 5.45236478378113 1.00558549027609e-07 -386.853140171338 86.1926736962198 -4.48823691831136 1.00834048589379e-05 UBE2J2 other 3.5618180707521e-10 0.148437802928425 0.00125205449394275 5.45236478378113 -4.48823691831136 0.0987967473127886 74.2214297955365 34.3940893651562 2.15797048753174 0.0316808282789082 33.7719327155041 81.097280016612 0.416437304784899 0.677371853051501 ZNF362 other 1 1 1 2.15797048753174 0.416437304784899 0.504112470143822 48.4290613924773 50.6714778942465 0.95574598186283 0.339928859918658 -50.7231788487563 113.869500892825 -0.445450084974884 0.656298571121788 FNDC5 other 1 1 1 0.95574598186283 -0.445450084974884 0.334677111710218 15.0655750878399 14.4579839056384 1.0420246132633 0.298191810405455 -24.3031980728805 33.9098712403098 -0.716699804037901 0.47408538185024 CPAMD8 other 1 1 1 1.0420246132633 -0.716699804037901 0.000158415677434839 146.292529968724 55.6380165406452 2.62936278222378 0.0089689282592629 -314.393982415501 130.55042679807 -2.40821872533434 0.0165975144869013 NR2F6 other 1 1 1 2.62936278222378 -2.40821872533434 2.01904545714446e-08 51.3057049988791 8.58644927897624 5.97519455737078 6.13923572154705e-09 9.717963087499 20.147458298256 0.4823418886709 0.629893888822596 ANKLE1 other 0.000231120133479327 1 7.99144313873779e-05 5.97519455737078 0.4823418886709 6.43493773019621e-13 80.7016645073516 10.8415525420476 7.44373688125942 9.12483237416724e-13 -45.1171237922654 42.6819401515467 -1.05705419275863 0.291284187172256 CCDC58 other 8.51149213573052e-09 1 1.28140021030431e-08 7.44373688125942 -1.05705419275863 0.00015360454880902 70.1209534195357 17.1107525488922 4.09806367190295 5.28559164965869e-05 -23.5043984005816 68.0597612886753 -0.345349409923548 0.730058606338634 KALRN other 1 1 0.562704087022665 4.09806367190295 -0.345349409923548 0.0594531985769785 36.2644235363172 15.6891932775847 2.31142690989272 0.0214482551366707 4.69128718074719 35.6870110937151 0.131456432942163 0.895497377353497 CILP2 other 1 1 1 2.31142690989272 0.131456432942163 1.63555685399302e-05 18.2525934233731 4.17879806799078 4.3679051072571 1.72622914711712e-05 -18.9295308011317 21.0489448682656 -0.899310199138332 0.369203947244178 FAM86C2P other 0.153251677219146 1 0.190541173258787 4.3679051072571 -0.899310199138332 0.171468980693424 -3.47999011476119 56.5834099739464 -0.0615019511260198 0.950997975161594 -158.105558834965 90.5095532647917 -1.74683835166457 0.081627795375425 ABCG1 other 1 1 1 -0.0615019511260198 -1.74683835166457 0.248649997740813 764.631481395673 468.7389021622 1.63125244751093 0.103823879557318 745.372934727204 749.78423272942 0.994116576730139 0.320919580150449 TFF3 other 1 1 1 1.63125244751093 0.994116576730139 0.51104093159983 -20.6158812535719 17.9166753329429 -1.15065328083866 0.250736695623492 -9.4715581137192 28.6591119397301 -0.3304902864275 0.741246482961163 TFF1 other 1 1 1 -1.15065328083866 -0.3304902864275 0.0152438631018865 -16.2869653862193 20.4160005503118 -0.797754944514368 0.42560614315109 -94.1831059124066 32.6569764903405 -2.88401181108315 0.00419341360151437 TMPRSS3 other 1 1 1 -0.797754944514368 -2.88401181108315 0.00578425255521949 -11.4570069351127 5.80787579318825 -1.9726673474233 0.0493966933293184 -29.2037631733227 9.29014783133268 -3.14351974839709 0.00182616102211393 UBASH3A other 1 1 1 -1.9726673474233 -3.14351974839709 0.16069840584475 -58.1541324930882 46.9174759043117 -1.23949831853047 0.216072108191261 62.9243970642451 75.0481419618605 0.838453763401941 0.402403718996888 RSPH1 other 1 1 1 -1.23949831853047 0.838453763401941 0.00127392820793609 1.03733222124411 31.6167986453006 0.0328095273933844 0.973846999338561 -170.047635500631 50.573521856789 -3.36238468782462 0.000866751278276555 SLC37A1 other 1 1 1 0.0328095273933844 -3.36238468782462 0.930363162160484 7.12289942374329 20.1255803892269 0.353922683767973 0.723630636320951 8.69633535137003 31.8429764411864 0.273100580513636 0.784952616530244 PDE9A other 1 1 1 0.353922683767973 0.273100580513636 8.0357413571664e-07 82.9869245443927 26.0223757045182 3.189060272079 0.00156904921469009 -109.245708708356 41.1729689518039 -2.65333570761526 0.00836908850873129 WDR4 essential 0.00837324249416739 1 1 3.189060272079 -2.65333570761526 3.82764367460707e-09 137.026567452591 33.299435256925 4.1149817225232 4.93420209425102e-05 -145.802680512413 52.6868349574988 -2.76734559268988 0.00598141461706248 NDUFV3 other 4.52810246706016e-05 1 0.526627389519411 4.1149817225232 -2.76734559268988 3.87681543302855e-07 34.2685231679444 16.5237493429713 2.07389512250869 0.0388935794257077 -103.34664737852 26.5088393282588 -3.89857307967274 0.000118049302848544 PKNOX1 other 0.00413229757006513 1 1 2.07389512250869 -3.89857307967274 0.0197700656369065 31.6317855691958 52.2275488119517 0.605653267073433 0.54517840012604 -191.680370091601 84.1210723064678 -2.27862490141919 0.0233542196905048 CBS other 1 1 1 0.605653267073433 -2.27862490141919 3.14561939073182e-12 150.681666059145 39.1947135344377 3.84443850895226 0.000146021049342451 -281.262953762549 63.1295438185914 -4.45533005229349 1.16299098098781e-05 U2AF1 essential 4.09528188479376e-08 0.170889894746349 1 3.84443850895226 -4.45533005229349 4.81974474242271e-06 8.46497275316762 2.90394051022801 2.91499523607768 0.00381102016482577 -12.16748027279 4.67982323614757 -2.5999871488322 0.00976053243609034 HSF2BP other 0.0473057946468789 1 1 2.91499523607768 -2.5999871488322 2.95832427443076e-13 313.661891798216 58.4259258919181 5.36853951409273 1.53400318434492e-07 -301.771823819421 93.9331979972719 -3.21262163168538 0.00145001683652602 RRP1B other 3.94048793354178e-09 1 0.00189664153712405 5.36853951409273 -3.21262163168538 0.409373611015399 1066.61049785406 2659.48774264886 0.401058625219198 0.688646309460528 -4308.18299251372 4275.74205950425 -1.00758720534541 0.314418733064946 CSTB other 1 1 1 0.401058625219198 -1.00758720534541 4.95738839814519e-06 286.843435388583 94.3248766429999 3.04101574894422 0.00255389761128859 -376.411240991267 153.713571704955 -2.44878338858567 0.0148735593225986 RRP1 essential 0.0486270227974062 1 1 3.04101574894422 -2.44878338858567 1.13931818188233e-09 302.498426953505 99.4767404034498 3.04089604993747 0.00255488402127388 -675.039706680767 162.10914461997 -4.16410627705953 4.03015087839913e-05 AGPAT3 other 1.3729923409864e-05 0.583122530595571 1 3.04089604993747 -4.16410627705953 5.81795223063559e-09 125.221451925406 42.1270895178741 2.97246862668441 0.00317967680498712 -268.064435160516 68.5334187957954 -3.91144116068761 0.000112206406080813 TRAPPC10 other 6.83085771398925e-05 1 1 2.97246862668441 -3.91144116068761 1.64781443828578e-05 109.572580193351 31.6056661372847 3.46686507784405 0.000598757126704354 -86.8782399807171 52.0571357287435 -1.66890165516246 0.0961179620719947 C21orf2 other 0.154317822145463 1 1 3.46686507784405 -1.66890165516246 0.00035982171761384 68.3809440755944 20.2758799132741 3.3725265866675 0.000836814836840073 -24.3503540574168 33.6047886821336 -0.724609646790099 0.469224336895033 LRRC3 other 1 1 1 3.3725265866675 -0.724609646790099 0.475148603833605 160.95722449437 212.993331203351 0.755691380500074 0.450390145292426 -207.796022186118 356.078081506145 -0.583568697368789 0.559921606720832 ITGB2 other 1 1 1 0.755691380500074 -0.583568697368789 0.00370479851481489 47.4452443647637 23.5274381583436 2.01659203375435 0.0445731295803837 -66.5470801352086 39.3327105353318 -1.69190170800537 0.0916381833173048 FAM207A other 1 1 1 2.01659203375435 -1.69190170800537 1.99729935981774e-08 419.080423387233 74.9393691395597 5.59225982549679 4.81027474512248e-08 -304.854306433127 156.753886128679 -1.94479584501575 0.0526753515170121 RALGDS other 0.00022871074969273 1 0.000606479439865043 5.59225982549679 -1.94479584501575 9.00859374606445e-09 116.267903772291 19.4241805333558 5.98573018679642 5.79240181575981e-09 20.246976273691 32.6006422994476 0.621060655422548 0.535003224307268 SPATC1L other 0.00010481498823546 1 7.54749956593503e-05 5.98573018679642 0.621060655422548 7.78771032233453e-06 192.677123011998 103.647495238785 1.85896555018627 0.0639527336765662 -605.909576425384 174.57832522135 -3.47070333993149 0.000590573373240866 LSS other 0.0750891029279496 1 1 1.85896555018627 -3.47070333993149 1.31013309379275e-10 590.89145002009 90.863831617929 6.50304350475461 3.02573078666274e-10 -352.436817743626 190.905092443708 -1.84613628286291 0.0657958216637343 VAV2 other 1.63111570177197e-06 1 4.07293621192671e-06 6.50304350475461 -1.84613628286291 2.5858724699709e-18 390.70390568114 63.5666016820663 6.14637081962126 2.37168758456541e-09 -465.366805408378 107.124929949983 -4.34415038241479 1.88289188370881e-05 MCM3AP essential 3.69883198104638e-14 0.275165819885206 3.12564706769875e-05 6.14637081962126 -4.34415038241479 0.00028738236176994 20.2632445411893 15.4909735186596 1.30806785750303 0.191795037714896 -79.4057423510346 26.1059960597458 -3.0416668327578 0.00254853831592318 C21orf58 other 1 1 1 1.30806785750303 -3.0416668327578 7.8306459085753e-06 171.277412834765 63.4758303558388 2.69830913395858 0.00734376891410992 -297.181404749873 107.08604779635 -2.77516456032661 0.0058459699839478 PCNT other 0.0754795959127573 1 1 2.69830913395858 -2.77516456032661 2.90432628410885e-09 112.408494577112 35.5113096877538 3.16542801618709 0.00170091021613901 -240.38991934777 59.8858118850661 -4.01413810351491 7.47250622662073e-05 DIP2A other 3.45179178866336e-05 1 1 3.16542801618709 -4.01413810351491 0.222278240808641 -39.8914455718761 32.7385035027185 -1.21848714216774 0.22395945677506 -88.7720639665798 55.2402644479533 -1.60701736050195 0.109062070833797 S100B other 1 1 1 -1.21848714216774 -1.60701736050195 1.11597278889028e-14 196.096467274137 64.7442208903838 3.02878719640694 0.00266044927458371 -673.869556469001 109.244085734234 -6.16847632473553 2.13560424037159e-09 PRMT2 other 1.52687396975968e-10 3.25615578529457e-05 1 3.02878719640694 -6.16847632473553 5.94201063433565e-08 33.7453130151456 5.74569781873627 5.87314440817002 1.07113724747842e-08 16.385358439035 12.0501546830007 1.35976332836208 0.174862115852736 ADAMTS13 other 0.000663484907429918 1 0.000138305241394414 5.87314440817002 1.35976332836208 0.000287413061886637 103.133152787634 25.213673201375 4.09036604718149 5.45505151557705e-05 20.7632258582799 52.8793319433608 0.392652953341383 0.694837243360994 CACFD1 other 1 1 0.579708324560373 4.09036604718149 0.392652953341383 0.0789124846615259 27.055719027928 16.004916697543 1.69046297079955 0.0919131922683509 -44.3628881651759 33.566283500853 -1.32165028529442 0.187228714816234 SLC2A6 other 1 1 1 1.69046297079955 -1.32165028529442 0.0170753565125253 27.3134937601342 10.8464065350362 2.51820671407675 0.0122844865983499 -30.75280252536 34.5319200896121 -0.890561615037763 0.373835559001769 ZNF761 other 1 1 1 2.51820671407675 -0.890561615037763 0.622215171590401 -4.95167253727274 6.02471482552176 -0.821893264772729 0.411753441507497 5.41366237196363 12.5293309891486 0.432079125106702 0.665976735369473 C9orf116 other 1 1 1 -0.821893264772729 0.432079125106702 0.196161522610664 -9.28103006751313 6.4544146646095 -1.43793520400887 0.151435775491532 12.5661342024677 13.4229585990576 0.936167247312375 0.349897475724253 LCN1 other 1 1 1 -1.43793520400887 0.936167247312375 0.0113147249719399 8.91532660367399 10.6732613805056 0.835295443992175 0.404178505571161 -59.4877340219497 24.2391367581638 -2.45420183958961 0.0146555001863959 ZNF714 other 1 1 1 0.835295443992175 -2.45420183958961 2.93155322571031e-11 152.901073601336 22.3298558059263 6.84738293566393 3.87190770587913e-11 147.081360122243 46.5560084659283 3.15923475763355 0.0017333381571946 GPSM1 other 3.72922885842609e-07 1 5.30025445857795e-07 6.84738293566393 3.15923475763355 5.59103117952969e-17 92.889825593988 13.1036327024253 7.08886060098399 8.68792161780498e-12 -147.080841469532 39.024635314981 -3.76892289402306 0.000195181274131084 C19orf47 other 7.87720382883937e-13 1 1.20319026484981e-07 7.08886060098399 -3.76892289402306 7.84483178249637e-05 60.0279764142451 14.8926140247626 4.0307212900592 6.95485305096687e-05 -37.3837659968225 29.1727830588225 -1.28146039140125 0.200959783609158 CFAP157 other 0.683677089844559 1 0.732948479684414 4.0307212900592 -1.28146039140125 2.35670101995113e-10 74.4702012859266 11.8493535613574 6.28474801602557 1.07354130125866e-09 -47.7360580991527 23.200864415145 -2.0575120497662 0.0404468840340086 TOR2A other 2.91712452249551e-06 1 1.4277025765439e-05 6.28474801602557 -2.0575120497662 6.3156789601346e-08 180.23261173178 32.9585406622254 5.46846456519082 9.15978752004148e-08 -100.976367473213 64.5323501628841 -1.56474027706014 0.118632164967578 ST6GALNAC6 other 0.000704071890475806 1 0.00114259189524997 5.46846456519082 -1.56474027706014 5.46935303547629e-12 323.267577104027 51.52295502281 6.27424372225761 1.14008403054787e-09 -350.488186095138 151.125783799638 -2.31918192437509 0.0210145327207512 SHKBP1 other 7.08335911624535e-08 1 1.51494365979201e-05 6.27424372225761 -2.31918192437509 0.0146657878703112 72.7025938304475 29.6926145210165 2.44850765091732 0.0148813364960199 -70.8959053229853 77.8221728963623 -0.910998789733089 0.362981732963243 RDH13 other 1 1 1 2.44850765091732 -0.910998789733089 2.8801923528029e-11 271.925816156944 42.3341553972231 6.42331974278106 4.82257025650137e-10 -209.403290736127 82.6934130813945 -2.53228501440632 0.0118100318807554 ZER1 other 3.66418071123585e-07 1 6.46754897099398e-06 6.42331974278106 -2.53228501440632 1.36917845635522e-17 393.649688841054 50.3221824667028 7.82258776438253 7.5908516049378e-14 -410.40248013882 98.2968239907138 -4.17513469384922 3.84351072477018e-05 ZDHHC12 other 1.94423340802442e-13 0.556655658268465 1.08177226221969e-09 7.82258776438253 -4.17513469384922 0.000171080724318124 51.3708405290401 17.0953941304015 3.00495210213873 0.00286609002503804 -86.0655100390751 33.3932843433383 -2.57732989526214 0.01040401477555 PKN3 other 1 1 1 3.00495210213873 -2.57732989526214 0.0593558904145776 12.195569785677 5.74096936995882 2.12430497356311 0.034411105025032 -8.27710402509149 16.8392611685537 -0.491536056258126 0.623384330883004 SPTBN4 other 1 1 1 2.12430497356311 -0.491536056258126 0.00180019912601692 18.5627119288616 5.78746021091024 3.20740208180924 0.00147486121232253 -11.1472743175495 15.1036087792626 -0.738053698322404 0.46102271650184 BRSK1 other 1 1 1 3.20740208180924 -0.738053698322404 0.311734212621984 10.5294529620921 25.3228829559822 0.415807828057928 0.677829333534318 -86.9857758101626 66.0854508527252 -1.31626212256635 0.189028117929157 COX6B2 other 1 1 1 0.415807828057928 -1.31626212256635 0.0838163799898433 -1.44601773153577 13.7924132291175 -0.104841531899801 0.916567649818687 62.9624388470556 28.4750897196953 2.21114101717848 0.0277372007147413 PLPP7 other 1 1 1 -0.104841531899801 2.21114101717848 3.12468006769287e-11 127.001380993478 17.904603436369 7.09322501583614 8.45432771198676e-12 -23.4566561579773 37.0123489355119 -0.633752161983742 0.52669529864435 MED27 other 3.9708434300241e-07 1 1.17100893138729e-07 7.09322501583614 -0.633752161983742 1.21971886054803e-05 114.055929783268 39.2785085766387 2.90377445367423 0.00394571707251238 -284.918998103028 97.318513163783 -2.92769575736861 0.00366195714777776 DEDD2 other 0.115580559225531 1 1 2.90377445367423 -2.92769575736861 3.06622095207615e-23 290.777864520821 40.1013971952921 7.25106566997516 3.13061411768855e-12 -135.058076446106 74.7525633048342 -1.80673505328977 0.0717428345474175 SIK3 other 4.53892687535833e-19 1 4.36438914146961e-08 7.25106566997516 -1.80673505328977 6.41538924170783e-16 145.502603713468 49.8019279636234 2.92162592218813 0.0037305423176984 -433.148888857005 94.1656113365369 -4.59986275997276 6.10602270874365e-06 MPZL3 other 8.93407105800233e-12 0.0903874541575323 1 2.92162592218813 -4.59986275997276 0.000782603895569575 -46.6589040474542 21.058529263439 -2.21567724240181 0.0274192968681473 40.0023498450408 39.817520385727 1.00464191284448 0.315830750011847 JAML other 1 1 1 -2.21567724240181 1.00464191284448 1.13441251546495e-11 37.9442570922962 5.22594464070657 7.26074608535577 3.06750864889318e-12 -7.53721264377832 16.6062129212233 -0.453879080048739 0.650230408063434 NEK8 other 1.45681255236009e-07 1 4.27733406001665e-08 7.26074608535577 -0.453879080048739 1.90833453758674e-07 49.250194457474 8.86793959361729 5.55373589744814 5.97757272314199e-08 -16.0003085879809 28.1791911680573 -0.567805814317273 0.570573893658243 TLCD1 other 0.00207359630854176 1 0.000750783134026634 5.55373589744814 -0.567805814317273 0.00312621750275626 595.702317712634 205.382022104001 2.90045989230246 0.00398409732485601 173.635376399477 379.4659664648 0.457578259302429 0.647565985252402 PCSK7 other 1 1 1 2.90045989230246 0.457578259302429 1.26094628315242e-10 344.450993720317 86.7591193131462 3.97019928795109 8.88398489636445e-05 -528.726496207434 159.021426395539 -3.32487582454654 0.000987977141978625 SAFB other 1.57113906880792e-06 1 0.926155425445994 3.97019928795109 -3.32487582454654 3.55758043002391e-05 -30.4403436966576 11.4772007369889 -2.6522446016435 0.00839558637564094 26.5335511309989 21.7011201779201 1.22268117560105 0.222352695302378 CD3G other 0.322387938568767 1 1 -2.6522446016435 1.22268117560105 0.177865137448888 133.464571883554 80.0736637377265 1.6667723899921 0.0965380789286086 -247.805185531571 287.562718657339 -0.861743089259275 0.389474188803096 S100A1 other 1 1 1 1.6667723899921 -0.861743089259275 0.00520219543596254 142.107892133144 43.4598216098416 3.26986827992325 0.0011931509619116 -7.6547444517466 156.0740931678 -0.0490455801881018 0.96091356899892 CHTOP other 1 1 1 3.26986827992325 -0.0490455801881018 2.67712369118041e-23 304.038803222116 46.7431150835344 6.50446173043389 3.01233052189393e-10 -248.572552680591 88.382000207505 -2.81247937472548 0.00522072325337469 CXCR5 other 3.96401704953084e-19 1 4.0551993485736e-06 6.50446173043389 -2.81247937472548 0.0274418496939726 176.158226463362 87.6694879276307 2.00934476324051 0.0453425615570168 -582.594887071256 310.131224245091 -1.8785431505305 0.0612187120531196 ZBTB7B other 1 1 1 2.00934476324051 -1.8785431505305 5.5540797240643e-12 270.509605675048 36.1048467418824 7.49233496568899 6.70630152871854e-13 10.1727675115274 127.721064488075 0.0796483144914377 0.936566909527794 FLAD1 other 7.19142242671845e-08 1 9.42973057953114e-09 7.49233496568899 0.0796483144914377 0.0120163853799391 503.700229728365 199.445185603342 2.52550708709574 0.0120371750789322 -1206.24156821165 705.538278403237 -1.70967558406838 0.0882983193234651 SHC1 other 1 1 1 2.52550708709574 -1.70967558406838 2.98021772179714e-16 132.513783984516 27.4062760718091 4.8351619766694 2.07247518600225e-06 -143.65534707262 51.7016470091673 -2.77854488943357 0.00578383387781343 VPS11 other 4.16753646216112e-12 1 0.0242728293784583 4.8351619766694 -2.77854488943357 2.15352566670392e-18 218.96239967762 79.1864192883306 2.7651509140771 0.00602084232245285 -805.820367145174 149.384333983866 -5.3942762648204 1.34293151994491e-07 NLRX1 other 3.08126452391997e-14 0.00202796088826881 1 2.7651509140771 -5.3942762648204 0.000309520279020295 1197.99283440713 295.801627203206 4.04998730309265 6.43206477275405e-05 -610.119092572202 1047.16905268963 -0.582636672660567 0.560548227538422 ADAR other 1 1 0.679869246480103 4.04998730309265 -0.582636672660567 0.120581661704765 74.7869472248622 42.7900678898113 1.74776416381124 0.0814640045794132 -176.96594145564 151.481367024112 -1.16823570404848 0.243581320574194 IL6R other 1 1 1 1.74776416381124 -1.16823570404848 1.73066125090189e-12 343.922840914536 44.7820599605101 7.67992453267706 1.95481649570073e-13 -19.1550921758975 158.533229684103 -0.12082698506847 0.903903906614623 UBE2Q1 other 2.26768543705675e-08 1 2.7695840111088e-09 7.67992453267706 -0.12082698506847 0.404062884387089 14.3847776852135 10.6812841595953 1.34672736632433 0.179021077706684 0.249165874753532 37.8128758812684 0.00658944523383799 0.99474652742304 CHRNB2 other 1 1 1 1.34672736632433 0.00658944523383799 3.40983047895132e-10 194.691501621431 28.5660740844187 6.81547982568684 4.67939112375743e-11 -64.2579545355219 101.61747258292 -0.632351434278073 0.527608810917214 CRTC2 other 4.19647837044538e-06 1 6.39345209238977e-07 6.81547982568684 -0.632351434278073 4.93366223248857e-08 121.915904665664 32.7551561290824 3.72203704922716 0.000233412097582867 -94.7330860424418 46.9391205483573 -2.01821178018976 0.0444032635053661 ANO10 other 0.000552964863017319 1 1 3.72203704922716 -2.01821178018976 0.582226593099555 150.284609961039 148.018902283182 1.01530688069502 0.310729004678452 -129.665971899169 512.185885683225 -0.253161938904667 0.800306145540915 FDPS essential 1 1 1 1.01530688069502 -0.253161938904667 1.73166704358698e-08 254.70144501948 41.4563119625048 6.14385199652695 2.39791094176442e-09 -59.838889050416 143.450177863454 -0.417140570626375 0.676856173541056 RUSC1 other 0.0001988992766264 1 3.15972724796298e-05 6.14385199652695 -0.417140570626375 2.78452652823312e-05 100.389754853608 22.0850016077801 4.54560776750149 7.7941748206356e-06 63.0745991328876 77.4193460968558 0.814713664127023 0.415845939444116 GBAP1 other 0.255368927904259 1 0.0881832939206712 4.54560776750149 0.814713664127023 6.71505743668302e-14 263.537441715629 32.3022983629715 8.15847339264643 7.97065760489011e-15 38.1298154807654 111.695227676768 0.341373720917678 0.733047712197455 FAM189B other 9.05659796485439e-10 1 1.14641968331134e-10 8.15847339264643 0.341373720917678 0.350639389135973 8.94057801297981 7.98168132384883 1.12013718040407 0.263495299758898 -26.266161300127 27.7928036196585 -0.945070589479803 0.345335869621559 PAQR6 other 1 1 1 1.12013718040407 -0.945070589479803 0.000241629458140989 130.133263011103 31.5974909602309 4.11846824087679 4.86030712998403e-05 -50.3375842525883 110.024796217768 -0.457511270031867 0.647614071368297 PMF1 essential 1 1 0.519178007624894 4.11846824087679 -0.457511270031867 1.46557609092386e-05 105.501730642018 22.0864708314848 4.77675819948666 2.71738985002562e-06 -45.3733502583449 76.9067219755614 -0.589978991339185 0.555621092941073 SLC25A44 other 0.137910710155935 1 0.031632432442468 4.77675819948666 -0.589978991339185 1.30432630344037e-05 3134.52938962688 649.789710307716 4.8239135521898 2.18160251565211e-06 178.93717125846 2262.61574221166 0.0790842067966668 0.937015076207611 LMNA other 0.123284922201184 1 0.0255160230230671 4.8239135521898 0.0790842067966668 0.000103385939815852 -67.0413043002865 29.4805855168882 -2.27408320170172 0.0236228355225474 -184.346920218454 42.4163653870407 -4.34612722085748 1.86360848217141e-05 CCR5 other 0.889015696476515 0.272440924008639 1 -2.27408320170172 -4.34612722085748 2.83833100671133e-10 -75.4142583467369 198.300065522731 -0.380303749007547 0.703972259525516 -1707.65248686138 283.828708753688 -6.01648964391165 4.87144023806412e-09 NBEAL2 other 3.5042034608858e-06 7.41579347440501e-05 1 -0.380303749007547 -6.01648964391165 2.61697873813536e-09 77.7802546791921 58.9746781603722 1.31887544121362 0.188153794071893 -395.826083615912 84.4109995995138 -4.68927136858822 4.06562709711405e-06 CCDC12 other 3.11603658349778e-05 0.0603826936463378 1 1.31887544121362 -4.68927136858822 0.256219467892052 16.6895546699722 13.8737438176058 1.2029596977849 0.229881185934707 31.7651993074693 19.857617207288 1.59964808344735 0.110663483343297 PTH1R other 1 1 1 1.2029596977849 1.59964808344735 3.61644009619509e-21 382.449657626088 36.6247272310848 10.4423892419188 3.68459430876585e-22 52.18057497363 127.530004050106 0.409163124884152 0.682693671315389 UBQLN4 other 5.28976692870456e-17 1 5.51399538306809e-18 10.4423892419188 0.409163124884152 0.394963306140081 118.113673383668 87.3016877767977 1.35293688348439 0.177030881074313 108.724625818283 124.955709159187 0.870105308111797 0.384895070531039 MYL3 other 1 1 1 1.35293688348439 0.870105308111797 2.06308136247504e-08 68.8833234085601 11.555650452667 5.96100788014597 6.61966729099913e-09 -1.95069139049788 50.0172375010927 -0.0390003824272636 0.968914403415064 PPP1R35 other 0.00023603713868077 1 8.60689141175707e-05 5.96100788014597 -0.0390003824272636 0.000536854845124976 140.133265036811 35.6936555308347 3.925999255407 0.000105795811801064 -2.21416168912317 119.653647748892 -0.0185047571117085 0.985247714929721 GPATCH4 other 1 1 1 3.925999255407 -0.0185047571117085 0.0980819030220133 -11.7982115416083 5.74228404071495 -2.05461998360836 0.0407299769269306 14.657706396271 19.8137302018347 0.739775208754672 0.45998046483275 FCRL3 other 1 1 1 -2.05461998360836 0.739775208754672 0.8290722145749 -3.20979529957432 348.035245332249 -0.00922261564776325 0.992647304691252 -900.130107270026 1498.07197234786 -0.600859053426714 0.548361886624848 AZGP1 other 1 1 1 -0.00922261564776325 -0.600859053426714 5.96600377098581e-06 122.042695449437 24.4385217585214 4.99386569512463 9.74747900899187e-07 71.4627870142634 37.2121407432888 1.92041590692822 0.0556939252727499 FGFR4 other 0.0580969447218598 1 0.0116287424577273 4.99386569512463 1.92041590692822 1.89928548727064e-13 372.107560676181 55.2815877797587 6.73113012163568 7.93285062506539e-11 -545.863779276063 183.383428612138 -2.97662544215259 0.00313949607607496 NACC1 other 2.53972455357829e-09 1 1.0796609700714e-06 6.73113012163568 -2.97662544215259 0.609547123598645 10.4661029887603 21.8776520172714 0.478392424401749 0.632697597978507 -21.8497986184506 33.3127459198929 -0.655899056505062 0.512360379700245 HK3 other 1 1 1 0.478392424401749 -0.655899056505062 4.50319180825665e-08 371.231072001055 65.2917424104085 5.68572775509013 2.93632443269089e-08 -412.967877454225 322.312521171976 -1.28126538786831 0.201028160825484 LY6K other 0.000505798503903387 1 0.000373294925127993 5.68572775509013 -1.28126538786831 0.000162988388394231 589.967248035829 255.200774398873 2.31177687225088 0.0214348088988017 -1552.69053375381 555.750225567379 -2.79386397399774 0.00552719962226459 IER2 other 1 1 1 2.31177687225088 -2.79386397399774 1.08062427114675e-17 100.114391213159 10.9871095773175 9.11198623338045 9.29806310951148e-18 -21.3109209078876 48.0364088979924 -0.443641008909353 0.65760384961855 ZNF394 other 1.53621546386222e-13 1 1.36374691627205e-13 9.11198623338045 -0.443641008909353 3.08635498333078e-13 155.25759708273 20.2529715274292 7.66591691853511 2.17399102045044e-13 -43.1434462548305 88.5474031950557 -0.487235590182045 0.626427079115783 CPSF4 essential 4.1091730248066e-09 1 3.07706689034555e-09 7.66591691853511 -0.487235590182045 0.000160677613041695 2063.14993413108 584.752059929444 3.52824739835891 0.00047956552713111 -5765.81746467388 2886.94254391688 -1.99720547844747 0.0466493450691363 LY6E other 1 1 1 3.52824739835891 -1.99720547844747 9.07665921138123e-05 311.378621791064 73.2087600183882 4.25329730639958 2.76875581448729e-05 -189.386092116683 360.773111230801 -0.52494514203284 0.599984817593397 VPS28 essential 0.785584854745045 1 0.301212945058072 4.25329730639958 -0.52494514203284 0.000361396082628863 112.601252759034 29.7101659077414 3.78999070919675 0.000180001089901157 -133.773867483727 146.41183632979 -0.913682054928975 0.361571830266604 TONSL essential 1 1 1 3.78999070919675 -0.913682054928975 6.3383833207912e-11 163.39333757847 39.6972043682823 4.1159910421556 4.91737119010293e-05 -188.85073524972 65.360922125463 -2.88935237001726 0.00412549676393816 MUM1 other 7.98699682252899e-07 1 0.524929374543488 4.1159910421556 -2.88935237001726 0.00661526327451837 126.849267637962 41.6368218911439 3.0465646001897 0.00250793240359413 -120.848131292822 205.162324795691 -0.589036663593902 0.556253563191582 RECQL4 ts 1 1 1 3.0465646001897 -0.589036663593902 7.11665893623699e-11 123.441420762902 17.6213881938663 7.0052040965688 1.46902172162843e-11 -24.6013480923894 86.8280719751553 -0.283334036248424 0.777104573602545 LRRC14 other 8.94848694642439e-07 1 2.02592785629777e-07 7.0052040965688 -0.283334036248424 5.89804383298788e-06 39.8827137453019 8.01358726567814 4.9768864333852 1.06219688955002e-06 15.5795114697804 19.7836291793481 0.787495121776936 0.431580486036081 ZNF333 other 0.0574705391086339 1 0.0126486405607616 4.9768864333852 0.787495121776936 0.481503762267243 39.1993772695175 33.8286926206131 1.15876122406315 0.247417524107683 -8.71104167969144 140.742059007919 -0.0618936637782263 0.950686153136628 COL26A1 other 1 1 1 1.15876122406315 -0.0618936637782263 4.54151308473822e-08 133.39598124842 22.3730005532176 5.96236436552698 6.58908842014119e-09 39.5286081091966 110.241286382372 0.358564467146108 0.720158111984224 PPP1R16A other 0.000509921089154407 1 8.56779167270958e-05 5.96236436552698 0.358564467146108 3.15491614280993e-05 81.3099262775002 18.0695973907678 4.49981947683258 9.54132478439152e-06 -48.1100259979891 89.0365892599644 -0.540339947855818 0.589339654842506 FOXH1 other 0.287452921020681 1 0.107301738525267 4.49981947683258 -0.540339947855818 0.00519229688900581 70.6200769688065 35.263584080541 2.00263469554065 0.0460651269715126 -278.466921713369 139.623196153401 -1.99441732738609 0.0469599084751446 ORAI2 other 1 1 1 2.00263469554065 -1.99441732738609 8.66075845062359e-11 57.8493472053329 9.24460300142984 6.2576345567663 1.26216916991255e-09 -57.9757490868892 36.6032282844788 -1.58389715345062 0.11421107947313 ALKBH4 other 1.08553946420116e-06 1 1.67527713922493e-05 6.2576345567663 -1.58389715345062 0.00319969571315059 16.8372415107456 5.56558338828135 3.02524287861671 0.00268693584549529 -17.1427258089143 22.036459463544 -0.777925593595215 0.437191267527417 SH2B2 other 1 1 1 3.02524287861671 -0.777925593595215 0.00331730754544165 700.290097521921 333.121356972519 2.10220714722801 0.036316250583688 -979.935971171296 531.295671150914 -1.84442679355644 0.0660450944398268 MRNIP other 1 1 1 2.10220714722801 -1.84442679355644 0.00178851908637638 1113.77368497208 605.740292973071 1.83869836280083 0.066886103523457 -2232.60472243626 966.095955009059 -2.31095546033554 0.0214706127189427 SQSTM1 other 1 1 1 1.83869836280083 -2.31095546033554 2.77127060295921e-06 312.384022740699 84.1595333358022 3.7118079242938 0.000242764833545589 -293.177973189931 134.07886933908 -2.18660833459518 0.0294972591131005 MGAT4B other 0.0277099347589892 1 1 3.7118079242938 -2.18660833459518 7.71609492621874e-09 203.048935247456 50.2444433269681 4.04122171134637 6.66968241903128e-05 -260.336961675016 80.0469998445857 -3.25230130024198 0.0012672511558975 MAML1 other 9.00391116940465e-05 1 0.703824367186826 4.04122171134637 -3.25230130024198 0.111522646182259 3.88679966841911 1.98679362480931 1.95631776742396 0.0513027777931698 -2.09216254417727 7.83499860386128 -0.267027813271875 0.78962083085808 FBXL13 other 1 1 1 1.95631776742396 -0.267027813271875 2.016438521761e-11 66.5859225869399 9.99808476209022 6.65986778181898 1.20512341246581e-10 -50.0286694718494 39.4278394968084 -1.26886662090372 0.205416616437369 NAPEPLD other 2.5749919922888e-07 1 1.63535247071611e-06 6.65986778181898 -1.26886662090372 0.0827381455996444 468.98910736944 455.335913227853 1.02998488312683 0.303799848504879 1616.48457987239 728.536095374072 2.21881193002852 0.0272052037244942 SCGB3A1 other 1 1 1 1.02998488312683 2.21881193002852 4.72728608465173e-14 498.715858411043 62.2520297983267 8.0112385094381 2.17096609279177e-14 34.7379049562221 245.493321735534 0.141502443775822 0.887562629015836 PSMC2 essential 6.38656350036449e-10 1 3.11121150757989e-10 8.0112385094381 0.141502443775822 0.000187385984077788 99.6831542366865 111.657437029145 0.89275875292272 0.37266358697467 -633.939029604918 198.339826600777 -3.19622659991997 0.00153268599487039 MFSD12 other 1 1 1 0.89275875292272 -3.19622659991997 0.0481757472277668 -7.95971947491456 5.99453593119773 -1.32782913744654 0.185214596492872 -56.1352154888207 24.3169594126568 -2.30848004210603 0.0216323216453552 USP41 other 1 1 1 -1.32782913744654 -2.30848004210603 0.803576264460718 1.1064888556552 2.67653522169924 0.413403435413315 0.679604450747953 -4.75459248426796 11.1175738887248 -0.427664572491843 0.669200134433926 TUBA3FP other 1 1 1 0.413403435413315 -0.427664572491843 7.01203137086785e-06 108.430248543349 22.2155476603774 4.88082716667573 1.67909027883265e-06 1.27112549584191 72.9641137036218 0.0174212421877032 0.98611155715705 YDJC other 0.0678624396072591 1 0.0197780043943698 4.88082716667573 0.0174212421877032 2.81313464764229e-36 1144.49404065646 80.0729166831126 14.2931478965076 3.8863166721551e-36 1165.32913582035 526.63523404721 2.21278232157912 0.0276226202728335 DVL3 other 4.28496669528874e-32 1 5.93051924170868e-32 14.2931478965076 2.21278232157912 6.43670991760272e-30 3358.06813905298 261.7350657619 12.8300276819149 1.18994063973654e-30 1406.90773917252 1721.41734466068 0.81729613305938 0.414371115672035 AP2M1 essential 9.72715602748123e-26 1 1.80894776052749e-26 12.8300276819149 0.81729613305938 3.95462042537127e-40 407.927700537612 26.8606598873299 15.1868085984749 1.49975846986683e-39 487.973340394809 176.661104558088 2.7622002116168 0.00607528344206068 ABCF3 other 6.04068269975461e-36 1 2.29208086949747e-35 15.1868085984749 2.7622002116168 3.70622205658653e-22 681.382733785167 64.2516778513175 10.604901795124 1.0227023664461e-22 723.324352275579 394.376041452586 1.83409811004592 0.0675678774295364 PCYT1A essential 5.45296451185576e-18 1 1.53303084730271e-18 10.604901795124 1.83409811004592 5.84162054661296e-08 152.817460863673 27.563570428993 5.54418235683032 6.1989785430579e-08 -50.9521800932813 86.4444911998219 -0.589420787676361 0.555996236656848 FBXO27 other 0.000652450598851202 1 0.000778281756080919 5.54418235683032 -0.589420787676361 4.64704758938252e-19 6617.69107897194 684.573376473672 9.66688350204407 1.45879342574189e-19 126.607075600657 3386.78291119588 0.0373826958858583 0.970203179224573 DMKN other 6.6912838239519e-15 1 2.15988954615344e-15 9.66688350204407 0.0373826958858583 3.63963152673353e-13 44.4114540937022 6.25095668503107 7.1047451344612 7.95169486586534e-12 -62.7325522228591 29.5103083805624 -2.12578436707151 0.0342915086919075 U2AF1L4 other 4.83743426218154e-09 1 1.10194587451162e-07 7.1047451344612 -2.12578436707151 4.0782995863339e-08 213.285365870043 35.6098756561998 5.98950043884551 5.72296810205775e-09 -42.1212200129076 225.109916472582 -0.187114013780188 0.851691319238222 BDH1 other 0.000459134967429471 1 7.45759973379146e-05 5.98950043884551 -0.187114013780188 4.9455532680737e-05 13.9295263800563 4.00391206585747 3.47897909617883 0.000573511925450773 -40.1671178301775 18.5291532723383 -2.16777945758277 0.0309170211001722 THAP8 other 0.441736817904343 1 1 3.47897909617883 -2.16777945758277 0.288816121637503 85.0248080055442 63.6806019450332 1.33517594696945 0.182773756336922 -75.4961258104579 179.573066521843 -0.420420095689989 0.674462540381219 COX7A1 other 1 1 1 1.33517594696945 -0.420420095689989 0.170552369770401 1.0560449475515 1.54577905540567 0.683179749304052 0.494990700238159 -6.62626643611884 4.44645318128271 -1.49023641225146 0.137153263022511 ZNF382 other 1 1 1 0.683179749304052 -1.49023641225146 0.00315074156157648 -13.9445865852233 11.2076997340073 -1.2441970177798 0.214337623201664 -69.8426334484654 21.0912046733519 -3.31145776308877 0.00103422815057959 LRRC56 other 1 1 1 -1.2441970177798 -3.31145776308877 0.0627296565449748 69.2356730804792 29.4339741165956 2.35223666387077 0.0192740827147899 -3.43102888539138 72.1000651995789 -0.0475870427563972 0.962075419446126 PLXDC1 other 1 1 1 2.35223666387077 -0.0475870427563972 0.00158539889997641 95.015117999929 26.5437935771739 3.57956061267883 0.000398586525130637 -26.2488663324137 66.481072719757 -0.394832171903463 0.693234810002707 PGAP3 other 1 1 1 3.57956061267883 -0.394832171903463 0.000362472270703711 -163.665354948311 43.9791312587196 -3.72143219440838 0.000234672847794049 -192.81787139242 110.149282726375 -1.75051408978671 0.0810062676152754 IKZF3 other 1 1 1 -3.72143219440838 -1.75051408978671 0.292807073987708 -7.56124817570085 4.81527867766057 -1.57026180245384 0.117342449439195 -2.95020790427228 11.4351047287584 -0.257995704827497 0.796576064625238 GRIN2C other 1 1 1 -1.57026180245384 -0.257995704827497 0.245803648776603 62.3723361641721 51.9916108184941 1.19966154505037 0.231158282122592 -120.289912553333 123.467311971895 -0.974265258003794 0.330660741787028 FDXR essential 1 1 1 1.19966154505037 -0.974265258003794 5.03037177601652e-09 234.66312338677 39.5463155001564 5.93388082856522 7.7276605994479e-09 -134.020137383123 97.4594184767772 -1.37513787253982 0.170056720940954 SAP30BP essential 5.92225669190425e-05 1 0.00010022003031424 5.93388082856522 -1.37513787253982 2.00621585858306e-06 227.597604208167 52.0022909935385 4.37668417794223 1.63647028415271e-05 -273.175960376249 128.026131638695 -2.13375157774184 0.0336280233352851 ACOX1 other 0.0202607739558304 1 0.180944519318765 4.37668417794223 -2.13375157774184 4.31806799675824e-05 168.903285974413 39.677579176244 4.25689493867961 2.7314906049371e-05 -81.9789746713455 97.8832394326058 -0.837517997427837 0.402930462863504 PRPSAP1 other 0.388064770868663 1 0.297322752347404 4.25689493867961 -0.837517997427837 0.856098647470406 9.36211143086774 32.4926161066744 0.288130429391453 0.773434014141023 -32.6764385948893 78.3647209764865 -0.416978943939505 0.676974269315956 CYGB other 1 1 1 0.288130429391453 -0.416978943939505 0.0342682546683577 7.23189896192143 2.9985234102168 2.41182007693532 0.0164374630989741 -3.07257411215418 7.40659154222442 -0.414843196717096 0.678535544228888 ZNF577 other 1 1 1 2.41182007693532 -0.414843196717096 0.026599467110279 19.2396093749999 11.7853136753078 1.63250719540118 0.103556263359677 -47.0224404761906 27.0016937098458 -1.74146262754786 0.0825634928874754 TMEM143 other 1 1 1 1.63250719540118 -1.74146262754786 1.81340565864771e-05 84.2798979119446 63.8151926712069 1.32068703993698 0.187552415003376 -624.733545908548 149.318806971547 -4.18389055323482 3.70864622970362e-05 ALDH16A1 other 0.169118211725485 0.537419925146351 1 1.32068703993698 -4.18389055323482 0.0158273789055699 1176.31491169006 433.97124865572 2.71058259120585 0.00707881744613848 -580.510197302041 1208.59554070282 -0.480318003626309 0.63132946678997 ITGA5 other 1 1 1 2.71058259120585 -0.480318003626309 0.643664596482972 -6.7170009328358 7.39360128220217 -0.908488391036846 0.364306071875481 -7.45939054726367 17.2913929613017 -0.431393269701165 0.66647383215302 SIGLEC11 other 1 1 1 -0.908488391036846 -0.431393269701165 3.53434901039688e-08 533.300564562075 141.454102822264 3.7701314696553 0.000194278737329185 -1524.58539723249 393.944986942522 -3.87004644751308 0.000131891392811108 ZNF385A other 0.000399346094684743 1 1 3.7701314696553 -3.87004644751308 0.0910781747565728 18.3847147339771 8.48084100283485 2.16779382231452 0.0309159176891836 11.0590277898168 20.5987501731602 0.536878582285372 0.591726904851479 MPP3 other 1 1 1 2.16779382231452 0.536878582285372 0.0840111859518029 18.913130707173 10.0475692206183 1.88235883643995 0.0606973369345011 -25.4894731927344 24.2151282136554 -1.05262598520376 0.293309121503205 NAGS other 1 1 1 1.88235883643995 -1.05262598520376 1.44022738779009e-06 77.0199409722318 17.2303666739593 4.47001171998469 1.08819328500818e-05 -103.19239005866 41.5260177876679 -2.48500567972365 0.0134671943139725 LSM12 essential 0.0147407273140315 1 0.121747064726716 4.47001171998469 -2.48500567972365 0.580488092649083 2.21269167997625 4.54617896821391 0.486714600425325 0.626793783675933 10.5033470356696 10.960055852703 0.95832969985087 0.338620011963906 ASB16 other 1 1 1 0.486714600425325 0.95832969985087 0.000280954735926374 524.89830667216 153.827414534306 3.41225462484191 0.00072702603365728 -536.17941314202 365.723618512326 -1.46607816941948 0.14360893606152 EMC10 other 1 1 1 3.41225462484191 -1.46607816941948 0.575019337783179 22.6989847525568 49.2221281678107 0.461154070282582 0.645001351950503 -96.3035308882473 117.025270683429 -0.822929358127809 0.411160987090396 JOSD2 other 1 1 1 0.461154070282582 -0.822929358127809 0.0341194781194305 4.47188401453563 1.85018667749989 2.416990711758 0.0162082889902357 6.58468886974111 4.39880608191364 1.49692638118672 0.135398074990572 SHANK1 other 1 1 1 2.416990711758 1.49692638118672 0.000699263807006918 22.6284161174611 6.23002807424554 3.63215315369208 0.00032722811387105 23.59254229157 15.0195265375716 1.57079134502362 0.117219342468914 FAM171A2 other 1 1 1 3.63215315369208 1.57079134502362 0.000153830980133558 33.3019083378494 10.6431125296999 3.12896328446397 0.00191569527928478 -67.2611173601593 25.9433441807774 -2.59261554298756 0.00996207204686337 DBF4B other 1 1 1 3.12896328446397 -2.59261554298756 0.0125268593525933 243.936175805371 81.8545671159731 2.98011686336033 0.00310276855144708 48.8444115215152 198.780281370482 0.245720607621438 0.806056535050993 PLCD3 other 1 1 1 2.98011686336033 0.245720607621438 0.186453578321369 79.6383762252371 61.5216778394511 1.29447666289375 0.196437071333024 -166.459751034492 165.299432884591 -1.0070194926241 0.314688639874683 FMNL3 other 1 1 1 1.29447666289375 -1.0070194926241 0.75120987367648 -14.0677976088069 80.1411866397524 -0.17553767542829 0.860768541144482 -165.317468248226 218.539993707471 -0.756463224161676 0.449929805380932 AQP5 other 1 1 1 -0.17553767542829 -0.756463224161676 0.195603614248617 78.1600845614141 69.1620252080881 1.13010115487876 0.259282600834789 -217.387404638623 188.600508521473 -1.15263424442927 0.249923540229482 RACGAP1 essential 1 1 1 1.13010115487876 -1.15263424442927 0.000240585149339105 182.25869005225 47.1489117143504 3.86559696555578 0.000134287608223678 -82.9398760802909 128.572127533949 -0.645084418148023 0.519336145575133 LARP4 other 1 1 1 3.86559696555578 -0.645084418148023 0.446917801797398 24.8875766838634 19.6685390319329 1.26534953325496 0.206669519301733 7.8059105788969 53.6348733591332 0.145537969794939 0.884378056279857 GRASP other 1 1 1 1.26534953325496 0.145537969794939 6.2751149348403e-09 285.229641149596 70.5671030734486 4.0419633048096 6.64508821304802e-05 -489.90955972739 150.604849039802 -3.25294678658001 0.00126407554285026 RAVER1 other 7.35255216915238e-05 1 0.701389060887218 4.0419633048096 -3.25294678658001 0.0975862624546707 778.539182725634 365.420713421346 2.13052833112924 0.0338926942552937 44.764793517976 991.976824452076 0.0451268541910766 0.964034432117863 KRT84 other 1 1 1 2.13052833112924 0.0451268541910766 0.0972721980579682 3.22686468875641 1.93068982203992 1.67135323961411 0.0956325677913039 -5.34163059082393 5.24108100150524 -1.01918489511797 0.308887520772631 KRT82 other 1 1 1 1.67135323961411 -1.01918489511797 0.338886658820894 -2.67130894083959 4.82601125766084 -0.553523147423068 0.58029789888338 -23.1394286493488 15.9686554446543 -1.44905303577672 0.148317529278793 SYCE2 other 1 1 1 -0.553523147423068 -1.44905303577672 0.0983450121799643 -7.68188250880737 34.14692655989 -0.224965561551614 0.822151012747106 -153.446945289211 72.6562294753723 -2.11195855327483 0.0354720327497971 SPC24 essential 1 1 1 -0.224965561551614 -2.11195855327483 0.29168948286025 20.3531485347509 13.6827018931451 1.48750946221723 0.137871186197975 2.35512361202395 31.7229676299615 0.0742403308383924 0.940865832882847 IP6K3 other 1 1 1 1.48750946221723 0.0742403308383924 2.73678363364042e-13 259.576131530544 37.9854501015151 6.83356734846721 4.23134034278145e-11 -112.869906477691 88.0682202528712 -1.28161902390676 0.200910002983862 LEMD2 other 3.64785890527932e-09 1 5.78593478471936e-07 6.83356734846721 -1.28161902390676 0.974527877664643 4.13773804972191 49.7871863511918 0.0831084934291101 0.933817235394514 -19.4672319986542 93.7310513689422 -0.207692453187447 0.835601224791812 ALOX15 other 1 1 1 0.0831084934291101 -0.207692453187447 0.784649878970276 0.00176878005687174 2.99432902997719 0.000590709985163256 0.999529052037494 -5.45600954227141 8.24064799963052 -0.662085013522727 0.508396248169425 ADCY10P1 other 1 1 1 0.000590709985163256 -0.662085013522727 2.3610545297534e-06 15.6015598516548 6.18718934897487 2.52159081800846 0.0121708306283838 -46.0185338844843 13.0541797785252 -3.52519535238721 0.000485319678801306 ZNF653 other 0.0237309590785514 1 1 2.52159081800846 -3.52519535238721 6.91045128992469e-14 61.9479937753495 8.96312513878542 6.91142796916746 2.60514534660472e-11 -68.4337407238773 16.874284416951 -4.05550475699771 6.28937114444871e-05 MED11 essential 9.31874356446345e-10 0.904034208303058 3.57712507542294e-07 6.91142796916746 -4.05550475699771 0.00285446277440531 167.867023054625 73.0239506413306 2.29879404743701 0.0221607067438183 -340.740358686763 137.477374608895 -2.4785195357136 0.0137080855659409 CXCL16 other 1 1 1 2.29879404743701 -2.4785195357136 0.000806826545394418 -7.23578437138145 4.83905430603435 -1.49528893741869 0.135824553040338 -38.2110564251742 10.8016732824986 -3.53751270065589 0.000463664638426311 SCIMP other 1 1 1 -1.49528893741869 -3.53751270065589 7.8244089740851e-08 820.553780954617 146.290962378583 5.60905313365239 4.40408168717383e-08 -412.911333845581 279.239889147731 -1.47869752815699 0.140204825980736 RNASEK-C17orf49 other 0.000868274663854224 1 0.000556059353822567 5.60905313365239 -1.47869752815699 0.637249227315604 8.62800132258598 10.3886420731008 0.830522532384318 0.406862616079569 9.8726871321487 19.8298186963928 0.497870771453125 0.618917095301952 BCL6B other 1 1 1 0.830522532384318 0.497870771453125 0.162263566559746 -1.82265899369119 1.56714264837679 -1.16304600323337 0.24567739078417 -4.69275185559119 2.99135867517871 -1.5687693670873 0.117689956442011 ASGR2 other 1 1 1 -1.16304600323337 -1.5687693670873 0.104704234270215 48.047022235441 31.7591708645976 1.51285505658461 0.13130344775417 -86.8703443756521 60.6218402521932 -1.43298758358807 0.152837611332628 TNFSF13 other 1 1 1 1.51285505658461 -1.43298758358807 1.59122989463292e-14 1573.76262755162 192.971451056886 8.1554168709012 7.99883663614112e-15 -581.130983200624 368.343510259732 -1.57768758513174 0.115625404086847 SENP3 other 2.16932371535306e-10 1 1.15031269664345e-10 8.1554168709012 -1.57768758513174 3.16270711263635e-06 295.290413119892 57.5860753608936 5.12780930579656 5.08664642720978e-07 52.7910605111573 109.920182619449 0.480267219841906 0.631365532597084 FGF11 other 0.0314815865991822 1 0.00614619487799757 5.12780930579656 0.480267219841906 4.11154323797512e-12 2853.11155347811 392.379855262086 7.27129977550047 2.75328044040375e-12 -1272.02445030201 748.973863495672 -1.6983562608782 0.0904125867000562 EIF4A1 essential 5.34212812910107e-08 1 3.84247818262747e-08 7.27129977550047 -1.6983562608782 1.11895403879268e-05 1205.71655709692 256.873705165532 4.69381074376585 3.98682653285481e-06 -542.618867332163 485.078337947504 -1.11862110690848 0.264143457281402 RPL26 essential 0.106278254604529 1 0.0459322284850202 4.69381074376585 -1.11862110690848 0.236486417895727 7.70424916647699 18.1193372115094 0.425194866486797 0.670985866562034 -70.3551672665342 48.8723619815797 -1.43956961386584 0.150985371818647 POLR3K essential 1 1 1 0.425194866486797 -1.43956961386584 0.246836260895159 22.5956865722825 36.9113428163481 0.612161055334861 0.540874225588956 -129.354357517269 99.5590780329911 -1.29927235238563 0.194803638207687 SNRNP25 essential 1 1 1 0.612161055334861 -1.29927235238563 0.0175833261891098 33.2321560298118 36.4221590019491 0.912415873755136 0.362241022647349 -226.842950593104 98.3224332288362 -2.30713320596072 0.0216894822061816 WDR90 other 1 1 1 0.912415873755136 -2.30713320596072 0.000335072575006944 420.393642052246 118.039999041545 3.56145074098388 0.000425209269088598 -242.070182467212 318.651618743225 -0.759670336595015 0.448014453002738 JMJD8 other 1 1 1 3.56145074098388 -0.759670336595015 0.55149183707001 -7.13456108666344 12.0109779101983 -0.59400334760466 0.552932190395307 -34.1526693177547 32.4239036330962 -1.05331762961736 0.292995118311999 CCDC78 other 1 1 1 -0.59400334760466 -1.05331762961736 0.000295755631211572 139.635779037643 46.1937998989249 3.02282512681735 0.00270658311828172 -231.785291239784 130.277768215577 -1.77916228082935 0.076162284731684 SPSB3 other 1 1 1 3.02282512681735 -1.77916228082935 0.30477755877079 12.1245598345537 10.6183822106251 1.14184624305776 0.254371631874053 -20.4753536767974 30.2849701589545 -0.676089610434809 0.499472083538233 MEIOB other 1 1 1 1.14184624305776 -0.676089610434809 0.399816049263468 14.9444118358161 14.8272103578091 1.00790448608866 0.314264215993993 -24.7361989250311 42.1221062105208 -0.587249811331912 0.557451350572044 HS3ST6 other 1 1 1 1.00790448608866 -0.587249811331912 0.0315541869164915 -24.3609388864993 49.6270800388679 -0.490879956415324 0.623847812305477 -374.011715125993 142.12146655004 -2.63163422250717 0.0089091793836802 CCNF other 1 1 1 -0.490879956415324 -2.63163422250717 0.107885482116133 13.5823996500854 18.5446602639985 0.732415663416252 0.46445100607319 -90.6008406483022 53.1079868355648 -1.70597392307158 0.0889832209924558 TBC1D24 other 1 1 1 0.732415663416252 -1.70597392307158 0.0211044605635219 26.2436988525288 26.4480915621391 0.992271929748501 0.32181460156373 -169.284464046703 75.7417433650544 -2.23502201726197 0.0261056710309246 AMDHD2 other 1 1 1 0.992271929748501 -2.23502201726197 0.0376965463220976 80.4895152350146 58.1729311961168 1.38362488497722 0.167440762547952 -284.059451685455 167.155032971646 -1.69937719873286 0.0902229953190602 BICDL2 other 1 1 1 1.38362488497722 -1.69937719873286 0.000946704035503303 91.5242051591516 70.0367883072164 1.30680185901273 0.192221293647634 -608.77797757077 200.511927365289 -3.03611852706253 0.00259390720037562 PAQR4 other 1 1 1 1.30680185901273 -3.03611852706253 3.15059507195076e-06 107.191292897206 21.9372001832765 4.88627956173375 1.62964046032443e-06 -9.9137889838841 62.8051399280642 -0.157849962522799 0.874674898408167 FLYWCH2 other 0.0313830775117015 1 0.0192069424653837 4.88627956173375 -0.157849962522799 0.650803677922046 -1085.18916872822 1750.39591460216 -0.619967836805004 0.535720175798489 -4184.17365193945 5012.76388277575 -0.834703917796049 0.404507146011057 ZG16B other 1 1 1 -0.619967836805004 -0.834703917796049 0.79076911677096 2.8476710938021 15.300457139065 0.186116732847899 0.852471145861517 -25.7314048450829 43.9709963011574 -0.585190398435561 0.558832115327334 ZNF75A other 1 1 1 0.186116732847899 -0.585190398435561 0.00542853317876729 90.7757192222826 34.407749194269 2.63823473920817 0.00874129223819496 -113.212664973562 100.062208785895 -1.13142280534508 0.258724358786646 ADCY9 other 1 1 1 2.63823473920817 -1.13142280534508 7.83511841061621e-16 106.366169285761 12.1722139381097 8.73844066712805 3.48985460228276e-16 -107.732468552742 176.262030323055 -0.611206329322822 0.541618333394267 SHANK2 other 1.09010002446903e-11 1 5.07006076619639e-12 8.73844066712805 -0.611206329322822 4.04252248166417e-33 163.349014045718 14.0165253567493 11.6540305024356 3.61888259619161e-26 -102.260666367716 52.2992136019563 -1.95530026791629 0.0514696888873272 CLPB other 6.13412361367721e-29 1 5.46378894373009e-22 11.6540305024356 -1.95530026791629 7.89734538980706e-18 59.1390914694236 8.15406077066996 7.25271654610989 3.18929605110985e-12 -61.3513507795321 27.7125678632869 -2.2138457569935 0.0275553780971184 NEU3 other 1.12418711623903e-13 1 4.44525006785302e-08 7.25271654610989 -2.2138457569935 3.91519494613328e-12 262.794115106074 34.7805897875615 7.5557693734123 4.41133076960076e-13 281.142288229406 162.110591102008 1.73426231018119 0.0838345622349148 CYB561A3 other 5.08818735199481e-08 1 6.21688845359835e-09 7.5557693734123 1.73426231018119 0.412381498276752 -3.48514321925015 2.66578249174252 -1.30736218354111 0.192031237783508 -5.93789444572255 9.42807804784248 -0.62980964047931 0.529269970475115 PPP1R32 other 1 1 1 -1.30736218354111 -0.62980964047931 0.000998405487531096 -66.0336479383855 18.0309133287993 -3.66224642835565 0.000293594387644234 -122.34282881397 67.0006130837901 -1.82599566157655 0.0688065549005318 ASRGL1 other 1 1 1 -3.66224642835565 -1.82599566157655 0.00037601684011935 209.969721134204 86.1094006775899 2.43840648619041 0.015307992048722 -747.00684707479 315.671997144742 -2.36640200534567 0.0185705680252616 UBXN1 other 1 1 1 2.43840648619041 -2.36640200534567 0.055884271976135 75.11608039884 61.7434327608464 1.21658412951853 0.224679073740319 -373.083201554852 226.347792190139 -1.64827409158668 0.100299806767516 LBHD1 other 1 1 1 1.21658412951853 -1.64827409158668 1.74613448032134e-05 32.9573037717028 8.51951617602457 3.86844781919078 0.000133273960128017 -48.6137795690641 31.2320451057619 -1.55653526384334 0.12059137682025 TTC9C other 0.16307149911721 1 1 3.86844781919078 -1.55653526384334 0.00771437574464073 17.1264588311608 12.9732721817936 1.32013408731189 0.187754850216522 -114.70479448384 48.6638713132945 -2.35708321981576 0.0190346338611206 TAF6L other 1 1 1 1.32013408731189 -2.35708321981576 6.34909323538175e-05 130.651626960586 42.4747156970655 3.07598590870881 0.00228322720228289 -354.25363841501 159.326349573666 -2.22344665124721 0.0268993408661934 NXF1 essential 0.558910677510655 1 1 3.07598590870881 -2.22344665124721 1.01449519425707e-09 163.504662715463 29.7085596781603 5.50362132956787 7.7537594385138e-08 -224.333423889441 111.439388985474 -2.01305324743555 0.0449649177642042 STX5 other 1.22531691320124e-05 1 0.000970072843352461 5.50362132956787 -2.01305324743555 0.408111187952282 8.10882937778944 6.0484733064197 1.34064068186974 0.181006240145753 7.21618102076027 26.7654657631601 0.269607900143199 0.78763900995163 SLC25A45 other 1 1 1 1.34064068186974 0.269607900143199 4.12035385248344e-14 2086.05097953309 741.533956370468 2.81315637889805 0.00521001362996005 -5329.63595659833 1051.14988834546 -5.07029113135079 6.74728956414811e-07 RPL29 essential 5.5715424793281e-10 0.0101276816357863 1 2.81315637889805 -5.07029113135079 0.525322484240962 -5.51223224964664 5.0199510426009 -1.09806494184268 0.27300165974239 -2.49687238165897 7.24173432918485 -0.344789282257476 0.730479289830658 ITIH3 other 1 1 1 -1.09806494184268 -0.344789282257476 2.9704030341397e-10 165.467834868887 25.0844217479607 6.59643808142954 1.77976709636015e-10 -43.3989103472713 105.733735926651 -0.410454714069478 0.681751460255987 ZFPL1 other 3.66518030382498e-06 1 2.40642309098856e-06 6.59643808142954 -0.410454714069478 4.55854286407945e-13 647.248418466576 101.136704035148 6.39973810340542 5.55145613662776e-10 -1110.34492442079 402.848092670171 -2.75623726318564 0.00618340665123379 RPS6KA4 other 6.04690710920139e-09 1 7.43284462133091e-06 6.39973810340542 -2.75623726318564 4.96931631101195e-11 433.837735670621 64.1858591579535 6.75908590088355 7.31023128412606e-11 -181.274858648101 312.690338586387 -0.579726445874887 0.562537129159898 LRP5 other 6.2797250222258e-07 1 9.95507296272287e-07 6.75908590088355 -0.579726445874887 5.21295726868446e-67 148.705425115187 6.29642566922841 23.6174351810318 1.9138498047335e-67 10.2280504058099 87.9933083941289 0.116236684271464 0.907552015720419 TPCN2 other 8.00397459033813e-63 1 2.93852499018781e-63 23.6174351810318 0.116236684271464 8.82875333310586e-05 87.2800453093374 19.9355833223681 4.37810340926456 1.74334425189084e-05 65.1945214956634 291.837911709769 0.22339291394224 0.823407182485847 FGF19 other 0.76483490124696 1 0.192395471638673 4.37810340926456 0.22339291394224 0.0828563699361886 144.894083889525 247.883766957542 0.584524294058926 0.5592794924315 -1271.77856590988 629.061521012585 -2.02170777170209 0.0440385017420851 PDZK1IP1 other 1 1 1 0.584524294058926 -2.02170777170209 0.719975262451393 2.32355459986781 4.69033663606396 0.495391862068495 0.620663548247861 -6.45138093775308 11.9027975674132 -0.542005432018379 0.588191971457418 TAL1 og 1 1 1 0.495391862068495 -0.542005432018379 5.73391006249575e-06 274.649290459829 102.774180445547 2.6723569019881 0.00791784930361057 -943.863261211523 256.14043681959 -3.68494437243552 0.000268549841031939 CMPK1 essential 0.0559228248395211 1 1 2.6723569019881 -3.68494437243552 0.469454651386027 -9.1608366909161 7.49150027074895 -1.2228307227973 0.222293453805036 -7.241362969038 18.7246242477324 -0.386729414338712 0.699213577458385 BEND5 other 1 1 1 -1.2228307227973 -0.386729414338712 6.19503410128426e-11 144.43532381645 25.4455918793027 5.67624146852458 3.1028085283773e-08 -178.373731946975 61.5696592200118 -2.89710442134458 0.00402750194019506 COA7 other 7.80822098125868e-07 1 0.000393932570762781 5.67624146852458 -2.89710442134458 0.107143180513333 58.9140097356811 31.8945440115379 1.8471500866847 0.0656541678650163 -46.0715246158799 77.1739252552167 -0.596983041403167 0.550943496183225 ZYG11B other 1 1 1 1.8471500866847 -0.596983041403167 1.04065243673469e-07 69.7597674316664 16.6729938689419 4.18399766592691 3.70989418922792e-05 -120.570552583949 40.3429621742494 -2.98863906083992 0.00302054551750548 C1orf123 other 0.00114752744198735 1 0.400186286192016 4.18399766592691 -2.98863906083992 3.24168756619634e-06 101.726123025637 31.1532874119398 3.26534152497334 0.00121252107864539 -234.686093443196 75.3803369414405 -3.11335957048736 0.00201782243265896 MAGOH essential 0.0322385828458226 1 1 3.26534152497334 -3.11335957048736 0.000351418092935642 87.3216065073714 41.6642866619536 2.095838270696 0.0368842989623882 -285.5827151625 99.8383135995623 -2.86045211368386 0.00450939678944144 ACOT11 other 1 1 1 2.095838270696 -2.86045211368386 0.000801903430167407 30.9851550584646 16.4139337173241 1.88773487160858 0.0599690337526375 -109.352593517679 39.3319937328743 -2.78024537124546 0.00575435610057787 FAM151A other 1 1 1 1.88773487160858 -2.78024537124546 0.000691694694314845 12.8822021943023 5.01142133436062 2.57056857422383 0.0106078975574972 -26.2703528585194 12.0070908476084 -2.18790323084397 0.0294041654429121 PARS2 essential 1 1 1 2.57056857422383 -2.18790323084397 0.0975391345458341 2.35258644335952 4.59766597563433 0.511691466023678 0.609222093463605 -21.1862369519196 11.0157556854961 -1.92326677867543 0.0553392194858074 LEXM other 1 1 1 0.511691466023678 -1.92326677867543 9.01255488372852e-08 296.217729078776 54.7594078297647 5.40943996325989 1.24785391567772e-07 -113.586550500253 131.183371588383 -0.865860887130236 0.387221286616323 USP24 other 0.00099759970007991 1 0.00154758842622351 5.40943996325989 -0.865860887130236 0.1994150160295 -154.102685433037 87.0218747724159 -1.77084998267452 0.0775405419497938 -151.644624065655 206.599917822528 -0.734001376495803 0.463487035723487 PLPP3 other 1 1 1 -1.77084998267452 -0.734001376495803 9.14241771816718e-12 97.8032428391894 20.8495408644719 4.69090631179551 4.04013030991555e-06 -186.969567236783 46.022119753015 -4.06260224953099 6.11451031997153e-05 NOL9 essential 1.17690343285966e-07 0.879144293805507 0.0465301807792974 4.69090631179551 -4.06260224953099 0.763124029922509 0.00891099367933463 29.4380516916131 0.00030270324180025 0.999758666966855 49.957935199326 69.9151897130952 0.714550520485376 0.475409383953569 PRKAA2 other 1 1 1 0.00030270324180025 0.714550520485376 2.68370395118082e-08 676.735237026833 127.063947119772 5.32594219183931 1.8999061157314e-07 -325.823340358605 280.473907250478 -1.16168859895986 0.246230435453644 KLHL21 other 0.000305271324446818 1 0.00233878442846535 5.32594219183931 -1.16168859895986 0.152725522669993 -16.4127053497565 8.52948754569291 -1.92423111726616 0.0552149875137977 -1.68458885604518 21.6420225844665 -0.0778387902272265 0.938005090102373 ZSWIM5 other 1 1 1 -1.92423111726616 -0.0778387902272265 0.000102625345615825 33.7702877988444 18.2546373420512 1.84995665298985 0.0652444527827415 -123.741550566139 36.5783508410565 -3.3829177018896 0.000806559781329823 GMEB1 other 0.882783222987324 1 1 1.84995665298985 -3.3829177018896 0.758727568018755 -0.650622489976781 2.22194376140733 -0.292816812593263 0.769851957431492 2.82400885289074 4.9988649654555 0.564930013594279 0.572517182934603 SLC45A1 other 1 1 1 -0.292816812593263 0.564930013594279 0.319431609238748 165.443624344669 125.833480179955 1.31478223528481 0.189527517442102 265.383576227112 246.824029019435 1.07519343753284 0.283100676047025 SELENON other 1 1 1 1.31478223528481 1.07519343753284 0.0712404880772542 203.588132321233 94.5387534264341 2.15348864822569 0.0320270063897688 -49.8723181528458 220.097419332794 -0.226592016862484 0.820885675474049 AK4 other 1 1 1 2.15348864822569 -0.226592016862484 0.000422571617660009 477.357576570835 143.922558161763 3.31676689650211 0.00101542129937083 -420.241152001076 335.068767961147 -1.25419374225235 0.210686968079701 JAK1 og 1 1 1 3.31676689650211 -1.25419374225235 0.693163690435656 -19.2771676644332 23.7250436356136 -0.812524013043176 0.41709506824913 2.48538040677173 55.2347126284024 0.0449967110989135 0.964137996369431 RAVER2 other 1 1 1 -0.812524013043176 0.0449967110989135 2.75054131667973e-14 100.68556154221 15.2418182747437 6.60587600030961 1.65509526608082e-10 -102.548678998501 34.4776413761679 -2.97435308522543 0.0031600268875772 LZIC other 3.7349600539194e-10 1 2.23917838548074e-06 6.60587600030961 -2.97435308522543 0.0831829598285831 -32.5007893134815 14.657418341547 -2.2173611038553 0.0273007061981203 -10.885636698857 33.1688174459839 -0.328188869458024 0.742983500536033 RBP7 other 1 1 1 -2.2173611038553 -0.328188869458024 2.55544574966466e-07 1035.66686498432 204.239956337082 5.07083375632452 6.71892370432001e-07 -269.201387003174 413.036081563173 -0.651762398055775 0.515022287648313 FBLIM1 other 0.0027570704193132 1 0.0080707711536292 5.07083375632452 -0.651762398055775 0.159070044086275 19.1098954408296 12.0921829588299 1.58035116619496 0.115014368975491 -12.4373097548895 24.4541173844407 -0.508597777599733 0.611384644259663 SLC25A34 other 1 1 1 1.58035116619496 -0.508597777599733 0.0817366990270093 6.70588596338846 6.03688831583166 1.11081829123828 0.267480519558107 -17.7098736476933 11.7063191818545 -1.51284732396026 0.131305411838033 AKR7A3 other 1 1 1 1.11081829123828 -1.51284732396026 0.46023564051615 -3.42881191500457 3.63785458344005 -0.942536826681564 0.346628887567207 -8.20466702151155 7.66033517559503 -1.07105848940536 0.284950275879846 DRAXIN other 1 1 1 -0.942536826681564 -1.07105848940536 0.00122867518999254 932.467780303696 281.804172035811 3.30892113330813 0.00104332767509715 -290.164728216982 600.12393408791 -0.483508008488255 0.629065748291481 PDPN other 1 1 1 3.30892113330813 -0.483508008488255 0.808745540579678 7.79688407287138 12.2366234022261 0.637176107867548 0.524467152870703 1.77640047953258 26.1868064776513 0.0678357050161353 0.945958918964545 LRRC38 other 1 1 1 0.637176107867548 0.0678357050161353 0.725123721692023 -152.100453831805 191.189413935802 -0.795548512340113 0.426884213953324 -140.978800274441 409.15151291015 -0.344563800514164 0.730648660743855 DHRS3 other 1 1 1 -0.795548512340113 -0.344563800514164 0.705901689557025 -201.39196416924 278.076976420182 -0.724230990863951 0.469458088095034 136.524472501528 570.403279224923 0.239347278450154 0.810990983726228 LAPTM5 other 1 1 1 -0.724230990863951 0.239347278450154 0.465068875539808 130.015806409532 109.404042615352 1.18840038541033 0.235565252384762 -15.5850592617793 224.414208869867 -0.0694477383596362 0.944677018250399 SDC3 other 1 1 1 1.18840038541033 -0.0694477383596362 2.02787151444875e-06 130.893628322199 73.9396793896522 1.77027584380515 0.0776392834422346 -693.177687891975 158.126005904453 -4.38370452682417 1.58750528708639e-05 PEF1 other 0.0204652793238168 0.232474274240931 1 1.77027584380515 -4.38370452682417 5.6819933721296e-06 104.422834824814 26.1410725091321 3.9945887755116 8.05668111725056e-05 -120.531176683201 58.7556378649643 -2.05139763711208 0.0410470871629003 SYNC other 0.0554335273384964 1 0.843051112109098 3.9945887755116 -2.05139763711208 0.00295639405266163 99.4230244198404 135.551771583687 0.733469015257088 0.463812794683755 -949.175435907202 304.67115686792 -3.11540956375692 0.00200426699262861 RBBP4 essential 1 1 1 0.733469015257088 -3.11540956375692 0.00681099975347556 670.768663541785 289.809524582713 2.31451559263831 0.0212782006283153 -1048.33266684343 651.263142296613 -1.60969138088575 0.108460578452687 KIAA1522 other 1 1 1 2.31451559263831 -1.60969138088575 0.0961843093070057 0.500724030180647 2.51228243542761 0.199310405199493 0.84214772124145 -11.6467802953524 5.64366789458572 -2.06368987560833 0.0398607596330113 TSSK3 other 1 1 1 0.199310405199493 -2.06368987560833 0.0104442489681746 -32.1653890362797 34.2528277047236 -0.939057917015243 0.348409266586041 -202.405009651682 66.5356861298201 -3.04205188861753 0.00254412455050516 TMCO4 other 1 1 1 -0.939057917015243 -3.04205188861753 0.569067698091046 -11.1883662777132 17.7239891317069 -0.631255537033593 0.528325499371712 -34.5130909425148 34.5558779048047 -0.99876180363851 0.318667088963177 UBXN10 other 1 1 1 -0.631255537033593 -0.99876180363851 0.0188791041167977 65.2171265210307 62.9503587135659 1.03600881478339 0.300982727929449 -274.655591195872 122.732241235591 -2.23784384959333 0.0259211649661189 CAMK2N1 other 1 1 1 1.03600881478339 -2.23784384959333 0.574607263050593 -24.7729384773262 24.5746776937393 -1.00806768601638 0.314185990133176 -0.00362879918891549 47.7858589494939 -7.59387665868026e-05 0.999939457096568 ALPL other 1 1 1 -1.00806768601638 -7.59387665868026e-05 0.00510154025165585 217.037682110453 108.958493627376 1.99192990729748 0.047228290561445 -400.547810117525 210.659992413938 -1.90139478088685 0.0581483756159898 WNT4 other 1 1 1 1.99192990729748 -1.90139478088685 0.104600545199118 94.8013628041557 57.8172758333834 1.63967190493983 0.102071645061646 -110.898430236565 131.150662758379 -0.845580402753091 0.398428698774652 SCNN1D other 1 1 1 1.63967190493983 -0.845580402753091 0.283563259620141 280.911368974266 177.885922836618 1.57916581871559 0.115301650311244 105.309949680818 403.510133245292 0.260984646987293 0.794274888105037 MXRA8 other 1 1 1 1.57916581871559 0.260984646987293 0.000139460238061409 212.076592242414 74.1149844796429 2.86145364168113 0.00449642462704781 -371.162467217977 164.740704687352 -2.25301007375425 0.0249397354926351 FAAP20 other 1 1 1 2.86145364168113 -2.25301007375425 0.0179539010132052 168.635495310761 64.1662433278729 2.62810298008374 0.00900018124258497 -42.1625369074935 140.92942798214 -0.299174824670663 0.765000864738838 MEGF6 other 1 1 1 2.62810298008374 -0.299174824670663 0.51054393807606 -1.79855642325935 8.24552859657828 -0.218125060412223 0.827470703979184 -21.2434600153026 18.3839267936097 -1.15554528984998 0.248729261636603 DIRAS3 other 1 1 1 -0.218125060412223 -1.15554528984998 0.00599243818179638 104.847081619875 49.1610583083013 2.13272629247223 0.033712782771549 -210.010908193654 117.17899885779 -1.79222309663634 0.0740477440733114 NFIA other 1 1 1 2.13272629247223 -1.79222309663634 0.079210105987404 18.6283416537458 12.6288244854382 1.4750653693244 0.141181237407808 -39.2521025740558 30.2619015081414 -1.29707984686606 0.195541043101095 OMA1 other 1 1 1 1.4750653693244 -1.29707984686606 0.0212067247606151 44.1993491335977 21.0762482746646 2.0971165530788 0.0367701791644696 -64.1866162725493 50.5040948335665 -1.27091905090217 0.204683449696505 MYSM1 other 1 1 1 2.0971165530788 -1.27091905090217 0.0636635367970197 1.01170611464285 14.3310032979017 0.0705956236009647 0.943763968298976 -75.6818286290816 33.529623660312 -2.25716308049899 0.0246761204263196 TM2D1 other 1 1 1 0.0705956236009647 -2.25716308049899 0.0229168958376513 9.49788738778905 69.4126110069154 0.136832302516942 0.891249397246993 -427.612128366824 162.444021971423 -2.63236604940778 0.00889042345870005 USP1 other 1 1 1 0.136832302516942 -2.63236604940778 0.0665264407373935 119.105707737313 75.4609734749138 1.57837491689541 0.115467482771028 -183.438020348234 160.625734168276 -1.14202136599145 0.254298942101402 FUBP1 other 1 1 1 1.57837491689541 -1.14202136599145 0.298882980635474 63.8493529906727 67.0045414029053 0.952910827442872 0.34135447595828 209.430839060061 142.625428215927 1.46839761801097 0.142978525700883 NEXN other 1 1 1 0.952910827442872 1.46839761801097 0.0654271987226475 75.5931095614955 37.6034675728872 2.0102696490682 0.0452414512467107 142.323936440353 80.0424949219071 1.77810470024966 0.07633614412315 DNAJB4 other 1 1 1 2.0102696490682 1.77810470024966 0.631344209647169 -16.5655628271555 18.0264452077402 -0.918958931517043 0.358811378283228 -1.07288752748437 38.1822774054671 -0.0280990972877575 0.97760068446881 ADGRL4 other 1 1 1 -0.918958931517043 -0.0280990972877575 7.4624369020349e-12 61.9309405943579 15.3934822221893 4.02319239405662 7.16992773007139e-05 -155.368700747796 32.4649733803374 -4.785733193975 2.60649237485398e-06 TYW3 other 9.63102106576624e-08 0.038826310415825 0.754348096480811 4.02319239405662 -4.785733193975 0.403969338248644 -2.70074748105285 4.14105218477341 -0.652188709667427 0.514747626212598 8.09732859555193 8.77188330445116 0.923100355364174 0.356650401210035 LHX8 other 1 1 1 -0.652188709667427 0.923100355364174 1.44600502961574e-05 39.9573179226242 25.2325024797041 1.58356540159915 0.114280412802327 -193.326168124697 52.1436058867313 -3.70757190334418 0.000246565293665162 SNX7 other 0.136141373538322 1 1 1.58356540159915 -3.70757190334418 0.481053807764834 5.43107980045422 11.3163632416965 0.479931554374532 0.631603938854507 -17.6666133759098 21.7932292600665 -0.810646883263038 0.418170956004981 NTNG1 other 1 1 1 0.479931554374532 -0.810646883263038 0.565004961271202 -24.4551691872658 35.2891342767434 -0.692994307978321 0.48881575934813 -69.396162835272 67.3428326613116 -1.03049070098205 0.303557943309142 FAM102B other 1 1 1 -0.692994307978321 -1.03049070098205 2.33182322782117e-06 -7.65309980860184 22.9206145956087 -0.333895924853083 0.738676795888324 -212.00063478716 43.7397840678606 -4.84686057110501 1.95927043662259e-06 HENMT1 other 0.0234441507325141 0.0292401519961555 1 -0.333895924853083 -4.84686057110501 0.00109479610741739 3.76970008154881 1.98795220594743 1.89627299402413 0.0588245035485918 -8.03010853956216 3.79822705499786 -2.11417285572641 0.0352737167437932 AKNAD1 other 1 1 1 1.89627299402413 -2.11417285572641 2.15380191851465e-07 38.9406944239714 11.396489865119 3.4169024747836 0.000715159506379993 -77.8031665866487 24.1391486534529 -3.2231114569784 0.00139873188488531 C1orf52 other 0.00233364437871062 1 1 3.4169024747836 -3.2231114569784 0.50739592291886 -92.0096008084893 185.014312261504 -0.497310719823885 0.619311477007986 -461.145864914942 397.945323045796 -1.15881714951547 0.247394755976164 GBP2 other 1 1 1 -0.497310719823885 -1.15881714951547 0.000261989279923537 7.87554803206338 6.72717122873672 1.1707072355199 0.242587542654587 -38.2146528471309 12.4958306077655 -3.05819229202598 0.00241471557394535 ATXN7L2 other 1 1 1 1.1707072355199 -3.05819229202598 0.0564313602971456 -312.29456220136 168.937618985998 -1.84857916239037 0.0654409606711893 -747.866167861968 363.366133896437 -2.05816144680978 0.0403841163795412 GBP4 other 1 1 1 -1.84857916239037 -2.05816144680978 0.398591371057897 -9.03992042948273 31.4200184682028 -0.287712129724913 0.773753927165072 -90.6247821310271 67.1601821908273 -1.34938261295254 0.178171002822768 ZNF326 other 1 1 1 -0.287712129724913 -1.34938261295254 0.0690594693659064 -14.3159085154679 10.1173895218161 -1.41498046354729 0.158046589614962 -47.2043984280589 21.4680476391137 -2.19882120729297 0.0286059609437706 GFI1 other 1 1 1 -1.41498046354729 -2.19882120729297 0.319205252883108 116.5170875376 77.2006417256801 1.50927615280226 0.132218027582996 101.775986475259 160.638418477088 0.633571890461404 0.526814238700201 AGL other 1 1 1 1.50927615280226 0.633571890461404 0.076755462641983 -714.885116233224 395.730399241221 -1.80649532511011 0.0717803291222094 -1572.28120252126 817.786899735005 -1.92260502464731 0.0554170925068182 VCAM1 other 1 1 1 -1.80649532511011 -1.92260502464731 0.0460947728493913 22.8088105258985 15.9801566146418 1.42732083770693 0.154462504488618 -47.0033016193103 33.0233986578368 -1.42333325852746 0.155613791376085 EXTL2 other 1 1 1 1.42732083770693 -1.42333325852746 6.30176293462335e-05 95.3449582317322 29.4604634415007 3.23636993766434 0.00133733009010209 -107.229724566111 60.9317868142344 -1.75983226772961 0.0793916968756282 SLC30A7 other 0.555059279281624 1 1 3.23636993766434 -1.75983226772961 1.77472018840898e-06 112.612117240558 23.0903613039484 4.87701841292977 1.70243405078581e-06 -148.141448561632 78.3162604574072 -1.89157970128311 0.0594526440543847 ZNF281 other 0.0179903385499019 1 0.0200444585139522 4.87701841292977 -1.89157970128311 0.00606352911475353 345.89306953181 107.583395868688 3.21511574103864 0.00143744203990806 -108.184300984133 369.355942154448 -0.292899852519214 0.769789134923223 ARPC5 other 1 1 1 3.21511574103864 -0.292899852519214 0.542444509825753 3.39247976459238 10.3863346995217 0.326629158672175 0.744161916220231 -38.4454748481077 36.0363503559933 -1.06685262154228 0.286842609124851 CADM3 other 1 1 1 0.326629158672175 -1.06685262154228 0.422363192667797 -3.64153472180704 14.196349473353 -0.256512051118657 0.797720309965142 -58.4482424870457 45.1065375400463 -1.29578206784669 0.195984442719203 NLRP3 other 1 1 1 -0.256512051118657 -1.29578206784669 5.91126222220463e-10 216.603113926038 32.1545559536932 6.73631177609715 7.55380269540256e-11 45.5228873094974 102.165749577467 0.445578753131742 0.656202857337143 ZNF496 other 7.21114878486743e-06 1 1.02845023697906e-06 6.73631177609715 0.445578753131742 0.694721157186569 0.888924441418973 4.29905323953842 0.206772140722411 0.836319320130496 11.4317951667936 13.6346594419874 0.838436428532261 0.402411476041675 TRIM58 other 1 1 1 0.206772140722411 0.838436428532261 0.024960397812208 12.942454633656 8.48923008607431 1.52457343038525 0.128353192298296 66.145651436234 29.7153676362645 2.22597452758788 0.0267120756615018 SLAMF9 other 1 1 1 1.52457343038525 2.22597452758788 0.000161336350298144 256.874618251124 61.0621468418563 4.20677345191283 3.36764313422731e-05 -131.467767188818 213.739541002876 -0.61508397824738 0.538936410377774 IGSF8 other 1 1 0.364378987123395 4.20677345191283 -0.61508397824738 0.0579558242604095 90.8341053566964 43.6620761478575 2.08038905546075 0.038285180707976 -187.637412569562 149.902163055609 -1.25173252169786 0.211581547898685 DDR2 other 1 1 1 2.08038905546075 -1.25173252169786 1.48092257344105e-06 451.762394367879 100.043563997572 4.51565674308487 8.88589950968487e-06 -1008.28162858284 350.188562883532 -2.87925345214139 0.00425470225800861 PEA15 other 0.0151320668554207 1 0.100179631072187 4.51565674308487 -2.87925345214139 3.33783250869761e-08 195.160634263894 33.122077881232 5.89216156557852 9.6561833331423e-09 -166.459655509105 115.939220770129 -1.43574930384552 0.152050461329161 PEX19 other 0.000377642370034047 1 0.000124777201030865 5.89216156557852 -1.43574930384552 1.00534672246312e-07 522.825576544215 90.5500467263295 5.77388522089179 1.8328986661013e-08 -287.515998833791 316.957827820884 -0.907111210379285 0.365030558117421 NCSTN other 0.00110929957356581 1 0.00023503259595417 5.77388522089179 -0.907111210379285 4.29931623987723e-07 467.613108934526 85.1198050392869 5.49358764060491 8.04469717713399e-08 -259.691984457075 297.950023055534 -0.871595785742472 0.384082377065869 VANGL2 other 0.00456716364162158 1 0.00100502401833935 5.49358764060491 -0.871595785742472 0.00677498155722555 -29.1234391044457 9.46835849889048 -3.07586992062652 0.00227994622152197 30.1669895559082 33.1426702838476 0.910216023559525 0.363393682468398 SLAMF6 other 1 1 1 -3.07586992062652 0.910216023559525 0.0738805998007017 209.970730724597 101.896010224033 2.06063741124846 0.0401455621240816 -372.038494920102 349.832937114433 -1.06347474880104 0.288368564112512 OLFML2B other 1 1 1 2.06063741124846 -1.06347474880104 0.0268480264022397 2.7378142424857 1.13818235407514 2.40542671627551 0.0167207531945635 -5.1092050850054 3.90764736541191 -1.30748877962452 0.191985377084379 FCRLB other 1 1 1 2.40542671627551 -1.30748877962452 0.260897295590773 -16.7678824482316 11.4738949002601 -1.46139411193765 0.144888558685613 -27.8550058712413 39.3925762576482 -0.707113078592648 0.480010818264694 FCGR3B other 1 1 1 -1.46139411193765 -0.707113078592648 0.000611077287486983 16.0829347445282 4.18847758739877 3.83980441793802 0.000148508603410299 -10.8447259970867 14.3907603854555 -0.753589505113802 0.451651589585341 KLHDC9 other 1 1 1 3.83980441793802 -0.753589505113802 0.304097331588276 74.9738558207348 50.066195398372 1.4974945714204 0.135253419022237 -61.0807946745838 170.026762070729 -0.359242238872812 0.719651552979917 C1orf74 other 1 1 1 1.4974945714204 -0.359242238872812 8.66488185571829e-08 98.1102873071855 17.0506226649719 5.75405891239029 2.0439036507759e-08 61.4707809364352 54.6139465034081 1.12555097867903 0.261201727481783 FLVCR1 other 0.000959982260795029 1 0.000261537911153284 5.75405891239029 1.12555097867903 0.439970636542579 25.6757283959498 193.521993562048 0.132676022623328 0.89453299484839 -832.014660521583 653.086952199875 -1.27397226007809 0.20359772660246 ATF3 other 1 1 1 0.132676022623328 -1.27397226007809 0.000769175905949498 10.9167014069828 12.3035851894771 0.887278076988452 0.375595575752982 -67.707886051763 22.8278173597024 -2.96602539721063 0.00324374072886485 RBM15 other 1 1 1 0.887278076988452 -2.96602539721063 2.4068471589022e-08 -27.025565954758 35.0629522854955 -0.770772687214296 0.441410383650138 -372.735947881896 64.8308177980542 -5.74936365977915 2.09077777473439e-08 DENND2D other 0.000274500918472796 0.000317191896204955 1 -0.770772687214296 -5.74936365977915 0.0636068314198866 27.2339128360231 12.9117614106298 2.10923296751769 0.035700961578377 -45.5597082733691 40.5594118053212 -1.12328325893996 0.262159221250351 TDRD5 other 1 1 1 2.10923296751769 -1.12328325893996 0.725133521260052 56.8662217271517 111.543196972616 0.509813446902662 0.610534687795324 -221.679853642149 348.663890761941 -0.635798141177477 0.52536385630465 IER5 other 1 1 1 0.509813446902662 -0.635798141177477 0.579233484109831 -16.4434138693364 24.3182563494049 -0.676175694222369 0.499419036279572 -44.7932446830591 44.0097832517632 -1.01780198340933 0.309543366248708 SNED1 other 1 1 1 -0.676175694222369 -1.01780198340933 0.000155528576185503 101.536687472892 23.951600819651 4.23924430928168 2.94039983690171e-05 5.68324564546438 77.9779921262093 0.0728826876725154 0.941945146702217 BPNT1 other 1 1 0.319356826285895 4.23924430928168 0.0728826876725154 0.499292095549355 4.77746497411772 4.15623673320432 1.14946892604802 0.251221052035668 3.02195134640702 13.5709251965241 0.222678358523488 0.823927909220286 SPATA17 other 1 1 1 1.14946892604802 0.222678358523488 0.158221398288775 52.7770842369268 28.4534226268593 1.85485890147734 0.0645388998761088 -54.6875532615127 92.6343413230477 -0.590359390269732 0.555367707984842 C1orf115 other 1 1 1 1.85485890147734 -0.590359390269732 0.000311396246496721 164.665448599127 40.5310704882015 4.06269675623448 6.1078858781324e-05 -51.6051003225829 132.724524939358 -0.388813599793718 0.69767261876717 BROX other 1 1 0.646519720200314 4.06269675623448 -0.388813599793718 0.0740285191781848 48.512367911386 21.5039728418549 2.25597233907227 0.0247852108506714 -40.1717321871498 82.6851976470943 -0.485839464986288 0.627432136907466 NBPF20 other 1 1 1 2.25597233907227 -0.485839464986288 7.20359012847348e-06 49.6697409602451 10.2078913385921 4.86581795521891 1.81996885225964e-06 34.8682160218419 41.5736145968137 0.838710233882678 0.402280273555359 ACP6 other 0.0696371057719531 1 0.0213682542943805 4.86581795521891 0.838710233882678 0.00686456554993825 148.609280697518 48.230469444953 3.08123230828451 0.00224160628576278 -118.828701893156 154.844938737111 -0.767404494214035 0.44341045803513 KIF26B other 1 1 1 3.08123230828451 -0.767404494214035 3.34856331655302e-10 103.237496825505 15.1410475194145 6.8183853655521 4.61875691958354e-11 33.1453536427433 47.9764332238861 0.690867399167999 0.490151278069757 TFB2M essential 4.12308601167173e-06 1 6.31153133061091e-07 6.8183853655521 0.690867399167999 0.000335601768609122 105.532610153023 26.3124350106905 4.01075043454343 7.54429645440478e-05 -38.7918177673948 83.3744679573565 -0.465272147670384 0.642054037282933 CNST other 1 1 0.792171021666221 4.01075043454343 -0.465272147670384 2.76942109104617e-13 116.736473413121 15.0560425927229 7.75346328188151 1.20215167124235e-13 -42.8067250161239 55.7778983567064 -0.767449586256723 0.443380138765084 PPP1R21 other 3.69108443014634e-09 1 1.70837774000251e-09 7.75346328188151 -0.767449586256723 0.57669070586455 0.288885730977517 18.7172821934414 0.0154341708369789 0.987695420504713 66.7515013236914 63.5644884221857 1.0501382608531 0.294446968613524 KLHDC8A other 1 1 1 0.0154341708369789 1.0501382608531 0.206676251682929 -112.508322731128 63.2355035130724 -1.7791954911511 0.0761598062386076 -72.3204793118708 219.956186399304 -0.328794931826022 0.742526436272512 PKDCC other 1 1 1 -1.7791954911511 -0.328794931826022 0.433143592056216 -5.74851473277181 4.4447285048192 -1.29333315331611 0.196831626568317 -4.13232517010883 15.7814892205574 -0.2618463386032 0.79360890474195 OXER1 other 1 1 1 -1.29333315331611 -0.2618463386032 0.245724191095251 11.6679236233926 8.61897154452262 1.35374894360889 0.17677483146702 -23.9309553070952 30.6025905462381 -0.781991160876968 0.43479980417714 HAAO other 1 1 1 1.35374894360889 -0.781991160876968 0.000125983309537044 67.4828320994519 15.7913265198018 4.27341123083172 2.54264202783885e-05 -31.7943261003529 50.7118608256338 -0.626960351734551 0.531132270033862 B3GALNT2 other 1 1 0.27737681881694 4.27341123083172 -0.626960351734551 9.17871596644731e-06 539.937875988821 113.968750054824 4.73759583858809 3.2568334514048e-06 -461.229098574202 387.041516951072 -1.19167861424155 0.234270339015035 MAPKAPK2 other 0.087886205378733 1 0.0377239018676218 4.73759583858809 -1.19167861424155 0.522748189613152 -2.70624319075364 7.58919951578751 -0.356591388212149 0.721632734809745 -28.0596608403203 25.7731640613918 -1.08871618453528 0.277098309128906 IL20 other 1 1 1 -0.356591388212149 -1.08871618453528 0.503510005049433 -26.0651240269686 65.5279911442671 -0.397770839175938 0.691064332752547 -246.932470697214 222.535151811644 -1.1096335508658 0.267990140515304 IL24 other 1 1 1 -0.397770839175938 -1.1096335508658 0.357600733574712 -18.8661598218938 13.1745805689033 -1.43201217854515 0.153116365979627 3.96737088089943 44.7412965934042 0.0886735786169484 0.929396799601784 FCMR other 1 1 1 -1.43201217854515 0.0886735786169484 0.89392649985116 145.871504586866 1027.20262646627 0.14200850039557 0.887162655607977 -1567.83706493192 3488.41294277933 -0.449441362203747 0.653417557137204 PIGR other 1 1 1 0.14200850039557 -0.449441362203747 0.120793562881295 363.27338572527 271.711182080657 1.33698356815302 0.182177664859391 -1440.31735816977 889.755368609481 -1.61877905881109 0.106479946076038 CAPN2 other 1 1 1 1.33698356815302 -1.61877905881109 1.24573450852858e-08 287.912815126049 46.6281000165446 6.17466324006107 2.00878527769132e-09 70.0865846338534 157.319216489515 0.445505553598563 0.656255687549841 MRPL55 essential 0.000143869878389965 1 2.65219920213585e-05 6.17466324006107 0.445505553598563 5.96880555470183e-06 382.2585934105 79.6337284133731 4.8002096727937 2.43675570340093e-06 -409.053238363558 260.771517887531 -1.56862697919326 0.117723153189897 WDR26 essential 0.0581182596861317 1 0.0284271920358752 4.8002096727937 -1.56862697919326 0.0325833726509171 125.696803855446 47.7779048762055 2.63085633790622 0.00892915464118093 40.0000507945573 199.718865947611 0.200281784120734 0.841387431290445 REL other 1 1 1 2.63085633790622 0.200281784120734 0.0508707456783862 16.6511739860904 6.88849826750449 2.41724296638644 0.0161990285742247 16.7084152911998 28.7771690182854 0.580613585741638 0.561910847160231 PUS10 other 1 1 1 2.41724296638644 0.580613585741638 0.000279251352721486 124.667815456173 30.4288621192077 4.09702521795841 5.31198462766017e-05 48.0868682117505 127.118636636569 0.378283385379835 0.705471694978035 PEX13 other 1 1 0.565354523921872 4.09702521795841 0.378283385379835 0.944863023407031 0.327431286143417 13.6667002332033 0.0239583279472188 0.980900828213612 19.6956585987711 58.4889484917971 0.336741540182302 0.736533170038767 KIAA1841 other 1 1 1 0.0239583279472188 0.336741540182302 0.165385175835286 10.3517744109424 5.5707225153429 1.8582462835712 0.0640521987720451 6.42962520069339 18.7464699154386 0.342977916892944 0.731840271698261 TRIM17 other 1 1 1 1.8582462835712 0.342977916892944 0.160033769320353 8.56512697991324 5.45262213268463 1.57082716745973 0.117229891956568 -9.36596424252388 13.3169432426833 -0.70331186908601 0.482382564929514 RFTN2 other 1 1 1 1.57082716745973 -0.70331186908601 0.411288624091883 15.5755355648061 11.7089320329868 1.33022683203952 0.184390795824403 2.67449251416568 39.4752088339385 0.0677511935507812 0.946026008807787 DISC1 other 1 1 1 1.33022683203952 0.0677511935507812 0.935751496316507 -1.87755393101799 27.3953729413812 -0.0685354397268274 0.94540221408162 -34.6962334549436 95.2492867420561 -0.364267645897488 0.715898737330956 CAPN13 other 1 1 1 -0.0685354397268274 -0.364267645897488 1.26547043092549e-10 85.2150191021968 13.048187549515 6.53079355112154 2.58019787743026e-10 -67.3431335907981 45.3719064564642 -1.4842473867704 0.13873070784876 MEMO1 other 1.57652306284698e-06 1 3.47733267941276e-06 6.53079355112154 -1.4842473867704 4.34612392095616e-05 106.644924652446 28.5789540291367 3.73158949567294 0.000225207158803432 -199.146528614077 99.3763788198905 -2.00396242023479 0.0459192530058013 DPY30 other 0.390542695537121 1 1 3.73158949567294 -2.00396242023479 9.64594774956367e-14 35.4506956721053 5.79176982718301 6.12087440107193 2.77243331263284e-09 -45.3702926977921 13.416200886133 -3.38175412569193 0.00081134305931664 TYW5 other 1.29709059388383e-09 1 3.6471360227685e-05 6.12087440107193 -3.38175412569193 1.35874219278673e-19 94.9873212471967 10.9973684721643 8.63727731662547 2.96119696542199e-16 -58.6696904781065 25.4241279396444 -2.30763826461955 0.0216691971786211 MAIP1 other 1.96691519827807e-15 1 4.30409978924086e-12 8.63727731662547 -2.30763826461955 0.822604503349438 1.64929487686904 3.31349231776939 0.497751230031318 0.619002336878239 -2.4159530723371 9.97371727816231 -0.24223195875292 0.808756088209228 KCNF1 other 1 1 1 0.497751230031318 -0.24223195875292 9.25641644596958e-06 64.2995087545969 14.4184041880649 4.45954406021034 1.13942285489143e-05 -40.3994061831058 43.8286142671421 -0.921758692548781 0.357351045715335 PQLC3 other 0.0885931618043749 1 0.127284927119921 4.45954406021034 -0.921758692548781 3.3054077074571e-06 219.247455458334 43.990635685676 4.98395742732411 1.02991546053485e-06 -34.7954223435457 114.913522387634 -0.302796586690393 0.762244743573449 ARL5A other 0.0328524472044161 1 0.0122704127968122 4.98395742732411 -0.302796586690393 0.352150168294855 50.7146238821686 142.65724536041 0.3554998118325 0.722451620987808 -577.232779480851 445.843407696643 -1.29469847376011 0.196366507997661 FAM84A other 1 1 1 0.3554998118325 -1.29469847376011 0.594514044395554 1.73160846016812 1.95982214407274 0.883553880338157 0.377600394470926 -2.98777830286928 7.76051346671852 -0.38499750250838 0.700495027929169 CLHC1 other 1 1 1 0.883553880338157 -0.38499750250838 0.00923374861751457 2.12712968830332 1.09124893028957 1.94926164806308 0.0521375849558056 -9.07244605733538 4.32113293783666 -2.09955263766484 0.03655107238664 PRORSD1P other 1 1 1 1.94926164806308 -2.09955263766484 0.242061466845237 -22.1879381934519 17.377319143815 -1.27683321056741 0.202595641520124 -77.8680824994893 60.8383463775822 -1.27991780079319 0.201509919606849 FRZB other 1 1 1 -1.27683321056741 -1.27991780079319 4.1487436353419e-07 13.467956572051 2.58475566854646 5.21053372121038 3.39890294669747e-07 -10.1664794772309 9.04928196133279 -1.12345703456604 0.262093522301741 DUSP19 other 0.00441094423309551 1 0.00413850422789884 5.21053372121038 -1.12345703456604 0.760911285056302 15.9720824017504 24.0415875723656 0.664352233548396 0.506943321274652 -21.9723894858921 95.1999979594633 -0.230802415513161 0.817615795613964 CFAP36 other 1 1 1 0.664352233548396 -0.230802415513161 4.01969012561427e-14 64.2763121421649 8.373820684851 7.67586440660792 2.06545079484967e-13 -54.7336476591519 29.3100874150409 -1.86739967316046 0.0627714387009376 NUP35 other 5.43703286390587e-10 1 2.92488487058662e-09 7.67586440660792 -1.86739967316046 0.243378501101949 7.59789300674795 8.1606597625681 0.93103906152276 0.352537417260149 -33.0690286512782 26.5435062960416 -1.24584251539556 0.213736435926979 CCDC138 other 1 1 1 0.93103906152276 -1.24584251539556 0.000460496683603039 69.5240282420802 17.5535471503821 3.96068257010759 9.21638251224679e-05 1.1422451330169 72.8485467708133 0.0156797243548384 0.987499673912172 FBXO41 other 1 1 0.959056764224401 3.96068257010759 0.0156797243548384 0.949775888795619 9.76119630216743 84.2253722563557 0.115893774532185 0.907809423232547 106.629774143424 348.523777954626 0.305946913490953 0.759844008025914 ACTG2 other 1 1 1 0.115893774532185 0.305946913490953 1.92985183919779e-08 52.8152850257743 9.18259899266157 5.75167064008594 2.0702383828181e-08 -36.1247095201008 30.8672806305335 -1.17032368197562 0.242744305224733 WDCP other 0.000221238214845634 1 0.000264887001081576 5.75167064008594 -1.17032368197562 3.24394222588228e-06 225.842945178642 49.7176079027254 4.54251430641058 7.91078451005766e-06 -209.820596302498 156.964057633534 -1.33674294272112 0.182265118222291 SMC6 essential 0.0322577614941734 1 0.0894393296707119 4.54251430641058 -1.33674294272112 0.00333964850972218 128.799389092722 83.3409703769668 1.54545103698864 0.123234898146642 -691.368925658107 263.11677953371 -2.62761244981539 0.00901684783232202 VSNL1 other 1 1 1 1.54545103698864 -2.62761244981539 0.257851136449483 -14.6117441516503 20.08376475595 -0.727540096650527 0.46742878870942 -85.4048377639811 54.5690296692724 -1.56507891530408 0.118555842578269 CCDC74A other 1 1 1 -0.727540096650527 -1.56507891530408 5.69193154282994e-05 428.606626102967 96.5374500426619 4.43979643043769 1.24123318705173e-05 175.221790424661 330.912001969458 0.529511741435214 0.59681765260469 H3F3A essential 0.504589731271874 1 0.138335438696915 4.43979643043769 0.529511741435214 0.153581776079434 313.675650932806 165.502686941401 1.89529038307316 0.0589549651107398 205.218214785948 567.31170590171 0.361738022767862 0.717786551585355 COQ8A other 1 1 1 1.89529038307316 0.361738022767862 0.151773980435457 26.2733919471988 22.7802792579717 1.15333932695336 0.24963186575923 -34.4792978734945 39.677868130137 -0.868980605520638 0.385509021296984 SLC16A14 other 1 1 1 1.15333932695336 -0.868980605520638 0.0411614388833421 56.8730367717483 22.4688014138248 2.53120029521267 0.0118535426775621 12.8842982546681 71.3980394208283 0.180457311701888 0.856909605888571 EN1 other 1 1 1 2.53120029521267 0.180457311701888 0.150001639002692 60.2905518503992 40.7377035018585 1.47996933228326 0.139927299254658 -53.0395972276709 86.5945331209519 -0.612505146873269 0.540666040736532 SGCB other 1 1 1 1.47996933228326 -0.612505146873269 0.187404172708871 -24.3371714397803 23.8363318572214 -1.02101160470323 0.30806884757388 -91.1768928991763 50.6679525613906 -1.7994982684312 0.0729412996752627 SPATA18 other 1 1 1 -1.02101160470323 -1.7994982684312 0.819884071599974 4.04658492432607 7.00666683537813 0.577533514779669 0.563985230156986 -3.32722988699197 21.0875628428695 -0.157781622835425 0.874728394683487 NOSTRIN other 1 1 1 0.577533514779669 -0.157781622835425 0.000153975801724983 45.8116977389838 112.77322302132 0.406228504530043 0.684846234231038 -698.249027850059 196.811545969649 -3.54780520832726 0.000446580907446784 SGPP2 other 1 1 1 0.406228504530043 -3.54780520832726 0.0185828442775465 94.0426293276237 35.7309259406891 2.63196731827571 0.00890723534493178 164.42223899836 113.540460475401 1.44813785596705 0.148573095290676 INHBB other 1 1 1 2.63196731827571 1.44813785596705 0.420243842489719 148.382779921029 454.280709705214 0.326632359136084 0.744160839930406 1687.34359513185 1283.31796607507 1.31482893541378 0.189514803982135 XIRP2 other 1 1 1 0.326632359136084 1.31482893541378 0.00028211713833842 25.728940251245 6.30221215265097 4.08252525114096 5.64101931969429e-05 5.44067481799947 19.0920648050511 0.284970477187992 0.775852261100466 BBS5 other 1 1 0.598399329433171 4.08252525114096 0.284970477187992 0.00055079407301572 120.180937411974 35.9058180131566 3.34711598459998 0.000914195625949636 -36.0252295478165 65.5352654572081 -0.549707539848748 0.582904623291476 SMARCAD1 other 1 1 1 3.34711598459998 -0.549707539848748 0.389464185341983 5.95845296962326 4.53534671227783 1.31378113904564 0.189863896108966 7.3960128863966 8.27791057763103 0.893463733032157 0.372282429183373 HPGDS other 1 1 1 1.31378113904564 0.893463733032157 2.73586010526271e-08 629.656040439239 163.21172594563 3.85790933090795 0.000138385443169386 -826.108452910444 297.89388955452 -2.77316347154966 0.00587802417848898 PDLIM5 other 0.000310985218165212 1 1 3.85790933090795 -2.77316347154966 0.380167403906081 -11.8170248818336 12.0888193387188 -0.977516873296739 0.329088017633638 -45.2198935759088 40.1667949864647 -1.12580288248407 0.261134035570399 NEURL3 other 1 1 1 -0.977516873296739 -1.12580288248407 1.01007174692711e-05 239.789474698672 49.1284904407571 4.88086388462981 1.67879961978431e-06 21.3802491583378 203.433433925326 0.10509702729683 0.916365495997424 RPRD2 other 0.0964012475267237 1 0.0197762595210591 4.88086388462981 0.10509702729683 0.320712547457695 96.1349947472855 105.079100699348 0.914882161223924 0.360976213246062 460.617310610482 347.927016269552 1.3238906123163 0.186530730483378 ANKRD23 other 1 1 1 0.914882161223924 1.3238906123163 0.92125643965639 -10.2963245106085 111.039359741855 -0.0927268000693225 0.926179364557566 -173.332840803988 442.429280784107 -0.391775247101174 0.695488355424001 CTSS other 1 1 1 -0.0927268000693225 -0.391775247101174 0.197848224705484 17.1609452977524 15.8513891045069 1.08261460144671 0.279794623219475 52.7942578007281 29.2796187624414 1.80310605233871 0.0723121548311665 MSX1 other 1 1 1 1.08261460144671 1.80310605233871 5.83499312300029e-09 32.3054573574899 8.2791835915803 3.90201002310707 0.000116461116569897 -30.2999461057814 15.3736081141316 -1.97090662652766 0.0496014867405436 PACRGL other 6.84969842709004e-05 1 1 3.90201002310707 -1.97090662652766 0.523711494048063 48.2137167411915 49.0112875205094 0.9837267939761 0.32600007022264 106.881117000381 195.411844965553 0.546953113406311 0.584795757132087 BNIPL other 1 1 1 0.9837267939761 0.546953113406311 0.0781146134700905 -10.689577690729 4.71502236278622 -2.26713191757001 0.0240553436281579 1.54914148953526 18.7991637350955 0.082404808605567 0.934376819749801 TNFAIP8L2 other 1 1 1 -2.26713191757001 0.082404808605567 6.87842687424665e-15 58.3235760347496 6.93807064861133 8.40631048437409 1.45251149214541e-15 -42.7259988758684 27.6626314984921 -1.54453848247219 0.123455615666745 LYSMD1 other 9.44339225565323e-11 1 2.10236513373126e-11 8.40631048437409 -1.54453848247219 0.528274069082477 26.2210848995922 27.4798441103538 0.954193364208811 0.340712815475759 -69.2424831229113 109.564292403519 -0.6319803797746 0.527855205387759 TMOD4 other 1 1 1 0.954193364208811 -0.6319803797746 4.56444235299758e-19 371.439805841169 37.8347649274476 9.81742073866314 4.88753335289091e-20 -134.755833700993 150.850173344593 -0.893309107396017 0.372369324481575 VPS72 essential 6.57416632102241e-15 1 7.26189705572532e-16 9.81742073866314 -0.893309107396017 0.000179949913675883 104.105365182591 33.8057374947739 3.07951764692857 0.00225475262996629 -223.220532141072 95.0760282008701 -2.34781086636757 0.0194985749608476 ERCC3 other 1 1 1 3.07951764692857 -2.34781086636757 0.000192232888214808 206.082360196291 54.5699383253906 3.77648145701502 0.000189804781314412 -187.419712913639 171.627373983542 -1.09201526868092 0.275653025462514 RNF149 other 1 1 1 3.77648145701502 -1.09201526868092 3.52680356552437e-06 145.517883941971 32.0358336589994 4.54234734425563 7.91666972786944e-06 -143.943440470236 90.0983102312816 -1.59762641608632 0.111122430763864 IWS1 other 0.0349717841557397 1 0.0894979512735641 4.54234734425563 -1.59762641608632 0.00332552659373435 47.7748481471597 14.0873391234395 3.39133229693239 0.000782754172518131 -7.788179806319 58.2932734056116 -0.133603404841034 0.893800173007122 BOLA3 other 1 1 1 3.39133229693239 -0.133603404841034 0.20886343453632 71.8914202814739 57.8497283075837 1.24272701678444 0.214878287494884 -205.933058614049 198.240074340721 -1.03880640329112 0.299679058036019 CDC42EP3 other 1 1 1 1.24272701678444 -1.03880640329112 0.469345642748204 927.78554349493 778.189615230283 1.19223583216332 0.234057701387135 1026.86176079325 3384.0612342527 0.303440655978558 0.761752493665234 S100A11 other 1 1 1 1.19223583216332 0.303440655978558 0.1716334699793 -790.440216026123 420.003038448727 -1.88198689929863 0.060747995257302 -49.4825324135804 1691.03792614243 -0.0292616337271981 0.976674223603619 LCE3D other 1 1 1 -1.88198689929863 -0.0292616337271981 0.474501554169122 -741.85677155775 765.997063457272 -0.968485137801225 0.333533546954102 2351.24651914268 3089.82882698696 0.760963357777813 0.447239325976906 IVL other 1 1 1 -0.968485137801225 0.760963357777813 0.510905942408429 3530.04070212593 3662.5451505921 0.963821756997387 0.335863072907341 8722.54755396266 13846.7237934093 0.629935837827169 0.52918609460555 SPRR3 other 1 1 1 0.963821756997387 0.629935837827169 2.07138670448791e-07 83.9733173207055 17.2184876558647 4.87692757918281 1.7031633302524e-06 -121.120878028193 58.9742234687444 -2.053793520357 0.0408104530178327 DHX57 other 0.00224621174234669 1 0.0200513418870615 4.87692757918281 -2.053793520357 0.796372552859316 -885.054793922454 1363.63633459322 -0.649040196033256 0.516777933089381 -857.483129584354 4979.56320883724 -0.172200470929373 0.863388781146931 SPRR2D other 1 1 1 -0.649040196033256 -0.172200470929373 0.912051693313316 20.8878772482472 48.7125404968993 0.428798765886102 0.668358188005554 0.836914947668169 174.937800072138 0.00478407152326743 0.996185858757224 PGLYRP4 other 1 1 1 0.428798765886102 0.00478407152326743 0.0254938375742001 -45.330869210613 17.1415921031129 -2.64449585183986 0.0085859463787176 47.9134288903923 73.8853040869612 0.648483882992473 0.517138559344532 ARHGAP25 other 1 1 1 -2.64449585183986 0.648483882992473 0.104649294625935 -16578.2061362976 7867.91535388813 -2.10706462774857 0.0358923389206438 -7089.24517796309 28769.4560152996 -0.246415683848628 0.805518953936089 S100A9 other 1 1 1 -2.10706462774857 -0.246415683848628 0.974063333342242 -16.6611686055296 92.6306920848855 -0.179866610413119 0.857371489120033 -45.8302557032788 338.473483158715 -0.135402795148323 0.892378813324348 S100A12 other 1 1 1 -0.179866610413119 -0.135402795148323 2.07025796128064e-06 479.168789698227 106.604505843128 4.49482679844077 9.74437060135236e-06 1222.33728396778 458.376965100828 2.66666385318665 0.00805018961435635 TGFA other 0.0208744110235927 1 0.109497492447396 4.49482679844077 2.66666385318665 0.964872473753492 -1.72591944487471 9.56754073570285 -0.18039321624565 0.856958066776599 6.93277459849655 33.8701063395191 0.204687122296026 0.837946710690045 TDRD10 other 1 1 1 -0.18039321624565 0.204687122296026 0.000528425468824111 50.629236031131 33.4122861558741 1.51528799301361 0.130699106021296 -167.178340836911 62.884441662392 -2.65850083768641 0.0082484663897966 FZD5 other 1 1 1 1.51528799301361 -2.65850083768641 0.00221580146267965 58.2357211079284 32.219167769908 1.80748682038645 0.0716312664652591 -89.6004266752347 60.4976351638236 -1.48105667986199 0.139581597792717 DCAF16 other 1 1 1 1.80748682038645 -1.48105667986199 0.0401234104951399 -40.9574064271893 22.6254249254332 -1.81023810877245 0.0712026780690198 -94.6238986306902 39.0389166668727 -2.42383515501047 0.0159150570343638 NPPC other 1 1 1 -1.81023810877245 -2.42383515501047 0.000105800029118414 28.6414504231422 11.8875531560005 2.40936465623162 0.0165555079697383 -41.2852969004608 23.0164404535587 -1.79373074580164 0.0738182233491 GNPDA2 other 0.908822250127172 1 1 2.40936465623162 -1.79373074580164 0.770387746730616 3.93688897077407 7.2188743686871 0.54536050493563 0.5858879050205 -2.18814575224781 12.4478362880495 -0.175785228983815 0.860574558226493 ALPP other 1 1 1 0.54536050493563 -0.175785228983815 3.78513295776423e-07 269.534080767515 55.2118099890954 4.88181932127835 1.66892351673134e-06 -51.1841067975604 104.840449286595 -0.488209533112948 0.625738955433122 PAQR3 other 0.00403911537923021 1 0.0196632568741286 4.88181932127835 -0.488209533112948 4.80375830567017e-09 103.281755100227 32.8210952902157 3.14681012888122 0.00181369287182413 -235.896266425641 70.5591577187275 -3.34324096336301 0.000931300611472841 NIPAL1 other 5.66026841157116e-05 1 1 3.14681012888122 -3.34324096336301 0.00151051490597449 362.822990374194 124.409702841265 2.91635605654585 0.00379406232906182 -194.695172223284 236.238752978143 -0.82414578374149 0.410476377570995 ANTXR2 other 1 1 1 2.91635605654585 -0.82414578374149 9.81186269414832e-07 23.2743845875931 6.78235259178917 3.43160935274427 0.000679566000002162 -29.7271406391892 12.7286571489409 -2.33544986649772 0.0201434133598113 HELQ other 0.0101680333099459 1 1 3.43160935274427 -2.33544986649772 0.000115011056661772 30.8653367314056 18.8499194743979 1.63742538918148 0.102533865499404 -104.504930134459 35.3762443086818 -2.95409906214413 0.00337049188885566 MRPS18C other 0.984379633968106 1 1 1.63742538918148 -2.95409906214413 7.95617445062534e-15 95.0725284534678 75.0634287178894 1.26656256018864 0.20630082253807 -664.014443412239 104.524148037316 -6.35273719882588 7.89518919375889e-10 CGGBP1 other 1.09110976415876e-10 1.20551643799504e-05 1 1.26656256018864 -6.35273719882588 3.31520125176277e-05 44.6002267299743 11.2489256757961 3.96484322284562 9.1181474586191e-05 -78.2479761443004 42.1210059362039 -1.85769485806712 0.0641573451779417 GPR155 other 0.301384945797753 1 0.949199150442248 3.96484322284562 -1.85769485806712 0.959962296414161 18.6807900105934 86.8609398369764 0.21506548335367 0.829853263604443 50.7053261498866 228.025125966866 0.22236727612752 0.824169839978104 DAPL1 other 1 1 1 0.21506548335367 0.22236727612752 0.0551827736019001 177.989081599381 79.7560280892258 2.23166932786897 0.0263289750569397 236.748298607769 282.344776701 0.838507803735583 0.402371465280091 PMVK essential 1 1 1 2.23166932786897 0.838507803735583 1.15818191221483e-05 462.706978525026 97.7961662821557 4.73134066615711 3.35613722434407e-06 -441.056136187687 345.954396364194 -1.27489675177701 0.203273577004477 PBXIP1 other 0.109911463469187 1 0.0388472883717826 4.73134066615711 -1.27489675177701 0.0157909873894905 1567.59443230853 543.934034796841 2.88195687716807 0.00422186758614659 -1044.70635646569 3340.29141039338 -0.312759046475724 0.754669384514259 CLDN1 other 1 1 1 2.88195687716807 -0.312759046475724 1.01542345496609e-12 324.952926722542 41.873699656299 7.76031087269022 1.1571699799606e-13 -87.9963647379602 148.128408697895 -0.594054614583938 0.552896620830301 PYGO2 other 1.33771885957233e-08 1 1.64514856050999e-09 7.76031087269022 -0.594054614583938 0.0003455667625517 147.219080265338 91.1307094740429 1.61547167925068 0.107197143924689 -416.555192269181 166.04116985719 -2.50874643094514 0.0126116913010385 HIPK1 other 1 1 1 1.61547167925068 -2.50874643094514 0.459253179396561 3.18597595944306 3.21938091443733 0.989623795418411 0.323110425105321 8.11208794990023 11.2855941629016 0.718800253917209 0.472791831741418 DCST2 other 1 1 1 0.989623795418411 0.718800253917209 0.294767548158156 2.61181267634713 1.6870274364865 1.54817439234221 0.122574910748032 -1.78834904686531 5.91390316830355 -0.302397417741 0.762546816267907 DCST1 other 1 1 1 1.54817439234221 -0.302397417741 0.348497151693682 3733.4405996416 2687.40391141073 1.38923687049401 0.165726672326889 1168.12718883169 4851.01077191311 0.240800782301914 0.809863728277967 COL6A3 other 1 1 1 1.38923687049401 0.240800782301914 5.74817455597406e-09 283.894868225242 44.7771857088689 6.34016773789808 7.80712439621762e-10 -68.1478032206267 156.346519969954 -0.435876687461435 0.663220088007787 YY1AP1 other 6.75065619853594e-05 1 1.04217303565109e-05 6.34016773789808 -0.435876687461435 4.35143038181968e-07 9.24508451277735 6.32041849699456 1.46273296889652 0.144528076518049 -32.8557033770661 8.85265054562936 -3.71139730498989 0.000243265527723798 KBTBD8 other 0.00462078392245432 1 1 1.46273296889652 -3.71139730498989 3.42077536919365e-09 28.7267968774039 36.3863432017677 0.789493924083261 0.43041163773273 -250.133710558481 50.5375657710641 -4.94946099484868 1.20917088368391e-06 EOGT other 4.05430296756832e-05 0.0180988697869807 1 0.789493924083261 -4.94946099484868 0.067559345746967 208.210158786986 97.2205357722215 2.14162735406852 0.0329830249450095 261.038219639016 135.031134995946 1.93317059541011 0.0541026862117071 LMOD3 other 1 1 1 2.14162735406852 1.93317059541011 3.61448495219523e-05 365.613502454046 81.3574051473174 4.49391793890198 9.78358441655364e-06 232.625331836215 272.729429151673 0.852952805862564 0.394323443528263 NAXE other 0.327363902120322 1 0.109908787335564 4.49391793890198 0.852952805862564 4.64998234107885e-10 134.664077761002 20.4824878480238 6.57459576005534 2.00040470823766e-10 -39.4591760427415 80.5772067224115 -0.489706427509685 0.624679297853982 POGLUT1 other 5.69762336252391e-06 1 2.70214667988743e-06 6.57459576005534 -0.489706427509685 0.00382432285375254 13.3077655512716 11.991099562536 1.10980360740639 0.267919558825229 -51.6650745852615 22.0385044015937 -2.34430947054308 0.0196754797367133 SLC22A15 other 1 1 1 1.10980360740639 -2.34430947054308 0.070337252894935 121.639585847461 52.6420939084494 2.31069049151059 0.021485445588932 29.507563236899 175.628657508901 0.168011095998974 0.866680683705616 IGFN1 other 1 1 1 2.31069049151059 0.168011095998974 1.91168233280413e-08 2060.73619124009 1360.12922367582 1.51510323825764 0.130736472870308 -11584.9903999367 2499.78859122877 -4.63438806008877 5.22481321209228e-06 ATP1A1 other 0.000219231729925978 0.0774421814296318 1 1.51510323825764 -4.63438806008877 0.0518297647152008 83.120096073446 34.0475534627452 2.44129423761376 0.0151762503778889 74.4767196805516 133.508856078539 0.557841044168182 0.577342972896361 SLC15A2 other 1 1 1 2.44129423761376 0.557841044168182 0.000417280379129494 -9.88454208146642 35.8132751250257 -0.276002182066819 0.782725667878095 -174.839070127893 50.0369023030593 -3.49420252015087 0.000542927326552721 EIF4E3 other 1 1 1 -0.276002182066819 -3.49420252015087 2.60086973584597e-16 431.178932651055 48.2231250169949 8.94133120777839 3.21576494504628e-17 158.689656175814 189.882984369583 0.835723415147852 0.403938004047643 LRRC58 other 3.63965710834285e-12 1 4.70209150264667e-13 8.94133120777839 0.835723415147852 0.445621454970904 22.4568083457975 29.1909732998274 0.769306597458686 0.442278781228243 -98.6482175674887 99.2828637989282 -0.993607696160691 0.321164620729713 LMOD1 other 1 1 1 0.769306597458686 -0.993607696160691 0.20498014469123 680.693825126551 417.273193840338 1.6312905673663 0.103812752208924 -966.055447914664 1419.20850824248 -0.680700152446949 0.496553468289327 ELF3 other 1 1 1 1.6312905673663 -0.680700152446949 0.493610548543227 -0.503222029240946 2.65198186662441 -0.189753193856289 0.849622841548067 -5.26185837610172 4.65291379308429 -1.1308738158705 0.258955040475124 TMEM169 other 1 1 1 -0.189753193856289 -1.1308738158705 0.891632406214807 42.9257777685656 306.454811501313 0.140072128606085 0.888691957808085 -239.067926503202 647.560416159527 -0.369182427673757 0.712238223518679 IGFBP7 other 1 1 1 0.140072128606085 -0.369182427673757 5.26548815043981e-05 10.6820208137393 2.63529135721079 4.05344964400643 6.35099121826594e-05 -19.8290723281262 9.23805835622314 -2.14645454309871 0.0325929776041326 TRIM46 other 0.468733755152152 1 0.67155381141944 4.05344964400643 -2.14645454309871 7.4021403017449e-06 279.50837672715 57.4327073097044 4.86671079633959 1.78958224683968e-06 142.476033996281 201.33132536984 0.707669478331584 0.479668854654042 KRTCAP2 other 0.071497273174554 1 0.0210275914003663 4.86671079633959 0.707669478331584 0.194228005974578 8.75401635283326 10.5828415070232 0.827189592419363 0.408746012526403 -19.6326713317671 18.5676417466346 -1.05735944282346 0.291145121547366 CXCR1 other 1 1 1 0.827189592419363 -1.05735944282346 1.94685359185203e-22 964.248828785109 285.54474688214 3.37687469061761 0.000823563519869753 -3809.644778266 500.9895082736 -7.60424063847957 3.21386727262966e-13 ARPC2 other 2.86907813831233e-18 4.92814407585031e-09 1 3.37687469061761 -7.60424063847957 1.84126448720265e-09 1297.82462035748 199.733875258272 6.49776918752159 3.12089883269561e-10 465.003478611827 697.401943029183 0.666765390116455 0.505402462102937 CCT3 essential 2.20233645314309e-05 1 4.19916937939194e-06 6.49776918752159 0.666765390116455 0.767214011119338 39.1149804230059 138.138884269803 0.283156915808074 0.777239642054289 -325.639361378794 481.009793172003 -0.676991125755207 0.498900677624738 TMEM79 other 1 1 1 0.283156915808074 -0.676991125755207 1.37939488894487e-11 1122.65506498847 152.861086713073 7.3442828984707 1.72894268579e-12 150.261259006312 532.273588950479 0.282300798171468 0.777895370971225 SSR2 other 1.76714279222728e-07 1 2.42034686583742e-08 7.3442828984707 0.282300798171468 1.04836877882247e-08 44.2324393387602 24.2284437579409 1.8256409607102 0.0688391655148668 -189.895920451504 42.5323000937568 -4.46474608786508 1.11368116042153e-05 RNF25 other 0.000121516425153312 0.163699993770361 1 1.8256409607102 -4.46474608786508 0.00120168432176627 28.9119470308714 16.4643756231199 1.75603057733159 0.0800428161469104 -60.0801655536517 28.9154873288034 -2.07778499011512 0.0385286644563137 STK36 other 1 1 1 1.75603057733159 -2.07778499011512 0.00236244086066755 13.8024264477822 4.22971272594488 3.26320659157741 0.00122061997417817 -17.3931500730786 14.3858852586139 -1.20904273601543 0.22753898005365 ADORA1 other 1 1 1 3.26320659157741 -1.20904273601543 0.051509833766621 2.59052037630454 1.12874770024747 2.29503933938167 0.0223858689255985 -2.3820416938848 4.09690211077185 -0.581425093760911 0.561368487131914 CCDC141 other 1 1 1 2.29503933938167 -0.581425093760911 0.000121372630310553 -11.9293167283741 10.0080790532091 -1.19196867500251 0.234156742464851 -62.2422753281723 14.8941704668588 -4.17896891046523 3.78259893899165e-05 EOMES other 1 0.54802293428111 1 -1.19196867500251 -4.17896891046523 1.05604888279259e-14 132.818289576471 17.3325896300817 7.66292241443001 2.23291320675647e-13 -130.384573582855 50.2913357167566 -2.59258521820115 0.00996710768723023 CWC22 essential 1.44603513608246e-10 1 3.16024206152243e-09 7.66292241443001 -2.59258521820115 2.02202337012804e-25 125.770983542667 25.331422675956 4.96501855231548 1.11931991878577e-06 -251.287688001559 37.6985958541925 -6.66570418095858 1.15396316457846e-10 AZI2 other 3.0194874986122e-21 1.76475586758984e-06 0.0133143104339567 4.96501855231548 -6.66570418095858 0.0576147773065303 286.643068720379 176.717395626097 1.62204217476624 0.105785303007804 -188.238720738188 262.78961798068 -0.716309579444752 0.474325914509295 TGFBR2 ts 1 1 1 1.62204217476624 -0.716309579444752 8.81832783916045e-06 31.8859785575171 34.0659911591122 0.936006188946247 0.349975828200627 -229.806223782592 59.7945319610853 -3.84326486462259 0.000146437547729608 ANKZF1 other 0.0845765823053879 1 1 0.936006188946247 -3.84326486462259 7.18418787041067e-11 124.365029590875 27.6721097339377 4.49423736703207 9.77967543544004e-06 -121.619222917917 44.5386902435035 -2.73064210584093 0.00667250965228646 HDAC11 other 9.02980573431917e-07 1 0.109874653517169 4.49423736703207 -2.73064210584093 0.188117234909151 -3.62220144832349 3.07866170813704 -1.17655065470488 0.240254859737261 -20.0586472834624 12.2887847525515 -1.63227265245229 0.103611854279388 TRAT1 other 1 1 1 -1.17655065470488 -1.63227265245229 0.0112961171274284 191.27968436401 288.796175648843 0.662334547658945 0.508235057619542 1351.71171112445 464.821928447228 2.90802053087285 0.00389229178316133 FBLN2 other 1 1 1 0.662334547658945 2.90802053087285 0.00352909369063506 7.88318110858672 18.6725902015545 0.422179302576375 0.673177651140338 -91.3426167111909 32.7751741139181 -2.78694527735253 0.00563852370344147 GLB1L other 1 1 1 0.422179302576375 -2.78694527735253 1.69122980885948e-17 752.621609771649 133.556665180178 5.63522313735752 3.83682773765032e-08 -721.192132721573 198.760993753432 -3.6284389562684 0.000331780841743239 STT3B other 2.39917860684805e-13 1 0.000485435445367518 5.63522313735752 -3.6284389562684 5.99722662813636e-29 73.9078085599113 10.9859671125037 6.72747404056881 8.00171160780809e-11 -111.580157817994 17.6820846315533 -6.31035085189457 9.30122655877882e-10 CHCHD4 essential 9.04081914191557e-25 1.41964620966641e-05 1.08879289847445e-06 6.72747404056881 -6.31035085189457 0.121627826728111 39.5338528097517 23.4622451897864 1.68499870707009 0.0929637400921764 -92.1127084879397 79.6785343786312 -1.15605425233127 0.248521337661158 NFASC other 1 1 1 1.68499870707009 -1.15605425233127 2.11654743654595e-07 60.6995074648825 15.2696478192317 3.97517403043397 8.72037620557948e-05 -105.264457102454 37.6980064557696 -2.79230832075851 0.00555216269192737 SGO2 other 0.0022943374212158 1 0.910145664576331 3.97517403043397 -2.79230832075851 0.00922169045704135 25.3226480075364 38.0590781606007 0.665351060282662 0.506312848397503 807.659193907549 269.409418692086 2.99788774211581 0.00293492688695721 SERPINI1 other 1 1 1 0.665351060282662 2.99788774211581 4.38461416081641e-12 166.997984906729 37.2531591879147 4.48278719300953 1.02762871553645e-05 -166.200549168276 55.4406995012606 -2.99780757933072 0.00293222885784998 CLASP2 other 5.69210610357186e-08 1 0.115197179011635 4.48278719300953 -2.99780757933072 0.00668968083004386 117.278174649822 52.5184623480258 2.23308469834191 0.0262410683269553 -451.985232441426 216.683896260836 -2.08591981333648 0.0377851418674164 SUCLG1 other 1 1 1 2.23308469834191 -2.08591981333648 0.0380063796354163 112.361375586187 43.8734069336776 2.56103602248263 0.0108943308502234 -26.4428654887657 148.995491880482 -0.177474265529973 0.859248161993871 NUAK2 other 1 1 1 2.56103602248263 -0.177474265529973 2.73133916174595e-28 430.266746647384 34.442878525052 12.4921831470743 2.15582304460131e-29 -121.747965265517 248.080375711641 -0.49076016156567 0.623935635534768 PRKCI other 4.11257737584088e-24 1 3.27210821709586e-25 12.4921831470743 -0.49076016156567 0.278552886643882 -15.5258922254582 11.3383779008785 -1.36932216946617 0.171858833138909 -31.7583175519999 39.9584761811605 -0.794782999432125 0.427328804671841 MNDA other 1 1 1 -1.36932216946617 -0.794782999432125 0.972077595082608 -0.965664419914687 4.09053628789745 -0.236072815873012 0.813527193001459 -0.349391423268549 14.453462093921 -0.0241735454798404 0.980729246613653 PYHIN1 other 1 1 1 -0.236072815873012 -0.0241735454798404 0.00332516020388978 1088.20577494416 323.121981687044 3.36778627459067 0.000850223439161926 -698.69553057907 1121.10164718006 -0.623222285273167 0.533582385077739 IFI16 other 1 1 1 3.36778627459067 -0.623222285273167 0.394795969369964 -56.7839300262237 41.919565589458 -1.3545925208849 0.176503043804212 -19.1549969398632 145.443815942338 -0.131700318887792 0.895304098213273 AIM2 other 1 1 1 -1.3545925208849 -0.131700318887792 1.68685815188796e-07 61.1427951617141 10.9444409634627 5.58665311145952 4.98749076350401e-08 -107.617605148817 78.8290974052847 -1.36520153967414 0.173157768016769 EIF5A2 other 0.00183766327066675 1 0.000628523586016775 5.58665311145952 -1.36520153967414 0.145699048820823 73.0997732053642 40.5319677717455 1.8035091120427 0.0722576423041799 219.674758649187 291.938020970957 0.752470534391411 0.452326529169222 RPL22L1 other 1 1 1 1.8035091120427 0.752470534391411 8.24221635763438e-05 103.427937086018 24.4345545461795 4.23285543800469 3.03569756437043e-05 166.935812313913 143.312295426307 1.16483942858729 0.244970998129668 PPM1L other 0.716248601478427 1 0.329464256661123 4.23285543800469 1.16483942858729 0.860105105010901 -1.7103385607027 6.26032072541453 -0.273203025167605 0.784876185200644 4.91596426700992 13.8158900369241 0.355819585554865 0.722213851250382 ICA1L other 1 1 1 -0.273203025167605 0.355819585554865 1.39990791036447e-07 396.718959840293 75.7437117330661 5.23764878645502 2.959431017624e-07 -256.481668475865 182.676421504451 -1.40402174710662 0.16128517131071 SNHG16 other 0.00153233919868495 1 0.00361405715872243 5.23764878645502 -1.40402174710662 0.00123555445526082 -27.6508851753962 7.86749442680112 -3.51457321421185 0.000504807708797274 -2.32927204381401 17.0857153773358 -0.13632862261675 0.891648306987954 CTLA4 other 1 1 1 -3.51457321421185 -0.13632862261675 0.0194160304023342 -18.5354270975572 6.61928967077117 -2.80021392316523 0.00542225478785807 -8.83272644515251 14.3718302554542 -0.614586053978784 0.539271789150258 ICOS other 1 1 1 -2.80021392316523 -0.614586053978784 3.356318604374e-14 219.298615194338 46.5128161542896 4.71479977619274 3.62565823270182e-06 -204.546115132387 64.9858810630259 -3.14754700230978 0.00180244724552746 RYBP other 4.54814734078721e-10 1 0.0418799782459387 4.71479977619274 -3.14754700230978 2.34417113974068e-22 220.182569290971 48.9436535012175 4.49869500006765 9.59868737566148e-06 -397.288688163033 68.3821515917122 -5.80983018105536 1.51794699735745e-08 PPP4R2 essential 3.45272967172405e-18 0.000230469892608782 0.107918042164562 4.49869500006765 -5.80983018105536 0.359344402293622 -2.91001364721938 2.41127701231378 -1.20683506389298 0.228387036139351 -10.1719850683364 9.90539829496237 -1.02691328156987 0.305236908168426 CD200R1 other 1 1 1 -1.20683506389298 -1.02691328156987 9.57307343997474e-13 70.8894219833958 9.36271722499555 7.57145818674765 3.98212673201518e-13 0.311916731892367 38.4615466257418 0.008109833307733 0.99353441356797 GTPBP8 other 1.26201827159187e-08 1 5.61479869214141e-09 7.57145818674765 0.008109833307733 4.77163044555155e-18 236.789505856931 25.6239226396965 9.24095460271559 3.51354435266809e-18 -12.4025377807213 105.261717475565 -0.117825721241917 0.906279670506727 NEPRO other 6.80386785231195e-14 1 5.16877509721002e-14 9.24095460271559 -0.117825721241917 1.21693441003262e-17 131.011223416354 14.239332463383 9.20065766799491 4.72822900856003e-18 15.190416340538 58.4944238193743 0.259689990065459 0.795269910194639 SPICE1 other 1.72853363601034e-13 1 6.95096946548411e-14 9.20065766799491 0.259689990065459 3.53697113252447e-07 32.9078571428572 5.9813613249965 5.50173369485858 7.71236125280232e-08 8.57244686109735 24.7547689549242 0.346294763514329 0.72934878430795 CCDC191 other 0.0037859739002542 1 0.000964970639950626 5.50173369485858 0.346294763514329 0.214026119025483 5.56898265610294 3.16664434780388 1.75863849692029 0.0796007620772951 4.74688273123066 5.83512865231501 0.813500955004205 0.416539579404317 NKX6-1 other 1 1 1 1.75863849692029 0.813500955004205 1.98791432673108e-13 210.242681531249 49.4124818912945 4.25484965506843 2.75521447624427e-05 -395.457159732732 91.0516487479403 -4.34321799957167 1.89045274379271e-05 CDS1 other 2.6574438719741e-09 0.276239027001575 0.299794887160139 4.25484965506843 -4.34321799957167 2.32368076479122e-09 321.062832297771 60.1836905522684 5.33471492611331 1.8244529561549e-07 -123.891471364011 110.801852604993 -1.1181353781663 0.264355810115739 WDFY3 other 2.77261588854889e-05 1 0.00224754359668723 5.33471492611331 -1.1181353781663 1.98794007163187e-08 58.3178961651841 11.4120128884993 5.11021997039234 5.56249873366491e-07 -34.5033343424389 24.726328826707 -1.39540869913417 0.163866286730117 COX18 other 0.000227698655804714 1 0.00671059847229335 5.11021997039234 -1.39540869913417 0.000841933841236838 496.50399034981 210.831039857186 2.35498525590034 0.0191288380869972 -644.181118307432 383.200367098495 -1.6810555876682 0.0937308923130601 PTPN13 other 1 1 1 2.35498525590034 -1.6810555876682 0.798520820516739 -8.97145090057308 14.6537031974851 -0.612230968490802 0.540822464088055 1.44000974753035 31.7500766367984 0.0453545282426618 0.963853192262279 ALB other 1 1 1 -0.612230968490802 0.0453545282426618 1.50308552444593e-20 157.48298668523 47.55646038506 3.31149512411365 0.0010347838237338 -425.451374431273 66.7442956027978 -6.37434810853616 6.45484373241741e-10 THOC7 essential 2.18999560911772e-16 9.8584828325211e-06 1 3.31149512411365 -6.37434810853616 5.04853135648655e-12 60.4431729179356 33.7397791906392 1.79145134816724 0.0741716804052968 -244.192163766962 47.3529311819977 -5.15685423629693 4.4245312777844e-07 ATXN7 other 6.54542090368482e-08 0.0066553799480433 1 1.79145134816724 -5.15685423629693 5.06177407909072e-28 165.154816813156 47.985599257784 3.44175793087268 0.000655212510597817 -548.618918038421 67.3465812132875 -8.14620294237265 8.66862702783593e-15 PSMD6 essential 7.6164514568078e-24 1.33054756250254e-10 1 3.44175793087268 -8.14620294237265 5.82305383122788e-05 130.490166217039 33.7659365285725 3.86455047993765 0.000134917604889451 8.95816681505477 47.3896423476536 0.1890321676061 0.850188192415509 PRICKLE2 other 0.515456725140292 1 1 3.86455047993765 0.1890321676061 0.951298353125622 -19.035625881371 60.6266211119906 -0.313981309402153 0.753741106668465 -16.9394204144286 84.9162584284472 -0.199483829456549 0.842011785574993 ADAMTS9 other 1 1 1 -0.313981309402153 -0.199483829456549 0.588822899064189 -14.2841287565211 23.4993409500636 -0.607852313257425 0.543716570068142 -43.6910170764103 43.3804385319178 -1.00715941458877 0.314619127562413 PPM1K other 1 1 1 -0.607852313257425 -1.00715941458877 6.06563837323328e-23 705.182216739375 64.4934780695829 10.9341632339714 8.13897805637151e-24 469.200635451374 371.488107025757 1.26303003131899 0.207509527637587 GMPS essential 8.96743977098808e-19 1 1.22288145296982e-19 10.9341632339714 1.26303003131899 5.42052553254102e-05 319.392385069931 71.4333568270944 4.47119384075741 1.08803577667093e-05 -191.55086117546 413.980316575309 -0.46270523864536 0.643896149361737 TIPARP other 0.481613693566269 1 0.121740323051711 4.47119384075741 -0.46270523864536 1.30450294922318e-08 310.045927430843 51.0569794542984 6.07254739204399 3.63237297957652e-09 -348.930156626157 295.892359770113 -1.17924692917807 0.239192602524893 CCNL1 essential 0.000150526595310862 1 4.76022478973503e-05 6.07254739204399 -1.17924692917807 0.097245971581651 22.5203585099662 11.5067581023945 1.95714190822173 0.0512165330164543 -60.0495278090919 66.685531431976 -0.900488104684998 0.368550661119007 PTX3 other 1 1 1 1.95714190822173 -0.900488104684998 0.978892323469057 0.481979546985214 2.34073329928179 0.205909638288608 0.836992432277273 0.411184467051854 3.48793619267785 0.117887611566704 0.906230670295303 DCLK3 other 1 1 1 0.205909638288608 0.117887611566704 1.92947049629509e-14 301.155162701748 74.2660988355354 4.05508256692822 6.30018265783802e-05 -425.44151189107 107.195773696475 -3.96882728880439 8.92134935956288e-05 SLMAP other 2.62716702775539e-10 1 0.666307317892949 4.05508256692822 -3.96882728880439 0.0124143772485728 207.08157405064 153.42305694641 1.34974219763443 0.178055711918436 -453.584720146315 293.919209301907 -1.54322924732832 0.123766567405445 RPL9 essential 1 1 1 1.34974219763443 -1.54322924732832 2.91652151712766e-05 53.6370246792872 81.892173711042 0.65497131470153 0.512958220984513 -555.630170874455 156.823803042905 -3.54302191436107 0.000454638406738259 SMIM14 other 0.266890884032352 1 1 0.65497131470153 -3.54302191436107 9.00115791891757e-16 94.091151795533 25.9946734321394 3.6196320004236 0.000342815216716 -180.164448448721 37.5207419567873 -4.80172936495277 2.41956859696357e-06 RPP14 essential 1.25143098546711e-11 0.036066089506339 1 3.6196320004236 -4.80172936495277 4.00363803306619e-07 36.3454913240981 21.7596597575734 1.6703152406346 0.0958347777134189 -111.89820601788 31.4079182784412 -3.56273870257388 0.000422840753259159 ABHD6 other 0.00426067159478904 1 1 1.6703152406346 -3.56273870257388 0.118727504302097 -87.1258680240529 54.2273346213217 -1.60667804590557 0.109111273790984 -153.965490998007 78.2717980528797 -1.96706214534626 0.0500396959892064 DNASE1L3 other 1 1 1 -1.60667804590557 -1.96706214534626 0.0641669290186828 48.9882354240595 20.8489159733522 2.34967781954099 0.0193969958055359 41.597756483587 30.0933496378419 1.38229067166649 0.167846492378946 C3orf67 other 1 1 1 2.34967781954099 1.38229067166649 0.00318322285064397 80.8399192404362 93.2222044775361 0.867174507334423 0.386498223614634 -417.560293864826 178.520852136561 -2.33900011605036 0.0199524077126676 RBM47 other 1 1 1 0.867174507334423 -2.33900011605036 3.71075438467853e-10 236.569854333246 54.347551141487 4.35290734107533 1.81163727582347e-05 -221.069964551013 104.075753150115 -2.12412553221834 0.0344286321044116 APBB2 other 4.56163036508531e-06 1 0.199696776914021 4.35290734107533 -2.12412553221834 5.04398164673722e-11 112.926904701983 27.0935385426748 4.16803823997047 3.95872370121856e-05 -162.192961997084 47.3351915519543 -3.42647735605048 0.000691281333254736 IL17RE other 6.37206201432313e-07 1 0.425998257488129 4.16803823997047 -3.42647735605048 5.96784321422141e-25 143.737696675288 25.9498903165351 5.53904833207325 6.35318109836827e-08 -305.272231467177 45.3371207659214 -6.73338373301909 7.68819769884219e-11 IL17RC other 8.89566709511843e-21 1.17606360199189e-06 0.000797070100601283 5.53904833207325 -6.73338373301909 1.95717459303749e-17 203.549767634603 24.1832300344896 8.41698016949371 1.3096250821313e-15 1.28736613496711 42.2505839990041 0.0304697832105102 0.975711386303782 CRELD1 other 2.77390355071204e-13 1 1.89607519390969e-11 8.41698016949371 0.0304697832105102 5.02370517164195e-12 38.9206714079913 6.90334997892269 5.63793977225896 3.78219390872811e-08 -24.539806947964 12.0608606767178 -2.03466465667209 0.0427087030741062 PRRT3 other 6.51373612555096e-08 1 0.000478636639149542 5.63793977225896 -2.03466465667209 5.38222419173022e-20 15.3573957718611 2.27642178993441 6.74628745857486 7.11302564605849e-11 -15.36039851425 3.97714242124056 -3.8621695899587 0.000136021110330158 FANCD2OS other 7.80745441252385e-16 1 9.68794092993166e-07 6.74628745857486 -3.8621695899587 3.46396820432319e-08 70.380368417813 11.8181215962593 5.95529228943542 6.87018493755406e-09 -18.0471135198231 60.5363955460487 -0.298120054176254 0.765806224390279 PCOLCE2 other 0.000391566965816694 1 8.92849234484526e-05 5.95529228943542 -0.298120054176254 1.06757397600763e-14 570.6958516177 68.038481442492 8.38783934500461 1.63599907433505e-15 -44.4951410355015 348.515996506491 -0.127670297723831 0.89849059264791 U2SURP essential 1.46150877315444e-10 1 2.36696346074794e-11 8.38783934500461 -0.127670297723831 2.93843756434512e-43 208.345249485791 23.6680843963389 8.80279307766953 8.62014549916419e-17 -337.892444693069 40.3118221464582 -8.38196902798045 1.68797887365119e-15 MTMR14 other 4.49463409842229e-39 2.59121636894194e-11 1.25733442250809e-12 8.80279307766953 -8.38196902798045 6.16573065072888e-08 66.3252539157143 11.2077681671885 5.91779317044458 8.60986364951946e-09 -20.8267000432271 74.0464494746742 -0.28126534345648 0.778693930787447 TTC14 other 0.000687663939475791 1 0.000111420245488431 5.91779317044458 -0.28126534345648 0.650329003140067 -15.4020233640145 19.5236437490316 -0.788890821918345 0.430763564471704 -30.9854903501596 42.3017429046663 -0.732487321385086 0.464410714181403 CXCL3 other 1 1 1 -0.788890821918345 -0.732487321385086 0.950511439915568 16.0980018636244 93.9833758381289 0.171285631315804 0.864108117807755 -39.2192238904671 203.633125717855 -0.192597465428133 0.847397169363977 CXCL5 other 1 1 1 0.171285631315804 -0.192597465428133 0.546371470525023 -2.43484505935475 7.36996120794727 -0.330374202883073 0.741334782131288 -17.5527558243641 15.9684436083512 -1.09921519309398 0.272505699460862 PPBP other 1 1 1 -0.330374202883073 -1.09921519309398 0.00420216602638458 26.9067747483143 16.5748868103798 1.62334591217022 0.105506322267535 -77.9827926030411 35.9126917874339 -2.17145495705582 0.0306357968969326 MTHFD2L other 1 1 1 1.62334591217022 -2.17145495705582 0.789534775411232 -163.85227714333 272.880712902489 -0.600453859125913 0.54863148420392 62.8189610936124 591.24873969367 0.106247940800955 0.915452627170159 CXCL1 other 1 1 1 -0.600453859125913 0.106247940800955 7.08576242034445e-07 47.472767060467 11.6008247634038 4.0921889631697 5.42620242959288e-05 -46.4033022221058 24.2760296226498 -1.91148647218699 0.0568436060081881 RCHY1 other 0.00740887318671215 1 0.576805318265723 4.0921889631697 -1.91148647218699 3.15466331234286e-05 -23.4526926040505 13.2568630592073 -1.76909820213929 0.0778389831044232 338.19171810667 80.6053216846251 4.1956500022402 3.53653540986568e-05 CPA3 other 0.287452921020681 0.512939095846918 1 -1.76909820213929 4.1956500022402 3.43227403171538e-10 252.688609404498 37.0623181059616 6.81793860497495 4.67455259787598e-11 177.127855807661 225.34894265458 0.786015917009057 0.43244529977748 GYG1 other 4.22375642342894e-06 1 6.38730866973774e-07 6.81793860497495 0.786015917009057 1.93424630728024e-08 262.139823509878 55.0159413263289 4.76479756939878 2.88315754051298e-06 1377.85389318047 338.556525788949 4.06978979350528 5.94639743175866e-05 HPS3 other 0.000221722654203534 0.855270342609849 0.0334849916755177 4.76479756939878 4.06978979350528 0.919807788351697 -0.592927874224932 3.3638027666606 -0.176267134358047 0.860196633908111 -7.79545437224065 20.7001343731413 -0.37658955404441 0.706730592482971 TM4SF18 other 1 1 1 -0.176267134358047 -0.37658955404441 1.69603299031306e-13 503.784819718819 63.394946464468 7.94676623003671 3.30156522311137e-14 -36.7644696004069 260.306639630803 -0.141235235691838 0.887772979264448 TOPBP1 essential 2.26980095093597e-09 1 4.72321920818313e-10 7.94676623003671 -0.141235235691838 2.31723705888125e-20 407.498789173857 40.033706128277 10.178892452978 2.88513249933869e-21 53.7687193052704 163.874718126056 0.328108691323029 0.743044063179991 RYK other 3.37111647326044e-16 1 4.30548322876312e-17 10.178892452978 0.328108691323029 4.62899993516228e-07 108.725235994381 44.9310838016197 2.41982224320307 0.0160849416748438 -191.238504259812 64.3875898689436 -2.97011434422479 0.00320203173049604 SNRK other 0.00490396253131092 1 1 2.41982224320307 -2.97011434422479 0.0392447198713815 33.6797901853529 14.4124713396198 2.33685045345188 0.0200635570424996 -37.9533087527369 51.133071492608 -0.742245823394816 0.45848287171529 ZNF513 other 1 1 1 2.33685045345188 -0.742245823394816 9.35938207495764e-10 109.830217727543 18.5304578047866 5.92701048644211 7.97968736349075e-09 -149.91661154075 65.7193419143579 -2.28116422310062 0.0231954939739097 SLC4A1AP other 1.13276601253212e-05 1 0.000103424727918204 5.92701048644211 -2.28116422310062 0.00121941683630149 37.4173420582986 10.2743391028658 3.64182471336398 0.000315647151497243 -7.44704818560384 36.4385387322098 -0.204372854804439 0.838192062134997 PLB1 other 1 1 1 3.64182471336398 -0.204372854804439 2.00358485836769e-08 324.977668922147 55.1824580227921 5.88914812000439 9.81634401194434e-09 -158.075574146459 192.535567337713 -0.821020117645017 0.412246023105945 SPDYA other 0.000229390430434517 1 0.000126827164634321 5.88914812000439 -0.821020117645017 1.78403484227637e-13 96.1221625218743 28.8372356478618 3.33326549380962 0.000958987737314666 -185.22329299452 41.3246230615446 -4.48215323630825 1.03050542965694e-05 KIAA1143 other 2.38668181199733e-09 0.151659484082612 1 3.33326549380962 -4.48215323630825 1.43443704181672e-11 72.7007307815546 30.4808952115247 2.38512452725033 0.0176550985322801 -204.438727725334 43.6800364839441 -4.68036989393271 4.23434562710565e-06 KIF15 other 1.83708351945468e-07 0.0628715638712647 1 2.38512452725033 -4.68036989393271 6.96620214645533e-15 430.533586487138 52.5558019472264 8.19193258471169 6.22645818400796e-15 -200.411449256237 183.370975258447 -1.09292895985187 0.275247079860486 WDR43 essential 9.56180906622458e-11 1 8.96547713915307e-11 8.19193258471169 -1.09292895985187 3.83976264394211e-07 179.037469499421 94.2155378935453 1.90029663367964 0.0582927932490457 -467.636059284088 135.013689853456 -3.46361957659006 0.000605523004447801 ZDHHC3 other 0.00409510685976426 1 1 1.90029663367964 -3.46361957659006 1.82306545498627e-09 1117.45888891628 293.673183342491 3.80511041627203 0.000169801744594767 -1074.71212998792 420.842474400356 -2.55371592784032 0.01112124792112 CDCP1 other 2.18093320380008e-05 1 1 3.80511041627203 -2.55371592784032 0.628197681120714 27.3838143593031 28.4795647426048 0.96152503055419 0.337014228060145 17.6867621324527 40.8120699333489 0.433370867033635 0.66503734327816 CLEC3B other 1 1 1 0.96152503055419 0.433370867033635 0.077375000663034 11.6659354743302 6.98359776962332 1.67047643051175 0.095802877724777 21.8706775441796 10.0077049328591 2.18538393077216 0.0295854150773818 SLC6A20 other 1 1 1 1.67047643051175 2.18538393077216 1.06977608618565e-07 45.6739025953222 25.0191543049356 1.82555741247865 0.0688488706806539 -134.379392288796 35.8531980525237 -3.74804479343615 0.000211411280775961 LZTFL1 other 0.00117846533654212 1 1 1.82555741247865 -3.74804479343615 0.0269751531599563 286.605661400439 138.648020746369 2.06714571082649 0.0395242202185572 -80.2990699890735 198.686769617522 -0.404149054029372 0.686373083849327 FYCO1 other 1 1 1 2.06714571082649 -0.404149054029372 0.441488219817337 -15.6712743173713 24.1525637226203 -0.648845170117249 0.516903831762365 -44.3592579857809 34.6531870780884 -1.28009172391043 0.20144006167159 CCR1 other 1 1 1 -0.648845170117249 -1.28009172391043 0.506109908622932 1.14575014378017 11.4410864747508 0.100143473813323 0.920293131738095 -15.3164371982407 16.3563944437416 -0.936418918663408 0.349763697030332 RTP3 other 1 1 1 0.100143473813323 -0.936418918663408 0.346083530101493 40.158885821123 33.0217390761093 1.21613479316047 0.224829898155796 62.609707875471 47.2085051309713 1.32623788238522 0.185706706475381 LRRC2 other 1 1 1 1.21613479316047 1.32623788238522 3.38021553665511e-17 35.3106542960303 20.6609645724479 1.70905158721961 0.0884139845169936 -203.101424381721 29.8249422962105 -6.80978431960038 4.86632930028188e-11 ELP6 essential 4.77455444552534e-13 7.44743036115138e-07 1 1.70905158721961 -6.80978431960038 0.436459814134655 19.8578912840272 18.5185033694324 1.07232700655528 0.284383735704235 -37.1866709640043 72.5617268940953 -0.512483268462983 0.608667479984858 FBXO40 other 1 1 1 1.07232700655528 -0.512483268462983 1.20381795882796e-08 702.535247643806 118.752775993342 5.91594800009723 8.47844248121183e-09 -376.783194883128 467.515963061557 -0.805925839228549 0.420884096609796 DTX3L other 0.000139137279681335 1 0.000109761916361768 5.91594800009723 -0.805925839228549 2.12260622804881e-17 319.362063468229 34.6994012158575 9.20367649809132 4.62433128630157e-18 43.0654032264146 138.75952819726 0.310359971570335 0.756489269021187 ZNF148 other 3.00709624327675e-13 1 6.79869185712057e-14 9.20367649809132 0.310359971570335 1.92435553047181e-09 71.2003382819632 11.0954756862367 6.41706045737929 5.03877855176864e-10 104.018442646973 51.6697997627448 2.01313810242348 0.0449424633972331 NMNAT3 other 2.30056703667905e-05 1 6.75246713722515e-06 6.41706045737929 2.01313810242348 1.79596742672302e-07 71.8926175714338 29.0330125878144 2.47623691664737 0.0137976187964038 -313.745267075852 68.9153984728352 -4.55261485863023 7.55434883084448e-06 SMIM12 other 0.00195329417330395 0.111502188743265 1 2.47623691664737 -4.55261485863023 0.000235654084050581 41.4785074441174 13.1539987938411 3.15330023167846 0.00176836185634657 -62.5808070335504 31.2235275497808 -2.00428369068087 0.0458873182227389 ZMYM6 other 1 1 1 3.15330023167846 -2.00428369068087 1.20700075773635e-08 177.86465591293 29.0799641526186 6.1163987334872 2.7894177885813e-09 5.18162168635099 116.914799171919 0.0443196389426425 0.964677260203793 TPRA1 other 0.000139481007564012 1 3.66911439354374e-05 6.1163987334872 0.0443196389426425 1.03520478531233e-26 509.867661400173 42.7687346537212 11.9215044711596 2.62074263125112e-27 293.911376439899 279.771017909285 1.05054261387146 0.294271442520797 YEATS2 essential 1.55197901414025e-22 1 3.96387322976732e-23 11.9215044711596 1.05054261387146 3.36385128414806e-07 147.418754795744 30.6393971055209 4.81141173529099 2.31881465265063e-06 -137.93260076374 72.7750997046858 -1.89532685387525 0.0589557896198584 MEAF6 other 0.00360571219147831 1 0.0270814363283068 4.81141173529099 -1.89532685387525 1.72762494824117e-10 72.1198113692956 12.6812217564632 5.6871343120026 2.92848234843874e-08 -86.0887946829049 30.1206050016416 -2.85813630497173 0.00454249325895361 SNIP1 essential 2.1462284732e-06 1 0.000372327245780501 5.6871343120026 -2.85813630497173 0.570415702411047 -13.4157906628697 19.2215449757618 -0.697955896874413 0.485714802664374 -41.7774922764765 45.6552668863418 -0.915064024934538 0.360851361633149 DNALI1 other 1 1 1 -0.697955896874413 -0.915064024934538 5.38971619333171e-15 267.293940954915 31.869972831221 8.38701502415666 1.64541565594045e-15 226.149860515524 209.26826562284 1.0806696363753 0.280662978076307 POLR2H essential 7.4108597658311e-11 1 2.38042282944905e-11 8.38701502415666 1.0806696363753 0.0397089896630418 17.4884212947627 6.86736590930365 2.5465981463242 0.0113459286599185 17.9633767418562 27.4039050363364 0.655504269119221 0.512614110881483 KLF15 other 1 1 1 2.5465981463242 0.655504269119221 0.0992746342567632 7.01613271071886 3.57271705413719 1.96380866561885 0.0504231879779378 -23.8930224760628 23.4975664672748 -1.01682965805581 0.310007465543519 CAMK2N2 other 1 1 1 1.96380866561885 -1.01682965805581 0.256428644572859 50.1907943225011 30.73672299855 1.63292600596586 0.103477391799911 -68.9278334437363 193.372378338913 -0.356451288626809 0.721739755620584 LIPH other 1 1 1 1.63292600596586 -0.356451288626809 1.64501678184511e-22 264.857245756989 25.3931445761231 10.430265734242 4.3035915698255e-22 384.216016521857 159.754595843559 2.40503889414301 0.0167435868376276 TMEM41A other 2.42541274315243e-18 1 6.43860334761593e-18 10.430265734242 2.40503889414301 7.40193964518014e-25 2104.93883933389 183.952785828138 11.4428212101146 1.20114014326553e-25 557.646917463833 740.149257403222 0.753424950286798 0.451748560077145 RPN1 essential 1.10259292954603e-20 1 1.8121601341447e-21 11.4428212101146 0.753424950286798 2.40061479376333e-33 354.625668366658 25.8764647856925 13.7045640238591 6.8378798679353e-34 205.280857091407 162.795283636728 1.26097545644802 0.208244934551813 SENP2 other 3.64389319545336e-29 1 1.0418877554773e-29 13.7045640238591 1.26097545644802 0.00175707758685963 48.2663667736353 19.1762912175317 2.51698131959471 0.0123279918699693 140.417492805114 48.004828881566 2.92507016641058 0.0036913704256665 HEYL other 1 1 1 2.51698131959471 2.92507016641058 1.01485850558531e-13 184.761526438333 22.9444353680372 8.05256365975846 1.61359570372502e-14 50.4483330580052 92.0643458054189 0.547968191341189 0.584095772723959 IFT122 other 1.36417280320777e-09 1 2.3143803178528e-10 8.05256365975846 0.547968191341189 2.89748909034952e-09 189.756793655101 29.534382202349 6.42494541971522 4.77714590898897e-10 -211.795643420685 183.641661600846 -1.15330933936457 0.249644151470198 RFC4 essential 3.44395553278944e-05 1 6.40758580772691e-06 6.42494541971522 -1.15330933936457 1.57392591394633e-05 108.370869974427 25.2137262344542 4.29809021350996 2.29123546917242e-05 286.641758301434 156.73088508731 1.82887857834629 0.0683512950205374 RPL39L other 0.147649989987305 1 0.250661160327463 4.29809021350996 1.82887857834629 6.1988376551079e-12 340.536254673557 97.8231020783344 3.48114348695326 0.000569067375149512 -522.020367945795 138.519846475211 -3.76856011054858 0.000195661337880998 BAP1 other 8.01819650688206e-08 1 1 3.48114348695326 -3.76856011054858 1.98212643888285e-05 2757.78157732595 843.736967228731 3.26853235598285 0.00119861312701952 -1378.79696277771 1217.16704177595 -1.13279189745881 0.258149698927263 TKT essential 0.184060261114662 1 1 3.26853235598285 -1.13279189745881 5.12627441716639e-13 191.712877387555 50.2364870687782 3.81620787148358 0.000162665916654912 -272.109854662752 72.4706854501779 -3.75475756814556 0.000206058974483966 PRKCD other 6.79385148507061e-09 1 1 3.81620787148358 -3.75475756814556 2.69069922047345e-17 141.328295458665 22.6498768904629 6.23969375825494 1.38872303733214e-09 -79.9397576362281 32.6745001370557 -2.44654875517344 0.0149609181622592 RFT1 essential 3.8059940473597e-13 1 1.84075238598376e-05 6.23969375825494 -2.44654875517344 8.79347631352825e-14 85.965695335436 23.2902449864037 3.69106015783092 0.000262432419551627 -138.784562101452 33.5982891509992 -4.13070324735046 4.62114525231283e-05 SFMBT1 other 1.1833381075115e-09 0.667385797339019 1 3.69106015783092 -4.13070324735046 2.0431904153781e-19 429.624170925303 85.4303122546412 5.02894300145746 8.23170049763766e-07 -558.170180173841 123.240967841567 -4.52909604614109 8.37107606895625e-06 GNL3 essential 2.94975400268136e-15 0.123423145560691 0.00985087598552299 5.02894300145746 -4.52909604614109 2.0824879196549e-12 189.39413214454 73.3274969402717 2.58285281848376 0.0102423517492122 -496.147571565324 105.781559891555 -4.69030303650241 4.04649668862469e-06 PBRM1 other 2.72326945253272e-08 0.0601026153161425 1 2.58285281848376 -4.69030303650241 1.71860803899513e-08 27.5072859544362 8.9693561959034 3.06680717697439 0.00234933534496815 -46.3530613314576 16.559216334155 -2.79923037395494 0.00543536810020938 UVSSA other 0.000197416505439371 1 1 3.06680717697439 -2.79923037395494 2.15012321612834e-14 238.14078992339 80.9029144494422 2.94353783845709 0.00348214419376425 -580.85176468606 116.907285854008 -4.96848216467379 1.10092371893834e-06 FAM208A other 2.92545764786423e-10 0.0164830299199448 1 2.94353783845709 -4.96848216467379 4.10961993186828e-09 72.8228868082612 57.7320547619752 1.26139433471586 0.208085561877692 -383.677870738373 83.4246562676708 -4.59909441529288 6.12043055597149e-06 ARHGEF3 other 4.85633787348875e-05 0.0905762517978221 1 1.26139433471586 -4.59909441529288 5.76455985721316e-10 117.082478285297 61.1385929293661 1.91503390371713 0.0563822466169962 -492.341641662161 112.818366439897 -4.36402030270888 1.72689839118574e-05 SLBP essential 7.03506884974294e-06 0.252731579550033 1 1.91503390371713 -4.36402030270888 1.51408583042685e-09 343.343380042061 123.977272386707 2.76940582279558 0.00594357421357106 -778.825831777688 229.365723773333 -3.39556329064821 0.000771172952531747 LRPAP1 other 1.81644877076309e-05 1 1 2.76940582279558 -3.39556329064821 4.97034357162655e-07 33.0302264959741 6.00519455598172 5.5002758342064 7.77083991235526e-08 14.6487261773736 36.859813414073 0.397417263424907 0.691324742725066 SLC51A other 0.00525613832699507 1 0.000972054364636519 5.5002758342064 0.397417263424907 7.85866152857206e-28 537.479825445559 43.7018127373195 12.2987993353093 9.89055485836867e-29 337.088477012492 268.241211560717 1.25666177486747 0.209792675982091 UBXN7 other 1.18202128051252e-23 1 1.49960592762586e-24 12.2987993353093 1.25666177486747 6.16880506179991e-23 524.639445442083 47.8438981317148 10.9656500813906 5.75614469402094e-24 171.265161482167 293.665282897504 0.583198530627614 0.560170437151809 RNF168 essential 9.11934452285881e-19 1 8.65263670405228e-20 10.9656500813906 0.583198530627614 6.90455615823347e-15 297.715377396745 35.0336391752963 8.49798606154159 7.42465349828754e-16 84.3686677865949 215.036064390469 0.392346595561737 0.695063332846237 PIGX other 9.47857469402291e-11 1 1.07672325032166e-11 8.49798606154159 0.392346595561737 1.18775444665577e-07 328.576020348873 59.5289182731891 5.51960341091665 7.04455115337074e-08 692.802038383318 371.3339000647 1.86571179809494 0.0629993940147875 MELTF other 0.00130474825965136 1 0.000882541368494286 5.51960341091665 1.86571179809494 0.0153191893723639 77.1473200475218 265.289568810974 0.290804197063969 0.771390048650936 -1091.13849133453 492.233506459829 -2.21670909642471 0.0273479284685392 S100P other 1 1 1 0.290804197063969 -2.21670909642471 0.464885925935613 44.6165106805818 44.5851378253375 1.00070366173067 0.317726195253016 -2.39643711221776 82.6839156668964 -0.028983111078969 0.976896127378865 ABLIM2 other 1 1 1 1.00070366173067 -0.028983111078969 0.00271217758834426 4.1632782151661 9.40095978355012 0.442856720060758 0.658171417694713 -77.7357241210589 23.6273558798105 -3.29007293564676 0.00111439877030064 EXO5 other 1 1 1 0.442856720060758 -3.29007293564676 0.610960356641649 9.92934365585976 10.023674562448 0.990589189024393 0.322636990753329 2.99033205515218 31.1898124816337 0.0958752816136056 0.923679827289344 CLDN19 other 1 1 1 0.990589189024393 0.0958752816136056 4.00292044133325e-11 35.7231375406251 5.44701959617256 6.55829062295399 2.19390662119402e-10 -30.0060781594191 16.9490259016266 -1.77037183927717 0.0776202656438857 C1orf50 other 5.07450224347816e-07 1 2.96067698530133e-06 6.55829062295399 -1.77037183927717 0.0760607249946162 29.5163381774516 13.0237633870843 2.26634478070471 0.0240997854970488 6.22583505899932 40.7562371133141 0.152757847631755 0.878685816385084 ERMAP other 1 1 1 2.26634478070471 0.152757847631755 0.000124752794753762 23.6107213896819 5.99695874392593 3.93711586120153 0.000101294047354696 -19.2746024841422 18.76673164752 -1.02706229545779 0.305169279006867 ZNF691 other 1 1 1 3.93711586120153 -1.02706229545779 9.12526651369332e-06 103.83730123728 32.1949722544337 3.22526450455258 0.00138900567524971 -127.530390176903 58.4475608452092 -2.18196257179407 0.0298416676590821 AIMP1 other 0.0874315036232917 1 1 3.22526450455258 -2.18196257179407 5.24120645854915e-12 341.334797004704 56.9159738408899 5.99717045971864 5.45336688243773e-09 -210.308499629922 103.312385189605 -2.03565622111959 0.0426135444821664 SGMS2 other 6.79155532898799e-08 1 7.10900906794583e-05 5.99717045971864 -2.03565622111959 2.34978632579756e-05 207.397851829737 75.1281931557004 2.76058618100814 0.00610254603215135 -332.094136334347 135.668457569582 -2.44783601349651 0.014908579973134 METAP1 essential 0.216861780007857 1 1 2.76058618100814 -2.44783601349651 3.70359387612239e-07 128.281147950098 27.4041004736984 4.68109318432905 4.22038856072233e-06 -49.1191089865574 49.487041897086 -0.992565065592448 0.321671888504671 DNAJB14 other 0.00395617897847393 1 0.0485457307579317 4.68109318432905 -0.992565065592448 0.0213428338296052 369.434836184148 304.432577003921 1.21351939342349 0.225826242610189 -1019.77412974091 549.75231562482 -1.85497013974718 0.0645200793934338 H2AFZ essential 1 1 1 1.21351939342349 -1.85497013974718 0.361342015747065 -11.4027248656816 9.54835145631061 -1.19420875088813 0.233280781728738 4.59887911528035 17.242662973742 0.266715131084087 0.789860292127819 EMCN other 1 1 1 -1.19420875088813 0.266715131084087 4.35253842960754e-06 19.9977261314972 5.83392222752989 3.42783557126101 0.00068795509831006 -22.5772972960664 10.5997014567955 -2.12999369728399 0.0339347723932481 SLC9B1 other 0.0428594459163454 1 1 3.42783557126101 -2.12999369728399 0.00219371920312643 45.0847593878205 13.4834037620814 3.34372241485564 0.00092474570177231 5.62064768246467 24.4981076067601 0.229431912565919 0.818679808619206 SLC9B2 other 1 1 1 3.34372241485564 0.229431912565919 0.0411928211985976 29.5743134841427 16.0513792456294 1.84247802207997 0.066330211801421 -26.4069564207466 29.1638834625867 -0.905467766479835 0.365898861127587 BDH2 other 1 1 1 1.84247802207997 -0.905467766479835 1.05340911604192e-14 223.466670381857 40.3470632663039 5.53861055281529 6.39550988523121e-08 -288.386760655255 72.5507043181519 -3.97496844952203 8.71612105551521e-05 PGRMC2 other 1.4425384435078e-10 1 0.000802252760003403 5.53861055281529 -3.97496844952203 9.34521865013361e-13 78.3609185870935 26.8379210837978 2.91978347884778 0.00375128831467324 -175.759109136364 38.6397273583854 -4.54866328393546 7.67241720439942e-06 CDC25A other 1.23226053120662e-08 0.113229533102527 1 2.91978347884778 -4.54866328393546 8.2607326094085e-07 11.1486812638972 28.4357212393792 0.392066062613456 0.695270387722229 -176.343902741399 40.6737882139898 -4.33556623281885 1.95013661372044e-05 ZNF589 other 0.00860272693943802 0.284875956532281 1 0.392066062613456 -4.33556623281885 4.87406161818922e-20 142.068816421484 161.448485909613 0.879963758229489 0.37953929742753 -1853.17170236843 230.932124705984 -8.02474625272614 1.94894851232502e-14 PLXNB1 other 7.07665006344893e-16 2.99124617671645e-10 1 0.879963758229489 -8.02474625272614 4.70310273592037e-17 88.4811182945448 41.7406048822114 2.11978524375081 0.0347936353650949 -382.506048592373 59.7047814827981 -6.40662337408569 5.31430732503517e-10 CCDC51 other 6.6323154781949e-13 8.11919873118873e-06 1 2.11978524375081 -6.40662337408569 1.51472691229454e-17 48.3227623426258 17.3612907316613 2.78336231386881 0.00569966106576636 -149.779720558251 24.833182756173 -6.03143471494885 4.48358377525932e-09 ATRIP essential 2.15045779738455e-13 6.82670465620984e-05 1 2.78336231386881 -6.03143471494885 2.27269568046533e-13 599.00926636649 317.997804946603 1.88368994077513 0.0605134830199838 -2514.67720705964 454.856596111228 -5.52850553022367 6.71157137930891e-08 SHISA5 other 3.03563962039754e-09 0.00101559498111702 1 1.88368994077513 -5.52850553022367 0.207842013074143 60.5446519211421 34.9451513986048 1.73256230114829 0.0841399956134452 61.545946661289 63.0523550597529 0.976108610106056 0.329750271204306 SPRY1 other 1 1 1 1.73256230114829 0.976108610106056 0.304536113058514 -4.3974746137258 7.92452314930054 -0.554919776354486 0.579338414795913 -16.959119363891 11.1905447831682 -1.51548648367856 0.130639486806634 BSN other 1 1 1 -0.554919776354486 -1.51548648367856 2.31546617596761e-31 410.987632327971 97.2939381405954 4.22418539307218 3.13283095988301e-05 -1158.09569451461 137.392768167915 -8.42908771660554 1.21512553044391e-15 APEH other 3.50584733703256e-27 1.86570373944358e-11 0.339567547741719 4.22418539307218 -8.42908771660554 0.12891588141708 24.4584024192156 14.4400060803763 1.69379446816537 0.0912804519047523 -11.4757189152927 25.9549895552161 -0.442139223014498 0.658688063633666 INTU other 1 1 1 1.69379446816537 -0.442139223014498 8.64505076290614e-13 166.784529338589 47.1068060278894 3.54056119278909 0.000458735961483364 -264.661170294443 66.5214565615398 -3.97858351236794 8.58529494484883e-05 RNF123 other 1.14062799765784e-08 1 1 3.54056119278909 -3.97858351236794 0.00331080037223245 160.373810062506 101.887392838737 1.57402997166037 0.116471744576951 -414.688415071359 183.136087493166 -2.26437301761639 0.0242221035425055 HSPA4L other 1 1 1 1.57402997166037 -2.26437301761639 0.000556516036067091 19.5914863117086 9.94475778584434 1.97003152149122 0.0496994576246636 -43.9773730367509 17.8750675743496 -2.46026331670252 0.0144132455775914 MFSD8 other 1 1 1 1.97003152149122 -2.46026331670252 0.00196670261207722 20.3739527368139 8.51779183605732 2.39192893286818 0.0173387663095802 -24.744516184951 15.310187330102 -1.61621250291952 0.1070368590682 ABHD18 other 1 1 1 2.39192893286818 -1.61621250291952 1.71672908207676e-12 31.2228740177631 12.079795128371 2.58471883719552 0.0101896403462395 -80.8697605689908 17.0583750982497 -4.74076575894315 3.21353845021484e-06 MON1A other 2.24977346206159e-08 0.0477981709084956 1 2.58471883719552 -4.74076575894315 4.13757796514406e-12 185.725309720334 79.5267029834084 2.3353829940502 0.0201430236445127 -541.728287308308 112.302925289845 -4.82381278947232 2.18549488501482e-06 MST1R other 5.37471377672213e-08 0.0325900997253411 1 2.3353829940502 -4.82381278947232 6.4649853071357e-09 138.419431168222 35.1035783828155 3.94317153820373 9.88854542431372e-05 -103.5267335266 49.8131461261386 -2.07830144404945 0.0384807680905283 RAD54L2 other 7.56985129612519e-05 1 1 3.94317153820373 -2.07830144404945 6.44882444535587e-16 76.7296873775754 49.8633080730266 1.53880057988134 0.124844290634355 -462.902295698505 70.7576938250341 -6.54207720284306 2.41421147662996e-10 TEX264 other 8.97998804015805e-12 3.69012224202889e-06 1 1.53880057988134 -6.54207720284306 1.77337677458662e-12 1231.39453589535 250.002282061027 4.92553318211217 1.35311630941244e-06 -840.788150823951 354.386833693787 -2.37251520340184 0.0182601426610913 DUSP7 other 2.32223688632119e-08 1 0.0160290158012998 4.92553318211217 -2.37251520340184 6.63610902226815e-14 51.4815046629532 29.5524311668313 1.74203957611225 0.0824653392565042 -244.650490884218 41.8915876400297 -5.84008639124578 1.28535103049479e-08 POC1A other 8.95211107103973e-10 0.000195231968021853 1 1.74203957611225 -5.84008639124578 1.83569098286043e-08 24.5561745008453 27.1291747945863 0.905157443482045 0.366065096689598 -179.293106608607 38.4565383840452 -4.66222687071055 4.60466853514732e-06 PPM1M other 0.000210645540283235 0.0683378857301213 1 0.905157443482045 -4.66222687071055 7.27402719957693e-18 539.958221192968 123.152442340032 4.38447026249066 1.58077976972667e-05 -833.126018204738 174.572822866822 -4.77236951618932 2.77675952728694e-06 WDR82 essential 1.03574873294776e-13 0.0413376190827206 0.174929089317953 4.38447026249066 -4.77236951618932 0.0172283531615435 208.852602439541 73.0414321012688 2.85937168030846 0.00452439430847828 104.189248171215 132.852775440906 0.784245928061615 0.433477774329844 PITX2 other 1 1 1 2.85937168030846 0.784245928061615 2.87751406727747e-05 337.27509088194 147.555572291809 2.28574960364722 0.0229265037890925 -800.240098255443 267.393599742235 -2.99274215623286 0.00298134546790384 C4orf3 other 0.263551513421944 1 1 2.28574960364722 -2.99274215623286 0.00474793247341203 -136.613518923 68.2498710135394 -2.0016670638967 0.0461697364544148 -392.586173623774 124.149293220253 -3.16221029891235 0.00171674686959939 PRSS12 other 1 1 1 -2.0016670638967 -3.16221029891235 0.0233410965642089 27.0504937093548 244.437011987048 0.11066447543872 0.911953115959554 -1026.62865188952 418.126658375113 -2.4553054231919 0.0146182975748278 HMGB2 other 1 1 1 0.11066447543872 -2.4553054231919 0.0264870607206067 9.03431602647358 13.3487011842131 0.676793637208545 0.499035158597805 -47.92888566997 22.8338899024779 -2.09902412049245 0.0366129807220473 SAP30 other 1 1 1 0.676793637208545 -2.09902412049245 0.59178002587188 6.04662100454182 6.96651470608274 0.86795496164851 0.386079738758349 10.2682002328886 11.9179770400634 0.86157241269815 0.389578229046214 HAND2 other 1 1 1 0.86795496164851 0.86157241269815 0.0704120339590613 82.9211952972283 55.2851435889145 1.4998820644079 0.134633977652483 -112.187747346928 99.7522793172627 -1.12466349756395 0.261577187264731 MAD2L1 essential 1 1 1 1.4998820644079 -1.12466349756395 1.59831528239353e-09 1658.64198200654 319.55828755325 5.1904207983658 3.74225135524777e-07 -1129.82162662902 576.586502066166 -1.95950065181958 0.0509247346853791 ANXA5 other 1.91558086594865e-05 1 0.00454870652230366 5.1904207983658 -1.95950065181958 0.146801415185971 14.721556952856 16.4104161195128 0.89708614611858 0.370349465240724 -33.5528090822344 28.0673580156092 -1.19543881057756 0.232803544909638 MAP9 other 1 1 1 0.89708614611858 -1.19543881057756 0.781595111204033 20.0806272913154 29.0466588598542 0.691323135931105 0.489865285873497 20.2601943846435 49.6796039441928 0.40781714780582 0.683681488086696 GUCY1A3 other 1 1 1 0.691323135931105 0.40781714780582 5.00877686635803e-11 42.0928896653541 14.2557409166789 2.95269743686955 0.00338693656574064 -112.964710304069 24.4077714092677 -4.62822714986489 5.3971731055087e-06 FBXO8 other 6.32909044833e-07 0.0799807082505334 1 2.95269743686955 -4.62822714986489 0.000568577828837287 9.42233766564702 15.7482936666648 0.59830848122878 0.550064068261078 -87.3287000245785 26.9632251419676 -3.2388076561603 0.00132837577665797 CEP44 other 1 1 1 0.59830848122878 -3.2388076561603 0.474893516923359 -34.3843078484696 59.4578932723114 -0.578296773667928 0.563476976397772 -123.785466222341 101.4695205637 -1.21992757563718 0.223404884734727 HPGD other 1 1 1 -0.578296773667928 -1.21992757563718 0.616005027912264 27.7572409097884 31.2251907912092 0.888937431812359 0.374712884920157 40.6611585867646 53.3067019920733 0.762777607078579 0.446165060109825 ASB5 other 1 1 1 0.888937431812359 0.762777607078579 0.00125559754554278 6.6981514731368 7.77834709972277 0.861127870389781 0.389818487733563 -38.5536621663646 13.3653764189119 -2.88459231958566 0.00418759938802644 TMEM144 other 1 1 1 0.861127870389781 -2.88459231958566 0.00688696826561712 291.781058096331 91.7816546090248 3.17907820837695 0.00162329682286829 225.830822255646 157.706559822189 1.43196847683613 0.153138094367669 FAM198B other 1 1 1 3.17907820837695 1.43196847683613 5.83680012761025e-10 404.64025763691 68.0124938908835 5.94949890068872 7.15388716310761e-09 -91.9053854629028 120.194117069314 -0.764641296128517 0.445057607199921 NAA15 other 7.1208961556845e-06 1 9.28646092642999e-05 5.94949890068872 -0.764641296128517 0.000290495099663664 -29.1359868557858 16.3902063348625 -1.77764612967761 0.0764297802976472 -118.186622216348 28.9788956362868 -4.07836874461003 5.75431681994061e-05 IL15 other 1 0.828218819894051 1 -1.77764612967761 -4.07836874461003 1.27042756565347e-05 63.6086663835651 26.8064109089508 2.3728900746771 0.0182438244018752 -129.486777940939 45.8207916600083 -2.82593934434252 0.00501245455073675 FAM160A1 other 0.120207856262132 1 1 2.3728900746771 -2.82593934434252 2.91770742819417e-13 81.1521786452849 27.1948004080955 2.98410642576833 0.00306369387970865 -251.694509476685 46.4829756345999 -5.41476757975312 1.20942876986704e-07 ARFIP1 other 3.88696983584028e-09 0.00182708404263814 1 2.98410642576833 -5.41476757975312 6.55116340489139e-21 311.709340821458 30.0675634960024 10.3669637502521 6.78941559798128e-22 80.5552096308605 169.588855386427 0.475002967897311 0.635109902728153 ICE1 other 9.56862926918437e-17 1 1.01515342021016e-17 10.3669637502521 0.475002967897311 0.551392504536311 31.7807032643197 30.9117141746698 1.02811196702776 0.30468596466314 2.3852220852813 54.106474029628 0.0440838573952387 0.964865491884159 HHIP other 1 1 1 1.02811196702776 0.0440838573952387 3.23029469946185e-07 37.2990904521575 8.57187320408145 4.35133483243753 1.83061463559625e-05 -24.5205388434076 15.003821278923 -1.63428625198658 0.10319771850282 ANAPC10 essential 0.00346481409464278 1 0.201733732842707 4.35133483243753 -1.63428625198658 5.91133372842853e-11 566.772113855284 85.5938429865066 6.62164583432283 1.5326199311098e-10 5.81086775408483 149.819612606293 0.0387857614433637 0.969085766428264 ABCE1 essential 7.45360069817554e-07 1 2.07516738672267e-06 6.62164583432283 0.0387857614433637 1.1342671110736e-08 301.970647975378 66.6272742530984 4.53223775639201 8.2986357788369e-06 -263.599977967047 116.621383843999 -2.26030569419117 0.0244847195073991 OTUD4 other 0.000131246047422326 1 0.0936998965788474 4.53223775639201 -2.26030569419117 7.49501015623793e-05 50.1480199706296 17.3270340656828 2.894206808882 0.0040664241488093 -60.6608203065581 29.989260520389 -2.02275145348503 0.04394331809528 LSM6 other 0.655138837756757 1 1 2.894206808882 -2.02275145348503 1.05885194804546e-05 106.202776774871 28.2779146798534 3.75567922802085 0.000205769441575495 -71.5515061913035 48.8668655034257 -1.4642131320309 0.144129809953801 TMEM184C other 0.100792116934448 1 1 3.75567922802085 -1.4642131320309 8.25183604614984e-05 17.4833295040536 7.97798343441818 2.19144720564698 0.0291490757474882 -37.3753161296401 13.7866970705597 -2.71096956278614 0.00707538803750583 PRMT9 other 0.716919515689498 1 1 2.19144720564698 -2.71096956278614 0.0794172884339313 344.689690009204 319.839059565387 1.07769729712683 0.282004066581832 -659.824075342359 478.364365966098 -1.37933366756905 0.168782936535653 ITGA2 other 1 1 1 1.07769729712683 -1.37933366756905 1.00113161810656e-08 116.988913382042 28.2737066283394 4.13772820521457 4.51644482560765e-05 -110.42016325688 42.2467231850152 -2.61369770084431 0.00939107394881706 MOCS2 other 0.000116201346913629 1 0.484072556408628 4.13772820521457 -2.61369770084431 0.727389533019361 -72.1715343846641 108.757111906588 -0.663602895658468 0.507423792817967 21.4177398124904 151.231081887778 0.141622605255073 0.887467506439357 EDIL3 other 1 1 1 -0.663602895658468 0.141622605255073 2.72042151745033e-08 42.3841130242936 12.7226297520722 3.33139561947798 0.000965233778372034 -58.6369833040579 17.7409191395538 -3.30518294135761 0.00105687324198041 TMEM161B other 0.000309284722318928 1 1 3.33139561947798 -3.30518294135761 0.000194504157862186 76.1421797133448 37.7100286583586 2.01914934626992 0.0443078070664466 -135.34096601244 54.4354671372162 -2.48626443622289 0.0134205730101853 ELOVL7 other 1 1 1 2.01914934626992 -2.48626443622289 4.36341416657458e-08 76.8282056983966 16.1962418992145 4.7435822567038 3.1720711284368e-06 -30.7793533128765 23.3797221858031 -1.31649782098637 0.188952089296 NDUFAF2 other 0.000490360484039651 1 0.036767476449711 4.7435822567038 -1.31649782098637 0.0887269102808531 10.5104556080079 5.2140104779653 2.0158102198731 0.0446553168734679 -0.472623746125011 7.66624047886377 -0.061650002687505 0.950880043304368 ZNF474 other 1 1 1 2.0158102198731 -0.061650002687505 1.47197523983936e-10 86.5911838940272 12.4968275125707 6.92905329828101 2.37264092774388e-11 -11.0827387607141 82.0675171153995 -0.135044158154925 0.892662666928865 LMBRD2 other 1.83128439588415e-06 1 3.25929684244177e-07 6.92905329828101 -0.135044158154925 2.03840293824283e-14 409.502176246707 49.0731426219765 8.34473103549148 2.27179261819275e-15 114.516219381282 329.292553662745 0.347764375803551 0.728249411194201 NIPBL other 2.77406255865467e-10 1 3.28319469181217e-11 8.34473103549148 0.347764375803551 0.840644213738521 -0.478399456964638 4.58731814082114 -0.104287394568846 0.917006817841625 3.21231470648599 6.60718389401118 0.486185152103555 0.627169711726501 RNF180 other 1 1 1 -0.104287394568846 0.486185152103555 0.0482029269802161 -51.478942197251 27.81311737728 -1.85088717308988 0.0651129469919108 -87.3314328679031 38.8565277971377 -2.24753568625183 0.0252909674384802 ADGRV1 other 1 1 1 -1.85088717308988 -2.24753568625183 7.96233177292329e-11 178.415466869973 39.1273560105911 4.55986514452137 7.29802981295355e-06 -181.261900001687 55.4035295203915 -3.27166701419217 0.00118583300647593 SLC25A46 other 9.99352260819603e-07 1 0.0827085718702026 4.55986514452137 -3.27166701419217 0.0110753010181308 99.5658446286331 50.6299844742737 1.96653911042033 0.0501003091727569 -98.9744519086357 71.7111270641346 -1.38018262940029 0.168493847737215 STARD4 other 1 1 1 1.96653911042033 -1.38018262940029 1.92755034501297e-08 49.3818552693858 17.1974239673738 2.87146815494408 0.00435817757081551 -97.9068978179134 25.414794373833 -3.85235844830277 0.000141336204423854 PGGT1B other 0.000220993647055737 1 1 2.87146815494408 -3.85235844830277 0.252516411081747 -34.1085175423331 40.0595866464227 -0.851444570394214 0.395159151901402 53.6272757788995 55.1038057953055 0.973204572804084 0.331186709381092 F2RL2 other 1 1 1 -0.851444570394214 0.973204572804084 0.00347859730134831 20.1561745278477 7.98234723135763 2.52509367779276 0.0120495351483687 -12.9137672934109 11.7965175418345 -1.09471013353002 0.274466931408229 CCDC112 other 1 1 1 2.52509367779276 -1.09471013353002 0.28048725755415 47.8928259276692 36.4975646424734 1.31221977128673 0.190392377849174 -167.297758811897 215.210258783799 -0.777368884538005 0.437519077743527 ANKRD33B other 1 1 1 1.31221977128673 -0.777368884538005 2.29595366204344e-17 186.825235435095 20.3919000402087 9.16173750688819 6.45959636820236e-18 -88.1067493643273 120.242162120581 -0.732744220583562 0.464254203171847 CMBL other 3.25152957618592e-13 1 9.48204150888424e-14 9.16173750688819 -0.732744220583562 0.111381910214221 1.72753699645736 3.87787092231762 0.445485946041982 0.656269839181812 -9.99754816377141 5.74367773246759 -1.74061788098899 0.0827117981722985 C5orf63 other 1 1 1 0.445485946041982 -1.74061788098899 3.47609418379035e-05 169.37833897825 59.6671269238208 2.8387212140196 0.00481898787817124 -203.897061796434 88.3754913811949 -2.30716750322726 0.0216835149091371 PRRC1 other 0.315316503411623 1 1 2.8387212140196 -2.30716750322726 0.0687214546109525 182.518338016266 91.3242619326509 1.99857446590554 0.046500095679431 236.33013899595 125.620726902478 1.88129892911238 0.0608389431247182 F2RL1 other 1 1 1 1.99857446590554 1.88129892911238 7.73328480621667e-11 115.973972449463 29.1999139546099 3.97172308897005 8.81862936225402e-05 -152.815454907128 40.1658260230236 -3.80461377339862 0.000170127909352069 AGGF1 other 9.7114590596469e-07 1 0.919783042483094 3.97172308897005 -3.80461377339862 2.50715321869796e-06 118.316467538604 34.1195458760717 3.46770346734246 0.000596726348964702 -101.38533518164 46.9330062332774 -2.16021395854573 0.0314982158619365 WDR41 other 0.0251542682431966 1 1 3.46770346734246 -2.16021395854573 2.76803971296563e-08 155.373756279259 43.6868495321215 3.55653378403992 0.000434081154116922 -199.576633223499 65.2771234868453 -3.05737481314901 0.00242605795407845 NDUFS4 other 0.000314476991790025 1 1 3.55653378403992 -3.05737481314901 0.479764828833389 27.9614983689703 114.106402928238 0.245047584109328 0.806576655891422 198.532686780923 165.419752723498 1.20017521192148 0.230959050045782 SCGB3A2 other 1 1 1 0.245047584109328 1.20017521192148 0.804133515585861 -8.34907207385465 16.6318690880741 -0.501992411655124 0.616022449073905 -16.5520557487511 28.1341537678118 -0.588326056840149 0.556733705870744 ESM1 other 1 1 1 -0.501992411655124 -0.588326056840149 5.06249419352158e-06 40.3509018158765 43.9229689515993 0.918674278606735 0.358957894297738 -277.584470291163 63.6641326312194 -4.36013904248248 1.75446393578555e-05 GRPEL2 other 0.0495884884901293 0.256678073805426 1 0.918674278606735 -4.36013904248248 9.32275252887599e-06 14.282922165985 9.08229627258525 1.57261134599823 0.116800105165369 -46.491984395066 12.905596265521 -3.60246697932705 0.000365484539106335 ARSK other 0.0892187417013433 1 1 1.57261134599823 -3.60246697932705 0.76707588385614 52.5554401433152 84.075809458522 0.625095856724912 0.532355031741779 -10.4866316652816 119.468515450631 -0.0877773664946489 0.930108702987912 RHOBTB3 other 1 1 1 0.625095856724912 -0.0877773664946489 0.134073754447145 97.5405823695389 53.7741986883829 1.81389188028219 0.0706427368046177 -10.0753751954919 90.9634128688906 -0.110762941689687 0.911874647265983 GPX8 other 1 1 1 1.81389188028219 -0.110762941689687 3.99668845333538e-08 22.2842435686194 4.68852476754668 4.75293288901189 3.0342954963848e-06 -12.7682024279016 6.77032964636742 -1.885905575477 0.0602131903181147 TIGD6 other 0.000450186987383698 1 0.0352069306445528 4.75293288901189 -1.885905575477 0.800803047105609 81.51627321217 151.957086936912 0.536442721134902 0.592025335049418 -30.8616801659417 209.4885078532 -0.14731920372247 0.88297284993838 SERINC5 other 1 1 1 0.536442721134902 -0.14731920372247 0.129142204154075 -20.5521918064475 15.1711980334024 -1.35468482852823 0.176479655354994 -54.8695724470497 28.3195834388163 -1.93751340183354 0.0535678209413781 ENPP6 other 1 1 1 -1.35468482852823 -1.93751340183354 2.93550000476353e-05 3.69271468744641 1.15058013997942 3.2094371866287 0.00146522157208509 -4.33666933820321 2.57342837492245 -1.68517195988946 0.0929333383788807 CAGE1 other 0.26851018543572 1 1 3.2094371866287 -1.68517195988946 3.15929066952873e-06 64.5033464584831 46.9850853240715 1.37284727724942 0.170764137082156 -343.757773972507 87.6974562603273 -3.91981465177362 0.000108485733635701 CASP3 other 0.0314507386151585 1 1 1.37284727724942 -3.91981465177362 1.32288094065871e-06 15.9155110169415 11.8235384365791 1.34608696899931 0.179230261498426 -90.6514657954696 22.0685827796713 -4.10771578313466 5.08387885539767e-05 PRIMPOL other 0.013578049974921 0.733349524891114 1 1.34608696899931 -4.10771578313466 3.36981349241992e-10 331.234507024834 144.510173139849 2.29211895486613 0.0225476594246188 -1026.1193508906 205.700591265294 -4.98841225773244 1.00061682749537e-06 ERAP1 other 4.14857739051816e-06 0.0149942431600181 1 2.29211895486613 -4.98841225773244 9.12455683816445e-06 397.686325047089 194.864126140999 2.04083908579116 0.0420871031349724 -908.320314589056 277.37608427614 -3.2746886486608 0.00117363352694265 ERAP2 other 0.0874315036232917 1 1 2.04083908579116 -3.2746886486608 0.315282245643995 562.563497239249 914.264532444609 0.615318080572411 0.538783392387621 1920.80556714925 1261.90458979166 1.52214801553767 0.128962629176415 CMYA5 other 1 1 1 0.615318080572411 1.52214801553767 0.0935952196974423 37.1534399350049 17.1911568947421 2.16119486096763 0.031431134984982 -14.8783282248237 118.386134419402 -0.125676273642949 0.900068102451063 EGFLAM other 1 1 1 2.16119486096763 -0.125676273642949 2.23683635765848e-10 212.158955565734 42.2587815878162 5.02047024533482 8.58847473892232e-07 -169.76666079378 78.9913404959723 -2.14918065357349 0.0323720893894001 CFAP97 other 2.77188761441039e-06 1 0.0102711336132011 5.02047024533482 -2.14918065357349 1.9811807418899e-14 186.223383837451 22.3139926407221 8.345587759028 2.25834637167061e-15 187.452889992065 153.977417779946 1.21740507598302 0.22436134585761 RICTOR essential 2.69698134393472e-10 1 3.26398801097553e-11 8.345587759028 1.21740507598302 4.74767691570277e-12 108.902221642537 29.8473130059363 3.64864407127295 0.00030785972203756 -187.882833044526 41.1964589443606 -4.5606549169257 7.28007627274211e-06 PAPD4 other 6.16011079812435e-08 0.107519446472128 1 3.64864407127295 -4.5606549169257 0.390541398310462 -19.9523060538226 18.7098550241041 -1.06640623500919 0.287043949684179 -31.6071852370481 26.8996751286598 -1.17500248928184 0.240867286155661 EBF1 other 1 1 1 -1.06640623500919 -1.17500248928184 0.00368162079082009 7.57972996494041 14.9733851643825 0.506213516965454 0.61305533253916 -59.0007583857572 20.5965806756551 -2.86458996834826 0.00445149779854356 ANKRA2 other 1 1 1 0.506213516965454 -2.86458996834826 1.32305076710581e-08 111.658694945719 33.7486735000949 3.30853581387147 0.00104471640613571 -185.664308455849 48.3912894951839 -3.8367299237671 0.000150210576590284 UBLCP1 other 0.000152640367000997 1 1 3.30853581387147 -3.8367299237671 4.32386870654602e-13 87.0872112539482 17.2707103890166 5.04247997287544 7.70999308813624e-07 -84.9404287987666 23.7566572921272 -3.5754368871969 0.000403590820990807 UTP15 essential 5.73993570793985e-09 1 0.00923425872166078 5.04247997287544 -3.5754368871969 5.02923208809238e-06 -13.0374022586233 18.613405064841 -0.700430803133906 0.484172058444613 -165.065841204859 34.3843820924564 -4.80060513406966 2.44174907440257e-06 TLR3 other 0.0492965329274815 0.0363942699539703 1 -0.700430803133906 -4.80060513406966 0.0123596535120617 -2.08750416281821 1.37337095854813 -1.51998565997422 0.129511336765673 -7.5553219780171 2.54042932474188 -2.97403352434721 0.00316467079913404 KLKB1 other 1 1 1 -1.51998565997422 -2.97403352434721 4.53715466218918e-12 286.762898774152 50.4300068152812 5.68635455126009 2.92655940031601e-08 -158.132190367257 69.368796196836 -2.27958677441299 0.0232901051507654 NSA2 essential 5.88877303605533e-08 1 0.000372112027750181 5.68635455126009 -2.27958677441299 2.68920098789853e-07 121.911915359177 34.5833060745879 3.5251665961676 0.000484964954376196 -125.361379516125 47.5709297380849 -2.63525182724696 0.0088168090097582 GFM2 other 0.00289842082475703 1 1 3.5251665961676 -2.63525182724696 0.626992240940258 -1.01224647853237 1.59731581042327 -0.633717184746413 0.526722381612985 -7.69568952998697 9.72479404709396 -0.791347301826577 0.429333050096855 TERT other 1 1 1 -0.633717184746413 -0.791347301826577 3.99369593517879e-21 114.790022185859 11.3351843552729 10.1268773923788 4.64431999211268e-21 -72.766692327826 66.6028906104043 -1.09254555862263 0.275425601327064 CCDC127 other 5.83958219641843e-17 1 6.92653883623685e-17 10.1268773923788 -1.09254555862263 0.584850779417292 -81.0694441465494 85.7380282574808 -0.945548268302706 0.345103764657312 -148.698932375459 191.722835450121 -0.775593225639235 0.438571084211491 FOXQ1 other 1 1 1 -0.945548268302706 -0.775593225639235 4.61319084470616e-06 9.70604165077425 2.3454246948587 4.13828748032305 4.49210814147166e-05 -8.29582093726956 5.67181531729907 -1.46263946782034 0.144559905116884 ADGRF2 other 0.0453430528126168 1 0.481509071684347 4.13828748032305 -1.46263946782034 0.430751703608227 -14.6306929356993 16.5169532452413 -0.885798531876003 0.37639125609254 -30.3113751180758 24.8898666424955 -1.21781990853755 0.224189622094386 ACSL6 other 1 1 1 -0.885798531876003 -1.21781990853755 0.679822569714723 18.1965123635194 27.1622477139848 0.669919240672809 0.503392393543546 31.8853214960311 40.8426686556225 0.780686535566075 0.435563999619413 CSF2 other 1 1 1 0.669919240672809 0.780686535566075 2.1871543795412e-12 285.3483528418 68.5105070143866 4.16503052271791 4.01161237856968e-05 -450.538160170549 102.53218605969 -4.3941144482013 1.51605215007799e-05 SEPT8 other 2.8588294894983e-08 0.222162282072428 0.431448911315169 4.16503052271791 -4.3941144482013 9.30463368071677e-05 23.0201761795583 11.3291749161623 2.03193757267509 0.0429883135878842 -48.0236595470819 16.9551375552191 -2.83239574970592 0.00491387786533251 SHROOM1 other 0.804571674371579 1 1 2.03193757267509 -2.83239574970592 0.00103221059937251 9.67944974055753 14.9653634912721 0.646790152888879 0.518232867179305 -71.30783958811 22.3970234757683 -3.18380876214462 0.00159688924103866 GDF9 other 1 1 1 0.646790152888879 -3.18380876214462 0.00194073227590124 93.6995937412015 140.360010706004 0.667566162683355 0.504893204847245 -630.808760709546 210.061483416347 -3.00297203680728 0.00288495548917863 UQCRQ essential 1 1 1 0.667566162683355 -3.00297203680728 0.365756508157477 5.22025936057547 4.92071581189627 1.0608739785287 0.289549708858306 -6.69771429394602 10.9846743073598 -0.609732624430976 0.542472996246318 GJB7 other 1 1 1 1.0608739785287 -0.609732624430976 1.02934820843501e-07 58.4154219219878 12.1039011309845 4.82616482816863 2.16159439943278e-06 -52.6922797787585 29.1599070328004 -1.80701124045039 0.0717026024892245 SLC35A1 other 0.00113516520426213 1 0.0252863312845646 4.82616482816863 -1.80701124045039 0.0441500635562052 4.96571250022732 4.71840377305213 1.05241364221257 0.293408842186064 -19.3331839065915 10.3982650688879 -1.85927015502204 0.063912328704544 GRIK2 other 1 1 1 1.05241364221257 -1.85927015502204 0.479808847911046 4.75117474092462 6.57172927208678 0.72297176956225 0.470230300832272 -11.8639212633754 15.3895057233645 -0.770909831455045 0.441334579964859 FABP7 other 1 1 1 0.72297176956225 -0.770909831455045 0.00157189777705348 8.50495825713852 8.06239367290293 1.05489245529191 0.292272806700538 -35.0885345063226 12.1998715712921 -2.87613966272322 0.0042966767970929 TLX3 other 1 1 1 1.05489245529191 -2.87613966272322 0.502162962435723 -30.1618648654012 54.5720377882678 -0.552698159860279 0.580857184920304 -142.463598056702 125.992808792784 -1.13072801076296 0.259018983003591 TXLNB other 1 1 1 -0.552698159860279 -1.13072801076296 0.122992442208579 -12.7828335177155 57.4555668993045 -0.222482071060554 0.824081006020523 -270.940276634655 132.650136366749 -2.04251788995953 0.0419220010702957 CITED2 other 1 1 1 -0.222482071060554 -2.04251788995953 0.0152813976014856 16.2641496307936 21.0842033682844 0.77139028431393 0.441044861070314 -75.5198283658475 31.9374103759177 -2.36461965691473 0.0186451363680045 CREBRF other 1 1 1 0.77139028431393 -2.36461965691473 0.00123421000189552 249.686926538484 86.1149330145531 2.89946142669922 0.0039973012873319 -299.854085091462 200.871227709926 -1.49276772243596 0.136486335861958 DCBLD1 other 1 1 1 2.89946142669922 -1.49276772243596 1.02522313506069e-09 199.960887950302 71.7014217682612 2.78879948289694 0.00560711868566556 -514.17859425927 109.17859208911 -4.70951845431021 3.70562830563874e-06 SFXN1 other 1.23795693558578e-05 0.0550878703916256 1 2.78879948289694 -4.70951845431021 0.00657604133716495 -7.16061713141579 2.29465815052704 -3.12055943050651 0.00196952384472706 -0.423615553988254 5.41468891808256 -0.0782345136344904 0.937690404804183 SAMD3 other 1 1 1 -3.12055943050651 -0.0782345136344904 0.194274750417752 15.1808892760518 21.8114172207198 0.696006551175901 0.486929915612872 -75.2356160821864 51.4682498940334 -1.46178695092774 0.144780904243131 TMEM200A other 1 1 1 0.696006551175901 -1.46178695092774 0.694612185948997 -5.97514466987382 7.14693666254452 -0.836042762375131 0.403760579549499 -5.89198812760831 16.55374096934 -0.355930912445782 0.722129054952168 IL22RA2 other 1 1 1 -0.836042762375131 -0.355930912445782 0.30140555558669 -17.9252250847722 31.4817939281169 -0.569383851685877 0.569496376676519 -111.820497330163 72.7440772864307 -1.53717665411946 0.125241312723201 DACT2 other 1 1 1 -0.569383851685877 -1.53717665411946 1.31821185262112e-09 36.674166677254 11.0222006990121 3.32729984498839 0.000979378426877005 -115.143834195136 25.0054194408078 -4.6047551598845 5.97298353420755e-06 PDSS2 other 1.58567703751795e-05 0.0884539131580796 1 3.32729984498839 -4.6047551598845 0.00099896017198846 56.0024778074931 33.1087553683578 1.6914703432499 0.0917205671674895 -206.566708324917 72.5060153656175 -2.84895959712154 0.00467036437074626 STXBP5 other 1 1 1 1.6914703432499 -2.84895959712154 5.84321077026796e-06 43.6397737619791 8.73018199535442 4.99872440061399 9.56549987576886e-07 24.8040645312513 14.6051776120094 1.69830625756004 0.0904312282242129 IL31RA other 0.0569537753778018 1 0.0114164241017301 4.99872440061399 1.69830625756004 0.354645152808953 7.19671334835639 31.3494896257257 0.22956397167151 0.818577267670827 -91.4282864409607 68.7134268402329 -1.33057381424947 0.184276658885407 RAET1E other 1 1 1 0.22956397167151 -1.33057381424947 0.309281148306025 -30.6458830327293 20.3362626975614 -1.50695747239753 0.132808090401398 -38.2549407734534 47.2029866070996 -0.810434752611598 0.418292643083788 PI16 other 1 1 1 -1.50695747239753 -0.810434752611598 1.07689866256032e-26 203.96327093925 18.0998721835214 11.2687685786501 5.22783374941816e-25 -216.398336635133 86.5861748373966 -2.49922504420037 0.0129504053006194 DAGLB other 1.61437878504418e-22 1 7.87625432687341e-21 11.2687685786501 -2.49922504420037 0.00844600095691276 30.4868972959548 10.4968766958724 2.90437795729685 0.00393667001303495 -24.1450386582762 42.2758994392723 -0.571130099619988 0.568313592446213 KIAA0895 other 1 1 1 2.90437795729685 -0.571130099619988 3.74267685751884e-06 376.717068450815 79.5833110367565 4.73361894024268 3.32111901851738e-06 -307.79333493347 318.65270024831 -0.965921000178634 0.334815411267597 STK17A other 0.0370599862431516 1 0.0384552371154128 4.73361894024268 -0.965921000178634 0.0964091222063581 35.6667420310435 28.9821461119249 1.23064530464044 0.219365050410457 -189.689893031237 122.448510648402 -1.54914005917076 0.122342660738593 TRA2A other 1 1 1 1.23064530464044 -1.54914005917076 0.0138023724214481 216.179547070174 73.3818367372549 2.94595443071572 0.00345577713992423 100.254665861363 107.135958066654 0.935770470256028 0.350097017597055 GALNT10 other 1 1 1 2.94595443071572 0.935770470256028 1.04646986967621e-05 64.9782674926375 42.5088932702805 1.52858055088595 0.127356310569168 -239.03543318029 62.0621015956737 -3.85155234892905 0.000141781529237975 SAP30L other 0.0997076491827497 1 1 1.52858055088595 -3.85155234892905 4.50460240434956e-08 2266.32016740374 715.651046799856 3.16679501488601 0.00168977549055894 -3851.11814463112 1036.10907441973 -3.71690417515927 0.000238001818866279 RPS14 essential 0.000505911896032499 1 1 3.16679501488601 -3.71690417515927 0.279281386190023 6.06468059633697 57.1694162722088 0.10608260485747 0.915583281550687 127.516984679281 82.7690412021161 1.5406362430597 0.124393594064256 MYOZ3 other 1 1 1 0.10608260485747 1.5406362430597 2.45547954393142e-21 253.414880610163 26.2667856359703 9.64773094516488 1.79383913828141e-19 -237.98032232912 117.225769998529 -2.030102445325 0.0431834752086333 COG5 other 3.5948220523156e-17 1 2.65506130857032e-15 9.64773094516488 -2.030102445325 3.9649927106798e-09 65.1216928516249 12.0023679217516 5.42573709422842 1.15757054258327e-07 -47.7704170484819 33.7824832075049 -1.4140587817378 0.15833852279715 BMT2 other 4.68781088183673e-05 1 0.0014374710997799 5.42573709422842 -1.4140587817378 0.0444762449940514 7.56586479827147 3.25508929770968 2.3243186611178 0.020748130321433 -0.998317091189351 9.16194206474203 -0.108963480028015 0.9133012779938 GPR85 other 1 1 1 2.3243186611178 -0.108963480028015 1.58665144538628e-16 190.493175227458 33.5707098771234 5.67438627079105 3.11860281266537e-08 -228.086836034843 48.1361123784061 -4.73837260146423 3.24519429430927e-06 SLU7 other 2.2254373172988e-12 0.0482657747392618 0.000395906627067869 5.67438627079105 -4.73837260146423 1.68052085340238e-05 33.4728998565492 7.1701967148044 4.66833773018212 4.47314764451536e-06 -3.26832989201276 29.486417573778 -0.110841877750495 0.911811222331205 RP9 other 0.157246336252861 1 0.0513517349590363 4.66833773018212 -0.110841877750495 1.64471796277274e-07 270.17467206059 121.85333119492 2.21721203196662 0.0273109917982517 -740.710935374623 174.722121323948 -4.23936551228845 2.9364979746443e-05 PTTG1 other 0.00179307152301484 0.426937440533535 1 2.21721203196662 -4.23936551228845 1.20436271560573e-09 114.704398690459 23.5751723003032 4.86547445886466 1.79757477172229e-06 -83.6849753935073 35.203873307661 -2.37715249859441 0.0180362262674233 CAMLG essential 1.45053445467554e-05 1 0.0211179084181934 4.86547445886466 -2.37715249859441 0.80705819488659 -8.75956047270885 13.5837489779729 -0.644855885287128 0.519482606799683 -12.8677565414031 55.7781317132384 -0.230695366556156 0.817698892744489 BMPER other 1 1 1 -0.644855885287128 -0.230695366556156 0.000316345037368453 26.0368218884887 13.244865067015 1.96580499361453 0.0501882012273063 -50.8442401199874 18.885227868233 -2.69227570219117 0.0074712706226695 RELL2 other 1 1 1 1.96580499361453 -2.69227570219117 0.537007951145737 -2.70566314682913 2.63449483707041 -1.02701402513958 0.305191972030882 -3.03980524542039 3.90117758696736 -0.779201965984693 0.43643841490196 SMAD5-AS1 other 1 1 1 -1.02701402513958 -0.779201965984693 0.377379537878398 21.6299246397135 31.390449677084 0.689060681265234 0.491285949817862 100.745971239004 72.9842018678239 1.38038052976803 0.168436012850567 KCNK5 other 1 1 1 0.689060681265234 1.38038052976803 1.12374014685003e-13 127.279906833603 16.2332994408491 7.84066771498828 6.83060115664124e-14 -62.9792543173179 77.6568635027624 -0.810994050964698 0.417975639602402 ZNF12 other 1.50850877313148e-09 1 9.74043724937041e-10 7.84066771498828 -0.810994050964698 1.0230436945496e-05 90.4094765519226 18.5305646040538 4.87893804013637 1.68941432636783e-06 77.866352414654 83.4633411859968 0.93294075348757 0.351558359926461 SLC29A4 other 0.0975574467122501 1 0.0198945431073076 4.87893804013637 0.93294075348757 1.06821689856506e-06 96.5462156457632 19.0831784958386 5.05923138888088 7.15352589373826e-07 -50.0734389167174 82.4439225676767 -0.60736361586402 0.544045813273442 STEAP1 other 0.0110368169959742 1 0.00857707754659218 5.05923138888088 -0.60736361586402 0.00031368808856994 111.669471200494 31.8894688913904 3.50176641639344 0.000527874533722541 -187.710620841746 134.88588108946 -1.3916254193962 0.16500243714301 CDCA7L other 1 1 1 3.50176641639344 -1.3916254193962 0.959569551855427 -0.824433732028799 2.89010286112659 -0.285261034518138 0.775628705896967 -1.0529994692342 12.2245394612852 -0.0861381708954375 0.931410451237763 SP8 other 1 1 1 -0.285261034518138 -0.0861381708954375 2.98331674845911e-20 165.333999109398 16.8709084173681 9.79994645333922 5.76922500425644e-20 -102.176906323429 78.4857918797094 -1.30185227002652 0.19391809463322 MIOS essential 4.33654922556016e-16 1 8.56614528631996e-16 9.79994645333922 -1.30185227002652 0.000246972093181933 49.5617479699245 13.0003577585322 3.81233723644234 0.000165775535252056 -25.6308646535217 49.159775891526 -0.521378793712928 0.602471620470889 KIAA1324L other 1 1 1 3.81233723644234 -0.521378793712928 0.0388463775642576 18.2636800059229 7.14494691406886 2.5561673481381 0.01104771818005 11.6785426687304 19.628515064107 0.594978409247366 0.552281029872547 USP49 other 1 1 1 2.5561673481381 0.594978409247366 0.425897658584749 2.22855953208397 2.11569104637829 1.05334828348349 0.293031869024782 -4.08051945497229 7.90118074825569 -0.516444261305265 0.605925897600257 INTS4P1 other 1 1 1 1.05334828348349 -0.516444261305265 0.350415093795769 -16.8650861113164 19.8926990537156 -0.84780280774249 0.397183455602638 41.7591749100813 43.4789153453756 0.960446565383854 0.337557921389875 SYTL3 other 1 1 1 -0.84780280774249 0.960446565383854 0.441243600910089 11.8993746179978 41.3517331241975 0.287759997440948 0.773718494675689 252.110238905888 198.59999784632 1.26943726908283 0.205216314138678 HEY1 other 1 1 1 0.287759997440948 1.26943726908283 0.00159651165781803 71.3929272463847 19.9246693185324 3.58314239022177 0.000392837565894538 84.8520256244207 95.7342758322918 0.886328589073628 0.37611237250433 ZNF704 other 1 1 1 3.58314239022177 0.886328589073628 1.55807146456302e-05 2227.44343850469 500.049103694687 4.45444941716102 1.16749101754741e-05 -3201.88480617751 2402.64157248877 -1.33265187901533 0.183603161647087 FABP5 other 0.146209426234593 1 0.130315347378642 4.45444941716102 -1.33265187901533 0.310178592521158 -40.4534495942902 34.1198124853231 -1.18562930589644 0.236656693079045 -110.324599600663 77.7501595943388 -1.41896299861352 0.156892272044296 SHH og 1 1 1 -1.18562930589644 -1.41896299861352 0.00166443920669629 -62.0837275482298 17.2431280640628 -3.60049100821917 0.00036816333711747 -41.2198136218912 37.6878222187163 -1.09371704691976 0.274904289455997 TAGAP other 1 1 1 -3.60049100821917 -1.09371704691976 0.0368621644766877 10916.4909192106 5724.18225327384 1.90708304456363 0.0574339867217071 -31650.0111921788 24891.9670432657 -1.27149498218307 0.204505741380334 COL1A2 other 1 1 1 1.90708304456363 -1.27149498218307 0.45772963084938 131.290738313674 123.180028043769 1.0658443612874 0.287297516421217 -109.066945825125 270.760413923576 -0.402817177905148 0.68735169880532 FNDC1 other 1 1 1 1.0658443612874 -0.402817177905148 0.00453216772889657 45.8553436174573 15.6553451462688 2.92905350786126 0.00364563570746159 -95.7062829812977 75.7194851712866 -1.26395844827522 0.20717066127877 CHMP4C other 1 1 1 2.92905350786126 -1.26395844827522 0.0825334756842117 24.7382410569332 12.2089625505828 2.02623613222176 0.0435750300884388 2.44843008826436 26.8443730683382 0.0912083169918458 0.927384492225445 SLC13A4 other 1 1 1 2.02623613222176 0.0912083169918458 0.508486992025337 67.6989279052998 64.6271488165239 1.04753078458554 0.295645396573376 -77.8132947996762 259.172887455133 -0.300237017705592 0.764191319659585 PGAM2 other 1 1 1 1.04753078458554 -0.300237017705592 4.4437517345393e-12 343.237487279242 48.8177628955414 7.0309958285817 1.27840787242242e-11 -237.091947230054 211.624196467588 -1.12034422900392 0.263420549443803 BRI3 other 5.76843412660546e-08 1 1.76535343102812e-07 7.0309958285817 -1.12034422900392 1.86221195201592e-17 388.192184154176 42.8315747017103 9.06322466212466 1.37868276295585e-17 -42.2751605995717 185.674169442917 -0.227684662473035 0.820039109088301 LMTK2 other 2.64061654795857e-13 1 2.02032172083551e-13 9.06322466212466 -0.227684662473035 0.00954483991868786 6673.83685590579 2439.94518550466 2.73524048636585 0.00658214236594923 3212.42070509749 4704.42941638025 0.682850229171731 0.495197081344115 CTSB other 1 1 1 2.73524048636585 0.682850229171731 0.37358937195261 0.489042582532886 1.72628226195201 0.283292363775954 0.777143666066605 -10.6161126500462 8.04835535557582 -1.31904124271693 0.188138325984922 SOX17 other 1 1 1 0.283292363775954 -1.31904124271693 0.307017435720918 15.6577145939555 30.4784046930593 0.513731435475069 0.607796537598292 82.475369329552 56.9533785258977 1.44812075181895 0.148568498551929 DLC1 other 1 1 1 0.513731435475069 1.44812075181895 0.00395583272458457 32.5790635932809 10.0524781222187 3.24089873135583 0.00131734036364444 -11.4495219545277 40.9709640924392 -0.279454540749766 0.780077119929385 ADCY1 other 1 1 1 3.24089873135583 -0.279454540749766 0.0248431924694044 6.22802013024113 2.64013854514147 2.35897473702745 0.0189280110929499 25.2978834524748 14.9728241082385 1.68958663172668 0.0920840799226329 SUN3 other 1 1 1 2.35897473702745 1.68958663172668 0.609098905072776 1.97535653759302 2.23132372322334 0.885284603499594 0.376669966836818 -4.21878137170932 12.6543425904086 -0.333386056333497 0.739061908568123 C7orf57 other 1 1 1 0.885284603499594 -0.333386056333497 0.421496181237017 -3.06567967679841 2.76966113559607 -1.10687897425352 0.269188137625548 7.73829795161642 13.1179413211046 0.589901857478718 0.555678010484127 HNF4G other 1 1 1 -1.10687897425352 0.589901857478718 0.000238772582932524 78.0202266584527 20.9576542512982 3.7227556921653 0.00023325403963086 -138.731949369993 99.3077140546539 -1.39699066372268 0.163396608651379 PEX2 other 1 1 1 3.7227556921653 -1.39699066372268 3.94632078368725e-07 39.6843335123574 7.27028354332141 5.45842996024715 9.68596026664147e-08 -29.4392663574052 40.0023194194965 -0.735938985154371 0.462310319080947 MED30 essential 0.00420322626670529 1 0.00120696750882619 5.45842996024715 -0.735938985154371 0.168322086821303 -6.46326937985655 4.45827290634185 -1.44972493062563 0.148114581947734 27.8562920525854 24.641970115068 1.13044094780197 0.259137029652121 TNFRSF11B other 1 1 1 -1.44972493062563 1.13044094780197 0.421220811679096 -11.5470874738494 15.2511306636151 -0.757129928825378 0.449534408847928 -82.209548247908 70.602240188951 -1.16440424592609 0.24513578731296 SBSPON other 1 1 1 -0.757129928825378 -1.16440424592609 0.0132620505412555 76.1391187784897 25.9751053647551 2.93123426100903 0.00364776520544326 73.590942342311 165.139356328283 0.445629339840821 0.656200978813122 PHKG1 other 1 1 1 2.93123426100903 0.445629339840821 0.0485377527234231 -18.5705636627962 12.8357876326334 -1.44678022060624 0.148943466194727 -71.0943915889169 28.9362601956036 -2.45693089253181 0.0145467485974102 EN2 other 1 1 1 -1.44678022060624 -2.45693089253181 0.445650809673152 2.24174454828662 1.92612982582391 1.16385952713635 0.245353427498485 -4.9990926007234 10.742391977552 -0.465361216679658 0.64199132962553 CSMD3 other 1 1 1 1.16385952713635 -0.465361216679658 0.0516351469337359 112.236081702564 53.1431093207823 2.11195925750383 0.0355600120491837 -215.873341695101 267.816097446683 -0.806050658467522 0.420885687163109 SPIDR other 1 1 1 2.11195925750383 -0.806050658467522 8.72182114091683e-12 87.9928090449125 12.6519552455668 6.95487830434311 2.03465802520217e-11 -42.3623561746515 49.5234516085195 -0.855399912540909 0.392977893259079 ORC5 essential 1.12354499937291e-07 1 2.79867211366558e-07 6.95487830434311 -0.855399912540909 0.594230911894433 0.0431889808197742 0.211734244700047 0.203977305990148 0.838501299392143 0.366529275184938 0.407544107176854 0.899360998552932 0.369138783537363 DEFA5 other 1 1 1 0.203977305990148 0.899360998552932 1.45691815167766e-28 315.234529935754 26.2475632355456 12.0100493560808 1.34076447364743e-27 -186.395484759256 126.163751754436 -1.47740917789171 0.140568257815188 DNAAF5 other 2.19441012005689e-24 1 2.02978333665484e-23 12.0100493560808 -1.47740917789171 0.733705933056609 0.000614157044214455 0.0667909755372165 0.00919520997072788 0.992669135077023 0.0785291311938662 0.128558649222508 0.610842846193481 0.541738606696755 DEFA6 other 1 1 1 0.00919520997072788 0.610842846193481 4.03872171034818e-06 64.5278154762055 12.7394629821689 5.06519117536769 6.905771020717e-07 4.26265415229233 64.4598543885273 0.0661288206858098 0.94731656028676 OSGIN2 other 0.0398541058377159 1 0.00828899695616662 5.06519117536769 0.0661288206858098 0.183471463389674 110.875572397438 132.655383379219 0.835816606707021 0.403883679847126 -186.469608884249 255.333849553129 -0.73029725283427 0.465744484982454 DEFB1 other 1 1 1 0.835816606707021 -0.73029725283427 1.08821560101384e-25 1190.07168218013 101.816624734323 11.6883827693706 1.901718603136e-26 337.905679537617 489.400377939072 0.690448342031491 0.490422321593402 SUN1 other 1.62666468039548e-21 1 2.87330663747818e-22 11.6883827693706 0.690448342031491 0.0405727136278749 75.4732314309852 29.7223966368386 2.53927139029704 0.0115814262484485 48.5461758232948 163.170918654165 0.297517328600611 0.766264632195552 OXR1 other 1 1 1 2.53927139029704 0.297517328600611 0.00193066873296371 11.985989183958 3.35670737762689 3.57075783961597 0.000411494405282833 10.2398949005505 16.1952776346628 0.632276588987525 0.527664808019412 GPR146 other 1 1 1 3.57075783961597 0.632276588987525 0.282250537718941 8.98103962124611 5.64501650268037 1.59096782391721 0.112619856431579 10.5363602579647 27.2357996179563 0.386857019282012 0.699123275540404 GPER1 other 1 1 1 1.59096782391721 0.386857019282012 3.103955776059e-05 260.853713989858 59.1651673025852 4.40890689374353 1.42438934661042e-05 -140.556604625229 264.745138109594 -0.530912883344602 0.595850908909231 TMEM184A other 0.283173885449863 1 0.158064485793358 4.40890689374353 -0.530912883344602 0.000434113030767033 123.34941927648 31.0675845913619 3.97035755752882 8.86692691414687e-05 120.845990713754 69.0288774873612 1.75065849413356 0.0809630193271232 NOS3 other 1 1 0.924465800068953 3.97035755752882 1.75065849413356 0.491117262093636 22.3432711791247 41.6858550917878 0.535991672233356 0.592342572733132 -190.944429857481 201.12387548274 -0.949387184386609 0.343151533465844 MICALL2 other 1 1 1 0.535991672233356 -0.949387184386609 0.724746883090796 48.190834332705 64.5517465847084 0.746545785085246 0.455889347423093 -68.3402843926676 317.678480949189 -0.215124059358614 0.829808495871535 CA3 other 1 1 1 0.746545785085246 -0.215124059358614 1.40535058776364e-18 935.378931449475 100.251452804719 9.33032794319211 1.91738035563481e-18 -334.254405118486 446.600320201815 -0.748441928943176 0.454750323859858 INTS1 essential 2.0144295325004e-14 1 2.82487647795676e-14 9.33032794319211 -0.748441928943176 2.18751922033501e-08 28.6751631946361 15.6513020241253 1.83212637200633 0.0678618496955726 -141.778347988646 34.7755328955129 -4.07695687696966 5.76266757795158e-05 CDK5 other 0.000249924070923275 0.829363117818791 1 1.83212637200633 -4.07695687696966 3.73100357441377e-21 332.400049115446 67.5600533876293 4.92006788698469 1.38674678063884e-06 -814.987753025453 150.111272236816 -5.42922420735815 1.12083257204453e-07 SLC4A2 other 5.45659272758014e-17 0.00169391426613089 0.0164176951359833 4.92006788698469 -5.42922420735815 8.91278399869144e-07 134.583409639953 69.3776330047218 1.93986741563802 0.0532742261350103 -515.109687355437 154.149741347372 -3.34161888857569 0.000931541052570232 FASTK other 0.00926305640984002 1 1 1.93986741563802 -3.34161888857569 5.97449221376688e-14 106.272704947524 29.0792346646519 3.65459085058752 0.000300950184093138 -286.960112261157 64.6109748631891 -4.44135246169528 1.23280917916722e-05 TMUB1 other 8.06227484859424e-10 0.181025699868915 1 3.65459085058752 -4.44135246169528 0.00893596890309024 23.272958081654 14.5362013861792 1.60103437365566 0.110356012748589 -51.6795563321246 31.9874572569313 -1.61561939472154 0.107162080906065 FMC1 other 1 1 1 1.60103437365566 -1.61561939472154 7.54365555432474e-17 118.525444334564 24.5867121189601 4.82071143799512 2.21450026052068e-06 -192.136214761913 36.2389917979987 -5.30191943067587 2.1406399475559e-07 PHAX other 1.06109059027132e-12 0.00322894129689332 0.0258941515462684 4.82071143799512 -5.30191943067587 7.10559641598416e-06 319.48839150434 87.979290160568 3.63140451487222 0.000328141014675264 -222.338336504649 129.67495446713 -1.71458195160584 0.0873900959173041 ALDH7A1 other 0.0687324341318148 1 1 3.63140451487222 -1.71458195160584 0.000219551239906097 280.626931095665 71.4599188372756 3.92705359398311 0.000105485188892312 -237.479988303565 322.116273830542 -0.737249271759855 0.461514384521153 FOXK1 other 1 1 1 3.92705359398311 -0.737249271759855 0.000175126091586391 430.798666511691 104.641156926233 4.1169142158413 4.89510535423897e-05 -479.951253359257 606.628882280462 -0.79117771569828 0.429428139520392 COX6C other 1 1 0.522650398672095 4.1169142158413 -0.79117771569828 0.183900023573814 30.945668363604 16.7767400899463 1.84455789370836 0.0660317647819638 -1.12070357014096 92.9764313576486 -0.0120536307295985 0.990390385438317 OSR2 other 1 1 1 1.84455789370836 -0.0120536307295985 5.72651219780501e-25 8128.41963661998 709.401761412485 11.458132864564 1.05968729684422e-25 -4869.77675731341 4297.1916729106 -1.1332463450519 0.257959146748705 YWHAZ other 8.53651173326794e-21 1 1.59896216220824e-21 11.458132864564 -1.1332463450519 0.0147574548745511 51.2266109656015 18.2693908904322 2.8039583406379 0.00535822423068717 -77.0482677872382 104.391212521751 -0.738072352317821 0.461014797156981 BAALC other 1 1 1 2.8039583406379 -0.738072352317821 8.18047016821039e-05 403.205870900775 91.8114017370207 4.3916753613641 1.53361194648731e-05 -96.8028117696403 524.609912182049 -0.18452341353407 0.853720479844258 FZD6 other 0.710964662319165 1 0.169908867551329 4.3916753613641 -0.18452341353407 0.0394830229170259 162.672977917597 63.6875650640706 2.55423453155958 0.0111079698544942 1.394104899832 363.910443400608 0.00383090105028207 0.996945792744346 CTHRC1 other 1 1 1 2.55423453155958 0.00383090105028207 1.11812412785422e-17 148.53260914064 15.7909731881173 9.40617195477291 1.06191662073175e-18 20.1390009652466 90.2295455766572 0.22319741096487 0.823525171554542 SLC25A32 other 1.58918982291921e-13 1 1.56675178222762e-14 9.40617195477291 0.22319741096487 4.96888730198275e-23 297.191405664993 26.9981260831879 11.0078530913321 4.1978783892785e-24 77.656850824581 151.344105831115 0.513114471145897 0.60822640593183 DCAF13 other 7.34799054217208e-19 1 6.31151015828023e-20 11.0078530913321 0.513114471145897 0.0584748103327963 -55.7822393057527 24.023931113522 -2.32194469099003 0.0208632773664678 -94.7882078908016 121.763320235905 -0.778462739905239 0.436871495806699 TP53INP1 other 1 1 1 -2.32194469099003 -0.778462739905239 9.78986922338892e-08 167.629805313483 28.8013125419976 5.8202140985432 1.42765794206217e-08 29.9160198721564 145.977085336035 0.204936410418735 0.837752100477413 INTS8 essential 0.00108138895441554 1 0.000183596811349195 5.8202140985432 0.204936410418735 0.0223107013061499 3.9172060910086 1.56452365622262 2.50376916669083 0.0127933207249812 9.03849621697736 5.87078616968687 1.53957169546501 0.1246686927669 FREM1 other 1 1 1 2.50376916669083 1.53957169546501 0.0556340928353106 53.8429841918028 35.7474609078144 1.50620443590814 0.133001173376382 -314.712411278423 181.128149952799 -1.73751242620451 0.0832588631791912 GEM other 1 1 1 1.50620443590814 -1.73751242620451 0.000703031604566141 183.226324079791 47.7366240097324 3.83827570299976 0.000149309887597165 3.53218129406363 241.94915514915 0.0145988577306096 0.988361308114066 PDP1 other 1 1 1 3.83827570299976 0.0145988577306096 0.00749763891983435 19.1105752889337 6.07173097584279 3.14746739685399 0.00180192329422253 3.76411318204083 30.7740693937339 0.122314443822216 0.902726771289822 TMEM67 other 1 1 1 3.14746739685399 0.122314443822216 1.70362662760925e-16 247.244036855249 27.5264752429865 8.98204491031756 2.45408013760073e-17 255.614654249375 161.720518177617 1.58059507309169 0.114971042657303 WASHC5 other 2.38882525723369e-12 1 3.59056464932363e-13 8.98204491031756 1.58059507309169 1.83591478625308e-20 139.09326829886 14.7098719308135 9.45577697433889 8.01644975489025e-19 -99.080051576266 46.8853497219981 -2.11324117584173 0.0353738497479759 RPP25L other 2.6725411543486e-16 1 1.18346847731445e-14 9.45577697433889 -2.11324117584173 1.24005524196429e-23 149.200034970737 13.3751012626653 11.1550583461531 1.45208992176656e-24 59.5100599795275 45.0685178411024 1.32043525791865 0.187651381436298 FAM219A other 1.83800987963947e-19 1 2.18597616822738e-20 11.1550583461531 1.32043525791865 6.22544672886031e-39 165.678369980842 11.3143371116079 14.6432237564202 2.02551898721778e-37 -104.704701603635 42.2855964376045 -2.47613160093731 0.0138049263286919 SNAPC3 essential 9.50252188693237e-35 1 3.09317004538027e-33 14.6432237564202 -2.47613160093731 5.31090353464317e-24 108.390739104678 10.7178177031921 10.1131351648568 5.35762720912815e-21 -105.348760911003 36.0073251011381 -2.92575915081437 0.00368662882724534 NUDT2 other 7.88138084541047e-20 1 7.98661488064734e-17 10.1131351648568 -2.92575915081437 2.25601356772488e-12 139.84611770457 18.3069046043559 7.63898216147884 2.61291063216689e-13 85.2735346738472 107.730339149865 0.791546145187773 0.429217226833276 TMEM65 other 2.94770732758933e-08 1 3.6949169249472e-09 7.63898216147884 0.791546145187773 1.65581278279604e-27 198.562822839468 34.4711230658618 5.76026555502956 1.99208906067672e-08 -1279.11896173559 128.830525759975 -9.92869472658003 2.12814021494329e-20 PSIP1 og 2.48885219382072e-23 3.26924899819588e-16 0.000255067083329047 5.76026555502956 -9.92869472658003 2.31524948392092e-18 10.1102343870102 1.60392562291579 6.30343093380523 9.81570459089444e-10 -38.1324750278267 6.00912904862859 -6.34575738334816 7.69683323269156e-10 CCDC171 other 3.31219591169727e-14 1.17538340296433e-05 1.30676475218578e-05 6.30343093380523 -6.34575738334816 1.36454702899211e-50 694.493696069752 40.2461626859833 17.2561469148865 1.95772541789692e-47 -357.744098511369 135.681720555211 -2.6366418191594 0.0087880964443241 UBAP1 essential 2.0913047766333e-46 1 2.99903956767628e-43 17.2561469148865 -2.6366418191594 0.43622012485339 -1.05554445470338 6.93791463911231 -0.152141458869035 0.879171242763863 16.3635384714688 13.1687990671111 1.24259914575935 0.214925364926761 DIRAS2 other 1 1 1 -0.152141458869035 1.24259914575935 5.04499732749508e-06 91.5711297337269 83.9173511573336 1.09120615070468 0.276003110238337 -753.573255613933 160.33726947301 -4.69992571340866 3.8721868359089e-06 SYK other 0.0494335176941804 0.0575445685684422 1 1.09120615070468 -4.69992571340866 0.742034050085137 3.0936181333994 4.00822033830292 0.771818381299176 0.440791595727976 0.950453458846837 8.00606330176757 0.118716705454602 0.905574289330928 NIPSNAP3B other 1 1 1 0.771818381299176 0.118716705454602 0.00185763107746854 277.201677834893 77.5833470165323 3.57295332690176 0.000407289862742294 18.683886294668 154.965828959479 0.120567782072482 0.904109054763114 ABCA1 other 1 1 1 3.57295332690176 0.120567782072482 1.3037975203913e-07 287.085190970581 52.3713438833787 5.48172282173753 8.55379729254755e-08 256.190512908527 99.9875511537453 2.56222409642373 0.0108578940270217 NFIL3 other 0.00142883170259682 1 0.00106802712994749 5.48172282173753 2.56222409642373 9.81686386642967e-06 34.683946502455 9.63586109689512 3.59946518050482 0.000376147274846207 -19.9164155899581 22.8390970081091 -0.872031656194057 0.38392772607895 LETM2 other 0.0937608667882697 1 1 3.59946518050482 -0.872031656194057 5.17862879002573e-10 64.3868149486152 17.6265553895264 3.65283026239337 0.000303081713071763 -138.052940755554 40.550517796499 -3.40446801316734 0.000747593252695802 METTL2B other 6.33449873595948e-06 1 1 3.65283026239337 -3.40446801316734 9.61639426667683e-07 26.3684682925563 7.56654209085059 3.48487697232807 0.000561476362169285 -49.8587216021767 14.7094633182502 -3.38956769009489 0.000788203160616936 FXN essential 0.00997220085454387 1 1 3.48487697232807 -3.38956769009489 0.0025669952734523 -10.3691401693858 3.11151182798067 -3.3325086783023 0.000961837962666526 -23.9140032515602 17.6190871781366 -1.35727821820616 0.175652314747369 TMEM71 other 1 1 1 -3.3325086783023 -1.35727821820616 0.971366000575178 0.867642914196749 17.2741483425735 0.050227825823307 0.959972272413698 -7.45724241081716 33.5325200387701 -0.222388368133237 0.82415388061204 MAMDC2 other 1 1 1 0.050227825823307 -0.222388368133237 0.724405527552154 -1.99777639787223 3.88345066387228 -0.514433314798494 0.60730752815027 -12.4094685249926 18.1270893219237 -0.68458141870488 0.494108294137228 CPA6 other 1 1 1 -0.514433314798494 -0.68458141870488 0.366677304634595 -463.249667693999 342.626300570211 -1.35205518935074 0.177312457544577 -451.539520416411 659.718287820535 -0.684442933828816 0.494190907464284 ALDH1A1 other 1 1 1 -1.35205518935074 -0.684442933828816 2.10748074102003e-13 217.757985170078 34.8161763612741 6.25450603508229 1.27622155851114e-09 -174.496965008592 82.1600414270478 -2.12386656551936 0.0344480511963843 KDM1B other 2.81580501807686e-09 1 1.69380125245598e-05 6.25450603508229 -2.12386656551936 1.01344625611663e-12 160.985519831593 73.9568037336771 2.17675063962082 0.0303754474755113 -845.11259366002 163.749665277417 -5.16100348802709 4.80023554449232e-07 HGSNAT other 1.33531678705928e-08 0.00721955425891645 1 2.17675063962082 -5.16100348802709 0.0256288002590902 4.55966371474053 27.2145130744547 0.16754529843198 0.867047171672771 -137.522319318125 52.0965747761154 -2.63975741033122 0.00870425500449796 RASEF other 1 1 1 0.16754529843198 -2.63975741033122 0.0347891687817781 -3.31231758169725 4.73159242655997 -0.70004287839843 0.484410731196608 -23.5112153244253 9.05765824235024 -2.59572780241317 0.00987555232837571 GKAP1 other 1 1 1 -0.70004287839843 -2.59572780241317 0.125787992071637 2.19195992758514 3.99554673844415 0.548600747550928 0.583663212070214 -14.0169199163746 7.64865051457441 -1.83260039005124 0.0677939942730098 KIF27 other 1 1 1 0.548600747550928 -1.83260039005124 1.60566721194225e-10 74.557506889627 13.2100899890782 5.64398175570867 3.67192687433723e-08 -74.8698362413642 25.2879939109113 -2.96068705588621 0.00329967518989436 C9orf64 other 1.99632604460779e-06 1 0.000464902661559836 5.64398175570867 -2.96068705588621 0.807312600363429 8.18753896677355 21.1075303174308 0.387896586840963 0.698350465559124 23.6197793461954 42.1489966578129 0.560387701229351 0.575607131241391 SVEP1 other 1 1 1 0.387896586840963 0.560387701229351 0.074566813257134 -5.76814609617819 14.815445175691 -0.389333295609807 0.697288572354694 -69.5156370320262 32.2968944905693 -2.15239384865083 0.0321138067031607 TRPV6 other 1 1 1 -0.389333295609807 -2.15239384865083 5.75766636543643e-06 116.480853015806 26.4426136292535 4.40504311143217 1.44441380498614e-05 -91.4344801970212 50.2941345013659 -1.81799490345217 0.069999822218003 ANKS6 other 0.0561487623957361 1 0.160243267525162 4.40504311143217 -1.81799490345217 0.163068300076265 61.4516005162564 56.8498356563678 1.08094596592511 0.280535109254565 -152.746631939587 108.450549634019 -1.40844497750405 0.159970183628271 FBP1 other 1 1 1 1.08094596592511 -1.40844497750405 0.177384634302023 67.1464224465431 47.0733946953919 1.42641980424489 0.154722079046668 -91.1057831325302 90.0847908239514 -1.01133368129337 0.31262082789231 TMEM246 other 1 1 1 1.42641980424489 -1.01133368129337 2.74556079484065e-07 161.973088314172 28.8038661081612 5.62331069398627 4.09500916657819e-08 12.8804365569832 162.874116124265 0.0790821578252256 0.937016859547664 ZHX1 other 0.0029566944199639 1 0.000517568208563818 5.62331069398627 0.0790821578252256 0.0666706175854275 13.9641152104682 6.70640021260853 2.08220725989699 0.038125219970943 -11.129028076739 23.1392461660661 -0.480958973203707 0.6308774456079 METTL27 other 1 1 1 2.08220725989699 -0.480958973203707 0.035440489342325 -16.662890341748 7.0364449812862 -2.36808365389965 0.0184820937807255 -41.2537035258512 24.7328125665356 -1.66797461529584 0.0963113375294763 NCF1C other 1 1 1 -2.36808365389965 -1.66797461529584 0.000419758665916397 3.79209728685388 3.76151491502815 1.00813033379279 0.314153579050923 -28.2221936652848 7.50774319143097 -3.75907818710374 0.000202681927461827 C9orf84 other 1 1 1 1.00813033379279 -3.75907818710374 0.0562984158461653 20.8594079061699 9.57421541574455 2.17870676607789 0.0300828051692367 -15.8680496032973 19.1605156738606 -0.828164015697399 0.408194841257452 KIAA1958 other 1 1 1 2.17870676607789 -0.828164015697399 0.0702409840123501 62.0369624190373 29.442526828367 2.10705292995663 0.0358909161953025 -44.9500739307292 58.9222168372443 -0.762871397980338 0.44610208894995 RNF183 other 1 1 1 2.10705292995663 -0.762871397980338 0.597385796698642 32.1440373168969 41.81657425478 0.768691311752363 0.442645297093261 -47.0932406360357 83.2467140072503 -0.565706901439186 0.571990733732121 STRBP other 1 1 1 0.768691311752363 -0.565706901439186 0.533130505999848 -43.0025000668362 48.8238064289689 -0.880769100405929 0.379110076351844 -151.961489573199 168.457896920656 -0.902074003955857 0.367702443877514 CLDN3 other 1 1 1 -0.880769100405929 -0.902074003955857 4.92286813738359e-10 264.048654481961 42.2443778246766 6.25050404524409 1.31456491080123e-09 -152.540577384545 82.9588260040704 -1.83875043478871 0.066884248793556 GAPVD1 other 6.026575173785e-06 1 1.74403326716e-05 6.25050404524409 -1.83875043478871 2.55244070499674e-12 135.093917870837 20.6880616961952 6.53004229466709 2.58142928724061e-10 -118.567561130474 39.4820398889123 -3.00307586599067 0.00288332508677643 CARD19 other 3.33067987595025e-08 1 3.47873410748545e-06 6.53004229466709 -3.00307586599067 0.0658644501129089 -229.136164749036 121.431892444732 -1.88695210241678 0.060071783061674 -378.345037309081 231.746158325252 -1.63258385831829 0.103540118289189 WNK2 other 1 1 1 -1.88695210241678 -1.63258385831829 7.96078701810985e-05 28.292550946003 25.2061069818102 1.12244826090836 0.262516005125422 -197.795715985284 48.316966428563 -4.09371139385845 5.38464812517497e-05 ZNF367 other 0.693066117796643 0.776089334281468 1 1.12244826090836 -4.09371139385845 3.91894754755066e-29 233.68845552803 23.8771087564882 9.78713368989991 7.03221481562986e-20 -290.377198765582 59.177025465065 -4.90692454518529 1.49951772693142e-06 NDUFB6 essential 5.91134048072542e-25 0.022413291464444 1.04344003434316e-15 9.78713368989991 -4.90692454518529 4.75141539145108e-23 561.437517866835 55.3132252148407 10.1501497279569 4.18245527506879e-21 -147.976519506172 156.871440879247 -0.943298019555245 0.346258346910635 NOL6 essential 7.02734336395614e-19 1 6.23896853382011e-17 10.1501497279569 -0.943298019555245 3.21776376014281e-05 3984.30567245215 1322.9037802502 3.01178795611167 0.00280950980398174 -8947.94678900768 3689.75427986261 -2.42507931702728 0.0158724018036253 AQP3 other 0.292945212723401 1 1 3.01178795611167 -2.42507931702728 1.74000031135511e-27 32.2270011037788 3.19878129139837 10.0747747870222 7.60629359641885e-21 -41.3946127296443 9.48058792648575 -4.36624954598025 1.72321130096562e-05 TRMT10B other 2.6150464679356e-23 0.252209206009329 1.13318561999448e-16 10.0747747870222 -4.36624954598025 7.44143753787599e-55 3461.32250662819 186.493890548967 18.5599780048525 3.8812604095251e-52 -1502.06861987236 584.289936759871 -2.57075901084648 0.0106170821207875 VCP essential 1.1414421039348e-50 1 5.95268909008865e-48 18.5599780048525 -2.57075901084648 3.30431313619463e-32 258.101021055937 21.3083792774153 12.1126537919989 6.76218969632317e-28 -245.607539976996 66.6964709786193 -3.68246679881653 0.00027257185516025 PIGO other 5.00900828315744e-28 1 1.02420125140511e-23 12.1126537919989 -3.68246679881653 4.86882110763487e-48 828.394219457175 51.1590375523802 16.1925293963751 3.97282938937571e-43 -646.179376816911 160.13077386054 -4.03532288790208 6.87945042627414e-05 STOML2 other 7.45806017267509e-44 0.987820286708703 6.07962081456165e-39 16.1925293963751 -4.03532288790208 0.575313008263217 -0.932644964311136 5.48201742694994 -0.170128055362647 0.865028877575481 9.62185001561764 10.3915058420195 0.925934139084092 0.355255443141882 SLITRK5 other 1 1 1 -0.170128055362647 0.925934139084092 1.40855514034438e-26 241.99070141278 24.1324301172167 10.0276143031338 1.11180601782005e-20 -330.436053967714 75.2764402257639 -4.38963443245579 1.55916839968241e-05 MELK other 2.11114244434815e-22 0.228386987185479 1.65525679933049e-16 10.0276143031338 -4.38963443245579 0.0021499988427771 -26.581948945295 35.2362773903831 -0.754391522429946 0.451170685905356 -231.828567355576 69.4986429466094 -3.33572797289974 0.000951143794226215 OTUD1 other 1 1 1 -0.754391522429946 -3.33572797289974 2.01778157209208e-09 114.212821413792 24.4488601373402 4.67149882539339 4.4299834029223e-06 -89.5013245861985 51.6474851966158 -1.73292705821934 0.0840842089548489 ARHGAP12 other 2.4104418660212e-05 1 0.0508783593825626 4.67149882539339 -1.73292705821934 0.191540078866306 13.1966379455989 7.85134940401442 1.68081144610013 0.0937876587060499 29.6180072647406 19.1904096165187 1.54337545975288 0.123740518054626 FAT3 other 1 1 1 1.68081144610013 1.54337545975288 0.39292669387279 10.0332060969347 10.0970157330412 0.993680346966504 0.321131645439156 -7.6666690331218 19.5805553705317 -0.391545024543071 0.695655831004987 HECTD2 other 1 1 1 0.993680346966504 -0.391545024543071 1.32136889235227e-09 51.0224022405646 8.60495771898777 5.92941928441766 8.10348995727557e-09 -34.3671023761173 24.7367919472882 -1.38931121098283 0.165735230649195 FBXO33 other 1.58921036683208e-05 1 0.000105005022866377 5.92941928441766 -1.38931121098283 1.36385238095231e-11 330.530326631722 55.9315959172562 5.909545780183 9.00639204553608e-09 -522.514801114281 178.772325068969 -2.92279468263726 0.00372342918633783 SPTSSA essential 1.7475040557142e-07 1 0.000116506687501055 5.909545780183 -2.92279468263726 1.36378229566133e-16 64.0603393563207 15.5983513083665 4.10686604564168 5.10539703396895e-05 -136.458160053121 33.0911023831269 -4.12371151837784 4.76345496697831e-05 WRN ts 1.91393207373112e-12 0.687652359032988 0.544184269850751 4.10686604564168 -4.12371151837784 6.09300654694068e-05 29.6421212888407 31.0200445078096 0.955579586011811 0.340012821725688 -242.046524045545 66.4544671769112 -3.6422912458418 0.000315544864730176 MARCH8 other 0.538317128422209 1 1 0.955579586011811 -3.6422912458418 0.0919637437602637 102.288287459906 48.5479398268148 2.10695423585015 0.0359221042598651 168.804375540211 156.701278595849 1.07723674658442 0.282209388186508 CFL2 other 1 1 1 2.10695423585015 1.07723674658442 5.79745542589113e-27 203.990598305142 26.5369920055004 7.68702791419843 1.93309334021487e-13 -291.662985399721 49.3413948888718 -5.91112160603917 8.82762498347027e-09 SUGT1 essential 8.69850212100705e-23 0.000134215210248682 2.73919326308448e-09 7.68702791419843 -5.91112160603917 3.36097754521229e-05 108.245443454471 31.2039084209502 3.46897068130721 0.00059496419652002 -198.814491545646 94.0462534100571 -2.11400756900737 0.0352977535373328 GTF2A1 essential 0.305311200207084 1 1 3.46897068130721 -2.11400756900737 0.301350644358609 35.5661139845173 29.4201133041803 1.20890472503597 0.227594724857485 -30.6421305758275 68.7414688546737 -0.445759031431347 0.656073697154728 ZCCHC24 other 1 1 1 1.20890472503597 -0.445759031431347 0.000214177086422318 61.8498027652703 22.1199600381472 2.79610825058483 0.00548888059124273 -121.253258036784 76.997493748586 -1.5747688935526 0.116310405231596 PGM2L1 other 1 1 1 2.79610825058483 -1.5747688935526 0.568914362998306 -3.62245979253587 5.90865491033016 -0.613076892712533 0.540266486903274 -13.8631865830575 13.5120840227418 -1.02598433814686 0.305683694280807 PHYHIPL other 1 1 1 -0.613076892712533 -1.02598433814686 0.314403477568645 63.0580331309202 43.3434628592542 1.45484529779459 0.146704696677216 91.6992805797985 99.1190923956171 0.925142456044657 0.355597762184284 SLC16A9 other 1 1 1 1.45484529779459 0.925142456044657 0.273884492316768 2.02360692665072 9.01293906856852 0.224522423956886 0.822503154851545 57.6305345711424 37.0378894902541 1.5559886204182 0.120761576250124 FOLR2 other 1 1 1 0.224522423956886 1.5559886204182 1.03490487231821e-26 509.87707165986 45.9057951464089 11.1070306054757 2.99515215117469e-24 -14.1050315111264 188.64587396628 -0.0747698914085322 0.940447464661762 INPPL1 other 1.55163287506669e-22 1 4.50530786579697e-20 11.1070306054757 -0.0747698914085322 6.49792503933258e-09 12609.3944949654 3001.42108425797 4.20114143966666 3.48497432758767e-05 -10560.9241896626 4875.33698449433 -2.16619368532902 0.0310657294026483 GJB2 other 7.60777063605059e-05 1 0.376690875068951 4.20114143966666 -2.16619368532902 9.51343279101442e-06 33.2558511405378 21.3576552601831 1.5570927957872 0.120478705192473 -116.011676832113 34.6921553720588 -3.34403197460454 0.000928048730748318 CRYL1 other 0.0909674443476799 1 1 1.5570927957872 -3.34403197460454 2.17043968561874e-06 138.941680161753 74.2682953866072 1.87080744802995 0.0622929360326932 -581.761560531317 152.694195066133 -3.80997823970553 0.00016691423922929 REEP3 other 0.0218650093929232 1 1 1.87080744802995 -3.80997823970553 5.91283353901256e-07 14.9326834728282 18.3339287530582 0.814483555268389 0.415995243922132 -130.100356671511 29.6740401735647 -4.38431558057306 1.59702862720301e-05 SKA3 essential 0.00621734446627171 0.233836931595065 1 0.814483555268389 -4.38431558057306 3.93704377922675e-22 104.701362564145 22.6476882841854 4.62304855358048 5.55736268926483e-06 -232.795935068697 36.6852962705051 -6.34575589500866 7.84099121821897e-10 MICU2 other 5.79099769486463e-18 1.19731935902204e-05 0.0634484098233365 4.62304855358048 -6.34575589500866 4.57648828091379e-07 27.4018457744447 12.6310979471325 2.16939539928636 0.0308098229710077 -114.720818572785 35.3358631645906 -3.24658316788322 0.00129543533274076 DDIAS other 0.00485016228011244 1 1 2.16939539928636 -3.24658316788322 1.6567970189097e-06 46.5610674553903 25.190696118279 1.84834381855785 0.0655017871716915 -229.834300514851 70.4037134010471 -3.26451957449495 0.00121870104757807 PCF11 essential 0.0168562528703873 1 1 1.84834381855785 -3.26451957449495 0.0397093277161586 25.2147337908747 9.98389707218737 2.52554023830199 0.0120360622175738 24.1348024658389 18.4877400106321 1.30544904092979 0.192680727158643 PKNOX2 other 1 1 1 2.52554023830199 1.30544904092979 0.00251834690683755 27.0126943914546 10.6503907962007 2.53631016066478 0.0116869897569921 -58.4646004613879 32.6392538074079 -1.79123581704305 0.0742184390609597 LRR1 essential 1 1 1 2.53631016066478 -1.79123581704305 1.94427643547101e-09 644.022379131444 107.582098550617 5.9863340444919 5.85845821187882e-09 -418.768198135645 329.696767650984 -1.27016167346521 0.204967432762604 RPL36AL essential 2.3239936233185e-05 1 7.63181351261453e-05 5.9863340444919 -1.27016167346521 1.03619821197996e-09 57.7989178428458 9.10344298011815 6.34912724439294 7.57664317239857e-10 -15.2850249319686 27.8984679186923 -0.547880441912275 0.584163251324181 DNAAF2 other 1.25079486168101e-05 1 1.01178492924211e-05 6.34912724439294 -0.547880441912275 0.129771429657621 -66.3027611944244 130.607176769594 -0.507650213673862 0.612056191312246 -564.354047062471 281.563834227963 -2.00435559705282 0.0458931382596452 C10orf10 other 1 1 1 -0.507650213673862 -2.00435559705282 0.0341761473954018 -38.6808575483188 29.3676183594531 -1.31712613106292 0.188753664765199 -162.984343355863 62.866033420492 -2.59256604064248 0.00997048015119106 ZNF22 other 1 1 1 -1.31712613106292 -2.59256604064248 1.22489140332221e-13 175.576797541032 22.6727147984837 7.74396886749417 1.32795956962003e-13 -36.9399880696929 69.4900887676131 -0.531586428004526 0.595387134811792 KLHDC2 other 1.64319181755674e-09 1 1.88570258886044e-09 7.74396886749417 -0.531586428004526 3.74834075370239e-06 62.8216537668468 14.164598558087 4.43511713439843 1.27183843283318e-05 -46.7789126527317 41.5567377663133 -1.12566373510318 0.261162077817426 EML5 other 0.0371085734616537 1 0.141670083033288 4.43511713439843 -1.12566373510318 3.98759458683497e-17 214.700755089023 24.2615966866495 8.84940747560801 6.46173210214387e-17 -43.5656581138519 74.3598868677188 -0.585875798753597 0.558378512533502 NEMF other 5.62809099985888e-13 1 9.43154417628919e-13 8.84940747560801 -0.585875798753597 8.84806043277425e-29 130.234938034275 18.5628172301256 7.01590369714555 1.37483575686173e-11 -126.387623215673 34.4269620401549 -3.67118141496939 0.000282947721615324 RPUSD4 essential 1.33340270721908e-24 1 1.89741082804488e-07 7.01590369714555 -3.67118141496939 5.85107868225454e-18 855.399374694115 110.18097180029 7.76358531529908 1.15766604762071e-13 -1206.97062822596 338.243487783104 -3.56834845849248 0.000414961440033035 ARF6 other 8.33895733794917e-14 1 1.64573805329761e-09 7.76358531529908 -3.56834845849248 1.45906146002025e-11 67.656231530005 9.83442731881907 6.87952936522686 3.1975497951594e-11 -13.8010285385041 28.8930149847973 -0.477659688535995 0.633220591698804 TTC8 other 1.86818229340993e-07 1 4.38384076916354e-07 6.87952936522686 -0.477659688535995 3.79438640922196e-10 174.752512977882 27.7121222412696 6.30599531340245 9.50365947138551e-10 -100.20430682963 90.3557660932971 -1.10899736853721 0.268264073408463 TMEM63C other 4.66216258101102e-06 1 1.26569736839912e-05 6.30599531340245 -1.10899736853721 0.131912551648149 13.1553456683371 6.82867234849163 1.92648658435676 0.054929068395575 -3.50848371946343 22.2649826699021 -0.157578551552443 0.874888289242699 NGB other 1 1 1 1.92648658435676 -0.157578551552443 3.45861471805549e-05 14.7513425307818 4.76045003647803 3.09872856930464 0.00211705042086042 -14.8089089980056 9.77115518848322 -1.51557402500987 0.130620453105994 AKR1E2 other 0.313834699516355 1 1 3.09872856930464 -1.51557402500987 1.98146754949367e-08 72.7745531911074 18.1929879699073 4.00014298429058 7.8787869123119e-05 -76.849511940312 32.7778898059898 -2.34455336799225 0.0196647771241365 KBTBD6 other 0.00022701673714549 1 0.825381716933795 4.00014298429058 -2.34455336799225 1.52933652189e-19 327.874998876236 57.237523378606 5.72832260242043 2.35155989646531e-08 -488.895113095427 117.16051854284 -4.172865733064 3.88600101894785e-05 NUDT5 other 2.21233821256608e-15 0.562731807553838 0.000300059042788974 5.72832260242043 -4.172865733064 2.40853417904955e-05 72.9483275178985 15.6475785486439 4.66195630788002 4.61033977189109e-06 29.0842720232627 49.7107136851607 0.585070498232351 0.558913923110886 DACT1 other 0.221946424599416 1 0.0528944282029065 4.66195630788002 0.585070498232351 0.218513055774081 -5.02057028892563 3.18599282509477 -1.57582598723407 0.116072852679343 2.63658909096301 7.41250109068908 0.355694934638843 0.722307875759255 OXGR1 other 1 1 1 -1.57582598723407 0.355694934638843 0.188729046651166 21.7620520406108 12.9488124955286 1.68062145066395 0.0938215022305539 39.1406289921335 26.4579062409859 1.47935473939737 0.140038568177645 BEND7 other 1 1 1 1.68062145066395 1.47935473939737 3.50606157475387e-15 578.473305884741 111.516102166288 5.18735227153248 3.80607992910838e-07 -781.548089015688 225.944296734474 -3.45902994813873 0.000616034033376748 ATP5C1 essential 4.83100224385335e-11 1 0.00462514832985251 5.18735227153248 -3.45902994813873 2.53074276680898e-22 77.3289854098034 12.3228778688872 6.27523750803725 1.14537798327687e-09 -110.667010970662 25.1789534667155 -4.39521885279923 1.5116461342275e-05 PRPF18 other 3.72727794695627e-18 0.221531740971041 1.52186372637997e-05 6.27523750803725 -4.39521885279923 6.77068697859649e-15 41.1476822027343 10.4816252071353 3.9256967683526 0.000106053811825242 -99.2403957788309 21.2369639007744 -4.67300298868108 4.38932344010487e-06 TAF3 other 9.29683029031084e-11 0.0651551171449167 1 3.9256967683526 -4.67300298868108 0.407631568722578 -69.4499458194412 61.4617895499632 -1.12996947091793 0.259335352254741 -142.985993784633 128.478398688684 -1.11291855474555 0.26657872849637 VSTM4 other 1 1 1 -1.12996947091793 -1.11291855474555 5.84452360117158e-08 276.801461712431 64.428054181861 4.29628777754336 2.30890399389228e-05 -322.491007223737 151.762177759931 -2.12497614348865 0.034357016376524 VDAC2 other 0.000652716395778842 1 0.252547918851937 4.29628777754336 -2.12497614348865 0.470852866794511 -9.16680120617188 31.6789621333454 -0.289365578568714 0.77249019631511 -80.2823823502537 65.881326080362 -1.21859086825795 0.223902766006818 SOHLH1 other 1 1 1 -0.289365578568714 -1.21859086825795 8.16462183384211e-12 329.519202752764 45.6618922747726 7.21650344164159 3.9184189482836e-12 116.729133214683 107.55793109471 1.08526755792557 0.278622636319591 COMTD1 other 1.05258304681892e-07 1 5.4548310179056e-08 7.21650344164159 1.08526755792557 0.00036516773461947 18.5123450304685 10.1873513885464 1.8171892108563 0.0701233717542566 -48.7843688597413 19.6506304022824 -2.48258543675399 0.0135556208193978 SLC18A2 other 1 1 1 1.8171892108563 -2.48258543675399 2.28560723368422e-05 207.906335364573 57.1108402414607 3.64040056993662 0.000317327909732276 -126.281023397957 110.162491774898 -1.14631596801564 0.252520888118015 PDZD8 other 0.211212964464758 1 1 3.64040056993662 -1.14631596801564 0.00131450049266163 115.559779667837 33.5706142118006 3.44228970428594 0.000653720962800942 8.9999129670294 79.0765697678902 0.113812637465768 0.90945791568123 ZNF503 other 1 1 1 3.44228970428594 0.113812637465768 7.60966942682544e-11 177.129476321126 25.0219402228208 7.07896648876086 9.29007486179492e-12 31.9693640758223 52.1687945937578 0.612806263299162 0.540441066998008 QSOX2 other 9.55774480009275e-07 1 1.28574636087242e-07 7.07896648876086 0.612806263299162 8.66748101049122e-09 56.4097632217782 23.9281639205321 2.35746308864821 0.019001991043322 -198.068546149326 46.5296677849529 -4.2568227021251 2.7277833118996e-05 FAM204A other 0.000100950151329191 0.396892471881392 1 2.35746308864821 -4.2568227021251 3.46732098697773e-07 249.94548606735 107.775934520814 2.31912149199764 0.0210218291323403 -655.713143569354 163.910543067222 -4.00043298801369 7.8696017130956e-05 NSD1 other 0.00371523443754664 1 1 2.31912149199764 -4.00043298801369 0.00165647575302125 106.635984575148 89.9972712358295 1.1848801981531 0.236944045059804 -452.17663107743 175.193497378377 -2.58101263941797 0.0102959648390318 PRDX3 other 1 1 1 1.1848801981531 -2.58101263941797 2.33259572675495e-10 623.958934398167 160.570332231437 3.88589178167003 0.000124088573248627 -1117.3123885736 321.105664662817 -3.47957856721977 0.000572277678082901 GHITM other 2.88845328844065e-06 1 1 3.88589178167003 -3.47957856721977 5.55543586468341e-13 123.362519384469 16.9991791482426 7.25696919296377 3.03295065958841e-12 -74.7572399925018 35.4419632270699 -2.10928608874024 0.0356987834460315 SNAPC4 essential 7.35650817201378e-09 1 4.22975298986199e-08 7.25696919296377 -2.10928608874024 0.36103293986269 5.14669300884556 3.88491925335146 1.32478763989897 0.186186850745736 -5.86165304656279 20.3550989778705 -0.287969763887438 0.773556301428137 TMEM52B other 1 1 1 1.32478763989897 -0.287969763887438 1.66672527243306e-15 395.139516385156 49.4718979329093 7.9871509462002 2.55485861600082e-14 -246.574232460294 102.493225566036 -2.40576126957217 0.0167093156346263 PMPCA essential 2.309247864956e-11 1 3.65855753811318e-10 7.9871509462002 -2.40576126957217 8.74777986111992e-18 258.273470118096 27.965272776306 9.2355069154527 3.70651440618599e-18 -47.1403191265768 58.305413498468 -0.808506728587311 0.419401480627412 SDCCAG3 other 1.24472159643875e-13 1 5.45117073717774e-14 9.2355069154527 -0.808506728587311 0.757070758786898 -9.21839917149917 12.6114177670685 -0.730956609459935 0.465342196799056 2.07067233007735 26.3966617570557 0.0784444771515046 0.937523677087018 AK8 other 1 1 1 -0.730956609459935 0.0784444771515046 0.00195313785172239 38.7064793319473 10.8582407642321 3.56470999054005 0.000419796918317825 4.94291696666685 22.7126469819146 0.217628397544449 0.827857358394066 SPACA9 other 1 1 1 3.56470999054005 0.217628397544449 6.45642336205547e-15 148.57738525412 19.2189162765287 7.73078893296248 1.39702144145293e-13 -112.868302705273 40.2010298207493 -2.80759729809253 0.0052975731108152 TSC1 ts 8.86660620311077e-11 1 1.98293223399828e-09 7.73078893296248 -2.80759729809253 1.61328032152497e-24 74.0973639912611 6.94958167560422 10.6621329815249 6.63834655079566e-23 -60.8236387730316 31.3646173103902 -1.93924377176706 0.0533531710441197 BORCS5 other 2.39943182220409e-20 1 9.9542006529181e-19 10.6621329815249 -1.93924377176706 5.98481359424921e-08 93.6647131097895 17.0115094100885 5.50596133781302 7.59378490481529e-08 102.000923401727 35.5986875278595 2.86530011315448 0.00444442954245601 FAM69B other 0.000667963805201851 1 0.000950741870082874 5.50596133781302 2.86530011315448 9.5963820979629e-12 171.41776542781 26.3479494291305 6.50592433725752 3.03415184201204e-10 -152.22278754197 55.602954170682 -2.73767446015006 0.00653922381373318 ZMYND19 other 1.23428666543999e-07 1 4.08396837934821e-06 6.50592433725752 -2.73767446015006 0.463342788105923 -21.6745838128607 22.9224127156344 -0.945562933612021 0.3450849778109 17.7067808129153 48.0134614027187 0.368787841901203 0.712529740736813 STOX1 other 1 1 1 -0.945562933612021 0.368787841901203 0.350613061177945 8.78667748482811 21.6804260785346 0.405281586856249 0.685558440987423 -50.9017070199249 44.9972262902974 -1.13121877094235 0.258863497015454 RET other 1 1 1 0.405281586856249 -1.13121877094235 3.60994593252127e-07 977.357311846226 226.286816489399 4.31910849694602 2.09268495558781e-05 -732.416966939053 473.982100586097 -1.54524182671327 0.123276123721966 DDX21 essential 0.00386119816942475 1 0.229672173875762 4.31910849694602 -1.54524182671327 6.76271383704203e-11 188.240155599536 57.8939786965653 3.25146344814446 0.00127844302993738 -553.31053367911 120.15762286306 -4.60487250409158 6.09721276418625e-06 BMS1 essential 8.51087536391739e-07 0.0902631377610133 1 3.25146344814446 -4.60487250409158 0.0359430230026247 38.7460566512188 23.3230957792117 1.66127417294893 0.0976439116647937 -49.3960658298526 47.0635757635359 -1.04956040905255 0.294717250904169 STK32C other 1 1 1 1.66127417294893 -1.04956040905255 4.1058089230582e-07 105.231359975089 23.3765862940986 4.50157087314558 9.47739832407224e-06 -148.553614665453 65.4415386597595 -2.2700201998276 0.0238753227815407 METTL17 essential 0.00436570662788778 1 0.106630208544137 4.50157087314558 -2.2700201998276 0.00303195593504044 41.1721315372465 21.4902138964513 1.91585489728631 0.0562800312337992 -144.775671847579 60.1607371503233 -2.40648101577992 0.0166770299024721 SLC39A2 other 1 1 1 1.91585489728631 -2.40648101577992 0.0923948764303092 104.321045530161 57.6014699672523 1.81108304335758 0.0710744583411795 -131.919364515218 160.678045324851 -0.821016737218272 0.412253726140067 RNASE7 other 1 1 1 1.81108304335758 -0.821016737218272 0.065408670432294 99.0258922737342 43.1370180435304 2.29561283475379 0.022350534797418 115.099417961599 120.329771867242 0.956533168604245 0.339531833813405 ARHGEF40 other 1 1 1 2.29561283475379 0.956533168604245 0.00757309363935737 64.2687158930877 36.2817307799159 1.77137954864778 0.0774583468134742 -219.583868418129 101.207097423619 -2.16964890810993 0.0307760485479261 ZNF219 other 1 1 1 1.77137954864778 -2.16964890810993 0.0120620841875333 -14.6361178888319 58.5584396587019 -0.249940366822204 0.802793841572324 -318.966452606222 113.465295366835 -2.81113667024793 0.00524105496701708 CASP7 other 1 1 1 -0.249940366822204 -2.81113667024793 0.0236075720194986 17.6934714402373 66.6890194098278 0.265313114464986 0.790941254986286 -266.343128329605 106.853417385091 -2.49260280904004 0.0131928341650459 BTNL9 other 1 1 1 0.265313114464986 -2.49260280904004 0.658457020174132 -6.9968277663743 13.6101272241182 -0.514089813501185 0.607544022550828 -23.5575625011399 26.072657804719 -0.903535139285882 0.366921607554948 VWA2 other 1 1 1 -0.514089813501185 -0.903535139285882 4.0417091741954e-09 140.770330018886 23.6415952830977 5.95434987923715 6.9058885274267e-09 -57.647610831875 65.5829713921547 -0.879002729034187 0.380063503763338 METTL3 essential 4.77770441481638e-05 1 8.97351155253826e-05 5.95434987923715 -0.879002729034187 0.457753071550613 13.723926970045 11.1028367382678 1.23607392358956 0.217343333254189 3.23807372611912 30.7998261309452 0.105132857320443 0.916336668919965 SALL2 other 1 1 1 1.23607392358956 0.105132857320443 0.0455043296471975 10.7931423054346 4.55167674385713 2.3712453482117 0.0183392142911932 15.8856262196103 9.19805646003845 1.72706335176637 0.0851523860329706 PRAP1 other 1 1 1 2.3712453482117 1.72706335176637 0.0223678142057325 44.3406703088885 24.5876836563395 1.80336915541273 0.0722707544478172 -54.1193002731665 47.4277823107372 -1.14108856953479 0.254686293250724 TRUB1 other 1 1 1 1.80336915541273 -1.14108856953479 4.32026572694451e-19 7.53040511668712 1.12332433155995 6.70367845253537 9.31266156713067e-11 -8.12131434416324 2.10304215986712 -3.86169830502893 0.000136511082254822 ERICH6B other 6.22377480623626e-15 1 1.2659618418335e-06 6.70367845253537 -3.86169830502893 6.88526612118236e-13 107.423165623609 15.473357993717 6.94245978586088 2.16354931397183e-11 -90.8345325667463 47.6540451967759 -1.9061242795164 0.0575326171324804 ZFYVE1 other 9.10163328559096e-09 1 2.97509666164267e-07 6.94245978586088 -1.9061242795164 5.89786073277114e-05 107.63400924564 26.7026403117863 4.03083769952634 6.9515762771838e-05 -3.08691472851059 51.5073737538829 -0.0599315108407733 0.952247593316988 HSPA12A other 0.521606803206279 1 0.732696139615173 4.03083769952634 -0.0599315108407733 0.0415390288631214 -12.6531147232802 8.35122671042773 -1.51512049211655 0.130729012756547 -38.2726189559235 15.2951142844281 -2.50227740991048 0.0128383022947595 FRAT1 other 1 1 1 -1.51512049211655 -2.50227740991048 2.81453145543399e-05 54.62482196266 27.0302176636429 2.02087984056944 0.0441246552526308 -137.894895631934 49.5053340824955 -2.78545530875816 0.00566387500348875 UBTD1 other 0.258008098519634 1 1 2.02087984056944 -2.78545530875816 0.359235714021234 8.68155892171054 18.0068695229738 0.482124830783847 0.630046862265508 -32.1420878313193 32.9792420692843 -0.974615722332058 0.330487074602046 ANKRD2 other 1 1 1 0.482124830783847 -0.974615722332058 0.0853166309683021 -27.6648776068518 34.2090197327776 -0.808701267179092 0.419293510343254 -177.71763510332 81.025020549795 -2.19336735612553 0.029006889014601 E2F7 other 1 1 1 -0.808701267179092 -2.19336735612553 1.96652989599499e-09 20.5774770805596 3.62015696136401 5.68413947245161 3.04248483114245e-08 -28.7690315302394 20.7111623838151 -1.38905924240743 0.165814984249466 ARHGAP42 other 2.35019987870361e-05 1 0.000386608547493271 5.68413947245161 -1.38905924240743 2.10521229561629e-21 98.0931212764289 9.73631467563096 10.0749744173682 6.45017552690365e-21 -21.6242586728631 31.7773600496756 -0.680492609803308 0.496684652527498 ISCA2 essential 3.08329392815962e-17 1 9.61205157019182e-17 10.0749744173682 -0.680492609803308 9.43208499950234e-07 502.090361172468 107.275264454989 4.68039266762317 4.28530818648244e-06 -58.2817071545448 264.43268403698 -0.220402812030582 0.825702534859816 LARGE2 other 0.00978956102098348 1 0.0492596176036156 4.68039266762317 -0.220402812030582 5.24720805506098e-05 188.299929029415 70.2411414171195 2.68076408256546 0.00772963711158972 -354.183346385396 178.070652979581 -1.98900459148656 0.0475599926326573 PACSIN3 other 0.467211405222629 1 1 2.68076408256546 -1.98900459148656 8.50147193545089e-15 144.321121319486 18.2058155065512 7.92719893638124 3.79619056264998e-14 -27.2241063657276 53.3145873314154 -0.510631474956309 0.609962307688271 TTC7B other 1.16563681706967e-10 1 5.42855250458947e-10 7.92719893638124 -0.510631474956309 4.37882192906947e-10 301.013907289747 49.8367011977269 6.04000465631695 4.30058854840818e-09 9.30623707658022 125.88798604574 0.0739247434874277 0.941116745633853 SLC39A13 other 5.36887356723208e-06 1 5.6230195270437e-05 6.04000465631695 0.0739247434874277 1.53129126699458e-08 445.249502268602 131.200422756412 3.3936590516576 0.000776930758978606 -975.620425319993 327.76757141913 -2.97656177850623 0.00313868668591192 PSMC3 essential 0.000176129121529716 1 1 3.3936590516576 -2.97656177850623 0.294937923065448 7.59738755211694 6.68198404886451 1.13699576301862 0.256396082021701 24.7493261069223 16.6930688022547 1.48261092074212 0.139168129020422 RAPSN other 1 1 1 1.13699576301862 1.48261092074212 0.0715725702525884 4.42885746372315 3.85043962979998 1.150221244724 0.250914286065914 -12.7949077826892 10.1189309508386 -1.26445252416994 0.206990699280544 AGBL2 other 1 1 1 1.150221244724 -1.26445252416994 0.441676947224935 29.9462489053225 53.2727840536373 0.562130352999222 0.574421974422974 -147.188333330674 157.134009911776 -0.9367057673467 0.349618526093036 TC2N other 1 1 1 0.562130352999222 -0.9367057673467 1.29389915511536e-20 379.691505303103 40.9435456408317 9.27353748583144 2.79961437409086e-18 -192.03713783923 120.767548023622 -1.59013858426327 0.112794085799643 CPSF2 essential 1.88611679841166e-16 1 4.12075239722434e-14 9.27353748583144 -1.59013858426327 0.372936033117322 1.60832136918983 1.30387044048752 1.23349783785916 0.218295341283163 5.89464819743388 6.70308536205211 0.879393276237388 0.379847960799174 SMCO2 other 1 1 1 1.23349783785916 0.879393276237388 0.0435229331119058 31.1663080693746 13.1161499170365 2.3761780908659 0.0180812209353532 -3.92135584177628 39.1987555639024 -0.100037763581133 0.920376988023852 MOAP1 other 1 1 1 2.3761780908659 -0.100037763581133 0.134754931798188 9.60813591961335 13.0659636279091 0.735356089549356 0.462661261273094 -62.4494188812913 39.3067453980986 -1.58877104295468 0.113099590684534 IFI27L1 other 1 1 1 0.735356089549356 -1.58877104295468 2.80026387176655e-05 2861.48757794621 1022.32087291745 2.79901120455482 0.00543698465653382 -8575.37320200932 3075.47972819199 -2.78830425165917 0.00561549095194521 IFI27 other 0.256756194402275 1 1 2.79901120455482 -2.78830425165917 0.77144290648774 -0.102105155809214 21.4992195919933 -0.00474924940285922 0.996213639379929 -44.0369313510268 63.4168453565991 -0.694404319599987 0.487935682991719 CLMN other 1 1 1 -0.00474924940285922 -0.694404319599987 0.563501481511021 3.83804204993431 3.69230388209567 1.03947079452082 0.299383036185125 4.58315990669542 9.87025840711652 0.464340417206396 0.642724626688596 PDZRN4 other 1 1 1 1.03947079452082 0.464340417206396 0.343922284937171 -11.1627238292012 11.211180348175 -0.995677839668173 0.320161353562517 11.6995497589531 23.4592441901643 0.498718102941201 0.618321697634842 NELL1 other 1 1 1 -0.995677839668173 0.498718102941201 0.000196370158235648 21.8279687112506 23.0621814728928 0.94648326035016 0.344618542223684 -139.136385398583 46.0407027633217 -3.02203000926881 0.00271415072579274 PTER other 1 1 1 0.94648326035016 -3.02203000926881 0.661215002612976 -2.10620261386672 2.49190263784771 -0.845218662188933 0.398620277380612 -3.58251822651273 4.97307559369654 -0.720382821257258 0.471815202168134 CACNB2 other 1 1 1 -0.845218662188933 -0.720382821257258 0.000114071742974886 21.3660197404157 6.47773746268529 3.29837691994985 0.0010819558981028 -9.34012178445474 12.9410442364529 -0.721744058191618 0.470978883746971 HACD1 other 0.976796335093952 1 1 3.29837691994985 -0.721744058191618 1.34670715238398e-11 297.741198638193 56.8108195797973 5.24092419085738 2.90630469709326e-07 -202.763557053744 113.37702204698 -1.78840080108759 0.0746572905956463 ARL5B other 1.72620922792579e-07 1 0.00355179497031767 5.24092419085738 -1.78840080108759 5.80052628778268e-07 93.3917092858626 17.5375812126627 5.32523317516733 1.925090770016e-07 84.9511207255655 42.6552051843612 1.99157688630019 0.0472835072941639 SMCO4 other 0.00610447386526249 1 0.00236920921065869 5.32523317516733 1.99157688630019 8.34863819494061e-11 55.0454858563882 13.2019659741874 4.16949157148366 3.95648688083577e-05 -69.7313695990047 31.3056717855104 -2.22743565692398 0.0266289271735186 CEP295 other 1.0470027160275e-06 1 0.425797118115546 4.16949157148366 -2.22743565692398 7.96404167121496e-08 124.955526579985 26.5183067316243 4.71204771272104 3.66728668435822e-06 -92.510286327611 68.3062472045292 -1.35434590705309 0.176584585559861 ABTB2 other 0.000883371502171163 1 0.0423498266309687 4.71204771272104 -1.35434590705309 4.05157698737133e-06 29.1522511361099 16.4994903379718 1.76685767493188 0.0782052750070148 -103.058075530044 30.2185055087758 -3.41042926494543 0.000731736458678158 R3HCC1L other 0.0399728585574055 1 1 1.76685767493188 -3.41042926494543 1.88624227871106e-21 1035.95476741472 171.035129842456 6.05697068414518 3.96151093753648e-09 -1368.78495807115 403.340296897131 -3.39362312320667 0.000778182337535015 AMOTL1 other 2.76353356253957e-17 1 5.18482551504774e-05 6.05697068414518 -3.39362312320667 0.0322426550931839 912.138777771639 420.522970406308 2.169058153685 0.0308142897454843 -354.044767617339 837.826364584534 -0.422575348047092 0.672888918453775 HTRA1 other 1 1 1 2.169058153685 -0.422575348047092 0.69528663988638 -3.38564330808272 5.2577036201661 -0.643939550928084 0.520077334430771 -7.84478390986976 10.4007312440017 -0.754253112192859 0.451253658324343 LIPC other 1 1 1 -0.643939550928084 -0.754253112192859 3.25823990065102e-12 123.786571023728 26.4771003878909 4.67523139657471 4.3605182943791e-06 -127.834069716562 61.7069710817193 -2.07163092719735 0.0391135491554642 CEP57 other 4.24092505468737e-08 1 0.0501023552024159 4.67523139657471 -2.07163092719735 0.00159857402553574 30.7720113098729 11.3100505332752 2.72076691605743 0.00686924457917258 -60.8798196218073 30.8650738953677 -1.97245014958297 0.0494188815374272 TCP11L2 other 1 1 1 2.72076691605743 -1.97245014958297 0.0672160946943521 92.2185503185764 48.0564727094411 1.91896211101776 0.0558811993651398 -51.083355424936 96.8625979542703 -0.527379571721305 0.598296612704348 SPRED1 other 1 1 1 1.91896211101776 -0.527379571721305 0.00678454103449543 132.166041783307 43.9924069496246 3.0042921255627 0.00287214175207026 18.0401201967645 88.1640590064015 0.204619891598397 0.837999196967574 GPR176 other 1 1 1 3.0042921255627 0.204619891598397 0.0987280017449157 63.8523017258297 33.5274296514811 1.90447947813408 0.0577946474021955 25.8205580520169 61.2409763868572 0.421622246662257 0.673599723583645 JAM3 other 1 1 1 1.90447947813408 0.421622246662257 0.00191235206839097 17.7665904271249 7.0958509624973 2.50379982908662 0.0128141670951555 -5.0495246750551 12.9598230508272 -0.389629137315481 0.697085425780616 GLB1L3 other 1 1 1 2.50379982908662 -0.389629137315481 2.71463058722291e-07 293.789885644385 56.2332743753682 5.2244847718324 3.17124421972577e-07 173.234761975989 102.742290928771 1.68610958943955 0.0927586061891342 ADAMTS15 other 0.00292447153161524 1 0.00386542957942374 5.2244847718324 1.68610958943955 0.00885421528757082 145.612398239227 85.4198458232837 1.70466706929522 0.0892715298745398 -355.825924900789 230.931751892641 -1.54082720104341 0.124392292227007 GPT2 other 1 1 1 1.70466706929522 -1.54082720104341 2.90072234484121e-17 177.884585234533 21.1016197749402 8.42990192846642 1.26945681172338e-15 -78.3283535925321 62.7076757203412 -1.24910312322617 0.212557729502585 AMN other 4.10075117890201e-13 1 1.83830040905663e-11 8.42990192846642 -1.24910312322617 0.19882326542612 19.0942903424193 30.1759207339291 0.632765790670645 0.527338495682342 -79.8990821875787 59.0491406609977 -1.35309474944404 0.176980500593088 RAB8B other 1 1 1 0.632765790670645 -1.35309474944404 0.282217772110192 48.320473905393 31.0491311848418 1.55625848651711 0.120638155613026 -7.30936610657984 76.1435268862648 -0.0959945829341186 0.92358515122344 IKBIP other 1 1 1 1.55625848651711 -0.0959945829341186 2.3403876756922e-08 54.612078926791 11.7960033586119 4.6297103575272 5.33660618927854e-06 -40.9005041763757 23.5512512994539 -1.73665949449251 0.0834126490177403 RPUSD2 other 0.000267014829919723 1 0.0610187551682108 4.6297103575272 -1.73665949449251 1.02772313950562e-08 135.255941507154 51.5768751869108 2.62241442539891 0.00914853284126482 -364.62546221528 94.466099837019 -3.85985515274117 0.000137257610377829 HIF1AN other 0.000119185052488467 1 1 2.62241442539891 -3.85985515274117 7.60208033641218e-05 70.5591026625367 64.8170588209965 1.08858846646217 0.277154565370201 -394.654133682808 118.716279874204 -3.32434720916961 0.000989119810879391 NDUFB8 essential 0.663585592565419 1 1 1.08858846646217 -3.32434720916961 0.000436268866879943 26.8201988723326 31.3718558141935 0.854912729141078 0.393241066699073 -200.710427054932 62.6353212650535 -3.20442879514558 0.00149013435234291 ZFYVE19 other 1 1 1 0.854912729141078 -3.20442879514558 0.000136788003149249 172.809245340507 288.365034485779 0.599272535412158 0.549416520643237 -2087.04527289372 575.73376224856 -3.62501803740438 0.000336181665999259 SPINT1 other 1 1 1 0.599272535412158 -3.62501803740438 0.375732281925575 504.999546873284 398.376511350818 1.26764388081247 0.205852572242571 -84.7933844967487 816.079233482183 -0.103903372390617 0.91731152897447 FBN1 other 1 1 1 1.26764388081247 -0.103903372390617 0.6227547377719 -5.7041161881728 6.29206349329102 -0.906557315299643 0.365327347352349 4.82737278680696 21.1416712397008 0.228334493147443 0.819532967541207 AVPR1A other 1 1 1 -0.906557315299643 0.228334493147443 0.874624686596547 0.207172983008439 0.99298097226346 0.20863741480987 0.834864039611655 -1.10472413932276 2.50623064692343 -0.440791090268921 0.659661879341808 DEPDC4 other 1 1 1 0.20863741480987 -0.440791090268921 8.18338688160299e-27 278.795409286587 39.5801931021575 7.04381124586758 1.19346162696068e-11 -571.93672954652 104.877113025537 -5.45339886889581 1.00451054084781e-07 BRD7 other 1.22734436450282e-22 0.00151841813354556 1.64936396845967e-07 7.04381124586758 -5.45339886889581 0.248004193786935 133.377682150437 214.036877873882 0.623152811213344 0.53363217441645 -816.096341905564 630.343812411797 -1.29468446558244 0.196371336418457 CKB other 1 1 1 0.623152811213344 -1.29468446558244 1.86810878745397e-09 148.704491865127 24.6436338530265 6.03419498731372 4.45505227326915e-09 -44.3439174165152 72.5761012256509 -0.610998891751469 0.541638169327879 TRMT61A other 2.23388448803746e-05 1 5.8214168054808e-05 6.03419498731372 -0.610998891751469 6.97760934180144e-12 103.811838888742 26.6863885394691 3.89006698059593 0.000121922647210435 -191.272606850053 48.877700227538 -3.91328982254956 0.000111253750541301 BTRC other 9.01297798680493e-08 1 1 3.89006698059593 -3.91328982254956 3.51984046278688e-07 28.161029983814 17.922855385 1.57123568643993 0.117116121510219 -134.392330117056 32.8761700259177 -4.08783413673518 5.51191175742503e-05 POLL other 0.00376869318350591 0.793935769539501 1 1.57123568643993 -4.08783413673518 2.05084254310317e-15 227.037903796276 31.1076748099886 7.29845304038522 2.35789585271641e-12 -210.490759685914 91.612859100611 -2.29761151166288 0.0222349625105811 BAG5 other 2.83836607965478e-11 1 3.29421629583009e-08 7.29845304038522 -2.29761151166288 0.0670587692123596 2.5023563182414 26.0384126119388 0.0961024911746754 0.923499329000426 -97.6105833117231 47.7626617994999 -2.04365878353843 0.0418058031858154 DPCD other 1 1 1 0.0961024911746754 -2.04365878353843 0.723986240956916 4.21487167680478 25.5991166405166 0.164649106295088 0.869324458264495 -33.4220003392872 49.823597808225 -0.670806642023949 0.502829100590027 LARP6 other 1 1 1 0.164649106295088 -0.670806642023949 7.12108446137314e-15 236.027893934876 69.6945584968529 3.38660433505055 0.000799146842448413 -884.546837239056 165.492657213928 -5.34493102068951 1.7602715705021e-07 API5 other 9.77368842323463e-11 0.00265624979988766 1 3.38660433505055 -5.34493102068951 0.0177898398176939 33.2227369139819 27.6687437921178 1.20073166904839 0.230815298449877 -175.686067984516 84.0009097984158 -2.09147815667859 0.0373374124604471 ASPG other 1 1 1 1.20073166904839 -2.09147815667859 2.61640992933862e-11 84.0646777041697 17.6181990988909 4.77146825463345 2.78838161091404e-06 -129.953582190262 46.5591534156161 -2.79115002436181 0.00556853752394181 ZNF319 other 3.33199804501273e-07 1 0.0324260309874745 4.77146825463345 -2.79115002436181 4.49915528691254e-13 87.7432878832685 24.7915559910709 3.53924085744642 0.00046094881018409 -214.665638654457 45.4833921178414 -4.71964883573959 3.54151732448342e-06 HPS6 other 5.96947923467556e-09 0.0526588210977439 1 3.53924085744642 -4.71964883573959 0.0109938766499498 5.36120827714091 2.57148085004876 2.08487194335484 0.0378733500371136 -6.44003919420094 5.06995876871125 -1.27023502320078 0.204923727180461 SENP8 other 1 1 1 2.08487194335484 -1.27023502320078 5.39384682559738e-10 662.893233959583 177.350600764465 3.73775578488146 0.00021998366068914 -1109.70957596079 325.882720570902 -3.40524214974249 0.000745551824503188 NOLC1 essential 6.59235959024512e-06 1 1 3.73775578488146 -3.40524214974249 4.10770860302377e-09 59.8309002770291 17.4501373809381 3.42867789352686 0.000688837432508489 -132.845610235542 41.4360843400699 -3.20603677570654 0.00148663227078813 ALKBH3 other 4.85449002705349e-05 1 1 3.42867789352686 -3.20603677570654 4.21090593778124e-07 265.756939999118 56.1460668310828 4.73331356938423 3.33401459673108e-06 -116.197505671137 114.203730280379 -1.01745805838271 0.309711476737954 COPS2 essential 0.00447450864948635 1 0.0386012210009525 4.73331356938423 -1.01745805838271 0.78924277844308 10.672110552764 19.3375338935271 0.551885809820676 0.581414215833377 25.6633165829147 43.1653838705344 0.594534654432507 0.552577328974907 GABRB3 other 1 1 1 0.551885809820676 0.594534654432507 1.62378615673668e-06 261.233129590472 92.1475418324761 2.83494409504046 0.00487489456531174 -664.762281380831 212.573606891664 -3.12720986909547 0.00192681295791828 SGPL1 other 0.0165366382202063 1 1 2.83494409504046 -3.12720986909547 2.34451053443458e-27 190.678515600561 15.7908404190387 12.0752607550047 7.80676131165638e-28 -80.8564720209941 91.1888497384291 -0.886692531520324 0.375923064417461 FRS2 other 3.52192372482763e-23 1 1.18233400065036e-23 12.0752607550047 -0.886692531520324 2.02058740411447e-76 1574.15543976846 62.3252623442032 25.2571009019567 1.30910455206655e-77 512.10869075661 359.915548000941 1.42285792764716 0.155770063293699 CCT2 essential 3.10342019397942e-72 1 2.01065368151901e-73 25.2571009019567 1.42285792764716 4.97207926278726e-07 194.416068083751 41.9433833426513 4.63520232727754 5.19968933366194e-06 -107.845759465313 96.7584821589322 -1.11458713550477 0.265863788946765 PCBD1 other 0.00525747661247125 1 0.0595000450450936 4.63520232727754 -1.11458713550477 0.71651318336462 -3.06348772903799 4.49594695685158 -0.681388761575446 0.496121440568457 -8.18623890353844 13.2759767956552 -0.616620458859006 0.537926279058601 C16orf71 other 1 1 1 -0.681388761575446 -0.616620458859006 0.000760006872519751 193.124134278017 69.826263000749 2.76578075323815 0.00600845574022534 -38.1984179210479 127.717394952909 -0.299085476454731 0.765068972809072 CLMP other 1 1 1 2.76578075323815 -0.299085476454731 0.148061878215116 -5.41931485869579 7.96940891942799 -0.680014655225493 0.496986830213082 -27.0120283837789 14.576637825984 -1.85310417300949 0.06478783075 SCN3B other 1 1 1 -0.680014655225493 -1.85310417300949 0.00269515420491974 83.8039934963979 24.7493904404102 3.386103334471 0.000798450608589295 -27.5019460320338 58.7703655919842 -0.467956014140991 0.640138624787893 COX11 essential 1 1 1 3.386103334471 -0.467956014140991 2.58485213406517e-19 47.6431513903193 9.43781770517698 5.04811100178226 7.50253141541221e-07 -58.5593889461034 17.2624660055589 -3.39229568517302 0.000780102980636927 ZNF202 other 3.72942465902922e-15 1 0.00899178390137153 5.04811100178226 -3.39229568517302 9.79178845898524e-05 19.8320213835371 7.72497382856047 2.56726065662708 0.0107089694403982 -37.3221227596652 15.7244227196631 -2.37351306467961 0.0182155099562015 FAM227B other 0.844933426125836 1 1 2.56726065662708 -2.37351306467961 0.0364758196430791 17.1960121042953 7.80108764048424 2.20430956512468 0.028223089810886 -21.5141977372122 18.6659818449681 -1.15258859222624 0.249950444715907 STXBP4 other 1 1 1 2.20430956512468 -1.15258859222624 0.114812971332322 6.67453416149085 17.3019685867805 0.385767326302425 0.699988126301902 61.9749741200829 30.4728166334537 2.03377898622097 0.0430010748884697 CYYR1 other 1 1 1 0.385767326302425 2.03377898622097 3.67581775070832e-23 197.47164936397 32.8219521412873 6.01645046930546 4.94542712386709e-09 -201.186885591422 60.4686010922169 -3.32712981543272 0.000981301498175005 CUL5 other 5.43873994394804e-19 1 6.45328785393416e-05 6.01645046930546 -3.32712981543272 1.71394935437859e-09 187.490249390587 61.7345826139085 3.03703761250257 0.00258560659490256 -445.959778736173 113.607733526777 -3.9254350464712 0.000106032623099933 WBP1L other 2.05279714173924e-05 1 1 3.03703761250257 -3.9254350464712 0.0275671595157062 -9.90834169782684 15.1468272409304 -0.654152948351594 0.513483107130958 -73.5851983396026 27.874112695079 -2.63991177565246 0.00869909109598341 BORCS7 other 1 1 1 -0.654152948351594 -2.63991177565246 0.909612376011876 21.9346378018318 53.8087603170547 0.407640645734773 0.683810951365894 1.85740238113261 123.824711826006 0.0150002560372808 0.988041353162758 C2 other 1 1 1 0.407640645734773 0.0150002560372808 0.00010073404677897 144.238862523872 36.2639654944973 3.97747076352583 8.71202414927239e-05 -66.8898460953959 96.0426993838913 -0.696459455268236 0.486673305046088 PLEKHF1 other 0.867622344907265 1 0.909448200942545 3.97747076352583 -0.696459455268236 1.05851264769001e-07 280.725950785141 71.6255429891146 3.91935528960395 0.000108683121182101 -429.112962135979 166.129686777086 -2.58299988677981 0.0102394807492444 ANAPC16 other 0.00116626923522485 1 1 3.91935528960395 -2.58299988677981 0.113432101687654 27.7052897042268 32.3624771884066 0.856092985185689 0.392586931031181 -81.5284746373849 64.5611292241182 -1.2628105427705 0.207576684353957 SMPD1 other 1 1 1 0.856092985185689 -1.2628105427705 0.256815339722401 32.4995912129653 23.8756271932994 1.36120366388055 0.174407076620224 70.310675525815 47.6303913189214 1.47617253561979 0.140880912096655 APBB1 other 1 1 1 1.36120366388055 1.47617253561979 0.397019392948902 35.1243466368304 55.7600867357965 0.62991915352028 0.529196997136139 -116.768726979992 131.483145476057 -0.888088937614102 0.37515994841005 SYNPO2L other 1 1 1 0.62991915352028 -0.888088937614102 1.39515210493419e-06 8.25663716814153 1.80042385945023 4.58594076322825 6.49329695732255e-06 -3.30196803592657 4.2120431657467 -0.78393499448888 0.433658127390664 NUDT13 other 0.0142947284671558 1 0.0738482662956293 4.58594076322825 -0.78393499448888 2.61697983624665e-08 2.74015165413072 0.832954943412995 3.28967572111773 0.00111628906993928 -2.86559041154529 1.52944326534503 -1.87361667900694 0.061906054966041 C11orf65 other 0.000297864644961593 1 1 3.28967572111773 -1.87361667900694 4.97986793966799e-20 524.906892089268 63.894847867616 8.21516772646246 5.60220716298448e-15 -370.977818476278 167.221843681335 -2.21847702614277 0.0272372683791455 TRIM44 other 7.22927428801602e-16 1 8.06829875613024e-11 8.21516772646246 -2.21847702614277 3.02496067129696e-13 404.927169873024 75.9025869374339 5.33482699617081 1.81301707783285e-07 -393.351493435299 151.420940219867 -2.59773511420641 0.00981785415280333 ILK og 4.02803762989903e-09 1 0.00223363703989007 5.33482699617081 -2.59773511420641 6.91571564037561e-15 534.425443533932 91.637877701211 5.83192733114627 1.33993811289053e-08 -478.984999612175 182.81186664571 -2.62009796410235 0.00920956945481228 TAF10 essential 9.4932028595436e-11 1 0.000172409836985625 5.83192733114627 -2.62009796410235 1.31342527380598e-07 571.354412069908 138.513957518063 4.12488692336583 4.7334060623806e-05 -429.453465361063 276.326730447917 -1.55415100328851 0.121136822239638 TPP1 other 0.0014392514150366 1 0.506474448674725 4.12488692336583 -1.55415100328851 0.156451403677882 -31.3349066393305 43.5918893099722 -0.71882423853013 0.472773775166993 106.607027258757 86.9631079994325 1.22588796227767 0.221142230172621 DCHS1 other 1 1 1 -0.71882423853013 1.22588796227767 0.0130406210185654 1.27766196453564 1.28158998126608 0.996935044134353 0.319549289451823 -6.72910800697599 3.02200896397256 -2.22670021406233 0.0266629899104829 MSS51 other 1 1 1 0.996935044134353 -2.22670021406233 0.00150557375647698 336.044373294998 112.003536681327 3.00030144807939 0.00291172119707316 47.5259689130426 169.898215073872 0.27973200832262 0.779866131312717 CYB5A other 1 1 1 3.00030144807939 0.27973200832262 0.0678941526760268 11.8384035293414 52.1496056755186 0.227008495577156 0.820562089361223 -254.510562252736 122.969575388973 -2.06970351363479 0.0392822836621638 USP54 other 1 1 1 0.227008495577156 -2.06970351363479 0.00141456904793775 35.1705834590188 10.3629874283832 3.39386530207399 0.000777519065967495 67.7913456614107 25.998840445101 2.60747573741062 0.00955685874778184 RAG1 other 1 1 1 3.39386530207399 2.60747573741062 6.5233406574758e-12 57.9104785146605 8.14196856160769 7.11258930521167 7.78164476611899e-12 14.2470727504024 20.356935593461 0.699863330853137 0.484532482389709 C11orf74 other 8.43141779978747e-08 1 1.07845814813643e-07 7.11258930521167 0.699863330853137 3.51870771396386e-19 81.6546648801666 19.9733110595335 4.08818871527022 5.54453276676752e-05 -128.215645305904 29.5109809823005 -4.34467581348119 1.89258693634293e-05 ATP9B other 5.0725690404503e-15 0.276525877269065 0.588718489175375 4.08818871527022 -4.34467581348119 3.14358356081558e-05 -106.232165879489 61.4352253063023 -1.72917353765431 0.0847424460046757 -563.22849675381 122.559453555486 -4.59555326345201 6.21873519909491e-06 PPFIBP2 other 0.286540989639744 0.0920248434762065 1 -1.72917353765431 -4.59555326345201 0.00158944232347568 61.0262032489138 65.359177059573 0.933705196338231 0.351159974777285 -341.955967871434 130.387493255206 -2.62261325326754 0.00914331085429852 CYB5R2 other 1 1 1 0.933705196338231 -2.62261325326754 0.497771442705242 79.3798690516701 86.073436809137 0.922234222245481 0.357103387351272 -3.8581590274288 139.678665148521 -0.0276216773930823 0.977981163858455 SERPINB7 other 1 1 1 0.922234222245481 -0.0276216773930823 8.75567745078736e-10 125.964886147202 21.270252216225 5.92211530294484 8.19674898174137e-09 -93.827219759616 63.5690390255753 -1.47598927399024 0.140930079651407 KIAA0355 other 1.06153833413346e-05 1 0.000106180686309478 5.92211530294484 -1.47598927399024 1.51970576378304e-11 47.5816185608322 50.6971173783716 0.938546825171791 0.348671315790011 -428.210391755262 82.2802509658348 -5.20429126951821 3.48755602822664e-07 SERPINB8 other 1.94491943648953e-07 0.0052519106229065 1 0.938546825171791 -5.20429126951821 0.553205041361333 20.178819171483 18.5809914472676 1.08599259779813 0.278299667368002 22.0633195393913 37.0679223025924 0.595213277919499 0.552121593302963 TUB other 1 1 1 1.08599259779813 0.595213277919499 0.293377053818162 -8.06661027501925 6.84453177810668 -1.1785481515071 0.239453760194034 -20.1426436152704 13.6544152053734 -1.47517438955157 0.14114886680234 RIC3 other 1 1 1 -1.1785481515071 -1.47517438955157 0.0128960457954624 7.83709207770725 2.88245691234874 2.71889305409297 0.00690737929178374 1.49807922502362 5.75032226728816 0.260520916113821 0.794629545003977 LMO1 other 1 1 1 2.71889305409297 0.260520916113821 2.68235420221497e-05 231.968435276965 69.1237068688342 3.35584484375436 0.000886475585377661 -234.961823541132 134.107048509906 -1.75204678763605 0.0807236102547466 IDH3A other 0.24618646867929 1 1 3.35584484375436 -1.75204678763605 0.822744782117657 -10.0935025474181 94.6949656309701 -0.106589642650623 0.915181957763805 -114.980596648456 187.339245123854 -0.61375605828047 0.539816706498366 WDR72 other 1 1 1 -0.106589642650623 -0.61375605828047 0.703953144237585 57.9674487432587 145.709072299166 0.397830058407356 0.691020721137964 -151.503199701208 282.690476427094 -0.535933157763385 0.592377059614844 CRABP1 other 1 1 1 0.397830058407356 -0.535933157763385 1.28022878763296e-10 677.988320138043 112.135308635734 6.04616269742881 4.24634678924207e-09 -534.735519020216 330.731684842853 -1.61682579422136 0.106929727280044 PLD4 other 1.59465297787561e-06 1 5.55294769629185e-05 6.04616269742881 -1.61682579422136 1.83350358360069e-35 166.397048429632 13.5745434539981 12.2580217149494 1.64820228576812e-28 -64.8374936924185 46.3824021566512 -1.39788994699838 0.163129692317384 XRRA1 other 2.79004240316517e-31 1 2.49801538431016e-24 12.2580217149494 -1.39788994699838 8.08662719277761e-05 19.7475802952071 11.0584628209225 1.78574369828734 0.0750876222933402 -58.9350783298846 22.0609455526305 -2.67146656018366 0.00793841614339188 TRIM66 other 0.703213100683941 1 1 1.78574369828734 -2.67146656018366 9.86370348126881e-32 251.045671107048 22.4847133894269 11.1651710546197 1.30486937617634e-24 -137.810231899571 76.9855556828339 -1.79007906973255 0.0744015393759716 RNF169 other 1.49425244037741e-27 1 1.96474181970872e-20 11.1651710546197 -1.79007906973255 0.022452357405381 855.583565503405 598.587314690994 1.42933795037918 0.153882609019932 -1664.81373409137 1194.14446399447 -1.39414768002397 0.164240260297402 RPL27A essential 1 1 1 1.42933795037918 -1.39414768002397 1.99611034249867e-06 450.740631522023 154.188355753855 2.92331174632657 0.00371014604747829 -738.213628230912 309.068699056456 -2.3885098377305 0.0174961759029484 ST5 other 0.0201667027902641 1 1 2.92331174632657 -2.3885098377305 0.385452287297761 27.7366288548783 20.6632838487782 1.34231466101252 0.180448492032932 16.7976939794783 52.7840943290402 0.318234009562929 0.750515672374239 CDYL2 other 1 1 1 1.34231466101252 0.318234009562929 0.273039423524702 7.78963392763201 5.35534693614052 1.4545526219905 0.146782579871895 -9.11626067681184 23.4159522251302 -0.389318383859196 0.697302040352194 TMEM130 other 1 1 1 1.4545526219905 -0.389318383859196 0.00817485190270897 39.1234758669737 30.981084978234 1.26281813223973 0.207576839479574 -155.390087300146 79.140785359913 -1.96346405451336 0.0504606382054628 CENPN essential 1 1 1 1.26281813223973 -1.96346405451336 0.000257225711459393 35.0684125815454 29.2303549595049 1.1997258545142 0.231136111975923 -168.94801101827 58.8470917416944 -2.87096619421494 0.00436579587541023 AKIP1 other 1 1 1 1.1997258545142 -2.87096619421494 3.80572597959063e-22 219.549548062988 35.4845647970082 6.18718446510294 1.87747051733409e-09 -452.248340200702 90.6448669619843 -4.98923276472314 9.98162742261149e-07 ATMIN other 5.59860348857577e-18 0.0149584668555256 2.4805140475018e-05 6.18718446510294 -4.98923276472314 0.281818363440337 3.04501645028374 2.01571343120455 1.51063955974342 0.131870211342429 1.21821736517606 5.14911418106012 0.236587755163209 0.813128466115536 C16orf46 other 1 1 1 1.51063955974342 0.236587755163209 4.43390987654413e-11 96.903958772546 29.4794080435126 3.28717451278236 0.00112517823067442 -237.857024261906 59.6110644193103 -3.99014891914688 8.20162069943142e-05 TMEM41B other 5.6119997307419e-07 1 1 3.28717451278236 -3.99014891914688 0.394856085255804 2.96562290840957 3.58727188003101 0.826707037433677 0.409021058611985 12.3950496316702 9.22319730882955 1.34389943277091 0.179935954652046 PKD1L2 other 1 1 1 0.826707037433677 1.34389943277091 1.73326208602557e-12 149.494253364269 26.2073214696811 5.70429349436634 2.68622683397976e-08 -158.772756646511 54.575949639847 -2.90920740169014 0.00388038848937532 LEO1 other 2.2707466589021e-08 1 0.000342171574112342 5.70429349436634 -2.90920740169014 2.40212476956604e-09 35.1784678357408 11.081057369418 3.17464901254169 0.00164749222991965 -76.8103780267742 22.4153847592442 -3.42668122148103 0.000691565209371372 ZNF143 other 2.86525442513838e-05 1 1 3.17464901254169 -3.42668122148103 1.20594605623109e-17 180.971774387374 46.4198391343602 3.89858684911767 0.000117971523582077 -281.394247086362 69.8903948532872 -4.02622202488712 7.08742414847875e-05 TMX3 other 1.71352875129875e-13 1 1 3.89858684911767 -4.02622202488712 2.8909796472186e-05 398.007765494892 93.0894699313463 4.27554014206358 2.51976989670382e-05 349.111766749673 173.684561438039 2.01003338384925 0.0452665898112876 MFAP4 other 0.264678754505025 1 0.274982488827288 4.27554014206358 2.01003338384925 2.20648584472301e-05 216.45957320455 97.1265181799143 2.228635158151 0.0265390862042457 -501.063380193362 196.472972095337 -2.55029165004041 0.0112332818491459 WEE1 essential 0.204144070353773 1 1 2.228635158151 -2.55029165004041 2.26715433397612e-20 162.571564777815 17.4117315281808 9.33689820077306 1.7276732552269e-18 -122.339758741753 32.3848115033895 -3.77768938778443 0.000188723407890351 MAPK7 other 3.29848284050186e-16 1 2.54641761087893e-14 9.33689820077306 -3.77768938778443 0.0278408552599911 -41.1164248506112 15.2894324527749 -2.68920543503555 0.00754117505137371 -30.2878548481104 50.6112154540058 -0.598441562337804 0.549972689995764 PRKCB other 1 1 1 -2.68920543503555 -0.598441562337804 1.21838788220773e-08 68.4150631919452 20.5090820309987 3.33584229116342 0.000950441935687983 -170.800898948596 47.9909086842382 -3.55902614956513 0.000428629544080301 NDST2 other 0.000140772535910281 1 1 3.33584229116342 -3.55902614956513 8.76974520676305e-06 887.688941693711 194.07364946928 4.57397974491237 6.86608318459512e-06 -686.092502305826 850.785301466995 -0.806422608762526 0.420601884119095 MCM7 essential 0.0841193960232712 1 0.0779712406442622 4.57397974491237 -0.806422608762526 0.000232004412459804 21.2876630178229 12.1922859811386 1.74599439766708 0.0817745884872115 -35.4287097761057 18.5561720442994 -1.90926823115922 0.0571244654777141 CCDC68 other 1 1 1 1.74599439766708 -1.90926823115922 0.421162752941703 -2.98755343380017 2.32981441817077 -1.28231390899616 0.200660701660689 1.27564753260656 12.3325359955255 0.103437568158681 0.917680491064294 CLEC4E other 1 1 1 -1.28231390899616 0.103437568158681 7.77326543356235e-13 153.657484369041 20.3275266663794 7.55908413703781 4.4044435272746e-13 -29.0232690374102 87.4506649757292 -0.331881627720786 0.740197964068978 ZNF3 other 1.02645970050191e-08 1 6.20762270734082e-09 7.55908413703781 -0.331881627720786 1.42742385359961e-12 38.1741906886616 5.15021484374733 7.41215499679735 1.13250008363072e-12 -12.0768318648634 22.1684229182661 -0.544776320326895 0.586289198152219 ZSCAN21 other 1.87477848931773e-08 1 1.5888976173339e-08 7.41215499679735 -0.544776320326895 3.28577033725772e-12 112.639628345533 15.681216967822 7.18309226743505 4.81095762597776e-12 -109.765835835324 83.0062562927856 -1.32238027273691 0.18698591267804 RIMKLB other 4.27643009394092e-08 1 6.68771219587168e-08 7.18309226743505 -1.32238027273691 0.209528007838962 552.298727960933 545.581186625713 1.01231263375625 0.312153403580169 -3713.80152117784 2887.95518220969 -1.28596231134593 0.199385940357293 A2ML1 other 1 1 1 1.01231263375625 -1.28596231134593 0.00919065148178701 7.98879443639656 3.90105960031064 2.04785244392585 0.0413903916585692 -13.0009745786934 10.3429739311854 -1.25698611107331 0.209675358271951 BEAN1 other 1 1 1 2.04785244392585 -1.25698611107331 0.0641492076478249 38.6275246677161 17.485038561614 2.2091758351919 0.0278704645601589 7.94580561686368 46.3585068052136 0.171399084320164 0.864018307581038 TK2 other 1 1 1 2.2091758351919 0.171399084320164 0.000439195375035306 398.470976969976 142.846955708124 2.78949575785264 0.00559536675666042 -452.027036189507 279.030881770607 -1.6199892761731 0.106219591905964 TMED3 other 1 1 1 2.78949575785264 -1.6199892761731 4.31326556150226e-08 76.8392638759222 50.7181103880686 1.51502615708645 0.130752893668064 -279.712745746175 76.8260916293512 -3.64085611820075 0.000316789363301832 SEC11C other 0.000484897314424084 1 1 1.51502615708645 -3.64085611820075 1.80703298420002e-15 44.6268056625579 9.22820618180646 4.83591337074157 2.07632439969269e-06 -76.5728822730938 23.0765366022771 -3.31821380273926 0.00101206362057406 TMEM135 other 2.50292138641544e-11 1 0.0243155913168868 4.83591337074157 -3.31821380273926 0.553062258674392 -5.44648888731995 6.50156474983293 -0.837719702393167 0.402813383708435 -13.9612723648269 17.3248466461584 -0.805852579821977 0.420926279752524 IQCD other 1 1 1 -0.837719702393167 -0.805852579821977 0.000567377433540961 302.21122610848 77.5132160889419 3.89883482271862 0.000117856312472589 -29.2552006334792 146.375363742115 -0.199864238663968 0.841714105498008 NDEL1 other 1 1 1 3.89883482271862 -0.199864238663968 6.07622500681947e-09 116.737659824015 18.7337004519158 6.23142555970982 1.45568636822547e-09 -25.5296677027945 39.8341711568977 -0.640898679735019 0.522047219578991 CENPV other 7.12498144299651e-05 1 1.92805659471464e-05 6.23142555970982 -0.640898679735019 0.0388272696007969 119.900933623776 48.8020612580983 2.45688256874354 0.0145453092090528 219.175957203192 131.468506665643 1.6671365847382 0.0964655908498714 CDH16 other 1 1 1 2.45688256874354 1.6671365847382 0.000489008777237758 568.197097007265 179.563021368464 3.16433245930588 0.00170369679379636 -419.168908000586 483.727155433737 -0.866539956031073 0.386843385162356 RRAD other 1 1 1 3.16433245930588 -0.866539956031073 2.58850655287522e-05 174.900814145766 49.3456134126366 3.54440449819146 0.000452159091374805 -176.834109088267 132.932788874424 -1.33025200618724 0.184382513227474 FAM96B essential 0.237935522340291 1 1 3.54440449819146 -1.33025200618724 1.37870936224394e-22 921.980608677239 94.1681037303422 9.79079510103976 5.98360094918821e-20 -1298.59872829979 492.731601587304 -2.63550932011755 0.00881417880580395 BLCAP other 2.03359630930981e-18 1 8.88385232925973e-16 9.79079510103976 -2.63550932011755 0.444664046358919 14.8633210781223 31.6655858205912 0.46938405505377 0.639115803069404 -33.6649543375652 51.3139780645607 -0.656058165968143 0.512259615139295 SERPINB12 other 1 1 1 0.46938405505377 -0.656058165968143 0.0871910523212053 -12.5685388678476 6.04858050236952 -2.07793198138371 0.0385226323507696 -19.8021242332117 13.0036052273216 -1.52281800985514 0.128804310100392 CHRFAM7A other 1 1 1 -2.07793198138371 -1.52281800985514 0.131000098055358 -9.29879453017853 11.1536523511508 -0.833699512717832 0.405076109665554 -72.0155027803899 36.1687822440413 -1.99109558885561 0.0473257565733569 ATF7IP2 other 1 1 1 -0.833699512717832 -1.99109558885561 0.00509341752808062 271.228250239019 158.887129454657 1.70704984834169 0.0888076883363465 -4905.63016636685 2069.33839225807 -2.37062733901815 0.0183654005125304 MMP10 other 1 1 1 1.70704984834169 -2.37062733901815 0.118574077768236 2.34060734225464 8.1195872964524 0.288266787066542 0.773329152199171 -50.5488745063968 26.3458606135202 -1.91866476665621 0.0559162044663667 TVP23A other 1 1 1 0.288266787066542 -1.91866476665621 3.28656235063866e-13 163.816632938786 22.5208593155715 7.27399566079252 2.72226619368147e-12 -112.638762007814 53.165050668374 -2.11866180115989 0.0348917032773231 COG1 essential 4.37079927011436e-09 1 3.80001137975996e-08 7.27399566079252 -2.11866180115989 0.000576753377983317 -108.188964642768 49.3945136794664 -2.19030326616501 0.0292257970608821 -399.959504518067 103.344372172057 -3.87016241051017 0.000131908676709549 PLEKHA7 other 1 1 1 -2.19030326616501 -3.87016241051017 0.0100329294835947 22.8051517935593 9.64247444628343 2.36507256727543 0.0186265218284466 -29.6188317358933 25.0992023424962 -1.18007063856945 0.238854115207302 ZNF606 other 1 1 1 2.36507256727543 -1.18007063856945 0.0263103811021336 -1013.7080810503 3660.04175580699 -0.27696626122966 0.781986525071861 -19278.4589952641 7404.99204217892 -2.60344087953826 0.00966343630855751 B2M other 1 1 1 -0.27696626122966 -2.60344087953826 6.83197552550952e-10 229.011080135407 45.56542258134 5.02598389659602 8.35021009067818e-07 -239.239591418736 89.289740413314 -2.67936260438565 0.00775768371545245 ZNF592 other 8.31109822678234e-06 1 0.00999102637349645 5.02598389659602 -2.67936260438565 0.116352573182186 71.1533055489773 65.9992712110331 1.07809229167795 0.281804573436238 -160.566894453007 132.228010759978 -1.21431830918542 0.225521557898522 CASC4 other 1 1 1 1.07809229167795 -1.21431830918542 0.121063603530506 -51.4517792543482 32.3165018458951 -1.59212093869881 0.112347932355699 -120.114331793261 59.2254439017656 -2.02808664452543 0.0433820963429278 HTR3A other 1 1 1 -1.59212093869881 -2.02808664452543 0.0569043068890453 543.025287338022 229.872226974374 2.36229184571548 0.018760558351089 785.678069979939 420.762092145001 1.86727389336486 0.062777471694979 NNMT other 1 1 1 2.36229184571548 1.86727389336486 2.58009679364297e-15 476.262465486441 74.6264869909306 6.38194942158166 6.13219871505106e-10 -565.963488075105 205.155337985473 -2.75870710278657 0.00613690918418403 AP1G1 other 3.56414571073839e-11 1 8.20549510060983e-06 6.38194942158166 -2.75870710278657 0.00255706098427363 -173.212716106977 127.632976166652 -1.35711570245617 0.175706901402522 -1041.84528724908 310.61985298631 -3.35408467048304 0.000892561860605312 SLFN5 other 1 1 1 -1.35711570245617 -3.35408467048304 0.000497315660144732 2.40900602644614 5.44959733092447 0.442052115075717 0.658751028214392 -37.935502329223 11.0261205332171 -3.4405122105222 0.000657873897489756 CATSPER2 other 1 1 1 0.442052115075717 -3.4405122105222 0.26678164257713 6.66289051742847 12.4252233232113 0.536239095596912 0.592170588932589 -42.6525126584183 32.4036063465353 -1.31628906370105 0.189031003880225 ZNF667-AS1 other 1 1 1 0.536239095596912 -1.31628906370105 0.0457671784163536 34.270652429333 13.7328066020348 2.49553157067363 0.0130801399970234 30.7951733440405 42.981001430587 0.716483383798624 0.474215489405161 C16orf45 other 1 1 1 2.49553157067363 0.716483383798624 8.9233517301194e-10 69.889070615538 14.7593922041015 4.73522687445873 3.29661646800682e-06 -63.9129130290642 30.7109220050786 -2.08111345593907 0.0382208709682513 SAAL1 other 1.08142099617317e-05 1 0.0381781153159869 4.73522687445873 -2.08111345593907 0.0650990957175105 3.98534332947448 1.77805598805966 2.24140485802338 0.025696006444852 -0.680690007990251 6.51438770880511 -0.104490251182042 0.916846803512731 YPEL4 other 1 1 1 2.24140485802338 -0.104490251182042 3.96038544749962e-07 2223.75169275497 517.903701283095 4.2937551657686 2.3319534108877e-05 -1799.84014666262 1013.44939150544 -1.77595463744768 0.0766906031202313 PPIB other 0.0042170184244976 1 0.255022425014679 4.2937551657686 -1.77595463744768 0.0167182822519036 31.1080038864234 29.8305620106462 1.0428232587546 0.297817331985851 -124.865162113114 58.3733324227191 -2.13907887267571 0.033185791749254 FAM96A other 1 1 1 1.0428232587546 -2.13907887267571 0.000194034403647823 15.8603365855866 34.3053669962274 0.462328142046425 0.644162185011741 -464.099044179371 120.760858957169 -3.84312473583826 0.000146685292171618 FAM111A other 1 1 1 0.462328142046425 -3.84312473583826 0.014540604731136 22.8382151615843 39.7664826788773 0.574308151565922 0.566162775331208 -193.061883207841 77.8162379866647 -2.48099738824338 0.0136149900218732 PCLAF other 1 1 1 0.574308151565922 -2.48099738824338 0.00404209824386538 48.803672044062 16.2267919421844 3.00759831135742 0.00284194259721482 -18.7558633382097 33.6343209941181 -0.55764061184674 0.577479695810752 KIF7 other 1 1 1 3.00759831135742 -0.55764061184674 0.00393497705424347 37.002763474423 15.8407395528989 2.33592398579973 0.0201144131811024 -47.9985122301968 41.50156850206 -1.15654694419114 0.248322879036071 LDHD other 1 1 1 2.33592398579973 -1.15654694419114 0.703696745165848 -14.2716948569812 30.9244840871756 -0.461501469733481 0.644752416418242 -51.4501439290266 64.0991779565235 -0.802664645152292 0.422764322598732 PLIN1 other 1 1 1 -0.461501469733481 -0.802664645152292 0.00869942763886786 19.9435710577942 7.04652613817044 2.83026993255038 0.00494489463033358 -6.08682931433164 14.6057904032485 -0.416740836769631 0.677147386144506 PEX11A other 1 1 1 2.83026993255038 -0.416740836769631 7.5148775535579e-05 34.5199407542893 13.1102072402915 2.63305835839112 0.00887401350366604 -70.6655235027868 34.3477753700957 -2.05735372207862 0.0404647438070047 TMEM170A other 0.656725149405425 1 1 2.63305835839112 -2.05735372207862 0.80328606301615 -2.87705225264096 4.77139130841188 -0.602979732047707 0.546949273668444 0.899745174838365 9.88997131580074 0.0909755090392309 0.927568971406332 MESP1 other 1 1 1 -0.602979732047707 0.0909755090392309 0.428157528687478 74.3869641424598 57.5619634600235 1.2922937243814 0.197187855016068 23.6482704921904 119.312404014561 0.198204626648076 0.843010823415614 ANPEP other 1 1 1 1.2922937243814 0.198204626648076 0.171179127281334 -53.0593188949262 30.6912903607535 -1.72880704171291 0.0848111629808963 -111.55397260274 94.1808522055338 -1.18446552553264 0.237110580489654 SCNN1G other 1 1 1 -1.72880704171291 -1.18446552553264 0.602445419993705 3.6568064590082 3.78441324021615 0.966280960056923 0.334633304463404 4.52786650214735 7.41125868147956 0.610944334389826 0.541670140310076 RBPMS2 other 1 1 1 0.966280960056923 0.610944334389826 1.24563367802737e-06 227.023588090699 110.888941738583 2.04730593088263 0.0414443278013044 -810.751051926065 235.283027512439 -3.44585438438904 0.000645218665839469 NAV2 other 0.0128125880121895 1 1 2.04730593088263 -3.44585438438904 0.053167238790954 7.63219125335714 7.41362862146727 1.02948119511368 0.304031101878309 -24.588672941516 14.5185834618252 -1.69359999935041 0.0913144169997211 ANKDD1A other 1 1 1 1.02948119511368 -1.69359999935041 1.00904474967653e-12 65.8083193359382 14.4157724024307 4.56502208128939 7.13928097206261e-06 -49.2854698953058 22.4161302386035 -2.19866093615167 0.0286197258906061 C18orf54 other 1.32961826664876e-08 1 0.0809808640661062 4.56502208128939 -2.19866093615167 1.01374809581582e-09 243.891103404345 56.1455535753253 4.34390771616739 1.88656172316276e-05 -665.71318867982 179.077627307561 -3.71745593622633 0.000237866947334328 DCTN5 essential 1.22470907455509e-05 1 0.207691580102988 4.34390771616739 -3.71745593622633 0.198123571393558 79.8797225564438 71.0903350720892 1.12363688362759 0.26201730219159 -241.710506759149 226.744376331238 -1.06600441726523 0.287232868689083 PLK1 essential 1 1 1 1.12363688362759 -1.06600441726523 2.20203029581686e-06 172.21573297408 45.9985346281372 3.74393954864675 0.000214748876566325 -184.749651491684 90.0818746418529 -2.0509081568985 0.0410899183659758 CLPX other 0.0221744450788758 1 1 3.74393954864675 -2.0509081568985 0.000902575556456818 44.2297004306317 12.9857388024368 3.40602110542465 0.000743229616147465 -40.3578693824503 41.7605866753633 -0.966410498400863 0.334568607435264 ZBTB39 other 1 1 1 3.40602110542465 -0.966410498400863 0.730912547389735 17.9192413067713 26.1646940172292 0.684863400083014 0.493930562834069 -17.3680773525324 84.833552288477 -0.204731228199335 0.837913509352443 CHP2 other 1 1 1 0.684863400083014 -0.204731228199335 0.00551824897648873 146.843372944956 52.5305351194739 2.79539076864493 0.00549676029747329 -190.631391282495 173.305086176909 -1.09997574501593 0.27216948977426 NEMP1 other 1 1 1 2.79539076864493 -1.09997574501593 1.44755664131682e-10 264.29096698891 43.8274834253371 6.03025650421263 4.51303128533145e-09 -332.84341084362 144.592583621508 -2.30193971576637 0.0219803738500557 NAB2 other 1.80104997312638e-06 1 5.89627537428555e-05 6.03025650421263 -2.30193971576637 1.72010110403813e-07 133.333601065705 46.7430282282409 2.85248102486327 0.00462021789687583 -318.300180229596 93.4719557827177 -3.40530138226172 0.000745122031308078 VPS39 other 0.00187284608207672 1 1 2.85248102486327 -3.40530138226172 5.74759614121078e-14 1163.39640874069 154.113370359024 7.54896480448408 4.61138550396163e-13 -865.399123006878 508.440107650517 -1.70206698878626 0.0897140100994134 STAT6 other 7.75868003102043e-10 1 6.49605875943075e-09 7.54896480448408 -1.70206698878626 5.82139322690499e-10 213.164589017217 55.612232958796 3.83305214834934 0.000152460359915935 -827.215571856486 197.68880837887 -4.1844329916296 3.70026399657825e-05 PATL1 other 7.1029130584826e-06 0.536242258384119 1 3.83305214834934 -4.1844329916296 0.000738702732738206 23.5050509760254 6.43330184535269 3.65365274956049 0.000302007861908111 -10.0490103981675 21.0783764730533 -0.476744990821007 0.633869109051558 ATP23 other 1 1 1 3.65365274956049 -0.476744990821007 0.229082841475332 9.38501362255327 11.826705120439 0.793544231210604 0.428048824038529 -39.6995377221836 30.5686250179955 -1.29870210710533 0.19498124925941 ELFN2 other 1 1 1 0.793544231210604 -1.29870210710533 2.31705579143956e-14 180.229812186154 26.2089846129029 6.87664229835997 3.23892672829045e-11 -231.300886086267 93.1669645558696 -2.48264915776624 0.013554860908445 STX3 other 3.1511958763578e-10 1 4.44024465181337e-07 6.87664229835997 -2.48264915776624 6.13991575776125e-09 79.9894068304546 21.4130635437952 3.73554240227494 0.000221845340825529 -289.261108443505 76.1185586424894 -3.80013906729494 0.000173188246875663 MRPL16 essential 7.19782324282352e-05 1 1 3.73554240227494 -3.80013906729494 1.99062450015352e-15 458.62345349715 60.4995101611617 7.58061432688372 3.7509621853376e-13 -542.177480130025 198.223475637706 -2.73518299679583 0.00658216210163861 PIP4K2C other 2.75562149556252e-11 1 5.29298273972988e-09 7.58061432688372 -2.73518299679583 0.00036018736859302 47.6181007676611 31.8402053930647 1.49553371844872 0.135770053564205 -195.426610630649 67.6893151283957 -2.88711165506632 0.00415507811775901 MTMR10 other 1 1 1 1.49553371844872 -2.88711165506632 2.5493007849286e-27 1457.08353093238 144.013888096151 10.1176598326375 4.72160739894025e-21 -2631.51095279939 643.555748456575 -4.08901786536828 5.48918574703526e-05 YWHAB other 3.82853991880578e-23 0.7907720987179 7.04133311403959e-17 10.1176598326375 -4.08901786536828 0.259348843326303 23.7656887686142 14.4405815857987 1.64575703737488 0.100801759312224 18.1444950676473 31.1787006920461 0.581951610070653 0.561011603458802 SCG5 other 1 1 1 1.64575703737488 0.581951610070653 0.394614180696476 198.810188073805 167.306772695545 1.18829731080634 0.235602991255533 387.88898297531 361.232527833685 1.07379306426662 0.28372956206082 GREM1 other 1 1 1 1.18829731080634 1.07379306426662 1.5468968550211e-09 24.5625833555976 3.79460373626267 6.47302987684016 3.60793617255983e-10 4.56471206691596 16.2722165748679 0.280521835849092 0.779258445072681 NYAP1 other 1.85488401885581e-05 1 4.85014859677218e-06 6.47302987684016 0.280521835849092 5.77338335627248e-17 271.000037682296 31.1962057644172 8.68695506526636 1.95071683749215e-16 -134.030351761567 135.029009335575 -0.992604125743631 0.321652875221724 TSC22D4 other 8.13238779564542e-13 1 2.84015496887605e-12 8.68695506526636 -0.992604125743631 0.703177758754712 -15.5268567817978 18.8563229850643 -0.823429721377618 0.410876908760904 -6.87448942618085 62.8274723591795 -0.109418526132644 0.912939123500431 MS4A7 other 1 1 1 -0.823429721377618 -0.109418526132644 0.678962494679253 -1.48946361300601 2.12856115412131 -0.699751383756164 0.48459094435686 -5.18640061927661 7.09216304691571 -0.731286151343082 0.465139532161788 MS4A14 other 1 1 1 -0.699751383756164 -0.731286151343082 0.022433416473939 44.5588314817196 30.9437234601825 1.43999578909941 0.150846176146426 -102.874750579652 60.6455236334629 -1.69632883708647 0.0907961203619256 DIS3L other 1 1 1 1.43999578909941 -1.69632883708647 0.0176911942252633 28.8634969011686 37.7032127050708 0.765544759459892 0.444511488808276 -170.782080989131 76.3375030483588 -2.23719763116882 0.0259616470282028 CCNDBP1 other 1 1 1 0.765544759459892 -2.23719763116882 0.227550243018958 0.889140422754726 1.73467841570389 0.512567871200459 0.608607244724013 -4.62274931557576 3.51219456767693 -1.31619966562199 0.189049050570135 EPB42 other 1 1 1 0.512567871200459 -1.31619966562199 2.17441182301047e-05 589.389872652151 205.76921977035 2.86432476786345 0.00445513207951982 -989.207029802939 400.841879193153 -2.46782355125691 0.0141164583442322 SMAD3 ts 0.201263558337849 1 1 2.86432476786345 -2.46782355125691 0.644228705830016 -12.0427967001162 13.8527601331933 -0.869342758000972 0.385311264517643 -34.3153649028014 61.4991013445166 -0.557981566438956 0.577247126161801 MS4A8 other 1 1 1 -0.869342758000972 -0.557981566438956 0.0466967681392434 126.718495614246 53.5368947447828 2.36693772058184 0.0185308184627423 23.7907845997533 108.39587856209 0.219480527445753 0.826415680464747 MAP1A other 1 1 1 2.36693772058184 0.219480527445753 0.00392727155869795 44.8620042772918 20.4781310725167 2.19072747012057 0.0291925026868324 -75.8320592558787 42.3597156164257 -1.79019283185352 0.0743682063387112 RCCD1 other 1 1 1 2.19072747012057 -1.79019283185352 7.16791802782323e-08 54.7146948909817 16.1749688572211 3.38267698528242 0.000807533615213925 -116.544216046762 42.800226255456 -2.72298130741553 0.00682668376549139 AKTIP other 0.000796284013710883 1 1 3.38267698528242 -2.72298130741553 3.54081791025114e-12 194.760475243929 34.8118802398849 5.59465544239082 4.79359890214541e-08 -74.8361371126357 62.6469748935814 -1.19456904726461 0.233151298115845 MAPRE2 other 4.60731226481878e-08 1 0.000604520757549557 5.59465544239082 -1.19456904726461 0.0185595742091064 16.0103165932717 44.9022145157887 0.356559621077087 0.721660985311486 -186.896034418678 73.567700974042 -2.54046316446158 0.011551925097748 EVA1C other 1 1 1 0.356559621077087 -2.54046316446158 2.38891850813559e-12 414.880759976484 61.3419362288426 6.76341154978752 6.41457895432072e-11 -443.352071816162 202.375047583648 -2.19074474402735 0.0291912398812703 MBD6 other 3.11908012253564e-08 1 8.74435403053e-07 6.76341154978752 -2.19074474402735 2.61038220569533e-06 46.6253976788995 9.61169276709687 4.85090387392629 1.92500679017085e-06 -28.838483155058 41.5818130894014 -0.693535971917697 0.488477930281218 CNPY4 other 0.0261560297010672 1 0.0225784046419139 4.85090387392629 -0.693535971917697 4.96632338920949e-10 1686.05322141826 373.228105977081 4.51748728034377 8.82312288030634e-06 -2179.94003957729 755.14901982483 -2.88676801842763 0.00415779697593481 PDIA3 other 6.0782831960535e-06 1 0.0994895335983343 4.51748728034377 -2.88676801842763 4.11479552804566e-11 451.419267302292 80.4808638304379 5.60902611897122 4.4147442588189e-08 -306.418812857042 212.324313007468 -1.44316403767789 0.149955505993173 NUDT21 essential 5.21430711689923e-07 1 0.000557317315233298 5.60902611897122 -1.44316403767789 0.00494247973752116 -17.1324184043753 28.3427539277011 -0.604472608698435 0.545957812882563 -151.421849581441 52.4043838174651 -2.88948821741467 0.00412207691288227 NKX3-1 other 1 1 1 -0.604472608698435 -2.88948821741467 0.744333027640777 -4.0135809771678 5.33404918225063 -0.752445438734092 0.45233983948236 -0.106621486876988 15.7309776939892 -0.00677780421224091 0.994596385985634 SGSM1 other 1 1 1 -0.752445438734092 -0.00677780421224091 1.37148211809559e-06 36.9251697841063 7.2246443317166 5.11100174468142 5.55036742554838e-07 -3.73289100980483 20.1588864737855 -0.185173472486145 0.853211393655824 DUSP18 other 0.0140645491210703 1 0.00669707333566668 5.11100174468142 -0.185173472486145 0.104194131332881 19.4312473905615 48.3163110349847 0.402167445616695 0.687830977898022 -246.091322972741 126.241896407813 -1.9493633252923 0.0521308938146329 TEF other 1 1 1 0.402167445616695 -1.9493633252923 0.00555091777505382 -119.086513388827 44.0907372359998 -2.70094175906847 0.00728367006545378 -272.522933172869 114.774555639728 -2.37441941424984 0.0181679017446895 MEI1 other 1 1 1 -2.70094175906847 -2.37441941424984 0.266041897107617 56.1383244821906 36.7896045747142 1.52592899899704 0.128021485891373 -42.0550036940878 87.7471264191333 -0.479274996348117 0.632072428101187 B4GALNT2 other 1 1 1 1.52592899899704 -0.479274996348117 0.000101577746519748 69.6253010153025 20.2379734083808 3.44032970151399 0.000658301703857506 -88.676291351767 39.6747070721228 -2.23508370687064 0.0261037477345502 PBX3 other 0.874381242041988 1 1 3.44032970151399 -2.23508370687064 0.050827946416679 -6.00564651169255 2.69143682109502 -2.23139048430241 0.0263519919223521 -7.40990131342774 6.41936355989141 -1.1543046665444 0.249242011955363 GNGT2 other 1 1 1 -2.23139048430241 -1.1543046665444 0.000285042921574819 440.076806918479 109.522317406725 4.01814732685212 7.32743102114408e-05 -137.866875612303 261.22239535593 -0.52777586479311 0.598022968419503 PHB essential 1 1 0.770625920493723 4.01814732685212 -0.52777586479311 0.000719417706829296 214.755073119532 61.1341916113932 3.51284718843832 0.000527037671885086 -10.679818584476 142.664592462432 -0.0748596298502612 0.940386989634284 SNRPD1 essential 1 1 1 3.51284718843832 -0.0748596298502612 7.74911778941053e-05 94.3758799010709 21.6030250088737 4.36864188521306 1.69278666328896e-05 47.3905518370549 51.5278340183828 0.919707818887712 0.358420395912996 SAMD14 other 0.675645580058704 1 0.187019070560165 4.36864188521306 0.919707818887712 1.37850355366263e-05 31.1717265285894 6.59711988223834 4.72505079262151 3.45047500166384e-06 -4.50237255833912 12.9170661610957 -0.348559998237029 0.727648873957932 PIP5KL1 other 0.130020455181459 1 0.0399081938692439 4.72505079262151 -0.348559998237029 0.491422114800699 -1.46221830194227 9.93669200395716 -0.147153429064719 0.883103876838099 -28.2312434782108 23.7011351910845 -1.19113465454728 0.234486240698808 TMEM92 other 1 1 1 -0.147153429064719 -1.19113465454728 0.00580661860459604 450.926258758961 140.45551702051 3.21045601001998 0.00146020117183989 -4.92537900247007 274.524363869626 -0.0179415004666368 0.985696737985063 FAM102A other 1 1 1 3.21045601001998 -0.0179415004666368 0.356270689806512 24.5889759421644 23.3360113094713 1.05369232196869 0.292821244297697 -50.7673184132093 55.6613769095588 -0.912074426324351 0.362418283391369 ACSF2 other 1 1 1 1.05369232196869 -0.912074426324351 7.23581742978437e-14 534.769071976912 67.9140859442967 7.87419965300764 5.37598852159646e-14 -162.583007730797 132.251801133617 -1.22934437442206 0.219845873717195 GOLGA2 other 9.75315831360636e-10 1 7.67583641113543e-10 7.87419965300764 -1.22934437442206 4.32097383765003e-16 255.764762279404 32.4815378580336 7.87415803393513 5.37748752854191e-14 -203.310577271341 63.2525907635435 -3.21426482009843 0.00144114361420252 TRUB2 other 6.03207947735944e-12 1 7.67743894449929e-10 7.87415803393513 -3.21426482009843 1.05335114067871e-07 163.854748877692 43.8296731861761 3.73844331856372 0.000219295233303958 -340.887489795419 85.3512661088297 -3.99393594654777 8.06720452537133e-05 COQ4 essential 0.00116100362725607 1 1 3.73844331856372 -3.99393594654777 2.92076047408247e-06 410.934686010723 84.4139977053541 4.86808701378041 1.77319747219012e-06 -182.921412911477 164.38273566074 -1.11277751995196 0.266639218762426 SLC27A4 other 0.0291521102918171 1 0.0208421630881227 4.86808701378041 -1.11277751995196 1.6801822515354e-16 293.718322411207 46.7306452457377 6.28534703226674 1.06986352639353e-09 -520.515247760188 91.00044439903 -5.71991984432261 2.4474200244091e-08 URM1 essential 2.3561195713281e-12 0.000371200195102127 1.42291849010339e-05 6.28534703226674 -5.71991984432261 1.52907228288185e-09 711.991573864199 123.038538688595 5.78673626534379 1.71042433384199e-08 916.250763772545 240.337302332824 3.81235353346732 0.000165111556794431 CERCAM other 1.83427511054507e-05 1 0.000219481650518605 5.78673626534379 3.81235353346732 1.46715709128551e-18 176.976333459675 20.8849043633707 8.47388766453093 8.79323431186141e-16 -148.147928047598 40.8133322615893 -3.62989052445061 0.00032999451889938 DOLPP1 other 2.10243611181213e-14 1 1.27413965178872e-11 8.47388766453093 -3.62989052445061 0.0555127122630376 7.24329668754134 6.4376781503417 1.12514116400132 0.261375058063343 -31.8080132272634 15.6336233784542 -2.03458996403228 0.0427188580060848 CCDC103 other 1 1 1 1.12514116400132 -2.03458996403228 0.000101807471585052 104.721291259326 29.075494668036 3.60170282414665 0.000366353287357153 -112.578300810546 56.7946110786823 -1.98220040022075 0.0483119427184952 ENDOG other 0.876155100460955 1 1 3.60170282414665 -1.98220040022075 4.34926077815692e-06 97.943520709073 22.9167526495967 4.27388304995284 2.53755595190714e-05 143.249825064143 44.8706731810777 3.19250447805968 0.00155058356113461 PRRX2 other 0.0428315201432893 1 0.276872729912588 4.27388304995284 3.19250447805968 0.0825360037206774 701.207146933859 352.609410601298 1.98862289505576 0.0475969643637506 1103.31445285959 606.419090075255 1.81939267895189 0.0697888352227042 UGT1A6 other 1 1 1 1.98862289505576 1.81939267895189 2.53966684502394e-05 165.692029155339 50.7475116938373 3.26502765603502 0.00121305322680471 -181.207597028218 98.4553537528945 -1.84050526579811 0.0666198751352559 C15orf39 other 0.233598556405302 1 1 3.26502765603502 -1.84050526579811 0.916058173475379 0.48564909410147 6.46478365743484 0.0751222499987217 0.940164385244678 -4.46830461421094 12.6921611892977 -0.352052305952331 0.725030764272061 ISLR2 other 1 1 1 0.0751222499987217 -0.352052305952331 0.000151706533399219 62.9993405333561 19.4171889739179 3.24451395194124 0.00130126409639874 -114.270802367992 46.1907726900926 -2.47388808874595 0.0138852463116836 SP2 other 1 1 1 3.24451395194124 -2.47388808874595 0.475879851094693 -3.00030831474706 16.5250706171319 -0.181560998089568 0.856042568341831 -47.8539563207622 39.3108282351775 -1.21732251568131 0.224381284360884 PRR15L other 1 1 1 -0.181560998089568 -1.21732251568131 0.00907077280585942 21.8007010563943 13.2318663447326 1.6475907848837 0.100418199789558 -83.1930030954986 40.6377940907437 -2.04718304614984 0.0414564637000323 COQ7 other 1 1 1 1.6475907848837 -2.04718304614984 0.38847563846909 78.130004380116 57.2450694317837 1.36483377792423 0.173264171285609 97.7776397041859 174.444751073318 0.560507777405643 0.575525346606189 GPRC5B other 1 1 1 1.36483377792423 0.560507777405643 4.88779398110133e-15 383.119539716232 45.4037974299268 8.43805059053735 1.16401124974744e-15 -94.2719109596687 86.7233299879252 -1.08704210242843 0.277844051857105 CRK other 6.72364940040299e-11 1 1.68583749300922e-11 8.43805059053735 -1.08704210242843 1.94876854164899e-05 75.5069298438752 24.5658243965344 3.07365747735815 0.00229642578995928 -105.959740564375 47.7700799270599 -2.21811939034149 0.0272484382336096 FBXO22 other 0.181060085204608 1 1 3.07365747735815 -2.21811939034149 0.000574405716859704 177.4999508185 57.3330164491576 3.095946486191 0.00213530339928396 -117.548328355294 111.231905325277 -1.05678607240922 0.29140637427465 TBC1D2B other 1 1 1 3.095946486191 -1.05678607240922 5.38827600725261e-05 82.1332829226189 42.6409028922055 1.92616190914739 0.0549895757455173 -306.717289372521 112.987189845039 -2.71462003606941 0.00700320045630799 NOD2 other 0.478909971524612 1 1 1.92616190914739 -2.71462003606941 3.74152148353954e-08 -40.0737565496369 13.5685111342245 -2.95343801196852 0.00338058183480923 117.577873702801 35.9529897223961 3.2703225687392 0.00119399836867697 SNX20 other 0.000422193284202602 1 1 -2.95343801196852 3.2703225687392 5.92087129100645e-06 14.9829049153213 7.16885697739731 2.08999913969004 0.037422087050426 -28.365649481542 11.5699248703153 -2.45167101770203 0.0147638892063453 KATNAL2 other 0.0576811281169848 1 1 2.08999913969004 -2.45167101770203 4.446110655681e-17 75.4419223678994 19.9637269442231 3.77894982127723 0.000188426600823805 -148.002570754195 32.2197557580525 -4.59353484444727 6.31749144478618e-06 HDHD2 other 6.27301752410033e-13 0.0934609684341668 1 3.77894982127723 -4.59353484444727 0.0184791190227753 40.3503113874778 16.8765993561237 2.39090296190722 0.0174014058188558 -25.9109439426424 39.4534189190747 -0.656747745887116 0.511828798727253 ZNF91 other 1 1 1 2.39090296190722 -0.656747745887116 0.0280225898583726 2195.73961195103 995.07766117736 2.20660125095469 0.0280517921386772 4588.60788653008 1818.49916677315 2.52329391751791 0.0121101477802035 IGF2 other 1 1 1 2.20660125095469 2.52329391751791 1.82790704878457e-27 126.34807528257 16.6464885737126 7.59007370972482 3.52604818381388e-13 -77.5140313059069 30.7562259352495 -2.52027122798147 0.0122125574980565 RNF214 other 2.74697871291345e-23 1 4.97701701145329e-09 7.59007370972482 -2.52027122798147 5.18801665261835e-05 253.694913605347 58.3856062556128 4.34516193074484 1.88158341234797e-05 -143.372177991588 146.231461753243 -0.980446863298953 0.327620389183527 CDK12 other 0.462252283748295 1 0.207218781201882 4.34516193074484 -0.980446863298953 0.749854988738811 -1.33266863941258 3.49213082663933 -0.381620479177489 0.702996960203253 4.14388872750229 9.3481434406997 0.443284675057588 0.657860318255733 DPEP2 other 1 1 1 -0.381620479177489 0.443284675057588 1.39672671500721e-08 86.8404685353595 20.7359598330147 4.18791650999906 3.6468627472804e-05 -136.017488014994 55.5084378342591 -2.45039300909754 0.0148067849419677 DUS2 other 0.000160944819370281 1 0.393605896313974 4.18791650999906 -2.45039300909754 0.202863415587116 47.5522515110147 26.5994845950163 1.78771326719331 0.0747714124035013 10.7388761725333 72.9099920888911 0.147289498529098 0.882996567058377 POP5 essential 1 1 1 1.78771326719331 0.147289498529098 0.0388280873751661 72.2366056797668 29.5233468315672 2.44676208601558 0.0149539296814486 -18.1273648360135 69.6053396517383 -0.260430664180529 0.794699617101629 ENGASE other 1 1 1 2.44676208601558 -0.260430664180529 7.75087727177378e-12 299.581306397208 96.958010372897 3.08980459938306 0.00217919327051549 -601.289975599008 183.328451207893 -3.27985084495778 0.00115343091227671 ATP5L other 9.99630641740664e-08 1 1 3.08980459938306 -3.27985084495778 4.31132212344102e-05 -55.2756705644072 20.0909110477953 -2.75127745242159 0.00627557182597062 40.3060968226874 37.9879454166012 1.06102334255417 0.289481931051232 CD3D other 0.387501632454879 1 1 -2.75127745242159 1.06102334255417 9.34314714668943e-09 280.19336996819 47.7514247679214 5.8677488960794 1.10307151433635e-08 -85.8100098404923 110.084903588046 -0.77948934907193 0.436267611768119 TBC1D16 other 0.000108623428727411 1 0.000142351378925106 5.8677488960794 -0.77948934907193 0.000522788353080323 60.7767242927131 16.2071497133003 3.74999462384414 0.000210173931080055 -11.1115642943252 37.1902555267172 -0.298776228798502 0.765306553719769 TEPSIN other 1 1 1 3.74999462384414 -0.298776228798502 1.00759614123384e-10 428.587601534472 143.043030164708 2.99621450301334 0.00294853635688668 -681.955081284697 220.278304731098 -3.09587946991505 0.00213688853963605 MYO5B other 1.26020049384116e-06 1 1 2.99621450301334 -3.09587946991505 0.0408301100740694 93.6593190791522 40.6470857700412 2.30420748018751 0.0218552101731408 36.7649920414537 63.9313657804789 0.575069710972446 0.56565079716704 ACAA2 other 1 1 1 2.30420748018751 0.575069710972446 6.41999485409615e-10 262.422294197276 146.472750790624 1.79161170102141 0.0741399716397328 -1369.43949401437 291.079284327378 -4.70469582601472 3.78848193296523e-06 RRM1 essential 7.81826973331829e-06 0.0563082069696623 1 1.79161170102141 -4.70469582601472 6.41718415538345e-06 26.4583855200236 12.0524601246272 2.19526845527248 0.0288621563362584 -66.7267213474738 23.9634657748772 -2.78451881603156 0.00567986192450463 TRIM68 other 0.0622980237804626 1 1 2.19526845527248 -2.78451881603156 0.390966550206085 17.1015210495622 12.4959235065427 1.36856800064502 0.172118962310701 5.57877405681177 27.6814496428996 0.201534750845058 0.840411790338607 FN3K other 1 1 1 1.36856800064502 0.201534750845058 0.97333425977005 -0.104386170823333 3.25212880088035 -0.0320977972321011 0.974414259878443 2.50260916267143 11.7758954806342 0.212519648020573 0.831838241162557 PRRT2 other 1 1 1 -0.0320977972321011 0.212519648020573 1.68838563515302e-06 26.3544475123167 5.98418410263065 4.40401683175678 1.45087350135018e-05 -14.1579296002955 16.4510934608471 -0.86060720729542 0.390098751886773 ZNF23 other 0.0171675051382359 1 0.160945397504775 4.40401683175678 -0.86060720729542 0.00051462502716024 72.4216304122965 29.3280768697103 2.46936172235326 0.0140603783389577 -171.12929746462 72.9721965232992 -2.3451301402169 0.0196349131316574 IRGQ other 1 1 1 2.46936172235326 -2.3451301402169 5.37756050852353e-41 92.9644061277322 5.97452218119323 15.5601407624476 5.13954342883416e-41 -10.3835918848119 25.2025604972624 -0.412005434366078 0.680612152107563 ZNF226 other 8.21798796912565e-37 1 7.86093167440184e-37 15.5601407624476 -0.412005434366078 1.59785929589791e-10 32.1971981661448 5.30900242211174 6.06464183027023 3.74936903048029e-09 -53.7129867774315 22.0345086519593 -2.43767572156212 0.0153295726632538 ZNF180 other 1.98677824851946e-06 1 4.91167342992919e-05 6.06464183027023 -2.43767572156212 8.87376831239419e-05 50.0411107124437 13.5743635086174 3.68644251206889 0.000268249223329853 -57.1897831498217 46.6653802048845 -1.225529137419 0.221303182573886 ZNF668 other 0.768468335853337 1 1 3.68644251206889 -1.225529137419 6.96063847032673e-06 76.8484403381699 23.7364406381654 3.23757220004615 0.0013356543607391 -219.404766443163 81.6001447425126 -2.68877913311907 0.00755799332165887 ZNF646 other 0.0673998623081737 1 1 3.23757220004615 -2.68877913311907 0.0177070106256605 168.822029242258 61.5166103824627 2.74433243627457 0.00641566048908422 3.07059403942289 211.479235147266 0.014519600646771 0.988424751752274 VKORC1 other 1 1 1 2.74433243627457 0.014519600646771 0.611319739060165 65.3671001515482 116.297814068788 0.562066455633332 0.574467943772987 -198.993373795897 274.130994927728 -0.725906145156476 0.468431898818416 LPO other 1 1 1 0.562066455633332 -0.725906145156476 2.34530916905865e-05 60.6136642276104 14.0817425009008 4.30441504123037 2.23414443374098e-05 -40.8099555326353 33.089982164183 -1.23330243365342 0.218376669247378 SMG8 other 0.216472036304113 1 0.244772864160662 4.30441504123037 -1.23330243365342 9.33848134258974e-08 3033.58750487212 590.131105228578 5.14053144800275 4.786489173578e-07 -1933.19437971494 1485.40433310883 -1.30146003793387 0.194040160767135 TPM4 other 0.00103292942130385 1 0.00579021595327731 5.14053144800275 -1.30146003793387 1.78152354747253e-11 282.156689365328 52.8573747059503 5.3380761139763 1.78683870004196e-07 -440.283135111196 129.519455750297 -3.39935905814819 0.000761197102093619 RAB8A other 2.27749970308889e-07 1 0.0022019213300617 5.3380761139763 -3.39935905814819 2.50858564842538e-06 791.952335858576 336.231249399071 2.35537992757661 0.0191108003791769 -1527.89427933179 551.745693962109 -2.76920018778926 0.00594932687706048 GPX4 other 0.0251661312250035 1 1 2.35537992757661 -2.76920018778926 2.04014048740029e-08 444.376197028635 142.528524255346 3.11780536106946 0.00198853137754455 -683.066507307862 234.775680828605 -2.90944319657421 0.00387589711078414 MIDN other 0.000233494078782963 1 1 3.11780536106946 -2.90944319657421 0.130230914084236 -4.98681850289467 3.68175250602438 -1.35446869248675 0.176545474163255 -15.7768667084856 8.59095313118784 -1.83645126071176 0.0672213265622879 FAM129C other 1 1 1 -1.35446869248675 -1.83645126071176 2.2131678566986e-08 59.3813702379351 12.5100141098554 4.74670689549058 3.12280734562504e-06 -68.3925758811358 29.6282882925032 -2.3083539354665 0.0216166337601078 KLHL26 other 0.000252765900913548 1 0.0362058283651768 4.74670689549058 -2.3083539354665 1.80690393315552e-12 463.684017397654 71.9146180735134 6.4477018695095 4.21541902729566e-10 -331.683290504662 163.578695703649 -2.02766802289195 0.0434277044925036 GATAD2A other 2.3655986292872e-08 1 5.66004312794988e-06 6.4477018695095 -2.02766802289195 0.00196036490371466 148.436814410647 102.905248783916 1.44246106165429 0.150150393872387 -587.701789517383 261.82536395271 -2.24463276072646 0.025474644523759 MVD essential 1 1 1 1.44246106165429 -2.24463276072646 0.859579452035653 -23.7431375609431 53.8005990134311 -0.441317345835048 0.65928130724734 12.4927364177323 136.8867145654 0.091263322795023 0.927340462156116 CDT1 essential 1 1 1 -0.441317345835048 0.091263322795023 0.00048234799768003 44.2495157569655 39.2958835520338 1.12605982502906 0.260983979854884 -286.051781688038 99.9818681208285 -2.8610365765755 0.00450041805090985 TRAPPC2L other 1 1 1 1.12605982502906 -2.8610365765755 1.45677587174212e-06 202.655881072232 91.332365544364 2.21888352353901 0.0271958550471902 -777.79302893549 234.018704980792 -3.32363615549163 0.000991559758282179 ANKRD11 essential 0.0148999036161784 1 1 2.21888352353901 -3.32363615549163 0.000686106382063008 16.0558106268601 7.30522615210553 2.19785264583937 0.0286778616091354 -34.8955372892341 18.653634639728 -1.87070980874229 0.0623007413353197 SPATA33 other 1 1 1 2.19785264583937 -1.87070980874229 1.11047548208815e-05 11.8136846485233 2.46639930758746 4.78985078052063 2.58048745851854e-06 11.4730864583021 7.83734900892815 1.46389888280236 0.144225138865613 PROCA1 other 0.105495170798374 1 0.0300755813290336 4.78985078052063 1.46389888280236 0.0230897858695552 1413.36406159675 952.820185534031 1.48334815220628 0.138966151760829 -3488.74239215032 2441.38805087581 -1.42899953610357 0.153979782784402 RPL13 essential 1 1 1 1.48334815220628 -1.42899953610357 0.246724979031332 0.487450252600654 26.7615278434712 0.0182145898190777 0.985479086383959 -111.883795536691 68.1326210528749 -1.64214723883678 0.101547978748582 ZNF641 other 1 1 1 0.0182145898190777 -1.64214723883678 0.0103806534445889 53.5332282637247 22.3561370739304 2.39456521878952 0.0172186851887522 -76.4594102416378 56.4304841114836 -1.35493096409709 0.176401295360155 CACNB3 other 1 1 1 2.39456521878952 -1.35493096409709 7.09846307679589e-05 102.030308986884 24.4725003963579 4.16918203429956 3.95528776898576e-05 -75.3919675120451 77.4135594901551 -0.973885815464059 0.330860502598084 DHRS13 other 0.622109304050392 1 0.425707622575937 4.16918203429956 -0.973885815464059 2.59619016938515e-07 258.686653568284 45.8519933065254 5.64177552410723 3.74127987635518e-08 90.1909406687382 110.692480772859 0.814788322016289 0.415807116065913 TP53I13 other 0.00280025071669882 1 0.000473646032346566 5.64177552410723 0.814788322016289 0.000606237195493212 333.885108294245 119.881344695891 2.78512982266948 0.00567145928364899 -632.015981856692 311.39289178613 -2.02964164734618 0.0432253336694182 KMT2D other 1 1 1 2.78512982266948 -2.02964164734618 0.117944015668628 77.7315916221879 52.49604208447 1.48071337448854 0.139679316173502 210.430776513692 126.732050452852 1.66043850597982 0.0978181645114147 CORO6 other 1 1 1 1.48071337448854 1.66043850597982 0.483185510305001 -5.03763848687496 5.50143840286255 -0.915694790703054 0.360520853061839 -13.8915183373812 14.2900366824911 -0.972112153805866 0.331733595111283 RHEBL1 other 1 1 1 -0.915694790703054 -0.972112153805866 0.149724365955089 523.81337571438 268.475832638234 1.95106341813719 0.0519246658226079 208.735750444146 688.604320308865 0.30312872616094 0.76198934986459 TUBA1A other 1 1 1 1.95106341813719 0.30312872616094 0.0871438325982741 1329.98313527576 789.892305319953 1.68375248919159 0.0932108183128521 -2209.787186843 2091.40760219453 -1.05660282793476 0.291494910453362 TUBA1C essential 1 1 1 1.68375248919159 -1.05660282793476 0.983279143016996 -0.381950260936779 2.2598533756223 -0.169015505632794 0.865892240748025 -0.621319502609363 5.78172657996317 -0.10746262280243 0.914489956671781 ZNF610 other 1 1 1 -0.169015505632794 -0.10746262280243 0.51640686063465 0.352327892137831 13.3174564784492 0.0264560948787767 0.978910199173024 38.8939882177274 34.2968402913052 1.13403998407362 0.257634631260444 ZNF528 other 1 1 1 0.0264560948787767 1.13403998407362 0.930055551045022 0.776331939421439 4.48595745341644 0.173058248430376 0.862715741440955 5.28927158679933 14.3764942267387 0.36791108481523 0.713184297239801 ZNF701 other 1 1 1 0.173058248430376 0.36791108481523 3.5244052009846e-10 108.798353371668 24.5996839589991 4.42275411151643 1.33718340544342e-05 -278.206534239415 72.1551494451602 -3.85567123592279 0.000139519933385092 SERTAD3 other 4.33537083773115e-06 1 0.148748282021526 4.42275411151643 -3.85567123592279 2.21367313491877e-07 159.030203049174 32.0359882272703 4.96411104664474 1.12582767272575e-06 -142.227464566063 86.0758495515126 -1.65235040150195 0.099447019832614 NCKAP5L other 0.00239630116854957 1 0.0133883426840546 4.96411104664474 -1.65235040150195 2.16075180719961e-10 175.244274162991 35.1737637432642 4.98224402262185 1.03067681145064e-06 -332.407355043547 102.36074021068 -3.24741062207427 0.00128811590819656 RAB4B other 2.67954831610823e-06 1 0.0122784528548115 4.98224402262185 -3.24741062207427 0.291786410414635 56.3927345059123 37.9642781355522 1.48541569273518 0.138421281248034 -20.6850328889224 103.526207343888 -0.199804797448166 0.841760555873452 GPD1 other 1 1 1 1.48541569273518 -0.199804797448166 6.53133281964456e-39 101.469668286539 6.89695388432145 14.7122439831309 9.84823286941721e-38 -48.2005940575445 32.5600138136027 -1.48036159731012 0.139766815087777 PROSER3 other 9.9687732826235e-35 1 1.50421908847479e-33 14.7122439831309 -1.48036159731012 0.293405501191071 224.263013393442 202.421743975739 1.1078998184124 0.268739726316939 -393.32974471208 524.953071569142 -0.749266488786082 0.454248756767903 CYP2S1 other 1 1 1 1.1078998184124 -0.749266488786082 0.0612561943963551 226.103971674618 114.184552723334 1.98016252007802 0.0485442437500629 -213.282566641792 298.156130015263 -0.715338526264322 0.474923115164126 AXL other 1 1 1 1.98016252007802 -0.715338526264322 8.13776442588616e-05 10.1783073673392 3.47187797698584 2.93164317260242 0.00361462585336377 -43.1188776885253 16.2077055819312 -2.66039369178791 0.00819824503532665 NFKBID other 0.707334483898025 1 1 2.93164317260242 -2.66039369178791 0.0934712356660714 156.821877563195 74.1826694061858 2.11399615056341 0.0352937992042175 6.70794621330779 183.002498266728 0.0366549433851493 0.970783133255684 TMC4 other 1 1 1 2.11399615056341 0.0366549433851493 0.57995096554988 -14.9272392737821 28.3767738685073 -0.526037221248341 0.599229001592594 -72.8868164598568 72.1306667111993 -1.0104830550324 0.313032153411546 LAIR1 other 1 1 1 -0.526037221248341 -1.0104830550324 0.589627353340015 -6.09768973766426 6.3729112669693 -0.956813845701648 0.339388052506507 -10.0450836614507 16.1992459293608 -0.620095756632977 0.535638839785996 TTYH1 other 1 1 1 -0.956813845701648 -0.620095756632977 0.0435545439732164 117.68141895784 100.709290870257 1.16852594175693 0.243469935963571 -469.538543904472 255.992042229495 -1.83419195305897 0.0675597539678156 LENG8 essential 1 1 1 1.16852594175693 -1.83419195305897 0.126029387750404 26.037304887701 14.191165969981 1.83475444813896 0.0674702558654778 49.7688973478999 36.7266256135278 1.35511761607546 0.176335883493754 CDC42EP5 other 1 1 1 1.83475444813896 1.35511761607546 0.441559802070748 -1.78046061690108 1.78944765972652 -0.994977755970347 0.320498848427409 2.36816296920642 4.65058143278705 0.509218686616396 0.610949896490514 LAIR2 other 1 1 1 -0.994977755970347 0.509218686616396 1.98496728212346e-09 54.6682034120788 11.3754123793298 4.80582167829062 2.38315210606541e-06 -82.7709896139807 28.1843241889203 -2.9367739690746 0.00355924157441781 ZNF526 other 2.37163890868111e-05 1 0.0278161513819954 4.80582167829062 -2.9367739690746 7.94136887151338e-06 105.390491264505 21.3523666461489 4.93577564543709 1.28878157127788e-06 38.2118309039668 110.162643018967 0.346867412189701 0.72891963672924 TRAPPC9 other 0.0765071477081599 1 0.0152836606537844 4.93577564543709 0.346867412189701 0.538246851015971 15.3316885325409 13.7707340823667 1.11335303120645 0.266392439804814 11.9910674271121 36.5395369368714 0.328166923621084 0.743000077189689 NLRP7 other 1 1 1 1.11335303120645 0.328166923621084 1.05391539745085e-13 468.863898181199 67.3595836137931 6.96061158675557 1.94446546911728e-11 -375.094079191131 189.923570008172 -1.97497382328582 0.0491357505801499 ZNF146 other 1.41604072801497e-09 1 2.67558448550538e-07 6.96061158675557 -1.97497382328582 2.1642858106902e-30 28.8605744621071 2.33045071377352 12.3841170686572 4.99262369493253e-29 -19.7704852099549 9.81441592474956 -2.01443319312548 0.0448030133518646 ZNF283 other 3.27261657434465e-26 1 7.57181309573467e-25 12.3841170686572 -2.01443319312548 0.145377350086299 12.3457195258205 7.94749952283276 1.55340928179384 0.121313805927797 -17.7527344184341 23.4447445389663 -0.757215946154935 0.449477686135377 PPP1R14A other 1 1 1 1.55340928179384 -0.757215946154935 9.21835281966604e-10 2377.16960979277 459.785846632168 5.17016699666818 4.1294131549561e-07 -3649.03547748003 1356.34631822932 -2.69034200811174 0.00751253250778498 SPINT2 other 1.11597379234877e-05 1 0.00501145580485473 5.17016699666818 -2.69034200811174 0.209719182766486 4.61944782129047 313.848202390848 0.0147187327698557 0.988265746665336 -1578.31423708062 925.837228165638 -1.70474267945321 0.0892130023918088 C19orf33 other 1 1 1 0.0147187327698557 -1.70474267945321 4.73337767929921e-08 180.908010034502 41.0467148988259 4.40736878652563 1.42987716290938e-05 -328.108109817369 121.085851241894 -2.70971468963706 0.0070969411186428 YIF1B other 0.000530895640510199 1 0.158659169996425 4.40736878652563 -2.70971468963706 0.124818307820943 6.67236827928025 9.03387398311877 0.738594349638775 0.460694713871473 -39.0346137269692 23.575816235413 -1.65570571712956 0.0987617052814719 DNAAF3 other 1 1 1 0.738594349638775 -1.65570571712956 0.0899710400361123 -171.074531740629 82.8837065500322 -2.06403090379846 0.0398205574297945 232.961370758531 409.155207626385 0.569371637990387 0.569503402003987 PSCA other 1 1 1 -2.06403090379846 0.569371637990387 0.00206133739980576 3849.86175760236 1184.82789113572 3.24930041435138 0.00127986237143113 -6515.52541285699 5849.53911329827 -1.1138527816738 0.266178275171292 LY6D other 1 1 1 3.24930041435138 -1.1138527816738 2.82939169454847e-12 7676.56650141585 2283.08543319204 3.36236497759221 0.0008668110173277 -18868.846252577 4200.65750741336 -4.49187924016111 9.88207278610359e-06 EEF2 essential 3.68726325633556e-08 0.145503639702589 1 3.36236497759221 -4.49187924016111 7.62319862501334e-07 81.1144587219655 73.2964386280222 1.10666302811272 0.269270869127595 -571.924838274117 135.822822505586 -4.21081544120167 3.31106388125243e-05 CHAF1A essential 0.00795861936451393 0.480534701086166 1 1.10666302811272 -4.21081544120167 3.18984788573694e-10 278.249995178926 99.8950383642029 2.78542357794055 0.00566441601394727 -791.334771310247 185.111668709953 -4.2749048551346 2.52657448958287e-05 UBXN6 other 3.93053056480506e-06 0.367945042917954 1 2.78542357794055 -4.2749048551346 0.448420168388197 2.3780803608722 89.0782830366849 0.0266965222027555 0.978718427626421 187.956961442244 165.256942492235 1.13736196862698 0.25623790713706 PLIN4 other 1 1 1 0.0266965222027555 1.13736196862698 0.257770387965042 38.3141759251524 27.9902101356445 1.36884202510365 0.172008758151674 -9.69384751340721 51.927095909862 -0.186681872797862 0.852028364949419 SEMA6B other 1 1 1 1.36884202510365 -0.186681872797862 0.00072503902246291 71.9442330129943 22.4206592717718 3.20883664217555 0.00146906700666065 -62.9294944645834 57.3081506144954 -1.09808977937365 0.27299863781045 ZNF444 other 1 1 1 3.20883664217555 -1.09808977937365 6.6347715049933e-12 888.773253578774 120.613607372942 7.36876437855519 1.52416865791456e-12 -211.621124552316 229.543765046415 -0.921920595445166 0.357275554220012 NXN other 8.57345173875234e-08 1 2.13459820540934e-08 7.36876437855519 -0.921920595445166 2.75809724980656e-14 370.588287840066 45.0716660741627 8.22220077754139 5.28958491832146e-15 -69.8696304934408 85.7773857603655 -0.814546047003975 0.415947572964426 FAM57A other 3.74466863606236e-10 1 7.61911811635024e-11 8.22220077754139 -0.814546047003975 1.80838228796782e-13 290.185203193196 38.4018370340814 7.55654483236462 4.53893330672322e-13 -172.324581092196 73.0838124279452 -2.35790355438961 0.0189894521035874 GLOD4 other 2.41871131015696e-09 1 6.39535702917302e-09 7.55654483236462 -2.35790355438961 1.59788341078155e-05 90.4790406349084 21.3429634570407 4.23929136256198 2.93981664184748e-05 -178.36851881331 105.165855653534 -1.69606872596502 0.0908484696879421 MFSD3 other 0.149833527428986 1 0.319322883637473 4.23929136256198 -1.69606872596502 0.568295774419178 5.36515007099925 5.44041269983263 0.986166007436219 0.324799040193463 -7.50808422729128 26.807226552108 -0.280076874521019 0.779600056620839 GPT other 1 1 1 0.986166007436219 -0.280076874521019 2.76378073135982e-08 186.217821782179 31.1542513201841 5.97728444405058 6.06886055957786e-09 -47.5906243685599 153.510242564351 -0.310015954463819 0.756751253148846 KIFC2 other 0.000314048404504416 1 7.90165644857037e-05 5.97728444405058 -0.310015954463819 0.00243613443564981 149.75002271224 43.0351082456894 3.47971757982599 0.000571991821017745 -20.5601301512663 82.1310600358757 -0.250333188714299 0.802491344442 SLC43A2 other 1 1 1 3.47971757982599 -0.250333188714299 3.05104989999553e-09 40.3548070028441 6.4635283845614 6.2434640341697 1.36376978191957e-09 -17.1269043916823 12.325316111283 -1.38957120750873 0.16562817914181 RILP other 3.6219013362847e-05 1 1.80863148478173e-05 6.2434640341697 -1.38957120750873 0.0569953470120035 43.9236798730024 18.4176240016034 2.38487222180116 0.0176669936951299 -6.34356128171682 34.9049048916434 -0.181738391822278 0.855903100212544 SERPINF2 other 1 1 1 2.38487222180116 -0.181738391822278 1.7420624839659e-09 202.163261336184 36.3165600821465 5.56669631922461 5.49951933594822e-08 -219.446684861059 68.868242218225 -3.18647140964759 0.00158225966422505 WDR81 other 2.08611982454917e-05 1 0.000691784537268927 5.56669631922461 -3.18647140964759 1.37097708184503e-19 185.255773248982 19.0034906214302 9.74851288847266 7.98561824261262e-20 -60.3014006980336 36.1526165051532 -1.66796781332378 0.0963033755472553 SRR other 1.98448932597068e-15 1 1.18450675392673e-15 9.74851288847266 -1.66796781332378 1.76987387827392e-16 460.282741316538 51.5560476013961 8.92781279269503 3.50391441840334e-17 -82.4602971563511 98.0812448925984 -0.840734609829304 0.401126356391107 TSR1 essential 2.48100920256438e-12 1 5.122022096822e-13 8.92781279269503 -0.840734609829304 0.0102323958820378 123.400429264071 40.7077641194243 3.03137330023951 0.00263321308573441 -14.7524713637116 77.1489652962974 -0.191220599097518 0.848474033737513 TRPV3 other 1 1 1 3.03137330023951 -0.191220599097518 4.05106436917382e-05 55.0128197212231 14.250058853841 3.86053280800273 0.000137134343055169 -12.5301251871633 26.1660616826425 -0.478869359062746 0.632361709803518 HSD11B1L other 0.365275785470088 1 1 3.86053280800273 -0.478869359062746 0.00026794086150291 44.4473939208891 12.2496344428815 3.62846696594431 0.00033174628673998 -41.1591694702105 23.2293694664049 -1.77185909112756 0.0773695238212124 CYB5D2 other 1 1 1 3.62846696594431 -1.77185909112756 0.00190486940483316 -23.8194722412041 68.0850125300388 -0.34984898079728 0.726682177024968 -457.43855780846 128.179161639958 -3.56874356140163 0.000413632700601076 GGT6 other 1 1 1 -0.34984898079728 -3.56874356140163 0.0174636231230859 177.400685572996 111.498004655061 1.59106601164583 0.112582088599062 -523.657947776568 265.085738083826 -1.97542859741091 0.0490784949503734 C19orf48 other 1 1 1 1.59106601164583 -1.97542859741091 0.877394058110178 -311.606863222566 992.593326998362 -0.313932055300912 0.753777195035025 -1092.03669220394 2359.8837980864 -0.462750196890823 0.643857948281732 KLK1 other 1 1 1 -0.313932055300912 -0.462750196890823 0.775307289902787 -224.675142576918 449.846994960925 -0.499447912498413 0.617807083782149 -658.677106869122 1086.02840299716 -0.606500810707474 0.544612263596135 KLK5 other 1 1 1 -0.499447912498413 -0.606500810707474 0.127565432461752 764.135911220893 375.663049936786 2.03409920499095 0.0427660167797879 326.663783646337 906.932238645562 0.360185435831663 0.718946079409595 KLK6 other 1 1 1 2.03409920499095 0.360185435831663 0.109879177395945 424.332393857138 204.0474164324 2.07957739076651 0.0383626536713572 382.451071236953 495.498902865615 0.771850490536157 0.440774387536581 KLK11 other 1 1 1 2.07957739076651 0.771850490536157 0.0637597102757899 511.178692586223 269.551368160782 1.89640548320762 0.0588097563708451 1151.96020772099 654.565539347771 1.75988520396115 0.0793856979214507 KLK13 other 1 1 1 1.89640548320762 1.75988520396115 0.714151630298198 -4.31076670931719 21.2844959241934 -0.202530833930499 0.839631270537303 -55.9070546458296 68.1731486892955 -0.820074409363581 0.412787943986664 ZNF83 other 1 1 1 -0.202530833930499 -0.820074409363581 0.0935950030357096 227.454213475609 322.810209296987 0.70460662929762 0.481569159601295 -1662.07137865338 884.724705956861 -1.87863113515722 0.0612066479992583 KRT80 other 1 1 1 0.70460662929762 -1.87863113515722 0.4974911670444 5955.79087412952 5035.43811672651 1.1827751103416 0.237779068549399 3479.73114591402 13668.3542854358 0.254583037083098 0.799209197919677 KRT1 other 1 1 1 1.1827751103416 0.254583037083098 0.346774078528145 10.4203509901548 10.0044903257413 1.04156740132413 0.298398558776545 25.1605248160456 18.2519670249728 1.37851031516879 0.169008733849338 ACER1 other 1 1 1 1.04156740132413 1.37851031516879 2.34203176314826e-21 662.430582738806 73.0060708179634 9.07363696356897 1.2780923892416e-17 -799.378643432877 295.271891171565 -2.70726292388057 0.00715421723014905 OTUB1 other 3.42920290760168e-17 1 1.87304439643357e-13 9.07363696356897 -2.70726292388057 0.117516451296432 25.1059739627692 12.5307340666068 2.00355173362702 0.0459742612392706 0.203460043221572 51.0458969318409 0.00398582560892686 0.996822302710697 RCOR2 other 1 1 1 2.00355173362702 0.00398582560892686 0.838121633701579 74.2976555826488 166.32969721145 0.446689056904833 0.65540173105245 -54.0182327177855 310.205798992904 -0.174136759832208 0.861868096565763 ANGPTL4 other 1 1 1 0.446689056904833 -0.174136759832208 2.17593626783371e-06 12.8172274682775 36.9372970823296 0.346999604213302 0.728819703794142 -316.831207774862 68.8882619650051 -4.5992045486038 6.11739726823275e-06 NDUFA7 other 0.0219182060258889 0.0905374795698448 1 0.346999604213302 -4.5992045486038 0.000876765664150109 118.60458574848 60.2471393853473 1.96863431124709 0.0498578734347518 -237.798115449055 112.241198753218 -2.11863485146746 0.0348915800940167 CD320 other 1 1 1 1.96863431124709 -2.11863485146746 3.96041806577036e-09 333.378972215947 54.0176531732956 6.17166708717287 2.04310127417583e-09 -60.0152044273774 145.961355054807 -0.41117187768531 0.681221730364755 SPRYD3 other 4.68279832096688e-05 1 2.69709799203952e-05 6.17166708717287 -0.41117187768531 0.649884833318018 -293.179941269485 1137.76476368619 -0.257680630150318 0.796819024523731 -2849.18655974701 3074.35952666207 -0.926757763702565 0.354750748544834 IGFBP6 other 1 1 1 -0.257680630150318 -0.926757763702565 5.18582021222514e-06 67.4378610131489 18.0762704419909 3.73073976900079 0.000225820429219643 -61.7957029483706 36.9686744445713 -1.67156934558266 0.0955868115592082 ZNF558 other 0.0507484365968352 1 1 3.73073976900079 -1.67156934558266 9.43542031827197e-08 644.061921048219 122.537303251678 5.25604778265266 2.75549202798333e-07 -793.698511732802 620.962565290067 -1.27817449247049 0.202150309459588 NDUFV1 other 0.00104336877879451 1 0.00337079339783201 5.25604778265266 -1.27817449247049 6.76060721358638e-07 215.473700259695 41.2010633008052 5.22980920872214 3.13985315725371e-07 -71.5841686659329 212.93782317792 -0.336174041781769 0.736968534043108 CDK2AP2 other 0.00707835575262494 1 0.0038290509252709 5.22980920872214 -0.336174041781769 0.0538131503127921 18.2912884647643 18.2411897366483 1.00274646165296 0.316770339426166 -177.912626041414 92.4379407105718 -1.92467102440618 0.0551914538647757 NUDT8 other 1 1 1 1.00274646165296 -1.92467102440618 1.35423138513817e-07 669.195781646675 161.42504603946 4.14555112769237 4.36254169359922e-05 -1654.2120815436 534.134879244153 -3.09699318622378 0.00213081176162157 PRDX2 other 0.00148328963614184 1 0.468013472889325 4.14555112769237 -3.09699318622378 2.72508340857105e-17 79.2326913073661 8.70255724666506 9.10452974471719 9.57274555190086e-18 -31.8763354200868 19.4257336569864 -1.64093341250062 0.101793715042761 ZNF232 other 3.85408546474204e-13 1 1.40393886264178e-13 9.10452974471719 -1.64093341250062 8.72810743209629e-08 100.395958204558 17.7343375212022 5.66110564234666 3.34608923117242e-08 -40.5161543696351 33.3668814024693 -1.21426254617361 0.225542814814445 MIS12 essential 0.000966812460253306 1 0.000424284114512663 5.66110564234666 -1.21426254617361 0.423438001902446 -4.23596424144932 3.22680898527536 -1.31274093408657 0.190213883633517 -1.49120375253818 7.62954047298206 -0.195451319488883 0.845164077955735 CD300C other 1 1 1 -1.31274093408657 -0.195451319488883 0.124419817737494 -22.4542140238917 10.9684135727158 -2.04717062089517 0.0414602547288211 -5.88713336607687 25.9339662370191 -0.227004743982174 0.820565458257656 CD300A other 1 1 1 -2.04717062089517 -0.227004743982174 0.520548551248251 32.0987623092815 29.3475330704689 1.09374652486825 0.274888800360531 34.8786135885051 69.6931863462897 0.500459448290987 0.617095613284638 HID1 other 1 1 1 1.09374652486825 0.500459448290987 0.0002818853940365 78.4508200827596 19.1569220804785 4.09516830277779 5.34873536974333e-05 32.8871345225697 45.418906003342 0.724084691078861 0.469542766254194 MRPL58 other 1 1 0.569007815271709 4.09516830277779 0.724084691078861 0.00442508931654418 283.451701784443 89.4742592147851 3.16796924916708 0.00168317440058492 -97.3635009686346 212.133397626341 -0.45897299556826 0.646565154107047 ATP5H other 1 1 1 3.16796924916708 -0.45897299556826 0.000114421099319007 16.5802796625583 4.44029721036267 3.73404726689548 0.000223111300316413 19.7896659659657 8.48898079814556 2.33121813283979 0.0203644803948159 TMEM88 other 0.979673452369342 1 1 3.73404726689548 2.33121813283979 0.0202993110945333 774.899080300328 378.745833701423 2.04596067163924 0.0415824965159025 -1446.17365907855 930.748962982331 -1.55377412878837 0.121232936847295 EVPL other 1 1 1 2.04596067163924 -1.55377412878837 1.08028097795309e-21 570.138452919692 58.1048533610313 9.81223460589718 5.00116152732771e-20 -337.955606871414 142.419593244579 -2.37295725378907 0.0182405659216229 SRP68 other 1.58552839134176e-17 1 7.43022568115078e-16 9.81223460589718 -2.37295725378907 0.000243938653728504 24.745527578717 6.00814023553831 4.11866677684163 4.85633385244352e-05 15.5945075685405 14.4937815491099 1.07594470881881 0.282762509205144 MGAT5B other 1 1 0.518850708795066 4.11866677684163 1.07594470881881 0.462468915397276 -27.4594381558616 45.5706157605429 -0.602568951452203 0.547222241470635 -127.350069265667 107.414738098626 -1.18559214051928 0.236663038210027 TMC8 other 1 1 1 -0.602568951452203 -1.18559214051928 0.0275057177686083 412.059279200967 163.934798062555 2.51355590192468 0.0124428385390869 -176.420492752907 386.411574767158 -0.456561097734233 0.648296281326416 TK1 other 1 1 1 2.51355590192468 -0.456561097734233 0.000857447525428726 40.758072212502 11.5433459070874 3.53087159828395 0.000477488683638325 -46.6621368633838 53.8114969789717 -0.867140657350942 0.386540001171435 TMEM68 other 1 1 1 3.53087159828395 -0.867140657350942 0.531743282853999 36.2038709067455 52.2600102658441 0.692764328261289 0.48896787312179 141.307225197361 151.892513121029 0.930310667022584 0.352922656426968 GSDMA other 1 1 1 0.692764328261289 0.930310667022584 0.107494075742524 -225.780065751103 167.26151198338 -1.34986263769717 0.178020115826112 -845.865475666723 487.672741365361 -1.73449406521782 0.0837994603535036 KRT24 other 1 1 1 -1.34986263769717 -1.73449406521782 0.131705879254333 83.9894718962505 51.3805289022844 1.63465565050881 0.10310764476612 196.219498894444 149.841177551359 1.30951653010862 0.191301800312235 TMEM99 other 1 1 1 1.63465565050881 1.30951653010862 0.0700146105573699 38.1532339410009 20.0817247013975 1.89989826612581 0.0583452566175519 -59.925736713243 51.8126003004473 -1.15658616563828 0.248304168260048 GHDC other 1 1 1 1.89989826612581 -1.15658616563828 5.56321623849556e-08 251.624289035066 51.2166472770153 4.91293949160917 1.44468453159206e-06 -231.945006884756 138.169795449802 -1.67869544953494 0.0942030874130317 FAM234A other 0.000621856311139034 1 0.0170819499015445 4.91293949160917 -1.67869544953494 0.455232517091287 -15.3874971828789 14.7372367627822 -1.04412363257533 0.297221256507352 21.8253818282683 35.7946409109414 0.609738812091196 0.542470266082941 SOST other 1 1 1 -1.04412363257533 0.609738812091196 2.39763796281621e-12 291.19834477115 58.8564753197041 4.94760080669768 1.21817955434469e-06 -700.138868121037 167.203313689264 -4.18735043386876 3.65549020365987e-05 ZNF598 other 3.13011636045657e-08 0.529826750118462 0.0144658822078431 4.94760080669768 -4.18735043386876 0.0885375768727646 5.11774558364589 7.86529817471579 0.650674071085783 0.515723814986604 -40.8088991626143 22.1847126723016 -1.83950541823179 0.0667670837324222 RAB26 other 1 1 1 0.650674071085783 -1.83950541823179 1.12255703401606e-06 172.744006438314 39.9031253512082 4.32908462477321 2.00513126777195e-05 -200.604878969512 113.386841672114 -1.76920774942837 0.0778116556250769 MLST8 essential 0.0115814209199437 1 0.220363926328137 4.32908462477321 -1.76920774942837 4.2572307513925e-05 58.1076994483685 21.2567568845534 2.73361076498896 0.00661404233908115 -162.99031466251 60.1639125489244 -2.70910430783517 0.00711086425627842 E4F1 essential 0.382852761472728 1 1 2.73361076498896 -2.70910430783517 0.000793750713809063 18.054826156655 5.11120135995524 3.53240361416971 0.000472568820440219 -5.52327414808522 14.46645287004 -0.381798786316438 0.702864819181287 DNASE1L2 other 1 1 1 3.53240361416971 -0.381798786316438 0.493584919380896 -14.1813651849918 62.0159232041853 -0.228672967397424 0.819269630665947 -207.816027860672 175.526332665012 -1.18395926528747 0.237310644987179 ECI1 other 1 1 1 -0.228672967397424 -1.18395926528747 1.71169068517436e-12 193.979343743823 31.2072042220106 6.21585139007768 1.59051450261251e-09 -225.908042987484 88.6769217450111 -2.54754042587403 0.0113159538600278 CASKIN1 other 2.24334181198952e-08 1 2.10472784130714e-05 6.21585139007768 -2.54754042587403 0.104214226133014 -354.138088218541 167.811460774181 -2.11033314759767 0.0356054264246232 -428.114378690268 480.576549949185 -0.890834933031033 0.373687018937503 ABCA3 other 1 1 1 -2.11033314759767 -0.890834933031033 4.3828836214001e-11 105.00629343213 38.487024231719 2.72835573880481 0.00671674125221203 -619.026754516142 110.218701617642 -5.61634954350666 4.23819498612555e-08 KCTD5 other 5.54916895305466e-07 0.000641959394548437 1 2.72835573880481 -5.61634954350666 9.79240397106126e-08 947.382331907488 339.288102714149 2.79226511135777 0.00554884549783575 -4023.00749054825 971.649403973588 -4.14039001526275 4.43979068785752e-05 SRRM2 essential 0.00108157101860372 0.641638550209169 1 2.79226511135777 -4.14039001526275 0.0109579502259551 11.6256507436471 5.68544875238393 2.04480793864732 0.0416941884406555 -26.0265857580159 16.2761281595817 -1.59906493134205 0.110796118055331 ZNF597 other 1 1 1 2.04480793864732 -1.59906493134205 0.0100191955507096 -20.6986398505452 9.10336830693512 -2.2737341995464 0.023644074234021 -67.4731203001149 26.1615826582275 -2.57909168499389 0.0103521988751781 NLRC3 other 1 1 1 -2.2737341995464 -2.57909168499389 1.0349440628106e-15 90.1759599180297 12.6067941713423 7.15296519419799 5.81501544662259e-12 -192.79319357555 58.7596377031114 -3.28104803078699 0.0011483380213992 SDHAF2 other 1.43774429205648e-11 1 8.07182294145682e-08 7.15296519419799 -3.28104803078699 4.06728640675516e-34 1531.34796416628 119.18222678359 12.8487947028116 9.39086154637802e-31 -1411.57832698438 555.502403804863 -2.54108410209551 0.0115227596484787 DDB1 essential 6.17902150914244e-30 1 1.42788049812678e-26 12.8487947028116 -2.54108410209551 3.76015949481074e-28 198.261285005201 17.9232389261647 11.0616884493893 2.65671593711074e-24 -248.152202515549 83.5393210560843 -2.97048383178685 0.00319828709446459 VPS37C other 5.65979207158913e-24 1 3.99729479897682e-20 11.0616884493893 -2.97048383178685 0.720971559642733 1.92081403398835 4.79410412452482 0.400661726173654 0.68893656263554 -13.1990448336119 22.345079775192 -0.590691327415433 0.555144205739996 VWCE other 1 1 1 0.400661726173654 -0.590691327415433 0.0425057861003943 31.9470657291398 12.6644728498374 2.52257366792412 0.0121406625739742 38.5275111043845 44.5314784994731 0.865174757331276 0.387599204766482 RAB3IL1 other 1 1 1 2.52257366792412 0.865174757331276 0.0553545811903523 3364.54424204905 1426.03236860607 2.35937438456454 0.0189137432220678 6084.9712689286 5099.14421858118 1.19333186277711 0.233634582156701 BEST1 other 1 1 1 2.35937438456454 1.19333186277711 0.035322250685958 3934.33523958083 1537.01287815264 2.55972822056609 0.0109404283865013 6509.89361643076 5495.98347418852 1.18448202164435 0.237112427507289 FTH1 other 1 1 1 2.55972822056609 1.18448202164435 0.800399980350658 43.8082098219792 68.1475805339215 0.642843215837619 0.520796463731685 2.9238955611596 249.825021175926 0.0117037738950119 0.990669408885776 BSCL2 other 1 1 1 0.642843215837619 0.0117037738950119 4.75639585942898e-05 165.787123810444 45.6809870632031 3.62923689851676 0.000331891731800387 -267.945956717067 170.889875042679 -1.56794518487504 0.117904302141271 POLR2G essential 0.425554737543111 1 1 3.62923689851676 -1.56794518487504 3.26356797345781e-05 1628.09561611276 398.416140129273 4.08641983124605 5.58055364881146e-05 -1430.43936022471 1559.85412111888 -0.917034061620234 0.359835365157633 SLC3A2 other 0.296919414225191 1 0.592319964284848 4.08641983124605 -0.917034061620234 0.863354766566025 3.5830194083744 6.6506833926706 0.538744546511277 0.590447308208137 2.51895701687385 25.8225664895539 0.0975486699934668 0.922353320524198 HRASLS5 other 1 1 1 0.538744546511277 0.0975486699934668 1.49313234715949e-07 141.719407905173 26.1123854909259 5.42728690775575 1.14842583664864e-07 -41.8547943215276 106.315935699238 -0.393683167497415 0.694083014891835 C11orf84 other 0.00163169502897589 1 0.00142645973170127 5.42728690775575 -0.393683167497415 1.75960733930678e-06 32.2347246496401 15.6433815925099 2.06059824463236 0.0401836074392195 -183.471082583641 53.2709917776156 -3.44410863138343 0.000652610908263 ATG16L2 other 0.0178529760646066 1 1 2.06059824463236 -3.44410863138343 1.3781395240933e-18 102.371219667689 15.746778561871 6.50108968418273 3.10899755475367e-10 -201.097050224789 54.8130503756364 -3.66878049746661 0.000285926320689053 C2CD3 other 1.97597644964497e-14 1 4.18346710967654e-06 6.50108968418273 -3.66878049746661 1.56224123417145e-05 -24.7443026207935 72.254053000537 -0.34246248609209 0.732227699363343 -437.13842832297 103.499577765879 -4.22357692426337 3.13832369300809e-05 TRANK1 other 0.146569472589966 0.455872899646355 1 -0.34246248609209 -4.22357692426337 1.51666060939155e-13 1964.55875297364 524.435599934525 3.74604384831792 0.000213031903471504 -3032.44224856565 751.222400744987 -4.03667708199114 6.78907548856931e-05 RPSA essential 2.03171855234092e-09 0.974979130913438 1 3.74604384831792 -4.03667708199114 0.0584928416703507 -134.045184215261 62.066876985707 -2.15968952725186 0.0315391780809898 -179.89532415089 88.9070618809398 -2.02340871855374 0.0438619508597563 ENTPD3 other 1 1 1 -2.15968952725186 -2.02340871855374 1.81349026479735e-09 2217.69238253111 514.994405690753 4.30624557864188 2.21289494960452e-05 -1400.54982990721 736.67562248716 -1.90117575111102 0.0581799742134007 CTNNB1 og 2.17002245085651e-05 1 0.242489028577663 4.30624557864188 -1.90117575111102 0.0393250995061065 7.52096249812904 5.34963038836379 1.40588451016882 0.160731677131886 -8.15133625425231 7.65239826467282 -1.06520021205415 0.287590915287017 ULK4 other 1 1 1 1.40588451016882 -1.06520021205415 8.13913757562031e-80 334.854317659881 11.8188765160023 28.3321614543057 5.1845652809129e-80 -70.1335115586998 177.737614452583 -0.394590147812579 0.693481799778989 FADD other 1.25017153161528e-75 1 7.96349227148222e-76 28.3321614543057 -0.394590147812579 0.183864839477324 166.916179162921 90.4707343210765 1.84497429379255 0.065976875255281 116.237879864644 437.391884023117 0.265752255838611 0.79060331190676 LTBP3 other 1 1 1 1.84497429379255 0.265752255838611 0.457198467560596 4.19178004886026 3.34628843690157 1.25266549130521 0.21125662320486 4.19196937315458 13.988944278172 0.299663026015168 0.764631839191214 NAALADL1 other 1 1 1 1.25266549130521 0.299663026015168 0.408070751176945 7.20702975668185 25.7516827565387 0.27986636154299 0.779763722857677 -129.866193234569 107.653258809912 -1.20633777992619 0.228592507032042 SAC3D1 other 1 1 1 0.27986636154299 -1.20633777992619 0.676229816954429 -0.126656132468792 41.8748798570782 -0.00302463273688374 0.9975886104861 -150.575902658186 175.055250622152 -0.860162160935105 0.390353841132283 BATF2 other 1 1 1 -0.00302463273688374 -0.860162160935105 5.70349545169346e-06 419.47590792938 103.036557276767 4.07113668212558 5.91382149458452e-05 -754.275563342108 420.4620547361 -1.79392065192547 0.0737787266167971 SF1 essential 0.0556375981312697 1 0.626510249136284 4.07113668212558 -1.79392065192547 1.68294622450688e-12 153.067300991173 22.0164697421914 6.95239985263583 2.05555240142965e-11 -127.631746554127 89.8427737736949 -1.42061226733292 0.15641234668698 MAP4K2 other 2.20617420570607e-08 1 2.8270012176862e-07 6.95239985263583 -1.42061226733292 0.57716818541659 -8.55310884080543 51.6546486770138 -0.165582557618121 0.868591023633238 -209.501292735579 200.832812885649 -1.04316266712286 0.297667825891968 CCDC88B other 1 1 1 -0.165582557618121 -1.04316266712286 1.40412870362961e-06 214.41729218385 81.1194622085295 2.64322871905461 0.00861616147648088 -292.190212920664 148.832830310597 -1.96321075337274 0.0504874744422578 SCARA3 other 0.0143824903112781 1 1 2.64322871905461 -1.96321075337274 1.82968090762056e-11 151.875837287189 40.7426970238755 3.72768246535542 0.000228460484940149 -195.710089310634 74.7521093885275 -2.61812129331925 0.0092619413616101 PBK other 2.33814923184831e-07 1 1 3.72768246535542 -2.61812129331925 0.146022860208577 -12.5797020285852 23.5479725153431 -0.534215929646964 0.593563079667274 49.8127120760319 43.2043223921441 1.15295667928562 0.249788665753242 SCARA5 other 1 1 1 -0.534215929646964 1.15295667928562 0.00138041410808516 -2.08046954184236 3.18326646801129 -0.653564369413947 0.513861846379353 -18.890539389221 5.8404548694989 -3.23442947703863 0.00134615777664117 PNOC other 1 1 1 -0.653564369413947 -3.23442947703863 1.02774798944741e-15 420.718463312031 51.7531319018148 8.12933339203917 9.81250128069419e-15 -344.115872502224 222.646162205057 -1.54557289060879 0.12320544912848 COPS6 essential 1.42805583133718e-11 1 1.41005643403576e-10 8.12933339203917 -1.54557289060879 1.52447377109014e-38 773.479127896112 89.6208652106518 8.63056974598569 2.91206232101233e-16 -676.388910755043 165.584445435786 -4.08485778344045 5.57947441144709e-05 PAFAH1B2 other 2.32634697468355e-34 0.803444315248381 4.23297378982352e-12 8.63056974598569 -4.08485778344045 0.00913038808814315 47.0864292218794 15.5346871583924 3.03105101131321 0.00263722335748038 11.2482259314972 45.8720149997064 0.245208891119547 0.806452857820402 ANKS3 other 1 1 1 3.03105101131321 0.245208891119547 0.0914960550312642 29.1485813488585 14.017034113115 2.07951133696576 0.0383712765667999 -5.01726006956959 41.2428277058844 -0.121651699183898 0.903251703437058 NUDT16L1 other 1 1 1 2.07951133696576 -0.121651699183898 1.06369178940138e-09 27.3972835647038 4.69279950591978 5.83815343701413 1.38211323838857e-08 -21.40229157556 13.1550588384411 -1.62692480804565 0.104813509293578 KIAA1586 other 1.28366325144958e-05 1 0.000177795046986305 5.83815343701413 -1.62692480804565 0.00126134975149782 94.904235196415 27.8461110421195 3.40816838131776 0.000737610258686206 -144.111273049546 93.7071055819632 -1.53789055968115 0.125063557376623 RAB4A other 1 1 1 3.40816838131776 -1.53789055968115 5.04754803933097e-22 715.888328363699 91.7956435239723 7.79871790077648 9.03296367338755e-14 -469.241260526209 156.427501382417 -2.99973634034504 0.00291559805804843 SETD5 other 7.41989561781652e-18 1 1.28629402709039e-09 7.79871790077648 -2.99973634034504 1.16732699307311e-05 145.001385333006 31.049638388696 4.66998628189485 4.45006301701548e-06 -1.98882009163277 91.3584768404634 -0.0217694094780695 0.982645549193077 VASN other 0.110720965292984 1 0.0511000736243888 4.66998628189485 -0.0217694094780695 3.69400484580646e-15 483.226515700322 59.4772293359028 8.12456331769017 1.05931040701683e-14 -78.6370277488306 166.850082242358 -0.471303500076231 0.63775339690716 FAM83B other 5.08775287412924e-11 1 1.52191126176108e-10 8.12456331769017 -0.471303500076231 0.00560697723741449 12.4813887180088 5.11058723872745 2.44226116001431 0.0151415727411029 -8.9006620382576 9.5912018597007 -0.928002785099901 0.354112167443187 THAP9 other 1 1 1 2.44226116001431 -0.928002785099901 2.04683772870333e-08 624.481823763752 102.306102298426 6.1040525416768 2.98949033360423e-09 74.167790916616 344.278190777049 0.215429826528414 0.829569458679774 RNF187 other 0.000234240109672809 1 3.92789134932259e-05 6.1040525416768 0.215429826528414 3.37605232613379e-17 196.038674450763 36.4373020784893 5.38016437189771 1.61912976519956e-07 -286.984353555471 81.5258032739599 -3.52016591104397 0.000506327100801022 HOOK3 other 4.7690115158966e-13 1 0.00199881569513886 5.38016437189771 -3.52016591104397 7.42583783330963e-23 416.469421378675 42.8143337185903 9.72733627284829 9.68051967025483e-20 -351.150520627391 128.350295982267 -2.73587620456992 0.00657196155570776 MAPK1IP1L other 1.0971675398715e-18 1 1.43523384631198e-15 9.72733627284829 -2.73587620456992 0.00814426450942547 1169.84268993182 748.761308834207 1.56237064619861 0.119192172275873 -3399.31481818665 1736.69163982928 -1.95735082741621 0.0511779683147172 DDIT4 other 1 1 1 1.56237064619861 -1.95735082741621 2.37681716350395e-07 130.478178338982 65.0737047489096 2.00508298770509 0.0458148939522448 -404.685397325623 121.65883199235 -3.32639554973757 0.000984488898945776 RBPJ other 0.00256910167203142 1 1 2.00508298770509 -3.32639554973757 0.00255176365095891 39.5114364527295 26.2184185009217 1.50701067081298 0.132816507530326 -178.286111206295 63.2149786104823 -2.82031434835812 0.00510383760715772 LMBRD1 other 1 1 1 1.50701067081298 -2.82031434835812 8.48243201230614e-12 22.7278912247363 6.95837947321198 3.26626211062979 0.00121027678871009 -49.1135861393834 12.9995209460246 -3.77810738898059 0.00018903700740019 ZCCHC4 other 1.09313101342589e-07 1 1 3.26626211062979 -3.77810738898059 7.88763529779164e-14 136.212721331186 23.4284969068926 5.81397611090927 1.64389270470132e-08 -128.656498255685 50.3907304855265 -2.55317787648739 0.0111992819973236 TTC39C other 1.06230672190658e-09 1 0.000211059384356602 5.81397611090927 -2.55317787648739 8.74352351792341e-16 -0.663186523951789 6.07091810836385 -0.109239906075841 0.913081109668227 -64.6253728724339 8.59656488567223 -7.51758100263328 5.73058046545184e-13 GLYCTK other 1.21578694516725e-11 8.78497985353768e-09 1 -0.109239906075841 -7.51758100263328 0.106629720509131 92.245372727791 49.0737195375841 1.87973060931611 0.0610532102187904 143.772520139401 157.594083832381 0.912296430444169 0.362299465641026 GNG4 other 1 1 1 1.87973060931611 0.912296430444169 1.07544142499857e-05 102.569428846862 26.2806053325177 3.90285640490747 0.000115932666048359 -54.8484168314762 39.808688180968 -1.37780015714505 0.169227741632647 UBTD2 other 0.102306742760114 1 1 3.90285640490747 -1.37780015714505 0.00853443143340909 669.181924484002 215.184780894578 3.10980136096076 0.00204209906155651 673.25562029049 848.193932945589 0.79375198777056 0.42793358129127 POLR2J3 other 1 1 1 3.10980136096076 0.79375198777056 1.35318649394218e-13 238.095143441703 31.0588345005051 7.66593941050271 2.14343804201586e-13 -148.450280791953 80.1345004824424 -1.85251395963313 0.0648727131750388 NKIRAS2 other 1.81408181377889e-09 1 3.03446523608185e-09 7.66593941050271 -1.85251395963313 0.000680810202750472 186.909591733459 62.6503313543821 2.9833775447444 0.00307009819410518 -353.936952388799 161.643316270006 -2.18961699472677 0.029273782946041 DNAJC7 other 1 1 1 2.9833775447444 -2.18961699472677 8.50279681012051e-09 750.203306538339 119.503436928249 6.27767138604365 1.11793815017769e-09 -83.7516980617482 383.770271236612 -0.218233939257143 0.827385946889428 IRF2BP2 other 9.90745884315241e-05 1 1.48629877066124e-05 6.27767138604365 -0.218233939257143 6.85989350511945e-08 596.421842031021 140.100160824575 4.25711033107111 2.72672705912413e-05 -233.961106862 201.899510264168 -1.15879977398599 0.247404535917151 NT5DC2 other 0.000762957355639386 1 0.296831507656253 4.25711033107111 -1.15879977398599 0.000269346354025278 27.723750498351 17.9510191765321 1.54441094545736 0.123477139312848 -61.6518504542186 25.8959720346585 -2.38075058050361 0.0178623138255391 SMIM4 other 1 1 1 1.54441094545736 -2.38075058050361 0.00258131290196605 103.191689810939 34.0736205179064 3.02849207810805 0.00265773637596347 175.393806195703 109.423150700022 1.60289486341456 0.109944433592597 COA6 other 1 1 1 3.02849207810805 1.60289486341456 0.155458506284975 -6.47679670264673 5.6250628578305 -1.1514176581388 0.250430889844342 19.9472120471276 14.8002576490289 1.34776113498513 0.178700650435683 KIF5C other 1 1 1 -1.1514176581388 1.34776113498513 2.84465964152615e-13 184.037715948081 24.1096871197452 7.63335148374276 2.76901171768733e-13 -41.0433178553368 73.8866969463009 -0.555489953559111 0.57895512162537 MGAT2 other 3.79022450636944e-09 1 3.91482876646635e-09 7.63335148374276 -0.555489953559111 2.84578758473363e-06 145.70401074104 46.9235414007914 3.10513670518872 0.00207195441625991 -175.628900144859 93.3737555041856 -1.88092359781958 0.0608901646036099 BMI1 other 0.0284286738640391 1 1 3.10513670518872 -1.88092359781958 7.67370837419327e-06 111.336115200483 23.7491475485018 4.68800469461511 4.09406730341791e-06 30.458168048847 63.5744904469658 0.479094174954581 0.632199880305117 THAP11 essential 0.0740359383942166 1 0.0471390909315538 4.68800469461511 0.479094174954581 2.4086861631665e-05 221.252510682985 59.0244753009577 3.74848754783246 0.00021149853506026 -337.528591381805 155.300920919814 -2.17338435202249 0.0304937408698089 MMADHC other 0.221946424599416 1 1 3.74848754783246 -2.17338435202249 9.26965553420883e-19 184.553739781338 48.1012933463886 3.83677292110055 0.000150185453724666 -379.845474230541 69.4294629301308 -5.47095509888637 9.04285545689928e-08 PDHB other 1.3309371416017e-14 0.00136709888797403 1 3.83677292110055 -5.47095509888637 6.10274032880383e-08 60.9162247324328 17.2722594199071 3.52682432862397 0.000482052566412405 -52.3856469859326 24.9307993961471 -2.10124216851339 0.0364014641385266 PXK other 0.000680760683678068 1 1 3.52682432862397 -2.10124216851339 5.5215661268808e-05 107.895134776652 25.5771804778972 4.21841394401898 3.26221156644933e-05 -117.181093139368 121.04786910019 -0.968055811394571 0.333796270674712 PCMTD1 other 0.490149425083209 1 0.35342800110912 4.21841394401898 -0.968055811394571 4.712128690369e-09 15.7541841086707 9.85831252289804 1.59806093305302 0.111016337598065 -61.812256449663 14.2294997960503 -4.34395146249766 1.88112877814836e-05 KCTD6 other 5.55465730020697e-05 0.274945782214164 1 1.59806093305302 -4.34395146249766 2.93037374673514e-09 111.269785584613 17.6480737495172 6.30492523795451 9.56223925893856e-10 -16.104787138348 72.5506932250597 -0.221979782996549 0.824471219324641 MPLKIP other 3.48187008587069e-05 1 1.27340340211285e-05 6.30492523795451 -0.221979782996549 0.308212642099113 7.50502471728568 5.66117361436694 1.32570121118339 0.185884279508283 0.483719305885849 8.17134459918288 0.0591970268802787 0.952832127960462 ACOX2 other 1 1 1 1.32570121118339 0.0591970268802787 0.996948920632724 2.72447129623351 37.1334141743068 0.0733698033648254 0.941557685661595 3.33787127866666 53.5984133382516 0.0622755613604054 0.950382268970851 FAM107A other 1 1 1 0.0733698033648254 0.0622755613604054 8.59882233454533e-06 -21.088638772838 41.7755122415648 -0.504808622115607 0.614042895582794 -363.545914655693 77.9809941192207 -4.66198102193835 4.61519172391488e-06 IRF2 other 0.0825486944116352 0.0684894451828968 1 -0.504808622115607 -4.66198102193835 0.182881381620194 -8.97014873158348 7.07629989355331 -1.26763264227333 0.205850790861805 -18.3826599764109 10.1363732650688 -1.8135342390912 0.0706861058886339 CX3CR1 other 1 1 1 -1.26763264227333 -1.8135342390912 0.0833379677306041 307.94886852048 159.705251147158 1.92823258038476 0.0547107230962792 454.901807168702 228.768150356931 1.9884840020735 0.0476097157356155 XIRP1 other 1 1 1 1.92823258038476 1.9884840020735 0.0292387994233726 51.253896033193 25.3279534602351 2.02360984726467 0.0438543234648298 -85.5913283000164 76.6308207593762 -1.11693085695606 0.264875101463238 DEGS2 other 1 1 1 2.02360984726467 -1.11693085695606 1.07034977106809e-05 662.471984183459 226.123999449707 2.92968453501461 0.00363687746507525 -554.62558584885 326.387644597192 -1.69928486886609 0.0902373570380541 ARF4 essential 0.10186518771255 1 1 2.92968453501461 -1.69928486886609 3.53897256227258e-14 960.046670888824 248.014773143246 3.87092534336384 0.00013151504428602 -2143.03133996085 447.362925006838 -4.79036419910768 2.55425385658893e-06 SEPT2 other 4.7917694344052e-10 0.0380558282093184 1 3.87092534336384 -4.79036419910768 0.703703574505734 28.9398918918917 35.4273242046639 0.816880544652646 0.414612112160461 4.96989083200812 147.135226476296 0.0337777087855218 0.973075737052951 FILIP1L other 1 1 1 0.816880544652646 0.0337777087855218 0.000313871607579114 181.311633769368 44.8071918131765 4.0464850938516 6.54239885034995e-05 31.8477615886735 114.300921481009 0.278630838457106 0.780710387705295 MFSD2A other 1 1 0.691008166573962 4.0464850938516 0.278630838457106 6.87700913747565e-06 19.7752532646252 56.5508192202679 0.349689952104844 0.72680359594441 -437.167125373307 102.429412364631 -4.26798431506242 2.60843117940659e-05 DTYMK essential 0.0666244645238641 0.379683242474424 1 0.349689952104844 -4.26798431506242 0.578624655673042 243.785993293776 540.982663903935 0.450635500099992 0.652557451248452 -874.748879635865 1241.10721100641 -0.704813308534832 0.481439082874966 TAP1 other 1 1 1 0.450635500099992 -0.704813308534832 8.43920179882295e-05 59.2192010479769 30.1098154432626 1.96677396311401 0.0500812699169649 -143.147885720234 54.5373302241312 -2.62476885340631 0.00909084481971659 ING5 other 0.732498675785125 1 1 1.96677396311401 -2.62476885340631 4.56992108560381e-11 86.6865011201986 44.3941981413552 1.95265383202059 0.0517404494576295 -424.460850526698 80.4103581648607 -5.2786837444058 2.41915362888685e-07 ATG4B other 5.78049318118025e-07 0.00364759984163559 1 1.95265383202059 -5.2786837444058 1.87046041257486e-06 157.428995745015 39.6364606165314 3.97182274341001 8.82650135320277e-05 -258.837258053044 117.409120937024 -2.20457538551779 0.0281996792613151 BDKRB2 other 0.0189346707564953 1 0.920515826125517 3.97182274341001 -2.20457538551779 1.35302322826847e-05 -38.6905376003506 16.9417263320132 -2.28374233192758 0.0230415875656212 -214.457429782478 44.5339206683939 -4.81559733712554 2.26803613626018e-06 MLKL other 0.127711862516261 0.0338186868277756 1 -2.28374233192758 -4.81559733712554 0.000236171810189762 168.58088762644 55.5202785929975 3.03638403658339 0.00259105902567686 -174.518525085518 145.943549901143 -1.19579471106281 0.232662019987844 RFWD3 other 1 1 1 3.03638403658339 -1.19579471106281 0.0313142220156553 -30.2665221179108 12.2901396665899 -2.46266705985359 0.0143188206190487 -50.1781166578598 23.5356610418463 -2.13200370997201 0.033770220557085 RHOH other 1 1 1 -2.46266705985359 -2.13200370997201 0.407440657896598 11.6134023768683 13.6086401140237 0.853384488057753 0.394088459565371 32.194032161467 24.631208776676 1.30704231584251 0.192142674206483 KLHL30 other 1 1 1 0.853384488057753 1.30704231584251 0.0101853761335347 30.6513674371613 17.3972265889156 1.76185366561187 0.0790548401255351 -102.940984075214 53.3679608201239 -1.92889108920942 0.0546341287198757 COG7 other 1 1 1 1.76185366561187 -1.92889108920942 1.55712629916731e-07 25.4498510665075 17.865625743338 1.42451495582223 0.155271933616079 -201.786178111695 40.3687265345467 -4.99857675567275 9.52922270443882e-07 CDC40 essential 0.00170022620606079 0.0142833519116833 1 1.42451495582223 -4.99857675567275 8.76604358821844e-13 992.979118114207 145.366319891886 6.8308747091673 4.38338968044205e-11 -978.859692249026 565.197641770265 -1.73188920106447 0.0842753711437093 STIP1 other 1.15632880972189e-08 1 5.99209369316428e-07 6.8308747091673 -1.73188920106447 0.579382680915328 -63.1959128593659 66.2854613039623 -0.953390255060174 0.341114230838376 -136.101643835617 203.406932750769 -0.669110152712346 0.503909162620893 SCNN1B other 1 1 1 -0.953390255060174 -0.669110152712346 5.25053765535297e-08 882.023696171555 231.833373962091 3.80455877036833 0.000170164068383283 -494.004892092029 428.707658942854 -1.15231179519907 0.250053080461305 HR other 0.000587745185140211 1 1 3.80455877036833 -1.15231179519907 8.5078371418774e-17 1139.00338637399 127.005567719268 8.96813743545197 2.68101658856057e-17 84.235680744188 532.299244608675 0.158248732451452 0.874361565007215 RAB31 other 1.19603174540513e-12 1 3.9217910657464e-13 8.96813743545197 0.158248732451452 7.67274949824353e-22 286.86278462725 93.0766082738742 3.08200728353968 0.00223479963652707 -1030.17948343488 172.11781959382 -5.98531567426313 5.78897131777207e-09 REEP4 other 1.12689671880703e-17 8.80849875712199e-05 1 3.08200728353968 -5.98531567426313 0.703904122459318 -63.0514370227835 75.9207056281163 -0.830490661291129 0.406896466540849 -73.5962746645179 171.618002996178 -0.428837729024018 0.668337255306894 TNXB other 1 1 1 -0.830490661291129 -0.428837729024018 0.00126520571379209 -50.334902605031 65.863635132473 -0.764229039344568 0.445293911070215 -400.291841691366 121.795427226651 -3.28659171207189 0.00112670110498553 LGI3 other 1 1 1 -0.764229039344568 -3.28659171207189 0.151131766761999 231.903900497824 119.503146183179 1.94056732315945 0.053188830807447 237.600814227653 220.985931235567 1.07518525228818 0.283101797166146 BMP1 other 1 1 1 1.94056732315945 1.07518525228818 0.00567311830071197 250.096689510401 108.14848144523 2.31253075557108 0.0213866198915881 -580.208286152633 383.994807915028 -1.51097950855894 0.131786709750577 ATXN2L other 1 1 1 2.31253075557108 -1.51097950855894 0.00527745959220432 33.525925461821 22.5145897403704 1.48907556604091 0.137452333567593 -54.9345167291211 41.6341137373573 -1.31945925583207 0.18795888068665 PHYHIP other 1 1 1 1.48907556604091 -1.31945925583207 3.81688182930952e-28 144.895461535414 24.0499331522189 6.02477606146883 4.65251033736157e-09 -207.306942725805 44.4732799390042 -4.66138191314268 4.6170579491911e-06 POLR3D essential 5.74478884129375e-24 0.0685125229080468 6.07571324956048e-05 6.02477606146883 -4.66138191314268 0.00491444792099984 -54.6206857485056 62.4458381720294 -0.874688968030719 0.382405371187683 -724.10605517027 220.313941962321 -3.28670100820995 0.0011273776140648 FEN1 essential 1 1 1 -0.874688968030719 -3.28670100820995 0.442690092271583 -71.5111967701146 56.5038909977279 -1.26559774039261 0.206592429361462 -67.7716715600454 147.765229148852 -0.458644242291772 0.646805941815389 CAVIN2 other 1 1 1 -1.26559774039261 -0.458644242291772 1.15358092356862e-36 571.355368458838 38.8193992598533 14.7182949595443 9.89479071374588e-38 351.605905879106 163.91089382592 2.14510395051915 0.0327041014829992 MTCL1 other 1.75748053705679e-32 1 1.51123138571041e-33 14.7182949595443 2.14510395051915 1.94047702074675e-06 10.4523534213032 3.0163013138534 3.46528822346003 0.00060214985208833 -10.7062261937151 5.39932872079401 -1.98288097416315 0.0482381481455867 GBX2 other 0.0196240441108119 1 1 3.46528822346003 -1.98288097416315 0.537742948974531 30.8790996811387 32.2298560851244 0.958089902715727 0.338773784017642 -75.1650445550647 124.350318593845 -0.604462018312714 0.54598442883406 HFE2 other 1 1 1 0.958089902715727 -0.604462018312714 0.569928174872599 8.06227212739452 7.63962200941033 1.0553234332096 0.292076027448209 3.74654347630814 18.5524921345332 0.201942868329501 0.840090108267569 HEXIM2 other 1 1 1 1.0553234332096 0.201942868329501 9.87370640108486e-29 216.695314558807 41.9899762267142 5.16064389722003 4.79734394457129e-07 -660.567640494493 92.9040201228309 -7.11021589400694 1.05280608947016e-11 FNTA other 1.48786881757948e-24 1.61205668419671e-07 0.00580238750095898 5.16064389722003 -7.11021589400694 0.00781694349743754 1317.86367803984 471.266208186866 2.7964315182074 0.00548050938064198 -724.453000331636 1004.01792550218 -0.721553850713658 0.471097344866604 SERINC2 other 1 1 1 2.7964315182074 -0.721553850713658 0.179190586033692 630.241443227813 663.074669803962 0.950483364738008 0.342593084724159 2294.85953204063 1238.53236047568 1.85288621054621 0.0648308247264291 MYL1 other 1 1 1 0.950483364738008 1.85288621054621 1.89476636601105e-14 114.178108556655 23.909461906438 4.77543614337512 2.741046194519e-06 -190.234758003527 44.631017270079 -4.26238902089875 2.6687253815157e-05 TRAPPC11 essential 2.58029283723385e-10 0.38837960477198 0.0318920724732286 4.77543614337512 -4.26238902089875 0.0515513497210246 -5.55318140313992 2.37890160838399 -2.33434681937612 0.0201959735048915 -3.96466029007032 4.39907905387452 -0.901247793348568 0.368134382131596 GFRA2 other 1 1 1 -2.33434681937612 -0.901247793348568 2.28277583560445e-13 48.5401402604421 11.2487656213898 4.31515260377919 2.13401313043837e-05 -91.1005014817605 20.9883669983624 -4.34052356187924 1.91419091787233e-05 ING2 other 3.04841885086618e-09 0.279663293101148 0.234037220015176 4.31515260377919 -4.34052356187924 6.12282728853068e-09 82.7971146699101 24.7632994245838 3.34354131290409 0.000926289823507163 -162.5559835124 46.204288888836 -3.51820117616131 0.0004980045336473 CDKN2AIP other 7.17840271307336e-05 1 1 3.34354131290409 -3.51820117616131 2.04559519778458e-06 66.8277180344069 14.0060527220718 4.77134560039851 2.79350556059707e-06 2.58445054159129 31.3323419881701 0.0824850738118165 0.934312882021143 SNRNP48 essential 0.020633918760053 1 0.0324772956475015 4.77134560039851 0.0824850738118165 5.67575252626314e-10 120.757678788248 21.2563187607997 5.6810250235307 3.06219638044529e-08 -149.690398834969 79.7342988164233 -1.87736521242394 0.0613979174054151 TMEM223 other 6.92895868406204e-06 1 0.000389082672099379 5.6810250235307 -1.87736521242394 5.61772623011261e-11 338.162737295359 120.491126433856 2.80653644217522 0.00536968262880684 -1167.53418035376 282.123965963127 -4.13837291833035 4.66837115738346e-05 SLC20A2 other 7.0890087297791e-07 0.674112795126171 1 2.80653644217522 -4.13837291833035 1.86104517666106e-05 85.8890406365631 21.388100474761 4.01573953413564 7.3890456374729e-05 -114.192854964978 51.5630329174436 -2.21462641943133 0.0274899280020795 TMUB2 other 0.173337747754212 1 0.776662586954777 4.01573953413564 -2.21462641943133 0.0259736417976776 192.054682747198 294.360083322089 0.652448119254852 0.514580532823526 -1953.83444988152 759.474675026911 -2.57261303652066 0.010543885222266 STAT3 other 1 1 1 0.652448119254852 -2.57261303652066 2.63160881250161e-17 58.3905619655727 7.00372014977063 8.33707811233505 2.28477347724623e-15 -62.8187368656884 31.840507795182 -1.9729188136627 0.0493651895482867 ZSWIM1 other 3.72346330880852e-13 1 3.30172615196852e-11 8.33707811233505 -1.9729188136627 3.10904230373753e-07 557.605793802085 157.956056160539 3.53013241376046 0.000484653191257443 -685.202604788093 374.587490674204 -1.82921913263795 0.0684189296401417 ADAM9 other 0.00333662420037112 1 1 3.53013241376046 -1.82921913263795 0.0103985579278161 13.3949319609212 4.65164943763925 2.87960908071337 0.00425348205951561 38.7435813561293 31.2633728856881 1.23926428212951 0.216167263715328 GDNF other 1 1 1 2.87960908071337 1.23926428212951 0.92113014584141 -0.883594900686836 9.85580312743765 -0.0896522474385662 0.92862000228242 8.70800902787146 22.8036622895779 0.381868882168603 0.702813673735906 AXIN2 ts 1 1 1 -0.0896522474385662 0.381868882168603 0.000707798442519586 534.281609744292 144.980900047876 3.68518618361356 0.000268569064802066 -198.732778435717 362.936879657461 -0.54756843290018 0.584372373997513 NDUFS5 essential 1 1 1 3.68518618361356 -0.54756843290018 0.195167707258806 3.52844561471751 2.41986846129099 1.45811463356777 0.145792751827603 -4.8992969100089 7.51042854645213 -0.652332537312174 0.514656446280172 ZNF30 other 1 1 1 1.45811463356777 -0.652332537312174 0.00173633301155931 113.056669807399 31.3916727598159 3.60148599510508 0.000367999074017859 63.7932027721746 182.365518086194 0.349809566203316 0.726717627935493 FAM84B other 1 1 1 3.60148599510508 0.349809566203316 0.932633911111146 -5.51253480716878 14.9540851368572 -0.368630695674061 0.712661292939121 -8.0894904569842 63.2806989926188 -0.127835036365951 0.898364603334039 LDLRAD4 other 1 1 1 -0.368630695674061 -0.127835036365951 0.855241450111904 0.662050547160009 5.79805996051938 0.114184839699502 0.909162877427713 -4.76602976087081 10.7576004701898 -0.443038368461243 0.658037334881486 SLC16A4 other 1 1 1 0.114184839699502 -0.443038368461243 0.0129194406374453 136.255376575584 49.383223874658 2.75914300211385 0.00613212070950959 435.61900863579 315.947888439868 1.37876853928935 0.168938258975385 IL7R other 1 1 1 2.75914300211385 1.37876853928935 1.54884505817645e-06 116.561592279311 38.441788596691 3.03215840194659 0.0026278414950285 -279.260869851815 102.897061723743 -2.71398293764277 0.00701050516168338 TMEM208 other 0.0158044149736325 1 1 3.03215840194659 -2.71398293764277 0.33131139399175 6.33840947546531 4.52718918914183 1.40007612022656 0.162513609829158 -2.95871404399339 11.9278047532916 -0.248051850712671 0.804262309747641 LRP1B other 1 1 1 1.40007612022656 -0.248051850712671 0.266379982988481 38.9466895630602 70.6475077577416 0.551281861160804 0.581825184363715 -425.457254861148 315.871604075297 -1.34693099782318 0.178955548258843 WFDC12 other 1 1 1 0.551281861160804 -1.34693099782318 5.96643505139742e-08 311.274648254298 95.2834197608014 3.26682909823891 0.00120561086207788 -533.939598170343 176.786885302972 -3.02024438778529 0.00272909997789461 AHCYL1 essential 0.00066597348043698 1 1 3.26682909823891 -3.02024438778529 6.41531285467718e-27 315.391297538441 26.2113420718173 12.0326268175926 9.78414180018842e-28 -19.739063258031 168.608019845861 -0.117070725793922 0.906877910936741 DNAJC21 other 9.62296928201577e-23 1 1.48161259280253e-23 12.0326268175926 -0.117070725793922 0.393823532298445 27.3591575109719 21.1614229664092 1.29287891246258 0.196988519008399 -10.0119824844708 94.425325464062 -0.106030690762949 0.915624645999566 PKIG other 1 1 1 1.29287891246258 -0.106030690762949 0.00194066444910907 65.8538678042477 159.455525945032 0.41299207044696 0.679889878072424 -902.339610040745 289.479564732149 -3.11710987570285 0.00199255212625687 NPNT other 1 1 1 0.41299207044696 -3.11710987570285 0.676033016417212 6.30634754449614 8.47737143309128 0.743903649175901 0.457509350276855 -10.5228750213045 28.5412677069253 -0.368689825881534 0.712615560395142 FAM178B other 1 1 1 0.743903649175901 -0.368689825881534 0.162227365606101 90.2230631231749 59.1688945274553 1.52483942523736 0.128338781585221 -184.196099437559 199.207416114728 -0.92464478998852 0.355884081475913 SEMA4C other 1 1 1 1.52483942523736 -0.92464478998852 0.000508024327622128 70.7616629703123 21.49399429144 3.29215975452702 0.00111099777861617 -118.41744808892 71.1686838939794 -1.66389824301553 0.0971598072756731 CNNM3 other 1 1 1 3.29215975452702 -1.66389824301553 0.0154260382558011 -75.94502473283 103.607287468276 -0.73300852274589 0.464089840027737 428.282452869975 192.452231393071 2.22539613996595 0.0267512541853696 GSTM4 other 1 1 1 -0.73300852274589 2.22539613996595 0.00241250776405118 120.244948229942 55.6597939426383 2.16035561241682 0.0314918394929078 -173.927644557144 101.086100974078 -1.72058911048261 0.08629816296459 TET2 other 1 1 1 2.16035561241682 -1.72058911048261 0.382411538760934 -1.37041432454761 3.97448345530757 -0.344803127238469 0.730469600335555 -9.91908334030197 7.21537703920139 -1.3747144863548 0.17018483777131 CXXC4 other 1 1 1 -0.344803127238469 -1.3747144863548 0.255883936854197 20.6988360730035 18.2025666460186 1.13713832095931 0.25633389958294 -47.8989734165731 47.3644102553961 -1.01128617791913 0.312645914515027 TCTN2 other 1 1 1 1.13713832095931 -1.01128617791913 0.0250912050003609 24.461829944432 8.99716059210892 2.71883887077514 0.00691657418702632 -11.3274838108285 52.0811171287163 -0.217496943908348 0.82796280140597 SHOX2 other 1 1 1 2.71883887077514 -0.217496943908348 5.26656758036645e-06 33.6956522799079 22.8074027349204 1.47739980178964 0.140555069292753 -177.611362832179 46.1460097570543 -3.84889969397686 0.000143338567726845 PPIP5K1 other 0.0514964978008232 1 1 1.47739980178964 -3.84889969397686 1.44510166786749e-05 273.346390736634 72.6938095248031 3.76024303202005 0.000201886793143067 -169.849223946785 131.144422677038 -1.29513112704048 0.196211517833985 TSPAN5 other 0.136070773046403 1 1 3.76024303202005 -1.29513112704048 1.81033346832318e-05 66.6684863171681 15.7862673090621 4.22319507277676 3.15360331252234e-05 -57.9753029303975 38.1100354547703 -1.52126079754514 0.129194385940305 ABHD15 other 0.168849802590503 1 0.341755990978046 4.22319507277676 -1.52126079754514 2.83257313844884e-38 223.041009012827 18.9899988123035 11.7451828837567 1.22927441995529e-26 -361.916689278139 56.4392110361523 -6.41250440312342 5.27280191895245e-10 ZBTB5 other 4.32194009464524e-34 8.05631405196745e-06 1.85780243087843e-22 11.7451828837567 -6.41250440312342 0.000911590631456534 120.14714681279 57.0670453024373 2.10536827649036 0.0360407464855712 -320.062290000239 155.654719151821 -2.05623248523586 0.0405733500871133 CHTF8 essential 1 1 1 2.10536827649036 -2.05623248523586 7.66170978160099e-05 10.1318729511875 7.68352520721334 1.31864901564657 0.188229429224274 -52.4046051366715 15.5567944173867 -3.36859919406678 0.000847806472225234 ADAL other 0.668560795542503 1 1 1.31864901564657 -3.36859919406678 4.94232144122365e-05 11.7260584889564 12.2131580102984 0.960116824744977 0.337721301702557 -91.3670987237124 24.7279189212396 -3.69489640493905 0.000258662394245599 LCMT2 other 0.441546997558921 1 1 0.960116824744977 -3.69489640493905 1.13725849904391e-11 216.686451692119 36.063610266332 6.00845145818392 5.10832737056848e-09 -155.256417707148 98.3662479432223 -1.57835051100824 0.115476182993555 SNTB2 other 1.46035363862229e-07 1 6.66330222216953e-05 6.00845145818392 -1.57835051100824 0.000856345357420901 70.4486311385058 26.5396857262488 2.65446365360798 0.00834431469987338 -142.14722290959 73.9436277494718 -1.92237285667398 0.0554548046923907 ZNF507 other 1 1 1 2.65446365360798 -1.92237285667398 2.0839653290677e-17 62.982158262693 14.6677342338992 4.29392551421694 2.33026178496358e-05 -118.959441872708 27.0932511747676 -4.3907407459278 1.53697227466904e-05 STX18 other 2.95277047475602e-13 0.225197177684508 0.254860731421467 4.29392551421694 -4.3907407459278 5.74469821359913e-08 323.275417377801 71.8303162540733 4.50054286597227 9.50117990921233e-06 -84.4319426846939 132.680124223743 -0.636357127178396 0.524998579359781 NSG1 other 0.000641740237441159 1 0.106888273978639 4.50054286597227 -0.636357127178396 1.05015314178706e-08 10.7567529369184 3.44254473431068 3.12465160719902 0.00194314064326141 -17.0840391517665 6.35883686462583 -2.68666102236479 0.00759393370477491 ZBTB49 other 0.000121702247601703 1 1 3.12465160719902 -2.68666102236479 7.9513922219541e-25 391.376825597191 34.1596826469834 11.4572734659686 1.29242553899836e-25 309.389088314106 197.974049814001 1.56277597293575 0.119115762675495 GFM1 essential 1.18435987146006e-20 1 1.94949468302512e-21 11.4572734659686 1.56277597293575 0.29815184812627 25.4113323223395 19.6695277779914 1.29191369559836 0.197334070528129 -8.51133097074326 33.7037972937183 -0.252533294589022 0.800793587778314 FSTL5 other 1 1 1 1.29191369559836 -0.252533294589022 5.99331558928762e-20 195.176807226418 25.0009177977803 7.80678568703374 8.43406695509728e-14 -190.784575460356 68.1958574555398 -2.7975977218959 0.00546025161891274 DDX19A essential 8.69270493070277e-16 1 1.20143283775361e-09 7.80678568703374 -2.7975977218959 0.486702498015175 -12.3322220554079 16.5907179917026 -0.743320576094145 0.457838150873725 -69.3894182791237 69.2640285896046 -1.00181031470552 0.317199305598561 ATOH8 other 1 1 1 -0.743320576094145 -1.00181031470552 0.647855532459492 -17.8614570385829 25.7814125529066 -0.692803662403253 0.488936821966546 -81.6273576387449 116.782736551035 -0.698967673214892 0.485081523121123 SOX14 other 1 1 1 -0.692803662403253 -0.698967673214892 6.22053630154357e-16 37.1410793777743 8.82135980650603 4.21035760840201 3.33356598617944e-05 -79.1774856082176 20.813418126576 -3.80415581557545 0.000171000934692492 ANKRD49 other 8.66458501442003e-12 1 0.360891853663786 4.21035760840201 -3.80415581557545 0.651102531686083 -7.53018113094239 10.0301704047405 -0.750753060724015 0.45335819556479 -25.2781168034054 41.874619894088 -0.60366200021255 0.546500094487158 SFTPB other 1 1 1 -0.750753060724015 -0.60366200021255 0.001735261935197 152.102430386901 49.9151847867461 3.04721761597663 0.00250388970888168 -346.536433725152 208.389220276884 -1.66292878904539 0.0973150315659988 USP39 essential 1 1 1 3.04721761597663 -1.66292878904539 1.07428079353395e-16 177.051434409821 41.6418921023613 4.25176247934664 2.78677682067341e-05 -331.832336329782 77.0163246245285 -4.30859740383013 2.18888510623358e-05 TNIP2 other 1.50861251835973e-12 0.319248892744167 0.30308984701644 4.25176247934664 -4.30859740383013 0.0300711689016443 49.2678106205791 22.6262170866986 2.17746565551793 0.0301829799966727 -127.257822366271 94.4614300569436 -1.3471934766344 0.178880121315889 C2orf68 other 1 1 1 2.17746565551793 -1.3471934766344 4.95661602867449e-06 37.373482112105 7.42051461050487 5.03650812292683 7.97295029025026e-07 18.0964736428427 30.9796559973256 0.584140561289799 0.559541191691847 TMEM150A other 0.0486244032412967 1 0.00954441879245859 5.03650812292683 0.584140561289799 0.0221525774655185 94.1282223380105 65.6108289424817 1.43464461362817 0.15237418415415 -616.799713864334 273.916435318381 -2.25178059559445 0.0250204061604146 RNF181 other 1 1 1 1.43464461362817 -2.25178059559445 0.0868103566174772 12.9209196965547 31.5068379546812 0.410098903455175 0.682010411396068 -281.506919360964 131.536834388511 -2.14013755667479 0.0331066172928478 VAMP5 other 1 1 1 0.410098903455175 -2.14013755667479 1.66943968775245e-24 110.759341251598 10.2202334076621 10.8372614238499 1.61070166560028e-23 -24.6168679737678 28.7551498080909 -0.856085540783422 0.392591042254064 LRRC28 other 2.48262375965667e-20 1 2.41862962106537e-19 10.8372614238499 -0.856085540783422 0.153647090590677 -252.85907818392 132.215429549373 -1.91247783292566 0.0567159439330297 -269.925410436887 551.981734417681 -0.489011490066148 0.625171720643899 MAT2A essential 1 1 1 -1.91247783292566 -0.489011490066148 0.0100915557165588 140.007512831563 61.622686759522 2.27201247128241 0.0237490947164089 -118.629796094279 123.226784192777 -0.962694895199842 0.336427555523004 PLA2G4F other 1 1 1 2.27201247128241 -0.962694895199842 0.397836651653494 -4.14352074468563 17.9622977945814 -0.230678769056795 0.817711776796245 -35.0813596814993 26.4750959502665 -1.32507016206475 0.186093241473587 ZNF608 other 1 1 1 -0.230678769056795 -1.32507016206475 8.14452732281638e-09 51.6249806365646 8.32095448922127 6.20421379583774 1.70475755207434e-09 -11.3653445000761 36.9976633849066 -0.30719087261907 0.758898532894762 SLC35G2 other 9.49570440567161e-05 1 2.25385995959748e-05 6.20421379583774 -0.30719087261907 0.00208724564383533 -146.541171265442 56.4875478428543 -2.59422079487523 0.00991664950623598 -324.670416101916 97.43319974747 -3.33223600316325 0.000962421931240234 INPP5D other 1 1 1 -2.59422079487523 -3.33223600316325 9.27404993187432e-23 368.836994164315 59.5158851998599 6.19728653830361 1.7672655222239e-09 -450.71451718872 109.770795558803 -4.10596019546273 5.11696718717682e-05 LETM1 essential 1.36931347244124e-18 0.737969007734641 2.33632502037999e-05 6.19728653830361 -4.10596019546273 1.35296698501032e-08 139.767721508891 43.4715077599598 3.2151569777763 0.00143767384798975 -215.65994954563 80.2570536442576 -2.68711520985496 0.00758624262719023 TMEM129 other 0.00015601062304154 1 1 3.2151569777763 -2.68711520985496 0.0235995712404051 161.368906249999 60.4691624176248 2.66861487406622 0.00800461385387328 36.5025328947364 89.1124498786051 0.409623267505973 0.682356388223503 PPIC other 1 1 1 2.66861487406622 0.409623267505973 3.01467536354849e-06 -5.25541666666654 20.0881294151022 -0.261618021174014 0.793784258110593 -143.189561403508 29.6035591380454 -4.83690358770026 2.05291749352681e-06 CEP120 other 0.0300744014267597 0.0306295290034199 1 -0.261618021174014 -4.83690358770026 0.349625162693382 -18.779944697877 15.2589318013342 -1.2307509426207 0.219325579912632 18.3149722073562 41.2509491197181 0.443989110509982 0.657352422829203 STXBP6 other 1 1 1 -1.2307509426207 0.443989110509982 4.01142729589753e-06 75.9286749862997 43.0253590735356 1.76474238963418 0.0785609601935629 -258.077395617277 74.5772890607952 -3.46053602735402 0.000612245113375455 MFF other 0.0396048216923963 1 1 1.76474238963418 -3.46053602735402 0.110595187627424 -258.131704404333 145.580654598929 -1.77311817367135 0.0772005666877186 -488.741117170454 353.614181363491 -1.38213098605359 0.167936251324656 LGALS9 other 1 1 1 -1.77311817367135 -1.38213098605359 5.93340168273524e-05 226.896723232336 89.8706663545117 2.52470280277325 0.0120626760895675 -422.745833523202 179.407586201919 -2.356343131708 0.0190583760996435 JMJD7-PLA2G4B other 0.524572042770623 1 1 2.52470280277325 -2.356343131708 0.0422147038357637 9.7745266132255 6.87243992650974 1.42227894572367 0.155928492579508 32.0488172466097 12.6778167061784 2.52794451831687 0.0119586639147413 CPLX1 other 1 1 1 1.42227894572367 2.52794451831687 0.000181573381903751 77.8911095648084 37.0564723460112 2.1019569493153 0.0363432531735083 -203.931805430986 82.2119053433848 -2.48056293768157 0.0136345265074321 PXDC1 other 1 1 1 2.1019569493153 -2.48056293768157 0.50973759696174 0.621260299472693 3.05044515386482 0.203662176546782 0.838747358905495 -8.0213322381839 7.44530126380037 -1.07736839034093 0.282129766184542 SIGLEC7 other 1 1 1 0.203662176546782 -1.07736839034093 4.72233060625501e-07 36.7080726164992 8.30817257163232 4.41830887598993 1.36465281673294e-05 -54.8127958793022 25.2549232326517 -2.17038061744871 0.030715443075301 E2F6 other 0.00500142034508468 1 0.151708453636201 4.41830887598993 -2.17038061744871 6.19894055189616e-06 369.41453073868 111.50404770215 3.31301453491142 0.00102868021687521 -488.465121044291 217.01188361518 -2.25086807647119 0.0250723719706527 FEM1B other 0.0602661000455345 1 1 3.31301453491142 -2.25086807647119 2.14391622809668e-10 62.1519532099012 18.2302603792871 3.40927402663525 0.000738106488869198 -138.277165551347 38.1210998102402 -3.62731312159578 0.000335089897968662 COMMD8 other 2.65909929770831e-06 1 1 3.40927402663525 -3.62731312159578 0.00143776424774313 188.955228049288 157.04993969364 1.20315377654959 0.229814602632453 -649.356963596924 289.715206017598 -2.24136307004017 0.0256943324258697 ATP5I other 1 1 1 1.20315377654959 -2.24136307004017 9.70970424264392e-05 190.111993839745 76.1076508584318 2.49793538094315 0.0130201102015794 -568.234030658804 201.566048625313 -2.81909594663475 0.00513198515078172 UQCRFS1 essential 0.837947476140171 1 1 2.49793538094315 -2.81909594663475 0.724143190552248 7.91603296990054 10.8159881535174 0.731882548089351 0.464780976713117 2.38094434749275 19.9526102480069 0.119329968254684 0.905089528553108 MFSD7 other 1 1 1 0.731882548089351 0.119329968254684 0.48762623826858 -7.25203770888678 6.46757750773439 -1.12129119445639 0.263004665250598 -9.93851925331403 11.2104676800729 -0.88653921825047 0.375992793937115 COL4A3 other 1 1 1 -1.12129119445639 -0.88653921825047 8.11878269556402e-05 217.466382442017 67.4566610664747 3.22379404796979 0.00139550799795586 -217.948253491129 132.205955699077 -1.64855094718437 0.100221049536973 MAP2K1 other 0.705765779725381 1 1 3.22379404796979 -1.64855094718437 0.678493888019665 333.105074950537 459.135818636111 0.725504439928134 0.468674513483151 -379.02411395066 1114.94327337327 -0.339949235985718 0.734118483459425 KLK7 other 1 1 1 0.725504439928134 -0.339949235985718 0.00274813708980669 388.135542308478 230.390185257875 1.6846878345709 0.0930237977111386 -808.002474883723 352.937782475044 -2.28936236074656 0.0227091716959435 HNRNPH1 essential 1 1 1 1.6846878345709 -2.28936236074656 3.95715205528067e-09 588.705161733386 123.602466724731 4.76289169086296 2.89772192966959e-06 -361.54945982505 214.244275656201 -1.68755715277654 0.0924706593954611 IRS1 other 4.6793323053694e-05 1 0.033651244769253 4.76289169086296 -1.68755715277654 3.04984383020698e-10 72.3909849925643 12.5790101453999 5.75490314069248 2.09347650142401e-08 -68.9797504926148 30.4887057540292 -2.26246896306836 0.024364843419303 UPF3A other 3.76167738017728e-06 1 0.000267755644532131 5.75490314069248 -2.26246896306836 0.165112589007695 71.3118263407698 38.7477845752349 1.84041041629894 0.0666338283863726 -16.9629091966072 73.9480381812549 -0.229389576976055 0.818712681919632 ROR2 other 1 1 1 1.84041041629894 -0.229389576976055 2.00484788718996e-14 75.4891780207126 9.36262041507728 8.06282586220703 1.50486074251331e-14 -25.0851235890358 36.8595551853041 -0.680559585239847 0.496642316444434 HSPBAP1 other 2.72859797446554e-10 1 2.15902370728385e-10 8.06282586220703 -0.680559585239847 0.0190294383059087 27.5418869789829 42.764773936735 0.644032095661902 0.5200174004712 -192.734312046754 85.3817947595856 -2.25732326884727 0.0246638670242294 CHST14 other 1 1 1 0.644032095661902 -2.25732326884727 0.483275932599077 -139.370168898076 245.85672561501 -0.566875559533469 0.571197378068444 -636.039495942335 531.29020706155 -1.19716021016109 0.232132984431018 PARM1 other 1 1 1 -0.566875559533469 -1.19716021016109 0.0015596110092975 83.4273229765893 38.6820041962162 2.1567476843599 0.0317698112116759 -148.918291424332 75.6940981841672 -1.96736991386049 0.0500040583550035 CSNK1G1 other 1 1 1 2.1567476843599 -1.96736991386049 0.738109343954007 -2.84428052591571 6.93198693265692 -0.410312447722048 0.681860193768459 -23.0033118424881 32.0886765133471 -0.716866955635269 0.473995941275167 FAM110B other 1 1 1 -0.410312447722048 -0.716866955635269 1.42099250777041e-06 262.772718790819 132.659933743147 1.98079941227465 0.048469696948678 -916.087669257113 254.134072365798 -3.60474162605991 0.000362259817532381 AFAP1L2 other 0.014550963279569 1 1 1.98079941227465 -3.60474162605991 4.30832267443924e-07 62.1338533364236 13.8059679078686 4.50050686420984 9.50269321882714e-06 -31.9538066023679 21.450235688243 -1.48967158528155 0.137295535932648 ZNF354A other 0.00457630034478936 1 0.106888728001382 4.50050686420984 -1.48967158528155 2.22991041403771e-11 235.33374161461 36.0795939217403 6.52262722593467 3.1259694663453e-10 -361.76588970218 181.935124646632 -1.98843346167943 0.0477167179317222 UBE2V2 other 2.84380475102229e-07 1 4.20567932002097e-06 6.52262722593467 -1.98843346167943 8.23731210870267e-09 131.092169421548 20.8791382702774 6.27861972676167 1.11188577659733e-09 21.0880058765568 40.8810534351444 0.515838123154331 0.606323689888367 ZBTB43 other 9.6022347251147e-05 1 1.4783633285638e-05 6.27861972676167 0.515838123154331 0.00559317030322835 37.0021767145087 15.4870336185239 2.38923590055689 0.0174622556172504 -59.6514948988446 36.2485624627534 -1.6456237391521 0.100823063435344 CPT1C other 1 1 1 2.38923590055689 -1.6456237391521 0.330238416327444 188.279601591885 153.909441688052 1.22331417440585 0.222116776483808 412.273959068664 368.758586707199 1.11800504159112 0.264408726773682 PCSK9 other 1 1 1 1.22331417440585 1.11800504159112 3.87215042829819e-11 376.450519272513 73.7460468588081 5.10468744166387 5.7149939547718e-07 -883.081561704121 260.924824804389 -3.38442906828108 0.000802577033968404 XPO6 other 4.9098867430821e-07 1 0.00688999671187288 5.10468744166387 -3.38442906828108 1.66546703178933e-07 303.395815950821 56.4645114469817 5.37321245107558 1.50094302542643e-07 -115.677343963705 162.790041256179 -0.710592263943625 0.47785939606316 MN1 other 0.00181502597124402 1 0.00185666652245249 5.37321245107558 -0.710592263943625 0.0827026858876171 55.7133803929139 62.3494405184165 0.89356664518036 0.372227427442296 -375.696900582617 221.173364363907 -1.69865345975596 0.0903595214878306 NSMCE1 essential 1 1 1 0.89356664518036 -1.69865345975596 0.0011184274893377 24.4450639133061 6.62231844707305 3.69131507472437 0.000262439481445808 3.76131367544016 27.9790539924815 0.134433196935496 0.893145075835574 CCDC126 other 1 1 1 3.69131507472437 0.134433196935496 0.280949585711188 -111.825735792976 89.248450289615 -1.25297117686746 0.211136738268834 146.174845733854 217.156167729068 0.673132369494692 0.501351968833336 RAB3B other 1 1 1 -1.25297117686746 0.673132369494692 1.87886051192471e-07 240.462277237846 56.8962302708 4.22633056871002 3.11749909957152e-05 -484.840252350938 195.850332924173 -2.47556511705626 0.0138297793428487 CD2BP2 essential 0.00204213349041097 1 0.338061602357535 4.22633056871002 -2.47556511705626 2.73088065802144e-10 86.6243773606506 43.5760381464 1.98789015810991 0.047675710092158 -364.636032695537 66.2156576276229 -5.50679470324287 7.5126554186577e-08 RGS14 other 3.37372996491969e-06 0.00113651451173454 1 1.98789015810991 -5.50679470324287 6.42229183291903e-08 210.210782945587 46.587407983781 4.51218026593731 9.08056048229924e-06 -381.563669423589 160.364919086396 -2.37934625351586 0.0179405551621231 TBC1D10B other 0.000715635978942168 1 0.102283433272619 4.51218026593731 -2.37934625351586 3.83618573665031e-11 724.525184386127 151.674332844484 4.77684767619186 2.7162621255359e-06 -790.399501789828 230.475649502299 -3.42942737550217 0.000684075833705338 LMAN2 other 4.86466713264626e-07 1 0.0316227236654889 4.77684767619186 -3.42942737550217 1.57677691149962e-07 108.746887913567 39.654578762719 2.74235387959297 0.00644343703297529 -229.153865816841 60.2568320208048 -3.80295243098279 0.000171223285911595 RAB24 other 0.00172089432121069 1 1 2.74235387959297 -3.80295243098279 1.51123619099759e-15 497.317810322861 92.8312578276822 5.35722365462295 1.61846968466306e-07 -655.364481996632 141.061075006591 -4.64596262268674 4.95212888422243e-06 PRELID1 essential 2.09505649381306e-11 0.073425214966366 0.00199816267268502 5.35722365462295 -4.64596262268674 6.17325045991679e-15 188.265596923054 22.3909239578776 8.40812095459857 1.42039340369086e-15 -138.176811644072 78.4917620613906 -1.76039890066426 0.079301472828122 THBS3 other 8.4795768317417e-11 1 2.05616149118289e-11 8.40812095459857 -1.76039890066426 2.78067295343043e-06 181.567394229961 35.1802442874838 5.16106121225991 4.33376357932426e-07 -17.4216502649513 123.324940456656 -0.141266236986949 0.887749068041861 SLC50A1 other 0.027798387515444 1 0.0052538215872148 5.16106121225991 -0.141266236986949 2.84400832747368e-07 777.938787955257 138.798250559805 5.60481695423143 4.5238276238636e-08 103.796934140797 486.55961129485 0.213328298796869 0.831207602729484 EFNA1 other 0.00305929975786343 1 0.000570907046131586 5.60481695423143 0.213328298796869 0.265673332323267 -757.597826351837 571.079766179253 -1.32660596858555 0.18559393216519 -1590.16316605436 1170.97810853627 -1.35797856036956 0.175436251487058 CXCL10 other 1 1 1 -1.32660596858555 -1.35797856036956 0.0136270758347408 24.3492445143159 9.23912855983832 2.63544817637455 0.00881182019857253 -4.81950626477575 13.425931854707 -0.358969963271941 0.719854292084628 SH3TC2 other 1 1 1 2.63544817637455 -0.358969963271941 0.362573699166889 -266.925670492971 203.949956795972 -1.30878022572959 0.191556812650401 -415.924564318821 418.191903808477 -0.994578231981522 0.320700007051648 CXCL11 other 1 1 1 -1.30878022572959 -0.994578231981522 8.6503456748436e-23 298.016796729461 27.4070366461676 10.8737329240275 1.41477816747177e-23 202.847271913753 163.34675288611 1.24182004435181 0.215232683457058 NMD3 essential 1.27739654580415e-18 1 2.12457237409236e-19 10.8737329240275 1.24182004435181 6.2365068517174e-05 221.065257933756 57.2884088398239 3.85881302013197 0.000137817841855934 -67.9318696009458 83.2492229290431 -0.816006050396976 0.415103665901051 ADRB2 other 0.549872809115923 1 1 3.85881302013197 -0.816006050396976 0.00194072663359983 40.676209349607 11.9149946561846 3.41386719200025 0.000724802079266573 70.2659321783028 69.8832152205936 1.00547652188728 0.315444117195898 B3GALNT1 other 1 1 1 3.41386719200025 1.00547652188728 7.91565318210965e-09 173.333321185103 32.4359445385164 5.34386538302519 1.73191581476884e-07 -63.2812456598804 49.3896867099955 -1.28126436661672 0.201028518968194 GPRIN1 other 9.23123474097627e-05 1 0.00213562539119145 5.34386538302519 -1.28126436661672 1.58279928158214e-20 917.852218475885 89.3664135412788 10.2706618975139 1.58533737136304e-21 504.95017171379 150.989915704375 3.34426421366071 0.000924940350016507 HSPB3 other 2.30550543355255e-16 1 2.36881110029066e-17 10.2706618975139 3.34426421366071 0.000185308056091379 6.37988577566391 1.58448383239628 4.02647578045359 7.09963410124519e-05 -10.4740989108356 9.11061831174962 -1.14965840433986 0.251156702846884 KCNAB1 other 1 1 0.747236489156056 4.02647578045359 -1.14965840433986 4.27542908885252e-05 39.0553926946568 19.5839985850033 1.99425017956057 0.046980956815466 -110.062386455535 36.9999353855186 -2.97466428816015 0.00315835021556965 MRPL1 other 0.38440382937873 1 1 1.99425017956057 -2.97466428816015 0.465197739433967 8.2882410318454 13.0663866592587 0.634317753483318 0.526326667060074 -50.3757268506697 46.2563910463304 -1.08905441412871 0.276949366209949 SHE other 1 1 1 0.634317753483318 -1.08905441412871 2.05830627671898e-11 379.752425586809 93.5615050497861 4.05885332204452 6.20856671978577e-05 -574.575873887453 187.479518796854 -3.06473943167116 0.00236456420442716 PGM2 other 2.62783962348712e-07 1 0.656928444620532 4.05885332204452 -3.06473943167116 0.8007533347926 0.638520068936968 2.52294314807584 0.253085397276568 0.800365751799386 -4.23107028165279 7.65297262976229 -0.55286625032451 0.580743424299839 C22orf15 other 1 1 1 0.253085397276568 -0.55286625032451 0.936476906317485 -0.885549921538186 2.64522756373298 -0.33477268030902 0.738015896971581 -1.30002542588355 5.16706972111095 -0.251598197053946 0.801513151344196 KIAA1024 other 1 1 1 -0.33477268030902 -0.251598197053946 0.643182903724262 -122.883601354707 144.421593406325 -0.85086723152942 0.395479337977828 -274.203191422795 440.100591395042 -0.623046632483766 0.533697657674679 GP2 other 1 1 1 -0.85086723152942 -0.623046632483766 6.26597710745973e-16 221.577281991705 25.3168632809346 8.75216173239631 1.28086589618337e-16 207.104070026769 144.432657368912 1.4339144193531 0.152585447194236 SLC33A1 other 8.72725291526992e-12 1 1.86660587050802e-12 8.75216173239631 1.4339144193531 1.26907636032179e-06 75.2521114761553 19.5519711522144 3.84882480085044 0.000143298213716975 -76.0425561921043 38.0202678972425 -2.00005314001534 0.0463393419181806 SNUPN essential 0.0130448359077476 1 1 3.84882480085044 -2.00005314001534 0.252093787698981 -11.8197938717947 8.44889706185026 -1.398974775674 0.162792075903074 -23.1433090158004 20.5541031070922 -1.12597026954754 0.26102447161587 CRADD other 1 1 1 -1.398974775674 -1.12597026954754 1.00863555080862e-05 278.085585705123 69.8143066367993 3.98321775437563 8.42185607323385e-05 -154.168650346094 134.24976746794 -1.14837182405482 0.251672809341144 SIN3A essential 0.0962742633246825 1 0.880083959652937 3.98321775437563 -1.14837182405482 1.85231454743861e-12 89.2046516231196 12.3491897686876 7.22352261921714 4.12257631697137e-12 -33.3407084272286 49.2844001953491 -0.676496179218488 0.499241746108203 ARL13B other 2.42430927968765e-08 1 5.73697720269736e-08 7.22352261921714 -0.676496179218488 1.52622588942835e-10 433.884914081164 62.2895810239324 6.96560976890276 1.87609059260044e-11 283.068894553774 318.98771880798 0.887397469757047 0.3755335011384 PTK2 other 1.89816713868203e-06 1 2.58225109165525e-07 6.96560976890276 0.887397469757047 1.04982532360899e-06 28.0663276016437 5.50891156600764 5.09471376792923 6.00019292293652e-07 -23.1731892258168 26.3535330626457 -0.879320020231485 0.379891754581568 RSPH10B2 other 0.0108530941954698 1 0.00722603233709245 5.09471376792923 -0.879320020231485 0.0188961493608226 86.2621078687424 66.6636201937145 1.29399074964842 0.196601736384724 -286.231911807271 133.683143208955 -2.14112194654095 0.0330193323176049 PTAFR other 1 1 1 1.29399074964842 -2.14112194654095 0.000565371254389288 103.131908416079 37.5271402920772 2.74819524252031 0.00633239152501944 -113.148655063874 72.1630006892107 -1.56795939724263 0.117878893735898 PTPN9 other 1 1 1 2.74819524252031 -1.56795939724263 0.0829486313736792 -20.7856315493145 9.41053642432689 -2.20876160636096 0.0279017978899991 -21.4306237075689 26.3401145800656 -0.813611635683157 0.416474337232324 RNASE6 other 1 1 1 -2.20876160636096 -0.813611635683157 0.0443567425881282 37.7445988935993 15.1290520840261 2.49484228648083 0.0131050772729426 -16.486040897831 54.3318632483314 -0.303432275504325 0.761757633952383 NPR1 other 1 1 1 2.49484228648083 -0.303432275504325 0.421373779839615 2.34331051586302 2.11893209959678 1.10589221632394 0.269606491947268 8.88340191056114 10.9321446347218 0.812594619572298 0.417056524240587 KCNK9 other 1 1 1 1.10589221632394 0.812594619572298 0.495186850605105 -230.525954409898 508.053911083887 -0.453743095724019 0.65032324267513 -1305.59677429743 1100.7968699207 -1.18604695377767 0.236489174530856 CXCL8 other 1 1 1 -0.453743095724019 -1.18604695377767 0.0701141147339071 103.623576629975 45.760561398812 2.26447345623398 0.0242222543669745 -9.70852497883133 130.661672007761 -0.074302776243784 0.940816480927613 SCN9A other 1 1 1 2.26447345623398 -0.074302776243784 0.00161130791480756 -57.8831708029261 20.3190464132409 -2.8487149261693 0.00467568223823125 -135.920025163228 44.0251363162438 -3.08732775264748 0.00219746669590874 RASSF6 other 1 1 1 -2.8487149261693 -3.08732775264748 0.0758913377766811 85.4811712935735 59.7391126161159 1.43090795209625 0.153438537047096 -505.872302848546 312.860249966173 -1.616927375412 0.106885476974708 COL22A1 other 1 1 1 1.43090795209625 -1.616927375412 0.212319558839412 116.317372175111 72.3856123937958 1.60691287023055 0.109059724879492 -216.705530750782 371.197152202266 -0.583801706088247 0.559765003141939 SDC2 other 1 1 1 1.60691287023055 -0.583801706088247 0.684041037558329 -24.8311448578924 38.0612481721914 -0.652399646631522 0.514611753322131 -54.6582076384171 74.6600012021622 -0.732094920416827 0.464646466106466 CD52 other 1 1 1 -0.652399646631522 -0.732094920416827 0.451757378145369 -2912.83839504016 2789.5790179141 -1.0441856553747 0.297187657500896 7440.96342298289 10186.6492505079 0.730462317882584 0.465642082561497 SPRR1B other 1 1 1 -1.0441856553747 0.730462317882584 0.96454091226775 231.076234896766 1010.76956130683 0.228614160677737 0.819314844036245 559.309744476386 4068.56015975699 0.13747117469434 0.890744831896328 SPRR1A other 1 1 1 0.228614160677737 0.13747117469434 1.69563386858192e-22 205.793479801235 27.9520650182607 7.36237124759092 1.97622788004179e-12 -196.975691539696 66.2873849148955 -2.97154114304837 0.00321757819166326 TM2D2 other 2.49970344906347e-18 1 2.76355706745044e-08 7.36237124759092 -2.97154114304837 1.81994150072676e-14 111.161770689048 37.5671421391666 2.9590158941889 0.00334712666870604 -454.666490667472 89.0892178987381 -5.10349626353507 6.12570108996779e-07 PLEKHA2 other 2.47930630644006e-10 0.00920141560724062 1 2.9590158941889 -5.10349626353507 0.0002177529556787 893.308503053679 217.442852940158 4.10824495252335 5.0728337193411e-05 200.41828981553 423.624209361092 0.47310395720254 0.636462574871745 CLIC4 other 1 1 0.540865531156148 4.10824495252335 0.47310395720254 0.730371201436529 9.979192962639 19.5970358435018 0.509219508620126 0.610956023748909 -27.969953669415 54.7416016293055 -0.510945110061258 0.609748543459796 SLC38A11 other 1 1 1 0.509219508620126 -0.510945110061258 0.374554789727766 -17.1515275267049 13.651595932925 -1.25637527003995 0.20991088294028 -28.6389661051766 31.6956242611329 -0.903562140604229 0.366918086774639 GPR183 other 1 1 1 -1.25637527003995 -0.903562140604229 0.354624977511795 -181.933182617432 171.496734060243 -1.06085508633374 0.28955828244747 682.548934361292 690.489008309484 0.988500796026237 0.323656618521202 CRCT1 other 1 1 1 -1.06085508633374 0.988500796026237 0.0139152785291801 198.270667890024 68.5415343922279 2.89270833587447 0.00408113576493918 27.6532888284241 157.760907020794 0.17528606643203 0.860965719536486 CCDC8 other 1 1 1 2.89270833587447 0.17528606643203 8.69146716631836e-10 17.8833606465836 9.41886225518002 1.89867524994841 0.0585150873052565 -99.5344089967334 20.3441726338556 -4.89252675879745 1.58666102586943e-06 METTL15 other 1.0538403939161e-05 0.0237094757095669 1 1.89867524994841 -4.89252675879745 0.00654081843205621 40.6997702843072 41.5987087612299 0.978390231242934 0.328629782988834 -201.205546924693 88.3721684817486 -2.27679766584259 0.0234666005777548 MUC15 other 1 1 1 0.978390231242934 -2.27679766584259 0.841633634524254 18.8684928858547 36.4605715685281 0.517504034471624 0.605167570125385 -18.1336910152103 94.6534533496395 -0.191579814296119 0.848194786974095 ZEB2 other 1 1 1 0.517504034471624 -0.191579814296119 4.9570115649013e-16 1621.65763436936 182.672164916601 8.87742056984831 4.98288940251943e-17 -139.95859943637 785.451908440766 -0.178188629924152 0.858687588741333 PCBP1 essential 6.91403973072433e-12 1 7.28000141708088e-13 8.87742056984831 -0.178188629924152 3.25508909216825e-08 285.4687099386 183.338260911155 1.55706020401785 0.120444610209045 -1322.65515990824 276.277640118672 -4.78741297826385 2.58622711888863e-06 HINT1 other 0.000368606288797132 0.0385270253900839 1 1.55706020401785 -4.78741297826385 0.00337535207777732 11.8217577993618 8.9202128961153 1.32527753956524 0.186024552449136 -31.6232773295771 13.320397104979 -2.37404914285602 0.018183946885552 DTWD2 other 1 1 1 1.32527753956524 -2.37404914285602 0.017359767707993 60.8120589047035 82.8162275084331 0.734301244264128 0.46330455203227 -462.178571236555 174.248816831479 -2.65240579328318 0.00839166704338328 CLIC3 other 1 1 1 0.734301244264128 -2.65240579328318 0.0334031996011295 32.6478392372345 32.9188770014552 0.991766494215197 0.322067855973299 -245.460621676329 119.198616857995 -2.05925729799997 0.0402860536499588 INO80E other 1 1 1 0.991766494215197 -2.05925729799997 0.000108813770457592 812.039645942186 206.778890689365 3.927091606087 0.000105668447807176 -155.017727473499 407.865715013846 -0.380070503028765 0.704149216421345 BNC1 other 0.933622150526139 1 1 3.927091606087 -0.380070503028765 0.0384885714623027 -6.16457400976917 6.50694241120912 -0.947384135312129 0.344157933685375 -36.848330142295 14.4141358947676 -2.55640229919512 0.0110374871856035 DFFB other 1 1 1 -0.947384135312129 -2.55640229919512 0.212855546136854 23.0347704741693 13.6595561785345 1.686348383 0.0927064127440973 -30.1305201034974 58.7237496437202 -0.513089172375755 0.608244081543184 NFU1 other 1 1 1 1.686348383 -0.513089172375755 0.048603631696339 491.700344415099 202.519791073826 2.42791256009076 0.0157388056837274 -396.796402133525 873.337223838186 -0.454345001338274 0.649889523929788 ANTXR1 other 1 1 1 2.42791256009076 -0.454345001338274 0.106575477369878 25.8431240332221 31.1303392069947 0.830158767669817 0.407067921059957 -183.379777177354 101.647806672842 -1.80407018291669 0.0721605399890071 CKAP2L other 1 1 1 0.830158767669817 -1.80407018291669 1.08653358613784e-07 92.1034386778501 19.4322942238148 4.73970997027076 3.24538133245761e-06 -58.8368311159777 38.3296696850078 -1.53502056238672 0.125782546727856 C15orf40 other 0.00119649078505499 1 0.0376009881178539 4.73970997027076 -1.53502056238672 0.000143241185509498 36.4627897516093 12.1324352027239 3.00539744431711 0.00286540941249143 -43.4894622441686 23.9308971158566 -1.81729343591355 0.0701222286696571 FAM103A1 other 1 1 1 3.00539744431711 -1.81729343591355 0.000294767195387465 34.8510041130827 8.53368249054733 4.08393494270344 5.60058229965161e-05 16.9042614346479 27.7630800125289 0.608875579619386 0.543038901652507 RGPD8 other 1 1 0.594277787816032 4.08393494270344 0.608875579619386 2.56529185668109e-07 65.2167735224438 12.3432320150183 5.28360590184912 2.36898821927071e-07 -38.9457196054314 40.5303782789574 -0.960901952046455 0.337338470602515 HIC2 other 0.00276743685498756 1 0.00290556405093553 5.28360590184912 -0.960901952046455 0.000123528887624148 342.82401721442 98.2101053497692 3.49072038965311 0.000549342199285021 -263.217990800132 189.734181240211 -1.38729874121568 0.166316098951364 LUZP1 other 1 1 1 3.49072038965311 -1.38729874121568 0.848873868868131 5.78842290031799 26.3005103973859 0.220087854298573 0.825944399082241 -27.431718339238 58.9087996078162 -0.465664188064668 0.641775658069717 HEXDC other 1 1 1 0.220087854298573 -0.465664188064668 0.00938119765252855 97.0879842445896 36.4131331383516 2.66629031552171 0.00805894201339404 -134.895647467683 121.134963489991 -1.11359795373058 0.266287465056263 BUB1 other 1 1 1 2.66629031552171 -1.11359795373058 8.39109382895019e-07 152.200715303734 40.279615367508 3.77860398901695 0.000188162301555868 -375.553111711548 143.550538898899 -2.61617347167221 0.00931514466338718 SPNS1 other 0.00873512867593715 1 1 3.77860398901695 -2.61617347167221 0.112855047251687 65.9941819877762 31.7282166603362 2.07998396803298 0.0383275968662698 51.2078618436103 71.0517628265203 0.720712052826039 0.471616160250581 LRRC45 other 1 1 1 2.07998396803298 0.720712052826039 0.0325705105977035 24.0303448737798 10.1666471510393 2.36364501657002 0.0186933866678781 -3.98815212882986 19.7849836227744 -0.201574699523082 0.84037730120664 CHRNA5 other 1 1 1 2.36364501657002 -0.201574699523082 0.0476089751772915 1.58210520240111 2.75480683845691 0.574307127568813 0.566163467307426 -13.7468857083836 7.29031908236881 -1.88563567013543 0.0602497050078508 MT1B other 1 1 1 0.574307127568813 -1.88563567013543 0.0201472391253384 129.389049311417 46.421555741831 2.78726223720294 0.00563516901884044 27.7362283429586 103.955838549538 0.266807797714426 0.789790083101561 CENPX other 1 1 1 2.78726223720294 0.266807797714426 4.14787162168031e-14 678.508945112304 83.3477168456923 8.14070223865252 9.15946993155582e-15 -54.0425039133551 174.162612504329 -0.310299111481299 0.756538058563198 AGPAT2 other 5.60833721967395e-10 1 1.31649061326252e-10 8.14070223865252 -0.310299111481299 0.00787448770401295 121.852398195855 38.8742162320778 3.1345300306095 0.00188181811081422 52.1375051472141 87.0544229244804 0.598907021558725 0.549661282703396 ASPSCR1 other 1 1 1 3.1345300306095 0.598907021558725 4.90126853484364e-06 1338.28087073888 310.097765775271 4.3156740178152 2.12738299685995e-05 -1088.29369412782 694.428972884632 -1.56717783477134 0.118067643801451 FASN other 0.048086345595351 1 0.233373914755537 4.3156740178152 -1.56717783477134 2.30886867608555e-21 1858.20812361042 183.962705400169 10.1010045463743 5.27493524478706e-21 -733.513120204588 738.148742978213 -0.993719934067866 0.321110045288532 CNBP other 3.38133817612729e-17 1 7.86440095645302e-17 10.1010045463743 -0.993719934067866 0.000116058374055273 8.45976027397283 166.454453583303 0.0508232738257082 0.959498053935651 -1683.00590302812 440.504961133088 -3.82062871369032 0.000159902991272995 MT1E other 0.993227565165023 1 1 0.0508232738257082 -3.82062871369032 2.66447988747617e-08 452.338648308392 75.9314852721279 5.95719478800227 6.79865673814873e-09 33.6439087242137 170.039997532073 0.197858793298722 0.843281962839392 DUS1L other 0.000303111231999289 1 8.83757389391953e-05 5.95719478800227 0.197858793298722 3.47399722369054e-11 441.219569449383 64.7419991889418 6.81504394329462 4.73528903261968e-11 -110.572806327494 144.982405425831 -0.762663621166503 0.446229379690901 GPS1 essential 4.40780767741856e-07 1 6.46887834746174e-07 6.81504394329462 -0.762663621166503 1.44875537767238e-06 167.418270358983 31.757154865353 5.27182838225967 2.4991261148122e-07 48.6297710430654 71.1165666729352 0.683803694668129 0.494597097457561 RFNG other 0.0148251137797215 1 0.00306292896631383 5.27182838225967 0.683803694668129 0.00569737239703257 230.812433307603 72.9209188365128 3.16524307414556 0.00169949834297806 227.385421171247 163.29817353841 1.39245538541044 0.164757419061117 DCXR other 1 1 1 3.16524307414556 1.39245538541044 0.101148651556829 56.4040014727382 33.1506536500621 1.70144462513886 0.0898719962455114 -33.9618603459868 68.5569654081317 -0.495381616496673 0.620685161194674 ZNF32 other 1 1 1 1.70144462513886 -0.495381616496673 0.0228032743554116 2.53195841841093 9.96227771460794 0.254154570967065 0.799539889689329 45.1915345101128 18.6920899608901 2.41768227119964 0.0161798475324263 LDB2 other 1 1 1 0.254154570967065 2.41768227119964 4.89895516606962e-05 200.91060894309 46.3427690175646 4.33531731491794 1.95569749467196e-05 232.592483075075 103.779404566299 2.24122005755472 0.025701509023366 RAC3 other 0.437819623191642 1 0.215048496514128 4.33531731491794 2.24122005755472 0.0787239092663698 -1.18835849548058 7.75115828247231 -0.153313666444899 0.878247556442208 -32.4959022468207 15.0727060775225 -2.15594347024924 0.031833111905336 NRG4 other 1 1 1 -0.153313666444899 -2.15594347024924 5.00659076206689e-07 339.786291285713 67.8083000506886 5.01098377384057 8.99034528784848e-07 -331.593547280555 220.554476192612 -1.50345417152619 0.133711302346354 LIMS1 other 0.00529146577642849 1 0.0107407655153926 5.01098377384057 -1.50345417152619 0.280413605401185 3.19795823289921 2.57889039670944 1.24005201499826 0.21586752748287 -2.40959914116147 5.01139042873018 -0.480824468863431 0.630970861302012 TMEM266 other 1 1 1 1.24005201499826 -0.480824468863431 0.044361484797306 4.6252728653544 1.90646380452309 2.42610053984814 0.0158250207255241 -9.62587527432672 13.7429415935763 -0.700423210619336 0.484181697546072 NLGN1 other 1 1 1 2.42610053984814 -0.700423210619336 0.000208396885603947 21.8474776381325 15.652757567986 1.39575902477506 0.163757771930713 -72.225134734023 29.3690620738042 -2.4592251040405 0.0144541994649254 TAPT1 other 1 1 1 1.39575902477506 -2.4592251040405 0.000728819984193268 332.668157660766 86.8365060061434 3.83097124655419 0.00015369811576226 -51.9818693485182 364.24757889966 -0.142710267301015 0.88660910346617 UGP2 other 1 1 1 3.83097124655419 -0.142710267301015 0.472894877408801 19.3433652704565 18.7160038888035 1.03352004975957 0.302141030529199 -8.14823558192601 36.3109583545643 -0.22440155675213 0.822588072036 LINGO1 other 1 1 1 1.03352004975957 -0.22440155675213 1.46404728317158e-09 429.048162566366 226.815161830663 1.89162029162181 0.0594982310731776 -2380.09477782022 468.816991809288 -5.07680996935458 6.72503178964677e-07 HNRNPF other 1.75758876344748e-05 0.0100956177226177 1 1.89162029162181 -5.07680996935458 2.80358802226011e-17 53.7413149191448 11.0977185569089 4.84255521921556 1.9992456783231e-06 -83.4761445180139 17.8785454709687 -4.66906799848807 4.45829188351918e-06 BTD other 3.96455382227802e-13 0.0661744264270752 0.0234291601042684 4.84255521921556 -4.66906799848807 0.0471935524944126 66.3041799050131 39.6648583482777 1.67161015231237 0.0956404418331698 -87.0166430335333 82.3235023336166 -1.05700851599945 0.291355284989605 CSGALNACT2 other 1 1 1 1.67161015231237 -1.05700851599945 5.03848999911475e-13 879.789173090537 179.184456924205 4.90996366645064 1.47374855326913e-06 -850.170113417607 335.370442814838 -2.53501801256528 0.0117340182274095 PCDH7 other 6.6785184938266e-09 1 0.0174182341510878 4.90996366645064 -2.53501801256528 1.10745755776518e-06 263.365763340445 235.655631408202 1.11758739550019 0.264592204532446 -1235.15543392053 330.709634153257 -3.73486377886451 0.000222766585345712 ROBO1 other 0.0114311769112522 1 1 1.11758739550019 -3.73486377886451 2.62260691750451e-06 54.557080945058 17.3425716211713 3.14584723285538 0.00181313966944759 -94.142884104572 36.4868059394637 -2.58018978862571 0.0103242729049153 AVEN other 0.0262732760995602 1 1 3.14584723285538 -2.58018978862571 4.49130537447606e-07 275.979419949959 50.1322448996817 5.50502816106109 7.6305843970405e-08 222.660801273467 308.312412631686 0.722192140669537 0.470708758422675 P2RY1 other 0.00476392761070676 1 0.000955043943133589 5.50502816106109 0.722192140669537 7.26395843625446e-10 294.753424453958 52.0615422901154 5.66163450962383 3.33672868566901e-08 -462.197098399821 216.598635342294 -2.13388739808727 0.0336120165521358 TRIM56 other 8.83006787511093e-06 1 0.000423130564629687 5.66163450962383 -2.13388739808727 0.678047210576255 -1.47856214811609 11.7969346940836 -0.125334435296791 0.90033774042063 -25.9991338241663 29.5617213873871 -0.879486464386312 0.37979959745792 WNT10B other 1 1 1 -0.125334435296791 -0.879486464386312 0.595072477798839 11.929054467107 17.1463446254821 0.695719975753819 0.487110740727432 -19.9511469690837 38.1106604743029 -0.523505673236396 0.600985877996926 CALML6 other 1 1 1 0.695719975753819 -0.523505673236396 0.0467068303877833 20.5949070066066 8.28332341334155 2.48630965844402 0.0134172912623686 17.8653890229464 35.8527506741558 0.498298978098339 0.618615631608875 MUC3A other 1 1 1 2.48630965844402 0.498298978098339 0.638138542743669 -66.2831592013196 71.8876802058095 -0.922037809699178 0.357225881501085 -117.591733138936 247.057328441643 -0.4759694192464 0.634431419220301 ITGAM other 1 1 1 -0.922037809699178 -0.4759694192464 0.245891019903478 -12.4711528177299 8.72450596830891 -1.42943942763412 0.153884923972017 13.099305911294 29.9836234850347 0.436882017206229 0.662501068035933 PYDC1 other 1 1 1 -1.42943942763412 0.436882017206229 0.0101361805945174 69.8845978560014 31.7557297653077 2.20069254816334 0.028512005983335 -185.556020589735 118.99890833912 -1.55930859517586 0.119967189741604 TPST1 other 1 1 1 2.20069254816334 -1.55930859517586 3.70844699836137e-05 207.704632173558 45.5687734716416 4.55804745990842 7.35756366653735e-06 -99.4041547700581 143.144114108097 -0.69443410502364 0.487913867623499 TOR1AIP2 other 0.335503199941753 1 0.0833538387782016 4.55804745990842 -0.69443410502364 2.05275382535909e-10 1473.25780731982 213.212555049351 6.90980794718593 2.66981172708112e-11 -113.832477013277 1312.0651969568 -0.0867582474386948 0.930918450970207 TM4SF1 other 2.54664639574049e-06 1 3.66538452010967e-07 6.90980794718593 -0.0867582474386948 0.0142714894780624 16.5889170051822 13.2885603381337 1.24836073909208 0.212814421726125 -56.2338028136373 25.8594117700876 -2.17459713753755 0.0303948146932854 OTUD3 other 1 1 1 1.24836073909208 -2.17459713753755 0.136935154386209 -5.64475662627363 5.69900119999967 -0.990481740251951 0.322691758458741 -24.4104804642008 12.3047296677542 -1.98382907413001 0.048134474958758 OTUD7A other 1 1 1 -0.990481740251951 -1.98382907413001 0.0881956040302557 25.4018684324881 52.9631011675602 0.479614446142869 0.631847572707405 -395.697315350093 198.469733423649 -1.99374135554184 0.0470764957292063 GUSB other 1 1 1 0.479614446142869 -1.99374135554184 2.01565317152069e-08 251.330315801218 45.4481052964761 5.53005046440748 6.65784883574365e-08 -191.506523323264 95.4865603675813 -2.00558615354923 0.045741985650592 BRD3 other 0.000230751975075688 1 0.000834694508537182 5.53005046440748 -2.00558615354923 4.73922204908835e-06 666.800910779284 194.899254781244 3.4212594169624 0.000704728211445988 -898.945978645713 420.807534227241 -2.13624021798115 0.0334230509686126 KLF13 other 0.0465675958543421 1 1 3.4212594169624 -2.13624021798115 0.28485752014309 7.40691912035263 4.69899650282494 1.57627678928889 0.115950082900401 -3.23548078152605 26.2705644664322 -0.123159926223141 0.902057774572192 ZFPM2 other 1 1 1 1.57627678928889 -0.123159926223141 0.0518325938598103 14.3616560322983 6.66676692227368 2.15421600900969 0.0319837491441634 -11.390042749332 22.9485945736771 -0.496328553487836 0.620009880615725 ZNF764 other 1 1 1 2.15421600900969 -0.496328553487836 0.0234499473657886 22.3281460275176 10.1763895682513 2.19411274281184 0.0289596997422037 -34.2049149296585 35.0295489775349 -0.976458901928618 0.329588774751258 ZNF747 other 1 1 1 2.19411274281184 -0.976458901928618 0.0248271627493276 102.280625737474 44.0813887797342 2.3202677721555 0.0209670393481147 -110.678316112933 151.738606005706 -0.729401165770374 0.466300035906683 ZNF768 other 1 1 1 2.3202677721555 -0.729401165770374 0.05700631913058 2.41914549859366 7.5584824623177 0.32005703666763 0.749137280945892 -37.6515468146595 17.1453941765997 -2.19601523457809 0.028819563224218 TAS1R3 other 1 1 1 0.32005703666763 -2.19601523457809 4.75705369214738e-06 222.981928464234 59.381717423794 3.75506028013406 0.000206146592779281 -457.29622623812 167.006498268926 -2.73819420787895 0.00652689694119312 MAP3K2 other 0.0467270023343821 1 1 3.75506028013406 -2.73819420787895 3.90031154290014e-06 82.5750693927236 23.7588223422891 3.47555397330219 0.000581314173167459 -139.516108694811 53.893671945551 -2.58872894828478 0.0100798646550916 PUSL1 other 0.0385662805361965 1 1 3.47555397330219 -2.58872894828478 0.00966866735355895 332.984774936713 119.52075914443 2.78599949766325 0.00565561536770006 -158.629137271852 262.58173531072 -0.604113370962918 0.546197651904955 SF3B5 essential 1 1 1 2.78599949766325 -0.604113370962918 1.37654179533636e-13 20.5570083553102 7.33923999683153 2.80097235738101 0.00540485157081891 -52.412525981975 10.5173509046025 -4.98343418008795 1.02480957360915e-06 ZNF35 other 1.84511662246886e-09 0.0153536970318122 1 2.80097235738101 -4.98343418008795 5.1547778805323e-06 1049.74925017028 348.694646021165 3.01051152390382 0.00281557461050201 -1960.25440793489 676.16470767278 -2.89907826553338 0.00400123767545231 IFFO2 other 0.0504652754504112 1 1 3.01051152390382 -2.89907826553338 1.50361928102804e-19 380.688362056612 38.3470660098377 9.92744430457729 2.00688042509241e-20 105.796350141932 73.1968010027626 1.4453684955158 0.149332981969899 NLGN2 other 2.17528601386327e-15 1 2.98563600840997e-16 9.92744430457729 1.4453684955158 0.186941151051364 25.0023136568282 26.5134433232626 0.943005152216177 0.346396388186833 -104.898277263632 74.5670135282326 -1.40676516733388 0.160476641767641 MYO7B other 1 1 1 0.943005152216177 -1.40676516733388 6.42661160235001e-11 1269.97594511163 183.195430245805 6.93235602770013 2.30220167545408e-11 -451.812112475163 350.23387309194 -1.29002974066006 0.197974706774758 CHD3 other 8.09495997432007e-07 1 3.16391576257655e-07 6.93235602770013 -1.29002974066006 5.70416563478665e-05 76.7181004926179 158.826000103053 0.483032377840151 0.629405124324314 -1044.75576820633 271.484798380244 -3.8483030152688 0.00014375534942526 TMEM154 other 0.505560200211141 1 1 0.483032377840151 -3.8483030152688 0.300644284533195 7.41708314175481 8.87641389962761 0.835594557174263 0.404006489250477 -8.43117166103591 12.714928125621 -0.66309235708905 0.50774876737781 MYRIP other 1 1 1 0.835594557174263 -0.66309235708905 0.204120418495823 318.93088488144 182.501456205075 1.74755254841945 0.0815128747167823 42.4343436362909 746.488142150766 0.0568453016735537 0.95470435317408 ALCAM other 1 1 1 1.74755254841945 0.0568453016735537 1.77755805381584e-19 2084.82180313664 222.50795689537 9.36965056093245 1.37365439821977e-18 -555.657823549641 770.835528134464 -0.720851340226125 0.471528908891334 YWHAG other 2.56803812034774e-15 1 2.02572814105469e-14 9.36965056093245 -0.720851340226125 1.17238200092256e-12 247.803273644188 33.5328853010317 7.38985838586826 1.30691186439647e-12 -134.729316984517 98.1517519026534 -1.37266339492484 0.170824296382665 UBE2E3 other 1.54191680761335e-08 1 1.83202905151097e-08 7.38985838586826 -1.37266339492484 1.29757382760954e-14 235.776410262845 30.4522897212432 7.74248545581023 1.29289354741118e-13 -171.088079716742 58.1272682043647 -2.94333597641692 0.00348435498147357 CNTROB other 1.77261560589739e-10 1 1.83668457345232e-09 7.74248545581023 -2.94333597641692 5.54973725436368e-14 447.91683706343 56.1449678644023 7.97786256009995 2.67672748258443e-14 -165.171282861291 107.169399583865 -1.5412168352407 0.124252286989081 TRAPPC1 essential 7.49270026711641e-10 1 3.83227073681613e-10 7.97786256009995 -1.5412168352407 0.0827774745289327 12.4037682577383 5.58176963879091 2.22219279196644 0.0269691448542599 -2.02698597126443 10.6544704460316 -0.190247462934153 0.849235850329348 KCNAB3 other 1 1 1 2.22219279196644 -0.190247462934153 0.0826992195263929 2.20345485474418 1.6564561723488 1.33022224887469 0.184392303770449 -6.77286698936955 4.97441002179642 -1.36154176267996 0.174300391317128 SERPINA9 other 1 1 1 1.33022224887469 -1.36154176267996 0.761734994472628 4.97452841268554 8.07424027142858 0.616098635346332 0.538267414843945 7.26384018586169 12.2691541534794 0.592040828161064 0.554241307583965 FAM153A other 1 1 1 0.616098635346332 0.592040828161064 1.82486259783074e-05 17.9866612304251 3.79778590034034 4.73609142337729 3.27949038296942e-06 -3.44251633825383 12.9168375582465 -0.266513867866677 0.790015132113578 GPR37L1 other 0.170095442743803 1 0.0379830576155518 4.73609142337729 -0.266513867866677 0.000456218231110881 33.3576711644672 16.4611347844377 2.02645027826414 0.043547746897778 -62.9157896136565 25.065102973307 -2.51009499863849 0.0125630215053204 SIMC1 other 1 1 1 2.02645027826414 -2.51009499863849 1.28687081988559e-08 65.2675798423256 17.1690946214372 3.80145728597901 0.000172500005800127 -83.5208474089095 29.4487325755853 -2.83614404098847 0.00485986464544402 TMEM192 other 0.000148556367447593 1 1 3.80145728597901 -2.83614404098847 0.000780043235254956 19.0717952946745 8.36206866902744 2.28075085837493 0.0232202540167243 -36.655386170846 21.3494765276922 -1.71692201086526 0.0869610313818825 ZNF778 other 1 1 1 2.28075085837493 -1.71692201086526 0.0979191069850609 27.5753841408705 40.643708435798 0.678466242430349 0.497977419810777 -145.051254610937 88.6237370845198 -1.63670884779552 0.102696340575259 NIPA1 other 1 1 1 0.678466242430349 -1.63670884779552 6.74486561690949e-21 295.622262869129 48.3458088222788 6.11474438158328 2.81544661808851e-09 -333.309200530435 74.2729835037589 -4.48762369312345 1.0059342832577e-05 UBE2E1 other 9.8508762334963e-17 0.148093645181199 3.70203075812458e-05 6.11474438158328 -4.48762369312345 8.01955576195127e-07 201.018238305349 48.3691977330249 4.15591425383721 4.1727719767147e-05 -5.59452261873775 89.4996145918503 -0.0625089017896975 0.950196967687263 SIK2 other 0.00835798101510562 1 0.448280893458461 4.15591425383721 -0.0625089017896975 0.162114134664664 -42.7695210292096 56.3639206763411 -0.758810255141854 0.448535278817192 -190.571398493136 99.6548878983554 -1.91231361062302 0.0567456917667703 RNF150 other 1 1 1 -0.758810255141854 -1.91231361062302 0.013464364112077 8.49779491569469 5.57460513643227 1.52437611413196 0.128402437140602 -28.2643547221234 11.8864989779613 -2.37785362826583 0.0180007323761406 CCDC144A other 1 1 1 1.52437611413196 -2.37785362826583 0.747470207167928 -1.09058792589561 4.14641198679813 -0.263019673242303 0.79270521126609 -7.34772953071124 9.67189820885697 -0.759698807001775 0.44799569204616 VGLL2 other 1 1 1 -0.263019673242303 -0.759698807001775 0.874671188298773 0.709911188108816 2.32823561531361 0.304913808310243 0.760636408864061 3.85450873720192 8.46864949293568 0.455150344859265 0.649319680280229 HOXD4 other 1 1 1 0.304913808310243 0.455150344859265 1.08696398495099e-05 109.387093779982 22.8449817515075 4.78823292440422 2.57639039000432e-06 -28.841350286653 43.6064543438043 -0.661400949026044 0.5088311542907 CHRNB1 other 0.103326796409441 1 0.0300329827762804 4.78823292440422 -0.661400949026044 1.12368367598627e-09 121.837102207641 30.6487577209398 3.97527049275476 8.72277962738327e-05 -187.695106565561 54.2359392349222 -3.46071459650697 0.000613061621159361 USP38 other 1.35460067140145e-05 1 0.910309281913718 3.97527049275476 -3.46071459650697 4.81088063732994e-07 141.128514779551 26.0795301285397 5.41146692766176 1.22757110385641e-07 -11.144266968008 64.6808927553249 -0.172296121671737 0.863313648855246 SLC16A5 other 0.00509231715461374 1 0.00152292471144427 5.41146692766176 -0.172296121671737 2.5743727157332e-12 55.052404687058 7.66732353637844 7.18013325326054 5.18827476054635e-12 -17.611006856874 33.9994866822846 -0.517978610131494 0.604842656237263 NANP other 3.3587840822171e-08 1 7.20651364239888e-08 7.18013325326054 -0.517978610131494 1.44842491167069e-05 1.99420367451546 4.58290505227208 0.43513964434563 0.663755314817678 -28.3450182281953 8.39894699540121 -3.37482999282117 0.000829787641842793 ANKK1 other 0.136354721184679 1 1 0.43513964434563 -3.37482999282117 9.91394878022279e-10 26.656397203018 4.11887356473844 6.47176874551883 3.66263658318359e-10 -9.34247066948105 7.61258216943658 -1.22724069987576 0.220639889114118 ADPRM other 1.19839812855333e-05 1 4.92258356779874e-06 6.47176874551883 -1.22724069987576 0.342525499022894 28.4636449006941 27.9255844078183 1.01926765381229 0.308845889983058 -26.1673413665202 40.0417231034911 -0.653501880997692 0.513902065048969 FABP6 other 1 1 1 1.01926765381229 -0.653501880997692 1.44834929691339e-09 51.3148830233906 14.2922071006711 3.59040998090359 0.000381949400292787 -82.1634657126877 20.4932004611011 -4.00930376241842 7.58336612651408e-05 PWWP2A other 1.73946750559298e-05 1 1 3.59040998090359 -4.00930376241842 6.66945703940633e-05 4.44182382146292 1.64999969529699 2.69201493438059 0.00748058172518316 -8.55322121911818 3.54345641331459 -2.41380737377757 0.0163551050131242 USP50 other 0.586045190052634 1 1 2.69201493438059 -2.41380737377757 1.24801679423549e-25 408.290906166916 53.0260702612592 7.69981452812304 1.73902147912327e-13 -464.517445318757 109.917402827363 -4.22605914414055 3.11077451682506e-05 USP47 other 1.8649114956261e-21 0.451964429549512 2.46575855524889e-09 7.69981452812304 -4.22605914414055 1.58467556729695e-19 681.693435667592 139.81423026767 4.87570853383459 1.71064515627725e-06 -1057.65058016971 208.073594166064 -5.08306007981771 6.33070513320692e-07 PDCD6IP other 2.29175780542485e-15 0.00950681989853682 0.020132582844227 4.87570853383459 -5.08306007981771 4.29871208095086e-24 72.9032774996437 12.2026798570584 5.97436615183131 6.20307799905845e-09 -142.375172973525 27.3159002077725 -5.21217210088553 3.37136733547857e-07 ZNF212 other 6.38143808417155e-20 0.00507761634396428 8.07330601577457e-05 5.97436615183131 -5.21217210088553 2.34993572013159e-08 10.9090279264493 4.55884029109871 2.39293926302913 0.0173031014873064 -33.3803703852376 7.48880790786919 -4.4573676873407 1.15730341151458e-05 MRAP other 0.000268080666952612 0.170077309356182 1 2.39293926302913 -4.4573676873407 0.523215124418904 4.07617194098247 6.23771146606616 0.653472345291586 0.51392254554243 -24.0582243340702 26.7082848467421 -0.900777585386761 0.368386123623712 FAM161A other 1 1 1 0.653472345291586 -0.900777585386761 2.32584198275215e-26 213.058718927094 31.799893632661 6.69998212535734 9.52132297821987e-11 -362.520304364289 71.1845866041546 -5.09267977322398 6.06984270608553e-07 ZNF282 other 3.48294836917135e-22 0.00911872469735229 1.29404300596986e-06 6.69998212535734 -5.09267977322398 7.51816175447886e-15 286.858925755992 55.9757931191824 5.12469604754359 5.16491741698082e-07 -274.242842211553 83.3039987296453 -3.29207296640802 0.00110568065898535 GLB1 other 1.0314917927145e-10 1 0.00623767076448773 5.12469604754359 -3.29207296640802 0.100010528224451 6.65297760481953 8.38775527902914 0.793177361940106 0.428262198550053 -42.2334688660098 25.0675366622207 -1.68478735805181 0.0930045673145265 GON7 other 1 1 1 0.793177361940106 -1.68478735805181 0.191549876082995 6.35490942060481 25.4664225757975 0.249540719812146 0.803102652591101 -60.0201490511461 37.0530314432238 -1.61984449620849 0.106250711702663 FAXDC2 other 1 1 1 0.249540719812146 -1.61984449620849 2.09911122134284e-05 614.617849740471 136.523930295918 4.50190562495729 9.44406704334894e-06 208.673875533668 203.176921347452 1.02705501269416 0.305170272976623 CRTAP other 0.194587610218481 1 0.106264642371762 4.50190562495729 1.02705501269416 0.021225458783263 82.765155889883 30.0601051643448 2.75332223348484 0.00623958579476657 78.3272839234881 55.2333536639801 1.41811566250355 0.157139276552169 HSPB2 other 1 1 1 2.75332223348484 1.41811566250355 0.277109195888973 297.448135809965 202.423144701059 1.46943738202092 0.142705909532763 162.620489443287 383.286933333716 0.424278719936686 0.671650342964606 SLN other 1 1 1 1.46943738202092 0.424278719936686 5.18906240327002e-13 242.643545984598 31.0434404196424 7.81625820800031 7.91811105750257e-14 -31.8792309097284 59.2556554458362 -0.537994739402861 0.5909546530479 ELP5 essential 6.8760265905731e-09 1 1.12833082569412e-09 7.81625820800031 -0.537994739402861 0.0550781160431854 19.3085705681233 8.39059443779265 2.30121604747743 0.0220217458653573 6.34892912186211 12.4870060688308 0.508442863474685 0.611493133412828 CMTM8 other 1 1 1 2.30121604747743 0.508442863474685 1.02434462467603e-10 1108.56944780897 162.825693659968 6.8083201298931 4.88729866024915e-11 -453.918009083297 310.801350327765 -1.46047630940022 0.145140315393825 GABARAP other 1.28012347745763e-06 1 6.67458378030227e-07 6.8083201298931 -1.46047630940022 0.110626169005152 42.5045456590053 20.2131002211795 2.10282169453989 0.0362620713532652 1.52504824086668 37.2325338529742 0.0409600981466604 0.967353249940776 LGALS9B other 1 1 1 2.10282169453989 0.0409600981466604 5.08850973664715e-09 180.171209363456 28.3981246148379 6.34447562320074 7.64269408720038e-10 -11.8152425058534 52.7588368800946 -0.223948123282285 0.822941027460661 STX8 other 5.98866710906003e-05 1 1.02052894146387e-05 6.34447562320074 -0.223948123282285 0.202112456346988 -16.0921208614102 83.2945822620897 -0.193195288629645 0.846930142736018 -331.548872030228 190.480475039563 -1.7405924253463 0.0827284382254376 CDK1 essential 1 1 1 -0.193195288629645 -1.7405924253463 2.23665857409586e-13 3355.7181180344 443.157874153647 7.57228589121479 3.9606645403293e-13 -1820.24240129174 942.303238693988 -1.9316949433545 0.0542798883984778 UBB other 2.98772852327725e-09 1 5.58572520122641e-09 7.57228589121479 -1.9316949433545 3.44936466043777e-28 192.964144258963 30.3402064672163 6.36001420977367 7.03787794633631e-10 -235.881386528536 55.4337686062108 -4.25519304314641 2.75352486343526e-05 NFRKB other 5.19232862335698e-24 0.400582797132562 9.40612387527848e-06 6.36001420977367 -4.25519304314641 0.801648272251555 1193.04637438094 3428.3079693085 0.347998600202064 0.728072205746078 -8760.60420785956 16472.3727919816 -0.531836203471793 0.595211953793555 FABP4 other 1 1 1 0.347998600202064 -0.531836203471793 1.31154126881316e-05 24.7122217691619 11.7253742064105 2.10758491235625 0.0358518589938806 -43.2839501556226 21.4231132962698 -2.02043230398073 0.0441791782213452 PRDM10 essential 0.123927534490155 1 1 2.10758491235625 -2.02043230398073 1.34303945984496e-05 163.356604951418 34.2658182302903 4.76733413612209 2.84229615326778e-06 139.000851920125 146.717468222115 0.947404924611244 0.344149599863859 B3GNT2 other 0.126809785798561 1 0.0330246390048183 4.76733413612209 0.947404924611244 0.115710102156027 450.791773990493 719.302913688464 0.626706447884256 0.531298509605267 -4166.28814882201 2334.69432082642 -1.7845111934599 0.0752879226573269 FOS og 1 1 1 0.626706447884256 -1.7845111934599 2.43863479883722e-29 2256.01070850492 187.841326854983 12.0101936367102 1.10759973822227e-27 -848.484275743606 609.690397020648 -1.3916641624829 0.164990709559202 TMED10 other 3.68038763840513e-25 1 1.67701676364234e-23 12.0101936367102 -1.3916641624829 1.88730280251246e-12 70.3167637298933 13.4686151480263 5.22078646966147 3.24168782025398e-07 -60.6471740607966 22.3391725770289 -2.71483528996769 0.00699639304713953 SETMAR other 2.4697244473678e-08 1 0.00394999660897948 5.22078646966147 -2.71483528996769 0.00934975072042798 39.3584718720559 34.5966989014631 1.13763662782264 0.256136822623329 -133.47701335906 59.8792276028543 -2.22910379279337 0.0265120247181139 SMAD1 other 1 1 1 1.13763662782264 -2.22910379279337 0.586865362607926 244.661585335567 248.038283289256 0.98638638395287 0.324698187935369 -24.0827428711798 1065.82847007194 -0.0225953270600422 0.981987332339493 CST2 other 1 1 1 0.98638638395287 -0.0225953270600422 0.0819346884897893 7.51465644042867 3.46652659416345 2.16777694799198 0.0309125656715925 2.60975603012574 6.68666764142198 0.390292470042784 0.696579963325542 EMX2 other 1 1 1 2.16777694799198 0.390292470042784 0.51895454391769 485.668360510599 444.243147989884 1.09324896221395 0.275117208118 -55.8334314217485 1908.92707562336 -0.0292485931677176 0.976684789419632 CST1 other 1 1 1 1.09324896221395 -0.0292485931677176 1.03807001066293e-05 47.7204533941914 20.3044555217964 2.35024541007586 0.0193717927357502 -118.760035864252 46.8120524521354 -2.53695425949722 0.0116598151894574 TCAF2 other 0.0989695948166038 1 1 2.35024541007586 -2.53695425949722 0.472515862871332 10.2772330380686 10.5764485585315 0.971709263387707 0.331929119238166 -26.2641698114202 35.9179572653016 -0.731226712516653 0.465175780567022 LRRN2 other 1 1 1 0.971709263387707 -0.731226712516653 0.193015483236411 37.6687012587289 36.052614550433 1.04482578388414 0.296892110977836 -179.072840261206 121.668300962546 -1.47181179357745 0.14205446056441 SLC30A1 other 1 1 1 1.04482578388414 -1.47181179357745 0.877252181734107 1.76269833202727 4.52699583252892 0.389374851940733 0.697260316238297 3.58428557844589 7.80143621755022 0.459439195360289 0.646233713658425 DCLK2 other 1 1 1 0.389374851940733 0.459439195360289 0.304414052782112 38.3066242978824 45.1219701242092 0.848957263887947 0.396541696022074 149.333880798239 106.687411264278 1.39973291158335 0.162565036171412 GPRC5C other 1 1 1 0.848957263887947 1.39973291158335 0.0620503950505244 41.5766896862713 23.5084718566321 1.76858325542508 0.0779160950886394 138.842098664889 76.6277919282921 1.81190264225304 0.0709385116964532 TMEM182 other 1 1 1 1.76858325542508 1.81190264225304 0.31223316702148 -132.292922972669 1048.0356402365 -0.126229412334504 0.899629602641289 -4293.02044951436 2831.90203957761 -1.51594948890064 0.130519298394434 KRT8 other 1 1 1 -0.126229412334504 -1.51594948890064 0.994241225896495 43.6077782374846 413.681241049955 0.105413961065299 0.916113383913703 46.3728695930705 1123.3606061575 0.0412804840572884 0.967098035137763 KRT78 other 1 1 1 0.105413961065299 0.0412804840572884 3.5821720688892e-15 173.42356720163 20.439321964448 8.48480040107402 8.3090972829727e-16 -31.1085215696943 42.7785515578342 -0.727199038696701 0.467639047339967 ADORA2B other 4.93551667651554e-11 1 1.20437256960345e-11 8.48480040107402 -0.727199038696701 0.0980843666973323 108.117913933524 53.9854021008451 2.00272499094401 0.0460500641899154 -72.2188065236993 173.61061222128 -0.415981520943265 0.677702359184597 SDR9C7 other 1 1 1 2.00272499094401 -0.415981520943265 0.163577964692817 87.9248118444185 57.4163471853917 1.53135502613076 0.126672731753938 -42.8946934828401 115.969722806772 -0.369878382431861 0.711718544952258 MGMT other 1 1 1 1.53135502613076 -0.369878382431861 0.0438616237222902 27.6322969008195 11.1420999592517 2.47999003795289 0.0136527693347662 2.50049621575267 31.8339642912293 0.0785480624680348 0.93744119370079 METTL7B other 1 1 1 2.47999003795289 0.0785480624680348 0.0614765112253264 50.2341952031053 23.0622841844528 2.17819686902351 0.0301256863058836 -31.4107606636167 63.5045013744388 -0.494622585545721 0.621208093880611 KRT86 other 1 1 1 2.17819686902351 -0.494622585545721 2.92025011274948e-18 263.379506462887 49.2929649676323 5.34314595674722 1.74490058502629e-07 -417.341202050901 74.6503627468093 -5.59061184292422 4.87398584611661e-08 HARS essential 4.17449753617538e-14 0.000737921457102055 0.00215111344122041 5.34314595674722 -5.59061184292422 1.58916631794743e-07 49.6231833346059 10.2617517689463 4.8357419329489 2.10733450373069e-06 -8.16422165055974 22.0608287180275 -0.370077740728214 0.711581415982047 NFXL1 other 0.00173378045288065 1 0.0246705650351752 4.8357419329489 -0.370077740728214 0.407864963014558 -83.3060966310815 637.262289810464 -0.130724974571865 0.896075274265124 -2307.92426253226 1729.92224953692 -1.33412022601019 0.183116079227402 KRT75 other 1 1 1 -0.130724974571865 -1.33412022601019 0.0118750475519252 17.3350989568903 6.06559896993618 2.85793687363949 0.00454891590435496 47.3008184629671 36.9896007573177 1.27875990804279 0.201925905761716 DENND5B other 1 1 1 2.85793687363949 1.27875990804279 0.000461018577211592 235.990583358011 148.545133131931 1.58867933524564 0.113120309304472 -631.753716316255 218.113516785838 -2.8964445928244 0.00403409724744423 CD14 other 1 1 1 1.58867933524564 -2.8964445928244 0.000975192465358633 23.6189334266564 7.90182711728384 2.98904709962512 0.00301523603660308 -13.4504180687538 11.6025026552284 -1.15926869128469 0.247210980207833 DNAJC18 other 1 1 1 2.98904709962512 -1.15926869128469 0.529706544200241 9525.13737349229 12589.3029673165 0.756605619725001 0.449844586607602 -22902.5150652049 34175.1201311464 -0.670151706192017 0.503245916705581 KRT6C other 1 1 1 0.756605619725001 -0.670151706192017 2.07970188782696e-11 63.5561899905086 9.49644057180312 6.69263283542467 9.8213337537721e-11 -37.0446056350583 29.4095019620936 -1.25961349780101 0.208726748416448 RIOX1 other 2.65453148962233e-07 1 1.33442461712501e-06 6.69263283542467 -1.25961349780101 1.07457465104278e-05 10.9423608905161 2.49531669912192 4.38515916411196 1.57461304442505e-05 -1.9555662637629 3.66395242486016 -0.533731347190606 0.59389795865509 SPATA24 other 0.10223503230021 1 0.174278171756965 4.38515916411196 -0.533731347190606 1.97599702647006e-17 339.090570333318 37.5705837506676 9.0254272487127 1.79171564875753e-17 -81.3821001107559 191.684960479299 -0.424561738736642 0.671445103005991 RALGAPB other 2.80038298591337e-13 1 2.62343005291077e-13 9.0254272487127 -0.424561738736642 0.604154819052763 20.6947020537551 26.8257299345198 0.771449727715511 0.441009688906432 -37.0482846833131 76.6434812059449 -0.483384680606593 0.629153200401351 PYM1 other 1 1 1 0.771449727715511 -0.483384680606593 0.0108663825028382 -180.226369827981 82.5030301437386 -2.18448182465525 0.0296521961410298 -327.902087920961 121.141808356364 -2.70676236693091 0.00715890581536272 MZB1 other 1 1 1 -2.18448182465525 -2.70676236693091 0.915845392111907 -886.709488346435 8921.1887782933 -0.0993936470108046 0.920887962699862 9203.22159902307 24225.6864444546 0.379895183574034 0.704275229068441 KRT4 other 1 1 1 -0.0993936470108046 0.379895183574034 0.338967801230901 4.66000915282527 3.34728102929643 1.39217744552652 0.164835397599347 4.51976633375505 4.91491859461956 0.919601463735923 0.358473736075804 SLC23A1 other 1 1 1 1.39217744552652 0.919601463735923 0.826564121848387 -20.5516948565091 36.4137735878088 -0.564393437745482 0.572883019695464 -35.3351179322282 98.849403340477 -0.357464149889907 0.720980739600241 KRT74 other 1 1 1 -0.564393437745482 -0.357464149889907 0.0122106042414361 99.5167095770395 36.2624251609775 2.74434787897559 0.00640642068251585 -75.2199820332107 114.508444159424 -0.656894629783686 0.511722292916668 NPAS2 other 1 1 1 2.74434787897559 -0.656894629783686 0.101701962809397 17.3933176209622 23.4148171294365 0.742833801554476 0.458128977404784 -116.019811898767 63.5622313899946 -1.82529482306737 0.0688914940257327 KRT72 other 1 1 1 0.742833801554476 -1.82529482306737 0.847936618574522 6.47595270506538 11.4429982361231 0.565931460569674 0.571839499133037 0.255136387643199 36.1269186151601 0.00706222388798293 0.994369635701507 LONRF2 other 1 1 1 0.565931460569674 0.00706222388798293 1.89399285649366e-14 114.572288952472 18.7249211841944 6.11870607226809 2.76211600699604e-09 -93.7574269678965 34.5388487039166 -2.71454986156689 0.00699764439477479 NUDT9 other 2.57942887125872e-10 1 3.63383981880399e-05 6.11870607226809 -2.71454986156689 0.000703256762786411 478.790173001045 138.533233196865 3.45613945442717 0.00062195033286111 -399.568737925818 395.801690423332 -1.00951751241501 0.313489227436552 PA2G4 other 1 1 1 3.45613945442717 -1.00951751241501 0.741167356159248 22.5859334154912 31.8892139795776 0.708262468618875 0.479301104998133 -3.00371106878733 58.397562002476 -0.0514355559682436 0.959010746381128 ELOVL6 other 1 1 1 0.708262468618875 -0.0514355559682436 0.475967861035404 10.0824032995979 9.50609587357579 1.06062503825825 0.289665216908087 -10.0332050926568 26.1760662404813 -0.38329690185229 0.701755744998281 KRT83 other 1 1 1 1.06062503825825 -0.38329690185229 2.7998533935776e-05 449.650820463321 154.475445236649 2.91082391621838 0.00385844898337265 -564.250831188331 316.583597532281 -1.78231227260849 0.0756493408458787 PFKFB3 other 0.256746556191066 1 1 2.91082391621838 -1.78231227260849 1.90750611757121e-06 43.1122575208691 9.87368592033515 4.36637926998246 1.70785026529536e-05 -47.2105670207222 30.3241285011153 -1.55686475932807 0.120491016415172 TMC7 other 0.0193020544037031 1 0.188597904796567 4.36637926998246 -1.55686475932807 0.0723771582205994 215.286886486404 196.055272684354 1.09809281606526 0.272989507743753 -978.630033062208 599.775885385778 -1.63165951967667 0.103734916360943 ARL6IP1 other 1 1 1 1.09809281606526 -1.63165951967667 0.164905381098249 -53.864078141485 41.3791710256458 -1.30171960448655 0.193954438208656 -165.040948520934 91.8020598340712 -1.79779134388966 0.0731585622098891 SERPINB9 other 1 1 1 -1.30171960448655 -1.79779134388966 0.394184394720486 30.3636847848375 33.7190441825162 0.900490672881573 0.368538488224149 -75.4631941023835 91.9497203927575 -0.820700637044324 0.412429666725751 SMAGP other 1 1 1 0.900490672881573 -0.820700637044324 0.0590939588779447 19.7101211042801 8.27390450665897 2.38220311684973 0.017793263864418 4.12839441530763 47.3686458625436 0.0871545795775455 0.930603153401981 IRX1 other 1 1 1 2.38220311684973 0.0871545795775455 0.000384080437170304 82.0598778974337 23.3770528789792 3.51027472634168 0.000514491019873372 13.1566899060592 44.6887240813671 0.294407374041472 0.768644953270048 CDH2 other 1 1 1 3.51027472634168 0.294407374041472 3.2581860671226e-10 165.611634262302 24.2229783874128 6.83696412611096 4.14482703106111e-11 150.111439113607 140.267908234449 1.07017664270508 0.285351406287214 IRX2 other 4.01343359748162e-06 1 5.66887993038228e-07 6.83696412611096 1.07017664270508 0.00150137454118998 83.1618729928637 44.7250554363956 1.85940234576411 0.063945728569976 -144.891583705585 67.1905977722461 -2.15642647200013 0.0318422287507905 EMB other 1 1 1 1.85940234576411 -2.15642647200013 0.114450461386749 -49.5786964267001 26.3573038841103 -1.88102306080664 0.0608794351227959 62.5811065702612 95.5654174204758 0.654850972867227 0.513035604918023 SIX2 other 1 1 1 -1.88102306080664 0.654850972867227 1.21509102496052e-17 86.5320193333749 9.18553439998925 9.42046652543985 1.23206457546343e-18 52.9675475488041 44.1103719532694 1.20079575853312 0.230774535480719 DLGAP1 other 1.72603680095642e-13 1 1.81741845526611e-14 9.42046652543985 1.20079575853312 0.100395876116872 74.802212255084 176.986448692195 0.422643726724953 0.67283907261766 -1005.9506253282 505.665925481181 -1.98935814069528 0.0475127123983289 STAT2 other 1 1 1 0.422643726724953 -1.98935814069528 1.27808955373632e-07 68.8999100486942 19.8664282315329 3.46815790164702 0.000595988860130627 -89.7881437367148 28.5162928816566 -3.14866115695116 0.00179529915411754 NUDCD2 other 0.00140155300462725 1 1 3.46815790164702 -3.14866115695116 9.2092228370375e-06 107.26870123264 28.0237267799428 3.82778143945559 0.000155526462986053 -134.191489960751 65.5419068791939 -2.0474151020368 0.0414335487691556 IRF2BP1 other 0.08815989021896 1 1 3.82778143945559 -2.0474151020368 4.00808065109972e-14 742.449829679342 136.075742774398 5.45615121800406 9.80023102412293e-08 -759.248004786071 203.401813874951 -3.7327494299183 0.000224331473804789 HSPA4 other 5.4221315048077e-10 1 0.00122101078329548 5.45615121800406 -3.7327494299183 0.137677651605413 10.329633098643 5.17109785879126 1.99757060893402 0.0466094983532826 5.94768178482202 12.0941663821341 0.491781045249064 0.623211304397904 FOXA3 other 1 1 1 1.99757060893402 0.491781045249064 8.81418027766489e-13 112.921102381425 14.5309220582541 7.77108995070835 1.09333022545791e-13 24.3892558161545 72.5708038921338 0.336075315527793 0.737036412397458 COMMD5 other 1.16241409501845e-08 1 1.55515291269133e-09 7.77108995070835 0.336075315527793 0.0265327904770313 -0.824984855515864 40.6517950639621 -0.0202939342338468 0.983821542382521 150.740166649505 59.1473826465124 2.54855176856068 0.0112838607121895 SGCD other 1 1 1 -0.0202939342338468 2.54855176856068 0.307682039613621 26.0489459781426 27.6768551337464 0.941181570386625 0.347321765174455 106.081478994278 77.0791240178697 1.37626731421707 0.16970118859844 GTSF1 other 1 1 1 0.941181570386625 1.37626731421707 0.471808780646728 -2.21892379614509 2.53730174707468 -0.874521053202813 0.382494546410189 -10.4909141181544 10.0059489811444 -1.04846768036934 0.295219382910398 DPY19L2P2 other 1 1 1 -0.874521053202813 -1.04846768036934 1.2646258661065e-10 39.1703144679675 5.61599096186256 6.97478231962404 1.7908558042045e-11 4.6907080593833 28.0475648495971 0.167241187765742 0.867286911548836 ZNF16 other 1.57559736658209e-06 1 2.46547118564833e-07 6.97478231962404 0.167241187765742 3.12176011054876e-25 194.340526640006 17.2784209263498 11.2475860767829 6.20793179341568e-25 -10.5692278358475 68.1381307773582 -0.155114731139052 0.876829277486828 ARMC10 other 4.6579782609498e-21 1 9.35162845360139e-21 11.2475860767829 -0.155114731139052 0.00104179471601812 61.3076671282893 24.5182749269987 2.50048860740929 0.0129020403269865 -154.155319889507 64.5326360908367 -2.38879626228994 0.0174827877622598 RNF34 other 1 1 1 2.50048860740929 -2.38879626228994 0.122919539466171 16.0745756374124 8.24947932709247 1.94855638762815 0.0522249456702859 -12.3426217061923 32.6608864035496 -0.37790222695398 0.705754555793592 ACYP2 other 1 1 1 1.94855638762815 -0.37790222695398 1.26493669498151e-06 220.168354326036 48.7541728000753 4.51588739345192 8.88595907843387e-06 -216.09118965972 139.572898390019 -1.54823172802416 0.122557995258411 TRABD other 0.0130048141611049 1 0.100179631072187 4.51588739345192 -1.54823172802416 0.000453234293614259 3.63389729332001 1.18374834696017 3.06982248604762 0.00233193117167731 -10.0725621430895 6.77230421142489 -1.48731684647259 0.137950846581134 TMEM133 other 1 1 1 3.06982248604762 -1.48731684647259 0.00874622175115775 75.0651518354278 45.351240762267 1.65519510764705 0.0988683577308577 -272.425111088124 123.111192507697 -2.21283788694592 0.0276165153679507 ATF7 other 1 1 1 1.65519510764705 -2.21283788694592 9.6082450839273e-06 64.5911846128646 13.5022331321071 4.78374088055645 2.64084545468943e-06 8.68751829201695 53.221757487956 0.163232457965766 0.870439423897498 RASA4B other 0.0918356065121772 1 0.0307737720834959 4.78374088055645 0.163232457965766 8.44359974717542e-16 161.725402396438 32.2341277906933 5.01721043753918 8.73787115264525e-07 -119.27633258551 49.0327117287534 -2.43258690739645 0.0155425877236687 SOCS6 other 1.17433585283716e-11 1 0.0104452511758721 5.01721043753918 -2.43258690739645 0.125043481163301 25.7344859346815 26.7566489970177 0.961797792300147 0.336879657134416 97.9839719516003 51.2891622757407 1.91042254550423 0.0569752195721296 CAVIN4 other 1 1 1 0.961797792300147 1.91042254550423 0.0302292890002751 11.9487610069992 8.46900019795599 1.4108821263085 0.159256891811209 -38.7837971325356 20.6492549299546 -1.87821774994285 0.0612662164340708 ZNF296 other 1 1 1 1.4108821263085 -1.87821774994285 0.00627902896250487 44.0661345944958 14.1502190933683 3.11416624037629 0.00201247832823922 32.7599392965253 33.7497800804746 0.970671193068842 0.332449755458178 HOXB9 other 1 1 1 3.11416624037629 0.970671193068842 0.251416022586563 22.49895953323 13.6729645252043 1.64550705092199 0.100856410551381 9.10489369960438 37.763508373712 0.241102961343033 0.809631186846081 POLH other 1 1 1 1.64550705092199 0.241102961343033 0.00516577189805463 175.695167076494 60.3709330567121 2.91026091830396 0.00386603629854192 -167.717042912603 193.476040979158 -0.866862077928659 0.386671193293262 KCNS3 other 1 1 1 2.91026091830396 -0.866862077928659 4.16745802807583e-13 757.690509564284 154.627472341895 4.90010279602167 1.53300342757508e-06 -1011.56190471979 327.164886558135 -3.0919024207081 0.00216600767227081 KIF5B other 5.53396751548189e-09 1 0.0180986384659514 4.90010279602167 -3.0919024207081 0.179572155710539 9.38258958755917 8.86246123434375 1.05868892844347 0.290547509003127 -18.8582062943713 21.020882856636 -0.897117710183042 0.370336915119705 GPR37 other 1 1 1 1.05868892844347 -0.897117710183042 4.33812538893274e-12 244.356805822703 40.0789026494455 6.09689361906927 3.15079630521447e-09 -281.408606609503 118.180042589292 -2.38118552374766 0.0178490545597955 CDCA4 other 5.63262200499027e-08 1 4.1369955487466e-05 6.09689361906927 -2.38118552374766 0.0205141388658708 56.7596135574156 59.5405748311852 0.953293005960148 0.341181963339326 -674.286099772726 273.406754466455 -2.46623789923762 0.0141931748385834 SDR16C5 other 1 1 1 0.953293005960148 -2.46623789923762 9.48585020987001e-05 83.1756716918255 19.3195356265501 4.30526247108757 2.24009802123689e-05 -11.0546937085276 90.0773793795408 -0.122724415215819 0.902404852585433 CHCHD7 other 0.819387741128572 1 0.245402738226502 4.30526247108757 -0.122724415215819 0.0394116309098607 352.242574573517 168.862304140951 2.08597517584207 0.0377725815266648 752.669124931533 313.158088006931 2.4034797559336 0.0168084253972483 HTRA3 other 1 1 1 2.08597517584207 2.4034797559336 0.000141047806272483 131.800432707854 31.2954891377556 4.21148339071163 3.30180179550858e-05 -16.4710905774378 115.939935836316 -0.142065721001361 0.887117495099488 FOXN2 other 1 1 0.357585134453579 4.21148339071163 -0.142065721001361 0.0265017142143104 81.4862010546835 128.846305639202 0.632429472078639 0.527559310613556 829.076141398456 313.113983272725 2.64784131558993 0.00850328934484665 LMOD2 other 1 1 1 0.632429472078639 2.64784131558993 0.35616506934169 -14.4273636578515 39.8528547797961 -0.362015813862489 0.717579904683004 -118.498151119556 83.3054067770587 -1.42245450450389 0.155871432531058 CELP other 1 1 1 -0.362015813862489 -1.42245450450389 5.88796708241402e-07 180.814989304555 36.8798287929527 4.90281531185164 1.52219353135723e-06 -161.977929258518 84.7577300894429 -1.91106969343783 0.0569118115801793 USP32 other 0.00619296377728306 1 0.0179725390247348 4.90281531185164 -1.91106969343783 0.362768744294322 -110.525483981671 248.489277631968 -0.444789751231711 0.656772393737451 -723.385950568935 519.77565834027 -1.39172725571418 0.164971612503634 CEL other 1 1 1 -0.444789751231711 -1.39172725571418 0.129721336241031 17.4342807637581 14.8228259039306 1.17617793508153 0.240420423323353 -51.6355368218084 34.0660224910867 -1.51574892065308 0.130595309079378 PPM1D other 1 1 1 1.17617793508153 -1.51574892065308 0.249014623721765 15.6377709292193 16.6944536868152 0.936704562040839 0.349621371911789 38.9708327982898 23.324835419657 1.67078704295796 0.0957475781789314 GPR27 other 1 1 1 0.936704562040839 1.67078704295796 6.48135314216602e-08 140.324657897269 27.2760683127825 5.14460721714456 4.68375713168972e-07 -213.952920074734 112.16896439968 -1.90741638045598 0.0573617728424985 KBTBD2 other 0.000722087553568717 1 0.00566875125648407 5.14460721714456 -1.90741638045598 3.17655524239213e-22 281.303288698295 28.2743781782537 9.94905305873887 1.79008010396347e-20 -149.370118934358 117.024594495967 -1.27639937209528 0.202748687938973 RIOX2 other 4.6765246278497e-18 1 2.66381820270804e-16 9.94905305873887 -1.27639937209528 0.32961214280092 35.2604249680593 23.6351967358299 1.49186086167017 0.136723868078989 10.8551952487571 65.3950938309255 0.165994031246786 0.868266802170843 TRIAP1 essential 1 1 1 1.49186086167017 0.165994031246786 5.41171439263666e-24 225.863993481432 45.7153283472696 4.94066217277694 1.25913985465888e-06 -488.002084226776 73.5795307338627 -6.63230764534067 1.41437063426186e-10 LSM3 essential 8.03044298723354e-20 2.16257269978639e-06 0.0149434717950916 4.94066217277694 -6.63230764534067 0.000414233813287391 98.9034829658189 37.4496838090725 2.64096977347133 0.00867384638672105 -67.0834019389617 69.4862947675351 -0.96541918321286 0.33506620271472 KIAA0232 other 1 1 1 2.64096977347133 -0.96541918321286 6.07114775410204e-09 633.449582364592 100.031495107656 6.33250139551411 8.27698039401137e-10 66.3454583725818 587.694032021539 0.112891155529295 0.910188530572601 MTSS1 other 7.11963497123546e-05 1 1.10414918456112e-05 6.33250139551411 0.112891155529295 1.17451128613963e-12 677.475999656922 102.111530233145 6.63466699705782 1.39463544499456e-10 -66.5485307487772 164.350093255323 -0.404919336707598 0.685808196289486 TMEM43 other 1.54459979240223e-08 1 1.88959156442313e-06 6.63466699705782 -0.404919336707598 1.68947626036602e-21 182.579555879594 17.2834853412948 10.5638158203752 1.50674685295724e-22 44.6395223278223 101.701792658274 0.438925619313464 0.661014445831811 RNF139 other 2.47660325007055e-17 1 2.25725746041525e-18 10.5638158203752 0.438925619313464 0.431369439618717 341.999082842438 729.014741119246 0.469125058181089 0.639301713801497 -1869.35340060813 1798.41895642231 -1.03944266931379 0.29938857520023 RPS9 other 1 1 1 0.469125058181089 -1.03944266931379 0.000460984229635455 2.34600262776584 3.07541826073553 0.762823924705695 0.446130364057764 20.6893682668486 5.68070555934966 3.64204200529224 0.000315391443391418 CYTL1 other 1 1 1 0.762823924705695 3.64204200529224 1.36572824085685e-06 164.508679442249 46.8924764836192 3.50821052284829 0.000516139629893387 -334.491666873794 115.679853732798 -2.89152913044319 0.00409776279085185 TSEN34 essential 0.0140069088382278 1 1 3.50821052284829 -2.89152913044319 3.49752451033329e-09 388.741101111355 63.1540556553353 6.15544159559473 2.25351560338425e-09 -6.83578218106977 169.822047043061 -0.0402526191392362 0.967916987204286 GSTA4 other 4.14351728739184e-05 1 2.97103497150179e-05 6.15544159559473 -0.0402526191392362 2.5551307845426e-12 80.2695422647391 15.9955164293157 5.01825262219264 8.70742593692308e-07 -41.2210600089195 30.8621331506582 -1.33565168057868 0.182621319163863 MSANTD4 other 3.33393464767119e-08 1 0.0104097277075915 5.01825262219264 -1.33565168057868 0.0013713256937033 102.694371198838 47.0131531666064 2.18437531375331 0.0296669759631513 -257.133807736561 114.333381009289 -2.24898280333082 0.0251998723173782 NDUFA3 other 1 1 1 2.18437531375331 -2.24898280333082 0.801177307500012 6.55807387266448 10.3270371643617 0.635039243907843 0.525860910834942 9.16418963344474 25.1147816149616 0.364892268383707 0.715435140376352 OSCAR other 1 1 1 0.635039243907843 0.364892268383707 0.976111655108531 -1.69952150081855 14.7258759088969 -0.115410554274178 0.908192555387418 5.72420500424617 39.4767163124234 0.145002055362055 0.884801108517099 PAQR8 other 1 1 1 -0.115410554274178 0.145002055362055 0.636302047649504 5.21726742227542 6.22519388762601 0.838089144925418 0.402608146454905 -1.44597754026873 11.2322631211742 -0.128734300885712 0.89764901726485 NUDT6 other 1 1 1 0.838089144925418 -0.128734300885712 1.20470291320385e-07 415.236184071272 78.2559215191771 5.3061311656718 2.10353197088022e-07 -300.015188862591 181.603855359143 -1.65203094542941 0.0995152651366636 TANC2 other 0.00132300473928047 1 0.00258587185180305 5.3061311656718 -1.65203094542941 0.674460237481301 1.59117060747302 3.32148133504839 0.479054508204799 0.632230137151196 -4.45905605096445 7.94088878036876 -0.561531104929715 0.574832293447631 PKHD1 other 1 1 1 0.479054508204799 -0.561531104929715 2.0239165487625e-12 30.9015761694038 6.19765673056878 4.98600963441353 1.01523387246252e-06 -42.1244081849514 13.6955348273126 -3.07577679266267 0.00228180258504607 DNAJC24 other 2.64728284578135e-08 1 0.0121005725258807 4.98600963441353 -3.07577679266267 0.548732293606929 16.0190797235897 15.8877747472193 1.0082645290772 0.314094056529614 -11.0839563113434 51.4409959712222 -0.215469317848047 0.829539561240635 ZNF160 other 1 1 1 1.0082645290772 -0.215469317848047 0.601938231866726 -1.13414707028402 3.62827764098583 -0.312585524732848 0.754800460556761 -11.6202712297133 11.5824042182097 -1.00326935675791 0.316493713038823 ZNF415 other 1 1 1 -0.312585524732848 -1.00326935675791 0.000550903906527561 182.545556248961 48.8899342052856 3.73380654354053 0.000223201118133655 77.2364345625785 96.0519419331959 0.804111119547135 0.421929755377663 CAVIN3 other 1 1 1 3.73380654354053 0.804111119547135 0.41338503462311 -2.85657575013454 2.6350004564389 -1.08408928095409 0.279149037439733 -7.20925932000093 7.00561855098708 -1.02906820683024 0.304232161733558 CEACAM3 other 1 1 1 -1.08408928095409 -1.02906820683024 0.171515167874084 41.4647874210357 23.5834576203809 1.7582149355912 0.0796698941504072 -74.8090443045654 132.048895588442 -0.566525331175229 0.571435079001793 HAS2 other 1 1 1 1.7582149355912 -0.566525331175229 0.0344525466145121 14.2228928903266 5.45046742856898 2.60948131086453 0.00950788454919074 24.5053528928623 29.4359170386986 0.832498367917185 0.405768573474632 PDGFD other 1 1 1 2.60948131086453 0.832498367917185 0.421362743880873 -3.64442292989054 22.3301742474759 -0.163206202043071 0.870459104173899 53.0119022803474 45.8786466966464 1.15548095023087 0.248755554688806 S1PR1 other 1 1 1 -0.163206202043071 1.15548095023087 0.700421687835302 12.4899629893722 15.428188542404 0.809554728673678 0.41879957001586 15.893163786176 30.4606489116893 0.521760512464888 0.602199160330685 PYGO1 other 1 1 1 0.809554728673678 0.521760512464888 3.49026398601031e-05 328.317773227116 89.9689665193666 3.64923357385064 0.000307182618745179 -170.032307067074 167.63774515185 -1.01428414533406 0.311215863331402 LRRC8E other 0.316532040891275 1 1 3.64923357385064 -1.01428414533406 0.771975465313059 17.7676391637815 47.9209935852525 0.370769423471416 0.71105691760658 -133.432864360698 230.15018969678 -0.579764303199117 0.562485387476662 PKIA other 1 1 1 0.370769423471416 -0.579764303199117 5.86302958598053e-14 0.468680033941857 2.1474917250664 0.218245327081465 0.827377518026398 -25.4241168594388 4.1405533627781 -6.14027030492865 2.44675965496879e-09 XKR6 other 7.91391733515651e-10 3.72935106610343e-05 1 0.218245327081465 -6.14027030492865 2.18019070780025e-08 59.1854555130063 9.6910959718655 6.10719940085511 2.93720048718499e-09 32.6758741404678 49.0935195788813 0.665584264904163 0.506156329535061 TSNARE1 other 0.000249108590273256 1 3.85977516020979e-05 6.10719940085511 0.665584264904163 0.330576773352026 -7.38761231536889 5.97683620510782 -1.23604061778628 0.217352838514193 -15.7353881546834 14.5003321614844 -1.08517432424614 0.278663856316822 FPR2 other 1 1 1 -1.23604061778628 -1.08517432424614 0.142024945950687 -15.5465622909623 13.6857632481397 -1.13596604070113 0.256823475325005 -60.9132301628913 33.202869573683 -1.83457728036771 0.0674995068614948 FPR1 other 1 1 1 -1.13596604070113 -1.83457728036771 2.19800773301345e-08 115.953706538895 20.1660357611928 5.74995045689814 2.08421241539529e-08 -73.0374444289907 69.1051893485284 -1.05690245721823 0.291353331443336 FEZ2 other 0.000251078423342126 1 0.000266612452177365 5.74995045689814 -1.05690245721823 3.90865201031741e-07 274.140790989152 64.4176747287298 4.25567660030558 2.74331132494709e-05 -1.46412904053625 124.202955758603 -0.0117881980472501 0.990601965399028 SOX7 other 0.00416505958219423 1 0.298532006276553 4.25567660030558 -0.0117881980472501 5.37197156753497e-13 232.407111946109 32.886616303378 7.06692077415811 1.1194085775271e-11 -241.765498532716 156.633204928183 -1.54351370543409 0.123763870397158 C11orf24 other 7.11786232698383e-09 1 1.54747041757346e-07 7.06692077415811 -1.54351370543409 8.03384292924833e-06 80.2441064033132 16.3452892779273 4.90931087476529 1.45936467099289e-06 28.1229315654374 65.311520179609 0.43059679958602 0.667051443305984 FAM86JP other 0.0773337720369444 1 0.017249690411136 4.90931087476529 0.43059679958602 4.87133161084705e-06 35.2690468438562 9.99537178100323 3.52853776893892 0.000479059537929332 -61.4007918674027 19.5244572575749 -3.14481427357379 0.00181784351251829 KYAT1 other 0.0478023770972421 1 1 3.52853776893892 -3.14481427357379 2.16829966082348e-07 49.2799655079836 9.46635679734941 5.20580055906851 3.46152532829588e-07 -49.4323765363281 33.0288001278611 -1.49664463574109 0.135471382471519 TRMT61B other 0.00234891902257007 1 0.00421267632453609 5.20580055906851 -1.49664463574109 0.0041221819756985 111.610731062381 75.0443146918196 1.48726431203652 0.137929680287447 -274.06000890959 135.037723752376 -2.02950702436413 0.0432339006698811 INSR other 1 1 1 1.48726431203652 -2.02950702436413 8.33134175437856e-26 287.531578195668 24.3800924919423 11.7937033377005 9.04793126279409e-27 49.6486265174958 163.619848317885 0.303438898323858 0.761758950175506 MFN1 other 1.24595215936731e-21 1 1.36768528968395e-22 11.7937033377005 0.303438898323858 0.222616992994244 -14.9484098238128 11.8894634899575 -1.25728211676154 0.209568329834339 -44.1783854628912 26.4537145996465 -1.67002578395858 0.0958920835528481 GIMAP8 other 1 1 1 -1.25728211676154 -1.67002578395858 0.0642318244727856 -0.15438451834328 6.49281081369385 -0.0237777632481869 0.981044790740314 -25.131987566419 11.8457118503768 -2.12161057806075 0.0346435537627221 NRTN other 1 1 1 -0.0237777632481869 -2.12161057806075 3.42661474162046e-25 57.9424684767451 5.00072187439065 11.586820849501 4.90618556542115e-26 21.8741411072554 33.4514109125625 0.653907877441447 0.513655928291534 KCNMB3 other 5.11250919449773e-21 1 7.40637772955977e-22 11.586820849501 0.653907877441447 0.145380534355697 -2.32346235275015 104.095530086878 -0.0223204814924423 0.982206309959035 -335.586321318061 188.752768031053 -1.77791470196003 0.076373386081522 FUT3 other 1 1 1 -0.0223204814924423 -1.77791470196003 0.186923087032409 5.20014545559285 2.88792035047735 1.80065404322294 0.0727018800314958 -0.895620010465129 10.250607230119 -0.087372385884961 0.930430338024908 KCNG3 other 1 1 1 1.80065404322294 -0.087372385884961 0.00441850378699134 -35.753846067146 33.8684082782963 -1.05566951282024 0.291920586528134 -246.117250683432 75.7626916498348 -3.24852833662449 0.00128402630341933 ATP6V0E2 other 1 1 1 -1.05566951282024 -3.24852833662449 0.0438903794934499 28.9721496628171 11.8961608460995 2.43542013575887 0.0154236696009105 -11.2974719388455 43.2899678627151 -0.260972056497547 0.794282980673851 PRKCE other 1 1 1 2.43542013575887 -0.260972056497547 7.11502806502746e-38 300.39865527476 26.4489240499717 11.3576890578686 2.40770975630987e-25 -182.827175252542 46.2089838976382 -3.95652879226991 9.37039036135923e-05 JAGN1 other 1.08532638103929e-33 1 3.62986322861276e-21 11.3576890578686 -3.95652879226991 4.97919888042379e-33 508.277683988579 56.1309525568009 9.05521215721816 1.38960096214878e-17 -490.419960506788 95.603046638242 -5.12975242685013 5.0466610833136e-07 TADA3 essential 7.55444054137898e-29 0.00758815960487033 2.03618228983661e-13 9.05521215721816 -5.12975242685013 5.97087441381299e-09 113.561237299082 18.7160266661754 6.06759326242659 3.66582804268134e-09 -62.2873068141506 68.1314416793682 -0.914222644917445 0.361288199079904 SOCS5 other 7.00562694972678e-05 1 4.80333448432535e-05 6.06759326242659 -0.914222644917445 0.0058162407010885 154.266512458514 59.7021152226517 2.583937133269 0.0102122786304705 -190.404987253906 116.711591806578 -1.63141453480866 0.103789676970627 C9orf16 other 1 1 1 2.583937133269 -1.63141453480866 0.0116879441662017 1.12017112472595 6.72788346594808 0.166496808453281 0.86787114673141 -31.8345768205285 12.3219917351183 -2.5835577157383 0.010221880997923 MORN4 other 1 1 1 0.166496808453281 -2.5835577157383 0.0444018291005398 81.0493492221012 35.6883736506415 2.27102949592225 0.0238219769001857 -87.005680261787 106.479630036154 -0.817111030835151 0.414484509865659 ZNF672 other 1 1 1 2.27102949592225 -0.817111030835151 0.0215791898741749 59.8697558455193 21.7131869356498 2.75729933256468 0.00616924722110743 45.0726263214444 64.7833418929773 0.695744075628343 0.487103726949976 ZNF692 other 1 1 1 2.75729933256468 0.695744075628343 0.9543361906498 2.27924742671228 7.47039985201628 0.305103805935783 0.760486065937499 0.232289969815746 14.6011122291981 0.0159090599516954 0.987316887422866 NAIF1 other 1 1 1 0.305103805935783 0.0159090599516954 0.289275953356888 5.13063890541343 3.39783100715639 1.50997471463632 0.132036638253669 7.75551695419395 12.05060447394 0.643579081112951 0.520309372361502 RBKS other 1 1 1 1.50997471463632 0.643579081112951 0.428022024448832 6313.53115659059 5402.83023248839 1.16855997410875 0.243456237180132 -1559.55659636922 11558.0776947696 -0.134932177958535 0.892750862365347 MUC7 other 1 1 1 1.16855997410875 -0.134932177958535 0.182036940795576 6438.43425507642 3616.14162111389 1.78047071427838 0.0759536036188599 1150.16977076196 7735.87990249963 0.148679889716271 0.881900468673321 SMR3B other 1 1 1 1.78047071427838 0.148679889716271 2.78015274604054e-29 74.6369260508021 9.11225443050747 8.19082990054806 6.50052600583138e-15 -83.517011923267 22.922817205563 -3.64340086012634 0.000314392249135556 TMEM126A other 4.19525049377518e-25 1 9.35685713279369e-11 8.19082990054806 -3.64340086012634 1.82118733966378e-20 73.4024212362379 12.3981360170272 5.92044006739636 8.38910111670816e-09 -116.967565326963 31.2257786354469 -3.7458654495867 0.000213738340667225 TMEM126B other 2.65128452908253e-16 1 0.000108630470360254 5.92044006739636 -3.7458654495867 7.68582731368279e-05 139.432736828365 129.228252829287 1.07896480665539 0.281416018093073 -800.633362460614 237.41995709736 -3.37222435825938 0.000837105888831686 TRIM8 other 0.67043471657255 1 1 1.07896480665539 -3.37222435825938 9.83026739334221e-07 215.138012747622 48.4124254449865 4.44385941770453 1.23542474881772e-05 -87.3809834446696 130.299485691929 -0.670616487706383 0.502969055261441 NETO2 other 0.0101861230729812 1 0.137749859493176 4.44385941770453 -0.670616487706383 0.229685446885132 117.384960013057 80.7713485023111 1.45329949529935 0.147123634658028 -60.9721723518854 173.663442915151 -0.351093882099731 0.725749678455716 CSN3 other 1 1 1 1.45329949529935 -0.351093882099731 0.320457145139336 4.90214933166633 6.20680017887997 0.789802988719855 0.430229511306834 -14.8120056091659 13.6765850854737 -1.08301930025633 0.279617786302614 CLDN20 other 1 1 1 0.789802988719855 -1.08301930025633 2.5162979247521e-05 132.545985676675 46.4094380410733 2.85601358842935 0.00457401127088058 -542.715708371432 189.38835458253 -2.86562344114422 0.00444090379757193 CDC42BPG other 0.231574898014936 1 1 2.85601358842935 -2.86562344114422 2.46057958807306e-06 307.464720777116 61.2264508663623 5.02176292152247 8.58790435886378e-07 -107.264909830358 334.810519718204 -0.320374968864893 0.74889651395963 SCAND1 other 0.0247017584846654 1 0.0102711336132011 5.02176292152247 -0.320374968864893 1.51812112513445e-14 2547.49940141735 333.083626177801 7.64822765577042 2.49412928704811e-13 -2052.09148428444 1102.13121700578 -1.86193027891858 0.0635439932987777 JUNB other 2.07071721468339e-10 1 3.52744705067214e-09 7.64822765577042 -1.86193027891858 0.857434653735535 1.1258134360065 23.4957214913551 0.0479156784532334 0.96181380900144 41.3400072492119 74.6612344096109 0.55370109503427 0.580176236574474 TMEM37 other 1 1 1 0.0479156784532334 0.55370109503427 0.58335142047294 -62.9859660847049 85.8237454156555 -0.733899059982243 0.463547625865283 -157.805811074469 159.219164055758 -0.991123223201988 0.322374248983651 LRG1 other 1 1 1 -0.733899059982243 -0.991123223201988 1.9466229288668e-08 93.2027571206655 24.1846665521553 3.85379541701226 0.000141820470731323 -164.62286142615 65.3767915758961 -2.51806271702764 0.0123120475149768 SHCBP1 other 0.000223121920106712 1 1 3.85379541701226 -2.51806271702764 0.501111136551786 58.863573202123 52.8800364578039 1.1131530374245 0.266480795989229 -39.4547483997359 225.019979218946 -0.175338867849357 0.860924614414048 SOSTDC1 other 1 1 1 1.1131530374245 -0.175338867849357 0.715964061786081 22.0487341592718 66.71464049299 0.33049318704773 0.741244293675476 -99.8512743458171 153.742650982951 -0.649470226429816 0.516501843729331 NPTX1 other 1 1 1 0.33049318704773 -0.649470226429816 1.27444012423048e-06 42.6746516382829 31.0709502698647 1.37345820670546 0.170574433857261 -267.721100375101 62.6265889767595 -4.27487916473386 2.52897921863405e-05 FAM98B essential 0.0130948722764682 0.36826995381749 1 1.37345820670546 -4.27487916473386 0.053085575680449 12.7051742043819 5.71041941324538 2.2249108664264 0.0268044057751098 -3.2374126839643 12.2011248850147 -0.26533723033525 0.790925475801873 ZNF439 other 1 1 1 2.2249108664264 -0.26533723033525 0.0172711207516902 -8.30789635413394 23.7836041745852 -0.349311916442489 0.727091551418209 -143.19797089295 50.8170597901758 -2.8179113763019 0.00514322881259205 ZNF440 other 1 1 1 -0.349311916442489 -2.8179113763019 0.252567563920688 252.929448817997 155.539957755775 1.6261380835344 0.104904622978015 12.991360962996 358.577808659143 0.0362302425004367 0.971121361747304 GAA other 1 1 1 1.6261380835344 0.0362302425004367 1.02997371073988e-14 343.223454879817 48.6226481124362 7.05892147392175 1.05255126046312e-11 -361.491938599087 114.312452964652 -3.16231459673838 0.00171566549240445 CANT1 other 1.41065199422933e-10 1 1.45609941372468e-07 7.05892147392175 -3.16231459673838 0.988430114748893 -1.03906935532276 9.74538347359909 -0.106621700227361 0.915155912931571 3.1582496105642 33.90545918261 0.0931487048606043 0.925843715978751 KCNK3 other 1 1 1 -0.106621700227361 0.0931487048606043 1.66575746700107e-10 116.678143737981 28.5202875725706 4.09105775813413 5.4396148229461e-05 -161.862566705527 52.2343690301851 -3.09877518788426 0.00211561734422593 ZDHHC16 other 2.07036995573563e-06 1 0.578122263382712 4.09105775813413 -3.09877518788426 0.0110705163089026 215.601001121817 77.2650818673469 2.79040668709797 0.00558002554504886 -143.695158657024 196.071952940175 -0.732869523163612 0.464174503568171 CHST11 other 1 1 1 2.79040668709797 -0.732869523163612 2.48448865710876e-09 33.722281332287 19.0519556686734 1.77001678561197 0.0776765239374309 -164.902702947337 34.89329764337 -4.72591340127092 3.43681240043091e-06 EXOSC1 essential 2.96126203040793e-05 0.0511088372068081 1 1.77001678561197 -4.72591340127092 9.27100856136358e-08 452.897314720407 206.480753003486 2.1934117738943 0.0289968328895377 -1431.90340965712 378.165606590428 -3.78644536865021 0.000182475067445569 PGAM1 essential 0.00102565167714365 1 1 2.1934117738943 -3.78644536865021 4.18396448657713e-05 121.694503511825 26.9042778568539 4.52323991594604 8.66483502376731e-06 9.09392403781539 125.261604823188 0.0725994533652336 0.942171379827205 CHD7 other 0.376556803791942 1 0.0977566687381428 4.52323991594604 0.0725994533652336 9.54795177185375e-15 60.6792877917649 19.8210123683874 3.06136168344976 0.0023900265168991 -155.686404732876 36.3663329377726 -4.28105866487213 2.46139303955268e-05 ESCO2 other 1.30835583129712e-10 0.358526510141243 1 3.06136168344976 -4.28105866487213 0.739084493439815 -1755.82923205373 2760.81091540697 -0.635983153447835 0.525243414909968 -3972.48602290235 8032.93934552076 -0.494524588327366 0.621276135595626 KRT19 other 1 1 1 -0.635983153447835 -0.494524588327366 0.92939875039964 -0.54561469649157 3.40239581994906 -0.160361911242807 0.872697173141369 -3.20125759818297 8.63435438251434 -0.370758189479218 0.711062956832905 LURAP1 other 1 1 1 -0.160361911242807 -0.370758189479218 0.622543229692121 -55.7070169430964 70.9650582481693 -0.78499219641708 0.433040732329707 -131.487585130232 207.012887548798 -0.635166180652577 0.525775364201593 KRT38 other 1 1 1 -0.78499219641708 -0.635166180652577 0.000247607379187352 153.600673765623 37.2021052819415 4.12881670544016 4.6607314183517e-05 106.962668275975 222.501695040111 0.48072743111774 0.631039759630069 TPPP other 1 1 0.49893129833455 4.12881670544016 0.48072743111774 0.0756992228246436 -10.9934132171077 30.8009219866133 -0.356918316337597 0.721388203207024 -122.580734691671 56.4456338248293 -2.17166016900585 0.0306155292557974 KCND3 other 1 1 1 -0.356918316337597 -2.17166016900585 0.724296768488067 3267.1859437811 15689.9413268943 0.20823442712184 0.835178816416244 -34695.7478596739 45769.2861773335 -0.758057438895701 0.44897624832833 KRT13 other 1 1 1 0.20823442712184 -0.758057438895701 0.495473186034741 55.562245015816 47.8197838557127 1.16190916260652 0.246140953626066 -18.7227746750174 124.712722002024 -0.150127223385546 0.880759119173594 KRT9 other 1 1 1 1.16190916260652 -0.150127223385546 0.284496481974424 -2.75884708591851 8.34454389459015 -0.330616882212951 0.741151617121654 -30.8621604529269 19.427951689673 -1.58854422462517 0.113157046939268 PDE7B other 1 1 1 -0.330616882212951 -1.58854422462517 1.16939453782059e-16 175.168612671203 19.5668971986057 8.95229380996006 2.97058323019921e-17 -59.3170601849976 114.778590822395 -0.516795508291117 0.605658139271456 MRPL36 other 1.64159605219255e-12 1 4.34477503248937e-13 8.95229380996006 -0.516795508291117 0.000100093707815241 84.5694160429826 22.8341646693036 3.70363520048846 0.000250264069836975 -78.166413944925 63.20259833853 -1.23675950039656 0.217083273637654 ZNF581 other 0.862507480243933 1 1 3.70363520048846 -1.23675950039656 1.3348216443183e-13 2.90840316798082 6.44720581085817 0.451110644410107 0.652216303700038 -71.7096385132682 11.9845123230169 -5.98352578565473 5.86334904707953e-09 NAT1 other 1.78959537853754e-09 8.92108557513151e-05 1 0.451110644410107 -5.98352578565473 0.00115235285663872 43.2001233692317 11.8697037951863 3.63952834162141 0.000318510425050208 -16.4687319873685 34.615649777351 -0.475759724092886 0.634571203028572 KRT20 other 1 1 1 3.63952834162141 -0.475759724092886 0.878075174364919 0.718159997764317 3.0997596011695 0.231682481923232 0.816933183102639 -3.50940691465412 8.41701798702201 -0.416941833802089 0.677001385707437 KSR2 other 1 1 1 0.231682481923232 -0.416941833802089 0.0158094833991081 31.1215346866849 20.1258894308738 1.54634332030779 0.123010034591178 -108.362405690379 54.6855594984329 -1.98155430216425 0.0483846408186399 ZNF524 other 1 1 1 1.54634332030779 -1.98155430216425 6.01916975507974e-06 485.878095233651 113.010369901206 4.29941159964706 2.27640585613924e-05 -116.071185562983 162.144838584864 -0.71584878418583 0.474606752132333 MCC other 0.0585905983959462 1 0.249129856895879 4.29941159964706 -0.71584878418583 0.810023086604558 -1.69741312004959 3.27155707461939 -0.51883952544128 0.604232385902968 -4.09711410504519 9.54085088185325 -0.429428586169178 0.667901248155485 KRT27 other 1 1 1 -0.51883952544128 -0.429428586169178 0.0139742955727567 20.0382956429962 7.25429390552677 2.76226685931897 0.00607195867885047 -9.3645752522831 14.4980440332424 -0.645919906906833 0.518794144459494 ZBTB26 other 1 1 1 2.76226685931897 -0.645919906906833 0.0809562983038092 51.3885981812127 26.4690060307361 1.94146308786736 0.0530824605933898 15.4965769931876 39.933404657342 0.388060500379561 0.698230093038886 DSEL other 1 1 1 1.94146308786736 0.388060500379561 3.97345104528884e-14 150.988944258026 20.6895495246682 7.29783623746868 2.36716505955069e-12 -87.389035658837 57.142690254399 -1.5293125904605 0.127184194682779 POLR1C essential 5.37568191917127e-10 1 3.30692958819231e-08 7.29783623746868 -1.5293125904605 1.98862539228992e-14 288.549873237845 34.982343992154 8.24844308038828 4.54193092793575e-15 -73.697856231646 218.617483934502 -0.337108701945018 0.736261616832618 ASXL1 ts 2.70691688398504e-10 1 6.54810181880498e-11 8.24844308038828 -0.337108701945018 0.00144734801482575 138.593978815045 38.4173712691188 3.60758621000318 0.000358957477239902 54.3794028897681 106.105352569522 0.512503861236763 0.608655324385345 DLK2 other 1 1 1 3.60758621000318 0.512503861236763 0.00020182201132066 77.3964839945456 31.7566151601074 2.43717674583188 0.0153468983783299 -164.622954678268 69.8656732200055 -2.35627808465931 0.0190616554522066 ZNF562 other 1 1 1 2.43717674583188 -2.35627808465931 8.61069397791786e-05 150.109915109932 37.1069344387908 4.04533323434583 6.5684466191334e-05 -44.858066434617 102.486042936699 -0.437699272498243 0.661902366301437 ZNF318 other 0.746891595644595 1 0.693562278514296 4.04533323434583 -0.437699272498243 0.000141426541910047 102.477351308357 28.0231739624744 3.65687881913674 0.000298385172886899 -50.3968837250827 61.6519709288495 -0.817441567005929 0.414284329688899 ZNF561 other 1 1 1 3.65687881913674 -0.817441567005929 2.82413159942765e-19 383.96632615034 42.393625344781 9.05717128524864 1.42253959177159e-17 -404.669513558542 122.596118104787 -3.30083464153944 0.00107425774964599 WIPF2 other 4.07380983217438e-15 1 2.08416275590455e-13 9.05717128524864 -3.30083464153944 0.0171571188228177 461.034270531054 301.675295336806 1.52824668661161 0.127454807466527 -1063.17860950778 641.267766469371 -1.6579324037466 0.0983265761931048 HOPX other 1 1 1 1.52824668661161 -1.6579324037466 0.000260567374505022 215.576343315694 57.8844284462983 3.72425450336255 0.000231572992315477 -56.7646602070066 123.727768155181 -0.458786746527356 0.646699740967545 LRRC8C other 1 1 1 3.72425450336255 -0.458786746527356 1.04555244979157e-06 515.446104941307 106.795918981564 4.82645881843378 2.1557899266326e-06 -375.84843382744 346.5238186195 -1.08462510694002 0.278904200701061 RSL1D1 essential 0.0108110123308448 1 0.0252205863516748 4.82645881843378 -1.08462510694002 0.0463402164189785 158.758053360909 76.3616177502724 2.07902946582535 0.0384133371091413 -102.577338322636 163.222697201296 -0.628450209936985 0.530158747616181 LRRC8D other 1 1 1 2.07902946582535 -0.628450209936985 3.92200191743416e-06 91.3092434315833 26.5638725758203 3.43734683905604 0.000665841199032265 -89.0113362890256 45.4962529496978 -1.95645422464658 0.0512894035111156 PPID other 0.0387689889538367 1 1 3.43734683905604 -1.95645422464658 0.316031187804293 8.62617959311149 6.35898714028082 1.35653358039824 0.175885712320779 14.4571016565874 13.5127855913393 1.06988315317113 0.28547823518017 COL24A1 other 1 1 1 1.35653358039824 1.06988315317113 7.21071375668773e-06 76.725589656386 25.424379816562 3.01779591911246 0.00275259641441429 -100.045369046564 43.5446304721546 -2.29753629693883 0.0222393022831567 ETFDH other 0.0696915484583869 1 1 3.01779591911246 -2.29753629693883 0.0326614202266966 4.93924337318441 7.38530051380185 0.668793824158383 0.504113737543801 32.7447309589047 12.6488899284703 2.58874345053809 0.0100766045182683 RXFP1 other 1 1 1 0.668793824158383 2.58874345053809 2.50126607091238e-05 160.324738409 61.5455259731987 2.60497795532395 0.00961837415837565 -373.525199482416 130.36116209784 -2.86531044577583 0.00444251583267972 LPAR3 other 0.230241541827485 1 1 2.60497795532395 -2.86531044577583 0.2763412422332 23.4113497556464 14.5807102362602 1.60563850294656 0.109358547643431 20.6981351004748 103.030156263399 0.200893950384386 0.840911562403065 PTGER4 other 1 1 1 1.60563850294656 0.200893950384386 4.67907798450679e-08 216.736807499821 71.6464825254638 3.02508650613505 0.0026869929922478 -346.287506783705 98.5092020540575 -3.51528080182477 0.000502677977054751 TBCA essential 0.000524898968301971 1 1 3.02508650613505 -3.51528080182477 0.767163841125488 -0.834620730581722 1.17258331178024 -0.711779472039887 0.4771298198641 -0.567503231667057 2.93682951511015 -0.193236695813367 0.846898533469628 NEUROD2 other 1 1 1 -0.711779472039887 -0.193236695813367 0.0555676942165097 15.1512718142046 7.84795122773446 1.93060218833425 0.0544295901164544 -8.69220496483988 24.3978226574391 -0.356269700246778 0.721877099810796 MAP6 other 1 1 1 1.93060218833425 -0.356269700246778 0.975639674982428 1.97690552978256 14.5420658960341 0.135943925981088 0.891951625812668 -2.38354602161536 25.0755514390233 -0.0950545804510611 0.924331342643559 ECEL1 other 1 1 1 0.135943925981088 -0.0950545804510611 1.78677650683058e-09 436.166834646967 72.285978353091 6.03390650004693 4.60280327739865e-09 -807.607255022868 447.002031767277 -1.8067194277169 0.071785062888335 BCL2L1 essential 2.13859280102553e-05 1 6.01218164093812e-05 6.03390650004693 -1.8067194277169 9.27086730067643e-11 130.784689043384 41.4708993332235 3.15364969523601 0.0017658159360394 -308.411383736142 70.9292543429684 -4.34815488465257 1.8490781522967e-05 PLRG1 other 1.16043446002567e-06 0.270372207428823 1 3.15364969523601 -4.34815488465257 1.78112818425105e-13 58.3779295939863 8.80467815585395 6.63033089462477 1.46812029144068e-10 -51.2449416624774 22.4734240906964 -2.28024627914586 0.023265274603024 ZNF584 other 2.38297139770948e-09 1 1.9885689347564e-06 6.63033089462477 -2.28024627914586 0.203251191710486 7.00276607767822 7.83233123320015 0.894084515730704 0.371954976218542 -14.021259621914 12.8378494205935 -1.09218134303882 0.275582755106101 DSCAM other 1 1 1 0.894084515730704 -1.09218134303882 5.45869457259878e-08 3471.26757624436 646.770086784557 5.36708120423735 1.5424033915839e-07 -1360.77030287912 1463.02145210204 -0.930109603604234 0.353017651190866 CLSTN1 other 0.0006106095748909 1 0.00190671907267601 5.36708120423735 -0.930109603604234 0.00391291257088251 99.0948297305304 50.8445257756755 1.94897736223824 0.0521716802820344 -143.937417826473 74.6566251779605 -1.92799255904438 0.0547406957496515 CXXC5 other 1 1 1 1.94897736223824 -1.92799255904438 0.00143912366664272 71.7977750722559 21.6387638585239 3.31801647920721 0.00101206250815923 -27.9610184105788 55.6688692309092 -0.502273870421171 0.615823599559865 ZNF274 other 1 1 1 3.31801647920721 -0.502273870421171 7.48774878546276e-07 340.981041684975 70.5976357236393 4.82992154326209 2.12114574694573e-06 -163.07786665228 159.758017194474 -1.02078048736524 0.308129543916097 PIK3CD other 0.00781870728178021 1 0.024821647530759 4.82992154326209 -1.02078048736524 0.0183400000987597 24.8779068502782 10.9719422142675 2.2674113994082 0.0240317442721979 -25.1010823006132 24.8288163612934 -1.01096572367196 0.312796637786537 SLC25A33 other 1 1 1 2.2674113994082 -1.01096572367196 0.0334752025238991 28.9089999254055 75.3064713269913 0.383884670414028 0.701318870572599 -230.711188054802 103.587518457404 -2.22721029995205 0.0266285343378566 ENC1 other 1 1 1 0.383884670414028 -2.22721029995205 0.00511992685786602 243.463835869201 74.9308979030102 3.24917814523373 0.00128039488579794 88.5888780321436 169.563917444024 0.522451234717363 0.601717686532891 SPSB1 other 1 1 1 3.24917814523373 0.522451234717363 0.000123352452579124 50.3925959152038 13.3566776813003 3.77283910846742 0.0001932193403794 -15.9671597720958 49.1928297291702 -0.324583071557431 0.745714853430896 P2RY6 other 1 1 1 3.77283910846742 -0.324583071557431 0.000166749640328341 218.745171607496 61.9724230581033 3.52971791021319 0.000477408848884255 -268.656344236298 145.603784293106 -1.84511924288645 0.0659498425798468 BPTF other 1 1 1 3.52971791021319 -1.84511924288645 0.712333743068772 -4.42134714189494 5.57452177830419 -0.793134786754738 0.428286964692247 -6.49901334283343 14.4862655439854 -0.44863276343376 0.654000232310041 ZIK1 other 1 1 1 -0.793134786754738 -0.44863276343376 0.000509668995564913 149.354226746765 38.2752296257559 3.90211184118574 0.000116485476717604 72.5597785122438 237.324341922923 0.305740986888776 0.760002542293322 NMRAL2P other 1 1 1 3.90211184118574 0.305740986888776 4.49553529071596e-07 318.79370246972 71.7681722703523 4.44199277179328 1.23055090941525e-05 -269.808438984078 157.636589607232 -1.71158510632801 0.0879451280178094 PLEKHG5 other 0.00476796472933335 1 0.137218731908894 4.44199277179328 -1.71158510632801 0.000163709748475262 230.892249089631 63.9075073717804 3.61291276385451 0.000351464833436685 -336.269546619516 247.20016374858 -1.36031279882778 0.174688419002206 ATF7IP other 1 1 1 3.61291276385451 -1.36031279882778 0.000962697252330707 28.9326290332844 11.2240027120871 2.57774608358985 0.0103974633665711 -108.917766490477 51.4567829964863 -2.11668433485075 0.0350679783948093 RGS19 other 1 1 1 2.57774608358985 -2.11668433485075 0.0554238649342128 64.2770063005152 28.6772898186549 2.24139054656072 0.025694731687714 -51.1696374666527 131.471910420759 -0.389205856238726 0.697386016033911 TCEA2 other 1 1 1 2.24139054656072 -0.389205856238726 0.00537162364699363 -191.54315964881 187.95441054266 -1.01909372116243 0.308930731554794 -1102.4960732107 364.092494992424 -3.02806591284899 0.00266202198270519 DEFB4A other 1 1 1 -1.01909372116243 -3.02806591284899 0.39551853545069 20.3478556131045 18.0356148221939 1.12820415681451 0.260081501202576 45.0933587747907 37.8869391700328 1.1902085458109 0.234849428658385 ANO5 other 1 1 1 1.12820415681451 1.1902085458109 2.51754072548034e-16 244.103935244116 48.0145890089951 5.08395344586591 6.3132339582161e-07 -360.147647827244 68.4617359139913 -5.26056844774865 2.63927716498543e-07 HDAC3 essential 3.52354999938229e-12 0.00397791854306605 0.00759608309852562 5.08395344586591 -5.26056844774865 9.92423273315775e-09 91.4079288020263 14.9230140820457 6.12529937313413 2.67857736570506e-09 13.488570955295 48.9208304454108 0.275722444457406 0.782940904179153 GPHN other 0.000115220342031961 1 3.52447209779471e-05 6.12529937313413 0.275722444457406 0.926265887624196 -1.2715964470995 5.31995355636702 -0.239023975233323 0.811240962943151 -5.22770594246187 13.5936075979987 -0.384570902519762 0.700812408999047 VAT1L other 1 1 1 -0.239023975233323 -0.384570902519762 4.5405886039041e-07 112.710206805994 31.1008424981047 3.62402423062536 0.000337269703128656 -177.972419761568 64.4908747441819 -2.7596527488197 0.00611959410609001 TMEM51 other 0.00481393203785913 1 1 3.62402423062536 -2.7596527488197 1.94969317500285e-07 99.807355516141 26.7545823750904 3.73047704938448 0.000226161886214878 -182.080226004087 60.8794921627287 -2.99083023750253 0.00299885830438251 CAMTA1 other 0.00211639194146559 1 1 3.73047704938448 -2.99083023750253 0.0921332956963448 27.8727461944319 13.6953487375389 2.03519798791489 0.0426547048780518 -8.97280897625422 39.839704023097 -0.225222782053106 0.82194972783197 LGALS4 other 1 1 1 2.03519798791489 -0.225222782053106 0.435124126254423 2.90760078560743 2.27290745651372 1.27924292618021 0.201750056781576 2.43705317858902 16.2559456270322 0.149917650717065 0.880925226579633 LRRC34 other 1 1 1 1.27924292618021 0.149917650717065 4.9747278065549e-09 47.1505585076833 11.300404354166 4.17246649145796 3.88944588497678e-05 -66.7079376284065 22.7514895093689 -2.93202507031184 0.00361107615182792 SPATA5L1 essential 5.85923441056036e-05 1 0.418893321811999 4.17246649145796 -2.93202507031184 0.659275306432078 -31.3036268685006 49.4906110844541 -0.632516474995267 0.527502549341639 -84.3219409530904 99.6411352736337 -0.846256324975886 0.398044127490649 GATM other 1 1 1 -0.632516474995267 -0.846256324975886 0.216124447114439 -2.15701747605562 1.88982236098875 -1.1413863655032 0.254562586326788 -8.84743059117834 5.57488583045741 -1.5870155659228 0.113496710296294 RASGRP4 other 1 1 1 -1.1413863655032 -1.5870155659228 0.0392928433041164 2.19840469885131 1.28149598275568 1.71549870497756 0.087224833566872 -6.26415204001609 3.98732504266241 -1.57101615067564 0.117170207253117 SLFNL1 other 1 1 1 1.71549870497756 -1.57101615067564 1.33423570603348e-06 24.5185976490042 68.3402090812287 0.358772646127869 0.720002508196864 -441.823981066469 110.903136750708 -3.98387272002609 8.40523331204126e-05 BCL2 ts 0.0136919268153155 1 1 0.358772646127869 -3.98387272002609 7.2225669004019e-15 199.209440225174 23.9168140267413 8.32926325397853 2.55301285912847e-15 -51.8520671260677 117.078422070811 -0.44288320775887 0.658155162790497 RHNO1 other 9.91225081411157e-11 1 3.68731647243924e-11 8.32926325397853 -0.44288320775887 2.16690263627068e-12 291.816915182818 43.7450651173886 6.67085337282583 1.12374805266494e-10 -344.527443374792 136.111073294497 -2.53122273622334 0.0118466536206526 CTPS1 essential 2.83280847019326e-08 1 1.52571273110319e-06 6.67085337282583 -2.53122273622334 0.317555915407684 14.3581704114386 11.442335061066 1.25482869840913 0.210489195912656 -5.4132545776189 23.100550217754 -0.234334443404665 0.814880539207119 KNDC1 other 1 1 1 1.25482869840913 -0.234334443404665 0.00844103349934744 15.0558288963976 4.86342342111156 3.09572652692382 0.00213684123231278 3.58007732450418 15.4073987887705 0.232360917867166 0.816406236341162 METTL18 other 1 1 1 3.09572652692382 0.232360917867166 0.606372583489525 3.54757576128744 7.48850970889419 0.473735883265792 0.636015391162744 -8.7605437629812 15.114286466767 -0.579620068882757 0.5625838532888 CFAP46 other 1 1 1 0.473735883265792 -0.579620068882757 0.162321795285341 146.500209167113 76.8517063357846 1.90627139138611 0.057516292409036 92.546042491125 182.539185474187 0.506992743781099 0.612511288497354 COL8A2 other 1 1 1 1.90627139138611 0.506992743781099 1.66374978044366e-06 114.426380431846 32.2765225836392 3.54518923577745 0.000451250868137826 -125.423806950824 65.1306576270434 -1.92572609459951 0.0550299757749669 PWWP2B other 0.0169253265164533 1 1 3.54518923577745 -1.92572609459951 0.382668651977008 1.84865515381105 1.96939867164338 0.938690159808236 0.348600029608404 -2.79729785808716 4.12342356039948 -0.678392073264517 0.498014946585465 ANGPTL7 other 1 1 1 0.938690159808236 -0.678392073264517 4.51306174521627e-10 64.6830185901723 9.79548389345987 6.60335102315457 1.73028534926359e-10 -26.9096516182774 47.8925091403431 -0.561876003185006 0.574603909101121 FBXL14 other 5.53165978111158e-06 1 2.33986487780916e-06 6.60335102315457 -0.561876003185006 2.59751176927632e-12 176.075050934408 50.7832012739976 3.46719085282564 0.000598058428124166 -570.355128911969 106.327201099905 -5.36415068780062 1.56554296784024e-07 EXOSC10 essential 3.38871385419789e-08 0.00236318710995484 1 3.46719085282564 -5.36415068780062 0.559108560642898 2.4030268651597 5.61942774207485 0.427628394821647 0.669209313745341 -13.19659288037 15.8529378138965 -0.832438317445614 0.405782391681884 ZNF570 other 1 1 1 0.427628394821647 -0.832438317445614 2.5466908428612e-06 32.6399684504951 6.31106438467272 5.17186427851469 4.1894563681919e-07 14.4718821665761 30.85274556709 0.469063025042833 0.639357514669142 NINJ2 other 0.0255433091538979 1 0.00508306741152723 5.17186427851469 0.469063025042833 2.47272625251597e-09 63.2321921700809 12.2478022825159 5.16273782932852 4.35055059814794e-07 -115.460521404918 37.3784933179669 -3.08895600533526 0.00218989548466927 MLLT3 other 2.94773696562428e-05 1 0.00527373743507493 5.16273782932852 -3.08895600533526 6.48986764877351e-06 10.3878993100454 2.11189115115339 4.91876643565276 1.39534328997874e-06 -0.366607038394896 11.17899066857 -0.0327942878980675 0.97385907854979 FAM90A1 other 0.062984165531347 1 0.0165124924936084 4.91876643565276 -0.0327942878980675 0.00877637315373891 108.105408598508 133.724071213896 0.808421457836036 0.419450477686653 -1086.56080375066 402.543985855981 -2.69923497040992 0.00732027884215156 RRM2 essential 1 1 1 0.808421457836036 -2.69923497040992 0.000397057233828323 82.8556405217085 24.2527354779658 3.41634206982486 0.000717656847547333 -91.8631302483473 74.7016976771562 -1.22973283211526 0.219711947723051 TRAPPC12 other 1 1 1 3.41634206982486 -1.22973283211526 0.00444907723889722 1125.19351025826 415.134550788846 2.71043089070795 0.00708428852293449 -2505.90022240063 1920.10635801379 -1.30508407096407 0.192807769570631 RPS21 essential 1 1 1 2.71043089070795 -1.30508407096407 0.318649301895002 -2.90962755725075 10.1726119405178 -0.286025612130314 0.775043576747482 76.889139126334 53.8472515005928 1.42791204720054 0.154292366378469 C3AR1 other 1 1 1 -0.286025612130314 1.42791204720054 3.03261596504268e-14 99.9135552590509 12.8616219998708 7.76834797819857 1.13013089994669e-13 -62.1603833967537 24.4773803118708 -2.53950310877867 0.0115814809640233 MRM3 other 4.11253051019438e-10 1 1.60715915281418e-09 7.76834797819857 -2.53950310877867 5.88001184006709e-11 303.685182423573 72.0568491369704 4.2145220900002 3.26785339457088e-05 -517.924886226314 147.667255875615 -3.50737801115895 0.000517910779481505 PTEN ts 7.41469493032461e-07 1 0.354006558233863 4.2145220900002 -3.50737801115895 0.0038125198017995 283.381388243704 134.149954946655 2.11242253757291 0.0354344211792436 -847.084462211897 413.199961997428 -2.05005939041487 0.041183522169803 RPS7 essential 1 1 1 2.11242253757291 -2.05005939041487 0.555047635073815 -4.78970682600686 4.94496618289873 -0.968602544254235 0.333475033703551 -13.841665048491 18.5294893246811 -0.747007367874626 0.455607623566621 PRND other 1 1 1 -0.968602544254235 -0.747007367874626 1.63024437168963e-11 72.52380739682 11.7383598621048 6.17835951945472 1.99305819047451e-09 -86.219380918349 36.1557322241558 -2.38466698402931 0.0176840850287753 RNASEH1 other 2.08557162470255e-07 1 2.63203264634063e-05 6.17835951945472 -2.38466698402931 1.42132164855084e-09 2281.13126246282 390.277551261048 5.84489488337756 1.24895675011254e-08 -1835.66774090527 1462.42531339519 -1.2552215310357 0.210314212516989 PRNP other 1.70743369640412e-05 1 0.000160878118981996 5.84489488337756 -1.2552215310357 0.0981450677732761 15.0020116165921 7.57844550507783 1.9795631711728 0.0486092611048628 24.1506124743784 15.3440400787887 1.57394091454204 0.116489240536632 FRMD5 other 1 1 1 1.9795631711728 1.57394091454204 1.2458483024027e-06 1020.31816404404 191.515417774201 5.32760325984305 1.88402699361914e-07 681.488185738332 494.354644732805 1.37854107976809 0.16900226742296 CYP4F11 other 0.0128135497902118 1 0.00231961403454388 5.32760325984305 1.37854107976809 0.00354226824638191 87.6351880142587 37.0531385995094 2.36512185813644 0.0186203172836435 -101.649544816989 72.3791230422946 -1.40440420585906 0.16116837316614 TLN2 other 1 1 1 2.36512185813644 -1.40440420585906 0.347614980388449 38.4725543582015 27.7597982835014 1.38590900284268 0.16673972217162 -19.1936364998105 51.906149405308 -0.369775772614867 0.711794162506787 LGALS9C other 1 1 1 1.38590900284268 -0.369775772614867 8.95236193153417e-08 100.41365858238 20.8576995456942 4.81422499937725 2.2826133122269e-06 -118.922908972809 38.8405804520273 -3.06182110536923 0.00238646702169789 TVP23B other 0.000991205513059463 1 0.0266746191666836 4.81422499937725 -3.06182110536923 0.0324721989247319 1.72470674006252 1.5590137582418 1.10628064117123 0.26943603977915 -6.75946771790152 2.90314850734863 -2.32832309500928 0.020517710067237 FBXW10 other 1 1 1 1.10628064117123 -2.32832309500928 0.00526943104753002 155.237581240891 47.6936438211634 3.25489035442511 0.00125573492164414 227.43867093046 219.855392986321 1.03449211702808 0.301687305474687 ZNF217 other 1 1 1 3.25489035442511 1.03449211702808 0.00426309635580292 105.929462253967 33.1071180404983 3.19959780625994 0.00151409148055753 37.91770769688 57.7506969066676 0.656575759737753 0.51192561334843 SCG2 other 1 1 1 3.19959780625994 0.656575759737753 4.36215312424304e-11 69.2914473224168 10.5987693297643 6.53768802457351 2.47749392254732e-10 -51.4337468777505 19.8369708877358 -2.592822622407 0.00995758467061622 ATPAF2 other 5.52335828591653e-07 1 3.33990955698605e-06 6.53768802457351 -2.592822622407 1.01229844447377e-05 263.563797202687 56.2581840107098 4.68489699476457 4.14771372062484e-06 390.142038513299 153.445616892771 2.54254273542354 0.0114757449863154 CYP4F22 other 0.0965935175716871 1 0.0477318894969507 4.68489699476457 2.54254273542354 1.7734172110982e-05 88.0769937199406 25.8264830474205 3.4103363418945 0.000732247433880655 -215.664314269397 80.3620626638156 -2.6836582725807 0.00766212449822012 PPIH essential 0.165548496656017 1 1 3.4103363418945 -2.6836582725807 0.729802960888645 -5.65100935147602 9.56739870819418 -0.590652644865328 0.55517140360777 -10.0554025783611 17.9115037588556 -0.56139354426842 0.574923446853395 DRC3 other 1 1 1 -0.590652644865328 -0.56139354426842 1.31920064773611e-09 26.0168373944862 9.26818283289521 2.80711309472074 0.00530730366963607 -62.3890515498444 16.0937244306671 -3.87660742040295 0.000128694413903431 ZNF57 other 1.58673453909699e-05 1 1 2.80711309472074 -3.87660742040295 3.20757044294182e-09 19.2562357259661 3.29518411782095 5.84375107352118 1.25673301395073e-08 -11.7530125172865 12.3475220407332 -0.951851916401898 0.341890476349206 C20orf196 other 3.804178545329e-05 1 0.000161867212196854 5.84375107352118 -0.951851916401898 0.000108224934692048 98.6012260727761 45.871814172415 2.14949480092876 0.0323541471539686 -295.356438493311 105.439692823039 -2.80118834364408 0.00540530111817122 JMJD1C other 0.92889461446185 1 1 2.14949480092876 -2.80118834364408 0.00725631817036316 920.615740286812 321.045000877028 2.86755980554714 0.00441098340421224 -139.792540598182 464.804236915772 -0.30075573649195 0.763796074768978 SYNPO other 1 1 1 2.86755980554714 -0.30075573649195 0.00500629992240518 24.4146122064206 8.46900495294825 2.88281945069843 0.00420976292399082 0.304792752599817 14.7059930055488 0.0207257512284152 0.983477425173638 ZNF556 other 1 1 1 2.88281945069843 0.0207257512284152 0.576766123381525 200.640936614257 451.198315664487 0.44468458690669 0.656866229582729 -1367.67998454468 1544.33411097816 -0.885611458571233 0.376531541867803 MAL other 1 1 1 0.44468458690669 -0.885611458571233 2.02367116100253e-06 13.2592081659293 6.50092171393347 2.03958896128694 0.042217505479299 -36.4298922455095 11.2885173389164 -3.22716359923723 0.00138053186706404 ZNF554 other 0.0204249130279985 1 1 2.03958896128694 -3.22716359923723 0.000661229442748285 27.5655814809809 11.2173392174249 2.45740820944069 0.0145329165697116 -37.161066218669 19.8236839435481 -1.87457923181647 0.0617758922108615 RAB33B other 1 1 1 2.45740820944069 -1.87457923181647 6.93976726396765e-11 183.697579538215 70.8486459578582 2.59281708287666 0.00995913308338505 -557.397221968033 123.025042221301 -4.53076228956193 8.32667111522401e-06 THOP1 other 8.7302272180713e-07 0.122776765593978 1 2.59281708287666 -4.53076228956193 0.288967798727145 -0.569879431849439 4.65348813380743 -0.122462852695225 0.902609336194773 28.0231897107734 18.4338274731357 1.52020462118422 0.129446986798856 GAP43 other 1 1 1 -0.122462852695225 1.52020462118422 0.0125242330836144 701.664614365656 242.803610442222 2.88984423702638 0.00411921499255093 318.24483207627 344.185867225421 0.924630736996063 0.355859119572704 LAMB2 other 1 1 1 2.88984423702638 0.924630736996063 5.02207445882512e-17 217.139520423887 59.9388253979069 3.62268561291276 0.000339263730730012 -443.809850143729 84.966185480017 -5.22337030474444 3.18321458976498e-07 USP19 other 7.07961836460577e-13 0.00479646774385787 1 3.62268561291276 -5.22337030474444 0.000157256201029392 164.946315249385 40.8046594149793 4.04234020364924 6.65802084567781e-05 -124.735121924874 118.562588787873 -1.05206138968545 0.293577763773348 ORMDL3 other 1 1 0.702687520052836 4.04234020364924 -1.05206138968545 0.000677921379681696 14.1405339691519 12.3461066693947 1.14534357654672 0.252944640049963 -48.951804635733 16.8548415785952 -2.90431710125946 0.00394327856164262 SERF1A other 1 1 1 1.14534357654672 -2.90431710125946 0.356393507236908 -15.2704782156567 33.1580118697724 -0.460536605018155 0.645444886943632 -143.206571812277 99.8141781053634 -1.43473176386935 0.15234317981639 KLF11 other 1 1 1 -0.460536605018155 -1.43473176386935 0.162798132156092 165.012422520561 87.7510782822061 1.88046034021238 0.0609534348786282 -180.090764098814 535.234750439691 -0.336470612102206 0.736736548164929 LRRC15 other 1 1 1 1.88046034021238 -0.336470612102206 1.98218205955918e-08 163.327487168559 31.7494900975516 5.14425544053554 4.74769957685986e-07 -41.0996386162384 43.2484156512145 -0.950315473928449 0.342685182059312 SMN1 other 0.0002270787767431 1 0.00574424171804275 5.14425544053554 -0.950315473928449 0.4242169352139 43.5725569475447 35.9127121143723 1.21329062558065 0.22592773407754 -57.8306425081218 146.251619746595 -0.395418817298043 0.692801475535089 EIF2AK3 other 1 1 1 1.21329062558065 -0.395418817298043 2.36238406985876e-05 39.7076627864719 98.2581286008413 0.404115805500207 0.686399204255923 -654.860593182769 169.184728327776 -3.87068383568316 0.000131717110832812 MOB3A other 0.21792993044447 1 1 0.404115805500207 -3.87068383568316 0.419225280898008 -35.5293923142428 32.4954420827757 -1.09336540871605 0.275063552448923 -111.133133730727 133.968357837247 -0.829547629939143 0.407418828699406 KRCC1 other 1 1 1 -1.09336540871605 -0.829547629939143 3.10732009442968e-23 53.5155470796304 10.9898801688936 4.86952962700213 1.76119047799467e-06 -90.3457802818686 15.7196666377386 -5.7473089197053 2.11392652524051e-08 NME6 other 4.59945520377482e-19 0.000320682653878986 0.0207063164497834 4.86952962700213 -5.7473089197053 0.000162938999190704 414.799775303844 103.809757499776 3.99576865695635 8.01857484558085e-05 -283.068522828586 434.86185223318 -0.650938962281752 0.515555958540873 CYCS essential 1 1 0.839384414835403 3.99576865695635 -0.650938962281752 0.00476861093654733 -41.4625769755938 13.6483023760931 -3.03792924812549 0.00258008077896616 -86.0643294419778 56.3110038637496 -1.52837498067375 0.1274166473426 CD8B other 1 1 1 -3.03792924812549 -1.52837498067375 0.430105846764421 1.9475598972296 5.16439820711082 0.377112650714661 0.706341424939265 -14.9540770500136 12.5685748310135 -1.18979894308412 0.235012968242918 SLFN12 other 1 1 1 0.377112650714661 -1.18979894308412 6.42086972392172e-06 262.159222565103 52.7306940155402 4.97166266174768 1.08428892102776e-06 335.169430936252 144.961712512093 2.31212383689446 0.0214053141601237 CALB2 other 0.0623273824101081 1 0.0129052067380724 4.97166266174768 2.31212383689446 0.973223986047881 -2.01053762852181 9.11372838068534 -0.220605392715316 0.825542616144478 -2.31443883617164 22.4277273611514 -0.103195424079421 0.917873538048127 CCL11 other 1 1 1 -0.220605392715316 -0.103195424079421 0.70052108418578 -3.96110486606667 4.70044956985861 -0.842707661723902 0.400023346461107 -1.84321850482838 8.99804166356209 -0.204846629271852 0.837822596310087 FRMD3 other 1 1 1 -0.842707661723902 -0.204846629271852 0.141359969359134 24.3173821689451 12.3724560760708 1.96544501911601 0.0502300140581112 27.0473573284654 69.2760657432078 0.39042859952129 0.696480230497314 SNTB1 other 1 1 1 1.96544501911601 0.39042859952129 0.0117943453490635 20.6549581624479 7.0231398905109 2.94098629451411 0.00351094440679592 -16.4606105019637 38.8165070468301 -0.424062125994615 0.671806324350104 MTBP essential 1 1 1 2.94098629451411 -0.424062125994615 0.142838402334213 11.6559062107954 7.11478639441863 1.63826509534273 0.102368017796866 -15.2068542739639 17.2980069103393 -0.879110197653721 0.380013775694384 TEFM other 1 1 1 1.63826509534273 -0.879110197653721 1.93894269038045e-07 133.467880017022 23.4265398343783 5.69729379415901 2.767804553247e-08 43.8032801732643 129.477194351861 0.338308845758787 0.735353006737163 MRPL13 essential 0.00210530397321509 1 0.00035231384158281 5.69729379415901 0.338308845758787 3.26486592811403e-16 143.9685027714 55.4568753741346 2.59604425601208 0.0098652774244382 -433.655674934603 84.0042138078761 -5.16230859473795 4.29269863402511e-07 MALT1 other 4.56232364794654e-12 0.00645836509489077 1 2.59604425601208 -5.16230859473795 0.00925845347057866 -175.586370565799 82.2140508276575 -2.1357221642548 0.0334608461371946 -457.677377141862 166.965831429559 -2.74114394078857 0.00646665710472878 ISG20 other 1 1 1 -2.1357221642548 -2.74114394078857 0.0630062562947363 16.0471658090211 14.8668935963778 1.07938929575247 0.281229659521579 -53.203533889905 35.1258355133913 -1.51465532740486 0.130849894606439 MBOAT1 other 1 1 1 1.07938929575247 -1.51465532740486 0.0593828280969558 54.8112964094359 24.0077872083449 2.28306323834726 0.023082041001262 14.691709924268 56.6541475187193 0.259322760428328 0.795552965218673 ID4 other 1 1 1 2.28306323834726 0.259322760428328 1.9995595091737e-06 -55.5009057747761 22.6220573994355 -2.45339779644274 0.0146843037171671 -169.217316113343 32.4180863354568 -5.21984284828879 3.22819878220632e-07 CXCR6 other 0.0201975506021636 0.00486392710515026 1 -2.45339779644274 -5.21984284828879 1.52909477966219e-05 276.756369906299 75.2172193043434 3.67942836049933 0.000274182282744883 -730.444176230567 347.238668976316 -2.10357958802217 0.0361953498832791 CEBPB other 0.14358199981028 1 1 3.67942836049933 -2.10357958802217 0.883335923978056 -24.2603828529417 52.6605723249805 -0.460693490059799 0.645331450906729 5.88382773534386 143.852308764315 0.0409018651552116 0.967399637864827 TPSAB1 other 1 1 1 -0.460693490059799 0.0409018651552116 1.23819051644255e-35 207.421722387628 14.3574257588205 14.446999474136 1.57959927379732e-36 -9.58318540345991 101.123179210258 -0.0947674457854448 0.924560770610693 PAIP1 other 1.88440214697391e-31 1 2.41110033152423e-32 14.446999474136 -0.0947674457854448 2.95948126254318e-12 218.104164364386 28.8018898990079 7.57256433967199 3.98000124045869e-13 109.184121403839 149.283435516822 0.731388054045256 0.465079067899246 CLEC7A other 3.85502029258874e-08 1 5.6121997491708e-09 7.57256433967199 0.731388054045256 0.00015935208199497 13.4503178476013 3.44976640060288 3.89890684924369 0.000118482330167716 -31.8930199597087 24.2976249239786 -1.31259825021969 0.19028929910781 C5orf34 other 1 1 1 3.89890684924369 -1.31259825021969 0.00295100804052825 12.5387488299401 7.81175816309657 1.60511226386581 0.109458582032967 -52.9134169647535 20.3351345008213 -2.60206869851863 0.00969860480413217 SERHL other 1 1 1 1.60511226386581 -2.60206869851863 0.841983355360433 2.95404115475119 11.4517202100709 0.257956106206065 0.796607118347723 14.1719642201104 24.4844755522199 0.578814285398307 0.563122942566639 NEGR1 other 1 1 1 0.257956106206065 0.578814285398307 3.24291457188836e-23 181.757620192492 16.450249013103 11.0489281984558 3.7644897853524e-24 6.62888045313691 115.863491613975 0.0572128490242854 0.954412501938787 ZNF131 essential 4.79983785785196e-19 1 5.66103973921294e-20 11.0489281984558 0.0572128490242854 0.608426864345649 -1.61687115000327 5.70868505099713 -0.283230049575227 0.777187727867995 19.4066713447339 22.9922097785137 0.844054204953778 0.399283747615586 MACROD2 other 1 1 1 -0.283230049575227 0.844054204953778 3.48393851463776e-27 209.826568241836 29.7872411216046 7.04417597404313 1.15362174470412e-11 -182.255658373765 56.1933121381015 -3.24336920959297 0.00130633478108577 DPAGT1 essential 5.2311336797286e-23 1 1.59453597553003e-07 7.04417597404313 -3.24336920959297 7.25518810159039e-09 1031.09741835994 727.690793534201 1.41694443233529 0.157478100140137 -5399.73749191264 1185.03787738331 -4.55659485233996 7.42130257092053e-06 BSG other 8.47623625908806e-05 0.109575532459642 1 1.41694443233529 -4.55659485233996 3.603789205885e-17 48.9354525568099 11.8548848370693 4.12787245336983 4.67892730910136e-05 -84.9240340270985 22.3641135911547 -3.79733512267113 0.000175072106390106 HINFP essential 5.08782960086844e-13 1 0.500738800620028 4.12787245336983 -3.79733512267113 8.20078930466438e-09 544.046446999521 102.771093257653 5.29376918892517 2.23026970121346e-07 -773.938089823531 309.304258132921 -2.50219022038467 0.0128414025022396 CERS6 other 9.56048017137773e-05 1 0.00273810211217976 5.29376918892517 -2.50219022038467 0.000129194123536971 60.5389257036963 22.0411087631913 2.74663703873176 0.00636844025985116 -210.256539157061 86.0017925658731 -2.4447925198305 0.015042955277565 SPTLC3 other 1 1 1 2.74663703873176 -2.4447925198305 1.69490393726528e-06 148.348159758344 28.3120178718255 5.23975932870445 2.94426699094348e-07 16.7189632389454 69.6630267476687 0.239997657573856 0.810487681129811 COPRS other 0.0172303934262388 1 0.00359612770273836 5.23975932870445 0.239997657573856 5.75562147539835e-11 70.1085919121767 10.5412001609746 6.65091174074574 1.26057918733457e-10 -42.9239968634479 47.9226980402802 -0.895692409208038 0.37109032885217 TP53RK essential 7.25841424262486e-07 1 1.70984960970061e-06 6.65091174074574 -0.895692409208038 0.0811007602933278 7.06136770762157 3.34856372471667 2.1087750713835 0.0357432288956414 -6.76657925354118 17.3335510840364 -0.390374668222079 0.696520064010399 CLEC12A other 1 1 1 2.1087750713835 -0.390374668222079 0.00162940080194036 315.84845770587 113.393461757534 2.78542036560485 0.00566650227871668 -187.505275336357 249.323100002815 -0.752057371877055 0.452572835536578 BPGM other 1 1 1 2.78542036560485 -0.752057371877055 8.04146701938199e-07 123.211814931588 23.4739587092218 5.24887244021535 2.79820883797363e-07 -15.7426097413273 101.038214649673 -0.155808471041489 0.87628254226132 POP7 essential 0.00837840448749409 1 0.00342192958795795 5.24887244021535 -0.155808471041489 6.6583065748434e-08 3.99881142460714 7.35384441949335 0.543771556277043 0.5869785049272 -83.426586340055 15.557446604639 -5.36248578961397 1.57883899758132e-07 ALG14 other 0.000740736606451328 0.00238309958294924 1 0.543771556277043 -5.36248578961397 4.57658754156175e-14 161.36486884646 39.4945201797023 4.08575336811893 5.56702654210675e-05 -210.190467976911 55.381870090494 -3.79529379620911 0.000176552540496986 SUCLG2 other 6.18434274491239e-10 1 0.590995537710053 4.08575336811893 -3.79529379620911 1.51042490743666e-05 -20.2580051523263 44.9656193787725 -0.450522097375795 0.652640068248653 -408.645704914134 88.49993385573 -4.6174690433136 5.64015902691091e-06 STARD5 other 0.141904420053674 0.0835533158246582 1 -0.450522097375795 -4.6174690433136 2.1190880777351e-07 39.7239486758799 7.34075048183475 5.41142881428539 1.23026495571474e-07 -8.5389056788676 19.1851572250549 -0.445078743879993 0.656564705676122 CSDC2 other 0.00229687956745708 1 0.00152614367756413 5.41142881428539 -0.445078743879993 0.320786885998331 23.1782525656784 20.5526113412281 1.12775219561435 0.260272092042863 -46.5767783292284 68.6787726965838 -0.678183032405081 0.498147285055034 RCAN2 other 1 1 1 1.12775219561435 -0.678183032405081 3.29426020470264e-05 -92.2607913533665 41.2975546227104 -2.23404974450062 0.0261724311032296 -371.771345943636 81.2805628612923 -4.57392681418896 6.86025928764987e-06 IL16 other 0.299580023015658 0.101435793827191 1 -2.23404974450062 -4.57392681418896 0.000374997362468489 4.0917262857905 6.7817744473973 0.603341546895712 0.546710239292716 -34.5239788200745 12.7937450406038 -2.6985045200217 0.00733599683452974 ABCG4 other 1 1 1 0.603341546895712 -2.6985045200217 4.26643681618131e-25 1431.26462158126 132.930638054049 10.7670033224343 2.88508044045502e-23 -1057.65033953058 572.169121859561 -1.84849251580232 0.0654564130610625 GNB2 other 6.36339051133443e-21 1 4.3293517089468e-19 10.7670033224343 -1.84849251580232 0.996913931265479 -0.930192396413784 12.3161055331093 -0.0755265042113479 0.939843301507293 -1.21804095645404 18.9404398113655 -0.0643090112259765 0.948764584516247 CFAP53 other 1 1 1 -0.0755265042113479 -0.0643090112259765 4.56711143803223e-11 37.592732336868 13.7281564213403 2.73836713270767 0.00652133065790664 -88.0088114287772 25.8980204214193 -3.39828334354035 0.000764090732331191 C2CD2L other 5.77739596911077e-07 1 1 2.73836713270767 -3.39828334354035 2.80488709689956e-07 451.049709203626 164.197118452278 2.74700136917884 0.00635494560009492 -1443.34359739449 366.087846278403 -3.94261544617587 9.90422936486475e-05 GNG12 other 0.00301833900497361 1 1 2.74700136917884 -3.94261544617587 0.70044117387735 -25.2086864451178 113.741538196616 -0.221631312929332 0.824742270029094 -274.990605953349 325.731721541948 -0.844224212034367 0.399174808936075 PRSS27 other 1 1 1 -0.221631312929332 -0.844224212034367 0.775408692647435 -3.73295623387728 24.4982362056009 -0.152376530397884 0.878986599481148 -31.4499246687565 44.5632887637958 -0.705736168518763 0.480868891987955 MYOZ2 other 1 1 1 -0.152376530397884 -0.705736168518763 0.478854987570295 -216.510242274068 296.851355941861 -0.729355746370489 0.466320937315654 -630.38971980015 539.984698642798 -1.16742144987548 0.243914814106831 SYNPO2 other 1 1 1 -0.729355746370489 -1.16742144987548 0.000418291923858014 6.45770876828898 1.62551541619415 3.97271456422636 8.79507405309863e-05 2.19719586443137 4.24728571866155 0.517317649429004 0.605294077835833 DNAJB7 other 1 1 0.917414174478719 3.97271456422636 0.517317649429004 2.54554362087903e-20 69.9690991606304 9.01016133604454 7.76557672510522 1.1510639378779e-13 -146.925031578559 33.0111563730524 -4.45076900421751 1.18884823235234e-05 CLP1 essential 3.7014749791202e-16 0.174618028367911 1.63669781326858e-09 7.76557672510522 -4.45076900421751 0.00165669500212949 64.1463392390122 22.5355895569736 2.84644602160685 0.00470828374046184 -80.4556601891773 62.6622736919728 -1.28395692414021 0.200091727204331 RSPH9 other 1 1 1 2.84644602160685 -1.28395692414021 0.00386496332168732 42.4823973136436 85.4173172390094 0.497351107326071 0.619284103109128 -424.811395846351 154.745791217755 -2.74522100086436 0.00638979910207879 COPS9 other 1 1 1 0.497351107326071 -2.74522100086436 3.93479243883249e-07 175.373847209825 34.5280149576814 5.07917548763718 6.47216989481076e-07 -62.6646696889452 96.008312445025 -0.652700459919316 0.514420965498627 GTPBP2 other 0.00419212786433214 1 0.00778148986453098 5.07917548763718 -0.652700459919316 0.0286185240708522 14.240987705772 8.93976105040784 1.59299422271721 0.112151833082427 -35.985362288641 21.2240187102098 -1.69550181706777 0.0909559959126757 FGGY other 1 1 1 1.59299422271721 -1.69550181706777 0.00807936752949104 33.6235085290044 10.7465866801812 3.1287616737892 0.00192342497353344 26.0680384341818 17.4247305890321 1.49603681394019 0.135668010621176 IL17D other 1 1 1 3.1287616737892 1.49603681394019 1.02105064726883e-21 401.143349322088 57.6843957499322 6.95410507654592 2.05472735906387e-11 -300.482944504668 103.108285744834 -2.91424634144617 0.00382075352518829 ZNF24 other 1.49869814006119e-17 1 2.82607200965645e-07 6.95410507654592 -2.91424634144617 0.000919883660429419 3.44021111499756 19.0177405738308 0.18089483877656 0.856566451420626 -162.575072120536 45.3843689352698 -3.58218205815336 0.000394583897826184 MANEA other 1 1 1 0.18089483877656 -3.58218205815336 0.0184585515856078 -27.7476287843384 100.616800954977 -0.275775303140025 0.782899213003004 -482.09078581411 182.090505910088 -2.64753389203144 0.00851085498105583 C2orf54 other 1 1 1 -0.275775303140025 -2.64753389203144 1.29001075111502e-07 299.554804290768 78.9750281084523 3.79303194269719 0.000177904164509791 -356.575088440032 146.663355700531 -2.43124866969577 0.0155955656763307 AFF1 other 0.00141398078429717 1 1 3.79303194269719 -2.43124866969577 7.40325185288711e-14 312.761442311419 38.3378534012543 8.15803219439475 8.06523819597128e-15 197.220433049057 206.959906344437 0.952940289414462 0.341346372146811 FIBP other 9.97514154658009e-10 1 1.15978125258067e-10 8.15803219439475 0.952940289414462 0.513146713999516 8.78644251557597 7.63355260130028 1.15102927489873 0.250612972964209 4.84216630812849 40.694487982698 0.118988259790545 0.905362225644615 CARNS1 other 1 1 1 1.15102927489873 0.118988259790545 0.838183057504822 5.18960698210534 9.12942352824631 0.568448485936573 0.570129162891029 2.4341023460965 23.228306293499 0.104790349986806 0.916607818019975 BANP essential 1 1 1 0.568448485936573 0.104790349986806 1.26989370683741e-20 1287.23076045078 131.561227961735 9.78427140270514 7.30971945972638e-20 -932.856313890079 710.093149951604 -1.3137097773069 0.189921577005563 PPP1CA essential 1.85137803519826e-16 1 1.08446997904501e-15 9.78427140270514 -1.3137097773069 0.00772120591874284 -32.0861092833252 11.2227236395027 -2.85903050934854 0.00453093244758403 52.5616215203523 60.5128421071681 0.868602757531465 0.385721571370113 CTSW other 1 1 1 -2.85903050934854 0.868602757531465 1.35047124094602e-09 874.372049261957 166.690356088333 5.24548672029118 2.84085552104653e-07 -484.295353983826 239.012691195199 -2.02623279777352 0.0435701498264529 NIPAL4 other 1.6236715729894e-05 1 0.00347322996003148 5.24548672029118 -2.02623279777352 0.444479553765931 237.781942282362 186.493861986694 1.27501216259508 0.203232776640455 137.105077236259 530.029235930906 0.258674555933612 0.796053178462103 MUCL1 other 1 1 1 1.27501216259508 0.258674555933612 0.0269461463503562 26.0332210779986 9.63583154052472 2.70170985955001 0.00727685034084095 24.0135601416528 38.8153133363359 0.618662019640922 0.536591890926382 PDE3A other 1 1 1 2.70170985955001 0.618662019640922 0.248939387052477 -31.9292530405534 28.5030293968646 -1.12020559625377 0.263468825900723 -90.030950105874 57.3211329210565 -1.57064149848304 0.117257264501949 RASGRP1 other 1 1 1 -1.12020559625377 -1.57064149848304 0.000866968495142183 29.3697815153255 8.17945003531972 3.59067924964438 0.00038243155461892 -78.5500255313186 53.5125547256109 -1.46788031208917 0.14313452059856 KLHL6 other 1 1 1 3.59067924964438 -1.46788031208917 1.65120379481365e-11 191.460691430263 31.3089401022135 6.1152083336327 2.80812312517749e-09 -105.592781191368 73.5390997404386 -1.43587263869242 0.152015380700355 CHCHD1 essential 2.11221989432563e-07 1 3.6926819096084e-05 6.1152083336327 -1.43587263869242 0.00265310616790286 187.125925180664 62.5828033138696 2.99005342157936 0.00300559264916984 -183.447009881666 171.535128607883 -1.06944280958924 0.28567620785009 MRPL52 other 1 1 1 2.99005342157936 -1.06944280958924 0.16009306431459 1.36425926957529 19.1119605044077 0.0713824868600299 0.943138360803766 -82.5444007654449 44.7558950452477 -1.84432465671826 0.0660687628510648 SMPDL3A other 1 1 1 0.0713824868600299 -1.84432465671826 0.0183981520624554 -20.5399512103583 8.57209895044245 -2.39614023696007 0.0171462116890278 -43.0743015464772 21.6418797052428 -1.99032164179539 0.0474113422554252 RND1 other 1 1 1 -2.39614023696007 -1.99032164179539 2.75054864821104e-05 238.539959965745 53.3550281826689 4.4708056220881 1.09675244697679e-05 -118.53063722556 287.9802857952 -0.41159288698621 0.680924114562167 RAD9A essential 0.252336466069512 1 0.122671761194354 4.4708056220881 -0.41159288698621 0.0729761545742498 107.580657911572 48.8149836495131 2.20384500554155 0.0282538041788564 -83.3316022676731 263.210027523932 -0.316597369224834 0.751757514999189 EFEMP2 other 1 1 1 2.20384500554155 -0.316597369224834 0.176115803562766 1.96422181780653 3.32816446509601 0.590181716801025 0.555486659022557 -11.2076142899908 7.84831438685095 -1.42802820294355 0.154262010807915 AGAP5 other 1 1 1 0.590181716801025 -1.42802820294355 5.59448780795836e-07 50.2222419958424 36.8500726186769 1.3628804077414 0.173884491616984 -340.388207068607 78.6682044805268 -4.3268841499092 2.02771495063057e-05 WASHC2C other 0.00589323345690334 0.29606665994157 1 1.3628804077414 -4.3268841499092 5.09420329786168e-11 225.090631976169 32.5869749163353 6.90738040441227 2.83522075227513e-11 -63.1630807583676 171.627240658322 -0.368024799070874 0.713107534948871 TMEM134 other 6.43499760585887e-07 1 3.89105696042238e-07 6.90738040441227 -0.368024799070874 6.37021341052073e-16 177.07738848685 20.105958043964 8.80720968877235 9.27187307210302e-17 67.632738591967 134.495115148017 0.502863903402992 0.615417026081712 ZMAT3 other 8.87179621683222e-12 1 1.3522099688355e-12 8.80720968877235 0.502863903402992 0.473822935779936 -8.48859444479366 8.22302973216361 -1.03229523925851 0.302720747447498 -17.7970728715153 17.616256459376 -1.01026417914364 0.31313923421566 ZFAND4 other 1 1 1 -1.03229523925851 -1.01026417914364 0.00864607718225938 -17.0289507740977 5.49084261544012 -3.10133652824299 0.00209904024397127 -7.29422901787849 12.8155572023809 -0.56916986929943 0.569642653143696 THEMIS other 1 1 1 -3.10133652824299 -0.56916986929943 0.316687375558294 21.8879872407372 50.16987846822 0.436277461875895 0.662930546963822 -169.994050488576 122.128006003354 -1.39193339882998 0.164912256743221 SLFN11 other 1 1 1 0.436277461875895 -1.39193339882998 0.592213301847183 -3.49262903894194 3.79144724340385 -0.921186242276803 0.357653713605494 2.57882735774937 12.3491605604617 0.208826125883082 0.834718096298683 FAM71D other 1 1 1 -0.921186242276803 0.208826125883082 0.024877468068254 -86.5587349824355 65.7706823863672 -1.31606867743822 0.189123317622777 -543.158312406085 208.704745559549 -2.60252018203921 0.00969877791995158 CCL19 other 1 1 1 -1.31606867743822 -2.60252018203921 1.00841415339786e-08 419.258222232743 67.1484782316212 6.24374867866042 1.41978743180189e-09 313.49794253989 357.710605515916 0.87640102838925 0.381497293916086 CORO1B other 0.000117036546643356 1 1.88107636839432e-05 6.24374867866042 0.87640102838925 7.00666170277403e-18 23.5142883096652 6.01376382794127 3.910078443788 0.000113163750165207 -65.5736770600803 13.3654431244763 -4.90621047498188 1.49577187551127e-06 FUT10 other 9.98028892943133e-14 0.0223587979951424 1 3.910078443788 -4.90621047498188 0.0258166601203764 17.3811251974037 34.8707005025211 0.498444968036905 0.618512867307776 -164.290916748766 72.553154955338 -2.26442140041876 0.0242169907743117 LRRC20 other 1 1 1 0.498444968036905 -2.26442140041876 7.79450370175277e-11 114.214223373728 16.1929893583089 7.05331306323143 1.10141669934614e-11 36.9341456318959 87.3124777690617 0.423011081297972 0.672573995492197 MUS81 other 9.78521994718042e-07 1 1.52314915352578e-07 7.05331306323143 0.423011081297972 0.0278193112433647 3.90989979640507 2.02123680064225 1.93440956307678 0.0539440905200496 -5.05251243339458 4.69854676371382 -1.07533513817812 0.283034813554953 TMEM217 other 1 1 1 1.93440956307678 -1.07533513817812 1.14144838696625e-15 2.78676270337435 3.03710287105261 0.917572707179493 0.359579683274352 -35.9921364462873 5.80767782860178 -6.19733695781684 1.89335910966807e-09 ZNF596 other 1.58455865078656e-11 2.8873726422438e-05 1 0.917572707179493 -6.19733695781684 0.333827731639332 -2.15463695150979 1.83306258429566 -1.17543010804385 0.2406964977513 4.94367153960954 7.40331313124628 0.667764749642209 0.504765073091217 COL6A5 other 1 1 1 -1.17543010804385 0.667764749642209 7.38371369500846e-30 7240.43111988449 563.612830314813 12.8464625545168 1.07564698007815e-30 1540.84393144584 3038.99617472233 0.507023978596033 0.612490505491552 CFL1 essential 1.11560530217883e-25 1 1.63530610381282e-26 12.8464625545168 0.507023978596033 4.29487052114421e-16 255.908738853794 30.598224254233 8.36351602392063 1.90119958247126e-15 -174.832076038916 123.132452713812 -1.41987000328228 0.156618995790792 TMCC1 other 5.99649822162154e-12 1 2.74913459625344e-11 8.36351602392063 -1.41987000328228 0.000135846181679928 30.3449370755948 11.3515827263988 2.67318996892175 0.0079010987324749 -39.3267264547388 21.0597034291919 -1.86739222548719 0.0627666561533347 NAA16 other 1 1 1 2.67318996892175 -1.86739222548719 4.33981943368235e-13 190.396326098804 35.2057409541973 5.40810450052761 1.24886650676315e-07 -253.184522168436 93.5337345301551 -2.7068792178592 0.00715644405071956 FAM192A other 5.76024233432658e-09 1 0.00154871935503699 5.40810450052761 -2.7068792178592 3.98659831245531e-08 128.6106496601 21.6771202847382 5.93301360931452 7.72115288501797e-09 22.3562601344927 86.9792551417454 0.257029795185759 0.797320957992727 RAB43 other 0.00044917003186434 1 0.000100143352918683 5.93301360931452 0.257029795185759 0.0586639376864395 10.8868144565085 4.94260417014469 2.20264744692063 0.0283322469619232 14.830450894136 11.7374715155347 1.26351325960686 0.207324518275539 FADS6 other 1 1 1 2.20264744692063 1.26351325960686 0.39191325323011 1.75154089190449 2.10101902720819 0.833662555751299 0.405093001405051 -5.29822248972887 5.85126833881587 -0.905482740311492 0.365890943958998 HOXC5 other 1 1 1 0.833662555751299 -0.905482740311492 0.0638654789028491 -9.07235943079077 4.22238040371786 -2.14863621070296 0.0324132705150698 6.45954776842418 10.0727946662725 0.64128655278293 0.521795555369973 RAB37 other 1 1 1 -2.14863621070296 0.64128655278293 4.50117813854853e-10 119.850300838355 32.6179302080927 3.67436867004577 0.000279446414679895 -179.82748666901 46.1992742444973 -3.8924309874939 0.000120793817299989 DCP2 other 5.51754416223279e-06 1 1 3.67436867004577 -3.8924309874939 1.245474018753e-26 697.744576045038 58.3795090246893 11.9518746851734 1.9751391242562e-27 116.084897613521 314.781876965258 0.368778846903987 0.71253874619173 SNX32 other 1.86696555411074e-22 1 2.98838549499963e-23 11.9518746851734 0.368778846903987 0.205500237175154 823.807933239872 462.174013578028 1.78246268513059 0.0756277685052754 200.848694585595 1094.31349052631 0.1835385347292 0.854492457026565 RPL38 essential 1 1 1 1.78246268513059 0.1835385347292 0.0102817495081566 16.3675201393117 7.20238282102699 2.27251460329594 0.0237289913574305 -57.8967187197673 33.9648012517625 -1.70460937753207 0.0892533134233605 CYP7B1 other 1 1 1 2.27251460329594 -1.70460937753207 0.0515856866988457 53.8596737825413 88.5606934394944 0.608166802796535 0.543512331664821 -1041.34652063994 462.039724364087 -2.253803008114 0.0248913705349347 OVOL1 other 1 1 1 0.608166802796535 -2.253803008114 0.00197152149758184 253.314928395318 140.214653355362 1.80662236316567 0.0717663669834136 -996.134277139612 380.472147394333 -2.61815295537833 0.0092637702033709 RARG og 1 1 1 1.80662236316567 -2.61815295537833 0.00505762584114853 16.5716729477836 8.19101866365173 2.02315165283674 0.0438885945852425 -33.7091404714268 22.0658915631767 -1.52765821289905 0.127585229704377 CES4A other 1 1 1 2.02315165283674 -1.52765821289905 0.710156833428986 5.92451223236861 13.1078559615458 0.451981792426557 0.651588308895278 28.8742197937927 35.3114234199854 0.817701950169775 0.414135816301112 CES3 other 1 1 1 0.451981792426557 0.817701950169775 1.19715456073367e-14 360.911326195465 45.8436534500143 7.87265627921617 5.92411335543704e-14 -390.883196673894 253.702317169082 -1.54071591081837 0.124409357164404 SSH3 other 1.63662999997901e-10 1 8.45311734687312e-10 7.87265627921617 -1.54071591081837 4.59551623432408e-05 470.285078837998 207.889374730044 2.26218910633932 0.0243561030852797 -1493.9724568204 560.035886657919 -2.66763700757796 0.00802742767526837 CES2 other 0.411942075244811 1 1 2.26218910633932 -2.66763700757796 4.45974448902622e-05 54.5302676280523 14.1851934079387 3.84416807440459 0.000145923175781609 -24.6480823644805 38.2136767593102 -0.645006826213742 0.519384913470313 PDP2 other 0.400172873000323 1 1 3.84416807440459 -0.645006826213742 4.71962430142483e-10 394.747845632031 63.6623576086137 6.20064761124431 1.78090085638724e-09 -467.732194344817 238.826996558747 -1.95845612549821 0.0510672079549409 SP3 other 5.78153976924542e-06 1 2.35417284205829e-05 6.20064761124431 -1.95845612549821 0.36072416565554 149.960470677943 111.811409323271 1.34119113233225 0.180812516417128 -66.9399611141175 303.52501290785 -0.22054182774861 0.825590281010022 KRT2 other 1 1 1 1.34119113233225 -0.22054182774861 5.80973518794564e-07 64.6130512755405 37.786189974204 1.70996470720257 0.0882417301274671 -233.265746770801 56.4254532265444 -4.13405180520669 4.55767012310298e-05 DMXL1 other 0.0061135843382752 0.658264295879764 1 1.70996470720257 -4.13405180520669 6.63925967336513e-13 32.5572594924089 4.49654290476911 7.2405090270301 3.44529117144295e-12 -34.2579444233321 16.4527170969854 -2.08220588863155 0.0381304469721677 METAP1D other 8.78042091802539e-09 1 4.79997966005432e-08 7.2405090270301 -2.08220588863155 1.44230740471642e-09 39.1560082362114 20.1932373121544 1.93906542229577 0.0533722183258377 -124.289454850769 28.9255958488398 -4.29686757362871 2.30123044206637e-05 ZNF621 other 1.73235542380489e-05 0.335473373844436 1 1.93906542229577 -4.29686757362871 8.58825514758961e-07 298.423259996484 57.5340867522319 5.18689487992799 3.82797356116436e-07 258.572019263454 120.22269158699 2.15077549712285 0.0322519892117486 EGFL7 other 0.00893522065555223 1 0.00465137067417081 5.18689487992799 2.15077549712285 8.73237738907438e-51 506.71838495792 27.8942206484287 18.1657122220571 5.36743888401335e-49 -74.7406134944251 187.908015221836 -0.397751066691804 0.691122268658556 NADSYN1 other 1.33858612997121e-46 1 8.22667357752726e-45 18.1657122220571 -0.397751066691804 2.51168178894731e-27 621.093177870714 52.7161647952747 11.7818354252961 3.38914382864325e-26 -549.598480356402 465.944614163904 -1.17953607284979 0.239207912398828 DHCR7 other 3.77229487881997e-23 1 5.11794609563416e-22 11.7818354252961 -1.17953607284979 0.161514218234445 -8.10574876333523 7.4229885183562 -1.09197915951111 0.275663710454256 11.1638926003957 10.9698828842769 1.01768566885951 0.309596162375717 LVRN other 1 1 1 -1.09197915951111 1.01768566885951 0.923830068070372 5.41176877822078 14.8136394888968 0.365323375277024 0.7151128969337 7.94618060534941 25.9613033667509 0.306077876487751 0.75974563748435 NBEA other 1 1 1 0.365323375277024 0.306077876487751 3.96470163894956e-05 162.902706308815 36.2021549906483 4.4998068858303 9.55161833199679e-06 -24.9537743451774 182.650051738065 -0.136620680408911 0.891417080996461 RNASEH2C essential 0.357853969931587 1 0.107398396524972 4.4998068858303 -0.136620680408911 3.94151283906623e-07 45.6420661448007 8.38269949755077 5.44479331009495 1.18965185371588e-07 -51.7402573530398 117.008878989762 -0.442190864486164 0.658714502366998 MYEOV other 0.00419849947617335 1 0.00147659588083215 5.44479331009495 -0.442190864486164 8.25307235891477e-12 217.229535061469 29.7611337844719 7.29910146013358 2.46555526917387e-12 -20.1143115649292 164.536591121662 -0.122248257532309 0.902781875381732 ANKRD13D other 1.06382102706411e-07 1 3.44364104445515e-08 7.29910146013358 -0.122248257532309 3.71555477970804e-08 26.5994109832949 4.43427078763434 5.99859870025789 6.13291101968436e-09 16.8612765303579 60.2791241863884 0.279719998555741 0.779898855499414 MRGPRF other 0.000419374667985647 1 7.98382356542511e-05 5.99859870025789 0.279719998555741 4.85448009725847e-13 250.114197469166 96.4893444762148 2.59214319287681 0.00997547317321537 -679.227269456049 138.215172678555 -4.91427428908775 1.42541272078643e-06 MYD88 other 6.436555160955e-09 0.0213127710011988 1 2.59214319287681 -4.91427428908775 1.22569696276863e-19 489.489599784099 79.332393656928 6.17011005492777 2.0611604086477e-09 -383.966781280611 113.638874300761 -3.37883302385053 0.000817921935415105 OXSR1 other 1.77505434148153e-15 1 2.72073173941497e-05 6.17011005492777 -3.37883302385053 2.20567675253575e-07 122.714189758053 24.0491816486518 5.10263474037721 5.7539706488957e-07 -138.340341643625 83.6151201031519 -1.6544895405635 0.0990085570286138 LCLAT1 other 0.00238830678764571 1 0.00693583622017887 5.10263474037721 -1.6544895405635 0.222274232339586 24.0603782000045 40.8984003996344 0.588296313912061 0.556748391358738 -207.741566671093 136.056027378506 -1.52688249593793 0.127778007164985 MIR4435-2HG other 1 1 1 0.588296313912061 -1.52688249593793 1.1389811275127e-20 258.574794020957 25.8062830156023 10.0198387293755 1.02193621303066e-20 -120.685713219011 130.020656668333 -0.92820415087478 0.354005668046055 KAT5 essential 1.66086228013903e-16 1 1.52176521482396e-16 10.0198387293755 -0.92820415087478 0.000361503000310151 69.1132519395301 17.1458740644999 4.03089697728664 6.9546302275777e-05 37.1741678670904 55.7689732722015 0.666574363591883 0.505525851574583 SH3RF3 other 1 1 0.732948479684414 4.03089697728664 0.666574363591883 0.0289652579784677 74.9024857565738 29.609592869951 2.52966955964423 0.0118996837174523 26.5470691997323 41.3693609560942 0.64170846699583 0.521524762973847 GXYLT2 other 1 1 1 2.52966955964423 0.64170846699583 0.00562354095002904 84.5108483482621 39.3233265095923 2.1491276514373 0.0323763257196938 -213.999216337041 95.4950002597318 -2.24094681140369 0.0257172304032409 DCAKD other 1 1 1 2.1491276514373 -2.24094681140369 0.253298421749432 27.1619137924924 24.6954072119539 1.09987713745188 0.272212391417289 59.9408156392901 36.7987265503168 1.62888287879554 0.104321834644498 ARPP21 other 1 1 1 1.09987713745188 1.62888287879554 6.71280539338499e-24 142.683911619157 20.4999871416894 6.96019517636628 1.9397584851905e-11 -126.3859633389 38.0368538362136 -3.32272390043394 0.000995032758774776 TADA2B other 9.95710424000796e-20 1 2.66949562731916e-07 6.96019517636628 -3.32272390043394 0.108285006094125 6.18411441302639 6.29977394486357 0.981640685388167 0.327020798007804 -11.5026103727679 11.688962489867 -0.984057428770037 0.325833039701483 CCDC96 other 1 1 1 0.981640685388167 -0.984057428770037 6.7897148441741e-14 514.940202555363 64.3537283464716 8.00171514201937 2.49708212488816e-14 -132.929460983057 375.631200723944 -0.35388290623054 0.723667981099267 GRK2 other 9.15660943885319e-10 1 3.57607131105234e-10 8.00171514201937 -0.35388290623054 7.35231726029358e-31 646.719522079795 50.6922663496635 12.7577551498462 2.03915857216668e-30 -341.718782636997 253.880495249934 -1.34598281093075 0.179260831302641 RELA other 1.11255264782762e-26 1 3.09911319797891e-26 12.7577551498462 -1.34598281093075 0.00195626991381177 37.1402241867681 12.1277173471004 3.06242494970811 0.00238299371391565 4.58124157036038 22.4235317216229 0.204305085712378 0.838245788642403 EVC2 other 1 1 1 3.06242494970811 0.204305085712378 0.027882386986529 9.96469060157245 7.36244464284753 1.35344862813372 0.176941517312052 -53.4946365292035 28.0110023361821 -1.90977230615214 0.0571257354763025 ZNF680 other 1 1 1 1.35344862813372 -1.90977230615214 2.92248346874451e-26 210.799320106461 18.3352995732408 11.4969116956294 9.10168954019626e-26 -99.4945625799315 58.3846546604323 -1.70412179636235 0.0893476036515031 FAM222B other 4.37466550436366e-22 1 1.37353596851102e-21 11.4969116956294 -1.70412179636235 0.309708659117968 9.72234613827716 15.7457189870252 0.61745965022547 0.537374865984647 86.8297240531955 58.6925650086172 1.47939903530281 0.140026741541672 BNC2 other 1 1 1 0.61745965022547 1.47939903530281 0.0515873060996682 4.70270429270743 5.86013167784246 0.802491232490332 0.422866306851053 27.9919915885154 11.7795515488025 2.37632064960582 0.0180762141870371 DEC1 other 1 1 1 0.802491232490332 2.37632064960582 0.0467332210225579 38.7577115739518 38.2544739626915 1.01315500016419 0.311758804220622 -117.999349679234 71.7933898148658 -1.64359629742404 0.10125101597957 HPSE other 1 1 1 1.01315500016419 -1.64359629742404 0.00313382960947784 9.93449434142802 15.0013016370392 0.662242156167241 0.508297194967582 -78.3066848287785 28.1534206223487 -2.7814270201546 0.00573601117580383 COQ2 essential 1 1 1 0.662242156167241 -2.7814270201546 0.460016674765625 107.682060219202 126.452420615246 0.85156187359073 0.395094116028698 -406.567723490073 434.140861961124 -0.936488036748036 0.349728180344386 HSPA6 other 1 1 1 0.85156187359073 -0.936488036748036 4.23198004950785e-10 624.284686312898 102.419306998753 6.09538088673553 3.16763060130365e-09 -517.174905032047 398.205351215788 -1.29876432713178 0.19496875663933 TRMT112 essential 5.19136992673128e-06 1 4.15878221645156e-05 6.09538088673553 -1.29876432713178 0.45229163092128 0.31823735097106 1.87320708367351 0.169889038827982 0.865206804376962 -6.03368861552288 5.26909375821047 -1.14510936650558 0.253035901663504 LRRN3 other 1 1 1 0.169889038827982 -1.14510936650558 1.26323288495734e-24 901.725575037553 83.3172418786626 10.8227967549714 2.32970486258822e-23 -975.823868500545 486.320783768626 -2.00654362525622 0.0456692642135123 KDM2A essential 1.880069502682e-20 1 3.4964210577724e-19 10.8227967549714 -2.00654362525622 0.000129636699389168 53.4334548629683 12.9551983436932 4.12447987637183 4.74135897552105e-05 -43.7526770759411 63.8432779341209 -0.68531376351147 0.493642080080031 ADCK5 other 1 1 0.507230583201242 4.12447987637183 -0.68531376351147 2.78107978538927e-06 67.6304106316516 33.4679760743416 2.02074993962664 0.0441678717018364 -174.598840608764 54.1689716336579 -3.22322605253737 0.00140297794546016 MRPL57 other 0.0277996735347512 1 1 2.02074993962664 -3.22322605253737 5.78724208898262e-08 91.428426798247 23.4230061139255 3.9033600705885 0.000115772465824356 -91.8724988727074 43.3973672752137 -2.11700627575121 0.0350330657008905 NOC3L essential 0.000646434941339359 1 1 3.9033600705885 -2.11700627575121 2.54304307206192e-08 162.514845541107 47.702985608829 3.40680658593891 0.00074199315029404 -734.237643288653 185.468782156832 -3.95882064221344 9.30295358943842e-05 ESRRA other 0.00028957631461569 1 1 3.40680658593891 -3.95882064221344 2.36914149184757e-10 855.568149707772 133.122354073951 6.42693074096703 4.92589774500541e-10 -1301.53292786457 809.973446193917 -1.6068834527607 0.109101275908564 RHOD other 2.93204951031055e-06 1 6.60464369650325e-06 6.42693074096703 -1.6068834527607 0.0278638338788697 9.42461767411007 3.50312130194896 2.69034865246222 0.00751840141124389 4.00226444284666 9.40175789605336 0.425693204089707 0.670622113940558 ADAMTS20 other 1 1 1 2.69034865246222 0.425693204089707 0.778046536040875 -24.3230833633217 41.6960993239812 -0.583341937439517 0.560075318410471 -76.8019432591817 178.532031146554 -0.430185792241037 0.667350966347707 COMMD1 other 1 1 1 -0.583341937439517 -0.430185792241037 1.18462974878481e-09 305.060296798617 53.3046254144165 5.72296108315043 2.43191218191566e-08 -133.115886566186 115.760826601122 -1.14992170041135 0.251045637294297 RAPH1 other 1.42700499538619e-05 1 0.000310190398803343 5.72296108315043 -1.14992170041135 6.32495800667422e-07 120.624517315471 22.2972211460567 5.409845313249 1.2427601124745e-07 42.3645998210725 78.1632852721449 0.54200126918373 0.588197206974432 MTX1 other 0.00664056312928244 1 0.00154151964351337 5.409845313249 0.54200126918373 0.512363715935841 25.2309466125069 21.9193913442224 1.15107879668188 0.250559179901959 7.55736488920686 86.1823365578217 0.0876904153571706 0.930177586623421 ADCY5 other 1 1 1 1.15107879668188 0.0876904153571706 0.0380226749841437 202.281116013086 144.552731428975 1.3993586562733 0.162674050736485 -1062.94652943019 569.087407699715 -1.86780890782083 0.0627025921749871 PARP14 other 1 1 1 1.3993586562733 -1.86780890782083 0.358692592298061 -2.66423355603917 3.18175965386046 -0.837345948744629 0.403023063734746 -16.2409033558297 12.5262202619026 -1.29655259258254 0.19571935692337 PARP15 other 1 1 1 -0.837345948744629 -1.29655259258254 0.183543518159975 66.1011646302466 42.0371644580709 1.57244584601271 0.116838459964067 134.30526103201 148.706666199939 0.903155618131023 0.367124788364428 CKS1B other 1 1 1 1.57244584601271 0.903155618131023 0.137510346370504 -5.17516871332161 2.60609882303849 -1.98579143184133 0.047939973244192 -4.16396649162003 7.11184314642776 -0.585497515325766 0.558640587003709 ABCD2 other 1 1 1 -1.98579143184133 -0.585497515325766 0.000816475321440203 164.722921381026 48.3870664588609 3.40427584137746 0.000748100824585197 389.986870371106 207.080611229455 1.88326115156663 0.0605745865816819 AHSA2 other 1 1 1 3.40427584137746 1.88326115156663 0.925919049378503 15.5442065730592 40.3012180822017 0.385700663968864 0.699974651622928 3.65365931744926 58.5641171815011 0.062387337046777 0.95029332800921 ABLIM3 other 1 1 1 0.385700663968864 0.062387337046777 0.132651853310723 4.70047092374226 9.05442381907228 0.519135288745946 0.604026371661993 -25.1225808872503 16.64117274232 -1.50966408895938 0.132118989302555 MAB21L3 other 1 1 1 0.519135288745946 -1.50966408895938 1.23287986657307e-05 17.9780510807881 5.99062097965077 3.00103297168304 0.00290287560117731 -40.7111669581496 13.7193145121127 -2.96743448240113 0.00323003465834132 MFSD4B other 0.116712483056802 1 1 3.00103297168304 -2.96743448240113 1.13309794713617e-10 209.361060573628 65.5981072585085 3.1915716675876 0.00155589477789569 -483.87714041096 119.609569885453 -4.04547178686753 6.55564178019767e-05 VANGL1 other 1.41331306946295e-06 0.941849054561 1 3.1915716675876 -4.04547178686753 0.00165083696496068 28.0593269877586 27.9324468174923 1.00454239369344 0.315878615250556 -109.748537711924 39.6909405414147 -2.76507777882988 0.00602216024832173 GLRX other 1 1 1 1.00454239369344 -2.76507777882988 1.37837487182683e-09 163.647071140471 25.0995381427888 6.51992360215948 2.75066622871298e-10 17.0194992887003 98.3484353757902 0.173053076275882 0.862719458517809 IQCB1 other 1.65653092096148e-05 1 3.70487234345352e-06 6.51992360215948 0.173053076275882 6.90872029051874e-08 97.9499195845522 17.0414638010377 5.74774096451665 2.17511648212397e-08 -59.3704729978494 107.490423434095 -0.552332673935838 0.581121028417238 SYT12 other 0.000768111521899873 1 0.0002779363840858 5.74774096451665 -0.552332673935838 8.74493535205848e-14 803.682096109812 100.494788148858 7.99725150840018 2.36697895359724e-14 -13.87394603268 393.772392210382 -0.0352334148029034 0.971915654090538 GOLGB1 other 1.17698084903355e-09 1 3.39046065313268e-10 7.99725150840018 -0.0352334148029034 0.000937801754830817 7.61915084764987 4.42761636970886 1.72082452756648 0.0862553611345356 -20.7451753404245 8.89520324610642 -2.33217552949169 0.0203153503598688 LIPM other 1 1 1 1.72082452756648 -2.33217552949169 0.127928675903933 13.7647590161315 9.90947155007747 1.38905076285565 0.165801645107108 53.8800831622858 31.6307718712927 1.70340715621885 0.089481337504262 DMRT2 other 1 1 1 1.38905076285565 1.70340715621885 1.44835378410608e-08 21.6937789333797 3.51746716657643 6.16744319307872 2.09245545317657e-09 24.1821796573254 18.8925477714305 1.27998510046876 0.201477512104562 SLC2A14 other 0.000166748971164133 1 2.76120421601181e-05 6.16744319307872 1.27998510046876 0.0361945893188578 54.0137378587458 48.1871625899345 1.12091550852235 0.263174950466005 -373.919518586514 190.778425034318 -1.95996753049644 0.0508781514078594 GPR137 other 1 1 1 1.12091550852235 -1.95996753049644 0.0730338466938362 -29.9583923230179 63.7854274542583 -0.469674556065358 0.638910458458408 -292.553332681228 130.227992277045 -2.24647042134271 0.0253619836370181 SNCG other 1 1 1 -0.469674556065358 -2.24647042134271 0.0316275217893252 48.2516976158731 35.257241399098 1.36856134232633 0.172105524953401 -108.967520065073 71.9832090789745 -1.51379080565194 0.131075272036368 MMRN2 other 1 1 1 1.36856134232633 -1.51379080565194 3.67268576610758e-24 186.967003524231 43.9633190620114 4.25279545569589 2.77692996838996e-05 -453.178547710292 85.1627502606688 -5.32132354020026 1.94474468649323e-07 TNKS other 5.4554074369762e-20 0.00293384183404368 0.302048517457913 4.25279545569589 -5.32132354020026 0.0361838115868546 32.0251090323601 25.4083357564416 1.26041742124889 0.208437119599594 -64.8727885608231 41.186457563129 -1.57509998186634 0.11622146225914 ZBTB21 other 1 1 1 1.26041742124889 -1.57509998186634 0.00640212584307211 133.189394796601 58.3781211584623 2.28149505591436 0.0231777608347368 -29.2996310393478 113.086124045652 -0.259091301312262 0.795731906283237 PPP1R3B other 1 1 1 2.28149505591436 -0.259091301312262 7.05952507019004e-09 11.0637042465726 3.75683988146207 2.94494963737099 0.00346747341720221 -17.3803201836882 7.2774945891366 -2.38822852711323 0.0175111607938401 FAM86B3P other 8.25187885454514e-05 1 1 2.94494963737099 -2.38822852711323 0.0251235917920757 35.6970575256268 23.536246220731 1.51668440204303 0.130339809279895 -63.0864647138103 43.9343476511876 -1.43592583221399 0.152006391568068 STOX2 other 1 1 1 1.51668440204303 -1.43592583221399 5.88577559238885e-21 538.11789485641 52.7185383607856 10.2073750826272 2.53976917388272e-21 -130.633464367284 262.792486488952 -0.497097409871253 0.619467131974224 MAP3K11 other 8.59794098536164e-17 1 3.79111344585473e-17 10.2073750826272 -0.497097409871253 5.09798189530785e-07 357.720261510971 71.6427692402134 4.99311047443685 9.87198955031431e-07 -842.896772883276 426.565448743136 -1.97600807887007 0.0490289286391337 TRIB1 other 0.00538601787239274 1 0.0117753091356149 4.99311047443685 -1.97600807887007 0.0219124531627723 38.1607646659001 16.1180583160944 2.36757827261335 0.0185088241345443 -81.703243695465 77.8694679227875 -1.04923336289493 0.294875057078679 KCNK7 other 1 1 1 2.36757827261335 -1.04923336289493 0.00206832532660391 31.0086293146573 13.5002078354735 2.2969001435058 0.0222760369564435 -87.7253314157083 37.9682928402764 -2.31048922280356 0.0215027617640184 SFT2D3 other 1 1 1 2.2969001435058 -2.31048922280356 0.514392861321534 -329.344254264244 298.415081514773 -1.10364480438614 0.270576480078938 -373.398658409321 576.954734920379 -0.647188827492422 0.517973724277302 C1QB other 1 1 1 -1.10364480438614 -0.647188827492422 0.254871841137737 -385.176694419001 256.25233090687 -1.50311489091971 0.133795637059648 -548.939216007946 495.437411878205 -1.10798902716473 0.268698649553452 C1QA other 1 1 1 -1.50311489091971 -1.10798902716473 0.434562344333744 4.17387844567015 4.27707189953102 0.975872873712462 0.329866909664512 8.76536386781272 7.71722099438633 1.13581869356713 0.256885057555911 NDNF other 1 1 1 0.975872873712462 1.13581869356713 0.617167813038399 19.5318081810425 23.5181560173688 0.830499132951483 0.406875820605415 -45.1773037245746 123.223769219286 -0.366628159573485 0.714138698862346 OLR1 other 1 1 1 0.830499132951483 -0.366628159573485 1.707110515257e-06 549.711789846382 219.058162793548 2.50943303292678 0.0125876853711921 -795.942298662309 309.341033482388 -2.57302527796599 0.0105330180390127 DAG1 other 0.0173476570560417 1 1 2.50943303292678 -2.57302527796599 0.411377013100854 46.8229996995794 39.552563865447 1.18381705567471 0.237369634370392 -44.5675120168236 163.675863659072 -0.272291289750914 0.785574765682894 INSM1 other 1 1 1 1.18381705567471 -0.272291289750914 0.716222441580919 -1.57967557251907 10.5047782567354 -0.150376860311756 0.880562334581041 -20.5400970793229 25.1809455470744 -0.815699991921444 0.415280377049786 DAB1 other 1 1 1 -0.150376860311756 -0.815699991921444 0.00184847295129918 48.3941209296216 13.5118157588548 3.58161492084491 0.000394525505390053 -1.00829472413958 45.5877092950276 -0.0221176878534135 0.982367862023228 ARV1 other 1 1 1 3.58161492084491 -0.0221176878534135 3.55471346022597e-14 501.961233526355 64.5333167021478 7.77832690427406 1.04208163242504e-13 -193.158562590595 275.259419436851 -0.701732798048381 0.483360683144197 NAA20 essential 4.81272655379994e-10 1 1.48277795477759e-09 7.77832690427406 -0.701732798048381 0.0701557078319666 238.596683007631 342.426743577603 0.696781683915287 0.486446860722873 -1188.99538102887 716.433348440076 -1.65960362344623 0.0979769283932748 SAA1 other 1 1 1 0.696781683915287 -1.65960362344623 1.46177707531903e-05 -9.28992250426555 62.3080504119696 -0.149096664762294 0.881571275092356 -556.979912784283 120.82349176624 -4.60986439509532 5.83054583480478e-06 MINOS1 other 0.137567840558274 0.0863620449051284 1 -0.149096664762294 -4.60986439509532 3.16423508225945e-10 604.045733606471 94.7460719902392 6.37541716419336 6.48635247024043e-10 -651.099503317267 457.736662131756 -1.42243249707154 0.155890210633777 EHBP1L1 other 3.89991973888477e-06 1 8.6735505232055e-06 6.37541716419336 -1.42243249707154 0.0756119550605371 7.99594786313964 4.25328446436279 1.87994664597106 0.0610410257548583 -24.7001657803495 22.6524485251065 -1.0903971706623 0.276374273167631 THAP2 other 1 1 1 1.87994664597106 -1.0903971706623 1.4063452128203e-29 371.062228378903 51.5481198284272 7.19836590769842 4.39374768744466e-12 -358.068717050615 97.2449773319265 -3.68213070612807 0.000271541638540557 RNF26 other 2.12330000231609e-25 1 6.11214240800427e-08 7.19836590769842 -3.68213070612807 7.15269682733392e-11 655.623251057865 104.552992909714 6.27072676555536 1.17937445880448e-09 -647.323670019405 413.937120342214 -1.56382126223481 0.118860412431469 PPP1R14B other 8.9923704513242e-07 1 1.56668103107588e-05 6.27072676555536 -1.56382126223481 7.20931685393912e-14 389.775528645454 49.1730303155607 7.92661192820794 3.90307422584275e-14 -152.530843338337 237.733058477435 -0.641605523082164 0.521594455024973 SSSCA1 other 9.71815911910993e-10 1 5.58022522068738e-10 7.92661192820794 -0.641605523082164 0.793845795253747 -5.86409713205311 9.08437402563116 -0.645514717415622 0.519057710854974 3.61251069825866 38.6566612164842 0.0934511823984993 0.925603796131135 AGR3 other 1 1 1 -0.645514717415622 0.0934511823984993 1.32829003232495e-15 916.697751036599 192.941258384255 4.75117535105393 3.06283082509917e-06 -1033.05375888935 278.518550171776 -3.70910217022247 0.000245264367975229 SMARCC1 other 1.84260393284117e-11 1 0.0355349632328006 4.75117535105393 -3.70910217022247 0.0263864329933783 13.5343945270053 6.20611267639312 2.18081675804688 0.02992714339073 -15.3790815617149 16.3137286157602 -0.94270794396185 0.346543694064672 ZNF417 other 1 1 1 2.18081675804688 -0.94270794396185 0.895478345879186 8.8183781395852 19.1110206500436 0.461428947258505 0.644807345846588 13.9333062033511 83.0370089773655 0.167796340149355 0.866850499123499 PTPRM other 1 1 1 0.461428947258505 0.167796340149355 0.0970442870214306 117.980995046735 83.6518090970561 1.41038187123782 0.159410536663232 -403.96757886258 331.186970409861 -1.21975685928299 0.223466637902799 FKBP2 other 1 1 1 1.41038187123782 -1.21975685928299 3.201592643352e-07 232.016792573523 46.8138047244841 4.95616184027391 1.17806802043407e-06 -224.511942207961 185.119374329667 -1.21279548951015 0.2261196534126 VEGFB other 0.0034353089063167 1 0.0139978042187976 4.95616184027391 -1.21279548951015 0.384692342496361 51.0892087244606 41.9244645731228 1.21860134040241 0.223895965742735 -12.6098221343441 81.2787600219384 -0.155142895031131 0.87680678457355 PEAK1 other 1 1 1 1.21860134040241 -0.155142895031131 0.0700489628146398 32.8402112778336 29.0325904557154 1.131149882334 0.258841674292913 -46.1738668734342 53.6694507566818 -0.860337980404721 0.390248893285923 TNFRSF10D other 1 1 1 1.131149882334 -0.860337980404721 4.85658740546993e-07 10.4464807491594 9.33785604917519 1.11872368712325 0.264099745286836 -52.3764968610702 13.1863702494573 -3.97201776305543 8.81391072217915e-05 MST1 other 0.00513972645120883 1 1 1.11872368712325 -3.97201776305543 1.91314169155858e-25 125.872675289358 40.6628661145757 3.09551901567111 0.00213884995849595 -452.834204207345 57.4217042078165 -7.88611571973691 5.00177563111667e-14 GMPPB essential 2.85708580217359e-21 7.67422435082231e-10 1 3.09551901567111 -7.88611571973691 5.21763635849242e-09 135.927098695137 24.1703080776563 5.62372222391288 4.07676188632248e-08 -47.2702300883535 53.9088919681056 -0.876854046941277 0.381223709031438 MOB1B other 6.13646212122293e-05 1 0.000515343470050024 5.62372222391288 -0.876854046941277 3.88962064610526e-21 193.539921284378 18.5886764723931 10.411710676218 5.62383040820323e-22 -17.7760937506858 113.970458258325 -0.155971064978913 0.876157019774728 ZNF622 other 5.68779227079972e-17 1 8.41100075850876e-18 10.411710676218 -0.155971064978913 0.00232665689614965 1704.18268567966 503.196786477084 3.38671217996197 0.000795585659364931 363.706845514332 978.503726194555 0.371696944812672 0.710364497574725 CSPG4 other 1 1 1 3.38671217996197 0.371696944812672 4.81597083330251e-11 466.355455444219 83.9135736275625 5.55756876133134 5.76819076367742e-08 -349.721011004572 163.176209943086 -2.14321077273795 0.0328498880887275 SNX33 other 6.08738713329437e-07 1 0.000725061578994252 5.55756876133134 -2.14321077273795 0.210545928146236 71.8332969123353 43.2700172320899 1.66011713207875 0.0978859890838346 -25.4872249297726 113.156879971888 -0.225237961104128 0.821940211290891 NABP1 other 1 1 1 1.66011713207875 -0.225237961104128 0.000334591872385057 6.20475040372714 1.53242689657726 4.04896991666338 6.45871062253996e-05 2.30752718905864 5.33151288843489 0.432809080151363 0.665445030789549 ADGRF3 other 1 1 0.682556538590023 4.04896991666338 0.432809080151363 0.0399663851107115 -9.62639636486425 9.15490130013305 -1.05150192768592 0.293821515390631 -33.2261824547446 13.1351069426152 -2.52957076024607 0.0118999256059551 XCR1 other 1 1 1 -1.05150192768592 -2.52957076024607 0.000878213991111053 39.8981430488723 15.799340615563 2.52530431615425 0.012042458923395 -90.442754465202 43.7309353506342 -2.0681641894927 0.039427732879955 CCDC106 other 1 1 1 2.52530431615425 -2.0681641894927 0.0429807184072049 25.9809208088493 10.7245864838611 2.42255688347021 0.0159683530935124 -7.16519362655425 26.0902996872274 -0.274630560493791 0.783777854972491 CEP83 other 1 1 1 2.42255688347021 -0.274630560493791 0.32739506345004 -18.8451657545006 18.3500217756681 -1.02698329107648 0.305208866292574 -54.6610415897347 39.6192751694443 -1.37965778919376 0.168661366056324 SULT1B1 other 1 1 1 -1.02698329107648 -1.37965778919376 0.819590103395684 22.940241840599 37.4370760009153 0.612767990749014 0.540464981194219 23.0029719721508 91.1118853644871 0.252469498135494 0.800840277176885 NUDT4 essential 1 1 1 0.612767990749014 0.252469498135494 5.22958638224101e-10 540.256957183419 84.5810015364179 6.38745046014619 6.19021743463198e-10 -742.694583554719 534.372569487342 -1.38984413864513 0.165576679117748 PC other 6.39526118684254e-06 1 8.28127288405066e-06 6.38745046014619 -1.38984413864513 0.448124385882192 -9.72462695672736 22.99471430715 -0.422907057110233 0.672649813770761 48.2496483909866 49.6539522201368 0.971718186239751 0.331931626133142 UGT2A1 other 1 1 1 -0.422907057110233 0.971718186239751 0.00793731271508193 1.92386495072283 9.90689079590413 0.194194625776861 0.846147876086988 -59.9655988119983 19.466296829419 -3.08048312103068 0.00224766974182033 SCAI other 1 1 1 0.194194625776861 -3.08048312103068 9.78766382873655e-09 28.1993229459313 9.87468444539549 2.85571889429646 0.00457543552097124 -101.318533947127 22.3369563180869 -4.5359149431244 8.12944340541277e-06 NMNAT1 other 0.000113693503034604 0.119909290229838 1 2.85571889429646 -4.5359149431244 3.15414765658567e-11 221.247425691871 31.011079656881 7.13446381550856 6.94417885252553e-12 -50.8115563975632 195.924262160563 -0.259342849309404 0.795543414184414 LRFN4 other 4.00766001245776e-07 1 9.63088165056766e-08 7.13446381550856 -0.259342849309404 0.00995265076385535 472.305647375205 180.065622023774 2.62296401760046 0.00913410494702161 -123.595417110202 301.030181899082 -0.410574834491633 0.68165909486371 SLC19A1 other 1 1 1 2.62296401760046 -0.410574834491633 0.14127884050524 383.164826136082 194.628891909528 1.96869448506234 0.049850925346424 339.866258966339 389.0379027606 0.873607061303435 0.382987388659436 HSPB7 other 1 1 1 1.96869448506234 0.873607061303435 2.5438926844875e-25 197.49289614947 16.9834846538953 11.6285261931905 3.49245698958882e-26 51.7137106263952 104.417474910784 0.495259157249115 0.620768062023713 RCE1 other 3.79777738867139e-21 1 5.27326080858015e-22 11.6285261931905 0.495259157249115 0.0467819596808826 58.1922328651081 102.287269871193 0.568909825615519 0.569816401489373 -591.314166829569 259.577246042169 -2.27798921456123 0.0233862654285427 UQCRH essential 1 1 1 0.568909825615519 -2.27798921456123 0.0909338614943596 2.61205172981045 1.27487964326825 2.04886143064789 0.0412987002775198 6.37654949004128 5.08482529892318 1.25403511727171 0.210753195309708 SPDYE2B other 1 1 1 2.04886143064789 1.25403511727171 3.38813775874244e-14 266.153664744492 90.0016063770637 2.95721015944355 0.00333609438666703 -868.361420902766 157.307030611687 -5.52016917188095 7.02388173811182e-08 PSMD1 essential 4.59024903554426e-10 0.00106271330697632 1 2.95721015944355 -5.52016917188095 0.0213505245289396 -24.352997227516 17.7058293358408 -1.37542256652275 0.169962530673198 149.802091493826 70.3341162007573 2.12986384966067 0.0339455814071024 MUC13 other 1 1 1 -1.37542256652275 2.12986384966067 0.294955469713765 -2.37445747488878 20.1161386081572 -0.118037438553238 0.906112049782006 -42.2152367623875 29.937133387129 -1.41012956105334 0.15947266590096 SUSD5 other 1 1 1 -0.118037438553238 -1.41012956105334 0.0119998505959306 230.583438435853 82.7625364776716 2.78608472201745 0.00565315317976573 -184.572127182382 328.763468080359 -0.56141312859392 0.57490888388565 HEG1 other 1 1 1 2.78608472201745 -0.56141312859392 1.38632959794195e-13 125.934153346634 16.033615560903 7.85438274157685 6.63650277489123e-14 -70.2906605126949 98.5775113104216 -0.71304965583224 0.476351432356544 C11orf80 other 1.8579589271618e-09 1 9.46431660727239e-10 7.85438274157685 -0.71304965583224 2.2650489496999e-11 1086.32485582658 151.15556779956 7.18680014001931 4.69984667468845e-12 420.623915786494 485.417112214026 0.866520576227723 0.386853991900048 TOMM20 essential 2.88793741086737e-07 1 6.53419683181936e-08 7.18680014001931 0.866520576227723 4.96653262726696e-07 208.930776861339 96.9217987615864 2.15566342691677 0.0318551799527774 -597.671808098111 167.997784520083 -3.55761720194984 0.000430845838909769 AGFG1 other 0.00525260490659754 1 1 2.15566342691677 -3.55761720194984 0.000385823284480548 143.722893876723 36.3836915021215 3.95020098134745 9.60970520298e-05 -34.9842432783468 93.8730957268334 -0.372675930280912 0.709636366279326 STAT5B other 1 1 0.997583497121354 3.95020098134745 -0.372675930280912 0.000523052128541775 -89.1281631852806 27.6665076666813 -3.22151838819242 0.00140755963296666 91.5237382746666 61.9684078886406 1.47694190302804 0.140683942549815 CD7 other 1 1 1 -3.22151838819242 1.47694190302804 0.00011472124305621 265.319780151457 82.68172063667 3.20892910922061 0.00146729614492252 -556.460622886717 213.326046801294 -2.6084982646542 0.00952073694886727 CNP other 0.982128561804213 1 1 3.20892910922061 -2.6084982646542 7.61588534489657e-06 9388.10083194796 2055.06591295578 4.56827237158791 7.02864046825125e-06 -7938.94616801035 5302.249200321 -1.49727895994208 0.135306380733664 JUP other 0.0735161412342866 1 0.0797750693146517 4.56827237158791 -1.49727895994208 0.000734168763932974 103.831449800453 28.1511710265507 3.6883527758943 0.000265124154464814 -55.0237246704202 72.6324752518245 -0.757563672167954 0.449269718212753 HAP1 other 1 1 1 3.6883527758943 -0.757563672167954 0.2741549539773 34.1028328824769 28.0367769442205 1.21636067335146 0.224746804449683 -60.970478283739 84.8458291679409 -0.718603128541017 0.47291149411213 TDRD12 other 1 1 1 1.21636067335146 -0.718603128541017 9.43112053776236e-05 1397.44532997613 320.621028305953 4.35855794412403 1.76646651222225e-05 63.5922182577339 827.230202313184 0.0768736659758203 0.938772088081363 EIF1 essential 0.81475450325729 1 0.194858920963236 4.35855794412403 0.0768736659758203 0.0551049615299935 32.4772871601506 13.520415703559 2.40209235220494 0.0168729436954367 26.1614010716412 31.1575470885598 0.83964892991358 0.401734073975256 ENDOV other 1 1 1 2.40209235220494 0.83964892991358 0.0483245971908939 79.6774041982284 334.818352173599 0.237972033734031 0.812055086626461 -1807.47028400118 771.881597202101 -2.34164189242607 0.0198122605261134 RNF213 other 1 1 1 0.237972033734031 -2.34164189242607 0.229066267739057 -2.3206333550372 1.5626537076445 -1.48505925764913 0.138531340735512 -8.05616796334096 6.91499361785095 -1.1650289802935 0.244891556762705 TIGD3 other 1 1 1 -1.48505925764913 -1.1650289802935 2.59977225297374e-05 156.772737906838 37.0021838872184 4.23685094870823 2.96779000581796e-05 -109.328638288181 93.9115581349177 -1.16416594995809 0.245223983204037 PLK3 other 0.238893072325757 1 0.322212960931656 4.23685094870823 -1.16416594995809 7.41804390894796e-07 501.25380000577 207.904326881903 2.41098301090434 0.0164727659378328 -1312.58287585847 425.439951450684 -3.0852365213534 0.00221137711733239 NET1 other 0.00774888866728703 1 1 2.41098301090434 -3.0852365213534 0.159010117880814 56.4454084490858 33.3425468877941 1.69289432625043 0.091448835840238 -80.4759038740539 136.912495584098 -0.587790789516521 0.557087282662037 DPY19L1 other 1 1 1 1.69289432625043 -0.587790789516521 0.0738283351104011 -0.890143154588902 1.92557085244392 -0.46227494223811 0.644200288883007 10.1601103362662 4.59269163046468 2.21223438318201 0.0276608264891905 PHOSPHO1 other 1 1 1 -0.46227494223811 2.21223438318201 3.5648138356646e-06 50.3894321479073 20.0977511587127 2.50721743691521 0.0126781735336147 -156.017673515835 43.6686117352808 -3.57276467732966 0.000409219892537931 ZNF791 other 0.0353237741878661 1 1 2.50721743691521 -3.57276467732966 3.39798273578408e-24 351.179327318566 30.9588004299052 11.3434410391217 3.00437921695155e-25 -151.24352765475 221.925986773125 -0.681504360322465 0.496051552940043 PHC3 other 5.04804315228082e-20 1 4.52880123163277e-21 11.3434410391217 -0.681504360322465 5.23036960004165e-05 45.2114160680207 10.0247805679478 4.5099656557646 9.15072937667189e-06 -12.3174604760526 71.8619355024107 -0.17140451881705 0.86401540902691 GPR160 other 0.465764412883709 1 0.103055514240079 4.5099656557646 -0.17140451881705 0.317452544439768 63.2625824899557 50.4941103910566 1.25287052291866 0.211167576317962 128.674109057164 116.640537096248 1.10316800882858 0.270783128467059 CBX2 other 1 1 1 1.25287052291866 1.10316800882858 7.89109263322003e-07 651.359451127763 129.309958341394 5.03719481068963 8.0356568388284e-07 -1006.38697180772 803.333336341299 -1.25276386063002 0.211235832708642 SPTBN2 other 0.00823119872571182 1 0.00961787767039371 5.03719481068963 -1.25276386063002 2.78646258217109e-14 457.488729454278 55.526396007582 8.23912161329197 4.70904231376319e-15 361.857452853419 393.995226594999 0.918431058113769 0.359095939343554 GOLIM4 other 3.78262295529725e-10 1 6.78761359105827e-11 8.23912161329197 0.918431058113769 0.828766855618018 0.0753014202361299 0.123415225655298 0.610146923414854 0.542198887424805 0.0384379445953806 0.359916161531265 0.10679693968686 0.915017206603957 KRT28 other 1 1 1 0.610146923414854 0.10679693968686 3.34148217151095e-11 70.0863633360978 10.1169570545991 6.92761301227791 2.47983484607789e-11 -63.8693356722911 62.8512217352644 -1.01619879310087 0.310327174468415 RBM4B other 4.24201161673315e-07 1 3.40555719411876e-07 6.92761301227791 -1.01619879310087 0.968055549657783 2.7786019427766 12.3870931652571 0.224314284691902 0.822656364741535 -3.05213833417808 29.4481611635855 -0.103644445479069 0.917516643678576 HOXB2 other 1 1 1 0.224314284691902 -0.103644445479069 0.0168843994720363 141.483044095038 73.751077936043 1.91838611793217 0.0559544339764507 -298.674758332222 173.389705311011 -1.72256338861922 0.0859366997291455 C1QTNF1 other 1 1 1 1.91838611793217 -1.72256338861922 0.670748564461582 -5.33822745645774 11.0099545505181 -0.484854631503136 0.628111194895931 -14.3174409013417 16.3073067809841 -0.877977037755689 0.380614896751215 MARCH3 other 1 1 1 -0.484854631503136 -0.877977037755689 1.4916048682857e-07 14.6795752022545 3.76609459650219 3.89782434458454 0.000118397999323779 -22.1863895396001 7.94597888519732 -2.79215309531358 0.00555272818220667 SWSAP1 other 0.00163017496054944 1 1 3.89782434458454 -2.79215309531358 0.365660614948031 -27.9201822142997 21.0524774692246 -1.32621836337859 0.185713162688547 -29.4077698703082 29.8003736107066 -0.98682554301073 0.324473724469898 SLCO4C1 other 1 1 1 -1.32621836337859 -0.98682554301073 1.74855801427976e-19 449.184581028875 46.0793046341058 9.74807637822747 9.28286617372141e-20 -252.536917181621 294.40683683486 -0.857782108243889 0.39167547357606 RBM4 other 2.52666633063425e-15 1 1.37637056757767e-15 9.74807637822747 -0.857782108243889 0.623509672583234 -23.6417481654764 29.0687970585405 -0.813303285920817 0.416648905593296 -44.9192034104994 53.2713493189516 -0.843215048703846 0.399738021504742 PIFO other 1 1 1 -0.813303285920817 -0.843215048703846 4.69026987135592e-22 296.446880577745 28.1629959993591 10.5261130806002 1.90598950313502e-22 355.96851129823 175.927493434022 2.02338193053224 0.0438647266792051 XXYLT1 other 6.89610379185461e-18 1 2.8546280301528e-18 10.5261130806002 2.02338193053224 0.000420999584046312 77.0042442283903 21.4355921999678 3.59235441269992 0.000379389545164225 -82.4847277746504 72.0767209776494 -1.14440177987881 0.253315002238644 UBXN2A other 1 1 1 3.59235441269992 -1.14440177987881 0.204651363721209 305.535748378694 565.211858456858 0.540568538694266 0.589188237744155 2447.48210878589 1415.61870404434 1.72891337320818 0.0848075046173016 TCAP other 1 1 1 0.540568538694266 1.72891337320818 9.03992896295448e-07 245.697135860802 45.5604608030818 5.39277108988728 1.37539506087912e-07 149.587063494283 291.31254299934 0.513493383958485 0.607970835658196 CCS other 0.0093924861925097 1 0.00170301416438053 5.39277108988728 0.513493383958485 0.0487207299465379 8.79009828341928 3.6354600647322 2.41787782753894 0.0161695548678474 -10.9463924771669 22.3144110338381 -0.490552605693584 0.624079115057452 NRROS other 1 1 1 2.41787782753894 -0.490552605693584 1.07884793766856e-07 37.2430639711136 6.41280999042605 5.80760447085058 1.52835513775104e-08 6.8517331479658 39.3617521469903 0.17407083715123 0.861919861203367 CEP19 other 0.00118824311854815 1 0.000196424202303764 5.80760447085058 0.17407083715123 4.92387202124506e-15 296.20644461179 34.7289731044217 8.52908733354045 5.96576714052608e-16 148.360229237869 213.166027637897 0.695984397147406 0.486943770925215 FBXO45 other 6.77229357802046e-11 1 8.65573154418929e-12 8.52908733354045 0.695984397147406 7.99541806547552e-12 165.323299744179 48.6051179243022 3.40135579964345 0.000755853025965227 -535.98069645391 102.95175085958 -5.20613483480192 3.46178286579561e-07 GNG5 other 1.03092920536241e-07 0.00521344499588818 1 3.40135579964345 -5.20613483480192 9.79490976530588e-17 75.1098175549451 12.7840287336763 5.87528541429879 1.0673599126139e-08 -95.0798896489839 23.9337390320199 -3.97262999825396 8.80378651144565e-05 SLC25A30 other 1.37647866931843e-12 1 0.000137838859114958 5.87528541429879 -3.97262999825396 0.463007852693139 31.8241392429143 35.9991204885615 0.884025465372862 0.377346163892969 -104.933638746221 122.009867357506 -0.860042232803604 0.390409629976491 CD34 other 1 1 1 0.884025465372862 -0.860042232803604 0.0148592485636955 231.222261627319 79.4400417982981 2.91065130874934 0.00386631847831625 68.9941061235521 486.506393558701 0.141815415042901 0.887317335331819 CTSF other 1 1 1 2.91065130874934 0.141815415042901 4.6948360696024e-05 105.797627387071 23.3232379283229 4.53614664105426 8.15566200796368e-06 53.8942069795833 108.857282588269 0.49509050472468 0.620881399320874 MSRB3 other 0.420375621672199 1 0.0921345137039657 4.53614664105426 0.49509050472468 3.56102939281884e-12 151.142067332487 20.2204084512785 7.47472869782367 7.71349742923534e-13 -35.178389371893 94.3753488943343 -0.372749767646208 0.709585374907034 LEMD3 other 4.6328992400573e-08 1 1.08405492870473e-08 7.47472869782367 -0.372749767646208 2.65333411897705e-06 49.4497723391641 13.6661939696289 3.61840117658647 0.000344384527339127 -93.8265857443935 37.9821409934137 -2.47028164527806 0.0140216654154501 C16orf91 other 0.0265704878674362 1 1 3.61840117658647 -2.47028164527806 0.12610165328377 -19.2895813342761 12.1204040232434 -1.59149656210174 0.112485211229288 -47.7326623588921 24.9201268754162 -1.91542613717511 0.0563292527163598 TLR10 other 1 1 1 -1.59149656210174 -1.91542613717511 0.233558732586823 -19.785212868037 16.0942013546045 -1.22933797285794 0.21984826960254 -54.6306725603971 33.0904431028951 -1.65095016680563 0.0997297725725329 TLR1 other 1 1 1 -1.22933797285794 -1.65095016680563 0.0101665365312216 -4.18223827079443 16.2771374857905 -0.256939420364631 0.797390663043778 -91.6743678548932 33.4665684853916 -2.7392819761282 0.0065025380470183 TLR6 other 1 1 1 -0.256939420364631 -2.7392819761282 0.0124469385894677 46.4310015290522 23.5631685146512 1.97049057728302 0.0496439112546632 -42.714952518912 33.5664240251902 -1.27254998884767 0.204101617888855 FAM174A other 1 1 1 1.97049057728302 -1.27254998884767 1.13106935306515e-05 68.2840433254308 41.0333967925623 1.66410896155221 0.0970695303402242 -203.657317513616 58.2422375172693 -3.49672894097225 0.000537565430220984 RGMB other 0.107383724380005 1 1 1.66410896155221 -3.49672894097225 0.00767619527262585 7.34650382121651 2.95279248418478 2.48798513968203 0.0133570741631649 -1.34476148281941 5.44875517312933 -0.246801597812861 0.80522052284022 FAM53A other 1 1 1 2.48798513968203 -0.246801597812861 2.88755503938968e-05 39.2792832897446 18.8838685807997 2.0800443045702 0.0383170098237123 -100.289299426854 35.077094811706 -2.85911076630513 0.00452713506631552 CYB561D1 other 0.264442290507307 1 1 2.0800443045702 -2.85911076630513 1.08255977625514e-10 97.5568077326665 13.9344929170017 7.0011021078231 1.55424282257992e-11 24.5736729086207 82.4547852868154 0.298026037217152 0.765881021256986 ZDHHC24 other 1.35146762467692e-06 1 2.14252373092642e-07 7.0011021078231 0.298026037217152 2.31819083384027e-21 181.229001744167 18.6188015126514 9.73365560726465 8.93819142613984e-20 -98.8749591050353 76.0836234039433 -1.29955639178865 0.19469140227767 TRMT10C other 3.39475865707569e-17 1 1.32544440658228e-15 9.73365560726465 -1.29955639178865 0.800606512853884 -2.63355097769979 11.4695815682408 -0.229611774590982 0.818540150539119 -22.4827625284018 36.3358074880161 -0.618749494856193 0.53652159710504 SELP other 1 1 1 -0.229611774590982 -0.618749494856193 2.86442367755349e-08 47.1790334466037 13.3591234100252 3.53159649765632 0.000473759814444046 -94.1422962416368 33.9900771851175 -2.76969939576533 0.00593834770887128 CTU2 essential 0.000325255308586199 1 1 3.53159649765632 -2.76969939576533 0.164236080147115 -47.5053553204132 62.809256951034 -0.756343214781992 0.450001633943123 -239.02015853254 125.401506715054 -1.90603896869961 0.057543726147929 MGA other 1 1 1 -0.756343214781992 -1.90603896869961 7.00131793830417e-08 45.2899385863817 7.89284540303882 5.73810030143814 2.23741080947948e-08 -20.2051541129231 32.4547637801601 -0.622563585727736 0.534018917199361 C12orf66 other 0.000778056462483742 1 0.000285672612154341 5.73810030143814 -0.622563585727736 0.76601121886245 -6.48190126368783 8.93104483794543 -0.725771886862341 0.468509081600635 -5.75402383955612 54.0967900312551 -0.106365346931521 0.915359134305383 SNX31 other 1 1 1 -0.725771886862341 -0.106365346931521 3.33715081971509e-22 194.609874212071 30.4826909713219 6.38427474776291 6.13962248003234e-10 -214.135373342812 56.4046027587765 -3.79641665519031 0.000175984746027649 PIGG other 4.91195229153864e-18 1 8.21481487828328e-06 6.38427474776291 -3.79641665519031 3.2821387976474e-14 1952.71843870139 249.121424575978 7.83842032866125 6.88136353048755e-14 -1080.27854516413 472.803666092548 -2.28483538228883 0.0229786640162387 PRPF8 essential 4.44828271245152e-10 1 9.8121362581222e-10 7.83842032866125 -2.28483538228883 0.170054590879217 -42.8346467034407 45.547774427173 -0.940433363477061 0.347709124514236 -206.192207852408 114.969905249116 -1.79344505334359 0.0738518559478203 ADCY6 other 1 1 1 -0.940433363477061 -1.79344505334359 7.2649225421839e-07 3.96948150333956 0.809463977530328 4.90383959450603 1.4976958233852e-06 -6.0899577235403 4.16138442164794 -1.46344511981631 0.14432717443846 REP15 other 0.00759184405658217 1 0.0176937784574728 4.90383959450603 -1.46344511981631 1.02237788475522e-08 380.868452726424 61.4594902635252 6.19706494624901 1.78112571848167e-09 -60.9321627319046 117.293374883366 -0.519485118341032 0.603783870713585 PITPNA other 0.000118606058410453 1 2.35429197468907e-05 6.19706494624901 -0.519485118341032 0.00102843529674452 178.876017861832 69.7600793872872 2.56416018205435 0.010801643673524 -380.154505300938 176.085655516517 -2.15891807987324 0.0316042038290733 DDX23 essential 1 1 1 2.56416018205435 -2.15891807987324 3.78390702110829e-05 64.9268372384529 16.5795403331074 3.91608186559923 0.000110235477940197 -106.450579651372 71.5724632673568 -1.48731194640778 0.137926422639432 ZNHIT2 other 0.342065194708189 1 1 3.91608186559923 -1.48731194640778 2.52014870781096e-13 493.285158849326 65.3165366957433 7.55222465555915 4.51445320700422e-13 -277.254380067793 124.676071370922 -2.22379785486614 0.0268597773446965 ZBTB4 other 3.36238240596139e-09 1 6.36131601398964e-09 7.55222465555915 -2.22379785486614 5.8344852266702e-12 174.508975861381 24.7155007142233 7.06070970922932 1.03548342192883e-11 -103.372931588117 47.176897105988 -2.19117699402482 0.029159655703647 TNK1 other 7.54982388331124e-08 1 1.43259131423854e-07 7.06070970922932 -2.19117699402482 4.43792174323121e-16 170.108885500416 19.9280327661108 8.53616046786613 5.79258492349073e-16 -46.0438306687612 90.8010559047534 -0.507084749290353 0.612446807235511 ZHX3 other 6.1940073770278e-12 1 8.40561998247739e-12 8.53616046786613 -0.507084749290353 0.013937743654433 323.714497874123 113.925142035586 2.84146670427681 0.00477963399433545 315.361288956567 379.805134764701 0.830323921639294 0.406976641430522 PHLDA3 other 1 1 1 2.84146670427681 0.830323921639294 0.00512682568091079 15.0291606241818 5.2157337026223 2.88150459380732 0.00422520208857389 -14.1863324803633 9.95578180130664 -1.42493404972992 0.155150830030397 SLC16A11 other 1 1 1 2.88150459380732 -1.42493404972992 0.0115271477701755 25.4614029762175 8.80982513001893 2.89011445748898 0.00411408557786657 -11.8714643532725 16.8161761514089 -0.705955042715098 0.480729722331116 SLC16A13 other 1 1 1 2.89011445748898 -0.705955042715098 0.237980586794871 16.53581082524 10.9514819326697 1.50991536368347 0.132057981691039 -11.0010254196934 26.498853465344 -0.415150996403707 0.678311327863692 GLIS1 other 1 1 1 1.50991536368347 -0.415150996403707 8.43841447536884e-05 26.4386179324834 6.90181914346392 3.83067382423676 0.000153875801915875 2.86493049952383 13.2170081332985 0.216760894041218 0.82853324733187 CHRNA9 other 0.732498675785125 1 1 3.83067382423676 0.216760894041218 0.977312413052673 8.13501371784507 40.3829614866095 0.201446684898099 0.840478109480983 11.4005666970508 97.7130022684912 0.11667399867343 0.907192045131051 PODN other 1 1 1 0.201446684898099 0.11667399867343 6.65601062378665e-07 32.4285568364078 6.66454038786526 4.86583544387448 1.80191512733834e-06 -47.2494335364123 34.0024570642437 -1.38958880080754 0.165632031187813 SNHG11 other 0.00697283669371327 1 0.0211652950857162 4.86583544387448 -1.38958880080754 3.61029698186523e-15 65.3229516493558 10.1134890527055 6.45899266899202 3.96176577469867e-10 -5.46524944727777 18.4780816358287 -0.295769309552174 0.7675999113329 C11orf45 other 4.97354512221753e-11 1 5.32183996515272e-06 6.45899266899202 -0.295769309552174 0.00812434115420529 63.9329217200146 21.3274723866811 2.99767926366842 0.00293411043246877 52.1806547664004 67.6221391170423 0.771650460156024 0.44089271309542 EXO1 other 1 1 1 2.99767926366842 0.771650460156024 4.77016202621847e-06 43.8876914552429 9.68767587004229 4.530260099944 8.41751969878001e-06 -35.1872542385048 31.2120744931331 -1.12736031840006 0.260462000788464 RALGAPA1 other 0.0468429910974653 1 0.0950253798795276 4.530260099944 -1.12736031840006 1.12465009419006e-15 80.8350355866691 11.2961642833532 7.1559720236889 5.83362473526884e-12 -86.654790576665 26.8275050036106 -3.23007266478946 0.00136785040773324 LIG4 other 1.56146419077348e-11 1 8.09707113255315e-08 7.1559720236889 -3.23007266478946 0.154129927364733 8.26340588010692 4.39694951655972 1.87934972848458 0.0611081917712676 -1.50618357487925 20.3658453364455 -0.073956349466323 0.941091470826736 MIR133A2 other 1 1 1 1.87934972848458 -0.073956349466323 0.0435575535885191 14.7435406642378 10.0471082196872 1.46744121212391 0.143250634995422 -55.5289792012051 35.3151691079946 -1.57238321672469 0.116862383145184 GTF2IRD2B other 1 1 1 1.46744121212391 -1.57238321672469 0.775045901174657 4.75314924341346 6.89753988553494 0.689107902569937 0.49125471101106 -5.69277260325213 37.8663246213982 -0.150338662655291 0.880592147873397 ABRA other 1 1 1 0.689107902569937 -0.150338662655291 0.0816881333977959 1357.17148549125 657.749933649607 2.0633548040983 0.0398851299487471 -1065.64073813783 1844.62277859887 -0.57770117039716 0.563872151422394 ATP2A2 essential 1 1 1 2.0633548040983 -0.57770117039716 0.0106558971904388 46.6885157129159 35.1249894832322 1.3292108097343 0.184725310355426 -142.643160104828 68.8402409804218 -2.07208978459846 0.0390577121463286 ZWILCH other 1 1 1 1.3292108097343 -2.07208978459846 2.63256646699211e-07 4210.35688445477 1016.34849579784 4.14263109736745 4.3988101738269e-05 -4157.12213100516 1991.90594503131 -2.08700724116761 0.0376785209225 RPL4 essential 0.00283895967800429 1 0.471772391142935 4.14263109736745 -2.08700724116761 0.000282550511841745 40.4057474302721 19.6424857138024 2.05705876633932 0.0404907455035484 -98.9177792714887 38.4966222022117 -2.5695184048071 0.0106365618390507 SNAPC5 essential 1 1 1 2.05705876633932 -2.5695184048071 0.0924217057956559 16.4742931487118 7.57570121438154 2.17462287417531 0.0303905644663328 1.23492205468948 21.2456289373822 0.058125935378482 0.953684595303606 C12orf76 other 1 1 1 2.17462287417531 0.058125935378482 4.4652200523616e-05 314.726088344949 83.0165773078687 3.7911233942804 0.000179511281247474 -40.4536225268452 185.019983920621 -0.218644611623148 0.827067594326804 CNTNAP2 other 0.400619543097883 1 1 3.7911233942804 -0.218644611623148 8.45789561636772e-07 75.9684344224602 14.4941109013145 5.24133111300884 2.93737835411105e-07 -53.3460954443903 85.5002493371526 -0.62392912135298 0.53312858555461 BBS1 other 0.00880297775751553 1 0.00358830139738206 5.24133111300884 -0.62392912135298 0.0436535103147739 38.9895632406145 32.5236773665528 1.1988054979512 0.231490583140105 -104.220500426714 63.742020152114 -1.63503604338241 0.103024752208244 DENND4A other 1 1 1 1.1988054979512 -1.63503604338241 0.411118681728452 7.69775128456786 7.97636521952709 0.96507006295585 0.335238470388195 -22.0795939644838 32.5189367140125 -0.678976504018646 0.497643520469568 GCSAM other 1 1 1 0.96507006295585 -0.678976504018646 0.691705966308749 -1.91574278003541 5.99754132296943 -0.319421355664275 0.749626407569119 -16.8111797003444 20.1832534224169 -0.832927147497077 0.405539710793374 ANKRD36C other 1 1 1 -0.319421355664275 -0.832927147497077 0.540049669802187 5.32212274801449 42.4603484804687 0.125343360063628 0.900330434275101 -158.874004600025 144.196700220423 -1.10178668691562 0.271382421806019 SLC26A9 other 1 1 1 0.125343360063628 -1.10178668691562 0.717720128383394 -34.0408633729651 43.4732062427616 -0.783030889943459 0.434188078849734 -35.2210195843136 147.636397546093 -0.238565964557063 0.81159486047653 MFSD4A other 1 1 1 -0.783030889943459 -0.238565964557063 1.45610207265754e-06 53.2270960947643 10.4310402813397 5.1027600947897 5.81686641267217e-07 -44.9967562948833 61.5323389597872 -0.731270045240597 0.465161314479915 PELI3 other 0.014894468101214 1 0.00700932402726996 5.1027600947897 -0.731270045240597 0.00141083302060715 8.73131519643147 2.6640493102482 3.27746005407761 0.00116254685966645 -8.46053752449101 7.47117679469396 -1.13242368063083 0.258304166004623 MYO1H other 1 1 1 3.27746005407761 -1.13242368063083 3.73761126789687e-05 11.4718866941405 2.52984187803788 4.5346259755325 8.16766526522934e-06 6.65720082737278 8.5914238565494 0.774865835806468 0.438991120975071 TMEM81 other 0.337954810843235 1 0.0922537791707654 4.5346259755325 0.774865835806468 8.77621018678534e-07 261.141464456666 49.8921712008962 5.23411706027288 3.04481054822445e-07 -183.342971926894 294.312159379273 -0.622954118897357 0.533768292530459 MRPL11 other 0.00912462573120072 1 0.0037155823119983 5.23411706027288 -0.622954118897357 8.29098541155262e-05 637.89489710076 166.197471589237 3.83817449808949 0.000149453542276885 -1261.0112118289 738.967881298508 -1.70644928384853 0.0888976758274945 IL20RB other 0.719989173139229 1 1 3.83817449808949 -1.70644928384853 3.41236600646031e-07 278.666044277202 51.1326391391065 5.44986624920904 1.01222366824458e-07 -49.4191984069368 128.002519584787 -0.386079887858788 0.69969567766565 AKIRIN1 other 0.00365737388572416 1 0.00126011724459768 5.44986624920904 -0.386079887858788 2.96277181651424e-14 248.894974748344 30.1643143877483 8.25130555095383 4.17478014906539e-15 7.69486238797934 134.695548020549 0.0571278152920499 0.954479145345102 MSL2 other 4.01929624628322e-10 1 6.02086793098211e-11 8.25130555095383 0.0571278152920499 0.00143777311986371 15.4815190819722 6.17254596628615 2.50812536132266 0.012643024621771 -27.7880103165998 15.7531414868539 -1.76396627553869 0.0787131360067035 ZNF497 other 1 1 1 2.50812536132266 -1.76396627553869 6.98386139500293e-06 16.7542552219545 3.37540323965092 4.96363072273617 1.12841616435013e-06 10.1532656487329 6.11342718381863 1.66081403171156 0.0977333084195145 TRAM1L1 other 0.0676107621650234 1 0.0134179966102873 4.96363072273617 1.66081403171156 0.0416668451601088 -32.0536473818528 19.9304486591231 -1.60827525411378 0.108761034469768 90.8415024972841 53.6254117727728 1.69400102477921 0.0912380995488546 CMKLR1 other 1 1 1 -1.60827525411378 1.69400102477921 0.0726015980939133 35.6973656086354 15.5860523267893 2.29034041848293 0.0226537977765946 -9.13037476399154 49.9228588128509 -0.18288966179239 0.855000774198197 ANGEL2 other 1 1 1 2.29034041848293 -0.18288966179239 0.223678929037912 14.6129613427586 38.1128222716033 0.383413257580933 0.701667969497358 117.696313862732 68.4941484187782 1.71834115146783 0.0867016563414773 UGT8 other 1 1 1 0.383413257580933 1.71834115146783 0.302650422251215 5.55729860894391 4.50325862883744 1.23406161337409 0.218085487908868 -14.5824147729082 18.900576450352 -0.771532805425978 0.440960535225202 KY other 1 1 1 1.23406161337409 -0.771532805425978 0.610172267968611 9.20717718251771 18.1114938556066 0.50836100301398 0.611551562710712 -37.3500895575767 55.1719215849097 -0.676976412722817 0.498911532633038 IQCK other 1 1 1 0.50836100301398 -0.676976412722817 0.140282752758204 70.2630311938249 71.3782828632349 0.984375476339956 0.325674609303798 -465.193519547627 292.181192194756 -1.5921405346226 0.112340435408046 SLCO2A1 other 1 1 1 0.984375476339956 -1.5921405346226 0.000151613133724866 84.4409401415376 27.8086005556071 3.03650447898975 0.00259005344656137 -107.626308482406 60.8272086040246 -1.76937773329426 0.0777832476120765 ZNF266 other 1 1 1 3.03650447898975 -1.76937773329426 0.996417598074145 0.860387249991916 15.5777239400643 0.0552318973748847 0.955988731664155 6.53265856732035 92.043406085977 0.0709736725868037 0.943463747117101 SLC29A2 other 1 1 1 0.0552318973748847 0.0709736725868037 0.074273591008058 -0.661954639344784 3.25061731922562 -0.203639670357284 0.8387645272112 -11.9341856207756 6.05058937653992 -1.97240051804676 0.04942457040146 BRSK2 other 1 1 1 -0.203639670357284 -1.97240051804676 7.71503222202102e-10 84.6926154800156 12.8483921048241 6.59168982305705 1.82288402088141e-10 -24.0532180092337 76.0630562071787 -0.316227340954038 0.75203873428341 B4GAT1 other 9.37299264653334e-06 1 2.4641746194275e-06 6.59168982305705 -0.316227340954038 4.27607031560773e-06 239.274637516884 70.9817349727808 3.37093250268732 0.000841202466024033 -207.778915432786 97.7460708028252 -2.1257009486542 0.0342960936254693 TMEM167A other 0.0421363968899986 1 1 3.37093250268732 -2.1257009486542 0.663467435049627 5.16011071903572 7.82254505215193 0.659646021164967 0.509958454760494 -4.57158505881947 18.0911447619039 -0.252697389744305 0.800665329216424 LEP other 1 1 1 0.659646021164967 -0.252697389744305 0.0488806327110809 295.983070134467 122.147340323071 2.42316426499023 0.0159404236238847 73.7515821746952 185.023340274404 0.398606911243284 0.690448708404982 SH3PXD2B other 1 1 1 2.42316426499023 0.398606911243284 1.36973522315803e-09 285.396054988266 44.0645083431444 6.47677838059138 3.64181427770027e-10 -106.968434697817 260.337813719302 -0.410883202749605 0.681440234177406 KIAA1551 other 1.64642173823595e-05 1 4.89496257065694e-06 6.47677838059138 -0.410883202749605 3.05171635842507e-05 98.8965171446648 32.1813192504413 3.07310326139935 0.00230174246043432 -128.438194468768 58.7965168159717 -2.1844524373913 0.0296589499584138 LARP7 other 0.278743772178546 1 1 3.07310326139935 -2.1844524373913 0.000504087268126594 10.5467812661955 2.7102527168317 3.89143831521538 0.000121339050920336 12.2333561301835 5.2558354659583 2.32757593144194 0.0205598919698006 FGFBP3 other 1 1 1 3.89143831521538 2.32757593144194 5.14582420811032e-10 70.498883046225 80.6510159379795 0.874122690536702 0.382706977053271 -680.468699152861 123.903017081442 -5.49194616226 8.11333163446514e-08 NR1D2 other 6.29591591862298e-06 0.00122697914308016 1 0.874122690536702 -5.49194616226 1.25921095364115e-12 763.146971405971 101.182866357806 7.54225491801453 4.94729153014771e-13 -425.143876258238 599.007096622432 -0.709747645153887 0.478384024548006 BRMS1 other 1.65535871965666e-08 1 6.96727066190702e-09 7.54225491801453 -0.709747645153887 3.99695820390134e-22 2352.0983592662 475.637205752014 4.94515216812649 1.23071602036587e-06 -4422.18721254284 730.714723720038 -6.05186548045682 4.00183625748564e-09 RPL15 essential 5.8783264304777e-18 6.09479662015062e-05 0.0146110605937837 4.94515216812649 -6.05186548045682 2.24529254123922e-05 300.686517130089 137.106001919431 2.1930952177191 0.0290198488075847 -534.649330100189 258.01286767644 -2.07218087576416 0.0390491613261571 HRAS og 0.207644654213803 1 1 2.1930952177191 -2.07218087576416 0.00014363989269758 17.8055917408835 4.17349473995574 4.26635058873283 2.63103783474664e-05 -1.55780544601492 29.4622884062022 -0.0528745569433427 0.957865372346699 WDR49 other 1 1 0.286783123987383 4.26635058873283 -0.0528745569433427 2.17455622342227e-15 542.384734007262 80.9666254836637 6.69886796895959 9.67010772381607e-11 -435.044569178035 172.109840895336 -2.5277146670689 0.0119694447281189 SRP72 essential 3.00849853510471e-11 1 1.3141676396666e-06 6.69886796895959 -2.5277146670689 6.6294324774819e-10 405.526217879158 64.0657469582957 6.3298445289827 8.40443513914553e-10 -537.530639646045 379.272088840913 -1.41726917287476 0.157389435448915 RIN1 other 8.06868226834323e-06 1 1.12073142580506e-05 6.3298445289827 -1.41726917287476 0.000384266724691605 25.1540995278724 8.10477087904975 3.10361636414595 0.00208396640516063 -21.8335590091569 16.9601439515988 -1.28734514703802 0.198913127680505 THAP6 other 1 1 1 3.10361636414595 -1.28734514703802 0.135561800834923 0.881469395245994 16.0750530585136 0.0548346180903681 0.956304982404895 -62.9470408211543 34.2610130307034 -1.83727903097155 0.0671105670127747 CEP135 other 1 1 1 0.0548346180903681 -1.83727903097155 0.00039715350390081 83.567002118644 23.1999423844073 3.60203489879395 0.00036673922492062 31.7581214689264 58.014993277891 0.547412309724926 0.584483132403428 FZD4 other 1 1 1 3.60203489879395 0.547412309724926 0.000397164750291288 326.841628766417 82.9485082773873 3.94029543814615 0.000100212573656198 -64.9809420656843 478.03433839568 -0.135933628290732 0.891960304125091 CD248 other 1 1 1 3.94029543814615 -0.135933628290732 0.440127285831856 -3.10944377538985 5.02030601053043 -0.619373354705386 0.536113918752648 -13.774926639584 10.850412416658 -1.26953023632873 0.205180293392906 BTC other 1 1 1 -0.619373354705386 -1.26953023632873 0.960033709784259 0.970178330585919 5.37185166689079 0.180604080445031 0.856798297679845 4.44812253533968 20.7121897595937 0.214758680128418 0.830098989888337 PDZK1 other 1 1 1 0.180604080445031 0.214758680128418 0.0307184069639615 -11.129316453816 10.8682791802065 -1.02401827090391 0.306600125811482 34.087795873781 19.580429380835 1.74091156076208 0.0826602146231069 ADGRE1 other 1 1 1 -1.02401827090391 1.74091156076208 6.88193757184548e-20 149.497103825222 35.0755231085574 4.2621489453638 2.66697799215213e-05 -273.281739714018 50.6280509732567 -5.39783251499004 1.31617049499642e-07 DENND6A other 9.97743309166158e-16 0.0019879439156426 0.290567252244975 4.2621489453638 -5.39783251499004 1.49184813390407e-14 109.203915123179 27.9837533793856 3.90240414295619 0.000116139642941801 -167.263683103788 40.4374141259933 -4.13635952542947 4.51440953679518e-05 PDE12 other 2.03503003945854e-10 0.6521967457808 1 3.90240414295619 -4.13635952542947 1.86984286409292e-08 24.5956769773557 8.56723432717386 2.8709004607639 0.0043658117932668 -76.4626203271035 18.1787796421822 -4.20614704793928 3.37649360948922e-05 GLMN essential 0.00021450837336874 0.489962987672981 1 2.8709004607639 -4.20614704793928 1.50687266542567e-20 625.329032678627 61.354028029462 10.1921430876282 2.80417335843951e-21 45.877922748675 353.584805876122 0.129750832010435 0.89684611555124 YIF1A other 2.19536278625866e-16 1 4.18522873747097e-17 10.1921430876282 0.129750832010435 0.0720617867127472 15.4885622307913 7.45070678036292 2.07880442585835 0.0384417698937368 55.3478917097482 42.9386104741073 1.28900053119148 0.198340698220969 CNIH2 other 1 1 1 2.07880442585835 1.28900053119148 0.0779544922732581 795.398088792147 360.40765838365 2.20694003107296 0.0280323516773206 232.454635230695 703.134842383402 0.330597520160924 0.741166230311809 AMY1B other 1 1 1 2.20694003107296 0.330597520160924 0.00111465598779885 276.054186829634 192.931211478983 1.43084255115304 0.153454194944902 -868.611463818172 349.998966596694 -2.48175436706097 0.0135882810951173 NDUFA11 other 1 1 1 1.43084255115304 -2.48175436706097 2.70746614205741e-14 176.719903868786 21.2635506564629 8.31093107279677 2.89792303256155e-15 45.3702488757852 123.229424225222 0.368177074274597 0.712989280572404 RSRC1 other 3.67673902091396e-10 1 4.18373148210911e-11 8.31093107279677 0.368177074274597 0.000203091337341979 6.75270121278941 1.63456662864941 4.13118749302313 4.63284123209901e-05 6.62704887908854 9.47286310553245 0.699582460472604 0.484706024951979 PQLC2L other 1 1 0.496038310720841 4.13118749302313 0.699582460472604 9.02020391382173e-36 1808.00981812895 127.991276336781 14.1260394448413 1.85425723139146e-35 -880.299359331146 737.616943025256 -1.19343701043619 0.233593480377909 RAB1B other 1.3729652377228e-31 1 2.82866940648768e-31 14.1260394448413 -1.19343701043619 1.39000231763784e-10 133.79148943033 32.4414641354775 4.12408912469576 4.74900548288633e-05 -128.501102492033 61.1974835806532 -2.09977755576632 0.0365311255276995 PTDSS2 other 1.73013588476382e-06 1 0.508001116504351 4.12408912469576 -2.09977755576632 2.70270017177706e-05 182.636316626275 68.3841198542985 2.67074164316813 0.00795889800536308 -281.407207137675 125.567418111995 -2.24108460115573 0.0257125614361948 C19orf70 other 0.248026794763981 1 1 2.67074164316813 -2.24108460115573 8.0271648343114e-14 23.4516436574303 2.94000598430439 7.976733306881 2.8089370024954e-14 29.8602013182553 16.7700161601385 1.78057081359477 0.0759462957722217 C3orf33 other 1.08101828823672e-09 1 4.02015063797142e-10 7.976733306881 1.78057081359477 0.617223075106843 81.1742583919053 83.8659874715715 0.967904401285698 0.333829985623593 30.7086635753273 303.677118377986 0.101122744246751 0.919516951782929 SEZ6L2 other 1 1 1 0.967904401285698 0.101122744246751 0.38718083717285 18.4428423773244 13.3796804103869 1.37842174189803 0.169045143278476 15.69906571575 48.4475639569853 0.324042416863076 0.746119618321302 ASPHD1 other 1 1 1 1.37842174189803 0.324042416863076 0.823405058100406 1.94107200576156 17.0122188226033 0.114098697295296 0.909231785028673 -34.3653915403153 61.6009152818373 -0.557871443680443 0.577325927062291 KCTD13 other 1 1 1 0.114098697295296 -0.557871443680443 0.477297329978444 -1.00619142326905 1.07003245423149 -0.940337294714776 0.347760557407576 4.79081962524195 6.61621419912237 0.724102860194194 0.46953663154015 P2RY14 other 1 1 1 -0.940337294714776 0.724102860194194 0.00482145040409443 6.91849276913667 3.03972933613864 2.27602263362211 0.0235113895906361 38.2310828818595 13.8505976053366 2.76024789480051 0.00611191192763496 AMZ1 other 1 1 1 2.27602263362211 2.76024789480051 0.339028191862471 -2.08567817636377 2.11259823268789 -0.987257370612362 0.324269420814146 -14.9315843737736 13.0625967173951 -1.14307933535831 0.253868190090941 GPR171 other 1 1 1 -0.987257370612362 -1.14307933535831 0.00400022202067386 9.62714984825548 11.6463873360813 0.826621128977047 0.409067762787345 -67.5298233405842 23.0760634503654 -2.92640135462597 0.003674457782074 CD164L2 other 1 1 1 0.826621128977047 -2.92640135462597 0.637492067332843 -5.97660156250002 20.7367630102701 -0.288212849784706 0.773370399423388 -44.9603869047621 47.5106338925976 -0.946322606564236 0.344698088075467 FUT1 other 1 1 1 -0.288212849784706 -0.946322606564236 1.134807455822e-24 422.590603435024 37.0251870360345 11.4135980737583 1.60897639527729e-25 325.197869012959 227.479304065335 1.42957123220123 0.153821781690091 DHX36 essential 1.68950134022779e-20 1 2.42633640407816e-21 11.4135980737583 1.42957123220123 0.000256237893110417 12.5133267036378 3.03801918847877 4.1189096998112 4.85863579631923e-05 1.76603957975126 16.6660550147111 0.105966263653419 0.915675931839455 ZIC4 other 1 1 0.519048062120783 4.1189096998112 0.105966263653419 0.00410633556308 45.7274750669583 15.3687230835602 2.97535942435404 0.00314996053319849 -44.8588968227346 41.1385040870664 -1.09043578074191 0.276344205870469 FBXW8 other 1 1 1 2.97535942435404 -1.09043578074191 3.49012261685494e-13 244.370679496759 30.9630341919673 7.89233632536425 4.91137629439022e-14 70.528844305602 178.440744409565 0.395250785009735 0.692924494995254 KLC2 other 4.63976900684696e-09 1 7.0168833117953e-10 7.89233632536425 0.395250785009735 0.0692516839583903 -25.0617764199487 33.9959265057651 -0.737199394042067 0.461541273498894 147.073965960815 75.008636071434 1.96076043591501 0.0507741103631503 SLC22A1 other 1 1 1 -0.737199394042067 1.96076043591501 9.38652681861136e-10 218.923678428861 63.4756765922612 3.44893808434886 0.000638403855119826 -477.29261390323 128.576961514923 -3.7121161386897 0.00024248163794008 CTBP2 other 1.13595747558835e-05 1 1 3.44893808434886 -3.7121161386897 0.00412754825953791 281.611472765743 84.9787167263392 3.31390592391069 0.0010262012343755 -43.3083385104166 435.289581922189 -0.0994931657200983 0.920809404483035 CHST2 other 1 1 1 3.31390592391069 -0.0994931657200983 0.0597637596155372 18.3574068285867 12.0815754257902 1.51945472188997 0.129635464077474 -38.4270806700994 26.4204198895902 -1.45444625144811 0.146802762339676 ZDHHC14 other 1 1 1 1.51945472188997 -1.45444625144811 2.12997419433373e-19 238.537015917612 24.0726731307895 9.90903729808545 2.39008062018458e-20 41.7477887542842 123.492010778732 0.338060644498584 0.735540556702065 ATR ts 3.07461774952074e-15 1 3.55548393058658e-16 9.90903729808545 0.338060644498584 3.42217824573728e-06 1520.12958773062 329.523359011248 4.61311632744898 5.74564358771741e-06 -1259.75760924976 704.79116146884 -1.7874197040501 0.0748159480868876 LRRC75A-AS1 other 0.0339856521584169 1 0.065552047692268 4.61311632744898 -1.7874197040501 4.1249574858449e-05 235.234654419178 56.0445096728893 4.19728276314941 3.5041414380528e-05 -188.015943542063 254.791112288406 -0.737921907296524 0.461102691426645 UBE2C other 0.371576170324909 1 0.378657523795985 4.19728276314941 -0.737921907296524 0.0340095679737261 48.7477990897528 21.1892828042474 2.30058749699548 0.0220638455682642 10.4099704077072 38.6155063621474 0.26958005703925 0.787658738241814 DSG4 other 1 1 1 2.30058749699548 0.26958005703925 3.30244607349382e-11 116.10146867212 16.1112339076387 7.2062431305819 4.1807110246516e-12 99.2133645537794 82.7823632044103 1.19848432339141 0.231618122478748 GK5 other 4.19344602412245e-07 1 5.81662324859778e-08 7.2062431305819 1.19848432339141 1.94237017607777e-10 126.483448515848 19.268042123396 6.56441623418844 2.14190167791999e-10 -119.364546111047 91.1130493357106 -1.31007080743442 0.191123401081178 VCPIP1 other 2.41048138851252e-06 1 2.89199564552758e-06 6.56441623418844 -1.31007080743442 0.156140118460507 2844.10675899081 2178.09989927233 1.30577424843598 0.192570208765282 7145.50451319621 3825.2783755636 1.86796980811715 0.0626829537745579 DES other 1 1 1 1.30577424843598 1.86796980811715 0.0310807953418942 -15.30168850637 18.9454216010969 -0.807672102978384 0.419881206667426 -98.2970102085618 37.1332285531526 -2.64714418968066 0.0085204541742226 PDIK1L other 1 1 1 -0.807672102978384 -2.64714418968066 0.685780796692159 6.99494470598378 8.69305028268571 0.804659409357828 0.42161553588286 -10.0232539155091 42.7996222446564 -0.234190242573006 0.81498752071462 SPSB4 other 1 1 1 0.804659409357828 -0.234190242573006 6.81558879197152e-12 44.2979734623931 9.52369800920671 4.65134167626583 4.87236333507691e-06 -83.9961921487853 23.8944091709918 -3.51530734858085 0.000504109603921427 TRAF6 other 8.80437760146881e-08 1 0.0558226667299762 4.65134167626583 -3.51530734858085 3.27179116230512e-09 40.1099085025655 20.6837496904733 1.93919908637454 0.0534208237740792 -117.927790723624 28.801659497051 -4.09447902596372 5.45528969325597e-05 ZNF654 other 3.87903560202895e-05 0.785943586107387 1 1.93919908637454 -4.09447902596372 1.08302268882567e-08 38.0038297962377 6.76994915630345 5.61360638297448 4.30966217083616e-08 -31.8073188390465 14.155392496435 -2.24701073086155 0.0253227158870876 TVP23C other 0.000125414027366012 1 0.000544267235554899 5.61360638297448 -2.24701073086155 1.40986071098471e-19 220.085786860168 22.5372630771967 9.76541765991325 7.13789047203951e-20 -98.5355132417069 103.580278659504 -0.951296081811286 0.342176557492815 MRPS22 essential 2.04006844879488e-15 1 1.0590488093365e-15 9.76541765991325 -0.951296081811286 1.83200266803805e-26 996.189781223209 84.5964877182086 11.7757818095418 8.73456367308482e-27 -241.409687922564 487.531685340706 -0.495167176167961 0.620826251039121 PACS1 other 2.744339996721e-22 1 1.32040399046023e-22 11.7757818095418 -0.495167176167961 0.0216424714577845 70.0057813394387 42.2256652713118 1.6578964686437 0.0983182862460958 -330.738670621499 188.794892356755 -1.75184119915978 0.080759027194299 WFDC5 other 1 1 1 1.6578964686437 -1.75184119915978 0.0391877720878696 521.573127048242 204.482228491111 2.55070150055076 0.0112203529911327 172.909232722596 459.355115362339 0.376417344533554 0.706858466649558 MARCKSL1 other 1 1 1 2.55070150055076 0.376417344533554 0.00667647545014036 86.6257908161173 29.316401965519 2.95485752030566 0.00336472281416998 -77.1918371866062 87.468251308883 -0.882512637802865 0.378174750913544 SH3BP5L other 1 1 1 2.95485752030566 -0.882512637802865 0.00977151923588054 3.94651060478054 9.35143498680043 0.422021926084184 0.673292398218618 -52.9306642517394 19.3911860249078 -2.72962490194 0.00669153697527474 TMEM51-AS1 other 1 1 1 0.422021926084184 -2.72962490194 0.0863077220306256 35.9770316817811 17.0565611242508 2.10927814931167 0.0357043994106914 39.9908851632741 40.0803596108686 0.997767623632543 0.319153061805456 YPEL2 other 1 1 1 2.10927814931167 0.997767623632543 0.805038925333197 8.70607897726725 48.88902667038 0.178078386300579 0.858774094026291 -62.8060745984434 102.532425523381 -0.612548413614985 0.54061001687426 ABO other 1 1 1 0.178078386300579 -0.612548413614985 8.96346103163542e-27 2185.63803512847 183.354325551511 11.9202970999146 2.48839789647949e-27 1367.00176409851 1205.91146357921 1.13358385369451 0.257823023360799 PSMD2 essential 1.34416061630405e-22 1 3.76419949800453e-23 11.9202970999146 1.13358385369451 0.523748266633253 2.1454713309996 3.76454735881571 0.569914820164343 0.569176702392847 -13.2285999184537 16.5583862296531 -0.798906350835305 0.424998521884637 FAM182B other 1 1 1 0.569914820164343 -0.798906350835305 0.590527685073982 0.894916550214894 3.49640568205243 0.255953293637702 0.798152390401262 -7.73636488810375 8.19065361022992 -0.944535717936017 0.345613043605953 PPM1E other 1 1 1 0.255953293637702 -0.944535717936017 1.3721050353013e-25 140.618185890587 12.351265072229 11.3849217119271 2.03279035730914e-25 172.898516709404 81.2336010917944 2.12841132715547 0.0340715120179423 FAM131A other 2.04992492274014e-21 1 3.06504130075072e-21 11.3849217119271 2.12841132715547 0.0453323031348514 252.52196523705 122.787216756484 2.05658188130333 0.0405472132480605 -283.639437854774 286.957683678634 -0.988436462891244 0.323695168051512 CSRP2 other 1 1 1 2.05658188130333 -0.988436462891244 5.92455702963827e-29 330.360777964884 26.5003430558088 12.4662830692099 2.58793492827873e-29 264.153612025692 175.755313707248 1.50296230852904 0.133841167031862 PARL other 8.93186217788265e-25 1 3.92719125366298e-25 12.4662830692099 1.50296230852904 0.00521023970508809 146.165417289099 47.8633704313238 3.05380536247072 0.00244927614218361 -89.5874441727872 157.907501198152 -0.567341282035534 0.570880117880334 DDIT3 og 1 1 1 3.05380536247072 -0.567341282035534 0.00125548545456847 35.4009461066864 12.206855531663 2.90008725136961 0.00399373063739817 -43.5471070186727 28.3892562041103 -1.53392912817377 0.126054016120965 PCCA other 1 1 1 2.90008725136961 -1.53392912817377 5.69984877464894e-18 631.642141418861 68.8761928790994 9.17068895674306 5.89380867586526e-18 -152.862960688709 227.231542859815 -0.672718931380994 0.501611604832923 DCTN2 essential 8.12456444338459e-14 1 8.65328989790538e-14 9.17068895674306 -0.672718931380994 1.35045524359674e-11 57.3244942555915 13.3212535492666 4.30323573105082 2.25137557671511e-05 -107.424552691445 32.6118880860092 -3.29403045932598 0.00110044489589686 ZNF408 other 1.73087848571795e-07 1 0.246525625650305 4.30323573105082 -3.29403045932598 3.3197399105231e-08 945.161253649556 178.865045016572 5.28421443978608 2.33998880494813e-07 -1090.66856509677 586.041949741942 -1.86107592737523 0.0636503535445762 CTDSP2 other 0.000375728163073004 1 0.00287093226479086 5.28421443978608 -1.86107592737523 6.34610254537449e-12 616.440070136397 134.304200220678 4.58987931221445 6.42203772579533e-06 -1020.312766277 328.791395710569 -3.10322222414594 0.00208834793999058 CKAP5 essential 8.20614520142375e-08 1 0.0730635232063734 4.58987931221445 -3.10322222414594 3.63676409764393e-16 673.223398892759 127.359768931299 5.28599733292474 2.34516247212528e-07 -1221.94536665905 311.790667123531 -3.91912104981295 0.000109123939069635 ARHGAP1 other 5.07983209158905e-12 1 0.00287704532080329 5.28599733292474 -3.91912104981295 2.02449977960844e-13 201.336425593601 59.3715488451563 3.39112638140358 0.000783890834082705 -435.294175471895 96.6860304480635 -4.50214134818287 9.45351419253393e-06 MED16 other 2.70574395544668e-09 0.139240810541832 1 3.39112638140358 -4.50214134818287 1.02645593749027e-23 418.617202350945 60.281801140633 6.94433799969484 2.19289782523857e-11 -675.34112288488 147.576453308302 -4.57621190742419 6.82784831351799e-06 ATG13 other 1.52182357292307e-19 0.100963393011991 3.01479593013798e-07 6.94433799969484 -4.57621190742419 0.65703850729104 13.7223191360081 32.7816335266343 0.418597783568627 0.675800904112345 -41.5684812746988 78.8191491205705 -0.527390637154824 0.598300796717361 CHST1 other 1 1 1 0.418597783568627 -0.527390637154824 0.0429805878593437 137.792487276896 87.1010483791909 1.58198425668795 0.114647205789906 -218.857319345638 181.973092358439 -1.20269055446146 0.229990800339513 GOLGA8A other 1 1 1 1.58198425668795 -1.20269055446146 0.00753246095617295 138.701816346737 110.964116990236 1.24996999128053 0.212262510385237 -528.337356046821 264.433926312275 -1.99799384071051 0.0465992255048332 TP53I11 other 1 1 1 1.24996999128053 -1.99799384071051 0.000817103782317337 -26.5197314661162 14.0419563728691 -1.88860659881808 0.0598516277783142 -110.596411160393 29.6389831573064 -3.73145092641715 0.000225325874601968 CENPS other 1 1 1 -1.88860659881808 -3.73145092641715 7.21693887642937e-13 121.397648414291 15.6361286543716 7.76391977181323 1.12157784664318e-13 0.780638827359844 30.5561616635925 0.0255476730341419 0.979634047316569 DOLK essential 9.53790641908906e-09 1 1.59510801349593e-09 7.76391977181323 0.0255476730341419 0.00324906568475644 2.29208824164627 43.4264319636303 0.0527809478698571 0.957939375386129 -287.236465651371 84.8640417896984 -3.38466633916839 0.000801330011091836 PHYHD1 other 1 1 1 0.0527809478698571 -3.38466633916839 0.105164625116042 43.6800188423977 24.701254523792 1.76833200112672 0.0779581468290929 -129.044249508399 125.19627826922 -1.03073550821458 0.303443275494544 CCNE2 other 1 1 1 1.76833200112672 -1.03073550821458 1.06518252202585e-10 150.282670615765 31.9025261801094 4.71068246343024 3.68589343233008e-06 -159.866762334601 48.4772558694145 -3.29776839607509 0.00108422526284674 PHYKPL other 1.33019993350588e-06 1 0.0425573255696831 4.71068246343024 -3.29776839607509 6.29633092622238e-05 218.624124446736 48.9954195944176 4.46213393530454 1.12877962673812e-05 122.446371019724 265.472754055462 0.461238937515008 0.644943499081659 CST6 other 0.554643791290929 1 0.126141123287985 4.46213393530454 0.461238937515008 1.04440580127987e-06 20.799155460592 3.93228734283835 5.28932746953814 2.36631944860608e-07 1.15427257622946 16.6441490898994 0.0693500502786257 0.944757036005109 ZNF519 other 0.0108002003910351 1 0.00290252743566022 5.28932746953814 0.0693500502786257 1.46425944170087e-24 121.310198279853 18.2425885678679 6.64983468922422 1.48631470133999e-10 -191.494637487887 42.4670348292368 -4.50925378373842 9.5021637099777e-06 LSM1 other 2.17837877141839e-20 0.139947867120552 2.01306463149488e-06 6.64983468922422 -4.50925378373842 3.31102671725898e-12 691.571496169285 91.478896577164 7.55990203255166 4.38104467809602e-13 245.977347426823 489.486151541141 0.50252156603893 0.615649596797328 BANF1 essential 4.30897016984083e-08 1 6.17508247377634e-09 7.55990203255166 0.50252156603893 3.62840282824407e-16 98.154889303631 35.8184954169189 2.74034093730435 0.00648320303569203 -440.868802758422 72.1104580758259 -6.1137983937758 2.83925987070251e-09 TMEM9B other 5.06851591077414e-12 4.32589633900235e-05 1 2.74034093730435 -6.1137983937758 0.172341951502447 -44.8561032823657 31.300527464087 -1.43307819121681 0.152814794989551 -110.794430508707 63.0148013527153 -1.75822867215836 0.0796675534886817 NRIP3 other 1 1 1 -1.43307819121681 -1.75822867215836 1.04983120988085e-46 412.290307171076 23.8231309617221 17.3063023426067 2.89185160814379e-47 97.5452808593761 100.070746855983 0.974763194280532 0.330447673662339 PTPN2 other 1.60718659920659e-42 1 4.42973829335465e-43 17.3063023426067 0.974763194280532 0.702976546515426 -57.8894354649797 89.2778327127145 -0.648418915491162 0.517181978298731 -140.993435664524 180.530987230092 -0.780992990886509 0.435387623983485 SCUBE2 other 1 1 1 -0.648418915491162 -0.780992990886509 1.07642912027363e-34 204.671433309905 14.7471492163067 13.8787117637346 1.51231104337353e-34 -81.0352480316817 78.9091865576228 -1.02694314270375 0.305230202537841 EIF1AD essential 1.63671047737606e-30 1 2.30551818562294e-30 13.8787117637346 -1.02694314270375 3.67813739362116e-25 593.081412475932 89.8090725593093 6.60380288510679 1.70377268405424e-10 -557.70160143792 144.981221060429 -3.84671612888036 0.000144900532690723 SMAD2 ts 5.48667755006469e-21 1 2.30435255518336e-06 6.60380288510679 -3.84671612888036 7.62807965375324e-10 305.225166187652 77.9457334173395 3.91586752482533 0.000110125650658734 -447.772295140045 155.496890374889 -2.87962218447266 0.00424985737476719 EIF3F essential 9.26887958727557e-06 1 1 3.91586752482533 -2.87962218447266 0.0820753956215173 8.7244016722151 9.11631668140487 0.957009500340288 0.339356840232404 -24.5477453386175 18.6417996578788 -1.3168119918209 0.188937718605069 ZNF25 other 1 1 1 0.957009500340288 -1.3168119918209 4.74670409119627e-07 114.563286208048 21.6124125633306 5.30080970240341 2.1526349237341e-07 12.1492651469561 32.9088701049707 0.369179042252229 0.712238434629747 ARL10 other 0.00502628496216773 1 0.00264515779428446 5.30080970240341 0.369179042252229 0.00184872792186516 1374.68281938109 531.580346739592 2.58603017928071 0.0101503677409397 -1166.16751064037 809.42877293069 -1.440729004997 0.150638980668206 CLTB other 1 1 1 2.58603017928071 -1.440729004997 0.465054527771056 8.65768910890101 7.56991915693604 1.14369637633029 0.253604414882279 9.69002026922709 10.8012400879855 0.897121088902145 0.370328737223779 PCSK1 other 1 1 1 1.14369637633029 0.897121088902145 0.874468671770218 27.6750554126724 55.9151397711584 0.494947442247966 0.62097901581073 44.4083095627776 103.341696425004 0.429723055640036 0.667688139918739 LPL other 1 1 1 0.494947442247966 0.429723055640036 1.31361188094205e-05 3.99452406390182 1.77708117707547 2.24780055938444 0.0252717195139892 -7.54536960095544 2.52516450840958 -2.98807051018934 0.00302531579320012 RFESD other 0.124096914392596 1 1 2.24780055938444 -2.98807051018934 5.6214324129421e-06 153.527799219002 32.871111362104 4.67059958903606 4.42728900886522e-06 -121.028302415247 128.844921397881 -0.939333123123292 0.348268213829568 CCDC14 other 0.0548651803503149 1 0.0508562688448348 4.67059958903606 -0.939333123123292 1.0482081539591e-05 -43.7624488789196 11.3682647789628 -3.84952758664655 0.000143928033654957 133.62241065516 61.3594679180517 2.1776983273978 0.0301870815496209 TBC1D10C other 0.0998523087461439 1 1 -3.84952758664655 2.1776983273978 1.51277686891239e-25 680.274266414373 58.5443102773083 11.6198186158843 3.14851760908887e-26 29.8975885049724 313.021436017538 0.095512910826009 0.923967976078801 SART1 essential 2.25978608678132e-21 1 4.75520614500692e-22 11.6198186158843 0.095512910826009 1.93664297841055e-10 99.3084923046624 25.7816600249437 3.85190450143945 0.000141750321094729 -183.299945837201 52.1128558558317 -3.5173652034019 0.000499307261209628 PPP2R2D other 2.40356760050533e-06 1 1 3.85190450143945 -3.5173652034019 0.00010993065259021 42.9050181349299 28.9433729654631 1.48237795871706 0.139230042584805 -128.265867266702 40.9125445690169 -3.13512319064696 0.00187813228906406 MCTP1 other 0.942545415308458 1 1 1.48237795871706 -3.13512319064696 6.30169107389185e-12 391.506139449486 54.1258545398594 7.23325558141854 3.76041855567658e-12 -142.710200666538 292.140770799204 -0.4884980630267 0.625544713163743 POLD4 other 8.14997706586433e-08 1 5.23600679692407e-08 7.23325558141854 -0.4884980630267 0.298051718466969 -13.7454812218166 9.08027142173586 -1.51377426768471 0.13107946677076 -1.80257810549831 21.2756926332925 -0.0847247672058211 0.932533687175749 LRRC25 other 1 1 1 -1.51377426768471 -0.0847247672058211 3.65074609524505e-07 56.3466994042749 10.8545734684658 5.1910560620342 3.80421510030485e-07 -57.1853350515549 58.5868525630196 -0.976077951790343 0.32979183215647 CLCF1 other 0.00390228250120743 1 0.00462326261140049 5.1910560620342 -0.976077951790343 5.51879281234773e-08 3.75377184089691 1.28708601521093 2.91648871678692 0.00379330522103555 -14.9449547438303 4.46538637948937 -3.3468447013849 0.000916019565568357 LIPT2 other 0.000617001036420477 1 1 2.91648871678692 -3.3468447013849 0.0523076712282681 -81.7965293100361 39.9909985134172 -2.04537351780784 0.0416458867514472 -291.279827053381 138.743843032688 -2.09940722908155 0.0365739063860648 KCNE3 other 1 1 1 -2.04537351780784 -2.09940722908155 0.259932785201025 14.619670438411 12.5670062701872 1.16333756219199 0.245595966677139 -32.3838415252521 34.0892971724643 -0.949970935493802 0.342874259532325 ALG10B other 1 1 1 1.16333756219199 -0.949970935493802 4.0661322526492e-10 754.715260442671 115.092490064072 6.55746747700496 2.222493097283e-10 -518.102762522883 621.305807482405 -0.833893319977627 0.404969015495364 DRAP1 other 4.99199056657743e-06 1 2.99880993616395e-06 6.55746747700496 -0.833893319977627 0.949161512094164 2.4811969827759 7.77346382380662 0.319188078701429 0.749794790502491 2.5287517710348 27.3040651165402 0.0926144792081871 0.926268527870268 UCP3 other 1 1 1 0.319188078701429 0.0926144792081871 0.330732000644935 -88.7128165471187 60.617678724527 -1.46348092526387 0.144329805218503 -80.3992962878711 212.917829763245 -0.377607156607183 0.705975940888417 UCP2 other 1 1 1 -1.46348092526387 -0.377607156607183 2.84470218687208e-16 209.458333048373 24.2191970692085 8.64844249170721 2.64868222785536e-16 -136.307625320011 130.742916269194 -1.04256222218081 0.297945522208135 C11orf68 other 3.97973835943404e-12 1 3.85224343219283e-12 8.64844249170721 -1.04256222218081 4.15759989968177e-35 114.016760884559 9.93893436457707 11.4717289301076 1.05727877922055e-25 -98.173615049963 34.9102172764138 -2.81217427759441 0.00522849159857674 PAAF1 other 6.32537248737584e-31 1 1.59543367784382e-21 11.4717289301076 -2.81217427759441 3.15942446804728e-18 116.405849944134 15.0186278613275 7.75076465166805 1.27912530854695e-13 -91.6537658681132 52.6326817945628 -1.74138506234317 0.0825954647754865 MRPL48 other 4.51323785260553e-14 1 1.81738123838351e-09 7.75076465166805 -1.74138506234317 3.55489531937613e-42 751.996996660625 65.7583821448629 11.4357587904764 1.53943761755227e-25 -1256.28910919373 231.134347842892 -5.43531985149892 1.10214146078903e-07 RAB6A other 5.43507945379417e-38 0.00166577660383654 2.32162587103058e-21 11.4357587904764 -5.43531985149892 1.56812691872418e-13 87.459784463922 16.9684126418135 5.1542702496758 4.53555386926893e-07 -218.930089710502 62.4948998381285 -3.50316730289295 0.000527185410310434 P2RY2 other 2.10034919493917e-09 1 0.00549255573568467 5.1542702496758 -3.50316730289295 8.1541415821618e-11 801.570960910235 122.643845908374 6.53576178220209 2.52587344657469e-10 -1130.14281089781 662.070424164337 -1.70698277652906 0.0888044798367479 FOSL1 other 1.0229370614822e-06 1 3.40487740598268e-06 6.53576178220209 -1.70698277652906 0.000474756561648214 36.3180285427506 11.169640671971 3.2514947982066 0.00127034010372575 -49.9368533751745 35.7407539798718 -1.39719641626189 0.16332255351003 ERCC4 other 1 1 1 3.2514947982066 -1.39719641626189 4.21195182110504e-07 58.6526716059076 10.9775501978261 5.34296546578512 1.73983008884704e-07 -20.3675073189082 45.1283742389712 -0.451323755007322 0.652061930135259 SUGCT other 0.0044751988099241 1 0.00214521049954841 5.34296546578512 -0.451323755007322 0.00157957963935549 198.449663404437 56.1908399417785 3.53170843521931 0.000474166723685199 -91.1670279968191 303.335996672813 -0.300548002864145 0.76395619904838 CCDC85B other 1 1 1 3.53170843521931 -0.300548002864145 5.21233831739371e-06 58.2041382293264 13.2410559388272 4.39573237196683 1.50828213164758e-05 -118.347957872603 61.1679267582359 -1.93480413910986 0.0539037737187323 TMEM70 other 0.0509870934207453 1 0.167162908650502 4.39573237196683 -1.93480413910986 0.015421897152108 5.3291714990599 3.47649250612688 1.5329161474296 0.126287634248556 -15.0999639785784 6.66653357842987 -2.26503981431003 0.0241806785299163 LINC00476 other 1 1 1 1.5329161474296 -2.26503981431003 5.36624863390471e-12 405.23430774782 57.8542627739882 7.00439843699844 1.56418384313366e-11 -397.919204990233 308.421219341946 -1.29018102528497 0.197955595520461 RPS6KB2 other 6.95251173008694e-08 1 2.15607100937544e-07 7.00439843699844 -1.29018102528497 0.469377223611328 -9.89471926079088 42.4737139708303 -0.232961008956888 0.815940620462932 -169.425347458407 137.815692738833 -1.22936179539057 0.219839353742987 RMI2 other 1 1 1 -0.232961008956888 -1.22936179539057 0.000768922136475735 227.807473233957 83.8256844622523 2.71763332080565 0.00693425914660666 -400.255960079481 156.933363825251 -2.55048353213899 0.0112242565474504 TOM1L2 other 1 1 1 2.71763332080565 -2.55048353213899 7.29991601297611e-06 21.1578039562354 6.80527222302858 3.1090312426649 0.00204672127853163 -22.1473475751353 11.8170063978855 -1.87419273794235 0.0618205686537849 ZNF77 other 0.0705463883494012 1 1 3.1090312426649 -1.87419273794235 0.0159588040974444 13.4166560039581 4.78752734961608 2.80241866504093 0.00538323658002383 22.7798221744533 18.8339221193012 1.20951026717416 0.22736528250683 GPR156 other 1 1 1 2.80241866504093 1.20951026717416 3.74649179461958e-06 61.5939400371238 20.6984290567787 2.97577849353509 0.00314506600436866 -131.530679262889 40.6896567231327 -3.23253351970678 0.00135483514351345 KDF1 other 0.0370940152585284 1 1 2.97577849353509 -3.23253351970678 0.487565949696005 17.1791285692657 16.0209771571 1.07228968625378 0.284426675453235 27.0935140965731 35.3380057417205 0.766696182421697 0.443847525236146 B3GNTL1 other 1 1 1 1.07228968625378 0.766696182421697 4.24886351716454e-09 485.87484175904 78.5385911725388 6.1864471275228 1.87920948002169e-09 -126.48113106782 205.054420178205 -0.616817384174893 0.537793774429529 MLXIP other 5.01833270012304e-05 1 2.48262364405665e-05 6.1864471275228 -0.616817384174893 0.881483052277621 -8.51868262008389 21.6744537956703 -0.393028710222242 0.694560795156735 -13.3741714060255 30.1668172342908 -0.443340485744813 0.657819998175158 NR2F1 other 1 1 1 -0.393028710222242 -0.443340485744813 0.00267833100152212 154.004883969988 156.810492252201 0.982108287258602 0.326800208813831 -1038.71199091688 355.703372217155 -2.92016346216349 0.00375084955647004 AURKAIP1 essential 1 1 1 0.982108287258602 -2.92016346216349 1.04596787756219e-05 32.4782649424361 6.66610867588926 4.87214753337388 1.73960159770643e-06 5.81595544373595 13.3350580873169 0.436140240683884 0.663029071030477 TTLL11 other 0.0996702790529014 1 0.0204594543906253 4.87214753337388 0.436140240683884 7.09919294746957e-27 369.801224496485 33.5203218653747 11.0321501679397 4.19806235563997e-24 -216.264001560602 99.3479484275283 -2.17683409656276 0.0302448020346543 TOMM5 other 1.06480795019096e-22 1 6.31151015828023e-20 11.0321501679397 -2.17683409656276 8.73606400907363e-34 93.0238709877505 6.65783981521635 13.9720800694463 7.43215150080753e-35 25.5884546441309 41.7053570864606 0.613553184332717 0.539953417841567 SLC35E3 other 1.32674604105801e-29 1 1.13332878235814e-30 13.9720800694463 0.613553184332717 0.130460293233876 -52.913707355168 26.3004853725301 -2.01189090641021 0.045069268592093 -28.0866091050736 79.3347133455017 -0.354026729544692 0.723552005992534 PRIMA1 other 1 1 1 -2.01189090641021 -0.354026729544692 0.00483838841045783 2.67492555665933 1.90673142761616 1.40288533451383 0.16162051330837 -10.0178734589824 3.63740842769291 -2.75412389291031 0.00622145888913418 ZNF169 other 1 1 1 1.40288533451383 -2.75412389291031 4.11790682631005e-19 561.477184785739 57.8337452338965 9.70847007253225 1.06488025566664e-19 42.487875626805 232.518192728654 0.1827292528305 0.855126173502765 RUVBL1 essential 5.93349194603015e-15 1 1.57836551494909e-15 9.70847007253225 0.1827292528305 0.0246485076683142 6512.67172758198 7617.31285156805 0.854982833774685 0.393200309453245 -34321.2383841701 14974.3656503006 -2.29199948670154 0.0225546383621413 SFN other 1 1 1 0.854982833774685 -2.29199948670154 8.96396981291608e-08 10.8506105624538 13.9465974051855 0.778011313241134 0.437137192303594 -106.319229778576 27.0228713470458 -3.93441645830872 0.000102321921727666 MSRA other 0.000992401097987939 1 1 0.778011313241134 -3.93441645830872 1.97334937025503e-27 644.869613217758 52.7622935688481 12.2221679460595 1.88215513327546e-28 -21.048631980487 100.7125578217 -0.208997094659747 0.834583483777305 CTDNEP1 other 2.96515476374521e-23 1 2.85221788896562e-24 12.2221679460595 -0.208997094659747 0.0641043493712111 145.387494941892 63.342336732086 2.29526573288297 0.0223665486522544 -52.1978018806259 152.65809785838 -0.341926190702635 0.732631586144857 ETV4 other 1 1 1 2.29526573288297 -0.341926190702635 0.00465554909268932 71.3156433159548 21.5835206539376 3.30417101358968 0.00106056803838593 13.2724525444804 42.0304483465936 0.315781845461949 0.752373953659738 SWI5 other 1 1 1 3.30417101358968 0.315781845461949 0.0268600569016813 -3.07420310447136 2.42310694029414 -1.26870302476133 0.205477830590534 -10.7514844947208 3.99054612727524 -2.69423887152557 0.00743077826100961 GAPT other 1 1 1 -1.26870302476133 -2.69423887152557 3.73668355912829e-07 566.660556065418 144.256659284267 3.92814140350204 0.00010503139507955 -976.447750774916 332.694679536573 -2.93496653488736 0.0035786994330348 BAIAP2 other 0.00399003070443718 1 1 3.92814140350204 -2.93496653488736 0.0181703948811385 23.3772516485536 15.9099032437032 1.46935221983866 0.14272586653427 -106.432558322618 50.0380795332239 -2.12703123931745 0.0341869368754487 CREG2 other 1 1 1 1.46935221983866 -2.12703123931745 0.125131265074214 10.2019478114793 5.39121983218864 1.89232643613749 0.0593790856417798 20.0434422364254 19.6098499644415 1.02211094285628 0.307525354846346 HOXD8 other 1 1 1 1.89232643613749 1.02211094285628 3.1356130556886e-17 163.226345914933 19.6483370863628 8.30738729682234 2.9697290136776e-15 -214.648826545594 73.7868142092907 -2.9090404409758 0.00388407205598937 ZDHHC21 other 4.4315619316047e-13 1 4.28710080414499e-11 8.30738729682234 -2.9090404409758 0.304623843621937 -13.5826359432918 15.9748867260958 -0.850249280397328 0.395824213103521 -40.2365661660745 26.4664274457952 -1.52028702205771 0.129429383046062 TSPEAR other 1 1 1 -0.850249280397328 -1.52028702205771 6.48113325374315e-07 108.96616402015 21.6100374473014 5.04238663564912 7.71347821780563e-07 -180.907762629609 109.528698595236 -1.65169279786803 0.0995780992175219 PLEKHF2 other 0.00679824492222288 1 0.00923766151364402 5.04238663564912 -1.65169279786803 0.330533359351881 357.596713388111 246.948472221993 1.44806205995335 0.148581814167173 -188.262446283491 1341.75119405997 -0.140310995896216 0.888502829097114 A2M other 1 1 1 1.44806205995335 -0.140310995896216 0.0600475150931557 153.034549101898 79.6677833683184 1.92090883706896 0.0556342764110265 -240.404718050803 191.28966689785 -1.25675747127094 0.209760926962616 ARL4D other 1 1 1 1.92090883706896 -1.25675747127094 0.408132496154048 6.53205809841124 11.4036546025011 0.572803923487703 0.567179711829793 -14.4218524776105 21.0974757002656 -0.683581897782631 0.494733884807749 DOK7 other 1 1 1 0.572803923487703 -0.683581897782631 0.0124072350285499 86.0830333226085 37.3516622714143 2.30466405208662 0.0218354351298969 -41.6194734407218 61.9518206103244 -0.671803879703672 0.502200958743366 LRRN1 other 1 1 1 2.30466405208662 -0.671803879703672 1.13252117303264e-14 260.155230084361 32.8283597801812 7.92470997108479 3.86025363619756e-14 -113.67050238623 81.2900571078556 -1.3983321753042 0.162984704173762 UBE2O other 1.54928896470865e-10 1 5.51977667439888e-10 7.92470997108479 -1.3983321753042 0.681230804311233 3.52217242648703 32.5831810305346 0.108097868749718 0.913987541085391 -90.0352505466065 112.068959841619 -0.803391507102846 0.422360106760434 ORAI3 other 1 1 1 0.108097868749718 -0.803391507102846 1.53215249643901e-06 129.301988241634 48.0217746023005 2.69256997086151 0.00746482963022562 -240.096391972159 87.4962093415438 -2.74407764380895 0.00641157305188657 DENND2C other 0.0156432769886422 1 1 2.69256997086151 -2.74407764380895 5.90973921855838e-16 1460.49627557033 175.814919416592 8.30700989663848 3.06456444524827e-15 -1097.76455675902 751.096169721999 -1.46154993329993 0.144874226520573 TUBB6 other 8.23581257498295e-12 1 4.42369877671588e-11 8.30700989663848 -1.46154993329993 1.04313493757233e-06 48.2826786318995 19.5062747116694 2.4752383192376 0.0138338671371759 -91.6748194540558 27.1372322303998 -3.3781934235489 0.000820053168325783 LYSMD3 other 0.010788101524373 1 1 2.4752383192376 -3.3781934235489 1.05961693643161e-15 16.8212718395396 10.0860143733509 1.66778186277272 0.0963403301714599 -91.0789005178509 14.242875363248 -6.39469897720716 5.71614775876296e-10 AMIGO3 other 1.4718079247035e-11 8.7319873162863e-06 1 1.66778186277272 -6.39469897720716 8.36971282504411e-05 110.633485372468 37.4717759019945 2.95244841509045 0.00338959486898252 -195.084153352734 84.999650596517 -2.29511712087824 0.0223834438430978 B3GALT6 other 0.72674216459858 1 1 2.95244841509045 -2.29511712087824 0.0710916707367573 8.85081139541862 4.62391194439423 1.91413926170217 0.0564968830385537 -9.28156400027902 11.4214306223691 -0.812644607068829 0.417027897826958 ZNF613 other 1 1 1 1.91413926170217 -0.812644607068829 0.471018614115384 -139.415961221602 211.042722997389 -0.6606053942136 0.509343662798304 -885.810216562382 749.333775160664 -1.18213037490864 0.23803715249865 NUPR1 other 1 1 1 -0.6606053942136 -1.18213037490864 0.428931584301165 -50.9964941941558 41.2437377782612 -1.23646635686436 0.217192009475535 -2.37118469979291 59.7909383662147 -0.0396579275151963 0.968390574616363 JAKMIP2 other 1 1 1 -1.23646635686436 -0.0396579275151963 2.38241655755603e-05 15.9459871317304 8.077629818431 1.97409233774812 0.0492336601715079 -35.0335651045118 11.2376411946474 -3.11751945961744 0.0019898682159552 MBLAC2 other 0.21963498244109 1 1 1.97409233774812 -3.11751945961744 1.69323216821382e-08 133.23316615354 23.8118288547127 5.59525129155174 4.756815634506e-08 -91.971975189375 50.1673741443314 -1.8333025548591 0.0676922060478264 TPRN other 0.000194552376127768 1 0.000599977155980241 5.59525129155174 -1.8333025548591 0.684457511019558 -3.36105734378621 9.78072297252509 -0.343640991900876 0.731341967099054 -16.5655175777524 19.1856238025389 -0.863433878837975 0.388545643255927 ZNF683 other 1 1 1 -0.343640991900876 -0.863433878837975 5.34939894760183e-21 443.28101004119 73.5362368869605 6.02806220180398 4.56837924859378e-09 -646.754021051497 107.975582238471 -5.98981739800298 5.64672986699572e-09 SLC35A4 other 7.8165417422358e-17 8.59262883860739e-05 5.96767381243805e-05 6.02806220180398 -5.98981739800298 0.000276790262972689 162.030491678312 114.168377350418 1.41922391680308 0.156807067703502 -744.953914770408 223.949859754175 -3.32643170925906 0.00098199909425398 CRYBG2 other 1 1 1 1.41922391680308 -3.32643170925906 6.57848173315859e-20 163.219462476383 42.9442689920435 3.80072746159968 0.000172795367050206 -356.261609366271 60.6433669612411 -5.8747003541866 1.06496138456431e-08 IP6K1 other 9.53879851307996e-16 0.000161852831226083 1 3.80072746159968 -5.8747003541866 5.99985714862069e-11 311.55978746648 52.3306398062944 5.95367816292215 6.93144736967117e-09 -344.362392220947 110.251539366958 -3.12342479931081 0.00195206882574851 SSNA1 other 7.56341992155124e-07 1 9.00464327793982e-05 5.95367816292215 -3.12342479931081 1.0020448530975e-06 65.7948728391978 22.5367307376377 2.91945063395182 0.00375519096452525 -195.988668695343 62.1773722667112 -3.15208992516836 0.00177449276037098 CSTF3 essential 0.0103761744538246 1 1 2.91945063395182 -3.15208992516836 1.20534825958495e-50 1030.558357714 55.2381479416808 18.6566421235202 8.54167098910485e-52 526.364019601393 249.684882535422 2.10811329166763 0.0358673238962788 YES1 other 1.84743727746585e-46 1 1.30995066288912e-47 18.6566421235202 2.10811329166763 0.0328348330438416 59.9402776444996 26.0119813634199 2.30433340725026 0.0218480542896292 -41.5374262084751 59.9745606870266 -0.692584084529364 0.48907604641304 CHMP6 essential 1 1 1 2.30433340725026 -0.692584084529364 4.40572391637207e-05 29.2357630925984 7.22450790883603 4.04674802235889 6.53083655172236e-05 -4.39268766485412 13.4011371890742 -0.327784694901522 0.743290838183318 DLEU1 other 0.395589950451048 1 0.68991757332395 4.04674802235889 -0.327784694901522 3.00988482915103e-06 9.38163372807218 1.83029350169326 5.12575372168068 5.13819626732004e-07 5.54529578502587 8.02257349347078 0.691211590587352 0.489933706492971 UFSP1 other 0.0300296209404398 1 0.00620642727129588 5.12575372168068 0.691211590587352 3.06558937287403e-19 208.193639054517 21.3079096091198 9.77072096107494 6.85626902773092e-20 18.4062719474089 83.8243796425423 0.219581367925417 0.826338084295936 TMEM39A other 4.42088643462165e-15 1 1.01747032371527e-15 9.77072096107494 0.219581367925417 3.21763178229381e-22 106.53630672198 12.5729573586077 8.47344850406602 8.82036192926687e-16 -109.02338554364 34.6879704638821 -3.14297389226499 0.00182896300310094 TCP11L1 other 4.73667574671471e-18 1 1.27798223993148e-11 8.47344850406602 -3.14297389226499 0.745648105531866 179.416164149559 356.148220786916 0.503768245010844 0.614774151727932 -524.73444986874 1191.16589075614 -0.440521722407315 0.659859525754122 GPX2 other 1 1 1 0.503768245010844 -0.440521722407315 0.254978606581773 22.754164487673 22.1919540818325 1.02533397481661 0.305987402003732 -51.5883508869723 49.7063120129588 -1.03786317668313 0.300124761210175 CCDC57 other 1 1 1 1.02533397481661 -1.03786317668313 0.969677058628136 -1.23662543483492 5.86806727460109 -0.210738114777149 0.833228322762383 1.24524268182773 15.8717384480941 0.0784566029676014 0.937514822423471 FOXG1 other 1 1 1 -0.210738114777149 0.0784566029676014 3.15095337228577e-09 599.861390456576 98.0715086270883 6.11657145744048 2.80419388755546e-09 -220.007143631757 242.790364971303 -0.906160932942133 0.365536758176926 SPHK1 other 3.73797598554261e-05 1 3.68779538152419e-05 6.11657145744048 -0.906160932942133 0.00202050418678239 324.493845136604 114.77064733737 2.82732434350352 0.00499136224432432 -166.356816774992 231.987629787463 -0.717093480059264 0.473842790006975 BNIP3 other 1 1 1 2.82732434350352 -0.717093480059264 1.27280848319745e-06 38.2677251815548 8.81749131668733 4.33997877708506 1.91352627878364e-05 -39.9841203996552 20.6223533124099 -1.93887282377196 0.0533957736386446 MYPOP other 0.0130805906537797 1 0.21058356698014 4.33997877708506 -1.93887282377196 0.153442399493747 8.02930191985194 5.62628401726089 1.42710568738066 0.154549437873346 -24.4969989614325 24.0540888098892 -1.01841309205448 0.309270735122019 CIDEA other 1 1 1 1.42710568738066 -1.01841309205448 0.0407772637235826 13.9119083453361 13.5414516996153 1.02735723273535 0.305043030697651 -71.3134854480534 32.9230017727204 -2.1660687546159 0.0310581595068586 ATAD5 other 1 1 1 1.02735723273535 -2.1660687546159 1.02635477924529e-16 51.6635031710175 18.6689599817713 2.76734768414859 0.00603927054911537 -262.086464309132 43.7124391343088 -5.99569526431269 6.42343979131407e-09 SMIM19 other 1.44182319388378e-12 9.77133661054697e-05 1 2.76734768414859 -5.99569526431269 3.15073251195142e-17 12.7671470742561 1.38181205499456 9.2394237176534 3.60103461394085e-18 5.1765427331403 5.81933707389596 0.889541655244707 0.374382367333487 ZNF404 other 4.45261518588975e-13 1 5.2967618136456e-14 9.2394237176534 0.889541655244707 1.2250051212118e-07 79.6307249210246 41.2252447595743 1.93160102227242 0.0542970952005504 -188.263371809061 62.7094846607617 -3.00215147401555 0.00289320570095766 RTTN essential 0.00134468812155419 1 1 1.93160102227242 -3.00215147401555 1.79099388989398e-21 226.281780713079 23.9419040769712 9.4512859121648 7.58817524287987e-19 -174.854986502225 50.4414199717966 -3.46649611767457 0.000599785826146321 ANAPC2 essential 2.62470154563963e-17 1 1.12031819285878e-14 9.4512859121648 -3.46649611767457 0.00023291268476955 29.5244956772333 18.8325221381009 1.56773986302668 0.117936357016571 -143.399993868417 42.3286707323745 -3.38777456006288 0.000793191453347122 ZBTB8OS other 1 1 1 1.56773986302668 -3.38777456006288 0.198232307440495 16.1133725778136 44.1444509107347 0.365014678977358 0.715342327912219 147.388703327693 84.8121672484054 1.73782498560622 0.0832066846999745 SLC35G1 other 1 1 1 0.365014678977358 1.73782498560622 0.540708539578604 20.0574932571058 18.0929702683715 1.10857935206849 0.268449403108523 17.3676019018085 47.0923459146739 0.368798826316206 0.712523093817744 ZNF135 other 1 1 1 1.10857935206849 0.368798826316206 0.00793748756661215 257.559664813406 114.585229542087 2.24775624085829 0.0252810861937864 -696.192826916419 463.702989203252 -1.50137662065245 0.134256718673956 COX8A other 1 1 1 2.24775624085829 -1.50137662065245 0.0758107082843918 12.6061312927299 6.49177167669303 1.94186301067685 0.0530310478901782 -6.80831819542595 12.7212384961355 -0.535193031519234 0.592888100965264 ZSCAN2 other 1 1 1 1.94186301067685 -0.535193031519234 0.00283800891399268 107.684077043889 32.1799993618278 3.34630451147941 0.000916467440025806 117.40447035799 84.0179459799355 1.39737372758467 0.163269300394996 B3GNT4 other 1 1 1 3.34630451147941 1.39737372758467 0.00661146971975525 30.3652413646848 9.93052536709759 3.05776786647086 0.00241803952996717 -12.7232104198147 19.8735853209489 -0.640207099742744 0.522496093893771 CDC26 essential 1 1 1 3.05776786647086 -0.640207099742744 0.52414612991011 9.67282124000711 73.57988058259 0.131460137790654 0.895494188631991 -192.647120835883 196.967213481388 -0.97806694541113 0.328782356992034 HSD11B2 other 1 1 1 0.131460137790654 -0.97806694541113 1.62140438588611e-05 51.9064747819062 17.2848373219189 3.00300626584918 0.00288737896287933 -138.023403893444 42.0347840093949 -3.28355211394913 0.00114037495473669 CRLF3 other 0.151958019045246 1 1 3.00300626584918 -3.28355211394913 1.86261612356533e-05 280.240323147235 59.42241977329 4.71607053728904 3.59585405278366e-06 -85.2630389961377 202.104532396293 -0.421875937096508 0.673398849218388 RNPEP other 0.173465439587639 1 0.0415429018718096 4.71607053728904 -0.421875937096508 4.69403786744868e-17 67.3835995362405 8.08131927526407 8.33819296590514 2.28847815888856e-15 -41.1309551540307 25.3445225745756 -1.6228735433072 0.10560422934555 EID2 other 6.62047100824962e-13 1 3.30685093959397e-11 8.33819296590514 -1.6228735433072 0.982706646848193 1.34597026961181 8.43882994691228 0.15949726183359 0.873385893174071 -1.11436705235334 18.7700182481581 -0.0593695241858752 0.952697848159886 DMRTA1 other 1 1 1 0.15949726183359 -0.0593695241858752 0.00115998789483907 4.26707627595056 1.667956700755 2.5582656156596 0.0109811752480174 -10.1852434838394 5.23094542455673 -1.94711331455011 0.0523984505937085 EID2B other 1 1 1 2.5582656156596 -1.94711331455011 0.0293215931540284 25.4373334131953 11.3561869756106 2.23995373339894 0.025782345792977 -86.5784258450274 63.6657147442298 -1.35989089563899 0.1748247767998 RIMS2 other 1 1 1 2.23995373339894 -1.35989089563899 8.62081245195408e-08 288.329910645717 50.5288552397837 5.7062426860346 2.65195643929837e-08 -173.940314230731 208.551331077106 -0.834040777070955 0.404886044437181 KCMF1 essential 0.000955272227801032 1 0.000337885769931006 5.7062426860346 -0.834040777070955 1.45077984312368e-06 49.3713048874446 11.254421539463 4.38683629490213 1.56758605915942e-05 -66.8076309557859 38.8313882563562 -1.72045435292544 0.086325739921791 DNAJC30 other 0.0148443793548415 1 0.173563128470131 4.38683629490213 -1.72045435292544 0.204330553025767 44.5283951033624 30.1816046833252 1.47534882822064 0.141102009964324 -60.8111622047396 86.2315119461111 -0.705208117454121 0.481193722995993 SPRYD4 other 1 1 1 1.47534882822064 -0.705208117454121 0.00631153085195531 18.8605771217152 5.87875707368633 3.20825931150246 0.00147192546177105 17.7386927874774 20.2836100987209 0.874533315378409 0.382489962389135 VPS37D other 1 1 1 3.20825931150246 0.874533315378409 0.425938870205747 -6.19509067065668 10.5484043718354 -0.58730121184942 0.557430315080249 29.8605718885339 30.1110997776192 0.991679882470733 0.322129617267942 CLEC14A other 1 1 1 -0.58730121184942 0.991679882470733 0.931638498369786 1.9239815418877 11.8310876435369 0.162620851087916 0.870920256274333 12.9469881465947 34.8984879325561 0.370989945799822 0.710892044424399 SYNE3 other 1 1 1 0.162620851087916 0.370989945799822 1.5214196487778e-08 150.909041679832 24.4797183439109 6.16465596375495 2.13937771650288e-09 -40.5731145816412 84.6462280535619 -0.479325724425282 0.632036384908848 CLK2 other 0.000175039330591886 1 2.8226949591539e-05 6.16465596375495 -0.479325724425282 0.00235626519733822 249.454418168901 111.673677973636 2.2337799085277 0.0261925680358682 -382.884254921944 233.310676439091 -1.64109187271548 0.101766977554519 LPCAT4 other 1 1 1 2.2337799085277 -1.64109187271548 0.000509971038383417 317.876625960367 94.7218759811658 3.35589453510794 0.000886630697601262 -188.534777575209 197.196413886143 -0.956076096211692 0.339757762652322 SLCO3A1 other 1 1 1 3.35589453510794 -0.956076096211692 0.00802409687660319 11.2189034808792 9.40543768991759 1.1928103561736 0.23383288974853 -58.4849440285642 23.4019929279834 -2.49914373568713 0.0129533185240064 ZNF575 other 1 1 1 1.1928103561736 -2.49914373568713 4.46110251236396e-07 26.0087426343761 6.25913064059833 4.15532829202777 4.18941708404337e-05 -43.7842532713895 18.8650469935004 -2.32091938527768 0.0209293165759144 WDR25 other 0.00473322976561816 1 0.449985288997099 4.15532829202777 -2.32091938527768 0.319997681455998 15.9376174592629 17.9230181894419 0.889226205698514 0.374553688425558 -58.2585427604912 63.6379340231217 -0.915468794749434 0.360639248445223 SGF29 other 1 1 1 0.889226205698514 -0.915468794749434 0.997927293540877 -1.64714470567731 44.6034174805367 -0.0369286659793739 0.970565423959416 6.76281605795925 170.199359462962 0.0397346739687991 0.968329989891371 PLA2G16 other 1 1 1 -0.0369286659793739 0.0397346739687991 0.0235963919851856 72.9178854497155 26.5602117841197 2.74538042250525 0.0063867684123871 70.2587262414769 46.0991136595751 1.52407976344863 0.128479520272707 DIRAS1 other 1 1 1 2.74538042250525 1.52407976344863 0.105208966900256 55.6581940113245 38.7436285928718 1.4365766974538 0.151821380764366 -111.684883881299 96.399354525174 -1.15856464424908 0.24750299515486 PHLDB3 other 1 1 1 1.4365766974538 -1.15856464424908 0.505198779847732 -12.5012009534889 10.9813189846006 -1.13840613964677 0.255810542729728 1.89050233952307 44.4817565603844 0.0425006224058778 0.966126372471242 PRR15 other 1 1 1 -1.13840613964677 0.0425006224058778 0.12428180509544 24.0372019097389 17.9304686272335 1.34057856542747 0.181011219328877 -21.7448165543392 31.120938264148 -0.698719825532693 0.485236220352221 GNG7 other 1 1 1 1.34057856542747 -0.698719825532693 3.06657345228613e-21 220.405620948482 21.4976364417341 10.2525513232981 1.6271676609673e-21 17.9723794328375 88.3111522517859 0.203512002443316 0.838864218161034 USF3 other 4.48731693273029e-17 1 2.43115120225124e-17 10.2525513232981 0.203512002443316 0.114493344200237 40.9254695818128 21.4678567536112 1.90636028791875 0.0574990840144355 -36.9187515633032 52.5972975918538 -0.701913468060404 0.483243326628056 CNTD1 other 1 1 1 1.90636028791875 -0.701913468060404 0.356289735471227 5.48829062964205 8.29468276286733 0.661663717172089 0.508692959004438 -9.04150803994891 15.8656866447108 -0.569878142838723 0.569185432560497 KBTBD11 other 1 1 1 0.661663717172089 -0.569878142838723 4.46486182162344e-11 654.533719828194 91.2777937145585 7.1707881313941 5.31549436345581e-12 -311.463468067294 557.259033012932 -0.558920447432328 0.576611877939592 B3GNT5 other 5.6498361490823e-07 1 7.38215857196743e-08 7.1707881313941 -0.558920447432328 2.3446581850575e-10 94.4895617309556 15.4576033653877 6.11282095273153 2.85487407756224e-09 -204.603923934492 77.7494307694564 -2.63158098920604 0.00891184859696941 RMDN1 other 2.90292129891969e-06 1 3.75273197495557e-05 6.11282095273153 -2.63158098920604 1.69643693693911e-19 327.78717351113 48.6664862679988 6.73537784721208 7.69819254123457e-11 -109.534255914646 76.1377952136597 -1.43863183333938 0.151241431903208 MEX3C other 2.45186030495809e-15 1 1.04803193256367e-06 6.73537784721208 -1.43863183333938 1.70016053115501e-05 283.624551991195 105.339166385245 2.69248904964681 0.00746541668810594 -251.908657554965 170.807593394964 -1.47480947742451 0.141246926521823 RNF152 other 0.158999012873617 1 1 2.69248904964681 -1.47480947742451 1.21146328086154e-05 485.80188204787 123.873122228921 3.92176989896238 0.000107782924472476 -704.325151822595 307.206453099931 -2.29267694319391 0.0225212524589773 MYO1D other 0.114834604392865 1 1 3.92176989896238 -2.29267694319391 0.0159858187268485 25.2403796515587 10.4442834147108 2.41666935387903 0.0162223406355379 -8.83130868744013 26.6685372760262 -0.331150846258788 0.740747290942203 FOXL1 other 1 1 1 2.41666935387903 -0.331150846258788 0.0327503440084563 6.39333168680443 5.20775359476715 1.22765633405324 0.22049261127406 -29.3834028594145 13.0970687381479 -2.24350986063235 0.0255585758146271 LRRC37A other 1 1 1 1.22765633405324 -2.24350986063235 0.285701743439203 22.6928058799318 16.8140656130556 1.34963229014115 0.178087956607142 58.0695264485371 42.9332025720158 1.35255520133006 0.177152733385428 FOXC2 other 1 1 1 1.34963229014115 1.35255520133006 0.257455943729756 -11.4521768735544 10.4510657873955 -1.09579033435674 0.274002338401064 -35.6744342778062 22.3802079118157 -1.5940171073644 0.111928730490238 BDNF other 1 1 1 -1.09579033435674 -1.5940171073644 0.0150320206992064 6.86872813801306 2.40429026595489 2.85686309813557 0.00455849976980051 -1.92493039857228 8.52695468801839 -0.225746526046056 0.821542679753262 CCDC121 other 1 1 1 2.85686309813557 -0.225746526046056 0.00233254544596516 30.0470127933146 17.3108012924779 1.73573783706771 0.0835727993555122 -86.1151613428632 44.1967843720525 -1.94844857078148 0.0522351498010141 ACSF3 other 1 1 1 1.73573783706771 -1.94844857078148 2.95685399232559e-14 384.789845666362 68.9231654324875 5.5828812163782 5.08700154119329e-08 -370.353584743613 124.839205353717 -2.96664484281408 0.00323957674171983 BOK other 4.01156381138813e-10 1 0.000640758714128707 5.5828812163782 -2.96664484281408 0.0665628275158994 3.19978596023204 1.370125854539 2.33539564970011 0.0201625073110774 3.55914898142774 4.78788358234262 0.743365815023914 0.457825052786673 ZNF843 other 1 1 1 2.33539564970011 0.743365815023914 9.53713592132644e-08 143.568276267162 26.7570141481817 5.36563143675426 1.5568380961012e-07 -225.49722998605 131.679281492035 -1.71247311977237 0.0877843241928798 C8orf59 other 0.00105433037610264 1 0.00192394051916186 5.36563143675426 -1.71247311977237 0.000764231434501678 110.972264210607 36.7772528027296 3.01741581422228 0.00275662020696035 -176.746431782169 91.1971781164382 -1.9380690875819 0.0535053097388746 CDK5R1 other 1 1 1 3.01741581422228 -1.9380690875819 0.49518735860962 -7.49730874000947 6.39368549688003 -1.17261143727948 0.241829319208523 -8.78501903605891 13.1518989318931 -0.667965826193769 0.504639904802177 TCERG1L other 1 1 1 -1.17261143727948 -0.667965826193769 0.132638565604418 2.68146021434693 17.5214899299428 0.153038367460094 0.878466630280498 -92.8936256597643 47.0986735106055 -1.972319361369 0.0494531477343788 NCKAP5 other 1 1 1 0.153038367460094 -1.972319361369 2.4010501453565e-18 196.743093145361 33.5065355629382 5.87178261911923 1.07911101038232e-08 -266.914013382454 51.3291065188741 -5.20005181240214 3.56169347287622e-07 RUFY1 other 3.43470223293247e-14 0.00536319803145702 0.000139313231440358 5.87178261911923 -5.20005181240214 3.75461010330934e-07 501.111385865696 91.0484970129995 5.50378537049491 7.76435936383439e-08 -185.568579198077 552.752194713235 -0.335717489632673 0.737309555299069 BASP1 other 0.00400729536326206 1 0.000971321356415683 5.50378537049491 -0.335717489632673 0.016433761517727 -47.7842752521224 71.6693047180202 -0.666732786652914 0.505426283517432 -356.723139090588 138.150749246053 -2.58212960144897 0.0102662111527429 DEFB103A other 1 1 1 -0.666732786652914 -2.58212960144897 0.63385221435032 -4.4110728262918 4.6161647084097 -0.955570934948603 0.340014899349512 -1.14272604585862 10.7146691591585 -0.106650614114563 0.915133412240816 LRRC37A3 other 1 1 1 -0.955570934948603 -0.106650614114563 0.0103157608066594 54.6860173862343 19.1748982992218 2.85195866663103 0.00466067286605595 -169.693982376977 163.601998250369 -1.03723661197148 0.30049870431307 FKBP9P1 other 1 1 1 2.85195866663103 -1.03723661197148 0.0156000910607346 81.9276640355202 28.3431130494319 2.89056688630618 0.00410915865334957 10.2753247821082 78.4212019914477 0.1310273818964 0.895836239522616 VSIG10 other 1 1 1 2.89056688630618 0.1310273818964 0.51980683950115 -3.77678442804218 9.3332504665983 -0.404659067230488 0.686000183654535 -28.0877729133169 24.6965070038395 -1.13731763398565 0.256261752955827 IRX5 other 1 1 1 -0.404659067230488 -1.13731763398565 0.00620154835054716 172.58394237851 94.7184244929279 1.82207361769827 0.0694103573615196 -453.221694154963 208.923600336978 -2.16931784357512 0.0308206773409725 METRNL other 1 1 1 1.82207361769827 -2.16931784357512 4.76511163682495e-14 292.577720320957 35.5848126266642 8.22198288327432 5.15533188670117e-15 166.958455533067 209.412323000536 0.797271398076414 0.425888312061955 FAM91A1 other 6.43718931018683e-10 1 7.42831771554771e-11 8.22198288327432 0.797271398076414 0.000805090783229448 221.572922596232 70.0452848095595 3.16328105737094 0.00171015418356881 -324.758193869935 193.804943691923 -1.67569612871268 0.094777552073282 WSB2 other 1 1 1 3.16328105737094 -1.67569612871268 0.00408382571972715 9.49478597676033 2.84931484741976 3.33230495231458 0.000962847490527511 0.754014120748645 6.00300988545092 0.125606010174345 0.900123176329257 GRIN1 other 1 1 1 3.33230495231458 0.125606010174345 0.604401711491075 17.0858505833127 20.8096248505458 0.821055194700663 0.412231853883845 -23.5987654925086 64.1126244265638 -0.368082974353034 0.71305702654417 SOX11 other 1 1 1 0.821055194700663 -0.368082974353034 5.84141196762089e-13 417.769811738071 54.8841111820828 7.6118534625091 3.69914504175838e-13 -214.721966394175 248.084582199017 -0.865519189023691 0.387459601420505 TYMS other 7.73110873914625e-09 1 5.22023348292943e-09 7.6118534625091 -0.865519189023691 0.999146451906713 -0.683435859556072 17.3653283323258 -0.0393563453841438 0.968631058438144 -0.893184640266714 42.1822564963403 -0.0211744158434058 0.983119844541212 PXMP2 other 1 1 1 -0.0393563453841438 -0.0211744158434058 2.68445381733027e-15 237.428303779129 27.8610385642552 8.5218755658212 6.27647634937205e-16 52.008102417034 86.431572501278 0.601725745719424 0.547782772195933 PNMA1 other 3.70696227635137e-11 1 9.10402894476416e-12 8.5218755658212 0.601725745719424 0.00250717529985977 25.7626171875 7.62082095467123 3.38055668027584 0.000812986238203576 -1.78907738095239 17.4602966798194 -0.102465462858956 0.918451404052169 MAMSTR other 1 1 1 3.38055668027584 -0.102465462858956 4.28711525165877e-09 446.006806388513 96.1729143650431 4.63755111647762 5.16231300897004e-06 -759.256797794588 233.614387480083 -3.25004297031714 0.00127782929744049 ANKLE2 essential 5.06222568915867e-05 1 0.0590929970136801 4.63755111647762 -3.25004297031714 0.111870669609624 -26.8448921657532 28.0424631416622 -0.957294372828123 0.339143626354653 -116.64608072604 59.0025188357851 -1.97696781472478 0.0489060578431113 C8G other 1 1 1 -0.957294372828123 -1.97696781472478 0.917563412883458 -28.1218359374998 70.3526601574209 -0.39972668943256 0.689624505192596 -31.8574702380952 161.187137956592 -0.197642756375973 0.843450065838285 FUT2 other 1 1 1 -0.39972668943256 -0.197642756375973 0.000494133230477207 22.0252411915361 8.80704169511 2.50086714177422 0.0128885290979402 -21.9669561379515 12.1144913321725 -1.81327928145145 0.0707254986351688 GCNT4 other 1 1 1 2.50086714177422 -1.81327928145145 0.633072371043893 65.8899986904071 69.1992960213481 0.952177297729733 0.34172571703616 41.2406354478548 432.610916919939 0.0953296226121057 0.924112682438948 MUC20 other 1 1 1 0.952177297729733 0.0953296226121057 2.22698932497417e-10 201.128438944303 50.7348733571017 3.96430355760708 9.10163009746026e-05 -300.105743267422 91.8951013621992 -3.2657425566633 0.00121124872886648 THAP4 other 2.76013056937298e-06 1 0.947570709446588 3.96430355760708 -3.2657425566633 0.0299684354000326 -4.54220225048138 23.4052544035394 -0.194067629950414 0.846247621617805 113.575816474551 49.72205020545 2.28421426721664 0.0230218321698453 FIBIN other 1 1 1 -0.194067629950414 2.28421426721664 1.27698942344253e-13 348.783542846207 43.5383052236035 8.01095819083744 2.21132474640749e-14 54.1031037084799 210.49128750676 0.257032508800357 0.79732095514418 FAM89B other 1.71244281683644e-09 1 3.16882836160193e-10 8.01095819083744 0.257032508800357 4.24223905513261e-06 469.20282550402 93.386698853043 5.02430036896771 8.44411784536474e-07 -10.5416038425774 196.749501688838 -0.0535788083430528 0.957304383834317 DPP7 other 0.0418157503664421 1 0.0101016981784098 5.02430036896771 -0.0535788083430528 5.87251137589064e-19 520.272206493631 83.631885837148 6.22097901160246 1.54482654614581e-09 -916.513764493803 196.436339715767 -4.66570373801482 4.52712749883791e-06 SEC24C other 8.44936936763145e-15 0.0671916263377522 2.04519586444244e-05 6.22097901160246 -4.66570373801482 5.01399720473941e-09 164.184106013353 34.9419629399822 4.69876595929548 3.89744513295922e-06 -265.007828141341 65.1468087000437 -4.0678558693722 5.98498104608479e-05 SMCR8 other 5.90448310830113e-05 0.860759974047914 0.0449297474927539 4.69876595929548 -4.0678558693722 6.6636317614945e-05 54.0971188474224 29.5424638748636 1.83116476257931 0.068005601858904 -204.076063634656 62.2084170776181 -3.28052172393372 0.00115041212072586 MTHFR other 0.585599959200137 1 1 1.83116476257931 -3.28052172393372 6.44037372770947e-07 114.073350550319 35.0671540842784 3.25299710025403 0.0012638589805459 -106.224496129015 66.036426251604 -1.60857426966582 0.108695565087909 DEAF1 other 0.00675724011511277 1 1 3.25299710025403 -1.60857426966582 4.28875582862227e-08 120.174905438894 31.0789353753888 3.86676390253894 0.000133675714169403 -112.642497531163 42.8963935538182 -2.62591999464572 0.00905816906128793 MTX3 other 0.000482270592928575 1 1 3.86676390253894 -2.62591999464572 0.000511627389813484 -12.6197767338132 20.3508595687663 -0.62011025584303 0.535626532589695 -134.224661570899 38.323555822059 -3.50240625358776 0.000526655414277519 TMEM80 other 1 1 1 -0.62011025584303 -3.50240625358776 0.000313005775395904 84.3958191579179 23.8102104155464 3.54452218964069 0.00045196495569136 -62.3616093534584 57.119993469449 -1.09176499445528 0.275757713802948 SIX5 other 1 1 1 3.54452218964069 -1.09176499445528 4.12322366021417e-05 95.9448352208159 30.6161673516525 3.13379640628458 0.00188535614352469 -181.73999764881 73.4472836932223 -2.47442775975092 0.0138630548896629 FBXO46 other 0.371461219548694 1 1 3.13379640628458 -2.47442775975092 3.76692810867404e-10 36.3516466581225 38.2673451524927 0.949939080259257 0.342860087662234 -448.525123399576 80.3681643831518 -5.58088052454764 5.10601500506696e-08 ZDHHC13 other 4.62880125993866e-06 0.000772999611617086 1 0.949939080259257 -5.58088052454764 6.37973130212856e-14 79.6056390383651 12.370406237102 6.43516773116208 4.53491222891223e-10 -45.8005014506757 20.8800794045353 -2.19350226420726 0.0289947932691868 SLC38A9 other 8.60689549970165e-10 1 6.0863057024231e-06 6.43516773116208 -2.19350226420726 6.64314879193369e-17 29.0087419009957 3.49019876095347 8.31148707790814 2.83251947171593e-15 -24.8536447312689 11.1461116159314 -2.22980404177407 0.0264627379117247 ACER2 other 9.35089623952587e-13 1 4.08959161326346e-11 8.31148707790814 -2.22980404177407 0.00018356402913421 63.0395888449538 22.3098714436317 2.82563657994311 0.00501518372639817 -91.126176320384 43.7182959578666 -2.08439451547258 0.0379170291478018 WDR73 essential 1 1 1 2.82563657994311 -2.08439451547258 0.258337111717909 35.5805200456438 70.6741582778372 0.503444553322704 0.615001402154973 -243.034332520334 171.675157249353 -1.41566395752493 0.157855634154468 POLE other 1 1 1 0.503444553322704 -1.41566395752493 1.90068041338908e-05 103.36322836225 22.7758249885993 4.53828690789423 8.04405459510058e-06 -18.3354394410457 59.2887612289756 -0.309256578497794 0.757328252746309 FAM109B other 0.176763278445185 1 0.0909139050338267 4.53828690789423 -0.309256578497794 1.43778030302797e-10 356.457847195737 56.4033167439243 6.31980294375392 8.80944971494489e-10 183.529135856867 106.647533936426 1.72089432434763 0.0862396255337459 SCN4B other 1.78931758711831e-06 1 1.1743877414993e-05 6.31980294375392 1.72089432434763 1.07092717712457e-13 186.97005060462 53.412530806337 3.5004903864701 0.000530313721588636 -483.776058149385 106.144529663723 -4.55771069580352 7.36864466874239e-06 RHOG other 1.43868356974914e-09 0.10880540717865 1 3.5004903864701 -4.55771069580352 1.54249261780653e-10 303.762766027595 149.145844638268 2.03668273001054 0.0425046845753516 -1169.19213924156 280.862785343731 -4.16285887719393 4.04488305816246e-05 EPS8L2 other 1.9182438195042e-06 0.585213680854944 1 2.03668273001054 -4.16285887719393 0.000172343352647337 362.631173530624 97.0096628451564 3.73809332900624 0.000220045370934618 -310.330138519619 260.313149322615 -1.19214161607725 0.234100203796566 ANO6 other 1 1 1 3.73809332900624 -1.19214161607725 0.0406719905519233 29.0332737043728 11.8405403324739 2.45202270243918 0.0147394739058656 -8.67309561585304 23.1836082393269 -0.374104648694876 0.708574219222971 ZBTB34 other 1 1 1 2.45202270243918 -0.374104648694876 1.52103195551765e-46 236.379220351738 13.7284626199763 17.2181858154883 9.13610428459214e-47 16.1885596678251 58.0942734199735 0.278660162436238 0.780696347518451 FAM210A other 2.32839571750641e-42 1 1.39937709327098e-42 17.2181858154883 0.278660162436238 0.011602283126893 448.57179102421 366.012295179661 1.22556481553174 0.221263709887346 -1024.70141970408 689.253079383713 -1.48668384712957 0.138082930172727 TALDO1 other 1 1 1 1.22556481553174 -1.48668384712957 0.000156406216644634 285.85847932726 94.8589885216426 3.01350967137964 0.00278999610470601 -515.737030850214 228.241040198332 -2.25961566947846 0.0245215823425841 ULK1 other 1 1 1 3.01350967137964 -2.25961566947846 0.132157497767839 -6.71218074301121 5.70895665166258 -1.17572809754239 0.240580270647672 25.1167904054826 17.7640730773731 1.41390942809592 0.158363661802461 RIMKLA other 1 1 1 -1.17572809754239 1.41390942809592 5.19685012546306e-06 57.5076164701335 11.9498231232373 4.81242407331586 2.32646624250811e-06 -40.7882729004995 55.636283186416 -0.73312361222682 0.464033499495034 CLVS1 other 0.0508511784776561 1 0.0271684727800097 4.81242407331586 -0.73312361222682 0.117448746801387 24.6667705040373 25.4860765848477 0.967852796875863 0.333851098185188 -99.8992943810431 66.5486686471731 -1.50114640024864 0.134306835941404 B3GNT8 other 1 1 1 0.967852796875863 -1.50114640024864 0.000464819720461985 125.473756131745 31.8143042213586 3.9439415446184 9.86453340440087e-05 96.6466656345236 76.5486750579504 1.26255177586494 0.207675374565347 PUS1 other 1 1 1 3.9439415446184 1.26255177586494 1.05729846744626e-07 167.600002228189 45.7773795575751 3.66119694591507 0.000294167273115428 -278.000662621265 121.964306712109 -2.279360823798 0.0233120496704165 CHD9 other 0.00116514291112578 1 1 3.66119694591507 -2.279360823798 8.69696707291898e-09 164.616789479351 52.7628843653057 3.11993537615611 0.00197357617664143 -256.206325310872 99.2260442518747 -2.58204715548792 0.0102657937076152 GATD1 other 0.000101284878531214 1 1 3.11993537615611 -2.58204715548792 0.0746206354290045 95.6009679525788 41.8102232710464 2.28654526269374 0.0228964253357958 104.316723709912 143.689739790193 0.725985890587802 0.468395166264995 TRIM72 other 1 1 1 2.28654526269374 0.725985890587802 2.6014298085021e-17 831.463973582279 89.5181451934855 9.2882171741287 2.54622117315268e-18 177.476696701848 188.599133230346 0.941026046419235 0.347405794637832 MAN1B1 other 3.68128332201133e-13 1 3.74956529958464e-14 9.2882171741287 0.941026046419235 0.00437407571170323 -116.229168815923 127.399624084193 -0.912319558644161 0.362289464101645 -745.519231807629 245.217612888332 -3.04023525482701 0.00255970688776251 DEFB4B other 1 1 1 -0.912319558644161 -3.04023525482701 0.231955134292554 -5.49885356956748 3.22606824092691 -1.70450627789186 0.0892571758430019 -5.38801748595912 5.98558025646066 -0.900166275465684 0.368708686148592 KCNA3 other 1 1 1 -1.70450627789186 -0.900166275465684 0.0148143254984998 6.23439712909313 2.13447611606553 2.92080903701324 0.00373928678708594 0.821935107455824 4.0742836354864 0.20173733126896 0.84025025879292 FBXO39 other 1 1 1 2.92080903701324 0.20173733126896 0.000929805777526793 6.57315005219779 3.93130135390078 1.67200360910406 0.0955103161423463 -17.6327873121022 7.33006720008925 -2.40554238191534 0.0167209561940785 CLDN22 other 1 1 1 1.67200360910406 -2.40554238191534 0.0189239955689524 -59.8138874413755 29.6076858029507 -2.02021488067178 0.0441939536367525 -146.669773029934 54.9334875602984 -2.66995196452693 0.00797351367132915 KCNA2 other 1 1 1 -2.02021488067178 -2.66995196452693 6.45842723013715e-12 119.35814300955 22.4917415486385 5.30675415914049 2.09302311427887e-07 -209.740132883396 41.9342549964001 -5.00164204422855 9.40383019755467e-07 TOP3A essential 8.3488088803983e-08 0.0140972818491542 0.00257337191900587 5.30675415914049 -5.00164204422855 8.6509360846144e-11 156.261471094421 22.8285044512354 6.84501568765556 3.94664556998966e-11 -37.128595480448 56.2594198820651 -0.659953400839887 0.509761435164295 CASKIN2 other 1.08439483820642e-06 1 5.40216845620184e-07 6.84501568765556 -0.659953400839887 0.000851383792170876 190.479578202891 50.1522065783608 3.79802986146332 0.000174603542806268 58.5961032392619 250.727658832256 0.233704185298776 0.815364542256055 ZBTB38 other 1 1 1 3.79802986146332 0.233704185298776 0.104083956843547 -6.83547089244201 3.91796690812185 -1.74464742881627 0.0820123477447183 9.64297354145906 12.0468911255019 0.800453282178836 0.42404581333393 RPL13AP3 other 1 1 1 -1.74464742881627 0.800453282178836 9.47016008854412e-30 58.8766326105969 18.0507230538203 3.26173264278941 0.00122716222588127 -224.333679012455 25.4901677863318 -8.80079256021006 8.7446913247495e-17 CCDC71 other 1.43056238297547e-25 1.34318458748152e-12 1 3.26173264278941 -8.80079256021006 0.676593210183849 14.5776234076182 49.2779913679417 0.295824220974676 0.767556197291869 -67.1601732021936 103.87732635913 -0.646533517526278 0.518397330519728 C10orf71 other 1 1 1 0.295824220974676 -0.646533517526278 0.71280917666456 -2.75869264932868 4.39979082575433 -0.627005409707338 0.531112764826894 -11.1411530009002 16.1293743314421 -0.690736836529484 0.490242850533761 LRRN4CL other 1 1 1 -0.627005409707338 -0.690736836529484 2.08881139129575e-18 152.656071947268 16.1671606866421 9.44235508671589 8.22893506673842e-19 -47.2117652124534 30.8800164426629 -1.52887759305811 0.127291998182732 TIMM22 essential 2.98908910094421e-14 1 1.21467310520126e-14 9.44235508671589 -1.52887759305811 2.37884027489527e-17 190.08790586206 20.900741567714 9.09479241424112 1.05426188788306e-17 -58.7797448854583 39.7951594554119 -1.47705765449482 0.140649809731206 HIC1 other 3.36796206119672e-13 1 1.54554792763657e-13 9.09479241424112 -1.47705765449482 0.00111115707301285 116.62796875 35.0351193825423 3.32888743653359 0.00097367144720728 -71.534404761905 80.2700368202616 -0.89117194404785 0.373506497034376 PPFIA3 other 1 1 1 3.32888743653359 -0.89117194404785 8.1925645005498e-18 290.587595386475 31.8022110129744 9.13733939026826 7.8246579797046e-18 325.983095760205 196.747595505885 1.65685936299259 0.0985372748881252 MAGEF1 other 1.16596577971825e-13 1 1.14811206536206e-13 9.13733939026826 1.65685936299259 0.152542423725767 -45.4070640876181 58.373320472023 -0.777873585405865 0.437240650614599 -482.242024674439 252.248175496053 -1.91177606627321 0.0568326509877632 SAMD9L other 1 1 1 -0.777873585405865 -1.91177606627321 0.00206687285314204 249.461749354389 77.6539697310476 3.21247902996322 0.0014498480639589 -251.558499840061 358.487874711676 -0.701721083432415 0.483363156214212 ZFAS1 other 1 1 1 3.21247902996322 -0.701721083432415 2.23152620638232e-12 481.123312675472 67.0653396556586 7.17394879599149 5.15290407778898e-12 -183.589341932566 156.955720892635 -1.16968875609287 0.243002185464114 PAWR other 2.91593529387977e-08 1 7.15789905445667e-08 7.17394879599149 -1.16968875609287 7.66977772883923e-35 579.986482373827 40.5716176721362 14.2953748371771 9.75963101839647e-36 203.110506865691 193.832112442491 1.04786820050756 0.295540006163186 TGIF1 other 1.16649649477916e-30 1 1.48912450078693e-31 14.2953748371771 1.04786820050756 1.07865584727832e-10 61.767540190362 10.1200058948272 6.10350832126833 3.00791552609493e-09 -59.9214925944213 18.8680323771746 -3.17582095454271 0.00164011233881629 MIEF2 other 1.34680969091171e-06 1 3.95149862663091e-05 6.10350832126833 -3.17582095454271 0.0844666843334947 7.86726556032581 5.4278100914273 1.44943640765019 0.148195038880244 -9.60602727990289 10.0198887506863 -0.958696001414676 0.338435680494706 NAP1L5 other 1 1 1 1.44943640765019 -0.958696001414676 1.00467086801576e-07 6.85032510614025 1.19651773595482 5.72521818966078 2.43983284050227e-08 -4.78751200205785 8.42739356439829 -0.568089287093794 0.570385580223246 NIM1K other 0.00110865430285539 1 0.00031117628047766 5.72521818966078 -0.568089287093794 0.13296797376877 -18.2000158385321 9.03253201582722 -2.01494063974988 0.0447521475246469 -17.6227474416044 32.0711428404149 -0.549489225541313 0.583055426393599 CD19 other 1 1 1 -2.01494063974988 -0.549489225541313 0.971768560053897 0.355365644952539 2.76974858480194 0.12830249175051 0.897990441041522 -2.83783678075612 14.8465489846249 -0.191144540303271 0.848533950853511 ERICH5 other 1 1 1 0.12830249175051 -0.191144540303271 3.07468294333205e-19 204.563653829661 47.0444074117009 4.34830971595536 1.84784677238263e-05 -438.587525516766 75.7187041228448 -5.79232741232878 1.66391825095656e-08 NR2C2 other 4.43369280428481e-15 0.000252566151312697 0.203595757381118 4.34830971595536 -5.79232741232878 0.369040424550233 -5.3010751347481 9.1279082703392 -0.580754645834221 0.561814595130204 24.3758233615593 21.8975830827214 1.11317414663874 0.266469128505108 GPR4 other 1 1 1 -0.580754645834221 1.11317414663874 0.420508180197428 -0.427053659255415 4.0193218795269 -0.106250176536168 0.915450436232982 -16.2381336226536 12.4688930613663 -1.30229151398899 0.193753282225307 ACOT4 other 1 1 1 -0.106250176536168 -1.30229151398899 2.56931364362509e-06 2220.37019992932 495.408072581564 4.48190153293022 1.03164972908087e-05 -2811.24839469693 1278.19601313911 -2.19938754760531 0.0285653034893456 CAVIN1 other 0.0257522306500542 1 0.115606668640802 4.48190153293022 -2.19938754760531 4.04920862188723e-24 235.635513636737 49.7959537252664 4.73202129909555 3.35390163718545e-06 -435.082070168109 70.5888768808713 -6.16360663879624 2.15907429731306e-09 ARIH2 other 6.01266988264035e-20 3.29172467368349e-05 0.0388247653520587 4.73202129909555 -6.16360663879624 0.00549240612121842 4.80124354553408 38.4898863189929 0.124740392989025 0.900807401607007 -494.559381085959 157.782229506657 -3.13444284969425 0.00188133198996627 ZBED2 other 1 1 1 0.124740392989025 -3.13444284969425 0.602483799532226 -11.5999728829643 36.782169026772 -0.315369462701376 0.752688006396411 -96.8101743322361 97.3284814585252 -0.994674661327065 0.320650780239482 IRX3 other 1 1 1 -0.315369462701376 -0.994674661327065 0.897953621011412 -0.244611211178088 7.00472105573009 -0.034920906804417 0.972164650351106 -8.36633306382885 18.1232322046488 -0.461635814702126 0.644657142534809 RPRM other 1 1 1 -0.034920906804417 -0.461635814702126 9.82261824964363e-13 298.476230621777 57.7161927451887 5.17144697917828 4.10339373057032e-07 -176.71927916773 107.572705372176 -1.64278920527585 0.101408773396518 SLC25A22 other 1.29462108530303e-08 1 0.0049802889707932 5.17144697917828 -1.64278920527585 0.000619949364911437 47.8025348743196 26.2765569820902 1.81920846429391 0.0698199457361519 -258.198196771305 93.2982258850855 -2.76745023093285 0.00598059172140103 RABEP2 other 1 1 1 1.81920846429391 -2.76745023093285 0.0675124168613274 27.9312493550597 14.3668259663807 1.94414893174182 0.0527563864029348 -7.40352093895278 26.4048643450718 -0.280384736774251 0.779364089020827 NHLH2 other 1 1 1 1.94414893174182 -0.280384736774251 0.000278042923327469 155.68885408029 84.0275776989797 1.85283044381013 0.0648271860716802 -343.436491509904 121.679808105259 -2.8224608245011 0.00506388365412092 ATOX1 other 1 1 1 1.85283044381013 -2.8224608245011 1.60947091162625e-32 1131.98862035514 82.8843930893312 13.6574399372763 1.18360573122867e-33 -338.549045417859 559.410406534848 -0.605189037356189 0.545490522500821 TBL1XR1 other 2.44060169039004e-28 1 1.80298661038064e-29 13.6574399372763 -0.605189037356189 0.0575264910434835 -38.0190200656379 31.1958105571995 -1.2187219817843 0.223850220857268 343.595324290733 172.415552385151 1.99283254635401 0.0471314710585475 SAMD12 other 1 1 1 -1.2187219817843 1.99283254635401 0.495738045357719 20.36334880857 51.0760092284801 0.398687155010054 0.690389633380916 318.690156344171 274.332608842028 1.1616925807303 0.246226108203813 CD163 other 1 1 1 0.398687155010054 1.1616925807303 3.75249304514744e-14 117.49190471566 33.7018098490004 3.48621944168808 0.000558996404850076 -198.705707163899 53.0699650973381 -3.74422155355565 0.000214854172739676 C18orf32 other 5.07899933660705e-10 1 1 3.48621944168808 -3.74422155355565 0.0291497012718248 -18.3390748934995 33.2433090591088 -0.551662136308133 0.581564878061694 -151.161529009854 61.9596082298724 -2.43967857977797 0.0152430095972471 PIDD1 other 1 1 1 -0.551662136308133 -2.43967857977797 0.0311160901059421 1268.59788012535 1189.63508043646 1.06637564828697 0.28705774919019 -2953.89548009893 2217.26794373256 -1.33222305786207 0.183734872195977 RPLP2 essential 1 1 1 1.06637564828697 -1.33222305786207 0.00145175242429663 1718.83288749552 470.747188305832 3.6512865720588 0.000304835462279377 908.452031383235 1128.03096314877 0.805343169701119 0.421221542994075 JUN og 1 1 1 3.6512865720588 0.805343169701119 0.000871429431788217 4.59629596250938 34.2650431374154 0.134139506087197 0.893377114879461 -250.801236446273 72.3655967540675 -3.46575234221606 0.000601386307213759 CSTF2T other 1 1 1 0.134139506087197 -3.46575234221606 0.278493612529977 64.4860491071426 49.2152576874968 1.31028571498317 0.191038916419879 -160.318850977891 166.048064921782 -0.965496653354017 0.335025194003812 PGBD5 other 1 1 1 1.31028571498317 -0.965496653354017 0.378744772616703 -10.9114070219712 8.53051667591886 -1.27910271282552 0.201790540640949 -17.200796025761 21.7264336473066 -0.791699010752889 0.429124488199647 C12orf54 other 1 1 1 -1.27910271282552 -0.791699010752889 6.29410791612952e-05 194.029854930589 43.4549108016173 4.46508464408969 1.11313117144223e-05 0.146180764193251 150.258848491851 0.000972859606342447 0.999224380465629 GBA other 0.554573848490172 1 0.124425802343812 4.46508464408969 0.000972859606342447 0.0118495213474695 0.269084873573428 2.64555406111084 0.101712105425826 0.919048895463738 -13.7288604875963 5.14442946727704 -2.66868475404777 0.00800298577510133 CASC2 other 1 1 1 0.101712105425826 -2.66868475404777 4.81043077914269e-25 341.144235336259 30.2995358603824 11.2590581224815 5.37453222284212e-25 -66.8050981338988 121.576622063224 -0.549489671617605 0.583052711502688 ACAD9 other 7.17235229170175e-21 1 8.09673279371165e-21 11.2590581224815 -0.549489671617605 1.12906284528739e-14 205.612321793229 28.7856130372129 7.14288493795222 6.51324132100136e-12 -196.39651714164 87.4278857325502 -2.24638301036393 0.0253809679681278 IL17RA other 1.54467087863768e-10 1 9.03516836049309e-08 7.14288493795222 -2.24638301036393 3.15774283630998e-06 209.478070660704 72.1125260281872 2.90487772649682 0.00392973856427284 -230.128132558671 134.404906961231 -1.71220037840621 0.0878285327958324 PNPLA2 other 0.0314416454211384 1 1 2.90487772649682 -1.71220037840621 7.99909092400825e-09 314.669215776522 99.0027054811401 3.17839006769836 0.00162562827551014 -866.80243798566 208.472848455392 -4.15786729258958 4.12960835718923e-05 AGTRAP other 9.32694001739362e-05 0.597389144950994 1 3.17839006769836 -4.15786729258958 0.269976524747405 -6.31017921603076 5.61202451613485 -1.12440335887498 0.261687313127506 30.9985664726894 30.5934642831677 1.01324146182897 0.311712738150357 CD163L1 other 1 1 1 -1.12440335887498 1.01324146182897 7.03746736244924e-05 100.269662570122 24.0320403156054 4.17233248834936 3.8916157061814e-05 -27.9061337552511 83.2543282824682 -0.33519138681379 0.737701032472012 SRRM3 other 0.617045138339549 1 0.419088095398675 4.17233248834936 -0.33519138681379 1.31562190572015e-14 84.2735731160338 10.8315674354172 7.78036730311764 1.05956561686816e-13 -68.4693309822985 46.2546649786855 -1.48026866076859 0.139807398677049 THAP5 other 1.79687639883259e-10 1 1.50744400311833e-09 7.78036730311764 -1.48026866076859 0.585075440357178 27.748016796951 33.7265180621522 0.82273588829467 0.411270859862338 -1.56944548127828 62.8602237633165 -0.0249672270844534 0.98009666644815 CRACR2B other 1 1 1 0.82273588829467 -0.0249672270844534 2.19819095131625e-06 5.98434142789625 1.5412447256975 3.88279766874012 0.00012606562642759 -5.4189265686219 2.60254071665823 -2.08216783466121 0.0381417209415993 DNAJC28 other 0.0221401792616573 1 1 3.88279766874012 -2.08216783466121 0.00511198333506593 26.6632968281266 8.28128501956941 3.21970524684501 0.00141751210082999 -43.0426385574593 55.9526536308551 -0.769268940154848 0.442311934919609 NAALADL2 other 1 1 1 3.21970524684501 -0.769268940154848 2.14513359778039e-08 1570.79631398888 350.091548187317 4.48681586894074 1.00952700007287e-05 -464.467508491977 652.50830269955 -0.711818541726423 0.477095753174071 CD151 other 0.000245210221562276 1 0.113258834138175 4.48681586894074 -0.711818541726423 0.000553635149553875 322.044229750268 184.621726438074 1.74434632349887 0.0820588565878728 -622.692976362056 344.102021266484 -1.80961731660339 0.0712932963129664 POLR2L essential 1 1 1 1.74434632349887 -1.80961731660339 0.000956320268860929 190.581743768943 55.1771256740909 3.45399912446749 0.000628457983187901 -226.117402708226 264.967206922036 -0.853378821231862 0.394101849976847 FAM20C other 1 1 1 3.45399912446749 -0.853378821231862 0.00163784308955272 35.592724721716 9.95395313420461 3.57573762321718 0.000403145047861366 12.9871281236284 40.1060657073978 0.32381954935143 0.746286191297979 NECTIN3 other 1 1 1 3.57573762321718 0.32381954935143 0.00194110832392599 12.5352335954545 3.57429746498775 3.5070482292658 0.000519846359789613 -8.72527037185879 25.1880155779275 -0.346405628695293 0.729272141365772 ANXA2R other 1 1 1 3.5070482292658 -0.346405628695293 8.16373590182359e-18 1234.80745637711 134.51255150856 9.17986791960103 5.58156577234846e-18 -445.645058972586 250.789100656273 -1.77697139870277 0.0765257905055687 FLII other 1.16194453090655e-13 1 8.19764564984819e-14 9.17986791960103 -1.77697139870277 8.11817578708918e-07 157.480614433561 31.4033470293558 5.01477165113478 8.8277461441945e-07 -74.0168887164913 118.309045945461 -0.62562324059829 0.532009417404148 SOX12 other 0.00845589189983209 1 0.0105500394169268 5.01477165113478 -0.62562324059829 1.01775504358208e-08 496.673626742768 142.715846401322 3.48015752466691 0.00057063274877761 -780.118460997517 213.012192323464 -3.66231835130305 0.000292369334556045 HNRNPA0 other 0.000118100295257264 1 1 3.48015752466691 -3.66231835130305 0.571924603623436 134.69439061326 256.011107189029 0.526127136014479 0.599164312968213 -397.359704731516 603.678143642698 -0.658231060567771 0.510862936089066 MYOZ1 other 1 1 1 0.526127136014479 -0.658231060567771 0.00258388389900567 -5.47629341142252 2.7300145091227 -2.00595762151548 0.0457021157126219 27.7310687287336 9.55603558489853 2.90194280696874 0.00396577495260721 KCNJ10 other 1 1 1 -2.00595762151548 2.90194280696874 1.49906193152746e-11 316.661914063591 59.3204239880281 5.3381599923746 1.78268982499906e-07 -103.38404873246 110.562706732742 -0.935071614901448 0.350456475349924 CHID1 other 1.918649366162e-07 1 0.00219698694032884 5.3381599923746 -0.935071614901448 0.467601458813309 0.127366369030361 13.7709411325006 0.00924892262662899 0.992626332151286 -25.3650331220123 21.7753481390384 -1.16485086530205 0.244952439918016 PCDHB9 other 1 1 1 0.00924892262662899 -1.16485086530205 2.34246289115183e-07 2.42950742658383 5.83679255770014 0.41624015288649 0.677513309056646 -38.0898846530596 8.3608536842148 -4.55574108717784 7.43377516305473e-06 ZNF620 other 0.00253220238533512 0.10975225650734 1 0.41624015288649 -4.55574108717784 0.52556925514424 34.5157997939926 30.5676927929005 1.12915947002742 0.259676318548278 23.2830385735603 55.9841530939298 0.41588623363644 0.677772015728233 ZNF518A other 1 1 1 1.12915947002742 0.41588623363644 9.23320006149339e-06 41.5920139952539 9.76387893184841 4.25978387130412 2.69605714440421e-05 -50.7359376084924 30.5548368059836 -1.6604879263684 0.0977988960259481 SVBP other 0.0883801909886147 1 0.293654544168507 4.25978387130412 -1.6604879263684 1.94611331584952e-07 9.89711232832897 5.81910688436474 1.70079576213342 0.0899528362089261 -30.7996281710414 8.33552002268711 -3.69498580618999 0.000258575147625002 ZNF619 other 0.00211270061568624 1 1 1.70079576213342 -3.69498580618999 0.755248244810834 3.60888427529725 6.04971082096228 0.596538311020164 0.551240091620462 8.62010998635848 15.4020598993811 0.559672540080488 0.576096807372367 CCDC184 other 1 1 1 0.596538311020164 0.559672540080488 9.16822241988419e-11 372.162133974458 67.0581040460698 5.54984575344955 6.00546297782803e-08 -180.446789558264 99.1001866711683 -1.82085216607127 0.0695631192968642 AP3S1 other 1.1476780825211e-06 1 0.000754226095385422 5.54984575344955 -1.82085216607127 1.35691144881127e-11 538.322772077748 74.9735713412509 7.18016712352555 4.90043501155039e-12 -75.5399593131612 185.94497306914 -0.406248999724628 0.684831191929087 GRB2 essential 1.73901771279653e-07 1 6.81160466605504e-08 7.18016712352555 -0.406248999724628 2.45290591958464e-06 120.329201508959 23.2916695483219 5.16619048107818 4.2255367485184e-07 -31.4809732161345 80.1420063291833 -0.392814887698548 0.694719392339794 ZBTB41 other 0.0246271754326298 1 0.00512642118330253 5.16619048107818 -0.392814887698548 0.00210275306144085 172.373283287765 67.1109043900169 2.56848398713289 0.0106691353439961 -321.591118275323 163.264440120961 -1.96975604753282 0.0497311900152266 UBE2N essential 1 1 1 2.56848398713289 -1.96975604753282 1.28959253667528e-07 105.998551543512 25.5781458331273 4.14410615355195 4.37532178227824e-05 -213.64622894041 66.1780351580068 -3.22835557795435 0.00137455628914997 ARL6IP6 other 0.00141365133870345 1 0.469340767584987 4.14410615355195 -3.22835557795435 0.414562051327132 0.901182858839422 15.5506061891621 0.0579516224562035 0.953823333680775 -29.3889479945133 23.9042063474532 -1.22944671608579 0.219807573307371 ZNF354C other 1 1 1 0.0579516224562035 -1.22944671608579 7.61916742159744e-05 50.8545935412027 19.4252178735627 2.61796772999982 0.00926735224466883 -129.607754647516 40.5290286212821 -3.19789935896609 0.00152320204747945 MAMDC4 other 0.665000932557024 1 1 2.61796772999982 -3.19789935896609 3.3494210695577e-06 48.8477188862138 11.5489865479644 4.22961085661872 3.06465226561191e-05 -21.1486824107727 29.4862443160903 -0.71723893297703 0.47375317606142 CENPBD1 other 0.0332764983260557 1 0.332514770818892 4.22961085661872 -0.71723893297703 1.51183621116779e-20 302.370989091096 46.4943821567121 6.50338761513028 3.05526856503352e-10 -229.283514951663 87.2523088105237 -2.62782175139426 0.00901142272917374 BET1L other 2.20244299242924e-16 1 4.11178043482211e-06 6.50338761513028 -2.62782175139426 2.51607877293825e-08 158.579680148613 26.1926701382636 6.05435334815109 3.94674870218508e-09 -63.5642019103853 93.1746144668944 -0.682205150770655 0.495602739534894 RPS27 essential 0.000286581372237667 1 5.16629405116026e-05 6.05435334815109 -0.682205150770655 4.78948216953172e-08 155.731748628926 57.7455893084235 2.6968596302161 0.00737032809499696 -443.415502098885 112.290610409465 -3.94882083623895 9.66266635193047e-05 IMP3 essential 0.000537044635669592 1 1 2.6968596302161 -3.94882083623895 0.0240718234006961 52.7537258263064 26.8275580254022 1.9664005861568 0.0501218134416393 -102.817235179927 68.3007283967407 -1.50536074202151 0.13322396065507 ASB8 other 1 1 1 1.9664005861568 -1.50536074202151 0.00290510869281605 5.21644278257356 69.8994981675637 0.0746277572704264 0.940557959354321 -662.928986621073 199.468588574985 -3.32347559762203 0.000993119534676336 ODF3B other 1 1 1 0.0746277572704264 -3.32347559762203 0.764483201915575 0.852498251566551 2.71824638516211 0.313620669642023 0.754014775664434 6.3897974281393 9.13208256125349 0.699708679294094 0.484620777569038 DPY19L2 other 1 1 1 0.313620669642023 0.699708679294094 0.0271260817103421 16.5446094054898 13.1991991997184 1.25345554341226 0.210960742133386 -83.1119763887081 39.5224326757428 -2.1029063942139 0.0362595306595299 LRRC75B other 1 1 1 1.25345554341226 -2.1029063942139 1.6518480897186e-05 105.580178798868 29.2708055560182 3.60701309011839 0.000359228108604163 -227.148710978762 91.7963403766233 -2.47448547563893 0.0138608582332408 DMAP1 essential 0.15467905512125 1 1 3.60701309011839 -2.47448547563893 0.339581993303214 -2.08025637240515 4.96822177576352 -0.418712462183808 0.67571073000847 24.7296993946701 18.5131406336788 1.33579168894133 0.182578619664352 ADAMTSL1 other 1 1 1 -0.418712462183808 1.33579168894133 1.6018262451033e-15 1259.42844881187 254.112062223939 4.95619309760269 1.1709445605855e-06 -1233.22270957801 360.216144849292 -3.42356312234135 0.000698994047560816 IMPDH2 essential 2.21981081046415e-11 1 0.0139155051579981 4.95619309760269 -3.42356312234135 5.61878665306622e-13 101.205054654605 121.230926653041 0.834812184058037 0.404446266196166 -1073.01599582023 173.518941016192 -6.18385514305382 1.90698982151796e-09 ALS2CL other 7.43871164999437e-09 2.90796877883274e-05 1 0.834812184058037 -6.18385514305382 3.8180863122227e-09 188.670642815554 29.7896652018976 6.33342609045287 8.29305008995647e-10 201.647051439283 172.641124241223 1.16801284934597 0.243687669427152 MLF1 other 4.5175597246219e-05 1 1.10620995149929e-05 6.33342609045287 1.16801284934597 8.03606451679785e-13 162.908971101078 42.2644227346223 3.85451783226715 0.000140312019777653 -220.680922386526 59.9118644290478 -3.68342605408105 0.000270354160575187 NDUFAF3 essential 1.06084087686248e-08 1 1 3.85451783226715 -3.68342605408105 1.67991913364888e-12 121.017226480064 17.247163838259 7.01664503305841 1.40453893241788e-11 -41.0201368598638 39.9517628763702 -1.0267415980316 0.305332444656272 C2orf69 other 2.20237398421368e-08 1 1.93826372673668e-07 7.01664503305841 -1.0267415980316 5.48323732531227e-07 48.3442857142858 9.1227336187459 5.29932010893591 2.16883846420232e-07 -7.63790410281763 37.7558135512749 -0.202297431425888 0.839812759525118 GRAMD1C other 0.00578152543580925 1 0.00266463493711897 5.29932010893591 -0.202297431425888 5.60832234565125e-06 -5.3841688790041 100.845061225301 -0.0533905063231127 0.957454084349337 -836.46871055389 186.872119679392 -4.47615573681607 1.05810540617906e-05 STAP2 other 0.0547484427382475 0.155657886303001 1 -0.0533905063231127 -4.47615573681607 1.45693313824654e-05 4.38162308721351 1.88305200070943 2.32687312169964 0.0205997649806597 -14.1502151671513 4.28323473682804 -3.30362822412816 0.00106325688704759 TSSK6 other 0.137126546971764 1 1 2.32687312169964 -3.30362822412816 1.26062030797252e-18 176.465533167784 18.1767169990659 9.70832814181201 1.17288012393532e-19 -22.4862888157304 75.2723908961085 -0.298732225030107 0.765341969519336 BOLA1 other 1.80810770772499e-14 1 1.73762190361018e-15 9.70832814181201 -0.298732225030107 4.69914906594964e-21 175.143217117483 30.8542161660882 5.67647598547592 3.12152981208178e-08 -181.029332463435 56.6076271279304 -3.19796715828271 0.00152466761363424 DDX10 other 6.86921610460519e-17 1 0.000396246994345661 5.67647598547592 -3.19796715828271 3.27493300259093e-13 39.0975393591527 5.27748279411738 7.40836889183861 1.16040728490032e-12 -43.2591029103895 24.6439012551838 -1.7553674827069 0.0801593223443933 PPP1R42 other 4.3559883867462e-09 1 1.62770329852968e-08 7.40836889183861 -1.7553674827069 7.75125880549157e-34 427.585510396931 31.2512734054516 13.6821787979475 8.29863323889992e-34 -19.7085164787091 131.875396829844 -0.149448016479817 0.881295159556113 NDUFV2 other 1.17733869996611e-29 1 1.2642967739464e-29 13.6821787979475 -0.149448016479817 6.69721510179281e-17 176.814630585818 53.9416752158322 3.27788541750594 0.00116159949772119 -419.740930226271 76.4649348909545 -5.48932567358956 8.25886549680437e-08 DALRD3 other 9.42499081275302e-13 0.00124890564042676 1 3.27788541750594 -5.48932567358956 0.151727633818598 30.0177539062499 16.0844003352113 1.86626503199727 0.0629188719553707 -4.63808035714288 36.8514630431822 -0.125858784811556 0.899922744539721 ZNF114 other 1 1 1 1.86626503199727 -0.125858784811556 0.0015687101690563 120.634845135631 38.3376579189497 3.14664097088735 0.00180686845150821 22.251830701008 71.8468425737301 0.30971201939978 0.756981545326311 ZNF518B other 1 1 1 3.14664097088735 0.30971201939978 0.492511029049815 120.89374711523 127.439183339923 0.948638746316867 0.343520230501741 -64.7988313252649 184.748249479325 -0.350741246576827 0.726013261252685 SPINK6 other 1 1 1 0.948638746316867 -0.350741246576827 0.0574878982220701 -4.51019326205213 3.87010970089084 -1.16539158076422 0.24473118448902 -12.6507082362164 5.29881532780802 -2.38745973459876 0.0175471661317221 ZNF366 other 1 1 1 -1.16539158076422 -2.38745973459876 1.6714397034708e-07 10.4978866117239 18.4017767475823 0.570482228739303 0.568753538645181 -151.790513269005 34.5491439393733 -4.3934666958859 1.52174366033666e-05 LCORL other 0.00182120070090178 0.22298109854913 1 0.570482228739303 -4.3934666958859 2.03320863157738e-21 224.983637407694 56.1738343716137 4.0051322813275 7.76468423262554e-05 -414.290596899146 82.9980043320022 -4.99157299303165 1.00071337226661e-06 PARD6G other 2.97844732439771e-17 0.0149946891700429 0.814204788633115 4.0051322813275 -4.99157299303165 0.0262989503704072 30.2143166146198 36.5091305003187 0.827582475960528 0.40852760513485 -289.860737933759 129.630267260983 -2.23605755089732 0.0260413826493029 SH2B1 other 1 1 1 0.827582475960528 -2.23605755089732 0.018712193764487 -13.4040363453108 4.94738520971405 -2.70931730138829 0.00710525341075958 2.04870750317288 10.8439338476237 0.188926595455193 0.850270113499604 ZC3H12D other 1 1 1 -2.70931730138829 0.188926595455193 9.60992952063214e-10 264.003717972237 62.4279066437885 4.22893754036369 3.07840189580855e-05 -150.066356326057 114.627978549123 -1.30915992958688 0.191431337243653 KDELC2 other 1.16241707481566e-05 1 0.333945037657311 4.22893754036369 -1.30915992958688 1.15874967879257e-10 7009.50576008552 1021.2973226494 6.86333509805138 3.49654362536727e-11 -3114.15322778533 5032.9579751298 -0.618752082408361 0.536519894379849 PLEC other 1.44484497448646e-06 1 4.79201303856584e-07 6.86333509805138 -0.618752082408361 0.0128218757821447 -63.5505690019326 27.7932207157778 -2.28654928667033 0.0228812389488438 -145.475641070074 51.2710713628515 -2.83738250836472 0.0048415238887021 RNF212 other 1 1 1 -2.28654928667033 -2.83738250836472 0.107311406577428 -17.593119996412 8.29735791634117 -2.12032796147836 0.0347698235472216 -17.8172919516516 28.5243106696137 -0.624635321008194 0.532668410389408 PRSS36 other 1 1 1 -2.12032796147836 -0.624635321008194 0.00010017126563451 21.1175875822432 5.83468403488378 3.6193198219454 0.000343369983837971 -16.0952631335893 14.502792999164 -1.1098043759238 0.267919228091123 ZNF543 other 0.862975453441305 1 1 3.6193198219454 -1.1098043759238 0.0724182147887116 16.8158015575609 9.51823446337488 1.76669335287613 0.078235847148835 -23.3643064724581 26.4609966045886 -0.882971523015368 0.377916564831757 TMEM151B other 1 1 1 1.76669335287613 -0.882971523015368 0.000244270818641877 170.80333466598 75.3449437463107 2.26695151888468 0.0240643675037176 -302.703359713304 167.502468854955 -1.80715760061676 0.071682693422523 GALNT11 other 1 1 1 2.26695151888468 -1.80715760061676 1.07045597599407e-18 472.51612554405 145.661445033768 3.24393407901802 0.00130423483839569 -1243.78980022168 206.482146986795 -6.02371594044507 4.70774246132213e-09 WDR6 other 1.53578318875869e-14 7.16753789736294e-05 1 3.24393407901802 -6.02371594044507 0.0156375249595439 29.3981939942293 24.860490228535 1.1825267210735 0.2378829599945 -182.872275852243 78.4873525827005 -2.32995851987177 0.0204358294473799 GEN1 other 1 1 1 1.1825267210735 -2.32995851987177 3.12848129481607e-06 6.24230952833316 2.12049717609562 2.94379525646285 0.00348008389662268 -8.2397830944117 3.68043150898694 -2.23880897505949 0.0258575844532715 TMPRSS9 other 0.0311690591402525 1 1 2.94379525646285 -2.23880897505949 2.65244766275073e-13 5.21247202662637 0.837319544771801 6.22518853067852 1.53384539818069e-09 -3.92624561691087 2.67639838056649 -1.46698848923972 0.143376840251586 AQP11 other 3.53730420304438e-09 1 2.03096469173105e-05 6.22518853067852 -1.46698848923972 5.41292418995961e-12 137.376479808745 19.1349794545732 7.17933772204354 4.92610248628593e-12 -57.4846055477029 35.3758196633053 -1.62496886559298 0.10515366437743 TMEM11 other 7.01136070325468e-08 1 6.84580462519156e-08 7.17933772204354 -1.62496886559298 4.58353535794244e-05 25.6266549673855 8.16007227142053 3.14049362738357 0.0018440479870288 -25.3750053214384 12.6782471626134 -2.00146005957876 0.046186825598473 ZNF354B other 0.41091394483954 1 1 3.14049362738357 -2.00146005957876 7.01206583498482e-05 4855.24535655787 1567.33874781272 3.09776387735806 0.00212319051917837 -4164.00227743977 3212.12046726357 -1.29634063226375 0.19579517766894 CALML3 other 0.615098415044869 1 1 3.09776387735806 -1.29634063226375 7.00198387031677e-07 3570.72286084787 777.355328171097 4.59342430860903 6.28545101046544e-06 -556.829160870825 1593.12016208325 -0.349521131000366 0.726928733201846 CALML5 other 0.00732407512835135 1 0.071559859754149 4.59342430860903 -0.349521131000366 1.7411569124606e-08 131.508235753425 21.5669788348928 6.09766610150609 3.14712528210038e-09 34.4053953739013 104.055304999187 0.330645279201962 0.741132257989154 ZFAND2A other 0.000199971871396099 1 4.13280492045421e-05 6.09766610150609 0.330645279201962 1.56094155342609e-05 46.7187729033605 20.0550015976067 2.32953224540933 0.020460679934632 -106.505427005899 37.7450250521741 -2.82170767826167 0.00507933189005461 PLEKHM3 other 0.14646314595797 1 1 2.32953224540933 -2.82170767826167 1.11146846263134e-20 24.7498393153357 2.45108667860783 10.097496564011 5.51784844866275e-21 -4.25483882141487 10.3224599384546 -0.412192330780008 0.680475310622566 ZNF223 other 1.62085445905529e-16 1 8.22435311273182e-17 10.097496564011 -0.412192330780008 1.87540008600444e-20 141.845414748324 14.0732868663952 10.0790537487748 6.36232754587996e-21 -21.9509998538019 67.3643011927771 -0.325855081476828 0.744747649542967 FAM220A other 2.72964482517946e-16 1 9.4817767416249e-17 10.0790537487748 -0.325855081476828 0.305921452109155 13.751988558541 9.42534540705373 1.45904345831711 0.145540189474861 -4.50865083886665 24.955603320679 -0.180666873925289 0.856744146295942 DNAJC22 other 1 1 1 1.45904345831711 -0.180666873925289 0.017527303111684 45.745056682929 16.122875165061 2.83727661565356 0.00484122447305483 35.1302295013891 37.9050808729932 0.926794738127543 0.354733764810492 CEP295NL other 1 1 1 2.83727661565356 0.926794738127543 0.0110331633300994 24.8636742852545 9.14868997378238 2.71773055557757 0.0069322687908084 -11.3697534863827 20.7550956814681 -0.54780539973779 0.58420862384487 BEND3 other 1 1 1 2.71773055557757 -0.54780539973779 0.0492245130260103 -32.4828619017008 44.5534039364533 -0.729076995958182 0.466489502710677 -255.984921980014 103.925029423865 -2.46316910756851 0.0142991682986536 NT5DC1 other 1 1 1 -0.729076995958182 -2.46316910756851 0.00326179385404344 72.7259771466977 21.6928419800231 3.35253339390343 0.000898679905119745 88.4056746765249 72.9959555145591 1.2111037392872 0.226766364357322 GLDC other 1 1 1 3.35253339390343 1.2111037392872 0.87197215361431 15.7480574206885 35.2085298912815 0.447279607223478 0.654976736925805 -16.7387604965273 96.0114545780045 -0.174341286361075 0.861707844920618 COX14 other 1 1 1 0.447279607223478 -0.174341286361075 0.00368637453454828 20.2153617756577 7.96307185475044 2.53863862393732 0.0116064857096647 -68.2751770546863 37.0841073771234 -1.8410899407762 0.0665426805120521 MCMDC2 other 1 1 1 2.53863862393732 -1.8410899407762 7.26413388762363e-05 19.3419139915203 4.78437928642949 4.04272170611182 6.62467042815582e-05 3.67904973416782 9.79039792902648 0.375781430013198 0.707328381648506 TUBAL3 other 0.635974921861449 1 0.699300210396129 4.04272170611182 0.375781430013198 0.000818058180537326 -21.4657889756966 43.0193208832456 -0.498980191573799 0.61813833549368 -211.248100889405 60.9819690847304 -3.46410757245129 0.000604939769386097 P4HTM other 1 1 1 -0.498980191573799 -3.46410757245129 1.02101774813903e-05 110.012983195717 23.4521039582082 4.6909643327422 4.0342797666527e-06 -34.2484269268974 76.8395900269148 -0.44571329590516 0.656105758445614 DTX3 other 0.0973846728175006 1 0.0464668343523058 4.6909643327422 -0.44571329590516 0.0166717149031739 10.498091894928 4.15246147694483 2.52816117698265 0.0119468498276444 -12.4047068952808 10.7137125902824 -1.15783457795313 0.247794990877939 KLHL11 other 1 1 1 2.52816117698265 -1.15783457795313 0.0174346809705332 50.2781409582281 32.3735863508721 1.55306058504926 0.121400176214083 -92.5064247411151 60.2558551971549 -1.5352271482736 0.12571923881051 CTXN1 other 1 1 1 1.55306058504926 -1.5352271482736 5.39641527394669e-08 2.92085895100853 15.6346493583425 0.186819600751071 0.851921207973663 -108.618271493512 22.0550003113161 -4.92488188439431 1.35924399371616e-06 SLC25A20 other 0.000603755425474675 0.0203302124140127 1 0.186819600751071 -4.92488188439431 0.509019096620713 -1.5943553063986 4.11070808618334 -0.387854178154233 0.698388428531007 19.6523459722184 19.1387367679823 1.02683610786138 0.305293065339563 CA8 other 1 1 1 -0.387854178154233 1.02683610786138 0.0265237034025265 -17.5957308313267 6.69160027739784 -2.62952509144332 0.00896871370104313 -22.1659203214943 14.5320443277399 -1.52531328845331 0.128181170076358 CD28 other 1 1 1 -2.62952509144332 -1.52531328845331 4.01023529012654e-07 61.6863592747334 33.7118007114202 1.82981501945806 0.068207800936621 -167.289520820423 48.2901234527775 -3.46425953919986 0.000604136567080309 EPM2AIP1 other 0.00426648932516563 1 1 1.82981501945806 -3.46425953919986 0.758504703130849 4.35192919422387 6.22615383287614 0.698975533056098 0.485079829041249 0.867461152939552 11.1910237816809 0.0775140121102715 0.93826354660791 ERBB4 other 1 1 1 0.698975533056098 0.0775140121102715 0.000483550451391522 508.862226988294 154.201835172325 3.29997516838647 0.00107636947045254 -177.873751944538 395.372071866539 -0.44988952078684 0.653095660488076 MAF other 1 1 1 3.29997516838647 -0.44988952078684 3.70898946681221e-14 545.545459844213 87.5846751546323 6.22877756732034 1.48272118166691e-09 -685.038492878575 198.120261349222 -3.45769023427177 0.000618750982649993 CTNNBIP1 other 5.02048814227701e-10 1 1.96356766088149e-05 6.22877756732034 -3.45769023427177 7.44749568459236e-05 62.5296336006016 16.3208089852689 3.83128272973728 0.000153512237389893 10.7547529340873 30.2825665972723 0.355146678189954 0.722714405991637 PSAPL1 other 0.65113454770391 1 1 3.83128272973728 0.355146678189954 0.0924309247856998 33.3585963471022 19.9481531237634 1.67226490292796 0.0954556519914524 -55.5040053876424 45.8567595607992 -1.21037783566134 0.227032823072728 ERN1 other 1 1 1 1.67226490292796 -1.21037783566134 0.396968591320331 0.782318531770751 4.15851103412111 0.188124673795916 0.850898159110296 -8.40191685719212 7.53134139933756 -1.11559367869463 0.265433155634046 GPR35 other 1 1 1 0.188124673795916 -1.11559367869463 0.452423361803235 5.97166384112375 5.22933274651617 1.14195522270066 0.254339935332596 -4.85593623499287 14.8265387463298 -0.327516510635021 0.743494814862229 CSRNP3 other 1 1 1 1.14195522270066 -0.327516510635021 1.73787236998861e-19 26.4655827761145 2.6422493709472 10.016307721412 1.86088012009354e-20 -11.1030048646534 23.4864853845735 -0.472740160260256 0.636756626800834 ZNF713 other 2.51139936187054e-15 1 2.76880353068718e-16 10.016307721412 -0.472740160260256 0.00194426973887771 174.918185531716 63.0209233408244 2.77555732698073 0.00583595460910201 -589.486500616703 310.530884830205 -1.89831842632667 0.0585565253375234 PARP10 other 1 1 1 2.77555732698073 -1.89831842632667 0.889739851907382 33.7113493925802 71.9694438473638 0.468411975839035 0.639809907837363 21.2325224502728 110.818492275558 0.191597286827153 0.848179563831383 DYNAP other 1 1 1 0.468411975839035 0.191597286827153 0.000947754796439644 87.1953533254506 45.459901257621 1.9180717712367 0.0560057794223508 -332.125295897283 112.730048730167 -2.9462002335532 0.00345692201915623 SUZ12 og 1 1 1 1.9180717712367 -2.9462002335532 1.89751728273872e-11 44.7345310178615 6.60688563702235 6.77089531672639 6.60943474727689e-11 -24.6894122894225 26.3622479354902 -0.9365442715598 0.349736427624458 NSUN3 other 2.42445783215526e-07 1 9.0086595605384e-07 6.77089531672639 -0.9365442715598 0.000503178633894789 233.325461118452 64.7784124665057 3.60190150135426 0.000370755952520251 -77.6738037997111 132.637578948037 -0.585609330445794 0.558587318207455 KCTD12 other 1 1 1 3.60190150135426 -0.585609330445794 3.89010387735366e-15 58.8824425969913 7.17036455309972 8.21191756164429 6.35588761219879e-15 -10.8988514322837 28.6162187804057 -0.380862737873197 0.703571992999845 DHFR2 other 5.35667303911599e-11 1 9.1505713952826e-11 8.21191756164429 -0.380862737873197 0.161854693500347 9.50423124465194 55.0659218791773 0.172597332802411 0.863077059931702 -183.267566796614 108.191819585179 -1.69391334297995 0.0912547814984513 RPP25 other 1 1 1 0.172597332802411 -1.69391334297995 2.24511112585916e-14 868.888638176196 105.33929893066 8.24847561163419 4.25705011529344e-15 -111.083668546881 519.051514485531 -0.214012801132049 0.830673802164595 GRINA other 3.05380015339363e-10 1 6.13909197126467e-11 8.24847561163419 -0.214012801132049 0.278275393577171 321.601686732416 224.361833285614 1.43340639547643 0.152730390265288 -265.703633846196 958.677188332824 -0.277156520547094 0.781841139783245 THBD other 1 1 1 1.43340639547643 -0.277156520547094 0.00287690774833284 88.7450793952656 103.420731287006 0.858097581508939 0.391480833211887 -560.560578111626 203.197853026449 -2.7586934102038 0.00613716022495406 COX5A other 1 1 1 0.858097581508939 -2.7586934102038 0.0100805998544672 12.3902612826603 4.47758085748468 2.76717756239932 0.00600209471299115 -9.53661611547595 17.8695842416196 -0.533678679175113 0.593955137043316 STX19 other 1 1 1 2.76717756239932 -0.533678679175113 0.141856774795889 -14.6758642324882 7.78112458359626 -1.88608524061253 0.0601945927475633 -4.10733444965485 14.0835897290267 -0.291639740199866 0.770752238447407 ERFE other 1 1 1 -1.88608524061253 -0.291639740199866 0.000488642830934621 54.8801464295904 30.0324158707591 1.82736369480766 0.0685762930353845 -149.549034895882 59.0067615089707 -2.53443895362985 0.0117391264231257 FAM219B other 1 1 1 1.82736369480766 -2.53443895362985 0.661335446072128 27.5174295913128 31.5692579518375 0.871652720925332 0.384053400806858 -36.962182690054 178.511279225381 -0.207057967711873 0.836096694898402 ZHX2 other 1 1 1 0.871652720925332 -0.207057967711873 0.301502684269974 16.4457641409048 11.0176329851471 1.49267670860659 0.136507073921342 8.00315624065542 28.230213766722 0.283496126058018 0.776979873728763 CPNE7 other 1 1 1 1.49267670860659 0.283496126058018 0.085855858125485 25.6601961384273 11.9367018120719 2.14968896286547 0.0323291303505662 3.5012857441935 17.3046052755591 0.202332598082355 0.839785292191016 C5orf46 other 1 1 1 2.14968896286547 0.202332598082355 0.905255262462711 -0.135785580549035 1.09699985002686 -0.123779032919385 0.901568187777231 1.05433520509744 2.5937713675732 0.406487332799847 0.684657129678401 CD300LB other 1 1 1 -0.123779032919385 0.406487332799847 4.94620482734187e-11 207.001759056766 43.4786675096561 4.7609959300338 2.92325499051626e-06 -265.004839783207 85.425540706102 -3.10217339677052 0.00209218901617344 MPI other 6.25101366079465e-07 1 0.0339419136948843 4.7609959300338 -3.10217339677052 0.0132649192254825 -8.63532781836117 3.08353691493011 -2.80046195540905 0.00541418402554317 -13.7380309033516 9.23368300066517 -1.4878170392423 0.137786960867453 ADORA2A-AS1 other 1 1 1 -2.80046195540905 -1.4878170392423 0.0182317909841231 -9.10900945598019 4.38361878089629 -2.07796569712609 0.0385195047134446 -37.5313772716768 15.4082383873391 -2.43579936448259 0.01541131004369 TRIM73 other 1 1 1 -2.07796569712609 -2.43579936448259 1.55105574302692e-05 109.759652979051 23.5932083835255 4.65217155695081 4.82001482263722e-06 195.250954033697 116.253769175952 1.67952364398767 0.0940291136122787 OPLAH other 0.145582092040507 1 0.0552277298377773 4.65217155695081 1.67952364398767 0.13460524550832 26.104654985505 14.8893208630684 1.75324685562087 0.0805201278248087 -15.1113384611623 33.0940421704841 -0.456618094076153 0.648256321044507 TMEM52 other 1 1 1 1.75324685562087 -0.456618094076153 0.0783739174692308 18.7213671176722 10.6080372626607 1.76482855915012 0.0785464449932298 -8.3950923677907 23.1249656126651 -0.363031561145019 0.716820988963294 TMEM139 other 1 1 1 1.76482855915012 -0.363031561145019 0.878213873857734 -0.861865499725458 2.24918424956864 -0.383190261042754 0.701834728342813 -1.94612840583664 5.36454405988558 -0.362776106247164 0.717013143072259 EFCAB13 other 1 1 1 -0.383190261042754 -0.362776106247164 3.34515618982184e-05 152.588956882183 33.4310349648278 4.56429054747241 7.17817794259535e-06 194.673991109317 154.640747915254 1.25887900656043 0.209000295404738 MSC other 0.304007794531009 1 0.0813861815131461 4.56429054747241 1.25887900656043 6.09764077643533e-22 408.399280654922 39.9346851226157 10.2266808765606 2.06608117006956e-21 -111.476844230845 158.710941714583 -0.702389154941303 0.482950317059284 APOLD1 other 8.95926359281643e-18 1 3.08527901126487e-17 10.2266808765606 -0.702389154941303 0.0782070163164326 33.2437337232897 20.1924403537557 1.64634552044654 0.100674352586446 94.730003454781 51.8041459914522 1.82861818570297 0.068387508513202 RFLNA other 1 1 1 1.64634552044654 1.82861818570297 0.00016975097637736 52.0562443642923 15.7885660739749 3.29708499938441 0.00108713443387015 -82.5736868800719 47.7798850625505 -1.72821024521033 0.0849182263944234 DPY19L3 other 1 1 1 3.29708499938441 -1.72821024521033 0.000216768847905305 281.187998042902 79.8657929589096 3.52075635419499 0.000493203658249775 -121.309121099325 126.288060441721 -0.960574742180845 0.33749582972936 TAF7 other 1 1 1 3.52075635419499 -0.960574742180845 3.49761652981755e-06 2.78028379712107 1.60547634958459 1.73175008018053 0.0842847944135054 -7.33588452792552 2.30098781262814 -3.18814575534263 0.00157386486063723 ZNF852 other 0.0346998535923199 1 1 1.73175008018053 -3.18814575534263 0.410698571455404 75.7837416397493 154.691576540132 0.489902186885326 0.624538804964016 -346.984368090912 296.133105946642 -1.17171758619056 0.242182116798557 FOXE1 other 1 1 1 0.489902186885326 -1.17171758619056 3.83642698014964e-12 163.535503608078 21.8995808912453 7.46751750274152 7.87501191691613e-13 -37.6460031451553 41.5329389834774 -0.906413176301625 0.365401338214889 PFAS other 4.98697143149651e-08 1 1.10643917432672e-08 7.46751750274152 -0.906413176301625 0.000124488961303301 66.9763192862068 21.6024584878933 3.10040263814151 0.00210436718939426 -164.189914898903 68.1329000458804 -2.40984773565104 0.0165231698106813 HYI other 1 1 1 3.10040263814151 -2.40984773565104 0.013845599176447 135.271170459629 45.9386508766489 2.94460476914852 0.00347276273313418 60.6236289018501 102.894990928196 0.589179593243327 0.556160436649552 C17orf62 other 1 1 1 2.94460476914852 0.589179593243327 0.00312798088054678 27.2015237560425 8.63559006310311 3.14993226372164 0.00178774381435347 -9.59587932521695 22.6999862993618 -0.4227262166007 0.672779831711982 ZNF552 other 1 1 1 3.14993226372164 -0.4227262166007 5.84778681331859e-21 293.74392772391 64.5079388084314 4.5536089534071 7.52899053498578e-06 -639.460934887913 118.999923324467 -5.37362476397863 1.49779981911735e-07 GAK essential 8.54361653425847e-17 0.00226137816690338 0.085235701846574 4.5536089534071 -5.37362476397863 3.25575450669582e-08 132.531520483008 54.8390400160534 2.41673669787456 0.016221158302347 -383.048434167656 101.464430393963 -3.77519917748877 0.000190638895061907 ZBTB7A other 0.000368649082793167 1 1 2.41673669787456 -3.77519917748877 0.513811101606942 -18.8215148123562 18.4350930598952 -1.02096120432945 0.308044046019168 -31.925120787497 38.8797542242148 -0.821124552469873 0.412186627930185 ERICH3 other 1 1 1 -1.02096120432945 -0.821124552469873 2.37172620299043e-06 66.8290940420612 20.9849708619493 3.18461695666388 0.00159257519188676 -138.387384262433 40.171400483749 -3.44492306954588 0.000647613375216979 RMI1 other 0.0238358483400538 1 1 3.18461695666388 -3.44492306954588 1.99513739175582e-08 57.6632206530122 14.5217351011472 3.97082168565773 8.8561748666529e-05 -124.314113516592 27.6596151564275 -4.49442672334884 9.77149729658677e-06 CTC1 other 0.000228483134103876 0.14388529769224 0.923521915094565 3.97082168565773 -4.49442672334884 0.0657710639153527 62.7171590251201 33.2186894175612 1.88800823045007 0.0599350519763029 -95.4978878795807 102.853519404459 -0.928484396377792 0.353860570451542 FBXO34 other 1 1 1 1.88800823045007 -0.928484396377792 0.000165927189504312 6.81994650748673 3.40535724126589 2.0027110297983 0.0460542190994744 -23.6083208974054 6.48619948701085 -3.63977718303037 0.000318215137157406 LINC00324 other 1 1 1 2.0027110297983 -3.63977718303037 0.00274253402884918 569.317926106774 255.572835493605 2.22761517282231 0.0266012132664791 -1202.22729634495 581.948040431162 -2.06586707544239 0.0396456389867343 SELENOW other 1 1 1 2.22761517282231 -2.06586707544239 0.00193838066928041 376.441747251655 210.924897468055 1.78471935637028 0.0752540623627504 -1560.04344107228 621.251649551804 -2.51112965607055 0.0125269843463079 EIF3K other 1 1 1 1.78471935637028 -2.51112965607055 5.97708976155148e-18 219.738760433179 45.3433464271993 4.84610814479648 1.96882499082878e-06 -332.935001163862 84.132649868289 -3.95726274740041 9.34893525141216e-05 MRFAP1L1 other 8.51795061918701e-14 1 0.0230805353674858 4.84610814479648 -3.95726274740041 0.000779274936869968 103.419639815942 33.5266552233813 3.0846989992553 0.00221756160671132 -51.974760192009 56.7130530176775 -0.916451459169522 0.36012901803314 SNX18 other 1 1 1 3.0846989992553 -0.916451459169522 1.22871888602727e-06 183.181569450152 48.3130102365595 3.79155777197949 0.00017901489491649 -330.075113293107 92.0220112048602 -3.58691479322584 0.000387073128038735 AURKB essential 0.0126508896505368 1 1 3.79155777197949 -3.58691479322584 0.128854185826465 -8.58561338276586 4.93657102484605 -1.73918562896269 0.0829667572012667 9.7513999593459 16.0340103104425 0.608169744845122 0.543507654223905 C14orf39 other 1 1 1 -1.73918562896269 0.608169744845122 6.50121963171385e-25 1175.49106900836 201.443572224019 5.83533669518696 1.31887135937998e-08 -1823.66289360905 373.76997653562 -4.87910481872333 1.68576563151292e-06 MRFAP1 other 9.68681725125363e-21 0.0251836527691716 0.000169765121379391 5.83533669518696 -4.87910481872333 3.63162667118221e-18 3.26177192590903 19.5734110053117 0.166642999782914 0.867763971230556 -216.4026483914 27.2555376760566 -7.93976809276101 4.16234858365074e-14 C3orf38 other 5.1859628864482e-14 6.38712390161206e-10 1 0.166642999782914 -7.93976809276101 0.537649464737189 -5.12931230218481 4.76818001040952 -1.07573797360563 0.282854840927867 -5.75291882191494 9.28849435224994 -0.619359672703188 0.536120148395924 KLHDC7A other 1 1 1 -1.07573797360563 -0.619359672703188 1.46872685145074e-06 32.2245364823264 9.08655330078038 3.54639822335702 0.000449072050704466 -65.431912681763 17.3071995630947 -3.78061814352034 0.000186711580448802 TMEM107 other 0.0150147946023809 1 1 3.54639822335702 -3.78061814352034 2.46249556596941e-17 204.559392270361 22.2354694408711 9.19968848934488 5.02059987079877e-18 -11.8479562742978 105.14516271006 -0.112681895856386 0.910354302521644 RRS1 essential 3.4856624736297e-13 1 7.37827357012587e-14 9.19968848934488 -0.112681895856386 0.0945810053984796 -7.06918567056204 4.5104212727476 -1.56730053427043 0.118038972032459 9.01000903212177 12.1111632676014 0.743942496112197 0.457460600290077 EXOC3L1 other 1 1 1 -1.56730053427043 0.743942496112197 0.0262388510428734 7.17981549302304 14.3215636951657 0.501329020059913 0.616506029684661 -60.6327284316907 27.5693677922847 -2.19927888403226 0.0286183891790493 TRIML2 other 1 1 1 0.501329020059913 -2.19927888403226 0.000189808417787275 469.160135049728 260.803655179127 1.79890168612666 0.0729763806692324 -1526.6288209895 504.500756109155 -3.02601889591459 0.00267895375333727 RCC2 other 1 1 1 1.79890168612666 -3.02601889591459 0.00123373550685306 7.21353985410255 3.47094088876364 2.07826640823953 0.0384840157321532 -13.0767779859903 7.26198478890407 -1.80071679659408 0.0726919602513088 IGSF22 other 1 1 1 2.07826640823953 -1.80071679659408 1.49836848288465e-06 91.8587084511613 18.4462571898015 4.97980200026421 1.07413510054278e-06 133.375900978165 35.5095057831133 3.75606187798854 0.000207208325861352 ZFP42 other 0.0153043356841838 1 0.0127875783719618 4.97980200026421 3.75606187798854 2.7745227801366e-07 174.63483816209 31.2668544121804 5.585302437525 5.01152647429465e-08 49.5048000825811 109.606486161352 0.451659402799436 0.651822253998094 DPM3 other 0.00298705122509506 1 0.000631502451025869 5.585302437525 0.451659402799436 3.26280318226482e-08 494.687758952714 84.3912498284961 5.86183709754319 1.14217667501158e-08 -302.19914741364 415.831569769999 -0.726734498731758 0.467921555574643 CYC1 essential 0.000369414576296023 1 0.000147260838709243 5.86183709754319 -0.726734498731758 0.941423514398219 -8.78337640733803 30.6459564793872 -0.286608003677282 0.774597960171484 -17.8549903780329 72.6347897302506 -0.24581871090069 0.805980161288707 TMTC2 other 1 1 1 -0.286608003677282 -0.24581871090069 7.27660069305376e-21 346.006500186494 41.1689629851593 8.40454738466994 1.49960306951424e-15 -584.098002318129 136.222845290747 -4.28781237883749 2.40203928890054e-05 FARSA essential 1.06238370118585e-16 0.350001144785698 2.17037552250795e-11 8.40454738466994 -4.28781237883749 6.82865859472581e-15 157.085891279615 34.8556381727598 4.50675699871075 9.2528633586766e-06 -322.645338642752 72.9257922650155 -4.42429665309969 1.32948367175065e-05 SPTY2D1 other 9.37574825055854e-11 0.19514161333956 0.10417798855534 4.50675699871075 -4.42429665309969 0.058475829721609 -3.13544230746582 2.2265797607119 -1.4081877338467 0.160049301432994 -10.5783924932994 4.43261942014808 -2.38648787333653 0.0175927752181294 C10orf67 other 1 1 1 -1.4081877338467 -2.38648787333653 3.04001082999636e-21 716.229251261309 73.3372493719221 9.76624099479145 6.98007098168532e-20 -268.812641946943 229.999274741341 -1.16875430259183 0.243375284185316 SAMD4B other 4.44875184861668e-17 1 1.03577273297229e-15 9.76624099479145 -1.16875430259183 0.00108000584492062 -38.4587908002262 11.1351619158636 -3.45381513900003 0.000627139072586968 -73.6784358350213 24.7754152735249 -2.9738527092926 0.00316432910459542 GIMAP7 other 1 1 1 -3.45381513900003 -2.9738527092926 0.555976085010706 45.7484391294445 42.8906859795513 1.06662875831027 0.286943569611543 -12.5224849296613 81.519422701528 -0.153613513377182 0.878011307139925 ALOXE3 other 1 1 1 1.06662875831027 -0.153613513377182 3.83878692359583e-13 153.26309784159 25.1793981015108 6.08684517492074 3.29192810122239e-09 -115.380631358752 49.4717023468591 -2.33225512536011 0.0203071893695879 EDC3 other 5.10059618538178e-09 1 4.31966805442402e-05 6.08684517492074 -2.33225512536011 7.10176098955737e-24 37.4215445590032 18.7916399258032 1.99139323160503 0.0472901923850573 -225.803254893928 26.9324020000403 -8.38407413098877 1.66341284779997e-15 TCAIM other 1.05333318997115e-19 2.55367140394251e-11 1 1.99139323160503 -8.38407413098877 0.149381261239505 -57.4278465060597 52.3584159845809 -1.09682169382228 0.273544042084499 -189.493846532792 101.812576981466 -1.86120273301093 0.0636323946340386 FUCA1 other 1 1 1 -1.09682169382228 -1.86120273301093 0.136310230742932 -1.16731442547702 1.67606420161281 -0.696461641716207 0.486646929512839 6.09978915929364 3.87982091763279 1.57218317257162 0.116899355217335 HNRNPCL1 other 1 1 1 -0.696461641716207 1.57218317257162 0.0612700442836745 -2.73703765644299 12.9954349282848 -0.210615317728672 0.833321506968483 -96.1314161624837 40.6739592824276 -2.36346345077882 0.0187023873350905 TMEM125 other 1 1 1 -0.210615317728672 -2.36346345077882 8.08524868000696e-05 409.466123904274 112.202764868015 3.64934076612043 0.000306914620629431 -510.097209496799 287.858639670867 -1.77204064495002 0.0773393236920495 ZNF664 other 0.703174077700205 1 1 3.64934076612043 -1.77204064495002 0.100002232236103 911.159337595784 606.796319028877 1.50159008718776 0.134201565244016 3654.07683145606 2012.90147265784 1.81532821208144 0.0704212869072771 CALR other 1 1 1 1.50159008718776 1.81532821208144 5.33889045141861e-07 135.212491659495 28.3500921854056 4.76938454997694 2.83352291755401e-06 -47.7551495284737 73.4682883710772 -0.650010373009776 0.516160780239179 LDLRAD3 other 0.00563359720433691 1 0.0329255363019776 4.76938454997694 -0.650010373009776 0.0532958364569793 20.2524953187942 10.4718642473994 1.93399139258549 0.0539957043277784 89.945858180573 48.1765772869105 1.86700391032161 0.0628152861565553 CDH4 other 1 1 1 1.93399139258549 1.86700391032161 1.53375976964009e-21 854.2309491018 93.6490860716826 9.1216154362461 9.00906683841774e-18 -1063.27041616766 310.63335505644 -3.42291128386542 0.000701414006450968 RAD23A other 2.24925870217719e-17 1 1.32144992385911e-13 9.1216154362461 -3.42291128386542 0.000708211330277306 405.064571856288 131.789395764095 3.07357484650252 0.00229999753157067 -724.290206586825 437.144492106694 -1.65686682473411 0.0985420447001886 GADD45GIP1 other 1 1 1 3.07357484650252 -1.65686682473411 2.7749546371757e-07 531.37806449144 100.23725781884 5.30120312600536 2.14837498782519e-07 -287.915170029849 268.389707825381 -1.07275041342931 0.284191431806297 PTPN11 essential 0.00298723866691964 1 0.00264013802253837 5.30120312600536 -1.07275041342931 0.960333077086106 -1.29281802044672 8.17679388669467 -0.158108182542109 0.874471590903501 1.81526763932531 15.6585892875931 0.115927917003585 0.90778261342164 NSUN7 other 1 1 1 -0.158108182542109 0.115927917003585 3.65109151804825e-12 159.426499952458 31.2071644738468 5.10865061406222 5.58718575532508e-07 -195.842474089569 61.3148712179497 -3.19404526502922 0.00154258838449645 CLK3 other 4.74824451922175e-08 1 0.00673982217664865 5.10865061406222 -3.19404526502922 0.264098676622211 210.53868116026 290.3544524863 0.725109187606462 0.468914942789128 1094.24722132473 670.485145222903 1.6320230643752 0.103658266909928 HLA-DQB1 other 1 1 1 0.725109187606462 1.6320230643752 0.0144178892220436 23.1929840296959 8.27032714588037 2.80436113597378 0.00534973290394865 45.0569584214854 33.2505099480875 1.35507571137498 0.176349219201391 GATA2 other 1 1 1 2.80436113597378 1.35507571137498 0.000174884331257429 37.2772178377866 13.8791424779561 2.68584445306999 0.00761209860303815 -53.7452600551484 27.2693097242025 -1.97090650987207 0.0495960751112465 ARID3B other 1 1 1 2.68584445306999 -1.97090650987207 3.41676360962993e-12 241.254846747628 32.9057301098603 7.33169712211718 1.91946081351989e-12 37.7624204996812 97.0286192670704 0.389188476399324 0.697398858658709 PACS2 other 4.44623448521142e-08 1 2.68436594770757e-08 7.33169712211718 0.389188476399324 8.09968333546597e-05 52.4275264635036 24.8965244665757 2.10581708036755 0.0360164414965521 -124.000143643234 44.0393215998572 -2.81566879639755 0.00517633480484522 ELMOD2 other 0.704267466018766 1 1 2.10581708036755 -2.81566879639755 0.0438517542424252 47.6948853014277 79.2750038546759 0.601638385144203 0.547840862444757 -222.289485710703 146.595810320136 -1.516342692368 0.130419920000423 EGR3 other 1 1 1 0.601638385144203 -1.516342692368 2.66339339134912e-12 477.261068477731 67.8079358491394 7.03842496458751 1.22088420237796e-11 -136.211628110755 154.251618180453 -0.883048292896392 0.37788358794325 VWA1 other 3.47333132165839e-08 1 1.68665152558515e-07 7.03842496458751 -0.883048292896392 0.356749793624561 23.9928447020059 21.0232919902259 1.14125060495571 0.254666811303611 -46.6367149456935 78.7810204653066 -0.591979066407641 0.554306053615806 LINC00174 other 1 1 1 1.14125060495571 -0.591979066407641 1.51114865393326e-15 271.53542594812 32.3717895047137 8.38802642988214 1.68220196851111e-15 -124.248187549767 61.607828553091 -2.01675972790853 0.044568791584252 GEMIN4 essential 2.09505649381306e-11 1 2.43313692725447e-11 8.38802642988214 -2.01675972790853 4.20496221357585e-11 232.783059720345 35.3378362123369 6.58736031039381 1.87802668580444e-10 -3.9797157724241 92.4814075130649 -0.0430326038437714 0.965702808164535 FJX1 other 5.32684613215789e-07 1 2.5381530658647e-06 6.58736031039381 -0.0430326038437714 4.41761791558804e-09 73.48455295779 12.883311992382 5.70385573222489 2.76918311393534e-08 -60.5407199333997 38.2861438722739 -1.58126971823982 0.114852802208651 KLHL28 other 5.21367266397701e-05 1 0.00035246162674169 5.70385573222489 -1.58126971823982 0.00900172324997381 17.8054200314043 6.12008138565964 2.90934366871744 0.00388124709975037 1.98454868899857 13.3448571632023 0.14871262125389 0.881876166124026 MKRN3 other 1 1 1 2.90934366871744 0.14871262125389 0.289276245614962 42.9771982328631 31.2048034291703 1.37726226445919 0.169402868821319 -83.0721105885706 102.353687749718 -0.811618148939629 0.417619770159899 ZBTB18 other 1 1 1 1.37726226445919 -0.811618148939629 5.11047606304756e-05 8.43060411369875 2.10496288508176 4.00510820093214 7.79322904603541e-05 -7.23897216136564 6.25544983399385 -1.15722647506932 0.248085328916363 C14orf28 other 0.45565004578132 1 0.816730404024511 4.00510820093214 -1.15722647506932 0.742863463900832 68.5942668866658 103.422217610131 0.663244982284605 0.507651157320485 -72.1693384579946 196.567606265594 -0.367147669084816 0.713751548554609 ALOX12B other 1 1 1 0.663244982284605 -0.367147669084816 6.71133348379337e-14 292.834970530452 36.8779816182678 7.94064527613395 3.46784024176922e-14 -179.198308006897 181.713495385339 -0.986158499823532 0.324802717947294 SHARPIN other 9.05224660294049e-10 1 4.96074546585087e-10 7.94064527613395 -0.986158499823532 0.00114193567432997 11.1781771381036 3.36802967073371 3.31890696665642 0.00100793073426902 -20.5488581608148 13.9368742893126 -1.47442372904035 0.141350642576494 LBX2 other 1 1 1 3.31890696665642 -1.47442372904035 0.122419420170834 5.24891985887414 11.3843132863869 0.461066006076156 0.645064462347283 -34.8569842837107 22.7109969651387 -1.5348064348393 0.125819469082355 DNHD1 other 1 1 1 0.461066006076156 -1.5348064348393 0.0504006878401693 10.3583092851184 4.35951316042302 2.37602431830101 0.0180886236195386 10.8465929036111 8.42223574807246 1.28785197043356 0.198728030051178 HTR1D other 1 1 1 2.37602431830101 1.28785197043356 5.56780775703283e-28 193.767409778377 26.9389736343711 7.19282822012013 4.57546223486415e-12 -361.310813159102 62.4345545769528 -5.78703276746811 1.71645258018653e-08 GCC1 other 8.37676677045589e-24 0.00026050600809491 6.36263778380209e-08 7.19282822012013 -5.78703276746811 6.50739194693615e-07 56.9470305204745 26.5843478794184 2.14212629095796 0.0329449259787044 -117.605611652567 37.831246762161 -3.10868981907826 0.00204956566343731 LSMEM2 other 0.00682495267394663 1 1 2.14212629095796 -3.10868981907826 0.0120488423198146 -53.2844689291029 59.8894302531267 -0.889714073149344 0.37428780418481 -580.844926804189 194.324972940608 -2.98903902063949 0.00301531357055921 CIITA other 1 1 1 -0.889714073149344 -2.98903902063949 2.79334073411692e-07 26.1529191058003 6.42490111420989 4.07055589508734 5.91526536959494e-05 -26.159157790248 16.3470968922151 -1.60023262617998 0.110533752606236 ZFPM1 other 0.00300619329805663 1 0.626604060601192 4.07055589508734 -1.60023262617998 0.142964117866538 99.1528930317312 78.7347215197725 1.25932868139797 0.208829429240792 -220.644780136852 149.645754043605 -1.47444731423893 0.141344299543878 ALOX15B other 1 1 1 1.25932868139797 -1.47444731423893 1.12132029234574e-07 57.5468074048027 10.3109874027335 5.58111509180457 5.09974374611631e-08 -23.2273541827267 21.9856901475183 -1.05647600902574 0.291547718705705 PLD6 other 0.00123378871766802 1 0.00064231272482335 5.58111509180457 -1.05647600902574 0.428508765195359 -172.756320319949 284.776080657258 -0.606639152843282 0.544521892685028 -823.662424781085 673.416771805258 -1.22310946098514 0.222191133629543 CDC42EP4 other 1 1 1 -0.606639152843282 -1.22310946098514 0.0292907150998794 30.9872913722094 13.8412192214486 2.23876891742245 0.0258849315450123 -31.0663372780037 40.8835117420281 -0.759874481283064 0.447910846044572 ZBTB42 other 1 1 1 2.23876891742245 -0.759874481283064 0.000564508099679728 30.8047485001223 15.4414331059753 1.99494103226739 0.0469051427498397 -64.3541609759213 28.6395008662554 -2.24704198849173 0.0253250238319219 LACC1 other 1 1 1 1.99494103226739 -2.24704198849173 1.10549946989436e-19 524.602715477836 52.4164281611496 10.0083644361457 1.09683752678558e-20 179.421311919892 258.278028211253 0.694682831375569 0.487759735571845 MAF1 other 1.60153708203597e-15 1 1.63308139363105e-16 10.0083644361457 0.694682831375569 0.941976456893079 -2.64380008187385 12.2414025525679 -0.215971990997001 0.829147181320771 -11.1990115690733 42.4726801123984 -0.263675650781551 0.792199572332482 FCER1A other 1 1 1 -0.215971990997001 -0.263675650781551 0.778803907763669 -5.5247651764291 9.53736463271742 -0.579275868039761 0.562819710286442 23.1750684061235 56.1227929851323 0.412935051401717 0.67993692658525 ARL14 other 1 1 1 -0.579275868039761 0.412935051401717 0.427050067785335 -3.27467953082146 2.51012771826341 -1.30458681723454 0.19297397160575 -1.10410727733295 12.3684665356882 -0.0892679196848803 0.928925006908664 WDR97 other 1 1 1 -1.30458681723454 -0.0892679196848803 0.531314877056752 5.69551224149942 13.1870648421548 0.431901435965697 0.666107596279487 -33.1813532391927 35.1930635623697 -0.942837874298388 0.346484092896131 PCED1B other 1 1 1 0.431901435965697 -0.942837874298388 0.156219937020152 -64.9506645290766 69.7609143537763 -0.931046634505024 0.352533506145224 -351.489544573264 188.8783454025 -1.86093087497267 0.0636737779618146 APOBEC3B other 1 1 1 -0.931046634505024 -1.86093087497267 2.99314778837147e-14 84.6541384711257 10.2449856192643 8.26298265484582 3.99600679701683e-15 58.9811802604725 32.4078369953047 1.81996657996699 0.0697130640029966 PIPOX other 4.05990566014706e-10 1 5.76463940537648e-11 8.26298265484582 1.81996657996699 0.00806137967425746 -3.42957588256541 1.19386085278879 -2.87267638816879 0.00435367440548325 -6.73502302034462 3.75329253843418 -1.79443061029141 0.0737282120173756 ATP8B5P other 1 1 1 -2.87267638816879 -1.79443061029141 0.654629129332664 1.90726471695061 2.81752606431655 0.67692886362464 0.49895917192505 12.2700393444093 17.4369641432949 0.703679794462818 0.482163825889818 FOXS1 other 1 1 1 0.67692886362464 0.703679794462818 0.456272575100855 9.70760770907079 31.0036585729189 0.313111682811208 0.754399787321098 101.562998356183 82.2007519099523 1.23554828874851 0.217532803467658 CDH5 other 1 1 1 0.313111682811208 1.23554828874851 0.724534685639227 -3.49986486486491 17.8187455471657 -0.196414773172493 0.844410603260022 20.7516568742655 33.0873287930647 0.627178368010633 0.530990949636316 FAM216B other 1 1 1 -0.196414773172493 0.627178368010633 6.18363874600566e-15 916.297986161191 107.542353991452 8.5203452607521 6.34443969892199e-16 46.9210365491605 462.409514987479 0.10147074190381 0.919240331766733 PCBP1-AS1 other 8.49322781763877e-11 1 9.20197533931646e-12 8.5203452607521 0.10147074190381 0.00714478585044496 734.836826758437 232.029187673852 3.16700167821709 0.00169005366980131 532.712353569432 566.89092316528 0.939708737255821 0.348082459888388 MYADM other 1 1 1 3.16700167821709 0.939708737255821 0.131916828357833 2.77687391246152 10.6435474556058 0.260897405122103 0.794339969892164 -37.2310667915942 22.2686822391032 -1.67190255767436 0.0955240780318553 MRGPRX3 other 1 1 1 0.260897405122103 -1.67190255767436 4.74566548903282e-11 168.725767861659 23.5727631762872 7.15765761526791 5.67707532149623e-12 76.5815278512733 116.153026946901 0.659315816937622 0.510168653737485 MROH1 other 5.99947031123529e-07 1 7.88318679142966e-08 7.15765761526791 0.659315816937622 0.248787062370574 144.71902670771 94.6920006310265 1.52831311772171 0.127425747795424 290.035373858425 388.73276264221 0.746104783880473 0.456153578536686 SERTAD2 other 1 1 1 1.52831311772171 0.746104783880473 0.0414831295204117 -8.25088553464872 3.3833066048638 -2.438704645564 0.0152885537882161 -14.2260082954601 11.3157365121162 -1.25718801248401 0.209611020242609 AKAP5 other 1 1 1 -2.438704645564 -1.25718801248401 0.0238397089002814 34.692252474983 14.3738531167789 2.4135666472399 0.0163585633176871 -24.2086128339311 34.4824502527351 -0.702056050440063 0.483154527558486 NKPD1 other 1 1 1 2.4135666472399 -0.702056050440063 0.712077749420041 1.11965355304969 5.55166790808682 0.201678769621423 0.840297216908461 -6.04662059559629 9.86422386414637 -0.612984932101352 0.540325823982377 GIPC3 other 1 1 1 0.201678769621423 -0.612984932101352 0.00155311844325037 266.513174631212 80.2278954973896 3.32195146063483 0.000997698128760039 -217.18295442431 248.192872750169 -0.875057176371565 0.382201159322478 CITED4 other 1 1 1 3.32195146063483 -0.875057176371565 0.167980513770535 -105.934294828472 62.7836964689016 -1.68728986642168 0.0925312939857989 -385.641149468788 361.598027664092 -1.0664912968691 0.287013177792339 ABCA13 other 1 1 1 -1.68728986642168 -1.0664912968691 1.02624197852514e-08 99.1377853623446 15.8836565265858 6.24149642095381 1.37914670442475e-09 41.9008660507391 78.1197240817857 0.53636730727405 0.592078550793943 TIGD5 other 0.000119033807089131 1 1.82847270072634e-05 6.24149642095381 0.53636730727405 0.366862967994192 2.73368049563867 2.12317139088364 1.28754584174241 0.198834504518385 5.23963940394217 5.51739248439884 0.949658632906386 0.343002393923873 ZNF154 other 1 1 1 1.28754584174241 0.949658632906386 1.47674911546952e-13 322.090978899918 42.3441791477986 7.60649953269109 3.16667796024979e-13 -162.34732591091 139.698969363425 -1.16212257435175 0.246051682640235 R3HDM2 other 1.97854846490606e-09 1 4.47198261546475e-09 7.60649953269109 -1.16212257435175 0.0513490140995786 90.6949708420863 53.2679657085684 1.70261750445442 0.0896168503080781 -140.539284572273 121.075925384904 -1.16075333825031 0.246612848584994 B3GNT3 other 1 1 1 1.70261750445442 -1.16075333825031 0.542650290529237 -6.42240328330195 7.68091993549669 -0.836150270701479 0.403696248377676 -25.0524537867271 30.1188426153332 -0.831786735854622 0.406151538802843 NRXN1 other 1 1 1 -0.836150270701479 -0.831786735854622 0.0121859501899453 154.77731107531 66.1593586080958 2.3394620856613 0.0199380458517121 -255.334559808997 227.736219917811 -1.12118555362492 0.263065602637535 SEPHS2 essential 1 1 1 2.3394620856613 -1.12118555362492 0.103754988033982 -2.17500561981845 1.02712460464696 -2.11756744019002 0.0349826712550206 -2.1995846367025 1.80209461471968 -1.22057111693031 0.223147089857463 GPBAR1 other 1 1 1 -2.11756744019002 -1.22057111693031 0.000385815382084751 19.6495022669319 8.63201665442588 2.27635129235496 0.0234852144919208 -61.5391403163786 23.4546980876748 -2.62374472211675 0.00911364497528142 ZNF784 other 1 1 1 2.27635129235496 -2.62374472211675 2.95156485535349e-23 362.216107309194 35.8509029752307 10.103402627249 5.17802058625004e-21 -215.132886431553 99.444846526322 -2.16333871433559 0.0312550970093706 C14orf119 other 4.36949661186531e-19 1 7.72094649615743e-17 10.103402627249 -2.16333871433559 0.699002427904728 2.05266077604301 2.91790985319246 0.703469565311351 0.482274684500635 -0.101069508026321 4.17973006665902 -0.0241808696768566 0.980723409025387 CCR8 other 1 1 1 0.703469565311351 -0.0241808696768566 0.051929602579457 26.8270451609275 13.1001699330485 2.04783947826887 0.0414020179290314 -27.6864245603706 30.6155194252789 -0.904326468409031 0.366511224966961 BBS10 other 1 1 1 2.04783947826887 -0.904326468409031 5.4729424042931e-07 47.9349183379332 13.0678107467666 3.6681674740196 0.000286027967629455 -107.569771614627 35.5075259933762 -3.02949215990701 0.00264920059556847 FIZ1 other 0.00577121776532707 1 1 3.6681674740196 -3.02949215990701 6.97902129987119e-18 966.691888138801 103.374806302847 9.35132961997312 1.57382266239005e-18 -192.289880817941 508.422687928921 -0.378208694032207 0.705527120823664 PUF60 essential 9.9416158416665e-14 1 2.32028675116164e-14 9.35132961997312 -0.378208694032207 0.0704589889557481 52.8633611861567 24.2376147470661 2.18104635038626 0.0299077110345534 85.3516822560787 65.8578358935777 1.2959988906104 0.195909821860947 SSC5D other 1 1 1 2.18104635038626 1.2959988906104 0.12238796241469 60.7043083699714 56.7310221572428 1.07003727522687 0.28542436275299 -269.531013300099 195.281647373514 -1.38021681466343 0.168501729963224 DCTPP1 other 1 1 1 1.07003727522687 -1.38021681466343 0.0253182867030537 30.2754844878233 13.6398517850478 2.21963441868274 0.0271577045697156 -41.7745573772303 46.9516082247187 -0.88973645327099 0.374288564865845 ZNF771 other 1 1 1 2.21963441868274 -0.88973645327099 4.41193241046537e-14 160.593358053209 38.7900896645661 4.14006153226058 4.45928983085555e-05 -170.818471014933 59.2398259092321 -2.88350730936757 0.00420254193393488 TSHZ1 other 5.96272665274394e-10 1 0.478035869867715 4.14006153226058 -2.88350730936757 0.0133134782497394 -4.0055206556736 4.42377004440752 -0.905454084517194 0.365906095335468 -25.8328619368231 8.80480104886334 -2.93395180577737 0.00358855779461986 PSTK other 1 1 1 -0.905454084517194 -2.93395180577737 3.83364759416128e-07 95.738533017003 17.4125237785243 5.4982571300251 7.90284414462754e-08 20.943554764729 52.1998682838653 0.401218536622295 0.688529551521034 SOCS4 other 0.00408973525345126 1 0.000987697461195549 5.4982571300251 0.401218536622295 6.66174557840757e-25 214.878062123884 38.7501979019875 5.54521199265572 6.20680199775034e-08 -255.684233987802 59.1789036197813 -4.32053009346959 2.08735432713771e-05 ZADH2 other 9.92533473726944e-21 0.30467023758902 0.000779139854777601 5.54521199265572 -4.32053009346959 0.524532431201296 13.8254448334655 12.4703523238468 1.10866513426629 0.26842310146276 3.09637459689339 42.9259134161049 0.0721329926489508 0.94254199367919 ZNF48 other 1 1 1 1.10866513426629 0.0721329926489508 0.546030238548295 0.533404742136051 6.44598378026646 0.0827499355131795 0.934102115456069 -17.496913365066 16.822166143118 -1.04011060265411 0.2990737365874 FAM71E2 other 1 1 1 0.0827499355131795 -1.04011060265411 0.224743142131797 3.93769832157322 2.50214347057396 1.57373003102415 0.116560101080788 -10.9595076058063 14.7479821814781 -0.743119124429801 0.45796695189006 C3orf80 other 1 1 1 1.57373003102415 -0.743119124429801 0.230631342888632 -1.08710553502729 2.00772100848322 -0.541462449430944 0.588565642450105 -8.97814161759956 5.23957514090068 -1.7135247374382 0.0875845047893627 TMEM150B other 1 1 1 -0.541462449430944 -1.7135247374382 1.39265217662045e-05 12.9622594414791 2.691417432944 4.81614605107925 2.29913227000298e-06 10.1124251381634 6.89098008497607 1.46748720986886 0.143263952245116 ANKRD18A other 0.131299247211776 1 0.0268584631781748 4.81614605107925 1.46748720986886 0.00136930230286063 10.0844071062322 6.54154539518194 1.54159399607006 0.124160559364393 -48.196189875584 17.0715545092405 -2.82318694817723 0.00505271088948867 TMEM86B other 1 1 1 1.54159399607006 -2.82318694817723 0.011254408412692 -52.1017072099083 17.270703642914 -3.01676806499341 0.00276369901724638 -53.8023154276177 59.4498623581985 -0.905003195860183 0.366157548912073 SEPT1 other 1 1 1 -3.01676806499341 -0.905003195860183 7.32208252524967e-05 25.1406553815198 20.4704601043338 1.22814315132063 0.22029860684052 -157.614661658851 41.0183811129077 -3.84253735477757 0.00014693686602918 TRNAU1AP other 0.640682220959346 1 1 1.22814315132063 -3.84253735477757 1.23223579442223e-29 514.88650369412 40.7450775485154 12.6367781011348 6.36257289702592e-30 -211.956578047944 237.33563968982 -0.89306679066387 0.372498868103666 EXOC3 essential 1.86079927315701e-25 1 9.66411197329266e-26 12.6367781011348 -0.89306679066387 0.672016480446038 -1.07234303366362 1.20969896013123 -0.886454456030363 0.3760404649627 -0.50911668731268 3.6678977632043 -0.138803401888692 0.889693088809898 TDRD6 other 1 1 1 -0.886454456030363 -0.138803401888692 0.00078214188580208 -0.783043620859278 3.10214173065996 -0.252420324036159 0.800879267397851 -19.1527386028206 5.44846189443841 -3.51525604361316 0.000503139072317875 CSNK1A1L other 1 1 1 -0.252420324036159 -3.51525604361316 0.8883560277851 51.7591568304689 147.738241479575 0.350343663983739 0.726313476344056 -47.7682017116156 298.751662887711 -0.159892672227802 0.873067453441452 ACTA2-AS1 other 1 1 1 0.350343663983739 -0.159892672227802 0.129403023935857 331.088645396457 289.718956138894 1.14279248347744 0.253979040526759 -2230.46113706017 1430.19689377372 -1.5595483018949 0.11985506630387 LYNX1 other 1 1 1 1.14279248347744 -1.5595483018949 0.024736774372477 58.079814745214 25.6905051407795 2.26075020428546 0.0244461410944793 1.48384557251589 46.9492623693439 0.0316053010767808 0.97480651903239 TH other 1 1 1 2.26075020428546 0.0316053010767808 0.0466954523666824 33.6343305798121 14.0217356209589 2.39872805257699 0.0170259037576609 -10.0325563935114 39.0900762801385 -0.256652259300115 0.797612674617184 FAR2P1 other 1 1 1 2.39872805257699 -0.256652259300115 1.75694215058955e-08 92.8941227432788 21.7782012241807 4.26546351496362 2.62979430842229e-05 -189.139459269437 62.1141866159281 -3.04502835139654 0.00251979104257082 FAHD1 other 0.000201749667152198 1 0.286700175504198 4.26546351496362 -3.04502835139654 3.8423490124789e-08 53.645621088373 33.251083693259 1.61334955525821 0.107719940443864 -220.596766663986 63.5841424348572 -3.4693676476016 0.000598148223493737 TDRP other 0.000433301698137246 1 1 1.61334955525821 -3.4693676476016 2.84599878692519e-05 164.388134956776 78.8598927223515 2.08455945451955 0.0379044242963109 -559.988450579601 158.018193910728 -3.54382262396927 0.000453312494558158 RCC1 essential 0.260750408858086 1 1 2.08455945451955 -3.54382262396927 0.1203271096565 523.938937815888 255.558430000181 2.05017278363902 0.0411776512198336 304.408280990503 879.692790873728 0.346039303889439 0.729544917358572 MYLPF other 1 1 1 2.05017278363902 0.346039303889439 1.59302307357956e-22 225.502062719192 21.386436461377 10.5441625642701 1.91412854943678e-22 -117.26737530728 80.8496579665139 -1.4504374941926 0.147937910874018 PRKRA other 2.34907182430043e-18 1 2.86659891563652e-18 10.5441625642701 -1.4504374941926 0.138489200054768 14.6187402995601 11.9982197868807 1.2184091106203 0.224000995785079 -27.4652771776514 26.9801278502137 -1.01798172826056 0.309485598511186 HERC2P3 other 1 1 1 1.2184091106203 -1.01798172826056 1.26487606829688e-08 84.8999657519888 15.4382208289303 5.49933614065757 7.85883326316996e-08 -109.694289775555 62.5352183650197 -1.75412020048073 0.0803761886796549 ZNRF2 other 0.000146067888366924 1 0.000982589922894141 5.49933614065757 -1.75412020048073 0.130676548875479 31.4072517964511 15.8926764107909 1.97620910315181 0.0489923186012084 38.0392750647701 51.821191789635 0.73404863437314 0.463458274403995 SLC9A4 other 1 1 1 1.97620910315181 0.73404863437314 0.744105495527999 3.97316512259148 5.65548887433252 0.702532568072711 0.482861031272508 8.25083998044357 18.3111848593365 0.450590174465779 0.652592007859482 ZNF816 other 1 1 1 0.702532568072711 0.450590174465779 0.000205664509990228 110.600794929851 59.4013444629173 1.86192410171618 0.0635303104311221 -486.756764726241 144.567072681355 -3.36699606416682 0.000852579040082511 FGD6 other 1 1 1 1.86192410171618 -3.36699606416682 0.000346369813550019 2.88588932818578 2.00573102949757 1.4388216992927 0.151181471810101 -14.0587623626537 3.9438371492299 -3.56474211045933 0.000419929610083185 ADGRD2 other 1 1 1 1.4388216992927 -3.56474211045933 3.35233174436388e-05 144.42660892627 43.0517714821972 3.35471930547604 0.000889965757293392 -148.70316797931 84.3110397563993 -1.76374491892117 0.0787291431809891 OAZ2 other 0.304592862292902 1 1 3.35471930547604 -1.76374491892117 0.00593749978761702 26.2445715762037 9.42454079796766 2.78470560410361 0.00567666999366887 -11.70882411295 21.8777521874764 -0.535193195928627 0.592887987421552 PNPLA1 other 1 1 1 2.78470560410361 -0.535193195928627 0.0767556407525982 38.8710326987182 17.8526138574982 2.17733005424257 0.0301862511895106 -11.8643392598277 42.6254986114047 -0.278339014118964 0.780931895669695 ALX1 other 1 1 1 2.17733005424257 -0.278339014118964 2.29121620291489e-10 91.0052063172565 13.3252428426584 6.82953454521066 4.29622858211897e-11 -12.8163045507744 32.481227685495 -0.394575743099074 0.693418863900349 CCDC43 other 2.83835863217097e-06 1 5.87337409461484e-07 6.82953454521066 -0.394575743099074 0.419218519682781 3.65967329875361 8.35966298085257 0.437777612223833 0.661842837462755 -24.5178139615373 20.3772734096683 -1.20319404213836 0.229790636371687 MEIOC other 1 1 1 0.437777612223833 -1.20319404213836 0.000763580870393951 43.3451444194413 11.9626377320131 3.62337683297436 0.000338081757678934 44.0652378788336 28.8328195781874 1.52830137750974 0.127425565934369 FZD2 other 1 1 1 3.62337683297436 1.52830137750974 2.04674173957969e-05 20.8549202972489 10.8957183997954 1.91404729197485 0.0565058808099805 -63.6708748050747 20.1137999277436 -3.16553187531967 0.00169690307699447 TIGD2 other 0.189835296346016 1 1 1.91404729197485 -3.16553187531967 0.35305004456704 -83.4348445955022 61.3154622584729 -1.36074721648164 0.174554183399912 -173.68971435568 240.254611186805 -0.722940190399223 0.470246335756445 HCLS1 other 1 1 1 -1.36074721648164 -0.722940190399223 0.0174396916965776 87.4151369137491 32.061627779177 2.72647220271587 0.00675768391220858 -42.7090520322256 129.87124076834 -0.328856887633872 0.742481009298448 MTURN other 1 1 1 2.72647220271587 -0.328856887633872 2.96637659632435e-07 267.357709842418 60.7197867056038 4.40313980578828 1.45641567683312e-05 -200.403795653079 118.911444864777 -1.68531965851541 0.0929017681255387 ZNF609 other 0.00318707501509088 1 0.16154562687433 4.40313980578828 -1.68531965851541 1.34375712265232e-30 901.385983896196 69.3697394956639 12.9939364116041 2.71850180675555e-31 772.600709494292 425.790643509803 1.81450842396565 0.0705357539648271 PAK2 other 2.03229827229937e-26 1 4.13511309825587e-27 12.9939364116041 1.81450842396565 4.33736949836491e-14 20.9772414770078 13.5009009586029 1.55376604430543 0.121228652744999 -116.297948857571 19.5092315078511 -5.9611752933871 6.6135660365246e-09 CCDC66 other 5.86238861399001e-10 0.000100598952981576 1 1.55376604430543 -5.9611752933871 0.52124098977966 -12.6214177858715 35.4530284053851 -0.356003939679083 0.722073673747166 56.4562925516437 66.2394351562149 0.852306370344202 0.394685505888743 ATP5EP2 other 1 1 1 -0.356003939679083 0.852306370344202 1.05422667414048e-07 380.433177480828 66.8315633963088 5.69241774616095 2.83371865552813e-08 -77.344391583965 243.285118422365 -0.317916657153226 0.750755518101698 MCFD2 other 0.00116186321757022 1 0.000360505687356288 5.69241774616095 -0.317916657153226 3.01041552206123e-18 42.5734948754064 7.16074209823636 5.94540262606189 7.33781102062580e-09 -68.3942329466489 17.5302811448489 -3.90149093340388 0.000116987514820288 HARBI1 other 4.30218482257771e-14 1 9.52227736146609e-05 5.94540262606189 -3.90149093340388 2.14518164772908e-07 22.1492103179027 8.10314857398623 2.73340789887637 0.00661691650258435 -30.3309700245149 14.8321430206196 -2.04494859457254 0.041677662415157 C11orf71 other 0.00232473335164401 1 1 2.73340789887637 -2.04494859457254 0.000396738398910392 39.1594767990397 21.7295242259978 1.80213226906221 0.07246850405878 -80.8493918860963 34.9740066061347 -2.31169945144102 0.0214310112170089 TPRXL other 1 1 1 1.80213226906221 -2.31169945144102 0.414981639570299 81.5057366608059 62.5479615525366 1.30309181366919 0.193483206695622 -2.6754046529379 120.840779369714 -0.0221399155723124 0.982350188310996 GAS1 other 1 1 1 1.30309181366919 -0.0221399155723124 0.0012182026461509 -54.1812251300889 67.0105460702142 -0.808547733267498 0.419379813949773 -387.058996138542 109.962355701232 -3.51992273783388 0.000494697539208748 ARHGAP45 other 1 1 1 -0.808547733267498 -3.51992273783388 0.0372024870958038 7.26399203422 3.03723636682353 2.39164528436652 0.0173501084649685 -2.38878657086694 8.87914043496192 -0.269033538591305 0.788077249393594 ZNF571 other 1 1 1 2.39164528436652 -0.269033538591305 0.0259355937676453 18.0711236129827 14.8654422088039 1.2156465552219 0.225015653940768 -60.9581757429129 31.6424829759053 -1.92646625706745 0.054931614714483 MIGA1 other 1 1 1 1.2156465552219 -1.92646625706745 0.0381454962734672 423.116936837434 167.118999199772 2.5318302458935 0.0119529645934701 156.12819846452 305.104859722096 0.511719802191054 0.609293470549085 NRIP1 other 1 1 1 2.5318302458935 0.511719802191054 0.197051935645445 1.11067767480906 4.92437220501905 0.225547060329239 0.821698601776901 20.1005274502292 11.6354711614591 1.7275215735835 0.0850449519162346 RNF182 other 1 1 1 0.225547060329239 1.7275215735835 0.234667840883254 33.2430314454656 28.6002997064534 1.16233157647521 0.245966933021897 198.925532156053 148.289045835657 1.34147152296411 0.180718638804376 TSPYL5 other 1 1 1 1.16233157647521 1.34147152296411 0.000803781280850212 -5.87057919015889 3.36448543230799 -1.74486687734943 0.0819710393659935 -25.4271585667024 7.0790184902677 -3.5919045276771 0.000380019543770329 FUT7 other 1 1 1 -1.74486687734943 -3.5919045276771 0.000420809622052537 252.213723556087 74.8842999308943 3.36804542192205 0.000849452247753628 -103.592523840691 163.326135805503 -0.634267891845886 0.526359159704408 HIST1H2AC other 1 1 1 3.36804542192205 -0.634267891845886 0.000788365634527479 1.24549466085 2.56251475675891 0.486043897918976 0.627268702969301 -15.1751592543175 5.09918090644025 -2.97599938749994 0.00314286334124291 SKIDA1 other 1 1 1 0.486043897918976 -2.97599938749994 2.58549695024832e-05 56.1525519324389 14.2622137181964 3.93715541233243 0.00010121504072805 -23.4617606117162 31.1065504621783 -0.754238585221553 0.451260629632495 HIST1H2BC other 0.237684734636328 1 1 3.93715541233243 -0.754238585221553 0.000146718633111572 41.9882701844228 10.2916339749232 4.07984488048566 5.69909559430243e-05 -76.2013787962272 61.7845615401457 -1.23334012408122 0.218356908111008 MB21D2 other 1 1 0.604446078731716 4.07984488048566 -1.23334012408122 0.592925349913114 -24.9407499403431 24.3992412819693 -1.02219366791434 0.307463801812946 -5.37740650567951 57.9277028474757 -0.0928296176328323 0.926097193041648 SSTR2 other 1 1 1 -1.02219366791434 -0.0928296176328323 0.000120538240255572 26.097432862475 6.1046035269724 4.27504140885921 2.52511037519223e-05 -6.29890300489204 13.626615583817 -0.462249996424103 0.6442161817021 ZNF594 other 1 1 0.275540044140976 4.27504140885921 -0.462249996424103 0.0331127947843217 -9.1092215329075 50.9298762129502 -0.178858112570697 0.858162654550753 -237.603806519519 98.5884731176032 -2.41005666287264 0.016515661811458 PCGF5 other 1 1 1 -0.178858112570697 -2.41005666287264 0.205927142913311 38.99815722624 23.9135789935819 1.63079550897449 0.103917265213751 -26.9172438043782 43.7487662249537 -0.615268637885039 0.538814627274322 SLC47A2 other 1 1 1 1.63079550897449 -0.615268637885039 0.0154198536385464 -79.4246658527222 39.0622459405534 -2.03328467015425 0.0428486921774695 -240.693402942268 90.1120349793876 -2.67104613714833 0.00794814458733947 PRF1 other 1 1 1 -2.03328467015425 -2.67104613714833 0.880809365181033 0.410499914926847 2.37992947459168 0.172484066989958 0.863166365784336 2.83828332923723 5.66141109263847 0.501338497203965 0.61647870146693 OR2A4 other 1 1 1 0.172484066989958 0.501338497203965 0.87015264469187 1.21344257683384 3.15306911619217 0.384844902575198 0.700610396847944 2.74376900123582 5.52416890487117 0.496684487474013 0.619755818620535 MAB21L1 other 1 1 1 0.384844902575198 0.496684487474013 0.310399842846634 45.9172074589866 29.9643909437308 1.53239248363877 0.126413614017885 3.7729909104787 101.760029129017 0.0370773371703255 0.970446460769914 YOD1 other 1 1 1 1.53239248363877 0.0370773371703255 7.50238768112197e-06 108.225502552471 22.0993134562214 4.89723369763792 1.5452729265964e-06 -27.6317022000313 111.819354510336 -0.247110192336847 0.80498140760382 TMEM64 other 0.0724430554489137 1 0.0182404016255439 4.89723369763792 -0.247110192336847 0.084928009805336 -23.6791522432921 117.143397361383 -0.202138172331154 0.839937555673206 -464.381428551757 219.27290538909 -2.11782403178238 0.0349631776632445 SHISA2 other 1 1 1 -0.202138172331154 -2.11782403178238 0.597814064972539 19.1437440850667 37.629355451561 0.5087449374388 0.611282691945337 -54.8479600011562 82.2073812533029 -0.667190210477025 0.505132967107166 S1PR5 other 1 1 1 0.5087449374388 -0.667190210477025 0.00063041883449116 41.5447837513347 12.6753025691501 3.27761672943799 0.00116192301244291 -41.6123548597776 38.6258593692385 -1.07731855133604 0.28214944742935 SMG1P3 other 1 1 1 3.27761672943799 -1.07731855133604 1.27897083005393e-06 265.914246224447 71.3943422183658 3.72458430124792 0.000231165496470258 -411.947564184756 161.081266768811 -2.55738964839404 0.01100684355941 GPR157 other 0.0131388673371441 1 1 3.72458430124792 -2.55738964839404 0.861955388365592 -19.5770604353383 37.4756911368939 -0.522393579449296 0.601760046714683 -26.4905565048961 69.3541284518819 -0.38196077286553 0.702745580339052 PIPSL other 1 1 1 -0.522393579449296 -0.38196077286553 0.523514344740197 -1.51731043667595 1.94812096848476 -0.778858428825445 0.436640484898949 -3.88497486250295 3.58869747742397 -1.08255847335776 0.279822062274845 WDFY3-AS2 other 1 1 1 -0.778858428825445 -1.08255847335776 0.00191943929868339 30.9590718997759 17.1894746990823 1.80104816707567 0.0726515916800881 -62.146323107829 41.7015224258333 -1.49026509088144 0.137155161900876 SLC36A4 other 1 1 1 1.80104816707567 -1.49026509088144 1.42128248043955e-08 289.248463054847 94.6221295469631 3.05687965848715 0.00243187124296627 -503.376593327652 153.148891942567 -3.28684450107825 0.00112986043609548 ZDHHC20 other 0.000163731741746636 1 1 3.05687965848715 -3.28684450107825 0.138200309822223 -1.31813209603436 1.51117183375271 -0.872258247932687 0.383721503787747 3.37002464296171 3.00460770196587 1.12161885252333 0.262865475440663 OR51E1 other 1 1 1 -0.872258247932687 1.12161885252333 0.00241329217570908 23.2805268458991 9.86262099548784 2.36048073392964 0.0188507942244488 -56.1022423626976 22.0152126768909 -2.54833978604202 0.0112905808635177 ZFP3 other 1 1 1 2.36048073392964 -2.54833978604202 0.00337027878209489 142.12939286398 48.8713720747386 2.90823414261058 0.00388970353388151 -57.7270526734308 88.2330009040343 -0.654256934275839 0.513417681639331 ARSJ other 1 1 1 2.90823414261058 -0.654256934275839 0.0322907341060977 6.82933651007406 5.77150457141907 1.18328529858461 0.237574418786867 40.8055442936842 16.0734488972951 2.5386925080249 0.0116002172091313 HOXC9 other 1 1 1 1.18328529858461 2.5386925080249 5.95068625376929e-09 427.577354684046 119.881710187117 3.56666045234643 0.000416805483194952 -854.417234870309 249.429927422536 -3.4254800283966 0.000693733319198165 PPA1 essential 6.98253525017288e-05 1 1 3.56666045234643 -3.4254800283966 0.572288475634403 11.3256849847207 20.6714541094516 0.54789009639831 0.584149334785953 57.2012354520933 57.5693144048497 0.993606334267454 0.32116528298475 HOXC10 other 1 1 1 0.54789009639831 0.993606334267454 5.06024316654157e-09 214.384092464863 44.8977019844266 4.77494577649486 2.74728445909502e-06 -191.420282340752 99.6081221982939 -1.92173367107236 0.0555327335715024 PSMG4 essential 5.95641223133608e-05 1 0.0319619073971115 4.77494577649486 -1.92173367107236 0.474118543490601 -1.13948601676552 1.04222749584891 -1.09331793807396 0.275094954704931 -3.39575881293192 4.91337669754378 -0.691125273303281 0.489999070260592 BHLHE22 other 1 1 1 -1.09331793807396 -0.691125273303281 2.03526040938918e-21 27.5149532559551 2.78423177672784 9.8824219613972 2.97887111069806e-20 56.332141301952 18.4570041123031 3.05207394218447 0.00246488249538414 MAP6D1 other 2.98124944767328e-17 1 4.42958134160801e-16 9.8824219613972 3.05207394218447 0.0050531331473939 8.10760639386267 5.29569435211694 1.53098080341847 0.12679723503812 -26.7297807849291 11.3976224511835 -2.34520672178902 0.0196489399595536 ZNF443 other 1 1 1 1.53098080341847 -2.34520672178902 0.0697241019830327 -8.33957548073852 9.36426442997081 -0.890574539314298 0.373826537484982 -82.6857992829787 36.2218430302283 -2.28276068707975 0.0231000838501672 LINC01559 other 1 1 1 -0.890574539314298 -2.28276068707975 0.213333748244582 2.56412632233496 14.9845269590275 0.17111826948866 0.864238921227249 -38.9261723612295 26.2904181389627 -1.48062203330043 0.13969121106178 CXCR2 other 1 1 1 0.17111826948866 -1.48062203330043 0.0840634163540577 9.66922822505993 4.48804545697524 2.15444079561008 0.0319587607935051 -9.6641913352932 14.4572128814517 -0.668468494898638 0.504321039568388 GREM2 other 1 1 1 2.15444079561008 -0.668468494898638 0.128653415822684 -2.1743608568736 3.31984633945969 -0.654958282565416 0.512972590834128 -15.6265814593489 7.75590238120814 -2.01479862578089 0.0447751425239687 CAPS2 other 1 1 1 -0.654958282565416 -2.01479862578089 0.371415133077701 5.30840632080551 3.78898709229232 1.40100934405505 0.162183323965003 2.55825565654151 12.805152629438 0.199783300564517 0.84177735476294 ZNF792 other 1 1 1 1.40100934405505 0.199783300564517 0.696307883767913 29.6486171440856 43.8324112638953 0.67640853626748 0.499274520691695 61.6224658733431 102.83362268898 0.59924433528633 0.549437981623805 CUEDC1 other 1 1 1 0.67640853626748 0.59924433528633 7.31399422433519e-14 186.015135187939 23.2503946845861 8.00051516163112 2.29660527307214e-14 -14.9369199571116 57.6642400265859 -0.259032633573685 0.795776609708242 KCTD2 other 9.85707001613653e-10 1 3.28988705367584e-10 8.00051516163112 -0.259032633573685 0.0214578490602016 17.0590489916045 26.8917238972959 0.634360558540463 0.526303060544105 -104.189549946972 48.7084628348711 -2.13904409794638 0.0331958098713148 D2HGDH other 1 1 1 0.634360558540463 -2.13904409794638 0.0180630985960608 14.0745679425615 9.58570899214705 1.4682865872615 0.143014827957665 -24.8090405727838 16.1082381823688 -1.54014612224561 0.124519191717522 OXTR other 1 1 1 1.4682865872615 -1.54014612224561 9.26831394676018e-12 116.693957585593 21.337072201402 5.46907075554279 9.1501658394103e-08 -139.802809508203 58.6541202064077 -2.38351217299361 0.0177330736001572 CMTR2 other 1.19255395552963e-07 1 0.00114148318846644 5.46907075554279 -2.38351217299361 1.53424776124328e-14 1374.821600957 165.813525956064 8.29137184695828 3.16554879100819e-15 -249.687886523099 815.511647147163 -0.306173293044387 0.759672430532576 FAM83H other 2.09225367200746e-10 1 4.56883657006212e-11 8.29137184695828 -0.306173293044387 0.000686833864766439 5.95810729355034 1.54842698774243 3.84784516203577 0.000144179858543909 -0.550173221059292 9.09714784066715 -0.0604775508428964 0.951813525061471 ZNF572 other 1 1 1 3.84784516203577 -0.0604775508428964 0.761178727024979 -2.05627287085353 6.48150423632839 -0.317252414852752 0.7512596216162 -9.34528960414702 12.68149245026 -0.736923484424378 0.461710510237983 ST20 other 1 1 1 -0.317252414852752 -0.736923484424378 1.28408084301891e-14 441.303765323793 58.2270664055154 7.57901423799004 3.86787919586101e-13 -310.331712110131 167.871576313565 -1.84862571094505 0.0654429475045715 PITPNB other 1.75431124773244e-10 1 5.45757754535988e-09 7.57901423799004 -1.84862571094505 0.000382470466595745 44.5501667511799 21.2031697684408 2.1011088076788 0.0364157106664244 -100.146007583905 42.900179840156 -2.33439598521601 0.0201953137543199 LRRC57 other 1 1 1 2.1011088076788 -2.33439598521601 9.39947824099306e-06 235.024002642812 62.0370853650272 3.78844365849761 0.000181273508177924 -318.267061294564 172.499805801294 -1.84502851940124 0.0659630768837701 MRPL14 essential 0.0899060093750986 1 1 3.78844365849761 -1.84502851940124 0.0201204111496158 -8.6536479251947 3.07783422046885 -2.81160299916234 0.00523755485013147 -5.18207151221082 9.38714702093887 -0.552039027475733 0.58131181720008 GPR137C other 1 1 1 -2.81160299916234 -0.552039027475733 0.205712803894992 3.49201786970555 5.80351990042202 0.601706882998992 0.54779664951936 -14.2554069723476 10.4714268707493 -1.36136241491295 0.174359977569786 BBS12 other 1 1 1 0.601706882998992 -1.36136241491295 0.712416274363829 0.744075081565066 3.91756163009792 0.189933216582599 0.849482644429938 -7.87492236874548 11.045752520995 -0.712936701576226 0.476407745886088 ZFP82 other 1 1 1 0.189933216582599 -0.712936701576226 0.348540578628672 3.48557476530792 2.48263729639837 1.40398066619096 0.161316027580494 5.78132937714855 6.98775885914216 0.827351013921263 0.40866845441979 LSMEM1 other 1 1 1 1.40398066619096 0.827351013921263 0.00224980205793804 800.08857254193 339.091367108642 2.35950734860669 0.0188994490485982 -1362.78527190269 924.951104706973 -1.47335925647056 0.141637152016999 NQO1 other 1 1 1 2.35950734860669 -1.47335925647056 2.52431257160196e-10 187.442608541565 29.5835258864359 6.33604693575447 7.99479385250891e-10 -46.0986458321612 60.0802167819347 -0.767284945050705 0.443477860212984 AEN other 3.12131249478582e-06 1 1.06706513549436e-05 6.33604693575447 -0.767284945050705 0.000123774260004588 56.7238662128119 14.0307998260477 4.04281059640706 6.62228122044001e-05 -14.1548865508761 31.7756687299847 -0.445463057635638 0.656286358903446 FKRP other 1 1 0.699114228441852 4.04281059640706 -0.445463057635638 9.87530169067202e-05 92.6234148820439 52.4395246246987 1.76629013220343 0.078300577778905 -272.745737948339 97.3660838961438 -2.80123968259076 0.00540048486896444 TRAPPC5 other 0.851942276854275 1 1 1.76629013220343 -2.80123968259076 0.000396561326717639 77.8264433840652 20.0698507472937 3.87777888156739 0.000128335435567586 45.6652747211548 38.1956000222154 1.19556374803891 0.232766096231431 RPH3AL other 1 1 1 3.87777888156739 1.19556374803891 0.000178198732048291 39.4762206669614 16.9222897437252 2.33279427694465 0.0202804228977797 -105.585152444451 39.8672077541993 -2.64842105560628 0.0084890384901392 SLC25A42 other 1 1 1 2.33279427694465 -2.64842105560628 2.1466528740956e-10 81.3502372248577 11.7967213735744 6.89600395302112 2.87722475942017e-11 22.3934505874542 28.4509802424809 0.787088894533689 0.43181420104828 METTL23 other 2.66227889445337e-06 1 3.9484155373523e-07 6.89600395302112 0.787088894533689 0.0912642696854706 23.9021028331465 10.9423302921568 2.1843704398394 0.0296604507566248 18.2656246424239 25.2261661530538 0.724074539571392 0.469548989551935 SLC26A11 other 1 1 1 2.1843704398394 0.724074539571392 1.21989651388407e-10 125.583586474014 101.894832502381 1.23248238786868 0.218673688518876 -760.926415221532 145.315361524804 -5.2363797415296 2.97294768341662e-07 HIGD1A other 1.52072299420788e-06 0.00448052945367718 1 1.23248238786868 -5.2363797415296 0.0424522614092403 15.0099631088916 6.01938008486007 2.4936061350644 0.0131514987967441 -3.24085460218676 29.6047897148618 -0.109470617200832 0.912898057063287 MAPK15 other 1 1 1 2.4936061350644 -0.109470617200832 1.07549194935701e-08 215.198719128367 50.0426721852746 4.30030431491807 2.28171491398189e-05 -420.496134049957 105.260047535046 -3.99483131441638 8.07598450368985e-05 EHMT1 other 0.000124563477574529 1 0.249688063037039 4.30030431491807 -3.99483131441638 0.740517979036762 18.4326772749592 29.5309906640753 0.624180796527855 0.532954975723773 -91.5491922738582 183.56740535879 -0.498722483411049 0.618318614710106 ADIPOQ other 1 1 1 0.624180796527855 -0.498722483411049 0.143705068265481 -13.1395243305063 93.3628429676878 -0.140736120632635 0.888166957161277 225.159162791855 128.424888973449 1.75323618802899 0.0805189596689576 F2R other 1 1 1 -0.140736120632635 1.75323618802899 0.16495370293564 -215.264607318796 143.481417279129 -1.50029607597212 0.134529894076505 -494.410948570737 299.013136493394 -1.65347567792113 0.0992208881001058 MUC16 other 1 1 1 -1.50029607597212 -1.65347567792113 1.64302727605607e-18 2109.66927460331 300.162573244636 7.02842213737254 1.26564636212417e-11 -1689.72383976228 453.711509232049 -3.72422520782491 0.000231480967093007 NPM1 essential 2.35347227022272e-14 1 1.74785762609348e-07 7.02842213737254 -3.72422520782491 5.93340332285046e-13 207.961787590968 45.2737248536912 4.59343224492854 6.29216162291807e-06 -294.925696844927 92.6716036460612 -3.18248185249206 0.0016044600035551 DHTKD1 other 7.8522659574603e-09 1 0.0716299679152993 4.59343224492854 -3.18248185249206 0.0354064058489654 -44.966617641676 18.8947066331411 -2.37985264946136 0.0179221589146224 59.0632706301509 87.2943221461084 0.676599224074323 0.499163168885669 PENK other 1 1 1 -2.37985264946136 0.676599224074323 0.00125250700572963 73.3054162383043 20.0730043716689 3.65194043108803 0.000303947468025167 29.1280918183071 67.5492221214677 0.431212838630898 0.666603961833095 HIST3H2A other 1 1 1 3.65194043108803 0.431212838630898 1.56789145778568e-17 126.687762730926 20.0001728315296 6.33433339791981 8.16077206062871e-10 -120.433428334038 44.7707168920156 -2.69000446484957 0.0075235521029823 ZNF746 other 2.22515155688944e-13 1 1.08881020832908e-05 6.33433339791981 -2.69000446484957 0.000147316620033239 1177.25214695647 294.618170957686 3.99585722472477 8.00514987962479e-05 -727.949906844387 562.366560869487 -1.29444024146615 0.196446705851198 POLR2A essential 1 1 0.838219243895511 3.99585722472477 -1.29444024146615 0.00757577928186087 14.7069813932032 5.48919334644264 2.67926095238279 0.00776119589098506 4.16461633092416 10.3422871801131 0.402678465449324 0.687454492538169 TMEM136 other 1 1 1 2.67926095238279 0.402678465449324 0.0366749856619815 -48.6374343823888 36.4514399102966 -1.33430762960478 0.183051774604837 -172.209925878155 66.7601250201713 -2.57953270498105 0.0103392642221017 FRAT2 other 1 1 1 -1.33430762960478 -2.57953270498105 6.80467485418601e-12 81.1165027668647 13.8764178923516 5.84563706542555 1.24393612623576e-08 -116.10511749214 26.4872780315725 -4.38342956017391 1.58645514010075e-05 TMEM102 other 8.79095944412291e-08 0.232336355267755 0.000160243851781691 5.84563706542555 -4.38342956017391 0.0749193425602258 64.317891457956 31.3432263518881 2.05205076005462 0.0409780422258362 -9.55272204794258 68.7048868262251 -0.139039921164621 0.889506063951083 ZNF322 other 1 1 1 2.05205076005462 -0.139039921164621 5.21406932578158e-05 1426.1409973502 403.896192197278 3.53095925364311 0.000476280386973766 -174.451086216054 954.29264677407 -0.182806696463371 0.855068044330439 HEPHL1 other 0.464417154847365 1 1 3.53095925364311 -0.182806696463371 5.02362495721377e-05 666.109095740643 161.997689560709 4.11184318459689 4.99468325846395e-05 -517.753114526502 346.48390367028 -1.49430639935068 0.136080958440441 LRRC75A other 0.448207818682612 1 0.532982650510688 4.11184318459689 -1.49430639935068 0.983066212808592 0.874014687436811 9.22080248132093 0.0947872692433602 0.924543875288804 3.85032603717777 22.6971012189906 0.16963955000369 0.865402163608211 CCL13 other 1 1 1 0.0947872692433602 0.16963955000369 0.00795270552481771 157.962609287208 78.1694051249256 2.02077282070603 0.0441410464290131 -177.62719834211 132.460324810032 -1.34098416712215 0.180882630767232 DDX60L other 1 1 1 2.02077282070603 -1.34098416712215 0.0447661029186592 5.83862241925598 4.85675624697588 1.20216500939109 0.230191223614542 -43.2875226744725 22.4764584463431 -1.92590495419065 0.0550047451725959 SYNE4 other 1 1 1 1.20216500939109 -1.92590495419065 1.18962787203509e-06 117.799701346609 26.0209562070258 4.52710885831331 8.47188422042684e-06 -101.350357713229 58.2826443914107 -1.7389457663003 0.0830150987506652 OGFOD3 other 0.0122531670819614 1 0.0956306290801782 4.52710885831331 -1.7389457663003 0.0919801789386259 5.2072335726118 8.91570699466177 0.584051671474804 0.559611666939392 -52.9223730438526 27.1898117861991 -1.94640453784659 0.05251228168318 WASHC1 other 1 1 1 0.584051671474804 -1.94640453784659 0.000769129656012158 14.4140149733568 3.78072742403653 3.81249779651332 0.000165482866864501 10.4885375800267 8.67698325060476 1.20877697664055 0.227655102545256 AATK other 1 1 1 3.81249779651332 1.20877697664055 0.229168335000635 65.3028791978384 41.1208249491506 1.588073178945 0.113263535903789 -30.2328101377527 105.391030549758 -0.286863217676565 0.774403873941988 DDN other 1 1 1 1.588073178945 -0.286863217676565 0.0121509084429402 8.20892733454554 6.62602034530763 1.23889256397453 0.216310574739945 -25.2631958961918 14.8377030979936 -1.70263522118918 0.089625975123913 ZNF467 other 1 1 1 1.23889256397453 -1.70263522118918 0.00082801762432956 411.042114525379 115.462721759241 3.55995518088055 0.000428684110042219 838.955402949068 763.039324479808 1.09949169857139 0.272401304489662 SOX2 og 1 1 1 3.55995518088055 1.09949169857139 0.115329404960513 12.4961638809016 6.41701212720225 1.94734926990855 0.0523673037802022 15.1675250442026 22.0528831903372 0.687779684556099 0.492089750261573 ZNF678 other 1 1 1 1.94734926990855 0.687779684556099 0.00806291835458554 706.249533135959 256.958217725442 2.74849950076545 0.00632991205483723 -758.534083352312 1049.38713601661 -0.722835317223006 0.470314022027653 TMEM45A other 1 1 1 2.74849950076545 -0.722835317223006 3.28493105227462e-13 561.963503858853 70.9118188867993 7.92482145685684 3.91887999554607e-14 -105.079509752951 437.565748402292 -0.240145646995072 0.810372566670734 RAP2B other 4.36895829952525e-09 1 5.60203895363311e-10 7.92482145685684 -0.240145646995072 0.0155815690282607 35.6541475212012 15.4095544634773 2.31376887668662 0.0213136702659001 -39.3491875868953 33.9588722535451 -1.1587306932075 0.247429954321327 ZBTB2 other 1 1 1 2.31376887668662 -1.1587306932075 0.0111190537763055 37.650443424727 17.235550324093 2.18446424493314 0.029667402546413 -74.3229012302994 41.9043738043276 -1.77363111491297 0.0770933477232525 RNF135 other 1 1 1 2.18446424493314 -1.77363111491297 0.697119627006721 4.88473964655132 7.35601141815655 0.664047317068393 0.507139692298837 -8.43864915161718 17.8637560613316 -0.472389408064284 0.636971866572988 ACBD4 other 1 1 1 0.664047317068393 -0.472389408064284 0.000147183100497712 88.8351570903036 24.0593047319186 3.6923409915686 0.000261167977382506 -67.677123143465 55.46570085984 -1.22016168721068 0.223302016451345 SGSH other 1 1 1 3.6923409915686 -1.22016168721068 0.028133298136883 6.22574363940707 3.44388313192566 1.80776855686329 0.0715902621392965 -6.50458950649249 5.93800458400785 -1.09541672029196 0.274165658739886 MAB21L2 other 1 1 1 1.80776855686329 -1.09541672029196 2.27281813658407e-12 310.250258434065 80.4104790450745 3.85833117920058 0.000138077601733949 -410.340429904493 115.63983736993 -3.54843485806556 0.000445555199323295 SETD2 other 2.96920961363342e-08 1 1 3.85833117920058 -3.54843485806556 0.85985550817033 1.53699255893308 10.0126579964457 0.153504949382939 0.878097451699458 15.3006416791715 27.8411139043509 0.549570025529057 0.583000058219638 C6orf223 other 1 1 1 0.153504949382939 0.549570025529057 0.00337783648930648 2.21594971981191 3.53231603464374 0.627336200407504 0.530886237668848 -12.670457828363 5.05583644856616 -2.50610516326263 0.0127028525889717 TMIE other 1 1 1 0.627336200407504 -2.50610516326263 5.47566724106734e-10 110.846507110952 37.3853343484604 2.96497300459522 0.0032560134651636 -230.774176707854 61.7442638373622 -3.73758082719596 0.000220244457296625 MEX3D other 6.69126536858429e-06 1 1 2.96497300459522 -3.73758082719596 0.000760422873183991 138.31823259559 36.0865826750507 3.83295458705818 0.000152780112287143 35.9328375379956 85.210190218524 0.421696483083124 0.673533293351931 MRPS23 essential 1 1 1 3.83295458705818 0.421696483083124 0.553077227179341 -1125.79099885752 2845.35932155589 -0.395658639781888 0.692621346829814 -6663.78174745662 6117.70021516944 -1.08926255178917 0.276860305086687 FDCSP other 1 1 1 -0.395658639781888 -1.08926255178917 7.70821205484491e-05 4.91448597271932 1.11366321199746 4.4129014227782 1.39717816304756e-05 3.04009768359566 3.52183220269777 0.863214800883161 0.388667904987373 GPR135 other 0.672310255423573 1 0.155156635006432 4.4129014227782 0.863214800883161 0.072664712621724 -6.0421665990408 2.89886466818875 -2.08432172268878 0.0379312113606865 -19.3084832742439 17.9242316465808 -1.07722794789517 0.282197522884504 P2RY13 other 1 1 1 -2.08432172268878 -1.07722794789517 0.00820874739455789 -7.20608339415305 15.0449387759147 -0.478970602771027 0.632286667144861 -94.3164685002947 30.2676239805045 -3.11608432036305 0.00199875383698173 TNFSF15 other 1 1 1 -0.478970602771027 -3.11608432036305 1.28887184790752e-10 49.6325787313349 7.0967854670874 6.99367043875212 1.56972403153551e-11 31.6641427787623 34.9770016359742 0.905284652707206 0.365995688227617 ZFP41 other 1.60528988656881e-06 1 2.16355063266539e-07 6.99367043875212 0.905284652707206 0.00628168666786771 61.8281625816436 51.24933376154 1.20641885549822 0.228547171665096 -169.053139607079 94.9591689183012 -1.78027189509762 0.0759802203230456 PHLDA2 other 1 1 1 1.20641885549822 -1.78027189509762 0.0155352343357809 83.1979856956019 29.0365226208313 2.86528751331657 0.00444195159450228 120.808778148576 64.516073232473 1.87253768085453 0.0620439836972167 ATG9B other 1 1 1 2.86528751331657 1.87253768085453 0.00606820026993048 45.1962294331008 18.9115933881067 2.38986892884046 0.0174345523349132 -68.8779015191906 50.2915863651222 -1.36957106540903 0.171784162129829 HKR1 other 1 1 1 2.38986892884046 -1.36957106540903 0.0348266125888395 30.7649995563138 12.4223917121434 2.47657619154286 0.013798278660273 66.8732397976794 57.9194299845509 1.15459077921721 0.249147298622135 PLAG1 other 1 1 1 2.47657619154286 1.15459077921721 0.00525582111569714 59.8971769842981 18.5473302799811 3.22942310726777 0.00136918315529047 16.6566033265211 77.5447926569351 0.21479976611984 0.830060257971967 ZBTB20 other 1 1 1 3.22942310726777 0.21479976611984 1.62808797472187e-06 304.362481542357 57.8922742846456 5.25739375941361 2.68638084219048e-07 281.593544650547 297.59688214664 0.946224781050605 0.344752380316536 C3orf58 other 0.0165755636706433 1 0.00328786151275693 5.25739375941361 0.946224781050605 0.0102552404045692 22.1639928698755 13.9254641918165 1.59161609010495 0.112458328165853 -34.931928752362 19.7118859870669 -1.77212514192103 0.0773252715397542 C5orf30 other 1 1 1 1.59161609010495 -1.77212514192103 0.340539875687224 14.7394837882085 11.9883831735822 1.22948053751641 0.21979491701121 27.978702529514 22.268617863946 1.25641845849863 0.209880718832946 AMIGO1 other 1 1 1 1.22948053751641 1.25641845849863 0.174976745233156 0.495025749280028 4.22295591880758 0.117222570824231 0.906757219426314 15.4866065542054 8.43485735522022 1.83602471292783 0.0672816520675912 GPR3 other 1 1 1 0.117222570824231 1.83602471292783 9.22432564183756e-16 456.299950678226 52.0773835233972 8.76195998735651 1.16777506678598e-16 -57.0524609639139 316.346475177894 -0.180348021680441 0.856994233189327 SIAH2 other 1.28218126421542e-11 1 1.70249926986729e-12 8.76195998735651 -0.180348021680441 1.2318540145337e-21 1179.28824002027 113.721830029819 10.3699372381806 6.50491881017425e-22 -97.5074915225714 456.307846218575 -0.21368795722146 0.830926488152679 COPG1 essential 1.80737621012384e-17 1 9.72745558873457e-18 10.3699372381806 -0.21368795722146 0.115317106021613 38.0579686633244 19.670548014535 1.93476910939149 0.0538997456441332 -57.9797551887632 99.4897270958398 -0.582771275801275 0.560457709790735 ADGRB1 other 1 1 1 1.93476910939149 -0.582771275801275 2.61512556553361e-05 100.588207977877 22.0796050143239 4.55570685764629 7.45079059261466e-06 -63.1827815606169 113.500837417176 -0.55667238232249 0.578142825412215 SLC9A9 other 0.240199283194262 1 0.0843727526707684 4.55570685764629 -0.55667238232249 0.006433640351133 44.886132556022 22.8111209361911 1.9677302435764 0.04996779772289 -114.499067360759 54.1812750032155 -2.11325900606738 0.035357300802825 LSM10 essential 1 1 1 1.9677302435764 -2.11325900606738 0.362785855296373 6.23827876432 9.26999960316759 0.672953509317126 0.501465602847708 -13.383565758689 18.4718710077737 -0.724537636336711 0.469268466106307 RELL1 other 1 1 1 0.672953509317126 -0.724537636336711 0.00245955865327637 66.5006621167366 34.231753495062 1.94266011311192 0.0529369276666648 -134.361900557989 67.5854733028885 -1.98802929078914 0.0476629150786087 RFX7 other 1 1 1 1.94266011311192 -1.98802929078914 3.13113146519553e-10 165.50153690413 36.7395597612225 4.50472291937509 9.42538823224733e-06 -228.390243210826 90.5627261545778 -2.521901149718 0.0121730115995258 SLC35C1 other 3.85974575714653e-06 1 0.106063893777479 4.50472291937509 -2.521901149718 0.127705672472571 -19.1661904761906 11.6226921469631 -1.6490319311433 0.100122405657785 -73.9228505519856 48.1022702189708 -1.53678506680609 0.125334101025628 TIGIT other 1 1 1 -1.6490319311433 -1.53678506680609 2.84571309950341e-06 114.34295012309 25.3701858833405 4.50698117265962 9.23423750045706e-06 -115.373290344027 72.4848632148113 -1.59168804667692 0.112442146855314 RNF41 other 0.0284286738640391 1 0.103977514255146 4.50698117265962 -1.59168804667692 0.31767294492281 40.7104998294011 27.724150648357 1.46841287748571 0.142974385355409 23.6392658307875 52.9198019336809 0.44669981683628 0.6553939693008 SLC2A4 other 1 1 1 1.46841287748571 0.44669981683628 1.64039029213922e-05 59.0272616859241 12.8752517318023 4.58455204725237 6.53391357594688e-06 51.4680583170767 43.4399967794894 1.18480806014649 0.236972531469388 IBA57 other 0.153685909730443 1 0.0742905973585161 4.58455204725237 1.18480806014649 0.0140568187534767 -5.37515029871465 188.058667826258 -0.0285823055158542 0.977215541455064 -1054.73623578873 358.965999698435 -2.93826222170011 0.00354034584835425 CLDN7 other 1 1 1 -0.0285823055158542 -2.93826222170011 0.664576590368801 8.30627849707871 10.5721983587485 0.785671836189611 0.432646610287302 -5.45081705996377 27.1985189063637 -0.200408598671468 0.841289546177157 ZNF329 other 1 1 1 0.785671836189611 -0.200408598671468 1.52874836620081e-05 20.6541070101799 10.8638789845794 1.90117241175985 0.0581832486489696 -88.2480357941011 24.6009052491499 -3.58718652424998 0.000386858559424188 ZNF101 other 0.143564759069918 1 1 1.90117241175985 -3.58718652424998 0.00551217147480218 51.0231500087105 47.7094135987665 1.06945665771146 0.285672505177724 -175.189070541852 71.242582260668 -2.45904998082265 0.0144611176213194 C5orf24 other 1 1 1 1.06945665771146 -2.45904998082265 3.83700995822671e-07 77.1691316446192 20.4895675152171 3.76626454351989 0.000197710071925869 -120.612222197685 47.0664565805629 -2.5625940629551 0.0108538909598717 ADO other 0.00409255482144461 1 1 3.76626454351989 -2.5625940629551 6.25699568849412e-29 245.889591894646 25.4074349226016 9.67785975418995 1.42944595790387e-19 -286.592728550819 89.2428746431417 -3.21137939243695 0.00145697961464401 COA4 other 9.43179530083604e-25 1 2.11672357446405e-15 9.67785975418995 -3.21137939243695 3.89284363604366e-07 143.510424980155 30.487178572294 4.70723863934638 3.75359364508269e-06 -142.530457379783 78.1374199632861 -1.82409986721794 0.069075340587019 PRKAG1 other 0.00414899274729533 1 0.0433014562896739 4.70723863934638 -1.82409986721794 0.198834395697974 18.9145795255439 18.7962612949886 1.00629477472665 0.315036480843012 -45.0930689006299 49.8792436162744 -0.904044761535179 0.366653872116238 GINS3 essential 1 1 1 1.00629477472665 -0.904044761535179 0.0112888289009736 24.6119054489983 14.7031733792317 1.67391792330782 0.0951361964532 -31.6465097435999 27.428978260187 -1.15376188800786 0.249469679825534 CCDC149 other 1 1 1 1.67391792330782 -1.15376188800786 0.0149621096312907 51.4625729892105 34.1592061386374 1.50655061421352 0.132912384130296 -136.220325455936 69.3728164041836 -1.96359802753693 0.0504422963617849 MRPS11 essential 1 1 1 1.50655061421352 -1.96359802753693 2.56379809992994e-06 143.732524908026 27.7927334524608 5.17158649234265 4.100567337474e-07 32.5139684945715 94.3850108953785 0.344482330256992 0.730709860482185 SNRPE essential 0.0256995121536977 1 0.00497726863422594 5.17158649234265 0.344482330256992 0.00925135960724746 -64.153674830503 23.7843948310482 -2.6973011205968 0.00736673137157736 -127.088787055646 54.6349836705488 -2.32614304091306 0.0206452102197353 RTKN2 other 1 1 1 -2.6973011205968 -2.32614304091306 0.00222990418706147 -72.4637776085958 86.5096897634704 -0.837637700548018 0.40285938204564 -595.19794400235 172.183589906347 -3.45676347162983 0.000620564142238246 CHST15 other 1 1 1 -0.837637700548018 -3.45676347162983 0.052878377253017 43.1861750640949 18.0884293987197 2.38750275726822 0.017543320877905 36.4221813231665 42.9555791885351 0.847903392555992 0.397125530396847 USH1G other 1 1 1 2.38750275726822 0.847903392555992 9.51381553828691e-05 855.492661121868 214.853732345988 3.98174447230097 8.47725030808511e-05 -259.821278307393 445.296081151367 -0.583479822314164 0.559982632410479 IDH2 other 0.821613109886458 1 0.885703112188733 3.98174447230097 -0.583479822314164 2.71649839343946e-07 7.12188367097915 1.32287988956849 5.38362078608832 1.41790579107308e-07 -1.31946951715531 3.44364737376143 -0.383160461552738 0.701855997690323 OGFRP1 other 0.00292621206941298 1 0.00175480020703205 5.38362078608832 -0.383160461552738 6.99441348236723e-12 220.050438093048 132.879588368119 1.65601384528252 0.0987054051207712 -1181.17052665349 218.05153693656 -5.41693281894699 1.19851422391986e-07 TMEM259 other 9.03398445382552e-08 0.00181071528949813 1 1.65601384528252 -5.41693281894699 5.39208102031404e-06 45.4365303268969 18.0481935909643 2.51751124553786 0.0123113939914187 -88.4127891541738 29.282764114951 -3.01927744276821 0.00273954962870202 WRB essential 0.0527021998925494 1 1 2.51751124553786 -3.01927744276821 1.06672283218804e-12 659.803624397579 89.4874816849965 7.37313881197533 1.47290314291548e-12 -495.401806643987 403.16000843204 -1.22879699445064 0.22006222635167 TNRC18 other 1.40434060857555e-08 1 2.06353730322459e-08 7.37313881197533 -1.22879699445064 3.53579016402197e-05 20.858377987893 5.52312134693007 3.77655616773417 0.00019048495402767 -4.4811959344538 15.1666507197576 -0.295463778869527 0.767836782666917 FAM181B other 0.320519378368591 1 1 3.77655616773417 -0.295463778869527 0.00779093998867525 129.901744919836 46.5466586881746 2.7907856026804 0.00557465846102787 -114.733574550404 153.600779951367 -0.746959583061565 0.455638145850171 TMEM30B other 1 1 1 2.7907856026804 -0.746959583061565 8.52896013831372e-10 139.469920462275 21.6777555535732 6.43378047683934 4.53751801630624e-10 -11.4981643240865 70.3384427528645 -0.16346913400522 0.870252264913849 DEXI other 1.03447757517607e-05 1 6.08934917788298e-06 6.43378047683934 -0.16346913400522 7.52345038527998e-05 207.647177924425 81.7928544041157 2.53869582419142 0.0116031116932348 -404.278237056405 170.883117088822 -2.36581731386763 0.0185897618922998 NOP10 essential 0.657399094665765 1 1 2.53869582419142 -2.36581731386763 0.0127381931225254 37.09179256402 12.7602633043823 2.90682031234273 0.00390686360612015 -34.8362179084038 48.8027173174945 -0.713817177059441 0.475862167690905 TDRKH other 1 1 1 2.90682031234273 -0.713817177059441 7.20835186436237e-05 14.9963319443631 5.13966229478609 2.91776600956371 0.00377659702617947 -25.4189799870883 11.6722501972678 -2.17772747820624 0.0301609625871391 ZNF708 other 0.631235372762213 1 1 2.91776600956371 -2.17772747820624 7.96964624240647e-21 408.800279894732 50.8033630546607 8.04671689657421 1.67898157169153e-14 -367.414346147291 139.004307479588 -2.6431867674406 0.00861720589452032 IST1 other 1.16332926200407e-16 1 2.40749167564849e-10 8.04671689657421 -2.6431867674406 5.29254685553589e-05 52.4456575968068 13.1995536597852 3.97329023000162 8.76915751383872e-05 -41.0315204578971 25.3018997147039 -1.62167745981746 0.105860346299547 ERCC6L2 other 0.470983744674138 1 0.914886203418794 3.97329023000162 -1.62167745981746 7.07500770905392e-05 218.663300914669 50.8712170155934 4.29836976079505 2.29650764144204e-05 -61.1531506310061 107.355221548951 -0.569633686640216 0.569332172113559 MRPL41 essential 0.620124425698576 1 0.251214970897345 4.29836976079505 -0.569633686640216 1.98104755842249e-08 303.189250139017 75.8878626514058 3.99522716210536 8.02544990777217e-05 -384.46617370189 168.509361878577 -2.28157159587919 0.0231711153780923 CREB3L2 og 0.000226988429244049 1 0.840023841846513 3.99522716210536 -2.28157159587919 1.71469230558726e-06 78.5857151419601 18.9244925407517 4.1525929941178 4.25055697907612e-05 -138.333289961049 73.4636718134438 -1.88301627928886 0.060631296143855 TP53TG1 other 0.0174229885170722 1 0.456339797273612 4.1525929941178 -1.88301627928886 0.0234317251097951 39.5938664941857 14.4988210643368 2.73083351525566 0.00666761459230338 37.5190494074445 26.2789544198723 1.42772230614595 0.154346954411477 UNC5C other 1 1 1 2.73083351525566 1.42772230614595 0.000100512231301616 119.253302752225 27.5315191971141 4.33151915440706 1.98782476475771e-05 16.195056286841 67.8497052581891 0.23869014942974 0.811499600659677 TSEN54 essential 0.865812360432125 1 0.218521576389815 4.33151915440706 0.23869014942974 0.344964343314887 38.1699428870555 104.823013056209 0.364137051341844 0.715998430089592 -269.657125695455 217.739570117133 -1.23843877137442 0.216469722438577 RGMA other 1 1 1 0.364137051341844 -1.23843877137442 6.31224642515163e-21 455.762958280654 57.5274971136924 7.92252368254304 3.88682461541184e-14 -447.197730060192 134.584031303735 -3.32281419814908 0.000994387242586452 MRPS16 essential 9.22029835321898e-17 1 5.55738183511584e-10 7.92252368254304 -3.32281419814908 1.02005832133835e-07 36.9401869411118 6.72114157380406 5.49611796381255 7.99080695154654e-08 -11.5193480002405 21.3973258058562 -0.538354563778611 0.590710090994513 RAD51B other 0.0011251243284362 1 0.00099845132859574 5.49611796381255 -0.538354563778611 0.236943759155924 -12.6705682345063 163.323552450141 -0.0775795532513558 0.938211144203435 701.650474192234 421.026332850305 1.66652396642778 0.0965906159328548 ARL6IP4 other 1 1 1 -0.0775795532513558 1.66652396642778 5.54300946117391e-07 503.718421573338 91.7896957475121 5.48774475687257 8.32663951202807e-08 57.2251563319565 505.04230087193 0.113307650137741 0.90985814999954 EXT1 ts 0.00584066906923895 1 0.00103991400865719 5.48774475687257 0.113307650137741 9.41757838282384e-11 1292.6037987996 188.954557991084 6.8408183033118 4.01107855308147e-11 -228.714548620151 623.385729494022 -0.366890895635018 0.713942892723836 SHMT2 other 1.17842158304275e-06 1 5.48835878418137e-07 6.8408183033118 -0.366890895635018 1.75468764580628e-08 78.9914604865934 39.6822811463584 1.99059777322913 0.0473754364177341 -263.578924446504 74.1047298943927 -3.55684346764549 0.000432067501928395 MOB2 other 0.000201508329244393 1 1 1.99059777322913 -3.55684346764549 0.00435183639432414 21.4736041312672 6.9144577479602 3.10560927754632 0.00207206879336813 41.1774237599505 20.8997047063313 1.97023950044023 0.0496892960249997 HHIPL1 other 1 1 1 3.10560927754632 1.97023950044023 3.48032071270568e-09 92.7117678615416 14.5357004030178 6.37821125167751 6.28919077417479e-10 -16.5594885880912 27.7894194381498 -0.595891851031548 0.55167003521102 CYB5D1 other 4.12383201248496e-05 1 8.41242157953621e-06 6.37821125167751 -0.595891851031548 1.59906736991466e-06 264.425426557715 96.0317061310612 2.75352211484023 0.00623478418547697 -480.772521008182 156.550169172732 -3.07104440415976 0.00231720709592976 BACE2 other 0.0162912983646905 1 1 2.75352211484023 -3.07104440415976 3.67525620314059e-18 211.374256354358 27.8484215643774 7.59017008794277 3.5238265080003e-13 -64.5443200920179 42.7831368601194 -1.50863926371381 0.132377656581356 UBE2E2 other 5.24789833246445e-14 1 4.97423349869322e-09 7.59017008794277 -1.50863926371381 0.134391700170941 273.849553675403 148.371819232053 1.84569788988773 0.0658625691510194 -135.133070400434 408.058467041738 -0.331161049984076 0.740740270385291 SYNM other 1 1 1 1.84569788988773 -0.331161049984076 0.437670457735723 -6.5291377127662 8.04452657726595 -0.811624854496437 0.417614013182714 -22.2148904588952 17.9570507633672 -1.23711241626682 0.216958118635482 GABRG3 other 1 1 1 -0.811624854496437 -1.23711241626682 8.07910438116714e-05 10.4415160705083 2.60187267425747 4.01307726308634 7.47384187668068e-05 -4.87121306458793 6.49153241979059 -0.75039493752464 0.453569996490248 PRR34 other 0.702784421438508 1 0.785201827564072 4.01307726308634 -0.75039493752464 3.36232927288626e-05 25.7361185356619 6.52076980852148 3.94679145122243 9.7410443174534e-05 -2.52229147144467 13.0085302122514 -0.193895192638227 0.846380971031773 NLRP10 other 0.305400367856259 1 1 3.94679145122243 -0.193895192638227 0.206928825904883 1.81185377946982 5.75704960738745 0.314719153565196 0.753182601308861 -26.6742379215995 16.0337639303351 -1.66362920381615 0.0971778976776259 FIGN other 1 1 1 0.314719153565196 -1.66362920381615 0.0461049568199366 139.815414823745 69.540757130113 2.01055353139376 0.0452112618724946 311.924780562936 131.181481972705 2.37781107418682 0.0180027726572384 B4GALNT4 other 1 1 1 2.01055353139376 2.37781107418682 1.38255580706091e-16 228.954622536318 25.2911550871153 9.0527546783721 1.45056967622585e-17 180.544767640253 126.309909906234 1.42937927652929 0.153879970719196 C8orf33 other 1.94000230846787e-12 1 2.12508457567088e-13 9.0527546783721 1.42937927652929 0.111601031348513 5.34830005396654 4.45053047965311 1.2017219247049 0.230359878675636 -15.3097409606045 10.8007470162732 -1.41747056361358 0.157318325254101 SPACA6 other 1 1 1 1.2017219247049 -1.41747056361358 5.11911486083959e-09 16.5559253412698 4.04672390515324 4.09119221605083 5.46042354852743e-05 -34.9844187270209 10.3322149633923 -3.38595536881231 0.000799457436123285 ZSCAN22 other 6.02263863377777e-05 1 0.580224606266525 4.09119221605083 -3.38595536881231 0.227198704613579 7.81607421874996 5.69371351964829 1.37275509064123 0.170789765230447 -9.28828869047624 13.0450417158825 -0.712016787126683 0.476973152949379 KCNJ14 other 1 1 1 1.37275509064123 -0.712016787126683 3.85602224125179e-14 179.606776461861 22.3283425857901 8.04389200728958 1.71150460723446e-14 -97.3788679612383 110.034176528592 -0.88498747419566 0.376827875600207 FBXL6 other 5.21835489908604e-10 1 2.45395530585277e-10 8.04389200728958 -0.88498747419566 0.00347054882105498 1076.67339838778 318.289384957233 3.38268710573696 0.000807213570924231 282.040062225993 1787.42364484627 0.157791390440206 0.87472101583455 C1S other 1 1 1 3.38268710573696 0.157791390440206 0.0255861179673803 2.27235302921058 0.835066941100478 2.72116272045928 0.00686121396824748 -0.0982173556355705 1.87131677444466 -0.0524856918811718 0.958174444759778 GLTPD2 other 1 1 1 2.72116272045928 -0.0524856918811718 1.1233451036657e-15 12.744907479043 3.32208651697361 3.83641648521949 0.000150651393469712 -24.0191504273348 6.40971342675379 -3.74730488372229 0.000212342411994212 KBTBD3 other 1.55976467643983e-11 1 1 3.83641648521949 -3.74730488372229 1.34352613132561e-06 38.0888029829465 11.9116668457888 3.19760479167634 0.0015251588155119 -52.7987881778803 20.0740080903628 -2.6302065805796 0.00894849138996846 YBEY other 0.0137832345812694 1 1 3.19760479167634 -2.6302065805796 7.40350067700217e-07 261.29753203001 52.6602655821747 4.96194861801946 1.13587333946443e-06 -213.921749636917 173.733083892276 -1.23132419481807 0.219105797964442 NXPH4 other 0.00773443715726417 1 0.0135032622595532 4.96194861801946 -1.23132419481807 3.95142990030367e-05 47.0241707085231 10.6208603929709 4.42752931199853 1.31596851638705e-05 -9.99397824303137 27.7440973407213 -0.360219981940545 0.718924042425726 CACNB4 other 0.356774605698419 1 0.146467295873878 4.42752931199853 -0.360219981940545 3.0232173962113e-14 94.1717996859988 13.3820556071488 7.03716995733387 1.26390874383751e-11 -98.4106341703108 38.4695818610044 -2.55814150842297 0.0109985366667393 TRAPPC6B other 4.10008743274176e-10 1 1.74558436611398e-07 7.03716995733387 -2.55814150842297 0.250589462352737 2.08871355399311 3.15681429703613 0.661652336012974 0.508674710311554 -7.63536628280054 6.5905748661443 -1.15852811596502 0.247520610340513 PGBD4 other 1 1 1 0.661652336012974 -1.15852811596502 7.33704816345233e-10 644.556103896105 111.789135393519 5.76582063746307 1.91408212603809e-08 -494.681743970314 257.836446067792 -1.9185873506814 0.055926048294057 NPLOC4 essential 8.91780105475765e-06 1 0.000245327906094302 5.76582063746307 -1.9185873506814 0.462871540349851 1.87764915951331 22.8498670540968 0.0821733078388596 0.934560273233233 128.913182515023 105.331991820563 1.22387491479921 0.221899772604171 TSHZ2 other 1 1 1 0.0821733078388596 1.22387491479921 6.54230837272731e-06 316.40012293508 81.1896893578929 3.89704807885586 0.000118617612763412 -462.354667323755 236.191223280066 -1.95754381091254 0.0511524661024616 CAPN12 other 0.0634734758322004 1 1 3.89704807885586 -1.95754381091254 4.44560197267043e-16 567.383593521117 69.0224382256439 8.22027746493483 5.16961629575908e-15 -322.850239928376 168.926841394496 -1.91118378383943 0.0568769744809854 EXOC7 essential 6.20428211305885e-12 1 7.44838315892968e-11 8.22027746493483 -1.91118378383943 1.51108112192421e-06 627.213029806216 143.793333739945 4.36190617112023 1.7443118367579e-05 -807.90472760502 337.841454561618 -2.391372392868 0.0173664299361066 KPNA2 other 0.01543116041709 1 0.192484811186234 4.36190617112023 -2.391372392868 0.0599257097155492 -12.6370703864553 6.35922947066033 -1.9872015068428 0.04776588386015 -39.1165542727759 21.8724671613935 -1.78839241061106 0.0746736643244577 NCF1B other 1 1 1 -1.9872015068428 -1.78839241061106 4.14125808242229e-12 99.9258858044286 13.8126872366668 7.23435520491393 3.5001485681087e-12 -10.1171161999885 56.4439818103714 -0.179241716751626 0.857861700586999 CEP97 other 5.37908012325831e-08 1 4.87605697023223e-08 7.23435520491393 -0.179241716751626 0.714013910810751 4.66243823186398 22.921521601655 0.203408757624857 0.838944839957666 38.9895710443113 47.5109200863947 0.820644411293487 0.412459740586631 FES other 1 1 1 0.203408757624857 0.820644411293487 7.79517882021418e-09 143.475355921766 24.5512577699351 5.84391061615844 1.26231841453129e-08 -46.912925932198 72.4195271667357 -0.64779387228237 0.51758568994881 GLRX5 essential 9.09385561166187e-05 1 0.000162573988607485 5.84391061615844 -0.64779387228237 0.274036195871216 13.9378086530652 14.4316349575657 0.965781679903034 0.334887325549287 38.4479816397762 24.2515408560716 1.58538304299747 0.113873213967426 CAV3 other 1 1 1 0.965781679903034 1.58538304299747 6.29280676120868e-06 396.20079852739 80.5826049460823 4.91670378231737 1.41105648098335e-06 13.8931039652452 194.346719618585 0.0714861768313408 0.943055622195708 MXRA7 other 0.0611409104919035 1 0.016692798170033 4.91670378231737 0.0714861768313408 3.62829190421598e-07 452.845911912199 95.8010813365349 4.72693946242025 3.43322142018388e-06 -487.314407796789 269.03182952439 -1.81136339390879 0.0710309706707523 LIMK2 other 0.00387973253317815 1 0.0397120721672669 4.72693946242025 -1.81136339390879 9.99662794981908e-05 103.261323754403 31.5888422032466 3.26891764788361 0.00119779670415184 -181.408815613143 85.7162524683473 -2.11638762065727 0.0350884579078125 MFSD5 other 0.861609362994907 1 1 3.26891764788361 -2.11638762065727 1.63191708627526e-05 32.7231712536619 6.96376222307182 4.69906498892881 3.89211347896185e-06 1.6919506520338 19.6919912445738 0.0859207497616587 0.931583318845035 RNASE10 other 0.152926950154855 1 0.0448721762989512 4.69906498892881 0.0859207497616587 0.403703607784184 -1.13806146149714 76.587267310884 -0.0148596692564772 0.988153512932421 -310.026231016616 235.899117185155 -1.31423226468999 0.189721215138471 ADI1 other 1 1 1 -0.0148596692564772 -1.31423226468999 6.12728010067631e-15 53.3092332154966 10.3510587824245 5.1501237058003 4.57359038454712e-07 -78.1238917855027 19.3219857933145 -4.04326411483721 6.61921851545141e-05 RWDD4 other 8.41704467429905e-11 0.950718355374285 0.00553770323760965 5.1501237058003 -4.04326411483721 0.922431249412023 2.32462830054482 5.87559328130546 0.395641459380988 0.692633183933867 2.59006373935267 10.9093953932938 0.237415882913623 0.812486096896081 CLEC4G other 1 1 1 0.395641459380988 0.237415882913623 0.0114747280180615 46.9781750924786 41.4079524140989 1.13452060180795 0.257430703118977 -126.862469985073 66.1866361948399 -1.91673844266109 0.0561671824809371 SATB1 other 1 1 1 1.13452060180795 -1.91673844266109 0.483109853931021 4.41762184120747 3.83300792173537 1.15252092649144 0.249972716877129 3.9449036642109 9.14213225616508 0.431508050165279 0.666391393467335 NXPH3 other 1 1 1 1.15252092649144 0.431508050165279 0.0563206992596282 -9.22465850977654 100.52300949966 -0.0917666368694203 0.926940871269988 -334.751470241944 145.535736720171 -2.30013244709503 0.0220838224008887 CSF1R other 1 1 1 -0.0917666368694203 -2.30013244709503 2.38881835225215e-12 516.249824065736 69.8622845550458 7.38953538885453 1.30962375119088e-12 639.356466992118 459.480459832914 1.39147694599377 0.16505346028155 EPHB3 other 3.11908012253564e-08 1 1.83569961204425e-08 7.38953538885453 1.39147694599377 0.326922510962437 4.99816016453296 3.8361699253667 1.30290374560381 0.193568402995813 -13.9532055910227 24.1108956037704 -0.57870955191066 0.563202692212816 ACTL10 other 1 1 1 1.30290374560381 -0.57870955191066 0.223579136405093 -64.8750077829953 56.7450597002474 -1.14327146937009 0.25378584297836 -199.241720503522 122.949125552902 -1.62052165566476 0.106111414172411 EPGN other 1 1 1 -1.14327146937009 -1.62052165566476 0.307471511016141 4.89072918168769 11.2636618382661 0.434204191488811 0.664441248787586 28.6803830281057 18.6747953154811 1.53578031478236 0.125608966590425 KRTAP11-1 other 1 1 1 0.434204191488811 1.53578031478236 2.98972868382327e-10 10.937144032401 3.46394750917652 3.15742198847611 0.00174381862480038 -23.8610887297268 5.97823963228171 -3.99132356636894 8.15765654261249e-05 C2orf82 other 3.68842827723277e-06 1 1 3.15742198847611 -3.99132356636894 0.687737415641582 -7.14133442446607 8.25253852825174 -0.865350025330802 0.387497006040096 -7.2693047495788 29.0379263594971 -0.250338287231083 0.802486898832305 HS3ST4 other 1 1 1 -0.865350025330802 -0.250338287231083 8.37799545911222e-07 203.921124291905 97.4616021457891 2.09232271789321 0.0371972427808859 -439.118818141146 138.992995059597 -3.15928740115904 0.0017325490546826 TRAK1 other 0.00872233107248174 1 1 2.09232271789321 -3.15928740115904 0.545440615207653 20.5240074211503 22.1317458162674 0.927356006685412 0.354440633880178 -17.9848184468593 51.0458432874949 -0.352326796631944 0.72482512074723 TSPAN10 other 1 1 1 0.927356006685412 -0.352326796631944 0.021011967881318 57.3633355276361 20.9705827312052 2.73541924241698 0.00657976166202345 17.7548677880517 79.7833046983846 0.222538635810747 0.824037462912378 PLCB1 other 1 1 1 2.73541924241698 0.222538635810747 0.0310384034145927 53.9100081007438 38.0866624373263 1.41545634746693 0.157916409184905 -178.182189410119 89.1956074621847 -1.99765654923827 0.0466081437930392 SKA2 other 1 1 1 1.41545634746693 -1.99765654923827 0.00909889297384676 113.181158207456 37.4734832942626 3.02029990963731 0.00273258173053366 143.8235235319 81.7626159463111 1.75903769549571 0.0795450650977842 NDN other 1 1 1 3.02029990963731 1.75903769549571 0.297883157148081 43.0438664271017 28.0901448110424 1.5323476157439 0.126443546146421 38.9434473660059 51.3516869373848 0.758367440070494 0.448799869495848 NTM other 1 1 1 1.5323476157439 0.758367440070494 4.42308473709415e-09 630.17530901537 126.767861607075 4.97109678294204 1.090428894035e-06 -423.614027268169 211.871136385867 -1.99939470044975 0.0464161893514382 TTC3 other 5.21968229824481e-05 1 0.0129771942679105 4.97109678294204 -1.99939470044975 0.0486952104954043 36.9578570878316 16.6760886038812 2.2162185609418 0.0273818363528769 58.2442720312843 37.3455436610857 1.55960434154759 0.119844910996578 PPP1R27 other 1 1 1 2.2162185609418 1.55960434154759 0.107779954098745 15.2956964956372 7.66751482171317 1.9948701569278 0.0469048807037882 -2.41192425618304 21.7876489988235 -0.110701446324625 0.911922495978714 BRICD5 other 1 1 1 1.9948701569278 -0.110701446324625 0.13798227644027 13.9445057111073 6.98635889339711 1.99596183418038 0.046790616184225 4.91372405639488 17.1241184566102 0.286947562810049 0.774339348592404 GALR2 other 1 1 1 1.99596183418038 0.286947562810049 0.0148674249903653 17.9247029369802 7.45316444528354 2.40497886080096 0.0167408844590901 -8.30594556760971 10.9437170647668 -0.758969326276777 0.448429583933772 IGIP other 1 1 1 2.40497886080096 -0.758969326276777 3.40725374759033e-20 839.462075356758 102.479027757915 8.19154995634628 6.58637392023264e-15 -442.984537218256 319.077341993537 -1.38832965841626 0.166020816426053 TSKU other 4.9510804206235e-16 1 9.47910934599882e-11 8.19154995634628 -1.38832965841626 0.000217352953593867 2945.1583440212 1231.6899598787 2.39115235161229 0.0173748211811742 -5599.61547878806 2419.13736563153 -2.31471579842522 0.0212630660551641 ANXA2 other 1 1 1 2.39115235161229 -2.31471579842522 0.244422200883102 -0.157047906577883 4.27738322359411 -0.0367158840740769 0.970734508429156 21.4438839594894 13.1732629429147 1.62783389752522 0.104547337725953 RGS6 other 1 1 1 -0.0367158840740769 1.62783389752522 0.944822631214579 -2.13029706587615 6.70642227140608 -0.317650302898316 0.750958034788238 -2.1692010868002 15.9433533957218 -0.136056765033025 0.891862224969099 HOXB4 other 1 1 1 -0.317650302898316 -0.136056765033025 0.000106711166498853 119.297070173677 49.6165271851058 2.40438170387485 0.0167695509605187 -275.745528806888 97.3234716886656 -2.83328907222903 0.00490050681553001 PAQR7 other 0.916435497892152 1 1 2.40438170387485 -2.83328907222903 0.212310056276162 55.2420689112279 33.6832298408113 1.64004666928632 0.10197806178155 -31.2770942433809 67.0490318900603 -0.466480922419069 0.641188704857375 PAPPA other 1 1 1 1.64004666928632 -0.466480922419069 0.136453874427346 5.10953136624002 2.6800215147052 1.90652624921261 0.057477487871247 -5.13092317956345 12.9753734316943 -0.395435492209448 0.692785003624471 MAFA other 1 1 1 1.90652624921261 -0.395435492209448 2.12802289626192e-05 645.03119861904 137.29675689232 4.69808037144628 3.9096956239767e-06 263.539923808774 284.555018576496 0.926147516663557 0.355069449367602 NGRN other 0.197161321338667 1 0.0450670614575794 4.69808037144628 0.926147516663557 0.0534603801786921 9.7839873014292 4.08364499107636 2.39589565763168 0.0171574481934457 11.3547119781625 8.10841336959066 1.40036175520436 0.162379951809094 GRID1 other 1 1 1 2.39589565763168 1.40036175520436 0.00337397312966595 1588.96467827669 733.867594495658 2.16519259086332 0.0311233832645791 -2500.48095575307 1447.53378914349 -1.7274076601919 0.0850746712372202 RPS17 essential 1 1 1 2.16519259086332 -1.7274076601919 0.00923388433893949 152.420749328344 83.9368721884063 1.8158974161703 0.0703218381573068 -470.426663568105 215.430185457751 -2.18366178615374 0.0297130148734455 HCAR2 other 1 1 1 1.8158974161703 -2.18366178615374 0.0192291295857317 3.73334241992153 1.32239376694806 2.82317000672021 0.00506172021710934 1.54899301963636 8.45535546185826 0.183196676547048 0.854763075002495 CCDC87 other 1 1 1 2.82317000672021 0.183196676547048 0.848770981332907 76.9555602924228 134.73431742775 0.571165251448947 0.568288539108048 -15.4513260596103 457.562047293824 -0.0337688104837248 0.973082560805621 C1orf116 other 1 1 1 0.571165251448947 -0.0337688104837248 0.633564224157547 -12.6974505109095 25.1495436869197 -0.504877967925654 0.613992056529306 50.2783734240332 71.8544689598967 0.69972507140919 0.484607357321344 TMEM198B other 1 1 1 -0.504877967925654 0.69972507140919 0.0641328564688852 234.546284063503 102.042737718948 2.29851030368769 0.0221831608317873 356.939810753318 301.356546282786 1.18444352762914 0.237124829413401 CRIP2 other 1 1 1 2.29851030368769 1.18444352762914 6.23174528371649e-17 77.4099553095918 13.417271454109 5.76942603973962 1.88210391083963e-08 -149.093195558422 35.9169184553495 -4.15105755088006 4.25114019347133e-05 DDX28 other 8.77554370852956e-13 0.614714871975955 0.000241304542408749 5.76942603973962 -4.15105755088006 0.000362625523388015 179.996663113612 50.7956435668818 3.54354528211879 0.000453578765606437 -353.255577911699 174.117796737076 -2.02883096691791 0.0433031478417786 ACBD3 other 1 1 1 3.54354528211879 -2.02883096691791 3.67103551247289e-12 512.521100741511 86.5001902729922 5.92508639719761 8.13221626317166e-09 -866.085842956208 279.376187836143 -3.10007037344276 0.00210832519798342 C16orf72 essential 4.77381458041975e-08 1 0.000105369126121915 5.92508639719761 -3.10007037344276 8.01411458262244e-05 69.5090057441965 18.2367348550321 3.8114830476365 0.000165852761349527 -57.1221602964085 47.2659325419376 -1.20852709815311 0.22774246232378 RRP7BP other 0.697468392125631 1 1 3.8114830476365 -1.20852709815311 0.891943647156095 -4.44797030637128 9.79761202678648 -0.453985143952487 0.650147270210125 3.10885804771025 21.9556479041842 0.141597189993094 0.887487287023578 VMO1 other 1 1 1 -0.453985143952487 0.141597189993094 3.53871164198006e-14 112.937298761078 17.7636646587185 6.357770253541 7.10381735460802e-10 -176.775326169829 50.1783269660398 -3.52294181289601 0.000489307250342609 ALG12 other 4.7917694344052e-10 1 9.49354151269816e-06 6.357770253541 -3.52294181289601 0.149055616218692 -46.7483694827849 28.1839476022848 -1.65868778009633 0.0981646747139036 -87.6587144327805 63.3472792038842 -1.3837802591434 0.167396250984691 LCK og 1 1 1 -1.65868778009633 -1.3837802591434 0.0466616203346778 1114.29282686239 506.761916623453 2.19884878936228 0.0286039796733714 -170.903109417893 847.194651739488 -0.201728267602951 0.84025733891197 COL18A1 other 1 1 1 2.19884878936228 -0.201728267602951 0.0666438462968249 -1.35731564205245 3.70634647593603 -0.366213911965601 0.714447458598618 -21.7148680807306 9.75619430175442 -2.22575190787516 0.0267271494639499 ADGRG3 other 1 1 1 -0.366213911965601 -2.22575190787516 0.904374659602893 -9.96999108800599 33.1329986936483 -0.300908202731353 0.763681761371725 -49.7154236910508 148.365005680368 -0.335088611111948 0.737779872619535 TCHHL1 other 1 1 1 -0.300908202731353 -0.335088611111948 5.99106757585601e-09 2024.55110627896 319.566029451797 6.33531389350737 8.29477754253633e-10 -657.555121278349 2050.01261495841 -0.320756621925319 0.748610258620625 RPL35A other 7.02872047999428e-05 1 1.1063574286235e-05 6.33531389350737 -0.320756621925319 0.311814367835625 2.66105389693497 2.04842143466823 1.29907540113491 0.194880316961083 -2.46731849634405 6.22148136608247 -0.396580549094801 0.691948778331351 SLC25A18 other 1 1 1 1.29907540113491 -0.396580549094801 6.85012042780939e-07 53.8752662077867 17.0926432022618 3.15195640430016 0.00177727266844361 -63.5174476416146 31.6279081406594 -2.00827216770493 0.0454650047271547 ZNF721 other 0.00717002105178809 1 1 3.15195640430016 -2.00827216770493 1.19603471778333e-07 30.8547709045697 11.1537983416739 2.76630166328965 0.00600656098773156 -67.0480746036676 26.448875169723 -2.53500665617795 0.0117312346707763 C11orf54 other 0.00131360493054143 1 1 2.76630166328965 -2.53500665617795 1.79388641264336e-14 124.165472969731 15.0036243691686 8.27569858552857 3.49578348043107e-15 -10.808811642559 62.524493291647 -0.172873238526557 0.862860358186757 CEP63 other 2.44417023722658e-10 1 5.04476514061007e-11 8.27569858552857 -0.172873238526557 1.00223136775452e-24 821.240627477216 124.1383255929 6.61552847241068 1.56285305237048e-10 -708.988039972419 230.229354194112 -3.07948585641539 0.00225382286549099 SRPRA other 1.49232250658649e-20 1 2.11563417699391e-06 6.61552847241068 -3.07948585641539 0.302093784028662 35.478972184475 29.248993235199 1.21299806455487 0.226025222347843 79.300731475135 69.4591784286394 1.14168830195143 0.254437202294334 OTOP3 other 1 1 1 1.21299806455487 1.14168830195143 0.750481920079406 -25.6819699305907 120.172165117881 -0.213709804640687 0.8309111865143 -253.839734774295 335.204663536918 -0.757267909389745 0.449453653546472 EWSR1 essential 1 1 1 -0.213709804640687 -0.757267909389745 0.0105793673467834 5.17886854522927 2.15556752159685 2.40255454461141 0.0168502298639923 -3.53135158938138 4.19166200705166 -0.842470500589163 0.40015386036269 ODF3L1 other 1 1 1 2.40255454461141 -0.842470500589163 0.00437180613950403 93.9092069187233 34.7748224738855 2.70049421500988 0.00729208506449255 -57.5531251147382 75.9582295980566 -0.757694398872755 0.449191547390208 HMGN4 other 1 1 1 2.70049421500988 -0.757694398872755 0.804078660405784 1.87873759230711 17.03342865751 0.110297088747237 0.912242906472061 -14.6075156021991 27.6270219136988 -0.528740146072566 0.597352255625394 SPATA13 other 1 1 1 0.110297088747237 -0.528740146072566 9.34342318486479e-05 113.484965590229 26.570547158239 4.27108124324192 2.57005854116772e-05 -36.450888343287 64.5254263308141 -0.564907361578793 0.572533812613828 GJC1 other 0.807738934331562 1 0.280316285085164 4.27108124324192 -0.564907361578793 0.25640719691041 -0.0239643740391731 2.19322029537142 -0.0109265695241594 0.991288927283125 8.62759866340223 5.36998988236008 1.60663220088051 0.109133819259226 SOX1 other 1 1 1 -0.0109265695241594 1.60663220088051 7.56025046940762e-32 126.682253007139 23.1099971639863 5.48170785605097 8.55445882243298e-08 -270.928353026626 34.3926377298813 -7.87751015651921 5.25806588665252e-14 CNOT10 other 1.14545354861995e-27 8.0669246833023e-10 0.00106802712994749 5.48170785605097 -7.87751015651921 3.7757953558275e-15 309.886400775425 38.2420920501114 8.10328055194675 1.17199956475091e-14 -29.7046228581247 112.938020289022 -0.263017031661322 0.792708316283458 MTA1 other 5.20002536404563e-11 1 1.68334297485173e-10 8.10328055194675 -0.263017031661322 0.00186400616088012 14.6016501121436 11.7254869414448 1.24529157595432 0.213935686879231 -37.1424223005446 16.8029742512507 -2.21046713189957 0.0277799016559544 ZNF662 other 1 1 1 1.24529157595432 -2.21046713189957 0.916248403676508 -12.1202619675657 57.6715530683245 -0.210160145214168 0.833678553444085 -44.0335714780108 106.746963420615 -0.41250420683636 0.680250502253428 CADM1 other 1 1 1 -0.210160145214168 -0.41250420683636 0.631257120409903 -9.30009557135371 9.69219353991657 -0.959544971223693 0.338013260720343 -6.97709521123385 31.3811151512212 -0.222334202516775 0.824196454194216 ZNF320 other 1 1 1 -0.959544971223693 -0.222334202516775 0.502370155596551 39.8006588999235 35.9300795421642 1.10772532115375 0.268812381954085 -19.9407785841609 140.747012472523 -0.141678165908166 0.887423374360126 C12orf60 other 1 1 1 1.10772532115375 -0.141678165908166 1.91491374719927e-08 542.296075129398 91.6576277314605 5.91654059297959 8.49794649703389e-09 595.897936834276 205.256919937719 2.90318074058156 0.00395217974741332 PYCR1 other 0.000219583159391341 1 0.000110005917404104 5.91654059297959 2.90318074058156 0.000168477128713449 216.771345955927 55.2046531335608 3.92668613334959 0.000105573325925824 -147.279262514189 105.540511866053 -1.39547610590622 0.163842940154866 NAA38 other 1 1 1 3.92668613334959 -1.39547610590622 0.278933299438212 46.325716015784 58.9516233035264 0.785825960673977 0.432550931006161 -150.974142260432 110.984332257071 -1.36031941797635 0.174686327367195 SPNS2 other 1 1 1 0.785825960673977 -1.36031941797635 0.756065663066611 -0.497292864119134 3.4497523420138 -0.144153207191922 0.885470230734214 3.8175414237731 6.40526164867698 0.596000855727982 0.551595983077723 MCEMP1 other 1 1 1 -0.144153207191922 0.596000855727982 4.66300113052623e-15 226.369794813895 42.400510641279 5.33884595704639 1.77650959183051e-07 -179.186782796379 79.0270012954786 -2.26741214849348 0.0240316980174547 AP2A2 other 6.41628955560409e-11 1 0.00218972572289028 5.33884595704639 -2.26741214849348 0.0932710700733297 -1.94129028838004 12.3234246998335 -0.15752847407801 0.874928031426158 -93.4069068757607 42.865373876465 -2.17907598671489 0.030057406565069 SLC8A1 other 1 1 1 -0.15752847407801 -2.17907598671489 0.00850406943903742 8.69067724448492 2.82744190849232 3.0736890538342 0.00230281643169578 2.01080040537748 9.1249795230785 0.220362182763462 0.825734615875507 SLC25A21 other 1 1 1 3.0736890538342 0.220362182763462 0.551649296016647 -25.5535119114345 44.5591614712711 -0.573473805783122 0.566730537899176 -78.7799344344765 73.1650614077765 -1.07674254512555 0.282414042830591 PCP4 other 1 1 1 -0.573473805783122 -1.07674254512555 0.114469913219865 116.287161009431 64.1523645020652 1.81267147223681 0.0708313468030307 -114.462896996001 204.955475221674 -0.558476892955413 0.576914277565707 ABAT other 1 1 1 1.81267147223681 -0.558476892955413 0.050075718338649 131.831317596252 55.0364706572716 2.39534468729299 0.0171791511881867 0.0796312987849968 123.610584390019 0.000644211004890505 0.999486395430659 SLC25A10 other 1 1 1 2.39534468729299 0.000644211004890505 7.69530517932091e-06 180.424058399673 73.3090614231479 2.46114265954444 0.014380314273479 -369.702762656934 150.057639521057 -2.46373835971913 0.0142785837374032 CAMK1D other 0.0742366090649088 1 1 2.46114265954444 -2.46373835971913 1.74300452651135e-22 163.313326804868 15.6816719721139 10.4142802562942 4.59470266558475e-22 -16.5354914049533 44.1193735621239 -0.374789804793351 0.708065057834931 LYSMD4 other 2.56936297253038e-18 1 6.87321571744822e-18 10.4142802562942 -0.374789804793351 0.387430195055568 0.0100907214254561 3.09123098032752 0.00326430522004763 0.997397506271153 10.8120201361727 8.04692060937382 1.34362207122782 0.18002557870644 WBP2NL other 1 1 1 0.00326430522004763 1.34362207122782 0.0613522862796614 30.9220888283759 13.3086089985711 2.32346512183926 0.0207804445106838 25.3739820713369 20.1592870119703 1.25867457793871 0.209065383091459 NKX2-5 other 1 1 1 2.32346512183926 1.25867457793871 0.00433344276722971 60.711382391548 20.2256640145021 3.00170033221244 0.00289602103934475 -38.664089857849 47.6740190302545 -0.811009657761649 0.417962901810069 AFMID other 1 1 1 3.00170033221244 -0.811009657761649 0.0001812602385175 496.252333659482 149.141796763398 3.32738604756619 0.000980772144090335 -635.784790528412 365.706741526877 -1.73850989969154 0.0831012044428548 GAS6 other 1 1 1 3.32738604756619 -1.73850989969154 0.254413963958204 1684.1674973799 1851.02237076148 0.909857991984755 0.363593064824883 7373.06301437198 4835.29045050313 1.52484387232721 0.128301389348042 NEB other 1 1 1 0.909857991984755 1.52484387232721 0.0154553549472878 15.3606930662371 5.37467673497743 2.85797524645017 0.00454746141232676 4.94335074484386 16.1992990723916 0.305158311032653 0.760447119607837 BEGAIN other 1 1 1 2.85797524645017 0.305158311032653 0.309833409312468 31.0607675435367 31.3630634213501 0.990361404632189 0.322772372440523 100.230062322597 72.2648051173444 1.38698308477886 0.166446583689701 GPC6 other 1 1 1 0.990361404632189 1.38698308477886 4.48477765306574e-08 429.039893201198 79.5107204204906 5.39600057617678 1.32853854938851e-07 -73.9920545977176 114.815174144544 -0.644444910256958 0.51974864999366 ARHGEF37 other 0.000503819921545406 1 0.00164645782425718 5.39600057617678 -0.644444910256958 0.509622635332142 0.642293956389422 3.88704795592947 0.165239524613953 0.868860121134918 -8.00831373707905 7.57278335348388 -1.05751258992439 0.29107786624916 FAM43B other 1 1 1 0.165239524613953 -1.05751258992439 0.00229657811539056 -5.14869193182634 18.9136556093537 -0.272220877770455 0.785635778649062 -105.094816823697 36.6683102126657 -2.8660938072733 0.00444374112501895 CSMD1 other 1 1 1 -0.272220877770455 -2.8660938072733 9.88987563161542e-27 26.5797485962206 2.27283316736251 11.6945444909469 1.5182118236649e-26 -0.272452542098765 10.4045462161987 -0.0261859130073917 0.979125373928293 PTGDR2 other 1.48288795220442e-22 1 2.29416988674002e-22 11.6945444909469 -0.0261859130073917 0.000477296972173404 9.11914411579611 6.00913469100765 1.5175469655294 0.130119011553738 -42.963504090623 13.6870375948739 -3.13899218825217 0.00185374300974066 CEP57L1 other 1 1 1 1.5175469655294 -3.13899218825217 0.055406939191625 0.820482855077893 9.14163068911793 0.0897523519577951 0.928540514648197 -34.1017196549426 15.2759516940788 -2.2323793854468 0.0262859099236466 RIPPLY3 other 1 1 1 0.0897523519577951 -2.2323793854468 0.00156814180903975 8.17222902679256 2.27304544061371 3.59527745498397 0.000375489079226528 2.99316867944855 9.03368040419425 0.331334356045943 0.740610181736202 GPR19 other 1 1 1 3.59527745498397 0.331334356045943 9.33036763536673e-06 12.4177641302853 2.6590278611783 4.67003911902699 4.45423960972394e-06 -8.66201038771636 7.68914362951845 -1.12652472174705 0.260795542049169 GJD3 other 0.0892822879028243 1 0.0511435791988503 4.67003911902699 -1.12652472174705 0.0772399938217733 26.3317333750968 12.4032453188143 2.12297126262226 0.0345236072670735 36.5212107478349 42.1852914256825 0.865733280808881 0.387285036347371 RABIF essential 1 1 1 2.12297126262226 0.865733280808881 0.0322733453636725 24.5003776581324 42.4842431967915 0.576693282369279 0.564552107209677 313.084885927878 119.1463028018 2.62773479802134 0.00900971732162474 TMEM119 other 1 1 1 0.576693282369279 2.62773479802134 4.9120531772496e-07 50.1782285060269 14.2693252808512 3.51651024266466 0.000500649208887894 -66.7707856098964 29.9751943165116 -2.22753470435773 0.0266088281088015 FANCF other 0.00519646105621235 1 1 3.51651024266466 -2.22753470435773 0.842181491371333 1.8664499829631 9.34279937553758 0.19977416916926 0.84178692956295 -15.4101483535982 32.1164626711873 -0.479820847998403 0.63168990362632 CALN1 other 1 1 1 0.19977416916926 -0.479820847998403 0.0690751669137824 63.5971577992843 31.8428247901472 1.99722098207074 0.0466503098852827 -57.81892348923 82.891470969072 -0.697525605629596 0.485981983717279 SMDT1 other 1 1 1 1.99722098207074 -0.697525605629596 0.0180176052573752 13.5556768062565 7.83293245927161 1.73060049690727 0.0844961838677525 -13.5770320859667 12.8054839274377 -1.06025138627333 0.289837398299983 C2CD4C other 1 1 1 1.73060049690727 -1.06025138627333 0.515000998590145 -35.4286798279622 30.8913083402397 -1.14688181665042 0.252289949345605 -31.5271509705296 80.9329479169488 -0.389546554054622 0.697131812440158 CHST6 other 1 1 1 -1.14688181665042 -0.389546554054622 4.52187830546091e-06 397.669609374999 108.141939591435 3.67729311012373 0.000276392319396015 -634.916726190479 247.76731536255 -2.56255239017877 0.0108478448546296 RUVBL2 essential 0.044472673134208 1 1 3.67729311012373 -2.56255239017877 0.0705367358181692 3.12817028555779 15.6260962746664 0.200188852709765 0.841460445417013 -69.667401107965 32.3859369759413 -2.15116212817061 0.0322140569851749 GDPGP1 other 1 1 1 0.200188852709765 -2.15116212817061 0.547307093094079 6.58901670854908 11.3086412251054 0.582653262880191 0.56053835620237 -15.3379220822446 23.8187929741602 -0.643942037654213 0.520075723926674 CTNNA3 other 1 1 1 0.582653262880191 -0.643942037654213 0.036480939660581 2.44279919947159 1.17695897291324 2.07551771615719 0.0387497281051223 -4.3582268236346 3.86467598866697 -1.12770820540064 0.260301400286531 RIMBP3C other 1 1 1 2.07551771615719 -1.12770820540064 0.235615518395344 9.19951831573303 19.255650893171 0.477756808469956 0.633152568477474 -46.0115676843801 35.8507752937084 -1.28341904205499 0.200282716880184 PRR36 other 1 1 1 0.477756808469956 -1.28341904205499 9.86267780591695e-06 7.24136739686632 3.5924762516697 2.01570362323222 0.0446665326674443 -19.8065755317759 6.00583147051512 -3.29789066326849 0.00108376893770356 LINC01547 other 0.0941885730465068 1 1 2.01570362323222 -3.29789066326849 1.52659136481608e-08 601.446691691413 217.483622301332 2.76548038572802 0.00601386037705649 -1446.93472836947 363.584862260922 -3.97963413375307 8.54370021409917e-05 PTTG1IP other 0.000175603804694793 1 1 2.76548038572802 -3.97963413375307 1.63258571252707e-24 427.512599841892 49.4812480263536 8.63989120917484 2.72571852116457e-16 -307.574144786905 75.1888771368537 -4.09068676776591 5.44788891913223e-05 DDX41 essential 2.42798147167026e-20 0.784986314357763 3.96401244532963e-12 8.63989120917484 -4.09068676776591 1.46749098113296e-08 19.0441305406722 3.51724653370541 5.41449976797879 1.21598780386066e-07 -26.1938955516646 15.8671137221675 -1.65082925668264 0.0997637661369242 ABHD16B other 0.000168922886838216 1 0.00150879766703031 5.41449976797879 -1.65082925668264 0.0696259522007819 -16.224123509182 7.01371014704464 -2.31320131129433 0.0213492538951507 -9.15125448939484 19.3981880444601 -0.471758211046332 0.637422906501876 CCDC60 other 1 1 1 -2.31320131129433 -0.471758211046332 0.28650821381285 -1.80629790009601 1.1572473650279 -1.56085721573664 0.119555186710857 -1.91540593915896 4.77096230016965 -0.401471614875441 0.688343439963871 PLGLB1 other 1 1 1 -1.56085721573664 -0.401471614875441 0.000377148918889725 445.217623088943 168.613953387326 2.64045539615708 0.00868673638187422 -1114.43664787524 459.799684248498 -2.42374383030882 0.0159172263093186 DAZAP2 other 1 1 1 2.64045539615708 -2.42374383030882 0.742315380605933 12.254862923657 19.5170603545241 0.627905160974527 0.53051390389997 0.942970274676754 29.6110479011789 0.0318452179680954 0.974615339077723 CCBE1 other 1 1 1 0.627905160974527 0.0318452179680954 1.59937164868453e-06 270.277440299816 106.768352474294 2.53143777192675 0.0118380266370435 -823.529690370669 226.881706645809 -3.62977563306284 0.00033013557587452 SELENOF other 0.0162927989851494 1 1 2.53143777192675 -3.62977563306284 9.86433132332857e-14 150.854376322769 18.6252567301756 8.0994521851805 1.18259721413507e-14 135.562301995609 91.6035872645816 1.47987983924756 0.139892198329721 ZNF623 other 1.32625934642153e-09 1 1.69844611894079e-10 8.0994521851805 1.47987983924756 0.318812880154173 1.06895579750885 6.4562653962701 0.165568750957233 0.868601548998631 -22.2062700917872 15.3350066359108 -1.44807697962032 0.148580730874027 EPHA10 other 1 1 1 0.165568750957233 -1.44807697962032 5.75537640022857e-07 2.70578769273465 14.6330756328805 0.1849090212214 0.853417898050066 -99.4493439879977 19.9719407101544 -4.97945319542402 1.04610276221728e-06 CCDC125 other 0.00605868473652061 0.0156716654807771 1 0.1849090212214 -4.97945319542402 1.12368236649966e-16 63.9452587205584 12.3765712962008 5.16663760828391 4.23799872748632e-07 -86.0023448113453 28.8640627829443 -2.979564777768 0.00311108121302465 JRKL other 1.57776241080217e-12 1 0.00514069245644091 5.16663760828391 -2.979564777768 0.778068196404127 -120.011879116689 386.038053372587 -0.310880956082481 0.756093527330353 -583.84268296647 830.325156900247 -0.703149456709296 0.482473859583446 GBP6 other 1 1 1 -0.310880956082481 -0.703149456709296 1.24393433771678e-42 227.721390970496 15.399886065413 14.7872127107447 6.84791385606485e-38 -224.463902039293 51.8486851483074 -4.32921107637038 2.01668780802131e-05 KIAA2026 other 1.90222438923649e-38 0.294496920605351 1.04601884151391e-33 14.7872127107447 -4.32921107637038 0.147990333998467 161.394966432844 95.3863427000381 1.6920133623362 0.0916229901706037 -149.233493269737 227.724811344797 -0.655323819958219 0.512733067517359 FHL3 other 1 1 1 1.6920133623362 -0.655323819958219 0.127870247182133 -3.60185899476173 4.99602665692858 -0.720944711086881 0.471473196357503 23.2883249086956 12.9803986344785 1.79411476985285 0.0737446764552935 PMCH other 1 1 1 -0.720944711086881 1.79411476985285 0.000154012078078369 5.46464646112918 2.89951168953465 1.88467819628146 0.0603879686521443 -12.7070060101259 5.15047327818495 -2.46715307968823 0.0141473985021336 C19orf71 other 1 1 1 1.88467819628146 -2.46715307968823 0.00182321693555452 15.5733074622937 30.3640846730688 0.51288578694112 0.60838730587969 -205.726956813579 64.0643429149743 -3.21125523891844 0.00145670955796519 CCDC159 other 1 1 1 0.51288578694112 -3.21125523891844 6.03260562485393e-07 88.2027944448075 122.176145731691 0.721931387805507 0.470863856313616 -929.226465028593 198.045345812514 -4.69198839900169 4.01543101200651e-06 RIPK4 other 0.00633906199059651 0.0596532431143687 1 0.721931387805507 -4.69198839900169 1.51322894320281e-07 181.490107921635 54.2204212410776 3.34726480848765 0.000914039180813361 -512.377430717356 129.445524890167 -3.95824754198418 9.31824299282362e-05 SF3A3 essential 0.00165335394334339 1 1 3.34726480848765 -3.95824754198418 0.199172861040315 -44.942268734552 25.8906372457219 -1.73585023450816 0.0835619964973758 -74.7569967282545 83.6209436248681 -0.893998482767928 0.37200093473973 GRIN2A other 1 1 1 -1.73585023450816 -0.893998482767928 9.18933419135183e-10 46.9178423868861 11.0606746425431 4.24186081800327 2.91782231655776e-05 -47.0295708542168 15.2179337450983 -3.0904044952466 0.00217721406018501 GTF2H2C essential 1.11264458388888e-05 1 0.317021394694001 4.24186081800327 -3.0904044952466 3.7439199091413e-11 94.1834655519691 14.3309133133805 6.57204907268764 2.02253130192678e-10 -29.3157361393505 31.7269382932504 -0.92400142328222 0.356183971876184 ASB7 other 4.748039228773e-07 1 2.73163077638231e-06 6.57204907268764 -0.92400142328222 0.0910612806199648 12.4668696356323 7.51509795501843 1.65890979868162 0.0981137242436994 -10.4541804456533 14.5800572866087 -0.717019161183621 0.473885294252133 SH2D7 other 1 1 1 1.65890979868162 -0.717019161183621 0.890467078420385 0.572142823827146 6.55383571085927 0.0872989267764437 0.930489200162693 9.23609300572299 19.3251943599131 0.477930148267059 0.633030363718351 GPR132 other 1 1 1 0.0872989267764437 0.477930148267059 0.0133635122303106 -79.5395589270593 198.059531095281 -0.401594199921614 0.688252448238614 -921.805237609323 322.87516642599 -2.85498958564415 0.00458658906999865 MX2 other 1 1 1 -0.401594199921614 -2.85498958564415 0.000249119467817482 177.589383321656 59.5148401845731 2.983951276201 0.00306590934990381 -305.23990727009 143.199176405568 -2.13157585771018 0.0338081066853725 EP400 other 1 1 1 2.983951276201 -2.13157585771018 0.105912013210302 22.4187765743483 10.9449810895887 2.04831569747288 0.0413498585296111 27.0786810094668 21.5788314213812 1.25487244794155 0.210446517433501 MEX3B other 1 1 1 2.04831569747288 1.25487244794155 0.000816412582091064 52.1956805480298 14.6935846503388 3.5522768466731 0.0004402977728437 -33.688557763425 48.2480231618032 -0.698237058344298 0.48554407795354 PI4KAP2 other 1 1 1 3.5522768466731 -0.698237058344298 0.259020351766558 -104.382294887022 63.5166249582258 -1.64338541217631 0.101300936048873 -96.3219251455361 116.873081386389 -0.824158343417765 0.41047318435147 FAM46C other 1 1 1 -1.64338541217631 -0.824158343417765 0.000641564365487558 40.7306496562097 14.346766718936 2.83901247257685 0.00481936454461539 -96.9461425005452 45.6250272273764 -2.12484569088376 0.0343777747303662 COA5 other 1 1 1 2.83901247257685 -2.12484569088376 4.86669940878867e-08 112.466003178647 27.5113560539434 4.08798472013257 5.51642189246474e-05 -229.39982122323 65.6804547683039 -3.4926649340731 0.000545945651047352 UTP11 other 0.000545654337713386 1 0.585844004979756 4.08798472013257 -3.4926649340731 8.08253182588398e-11 62.163245720102 43.3535982897824 1.43386588823822 0.152599288944656 -411.132234345864 70.3475609701763 -5.844299769258 1.26643254209773e-08 PSMG1 essential 1.01427691883018e-06 0.000192371103144645 1 1.43386588823822 -5.844299769258 2.04743587665972e-07 180.86173738345 41.7190427731864 4.33523219520495 1.95466758651718e-05 -307.688224717227 118.002407766378 -2.60747412312459 0.00955000998836698 PRR14L other 0.00222064895182513 1 0.214954794489294 4.33523219520495 -2.60747412312459 0.0041458463774623 10.3207665384166 4.69121144635699 2.20002160559856 0.0285243522392689 -23.0459421821112 12.1586723460143 -1.89543245563861 0.0589417579210233 SERHL2 other 1 1 1 2.20002160559856 -1.89543245563861 0.0644382994121977 28.8547001990655 13.0277969517601 2.21485645699807 0.0274761818879442 2.93978885043955 21.7886705785141 0.134922818711964 0.892757988797325 PCBP3 other 1 1 1 2.21485645699807 0.134922818711964 1.38001388704254e-23 240.41419064997 24.6076343230764 9.7699026039458 7.36515043792691e-20 -197.99592074602 74.5137320869356 -2.6571735866755 0.00828286369627118 SETD3 other 2.04504257920835e-19 1 1.09262006746646e-15 9.7699026039458 -2.6571735866755 1.12465749473779e-08 76.1153899223292 12.321012460636 6.17768954990573 1.99404712749091e-09 37.0631274431262 26.3889681260967 1.40449324376854 0.161151069711813 TNFAIP8L3 other 0.000130156611866004 1 2.63313923185175e-05 6.17768954990573 1.40449324376854 1.05739835331335e-08 101.528233076908 18.1247322080444 5.60164044971911 4.63186570909929e-08 -71.9944705164139 52.7598352976219 -1.36456966005083 0.17336234274099 ZNRF3 other 0.000122510173214884 1 0.000584448815174148 5.60164044971911 -1.36456966005083 0.0921383081364816 28.8593369103703 13.7422779042355 2.10004026344683 0.036530537671122 -35.8327763617117 84.2563327510186 -0.425282886066252 0.670924584807235 FBXL7 other 1 1 1 2.10004026344683 -0.425282886066252 5.43942988007268e-17 112.625891913776 12.4578403689281 9.04056309749186 1.71095780173049e-17 4.81196426749352 50.6479983142823 0.0950079850665409 0.924369669583045 TANGO2 other 7.66524458699842e-13 1 2.50552660485414e-13 9.04056309749186 0.0950079850665409 0.00357720731545747 26.3721734180396 10.5977590208315 2.48846698308588 0.0133475190266956 -54.5933245273949 36.4800026750668 -1.49652742664704 0.135520709659017 SMG1P5 other 1 1 1 2.48846698308588 -1.49652742664704 0.0346867883940466 28.7359098018345 24.5787570466183 1.16913600420604 0.243218986723536 -76.8649690994503 47.8463218837703 -1.60649692752084 0.109151046333842 SFXN4 other 1 1 1 1.16913600420604 -1.60649692752084 0.419522933773503 -2.42966024571516 4.79966602773724 -0.506214439020167 0.61305577819829 -13.9244274230245 10.6964140826167 -1.3017846275841 0.19392927844629 FAM167B other 1 1 1 -0.506214439020167 -1.3017846275841 0.00307438108525685 6.87127150315875 56.7575606375439 0.121063545120252 0.90371740379703 -301.534894112924 101.018268351719 -2.98495409823357 0.00305686033734312 MRPL54 essential 1 1 1 0.121063545120252 -2.98495409823357 0.000113949611344466 -5.76627585722811 7.98528942820447 -0.722112317790426 0.470761138705153 -71.6673665786473 17.4959230533278 -4.09623238283595 5.34489861639907e-05 ZNF438 other 0.975864471554007 0.770413686567762 1 -0.722112317790426 -4.09623238283595 9.35625898433936e-19 603.345402695561 63.6079427818315 9.48537833969842 5.71390815518641e-19 -97.1968329193023 255.226312886112 -0.380826066952877 0.703585006150513 HMCES other 1.3432781023816e-14 1 8.44115651765689e-15 9.48537833969842 -0.380826066952877 0.277357115815888 42.279992962579 28.3896220374826 1.48927635974713 0.137418301431791 -21.1920838450742 101.382211676113 -0.20903157955142 0.834559126487912 DGCR6 other 1 1 1 1.48927635974713 -0.20903157955142 0.41201494052406 2.29841585664573 1.98562483139846 1.1575277566543 0.247920062893594 4.81523830432355 3.84733873098178 1.25157638591775 0.21163839147999 RP1L1 other 1 1 1 1.1575277566543 1.25157638591775 0.0081526430477895 8.87336554465146 5.00949514280181 1.77130934190078 0.0774610293922807 -25.1801435593135 13.0179555782466 -1.93426251979154 0.0539622350111254 ZNF530 other 1 1 1 1.77130934190078 -1.93426251979154 0.0715132992863573 31.5179916317991 34.8468495829481 0.904471767434095 0.36642785191789 -181.591179093216 102.784663971157 -1.76671472257936 0.0782322595089157 NDUFB1 other 1 1 1 0.904471767434095 -1.76671472257936 0.00017910336393493 55.9464004829398 13.9884270333218 3.99947759313253 7.88944691255398e-05 -1.15638237269684 27.6180100873728 -0.0418705898447604 0.966627974245363 KLHL25 other 1 1 0.826419564090029 3.99947759313253 -0.0418705898447604 2.38282862747144e-13 65.2570917421523 8.17611178082115 7.98143341132237 2.67709641234441e-14 10.289974032795 48.11096886212 0.213880000261161 0.830778137757192 TRMT12 other 3.18059965194888e-09 1 3.83253122391226e-10 7.98143341132237 0.213880000261161 8.76426490755565e-13 25.9150464684016 3.41689289658669 7.58438945929193 3.89332121130076e-13 -20.7131133828996 19.9993555217562 -1.03568904309776 0.301151863013747 GUSBP1 other 1.15618182660474e-08 1 5.49269756490311e-09 7.58438945929193 -1.03568904309776 0.0325359250079267 -3.6870337814354 17.9110952885956 -0.205851943838578 0.837039539213945 -84.1551330547533 33.7640944603253 -2.49244454500743 0.0132002359986095 GPR1 other 1 1 1 -0.205851943838578 -2.49244454500743 0.00620874656043002 2.38534503616546 2.45264319344859 0.9725609670975 0.331510738792457 19.4973775277607 6.139806465882 3.17556874733834 0.0016419660951396 BMP8A other 1 1 1 0.9725609670975 3.17556874733834 4.35977709647081e-06 339.482261113921 75.1553949133046 4.51707108326063 8.84859951226362e-06 -205.068419203868 168.302030702819 -1.21845481214644 0.223954364350852 ALYREF essential 0.0429263652918516 1 0.0997679595007723 4.51707108326063 -1.21845481214644 4.37788692311629e-05 166.615934326872 41.6633928110843 3.99909664300179 7.92797847290946e-05 187.410424311532 79.2909876320433 2.36357787824798 0.0187062463011109 RFLNB other 0.393221803434305 1 0.830297185467808 3.99909664300179 2.36357787824798 0.861923159483568 -5.36612875864116 16.2490680093994 -0.330242248696177 0.741436452360162 -18.1682132405954 38.6364510940498 -0.470235042974571 0.638512501363154 NOG other 1 1 1 -0.330242248696177 -0.470235042974571 4.99518541766578e-08 1082.83682974531 182.023114517451 5.94889738380725 7.09589758989235e-09 1104.77481953142 1032.29434012809 1.07021299699689 0.285332529126724 UPP1 other 0.000559760477903627 1 9.21331343071623e-05 5.94889738380725 1.07021299699689 5.72448505940827e-05 30.2782911419607 13.3515426912664 2.26777473151223 0.024017787838693 -61.7856963420916 21.392696677056 -2.88816773662563 0.00414237181854435 TRIM52 other 0.507132131412978 1 1 2.26777473151223 -2.88816773662563 0.0056994187352897 116.696352789122 38.7653415339829 3.01032696143854 0.00281723843437822 15.2482456886398 102.77949018968 0.148358837551141 0.882153026307749 CMTM4 other 1 1 1 3.01032696143854 0.148358837551141 2.59143346550687e-11 344.475777957164 77.5182372743609 4.44380303357464 1.22083800562746e-05 -659.005179397208 152.053043587284 -4.33404793386406 1.96462748730927e-05 TMEM50A other 3.3007088050161e-07 0.286953490796392 0.136184479527743 4.44380303357464 -4.33404793386406 0.230499359021198 6.70353599372823 8.34338351199403 0.803455334888007 0.422345620720447 -55.0629073613085 39.609227433882 -1.39015353059392 0.165509385910274 NPBWR1 other 1 1 1 0.803455334888007 -1.39015353059392 0.413055396951128 2.72051179463549 16.7774883662478 0.162152506695132 0.871288098166764 -30.3738118812548 30.6607713195662 -0.990640827808258 0.322609461097739 ASCL2 other 1 1 1 0.162152506695132 -0.990640827808258 1.21995259286289e-05 73.0257246013609 16.9015870414983 4.32064305097869 2.08634582996716e-05 -112.590954270131 68.4913390473365 -1.643871412593 0.10119725989612 TBK1 other 0.115590508173759 1 0.229039045213795 4.32064305097869 -1.643871412593 0.0560631580071921 224.031304047363 121.349426010994 1.84616698580072 0.0657942478549262 -358.254580615678 328.554736026891 -1.09039542375172 0.27636194781337 CBX6 other 1 1 1 1.84616698580072 -1.09039542375172 0.151943530236844 -13.1820148794339 35.5641510529204 -0.370654563350006 0.711140072415736 -292.877064106996 150.429029292079 -1.94694511747686 0.0524159600869402 MACC1 other 1 1 1 -0.370654563350006 -1.94694511747686 5.44526776280864e-07 203.723345422083 53.4538155601423 3.81120305982402 0.000165940067144113 -414.12715058863 151.855085484509 -2.72712072346682 0.00674246781199282 TBL3 essential 0.00574366843621056 1 1 3.81120305982402 -2.72712072346682 0.623059378245601 21.238690567576 30.0037058876775 0.707868909496901 0.479543533515916 -43.5530570540683 94.0972105283292 -0.462851733962465 0.643786225359382 ACP7 other 1 1 1 0.707868909496901 -0.462851733962465 0.0655722199353597 -73.3911746924399 209.150400433071 -0.350901430456145 0.725896859892775 -1422.0829073861 608.822274040711 -2.33579316661303 0.0201292317239425 KREMEN1 other 1 1 1 -0.350901430456145 -2.33579316661303 1.19938292815302e-13 21.8427375116 15.9107629791933 1.37282778583051 0.170770192087554 -134.98811412752 22.4682422271367 -6.00795170191301 5.12248713502488e-09 TRAIP essential 1.60933201299572e-09 7.79693766822137e-05 1 1.37282778583051 -6.00795170191301 0.0124298025970545 46.1232179474975 18.562203834863 2.48479212693863 0.0134800181652368 -55.6619292881335 53.5031345016411 -1.04034894042378 0.298973138492501 CHEK2 ts 1 1 1 2.48479212693863 -1.04034894042378 0.00504826544396653 24.8178747730591 7.63224440615461 3.25171384095694 0.00127018528350098 -1.48024009920602 35.077462586254 -0.0421991783346978 0.96636640082518 FOXL2 other 1 1 1 3.25171384095694 -0.0421991783346978 0.000166433360468107 12.5855571908584 2.97678882087127 4.22789722355068 3.12667441585613e-05 12.3000715059287 12.3685033258938 0.994467251359197 0.320788940842961 AIFM3 other 1 1 0.338962773422963 4.22789722355068 0.994467251359197 0.188525738010995 -27.3684253337746 61.0111381579298 -0.448580802786047 0.65404055414633 -181.699910592468 100.178807735448 -1.81375596994826 0.0706607279312871 B3GALT5 other 1 1 1 -0.448580802786047 -1.81375596994826 0.000314238613480297 141.230239363382 73.068121457031 1.93285712766592 0.0542172871772105 -334.001938204809 167.270559106127 -1.99677659947855 0.0467743329778284 ZNF703 other 1 1 1 1.93285712766592 -1.99677659947855 0.14628409596251 21.1720483932496 11.2219936199552 1.88665660579249 0.0601116826594788 -22.6754816281369 36.0380223870173 -0.629209932349278 0.529660551082649 SLC35F3 other 1 1 1 1.88665660579249 -0.629209932349278 0.468724410903364 8.38366762797629 8.40885906999053 0.99700417835469 0.319527731197387 26.850724227784 27.4811706984639 0.9770589660245 0.329289717126091 TUBA8 other 1 1 1 0.99700417835469 0.9770589660245 0.0580071637399337 38.9378176693466 16.8412495492584 2.31205039480347 0.0214134226438247 87.5825048260074 76.7362870071474 1.14134405301432 0.254585523408024 EMILIN3 other 1 1 1 2.31205039480347 1.14134405301432 0.120067054917765 -8.86060047670857 10.3818706972797 -0.853468583367184 0.394037899606373 25.6502046031516 20.711186346244 1.23847104527661 0.216449195082598 OLFML1 other 1 1 1 -0.853468583367184 1.23847104527661 0.975028922111648 1.99347329119336 13.2983416017174 0.149903901621531 0.880934870314025 12.2047927753383 67.4015513699572 0.181075843615943 0.856422677648607 RBM12B other 1 1 1 0.149903901621531 0.181075843615943 0.262476251296063 -8.94921964959513 9.15509440164642 -0.977512547329466 0.329053869307917 -22.1861609594501 13.6247461609111 -1.62837242598334 0.104430020481871 CCR4 other 1 1 1 -0.977512547329466 -1.62837242598334 0.196215068050309 17.2560586427333 10.9318210398095 1.57851638623549 0.115434999935768 31.2890359043975 37.472201553455 0.834993264534055 0.40434445411726 LIN9 other 1 1 1 1.57851638623549 0.834993264534055 0.296084818573937 25.329033568583 16.8929751389774 1.49938263450948 0.134760284859853 4.38944056907904 39.0816677105256 0.112314566553076 0.910644412977535 BTBD9 other 1 1 1 1.49938263450948 0.112314566553076 0.0132010197161576 61.0002557544759 29.4297675707062 2.07273997689314 0.0390068631515842 -122.572085027881 87.0748115399635 -1.40766408631991 0.16021348566743 NUDT14 other 1 1 1 2.07273997689314 -1.40766408631991 0.443167975915693 -3.32926017862169 5.17747127304233 -0.643028228076558 0.520669169577128 19.8301515810664 20.3679443709535 0.973596118484395 0.330997109701994 MAATS1 other 1 1 1 -0.643028228076558 0.973596118484395 0.047111894182053 91.7985541543748 62.6079747765599 1.4662437889421 0.143566927089882 -290.608016987066 164.39934932884 -1.7676956640855 0.0780677195206458 GPR39 other 1 1 1 1.4662437889421 -1.7676956640855 0.016475295871814 -5.17059342345698 86.450229043884 -0.0598100604317922 0.952344481835502 -377.493742369949 140.930516879195 -2.6785805567827 0.00777784598646652 FAM3B other 1 1 1 -0.0598100604317922 -2.6785805567827 0.03645496992032 102.547868338195 44.6670661062866 2.29582726777218 0.0223319676708658 170.027007994939 149.734660526464 1.13552204544444 0.257006408260294 IQGAP3 other 1 1 1 2.29582726777218 1.13552204544444 3.29987053266223e-08 254.477034338218 52.4299706460907 4.85365586137691 1.9028549610483e-06 -326.344227930699 136.990154694879 -2.38224585305105 0.0177949283274651 TOB2 other 0.000373578343002691 1 0.0223261972579797 4.85365586137691 -2.38224585305105 0.0256003806121851 35.6571127281449 14.5919359981998 2.44361767571788 0.0150806990676503 48.4610779041639 20.9020691834296 2.31848232243831 0.0210529863712484 SCN5A other 1 1 1 2.44361767571788 2.31848232243831 2.86186426578529e-05 400.036896941423 94.5451604518429 4.23117264838938 3.03962813511402e-05 -55.4257708771921 136.881094668503 -0.404919108890981 0.685807515864865 ARSI other 0.262146766745933 1 0.329860445222573 4.23117264838938 -0.404919108890981 0.0513510445185689 8.53370149725869 6.0172798239795 1.41819921075483 0.157111821795546 -32.9228738627462 19.5147316565599 -1.68707796971829 0.0925689776231132 TTC32 other 1 1 1 1.41819921075483 -1.68707796971829 0.8493830673638 9.61112321032467 22.5186475843555 0.4268073015629 0.669809405026666 -30.1991278483565 99.1690237088018 -0.304521782295979 0.760930217169983 LRRC55 other 1 1 1 0.4268073015629 -0.304521782295979 0.0409282366941681 43.4740371310088 17.1247820261143 2.53866221857384 0.0116026976070871 7.01301150976143 32.7392376917578 0.214208149126422 0.83052159908909 DNAH2 other 1 1 1 2.53866221857384 0.214208149126422 1.16571446766429e-05 17.0277343001342 3.71386148815903 4.58491366854257 6.52331356531761e-06 -7.83115950334644 14.3655605697719 -0.545134278980022 0.586040903855735 HTR7P1 other 0.110579674402635 1 0.0741765985512266 4.58491366854257 -0.545134278980022 0.00333840266866064 101.949152542373 39.7883717628705 2.56228511058373 0.0108574720955927 -186.872881355932 102.569115122082 -1.82192155146807 0.0694031809060989 KMT5A other 1 1 1 2.56228511058373 -1.82192155146807 0.878019244806327 -2.31216681224836 4.91155168038648 -0.470760965721208 0.638132170292724 -3.09527900922537 7.82811429482655 -0.395405444101778 0.692807153309055 KCNH8 other 1 1 1 -0.470760965721208 -0.395405444101778 1.76326625192214e-05 529.966965663187 114.491174055741 4.62888925748259 5.36866772723005e-06 -11.8349647747931 321.517978616642 -0.0368096515962001 0.970659947240793 SMTN other 0.16463616994197 1 0.0613799781254212 4.62888925748259 -0.0368096515962001 0.458591642441712 34.4585050865739 30.6525040136933 1.12416607371393 0.261787792359861 -18.1987215681899 87.0796325488961 -0.208989416187202 0.834589889553916 NPW other 1 1 1 1.12416607371393 -0.208989416187202 5.50875006951823e-15 14.6408172921516 3.00202624463374 4.8769784469149 1.70043181715633e-06 -17.5983036713968 4.5936573355029 -3.8310005266142 0.0001535939862531 PP2D1 other 7.57398047058062e-11 1 0.0200225846470158 4.8769784469149 -3.8310005266142 0.615935302196889 46.9645954206504 55.5417802254676 0.84557238226793 0.398423146187639 -59.5631844595072 136.080074356228 -0.43770687766957 0.661894065235457 COA3 other 1 1 1 0.84557238226793 -0.43770687766957 0.274849952344865 10.7408040132772 6.68387128077237 1.60697349815451 0.109052619137316 3.87262434857305 14.9677759102706 0.258730780831354 0.79601035674372 NPB other 1 1 1 1.60697349815451 0.258730780831354 0.862083319873066 -1.30991099506287 2.40993764181137 -0.543545597336829 0.587132656835872 -1.05138754396245 5.0460082018092 -0.208360252681612 0.835080244757341 ST6GALNAC3 other 1 1 1 -0.543545597336829 -0.208360252681612 1.91850745931314e-07 263.425976997405 89.4039884154577 2.9464678440661 0.00345171010819911 -779.359236787809 191.197685961873 -4.07619596893669 5.78882014900205e-05 PTP4A2 other 0.00208406747065236 0.833069107642885 1 2.9464678440661 -4.07619596893669 4.94196291392651e-12 10330.29851577 2356.7013089733 4.38337199391227 1.58685074253224e-05 -26424.9029772948 5435.62205584622 -4.86143125953244 1.82962491094349e-06 ACTG1 other 6.4087375067799e-08 0.02732361842003 0.175585034661192 4.38337199391227 -4.86143125953244 0.0748233305508127 0.464875386450525 94.1117727031142 0.00493960928689575 0.99606187531363 -321.638548032491 153.160737362203 -2.1000065262931 0.0365157618331287 TMPRSS2 other 1 1 1 0.00493960928689575 -2.1000065262931 3.50439178188379e-06 244.250058561724 65.1953922473468 3.74643130660302 0.000212939135369965 -162.689911875451 131.83326888255 -1.2340580890882 0.218092489701688 DENND5A other 0.034760325987884 1 1 3.74643130660302 -1.2340580890882 0.00319963067411355 128.858512585275 37.6751586464466 3.420251359643 0.000706721729978639 55.4512325671511 98.3651182944853 0.563728621777705 0.573333670272148 DIABLO other 1 1 1 3.420251359643 0.563728621777705 9.74194726780576e-08 49.7588455633727 11.021393008905 4.51475104128571 8.93085047271539e-06 -49.5921576306137 22.936830314456 -2.16211904394472 0.0313521281261041 VPS33B other 0.00107638775361986 1 0.100659615677975 4.51475104128571 -2.16211904394472 6.90750431249536e-11 191.37392134871 27.433297214905 6.97597229562084 1.81463005502465e-11 14.4477155246141 111.810229406831 0.129216401766289 0.897269411576424 TBX1 other 8.69102192598167e-07 1 2.49801973374693e-07 6.97597229562084 0.129216401766289 0.805163128664891 5.58122815041397 21.3596404547939 0.261297851067588 0.794034125152771 32.9362908436453 51.9311737143979 0.634229663761937 0.52639272543153 ADAP2 other 1 1 1 0.261297851067588 0.634229663761937 0.00170355332200807 228.343896211504 66.2229886387657 3.44810617740431 0.000640798978820137 -39.2864243298401 184.781651335142 -0.212609986142973 0.831767832380708 UQCR10 other 1 1 1 3.44810617740431 -0.212609986142973 4.59329484753253e-07 816.968054626388 185.908585338926 4.39446114409935 1.51519308538051e-05 -1285.86530628648 660.091853006082 -1.94800966021715 0.0522933837364218 EIF3C other 0.00486751454993023 1 0.167898545791014 4.39446114409935 -1.94800966021715 0.475509402298536 17.8142587120305 26.3311005345878 0.676548201569858 0.499187554555088 118.016380756192 103.587284098514 1.13929409177245 0.255443400641148 CLDN5 other 1 1 1 0.676548201569858 1.13929409177245 2.28402728914283e-08 299.236987907732 57.458197683902 5.20790766104326 3.4374492143347e-07 -296.793513688953 160.348739037999 -1.85092514895686 0.0651074661986205 NIPSNAP1 other 0.000260744555328545 1 0.0041840631836882 5.20790766104326 -1.85092514895686 0.555849923963383 -9.40089684682552 10.5780801440548 -0.888714844168499 0.374823900517259 -22.869920368002 35.9234981818744 -0.636628433350662 0.524822028437348 CNTN2 other 1 1 1 -0.888714844168499 -0.636628433350662 0.697105587800895 -36.5921624012385 64.3866290771045 -0.568319275690276 0.570216774641759 -161.363184629715 259.169729592437 -0.622615862135869 0.533980405334238 SPRR4 other 1 1 1 -0.568319275690276 -0.622615862135869 1.36229888681231e-18 191.006558869354 21.4735717850334 8.89495985025096 6.16642842131558e-17 -16.2780325266307 88.9504380742815 -0.183001150742361 0.854923679536081 LRTOMT other 1.95340037380017e-14 1 9.00236885227862e-13 8.89495985025096 -0.183001150742361 0.153413622695889 16.0926705335315 8.28836558581574 1.9415975763752 0.0530688639263556 11.197607177668 46.8616087592545 0.23895054980281 0.811297848879057 KCNQ3 other 1 1 1 1.9415975763752 0.23895054980281 0.000815291375642563 56.3188555284658 15.5586380849751 3.61978055025604 0.000342626269646661 87.3016613851285 28.7388687885625 3.03775566211127 0.00257962844768977 ADRA2C other 1 1 1 3.61978055025604 3.03775566211127 5.84380821815159e-05 110.972973664378 47.8486795406119 2.31924840413179 0.0210128638967886 -336.166279147203 113.286591676332 -2.96739688406952 0.00323041895620846 NR2C2AP essential 0.517177027306416 1 1 2.31924840413179 -2.96739688406952 0.0852366729190428 78.0746196639898 40.2519234129187 1.93964941409314 0.0533148075458467 -46.0406212925398 91.3060388406557 -0.504245084740653 0.61444167306127 C1QTNF12 other 1 1 1 1.93964941409314 -0.504245084740653 3.09920442582961e-08 287.764824012622 50.1123166635713 5.74239714249351 2.18110054004143e-08 -54.2348860298735 141.555937858591 -0.38313395291162 0.701876434175412 CRELD2 other 0.000351387797800561 1 0.000278657404995693 5.74239714249351 -0.38313395291162 2.64684777934209e-09 81.8014315497101 17.4030676692433 4.70040300390711 3.95213390258533e-06 -87.1454993626658 37.2239142315518 -2.34111595090662 0.019876469092019 SCFD2 other 3.15080759652882e-05 1 0.0455443910933934 4.70040300390711 -2.34111595090662 1.29945351733338e-13 96.0566359882146 41.2756161189318 2.32720053678754 0.0205801257493426 -437.923271269042 74.7767324095658 -5.85641090694437 1.17636418508626e-08 UBE2F other 1.74243722139233e-09 0.000178736774282006 1 2.32720053678754 -5.85641090694437 0.0295968744890649 52.3797204408484 20.3217469911042 2.57752054800099 0.0103983963324217 -18.3064436258586 37.5698577836103 -0.487264118253989 0.626404790116981 KCNJ12 other 1 1 1 2.57752054800099 -0.487264118253989 3.62881611077271e-33 333.169922530016 24.1637452217748 13.7880084180736 2.8774584224799e-34 77.3347497252563 150.71424242333 0.513121709546443 0.608220239350362 PPP1R2 essential 5.50709132970866e-29 1 4.38524663585936e-30 13.7880084180736 0.513121709546443 0.0751510263230437 47.1233727727107 24.938247074973 1.88960245004557 0.0597149038164462 -48.7978158481793 70.8633483663808 -0.688618545032372 0.491562276902988 PGP other 1 1 1 1.88960245004557 -0.688618545032372 0.288712390346531 1.15397569618561 20.5342314609826 0.0561976569894177 0.955219529623067 -81.464641905972 53.4535695949597 -1.52402622543759 0.128492890472557 C22orf46 other 1 1 1 0.0561976569894177 -1.52402622543759 0.173282287417194 26.1438771830406 20.1695499355208 1.29620528304394 0.195841735704561 80.2144435441946 51.9944093622738 1.54275131745985 0.123882520051754 SNRNP35 essential 1 1 1 1.29620528304394 1.54275131745985 2.11683290468427e-11 161.011567567568 23.6206211639636 6.81656788150907 4.73572586663805e-11 -67.1936131425544 98.1001394401964 -0.684949211346604 0.493878066253621 CMSS1 other 2.70129046966759e-07 1 6.46900153382758e-07 6.81656788150907 -0.684949211346604 0.276106973312333 4.86973254416898 3.69340136706724 1.318495354334 0.188317476030532 9.44563982255185 6.99742215086026 1.34987422780982 0.178047546706611 PCDH9 other 1 1 1 1.318495354334 1.34987422780982 0.000229408095059437 28.1302433110335 7.09100918222242 3.96702959877103 8.98568734001917e-05 -5.56425872645588 21.9979981301486 -0.252943867598115 0.800474001251285 ACOT1 other 1 1 0.936039050209797 3.96702959877103 -0.252943867598115 1.73914127379503e-06 203.728452425978 54.4830480671092 3.73929983093157 0.000218693696948476 -53.0171798740146 102.6524835244 -0.516472452041676 0.605882313926139 OAF other 0.0176609796353885 1 1 3.73929983093157 -0.516472452041676 0.00633555878987956 455.92351138036 152.575963429923 2.98817389797942 0.00302432077062109 -86.6338419229838 337.785043487402 -0.256476251963521 0.797748441355088 ALDH1A3 other 1 1 1 2.98817389797942 -0.256476251963521 0.0139314891254159 5.84738693995744 1.98655401121495 2.94348248622812 0.00348736918142671 -0.308888691164701 8.22660495160314 -0.0375475293856801 0.970072303505112 HIST2H2AC other 1 1 1 2.94348248622812 -0.0375475293856801 0.768731531938549 2.89664558916069 6.30933576975388 0.459104681517637 0.646471669049146 -7.83603617192271 17.2051632529283 -0.455446778198343 0.649097692471712 POU6F1 other 1 1 1 0.459104681517637 -0.455446778198343 1.29767334951701e-08 107.088175037804 21.8780276060932 4.89478196873556 1.56546402744312e-06 -108.56030621265 48.4353520712779 -2.24134442241467 0.0256911994341146 TM2D3 other 0.000149764481267758 1 0.0184693445957739 4.89478196873556 -2.24134442241467 0.00255742807202137 111.243614461987 56.5621191344854 1.9667511784254 0.0500757257034477 -132.348911184329 104.433334494119 -1.26730523185374 0.205967642934666 TSSC4 other 1 1 1 1.9667511784254 -1.26730523185374 0.0620211563522626 -135.30672505154 1265.64537017924 -0.106907296656391 0.914929725854975 -7034.14491370798 3032.810819468 -2.31934839738599 0.021007373398986 TACSTD2 other 1 1 1 -0.106907296656391 -2.31934839738599 0.308723025228152 -4.94818322598352 6.71448526733933 -0.736941556794015 0.461709911245884 20.706291406464 18.4835028894308 1.12025796897536 0.263462687737052 PRKD1 other 1 1 1 -0.736941556794015 1.12025796897536 0.0488708688811927 4.86534574785735 5.13214637617887 0.948013831101955 0.343837772302228 23.8865840690486 9.67796802090551 2.4681404213623 0.0141042068792751 CCSER1 other 1 1 1 0.948013831101955 2.4681404213623 1.57437954771335e-07 66.379523809524 12.2029151612577 5.43964478424536 1.06245550497165e-07 -27.1843236117977 50.5036109641232 -0.538264949631204 0.5907683361425 ZDHHC23 other 0.0017185927142839 1 0.00132158840263424 5.43964478424536 -0.538264949631204 0.0414235566796286 -17.2887646161667 8.29391151435665 -2.08451278823509 0.0379086946688911 -37.6704611598623 19.8743385541629 -1.89543219550176 0.0589389482176179 MROH7 other 1 1 1 -2.08451278823509 -1.89543219550176 0.298405241635839 -597.92116256232 653.232197663925 -0.915327145080406 0.360711296204346 -2926.7710171476 2386.917038816 -1.22617207450134 0.221038288038496 S100A7A other 1 1 1 -0.915327145080406 -1.22617207450134 0.512325863988631 -46.1416040376435 94.4646553474802 -0.488453632397382 0.625563112621046 -158.808112346142 137.476646264112 -1.15516428907532 0.24888499000912 SLIT3 other 1 1 1 -0.488453632397382 -1.15516428907532 1.022718191427e-05 142.504741656642 35.1356810574795 4.0558411668046 6.28076894063573e-05 -47.387264886417 49.8738499241147 -0.950142508719877 0.342756886512176 EFNA5 other 0.0975366339163929 1 0.664442546229854 4.0558411668046 -0.950142508719877 6.19719997639886e-13 1390.14075017841 471.161357281388 2.95045578058344 0.00340714984224561 -3649.55357385535 888.797413879164 -4.10617033405491 5.1125505726683e-05 PKP3 other 8.19889556877569e-09 0.737383169095949 1 2.95045578058344 -4.10617033405491 0.191229713916749 -32.9432038166757 80.3589479179486 -0.409950661005576 0.682116448621064 -265.800000878609 149.268060356702 -1.78068905192065 0.0759118659775147 CSF1 other 1 1 1 -0.409950661005576 -1.78068905192065 3.14327544580676e-05 10.4350050355163 2.29485071339268 4.54713893789165 7.75777083049494e-06 12.5348961039396 16.4128848766625 0.763722904177739 0.44560222397248 ACTRT3 other 0.286540989639744 1 0.0877791769470502 4.54713893789165 0.763722904177739 0.0962966220127348 20.1130455032796 17.3378682734715 1.16006450078147 0.246895499724493 -72.7708479017833 47.6778553081542 -1.52630288068636 0.127931541172381 PLA2G6 other 1 1 1 1.16006450078147 -1.52630288068636 2.75318582830202e-08 117.222831881892 28.6238864594966 4.09528007483417 5.36579625914161e-05 -80.0996455250703 66.7102253693299 -1.20071016222194 0.230765777125314 MAML2 other 0.000312927101244807 1 0.570598774197118 4.09528007483417 -1.20071016222194 2.73403484042728e-08 61.4884541553478 10.8806213946537 5.65118957135673 3.52640906901635e-08 -44.4708766853913 49.5153009672857 -0.898123929707562 0.369794732154593 SS18L1 other 0.000310805080659773 1 0.000446796029044372 5.65118957135673 -0.898123929707562 0.324822555243529 3.78855048969676 2.8231673807767 1.34195036238144 0.180572481599024 -0.317171292791491 7.37200118600703 -0.0430237712649208 0.965709671504563 KCND2 other 1 1 1 1.34195036238144 -0.0430237712649208 4.59728730862191e-13 322.732941420991 41.0128241386038 7.86907383725411 5.56374675173173e-14 265.231277008411 202.134561294636 1.31215204025304 0.190409288764761 TOP1MT other 6.0978418861561e-09 1 7.94280486277221e-10 7.86907383725411 1.31215204025304 7.03050013105183e-22 1095.93517390195 103.65546499218 10.5728643828344 1.37381342047195e-22 -110.787396295842 476.395998559994 -0.232553162979369 0.816257999203094 COPB2 essential 1.0327101642502e-17 1 2.05838464789312e-18 10.5728643828344 -0.232553162979369 0.000220229079507993 91.172591472144 22.8171353980741 3.9957948218092 8.10775683429094e-05 -35.6186847346872 94.7759576113776 -0.37581983482287 0.707314691376759 THAP7 other 1 1 0.848152442435175 3.9957948218092 -0.37581983482287 0.424107067959475 -54.0096666486251 48.7875655050839 -1.10703754305996 0.269109166446005 -111.290010475156 127.378220148786 -0.873697327103189 0.38293829081172 KNTC1 other 1 1 1 -1.10703754305996 -0.873697327103189 0.387825807280109 2.81729925307635 3.26848703721922 0.86195821522158 0.389355970969728 -8.30187294606536 8.27749681117956 -1.0029448679283 0.31664525069805 CCR10 other 1 1 1 0.86195821522158 -1.0029448679283 0.91855730002575 4.1922313751428 11.8278970007008 0.354435904784629 0.723246412293852 -2.45963452697864 23.0432200809344 -0.106740052750427 0.915062301684187 NCMAP other 1 1 1 0.354435904784629 -0.106740052750427 0.120183289360665 13.4093393899507 13.0941679333117 1.0240696055102 0.30657591786556 -55.1154126531771 36.4108498377242 -1.51370849345223 0.131086815699142 BPIFC other 1 1 1 1.0240696055102 -1.51370849345223 0.0117448552795488 23.5518569281918 12.4420206541771 1.89292861527962 0.0592780693969232 -52.0866564373362 28.745606039111 -1.81198672125638 0.0709343593559272 WDR27 other 1 1 1 1.89292861527962 -1.81198672125638 1.2684094150914e-08 98.5532837851817 16.1787391347125 6.09153055529088 3.27768116053467e-09 1.52881816531271 65.9197900389023 0.0231920970077497 0.981511820676032 TXNRD2 other 0.000146463235160604 1 4.30195652320175e-05 6.09153055529088 0.0231920970077497 0.0624556447573477 94.675715016121 41.7258787442396 2.2689927178392 0.0239342731214371 -92.7387308659494 211.37653068583 -0.438737122636322 0.6611480926754 PTP4A3 other 1 1 1 2.2689927178392 -0.438737122636322 0.027910042294678 7.48105856112863 4.13781045824202 1.8079751686613 0.0715670760348849 23.9100554490867 10.1462179789891 2.35654856800829 0.0190595934411624 TMEM255B other 1 1 1 1.8079751686613 2.35654856800829 0.00147038922160361 129.754344813935 39.925168608731 3.24993855594037 0.00128419139734688 -121.747003217817 159.337416011593 -0.764082952173382 0.445412401211516 PROS1 other 1 1 1 3.24993855594037 -0.764082952173382 0.00193549495096075 45.4512698008366 13.2570044703503 3.42847208828283 0.000686401432871317 -23.832697735537 34.2042271775442 -0.696776384153584 0.486448588646174 GAST other 1 1 1 3.42847208828283 -0.696776384153584 0.0116053009102564 38.3264287268426 15.6769675310906 2.44476035628916 0.0150339019531225 -30.993056034643 32.4283443637186 -0.955739697562808 0.339925208326067 HDDC3 other 1 1 1 2.44476035628916 -0.955739697562808 2.62841381237036e-08 35.7291364308105 6.57077344590845 5.43758458953697 1.07594200264774e-07 -1.28031703744932 17.2149414720339 -0.074372430456951 0.940760660196731 ZFP1 other 0.00029913977598587 1 0.00133814906869299 5.43758458953697 -0.074372430456951 0.289638935205126 -22.1817936761155 19.1215555908497 -1.16004127230789 0.246896765497248 -55.5866241261498 35.9600568476493 -1.54578799365228 0.123144129133241 CEND1 other 1 1 1 -1.16004127230789 -1.54578799365228 0.594458465007128 -174.367213297138 219.176178323743 -0.795557321195655 0.426884676798493 -416.465064601783 515.952966787224 -0.807176412212647 0.420170064956682 C6orf58 other 1 1 1 -0.795557321195655 -0.807176412212647 0.333390249205698 16.3971580850191 12.6833210372446 1.29281266608871 0.197011407847387 18.8188748962746 23.5634315567524 0.798647465711833 0.425089045007295 DHRS7C other 1 1 1 1.29281266608871 0.798647465711833 0.036295580020364 -20.0812872985289 17.5352695277794 -1.14519410532676 0.25298452028979 -84.0649992951451 32.8798557661909 -2.55673260530498 0.0110272272532508 DUSP8 other 1 1 1 -1.14519410532676 -2.55673260530498 0.605296607514111 91.7382535457771 193.582383669254 0.473897737009567 0.635896001609491 -352.337165355245 456.294054739208 -0.772171282303079 0.440582879877159 SOCS3 other 1 1 1 0.473897737009567 -0.772171282303079 3.65862356140556e-07 419.652472987194 78.1562011452855 5.36940724904346 1.62901020796238e-07 43.6751209655088 148.14995238772 0.294803476218524 0.768356403189063 SLITRK6 other 0.00390997100007413 1 0.00201085020070876 5.36940724904346 0.294803476218524 1.84583924958717e-05 73.2209252614423 17.5388558380791 4.17478346007442 3.85510474210243e-05 -158.98348838399 96.8592199615169 -1.64138724684295 0.101705646494215 LPAR5 other 0.171976842884037 1 0.415337687195458 4.17478346007442 -1.64138724684295 1.642405204878e-06 505.70169174178 99.8697232527632 5.06361362854571 7.00304033648032e-07 -338.85863923271 404.708212256872 -0.837291235932799 0.403061668140537 XPOT other 0.0167164001752483 1 0.00840084718764179 5.06361362854571 -0.837291235932799 0.000318571785679827 73.9018930196249 141.794467765312 0.521190242357987 0.602594738105263 -754.774210030418 208.201301335132 -3.62521370034807 0.0003357824846774 TMEM173 other 1 1 1 0.521190242357987 -3.62521370034807 0.911035822980386 -23.0081320772555 63.0598039853664 -0.3648620931742 0.715455364149063 18.3863361888875 146.810695273354 0.12523839734328 0.900413460739415 PDE4B other 1 1 1 -0.3648620931742 0.12523839734328 1.02874485826589e-05 129.487006593347 41.4200974291593 3.12618788052849 0.00193332038999981 -385.326595861703 134.396992559443 -2.86707751805738 0.00441753983066122 SNN other 0.0980908222356522 1 1 3.12618788052849 -2.86707751805738 0.00486560654393509 595.46461066441 209.517470179459 2.84207617700984 0.00477445683601648 -613.131567990387 567.477437154227 -1.08045100623754 0.280767917021786 NELL2 other 1 1 1 2.84207617700984 -1.08045100623754 0.00112451635882815 8.97534528469022 2.42797729844154 3.69663476279258 0.000257098154851005 -1.56323876879916 4.58497373930637 -0.340948249146494 0.73336698505877 KRBA2 other 1 1 1 3.69663476279258 -0.340948249146494 0.0323468602277591 11.4733681070342 6.46618074217027 1.77436551258284 0.0769594319458402 -18.7324605894722 14.7688583325709 -1.26837567045789 0.205591578858274 ZNF93 other 1 1 1 1.77436551258284 -1.26837567045789 2.90106657817984e-14 1975.23196749692 268.363964264924 7.36027272852105 1.56072519720721e-12 -1525.97154507481 646.350054243301 -2.36090572756477 0.0188295853894699 SEPT9 other 3.93674734659005e-10 1 2.18532742112953e-08 7.36027272852105 -2.36090572756477 1.88030466621712e-19 77.8335493495173 23.2096301381968 3.35350235596492 0.000893753781465021 -223.430056684729 42.6751293928761 -5.23560349701076 2.98447834604135e-07 CDCA2 other 2.71572402941738e-15 0.00449760886748431 1 3.35350235596492 -5.23560349701076 0.327071961964524 -25.5018058253086 23.4222932699462 -1.08878347356493 0.277071239534147 -68.1958311587156 48.5719555530298 -1.40401658492545 0.161286707188202 OR7E14P other 1 1 1 -1.08878347356493 -1.40401658492545 0.0124503120089868 3.58177712429977 28.789051560835 0.124414557969408 0.901065407886275 -156.450758981124 55.6603170346639 -2.81081329241603 0.00524716439464693 ZBTB40 other 1 1 1 0.124414557969408 -2.81081329241603 0.00585082203162505 135.975407064685 42.9223603854725 3.16793871174678 0.00168625143139227 103.216513924727 177.747647679444 0.580691307436435 0.561865043763649 HIST2H2BE other 1 1 1 3.16793871174678 0.580691307436435 0.752787657368849 11.2394479445618 15.1802277516422 0.740400482024778 0.459601620347505 3.02543997311425 43.6191097503477 0.0693604246035795 0.944746187573736 CLDN6 other 1 1 1 0.740400482024778 0.0693604246035795 2.43296489060112e-08 70.1774332879496 14.561655502096 4.81933069202527 2.23764242793329e-06 -104.959091098998 41.3124955011299 -2.54061367694739 0.0115424642610392 EIF4ENIF1 other 0.000277333667879622 1 0.026162515267396 4.81933069202527 -2.54061367694739 0.0585341480802986 6.13425315053389 9.75150972155404 0.62905676410035 0.529760690583347 -37.1272057374199 19.7438321481584 -1.88044577460019 0.0609554250913143 SERINC4 other 1 1 1 0.62905676410035 -1.88044577460019 0.0399442078419557 17.2926331572316 8.73420487951535 1.97987491658097 0.0485794285464248 -11.0942380042742 17.5472581879383 -0.63224908902863 0.527678427017222 RNLS other 1 1 1 1.97987491658097 -0.63224908902863 0.211620936080663 -27.7819187790622 22.0537704493525 -1.25973555600684 0.20868852436779 -121.282334836024 78.3046903140291 -1.54885147172717 0.122412031923594 APOBR other 1 1 1 -1.25973555600684 -1.54885147172717 0.0082841758438659 148.919089245783 66.9016880351622 2.22593918956894 0.0267300945410701 -332.215523052395 207.418009767381 -1.60167153963619 0.110236977323032 FAM110C other 1 1 1 2.22593918956894 -1.60167153963619 3.42506919867921e-14 593.608851917144 88.7213539484609 6.69071002074627 1.02447221081155e-10 -920.519443399271 338.546202638038 -2.71903638624905 0.00691254236078727 ATL3 other 4.63994124345073e-10 1 1.39174549838749e-06 6.69071002074627 -2.71903638624905 0.128600481619039 50.5017747501016 36.7374240310179 1.37466836835 0.170196115180063 -110.951688295374 89.4091185652111 -1.24094376586937 0.21553548951518 NDUFA12 other 1 1 1 1.37466836835 -1.24094376586937 0.0679100452783973 4.7633095036914 2.80362661268677 1.69898141290884 0.0903037859929222 -7.39877057584099 6.47740012085613 -1.1422438691132 0.254214681417444 TCTE3 other 1 1 1 1.69898141290884 -1.1422438691132 1.13834013124541e-09 190.478159374008 58.9680994151963 3.23018990374516 0.00136563298309494 -398.851123312232 98.5817142311374 -4.04589356578923 6.53992180727997e-05 UBE2G2 other 1.37192752617697e-05 0.939721364488059 1 3.23018990374516 -4.04589356578923 0.896202005705218 11.6009240306271 30.448215998197 0.381005049074601 0.703454715790408 30.1280888738855 84.9594943992364 0.354617092379451 0.723112260207686 OSBP2 other 1 1 1 0.381005049074601 0.354617092379451 0.143842526582266 -2.43980389727614 8.59961385139601 -0.283710866491997 0.776817173332805 -26.6601422983664 13.9526685937238 -1.91075578978194 0.0569378530431187 B3GALT5-AS1 other 1 1 1 -0.283710866491997 -1.91075578978194 8.83648168392812e-06 577.358615833417 173.600285521891 3.32579300833357 0.000985178349360903 -269.120913388995 279.738522629625 -0.962044522360305 0.336760496916094 ZBTB7C other 0.0847418593488707 1 1 3.32579300833357 -0.962044522360305 0.157016653532509 1.77628225007376 8.97570884074089 0.197898826888322 0.843249876485471 -22.7024824331171 13.4489475913409 -1.68804899260178 0.0923761109837055 PRR16 other 1 1 1 0.197898826888322 -1.68804899260178 2.74435904066769e-12 1238.46825390559 187.414687509786 6.60817073817081 1.62598151127552e-10 -369.902718739238 284.784650243867 -1.29888573145527 0.194918290925309 TMED9 other 3.5775464454144e-08 1 2.20027818105804e-06 6.60817073817081 -1.29888573145527 3.69820954602219e-06 49.1386807517504 10.6760917512828 4.60268438081247 6.04919936716628e-06 -33.9629038201695 34.1082277384169 -0.995739329543536 0.320138674349061 TMEM186 other 0.0366233691342577 1 0.0689185283901254 4.60268438081247 -0.995739329543536 0.0173937590443298 -31.3899864124209 26.5574576721694 -1.18196503595733 0.238097143749788 -193.89230953217 67.8061248117559 -2.8595102591463 0.00452158101261679 SDR42E1 other 1 1 1 -1.18196503595733 -2.8595102591463 2.48883265409786e-10 121.201183345508 33.9251974573872 3.57260067528706 0.000408175578063916 -257.824531775018 76.7696471361166 -3.35841756987474 0.000879161711687789 RBM33 other 3.07793934332282e-06 1 1 3.57260067528706 -3.35841756987474 1.01631387500311e-15 287.076391894552 37.9101849747937 7.57253999381505 4.06223746320506e-13 -225.570965900478 112.166098634469 -2.01104405561593 0.0451697657156108 BTBD6 other 1.41226976070432e-11 1 5.72694237562649e-09 7.57253999381505 -2.01104405561593 6.62142314211412e-08 746.830201585745 132.323913345623 5.64395491867794 3.66390763550235e-08 -338.550229801085 530.948542475286 -0.637632845214645 0.524168679175625 H1FX other 0.000736964395717302 1 0.000463923984807308 5.64395491867794 -0.637632845214645 0.236418228777459 -0.953786744684216 7.01379087907916 -0.135987337108836 0.891917606709947 -31.0653325975616 18.3335837751696 -1.69444954017312 0.0911620115403947 RBM43 other 1 1 1 -0.135987337108836 -1.69444954017312 1.26038101528754e-13 499.817823594228 114.816625260749 4.35318336921277 1.80785694084312e-05 -870.862255588551 191.948186437935 -4.5369652704176 8.08305383348522e-06 SUMO3 other 1.69042301770365e-09 0.119241210151574 0.199316227727954 4.35318336921277 -4.5369652704176 1.38041746938125e-06 22.1697482795121 4.91110395497776 4.51420871615666 9.00895580671106e-06 -18.9252209934578 14.2938981944337 -1.32400698088277 0.186466807488268 IMMP2L other 0.0141492790611579 1 0.101521922985827 4.51420871615666 -1.32400698088277 0.505660414329798 16.5921807434803 18.8716248927915 0.879213148721396 0.379945452280418 -16.7608847337219 37.7219296577464 -0.444327341835228 0.657106274414852 CLCNKB other 1 1 1 0.879213148721396 -0.444327341835228 7.87994281639289e-05 389.828073972065 110.11615464499 3.54015335196599 0.000460009008057427 -478.397837858756 325.804252112476 -1.46835971217957 0.14300123641014 JAG2 other 0.686500618164148 1 1 3.54015335196599 -1.46835971217957 0.127866204429818 -51.0532491898347 40.2960146591333 -1.26695529624201 0.206092587713887 -165.821077344464 97.8650452437725 -1.69438512935256 0.0911650505469364 FMNL1 other 1 1 1 -1.26695529624201 -1.69438512935256 0.0133234253796451 -0.0725380334712207 3.00259876936242 -0.0241584171056673 0.980741399015095 -16.6504550550779 6.12915273408748 -2.71659979404264 0.00695659199136865 NUTM2A other 1 1 1 -0.0241584171056673 -2.71659979404264 0.481754852979671 5.89056096841488 14.438425627572 0.407978066331976 0.683563463392116 -51.3908973414857 48.534727049011 -1.05884797270191 0.290470122226678 PTRHD1 other 1 1 1 0.407978066331976 -1.05884797270191 3.99425656418985e-06 79.1153860974105 17.5580052661809 4.50594386423823 9.28623524108562e-06 -17.2893803945745 47.2991286014869 -0.365532746707536 0.714956024406146 ZFP90 other 0.0394552663410674 1 0.10452586387366 4.50594386423823 -0.365532746707536 0.618332588153282 0.753514801780087 2.56564216398865 0.293694425651566 0.76918360607166 -5.97247904323134 7.05568574523198 -0.846477473471287 0.397924982115493 FAM227A other 1 1 1 0.293694425651566 -0.846477473471287 0.4999827566455 -134.225957363717 161.453410209432 -0.831360311247711 0.406390018625803 -350.532332963639 300.920405551873 -1.16486727552018 0.244940353823353 MUC6 other 1 1 1 -0.831360311247711 -1.16486727552018 0.0294071112107897 79.7095655220738 29.892013232939 2.66658404373511 0.00805453463349713 31.6507154381446 71.9234339332185 0.440061238838131 0.660191699832334 NOC4L essential 1 1 1 2.66658404373511 0.440061238838131 0.0275389861683573 -39.9717495777788 30.8351580206887 -1.2963043533281 0.195825602921625 -288.18513320172 110.125404811415 -2.61688148792937 0.00930443970135561 USP18 other 1 1 1 -1.2963043533281 -2.61688148792937 0.220659552064106 73.7460197071507 57.6781100619563 1.27857898998311 0.201974773918021 -129.352948550798 150.144449095199 -0.861523348550712 0.389596986047451 NDUFA6 other 1 1 1 1.27857898998311 -0.861523348550712 8.47897681781921e-06 158.867586687452 52.1487556267922 3.04643101792119 0.00250901509992279 -140.235862622143 96.7597970577682 -1.44931951994916 0.148230711155097 SORCS2 other 0.0814660092656069 1 1 3.04643101792119 -1.44931951994916 0.0642669785871123 18.6124145248763 7.91735284500301 2.35083807545895 0.0193453909275721 14.1068408445787 23.456594248505 0.601401921145384 0.54800350095806 TMEM121 other 1 1 1 2.35083807545895 0.601401921145384 0.0240079500820853 13.0782670142495 4.98760622694738 2.62215307687872 0.009156723498218 -7.44298941923372 12.3521044365293 -0.602568530526857 0.547223858301429 TMEM106A other 1 1 1 2.62215307687872 -0.602568530526857 0.0463955391930396 87.7462734252064 57.6420361475535 1.52226186459811 0.128972815824749 -247.169219398216 170.219189930843 -1.45206436183039 0.147504907727338 SIVA1 other 1 1 1 1.52226186459811 -1.45206436183039 0.214708748874421 36.8508498804665 58.595303888132 0.628904492940608 0.529860253160763 -225.814432423574 150.327529701961 -1.50214955884177 0.134044623017406 BRI3BP other 1 1 1 0.628904492940608 -1.50214955884177 1.96710084849274e-14 16.4786977724932 1.97503269709833 8.34350631090985 2.50394256078284e-15 9.75422699921825 4.96576505549228 1.96429490525932 0.050400719837522 IFNE other 2.67801109513802e-10 1 3.61694502905082e-11 8.34350631090985 1.96429490525932 0.199073547063395 58.1573223211026 34.9964766790238 1.6618050683931 0.0975372922139709 16.5395048453384 49.10023253382 0.336851863867367 0.736450773335677 ROBO2 other 1 1 1 1.6618050683931 0.336851863867367 1.81938250074719e-05 53.7216768984509 37.2774607036644 1.44113026704016 0.150525682534237 -316.525481042416 87.2286341195507 -3.62868780690299 0.000331473957939449 AP3M1 other 0.16962103054466 1 1 1.44113026704016 -3.62868780690299 0.00104309817503855 4.89589275216184 1.40867272286704 3.47553599405072 0.000580649271476257 -2.95357550430544 4.51449741880946 -0.654242373026839 0.513428530576169 NT5C1B other 1 1 1 3.47553599405072 -0.654242373026839 0.632013706460041 -6.73489806407392 7.02802045185267 -0.95829232572858 0.33864336965624 -4.38900805208154 34.5869938359388 -0.126897644614635 0.899101610867523 CA13 other 1 1 1 -0.95829232572858 -0.126897644614635 1.44541569066875e-15 77.6642257495857 9.91134449394796 7.83589207266571 6.9458979680292e-14 -53.8890808103869 36.2683241055857 -1.48584424947519 0.1383048275199 UBOX5 other 2.00464702138848e-11 1 9.90207214322243e-10 7.83589207266571 -1.48584424947519 0.0094669125402957 141.193205612863 53.070017368687 2.6605079970479 0.00819928568894818 -131.655297987902 145.938622291705 -0.90212786663661 0.367673878246828 MAFF other 1 1 1 2.6605079970479 -0.90212786663661 2.4733838876851e-16 142.033193656752 17.542438095594 8.09654808999587 1.23757585179605e-14 -64.6192644478339 51.7271168672078 -1.24923383249297 0.2125041123009 BRF1 essential 3.46249010437038e-12 1 1.77715892317913e-10 8.09654808999587 -1.24923383249297 1.74757241096002e-06 2248.65704155477 491.837571159972 4.57195052474629 6.92126474831903e-06 -1209.10845524698 1019.36019732651 -1.18614446435924 0.23644795273496 SEMA4B other 0.0177361123988332 1 0.0785840399524142 4.57195052474629 -1.18614446435924 0.192796238430746 -11.5426945272369 22.536149971003 -0.512185734568186 0.608875441386094 -69.3576184738591 38.7577618416653 -1.78951557515631 0.0744803155645121 MROH2A other 1 1 1 -0.512185734568186 -1.78951557515631 0.0694033116434072 88.5166682706443 147.540395549984 0.599948698393291 0.548966348230461 -604.444912158472 305.785518513276 -1.97669567577063 0.0489369835953931 CIB1 other 1 1 1 0.599948698393291 -1.97669567577063 0.461848839422719 5.9526072387372 4.86281667255836 1.22410685813609 0.221815213911026 -0.402314279555559 12.1612330422105 -0.033081701350444 0.973630124165371 ANKS1B other 1 1 1 1.22410685813609 -0.033081701350444 5.53880456893035e-07 149.931009432002 28.8596053393448 5.19518571612615 3.66128885175203e-07 -46.0685004500224 123.083489760215 -0.37428659635643 0.708440553710675 SLC24A3 other 0.0058367922547388 1 0.00445285950150082 5.19518571612615 -0.37428659635643 2.59785487955778e-09 34.1804113680977 5.58703500207344 6.11780870451191 2.82048973085078e-09 -9.75726323575434 20.6356909604558 -0.472834336124348 0.636659872233392 EFCAB10 other 3.09404516155332e-05 1 3.7083798981226e-05 6.11780870451191 -0.472834336124348 0.0777647327097643 1365.27375534409 675.734838071957 2.02042824851174 0.044171707590512 -1129.00410065798 1834.97297429203 -0.615270151917944 0.538813628826319 KRT76 other 1 1 1 2.02042824851174 -0.615270151917944 1.8585477689769e-09 533.208190366432 83.5523100991059 6.38172888019452 6.20773326000902e-10 69.0892047984495 245.592631888319 0.281316276743462 0.778651365037148 FLRT2 other 2.22263727691947e-05 1 8.30408478191406e-06 6.38172888019452 0.281316276743462 5.29569514988775e-14 111.919589445827 21.2689846389405 5.26210307383072 2.64817927187744e-07 -354.001905719592 77.9708464509442 -4.54018292519519 8.02792818505112e-06 INTS5 other 7.15077716089343e-10 0.118436024514059 0.0032432251542683 5.26210307383072 -4.54018292519519 0.0460156581593679 -29.0817252284848 37.4635527191904 -0.776267148139101 0.438164634566759 -182.198866732778 73.1808206903065 -2.48970789086698 0.0132921650898213 RPS27L other 1 1 1 -0.776267148139101 -2.48970789086698 0.147709929490008 -3.45435794644836 23.9594506816076 -0.144175172976737 0.885453470413464 -110.901262832458 56.9088029447323 -1.94875409592012 0.0522039713119491 MANEAL other 1 1 1 -0.144175172976737 -1.94875409592012 0.0467257043291572 92.5636077687529 37.5271606176496 2.46657637415869 0.0141871025289634 44.0471301638774 110.819174818689 0.397468490772852 0.69129822729886 ADSSL1 other 1 1 1 2.46657637415869 0.397468490772852 0.0063284464925804 2.92644574451378 47.018853741319 0.062239835973332 0.950410696127324 -225.941399886205 88.6962289309497 -2.54736196351821 0.0113216254872405 ANO9 other 1 1 1 0.062239835973332 -2.54736196351821 4.00127661207879e-06 125.09407965444 41.7756724151867 2.99442408517557 0.00296472202248586 -337.268993993278 102.158595824833 -3.30142550678338 0.00107100482729758 FAF1 other 0.0395206090975022 1 1 2.99442408517557 -3.30142550678338 0.164335073121784 4.75485682996561 6.87597087211186 0.691517884296276 0.489744682050261 29.0419149259616 15.3979612796232 1.88608832030212 0.0601941763428529 MYADML2 other 1 1 1 0.691517884296276 1.88608832030212 0.0469829650905044 195.227458816273 78.6602224779172 2.48190829705675 0.0135809075311906 57.2621591580787 491.554038804589 0.116492093722462 0.907335625546784 FAM43A other 1 1 1 2.48190829705675 0.116492093722462 1.73354191424091e-05 29.5024541857026 15.1842705108684 1.94296157754736 0.052908687696975 -106.075973992889 32.6440657127472 -3.24947189257332 0.00128071857006732 NSMCE3 other 0.161947485628385 1 1 1.94296157754736 -3.24947189257332 2.72786682104572e-24 610.044047061411 53.9926512633868 11.2986495900247 3.89498367007994e-25 30.5387263253988 266.076037553416 0.114774432926031 0.90869589711474 HSF1 essential 4.05333730939183e-20 1 5.86974039081047e-21 11.2986495900247 0.114774432926031 6.37000848438191e-14 87.3311049517875 15.6359619000868 5.58527230430912 5.02369750024054e-08 -161.775495505676 36.1247753331408 -4.47824225933007 1.05158888577398e-05 C6orf120 other 8.59441544712807e-10 0.154720272763926 0.000632935648055306 5.58527230430912 -4.47824225933007 2.24696421320492e-06 90.9463391390969 26.4644775594804 3.43654390813837 0.000666981192226489 -98.6488933157448 38.8586293518719 -2.53866116641586 0.0116012353568564 PURA other 0.0226134478416943 1 1 3.43654390813837 -2.53866116641586 0.613270416513852 4.97327915968947 14.6947699405789 0.338438722062331 0.735256643534351 -34.2223548469873 41.2663488386564 -0.829304162110154 0.407556341904458 INPP5J other 1 1 1 0.338438722062331 -0.829304162110154 0.62307258996793 -2.81102271727121 3.7161666324727 -0.756430751169191 0.44994924062043 3.94792242218137 6.84197006973003 0.577015447589813 0.564335991537964 MFSD6L other 1 1 1 -0.756430751169191 0.577015447589813 0.00408974390105069 16.44050678639 5.56607641943852 2.95369764040151 0.00337704554422236 -15.7496183872983 13.8008565029198 -1.14120586530019 0.254653853777394 LRRC37B other 1 1 1 2.95369764040151 -1.14120586530019 0.00045716296751955 81.4809390329361 20.8343487312538 3.91089446010405 0.000112448964464205 9.47242222258438 50.1297083216443 0.188958255288601 0.850246073302471 DDX51 essential 1 1 1 3.91089446010405 0.188958255288601 0.301693538926751 -51.2373952205661 38.2861127533283 -1.3382762452454 0.181756520743651 -102.861096202243 72.2228117326728 -1.42421893768101 0.155357516020359 SIGIRR other 1 1 1 -1.3382762452454 -1.42421893768101 0.00232286190086311 511.641201623963 296.789767988064 1.72391792713198 0.0856914940548304 -807.672036447472 556.733181195905 -1.45073450573313 0.147836386200235 IFITM2 other 1 1 1 1.72391792713198 -1.45073450573313 0.0158270105774083 -772.512121372392 332.805275960781 -2.32121356592745 0.0209091822642715 916.011998852096 976.916831015748 0.937656072420898 0.349135014130744 TNFAIP2 other 1 1 1 -2.32121356592745 0.937656072420898 8.6565770152129e-07 54.2575340935188 27.2580525528341 1.99051395870456 0.0473873767958838 -126.257360289508 39.0665653444707 -3.23185207545709 0.0013583796753743 ZNF445 other 0.00900457141122446 1 1 1.99051395870456 -3.23185207545709 0.0279990049058799 15.6401825622688 6.13000776289461 2.55141317388536 0.0112024560790172 -10.5056654993397 18.289456535659 -0.574411026312169 0.566100966121505 PGBD2 other 1 1 1 2.55141317388536 -0.574411026312169 2.45837925904137e-12 296.807864941681 81.7737945242938 3.6296207931687 0.000330325768989155 -705.543603522451 152.508575993151 -4.62625527074711 5.41455791741462e-06 RAB11B other 3.2091682847526e-08 0.0802329192202498 1 3.6296207931687 -4.62625527074711 2.09429304944447e-13 122.317365677773 23.3097876918592 5.24746802908427 2.81288120657104e-07 -147.860994415229 49.4584701848999 -2.98959902848698 0.00300994350418436 PRMT3 other 2.79860380197264e-09 1 0.00343930985127441 5.24746802908427 -2.98959902848698 0.417501276838829 -2.83233778363086 3.18952351700169 -0.888012823399216 0.37520082672096 -7.15031799530384 7.14478094254226 -1.0007749786601 0.317691761368034 GP1BA other 1 1 1 -0.888012823399216 -1.0007749786601 1.67997939816229e-05 134.652527714016 29.1150648328401 4.62484038717082 5.55289711673713e-06 -15.5988838241532 86.8990586613722 -0.179505785959533 0.857660159864894 PRPF39 other 0.157212472080027 1 0.0634029792789046 4.62484038717082 -0.179505785959533 0.461401712194894 -7.09677740477745 7.7088862713888 -0.920596977946975 0.357956529617441 -18.2801949584023 17.4176227903897 -1.04952295605395 0.294731955553306 PPIL6 other 1 1 1 -0.920596977946975 -1.04952295605395 3.79748317070774e-18 100.498666307019 10.7192056248794 9.37557033832439 1.51812314356912e-18 -2.09033946732204 43.4826800786285 -0.0480729215297249 0.961689182775539 ZNF74 other 5.42128697450237e-14 1 2.23832076287831e-14 9.37557033832439 -0.0480729215297249 0.140663771763583 -2.12549952305002 2.17370558549762 -0.977823094917168 0.328905108237612 -5.96587873319364 3.02096479785064 -1.97482563763678 0.0491526544201202 KIAA0825 other 1 1 1 -0.977823094917168 -1.97482563763678 0.135120012374612 185.633460653109 93.553439747705 1.98425051129841 0.0480872549745341 12.9118628989239 230.793156555559 0.0559456055440517 0.955420273490964 UBALD2 other 1 1 1 1.98425051129841 0.0559456055440517 0.0282917797811016 3.52346322502317 2.09880871172716 1.67879197629384 0.0941687563417521 -4.16112504635681 4.3547327933978 -0.95554084343946 0.340025551913125 CDNF other 1 1 1 1.67879197629384 -0.95554084343946 0.0366927906074749 28.6661207053048 11.6912076821706 2.45193836980771 0.0147462441299448 35.2986575918271 26.181141041804 1.34824748606124 0.17853832168317 NOTUM other 1 1 1 2.45193836980771 1.34824748606124 0.562974572019817 2.56262114370486 3.67191966021335 0.697896844386832 0.48588260779496 -3.35061018527543 6.70372930788667 -0.499812870029458 0.617641257127242 RBM11 other 1 1 1 0.697896844386832 -0.499812870029458 0.000133176117173769 39.3183533845808 9.27752280958626 4.23802282048329 2.9580054149097e-05 15.2984310843147 29.8675904010732 0.512208413162282 0.608860703076901 ZBTB37 other 1 1 0.321180227950895 4.23802282048329 0.512208413162282 0.000834275119819212 6.0708239338275 1.63626288904669 3.71017638697682 0.00024913403622044 8.90917749847817 10.0923831477713 0.88276251188953 0.378111189357098 NUPR2 other 1 1 1 3.71017638697682 0.88276251188953 0.000100926064176083 154.842523191095 39.2344077069279 3.94660024812233 9.74845988031612e-05 -74.2677957416733 90.4923381965399 -0.820708108794486 0.412423502140421 CCDC137 other 0.869175264684423 1 1 3.94660024812233 -0.820708108794486 0.889639401763893 -5.63956861147797 13.6223358313608 -0.413994243079427 0.679156532412662 -12.3397778104483 31.8292239257399 -0.387687046320639 0.69850619739261 SFTPA2 other 1 1 1 -0.413994243079427 -0.387687046320639 0.0376817298438485 15.1421240012323 7.9551152517468 1.90344495611265 0.0578880521682763 61.8721894080775 32.7964064611834 1.88655392722087 0.060134124819699 RGPD2 other 1 1 1 1.90344495611265 1.88655392722087 0.0162899948203032 39.6854663172922 35.1248940885112 1.12983874676714 0.259412037314143 -103.610003373585 52.4838040150332 -1.97413288381131 0.0492484015822407 ARL15 other 1 1 1 1.12983874676714 -1.97413288381131 0.0215363491480502 14.6983568509851 8.53652525170138 1.7218196417864 0.0860807812800036 -67.9792206468273 34.5930854815513 -1.96511007042379 0.0502771916426395 C12orf56 other 1 1 1 1.7218196417864 -1.96511007042379 0.00652985216653665 16.3598043513371 35.7010027350505 0.45824495386723 0.647088474902409 -240.038429451751 91.1612381910477 -2.63311945093045 0.00887245204600039 CDK10 other 1 1 1 0.45824495386723 -2.63311945093045 0.00656021365236896 7.88430630723064 2.47526241849745 3.18524058229616 0.00159017990044295 5.59758124503039 5.67994024045176 0.985500024307507 0.32513009968616 TMEM105 other 1 1 1 3.18524058229616 0.985500024307507 0.69335223656111 5.26022238236024 30.2871004144347 0.173678639103176 0.862227840202198 -75.7118781274622 98.2734339533513 -0.770420601801717 0.441618842104175 SOCS1 other 1 1 1 0.173678639103176 -0.770420601801717 0.842386403788019 -5.42987402372224 33.4268575358101 -0.16244045728514 0.871062508998483 -54.5942011017174 93.2707819652194 -0.585330153252875 0.558742175660831 TCN2 other 1 1 1 -0.16244045728514 -0.585330153252875 2.83055452260925e-07 237.501033028193 48.3074084939931 4.9164515429911 1.41879084537314e-06 -199.420823551746 134.747248621886 -1.47996211864288 0.139879610958575 GAS2L1 other 0.00304539361087529 1 0.0167800393282281 4.9164515429911 -1.47996211864288 0.0104122732067955 45.8122051916603 19.3362189969127 2.36924319066591 0.018419602918216 -76.4750726937267 50.3142566193146 -1.51994837710411 0.129514459812951 ATP6V0A2 other 1 1 1 2.36924319066591 -1.51994837710411 0.126325202317381 2.10664724625875 5.95059473102977 0.354022974421952 0.723555548000536 -24.4848290493042 13.073189141281 -1.87290406225279 0.0619960555982416 PRKN other 1 1 1 0.354022974421952 -1.87290406225279 2.86992911533004e-15 517.34400742115 71.7852059951811 7.20683322209703 4.14184890720455e-12 -472.793389875432 165.569241848837 -2.85556293304216 0.00457673285429917 HGS essential 3.96050217915546e-11 1 5.76338275437514e-08 7.20683322209703 -2.85556293304216 1.54925712649954e-06 65.4180366386703 45.4573314562971 1.43910860015097 0.15110023553102 -328.455324243282 85.0268110144059 -3.86296181551056 0.000135679141015402 TNFAIP8L1 other 0.0158070704616748 1 1 1.43910860015097 -3.86296181551056 0.0071874165365337 40.9499847114841 14.1096602873234 2.9022658148811 0.00396426838282263 -32.4901894319952 34.8671163388614 -0.931828979380867 0.352134050463553 RAD51D essential 1 1 1 2.9022658148811 -0.931828979380867 0.0246356654975155 56.6501963864884 21.9427670756267 2.58172527608943 0.0102765783230818 -13.7531664433251 62.2983783648904 -0.220762832104086 0.825418333512647 MAPK11 other 1 1 1 2.58172527608943 -0.220762832104086 2.15238483426186e-05 12.0959385063649 30.0675314499015 0.402292370643035 0.687737453113935 -209.216166489357 52.3705409559656 -3.99492085952044 8.03533634231588e-05 SP140L other 0.199289311804305 1 1 0.402292370643035 -3.99492085952044 3.48541151070392e-06 75.1045144386068 19.8099739553251 3.7912475103693 0.000179425496877127 -166.894526622768 62.305592468121 -2.67864440432309 0.0077776224391371 MRPL30 other 0.034585738420715 1 1 3.7912475103693 -2.67864440432309 4.53202688266608e-08 62.7035889388443 13.3316080023383 4.70337778667409 3.81599374886787e-06 -64.173362069273 29.514595140637 -2.17429247338434 0.0304178844475573 TARSL2 other 0.000508901298654574 1 0.044013671899442 4.70337778667409 -2.17429247338434 0.000328642471256002 90.0058718308284 22.2872495748029 4.03844680469615 6.74515549919975e-05 -19.4274211739247 70.6201297894719 -0.275097500271388 0.783419423967698 SMYD3 other 1 1 0.711411550500598 4.03844680469615 -0.275097500271388 0.201617923055288 -147.931302099659 88.4642507829488 -1.67221562145613 0.0954622925611546 -236.418556611134 241.23646803917 -0.980028262446398 0.327814825684254 METTL7A other 1 1 1 -1.67221562145613 -0.980028262446398 0.0115239485585768 66.277081525894 22.344512522666 2.96614578002825 0.00324323056232404 13.7980117711644 43.5317892631699 0.316964039491898 0.751478225082928 IFNLR1 other 1 1 1 2.96614578002825 0.316964039491898 0.0176442513086932 76.2680632201196 36.4255746308001 2.09380535497799 0.0370714031277231 154.2565317428 59.0996270230208 2.6101100719758 0.00948101033006839 SH3BGR other 1 1 1 2.09380535497799 2.6101100719758 0.876203548046738 -8.93224968624789 19.5462964663058 -0.456979136771278 0.647999031670077 3.50034026160542 40.6017921625023 0.0862114718383823 0.93135273853447 FAM174B other 1 1 1 -0.456979136771278 0.0862114718383823 0.0304461469652829 4.73881983567513 1.78843552041506 2.64970125094325 0.00846020416957465 2.69371419143174 7.81983337459467 0.344472070234024 0.73071970827385 KPNA7 other 1 1 1 2.64970125094325 0.344472070234024 0.265574734070315 -27.975952948331 17.2016416513424 -1.62635366527053 0.104858755846902 -23.985014086453 32.3205516877668 -0.742097917082623 0.458572348012028 GPRIN3 other 1 1 1 -1.62635366527053 -0.742097917082623 0.619858904783358 8307.62404685984 15056.9488969345 0.551746844843925 0.581508107308943 -27901.7962270185 40873.8306399623 -0.682632280609857 0.495334640802701 KRT6B other 1 1 1 0.551746844843925 -0.682632280609857 0.985975319299298 -2.49727570413587 16.2187921621064 -0.153974209619043 0.877727739333789 1.98083552266035 42.1387638798793 0.047007442560653 0.962536802892237 PARPBP other 1 1 1 -0.153974209619043 0.047007442560653 0.269207985691807 221.423394844969 154.244538203781 1.435534751658 0.152111502030039 517.2420921506 508.872847476746 1.01644663242567 0.310184632050816 STAC3 other 1 1 1 1.435534751658 1.01644663242567 0.979526834197845 2.73198975662848 13.900549395556 0.196538257509583 0.844313650985505 -0.00893629489888401 32.5170052222706 -0.00027481912426436 0.999780897307087 ROR1 other 1 1 1 0.196538257509583 -0.00027481912426436 1.66414870635844e-13 81.3644997972545 10.1228281796907 8.03772407798991 1.78469583760849e-14 -0.0827392689567418 62.1338000705492 -0.00133163059176803 0.998938342567719 SDHAP1 other 2.22779587320205e-09 1 2.5587184223793e-10 8.03772407798991 -0.00133163059176803 0.626187856132977 100.236802162427 180.061215984664 0.556681801876559 0.578136396187368 -514.741793407198 631.207633420617 -0.81548727574432 0.415403810732198 MUC1 other 1 1 1 0.556681801876559 -0.81548727574432 1.48210576240434e-12 162.039628942486 24.5836859120957 6.59134799890847 1.79674114673894e-10 -128.785744323703 56.7011291795813 -2.27130828234159 0.0237921652329145 FAAP100 other 1.94585665546066e-08 1 2.42919403039104e-06 6.59134799890847 -2.27130828234159 0.000249474243896739 198.454796432033 128.2360465199 1.54757419475839 0.122713224190765 -523.213024388734 241.486668934027 -2.16663315908206 0.0310005292051248 IRF7 other 1 1 1 1.54757419475839 -2.16663315908206 0.40907257407068 3.20739673026592 5.09888555759413 0.629038776029973 0.529775272548927 -22.9972188294201 23.0874036828768 -0.996093763738206 0.319961931168912 L3MBTL1 other 1 1 1 0.629038776029973 -0.996093763738206 0.0401802687690176 -64.2780345545226 28.8028308951567 -2.23165683916615 0.0263319875717082 -110.728709993923 59.9630750917906 -1.84661493468141 0.0657290613021119 SV2B other 1 1 1 -2.23165683916615 -1.84661493468141 0.818015188035608 0.157603923024549 5.68177236167235 0.0277385141452869 0.977887996256016 -6.70441030598396 11.3571257682321 -0.590326324001571 0.555388539251333 FAM131C other 1 1 1 0.0277385141452869 -0.590326324001571 0.00414007208901032 1.66709240378315 5.92161331405716 0.281526725128384 0.778488396056317 -28.0612111338606 11.1512379922375 -2.51642115013546 0.0123441154052971 LMNTD2 other 1 1 1 0.281526725128384 -2.51642115013546 0.115708840727369 0.43272727272727 2.60489804772466 0.166120617697591 0.868166937347371 12.3487445887446 6.00807630034856 2.05535748406327 0.0406557297770293 PDE6G other 1 1 1 0.166120617697591 2.05535748406327 0.713181771988652 13.259913482336 19.2703400014644 0.688099612219003 0.491891677875854 -6.4981339327368 40.6977352477642 -0.159668195126258 0.873243822438463 PRKG1 other 1 1 1 0.688099612219003 -0.159668195126258 0.269816428016369 172.04357053683 106.458842912819 1.61605711493332 0.107079843900078 193.251186017479 319.753091580665 0.604376286284405 0.546027174278257 DLK1 other 1 1 1 1.61605711493332 0.604376286284405 0.00351327934844236 53.6880307219698 15.8810306928505 3.38063893712766 0.00081275139092126 -3.27073880371396 30.1157011004454 -0.108605766566915 0.91358325469169 TLCD2 other 1 1 1 3.38063893712766 -0.108605766566915 0.816827435193329 11.3409036259389 50.9158521729344 0.22273816781893 0.823881842358815 126.684738398759 201.665357184473 0.628192864493203 0.530327082260705 LSAMP other 1 1 1 0.22273816781893 0.628192864493203 1.285319866282e-22 6008.63435836663 621.34391534718 9.67038416238336 1.63839982939957e-19 -4023.56200900263 1916.02484165978 -2.09995294503445 0.0365382778147715 AHNAK2 other 1.89636093071247e-18 1 2.42548710744313e-15 9.67038416238336 -2.09995294503445 0.00269719003035683 590.350299430298 172.636896540813 3.41960676575725 0.000709136596203585 -60.0277695102547 339.21854404235 -0.176958985776321 0.859653613616318 OLFML2A other 1 1 1 3.41960676575725 -0.176958985776321 0.243706891247428 106.133291826651 110.349703206498 0.961790460170456 0.336885624217275 -343.228195995923 299.433672149062 -1.14625784579451 0.252550275381928 SP1 other 1 1 1 0.961790460170456 -1.14625784579451 3.05226514572321e-08 125.853672527032 23.290269552012 5.40370184406731 1.28757596372225e-07 -128.50881922735 88.3299891345945 -1.45487190122408 0.146697334604109 MRPL40 essential 0.00034615739017647 1 0.00159582164943736 5.40370184406731 -1.45487190122408 6.25636830810404e-10 -13.5069905442665 20.3638713232137 -0.663282061150585 0.507628941438087 -173.115717569772 28.7566595122145 -6.02002181429454 4.7909929790415e-09 FAM212A other 7.62401042025558e-06 7.29380771129278e-05 1 -0.663282061150585 -6.02002181429454 0.00420746247592281 47.9962411593056 14.3938400660647 3.33449871188042 0.000956536237124951 43.9803492338604 38.8310059990562 1.13260906078326 0.258239838713643 PDIA2 other 1 1 1 3.33449871188042 1.13260906078326 2.71299638916746e-13 173.389731665946 47.8094419204449 3.62668386622182 0.000334418683039711 -350.923410525415 88.1956551055525 -3.97891948424704 8.58496508240777e-05 PCGF3 other 3.61669548639914e-09 1 1 3.62668386622182 -3.97891948424704 2.56429526585802e-14 79.0544267799757 9.60590819733639 8.2297712153752 5.21144601977917e-15 81.3541102248057 61.6217969615018 1.32021645320781 0.187733586764514 LMLN other 3.4841079777213e-10 1 7.50813028069585e-11 8.2297712153752 1.32021645320781 6.6582360176796e-11 4355.19635456214 694.531662315185 6.27069519054657 1.16743857738052e-09 -2880.21840363756 1555.38046931229 -1.85177740139108 0.0649816602811233 P4HB other 8.38138749905508e-07 1 1.55094215005002e-05 6.27069519054657 -1.85177740139108 7.25891448549383e-11 459.464832370391 154.049288452966 2.98258328217253 0.00307926464690439 -993.913325603833 289.03223012924 -3.43876295442694 0.00066223849634245 PSMD13 essential 9.1222778339201e-07 1 1 2.98258328217253 -3.43876295442694 0.237788456850584 162.829969736199 97.7544927604279 1.66570318292434 0.0967542101721342 -120.435428651446 319.221618520908 -0.377278422462349 0.70621757439007 PBX1 og 1 1 1 1.66570318292434 -0.377278422462349 0.0418704502722142 871.685567421945 471.518800285018 1.84867616496954 0.0654269025388437 -2096.73906454368 1555.60201569571 -1.34786342739853 0.178655717542925 NDUFA4L2 other 1 1 1 1.84867616496954 -1.34786342739853 0.166812353689403 -27.3874276682723 14.5218199291325 -1.8859500945422 0.0602157446753438 -25.6987892862026 29.5380620579597 -0.870022861884991 0.384946223054708 SHC4 other 1 1 1 -1.8859500945422 -0.870022861884991 0.137977036356381 282.486415666804 215.318980806208 1.31194386397848 0.190479443410126 -711.812604268157 584.703478895403 -1.21739074584075 0.224352562230629 KRT79 other 1 1 1 1.31194386397848 -1.21739074584075 1.67303908767064e-05 1546.93161522862 345.168090805037 4.48167619324458 1.0358014116873e-05 -563.819751742989 1098.87197221477 -0.513089573671275 0.608246040663553 ZFP36L1 other 0.156596458605972 1 0.116040832151328 4.48167619324458 -0.513089573671275 5.24174056419248e-10 336.078324563744 53.0242396896803 6.3382016702288 8.0098855728599e-10 -198.488450119612 174.151306684474 -1.13974711932097 0.255254844316425 UBE2L3 essential 6.40907618783814e-06 1 1.06899932855388e-05 6.3382016702288 -1.13974711932097 5.8021633186638e-06 13.3556620225364 2.82992350935224 4.71944276175631 3.54058324968301e-06 -14.3524043201018 15.6479758872703 -0.917205165926771 0.359725881797853 NTF3 other 0.0565710923569721 1 0.0409185206165865 4.71944276175631 -0.917205165926771 5.10931195924842e-09 179.975425545527 50.2012705763749 3.58507710022433 0.000390226231874185 -283.630071213009 81.458911877314 -3.48187895807136 0.000568023693992118 BRWD1 other 6.01212738244762e-05 1 1 3.58507710022433 -3.48187895807136 0.0718267848408321 3.67445115165414 7.58175781632144 0.484643698819298 0.628260673260202 -45.8746597549754 21.6617521357918 -2.11777235134994 0.0349651686621312 PMEL other 1 1 1 0.484643698819298 -2.11777235134994 0.000632660816917521 62.6412947761389 18.0549051212724 3.46948900342515 0.000593385808682422 -45.7426739618457 43.1041776653453 -1.06121207825806 0.289398825053419 POU3F1 other 1 1 1 3.46948900342515 -1.06121207825806 0.0713353764563349 -2.8974224382677 2.50174843151175 -1.15815899063714 0.247662796211464 7.94492315732784 6.36528458304513 1.24816464270746 0.212883257989962 SNAI3 other 1 1 1 -1.15815899063714 1.24816464270746 0.00908395429038326 6.83261027895344 3.94414507164511 1.73234253680825 0.084197682278358 -28.8778626450598 14.7548138027552 -1.95718245117179 0.0512145783915938 ZBTB3 other 1 1 1 1.73234253680825 -1.95718245117179 0.163450112551251 10.9067624386827 10.0835463964137 1.08163953532874 0.280232281529687 -31.508059679601 24.2621089922387 -1.29865296086504 0.195003978255666 EP400NL other 1 1 1 1.08163953532874 -1.29865296086504 0.0714512551807687 124.642302398883 59.7126858764536 2.08736720797938 0.0376457613138003 262.385568201082 193.161812775493 1.35837184602345 0.175302566058674 PRAME other 1 1 1 2.08736720797938 1.35837184602345 0.000263909868655237 22.5603240804351 7.57178412718223 2.97952552548942 0.00310930949859582 -23.4869620266255 16.9606054303539 -1.3847950253351 0.167085938057747 C6orf201 other 1 1 1 2.97952552548942 -1.3847950253351 0.000218959167606621 18.6539538721156 5.35279458787246 3.48490000239853 0.000561885550508074 -44.9760165309046 25.3118315937535 -1.7768772032287 0.0765503703768328 MYBL1 other 1 1 1 3.48490000239853 -1.7768772032287 2.6563895658941e-08 199.380170214649 35.6216583581468 5.59716137328711 4.7201526128872e-08 -104.610134480878 101.061283893985 -1.03511582725008 0.301403811595392 DRG1 other 0.000302244004807431 1 0.000595447252115721 5.59716137328711 -1.03511582725008 1.01405237906462e-09 299.992774937364 57.4959988415273 5.21762872168228 3.26394788631157e-07 -425.004746466363 109.031482217493 -3.89800026398407 0.000118173456945884 ANKFY1 other 1.22497527391006e-05 1 0.00397679410468201 5.21762872168228 -3.89800026398407 8.1090526937732e-11 271.577840445001 39.6738604068803 6.84525875878474 4.01670615597163e-11 -161.65753947846 187.256395789926 -0.863295156336428 0.388634121646581 YTHDF3 other 1.01752393201466e-06 1 5.49565736260038e-07 6.84525875878474 -0.863295156336428 4.1750405358389e-17 36.8662943893427 4.0079021575605 9.19840179226885 4.80737675537331e-18 32.003805187782 19.7532250301137 1.62018126857728 0.106178335208581 ZNF696 other 5.89139970012227e-13 1 7.06540161737216e-14 9.19840179226885 1.62018126857728 0.0105926768487368 -31.2631552824886 20.5630896461183 -1.52035301214524 0.12942538027418 -123.861883756111 40.7757554659564 -3.03763553466283 0.00258380944920972 ADARB2 other 1 1 1 -1.52035301214524 -3.03763553466283 0.125539607489496 205.179225746994 100.434474545501 2.0429163061339 0.0418822909889817 143.259099784747 295.60881513771 0.484623909872274 0.628275736403784 SRL other 1 1 1 2.0429163061339 0.484623909872274 0.0460546228227204 11.5862394302551 13.4596311745862 0.860814035687072 0.389995205087232 -31.1143297138623 24.5589921236493 -1.26692209343153 0.206119057061362 C11orf87 other 1 1 1 0.860814035687072 -1.26692209343153 0.0189357310016904 145.650734253733 256.947870359294 0.566849353723258 0.571215162386135 -1170.99158422995 514.898962213754 -2.27421624466944 0.0236168265254815 IFIT1 other 1 1 1 0.566849353723258 -2.27421624466944 0.208499415333071 22.7883874518438 17.0488038684078 1.33665608612413 0.182299531193022 -35.6978880022013 40.5403627447841 -0.880551765827358 0.379231795853452 KCNQ5 other 1 1 1 1.33665608612413 -0.880551765827358 0.0422884608727256 44.4364791124737 24.9821081867498 1.77873215423998 0.0762389268799236 -26.8147609598019 41.2595448450156 -0.649904429642326 0.516223151409476 ADAMTSL5 other 1 1 1 1.77873215423998 -0.649904429642326 0.582715779079766 0.953686036426727 1.70462790374324 0.559468746424074 0.576235679806183 -1.30145514117759 3.16585072130591 -0.411091758818225 0.681282145054509 KCNIP4 other 1 1 1 0.559468746424074 -0.411091758818225 2.10692630156101e-05 372.478459235749 101.249537050134 3.67881641820558 0.00027481395110074 -273.882659961716 197.03845354224 -1.38999598828562 0.165496239170658 MORF4L1 other 0.19529099889169 1 1 3.67881641820558 -1.38999598828562 5.32341424315121e-16 66.0963347428992 7.45512961248157 8.86588673552221 5.41486194005354e-17 -9.2224793682056 45.7594977035475 -0.201542408265785 0.840402526540727 WDR53 other 7.42350116207436e-12 1 7.90786437725419e-13 8.86588673552221 -0.201542408265785 9.55833967317747e-14 157.842138121685 22.4875844125512 7.0190792939764 1.34117088251995e-11 -123.364464623507 53.9470526455292 -2.28676931498185 0.0228620224688263 DMWD other 1.28559668604237e-09 1 1.85135228623054e-07 7.0190792939764 -2.28676931498185 3.08560784094116e-16 473.739934556302 53.4494819747596 8.863321346688 5.51587617997289e-17 -39.9760164999269 263.399296762644 -0.151769640205039 0.879464266249173 SLC52A2 other 4.31337120085164e-12 1 8.05428239799641e-13 8.863321346688 -0.151769640205039 1.73965330546943e-11 53.0532229450028 11.4167226600286 4.64697483900077 4.94075621422211e-06 -70.334628706598 19.0777017569629 -3.68674537439644 0.000266997035600469 PIGP other 2.22414675104267e-07 1 0.0565963624339143 4.64697483900077 -3.68674537439644 0.00837045976794495 -49.4658572433177 16.2690520857596 -3.0404879757325 0.00256145383151902 -98.2216303626734 96.7640424846011 -1.0150633214637 0.310859635996078 IKZF1 other 1 1 1 -3.0404879757325 -1.0150633214637 0.000120170150210126 164.549646447278 38.5605258896537 4.26730815129855 2.61369975813817e-05 32.1199754704811 86.3519487813702 0.371965843548058 0.710166022370602 PCYT2 other 1 1 0.285023958624967 4.26730815129855 0.371965843548058 0.00142880671825483 20.670611752162 7.60103138861587 2.71944828212662 0.00689606004852679 49.7764529870832 14.0540870664911 3.54177775842617 0.000456512378887532 NAT8L other 1 1 1 2.71944828212662 3.54177775842617 1.15240400734786e-08 86.6479065027554 13.9263158878864 6.22188288706886 1.57364673242455e-09 55.5633632613539 56.742358703048 0.979221952195111 0.328226572296199 GNB1L other 0.000133321619610074 1 2.08287881503713e-05 6.22188288706886 0.979221952195111 0.000242483068278395 28.8033733073453 7.15099265386205 4.02788461708032 7.03515694298996e-05 18.3286275785758 23.4169019321847 0.782709328144922 0.434376656659516 DNAH14 other 1 1 0.740872377666273 4.02788461708032 0.782709328144922 0.102773879256193 1.55838928513348 4.10171890757618 0.379935661182197 0.70424521100642 24.613457279155 11.5030405040759 2.13973490490915 0.0331322630548355 LINC01405 other 1 1 1 0.379935661182197 2.13973490490915 0.00152007627081836 125.888049023138 37.0601162724084 3.39686060609754 0.000767654038563707 153.454025629245 127.23608409077 1.20605743823247 0.228686291540088 CCDC190 other 1 1 1 3.39686060609754 1.20605743823247 0.24241052469612 -31.4623564945057 22.0188531407408 -1.42888261679224 0.154031990704003 -59.0781943624637 54.5708838954867 -1.08259551880467 0.279818645823256 EVI2B other 1 1 1 -1.42888261679224 -1.08259551880467 0.031035326324514 9.52160391151494 4.4741756532493 2.12812474284509 0.0340954531756332 -10.2813364673313 11.9314516753022 -0.861700382076176 0.389501715509723 ZNF829 other 1 1 1 2.12812474284509 -0.861700382076176 0.45862534300596 14.8253008181976 103.25404859238 0.14358081857617 0.885922716296988 -242.563069337214 221.105491275147 -1.09704678946831 0.273453586125769 TMPRSS11B other 1 1 1 0.14358081857617 -1.09704678946831 5.62569077238338e-05 21.8999244466568 10.7913045685891 2.0294047218723 0.0432469709922258 -54.4935801229453 21.6990909415437 -2.51133009533664 0.012521568807305 THNSL1 other 0.49905502841813 1 1 2.0294047218723 -2.51133009533664 0.00305190218431633 17.783443738385 75.0233722324103 0.237038714859348 0.812779864950016 -468.015471194772 151.787195727207 -3.08336595160433 0.00222664249949048 TRIM69 other 1 1 1 0.237038714859348 -3.08336595160433 5.56389157232045e-08 363.266118680612 112.513947848465 3.22863187744388 0.00137285541481751 -1252.95877950547 322.216162285484 -3.88856589507558 0.000122644604996553 ATP6V0C other 0.000621876161038257 1 1 3.22863187744388 -3.88856589507558 0.000482286680102722 1410.08345774253 579.567122844043 2.43299421613668 0.0155237041940867 -1168.53270265028 1087.18117273672 -1.07482794216237 0.283264057980633 IFITM1 other 1 1 1 2.43299421613668 -1.07482794216237 2.14913995421105e-22 2267.55597104129 218.009933929923 10.4011589296209 5.62679114637099e-22 -288.720147839572 533.529170201707 -0.541151569520403 0.588785607487856 LAMP1 other 3.16611298054372e-18 1 8.41486615939781e-18 10.4011589296209 -0.541151569520403 4.741756417057e-07 14.1262622918473 5.85477253683667 2.4127773031264 0.0165031871709749 -37.4231730124628 12.9538512391636 -2.88896115306008 0.00418097642706785 POMK other 0.00502152004566336 1 1 2.4127773031264 -2.88896115306008 0.290781187976936 -80.9370197789125 51.7469457729245 -1.56409269320125 0.119747142063017 -77.5660371123116 103.409753266023 -0.750084345649411 0.4542918848335 LINC00839 other 1 1 1 -1.56409269320125 -0.750084345649411 0.00132583332648714 52.4755890082941 50.862475990963 1.03171518857276 0.302987122706273 -174.913755655303 71.8249924489053 -2.43527704899841 0.0154279231284682 KLHDC8B other 1 1 1 1.03171518857276 -2.43527704899841 1.42786755488557e-06 32.6567724863976 14.975208012533 2.18072246202301 0.02994348866327 -96.4557002380415 25.2126456399173 -3.82568737988093 0.000157241851175412 SETD4 other 0.0146170801593636 1 1 2.18072246202301 -3.82568737988093 0.627858385617524 36.1369263258891 38.3183125743072 0.943071964763899 0.346357769324359 23.5576285045669 73.4793234834222 0.320602142041792 0.748721828541176 PTCH1 ts 1 1 1 0.943071964763899 0.320602142041792 0.00158370635107476 89.5251302001629 25.629779759462 3.49301207581045 0.000544822290388886 -38.3580975089416 48.7183023470923 -0.787344707450195 0.431662867925495 RTN4RL1 other 1 1 1 3.49301207581045 -0.787344707450195 0.797987326248438 -3.25366625676409 10.4045373553376 -0.312716091609295 0.754700702694952 -12.8615576359677 19.1498286278052 -0.671627819023556 0.502306743943744 CALHM1 other 1 1 1 -0.312716091609295 -0.671627819023556 0.00697349916094152 -16.0889965603713 11.944928812741 -1.34693113810859 0.178955503120604 -76.0162432019815 23.9748302304183 -3.17066867508138 0.00166808954553562 RNPC3 essential 1 1 1 -1.34693113810859 -3.17066867508138 0.0834032034745249 19.608205139131 17.3447129920886 1.13050040943744 0.259156543890207 -93.5767552003123 60.2619883549555 -1.55283218749979 0.121503641136207 ZNF267 other 1 1 1 1.13050040943744 -1.55283218749979 2.00891306021265e-06 187.798927744431 36.3141555585278 5.17150749772369 4.14466298435363e-07 37.378548823262 89.3047652842629 0.418550440217648 0.675830845633428 IRS2 other 0.0202860040820273 1 0.00502954853151313 5.17150749772369 0.418550440217648 0.157326649791993 -30.8175190214776 19.7434597171606 -1.56089760674982 0.119539402167064 -86.0879573215417 79.6556153754938 -1.08075189571666 0.280623867098105 LCE3A other 1 1 1 -1.56089760674982 -1.08075189571666 4.06613973699888e-09 1319.15121969968 218.287928823001 6.0431707186581 4.21288205101365e-09 -543.288997830878 417.173922311423 -1.30230814721278 0.193750538600501 BICD2 other 4.80617716913268e-05 1 5.51044972272585e-05 6.0431707186581 -1.30230814721278 0.116708811517357 -268.778950012559 131.201812261552 -2.04859174869282 0.0413200846962438 -177.64840685564 528.251512970869 -0.336295121724407 0.736869432499241 LCE3E other 1 1 1 -2.04859174869282 -0.336295121724407 0.00241972836939019 72.2928470865487 21.2875718823797 3.39601188364689 0.000772543023746614 86.8529282045668 52.145142234469 1.66559960300876 0.0968001169911689 RASA3 other 1 1 1 3.39601188364689 1.66559960300876 1.22039593824144e-19 186.215605874021 18.5845994478614 10.0198880474365 1.15805232199627e-20 49.4440605226857 119.220004008003 0.414729566016174 0.678625816946666 LRCH3 other 1.76749943735508e-15 1 1.72387668652365e-16 10.0198880474365 0.414729566016174 0.00272691788681263 58.665687714146 17.0223041222755 3.44640110367759 0.000643961605718281 -19.2382933594387 57.8082887310664 -0.332794721686684 0.739507158511517 LEMD1 other 1 1 1 3.44640110367759 -0.332794721686684 0.0591538089125547 116.833361487638 283.032649728722 0.412791109434263 0.680037840746652 -1363.79766182754 643.792777107495 -2.11837987365277 0.0349181781848745 NDUFA13 other 1 1 1 0.412791109434263 -2.11837987365277 0.0354500943533747 8.93009868674077 5.71476496690761 1.56263621311675 0.119132772751785 -24.7623303485132 16.1130533480685 -1.53678696480463 0.125339847418056 ZNF566 other 1 1 1 1.56263621311675 -1.53678696480463 0.000930525038510338 29.6968610969118 8.9177876660252 3.3300704400095 0.000970342665805321 -19.4995471783666 25.6521300369121 -0.760153139341947 0.447726253650534 ZNF529 other 1 1 1 3.3300704400095 -0.760153139341947 3.08798291693262e-26 26.6111386224351 2.28894370240041 11.6259471976214 2.74876978591146e-26 -6.17714890881964 9.63961408448691 -0.640808735150566 0.522107024310276 ZNF284 other 4.62209283006474e-22 1 4.15174188464067e-22 11.6259471976214 -0.640808735150566 0.00726341500279018 2.31721091971983 0.984489046815425 2.35371935037309 0.0191967978577236 -1.86398025592651 1.82618289632961 -1.02069746665181 0.308176117610866 DLEU7 other 1 1 1 2.35371935037309 -1.02069746665181 0.926957895977448 -31.3052994593096 83.1852107999161 -0.376332513415247 0.706919883375559 -39.1358931901633 225.815883500645 -0.173308859339168 0.862518577557055 KRT73 other 1 1 1 -0.376332513415247 -0.173308859339168 0.873738513479065 -0.146953950515274 2.12066490853772 -0.0692961674065728 0.944797567701375 -2.25004199183696 4.34999773637981 -0.517251301769529 0.605341466875027 MATN1-AS1 other 1 1 1 -0.0692961674065728 -0.517251301769529 0.00851398142862065 70.6632607635633 23.9589971590674 2.94934133905603 0.00341913031629339 -85.9531434497784 78.4570078623095 -1.09554449999705 0.274102003914958 AIDA other 1 1 1 2.94934133905603 -1.09554449999705 7.27795011224304e-05 55.9736181286214 15.8314865247887 3.53558827473206 0.000467122690726271 -36.6312766416416 32.0725124490919 -1.14213929138809 0.254252676465114 C15orf41 other 0.637038973324633 1 1 3.53558827473206 -1.14213929138809 0.0698114150136755 -10.147202626332 4.54138641089159 -2.23438432853809 0.0261480168265924 2.94949030312354 10.7792132004402 0.273627606048565 0.784547342673714 CD300LF other 1 1 1 -2.23438432853809 0.273627606048565 0.229941841559641 14899.7645570498 19473.4778841706 0.765131151490993 0.444759131649008 -71686.0703803171 52863.0097941483 -1.35607243438213 0.176035222570911 KRT5 other 1 1 1 0.765131151490993 -1.35607243438213 0.196197610353518 -1.22177564467875 21.5190591732375 -0.0567764433771452 0.954758824576799 -130.968983766913 74.5485940107719 -1.75682701337049 0.0799066807964581 GSAP other 1 1 1 -0.0567764433771452 -1.75682701337049 0.0296808282411126 2.1172876351794 11.4351007197666 0.185156885546227 0.85322476678108 -54.358713239233 23.6429205998637 -2.29915390569583 0.0221481977525582 CYP2R1 other 1 1 1 0.185156885546227 -2.29915390569583 0.843934171776324 -0.00892726371162681 1.45531570725036 -0.00613424541984348 0.995109445297787 -1.11904282933734 2.09611328590454 -0.533865624946142 0.593806316343032 LRRC70 other 1 1 1 -0.00613424541984348 -0.533865624946142 2.5510726583626e-15 81.0716959335124 9.37554381793453 8.64714596911486 2.58890497394026e-16 21.6471602597963 56.7891925917498 0.381184504865475 0.703319300258537 ANKRD46 other 3.52507219932544e-11 1 3.76556228459611e-12 8.64714596911486 0.381184504865475 8.69029073862937e-11 147.309696201939 52.60540038938 2.80027706493187 0.00541920266935928 -416.846579886811 93.6281685398732 -4.45214924512049 1.17932377949146e-05 PIP5K1C other 1.08915413827242e-06 0.173242663207295 1 2.80027706493187 -4.45214924512049 7.03500488294525e-07 27.6730477793393 5.09498542947663 5.43142824692669 1.10823095224724e-07 14.5086193245383 13.4730250142164 1.07686427578285 0.28235206249037 CYP4F2 other 0.00735720810658415 1 0.00137742025054809 5.43142824692669 1.07686427578285 4.37640939247775e-05 38.4237204215813 10.0493598109204 3.8234993218003 0.000158132749516566 -39.2095714536363 20.0841133461136 -1.95226798305357 0.051778169958983 ZBTB6 other 0.393132855726276 1 1 3.8234993218003 -1.95226798305357 0.0944193361520122 9.37256509288354 5.05975403146646 1.85237563616647 0.064907242099451 -13.8890294457232 16.0781392449381 -0.86384557529541 0.388330016491117 C2orf76 other 1 1 1 1.85237563616647 -0.86384557529541 2.84014748317989e-15 129.298211332607 14.9424099787653 8.65310291421212 2.89610080807695e-16 -11.5991816799761 57.6513105274744 -0.201195455469281 0.840679415776836 POLR3C essential 3.91997155628489e-11 1 4.21035135478228e-12 8.65310291421212 -0.201195455469281 0.916004490020557 2.84386299324007 12.2594241751423 0.231973619038845 0.816707711612783 -6.4609190771891 31.3254241505275 -0.206251607197482 0.836726363901581 WWOX other 1 1 1 0.231973619038845 -0.206251607197482 1.83607133014769e-22 61.6272498871804 6.41681268608523 9.60402818377701 2.34426707726347e-19 -4.10187844968235 11.2108301088259 -0.36588534567597 0.714692389110474 CIDECP other 2.70636914063769e-18 1 3.46881199422676e-15 9.60402818377701 -0.36588534567597 6.01162785232527e-06 28.8272934110232 12.5960772267035 2.28859293986462 0.0227564837976727 -47.3805365698066 23.7623651155262 -1.99393184724901 0.0470105484127316 CCDC84 essential 0.0585231971423865 1 1 2.28859293986462 -1.99393184724901 8.02588014409902e-24 1104.67535712831 147.382690483105 7.49528559634311 6.57927166282175e-13 -477.935280444771 278.671563878055 -1.71504861778402 0.0873074275265573 BCL9L other 1.19031828417133e-19 1 9.25177181225995e-09 7.49528559634311 -1.71504861778402 7.76424794219931e-23 270.437580244036 61.2760426886797 4.41343090019744 1.39528919397473e-05 -849.386231696061 114.486424400623 -7.41910000371571 1.08301826873133e-12 POLR1D other 1.14693470602168e-18 1.65983379865764e-08 0.154974770774774 4.41343090019744 -7.41910000371571 0.00193245279152214 62.1796286784947 33.5610105115241 1.85273410218514 0.0648439295772593 -235.045329230571 81.5014647027146 -2.88393994007254 0.00419434605152383 KIF18B essential 1 1 1 1.85273410218514 -2.88393994007254 0.00483919244611626 92.5936553751053 30.9884625952058 2.98800416737778 0.00302526016872265 3.96381066289733 81.1953597768459 0.0488181919975638 0.961094639260688 ZNRF1 other 1 1 1 2.98800416737778 0.0488181919975638 0.212343715369321 -2.52877616814638 3.21681155943311 -0.786112621589813 0.432385051649606 6.46371295044147 6.18027304353448 1.04586203633891 0.296416565744824 FFAR4 other 1 1 1 -0.786112621589813 1.04586203633891 4.74210539769811e-05 149.037505421283 60.4798921572415 2.4642488619821 0.0142569830131072 -439.803442649099 127.2522302398 -3.4561550852218 0.000622156729216501 SAPCD2 other 0.424418433093981 1 1 2.4642488619821 -3.4561550852218 0.348214513120218 -127.192558907855 90.0799938066351 -1.41199564445892 0.15892291856185 117.563142005431 289.280580916857 0.406398319696475 0.684721603390696 EDARADD other 1 1 1 -1.41199564445892 0.406398319696475 0.119250318672822 19.2638899099955 21.5412168931835 0.894280485894528 0.371843946796821 -91.3697886390856 58.26866726928 -1.56807754357644 0.117851319493274 CYP4F12 other 1 1 1 0.894280485894528 -1.56807754357644 0.000206022923939451 65.068641686624 18.5427065023253 3.50912320585262 0.000514225956994996 128.205530397114 60.3685337161528 2.12371450000633 0.0344632841393457 MARC1 other 1 1 1 3.50912320585262 2.12371450000633 0.897205221623768 -9.80519476185367 24.9787462385394 -0.39254150981867 0.694921956710419 -18.1359628630925 47.7072567587661 -0.380151031420605 0.704087886557798 SOWAHB other 1 1 1 -0.39254150981867 -0.380151031420605 1.66460610459712e-17 59.9159110810603 10.8419431211667 5.52630745351233 6.80338665432196e-08 -61.6320538257758 20.1167641203884 -3.06371608559607 0.00237243197031647 BLOC1S4 other 2.36157668059193e-13 1 0.000852736483252714 5.52630745351233 -3.06371608559607 3.81493782259992e-05 20.1174194703544 6.07272161960423 3.31275179903035 0.00102995703337515 -28.9250233128656 15.0944633958096 -1.91626708114019 0.0562245503671903 ZNF749 other 0.344755931028355 1 1 3.31275179903035 -1.91626708114019 0.000902299862679237 115.375620026088 49.1727869853087 2.34633070646491 0.0195690236777995 -357.628575008335 155.003659757392 -2.30722665237767 0.0216801762927472 MKL2 other 1 1 1 2.34633070646491 -2.30722665237767 0.189989899469994 -1.43612817013534 1.38673251704164 -1.03562017367205 0.301161341898472 -9.69292251189115 5.69662375568056 -1.70152057211529 0.0898166028006581 BTLA other 1 1 1 -1.03562017367205 -1.70152057211529 5.73717318752672e-08 19.9943696695366 4.68731922898857 4.26563003131557 2.63013627164835e-05 -29.1731005584556 11.6508829085852 -2.50393903941467 0.0127809177168072 ZNF17 other 0.000640956988510486 1 0.286711154972387 4.26563003131557 -2.50393903941467 0.000464203062049889 3.99601728367004 1.64518924456902 2.42891041067853 0.0157034163545122 -4.19534478422638 3.84878593684515 -1.09004367950515 0.276527054849793 KDM4D other 1 1 1 2.42891041067853 -1.09004367950515 0.30342326511087 -9.37190909361173 31.809210473405 -0.294628786886973 0.768477900932979 -163.396533785189 105.690555873753 -1.54598991777814 0.123143937282623 GPAT2 other 1 1 1 -0.294628786886973 -1.54598991777814 0.0280975024529085 110.505578771578 54.7915542340576 2.01683599445859 0.0445475097504005 293.978703340284 172.115417947794 1.70803235901536 0.0886001345876306 TOR3A other 1 1 1 2.01683599445859 1.70803235901536 6.90826944731411e-06 448.720941848849 91.8069008610165 4.88766026998508 1.61682213063572e-06 -40.6334014822388 257.467301625018 -0.157819657975125 0.874698447091599 PPP1CC other 0.0669065895972371 1 0.0190607160980645 4.88766026998508 -0.157819657975125 7.19175951839319e-10 15.6135980261989 4.44064929112843 3.51606195458666 0.000501671695213074 -25.4594188060159 7.71095987996747 -3.30171848930996 0.00107027788273812 ZNF555 other 8.74589875031796e-06 1 1 3.51606195458666 -3.30171848930996 0.00304664280026476 9.04638691513604 7.83286907260165 1.15492635345829 0.248984976328037 -29.9054296822631 11.3652974050995 -2.63129319157498 0.00891923585429185 PRELID2 other 1 1 1 1.15492635345829 -2.63129319157498 2.95634752506835e-15 363.34045897211 53.2784101403502 6.8196565553471 4.56214587007958e-11 31.0909481648925 98.437746344606 0.315843762371915 0.752326997996865 BACE1 other 4.07769014132677e-11 1 6.23508476063776e-07 6.8196565553471 0.315843762371915 0.0267031490468395 998.862206261612 469.502068538928 2.12749266338705 0.0341483079594937 -1212.01293162815 1085.15085219187 -1.11690732139226 0.264877126576707 THBS2 other 1 1 1 2.12749266338705 -1.11690732139226 4.88187917543753e-14 889.340486896932 116.644862335527 7.62434340518793 2.81717349658054e-13 -541.883249037777 245.034149245788 -2.2114601197657 0.0277104336402826 RXRA other 6.59395420226348e-10 1 3.9826381721159e-09 7.62434340518793 -2.2114601197657 0.000109408320850907 65.5129847619626 32.5463194323483 2.01291531284021 0.0449660335605713 -158.3943615577 60.8577145450614 -2.60269980136075 0.00968252062152239 ANKRD37 other 0.938176351296529 1 1 2.01291531284021 -2.60269980136075 3.25875878160383e-15 87.8382128758195 10.1948130529843 8.61597092750089 3.76038036207139e-16 9.74243356363271 39.3339718239824 0.247684968282116 0.804544277838107 NUDT17 other 4.49187310456272e-11 1 5.46120039983628e-12 8.61597092750089 0.247684968282116 0.0966540566748244 -99.447650497547 50.741765756018 -1.95987760803835 0.050877717818437 -163.505478138643 128.768788441126 -1.2697601656274 0.205092661013444 CYP4X1 other 1 1 1 -1.95987760803835 -1.2697601656274 0.548746414900362 987.845027087575 2762.22319949191 0.35762679397859 0.720859121921285 8548.33605791456 8055.47910296319 1.0611828233494 0.28940957434872 KRT10 other 1 1 1 0.35762679397859 1.0611828233494 0.806038468833282 -1.46532952398384 7.62380937394254 -0.192204376068504 0.847704031540948 -11.8129557123813 18.1871501513482 -0.64952208642241 0.516466917969002 CD300E other 1 1 1 -0.192204376068504 -0.64952208642241 0.0689297586190952 -1.82569712166543 1.9808707878386 -0.921663913100316 0.357400420333584 -13.9212694786653 6.16370653677161 -2.25858732819503 0.0245841441824387 CCDC30 other 1 1 1 -0.921663913100316 -2.25858732819503 0.00710957864252968 17.9793018345652 6.63904019592594 2.70811763507597 0.00713506022115725 -8.69368690627308 13.909049365222 -0.625038180395755 0.532397075876757 GLDN other 1 1 1 2.70811763507597 -0.625038180395755 8.68085798350663e-30 753.210916879851 58.4272483632475 12.8914323022209 8.60158739481796e-31 256.091125551798 343.816189362487 0.744848943927419 0.456921936290238 KPNA4 other 1.31141721556835e-25 1 1.30795737925602e-26 12.8914323022209 0.744848943927419 0.618209300623632 -70.8897012441451 223.525827983936 -0.317143221808085 0.751343701597816 -514.423370554788 526.010945991922 -0.977970847326604 0.328834482462801 TRDN other 1 1 1 -0.317143221808085 -0.977970847326604 0.050185420472688 392.549441456351 198.456648456885 1.97801103923023 0.0487849673316024 -561.036555580767 538.913440553111 -1.04105133285403 0.298637622310927 KRT3 other 1 1 1 1.97801103923023 -1.04105133285403 0.05196313357119 6.2840189288443 3.97601547387944 1.58048150720925 0.114984533896315 -4.34091431904636 5.69774935265404 -0.76186473822762 0.446701875640582 ZNF501 other 1 1 1 1.58048150720925 -0.76186473822762 2.5163789030121e-14 49.7991829541812 11.844655059198 4.2043590721124 3.40187822278542e-05 -66.518476983873 16.9737457359811 -3.91890381878801 0.000108810760509281 ZNF197 other 3.41975892919345e-10 1 0.367947148576471 4.2043590721124 -3.91890381878801 2.86687345543125e-07 1901.11928268866 518.828780756515 3.66425177862454 0.000290397908911679 -1741.16509086474 716.713317028991 -2.42937454836536 0.0156766528687515 RPS23 essential 0.00308303571397076 1 1 3.66425177862454 -2.42937454836536 0.0456622930895396 -41.2206262088773 16.5385347572707 -2.49239892250768 0.0132002610504535 -34.7762209751196 50.4412018831079 -0.689440768197986 0.491051881743299 GNG2 other 1 1 1 -2.49239892250768 -0.689440768197986 0.097718544768981 151.651002313129 71.1107517075591 2.13260299844374 0.0337181899546527 179.947460638812 155.326366055483 1.1585120106044 0.247519000746473 BTN3A2 other 1 1 1 2.13260299844374 1.1585120106044 0.109105678571395 24.5170354711875 21.9411049288148 1.11740204291124 0.2646766927316 -118.918556631294 82.1309670485834 -1.44791375171499 0.148638893485726 PCLO other 1 1 1 1.11740204291124 -1.44791375171499 0.924584541363437 -43.6301467923757 115.58603359356 -0.377469019706951 0.706076092072538 11.0791472802162 280.683548135839 0.0394720223319053 0.968538750460256 KLK12 other 1 1 1 -0.377469019706951 0.0394720223319053 0.00921862030489664 109.977789403586 77.0712261522699 1.42696301712266 0.154571675090451 -288.601743968886 172.217990262733 -1.67579324046576 0.0947615840659049 INSIG1 other 1 1 1 1.42696301712266 -1.67579324046576 9.97882781811416e-08 54.0974433631458 9.28758869939007 5.8247027419182 1.40071635596964e-08 38.5645841932198 53.2391846716617 0.724364665444379 0.469374474986043 C5orf38 other 0.00110136322628526 1 0.000180146130541256 5.8247027419182 0.724364665444379 3.84087383333024e-07 6.97472861194853 2.95269225924658 2.36215900593997 0.018776711976995 -15.3973893286208 5.27780577788774 -2.91738460576377 0.00378353178309654 ZNF396 other 0.00409590785586336 1 1 2.36215900593997 -2.91738460576377 2.94445200325342e-08 59.3250806453227 33.3106311613276 1.78096537282659 0.0758666164366796 -335.913447294702 65.4831409411438 -5.12976992958571 5.03794509429993e-07 TMEM222 other 0.000334195302369263 0.0075755580382988 1 1.78096537282659 -5.12976992958571 0.376301564320816 -49.8017185108696 35.6080775354194 -1.3986073373754 0.162902199438522 -3.08994431434749 122.342140051221 -0.0252565821805457 0.979866097066768 ARHGAP30 other 1 1 1 -1.3986073373754 -0.0252565821805457 0.00068562242248651 179.76312951211 64.4219254963719 2.7904029276839 0.0055810925511512 -463.473021247763 209.539894416325 -2.21186052679262 0.0276846855266339 SEPT10 other 1 1 1 2.7904029276839 -2.21186052679262 0.0215887023400903 279.128363503696 107.020576748058 2.60817472663043 0.0095295494592693 -83.2482951423133 299.908934210981 -0.277578576848096 0.781515121465641 CYP4F3 other 1 1 1 2.60817472663043 -0.277578576848096 2.92255946030642e-07 53.5838623451827 12.0396179863384 4.45062811843244 1.18371882274434e-05 -72.8185577646204 22.8173688803874 -3.19136523349156 0.00155651976091757 SMYD4 other 0.00314087465199131 1 0.132103020618269 4.45062811843244 -3.19136523349156 0.669768942389647 1.67242001015438 2.96348518072972 0.564342288947287 0.572916541791936 -4.3060190215698 7.38578877894986 -0.583014103225146 0.560294431511722 FOXD2 other 1 1 1 0.564342288947287 -0.583014103225146 0.00125821841168541 128.189557859765 45.3427030367774 2.82712651153132 0.00499248271382983 -234.484160898239 109.286764769958 -2.14558607706811 0.032658114330235 GPATCH8 other 1 1 1 2.82712651153132 -2.14558607706811 7.71993362038941e-12 226.566750344465 30.4586562068381 7.43850118685143 9.49788064390298e-13 87.8930632059819 126.195866593343 0.6964813157408 0.486634629351293 CEACAM19 other 9.95871437030234e-08 1 1.33359742121042e-08 7.43850118685143 0.6964813157408 1.38975277176284e-08 197.668959237689 33.5213965907363 5.89679963669279 9.5189519012661e-09 -42.5928337308934 94.4484498411003 -0.450963819973238 0.652324916744861 NF2 ts 0.000160169006945667 1 0.000123041972275766 5.89679963669279 -0.450963819973238 1.57324013570714e-17 1001.40276824369 141.944846329872 7.05487232637169 1.07379982789667e-11 -762.490115083377 328.612643141399 -2.32033103715758 0.0209515051226079 UBE2H other 2.232585076582e-13 1 1.48538730192946e-07 7.05487232637169 -2.32033103715758 0.584276932466867 -10.00626585274 12.810297794503 -0.781111103992744 0.435316438820966 -26.4691007534462 32.5037996359314 -0.814338663476929 0.416058448389883 HPDL other 1 1 1 -0.781111103992744 -0.814338663476929 2.90231249244144e-22 42.5498751748277 4.03488581957038 10.5454967197456 1.66976095053777e-22 2.31402748041278 12.4093926420274 0.186473870814254 0.852191697021088 KTN1-AS1 other 4.27336491387078e-18 1 2.50113492781053e-18 10.5454967197456 0.186473870814254 5.91212699785255e-08 69.3176071827666 14.8364274737823 4.67212253793974 4.39666688415318e-06 -79.5356952279502 32.5192462767745 -2.44580377266479 0.0149912823842889 KATNA1 other 0.000660207221850195 1 0.0505089091651517 4.67212253793974 -2.44580377266479 0.12803780048029 15.1525054379848 9.57921241222557 1.58181119552649 0.114696189976106 -12.4726324445674 18.8947348868955 -0.660111534733301 0.509664640654997 FSD2 other 1 1 1 1.58181119552649 -0.660111534733301 4.77840069897515e-31 621.920991967248 60.620907909347 10.2591830676187 2.03093546411049e-21 -686.322065377797 212.007031362385 -3.23726086331855 0.00133925720039758 ARAP1 other 7.23210945789888e-27 1 3.03320211564901e-17 10.2591830676187 -3.23726086331855 2.47780821281513e-34 55.422014334199 6.61017228540551 8.38435247089767 1.74272249186015e-15 -210.374108854917 22.2879516763499 -9.43891623195455 8.8206265095068e-19 KIF24 other 3.76527736019387e-30 1.35493643812534e-14 2.52049953997733e-11 8.38435247089767 -9.43891623195455 0.00189459736494899 31.5980866493324 9.35164075143435 3.37888157695599 0.000822695986492344 13.0669547350257 33.8213147397082 0.386352654696901 0.699505778204616 PDE2A other 1 1 1 3.37888157695599 0.386352654696901 0.641313642442901 -1.38313913912719 6.09851341274569 -0.226799392821941 0.820725003183743 -15.6268321877022 16.5671214580178 -0.94324365444544 0.346270100448356 CARMIL3 other 1 1 1 -0.226799392821941 -0.94324365444544 0.392509450404222 -0.372333086208554 1.73752409028189 -0.214289452613084 0.830459553582015 8.40609066828942 6.65728585338563 1.26269035961771 0.207631461344916 PRG2 other 1 1 1 -0.214289452613084 1.26269035961771 1.57962350451513e-06 150.453256445575 30.5051404722131 4.93206240379787 1.3098911664549e-06 -48.1717951112458 76.5009332391695 -0.629688986415936 0.529347413894186 PRR5 other 0.0161011023815227 1 0.0155300696694893 4.93206240379787 -0.629688986415936 1.38679947945783e-09 205.400379942383 49.9880496734777 4.10898967421333 5.06477070943648e-05 -664.491967976282 177.58843869544 -3.74175240718159 0.000216885787504363 ZFP91 other 1.66637825451653e-05 1 0.540056500747212 4.10898967421333 -3.74175240718159 0.130586039040757 23.0029779342597 11.3984178236348 2.0180851667468 0.0444217763704798 2.90494261832449 26.7805047499786 0.108472287787138 0.913689472644791 C17orf58 other 1 1 1 2.0180851667468 0.108472287787138 0.478033901103899 5.06752725423076 5.87984291380314 0.861847387510057 0.389418892882379 -10.4370987476114 15.7982475971889 -0.660649143735948 0.509314137744916 BCDIN3D other 1 1 1 0.861847387510057 -0.660649143735948 0.504865712910467 26.5026263131565 24.007286461231 1.10394093709654 0.270456030559775 -14.1446660830417 67.5186407327223 -0.209492755327147 0.834198156518083 CYP27C1 other 1 1 1 1.10394093709654 -0.209492755327147 0.0028908091596349 45.4544565144052 19.0081778258701 2.39131056805149 0.017365650114862 -39.5691259446054 28.6439638217816 -1.38141236983815 0.168115980285187 LYRM7 other 1 1 1 2.39131056805149 -1.38141236983815 0.0835035999013136 47.6249961890671 24.8482409660849 1.91663451163686 0.0561748415930234 93.2496361562048 66.2135933007931 1.40831559665691 0.160008443118848 CFAP73 other 1 1 1 1.91663451163686 1.40831559665691 1.08869306877482e-07 133.421834183267 25.5847140413456 5.21490425758341 3.31424108262144e-07 -30.931762302833 68.4447052716788 -0.451923376396391 0.651631307333635 CCDC73 other 0.00119865106872108 1 0.00403707706274118 5.21490425758341 -0.451923376396391 1.94412440792816e-07 469.062473932433 101.94280527681 4.6012317657805 6.06851094512579e-06 -695.882902483237 296.951518442127 -2.34342261031023 0.019721501092652 BCR other 0.00211073586968761 1 0.069132476686873 4.6012317657805 -2.34342261031023 0.0347290928524521 29.1117058107496 21.8428666780413 1.33277862470386 0.183552632222891 139.042136345862 55.7178426035125 2.49546877353606 0.0130824101570319 MPPED1 other 1 1 1 1.33277862470386 2.49546877353606 0.000347734497447256 18.7954288855386 9.58260809207224 1.96141057893082 0.0507061367459798 -26.5307291749824 13.6366712097132 -1.94554292370743 0.0525933595894839 HYAL3 other 1 1 1 1.96141057893082 -1.94554292370743 0.490032778091155 120.893468565674 101.813785871389 1.18739783155089 0.235951385609749 98.0323154941736 247.045492302177 0.396818879715742 0.69176553832709 VSIG10L other 1 1 1 1.18739783155089 0.396818879715742 1.41240715812493e-18 140.393987043348 22.749658903613 6.17125679282388 2.07462236313539e-09 -116.750004429894 40.9399693538901 -2.85173648814176 0.00463441334087821 ZNF397 other 2.02440317974046e-14 1 2.73808659486609e-05 6.17125679282388 -2.85173648814176 1.92849670148102e-13 42.2263297390101 13.0112830081508 3.24536248366575 0.00129873456198461 -101.76127772234 23.4149237078841 -4.34600082374283 1.87136884898804e-05 ZSCAN30 other 2.57859293955027e-09 0.273556698345072 1 3.24536248366575 -4.34600082374283 0.28485256717296 55.3927443048618 46.4099845633458 1.19355231047869 0.233537234445953 -107.801499876178 123.669592836279 -0.871689615885546 0.384031250839952 TPCN1 other 1 1 1 1.19355231047869 -0.871689615885546 0.998671795691676 1.15115339669218 42.2441796930484 0.02724998816539 0.978277331543569 -3.99398930969107 113.865065276939 -0.0350765118342226 0.972040600426475 LILRB4 other 1 1 1 0.02724998816539 -0.0350765118342226 0.821540266866966 6.27819631037509 40.42583246882 0.155301596206272 0.876683025071959 -49.4436813533218 91.7005279896579 -0.5391864413136 0.590139096470481 TNFRSF4 other 1 1 1 0.155301596206272 -0.5391864413136 0.604793244068899 -23235.737169289 23320.6117050473 -0.996360535614084 0.319830172715277 -11969.4482462943 60819.5338829678 -0.196802696142437 0.844107266131636 KRT16 other 1 1 1 -0.996360535614084 -0.196802696142437 0.148005334505963 31.0861608921664 39.690426079399 0.783215600406503 0.434081592792279 -166.22842997934 96.386485711897 -1.72460307844611 0.0855676808948079 HEXIM1 other 1 1 1 0.783215600406503 -1.72460307844611 0.596868959226639 -3.40869903755806 4.04770698596402 -0.842130877896593 0.400343630357547 -9.12243963369061 16.3488849594372 -0.557985431809205 0.577244489795626 LCE1A other 1 1 1 -0.842130877896593 -0.557985431809205 0.772530731089799 945.168150775539 32275.4789177111 0.0292844035927498 0.976656077912518 -60081.7879468359 84173.5889457778 -0.713784319990667 0.475882459988061 KRT14 other 1 1 1 0.0292844035927498 -0.713784319990667 0.0942821454255624 16.3265132862073 10.468320360833 1.55961154449309 0.119840110891625 -12.4899014234907 19.1733483804253 -0.651419938535203 0.515242980756277 PDZD7 other 1 1 1 1.55961154449309 -0.651419938535203 5.61751915005407e-09 121.042971595048 27.0021428918068 4.48271724507375 1.02794574068294e-05 -106.821874241321 45.1416538872279 -2.36637041496489 0.018558738674484 POFUT2 other 6.60002324939853e-05 1 0.115222438073151 4.48271724507375 -2.36637041496489 0.0437326177816924 -4.27911733095625 11.8489252485284 -0.361139701804407 0.718234068759639 47.1259736331324 21.3792933195451 2.2042811672381 0.0282183072874219 QRFPR other 1 1 1 -0.361139701804407 2.2042811672381 0.0189244682009196 52.6201220315177 28.1485057429243 1.8693753235816 0.0624837863896373 155.310783582122 68.3052843535322 2.2737740579231 0.023641647789653 MAPT other 1 1 1 1.8693753235816 2.2737740579231 0.00629917842150452 14.2622650793534 4.45846358408042 3.19891927126618 0.00151799243754584 7.77714210174569 19.0900005603407 0.407393497824334 0.683992248666163 TMEM17 other 1 1 1 3.19891927126618 0.407393497824334 0.677296170478264 24.3000270677857 82.2693745397581 0.295371481839117 0.767904712835744 -133.493664849258 186.616938278104 -0.715335199907311 0.474931807281447 TNFRSF18 other 1 1 1 0.295371481839117 -0.715335199907311 0.923935628330347 -0.385118982165563 1.82702627453214 -0.210790062263436 0.833218781557792 -10.0104385588124 27.4929030755844 -0.364109913430799 0.716076482893838 FGF3 other 1 1 1 -0.210790062263436 -0.364109913430799 0.0665111182508376 17.7139853168353 7.62177438995319 2.32412879344545 0.0207523376345084 8.89651737909228 29.2026632077948 0.304647467109014 0.760835201790165 RTN4RL2 other 1 1 1 2.32412879344545 0.304647467109014 0.0501955975255203 31.5651148238054 17.0124985730996 1.8554073458508 0.0644691209981642 -48.3177696358925 39.7587575733117 -1.21527362988642 0.225168942294188 ZDHHC17 other 1 1 1 1.8554073458508 -1.21527362988642 2.43022480771565e-13 510.071046388648 113.057889054588 4.51159181065526 9.04751275723892e-06 -489.701174772683 207.431424701512 -2.36078586201367 0.0188355650225806 ZNF395 other 3.24337802837731e-09 1 0.101938326235811 4.51159181065526 -2.36078586201367 1.3263897048351e-11 324.97335621255 45.8455436574276 7.08843936154087 8.80377678456697e-12 -88.9345725271532 112.371055119922 -0.791436659843075 0.42927913844058 ZACN other 1.70029896262812e-07 1 1.21905897135899e-07 7.08843936154087 -0.791436659843075 0.00161968560529296 101.336470343826 38.2303769066364 2.65067934306017 0.00843500421982774 -169.758720265919 96.9790215290672 -1.75046847853623 0.0810018597895712 PPARA other 1 1 1 2.65067934306017 -1.75046847853623 0.26576763012087 -4.12792110887843 6.51060547456058 -0.6340302948793 0.526515424505628 -32.449738778749 20.3751179639944 -1.59261599545544 0.112236732143625 FAM183A other 1 1 1 -0.6340302948793 -1.59261599545544 0.170953584957674 -4.54806674262078 2.82258492186122 -1.61131263311 0.10809745704373 -9.6386900903265 7.19998637218315 -1.33870949083531 0.181615535205075 EFCAB6 other 1 1 1 -1.61131263311 -1.33870949083531 0.0340693730184241 5.69305527513321 6.11821506968203 0.930509177969954 0.352808950273436 -21.0469543541398 11.4105047139501 -1.84452439938161 0.066030840825235 KANK3 other 1 1 1 0.930509177969954 -1.84452439938161 0.57189456365829 24.2870659343011 29.7421138855154 0.81658842501202 0.414778837956582 -38.5275228780303 83.7828636904023 -0.459849677857739 0.645940346221874 EMID1 other 1 1 1 0.81658842501202 -0.459849677857739 0.00567956025821149 152.937601905687 55.4665756309748 2.75729302135393 0.0061639469110448 -89.3593514054599 120.714323062685 -0.740254753025925 0.45968989985519 ESPN other 1 1 1 2.75729302135393 -0.740254753025925 4.10194050013466e-05 59.1254317468701 14.358966551085 4.11766623569455 4.87638910668087e-05 -40.6980592359724 28.1274338707215 -1.44691689341543 0.148899051524143 PTRH1 other 0.369625858467134 1 0.52074959270245 4.11766623569455 -1.44691689341543 5.10023857776326e-08 52.1505585050931 9.9171721531525 5.25861179978763 2.66045130833652e-07 -68.655296439091 46.223443869916 -1.4852916764987 0.138451017647143 TMEM216 other 0.000571277723095263 1 0.00325745658192724 5.25861179978763 -1.4852916764987 0.000679390944301613 326.964787079468 96.4500445815187 3.38999104145691 0.000786743548646036 -286.198485525875 272.911332632859 -1.04868670261814 0.295116197040561 RPS19BP1 essential 1 1 1 3.38999104145691 -1.04868670261814 0.143748204718911 -233.650268598517 231.067495955177 -1.01117756797712 0.312702634894549 -966.243791532166 494.801830120759 -1.95278944561775 0.0517242971017508 TMPRSS11A other 1 1 1 -1.01117756797712 -1.95278944561775 2.45443244086155e-08 140.074145995748 23.7972876844132 5.88613912027855 1.01167354875982e-08 -24.2079376328845 100.308317133077 -0.241335298256159 0.809452272591093 TMEM262 other 0.000279682576636174 1 0.000130698105764281 5.88613912027855 -0.241335298256159 0.0128237168356517 25.6203711092056 8.70780695637222 2.94223002847543 0.00349801368664992 9.81350939104102 53.943782802317 0.181921045971205 0.855760596021391 C3orf70 other 1 1 1 2.94223002847543 0.181921045971205 2.01008899692403e-06 313.437148132305 85.0323849961198 3.68609145970218 0.000267788069089015 -284.619418711052 177.450863649769 -1.6039336910346 0.10972448593856 TEAD1 other 0.0202958686019419 1 1 3.68609145970218 -1.6039336910346 8.52242592047009e-07 63.6999180377038 78.5986780632421 0.81044515769654 0.418286673800211 -460.544745417107 112.587870917655 -4.0905360556462 5.45125363076748e-05 PLCD1 other 0.00886758417024913 0.785416623120978 1 0.81044515769654 -4.0905360556462 3.93374130373714e-07 71.8024242688459 16.6166711017581 4.32110762914776 2.07667068622862e-05 -122.143891356335 51.2080345245152 -2.38524857457399 0.0176510864788676 ENTPD5 other 0.00419140135913192 1 0.22799767464104 4.32110762914776 -2.38524857457399 0.451682337423077 30.6276231219966 26.3302449917969 1.16321071572022 0.245616116359554 8.12021361196157 36.7875848179414 0.220732446887933 0.825442417420004 MITF og 1 1 1 1.16321071572022 0.220732446887933 3.91652285877127e-06 5.46365201315533 1.09836643335032 4.97434357720647 1.07045605475583e-06 0.400789052400312 3.40739408540515 0.117623333948077 0.906439908395913 HEATR4 other 0.0387187449818128 1 0.0127459202439777 4.97434357720647 0.117623333948077 0.142332609693331 519.651687951798 281.481988357487 1.84612767226808 0.0658087698125399 701.883996668061 657.832480530226 1.06696464136634 0.286802270712411 NAP1L1 other 1 1 1 1.84612767226808 1.06696464136634 0.33601842757537 -5.48379688315566 4.51099172512349 -1.21565217081074 0.225019147657445 -12.6825151823959 11.1282427818552 -1.13966916709213 0.255281858289605 LILRA5 other 1 1 1 -1.21565217081074 -1.13966916709213 1.58165070442004e-31 102.961522790484 22.1477907221109 4.64883942973571 4.88788846202349e-06 -280.457738843912 32.9606679489265 -8.50886090289462 6.87826651337094e-16 CMC1 other 2.39540999184416e-27 1.05615782312811e-11 0.0559956502209411 4.64883942973571 -8.50886090289462 0.0657844324063473 -26.5578113942151 13.9482681625153 -1.90402213986585 0.0578154235062576 -60.7924871482501 36.6996721246583 -1.65648583839538 0.0986160249156565 LYPD6 other 1 1 1 -1.90402213986585 -1.65648583839538 0.000160387608441576 7719.52044207088 1910.7695939692 4.04000590465505 6.70727081220877e-05 3148.05912904446 3921.98764592458 0.802669312922408 0.42276537214967 AKR1C1 other 1 1 0.707684143396147 4.04000590465505 0.802669312922408 0.0216809302531799 -12.1702175179307 5.57388673437631 -2.1834346655938 0.0297298784752323 -29.1273318207764 13.0443815037449 -2.23294081152213 0.0262440941454759 FOXD3 other 1 1 1 -2.1834346655938 -2.23294081152213 8.25372665831952e-13 147.174384041918 27.3045554676617 5.39010364831701 1.36912258599269e-07 -199.255362250616 54.6765629261229 -3.64425544670472 0.000312797753323147 SPATA21 other 1.08932684436501e-08 1 0.00169565832275195 5.39010364831701 -3.64425544670472 3.17804384176095e-06 130.065511044606 34.6639973368498 3.75217865904748 0.00020809991332148 -306.430329222494 108.70995990384 -2.81878798864014 0.00512074161703226 RNF220 other 0.031627892313205 1 1 3.75217865904748 -2.81878798864014 2.35913533293285e-05 91.5652973313721 35.7011470106168 2.56477186304805 0.0107801237241978 -170.047989405116 68.8648126569902 -2.46930156119222 0.0140593931017502 SHTN1 other 0.217677417169714 1 1 2.56477186304805 -2.46930156119222 0.501014393340147 -7.22978926289691 8.15159454419999 -0.886917182116355 0.375791650574202 -25.2200098672891 33.0361949607872 -0.763405407227567 0.445785865431155 LCE2A other 1 1 1 -0.886917182116355 -0.763405407227567 0.334326397538319 -9.71676779350867 9.07760000835074 -1.07041153879549 0.285243329746356 -36.2619708637447 36.6238655816375 -0.990118609487409 0.322866560508095 LCE2C other 1 1 1 -1.07041153879549 -0.990118609487409 0.0236215120502906 3.82250899931955 2.47426426274669 1.54490733139239 0.123357017478127 -13.6868181917952 7.61149588364944 -1.79817717844352 0.0730913469465356 ZNF546 other 1 1 1 1.54490733139239 -1.79817717844352 0.00155140063470816 53.0392496055167 20.1494707731213 2.63228995950946 0.00889367399785257 -82.8066448483435 47.0005467137523 -1.7618230135207 0.0790570179282994 TSPYL4 other 1 1 1 2.63228995950946 -1.7618230135207 0.000334811624725848 245.628039864554 264.188591761564 0.929745066684178 0.353203918900248 -2157.9346186094 699.148522856987 -3.08651816897396 0.00220214380736938 MT1X other 1 1 1 0.929745066684178 -3.08651816897396 0.000341183911296771 74.8119042457499 23.8893649165832 3.13159870540626 0.0018990964598121 -87.5145634209317 46.1498341091026 -1.89631371618886 0.0588191020553286 GCNT1 other 1 1 1 3.13159870540626 -1.89631371618886 0.241040945990275 -5.49099489550229 3.97687461337333 -1.38073120963817 0.168328222455777 -14.9109036929094 16.0448269521928 -0.929327797509938 0.353421917869729 LCE2D other 1 1 1 -1.38073120963817 -0.929327797509938 0.182054209447872 42.9482857474659 23.4876503615858 1.82854755951698 0.068409911412152 40.8901154240546 83.4467803563583 0.490014297129666 0.624463807740428 SESTD1 other 1 1 1 1.82854755951698 0.490014297129666 0.000743992507020108 12.9341762747493 37.257895959367 0.347152622060439 0.728704859850626 -274.993058349179 73.2212353190493 -3.75564625686718 0.000205360056516796 FNBP1 other 1 1 1 0.347152622060439 -3.75564625686718 1.16221601332566e-29 47.5593416617239 3.9639775225704 11.9978837899375 1.86284683251808e-27 -108.341784035081 51.8575702430825 -2.08921828630283 0.0375111955257976 DYNC2H1 other 1.75529484492574e-25 1 2.81904611164961e-23 11.9978837899375 -2.08921828630283 6.50247739001634e-11 1697.02930560551 250.768443114169 6.76731603279481 6.29318633821665e-11 -1185.89432782335 1038.9802090465 -1.14140223028086 0.25455867019955 BCAM other 8.18856977724758e-07 1 8.58013025352458e-07 6.76731603279481 -1.14140223028086 6.57645611723702e-05 95.15986698029 25.8826149573899 3.67659400477695 0.000277254094139002 -134.646174772935 90.7771568961504 -1.4832605401706 0.13899249161911 RSBN1L other 0.578399315510996 1 1 3.67659400477695 -1.4832605401706 0.515972781568332 -2.44718859720225 5.52645143656176 -0.442813734146328 0.658199648938183 21.8801421656041 22.6929352592731 0.96418298979913 0.335682249085559 NPSR1 other 1 1 1 -0.442813734146328 0.96418298979913 4.06214187189021e-08 10.7848003539178 9.17080839239745 1.17599233267793 0.240474816934718 -90.7176416879847 20.382261208333 -4.45081341862581 1.1839129680726e-05 WDR86 other 0.000457356553356119 0.173904975880184 1 1.17599233267793 -4.45081341862581 0.107870458279439 9.27714561819811 6.99646478884622 1.32597617485158 0.185799227075903 -17.0221556613559 14.7616476587795 -1.15313385435209 0.249721463053951 EPOR other 1 1 1 1.32597617485158 -1.15313385435209 0.434112882942338 9.29865052403509 10.6379715266386 0.874099963583313 0.382721387305716 -3.64542195543354 16.7617226321757 -0.217484922965842 0.827969496171635 DCC ts 1 1 1 0.874099963583313 -0.217484922965842 0.632878122327228 6.27864507902095 10.9660499618704 0.572553025095833 0.567351944981067 15.8009119633598 17.3401043060342 0.911235116265201 0.362861728932214 PCDHB13 other 1 1 1 0.572553025095833 0.911235116265201 0.000681461538750148 16.6322046957601 4.51639963566401 3.68262466510336 0.000271037421115654 -3.00899220634683 16.4756254141674 -0.182632958124879 0.855202033673392 MAGI2 other 1 1 1 3.68262466510336 -0.182632958124879 0.909693212866228 -3.03820242192329 7.66297144941476 -0.396478368995531 0.692019763798929 -0.287819288539624 16.2683318305863 -0.0176919976514428 0.985895729767238 LUZP2 other 1 1 1 -0.396478368995531 -0.0176919976514428 3.72622235382909e-05 226.090045091081 107.415700427262 2.10481376737082 0.0360893723169578 -615.144971836716 214.460277550057 -2.86833990361286 0.0044012700525445 CHP1 other 0.336999549680303 1 1 2.10481376737082 -2.86833990361286 0.391167449024502 23.8607140400297 36.8490015147435 0.647526745887073 0.517756811542017 -91.1527175360583 88.8730095872299 -1.02565129682697 0.305833087136504 FPR3 other 1 1 1 0.647526745887073 -1.02565129682697 0.479614424794955 38.0613193551577 46.0334400893407 0.826818922967501 0.408977710904663 128.359523139307 109.794178674849 1.16909224777243 0.243267536321921 C11orf96 other 1 1 1 0.826818922967501 1.16909224777243 0.869193462753004 -2.36370930797684 9.6404735656211 -0.245186016214605 0.806470057757286 6.18398951874035 19.9638378608582 0.309759554342248 0.756946059436189 KCNJ11 other 1 1 1 -0.245186016214605 0.309759554342248 0.162842745857888 994.774235753576 520.839911405918 1.90994241026643 0.0570429203583038 483.511926717206 1273.95257462937 0.379536833902844 0.704543381559092 COL4A1 other 1 1 1 1.90994241026643 0.379536833902844 0.414339269404488 -13.6069547546966 10.4028248621517 -1.30800575180328 0.191816076976998 -12.1582756189608 24.693090958091 -0.492375605775549 0.622793598078732 GJA4 other 1 1 1 -1.30800575180328 -0.492375605775549 9.77714352760524e-19 146.640629725856 23.8844703144444 6.1395805640778 2.44852814287626e-09 -168.240570196767 49.5569155731466 -3.39489591414223 0.000772989038659877 HSPA14 essential 1.4032156390819e-14 1 3.22569097542519e-05 6.1395805640778 -3.39489591414223 0.00928664396699254 3.07547321168116 52.955491362214 0.0580765683136619 0.953724000765271 979.512201244613 317.911793494557 3.08108167513258 0.00224212948278648 ATP13A5 other 1 1 1 0.0580765683136619 3.08108167513258 1.50696622655848e-05 128.593563689547 28.7670026234669 4.47017596420164 1.08740734288137e-05 -43.696149361764 64.6071604625953 -0.676336013669293 0.499317402110967 SIRT7 other 0.141624685971966 1 0.121680881668425 4.47017596420164 -0.676336013669293 0.213151936706533 658.633474783742 397.034980332664 1.65888021814071 0.0981227613986716 19.9995212447645 853.649999917321 0.0234282448857278 0.981323322991354 PRR27 other 1 1 1 1.65888021814071 0.0234282448857278 0.0152931451743601 54.2241634104842 24.8616193177855 2.18103908347166 0.029908253523694 -83.8940527981485 69.6082983241216 -1.20523062361771 0.229004783996705 IFT140 other 1 1 1 2.18103908347166 -1.20523062361771 0.438383750976353 1.62961393675483 1.29701048244408 1.25643852444739 0.209885047675523 2.15193995747701 4.19329881902353 0.513185453828002 0.608180183950741 POTEG other 1 1 1 1.25643852444739 0.513185453828002 0.622173737141148 17.3032789240571 18.2187589926897 0.94975068998937 0.342955677591573 11.051943964178 59.6598141416793 0.185249386428392 0.853150793025109 TLR5 other 1 1 1 0.94975068998937 0.185249386428392 1.54588041044202e-12 523.210443707434 81.6890547235786 6.40490265774144 5.44802915099106e-10 -669.520028934474 260.982103484922 -2.56538674489285 0.010767243692438 USP7 essential 2.02819509849994e-08 1 7.29654544192233e-06 6.40490265774144 -2.56538674489285 0.0903168388433718 7.11790271325155 3.23490286037417 2.20034511714155 0.0284966735159308 7.04273162412697 7.63380074431274 0.922572105300742 0.356925304821567 NHLRC1 other 1 1 1 2.20034511714155 0.922572105300742 1.05000275422617e-06 95.8951417528159 20.2041031230235 4.74632014937299 3.14801506480447e-06 -48.51283758376 45.830272644793 -1.05853259830589 0.290623735858278 PLEKHN1 other 0.0108538784704359 1 0.0364949386462782 4.74632014937299 -1.05853259830589 0.0206772150133283 9.49140244345532 4.66231456194507 2.03577049925512 0.0425968043741562 25.1733403342221 12.0291779946672 2.09268998641321 0.0371641843389611 ZNF385C other 1 1 1 2.03577049925512 2.09268998641321 3.8549748396507e-07 459.918999262315 82.6959733530929 5.56156461571069 5.64903524147062e-08 155.02342693014 342.195140045583 0.453026384037743 0.650836756010533 TET3 other 0.00411055967151954 1 0.00071047916231976 5.56156461571069 0.453026384037743 1.05851729719142e-16 76.2319671610839 8.57014330878778 8.89506329292254 4.43891312051248e-17 -21.0075997950328 17.919446584563 -1.17233530041771 0.241937212427661 ZNF286A other 1.48668754390535e-12 1 6.48658374300488e-13 8.89506329292254 -1.17233530041771 0.365180071496975 7.39912710595045 1277.54961868204 0.00579165536723622 0.99538261955327 -3947.85854308064 2897.9483516261 -1.36229430757985 0.174078301005147 ISG15 other 1 1 1 0.00579165536723622 -1.36229430757985 2.62513702534498e-09 64.4587366740779 10.2376376832882 6.29625101690202 1.01558565044223e-09 -16.635560116299 21.538987164232 -0.772346442729871 0.440484697298129 EXD3 other 3.12547726500667e-05 1 1.35154138360852e-05 6.29625101690202 -0.772346442729871 0.000125147287232172 33.5114317374882 7.97275614752634 4.20324303382659 3.43153809795101e-05 -10.748881761948 15.1732172162086 -0.708411512784883 0.479213637282533 C17orf97 other 1 1 0.371017899150463 4.20324303382659 -0.708411512784883 7.55318527526141e-09 21.9925893040094 3.78093007246706 5.81671411067891 1.45493967644424e-08 0.503113920435142 8.55559887890281 0.0588052253917335 0.953143951266558 ZKSCAN4 other 8.81758849034017e-05 1 0.000187061594200435 5.81671411067891 0.0588052253917335 0.0258545240143057 14.5232728788073 7.41779843732942 1.9578953245373 0.0511192349732872 62.5452213142975 30.5812203719321 2.04521665759626 0.0416588240169619 RGPD1 other 1 1 1 1.9578953245373 2.04521665759626 6.16508016693182e-05 122.028370391143 32.5561682009343 3.74824118237726 0.000211362891956989 -131.594526400655 88.6895357599138 -1.4837660979181 0.138858333086524 DHRS4L2 other 0.544068324731733 1 1 3.74824118237726 -1.4837660979181 0.0124000178611379 86.4642654066883 64.4000351798935 1.34261208344314 0.18036740677968 -317.884386299558 146.088955263889 -2.17596453972407 0.0303031746244865 SAMD11 other 1 1 1 1.34261208344314 -2.17596453972407 0.0312840702085985 56.2810510370662 24.699852359294 2.27859868222609 0.023360037909557 -36.3821646270557 56.0282711397673 -0.649353690323538 0.516582980236415 PERM1 other 1 1 1 2.27859868222609 -0.649353690323538 0.000119830190530814 9.10142829291381 5.45901277437624 1.66722971150288 0.0964501283705709 -28.3226020450351 9.90326456265462 -2.85992582202036 0.00451669659364663 VMAC other 1 1 1 1.66722971150288 -2.85992582202036 0.951992311621289 -1.38274073273534 4.57825388390355 -0.302023602840561 0.762830267083008 -0.613651534319573 6.64785921228284 -0.092308142324339 0.926510980176124 ERC2 other 1 1 1 -0.302023602840561 -0.092308142324339 1.02901944153164e-09 71.5633754512632 16.4202643438493 4.3582352849313 1.77052545023772e-05 -80.3902045728043 28.7625343360806 -2.79496248951749 0.00550486653410739 B3GLCT other 1.24233517176115e-05 1 0.195271251906718 4.3582352849313 -2.79496248951749 0.149417194371384 78.9480731249044 46.2540851335678 1.70683460492033 0.0888259212075606 -20.9328849230232 66.1221478869189 -0.316579022188183 0.751770119384385 SPRY4 other 1 1 1 1.70683460492033 -0.316579022188183 0.207217757278913 5.2725483915252 13.5826769373154 0.38818183012511 0.698139590648496 -49.1102104320424 28.9794257209412 -1.69465782051555 0.0911132188271971 TRPV2 other 1 1 1 0.38818183012511 -1.69465782051555 0.448407824797188 -99.5053143108587 327.26783397966 -0.304048562001492 0.761289749645831 -881.986784777789 700.112142963579 -1.2597792991339 0.208672760082476 AMTN other 1 1 1 -0.304048562001492 -1.2597792991339 0.994011843151474 -0.457965122981812 4.26498186733472 -0.107377976560544 0.91455836184845 -0.464438461461351 10.7939887340428 -0.0430275103027092 0.965707215711581 C2orf88 other 1 1 1 -0.107377976560544 -0.0430275103027092 7.26784993594683e-18 252.961143112523 27.4507896147709 9.21507711298796 4.36590184628468e-18 -56.3194358923428 57.8340303705392 -0.973811362125508 0.330890373502004 TMEM203 other 1.03494183087883e-13 1 6.41918548459236e-14 9.21507711298796 -0.973811362125508 0.719934214511384 -7.64943565234382 10.524445813437 -0.726825505869149 0.46786420932778 -13.6762778604385 22.2240800070074 -0.615381057669265 0.538740493171003 SLC18A3 other 1 1 1 -0.726825505869149 -0.615381057669265 0.0305311252573954 24.7276775586802 9.34769176124747 2.64532444910017 0.00856413112425722 9.50775853493709 37.582010048277 0.252986961653292 0.80044072912737 KBTBD12 other 1 1 1 2.64532444910017 0.252986961653292 0.126988275738174 178.346256833397 87.5782638990258 2.03642146913329 0.0425310501685262 115.953315401937 172.670228905245 0.671530443534463 0.502367152257932 THSD4 other 1 1 1 2.03642146913329 0.671530443534463 0.000143576903884737 19.6148700679506 4.76063439795232 4.12022189235693 4.83244738993115e-05 0.882362097044616 10.5818043541914 0.0833848432186445 0.933598004602005 GABRD other 1 1 0.516395328088043 4.12022189235693 0.0833848432186445 0.0783590694183654 617.297140064467 280.277810836802 2.20244741537496 0.0283509977446628 175.392468529518 546.806067413023 0.320758087706145 0.74860440877444 AMY1C other 1 1 1 2.20244741537496 0.320758087706145 1.27855760940419e-08 242.798008547766 40.3320987902719 6.0199695981685 4.98737922887678e-09 -117.343295133949 187.489734065017 -0.625865174534073 0.53186990900205 TCEA1 other 0.000147609476005714 1 6.50753241783842e-05 6.0199695981685 -0.625865174534073 8.78703973481057e-14 21.4242601388784 9.6232166851821 2.22630964673877 0.0266893983200378 -99.7345804437283 16.8912078607363 -5.90452626396018 9.02531740037945e-09 NHEJ1 other 1.18255980751081e-09 0.000137202875120568 1 2.22630964673877 -5.90452626396018 0.122959174654537 -7.58276999746208 36.0683661356381 -0.210233254507466 0.833619840753519 -177.265863419279 92.0992875425512 -1.9247256754009 0.0551527985922953 FANCA ts 1 1 1 -0.210233254507466 -1.9247256754009 9.35790544011569e-10 117.694930449967 20.807238348579 5.65644169006239 3.42975316247112e-08 -103.13496891626 39.4742502820322 -2.6127150782951 0.00940654551811352 SECISBP2 other 1.1326808744716e-05 1 0.000434721213343214 5.65644169006239 -2.6127150782951 0.0588435726484249 -21.9324228451794 49.8128891026908 -0.440296141024165 0.660019892425477 -225.937472392087 94.5494376433483 -2.38962259346639 0.0174442137066409 SEMA4D other 1 1 1 -0.440296141024165 -2.38962259346639 0.479135568397507 8.35209889845044 11.8894502952444 0.702479819591924 0.482895490362894 -5.89434622963832 18.0413867418597 -0.326712481361659 0.744100968256848 FAM69C other 1 1 1 0.702479819591924 -0.326712481361659 0.000225741502129117 357.207022470098 110.011732626854 3.24699024313795 0.00128995858254217 -481.515342238344 258.987542268166 -1.85922202288697 0.0639133943469502 DNAH17 other 1 1 1 3.24699024313795 -1.85922202288697 0.14324222360964 56.7471717548441 35.4744912285549 1.59966132817053 0.110663634662555 -80.05439288188 96.2573452291668 -0.831670483860621 0.406217074192347 MCRS1 essential 1 1 1 1.59966132817053 -0.831670483860621 3.1213912028042e-05 30.0881583509057 7.15427975201825 4.20561669291974 3.42930301341531e-05 -21.5269873864206 21.3532128271017 -1.00813809897021 0.3141899131727 FANCM other 0.284608449871687 1 0.370810534840597 4.20561669291974 -1.00813809897021 1.77538259052491e-05 28.9699975624157 6.22451746590067 4.65417564029983 4.78186622515623e-06 -0.551375192239262 18.8811475345156 -0.0292024195685841 0.976721469826673 ZNF70 other 0.165714210999595 1 0.0548001869402905 4.65417564029983 -0.0292024195685841 0.00477951395653687 76.4909698198734 24.0338465902431 3.18263535271653 0.00160317200582684 -23.3916729435422 50.1086964039966 -0.466818628745579 0.640948308743457 CARD9 other 1 1 1 3.18263535271653 -0.466818628745579 0.0113232843528136 59.0952389060984 20.8061290815804 2.84028031713094 0.00479608139094972 -81.9460915154359 73.037172897885 -1.1219778677634 0.262713023712696 PEAR1 other 1 1 1 2.84028031713094 -1.1219778677634 7.89318877834234e-05 11.3067201757152 2.62188993315359 4.31243128582275 2.15897633981856e-05 -1.70828922925939 6.6498541818442 -0.256891231378194 0.797429393041435 ZFP69B other 0.687417810705835 1 0.236688576134309 4.31243128582275 -0.256891231378194 9.96262996712319e-05 14.2388933674483 3.82292348413574 3.724608516633 0.000231499565167526 -16.0664143095814 9.6960148465398 -1.6570121399221 0.098506358716965 ZFP69 other 0.859019442397835 1 1 3.724608516633 -1.6570121399221 0.028133439903383 8.08821262632732 5.06157373617442 1.59796400248442 0.111044120447387 -19.4460460829604 9.35489894692525 -2.07870188585542 0.0384461833210029 TMEM220 other 1 1 1 1.59796400248442 -2.07870188585542 0.142712190737106 180.339353053933 140.04998237445 1.28767851303088 0.198791269418978 -265.783816941965 304.395005734584 -0.873154328864758 0.383235750719679 HIST1H1C other 1 1 1 1.28767851303088 -0.873154328864758 1.66065350036025e-13 413.264312742088 53.5750789306654 7.71374155653446 1.57497261030407e-13 -196.935474422962 102.348381563758 -1.92416793909224 0.0552229361723056 PLSCR3 other 2.2232829062823e-09 1 2.23457113949941e-09 7.71374155653446 -1.92416793909224 1.10375585041561e-08 572.09096350671 102.624994902256 5.57457726601199 5.69233985280942e-08 136.850307799559 240.289130461367 0.569523505024134 0.569443325494 EIF4EBP1 other 0.000127770777244111 1 0.000715735460808614 5.57457726601199 0.569523505024134 0.439609946898415 2.40025072501572 5.49048998288546 0.437165122329264 0.662289260277606 -16.3817839222968 15.3200848607236 -1.06930112145103 0.2857475495551 CCDC157 other 1 1 1 0.437165122329264 -1.06930112145103 3.53911965864497e-07 74.5896484826153 14.2945703686809 5.21804059575232 3.26871328165634e-07 -27.3847006656387 27.7888440933289 -0.985456630497733 0.32514900962667 FAM122A other 0.00378791977064771 1 0.00398227339104191 5.21804059575232 -0.985456630497733 0.00605674835357739 17.4871294774725 5.4363653129271 3.21669506570685 0.00143154096730069 8.65428620886713 13.4847365220479 0.641783856489678 0.521480269537124 PALM3 other 1 1 1 3.21669506570685 0.641783856489678 0.304621160083761 -1342.06170939663 874.186408083578 -1.53521228079803 0.125719793340828 -875.941218147373 1741.67993616667 -0.502928925090144 0.615360207389443 DMBT1 other 1 1 1 -1.53521228079803 -0.502928925090144 0.32225648207239 5.23555365285497 5.21318290340711 1.00429118829367 0.316004256144706 -10.6887070997308 12.8701009904577 -0.830506855203063 0.406877318650954 CLEC17A other 1 1 1 1.00429118829367 -0.830506855203063 0.28023486617677 263.744144788414 185.52931455617 1.42157666792093 0.156126073060874 -102.103289645594 358.149756070105 -0.285085464711604 0.775763664951436 LDLRAD2 other 1 1 1 1.42157666792093 -0.285085464711604 5.83434985814645e-19 58.2660689475339 6.00930123208009 9.69598073008654 1.28734566411504e-19 0.0172383763749816 28.6884638906005 0.000600881819281705 0.999520947265115 PMS2CL other 8.39504601088692e-15 1 1.9068163976872e-15 9.69598073008654 0.000600881819281705 1.10775194503915e-06 231.925847018187 43.8011682851146 5.2949694288635 2.21684532208529e-07 -30.2149372107871 215.852361845707 -0.139979646052634 0.888764135420445 CYHR1 other 0.0114331078247491 1 0.00272184268645632 5.2949694288635 -0.139979646052634 0.746644392284732 35.5936664484462 50.2341340477843 0.708555390137478 0.479117877241737 -68.3075195519682 277.641289886848 -0.246027957800537 0.805818814999393 COL14A1 other 1 1 1 0.708555390137478 -0.246027957800537 0.055557090936708 52.029506088651 31.2622094052055 1.6642939535805 0.0970356095876525 -43.2698264560573 54.4825742362448 -0.794195705005288 0.427671918018851 DNER other 1 1 1 1.6642939535805 -0.794195705005288 4.25855044336999e-05 5.51961013165645 1.21155216674801 4.55581714361662 7.43915792658507e-06 2.11460711093459 2.86498622750224 0.738086309328666 0.461004622962419 CPSF4L other 0.38292885586783 1 0.0842484635185759 4.55581714361662 0.738086309328666 1.94608227654542e-05 43.2279141161025 10.5495380077551 4.09761205508006 5.31476020238487e-05 -26.9967882923701 23.9301987436931 -1.12814726620209 0.260116242530731 KLHL17 other 0.180829965136601 1 0.565596780737798 4.09761205508006 -1.12814726620209 0.513360434799304 33.2292451479957 32.7722130375694 1.01394572011058 0.311374677684816 -25.7385772538105 62.5439850962553 -0.411527618750209 0.680961183108967 ANKRD19P other 1 1 1 1.01394572011058 -0.411527618750209 0.000163927352258446 29.4935223385765 11.2482471127646 2.62205497824696 0.00915798009917808 -81.0515243921294 32.7210970921013 -2.47704177411872 0.0137638751358167 RINL other 1 1 1 2.62205497824696 -2.47704177411872 0.643471988631042 0.450944208067365 2.41479790189567 0.186742007566498 0.851981252777583 -4.92667069807873 5.69193283575995 -0.865553203145089 0.387383670249012 C17orf99 other 1 1 1 0.186742007566498 -0.865553203145089 0.027680883008112 54.4188341981633 21.1914012094568 2.56796771767402 0.0106905382024555 100.273845574635 134.59918595185 0.744981070023009 0.45683862486357 TPRG1 other 1 1 1 2.56796771767402 0.744981070023009 0.956951138780864 -2.59292976945572 11.8083332608376 -0.219584738352126 0.826335019939751 6.45079486785714 40.4441608599026 0.159498793662761 0.873376847638041 MORN2 other 1 1 1 -0.219584738352126 0.159498793662761 0.341451025392296 -14.5105774883553 10.2046892477764 -1.42195192190856 0.15601413079005 -11.9395920951477 36.6221753147839 -0.326020832802027 0.744621690921556 S100A3 other 1 1 1 -1.42195192190856 -0.326020832802027 7.7990418182784e-05 57.836845087837 13.363563631728 4.3279507384183 2.01667958975749e-05 52.7578458324943 34.4494845065028 1.53145530588522 0.126647967164749 RILPL1 other 0.679842475299328 1 0.221612920118451 4.3279507384183 1.53145530588522 0.0020029992030661 5.6814116932109 4.63772676177692 1.22504235049719 0.221489258315247 -28.5383564332039 9.98343894348675 -2.85856973681624 0.00454381558232177 ZNF490 other 1 1 1 1.22504235049719 -2.85856973681624 0.00206798150597707 16.9969850597558 4.89560793526335 3.47188444918669 0.000587844465876702 25.1931413618625 10.6721688803401 2.36063930812344 0.0188428783019047 CLCN1 other 1 1 1 3.47188444918669 2.36063930812344 0.297192639690972 -23.795435227279 23.0619893727627 -1.03180323443313 0.302948386862231 -76.9354128165339 54.3759968469529 -1.41487820504839 0.158082662086254 NWD1 other 1 1 1 -1.03180323443313 -1.41487820504839 8.51728238103577e-06 400.161930338861 186.462807985233 2.1460683482282 0.0326192953109117 -972.317237365075 327.07665608841 -2.97275033013134 0.0031754044727588 ARL4C other 0.0817999799874676 1 1 2.1460683482282 -2.97275033013134 0.0685553681441106 -28.9202981272544 18.31578211073 -1.57898242905564 0.115331138281124 -74.6077704768043 36.7008717522597 -2.03286098979953 0.0428943406140344 RAB42 other 1 1 1 -1.57898242905564 -2.03286098979953 1.29086711393702e-07 536.807323918141 114.679166267115 4.68094895866079 4.22813180769993e-06 -616.210110087209 287.539140841738 -2.14304775441466 0.0328654544633937 WNT7B other 0.00141479035687498 1 0.0486277439203569 4.68094895866079 -2.14304775441466 6.84474239127127e-08 89.1918095998315 16.7418508513441 5.32747605935523 1.90715177542993e-07 -70.1890913508666 68.1640342364069 -1.02970858660502 0.303941857348561 C11orf95 other 0.000761340696181103 1 0.00234732240519916 5.32747605935523 -1.02970858660502 0.0236742715060085 525.073022857429 217.180220543706 2.41768344070616 0.0161780353771663 -106.073211796517 433.927856756048 -0.244448956537378 0.807039794044798 PLA2G4E other 1 1 1 2.41768344070616 -0.244448956537378 4.10392140999017e-10 52.2598573468588 7.82486904725967 6.67868778777335 1.12074043499731e-10 37.0186862296804 31.868294758531 1.16161490629399 0.246288416943877 GPR89B other 5.03756353076294e-06 1 1.52174136263935e-06 6.67868778777335 1.16161490629399 0.894316777652659 1.32274415688601 3.27655501964233 0.403699662894843 0.686703221438678 -0.822896512670477 6.79152747371109 -0.121165159951981 0.903636265266619 MESP2 other 1 1 1 0.403699662894843 -0.121165159951981 0.125114296976471 127.414130753747 135.177676563154 0.942567841031205 0.346619765817534 -352.998697507759 275.986508550396 -1.27904331034827 0.201817291065117 FAM25A other 1 1 1 0.942567841031205 -1.27904331034827 0.555769351601389 0.584884937238556 2.88487274677451 0.202742023159426 0.839479829953981 -7.40486401673639 7.25567691396073 -1.02056143135158 0.308318784827537 EYS other 1 1 1 0.202742023159426 -1.02056143135158 0.000143376238725567 368.668208119235 98.9264143250324 3.72669130519519 0.000229557321452656 -238.78008790012 271.76949488505 -0.878612546272409 0.380274774751019 C6orf132 other 1 1 1 3.72669130519519 -0.878612546272409 6.72515941176932e-10 239.284650841207 36.5344670676932 6.54955908889669 2.30077848262462e-10 28.0753656982498 103.207431531545 0.272028528194393 0.785775512212584 MAPK12 other 8.18317397224091e-06 1 3.10375017306061e-06 6.54955908889669 0.272028528194393 9.84012933313276e-07 3678.6872712478 766.00466065339 4.80243458063289 2.42743178587325e-06 -1678.1830678953 1737.57786877072 -0.965817473885389 0.3348764234824 AGRN other 0.0101953580020589 1 0.0283208466457832 4.80243458063289 -0.965817473885389 3.10275865483082e-06 159.237486344224 37.040728276836 4.29898367964341 2.28450046934252e-05 -175.350366110203 78.0383600680371 -2.24697656328664 0.0253270812154276 FAM166A other 0.0309220927540439 1 0.249947196350765 4.29898367964341 -2.24697656328664 1.07576550987205e-05 22.3587884639231 4.96480626044118 4.5034563870245 9.37947585125489e-06 4.82305443851967 7.38869770959966 0.652761099192539 0.514378970896146 TMPPE other 0.10232681529903 1 0.105556621230023 4.5034563870245 0.652761099192539 0.306507992621567 3.31687708512905 5.31396218463295 0.62418153721923 0.532955892079105 -13.5721477641532 12.0167306376721 -1.12943762936691 0.2595645092974 ZNF626 other 1 1 1 0.62418153721923 -1.12943762936691 0.26823047560469 46.1468360102974 28.8306313390476 1.60061829613134 0.110448224880519 19.1073362391277 54.2775277152134 0.35203033453147 0.725047225730537 SMTNL2 other 1 1 1 1.60061829613134 0.35203033453147 0.226461123066568 15.9235628970481 10.662704801417 1.493388703299 0.136320781470522 -21.8470078881685 34.6895407556615 -0.62978659884977 0.529283620417226 ZC3H6 other 1 1 1 1.493388703299 -0.62978659884977 0.159435761594376 187.483146460996 101.174116631909 1.85307421208427 0.0647921374062405 -40.3264762171648 437.919945854153 -0.0920864112241083 0.926687005767497 LAMTOR4 essential 1 1 1 1.85307421208427 -0.0920864112241083 4.51152186064297e-13 363.013121446274 46.4214642589129 7.81994121128084 8.14908265591494e-14 80.4048695145063 222.921465655304 0.360686976815564 0.718576759131699 PRKAR1B other 5.98543605251503e-09 1 1.16108129681476e-09 7.81994121128084 0.360686976815564 0.0410636611853896 0.0547529499947014 1.84882564821176 0.0296149883292997 0.97639263071491 -10.113469051567 4.31986747978338 -2.34115261611548 0.0198397271701973 NUTM2B other 1 1 1 0.0296149883292997 -2.34115261611548 0.295755701922196 -9.41103009735233 11.3817469086554 -0.826852870027851 0.408938509191555 -36.7036555513459 23.5697290502431 -1.55723705915776 0.120405726878588 NCR3LG1 other 1 1 1 -0.826852870027851 -1.55723705915776 1.75773827321092e-06 87.9564341960787 23.9683449764639 3.66969159875031 0.000284534105326312 -194.438734035792 73.8362660200348 -2.63337712639792 0.0088658688593683 DCUN1D3 other 0.0178357702582712 1 1 3.66969159875031 -2.63337712639792 0.291977222909169 61.6782021100895 39.2737531934009 1.57046875062741 0.117297422788336 14.7712193056284 106.709604960865 0.138424458707776 0.889992307431691 POTEE other 1 1 1 1.57046875062741 0.138424458707776 0.833633504272821 -3.55975898528453 7.45725217112269 -0.477355318500461 0.633434989511431 -10.2581030809517 21.0376145681522 -0.487607710832431 0.62616162028949 ZNF793 other 1 1 1 -0.477355318500461 -0.487607710832431 1.39098865573069e-12 2843.29223358823 463.42990411277 6.13532318125148 2.52382459525628e-09 -3775.26069619624 976.366054499659 -3.86664476791021 0.000133816581020525 TUBB4B other 1.82706359930227e-08 1 3.32362460949299e-05 6.13532318125148 -3.86664476791021 0.11598399314343 -1.93008731808731 5.36519872286627 -0.35974199983709 0.719278864636332 -23.1804407484407 11.4537237029808 -2.02383446201064 0.0438230874960783 AGAP4 other 1 1 1 -0.35974199983709 -2.02383446201064 9.14345232060606e-06 363.199091542554 74.5684225086548 4.87068224489258 1.81408504482675e-06 102.70433040839 155.033893781958 0.662463722628518 0.508189547336756 COMMD6 other 0.0875759863267648 1 0.0213028006814005 4.87068224489258 0.662463722628518 0.482792988166811 224.035472459409 263.996642600186 0.848630006248613 0.396723553917292 -300.802384785015 514.705559859021 -0.584416428039763 0.559353245302829 PLA2G2A other 1 1 1 0.848630006248613 -0.584416428039763 0.0479951211587976 -42.061780222955 19.5802829105003 -2.14817019831713 0.0324553082443074 -100.122212568579 58.3196963170535 -1.71678213179073 0.0869927163795624 IL17REL other 1 1 1 -2.14817019831713 -1.71678213179073 0.491741356563115 -0.706008434427097 4.18214197608057 -0.168815032694982 0.866048789025218 -9.43855929474379 8.13873141022832 -1.15970890535617 0.247031907255088 HYKK other 1 1 1 -0.168815032694982 -1.15970890535617 0.989090547014927 -0.0622251503589194 1.32498924909059 -0.0469627586802142 0.962572295654689 0.402586011770029 3.25687572197048 0.123611106513593 0.901701045225788 OR7A5 other 1 1 1 -0.0469627586802142 0.123611106513593 0.276149810662501 15.1095246651549 19.7091830867435 0.766623588540187 0.443872298130244 -38.5065648039577 39.3502705680364 -0.978559086077442 0.328539405959616 C15orf62 other 1 1 1 0.766623588540187 -0.978559086077442 0.0167045098470916 -13.8091246839202 6.44718250901585 -2.14188518234272 0.0329573321764324 -30.4435009735426 11.3116099322787 -2.69134996307373 0.0074903801482089 RUFY4 other 1 1 1 -2.14188518234272 -2.69134996307373 0.0229963674576445 11.2707939668926 8.29297385871385 1.35907747436703 0.17508512202846 -42.0274914478175 22.0438601812677 -1.90653955805487 0.0574813932055034 ZNF383 other 1 1 1 1.35907747436703 -1.90653955805487 0.0368020216219687 28.4310351494529 16.3996776897884 1.73363377544646 0.0839615570930698 -50.1648685923461 37.2004486035933 -1.34850171101164 0.178465813121457 HES4 other 1 1 1 1.73363377544646 -1.34850171101164 0.429202870299858 480.755948514755 369.312519209992 1.30175914302379 0.193935049739869 301.756720867864 850.040468474094 0.354991005792403 0.722830180854184 IGFL1 other 1 1 1 1.30175914302379 0.354991005792403 1.22378616088155e-05 18.8056121159121 3.99527184540657 4.70696684570619 3.74924554245093e-06 15.9712419403934 12.6943112957164 1.2581416642731 0.209257763715843 ZNF669 other 0.115904787297092 1 0.0432550458232564 4.70696684570619 1.2581416642731 3.04570248801617e-12 373.050273179955 51.9206058915357 7.18501386442355 4.75305548015865e-12 -144.372180129121 99.087650789591 -1.45701486490673 0.146092832414461 CENPP other 3.96641835014345e-08 1 6.60769772851655e-08 7.18501386442355 -1.45701486490673 0.0113375090129798 246.749882073053 83.6704636307216 2.94906794304476 0.0034235788396148 -140.857160729301 449.776464778969 -0.313171479077995 0.754355684235393 PLSCR1 other 1 1 1 2.94906794304476 -0.313171479077995 1.94363058901226e-22 25.7504845813018 13.5764602771659 1.89670091140114 0.0587705887166616 -153.575782729544 19.1718774576282 -8.01047174795281 2.16445679244731e-14 C3orf62 other 2.86452276208627e-18 3.32179183936889e-10 1 1.89670091140114 -8.01047174795281 0.0452128769574309 21.9075298145601 11.1553767908402 1.96385386395452 0.0504124700319116 -19.2669488401809 24.4007399709337 -0.789605104727635 0.43034310426419 ZNF559 other 1 1 1 1.96385386395452 -0.789605104727635 0.224555781379842 54.1112806738015 32.0504269268356 1.68831700112221 0.0923307496369822 97.3180730880004 113.399326296113 0.858189164491852 0.391434381869401 SBK1 other 1 1 1 1.68831700112221 0.858189164491852 0.0757768527139656 12.0357339990467 12.5682954935601 0.957626593456025 0.338980849191494 -22.2065509195373 17.8854975248327 -1.24159537014305 0.215303775769664 SLC38A3 other 1 1 1 0.957626593456025 -1.24159537014305 3.28346944936225e-21 173.786844428737 26.2740145896452 6.61440008856612 1.57992445728065e-10 -234.690113276174 49.1814322471484 -4.77192514640079 2.78601472318587e-06 GTF2F2 essential 4.80437249830685e-17 0.0414726151693449 2.13826976048363e-06 6.61440008856612 -4.77192514640079 0.440066031119494 16.07582370183 13.3850927097092 1.20102445686977 0.230629928777204 -22.7595147930425 67.8412422304293 -0.335481987722712 0.737481362814457 FAM92A other 1 1 1 1.20102445686977 -0.335481987722712 1.31216726133502e-23 188.841457772184 18.1312308545877 10.4152585826462 5.47051187435952e-22 -149.058183866254 55.6096744133529 -2.68043619098159 0.00774454342139727 FOCAD other 1.9446318812985e-19 1 8.18224461047954e-18 10.4152585826462 -2.68043619098159 0.0669516696736465 10.6645596640592 17.0730628417123 0.624642441894134 0.532655078188013 -84.2478309309146 42.3011247401456 -1.99162153366953 0.0472703715083789 PRR19 other 1 1 1 0.624642441894134 -1.99162153366953 0.0013454785892782 87.7939444726306 29.3139860027892 2.99495075368723 0.00295974947895914 -126.119768009445 101.552601522523 -1.24191567836372 0.215179967780675 ZP3 other 1 1 1 2.99495075368723 -1.24191567836372 0.0138038606951376 393.54273143962 270.253639364505 1.45619771250825 0.146324557272875 -912.232606222205 540.448371063995 -1.68791813439324 0.0924073855022193 C10orf99 other 1 1 1 1.45619771250825 -1.68791813439324 0.816303969764537 18.5159004064391 29.5907866926369 0.625731941457522 0.53194676773409 35.5553877172204 174.902863602104 0.203286481335762 0.839043213590323 H3F3C other 1 1 1 0.625731941457522 0.203286481335762 0.745513834325244 -6.17868096001763 10.6491175899311 -0.580205909817321 0.56218665363873 4.297160321882 21.5252210066754 0.199633737583896 0.841894633615989 JAKMIP3 other 1 1 1 -0.580205909817321 0.199633737583896 0.00436906049899023 -29.3623581732453 9.00736049111838 -3.25981825665773 0.0012363806481047 -14.1795604658221 16.3199980174034 -0.868845722327987 0.3855909282431 PDCD1 other 1 1 1 -3.25981825665773 -0.868845722327987 0.126393249883334 -50.8519804252282 25.8273608037752 -1.96891896201006 0.049825012869751 48.940260493298 81.8214687698886 0.598134709985904 0.550173143369046 SELL other 1 1 1 -1.96891896201006 0.598134709985904 4.4304099751538e-13 64.2820667984817 9.33079113461263 6.88924078045505 2.9988123981301e-11 -12.0079649902865 20.8695785994676 -0.575381286835988 0.565439084679563 BLOC1S5 other 5.87915403702909e-09 1 4.11377084775487e-07 6.88924078045505 -0.575381286835988 0.204836080318759 12.3398816892562 7.56404766567245 1.631386029633 0.103801915027921 20.8178250075096 22.3680194730552 0.930695944385554 0.35271908817098 CERKL other 1 1 1 1.631386029633 0.930695944385554 0.000260599732939055 112.889312089831 32.6698083641494 3.45546294093696 0.000623456408277941 -115.466766297905 63.8434210896853 -1.80859302849233 0.0714527851315101 IER5L other 1 1 1 3.45546294093696 -1.80859302849233 0.00127734041807241 135.768395455853 108.189441636013 1.25491354241965 0.21042873079024 -386.463949490189 204.098225783318 -1.8935193973733 0.0591935382057738 H2AFX essential 1 1 1 1.25491354241965 -1.8935193973733 0.238464651638789 9.99206197160142 6.42554853889601 1.55505197900477 0.120922111626706 -4.22445517282486 19.2962020855045 -0.218926768806921 0.826846658841682 SERPINA5 other 1 1 1 1.55505197900477 -0.218926768806921 0.000107739079789483 62.9390090738327 15.8143937006407 3.97985596319655 8.53610961493438e-05 -26.2865524406545 46.1852643059626 -0.569154530902205 0.56965053895504 C19orf54 other 0.924939999992708 1 0.891511288183746 3.97985596319655 -0.569154530902205 0.0534939558134128 5.96694132485447 5.0115776165948 1.19063133036116 0.234680813479448 -15.25195344657 9.82201606019462 -1.55283328321781 0.121451386254182 LCTL other 1 1 1 1.19063133036116 -1.55283328321781 0.155160413106134 415.449237920282 226.800489141335 1.83178281269661 0.0679160946357484 -94.4360093916608 711.288580635805 -0.132767503883229 0.894460963374885 NCCRP1 other 1 1 1 1.83178281269661 -0.132767503883229 0.0247732951051161 1628.26642802845 622.185110747571 2.61701284698383 0.00929142635973352 -920.149352942871 3078.13007793976 -0.298931276341233 0.765186520267864 KRTDAP other 1 1 1 2.61701284698383 -0.298931276341233 0.0200680051834419 12.4095230799583 4.59262710541761 2.70205326823065 0.00726109100056216 -1.12942831098949 12.5627688775352 -0.0899028169664996 0.928421039795944 C22orf34 other 1 1 1 2.70205326823065 -0.0899028169664996 1.96714506705266e-05 871.538411262728 196.735882207397 4.42999213709251 1.29559450275885e-05 -525.43001825104 367.490815679582 -1.42977727832297 0.15375652833304 FAM83G other 0.182688762377181 1 0.144264447882198 4.42999213709251 -1.42977727832297 0.0185251248616793 -35.0384050439371 69.5115670735766 -0.504065819820314 0.614563075447932 -383.129054488293 135.423088157781 -2.82912655220143 0.00496309363223235 SRSF10 essential 1 1 1 -0.504065819820314 -2.82912655220143 0.787483968796113 -16.5244012610187 52.7014655875136 -0.313547281404898 0.754073087150293 -97.0371519302866 142.148968976452 -0.682644078455196 0.495335078160725 HBA2 other 1 1 1 -0.313547281404898 -0.682644078455196 0.00913473060073836 3.61485114680282 3.91838598825309 0.922535747534766 0.356944230491243 -15.6502365125429 7.09645889352599 -2.20535858057607 0.0281396781792059 DUSP28 other 1 1 1 0.922535747534766 -2.20535858057607 0.013356967841048 110.045772877042 39.5601837087553 2.78173058262839 0.00572770242985596 14.8989914754167 79.1239900620224 0.188299294104581 0.850761392608171 C15orf52 other 1 1 1 2.78173058262839 0.188299294104581 2.55496847885558e-06 402.570819975216 81.4615236007803 4.94185232709495 1.2520207719968e-06 -227.895871604744 200.205782269569 -1.13830813986127 0.255846001313931 NBR1 other 0.0256212239059637 1 0.01486023454283 4.94185232709495 -1.13830813986127 0.0422584943593708 83.1681003404771 35.4516219378165 2.34596037626592 0.0195919952192388 -39.7009863809328 146.705403435456 -0.270617069659602 0.78686112314491 RALGAPA2 other 1 1 1 2.34596037626592 -0.270617069659602 3.48771486064097e-10 61.6220453868306 10.4901374935746 5.87428386182497 1.07027449281269e-08 -60.0077253315756 22.1008917742781 -2.71517212719059 0.00698595860126212 NDOR1 essential 4.29093559304658e-06 1 0.000138204545256903 5.87428386182497 -2.71517212719059 0.703127738076943 -2.43803097612368 9.72031475977743 -0.250818109945599 0.802117232565511 -19.1758098574222 22.874278146046 -0.838313223918583 0.402486464123027 NKAIN2 other 1 1 1 -0.250818109945599 -0.838313223918583 0.225756170383315 -2.99562986326022 2.61279901718872 -1.1465213526004 0.252436073305186 -9.35113414761109 6.35885784799868 -1.47056820126183 0.142390510553096 CFAP54 other 1 1 1 -1.1465213526004 -1.47056820126183 0.00628881573753814 66.0977001033048 33.723934449139 1.95996407842004 0.0508730247657429 -223.888704368678 119.741077802321 -1.86977358545488 0.0624340018611459 CLN3 other 1 1 1 1.95996407842004 -1.86977358545488 1.91708655417204e-05 1.57936976277589 2.38308939204826 0.662740461203777 0.507975351550637 -20.7916079449601 5.06773717197308 -4.1027399881642 5.18886266892002e-05 ASAH2 other 0.178212366075833 0.748233996858267 1 0.662740461203777 -4.1027399881642 1.30987419727876e-06 407.191448832504 77.178009211996 5.27600352730028 2.43844729291876e-07 42.7992324125678 191.412288193327 0.223597099311307 0.823213496874484 SUMO2 other 0.0134497882576583 1 0.00298904869165982 5.27600352730028 0.223597099311307 0.190071946477725 4.75013958773461 9.0534586175473 0.524676787998782 0.600171172008071 -23.9327189451691 17.6239463352424 -1.35796594530653 0.17543120361482 NANOS1 other 1 1 1 0.524676787998782 -1.35796594530653 0.0826090518182395 42.4931582572982 19.7527160886987 2.1512564685527 0.0322041974374385 -4.21949605731669 46.1976627399624 -0.0913357041690055 0.927282996031978 IGFL3 other 1 1 1 2.1512564685527 -0.0913357041690055 4.76546510038244e-05 148.161868963961 41.0478313565273 3.60949321968018 0.000355945125208623 -183.580467552276 102.939942501781 -1.78337449089889 0.075473042007606 RTL6 other 0.426270853229209 1 1 3.60949321968018 -1.78337449089889 0.00129106032924128 62.0794301362989 68.3824934290287 0.907826360568857 0.364657410592191 -440.155405471201 144.037878252734 -3.05583094398882 0.00243447651020753 DPYD other 1 1 1 0.907826360568857 -3.05583094398882 0.719313802526819 478.451454137089 602.865796711275 0.793628460508317 0.427999844287874 -403.02947272634 2165.0280428737 -0.186154389109616 0.852441641141979 S100A16 other 1 1 1 0.793628460508317 -0.186154389109616 0.000262531619980226 103.58251050969 30.3579329370033 3.41204095564206 0.000727845234854452 -95.8589034887046 58.9307197297139 -1.62663724333186 0.104801530621586 PTAR1 other 1 1 1 3.41204095564206 -1.62663724333186 0.516886943440498 -13.4874920448046 12.1650162776956 -1.10871138491888 0.268397807662929 -16.1511294921373 23.9525246557752 -0.674297583417501 0.500615115631328 SAXO2 other 1 1 1 -1.10871138491888 -0.674297583417501 0.0122888378164189 2.76784015023507 4.2341282177486 0.653697764425945 0.513781935484559 -16.4069784436665 6.80870057577227 -2.40970773513646 0.0165365786076293 LINC00319 other 1 1 1 0.653697764425945 -2.40970773513646 0.00185393063006603 3.92792921358711 2.70472979997768 1.45224458783998 0.147416448907196 -14.6657707545506 5.30536313296505 -2.76432929980313 0.00603566315309059 RHCE other 1 1 1 1.45224458783998 -2.76432929980313 0.000329918237192719 194.864622617611 48.1068929010953 4.0506590816048 6.41452790155673e-05 142.265488208708 122.713393178464 1.15933138611699 0.247185471247405 PARVB other 1 1 0.678143889752577 4.0506590816048 1.15933138611699 0.375415925094182 -6.23147709258703 8.58298535873553 -0.726026764830119 0.468353037075503 -44.0955660540234 35.5163106225395 -1.24155818217333 0.215308887523642 SLC4A5 other 1 1 1 -0.726026764830119 -1.24155818217333 0.000631068897939728 23.4734751205493 26.1801851205143 0.896612266586148 0.370599865141255 -161.673508328536 53.0292562601342 -3.04876062254106 0.00248958085479717 UROS other 1 1 1 0.896612266586148 -3.04876062254106 0.000126906689567486 4.13137371483297 13.8331672451412 0.298657107343517 0.765396141391999 -109.142987996741 30.7865879934585 -3.54514725762829 0.00045112696256074 ZBED6CL other 1 1 1 0.298657107343517 -3.54514725762829 2.95780894290262e-12 220.799759024507 46.8188195092446 4.71604712248051 3.60058497637196e-06 -232.037003927031 67.5842581263547 -3.43329956353471 0.00067497975264075 SMIM15 other 3.85313770991924e-08 1 0.0415939576470489 4.71604712248051 -3.43329956353471 0.0437066549318575 -14.9622639275157 5.9650087555869 -2.50833897159026 0.0126275281953381 -6.55670710364784 25.2019445111335 -0.260166714546621 0.79490355048624 FAM221A other 1 1 1 -2.50833897159026 -0.260166714546621 0.00108582521886333 224.350060850224 61.345458094377 3.65715845670388 0.000298073089472045 -33.3723811569196 161.462588000872 -0.206688010951115 0.836384971200124 TMEM120B other 1 1 1 3.65715845670388 -0.206688010951115 2.39211677727445e-11 18.1964373603729 2.50184014900413 7.27322141968829 2.78425920600841e-12 8.41974235971204 8.44333755957307 0.997205465292066 0.319427772695375 FSIP2 other 3.04899204431402e-07 1 3.88487687014353e-08 7.27322141968829 0.997205465292066 3.89898710922411e-07 135.894865164836 25.3944684976592 5.3513569373331 1.66737507014124e-07 105.843156919029 81.5511445842992 1.29787457255881 0.195265167706338 RBM34 other 0.00415515056230014 1 0.00205704062403325 5.3513569373331 1.29787457255881 0.0080040561322067 17.9007777943728 8.95786957889023 1.99832980785488 0.0465374612463677 -40.558332050413 18.8716907046149 -2.14916261003021 0.0323806906457482 NOXA1 other 1 1 1 1.99832980785488 -2.14916261003021 0.174903309222764 12.217673825992 9.35506298604286 1.30599589165995 0.192500844173928 -9.69134737895886 16.4408190025916 -0.589468649793615 0.555966808716418 TMEM198 other 1 1 1 1.30599589165995 -0.589468649793615 0.524174729191749 -4.4923311859599 5.37940273371859 -0.835098505973823 0.404287241211633 -10.5358222082138 9.8013318254042 -1.07493781415561 0.283214936800375 BCL2L15 other 1 1 1 -0.835098505973823 -1.07493781415561 0.74021506454235 2.98976192808856 3.86493766127825 0.773560194267081 0.439769214386663 1.88054681878226 13.0905725363857 0.143656575260953 0.885863229205851 FZD9 other 1 1 1 0.773560194267081 0.143656575260953 0.0026925898273353 15.2678256470075 4.49918981612016 3.39346110544267 0.000776907000959221 2.50309579031222 13.2723953701677 0.188594124911198 0.850530484814469 SPRED3 other 1 1 1 3.39346110544267 0.188594124911198 0.00328670144251475 251.181504987121 73.8620618186084 3.40068363653287 0.000757371136545096 -56.5086615853913 250.148457523833 -0.225900499826218 0.821423022198409 PRELP other 1 1 1 3.40068363653287 -0.225900499826218 8.67446488872753e-08 38.0066345458184 9.6050529292121 3.95694170827813 9.36091193407488e-05 -66.5233440573866 23.8744880691987 -2.78637782157141 0.00564917745121079 ZNF548 other 0.000960957220373236 1 0.973347622905106 3.95694170827813 -2.78637782157141 5.93430842071768e-07 120.617152598035 33.1768538330786 3.635581396744 0.000323380240636988 -263.5483829257 78.802100357093 -3.34443348250143 0.000923096237175002 MTF1 other 0.00623873844270049 1 1 3.635581396744 -3.34443348250143 0.0211579014393158 13.0050573916987 5.54027755578889 2.34736567992159 0.019517606642431 16.6936287307588 10.2303194877771 1.63177980420884 0.103712633222187 SHISA6 other 1 1 1 2.34736567992159 1.63177980420884 0.00463023369793222 51.9097395454031 26.3397948039965 1.97077235915015 0.0496114994552294 -118.737192109012 59.6053019065448 -1.99205755714785 0.047214210816847 TMEM201 other 1 1 1 1.97077235915015 -1.99205755714785 0.0185871079764065 21.3996093857154 14.0357603044054 1.52464910497216 0.12834051796779 -36.7408494209353 25.3305911009326 -1.45045369350195 0.147917665741818 NHLRC3 other 1 1 1 1.52464910497216 -1.45045369350195 0.0930422692052922 23.1435150044404 10.7257140096465 2.1577598455101 0.0316926350938596 37.7932361632884 65.3129379208166 0.578648539882065 0.563234660435066 ZDHHC11 other 1 1 1 2.1577598455101 0.578648539882065 0.00135565482641619 5.3610698221726 1.47661608334605 3.63064569229415 0.000329221391994915 -0.993411101388995 3.54706738532767 -0.280065471972201 0.779608796739962 LINC00910 other 1 1 1 3.63064569229415 -0.280065471972201 0.000298435637548372 21.460780330158 10.9013649041776 1.96863241610543 0.0498580922742746 -91.2350924509239 31.328729038775 -2.91218620257476 0.0038412961925346 SLX4 other 1 1 1 1.96863241610543 -2.91218620257476 0.507090299856696 3.96925242127275 4.19581918079416 0.946001781831188 0.34487047339569 7.00912949069978 8.83940105792965 0.792941676111871 0.428406740204415 ENTPD8 other 1 1 1 0.946001781831188 0.792941676111871 8.8825930670047e-16 1762.93595446095 437.559206970384 4.02902264739747 7.002834944592e-05 -2803.40442196589 626.777201947012 -4.47272876750691 1.07419295742112e-05 RPL14 essential 1.23503574003633e-11 0.158003042107073 0.737678633063321 4.02902264739747 -4.47272876750691 0.0726678806938834 5.69947331601684 2.79926178088025 2.03606299165939 0.0425724356124487 -10.5843847098529 9.29213048765208 -1.13906974551401 0.255531391135151 FAM78B other 1 1 1 2.03606299165939 -1.13906974551401 0.0006622756196733 8.79197958582974 2.55332335876618 3.44334749284485 0.000653843922996351 -3.72565941931022 5.47139157799037 -0.680934523914782 0.496422867488704 ZNF563 other 1 1 1 3.44334749284485 -0.680934523914782 0.0169908512737253 42.5846037437435 17.9067359234654 2.37813323018516 0.0179910427425023 -53.5877740488896 44.0851756097012 -1.21555088094278 0.225057697755586 FBF1 other 1 1 1 2.37813323018516 -1.21555088094278 0.000169419729953805 81.9212638407845 20.9861535470713 3.903586412681 0.000115599316454298 16.6450226716153 46.1808193034939 0.36043151513243 0.718762255093084 KLRG2 other 1 1 1 3.903586412681 0.36043151513243 2.38040691572863e-13 340.061952780762 43.8989338932337 7.74647406262357 1.2965065994771e-13 -171.933974176294 126.949248630647 -1.35435204249635 0.17659172382563 MSL1 other 3.17760519180614e-09 1 1.84155797389727e-09 7.74647406262357 -1.35435204249635 0.445054296486185 3.61670856025672 15.8999680917515 0.227466403667375 0.820210072848522 -50.962352499651 43.0357000628681 -1.18418783533679 0.237240065709865 LRRK2 other 1 1 1 0.227466403667375 -1.18418783533679 7.09222304687497e-07 742.369862518963 169.507616956332 4.37956639264304 1.61469933014376e-05 -922.335469901731 402.551002731011 -2.291226362981 0.0226018922791099 GJB3 other 0.00741420997320309 1 0.178618039900503 4.37956639264304 -2.291226362981 0.00212807301534088 43.5887733754319 12.6395366300368 3.44860532876236 0.000641187890058666 46.2519114054562 38.4898452421019 1.20166529936742 0.230407486604855 HACD4 other 1 1 1 3.44860532876236 1.20166529936742 0.95325748640189 1.69403865498214 8.44150866275849 0.200679608664711 0.841076590558095 -6.99407770459999 28.9816820371758 -0.241327528734476 0.809455836230192 CFAP126 other 1 1 1 0.200679608664711 -0.241327528734476 0.0122212254113707 14.4961019306908 9.08969557047284 1.59478409571606 0.11174766474815 -45.8806369685468 19.3815803028433 -2.36722889731629 0.0185165024100777 USP32P1 other 1 1 1 1.59478409571606 -2.36722889731629 1.50621306904406e-05 127.431097422488 31.2808845721713 4.07376898592744 5.8381917689411e-05 -116.393701305196 59.6978658791444 -1.94971293514628 0.052083499077219 FAM120AOS other 0.141568966359451 1 0.618789945590067 4.07376898592744 -1.94971293514628 0.887831928796476 -2.72321369899462 6.17306918950081 -0.441144204835136 0.659406507801746 2.06153683413434 12.3268174307371 0.167239990834444 0.867286853231469 C9orf152 other 1 1 1 -0.441144204835136 0.167239990834444 2.4723006316629e-14 739.387239136322 111.929282735284 6.60584273451476 1.68329378781103e-10 -761.514600072065 253.896424575689 -2.99931202790549 0.0029216245653226 NOC2L essential 3.36109270874571e-10 1 2.27699150677198e-06 6.60584273451476 -2.99931202790549 0.967329877566599 -0.465028510441608 3.59232334954822 -0.129450627126896 0.897082418060687 1.32024526024161 7.68768784355207 0.171735024510516 0.86375440036352 AADACL3 other 1 1 1 -0.129450627126896 0.171735024510516 3.08970306634684e-30 644.614062965535 54.4709087184451 11.8340978355526 5.08230264352407e-27 -446.121320163598 114.760713019283 -3.88740456926787 0.000123353053984976 NELFB essential 4.67132206600978e-26 1 7.68545805753709e-23 11.8340978355526 -3.88740456926787 0.00422974765927415 45.4586424208604 40.7194440605211 1.11638661749152 0.265096873023022 -245.777919474485 90.8993423071129 -2.70384706023613 0.00722173392455625 ZNF292 other 1 1 1 1.11638661749152 -2.70384706023613 4.27270151667522e-32 79.693429370691 9.77133350455409 8.1558396644172 8.18709945707464e-15 -177.632532920747 31.5715493101224 -5.62634830416113 4.04874665992015e-08 KCTD21 other 6.47527914852129e-28 0.000613304144044704 1.17722303093276e-10 8.1558396644172 -5.62634830416113 8.55093679070594e-11 9591.61364183099 1375.58749580308 6.97273977198472 1.78643860472228e-11 1215.94637177639 6805.43004409371 0.178672966131168 0.858307563007666 SBSN other 1.0719454360829e-06 1 2.45956867098164e-07 6.97273977198472 0.178672966131168 0.0014670901486837 21.4650602409639 7.78701087422607 2.75652115910231 0.00617816842438232 -29.899093811142 17.4277811525193 -1.71559956769481 0.0872063332869405 ADAT2 other 1 1 1 2.75652115910231 -1.71559956769481 0.0155375278316943 -3.89205573638374 2.2673294747026 -1.71658145841123 0.0870294530838773 -17.7198757514612 6.55587143490075 -2.70290165501537 0.00724300720990827 KIR2DL4 other 1 1 1 -1.71658145841123 -2.70290165501537 0.00138600043297857 18.0213982980314 5.59531763800674 3.22079986587701 0.00141055070758459 -12.2308033338122 16.0950025974269 -0.759913100962629 0.447869526480595 ZNF567 other 1 1 1 3.22079986587701 -0.759913100962629 0.0130343075758326 168.166019823061 66.3585196835822 2.53420390667134 0.0117483513945628 -319.631705668191 285.801566315279 -1.11836932802388 0.26425076780911 NDUFA4 other 1 1 1 2.53420390667134 -1.11836932802388 0.156480843062753 35.054402138126 18.3742434324948 1.90780111665074 0.0573118182939726 -0.887457876592998 51.5302382019918 -0.0172220798420197 0.986270180351463 ALKBH2 other 1 1 1 1.90780111665074 -0.0172220798420197 0.187302249302143 16.3725163661277 8.9233761474359 1.83478944466913 0.0674888635308309 3.21302569595785 20.5078258697196 0.156673150843453 0.875603779586917 RNFT1 other 1 1 1 1.83478944466913 0.156673150843453 0.725231244230025 8.17502355384338 16.7021871458645 0.489458265701899 0.624853685679437 -19.5436424353935 31.5402823172701 -0.619640694360309 0.535936691009298 RNF222 other 1 1 1 0.489458265701899 -0.619640694360309 0.684369664147306 3.21380859374999 3.69184327088528 0.870515988339705 0.38467103887366 1.97831845238095 8.45849537582173 0.233885385577664 0.815223516412976 CGB5 other 1 1 1 0.870515988339705 0.233885385577664 0.0664163522079936 -2.36074400686057 5.17189170958798 -0.456456580961289 0.648374270080613 43.0341605666958 20.3617213647815 2.1134834229256 0.0353404198559084 RELN other 1 1 1 -0.456456580961289 2.1134834229256 3.99302409603396e-05 -81.7996169680148 39.5637066101963 -2.06754179465413 0.0394917364275403 -627.81955147055 139.271129042349 -4.50789446303438 9.21585499267163e-06 FAM111B other 0.360250633944184 0.135777191607031 1 -2.06754179465413 -4.50789446303438 0.645410960834543 40.43356191293 52.2030851848216 0.774543530708532 0.439181341965198 171.882061209345 326.356275949517 0.526670004151944 0.598787641530637 APOD other 1 1 1 0.774543530708532 0.526670004151944 0.000810995467856349 1223.39719025033 447.038466882945 2.73667095984085 0.00655315663334709 -2246.13853430739 1155.46562830486 -1.94392501108199 0.0527807571829756 H1F0 other 1 1 1 2.73667095984085 -1.94392501108199 0.0190467730767968 -99.8990052733307 161.343362228037 -0.619170221159375 0.536244776247072 -1482.08533412354 523.515491241012 -2.83102479090009 0.00493352841600008 LITAF other 1 1 1 -0.619170221159375 -2.83102479090009 3.13741617311126e-08 108.005768104023 19.4815814717928 5.54399386212068 6.20507072136353e-08 -55.070520511976 67.4901489018008 -0.815978648855916 0.415121216411713 TMEM120A other 0.000355532000736967 1 0.000778984578359977 5.54399386212068 -0.815978648855916 0.0100150594610262 79.7551020408158 38.1821558012144 2.08880563098743 0.0375251175566467 -186.586514605842 104.509037297802 -1.78536248567823 0.0751615179533378 ARID2 other 1 1 1 2.08880563098743 -1.78536248567823 0.24404868102522 15.7336921512261 27.1385585156763 0.579754158355084 0.56248836264537 -69.1719629341727 56.7298571412215 -1.21932200114621 0.223619992191137 FAM25G other 1 1 1 0.579754158355084 -1.21932200114621 2.69907463021523e-11 871.477449043196 151.204343472417 5.76357417405916 1.93731429024646e-08 -719.028184828113 419.468168014114 -1.71414243000179 0.0874708760856691 SF3B3 essential 3.43646181919003e-07 1 0.000248228080009279 5.76357417405916 -1.71414243000179 6.21336764289631e-06 87.5459327987346 18.652999802792 4.69339697229989 3.9896435787548e-06 -23.4029902853132 44.7479971124256 -0.522995257788078 0.601339483646127 BLOC1S3 other 0.060400146856595 1 0.0459606940272554 4.69339697229989 -0.522995257788078 0.874508524109943 11.3495511399472 21.9113533530839 0.517975816329477 0.604834184733809 2.18016797799065 52.1240403759834 0.0418265345944898 0.966663148698745 SP6 other 1 1 1 0.517975816329477 0.0418265345944898 0.434643909344481 13.1975279443223 17.4120674636552 0.757952952564075 0.449038710050121 -27.8901509445332 40.6581997651822 -0.685966203757429 0.493232660363469 PLAC9 other 1 1 1 0.757952952564075 -0.685966203757429 0.1503243779617 450.002827765164 412.780783387736 1.09017387890963 0.276464545236048 -1821.61387577602 1424.22698565961 -1.2790193516326 0.2018257170577 CLDN4 other 1 1 1 1.09017387890963 -1.2790193516326 0.0227058287310985 6.84289720634234 2.56146232394251 2.67148071723733 0.00793808874060275 10.7178837234386 7.48824949601657 1.43129361930851 0.153321966752622 ZNF573 other 1 1 1 2.67148071723733 1.43129361930851 4.94723669086758e-08 1077.04784160254 189.466069611484 5.68464761955065 2.95322674041275e-08 -381.439170949546 469.902428031187 -0.811741221571705 0.417543530238625 JPT1 other 0.000554436815945529 1 0.000375414183241269 5.68464761955065 -0.811741221571705 0.0489596019791339 3.65651610392522 3.69588723975385 0.989347311410059 0.323240724252121 -19.7621793561069 10.4264478997212 -1.89538945057552 0.0589418009580775 ZNF527 other 1 1 1 0.989347311410059 -1.89538945057552 0.419813914065884 116.954648038883 96.7535157423061 1.20878964595334 0.227636087580201 -190.899335220667 347.46385675125 -0.549407748493771 0.58310885222408 S100A13 other 1 1 1 1.20878964595334 -0.549407748493771 1.39993325455583e-05 1.48232496997533 29.7669834421175 0.0497976213430476 0.960317824371113 -255.439796248967 60.86999400528 -4.19648137679806 3.60469015183053e-05 ZNF33A other 0.131957708574432 0.522644025113908 1 0.0497976213430476 -4.19648137679806 0.266158294360593 11.0233071300511 16.6967642886148 0.660206189624873 0.509596451144354 -60.3825990630882 45.3404345928809 -1.33176048278481 0.183886711213976 KRT77 other 1 1 1 0.660206189624873 -1.33176048278481 0.438322404996146 19.6198283629057 21.3689650248549 0.918145934540362 0.359242716674603 43.9884056616586 37.6857352777893 1.16724286623071 0.243992329703848 PCDH18 other 1 1 1 0.918145934540362 1.16724286623071 0.477252352298105 12.691029297626 10.4233181539756 1.21756134756238 0.224296262123043 7.73252053674315 33.7515385109473 0.229101275908804 0.818937938735735 ZNF600 other 1 1 1 1.21756134756238 0.229101275908804 0.0127867791000476 166.254892228159 67.0739464797608 2.47868063463846 0.0137020157843563 -272.009496471601 219.012054421409 -1.24198413274649 0.215151894557468 PAX8-AS1 other 1 1 1 2.47868063463846 -1.24198413274649 0.0105331932558826 14.4943884141788 8.69234826891702 1.66748822823969 0.0963956424484234 -30.0560684530511 16.9328397055822 -1.77501641636297 0.0768457000278057 C15orf61 other 1 1 1 1.66748822823969 -1.77501641636297 3.06542810151773e-05 -7.56940853739153 3.09515879034219 -2.44556387898751 0.0150010716459978 -26.1461929139063 5.67880050589037 -4.60417528081609 5.98198823077881e-06 NUGGC other 0.279934894230599 0.0885812817213726 1 -2.44556387898751 -4.60417528081609 3.24762019950566e-10 236.359692595406 67.9782661720819 3.47698913057122 0.000577396698182756 -765.789170708903 158.565736575219 -4.82947443280495 2.12839019067129e-06 TSPYL1 other 4.00106808579098e-06 0.031747068084053 1 3.47698913057122 -4.82947443280495 8.33430853817945e-06 84.4369550838793 43.1678682016835 1.95601401230618 0.0513359688954322 -321.534614985159 84.1000464695647 -3.82323944495703 0.000158380882987067 PNRC2 other 0.0801260422860572 1 1 1.95601401230618 -3.82323944495703 0.000397791629105864 247.337057279754 84.2775683573119 2.9347910968565 0.0035798938814777 -417.642680003164 200.14451420615 -2.0867056069945 0.037708476299724 GJB5 other 1 1 1 2.9347910968565 -2.0867056069945 0.00161201820459852 4.13931145042258 5.3837013312037 0.768859785447479 0.442543633050921 -19.9518308779095 7.77084078197175 -2.56752537308415 0.0106966328834177 FHIT other 1 1 1 0.768859785447479 -2.56752537308415 0.00218428734220915 13.941674919746 4.06723847118347 3.42779874318244 0.000688045091873725 5.09096148114574 9.20346587673921 0.553156989913182 0.580542150053629 ZKSCAN3 other 1 1 1 3.42779874318244 0.553156989913182 6.23766303147744e-05 466.966352164538 115.948984164844 4.02734319345702 7.06016625081446e-05 -265.823796694737 300.51634283258 -0.884556873643407 0.377063983735029 RRP7A essential 0.549912372855051 1 0.743294302885747 4.02734319345702 -0.884556873643407 0.0108616947043885 16.4911825878081 24.8411367836166 0.663865858131116 0.507258705031968 -112.39450742596 46.6201526725976 -2.4108567000044 0.0164837300538993 LIN54 essential 1 1 1 0.663865858131116 -2.4108567000044 0.0687472559394468 -144.461169111673 133.906619232766 -1.07882022516423 0.28148037901679 -629.553492758891 271.234461999979 -2.32106749310838 0.0209111983888008 FAM53B other 1 1 1 -1.07882022516423 -2.32106749310838 9.67756886720724e-06 13.745552258859 2.80972097853419 4.89214137769295 1.58733281525339e-06 13.3256578775495 6.17785482207967 2.1570040509731 0.0317543494642839 FAM180A other 0.0924691705261652 1 0.0187210032230985 4.89214137769295 2.1570040509731 0.637814567770685 417.7593614363 838.164492483246 0.49842168832349 0.618529253712053 -2456.52373489712 3010.03911760531 -0.81611023608605 0.415044168462569 S100A14 other 1 1 1 0.49842168832349 -0.81611023608605 6.95185686837369e-08 110.455860167806 43.4043284787063 2.54481209683947 0.0114029389826894 -378.809261268378 90.4730674473439 -4.18698372848747 3.65823294459498e-05 KAZN other 0.000772698890919736 0.530187700660151 1 2.54481209683947 -4.18698372848747 4.63902595405282e-05 151.723733990012 44.7584430564462 3.38983493681111 0.000787750370153992 -197.559362489511 100.515285114904 -1.96546587181911 0.0502330693702891 SLC35E2B other 0.415656725483133 1 1 3.38983493681111 -1.96546587181911 0.920274175910792 -0.104340624587627 5.58168285555983 -0.0186933989779973 0.985097344132687 7.79894749295823 19.4748931780191 0.40046163137679 0.689083758376568 TOGARAM2 other 1 1 1 -0.0186933989779973 0.40046163137679 4.15058073984022e-05 36.1842293049152 10.6576840203175 3.39513061523822 0.000774354235478123 -67.727176439672 29.0579578910487 -2.33076173809638 0.0204008780229669 NEMP2 other 0.37380130143001 1 1 3.39513061523822 -2.33076173809638 0.000448352313703132 94.3566420274119 23.8845957471648 3.95052288203842 9.59739237637078e-05 29.7725238673415 95.3103711569894 0.312374440534935 0.754959427762367 ALG1L other 1 1 0.996497250438578 3.95052288203842 0.312374440534935 0.176885458196724 3.70244314894752 6.40515982012576 0.578040712944276 0.563647019038467 -23.9939536884577 15.0781040038885 -1.59131106154128 0.112536282138754 KIAA0408 other 1 1 1 0.578040712944276 -1.59131106154128 2.56907858996955e-15 87.441158207242 10.1297329757503 8.63212864707973 2.9105901402849e-16 0.400761824505319 57.2795088966433 0.00699660021925928 0.994421939622288 C8orf76 other 3.54943897990193e-11 1 4.23112488693216e-12 8.63212864707973 0.00699660021925928 0.219085629445229 -245.540210333347 233.649911592693 -1.05088937829937 0.294109851853432 -943.926605018535 578.903395801899 -1.6305425255124 0.103980012989763 CXCL17 other 1 1 1 -1.05088937829937 -1.6305425255124 2.59866832061906e-09 526.518323879956 176.140284295423 2.98919878542309 0.00301447328080324 -1243.04376651447 305.455145388175 -4.06948052858891 5.94545602582262e-05 HMGB1 essential 3.09475410302524e-05 0.855194394754325 1 2.98919878542309 -4.06948052858891 0.0450951245009684 6.92226169021446 3.72296467686211 1.85934122159033 0.0639051442671959 -9.1625406870366 8.36076571062979 -1.09589731421219 0.273955585906939 MMP23B other 1 1 1 1.85934122159033 -1.09589731421219 0.0639845657697793 64.43504470461 50.5922217141048 1.27361563737467 0.203726882750013 -152.01733050288 98.5642417474949 -1.54231725225791 0.123987904293239 SH2D5 other 1 1 1 1.27361563737467 -1.54231725225791 0.0223633687772339 2.91363116008993 1.16721484906762 2.49622523429801 0.0130550868547145 -1.82643200970994 3.28388376219366 -0.556180468607656 0.578476179936664 SPATA41 other 1 1 1 2.49622523429801 -0.556180468607656 5.12193555193726e-06 55.2412803950335 31.3147110321062 1.764068023441 0.0786836629386064 -220.710844211746 65.3494844093078 -3.37739228100643 0.000822954305125859 RASSF10 other 0.0501488709890177 1 1 1.764068023441 -3.37739228100643 0.378477747519134 52.0248838273182 46.3188537487848 1.12319022637047 0.262201299927747 -64.7274955199136 109.999192701339 -0.588436096032599 0.556656003153883 GJB4 other 1 1 1 1.12319022637047 -0.588436096032599 2.11006892501063e-05 -0.937752949793594 43.4653948641515 -0.0215747021906619 0.982800659946199 -335.597044469743 79.6094434921178 -4.21554315353267 3.24603698968497e-05 BLOC1S2 other 0.195561187969985 0.47119472942267 1 -0.0215747021906619 -4.21554315353267 0.243278258639648 -42.0552513539057 38.8106198832514 -1.08360163997418 0.27935979166661 -273.721154454501 182.102303325979 -1.50311747548035 0.13379806058035 SYCP2 other 1 1 1 -1.08360163997418 -1.50311747548035 2.31145938555651e-06 308.075577327367 59.322254281891 5.19325472466766 3.6964766062598e-07 -97.0581921774811 357.502641180207 -0.271489440908932 0.7861907789276 IL1RAP other 0.0232486584999274 1 0.00449491555321192 5.19325472466766 -0.271489440908932 0.000691722352916139 -6.64977616073345 10.9248885820294 -0.608681371055062 0.54317020014624 177.900738310616 49.8230743131316 3.5706495587272 0.000411109301432054 PTPRT other 1 1 1 -0.608681371055062 3.5706495587272 0.0409645970578258 473.766818306243 1283.85003067329 0.369020373865461 0.712357346148291 8349.59944275711 3286.75523282547 2.54037762209002 0.011547085355711 MYBPC1 other 1 1 1 0.369020373865461 2.54037762209002 0.00311533553034908 -0.419324892667894 9.19066757611773 -0.0456250744785422 0.963638271491928 -94.2413924544684 28.0975085404076 -3.35408359495427 0.000894482343406885 PAX5 og 1 1 1 -0.0456250744785422 -3.35408359495427 0.918054249481867 -13.8753306961627 35.7356044664329 -0.388277486930326 0.698070501706187 -17.5974545843937 60.5550185183275 -0.290602744660505 0.771544587460867 SPOCK3 other 1 1 1 -0.388277486930326 -0.290602744660505 0.166067133085223 9.31448085879813 5.18650243981108 1.79590792964852 0.0734523994994744 0.641032213898362 10.7633206902688 0.0595571043867458 0.952545559236897 ZNF699 other 1 1 1 1.79590792964852 0.0595571043867458 3.70936616181649e-09 153.851374760621 29.3048532138587 5.25003055425175 2.77709677234824e-07 -169.229819956478 56.0996105646324 -3.0165952713969 0.00276123192113332 TDRD7 other 4.39077672574218e-05 1 0.00339666706225913 5.25003055425175 -3.0165952713969 0.145850990039772 4.71878537657317 5.48853694846316 0.859752866908269 0.390583296495253 -27.4630529843956 18.8870135392427 -1.45407069928414 0.146928684705695 CCDC189 other 1 1 1 0.859752866908269 -1.45407069928414 0.270506363584721 20.4914429576442 12.7629396757461 1.605542569208 0.109363898905307 29.4117398806104 34.3799496634561 0.855491068733978 0.392921433349695 KIAA0895L other 1 1 1 1.605542569208 0.855491068733978 0.934971808707955 -62.6299517418272 759.446000769509 -0.0824679459479243 0.934326166683147 522.120805393104 1753.70915704805 0.297723715072555 0.766107237498783 HLA-DRB1 other 1 1 1 -0.0824679459479243 0.297723715072555 0.483715500183148 -108.061704912371 787.098347732478 -0.137291235871199 0.8908869386143 -2811.5365009728 2363.69061521743 -1.18946891055544 0.235137013472917 SERPINA3 other 1 1 1 -0.137291235871199 -1.18946891055544 0.00675523395142256 2869.43632268633 979.65832521441 2.92901744295218 0.00364526356652261 624.197902447903 2007.72204588051 0.310898564733424 0.756080787125587 AKR1C3 other 1 1 1 2.92901744295218 0.310898564733424 4.35307444597225e-07 285.897537028161 99.4393754943149 2.8750938509716 0.00431496231637401 -925.383477735711 246.82706452891 -3.74911673281001 0.000211217582859132 SPATS2L other 0.00462209444673334 1 1 2.8750938509716 -3.74911673281001 4.9666303583575e-05 31.0621015287514 7.09494794710709 4.37805911478416 1.62828221695153e-05 -22.6802158999109 35.4338199620258 -0.64007256130491 0.522587772120779 ZNF250 other 0.443520091001325 1 0.18007173037267 4.37805911478416 -0.64007256130491 0.019694096673251 13.3954316508499 8.17135489784571 1.63931585622128 0.102130192508374 -42.8140840735702 22.0486524276491 -1.94180048935241 0.0530386524195559 WDSUB1 other 1 1 1 1.63931585622128 -1.94180048935241 3.58712837098425e-06 15.6390423539653 4.3003968981012 3.63665092421366 0.000321793544295365 -26.1620606180243 8.42394394741853 -3.10567838310955 0.00206827518824081 ZNF79 other 0.03553409364297 1 1 3.63665092421366 -3.10567838310955 0.0407795809927778 327.05982905983 136.968488708076 2.3878472497196 0.0175271814002351 -462.203418803418 491.546962800574 -0.940303681605574 0.347771059788657 S100A4 other 1 1 1 2.3878472497196 -0.940303681605574 0.204401953024933 41.774126532341 48.0806443530683 0.868834581865898 0.385592868965052 229.018597227789 128.697368419036 1.77951266635157 0.0761107249048114 PLEKHG4 other 1 1 1 0.868834581865898 1.77951266635157 0.973850036201249 -4.64570771636581 20.4550252130635 -0.227118161330784 0.820477343313807 -4.29248634578827 36.8120498122178 -0.116605469341824 0.907246078465353 FAT4 other 1 1 1 -0.227118161330784 -0.116605469341824 0.230243208158522 -7.15235675486242 4.70031200039137 -1.52167701936954 0.129083748148964 -11.0699579463816 11.1291736025799 -0.994679240497734 0.32064855589108 KIF19 other 1 1 1 -1.52167701936954 -0.994679240497734 0.17461296857431 9.61374966463787 6.67322732826543 1.44064471232943 0.150691062488675 -10.1501990292092 15.6003960139482 -0.650637267165136 0.515761050362319 ZNF681 other 1 1 1 1.44064471232943 -0.650637267165136 0.590360306465034 17.8967251765432 35.7699554125711 0.500328417246323 0.617187754513865 -42.5676667833937 71.1943292198366 -0.597908109393819 0.550324152894598 ACADSB other 1 1 1 0.500328417246323 -0.597908109393819 0.27723184281835 47.6816163360639 77.470955931266 0.615477320021301 0.538679767918803 -246.741319564843 184.010035272505 -1.34091229969842 0.180905940886186 STK40 other 1 1 1 0.615477320021301 -1.34091229969842 0.208277293819664 81.90001958398 46.1439826745282 1.7748797315926 0.076868316748982 -1.52713309546639 151.104772351609 -0.0101064517797814 0.991942653111753 TMEM63A other 1 1 1 1.7748797315926 -0.0101064517797814 0.331620763890578 -10.8190753635546 9.55804717480131 -1.13193366444955 0.258509827774881 -31.9729209101101 32.4594336240895 -0.985011669654695 0.325362504377244 CTSE other 1 1 1 -1.13193366444955 -0.985011669654695 0.0474864330997873 108.502197271736 46.7656015315157 2.32012833617922 0.0209626110156208 -151.068024243292 162.841277017292 -0.927701053506537 0.354261848213325 SEMA4A other 1 1 1 2.32012833617922 -0.927701053506537 0.123446893466656 2.69221731767269 1.45885051474263 1.84543741148671 0.0659336413964682 -2.2393159019966 4.67632081712379 -0.478862761895347 0.632376040167082 HRCT1 other 1 1 1 1.84543741148671 -0.478862761895347 9.39811783712308e-13 100.654387074797 29.3741098936892 3.42663615813673 0.000695839621275307 -217.700881263852 47.7654096077507 -4.55770992129264 7.51908732407526e-06 MPHOSPH8 other 1.23914183682468e-08 0.110989247990675 1 3.42663615813673 -4.55770992129264 4.81286226319408e-29 96.3527561600784 7.81772855407683 12.3249042856357 8.49915487175775e-29 -37.5020413139883 35.2117574154046 -1.06504315793059 0.287664398201543 RNF216P1 other 7.25827757912299e-25 1 1.28872685320463e-24 12.3249042856357 -1.06504315793059 0.936417646076112 1.56264408035563 5.30269092031803 0.294688886046165 0.768423235168297 -2.17829043512271 16.1189540737717 -0.135138447888946 0.892587641350978 GREB1 other 1 1 1 0.294688886046165 -0.135138447888946 0.260171724935601 2.45063894457882 2.8330492304073 0.865018128974236 0.387676837096519 -11.8085858664524 10.5304372930642 -1.12137659033686 0.262968383983787 SIRPB2 other 1 1 1 0.865018128974236 -1.12137659033686 8.04675396658385e-05 48.5647066857884 14.3618683321031 3.3815034062965 0.000811459667618527 -71.7056888915537 35.7709843398736 -2.00457689982056 0.0458611345602524 ZNF766 other 0.700228530172127 1 1 3.3815034062965 -2.00457689982056 0.197961362436653 590.53813181176 383.730324622927 1.53894048481066 0.124807036344559 -567.637201648607 1131.98615574531 -0.501452423925512 0.616397548243953 RYR1 other 1 1 1 1.53894048481066 -0.501452423925512 0.000192363574753786 25.7006646490398 23.09807083139 1.11267580901661 0.266690745899376 -121.399347758391 38.989132052708 -3.11367146091571 0.00201629750055607 SRGAP3 other 1 1 1 1.11267580901661 -3.11367146091571 0.0425211610645344 40.4574687716273 17.3272212400865 2.3349080738941 0.0201662224792318 -33.2192350358673 81.3483960100273 -0.408357591116764 0.68328427829341 FAM217B other 1 1 1 2.3349080738941 -0.408357591116764 4.01067648671594e-11 5630.08631223523 854.718666907557 6.58706370905101 1.85048889227993e-10 -360.862743878869 1997.4726857401 -0.180659663811705 0.856749440672627 TUBB essential 5.08393351456113e-07 1 2.50130583569478e-06 6.58706370905101 -0.180659663811705 0.0129912200127428 72.8771029946827 59.8228653069278 1.21821485180923 0.224039749154663 -201.35210509436 109.564450040483 -1.83775033799706 0.0670261367531839 LCOR other 1 1 1 1.21821485180923 -1.83775033799706 5.2472613979388e-36 803.982561371374 64.6392585099421 12.437991708208 3.17141412488937e-29 -829.758874165525 202.720755201882 -4.09311258405288 5.39787899295716e-05 SUPT5H essential 7.99000493064142e-32 0.777888341675056 4.81135236886966e-25 12.437991708208 -4.09311258405288 1.30266300147272e-08 102.087666220772 16.9020727172979 6.03994953330746 4.30190655186442e-09 0.548144119816683 44.163181322535 0.0124117897171729 0.990104861917003 XPNPEP3 other 0.000150327310369951 1 5.62431262590755e-05 6.03994953330746 0.0124117897171729 0.0858636222678035 15.4100780549993 12.7996359667432 1.20394658840601 0.229565659280225 -73.4634020633051 48.7234101739047 -1.50776396399796 0.132674331068059 ZNF107 other 1 1 1 1.20394658840601 -1.50776396399796 0.0022145023432379 21.2478291810576 6.01895142875977 3.5301546178843 0.000476251212385706 18.6469170954822 14.0658108741027 1.32569087288199 0.185887701469001 SFTA2 other 1 1 1 3.5301546178843 1.32569087288199 4.51718144254641e-06 1314.25735030282 280.961523611406 4.67771292456595 4.28599859543651e-06 -1130.14676760926 1126.73405328294 -1.00302885522665 0.316604790398145 PPIA essential 0.0444309966688865 1 0.0492632678559472 4.67771292456595 -1.00302885522665 0.262744390919141 2.77448049872483 5.16308805204066 0.537368425787014 0.591391341806687 -17.8254256329705 13.4656888455183 -1.32376633958115 0.186537484814935 ZNF471 other 1 1 1 0.537368425787014 -1.32376633958115 0.000419185019529714 13.2477746823401 4.77544487365081 2.77414461539209 0.00586283323458768 -26.0045939903579 11.8976506804834 -2.18569150235812 0.0295695537614084 ZNF836 other 1 1 1 2.77414461539209 -2.18569150235812 1.1024547445335e-05 21.2020658489349 4.98518773257352 4.25301252155446 2.77669164789403e-05 -9.20723047127175 11.3214361484367 -0.813256405861823 0.416679538583275 ZNF493 other 0.104766274373019 1 0.302048517457913 4.25301252155446 -0.813256405861823 0.0189974995933092 14.173541057792 8.69745499108686 1.62961936248213 0.104178351733389 -53.8613683871745 30.1019871025415 -1.78929610871526 0.074524719971405 GTF2IRD2 other 1 1 1 1.62961936248213 -1.78929610871526 3.43592595522353e-08 24.0616266748926 4.87567836506571 4.93503157371792 1.29335386842282e-06 -24.8585761272221 13.5545419856494 -1.83396651495422 0.0675903764160587 SUPT3H other 0.000388500147757125 1 0.0153365901717578 4.93503157371792 -1.83396651495422 1.57244742350512e-14 106.251794946117 17.3174524680145 6.13553264502187 2.53703288855588e-09 -162.031223169134 42.7536667947553 -3.78987898153827 0.000180473151176658 NIF3L1 other 2.14387481720688e-10 1 3.33975009449496e-05 6.13553264502187 -3.78987898153827 0.175875884763337 1761.14932189807 947.364026173992 1.85899957486313 0.0639507925560665 1162.89774572774 3363.73532383368 0.34571618566064 0.729784611964324 ATP2A1 other 1 1 1 1.85899957486313 0.34571618566064 1.27028840811428e-09 716.312192993749 120.600999720649 5.93952118683064 7.4501352829859e-09 -475.230212758196 230.16044477908 -2.06477795615292 0.039749312070175 IARS essential 1.52853804148391e-05 1 9.66655052967421e-05 5.93952118683064 -2.06477795615292 1.92892803418748e-07 24.2244150611521 5.85958670971604 4.13415079616188 4.55580635564014e-05 -37.8274471870341 11.2172727870655 -3.37224991360222 0.000837030904560636 MFSD14C other 0.0020948158451276 1 0.488063534879728 4.13415079616188 -3.37224991360222 1.14293466651487e-15 495.288943870712 62.1209642719851 7.97297578482815 2.88093932081369e-14 -308.972824242084 213.664054323237 -1.44606833948148 0.149152258222496 POM121 other 1.58650761058929e-11 1 4.12291226201648e-10 7.97297578482815 -1.44606833948148 9.26242807445264e-08 181.765002387105 60.2100590788923 3.01884776676503 0.00274332764127979 -214.492604330801 110.008166435916 -1.94978801374487 0.0520827777205623 ZBTB44 other 0.00102479504215744 1 1 3.01884776676503 -1.94978801374487 0.000805956239281748 -75.6335183304721 20.9742033644221 -3.60602579351199 0.000360542906743341 -135.674051341269 46.6882063110464 -2.90595981429188 0.0039165277226101 GIMAP5 other 1 1 1 -3.60602579351199 -2.90595981429188 2.7239360621286e-10 26.0095675122073 3.83696562220337 6.77868140431014 5.9020861351937e-11 0.807806243970812 16.2110398599712 0.0498306247439113 0.9602886454817 STK31 other 3.36542300475989e-06 1 8.04867486256364e-07 6.77868140431014 0.0498306247439113 0.487649551186871 2.22507812499999 4.04021201041671 0.550733010857638 0.582200980321126 -8.47684523809527 9.2566536821739 -0.915756981858319 0.360483942763573 CGB7 other 1 1 1 0.550733010857638 -0.915756981858319 0.434557508806236 14.0899128444151 279.092425983965 0.0504847553449001 0.959767594571769 610.973933436233 503.992407672117 1.21226812970904 0.226304033578053 ADH7 other 1 1 1 0.0504847553449001 1.21226812970904 0.518119431254567 2.92579424740591 3.66875967709272 0.797488662360254 0.425758637363118 -1.50830807022733 5.25744258605773 -0.286890069751257 0.774382164270111 ZKSCAN7 other 1 1 1 0.797488662360254 -0.286890069751257 0.739798427392034 145.829158727833 187.754241019051 0.776702342042096 0.437909940011615 8.42730836875306 646.883038739568 0.0130275611881453 0.989613947714438 CD55 other 1 1 1 0.776702342042096 0.0130275611881453 1.78487098723372e-07 9.06760918591459 2.10365084266999 4.31041549385915 2.17573456981413e-05 -13.9283445390451 5.9313442372404 -2.34826103189137 0.019473495856286 ZNF565 other 0.00194158265991284 1 0.238482266197327 4.31041549385915 -2.34826103189137 0.00631736936351467 6.49231834159813 2.2147784594997 2.931362418553 0.00361780777632806 7.32387302208374 4.57936694154659 1.59931997491563 0.110736355166424 NTNG2 other 1 1 1 2.931362418553 1.59931997491563 3.61899672114084e-16 385.653671402209 46.8882103328727 8.22496036134339 4.96117676667868e-15 -250.367210751021 98.5122239369755 -2.5414836935485 0.0115098629695063 WDR5 essential 5.05573841943375e-12 1 7.15004795613731e-11 8.22496036134339 -2.5414836935485 7.33673472213711e-10 379.691593473596 106.139428295838 3.57729073511964 0.000401382208112186 -681.480450118086 194.893989999256 -3.49667247369037 0.000538331777263653 LONP1 essential 8.91780105475765e-06 1 1 3.57729073511964 -3.49667247369037 2.24629394668645e-17 532.873950252991 59.7977704858097 8.91126786038694 4.04369840016321e-17 -217.328579182967 261.46237649248 -0.831204022920742 0.40648401842424 TRRAP essential 3.18165074608669e-13 1 5.90986521183853e-13 8.91126786038694 -0.831204022920742 0.0103388924709398 35.2772459311611 11.7266646974236 3.00829322244641 0.00284757735549804 16.7467678638172 45.090346578211 0.371404727057692 0.710595672752008 SRGAP2B other 1 1 1 3.00829322244641 0.371404727057692 4.56632128476159e-08 62.605955556885 11.1144026310285 5.6328673375666 3.93989764886816e-08 45.0740113496905 26.2237018170488 1.7188271764281 0.0866314493408439 FUT4 other 0.000512660890640184 1 0.000498318254628844 5.6328673375666 1.7188271764281 2.65027755977267e-11 151.844662844663 29.5411781776787 5.1401017905033 4.79660637442806e-07 -121.754694088027 60.5420003710261 -2.01107814974505 0.0451581483827096 ASB13 other 3.37486344461452e-07 1 0.00580197507050818 5.1401017905033 -2.01107814974505 7.73858223121329e-12 17.3661634087643 2.33375543820595 7.44129531503712 9.38742236417585e-13 5.15953663006836 11.6730099932696 0.442005672319583 0.658785540991745 ZNF34 other 9.98122336181889e-08 1 1.31818184837757e-08 7.44129531503712 0.442005672319583 0.0555465638101324 27.7114832364134 13.9120664557219 1.99190273598901 0.0472447920824915 -30.7035663443 33.7987718356217 -0.908422545458899 0.36434949423568 ZNF140 other 1 1 1 1.99190273598901 -0.908422545458899 1.17688842653618e-27 12.052453081178 0.984575741597625 12.2412655237891 1.60351654848167e-28 -2.32390180386284 2.19775700168301 -1.05739706531852 0.291127984621032 INCA1 other 1.7693340604545e-23 1 2.43045003253366e-24 12.2412655237891 -1.05739706531852 0.100686771405383 2.9046805584581 4.26508699964996 0.681036649122631 0.49634081380931 -15.5801283563778 8.84052163392412 -1.7623539652447 0.0789641623760342 ZNF774 other 1 1 1 0.681036649122631 -1.7623539652447 1.24807195364795e-11 388.789003300227 61.2706728385296 6.3454338803301 7.57356732774627e-10 -603.394858823624 282.854738323274 -2.13323228170216 0.0336661350346277 PTPN1 other 1.6010267021396e-07 1 1.01144991662051e-05 6.3454338803301 -2.13323228170216 0.370628325128799 32.5240674567124 48.9783916589936 0.664049315525864 0.507142966114904 -148.758975204025 147.243494123166 -1.01029234663225 0.313128200550392 EVL other 1 1 1 0.664049315525864 -1.01029234663225 0.367508050284946 6.28622573308069 19.8309221579417 0.316991095170188 0.751458366406909 108.459273197024 78.9081297987076 1.37450061829751 0.170254146515387 THEM5 other 1 1 1 0.316991095170188 1.37450061829751 0.167543070538095 -7.70669419182054 12.073232818203 -0.638328963573123 0.523717544745361 -64.9031032751214 34.2984272024475 -1.89230552444953 0.0593555776399933 NOXO1 other 1 1 1 -0.638328963573123 -1.89230552444953 1.54717179898041e-22 1063.15275535911 104.282111193036 10.194967700559 2.59406751677822e-21 -643.777846141246 448.858177922235 -1.43425669355362 0.152478560442745 EPHB4 other 2.2817689691363e-18 1 3.87190517554317e-17 10.194967700559 -1.43425669355362 0.018634772774027 18.6749542194723 7.67876554387597 2.43202557921124 0.0155645040115426 -24.2489439916897 24.4470384999363 -0.991896993648241 0.321999547013077 ZNF765 other 1 1 1 2.43202557921124 -0.991896993648241 7.23360868697416e-05 14.6458782446009 3.4670840101044 4.22426402184581 3.12927149559517e-05 16.0235091803612 11.0160823632733 1.4545560437876 0.146772363089988 ZNF124 other 0.633374776631458 1 0.339213030122517 4.22426402184581 1.4545560437876 1.64180258342771e-10 1362.084078631 215.356882094631 6.32477618259947 8.56102374563237e-10 -774.904899648297 562.838316423806 -1.37678064381247 0.169545540976664 XRCC6 essential 2.04076061120064e-06 1 1.14152690624262e-05 6.32477618259947 -1.37678064381247 0.000427450977105535 68.4700648013454 31.4674926374234 2.17589833388619 0.030296455512292 -202.384822648713 65.8836098272686 -3.07185388261692 0.00231052639723983 PPP1R26 other 1 1 1 2.17589833388619 -3.07185388261692 3.72743412683372e-07 217.996086358609 42.6816805382973 5.10748601295129 5.63735659130278e-07 -487.239359410489 258.993716456555 -1.88127868921569 0.0608474169918516 TSC22D2 other 0.00398089964745841 1 0.00679865204911116 5.10748601295129 -1.88127868921569 0.264960645430199 -1.53480908104026 3.12940175581033 -0.490448079474165 0.624152980084301 9.71409354793033 8.25245919714937 1.17711500485647 0.240024394103195 NPIPB15 other 1 1 1 -0.490448079474165 1.17711500485647 0.351269665235713 2.14966459774814 4.65254861361938 0.462040222740594 0.644366442075943 -15.6180338898087 13.1252802301548 -1.18992003339684 0.234959892239722 ZNF569 other 1 1 1 0.462040222740594 -1.18992003339684 6.13000626942589e-07 99.1078139016721 19.9990217355498 4.95563309106767 1.17407932220111e-06 -64.1393388529586 47.5019399300961 -1.35024672565681 0.177897050616635 YRDC essential 0.00644018458665884 1 0.0139515845857158 4.95563309106767 -1.35024672565681 6.44531400810412e-19 138.462729790053 18.5644691045489 7.45848044510602 8.45613178646596e-13 -68.2903950880702 41.5568704096426 -1.64329975801605 0.101312367380387 ZNF777 other 9.26965060645534e-15 1 1.18774827072701e-08 7.45848044510602 -1.64329975801605 4.63537800797033e-19 309.630804294216 32.0958553902891 9.64706503469287 1.69444395946356e-19 -45.9043409523392 130.54950717346 -0.35162400798148 0.725351677278578 PIK3R4 other 6.67494433147727e-15 1 2.50828539319391e-15 9.64706503469287 -0.35162400798148 0.00252857569002773 0.926573183585446 10.1209490830854 0.0915500291503275 0.927113017608357 -66.7498040638886 22.5248118526987 -2.96339008291833 0.00327161377104279 ZNF775 other 1 1 1 0.0915500291503275 -2.96339008291833 0.23686956873516 24.363313967804 14.830725836555 1.64275937916356 0.101427380248049 -2.17199923961141 35.8325348518476 -0.0606152829709567 0.951703919350303 ZNF605 other 1 1 1 1.64275937916356 -0.0606152829709567 0.983424493393338 21.1888510437385 144.205077454479 0.146935540812889 0.883275426709107 55.632158393995 412.006650729077 0.135027330980094 0.892675157279131 MYL6B other 1 1 1 0.146935540812889 0.135027330980094 0.00363337107711415 8.41472155827272 4.01097192526932 2.0979258182436 0.0367235962183222 -16.502060880095 8.59491530366875 -1.91997946425965 0.0557809239646064 ZNF799 other 1 1 1 2.0979258182436 -1.91997946425965 1.05837906437306e-13 187.173953489939 33.0822441584071 5.65783725534755 3.46197498901058e-08 -223.614256857433 88.5798481420667 -2.52443712139577 0.0120825100882932 SIAH1 other 1.42193227298521e-09 1 0.00043873609035731 5.65783725534755 -2.52443712139577 0.0598414308898066 14.9625051991159 6.3421104872946 2.35923124157028 0.0189151624907681 7.23854690825907 23.893282468621 0.302953222009803 0.762122974336434 C20orf96 other 1 1 1 2.35923124157028 0.302953222009803 0.728871999400368 4.86253027676082 6.83556887774732 0.711357074111333 0.477381204123982 -8.55050766240505 22.3194682763121 -0.38309638726832 0.701902659438505 ESRRG other 1 1 1 0.711357074111333 -0.38309638726832 1.1668864028862e-24 529.612255183158 50.3599606819476 10.5165343263067 2.05554373662983e-22 -257.903465122727 137.116384053246 -1.88090917729114 0.0608921332896231 IPO4 other 1.73702709933639e-20 1 3.07817674560317e-18 10.5165343263067 -1.88090917729114 0.000771111883399171 715.640478792009 193.426984154628 3.69979649902372 0.000253921066594191 -151.267638732809 496.241145214967 -0.304826877399054 0.760696167815966 NCOR2 other 1 1 1 3.69979649902372 -0.304826877399054 0.460197028447301 -11.8608525858178 18.8810640489354 -0.628187720516025 0.530331859969437 -81.3119540729854 67.0395965418534 -1.21289444249894 0.226070409266977 SULT1A1 other 1 1 1 -0.628187720516025 -1.21289444249894 0.164101373682948 14.840105830424 7.85842066274347 1.88843362646396 0.0598864366099128 8.03274115494917 16.7045560053171 0.480871275620395 0.630941812790608 ARL9 other 1 1 1 1.88843362646396 0.480871275620395 4.74437697630029e-10 515.166363561475 83.1414549447051 6.19626351143479 1.80113290938333e-09 -344.430725678185 214.906782348045 -1.60269825789106 0.110000352286939 PRPF40A essential 5.81138735827022e-06 1 2.38055736633195e-05 6.19626351143479 -1.60269825789106 3.338599542717e-10 45.3164077518652 13.0188766875482 3.48082318002194 0.000570416098688797 -89.9897459590562 23.9552437753722 -3.7565781756549 0.000205174062039914 GDAP2 other 4.11115147690171e-06 1 1 3.48082318002194 -3.7565781756549 0.017400980269804 74.263440048324 47.6406082693945 1.55882644546402 0.120025872725717 -287.100359911406 133.605412489247 -2.14886773344241 0.0323947501413206 ANAPC7 other 1 1 1 1.55882644546402 -2.14886773344241 0.012216838394 2.29620347482478 2.88780248874334 0.795138685479834 0.427124043748288 -13.5957100167569 6.51862133163227 -2.08567261773319 0.0378026819318228 TPK1 other 1 1 1 0.795138685479834 -2.08567261773319 6.06531634244568e-06 137.861024611224 40.9706172037619 3.3648754649116 0.000858930592060941 -394.527475130771 128.488186465493 -3.07053501168939 0.00231987030412535 SLC6A9 other 0.0590155280119965 1 1 3.3648754649116 -3.07053501168939 4.31734039851833e-06 277.655530302192 87.7487639511586 3.16421015863809 0.00170487134657194 -237.46102982002 162.814097669896 -1.45847953720488 0.145692272751613 AFAP1 other 0.0425301202658041 1 1 3.16421015863809 -1.45847953720488 0.0012601473213316 1271.3442620091 353.222032100361 3.59927792286714 0.00036965091992152 -61.2416659688673 998.066263526593 -0.0613603206589455 0.9511105578399 NACA essential 1 1 1 3.59927792286714 -0.0613603206589455 0.000405424015771122 313.820992120584 97.895373138138 3.20567747035152 0.00148566815875739 -608.269863741303 309.671229727226 -1.96424402834289 0.0503807620797658 MYO18A other 1 1 1 3.20567747035152 -1.96424402834289 0.000921370653513516 59.0684169426999 15.6234694503798 3.78074902826812 0.000187233540423721 -7.45173300804849 93.1163422183303 -0.080026049461612 0.936267679494658 SPTSSB other 1 1 1 3.78074902826812 -0.080026049461612 3.99835265516493e-10 56.4692605489111 10.4401515519299 5.40885448530412 1.24656837343719e-07 -77.7109803836756 19.8854043328713 -3.90794067260762 0.000113698714682178 BORCS6 other 4.91037689580805e-06 1 0.00154611875357415 5.40885448530412 -3.90794067260762 0.224852320408706 67.2374626533008 55.2336900876788 1.21732700724082 0.224376769106419 -93.73574191905 114.252780015649 -0.820424167413795 0.412585055186027 MAN2A2 other 1 1 1 1.21732700724082 -0.820424167413795 0.215290882732429 155.55777313388 93.498926321314 1.66373860379206 0.0971560045800247 -293.829983445329 545.585643366634 -0.538558862422036 0.590570443712807 MME other 1 1 1 1.66373860379206 -0.538558862422036 0.000573515774510207 61.7575248729825 15.8667205230292 3.89226776783184 0.000120871436571937 66.1551523731162 43.3429467053695 1.52631875314838 0.127918248568936 CACNA1H other 1 1 1 3.89226776783184 1.52631875314838 0.000218597048328537 1444.6092848611 400.052186123589 3.61105209512544 0.000353896069516701 -2114.37116005844 1844.13736398582 -1.14653669588287 0.252429738004292 SULF2 other 1 1 1 3.61105209512544 -1.14653669588287 0.105802661887229 -25.5466288732111 40.9039950669666 -0.624550947441369 0.532713654149142 -202.68348054189 95.4694070291793 -2.12302020981382 0.0345243107556739 LAMA2 other 1 1 1 -0.624550947441369 -2.12302020981382 1.41270257916397e-14 2005.12018853102 299.172518151446 6.70222051450593 9.31265147736866e-11 -2708.30551037383 849.389808857709 -3.18853073362872 0.00157183598492311 PLXNB2 other 1.92848029081674e-10 1 1.2659618418335e-06 6.70222051450593 -3.18853073362872 1.44096131587763e-05 167.840102094983 40.2726456348347 4.16759563344422 3.96601758644147e-05 -93.8293617609214 89.1306392120427 -1.05271725402642 0.293264854361678 AJAP1 other 0.135695327116196 1 0.426703832125238 4.16759563344422 -1.05271725402642 6.06684994157779e-05 9.94395198278291 11.463738275844 0.867426640726476 0.386362370587999 -84.6258192994012 25.5836097225113 -3.30781387838863 0.00104801812135707 XRCC2 other 0.536188197836645 1 1 0.867426640726476 -3.30781387838863 0.12663003175539 -57.6333959837753 91.8367420692522 -0.627563594757261 0.530740225650106 -443.645085237576 218.80057159305 -2.02762306335615 0.0434323238905779 MYO6 other 1 1 1 -0.627563594757261 -2.02762306335615 1.43126534398424e-06 206.098885248216 51.6317761298445 3.99170628432217 8.14512843972908e-05 -365.942782349862 146.095285812831 -2.50482265949831 0.012749662523088 MKL1 other 0.0146504320610227 1 0.851980434795662 3.99170628432217 -2.50482265949831 6.36720943950931e-05 137.900985663082 93.906582965702 1.46849114628575 0.142956227375442 -800.657706093192 216.843644447664 -3.69232729016613 0.000261310269752719 HDAC2 other 0.560314430676819 1 1 1.46849114628575 -3.69232729016613 0.00542558797810417 5.74756297008992 2.93066772696214 1.96117864785979 0.0507250916032703 -13.0924907443717 5.61031024373672 -2.33364826107219 0.0202330564844624 ZNF782 other 1 1 1 1.96117864785979 -2.33364826107219 0.258118927246781 19.9180571574075 13.528037955749 1.47235373101115 0.141911285895975 -18.5556108922607 37.7137360099986 -0.492012005581765 0.623049261965765 POTEF other 1 1 1 1.47235373101115 -0.492012005581765 0.00757590832411499 17.8154949353938 6.07425472725456 2.93295156942587 0.00359983085311013 -0.965356010432233 13.3635746029554 -0.072237858440865 0.942457745718005 ZNF846 other 1 1 1 2.93295156942587 -0.072237858440865 0.00576427298460736 120.593726743121 299.844129484544 0.402188053341017 0.687821021845303 -11926.0181978992 3905.15563447599 -3.05391623642664 0.00245336889146678 MMP1 other 1 1 1 0.402188053341017 -3.05391623642664 0.760697250790797 -45.708423580076 67.4417453195616 -0.677746748152708 0.498422011785203 -65.0645632595567 121.788068885712 -0.534244149323152 0.593543580654065 ADH1B other 1 1 1 -0.677746748152708 -0.534244149323152 0.00253391700937461 282.327196549301 128.545090049611 2.1963281245541 0.0287877898737857 -157.545111136774 195.640490232972 -0.805278656525377 0.421258707170372 TCF4 other 1 1 1 2.1963281245541 -0.805278656525377 5.98626473680143e-08 60.4211316186384 10.2013232748466 5.92287196383816 8.27820414025814e-09 56.4730902278393 43.8375447294028 1.28823570244256 0.198609384107851 SDHAF3 other 0.000668007281979672 1 0.000107219300024623 5.92287196383816 1.28823570244256 5.08052596700046e-06 161.889744821009 32.5803088223952 4.96894445364277 1.09849059672948e-06 86.6817093543085 52.4872323759522 1.65148180672645 0.0996211727766452 HRH1 other 0.0497586713208025 1 0.013070939610484 4.96894445364277 1.65148180672645 5.33209636862827e-12 686.648512762677 109.00459991921 6.29926180428711 9.94715499062939e-10 -737.876243419717 227.804349470942 -3.23907881975642 0.00132591165868438 RABL6 other 6.90879726483165e-08 1 1.32416527235259e-05 6.29926180428711 -3.23907881975642 0.000619178223673198 24.0925903094568 8.36817278234758 2.87907419410357 0.00426316634892229 -29.0275777136998 17.8852330204825 -1.62299130687629 0.10559796739447 ZNF136 other 1 1 1 2.87907419410357 -1.62299130687629 1.78968611200178e-20 74.1458295540423 7.75319707560475 9.56325872166212 3.28291517094752e-19 -57.1699485063196 33.8975180296144 -1.68655263952875 0.0926701321898552 ZKSCAN5 other 2.6057829790746e-16 1 4.85510324631429e-15 9.56325872166212 -1.68655263952875 0.0210890260555845 18.4869556108742 7.2782429203124 2.54003003379842 0.0115568411875458 3.48316409106218 10.4299402656012 0.333958201328336 0.738629845427591 ZNF502 other 1 1 1 2.54003003379842 0.333958201328336 0.0415139512273617 18.9137772543495 7.67588737685245 2.46405090718061 0.0142801183525526 -9.83923700965827 29.157166283658 -0.337455187309234 0.736002164668981 TTC30B other 1 1 1 2.46405090718061 -0.337455187309234 2.35201657663725e-15 132.518976979071 17.2141113178503 7.69827582337372 1.79515987847251e-13 -76.8136585935325 51.014088792917 -1.50573420815854 0.133137501114042 TECPR2 other 3.25236852217399e-11 1 2.54499815971048e-09 7.69827582337372 -1.50573420815854 5.03094400527655e-07 41.6689061790533 21.0849642578236 1.97623793284791 0.048994478973257 -141.947188794017 33.7714881672918 -4.20316653180523 3.42708932233114e-05 ZFP62 other 0.00531619853037573 0.497236389777026 1 1.97623793284791 -4.20316653180523 0.0252439302244784 0.556841920942513 14.2368885590497 0.0391126135905977 0.968825147600191 -114.718149222005 43.843929812515 -2.61651156072371 0.00930746485954548 ERI2 other 1 1 1 0.0391126135905977 -2.61651156072371 0.00285166432620206 303.355632460707 90.81523220598 3.34036069822141 0.000935627767943669 -97.0508219874616 385.998726398284 -0.251427829550199 0.801644737285456 TOMM7 other 1 1 1 3.34036069822141 -0.251427829550199 0.0754222531214646 -19.7536143684134 16.5052169855195 -1.19681034098151 0.232271954346293 -88.9034651097591 40.6655828407027 -2.1862090470464 0.0295290157698107 HSH2D other 1 1 1 -1.19681034098151 -2.1862090470464 2.74714361183496e-05 27.895809808159 7.99586185397309 3.48878086160252 0.000553194938933039 -44.3705540584461 15.1536809262341 -2.92803803078839 0.00365567975349453 TRPV1 other 0.252077897821976 1 1 3.48878086160252 -2.92803803078839 0.00274314521537801 -1.21865829522945 26.703183901509 -0.0456371906707567 0.963629688505403 -178.539514092676 55.4218447707207 -3.22146465588238 0.00141506811884357 ZNF33B other 1 1 1 -0.0456371906707567 -3.22146465588238 1.74566007631111e-06 148.145056015587 28.8833735162599 5.12907731959318 5.08020850740807e-07 7.0170910072275 130.299587438792 0.0538535166930114 0.957085793900651 ZNF512B other 0.0177201954346341 1 0.00613892396035192 5.12907731959318 0.0538535166930114 7.96757272789141e-05 156.836844155738 35.5708464819149 4.40914005899403 1.42158763892035e-05 52.3047683335183 83.2299810219149 0.628436624534928 0.530169046720003 AMZ2 other 0.693577205962947 1 0.157767796167381 4.40914005899403 0.628436624534928 0.000225519281415132 40.8971917366046 23.3787468085043 1.74933207804483 0.0811983281113477 -157.681837744782 53.0934848237524 -2.96989052928467 0.00320574569816586 ZNF431 other 1 1 1 1.74933207804483 -2.96989052928467 2.64793768423599e-06 315.361536943508 73.4830492200009 4.29162290202938 2.36550815116063e-05 -415.450986968541 182.118247559922 -2.28121559774973 0.0232050208900785 NF1 ts 0.0265190959076234 1 0.258644661247904 4.29162290202938 -2.28121559774973 3.18177765368563e-14 309.02362567287 40.4756713165052 7.63479926636464 2.97325980480043e-13 -219.108496504196 151.67532714739 -1.44458891650372 0.149606676300281 VKORC1L1 other 4.31321778733624e-10 1 4.20121610418301e-09 7.63479926636464 -1.44458891650372 0.252805440379459 46.6769750900699 42.4055787137231 1.1007272275467 0.271845282853844 -84.5931462551808 81.665733384008 -1.03584628154146 0.301058441381865 DAPK1 other 1 1 1 1.1007272275467 -1.03584628154146 0.50830981251937 -2.35664604464826 3.21467518780704 -0.733089941275187 0.464040252660597 -11.6479972231519 13.0111924632229 -0.895229031164959 0.371337553104525 LCE1B other 1 1 1 -0.733089941275187 -0.895229031164959 0.322368299276406 -66.6677287063488 221.616515758336 -0.300824730856464 0.763743508223982 637.663061659165 511.755822855972 1.24602990953877 0.213664869661807 HLA-DQA1 other 1 1 1 -0.300824730856464 1.24602990953877 0.000249096933889345 426.473895122719 103.574563963278 4.11755433770325 4.87863693362111e-05 137.651718053377 207.828050372773 0.662334645426721 0.508233501484119 COL27A1 other 1 1 0.520940851772062 4.11755433770325 0.662334645426721 1.41071552588495e-05 1147.42452640324 417.878588753421 2.74583229982216 0.00637710144801277 -1697.37821768625 604.99848319822 -2.80559086481234 0.00532985774622629 GM2A other 0.13291761684888 1 1 2.74583229982216 -2.80559086481234 0.00443769668731427 8.38196599202303 2.84862942809606 2.94245573304538 0.00349401039092205 -1.83464272198062 6.47896399964879 -0.283169148968889 0.777230273424372 HIST1H2AI other 1 1 1 2.94245573304538 -0.283169148968889 0.0985055723473289 -7426.24104825218 3596.56308025977 -2.06481601532645 0.0397456853301654 8973.95734183518 12907.1998625194 0.695267558991959 0.487392202883778 S100A2 other 1 1 1 -2.06481601532645 0.695267558991959 0.00562860950898145 93.3249315676631 29.5238014153307 3.16100661479191 0.0017246207096908 -8.08810870076918 150.630310805213 -0.0536950940188146 0.957212021193124 SNHG17 other 1 1 1 3.16100661479191 -0.0536950940188146 0.0024362144975436 24.0628354464185 13.5611620971634 1.77439332072078 0.0769701113695279 -66.8478335202372 28.8793710340264 -2.31472608740251 0.0212747169464431 ZNF700 other 1 1 1 1.77439332072078 -2.31472608740251 4.78609614745528e-05 473.823089779158 124.534744749445 3.80474614319447 0.000170323437498811 -789.252777932687 503.032807304879 -1.56898867523433 0.11764818869579 CD47 other 0.427924856543976 1 1 3.80474614319447 -1.56898867523433 5.91681561314788e-10 190.564266828608 31.3210189729392 6.08422947520486 3.35067958366935e-09 -104.969007933644 59.9675270154865 -1.75043082744659 0.0810053396797039 TLE1 other 7.21733168491779e-06 1 4.39575654581582e-05 6.08422947520486 -1.75043082744659 0.110051668026126 -27.2726503864839 25.0323487765396 -1.08949626061634 0.276767878525195 -91.9914159386226 44.2380640268007 -2.07946296842673 0.0383833931424898 MAML3 other 1 1 1 -1.08949626061634 -2.07946296842673 0.0127464657718702 18.7283190856317 6.54115402100831 2.86315213270957 0.00447123415539336 4.85916039016374 14.8432980469415 0.327363930495554 0.74360669540482 HIST1H2AG other 1 1 1 2.86315213270957 0.327363930495554 1.03647134686955e-24 285.291965119901 26.9894119804204 10.5705142937856 1.55630350451115e-22 -158.901568602184 85.5633373732779 -1.85712214460454 0.0642329801962012 STRN3 other 1.54320218835407e-20 1 2.3313426497577e-18 10.5705142937856 -1.85712214460454 0.316543423095383 -2.77766306110795 6.43275636972017 -0.431799822885066 0.666191990337374 -20.2221456615845 13.4023072816413 -1.50885554528996 0.132370874918166 ZNF239 other 1 1 1 -0.431799822885066 -1.50885554528996 0.830107761979035 -255.569210618231 419.657209555283 -0.608995162716404 0.542959734137647 83.1422493887533 1532.45374005684 0.0542543289989747 0.95676639175129 SPRR2B other 1 1 1 -0.608995162716404 0.0542543289989747 0.243988372435921 12.7138969750665 10.4190440068081 1.22025561719088 0.223269281052124 28.5386897228199 17.9816644585342 1.58709944725252 0.113480804279407 CHRNG other 1 1 1 1.22025561719088 1.58709944725252 0.484871490145987 4.04793046923027 3.88026829405078 1.04320891301165 0.29763899891989 8.45786583132053 8.78038430495522 0.963268296416971 0.336140243166966 ZSCAN16 other 1 1 1 1.04320891301165 0.963268296416971 0.629948203459165 -15.7796708195774 19.1368044971147 -0.82457187781568 0.410228894977466 14.6500228932213 37.6086847970704 0.389538293409358 0.697137103871129 MVB12B other 1 1 1 -0.82457187781568 0.389538293409358 3.18047730407766e-11 856.575565407573 141.310429660785 6.0616584880803 3.8006957190171e-09 -467.069379372312 327.618074760452 -1.42565204839148 0.154946574142816 C6orf106 other 4.04047836710025e-07 1 4.9781512527686e-05 6.0616584880803 -1.42565204839148 0.0332066010878977 4.51479758022436 3.20399556927129 1.40911480138257 0.159806759139888 -11.8682663398004 6.8957778537995 -1.72109174503949 0.0862351256882617 ZNF709 other 1 1 1 1.40911480138257 -1.72109174503949 0.346519902651743 19.6873752373534 13.7908339789319 1.42756959205147 0.154390900586888 -3.83414827540641 37.6396462061273 -0.101864620469845 0.918927931328581 POTEI other 1 1 1 1.42756959205147 -0.101864620469845 0.119632976910334 0.34048811075769 37.3533414387351 0.00911533205981424 0.992732815823504 -333.219989009087 166.676004166713 -1.99920792842978 0.046433824986635 ADA other 1 1 1 0.00911533205981424 -1.99920792842978 0.961062200076533 7.13889480976216 25.3296944912293 0.281838962259655 0.778257503781961 3.25505938636075 84.1784367309676 0.0386685654042715 0.969179851038261 ARID5A other 1 1 1 0.281838962259655 0.0386685654042715 0.0037646153188613 249.970901191832 79.9137457094963 3.12800881716307 0.00192173979860041 -175.623860635488 224.113615399348 -0.783637622027312 0.433832394257928 PPTC7 other 1 1 1 3.12800881716307 -0.783637622027312 0.00654757782298916 13.7221376343045 4.29383134341502 3.19577937203998 0.0015340837092654 7.73715196046974 13.9661917803336 0.553991530559159 0.579972766380896 RGPD4 other 1 1 1 3.19577937203998 0.553991530559159 0.0093883759795084 41.5214218769992 30.7591242396225 1.34988959872639 0.178005479489199 -112.865886527542 58.4572381586399 -1.93074271181353 0.0543980936201949 NHLRC2 essential 1 1 1 1.34988959872639 -1.93074271181353 0.000503713828983406 9.58305109099491 2.65970554122121 3.60304963932015 0.0003646981369157 -0.460465545908003 5.7848311283309 -0.0795987878804098 0.936606269730042 HIST1H2AD other 1 1 1 3.60304963932015 -0.0795987878804098 0.0246725553725925 15.0468682304257 6.9862283618264 2.15378992084536 0.0320126316662353 -17.9253145131575 18.2215676182309 -0.983741623592415 0.325995160567702 ZFP28 other 1 1 1 2.15378992084536 -0.983741623592415 0.0259457712869865 -55.9525174959292 26.5362933220381 -2.10852800038434 0.0357696636699196 -173.028168352016 83.4609616885938 -2.07316288778953 0.0389646663268404 KIAA1211L other 1 1 1 -2.10852800038434 -2.07316288778953 0.344293592066012 7.76315969333525 10.2174667377457 0.7597929988513 0.447939458776176 38.4354612344364 27.8623914892927 1.37947459568239 0.16871471569548 SCN8A other 1 1 1 0.7597929988513 1.37947459568239 0.0230762413941478 9.25155162992342 3.35939562616634 2.7539333438024 0.00622499678852976 -3.4289577611745 11.3049624831487 -0.303314386605504 0.761847382799909 HIST3H2BB other 1 1 1 2.7539333438024 -0.303314386605504 0.00426270891317206 7.72190111624094 7.18304470942581 1.07501782720467 0.283179168499568 -46.6156419846883 16.7551312991652 -2.78217109447605 0.00572113817283718 KPNA5 other 1 1 1 1.07501782720467 -2.78217109447605 0.218619255591654 7.14307990563797 4.46523092231971 1.5997111974507 0.110691238379722 -6.6117322941647 14.9030248883348 -0.44365035579723 0.657607903100633 ANKRD36B other 1 1 1 1.5997111974507 -0.44365035579723 7.78879845010271e-19 996.256704113004 182.965931191802 5.44503939954066 1.03551991981513e-07 -986.964193241373 344.729377366303 -2.86301156223377 0.00447404942873214 ARHGEF12 other 1.11925033727976e-14 1 0.00128849743622596 5.44503939954066 -2.86301156223377 0.701564604886477 2.65646179618452 9.40399692811915 0.282482205863058 0.777756411511133 -17.8809747487554 24.136053077144 -0.740840877818919 0.459333194000336 HCAR1 other 1 1 1 0.282482205863058 -0.740840877818919 3.94558810608172e-08 92.8804839482352 15.7360588560746 5.90239810347307 9.20675636345079e-09 135.662238147465 78.5895373122985 1.72621245508001 0.0852835315238421 ZNF252P other 0.000444628323674349 1 0.000119080186804873 5.90239810347307 1.72621245508001 2.33594821176164e-07 754.6474940956 145.199411827783 5.19731784444599 3.61031183875619e-07 -74.6187340053122 220.636729503024 -0.338197244735218 0.735436325412471 PDLIM7 other 0.00252539361173551 1 0.00439158332066302 5.19731784444599 -0.338197244735218 0.564366380658997 -3.30294888816985 3.51482540610074 -0.939719191296634 0.348081643827843 -6.45410125668978 8.03248183772803 -0.803500261447875 0.422291542453578 TMEM26 other 1 1 1 -0.939719191296634 -0.803500261447875 0.00314374728282759 86.9969941245148 26.3235736939023 3.30490818367368 0.00105928427543367 -52.882833464521 107.46610386454 -0.492088496398635 0.622998461719523 SRGAP1 other 1 1 1 3.30490818367368 -0.492088496398635 6.87539596994064e-08 282.66842937882 62.3346821389596 4.53468951279293 8.18250119067683e-06 -242.208156019884 162.784482308736 -1.48790690970478 0.13776636952364 FAM3C other 0.000764612785817098 1 0.0924131684475041 4.53468951279293 -1.48790690970478 6.84140401105525e-23 297.551340449259 38.3686167623616 7.75507082499642 1.18940274259919e-13 -588.096156402136 104.467237867913 -5.62947933155574 3.95488387835443e-08 NOP9 essential 1.01115951283397e-18 0.000599125358731913 1.69061705833049e-09 7.75507082499642 -5.62947933155574 0.00243742212924268 76.3259411232426 26.1106422799319 2.92317363567518 0.00371332907739999 -80.6745430574633 67.0155111126885 -1.20381896247582 0.229554885778684 SLC39A10 other 1 1 1 2.92317363567518 -1.20381896247582 2.11748149244131e-14 146.186141695551 93.6016661365648 1.56178995235262 0.119341544191233 -1040.26409911778 189.765885836584 -5.48182880464404 8.64015380969632e-08 CASP4 other 2.88125706676489e-10 0.00130639125602608 1 1.56178995235262 -5.48182880464404 2.91354453129162e-08 455.685429265396 92.3975751369377 4.93178991537438 1.31345732885906e-06 -515.950510480054 214.987793346487 -2.39990607117176 0.0169722058552364 AP2A1 other 0.000330745575192225 1 0.0155697231762953 4.93178991537438 -2.39990607117176 0.0447879203110073 20.2467497935029 8.87160430547595 2.28219711974819 0.0231378687724648 -7.62356536432111 23.5819391481568 -0.323279833622885 0.746695806727724 ZNF585A other 1 1 1 2.28219711974819 -0.323279833622885 2.01741346954993e-07 69.69839645901 19.2890291941611 3.61336984652955 0.000350869993963206 -122.679567911842 45.3064791454043 -2.70777094636111 0.00713768263171189 FUT11 other 0.00218909535580863 1 1 3.61336984652955 -2.70777094636111 0.0695489763507465 191.065505626756 84.4725961342332 2.26186378033343 0.0243764347668541 186.018358937557 363.382347782016 0.511908077189111 0.60906843243448 ANXA4 other 1 1 1 2.26186378033343 0.511908077189111 2.66713284525725e-13 47.7782933789471 6.0822705597064 7.85533838225925 6.09940626946525e-14 2.64655257579478 23.9451966872885 0.110525405589995 0.91206198782458 WDR5B other 3.55635493586602e-09 1 8.70202292464608e-10 7.85533838225925 0.110525405589995 3.29001442176094e-06 117.454237566533 49.8501759962391 2.35614489255553 0.0190683718901325 -562.907141544226 151.910053196594 -3.70552922403194 0.00024847803879655 METTL9 other 0.0327060333667255 1 1 2.35614489255553 -3.70552922403194 0.0153288698751463 12.8911120099092 4.81634753352826 2.67653277097836 0.00785064916466405 -7.95755706666004 18.3340273915526 -0.434032135804841 0.664579171612129 ZNF138 other 1 1 1 2.67653277097836 -0.434032135804841 0.0497487902530109 3.3575363531954 5.14707188546279 0.652319693198439 0.514664719478341 -23.629481289703 11.6960924223859 -2.0202885234112 0.0441888893317005 ZNF429 other 1 1 1 0.652319693198439 -2.0202885234112 0.184821109993665 7.12683598166389 6.92269725345343 1.02948832235999 0.304037593356576 -20.9325614865743 18.0558649919892 -1.15932199846761 0.247200222353771 ZNF470 other 1 1 1 1.02948832235999 -1.15932199846761 1.6511970262019e-06 132.651463669629 37.957405985451 3.49474523418366 0.000541427112204569 -321.21641400941 111.335670246646 -2.8851168120496 0.00417825495051629 SERTAD1 other 0.0168009297416043 1 1 3.49474523418366 -2.8851168120496 0.000852798628059875 16.8780083072875 6.6368766639895 2.54306493276643 0.0114604422019997 -27.339870455667 15.2853143144087 -1.7886364580606 0.0746221883048957 ZNF100 other 1 1 1 2.54306493276643 -1.7886364580606 2.5879843729411e-19 106.173126813353 15.881623688821 6.68528161185986 1.03975980670475e-10 -102.25643130748 35.5512766788104 -2.87630827526449 0.00429617778225808 ZNF398 other 3.73368505484212e-15 1 1.41230574544706e-06 6.68528161185986 -2.87630827526449 2.4651243481028e-12 91.3031655637543 13.046896351669 6.9980754888173 1.53526792672703e-11 -85.2475382539464 56.1882791365202 -1.51717652798765 0.130212464230084 ZSCAN25 other 3.21772681157858e-08 1 2.11652036378589e-07 6.9980754888173 -1.51717652798765 0.551740076526735 53.3347868492069 166.281999399449 0.320749010968313 0.748609965193504 -210.98551282403 240.740636460787 -0.876401740586062 0.38146908956935 ANXA6 other 1 1 1 0.320749010968313 -0.876401740586062 0.0394586524570856 1.89407808330114 3.79680287675627 0.49886131695078 0.618225272579463 -18.0105923255973 8.09206531753464 -2.22571020114856 0.0267410675801782 ZNF441 other 1 1 1 0.49886131695078 -2.22571020114856 9.32806568296921e-09 201.857138955799 41.307118769539 4.88673974290006 1.62835421137886e-06 -337.028448906804 123.863817313303 -2.72095964921152 0.00686759959465971 GMFB other 0.000108457419695883 1 0.0191934110895226 4.88673974290006 -2.72095964921152 0.151445448857598 1.83822895949998 3.53089682306196 0.52061248221518 0.603002489597054 -6.90542658393742 5.68529057533256 -1.21461277879073 0.22542353202217 SIGLEC15 other 1 1 1 0.52061248221518 -1.21461277879073 0.081294454545217 9.82593076801868 7.29015757135988 1.34783516979398 0.178670789884599 -25.7359297758219 19.6187308158131 -1.31180401104633 0.190532493128354 ZNF420 other 1 1 1 1.34783516979398 -1.31180401104633 0.00527319178773433 1.75597544593117 1.57209217912371 1.11696722956154 0.26486500721116 -8.59348021627353 3.34787188703404 -2.56684858508331 0.0107273522775424 ZNF763 other 1 1 1 1.11696722956154 -2.56684858508331 0.00560535593987669 31.3766614481815 10.8978531142819 2.87915987847751 0.00425764924666566 -23.2090210674739 25.8681350272407 -0.897205037898302 0.370288255625704 ZMYM1 other 1 1 1 2.87915987847751 -0.897205037898302 0.180739065708535 -1.34737227882431 7.17732998604007 -0.187726115623073 0.851211841036803 20.9609225732367 14.2043452542992 1.47566974738892 0.141028275701972 DTHD1 other 1 1 1 -0.187726115623073 1.47566974738892 6.39118805114341e-07 34.9031657673658 6.55071037549733 5.32814973745744 1.875288912251e-07 14.5827920969135 14.8231385586172 0.983785723869925 0.325964105839545 ZSCAN26 other 0.00670819097848012 1 0.00230904323765465 5.32814973745744 0.983785723869925 1.38188600035963e-06 239.525486703813 49.3634766809573 4.85228154110574 1.9125941965106e-06 -109.826228712986 110.864315641858 -0.990636419637271 0.322613955455282 MAFG other 0.0141629496176858 1 0.0224366425192659 4.85228154110574 -0.990636419637271 4.51132344301231e-17 260.238494268843 36.4428086416096 7.14101091461179 6.44295661562217e-12 -377.498549843696 76.9064713821725 -4.90854076463587 1.47510012643318e-06 ARRDC1 other 6.36412398105747e-13 0.022052746890176 8.9389580085142e-08 7.14101091461179 -4.90854076463587 0.00102496704473467 446.810386844906 148.878337751741 3.0011779657963 0.00290221271934861 -683.074809732244 439.06640720224 -1.5557437292569 0.120763677662825 KIAA1671 other 1 1 1 3.0011779657963 -1.5557437292569 0.969628420212465 0.0177991841110082 0.323130278223829 0.0550836158370737 0.95610633139298 -0.223680348475632 0.94260659542666 -0.237299791409147 0.81257654945847 KRT35 other 1 1 1 0.0550836158370737 -0.237299791409147 1.72774363247819e-05 548.263251203906 247.603600325461 2.21427818692154 0.0275141047512269 -1949.44172878598 546.312757313432 -3.56836208323713 0.000414212029518882 IGF2R other 0.161457642455087 1 1 2.21427818692154 -3.56836208323713 0.476908539057209 -6.33073652748184 6.59789775667792 -0.959508128338958 0.33802723020668 -19.7129872324633 26.7045696841817 -0.738187788292282 0.46094135450052 LCE1C other 1 1 1 -0.959508128338958 -0.738187788292282 6.02642909551848e-06 58.8354260275327 14.698946533177 4.00269678474817 7.78790084111593e-05 -130.004840317295 63.6226149949089 -2.04337467624835 0.0418340737994812 GAL3ST4 other 0.0586492079575859 1 0.816327766165772 4.00269678474817 -2.04337467624835 3.30268325329799e-15 2813.17929605049 340.69163848848 8.25725958092634 4.11833139119658e-15 103.744948334038 1025.23117481934 0.101191761314047 0.919462411591372 DYNC1H1 essential 4.55208832802062e-11 1 5.94028119866194e-11 8.25725958092634 0.101191761314047 0.222138972327313 -1.88048462741011 14.8286030836576 -0.12681468488981 0.899166718724039 -44.4577673556829 27.5126833098022 -1.61590081400179 0.107101184996239 SLC6A17 other 1 1 1 -0.12681468488981 -1.61590081400179 6.12458900802173e-10 1582.10822153311 278.378814105973 5.68329248263422 2.98167742999807e-08 -1760.7428709084 755.691513560072 -2.3299757100798 0.0204309552210752 PCBP2 essential 7.46648645967929e-06 1 0.000378941384578455 5.68329248263422 -2.3299757100798 7.04288265690169e-06 102.155022605255 28.5376882295068 3.57965304630496 0.000397734587443462 -324.444412394169 128.929267557989 -2.51645276933139 0.0123461277742235 ZGPAT other 0.0681469325881807 1 1 3.57965304630496 -2.51645276933139 0.950677728327713 -10.2290509097997 36.6433027442006 -0.27915199078005 0.780311372225269 7.66468316940839 110.865900359102 0.0691347217185986 0.94492624890118 SLC25A29 other 1 1 1 -0.27915199078005 0.0691347217185986 0.000948903830249839 112.195219123507 45.0943527004574 2.48801041382658 0.0133593856444103 -244.996656232214 112.96989524998 -2.16868977075781 0.0308495076706843 PGAP1 other 1 1 1 2.48801041382658 -2.16868977075781 4.8192199004144e-19 541.545896946211 58.9607471994538 9.1848547155323 5.52411361761962e-18 -473.357135912651 308.510230614426 -1.53433205430471 0.125945400811088 SRC other 6.93678512465649e-15 1 8.11437049292146e-14 9.1848547155323 -1.53433205430471 0.0418914362589761 -2.93564840386227 3.27654894202239 -0.895957440528964 0.370953206531145 -18.9468530663949 7.48635018222123 -2.53085316679287 0.0118604135698686 ZNF682 other 1 1 1 -0.895957440528964 -2.53085316679287 0.000209448088644538 42.5372645319563 10.3452946965698 4.11174990945986 5.0002510504853e-05 17.3589606067261 25.7144459927364 0.675066482537849 0.500122520909527 ZNF772 other 1 1 0.533526787086782 4.11174990945986 0.675066482537849 8.35177562876166e-17 554.973729518338 61.7577121827611 8.98630648551215 2.40911744903092e-17 -86.1520334603104 307.851151587484 -0.279849638424458 0.779776541844506 PCNX3 other 1.17425965340389e-12 1 3.52526156316694e-13 8.98630648551215 -0.279849638424458 0.0181891832518397 2.5706655261859 60.6000295032309 0.0424202025520276 0.966190179423452 -292.671679250883 114.361637303094 -2.55917706455365 0.0109515619862386 ACSL5 other 1 1 1 0.0424202025520276 -2.55917706455365 0.408962681953583 -13.2638604469736 47.5008765561956 -0.279234014371963 0.780245623909444 -135.855933943837 102.169131863681 -1.32971604500959 0.184558910662353 LRRC8B other 1 1 1 -0.279234014371963 -1.32971604500959 4.61904128589073e-10 35.7500318869658 29.8992643556164 1.19568265833438 0.232705698870255 -341.067145859548 66.4329938523746 -5.1340023395221 4.93434861146017e-07 ABCB8 other 5.6601731917305e-06 0.0074202734419138 1 1.19568265833438 -5.1340023395221 2.53649783295627e-20 1016.56750622058 139.868153610129 7.26804122298044 2.84367409265907e-12 -995.169879612681 323.472092224636 -3.07652469419706 0.00227625307242851 SND1 other 3.68857514868502e-16 1 3.96720972666866e-08 7.26804122298044 -3.07652469419706 0.0882154312745089 20.1269271050661 10.4892474523683 1.91881516729037 0.0559140941033687 -18.4440721571141 36.1064800935444 -0.510824431219254 0.609832953169111 ZNF785 other 1 1 1 1.91881516729037 -0.510824431219254 0.538818445688235 0.156674995685746 3.80388440252764 0.0411881590254522 0.967171741066847 -14.2282367931465 13.5061707844628 -1.05346193382319 0.292929111684273 SULT1A2 other 1 1 1 0.0411881590254522 -1.05346193382319 5.22391421278311e-07 232.588717346489 46.122122480683 5.04288841962776 7.71861637935729e-07 -171.609499070461 108.574860748343 -1.58056384219751 0.114971900789423 PSMD12 essential 0.0055154086258564 1 0.00924304311428035 5.04288841962776 -1.58056384219751 0.00426394132371972 46.937449035909 34.6595223356096 1.35424396739839 0.17661406882913 -96.9070645328623 64.0925955855107 -1.51198533383738 0.131524500525108 PIWIL2 other 1 1 1 1.35424396739839 -1.51198533383738 1.64981809388476e-06 57.2977554217063 11.0129218001332 5.20277510923698 3.56390996963135e-07 -13.7173633010294 68.8237830847625 -0.19931138170849 0.842149005003196 NOL4L other 0.0167885489233713 1 0.00433549647805654 5.20277510923698 -0.19931138170849 0.0727397663391915 51.7853808719828 74.6838625478533 0.693394517976378 0.488568137960199 -328.259706208976 157.345884595523 -2.08623000882932 0.0377543268539628 CYSRT1 other 1 1 1 0.693394517976378 -2.08623000882932 0.672093178298715 4.7948032250979 7.08059655328081 0.67717503589104 0.498785685857694 -3.00119762783114 10.6333693249719 -0.282243335683166 0.777939960823789 SLC22A4 other 1 1 1 0.67717503589104 -0.282243335683166 1.09108194685105e-19 63.2437338930449 46.7942133109905 1.35152894809305 0.17748067676727 -593.677972824677 86.5321385690898 -6.86078008288986 3.55149597412494e-11 ENTPD4 other 1.5807595245978e-15 5.43591973799563e-07 1 1.35152894809305 -6.86078008288986 0.000273531452266168 42.3320456292219 10.338102711846 4.0947596294159 5.36156136097813e-05 -11.4524897860119 44.5815684197812 -0.256888444977417 0.797430497792216 C1D essential 1 1 0.570202050740025 4.0947596294159 -0.256888444977417 2.35888587143932e-14 587.498001803795 102.173233792987 5.75001866921553 2.08345053005793e-08 -619.090559743494 162.95621906398 -3.79912201755507 0.000173774251535915 TBC1D9B other 3.20784889657033e-10 1 0.000266535826310311 5.75001866921553 -3.79912201755507 0.39230740457789 2.9080502181393 3.29403840858595 0.882822194956634 0.377995054504988 -4.69018275373762 7.49200863130627 -0.626024739765931 0.531744978420772 HIST1H4J other 1 1 1 0.882822194956634 -0.626024739765931 0.561456456935889 -1.81443239843846 2.81095081640271 -0.645487067169843 0.519075600233266 -5.51618774893505 5.50949360298793 -1.00121502018688 0.317481720461521 FAM110D other 1 1 1 -0.645487067169843 -1.00121502018688 0.623251351238926 9.33891363323756 118.61786655609 0.0787310875197836 0.937295726780134 -324.454905906715 356.841823011564 -0.909240131015135 0.363907680792175 SERPINA1 other 1 1 1 0.0787310875197836 -0.909240131015135 0.991859187397233 -6.81290602140447 60.2677480698043 -0.113043978572312 0.910066572343035 3.72582217409102 164.632747444615 0.0226311121688863 0.981958631375617 TPSB2 other 1 1 1 -0.113043978572312 0.0226311121688863 0.00164660723328574 112.738782761305 49.2835366494555 2.28755463641328 0.0228218346256063 -203.695819801529 104.86319879713 -1.9424909991121 0.0529630245622634 KANK2 other 1 1 1 2.28755463641328 -1.9424909991121 1.23163143170599e-06 102.633808869027 19.5322602897607 5.25457921133841 2.73438474300394e-07 36.571649849352 44.8396124519833 0.815610301906934 0.415337386577725 C6orf141 other 0.0126771823265497 1 0.00334551973306532 5.25457921133841 0.815610301906934 1.54768407297374e-39 269.535234280146 31.1257152863672 8.65956755693257 2.39568284230503e-16 -316.133982747495 62.342750663588 -5.0709020597023 6.72727773610926e-07 GTF2E2 other 2.3630040426163e-35 0.0100983166096736 3.48595810383805e-12 8.65956755693257 -5.0709020597023 0.0793756381676241 13.0448785501209 6.12846892883142 2.1285705616865 0.0340534011632575 -17.2705302574995 31.0522261143251 -0.556176880649861 0.578478629561358 RAD54B other 1 1 1 2.1285705616865 -0.556176880649861 1.8957354830251e-06 35.2941781640599 7.89198280253359 4.4721559900928 1.07690458590519e-05 -13.5538063253256 17.8582089389501 -0.758967843396863 0.448430469752011 ZNF165 other 0.019186738823697 1 0.120527161254509 4.4721559900928 -0.758967843396863 0.617072845544284 -1.31942661544059 3.58834003476522 -0.367698323641985 0.713342030745401 -8.21129850619671 8.75833145022496 -0.937541420173794 0.3491893932232 RAMP2-AS1 other 1 1 1 -0.367698323641985 -0.937541420173794 0.000156797905542346 31.2493183128074 7.51128618407442 4.16031523057434 4.09096687428858e-05 7.77360030490168 33.516443752898 0.231933923605172 0.816738049092723 FITM2 other 1 1 0.439697119648536 4.16031523057434 0.231933923605172 0.0106730835257062 27.91453021285 19.3611338703753 1.44178178818144 0.150344925058624 -86.2240446954182 40.1270061496612 -2.14877841555957 0.0324042512166604 BLM ts 1 1 1 1.44178178818144 -2.14877841555957 2.79326426304606e-06 304.982251500907 77.6290919391743 3.92871079491531 0.000104729432642324 -289.877711737168 156.996551235139 -1.84639541096038 0.0657610002132232 DDI2 other 0.0279130897806193 1 1 3.92871079491531 -1.84639541096038 0.000222108163270525 1104.19569116316 333.333228871526 3.3125881116063 0.00103123152630239 -368.400627477961 685.944080714493 -0.537070933091554 0.591595376609013 SVIL other 1 1 1 3.3125881116063 -0.537070933091554 1.0370840055685e-06 105.312103217069 40.7989064172935 2.58124818689822 0.010290494899416 -218.067116144665 74.336062887242 -2.93353061320242 0.00359407305617054 TRIM33 other 0.0107286340376062 1 1 2.58124818689822 -2.93353061320242 9.88266445743825e-09 636.695857042108 147.28753264719 4.32280890037882 2.05979072654501e-05 -1392.2087219794 403.704923991064 -3.44857998811581 0.000638974443047567 LRP10 other 0.000114757499679773 1 0.226206217589173 4.32280890037882 -3.44857998811581 0.0532063755455036 199.531611072861 82.1603201932444 2.428564185285 0.0157110765999475 -14.421999076676 337.287289691328 -0.042758797966785 0.965920559393009 PELI1 other 1 1 1 2.428564185285 -0.042758797966785 4.53889962657877e-17 384.038508567443 42.6660602459076 9.00103047607445 2.08654190334193e-17 -16.8643195066449 186.831396259745 -0.0902649118095707 0.928133529579327 ZNF655 other 6.40257181325202e-13 1 3.05386272973125e-13 9.00103047607445 -0.0902649118095707 2.20633828677567e-72 291.351649377695 11.820523973722 24.6479470813133 1.28588485369713e-72 -14.9656371686503 154.484408822989 -0.0968747414879785 0.922893956046944 MRPL21 essential 3.38827370700139e-68 1 1.97473336982268e-68 24.6479470813133 -0.0968747414879785 0.678764196800616 -13.6470707713927 33.3905278948085 -0.408710842020397 0.683025255280173 -134.460581046278 164.832256449681 -0.815741918131941 0.415254526901618 LYPD2 other 1 1 1 -0.408710842020397 -0.815741918131941 3.76226431411465e-10 148.460149965239 22.3612975395862 6.63915632366236 1.36356052055424e-10 -33.0894505186938 47.1113574209617 -0.702366739786849 0.482964273043866 UAP1L1 other 4.62344661561549e-06 1 1.84789721745511e-06 6.63915632366236 -0.702366739786849 0.0328620063868142 5.81776195203622 2.2180146730765 2.62295918176533 0.00913423180832345 3.40393039494341 4.34027718900353 0.784265669383413 0.433464392314379 FBXL22 other 1 1 1 2.62295918176533 0.784265669383413 2.65451807504239e-13 49.2887059580897 9.99385207530162 4.93190269244626 1.31652651435234e-06 -64.0621929611932 22.3714027720126 -2.86357514609398 0.00446807805049309 ZNF786 other 3.53979985306903e-09 1 0.015604358497677 4.93190269244626 -2.86357514609398 2.99110352034392e-05 32.4773187665564 7.07407339290484 4.59103503211184 6.36031337640966e-06 -5.84165679361065 35.3831974236256 -0.165096916586462 0.868972600409767 ZNF517 other 0.273386861759434 1 0.0723803662235419 4.59103503211184 -0.165096916586462 0.00428612469074504 35.3981863796288 12.4518550231215 2.84280424996106 0.00476765499622807 -20.1703103029006 29.1094338486231 -0.692913177487122 0.488881141405147 ZNF675 other 1 1 1 2.84280424996106 -0.692913177487122 0.00108827523924829 41.7295120872047 16.0656246910735 2.59744098904481 0.00982746184313753 -36.5081452878004 24.0436641294218 -1.51841021781393 0.129901436260458 SLC22A5 other 1 1 1 2.59744098904481 -1.51841021781393 0.150224614042005 18.4137930061352 9.59515353210583 1.91907226335897 0.0558644131251769 2.47207364497865 21.9560547652066 0.112591887359295 0.910424713658702 DACT3 other 1 1 1 1.91907226335897 0.112591887359295 0.00684694276966413 41.9163445197678 29.2638608360618 1.4323586608953 0.15301730258757 -100.087265393019 48.9227496705951 -2.04582256857849 0.0415910244294081 ADARB1 other 1 1 1 1.4323586608953 -2.04582256857849 0.000139305433500429 9.50918085351375 4.32548064892152 2.19841021734422 0.0286354971724074 -13.3194759871743 6.43724392999055 -2.06912711900197 0.0393366929244289 ZNF860 other 1 1 1 2.19841021734422 -2.06912711900197 1.16534928332069e-25 602.477098082019 88.1888879469421 6.83166680188203 4.24085945349569e-11 -675.168749153511 163.10459682529 -4.13948326592365 4.45647470331318e-05 HTT other 1.74161450392277e-21 0.644005159375788 5.79852713076466e-07 6.83166680188203 -4.13948326592365 0.0982266947222729 65.1875605079694 30.4568225704897 2.14032702712499 0.0330840128366395 15.3692037578305 68.9758186679522 0.222820171686797 0.823817625797557 C5AR1 other 1 1 1 2.14032702712499 0.222820171686797 0.00423134943823451 9.17857962807076 2.75635235747439 3.32997325366666 0.000971002895642589 9.47326726359022 8.27659238057971 1.14458545594421 0.2532443942597 DIO3 other 1 1 1 3.32997325366666 1.14458545594421 0.00417622947008905 10.0135750011974 3.43238943002499 2.91737729804291 0.00378038107977728 -2.71663895560073 7.46541032893651 -0.363896803511365 0.716176134811905 HIST1H3D other 1 1 1 2.91737729804291 -0.363896803511365 0.957688037199131 3.54320165062154 12.7869521147149 0.277095090279106 0.781886561689986 0.649347026343042 21.8700098960567 0.0296912086198975 0.976331890158101 DCHS2 other 1 1 1 0.277095090279106 0.0296912086198975 0.15697331928899 4.60915600262627 2.720961672778 1.69394374376486 0.0912675873001499 -14.1814790497545 15.7688875998429 -0.899332876841344 0.369164528714027 VEPH1 other 1 1 1 1.69394374376486 -0.899332876841344 7.73041477103027e-12 118.737759183117 16.938045062124 7.01012181439007 1.41773709293352e-11 -70.6623131082043 32.100821033828 -2.20126186285828 0.0284311031748589 SHPK other 9.97146201315194e-08 1 1.95619364082968e-07 7.01012181439007 -2.20126186285828 0.549896509881436 0.897587198924845 1.44046822448501 0.623121831962482 0.533659680443548 -3.74286904236925 5.21736525258309 -0.717386815216009 0.473672196063849 GGT3P other 1 1 1 0.623121831962482 -0.717386815216009 0.111468249190491 3.8075986209552 8.45982470624415 0.450080084773487 0.652958399428667 -41.5824211542915 21.4630952069955 -1.93739163681939 0.0535799790175489 IPP other 1 1 1 0.450080084773487 -1.93739163681939 0.0969032828554266 -83.865368109443 59.0909516068943 -1.41925905453955 0.156809146361934 -261.941573861936 136.847108165014 -1.91411844484196 0.0565080526511042 MAP3K5 other 1 1 1 -1.41925905453955 -1.91411844484196 0.592237715643314 -14.5152471557179 27.6575378788071 -0.524820655378741 0.600071262203295 -59.2730285405115 58.403392018103 -1.0148901714842 0.310924910565172 OGDHL other 1 1 1 -0.524820655378741 -1.0148901714842 0.620862145770017 -4.97545616440008 8.0853240462213 -0.615368801047049 0.538749945793003 -21.198906706223 23.6065272990214 -0.898010386606159 0.369857283785198 CYP2F1 other 1 1 1 -0.615368801047049 -0.898010386606159 3.74364866419928e-08 -11.2179117444781 92.8639688045234 -0.120799400336761 0.903925738450515 -1069.22632909909 202.43858803354 -5.28173180560782 2.36934415691006e-07 GSTK1 other 0.000422395878781605 0.00357320792303606 1 -0.120799400336761 -5.28173180560782 1.48514196714064e-15 873.78868358226 152.295545219313 5.73745399002948 2.22847251123858e-08 -977.672541296276 231.419608330944 -4.22467460016675 3.12387421672266e-05 HNRNPAB other 2.0591493374405e-11 0.453805207463301 0.000284575939685167 5.73745399002948 -4.22467460016675 0.400300653333828 73.1449562023165 61.432227668558 1.19066097679139 0.23467473227559 -98.2423942733355 277.542176999936 -0.353972845984263 0.72359381422452 STMN3 other 1 1 1 1.19066097679139 -0.353972845984263 4.15582369665849e-09 172.896592802441 27.9634816502644 6.1829422732418 1.96165244483823e-09 -70.5174703416654 134.284008783831 -0.525136767812642 0.599859890538603 PDGFA other 4.910105697602e-05 1 2.59095054914233e-05 6.1829422732418 -0.525136767812642 0.134665182978446 6.3775974927084 11.0419805075794 0.577577318519146 0.563955684776722 -35.4621114615102 22.9743168687509 -1.54355455546732 0.123684595208732 COL13A1 other 1 1 1 0.577577318519146 -1.54355455546732 7.65825560519195e-06 18.7597655998152 3.93403931960912 4.76857602980927 2.82244457373255e-06 17.9166704764316 12.4997551368433 1.43336171631249 0.152730793371863 ZNF695 other 0.0738945083344971 1 0.0328024508359197 4.76857602980927 1.43336171631249 0.13396753401872 30.0016232380119 19.098340704073 1.57090208531119 0.117199822815494 51.2612826907269 30.1993170770051 1.69743185119107 0.0905934111865473 PCDHB11 other 1 1 1 1.57090208531119 1.69743185119107 0.00677572631607393 22.7699530858866 9.46601795476873 2.40544156948442 0.0167200859034914 -36.3318838000432 25.7208254003741 -1.4125473515914 0.158760662189076 ZNF628 other 1 1 1 2.40544156948442 -1.4125473515914 0.688919126669953 10.7302118635001 19.790828290169 0.54218103993304 0.588071144782115 71.6296459409863 91.6162864123913 0.781844023000023 0.434884345190124 SLC2A10 other 1 1 1 0.54218103993304 0.781844023000023 0.479983087632589 -1.69350268093931 1.73168455130168 -0.977951024432439 0.328841928316724 -5.07141307517491 5.59131448319049 -0.907016246433894 0.365084985724383 ZNF665 other 1 1 1 -0.977951024432439 -0.907016246433894 2.66359344336845e-09 140.239439347784 26.8044253300293 5.23195097903003 3.03931930212651e-07 -149.415405161202 60.8975102563336 -2.4535552362038 0.0146779987540742 RPF2 essential 3.17020891629713e-05 1 0.00370918527631519 5.23195097903003 -2.4535552362038 0.530547310548764 12.1713013469705 36.1657112645293 0.336542568123301 0.736683038484991 -69.2828877889545 69.9018647662715 -0.991145057726475 0.3223659509686 SLC28A3 other 1 1 1 0.336542568123301 -0.991145057726475 0.689662206309584 -2.75904897011698 3.67905489701677 -0.74993416715641 0.453845353541645 -4.79979425769418 12.047567645037 -0.398403594743165 0.690598397385805 FAM177B other 1 1 1 -0.74993416715641 -0.398403594743165 2.82694951462802e-11 244.573604534386 46.5061220945594 5.25895502611682 2.67034555413403e-07 -348.803530933155 104.440096721593 -3.33974729899918 0.000938595866947598 MIB2 other 3.59729325736416e-07 1 0.00326930406192629 5.25895502611682 -3.33974729899918 6.15249959692884e-10 788.875089041098 122.896675135524 6.4190108330528 5.00070959446923e-10 69.7917301369848 256.253339604413 0.27235442177934 0.785526828142369 MYO5A other 7.49928175869656e-06 1 6.70195099850766e-06 6.4190108330528 0.27235442177934 9.12997880397091e-06 -0.319520534169983 10.2752671189196 -0.031096080566281 0.975212361573198 -70.1688025421344 15.3778689716725 -4.56297310579196 7.20501004135132e-06 C5orf56 other 0.0874560669632374 0.106446818350924 1 -0.031096080566281 -4.56297310579196 0.47022523494757 -2.76738970749197 5.76743329176237 -0.479830379910009 0.631677866151535 -11.4447159469999 9.39221296565526 -1.21853241497505 0.223924932965597 GZMM other 1 1 1 -0.479830379910009 -1.21853241497505 1.41938802121617e-15 382.40873276206 75.4389013056657 5.06911853358793 6.77519725480355e-07 -468.316674219008 121.532891680119 -3.85341505287014 0.000140754493681819 ATG7 other 1.96869118542683e-11 1 0.00813633438329358 5.06911853358793 -3.85341505287014 0.00348605932157575 129.838936447193 44.0940510671571 2.94459078503453 0.00347138904427484 -125.304323878093 134.898126533782 -0.928881127542667 0.353653019859384 SIPA1L1 other 1 1 1 2.94459078503453 -0.928881127542667 0.000777372923246358 35.062221147325 9.21491403546039 3.80494283640632 0.000170875485371471 -0.755576001976775 35.0032208174095 -0.0215858993638944 0.982792168759572 TTC30A other 1 1 1 3.80494283640632 -0.0215858993638944 3.11598564900338e-08 139.183539795996 36.7936552061151 3.78281361327927 0.000185242637543769 -332.066062399491 99.325295544794 -3.34321746115253 0.000927011725712319 RAB40C other 0.000353196973314534 1 1 3.78281361327927 -3.34321746115253 2.38000571882731e-13 138.733404362827 39.0241856474636 3.55506212521936 0.000435079289522168 -220.425158466585 63.4485811299324 -3.47407545671022 0.000583469957311223 PIGN other 3.17730763463446e-09 1 1 3.55506212521936 -3.47407545671022 1.82059118574097e-10 18.4051097107281 2.90011190286557 6.3463446677841 7.53387379869296e-10 -13.7622015900735 6.20281743468288 -2.21870170047606 0.0272083590657147 ZNF624 other 2.26062807533456e-06 1 1.00622418455343e-05 6.3463446677841 -2.21870170047606 0.0155313065453738 9.8381252842751 8.41618116992192 1.16895360088433 0.243295090911234 -40.3770625066533 18.2572603427592 -2.21156196212466 0.0277055392464732 HHLA3 other 1 1 1 1.16895360088433 -2.21156196212466 0.0323817356759292 9.65843137661044 3.7559437209862 2.57150588349988 0.0105812667272336 -1.31350822320725 15.4408530437523 -0.0850670762480138 0.932261764165475 HOXA4 other 1 1 1 2.57150588349988 -0.0850670762480138 5.63346360867264e-34 170.979060823765 15.5888286852226 10.9680505364617 7.17701746791119e-24 -198.373227003859 38.6752472590155 -5.12920384646324 5.13792201003974e-07 TOPORS other 8.55723122157374e-30 0.00772486574209475 1.07863395525237e-19 10.9680505364617 -5.12920384646324 0.000138968958256659 12.7214571652461 9.70693914262327 1.31055289193955 0.190954592678726 -40.3918541174377 17.8003312252164 -2.26916306255119 0.0239279956406765 BCO2 other 1 1 1 1.31055289193955 -2.26916306255119 2.63289938447043e-13 413.536704425308 56.1156336416184 7.36936710126724 1.53746149186826e-12 -221.936164208655 244.676636900457 -0.907059076093749 0.365073335825907 ENTPD6 other 3.51176119900666e-09 1 2.15290732706312e-08 7.36936710126724 -0.907059076093749 0.166576972295229 28.7126901804601 21.4109154868716 1.34103047569665 0.180864614062903 -49.5780309666198 50.9325993627253 -0.973404687507529 0.331089738865374 ENPP1 other 1 1 1 1.34103047569665 -0.973404687507529 0.000988477617298442 12.3469277658391 3.28671434977735 3.75661723285309 0.000204598980686366 11.5794260154944 9.13469017897376 1.26763204757048 0.205851003066096 CCDC154 other 1 1 1 3.75661723285309 1.26763204757048 4.01141139295388e-08 172.53930125559 79.3922945957754 2.17324996253189 0.0305039426662008 -673.346379715748 166.430110895515 -4.04582065163962 6.56006403415678e-05 FAR1 other 0.000451765151074466 0.942418799146963 1 2.17324996253189 -4.04582065163962 0.000106456226314639 47.9928116667149 11.1257515806096 4.31366917722294 2.15528672057432e-05 -9.31931429528402 76.8584941986894 -0.121252886781679 0.903568538791241 C5orf42 other 0.914352527816431 1 0.236305636043769 4.31366917722294 -0.121252886781679 0.00313478342972811 30.064687096555 9.79520547346222 3.06932684342438 0.00233077729236153 -19.6672406392474 24.4039950518199 -0.805902500696531 0.420903194704994 ZNF841 other 1 1 1 3.06932684342438 -0.805902500696531 0.00221073464645303 197.317770515744 62.5128789626165 3.15643390274415 0.00174906717633742 -360.416142988918 330.902892512656 -1.08919006495277 0.276889646361395 MFAP5 other 1 1 1 3.15643390274415 -1.08919006495277 0.758572464097852 7.78617100421142 107.288747274137 0.0725721121928724 0.942191957870639 216.450273670506 294.195521101621 0.735736128340785 0.46243022598349 MYH6 other 1 1 1 0.0725721121928724 0.735736128340785 0.00275419829041934 20.4279744513148 6.14081025919614 3.32659267899102 0.000982451815951243 -3.22744726937653 15.2993526869444 -0.210953190988965 0.833059339865412 ZNF615 other 1 1 1 3.32659267899102 -0.210953190988965 1.50716906597158e-05 492.883865166327 103.081252696213 4.78150829830221 2.66834835845598e-06 -205.073234780403 410.993034253551 -0.498970098490499 0.618146525719125 CDC42SE1 other 0.141628677129349 1 0.0310755849825783 4.78150829830221 -0.498970098490499 0.0025846919934475 -104.839746313591 34.8404593001912 -3.00913789368487 0.00282931489709552 98.688194450723 124.286043248828 0.79404084216555 0.427763788043685 MPEG1 other 1 1 1 -3.00913789368487 0.79404084216555 0.0143708616741604 -9.53309305839936 429.151310349664 -0.0222138272177987 0.982291232699374 -1629.34543047112 696.502668077761 -2.33932403298305 0.0199334784048502 SERPINB2 other 1 1 1 -0.0222138272177987 -2.33932403298305 0.0103633816928101 107.401696468739 36.5041430497989 2.94217827062046 0.00349781839458898 -20.962869056652 99.9524890467214 -0.209728334497535 0.834013588871946 DPP4 other 1 1 1 2.94217827062046 -0.209728334497535 1.3545580675302e-05 -473.98216770076 435.025941063887 -1.08954920375921 0.276734147026145 -3095.08557815144 704.958112057137 -4.39045317050069 1.54032031672326e-05 SERPINB13 other 0.127843190413501 0.225672329603124 1 -1.08954920375921 -4.39045317050069 6.71086728055045e-13 57.7983808852956 7.56831405146128 7.63688986639448 2.72496904571094e-13 -10.9634659404024 25.4811711392491 -0.430257537241497 0.667304403214019 PDCD1LG2 other 8.87310871834381e-09 1 3.8528337337307e-09 7.63688986639448 -0.430257537241497 0.00404668793605428 14.2039080875699 4.68242201256924 3.03345321063367 0.00262082433204792 -4.01889017822295 9.96478851624366 -0.403309129107129 0.686997072285528 ZNF433 other 1 1 1 3.03345321063367 -0.403309129107129 0.916874007268578 -4.33023340442955 11.3730691843548 -0.380744488074194 0.703646276308635 -6.67993203436514 29.5929213862106 -0.225727360512565 0.821558025676458 DNAH10 other 1 1 1 -0.380744488074194 -0.225727360512565 1.4594278428065e-07 733.054191603328 167.571994137341 4.37456267902692 1.6485157965874e-05 -1038.60856018621 327.326717683403 -3.17300270364966 0.00165514743164818 SPTAN1 other 0.00159603028889318 1 0.182243421312737 4.37456267902692 -3.17300270364966 0.138883591486479 71.0980618060097 39.5289574546997 1.79863235420484 0.073019101406144 -20.0766113574263 77.4607180178878 -0.259184421099609 0.795659602083614 NMB other 1 1 1 1.79863235420484 -0.259184421099609 4.39288353837942e-11 352.665660311976 58.0794298415212 6.07212676285354 3.60710568510938e-09 -73.6323991705162 121.203762379879 -0.607509187212655 0.543947978618461 PARVA other 5.56139055958834e-07 1 4.72747271090435e-05 6.07212676285354 -0.607509187212655 4.21712899059248e-12 378.522094843696 65.7220484798429 5.75943847763342 1.9808056795521e-08 -164.165222472373 135.127656098683 -1.21488988421795 0.225303755784069 FAM114A1 other 5.47594199428433e-08 1 0.000253661975323442 5.75943847763342 -1.21488988421795 3.88758567135264e-17 162.232575433148 27.017113316421 6.00480789835318 5.22775657247926e-09 -186.618617849409 50.4190423994041 -3.70135188945228 0.000252685296773193 RPE essential 5.48771593368139e-13 1 6.81751734617021e-05 6.00480789835318 -3.70135188945228 4.0398344612138e-05 16.4406313877454 3.98180600278332 4.12893832001189 4.65839279211732e-05 -5.02810263656152 9.89724685620365 -0.508030436101518 0.611783102146018 ZNF460 other 0.364312271712261 1 0.498727532324081 4.12893832001189 -0.508030436101518 4.39259269434587e-06 216.226712009695 47.4271189565124 4.55913656083475 7.32183701683845e-06 -141.340582489183 90.51207551269 -1.56156603070457 0.119378643633275 PHF2 other 0.0432406824831407 1 0.0829637352377964 4.55913656083475 -1.56156603070457 0.00010812549311566 3857.49203194666 1252.06729877204 3.08089831571344 0.00224289581521947 -5015.61509802638 2888.37289067295 -1.73648461880482 0.0834405717129516 PSAP other 0.928149232904829 1 1 3.08089831571344 -1.73648461880482 0.879995076339991 232.976287670868 507.202742190489 0.459335623196158 0.646307006397903 458.485291165649 2153.96799121577 0.212856130191083 0.831575566578512 S100A10 other 1 1 1 0.459335623196158 0.212856130191083 0.400030016207361 -24.2524884428829 21.2116917420166 -1.14335474689381 0.253745960479258 -45.7406954520751 39.6755371222774 -1.15286896585937 0.249824618385534 CFAP43 other 1 1 1 -1.14335474689381 -1.15286896585937 1.00045020849097e-09 34.4411146122708 5.63701947020996 6.10980941156621 2.89451090742634e-09 -3.77944808238971 13.0437041822712 -0.28975266761467 0.772193114486638 LHFPL5 other 1.20904407696134e-05 1 3.80396623453969e-05 6.10980941156621 -0.28975266761467 0.0014273523088224 1186.11384018691 988.628850395877 1.19975645027146 0.23112146271795 -4374.30950157522 1734.5536453849 -2.52186463832575 0.0121584765432672 RPL37A essential 1 1 1 1.19975645027146 -2.52186463832575 0.502280061956352 -8.12896876780438 9.28681870498825 -0.875323297033681 0.382054548333548 -24.2761758137868 25.8634822213042 -0.938627505997242 0.348629940410207 HOXC6 other 1 1 1 -0.875323297033681 -0.938627505997242 5.11928295018304e-07 50.9242769861184 9.35373266331408 5.444273299134 1.03748453464364e-07 68.063835180425 37.7887394290466 1.80116712567838 0.0726178551936061 TXNRD3 other 0.00540749858027835 1 0.00129073450955015 5.444273299134 1.80116712567838 0.847052131039728 7.26934770658681 59.4076165491111 0.122363900941513 0.902688118800284 -40.7651916593918 96.7447663778245 -0.421368443851407 0.673770728303745 CFD other 1 1 1 0.122363900941513 -0.421368443851407 4.96097850633405e-05 118.558008769935 75.6413593911031 1.56737014940374 0.118016494579105 -469.347394661752 148.459597070615 -3.16144866295513 0.00172013414984919 MCMBP essential 0.443064990400694 1 1 1.56737014940374 -3.16144866295513 3.53391078468431e-05 160.963235294118 49.5769264928716 3.24673687299398 0.00129107037672338 -309.073529411765 139.819009317511 -2.21052581419668 0.0277757921355558 EME2 other 0.320419690847327 1 1 3.24673687299398 -2.21052581419668 0.970112325264384 0.066865788938194 1.22070928430196 0.0547761779139986 0.956351503786496 0.917866907956794 3.72575007254473 0.246357616610038 0.805565871569519 KLHDC1 other 1 1 1 0.0547761779139986 0.246357616610038 1.061143796066e-10 59.0850705940919 36.7998293152662 1.60558001744809 0.109355661982469 -388.46335197475 70.2442532001819 -5.53017982649354 6.66776711622755e-08 TAF13 other 1.32526248690683e-06 0.00100903319769872 1 1.60558001744809 -5.53017982649354 0.000354747580963114 20.599882844224 7.55917025612868 2.72515132563953 0.00678075954200533 -50.3499582958361 23.2540210658247 -2.16521513218344 0.0311098827408282 ZNF780A other 1 1 1 2.72515132563953 -2.16521513218344 1.56052996643331e-06 159.833020197542 62.7547219134531 2.54694810723523 0.0113422764690843 -535.910312200742 142.756408706361 -3.75401929102229 0.00020718981180618 ATAD3A other 0.0159158451276534 1 1 2.54694810723523 -3.75401929102229 1.20989885039488e-17 50.3387274579347 11.8277471653589 4.25598609390019 2.73972321256749e-05 -82.9779979315541 21.9359700434655 -3.78273665432327 0.000185197097082564 FAM118B other 1.71878230687096e-13 1 0.298191474455846 4.25598609390019 -3.78273665432327 0.0291586453087439 8.4929375418002 3.57357872746427 2.37659169966757 0.0180650407702207 -5.10634123070549 10.2794448182814 -0.496752628276593 0.619706732118208 ZNF461 other 1 1 1 2.37659169966757 -0.496752628276593 0.0966973709768731 -13.2036004353286 6.08936559038416 -2.16830476662112 0.030872046218004 -3.9898276470662 11.6571489272866 -0.342264448361551 0.732376574242448 CCDC180 other 1 1 1 -2.16830476662112 -0.342264448361551 0.0599470796928974 37.9665711187224 16.9599891743754 2.23859642411125 0.0258694129572993 -20.2877910324328 78.2954238567923 -0.259118477595071 0.795710435027333 SLC9A8 other 1 1 1 2.23859642411125 -0.259118477595071 0.450370193513392 -19.6246567962121 30.9702091083695 -0.633662392383027 0.526759545802134 -53.3303317032232 42.4972974303423 -1.25491113383474 0.210438317431598 OCLN other 1 1 1 -0.633662392383027 -1.25491113383474 3.4829552218451e-06 7.00017507002799 1.46640671221371 4.77369273593983 2.7562994043105e-06 -4.34248472116118 5.74427795439562 -0.755967025905882 0.450225092294499 HIST4H4 other 0.0345648476215908 1 0.032064030970344 4.77369273593983 -0.755967025905882 0.000117914316392849 17.1641009424425 5.8080882652417 2.95520662885936 0.00335724729048873 -41.4802979621364 18.3813182052113 -2.25665523544313 0.0247060899721007 ZNF181 other 1 1 1 2.95520662885936 -2.25665523544313 0.000147813556825523 24.3263694918787 8.38235893510942 2.90209112735413 0.00397238608958283 -37.4378177481455 17.8980922107434 -2.09172113470693 0.037276922678894 ZNF44 other 1 1 1 2.90209112735413 -2.09172113470693 2.67188975211494e-06 389.739442510067 75.5793791066692 5.15669018608907 4.42065517919504e-07 91.6184162941368 372.411736051287 0.246013772996454 0.805829785842028 GPAA1 other 0.0267509601981748 1 0.00535606581511272 5.15669018608907 0.246013772996454 0.555346626776808 4.17365679581746 8.48446495673269 0.49191750064399 0.623114940158115 18.0303305410254 17.7940292644236 1.01327980712464 0.311692058111933 ADAMTSL2 other 1 1 1 0.49191750064399 1.01327980712464 0.00427629324749932 26.4457214775063 11.906279512978 2.22115745297933 0.0270465407471389 -23.1315223932454 16.7262823565805 -1.38294463169486 0.16765516856664 SGTB other 1 1 1 2.22115745297933 -1.38294463169486 0.121812557672064 7.13162146712549 4.72599206322761 1.50902104187093 0.132286298304241 -11.0760186195569 12.6029799208511 -0.878841249380401 0.380150930831913 ZNF790 other 1 1 1 1.50902104187093 -0.878841249380401 0.654959397210734 -255.002093518281 323.613949008615 -0.787982391672158 0.431290308879935 -919.328551591561 1473.45043418974 -0.623929064907504 0.533118686915787 PRB3 other 1 1 1 -0.787982391672158 -0.623929064907504 0.384857721681628 -10.8064333349264 15.8208366985486 -0.683050684412773 0.495073707006489 -66.5696015573017 50.5271721511102 -1.31750103406171 0.188622159923998 FAM49A other 1 1 1 -0.683050684412773 -1.31750103406171 3.08033923357804e-16 1408.22544719968 162.146123134452 8.6849159263091 2.02247181544253e-16 -555.411021252293 309.450435158929 -1.79483031254114 0.0736303043046038 MYO1C other 4.3063142485421e-12 1 2.94431446892124e-12 8.6849159263091 -1.79483031254114 3.40105392384621e-17 32.2966177689126 6.93395649689182 4.65774738901083 4.69401537638526e-06 -51.440963051803 10.6525394662981 -4.82898591594511 2.13045326065684e-06 NKIRAS1 other 4.80364856204039e-13 0.0317757103826968 0.0538121922748806 4.65774738901083 -4.82898591594511 3.60031235007695e-07 19.5286937342635 65.9001750584548 0.296337509224234 0.767164573339837 -535.014573889505 125.838912847875 -4.25158293076067 2.78889227617825e-05 KIF13B other 0.00385125412087732 0.40570015941565 1 0.296337509224234 -4.25158293076067 0.570170575758116 484.595381515 839.260718812617 0.577407438061207 0.564070272387238 -918.287498147341 1626.18686400919 -0.564687563570278 0.572681911615935 NRAP other 1 1 1 0.577407438061207 -0.564687563570278 0.0148130654929018 36.6381999910085 122.324802669477 0.299515708927857 0.764741033360071 -567.475724154467 220.897330330807 -2.56895691452965 0.0106534548861409 ADH5 other 1 1 1 0.299515708927857 -2.56895691452965 0.00613348417596816 225.905772517471 74.0522201033688 3.0506279514933 0.00247459138137563 32.870917741706 168.040558363519 0.195612999991329 0.845037235767218 HIST1H2BK other 1 1 1 3.0506279514933 0.195612999991329 4.41265507219333e-19 194.34259065111 19.8149169857061 9.80789325493025 5.52304126222401e-20 58.6216505971147 96.9986726307573 0.604355183501 0.546043944219472 TEAD4 other 6.35598836598727e-15 1 8.2028208826551e-16 9.80789325493025 0.604355183501 1.81527940671814e-05 93.6332697330529 34.348037686544 2.72601511001993 0.00676344869875177 -200.633446866361 88.0091438574644 -2.27968865588896 0.0232839844187569 SPG7 other 0.1692566518824 1 1 2.72601511001993 -2.27968865588896 0.411078776404211 -45.2705019320164 38.3839491334166 -1.17941230524934 0.239115651680014 -109.367141988506 171.860362545064 -0.636372112620377 0.524991686365662 HRNR other 1 1 1 -1.17941230524934 -0.636372112620377 0.0280188919819593 0.980239991408713 2.81326094992682 0.348435502022737 0.72774370573312 -15.3155989570927 6.23801994963934 -2.45520198408121 0.0146155615484176 HES5 other 1 1 1 0.348435502022737 -2.45520198408121 0.89886496144025 -2.11683424490141 5.9229157904407 -0.357397322500832 0.721030712066494 -6.53615211530179 18.5845811786559 -0.351697574051788 0.725297277908033 ZNF677 other 1 1 1 -0.357397322500832 -0.351697574051788 1.68045847012289e-06 1027.81212770491 227.597021724449 4.5159296018789 8.91212136588897e-06 -1149.45986225258 694.152625325533 -1.65591805075076 0.098731062566606 ERO1A other 0.0170885821826796 1 0.1004574320363 4.5159296018789 -1.65591805075076 3.74209307299488e-07 15.7056178427963 5.59521270317343 2.80697422528522 0.00531151720873768 -44.1163419069891 11.9266168566475 -3.69898206987342 0.000255214165546286 ZNF823 other 0.00399505856472934 1 1 2.80697422528522 -3.69898206987342 0.0547869390545861 6.66646330193317 3.47507583035632 1.91836484363842 0.0559543492494011 -4.89546243417404 7.87059001906524 -0.621994338711021 0.534388492792261 ZNF311 other 1 1 1 1.91836484363842 -0.621994338711021 0.442118386608733 -7.67696149092665 7.63939445848929 -1.00491754060371 0.315700600891611 -24.0796064945961 24.3869304821261 -0.98739800452725 0.324198242131143 ZNF347 other 1 1 1 -1.00491754060371 -0.98739800452725 0.829548770552683 10.8838872688967 30.4664369269285 0.357241882107871 0.721146214706342 47.115520882633 77.7864752845544 0.60570324995801 0.545141183618621 PLCG2 other 1 1 1 0.357241882107871 0.60570324995801 0.0128942641439203 75.6368854186945 38.3916531479651 1.97013879884731 0.0496871047501993 -78.3897131752316 54.7408459254986 -1.4320150127369 0.153118612897183 FCHSD1 other 1 1 1 1.97013879884731 -1.4320150127369 0.013102727819679 31.980065644775 11.7588647670816 2.71965587480023 0.0068964041368538 -9.80842642788947 30.1927192339364 -0.32486065106931 0.745501499355536 ZNF71 other 1 1 1 2.71965587480023 -0.32486065106931 0.0526214138016567 15.1365812181578 6.24626826557007 2.42329989276827 0.0159398621092996 -5.2044234549014 37.8281870830336 -0.137580567725268 0.890659258984472 AADACL2 other 1 1 1 2.42329989276827 -0.137580567725268 0.879783102260977 91.0440283995853 1387.31156657301 0.0656262303243716 0.947716384964432 -2507.35858544747 4978.7275411973 -0.503614340150152 0.614878919654469 S100A6 other 1 1 1 0.0656262303243716 -0.503614340150152 1.06748055174987e-07 1388.00616455789 304.537250745347 4.5577549582548 7.36718732712175e-06 -1795.72031068448 596.550688452146 -3.01017222081126 0.00281863411061696 RPL12 essential 0.00117604332386283 1 0.0834554980416352 4.5577549582548 -3.01017222081126 0.333125401560427 7.56261017622728 7.08784352768307 1.06698322934048 0.28678371720765 -24.3158245420223 22.8538830919492 -1.06396906137094 0.288144915454101 DNM3 other 1 1 1 1.06698322934048 -1.06396906137094 4.52557581402509e-07 148.097213654957 33.0360670937292 4.48289480811318 1.02714115460311e-05 -109.610192384694 72.6805125926669 -1.50810978726852 0.13251305232228 ZNF121 other 0.0047984680356108 1 0.115152794842555 4.48289480811318 -1.50810978726852 0.0965487938347304 286.920076553734 143.935657366319 1.99339122635552 0.0470726646852852 -441.218736662292 474.514585945367 -0.92983176857095 0.353163493467021 MPZL1 other 1 1 1 1.99339122635552 -0.92983176857095 2.55763417968168e-06 107.928021568179 32.2579830131482 3.34577712202862 0.000918152635339216 -201.445323888317 62.0963704813459 -3.24407565734992 0.00130280165543109 VPS13A other 0.0256428402854886 1 1 3.34577712202862 -3.24407565734992 4.86253889613476e-17 275.429413587754 63.2573972713819 4.35410600923285 1.81059600318986e-05 -333.13327157182 95.8898199048008 -3.47412553180884 0.000584540037114284 MBP other 6.85666609743963e-13 1 0.19960010339165 4.35410600923285 -3.47412553180884 0.999716470652279 -0.168132470456149 9.57207777045791 -0.0175648876333885 0.985996983199705 0.150071122710191 21.6285336355568 0.00693857129840174 0.99446821623778 ELOVL2 other 1 1 1 -0.0175648876333885 0.00693857129840174 0.0426210611240088 5.61930773976923 12.1537568262498 0.462351503333734 0.644147453199833 -51.7668489970922 23.9303551590635 -2.16322944866473 0.0312729656760815 GOLGA6L9 other 1 1 1 0.462351503333734 -2.16322944866473 0.00701490728472831 59.6187722449779 49.2589560333581 1.21031335306018 0.227057521352541 -310.748011122769 117.000521398328 -2.65595407104921 0.00830706988576359 C1orf122 other 1 1 1 1.21031335306018 -2.65595407104921 0.00682330420793206 -12.995207534136 26.6649569748463 -0.487351528314659 0.626343969299049 -169.446620519163 53.4308150368333 -3.1713276393473 0.0016648991182972 SNHG12 other 1 1 1 -0.487351528314659 -3.1713276393473 0.713777802649923 -3.98219125045188 5.01310458340582 -0.794356308390928 0.427586071967397 -0.916138724981487 9.37783632838681 -0.0976919081225939 0.922239071964842 PCDH20 other 1 1 1 -0.794356308390928 -0.0976919081225939 0.0259920421147033 -49.8958164902924 23.3650539812652 -2.13548903119592 0.0334800220159092 -128.158093882033 50.9345938816302 -2.51613067103012 0.0123540921138629 KEL other 1 1 1 -2.13548903119592 -2.51613067103012 2.33585058223329e-09 141.476498289966 26.7012558876573 5.29849602899628 2.17785347373749e-07 -153.685903284293 50.9578937612324 -3.01593908108528 0.00276704663955266 NOL8 essential 2.78666974460432e-05 1 0.00267527520713913 5.29849602899628 -3.01593908108528 0.0340746426837984 29.7789687924017 18.9339903891605 1.57277827760226 0.116774009894938 -91.2286558410294 52.2898847600421 -1.74467119710967 0.0820174020809298 IRAK4 other 1 1 1 1.57277827760226 -1.74467119710967 0.258431230037306 12.5417157862249 9.5198599868446 1.31742649614135 0.188644111479571 -10.6205920993826 20.0856894342903 -0.52876413001045 0.597337939157383 CCDC151 other 1 1 1 1.31742649614135 -0.52876413001045 0.26309474062891 25.0654597907389 41.9030672461585 0.598177208448548 0.550146149839923 -142.711380769083 101.939928771288 -1.39995566496098 0.16249837363012 MRPL42 other 1 1 1 0.598177208448548 -1.39995566496098 0.00056826205448618 107.526205279042 45.3638145824674 2.37030783827866 0.018365716630424 -138.686170917176 82.9676869441962 -1.67156848678277 0.0955869811874538 ENTPD7 other 1 1 1 2.37030783827866 -1.67156848678277 1.22811339389257e-05 55.9787386580039 13.1413957430932 4.25972550803251 2.69448205731031e-05 -72.4063806429929 59.7437796841773 -1.21194844092144 0.22642622184079 ZNF335 essential 0.116290057267687 1 0.293509930502812 4.25972550803251 -1.21194844092144 0.000384189258265304 30.5408447579 8.54376793333265 3.57463416565283 0.000408974145838486 -28.5395035825536 32.5229178804795 -0.877519775053247 0.380911287453596 ZNF273 other 1 1 1 3.57463416565283 -0.877519775053247 0.439500307475512 27.3333333333334 23.6416437435952 1.15615198459872 0.248495103256843 -17.1219512195122 57.4363647019656 -0.298102975499182 0.765821100233088 ZNF84 other 1 1 1 1.15615198459872 -0.298102975499182 2.59098766723105e-33 135.256227956783 18.5525504994628 7.29043847425182 2.54145245448132e-12 -232.643328631598 41.1887416631038 -5.64822617147336 3.64220057086988e-08 MAK16 essential 3.93260108132329e-29 0.000551829808492495 3.54888420743772e-08 7.29043847425182 -5.64822617147336 0.218983159292981 0.190845058084318 8.61463195005236 0.0221535939307491 0.982339417232902 -37.4109400360917 22.466006064319 -1.66522433622541 0.0968590722697698 ZNF667 other 1 1 1 0.0221535939307491 -1.66522433622541 2.77302824116737e-10 575.291479754976 99.4592167864026 5.78419475180932 1.73399458856327e-08 -729.29702884514 367.059882974976 -1.98686117081026 0.0477902451932665 SIRPA other 3.42413527219346e-06 1 0.000222454165766782 5.78419475180932 -1.98686117081026 4.06368084811194e-14 217.592731441227 49.2681979688963 4.41649462354187 1.37417874662781e-05 -377.555006923424 74.8651384432456 -5.04313509297314 7.68557433200979e-07 GRK6 other 5.4961283470714e-10 0.0115268243831483 0.152739967687681 4.41649462354187 -5.04313509297314 0.462449047177782 -15.9673395762972 16.9982794531143 -0.939350339564616 0.348259391013373 -47.6313581005014 48.0304389827254 -0.991691084015127 0.322097508701067 PRIM1 essential 1 1 1 -0.939350339564616 -0.991691084015127 0.00031893328502832 43.0328687014468 39.8620079561299 1.07954593629118 0.281159974050542 -229.064159430175 76.584558554571 -2.99099666765009 0.00299726954023126 MARCH5 other 1 1 1 1.07954593629118 -2.99099666765009 0.108832655141982 14.9168902693457 26.4866019290656 0.563186259577387 0.573709983175279 -163.519889354671 91.1731723024152 -1.79350882749024 0.0738537496547742 NPIPB13 other 1 1 1 0.563186259577387 -1.79350882749024 0.00468634953361009 2533.05376084974 891.834761085646 2.84027251613988 0.00479896956596942 -231.905741279407 1961.72067879112 -0.118215474703726 0.905971799978585 AKR1B10 other 1 1 1 2.84027251613988 -0.118215474703726 1.22156200607645e-11 44.437087303465 6.02002912854718 7.38154024749529 1.47848232427525e-12 24.0572881939216 28.379115846509 0.847710983105942 0.397259353327105 ZBTB14 other 1.56775267859851e-07 1 2.07105803984477e-08 7.38154024749529 0.847710983105942 7.25491814768318e-10 289.52712694659 48.1153921049134 6.0173494235543 4.90608998906638e-09 -108.986399293107 116.354883845435 -0.936672322563474 0.349642429838618 CD2AP other 8.81980399213845e-06 1 6.40342865372944e-05 6.0173494235543 -0.936672322563474 0.0266009193132441 -22.0669661145989 20.146618368529 -1.09531861431741 0.274208555515978 -152.579169218201 57.3453739871521 -2.66070580082686 0.00819457808697655 SFI1 other 1 1 1 -1.09531861431741 -2.66070580082686 0.0938414359319117 -14.4082766850935 12.4837224186963 -1.15416509610266 0.24930186408237 -57.5102831226695 26.7323133180475 -2.15133955817596 0.0322046868612906 TMPRSS11F other 1 1 1 -1.15416509610266 -2.15133955817596 0.00372942666815178 31.23507609747 10.2647753693753 3.04293810370748 0.00253747840978699 -18.0478841365494 25.3548123635131 -0.71181296385854 0.477100827647062 ZNF649 other 1 1 1 3.04293810370748 -0.71181296385854 0.000993480008825287 6.15905676954912 6.58526424541909 0.935278606903822 0.350417555155868 -36.5873799116777 13.4297516531893 -2.72435268026635 0.00683119951523283 ZNF248 other 1 1 1 0.935278606903822 -2.72435268026635 0.355285272293464 5.1187857494805 9.2919850832517 0.550881830267553 0.582099072917673 19.9457068489043 13.8419455911906 1.44096122308112 0.150573404893956 CHSY3 other 1 1 1 0.550881830267553 1.44096122308112 1.05727585860612e-05 113.903192968517 47.5473551756961 2.39557368748742 0.0171722500953151 -391.380925703554 100.173992145944 -3.90701136412082 0.00011418615838283 TOR4A other 0.100673807256475 1 1 2.39557368748742 -3.90701136412082 0.619799641034632 13.2855933928381 31.4153382603913 0.422901491071596 0.672651183762807 57.5699413283834 62.7323503710817 0.917707386824166 0.3594632262358 LPAR1 other 1 1 1 0.422901491071596 0.917707386824166 0.214969236451695 1184.50824320968 1221.68673202404 0.969567903260462 0.332994168581487 5254.56287114267 3206.17139676318 1.63889019671483 0.102218884111043 MB other 1 1 1 0.969567903260462 1.63889019671483 0.00367208283834994 22.7876000621553 26.9479559686952 0.845615158664618 0.398417582445977 -207.056285432153 68.2009776780952 -3.03597239337898 0.00260032071754769 HIBCH other 1 1 1 0.845615158664618 -3.03597239337898 3.56928080909103e-07 78.5503350177699 21.9825245461788 3.57330819091132 0.000407478567167231 -170.937148848984 55.8636016719946 -3.05990204234679 0.00240379148343001 ZNF544 other 0.00381948739380831 1 1 3.57330819091132 -3.05990204234679 0.158076814617889 -0.363706297009389 22.6089333569673 -0.0160868401559203 0.987175264093424 -133.936289040305 71.5813688699066 -1.87110544482216 0.0622544075804595 TMEM229B other 1 1 1 -0.0160868401559203 -1.87110544482216 0.117798648646578 237.962013302341 119.742295548268 1.9872845448033 0.04774576710641 -111.954656082597 389.475908598315 -0.287449502295303 0.773954802751319 SOWAHC other 1 1 1 1.9872845448033 -0.287449502295303 2.10138892766505e-07 488.459956966221 95.6232601250637 5.10817092334411 5.61851212596646e-07 -65.9208679508163 199.77785193353 -0.329970851687551 0.741639248651201 ZNF770 other 0.00227853601426722 1 0.00677648747512814 5.10817092334411 -0.329970851687551 0.204686111181498 1.81842583415922 1.36234484929715 1.33477645920368 0.182910405059613 -3.78411718773464 4.89723593343701 -0.772704692844734 0.440274728412442 NPIPB6 other 1 1 1 1.33477645920368 -0.772704692844734 1.04784880337998e-05 130.211372930756 34.6193151304461 3.76123480317613 0.000201015900025277 -154.356203687674 78.2279682399696 -1.97315879678961 0.0493377151841677 MIER1 other 0.099828555498011 1 1 3.76123480317613 -1.97315879678961 0.0122531894082082 108.951777636185 63.0734659018551 1.72737895529189 0.0850798307750551 -167.970470737307 116.166809857075 -1.44594201169825 0.14918766757864 MAN1A2 other 1 1 1 1.72737895529189 -1.44594201169825 0.0266488370567936 -64.7177223932868 25.621834856256 -2.52588164572784 0.0120246067537673 -107.792805610814 53.8231110052899 -2.00272343232295 0.0460528798060519 SVIP other 1 1 1 -2.52588164572784 -2.00272343232295 0.00200393604425496 35.0592828574891 9.87449751109565 3.55048779121106 0.000442605697091458 31.8326968407045 49.3903972278023 0.644511861159634 0.519708207117046 ZNF251 other 1 1 1 3.55048779121106 0.644511861159634 1.73770040020449e-07 192.789389028412 45.9557228919199 4.195111661758 3.53610064399849e-05 -428.576637186027 168.164576800693 -2.54855478686199 0.0112837650534587 DDRGK1 other 0.00189131311558257 1 0.381863508545397 4.195111661758 -2.54855478686199 2.80376970110236e-13 557.622069783656 81.7739263854574 6.81906928566931 4.70876152774064e-11 -487.700065480943 200.515729388233 -2.43222846890316 0.0155647601615456 TFDP1 other 3.7360231267189e-09 1 6.43310999919926e-07 6.81906928566931 -2.43222846890316 0.238587836136564 12.5688948204721 7.41355640064062 1.6953934307947 0.0909735165643143 11.5228187076697 21.6729949380405 0.531667115717579 0.595325453007133 ZNF607 other 1 1 1 1.6953934307947 0.531667115717579 9.04546153035467e-06 -284.229146537192 550.236558237777 -0.516558091755085 0.605827127501476 17473.3809392901 3653.16829021689 4.78307582655951 2.65589747869545e-06 BPIFA1 other 0.0867007487684495 0.0395516252527327 1 -0.516558091755085 4.78307582655951 0.00802857969488716 10.2985355289198 3.58831014333074 2.87002380439738 0.00437762479715783 30.9959215861992 16.3132756088198 1.90004278291242 0.0583262197979861 ZNF334 other 1 1 1 2.87002380439738 1.90004278291242 0.409847407921722 39.9525012950666 30.0043631652683 1.3315563831501 0.183956704580741 23.6067117156369 55.3442201239981 0.426543398077457 0.669999633193125 HSD17B11 other 1 1 1 1.3315563831501 0.426543398077457 2.12075315112563e-15 233.233354766047 30.4315498450465 7.66419574269601 2.16818029428425e-13 -259.025406638784 95.9793416566811 -2.69876206866807 0.0073292797325409 SZT2 other 2.93448613521253e-11 1 3.06905920655935e-09 7.66419574269601 -2.69876206866807 0.105608713916065 -6.61005437883879 5.0385401267901 -1.31189872711202 0.19049465689167 21.8868922509087 16.4447749551984 1.3309329139825 0.184158591329189 RPS6KL1 other 1 1 1 -1.31189872711202 1.3309329139825 1.9870470505902e-22 209.822395988213 50.725876353255 4.13639765485785 4.52046312517291e-05 -450.674632568283 71.9063843886668 -6.26751903047031 1.19290593592051e-09 QRICH1 other 2.92791382904466e-18 1.81977800524673e-05 0.484412828493529 4.13639765485785 -6.26751903047031 1.63606566838685e-06 298.025827188505 64.5441395779572 4.61739561697225 5.6420289604134e-06 -294.598657591227 148.838532084439 -1.97931713962413 0.0486397662840888 DDX42 essential 0.0166551485041782 1 0.0643868344962377 4.61739561697225 -1.97931713962413 3.79095845033605e-15 978.776533339 114.48578345917 8.5493281677901 5.56248597159442e-16 61.1335210184833 363.795529284251 0.168043629174774 0.866657484045103 RPL23A essential 5.22052888195777e-11 1 8.07283589057498e-12 8.5493281677901 0.168043629174774 0.0175385069816049 20.7692884919305 10.6176652245964 1.9561069267674 0.0513222445088849 -30.4839464234592 24.4937124602188 -1.24456210845822 0.214203496284082 SLC29A3 other 1 1 1 1.9561069267674 -1.24456210845822 1.28242323565576e-20 145.335348594355 14.7437943752134 9.85739117731366 3.66638155836027e-20 -39.8986946604743 45.453637850627 -0.877788809590823 0.38072523011499 STYX other 1.86951659293897e-16 1 5.45007618650254e-16 9.85739117731366 -0.877788809590823 5.57761533275123e-06 428.302690967186 117.467187046924 3.64614750497171 0.00031059657507697 -505.084546513895 254.678656301464 -1.98322291254758 0.0481970793747899 UBL5 essential 0.0544542584936503 1 1 3.64614750497171 -1.98322291254758 0.0101243610664914 108.405710893972 41.2053765356665 2.63086325155015 0.00893159514442023 -118.405406366448 97.000480004293 -1.22066825196337 0.22311599305628 HELZ other 1 1 1 2.63086325155015 -1.22066825196337 0.4273046573043 -18.3197959617428 41.4874582531899 -0.441574315060245 0.659095507071022 -142.262805526036 111.076191298974 -1.28076776726274 0.201202726802363 TMEM116 other 1 1 1 -0.441574315060245 -1.28076776726274 0.4376085836857 31.192841247815 32.0199259018504 0.974169688694138 0.330712734180324 -94.435691326641 145.881301135252 -0.647346099820473 0.517875004194729 CARD11 og 1 1 1 0.974169688694138 -0.647346099820473 2.12989610388326e-05 11.7734420966678 3.33288941448198 3.53250307241222 0.000475315489195069 -10.2552109083994 6.94389861846427 -1.47686645094878 0.140743191899091 ZNF485 other 0.197313575063745 1 1 3.53250307241222 -1.47686645094878 0.154849406965033 24.7582289021479 15.6745931086234 1.57951333923476 0.115212504268793 -23.4118193048016 40.0111798752154 -0.585131940068177 0.558873962980083 PEG3 other 1 1 1 1.57951333923476 -0.585131940068177 1.71935163940067e-13 199.839784613707 29.1564403982348 6.85405289137439 3.75307019126695e-11 -89.5582440000279 59.784211332851 -1.49802501368478 0.135121838420508 SDAD1 essential 2.30066442868203e-09 1 5.14020493395921e-07 6.85405289137439 -1.49802501368478 0.00153078795128369 80.1318856293973 22.4765089290127 3.565139314227 0.000419136738144646 37.4057786819085 50.8605001703282 0.7354583332181 0.46259909837576 ZKSCAN8 other 1 1 1 3.565139314227 0.7354583332181 5.40812492233252e-06 67.0713298329576 13.3637173399281 5.01891263687252 8.64013234704055e-07 24.1243611040123 37.4777953609343 0.643697444625005 0.520232700109094 FAM109A other 0.0528481967410334 1 0.010331777040972 5.01891263687252 0.643697444625005 1.33848852551484e-06 11.5952615831238 9.92435679145454 1.1683640387766 0.243532371857016 -60.2819122363338 18.3774859462733 -3.28020450743744 0.0011520335114711 HYLS1 other 0.0137342307603078 1 1 1.1683640387766 -3.28020450743744 0.59049699360727 6.64064066228015 7.11488742225312 0.933344446394235 0.351348060816987 8.61537877331173 17.1068038340673 0.503622936048091 0.614873970522206 MYL4 other 1 1 1 0.933344446394235 0.503622936048091 0.0155158671275065 1.39831649250577 1.57216339216955 0.889421862555979 0.374468295624599 -8.02880773843934 3.36891193730271 -2.38320498958116 0.0177666534142835 ZNF442 other 1 1 1 0.889421862555979 -2.38320498958116 0.957395098769068 -0.263970119634363 8.1381182549164 -0.0324362600008784 0.974144431503731 7.31360421671088 25.9094888570529 0.282275125420702 0.77791560883684 ZNF813 other 1 1 1 -0.0324362600008784 0.282275125420702 0.987712180563258 -1.03387372455585 6.61886771401669 -0.156200995279967 0.875973086649751 -0.887660303064386 18.4333271580595 -0.0481551862804257 0.961622605238161 HOXC4 other 1 1 1 -0.156200995279967 -0.0481551862804257 0.0077228034623197 199.752675569915 90.2010590126132 2.21452694410143 0.0275012770470797 -408.35974639074 254.797549873612 -1.60268317569498 0.109997404130364 PIM3 other 1 1 1 2.21452694410143 -1.60268317569498 1.17096450316853e-23 328.712670238559 34.7987495608172 9.44610580515467 8.23933101168561e-19 -462.310998034461 115.416530615477 -4.005587376168 7.72368290191089e-05 ASNA1 essential 1.73583777949702e-19 1 1.2161252573248e-14 9.44610580515467 -4.005587376168 0.000174907665060311 572.670571557447 136.123372342874 4.20699665091294 3.38640808196253e-05 587.626981672242 633.766576614099 0.927197809659894 0.354540526532403 ASPH other 1 1 0.366307762225887 4.20699665091294 0.927197809659894 4.56166386575388e-07 202.91482931158 37.0919588623959 5.47058811491612 9.07883905862603e-08 116.075375854248 158.893459716761 0.730523308266814 0.465606541658124 SPRED2 other 0.00483490753131253 1 0.00113276674934477 5.47058811491612 0.730523308266814 8.30089380567265e-12 153.909185784285 34.3213761117711 4.48435357845396 1.02055390717787e-05 -344.328839967498 93.619589965778 -3.67795714650496 0.000275703234787957 WWP2 other 1.06990220261315e-07 1 0.114424504072783 4.48435357845396 -3.67795714650496 0.00137327436803451 272.1269296741 74.714988054067 3.64220000245704 0.000315353522156905 -139.045025728988 321.206940823996 -0.43288300486999 0.665392291821 GFPT1 other 1 1 1 3.64220000245704 -0.43288300486999 1.15726117191969e-14 129.840114907245 19.4293602162935 6.68267577840059 1.06071680355863e-10 -80.8256746552225 60.1671481677216 -1.34335226309735 0.180121851754669 UVRAG other 1.58278610483456e-10 1 1.44045341923262e-06 6.68267577840059 -1.34335226309735 0.000812508903114238 41.9971821379857 11.9262669669362 3.52140214992811 0.000492673535297028 -19.7342288154736 28.9743567103504 -0.681092906142899 0.496313079836382 ZNF26 other 1 1 1 3.52140214992811 -0.681092906142899 0.00122548554858776 180.707320942353 56.504042064902 3.19813086530673 0.00152201808674833 -251.560602330631 189.938178131338 -1.32443411222299 0.186306996182398 ITSN2 other 1 1 1 3.19813086530673 -1.32443411222299 0.00142106436043948 13.6496376569952 3.84995892116191 3.54539825917826 0.000450522306078967 -14.085513516735 13.5147731840035 -1.04223084804761 0.298091412432814 NTRK1 other 1 1 1 3.54539825917826 -1.04223084804761 0.000203673737734358 -25.9860409382359 102.134352549563 -0.254429976688065 0.799326814286581 -720.233854078177 187.346617923206 -3.84439207956988 0.000145795871116975 MGEA5 other 1 1 1 -0.254429976688065 -3.84439207956988 0.130411076217563 12.7227085577959 12.5424051967193 1.01437550120959 0.311169953684964 -36.4458074779453 33.1922132136362 -1.0980228176822 0.273020024825028 MT1F other 1 1 1 1.01437550120959 -1.0980228176822 1.22434269520778e-10 96.8616229106893 32.0024652709472 3.02669254042198 0.00267444808336576 -293.081744738893 73.78188896782 -3.97227217734587 8.81065023635226e-05 TCAF1 other 1.52602073530698e-06 1 1 3.02669254042198 -3.97227217734587 0.248876939397012 2.57143481409927 1.91869499476004 1.34019988644463 0.181158649668455 -2.23108706546528 4.09956529515494 -0.544225278739208 0.586676421435442 ZNF69 other 1 1 1 1.34019988644463 -0.544225278739208 0.225205167608885 717.107441555321 449.633221374214 1.59487201449133 0.111727993235279 -487.463162823774 1141.0130124884 -0.427219635086091 0.669506675664492 TXNRD1 essential 1 1 1 1.59487201449133 -0.427219635086091 0.0142903047180175 81.1761594994546 37.0951987020198 2.18831984569029 0.0293735336235677 -129.863542014644 78.1531197623333 -1.66165525329718 0.0975673700276629 NRARP other 1 1 1 2.18831984569029 -1.66165525329718 0.163160802242483 4.40866554147388 2.6296217041097 1.67653983635129 0.0946214600311208 -2.6625715580805 6.85776217648328 -0.388256619223545 0.698087570841497 ZNF583 other 1 1 1 1.67653983635129 -0.388256619223545 0.02044744297415 12.4553550410399 5.35897574643091 2.3242044059138 0.0207442268356781 -11.5484318428983 14.4216776645182 -0.800768961249985 0.423863272252621 ZNF568 other 1 1 1 2.3242044059138 -0.800768961249985 0.0105226209067625 28.4214612460538 14.1941246558345 2.00233983674162 0.0460996640595558 -64.9034683143689 36.3149878161232 -1.78723640616377 0.0748545784084932 ZNF480 other 1 1 1 2.00233983674162 -1.78723640616377 2.78301934427042e-05 73.9437838231862 18.3471048417355 4.03026986879047 6.97230514369127e-05 -54.101528615647 48.2282073948624 -1.12178186870388 0.262798879188797 ZNF587 other 0.255258534256483 1 0.734671792990749 4.03026986879047 -1.12178186870388 0.708390785216779 444.101515863126 712.325845217277 0.623452762306644 0.533448446550157 1496.41117915233 2243.51323768278 0.666994584216452 0.505274960593932 TPM2 other 1 1 1 0.623452762306644 0.666994584216452 0.00768103953521744 7.30171262156676 2.3653778259071 3.0869117574342 0.00219988261575464 4.79587919917353 7.57641645016434 0.63300100129389 0.527186498464702 FLVCR1-AS1 other 1 1 1 3.0869117574342 0.63300100129389 0.221860995116272 100.266961397604 81.5524217941687 1.22947864933637 0.219798452612221 -149.646355061119 174.769572110256 -0.856249478980884 0.392502519416093 SH3BGRL2 other 1 1 1 1.22947864933637 -0.856249478980884 0.986254092047064 -1.02460838607581 6.98152940084144 -0.146759875558545 0.883414552283091 1.03032041139252 22.3742463381063 0.0460493907067497 0.963299787992759 ZNF808 other 1 1 1 -0.146759875558545 0.0460493907067497 0.432980336110508 41.6551669485466 34.5586223672107 1.20534801723084 0.229000253053931 -69.1040428012245 133.335243265652 -0.518272897013013 0.60464241566244 ANKRD35 other 1 1 1 1.20534801723084 -0.518272897013013 0.15292116935969 -5.23720156653263 4.01490235531006 -1.30444058237331 0.193041749539962 -23.1851885799737 12.2658275498142 -1.89022619842107 0.059651391368825 B3GNT6 other 1 1 1 -1.30444058237331 -1.89022619842107 2.53314893143453e-05 149.09993510246 58.7584026979365 2.53750830955956 0.0116402407787776 -378.490470682786 117.739149152755 -3.21465267420723 0.00143968896862774 YTHDF2 other 0.233075033181291 1 1 2.53750830955956 -3.21465267420723 0.326962861626289 7.25821675128755 4.85330523074494 1.49552035287372 0.135767304359612 0.464777002593524 11.9278369390205 0.0389657408103107 0.968942076937383 NBR2 other 1 1 1 1.49552035287372 0.0389657408103107 1.12161837937506e-10 72.7268856792986 17.5220372401027 4.15059531507264 4.27238984239258e-05 -102.465146391373 30.0240655484466 -3.41276720922543 0.000727070082521277 TMA16 essential 1.39944325194626e-06 1 0.45859832568242 4.15059531507264 -3.41276720922543 0.437884889509762 -354.283938895737 364.648413477806 -0.971576800559151 0.331994938094782 339.106393036979 842.044412862943 0.402717942019258 0.687424634881703 HLA-DRB5 other 1 1 1 -0.971576800559151 0.402717942019258 0.011195698290369 19.7024796439851 6.68347178924033 2.9479408704476 0.00343650783000473 0.485682800753363 20.286211641494 0.0239415229090844 0.980914316740459 ATL1 other 1 1 1 2.9479408704476 0.0239415229090844 0.00109449917799855 7.50836284411357 3.97884933740215 1.88706890043137 0.0601005580454343 -16.3109573802405 8.55377480411219 -1.90687243395735 0.0574765336238263 CNGA1 other 1 1 1 1.88706890043137 -1.90687243395735 2.05346188297454e-08 243.977196983778 42.6203307357498 5.7244322784931 2.4068863848467e-08 -191.44682048695 190.712303562093 -1.00385143963519 0.316215868475685 MAFK other 0.000234957108649947 1 0.000307070564978742 5.7244322784931 -1.00385143963519 0.243443740297375 -2.61392862532973 2.28060606052933 -1.14615525695965 0.252587268639278 -8.2357246585701 5.78817913258974 -1.4228524152267 0.155753060556821 C1orf228 other 1 1 1 -1.14615525695965 -1.4228524152267 0.334241982414179 -2.35430991939464 9.6000595460478 -0.245239095455807 0.806428996917653 -32.2475061687778 22.1097867306416 -1.45851728746377 0.145681880962987 ZNF43 other 1 1 1 -0.245239095455807 -1.45851728746377 6.40322203847639e-07 213.317776323617 43.4430025954953 4.91029080816196 1.45260018807144e-06 -271.201491969067 154.073124983572 -1.76021283399025 0.0793270538821719 GPN1 essential 0.00671954120717712 1 0.0171711868231925 4.91029080816196 -1.76021283399025 0.324650213242186 -20.4144122977781 23.6859754892752 -0.861877624884884 0.389402276833626 -76.9907363898768 55.0409231636734 -1.39879078991702 0.162847210520856 PLN other 1 1 1 -0.861877624884884 -1.39879078991702 0.149589827075135 -0.0228953927796005 13.5761653266777 -0.00168644033338413 0.998655466760404 -48.3328710031897 26.5195062486596 -1.82254038027697 0.0693061512224259 C2CD4A other 1 1 1 -0.00168644033338413 -1.82254038027697 0.797263464666629 10.5225777960735 15.9559284538722 0.659477624664321 0.510067912790784 0.0852321302457865 51.6665735165513 0.00164965710796522 0.998684802291366 ZNF28 other 1 1 1 0.659477624664321 0.00164965710796522 0.322092104377194 6.16503505975374 31.7039654804727 0.194456275936553 0.84594318770781 110.107167917874 73.4136931700882 1.49981785636057 0.134656843633207 ITGBL1 other 1 1 1 0.194456275936553 1.49981785636057 0.00174728651337668 30.6809275044361 25.9802814864071 1.1809312967024 0.238535261125077 -134.774013376335 52.5011131957409 -2.56706963286387 0.0107251952982665 ZNF511 other 1 1 1 1.1809312967024 -2.56706963286387 0.00150690369495592 24.6913483089147 10.9850299859749 2.24772698303412 0.0252807910646447 -47.6609033563166 23.5671291210431 -2.02234659603745 0.0439800065580873 ZNF627 other 1 1 1 2.24772698303412 -2.02234659603745 0.053583662007727 8.06980259458521 3.71000061403077 2.17514858732535 0.0303554117351721 -0.954218446908845 6.88608203773398 -0.138572041645738 0.889876046929517 KCNRG other 1 1 1 2.17514858732535 -0.138572041645738 0.000950219724085689 85.7872347436405 24.877163578858 3.44843311705146 0.000640051991562704 -53.1198761038625 74.5776246229259 -0.712276321114321 0.47681758504424 WDHD1 essential 1 1 1 3.44843311705146 -0.712276321114321 0.000109109319810038 26.3893928440257 6.11478052225027 4.31567294165356 2.12739278609145e-05 13.2569977578936 26.7342466570729 0.495880730358499 0.620321097727454 ZNF789 other 0.936048854650316 1 0.233373914755537 4.31567294165356 0.495880730358499 1.02078313261339e-08 929.252536231881 417.962993280905 2.22328902599123 0.0268988127584917 -7721.09418564529 1523.02386763593 -5.06958186914703 6.78131888291801e-07 CTNND1 other 0.000118441466877132 0.0101780815113716 1 2.22328902599123 -5.06958186914703 1.95637409277556e-05 621.846268942252 140.304066031146 4.43213291341255 1.28353334166631e-05 41.1831867110298 327.838238604828 0.125620448933267 0.900111259731161 DDX39B other 0.181727589477922 1 0.142947108261377 4.43213291341255 0.125620448933267 0.537050141845854 -2.25125462420606 2.91586796918913 -0.772070151321739 0.440642685841649 -7.83887272170324 10.0108596367666 -0.783036922514985 0.434184541541903 SH2D1B other 1 1 1 -0.772070151321739 -0.783036922514985 0.00125676641937315 37.5915287666481 10.374157586681 3.62357410252862 0.000337834120779549 -18.7079472674663 51.5505364977435 -0.362904996503482 0.716915443189275 ARC other 1 1 1 3.62357410252862 -0.362904996503482 3.91158528691326e-12 176.660208955996 23.6399097081446 7.47296462368179 7.55403514585619e-13 8.70687699119024 95.7478773132012 0.0909354571141994 0.927600771041401 NUDT16 other 5.08388739740117e-08 1 1.06171963975009e-08 7.47296462368179 0.0909354571141994 4.86973810093921e-16 351.941930611939 40.4329922526453 8.70432562628144 1.76160456656884e-16 -73.0482175658758 125.067909836568 -0.584068428594761 0.559588353586246 TLK1 other 6.7927976770001e-12 1 2.56560089075087e-12 8.70432562628144 -0.584068428594761 4.44387630537768e-07 366.542349096387 93.9586117035814 3.90110435276275 0.000116948959247572 -328.997570229372 162.005110403068 -2.03078513641222 0.0431110776872364 LRBA other 0.00471539714763626 1 1 3.90110435276275 -2.03078513641222 0.000419059508673201 59.610511562719 16.7270618168887 3.56371682099796 0.00042169430001951 102.022150877593 40.2471294291465 2.53489260786162 0.0117272595466314 MMP17 other 1 1 1 3.56371682099796 2.53489260786162 5.55202118811463e-15 419.964047342067 53.1974533469992 7.89443894245658 5.04051859583266e-14 -236.297179372946 171.708809627252 -1.37615058823076 0.169765107124102 BAZ1A other 7.63236352730119e-11 1 7.1988686585682e-10 7.89443894245658 -1.37615058823076 0.000163448160912412 207.199061655754 53.5802818651368 3.86707673873909 0.000133434228262443 40.7322364618952 109.642703724807 0.371499744881606 0.710511199382109 AKR1C4 other 1 1 1 3.86707673873909 0.371499744881606 5.01571504111994e-11 108.985683506837 35.4693429360775 3.0726727501902 0.00230379580588148 -280.632681642692 64.0254201927056 -4.38314470718093 1.58841360800008e-05 COPS8 other 6.33685438295093e-07 0.232591404619452 1 3.0726727501902 -4.38314470718093 0.126216716589842 15.6883059917535 51.4219162335596 0.305089874918251 0.760496044520342 -134.044676125791 74.4478950626657 -1.8005166702559 0.0727206468525973 CCDC69 other 1 1 1 0.305089874918251 -1.8005166702559 0.000286395228344865 96.5749372365118 24.108941326362 4.00577262722489 7.69203733145443e-05 73.5958110305852 81.8747351230125 0.898883042736094 0.369390830139227 MDM4 other 1 1 0.80689471606957 4.00577262722489 0.898883042736094 0.530013264519847 9.94233244720091 11.2482486785548 0.883900483650967 0.377424056577789 24.2979227473771 36.8049442892158 0.660180940811711 0.509620164542384 RYR2 other 1 1 1 0.883900483650967 0.660180940811711 5.02711198701418e-20 205.343787876423 21.6054438029559 9.50426150692304 5.94405841875894e-19 -111.429869689301 54.3368660194956 -2.05072316186437 0.0411398367700617 KLHL9 other 7.29735576034979e-16 1 8.77937428450695e-15 9.50426150692304 -2.05072316186437 0.421858911583279 -181.723996358282 147.224223365014 -1.23433489547256 0.217983816931856 -59.8712571023735 212.503615753732 -0.281742298313444 0.778323230250882 FAM3D other 1 1 1 -1.23433489547256 -0.281742298313444 1.10964618538654e-13 358.251451558025 44.422037627217 8.06472351773722 1.60408278611051e-14 64.7909384954799 272.590995242972 0.237685542171813 0.812281507052183 NCOA6 other 1.49003289773705e-09 1 2.30105675667553e-10 8.06472351773722 0.237685542171813 0.0101075866855724 27.2913833940175 37.7855878901378 0.722269651417564 0.470656189188588 -320.023693237717 113.721114177259 -2.81410972406487 0.00519400357494161 STK39 other 1 1 1 0.722269651417564 -2.81410972406487 2.31562666258778e-10 329.963758306161 55.4640993143287 5.94914119917779 7.0664424393895e-09 -146.294942424368 128.739049846314 -1.13636804527462 0.256652850742173 C6orf89 other 2.86790362161497e-06 1 9.17648215179121e-05 5.94914119917779 -1.13636804527462 9.85085992269092e-12 243.698492566253 61.8594698314737 3.93955029408061 0.000100319160347623 -363.420197381912 87.8999450011263 -4.13447582222327 4.55308410136376e-05 TTC37 other 1.26672207745882e-07 0.657692998441995 1 3.93955029408061 -4.13447582222327 1.77484785539226e-19 166.063086718124 23.5716109812633 7.04504612986038 1.23074379082146e-11 -268.839722660709 52.6511752994338 -5.10605359010096 5.79328286695908e-07 TUSC1 other 2.56447766625628e-15 0.00870556616417941 1.70002639826168e-07 7.04504612986038 -5.10605359010096 0.2319496430489 -99.9332369397118 59.8661341891838 -1.66927827048113 0.0960525780477767 -39.6919146108185 123.025085255626 -0.322632693392124 0.747186792583372 PAPSS2 other 1 1 1 -1.66927827048113 -0.322632693392124 2.29046203612981e-05 57.4696619080834 25.7549399859167 2.23140344879503 0.0263555502822171 -163.732443799586 55.1454885408687 -2.96909952440159 0.00321524784532467 FAN1 other 0.211615787518033 1 1 2.23140344879503 -2.96909952440159 0.3490745190418 -38.8835008794761 44.3987425047023 -0.875779328105022 0.381808971271206 77.9708270087647 94.5073548721949 0.825023905432619 0.40997452654589 ABCA4 other 1 1 1 -0.875779328105022 0.825023905432619 1.90874103604428e-07 416.845091769985 74.1609391469755 5.62081732735156 4.14914503768313e-08 -202.128038912128 252.231524365866 -0.801359145809777 0.423520248071436 IPO9 essential 0.00207384713566211 1 0.00052428596696164 5.62081732735156 -0.801359145809777 0.20035706927861 10.5070102105368 18.2501077374007 0.575723188143396 0.565208207964071 -69.781553633402 44.1290991139938 -1.58130474073679 0.114799332197276 CEP290 other 1 1 1 0.575723188143396 -1.58130474073679 4.84154664260436e-12 322.875352654069 42.9208830082601 7.52257013426149 5.47567754536516e-13 -29.0882162587384 149.453683281818 -0.194630306995432 0.84580588100639 GLMP other 6.28045430478638e-08 1 7.707563712856e-09 7.52257013426149 -0.194630306995432 8.06171918142555e-05 52.0513050288085 12.0266019280253 4.32801429200999 2.04235102424983e-05 4.64524305920722 35.7402050018825 0.129972479423734 0.896673875926459 TOGARAM1 other 0.701450185975837 1 0.224373839806749 4.32801429200999 0.129972479423734 0.0034635234155746 136.263714582922 52.2704353946395 2.60689840354565 0.00956985172239743 -179.96055272062 120.755669472079 -1.49028657211188 0.137146353877488 DLL1 other 1 1 1 2.60689840354565 -1.49028657211188 2.30669164433124e-07 123.052939479016 22.9412143563669 5.36383722184545 1.57727011563647e-07 -54.8190394628287 55.3829778363591 -0.989817478301786 0.323020638288006 ANKRD13B other 0.0024951483516731 1 0.00194903268189199 5.36383722184545 -0.989817478301786 0.000111387284715459 111.988082996858 34.6107386906171 3.23564556070042 0.00134144088150607 -102.17084952923 77.5271815366841 -1.31787132595404 0.188495303954446 ECI2 other 0.954589030011486 1 1 3.23564556070042 -1.31787132595404 1.43972090146897e-12 122.380121765316 29.0658335728349 4.21044596772524 3.34630243553447e-05 -503.262032385193 91.482600554798 -5.50117759369706 7.9227835307568e-08 UNC13B other 1.8907854598992e-08 0.00119832100902697 0.362170312597896 4.21044596772524 -5.50117759369706 0.00305601592006843 139.304316926946 66.8414795002018 2.08409984292052 0.0379465006903893 -188.044765566632 122.82159232964 -1.53103995803881 0.126750564046663 LDB1 other 1 1 1 2.08409984292052 -1.53103995803881 2.53589211986146e-05 428.058969424559 108.34548419569 3.95087042715516 9.58411544340488e-05 -358.257830794421 238.766829097515 -1.50045059503682 0.13448370726344 PPP1R14C other 0.233302075027255 1 0.995214547643163 3.95087042715516 -1.50045059503682 7.37638796936825e-19 194.158794636382 45.3748500616093 4.2789958396062 2.48940419606924e-05 -541.395836873848 94.0177541633636 -5.75844255897804 2.00652885753973e-08 CTR9 essential 1.0602082428373e-14 0.000304430558265928 0.271768256084878 4.2789958396062 -5.75844255897804 0.533780148208033 -78.0746717722394 70.381776116682 -1.1093023802469 0.268137949072451 -22.340366793612 213.16104696923 -0.10480510914753 0.916596528538383 SMOC1 other 1 1 1 -1.1093023802469 -0.10480510914753 0.533521825890863 -5.37578739795407 11.8957683269271 -0.451907539741296 0.651642704343456 -38.8808324564299 38.5504972519709 -1.00856889607156 0.31394582789595 F5 other 1 1 1 -0.451907539741296 -1.00856889607156 0.000475629841852699 203.842727965928 77.9324531197926 2.61563340823616 0.00932957315711858 -468.690638471982 221.395595553106 -2.1169826676139 0.035035085105858 MSRB1 other 1 1 1 2.61563340823616 -2.1169826676139 0.0333720249741101 71.9807340002004 27.7791525219883 2.59117818454774 0.010005682605302 -15.7143207857867 66.2562383135436 -0.237174961720918 0.812673779789397 ZNF652 other 1 1 1 2.59117818454774 -0.237174961720918 7.45135900617614e-28 600.942141962141 50.3437849025309 11.9367692183972 2.23875545707399e-27 -166.673808453452 220.125358107885 -0.757176773662598 0.449506387246977 SMURF1 other 1.12083342170901e-23 1 3.38678925546153e-23 11.9367692183972 -0.757176773662598 2.38793167587195e-05 206.590524559826 80.4020315505224 2.56946896211211 0.0106497576781651 -393.753850502622 136.13822532959 -2.89230926544948 0.00409302115262341 SLC5A3 other 0.220095662565118 1 1 2.56946896211211 -2.89230926544948 1.52245333980029e-07 53.506804643088 18.3441603942849 2.91683039686886 0.00378604330054327 -145.275678251694 36.0615574868031 -4.02854697290482 7.0163277041524e-05 GPATCH3 other 0.00166297578306385 1 1 2.91683039686886 -4.02854697290482 3.33688663286984e-20 1022.75049597712 112.335697390849 9.10441221919571 1.02138769648739e-17 -558.066911999515 331.80287318363 -1.68192308476685 0.0935747804851228 CDC42BPB other 4.84916365488646e-16 1 1.49766077935946e-13 9.10441221919571 -1.68192308476685 0.12088460564184 5.92900497191196 3.22445120865086 1.83876405262547 0.0668851817133642 -4.99164783366694 8.22776804308692 -0.606683101361977 0.544495478298474 OXCT2 other 1 1 1 1.83876405262547 -0.606683101361977 0.26891932694992 325.776677551487 312.534270819769 1.04237105485099 0.298026530082427 -574.298931331126 723.18440568435 -0.794125159249895 0.427711078188815 RPL10A essential 1 1 1 1.04237105485099 -0.794125159249895 0.425416267642814 20.2276621902158 20.310043608769 0.995943808878988 0.320032303155881 56.4846842169124 69.0876093859392 0.817580528823569 0.414206972490576 COLGALT2 other 1 1 1 0.995943808878988 0.817580528823569 0.0105446519703007 39.2212240490593 14.4600079476407 2.71239298007844 0.00704114690203115 -48.6865336824614 67.6435992016741 -0.719750785840154 0.472203792256585 APCDD1L other 1 1 1 2.71239298007844 -0.719750785840154 0.88700118518294 -11.0561474488876 22.892140800854 -0.482966951193799 0.629451528240323 7.47268412133378 75.4688234470951 0.0990168360922211 0.921187290041697 RCSD1 other 1 1 1 -0.482966951193799 0.0990168360922211 0.468005237125831 36.8787300960096 86.1790305300649 0.427931596226809 0.668988776382968 -219.590271252558 205.763938855857 -1.06719511919135 0.286688192125753 RASSF9 other 1 1 1 0.427931596226809 -1.06719511919135 0.252621993486641 24.4641165427559 16.0430415343863 1.52490514285088 0.128270439009599 -0.0621957132554473 22.0679422601028 -0.00281837393456899 0.997753022071927 FAM169A other 1 1 1 1.52490514285088 -0.00281837393456899 0.000291533875761986 33.5773423181661 9.3495910409151 3.59131668660448 0.00038136001522174 -33.79759821598 23.0141155980404 -1.46855950523068 0.142947031337403 ZNF830 essential 1 1 1 3.59131668660448 -1.46855950523068 0.0093885168897726 -1.36855882991425 1.30578162689775 -1.04807634119163 0.295394381035746 -7.50493975903615 2.49888637694443 -3.00331372737843 0.00288113484858343 GRIN3A other 1 1 1 -1.04807634119163 -3.00331372737843 5.7836992804896e-40 336.40521389472 49.8676359507627 6.74596273677127 7.12696726374616e-11 -617.625417474558 92.7290612695303 -6.66053779709191 1.1901529778118e-10 CNOT7 other 8.83344391109177e-36 1.81986291837203e-06 9.7062167164959e-07 6.74596273677127 -6.66053779709191 4.70809872960355e-11 574.923726845567 92.6118190013078 6.20788721186275 1.68071004870417e-09 -529.706832851115 254.675651961521 -2.07992726737438 0.0383353657604473 TMEM184B other 5.95292003371073e-07 1 2.2225709684064e-05 6.20788721186275 -2.07992726737438 1.42709742920649e-08 361.293899925502 73.8984937492179 4.88905634736738 1.6084067807359e-06 -320.642194438022 154.724787109401 -2.07233889558565 0.0390368460767558 MTOR essential 0.000164358810921712 1 0.018964724351657 4.88905634736738 -2.07233889558565 0.224609693292829 -43.4566126839787 27.8457543993348 -1.56061897482716 0.119602074865152 5.16820861066842 54.0236064468095 0.0956657459689762 0.92384592719952 SCAMP5 other 1 1 1 -1.56061897482716 0.0956657459689762 0.417359148293982 18.3620633998322 23.6744367516262 0.775607191523614 0.438619577099807 -28.8874362450769 50.0399258854024 -0.577287750410197 0.564197657642447 ZNF521 other 1 1 1 0.775607191523614 -0.577287750410197 0.00186873624328134 48.9309244446687 20.1385141034579 2.42971870681695 0.0156603190941657 -17.8731777312374 30.5051453603683 -0.585906984546216 0.558351028145331 ALPK2 other 1 1 1 2.42971870681695 -0.585906984546216 2.47077835120514e-06 39.5121468321913 19.1630738312983 2.06188981893174 0.0400278882403291 -113.604529887921 34.9413590488539 -3.25129110545135 0.00127161637213048 LRIG2 other 0.0248016730893972 1 1 2.06188981893174 -3.25129110545135 3.84084534580156e-13 629.323039098426 95.920240516605 6.56089930247289 2.16035348651952e-10 -823.347203912029 271.241388767177 -3.03547776264616 0.00259926803978725 PNP other 5.10294712643195e-09 1 2.91647720680135e-06 6.56089930247289 -3.03547776264616 0.243249353950233 123.977227096233 78.1876825389994 1.5856362929595 0.113844642266577 -50.1519705384274 252.334451145549 -0.198751975050364 0.842587471884301 PAX9 other 1 1 1 1.5856362929595 -0.198751975050364 7.78157087223939e-10 214.448670993369 33.0151293798573 6.49546662458956 3.17563401396244e-10 -51.4739203797885 103.816870521459 -0.495814602397869 0.620366631262671 FOXJ3 other 9.45305229559641e-06 1 4.27186287558228e-06 6.49546662458956 -0.495814602397869 0.000395722173847273 264.000385064196 84.3822426261313 3.12862489604466 0.0019178362399649 -131.592068614847 152.803271652391 -0.861186198383259 0.389780318059306 ZNF358 other 1 1 1 3.12862489604466 -0.861186198383259 2.90030563029565e-10 131.117508748579 23.2260599988331 5.64527555492262 3.65546997753116e-08 -131.462812185817 53.6642436184897 -2.44972822351533 0.0148353300377094 SFT2D1 other 3.57955720891089e-06 1 0.000462892163254771 5.64527555492262 -2.44972822351533 0.00962003461773924 -45.0001604681228 17.2741005273405 -2.60506533448146 0.00961871442979187 97.8712909408174 56.9455540439655 1.71868186347357 0.0866486306109182 CD247 other 1 1 1 -2.60506533448146 1.71868186347357 1.98436503671206e-09 109.198771386896 18.0146737105699 6.06165691043435 3.93371571129248e-09 -41.4386414670715 43.6635378831672 -0.949044522639257 0.343342022814996 CHAMP1 other 2.37111778236724e-05 1 5.15002060922412e-05 6.06165691043435 -0.949044522639257 0.0806303146039551 -89.0951836255464 60.5479037254354 -1.47148254759675 0.142143371507437 -258.095903030625 118.836010654851 -2.17186610025343 0.0305998461028979 INPP5F other 1 1 1 -1.47148254759675 -2.17186610025343 0.0276653566924243 34.7101484747041 47.6990485267536 0.727690583916696 0.467338448385192 -218.67858317053 102.987151069704 -2.12335792280071 0.0344957954383664 ARHGAP11A other 1 1 1 0.727690583916696 -2.12335792280071 0.935191118324684 0.142927887825504 2.01202821100725 0.0710367215745708 0.943413323873743 -4.3167399287781 12.1680846296348 -0.354759196715716 0.72300589337518 SUCNR1 other 1 1 1 0.0710367215745708 -0.354759196715716 0.00157105301595404 -126.802259971453 296.761682657334 -0.427286497488523 0.66945803146862 -2088.34855504766 582.120362519801 -3.58748583541712 0.000386088273538943 HMGN2 essential 1 1 1 -0.427286497488523 -3.58748583541712 0.00937786549727616 333.544251254951 116.360041948288 2.86648445351353 0.00442825882326907 569.33258443039 326.766196499541 1.74232399351378 0.082421585232954 SELENOM other 1 1 1 2.86648445351353 1.74232399351378 0.00113258988576748 59.7841808262445 48.0774388935919 1.24349761971645 0.214594737788612 -350.572658584051 115.012865281957 -3.04811690174498 0.00249476746145188 UBE2J1 other 1 1 1 1.24349761971645 -3.04811690174498 0.0170018315951969 8.20683429621846 2.85910165332601 2.87042410215509 0.00437222715117402 -2.07773890806325 9.64636414105503 -0.215390884864108 0.829599791203037 GJC2 other 1 1 1 2.87042410215509 -0.215390884864108 1.70310307801407e-29 619.157924875316 48.8763957074005 12.6678310852117 4.54286530742377e-30 568.304469091581 294.729206000826 1.9282258341577 0.0547143408181636 OPA1 essential 2.57083409626224e-25 1 6.90152097503819e-26 12.6678310852117 1.9282258341577 8.46679001244445e-07 156.254698791966 28.9078720597375 5.40526464449093 1.2671316296626e-07 -17.6477903774083 102.83334306912 -0.171615449334816 0.863848334240052 DENND4B other 0.00881138836595094 1 0.00157098979445569 5.40526464449093 -0.171615449334816 0.134951330989015 0.455077838297236 25.9468469076513 0.0175388493221132 0.986017739232278 -100.819832348283 54.6279085241338 -1.84557371995566 0.0658835787482299 RYR3 other 1 1 1 0.0175388493221132 -1.84557371995566 3.23292208812217e-16 83.2548882967824 11.4049841457068 7.29986883218262 2.37927629010184e-12 -85.511744209879 32.1067546587768 -2.66335682689447 0.00813553638620342 ZNF277 other 4.51800861815073e-12 1 3.32337312201425e-08 7.29986883218262 -2.66335682689447 1.22034678366899e-06 31.5102098963711 7.28702807464061 4.32415102200978 2.04978253371215e-05 -36.16222567463 17.733491997774 -2.03920500706625 0.042253437200627 KTI12 essential 0.0125659108314396 1 0.22516861132828 4.32415102200978 -2.03920500706625 0.110953871636357 48.161716544667 24.5346163616227 1.96301078585448 0.0505190197153405 -67.0726193948433 80.8804672496508 -0.829280810010811 0.407569532878045 DUSP27 other 1 1 1 1.96301078585448 -0.829280810010811 2.54811975385319e-19 421.755725143581 42.7657179122959 9.86200502955472 3.42300886244869e-20 -89.8215552661825 259.782331689701 -0.345756983094103 0.729753978344726 SELENOT other 3.67668199283477e-15 1 5.08932957668872e-16 9.86200502955472 -0.345756983094103 0.177907089426014 -1.88601762432315 6.96097834079315 -0.270941458511743 0.786611288118125 24.1904529758219 13.201617424973 1.8323855477028 0.0678260621270236 ARHGEF15 other 1 1 1 -0.270941458511743 1.8323855477028 0.000218224023532466 28.9147458304849 7.50800539613314 3.85118873853991 0.000142651636414262 -34.5962729113727 34.9370896174321 -0.990244845526877 0.322821791324979 TOX other 1 1 1 3.85118873853991 -0.990244845526877 0.769306994711793 -250.950113946761 766.685139646136 -0.327318348784727 0.743641805359223 -1464.20460716653 2021.13995837257 -0.724444935691399 0.469323609259314 CES1 other 1 1 1 -0.327318348784727 -0.724444935691399 2.50594190019408e-05 -122.788384813623 44.6284668606561 -2.75134669530564 0.0062742766215381 99.7073459386606 84.3836180000029 1.18159600526559 0.238246146024615 CD3E other 0.230646892493863 1 1 -2.75134669530564 1.18159600526559 0.000346772704499389 58.8244179963543 14.6984406542553 4.00208562119303 7.87147252341665e-05 12.0137909491329 46.2970980854762 0.259493390427029 0.795427941155189 RUSC2 other 1 1 0.824694176278363 4.00208562119303 0.259493390427029 0.202935890324158 -14.544331076571 9.7240577598315 -1.49570595278149 0.135718928634409 -38.101603227184 39.4089605686193 -0.966825886230648 0.334363486513446 C1orf68 other 1 1 1 -1.49570595278149 -0.966825886230648 0.0511568626795612 3.27517139869077 5.35944105322546 0.611103166573627 0.541565122875725 -33.9076286942713 15.030456906532 -2.2559280070545 0.0247500020263162 FICD other 1 1 1 0.611103166573627 -2.2559280070545 4.78162200493667e-07 371.045898229946 79.2702964965799 4.68076839154947 4.2366205019638e-06 -153.082695224177 143.933729057175 -1.06356374024999 0.288333331182221 OSTC essential 0.00506278137882695 1 0.0487211357725837 4.68076839154947 -1.06356374024999 1.58777582883535e-21 521.330286475938 90.8658102369823 5.73736463820973 2.2406184000195e-08 -694.920502430242 147.97415034891 -4.69622904265157 3.94768017109509e-06 R3HDM4 other 2.32799692023839e-17 0.0586546319821308 0.00028605975113049 5.73736463820973 -4.69622904265157 0.000337997803222591 109.27905960658 27.7121183552205 3.94336723760395 9.88085300131265e-05 72.4244741669138 92.6891037918069 0.781369882802941 0.435164486603238 TSEN15 other 1 1 1 3.94336723760395 0.781369882802941 9.50214438563732e-05 113.619322659048 38.6309489277842 2.94114759830117 0.00352119182553498 -129.447366462288 62.9217929893925 -2.05727396363468 0.0405126356356417 LTN1 other 0.820700210587496 1 1 2.94114759830117 -2.05727396363468 9.1134739662827e-07 64.0001005838653 14.1637836202914 4.51857372998673 8.77163805069731e-06 -88.8565975549388 34.6865388484989 -2.56170262311381 0.0108738735755288 RUNDC1 other 0.00946707675617447 1 0.0989177622977136 4.51857372998673 -2.56170262311381 0.0587997157449003 292.716822954765 152.794886814907 1.9157501213333 0.0563136232612555 -1348.54448981455 1076.74305986582 -1.25242923783749 0.2113544758739 CCDC152 other 1 1 1 1.9157501213333 -1.25242923783749 0.0444088451578735 -4.13488256671638 29.3520951979325 -0.140871802807713 0.888059853297495 -132.788443301724 57.1383570023356 -2.32398077698133 0.0207524171712786 GRK5 other 1 1 1 -0.140871802807713 -2.32398077698133 8.81568892373866e-15 136.117347706192 17.1633996413464 7.93067518968018 4.16006174572081e-14 -74.4367054855398 65.1460474437085 -1.14261276633643 0.254095543300738 TYW1 other 1.20836648077686e-10 1 5.9451442408096e-10 7.93067518968018 -1.14261276633643 7.72225024545638e-35 408.77010876343 32.3332778839969 12.6423961786363 6.78640113772198e-30 -403.048489255759 107.882241167373 -3.73600404380229 0.000222036986792165 DCAF12 other 1.17439981732901e-30 1 1.03071860479721e-25 12.6423961786363 -3.73600404380229 0.21524369116333 14.7009216917374 11.6566944938842 1.26115698575187 0.208176708670387 -10.6692890492819 23.6177878217257 -0.451748026945494 0.651758468828171 SFMBT2 other 1 1 1 1.26115698575187 -0.451748026945494 7.85564658882906e-07 45.4882487588809 8.95418948418568 5.0801079024762 6.58376597672142e-07 -33.8581408484198 29.7515483691033 -1.13802953810569 0.256001304580471 ITPRIPL1 other 0.00819579608612536 1 0.00791171157422613 5.0801079024762 -1.13802953810569 3.07621163791909e-05 109.740495873097 37.3290548333738 2.93981447863996 0.00352389229572266 -215.592798950899 72.4630386635878 -2.97521057530855 0.00315144760890305 SMC5 essential 0.280858122542013 1 1 2.93981447863996 -2.97521057530855 0.0466703830102948 9.27461390014115 22.0472584956013 0.420669712834888 0.674278644849321 -88.8840162321573 42.67005490896 -2.08305371112829 0.0380399274579121 PRMT6 other 1 1 1 0.420669712834888 -2.08305371112829 0.0232929444910766 55.0122556042651 20.7204961101111 2.65496807180309 0.00832832951057621 -47.7412647923589 70.4735046692857 -0.677435654951411 0.498619050982943 SHISA4 other 1 1 1 2.65496807180309 -0.677435654951411 7.09095612235446e-07 112.008186307427 21.1896069593427 5.28599640957671 2.31913626245945e-07 -5.10871887315086 69.0890128644133 -0.0739440131121381 0.94110113439203 CIPC other 0.00741359462592159 1 0.00284581210766399 5.28599640957671 -0.0739440131121381 1.02356317213691e-08 297.40245943845 62.0304372019654 4.79446015300739 2.51584172036502e-06 -274.876704716619 160.466075706167 -1.71298951200098 0.087695319450914 CAPZA2 other 0.000118733327967881 1 0.0293321986177358 4.79446015300739 -1.71298951200098 4.03054092857606e-08 364.83204702678 64.8237759963239 5.62805917149087 4.02184231493603e-08 -216.133491306104 295.226047184888 -0.732094926470863 0.46465324087775 TOP1 essential 0.00045387921396695 1 0.000508441305454213 5.62805917149087 -0.732094926470863 0.00911925109456736 152.303057520551 108.78680571091 1.40001405984179 0.162477866886526 -499.687270811996 225.029234182315 -2.22054380013202 0.0270819076837027 PRC1 essential 1 1 1 1.40001405984179 -2.22054380013202 0.0246258114967587 52.9979863868407 22.7009259653051 2.33461782430549 0.0201835507267648 -59.8524106636415 52.348246017791 -1.14335083248635 0.253750259463809 MAP3K3 other 1 1 1 2.33461782430549 -1.14335083248635 0.000102858105407168 578.594565907798 239.416492064396 2.41668633985403 0.0162233609831236 -1850.08602725682 623.235700107033 -2.96851741153322 0.00321898383350518 SREBF2 other 0.884579706501645 1 1 2.41668633985403 -2.96851741153322 1.49719334695683e-08 81.2437330113365 18.2626265467374 4.44863354147985 1.19411404581455e-05 -113.667670406271 40.4552498246484 -2.80971371821849 0.00526371113513219 C1orf174 other 0.000172311982301262 1 0.133239245231987 4.44863354147985 -2.80971371821849 0.000286257509888464 94.9357976174339 31.3809838087091 3.02526517957944 0.00269771390288229 -87.8438458600767 64.8631172205266 -1.35429577893117 0.176654466222721 RASGEF1A other 1 1 1 3.02526517957944 -1.35429577893117 3.05106991341444e-11 238.515699582629 40.1482557053922 5.94087328059421 7.39500286900810e-09 -264.028458363626 78.4235864018496 -3.3666970675215 0.000853471927537276 SPOUT1 other 3.87790985994976e-07 1 9.5957557228249e-05 5.94087328059421 -3.3666970675215 0.00260823774005261 38.9857748584892 11.1982058838741 3.48143044187376 0.000568709675592852 31.6861145191423 45.2328782130363 0.700510685389244 0.484122256179323 DZIP3 other 1 1 1 3.48143044187376 0.700510685389244 3.03237610562318e-13 105.999596636959 13.8250791040831 7.66719639279698 2.12577480109993e-13 -46.1345296300739 26.3892826577505 -1.74822977298795 0.0813832412156199 KIAA0753 other 4.03760878463727e-09 1 3.00967196339728e-09 7.66719639279698 -1.74822977298795 0.120113349172581 -4.4864786714293 16.3340952053034 -0.27466955561595 0.78374736449681 -61.1558044133877 31.0426943915499 -1.97005464931661 0.0496940887751224 DCLRE1A other 1 1 1 -0.27466955561595 -1.97005464931661 6.6577196090833e-13 429.78644788939 108.541390103587 3.9596549065681 9.25425958161659e-05 -791.599264746707 190.517915340723 -4.15498596723048 4.1792822544811e-05 ATG9A other 8.80416841105176e-09 0.604491385288147 0.962628081679758 3.9596549065681 -4.15498596723048 0.000166625074189555 40.1166645279065 9.56087259307944 4.19592083644589 3.52415699859786e-05 -21.2584367182317 32.8247213336425 -0.647634948737361 0.517685444997612 NOS1AP other 1 1 0.380714680558527 4.19592083644589 -0.647634948737361 1.33486570594006e-07 248.406491196603 119.082696493954 2.08599988503968 0.0377703272314312 -1162.10642367958 302.986200591866 -3.8355094106909 0.000150925368921248 APRT other 0.00146239623001612 1 1 2.08599988503968 -3.8355094106909 5.86838661313928e-05 68.3906751831098 15.3936824270918 4.44277550267939 1.22634213352098e-05 35.3253446547417 36.6078383227847 0.964966692194857 0.335292446911638 TBKBP1 other 0.519234847530564 1 0.13676167473026 4.44277550267939 0.964966692194857 0.00926633341734561 40.8339654950482 21.5595982230587 1.89400401030549 0.0591261219050184 -80.8999297149941 50.1172254659796 -1.61421405440551 0.107466592998019 CCDC167 other 1 1 1 1.89400401030549 -1.61421405440551 0.0656672878033652 3.81962109327857 5.60736768200426 0.681178996971589 0.49625241289214 -15.3230883713447 8.39193419420505 -1.82593047284927 0.0687954227576646 SOWAHA other 1 1 1 0.681178996971589 -1.82593047284927 0.0197735524055788 4.17015096285184 8.51711414136622 0.489620180455033 0.624738161435813 -51.8279092414459 20.0977751499532 -2.57878839099096 0.0103611025638511 L3MBTL3 other 1 1 1 0.489620180455033 -2.57878839099096 0.00381988000813245 47.1453167411365 14.1547287018376 3.33071143461874 0.000967856783895132 44.6694554641496 24.1850095096258 1.84698936944271 0.0656746137423633 MFAP3L other 1 1 1 3.33071143461874 1.84698936944271 2.36495496507102e-05 141.210133345033 38.2765605336195 3.68920643277246 0.000264402556983606 -197.788504719242 99.6394141279255 -1.98504283119634 0.0479958892183749 NAGA other 0.2181197964285 1 1 3.68920643277246 -1.98504283119634 0.00356129011652752 255.202206211002 75.8660320814104 3.36385335056339 0.000862007716459603 -125.192060143386 264.171124540036 -0.473905164167222 0.635890710817547 SMG5 essential 1 1 1 3.36385335056339 -0.473905164167222 1.56942106070175e-06 25.5596142194467 22.709236689334 1.12551621919778 0.261213784066966 -204.602765284239 47.5669412637729 -4.30136476822538 2.25752081921532e-05 KIF1BP other 0.0160049559770365 0.329123960233401 1 1.12551621919778 -4.30136476822538 0.507409189292605 197.293131284804 182.629983846754 1.08028882842345 0.280837381185304 -186.481026401186 922.724423598839 -0.202098288104119 0.839969931381259 TGM2 other 1 1 1 1.08028882842345 -0.202098288104119 6.39388317525382e-07 376.568688971645 113.287853830576 3.32399878926835 0.000990314698759525 -440.576109450956 160.413265652429 -2.74650670353885 0.00636431184538759 PJA2 other 0.00671038039242888 1 1 3.32399878926835 -2.74650670353885 0.0398222981926979 -31.0897223489139 33.7780904314729 -0.920410892142852 0.358051405661809 -163.481294602352 65.0388599713819 -2.5135940985787 0.0124415178531675 RORB other 1 1 1 -0.920410892142852 -2.5135940985787 3.99172270611784e-05 56.737562455936 40.3178240116713 1.40725755535595 0.160324619883758 -294.58890966496 84.1780127094633 -3.49959449246824 0.000532248432729058 SGMS1 other 0.360173139773013 1 1 1.40725755535595 -3.49959449246824 5.0621160157339e-06 5.16411280113192 1.39000522791454 3.71517509245614 0.000239809445635344 -4.20348289284309 2.60190340180458 -1.61554148779225 0.107185139425522 SNORA31 other 0.0495884884901293 1 1 3.71517509245614 -1.61554148779225 4.12416480212918e-09 5.91677037125185 0.960153243062473 6.16231879025885 2.15389994090623e-09 -2.22756056175072 2.01367970667701 -1.10621393976635 0.269464858362289 SNORD36A other 4.87311313019584e-05 1 2.84120941204941e-05 6.16231879025885 -1.10621393976635 0.0486429947528209 -19.3736846882256 8.77342859223657 -2.20822275858825 0.0279419432625973 10.1383271424542 23.5918594246902 0.429738366948894 0.667677012452763 RN7SK other 1 1 1 -2.20822275858825 0.429738366948894 0.524151325340987 11.7122159388841 11.709338633507 1.00024572740332 0.317949725071415 -12.9766312978088 37.2792541648099 -0.348092567529375 0.728000257351866 ZNF525 other 1 1 1 1.00024572740332 -0.348092567529375 1.16854567027492e-14 611.916031707693 87.4577121142939 6.99670751629098 1.75404481447492e-11 -641.591158830186 263.179548396025 -2.43784580808209 0.015363467001593 INF2 other 1.59798620410095e-10 1 2.41567051849486e-07 6.99670751629098 -2.43784580808209 8.51243828344226e-06 104.477150349855 21.4521978687513 4.87023059311064 1.77246300846316e-06 149.925679963232 87.4329886851016 1.71474957242059 0.087380954959369 GP1BB other 0.0817619697124629 1 0.0208353026644844 4.87023059311064 1.71474957242059 0.183289594792449 8.33886586147035 5.16972066779844 1.61302058608546 0.107735061259998 -16.0352636218134 16.942636341918 -0.946444419758943 0.344642829444163 EFCAB2 other 1 1 1 1.61302058608546 -0.946444419758943 3.55293146816692e-06 161.22430347727 33.0660728750751 4.87582254132148 1.71677890286292e-06 149.969515996865 108.45876680002 1.38273300002925 0.167720014287294 COX20 other 0.0352237625754069 1 0.020201337349988 4.87582254132148 1.38273300002925 0.00407449510638183 102.988911665252 30.8409530167386 3.33935568104384 0.000939549092538245 8.28067866082156 97.4965553417658 0.0849330382165231 0.93236807164664 CHML other 1 1 1 3.33935568104384 0.0849330382165231 0.525211282235191 -4.34419696744215 4.5747725465407 -0.949598460523922 0.343032931892105 -9.31163913553913 15.6814494402089 -0.593799646585161 0.553065635668471 STUM other 1 1 1 -0.949598460523922 -0.593799646585161 0.00333418657227419 23.0293096077803 7.06787788523761 3.25830609720645 0.00124158902143593 23.4089362687473 22.6387453585481 1.0340209184741 0.301909632288353 TATDN3 other 1 1 1 3.25830609720645 1.0340209184741 0.00157601694692943 10.4184983991078 2.91646669277374 3.57230151982267 0.000408265929039676 6.83859169454735 9.84232493949249 0.694814663871479 0.487675635606837 SERTAD4-AS1 other 1 1 1 3.57230151982267 0.694814663871479 0.96879679674328 0.834570214456066 6.58090918440576 0.126816856314273 0.89916550216501 -4.91318326496169 22.6735044669694 -0.216692716034223 0.828586772793923 CR1 other 1 1 1 0.126816856314273 -0.216692716034223 0.00855923987353717 -0.954785449066183 18.6932437579123 -0.0510764991582614 0.959296429823185 -124.311724244871 40.9728149549169 -3.03400497089724 0.00261099560560609 RAET1G other 1 1 1 -0.0510764991582614 -3.03400497089724 7.62191557344503e-05 13.4390453715438 3.0552060777363 4.39873613419268 1.4873394841389e-05 -3.86884484867321 10.5123569742789 -0.368028298329222 0.7130969824053 C1orf53 other 0.665164572094548 1 0.164901328606479 4.39873613419268 -0.368028298329222 0.0153313769759647 49.5878096751064 22.1535223166513 2.23837135089956 0.0258842346637405 -61.3558344369153 48.5147693298307 -1.26468362695458 0.206905034176548 SAMD5 other 1 1 1 2.23837135089956 -1.26468362695458 0.737407489615411 -59.5477861074428 76.5649939706812 -0.777741667820743 0.437295942272012 -12.4523918925821 262.865608398422 -0.0473717043794796 0.962246530819397 FCGR3A other 1 1 1 -0.777741667820743 -0.0473717043794796 0.747505385959397 -9.3976289815523 70.449863823153 -0.133394565604026 0.893966251779404 -127.366762773594 167.248767392395 -0.761540815872015 0.44690206760744 CENPW essential 1 1 1 -0.133394565604026 -0.761540815872015 0.536296553652339 -13.7694500500592 13.9910959982739 -0.984158071087346 0.325812767994067 -25.504398475846 28.2825531339036 -0.90177143326119 0.367885219612363 SPRN other 1 1 1 -0.984158071087346 -0.90177143326119 0.189323447041816 17.3783445125237 10.6340668301457 1.63421434058126 0.103200299076188 -9.89009410805133 24.353419767528 -0.406106994519039 0.684936268714542 FAM229B other 1 1 1 1.63421434058126 -0.406106994519039 0.0728419308321357 -5.63635893478576 7.53331623794312 -0.748190937000236 0.454894513204643 -34.8822259694623 15.2591036095266 -2.28599443729345 0.022907872656619 FANK1 other 1 1 1 -0.748190937000236 -2.28599443729345 0.86053482124665 0.904971265341175 23.4431093361767 0.0386028684319896 0.969231086771795 -46.1152218044687 84.1895317363381 -0.547754820027872 0.584242120637655 LOR other 1 1 1 0.0386028684319896 -0.547754820027872 0.452049474400851 13.7195327517378 72.8748983221299 0.188261432504416 0.850791796463871 -327.820138991573 261.700506915082 -1.25265381735751 0.211252109694533 PRR9 other 1 1 1 0.188261432504416 -1.25265381735751 0.591524145445071 -1862.3964890614 1919.66731042484 -0.970166277743844 0.332696331865779 2471.53461185603 6974.71045820401 0.354356589662999 0.723305055835777 SPRR2E other 1 1 1 -0.970166277743844 0.354356589662999 0.297099711528126 -87.7987794412129 64.5637258521326 -1.35987783050648 0.17482890775589 -196.410759491047 261.659215639411 -0.750635742032178 0.453425227398055 KPRP other 1 1 1 -1.35987783050648 -0.750635742032178 0.00186374771098811 10.5752957075956 10.9576729828346 0.965104153424 0.335221423428291 -60.3767663858959 22.1953070975866 -2.72024920044746 0.00687976149484675 EEF1AKMT2 other 1 1 1 0.965104153424 -2.72024920044746 0.28323770623171 -0.783293127432164 3.08343159777468 -0.254032918387899 0.799633276965653 -11.1104559166203 7.00530994558655 -1.58600490241265 0.113725840103789 DDO other 1 1 1 -0.254032918387899 -1.58600490241265 0.2960756765307 -11.5857671123683 9.65364307954371 -1.20014454821919 0.23097093990197 -27.8989980965986 21.8131333958756 -1.27900002215517 0.201823752468166 CCDC162P other 1 1 1 -1.20014454821919 -1.27900002215517 0.876273315069378 0.944154460441824 22.6658179200915 0.0416554330300563 0.966799689192346 -46.3548467143404 90.3105128135003 -0.513282953116073 0.608112069038798 ADAMTSL4-AS1 other 1 1 1 0.0416554330300563 -0.513282953116073 0.156213540925246 24.0255946554158 16.4347858911832 1.46187451509818 0.14475691636356 57.0404473924403 32.2561851213089 1.76835689583015 0.0779539794425977 PLPP4 other 1 1 1 1.46187451509818 1.76835689583015 0.0428050091182393 3.41341028399485 1.35290929107934 2.5230148883608 0.0121288962026525 -0.197348518551466 5.60259132660397 -0.0352245072051489 0.971923102007925 HIST2H3C other 1 1 1 2.5230148883608 -0.0352245072051489 0.0630515254000971 103.183947941017 44.3752247178658 2.32526029100815 0.0206950149597986 -84.4160334549338 183.764167161623 -0.459371567149372 0.64628522314721 HIST2H2AA3 other 1 1 1 2.32526029100815 -0.459371567149372 0.00476300006979059 12.0064525918211 3.69797724754405 3.24676215890592 0.00129380938417093 7.61045230424019 15.0919771682626 0.504271389983577 0.614425462938284 HIST2H2BF other 1 1 1 3.24676215890592 0.504271389983577 0.383728590559892 49.6886951040132 55.3082871366834 0.898395117194961 0.369650409514025 -61.2238012556092 106.685503155237 -0.573871795557109 0.566457684170449 PNLIPRP3 other 1 1 1 0.898395117194961 -0.573871795557109 0.0679537677809239 3.12299864918425 1.34093376071234 2.32897309373823 0.0204947270016381 -0.222324050182373 5.55299893854952 -0.0400367535889437 0.968089268505542 HIST2H3A other 1 1 1 2.32897309373823 -0.0400367535889437 2.3340688125693e-08 235.181291569341 163.757264463232 1.43615791543798 0.151937322034801 -1400.62111142828 300.970330105627 -4.65368500256062 4.78699411614378e-06 ATP1A1-AS1 other 0.000266317251514157 0.0710102707188768 1 1.43615791543798 -4.65368500256062 0.71276060037682 1.47113461478041 7.5904193364304 0.193814669463604 0.846443970415615 -9.18946105223469 14.3242963781885 -0.6415296646771 0.521637848708727 RBM20 other 1 1 1 0.193814669463604 -0.6415296646771 0.438097455704083 155.89294787144 128.32562722611 1.21482319035742 0.225334790210994 -24.9714095706789 285.373444341706 -0.0875043213228282 0.930325726409898 SNHG5 other 1 1 1 1.21482319035742 -0.0875043213228282 0.000120097793630969 112.352592942891 26.0877545525729 4.30671764856091 2.21819386766361e-05 85.9757083790685 121.661093532241 0.706682028600084 0.480288163862887 PCMTD2 other 1 1 0.243047502079902 4.30671764856091 0.706682028600084 0.65778895964843 7.54962133265446 10.2942195971528 0.733384523363242 0.463867656654436 -17.6713927699736 47.1941639285625 -0.374440212495823 0.708327972575366 SOX18 other 1 1 1 0.733384523363242 -0.374440212495823 0.193413780768049 -21.0840986154281 16.0001079846218 -1.31774726993672 0.188536795275676 -110.058039124884 72.2862408025424 -1.52253095337353 0.128869861541818 LIME1 other 1 1 1 -1.31774726993672 -1.52253095337353 0.00860147555667208 -9.91161648294047 6.12429088761353 -1.61841046822039 0.106559341892634 -42.6728662334128 14.3263113642759 -2.9786359620678 0.0031166813654524 EFCAB7 other 1 1 1 -1.61841046822039 -2.9786359620678 0.559935451529346 -15.9545855592284 17.7988173928461 -0.896384585958005 0.370725460564095 -33.8596508777509 43.067071365242 -0.786207415651623 0.432331438098957 LDLRAD1 other 1 1 1 -0.896384585958005 -0.786207415651623 3.67812204943591e-12 65.4586586777816 9.3570816435688 6.995627608184 1.59096161221948e-11 -39.6695240245456 19.7465606649244 -2.00893333769308 0.0453971375658645 ARRDC1-AS1 other 4.78266210088152e-08 1 2.19266329396089e-07 6.995627608184 -2.00893333769308 0.15429193328098 -10.0284427520211 8.91957097462952 -1.12431895889899 0.261725705509844 -38.7059267160231 21.5823215235698 -1.79340886353457 0.0738576513022435 ZYG11A other 1 1 1 -1.12431895889899 -1.79340886353457 0.000271932338027526 4.72671498677569 1.15155923135713 4.10462167995057 5.14518499243863e-05 5.08280776762658 5.31614832935932 0.956107213855551 0.339739806486515 LINC01270 other 1 1 0.548322364644185 4.10462167995057 0.956107213855551 0.0131628942629904 8.83325565636534 3.44355544534743 2.56515563537678 0.0107713421055918 -1.89401233224069 6.91819774295758 -0.273772505876796 0.784437189527593 LIPN other 1 1 1 2.56515563537678 -0.273772505876796 0.000516532401110866 26.1962764114467 7.64924499271064 3.42468785303784 0.000696210329239592 -5.09560169499323 15.3675438899638 -0.331582049251284 0.740423292169177 LIPK other 1 1 1 3.42468785303784 -0.331582049251284 0.369407888645995 241.378755087563 189.030569204241 1.27692973736307 0.202552846900501 -242.779919793882 859.376043526302 -0.282507199988583 0.777737266409647 SLC12A5-AS1 other 1 1 1 1.27692973736307 -0.282507199988583 0.298187091577138 3.32840311513999 2.6203503821201 1.27021299817432 0.204940286187224 -3.53094293083588 7.23717401700588 -0.487889737422215 0.625965213281079 LRRC73 other 1 1 1 1.27021299817432 -0.487889737422215 0.608154365707903 4.24437122926165 4.41631159599598 0.96106697568844 0.337244116792016 5.92279415262513 13.7433961257803 0.430955645782121 0.666790768359083 FOXO6 other 1 1 1 0.96106697568844 0.430955645782121 2.2389710932968e-19 133.659909287944 14.7081136956621 9.08749497410838 1.08425887839645e-17 -107.685729587695 67.0065555826325 -1.60709245015433 0.109020316342862 SYS1 essential 3.23173087606461e-15 1 1.58941508984136e-13 9.08749497410838 -1.60709245015433 0.0162423455631316 15.8014364155346 16.3426736012957 0.966881968093754 0.334337792236605 -97.2575616903883 39.0164058855688 -2.492735029865 0.0131847779165308 INPP5B other 1 1 1 0.966881968093754 -2.492735029865 0.263859734084993 8.21575098844236 5.07396810954328 1.6191964180835 0.106399421332798 4.7925312148244 9.19038095262691 0.521472530848086 0.602401761170182 NEU4 other 1 1 1 1.6191964180835 0.521472530848086 0.0023290470703906 350.686648296893 138.680560773501 2.52873687805207 0.0119322471131357 -1166.70126073738 645.579576943877 -1.80721525649937 0.0716766667506533 MAFB other 1 1 1 2.52873687805207 -1.80721525649937 0.0214687819718847 27.9730371686181 23.3373102637535 1.19864015400543 0.231560379048755 -72.7559900427371 42.239794467062 -1.72245132725424 0.0859600588611064 TRAF3IP1 other 1 1 1 1.19864015400543 -1.72245132725424 4.61092283453865e-09 172.717630679661 60.8253398614223 2.83956704677955 0.00480746840302788 -399.920120870776 104.975163868174 -3.8096641732609 0.000166930760157793 GIGYF2 other 5.43904457562179e-05 1 1 2.83956704677955 -3.8096641732609 0.563301993949436 3.0340491059024 5.38632938529108 0.563286960167669 0.573633970787128 10.0295008485432 9.38171409730515 1.06904780347379 0.285853876701309 C2orf72 other 1 1 1 0.563286960167669 1.06904780347379 3.850339731387e-05 36.0281072969062 14.9079195433848 2.41670926597489 0.016220594860586 -82.2254103239664 31.2006407449661 -2.63537569616203 0.00881366147057271 RUFY2 other 0.347839691333502 1 1 2.41670926597489 -2.63537569616203 0.0569240921995576 18.6118920775573 10.2760511804567 1.8111910646138 0.071048824066902 -27.6046643394026 20.4960130522591 -1.3468309309239 0.1789877479555 GGTA1P other 1 1 1 1.8111910646138 -1.3468309309239 3.23483227728995e-05 27.5447650851236 56.4854958841293 0.487643148988674 0.626137588315167 -492.205873227338 113.184734769898 -4.34869485030804 1.84478718573157e-05 PHACTR4 other 0.294402085556158 0.269763230169528 1 0.487643148988674 -4.34869485030804 2.90866517891324e-08 32.9206670966551 8.24442560966463 3.99308195079879 8.10024730887213e-05 -46.6781586248553 17.4696800856942 -2.67195268578958 0.00792840415081791 TIMM23B other 0.00033022075776202 1 0.847447873454203 3.99308195079879 -2.67195268578958 0.0856060137645094 85.5470266876919 52.3343153757498 1.63462588692489 0.103110810164426 -104.499744132653 102.657696121552 -1.01794359391155 0.309473756337292 ZDHHC18 other 1 1 1 1.63462588692489 -1.01794359391155 0.0535868810430657 -12.5722361610224 6.29256780893595 -1.99795004881295 0.0465681205509136 -27.3990314351009 13.26464617937 -2.0655682077456 0.0396740651734009 C10orf128 other 1 1 1 -1.99795004881295 -2.0655682077456 0.233577623036779 3.27149037317171 5.86939273490077 0.557381405697845 0.577656533416376 -15.4706376327673 12.2692519267118 -1.26092753862895 0.208253491888083 AGAP9 other 1 1 1 0.557381405697845 -1.26092753862895 0.292901039773195 4.55819272168944 8.5770382467392 0.531441342636238 0.595481679045496 -21.1885961880109 18.5190843680841 -1.14414923366986 0.253416869936616 GPRIN2 other 1 1 1 0.531441342636238 -1.14414923366986 5.94654889220244e-08 61.1952326775613 29.4073187207702 2.08095247508368 0.0382357088810422 -275.843994279022 57.6828430632199 -4.78208041820511 2.65446013748086e-06 TMEM57 other 0.000663932183814402 0.0395328748275024 1 2.08095247508368 -4.78208041820511 0.461543061076455 1.17059335211047 6.06080438482176 0.193141582830493 0.846970999596259 -13.8799512747661 13.1231728253268 -1.05766733849444 0.291007394885337 PTPN20 other 1 1 1 0.193141582830493 -1.05766733849444 0.144993005164164 30.7144311213066 16.212612085534 1.89447764242211 0.0590744743066227 7.44979616551926 30.5501437190268 0.243854701111585 0.807501594042899 ZDBF2 other 1 1 1 1.89447764242211 0.243854701111585 0.00102135454513401 7.37314332092356 2.70449892108869 2.72625116003208 0.00675984480892467 -8.56802732862191 6.26158838502293 -1.36834726299093 0.172166357269101 GGNBP1 other 1 1 1 2.72625116003208 -1.36834726299093 2.73969144222005e-22 426.102773100579 43.4652490569853 9.80329763075638 5.26632802412221e-20 -48.9488436823478 100.17160534509 -0.488649887497758 0.625425342058861 DAXX other 4.03446961781325e-18 1 7.82207701422871e-16 9.80329763075638 -0.488649887497758 1.26804548710445e-07 346.61616365123 75.9858957802867 4.56158554284168 7.27341208122193e-06 -302.278640871191 167.649683451653 -1.8030373493569 0.0723348787586503 BMPR2 ts 0.00139091909480488 1 0.0824441259406506 4.56158554284168 -1.8030373493569 0.0457201227229603 38.8999867791803 82.7187600574065 0.470268011176472 0.6384838936313 -352.749424438456 159.806123380097 -2.20735862291989 0.0279983447808941 TCEA3 other 1 1 1 0.470268011176472 -2.20735862291989 6.88603389863829e-21 328.581923036411 36.7474326208389 8.94162937658066 3.13315253242126e-17 -126.669912317941 84.3049263031357 -1.50252088309137 0.133948805601232 RING1 other 1.00542980954018e-16 1 4.58160894815961e-13 8.94162937658066 -1.50252088309137 6.99394145987032e-07 89.6975527544679 18.6292244460224 4.81488389462287 2.27560318425222e-06 -22.836752412294 42.7386427294479 -0.534334994137727 0.593480811408865 HSD17B8 other 0.00731636216117034 1 0.02659725001754 4.81488389462287 -0.534334994137727 2.41284788864179e-15 230.454539868685 30.0335212827177 7.67324409613255 2.04278004369537e-13 -55.8529242780672 68.9020597571579 -0.810613274478561 0.418190234023343 RXRB other 3.33576220604727e-11 1 2.89318937588575e-09 7.67324409613255 -0.810613274478561 0.000433915635790967 83.8643784786642 21.13992340917 3.96710890836463 8.98283964820117e-05 63.9333068292252 48.7582509944139 1.31123052048257 0.190719982590553 OXLD1 other 1 1 0.935832234549598 3.96710890836463 1.31123052048257 0.679531468425513 5.18150258066782 6.18868963697411 0.837253584298541 0.4030748913578 0.946141925558013 14.1979176924108 0.0666394851735021 0.946910326069079 COL11A2 other 1 1 1 0.837253584298541 0.0666394851735021 0.748080262546922 38.6073303254802 65.5080628325801 0.589352343148194 0.556040780808315 100.719802835064 150.286755168579 0.67018416042109 0.503223743468074 HLA-DOA other 1 1 1 0.589352343148194 0.67018416042109 2.19963829731063e-06 876.044727186548 183.457462103349 4.77519266397044 2.73719436081531e-06 -53.0304581044461 420.882949346845 -0.125998114646227 0.8998125422292 BRD2 other 0.0221525572922154 1 0.0318499935824469 4.77519266397044 -0.125998114646227 0.775808464646102 1.60294582353144 106.111474969018 0.0151062439194202 0.987956833420875 162.027375507116 243.437961217109 0.665579742358312 0.50615921724634 HLA-DMA other 1 1 1 0.0151062439194202 0.665579742358312 0.577083197227672 64.0838717039431 158.221533003712 0.405026234339669 0.685728851414043 -269.887419364105 362.987390631552 -0.743517340628652 0.457714069996508 PSMB8-AS1 other 1 1 1 0.405026234339669 -0.743517340628652 0.0787491407814493 1889.42535388273 893.186959442132 2.11537498830349 0.0351877283401371 -900.841055515045 2331.79470192581 -0.386329488943022 0.699515147328616 COL5A2 other 1 1 1 2.11537498830349 -0.386329488943022 0.140944107118896 202.521777676346 152.58274630041 1.32729147027944 0.185358463340604 -303.224399998723 350.051044782145 -0.866229095780688 0.387013543227746 PSMB8 other 1 1 1 1.32729147027944 -0.866229095780688 0.0339040875878999 466.237092272042 239.98812958476 1.94275063970351 0.0529231834125409 -488.730431930697 550.574016612994 -0.887674349285961 0.37538264293946 TAP2 other 1 1 1 1.94275063970351 -0.887674349285961 0.116976417192607 -36.7535919300045 21.9686988866586 -1.6729981197168 0.0953049384246683 -79.7947759295626 51.7825356953196 -1.54095922221852 0.124314970442377 TNRC6C-AS1 other 1 1 1 -1.6729981197168 -1.54095922221852 0.597786513790648 -867.643518397109 1105.63933327512 -0.784743715499863 0.433184404629145 757.103815554509 2544.40164475477 0.297556723057173 0.766234588399571 HLA-DRA other 1 1 1 -0.784743715499863 0.297556723057173 0.538438630000907 -102.064325039535 113.067348766114 -0.90268610835354 0.367371480260341 115.333497526976 215.055309066144 0.536296909050049 0.592125971559658 COL15A1 other 1 1 1 -0.90268610835354 0.536296909050049 0.241568046099534 -2.44898164709796 2.24502050134822 -1.09085046021952 0.276159377024638 4.00715861299485 5.16604115543628 0.775672994547881 0.438514953306783 C6orf10 other 1 1 1 -1.09085046021952 0.775672994547881 0.379258778096795 -12.395510183529 25.2520545315176 -0.490871353380687 0.623853890647293 -80.9964352224934 58.1077780317814 -1.39390005892487 0.164314968290735 NOTCH4 other 1 1 1 -0.490871353380687 -1.39390005892487 1.03602461695186e-25 396.306352818976 37.4543171055895 10.5810593663136 1.23499693004291e-22 -69.223051308293 86.2888641622644 -0.802224620527168 0.423018394620838 PBX2 other 1.54896040480472e-21 1 1.8507663993623e-18 10.5810593663136 -0.802224620527168 0.202841997998862 8.27510043227882 4.90403380886248 1.68740688886039 0.0924995608170374 0.875441061909061 11.2981236845708 0.0774855264776929 0.938285730519722 AGER other 1 1 1 1.68740688886039 0.0774855264776929 0.00175153427849739 91.8907464829605 28.3612556184752 3.24000981194573 0.00132091586938587 -15.4132616432708 65.3398786215928 -0.235893637521653 0.813666110533064 RNF5 other 1 1 1 3.24000981194573 -0.235893637521653 1.58883370861928e-07 60.0009962007386 12.3334217865658 4.86491074732356 1.80234976115861e-06 -26.4282319300978 27.4885374487569 -0.961427357834673 0.337065513412002 FKBPL other 0.0017335764594745 1 0.0211685979448079 4.86491074732356 -0.961427357834673 0.000360458094991613 209.119704434975 52.2134596383256 4.00509190318961 7.72342834707297e-05 22.3289528276901 128.546014593829 0.17370396817236 0.862208640040514 MRPL38 other 1 1 0.809993164922077 4.00509190318961 0.17370396817236 0.170323682720828 14.6976647561576 12.5945883288014 1.16698254618985 0.244091759242258 -39.8473486358546 31.0385743641411 -1.28380086560581 0.200146272134963 SMIM5 other 1 1 1 1.16698254618985 -1.28380086560581 0.110880784462781 -10.605306145973 5.04157032520381 -2.1035719948118 0.0362009362033775 -3.46369621405465 15.5946574254854 -0.22210787448233 0.824372481845607 SP5 other 1 1 1 -2.1035719948118 -0.22210787448233 1.48735885003288e-08 75.1168739946816 13.6648942924896 5.49706952625068 8.02095152731184e-08 -16.373320145645 31.6879119223431 -0.516705555915793 0.605726602601772 STK19 other 0.000171195003638784 1 0.00100213768382234 5.49706952625068 -0.516705555915793 2.9131518521047e-06 44.8989268202424 9.45409693182319 4.74915025136979 3.09160565624775e-06 -0.528812569611933 21.7557665566047 -0.0243067771588767 0.980623104904426 DXO other 0.0290849080914133 1 0.0358533507955052 4.74915025136979 -0.0243067771588767 1.78114014778167e-25 349.138403182533 35.9598867136439 9.70910742747316 1.07653439146599e-19 -191.82380483796 82.7508863496618 -2.31808761573156 0.0210766932575258 SKIV2L other 2.66031092472671e-21 1 1.59553162159175e-15 9.70910742747316 -2.31808761573156 0.000842446841633081 21.4738267242775 7.17647261721087 2.99225369755863 0.00298460622569203 -26.2875927062857 13.695907441465 -1.9193757564905 0.0558258663459012 C9orf129 other 1 1 1 2.99225369755863 -1.9193757564905 0.00128710165930051 25.746152897277 7.43997404945382 3.46051649187769 0.000612526431592843 2.58770288828573 17.1208672572706 0.151143213097855 0.879958277902246 ZBTB12 other 1 1 1 3.46051649187769 0.151143213097855 9.0931032885368e-16 221.472309122165 59.7572231728711 3.70620148264704 0.00024809563171556 -407.509288000925 109.58123358429 -3.71878719258503 0.000236548268240764 SDHD ts 1.26412321917239e-11 1 1 3.70620148264704 -3.71878719258503 1.27130788421886e-13 419.169041231073 57.3045150775686 7.31476465098217 2.10011845742687e-12 -48.3173870259637 131.869142199137 -0.366404044344197 0.714306496177234 EHMT2 other 1.70495100352591e-09 1 2.93617561532851e-08 7.31476465098217 -0.366404044344197 0.00349892474046416 14.4879630796746 5.55867979133607 2.6063676310796 0.00957890556275673 -24.7303220596271 14.592504548164 -1.69472772669025 0.0910999352589231 PKP4-AS1 other 1 1 1 2.6063676310796 -1.69472772669025 0.0106352449621424 30.7017720591603 45.4396181079001 0.67566087343112 0.499748566937946 -153.707707159973 82.8616964329619 -1.85499107279717 0.0645257882744624 LAYN other 1 1 1 0.67566087343112 -1.85499107279717 0.425757744695815 -73.3291786875806 71.2250795879826 -1.02954154788973 0.304002800518079 -189.149874879951 166.426428664079 -1.13653748625309 0.25658207931681 SLC44A4 other 1 1 1 -1.02954154788973 -1.13653748625309 1.08369256528383e-11 317.458879005115 48.0411983993091 6.6080549524693 1.62710049165339e-10 -65.3029472188551 112.254350919511 -0.581740900766321 0.561150796219694 NEU1 other 1.39243657713319e-07 1 2.2016296752562e-06 6.6080549524693 -0.581740900766321 0.00440780572541748 219.732924886632 66.36561564774 3.31094532525617 0.00103606042422973 155.145470923408 155.071675064999 1.00047588225495 0.317836190259094 C6orf48 other 1 1 1 3.31094532525617 1.00047588225495 0.0158041954253113 3912.67225680421 1371.45125298104 2.85294300347859 0.00461367562023803 4975.70462727877 3204.56973078655 1.55269039068702 0.121485535868777 HSPA1B other 1 1 1 2.85294300347859 1.55269039068702 0.0203951216994097 3668.10165227682 1339.08588389165 2.73925794932329 0.00650300222845874 5013.65231238963 3128.94394249539 1.60234648000474 0.110065620582769 HSPA1A other 1 1 1 2.73925794932329 1.60234648000474 0.000117336555323593 14.2148432850959 3.29560535401181 4.31327229997118 2.14558833660457e-05 13.5019510652268 7.7005997399678 1.75336357182009 0.08049706688402 HSPA1L other 1 1 0.235263761108691 4.31327229997118 1.75336357182009 2.41322184303723e-07 174.364982537029 38.9224941065879 4.47979983141718 1.04125223712909e-05 -136.806196110175 90.9473422329605 -1.50423522833408 0.133507121758822 LSM2 essential 0.00260676223484881 1 0.11663066308083 4.47979983141718 -1.50423522833408 5.66766171573475e-19 769.210206873478 97.1092051361813 7.92108436882759 3.92462821399369e-14 -535.100173908697 226.907969702697 -2.35822555994752 0.0189636877585878 VARS essential 8.15633197511387e-15 1 5.60986356908258e-10 7.92108436882759 -2.35822555994752 0.00981060605633268 17.2487992224579 6.59987123995311 2.61350541477844 0.00938528028585721 -7.60689520583042 15.4214359108065 -0.493267634079387 0.622161831120652 VWA7 other 1 1 1 2.61350541477844 -0.493267634079387 0.0108438449577237 -3.36539724806906 12.0680974422347 -0.278867258420634 0.780529683676182 -61.9196524976028 24.3057920408467 -2.54752663042393 0.0113238746289872 CARD16 other 1 1 1 -0.278867258420634 -2.54752663042393 0.00110424999135375 18.8406192084111 10.2610203440256 1.83613506032867 0.0672770358373928 -78.4540115930358 26.9980529412392 -2.90591368806446 0.0039203769078289 MBD5 other 1 1 1 1.83613506032867 -2.90591368806446 0.00013459718787356 35.4265181440894 8.28420190381544 4.27639482419823 2.51064297607263e-05 27.4494765915434 19.3570880532479 1.41805815606328 0.157146848866438 MSH5 other 1 1 0.274036680838328 4.27639482419823 1.41805815606328 0.00217907516572765 7.14990275917826 2.22660027343889 3.2111299205652 0.00145645626220515 -0.814849245482366 5.20273383637497 -0.156619437224587 0.875643547317883 MPIG6B other 1 1 1 3.2111299205652 -0.156619437224587 0.0693256697964775 126.17355741823 82.5374169401189 1.52868313664055 0.127330869210915 -200.414408369152 192.85913911172 -1.0391750647246 0.299507867067372 LY6G6C other 1 1 1 1.52868313664055 -1.0391750647246 9.60189101598033e-07 176.297286774383 35.6537067121559 4.94471130863584 1.23330568588756e-06 -8.13197257068589 83.3094060556414 -0.0976116978346315 0.92230174500681 ABHD16A other 0.0099581211726732 1 0.0146405717971713 4.94471130863584 -0.0976116978346315 0.274645780738801 1.97482428876727 1.63199510843342 1.21006752934629 0.227146082764987 5.49669727293091 3.81336348186613 1.44143019648392 0.15044103874718 LY6G5C other 1 1 1 1.21006752934629 1.44143019648392 3.93815914176678e-15 661.2970224024 93.0094697139033 7.10999669642829 7.61281679336114e-12 -385.348814315696 217.328418107328 -1.77311746743305 0.0771604005593984 CSNK2B essential 5.42166369047033e-11 1 1.05521253572779e-07 7.10999669642829 -1.77311746743305 4.4381583823902e-11 98.8855848052442 16.833325597065 5.87439387630484 1.06387179026645e-08 -62.5424615050362 39.3331994553761 -1.59006799271417 0.112806905142073 GPANK1 other 5.61693324875304e-07 1 0.000137399041712913 5.87439387630484 -1.59006799271417 1.65679250815211e-19 206.058784215743 22.573461389286 9.1283645278054 8.03987762904442e-18 -13.5174221136108 52.7457544917819 -0.256275073583731 0.797903115801386 C6orf47 other 2.39489357053388e-15 1 1.1796108457334e-13 9.1283645278054 -0.256275073583731 0.854753284261208 -0.468227240103794 1.8069220249139 -0.259129743092321 0.795703859046507 1.80481741036883 4.29228444040701 0.420479452241913 0.674421028761604 FAM155A other 1 1 1 -0.259129743092321 0.420479452241913 1.73218054826281e-06 16.6421393557591 3.43470571757915 4.84528827916263 1.97377893515547e-06 -0.52977837937092 8.02562537515563 -0.0660108533113093 0.947410405436394 APOM other 0.0175972221898019 1 0.0231366366778925 4.84528827916263 -0.0660108533113093 5.77533462782635e-24 1150.89298433668 115.043584388973 10.0039736283373 1.11498292655284e-20 -278.647803645642 268.813920620761 -1.03658249171833 0.300713140271529 BAG6 other 8.56828645384318e-20 1 1.65987508275922e-16 10.0039736283373 -1.03658249171833 2.85029411602685e-14 1990.94648784225 255.972078402452 7.77798305294839 1.02156272277794e-13 152.910731675897 598.111214373843 0.255656018481409 0.798380710986939 PRRC2A other 3.86813414486003e-10 1 1.45399022332985e-09 7.77798305294839 0.255656018481409 0.124410940388972 -50.1376132112928 24.8226958180592 -2.01982949711756 0.0442341583730872 -25.931993912715 58.0013759017463 -0.447092737190295 0.655110559085775 AIF1 other 1 1 1 -2.01982949711756 -0.447092737190295 0.0750813277230507 -27.8417457779794 12.8929800761818 -2.15944999631339 0.0315579026022258 -3.7277670373322 30.1260825727193 -0.123738857461271 0.901599729500367 LST1 other 1 1 1 -2.15944999631339 -0.123738857461271 0.000402907487194616 89.2437582736412 30.7112272727629 2.90590009578646 0.00391725574764364 -104.223736566298 71.7606762177515 -1.4523795212024 0.147375900740446 NFKBIL1 other 1 1 1 2.90590009578646 -1.4523795212024 9.42328523437969e-06 54.340401808313 12.8704442772742 4.22210769400275 3.16030647032234e-05 -41.1271167965486 33.8319566614351 -1.21562927051835 0.225025038697887 ZNF814 other 0.0901242999816073 1 0.342450809124129 4.22210769400275 -1.21562927051835 0.0127250151957294 44.7741972945613 17.5630907904331 2.54933472865439 0.0112590706673135 -18.7637543128684 41.0383883522953 -0.457224444385837 0.647819976733219 MICB other 1 1 1 2.54933472865439 -0.457224444385837 0.00109878019324213 27.6295070734417 8.77246803736921 3.14957056050187 0.0017893947273277 -22.1764189360451 22.7980033019769 -0.972735140104225 0.331419662901228 ZNF551 other 1 1 1 3.14957056050187 -0.972735140104225 0.000257311242702566 65.076397542398 17.5400984352162 3.71015007599618 0.000244170923978131 -10.4983517608617 40.9846637992662 -0.256153175057877 0.797997153364308 MICA other 1 1 1 3.71015007599618 -0.256153175057877 6.58992540388525e-06 11.7106515942016 2.96007853485516 3.95619624827778 9.39477161983544e-05 -11.9325079166213 7.39809938089281 -1.61291533166473 0.107754811764078 ZNF805 other 0.0639222764176869 1 0.976492562165696 3.95619624827778 -1.61291533166473 0.539162629480243 2160.388893819 2149.62696549475 1.00500641669322 0.315653098744167 -261.105664473148 5033.6178889168 -0.0518723650136534 0.958662759339575 HLA-C other 1 1 1 1.00500641669322 -0.0518723650136534 0.232948524535194 7.44860697740036 4.75956928019705 1.56497500906048 0.118577110033636 -0.367173634055116 11.1451212033082 -0.0329447860958324 0.973739157139214 POU5F1 og 1 1 1 1.56497500906048 -0.0329447860958324 0.00413550057692013 139.348412655071 42.7439891101834 3.26007037611452 0.00123375408779981 58.3386578561741 100.090346689136 0.582859983864024 0.560398059395766 CCHCR1 other 1 1 1 3.26007037611452 0.582859983864024 0.141623197884775 35.4874828204497 31.5969974448644 1.12312832516362 0.262224908338414 -79.4311589256297 73.9882845384395 -1.07356400301946 0.283827018847116 PSORS1C2 other 1 1 1 1.12312832516362 -1.07356400301946 0.298866315644402 709.458322454584 561.45394489784 1.26360911505159 0.207290138390814 -475.90472320248 1316.31538963341 -0.361543082266188 0.717932104383717 CDSN other 1 1 1 1.26360911505159 -0.361543082266188 0.249865030313236 725.778166498283 553.224704796662 1.31190483759225 0.190492597288072 -576.087647562098 1295.44419350651 -0.444702790324564 0.656835178225529 PSORS1C1 other 1 1 1 1.31190483759225 -0.444702790324564 0.76651278285394 25.1788256002965 60.8556764274706 0.413746540642027 0.679336893333982 -56.8714231243056 142.674682680529 -0.398609073844234 0.690447116285099 C6orf15 other 1 1 1 0.413746540642027 -0.398609073844234 0.940278765018421 76.3000303201302 432.318851979586 0.176490176106716 0.860020509513363 -216.451762663822 1013.56124266421 -0.213555682234717 0.831029559719851 MUC21 other 1 1 1 0.176490176106716 -0.213555682234717 5.55583893929847e-21 282.985270375504 30.2774655882741 9.34639887709421 1.63246850144316e-18 -52.7720386184825 70.553314342017 -0.747973913212109 0.455026945516614 DHX16 essential 8.11763627420899e-17 1 2.40642181797736e-14 9.34639887709421 -0.747973913212109 3.14186685537809e-05 54.671551216547 12.1710654099911 4.49192814062669 9.87993896433807e-06 18.3404409875025 28.3613237457005 0.646670837791301 0.518310001203732 C6orf136 other 0.28644400120482 1 0.110931954691588 4.49192814062669 0.646670837791301 1.33318315473934e-12 339.96598225987 49.0503835493104 6.93095461563725 2.32211058398653e-11 -64.5053839424049 114.298441494761 -0.564359260711017 0.572906246314366 MRPS18B essential 1.75193598364296e-08 1 3.19104436451428e-07 6.93095461563725 -0.564359260711017 0.433137261729147 52.9035024406918 57.6157622621518 0.918212314886694 0.35920144320825 -67.5613960146537 134.257703112073 -0.503221747792424 0.615155656229178 PPP1R10 essential 1 1 1 0.918212314886694 -0.503221747792424 5.07904291378822e-26 722.559165416243 72.0757558971114 10.0249960118032 9.65090761622858e-21 -355.477121684967 167.952745166913 -2.11653058324048 0.03507377499775 ABCF1 essential 7.59875610331856e-22 1 1.43740618036108e-16 10.0249960118032 -2.11653058324048 1.11690185238966e-05 57.0945412068602 11.9518764182737 4.77703577319172 2.71732947706108e-06 26.4498556283992 27.8505640261376 0.949706282557732 0.342980457575558 PRR3 other 0.106094506958494 1 0.031632432442468 4.77703577319172 0.949706282557732 0.0144679801387301 26.2143663605016 9.9958612878594 2.62252202242348 0.00914702841641592 -28.9827896615911 32.5127152397245 -0.891429382255332 0.373370733403849 LINC01123 other 1 1 1 2.62252202242348 -0.891429382255332 1.12327449004983e-13 500.621616744855 69.0602892245176 7.24905184102712 3.18907387033002e-12 -101.592934106158 160.926028633486 -0.631302064487893 0.528295121599616 GNL1 other 1.5079960028919e-09 1 4.44525006785302e-08 7.24905184102712 -0.631302064487893 0.0415007931756454 2143.52268799026 951.875746516293 2.25189337561672 0.025008889103416 -525.054782132421 2218.08488437404 -0.236715369114737 0.813029542562937 HLA-E other 1 1 1 2.25189337561672 -0.236715369114737 0.696971567363508 13.2199749126354 15.5495678082336 0.850182788079508 0.395865138601505 8.476508196112 50.3507452190744 0.168349210309222 0.866415921307951 ZNF468 other 1 1 1 0.850182788079508 0.168349210309222 0.0126981047692718 21.6581844125841 8.07052845024598 2.68361415811923 0.007665537216925 -13.2483804195247 20.1070959561769 -0.658890793996276 0.510444202091124 ZNF616 other 1 1 1 2.68361415811923 -0.658890793996276 0.753734232919937 10.5194016676362 14.1255984159247 0.744704851284527 0.456996718427821 5.92610782602412 31.8878635322562 0.185842109491894 0.852686327103851 TRIM31 other 1 1 1 0.744704851284527 0.185842109491894 0.0174185979156715 65.8598564814331 34.545172103786 1.90648511703941 0.0574828396701252 -97.3141370558926 77.98407552787 -1.24787190714487 0.21299031737327 RNF39 other 1 1 1 1.90648511703941 -1.24787190714487 4.85593178901424e-20 316.677986326647 36.7522956395042 8.61654981862566 3.21633683074503e-16 -134.945457565313 82.9665514579847 -1.62650435861072 0.104826703858414 PPP1R11 essential 7.05081295764868e-16 1 4.6736590487556e-12 8.61654981862566 -1.62650435861072 0.87516803268084 -84.9277108315463 178.777458792628 -0.475047085941958 0.635077476413217 -148.829729401281 403.581571609452 -0.368772361948439 0.712541268701856 HLA-J other 1 1 1 -0.475047085941958 -0.368772361948439 0.597915709412434 -50.4379358079236 93.6867152173733 -0.538368067349749 0.590697240980951 -211.669636758752 211.49328344695 -1.00083384828553 0.317663339254538 ZNRD1ASP other 1 1 1 -0.538368067349749 -1.00083384828553 0.845430964746234 2.2774796410163 10.0325159944399 0.227009819100065 0.820561061089523 -9.1984961581713 21.1257578908649 -0.43541614959759 0.66355392747476 DISP3 other 1 1 1 0.227009819100065 -0.43541614959759 1.51399834695145e-15 4905.62809988396 991.563473767223 4.94736668873666 1.22487954197413e-06 -8122.18176623889 1588.74649325922 -5.11232081436524 5.523793860645e-07 RACK1 other 2.0987045085441e-11 0.00830226217254944 0.0145429948018589 4.94736668873666 -5.11232081436524 0.789350265780462 48.9181946584486 94.6617061230547 0.516768571600197 0.605674679572282 -46.5692674043984 213.50854951118 -0.218114298050439 0.827479082084262 HLA-G other 1 1 1 0.516768571600197 -0.218114298050439 0.398683762922884 35.2780365262972 37.9957972399434 0.928472070306 0.353864745614931 -96.3003472961833 119.982036701309 -0.802623042113544 0.422790206661692 TBC1D8 other 1 1 1 0.928472070306 -0.802623042113544 0.992063149414696 34.8224704673852 323.820189845433 0.107536440158369 0.914430807995052 74.99829574637 730.373261458627 0.102684886898229 0.918277386473643 HLA-F other 1 1 1 0.107536440158369 0.102684886898229 0.643493797186435 4.63181818181816 5.97967433175546 0.774593719464049 0.439151717977366 -2.55647382920109 13.4870967935301 -0.189549601989024 0.849782255728562 ZFP57 other 1 1 1 0.774593719464049 -0.189549601989024 0.0379772232676275 37.0786371138884 14.9271964726443 2.48396523632813 0.0135042236936712 -16.7423193752861 36.0895650112751 -0.46391025688604 0.643027456877589 LINC02210 other 1 1 1 2.48396523632813 -0.46391025688604 2.88352754844394e-07 179.586753731343 53.7429729246724 3.34158577314018 0.000931968122417985 -462.554104477611 125.688528266475 -3.68016167312375 0.000273560355876391 AKT1S1 other 0.00310008046733208 1 1 3.34158577314018 -3.68016167312375 0.362629398514681 -446.028660952122 321.347791953452 -1.3879935450645 0.166104612370505 -175.483662783841 727.155159148688 -0.24132904865763 0.809454659335723 GABBR1 other 1 1 1 -1.3879935450645 -0.24132904865763 0.00423216072713866 26.8288468858095 10.2043807799607 2.62914991750364 0.00897311456226438 -7.52507232495271 20.3058278973717 -0.370586826746756 0.711190481651549 CASC10 other 1 1 1 2.62914991750364 -0.370586826746756 0.608082969358164 7.02932689639866 7.21144566167051 0.974745872905923 0.330431908132031 -0.0114672612591729 31.1327288355819 -0.000368334601175944 0.999706343929555 SPDYC other 1 1 1 0.974745872905923 -0.000368334601175944 2.547885537529e-14 250.451376510354 38.8031891156092 6.45440187310806 4.02314110362372e-10 -206.071059919239 87.8841233602374 -2.34480418123479 0.0196479243888714 TRIM27 other 3.4620668683944e-10 1 5.40307850216666e-06 6.45440187310806 -2.34480418123479 0.00372177215179156 -2.06259916262118 10.4740057093566 -0.19692553354049 0.844011218026771 -51.0447698115947 15.849080270118 -3.22067709555583 0.00141070933638435 RANBP17 other 1 1 1 -0.19692553354049 -3.22067709555583 0.771373231473105 1.35841194104811 7.11585127722872 0.190899428350215 0.848725445565029 20.7731232244597 29.4453239453134 0.705481225577278 0.481024035916532 LINC01291 other 1 1 1 0.190899428350215 0.705481225577278 0.649651419558431 -5.85750428198871 8.70575605360174 -0.672831198798104 0.501540265266102 -15.6418798829035 22.4616095193794 -0.696382860249085 0.486694601501182 TTC25 other 1 1 1 -0.672831198798104 -0.696382860249085 0.227706561577693 50.3029397454205 37.8157657181885 1.33021079409813 0.184396072644022 -158.594979046662 156.481273769087 -1.01350772029561 0.311583408428316 MRPL53 essential 1 1 1 1.33021079409813 -1.01350772029561 0.0147067337089245 54.4329895182408 31.6828225687901 1.71805998029548 0.0867560279876319 -334.814994138293 155.823903209148 -2.14867544223239 0.032412489096339 MROH6 other 1 1 1 1.71805998029548 -2.14867544223239 0.000346160136100173 69.2805508445044 20.6388301495194 3.35680609523877 0.000883504945767851 -100.472836272255 57.8804409849131 -1.7358685345615 0.0835496453252166 ATXN2 other 1 1 1 3.35680609523877 -1.7358685345615 1.18652147778817e-12 1067.68036193555 137.98312187848 7.73776058550006 1.33400035638351e-13 154.788829595215 570.97282734102 0.271096665520942 0.78649147538734 DCTN1 essential 1.56027574329144e-08 1 1.8940137059933e-09 7.73776058550006 0.271096665520942 0.437789042574325 28.1874985479636 22.1899018311664 1.27028495945725 0.204905967923885 -1.13061163642556 62.230334476092 -0.0181681754717215 0.985516013248283 TCTN1 other 1 1 1 1.27028495945725 -0.0181681754717215 0.532038083902322 10.8483202843668 9.75151586577505 1.1124752739665 0.266768884966841 0.0167923162109079 27.3475790291137 0.000614033007932113 0.999510455179735 FAM216A other 1 1 1 1.1124752739665 0.000614033007932113 7.88655114340822e-05 14.5649776352948 19.8221487762192 0.734782984414311 0.463011474655213 -171.670360723088 43.7543114580403 -3.92350730710772 0.000106911302742376 ZBTB48 other 0.68699747010229 1 1 0.734782984414311 -3.92350730710772 0.219589747274776 68.5091842653056 56.1078716942664 1.22102625169271 0.222974959362997 -119.978190889314 131.225119722741 -0.914292866661581 0.361251366147922 IGFL2 other 1 1 1 1.22102625169271 -0.914292866661581 0.130350374434086 0.350842934601156 0.991216386525576 0.353951911379245 0.723609488121486 5.82499324672747 2.89002058376242 2.01555424188159 0.0446875180706379 KRT25 other 1 1 1 0.353951911379245 2.01555424188159 2.31854654695936e-06 104.446981706535 22.3382622027 4.67569861785895 4.42840275085303e-06 -42.6531975680209 46.3111657032703 -0.921013257176745 0.357781078730995 MZT1 other 0.0233176226227703 1 0.0508646339962979 4.67569861785895 -0.921013257176745 2.30682340205296e-34 48.2275808009727 3.48040206701714 13.8568992525355 1.65830392839658e-34 -5.38021647848495 14.6572992379464 -0.367067383365965 0.713812134689712 ZNF155 other 3.50567952409988e-30 1 2.52758684766206e-30 13.8568992525355 -0.367067383365965 0.301709092402009 28.1798855126563 55.806316357984 0.504958709904614 0.613943177198888 -257.894746160854 204.582672732512 -1.26058938773396 0.208395724691082 UQCC3 other 1 1 1 0.504958709904614 -1.26058938773396 0.0661160773639733 8.68660523712842 3.75754416423951 2.31177728256628 0.0214266631663377 6.05498290731771 16.1961206126592 0.373853903173889 0.708761364710251 FBXO48 other 1 1 1 2.31177728256628 0.373853903173889 0.00505184387693249 -12.962272560323 9.6794556591713 -1.33915304917392 0.181477250888355 -70.5569035640335 21.6526743275971 -3.25857686198634 0.00124083441606969 ATP6V0E2-AS1 other 1 1 1 -1.33915304917392 -3.25857686198634 0.834320448435727 94.9251505973666 220.103826353692 0.431274422484725 0.666562908901392 -165.447036980536 558.258976340013 -0.296362519892146 0.767147924929217 CD177 other 1 1 1 0.431274422484725 -0.296362519892146 0.515479413490892 -3.11126334289773 4.82822556926587 -0.644390635496096 0.51978962999599 -15.0630408049816 13.9167112761797 -1.08237072006833 0.279913073518985 PSG5 other 1 1 1 -0.644390635496096 -1.08237072006833 5.83796792030786e-07 41.9815373131605 16.834162469142 2.4938298766045 0.0131465909996873 -110.112666426079 37.6835504557243 -2.92203534684065 0.00372736529317633 ZNF783 other 0.00614154225216387 1 1 2.4938298766045 -2.92203534684065 6.19956232650167e-05 11.2431727602552 3.59921849187597 3.12378167250276 0.00195030539966072 -9.28598700927478 8.05690998221053 -1.15254943021308 0.249963757060893 ZNF425 other 0.546863392820712 1 1 3.12378167250276 -1.15254943021308 0.002071354549421 37.4550322354454 11.2199756706223 3.33824540578242 0.000942858349757148 -63.3944560409394 63.4443867162186 -0.999213000899472 0.318448856948129 FAM83A-AS1 other 1 1 1 3.33824540578242 -0.999213000899472 0.802490539052267 -6.25846680523289 9.69607651955275 -0.645463842267777 0.519090626714286 -11.5330038850116 34.2789749329421 -0.336445413189073 0.736756220552651 LRRC10B other 1 1 1 -0.645463842267777 -0.336445413189073 0.411506588626216 2.58208547847517 7.50733278537727 0.343941790285964 0.731115952944612 25.2657680442316 19.0510042185408 1.32621712506066 0.18571357228697 C12orf73 other 1 1 1 0.343941790285964 1.32621712506066 0.000459450151759252 553.843307161905 141.366789286134 3.91777524239372 0.000109432035293474 417.421655674853 223.536722899684 1.86735159333162 0.0627723448464892 PCDHGA1 other 1 1 1 3.91777524239372 1.86735159333162 0.207148641001257 17.9349206857234 10.5062913977648 1.70706484397901 0.0888310763809946 17.6342931052637 17.5149308147354 1.00681488792567 0.3148244385151 PCDHA9 other 1 1 1 1.70706484397901 1.00681488792567 0.231257045688135 17.4471000759586 10.5392146831732 1.65544593221111 0.098865974235467 16.5497105927381 17.5698168867364 0.941939844872925 0.346971354454927 PCDHA8 other 1 1 1 1.65544593221111 0.941939844872925 0.205802885979858 18.0166339239404 10.5286200290165 1.71120563514376 0.0880631842343335 17.6779845497982 17.5521546472709 1.00716891487433 0.314654587500963 PCDHA7 other 1 1 1 1.71120563514376 1.00716891487433 0.219681484626366 18.1681340017558 10.7953160480965 1.68296453024729 0.0934086147584093 17.3279775500785 17.9967608499645 0.962838684946608 0.336393725237937 PCDHA5 other 1 1 1 1.68296453024729 0.962838684946608 0.467795461418998 14.0306306759727 12.2129189586361 1.14883515754858 0.251527069279348 15.9997837782899 20.3600321472131 0.785842756170693 0.432571688089487 PCDHA4 other 1 1 1 1.14883515754858 0.785842756170693 0.189095378406278 18.8891493593608 10.827945306027 1.7444814159568 0.0820858110425347 19.2821690873317 18.0511567517677 1.06819575900273 0.286279711345471 PCDHA2 other 1 1 1 1.7444814159568 1.06819575900273 0.0675011973980157 26.6950379682881 11.8904697268743 2.24507850248786 0.0254817712797084 25.7352031665607 19.8224803345179 1.29828370275877 0.195173923826647 PCDHA1 other 1 1 1 2.24507850248786 1.29828370275877 3.33956103153872e-07 83.2103593756756 18.8468843256845 4.41507242989106 1.38535212505e-05 -49.3896825476046 34.9814474778062 -1.41188218637721 0.158962408494951 TRIM13 other 0.00358000942580951 1 0.153912621093055 4.41507242989106 -1.41188218637721 0.443137807128844 -23.3784002030316 18.3007233049478 -1.27745771647785 0.202369625509066 -26.6059264576643 46.7302447679679 -0.569351318183162 0.56951842375465 SPIRE2 other 1 1 1 -1.27745771647785 -0.569351318183162 0.019533396630876 -4.92638611345136 1.87421832450093 -2.62850173272271 0.00899249135681912 -6.11983275426295 4.56127748412436 -1.34169271121154 0.180652935211885 SLFN12L other 1 1 1 -2.62850173272271 -1.34169271121154 1.43912066488029e-08 56.3403599707099 15.7847337303698 3.56929428985622 0.000413341045777396 -94.5043468865194 34.7208248873184 -2.7218347257941 0.006851004491333 SLC35B4 other 0.000165700353354317 1 1 3.56929428985622 -2.7218347257941 0.304297994056401 7.11082286979313 5.62825199151401 1.26341586704264 0.207362334349861 -3.25660293901087 14.5795169812522 -0.223368369692805 0.823391789765 SYCE1L other 1 1 1 1.26341586704264 -0.223368369692805 0.75655892656237 -4.71285380093709 16.8185673332883 -0.280217316228186 0.779492409542105 22.1272126019736 44.0634051180545 0.502167559286224 0.615896103638494 TMEM231 other 1 1 1 -0.280217316228186 0.502167559286224 0.0999305852091637 11.3290454929407 13.2063560414848 0.857847952709517 0.391620481176513 -29.8951047825913 19.7645093260176 -1.51256498653564 0.131380233121897 CCNI2 other 1 1 1 0.857847952709517 -1.51256498653564 0.00187041204231484 45.4084531542407 13.1742637788198 3.44675451445291 0.000643150234012325 -42.4531853278544 66.7726731230019 -0.635786817305508 0.52536980477661 TRIQK other 1 1 1 3.44675451445291 -0.635786817305508 2.09127607464465e-20 79.1397104845399 8.33828388455443 9.49112690096049 5.55355718322066e-19 -75.0947796813216 38.5885314630925 -1.94603880567844 0.0525279562512285 SDHAF1 other 3.04301581621543e-16 1 8.20538073820852e-15 9.49112690096049 -1.94603880567844 3.56959724689262e-36 434.915136247852 31.0317701084606 14.0151571994688 4.39572747342723e-35 -210.760991474521 146.49871237923 -1.43865422467974 0.151231988660471 PSENEN other 5.43649660701747e-32 1 6.70392396972386e-31 14.0151571994688 -1.43865422467974 0.00191436257064125 7.94902739356599 2.9221077744709 2.72030602807089 0.00688087534481034 -7.56750331605049 7.28744974463485 -1.0384295715551 0.299859037561748 C11orf91 other 1 1 1 2.72030602807089 -1.0384295715551 0.820126015676547 0.548088015013532 1.4992597309347 0.365572424647082 0.71492568427727 -2.22310525766752 5.67043375150041 -0.392052064285079 0.695280720162666 LINC00654 other 1 1 1 0.365572424647082 -0.392052064285079 0.0616263234285653 43.898560395232 18.6417848593108 2.35484749590952 0.0191396462338542 -5.00559253809373 89.4076902313752 -0.0559861520316644 0.95538810911091 ZBTB10 other 1 1 1 2.35484749590952 -0.0559861520316644 0.000376886974145751 25.1369133100126 16.8889392931668 1.48836542506746 0.137648648507023 -79.8594104789932 28.9258823968845 -2.76082884467492 0.00610131039181679 C4orf46 other 1 1 1 1.48836542506746 -2.76082884467492 4.70624482147652e-05 100.487410288246 63.6507433434979 1.57873113509382 0.115395050530114 -422.572802109217 136.303502317165 -3.1002343661422 0.00210719290689083 LGR4 other 0.421303036418578 1 1 1.57873113509382 -3.1002343661422 0.00653288083217188 -275.600456587281 114.824516823907 -2.40018825430754 0.0169593652237698 -893.834202632623 307.375670347354 -2.90795365040614 0.00389310247046097 PSMB10 other 1 1 1 -2.40018825430754 -2.90795365040614 2.82737434719294e-05 48.1033693609204 11.1411415869798 4.31763378872564 2.10593369510287e-05 93.0066962825488 38.1785844299953 2.43609598603864 0.0153919703373676 VIT other 0.259072311433289 1 0.231084104363638 4.31763378872564 2.43609598603864 0.0971323470601377 2.76121546357978 1.34066383862344 2.05958823086847 0.0402541685107471 6.12776018346622 5.28449516416798 1.15957343002527 0.247095181305659 SPDYE2 other 1 1 1 2.05958823086847 1.15957343002527 7.7035960924045e-17 354.411923473166 52.7836092733034 6.71443139930217 8.69241625703256e-11 -413.507173326294 141.285785590751 -2.92674292461424 0.00367210120105529 E2F4 other 1.08343375443577e-12 1 1.182255535119e-06 6.71443139930217 -2.92674292461424 7.63132729137625e-14 241.647838971477 31.4570172896362 7.68184207506189 1.9858227813733e-13 -249.406136228424 148.751219761179 -1.67666615862947 0.0945967170583891 PDE7A other 1.02793978614838e-09 1 2.81331513437155e-09 7.68184207506189 -1.67666615862947 0.703587398870796 2.57695970069302 5.47463950659542 0.470708564022983 0.638171570987239 10.1530984979119 12.2612534402618 0.828063667991119 0.408255459943782 TMEM170B other 1 1 1 0.470708564022983 0.828063667991119 0.0278543334940007 7.22884189905278 3.57395169800471 2.02264678145722 0.0439435726894606 -19.5237482990575 15.3950867296935 -1.26818046834389 0.205658268609776 MUC12 other 1 1 1 2.02264678145722 -1.26818046834389 2.36229611063745e-12 154.542864583333 43.9292888916915 3.51799149229029 0.000497761683375791 -316.000317982456 64.7378994193349 -4.88122600233887 1.66669670459262e-06 SNX2 other 3.08515872049251e-08 0.0249021154633183 1 3.51799149229029 -4.88122600233887 0.0198240693243491 67.6747322615504 24.0859057135501 2.80972337376037 0.0052635571010369 42.4119337633302 103.286430260766 0.410624451404248 0.681622743854653 SAP25 other 1 1 1 2.80972337376037 0.410624451404248 9.27619877778379e-07 27.1806486486485 6.47792362074242 4.19588902864116 3.52739947760105e-05 -41.193281853282 13.7919953910689 -2.98675287260877 0.00303802327650992 NT5M other 0.00963240481085068 1 0.381029691570466 4.19588902864116 -2.98675287260877 0.940705427892284 5.08188041682149 43.5058091153997 0.116809238125919 0.907084498294796 -37.4133886718277 124.299941564489 -0.300992809818958 0.763615454078886 SARNP essential 1 1 1 0.116809238125919 -0.300992809818958 3.30461608605016e-11 999.96965235377 228.472307196382 4.37676523962377 1.63288622980782e-05 -1895.08789969242 601.406327241733 -3.15109405047995 0.00178036957730012 ADGRG1 other 4.19587104445788e-07 1 0.180564559292149 4.37676523962377 -3.15109405047995 1.14492528188611e-17 955.969558431617 145.250340585636 6.58153058076998 1.92787530109092e-10 -790.069969390741 293.820540955224 -2.68895417189754 0.00754672444926815 IPO7 essential 1.62716781061655e-13 1 2.60475231930394e-06 6.58153058076998 -2.68895417189754 5.26746985004858e-05 200.035018057442 51.385018570053 3.89286651292604 0.000120659061127603 -194.889401540842 139.490580783685 -1.39715097926982 0.163339234292236 PRR13 other 0.468857491352824 1 1 3.89286651292604 -1.39715097926982 3.95082690106347e-05 82.6616725544343 20.9041423998225 3.95432019995885 9.48361390857568e-05 -125.240645604978 90.6191123028807 -1.38205553356537 0.167933896370031 TECPR1 other 0.356759669166032 1 0.985157812822841 3.95432019995885 -1.38205553356537 0.0531854329232069 1.07392835154687 3.65709255992004 0.293656322324627 0.769210897444804 -19.5186477767066 9.67812744740691 -2.01677937005638 0.0445534551182149 MT1H other 1 1 1 0.293656322324627 -2.01677937005638 0.000352799405598705 15.4070821148223 9.44286366061676 1.63161120064461 0.10374510731016 -63.5831917362669 24.9895884445251 -2.54438731063605 0.011416535619384 MT1A other 1 1 1 1.63161120064461 -2.54438731063605 0.411201799655791 19.1141317470543 14.4436270735691 1.32336092933554 0.18666010299676 9.43373201722024 28.4052598235079 0.332112153729112 0.740022002390102 C15orf59 other 1 1 1 1.32336092933554 0.332112153729112 0.0883639611516737 15.5656264429737 10.0442634400669 1.54970312515718 0.122201185763702 -18.559984162731 26.5811324421121 -0.698239031130466 0.485534802058699 MT1M other 1 1 1 1.54970312515718 -0.698239031130466 0.0639636266642593 -58.1806847038615 43.2784576316689 -1.344333598924 0.179798730430759 -180.486388079767 79.2542711945011 -2.27730802844465 0.0234315378794262 CFI other 1 1 1 -1.344333598924 -2.27730802844465 0.0416703494371426 486.620164149015 243.747478236134 1.99641107128745 0.0467663327211182 -1133.76761025733 1053.80772771105 -1.07587710779077 0.282821526344524 SAMD9 other 1 1 1 1.99641107128745 -1.07587710779077 0.0565675027429519 34556.6557950922 25831.1084367045 1.33779221591549 0.181917104146249 -118921.447649406 70121.5338320844 -1.69593334815207 0.0908741376045488 KRT6A other 1 1 1 1.33779221591549 -1.69593334815207 7.54548059466065e-14 43.2522240549382 8.26825234668062 5.23112046432669 3.09054808556233e-07 -69.1437576563297 22.1387803609186 -3.12319633372345 0.0019562335126018 CNEP1R1 other 1.01652714571268e-09 1 0.00377108677400316 5.23112046432669 -3.12319633372345 0.416750648439446 786.137876057116 625.731584040402 1.25635000071589 0.209911253426701 -286.603276491521 1723.01979807844 -0.166337773257828 0.867996850803503 KRT81 other 1 1 1 1.25635000071589 -0.166337773257828 0.00861878844978131 -45.8679487686288 15.2613765363957 -3.00549224109908 0.0028638536939131 -6.9782429894149 44.9356498798125 -0.155294137462779 0.876688585439931 EXOC3L4 other 1 1 1 -3.00549224109908 -0.155294137462779 0.000105004146623236 11.7682174357775 4.32779601005257 2.71921722013754 0.00690190151769974 -11.9966709680791 5.97844442875129 -2.0066542578175 0.045630064642449 ATP6AP1L other 0.902195627786847 1 1 2.71921722013754 -2.0066542578175 1.37378817998888e-20 649.824609711596 74.6567502914903 8.70416415360187 1.86425278727343e-16 -680.412157343603 224.775397970615 -3.02707575422713 0.00267444907934195 CCDC85C other 2.00202151469779e-16 1 2.71472490882758e-12 8.70416415360187 -3.02707575422713 0.0861631768192006 -10.2457251212779 5.25822461080826 -1.94851416202683 0.052227273524731 -17.497867027597 10.2713481360727 -1.70356089539454 0.0894340047912805 C2CD4B other 1 1 1 -1.94851416202683 -1.70356089539454 0.102661080976306 22.7090342884031 11.5463388819628 1.96677358256634 0.0500785685519681 -4.59285578160392 24.3613012383227 -0.188530806982465 0.850580824839428 RGL3 other 1 1 1 1.96677358256634 -0.188530806982465 6.09570690850852e-15 343.737131126503 140.620719092788 2.44442734572911 0.0150475267151427 -1457.95718124048 269.281207529976 -5.41425521154565 1.2101800360403e-07 NAP1L4 other 8.37489172159986e-11 0.00182809796244247 1 2.44442734572911 -5.41425521154565 2.38999181179367e-07 217.021428144702 38.4309140966054 5.64705350487282 3.60438935467523e-08 -5.17000547370343 73.3568500589283 -0.070477473740357 0.943857652626827 TMEM256 other 0.00258262515182424 1 0.000456495911769617 5.64705350487282 -0.070477473740357 2.29415022103763e-05 6.89198143918545 1.51917328838303 4.53666575886224 8.12812770128462e-06 -0.203229682905234 4.37173929741566 -0.0464871459799472 0.962951343449263 CHKB-AS1 other 0.211910655917246 1 0.0918397148968149 4.53666575886224 -0.0464871459799472 0.627155435843521 19.9018550356508 42.2713122474968 0.470812330573659 0.638099584551776 113.849543482665 121.644553862848 0.935919775011281 0.350029179743884 CPT1B other 1 1 1 0.470812330573659 0.935919775011281 1.22724389513573e-12 339.602516769616 137.492244439263 2.46997580230523 0.0140383961935702 -1291.699660183 223.077890940054 -5.7903526644427 1.69040905415559e-08 HMGN1 other 1.61345754893495e-08 0.000256570286239736 1 2.46997580230523 -5.7903526644427 0.000713462415433095 35.3052631578945 10.4357346279741 3.38311239376047 0.000806008172480406 -27.0648606811146 29.6284120470504 -0.913476585857357 0.361681824735971 DENND6B other 1 1 1 3.38311239376047 -0.913476585857357 1.77543620233801e-06 821.027550050498 192.82582996783 4.25787121044661 2.72252189382543e-05 -1244.00127725301 695.781600788608 -1.78791919165877 0.0747440947426224 EIF3CL essential 0.0179958213468981 1 0.296428183799713 4.25787121044661 -1.78791919165877 6.28812500146166e-05 61.9565229380366 23.4220684206307 2.6452199620194 0.00856927898967046 -211.169969285855 82.1371493800865 -2.57094348756461 0.0105966594825774 LCMT1 other 0.554109575128801 1 1 2.6452199620194 -2.57094348756461 0.0903613442867169 26.4207798974115 12.0617634314396 2.19045747726608 0.0292145144682886 22.8555749857281 40.5455837758889 0.563700725387498 0.57335387276009 MFSD2B other 1 1 1 2.19045747726608 0.563700725387498 3.54267103751056e-05 30.2789257776605 7.33469905717916 4.12817561315261 4.67656378743107e-05 -18.0399872154439 18.605935785371 -0.969582364657406 0.332991570351794 CDPF1 other 0.321072276129582 1 0.500532622168747 4.12817561315261 -0.969582364657406 0.269243694641797 599.183168761222 393.145786152247 1.52407374024145 0.128481024411138 8.92235188509957 845.287989575035 0.0105553988642205 0.991584764678217 HTN3 other 1 1 1 1.52407374024145 0.0105553988642205 0.125979660683919 13.8993651119872 9.21387316642279 1.50852576988353 0.132409760792487 -29.8543336385518 30.0636493251809 -0.99303758221881 0.321444281565691 LIN52 other 1 1 1 1.50852576988353 -0.99303758221881 0.000206724986838541 21.1247879487004 6.13359870887676 3.44410988578824 0.00065128012042913 -12.0990703671032 10.3694306871756 -1.16680179771748 0.244181452477608 SMIM11A other 1 1 1 3.44410988578824 -1.16680179771748 0.361973889160375 4.12898780730391 2.95628896411679 1.39667936978464 0.163480948594298 5.57051981454487 9.10462538047369 0.611834049371403 0.54108336704896 DPF3 other 1 1 1 1.39667936978464 0.611834049371403 0.676467356058102 -1.47642433891618 2.62949141636326 -0.561486654692398 0.574860064366325 -5.43246108158106 6.84494585010375 -0.79364558910261 0.427991726688968 CYP2D7 other 1 1 1 -0.561486654692398 -0.79364558910261 5.4512622385282e-13 59.2825707160291 8.01218567567222 7.39905103497934 1.27146681047672e-12 -51.0115636877689 38.5129456496334 -1.32453030603891 0.186293264928705 ETFRF1 other 7.22128708737831e-09 1 1.78259646828836e-08 7.39905103497934 -1.32453030603891 3.63143620264537e-32 143.20130485322 10.6017360616984 13.5073448367172 3.28120757445401e-33 26.169255268178 23.7487139905749 1.10192304638322 0.271323221002813 C17orf107 other 5.50416785234959e-28 1 4.99662289437856e-29 13.5073448367172 1.10192304638322 3.19118548163509e-05 115.48444336026 30.753808524695 3.75512656481316 0.000206652241847774 -73.7473004714355 51.9347492781559 -1.41999916234224 0.156606361570877 ITSN1 other 0.290589349957692 1 1 3.75512656481316 -1.41999916234224 0.00740097307873844 252.4414173498 92.7771503697189 2.72094385679896 0.00686565351985955 -220.470662021173 284.937788428574 -0.77375016924594 0.439649777906893 ITPRIPL2 other 1 1 1 2.72094385679896 -0.77375016924594 0.000689603579693663 -0.643090115208649 25.1562352130363 -0.0255638456932296 0.97962115770173 -157.314324793519 45.3217918779274 -3.4710526277787 0.000589601635247889 DENND1C other 1 1 1 -0.0255638456932296 -3.4710526277787 6.96475523479192e-11 45.7438121057895 9.53091941255157 4.79951724757509 2.47047951643194e-06 -56.5135988231662 16.0951093157684 -3.51122802053913 0.000511828365099886 CRYZL1 other 8.76096560984476e-07 1 0.0288132026001457 4.79951724757509 -3.51122802053913 0.000593768438066834 21.9152258481714 5.67545019838137 3.86140747996019 0.000136427102569461 4.00183355195442 23.3394844137438 0.171461951815777 0.863968919100385 RP9P other 1 1 1 3.86140747996019 0.171461951815777 1.97934673438902e-20 205.535959045209 20.0892716934058 10.2311304352897 2.28284240087702e-21 14.1755261966914 141.568767938137 0.10013173387852 0.92030425838561 C5orf51 other 2.88054330255634e-16 1 3.40851198874948e-17 10.2311304352897 0.10013173387852 1.3701296907881e-05 73.6328646097435 19.6511790956275 3.74699473509594 0.000212370731529837 -52.8101362985422 39.7600512791406 -1.32822103089812 0.185054582908235 CATSPER2P1 other 0.129244333732042 1 1 3.74699473509594 -1.32822103089812 0.180024724610109 15.0306864135201 8.1075561960851 1.85391085180242 0.0646748516760319 8.76182425822341 24.4058377605266 0.359005265223657 0.719828650384308 CYS1 other 1 1 1 1.85391085180242 0.359005265223657 1.61502899622203e-34 97.3968854649787 7.11439792352599 13.6901093405115 8.93240640681089e-34 -32.9982801717521 23.9457370500287 -1.37804403776799 0.169170889659167 PLPP6 other 2.45516708005672e-30 1 1.36076279201357e-29 13.6901093405115 -1.37804403776799 0.171599223903788 -2.44088577731065 1.32279575243491 -1.84524766791671 0.0659281967980992 -4.87866503556913 6.9287625650335 -0.704117797337964 0.481873089278047 KLRC2 other 1 1 1 -1.84524766791671 -0.704117797337964 0.507536995612381 4.51586743583807 3.98754193539441 1.13249402990702 0.258274649486934 4.94342503463133 6.46751224583097 0.764347224517111 0.44522359739919 C1QTNF9B other 1 1 1 1.13249402990702 0.764347224517111 1.02950427655597e-12 37.5438184132371 4.90933668414502 7.64743199106449 2.43772834194683e-13 -8.36695630038184 27.5694537250466 -0.303486473973205 0.76171699170692 C1RL-AS1 other 1.35585713222421e-08 1 3.44841051251798e-09 7.64743199106449 -0.303486473973205 1.74376662545974e-20 179.313982575482 17.8938559634659 10.0209805500608 1.01300262532396e-20 -57.1121858367937 85.600634372348 -0.667193488173995 0.505132392379792 ZNF316 other 2.53909858333193e-16 1 1.50856350963244e-16 10.0209805500608 -0.667193488173995 0.250582446226874 3.09393818049782 1.87922189666697 1.64639321518406 0.100664532080217 1.09538485453821 5.38169426285172 0.203539034556336 0.838843109609753 SRRM2-AS1 other 1 1 1 1.64639321518406 0.203539034556336 0.00934439877348179 23.1774070947385 7.57686076328947 3.058972286654 0.00240982419807823 15.4001994431801 12.5328357795534 1.22878809824546 0.220059812674365 ONECUT3 other 1 1 1 3.058972286654 1.22878809824546 0.0635958983644496 3.60195851546934 10.4386077582169 0.345061199625402 0.730275056298432 -64.1240542992358 29.8939659995409 -2.14505008469671 0.0327013041137964 CEMP1 other 1 1 1 0.345061199625402 -2.14505008469671 1.99055247363725e-08 386.3626459034 90.9602180667296 4.24760025992857 2.83621269337427e-05 -776.138608787746 258.459404292138 -3.00294203228323 0.00288455810468315 RNPS1 other 0.000227977974805674 1 0.308353044023651 4.24760025992857 -3.00294203228323 0.386376500094567 76.7410878939609 61.6858415661809 1.24406323956248 0.214386785837635 -46.9104670390203 167.549227077424 -0.279980205562769 0.77967358798332 NYNRIN other 1 1 1 1.24406323956248 -0.279980205562769 8.42951566753997e-21 86.9574113106897 8.41736528130543 10.3307161332083 1.05573417492341e-21 12.3836471855638 55.6110729374954 0.222683119232074 0.823928316440559 DNAJC19 other 1.23037210683413e-16 1 1.57800587125801e-17 10.3307161332083 0.222683119232074 0.218680788199573 7.38458001562373 4.29799710512315 1.71814448335049 0.0867436469435898 5.54839533041924 6.51600118646379 0.851503118499328 0.395130692509571 DOK6 other 1 1 1 1.71814448335049 0.851503118499328 1.32488084025492e-09 496.59038074134 127.419189634726 3.89729664868315 0.000118501512706511 -1442.12951248992 359.35315323206 -4.0131260836847 7.46737815953639e-05 JPT2 other 1.59330169849057e-05 1 1 3.89729664868315 -4.0131260836847 0.00844044866897938 -183.751960992337 411.15083167314 -0.446921049009132 0.655236290744322 -1813.18318600498 667.138293748953 -2.71785206005171 0.00693092508054872 SERPINB11 other 1 1 1 -0.446921049009132 -2.71785206005171 0.023093576186761 -691.197732718337 462.942371822535 -1.49305350900846 0.13641465278319 -2067.3898499113 751.175870871907 -2.75220481657861 0.00625932410990557 SERPINB4 other 1 1 1 -1.49305350900846 -2.75220481657861 4.16696231685433e-05 1674.08023479352 884.435042791871 1.8928244063114 0.0592862670996749 -3077.76721831726 1433.22408884156 -2.14744312650016 0.0325112144651547 SERPINB5 other 0.375068278140058 1 1 1.8928244063114 -2.14744312650016 0.231355713672948 42.3295223340117 24.7927813756314 1.70733253734965 0.0887363249618307 1.9576590197799 150.680460232669 0.0129921226465398 0.989642224559268 ZDHHC11B other 1 1 1 1.70733253734965 0.0129921226465398 0.0587004015771912 12.9018037081822 24.5841899041932 0.524800847962113 0.600089614535849 -103.323172016416 53.1776293560841 -1.94298191302494 0.0529062195613249 HERC2P9 other 1 1 1 0.524800847962113 -1.94298191302494 0.677917712247223 -17.5720362035709 38.8835337659064 -0.451914589588518 0.651641528892561 -90.1469055150447 104.898117944784 -0.859375814182825 0.390786726311573 HBA1 other 1 1 1 -0.451914589588518 -0.859375814182825 0.912307796399984 3.93680987434953 13.2627589328291 0.296831895557175 0.766789249167109 11.8672864576722 29.7054274589897 0.399498929078056 0.689794637309686 ATP10A other 1 1 1 0.296831895557175 0.399498929078056 5.70527538927077e-13 32.8209247981141 4.33286771319672 7.57487349501823 3.94695132469466e-13 67.6097973729833 26.29197111741 2.57149975827463 0.0105800048000567 ANKUB1 other 7.55264356031665e-09 1 5.56678014834934e-09 7.57487349501823 2.57149975827463 0.000360234383584762 5.5954438869262 1.60507680909445 3.48609104263553 0.000559482703571556 -6.74803098453869 5.94552649348419 -1.13497618620218 0.257245455198856 TSSK2 other 1 1 1 3.48609104263553 -1.13497618620218 0.00283043936762637 7.63738306992897 2.2480756143785 3.39729812515242 0.000767031013044033 10.7014766393418 10.3320575256791 1.03575465126327 0.30110359650065 FOXL2NB other 1 1 1 3.39729812515242 1.03575465126327 0.03134309832287 242.109673803428 100.853155803837 2.40061574547395 0.0169381294744596 -29.2992238999965 235.656185111045 -0.124330383631519 0.901131753429467 HCP5 other 1 1 1 2.40061574547395 -0.124330383631519 0.542293865381404 3.10445213547698 4.24384629190206 0.731518514560901 0.464997842014184 -11.6294383491552 17.1399074145096 -0.678500651602725 0.497944679499335 COL6A6 other 1 1 1 0.731518514560901 -0.678500651602725 6.90062132637624e-36 343.005327026108 23.7555233233923 14.4389716175332 1.14548906116568e-36 127.123444417195 100.887520843098 1.2600512268995 0.208577693397544 RAB12 other 1.05055059072752e-31 1 1.74893269858776e-32 14.4389716175332 1.2600512268995 0.17761445658629 -3.59369313073978 3.98370085261547 -0.902099144412505 0.367709109101336 -31.4969304850956 17.9614576531868 -1.75358431889336 0.0804964430315596 TMEM200C other 1 1 1 -0.902099144412505 -1.75358431889336 0.739208709105946 2109.63066281578 2758.04574531647 0.764900533792166 0.444894493433913 1007.30516945231 6226.15649636633 0.16178603445644 0.871576453262183 HLA-A other 1 1 1 0.764900533792166 0.16178603445644 3.10682503445494e-10 510.627688420885 76.4328031821402 6.68074003780882 1.05467756991916e-10 -82.7153822345142 299.59371953502 -0.276091843189809 0.782655744734783 HACD2 other 3.83071526748294e-06 1 1.4324630754642e-06 6.68074003780882 -0.276091843189809 0.316683031744308 18.7320276071876 14.9213769746568 1.25538196903697 0.210256068604216 -33.5686939310013 61.2962265589846 -0.547646989308527 0.584316086495471 CFAP44 other 1 1 1 1.25538196903697 -0.547646989308527 5.64414350976986e-09 12.5795066354734 2.27301786790639 5.53427529677098 6.55580719797082e-08 -14.4838761102255 9.28273760470086 -1.56030222193189 0.119686226312785 LNP1 other 6.63073979527764e-05 1 0.000822032664553561 5.53427529677098 -1.56030222193189 0.0349130039882741 77.0974733491292 42.3364398884955 1.82106652217773 0.0695927193747318 151.084666090062 59.0912653464597 2.55680201133338 0.0110560941535902 VGLL3 other 1 1 1 1.82106652217773 2.55680201133338 0.718868546661877 2.90218515976354 11.8444728774851 0.245024425298 0.806594571824126 13.3471586776351 16.9531030351542 0.787298859091357 0.431689661475671 PRSS50 other 1 1 1 0.245024425298 0.787298859091357 7.15846549942597e-18 257.258076855016 47.2018532451314 5.45016899059045 1.00856758199609e-07 -321.842896083743 75.9752510233638 -4.23615442856214 2.97893969327277e-05 ANKRD28 other 1.01950865642825e-13 0.432988884417197 0.00125566663958513 5.45016899059045 -4.23615442856214 0.00170195414543538 0.979290124917994 3.21371359207523 0.304722277471412 0.760775765747777 -15.6318787747621 5.17732760043886 -3.01929489133294 0.00273742747867521 COLQ other 1 1 1 0.304722277471412 -3.01929489133294 7.11023761975143e-33 67.653638312694 7.25071412953625 9.33061724735534 1.81007766370237e-18 -51.7364311463103 11.680979437094 -4.4291175602978 1.30055307192715e-05 METTL6 other 1.07862304691629e-28 0.190934196489624 2.66751145299818e-14 9.33061724735534 -4.4291175602978 3.65776411247249e-25 83.6522389333264 11.6105359783391 7.20485592477295 4.24133240552106e-12 -95.7724150942616 19.7853303607806 -4.84057700063003 2.02326015117016e-06 THUMPD3-AS1 other 5.45665250298646e-21 0.0301910879757612 5.9005416425609e-08 7.20485592477295 -4.84057700063003 0.265264995422117 -10.6398918403054 8.66635669044209 -1.22772373909326 0.220488147849139 -50.3821627607754 40.3998659158336 -1.24708737562987 0.213312929433822 XKR4 other 1 1 1 -1.22772373909326 -1.24708737562987 3.61477231167222e-08 6.21288467516319 1.22058269977471 5.09009727592399 6.18721221005382e-07 0.997140192726159 2.89435387584925 0.34451219011137 0.730692488602871 SNORA25 other 0.000408324680326493 1 0.00744816605846278 5.09009727592399 0.34451219011137 1.12587147787671e-19 6.1170929437364 0.884426694016622 6.91644992752947 2.61487531254732e-11 -3.97442834939383 2.09723096206758 -1.89508376582215 0.0590025970501278 SNORA18 other 1.63082483570441e-15 1 3.59022380412747e-07 6.91644992752947 -1.89508376582215 1.75066594919109e-16 6.21372956170344 0.881217797587496 7.05129830413631 1.13933051624863e-11 -1.05023189306807 2.08962174245587 -0.502594259874881 0.615602991939924 SNORA8 other 2.45425859417098e-12 1 1.57489657261049e-07 7.05129830413631 -0.502594259874881 0.0102087828387385 1.82136260444538 0.674467934459838 2.70044358136026 0.0072978885337099 -1.9694656864144 2.21520332569368 -0.889067682217238 0.37464299245101 MIR130B other 1 1 1 2.70044358136026 -0.889067682217238 6.11603488050709e-20 5.9870724277277 1.03832326663097 5.76609676402019 1.94582924292201e-08 -8.3969424930059 2.46216415463902 -3.41039100792083 0.000733765816983912 SNORA40 other 8.87008538719943e-16 1 0.000249280184310738 5.76609676402019 -3.41039100792083 0.233901588806923 390.102196787126 314.211101463499 1.24152900699609 0.215319643677223 691.873468070768 454.91021771788 1.52090113856234 0.129272117936542 GPX3 other 1 1 1 1.24152900699609 1.52090113856234 0.119822702993308 52.2569941878549 82.8043367617427 0.631090064017018 0.528437831785904 515.578013049142 250.17165739556 2.06089697936459 0.0401308675930981 DIO2 other 1 1 1 0.631090064017018 2.06089697936459 0.0163920059239573 178.461423275472 62.9590359967724 2.83456410108663 0.00488430018580873 53.0456095171535 227.555065587696 0.23311109062835 0.815826066765345 SELENOH other 1 1 1 2.83456410108663 0.23311109062835 0.00269417786927414 25.4131723664757 7.33470649184382 3.46478381851205 0.000606452258047082 -10.4749665810951 28.2990121533334 -0.370153082529461 0.711524499999594 GNRHR2 other 1 1 1 3.46478381851205 -0.370153082529461 3.46240954948639e-23 353.586695115792 33.4823200181617 10.5604000835067 1.4540411737562e-22 -237.18189863864 172.129716444348 -1.37792534338674 0.169189119549246 STK38L other 5.12367365132996e-19 1 2.17844448652154e-18 10.5604000835067 -1.37792534338674 7.37855945383842e-11 74.9575949523078 31.6101829543801 2.37131164537981 0.0183167908877507 -201.7368672927 45.2983396691519 -4.45351570865813 1.16882306710707e-05 SACM1L essential 9.27042209780259e-07 0.171723485019371 1 2.37131164537981 -4.45351570865813 5.81743608390606e-06 218.649368887517 56.228288015877 3.88860085560096 0.000122997965903488 -416.409990738531 173.367000627571 -2.40189879983601 0.0168890109617939 TSN other 0.0567141843820002 1 1 3.88860085560096 -2.40189879983601 0.0400836294416034 121.421496395529 49.4064233455347 2.457605472599 0.0145216711147197 -27.0447357775243 129.988676693601 -0.208054551099646 0.835319979168451 SLC48A1 other 1 1 1 2.457605472599 -0.208054551099646 0.266992537929021 1.67892873162293 1.26811239010325 1.32395893670452 0.186485839459254 -2.33151872602309 4.36243856535708 -0.534453079646347 0.593408735793274 MIR762 other 1 1 1 1.32395893670452 -0.534453079646347 0.000623503263835592 11.6388600416173 6.17313223525036 1.88540591681417 0.0602893800272331 -25.0842614862544 11.3223678961949 -2.21546073367607 0.0274387608163884 PRR22 other 1 1 1 1.88540591681417 -2.21546073367607 1.53779251242797e-40 29.7619623813694 1.89896566303958 15.6727227672621 1.76479998774449e-41 14.7235039686481 9.92081886739902 1.48410168207297 0.138766251765147 TAS2R14 other 2.3495931797387e-36 1 2.69979102125151e-37 15.6727227672621 1.48410168207297 2.58116193789163e-11 19.6795786377026 2.79751503170245 7.03466412680057 1.21753668906108e-11 2.72452943884483 10.2368737078997 0.266148583697221 0.790296181369061 SNORD86 other 3.28788407648636e-07 1 1.6822704432757e-07 7.03466412680057 0.266148583697221 0.563070740563681 5.51852784422344 11.128357454836 0.495897787846964 0.620306936056561 29.7035791781147 29.2900803200834 1.01411736852588 0.311292903150034 LINC01089 other 1 1 1 0.495897787846964 1.01411736852588 0.341207535100451 3.73204076687923 2.57528249924723 1.44917723316573 0.14850717990495 4.92206195452134 6.0364868721014 0.815385183270993 0.41560687328823 CTAGE1 other 1 1 1 1.44917723316573 0.815385183270993 2.51999501438376e-08 88.1625454725993 14.6324591113534 6.0251352695866 4.64324073180293e-09 34.7872485631727 27.0517789675606 1.28595049534037 0.199390059283009 C17orf51 other 0.000287002232188167 1 6.06407239573463e-05 6.0251352695866 1.28595049534037 0.0406812134449597 22.0076224054026 8.92596652746986 2.46557303768434 0.0142070644166491 -5.76547865184771 18.8054561082037 -0.306585419607694 0.759359596320353 RNF208 other 1 1 1 2.46557303768434 -0.306585419607694 0.411433511006241 4.69044754786647 3.57460522677767 1.31215819658348 0.190410160100678 -1.49358986902388 10.4275169796167 -0.143235429100091 0.886194683855289 KRTAP3-1 other 1 1 1 1.31215819658348 -0.143235429100091 0.000415224574134419 12.5825072453512 3.17849681152438 3.95863453432779 9.29201401934273e-05 3.8745868121663 10.2073431094355 0.37958818182419 0.704502915627749 MAP10 other 1 1 0.966462378151837 3.95863453432779 0.37958818182419 0.0652340370713857 2.00434200849643 0.85414046735721 2.34661871799384 0.0195678709630645 1.07740910502 4.96205043788554 0.217129817301719 0.8282486409109 POU5F1B other 1 1 1 2.34661871799384 0.217129817301719 0.0376917862278889 -13.1440822878353 5.78978906947651 -2.2702178145194 0.0238674437572372 -41.3678257257994 27.3782532626929 -1.51097388605757 0.131794423082473 PTTG3P other 1 1 1 -2.2702178145194 -1.51097388605757 0.0026625968850309 47.7322073557127 18.9563029711499 2.51801247470869 0.0122895873785109 -86.6161912041873 51.507588648922 -1.68161999961922 0.0936181536262255 ZNF580 other 1 1 1 2.51801247470869 -1.68161999961922 0.408928063835716 5.83457041077928 5.75184884457055 1.01438173506364 0.311174231604241 -12.0734304724379 18.6249469620789 -0.648239723689947 0.517299175284295 ZNF611 other 1 1 1 1.01438173506364 -0.648239723689947 0.693799876916147 74.1906123855423 139.639105870609 0.531302545393611 0.595578885441544 -185.345908737222 339.092868538941 -0.546593355194486 0.58504024447522 KLK9 other 1 1 1 0.531302545393611 -0.546593355194486 6.83393471209553e-05 219.055037313433 106.724413670663 2.05252978001273 0.0409337703380529 -848.874378109451 249.59606352945 -3.40099265231116 0.000756822341468909 NUP62 other 0.600019467721987 1 1 2.05252978001273 -3.40099265231116 0.0139624770140624 5.74888088974125 2.10559943613107 2.73028230873034 0.00667851516191261 -8.43914338321514 7.08571578905255 -1.1910078860704 0.234533166627093 SPHAR other 1 1 1 2.73028230873034 -1.1910078860704 0.820285062275923 3.88144531249999 6.16625980479404 0.629465094786034 0.529493750517956 2.19598214285715 14.1277070064946 0.15543797318614 0.876574051850951 CGB8 other 1 1 1 0.629465094786034 0.15543797318614 0.180267364660503 36.2917689134932 19.7034249268826 1.84190155001825 0.0664205698431425 -13.557594370958 67.7955696529527 -0.199977586151421 0.841625932098051 DENND1B other 1 1 1 1.84190155001825 -0.199977586151421 0.00303851526795705 223.0658021276 64.919134944595 3.43605629246253 0.000668648605557972 -23.7222086767942 214.019771068724 -0.110841201998935 0.911812194614074 SFT2D2 other 1 1 1 3.43605629246253 -0.110841201998935 0.00437666889659315 29.5040258144982 15.2164153571183 1.9389603347477 0.0533878277550593 -76.0969420405926 35.1601340536078 -2.16429612937679 0.031183254931692 FGFR1OP other 1 1 1 1.9389603347477 -2.16429612937679 0.434489980465205 2.51673269225726 2.38763634812824 1.0540686793574 0.292646690807351 -6.38739980599384 8.19731640709398 -0.779206204663049 0.436434117990185 RPL31P11 other 1 1 1 1.0540686793574 -0.779206204663049 6.3393382252778e-05 70.5482041238656 38.3545469319926 1.83937002955494 0.0667928660426631 -300.912470225066 84.505840198326 -3.56084821497375 0.000426148476331597 SCAF8 other 0.558115337353457 1 1 1.83937002955494 -3.56084821497375 0.960991426525913 -3.04460295683666 13.6100429750468 -0.223702670330928 0.823131414322996 8.47181263192265 47.6400599875712 0.177829596229158 0.858969319339526 CFAP45 other 1 1 1 -0.223702670330928 0.177829596229158 0.830641735554002 13.3219196312163 35.5099199221504 0.375160508962634 0.707789630356317 -60.4774840136564 123.204956555734 -0.490868920409857 0.623855609630083 ACKR1 other 1 1 1 0.375160508962634 -0.490868920409857 0.00307391739533666 38.2919079214013 13.2258171508172 2.89523947630224 0.00405688373977436 -24.0471286326154 30.9187706354442 -0.777751771444902 0.437306611386326 ZNF254 other 1 1 1 2.89523947630224 -0.777751771444902 0.000381629009583493 34.3701936704707 8.71737802194986 3.94272149078869 9.90005358171617e-05 -39.9010602251442 53.5071635654082 -0.745714359842087 0.456387393716855 TCTEX1D2 other 1 1 1 3.94272149078869 -0.745714359842087 1.31306724957247e-06 16.5718195239404 4.07551055263271 4.06619472822497 6.02142818557934e-05 80.0653016125324 25.3410931242614 3.15950465198671 0.00173129737176326 CRYGS other 0.0134807678188612 1 0.637609030570996 4.06619472822497 3.15950465198671 0.845022041974593 102.634579108702 177.322817978416 0.578800744759167 0.563135944535808 68.5327694906478 525.35101993672 0.130451387529242 0.896292316773468 CRIP1 other 1 1 1 0.578800744759167 0.130451387529242 0.302786214051184 -3.41552787193895 4.08929818526266 -0.835235709699063 0.404208164008132 -12.5009425567319 8.13908873862765 -1.53591427224562 0.125547530224658 FAM24B other 1 1 1 -0.835235709699063 -1.53591427224562 2.25753715877968e-06 291.706870544765 58.7477676273456 4.96541200331471 1.12888717107206e-06 -562.58406720926 345.702290712225 -1.62736574886504 0.104665641816864 TRIM59 other 0.0227153388916411 1 0.0134224684640468 4.96541200331471 -1.62736574886504 0.00192574378452046 120.72720243959 34.6313265955778 3.48606924156947 0.000559298674856718 94.3638833320234 138.077813622313 0.683410903290652 0.494846430896191 MLLT11 other 1 1 1 3.48606924156947 0.683410903290652 0.0622272893279603 -2.44616528299444 2.62556927852707 -0.931670439245359 0.352209232820148 -13.6906126675969 5.83373643126466 -2.34680000183502 0.0195448234002592 ASIC3 other 1 1 1 -0.931670439245359 -2.34680000183502 0.00257259415864328 -28.6056952667696 8.79440270284412 -3.25271610060778 0.00126506891221108 -53.4169736876235 19.5761851183959 -2.72867125870336 0.00671046735605456 GIMAP1 other 1 1 1 -3.25271610060778 -2.72867125870336 0.000913788497920558 26.4910172460337 10.4223578294662 2.54174896693126 0.0115027983230479 -50.2056854780485 25.1088456590107 -1.99952184819103 0.046399700154366 CFAP206 other 1 1 1 2.54174896693126 -1.99952184819103 1.91787836269762e-05 3.55856689347597 1.50414571164337 2.36583920422711 0.0185886823719063 -11.8468530567729 3.14345390565521 -3.76873764093055 0.000195528234130605 CCDC183 other 0.178266793812744 1 1 2.36583920422711 -3.76873764093055 0.000237019161753284 63.8222327824007 40.0400973456483 1.59395798245573 0.111945129353402 -236.96220403811 93.258266901991 -2.54092438032484 0.0115339417614897 ARHGEF35 other 1 1 1 1.59395798245573 -2.54092438032484 0.000914538913025421 83.4556721937253 22.1667744535406 3.76489923550404 0.000198319596212405 37.7362653442625 46.2159965604197 0.816519563630498 0.414812365222554 DNLZ essential 1 1 1 3.76489923550404 0.816519563630498 0.000786847863776422 121.819058081346 32.0855650122168 3.79669356095061 0.0001757969858359 8.83293905880044 75.6076656234708 0.116825972419104 0.907072174988508 SUPT4H1 other 1 1 1 3.79669356095061 0.116825972419104 7.56518627363397e-15 427.76798043897 95.9432074053448 4.45855409681811 1.14438579232473e-05 -747.723039062192 174.809594804834 -4.27735697172108 2.50251765129264e-05 NRAS og 1.03786790487984e-10 0.36446667073426 0.127793561428902 4.45855409681811 -4.27735697172108 0.789621294734541 -0.121308878804249 4.57232547036847 -0.0265311119233324 0.978850307846886 -4.79602149977643 7.28440623442101 -0.658395666775665 0.510758808005156 LTC4S other 1 1 1 -0.0265311119233324 -0.658395666775665 0.307285394134105 100.097279962168 105.484101485293 0.948932384622182 0.343406276789599 467.392810715731 349.268012853108 1.33820674529477 0.181825831371893 ANKRD39 other 1 1 1 0.948932384622182 1.33820674529477 4.61897984613346e-07 156.032903076499 42.0557341205408 3.71014574681481 0.000244420822031594 -257.323304996834 94.1864972981136 -2.73206152026621 0.00664561252305045 QTRT1 other 0.00489427104496301 1 1 3.71014574681481 -2.73206152026621 1.48321898127608e-06 66.6817807183236 23.9814660681037 2.78055480548843 0.00574798562787269 -119.180917315453 43.860658269472 -2.71726239454107 0.00694071999835228 CHUK other 0.0151540483316977 1 1 2.78055480548843 -2.71726239454107 2.30242789932073e-12 459.026220185606 109.976328124028 4.17386384884509 3.86390542392348e-05 -767.422261743914 167.113744157702 -4.59221511439366 6.31279300752336e-06 MXD3 other 3.00743132209274e-08 0.0933977725463082 0.416219892265037 4.17386384884509 -4.59221511439366 0.0273423223852695 -101.002139411743 183.950415853752 -0.549072634290991 0.58333852746157 734.411109711846 341.69090670941 2.14934344254125 0.0323567249661671 GSTM2 other 1 1 1 -0.549072634290991 2.14934344254125 3.02517780885571e-18 112.966389632606 15.5632801362717 7.25852061027461 3.00325251877283e-12 -122.21391190858 42.4500337428375 -2.87900623704924 0.0042588091659524 COG8 essential 4.3229790888548e-14 1 4.18893661318434e-08 7.25852061027461 -2.87900623704924 0.20257553011668 11.0238840926329 28.4174618066371 0.387926415372473 0.69832841280004 -71.4201729089074 52.0460455783296 -1.37224974760896 0.170946822445463 ARHGAP19 other 1 1 1 0.387926415372473 -1.37224974760896 0.330858147322139 7.77917062610888 9.5386608128965 0.815541172780905 0.415371106072109 -20.5641000181081 25.5342007323792 -0.805355148321966 0.421214642669523 LCAT other 1 1 1 0.815541172780905 -0.805355148321966 1.89167199969226e-05 -81.8855150691962 23.9833492463759 -3.41426521492071 0.000725203145332248 326.818246874463 127.855294732003 2.55615731487308 0.0110632446477002 PTPRCAP other 0.176038996291362 1 1 -3.41426521492071 2.55615731487308 0.135249262468164 19.8057277830564 15.4551809629564 1.28149439534403 0.200950768034567 -30.212297124353 33.3707775003316 -0.905351909288082 0.365962256023098 HNRNPA1P33 other 1 1 1 1.28149439534403 -0.905351909288082 0.108358749858929 -8.39774829713183 4.47736541992486 -1.87560038315407 0.061620496640592 -26.451695544042 19.3797355246131 -1.3649151976531 0.1732386017345 PVRIG other 1 1 1 -1.87560038315407 -1.3649151976531 0.00773550774736301 14.3456347449864 4.68697613494381 3.06074414120276 0.00239481878516727 27.6385944185621 20.2870101915668 1.36237888962324 0.174036451005593 GPC2 other 1 1 1 3.06074414120276 1.36237888962324 8.25131648362433e-06 154.103968746202 31.6304227439183 4.87201736106522 1.74303820313846e-06 0.58809368197784 158.294899878154 0.00371517769953751 0.997038046099882 SIPA1 other 0.0793611619394988 1 0.0204981292689082 4.87201736106522 0.00371517769953751 6.16386733708723e-05 285.342680943701 64.9198424238617 4.39530766388339 1.5385502620352e-05 42.968054371631 242.447218376843 0.177226427505737 0.85945053262798 ERV3-1 other 0.544022931171319 1 0.170440598028259 4.39530766388339 0.177226427505737 6.63753476780748e-05 85.4809456827718 20.3732472007219 4.19574478435343 3.53513478223939e-05 -27.5056782760944 61.4517542960942 -0.4475979342032 0.654749102666312 SYNJ2BP other 0.583439306090278 1 0.381794556481855 4.19574478435343 -0.4475979342032 5.34844699470681e-07 290.916376915544 57.176697673692 5.08802342128618 6.2294387643023e-07 -193.894382529737 239.023518996993 -0.811193740864371 0.417866915924935 ARL2 essential 0.00564261157941568 1 0.00749775249671425 5.08802342128618 -0.811193740864371 0.705482236703876 0.722593813994319 1.76104149148147 0.410321856406938 0.681844446608111 3.11201164862637 3.7878054765521 0.821586976388006 0.411923695031242 GBP7 other 1 1 1 0.410321856406938 0.821586976388006 0.53326523340627 -14.1741841972286 39.9217150389637 -0.355049480799975 0.722786416368307 -96.381372835829 85.8671936972532 -1.1224469868626 0.262513910088458 RBMXL1 other 1 1 1 -0.355049480799975 -1.1224469868626 1.08867157908738e-08 105.906173311439 38.877920707901 2.72406989322132 0.00680248859477137 -249.795248068484 57.0856805075526 -4.37579522303208 1.63975198885822e-05 SRA1 other 0.000126046395426737 0.240043293648955 1 2.72406989322132 -4.37579522303208 3.12541311534522e-14 56.5547098691606 23.7670652375406 2.37954115512046 0.0179199867437978 -185.713073529944 34.2861455767303 -5.41656317460152 1.19596620321942e-07 TMEM110 other 4.23743510178505e-10 0.00180698533644422 1 2.37954115512046 -5.41656317460152 0.526909256441708 -3.34598266572966 3.27030187413295 -1.02314183659782 0.307018480420434 -6.0909176188369 6.61296099982005 -0.92105754426839 0.357718592707862 KRT8P41 other 1 1 1 -1.02314183659782 -0.92105754426839 0.000321886283437648 59.7821323219549 51.6478150055134 1.15749586532505 0.247933065556909 -385.507561434295 120.82867324706 -3.19053045170861 0.0015608828530029 DNAJC9 essential 1 1 1 1.15749586532505 -3.19053045170861 3.07261513157986e-05 79.2185025968218 17.3133801226032 4.57556537405422 6.81007124930149e-06 -15.8538326688611 85.3103852477342 -0.185837077429939 0.852690639030851 C8orf82 other 0.280560487664557 1 0.0773555993208157 4.57556537405422 -0.185837077429939 0.707325152354012 -12.2200722639535 18.8884923578971 -0.646958583692597 0.518122538246964 -27.1760007606731 37.1115253805348 -0.732279271251057 0.464534117521277 CPLX3 other 1 1 1 -0.646958583692597 -0.732279271251057 1.54480463690435e-17 1125.51510401186 154.747041620409 7.27325764826396 2.73505794189829e-12 -645.017741597029 231.077642977403 -2.79134637728716 0.00556524204713136 VDAC1 other 2.19285018208572e-13 1 3.81759387530163e-08 7.27325764826396 -2.79134637728716 2.33991457422185e-21 87.3970302213181 9.45141489633227 9.24697848734094 3.40592249383324e-18 -25.3302637669618 21.7820770267953 -1.16289478435879 0.24574137048776 ZBTB9 other 3.42633691103306e-17 1 5.01147435742623e-14 9.24697848734094 -1.16289478435879 4.34370783671441e-09 278.926616855889 53.42412601033 5.22098605416505 3.23266827327712e-07 -418.127997658422 193.017696091599 -2.16626768490695 0.0310380500807183 TMX2 essential 5.12731273045769e-05 1 0.00393932955781549 5.22098605416505 -2.16626768490695 0.00151022493181385 148.283988627059 78.3536944379898 1.89249517448616 0.0593274061129201 -339.213133519169 154.482970452328 -2.19579629085296 0.0288239680738599 HEXA other 1 1 1 1.89249517448616 -2.19579629085296 9.64967076572564e-06 221.533964299436 69.2398979437411 3.19951315467617 0.00151496654199707 -338.621369411759 181.962013094132 -1.86094538994017 0.0636717214884061 NDUFS3 other 0.0922122538372743 1 1 3.19951315467617 -1.86094538994017 0.000595307601757752 186.546562815787 67.3841598638687 2.76840377905807 0.00596248779850324 -298.985419097519 156.861228088097 -1.90605048004343 0.057542227057637 LEPROT other 1 1 1 2.76840377905807 -1.90605048004343 0.706115871518289 73.9737717437814 108.967964701944 0.678857973957019 0.497718527049437 -141.842561453067 378.864012466712 -0.374389112678074 0.708362809047737 LBH other 1 1 1 0.678857973957019 -0.374389112678074 2.04530185269332e-06 19.1584067422767 9.89831611960633 1.9355218110612 0.0538125543929339 -52.7521122563059 16.4026948787514 -3.21606374112603 0.00143328306875489 ADAT3 essential 0.0206332471238599 1 1 1.9355218110612 -3.21606374112603 1.7277505866347e-10 1783.75430581404 267.873433406152 6.65894442435992 1.20153754123225e-10 -948.358008245318 934.629687105498 -1.01468851388868 0.311020907871802 PPP1CB essential 2.1462284732e-06 1 1.63060659720629e-06 6.65894442435992 -1.01468851388868 0.163477545246107 -39.433905631845 22.2139290869975 -1.77518823785779 0.0768172770948873 -0.829509523882215 51.1774037714879 -0.0162085112325365 0.98707814627019 GPSM3 other 1 1 1 -1.77518823785779 -0.0162085112325365 0.0773710315737371 -30.4084961559179 13.8262113471806 -2.19933685319506 0.0285734520898539 -57.7200724744135 50.0762107020136 -1.1526445724475 0.249922017155421 LAT other 1 1 1 -2.19933685319506 -1.1526445724475 5.12082598444961e-20 115.273502986217 23.9523465738323 4.81261836417114 2.30580107825741e-06 -167.974491598448 33.7883504154663 -4.97137295940789 1.08898861025724e-06 NCKIPSD other 7.43185475123172e-16 0.0163097824158227 0.0269340623951248 4.81261836417114 -4.97137295940789 7.23334655398149e-10 563.523086450334 94.6108773718045 5.95621879961841 6.91474136148815e-09 -120.048341027315 211.849880719397 -0.56666702204248 0.571345249159561 ATF6B other 8.7943027403307e-06 1 8.98363197684541e-05 5.95621879961841 -0.56666702204248 9.05003369336053e-11 -67.8931083872101 36.2788917080667 -1.87142178800666 0.0621988809925038 -349.673537968891 51.8924751565186 -6.73842473141246 7.45825607140403e-11 TREX1 other 1.13315471874567e-06 1.14096401380339e-06 1 -1.87142178800666 -6.73842473141246 0.000480283725576502 3.36064269543733 1.10614022521561 3.03817058527302 0.00258331070675859 -2.19127440859762 2.62657643681622 -0.834270184519646 0.404773235348711 SEC14L1P1 other 1 1 1 3.03817058527302 -0.834270184519646 0.760923681561432 14.2543103703221 25.8935230145135 0.550497140243623 0.582363718509684 28.1241876731647 49.1683212807698 0.571998126854178 0.567726091974817 S1PR3 other 1 1 1 0.550497140243623 0.571998126854178 0.0010122671951319 183.486993554656 55.6822855097168 3.29524896248443 0.00109366811940445 -255.74494733683 193.725928144201 -1.32013793810019 0.187732482834101 SLC35F6 other 1 1 1 3.29524896248443 -1.32013793810019 1.79938120991138e-09 1426.21109977783 281.560040777459 5.06538888060856 6.89914003775534e-07 -1273.1285280441 657.900732609519 -1.93513772662073 0.0538543137439151 CLIC1 other 2.15349943202194e-05 1 0.00828172770132151 5.06538888060856 -1.93513772662073 0.0021822399620213 146.814216098619 41.819299976398 3.51068086222099 0.000511124962691014 92.4297054127039 97.7160964166622 0.945900509764358 0.344913021141537 DDAH2 other 1 1 1 3.51068086222099 0.945900509764358 4.00731745476228e-08 72.8652696788587 13.7465852514019 5.3006087218226 2.20052577881173e-07 -76.032786984616 60.6369675863993 -1.25390153912759 0.210825584069541 ZNF337-AS1 other 0.000451344164929875 1 0.0027022456563808 5.3006087218226 -1.25390153912759 1.04474300110761e-08 12.2019586599128 2.49890293437854 4.88292622016044 1.65337508296706e-06 -10.2538422862505 5.83900352730498 -1.75609455248662 0.0800288748178143 ATP6V1G2 other 0.000121106608688394 1 0.0194833719776838 4.88292622016044 -1.75609455248662 7.87800171535421e-06 90.7804653013965 18.4783828032057 4.91279276266793 1.43546630031121e-06 46.8452131123814 48.0189639140816 0.975556515467506 0.330021172441341 ZNF134 other 0.0759251899198003 1 0.0169743890011801 4.91279276266793 0.975556515467506 9.35636526351103e-18 146.194756102897 17.4384493005516 8.38347226770173 1.65454061721066e-15 -34.4742157914172 40.7522693449829 -0.845945915295669 0.398215037125643 GTF2H4 essential 1.33094295873444e-13 1 2.39345845685694e-11 8.38347226770173 -0.845945915295669 1.56152847130625e-24 382.798538094963 35.4404372262328 10.8011798966074 2.19720664217225e-23 -173.429070147088 138.923974822032 -1.24837394243332 0.2128095951139 DDX47 other 2.32292975391518e-20 1 3.29778744923634e-19 10.8011798966074 -1.24837394243332 0.0287752068602543 16.9271625753262 8.55267651610139 1.97916553297191 0.0486569136149292 -38.3491889198401 27.2293262337441 -1.408378179858 0.159992976677469 ZNF845 other 1 1 1 1.97916553297191 -1.408378179858 0.372806960365277 0.855286784538049 2.49297623271591 0.3430785955012 0.731766020015139 -10.2125282492394 8.07168923174321 -1.26522812710343 0.206715869641468 ZNF321P other 1 1 1 0.3430785955012 -1.26522812710343 0.398871659857316 373.719791767242 280.193953899942 1.33378963594874 0.183224311238229 74.0467729607831 908.794229485307 0.0814780404170471 0.935112884421475 EMP2 other 1 1 1 1.33378963594874 0.0814780404170471 3.55745470512665e-06 557.28999450063 110.051454774195 5.0639039315208 6.94909595265544e-07 -94.7317316393895 210.065991309602 -0.450961771816604 0.652322527019604 KCTD11 other 0.0352614910372153 1 0.00833822023359127 5.0639039315208 -0.450961771816604 0.0420129387205852 3.24860714593067 1.70191990792017 1.90878967383408 0.0571949608465448 -11.1524702814145 8.0478915056694 -1.38576300060184 0.166796479738772 C8orf44 other 1 1 1 1.90878967383408 -1.38576300060184 0.22219719434481 -553.281221316172 333.195528726042 -1.66053015006419 0.0977873321392532 -125.217368183625 754.644079959387 -0.16592904060198 0.868317577382435 UBD other 1 1 1 -1.66053015006419 -0.16592904060198 0.0222553701816789 15.7307157946486 7.79852263080465 2.01714049434328 0.0445155498385514 -25.6001464149706 18.7084260898452 -1.36837520655285 0.172154616428461 PPM1N other 1 1 1 2.01714049434328 -1.36837520655285 0.174293960626672 0.77466629359946 2.97712061814844 0.26020655289447 0.794871797245748 -7.96984040273495 5.22560852911705 -1.52515068021783 0.128209210920257 SLC23A3 other 1 1 1 0.26020655289447 -1.52515068021783 5.94007646753546e-06 345.371485208588 103.740845513585 3.32917553832123 0.000972698779734857 -792.788414609143 282.457917417481 -2.80674877821668 0.00531120455398278 LTB4R other 0.0578622848702629 1 1 3.32917553832123 -2.80674877821668 1.73285998615665e-06 99.4508414648669 32.9091842629679 3.02197832283485 0.00271395258516421 -308.142468221182 89.6026980000739 -3.4389864936983 0.000661206426605313 LTB4R2 other 0.0176007515404031 1 1 3.02197832283485 -3.4389864936983 0.000125195512336976 267.598380654314 69.0356748106167 3.87623328646252 0.000128731253455254 -148.282618036338 198.397170369187 -0.747402887654125 0.455369249278106 DNASE1 other 1 1 1 3.87623328646252 -0.747402887654125 0.0437276702102173 17.1953608632001 8.70100211838496 1.97625062369158 0.0489848999801232 -24.3083119761689 23.6904463775773 -1.02608079175648 0.305628500806419 MDP1 other 1 1 1 1.97625062369158 -1.02608079175648 5.78045840548755e-12 499.627282523787 84.4482460754646 5.91637252095574 8.4587530223878e-09 -694.730351285213 229.929451586272 -3.02149353417887 0.00271817983391456 IRF9 other 7.48164731422254e-08 1 0.000109515475380855 5.91637252095574 -3.02149353417887 9.58426861626703e-20 125.762273489481 13.5395828794022 9.28848950589187 2.76172567602693e-18 -86.739408844131 42.9484178249951 -2.01961825922375 0.0442776079916281 GALT other 1.38876052249709e-15 1 4.06526019511165e-14 9.28848950589187 -2.01961825922375 0.358154867877217 10.1816625459515 11.9017129757033 0.855478750557737 0.392926234546139 -13.5592407039916 23.6637407306502 -0.572996503736584 0.567049468490125 HBE1 other 1 1 1 0.855478750557737 -0.572996503736584 0.413221850189143 -72.6578097679756 69.3672069299594 -1.04743744174879 0.295716475714517 -121.784890878356 103.747583586471 -1.17385761353036 0.241356011966749 ITGA1 other 1 1 1 -1.04743744174879 -1.17385761353036 0.00121174242492518 56.6386008415992 17.1945755613391 3.29398074640165 0.00109880817018077 -42.2627460925757 52.0347978512331 -0.812201600425247 0.417281635650273 NUDT19 other 1 1 1 3.29398074640165 -0.812201600425247 0.0930842085405118 6.40665701330611 3.17753905360624 2.01623234371741 0.0446351356087167 -0.964121464900597 7.42831993390648 -0.129789975859801 0.89681649751793 ZNF726 other 1 1 1 2.01623234371741 -0.129789975859801 6.24767844138285e-05 675.519842434426 168.513731891811 4.00869314833122 7.60205296887639e-05 -571.536426913953 319.365613290155 -1.78959914007615 0.0744638766953477 TAX1BP3 other 0.550670377823484 1 0.797835459083577 4.00869314833122 -1.78959914007615 1.25195706953504e-14 323.331231641853 46.0431117765557 7.02235837601418 1.31417190827428e-11 -349.698984878224 124.365238526957 -2.81187081712085 0.00522940056463743 AP1G2 other 1.71079933551964e-10 1 1.8144771537543e-07 7.02235837601418 -2.81187081712085 0.95661271652592 12.5442534865182 60.0148324113914 0.209019220457528 0.834567062087966 -17.6430059247455 135.074393241173 -0.130616954860158 0.896160918423631 ZNF90 other 1 1 1 0.209019220457528 -0.130616954860158 6.28769941119318e-10 103.8968782522 20.4362770373945 5.08394352171331 6.3338247456057e-07 -156.808382822269 49.9921549285096 -3.13665980285328 0.00186913165178854 NAXD other 7.66156173253889e-06 1 0.00761959116896365 5.08394352171331 -3.13665980285328 0.000234127627618773 3.1984004671797 8.2632496810583 0.387063273001581 0.698967458697476 -74.3696633369724 19.4673827684416 -3.82021888723185 0.000160246670471639 MEF2B other 1 1 1 0.387063273001581 -3.82021888723185 1.64036620482915e-05 50.6378364612311 26.5015365595728 1.91075096145472 0.0569300138724356 -172.199233464494 52.9950785681839 -3.24934386582597 0.00127967317823182 GANC other 0.153685909730443 1 1 1.91075096145472 -3.24934386582597 1.87918355806601e-05 34.5816073642394 21.8488614073991 1.58276473631382 0.114465988898747 -121.624766961886 37.2132953562532 -3.26831488040871 0.00119988445385209 TTLL3 other 0.174951989255945 1 1 1.58276473631382 -3.26831488040871 0.000645493268809476 -0.60945396563059 83.650513626107 -0.00728571695751527 0.994191444451028 -623.240578658214 186.169504988288 -3.34770497830685 0.000912321479743088 REPIN1 other 1 1 1 -0.00728571695751527 -3.34770497830685 0.243466513058055 13.7817682532846 8.29012716586433 1.66243146547049 0.0974209950806973 12.5375151683888 20.1405102152955 0.622502361378477 0.534061950245446 ZNF891 other 1 1 1 1.66243146547049 0.622502361378477 3.29442862323379e-07 91.9253042176437 27.9193239626497 3.29253331279156 0.0011046525040725 -224.372467594904 65.8287126588955 -3.40842861013452 0.000737477122276161 SMIM7 other 0.00353228636983127 1 1 3.29253331279156 -3.40842861013452 0.454043680953855 26.8251793790147 21.4009762823123 1.25345587159898 0.210954872901775 12.5911933531178 56.5920929061151 0.222490328710873 0.824074139193504 UCA1 other 1 1 1 1.25345587159898 0.222490328710873 9.91435013861824e-10 158.652276099123 42.7721033058319 3.70924653774253 0.000245007542000149 -159.142821731275 78.4755349706306 -2.02792910925467 0.0433956698214423 FBXO16 other 1.19839812855333e-05 1 1 3.70924653774253 -2.02792910925467 0.0360541138013517 126.052429072663 52.3311983673157 2.40874340747738 0.0165723302278007 62.9698850772033 97.5360347934492 0.645606367026852 0.518996967429167 TSPAN4 other 1 1 1 2.40874340747738 0.645606367026852 5.42898573395362e-16 2235.65036825942 256.023805850399 8.73219722999418 1.52761364752339e-16 -210.875493717163 1467.30808284577 -0.143715894557182 0.885817301520496 CPNE1 other 7.57017770742493e-12 1 2.22573308444157e-12 8.73219722999418 -0.143715894557182 0.00992580644449256 67.368051948052 22.1150331276195 3.04625598158911 0.00250981723112498 51.7348423005566 51.0072962477486 1.01426356828 0.311223263763218 ARL16 other 1 1 1 3.04625598158911 1.01426356828 3.93065661563266e-15 17.5084233291227 5.22338375984321 3.35193126412145 0.000899292128214096 -60.4396454926982 11.6669121600973 -5.1804320340571 3.93859814600172e-07 PAXIP1-AS2 other 5.41172802840305e-11 0.00592877178917639 1 3.35193126412145 -5.1804320340571 9.48753346546689e-09 138.73776529191 28.8804487063293 4.80386460413631 2.40497497648556e-06 -108.409414174083 64.6747344690514 -1.67622511424396 0.0946800085940072 LYRM4 essential 0.000110264113935656 1 0.028068462950563 4.80386460413631 -1.67622511424396 5.17373773126275e-06 56.8747779454462 16.7429602225923 3.39693681340183 0.000768008639395433 -131.916983830608 41.9133674670938 -3.14737258785459 0.00180348998783266 MYCBP other 0.0506405449135998 1 1 3.39693681340183 -3.14737258785459 0.650904517449027 12.268691216928 50.7764896326723 0.241621492656981 0.809228224548199 -76.426184804896 111.735573044991 -0.683991523219939 0.494475531249227 TMEM213 other 1 1 1 0.241621492656981 -0.683991523219939 0.941898410721784 2.02762438101164 8.45797706243109 0.239729236204483 0.810694133081552 -4.11567994877882 20.3986964406595 -0.201761909676506 0.840231461049597 PRCD other 1 1 1 0.239729236204483 -0.201761909676506 0.165453440144728 1.80575254288989 0.961495770256548 1.87806602873362 0.0612813152916991 1.78783542487085 5.86461111038491 0.304851488226558 0.760677439960899 LINC00887 other 1 1 1 1.87806602873362 0.304851488226558 2.19330737487812e-31 475.200745264938 36.850881116358 12.8952342757959 6.83132326530503e-31 617.902063957145 242.366248232994 2.54945591006194 0.0112581944632212 ALG3 other 3.32110602704045e-27 1 1.03890764218759e-26 12.8952342757959 2.54945591006194 0.0665967749126618 12.1270500067057 7.11125734573712 1.70533133834276 0.0891091865320897 29.5888155704381 16.5060769227748 1.7926013376087 0.073987063877617 AMZ2P1 other 1 1 1 1.70533133834276 1.7926013376087 0.721885565565531 4.42068265152799 7.83618750407392 0.564136915972179 0.573066251160344 -6.37867556780114 16.7368156554076 -0.381116438104535 0.703376236344349 ZNF788 other 1 1 1 0.564136915972179 -0.381116438104535 0.00393642892003438 68.9564127057276 24.5342196482798 2.81062180473966 0.00525118604197269 -74.4287903429671 58.2740017674336 -1.27722119788522 0.202455905015421 SH3D21 other 1 1 1 2.81062180473966 -1.27722119788522 0.489763283897016 0.701110161881486 4.44661650161264 0.157672729732194 0.874815075185722 -10.2761568080728 9.54446799980562 -1.07666103634923 0.282450411928516 C19orf38 other 1 1 1 0.157672729732194 -1.07666103634923 0.306703714055488 2.32852750328683 1.73216217634558 1.34428954464266 0.179822073284191 -2.41362441155264 4.11867309402766 -0.586019904093033 0.558281790530195 C17orf67 other 1 1 1 1.34428954464266 -0.586019904093033 0.000972424707072287 172.443458203982 55.8753518388281 3.08621695486399 0.00220431063232599 -314.8820727209 232.465740068144 -1.35453109188733 0.176522607037933 FIS1 other 1 1 1 3.08621695486399 -1.35453109188733 0.104802757879548 17.0046893435575 8.10356709762285 2.09842025600625 0.0366565787969401 -12.0271577741908 26.7151368630134 -0.450200118227439 0.652872907933902 ANKRD36BP1 other 1 1 1 2.09842025600625 -0.450200118227439 0.625296221517901 38.4679263442907 40.6002379206156 0.947480318206653 0.344115779085925 50.5246541439268 90.9348822878213 0.555613565144444 0.578866957768835 SNURF other 1 1 1 0.947480318206653 0.555613565144444 0.446641243763827 9.47092724814633 8.10031803782781 1.16920436999114 0.243194213416785 16.6637545153045 22.82063586427 0.730205530398681 0.465800462261978 ANG other 1 1 1 1.16920436999114 0.730205530398681 0.585631323243543 2.98547964156406 3.70191711283908 0.806468527134156 0.420597036659219 6.98580108812886 7.48330705858174 0.933517899698858 0.351286255519599 SCART1 other 1 1 1 0.806468527134156 0.933517899698858 0.719585129076743 -33.3084872264936 49.2411965925126 -0.676435373862509 0.499252887627888 -69.0111478122877 99.7404724466173 -0.691907167867323 0.489497343643482 NPS other 1 1 1 -0.676435373862509 -0.691907167867323 0.202848453731719 -20.8942106628815 14.2886133362245 -1.46229799709889 0.144650229337986 -3.44082680830935 26.0560891577642 -0.132054614469419 0.895024870266848 COLCA2 other 1 1 1 -1.46229799709889 -0.132054614469419 0.0245140660500973 13.0442858301565 7.38064842730144 1.76736311973687 0.0781234677001139 -40.541564521015 25.8858805952748 -1.56616516760166 0.118301372051482 APTR other 1 1 1 1.76736311973687 -1.56616516760166 1.21647744349201e-11 20.5906588245036 3.05814951146308 6.73304517889728 7.70388778637349e-11 -19.4731951507663 13.2368308521652 -1.47113726603078 0.142236658883587 SPDYE3 other 1.561348798722e-07 1 1.04873024435902e-06 6.73304517889728 -1.47113726603078 0.279044266930939 3.14146198811789 1.97295349388588 1.59226357734897 0.112312790144165 1.58551864105969 8.53969094050656 0.185664639634562 0.852825389543153 MBLAC1 other 1 1 1 1.59226357734897 0.185664639634562 0.856192655607242 -0.0711457213511994 18.6295901283838 -0.00381896331915552 0.996955317671556 -43.7167235810838 80.0704297228566 -0.545978380937858 0.585464814696722 AZGP1P1 other 1 1 1 -0.00381896331915552 -0.545978380937858 0.686639051126486 2.74424302907531 8.3004722885985 0.330612877636468 0.741156016889458 27.9587963238799 33.8124398799518 0.826878995516006 0.408929585501565 FOXI3 other 1 1 1 0.330612877636468 0.826878995516006 2.66074846484688e-15 5.81024308375293 0.801647401604924 7.24787864604892 3.19451910610951e-12 -3.03666638004885 2.20380524734364 -1.37791957057417 0.169190900413937 VAC14-AS1 other 3.67449362995354e-11 1 4.45220127818482e-08 7.24787864604892 -1.37791957057417 1.74115033044508e-05 112.441627493268 145.455428451474 0.773031496248211 0.440074363066278 -912.043722980292 220.329392043692 -4.13945554208868 4.4569857566591e-05 NEURL1B other 0.16262344086357 0.64403444183724 1 0.773031496248211 -4.13945554208868 7.73424970624413e-13 41.5577486008834 12.139135804594 3.42345198783888 0.000698744438270635 -88.0257317867667 22.4512282364526 -3.92075350442721 0.000108017049111392 HAUS3 essential 1.02146235870366e-08 1 1 3.42345198783888 -3.92075350442721 0.000439443154715511 9.33703201740752 2.82140945885483 3.30935022143057 0.00104424743974535 0.816287224121881 6.69037616549989 0.122009167187222 0.90297005370473 VSTM5 other 1 1 1 3.30935022143057 0.122009167187222 0.00199807196430701 32.3700308520835 26.6932933786214 1.21266530858304 0.22615229367922 -126.560946580736 50.3743770558435 -2.51240717955548 0.0124826150455854 BBIP1 other 1 1 1 1.21266530858304 -2.51240717955548 0.789685112610297 2.36678763010924 20.5945419679893 0.114923052612096 0.908578189653078 -21.267900934985 37.8993286572936 -0.561168276285339 0.575075575327535 AS3MT other 1 1 1 0.114923052612096 -0.561168276285339 0.430401441670296 8.72525269401054 9.84497029212547 0.886265009960413 0.376140277449133 22.8814155125899 18.2642686179023 1.25279670329432 0.211194411879091 PLIN5 other 1 1 1 0.886265009960413 1.25279670329432 0.747955824497332 -10.6123359062218 43.6308633096105 -0.243230023456452 0.807983051809455 79.4015987609333 113.04599231354 0.702383137481851 0.482950854222897 KRT42P other 1 1 1 -0.243230023456452 0.702383137481851 1.34353464150409e-37 447.375662429772 37.3549214778378 11.9763513007301 1.66354967952933e-27 -383.818560257389 130.028957014773 -2.95179296265356 0.00339583612666309 PPME1 other 2.04875597482959e-33 1 2.51761608499969e-23 11.9763513007301 -2.95179296265356 3.49500116598648e-14 604.586675890562 81.8224352282602 7.3890085794189 1.40043785469875e-12 -42.1962883623946 284.414252807879 -0.148362073791351 0.882154113706164 STARD10 other 4.73397907932868e-10 1 1.96229352200389e-08 7.3890085794189 -0.148362073791351 0.0080770214126685 123.679093440892 39.6779738629514 3.11707180079513 0.00199441861866923 78.2839287429181 119.174269259391 0.656886165356112 0.51173222251157 MEG3 other 1 1 1 3.11707180079513 0.656886165356112 0.0323780489015087 -0.971999988290663 4.04589110486333 -0.240243734469837 0.810296108095014 -20.6156358037161 8.25880726396855 -2.49620013457122 0.0130591785720983 NUTM2D other 1 1 1 -0.240243734469837 -2.49620013457122 0.0744775231209185 -22.2456355364671 10.0975433422451 -2.2030740332055 0.0283132163293982 -3.42501885353078 19.9171284913944 -0.171963486353498 0.8635766591761 CPEB1 other 1 1 1 -2.2030740332055 -0.171963486353498 0.311923930474191 11.0565418854749 9.86392919325731 1.12090645308289 0.263170801957199 -34.2539000175594 39.0527278267852 -0.877119267301618 0.381081930983187 EML6 other 1 1 1 1.12090645308289 -0.877119267301618 0.0508629784788583 41.2303012652496 16.9737713442465 2.42905954304759 0.0157193670223888 19.3881869998751 58.7140723725354 0.330213630505116 0.74146674334725 SLC6A10P other 1 1 1 2.42905954304759 0.330213630505116 1.99826317110954e-06 163.766691052693 56.0706181235534 2.92072205610125 0.00374030331301688 -384.187135799811 131.699852030587 -2.91714174219864 0.00378236524515786 ZSWIM8 other 0.0201864545545485 1 1 2.92072205610125 -2.91714174219864 0.76403390414916 -1.73721985356704 4.83212944155415 -0.359514345503191 0.7194474752864 -8.09769643469253 11.1471577421564 -0.72643597785188 0.468102564127461 C10orf105 other 1 1 1 -0.359514345503191 -0.72643597785188 0.0115013332302728 -17.4661298680062 5.81067594295803 -3.00586885922859 0.00285837308423369 -12.9928285672933 19.9018699210638 -0.652844613035176 0.514326662748439 ARHGEF33 other 1 1 1 -3.00586885922859 -0.652844613035176 4.74038042374877e-20 293.31213805263 63.6967595146799 4.60482040668068 5.98457298851788e-06 -470.268048044488 90.6446093046915 -5.18804208713323 3.79968713049004e-07 IFRD2 other 6.88398045136796e-16 0.00572042897495275 0.0681942092041612 4.60482040668068 -5.18804208713323 0.922248158306332 28.200068980155 72.0054518450017 0.39163796987009 0.695587213850644 37.9565586515881 250.381488851936 0.151594907537409 0.879602274930959 CAPN14 other 1 1 1 0.39163796987009 0.151594907537409 1.61914059915432e-10 381.106262131769 66.8547295075744 5.70051311162049 2.72740077400338e-08 -389.989015955128 183.662535359402 -2.12339993669353 0.0344922493448165 TOMM6 other 2.01291559286865e-06 1 0.000347307214561591 5.70051311162049 -2.12339993669353 6.30809134106252e-11 635.49722882241 117.748448360771 5.39707518586826 1.34002498624477e-07 -1253.05715266571 431.658884654307 -2.90288743545548 0.00395998487764873 HNRNPUL2 other 7.94945670800699e-07 1 0.00166055896295452 5.39707518586826 -2.90288743545548 0.0468627345115464 6.21310900806167 5.18234980573639 1.19889803679102 0.231474466011758 -33.1256572029444 18.998189514809 -1.74362178970387 0.0822068885317794 METTL12 other 1 1 1 1.19889803679102 -1.74362178970387 0.0685932587256348 9.95797876013318 4.34353259047917 2.29259906601383 0.0225237285697233 14.3506861296396 17.9989930795032 0.797304941795987 0.42586886381983 SEPT7P2 other 1 1 1 2.29259906601383 0.797304941795987 0.615094071903577 42.6491532263148 43.2647963717555 0.985770344551014 0.324990567836084 25.4218988411242 173.503897451209 0.146520621234304 0.883602673391067 POLR2J4 other 1 1 1 0.985770344551014 0.146520621234304 0.0572712123742371 13.0819198610709 6.68081586614278 1.95813207895279 0.051088563458405 59.6647011442025 39.3157942054043 1.51757588394338 0.130114830818575 FER1L6 other 1 1 1 1.95813207895279 1.51757588394338 0.939863262648096 197.893697373509 562.098303157895 0.352062435096731 0.725023901471618 36.7054215024853 1032.70357734688 0.0355430370414568 0.971668959822249 KRT16P3 other 1 1 1 0.352062435096731 0.0355430370414568 0.466798616259571 1.76862188061334 1.84587458693125 0.958148453386345 0.338720392472288 4.4557985706907 6.02974804124262 0.738969280343668 0.460474180073156 LINC01347 other 1 1 1 0.958148453386345 0.738969280343668 0.508655663113766 4.22160430364764 3.66388787624369 1.15221984030137 0.25009349353337 0.131015932553185 15.1289226081324 0.00865996448965631 0.993095847560898 APOC1P1 other 1 1 1 1.15221984030137 0.00865996448965631 0.0132848693251688 25.9768993362652 8.84906779220301 2.93555207692653 0.00357135838810707 -3.84546925497347 16.4984585331559 -0.233080517628085 0.815848367386141 EVPLL other 1 1 1 2.93555207692653 -0.233080517628085 0.0380807916612546 15.2166190644599 34.7130331529229 0.438354637505325 0.661430649531188 334.414123942865 130.571278789289 2.56116143644829 0.0108993113713338 SMTNL1 other 1 1 1 0.438354637505325 2.56116143644829 1.08840810718734e-07 21.0629923708076 3.86253849428767 5.45314756136613 9.99443849719285e-08 -8.46978634148347 11.857569148804 -0.714293649498791 0.475572911069813 LINC01588 other 0.00119844616682399 1 0.00124460742605543 5.45314756136613 -0.714293649498791 0.802439287393415 2.67723420647149 4.39249028124457 0.609502590797519 0.542623866146173 4.74223747490313 9.90721873818073 0.478664860464558 0.632503954292932 HLA-F-AS1 other 1 1 1 0.609502590797519 0.478664860464558 6.65175648131533e-16 89.6858876854836 10.4276404407995 8.60078444348501 3.67215380729028e-16 -29.4282536809948 21.8245671260136 -1.34840033761394 0.178489232479095 ZSWIM7 other 9.26124054893533e-12 1 5.33343618970841e-12 8.60078444348501 -1.34840033761394 1.69734154298852e-06 38.9514415545671 65.5008070853627 0.594671169529322 0.552483526727607 -411.315840937912 90.0993758354197 -4.56513529782096 7.12802355356263e-06 ARHGEF28 other 0.0172534767844783 0.105345060098102 1 0.594671169529322 -4.56513529782096 7.20996529797211e-06 17.7658944395088 3.67742582773452 4.83106805459446 2.11257796703156e-06 -3.5584141194235 15.6485195314936 -0.227396215486198 0.820261330208805 ISPD other 0.0696915245701984 1 0.0247256125261373 4.83106805459446 -0.227396215486198 6.97612063753366e-07 40.244952723288 7.50708825934331 5.36092707757887 1.60390417192421e-07 -4.57420658968466 35.0329843705585 -0.130568567647602 0.896199952865446 COL28A1 other 0.00729841741098772 1 0.00198082165232639 5.36092707757887 -0.130568567647602 1.8783403187875e-47 2063.5511158252 118.473940087082 17.4177638922823 3.21540976743492e-48 249.891038325553 665.316318476044 0.375597338267527 0.707465901972733 PHB2 essential 2.87667819822306e-43 1 4.92697238664053e-44 17.4177638922823 0.375597338267527 1.3510440153283e-06 62.2355171384832 11.9589798259745 5.20408245888245 3.49722222128171e-07 -19.3653417744028 66.4362784035457 -0.291487455946498 0.770867985480586 CD27-AS1 other 0.0138576584652223 1 0.00425507027663346 5.20408245888245 -0.291487455946498 4.27640594920075e-18 164.942028931781 18.6803176754544 8.82972290929034 7.02456210726442e-17 -113.893010270288 35.6569520914023 -3.19413195997057 0.00154213965807961 NEURL4 other 6.10243128950947e-14 1 1.02502410269202e-12 8.82972290929034 -3.19413195997057 0.00351522236235285 49.9310110895606 14.8741841075497 3.35689075303412 0.000883243765099562 17.9985971406993 28.3918121381036 0.633936187417359 0.526575343149794 ALOX12-AS1 other 1 1 1 3.35689075303412 0.633936187417359 0.0944333721011235 23.150243531631 15.0866559814598 1.53448474997247 0.125930373674192 -90.9894305395232 69.8372383214613 -1.30287841739529 0.193583234067643 UBXN2B other 1 1 1 1.53448474997247 -1.30287841739529 0.319888572239213 -294.361769179659 232.736862361644 -1.26478361095312 0.206869226540688 -612.528719118532 433.489052466716 -1.41302004198956 0.158621744770346 MUC5AC other 1 1 1 -1.26478361095312 -1.41302004198956 8.79736873574933e-36 46.7456412530616 3.61162085067026 12.9431197752628 6.53900514520376e-31 -42.7340361658289 11.5827877077129 -3.68944309817339 0.000265513907505322 MSMP other 1.33913546895576e-31 1 9.94517292534039e-27 12.9431197752628 -3.68944309817339 2.94556555701011e-16 281.484676230307 34.1183962874932 8.25023174765957 4.36261498131543e-15 -113.76482070494 111.503054639194 -1.0202843417435 0.308376577316946 PEX26 other 4.11937343147864e-12 1 6.29045454155872e-11 8.25023174765957 -1.0202843417435 0.147571395540444 11.1178816952233 8.68470220747434 1.28016844212054 0.201416022526269 -66.0649284657564 49.3710665490218 -1.33813046959718 0.181806952843929 UBE2QL1 other 1 1 1 1.28016844212054 -1.33813046959718 9.46451075569943e-10 85.9036692354626 14.9292576952496 5.75404825805886 2.03892154045284e-08 -87.5466107245647 54.6302428573384 -1.60253013981988 0.110025021882681 FASTKD5 essential 1.14520580143963e-05 1 0.000260941178747154 5.75404825805886 -1.60253013981988 0.338984173074569 29.2406200007694 39.8581402258805 0.733617269522853 0.463720841712114 -114.510827199112 107.675754174694 -1.06347829255348 0.28836947195325 DHRS4-AS1 other 1 1 1 0.733617269522853 -1.06347829255348 6.24312395087077e-06 65.525092946668 20.1917969690422 3.24513430117835 0.00129812310985039 -160.475668671997 55.381072615797 -2.89766270482494 0.0040188687454368 HOMEZ other 0.060676921678513 1 1 3.24513430117835 -2.89766270482494 0.145884430998819 1.43728720454105 0.861543160161484 1.66827069263906 0.0962401420914299 -1.44676497827927 2.36299841899656 -0.612258123682382 0.540801789964623 RNF212B other 1 1 1 1.66827069263906 -0.612258123682382 3.10398405577942e-11 155.843829651061 26.2040610380589 5.9473159303328 7.13772740325379e-09 -217.547439750581 95.887836326463 -2.2687699304207 0.0239479846714825 VPS16 other 3.94485333649006e-07 1 9.26691148764439e-05 5.9473159303328 -2.2687699304207 0.000915056939716188 80.5848976978969 74.0562498807889 1.08815795868164 0.277351992724784 -334.299996126465 136.614007830608 -2.44704039823627 0.014946029384937 MYL5 other 1 1 1 1.08815795868164 -2.44704039823627 2.18039043655474e-17 65.7657893137196 16.9104664489442 3.88905826532217 0.00012270212477962 -105.426397584746 25.8254904059802 -4.08226120501215 5.65527670568239e-05 ZNF407 other 3.08852305337979e-13 0.814133634550037 1 3.88905826532217 -4.08226120501215 5.26249986588711e-20 129.463950746692 20.6196182483186 6.27867835318674 1.11917840189648e-09 -166.903730086166 34.7489892804779 -4.80312473951388 2.41012404483392e-06 MCM3AP-AS1 other 7.63430855544242e-16 0.0359277191363393 1.48783576748118e-05 6.27867835318674 -4.80312473951388 0.000163780626567818 90.5367597747835 25.7249973012136 3.51940794063805 0.00049521066867251 -179.637390140309 120.340971679159 -1.49273674322027 0.136491358329145 NPEPL1 other 1 1 1 3.51940794063805 -1.49273674322027 0.00101377405712807 3.65724690276313 22.6135868375266 0.161727855427783 0.871622874096627 -124.043923373381 36.851521311948 -3.36604620263435 0.000856023390674647 AATBC other 1 1 1 0.161727855427783 -3.36604620263435 0.985484254964376 0.899203392914834 8.93251597329285 0.100666306738588 0.919878399499972 2.85847455004386 16.7183071606071 0.170978707508091 0.864348567816511 HMX1 other 1 1 1 0.100666306738588 0.170978707508091 0.410177578531559 5.60340607701365 4.68211697182684 1.19676763966607 0.232285786441597 8.89935876977707 10.4854446357986 0.848734515214885 0.396665472526358 GCGR other 1 1 1 1.19676763966607 0.848734515214885 0.000494399010419669 61.8020993195163 17.291468992475 3.57413816873579 0.000405521195308626 -13.8569387279803 34.9686747158114 -0.396267197444424 0.692172024598762 RSC1A1 other 1 1 1 3.57413816873579 -0.396267197444424 0.000100107973625403 40.7630770927947 14.300005765281 2.85056368241218 0.00464746050555711 -80.584413399352 31.2717624504317 -2.57690667505821 0.0104164965682318 TMEM242 other 0.862530300756472 1 1 2.85056368241218 -2.57690667505821 8.66901486471038e-07 77.2689729175825 31.3186500162101 2.46718721520848 0.0141427415560593 -198.405182884515 59.7816680827352 -3.31882982271306 0.00100853740027214 TMEM167B other 0.00901664236078527 1 1 2.46718721520848 -3.31882982271306 0.00861447844136301 13.7036797934151 5.16411176109526 2.65363733927182 0.00838307079651292 30.1563912201422 19.8565913739786 1.51870936215473 0.129878373249208 FAM72D other 1 1 1 2.65363733927182 1.51870936215473 6.69061718259703e-05 75.3175202220652 27.3062670892465 2.7582503304425 0.00614634970081845 -144.743818053114 59.427817736174 -2.43562398161236 0.0154134126763788 TNFRSF25 other 0.587770719491149 1 1 2.7582503304425 -2.43562398161236 0.0001034842547808 21.0752115060389 5.87381000033614 3.58799680357941 0.000385705544776917 -17.960170447563 13.1373849879214 -1.36710391482595 0.172558335349698 SLC35E2 other 0.889654138350536 1 1 3.58799680357941 -1.36710391482595 0.0162910166935197 27.7955850246622 10.2699226544533 2.70650383258821 0.00717021407103841 -36.7515328613691 33.1085223086432 -1.11003241155752 0.267831712131059 LINC01139 other 1 1 1 2.70650383258821 -1.11003241155752 0.000383185758949424 149.361709660169 37.5376220039392 3.97898699189031 8.57143120028925e-05 -85.831634798002 128.97166391046 -0.66550769522204 0.506206723516224 TSTD1 other 1 1 0.895114560246206 3.97898699189031 -0.66550769522204 0.891812997368338 -146.17611065726 324.869724423633 -0.449953010907983 0.653051855172688 -243.057822502784 1454.72189086017 -0.16708198593139 0.867412069662246 RPTN other 1 1 1 -0.449953010907983 -0.16708198593139 0.00610158852785904 4.96686954814462 3.32474729264522 1.49390889320581 0.136187886124115 -11.1767579165848 6.07577702524381 -1.83956025215332 0.0667619082343878 LINC01356 other 1 1 1 1.49390889320581 -1.83956025215332 0.00579688164683949 -24.5649211997965 9.65353359813343 -2.54465589725055 0.0114094206354731 -58.8084337216241 23.1323416751176 -2.54226029286441 0.0114863240607247 CYB5RL other 1 1 1 -2.54465589725055 -2.54226029286441 0.000699145534713987 14.6562039313833 7.63782707527798 1.9188970615507 0.0558866757128942 -41.4145681676865 16.0831924607984 -2.57502161145129 0.0104722544261324 C1orf167 other 1 1 1 1.9188970615507 -2.57502161145129 0.0667772767000792 8.75311285063763 5.2385083031365 1.67091705197771 0.095724971114539 -13.0441026840375 11.7642643423166 -1.10879034204606 0.268361131434753 MMP23A other 1 1 1 1.67091705197771 -1.10879034204606 3.43546741995765e-05 21.8221734848143 8.21738776657223 2.6556095567968 0.00831921149495104 -54.1334160459424 18.6931712982694 -2.89589257928397 0.00404521592185915 ATAD3C other 0.311837377709556 1 1 2.6556095567968 -2.89589257928397 0.537508919219208 8.06785576571324 17.9893851369037 0.448478683641206 0.654111286048547 -40.7245371487797 43.7813785545405 -0.930179416302464 0.352979369418748 KRT19P2 other 1 1 1 0.448478683641206 -0.930179416302464 0.32794266377563 -168.825399657942 317.441485551579 -0.531831557443083 0.595213997340587 -1098.92083875163 735.92129586894 -1.49325864724987 0.136360988621528 IFI30 other 1 1 1 -0.531831557443083 -1.49325864724987 0.326346596300236 4.85443679654843 3.32084045971275 1.4618097001168 0.144796602725253 2.96611093173864 6.53187418860821 0.454097988738306 0.650073019667272 CCDC7 other 1 1 1 1.4618097001168 0.454097988738306 3.59018669341559e-06 80.3334626543417 22.2732232890115 3.60672820507189 0.000359607031309361 -65.6937601207745 33.5641536989725 -1.95725954272416 0.0511860169350565 FNIP1 other 0.0355607991982814 1 1 3.60672820507189 -1.95725954272416 0.356565396698771 -6.61184391603359 5.05860175942962 -1.30704970078117 0.192161406453469 -14.365337519723 18.9416661536211 -0.758398833725448 0.448786591993983 SP9 other 1 1 1 -1.30704970078117 -0.758398833725448 0.824129518457266 3.82012261008632 18.248553520184 0.209338378839782 0.834317296405922 -21.6431173691116 48.3828325324932 -0.447330514487269 0.654939076516767 CKLF other 1 1 1 0.209338378839782 -0.447330514487269 0.152377680172822 32.0284862482096 18.3318460030956 1.74715008203763 0.0815736289160687 -19.3769508602899 53.9561271245263 -0.359124197620217 0.719739766803962 PAM16 essential 1 1 1 1.74715008203763 -0.359124197620217 3.9692814702831e-06 313.749057768947 67.1287478039938 4.67384046377639 4.37260341275755e-06 11.7479118122658 125.863926859337 0.0933381955053341 0.925693666960428 TENM3 other 0.0392204702078673 1 0.0502368406091715 4.67384046377639 0.0933381955053341 0.0085947071401384 -4.98819244042644 11.2720975948381 -0.44252566112546 0.658407825600355 -66.8761049641896 21.7768039286742 -3.07097888116317 0.00231652420954153 LINC00339 other 1 1 1 -0.44252566112546 -3.07097888116317 0.00212820213199344 127.021662945061 36.3220611761622 3.4970940203257 0.000537074807791236 4.21213758497778 124.441287637486 0.0338483928039085 0.973019215380768 CEBPZOS other 1 1 1 3.4970940203257 0.0338483928039085 0.00141419629770332 36.3759168383155 13.0376846749644 2.7900595654201 0.00558586701502875 -56.2150507360965 35.4256681903879 -1.58684517773893 0.1135353137619 ZNF579 other 1 1 1 2.7900595654201 -1.58684517773893 2.84300356429518e-07 457.598969021746 87.0390885881293 5.25739614746098 2.67668189881755e-07 -291.712604047062 166.140033900187 -1.75582366994289 0.0800752146543081 RNASEK other 0.00305850323446875 1 0.00327625864415269 5.25739614746098 -1.75582366994289 0.443390038569595 24.2506131347079 20.4232665402623 1.18740129483696 0.235955556138908 -8.29467232437524 55.5688635925644 -0.149268345402787 0.881436511177003 FAM19A5 other 1 1 1 1.18740129483696 -0.149268345402787 0.742740024945309 27.24806296193 37.9985977169889 0.717080750317993 0.473847345518883 -23.8385623829711 160.726236949144 -0.148317803212888 0.882185382340982 RPL23P8 other 1 1 1 0.717080750317993 -0.148317803212888 1.17171441233525e-12 45.6347322113282 6.43433536865027 7.09237700503961 8.73030491580117e-12 -59.8108160594376 29.9334152100696 -1.99812870130894 0.0465620965098559 UMAD1 other 1.54115596654456e-08 1 1.20897262474015e-07 7.09237700503961 -1.99812870130894 0.0110691646916975 20.2888937415898 11.4105253730246 1.77808585304533 0.076348232712662 -38.1741247432658 25.5526742730631 -1.49393853399946 0.136186373246096 PPP1R3G other 1 1 1 1.77808585304533 -1.49393853399946 0.954616200022803 -1.51924754299103 5.19320940853259 -0.292545018595796 0.770060130651407 0.65480058488592 17.4569587885095 0.0375094306413166 0.970102282814675 FAM228B other 1 1 1 -0.292545018595796 0.0375094306413166 0.0123084784696084 11.7413005298022 4.52402168833179 2.59532366082263 0.00988692756165857 -5.36731549835669 9.6826712926962 -0.55432177093581 0.579747046737895 ZGLP1 other 1 1 1 2.59532366082263 -0.55432177093581 1.77288749622858e-07 117.497168933971 23.3231800890961 5.03778509127502 7.89933457865256e-07 -110.491322966456 44.423767614208 -2.48721188905007 0.0133855762262368 VAMP2 other 0.00192907888464632 1 0.0094578732910207 5.03778509127502 -2.48721188905007 0.502626020155833 -27.0797168359495 59.1644266685025 -0.457702683196388 0.647476675441062 214.444854827126 199.664722238387 1.07402475721821 0.28362078458441 RPL21P28 other 1 1 1 -0.457702683196388 1.07402475721821 0.000256059904028327 130.034017001227 63.7362054267401 2.04019075391444 0.0421520093576337 -322.569339803853 129.046371037772 -2.49963898410934 0.0129324122369147 MIR1282 other 1 1 1 2.04019075391444 -2.49963898410934 0.0184354608568166 1.82392907126436 10.4218070178067 0.175010827599091 0.861181806495602 -63.2160139520225 24.5747818639236 -2.57239369619086 0.0105504300863188 PPP3CB-AS1 other 1 1 1 0.175010827599091 -2.57239369619086 0.806845464658993 -0.331297438819903 4.2591127466598 -0.0777855526552383 0.938047253227123 3.60982680443029 7.81618544992885 0.461839963695225 0.644509900759934 EBF2 other 1 1 1 -0.0777855526552383 0.461839963695225 5.9241790932394e-10 21.8372308746167 3.28497291897198 6.64761366783218 1.29105897497104e-10 6.81926132485646 11.4156586687497 0.597360303310761 0.550690626129468 C6orf226 other 7.22512882211477e-06 1 1.75080507595822e-06 6.64761366783218 0.597360303310761 1.49005173936431e-06 214.236568677873 40.7320204725211 5.25965975153141 2.65130442896289e-07 -99.0203412945616 175.650930174148 -0.563733657410116 0.573331483907523 PPP3R1 other 0.0152223685693458 1 0.00324652227326505 5.25965975153141 -0.563733657410116 3.39046480828853e-33 204.809156896493 19.2389380629762 10.6455541478473 9.42421809920644e-23 -398.632295390233 60.2189991773223 -6.61970974005082 1.59115230939133e-10 FANCG other 5.1457084395395e-29 2.43223542013558e-06 1.41287877743303e-18 10.6455541478473 -6.61970974005082 4.79082389551114e-23 279.798769821208 27.1239805513162 10.3155497140935 1.03449466560548e-21 -193.446703338123 118.906837859971 -1.62687618996255 0.104753838042035 AP4M1 other 7.08514945907143e-19 1 1.54636262614707e-17 10.3155497140935 -1.62687618996255 3.28892269306354e-07 10.6379678762641 1.95394825198872 5.4443447340209 1.03710364914837e-07 -4.12495895300418 6.9297906510566 -0.595250154111833 0.552096977519095 C2orf16 other 0.00352671180377203 1 0.00129036436027041 5.4443447340209 -0.595250154111833 0.256369104296063 10.464284868717 7.77767295475265 1.34542618718915 0.179440225832478 -3.98788739730567 17.7862117485592 -0.22421229735043 0.822735201445602 PLXNA4 other 1 1 1 1.34542618718915 -0.22421229735043 0.0278152609859115 119.968311822012 95.6101019456596 1.25476606949124 0.210591680886313 -1010.29082168605 481.829623949996 -2.09678021331228 0.0368943166838801 CEBPD other 1 1 1 1.25476606949124 -2.09678021331228 0.398284351727373 1.36719492548728 1.88649675210866 0.724726890708438 0.469152492793035 -5.9649492474101 6.10804680762043 -0.976572288209743 0.329523254474567 ZNF816-ZNF321P other 1 1 1 0.724726890708438 -0.976572288209743 5.67142993857799e-08 4.82111037445397 2.24220115941946 2.15016853157913 0.032297971365857 -11.1917407612595 3.17846029132481 -3.52112020773261 0.000492759813112968 ARIH2OS other 0.000633725581336705 1 1 2.15016853157913 -3.52112020773261 0.284236366116325 -3.04530719538656 7.50409403372679 -0.405819434258096 0.685146494697928 -17.0430023651935 10.759912883217 -1.58393497699936 0.114196259885041 ZBED8 other 1 1 1 -0.405819434258096 -1.58393497699936 1.97288145841368e-15 12.0729550359091 10.545630958504 1.14483003277992 0.253135108511133 -104.932101314122 17.1153155589269 -6.13088908310501 2.57127039645307e-09 HMSD other 2.7312570910279e-11 3.91861608419448e-05 1 1.14483003277992 -6.13088908310501 0.278379093203169 54.6519355147472 37.1350065942892 1.47170932570002 0.142088303396957 -30.1357300922592 101.13021860737 -0.297989369619171 0.765905873705973 NPTXR other 1 1 1 1.47170932570002 -0.297989369619171 1.13138889273694e-12 44.6842529186554 5.94538701102933 7.51578540400504 5.79776555772999e-13 -8.21459195123417 25.9936464189107 -0.316023070362993 0.752192317355931 FAM200A other 1.48845522728471e-08 1 8.15687636317032e-09 7.51578540400504 -0.316023070362993 1.47630927434435e-38 292.150230844834 54.2818536277439 5.38209753941626 1.42615571553178e-07 -778.621364916541 99.6162956364746 -7.81620476792201 7.92093256761244e-14 PPP2R2A other 2.25299558357691e-34 1.21507105587175e-09 0.00176472508239902 5.38209753941626 -7.81620476792201 0.133145559382025 4.20191406249999 2.11118931932498 1.99030661250384 0.0474076491935721 0.686339285714288 4.83701061630183 0.141893276686466 0.88725359531618 C19orf73 other 1 1 1 1.99030661250384 0.141893276686466 0.669268520482623 5.97372914116357 7.32680272302535 0.815325506498273 0.415498164509794 -3.4422749037103 18.7452737008643 -0.183634283427485 0.854417769248198 ZNF880 other 1 1 1 0.815325506498273 -0.183634283427485 1.9896597654763e-12 1055.5263959713 143.137332838938 7.37422149090213 1.43594669003976e-12 -440.656736917931 299.288086283701 -1.47234974298384 0.141912361725308 TRIM16 other 2.60267393921955e-08 1 2.01190490741471e-08 7.37422149090213 -1.47234974298384 0.0102644836247639 6.44844744649597 2.85936676055032 2.25520123387561 0.0248024986763243 -23.1403239047152 13.3012604592245 -1.73970910318257 0.0828806863492342 XKR9 other 1 1 1 2.25520123387561 -1.73970910318257 0.000674884815911359 103.80562646778 27.0320599071984 3.84009309035813 0.000148257472785098 30.4304862641277 107.698034477619 0.282553775579365 0.777701590611719 SLC12A8 other 1 1 1 3.84009309035813 0.282553775579365 0.0518614001285868 -125.232546995733 149.599096093566 -0.837121013869006 0.403149286410741 -950.821329629091 392.605019195199 -2.42182672951604 0.0159981240270712 APOL6 other 1 1 1 -0.837121013869006 -2.42182672951604 0.000344251154187291 235.089177932874 59.8170751897876 3.93013495205146 0.000104335660646655 51.7477634792293 210.939516977414 0.245320384822774 0.806367611392372 FADS3 other 1 1 1 3.93013495205146 0.245320384822774 0.583146931602043 0.425282852618472 1.61544564183105 0.263260391811407 0.792519315271362 -6.38286045491509 6.61269527119902 -0.965243398212383 0.335151799810031 C3orf36 other 1 1 1 0.263260391811407 -0.965243398212383 1.12763161070525e-06 482.66983017907 103.371029935324 4.66929497056439 4.47999684494134e-06 -278.381050532696 234.483186739942 -1.18721113612909 0.236038859737418 CCNL2 other 0.0116315200644246 1 0.0514258837830817 4.66929497056439 -1.18721113612909 0.00119839127508227 674.194361068186 585.333073739518 1.15181320057819 0.25026034136098 -4147.35548574502 1365.41367175197 -3.03743515357038 0.00258292374571993 UBA52 essential 1 1 1 1.15181320057819 -3.03743515357038 6.57354758471251e-11 87.4925611376722 15.4378672397576 5.66739950401631 3.23633363946847e-08 -65.7189805550889 35.5664215009201 -1.84778163733421 0.0655566371521365 PPT2 other 8.27675376391152e-07 1 0.00041056128550297 5.66739950401631 -1.84778163733421 3.47600975893982e-14 35.3477324571857 4.3024426009885 8.21573597497023 5.43021391077036e-15 -0.0535987879200659 25.0612596262329 -0.00213871085170681 0.998294902178935 EXOC3-AS1 other 4.70860281945988e-10 1 7.82113709568255e-11 8.21573597497023 -0.00213871085170681 9.08163914875923e-05 108.659204781183 29.1508806983571 3.7274758833378 0.000229231298596569 -166.019847012179 92.2126223550301 -1.80040262137847 0.0727536324471516 TIAF1 other 0.785925051933624 1 1 3.7274758833378 -1.80040262137847 0.00963414906423761 19.3073480224204 6.33904167106843 3.0457834203141 0.00251365222517427 2.92049603700375 16.088490404423 0.181527039740214 0.856068837985547 BTBD19 other 1 1 1 3.0457834203141 0.181527039740214 7.38390842125346e-15 19.5689689585965 2.39671744849887 8.16490444914691 7.76319256450325e-15 -3.74938032422172 9.54337034101751 -0.392878007479899 0.694674482388554 FAM185A other 1.0132199135644e-10 1 1.11681288232944e-10 8.16490444914691 -0.392878007479899 0.127092441801498 15.3006399502718 9.38150331707896 1.63093690138308 0.103890489818806 -24.5334710093915 26.153943434708 -0.938040990668884 0.348933009313169 RAB6C other 1 1 1 1.63093690138308 -0.938040990668884 0.0173754823203814 1.79690787473001 6.37824655207919 0.281724430069931 0.778338064787369 -39.5972559494581 16.2845921901274 -2.43157799023448 0.0155851299731351 URAHP other 1 1 1 0.281724430069931 -2.43157799023448 0.38473697188789 23.0505501728419 16.9181833806435 1.36247194241993 0.174007130637922 -2.66951896392238 46.1751941811951 -0.0578128367678753 0.953933796383068 POTEJ other 1 1 1 1.36247194241993 -0.0578128367678753 0.226807648335803 29.5451868896416 33.2632749854646 0.888222428565807 0.375094570823008 -192.091995361732 137.133888338559 -1.40076240591597 0.162263244512032 CYTOR other 1 1 1 0.888222428565807 -1.40076240591597 0.0386037936546009 73.7770789462934 75.9536702218944 0.97134317184091 0.332111045463522 -323.16678179745 177.730317053794 -1.81829857254818 0.0699533024514251 C10orf55 other 1 1 1 0.97134317184091 -1.81829857254818 2.74730167719824e-20 10.4614048008268 1.03290151481371 10.1281725806294 4.43271076382774e-21 4.02692297476442 6.48317194211539 0.62113468695857 0.534955973505202 EHHADH-AS1 other 3.99457663864624e-16 1 6.61138810424908e-17 10.1281725806294 0.62113468695857 2.77164807258004e-12 15.7236313905313 3.19489713180221 4.92148283399089 1.37940421212265e-06 -16.9610313342183 4.78145326074914 -3.54725444530663 0.000447670631862889 TH2LCRR other 3.61256609780082e-08 1 0.0163335252757444 4.92148283399089 -3.54725444530663 1.18022161918967e-07 56.8873178828303 11.3298757024916 5.02100105743613 8.57960785863702e-07 -14.2518903301164 23.1274785520356 -0.616231912097567 0.538182326234702 NUTM2A-AS1 other 0.00129706355948945 1 0.0102620689597157 5.02100105743613 -0.616231912097567 5.03450874249037e-08 105.165133049369 17.7281098503354 5.93211199260363 7.78113283888937e-09 37.8986900963488 40.977554699182 0.924864608797785 0.355735430907195 LINC01615 other 0.000563965669333771 1 0.000100882387256201 5.93211199260363 0.924864608797785 5.02546928921451e-14 130.787334284032 20.9561279887145 6.24100665707259 1.37837129365187e-09 -139.500686078614 57.1627461318764 -2.44041260293516 0.0152126475177666 EXOSC6 essential 6.7868962750842e-10 1 1.82758249825301e-05 6.24100665707259 -2.44041260293516 4.69317203985862e-21 286.810654980524 32.7468052332066 8.75843163746812 1.18431522477152e-16 -146.981591091473 75.4694870339438 -1.94756313933027 0.0523443149651339 VPS52 other 6.86094820506932e-17 1 1.72637630314945e-12 8.75843163746812 -1.94756313933027 0.406633518357117 -2.92582618007863 40.5179489949889 -0.0722106190626896 0.942479405880692 113.150556131979 93.5638585301912 1.20934042171281 0.227424799702398 HLA-DQB1-AS1 other 1 1 1 -0.0722106190626896 1.20934042171281 0.0375145022568801 16.1736119698282 11.4427957008137 1.41343185640185 0.158528900791213 -39.7168229712403 24.4363672696718 -1.62531617457449 0.105108116946735 ZNF844 other 1 1 1 1.41343185640185 -1.62531617457449 5.47684317875361e-08 259.236433182509 101.395110749446 2.55669559672456 0.0110298345349479 -808.292866685431 205.151801997935 -3.93997449115054 0.000100150200417005 CKMT1A other 0.000612530141111804 1 1 2.55669559672456 -3.93997449115054 5.63727373364811e-06 291.442455605413 74.4670905234162 3.91370810322943 0.000111137697975806 -136.475948829869 136.614360152976 -0.998986846456322 0.318558229491585 TINCR other 0.0550028798192046 1 1 3.91370810322943 -0.998986846456322 0.00632537141219804 0.480664712653949 3.97019551571907 0.121068272519796 0.903712943649468 -26.8712699453404 8.70207912051352 -3.08791377016975 0.00219212993152415 RAET1E-AS1 other 1 1 1 0.121068272519796 -3.08791377016975 0.00567840731220111 54.2428961930043 19.7418924714474 2.74760366927616 0.0063468199601396 -62.2875092506975 68.3325232292669 -0.911535332036732 0.362706023195878 NSUN5P1 other 1 1 1 2.74760366927616 -0.911535332036732 0.789058570574978 -4.59383670745639 6.90265717760251 -0.665517146405924 0.506200688542899 -2.44903435138947 13.6632078802914 -0.179242998631537 0.857860694931895 TSSC2 other 1 1 1 -0.665517146405924 -0.179242998631537 0.1419388285877 2.67711021391696 1.35090134478116 1.9817214811868 0.0483658212085952 -0.176475868104404 4.33824991838389 -0.0406790460265013 0.967577134779856 LGALS8-AS1 other 1 1 1 1.9817214811868 -0.0406790460265013 0.639275798368057 -8.23966715699001 9.23974497724268 -0.891763482356295 0.37318976728091 -2.93703351183669 18.9075269066803 -0.15533673580541 0.876653792986033 LINP1 other 1 1 1 -0.891763482356295 -0.15533673580541 0.0142865233732625 3.50539751714214 4.5023062237193 0.778578209246366 0.43680354894951 -12.7679847270255 6.44928241083134 -1.97975277149938 0.0485878343871192 ENTPD3-AS1 other 1 1 1 0.778578209246366 -1.97975277149938 0.238415272945694 -458.100558266916 334.778778716917 -1.36836797129928 0.17215687782756 317.062804229932 768.040057622375 0.412820660958056 0.680014472212495 HLA-DPB1 other 1 1 1 -1.36836797129928 0.412820660958056 0.590373351405199 5.35446918144504 5.75961064851166 0.92965818493802 0.35325104088489 -4.89326955184929 25.7002145316636 -0.190398004103063 0.849118368686731 OSER1-AS1 other 1 1 1 0.92965818493802 -0.190398004103063 0.306265321059023 59.4792001997794 38.5956421982103 1.54108590535482 0.12428723857513 69.7489331334927 72.8102666628456 0.957954644727114 0.338811080814906 C1QTNF5 other 1 1 1 1.54108590535482 0.957954644727114 0.00190832119119566 11.8419877647258 11.6661956620977 1.01506850285387 0.310844853046524 -78.1156332155971 29.7854962514055 -2.62260640401151 0.00914614238914778 AFG3L1P other 1 1 1 1.01506850285387 -2.62260640401151 5.15630582866071e-20 308.481841887147 36.3416928303959 8.48837293647297 8.35342388835723e-16 -239.791270947411 82.4362101425031 -2.90880998208065 0.00388602409582615 CPTP other 7.48283101855242e-16 1 1.21066172413961e-11 8.48837293647297 -2.90880998208065 1.84233357033075e-09 30.447302004321 4.64642197157654 6.55284909346927 2.59682813018576e-10 -15.7697516758421 39.0357344652501 -0.403982450743446 0.686525436917162 EGFR-AS1 other 2.20343095011558e-05 1 3.49922590542531e-06 6.55284909346927 -0.403982450743446 0.430766397525543 4.76023487847414 3.90093012277271 1.22028201702076 0.223259290315685 6.71232434020465 8.30353669150583 0.808369323769121 0.419480435884039 SLC44A3-AS1 other 1 1 1 1.22028201702076 0.808369323769121 0.463856434974152 18.4980894144819 15.3145887152994 1.20787373127442 0.228016507494717 -6.77574470692612 55.7047934089219 -0.121636654447064 0.903265591076405 HAGLR other 1 1 1 1.20787373127442 -0.121636654447064 0.554418684354367 45.4737557187673 45.9507163639324 0.989620169544526 0.323107496475194 68.0842433441973 160.844083157062 0.423293428069182 0.672365533510525 LINC01133 other 1 1 1 0.989620169544526 0.423293428069182 6.05156774826009e-05 39.6176834295137 14.7458538180944 2.68669986277089 0.00759426545924332 -50.4606936756566 25.3599790190018 -1.98977663340523 0.0474690020214564 MSL3P1 other 0.534898073268709 1 1 2.68669986277089 -1.98977663340523 0.322719312772735 -24.7251663617539 18.2152783902575 -1.35738613662793 0.175615078565692 -46.2967136433391 73.3203281880262 -0.631430802172811 0.528209661112698 LINC01527 other 1 1 1 -1.35738613662793 -0.631430802172811 1.26771353077747e-06 18.6237413545517 3.68401799667131 5.05527968956156 7.26889349684072e-07 3.01208432232244 8.58493274898582 0.35085706672289 0.725927899685455 MDC1-AS1 other 0.0130320950963924 1 0.00871467641336234 5.05527968956156 0.35085706672289 0.0798318024495384 2.12610159283348 2.14162342865892 0.992752303874842 0.321647030242714 -7.39040034818645 4.38509892076453 -1.68534404393732 0.0929832553730008 SCEL-AS1 other 1 1 1 0.992752303874842 -1.68534404393732 0.689142302706114 -12.0360480111575 14.9089271050229 -0.807304772930475 0.420094333572746 7.19759132245606 34.2726006424164 0.210010071822451 0.8337942999483 PRR29 other 1 1 1 -0.807304772930475 0.210010071822451 0.45733522533941 109.689856755323 150.032264378137 0.731108453304843 0.465268735516985 430.940915324477 353.048710507161 1.22062735962248 0.223160796445095 C4B other 1 1 1 0.731108453304843 1.22062735962248 0.771778624993281 2.19080684289622 3.71180038835702 0.590227548272321 0.555454668857225 4.58409982977687 8.68774689464746 0.527651171859201 0.598107127868375 ADM5 other 1 1 1 0.590227548272321 0.527651171859201 8.49712017183904e-06 6.19862948121516 2.07004989727551 2.99443481501265 0.00296531048885308 -4.99324370856403 2.92011353004794 -1.70994848562688 0.0882508298202517 PRKAR2A-AS1 other 0.0816233363706858 1 1 2.99443481501265 -1.70994848562688 7.78265012138041e-10 265.680363813547 49.5621825230023 5.3605460915738 1.59139467175207e-07 -204.933321550156 136.251171893432 -1.50408483613222 0.133545823435787 ATXN1L other 9.45358510244078e-06 1 0.00196632725641686 5.3605460915738 -1.50408483613222 7.265323584292e-14 99.6969925205983 14.875106542794 6.70227081962615 9.30984116329322e-11 -47.05856245279 33.5038060477126 -1.40457362921019 0.16112103664472 SMIM13 other 9.79220312690876e-10 1 1.26567290614971e-06 6.70227081962615 -1.40457362921019 0.841132558223415 -8.05700291422354 14.5235550814763 -0.554754181674132 0.579450341943177 -0.931450312967827 33.3195315557649 -0.0279550842846909 0.977715400372605 HLA-DPB2 other 1 1 1 -0.554754181674132 -0.0279550842846909 0.093982819038257 -44.1123500505733 193.346422722335 -0.228151881113017 0.819675264164961 -885.113019112818 414.802701058323 -2.13381691308796 0.0336250474069172 HNRNPA1P10 other 1 1 1 -0.228151881113017 -2.13381691308796 9.80153349320745e-08 9.79034318203401 1.69214428162068 5.78576146748971 1.72823822186105e-08 6.08671702695941 3.83128337459199 1.5886888104714 0.113124376421784 ZMIZ1-AS1 other 0.0010823833436549 1 0.000221732963864773 5.78576146748971 1.5886888104714 3.55449671055199e-09 102.957953833417 25.2057335344923 4.08470373189204 5.59502006458961e-05 -118.787709926662 51.8691874092027 -2.29014017492756 0.0226696776974672 SVIL-AS1 other 4.20959045430672e-05 1 0.593799479454896 4.08470373189204 -2.29014017492756 0.00630081486844333 11.8583459808068 3.78112277567618 3.13619701986168 0.0018704520675226 -15.3289313174612 23.2084870369935 -0.660488178011234 0.509415770401506 LINC00885 other 1 1 1 3.13619701986168 -0.660488178011234 5.63669427150853e-06 161.108860108072 73.4426790768512 2.19366807057087 0.0289804707325446 -348.193412814134 118.207132217506 -2.94562101526534 0.00346015850334856 SH3BP5-AS1 other 0.0550028627013803 1 1 2.19366807057087 -2.94562101526534 0.0414449707251707 3.23016145654415 1.28168736263737 2.52024132460613 0.0122151103787422 -1.37972433906573 3.94954166243621 -0.349337836384455 0.727066187238774 RASAL2-AS1 other 1 1 1 2.52024132460613 -0.349337836384455 0.0470787227861201 13.647643853983 6.91002089590289 1.97505102510979 0.0491215354102324 -19.3525033704202 21.6250057861299 -0.894913211206295 0.371506110094483 NPIPA3 other 1 1 1 1.97505102510979 -0.894913211206295 0.216764808147871 21.9744315595931 24.9730721139809 0.879925043234508 0.379560239550217 -138.41728714205 107.640749852216 -1.28591901609834 0.19940103289511 PCOLCE-AS1 other 1 1 1 0.879925043234508 -1.28591901609834 0.151655686677493 4.54555773876426 2.61067239979465 1.74114444199195 0.0826193286946556 -0.930790863351565 5.92418224805881 -0.157117189238491 0.875251576431077 LINC00240 other 1 1 1 1.74114444199195 -0.157117189238491 1.74717715858635e-17 5.40044011468683 0.595062282591427 9.07541995632549 1.19917123794735e-17 7.94935789837205 3.58828083640086 2.21536670645475 0.0274408067302856 OPA1-AS1 other 2.47837079945473e-13 1 1.75762528345943e-13 9.07541995632549 2.21536670645475 0.065274293550392 78.8504552799653 33.6177701869896 2.34549926545935 0.0196177689558174 46.3477195695268 77.1420938048464 0.600809717283239 0.54839605845888 NDUFAF8 other 1 1 1 2.34549926545935 0.600809717283239 0.207265745714637 10.0216190787464 5.67947107970065 1.76453386910717 0.0785990852266718 7.91503167800606 13.065825284783 0.605781227399715 0.545090805283665 PRRT4 other 1 1 1 1.76453386910717 0.605781227399715 0.00822961310538203 4.14697475808394 1.45547790773216 2.84921862163165 0.00466938818352687 -2.60282508006474 5.6564996220415 -0.460147662685664 0.645725693657354 LINC01752 other 1 1 1 2.84921862163165 -0.460147662685664 0.0172136202380599 1.87408941519278 3.15305725845593 0.594372147910353 0.552685855648772 24.9551568747034 8.72057674642434 2.86164064606572 0.00449384036070634 TMEM233 other 1 1 1 0.594372147910353 2.86164064606572 0.00251169943522308 3.46855887107864 1.01243882411211 3.42594415432508 0.000692591231057898 -2.67050904642818 3.31536918077598 -0.805493717536197 0.421132950517363 TAF1A-AS1 other 1 1 1 3.42594415432508 -0.805493717536197 0.0817070184156509 2.4021603597136 2.45605638477505 0.978055868181384 0.328787826743114 -9.76209728568458 5.14225465729834 -1.89840798176523 0.0585446925229032 PPP1R26-AS1 other 1 1 1 0.978055868181384 -1.89840798176523 0.125349589335407 10.1822136053671 5.43229860232131 1.87438400404132 0.0617999372563427 17.4907516901314 10.788692452215 1.62121144592831 0.105969643557083 SFTA1P other 1 1 1 1.87438400404132 1.62121144592831 3.96305618327622e-05 14.833732519266 3.2647283083746 4.54363460543253 7.84642246091542e-06 10.937058371133 13.5094142483208 0.809587904412104 0.418778639571279 BOLA3-AS1 other 0.357745081664344 1 0.0887430380329534 4.54363460543253 0.809587904412104 0.0442454673486831 7.8831559413861 4.01073195131671 1.96551553109853 0.0502245518495399 -13.5736123257186 11.1304852440431 -1.21949870361519 0.223558694303358 RAB6C-AS1 other 1 1 1 1.96551553109853 -1.21949870361519 2.14471096126583e-13 65.6465540615449 9.26660120359557 7.08421055565368 8.99116253327893e-12 -16.8002496288407 21.6518465255243 -0.775926875753334 0.438367038019037 NUTM2B-AS1 other 2.86511937315502e-09 1 1.24482645273247e-07 7.08421055565368 -0.775926875753334 0.495662426250438 33.238335859862 35.8781860219991 0.926421860890112 0.354924947849524 -31.0163943630344 77.1700099970718 -0.401922901969448 0.688009076341927 GBP1P1 other 1 1 1 0.926421860890112 -0.401922901969448 2.05129626514885e-11 10.2141229951112 3.55977314724819 2.86931851345836 0.0043880210775964 -26.19172656317 5.72951014819018 -4.57137275015446 6.93919815441218e-06 MKRN2OS other 2.61930020096856e-07 0.102575227118521 1 2.86931851345836 -4.57137275015446 0.000762499526837185 5.71960300429182 1.59176286818305 3.59325067735785 0.000378137378922274 7.48820302295205 6.08344385622738 1.2309151197782 0.219261397931214 C2CD4D other 1 1 1 3.59325067735785 1.2309151197782 5.47076630898918e-05 3.92933011621544 0.993114920487333 3.95657142507463 9.37474379446115e-05 -1.66249014411818 2.07933188961918 -0.799530922609307 0.42457756170579 MTOR-AS1 other 0.485968171227509 1 0.974598364872181 3.95657142507463 -0.799530922609307 0.00270076549150769 186.853091654931 54.3916145199626 3.43532901723947 0.000669870951538419 155.403710324894 138.390455646909 1.1229366187029 0.262306201707634 ZNF469 other 1 1 1 3.43532901723947 1.1229366187029 1.06149540188029e-08 56.5738387617191 9.33344078901914 6.06141293876087 3.85279470517545e-09 4.70441398280321 32.1022190034973 0.146544822409027 0.883585049514236 SBDSP1 other 0.000122974242307832 1 5.04523466642725e-05 6.06141293876087 0.146544822409027 0.00570186476363438 275.67078257233 85.1075594999462 3.23908691768449 0.00132546627289669 118.372694891068 190.595538000076 0.621067503117626 0.534998724704776 MCRIP1 other 1 1 1 3.23908691768449 0.621067503117626 1.75095329784411e-06 33.9337392159809 6.70181165200738 5.06336808284023 6.96720854148629e-07 25.0380532163795 13.4120825180496 1.86682815160762 0.0628399135030594 FAM225B other 0.017768674066522 1 0.00835925680807524 5.06336808284023 1.86682815160762 7.79428608545913e-23 618.64799803912 105.956853649755 5.8386784500424 1.29863556337982e-08 -925.423526406274 170.614461860442 -5.42406262819179 1.1555507987429e-07 FGD5-AS1 other 1.15129399768317e-18 0.00174603725690052 0.000167199328785152 5.8386784500424 -5.42406262819179 0.00469563894172671 4.41716304638268 2.47745315732618 1.78294513190714 0.0755430629464817 -13.4013637924499 5.20736945403632 -2.57353811953217 0.0105163217095848 DBH-AS1 other 1 1 1 1.78294513190714 -2.57353811953217 0.0107830701869925 25.0083770851406 12.277211941546 2.03697526801769 0.0424803620435628 -22.9419301514383 25.1304464698331 -0.912913751014257 0.361979496552581 PROSER2-AS1 other 1 1 1 2.03697526801769 -0.912913751014257 0.856698663751332 -1.91682898324897 32.1592227432235 -0.0596043318134258 0.952508090194597 -51.6191496466138 93.360894232483 -0.552899049125152 0.580719773426779 MIAT other 1 1 1 -0.0596043318134258 -0.552899049125152 1.72255108051917e-05 15.444213078257 3.41516810345431 4.52224095869125 8.64792828873718e-06 -1.34640218911086 9.18342982578953 -0.146612128001435 0.883531080767975 TRAM2-AS1 other 0.160989623985322 1 0.0975832228101104 4.52224095869125 -0.146612128001435 0.0310068828316388 1.71027360719458 4.96585815426395 0.344406455856185 0.730768998196624 -27.7148739960465 11.1554552303018 -2.48442339858655 0.0134920671973384 FAM229A other 1 1 1 0.344406455856185 -2.48442339858655 3.02172887477829e-08 107.129995340939 27.6724124537932 3.87136450498569 0.000131212054943729 -161.504403564934 58.4348021037664 -2.76383931750364 0.00604346657081149 ERCC6 other 0.000342724488977354 1 1 3.87136450498569 -2.76383931750364 6.71752021928723e-09 6.4345975649631 1.03115405050103 6.24019035937119 1.41334470891911e-09 1.83658114757261 2.33913254135699 0.785154802090506 0.432954811451308 LINC00115 other 7.85949865656606e-05 1 1.87268173931782e-05 6.24019035937119 0.785154802090506 1.07211855017012e-22 254.229379096391 27.5465001343467 9.2290990817887 3.93784266745956e-18 -99.3285375066024 65.0877908021739 -1.52607019354058 0.127986329088543 NOL7 essential 1.58266140376113e-18 1 5.79020385823253e-14 9.2290990817887 -1.52607019354058 0.000264898017612015 26.5050001159042 14.3232714699772 1.85048507748114 0.0651768744037689 -76.2206583370039 33.3606450085712 -2.28474774146066 0.0229901255701141 CTAGE4 other 1 1 1 1.85048507748114 -2.28474774146066 0.364861848205953 8.69296874999998 7.38545721259417 1.17703867205082 0.240054814413118 -8.71250000000002 16.9210475898879 -0.514891288717058 0.606984450413991 NTF4 other 1 1 1 1.17703867205082 -0.514891288717058 6.05713194339989e-07 63.230193558665 11.5630493747358 5.46829746284896 9.22526585707347e-08 68.1940259671299 51.7409354735099 1.31798981489315 0.188458670939413 ELFN1 other 0.00636422853293027 1 0.00115048290503563 5.46829746284896 1.31798981489315 0.00106708400196461 8.44628865686069 6.54752807201622 1.28999655502963 0.197989150499478 -36.0149762439898 12.9173645445929 -2.78810558606287 0.00562087475279986 PIGBOS1 other 1 1 1 1.28999655502963 -2.78810558606287 0.0400409625227253 1.71783776984638 1.28899936437554 1.33269093633618 0.183581387280429 -4.18576507357501 2.55358796487067 -1.63917011325161 0.102160552990371 LINC01772 other 1 1 1 1.33269093633618 -1.63917011325161 0.44843094826766 -5.37348313505257 5.86854406464986 -0.915641609887644 0.360546538012377 -15.9772467870758 13.7603569058383 -1.16110700444818 0.246466495956274 ZNF503-AS1 other 1 1 1 -0.915641609887644 -1.16110700444818 0.00592509484738161 11.7150349283601 3.6946563131655 3.17080505881288 0.00166972907243583 2.74364191962631 8.55945084293474 0.320539479689985 0.748771941152076 FTCDNL1 other 1 1 1 3.17080505881288 0.320539479689985 4.8820400154292e-07 84.1570352436495 15.6823179449354 5.36636456033772 1.55105049540069e-07 -1.50100014888952 36.191332084081 -0.0414740232661882 0.96694402883656 BAIAP2-AS1 other 0.00516568654032563 1 0.00191725351736479 5.36636456033772 -0.0414740232661882 2.12493466668099e-08 3.37821529661219 3.47918165385245 0.970979854665402 0.332293954092713 -30.8507641974739 6.33910780773499 -4.86673600342144 1.7869329090359e-06 AP4B1-AS1 other 0.00024292253109497 0.0266878429964511 1 0.970979854665402 -4.86673600342144 2.17150138276862e-10 19.5515838052488 2.99189442800247 6.53485083639879 2.53945720926966e-10 -1.35862107447173 8.83577794775405 -0.153763605480497 0.877893970595386 TEX22 other 2.69244456449482e-06 1 3.42293437237457e-06 6.53485083639879 -0.153763605480497 0.0778398021155084 17.9529933220729 8.89650594652069 2.01798250121938 0.0444683689703365 -2.84502287497628 18.5353990692805 -0.153491320275454 0.878112337785385 ZNF32-AS1 other 1 1 1 2.01798250121938 -0.153491320275454 0.00112325597661439 13.2579392680241 3.68311223076002 3.5996566048948 0.000371926530179159 -3.8526493944597 14.9809023413206 -0.257170716868854 0.797220965212652 TMEM191A other 1 1 1 3.5996566048948 -0.257170716868854 0.20131789510289 6.93390077165426 16.3969270990098 0.422878063053229 0.672668259999211 43.5584332299965 24.4159770515992 1.78401352270043 0.0753689256689056 NPY6R other 1 1 1 0.422878063053229 1.78401352270043 1.58240843038967e-07 11.9741285480791 3.33773652276248 3.58749963228635 0.000386761166168327 -27.2115002448404 8.24026948573654 -3.30225853559061 0.00106900159684276 CFLAR-AS1 other 0.00172688232008425 1 1 3.58749963228635 -3.30225853559061 1.78282746768301e-07 1.47082069636323 0.552641126761319 2.66143908793538 0.0081784155207548 -5.06253070995529 1.42962321217387 -3.541164319973 0.000458317472332349 ST7-AS2 other 0.00193953800209235 1 1 2.66143908793538 -3.541164319973 4.22679493441305e-05 7.24994022656971 1.72700814422117 4.19797686005658 3.4967370268763e-05 -4.73234027211141 4.52460262161551 -1.04591290503689 0.296393113729908 LINC01876 other 0.380242472299798 1 0.37792733786479 4.19797686005658 -1.04591290503689 1.85189336506799e-06 10.0262200342465 6.53965982253216 1.53314091349239 0.126232264456198 -44.4322851805729 11.9242144516112 -3.72622325444417 0.000229847909478037 SLC16A1-AS1 other 0.0187485684279484 1 1 1.53314091349239 -3.72622325444417 8.63621194637146e-08 150.482693106288 28.7051059839361 5.24236674794028 2.91153858013898e-07 -164.201998574161 91.2148472396526 -1.80016744579691 0.0727908356945392 TMEM185B other 0.000956892283657958 1 0.00355790014492983 5.24236674794028 -1.80016744579691 0.724640101808251 7.70724037070244 11.8228854975523 0.651891653040037 0.514940470005972 -37.418252997997 73.4921641921047 -0.509146157407851 0.611001772288576 ADIPOQ-AS1 other 1 1 1 0.651891653040037 -0.509146157407851 1.868422933225e-05 12.8463432664742 2.85762498025292 4.49546156519712 9.74682225880869e-06 -6.07005691228631 13.0216482847917 -0.466151195265786 0.64142742959621 PLCG1-AS1 other 0.173987543541912 1 0.109515294899974 4.49546156519712 -0.466151195265786 0.660715136949497 4.36833846618802 5.27112373491424 0.828730017710178 0.407874893078744 -0.623104666105869 7.66935806981065 -0.0812460000477267 0.935297108443456 KIF4B other 1 1 1 0.828730017710178 -0.0812460000477267 0.228097253202189 7.48947034285306 4.42342673855998 1.69313764768968 0.0914147862619112 6.7602242568522 11.4874159748834 0.588489549924289 0.556624129301144 TEX41 other 1 1 1 1.69313764768968 0.588489549924289 0.399498595379302 -1.38547189196743 4.63854340963331 -0.298686844040326 0.765372863272734 -11.1436122182463 8.49540480981488 -1.31172233315732 0.190554119488191 ENTPD1-AS1 other 1 1 1 -0.298686844040326 -1.31172233315732 0.00171366233683236 3.33485927662835 1.2993922362365 2.56647622144279 0.0107312606898598 -5.78953164496911 3.30291345849968 -1.75285599144912 0.0805903540268418 LENG8-AS1 other 1 1 1 2.56647622144279 -1.75285599144912 8.75071497753379e-15 24.1111411099803 16.6439568050431 1.44864237467107 0.148448197253835 -135.947910903358 24.5917910795973 -5.52818257374297 6.8736147730943e-08 HSBP1L1 other 1.19963551627011e-10 0.0010400466513169 1 1.44864237467107 -5.52818257374297 9.30147670592499e-05 30.3939083403017 10.041001494644 3.02697976456973 0.0026719801944071 -109.779277797213 42.0744368994875 -2.60916808130948 0.00950522231113806 SRRM5 other 0.804391705528393 1 1 3.02697976456973 -2.60916808130948 1.18905992328746e-05 -19.9612004204328 4.87144006064349 -4.09759746028693 5.3072518353978e-05 18.806356473079 14.5904957968718 1.28894567634302 0.198356774169533 FAM30A other 0.112722880727651 1 0.564956957878096 -4.09759746028693 1.28894567634302 8.27361362047823e-19 39.0250733809171 7.11921304310046 5.48165550667683 8.61099841469988e-08 -58.665725876578 12.6533661878869 -4.63637304140766 5.18992358926597e-06 CACTIN-AS1 other 1.18842186044549e-14 0.0769302373636894 0.00107482482212284 5.48165550667683 -4.63637304140766 0.00948228229582516 72.2660193539954 23.7907996934053 3.03756159041712 0.00259391036053167 36.1017392441484 50.5711666326633 0.713879897341159 0.475854628397862 ERVMER34-1 other 1 1 1 3.03756159041712 0.713879897341159 0.0151941999141435 176.00826467896 60.5518123384502 2.90673817812709 0.00392342902299491 167.564325879431 128.712604500064 1.30184861482892 0.193963546171778 DANCR other 1 1 1 2.90673817812709 1.30184861482892 0.0228485536885904 -3.60195500677273 2.09965261133497 -1.71550045342148 0.0872214786849685 6.67792955399967 4.9061045289256 1.36114701890832 0.174424955434341 LTA other 1 1 1 -1.71550045342148 1.36114701890832 0.421301719343701 0.10179442324003 1.89777131883078 0.0536389301650663 0.957256414760743 -8.52780831673859 6.60114206035699 -1.29186862496903 0.197337796876441 SLC8A1-AS1 other 1 1 1 0.0536389301650663 -1.29186862496903 0.141977090703411 82.3888828076628 42.0836839104587 1.95773932203657 0.0511321282241512 -6.05551024681747 99.1114235169462 -0.0610980049719707 0.951319418667364 LINC00511 other 1 1 1 1.95773932203657 -0.0610980049719707 0.0716682382683841 -13.8846247222068 11.0540304183284 -1.25606898088366 0.210007222632634 -41.9854725754945 18.4799116574737 -2.27195201761231 0.0237527895936318 ITGB2-AS1 other 1 1 1 -1.25606898088366 -2.27195201761231 0.98450181562588 4.01367518389629 23.0786070940545 0.173913233478042 0.862044310494065 5.33294427289974 68.3622838471547 0.0780100367159061 0.937869131126073 C14orf132 other 1 1 1 0.173913233478042 0.0780100367159061 0.0392785300910099 1.21310339177455 6.90888143927895 0.175586077491172 0.860730544082742 -19.6982697034246 9.70373437314739 -2.02996794285039 0.0431893403170744 ZNF717 other 1 1 1 0.175586077491172 -2.02996794285039 3.63101682867044e-05 5.21465393631629 1.98383822579902 2.62856813045631 0.00899343517945642 -12.2046119424716 5.13197632145282 -2.3781504781021 0.0179939744467957 ST7-AS1 other 0.328752263667822 1 1 2.62856813045631 -2.3781504781021 0.0144961978286589 3.77443892625885 1.723371833766 2.19014773962665 0.0292440717484739 -3.15790592341796 3.54153428558134 -0.891677354720172 0.373244347108515 KLLN other 1 1 1 2.19014773962665 -0.891677354720172 9.24894181547889e-08 58.6500353204948 18.3312733553736 3.19945233391559 0.0015152761731035 -127.541865877671 38.8433950700435 -3.28348914011467 0.0011391300789244 PARG other 0.00102348790130089 1 1 3.19945233391559 -3.28348914011467 0.513378878223989 1.55845001203527 1.65331941273209 0.942618830961376 0.346657796912242 -1.22740108962383 3.31860002251196 -0.369855083859962 0.71175949118976 RBM26-AS1 other 1 1 1 0.942618830961376 -0.369855083859962 0.048587697647299 11.825686269678 29.7280461083349 0.397795611140497 0.691046089476395 -146.10995903971 65.8533715856006 -2.21871645326142 0.0272073443271116 TP73-AS1 other 1 1 1 0.397795611140497 -2.21871645326142 0.000124155275542511 3.72780289576736 0.885952943953032 4.20767595075003 3.36298818444062e-05 5.19983523693155 5.61088172230692 0.926741195819332 0.354765944057268 DLG1-AS1 other 1 1 0.363908951438319 4.20767595075003 0.926741195819332 0.00178662606573423 23.5437604741054 7.43015934063467 3.16867504379716 0.00167969389451357 -21.6192041031463 20.2724180328686 -1.06643440699053 0.287033758095844 LINC01806 other 1 1 1 3.16867504379716 -1.06643440699053 0.0146263272433259 4.39679682409596 1.50221638361054 2.92687316691911 0.00369299774002158 1.69766073691601 2.92769417774216 0.579862729455316 0.56245433192769 FGF7P6 other 1 1 1 2.92687316691911 0.579862729455316 0.00175067900970591 195.85425026313 65.1462272367438 3.00637901180967 0.00285506651727197 -42.3282531558719 143.298631867605 -0.295384907756687 0.76789323998805 AKR1B15 other 1 1 1 3.00637901180967 -0.295384907756687 3.66664388833757e-17 221.127874521763 53.5775824479867 4.12724621788292 4.69452856027493e-05 -449.453868473564 88.7844686526766 -5.06230284749262 7.02537191260503e-07 SCAMP4 other 5.17620117716614e-13 0.0105408680176726 0.502361501235021 4.12724621788292 -5.06230284749262 0.0499218266216093 -43.4942323647064 24.0341834899897 -1.80968212973916 0.0712832143243951 48.292516542476 56.1589168763956 0.859926067462567 0.390473568878517 LTB other 1 1 1 -1.80968212973916 0.859926067462567 0.000767566540907477 8.42501324664353 2.24143883512815 3.75875224191065 0.000203041653557696 9.82985729461307 7.01464416071022 1.40133370551726 0.162086433293122 SLC2A1-AS1 other 1 1 1 3.75875224191065 1.40133370551726 6.85019575524257e-11 58.9152292783249 9.59761336447398 6.13852913646245 2.46306605045441e-09 -23.6124910535334 22.6313205035593 -1.04335454264897 0.297571675959883 DNAJC9-AS1 other 8.61960131882173e-07 1 3.2445969082636e-05 6.13852913646245 -1.04335454264897 5.61663583347282e-08 280.871589542344 57.0946340976487 4.91940431848588 1.39112345273971e-06 -428.191747225427 171.834441798435 -2.49188546105154 0.0132125307196831 CERS6-AS1 other 0.000627715220748922 1 0.01646672831008 4.91940431848588 -2.49188546105154 0.0232627785269734 -13.7189938557147 11.1262554206714 -1.23302884366886 0.21849321109128 54.6101089349126 25.9137314153553 2.10738114320939 0.0358822513914952 SOX21-AS1 other 1 1 1 -1.23302884366886 2.10738114320939 0.0517950936581273 15.6145255985425 6.86125469859382 2.27575367545277 0.0235298057634396 -0.924858994528468 15.6905169443465 -0.0589438192386455 0.953034113196165 MRLN other 1 1 1 2.27575367545277 -0.0589438192386455 0.145987526536996 2.94951970453904 1.65835396455791 1.77858271971831 0.076266506297658 -2.2149016915312 6.44816454459565 -0.343493357871513 0.731455038841851 SNAP25-AS1 other 1 1 1 1.77858271971831 -0.343493357871513 0.00271157267497426 464.008735521644 133.798619980666 3.46796353795497 0.00059687698118516 366.303565493214 533.652420784281 0.686408514656181 0.49295729613302 POLR2J2 other 1 1 1 3.46796353795497 0.686408514656181 7.57171831257274e-05 18.9314986416064 4.28738300213209 4.41563038156188 1.38067196085901e-05 8.68199996698296 26.7441555706858 0.324631673041092 0.745672629712868 MELTF-AS1 other 0.661389594603229 1 0.153420268290653 4.41563038156188 0.324631673041092 0.739080677220387 3.86162172070874 5.64846775061368 0.683658275341872 0.494687257433359 -3.21735956905207 17.0020676062298 -0.18923342993138 0.850030209310511 RNF144A-AS1 other 1 1 1 0.683658275341872 -0.18923342993138 0.306242514399013 -19.6427187269306 12.7694539068791 -1.53825832100375 0.124976753864043 5.67490670213753 78.6260275289456 0.0721759305472778 0.94250713078843 NACAP1 other 1 1 1 -1.53825832100375 0.0721759305472778 0.201931625468478 1.71748256955886 1.39650313309116 1.22984512448405 0.219658518511817 -3.76098187606467 3.54394479228498 -1.06124166613774 0.289380373678696 EFCAB14-AS1 other 1 1 1 1.22984512448405 -1.06124166613774 1.17562846109695e-05 5.55807342393029 1.199891829277 4.63214540537319 5.32740869436712e-06 -6.67435738293223 7.54202138088074 -0.884956041075664 0.376864018092352 RALY-AS1 other 0.111484846965823 1 0.060918918420088 4.63214540537319 -0.884956041075664 3.36124993372829e-09 57.557743516429 8.94429793760883 6.43513263063513 4.50189986914929e-10 14.2981753739131 30.4208943222151 0.470011671007047 0.638666824793369 PCAT6 other 3.98442567144152e-05 1 6.04245000437218e-06 6.43513263063513 0.470011671007047 0.0018073036432028 101.493107207509 90.2683042571516 1.12434932773724 0.261712846494095 -350.450596930832 148.625569453534 -2.35794283728814 0.0189816846134844 C19orf24 other 1 1 1 1.12434932773724 -2.35794283728814 0.121258226574576 49.2962890773049 25.1741440165248 1.95821113301592 0.0513041202655244 5.54686028002463 45.9597874302978 0.120689424171879 0.904032827831528 CYP4F29P other 1 1 1 1.95821113301592 0.120689424171879 0.94439648645108 1.35155181357093 11.6951345101474 0.115565307299223 0.908069999961784 -10.2137104310107 35.475450319127 -0.287909253839799 0.773603750710953 GUSBP11 other 1 1 1 0.115565307299223 -0.287909253839799 0.00344895181968439 2.66401498853161 0.974726596569371 2.73308946109384 0.00662538983439956 -2.25982605985249 2.10762928699221 -1.07221230687939 0.284437705798309 TSTD3 other 1 1 1 2.73308946109384 -1.07221230687939 0.00208144318566944 275.40978377374 84.3803986201617 3.26390711915805 0.00121770402690862 -270.72872107813 293.570403769003 -0.9221935099805 0.357122409935761 OST4 other 1 1 1 3.26390711915805 -0.9221935099805 6.24201522844774e-05 -0.0421785142798372 1.58643214705476 -0.0265870269700109 0.978805797070234 -14.7007531366381 3.31542103275872 -4.43405316892911 1.27526754026921e-05 CCDC183-AS1 other 0.550233642387669 0.187234780262326 1 -0.0265870269700109 -4.43405316892911 2.10893181467832e-06 149.60328055139 30.461423367506 4.91123736230185 1.45222099391538e-06 -23.5662691741529 68.4080688626565 -0.344495460344995 0.730702137749226 FNDC10 other 0.0212559237601427 1 0.0171681565900676 4.91123736230185 -0.344495460344995 0.0201041546925611 15.1090581342948 5.39319404074727 2.80150464087536 0.00539615998847064 5.39665014270699 10.7931955217945 0.500004853225318 0.617415311158408 ZNF883 other 1 1 1 2.80150464087536 0.500004853225318 0.809337607480762 5.54726265085201 8.56122555565499 0.647951933375689 0.517480663255408 4.38698429311267 23.8427293549215 0.183996732412983 0.854132557995138 HOTAIR other 1 1 1 0.647951933375689 0.183996732412983 6.15203747156865e-12 32.2611760224652 4.45165012369625 7.24701517999766 3.21205312793047e-12 -9.54041293008036 18.9211791499925 -0.504218730474002 0.614454664349239 SNHG26 other 7.95827567322121e-08 1 4.4763172390839e-08 7.24701517999766 -0.504218730474002 0.243029940096214 33.7668269308424 21.1910714492667 1.59344594782209 0.112047409570126 0.415124236142856 31.1155203863491 0.0133413881879018 0.989363741918627 PROB1 other 1 1 1 1.59344594782209 0.0133413881879018 5.65780406177829e-05 4.85638048089399 1.63040814832169 2.97862868625445 0.00311817244142218 -5.68817238534129 2.72495270314172 -2.08743894115415 0.0376442200884769 TTC3-AS1 other 0.501734064198499 1 1 2.97862868625445 -2.08743894115415 0.819088568417149 -57.9842083481686 193.196933000931 -0.300130066494841 0.764274045384892 -321.829692383066 509.280669457143 -0.631929919362762 0.527886705141549 CES1P1 other 1 1 1 -0.300130066494841 -0.631929919362762 2.99773626604327e-08 86.9667253297638 72.9838192465707 1.19158912519983 0.234305393541852 -499.286954978538 101.016097730045 -4.94264742153106 1.24549942981939e-06 DHFR essential 0.000340123156745269 0.0186413899661068 1 1.19158912519983 -4.94264742153106 0.17152085594942 7.17033457956683 3.81636273678805 1.87883989916576 0.0611751802491541 5.29344520914708 8.91741538857433 0.593607562111489 0.553193973641327 SAPCD1 other 1 1 1 1.87883989916576 0.593607562111489 0.000726027087289298 -1.92378537106247 1.82842764270116 -1.052152858628 0.293525764821458 -14.9609886909673 3.99385544715191 -3.74600154886333 0.000213177035898215 WEE2-AS1 other 1 1 1 -1.052152858628 -3.74600154886333 0.178748110256543 15.3479066476885 9.63848184698529 1.59235727071365 0.112291742715383 -6.44781032767944 22.5971909239991 -0.285336807984908 0.775570710951434 HCG22 other 1 1 1 1.59235727071365 -0.285336807984908 5.21380841837379e-18 114.814812770383 12.8959421688059 8.90317367025032 4.44371862501806e-17 -20.6959901677027 29.2539392769242 -0.707459941438654 0.479805434784109 LINC01128 other 7.43332666207552e-14 1 6.49316165487639e-13 8.90317367025032 -0.707459941438654 0.0254273263935542 3.49839012124127 1.3391998037277 2.61229886048624 0.00942181535465659 -1.30701133429867 6.19039945234194 -0.211135217421907 0.832917424138968 LAMA5-AS1 other 1 1 1 2.61229886048624 -0.211135217421907 1.82445826624859e-19 17.5939327303634 1.77806495193309 9.89498876924352 2.80030131062878e-20 5.10923954292482 4.13267023852264 1.23630467664686 0.217266377645898 UBAC2-AS1 other 2.63561241142271e-15 1 4.16488813929819e-16 9.89498876924352 1.23630467664686 8.04170275192553e-19 44.1641507453282 6.92762179807958 6.37508109313517 6.45111621772728e-10 -54.0625036241666 12.9791487802757 -4.16533507238354 4.01273568142812e-05 MED4-AS1 other 1.15551226842418e-14 0.580723107816277 8.62772282958846e-06 6.37508109313517 -4.16533507238354 0.192682602605723 344.414848413314 214.752728431163 1.60377402852748 0.109750368392317 -328.2507563677 613.567524373644 -0.534987174725051 0.593030276758545 RPL41 essential 1 1 1 1.60377402852748 -0.534987174725051 0.453395433759284 -55.9851927809214 299.015204198882 -0.187231926653751 0.851597448817363 579.674061122317 594.288958230213 0.975407759297062 0.330094811429338 VIM-AS1 other 1 1 1 -0.187231926653751 0.975407759297062 0.0381921502399964 4.78140848826418 1.87111266885723 2.55538245657029 0.0110751188604465 3.73921948851206 4.32266273046417 0.865026887746696 0.387680233849224 LINC00242 other 1 1 1 2.55538245657029 0.865026887746696 0.593840183232586 -100.291927413484 148.947642836211 -0.673336788040138 0.50121905891747 -333.293091595267 343.949200993769 -0.969018362689277 0.333267850848467 HLA-DRB6 other 1 1 1 -0.673336788040138 -0.969018362689277 0.079403837347065 -3.34131021242313 15.799734412963 -0.211478884713513 0.832648227597032 69.9425963956156 31.5585629493748 2.21627950891855 0.0273754099028138 RALGAPA1P1 other 1 1 1 -0.211478884713513 2.21627950891855 0.0159027317275702 -4.89050416641686 2.20681017774438 -2.21609643445434 0.0273947497013579 -11.4496672861339 4.46481567563251 -2.56442104623096 0.0107951558671791 PATL2 other 1 1 1 -2.21609643445434 -2.56442104623096 0.703992840682947 9.92826975505811 13.6980762369592 0.724792998908148 0.469108657125498 -1.94675133373315 27.2638122705001 -0.0714042230931722 0.943120653755296 NKX1-2 other 1 1 1 0.724792998908148 -0.0714042230931722 0.00938547018451181 6.85058872918457 2.9257991001328 2.34144194277509 0.0198226918157462 -1.86030426004042 4.19103093759023 -0.443877482114238 0.657431159658495 ACVR2B-AS1 other 1 1 1 2.34144194277509 -0.443877482114238 1.45246998699314e-06 46.5145448475406 8.79167713805546 5.29074761471833 2.2770190343132e-07 1.71536835076784 53.1691707238687 0.0322624620134949 0.974283048136303 MBNL1-AS1 other 0.0148602204369268 1 0.00279504086461945 5.29074761471833 0.0322624620134949 0.540977674502522 6.49346223825826 10.5870305158303 0.613341222408769 0.540087805913272 26.5326405484608 24.3628731639876 1.08906040637606 0.276949294739902 C2-AS1 other 1 1 1 0.613341222408769 1.08906040637606 1.16931485771903e-06 9.94030533193606 1.86203057968816 5.33842217220771 1.78032524114656e-07 -2.36246317778344 6.59178523339116 -0.358395046885965 0.72028401360798 UBE2Q1-AS1 other 0.0120509589236523 1 0.00219425085971314 5.33842217220771 -0.358395046885965 0.00185615411632815 42.249110885743 13.8919496008736 3.04126577619357 0.00255438939494685 -45.5254451098025 47.8193887599837 -0.952029005186683 0.341814519011518 ZNF688 other 1 1 1 3.04126577619357 -0.952029005186683 0.00460351955332205 39.5568010762751 37.8200592704547 1.04592118149262 0.296386825535139 -165.663177393685 70.2216713488254 -2.35914603300675 0.0189175375279049 PET100 other 1 1 1 1.04592118149262 -2.35914603300675 0.20639499184945 7.75740701828116 4.70100579148319 1.65015900051331 0.0998915622771062 0.860080438541202 9.0678846546203 0.0948490713435543 0.924494073880798 EMX2OS other 1 1 1 1.65015900051331 0.0948490713435543 0.0127703190546708 33.0235167319977 11.4213133179645 2.89139399407379 0.00410203728337017 -9.40818584867385 36.2929630065589 -0.259228926747414 0.795627939761179 STEAP3-AS1 other 1 1 1 2.89139399407379 -0.259228926747414 0.0949256142639736 -14.1274216059906 7.94123225549042 -1.7789961496496 0.0761925501363781 -33.6760633615263 20.6721742591229 -1.62905280012646 0.104288924776128 LINC01315 other 1 1 1 -1.7789961496496 -1.62905280012646 0.0705349135479185 -3.8958807494267 2.73174552602237 -1.42615068362513 0.154812003715512 -10.4747209121198 4.65101430436103 -2.25213689459052 0.0249998041483165 GK3P other 1 1 1 -1.42615068362513 -2.25213689459052 0.140908917203162 2.15906667343726 1.14402931504271 1.88724768242207 0.0600347329182359 -1.35097496572386 2.72778075453176 -0.495265231078207 0.620753885761048 TOB1-AS1 other 1 1 1 1.88724768242207 -0.495265231078207 0.00398325236260351 4.38236511789834 1.38908280194663 3.15486241119463 0.00175871644748948 -5.38542548787142 5.76098838058023 -0.934809295228784 0.350593668692261 ALMS1-IT1 other 1 1 1 3.15486241119463 -0.934809295228784 0.00480669449655537 -15.662233367221 4.82114273532995 -3.24865581191906 0.00128427778534663 -16.0490251794915 19.6464615005629 -0.816891386727918 0.414605924867661 ANKRD36BP2 other 1 1 1 -3.24865581191906 -0.816891386727918 3.64661333242678e-10 16.4274959211303 2.47728113807393 6.63126024279287 1.4172952959844e-10 6.1820868191759 4.32806431002261 1.4283722182362 0.154160037527148 PRRT3-AS1 other 4.48387575355197e-06 1 1.91986820794046e-06 6.63126024279287 1.4283722182362 0.359454251892514 2.58018527356609 1.81158836433191 1.42426686126218 0.155359113846559 -2.2464631260659 11.5251396264192 -0.194918517161937 0.845582395358104 TPRG1-AS2 other 1 1 1 1.42426686126218 -0.194918517161937 0.906771539725348 -0.388446235355748 3.77197963061083 -0.102982060720419 0.918041916648702 3.77816893665986 8.96722601389134 0.421330847556091 0.673797257330607 HOXB-AS1 other 1 1 1 -0.102982060720419 0.421330847556091 0.281811744457294 -13.0163362015214 8.26276140483889 -1.57530098762124 0.116178169526414 -18.9522800016628 21.08526956349 -0.898839824864248 0.369415934777308 FEZF1-AS1 other 1 1 1 -1.57530098762124 -0.898839824864248 0.00602751878857606 15.6047389517432 6.67768853622071 2.33684737871509 0.0200637191964033 -13.9566873827944 15.2600109591599 -0.914592225401838 0.361094372093965 TPI1P2 other 1 1 1 2.33684737871509 -0.914592225401838 0.0479327481471909 5.65161490106953 3.26647770083849 1.73018627974065 0.0845764327699472 -6.91302832510065 6.44303806151426 -1.07294544267769 0.284116869686916 GOLGA6L17P other 1 1 1 1.73018627974065 -1.07294544267769 0.120635838577055 0.208549532948883 3.5346491665028 0.0590014802389067 0.95298822287766 -12.4590591971653 6.97407629375377 -1.78648163174299 0.0749798913088921 LRRC37A6P other 1 1 1 0.0590014802389067 -1.78648163174299 9.30515740199428e-07 19.7275852065643 4.07644174459964 4.83941300834211 2.05389719033887e-06 -8.83783431963363 11.5322085469364 -0.766360951908166 0.444042856693379 ANKRD18B other 0.00965875338327006 1 0.0240614055848199 4.83941300834211 -0.766360951908166 0.0330925535104887 9.25901866553382 4.18280272036763 2.21359200625174 0.0275684924379195 -17.7993415288214 18.7166999499134 -0.950987170625867 0.34233538207469 PSMG3-AS1 other 1 1 1 2.21359200625174 -0.950987170625867 0.0015780666477086 13.2893218877114 3.92062427161851 3.38959333183574 0.000792982870438902 -10.21527260197 16.2851696014574 -0.627274560349426 0.530953228712854 THAP7-AS1 other 1 1 1 3.38959333183574 -0.627274560349426 0.527743913155488 1.45956212714638 1.94641805232151 0.7498708334551 0.453906761448703 -1.86717394320353 4.02527553427349 -0.463862393345585 0.643075061839679 ZNF32-AS2 other 1 1 1 0.7498708334551 -0.463862393345585 2.29358109220791e-05 37.0988661494878 8.86986575913962 4.18257357629801 3.77505402415037e-05 -38.3962251776026 33.5620816206275 -1.14403586796607 0.253508772632224 GTF2IRD1P1 other 0.211881021298166 1 0.407101825964376 4.18257357629801 -1.14403586796607 0.655989920787172 -12.2322752684148 15.6036064791389 -0.783938974926637 0.433655795041548 -44.5029866393342 71.0449620977279 -0.626405945267687 0.531495293236735 PRB4 other 1 1 1 -0.783938974926637 -0.626405945267687 0.0289710305492519 2.50603605729086 1.02162171297605 2.45299803778701 0.0147020062585166 -2.55437355692636 4.26359972151578 -0.599111953224877 0.549523459118877 KLHL7-AS1 other 1 1 1 2.45299803778701 -0.599111953224877 0.140212725059331 7.94222575473802 12.2335233483151 0.649218179309879 0.51666450920739 51.285328467755 25.7933635240617 1.9883148787444 0.0476311760132211 SETSIP other 1 1 1 0.649218179309879 1.9883148787444 0.19341432276356 1.89567358593474 1.72234214829293 1.1006370527561 0.271884482837041 -5.96829983316757 5.01704965665497 -1.18960350038609 0.235086922678078 FBXW4P1 other 1 1 1 1.1006370527561 -1.18960350038609 0.00875919538323984 -13.0345496433715 6.37841259009555 -2.04354131365093 0.0418174902703597 -41.5055394057916 14.9271865716887 -2.78053330454863 0.00574835714327677 FOXD3-AS1 other 1 1 1 -2.04354131365093 -2.78053330454863 0.0116679528860667 484.129544554931 172.120416478318 2.81273746868905 0.00521760934422338 640.455589007901 582.917744961126 1.09870662635362 0.27272719664151 MIR205 other 1 1 1 2.81273746868905 1.09870662635362 6.35438717692596e-10 219.977105551054 79.8603701042072 2.75452148874357 0.00621408263753391 -872.735841151091 206.648193950491 -4.22329285568391 3.14207346624453e-05 HSBP1 other 7.74091445893121e-06 0.456354750237355 1 2.75452148874357 -4.22329285568391 1.39953926250061e-09 33.2169212947034 5.33933907027549 6.22116723765017 1.55346787462662e-09 -45.9820384006608 18.7171432790162 -2.45668036597291 0.0145567020870653 MIR92B other 1.68154642389448e-05 1 2.05632542564326e-05 6.22116723765017 -2.45668036597291 0.0163417972281902 27.8069128477551 10.591201568099 2.62547291437738 0.00907247295520406 -1.71906359604847 21.0585193154572 -0.0816326908030355 0.934990321428455 LINC01468 other 1 1 1 2.62547291437738 -0.0816326908030355 0.605920631858053 2.67481440331299 2.71105962761175 0.986630606007477 0.324569165426637 3.65949664069778 5.57406747805955 0.656521768906129 0.511960294122334 KLF3-AS1 other 1 1 1 0.986630606007477 0.656521768906129 0.00500818858805265 12.920570283403 5.36328572139969 2.40907737431358 0.0165574497213409 -40.7567053139211 25.0893326653817 -1.62446350636329 0.105261450832239 APCDD1L-AS1 other 1 1 1 2.40907737431358 -1.62446350636329 0.0299558306639123 12.4481640731641 4.87796769537711 2.55191605408977 0.0111791529299484 18.9660607577274 9.9969581526887 1.89718316992519 0.0587066979921599 LINC00704 other 1 1 1 2.55191605408977 1.89718316992519 0.524675474212776 -394.591464485096 452.307850652985 -0.872395789538992 0.38364660477304 358.578074378133 1037.67194865215 0.345560150145617 0.729900351159885 HLA-DPA1 other 1 1 1 -0.872395789538992 0.345560150145617 0.189246272341869 -16.2110223832264 9.07974905364808 -1.7854042317076 0.0751701571798417 5.94327776511101 33.9986390532254 0.174809284448319 0.861343240275745 LINC01305 other 1 1 1 -1.7854042317076 0.174809284448319 1.66320124505743e-05 3638.23066722994 974.424183390123 3.73372369984923 0.000223386166023464 -3027.3813301342 2245.69367149594 -1.34808294139136 0.178588172142606 RPS18 essential 0.155708900562276 1 1 3.73372369984923 -1.34808294139136 3.41993319525623e-07 39.9050505586043 7.31900555171675 5.45225034694012 9.95781175535391e-08 24.960408523732 14.6472493568639 1.70410210924928 0.089332738861614 FAM225A other 0.0036651424053561 1 0.00124024545412933 5.45225034694012 1.70410210924928 0.00268047434788764 45.8493697791252 14.9035928436742 3.07639709834035 0.00228514151088873 -56.6787062635629 49.5192740945573 -1.14457869788912 0.253281133653675 FAHD2CP other 1 1 1 3.07639709834035 -1.14457869788912 0.135509813741572 4.15615710242112 3.24241743986904 1.28180815070776 0.200837885501492 -5.65922253798459 7.34914207487119 -0.770052134021887 0.441837060668933 LINC-PINT other 1 1 1 1.28180815070776 -0.770052134021887 0.635842104533272 -1.71053758875245 3.9333194779388 -0.434883969722396 0.663939783136344 -8.32608841297092 8.90085502647359 -0.935425685308528 0.350274329095919 PIK3CD-AS2 other 1 1 1 -0.434883969722396 -0.935425685308528 0.555259528907205 -5.3713219579176 5.00798394175064 -1.07255175343872 0.284280461434469 0.166177434953506 9.5535651910079 0.0173942849220223 0.986132908505763 PCAT7 other 1 1 1 -1.07255175343872 0.0173942849220223 0.00492903670714374 4.29303677947308 11.2869752258098 0.380353167574624 0.703936407339339 131.657096609814 40.0756261413232 3.28521620961171 0.00113239938285758 LINC01819 other 1 1 1 0.380353167574624 3.28521620961171 0.873640477491918 -1.1230980748266 2.8228041681399 -0.397866096239568 0.690999248725384 1.03778968697964 6.59636889166637 0.157327418163461 0.87508792928476 CYP21A2 other 1 1 1 -0.397866096239568 0.157327418163461 1.65655600415484e-05 41.1583821505814 9.49938998451728 4.33273949355317 1.97568821975543e-05 -61.1031647275881 32.3087280703396 -1.89122780056708 0.059499752356678 IPO9-AS1 other 0.155103338669018 1 0.217226919762109 4.33273949355317 -1.89122780056708 0.793128142969359 64.9911319653356 163.85653240497 0.396634366731933 0.691901479835364 -405.572766995197 858.529024096568 -0.472404258460547 0.636960271322298 PRH1 other 1 1 1 0.396634366731933 -0.472404258460547 0.664473579861644 -0.281834631565674 1.69531726034985 -0.166243002508872 0.868071035775395 -3.50692480582864 3.88250079107972 -0.903264415009524 0.367067146041792 TRAF3IP2-AS1 other 1 1 1 -0.166243002508872 -0.903264415009524 1.42501702110545e-06 22.2462377384199 4.85558204249463 4.58158003381002 6.66560289981654e-06 -23.1663932847331 12.518833057087 -1.85052338177945 0.0651772890461156 DARS-AS1 other 0.0145893242620776 1 0.0757679081622146 4.58158003381002 -1.85052338177945 0.115199072388019 674.090509119353 383.869130119314 1.75604250570978 0.0800407758252946 -337.431893183376 884.67886048602 -0.381417380085243 0.703147485191623 TAPBP other 1 1 1 1.75604250570978 -0.381417380085243 0.468161640241209 -11.0451841876869 10.791966285569 -1.02346355570592 0.306861794944844 4.85166856780689 15.7020510015972 0.308983111016095 0.757535445855924 PPP1R2P3 other 1 1 1 -1.02346355570592 0.308983111016095 0.024614786795254 0.62126255912014 2.99933929446393 0.20713313771031 0.836038455653807 14.256832743469 5.4443221400414 2.61866075826303 0.00925028956373491 LEF1-AS1 other 1 1 1 0.20713313771031 2.61866075826303 0.000217973972526712 16.920113038727 4.81294448340948 3.51554294819972 0.000502200551254337 -7.27906299867745 10.8908711976287 -0.668363702645051 0.504383266481827 ZBED9 other 1 1 1 3.51554294819972 -0.668363702645051 0.0259043667558819 1.79363390540143 1.31291226396589 1.36614909817616 0.172860517992056 -7.35346714938145 3.66234015168358 -2.00786023275338 0.0455063316299175 TMEM253 other 1 1 1 1.36614909817616 -2.00786023275338 5.65899753524124e-10 65.5696085336032 55.9671447071297 1.17157323062883 0.242240013362812 -397.779435155218 80.0540901212327 -4.96888334565826 1.09881192220782e-06 TMA7 other 6.90963599052956e-06 0.0164525109112176 1 1.17157323062883 -4.96888334565826 0.00885629052489325 20.219308853145 16.3714867164512 1.23503193102354 0.217727486936209 98.174775324816 31.7482720265945 3.09228720361783 0.0021615809521692 LINC00865 other 1 1 1 1.23503193102354 3.09228720361783 8.64431524123509e-05 6.91327586773424 1.98677343333726 3.47964984418064 0.000571675224991915 -7.06176587019076 4.42963685422397 -1.59420875854798 0.111876462162145 GNG12-AS1 other 0.749635017719907 1 1 3.47964984418064 -1.59420875854798 1.82701634814853e-12 118.238130366922 16.5518007014119 7.14352066581106 6.23803344249427e-12 -72.2201749210434 69.0284884998754 -1.04623723466252 0.296246106117885 SMIM26 other 2.39156439972642e-08 1 8.65589520480505e-08 7.14352066581106 -1.04623723466252 0.000193272085612472 5.64507238307352 10.4938041521975 0.537943371269357 0.59099124737513 -88.762130357711 21.8944102248332 -4.05410008519137 6.32979960250769e-05 C9orf172 other 1 0.909718798872406 1 0.537943371269357 -4.05410008519137 0.00755266025646441 6.90300932466801 2.65236314166736 2.60258831689562 0.00968560225228584 -13.4734532144464 11.9830041733863 -1.12438024885031 0.261699754080484 MHENCR other 1 1 1 2.60258831689562 -1.12438024885031 0.0795484820094057 -201.514092728486 96.0017077094402 -2.09906779302709 0.0365941025401756 -4.34754988173916 220.244417533264 -0.0197396598307993 0.984263355199007 HLA-DQB2 other 1 1 1 -2.09906779302709 -0.0197396598307993 5.32224484499964e-05 15.4793362738478 5.94677201490378 2.60298128716782 0.00968031321343904 -22.5915735022102 11.784473950625 -1.91706253472705 0.0561372585292745 IDI2-AS1 other 0.473200789168918 1 1 2.60298128716782 -1.91706253472705 0.12353131302423 57.5649234631655 29.5358500087695 1.94898482508795 0.0521762850636842 -4.35305573759193 83.2777427641751 -0.052271538506019 0.958345151257035 LINC00665 other 1 1 1 1.94898482508795 -0.052271538506019 0.296332551528799 1.84175392158824 5.68855468401362 0.323764826725507 0.746327585000907 -36.7833600600661 25.9261701645789 -1.41877337942958 0.15693831821754 SLCO4A1-AS1 other 1 1 1 0.323764826725507 -1.41877337942958 0.241082942389601 8.60125687246981 13.2840609125818 0.647487009361971 0.517781032762138 -37.3021858275469 31.039892529795 -1.20174983826831 0.230349075624364 TNF other 1 1 1 0.647487009361971 -1.20174983826831 0.0667543460871431 27.4042400333634 12.0111722721398 2.28156248303325 0.0231778995439289 0.733495569107768 29.3788235220014 0.0249668121856024 0.980097144340985 COL4A2-AS1 other 1 1 1 2.28156248303325 0.0249668121856024 0.00279373379006082 8.36277950797619 2.43912522296949 3.4285978551749 0.000686613377775101 10.9205887123625 10.3052151377664 1.05971477221673 0.290078612913452 RPS2P32 other 1 1 1 3.4285978551749 1.05971477221673 3.78805657841134e-21 73.4422078257132 7.28629436185447 10.0795005222684 6.57198638040437e-21 -9.69472913055408 29.6386339128016 -0.327097704944042 0.743809872899463 PET117 essential 5.53965394026874e-17 1 9.79291690544055e-17 10.0795005222684 -0.327097704944042 0.463046144388123 8.24131567830927 7.76491194687671 1.06135339778376 0.289363554027313 -9.14402777204312 18.8609055854224 -0.48481382458701 0.628154150452299 LYRM9 other 1 1 1 1.06135339778376 -0.48481382458701 0.390550039756728 0.390781249999997 1.77424734385684 0.220251844452826 0.825815468686995 -5.17035714285716 4.06503251964387 -1.27191040117685 0.204328512004234 SEC1P other 1 1 1 0.220251844452826 -1.27191040117685 0.00379425809342602 1.94139341691597 2.42289588054692 0.801269849234187 0.423569992282425 -14.4635279247909 5.12558692766982 -2.82182862741267 0.00507362945092289 DPYD-AS1 other 1 1 1 0.801269849234187 -2.82182862741267 6.11906415199455e-25 100.264948811728 9.15450612637698 10.9525240824115 7.19640934782534e-24 -77.4949770951152 50.0249492714978 -1.54912655032453 0.122355374613642 DLGAP4-AS1 other 9.11862939930228e-21 1 1.08147639679119e-19 10.9525240824115 -1.54912655032453 0.235378514023976 -4.37579617834396 2.53719602457493 -1.72465829835795 0.0906455861271133 -2.84430290162775 4.41372546219024 -0.64442225190334 0.522189704113165 RPL23AP87 other 1 1 1 -1.72465829835795 -0.64442225190334 9.56362273871928e-18 79.3938151750291 10.4362873541929 7.60747691976223 3.14647242811569e-13 -54.517194876329 23.9426369006972 -2.2769920916581 0.0234464595634373 HCG25 other 1.36032969835543e-13 1 4.44376301022778e-09 7.60747691976223 -2.2769920916581 0.115859248009409 60.2632369647982 29.2945883160122 2.05714571970478 0.0404823284181106 7.9095506075241 117.479467680447 0.0673270892666851 0.946363358107184 SNHG15 other 1 1 1 2.05714571970478 0.0673270892666851 0.383156470611853 5.41370913658866 6.99760684888843 0.773651514510083 0.439709837473763 -24.0646555867239 23.9671705378957 -1.00406744086349 0.316107116901799 CYP1B1-AS1 other 1 1 1 0.773651514510083 -1.00406744086349 0.258362950673425 2.27329552310847 1.81112970099927 1.25518096349158 0.210331784913456 -1.41744901653193 2.71051982496777 -0.522943607892181 0.60137651972001 MIR3936HG other 1 1 1 1.25518096349158 -0.522943607892181 3.84098177236399e-06 146.263242750592 29.3406430841029 4.98500466848458 1.02166791055935e-06 -24.7184839552606 61.3989246831919 -0.402588222559333 0.687522522827298 SNHG7 other 0.0379988326739969 1 0.0121762381580464 4.98500466848458 -0.402588222559333 2.85920706567701e-06 4.6343351563902 0.899452205502062 5.15239734589719 4.50758070223326e-07 4.41989280113598 4.15230168749821 1.06444404423779 0.287930123140242 LINC01271 other 0.028557760171982 1 0.0054591309884747 5.15239734589719 1.06444404423779 0.481701836239346 -1.1892889954193 1.69745147050247 -0.700632104119745 0.484041748327186 3.62942477988567 4.4547593171467 0.814729712987128 0.415832956266523 LINC01399 other 1 1 1 -0.700632104119745 0.814729712987128 0.405868393997461 -5.44764177990322 4.07393906242518 -1.33719275041397 0.182112440476377 -2.35933700448848 9.68508208345526 -0.243605266755443 0.807693133146083 HOXB-AS3 other 1 1 1 -1.33719275041397 -0.243605266755443 0.0822172576525539 0.0811735772277342 0.948955325541259 0.0855399353825587 0.931885809590277 3.95137091835724 1.91670302019892 2.0615457255069 0.0400608851900492 CTAGE7P other 1 1 1 0.0855399353825587 2.0615457255069 4.9730475555356e-06 317.337285832867 336.224570207052 0.943825389195816 0.34597315828926 -1747.95643219089 474.796532133997 -3.68148525503042 0.000272201825543761 GPX1 other 0.0487657043295821 1 1 0.943825389195816 -3.68148525503042 0.0196656821875408 6.47219015898468 5.18518183824975 1.24820890778429 0.212867072744231 -23.8186934059382 9.69541710790607 -2.45669610093571 0.0145527170929888 USP32P2 other 1 1 1 1.24820890778429 -2.45669610093571 3.60088904984082e-08 346.982113798377 72.1585919107337 4.80860427858159 2.35869006746271e-06 -555.646093976923 248.188312634681 -2.23880845990844 0.0258664033484073 GTF2IP4 other 0.000406792435960518 1 0.0275329891574922 4.80860427858159 -2.23880845990844 0.40434144537093 10.519444437272 8.08334816390461 1.30137218191906 0.194076101040137 19.4452330724561 33.2801267231699 0.58428963429752 0.559441032955725 HOTAIRM1 other 1 1 1 1.30137218191906 0.58428963429752 0.597724377634911 4.51057548068193 6.73361546541866 0.669859379978939 0.503432018952975 -9.92765645054953 17.5679320850604 -0.565101026260905 0.572402245380427 TMEM238 other 1 1 1 0.669859379978939 -0.565101026260905 0.00609039427170001 4.88050523852894 1.60234401023612 3.04585357910113 0.00251432191981158 -0.610582667024568 4.60916299577748 -0.132471485079597 0.894695157008466 ZNF529-AS1 other 1 1 1 3.04585357910113 -0.132471485079597 6.96180356642511e-14 8.49722258524229 1.40897896880904 6.0307660890245 4.63927085252927e-09 -12.5554568140943 3.60059159658188 -3.48705385693104 0.000558943505097653 B4GALT1-AS1 other 9.38590356825433e-10 1 6.05935166048847e-05 6.0307660890245 -3.48705385693104 0.258721698181962 22.1713752189416 14.7111340773818 1.50711529799934 0.132770741355922 2.14029957812014 26.6177887077415 0.0804086170200026 0.935962695153288 TWIST2 other 1 1 1 1.50711529799934 0.0804086170200026 0.00426802631937114 35.1785660755553 13.4713787190742 2.61135603186226 0.00944591138214978 -49.4090087268547 31.9973962302133 -1.54415716739478 0.123544799683402 LINC01137 other 1 1 1 2.61135603186226 -1.54415716739478 0.00432648318060003 6.97311845390578 2.18833096013618 3.18650084513352 0.00158302133349975 11.0150116555156 9.03115684131064 1.21966785087048 0.223494629117054 ANAPC1P1 other 1 1 1 3.18650084513352 1.21966785087048 0.574648574452253 -2.75057090591711 2.8428083221347 -0.967554120515472 0.333997784738484 3.15511776488055 11.2569665231862 0.280281349187802 0.779442762881168 LINC01122 other 1 1 1 -0.967554120515472 0.280281349187802 3.35217882781447e-06 12.7022571629432 2.62029104883537 4.84765124415813 1.95201336329287e-06 2.05581401133705 5.95962788510301 0.344956774310669 0.730353486496818 HIST1H2BN other 0.033300544475509 1 0.0228912607113355 4.84765124415813 0.344956774310669 3.5749952229384e-07 66.7073060390674 20.887831390316 3.19359653917898 0.00154491288689078 -170.820290508864 40.898074439566 -4.17673185962046 3.81802474413941e-05 LINC01503 other 0.00382488738902179 0.553079064436035 1 3.19359653917898 -4.17673185962046 0.0249497066067639 56.8979681401389 23.1871176321314 2.45386119322106 0.0146657530020899 -5.31011447886911 38.7637693417922 -0.136986535856412 0.891127583533683 LINC01694 other 1 1 1 2.45386119322106 -0.136986535856412 0.0110607119117099 214.122671502011 145.55421752618 1.47108531199722 0.142250699791771 -489.51420861354 271.459415254605 -1.80326848547293 0.0722865929855933 RPS28 essential 1 1 1 1.47108531199722 -1.80326848547293 0.119957249945535 -150.111222643605 75.9167417359202 -1.97731382052425 0.0488640688827654 -187.676484916162 153.527028178054 -1.222432865036 0.222443586235137 UQCRHL other 1 1 1 -1.97731382052425 -1.222432865036 0.000507440819852745 2.74304980189166 0.913885311944856 3.00152520895004 0.00290037050640785 14.3076141760998 5.78771946350841 2.47206421567412 0.0139599021530534 TPRG1-AS1 other 1 1 1 3.00152520895004 2.47206421567412 0.400224421529282 -14.4700147671698 11.393078792599 -1.27007063065074 0.20498219944803 -2.42811661609061 21.5005034704697 -0.112933011983908 0.910154477065524 RPL13AP6 other 1 1 1 -1.27007063065074 -0.112933011983908 2.02842562166476e-07 345.583544639026 66.0194124410506 5.23457467828271 2.99982772838529e-07 -11.0457440040424 152.535483657792 -0.0724142588935118 0.94231747693993 TRIM26 other 0.0022006389569441 1 0.00366248967358561 5.23457467828271 -0.0724142588935118 0.0183510169319178 8.99897445059857 3.68662686343683 2.44097783256788 0.0151962064332168 -9.60670359120956 11.3553081734284 -0.846009940416185 0.398187369583063 RNASEH1-AS1 other 1 1 1 2.44097783256788 -0.846009940416185 2.30929679896991e-07 41.6863002300222 7.51170642518537 5.54951137204399 6.21078466356483e-08 -39.3554322143652 28.981919270386 -1.35793050305605 0.175486173805342 LIX1L-AS1 other 0.00249773541776586 1 0.000779577690970658 5.54951137204399 -1.35793050305605 0.00741506464615477 7.87057814217751 4.5390584115231 1.73396714221541 0.083890024964285 -13.107535609462 6.97847865466875 -1.87827981686135 0.0612548309973992 ZNF879 other 1 1 1 1.73396714221541 -1.87827981686135 3.12673460043082e-06 14.9308405046933 2.95462719026268 5.05337544915975 7.3478705778577e-07 -10.2446946909765 17.3860119040134 -0.589249262426397 0.556113764904063 TATDN1 other 0.0311547835586927 1 0.00880789246167803 5.05337544915975 -0.589249262426397 1.27084357681817e-08 30.9449603031575 5.95062937071361 5.20028359612768 3.73440512746449e-07 -22.9801789625394 12.184260819245 -1.88605441917678 0.0602731963248991 RNF219-AS1 other 0.000146731599379426 1 0.00453954287294584 5.20028359612768 -1.88605441917678 0.581444953767405 1.61291241855995 7.81077571611354 0.20649836548661 0.836535474497019 -11.9045295537952 13.1356665013867 -0.906275258475732 0.36548508626944 LINC01426 other 1 1 1 0.20649836548661 -0.906275258475732 0.232530056343665 -29.4700094185297 20.725128404525 -1.42194580623662 0.156964403051352 -58.1187478312595 41.4165586530121 -1.40327322504456 0.162449183348385 ZNF37BP other 1 1 1 -1.42194580623662 -1.40327322504456 0.0567327509467994 18.4959269246514 8.82544633282747 2.09574974761936 0.0369507097486537 -20.70569877596 33.5771078546361 -0.616661174798028 0.537930630150719 ZNF736 other 1 1 1 2.09574974761936 -0.616661174798028 0.679036493100668 6.05694562017862 7.5433039983394 0.80295658527245 0.422599550524888 15.2190334771971 27.4465454526845 0.55449723184411 0.579628357049487 MAGI2-AS3 other 1 1 1 0.80295658527245 0.55449723184411 0.770703721713466 -7.0577432899405 15.9837041002972 -0.441558680369293 0.659108685776839 -26.4171576777792 39.7696037813431 -0.66425498788027 0.50700847365189 PINLYP other 1 1 1 -0.441558680369293 -0.66425498788027 0.0825637635465554 1.48076583804964 1.47691159134543 1.00260966650055 0.316809138464925 -6.73461145859928 3.51336579619406 -1.91685462011804 0.05614954693433 SP2-AS1 other 1 1 1 1.00260966650055 -1.91685462011804 0.484356539521263 -41.1937320105974 41.5219068516211 -0.992096344654969 0.321902452904977 -144.793678500235 162.762900051009 -0.88959878728419 0.374351725273299 RPL13AP20 other 1 1 1 -0.992096344654969 -0.88959878728419 0.00526660803945707 -0.856066054834798 2.15035759010212 -0.398104045008693 0.690819790721527 -10.0507419874203 3.17028564046056 -3.17029540150843 0.00167064201981917 C5orf58 other 1 1 1 -0.398104045008693 -3.17029540150843 1.81443820846281e-06 23.0117112490511 4.47745525754748 5.1394620214822 4.87757528322794e-07 1.63037556379224 19.3658436183683 0.0841882024827382 0.932960963472953 FAM133B other 0.0183838879281451 1 0.00589796403247923 5.1394620214822 0.0841882024827382 0.0115883929794618 -8.45619679964779 2.82287400862493 -2.99559837733139 0.00295296155360825 -3.80280968336682 6.38798664835071 -0.595306454553824 0.552059396605398 LINC01759 other 1 1 1 -2.99559837733139 -0.595306454553824 0.00406928525480996 13.6446933235413 4.21971779804745 3.23355588609621 0.00135938602752064 -1.77761924121026 15.7588004572209 -0.112801684749789 0.910263477894938 CCT6P3 other 1 1 1 3.23355588609621 -0.112801684749789 0.365541586565735 1.77511390217916 1.96704309565614 0.902427560483644 0.367514963436524 -2.22704389079901 3.31913124863529 -0.670971927282085 0.502726999722198 MCIDAS other 1 1 1 0.902427560483644 -0.670971927282085 0.0494027374371866 15.7498108395324 13.677585652115 1.15150518813216 0.25038408106345 85.1551009564292 36.619599859088 2.32539681711722 0.0206756215443568 MAPKAPK5-AS1 other 1 1 1 1.15150518813216 2.32539681711722 0.0129102896491326 41.0713862234031 14.9524159365912 2.74680602770647 0.00635864280266725 102.280367455386 73.8125634301724 1.38567694579723 0.166810537653189 JRK other 1 1 1 2.74680602770647 1.38567694579723 6.29471773262618e-05 9.96801383137563 2.30643668815564 4.32182417257099 2.06849570515428e-05 0.455296872438808 8.5730197182468 0.053108109791204 0.957678908254378 SDCBP2-AS1 other 0.554573848490172 1 0.22712082842594 4.32182417257099 0.053108109791204 0.0198069084724305 39.912807949064 14.5976661656841 2.73419103410449 0.00660489946247033 25.9892744303938 32.7486697908723 0.79359786508451 0.428023196849754 LINC01287 other 1 1 1 2.73419103410449 0.79359786508451 0.0054673928278349 470.747646258051 148.121498145453 3.17811831605824 0.00162804040942954 291.551953638052 476.854902650358 0.611406010544523 0.541367643973011 GAS5 other 1 1 1 3.17811831605824 0.611406010544523 0.486570054753286 4500.68970888057 4023.98071967745 1.11846701622401 0.264206500958294 254.264021243482 9422.64944585994 0.0269843447646456 0.978489040691176 HLA-B other 1 1 1 1.11846701622401 0.0269843447646456 7.97779782692829e-07 501.224876713908 119.326059069434 4.20046451397724 3.47732780545429e-05 -909.841422504793 437.44231270283 -2.07991178741522 0.0383470819690918 HNRNPUL2-BSCL2 other 0.00831605645479005 1 0.375899135769608 4.20046451397724 -2.07991178741522 0.497121196383573 -1.01172790920836 6.98071126958475 -0.144931923143205 0.884856147998562 -34.1046210809986 28.8247468575758 -1.18317157300672 0.237622164334869 APOC2 other 1 1 1 -0.144931923143205 -1.18317157300672 5.76766322255466e-12 104.896431059034 14.9815881344099 7.00168968189069 1.49373500721265e-11 -94.9813327723064 53.1522040251146 -1.78696884756514 0.0748889507937723 GTF3C2-AS1 other 7.46566327527476e-08 1 2.05971120144552e-07 7.00168968189069 -1.78696884756514 8.01421253562322e-16 14.8007961396014 15.1621903672602 0.976164774422092 0.329724810193944 -148.106721905328 21.4931385537787 -6.89088387602144 2.98314123061897e-11 SEMA3F-AS1 other 1.11485710583055e-11 4.56659259583152e-07 1 0.976164774422092 -6.89088387602144 0.0486518982562307 5.67408083455338 50.2725631607769 0.112866352495437 0.910208406328651 -267.93851348314 114.361602672606 -2.34290624843893 0.0197561782578093 ANKRD65 other 1 1 1 0.112866352495437 -2.34290624843893 0.00443173343815183 44.7233112492318 25.0246755947676 1.78716847216924 0.0748566203594973 -106.041676239204 56.626566045904 -1.87264889333466 0.062028563860296 ZSCAN31 other 1 1 1 1.78716847216924 -1.87264889333466 0.771773594211918 2.45458744275292 89.952799076012 0.0272875048688451 0.978247432075074 -173.774387724418 245.480759118436 -0.707894127215804 0.479526279155504 C12orf75 other 1 1 1 0.0272875048688451 -0.707894127215804 0.296594417284287 1.39513876463422 3.00457020354737 0.464338880478492 0.642720716878602 -8.60392856645414 6.65570408994198 -1.29271500808702 0.197042232261377 SMIM1 other 1 1 1 0.464338880478492 -1.29271500808702 2.71574569995171e-11 146.675387578051 20.2403927752283 7.24666705863353 3.23763238455757e-12 108.089554318488 99.7330211081021 1.08378903113071 0.279276806140466 HGH1 other 3.45714427603853e-07 1 4.51164072788097e-08 7.24666705863353 1.08378903113071 7.74622736547898e-06 31.7947460937499 8.18650823933395 3.88379821582354 0.000124964602351615 -39.576205357143 18.7563601717925 -2.11001521588721 0.0356330117819415 NUCB1-AS1 other 0.0747123629400447 1 1 3.88379821582354 -2.11001521588721 0.492971561042862 4.91112878785872 7.13452495851616 0.688361007413188 0.491724183462811 -15.2146802661154 19.5682259192972 -0.777519655019486 0.437426674226068 PPP1R3E other 1 1 1 0.688361007413188 -0.777519655019486 0.446031070344371 9.87736407827445 7.81330320584602 1.26417263199054 0.207120833100605 14.4861699103568 48.3510676568217 0.299603930427646 0.764680714008922 TSPY26P other 1 1 1 1.26417263199054 0.299603930427646 0.00323790621612345 -0.769196169761859 5.24700934897121 -0.14659706484279 0.883542380887561 -22.3004357995322 7.51602477093023 -2.96705192960296 0.00323322316348393 ITGA9-AS1 other 1 1 1 -0.14659706484279 -2.96705192960296 0.00417005552252532 5.29421816348255 2.59599677189387 2.03937779152947 0.0422335174037088 -7.0523110538406 4.33993658350544 -1.62498020838459 0.105151246119891 SSR4P1 other 1 1 1 2.03937779152947 -1.62498020838459 0.393466150966792 5.56461525168859 5.84664745379065 0.951761722537382 0.341936155736238 13.9620160083536 10.7593562284102 1.29766277014667 0.195337883826521 RPEL1 other 1 1 1 0.951761722537382 1.29766277014667 1.96536355010129e-18 21.2886843057467 2.64516256041905 8.04815727558691 1.82591880342547e-14 -17.7359906079751 6.55577079258473 -2.70540126693209 0.00720080368788863 SMIM27 other 2.81361445832501e-14 1 2.61763719659075e-10 8.04815727558691 -2.70540126693209 2.94306830858825e-05 71.3013161342445 15.6736295270354 4.54912603435324 7.68107777746405e-06 109.450876967924 72.500949945384 1.50964748807257 0.132129467385416 MSC-AS1 other 0.269173027503482 1 0.0869190761297832 4.54912603435324 1.50964748807257 0.0556613917696805 -35.4074388643732 20.2440931922525 -1.74902568013882 0.0812483420713661 -106.409380258305 52.6982977860688 -2.01921854649421 0.0443005755807583 NFAM1 other 1 1 1 -1.74902568013882 -2.01921854649421 0.00402510582285691 1.2646465092352 1.77762437436514 0.711425049899452 0.477339150308499 -10.3658168038207 3.76668637045167 -2.75197236625192 0.00626151186354454 FAM21EP other 1 1 1 0.711425049899452 -2.75197236625192 0.960491630876889 -0.650090246057684 2.84346225663453 -0.228626296881858 0.819306336723807 0.833001772391313 8.38743962006294 0.0993153823007863 0.920950442923905 DICER1-AS1 other 1 1 1 -0.228626296881858 0.0993153823007863 0.306366273807214 58.9735694064462 38.2726693977858 1.54087944045675 0.124337484564036 69.1924892597877 72.2009819253878 0.958331693207315 0.338621274923726 MFRP other 1 1 1 1.54087944045675 0.958331693207315 0.497967504860181 41.8706768922974 47.4893378276287 0.881685843762968 0.378610564099568 -122.669597484876 150.076841560343 -0.817378592256371 0.414322158155771 KIAA0040 other 1 1 1 0.881685843762968 -0.817378592256371 0.515471718187408 -2.08325629173086 1.86960111120067 -1.11427848392376 0.265995937324154 -2.96656861371808 4.21686696517007 -0.703500641168183 0.482255351153462 IFITM4P other 1 1 1 -1.11427848392376 -0.703500641168183 1.49554237579634e-09 5.22175395934008 2.781056326333 1.87761531828638 0.061351812033751 -21.8546797236448 4.57014323459622 -4.78205574788197 2.66157894733494e-06 BHLHE40-AS1 other 1.79465085095561e-05 0.0396335721047645 1 1.87761531828638 -4.78205574788197 0.285262318298212 -3.80682248639123 15.2613695751598 -0.249441733760737 0.803179646303299 -54.3674559394563 35.1719114298457 -1.54576347230654 0.123153149531471 B3GALT4 other 1 1 1 -0.249441733760737 -1.54576347230654 1.61774387171888e-05 28.8272790246848 6.13849470039946 4.69614790460092 3.94442598147447e-06 -4.00701318081942 12.2648128499263 -0.32670805742001 0.744102960253468 GSN-AS1 other 0.151631133096211 1 0.0454634538624747 4.69614790460092 -0.32670805742001 0.0401783667302591 7.9860925244509 4.27564766397299 1.86780884490143 0.0627112550088152 -35.2517095754614 24.3565702970962 -1.44731828600943 0.148795979021298 LINC00941 other 1 1 1 1.86780884490143 -1.44731828600943 0.297308434225603 1.51341555268746 3.64190900485547 0.415555564587072 0.678015512408371 -7.3880949889345 6.03601831492429 -1.22400142005321 0.221857769924024 TSPEAR-AS1 other 1 1 1 0.415555564587072 -1.22400142005321 0.143075929996991 16.4569024310182 10.6880621665738 1.53974613681479 0.124610476547873 82.0394737106333 65.6031996208186 1.25054073863493 0.212015715234306 TM4SF19-AS1 other 1 1 1 1.53974613681479 1.25054073863493 0.00981106662711805 26.4171722616894 9.51459087080952 2.77649061534916 0.00582170337897228 -17.2779130227772 27.431046522896 -0.629867074460895 0.529235280783005 TTC28-AS1 other 1 1 1 2.77649061534916 -0.629867074460895 1.05416102847739e-11 5.95523961284674 0.919057705284318 6.47972328462709 3.4692576404893e-10 -5.40592800386255 3.36308386287461 -1.60743181683308 0.108945873746728 UBOX5-AS1 other 1.35491316990198e-07 1 4.66476382340191e-06 6.47972328462709 -1.60743181683308 0.00807459374617552 22.9733246382592 8.22309835511987 2.7937553031888 0.00552697062279375 -16.2097871752774 22.9448674000325 -0.706466805524205 0.480416811357774 MORC2-AS1 other 1 1 1 2.7937553031888 -0.706466805524205 0.00063007096496988 37.2594926125893 14.0377461792705 2.65423609579223 0.00838154887382915 -58.0512164635067 28.7431043184059 -2.01965716091192 0.0443259581611779 MYCBP2-AS1 other 1 1 1 2.65423609579223 -2.01965716091192 0.782286432900937 1.51303082600961 3.20549840813695 0.472011098857164 0.637243609600959 -5.96761808671641 14.3435767608354 -0.416048115907238 0.677656316917759 ELFN1-AS1 other 1 1 1 0.472011098857164 -0.416048115907238 1.92321414557546e-06 20.5961361428546 4.13263844828829 4.98377402247355 1.02465343356678e-06 -10.8241629428145 8.56379732070894 -1.26394431552456 0.207172828157149 COX10-AS1 other 0.0194571575107869 1 0.0122107949678153 4.98377402247355 -1.26394431552456 6.01198253362161e-16 127.901966983144 16.7803989025145 7.6221052745044 2.87846307528584e-13 -50.3280631148716 38.6727220679693 -1.30138403566259 0.194066130481946 ZBTB22 other 8.37649526409498e-12 1 4.06841971060901e-09 7.6221052745044 -1.30138403566259 2.87785362619059e-59 92.1907036940813 4.5189997639218 20.4006878756891 7.54461829169778e-60 26.5669403987454 22.356801625833 1.18831579057568 0.235590186528839 TMEM147-AS1 other 4.41606638938946e-55 1 1.15787256922686e-55 20.4006878756891 1.18831579057568 0.00480665148053336 4.18143711811937 1.64541320884579 2.54126871939513 0.0115197907911306 -8.07361776713213 5.27320048413433 -1.53106596106549 0.126747253730827 LINC01376 other 1 1 1 2.54126871939513 -1.53106596106549 0.00161478158174653 27.857708019129 7.74977062982083 3.59464935799952 0.000376022861681264 21.4541662255887 17.0536614199712 1.2580387107055 0.209294944563825 CLEC2L other 1 1 1 3.59464935799952 1.2580387107055 1.78819448738822e-06 79.9502393732778 36.9845281086829 2.16172122403011 0.0313877751714703 -246.581642608444 76.6328101767578 -3.21770325321086 0.00142580770375349 ZBED5 other 0.0181197747407048 1 1 2.16172122403011 -3.21770325321086 0.657932855420009 1.69825969582572 2.70983284073962 0.62670275092031 0.531306583253671 -8.50178741923018 14.236111279886 -0.597198718953695 0.550802375174235 TRHDE-AS1 other 1 1 1 0.62670275092031 -0.597198718953695 0.0623592960979857 -5.04292172574787 2.46169267864089 -2.0485586074587 0.041349873108635 12.4159138161935 10.0257202279084 1.23840617271879 0.216505489313318 PPIAL4G other 1 1 1 -2.0485586074587 1.23840617271879 0.0242149856272119 2.08684890222026 0.88988151361143 2.34508625058537 0.0196352481535677 -2.66633894856571 2.13763735160224 -1.24732988341881 0.213191506423374 LINC00854 other 1 1 1 2.34508625058537 -1.24732988341881 1.01687429974753e-10 25.8954457074074 5.25259663900945 4.93002746776514 1.33412650506403e-06 -68.9412280826318 16.8459452824303 -4.09245233359122 5.43232756795484e-05 VLDLR-AS1 other 1.27119456211438e-06 0.782798402542293 0.0158080649585037 4.93002746776514 -4.09245233359122 0.187247429520688 3.27051621442751 2.31314327849844 1.41388397546672 0.158371130251881 -2.92670074839646 5.4066619152098 -0.541313807723614 0.588669134361148 KCNMA1-AS1 other 1 1 1 1.41388397546672 -0.541313807723614 0.00325346494785467 2.78873581267588 2.26596412828519 1.23070607246828 0.219345211278154 -14.896834610584 5.33236783173314 -2.79366223048836 0.00552852255581869 RNF217-AS1 other 1 1 1 1.23070607246828 -2.79366223048836 0.675759883182986 -1245.369060472 1480.46877179897 -0.841199141916858 0.400864532767187 -1721.28244761798 2711.45064603717 -0.634819759722961 0.525999588962483 RPL13AP5 other 1 1 1 -0.841199141916858 -0.634819759722961 0.00833712064891568 47.9254454011907 15.4001891865227 3.11200367870363 0.00202683456308961 21.2769737812066 73.671430378787 0.288809022328051 0.772915702324897 ZNF853 other 1 1 1 3.11200367870363 0.288809022328051 6.82896336852332e-10 57.2443197698339 8.60650017849771 6.65128897723744 1.26842623267787e-10 -10.9967491116186 16.4252167979564 -0.669504046545482 0.503659804363995 PITPNA-AS1 other 8.30811683414547e-06 1 1.72036649938099e-06 6.65128897723744 -0.669504046545482 0.0002067139684999 11.4241465799284 4.71682821257547 2.42199759352495 0.0159942568875461 -18.9455386539438 8.56643079680044 -2.21160237015163 0.0277049518551046 ARHGEF38 other 1 1 1 2.42199759352495 -2.21160237015163 9.45767006245972e-07 5.14427046412976 1.35118619772606 3.80722543849781 0.000168419332466953 -4.90131151746322 3.06254808976565 -1.60040311982114 0.110495936769127 MKLN1-AS other 0.00981422422381445 1 1 3.80722543849781 -1.60040311982114 0.73218858836406 -1.35432013964605 9.23499471685939 -0.146650884073989 0.883500222426412 15.73849569698 21.9683406960853 0.71641713476269 0.474257963923252 CTAGE9 other 1 1 1 -0.146650884073989 0.71641713476269 0.0291717981763341 3.74335293822695 2.07512564093782 1.80391628553884 0.0721966295545702 -4.38203965065393 3.83625062870164 -1.14227147149064 0.25420595429995 INTS6-AS1 other 1 1 1 1.80391628553884 -1.14227147149064 2.42621941424286e-05 23.8132658419274 8.15323664295844 2.92071319461747 0.00374040688930507 -42.8861443402117 15.8542235808619 -2.70502961696471 0.00719550037796752 ELOA-AS1 other 0.223454808051767 1 1 2.92071319461747 -2.70502961696471 0.628111303928796 10.0958458788535 14.2712672957422 0.707424622469618 0.479817513650078 39.2115743225421 51.9513053060439 0.754775536274741 0.450938788495661 BCYRN1 other 1 1 1 0.707424622469618 0.754775536274741 0.00537265491566382 -14.8149833164805 37.7611210666042 -0.392334308357778 0.695075705904815 -200.219967926472 62.9140435313949 -3.18243680882727 0.00160563979233351 CBR3-AS1 other 1 1 1 -0.392334308357778 -3.18243680882727 1.39158175044013e-08 46.906930011443 8.22487447330021 5.70305725196335 2.71065791334752e-08 -37.0745332080493 25.6832031496253 -1.44353229587681 0.149864339759931 NIFK-AS1 other 0.00016036588092072 1 0.00034522939184394 5.70305725196335 -1.44353229587681 0.174691100471612 -1.44335112138199 1.92520359475851 -0.749713497996582 0.453978086996976 -7.30243085185291 3.89959483897549 -1.87261270808621 0.0620335806689952 EDRF1-AS1 other 1 1 1 -0.749713497996582 -1.87261270808621 0.00104668013677662 20.3071093671647 5.75479538726531 3.52872830406828 0.000478927970238275 -6.24244475646043 14.9805633740149 -0.416702937039638 0.677175957731267 NDUFA6-AS1 other 1 1 1 3.52872830406828 -0.416702937039638 2.51283504539606e-20 241.510770328782 24.798368700852 9.73897812562502 8.4494125573985e-20 -51.6365294761388 67.7733853130025 -0.761899811226225 0.446680970743875 PRMT5-AS1 other 3.65441600651948e-16 1 1.25313237638777e-15 9.73897812562502 -0.761899811226225 0.0595099845479677 -1.23885216248559 1.25555778457428 -0.986694660895796 0.324556901191211 6.68416792211005 3.69934851614601 1.80685001505985 0.071748949032281 EIF3IP1 other 1 1 1 -0.986694660895796 1.80685001505985 0.131646623453453 11.5861106100759 6.09651861949741 1.90044701463259 0.0582758178448858 1.35958113175649 14.3605290303704 0.0946748639190921 0.924632524290619 ZNF503-AS2 other 1 1 1 1.90044701463259 0.0946748639190921 4.40797592801122e-05 103.800015238458 24.7742707611687 4.18983130680699 3.61782344626075e-05 6.10676890122623 66.7352665888097 0.0915073725389182 0.927146883399689 B3GNT9 other 0.395748078816847 1 0.390544041023848 4.18983130680699 0.0915073725389182 0.853117782203594 -2.61785178292895 10.2112873247187 -0.256368438149012 0.797831608707961 5.10118648880194 14.212216896241 0.358929681839513 0.719885139257112 NR2F1-AS1 other 1 1 1 -0.256368438149012 0.358929681839513 0.00180879339355039 63.313726986874 28.8134316429119 2.19736849714841 0.0287127325733449 -78.589123622611 43.0259590129476 -1.82655135238151 0.0687016906542027 CDKN2AIPNL other 1 1 1 2.19736849714841 -1.82655135238151 0.0081476809251889 9.45067469174067 3.05830330848113 3.09016920118176 0.0021771653594062 0.712844427377088 15.9841780488229 0.0445968773120357 0.964456622623795 LINC00987 other 1 1 1 3.09016920118176 0.0445968773120357 2.97611671716029e-07 258.177329153176 104.632060754697 2.46747820210151 0.0141314724410675 -779.755575437847 211.701093395184 -3.68328553685016 0.000270364203326882 CKMT1B other 0.00319694457757359 1 1 2.46747820210151 -3.68328553685016 0.0557588503696534 7.65579495216124 3.38343529586108 2.26272834640181 0.0243266657234769 -3.93581419303079 8.199263883343 -0.480020432203248 0.631542871222579 LINC01343 other 1 1 1 2.26272834640181 -0.480020432203248 0.000368498213782568 31.8206899826307 10.9160730830315 2.91503086692361 0.00380816591906511 -63.351531507798 33.4965695698531 -1.89128416197026 0.0594922052671582 SMG1P1 other 1 1 1 2.91503086692361 -1.89128416197026 4.77394015699352e-05 47.2180184027318 13.1359847477256 3.59455490467947 0.00037700625426724 -48.7000200066238 29.7972030126926 -1.63438226016983 0.103177557850336 RNF223 other 0.42693346823993 1 1 3.59455490467947 -1.63438226016983 2.72836391349519e-12 76.2191800234192 15.4809510441403 4.92341715997279 1.36873378176828e-06 -82.5427619121025 31.1409601729314 -2.65061711179513 0.00843652409907544 PITRM1-AS1 other 3.55696803402368e-08 1 0.0162112829112635 4.92341715997279 -2.65061711179513 0.851615073400219 3.03430177798091 5.35394047793347 0.566741784016266 0.571286921506005 1.54823711396987 13.3434355475162 0.116029871651612 0.907701647588063 FOXD2-AS1 other 1 1 1 0.566741784016266 0.116029871651612 0.33016533920491 4.55673752736242 7.11992631548831 0.639997849057783 0.522645193593806 -23.8742854229303 21.6246950700675 -1.10402876644381 0.270434129728037 CECR7 other 1 1 1 0.639997849057783 -1.10402876644381 0.161383275467384 2.02657317278021 3.98476508144008 0.508580338203478 0.611399059914878 -14.2490216777812 9.01095020520449 -1.58130067898404 0.114803375391234 ZNF737 other 1 1 1 0.508580338203478 -1.58130067898404 6.02203734958019e-16 316.890932391649 40.2926046212548 7.86474181479162 5.77138866804247e-14 -74.6060442636905 92.8598127472922 -0.80342660680054 0.422326443531463 RGL2 other 8.38990243543512e-12 1 8.23692590703021e-10 7.86474181479162 -0.80342660680054 0.0170941379869666 27.382411355166 11.5438363219236 2.37203738787966 0.0182814895012415 -17.440605168932 26.6302809116657 -0.654916304742843 0.512992119507097 UNC5B-AS1 other 1 1 1 2.37203738787966 -0.654916304742843 0.229988106496572 9.34250976596604 5.70356469893676 1.63801241137979 0.102414413710208 19.1287286533194 21.0834693643443 0.907285623763105 0.364947119393764 DGCR5 other 1 1 1 1.63801241137979 0.907285623763105 0.0853880969781433 7.14903889608635 5.17877266890642 1.38045041810958 0.168414526735694 -13.3198758699647 12.0927382202241 -1.10147723595706 0.271519396514132 LINC00857 other 1 1 1 1.38045041810958 -1.10147723595706 0.11465279145649 32.0767506731808 16.3794541606713 1.95835284610402 0.0510909573649096 -17.2034269068082 39.7920145079001 -0.43233365084828 0.66580146623106 PYY2 other 1 1 1 1.95835284610402 -0.43233365084828 0.0351235852657205 5.05693988131623 1.96955264839684 2.5675576052422 0.010698538633407 -0.113863048848804 4.93046527021275 -0.0230937736316092 0.981589956405717 OXCT2P1 other 1 1 1 2.5675576052422 -0.0230937736316092 0.0257572430011705 160.987957559574 60.6534214711104 2.65422714259003 0.00834749553177705 62.3421321684921 139.784097186877 0.445988731358668 0.655907941219623 KIFC1 other 1 1 1 2.65422714259003 0.445988731358668 0.268789371556636 4.18403535934999 11.2639349638456 0.371454147487508 0.710545892178985 77.0136479327396 48.205909303163 1.59759766066038 0.111122592666701 C2orf74 other 1 1 1 0.371454147487508 1.59759766066038 0.000193505520876846 74.1694064148403 18.1093236901156 4.09564750644572 5.33823529024034e-05 19.8680757254468 27.2301878269079 0.729634178498534 0.466147564972043 P4HA2-AS1 other 1 1 0.567988234881572 4.09564750644572 0.729634178498534 2.89266000812852e-06 7.21568125814195 1.4030263589048 5.14294062427629 4.7223049724045e-07 3.67136377191467 5.8057095394853 0.632371245399946 0.527595885045591 DCTN1-AS1 other 0.0288861028411714 1 0.00571446124710669 5.14294062427629 0.632371245399946 0.0776813957315472 487.617220334815 220.983513504939 2.20657737132013 0.0280534787482696 139.345555026056 431.486316638916 0.32294316100565 0.746949203967027 AMY1A other 1 1 1 2.20657737132013 0.32294316100565 0.00218302531672164 29.6985616201853 16.2761322074375 1.82466947562728 0.0689861162576343 -44.8880950847751 30.538691667936 -1.46987616800576 0.142580858592931 FAM200B other 1 1 1 1.82466947562728 -1.46987616800576 0.0994795009339441 17.2874939180386 8.59024593260363 2.01245622694285 0.0450093604407496 31.8463390516848 35.5463548071698 0.895910121429983 0.370974209156456 DGUOK-AS1 other 1 1 1 2.01245622694285 0.895910121429983 1.09217110793791e-09 54.2997944088896 22.1787823153671 2.44827662929298 0.0149063352433105 -191.223077696653 37.5733313060708 -5.08932987972129 6.23114626580612e-07 LINC00649 other 1.3175952246163e-05 0.00935793546198762 1 2.44827662929298 -5.08932987972129 0.775838267989862 2.99131823245453 4.57647999825825 0.653628603991056 0.513824945244079 -5.70808763460823 20.4928472431878 -0.278540486193577 0.780779097007188 FLG-AS1 other 1 1 1 0.653628603991056 -0.278540486193577 0.331428101056028 19.4952387213737 13.1052482486867 1.48759018916924 0.137872179680787 19.1218064539454 37.0746021486616 0.51576565480786 0.606384553033905 PTENP1 other 1 1 1 1.48759018916924 0.51576565480786 0.0264145556963345 19.4085768982479 13.780430412953 1.40841587066865 0.159987970990442 -34.5633083275828 22.1956536263289 -1.55721065526915 0.120418245987868 LINC01679 other 1 1 1 1.40841587066865 -1.55721065526915 0.0141776836323915 7.44124063548827 8.2598118481615 0.900897111493474 0.368333475225875 -56.9256532027521 20.8391527880326 -2.73166830637391 0.00665790200810048 LRRC37A2 other 1 1 1 0.900897111493474 -2.73166830637391 0.102115393007476 -28.2159171482881 13.2661197500572 -2.12691560756991 0.0341918014420984 -32.2155879604107 37.9913626356808 -0.847971373634132 0.397087725486594 ABCA17P other 1 1 1 -2.12691560756991 -0.847971373634132 0.490464488910564 -13.5095391278248 11.9135750846253 -1.13396180675095 0.257659348668545 -15.7774369229278 29.6418435906154 -0.53226908355737 0.594909006952882 GOLGA2P5 other 1 1 1 -1.13396180675095 -0.53226908355737 0.000288734288610384 6.43351505187628 1.98527204288186 3.24062139238976 0.00133059478738011 -7.40238930831449 3.86912928429782 -1.91319254653903 0.0567012394231872 LINC01410 other 1 1 1 3.24062139238976 -1.91319254653903 0.00271993815683423 -5.43464611948398 1.89233743426984 -2.87192232265962 0.00435294592632426 -9.63812708225911 3.28161276916595 -2.93700925740508 0.00355506588795247 LINC00426 other 1 1 1 -2.87192232265962 -2.93700925740508 6.55727108309286e-09 27.7647935644998 4.44663430271742 6.24400201912989 1.38785053696314e-09 -4.08009443435864 16.6855212813306 -0.244529036016623 0.806981338695091 MAP3K20-AS1 other 7.67528580276019e-05 1 1.83973467179834e-05 6.24400201912989 -0.244529036016623 0.000197417837125384 7.99770808457576 2.73962122889944 2.91927511738132 0.00375725041190641 -4.10509103204877 5.06010524227082 -0.811265939244879 0.417815959175698 CD81-AS1 other 1 1 1 2.91927511738132 -0.811265939244879 0.0194059532067942 2.15532899246061 2.19445435568828 0.982170801080344 0.326769464292346 -7.81170126929317 3.59387428101605 -2.17361561882033 0.0304785550346671 PAXBP1-AS1 other 1 1 1 0.982170801080344 -2.17361561882033 6.25163140515345e-24 470.656314351754 46.8324730422516 10.0497856247552 8.11598796925239e-21 -379.253486084046 97.448760280517 -3.89182463678679 0.000121227597328598 TMEM250 other 9.27367002640463e-20 1 1.20895756789984e-16 10.0497856247552 -3.89182463678679 0.419354069639995 -41.7996260082874 34.5703870946587 -1.20911651622049 0.227510677086511 -74.3033424240773 70.7422689453569 -1.05033869469851 0.294354982370245 LINC00707 other 1 1 1 -1.20911651622049 -1.05033869469851 7.07401474213899e-23 8.93077358223729 0.814581453873744 10.9636348087315 5.98867605759369e-24 6.57774477914486 4.5744602871466 1.43792805407605 0.15143472265446 SCARNA12 other 1.04532715844588e-18 1 9.00157898216907e-20 10.9636348087315 1.43792805407605 2.93193242194165e-05 770.681983955681 209.721511703168 3.67478747266745 0.000279142323867531 -478.621529923906 469.070576047155 -1.02036144316968 0.308330270362193 TXNDC5 other 0.268213177959222 1 1 3.67478747266745 -1.02036144316968 0.000298944305487191 55.2630617547003 16.2299657526386 3.40500174781428 0.000746461013734891 -62.3948004502322 45.293006880977 -1.37758132539524 0.169301320781343 CASTOR1 other 1 1 1 3.40500174781428 -1.37758132539524 0.0380117087754587 61.5786258782687 24.3804803312543 2.52573472883258 0.0120326124271438 -26.9705435539435 100.590482559805 -0.268122220587902 0.788779628266094 RNF103 other 1 1 1 2.52573472883258 -0.268122220587902 0.523858436542368 23.5550874103149 26.704385002733 0.882068147530984 0.378423385225647 -102.168472174569 170.617885419561 -0.598814549385193 0.549733871500906 RBM14 essential 1 1 1 0.882068147530984 -0.598814549385193 1.58667526508116e-19 62.8138117586418 6.58261608508442 9.54237812850303 3.78281129098142e-19 -30.9109434282163 30.4635212023982 -1.01468714738672 0.311023959604162 ALKBH6 other 2.29449110083387e-15 1 5.59364305597422e-15 9.54237812850303 -1.01468714738672 3.03818056015551e-07 20.6746820850896 5.49019174234313 3.76574863963967 0.000197570622857727 -11.5987374524003 7.97203970707184 -1.45492720540657 0.146669631857851 ASB14 other 0.00326209446743897 1 1 3.76574863963967 -1.45492720540657 0.220084527198519 17.6339944234678 10.3686500836223 1.70070301160238 0.0899983922822006 15.548706794574 17.1070018838682 0.908908930982015 0.36410200628501 PCDHA13 other 1 1 1 1.70070301160238 0.908908930982015 0.217869626377585 381.016118437446 509.949050658337 0.747165070599818 0.455516018287439 2589.29232675398 1544.85125010396 1.67607873352191 0.0947056021642205 KLHL41 other 1 1 1 0.747165070599818 1.67607873352191 0.896088984877616 10.3708786980396 22.3328853857101 0.464377017072568 0.642693427787078 15.6716762889201 96.6651974284959 0.162123253309575 0.87131111527626 GATS other 1 1 1 0.464377017072568 0.162123253309575 0.0165420825624843 4.60609702952813 1.73420367372886 2.65603002652173 0.00830272303886177 -4.21474564379213 6.79755952173591 -0.620038063707282 0.535673999247725 MYLK-AS1 other 1 1 1 2.65603002652173 -0.620038063707282 0.0865458004955772 259.767912456203 125.036627239827 2.07753454480145 0.0385519092846602 -193.643693190473 298.132662259296 -0.649521899824766 0.516468498190252 NME1 other 1 1 1 2.07753454480145 -0.649521899824766 0.0807980612406852 28.2803960571654 13.3609608589349 2.11664388180984 0.0350616507707519 -17.1751392629079 25.5033747026765 -0.673445748381898 0.50114984956915 TNFSF12 other 1 1 1 2.11664388180984 -0.673445748381898 0.000242902512688602 45.7485982099404 14.0805515223664 3.24906294595567 0.00128129396337807 -67.2004198700464 29.4412452388642 -2.28252641234542 0.0231161278724275 CDRT4 other 1 1 1 3.24906294595567 -2.28252641234542 0.010674446981275 -96.0935677691982 40.9355669666294 -2.3474346366702 0.0195121387971944 -275.733300123916 114.736334373588 -2.40319077325682 0.0168214728685051 APOBEC3G other 1 1 1 -2.3474346366702 -2.40319077325682 0.00849118793941985 -11.1942166864868 4.76323185333459 -2.35013054815925 0.0193757422160811 -20.0973229374369 6.7520449842957 -2.97647941981732 0.0031387918173958 TLR9 other 1 1 1 -2.35013054815925 -2.97647941981732 0.0987042552663019 80.4923375135368 37.877371261733 2.12507718546078 0.0343461107624365 80.8005807292072 156.736196914025 0.515519594835705 0.606545942876169 WBP1 other 1 1 1 2.12507718546078 0.515519594835705 3.62699761209891e-27 280.03137397801 23.3628132751269 11.9862009202523 4.1162426247954e-27 521.224060187672 175.557635160521 2.96896264130632 0.003240225673213 MRPS17 other 5.4452115150441e-23 1 6.22499372147808e-23 11.9862009202523 2.96896264130632 6.80576147966083e-11 238.465183669083 33.8038079685602 7.05438818877659 1.11169814645084e-11 74.6707358993701 162.484235150807 0.459556804572861 0.646152376345926 GET4 other 8.56437024600519e-07 1 1.53714502709758e-07 7.05438818877659 0.459556804572861 0.000451485719714467 280.151574610296 70.5220271874688 3.97254001030868 8.78985511406719e-05 -38.2591004237509 242.118684019262 -0.158017959575177 0.874542313991775 C1orf226 other 1 1 0.91695768549949 3.97254001030868 -0.158017959575177 8.30729928786467e-09 332.664381768661 56.2009245182426 5.91919767548806 8.35194063809257e-09 -115.90105916126 159.02397217151 -0.728827594850033 0.466641854242359 ADSL essential 9.68215732000627e-05 1 0.000108157631263299 5.91919767548806 -0.728827594850033 0.80254062004524 -1.21738871075984 2.20216559994614 -0.552814334575756 0.580778934555444 -2.72933330019305 5.43256005227532 -0.502402785046053 0.615731939734529 LILRA4 other 1 1 1 -0.552814334575756 -0.502402785046053 0.719484033279311 -1.76785622287193 2.25229042016853 -0.784914861352405 0.43308419146637 -2.40791833567316 5.85315359908745 -0.411388202087943 0.681063288297093 LILRA2 other 1 1 1 -0.784914861352405 -0.411388202087943 0.000440268343653769 9.79971128890878 2.47410538825065 3.96091101674445 9.23169284636383e-05 -9.17484151718887 15.104633012276 -0.607419028964966 0.544009094225459 LINC00888 other 1 1 0.960557640664157 3.96091101674445 -0.607419028964966 0.0917700141544042 229.844714032987 110.196078740837 2.08577942753793 0.037792931871705 31.0529369606257 219.602461139287 0.141405231979298 0.887639077378421 AMY2B other 1 1 1 2.08577942753793 0.141405231979298 1.55649869814021e-17 283.616710039694 35.4395054482118 8.00284051520263 2.26074358428387e-14 -121.789455114925 82.8088976451242 -1.47072909528214 0.142346998427611 LY6G5B other 2.20929425214021e-13 1 3.23896733320351e-10 8.00284051520263 -1.47072909528214 0.996196316656414 11.1919393630841 156.905225689402 0.0713292964839734 0.943180237449164 -7.08161182415111 359.967555415573 -0.019672916954906 0.984316556358243 PSMB9 other 1 1 1 0.0713292964839734 -0.019672916954906 0.000187578967114205 4.19224451217876 1.00130087834724 4.18679799731978 3.66680644884003e-05 -0.27560174971917 6.0824485031082 -0.0453109877672346 0.963887869472414 ERICH6-AS1 other 1 1 0.395611747765351 4.18679799731978 -0.0453109877672346 0.00184881546239404 711.738371419582 199.782213170159 3.56257126260473 0.000423467780813452 471.809982891683 302.413861947434 1.56014668062304 0.119719835490615 PCDHGC3 other 1 1 1 3.56257126260473 1.56014668062304 0.00707235426724028 8.38127822895296 3.2300633029984 2.59477212758425 0.00990109170134598 -3.46327747752952 7.47783147438559 -0.463139278999875 0.643579353038878 SMKR1 other 1 1 1 2.59477212758425 -0.463139278999875 0.0990678370518552 626.008339146427 322.273257047395 1.94247684366303 0.0529591876103337 949.484762146344 554.246850533575 1.71310808754668 0.0876642538797976 UGT1A5 other 1 1 1 1.94247684366303 1.71310808754668 0.850120663367805 5.39319186568372 10.956029277653 0.492257890975538 0.622877779011809 -3.71762102756603 28.1322636337594 -0.132147952115193 0.894951104787366 ZNF542P other 1 1 1 0.492257890975538 -0.132147952115193 1.81266507010501e-08 103.649146466434 17.1554773323703 6.0417524070205 4.31116890961079e-09 0.998338240935065 82.4609646223809 0.0121067979923207 0.990348097211222 COX19 other 0.000208075823397354 1 5.63599111553419e-05 6.0417524070205 0.0121067979923207 8.12427717066222e-08 28.9002226373571 4.92853345208267 5.86385847196484 1.13273476749549e-08 20.8306463307487 19.3886339273528 1.0743741105639 0.283469568125083 B4GALT4-AS1 other 0.000900901095454734 1 0.000146066148268543 5.86385847196484 1.0743741105639 0.224428931901095 -21.371875590849 12.6654933267163 -1.68740964442085 0.0925020848404349 -17.2543581017206 29.2065778117137 -0.590769593512611 0.555093127784348 TCAM1P other 1 1 1 -1.68740964442085 -0.590769593512611 1.27280243784954e-06 60.7622541316611 12.8532626311226 4.72737980040434 3.41370606499898e-06 -89.3543139066044 52.7634251321845 -1.69348964140882 0.0913354277962253 ACAD11 other 0.0130805906537797 1 0.0394897517599082 4.72737980040434 -1.69348964140882 6.62340287433074e-06 29.405535585278 12.3653199261283 2.37806508533136 0.0179980667865339 -107.991663354553 30.5277447077557 -3.53749234961067 0.000464489375054833 PPIL3 other 0.0642337610752595 1 1 2.37806508533136 -3.53749234961067 1.20814640126982e-15 19.0065252439542 2.19224736153784 8.66988168279571 2.22641214533569e-16 -0.652483099985862 12.3110444600315 -0.0529998167177598 0.957765227974699 RPL13P5 other 1.67666557568226e-11 1 3.24032023632156e-12 8.66988168279571 -0.0529998167177598 0.478762297297183 -4.51152941626354 4.86512118086244 -0.927321077635271 0.354460924745402 -15.2201188272233 19.6922092778961 -0.772900521847867 0.440153554231768 LCE1F other 1 1 1 -0.927321077635271 -0.772900521847867 3.22916969186147e-14 6.08038213331359 3.63770652881911 1.67148781385821 0.0957115068058548 -62.3639296992998 8.08423630259887 -7.71426358223243 2.00141556101427e-13 CDKN2B-AS1 other 4.37681660034904e-10 3.06937090437148e-09 1 1.67148781385821 -7.71426358223243 0.000868396247562321 -4.59191035969242 2.19451407306473 -2.09244972089863 0.0371858081881906 -15.6735621365351 4.67927120364619 -3.3495733532867 0.000906086409952844 TNFRSF13B other 1 1 1 -2.09244972089863 -3.3495733532867 0.366079586720918 128.430450005358 98.2527942284498 1.30714297760063 0.19212360466304 -331.702504112843 585.589573451698 -0.566441957218699 0.571499303059993 LINC02067 other 1 1 1 1.30714297760063 -0.566441957218699 0.256824530188798 -133.546626571796 104.033318393161 -1.28369092358564 0.200184705161584 -538.449531950796 427.333267094609 -1.26002250096664 0.20858513005468 AQP1 other 1 1 1 -1.28369092358564 -1.26002250096664 0.00164695101504399 7.11964640657143 2.27258974628304 3.1328339917999 0.00189291494438283 27.1526777156522 13.7630896449391 1.97286208374271 0.049379839120869 AADACP1 other 1 1 1 3.1328339917999 1.97286208374271 1.33175411309744e-24 308.833295250937 27.9502906196427 11.0493768903389 2.93401221774955e-24 -100.610728062682 112.150296125978 -0.897106218512932 0.37033665921131 ISY1 other 1.98165012028898e-20 1 4.41363457916065e-20 11.0493768903389 -0.897106218512932 0.00225129878411088 22.2110381223563 11.1497131207912 1.99207261045476 0.0472125506749132 -21.1921722296834 20.498130777197 -1.03385876790573 0.301982877665957 PNMA2 other 1 1 1 1.99207261045476 -1.03385876790573 1.20290036484405e-08 438.352929318723 71.2041111255719 6.15628679846402 2.28733340151632e-09 156.668142692997 308.507075321531 0.507826741184835 0.611933665596385 LRRD1 other 0.000139043253172323 1 3.01539162321896e-05 6.15628679846402 0.507826741184835 0.0518760179626891 20.9769612796688 8.69713997694304 2.41193787098756 0.0164304772353148 19.9055899243339 12.4632622783076 1.59714122031917 0.111221215560375 KRBOX1 other 1 1 1 2.41193787098756 1.59714122031917 9.99705042160458e-05 711.740639110565 163.810491587644 4.34490265069352 1.8751255364548e-05 410.735307849163 234.173944180476 1.75397527375041 0.0803950055753323 PCDHGC5 other 0.861609362994907 1 0.206545077840497 4.34490265069352 1.75397527375041 0.00244401550568185 51.5706553812244 14.7796002164588 3.48931328492869 0.000552134806008062 18.1288911988818 48.4245858460351 0.37437369638064 0.708374265674217 ARHGEF25 other 1 1 1 3.48931328492869 0.37437369638064 9.98516071507557e-13 543.262723974628 78.92286675365 6.8834641507685 3.09187797135031e-11 -674.596807752026 364.345710420992 -1.85152943607473 0.0650145090319445 TMEM189 other 1.31584447903266e-08 1 4.24081982550409e-07 6.8834641507685 -1.85152943607473 1.4724135162713e-07 48.2731731156004 8.89792440452264 5.42521726651938 1.14873544945139e-07 -21.4826908061059 28.5159612342196 -0.753356712391879 0.451792976915035 RDH14 other 0.00160993693869104 1 0.00142672942821863 5.42521726651938 -0.753356712391879 0.00123000880892518 9.05439589708015 2.63343014259098 3.43825178828238 0.000664477095858509 21.6628676667946 15.2616129569214 1.41943500519518 0.156764187705874 LINC00886 other 1 1 1 3.43825178828238 1.41943500519518 2.59840629949274e-05 25.248902968616 12.8395916813556 1.9664880001815 0.0501062355230924 -80.7945372494384 28.2540038619929 -2.85957833247565 0.00452063522401811 NDUFB2-AS1 other 0.238793538923383 1 1 1.9664880001815 -2.85957833247565 0.459573125285147 6.5842917039416 19.6632298791729 0.334853009622576 0.737955354394386 -87.8394876376061 80.4313407329697 -1.09210522710583 0.27560838594699 PLCXD2 other 1 1 1 0.334853009622576 -1.09210522710583 0.008977950233713 1516.23257199215 495.365321522059 3.06083713598153 0.00239529823160121 242.061970047617 1483.0208811094 0.16322222642377 0.870447145840926 MIF other 1 1 1 3.06083713598153 0.16322222642377 0.000238385681049068 16.7761418011782 4.11442884676074 4.07739261656839 5.76472826387031e-05 0.832612505484753 16.8894471494917 0.0492977951329693 0.960713022387714 HOXA11-AS other 1 1 0.611118843252892 4.07739261656839 0.0492977951329693 0.000987975842155811 19.4540056953397 5.2075425028961 3.73573632563164 0.000221681639482129 4.37066496720744 16.5793565815912 0.263620903844989 0.792242256289267 TPM3P9 other 1 1 1 3.73573632563164 0.263620903844989 2.29781149660016e-17 46.8484030103145 8.09693274810044 5.7859444394305 1.71773408181426e-08 -53.8910844075125 16.1590015684398 -3.33505038533862 0.000953060673147925 NSUN6 other 3.25393086033549e-13 1 0.000220402460037588 5.7859444394305 -3.33505038533862 0.876744888268053 -6.029835679927 11.7617450822332 -0.512665054187868 0.608539328241834 -5.6992747956373 26.9834647384764 -0.211213602510821 0.832855041573444 HLA-DOB other 1 1 1 -0.512665054187868 -0.211213602510821 0.0117261379412098 35.0862849186318 13.0248092090002 2.69380413606266 0.00743905916266732 6.38674302519921 18.2799920132125 0.349384344401407 0.727032034288843 PRICKLE2-AS1 other 1 1 1 2.69380413606266 0.349384344401407 0.0980518941098875 631.200187075909 324.466271165768 1.94534915696502 0.0526112180373791 959.243384397958 558.018405081476 1.71901746548646 0.0865812994342466 UGT1A9 other 1 1 1 1.94534915696502 1.71901746548646 0.000131563676436535 23.7887744114281 6.02586718911524 3.94777609012006 9.70294103418686e-05 -23.780818616684 25.0761765446865 -0.94834308469259 0.343670443299181 YAE1D1 essential 1 1 1 3.94777609012006 -0.94834308469259 7.76865666265016e-11 184.880708134264 29.499592110109 6.26722930419466 1.26100631785323e-09 -199.766450060707 110.544436657454 -1.80711446094502 0.0717362316261978 CRCP other 9.7551021712898e-07 1 1.67385978631838e-05 6.26722930419466 -1.80711446094502 8.3348380882449e-14 28.4900605409099 3.4988935359623 8.14259143585924 8.96314394694131e-15 7.27823298042104 21.1890891757881 0.343489657343912 0.731457819609754 WWTR1-AS1 other 1.12220260020129e-09 1 1.28836231093334e-10 8.14259143585924 0.343489657343912 0.00124902041950168 8.3158523941516 2.72539075136133 3.05125141780049 0.00247021607186806 -10.422662816938 5.69856211634217 -1.82899872005398 0.0683332461876665 CDRT1 other 1 1 1 3.05125141780049 -1.82899872005398 0.0136291472926051 42.7396536576948 15.1606196601943 2.81912313715724 0.00511552935982789 -7.35685860260321 39.1858334771544 -0.187742812894163 0.851197256742445 PDXP other 1 1 1 2.81912313715724 -0.187742812894163 4.86788075245981e-07 114.453674333795 23.6559529266837 4.83826099453775 2.0426077295619e-06 -35.6111161287245 55.1236984492733 -0.64602189494769 0.518729629812211 RPP21 essential 0.00515119141225297 1 0.0239311921595472 4.83826099453775 -0.64602189494769 0.491210609047909 1.33302151637267 16.705294759922 0.0797963481357268 0.936449107623815 -52.815649358264 45.7543456100477 -1.15433077785437 0.249225914062153 CD302 other 1 1 1 0.0797963481357268 -1.15433077785437 0.00318102755701286 26.0017031481509 8.41099269537058 3.09139528351538 0.00216733149119686 -3.88415537599095 19.3776061679234 -0.200445573221555 0.84125945144926 EGFL8 other 1 1 1 3.09139528351538 -0.200445573221555 8.49267886100116e-05 273.475518086831 64.6647144793647 4.22913052796514 3.07085137464687e-05 -86.3120114288746 282.718638978123 -0.305292964556021 0.760342765879298 ATP5J2 essential 0.73699467155768 1 0.333156665635439 4.22913052796514 -0.305292964556021 1.28169719671635e-07 16.7784077424118 5.27636758292437 3.17991638730987 0.00161735399665621 -17.4610637905119 7.5664331490408 -2.30770079462414 0.0216534300343491 PTPRG-AS1 other 0.00140538097619947 1 1 3.17991638730987 -2.30770079462414 0.00248080959505786 43.8075276850403 20.4960817073918 2.13736109713309 0.0333263053591133 -111.37306905112 51.4001690892062 -2.16678409866376 0.0309889087882177 ARHGAP8 other 1 1 1 2.13736109713309 -2.16678409866376 0.470213242258191 0.960766202824489 1.15675101096516 0.830573039242775 0.406836055330145 2.93011291046579 2.53784079381182 1.15456923760169 0.249131043689303 GUSBP2 other 1 1 1 0.830573039242775 1.15456923760169 4.33926861415311e-35 1482.65927362548 131.118422747443 11.3077875904696 3.71044615393874e-25 -600.025982869055 223.322785630114 -2.68681039946757 0.00759180956857599 ARPC4 essential 6.60132934271113e-31 1 5.59201339860108e-21 11.3077875904696 -2.68681039946757 0.000642658308414867 -3.46616408167266 1.90887832940051 -1.81581195002681 0.0703379195990745 -15.384501028391 4.0291545673624 -3.81829507187712 0.000161445816046254 CORT other 1 1 1 -1.81581195002681 -3.81829507187712 1.04772745685627e-07 7.32104503610373 1.26013550596068 5.80972839942515 1.51878136515706e-08 2.0741407285537 6.45483808988745 0.321331178206186 0.748170524605525 PAQR9-AS1 other 0.00115501474843836 1 0.000195208968863636 5.80972839942515 0.321331178206186 0.0946424936468423 688.376529900438 354.521364991082 1.94170675698982 0.0530528083929045 1071.29486877508 609.707276965505 1.75706426550604 0.0798661636956613 UGT1A1 other 1 1 1 1.94170675698982 1.75706426550604 0.276491235960027 -8.73991103354547 5.44322843712682 -1.60564840048469 0.109343732235278 -5.71423362972104 22.0965571286192 -0.258602894399329 0.796108950621309 INMT other 1 1 1 -1.60564840048469 -0.258602894399329 3.8744229350514e-20 1099.53168789276 113.828612485395 9.65953694668672 1.61563485894065e-19 -557.153831576582 497.709183661547 -1.11943651004732 0.263801440950482 ARPC1A other 5.62798675545566e-16 1 2.39194740866163e-15 9.65953694668672 -1.11943651004732 0.493861758665393 3.17724603753308 6.69933799047668 0.474262687156497 0.635637062168235 14.6479207671094 12.8417961969712 1.14064423250731 0.254873624230236 TMEFF1 other 1 1 1 0.474262687156497 1.14064423250731 0.919727325258982 0.615871083827287 9.76600853292262 0.0630627222729836 0.949756178455844 -6.82820585191459 21.7947884748452 -0.31329534855525 0.754261669960772 FABP5P3 other 1 1 1 0.0630627222729836 -0.31329534855525 0.579630406545908 4.37114467078145 4.47005299819837 0.977873119746727 0.328887475479394 9.9795419099862 20.8632190738196 0.478331837223965 0.632745847954067 RPSAP52 other 1 1 1 0.977873119746727 0.478331837223965 0.708234792753025 -1013.35388578414 2258.7163642533 -0.448641494709823 0.653993939431941 5845.23290953545 8248.10884053593 0.7086755306633 0.479041788351054 SPRR2A other 1 1 1 -0.448641494709823 0.7086755306633 1.3130191700459e-06 351.198406007282 177.903840217048 1.97409120330854 0.0492560029703628 -1225.46421512437 301.388950666871 -4.06605554852902 6.0639356415321e-05 ATP5O other 0.0134807678188612 0.8719333058959 1 1.97409120330854 -4.06605554852902 0.064624539602464 39.3133881957749 46.7392480557816 0.841121537703298 0.400907937130647 -160.289624668535 91.5324611588806 -1.75117791698299 0.0808733779375742 PLEKHO2 other 1 1 1 0.841121537703298 -1.75117791698299 1.88543132331332e-16 78.5453851065537 10.9765054887654 7.15577331847061 5.71331284390788e-12 5.03751371711466 20.2978194685269 0.248180043424155 0.804154291422348 C8orf58 other 2.64280908588828e-12 1 7.9323635524817e-08 7.15577331847061 0.248180043424155 0.350432531988965 2.42530003616231 4.57350431946325 0.530293592561194 0.596276167088263 -7.98060943274795 8.37628694227283 -0.952762183023124 0.341429684279195 HOGA1 other 1 1 1 0.530293592561194 -0.952762183023124 1.42506679532733e-08 263.787502429813 47.8604679483417 5.51159471977024 7.61248547686872e-08 -342.58821922468 198.859372504845 -1.7227662689941 0.0859511099926578 PI4KA essential 0.000164153444153755 1 0.000952930931994426 5.51159471977024 -1.7227662689941 0.181291016820835 128.718336541498 76.0359683069399 1.69286114726509 0.0914551598092089 137.40264776182 151.833953373323 0.904953369843307 0.366170905154566 AKAP2 other 1 1 1 1.69286114726509 0.904953369843307 0.000401474085821281 79.4070144346576 67.107517500273 1.18328046383678 0.237576331497378 -415.752553492129 135.8722494504 -3.05987834288338 0.00240155245858128 HYPK essential 1 1 1 1.18328046383678 -3.05987834288338 5.57560442162267e-06 208.742916643129 41.9288056120625 4.9785085359807 1.04930374676394e-06 154.944378251514 262.124907103048 0.591108948645619 0.554864714573294 SDHAP2 other 0.0544402015727237 1 0.0124972076239586 4.9785085359807 0.591108948645619 2.2150965517456e-07 90.397810035199 16.2777372631906 5.55346290295635 5.9323406248259e-08 -64.8857915535765 107.397973385588 -0.604162159751553 0.546167965927405 AMACR other 0.00239762050760944 1 0.000745279952696878 5.55346290295635 -0.604162159751553 0.0747917243438664 55.7431517085817 31.7739808289213 1.75436474292334 0.0803342287250735 -89.5324368200582 88.6587689221607 -1.00985427508772 0.313335299132424 MTFP1 other 1 1 1 1.75436474292334 -1.00985427508772 0.00276851066816818 95.7882713586919 43.6385126101634 2.19503978548487 0.0288809718105071 -182.002680368744 87.4421548084872 -2.08140662552702 0.0381938616028299 SNHG3 other 1 1 1 2.19503978548487 -2.08140662552702 1.15333953735059e-07 216.776242020199 46.767061840651 4.63523329215803 5.20485469890271e-06 -281.218411996817 121.042902643903 -2.32329534284331 0.0207916526776454 ARFGAP3 other 0.00126844282317818 1 0.0595539474648448 4.63523329215803 -2.32329534284331 0.0170131989050344 12.3616612733092 4.30576428232906 2.87095634195343 0.00436505977564837 0.545168326390554 14.9929891054089 0.0363615502257571 0.971016744307993 BGLAP other 1 1 1 2.87095634195343 0.0363615502257571 2.21498094887287e-12 171.35235800805 24.8517011675401 6.89499510930307 2.93749442241079e-11 -160.708196565669 94.2518286103467 -1.7050936722943 0.0891597326745453 C22orf39 other 2.89453710398707e-08 1 4.02994859810536e-07 6.89499510930307 -1.7050936722943 0.425864477278253 84.8192802039622 73.6952241638559 1.15094676983915 0.250635428382267 279.382213277292 322.654049245722 0.865887826080012 0.387217021419032 PEG10 other 1 1 1 1.15094676983915 0.865887826080012 6.33292978591277e-05 37.6902764818962 8.44556621710881 4.46272937929777 1.12248633238756e-05 39.9361768074497 36.5556134674222 1.0924772700926 0.275445160018009 STAG3L5P other 0.557614467649619 1 0.125460297370958 4.46272937929777 1.0924772700926 0.103145099486148 637.260114782168 332.141614222472 1.91863978343684 0.0559221717985109 975.200420354581 571.218491104493 1.70722838203112 0.0887526403517711 UGT1A8 other 1 1 1 1.91863978343684 1.70722838203112 1.72851313061858e-07 600.593980163429 119.557713323426 5.02346493144035 8.53108684130992e-07 -2198.78957298069 1035.90353591718 -2.1225813956064 0.0345712577984333 EIF6 essential 0.00188148654267832 1 0.0102048860795749 5.02346493144035 -2.1225813956064 2.02204908930836e-06 134.736370484969 66.5587401018145 2.02432273025096 0.0437805310477588 -618.19445647232 151.409908533404 -4.08291942357217 5.644196530479e-05 MRPL20 essential 0.0204105635074786 0.812594974493062 1 2.02432273025096 -4.08291942357217 1.01202372168636e-06 193.954317533725 44.0907924669053 4.39897553847116 1.48300881515896e-05 -155.639375206455 91.3898367589042 -1.7030271715776 0.0895339602079918 ARPIN other 0.0104774815906189 1 0.164436017424826 4.39897553847116 -1.7030271715776 0.0921841250125652 19.3159610125824 24.2009317709754 0.798149476035813 0.425390831442476 316.461408654826 159.932680859648 1.97871633836078 0.0487270652549386 LINC01206 other 1 1 1 0.798149476035813 1.97871633836078 0.0662550351744329 787.663580442641 367.526264744519 2.14314909164431 0.0328572500634598 1139.06394100541 632.073156144824 1.80210776226102 0.072472368058565 UGT1A10 other 1 1 1 2.14314909164431 1.80210776226102 0.00072427140238011 16.442074935824 6.96384380964181 2.36106314059759 0.0188236231859074 -12.0028346714728 9.7809306960554 -1.22716692761288 0.220664728662678 LINC00960 other 1 1 1 2.36106314059759 -1.22716692761288 0.0241526945481599 31.4768162486605 148.486280600075 0.211984677112618 0.832253944154078 -491.987837098478 240.989805033171 -2.04152966981636 0.0420180604099396 SERPINB10 other 1 1 1 0.211984677112618 -2.04152966981636 0.27093581630824 -96.6143657174963 78.6895582385329 -1.22779143612203 0.220427636875543 92.7947962118284 180.527371165621 0.514020647465674 0.607592323573513 HLA-DMB other 1 1 1 -1.22779143612203 0.514020647465674 0.00124144709405736 38.0440291897087 12.8456816079223 2.9616201265837 0.00329218594726122 -41.9261057042889 34.6608697430575 -1.20960916489081 0.227333048133251 DECR2 other 1 1 1 2.9616201265837 -1.20960916489081 2.78480274622633e-06 115.425965133854 22.6287666189837 5.1008509247261 5.80434545644448e-07 56.316047178445 45.1867079781632 1.24629674738997 0.213567055981579 GNG10 other 0.027831318645786 1 0.00699539714410689 5.1008509247261 1.24629674738997 0.00804834688570126 3.87191460973982 1.28929710176032 3.00312054099351 0.00288426524085329 0.283359360785963 4.53369174740043 0.0625007999161914 0.950203290489257 CNTF other 1 1 1 3.00312054099351 0.0625007999161914 0.516551366927627 -3.80654815781927 5.00535442254387 -0.760495229004117 0.447522114227104 11.1708460939148 16.2061975815514 0.689294699617343 0.491140474333145 ZNF702P other 1 1 1 -0.760495229004117 0.689294699617343 8.69496706804357e-12 202.937662519314 27.5667195291472 7.36169069028114 1.56550428444478e-12 18.07436542437 124.261111976363 0.145454721407998 0.884444014653329 AP5Z1 other 1.12017260737605e-07 1 2.19186254865114e-08 7.36169069028114 0.145454721407998 0.00403722906905834 28.6647326558226 9.46595690007764 3.02819175688276 0.00266621973654069 75.778735205149 62.4468000319224 1.2134926876383 0.225862308259163 SOX2-OT other 1 1 1 3.02819175688276 1.2134926876383 0.113796509998824 15.5822892831185 17.4477202781592 0.893084542547609 0.372483030142958 -38.047855816082 25.6190394766078 -1.48513982543423 0.138491212699341 EIF4EBP3 other 1 1 1 0.893084542547609 -1.48513982543423 0.0988867949882711 627.007498890228 322.46043107473 1.94444787163644 0.0527201979235721 949.486025927903 554.568753182596 1.71211598287666 0.0878471390225822 UGT1A3 other 1 1 1 1.94444787163644 1.71211598287666 0.581752617393687 -26.560312424547 29.7049863431204 -0.894136496739995 0.371929354948135 -62.8414548367591 85.6206306995147 -0.733952253368711 0.463522048093818 PSG4 other 1 1 1 -0.894136496739995 -0.733952253368711 0.00903905059197296 69.8890577037477 22.6532812398798 3.08516267306619 0.00221191022347466 16.2532040452112 80.3411740265376 0.202302296949788 0.839808959238288 MRPL33 essential 1 1 1 3.08516267306619 0.202302296949788 6.23417068223307e-10 334.863743286218 58.8493279414522 5.69018806160992 2.90970755376372e-08 -351.94641322225 190.418609934453 -1.84827739969008 0.0655023459447633 MICAL3 other 7.59758381043745e-06 1 0.000370027509612132 5.69018806160992 -1.84827739969008 6.5523654425137e-11 260.478801667057 48.631509278526 5.35617350831584 1.63025312991431e-07 -272.250673613442 104.380874425656 -2.60824289039033 0.00952904311628013 PPAN-P2RY11 other 8.25073856521325e-07 1 0.00201222143825323 5.35617350831584 -2.60824289039033 0.235585649548513 18.204364277631 10.9001848479805 1.6700968406975 0.0958872649791959 15.0320787597287 17.395329105634 0.864144545265324 0.388161886317519 PCDHAC2 other 1 1 1 1.6700968406975 0.864144545265324 0.00128485722906555 75.6843267584559 25.2517087206165 2.9971962529674 0.00293795257502377 -161.67999625937 93.2363509309494 -1.73408755968056 0.0838656076172035 STON1 other 1 1 1 2.9971962529674 -1.73408755968056 0.635048978641469 -69.3402622901789 72.9000856932502 -0.951168460651056 0.342236715606202 -10.9302395544703 255.176597303403 -0.04283402032152 0.965860559011298 VSIG8 other 1 1 1 -0.951168460651056 -0.04283402032152 3.9910189511348e-08 181.780943855183 31.9769392468366 5.68475120310855 3.07207643253719e-08 -71.0371061612704 120.995364994597 -0.587106011576911 0.557568279043634 KCTD7 other 0.000449628195034846 1 0.000390243395989742 5.68475120310855 -0.587106011576911 8.1362002572322e-11 112.741049786281 15.9772074358129 7.05636765618829 1.0750260895134e-11 -44.3002718326344 56.0083704815626 -0.790958055943042 0.429557974371037 EFNA4 other 1.02084904627492e-06 1 1.48697608701493e-07 7.05636765618829 -0.790958055943042 5.92310100583229e-07 10.5979711204533 3.36649733879357 3.14807054748817 0.00180135667228145 -18.8744422462826 6.26845162058232 -3.0110214433671 0.00281502536233097 MRPS31P5 other 0.00622754839753207 1 1 3.14807054748817 -3.0110214433671 0.000629455698008351 24.1144516999167 12.6373062299801 1.90819556486721 0.0572606404687425 -44.1014197735121 18.6757353824283 -2.36142882036155 0.0188035098136383 TICAM2 other 1 1 1 1.90819556486721 -2.36142882036155 0.272630952976836 2.33636455120352 2.80547424843296 0.832787737227862 0.405585555448704 8.18775287880505 5.61448964489708 1.4583254038498 0.145731635703039 PALM2 other 1 1 1 0.832787737227862 1.4583254038498 0.625264488126878 -2.01098098158716 9.06622361939892 -0.221810211837736 0.824603114347337 -15.2377460445732 16.7631850990834 -0.909000643642977 0.364033887507901 C4orf48 other 1 1 1 -0.221810211837736 -0.909000643642977 5.0777096295e-12 42.2946647902618 10.4867924907172 4.03313642638591 6.90133221703905e-05 -48.0619373350639 14.9233841002753 -3.22057899281553 0.00141203264297535 NAT6 other 6.58223499272086e-08 1 0.727676468964597 4.03313642638591 -3.22057899281553 0.0843848456068823 122.056360171072 56.3110248680361 2.16753931325365 0.0309308233269501 34.2545825487945 111.477884337121 0.307276934366686 0.75883246535058 AMY2A other 1 1 1 2.16753931325365 0.307276934366686 0.0712610078452104 -172.415336253179 88.8067559128311 -1.94146644003542 0.0530848238072355 -667.40180776637 401.21645110005 -1.66344576832903 0.0972083821045537 TNFRSF6B other 1 1 1 -1.94146644003542 -1.66344576832903 0.788412787235627 25.9878506328361 38.7288718063731 0.671020079354846 0.502693303817603 3.62522753012287 134.168641739655 0.0270199316555456 0.978460731784746 UPK3B other 1 1 1 0.671020079354846 0.0270199316555456 1.65766123512472e-07 156.85200406359 45.8593962375004 3.42028061711218 0.000708257586693008 -249.381096239234 76.3167904201309 -3.26770943676179 0.00120430963933308 IL10RB other 0.00180685074628595 1 1 3.42028061711218 -3.26770943676179 0.462523643443881 -178.187991488575 210.691567342481 -0.8457291088396 0.398337799637435 -565.251824778056 484.843405732271 -1.1658441016112 0.244548411688632 CFB other 1 1 1 -0.8457291088396 -1.1658441016112 0.86694936386728 3.91794136852994 7.79600201435973 0.502557767598488 0.615621980878642 6.1528573162204 33.6191278894608 0.183016565344911 0.854901283434366 WDR92 other 1 1 1 0.502557767598488 0.183016565344911 0.0654572314187734 922.136342862947 452.589091317401 2.03746921999111 0.0424279807983552 -1109.12226425633 1079.13651929499 -1.02778679474302 0.304828809808425 NME2 other 1 1 1 2.03746921999111 -1.02778679474302 0.0256604416086209 5.81046035070357 3.23078617018187 1.798466393205 0.0730543560496666 -20.1314299651708 13.0658466961519 -1.54076734813519 0.124371021491285 DUBR other 1 1 1 1.798466393205 -1.54076734813519 0.00568175615827678 143.975969923016 68.9506224287996 2.08810254137575 0.0375789162697438 -195.194313477592 137.645187677523 -1.41809762310685 0.157135336350513 PLA2G4B other 1 1 1 2.08810254137575 -1.41809762310685 0.0476925187247958 0.485795851438192 9.41146773481328 0.0516174379094155 0.958865730132004 -71.5295509310862 29.4566251569235 -2.42830095267291 0.0157205354613865 CFAP57 other 1 1 1 0.0516174379094155 -2.42830095267291 8.7409092642419e-14 143.725775292323 22.9677185509001 6.25772973374798 1.25719557979157e-09 -196.770938602889 55.0365425899681 -3.5752779761052 0.000404003657472694 TTC4 essential 1.17652638696696e-09 1 1.66905285173129e-05 6.25772973374798 -3.5752779761052 0.507468842438064 25.5820287018914 22.3051819252116 1.14690966375737 0.252281156596792 42.9026392901147 80.1296943636981 0.535414987300279 0.592737161712636 RPLP0P2 other 1 1 1 1.14690966375737 0.535414987300279 0.756923618539705 -7.48470482727141 17.17756007963 -0.435725725456619 0.663331358287184 -27.7615964417534 40.7742184555668 -0.680861522140669 0.496454576847752 TMEM35B other 1 1 1 -0.435725725456619 -0.680861522140669 0.776668961599083 66.2223740004201 108.123483761968 0.612469851102908 0.540661913944563 -25.5026452530045 249.815429743844 -0.102085949131142 0.918752392457572 HLA-L other 1 1 1 0.612469851102908 -0.102085949131142 0.379608674792791 2.72230024392046 3.07188453594726 0.886198752610666 0.376178004144543 -5.72998185588749 6.71413202042448 -0.853421088304015 0.394066188216427 OSTCP1 other 1 1 1 0.886198752610666 -0.853421088304015 2.43422292864392e-06 80.7551405593122 32.0361702913602 2.52074888555237 0.0121963231860113 -199.588059002376 63.9533700624222 -3.12083724137705 0.00196772233392511 JMJD7 other 0.0244444666494422 1 1 2.52074888555237 -3.12083724137705 0.0461366661436915 -29.4786943859786 14.0507605026149 -2.09801415236509 0.0366902258939532 -68.0086983552571 38.0425689652252 -1.78769994259389 0.0747735679763889 APOBEC3D other 1 1 1 -2.09801415236509 -1.78769994259389 0.0492115128106276 37.2682797382309 20.65551093543 1.80427779563202 0.0721279259945355 -23.7535602381414 36.2557074306863 -0.655167473522713 0.512830622546816 TUBA4B other 1 1 1 1.80427779563202 -0.655167473522713 1.54598600816869e-09 101.100597248105 41.509747732109 2.43558688673746 0.0154273234286232 -351.922197281684 70.2850821198133 -5.00706816678068 9.2607710094502e-07 MRPS6 essential 1.85394642099589e-05 0.0138837478973677 1 2.43558688673746 -5.00706816678068 0.470724775419904 31.5122058298632 27.0524169426289 1.16485731743276 0.244944379443756 51.2631814396195 95.9429636003467 0.534308921841916 0.593498825755141 ZNF512 other 1 1 1 1.16485731743276 0.534308921841916 0.828655964273919 -103.617761847182 174.65532645681 -0.593269978930788 0.553422193898398 -9.81962488673399 469.650361454875 -0.0209083728932198 0.983331860317369 GSTA1 other 1 1 1 -0.593269978930788 -0.0209083728932198 1.01264403496952e-13 183.255586155099 61.0433604451194 3.00205599460491 0.00289340852587386 -414.352933681453 86.5310630280316 -4.78848773124657 2.57662820820415e-06 ACY1 other 1.36129737620952e-09 0.0383866070458254 1 3.00205599460491 -4.78848773124657 1.56682539913401e-26 184.205886945659 15.605571706213 11.8038538038515 7.59025004628993e-27 -27.6783352316565 89.4377045364895 -0.309470545729001 0.757169530818375 NFS1 essential 2.34804454314222e-22 1 1.14764580699904e-22 11.8038538038515 -0.309470545729001 7.7732063454054e-11 32.9151876126494 7.90301606956196 4.16488936918912 4.01396641858602e-05 -27.4454497787974 11.1000267351162 -2.47255708781047 0.0139360593587202 FAM86DP other 9.76003788729101e-07 1 0.431621808990555 4.16488936918912 -2.47255708781047 1.76138903701188e-06 791.127159779684 199.030245920038 3.97490922107148 8.71252865794676e-05 -845.990097080053 387.752595345242 -2.18177803897563 0.0298554192271757 DDOST essential 0.0178692917804856 1 0.909448200942545 3.97490922107148 -2.18177803897563 0.0173811743539938 2.93847385983421 1.23834246099607 2.37290891040804 0.0182429107350293 -1.39158701075911 2.74733364351294 -0.506522756726311 0.612840721868961 LINC01011 other 1 1 1 2.37290891040804 -0.506522756726311 0.568780354960037 -16.5968120966965 16.0696348799966 -1.03280579930015 0.302477149756659 -14.1509281475991 64.8334523717262 -0.218265843170961 0.827361547518723 LCE3C other 1 1 1 -1.03280579930015 -0.218265843170961 0.742894030124448 -15.0819075058658 20.6051916667688 -0.731946965103424 0.464740012359564 1.30991550800206 55.4076185963786 0.0236414330950451 0.981153450341271 GSTA2 other 1 1 1 -0.731946965103424 0.0236414330950451 0.684527381159158 63.9766268260292 304.84681509705 0.209864835903442 0.833907137839097 -941.561027003101 1107.60303230542 -0.850088885223874 0.395913240932741 SPRR2F other 1 1 1 0.209864835903442 -0.850088885223874 3.16972642492904e-06 108.439852931985 21.3903512100883 5.06956860441082 6.76038719426723e-07 54.1218037999146 42.7137532484757 1.2670814359271 0.206047543068371 DNAJC25-GNG10 other 0.0315482871073188 1 0.00811990105903437 5.06956860441082 1.2670814359271 0.116128966845317 709.428768469783 392.180674711429 1.80893352022455 0.0714026782497253 1169.57950726108 674.473910092315 1.73406189588712 0.0838731867207377 UGT1A7 other 1 1 1 1.80893352022455 1.73406189588712 1.12657561410181e-10 154.694406619467 40.4991307351598 3.81969696167249 0.000160481598801684 -169.579736191166 58.4564925485607 -2.90095640018589 0.00397795406649961 FLNB-AS1 other 1.40540307859201e-06 1 1 3.81969696167249 -2.90095640018589 0.000234582949219559 83.0370467878381 36.4510284039283 2.27804400654137 0.0233850361327896 -195.358702262504 78.2371403841359 -2.49700719253431 0.0130284820778925 P2RY11 other 1 1 1 2.27804400654137 -2.49700719253431 1.7289696567205e-09 342.772534414996 57.1130105108964 6.00165411258788 5.31979153563374e-09 -220.584487274539 119.358194199188 -1.84808834244277 0.0655179365478595 TMEM141 other 2.07061406088847e-05 1 6.93594420415926e-05 6.00165411258788 -1.84808834244277 0.00292247691209755 4.74723251981549 1.62086594687433 2.92882488460568 0.00364746239910576 -8.1732857581663 6.98048530554971 -1.17087643629423 0.242522342268741 TMEM225B other 1 1 1 2.92882488460568 -1.17087643629423 0.120260689428471 -19.3499149544668 25.0203955730643 -0.773365668738584 0.439876907752175 -94.8981661272926 47.0420712614299 -2.01730416162819 0.0444983795657601 IFITM10 other 1 1 1 -0.773365668738584 -2.01730416162819 2.20142619395457e-07 178.084761584706 33.8125618926328 5.26682249485235 2.55330168271326e-07 -120.322437549009 153.719611505709 -0.782739667179943 0.434358862500602 DBNDD2 other 0.0023839244254334 1 0.00312804989149202 5.26682249485235 -0.782739667179943 0.434146052541461 -55.0431735953432 43.3604196577083 -1.26943359934843 0.20520889821931 -29.7281187986542 62.5864803172865 -0.474992660522615 0.635116226154728 FAM3D-AS1 other 1 1 1 -1.26943359934843 -0.474992660522615 0.000547341694041146 113.577004668064 29.0075476386983 3.91542939385003 0.000110384018457634 -84.9836732703153 179.965200728945 -0.472222812666509 0.637090631481515 ETV5 other 1 1 1 3.91542939385003 -0.472222812666509 0.381060608438935 10.5170332909467 13.0738306143065 0.804433956750066 0.421753095068295 -50.767846148584 44.877337372449 -1.131257982782 0.258807035372482 CFHR1 other 1 1 1 0.804433956750066 -1.131257982782 0.00117454528839156 144.522193160526 39.1625991489475 3.69031158046643 0.000264099037436739 227.702812121102 224.446309145474 1.01450905113132 0.311123483102033 RBM12 other 1 1 1 3.69031158046643 1.01450905113132 0.0984239378568727 642.27587354937 331.042969522121 1.9401586279767 0.0532414375648127 980.703672666985 569.329037506623 1.72256043177066 0.0859372356157985 UGT1A4 other 1 1 1 1.9401586279767 1.72256043177066 0.557323032341168 -4.54966072626951 5.31027617327791 -0.856765369222051 0.392219739941047 -11.3684123315024 13.1000112826232 -0.867816987805368 0.386148934474594 LILRA6 other 1 1 1 -0.856765369222051 -0.867816987805368 0.00496734806922961 93.1183982187223 28.3416201847732 3.28557074760147 0.00113559379205283 75.548683837908 114.961324810117 0.657166085748337 0.511566491202558 SCARF2 other 1 1 1 3.28557074760147 0.657166085748337 0.00375322111610039 -128.854627181942 80.502192375211 -1.60063500607991 0.110447612316683 -709.230394023663 217.960458774871 -3.25394063680247 0.00126019688464746 APOBEC3C other 1 1 1 -1.60063500607991 -3.25394063680247 0.477525422299149 7.41420318395484 6.39836683295002 1.15876494385622 0.24741600967564 2.62283434487466 9.12490816918235 0.287436793471827 0.773963940743336 CCDC13 other 1 1 1 1.15876494385622 0.287436793471827 0.165950219116285 480.13002337362 266.02664332307 1.804819311991 0.0720429159651624 -678.207569056452 1143.85864310303 -0.592912046559029 0.553658793177119 ASPRV1 other 1 1 1 1.804819311991 -0.592912046559029 2.78294559306787e-22 551.447343200207 60.9267194933556 9.0509935178825 1.41532162189969e-17 -996.276985324525 281.266885131242 -3.54210551611738 0.000455967049461124 UBE2V1 other 4.09788738579243e-18 1 2.07372924040742e-13 9.0509935178825 -3.54210551611738 0.000123842363227875 26.6559864623657 13.8078102985692 1.93050062870055 0.0544393715615752 -77.063106237975 32.1600731147067 -2.39623541784594 0.0171455163922333 CTAGE8 other 1 1 1 1.93050062870055 -2.39623541784594 0.733956761415136 -3.35567062805034 4.26555142464562 -0.786690932539662 0.432054257528366 -2.30884495765733 9.96953310156666 -0.231590078906956 0.817006781024871 PTCHD4 other 1 1 1 -0.786690932539662 -0.231590078906956 0.536170688285594 97.031251128013 140.987033458866 0.688228191965773 0.49182376606802 353.816528546538 328.509582608707 1.07703563998611 0.282301767435858 C4A other 1 1 1 0.688228191965773 1.07703563998611 0.432408249198185 -8.19096262077521 72.0874124615137 -0.11362542143052 0.909605987183105 152.391322912261 143.328766364566 1.06322915334835 0.288479725963981 HBB other 1 1 1 -0.11362542143052 1.06322915334835 0.234340846831153 1.85703300603335 2.08734763356293 0.889661585915878 0.374320152518082 -7.5919791789897 6.15592731548923 -1.23327953530042 0.218382326828009 CRYBB2 other 1 1 1 0.889661585915878 -1.23327953530042 8.22407452363023e-14 180.428902369545 34.2406802571877 5.2694310105498 2.5339667417304e-07 -201.730712430873 59.9561831888006 -3.36463566727768 0.000860564849290693 N4BP2L2 other 1.10737163460681e-09 1 0.00310461605196808 5.2694310105498 -3.36463566727768 0.00956461308439655 48.6387537286069 22.1244584356214 2.19841556213174 0.0286442008868909 -60.1328684328417 47.5133749165351 -1.26559876115883 0.206589106905004 MIR4712 other 1 1 1 2.19841556213174 -1.26559876115883 0.413051041412259 1.46629879983445 1.24810745241811 1.17481775867423 0.240952140016948 -4.47052467006944 8.61188023095056 -0.519111338079535 0.6040464688902 LIFR-AS1 other 1 1 1 1.17481775867423 -0.519111338079535 3.09502654965549e-05 29.7739323836569 17.0887815074286 1.74230868191006 0.0824242674776277 -95.1442482286936 27.370858940746 -3.47611481373922 0.000579675892149041 LINC00847 other 0.28245212292156 1 1 1.74230868191006 -3.47611481373922 0.942766614530482 6.95185192861717 32.1643009976064 0.216135644581069 0.829021028383906 -11.1006124733144 67.9654140114587 -0.163327372234397 0.870364758079322 IGFBP7-AS1 other 1 1 1 0.216135644581069 -0.163327372234397 0.785345590254923 5.09529043415128 9.84682363745431 0.517455234474837 0.605197036260363 -19.5329200359843 51.1611073656182 -0.38179236224099 0.702869579820576 A2M-AS1 other 1 1 1 0.517455234474837 -0.38179236224099 0.482203343831269 8.42737500007187 7.0486831293247 1.19559566594949 0.232753652340313 7.62384808552145 12.4733261089759 0.611212119278694 0.541499974886255 SMARCA5-AS1 other 1 1 1 1.19559566594949 0.611212119278694 0.000964853992763045 4.54662521358588 1.23011014257665 3.69611228801209 0.000257863063897451 -3.51330063389008 7.23837838241243 -0.485371232101734 0.627748310058441 RNF139-AS1 other 1 1 1 3.69611228801209 -0.485371232101734 0.151421520268164 -2.2833258809334 1.36129573114041 -1.67731803509042 0.0944754124773549 -8.97083409421767 8.1052384013666 -1.10679459998427 0.269229924792471 LINC00861 other 1 1 1 -1.67731803509042 -1.10679459998427 2.13782597558626e-10 12.7619296224627 2.00491286090878 6.36532882365671 6.75142426338639e-10 -16.0086196310314 10.3070839194136 -1.55316671099173 0.121371730319145 ARNTL2-AS1 other 2.6517593401172e-06 1 9.02530395529492e-06 6.36532882365671 -1.55316671099173 0.468949383738224 2.30317507528726 5.57783423759536 0.41291565456778 0.679944941860042 -6.89826002899945 7.66541904835066 -0.899919493701226 0.368839809811361 SCAMP1-AS1 other 1 1 1 0.41291565456778 -0.899919493701226 0.00106721479704769 -7.5210090941996 3.0240685361551 -2.48704981526711 0.0133948035280937 -23.3721173571802 6.47582590670856 -3.60913305791128 0.000356908614933922 BDNF-AS other 1 1 1 -2.48704981526711 -3.60913305791128 0.024102124942328 2.97645421315551 1.15155609033006 2.58472360847173 0.0101937541756191 -3.5944487004027 6.56366923402225 -0.5476279459317 0.584333979474935 DDX11-AS1 other 1 1 1 2.58472360847173 -0.5476279459317 0.506048358196622 7.47657248893969 9.72904221729762 0.768479807359332 0.442772502382654 -15.9967667658606 25.8611265379077 -0.618564189089452 0.536646309753085 ZNF585B other 1 1 1 0.768479807359332 -0.618564189089452 0.0364637621756113 146.508111744026 60.5097257511817 2.4212324535476 0.0160238198431952 -48.7376061272313 180.193610471546 -0.270473553416742 0.786970322412846 CEBPA other 1 1 1 2.4212324535476 -0.270473553416742 0.0799875406482953 -0.373575589880658 2.34416751438093 -0.159363862688506 0.873483059923853 -9.9262740591702 4.68023588505473 -2.12089183172743 0.0347020586017527 RAD51-AS1 other 1 1 1 -0.159363862688506 -2.12089183172743 0.616791088492067 1.13374075402202 6.45411483518712 0.175661695363862 0.860670834298744 8.61329779798333 8.9998633647104 0.957047618273535 0.339265695037281 MEF2C-AS2 other 1 1 1 0.175661695363862 0.957047618273535 1.46313695132852e-06 49.0947691998343 12.5163813136142 3.9224411568888 0.000107297658044387 -34.0774258097923 18.538538822513 -1.83819372907692 0.0669606130756997 LINC01184 other 0.0149591121903828 1 1 3.9224411568888 -1.83819372907692 5.71940047527871e-15 45.1094393132099 6.58841113312259 6.84678572750669 4.03817641114318e-11 -15.8299490801731 18.4312713943396 -0.858863653054051 0.39107722312607 RAB30-AS1 other 7.86017207317553e-11 1 5.52462914808498e-07 6.84678572750669 -0.858863653054051 0.0164962985632329 16.0222966352777 5.57430129483469 2.87431478634361 0.0043209430616246 15.5607761614244 22.5805027374399 0.689124433692244 0.491245887317727 NUDT16P1 other 1 1 1 2.87431478634361 0.689124433692244 6.01597944595276e-25 34.2797858983678 4.44726134655409 7.70806643169939 1.6587745583341e-13 -56.3968018055996 14.3692701546104 -3.92482020302921 0.000106489099744171 KCTD21-AS1 other 8.9668173641926e-21 1 2.35263995608526e-09 7.70806643169939 -3.92482020302921 0.0465071745275389 7.90255404916654 3.67944890226357 2.14775480216751 0.0324933887468582 -6.61831310970543 10.9188089570826 -0.606138740564042 0.544857783169302 LINC01550 other 1 1 1 2.14775480216751 -0.606138740564042 0.886677660808938 7.0051378220399 16.9044659719215 0.414395688907032 0.678868194025656 -22.4270420554774 98.2049393324372 -0.228369796956534 0.819507891608735 CASC8 other 1 1 1 0.414395688907032 -0.228369796956534 3.21453878413156e-08 13.4455946095722 2.2793906837162 5.89876702823545 9.33948246909388e-09 -13.6574504306846 13.024811478331 -1.04857183180011 0.295169004176179 UBR5-AS1 other 0.000364110808078582 1 0.000120768847807853 5.89876702823545 -1.04857183180011 8.86208292975067e-07 31.8986409882652 12.347055420485 2.58350188785434 0.0102277335857133 -72.28870205954 24.9763166697167 -2.89428993936439 0.00406367457750449 SBF2-AS1 other 0.00921213520547582 1 1 2.58350188785434 -2.89428993936439 6.3386044857053e-06 9.08578200161307 1.92375379098654 4.72294429993231 3.4968457646096e-06 -8.68923771135179 8.94895701606596 -0.970977701172561 0.332299662497927 LACTB2-AS1 other 0.0615605267651699 1 0.0404340275761808 4.72294429993231 -0.970977701172561 0.0191282790465484 2.4128690281149 0.882071420608377 2.73545766447201 0.00658352192442375 -1.31360800243562 4.31794677849315 -0.304220517255664 0.761161404817519 CACNA1C-AS1 other 1 1 1 2.73545766447201 -0.304220517255664 0.00733699605536726 245.872660427807 96.5151118785356 2.54750427826513 0.0113171024452541 -481.210004456327 378.073575913298 -1.27279459637952 0.204014891926129 H2AFJ other 1 1 1 2.54750427826513 -1.27279459637952 0.0119148980981231 18.7267646910636 6.64589062187661 2.81779610236433 0.00513619578196833 2.44472482071779 13.2785438129053 0.184110912699763 0.854043060008996 PLA2G4E-AS1 other 1 1 1 2.81779610236433 0.184110912699763 0.0899274366889902 58.992422010151 27.8719019595699 2.11655530705165 0.0350692334081915 53.968147610402 39.4771107219561 1.36707440396306 0.172561544935446 STARD4-AS1 other 1 1 1 2.11655530705165 1.36707440396306 0.125733315829921 0.26899629982555 2.9091124289844 0.0924667940453095 0.926385033607122 -10.6766915447407 5.69710107648795 -1.87405689339156 0.0618336171434832 UBAP1L other 1 1 1 0.0924667940453095 -1.87405689339156 0.441840768776121 -2.82852690923418 4.57622507556311 -0.618091737737818 0.536955896780245 -13.4669924849823 11.132837973503 -1.20966392549992 0.227303559743951 SOCS2-AS1 other 1 1 1 -0.618091737737818 -1.20966392549992 3.15365811926527e-05 251.270161976618 64.7286781845917 3.88189854982133 0.000126125629507003 -248.089265307458 157.232944497158 -1.57784531798259 0.115598493990533 PGAM5 other 0.287392864408644 1 1 3.88189854982133 -1.57784531798259 0.00670001076218111 9.57479296325251 3.0336264898091 3.15622011985234 0.00175129146618825 -6.20554020602235 17.3341273121002 -0.357995536451988 0.720584163958407 BAALC-AS1 other 1 1 1 3.15622011985234 -0.357995536451988 0.000163217559444175 16.728010232817 22.4745556630789 0.744308830109493 0.457235876394763 -123.50039056102 42.3227768645151 -2.9180597236418 0.00377153972043722 MIR210HG other 1 1 1 0.744308830109493 -2.9180597236418 0.00406564263956163 1.07934772273465 3.4600757749479 0.311943377237424 0.755286707713897 -20.1060473519063 6.79824982891586 -2.95753287359148 0.00333196149342329 UBL7-AS1 other 1 1 1 0.311943377237424 -2.95753287359148 0.000296428367246834 30.031273963234 10.4020253208078 2.8870602634624 0.00415573920814859 -25.8196381940271 21.5532405745675 -1.19794692147101 0.231832590968546 ZBED5-AS1 other 1 1 1 2.8870602634624 -1.19794692147101 2.15740064305767e-08 99.2602045393379 18.4101136837696 5.3916127974183 1.3613028026075e-07 -92.0156516327266 69.3583070504615 -1.3266709576083 0.185566465992035 ZCCHC3 other 0.000246569319495061 1 0.00168610965130965 5.3916127974183 -1.3266709576083 8.98165450750723e-07 12.7659476548993 2.4709079281979 5.1665007462297 4.25566491289945e-07 15.8257049555401 5.75278325967233 2.75096492274967 0.00628801213283324 DNAJC3-AS1 other 0.00933373536420152 1 0.00516084483987316 5.1665007462297 2.75096492274967 0.0439549099991983 9.67322559535043 5.67476162855068 1.70460474439716 0.0892387744683125 -7.84399991126582 7.85437486256684 -0.998679086307624 0.318704744222157 CKMT2-AS1 other 1 1 1 1.70460474439716 -0.998679086307624 2.89070955931668e-12 205.569193215247 76.7037710865609 2.68004024187103 0.00774355489913913 -500.473072899437 108.730233754842 -4.60288785939587 6.02342885594531e-06 TWF2 other 3.76659455578964e-08 0.0891889110699823 1 2.68004024187103 -4.60288785939587 3.62345975514697e-10 75.7249800902576 11.9793958180954 6.32126872173902 8.89297549645459e-10 -29.9310459251393 29.2572876515595 -1.02302873327166 0.307081766392041 MARS2 essential 4.45576846090423e-06 1 1.18525577416747e-05 6.32126872173902 -1.02302873327166 1.23270472176597e-05 13.9921630207558 3.12543792288148 4.47686479975125 1.05906166885329e-05 3.36753099415241 7.8344687006943 0.429835273176084 0.667608429378524 LRP4-AS1 other 0.116712483056802 1 0.118583135061503 4.47686479975125 0.429835273176084 0.00289671541120343 3.33290841730076 1.65948938789265 2.0083939322644 0.0454413531375576 -3.6094769070932 3.06529707254483 -1.17752923180675 0.239859363110374 STX18-AS1 other 1 1 1 2.0083939322644 -1.17752923180675 0.0789647568241886 -19.4564760734471 8.88580725512415 -2.18961266149761 0.0292832657611361 3.75468108102776 23.7140548921007 0.158331466217466 0.874296747680931 PCED1B-AS1 other 1 1 1 -2.18961266149761 0.158331466217466 0.000821544599866455 14.0582230704245 7.09786881123945 1.98062593776928 0.0484892607559992 -21.6439643593 9.89753840968689 -2.18680276482855 0.0294806446466288 TMEM161B-AS1 other 1 1 1 1.98062593776928 -2.18680276482855 0.358159266365354 -6.07442542907113 5.11392746187792 -1.18782002176474 0.235787972166594 -11.940181216133 10.1163148353028 -1.18028960254039 0.238764409283604 LINC00926 other 1 1 1 -1.18782002176474 -1.18028960254039 9.28594159890242e-05 12.6498307728167 7.12480444856933 1.7754635743521 0.0767747282443048 -72.4500202471116 19.5293045669545 -3.70981055668025 0.000244607637812166 NRAV other 0.803233948305059 1 1 1.7754635743521 -3.70981055668025 0.161654932665334 2.00968609822311 7.88261730789959 0.254951625801889 0.79892423551084 -23.6992424388271 14.5515313098619 -1.62864250738791 0.104372768034334 FAM13A-AS1 other 1 1 1 0.254951625801889 -1.62864250738791 9.00177468071746e-10 41.7543429353472 10.563402056736 3.95273631649015 9.53130404997704e-05 -79.109398028254 22.6201900374091 -3.49729148594346 0.000537130760859271 UBA6-AS1 other 1.09065502031573e-05 1 0.989921238630615 3.95273631649015 -3.49729148594346 6.01585523793275e-07 141.568315067458 60.6404711307583 2.33455170165476 0.0201870562547286 -652.57372439354 158.343031201929 -4.12126583304659 4.80814418297797e-05 BCKDHA other 0.00632326544059111 0.694007531371041 1 2.33455170165476 -4.12126583304659 0.293595368311771 -145.344310103754 101.970480256829 -1.42535672812053 0.155028763648707 -212.066016813271 184.140962173851 -1.15165042209921 0.250324459934197 ADH1C other 1 1 1 -1.42535672812053 -1.15165042209921 3.02592250070549e-11 128.257614543453 20.0254249087683 6.40473873227503 5.39262437770103e-10 -31.7142476061844 46.6134210233553 -0.680367304306934 0.496765406276822 TRIM39-RPP21 other 3.84655268289682e-07 1 7.22288109149276e-06 6.40473873227503 -0.680367304306934 0.207418129764361 -18.3289614300981 20.3109891997154 -0.902415990175159 0.372238171001469 -54.6130379869814 31.453782053136 -1.73629479261736 0.0902092662782368 TRIM52-AS1 other 1 1 1 -0.902415990175159 -1.73629479261736 0.484756666275247 -10.4949393314338 8.73728502727529 -1.20116710152772 0.230574680315269 -4.76369246624317 12.1413155456157 -0.39235389677055 0.695057944298014 MEF2C-AS1 other 1 1 1 -1.20116710152772 -0.39235389677055 0.77502868597531 2.38414814189902 3.33950512895102 0.71392258728104 0.47579707028875 1.42337278233117 4.66004873923951 0.305441608441944 0.76022904657722 LUCAT1 other 1 1 1 0.71392258728104 0.305441608441944 0.581243262686143 2.59967841396142 2.97486506107235 0.87388112085471 0.382844530209868 -0.743403614873136 5.10254078992538 -0.145692831371566 0.884256477796617 APELA other 1 1 1 0.87388112085471 -0.145692831371566 1.08672784261334e-14 173.956416789335 29.0973755075717 5.97842292491527 6.0658774117429e-09 -266.712806889627 65.34478850282 -4.08162323270993 5.66593780496442e-05 CDK11B other 1.48740439818488e-10 0.815611747024628 7.89837897783044e-05 5.97842292491527 -4.08162323270993 0.0311995368862706 35.7416620262613 14.0143282020956 2.55036570507295 0.0112279736040168 22.3139576538449 26.1498553135331 0.853310941353352 0.394127159220813 LINC00504 other 1 1 1 2.55036570507295 0.853310941353352 0.212018875360215 19.1444502301557 10.9630244161145 1.74627452275079 0.0817319144265448 14.244105170343 17.4956131818945 0.814152954929505 0.416168486760436 PCDHAC1 other 1 1 1 1.74627452275079 0.814152954929505 0.127881609060953 -0.849645198636741 3.29971739438356 -0.257490292981732 0.796965806614389 -9.68485172706856 4.94524507013819 -1.95841694187219 0.0510495302305479 SEMA6A-AS1 other 1 1 1 -0.257490292981732 -1.95841694187219 0.418432685861908 -31.160843030195 35.1947818778187 -0.885382473412457 0.376615195102976 -115.409353142391 120.831952971945 -0.955122799092614 0.340236563063675 PCP4L1 other 1 1 1 -0.885382473412457 -0.955122799092614 3.67648497436728e-05 41.2781185454091 20.4183370774037 2.02161999720781 0.0440502410618447 -69.9872159979974 28.9436950995001 -2.41804703087845 0.016163936541771 ABHD14A other 0.332685125330495 1 1 2.02161999720781 -2.41804703087845 0.0293072504636319 -1.07445184406974 2.67907010179865 -0.401054023688439 0.688648011144528 -13.8356811881081 5.35838553407079 -2.58206153703112 0.0102653748350704 SRP14-AS1 other 1 1 1 -0.401054023688439 -2.58206153703112 0.366252499311709 57.9909028306336 80.6468109298134 0.719072486091271 0.472621023727506 -75.1860399917275 116.340333659334 -0.646259449555012 0.518574547201951 TMEM110-MUSTN1 other 1 1 1 0.719072486091271 -0.646259449555012 1.18569134313537e-07 15.9801159666242 2.79362448498146 5.72020901611272 2.44962568525489e-08 -2.13476830245607 15.6882092060603 -0.136074696252228 0.891848061266428 DSTNP2 other 0.00130283764783715 1 0.000312400763640556 5.72020901611272 -0.136074696252228 9.13647756755607e-19 409.835650574206 43.072007496971 9.51512767551007 5.31516167670275e-19 -253.291252957298 275.19281343332 -0.920413762980301 0.358072256757532 RBM14-RBM4 other 1.31199817870105e-14 1 7.85368289349599e-15 9.51512767551007 -0.920413762980301 2.93504709752677e-11 6.82914818444236 0.944889869782768 7.22745412225913 3.83061502749908e-12 7.69339495272061 6.65862340575949 1.15540322434605 0.24881224398284 OXCT1-AS1 other 3.73308640334429e-07 1 5.33298224128421e-08 7.22745412225913 1.15540322434605 6.5961133382197e-35 4.29133657490042 0.310041489269673 13.8411687577976 1.19078919797005e-33 0.283448287123629 1.74582496053299 0.162357792752084 0.871139561892329 ALG1L9P other 1.00326883874322e-30 1 1.81381010634798e-29 13.8411687577976 0.162357792752084 0.161180083121471 -14.6940270569798 48.2525991534134 -0.304523016682727 0.760928025524114 -252.145649529679 131.65220506925 -1.91524060988609 0.0563557876692205 LY75-CD302 other 1 1 1 -0.304523016682727 -1.91524060988609 0.00576059748617172 3.21693406222607 4.44345226641186 0.72397178350332 0.469613642955415 -16.6526139556525 8.38252522809624 -1.9865867984312 0.0478235008094678 CCDC153 other 1 1 1 0.72397178350332 -1.9865867984312 0.850968532222374 3.61688114297297 10.6259421002954 0.340382161772971 0.733797811829968 -26.4082700037153 65.0753530883593 -0.405810629530633 0.68515990887445 ACTN3 other 1 1 1 0.340382161772971 -0.405810629530633 0.00262736248211316 5.95505426964826 1.78211256059687 3.34157022475268 0.00093814975408784 1.42312017784754 3.78816653586842 0.375675188609758 0.707422999526797 USP46-AS1 other 1 1 1 3.34157022475268 0.375675188609758 0.165812548989234 36.5075965280265 27.7375756744925 1.31617834797289 0.189056195640174 -69.4388346073228 52.9454275960522 -1.31151711791068 0.19062331505142 TNFSF12-TNFSF13 other 1 1 1 1.31617834797289 -1.31151711791068 0.403319370219664 -7.21044437203277 16.4081318585072 -0.439443346397434 0.660638794900064 -47.7303520520663 35.4268440708186 -1.34729336761279 0.178844970753065 FMN1 other 1 1 1 -0.439443346397434 -1.34729336761279 2.97395382024081e-13 216.096433212962 27.7962992907824 7.77428789898741 1.06247270752967e-13 -6.57349697403532 121.527357963149 -0.0540906762412184 0.956896886082944 ATP5J2-PTCD1 other 3.96071169779671e-09 1 1.51147367373171e-09 7.77428789898741 -0.0540906762412184 0.080481387259342 -17.2547848178853 16.0082128614247 -1.07787077591057 0.28190582167649 -53.2676825870913 23.8201033837315 -2.23624900903964 0.0260265274883309 C5orf66-AS1 other 1 1 1 -1.07787077591057 -2.23624900903964 0.130003478739846 -3.65720922174962 3.2913391590959 -1.11116145889815 0.267333029676218 -12.3686215244061 6.35860778593874 -1.94517761447053 0.0526291979411817 ZNF436-AS1 other 1 1 1 -1.11116145889815 -1.94517761447053 0.0708241637450943 -4.05202032799152 1.80214101914892 -2.24844797656575 0.0252321386989495 -1.50839205171376 3.36399820554287 -0.448392644570492 0.654175210080393 LINC02362 other 1 1 1 -2.24844797656575 -0.448392644570492 6.68932540333196e-14 112.797225452733 15.2564260793629 7.39342391632018 1.26946962419457e-12 -155.006424101456 74.8953242121974 -2.06964087186916 0.0392907134673766 HAUS5 essential 9.02323103655448e-10 1 1.77992336008321e-08 7.39342391632018 -2.06964087186916 0.16907740994365 20.836374128295 11.2091350849119 1.85887438865304 0.0639893962194401 17.021538474915 18.4936991283953 0.920396636537691 0.358078889565635 PCDHA11 other 1 1 1 1.85887438865304 0.920396636537691 0.042143202774924 -13.7467729781488 13.927758940095 -0.987005378056541 0.324388029469181 71.2421897389391 34.0719499904594 2.09093373754328 0.0373249718771733 TMEM132D-AS1 other 1 1 1 -0.987005378056541 2.09093373754328 0.00492339852182106 41.8000809397211 12.7155325065207 3.28732445285209 0.00112423325305158 24.8532198490994 32.7794533513115 0.758195067585072 0.448893981730795 ATP5L2 other 1 1 1 3.28732445285209 0.758195067585072 0.261133879341345 -48.5803836427746 40.5232986308517 -1.19882599107539 0.231488198075976 -116.372487476741 76.5685524194876 -1.51984703640711 0.129543040752624 TMEM150C other 1 1 1 -1.19882599107539 -1.51984703640711 0.402761245650956 -5.31857269445899 15.5299140650605 -0.342472770433729 0.732220672894799 -56.7672826169744 42.0473914372203 -1.35007858220484 0.177947910004976 APOBEC3B-AS1 other 1 1 1 -0.342472770433729 -1.35007858220484 0.0242247824784617 4.34299373604479 1.65196374883601 2.62898852296541 0.00897859110312872 2.32969720173437 3.16351643681607 0.736426457160786 0.462012413148892 UGDH-AS1 other 1 1 1 2.62898852296541 0.736426457160786 9.57899560074333e-07 -1.75676197224754 8.80720068577747 -0.199468824990498 0.842025547280534 -59.9882833300079 12.0291124480229 -4.986925144246 1.01848294237307e-06 NAIP other 0.00993533423709098 0.0152599299255757 1 -0.199468824990498 -4.986925144246 2.14736411473086e-09 29.7167679263977 4.75348999323339 6.25156841998186 1.297799365849e-09 -13.5276340322348 8.85180602518568 -1.52823435056588 0.127442197887831 ZNF286B other 2.56395275298865e-05 1 1.72204997854504e-05 6.25156841998186 -1.52823435056588 2.4399436063848e-09 27.9460606257611 5.63228228207284 4.96176491627764 1.15221738854153e-06 -35.392934276861 14.370432967177 -2.46289964663561 0.0143233871723393 ZNF324B other 2.90938875625324e-05 1 0.0136952558802046 4.96176491627764 -2.46289964663561 0.000958003741952074 11.1892743297114 4.214990504844 2.65463808681237 0.00833755821860614 -12.2266966362149 7.6983261550009 -1.58822793293479 0.113225428280741 MIR302B other 1 1 1 2.65463808681237 -1.58822793293479 0.197797705300318 25.2219535403164 13.9814461978259 1.8039588454189 0.0721780350547444 7.22580993688022 37.2566329167255 0.19394693967732 0.84634048592092 LINC01234 other 1 1 1 1.8039588454189 0.19394693967732 0.0825232064087001 17.1916921323872 9.56984862347259 1.79644347667318 0.0733670585583346 -25.7908875882667 26.6517111614131 -0.967701001713065 0.333924516833601 HOXC13-AS other 1 1 1 1.79644347667318 -0.967701001713065 0.55658753582415 1.24034328457705 8.35258661014143 0.14849810513441 0.882043213739083 12.8501357111468 12.1066538636712 1.06141101049453 0.289303559682815 MIR143 other 1 1 1 0.14849810513441 1.06141101049453 2.14320864452285e-26 194.254568075522 31.493942591734 6.1679977827389 2.08590939862694e-09 -295.619658221053 58.2477784724319 -5.07520914915179 6.57741623923903e-07 NOP14-AS1 other 3.21009790776633e-22 0.00987533274159348 2.75277463336797e-05 6.1679977827389 -5.07520914915179 0.0579353925214018 2.2552526672485 6.66512339166252 0.338366228908773 0.735314801556492 -29.4180998246167 14.1892551752831 -2.07326596507062 0.0389679783918113 SRD5A3-AS1 other 1 1 1 0.338366228908773 -2.07326596507062 0.0013890730381963 10.1381580686439 6.98670242029855 1.45106481695705 0.14777622955178 -42.3277740628949 15.0370831604926 -2.81489259659773 0.00519260085044399 ZNF564 other 1 1 1 1.45106481695705 -2.81489259659773 0.156235577842716 -16.2137214310713 9.7470528401657 -1.66344860307494 0.0972016589662667 5.32206476969873 14.3119059402488 0.37186275482231 0.710241155834239 ECSCR other 1 1 1 -1.66344860307494 0.37186275482231 6.92990093361266e-07 9.54516490140361 1.76205728553495 5.41705708421719 1.20263615951833e-07 9.71139492748898 10.3522450571641 0.938095541002324 0.348911753514189 LINC00964 other 0.00725144833693229 1 0.00149247147396225 5.41705708421719 0.938095541002324 0.267288244503993 49.4479454093657 40.3680465497601 1.22492787329734 0.221506116354539 82.6380436600131 56.1333713850356 1.47217317650803 0.1419599994512 VCAN-AS1 other 1 1 1 1.22492787329734 1.47217317650803 0.419199549087052 -7.20158044740533 7.0334592547221 -1.02390305916258 0.306656883542893 -17.4046116029167 16.2482002035637 -1.07117166116032 0.284902002748037 HS3ST5 other 1 1 1 -1.02390305916258 -1.07117166116032 0.00118265297467192 108.077644750287 31.7950514929765 3.3991970346128 0.000762193656976236 -157.889456265202 131.181975467167 -1.20359108561161 0.229645690697821 RNF103-CHMP3 other 1 1 1 3.3991970346128 -1.20359108561161 3.66031382491252e-09 6.12002314598775 0.963584232671051 6.35131100996025 7.373630407269e-10 -1.99645032634596 5.85627378598702 -0.34090795603223 0.733397995620176 BRD9P2 other 4.33344553731394e-05 1 9.85043286107066e-06 6.35131100996025 -0.34090795603223 1.81625611238853e-26 511.21127983385 43.5951375700474 11.7263371175845 1.27440097802177e-26 -278.63505472431 253.936928951308 -1.09726086660573 0.273360164023721 PDCD6 other 2.72093328196926e-22 1 1.9258747579865e-22 11.7263371175845 -1.09726086660573 0.0302304192211755 74.8040507233875 48.4436889127289 1.54414439532354 0.123541680382939 184.209503035681 69.4212582813112 2.65350279721553 0.00836377760258423 TMEM158 other 1 1 1 1.54414439532354 2.65350279721553 7.75256533544439e-09 159.29110875911 30.8386783202058 5.165302711911 4.22976068877543e-07 -126.666957670709 63.9213227945364 -1.98160726551072 0.0483786779813549 C15orf38-AP3S2 other 9.04569323339651e-05 1 0.00513112269155347 5.165302711911 -1.98160726551072 0.569039824990109 15.174116365516 15.8529031683855 0.95718217693885 0.339204724290159 -2.33121946791417 33.9469879483437 -0.0686723508860796 0.945293723195729 TMPRSS11BNL other 1 1 1 0.95718217693885 -0.0686723508860796 0.625642780148508 10.8371141487433 13.2020941653316 0.820863267071769 0.412342968187524 17.9867818701931 23.2828602250245 0.772533172314491 0.440376119824554 SLC7A11-AS1 other 1 1 1 0.820863267071769 0.772533172314491 0.292048724238763 -3.33064229366134 2.97045147214915 -1.12125793836032 0.263021428625631 -20.5638496354146 16.8865153701988 -1.21776750173725 0.224212324913693 LINC01018 other 1 1 1 -1.12125793836032 -1.21776750173725 0.0253542692397448 24.8384147589991 11.9552633297695 2.07761335521147 0.0385471130044833 -28.7285003480896 27.193725485384 -1.05643856570997 0.291569798465153 YJEFN3 other 1 1 1 2.07761335521147 -1.05643856570997 0.363156462245046 17.0121455521485 12.1764504553782 1.39713503656022 0.163391899146156 14.2952274127105 20.2992358788349 0.704224902751908 0.481831822073883 PCDHA10 other 1 1 1 1.39713503656022 0.704224902751908 0.0236705848821324 4.90708033355777 2.10841953934003 2.32737377073149 0.0205688225019948 11.1167660588828 5.87187851976489 1.89322139779689 0.0592304540705196 HOXC-AS2 other 1 1 1 2.32737377073149 1.89322139779689 0.402063415040263 -6.65806459263672 12.8568765788376 -0.517860193477776 0.60491589493136 -41.6959599108225 31.443369596769 -1.32606525463184 0.185769754682221 FZD10-AS1 other 1 1 1 -0.517860193477776 -1.32606525463184 0.0113962995655951 -5.94131609514673 2.36257492062789 -2.51476304233676 0.0124011607711605 -13.1940589567956 4.85756635354868 -2.71618707733281 0.00696278548567371 PTTG2 other 1 1 1 -2.51476304233676 -2.71618707733281 0.000386682000566181 -10.5960699125097 6.99940420024015 -1.51385312369104 0.131056335117406 -50.329493592682 13.1026780895727 -3.84116081068457 0.000147811213633755 KIAA1456 other 1 1 1 -1.51385312369104 -3.84116081068457 0.0164707587060784 4.61291397323868 8.04049147660602 0.573710448753046 0.566571846745156 -30.6007863645956 14.8779754435054 -2.05678430380483 0.0405276004220882 ZNF718 other 1 1 1 0.573710448753046 -2.05678430380483 0.00116618017891512 41.6027379350399 14.2661282020819 2.9161898271017 0.00379848759683566 -8.35726311740717 26.6517273304198 -0.313573038392463 0.754053540389304 SMIM20 other 1 1 1 2.9161898271017 -0.313573038392463 0.063577672905723 5.21018830797171 5.50520301601534 0.946411656902499 0.34465275432112 -14.5665922453633 8.55339538619756 -1.70301869464249 0.0895355484912018 AACSP1 other 1 1 1 0.946411656902499 -1.70301869464249 0.184891715431053 91.6968034520381 50.2881451412995 1.82342783163683 0.0691772527331655 17.1281128543501 152.541605490157 0.112284860247229 0.910668389939975 CHCHD10 other 1 1 1 1.82342783163683 0.112284860247229 0.896522571820729 4.99568927033092 10.6972200160358 0.467008181830613 0.640813836013136 1.40071704191887 26.3358338983805 0.0531867358870685 0.957616520088206 CDK3 other 1 1 1 0.467008181830613 0.0531867358870685 0.217298441718287 5.83725074246923 3.33284001805377 1.75143442554975 0.0808321432879089 4.56084853627492 18.7162919478436 0.243683340107355 0.807632714232471 GPR162 other 1 1 1 1.75143442554975 0.243683340107355 5.80872128978267e-12 52.1343977695504 7.063207727805 7.38112197441374 1.36541339875351e-12 -4.61675747955574 25.7120025505151 -0.179556511418565 0.85761439004733 ATP6V1E2 other 7.51706622110776e-08 1 1.91335379567329e-08 7.38112197441374 -0.179556511418565 0.000335344442049541 41.9877176064059 10.3790196919763 4.0454415592703 6.55193562316559e-05 11.0120132822034 51.1537216997281 0.215272963848922 0.829691644044929 GLI4 other 1 1 0.691949921162518 4.0454415592703 0.215272963848922 0.0149127507375688 22.2664314193478 8.36790043358557 2.6609340773199 0.00818788733189697 33.4901073628726 14.6970031053823 2.27870315619705 0.0233474082408312 CCDC169-SOHLH2 other 1 1 1 2.6609340773199 2.27870315619705 0.0919993105553447 352.324086199531 215.352485780138 1.63603445264724 0.102843949614388 -1982.44728778773 1517.58543314025 -1.3063167611497 0.192410133229078 SELENOP other 1 1 1 1.63603445264724 -1.3063167611497 4.74271358712794e-09 14.1623123699763 2.30761465439347 6.13720854260162 2.49720202307742e-09 -3.37493151856776 7.39541572130626 -0.456354537155301 0.64844657421733 NT5C1B-RDH14 other 5.5902365051477e-05 1 3.28906478459528e-05 6.13720854260162 -0.456354537155301 0.17802489143531 3.04521676076035 7.01231801441616 0.434266779472906 0.664387387481223 36.35157101617 19.5290732011994 1.86140789384401 0.0636033475366251 LINC02381 other 1 1 1 0.434266779472906 1.86140789384401 4.37106111867392e-05 40.1330364081926 9.29011796525984 4.31997059222166 2.08864106401491e-05 -54.8825384678282 54.7797835559938 -1.00187578163264 0.317165330580796 SNHG18 other 0.392696130901665 1 0.229249243186277 4.31997059222166 -1.00187578163264 0.0114074926942207 7.90198642057359 6.6115110828167 1.19518614150263 0.232913350339408 -24.2359030596221 11.4430621850466 -2.1179560739688 0.0349617456911549 SMAD1-AS1 other 1 1 1 1.19518614150263 -2.1179560739688 0.000208576323721286 3.15573002837819 1.9270517150844 1.63759488324888 0.102492238392828 -13.4383647830994 4.5442789436388 -2.95720508132777 0.00333614784597102 GLUD1P3 other 1 1 1 1.63759488324888 -2.95720508132777 0.0309878414477785 5.34123027317995 3.4642242852151 1.54182576918466 0.124119895384705 -10.2349875538941 6.83308779898711 -1.49785687744437 0.135171824258781 SNHG21 other 1 1 1 1.54182576918466 -1.49785687744437 6.13807023367162e-05 108.995171417133 36.6726330967678 2.97211195960564 0.00318399734888351 -123.988262003105 68.8246986750241 -1.80150824326238 0.0725729056943712 THAP9-AS1 other 0.541930220930868 1 1 2.97211195960564 -1.80150824326238 0.000187894337512696 63.5207143964115 27.4836500077418 2.3112182835438 0.0214559088101235 -94.0416982551963 40.6160431303142 -2.31538306066568 0.0212240792331845 TMED7-TICAM2 other 1 1 1 2.3112182835438 -2.31538306066568 0.182476436210596 4.42018840675278 3.49880644280987 1.26334179355259 0.207391806455444 -8.45029967491629 9.33039809541329 -0.905674076122256 0.365794070127333 ZNF345 other 1 1 1 1.26334179355259 -0.905674076122256 5.42734721948236e-06 105.249510948167 22.9589697993146 4.584243625396 6.57909789552631e-06 -54.4071839455209 66.064472228539 -0.823546788617463 0.410820190303813 SHANK3 other 0.0530251823343426 1 0.0747911848763431 4.584243625396 -0.823546788617463 0.000326287887128647 31.0852435609835 8.65996312635288 3.5895353256631 0.000383183010809712 -16.7472807784155 22.5042668122166 -0.744182466292307 0.457312202611792 ZNF550 other 1 1 1 3.5895353256631 -0.744182466292307 0.00480745690335829 -5.14552669715438 3.92084336897817 -1.31235201535107 0.190341915888889 -19.1658545205706 5.82092130989548 -3.2925809335352 0.00110375118078609 DCANP1 other 1 1 1 -1.31235201535107 -3.2925809335352 8.63723197641256e-12 395.434358638388 65.026415884114 6.08113415543471 3.43022134686032e-09 -136.830028750413 135.701164435311 -1.00831875186775 0.31407049071366 LINC00958 other 1.11290734016076e-07 1 4.49873529640731e-05 6.08113415543471 -1.00831875186775 1.56300329015026e-08 33.0392192733207 5.38061240407354 6.1404198615584 2.43698361620865e-09 12.44602006195 21.589660110077 0.576480592954813 0.564695645409815 RPL32P3 other 0.000179714118301477 1 3.2107259143549e-05 6.1404198615584 0.576480592954813 0.159972712952058 45.5204795235846 28.0419650543917 1.62329848979166 0.105510269116587 -11.4711210433401 38.5730139982344 -0.297387210754782 0.766363867803904 FOXD1 other 1 1 1 1.62329848979166 -0.297387210754782 0.00252088839036434 669.547610192094 199.787950452358 3.35129124992829 0.000901617957035662 -321.184230637129 907.495405472953 -0.353923809090515 0.723631268266565 MALAT1 other 1 1 1 3.35129124992829 -0.353923809090515 9.96835333143781e-07 18.8952572047133 4.90188521644863 3.85469189309225 0.000140381055966198 -9.40844861381272 9.07035696628702 -1.03727434860418 0.300401088006403 ABCA11P other 0.010323226710037 1 1 3.85469189309225 -1.03727434860418 0.795780807762638 -1.95557998643306 10.0673704532259 -0.194249332089139 0.846103912608485 -30.8679219270433 45.8378614732079 -0.67341540235435 0.501169124225143 PRB1 other 1 1 1 -0.194249332089139 -0.67341540235435 0.207747107927149 18.4011245503332 10.5597088325425 1.74257878149303 0.0823956720274562 15.447720582145 17.4222254039357 0.886667473528114 0.375943079190923 PCDHA12 other 1 1 1 1.74257878149303 0.886667473528114 6.51943987528495e-05 16.6465530327862 4.12502202849826 4.03550645736707 6.82135992261229e-05 5.4981398498868 7.61946297481031 0.72159151741579 0.471072561030548 FAM86EP other 0.573515125828817 1 0.719380617438692 4.03550645736707 0.72159151741579 0.000930724810301108 555.306168116622 148.640533974958 3.73589998142887 0.000221658299444111 401.497085743514 224.999799571797 1.78443308175214 0.0753065908704708 PCDHGA12 other 1 1 1 3.73589998142887 1.78443308175214 0.0314603531739994 19.5203539317529 7.81402867651131 2.49811649532723 0.0129917779082778 -12.6749059479332 32.0760497439281 -0.395151711296138 0.692996691038978 HOXA10-AS other 1 1 1 2.49811649532723 -0.395151711296138 0.722108352450649 2.96877882094813 4.60255888794156 0.645027884102941 0.519371284953254 -9.83468837423307 23.2882874377507 -0.422301914665089 0.67308825694226 C8orf88 other 1 1 1 0.645027884102941 -0.422301914665089 0.000283325988427457 117.760533048847 32.4080094738374 3.6336860844204 0.000326133158053211 -89.2462316206938 107.764453498593 -0.828160202397898 0.408206787707963 CCDC71L other 1 1 1 3.6336860844204 -0.828160202397898 0.04185618838131 36.396285689806 15.1843441491133 2.39696132624414 0.0171103668989691 -22.5867044519278 62.3306873341723 -0.362368929622645 0.717317816747539 HOXA10 other 1 1 1 2.39696132624414 -0.362368929622645 0.000312206450691432 48.0826019845646 18.5178791278225 2.5965501585072 0.00985244192308415 -92.3848066238622 37.5483825337563 -2.4604204066795 0.0144070578869117 TMEM200B other 1 1 1 2.5965501585072 -2.4604204066795 0.0010083297475811 559.100905746408 150.668935612752 3.71079083735884 0.00024382470452494 408.764142549476 228.070226929327 1.79227314346533 0.0740397128479171 PCDHGB6 other 1 1 1 3.71079083735884 1.79227314346533 4.45276982242318e-06 4.26746781461355 1.43750689662746 2.96865901974138 0.00321899785002089 -7.08372778633966 2.65313016023882 -2.66995109870599 0.00797723927723726 SERPINE3 other 0.0438063495129992 1 1 2.96865901974138 -2.66995109870599 0.0578641695521611 -4.0858041114428 7.7125238297777 -0.529762267400419 0.596644121716454 -57.8357365527637 24.139159785592 -2.39592997711893 0.0171522401613682 C1orf210 other 1 1 1 -0.529762267400419 -2.39592997711893 0.000137791499667173 4.24496852496044 1.00008683137915 4.24459996049192 2.87709886157093e-05 4.15511018640398 5.47800855211594 0.758507429638645 0.44870906136019 RAD21-AS1 other 1 1 0.312711875264145 4.24459996049192 0.758507429638645 0.178918680865808 47.7449749604032 43.213263214255 1.10486853824669 0.27004659770346 -98.6355888660398 84.9500626956306 -1.16110083661084 0.246466289689029 TRNP1 other 1 1 1 1.10486853824669 -1.16110083661084 0.14788265321362 4.37737698990589 9.39862955335292 0.465746305358347 0.641714931294012 -22.1167532522268 13.4908031733757 -1.63939485055082 0.102116819342046 LINC02159 other 1 1 1 0.465746305358347 -1.63939485055082 0.000367488230088981 578.371558245234 144.99607077249 3.98887745829157 8.24358160865337e-05 414.428806181659 223.610675515467 1.85334982431549 0.0647583203007152 PCDHGA5 other 1 1 0.861948893000796 3.98887745829157 1.85334982431549 0.724416921078262 -26.9703132786986 36.3194023907921 -0.742586923333747 0.458288735154936 18.4963852071787 83.3771503471712 0.221839978101461 0.824583124654802 NACA2 other 1 1 1 -0.742586923333747 0.221839978101461 0.000439685578475095 573.492201974096 145.261710409781 3.94799290436745 9.7068200566923e-05 401.684829868421 224.020340814822 1.79307302367001 0.0739114497612071 PCDHGA7 other 1 1 1 3.94799290436745 1.79307302367001 0.440224980927049 6.7135000856604 5.56169649774293 1.20709572850387 0.228292388946026 -8.33031009080006 27.3707744310972 -0.304350544109399 0.761059909782323 CA3-AS1 other 1 1 1 1.20709572850387 -0.304350544109399 0.000882886426493998 -0.775023706934655 1.86012356755319 -0.416651732419112 0.677212502123722 -9.95488512510591 2.69615548178583 -3.69225187210352 0.000261255770243391 GRPEL2-AS1 other 1 1 1 -0.416651732419112 -3.69225187210352 0.683748720203835 54.362945752875 114.180492836913 0.476114127747923 0.634318986293857 228.539694781593 266.788054519312 0.856633911864485 0.39229027879917 EIF5AL1 other 1 1 1 0.476114127747923 0.856633911864485 2.71451602762978e-11 58.6783410805783 9.9852356715435 5.87651038100215 1.06317980464422e-08 -31.4912406019671 18.4595408909222 -1.70596012046288 0.0889980750653151 ALG11 other 3.45585035477547e-07 1 0.000137320303567848 5.87651038100215 -1.70596012046288 0.0161928929394342 11.7455193248968 4.16745103145217 2.81839408219851 0.00512687384681013 -7.09051283844551 20.5395727714971 -0.345212284468013 0.730161586778226 MINCR other 1 1 1 2.81839408219851 -0.345212284468013 0.00038187404503997 298.945036175253 91.0778889615111 3.28230089194958 0.00114452523588813 -347.479793422387 214.292471855748 -1.6215212341024 0.105900066104112 ATXN7L3B other 1 1 1 3.28230089194958 -1.6215212341024 1.51340973692914e-05 1190.16083478316 279.515388975477 4.25794386185862 2.80423278634089e-05 -1920.12355486024 1408.62515589447 -1.36311888711157 0.173920971718524 PRKDC ts 0.142169710687124 1 0.304960315514572 4.25794386185862 -1.36311888711157 0.000361744477466575 579.677286093834 145.15623649241 3.99347144911783 8.09292556643888e-05 414.550184085839 223.857680586948 1.85184704406345 0.064974532727649 PCDHGA6 other 1 1 0.8467628020165 3.99347144911783 1.85184704406345 4.28144557872721e-08 56.2780354930728 9.49415299251311 5.92765205463325 7.95165854786543e-09 -11.8956632651306 48.0390515908232 -0.247624856678124 0.804583486286979 OTUD6B-AS1 other 0.000481491369783662 1 0.000103069398097432 5.92765205463325 -0.247624856678124 0.000389565443999448 576.993622529428 145.592797064279 3.96306434221939 9.14085890082084e-05 429.057611082205 224.530937481835 1.91090642516431 0.0569155743572734 PCDHGA8 other 1 1 0.951472002986441 3.96306434221939 1.91090642516431 2.6133681963261e-09 111.300736715627 21.4945042333979 5.17810206307009 3.99798778779894e-07 -65.7771027088316 39.7365363100315 -1.65533055512506 0.0988502064764902 UTP14C other 3.11199884818512e-05 1 0.0048539569731667 5.17810206307009 -1.65533055512506 0.00217888970174788 3.25872865638645 0.982667932305552 3.31620535203664 0.00101739534501101 -4.67117673852983 3.4495262137226 -1.35415023661724 0.176643933890703 ETV3L other 1 1 1 3.31620535203664 -1.35415023661724 0.00131530121021088 563.526497387627 153.802872790808 3.66395300141173 0.000290863490262856 364.178986908908 232.814122945283 1.56424783128169 0.118753943400983 PCDHGA10 other 1 1 1 3.66395300141173 1.56424783128169 0.000991653697743398 551.557511719044 148.627145065665 3.71101464322254 0.000243618209590244 409.188829571861 224.979532543505 1.81878246854626 0.0698851061136861 PCDHGA11 other 1 1 1 3.71101464322254 1.81878246854626 0.000513614498187861 585.811615540473 149.568850187871 3.91666857640909 0.000109912027578519 392.359970593569 230.66274450333 1.70101145479046 0.0899183866523301 PCDHGB2 other 1 1 1 3.91666857640909 1.70101145479046 0.000647327605041396 566.723037041857 149.18669976712 3.79875041090466 0.000174214646109269 459.615258134073 230.073398093613 1.99768970225346 0.0466018375766409 PCDHGB4 other 1 1 1 3.79875041090466 1.99768970225346 0.000513575673977988 -17.188531219727 12.2180977866764 -1.40680910562614 0.160460541459677 -85.7183571053282 23.0741332767347 -3.71491124183445 0.000240049316128537 CLDN23 other 1 1 1 -1.40680910562614 -3.71491124183445 7.42423730662376e-05 59.4691009860442 18.0082624760603 3.30232309003164 0.00106840600658099 -94.6585509827053 50.5429187856535 -1.87283507278519 0.0620113894443633 ZNF260 other 0.649175310091181 1 1 3.30232309003164 -1.87283507278519 0.0862236393467715 -125.469866254734 60.5966196541042 -2.07057533854094 0.0392287045592119 -314.320214292302 283.299274453003 -1.10949883263625 0.268077763842995 LYN other 1 1 1 -2.07057533854094 -1.10949883263625 5.87823786663147e-21 90.8314666929156 14.9156378472991 6.08968034909503 3.25007139350031e-09 -73.5132131072477 28.7586646904099 -2.5562109332483 0.0110448944442553 PINX1 other 8.58751769936191e-17 1 4.26604371110851e-05 6.08968034909503 -2.5562109332483 1.88039566093296e-05 3.6958231796249 2.10788005305049 1.75333656878453 0.080504708989321 -9.85024516200777 4.03160596672177 -2.44325592414413 0.0150972452664682 RBPMS-AS1 other 0.175046032076249 1 1 1.75333656878453 -2.44325592414413 0.000441607305647829 621.631563355612 157.346048593686 3.9507287848127 9.60167259852827e-05 422.754834457315 238.177490690109 1.7749571264371 0.0768614890663431 PCDHGB7 other 1 1 0.996845649179205 3.9507287848127 1.7749571264371 0.0929221690757606 12.3171710494099 13.8316875876153 0.89050385004636 0.373868622879556 -83.9345624602122 50.0960447232779 -1.67547284269352 0.094824442104027 NPIPB11 other 1 1 1 0.89050385004636 -1.67547284269352 0.000507002863817189 558.777124791103 143.224463686011 3.90140839358352 0.000116737655447295 407.639259140863 226.474176948547 1.79993703756113 0.0728182718378177 PCDHGB1 other 1 1 1 3.90140839358352 1.79993703756113 0.000550446950760984 546.785783999298 140.952304741378 3.87922556500619 0.000127379458944343 399.6033813232 222.881317784416 1.79289760710102 0.0739395626771094 PCDHGA3 other 1 1 1 3.87922556500619 1.79289760710102 0.486236710015156 12.3861955756245 11.9343078971895 1.03786459024921 0.300124104050467 38.6323180330585 49.0624748687689 0.78741070719305 0.431629811718559 HOXA-AS3 other 1 1 1 1.03786459024921 0.78741070719305 0.118168126974008 -0.263366670179966 1.59765097585348 -0.16484618615732 0.869169132735597 16.0544684606769 7.87413414922869 2.0388868358624 0.0422828057347815 RHPN1-AS1 other 1 1 1 -0.16484618615732 2.0388868358624 3.55829861238227e-05 27.3758680386703 6.1865860784731 4.42503631104845 1.3252000663223e-05 -22.0613558890071 30.4839400501451 -0.723704214504977 0.469777701943237 LRRC24 other 0.322417437267958 1 0.147463964268016 4.42503631104845 -0.723704214504977 0.195882479670204 98.0505477940486 54.2019639490795 1.80898514832715 0.0714035766979114 81.9577595300015 155.977502767646 0.525446029560372 0.599641658092882 CHKB-CPT1B other 1 1 1 1.80898514832715 0.525446029560372 0.021698488870899 -5.84463032919592 4.84099297408487 -1.2073205560272 0.228200345267139 -31.8755801403131 11.7483389136843 -2.71319889343547 0.00702443572000753 SIGLEC14 other 1 1 1 -1.2073205560272 -2.71319889343547 0.757434454524376 -0.327485029537527 1.8964852170261 -0.1726799801008 0.863013527316559 -2.88852384068558 3.97268002665117 -0.727097028028332 0.467704827808812 SPON1-AS1 other 1 1 1 -0.1726799801008 -0.727097028028332 1.99515128876064e-06 10.9145902560879 4.76386736545585 2.29111967625981 0.0226060921186774 -31.760445251614 10.1079252704435 -3.1421329701046 0.00183406468416653 NAV2-AS2 other 0.0201590086216375 1 1 2.29111967625981 -3.1421329701046 0.000705293523075113 102.679619825902 29.8839594846675 3.43594428571566 0.000669172166558007 -180.659911174276 150.534394533983 -1.20012381046573 0.230987375227885 AP5B1 other 1 1 1 3.43594428571566 -1.20012381046573 2.61127844565981e-05 273.104501630754 61.8774820786655 4.4136330771112 1.39141614251589e-05 -68.7209205345495 168.475441244487 -0.407898741958619 0.683620787695095 CHMP4A other 0.23987203801831 1 0.154558505110665 4.4136330771112 -0.407898741958619 0.391679726378539 1.44740061162079 5.82094109672866 0.2486540556877 0.8037878965533 -17.8103975535169 14.1265209776284 -1.26077734084156 0.208307546565353 SIGLEC12 other 1 1 1 0.2486540556877 -1.26077734084156 0.595010282748273 5.54261329198204 7.40923232473925 0.748068497390125 0.454975204978405 -4.91567817812878 12.8094485778961 -0.383754081858859 0.701418794413754 PABPC4L other 1 1 1 0.748068497390125 -0.383754081858859 4.66518372462443e-05 20.6580691069001 7.45249100498 2.77196833825035 0.00590227899942048 -31.0118043893088 15.8320488859649 -1.95879918086917 0.0510155248087036 BBOX1-AS1 other 0.417907158051856 1 1 2.77196833825035 -1.95879918086917 0.413574685743648 46.092836365024 37.8792075534218 1.21683739819579 0.224568411916482 7.29271920541754 78.4598335916381 0.0929484408974679 0.926003052558403 CSNK2A3 other 1 1 1 1.21683739819579 0.0929484408974679 0.00174408217287634 16.1223397482985 5.69115554771132 2.83287631363055 0.00490761776351013 -27.9058958914839 20.6124076356782 -1.35383970590516 0.176748907949124 SMG1P6 other 1 1 1 2.83287631363055 -1.35383970590516 4.03727761003095e-05 23.7130556516021 12.8872743768189 1.84003653202699 0.0666888538239964 -93.5503175152009 27.1793615992513 -3.44196154768322 0.000654235891644373 FPGT other 0.364122067648692 1 1 1.84003653202699 -3.44196154768322 0.0438437440936824 -2576.33632522834 1064.81313557441 -2.41951966890279 0.0160980827537267 -3912.71663613243 3419.83465256807 -1.14412450707061 0.253427107629266 IGLL5 other 1 1 1 -2.41951966890279 -1.14412450707061 3.14939521321205e-09 242.339495467792 37.6063215967297 6.4441159139815 4.27212870372747e-10 -63.9354137986518 130.94798809778 -0.488250447581605 0.625706847637602 MEX3A other 3.73644248095478e-05 1 5.73533278475413e-06 6.4441159139815 -0.488250447581605 0.000321437321397135 1513.08748837522 542.592441307544 2.78862618271823 0.00561723234039343 -4188.14008747063 2017.93897878251 -2.07545427860137 0.0387608370506473 EEF1G essential 1 1 1 2.78862618271823 -2.07545427860137 0.790919133839908 4.18789124315252 14.0282621259715 0.298532434420312 0.765490584504421 -16.3135577978146 37.1934716037674 -0.438613474203418 0.661237605332742 CKLF-CMTM1 other 1 1 1 0.298532434420312 -0.438613474203418 1.55732681559946e-08 186.862569680799 32.8802012904306 5.68313338565792 2.97708171998968e-08 -136.4305553065 149.794125944592 -0.910787084915232 0.363093118725669 SYS1-DBNDD2 other 0.000179077010525782 1 0.000378387086610688 5.68313338565792 -0.910787084915232 0.0801076993515566 -1.93336839836452 4.43894970520812 -0.435546362711914 0.663459530432512 -17.0658000135113 8.22486740682333 -2.0749027515451 0.0387943920971198 SLC22A18AS other 1 1 1 -0.435546362711914 -2.0749027515451 0.00614033706935294 -24.7699755356681 7.82432447473195 -3.16576537893602 0.00169558338368652 -31.6087850430063 15.6090406974643 -2.02503059961533 0.0436941662534208 GVINP1 other 1 1 1 -3.16576537893602 -2.02503059961533 0.0434433156991121 8.18313419458068 4.0155876781909 2.03784224137956 0.0423878380146973 -10.669487696114 12.5668370738326 -0.849019338233534 0.396505218623115 NPIPA2 other 1 1 1 2.03784224137956 -0.849019338233534 9.9243950166912e-09 60.916514192596 13.653400834566 4.46163669628557 1.13011933690459e-05 -92.5883727204833 31.9974088095362 -2.89362095760983 0.00407127123373999 MPV17L2 other 0.000115220342031961 1 0.126279534705719 4.46163669628557 -2.89362095760983 0.0017126060920623 2.32113932503466 1.66692949274128 1.392464009511 0.16475176405422 -7.51477021728338 3.35589331440483 -2.2392756602324 0.0258268888068258 TMEM9B-AS1 other 1 1 1 1.392464009511 -2.2392756602324 0.00027485315317284 423.050850172226 113.43808797136 3.72935455575587 0.000227013009744166 -46.1995854647323 265.06247468961 -0.174296967229452 0.861742298980869 ATP6V1G2-DDX39B other 1 1 1 3.72935455575587 -0.174296967229452 2.26077090726583e-05 39.2780974237039 11.6133479804736 3.38215108078612 0.000808735226291619 -57.6688035327187 27.3598764511774 -2.10778742497709 0.0358292632876098 BORCS8 other 0.209008270376726 1 1 3.38215108078612 -2.10778742497709 3.81989003408541e-06 29.0375273945467 6.09172490425928 4.76671679219197 2.85403541499283e-06 -20.3754369336162 24.7291012886184 -0.823945710594585 0.410587938533731 INMT-MINDY4 other 0.0378054516673433 1 0.0331542680305479 4.76671679219197 -0.823945710594585 1.14515259183992e-22 518.370982445352 47.896680354155 10.8226912306332 2.12277845537809e-23 -0.633503954399083 282.540829208831 -0.00224216781756116 0.998212438751887 DPP3 other 1.69001619503735e-18 1 3.18629046152251e-19 10.8226912306332 -0.00224216781756116 8.54555940948364e-11 144.1474894536 22.7561634929499 6.33443723931138 8.0692971660005e-10 -171.167488721529 106.452832409129 -1.60791859500443 0.108839165875842 STX16-NPEPL1 other 1.07135678316696e-06 1 1.07684770680277e-05 6.33443723931138 -1.60791859500443 1.41557293217904e-08 303.000860903979 108.107827864652 2.80276522883548 0.00537562657255829 -676.666684254445 158.738142613497 -4.26278569922557 2.65979596703592e-05 ANKHD1-EIF4EBP3 other 0.000163088157516348 0.387106705042407 1 2.80276522883548 -4.26278569922557 2.3066982310619e-26 530.351240041484 84.2800738391607 6.29272396051291 1.02557102148172e-09 -945.9314343085 147.245935886368 -6.42415988335659 4.79904258562534e-10 BRK1 other 3.4545112708383e-22 7.33341697509408e-06 1.36462480118357e-05 6.29272396051291 -6.42415988335659 0.0840043343994409 181.27100957034 167.325350050261 1.08334457101623 0.279473661168501 -440.989945567305 350.082062992398 -1.25967592226192 0.208707123507275 SAA2-SAA4 other 1 1 1 1.08334457101623 -1.25967592226192 3.11373751372626e-10 74.1343564099107 12.6237478479493 5.87261067813184 1.07425554917134e-08 -19.2179576651328 23.3037904647667 -0.824670891810013 0.410172747163547 PIGY other 3.8389269806731e-06 1 0.000138697133953511 5.87261067813184 -0.824670891810013 1.88703720815178e-47 1020.37965880556 58.1592243454273 17.5445885031956 1.99805133384754e-48 491.895183227697 248.648511740127 1.97827519571803 0.048777038861913 CHMP1B other 2.88980878056364e-43 1 3.06201366912136e-44 17.5445885031956 1.97827519571803 0.878844434599923 1.05242242432741 3.20166340589265 0.328711138838152 0.742589042898647 -2.71760001201947 8.12471017280783 -0.334485779088449 0.738232141938858 EID3 other 1 1 1 0.328711138838152 -0.334485779088449 0.000443247645640801 38.4750137713768 9.72813244965608 3.95502569177469 9.42671943112741e-05 25.0197500290809 22.731014841022 1.10068776973074 0.271859843941281 MSH5-SAPCD1 other 1 1 0.979341881699826 3.95502569177469 1.10068776973074 0.0126332653500776 3.88878091801455 1.34735879530143 2.88622520710569 0.00416394502591456 2.72766257032619 2.50792819106143 1.08761589747582 0.277583211260466 TOLLIP-AS1 other 1 1 1 2.88622520710569 1.08761589747582 3.91622057089132e-14 52.5725858241275 11.9757255067771 4.38992909401408 1.54239179116217e-05 -60.8513223313934 17.2857761671107 -3.52031182997579 0.00049358917676399 HTD2 other 5.29942967653014e-10 1 0.170819890871211 4.38992909401408 -3.52031182997579 0.331039441634853 9.5584306832597 7.44102799030457 1.28455781858556 0.199875968249371 -3.7512125558604 20.2971462189499 -0.184814777180754 0.853491391307355 PDXDC2P other 1 1 1 1.28455781858556 -0.184814777180754 0.0056111394463773 29.9883166880544 9.44062735585691 3.17651736030549 0.00163630138791222 6.75846119511238 26.8195499073038 0.251997562169075 0.801205224686519 SNHG9 other 1 1 1 3.17651736030549 0.251997562169075 0.0239237934275092 3.87927972920482 1.78340390415591 2.17521096604355 0.0303553703928432 -9.02800940989719 7.69918165611506 -1.17259337591116 0.241842104893527 PGAM1P8 other 1 1 1 2.17521096604355 -1.17259337591116 2.20715066900029e-06 -2.23294731462859 2.65136226280649 -0.842188691433282 0.400317270574446 -24.3240224522766 5.32766467709239 -4.56560687027915 7.13604930120915e-06 CARD17 other 0.0222238000861639 0.105449400523968 1 -0.842188691433282 -4.56560687027915 0.99762166657623 6.14807231665987 90.9096489376531 0.0676283803590121 0.946123698274079 5.50933301307972 167.965615693634 0.0328003620879682 0.973854238444294 FXYD6-FXYD2 other 1 1 1 0.0676283803590121 0.0328003620879682 0.233825875649224 30.0653798969642 17.8118258021192 1.68794486488787 0.0923961213749893 42.1178954562985 33.4097199471333 1.26064796481218 0.208354115892394 MIR100HG other 1 1 1 1.68794486488787 1.26064796481218 0.0017677562696189 12.1072677062963 18.9770085313418 0.637996641372657 0.523943833273841 -821.345386558659 247.155653569293 -3.3231907694492 0.000995825425749538 WTAPP1 other 1 1 1 0.637996641372657 -3.3231907694492 0.0277209644996373 51.6989476373189 103.228321312386 0.500821353869247 0.61684440892574 -481.813613266241 209.971241617401 -2.29466478149506 0.0224055386633686 EID1 other 1 1 1 0.500821353869247 -2.29466478149506 0.173736354413172 5.23153175203594 8.1680879308689 0.640484259757402 0.52232051286657 -30.1082432171837 19.2281352523894 -1.56584311593306 0.118383024323991 SOGA3 other 1 1 1 0.640484259757402 -1.56584311593306 0.107024138137189 10.0248115180406 6.13735728970952 1.63340849242217 0.103366578921667 -7.85566892262448 11.9446736984557 -0.657671286879952 0.511222172399479 NOX5 other 1 1 1 1.63340849242217 -0.657671286879952 0.309934627167145 -29.2498451110849 62.9760613910924 -0.464459740177116 0.642634235955166 -244.936277500721 161.632715529703 -1.51538799987376 0.130661311657929 HCAR3 other 1 1 1 -0.464459740177116 -1.51538799987376 0.122819648546337 22.4140100918125 11.4567517629956 1.9564018279778 0.0513331806617861 23.0348849908172 19.0994335577972 1.2060506884202 0.228735740520029 PCDHA3 other 1 1 1 1.9564018279778 1.2060506884202 3.09996261928759e-05 44.1236338234809 15.6970488581406 2.81095091327298 0.00524693065107162 -36.6636465167651 31.5417526715445 -1.16238456684879 0.2459536390291 CARD18 other 0.2828405893838 1 1 2.81095091327298 -1.16238456684879 2.55465571662585e-13 269.320050140545 40.9249942210025 6.58082072501141 1.91242718131978e-10 -307.979351364759 111.427553735072 -2.76394249933014 0.00604160120826177 NEDD8-MDP1 other 3.40816619155054e-09 1 2.58426285011742e-06 6.58082072501141 -2.76394249933014 7.97001783510001e-05 91.079925320329 27.3237500910841 3.33336108757813 0.000958995507480117 -80.4486385816374 54.0515407117325 -1.4883690182059 0.137641473263995 POLR2M other 0.693710352367105 1 1 3.33336108757813 -1.4883690182059 8.97922128061253e-11 4.60774824588755 4.20313720426404 1.09626405752661 0.273795352777143 -35.6941522768966 7.72297243912214 -4.62181531246717 5.54305710278003e-06 FDXACB1 other 1.12446788097111e-06 0.0821203909776861 1 1.09626405752661 -4.62181531246717 0.168823135544351 7.70883853476799 4.18168479622912 1.84347671104229 0.0661839704036931 10.2054832988137 9.70719588988004 1.05133175580119 0.293899516726218 RAB44 other 1 1 1 1.84347671104229 1.05133175580119 0.00351387713100443 35.7139900446166 11.7276874858698 3.04527129390572 0.00251905526391153 -41.3756038889848 47.5701196114964 -0.869781371728682 0.3850759361444 TRIL other 1 1 1 3.04527129390572 -0.869781371728682 0.220528089667156 -36.2841420556947 52.3371451641836 -0.693277058614296 0.488649812224977 -348.362888987994 201.38802344438 -1.72980936517412 0.0846501374078797 SNHG1 other 1 1 1 -0.693277058614296 -1.72980936517412 6.88963496392024e-07 100.370219469126 18.6674522107981 5.37674977472647 1.46553068158076e-07 9.29453093965663 61.1629292314607 0.151963469644874 0.879311510742399 AGAP2-AS1 other 0.00721000298974253 1 0.00181300800618356 5.37674977472647 0.151963469644874 0.0945249560934157 -12.8578317492253 5.92607610300251 -2.16970412221178 0.0307671551422622 -18.7719634294324 31.0406003227954 -0.604755166917528 0.54577160170133 KLRC4 other 1 1 1 -2.16970412221178 -0.604755166917528 0.00194177129738159 -10.2598695624617 6.95860193185081 -1.47441535856511 0.141352893795349 -36.8164474624195 10.3308065281747 -3.56375345545498 0.000421271312608547 TIFAB other 1 1 1 -1.47441535856511 -3.56375345545498 4.57695489535245e-08 6.91373507301036 1.15887006279319 5.96592775582311 6.47955186230186e-09 4.21966239830377 3.89328103183011 1.08383195659529 0.27926037084922 TMEM5-AS1 other 0.000513763187003312 1 8.42730515210979e-05 5.96592775582311 1.08383195659529 0.00901809264239639 225.711478375267 76.4619027951575 2.95194691897677 0.00339192507338279 -105.479361947048 211.558776669724 -0.498581829633651 0.618417608606506 PXN-AS1 other 1 1 1 2.95194691897677 -0.498581829633651 0.863412332426099 0.663657951163311 1.809776012809 0.366707231428727 0.71408518561894 -3.71054501232119 10.6970798176669 -0.346874574703369 0.728918643024539 DENND5B-AS1 other 1 1 1 0.366707231428727 -0.346874574703369 1.67981030379284e-22 102.809925636621 9.80210186156794 10.4885591976674 2.72405226148761e-22 -8.32527214734408 23.9783495786379 -0.347199548494404 0.728671800521812 LINC00346 other 2.47654433088179e-18 1 4.07790623544696e-18 10.4885591976674 -0.347199548494404 0.00132565116158909 -3.96337732799752 6.39637855861437 -0.619628324321082 0.535943445085259 -59.4144974806186 16.9273721892028 -3.50996580074706 0.000512449925760811 MT1JP other 1 1 1 -0.619628324321082 -3.50996580074706 0.254888567873499 14.2004104860016 9.48615614705585 1.49696149482095 0.135388940915526 -10.208713124641 18.8829155940208 -0.540632248966549 0.589137184567911 PAPPA-AS1 other 1 1 1 1.49696149482095 -0.540632248966549 0.00187735228211925 6.28410142802694 38.6925097397444 0.162411316047871 0.871084788120638 -209.178028643202 66.1772690880486 -3.16087429302789 0.001723909383827 CTSO other 1 1 1 0.162411316047871 -3.16087429302789 1.10993630527452e-08 111.669122848385 20.4449815245219 5.46193317486975 9.53271747982245e-08 -73.6304875853479 60.210967973704 -1.22287500206781 0.222285258025728 APOPT1 other 0.000128475127335525 1 0.00118834856103467 5.46193317486975 -1.22287500206781 5.2628897955589e-06 24.1220066969295 7.2918905368119 3.30805935376478 0.00104678224832052 -45.3100732643766 18.1248510451779 -2.49988665569924 0.0129251319623303 TRAPPC2B other 0.0514657993107705 1 1 3.30805935376478 -2.49988665569924 0.27043140187583 -5.4451866814608 4.94569253247856 -1.10099579496745 0.271731164759519 -14.7438068413515 9.75716524844522 -1.51107483228296 0.131762431004836 DNAAF4 other 1 1 1 -1.10099579496745 -1.51107483228296 1.05818295708662e-05 35.4596684031496 7.68297412915628 4.6153569967889 5.73324400285923e-06 1.19755167820351 12.6208232226783 0.0948869702930025 0.924465322233909 URB1-AS1 other 0.100739017514646 1 0.0654163140726239 4.6153569967889 0.0948869702930025 0.0240286865566839 20.9503125637019 10.0017816505704 2.09465806149718 0.036994918225504 -31.6167258040725 24.9186635820135 -1.26879700831523 0.205444342810666 ZNF432 other 1 1 1 2.09465806149718 -1.26879700831523 2.29675903349625e-05 12.2575392322103 2.74782765318986 4.46081078556036 1.13764189031991e-05 -10.2400554096915 13.2918384937486 -0.77040173295121 0.441639031534133 CCND2-AS1 other 0.212101919265357 1 0.12709735198654 4.46081078556036 -0.77040173295121 0.661150928514257 2.65020819872213 7.86994413620498 0.336750573174983 0.736529177095317 -14.4175548819886 19.1196934736665 -0.754068306683151 0.451371515691222 ZNF10 other 1 1 1 0.336750573174983 -0.754068306683151 0.244441812870272 -3.38452121713385 7.70814157208068 -0.439083945914119 0.660898906167088 -29.1031938913074 17.3485870747552 -1.67755412967647 0.0944167182031432 ZNF486 other 1 1 1 -0.439083945914119 -1.67755412967647 2.47353668645623e-06 166.174127761465 61.5343338595505 2.70051071229194 0.00729173163512736 -291.406793871713 89.088504775267 -3.27098085894258 0.00118861962550898 SMIM3 other 0.0248268877219611 1 1 2.70051071229194 -3.27098085894258 6.54594203817383e-17 132.300341905039 30.8412437920658 4.28972134836776 2.37438010113795e-05 -207.069380827376 58.1816769152834 -3.55901362432169 0.00042883409404023 HMBS other 9.21537720134111e-13 1 0.259590976457413 4.28972134836776 -3.55901362432169 7.18013540369405e-11 15.9092089952621 2.34647169509687 6.78005578695265 5.82671486781011e-11 -9.09633510674464 9.88188638155891 -0.920505939404421 0.358004006159158 ZNF225 other 9.02543020244343e-07 1 7.94705640820621e-07 6.78005578695265 -0.920505939404421 0.271124198647829 -0.444093812646529 0.55940064004349 -0.7938743377412 0.427889867944826 3.09640769936463 2.15095846828261 1.43954787831719 0.151027658216386 PPIAL4D other 1 1 1 -0.7938743377412 1.43954787831719 5.45731995819731e-14 31.3283078756844 5.65703715925575 5.53793567087086 6.39010738394812e-08 -32.2460091057658 8.37448043844714 -3.85050861874663 0.000142360104451639 DND1 other 7.36847340755801e-10 1 0.000801638971316292 5.53793567087086 -3.85050861874663 0.0194053781038782 26.001051852429 21.2354231006992 1.22441882740603 0.221720946411648 -37.7026588491955 31.7479347876439 -1.18756256434888 0.235912003165329 SALL3 other 1 1 1 1.22441882740603 -1.18756256434888 0.00430190452294839 17.9006716665875 5.48138714652228 3.26571927654202 0.00121095782162439 -3.28387525513836 12.6416626274112 -0.259766088680286 0.795212308098796 POLG2 essential 1 1 1 3.26571927654202 -0.259766088680286 3.52351394305066e-31 229.183820261514 17.4342478719345 13.1456098333013 7.40986159843436e-32 69.6650409737003 79.3800767098255 0.877613676645356 0.38081182171873 SMIM10L1 other 5.33389540699009e-27 1 1.12763273804974e-27 13.1456098333013 0.877613676645356 0.629340079943745 0.763875262789067 1.38904249557636 0.549929368771479 0.582753848190797 2.97989032121381 3.3421872719811 0.891598847914785 0.373282111625174 LINC02361 other 1 1 1 0.549929368771479 0.891598847914785 0.409489359423238 -10.5840806925292 9.87229069661787 -1.07209978087003 0.284485614365341 -30.5197551778786 28.721845729114 -1.06259728102857 0.288768368188699 CYP2B7P other 1 1 1 -1.07209978087003 -1.06259728102857 0.105360664290097 198.476501916501 107.242235670671 1.85073073752397 0.0651297301003846 236.416003186459 198.264231136588 1.19242892089591 0.233976576759162 MTRNR2L1 other 1 1 1 1.85073073752397 1.19242892089591 1.7276608856053e-21 45.7480582845088 4.52695430369403 10.1057035736319 5.17881336572351e-21 -5.56288383285053 18.4988859876443 -0.300714531489414 0.763828081137442 ZBTB11-AS1 other 2.53240532612025e-17 1 7.72161072829375e-17 10.1057035736319 -0.300714531489414 0.0220873622012411 19.108955629544 6.9860550141555 2.73529990686081 0.00658320898551729 18.7944703072769 17.40521446529 1.07981836964764 0.281043945629134 ZNF350 other 1 1 1 2.73529990686081 1.07981836964764 0.00473737194725074 6.17920686130456 2.06113656404857 2.99796091587794 0.00293079480550247 -5.47783501377295 7.97266732962859 -0.687076832293733 0.492531936772064 PLBD1-AS1 other 1 1 1 2.99796091587794 -0.687076832293733 0.012404313447782 3.98612493322373 5.93945721777661 0.671126129386602 0.502627364417515 -34.3770025390004 13.5658135334255 -2.53409074614635 0.0117535852208196 ZNF253 other 1 1 1 0.671126129386602 -2.53409074614635 0.000255663208827457 44.4171299635157 59.7750974911338 0.743070807539945 0.457987402493915 -510.555831454278 157.571350612507 -3.24015647178031 0.00132107172523245 CAPNS2 other 1 1 1 0.743070807539945 -3.24015647178031 0.0434178660561438 103.563711767756 43.682718432173 2.37081654907904 0.0183522833461075 135.055200937633 103.862926898581 1.30032153888279 0.194444384722707 KHDC1L other 1 1 1 2.37081654907904 1.30032153888279 0.392417549912936 -26.2501810823551 21.4208436716076 -1.22545038303737 0.221309562304344 -62.4566149671752 58.7783264693048 -1.06257899329256 0.288776652296707 HP other 1 1 1 -1.22545038303737 -1.06257899329256 0.0137959042211593 11.7273483241408 4.78070134154881 2.45306022825963 0.0146995128970702 -34.6483914580682 26.847073828682 -1.29058353544108 0.197782737457948 MIR200CHG other 1 1 1 2.45306022825963 -1.29058353544108 2.25111629715216e-07 174.173785371062 55.1740597740735 3.15680568158784 0.00174739509740284 -312.389196837789 120.517330860647 -2.59206866437327 0.00997897329419498 KIAA1147 other 0.00243593294514835 1 1 3.15680568158784 -2.59206866437327 9.96770450884653e-17 538.107845669461 68.4728459590605 7.85870425177293 5.96361084814563e-14 -501.351461859949 204.64040448206 -2.44991434183713 0.0148244199805844 LSM14A other 1.40066183758311e-12 1 8.50887995813418e-10 7.85870425177293 -2.44991434183713 0.616820737527953 -1.57297840409025 3.72481943612158 -0.42229655183718 0.673093949563821 -9.80142983519732 10.0552334165017 -0.974759056225603 0.330420691863924 NHLRC4 other 1 1 1 -0.42229655183718 -0.974759056225603 0.533375242646883 -30.518603344038 29.9737862728517 -1.01817645145751 0.309363274430659 -45.956431664837 73.5380243774836 -0.624934271132095 0.532459552340006 TMPO-AS1 other 1 1 1 -1.01817645145751 -0.624934271132095 2.21232579184477e-06 287.968233337128 58.2551695175867 4.94322196161823 1.24387624223505e-06 -151.380485244077 161.183438382972 -0.939181387137287 0.348348198202128 GATC other 0.0222714837465013 1 0.0147648109953301 4.94322196161823 -0.939181387137287 0.460711464657714 -2.4605390808621 1.98614045777034 -1.23885451869015 0.216307312960253 -0.356657027965954 4.8056669203981 -0.074215927544227 0.940884943375583 LINC01619 other 1 1 1 -1.23885451869015 -0.074215927544227 1.41038611499485e-24 113.081438690804 16.2442355894553 6.96132717775951 1.96546064816732e-11 -110.224455367617 29.0358469234018 -3.79615086339294 0.000176263651148474 ZNF271P other 2.09837246188934e-20 1 2.7040807597486e-07 6.96132717775951 -3.79615086339294 0.19913037816115 38.6843667598249 23.71012743286 1.63155456963981 0.103757052351888 -59.2389933631234 80.5203503969546 -0.735702130841248 0.462450891297793 ZBED6 other 1 1 1 1.63155456963981 -0.735702130841248 0.04276594853159 11.9599964095065 4.84056320698962 2.47078612510144 0.0140039243227417 7.99615002965102 10.5548380813895 0.75758149656033 0.449260805817678 MGAM other 1 1 1 2.47078612510144 0.75758149656033 2.93751709803943e-18 151.854255993785 17.4415884329791 8.70644646714938 1.75437020189459e-16 -106.192016905142 58.3347718993713 -1.82038968264632 0.069642494356066 FNTB other 4.19888693993756e-14 1 2.55524019905948e-12 8.70644646714938 -1.82038968264632 0.95035365925627 -25.2516290031886 79.1629874958928 -0.318982769624489 0.749948344809008 -15.8168360889613 214.897092764879 -0.0736019081759596 0.941373282064043 KRT73-AS1 other 1 1 1 -0.318982769624489 -0.0736019081759596 0.535491415264601 3.2995931451116 2.96230106819156 1.11386151142495 0.266193214265101 2.76251709029751 6.33130388908712 0.436326724904027 0.662900502228994 ZNF625 other 1 1 1 1.11386151142495 0.436326724904027 0.111316342203182 -25.7374406160923 29.4167432416521 -0.874924882223191 0.382270977278914 -144.670888280301 71.1767737015698 -2.03255754309513 0.0429226103176844 GALNT4 other 1 1 1 -0.874924882223191 -2.03255754309513 0.121391122852221 29.9371086498446 16.0908942281903 1.86049999616532 0.0637377446062272 -22.9297881419947 49.9008740141357 -0.459506744020139 0.646184279480619 PSMA3-AS1 other 1 1 1 1.86049999616532 -0.459506744020139 0.915651761428069 49.3522778050657 145.695329050457 0.338736170381785 0.735031344878274 -69.0971510373704 399.306631082614 -0.173042833899432 0.862727502623318 KRT7-AS other 1 1 1 0.338736170381785 -0.173042833899432 2.33121052628662e-06 37.7714061494513 7.68107332386553 4.91746459861194 1.40399384595261e-06 -43.8535887495486 31.7842073221362 -1.37972887934841 0.168633435033554 LBX2-AS1 other 0.0234403218418119 1 0.0166106511914654 4.91746459861194 -1.37972887934841 0.0028190949334175 40.2484897534069 19.9872585256929 2.01370736770473 0.0448770143816381 -101.321947870696 45.2653101467476 -2.23840171518137 0.0258822346596522 INAFM1 other 1 1 1 2.01370736770473 -2.23840171518137 0.0369404108109047 136.191548915793 53.5417353467581 2.54365212546363 0.0114401017343574 8.4641484118685 152.973469754585 0.0553308258317439 0.955909433735378 CNPY2 other 1 1 1 2.54365212546363 0.0553308258317439 2.48256859028452e-08 7.62573919393372 1.25317103511393 6.08515436461589 3.38570734118819e-09 5.27989833514792 7.23680451356953 0.72958974161147 0.466184888918314 LINC01481 other 0.000282839039491116 1 4.44069374870243e-05 6.08515436461589 0.72958974161147 3.46270764812545e-20 989.731623616026 105.559048300011 9.37609460823378 1.29125512567333e-18 -637.821885273983 433.933808103716 -1.4698598573392 0.142582196874614 CUX1 other 5.03131421272628e-16 1 1.90434305934303e-14 9.37609460823378 -1.4698598573392 0.0654226455252146 45.0991670399304 21.6380852848326 2.08424943548693 0.0379353077952168 -38.9903705404337 53.27150596941 -0.731917933065813 0.464757708448412 TEN1 essential 1 1 1 2.08424943548693 -0.731917933065813 6.19581366091423e-06 687.955493395497 150.780003524832 4.5626440994359 7.20790568116053e-06 -518.386211681658 285.756820865586 -1.81408167305128 0.0706015845792383 P2RX5-TAX1BP3 other 0.0602418962250691 1 0.081716026707317 4.5626440994359 -1.81408167305128 0.148435557704745 4.39866959486393 2.98276091344822 1.47469734333445 0.141280149807911 -7.65614646485477 8.01422693168399 -0.955319400126597 0.340139575491628 BCDIN3D-AS1 other 1 1 1 1.47469734333445 -0.955319400126597 0.199787204386412 21.8141137413298 12.1985619968378 1.78825288972459 0.0746841583860836 13.89329053705 32.9576235155741 0.421550131807433 0.673637327662165 MAP1LC3B2 other 1 1 1 1.78825288972459 0.421550131807433 0.0528726828501713 22.2442605445809 9.1818869263607 2.4226240992708 0.0159654539564705 19.0355837816367 20.0561008046257 0.949116878054698 0.343279645295494 CLEC5A other 1 1 1 2.4226240992708 0.949116878054698 1.00042222459375e-16 384.990596907486 43.6758391466736 8.81472696184722 8.09580959987477e-17 -17.1207267954213 146.077298172988 -0.117203200015012 0.906773252522488 CHURC1 other 1.40569326777668e-12 1 1.18101670442973e-12 8.81472696184722 -0.117203200015012 0.0537386122495056 28.6589895433332 12.7018195447021 2.25629008839815 0.0247313320204486 -15.7152033864692 41.2657672662729 -0.38082906068521 0.703584375336298 VASH1-AS1 other 1 1 1 2.25629008839815 -0.38082906068521 9.536416869439e-07 384.06948409596 73.2424418442368 5.24381047962264 2.86473316556347e-07 -136.256207107032 139.805022873292 -0.974615963766359 0.330486954983453 C17orf49 other 0.00989307886035602 1 0.00350213629490134 5.24381047962264 -0.974615963766359 6.22227176792127e-19 7.80999250127049 0.806061961702127 9.68907214623856 1.35616097690422e-19 -0.00155246208284949 3.94586262458997 -0.0003934404794467 0.999686329760453 ITFG2-AS1 other 8.95073793815474e-15 1 2.00847440679515e-15 9.68907214623856 -0.0003934404794467 2.43246704301523e-05 50.0694758406327 15.9169371933799 3.14567276557813 0.00181368163721 -190.79226515651 71.910486848305 -2.65319112021847 0.00837386388566883 RTEL1 other 0.223981565320843 1 1 3.14567276557813 -2.65319112021847 8.72459314832077e-16 187.745566468602 26.2910071110665 7.14105647134285 6.26649373848959e-12 -126.440573113172 60.5703512067874 -2.08749942164778 0.0376337350197362 PPT2-EGFL8 other 1.21324192320549e-11 1 8.69476006215431e-08 7.14105647134285 -2.08749942164778 0.0206834119907443 9.29073237927609 3.3189595263946 2.79929065280547 0.00543537919571436 6.92289865054463 9.96595194120251 0.694655030587003 0.487780326552889 MEG8 other 1 1 1 2.79929065280547 0.694655030587003 1.00919633961843e-07 45.016589785986 11.7245344727954 3.83952044240551 0.000148672829397718 -80.1070581251241 31.9795621251635 -2.50494543394923 0.0127453251571177 PDF other 0.00111334540186705 1 1 3.83952044240551 -2.50494543394923 0.121824604059488 5.40195148978508 3.93174996248608 1.37393057578091 0.170433945794263 -13.2422167759261 10.9675308466516 -1.20740182645293 0.22817753561889 LINC00641 other 1 1 1 1.37393057578091 -1.20740182645293 1.9252279867528e-05 11.1596435898028 2.49529762870554 4.47226954469235 1.080693022501e-05 -4.23268247099068 7.61045723186835 -0.556166645713029 0.578490534771507 LINC00640 other 0.178930689088805 1 0.120940356148087 4.47226954469235 -0.556166645713029 0.856650591023923 -6.02107050521 11.5598019673533 -0.520862772754624 0.602822595933281 -8.40651385214343 22.4979671218289 -0.373656597799315 0.708907250947969 SPESP1 other 1 1 1 -0.520862772754624 -0.373656597799315 0.000660398504695768 13.8043544807531 3.65764822904164 3.77410664348388 0.000191646535432834 21.1720236728655 10.9829439553459 1.92771844770818 0.054783323687019 MIR1247 other 1 1 1 3.77410664348388 1.92771844770818 4.29154778759602e-06 116.86464383836 28.9858734339189 4.03177927706007 6.92983490100167e-05 -193.31840461353 86.7984960680373 -2.22720914959168 0.0266307994358724 SPECC1L-ADORA2A other 0.042281325163573 1 0.730543195263596 4.03177927706007 -2.22720914959168 4.20194389712034e-11 45.4846779371512 12.4574545016347 3.65120161034363 0.000304787971550588 -88.538183553449 24.7822881086576 -3.57263958700079 0.000407759407431452 TRIM6-TRIM34 other 5.32344272326176e-07 1 1 3.65120161034363 -3.57263958700079 1.13058754526591e-12 212.048448367827 33.5960973211093 6.31169883635833 9.19730999227224e-10 -262.060893004519 92.1457316652085 -2.84398298508997 0.00474207764233442 BCL2L2-PABPN1 other 1.48751403330636e-08 1 1.22544958337035e-05 6.31169883635833 -2.84398298508997 3.18102256630287e-10 172.617839814137 27.4968621577651 6.27772866677406 1.12918049931979e-09 -95.9054204839401 82.9386891831697 -1.1563411651242 0.248412336383874 SYNJ2BP-COX16 other 3.91997410845503e-06 1 1.500680883596e-05 6.27772866677406 -1.1563411651242 5.70668632441682e-12 39.3655007050453 10.1574314615436 3.87553692624799 0.000129083329436341 -74.1050220525064 20.206727858479 -3.66734399411486 0.000286912851313267 TRIM34 other 7.38787611559001e-08 1 1 3.87553692624799 -3.66734399411486 0.459712384188044 0.589247419676841 1.74763100867579 0.337169240389779 0.736211751513487 -5.796029437552 5.33799294824396 -1.08580687418456 0.27838685433177 LINC01269 other 1 1 1 0.337169240389779 -1.08580687418456 0.00329320118516916 5.31591432126176 1.55773448797098 3.41259332852416 0.000729501708110625 4.35714191666773 4.60115942179681 0.946966083380395 0.34439840988572 LINC00638 other 1 1 1 3.41259332852416 0.946966083380395 0.00497085784958803 5.61980169030029 1.72099911410737 3.26542974033725 0.00121532770902959 6.061750292463 5.56260733538647 1.0897318338293 0.276677649274502 SLC25A21-AS1 other 1 1 1 3.26542974033725 1.0897318338293 0.0195167772858814 22.1740117386715 19.3139985545668 1.14807980729751 0.25179314991078 -85.0645348312699 39.9516676248601 -2.12918608629839 0.0340020490431915 PRC1-AS1 other 1 1 1 1.14807980729751 -2.12918608629839 6.32643431769283e-08 40.2382336391902 7.94359576290158 5.06549361777849 6.92835173916025e-07 -46.7844892109944 26.1869524009412 -1.78655723257484 0.074964610539422 HIF1A-AS1 other 0.00070520763339322 1 0.00831540775734013 5.06549361777849 -1.78655723257484 0.731950560005105 4.62204542413933 16.5989697146107 0.278453753673092 0.780844469177529 36.5370010280458 46.7634779042277 0.781314877881286 0.435196782345361 RNASE4 other 1 1 1 0.278453753673092 0.781314877881286 0.000910144915096065 40.6249682763075 11.2182147199645 3.62133987362615 0.000340805311466246 17.8495591717651 28.6453114987992 0.623123235106497 0.533648776044425 MC1R other 1 1 1 3.62133987362615 0.623123235106497 0.154432937752463 3.49750957674644 1.85885510620444 1.88153964506031 0.0608118233725169 5.27055867072566 6.04836329883078 0.871402462174275 0.384191834323422 TGFB3-AS1 other 1 1 1 1.88153964506031 0.871402462174275 0.00175100878894385 67.5817491811841 19.4398179911826 3.47645997569717 0.000578725798759847 -23.0688906821094 44.8338374965412 -0.514541961389968 0.607230547288094 CEP95 other 1 1 1 3.47645997569717 -0.514541961389968 2.63545412166936e-07 28.3749556720121 5.15176816549672 5.50780911727543 7.50523396755292e-08 6.77425281906612 15.1356159315002 0.447570343336182 0.654768036564454 FOXN3-AS1 other 0.00284181017939607 1 0.000939730345077301 5.50780911727543 0.447570343336182 2.40274588399338e-07 571.236554922361 151.490853166651 3.77076597683398 0.000193909667467956 -814.778153335025 386.826494812473 -2.1063142371621 0.0359579231463497 TUBB3 other 0.00259592665306645 1 1 3.77076597683398 -2.1063142371621 1.60992625032819e-19 56.7192980455648 22.1159938892865 2.56462803930512 0.0107873926436911 -299.772503363818 40.0793535754841 -7.47947450797171 7.33589178614054e-13 UBE2F-SCLY other 2.32730938747443e-15 1.12444549297962e-08 1 2.56462803930512 -7.47947450797171 2.91400291534975e-05 57.4505406148831 15.3361935496049 3.74607561055222 0.000213116810434136 -78.0500890981904 32.0666867776725 -2.43399293601281 0.0154817362937916 TVP23C-CDRT4 other 0.26668954681281 1 1 3.74607561055222 -2.43399293601281 0.0273616391255583 3.35623948593582 2.75510450854932 1.21818953710145 0.224049353412276 -11.2307763048885 5.81053677388014 -1.93282939975076 0.0541393438500555 FPGT-TNNI3K other 1 1 1 1.21818953710145 -1.93282939975076 2.35984453523001e-05 767.620531423637 206.178120069713 3.72309404685661 0.00023259553246405 -468.920066403683 461.145300565555 -1.01685968788708 0.309990778733217 BLOC1S5-TXNDC5 other 0.21771925682032 1 1 3.72309404685661 -1.01685968788708 0.119895467584188 -24.1773165974895 28.8621820099394 -0.837681523495468 0.402834799489303 -139.932567532189 69.8349569352124 -2.00376106284432 0.0459383019434821 POC1B-GALNT4 other 1 1 1 -0.837681523495468 -2.00376106284432 4.97085621688193e-29 493.620675820258 46.2011649309608 10.6841608119164 5.95011438278483e-23 -151.391667998918 149.617024684886 -1.01186123917228 0.312378544337949 NDUFC2-KCTD14 other 7.49555408943627e-25 1 8.92398155130068e-19 10.6841608119164 -1.01186123917228 0.00104610415831067 5.46372127879112 1.90821564429412 2.86326196681625 0.00446972371928666 -11.5015680572017 6.29545227221418 -1.82696453882518 0.0686364509760165 LRP1-AS other 1 1 1 2.86326196681625 -1.82696453882518 0.221507976959926 8.71780312040218 9.66712091816893 0.901799325176274 0.367843849694206 -32.818387113969 23.142720276125 -1.41808684209979 0.157141529220485 ITGB3 other 1 1 1 0.901799325176274 -1.41808684209979 0.767943375184119 2.54360958501307 4.16671252137363 0.610459582216275 0.541992071820815 -1.19323600839786 8.39842329230183 -0.142078574378551 0.887107630981412 LINC02345 other 1 1 1 0.610459582216275 -0.142078574378551 0.00174373347010424 13.2455763123114 4.31749678501055 3.06788330643286 0.00234294228427684 -11.3162279009647 12.7949192547204 -0.884431364956825 0.377137961652882 LINC02323 other 1 1 1 3.06788330643286 -0.884431364956825 0.962629445270293 0.0973556205944187 1.05639024312292 0.0921587654071987 0.926629565580642 -0.426008315028896 2.06027597198589 -0.206772452244962 0.83631907703451 ANKRD34C-AS1 other 1 1 1 0.0921587654071987 -0.206772452244962 0.000428717866522153 25.1724079052148 8.13463173864212 3.09447418321813 0.00214561638242642 -19.9326524537203 15.9180897244474 -1.25220128789118 0.211410953128138 USP3-AS1 other 1 1 1 3.09447418321813 -1.25220128789118 0.00211734919223226 60.4203569836969 35.1239631496931 1.72020329044859 0.0863622672565473 -151.309574629924 70.2511427058941 -2.15383791354655 0.0319993577091094 BUB1B-PAK6 other 1 1 1 1.72020329044859 -2.15383791354655 0.00071632857733052 47.7459393370914 16.9648061383519 2.81441113725158 0.00519021715199547 -60.2924517688266 35.1604861987487 -1.71477867023842 0.0873569950880213 ZNF710-AS1 other 1 1 1 2.81441113725158 -1.71477867023842 4.70055544942026e-17 71.361675334064 7.75529144353801 9.20167550808488 4.7549169008543e-18 9.53579673981476 43.8530103705222 0.217449079532854 0.827997402877236 ZHX1-C8orf76 other 6.62919335031739e-13 1 6.98972784425582e-14 9.20167550808488 0.217449079532854 0.00209456293326171 29.1921963104927 15.5654604958295 1.8754470077075 0.0616445026561024 -65.0556168873464 30.4548547012136 -2.13613289328069 0.0334294693835402 ST20-MTHFS other 1 1 1 1.8754470077075 -2.13613289328069 1.03758264378678e-08 431.31333992 72.4362500935485 5.95438526101194 6.96442730220367e-09 -279.200976489434 395.829079834959 -0.705357414886868 0.481109097512773 TGIF2-C20orf24 other 0.000120307707547077 1 9.04679106556256e-05 5.95438526101194 -0.705357414886868 0.0329335448842095 3.0096048670458 2.85125482014539 1.05553696771737 0.291986140214864 -10.5766500308113 5.61402877073399 -1.88396790660345 0.0604872229056609 UBE2Q2P2 other 1 1 1 1.05553696771737 -1.88396790660345 6.43117321263528e-09 103.80087547992 18.2302148965751 5.69389203960623 2.81158162817914e-08 -65.0115572648892 49.9889103708949 -1.30051959089592 0.194358757526429 THTPA other 7.53090383199592e-05 1 0.000357745646369514 5.69389203960623 -1.30051959089592 0.0353173903267645 1.20775701590819 0.598832843726836 2.0168516616285 0.044545864870135 -3.07261654170536 2.76449889424457 -1.1114551530848 0.267206847598837 ADNP-AS1 other 1 1 1 2.0168516616285 -1.1114551530848 0.000433719331577931 60.1673745260623 18.745802469608 3.20964517915996 0.00146376104093053 -51.0886572797947 38.0702381605489 -1.34195791117316 0.180561039978153 MRPL46 other 1 1 1 3.20964517915996 -1.34195791117316 0.000220897954922966 11.7595022582811 5.85931450444537 2.00697577325118 0.0456009561246042 -31.6477150426361 12.241928391131 -2.58519034187165 0.0101788307989819 ANP32AP1 other 1 1 1 2.00697577325118 -2.58519034187165 0.0331532836765625 1.2222743830249 0.91377419939352 1.33761095885191 0.181976150433139 -2.76910866815478 1.82439129140826 -1.51782607228809 0.130048634038767 INO80-AS1 other 1 1 1 1.33761095885191 -1.51782607228809 0.0179544273825103 8.24343276055916 6.33863505260268 1.30050597520587 0.194363415473066 -23.5263417858519 12.3477670219118 -1.90531144166416 0.0576357246903523 IQCH-AS1 other 1 1 1 1.30050597520587 -1.90531144166416 0.877307845588311 -5.70369799786783 28.5728935481236 -0.199619194613995 0.841905201596166 32.1931142429302 78.5816273299174 0.409677367812332 0.682316737055341 HSP90B2P other 1 1 1 -0.199619194613995 0.409677367812332 0.00277205299541984 3.50792047837021 1.09277417498396 3.21010558144064 0.00146149228741419 -0.758883488273328 2.26506369875507 -0.335038475381698 0.73781557884507 CRTC3-AS1 other 1 1 1 3.21010558144064 -0.335038475381698 0.176948566186005 13.3154214295446 7.27193536497397 1.83106982684138 0.068019807553584 9.32364862996091 18.5662208157235 0.50218343961873 0.615883864448843 SLC22A31 other 1 1 1 1.83106982684138 0.50218343961873 0.0170733860906775 -25.7546089143648 9.00748419639273 -2.85924552881023 0.00452614837677863 -34.8119993529749 31.3878931615958 -1.10909002951395 0.268226771166638 IL21R-AS1 other 1 1 1 -2.85924552881023 -1.10909002951395 1.08119803655878e-20 382.168534043723 85.4193401416215 4.47402816985128 1.06912914237602e-05 -663.89961216015 121.212886790935 -5.47713720658453 8.7771402458082e-08 RBM15B other 1.57703545612464e-16 0.00132701583376374 0.119689007488995 4.47402816985128 -5.47713720658453 0.00680830679778208 51.8527436818521 16.4573047046792 3.15074336972744 0.00178244327646551 15.9122385685211 68.8065754883217 0.23126043485803 0.817260279745689 MIR568 other 1 1 1 3.15074336972744 0.23126043485803 0.544164062134112 7.6852104472049 18.7727327814269 0.409381550181569 0.682535280059295 46.9685985163432 44.7749677020624 1.0489923483335 0.294978215040436 HOXB7 other 1 1 1 0.409381550181569 1.0489923483335 4.60035476941896e-17 1426.3294113657 160.712124065328 8.87505793144711 5.37466414077642e-17 -653.140472787516 878.214044831763 -0.743714447100007 0.457603614560604 NORAD other 6.48880040226544e-13 1 7.84969697760396e-13 8.87505793144711 -0.743714447100007 0.0476621382580074 49.1228441100084 22.2652799138282 2.20625315738788 0.0280923214445847 -35.1633593039002 76.6187140828581 -0.458939564893681 0.646596100373296 MIR762HG other 1 1 1 2.20625315738788 -0.458939564893681 0.0774356770358322 2.43359491321519 1.11471541449817 2.18315354893586 0.0297553444996521 5.11283921554192 4.41362195681018 1.15842255308089 0.247560861963866 SPDYE6 other 1 1 1 2.18315354893586 1.15842255308089 0.538627966687748 -0.656292496719549 3.96921435556933 -0.165345692605058 0.868776629658305 -9.21125225087051 8.27550248183542 -1.11307467686573 0.26651439498486 CCDC187 other 1 1 1 -0.165345692605058 -1.11307467686573 0.00045784094981053 75.2785436576805 26.5024861059176 2.84043328451635 0.00479383932110763 -67.4215937630874 58.319716340851 -1.15606861612701 0.248515471462057 JHDM1D-AS1 other 1 1 1 2.84043328451635 -1.15606861612701 0.000288410735144331 69.0481191783027 17.3642111430537 3.97646162036704 8.65296142478952e-05 -62.9628466200629 60.4634651182069 -1.04133705365661 0.298505249149826 PMF1-BGLAP other 1 1 0.903369172748026 3.97646162036704 -1.04133705365661 0.00117898576571896 148.968792051994 40.1450878041702 3.71076015024981 0.000243607558159335 112.273169754058 113.232482527214 0.991527936580159 0.322177000731393 SNHG19 other 1 1 1 3.71076015024981 0.991527936580159 0.236709342143626 2.71074940077261 32.3348612708943 0.0838336487069652 0.933241443416329 -188.699542630729 117.139923987674 -1.61089008945051 0.108195775217383 SLX1B-SULT1A4 other 1 1 1 0.0838336487069652 -1.61089008945051 0.0355866309603619 -0.463686959480399 2.19786088140649 -0.210971933393559 0.833043877691614 -14.156901039065 5.45286322191934 -2.59623255946661 0.00986136156085426 TBC1D3G other 1 1 1 -0.210971933393559 -2.59623255946661 0.211266482009254 -30.3637067729444 71.4350506689349 -0.425053338502757 0.671083467417826 180.839615910041 142.851878807875 1.26592395857289 0.206461149333765 MRC1 other 1 1 1 -0.425053338502757 1.26592395857289 0.231900765853337 6.33994047734833 3.9878820559745 1.58980140043261 0.112870112632002 -8.77789186440395 19.6499904760688 -0.446712270679944 0.655385932464035 SCX other 1 1 1 1.58980140043261 -0.446712270679944 0.102270217799641 54.8842581538892 25.6513753364071 2.13962243482483 0.0331462029456416 45.3675390467096 91.0784396917155 0.498115022614252 0.618747281931591 ATP2A1-AS1 other 1 1 1 2.13962243482483 0.498115022614252 0.544834821522258 7.38293440085759 6.69658212279242 1.10249292332713 0.271075903701836 7.94644461341779 17.0991194773706 0.464728293403314 0.642442090635353 C16orf95 other 1 1 1 1.10249292332713 0.464728293403314 0.0985728865480802 2.76667066954253 10.442441572192 0.264944807247964 0.791222559472514 -40.8738287875232 19.3054782619158 -2.11721399661752 0.0350128784818461 KCNJ18 other 1 1 1 0.264944807247964 -2.11721399661752 0.0737774053818517 10.041365245498 23.4802263878573 0.427651977439657 0.669192159602569 -112.488980744149 62.1380563254376 -1.81030736067776 0.0711860169874884 MT1L other 1 1 1 0.427651977439657 -1.81030736067776 0.123293832942441 6.00851033258396 2.96171878580198 2.02872411836932 0.0433141007302009 9.07185035859409 7.53560297635063 1.20386522313672 0.229531436225211 SNAI3-AS1 other 1 1 1 2.02872411836932 1.20386522313672 0.0239131098680057 -2.71146118634646 9.67322126977268 -0.28030591989241 0.779423930419206 -43.4305105255564 16.9717090588448 -2.55899452288352 0.0109571962851763 LINC01963 other 1 1 1 -0.28030591989241 -2.55899452288352 0.621458746404094 -2.63443509900012 2.80736369385123 -0.938401784125846 0.348763837904961 -5.05654999874631 9.65762320486653 -0.523581205383773 0.600941543152036 FBXL19-AS1 other 1 1 1 -0.938401784125846 -0.523581205383773 0.0712304829610128 2.84812021361139 1.66166240234745 1.71401856934827 0.0874936515028906 -2.64206618461612 3.27615112018413 -0.806454308025825 0.420579875427879 ADPGK-AS1 other 1 1 1 1.71401856934827 -0.806454308025825 0.0432957909846852 2.72504874665808 2.06061837450781 1.32244222431967 0.1869653176367 -4.88237217160939 3.73191758897095 -1.30827438045213 0.19171918682565 CAPN10-AS1 other 1 1 1 1.32244222431967 -1.30827438045213 0.000450065891354961 5.07752742757099 1.55372873009868 3.26796263029037 0.00120171257789313 -3.07031898389683 4.29649353835704 -0.714610404155502 0.475374063255186 LINC01572 other 1 1 1 3.26796263029037 -0.714610404155502 0.517550554986644 52.4215213794525 137.425416717643 0.381454338153174 0.703125788114407 -327.362000624813 315.832984013444 -1.03650352304837 0.300769953626519 WFDC21P other 1 1 1 0.381454338153174 -1.03650352304837 3.51471496097624e-14 24.8983010497558 3.319029631278 7.50168085729585 7.40420033509196e-13 -10.0232656489222 6.90053604466425 -1.45253435154108 0.147412289366041 LMO7-AS1 other 4.76032994314621e-10 1 1.04088248310723e-08 7.50168085729585 -1.45253435154108 0.0455537870456793 -156.727724010398 71.0526524257607 -2.20579695000344 0.0281086479647408 -321.207665736756 156.354031020894 -2.05436126999395 0.0407526045710795 TMEM178B other 1 1 1 -2.20579695000344 -2.05436126999395 0.000722160399686456 837.397940710904 246.160159084748 3.40184188954235 0.00075428120807562 -1676.18642795208 1212.93326786942 -1.38192798594468 0.16795773511089 EPPK1 other 1 1 1 3.40184188954235 -1.38192798594468 0.699488851550993 -6.54683595918825 7.97172114182506 -0.821257523025875 0.41211101101785 -3.86160413298063 20.3550721464919 -0.189712131953615 0.849654992873428 LINC02188 other 1 1 1 -0.821257523025875 -0.189712131953615 0.103827035978255 -6.80125621520417 14.6286744324101 -0.464926350410525 0.642301390329361 -61.1443347804995 29.2068065141792 -2.09349607430772 0.0370941871236243 SPINT1-AS1 other 1 1 1 -0.464926350410525 -2.09349607430772 1.21658305216686e-05 56.5962045665403 16.309695852645 3.47009564604247 0.000591629274194276 -105.99145743011 44.3162944929504 -2.39170396899883 0.0173473848652777 ZNF865 other 0.115307741684375 1 1 3.47009564604247 -2.39170396899883 0.414530651651713 19.4630347081267 17.7923270963931 1.09390045510529 0.274821379694707 -11.7790493261045 41.7136867363808 -0.282378524836341 0.777835830971237 MUC22 other 1 1 1 1.09390045510529 -0.282378524836341 0.0861088959758882 -0.735984347319239 28.1159832729556 -0.0261767244692869 0.979133169064033 -206.686139080125 96.6559535873434 -2.13836945794914 0.0332657253725221 PYCARD-AS1 other 1 1 1 -0.0261767244692869 -2.13836945794914 0.239468681122835 -155.024257844021 107.954957028331 -1.43600870317922 0.1519828256187 180.308453030807 248.975324900139 0.724202099557964 0.469474119063912 PECAM1 other 1 1 1 -1.43600870317922 0.724202099557964 5.58399522377062e-05 66.9181182659251 20.9551239006339 3.19340122173655 0.00154637607896253 -75.9171565923406 53.5081620929689 -1.4187958177378 0.156934828129965 VPS9D1-AS1 other 0.495467896205167 1 1 3.19340122173655 -1.4187958177378 9.50542119519226e-06 14.0652438950968 3.26593484809338 4.30665170902228 2.2071504045631e-05 -3.75242781283111 6.43915159656613 -0.582751897755009 0.560470740676086 TMEM202-AS1 other 0.0909003428896236 1 0.241903684340116 4.30665170902228 -0.582751897755009 7.87673315543284e-05 16.2894042830934 4.48778775609417 3.62971806342073 0.000330513287146888 -2.69349578198003 10.0153900679423 -0.268935684352574 0.78815357427175 LINC01003 other 0.686299759832864 1 1 3.62971806342073 -0.268935684352574 0.090412719095457 3.01499527414129 2.94803080972476 1.02271498119885 0.307215146538314 17.6443988210226 8.04144433819063 2.19418279589717 0.0289408400665645 SMG1P7 other 1 1 1 1.02271498119885 2.19418279589717 0.364752961866567 0.62725739575436 1.63308521132888 0.384093488449353 0.701168300520669 7.75697583699251 5.55023883416108 1.39759316108151 0.163218770160279 TPBGL other 1 1 1 0.384093488449353 1.39759316108151 0.287819407516248 -2.48350545771809 1.57217099576242 -1.57966624776316 0.115177457919428 -2.01421187895339 3.10167526665449 -0.649394828855166 0.516551969461421 C15orf65 other 1 1 1 -1.57966624776316 -0.649394828855166 0.742588252115481 -2.37793088503987 7.00925217107708 -0.339256004349814 0.734640111017272 -14.4528504521339 18.9270337250315 -0.763608849759673 0.445664756539333 SSTR5-AS1 other 1 1 1 -0.339256004349814 -0.763608849759673 0.0580108919132485 42.3054698594582 41.968648660789 1.00802554309984 0.314208589648063 -275.47255276431 152.003382592948 -1.81227909580145 0.0708861048707344 BOLA2-SMG1P6 other 1 1 1 1.00802554309984 -1.81227909580145 0.209323761340153 -89.3661365425278 50.4067580580706 -1.77289990440517 0.0772025066290196 -64.7437404572905 99.4455406965039 -0.651047196323069 0.515486182018655 DNAAF4-CCPG1 other 1 1 1 -1.77289990440517 -0.651047196323069 2.90934097164165e-21 300.925170609533 29.3553820542618 10.251107277476 1.64557252050337e-21 -31.3088951445785 117.788213191709 -0.265806690637382 0.790559258358254 ISY1-RAB43 other 4.25840238019188e-17 1 2.45848534563204e-17 10.251107277476 -0.265806690637382 0.922921479262561 -1.85915209295131 10.8931976179744 -0.170670923098247 0.864590387291744 -8.56785804494672 21.4228813213826 -0.39993957471981 0.68946785459624 LOXL1-AS1 other 1 1 1 -0.170670923098247 -0.39993957471981 0.409588836161892 -2.0611017953452 32.8422091571995 -0.0627577086997929 0.94999862426464 -124.526088063548 95.5755791169403 -1.30290696864296 0.193543304090721 MIA other 1 1 1 -0.0627577086997929 -1.30290696864296 0.000892952147054524 558.97590587454 149.148773897158 3.74777405987908 0.000211850985169524 403.340119255925 225.769131311743 1.78651579563812 0.0749683224853097 PCDHGA9 other 1 1 1 3.74777405987908 1.78651579563812 0.719320943435347 -19.125627033481 29.1769506506968 -0.655504657167601 0.512615337011925 -41.4626076057642 68.2700667327993 -0.607332167522903 0.544062553236517 GFY other 1 1 1 -0.655504657167601 -0.607332167522903 0.237081779155726 7.6414500678178 13.56380861856 0.5633705312947 0.573582133838117 -39.6120195921665 25.1009380723881 -1.57810913193484 0.115541029487257 SNORD3B-2 other 1 1 1 0.5633705312947 -1.57810913193484 0.000396386426989477 575.601316194037 145.038986597852 3.96859720062717 8.94106005448118e-05 413.474427047611 223.676859630998 1.84853465722706 0.0654532155008609 PCDHGB3 other 1 1 0.931747868277484 3.96859720062717 1.84853465722706 0.000499455146947196 70.4470153964858 28.5239085579844 2.46975323361729 0.014045297068546 -193.484845827901 83.9269303807037 -2.30539643175591 0.0217877288499485 CORO7 other 1 1 1 2.46975323361729 -2.30539643175591 0.779468121383177 -2.24166826209431 28.3963613619783 -0.0789420952043465 0.937129286739192 247.388199645711 369.832855363812 0.668918934750537 0.504041825522527 MMP12 other 1 1 1 -0.0789420952043465 0.668918934750537 0.431873102532768 3.92637490145569 3.02597931267031 1.29755510390149 0.195377782858969 3.0376990515952 8.90636570059863 0.341070550403182 0.73327500268939 LINC01569 other 1 1 1 1.29755510390149 0.341070550403182 0.000496095011864738 552.040847108288 141.532776435085 3.90044526090029 0.000117181654807058 412.306025616776 223.799190651179 1.84230347043305 0.066361619986587 PCDHGA4 other 1 1 1 3.90044526090029 1.84230347043305 0.960688406764806 -3.03269690192084 52.9578765097975 -0.0572662104637026 0.954369329620126 -30.4108226582875 110.934003795842 -0.274134364736841 0.784160477625219 SPON1 other 1 1 1 -0.0572662104637026 -0.274134364736841 7.66908361242089e-12 212.712212697732 29.7565439324659 7.14841794734274 6.0162229463149e-12 -97.1998500905824 56.6094378522244 -1.71702553104867 0.0869451228069448 OVCA2 other 9.89618549346792e-08 1 8.34931420489582e-08 7.14841794734274 -1.71702553104867 0.0073765654705123 305.515107133544 106.9714986522 2.85604213255792 0.00457000501097536 -160.400311439368 240.25540343633 -0.667624158063425 0.504854716310996 MRPL12 essential 1 1 1 2.85604213255792 -0.667624158063425 4.74653888744873e-05 31.5686599036463 7.00525430141782 4.50642596904113 9.25697047791567e-06 9.17976018648515 13.3716150524549 0.686510952526998 0.492888105038227 ALOX12P2 other 0.424720299648913 1 0.104214973640375 4.50642596904113 0.686510952526998 5.01176713238406e-11 614.88936551334 103.930414792974 5.91635631146262 8.55436276181131e-09 -815.807215794387 359.704305324487 -2.26799402653369 0.0240042590873374 GTF2I other 6.33236777176726e-07 1 0.000110719117226124 5.91635631146262 -2.26799402653369 1.04075901297853e-22 38.1717298906829 3.53196557910238 10.8075033676812 2.08913538435973e-23 4.44388994158904 14.8744528345251 0.298759893289945 0.765317780372398 ZNF234 other 1.53657660676151e-18 1 3.1360011254624e-19 10.8075033676812 0.298759893289945 0.930485009266286 6.91188074532636 19.7650885139623 0.349701482006707 0.72679349521868 -0.451615966378777 39.0990798452674 -0.0115505522934561 0.990791417794561 MYZAP other 1 1 1 0.349701482006707 -0.0115505522934561 0.0794855189583366 11.0119380758425 6.6179934268119 1.66393910746861 0.0971065699179184 -4.01327033154022 12.4172535677415 -0.323201125727689 0.746754688230939 TAPT1-AS1 other 1 1 1 1.66393910746861 -0.323201125727689 0.821804676623578 2.94109738423149 4.7359251267184 0.621018556150491 0.535098087073174 3.00567616260284 9.15454019084324 0.328326284001598 0.742913025861234 PPIAL4A other 1 1 1 0.621018556150491 0.328326284001598 0.0469046617995767 -5.3252976713184 2.62088329503409 -2.0318713471174 0.043013677466268 15.7992974808764 10.6502085490625 1.48347306140471 0.138958219689365 PPIAL4C other 1 1 1 -2.0318713471174 1.48347306140471 5.07767424699334e-26 181.194717797943 29.8851234038864 6.06304064230096 3.81803028389587e-09 -324.377737045352 69.9138066076353 -4.63968066945344 5.12465071129553e-06 SRSF8 other 7.59721620835144e-22 0.0759729467949563 5.00009245979004e-05 6.06304064230096 -4.63968066945344 0.0151548685736345 12.6700502871123 5.58112138552864 2.27016210755863 0.0238998659865354 37.4047687812172 21.4600403492257 1.74299620003122 0.0823487023887022 FAM72C other 1 1 1 2.27016210755863 1.74299620003122 0.377095536678181 25.1287638355991 37.7822513551188 0.665094401056507 0.506469165325067 -156.447954989237 128.309732898513 -1.21929920244616 0.223628630230394 IKBKE other 1 1 1 0.665094401056507 -1.21929920244616 0.725549189938309 -474.794033542199 594.572188695765 -0.798547329608019 0.425147042284087 -485.956562235043 1270.29409224401 -0.382554374772056 0.702304962877416 MSMB other 1 1 1 -0.798547329608019 -0.382554374772056 2.24894083690157e-26 261.55381422684 21.8185772503839 11.9876658878955 2.02611785384342e-27 257.857521073554 102.85530487858 2.50699291959664 0.0126927601925258 LINC00667 other 3.36823869142748e-22 1 3.0653137010797e-23 11.9876658878955 2.50699291959664 0.219422051100915 24.7950711980577 38.4810199573265 0.644345477992896 0.519818867392397 -113.415574649354 71.2122771763 -1.59264075165819 0.112240571709361 SNORD3A other 1 1 1 0.644345477992896 -1.59264075165819 0.00513959981683689 33.0280256450098 10.2530006577269 3.22130337718442 0.00141211346629608 21.0148461373406 41.7573310360105 0.503261238588691 0.615139160261824 NBPF11 other 1 1 1 3.22130337718442 0.503261238588691 0.182564238299151 -20.9549129205943 13.1499911196501 -1.59353057579493 0.112028434070418 -43.0694082600435 44.6577900380077 -0.96443214550894 0.335557564867057 C1orf186 other 1 1 1 -1.59353057579493 -0.96443214550894 6.99439505962987e-23 340.169842397976 31.302747325935 10.8670922349406 1.32801593935583e-23 -57.5396299998008 91.2672402616016 -0.630452173582476 0.528851574873018 KRT222 other 1.0336317019121e-18 1 1.99441433772458e-19 10.8670922349406 -0.630452173582476 1.94769906776148e-18 22.3211750947656 8.64922871368946 2.58071278187349 0.0103089750046077 -73.5062448443072 13.1465281975353 -5.59130469579703 4.86737988404687e-08 LINC00909 other 2.78852075531411e-14 0.000736969988243537 1 2.58071278187349 -5.59130469579703 0.000347969425052906 310.57183360612 86.5423685002106 3.58866805922194 0.000384925955810709 -271.720239623749 202.529838681441 -1.34163065251406 0.180676061990119 DYNLL2 other 1 1 1 3.58866805922194 -1.34163065251406 0.0883158939318056 64.2372377837687 31.601089026615 2.03275392596967 0.0429348449095223 56.178841050851 59.9036145486742 0.937820555138677 0.349071443100478 MYH4 other 1 1 1 2.03275392596967 0.937820555138677 3.56753176293191e-09 149.918119786801 23.4131598005855 6.40315621913843 5.52424954308353e-10 -74.365142526 96.9537394952857 -0.767016753692269 0.443646040091354 OTUD7B other 4.22467111366397e-05 1 7.39697013818885e-06 6.40315621913843 -0.767016753692269 0.556221864153079 -0.947566094705059 0.884299149977422 -1.07154473090837 0.284739686559788 -0.00175761592655284 2.07095069016152 -0.000848700036607711 0.999323369255636 SEPT4-AS1 other 1 1 1 -1.07154473090837 -0.000848700036607711 4.1025616115148e-12 86.5604338939448 13.0238849195253 6.64628368791667 1.30685666773654e-10 19.0839155046924 23.2670836248021 0.820210895891971 0.412710261477805 DSG2-AS1 other 5.33086855800233e-08 1 1.77209764145074e-06 6.64628368791667 0.820210895891971 0.227236123616138 13.7606114963003 17.6331019528994 0.780385183109407 0.435746504652386 -48.9294768779344 32.5938023327695 -1.50118959360385 0.134301907459357 SNORD3C other 1 1 1 0.780385183109407 -1.50118959360385 0.046359036341399 5.30195466144223 3.68575720313927 1.43849808037447 0.151270083516478 -9.96321048522813 7.70462732832839 -1.29314632111996 0.196893224692632 AGAP12P other 1 1 1 1.43849808037447 -1.29314632111996 0.0069871181397251 26.6571459753021 8.4028549275645 3.17239155085931 0.00166389001512518 2.47991905470105 34.2222542035488 0.0724650994627902 0.942278661191701 GJA5 other 1 1 1 3.17239155085931 0.0724650994627902 0.55926670933049 4.2572457154016 7.34130709601164 0.579902960021175 0.562393291648244 -14.0641172050451 17.2993398103826 -0.812985776289811 0.416838303507605 TSPOAP1-AS1 other 1 1 1 0.579902960021175 -0.812985776289811 0.230022380392732 7.43555608468085 15.142968500054 0.491023677732298 0.623750530338188 -45.4954891011353 28.0233026903569 -1.62348776672889 0.105482271638921 SNORD3B-1 other 1 1 1 0.491023677732298 -1.62348776672889 0.103762646151913 -8.8112611599088 4.17611496060781 -2.10991824770704 0.0356512754526342 -6.36591340377748 9.84075871584579 -0.646892540259824 0.518171095051289 MIR142 other 1 1 1 -2.10991824770704 -0.646892540259824 1.08431539634922e-07 312.714732888583 54.4091876280982 5.74746189974521 2.19006860832327e-08 -228.933497942733 209.92336416634 -1.09055749393064 0.276325639001922 RBM8A essential 0.0011941565459994 1 0.000279737463341131 5.74746189974521 -1.09055749393064 2.57006084446786e-11 197.55462120582 42.2200080883066 4.67917061485678 4.26761606453986e-06 -289.53715010395 90.1320402765506 -3.21236653708901 0.00145126414826508 TIMM23 essential 3.2740005097676e-07 1 0.0490605142779503 4.67917061485678 -3.21236653708901 0.0495098721309067 30.8448539118348 22.3645539134137 1.37918484899154 0.168803927119324 -123.463993132618 77.477646048606 -1.59354342096509 0.112028647488232 DTX2P1-UPK3BP1-PMS2P11 other 1 1 1 1.37918484899154 -1.59354342096509 0.597718119236394 -2.56791327226659 3.01297303457794 -0.852285514273214 0.394713601946098 4.225497561738 9.64931507109574 0.437906476325492 0.661759040471446 KRT18P55 other 1 1 1 -0.852285514273214 0.437906476325492 1.03340820020766e-06 127.015940974185 23.6709274137489 5.36590471315501 1.59293812212047e-07 -38.4501052095968 91.3279711065793 -0.421011271176995 0.674042397875668 RNF115 other 0.0106916412393485 1 0.00196807504987984 5.36590471315501 -0.421011271176995 1.09942366801912e-10 19.1776939191721 4.57422986232173 4.19255142316746 3.58261685304395e-05 -13.317244504872 7.2030024567899 -1.8488463088498 0.0654109827448279 MIR1539 other 1.37208073768786e-06 1 0.386779315454625 4.19255142316746 -1.8488463088498 0.881087340266462 -1.27176276715029 2.58926793818917 -0.491166923435396 0.623663955141283 -0.911759709150204 9.95602686094112 -0.0915786710788381 0.92709331236587 FCGR1CP other 1 1 1 -0.491166923435396 -0.0915786710788381 0.742219122449254 1.50478111230462 1.97966284248014 0.760119895173373 0.447749656793709 -0.453589670517575 5.72489325153297 -0.0792311141166023 0.936898946799156 RARA-AS1 other 1 1 1 0.760119895173373 -0.0792311141166023 1.69227233661731e-13 822.393110337273 236.288303319294 3.48046474914157 0.000570687373743821 -1322.87232527274 372.081264070038 -3.55533173265001 0.000435027576261275 RPL17 essential 2.26505893852447e-09 1 1 3.48046474914157 -3.55533173265001 7.95068537732881e-05 33.5031359262992 7.71181126421787 4.34439261782129 1.8809322942533e-05 29.6811505702154 17.2697315696624 1.71868048154009 0.0866458127552083 MAFG-AS1 other 0.692266175804019 1 0.207165882889059 4.34439261782129 1.71868048154009 0.0451922628033809 -12.557021885584 17.2858588780876 -0.726433206133708 0.468104260402431 -91.3875694503495 36.7755533740318 -2.48500868283006 0.0134654705771536 ZNF488 other 1 1 1 -0.726433206133708 -2.48500868283006 0.344713248202415 -0.29857046114456 0.816404417385194 -0.365713921662539 0.715543805442918 3.11933541749771 2.30239915604402 1.35481956258938 0.179288745674011 CYP4F35P other 1 1 1 -0.365713921662539 1.35481956258938 1.4052514623684e-06 69.6887591381757 34.6395367245669 2.01182711224747 0.0451349768733399 -238.525779911695 65.3167380907695 -3.65183239218437 0.000307308182024375 SEC22B other 0.0143925854775772 1 1 2.01182711224747 -3.65183239218437 0.188569492416332 8.6286249036058 4.83856042429297 1.78330415391405 0.0754845090923506 -6.0726380324323 24.5164125179989 -0.247696845041012 0.804527831336014 FSBP other 1 1 1 1.78330415391405 -0.247696845041012 0.725875564990687 -4.75533148324064 7.70278707018094 -0.617352062300864 0.537444328892132 -10.7568574356519 13.9834094065684 -0.76925856369471 0.442310815676949 DSCAS other 1 1 1 -0.617352062300864 -0.76925856369471 2.37905647047459e-16 122.688126082601 13.8128139888148 8.88219635636524 5.1058089202801e-17 158.082704350094 61.5815443761637 2.56704676622697 0.0107183771223501 LINC00668 other 3.33067905866443e-12 1 7.45856567074516e-13 8.88219635636524 2.56704676622697 0.540816273814361 -184.723240372123 515.640412629161 -0.358240424621203 0.720410403030606 -2062.88999705955 1989.46124428685 -1.03690886313245 0.300597022555843 TXNIP other 1 1 1 -0.358240424621203 -1.03690886313245 0.256183859860463 -72.9181254756992 62.0925289770589 -1.17434620037203 0.241129570828826 31.4978893373149 89.574100397222 0.351640588045378 0.725339253347379 ESRG other 1 1 1 -1.17434620037203 0.351640588045378 0.00558172838107635 112.536339664946 34.6871563619293 3.24432301370369 0.0013017070969212 23.3855546608134 117.798691400774 0.19852134503983 0.842763250235707 SRGAP2 other 1 1 1 3.24432301370369 0.19852134503983 4.95305338712667e-38 10.2212852510106 0.680703520720842 15.0157666882442 7.22344315768533e-39 4.0904967833229 2.87246045157551 1.4240393740075 0.155418661969687 NDUFV2-AS1 other 7.55637824740044e-34 1 1.10374211449432e-34 15.0157666882442 1.4240393740075 0.00390961015652689 84.2646397708528 29.6234328334553 2.84452650186066 0.00473694966179171 -72.6663316043287 68.1967853026244 -1.06553895879213 0.287443000485883 BAHCC1 other 1 1 1 2.84452650186066 -1.06553895879213 0.634055799152524 -5.5403107384776 57.4121897317223 -0.0965005996873931 0.923183405344831 -185.585603082122 194.973630881793 -0.951849756517269 0.341891570193801 RASSF5 other 1 1 1 -0.0965005996873931 -0.951849756517269 0.104072049965805 20.0858479863869 16.4676976504255 1.21971197266109 0.223475089027415 -60.5852524106636 37.9744460322276 -1.59542162535424 0.111608174977972 STRADA other 1 1 1 1.21971197266109 -1.59542162535424 0.000198811378012703 44.3709354082431 10.6421067601104 4.16937514426726 3.99120058875748e-05 -22.2089293601984 40.9200991515626 -0.542738894105302 0.587708576196412 NBPF15 other 1 1 0.429333447332642 4.16937514426726 -0.542738894105302 0.739912901788905 1.61009825793895 2.17859741291521 0.739052680588864 0.460420161201974 1.62688185313524 5.02447514813813 0.323791402120498 0.746308812269048 SNHG25 other 1 1 1 0.739052680588864 0.323791402120498 0.000173537687223762 -33.2984515592493 223.518601483124 -0.148973961622444 0.88166860777129 -1871.92885072765 477.171571101971 -3.92296809804627 0.000107206162443536 NCOA4 other 1 1 1 -0.148973961622444 -3.92296809804627 4.53727467799801e-10 374.941221633986 55.2565009799645 6.78546804420237 5.71703159941028e-11 20.798641451004 228.808571975311 0.0908997476425326 0.927629842653344 MRPS21 essential 5.56043011788656e-06 1 7.79860280475557e-07 6.78546804420237 0.0908997476425326 0.381066478250002 -1.99306017933953 5.60668139365748 -0.355479478750864 0.722464620729173 -16.4109920470024 11.9281785358677 -1.37581710381473 0.169840433814353 GDF10 other 1 1 1 -0.355479478750864 -1.37581710381473 0.662927009715481 -6.92737984025289 19.4710290196002 -0.35577882572511 0.722242102592991 36.9216729955549 47.9851318990054 0.769439856355177 0.442203375810553 MYO15B other 1 1 1 -0.35577882572511 0.769439856355177 0.765830007513567 56.5229135317967 90.2191250774182 0.626507001517624 0.531433337359729 6.90512033934641 164.416003627838 0.0419978602264074 0.966526843704362 DSG1-AS1 other 1 1 1 0.626507001517624 0.0419978602264074 9.38368392367216e-12 21.7769321477911 5.25770890981141 4.14190525214378 4.41535457190169e-05 -32.9126956341614 7.85112897551043 -4.19209717950426 3.58374476495778e-05 MIR3661 other 1.20730477361966e-07 0.519678828366527 0.473458470745018 4.14190525214378 -4.19209717950426 0.404518924606212 1.49391993008902 2.72264899193413 0.548700891857443 0.583594554755681 -2.76393904637063 3.82404342023325 -0.722779200609089 0.470345116060514 MIR4444-2 other 1 1 1 0.548700891857443 -0.722779200609089 0.351825126070871 23.1731615494402 22.7906637855041 1.01678309010812 0.310027167065431 -54.0624058980982 73.7224721352554 -0.733323291152151 0.463899830983071 FXYD1 other 1 1 1 1.01678309010812 -0.733323291152151 0.00723108317518802 83.5579434910262 26.9222031235372 3.10368148949794 0.00208186853852066 -23.7807049153955 65.931397257009 -0.360688623398884 0.718570209464658 AARSD1 other 1 1 1 3.10368148949794 -0.360688623398884 0.171519534241724 1.13216473081423 10.5946607122259 0.106861820455255 0.914965775035375 25.0487883447703 16.1246502281177 1.55344692693494 0.121307915306889 LINC01929 other 1 1 1 0.106861820455255 1.55344692693494 0.304199360905677 4.60113262300673 3.81237127008875 1.206895209579 0.22836950335481 -6.37685337639738 10.9663346147928 -0.581493598398451 0.561319780591466 ZNF850 other 1 1 1 1.206895209579 -0.581493598398451 0.0773780892296097 8.86232942652825 5.31117336939701 1.66861987175809 0.0961708142954626 21.748234922211 13.0068508773866 1.67205998801923 0.0954899405378795 PTGES3L other 1 1 1 1.66861987175809 1.67205998801923 0.901020908099592 0.757541282265034 7.54980731161763 0.100339154497272 0.920137907342685 -7.94269258933612 18.2012873648447 -0.43638081362735 0.662854728816975 ASB16-AS1 other 1 1 1 0.100339154497272 -0.43638081362735 5.41518485441433e-09 135.084103262105 24.3834133541814 5.53999972440035 6.33554058501428e-08 -66.4352858393697 54.1758941512996 -1.22628868208124 0.220994479276748 ILF3-AS1 other 6.36609131484948e-05 1 0.000795046988013442 5.53999972440035 -1.22628868208124 0.390444823623543 7.21225385461973 6.33807498495899 1.13792498065032 0.25602487687728 -9.35876497343297 14.5662511579896 -0.642496471598987 0.521022714308646 TBC1D3P1-DHX40P1 other 1 1 1 1.13792498065032 -0.642496471598987 0.0373460302245799 12.5854002986819 4.95996340950095 2.53739781115607 0.011642342461124 4.84632761941864 10.912094409441 0.444124421726562 0.657252813706624 ZNF561-AS1 other 1 1 1 2.53739781115607 0.444124421726562 0.401056455703293 1.76053795001319 5.51360268987663 0.319308091104509 0.749702551434049 -16.9486170302824 14.3907454422005 -1.17774420361721 0.239779247907369 PCAT19 other 1 1 1 0.319308091104509 -1.17774420361721 0.0188104915500274 7.62043788027382 3.21631521097649 2.36930691813636 0.0184146160609702 -7.83695567176053 7.57178849710422 -1.03502041489375 0.301440906799284 LINC02081 other 1 1 1 2.36930691813636 -1.03502041489375 9.44132434688514e-47 301.121068235293 17.3905631798973 17.3151993480795 1.52483547767219e-47 108.420605907689 74.3499883581937 1.45824644094568 0.145778508897004 CHMP1B-AS1 other 1.44546675750812e-42 1 2.3360479517938e-43 17.3151993480795 1.45824644094568 1.18827249767074e-07 7.99887772886167 3.03229164925743 2.63789854475921 0.00876306121717914 -10.3173331452807 4.48027374766748 -2.30283543514548 0.0219500377079207 PARD6G-AS1 other 0.00130519851144154 1 1 2.63789854475921 -2.30283543514548 0.783883085494178 1.84267914874588 3.55126031907967 0.518880336326181 0.604202833440001 4.55541460950773 7.54639350766723 0.603654527805815 0.546501012204455 LINC01140 other 1 1 1 0.518880336326181 0.603654527805815 0.198648037985291 -1.6197753466046 9.38215309118419 -0.17264430998537 0.863040162403001 -41.0683113156572 22.7859961963913 -1.80234873040843 0.0724314315603495 MAP3K14-AS1 other 1 1 1 -0.17264430998537 -1.80234873040843 0.00216050619578833 10.9270228251311 3.22146021765268 3.39194715652676 0.000781061144148838 -1.11058096679386 9.59327678985479 -0.115766592700456 0.907910140380043 CEBPA-AS1 other 1 1 1 3.39194715652676 -0.115766592700456 0.302453162290428 6.24180554524759 4.06890377152614 1.53402633626463 0.126011234949794 2.05419830175213 10.7596857838006 0.190916198021772 0.848712317916421 LINC01764 other 1 1 1 1.53402633626463 0.190916198021772 0.299192634096308 2.05603143481626 1.79553645646449 1.14507919202303 0.253037421293131 5.0992721636525 4.23146382060286 1.20508466569519 0.229066635917057 KCNJ2-AS1 other 1 1 1 1.14507919202303 1.20508466569519 0.0208240284996707 14.9179898043882 9.090479553151 1.64105641700907 0.101768164465159 -39.4724002436686 21.8077926926304 -1.81001354882687 0.0712316788744049 DM1-AS other 1 1 1 1.64105641700907 -1.81001354882687 3.65243684997053e-26 13.705761982405 1.16300185025556 11.7848152858856 7.63832120621003e-27 0.910499868110556 4.82692835568673 0.188629248461472 0.850503729054977 ZNF285 other 5.4662369896659e-22 1 1.15483778316689e-22 11.7848152858856 0.188629248461472 1.10314286415803e-05 58.7981448428795 12.8825573377034 4.56416713712539 7.16663636737851e-06 -3.05693114825032 27.7176041951513 -0.110288433543079 0.912249981597946 S1PR2 other 0.104820634952296 1 0.0812768230424397 4.56416713712539 -0.110288433543079 6.78867207409153e-17 74.645085743389 8.46789807539076 8.81506662914628 7.89359686014033e-17 -34.7177472843971 35.661545309277 -0.973534572977847 0.33102531554314 ZNF224 other 9.55234047545419e-13 1 1.15159684592587e-12 8.81506662914628 -0.973534572977847 8.67849783171023e-12 61.9040666394569 12.8059788549574 4.833997255547 2.08380903998777e-06 -77.6843023759167 28.15114958645 -2.75954280791818 0.00612266355309876 LUZP6 other 1.11813766063755e-07 1 0.0243993200492169 4.833997255547 -2.75954280791818 0.257429307022314 0.138731747111779 1.5400541877943 0.0900823803547287 0.928278107558309 -5.83410578214449 3.69454463501807 -1.57911362792778 0.115297946580141 EML2-AS1 other 1 1 1 0.0900823803547287 -1.57911362792778 0.631662899306795 0.341539318161777 33.3330626574585 0.0102462627473373 0.991831213012679 -90.7482362586474 98.460904446344 -0.921667709320104 0.357398442639381 SMIM22 other 1 1 1 0.0102462627473373 -0.921667709320104 1.46200078447172e-35 87.9055404639043 6.38064517710975 13.7769046897109 3.48487715835794e-34 -51.429475092508 30.1225582468616 -1.70734087958371 0.0887347732923652 LIN37 other 2.22487279380906e-31 1 5.31060430162166e-30 13.7769046897109 -1.70734087958371 0.0267947675538736 10.2031461033667 4.23313809883164 2.41030315221296 0.0165231241209427 -4.59740121893812 10.7486886852694 -0.427717403820493 0.669154805548185 MZF1-AS1 other 1 1 1 2.41030315221296 -0.427717403820493 0.121419870238283 -4.80016833207979 2.66813225735947 -1.79907435954105 0.072957920484348 -11.9038644747681 8.53252958873581 -1.39511552242174 0.163957655208334 CCDC177 other 1 1 1 -1.79907435954105 -1.39511552242174 0.0614205379834372 -1.29986328125 2.80048303534154 -0.464156813251852 0.642851003915125 -15.2166220238096 6.41627259513197 -2.37156726092879 0.0183043504660021 CARD8-AS1 other 1 1 1 -0.464156813251852 -2.37156726092879 1.71936955502828e-05 19.9427734374999 11.2787409497966 1.76817372845678 0.077987633190279 -102.426600609756 26.1002121560634 -3.92435892847566 0.000106551284981177 PTOV1-AS1 other 0.160709472308493 1 1 1.76817372845678 -3.92435892847566 0.0074749284771394 32.6219328941566 11.3365149275156 2.87759801868013 0.00428718650671672 55.3954478436463 45.8187737077053 1.20901201322048 0.227585510148957 NBPF12 other 1 1 1 2.87759801868013 1.20901201322048 8.29807531205963e-08 17.0915035154063 5.7775572141917 2.958257769118 0.00332434641464103 -54.7901970280286 13.0844817389432 -4.18741820434179 3.65160386190458e-05 NAPA-AS1 other 0.00091975866758869 0.529299979783069 1 2.958257769118 -4.18741820434179 0.00240585480551348 -4.30880694677212 4.07810231892212 -1.05657156437187 0.291504154238461 26.0931554240242 10.4130670711634 2.5058088309335 0.0127132931029068 FENDRR other 1 1 1 -1.05657156437187 2.5058088309335 0.0217628251635907 12.5457824877976 6.84315602641793 1.8333328130127 0.0676996073764555 -24.9451979805901 17.4721480264431 -1.42771214751827 0.154368497083948 A1BG-AS1 other 1 1 1 1.8333328130127 -1.42771214751827 2.8723339158009e-17 28.7508938325553 3.11157328921781 9.23998606498603 3.6344306329889e-18 13.119831345534 6.55554272333027 2.00133412277862 0.0462057767587372 MAN1B1-AS1 other 4.06090569015931e-13 1 5.34552057500008e-14 9.23998606498603 2.00133412277862 0.762530627338902 2.05596718317295 67.8091017875528 0.0303199294633682 0.97583080357381 64.3352318732876 93.8538284769178 0.685483297989384 0.493535271645003 MTRNR2L2 other 1 1 1 0.0303199294633682 0.685483297989384 0.831146181913768 -0.878428459272146 5.0795308735253 -0.17293495819674 0.862811883770606 -7.65725115442735 12.65953424433 -0.604860416397774 0.545700405598031 TRABD2B other 1 1 1 -0.17293495819674 -0.604860416397774 2.97262608276254e-09 90.236022362103 15.6087478167543 5.78111860230354 1.76743194878286e-08 -63.7265459974271 48.9519406334382 -1.30181858314105 0.193917681667624 FBXO17 other 3.53118252371362e-05 1 0.000226673147431402 5.78111860230354 -1.30181858314105 0.0405419222146188 17.7490267058261 9.97653687548264 1.77907694096179 0.0761763020058952 -22.0242035131729 22.5751987133466 -0.975592897003032 0.330003164062311 ZSCAN16-AS1 other 1 1 1 1.77907694096179 -0.975592897003032 0.000229991034924098 23.5742743327831 6.79577121275481 3.46896232888728 0.000594272421133239 -21.8105688977201 17.8637374280014 -1.22094096969496 0.223010020753429 ZNF587B other 1 1 1 3.46896232888728 -1.22094096969496 9.17649064907347e-12 10.6772772454067 5.80560711574153 1.83913189999645 0.0668221462083918 -62.8060641123209 10.8274891626119 -5.80061205040913 1.58714819283796e-08 RAB11B-AS1 other 1.18101434653576e-07 0.000240960838636659 1 1.83913189999645 -5.80061205040913 0.280469456840088 -218.485202112912 227.516972199276 -0.960302873235966 0.337627830110046 -787.514309931441 540.920034296816 -1.45587935369262 0.146406346096533 SPIB other 1 1 1 -0.960302873235966 -1.45587935369262 0.00753363890537212 5.1021838717321 2.02727696923287 2.51676704720954 0.0123322446808967 -5.93859376939309 4.61911975243012 -1.2856548623293 0.199493133934165 PLA2G4C-AS1 other 1 1 1 2.51676704720954 -1.2856548623293 0.0337959136803511 -18.0922993390162 14.9287497258867 -1.21190988336041 0.226440962122625 -71.7447561828998 27.4273082072807 -2.61581470703183 0.00932339184616302 RPARP-AS1 other 1 1 1 -1.21190988336041 -2.61581470703183 0.227080858046373 14.2463929664053 8.36868638261278 1.70234518478364 0.0896618137151631 18.4928197110515 15.5062211643263 1.19260647162677 0.233907099968646 KCNQ1OT1 other 1 1 1 1.70234518478364 1.19260647162677 0.459298952689597 5.20464209780299 4.44728174732431 1.17029736218856 0.242760384436226 7.78832690878297 11.3781572576625 0.684498089841219 0.49416082243855 ZNF528-AS1 other 1 1 1 1.17029736218856 0.684498089841219 0.310045729619595 2.86914081202719 1.89052959112645 1.51763866881219 0.130114858261223 3.25550832495453 4.82546579276694 0.674651622198695 0.500395130837458 RNF225 other 1 1 1 1.51763866881219 0.674651622198695 1.1558889167897e-08 243.146416622645 59.0261089514802 4.11930281263351 4.84718872539788e-05 -578.033808769149 171.726992994148 -3.36600436944032 0.000855845308805431 EGLN2 other 0.000133713229894232 1 0.517922115308763 4.11930281263351 -3.36600436944032 0.507944155300859 3.02787239014561 6.38274821846147 0.474383805613354 0.63554978633806 -8.474939870921 11.6898830357699 -0.724980724356991 0.468993640976005 ARHGAP19-SLIT1 other 1 1 1 0.474383805613354 -0.724980724356991 0.0948968529762671 21.4476473873423 50.9731571932406 0.420763565930077 0.674211949729963 -171.381727635061 92.7222475994174 -1.84833448360173 0.0654822365466365 SNHG8 other 1 1 1 0.420763565930077 -1.84833448360173 9.86402873018237e-08 71.7317918881729 29.2181993422078 2.45503807568836 0.0146187332622699 -186.982000672012 58.1416687702487 -3.21597237621241 0.00143286578446652 COMMD3-BMI1 other 0.00108889013152483 1 1 2.45503807568836 -3.21597237621241 0.173286456287331 1.57708873392754 1.25355784995453 1.25809011046817 0.209312085844938 -4.34786488826858 3.94815609942711 -1.10123935801309 0.271652353489093 RMRP other 1 1 1 1.25809011046817 -1.10123935801309 9.0378066694259e-11 117.979635762844 49.4376520045752 2.38643282961589 0.0175935304960912 -521.990655583364 108.789410545932 -4.79817523565839 2.45994879226962e-06 C7orf55-LUC7L2 other 1.13171415114551e-06 0.0366581569024019 1 2.38643282961589 -4.79817523565839 0.40979843010665 1.60952553827249 1.71074838608321 0.940831247520583 0.347501012372457 -3.32140430245656 4.34141369976702 -0.765051324787315 0.444804828323027 MKNK1-AS1 other 1 1 1 0.940831247520583 -0.765051324787315 0.268041171989888 12.6928368574068 8.60690646085581 1.47472694343011 0.141281548943366 -19.4461426641772 40.699594072591 -0.477796968429056 0.633125054925361 C8orf44-SGK3 other 1 1 1 1.47472694343011 -0.477796968429056 0.0163448833097477 7.89504825378224 3.27688611926648 2.40931419842857 0.0165504755962257 16.0678979256124 10.5494423899539 1.52310400224694 0.128726484003277 GAS5-AS1 other 1 1 1 2.40931419842857 1.52310400224694 0.0150498580548929 28.7063583245797 10.2564124473496 2.79886933876161 0.00543931580527616 -31.5640795380653 34.6042572963047 -0.91214440084041 0.362379357274263 TSNAX-DISC1 other 1 1 1 2.79886933876161 -0.91214440084041 3.0273397744991e-19 157.604961027482 19.5649825428196 8.05546136739707 1.63603269275677e-14 -169.484881677112 45.3948932372614 -3.73356713917754 0.000223868036650655 BIVM-ERCC5 other 4.3660294227826e-15 1 2.34639808795176e-10 8.05546136739707 -3.73356713917754 0.578495376757907 5.71739650585178 16.547534977779 0.345513486663085 0.729964155107856 -24.3212250173317 31.9139948311445 -0.762086512391013 0.446640802078099 NBPF8 other 1 1 1 0.345513486663085 -0.762086512391013 0.00579473934107143 39.4173025746386 12.4718263780273 3.16050764177439 0.00172848290354874 32.5765014681022 51.6476209847746 0.630745440873367 0.528665787047763 HIST2H4B other 1 1 1 3.16050764177439 0.630745440873367 0.545881827871196 -1.53713056958543 1.72929693669727 -0.888876014850955 0.374737398596341 2.05138417821497 4.18420814687053 0.490268195608112 0.624280106613462 POC1B-AS1 other 1 1 1 -0.888876014850955 0.490268195608112 0.719317955081513 5.08474178065737 9.83417453520553 0.517048153096573 0.605480844922597 -9.83179042637293 21.2033513723927 -0.463690397508299 0.643185808430877 HMGN3-AS1 other 1 1 1 0.517048153096573 -0.463690397508299 0.135507906192518 -0.283797201306614 1.25760611999716 -0.225664615330637 0.821610028866301 9.18095860987175 4.73122118572061 1.94050505133452 0.053218962849385 LINC01235 other 1 1 1 -0.225664615330637 1.94050505133452 0.00138856791000965 194.053150768476 54.0825622319156 3.58809092543253 0.000385228381276201 -11.6206158124801 216.886154987448 -0.0535793343431838 0.95730375489174 URGCP-MRPS24 other 1 1 1 3.58809092543253 -0.0535793343431838 0.000552641616532417 295.134621271769 111.812155390731 2.63955757082415 0.00870927657893465 -701.420435611172 275.291026883649 -2.54792335061333 0.0113052695888265 TAF15 other 1 1 1 2.63955757082415 -2.54792335061333 0.00114754828252676 5.58009183279886 1.5476051826669 3.6056301021059 0.000362067240003645 -3.08893808990802 7.30453163972305 -0.422879691985993 0.672672497545431 YTHDF3-AS1 other 1 1 1 3.6056301021059 -0.422879691985993 6.2854298757606e-11 319.052793755136 51.7532059617715 6.1648894561394 2.15758541455118e-09 -254.547746214344 126.40553805875 -2.01373887666249 0.0448869879610916 HSPE1-MOB4 other 7.92152727242108e-07 1 2.84563940325155e-05 6.1648894561394 -2.01373887666249 7.01984494753076e-05 320.968585808565 101.7485013192 3.15452887902142 0.00176066638032585 -404.068865415048 235.573114518872 -1.71525883265715 0.0872688438268998 RPS10-NUDT3 other 0.615710600347923 1 1 3.15452887902142 -1.71525883265715 0.940988851291676 0.712791920267738 3.59284527961804 0.198392044408747 0.842865112371488 -2.93726374469803 13.3458502156874 -0.220088169522945 0.825943708493455 LINC00221 other 1 1 1 0.198392044408747 -0.220088169522945 0.00568918388246392 39.5902585383878 12.5194564117991 3.1622985244851 0.00171871825337038 32.720326939121 51.0937027672127 0.640398428123277 0.522382134449971 HIST2H4A other 1 1 1 3.1622985244851 0.640398428123277 4.50758043553993e-05 32.574304941478 7.55623758574706 4.31091592499967 2.17108828953506e-05 35.9219839020756 18.3895845612009 1.95338746139296 0.0516503519569824 RASL10B other 0.404284889263577 1 0.237994698298833 4.31091592499967 1.95338746139296 0.000692414052881146 30.7576803406776 8.41674835170282 3.65434239630735 0.000301373021495251 -24.2177440850733 33.3231287578869 -0.726754809280669 0.467909128498168 GPR75-ASB3 other 1 1 1 3.65434239630735 -0.726754809280669 4.21058733462699e-12 19.0767781983942 2.62826556668726 7.25831454788611 3.00718052495702e-12 27.5934242718112 16.2998133787567 1.69286749673916 0.0914570000627486 LPP-AS2 other 5.46828977148007e-08 1 4.19411467815755e-08 7.25831454788611 1.69286749673916 0.000136670415855226 10.0721732175755 5.98130370746008 1.6839427840812 0.0931739935533984 -35.468160748007 13.7899340657129 -2.57203265650083 0.0105640718289387 CTAGE15 other 1 1 1 1.6839427840812 -2.57203265650083 0.00793356739869397 3.05279723311891 6.66364629836499 0.458127141872453 0.647173017320101 -39.0851132207333 14.0972959944883 -2.7725255422043 0.00588928138626235 TMEM56-RWDD3 other 1 1 1 0.458127141872453 -2.7725255422043 0.000661830972126517 918.712083153233 245.363278784184 3.74429330951887 0.000214570605970678 52.4292978848771 924.382213012868 0.0567182028676132 0.954805182440349 SRXN1 other 1 1 1 3.74429330951887 0.0567182028676132 7.50425310946924e-05 9.20485381101714 5.01458761912995 1.83561531079882 0.0673482287157786 -29.7904855038608 11.5611639228911 -2.57677217471811 0.010423307054413 CTAGE6 other 0.655871721767612 1 1 1.83561531079882 -2.57677217471811 0.232598879358456 35.7797155024627 22.0064376004922 1.62587494405103 0.10500229813279 -51.8434569464767 88.7318928246448 -0.584270833136983 0.559467193014919 NBPF10 other 1 1 1 1.62587494405103 -0.584270833136983 0.727798016655426 -77.9501866022391 104.076660423693 -0.748968945437969 0.454429558903853 -91.9806870165226 253.290943540346 -0.363142423218425 0.71673976429053 MMP28 other 1 1 1 -0.748968945437969 -0.363142423218425 0.752539074778569 -109.850265650937 202.053058839373 -0.543670391737373 0.587049242648804 -290.184963504707 499.369214658755 -0.581103029555006 0.561582643213994 CCL5 other 1 1 1 -0.543670391737373 -0.581103029555006 0.333025003617612 -0.566248173694404 0.540730163968612 -1.04719176296456 0.295845759001805 2.26997893377734 2.07916838485152 1.09177253286267 0.275800444660893 PPIAL4E other 1 1 1 -1.04719176296456 1.09177253286267 8.13737784218951e-08 134.112483551225 23.2804376742413 5.76073720897501 2.04019058367626e-08 -119.671608424276 89.8213704135093 -1.33232890873682 0.183743476405819 LIX1L other 0.000902272455141972 1 0.000261083188993051 5.76073720897501 -1.33232890873682 0.0195900682660895 -7.73163241087956 3.11753009984258 -2.48005060521147 0.0136537518631459 -11.7145250866284 7.18992523234087 -1.62929720519701 0.104240274042926 MILR1 other 1 1 1 -2.48005060521147 -1.62929720519701 0.748602629241662 1.20844126618997 3.19034549822136 0.378780689070725 0.705101916214164 -4.52871871957263 7.71936232679884 -0.586670054837374 0.557838955825358 ATP2B1-AS1 other 1 1 1 0.378780689070725 -0.586670054837374 1.78227030306995e-11 119.549771225216 23.415295203165 5.1056273340964 5.67957240220737e-07 -218.26534669879 56.1090510078182 -3.89002028689413 0.000122017789074533 MROH7-TTC4 other 2.27827612841432e-07 1 0.00684786044534142 5.1056273340964 -3.89002028689413 0.0141837553666339 3.18800821281524 1.93842291862278 1.6446401774285 0.101029070058275 -7.54392593338082 4.57109395872055 -1.65035459815671 0.099854618649696 BMS1P4 other 1 1 1 1.6446401774285 -1.65035459815671 0.159269674767219 -0.878861047597803 1.98524358763016 -0.44269683230506 0.658286954319337 13.8616645289016 8.01898825166265 1.72860516736978 0.0848534707825885 LINC01215 other 1 1 1 -0.44269683230506 1.72860516736978 2.03651634672745e-12 21.9343766900983 4.04412964017415 5.4237570606549 1.15972179836128e-07 -5.93426878859716 6.3586515497471 -0.933259000303795 0.351396547024832 SNORD58B other 2.66355972988483e-08 1 0.00143991058484537 5.4237570606549 -0.933259000303795 5.93926748392016e-05 6.32474104258646 1.4283443568536 4.4280225648938 1.32516143303393e-05 -4.72307145285175 5.51088640816002 -0.85704387698107 0.392091332562992 ANKRD34A other 0.525031245578542 1 0.147463964268016 4.4280225648938 -0.85704387698107 1.27091563662985e-05 94.0295464156357 24.1191785750918 3.89853850631303 0.000117923086214184 -101.3014576685 52.7446796371968 -1.92060049213116 0.0556705382868054 GTF2H5 other 0.120241328381551 1 1 3.89853850631303 -1.92060049213116 0.0297807521775214 2.02566157556107 1.47963766788528 1.3690254171862 0.171963626605516 8.72485972133683 3.43307201100128 2.54141471352131 0.0115181076831112 FGF14-AS2 other 1 1 1 1.3690254171862 2.54141471352131 0.0132861684210524 12.1801459345588 4.12047347748215 2.95600639128531 0.00336129506309282 0.942386429275336 15.8436846247353 0.0594802567455852 0.952608800339994 NBPF25P other 1 1 1 2.95600639128531 0.0594802567455852 0.0191258122970891 19.9973029481677 10.3290291342391 1.93602929067939 0.0537501047032569 -25.0637850841918 22.5308482933837 -1.11242083555069 0.266797491313966 CASC15 other 1 1 1 1.93602929067939 -1.11242083555069 0.0726599332001926 100.838878418494 44.6199008348537 2.25995299253839 0.0245090424943826 -87.0332502891716 184.777406038687 -0.471016733890881 0.637955841191225 HIST2H2AA4 other 1 1 1 2.25995299253839 -0.471016733890881 1.42533120299115e-08 437.320551361503 75.6343365244911 5.782037252616 1.75871705149578e-08 22.6009877854402 175.112320954458 0.129065662897119 0.897387028142652 NUDT3 other 0.00016416964796052 1 0.000225573049024849 5.782037252616 0.129065662897119 6.08651789739768e-25 350.92111504852 32.6369841487709 10.7522531324861 3.31706004839761e-23 -334.077846290743 154.076810218206 -2.16825520866908 0.0308804948677344 KMT2B other 9.07073762249176e-21 1 4.97691689661578e-19 10.7522531324861 -2.16825520866908 7.97494977917085e-16 454.229467904738 54.3886467494683 8.35154935913494 2.12573140435981e-15 -85.877319151899 188.255177298306 -0.456175072496514 0.648576453703786 POM121C other 1.10947501327825e-11 1 3.07316989128297e-11 8.35154935913494 -0.456175072496514 0.0142792371755665 -247.914167016045 844.216911808695 -0.293661692330826 0.769207393864797 -5538.25347156052 1915.22533069933 -2.89169811133308 0.00409477572202593 CD24 other 1 1 1 -0.293661692330826 -2.89169811133308 0.000888134586610968 79.6745167414366 24.4613653503576 3.25715738268354 0.00124724787141615 -33.1212527008868 50.1571322020637 -0.660349809623366 0.509508917273801 FAM47E-STBD1 other 1 1 1 3.25715738268354 -0.660349809623366 0.980602959054886 -0.283523443685306 2.21731970264944 -0.12786764278806 0.898334035851345 -0.591322721985712 3.13967899003018 -0.188338592532362 0.850730613828774 LINC01023 other 1 1 1 -0.12786764278806 -0.188338592532362 0.583359267086595 11.2114457612987 79.5784424751327 0.140885463607838 0.888049069942633 108.379792430183 114.799115338912 0.944082122150702 0.34583993165893 MUSTN1 other 1 1 1 0.140885463607838 0.944082122150702 0.000192152888631223 23.8607298154836 12.3622273164855 1.93013194181152 0.054474025049535 -78.9753659239143 29.0366606047048 -2.71985015766992 0.00688787759726606 ZSWIM8-AS1 other 1 1 1 1.93013194181152 -2.71985015766992 0.000284478515294887 31.4971160017904 8.3516478111157 3.77136544956661 0.000193777472698002 11.1503039116988 15.4537333206694 0.721528169299078 0.47111813186805 ZNF595 other 1 1 1 3.77136544956661 0.721528169299078 0.0327487469684399 252.479033633049 98.0861509869265 2.57405384035001 0.0105024050710674 186.259854270562 181.994679443445 1.02343571163817 0.30687735483682 AFAP1-AS1 other 1 1 1 2.57405384035001 1.02343571163817 0.698305788316627 -477.728813559322 574.974826992871 -0.830869093970344 0.411844475848056 258.497175141242 1036.84588192066 0.249311088223065 0.804620195858152 DOC2B other 1 1 1 -0.830869093970344 0.249311088223065 0.16677595038272 25.1897897235563 13.8119828525287 1.82376346629655 0.0691263392603836 23.7671492176142 21.8402455003181 1.08822720043454 0.277318881445391 PCDHB16 other 1 1 1 1.82376346629655 1.08822720043454 0.00338210915180807 9.25031761651232 2.74110156442031 3.37467160523422 0.000831753694647826 2.32529641030336 6.72138423347998 0.345954989259621 0.729608220291915 GAS6-AS2 other 1 1 1 3.37467160523422 0.345954989259621 0.000533076889277439 155.910390972384 39.7138109530651 3.92584814276937 0.000105859187994381 122.571282694698 171.896434791735 0.713053082474932 0.476332562497622 STAG3L5P-PVRIG2P-PILRB other 1 1 1 3.92584814276937 0.713053082474932 1.08549126218876e-05 4.02321747840003 1.26283727885721 3.18585580720329 0.00158690818877445 -5.76029074502242 2.59636929581905 -2.21859454057566 0.0272223919226994 JMJD1C-AS1 other 0.103197654296286 1 1 3.18585580720329 -2.21859454057566 1.21349737494281e-12 130.980428400566 28.2530318383962 4.63597780053331 5.18145717250055e-06 -111.477348751831 40.7575589545312 -2.7351331044186 0.00658313668077181 DCP1A other 1.59550634857481e-08 1 0.0593069587964413 4.63597780053331 -2.7351331044186 0.0039139838030314 2.08670179760505 1.12574687386477 1.85361544948489 0.0647172613143531 -8.56858960704595 3.55485112954632 -2.41039337367118 0.0165007050405619 TBC1D8-AS1 other 1 1 1 1.85361544948489 -2.41039337367118 1.40780410953025e-21 20.1804444326747 1.95004982352633 10.3486814486523 7.98742847190311e-22 -5.03991320553602 8.78320101024152 -0.57381280465508 0.56650009226773 RBAK-RBAKDN other 2.06468550703706e-17 1 1.19412055654952e-17 10.3486814486523 -0.57381280465508 0.0142106429905113 5.11842319896835 1.74456156669863 2.93393096390078 0.00359112202301464 -1.1087764546804 11.0485874840632 -0.100354588881133 0.920126258589085 LINC02012 other 1 1 1 2.93393096390078 -0.100354588881133 6.7470575211311e-21 242.727817200113 25.9662223742988 9.34782941088739 1.7084329333921e-18 -236.468575807996 108.550127927712 -2.17842742631746 0.0301153855096958 ARL2-SNX15 other 9.85340280385986e-17 1 2.51823014381995e-14 9.34782941088739 -2.17842742631746 4.29353958636885e-07 69.8611362795989 12.7619813382217 5.47416066738532 8.8944874106414e-08 7.13314224100212 50.2424465112871 0.141974420759937 0.887189552626305 LINC02035 other 0.00456145645655826 1 0.00110985413909983 5.47416066738532 0.141974420759937 0.0148205013289346 7.22578653096028 3.32157749045076 2.17540808598739 0.0303597750287598 -10.2067795177518 8.50441260327424 -1.20017454395641 0.230993866426613 FAM95C other 1 1 1 2.17540808598739 -1.20017454395641 0.165237944086744 -1.37057995103773 2.79992504689822 -0.489505943223755 0.624822098452398 -16.7100479845366 8.80622000345596 -1.89752788119974 0.0586667654945658 C2orf15 other 1 1 1 -0.489505943223755 -1.89752788119974 6.65395837726081e-09 97.7017060891969 15.7252338256427 6.21305267524081 1.62673563404133e-09 -57.4819580127425 103.805425384966 -0.553747145677294 0.580141049614916 C1QTNF3-AMACR other 7.7864620930706e-05 1 2.15249659096349e-05 6.21305267524081 -0.553747145677294 0.000221016610979639 25.136976457774 10.0272089341698 2.50687670146321 0.0126788446048185 -36.3692515869103 22.3967013002723 -1.62386643904869 0.105395101085096 PAXIP1-AS1 other 1 1 1 2.50687670146321 -1.62386643904869 0.180718281917454 36.9305144083749 21.153760542412 1.74581320112476 0.0818031243289834 -2.96921556768911 43.304531635672 -0.0685659319137683 0.945377961066123 AGBL1 other 1 1 1 1.74581320112476 -0.0685659319137683 0.33317257863883 3.19243126968154 2.9501114978515 1.08213919101245 0.280005458781416 -3.49635789574681 6.70977628785673 -0.521084123486275 0.602668572799619 HIST1H4K other 1 1 1 1.08213919101245 -0.521084123486275 3.46126643023296e-06 58.6712681120308 13.288514204191 4.41518646934408 1.38466430769986e-05 -72.9670138481446 32.574082200498 -2.24003283957542 0.0257793263386734 CWC25 other 0.0343565305864924 1 0.153850051228531 4.41518646934408 -2.24003283957542 0.0682767566638173 14.3719434758465 7.4246685697455 1.93570168699653 0.0540788013150144 -6.39435067355681 13.9303555567632 -0.459022790014311 0.646633247628677 SMIM11B other 1 1 1 1.93570168699653 -0.459022790014311 5.4652347387298e-05 92.9153068073545 21.935814098204 4.23578110168986 2.98607428462696e-05 98.7481627857132 53.7711741576333 1.83645167383229 0.0672241923834731 EPOP other 0.485531454188755 1 0.324138363596256 4.23578110168986 1.83645167383229 0.00292986637048218 54.6473133368082 22.1514256646857 2.46698854349264 0.0141504401364667 -118.734688762901 54.9573884961943 -2.16048636974669 0.0314792888865265 ZNHIT3 essential 1 1 1 2.46698854349264 -2.16048636974669 0.00415218991964837 20.6351216786747 6.50905994525228 3.1702153386567 0.00167108821739454 -11.9185168538819 16.2643199632395 -0.732801425501964 0.464217665033949 LHX1 other 1 1 1 3.1702153386567 -0.732801425501964 2.579878598181e-05 400.889552489906 140.845019699777 2.84631684772692 0.00471480765216036 -716.24937378496 307.113018863777 -2.3322012737684 0.0203239934517023 CYFIP1 other 0.237194038316761 1 1 2.84631684772692 -2.3322012737684 0.000878639677525319 48.9021833583073 15.7072497633863 3.11335110187773 0.0020173388613869 -26.9470410739579 34.1631003746319 -0.788776216984323 0.430828617624056 HIST1H2BG other 1 1 1 3.11335110187773 -0.788776216984323 1.22263698081788e-11 207.461414114664 40.8502467258115 5.07858411497863 6.48049366810288e-07 -165.136372506099 55.7544241601441 -2.96185235510237 0.00328755075853486 TAF9 other 1.5688877737855e-07 1 0.00779020143842647 5.07858411497863 -2.96185235510237 0.000102204283681751 29.6756528843974 7.22090340482774 4.10968700461454 5.03917500285729e-05 4.55103307812284 15.7604153123341 0.288763524814045 0.772949314341 HIST1H3G other 0.879365656797788 1 0.53742801405473 4.10968700461454 0.288763524814045 0.903938330631662 57.6942069958261 128.567703981864 0.448745720806872 0.653922665435815 30.1471410063947 394.688737088965 0.0763820655961595 0.939163473501742 RN7SL2 other 1 1 1 0.448745720806872 0.0763820655961595 0.00132063554891388 12.8210824029063 3.51800352205544 3.64442000200598 0.000314277643287367 -8.77067471680252 14.3277507297935 -0.612145959418777 0.540891364013068 LINC01138 other 1 1 1 3.64442000200598 -0.612145959418777 0.00716072035608203 139.234167281402 44.1011053394547 3.15715822108516 0.00174486057426473 81.6471442248832 182.489948493185 0.447406253873387 0.654884457880843 INO80B-WBP1 other 1 1 1 3.15715822108516 0.447406253873387 0.00356078574680251 13.3822475723579 3.98630588155255 3.35705486984503 0.000883981910313416 18.6274873782116 13.7966483708455 1.35014583814243 0.177935441794522 CASTOR2 other 1 1 1 3.35705486984503 1.35014583814243 0.0204536833797585 47.2135944453098 16.9388162986538 2.78730187593227 0.00563247157466245 -3.38102102188752 31.3156599991969 -0.107965823551994 0.914090464831356 NATD1 other 1 1 1 2.78730187593227 -0.107965823551994 0.000625192085913593 107.518920979451 28.7621438058051 3.73820956133842 0.000219717787447101 -50.9286257326298 70.2089965102558 -0.725386036890448 0.468748698528093 SOCS7 other 1 1 1 3.73820956133842 -0.725386036890448 0.043999298166406 -1.04856163058017 1.61932777133152 -0.647528961797505 0.517755379755424 -9.95387204560674 4.01753037384043 -2.47760965552866 0.0137440407898461 TBC1D3H other 1 1 1 -0.647528961797505 -2.47760965552866 0.0224789286594424 -1.77614916041451 40.5286259195598 -0.0438245590644934 0.965080690295263 -196.396399179194 76.0408581181786 -2.58277462984394 0.0103942969305214 CBSL other 1 1 1 -0.0438245590644934 -2.58277462984394 0.192221829785408 11.7143999524362 6.58624633071895 1.77861552152991 0.076298823852618 -2.71232795267394 21.8837256711275 -0.1239426957473 0.901442287723894 ADRA2B other 1 1 1 1.77861552152991 -0.1239426957473 0.000781727317050849 13.8499355489169 3.64647909013832 3.79816672646586 0.000174416024939434 8.4342353665592 7.95884138955506 1.05973155560407 0.290065964699422 HIST1H2BE other 1 1 1 3.79816672646586 1.05973155560407 0.0171132505361242 12.7023466628967 5.68890251705177 2.2328290254268 0.0263078197202903 -15.4428966008457 11.022427690404 -1.40104313084224 0.162248699039785 ZNF658 other 1 1 1 2.2328290254268 -1.40104313084224 4.74556678120241e-05 4.58046990193316 1.09403040064191 4.18678484550852 3.66412966824807e-05 -3.39166263330515 3.42363118036636 -0.990662385818736 0.322601291697476 TMEM269 other 0.424680771249803 1 0.395359591203967 4.18678484550852 -0.990662385818736 0.363236578896131 -0.497806240760944 2.06372877369371 -0.241216892019177 0.809541988789754 -7.1646024903536 5.03798645591081 -1.42211626669773 0.155969510143301 TBC1D3D other 1 1 1 -0.241216892019177 -1.42211626669773 2.99597587563004e-10 226.576553219572 37.7008837157199 6.00984727382127 5.11418523236436e-09 -202.693715600953 130.483171977094 -1.55340886130923 0.12132641127812 RCC1L other 3.69583584017722e-06 1 6.67043179857284e-05 6.00984727382127 -1.55340886130923 1.23562664923354e-09 72.2065099758971 11.1180644255798 6.49452163721671 3.29642263110458e-10 14.1823889596866 40.15618073844 0.353180723337822 0.724192228193153 PI4KAP1 other 1.4878180483421e-05 1 4.43335879657255e-06 6.49452163721671 0.353180723337822 0.113891445957808 0.585910823332728 2.07356334867513 0.282562297268172 0.777695635668975 -10.2907327250315 5.06199467646169 -2.03294025038855 0.04288628267425 TBC1D3 other 1 1 1 0.282562297268172 -2.03294025038855 1.57337764090166e-06 31.1597474529766 6.5334484548321 4.76926506245427 2.81699033250604e-06 -3.3565644436234 14.2101805673964 -0.236208430125416 0.813422528293361 HIST1H3E other 0.0160405850489924 1 0.0327418786347177 4.76926506245427 -0.236208430125416 5.76499317807157e-07 81.6436695943314 16.8252210586454 4.85245746904347 1.90845515440297e-06 -128.394844864357 69.0051364546881 -1.86065634329506 0.0637098073368251 NPHP3-ACAD11 other 0.00606823181923814 1 0.0223899958714556 4.85245746904347 -1.86065634329506 0.00843288188567789 3.19319873757814 1.06681433514956 2.99320943895122 0.00297553219475093 2.124708048535 1.98835194602167 1.06857744816563 0.286065534520677 PANO1 other 1 1 1 2.99320943895122 1.06857744816563 0.0487947398398926 -0.450481283300342 1.5951336571452 -0.28240974120411 0.777812491138067 -9.77082739852404 3.95750510265534 -2.46893614665668 0.0140751300791366 TBC1D3I other 1 1 1 -0.28240974120411 -2.46893614665668 0.47048371837938 -3.66133719991394 3.09238831541268 -1.18398364838775 0.237298254221814 1.03215287315378 10.0055737766504 0.103157789467553 0.917902357266784 ZNF280B other 1 1 1 -1.18398364838775 0.103157789467553 0.085339462092493 115.800007510011 127.058604913125 0.911390516125907 0.362779999377149 -609.507324606078 311.458254634322 -1.95694708853259 0.0512283889257951 MLLT6 other 1 1 1 0.911390516125907 -1.95694708853259 6.02950640932132e-07 347.39562883344 66.3824293121039 5.23324669544894 3.01975372682239e-07 -229.436583034482 262.861473521014 -0.872842185510082 0.383403579429474 PPP4R3B other 0.00633640828555578 1 0.00368621337433209 5.23324669544894 -0.872842185510082 0.0270011271247933 61.7080691663906 30.4577352272579 2.02602290373729 0.0435970051662093 -114.992409689194 74.6664511470718 -1.54008136080676 0.12453497329414 SYNRG other 1 1 1 2.02602290373729 -1.54008136080676 1.44162069404174e-12 37.601260638538 13.8373698197841 2.71737050669682 0.00693850503409212 -99.6282134442924 25.5881468659304 -3.89352984279387 0.000120272483219051 NUDT18 other 1.89313629541561e-08 1 1 2.71737050669682 -3.89352984279387 5.20934157490502e-05 12.486710312646 3.43668220471798 3.63336193713341 0.000328647387367534 -25.7191092113192 11.7628665114171 -2.18646612935342 0.029548765194434 ZNF2 other 0.46404814749254 1 1 3.63336193713341 -2.18646612935342 0.00981431021608689 43.0508762596655 15.0762888443568 2.85553538434493 0.00457891283592184 -11.6665571059713 38.3222832487291 -0.304432724695707 0.760997365455448 LENG9 other 1 1 1 2.85553538434493 -0.304432724695707 0.0263752936517856 -54.6532185553109 20.1534844744802 -2.71184958732654 0.00705358156010132 -12.7620061073112 50.0005233334378 -0.255237450660374 0.798704188884782 CCL4 other 1 1 1 -2.71184958732654 -0.255237450660374 5.67021168014919e-10 188.089135679861 57.179627978304 3.28944315187271 0.00111608175893246 -266.447160465242 110.764484606942 -2.40552882461155 0.0167179546403724 PRAG1 other 6.92276144029414e-06 1 1 3.28944315187271 -2.40552882461155 0.545861812436091 -73.4678206182296 95.4257119409154 -0.769895441426924 0.441931657190123 -204.997182627259 235.905611602998 -0.868979678924492 0.385511567545172 CCL18 other 1 1 1 -0.769895441426924 -0.868979678924492 0.0573562914074588 -586.537597344735 279.826465212503 -2.09607621244586 0.036860566831308 -1469.91996377748 877.76888965908 -1.67460932039683 0.0949878783902325 FCGBP other 1 1 1 -2.09607621244586 -1.67460932039683 0.75779257555136 -5.64611478933172 15.798897362448 -0.357373977424009 0.721048169428372 23.8094225914866 39.0570682590134 0.609605985620593 0.54255679696414 CCL15 other 1 1 1 -0.357373977424009 0.609605985620593 1.16832272075183e-09 298.379196747399 58.4896421991098 5.10140232575983 5.80745069326508e-07 -507.573149549758 144.027409078529 -3.52414275030812 0.000487178422262345 AATF essential 1.40771204623388e-05 1 0.00699855883045374 5.10140232575983 -3.52414275030812 0.00017075476483544 25.6785049716991 6.48423812985496 3.96014218747908 9.23628126699367e-05 2.71518457369246 14.1525623846819 0.191851093808373 0.847980528786257 HIST1H2BH other 1 1 0.960942703018022 3.96014218747908 0.191851093808373 0.344989440098375 -0.912609433625144 1.57283822573412 -0.580230959989026 0.562167216834686 3.96549255710296 3.61561101000158 1.09676968737332 0.273566746657671 HNRNPCL2 other 1 1 1 -0.580230959989026 1.09676968737332 0.00426687126695127 4.42166271182884 1.534572725356 2.88136406881798 0.00423401056989299 -5.04580472200639 5.55821105855807 -0.907810924926515 0.364678764427041 RIMBP3 other 1 1 1 2.88136406881798 -0.907810924926515 0.0284894942654745 341.744008048267 164.248761221448 2.08064892244461 0.0382662149055117 -602.014112897681 400.934672368998 -1.50152669346497 0.134211666185706 ARHGAP23 other 1 1 1 2.08064892244461 -1.50152669346497 0.00166939342596027 37.687906572454 19.0592901751309 1.97740347233027 0.0488731019389981 -84.4976275484775 41.5588435825567 -2.03320449426421 0.0428753192656708 TUBGCP5 essential 1 1 1 1.97740347233027 -2.03320449426421 0.126522964439367 -38.1551160662598 22.1871867453697 -1.71969148248245 0.0864554405695903 -62.5652959082677 37.0921044601491 -1.68675508760864 0.092625011171192 PICSAR other 1 1 1 -1.71969148248245 -1.68675508760864 0.00015032247640605 24.5649179018192 38.0925570173114 0.644874480089524 0.519624469367797 -261.456497336171 71.470242520955 -3.6582567529348 0.000312148494278601 U2AF1L5 other 1 1 1 0.644874480089524 -3.6582567529348 0.0922283346904142 -0.28214145236177 1.30903309408423 -0.21553423946027 0.829488560662564 -7.1173667886264 3.24769346203539 -2.19151433835317 0.0291372923161077 TBC1D3F other 1 1 1 -0.21553423946027 -2.19151433835317 0.0034240220232644 269.546231611546 82.1032168230746 3.28301669583051 0.00114134731337976 -99.3483313792716 201.274184774292 -0.493596988062233 0.62193155293639 DUSP14 other 1 1 1 3.28301669583051 -0.493596988062233 6.12009338140825e-06 18.7697314611973 66.206524845988 0.283502743949484 0.776974805974751 -545.668817045942 125.648723396871 -4.34281226497151 1.89036492849911e-05 UHRF1 other 0.0595261801672028 0.276239027001575 1 0.283502743949484 -4.34281226497151 0.958120439789724 19.3785044982662 81.9238871440682 0.236542785917713 0.813165742438455 -29.2382488016087 251.064453553999 -0.116457142330267 0.90736469731092 RN7SL1 other 1 1 1 0.236542785917713 -0.116457142330267 0.00341481215120697 68.5608247892423 21.6577648074183 3.16564638128116 0.00169625580463983 1.7439962205087 49.1461685559753 0.035485904023675 0.971714411526576 HIST1H4I other 1 1 1 3.16564638128116 0.035485904023675 0.0413988564204736 -3.7385215682056 2.61008905605583 -1.43233486977451 0.153027160830896 -10.3668098516483 4.80553025927722 -2.15726658502147 0.0317313647279595 PIK3R6 other 1 1 1 -1.43233486977451 -2.15726658502147 0.21222261527698 9.8300481616352 14.8732035280376 0.660923394418994 0.509138466617821 -56.43369200047 36.4658982637125 -1.54757443769396 0.12271626234821 TADA2A essential 1 1 1 0.660923394418994 -1.54757443769396 5.91311617934763e-06 200.263832263939 40.8060046776178 4.90770497739477 1.47464277914586e-06 -58.6105715899473 100.027597534073 -0.58594400980172 0.558328772695588 PIP4K2B other 0.0576114909353839 1 0.0174273283639458 4.90770497739477 -0.58594400980172 0.745736134118395 -3.8851298916728 15.7143606671802 -0.247234359319942 0.804885897983727 26.9250779638525 38.8480818087746 0.693086420492733 0.488759607847375 CCL14 other 1 1 1 -0.247234359319942 0.693086420492733 0.229199157561052 11.1770888644387 15.7461903594531 0.709828130442273 0.478327636407844 -38.0379646752745 32.9154965653116 -1.15562481640825 0.248696764982797 FAM25C other 1 1 1 0.709828130442273 -1.15562481640825 0.001307666870137 565.221111907246 155.394554913784 3.63732894129297 0.000321282426666288 415.247624158293 235.223480265756 1.76533237111 0.0784676209067905 PCDHGB5 other 1 1 1 3.63732894129297 1.76533237111 0.022065638943864 89.5558050062687 38.6706473957499 2.31585998780334 0.0212139478277276 -46.501802727799 84.6068842056331 -0.549621974197496 0.582971876638304 HERC2P2 other 1 1 1 2.31585998780334 -0.549621974197496 0.84794444477832 -22.5576950405002 49.2932173747119 -0.457622696222556 0.647534088438678 -59.4041494955233 167.401341323212 -0.354860654197675 0.722927743256935 RAB7B other 1 1 1 -0.457622696222556 -0.354860654197675 0.0421989467735526 -8.82821469575204 5.00512009011171 -1.76383673854167 0.078767190440576 12.9615965502159 10.4308044035043 1.24262674754608 0.214966201627336 DACH1 other 1 1 1 -1.76383673854167 1.24262674754608 3.7490287957121e-08 349.760967146266 71.9070749787131 4.86406890072788 1.8169470193826e-06 -527.654832187489 252.75038920737 -2.0876519076478 0.0376298985179277 GTF2IP1 other 0.000422965428732239 1 0.0213345919015905 4.86406890072788 -2.0876519076478 3.98219375983254e-06 40.4982637819788 8.7805185786601 4.61228609895599 5.77362655789016e-06 -3.51437896422196 19.0975340726623 -0.18402265710591 0.854112602499184 HIST1H2AE other 0.0393440743471455 1 0.0658597581458531 4.61228609895599 -0.18402265710591 2.43887776618597e-06 31.656533322048 6.13267217168656 5.16194775063968 4.35980287647359e-07 -16.992151676418 24.9206966656042 -0.681848982972885 0.495840286138875 LINC00869 other 0.0244887716502734 1 0.00528408108628599 5.16194775063968 -0.681848982972885 6.56473060312279e-07 31.363388054635 6.30593615467154 4.97362917818323 1.08212889556951e-06 -18.9762415529604 21.6891656609107 -0.874918005129184 0.382285122004222 TYW1B other 0.00688312003737424 1 0.0128805802439639 4.97362917818323 -0.874918005129184 3.30035541165268e-06 58.1717794037806 13.7448498027336 4.23226010023124 3.02820074770294e-05 -84.3273411502502 34.1007870944811 -2.47288547670789 0.013923507295341 PIGW other 0.0328055327918277 1 0.328680909155677 4.23226010023124 -2.47288547670789 0.190525163753047 -2.34410777046382 2.80926751867914 -0.834419561283353 0.404667070358643 -14.5805297972498 8.3295667062502 -1.75045477291264 0.0809981994174539 RPPH1 other 1 1 1 -0.834419561283353 -1.75045477291264 7.74918614079077e-06 10.5308927068579 2.25942956020159 4.6608634729548 4.63331504882424e-06 1.44550157029374 4.91423514729523 0.294145788096717 0.768837806016671 HIST1H2BF other 0.0747331511417862 1 0.053144123610014 4.6608634729548 0.294145788096717 2.46617119142623e-07 195.516570366441 35.2177543565709 5.55164785315057 5.97548254891108e-08 -54.3592021866645 86.3291416707881 -0.629673840543447 0.529360136944197 PCGF2 other 0.0026627250353829 1 0.000750580362968721 5.55164785315057 -0.629673840543447 0.152584136950511 10.8988950139443 5.71047136693599 1.90858062559417 0.0572163480432345 7.55704539806194 13.939380422408 0.54213639122107 0.58810423597913 SRCIN1 other 1 1 1 1.90858062559417 0.54213639122107 0.418922015980265 -2.36905637521656 2.23373732259917 -1.06057966227646 0.289680788694004 -5.90723725946189 5.21387355440753 -1.13298437290798 0.258068981029115 MIR6891 other 1 1 1 -1.06057966227646 -1.13298437290798 3.68986997313721e-07 740.470040873365 225.66735544058 3.28124570533348 0.00114792862395935 -1852.8747555029 516.808096343049 -3.58522780237753 0.000389485566669201 MARCKS other 0.00394188809230248 1 1 3.28124570533348 -3.58522780237753 0.000309161613862668 8.90656565735375 2.40774176916867 3.69913658158987 0.000254554796548125 -8.55691354653484 11.1152878941449 -0.769832830964486 0.441966968483883 CEBPB-AS1 other 1 1 1 3.69913658158987 -0.769832830964486 0.0043824800896217 10.9139321346054 3.37612391081791 3.23268115238145 0.0013541576055964 9.20153891059478 10.7270717876452 0.857786644179316 0.391652277830097 ZNF670 other 1 1 1 3.23268115238145 0.857786644179316 0.490474894726391 -0.0611154726244167 1.65946648987129 -0.0368283861092953 0.970644803965641 -9.74740940885132 8.17879621699962 -1.19179022807676 0.234226623025688 GPIHBP1 other 1 1 1 -0.0368283861092953 -1.19179022807676 0.0676551939258795 29.274622392356 233.970382589067 0.125121060488123 0.900506522742955 -749.357228701149 431.721611934912 -1.73574175576395 0.0835751226086386 NEFL other 1 1 1 0.125121060488123 -1.73574175576395 0.206505354054037 -32.5150691649718 18.262335637331 -1.78044417815354 0.0759549587995104 -10.0446919670547 45.1470297700402 -0.222488434304939 0.82407605725668 CCL3 other 1 1 1 -1.78044417815354 -0.222488434304939 0.0445094127201729 0.207915358878708 0.757303321001298 0.274547005292153 0.783857760778441 -4.44800304106924 1.92368668048883 -2.31222843417461 0.0214582281604813 PGM5P2 other 1 1 1 0.274547005292153 -2.31222843417461 0.849862642943629 59.143684316751 175.306643826294 0.337372748835204 0.736058499230209 -186.116276850241 429.728481193942 -0.433102028362518 0.665234260734528 PSMB3 essential 1 1 1 0.337372748835204 -0.433102028362518 0.0653846562204738 93.2600153016438 42.0080703606009 2.22004996899624 0.027120177051742 -60.3461738848811 102.974216378453 -0.586031882613172 0.558269794075529 CISD3 other 1 1 1 2.22004996899624 -0.586031882613172 1.48682604665245e-05 7.84287476796643 1.66246620873716 4.71761454563579 3.57044535946719e-06 -2.10712475438557 3.17331209181775 -0.664014346341382 0.507159268250742 SNORA67 other 0.139821121427196 1 0.0412537630705747 4.71761454563579 -0.664014346341382 0.238383720757437 0.887608002654093 2.6471357687128 0.335308831962822 0.737612529706217 -10.5733616051466 6.54408722568419 -1.61571220561492 0.107145082629872 RDM1 other 1 1 1 0.335308831962822 -1.61571220561492 1.54041218910723e-06 118.007500243438 24.3847721777089 4.83939318290261 2.03451433291246e-06 -94.1403611896839 59.5322898359678 -1.58133277670107 0.114796038612468 DDX52 essential 0.0157229872142175 1 0.0238384044387353 4.83939318290261 -1.58133277670107 0.000507962625360112 35.7417878405375 11.2225817006721 3.18480976960916 0.00159294268698437 -36.9584248556351 28.5196467103112 -1.29589350215453 0.195957901110979 ZNF8 other 1 1 1 3.18480976960916 -1.29589350215453 6.2590210096086e-07 10.3842675933221 2.13086327560346 4.87326789673135 1.73517301849734e-06 -0.983254692979127 3.96324345166508 -0.248093437854803 0.804222239545872 TSC22D1-AS1 other 0.00657322386429095 1 0.0204108402165842 4.87326789673135 -0.248093437854803 0.0983618532113728 4.21133101836569 2.0229168576456 2.08181122345637 0.0382245315503357 0.18713535225506 5.14299617448317 0.0363864459366171 0.970998914599412 GLIDR other 1 1 1 2.08181122345637 0.0363864459366171 0.0350802208425721 -268.144616472299 112.575305449624 -2.38191329262962 0.0178070225903277 -541.433573357147 361.555391963097 -1.49751209743377 0.13524577573908 MIR650 other 1 1 1 -2.38191329262962 -1.49751209743377 4.78575887930344e-06 153.720891080574 61.1552740264483 2.51361625841286 0.0124423018999777 -624.401353336329 151.725410550926 -4.11533803776892 4.9269711040057e-05 MYO19 other 0.0469913664358805 0.710961930308023 1 2.51361625841286 -4.11533803776892 0.0142899854907312 0.599891614418296 1.82402065194059 0.328884222763633 0.742459005807763 -10.0665592846551 3.65494345890515 -2.75423119340692 0.00622053574312299 SNORA61 other 1 1 1 0.328884222763633 -2.75423119340692 0.0936763039693993 0.0261550886241003 1.64501297225676 0.0158996245410872 0.987324408939342 -8.71953679564743 4.01581505266986 -2.17129939533703 0.0306453307336147 TBC1D3C other 1 1 1 0.0158996245410872 -2.17129939533703 0.0170591604153957 78.6099787098487 35.341424599434 2.22430135742484 0.026827742358866 -140.167919834304 88.0041338219285 -1.59274245137082 0.112208341458912 GGNBP2 other 1 1 1 2.22430135742484 -1.59274245137082 2.02199447238538e-40 103.962497460477 6.64078561262431 15.6551503880567 2.36634871915792e-41 28.8506632594832 27.5619478770125 1.04675705027167 0.296006609269747 ZNF229 other 3.08920315491039e-36 1 3.61956700082395e-37 15.6551503880567 1.04675705027167 0.000162782314341533 43.5983110720126 10.6866863124696 4.07968474017439 5.70282713353943e-05 -19.5601421270652 26.6110543933932 -0.735038222759088 0.462856236803638 DHRS11 other 1 1 0.604784817511856 4.07968474017439 -0.735038222759088 2.67692481277264e-07 378.423211558794 84.3348864306563 4.48714912149611 1.00905799565087e-05 -590.721986080114 206.771014923899 -2.85688971588946 0.00455901858814639 ACACA other 0.00288545725568763 1 0.113216307112028 4.48714912149611 -2.85688971588946 0.00272728303050795 5.13814802361097 1.49707227512482 3.4321309057591 0.000679901037527637 1.93750971311347 5.40711967094803 0.358325657840261 0.720342718689472 TMEM191B other 1 1 1 3.4321309057591 0.358325657840261 0.119584288113698 -0.136438128432906 3.04300789077856 -0.0448366002751305 0.964265605086454 -15.3116628765875 7.42860822332432 -2.06117517794409 0.0400964448894707 TBC1D3E other 1 1 1 -0.0448366002751305 -2.06117517794409 0.0305180300011759 66.3689698391715 45.1996572876111 1.46835117392279 0.143013080505238 -281.818033513634 165.699284560825 -1.70078002606091 0.089977519706947 C11orf98 other 1 1 1 1.46835117392279 -1.70078002606091 7.0251979626455e-05 34.9372144591646 8.26865589871668 4.22525920622564 3.11872037936123e-05 -19.5264474582188 20.5898859054424 -0.94835141621924 0.343668451481158 MRM1 other 0.61610986132401 1 0.338131663530344 4.22525920622564 -0.94835141621924 0.212351025866875 2.70777999666839 4.23315725987891 0.639659674903229 0.522857334607893 -10.975636037045 8.33495009989664 -1.31682084541587 0.188852853990029 GOLGA6L10 other 1 1 1 0.639659674903229 -1.31682084541587 4.00495271476275e-06 38.0689937813173 7.81984077903585 4.86825689384574 1.77177945104332e-06 92.5786806509681 36.5810432050497 2.53078295586137 0.0118597036918177 NKILA other 0.0395489080582821 1 0.0208290392264653 4.86825689384574 2.53078295586137 0.357323562729883 246.585406113137 180.053954871183 1.36950841368385 0.171819039899153 -12.2073972040249 408.445338341601 -0.0298874685498682 0.976175787178326 MIR6723 other 1 1 1 1.36950841368385 -0.0298874685498682 0.00126197421562638 4.95736128683789 1.35816819109404 3.65003489210316 0.00030776616313697 2.59331276405259 5.53140301569695 0.468834535594915 0.639518502127226 LINC00624 other 1 1 1 3.65003489210316 0.468834535594915 1.88451669650393e-05 68.4179617917135 15.5656057054175 4.39545772175773 1.50583557334743e-05 1.63784767896179 35.4026388983604 0.0462634348717335 0.963129140495277 HIST1H3H other 0.175410814110586 1 0.16690681494983 4.39545772175773 0.0462634348717335 7.59904598271674e-05 96.2680603565462 21.9654611929925 4.38270152903769 1.59441398811126e-05 -9.94386481920232 53.8230075865069 -0.184751192196387 0.853541960188983 MRPL45 essential 0.663548695210826 1 0.17640596364463 4.38270152903769 -0.184751192196387 4.37997870488641e-07 45.0893419219787 22.2990706938101 2.02202784775667 0.0440131176314 -149.97565192355 35.7161052240429 -4.19910432514324 3.48583014880425e-05 HEIH other 0.00464890939736644 0.505619663084056 1 2.02202784775667 -4.19910432514324 9.5487375971392e-07 5.15289198753324 0.968301895165989 5.3215758569283 1.93862348836684e-07 -1.03786807590412 1.84829267284438 -0.561527993457294 0.57483069367971 C17orf100 other 0.00990490550951249 1 0.0023854762024354 5.3215758569283 -0.561527993457294 0.00198070536756912 3.86466337573655 1.08987239184335 3.54597786370207 0.000449570228605137 1.67565274299723 2.13492478863548 0.784876709435844 0.433106529866001 MIR3911 other 1 1 1 3.54597786370207 0.784876709435844 0.74891029065926 -0.245850463796676 0.539548657515655 -0.4556594857055 0.648961230426408 1.29806581495703 2.07462535946256 0.625686854272956 0.531991346979489 PPIAL4F other 1 1 1 -0.4556594857055 0.625686854272956 0.253403697145109 1.23543687684125 1.35002631621622 0.915120588392582 0.360817385231915 4.44497664102685 2.7982868475733 1.58846354328598 0.113169072910804 GABARAPL3 other 1 1 1 0.915120588392582 1.58846354328598 0.0228506459649204 -3.8379328766902 2.26372462341054 -1.69540625083097 0.0912952548523753 -11.353452167253 4.24725879552487 -2.67312464670521 0.00803046105071828 LINC01670 other 1 1 1 -1.69540625083097 -2.67312464670521 0.00033267104883565 10.4540672187043 2.82704301617449 3.69788049169857 0.000256148143924991 31.4819956951594 12.7534458006398 2.46850899649255 0.0140949450894752 UCKL1-AS1 other 1 1 1 3.69788049169857 2.46850899649255 0.247037447835587 12.7061765502969 16.3426515616013 0.777485618071388 0.437446718837195 -55.4257682813554 41.9244878486725 -1.32203805283003 0.187099709809371 THRIL other 1 1 1 0.777485618071388 -1.32203805283003 0.0620889285275368 -5.19600633758726 3.29955547347296 -1.5747595030182 0.116303168338226 -16.9671245459089 8.3720216124427 -2.02664605173642 0.0435301913341379 CCDC163 other 1 1 1 -1.5747595030182 -2.02664605173642 5.0210792477465e-05 39.6828542592735 27.4066308590744 1.44792895060045 0.148615950852733 -162.998759113622 50.4353489352499 -3.23183565802001 0.00135804212931244 SH3PXD2A-AS1 other 0.44803090127642 1 1 1.44792895060045 -3.23183565802001 0.00130764157994904 109.825713341141 35.7201117903332 3.07461841065298 0.00229101199845249 -142.405458102845 129.34183384301 -1.10100076573595 0.271731629237457 PAGR1 other 1 1 1 3.07461841065298 -1.10100076573595 1.74784339925193e-21 105.678675328303 12.4393445511748 8.49551798276399 7.55451893444549e-16 -95.2910181591789 34.3193414305022 -2.77659809854296 0.00581672119853769 LINC00294 other 2.56163928594363e-17 1 1.0954052454946e-11 8.49551798276399 -2.77659809854296 1.27568640501031e-23 182.331245361951 23.3340463144566 7.81395746390494 8.22369419746971e-14 -105.932156560138 43.0450852028613 -2.46095822695912 0.0143892532408028 CTBP1-AS other 1.89069482086578e-19 1 1.17162971231351e-09 7.81395746390494 -2.46095822695912 0.0452713853981713 3.06843300193524 1.22931301070367 2.49605509355087 0.0130612279010946 1.89241492334637 3.53284332326286 0.535663416173964 0.592563286902766 LINC00921 other 1 1 1 2.49605509355087 0.535663416173964 0.0623741075132446 2.87883535406673 1.81088262284312 1.58974155351212 0.112889857545763 -2.86899868308836 3.17089524662135 -0.90479137907357 0.366263038960294 N4BP2L2-IT2 other 1 1 1 1.58974155351212 -0.90479137907357 0.00553441317561042 -7.21465826223302 2.3170223203574 -3.11376295292665 0.00201407334187974 -13.7836383278137 9.49720414232235 -1.45133642714804 0.147665819746418 TRG-AS1 other 1 1 1 -3.11376295292665 -1.45133642714804 5.03772245334214e-06 8.8475464217703 1.86454069100879 4.74516134962086 3.14904822942709e-06 -4.86187566580667 5.80144603679172 -0.838045486413824 0.402632628283933 SLFNL1-AS1 other 0.0493696800427529 1 0.0365037670755189 4.74516134962086 -0.838045486413824 5.02639037130211e-07 132.221623715813 25.1626095095289 5.25468646905411 2.77961331614299e-07 -157.137043156713 155.600544276856 -1.00987463692365 0.313350625182106 ABALON other 0.00531188934439207 1 0.00339946708564288 5.25468646905411 -1.00987463692365 0.485633583492669 -13.0733932498062 13.2190034625514 -0.98898478140522 0.323417791542498 8.86395528247501 30.6860661032373 0.288859290488848 0.772876091982069 PANDAR other 1 1 1 -0.98898478140522 0.288859290488848 0.01791635148959 40.6060150202081 15.0791983874882 2.69284971102314 0.00745752831381441 -51.5359948275486 49.236529696512 -1.04670242084912 0.29602680850309 TGFB2-OT1 other 1 1 1 2.69284971102314 -1.04670242084912 1.24224516923562e-29 302.077444902872 26.9323767036324 11.2161450965495 9.10779247902134e-25 -303.654984485151 82.2665445141772 -3.69111145093521 0.000263304569728407 EBLN3P other 1.87579020554579e-25 1 1.37179481603356e-20 11.2161450965495 -3.69111145093521 4.49692852662407e-07 3.78810386310188 4.22958304394618 0.895621110578218 0.3711325927638 -24.8310534994999 5.99563863704971 -4.14151936143346 4.42574753149202e-05 RBM5-AS1 other 0.00476899270248483 0.639653290726541 1 0.895621110578218 -4.14151936143346 0.000876629010961669 -78.7172454672179 22.0551129941407 -3.56911549209158 0.000413068602962362 -143.234272281075 49.0942920592899 -2.91753412205424 0.00377773454103476 GIMAP1-GIMAP5 other 1 1 1 -3.56911549209158 -2.91753412205424 0.675974758971653 2.05906939977694 2.3874806049109 0.86244445108436 0.389259738552584 2.20464758687153 4.3587619512956 0.505796740337292 0.613439745554063 LINC02246 other 1 1 1 0.86244445108436 0.505796740337292 0.000473699162170499 34.0061430378897 51.5538013075306 0.65962435699038 0.50997996436225 -631.28033783934 177.405627845395 -3.55840085518305 0.000430934146434792 TMEM265 other 1 1 1 0.65962435699038 -3.55840085518305 0.24228438536271 -5.9990480540603 6.28048470067658 -0.955188705963099 0.340203290458674 -19.2505965670183 11.5095885704626 -1.67257034855458 0.0953892602546377 ADORA3 other 1 1 1 -0.955188705963099 -1.67257034855458 0.000356242348444055 34.3386838258175 10.9070465888475 3.14830266342942 0.00179793592972561 -37.8996342329754 25.4449086785108 -1.48947809999346 0.137352612205398 BISPR other 1 1 1 3.14830266342942 -1.48947809999346 0.425615478424717 -4.99470778805749 3.8762916440439 -1.28852734693791 0.198514075268325 2.82633169591503 22.5189595678717 0.125508982215476 0.900201189761216 PRNCR1 other 1 1 1 -1.28852734693791 0.125508982215476 4.65683755381436e-08 89.8193148291402 18.1485713310174 4.94911214722625 1.20943014398055e-06 -108.910273290277 49.2663975961494 -2.21064008339001 0.0277700152322222 PCBP2-OT1 other 0.000522450605162433 1 0.0143668206803449 4.94911214722625 -2.21064008339001 0.55965087514184 3.25653690161854 4.09270210433914 0.795693607449686 0.426803684088601 -2.99250004712657 7.41661145936008 -0.40348615584411 0.686861785869288 GTF2IP12 other 1 1 1 0.795693607449686 -0.40348615584411 1.32916435553743e-08 68.4068045175567 11.1128183876555 6.15566655831839 2.28771238248429e-09 -54.3220881521996 65.50049966941 -0.82933853064283 0.407544898114022 IQCJ-SCHIP1 other 0.000153332400054798 1 3.01566246259079e-05 6.15566655831839 -0.82933853064283 0.000421213101521929 12.4869338622584 3.13361518058718 3.98483321743375 8.36747099769172e-05 11.9378428853668 12.6596912475964 0.942980571317915 0.34640221447313 TXNRD3NB other 1 1 0.874484393968761 3.98483321743375 0.942980571317915 0.97432442402581 -0.553600827348107 2.88963402489305 -0.191581640643436 0.848192193488866 -2.31726861057986 15.1026304754469 -0.153434768489314 0.878152746865644 MIR1244-3 other 1 1 1 -0.191581640643436 -0.153434768489314 0.925616358047594 -1.65581406235371 4.21141008294765 -0.393173314814018 0.694453283435859 -1.61903535873667 19.1634185636578 -0.0844857274999497 0.932723080148978 MIR1244-4 other 1 1 1 -0.393173314814018 -0.0844857274999497 0.476400333390731 -47.2669189550457 76.2677515011232 -0.619749737270668 0.535863596421017 -137.605782107075 113.889292568481 -1.20824160905498 0.227846464247714 MIR1244-2 other 1 1 1 -0.619749737270668 -1.20824160905498 0.0144472701534396 5.22728923453022 2.1080887394216 2.47963434213136 0.0136661314344641 -0.341354142677555 3.13728867220956 -0.108805461767451 0.913424986217622 ZCWPW2 other 1 1 1 2.47963434213136 -0.108805461767451 0.0387400868151874 -53.8187914156688 23.7047879757344 -2.27037640964184 0.0238492662803826 -98.797860741816 49.5519772964199 -1.99382277221365 0.0470198714426132 WDFY4 other 1 1 1 -2.27037640964184 -1.99382277221365